LOCUS       DAPGUL010000001       106315 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.001, whole genome shotgun sequence.
ACCESSION   DAPGUL010000001 DAPGUL010000000
VERSION     DAPGUL010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 106315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 106315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..106315
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.001"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            119..1054
                     /locus_tag="RHX21_000001"
     CDS             119..1054
                     /locus_tag="RHX21_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001427098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HDV1985249.1"
                     /translation="MLTKRILFSVMLIVSPSVVASEKAHELYDSIYGGKPAPDVINTL
                     HKMAESGDIDAQSLLGWEYYQPRYDTKPDVQEAIKWFELAAKQGDREAPLALGGIYYD
                     GEQVRVDYAKAYALFNQAAQHGVNLAWSRLGIMYANGQYVEVDCKKAKEYLDKGVHIY
                     GGPEDFLATCRKDMIDRKTVDDTLPVITVTRSGMRDNFLDKGFSCMDSLFATTNKLGE
                     VANLRVTFSIRRPSGKEINQTVGFAPFGLNRLNISFTDYLFGSFTSNSSLILYKPEFE
                     RKSCATVRTTIVAATATINGKDVELLKAGAIEQKW"
     gene            complement(1110..1652)
                     /locus_tag="RHX21_000002"
     CDS             complement(1110..1652)
                     /locus_tag="RHX21_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDV1985250.1"
                     /translation="MVDKHEEITLPIVLSCNYQSDITYPGQKQFDCGNPVIDKFVRAS
                     LKKSVRNSDCAAKALIDRQSGELIGICTFTAYSLEKQRVSGVLQGSQPSEIGVVRLVM
                     LGVARKYQKRGFGQDLLCDFFEHVKIIHQALPIKGVYLDADPAAINFYARLGFVQLSA
                     TPNAFGAVPMFLAIQHILAA"
     gene            complement(1636..1947)
                     /locus_tag="RHX21_000003"
     CDS             complement(1636..1947)
                     /locus_tag="RHX21_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706319.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HDV1985251.1"
                     /translation="MPGKTATLPDVDKTLKNARVELKTSPDAKNKLREAAQAVGVDLS
                     AFILSAAMERAESVLDNQRRRELSNQSWELMNQLIAEPAQPTLALKALMKRKNSDGRQ
                     A"
     gene            complement(2132..3022)
                     /gene="cyoE"
                     /locus_tag="RHX21_000004"
     CDS             complement(2132..3022)
                     /gene="cyoE"
                     /locus_tag="RHX21_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX farnesyltransferase"
                     /protein_id="HDV1985252.1"
                     /translation="MMFKQYLQVTKPGIIFGNLISVIGGFLLASKGSIDYPLFIYTLV
                     GVSLVVASGCVFNNYIDRDIDRKMERTKNRVLVKGLISPAVSLVYATLLGIAGFMLLW
                     FGANPLACWLGVMGFVVYVGVYSLYMKRHSVYGTLIGSLSGAAPPVIGYCAVTGEFDS
                     GAAILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVVKGISVAKNHITLYIIAFAV
                     ATLMLSLGGYAGYKYLVVAAAVSVWWLGMALRGYKVADDRIWARKLFGFSIIAITALS
                     VMMSVDFMVPDSHTLLAAVW"
     gene            complement(3034..3363)
                     /locus_tag="RHX21_000005"
     CDS             complement(3034..3363)
                     /locus_tag="RHX21_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit IV"
                     /protein_id="HDV1985253.1"
                     /translation="MSHSTDHSGASHGSVKTYMTGFILSIILTVIPFWMVMTGAASPA
                     VILGTILAMAVVQVLVHLVCFLHMNTKSDEGWNMTAFVFTVLIIAILVVGSIWIMWNL
                     NYNMMMH"
     gene            complement(3363..3977)
                     /locus_tag="RHX21_000006"
     CDS             complement(3363..3977)
                     /locus_tag="RHX21_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit III"
                     /protein_id="HDV1985254.1"
                     /translation="MATDTLTHATAHAHEHGHHDAGGTKIFGFWIYLMSDCILFSILF
                     ATYAVLVNGTAGGPTGKDIFELPFVLVETFLLLFSSITYGMAAIAMYKNNKSQVISWL
                     ALTWLFGAGFIGMEIYEFHHLIVNGMGPDRSGFLSAFFALVGTHGLHVTSGLIWMAVL
                     MVQIARRGLTSTNRTRIMCLSLFWHFLDVVWICVFTVVYLMGAM"
     gene            complement(3967..5958)
                     /gene="cyoB"
                     /locus_tag="RHX21_000007"
     CDS             complement(3967..5958)
                     /gene="cyoB"
                     /locus_tag="RHX21_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002444673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit I"
                     /protein_id="HDV1985255.1"
                     /translation="MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWTYL
                     WKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQI
                     FTAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSL
                     GVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAP
                     GMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYI
                     NLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHH
                     FFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFS
                     VGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNE
                     TWGKRAFWFWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALG
                     ILCLVIQMYVSIRDRDQNRDLTGDPWGGRTLEWATSSPPPFYNFAVVPHVHERDAFWE
                     MKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFSTIFGFAMIWHIWWLAIVGFAGMIIT
                     WIVKSFDEDVDYYVPVAEIEKLENQHFDEITKAGLKNGN"
     gene            complement(5980..6927)
                     /gene="cyoA"
                     /locus_tag="RHX21_000008"
     CDS             complement(5980..6927)
                     /gene="cyoA"
                     /locus_tag="RHX21_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit II"
                     /protein_id="HDV1985256.1"
                     /translation="MRLRKYNKSLGWLSLFAGTVLLSGCNSALLDPKGQIGLEQRSLI
                     LTAFGLMLIVVIPAILMAVGFAWKYRASNKDAKYSPNWSHSNKVEAVVWTVPILIIIF
                     LAVLTWKTTHALEPSKPLAHDEKPITIEVVSMDWKWFFIYPEQGIATVNEIAFPANTP
                     VYFKVTSNSVMNSFFIPRLGSQIYAMAGMQTRLHLIANEPGTYDGISASYSGPGFSGM
                     KFKAIATPDRAEFDQWVAKAKQSPNTMSDMAAFEKLAAPSEYNQVEYFSNVKPDLFAD
                     VINKFMAHGKSMDMTQPEGEHSAHEGMEGMDMSHAESAH"
     gene            complement(7387..8862)
                     /gene="ampG"
                     /locus_tag="RHX21_000009"
     CDS             complement(7387..8862)
                     /gene="ampG"
                     /locus_tag="RHX21_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="muropeptide MFS transporter AmpG"
                     /protein_id="HDV1985257.1"
                     /translation="MSSQYLRIFQQPRSAILLILGFASGLPLALTSGTLQAWMTVENI
                     DLKTIGFFSLVGQAYVFKFLWSPLMDRYTPPFFGRRRGWLLATQILLLVAIAAMGFLE
                     PGTQLRWMAALAVVIAFCSASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSG
                     GLALWLADKWLGWQGMYWLMAALLIPCIIATLLAPEPTDTIPVPKTLEQAVVAPLRDF
                     FGRNNAWLILLLIVLYKLGDAFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGA
                     LYGGILMQRLSLFRALLIFGILQGASNAGYWLLSITDKHLYSMGAAVFFENLCGGMGT
                     SAFVALLMTLCNKSFSATQFALLSALSAVGRVYVGPVAGWFVEAHGWSTFYLFSVAAA
                     VPGLILLLVCRQTLEYTRVNDNFISRTEYPAGYAFAMWTLAAGVSLLAVWLLLLTMDT
                     LDLTHFSFLPALLEVGVLVALSGVVLGGLLDYLALRKTHLT"
     gene            complement(8906..9484)
                     /locus_tag="RHX21_000010"
     CDS             complement(8906..9484)
                     /locus_tag="RHX21_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414968.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDV1985258.1"
                     /translation="MFKKILFPLVALFMLAGCAKPPTTIEVSPTITLPQQDPSLMGVT
                     VSINGADQRTDQALAKVTRDNQIVTLTASRDLRFLLQEVLEKQMTARGYMVGPNGPVN
                     LQIIVSQLYADVSQGNVRYNIATKADIAIIATAQNGNKMTKNYRASYNVEGAFQASNK
                     NIADAVNSVLTDTIADMSQDTSIHEFIKQNAR"
     gene            9789..10106
                     /gene="bolA"
                     /locus_tag="RHX21_000011"
     CDS             9789..10106
                     /gene="bolA"
                     /locus_tag="RHX21_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414969.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator BolA"
                     /protein_id="HDV1985259.1"
                     /translation="MMIRERIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLV
                     SDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYTIKEWEGLQDTVFASPPCRGAG
                     SIA"
     gene            10450..11748
                     /gene="tig"
                     /locus_tag="RHX21_000012"
     CDS             10450..11748
                     /gene="tig"
                     /locus_tag="RHX21_000012"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001716227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HDV1985260.1"
                     /translation="MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGF
                     RKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAIIKEKINPAGAPTYVPGEYKLGED
                     FTYSVEFEVYPEVELQGLEAIEVEKPIVEVTDADVDGMLDTLRKQQATWKEKDGAVEA
                     EDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFP
                     EEYHAENLKGKAAKFAINLKKVEERELPELTAEFIKRFGVEDGSVEGLRAEVRKNMER
                     ELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPR
                     ELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNK
                     ELMDNMRNVALEEQAVEAVLAKAKVTEKETTFNELMNQQA"
     gene            11994..12617
                     /gene="clpP"
                     /locus_tag="RHX21_000013"
     CDS             11994..12617
                     /gene="clpP"
                     /locus_tag="RHX21_000013"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006809880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDV1985261.1"
                     /translation="MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIF
                     LTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVS
                     TICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK
                     GRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN"
     gene            12743..14017
                     /gene="clpX"
                     /locus_tag="RHX21_000014"
     CDS             12743..14017
                     /gene="clpX"
                     /locus_tag="RHX21_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001396736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATP-binding subunit ClpX"
                     /protein_id="HDV1985262.1"
                     /translation="MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLC
                     NDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNG
                     DTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
                     IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGT
                     VAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVISHRVETGSGIGFGATVKA
                     KSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALT
                     KQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMED
                     VEKVVIDESVIDGQSKPLLIYGKPEAQQASGE"
     gene            14205..16559
                     /gene="lon"
                     /locus_tag="RHX21_000015"
     CDS             14205..16559
                     /gene="lon"
                     /locus_tag="RHX21_000015"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001469947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HDV1985263.1"
                     /translation="MNPERSERIEIPVLPLRDVVVYPHMVIPLFVGREKSIRCLEAAM
                     DHDKKIMLVAQKEASTDEPGVNDLFTVGTVASILQMLKLPDGTVKVLVEGLQRARISA
                     LSDNGEHFSAKAEYLESPTIDEREQEVLVRTAISQFEGYIKLNKKIPPEVLTSLNSID
                     DPARLADTIAAHMPLKLADKQSVLEMSDVNERLEYLMAMMESEIDLLQVEKRIRNRVK
                     KQMEKSQREYYLNEQMKAIQKELGEMDDAPDENEALKRKIDAAKMPKEAKEKAEAELQ
                     KLKMMSPMSAEATVVRGYIDWMVQVPWNARSKVKKDLRQAQEILDTDHYGLERVKDRI
                     LEYLAVQSRVNKIKGPILCLVGPPGVGKTSLGQSIAKATGRKYVRMALGGVRDEAEIR
                     GHRRTYIGSMPGKLIQKMAKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNV
                     AFSDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKRHLLP
                     KQIERNALKKGELTVDDSAIIGIIRYYTREAGVRGLEREISKLCRKAVKQLLLDKSLK
                     HIEINGDNLHDYLGVQRFDYGRADNENRVGQVTGLAWTEVGGDLLTIETACVPGKGKL
                     TYTGSLGEVMQESIQAALTVVRARAEKLGINPDFYEKRDIHVHVPEGATPKDGPSAGI
                     AMCTALVSCLTGNPVRADVAMTGEITLRGQVLPIGGLKEKLLAAHRGGIKTVLIPFEN
                     KRDLEEIPDNVIADLDIHPVKRIEEVLTLALQNEPSGMQVVTAK"
     gene            16768..17040
                     /gene="hupB"
                     /locus_tag="RHX21_000016"
     CDS             16768..17040
                     /gene="hupB"
                     /locus_tag="RHX21_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein HU-beta"
                     /protein_id="HDV1985264.1"
                     /translation="MNKSQLIDKIAAGADISKAAAGRALDAIIASVTESLKEGDDVAL
                     VGFGTFAVKERAARTGRNPQTGKEITIAAAKVPSFRAGKALKDAVN"
     gene            17232..19103
                     /gene="ppiD"
                     /locus_tag="RHX21_000017"
     CDS             17232..19103
                     /gene="ppiD"
                     /locus_tag="RHX21_000017"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDV1985265.1"
                     /translation="MMDSLRTAANSLVLKIIFGIIIVSFILTGVSGYLIGGGNNYAAK
                     VNDQEISRGQFENAFNSERNRMQQQLGDQYSELAANEGYMKTLRQQVLNRLIDEALLD
                     QYARELKLGISDEQVKQAIFATPAFQVDGKFDNSRYNGILNQMGMTADQYAQALRNQL
                     TTQQLINGVAGTDFMLKGETDELAALVAQQRVVREATIDVNALAAKQPVTEQEIASYY
                     EQNKNNFMTPEQFRVSYIKLDAATMQQPVSDADIQSYYDQHQDQFTQPQRTRYSIIQT
                     KTEDEAKAVLDELNKGGDFAALAKEKSADIISARNGGDMGWLEDATIPDELKNAGLKE
                     KGQLSGVIKSSVGFLIVRLDDIQPAKVKSLDEVRDDVAAKVKHEKALDAYYALQQKVS
                     DAASNDTESLAGAEQAAGVKATQTGWFSKDNLPEELNFKPVADAIFNGGLVGENGAPG
                     INSDIITVDGDRAFVLRISEHKPEVVKPLADVQEQVKALVQHNKAEQQAKVDAEKLLV
                     DLKAGKGAEAMQAAGLKFGEPKTLSRSGRDPISQAAFALPLPAKDKPSYGMATDMQGN
                     VVLLALDEVKQGSMPEDQKKAMVQGITQNNAQIVFEALMSNLRKEAKIKIGDALEQQ"
     gene            19254..19625
                     /locus_tag="RHX21_000018"
     CDS             19254..19625
                     /locus_tag="RHX21_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HDV1985266.1"
                     /translation="MKHGIKALLITLSLACAGMSHSALAAASVAKPTAVETKAEAPAA
                     QSKAAVPAKASDEEGTRVSINNASAEELARAMNGVGLKKAQAIVSYREEYGPFKTVED
                     LKQVPGMGNSLVERNLAVLTL"
     gene            19719..20117
                     /gene="fadM"
                     /locus_tag="RHX21_000019"
     CDS             19719..20117
                     /gene="fadM"
                     /locus_tag="RHX21_000019"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain acyl-CoA thioesterase FadM"
                     /protein_id="HDV1985267.1"
                     /translation="MQTQIKVRGYHLDVYQHVNNARYLEFLEEARWDGLENSDSFQWM
                     TAHNIAFVVVNININYRRPAVLSDLLTITSQLQQLNGKSGILSQVITLEPEGQVVADA
                     LITFVCIDLKTQKALALEGELREKLEQMVK"
     gene            complement(20169..20864)
                     /gene="queC"
                     /locus_tag="RHX21_000020"
     CDS             complement(20169..20864)
                     /gene="queC"
                     /locus_tag="RHX21_000020"
                     /EC_number="6.3.4.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="HDV1985268.1"
                     /translation="MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEID
                     VARELALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNIL
                     FLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPL
                     MWIDKAETWALADYYGKLDLVRNETLTCYNGIKGDGCGHCAACNLRANGLNHYLADKP
                     TVMAAMKQKTGLR"
     gene            complement(20929..22629)
                     /locus_tag="RHX21_000021"
     CDS             complement(20929..22629)
                     /locus_tag="RHX21_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SgrR family transcriptional regulator"
                     /protein_id="HDV1985269.1"
                     /translation="MRLLNRLNQYQRLWQPSAGKPQTVTVSELAERCFCSERHVRTLL
                     RQAQEAGWLEWQAQSGRGKRGQLRFLVTPESLRNAMMEQALETGKQQDVLELAQLAPG
                     ELRTLLQPFMGGQWQNDTPTLRIPYYRPLEPLQPGFLPGRAEQHLAGQIFSGLTRFDN
                     NTQRPIGDLAHHWETSTDGLRWDFYLRSTLHWHNGDAVKASHLHQRLLMLLQLPALDQ
                     LFISVKRIEVTHPQCLTFFLHRPDYWLAHRLASYCSHLAHPQFPLIGTGPFRLTQFTA
                     ELVRLESHDYYHLRHPLLKAVEYWITPPLFEKDLGTSCRHPVQITIGKPEELQRVSQV
                     SSGISLGFCYLTLRKSPRLSLWQARKVISIIHQSGLLQTLEVGENLITASHALLPGWT
                     IPHWQVPDEVKLPKTLTLVYHLPIELHTMAERLQATLAAEGCELTIIFHNAKNWDDTT
                     LLAHADLMMGDRLIGEAPEYTLEQWLRCDPLWPHVFDAPAYAHLQSTLDAVQVMPDEE
                     NRFNALKAVFSQLMADATLTPLFNYHYRISAPPGVNGVRLTPRGWFEFTEAWLPAPSQ
                     "
     gene            22729..23547
                     /gene="cof"
                     /locus_tag="RHX21_000022"
     CDS             22729..23547
                     /gene="cof"
                     /locus_tag="RHX21_000022"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414980.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HMP-PP phosphatase"
                     /protein_id="HDV1985270.1"
                     /translation="MARLAAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGR
                     HALEMQHILGALSLDAYLITGNGTRVHSLEGELLHRDDLPADVAELVLYQQWDTRASM
                     HIFNDDGWFTGKEIPALLQAFVYSGFRYQIIDVKKMPLGSVTKICFCGDHDDLTRLQI
                     QLYEALGERAHLCFSATDCLEVLPVGCNKGAALTVLTQHLGLSLRDCMAFGDAMNDRE
                     MLGSVGSGFIMGNAMPQLRAELPHLPVIGHCRNQAVSHYLTHWLDYPHLPYSPE"
     gene            23700..24158
                     /gene="decR"
                     /locus_tag="RHX21_000023"
     CDS             23700..24158
                     /gene="decR"
                     /locus_tag="RHX21_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308528.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator DecR"
                     /protein_id="HDV1985271.1"
                     /translation="MLDKIDRKLLALLQQDCTLSLQALAEAVNLTTTPCWKRLKRLED
                     DGILIGKVALLDPEKIGLGLTAFVLIKTQHHSSEWYCRFVTVVTEMPEVLGFWRMAGE
                     YDYLMRVQVADMKRYDEFYKRLVNSVPGLSDVTSSFAMEQIKYTTSLPIE"
     gene            24188..25960
                     /locus_tag="RHX21_000024"
     CDS             24188..25960
                     /locus_tag="RHX21_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SmdA family multidrug ABC transporter
                     permease/ATP-binding protein"
                     /protein_id="HDV1985272.1"
                     /translation="MRLFAQLSWYFRREWRRYLGAVALLVIIAMLQLVPPKVVGIVVD
                     GVTEQHFTTGQILMWIATMVLIAVVVYLLRYVWRVLLFGASYQLAVELREDYYRQLSR
                     QHPEFYLRHRTGDLMARATNDVDRVVFAAGEGVLTLVDSLVMGCAVLIMMSTQISWQL
                     TLFALLPMPVMAIMIKRNGDALHERFKLAQAAFSSLNDRTQESLTSIRMIKAFGLEDR
                     QSALFAADAEDTGKKNMRVARIDARFDPTIYIAIGMANLLAIGGGSWMVVQGSLTLGQ
                     LTSFMMYLGLMIWPMLALAWMFNIVERGSAAYSRIRAMLAEAPVVNDGSEPVPEGRGE
                     LDVNIHQFTYPQTDHPALENVNFALKPGQMLGICGPTGSGKSTLLSLIQRHFDVSEGD
                     IRFHDIPLTKLQLDSWRSRLAVVSQTPFLFSDTVANNIALGCPNATQQEIEHVARLAS
                     VHDDILRLPQGYDTEVGERGVMLSGGQKQRISIARALLVNAEILILDDALSAVDGRTE
                     HQILHNLRQWGQGRTVIISAHRLSALTEASEIIVMQHGHIAQRGNHDELAQQSGWYRD
                     MYRYQQLEAALDDVPEIREEAVDA"
     gene            25953..27734
                     /locus_tag="RHX21_000025"
     CDS             25953..27734
                     /locus_tag="RHX21_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SmdB family multidrug efflux ABC transporter
                     permease/ATP-binding protein"
                     /protein_id="HDV1985273.1"
                     /translation="MRSFSQLWPTLKRLLAYGSPWRKPLGIAVLMMWVAAAAEVSGPL
                     LISYFIDNMVAKNNLPLKMVAGLAAAYVGLQLFAAGLHYAQSLLFNRAAVGVVQQLRT
                     DVMDAALRQPLSEFDTQPVGQVISRVTNDTEVIRDLYVTVVATVLRSAALVGAMLVAM
                     FSLDWRMALVAIMIFPVVLVVMVIYQRYSTPIVRRVRAYLADINDGFNEIINGMSVIQ
                     QFRQQARFGERMGEASRSHYMARMQTLRLDGFLLRPLLSLFSSLILCGLLMLFGFSAS
                     GTIEVGVLYAFISYLGRLNEPLIELTTQQAMLQQAVVAGERVFELMDGPRQQYGNDDR
                     PLQSGTIEVDNVSFAYRDDNLVLKNINLSVPSRNFVALVGHTGSGKSTLASLLMGYYP
                     LTEGEIRLDGRPLSSLSHSALRQGVAMVQQDPVVLADTFLANVTLGRDISEERVWQAL
                     ETVQLAELARSMSDGIYTPLGEQGNNLSVGQKQLLALARVLVETPQILILDEATASID
                     SGTEQAIQHALAAVREHTTLVVIAHRLSTIVDADTILVLHRGQAVEQGTHQQLLAAQG
                     RYWQMYQLQLAGEELAASVREEESLSA"
     gene            27915..28253
                     /gene="glnK"
                     /locus_tag="RHX21_000026"
     CDS             27915..28253
                     /gene="glnK"
                     /locus_tag="RHX21_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HDV1985274.1"
                     /translation="MKLVTVIIKPFKLEDVREALSSIGIQGLTVTEVKGFGRQKGHAE
                     LYRGAEYSVNFLPKVKIDVAIADDQLDEVIDIVSKAAYTGKIGDGKIFVAELQRVIRI
                     RTGEADEAAL"
     gene            28283..29569
                     /gene="amtB"
                     /locus_tag="RHX21_000027"
     CDS             28283..29569
                     /gene="amtB"
                     /locus_tag="RHX21_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter AmtB"
                     /protein_id="HDV1985275.1"
                     /translation="MKIATIKTGLASLAMLPGLVMAAPAVADKADNAFMMICTALVLF
                     MTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNINW
                     LMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTL
                     SYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLIGKRVGFGKEAFKPH
                     NLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRG
                     KPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMLKRLLRVDDPC
                     DVFGVHGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVA
                     FIGYKLADLTVGLRVPEEQEREGLDVNSHGENAYNA"
     gene            complement(29617..30477)
                     /gene="tesB"
                     /locus_tag="RHX21_000028"
     CDS             complement(29617..30477)
                     /gene="tesB"
                     /locus_tag="RHX21_000028"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase II"
                     /protein_id="HDV1985276.1"
                     /translation="MSQALKNLLTLLNLEKIEEGLFRGQSEDLGLRQVFGGQVVGQAL
                     YAAKETVPEERLVHSFHSYFLRPGDSKKPIIYDVETLRDGNSFSARRVAAIQNGKPIF
                     YMTASFQAPEAGFEHQKTMPSAPAPDGLPSETQIAQSLAHLLPPVLKDKFICDRPLEV
                     RPVEFHNPLKGHVAEPHRQVWIRANGSVPDDLRVHQYLLGYASDLNFLPVALQPHGIG
                     FLEPGIQIATIDHSMWFHRPFNLNEWLLYSVESTSASSARGFVRGEFYTQDGVLVAST
                     VQEGVMRNHN"
     gene            30695..31267
                     /locus_tag="RHX21_000029"
     CDS             30695..31267
                     /locus_tag="RHX21_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaY family lipoprotein"
                     /protein_id="HDV1985277.1"
                     /translation="MKLVHMASGLAVAIALAACADKSADIQTPAPAANTSISATQQPA
                     IQQPNVSGTVWIRQKVALPPDAVLTVTLSDASLADAPSKVLAQKAVRTEGKQSPFSFV
                     LPFNPADVQPNARILLSAAITVNDKLVFITDTVQPVINQGGTKADLTLVPVQQTAVPV
                     QASGGATTTVPSTSPTQVNPSSAVPAPTQY"
     gene            complement(31298..31609)
                     /locus_tag="RHX21_000030"
     CDS             complement(31298..31609)
                     /locus_tag="RHX21_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706349.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MGMT family protein"
                     /protein_id="HDV1985278.1"
                     /translation="MEKEDSFPQRVWQIVAAIPEGYVTTYGDVAKLAGSPRAARQVGG
                     VLKRLPEGSTLPWHRVVNRHGTISLTGPDLQRQRQALLAEGVMVSGSGQIDLQRYRWN
                     Y"
     gene            31772..31868
                     /gene="ffs"
                     /locus_tag="RHX21_000031"
     ncRNA           31772..31868
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="RHX21_000031"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            31988..32341
                     /locus_tag="RHX21_000032"
     CDS             31988..32341
                     /locus_tag="RHX21_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1428 domain-containing protein"
                     /protein_id="HDV1985279.1"
                     /translation="MKYVDGFVVAVPADKKDAYREMAAKAAPLFKEFGALRIVECWAS
                     DVPDGKVTDFRMAVKAEENEEVVFSWIEYPSKEVRDAANQKMMSDPRMKEFGESMPFD
                     GKRMIYGGFESIIDE"
     gene            complement(32383..33933)
                     /gene="pdeB"
                     /locus_tag="RHX21_000033"
     CDS             complement(32383..33933)
                     /gene="pdeB"
                     /locus_tag="RHX21_000033"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308537.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase
                     PdeB"
                     /protein_id="HDV1985280.1"
                     /translation="MRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELDTY
                     SSRVAIRANKVATQGKDALQELERWQGAACSEAHLMEMRRVSYSYRYIQEVVYIDNNV
                     PQCSSLEHESPPDTFPEPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPAS
                     FIDVIPYSSWQIDAAIIGNAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILP
                     FPEMNISIITWASTKMLQKGWHRQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQ
                     DAIENRDICVHYQPIVSLANGKIVGAEALARWPQTDGSWLSPDSFIPLAQQTGLSEPL
                     TLLIIRSVFEDMGDWLRQHPQQHISINLESTVLTSEKIPQLLREMINHYQVNPRQIAL
                     ELTEREFADPKTSAPIISRYREAGHEIYLDDFGTGYSSLSYLQDLDVDILKIDKSFVD
                     ALEYKNVTPHIIEMAKTLKLKMVAEGIETSKQEEWLRQHGVHYGQGWLYSKALPKEDF
                     LRWAEQHL"
     gene            complement(34097..34567)
                     /locus_tag="RHX21_000034"
     CDS             complement(34097..34567)
                     /locus_tag="RHX21_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308538.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaC family protein"
                     /protein_id="HDV1985281.1"
                     /translation="MTEIQRLLTETIESLNTREKRDNKPRFSISFIRKHPGLFIGMYV
                     AFFATLAVMLQSETLSGSVWLLVVLFILLNGFFFFDVYPRYRYEDIDVLDFRVCYNGE
                     WYNTRFVPAALVEAILNSPRVADVHKEQLQKMIVRKGELSFYDIFTLARAESTS"
     gene            complement(34683..35234)
                     /gene="maa"
                     /locus_tag="RHX21_000035"
     CDS             complement(34683..35234)
                     /gene="maa"
                     /locus_tag="RHX21_000035"
                     /EC_number="2.3.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose O-acetyltransferase"
                     /protein_id="HDV1985282.1"
                     /translation="MSTEKEKMIAGELYRSADETLSRDRLRARQLIHRYNHSLAEEHT
                     LRQQILADLFGQVTEAYIEPTFRCDYGYNIFLGNNFFANFDCVMLDVCPIRIGDNCML
                     APGVHIYTATHPIDPVARNSGAELGKPVTIGNNVWIGGRAVINPGVTIGDNVVVASGA
                     VVTKDVPNNVVVGGNPARIIKKL"
     gene            complement(35406..35624)
                     /gene="hha"
                     /locus_tag="RHX21_000036"
     CDS             complement(35406..35624)
                     /gene="hha"
                     /locus_tag="RHX21_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="HDV1985283.1"
                     /translation="MSEKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFY
                     SAADHRLAELTMNKLYDKIPSSVWKFIR"
     gene            complement(35650..36024)
                     /gene="tomB"
                     /locus_tag="RHX21_000037"
     CDS             complement(35650..36024)
                     /gene="tomB"
                     /locus_tag="RHX21_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hha toxicity modulator TomB"
                     /protein_id="HDV1985284.1"
                     /translation="MDEYSPKRHDIAQLKFLCETLYHDCLANLEESNHGWVNDPTSAI
                     NLQLNELIEHIATFALNYKIKYNEDNKLIEQIDEYLDDTFMLFSSYGINMQDLQKWRK
                     SGNRLFRCFVNATKENPASLSC"
     gene            complement(36570..39719)
                     /locus_tag="RHX21_000038"
     CDS             complement(36570..39719)
                     /locus_tag="RHX21_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="HDV1985285.1"
                     /translation="MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVT
                     ISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADI
                     AQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA
                     NMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQ
                     LGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYD
                     IIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVK
                     ISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLS
                     AVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEG
                     KKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPD
                     EDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNT
                     GIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDF
                     ELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALG
                     VSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQM
                     VPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVG
                     YDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALL
                     AATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRL
                     RPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVR
                     RRFSRKNEDIEHSHTVDHH"
     gene            complement(39742..40935)
                     /gene="acrA"
                     /locus_tag="RHX21_000039"
     CDS             complement(39742..40935)
                     /gene="acrA"
                     /locus_tag="RHX21_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter periplasmic
                     adaptor subunit AcrA"
                     /protein_id="HDV1985286.1"
                     /translation="MNKNRGFTPLAVVLMLSGSLALTGCDDKQAQQGGQQMPAVGVVT
                     VKTEPLQITTELPGRTSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQ
                     ATYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAA
                     KAAVETARINLAYTKVTSPISGRIGKSNVTEGALVQNGQATALATVQQLDPIYVDVTQ
                     SSNDFLRLKQELANGTLKQENGKAKVSLITSDGIKFPQDGTLEFSDVTVDQTTGSITL
                     RAIFPNPDHTLLPGMFVRARLEEGLNPNAILVPQQGVTRTPRGDATVLVVGADDKVET
                     RPIVASQAIGDKWLVTEGLKAGDRVVISGLQKVRPGVQVKAQEVTADNNQQAASGAQP
                     EQSKS"
     gene            41077..41724
                     /gene="acrR"
                     /locus_tag="RHX21_000040"
     CDS             41077..41724
                     /gene="acrR"
                     /locus_tag="RHX21_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter transcriptional
                     repressor AcrR"
                     /protein_id="HDV1985287.1"
                     /translation="MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVT
                     RGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVT
                     EERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMT
                     RRAAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE"
     gene            41852..45214
                     /gene="mscK"
                     /locus_tag="RHX21_000041"
     CDS             41852..45214
                     /gene="mscK"
                     /locus_tag="RHX21_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel MscK"
                     /protein_id="HDV1985288.1"
                     /translation="MTMFQYYKRSRHFVFSAFIAFVFVLLCQNTAFARASSNGDLPTK
                     ADLQAQLDSLNKQKDLSAQDKLVQQDLTDTLATLDKIDRIKEETVQLRQKVAEAPEKM
                     RQATAALTALSDVDNDEETRKILSTLSLRQLETRVAQALDDLQNAQNDLASYNSQLVS
                     LQTQPERVQNAMYNASQQLQQIRSRLDGTDVGETALRPSQKVLMQAQQALLNAEIDQQ
                     RKSLEGNTVLQDTLQKQRDYVTANSARLEHQLQLLQEAVNSKRLTLTEKTAQEAVSPD
                     EAARIQANPLVKQELEINQQLSQRLITATENGNQLMQQNIKVKNWLERALQSERNIKE
                     QIAVLKGSLLLSRILYQQQQTLPSADELENMTNRIADLRLEQFEVNQQRDALFQSDAF
                     VNKLEEGHTNEVNSEVHDALLQVVDMRRELLDQLNKQLGNQLMMAINLQINQQQLMSV
                     SKNLKSILTQQIFWVNSNRPMDWDWIKAFPQSLKDEFKSMKITVNWEKAWPAVFIAFL
                     AGLPLLLIAGLIHWRLGWLKAYQQKLASAVGSLRNDSQLNTPKAILIDLIRALPVCLI
                     ILAVGLILLTMQLNISELLWSFSKKLAIFWLVFGLCWKVLEKNGVAVRHFGMPEQQTS
                     HWRRQIVRISLALLPIHFWSVVAELSPLHLMDDVLGQAMIFFNLLLIAFLVWPMCRES
                     WRDKESHTMRLVTITVLSIIPIALMVLTATGYFYTTLRLSGRWIETVYLVIIWNLLYQ
                     TVLRGLSVAARRIAWRRALARRQNLVKEGAEGAEPPEEPTIALEQVNQQTLRITMLLM
                     FALFGVMFWAIWSDLITVFSYLDSITLWHYNGTEAGAAVVKNVTMGSLLFAIIASMVA
                     WALIRNLPGLLEVLVLSRLNMRQGASYAITTILNYIIIAVGAMTVFGSLGVSWDKLQW
                     LAAALSVGLGFGLQEIFGNFVSGLIILFERPVRIGDTVTIGSFSGTVSKIRIRATTIT
                     DFDRKEVIIPNKAFVTERLINWSLTDTTTRLVIRLGVAYGSDLEKVRKVLLKAATEHP
                     RVMHEPMPEVFFTAFGASTLDHELRLYVRELRDRSRTVDELNRTIDQLCRENDINIAF
                     NQLEVHLHNEKGDEVTEVKRDYKGDDPTPAVG"
     gene            complement(45426..45587)
                     /gene="rsmS"
                     /locus_tag="RHX21_000042"
     CDS             complement(45426..45587)
                     /gene="rsmS"
                     /locus_tag="RHX21_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pleiotropic regulatory protein RsmS"
                     /protein_id="HDV1985289.1"
                     /translation="MSLENAPDDVKLAVDLIVLLEENQIPARTVLRALDIVKRDYEKK
                     LTRDDEAEK"
     gene            complement(45601..46128)
                     /gene="priC"
                     /locus_tag="RHX21_000043"
     CDS             complement(45601..46128)
                     /gene="priC"
                     /locus_tag="RHX21_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N''"
                     /protein_id="HDV1985290.1"
                     /translation="MKTALLLEKLEGQLATLRQRCAPVAQFATLSARFDRHLFQTRAT
                     TLQACLDEAGDNLAALRHAVEQQQLPQVAWLAEHLAAQLEAIAREASAWSLREWDSAP
                     PKIARWQRKRIQHQDFERRLREMVAERRARLARVTDLVEQQTLHREVEAYEARLARCR
                     HALEKIENRLARLTR"
     gene            46198..46575
                     /locus_tag="RHX21_000044"
     CDS             46198..46575
                     /locus_tag="RHX21_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF454 family protein"
                     /protein_id="HDV1985291.1"
                     /translation="MQRIILIIIGWLAVVLGTLGVVLPVLPTTPFILLAAWCFARSSP
                     RFHAWLLYRSWFGSYLRFWQKHHAMPRGVKPRAILLILLTFAISLWFVQMPWVRIMLL
                     VILACLLFYMWRIPVIDEKQEKH"
     gene            46728..47279
                     /gene="apt"
                     /locus_tag="RHX21_000045"
     CDS             46728..47279
                     /gene="apt"
                     /locus_tag="RHX21_000045"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HDV1985292.1"
                     /translation="MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALS
                     IDLLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISETYDL
                     EYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFD
                     LGGEQRLEKQGITSYSLVPFPGH"
     gene            47408..49339
                     /gene="dnaX"
                     /locus_tag="RHX21_000046"
     CDS             47408..49339
                     /gene="dnaX"
                     /locus_tag="RHX21_000046"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HDV1985293.1"
                     /translation="MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFS
                     GTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRTKVE
                     DTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ
                     KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDAL
                     SLTDQAIASGDGQVSTQAVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGI
                     EWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTIPPTDIQLYYQTLLI
                     GRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEPEVPRQSFAPVAPTAVMTPTQVPPQ
                     PQSAPQQAPTVPLPETTSQVLAARQQLQRVQGATKAKKSEPAAATRARPVNNAALERL
                     ASVTDRVQARPVPSALEKAPAKKEAYRWKATTPVMQQKEVVATPKALKKALEHEKTPE
                     LAAKLAAEAIERDAWAAQVSQLSLPKLVEQVALNAWKEESDNAVCLHLRSSQRHLNNR
                     GAQQKLAEALSTLKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARESIIADNNI
                     QTLRRFFDAELDEESIRPI"
     misc_feature    48672..48736
                     /gene="dnaX"
                     /locus_tag="RHX21_000046"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00382"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="DnaX frameshifting element; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00382"
     gene            49392..49721
                     /locus_tag="RHX21_000047"
     CDS             49392..49721
                     /locus_tag="RHX21_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001364632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HDV1985294.1"
                     /translation="MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKV
                     TINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSSGMQLP
                     PGFKMPF"
     gene            49721..50326
                     /gene="recR"
                     /locus_tag="RHX21_000048"
     CDS             49721..50326
                     /gene="recR"
                     /locus_tag="RHX21_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HDV1985295.1"
                     /translation="MQTSPLLTQLMEALRCLPGVGPKSAQRMAFTLLQRDRSGGMRLA
                     QALTRAMSEIGHCADCRTFTEQEVCNICSNPRRQENGQICVVESPADIYAIEQTGQFS
                     GRYFVLMGHLSPLDGIGPDDIGLDRLEQRLAEEKITEVILATNPTVEGEATANYIAEL
                     CAQYDVEASRIAHGVPVGGELEMVDGTTLSHSLAGRHKIRF"
     gene            50436..52310
                     /gene="htpG"
                     /locus_tag="RHX21_000049"
     CDS             50436..52310
                     /gene="htpG"
                     /locus_tag="RHX21_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003903109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HDV1985296.1"
                     /translation="MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAAD
                     KLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGT
                     KSFLESLGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEG
                     EYTVADITKEDRGTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDG
                     ETVISWEKINKAQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTS
                     LLYIPSQAPWDMWNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNV
                     SREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFAN
                     QEAIAKLLRFASTYTDSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELL
                     RKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKAL
                     TPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEVKY
                     IFELNPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLVS
                     "
     gene            52491..53135
                     /gene="adk"
                     /locus_tag="RHX21_000050"
     CDS             52491..53135
                     /gene="adk"
                     /locus_tag="RHX21_000050"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007706188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HDV1985297.1"
                     /translation="MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSE
                     LGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGIN
                     VDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQ
                     EETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG"
     gene            53371..54333
                     /gene="hemH"
                     /locus_tag="RHX21_000051"
     CDS             53371..54333
                     /gene="hemH"
                     /locus_tag="RHX21_000051"
                     /EC_number="4.98.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HDV1985298.1"
                     /translation="MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTSRLL
                     WWPLLRGVILPLRSPRVAKLYASVWMEDGSPLMVYSRQQQQALAQRLPDTPVALGMSY
                     GSPSLESAVDELLAEHVDHIVVLPLYPQFSCSTVGAVWDELARILARKRSIPGISFIR
                     DYADNHDYINALANSVRASFAKHGEPDLLLLSYHGIPQRYADEGDDYPQRCRTTTREL
                     ASALGMAPEKVMMTFQSRFGREPWLMPYTDETLKMLGEKGVGHIQVMCPGFAADCLET
                     LEEIAEQNREVFLGAGGKKYEYIPALNATPEHIEMMANLVAAYR"
     gene            complement(54330..55289)
                     /gene="aes"
                     /locus_tag="RHX21_000052"
     CDS             complement(54330..55289)
                     /gene="aes"
                     /locus_tag="RHX21_000052"
                     /EC_number="3.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl esterase"
                     /protein_id="HDV1985299.1"
                     /translation="MKPENKLPVLDLISAEMKTVVNTLQPDLPSWPATGTIAEQRQYY
                     TLERRFWNAGAPEMATRAYMVPTKYGQVETRLFCPQPDSPATLFYLHGGGFILGNLDT
                     HDRIMRLLASYSQCTVIGIDYPLSPEARFPQAIEEIVAACCYFHQQAEDYQINMSRIG
                     FAGDSAGAMLALASALWLRDKQIDCGKIAGVLLWYGLYGLRDSVTRRLLGGVWDGLTQ
                     QDLQMYEEAYLSNDADRESPYYCLFNNDLTREVPPCFIAGAEFDPLLDDSRLLYQTLA
                     AHQQPCEFKLYPGTLHAFLHYSRMMKTADEALRDGAQFFTAQL"
     gene            55441..56745
                     /gene="gsk"
                     /locus_tag="RHX21_000053"
     CDS             55441..56745
                     /gene="gsk"
                     /locus_tag="RHX21_000053"
                     /EC_number="2.7.1.73"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inosine/guanosine kinase"
                     /protein_id="HDV1985300.1"
                     /translation="MKFPGKRKSKHYFPVNARDPLLQQFQPENETSAAWVVGIDQTLV
                     DIEAKVDDEFIERYGLSAGHSLVIEDDVAEALYQELKQKNLITHQFAGGTIGNTMHNY
                     SVLADDRSVLLGVMCSNIEIGSYAYRYLCNTSSRTDLNYLQGVDGPIGRCFTLIGESG
                     ERTFAISPGHMNQLRAESIPEDVIAGASALVLTSYLVRCKPGEPMPEATMKAIEYAKK
                     YNVPVVLTLGTKFVIAENPQWWQQFLKDHVSILAMNEDEAEALTGESDPLLASDKALD
                     WVDLVLCTAGPIGLYMAGFTEDEAKRKTQHPLLPGAIAEFNQYEFSRAMRHKDCQNPL
                     RVYSHIAPYMGGPEKIMNTNGAGDGALAALLHDITANSYHRSNVPNSSKHKFTWLTYS
                     SLAQVCKYANRVSYQVLNQHSPRLTRGLPEREDSLEESYWDR"
     gene            complement(56828..58504)
                     /locus_tag="RHX21_000054"
     CDS             complement(56828..58504)
                     /locus_tag="RHX21_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Kef family K(+) transporter"
                     /protein_id="HDV1985301.1"
                     /translation="MHHATPLITTIVGGLVLAFILGMLANKLRISPLVGYLLAGVLAG
                     PFTPGFVADTKLAPELAELGVILLMFGVGLHFSLKDLMAVKAIAIPGAIAQIAVATLL
                     GMALSAVLGWSLMTGIVFGLCLSTASTVVLLRALEERQLIDSQRGQIAIGWLIVEDLV
                     MVLTLVLLPAVAGMMEQGDVGFATLAVDMGITIGKVIAFIAIMMLVGRRLVPWIMARS
                     AATGSRELFTLSVLALALGIAFGAVELFDVSFALGAFFAGMVLNESELSHRAAHDTLP
                     LRDAFAVLFFVSVGMLFDPLILIQQPLAVLATLAIILFGKSLAAFFLVRLFGHSQRTA
                     LTIAASLAQIGEFAFILAGLGMALNLLPQAGQNLVLAGAILSIMLNPVLFALLEKYLA
                     KTETLEEQTLEEAIEEEKQIPVDICNHALLVGYGRVGSLLGEKLLASDIPLVVIETSR
                     TRVDELRERGVRAVLGNAANEEIMQLAHLECAKWLILTIPNGYEAGEIVASARAKNPD
                     IEIIARAHYDDEVTYITERGANQVVMGEREIARTMLELLETPPAGEVVTG"
     gene            complement(58742..59962)
                     /gene="fsr"
                     /locus_tag="RHX21_000055"
     CDS             complement(58742..59962)
                     /gene="fsr"
                     /locus_tag="RHX21_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fosmidomycin MFS transporter"
                     /protein_id="HDV1985302.1"
                     /translation="MAMSEQPQPVAGAAASTTKARTSFGILGAISLSHLLNDMIQSLI
                     LAIYPLLQSEFSLTFMQIGMITLTFQLASSLLQPVVGYWTDKYPMPWSLPIGMCFTLS
                     GLVLLALAGSFGAVLLAAALVGTGSSVFHPESSRVARMASGGRHGLAQSIFQVGGNFG
                     SSLGPLLAAVIIAPYGKGNVAWFVLAALLAIVVLAQISRWYSAQHRMNKGKPKATIIN
                     PLPRNKVVLAVSILLILIFSKYFYMASISSYYTFYLMQKFGLSIQNAQLHLFAFLFAV
                     AAGTVIGGPVGDKIGRKYVIWGSILGVAPFTLILPYASLHWTGVLTVIIGFILASAFS
                     AILVYAQELLPGRIGMVSGLFFGFAFGMGGLGAAVLGLIADHTSIELVYKICAFLPLL
                     GMLTIFLPDNRHKD"
     gene            60180..61832
                     /gene="ushA"
                     /locus_tag="RHX21_000056"
     CDS             60180..61832
                     /gene="ushA"
                     /locus_tag="RHX21_000056"
                     /EC_number="3.1.3.5"
                     /EC_number="3.6.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-sugar
                     hydrolase/5'-nucleotidase"
                     /protein_id="HDV1985303.1"
                     /translation="MKLLQRGVALALLTTFTLASETALAYEQDKTYKITVLHTNDHHG
                     HFWRNEYGEYGLAAQKTLVDGIRKEVAAEGGSVLLLSGGDINTGVPESDLQDAEPDFR
                     GMNLVGYDAMAIGNHEFDNPLTVLRQQEKWAKFPLLSANIYQKSTGERLFKPWALFKR
                     QDLKIAVIGLTTDDTAKIGNPEYFTDVEFRKPADEAKLVIQELQQTEKPDIIIAATHM
                     GHYDNGEHGSNAPGDVEMARALPAGSLAMIVGGHSQDPVCMAAENKKQVDYVPGTPCK
                     PDQQNGIWIVQAHEWGKYVGRADFEFRNGEMKMVNYQLIPVNLKKKVTWEDGKSERVL
                     YTPEIAENQQMISLLSPFQNKGKAQLEVKIGETNGRLEGDRDKVRFVQTNMGRLILAA
                     QMDRTGADFAVMSGGGIRDSIEAGDISYKNVLKVQPFGNVVVYADMTGKEVIDYLTAV
                     AQMKPDSGAYPQFANVSFVAKDGKLNDLKIKGEPVDPAKTYRMATLNFNATGGDGYPR
                     LDNKPGYVNTGFIDAEVLKAYIQKSSPLDVSVYEPKGEVSWQ"
     gene            complement(61869..62348)
                     /gene="ybaK"
                     /locus_tag="RHX21_000057"
     CDS             complement(61869..62348)
                     /gene="ybaK"
                     /locus_tag="RHX21_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK"
                     /protein_id="HDV1985304.1"
                     /translation="MTPAVKLLEKNKISFQIHTYEHDPAETNFGDEVVKKLGLNPDQV
                     YKTLLVAVNGDMKHLAVAVTPVAGQLDLKKVAKALGAKKVEMADPMVAQRSTGYLVGG
                     ISPLGQKKRLPTIIDAPAQEFATIYVSGGKRGLDIELAAGDLAKILDAKFADIARRD"
     gene            complement(62552..63346)
                     /locus_tag="RHX21_000058"
     CDS             complement(62552..63346)
                     /locus_tag="RHX21_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraB/GumN family protein"
                     /protein_id="HDV1985305.1"
                     /translation="MDLLYRVKTLWAALRGNHYTWPAIDITLPGNRHFHLIGSIHMGS
                     HDMAPLPTRLLKKLKNADALIVEADVSTSDTPFANLPTCEALEERINEEQLQNLQHIS
                     QEMGISPSLFSTQPLWQIAMVLQATQAQKLGLRAEYGIDYQLLQAAKQQHKPVIELEG
                     AENQITMLLQLPDKGLALLDDTLTHWHTNARLLQQMMSWWLNAPPQNNDITLPNTFSQ
                     SLYDVLMHQRNLAWRDKLRAMPPGRYVVAVGALHLYGEGNLPQMLR"
     gene            63484..63825
                     /locus_tag="RHX21_000059"
     CDS             63484..63825
                     /locus_tag="RHX21_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415016.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HigA family addiction module antidote protein"
                     /protein_id="HDV1985306.1"
                     /translation="MKQATRKPTTPGDILLYEYLEPLDLKINELAELLHVHRNSVSAL
                     INNNRKLTTEMAFRLAKVFDTTVDFRLNLQAAVDLWEVENNMRTQEELGRIETVAEYL
                     ARREERAKKVA"
     gene            complement(63939..66443)
                     /gene="copA"
                     /locus_tag="RHX21_000060"
     CDS             complement(63939..66443)
                     /gene="copA"
                     /locus_tag="RHX21_000060"
                     /EC_number="7.2.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-exporting P-type ATPase CopA"
                     /protein_id="HDV1985307.1"
                     /translation="MSQIIDLTLDGLSCGHCVKRVKESLEQRPDVEQADVSITEAHVT
                     GTASAEQLIETIKQAGYDASVSHPKAKPLAESSIPSEALTAVSEALPAATADDDDSQQ
                     LLLSGMSCASCVTRVQNALQSVPGVTQARVNLAERTALVMGSASPQDLVQAVEKAGYG
                     AEAIEDDAKRRERQQETAVATMKRFRWQAIVALAVGIPVMVWGMIGDNMMVTADNRSL
                     WLVIGLITLAVMVFAGGHFYRSAWKSLLNGAATMDTLVALGTGVAWLYSMSVNLWPQW
                     FPMEARHLYYEASAMIIGLINLGHMLEARARQRSSKALEKLLDLTPPTARLVTDEGEK
                     SVPLAEVQPGMLLRLTTGDRVPVDGEITQGEAWLDEAMLTGEPIPQQKGEGESVHAGT
                     VVQDGSVLFRASAVGSHTTLSRIIRMVRQAQSSKPEIGQLADKISAVFVPVVVVIALV
                     SAAIWYFFGPAPQIVYTLVIATTVLIIACPCALGLATPMSIISGVGRAAEFGVLVRDA
                     DALQRASTLDTVVFDKTGTLTEGKPQVVAVKTFADVDEAQALRLAAALEQGSSHPLAR
                     AILDKAGDMQLPQVNGFRTLRGLGVSGEAEGHALLLGNQALLNEQQVGTKAIEAEITA
                     QASQGATPVLLAIDGKAVALLAVRDPLRSDSVAALQRLHKAGYRLVMLTGDNPTTANA
                     IAKEAGIDEVIAGVLPDGKAEAIKRLQSEGRQVAMVGDGINDAPALAQADVGIAMGGG
                     SDVAIETAAITLMRHSLMGVADALAISRATLRNMKQNLLGAFIYNSIGIPVAAGILWP
                     FTGTLLNPVVAGAAMALSSITVVSNANRLLRFKPKE"
     gene            66705..67637
                     /gene="glsA"
                     /locus_tag="RHX21_000061"
     CDS             66705..67637
                     /gene="glsA"
                     /locus_tag="RHX21_000061"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HDV1985308.1"
                     /translation="MLDANKLQQAVDQAYTQFHSLNGGQNADYIPFLANVPGQLAAVA
                     IVTCDGKVYSAGDSDYRFALESISKVCTLALALEDVGPQAVQDKIGADPTGLPFNSVI
                     ALELHGGKPLSPLVNAGAIATTSLINAENVEQRWQRILHIQQQLAGEQVALSDEVNQS
                     EQTTNFHNRAIAWLLYSAGYLYCDAMEACDVYTRQCSTLLNTVELATLGATLAAGGVN
                     PLTHKRVLQADNVPYILAEMMMEGLYGRSGEWAYRVGLPGKSGVGGGILAVVPGVMGI
                     AAFSPPLDEEGNSVRGQKMVASVAKQLGYNVFKG"
     gene            67640..68932
                     /locus_tag="RHX21_000062"
     CDS             67640..68932
                     /locus_tag="RHX21_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDV1985309.1"
                     /translation="MMNTEGNNGNKPLGLWNVVSIGIGAMVGAGIFALLGQAALLMEA
                     STWVAFAFGGIVAMFSGYAYARLGASYPSNGGIIDFFRRGLGNGVFSLALSLLYLLTL
                     AVSIAMVARAFGAYAVQFLHEGSQEEHLILLYALGIIAVMTLFNSLSNHAVGRLEVIL
                     VGIKMMILLLLIIAGVWSLQPAHISVSAPPSSGAFFSCIGITFLAYAGFGMMANAADK
                     VKDPQVIMPRAFLVAIGVTTLLYISLALVLLSDVSALELEKYADTAVAQAASPLLGHV
                     GYVIVVIGALLATASAINANLFAVFNIMDNMGSERELPKLMNKSLWRQSTWGNIIVVV
                     LIMLMTAALNLGSLASVASATFLICYLAVFVVAIRLRHDIHASLPILIVGTLVMLLVI
                     VGFIYSLWSQGSRALIWIIGSLLLSLIVAMVMKRNKTV"
     gene            69057..69464
                     /gene="cueR"
                     /locus_tag="RHX21_000063"
     CDS             69057..69464
                     /gene="cueR"
                     /locus_tag="RHX21_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(I)-responsive transcriptional regulator"
                     /protein_id="HDV1985310.1"
                     /translation="MNISDVAKITGLTSKAIRFYEEKGLVTPPMRSENGYRTYTQQHL
                     NELTLLRQARQVGFNLEESGELVNLFNDPQRHSADVKRRTLEKVAEIERHIEELQSMR
                     DQLLALANACPGDDSADCPIIENLSGCCHHRAG"
     gene            complement(69465..69923)
                     /locus_tag="RHX21_000064"
     CDS             complement(69465..69923)
                     /locus_tag="RHX21_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415021.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HDV1985311.1"
                     /translation="MMELMVVHPHIFWLSLGGLLLAAEMLGGNGYLLWSGVAAVITGL
                     VVWLVPLGWEWQGVMFAILTLLAAWLWWKWLSRRVREQKHSDSHLNQRGQQLIGRRFV
                     LESPLVNGRGHMRVGDSSWPVSASEDLGAGTHVEVIAIEGITLHIRAVSS"
     gene            complement(69920..70837)
                     /locus_tag="RHX21_000065"
     CDS             complement(69920..70837)
                     /locus_tag="RHX21_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HDV1985312.1"
                     /translation="MLIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPG
                     LSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNANVTIDAVCFIQVIDAPRAAYEVS
                     NLELAIINLTMTNIRTVLGSMELDEMLSQRDSINSRLLRIVDEATNPWGIKVTRIEIR
                     DVRPPAELISSMNAQMKAERTKRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSA
                     FLQAEARERSAEAEARATKMVSEAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVM
                     MPLEASSLMGSIAGIAELVKDSANKRTQP"
     gene            70983..71660
                     /gene="fetA"
                     /locus_tag="RHX21_000066"
     CDS             70983..71660
                     /gene="fetA"
                     /locus_tag="RHX21_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter ATP-binding protein FetA"
                     /protein_id="HDV1985313.1"
                     /translation="MQENSPLLQLQNVGYLAGDAKILNNINFSLRAGEFKLITGPSGC
                     GKSTLLKIVASLISPTSGTLLFEGEDVSTLKPEIYRQQVSYCAQTPTLFGDTVYDNLI
                     FPWQIRNQQPDPAIFLDFLERFALPDSILTKNIAELSGGEKQRISLIRNLQFMPKVLL
                     LDEITSALDESNKHNVNEMIHRYVREQNIAVLWVTHDKDEINHADKVITLQPHAGEMQ
                     EARYELA"
     gene            71647..72426
                     /gene="fetB"
                     /locus_tag="RHX21_000067"
     CDS             71647..72426
                     /gene="fetB"
                     /locus_tag="RHX21_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308581.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron export ABC transporter permease subunit
                     FetB"
                     /protein_id="HDV1985314.1"
                     /translation="MNSHNITNESLALALMLVVVAILISHKEKLALEKDIFWSVGRAI
                     IQLIIVGYVLKYIFSVDDASLTLLMVLFICFNAAWNAQKRSKYIAKAFISSFIAITVG
                     AGITLAVLILSGSIEFIPMQVIPIAGMIAGNAMVAVGLCYNNLGQRVISEQQQIQEKL
                     SLGATPKQASAILIRDSIRAALIPTVDSAKTVGLVSLPGMMSGLIFAGIDPVKAIKYQ
                     IMVTFMLLSTASLSTIIACYLTYRKFYNSRHQLVVTQLKKK"
     gene            complement(72489..73343)
                     /gene="cnoX"
                     /locus_tag="RHX21_000068"
     CDS             complement(72489..73343)
                     /gene="cnoX"
                     /locus_tag="RHX21_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308582.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperedoxin"
                     /protein_id="HDV1985315.1"
                     /translation="MSVENIVNINESNLQQVLEQSMTTPVLFYFWSERSQHCLQLTPI
                     LESLAAQYNGQFILAKLDCDAEQMIAAQFGLRAIPTVYLFQNGQPVDGFQGPQPEEAI
                     RALLDKVLPREEELKAQQAMQLMQEGNYTDALPLLKDAWQLSNQNGEIGLLLAETLIA
                     LNRSEDAEAVLKTIPLQDQDTRYQGLVAQIELLKQAADTPEIQQLQQQVAENPEDAAL
                     ATQLALQLHQVGRNEEALELLFGHLRKDLTAADGQTRKTFQEILAALGTGDALASKYR
                     RQLYALLY"
     gene            complement(73404..74213)
                     /gene="ybbO"
                     /locus_tag="RHX21_000069"
     CDS             complement(73404..74213)
                     /gene="ybbO"
                     /locus_tag="RHX21_000069"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(+)-dependent aldehyde reductase"
                     /protein_id="HDV1985316.1"
                     /translation="MTHKATEILTGKVMQKSVLITGCSSGIGLESALELKRQGFHVLA
                     GCRKPDDVERMNSMGFTGVLIDLDSPESVDRAADEVIALTDNCLYGIFNNAGFGMYGP
                     LSTISRAQMEQQFSANFFGAHQLTIRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYA
                     ASKYALEAWSDALRMELRHSGIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARF
                     TLGPEAVVDKVRHAFISEKPKMRYPVTLVTWAVMVLKRLLPGRVMDKILQG"
     gene            complement(74203..74826)
                     /gene="tesA"
                     /locus_tag="RHX21_000070"
     CDS             complement(74203..74826)
                     /gene="tesA"
                     /locus_tag="RHX21_000070"
                     /EC_number="3.1.1.5"
                     /EC_number="3.1.2.14"
                     /EC_number="3.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional acyl-CoA thioesterase I/protease
                     I/lysophospholipase L1"
                     /protein_id="HDV1985317.1"
                     /translation="MNFNNVFRWHLPFLFLVLLTFRAAAADTLLILGDSLSAGYRMSA
                     SAAWPALLNDKWQSKTSVVNASISGDTSQQGLARLPALLKQHQPRWVLVELGGNDGLR
                     GFQPQQTEQTLRQILQDVKAANAEPLLMQIRLPANYGRRYNEAFSAIYPKLAKEFDVP
                     LLPFFMEEVYLKPQWMQDDGIHPNRDAQPFIADWMAKQLQPLVNHDS"
     gene            74797..75483
                     /locus_tag="RHX21_000071"
     CDS             74797..75483
                     /locus_tag="RHX21_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDV1985318.1"
                     /translation="MPAENIVEVHHLKKSVGQGEHELSILTGVELVVKRGETIALVGE
                     SGSGKSTLLAILAGLDDGSSGEVSLVGQPLHNMDEEARAKLRAKHVGFVFQSFMLIPT
                     LNALENVELPALLRGESSAESRNGAKALLEQLGLGKRLDHLPTQLSGGEQQRVALARA
                     FNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLIMVTHDLQLAARCDRCLR
                     LVNGQLQEEA"
     gene            75480..77894
                     /locus_tag="RHX21_000072"
     CDS             75480..77894
                     /locus_tag="RHX21_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV1985319.1"
                     /translation="MIARWFWREWRSPSLLIVWLALSLAVACVLALGNISDRMEKGLS
                     QQSREFMAGDRALRSSREVPQAWLEEAQKRGLKVGKQLTFATMTFAGDTPQLANVKAV
                     DDIYPMYGDLQTNPPGLKPQAGSVLLAPRLMALLNLKTGDTIDVGDATLRIAGEVIQE
                     PDSGFNPFQMAPRLMMNLADVDKTGAVQPGSRVTWRYKFGGNENQLDGYEKWLLPQLK
                     PEQRWYGLEQDEGALGRSMERSQQFLLLSALLTLLLAVAAVAVAMNHYCRSRYDLVAI
                     LKTLGAGRAQLRKLIVGQWLMVLTLSAVTGGTIGLLFENVLMVLLKPVLPAALPPASL
                     WPWLWALGTMTVISLLVGLRPYRLLLATQPLRVLRNDVVANVWPLKFYLPIVSVVVVL
                     LLAGLMGGSMLLWAVLAGAVVLALLCGVLGWMQLNVLRRMTLKSLPLRLAVSRLLRQP
                     WSTLSQLSAFSLSFMLLALLLVLRGDLLDRWQQQLPPESPNYFLINIATEQVAPLKAF
                     LAEHHIVPESFYPVVRARLTAINDKPTEGNEDEALNRELNLTWQNTRPDHNPIVAGNW
                     PPKADEVSMEEGLAKRLNVALGDTVTFMGDTQEFRAKVTSLRKVDWESLRPNFYFIFP
                     EGALDGQPQSWLTSFRWENGNGMLTQLNRQFPTISLLDIGAILKQVGQVLEQVSRALE
                     VMVVLVTACGMLLLLAQVQVGMRQRHQELVVWRTLGAGKKLLRTTLWCEFAMLGFVSG
                     LVAAIGAETALAVLQAKVFDFPWEPDWRLWIVLPCSGALLLSLFGGWLGARLVKGKAL
                     FRQFAG"
     gene            complement(78607..79701)
                     /gene="mnmH"
                     /locus_tag="RHX21_000073"
     CDS             complement(78607..79701)
                     /gene="mnmH"
                     /locus_tag="RHX21_000073"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HDV1985320.1"
                     /translation="MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMN
                     NDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQ
                     RSHIVQSWLYAAGIDYPLVEGGYKALRQTAIQATIELAQKPIVLIGGCTGSGKTLLVQ
                     QQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQDLRLWVLEDES
                     RMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHDFTHAYGDEQGWQ
                     EYCEYLHHGLSAIKRRLGLQRYNELAAQLDTALTTQLTTGSTDGHLAWLVPLLKEYYD
                     PMYRYQLEKKAEKVVFRGEWAEVAEWVKAQ"
     gene            complement(79770..80696)
                     /gene="allS"
                     /locus_tag="RHX21_000074"
     CDS             complement(79770..80696)
                     /gene="allS"
                     /locus_tag="RHX21_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator AllS"
                     /protein_id="HDV1985321.1"
                     /translation="MFDPETLRTFIAVAETGSFSKAAERLCKTTATISYRIKLLEENT
                     GVALFFRTTRSVTLTAAGEHLLSQARDWLSWLESMPSELQQVNDGVERQVNIVINNLL
                     YNPQAVAQLLAWLNERYPFTQFHISRQIYMGVWDSLLYEGFSLAIGVTGTEALANTFS
                     LDPLGSVQWRFVMAADHPLANVEEPLTEAQLRRFPAVNIEDSARTLTKRVAWRLPGQK
                     EIIVPDMETKIAAHLAGVGIGFLPKSLCQSMIDNQQLVSRVIPTMRPPSPLSLAWRKF
                     GSGKAVEDIVTLFTQRRPEISGFLEIFGNPRS"
     gene            80926..81408
                     /gene="allA"
                     /locus_tag="RHX21_000075"
     CDS             80926..81408
                     /gene="allA"
                     /locus_tag="RHX21_000075"
                     /EC_number="4.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate lyase"
                     /protein_id="HDV1985322.1"
                     /translation="MKLQVLPLSQEAFSAYGDVIETQQRDFFHINNGLVERYHDLALV
                     EILEQDRTLISINRAQPANLPLTIHELERHPLGTQAFIPMKGEVFVVVVALGDDKPDL
                     STLRAFITNGEQGVNYHRNVWHHPLFAWQRVTDFLTIDRGGSDNCDVESIPEQELCFA
                     "
     gene            81486..82301
                     /gene="allR"
                     /locus_tag="RHX21_000076"
     CDS             81486..82301
                     /gene="allR"
                     /locus_tag="RHX21_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor AllR"
                     /protein_id="HDV1985323.1"
                     /translation="MTEVRRRGRPGQAEPVAQKGAQALERGIAILQYLEKSGGSSSVS
                     DISLNLDLPLSTTFRLLKVLQAADFVYQDSQLGWWHIGLGVFNVGAAYIHNRDVLSVA
                     GPFMRRLMLLSGETVNVAIRNGNEAVLIGQLECKSMVRMCAPLGSRLPLHASGAGKAL
                     LYPLAEEELMSIILQTGLQQFTPTTLVDMPTLLKDLEQARELGYTVDKEEHVVGLNCI
                     ASAIYDDVGSVVAAISISGPSSRLTEDRFVSQGELVRDTARDISTALGLKAHP"
     gene            82391..84172
                     /gene="gcl"
                     /locus_tag="RHX21_000077"
     CDS             82391..84172
                     /gene="gcl"
                     /locus_tag="RHX21_000077"
                     /EC_number="4.1.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate carboligase"
                     /protein_id="HDV1985324.1"
                     /translation="MAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIR
                     HILARHVEGASHMAEGYTRATAGNIGVCLGTSGPAGTDMITALYSASADSIPILCITG
                     QAPRARLHKEDFQAVDIEAIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLV
                     DLPFDVQVAEIEFDPDMYEPLPVYKPAASRMQIEKAVEMLIQAERPVIVAGGGVINAD
                     AAALLQQFAELTSVPVIPTLMGWGCIPDDHELMAGMVGLQTAHRYGNATLLASDMVFG
                     IGNRFANRHTGSVEKYTEGRKIVHIDIEPTQIGRVLCPDLGIVSDAKAALTLLVEVAQ
                     EMQKAGRLPCRKEWVADCQQRKRTLLRKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTT
                     IGLSQIAAAQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPKRNVVAISGDFDFQ
                     FLIEELAVGAQFNIPYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFENINSSEVNGYG
                     VDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKALMAQYRVPVVVEVILERVTNISMGSE
                     LDNVMEFEDIADNAADAPTETCFMHYE"
     gene            84185..84961
                     /gene="hyi"
                     /locus_tag="RHX21_000078"
     CDS             84185..84961
                     /gene="hyi"
                     /locus_tag="RHX21_000078"
                     /EC_number="5.3.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxypyruvate isomerase"
                     /protein_id="HDV1985325.1"
                     /translation="MLRFSANLSMLFGEYDFLARFEKAAQCGFRGVEFMFPYDYDIEE
                     LKQVLASNKLEHTLHNLPAGDWAAGERGIACIPGREEEFRDGVAAAIRYARALGNKKI
                     NCLVGKTPAGFSSEQIHATLVENLRYAANMLMKEDILLLIEPINHFDIPGFHLTGTRQ
                     ALKLIDDVGCCNLKIQYDIYHMQRMEGELTNTMTQWADKIGHLQIADNPHRGEPGTGE
                     INYDYLFKVIENSDYNGWVGCEYKPQTTTEAGLRWMDPYR"
     gene            85061..85939
                     /gene="glxR"
                     /locus_tag="RHX21_000079"
     CDS             85061..85939
                     /gene="glxR"
                     /locus_tag="RHX21_000079"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HDV1985326.1"
                     /translation="MKLGFIGLGIMGTPMAINLARAGHQLHVTTIGPVADELLSLGAV
                     SVETARQVTEASDIIFIMVPDTPQVEEVLFGENGCTKASLKGKTIVDMSSISPIETKR
                     FARQVNELGGDYLDAPVSGGEIGAREGTLSIMVGGDEAVFERVKPLFELLGKNITLVG
                     GNGDGQTCKVANQIIVALNIEAVSEALLFASKAGADPVRVRQALMGGFASSRILEVHG
                     ERMIKRTFNPGFKIALHQKDLNLALQSAKALALNLPNTATCQELFNTCAANGGSQLDH
                     SALVQALELMANHKLA"
     gene            86108..87562
                     /locus_tag="RHX21_000080"
     CDS             86108..87562
                     /locus_tag="RHX21_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415044.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative allantoin permease"
                     /protein_id="HDV1985327.1"
                     /translation="MEHQRKLFQQRGYSEDLLPKTQSQRTWKTFNYFTLWMGSVHNVP
                     NYVMVGGFFILGLSTFSIMLAIILSAFFIAAVMVLNGAAGSKYGVPFAMILRASYGVR
                     GALFPGLLRGGIAAIMWFGLQCYAGSLACLILIGKIWPGFLTLGGDFTLLGLSLPGLI
                     TFLLFWLVNVGIGFGGGKVLNKFTAILNPCIYIVFGGMAIWAISLVGLGPIFDYIPSG
                     IQKAENSGFLFLVVINAVVAVWAAPAVSASDFTQNAHSFREQALGQTLGLVVAYILFA
                     VAGVCIIAGASIHYGADTWNVLDIVQRWDSLFASFFAVLVILMTTISTNATGNIIPAG
                     YQIAAIAPTKLTYKNGVLIASIISLLICPWKLMENQDSIYLFLDIIGGMLGPVIGVMM
                     AHYFVVMRGQINLDELYTAPGDYKYYDNGFNLTAFSVTLVAVILSLGGKFIPFMEPLS
                     RVSWFVGVIVAFAAYALLKKRTTAEKTGEQKTIG"
     gene            87622..88983
                     /gene="allB"
                     /locus_tag="RHX21_000081"
     CDS             87622..88983
                     /gene="allB"
                     /locus_tag="RHX21_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allantoinase AllB"
                     /protein_id="HDV1985328.1"
                     /translation="MSFDLIIKNGTVILENEARVVDIAVKGGKIAAIGQDLGDAKEVM
                     DASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDR
                     ASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDND
                     FRDVNDWQFFKGAQKLGELGQPVLVHCENALICDALGEEAKREGRVTAHDYVASRPVF
                     TEVEAIRRVLYLAKVAGCRLHVCHISSPEGVEEVTRARQEGQDVTCESCPHYFVLDTD
                     QFEEIGTLAKCSPPIRDLENQKGMWEKLFNGEIDCLVSDHSPCPPEMKAGNIMEAWGG
                     IAGLQNCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQ
                     PNSSYVLTNDDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILK
                     HQQ"
     gene            89040..90341
                     /locus_tag="RHX21_000082"
     CDS             89040..90341
                     /locus_tag="RHX21_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308602.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil/xanthine transporter"
                     /protein_id="HDV1985329.1"
                     /translation="MFNFAVSRESLLSGFQWFFFIFCNTVVVPPTLLSAFQLPQSSLL
                     TLTQYAFLATALACFAQAFCGHRRAIMEGPGGLWWGTILTITLGEASRGTPINDIATS
                     LAVGIALSGVLTMLIGFSGLGHRLARLFTPSVMVLFMLMLGAQLTTIFFKGMLGLPFG
                     IADPNFKIQLPPFALSVAVMCLVLGMIIFLPQRFARYGLLVGTITGWLLWYFCFPSSH
                     SLSGELHWQWFPLGSGGALSPGIILTAVITGLVNISNTYGAIRGTDVFYPQQGAGNTR
                     YRRSFVATGFMTLITVPLAVIPFSPFVSSIGLLTQTGDYTRRSFIYGSVICLLVALVP
                     ALTRLFCSIPLPVSSAVMLVSYLPLLFSALVFSQQITFTARNIYRLALPLFVGIFLMA
                     LPPVYLQDLPLTLRPLLSNGLLVGILLAVLMDNLIPWERIE"
     gene            90363..91508
                     /gene="glxK"
                     /locus_tag="RHX21_000083"
     CDS             90363..91508
                     /gene="glxK"
                     /locus_tag="RHX21_000083"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate 3-kinase"
                     /protein_id="HDV1985330.1"
                     /translation="MKIVIAPDSFKESLSAEKCCQAIKAGFSTLFPDANYICLPIADG
                     GEGTVDAMVAATGGNIVTLEVCGPMGETVNAFYGLTGDGKTAVIEMAAASGLMLVAPE
                     KRNPLLASSFGTGELIRHALDNGIRHIILGIGGSATVDGGMGMAQALGVRFLDADGQV
                     LAANGGNLARVASIEMDECDPRLANCHIEVACDVDNPLVGARGAAAVFGPQKGATPEM
                     VEELEQGLQNYARVLQQQTEINVCQMAGGGAAGGMGIAAAVFLNADIKPGIEIVLRAV
                     NLEQAVQGAALVITGEGRIDSQTAGGKAPLGVASVAKQFNVPVIGIAGVLGDGVEVVH
                     QYGIDAVFSILPRLAPLAEVLASGETNLFNSARNIACAIKIGQGIKN"
     gene            complement(91637..92422)
                     /gene="allE"
                     /locus_tag="RHX21_000084"
     CDS             complement(91637..92422)
                     /gene="allE"
                     /locus_tag="RHX21_000084"
                     /EC_number="3.5.3.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-ureidoglycine aminohydrolase"
                     /protein_id="HDV1985331.1"
                     /translation="MGYLNNVTGYRDDLLANRAIVKHGNFALLTPDGLVKNIIPGFEN
                     CDATILSTPKLGASFVDYLVTLHQNGGNQQGFGGEGIETFLYVISGNITAKAEGKTFA
                     LSEGGYLYCPPGSLMTFVNAQAEDSQIFLYKRRYVPVEGHAPWLVSGNASELERIHYE
                     GMDDVILLDFLPKELGFDMNMHILSFAPGASHGYIETHVQEHGAYILSGQGVYNLDNN
                     WIPVKKGDYIFMGAYSLQAGYGVGRGEAFSYIYSKDCNRDVEI"
     gene            complement(92433..93668)
                     /gene="allC"
                     /locus_tag="RHX21_000085"
     CDS             complement(92433..93668)
                     /gene="allC"
                     /locus_tag="RHX21_000085"
                     /EC_number="3.5.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allantoate deiminase"
                     /protein_id="HDV1985332.1"
                     /translation="MITHFRQAIEETLPWLSSFGADPTGGMTRLLYSPEWLETQQQFK
                     KRMAASGLETRFDEVGNLYGRLSGTEYPQEVVLSGSHIDTVVNGGNLDGQFGALAAWL
                     AIDWLKTQYGAPLRTVEVVAMAEEEGSRFPYVFWGSKNIFGLANPDDVRNICDAKGNS
                     FVDAMKACGFTLPNAPLTPRQDIKAFVELHIEQGCVLESNGQSIGVVNAIVGQRRYTV
                     TLNGESNHAGTTPMGYRRDTVYAFSRICHQSVEKAKRMGDPLVLTFGKVEPRPNTVNV
                     VPGKTTFTIDCRHTDAAVLRDFTQQLENDMRAICDEMDIGIDIDLWMDEEPVPMNKEL
                     VATLTELCEREKLNYRVMHSGAGHDAQIFAPRVPTCMIFIPSINGISHNPAERTNITD
                     LAEGVKTLALMLYQLAWQK"
     gene            complement(93690..94739)
                     /gene="allD"
                     /locus_tag="RHX21_000086"
     CDS             complement(93690..94739)
                     /gene="allD"
                     /locus_tag="RHX21_000086"
                     /EC_number="1.1.1.154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate dehydrogenase"
                     /protein_id="HDV1985333.1"
                     /translation="MKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSH
                     GAVRVEYYAERISKGGTNREPEFRLEETGPCSAILHADNAAGQVAAKMGMEHAIKTAQ
                     QNGVAVVGISRMGHSGAISYFVQQAARAGLIGISMCQSDPMVVPFGGAEIYYGTNPLA
                     FAAPGEGDEILTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGAPTTDPFAVHALL
                     PAAGPKGYGLMMMIDVLSGVLLGLPFGRQVSSMYDDLHAGRNLGQLHIVINPNFFFSS
                     KLFRQHLSQTMRELNAITPAPGFNQVYYPGQDQDIKQRKAAVEGIEIVDDIYQYLISD
                     ALYNTSYETKNPFAQ"
     gene            95056..96723
                     /locus_tag="RHX21_000087"
     CDS             95056..96723
                     /locus_tag="RHX21_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase FdrA"
                     /protein_id="HDV1985334.1"
                     /translation="MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKA
                     LLDTTGFWHDDFNNATPNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQSL
                     TQVRRWDSACQKLSDANLALISVAGEYAAELTNQALDRNLNVMMFSDNVTLEDEIQLK
                     TRAREKGLLVMGPDCGTSMIAGTPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGE
                     GITHAIGLGGRDLSREVGGISALTALEMLSADEKSEVLAFVSKPPAEAVRLKIVNAMK
                     ATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAITPASSGFIC
                     GLYTGGTLAAEAAGLLAGHLGVEADDTHHHGMMLDADGHQIIDLGDDFYTVGRPHPMI
                     DPALRNQLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARSDNQPLYA
                     IATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIRPLSPATQQHTPSLL
                     ENVAVINIGLRSFALELQSASKPVVHYQWSPVAGGNKKLARLLERLQ"
     gene            96733..97992
                     /locus_tag="RHX21_000088"
     CDS             96733..97992
                     /locus_tag="RHX21_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009029994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 domain-containing protein"
                     /protein_id="HDV1985335.1"
                     /translation="MFTSVAQANAAVIEQIRRARPHWLDVQPASSLISELNEGKTLLH
                     AGPPMRWQEMTGPMKGACVGACLFEGWAKDEAQALAILEQGEVNFIPCHHVNAVGPMG
                     GITSASMPMLVVENVTDGNRAYCNLNEGIGKVMRFGAYGEDVLTRHRWMRDVLMPVLS
                     AALGRMERGIDLTAMMAQGITMGDEFHQRNIASSALLMRALAPQIARLDHDKQHIAEV
                     MDFLSVTDQFFLNLAMAYCKAAMDAGAMIRAGSIVTAMTRNGNMFGIRVSGLGERWFT
                     APVNTPQGLFFTGFSQEQANPDMGDSAITETFGIGGAAMIAAPGVTRFVGAGGMEAAR
                     AVSEEMAEIYLERNMQLQIPGWDFQGACLGLDIRRVVETGITPLINTGIAHKEAGIGQ
                     IGAGTVRAPLACFEQALEALAESMGIG"
     gene            98003..98818
                     /locus_tag="RHX21_000089"
     CDS             98003..98818
                     /locus_tag="RHX21_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 domain-containing protein"
                     /protein_id="HDV1985336.1"
                     /translation="MTIIHPLLASRSAPNYRQSWRLAGVWRRAINLMTESGELLTLHR
                     QGSGFGPGGWVLRRAQFDALCGGLCGNERPQVVAQGIRLGRFTVKQPQRYCLLRITPP
                     SHPQPLAAAWMQRAEETGLFGPLAMAASDPLPAELRQFRHCFQAALNGVKTDWRHWLG
                     KGPGLTPSHDDTLSGMLLAAWYYGALDARAGRPFFACSDNLQLVTTAVSVSYLRYAAQ
                     GYFASPLLHFVHALSCPKRTAVAIDSLLALGHTSGADTLLGFWLGQQLLQGKP"
     gene            98815..99708
                     /locus_tag="RHX21_000090"
     CDS             98815..99708
                     /locus_tag="RHX21_000090"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HDV1985337.1"
                     /translation="MKTLVVALGGNALLQRGEALTAENQYRNIASAVPALARLARSYR
                     LAIVHGNGPQVGLLALQNLAWKKVEPYPLDVLVAESQGMIGYMLAQSLSAQPQMPPVT
                     TVLTRIEVSPDDPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRDGKYLRRVVASPQP
                     RKILDSEAIELLLKEGHVVICSGGGGVPVTEDGAGSEAVIDKDLAAALLAEQINADGL
                     VILTDADAVYENWGTPQQRAIRHATPDELAPFAKADGSMGPKVTAVSGYVRSRGKPAW
                     IGALSRIEDTLAGEAGTCISL"
     gene            complement(99845..100912)
                     /gene="purK"
                     /locus_tag="RHX21_000091"
     CDS             complement(99845..100912)
                     /gene="purK"
                     /locus_tag="RHX21_000091"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706400.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HDV1985338.1"
                     /translation="MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPAAVPFQQS
                     VITAEIERWPETALTRELARHPAFVNRDVFPIIADRLTQKQLFDKLHLPTAPWQLLAD
                     RSEWPAVFDRLGELAIVKRRTGGYDGRGQWRLRANETEQLPAECYGECIVEQGINFSG
                     EVSLVGARGFDGSTVFYPLTHNLHQDGILRTSVAFPQANAQQQAQAEEMLSAIMQELG
                     YVGVMAMECFVTPQGLLINELAPRVHNSGHWTQNGASISQFELHLRAITDLPLPQPVV
                     NNPSVMINLIGSDVNYDWLKLPLVHLHWYDKEVRPGRKVGHLNLTDSDTSRLTATLEA
                     LIPLLPPEYASGVIWAQSKFS"
     gene            complement(100909..101418)
                     /gene="purE"
                     /locus_tag="RHX21_000092"
     CDS             complement(100909..101418)
                     /gene="purE"
                     /locus_tag="RHX21_000092"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HDV1985339.1"
                     /translation="MSSRNNPARVAIVMGSKSDWATMQFAAEIFEILNVPHHVEVVSA
                     HRTPDKLFSFAESAEENGYQVIIAGAGGAAHLPGMIAAKTLVPVLGVPVQSAALSGVD
                     SLYSIVQMPRGIPVGTLAIGKAGAANAALLAAQILATHDKELHQRLNDWRKAQTDEVL
                     ENPDPRGAA"
     gene            complement(101536..102258)
                     /gene="lpxH"
                     /locus_tag="RHX21_000093"
     CDS             complement(101536..102258)
                     /gene="lpxH"
                     /locus_tag="RHX21_000093"
                     /EC_number="3.6.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-2,3-diacylglucosamine diphosphatase"
                     /protein_id="HDV1985340.1"
                     /translation="MATLFIADLHLCVEEPAITAGFLRFLAGEARKADALYILGDLFE
                     AWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKV
                     LELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQMLFLALPLFVRKRIAARMRANS
                     KEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGA
                     WHTEGSMVKVTADDVELIHFPF"
     gene            complement(102261..102755)
                     /gene="ppiB"
                     /locus_tag="RHX21_000094"
     CDS             complement(102261..102755)
                     /gene="ppiB"
                     /locus_tag="RHX21_000094"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase B"
                     /protein_id="HDV1985341.1"
                     /translation="MVTFHTNHGDIVIKTFDDKAPETVKNFLDYCREGFYNNTIFHRV
                     INGFMIQGGGFEPGMKQKATKEPIKNEANNGLKNTRGTLAMARTQAPHSATAQFFINV
                     VDNDFLNFSGESLQGWGYCVFAEVVEGMDVVDKIKGVATGRSGMHQDVPKEDVIIESV
                     TVSE"
     gene            102929..104314
                     /gene="cysS"
                     /locus_tag="RHX21_000095"
     CDS             102929..104314
                     /gene="cysS"
                     /locus_tag="RHX21_000095"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HDV1985342.1"
                     /translation="MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTF
                     VAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHKDFDA
                     LNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDL
                     DQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLG
                     NHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFT
                     VRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAG
                     GEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLG
                     LLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLE
                     DGPQGTTWRRK"
     gene            complement(104350..104871)
                     /locus_tag="RHX21_000096"
     CDS             complement(104350..104871)
                     /locus_tag="RHX21_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDV1985343.1"
                     /translation="MPTVITHAAVPLCIGLGLGSKVIPPRLLFAGIILAMLPDADVLS
                     FKFGVAYGNVFGHRGFTHSLVFAFVVPLLCVLIGRRWFRAGLIRCWLFLTVSLLSHSL
                     LDSVTTGGKGVGWLWPWSDERFFAPWQVIKVAPFALSRYTTPYGHQVIISELMWVWLP
                     GMVLMGMLWWRRR"
     gene            complement(104979..105191)
                     /gene="ybcJ"
                     /locus_tag="RHX21_000097"
     CDS             complement(104979..105191)
                     /gene="ybcJ"
                     /locus_tag="RHX21_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308617.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated protein YbcJ"
                     /protein_id="HDV1985344.1"
                     /translation="MATFSLGKHPHVELCDLLKLEGWSESGAQAKIAIAEGQVKVDGA
                     VETRKRCKIVAGQTVSFAGHSVQVVA"
     gene            complement(105193..106059)
                     /gene="folD"
                     /locus_tag="RHX21_000098"
     CDS             complement(105193..106059)
                     /gene="folD"
                     /locus_tag="RHX21_000098"
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase
                     FolD"
                     /protein_id="HDV1985345.1"
                     /translation="MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSN
                     PASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDALNADNTIDGILVQLPLP
                     AGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGL
                     NAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPG
                     DWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTL
                     QACVEYHDPQDE"
BASE COUNT        25853 a        26826 c        28384 g        25252 t
ORIGIN      
        1 ttcaggctaa atgtgtgctt attacttgga cctttatggc actgtattta ttcattaaat
       61 ggatatttgg tggttaatta ttatggaaat atatgacagt gaggacataa aggtatacat
      121 gttaactaaa agaatattat tttctgtaat gctgatagtt tcaccaagcg tggtggccag
      181 cgagaaagcg catgaattgt atgacagcat atacggtggt aaacctgctc ccgatgttat
      241 aaatacactg cataaaatgg ctgaatcggg agatatcgac gcgcagagcc tgttaggctg
      301 ggaatattat cagcctcgtt atgataccaa acctgatgtt caggaagcga ttaaatggtt
      361 cgagttagcg gctaaacaag gtgacagaga agctccgtta gcgctggggg gtatctacta
      421 cgacggtgag caggtgcggg tggattatgc caaagcgtat gcactattta atcaggccgc
      481 gcagcacggt gtgaatttag catggtccag gttgggcatt atgtacgcca atggtcagta
      541 tgttgaggta gattgtaaga aagcgaagga atatcttgat aaaggtgtcc acatttatgg
      601 tggcccagaa gactttctgg ctacttgtcg aaaagacatg attgacagaa aaacggttga
      661 cgatacgtta cccgtgatta cggttacccg ttctgggatg cgagataatt ttttagataa
      721 aggtttttcc tgcatggata gcctcttcgc caccaccaat aaattaggcg aagtggccaa
      781 tcttcgcgtg acattcagca ttcgtcgccc atccggtaag gagattaacc aaacggttgg
      841 cttcgcgcct ttcggtttaa accggctgaa tattagcttt actgattacc tatttggttc
      901 atttaccagt aattcgtctc ttattcttta taaaccggaa tttgagcgaa aatcttgtgc
      961 aactgtaagg accacaatcg ttgccgcaac ggcaaccatt aacggcaagg atgtggagtt
     1021 gctgaaagcg ggggcaattg aacaaaagtg gtaacgctgc tcagcccccg gctgaggcaa
     1081 aacttgccct ggcgggtggc gataataatc taagccgcga gaatatgctg aatcgccaaa
     1141 aacataggta cagcaccaaa agcatttggt gtcgctgaaa gctgaacaaa gccgagacga
     1201 gcataaaaat taatggcggc agggtcagca tcaagataaa cccctttaat tggtaatgcc
     1261 tggtgaatta tttttacatg ttcaaaaaaa tcacatagta ggtcctgacc aaagccccgc
     1321 ttttgatact tccgtgctac ccccaacatg actaatctga caacaccaat ttctgaaggt
     1381 tgtgaaccct gaaggacgcc agaaacgcgt tgtttttcca gcgaatatgc cgtaaaagta
     1441 cagatgccga tcagttcacc actttgtctg tcaataagtg ctttagccgc acagtcgcta
     1501 ttacgcacac ttttctttag cgatgcgcgt acaaatttat cgataacagg gttaccgcaa
     1561 tcaaactgtt tttgcccagg ataagtaata tcagactgat aattacagga gaggactatg
     1621 ggcagagtaa tctcttcatg cttgtcgacc atcgctgttt ttccttttca ttaacgcctt
     1681 gagggcgagc gtcggttgag caggttcagc gatgagttgg ttcatcagtt cccagctttg
     1741 attcgaaagc tcacggcgac gttggttatc aagcacactt tcggcgcgtt ccatagcagc
     1801 gctcaaaata aaagcgctta aatctacccc aacggcttgc gcagcttcac gaagtttgtt
     1861 tttggcgtcg ggactggttt tgagttcgac ccgcgcattt ttcagcgttt tatcgacatc
     1921 gggtagagtg gctgtttttc caggcattat gacctctttg attaactgaa tgaaatcgta
     1981 gggagtcgat ctcatacata atacggctat caaccgtatg attaatttat gttcatctgc
     2041 tcactctgtc aagacatacg gttattagcc gtatctctga tctcagacaa taaaaaaggt
     2101 gccgtagcac ctttttaata gagaggtttt gttaccacac agcagccagc agcgtatgcg
     2161 agtccggtac cataaaatca acggacatca tcaccgagag ggcagtgatg gcgatgatag
     2221 agaagccgaa cagcttgcgc gcccagattc tgtcatcagc aactttataa ccgcgcagag
     2281 ccatacctaa ccaccagacg ctaaccgccg cggcgaccac cagatattta tatccagcgt
     2341 aaccgccaag agagagcatc agcgtggcaa cggcaaaggc gatgatatac agcgtgatgt
     2401 gattcttcgc caccgaaatg ccttttacca ctggcaatac cggaatgttt gccgcctggt
     2461 aatccttaaa gcggaaaatg gcgatggcat aggagtgagg catctgccac aggctgaaga
     2521 tagccagcag gatcgctgcg ccgctatcga actcgccggt tactgcacag tagccaatca
     2581 ccggcggcgc agcgccggag agcgaaccaa tcaatgtgcc gtagactgag tggcgtttca
     2641 tgtacaggct atagacgccg acataaacca caaagcccat cacccccagc cagcaggcca
     2701 gcggattcgc gccaaaccac agcagcataa agccagcaat acccagcaag gtggcgtaca
     2761 ccagcgagac agcaggagag atcaggcctt taaccagcac ccgattcttc gtcctttcca
     2821 tctttctgtc gatatccctg tcgatgtagt tgttaaacac acaacccgac gccacaacca
     2881 gtgacacccc aaccagcgtg tagataaaca ggggataatc aatgctgccc tttgaggcca
     2941 gcaggaatcc cccaatcacc gagatcaggt tgccaaagat gatgcctggt ttcgttactt
     3001 gcaggtattg cttaaacatc ataaccgccg ctcttagtgc atcatcatgt tgtagttgag
     3061 gttccacata atccagatgg agcctacaac caggatagcg atgattagca cggtgaagac
     3121 aaacgccgtc atgttccagc cttcatctga tttggtattc atgtgcagga agcacaccag
     3181 atgcaccaga acctgtacca ctgccattgc caggattgtt cccagaatta cggccggaga
     3241 ggcagcccct gtcatcacca tccagaacgg aatcaccgtc agaatgatcg acaggataaa
     3301 gcctgtcatg taggttttta cgctgccatg ggacgcgccg ctgtgatcgg tagaatgact
     3361 cattacatcg cccccatcag ataaacaaca gtgaacacac agatccaaac cacatccagg
     3421 aagtgccaga acaggctcag gcacatgatg cgggtacggt tagtgctggt caggccgcga
     3481 cgagcgattt gtaccatcag caccgccatc cagataagac cggaagtgac gtgcagaccg
     3541 tgcgtgccga ccagcgcaaa gaacgctgac aggaagccgc tgcgatccgg acccatgccg
     3601 ttaacaatca ggtgatggaa ttcgtagatt tccatcccga taaatccggc accaaacaac
     3661 caggtcaacg ccagccagga gataacctgg cttttgttgt ttttgtacat ggcgatagcc
     3721 gccatgccgt aggtgatgga gctgaacaac agcaagaaag tttcaaccag aacgaacggc
     3781 agttcgaaaa tgtccttacc tgtcggaccg cctgcggtgc cgttcaccag aacggcatag
     3841 gtagcaaaca agattgagaa cagaatgcag tcgctcatca ggtagatcca aaatccgaag
     3901 attttggttc cgcctgcatc gtggtgcccg tgttcgtgcg cgtgggcagt cgcgtgcgtc
     3961 aaagtatcag ttgccatttt tcagccctgc cttagtaatc tcatcgaaat gctggttttc
     4021 cagtttttcg atttctgcca ccggcacgta gtaatccacg tcctcgtcga agcttttcac
     4081 gatccaggtg atgatcatgc ctgcgaagcc aacaatcgcc agccaccaga tatgccagat
     4141 catggcgaaa ccgaagatgg tggagaaagc tgcaatgacg atacctgcac cgctgttttt
     4201 cggcatatga atttcttcat agtggtcagg ctttttatac gcttcgcctt tctctttcat
     4261 ttcccagaat gcatcacgct cgtgaacgtg cggcacaacg gcaaagttat agaacggagg
     4321 cggggaagag gttgcccact ccagcgtacg gccaccccac gggtcgccag tcaggtcacg
     4381 gttctggtcg cggtcgcgaa tagaaacgta catctgaata acgaggcaga gaatacccag
     4441 cgcaatcagt actgcaccgc tagctgcaat catcagcatg gtgtggaact gcgggtcaat
     4501 ctgctggctc aaacgacggg tcatgcccat gaagcccagc gcatacagcg gcataaaggc
     4561 aacgaagaag ccgatgatcc agaaccagaa cgcgcgttta ccccaggttt cattcagttt
     4621 gaaaccgaag gctttaggcc accagtaggt catccctgcg aagcagccga agaccacgcc
     4681 gccgatgatc acgttatgga agtgcgcaat caggaacagg ctgttatgca gaacgaagtc
     4741 cgcgcccggt actgccagca gcacgccagt catcccgccc accgagaaag tgacgataaa
     4801 accgatggtc cacagcatcg cagaatggaa cacgatgcgg ccctgataca tggtgaacag
     4861 ccagttgaag atcttcaccc cggtcgggat ggcgataatc attgtggtga taccaaagaa
     4921 ggcgtttacg ttcgcgcccg cacccatcgt aaagaagtgg tgcagccaaa cgatgaacga
     4981 cagcacggtg atacagacgg ttgcccatac cagcgaggta taaccaaaca gacgtttacg
     5041 cgagaaggtt gccgcaattt cggagaacac accgaaaaca ggcaggatca ggatgtaaac
     5101 ttccgggtgg ccccaggccc aaatcaggtt gatgtacatc atcatgttgc cacccatatc
     5161 gttggtaaag aaatgggtgc ccagatagcg atccagggtc aacaacgcga cggtaaccgt
     5221 cagaattggg aaggaagcaa taatcagtac gttcgcgcac agtgatgccc aggtaaatac
     5281 tggcatcttg aacatggtca tgcccggtgc gcgcatcttc agaatggtaa cgaagaagtt
     5341 gataccggta agcgtcgtac ctataccgga tagctggaga ctccatatcc agtaatcaac
     5401 accgactccc ggactgtact ctattcccga tagcggtgga taggccagcc agccggtctg
     5461 cgcaaattcg cccacgccga gagaaacgtt aaccagaatc acaccaacaa cagtaaacca
     5521 gaagcttaag ttgttgagga acgggaacgc aacgtcacgc gcgccgatct gcagcggaac
     5581 caccaggttc atcagaccga taacgaaagg catcgccacg aagaagatca taatcacgcc
     5641 gtgcgcggtg aagatctgat cgtagtggtg aggtggcagg aagcccgctt cacccgccga
     5701 ggcaagagcc tgctggctac gcatcataat ggcgtcagca aaaccacgca gcaacatcac
     5761 aatcgccacg atgatataca tgataccgag gcgtttatgg tcgacggagg tcagccactc
     5821 tttccacagg taggtccact taccgaagta agtgatcagg ccaacgagcg ccagacctcc
     5881 caaaataatg ccagcgatcg taaccatgac gataggttca tggaacggga ctgcatcaag
     5941 tgataatttt ccgaacatct ttattcttcc tcaacccctt taatgggcgg attccgcgtg
     6001 gctcatgtcc atgccttcca taccttcgtg tgcactgtgc tcaccttctg gctgggtcat
     6061 gtccatgctc ttaccgtgag ccataaactt gttaatcaca tcggcaaaca agtctggttt
     6121 cacgttggag aaatattcca cctggttgta ttcgctaggc gcggccagtt tttcgaacgc
     6181 agccatgtca gacatggtgt tcggcgactg tttcgctttt gcgacccatt ggtcgaattc
     6241 ggcgcgatcc ggtgttgcaa tagctttgaa cttcatgcct gagaagcccg gcccgctgta
     6301 gctggcggag ataccgtcat aagtaccggg ttcgttggcg atcagatgca ggcgagtctg
     6361 cataccggcc atggcataaa tctggctacc cagacgcgga atgaagaagg agttcatcac
     6421 ggagttggag gtcactttga agtacaccgg agtgttcgcc gggaaagcga tttcattcac
     6481 ggtagcaatg ccctgttccg ggtagatgaa gaaccatttc cagtccatgg aaaccacttc
     6541 gatggtaatg ggcttctcgt cgtgtgccag cggcttgcta ggctcaagag cgtgagtggt
     6601 tttccaggtc agtaccgcaa ggaagatgat gattaagata ggcaccgtcc agaccacagc
     6661 ttccacttta ttggagtgtg accagttcgg gctgtactta gcatctttat tgctcgcacg
     6721 gtacttccag gcgaaaccaa cagccatcaa gattgcggga ataacgacaa tcaacatcag
     6781 gccaaatgcc gtcagtatca gtgaacgttg ctccagacca atctgtcctt tgggatctaa
     6841 cagcgcagaa ttacagccac tgagcaatac agtgcctgca aataatgaca accatcccaa
     6901 acttttattg tatttcctga gtctcattta acgacctcaa ttccacggga tctggtggcg
     6961 tttaaagtgt gtgggcattt tacgggaagg ttacattact gtaaacatga ttaaattcct
     7021 gttacttgga tttggctgtc aggtcacata tgttgcaaaa catatcaagt tgattttaag
     7081 aagctgttgc aaaagggcgt tataacgaaa ggggagtgca gaaggagttt ggacgggcaa
     7141 ttggtataac caatacaaaa taaaacaatt atttaacaaa taattatcat taaggtgaca
     7201 actgggtagt gagaaaataa aaactaatta gctgaatcgt gtaaggaaaa tagaattcat
     7261 aaatagcgtc aataatttcc aaacgctaag ccgcacaaaa gaacaaatat tattaagcga
     7321 tactgatgtt tatttagccg taataattac ggcgagtgat tactacagct aaataatatt
     7381 tacagattac gtcagatgcg tttttcgtag agccagataa tccagcaaac caccaagcac
     7441 gacgccagaa agggcgacta aaaccccgac ttccagcaga gcaggcagga aagagaagtg
     7501 cgtcaaatcc agcgtgtcca tcgtcaacag cagtaaccac acggccaaca ggctgacgcc
     7561 cgccgccagt gtccacatgg caaaggcata acctgccgga tattcggtac gggagataaa
     7621 gttgtcattt actcgtgtat attcaagcgt ctggcggcaa accagcagca aaataagccc
     7681 cggtacggca gcggcgacgg agaatagata gaatgtcgac cagccgtgtg cttcaacaaa
     7741 ccaacccgcc acggggccga cataaactcg tcctacagcg gaaagcgctg agagcagggc
     7801 aaattgagta gcggaaaatg acttattaca cagcgtcatt aacagcgcga caaaggctga
     7861 tgtgcccatc ccgccacaga ggttttcgaa aaagacggct gcgcccatgc tgtagagatg
     7921 cttatcagta atcgacagca gccagtaacc agcgttagac gcaccttgta aaatgccgaa
     7981 aatcagcagc gcccggaaca gcgacaggcg ctgcatcaaa atcccaccgt acaatgcgcc
     8041 aacaatggtc gccagtaagc caagcgtttt gttaaccacg cctacttcac ccgcatcaaa
     8101 cccgacgccg cgaatcaaaa acgtggttgt caggctcatg gcgaatgcgt cgcccagctt
     8161 atacagcacg ataagaagca aaataagcca ggcattattg cgaccaaaga aatctcgcag
     8221 aggtgcaaca accgcttgtt ccagcgtttt tggcacagga atggtgtcgg tcggttctgg
     8281 tgcaagcaac gtcgcgataa tacaggggat caacagcgcc gccatcaacc agtacatgcc
     8341 ctgccagccc agccatttat ctgccagcca cagggctaag ccgccggaaa ccagcatccc
     8401 taaacggtaa cccagaacgc tgattgccgc gcccgcacca cgttcttctg ccgggagcac
     8461 atcggttttc cacgcatcga agacaatatc ctgggaggcc gagcaaaaag cgatcaccac
     8521 cgccagtgcc gccatccagc ggagttgggt gccaggttcg agaaaaccca tcgccgcaat
     8581 ggcgactaat aacaggattt gcgtggcgag cagccaaccg cgccgccgcc caaaaaatgg
     8641 gggcgtgtag cggtccatca gcggtgacca gaggaattta aaaacgtaag cctggcctac
     8701 cagagagaag aaaccaatgg ttttgagatc aatattctcg accgtcatcc aggcctgtaa
     8761 ggtgccggat gtcagggcga gcggtagccc ggaagcaaaa cccaggatca gcaatatggc
     8821 tgaacgcggc tgttgaaaaa tacgtaaata ttgactggac atgggcgtct acaggcccgg
     8881 tttgcaccgg gccagagggc agaaattaac gcgcgttctg cttgataaat tcgtgaatgc
     8941 tggtgtcctg agacatatca gcgatggtat cggtcagcac actgttaacc gcatcggcga
     9001 tatttttgtt ggaggcctgg aacgcacctt caacgttgta gctggcacga tagtttttgg
     9061 tcattttgtt gccattctgc gcggtagcga tgatggcgat atccgctttg gtagcgatgt
     9121 tatagcgcac gttgccctgg gacacgtcag catacagttg gctaacgatg atttgcagat
     9181 taaccgggcc attcggacca accatgtaac cacgcgcggt catctgtttt tccagcactt
     9241 cttgcagcag gaaacgcaga tctcgggagg cggtcagggt aacgatttga ttatcgcggg
     9301 tgacttttgc cagcgcctga tcggtacgct gatcggcacc attaatgctt acggtgacgc
     9361 ccatcaggct tggatcctgc tgtggcagtg taatcgtcgg ggaaacttca atagttgttg
     9421 gcggttttgc gcatcctgca agcataaaca gagcaactaa cgggaagagg atttttttga
     9481 acatgtttgg gctctcagag actcttaagc gtgtttggta aaaattcccg ccatcataac
     9541 attgccaacg gcgaggggaa gtgggtaagg catgtaaatt catcatgttg acgaaataat
     9601 cacccctggt aaaagaaacg ctgatgcgag gcctgtgttt caatctttaa atcagtaaac
     9661 ttcatacgct tgacggaaaa accaggacga aacctaaata tttgttgtta agctgcaatg
     9721 gaaacggtaa aagcggctag tatttaaagg gatggatgac atctcagcgt tgtcggagga
     9781 gatatttcat gatgatacgt gagcggatag aagaaaaatt aagggcggcg ttccaacccg
     9841 tattcctcga agtagtggat gaaagctatc gtcacaatgt cccagccggc tctgaaagcc
     9901 attttaaagt tgtgctggtc agcgatcgtt ttacgggtga acgttttctg aatcgtcatc
     9961 gaatgattta cagtacttta gcggaggaac tctctactac cgttcatgcg ctggctctgc
    10021 atacttacac tattaaggag tgggaagggt tgcaggacac cgtctttgcc tctcctccct
    10081 gtcgtggagc aggaagcatc gcgtaaaaac gcatttgcaa ctgtcggcgc ttttccagta
    10141 tgttgctaaa gattttatga aaaacggcct gcgggccgtt ttgttttgtc tggattttgc
    10201 gctttttgcc cagcattcag acgaaaattg cccgggaatt gtgaaaaaat acgcgacagc
    10261 gcgcaataac cgttctcgac tcataaaagt gatgccgcta taatgccgcg tcctatttga
    10321 atgctttcgg gatgattctg gtaacaggga atgtgattga ttataagaac atcccggttc
    10381 cgcgaagcca acaacctgtg cttgcggggt aagagttgac cgagcactgt gattttttga
    10441 ggtaacaaga tgcaagtttc agttgaaacc actcaaggcc ttggccgccg tgtaacgatt
    10501 actatcgctg ctgacagcat cgagaccgct gttaaaagcg agctggtcaa cgttgcgaaa
    10561 aaagtacgta ttgacggctt ccgcaaaggc aaagtgccaa tgaatatcgt tgctcagcgt
    10621 tatggcgcgt ctgtacgcca ggacgttctg ggtgacctga tgagccgtaa cttcattgac
    10681 gccatcatta aagaaaaaat caatccggct ggcgcaccga cttatgttcc gggcgaatac
    10741 aagctgggtg aagacttcac ctactctgta gagtttgaag tttatccgga agttgaactg
    10801 cagggtctgg aagcgatcga agttgaaaaa ccgatcgttg aagtgaccga tgctgacgtt
    10861 gacggcatgc tggatactct gcgtaaacag caggcaacct ggaaagaaaa agacggcgct
    10921 gttgaagcag aagaccgcgt aaccatcgac ttcaccggtt ctgtagacgg cgaagagttc
    10981 gaaggcggta aagcgtctga tttcgtactg gcgatgggcc agggtcgtat gatcccgggc
    11041 tttgaagacg gtatcaaagg ccacaaagct ggcgaagagt tcaccatcga cgtgaccttc
    11101 ccggaagaat accacgcaga aaacctgaaa ggtaaagcag cgaaattcgc tatcaacctg
    11161 aagaaagttg aagagcgtga actgccggaa ctgactgcag aattcatcaa acgtttcggc
    11221 gttgaagatg gttccgtaga aggtctgcgc gctgaagtgc gtaaaaacat ggagcgcgag
    11281 ctgaagagcg ccatccgtaa ccgcgttaag tctcaggcga tcgaaggtct ggtaaaagct
    11341 aacgacatcg acgtaccggc tgcgctgatc gacagcgaaa tcgacgttct gcgtcgccag
    11401 gctgcacagc gtttcggtgg caacgaaaaa caagctctgg aactgccgcg cgaactgttc
    11461 gaagaacagg ctaaacgtcg cgtagttgtt ggcctgctgc tgggcgaagt tatccgcacc
    11521 aacgagctga aagctgacga agagcgcgtg aaaggcctga tcgaagagat ggcttctgcg
    11581 tacgaagatc cgaaagaagt tatcgagttc tacagcaaaa acaaagaact gatggacaac
    11641 atgcgcaatg ttgctctgga agaacaggct gttgaagctg tactggcgaa agcgaaagtg
    11701 actgaaaaag aaaccacttt caacgagctg atgaaccagc aggcgtaatt tacgcagcat
    11761 aacgcgctaa attcgcacaa aggcccgtca ccgccaggtg gtgggctttt ttttgtcatg
    11821 aattttgcat ggaaccgtgc gaaaagcctc tttcggtgtt agcgtaacaa caaaagattg
    11881 ttatgcttga aatatggtga tgccgtaccc ataacacagg gactagctga taatccgtcc
    11941 ataaggttac aatcggtaca gcaggttttt tcaattttat ccaggagacg gaaatgtcat
    12001 acagcggcga acgagataac tttgcacccc atatggcgct ggtgccgatg gtcattgaac
    12061 agacctcacg tggtgagcgc tcttttgata tctattctcg tctacttaag gaacgcgtca
    12121 tttttctgac tggccaggtt gaagaccaca tggctaacct gattgtggcg cagatgctgt
    12181 tcctggaagc agaaaaccca gaaaaagata tctatctgta cattaactcc ccaggcgggg
    12241 tgatcactgc cgggatgtct atctatgaca ccatgcagtt tatcaagcct gatgtcagca
    12301 ccatctgtat gggccaggcg gcctcgatgg gcgctttctt gctgaccgca ggggcaaaag
    12361 gtaaacgttt ttgcctgccg aattcgcgcg tgatgattca ccaaccgttg ggcggctacc
    12421 agggccaggc gaccgatatc gaaattcatg cccgtgaaat tctgaaagtt aaagggcgca
    12481 tgaatgaact tatggcgctt catacgggtc aatcattaga acagattgaa cgtgataccg
    12541 agcgcgatcg cttcctttcc gcccctgaag cggtggaata cggtctggtc gattcgattc
    12601 tgacccatcg taattgatgc cagaggcgca actgtgccgc tatacttatc cagggcggca
    12661 caacgctgta agcggcttgc gcctgagaat ggcatttgcg tcgtcgtgtg cggcacaaag
    12721 aacaaagaag aggttttgac ccatgacaga taaacgcaaa gatggctcag gcaaattgct
    12781 gtattgctct ttttgcggca aaagccagca tgaagtgcgc aagctgattg ccggtccatc
    12841 cgtgtatatc tgcgacgaat gtgttgattt atgtaacgac atcattcgcg aagagattaa
    12901 agaagttgca ccgcatcgtg aacgcagtgc gctaccgacg ccgcatgaaa ttcgcaacca
    12961 cctggacgat tacgttatcg gccaggaaca ggcgaaaaaa gtgctggcgg tcgcggtata
    13021 caaccattac aaacgtctgc gcaacggcga taccagcaat ggtgtcgagt tgggcaaaag
    13081 taacattctg ctgatcggtc cgaccggttc cggtaaaacg ctgctggctg aaacgctggc
    13141 gcgcctgctg gacgtcccgt tcaccatggc cgacgcaacc acgctgaccg aagccggtta
    13201 tgtgggcgaa gacgttgaaa acatcattca gaaactgttg cagaaatgcg actacgatgt
    13261 ccagaaagca cagcgtggta ttgtctacat cgatgaaatc gacaagattt ctcgtaagtc
    13321 ggacaacccg tctattaccc gtgacgtttc cggtgaaggc gtacagcagg cactgttgaa
    13381 actgatcgaa ggtactgttg ctgccgttcc accgcagggc gggcgtaagc atccgcagca
    13441 ggaatttttg caggttgata cctccaagat cctgtttatt tgtggcggtg cgtttgccgg
    13501 tctggataaa gtgatttccc accgtgtaga aaccggctcc ggcattggtt ttggcgcgac
    13561 ggtaaaagcg aagtccgaca aagcaagcga aggcgagctg ctggcgcagg ttgaaccgga
    13621 agatctgatc aagtttggtc ttatccctga gttcattggt cgtctgccgg ttgtcgcaac
    13681 gttgaatgaa ctgagcgaag aagctctgat tcagatcctc aaagagccga aaaacgccct
    13741 gaccaagcag tatcaggcgc tgtttaatct ggaaggcgtg gatctggaat tccgtgacga
    13801 ggcgctggat gctatcgcta agaaagcgat ggcgcgtaaa accggtgccc gtggcctgcg
    13861 ttccatcgta gaagccgcac tgctcgatac catgtacgat ctgccgtcca tggaagacgt
    13921 cgaaaaagtg gttatcgacg agtcggtaat tgatggtcaa agcaaaccgt tgctgattta
    13981 tggtaagccg gaagcgcaac aggcatctgg tgaataatta accattccca tacaattagt
    14041 taaccaaaaa ggggggattt tatctcccct ttaatttttc ctctattctc ggcgttgaat
    14101 gtgggggaaa catccccata tactgacgta catgttaata gatggcgtga agcacagtcg
    14161 tgtcatctga ttacctggcg gaaattaaac taagagagag ctctatgaat cctgagcgtt
    14221 ctgaacgcat tgaaatcccc gtattgccgc tgcgcgatgt ggtggtttat ccgcacatgg
    14281 tcatcccctt atttgtcggg cgggaaaaat ctatccgttg tctggaagcg gcgatggacc
    14341 atgataaaaa aattatgctg gtcgcgcaga aagaagcttc aacggatgag ccgggtgtaa
    14401 acgatctttt caccgtcggg accgtggcct ctatattgca gatgctgaaa ctgcctgacg
    14461 gcaccgtcaa agtgctggtc gaggggttac agcgcgcgcg tatttctgcg ctctctgaca
    14521 atggcgaaca cttttctgcg aaggcggagt atctggagtc gccgaccatt gatgagcggg
    14581 aacaggaagt gctggtgcgt actgcaatca gccagttcga aggctacatc aagctgaaca
    14641 aaaaaatccc accagaagtg ctgacgtcgc tgaatagcat cgacgatccg gcgcgtctgg
    14701 cggataccat tgctgcacat atgccgctga aactggctga caaacagtcc gttctggaga
    14761 tgtccgacgt taacgaacgt ctggaatatc tgatggcaat gatggaatcg gaaatcgatc
    14821 tgctgcaggt tgagaaacgc attcgcaacc gcgttaaaaa gcagatggag aaatcccagc
    14881 gtgagtacta tctgaacgag caaatgaaag ctattcagaa agaactcggt gaaatggacg
    14941 acgcgccgga cgaaaacgaa gccctgaagc gcaaaatcga cgcggcgaag atgccgaaag
    15001 aggcaaaaga gaaagcggaa gcagagttgc agaagctgaa aatgatgtct ccgatgtcgg
    15061 cagaagcgac cgtagtgcgt ggttatatcg actggatggt acaggtaccg tggaatgcgc
    15121 gcagcaaggt caaaaaagac ctgcgtcagg cgcaggaaat ccttgatacc gaccattatg
    15181 gtctggagcg cgtgaaagat cgcatccttg agtaccttgc ggttcaaagc cgtgtcaaca
    15241 aaatcaaggg accgatcctc tgcctggtag ggccgccggg ggtaggtaaa acctctcttg
    15301 gtcagtccat tgccaaagcc accgggcgta aatatgtccg tatggcgctg ggcggcgtgc
    15361 gtgatgaagc ggaaatccgt ggtcaccgcc gtacttacat cggttctatg ccgggtaaac
    15421 tgatccagaa aatggcgaaa gtgggcgtga aaaacccgct gttcctgctt gatgagatcg
    15481 acaaaatgtc ttctgacatg cgaggcgatc cggcctctgc actgcttgaa gtgctggatc
    15541 cagagcagaa cgtagcgttc agcgaccact acctggaagt ggattacgat ctcagcgacg
    15601 tgatgtttgt cgcgacgtcg aactccatga acattccggc accgctgctg gatcgtatgg
    15661 aagtgattcg cctctccggt tataccgaag atgaaaaact gaacatcgcc aaacgtcacc
    15721 tgctgccgaa gcagattgaa cgtaatgcac tgaaaaaagg tgagctgacc gtcgacgata
    15781 gcgccattat cggcattatt cgttactaca cccgtgaggc gggcgtgcgt ggtctggagc
    15841 gtgaaatctc caaactgtgc cgcaaagcgg ttaagcagtt actgctcgat aagtcattaa
    15901 aacatatcga aattaacggc gataacctgc atgactacct cggtgttcag cgtttcgact
    15961 atggtcgcgc tgataacgaa aaccgtgtcg gtcaggtaac cggtctggcg tggacggaag
    16021 tgggcggtga cttgctgacc attgaaaccg catgtgttcc gggtaaaggc aaactgacct
    16081 ataccggttc gctcggcgaa gtgatgcagg agtctattca ggcggcgtta acggtggttc
    16141 gtgcgcgtgc ggaaaaactg gggatcaacc ctgattttta cgaaaaacgt gacatccacg
    16201 tccacgttcc ggaaggtgcg acgccgaaag atggtccgag tgccggtatt gctatgtgca
    16261 ccgcgctggt ttcttgcctg accggtaacc cggttcgtgc cgatgtggca atgaccggtg
    16321 agatcactct gcgtggtcag gtactgccga tcggtggttt gaaagaaaaa ctcctggcag
    16381 cgcatcgcgg cgggattaaa acagtgctaa ttccgttcga aaataaacgc gatctggaag
    16441 agattcctga caacgtaatt gccgatctgg acattcatcc tgtgaagcgc attgaggaag
    16501 ttctgactct ggcgctacaa aatgaaccgt ctggtatgca ggttgtgact gcaaaatagt
    16561 gacctcgcgc aaaatgcact aataaaaaca gggctggcag gctaattcgg gcttgccagc
    16621 ctttttttgt ctcgctaagt tagatggcgg atcgggcttg cccttattaa ggggtgttgt
    16681 aaggggatgg ctggcctgat ataactgctg cgcgttcgta ccttgaagga ttcaagtgcg
    16741 atataaatta taaagaggaa gagaagagtg aataaatctc aattgatcga caagattgct
    16801 gcaggggctg atatctctaa agctgcggct ggccgtgcgt tagatgctat tattgcttcc
    16861 gtaactgaat ctctgaaaga aggggatgat gtagcactgg taggttttgg tacttttgcc
    16921 gttaaagagc gtgctgcccg tactggccgc aacccgcaga ccggtaaaga gatcaccatc
    16981 gctgctgcta aagtaccgag cttccgtgca ggtaaagcac tgaaagacgc ggtaaactaa
    17041 gcgttgtccc cggtggggat gtgacgaagt tcaagggcgc atctactgat gtgccttttt
    17101 tatttgtatt cggtgacttt ctgcgtcttg tgggctgaca attgcccccg tttcttgtca
    17161 caataggcct ttgcgcgcat cgatacgttg cgtgaggtac acagtcatct acagcggagt
    17221 gttgttacac catgatggac agcttacgca cggctgcaaa cagtctcgtg ctcaagatta
    17281 ttttcggtat cattatcgtg tcgttcatat tgaccggcgt gagtggttac ctgattggcg
    17341 gaggcaataa ctacgccgca aaagtgaatg accaggaaat cagccgtggg cagttcgaga
    17401 acgcctttaa cagcgagcgt aatcgcatgc agcaacagct gggcgatcaa tactccgagc
    17461 tggcagcgaa tgaaggctat atgaaaaccc tgcgtcaaca ggtgctgaat cgtctgatcg
    17521 acgaggcgct gttggatcag tacgctcgtg agctgaaact gggtatcagt gatgagcagg
    17581 ttaaacaggc gattttcgcg accccagcct tccaggttga cggcaaattt gataacagcc
    17641 gctataacgg tatcctcaac cagatgggga tgaccgccga tcagtacgcc caggcgctgc
    17701 gtaaccagct cactacccaa cagctgatta acggtgttgc cggtaccgat tttatgctga
    17761 aaggtgaaac cgacgagctg gcggcactgg tcgcgcaaca acgcgtggtg cgtgaggcga
    17821 ctatcgatgt taacgcgctg gcggcgaagc agcctgtgac cgaacaggag attgccagct
    17881 actacgaaca aaacaaaaac aatttcatga cgccggaaca attccgcgtg agttacatca
    17941 agctggatgc cgcaacgatg cagcaaccgg ttagcgatgc ggatatccag agctactacg
    18001 atcagcatca ggatcaattc acccagccgc agcgtacccg ctacagcatc atccagacca
    18061 aaactgaaga tgaagcgaaa gcggtacttg atgagctgaa taaaggcggt gattttgctg
    18121 cattagccaa agaaaaatct gccgatatta tctctgcccg taacggcggc gatatgggtt
    18181 ggttagaaga tgccactatc cccgacgaac tgaaaaatgc tggtctgaaa gaaaaagggc
    18241 aactgtctgg tgtcatcaaa tcttcggtcg gtttcctgat tgtacgtctg gacgacattc
    18301 agccagcgaa agtgaagtcg ttagacgaag tgcgtgacga tgtcgcggcg aaagtgaaac
    18361 acgaaaaagc cctcgatgcg tactatgcgc tgcagcagaa agtgagcgat gcggcaagca
    18421 acgacaccga gtctctggcc ggtgcagagc aagcagccgg cgttaaagcc actcagacgg
    18481 ggtggtttag caaagataac ctgccggaag agttgaactt caagccggtt gccgacgcta
    18541 tctttaacgg cggtctggta ggtgaaaacg gcgcgccagg catcaactct gacatcatca
    18601 ccgtagatgg cgaccgcgca ttcgtgctgc gcatcagcga gcacaaaccg gaagtggtga
    18661 aaccgttggc agatgttcag gaacaagtta aggcactggt tcagcacaac aaagctgaac
    18721 aacaggcgaa agtggatgct gagaaactgc tggttgattt gaaagccggc aaaggtgcgg
    18781 aagctatgca ggctgccggt ctgaaatttg gcgagccgaa aaccttaagc cgttccggtc
    18841 gtgacccgat tagccaggcg gcgtttgcac tgccactgcc agcgaaagac aaaccgagct
    18901 acggtatggc gaccgatatg caaggtaatg tggttctgct ggcgctggat gaagtgaaac
    18961 aaggttcaat gccggaagat cagaaaaaag cgatggtgca gggtatcacc cagaacaacg
    19021 cacaaatcgt ctttgaagct ctgatgagta acctgcgtaa agaggcgaaa atcaaaattg
    19081 gcgatgcgct ggaacagcaa taatcctgaa gccgcctcgc aaaaaaatgc gttgcagctg
    19141 taacaagaaa aggtcgcttt cgcggccttt tccatttctg aacattgcca tttgtttact
    19201 gttttcactg ccgttaaggt gattccactg ttaacaaaca aggagaaaac agtatgaaac
    19261 acggaattaa agcactgctc attaccctgt ccctggcctg tgccggaatg tctcatagcg
    19321 cgctggcggc agcttctgtg gcgaaaccga cggcggtaga aaccaaagcg gaagctcctg
    19381 cagcacaaag taaagcagca gtaccggcga aagccagtga cgaagaaggc acccgggtca
    19441 gcattaataa tgccagcgcg gaagagctag cccgcgcgat gaatggcgtt ggcctgaaga
    19501 aagcgcaggc gattgtcagt tatcgcgaag agtacggtcc gtttaaaacg gtggaggatc
    19561 taaagcaggt gccggggatg ggcaattcgc tggtggaacg taatctggcg gtattaaccc
    19621 tgtaattaat ttgcatagtg gcaatttttt gccagactga agaggtcata ccagttatga
    19681 cctctgtact tataacaaca acgtaaggtt attgcgctat gcaaacacaa atcaaagttc
    19741 gtggatatca tctcgacgtt taccaacacg tcaacaacgc ccgctacctt gaatttctcg
    19801 aagaagcccg ctgggatggg ttggaaaata gcgacagttt tcagtggatg acggcccata
    19861 acatcgcctt cgtcgtggtc aatatcaata ttaactatcg tcgcccagcg gtattaagcg
    19921 acctgttaac tattaccagt cagttgcagc aattaaacgg taaaagcggc atcttaagcc
    19981 aggtcattac actggagccg gaagggcagg tggtagcgga tgcgcttatt acgtttgttt
    20041 gtattgatct taaaacgcag aaagcattag ctctggaagg ggaattgcgc gaaaagctgg
    20101 agcagatggt taagtaaacg ttttgtggtg ccggatgctc aagccgcatc cggcgacacc
    20161 cggaataatt acctcaaccc ggttttctgc ttcatcgctg ccatcaccgt cggtttatcg
    20221 gccagataat gattcaaacc gttggcgcgt aaattacatg ccgcacaatg accgcaaccg
    20281 tcgcctttaa tgccgttata gcaggtcaac gtttcgttac ggactaaatc cagtttgccg
    20341 taataatctg ccagcgccca ggtttccgct ttatcaatcc acatcagcgg cgtttcaaaa
    20401 cgaatatctt tcgccatgcc caaactgacg gcatggttta gtgctttcac aaactcatcg
    20461 cggcaatccg ggtagccgga gaaatccgtt tcacagacgc cggtaattac ggcttctgct
    20521 tttacctgat acgcatatat tgccgccagc gtcaggaaca aaatattacg ccctgggaca
    20581 aacgtattcg ggatgccatc ggcttcaggt tcataatcag gcaccggaat gctgtcacgt
    20641 gtcaggctgc tgaccgccag ctcgttgagc agcgttacat caagaacctt atgcgcgcgt
    20701 gctcccagtt tcagcgccag ttcgcgtgcc acgtcgattt ctgcgcgatg tcgctgaccg
    20761 taatcgaacg tcacgcaatg gacttcatca tattgttgta atgcctgcac cagacaggtg
    20821 gtggaatcct ggcctccact gaacacaacg acagcacgtt tcatagataa tcctgcttga
    20881 acaataaaag cgttatggta acgcctgcga ttaacccgga ccagctattc attgcgacgg
    20941 cgcgggaagc caggcttcgg taaattcaaa ccagccgcgc ggtgtcagtc gcacaccgtt
    21001 cacgccggga ggggcactaa tgcgatagtg atagttgaac agcggcgtca gcgtcgcgtc
    21061 tgccattaac tggctaaaaa ccgctttcag ggcattaaat cggttttcct catcaggcat
    21121 tacttgcacc gcgtccagcg tcgattgcag atgtgcatat gctggagcgt cgaaaacatg
    21181 tggccatagt ggatcgcaac gtagccattg ctccagagta tattccggtg cttcgccaat
    21241 taatctgtcg cccatcatga ggtctgcgtg tgccagtagg gtcgtgtcgt cccagttttt
    21301 tgcgttatga aaaataattg tgagttcaca gccttccgct gccagtgtcg cctgtaggcg
    21361 ttctgccatg gtatgaagtt ctatcggtaa gtgataaacc agcgtcaagg ttttcggtag
    21421 tttgacttca tccggtactt gccagtgcgg aatagtccag cctggcagta atgcatgact
    21481 ggcggtgatc aggttttctc cgacttctaa cgtttgtaat aaaccggatt gatgaataat
    21541 ggagatcact tttcgcgcct gccagaggga gagtcgggga cttttgcgca acgttaaata
    21601 gcaaaaacct aaactgatgc cactactgac ctggctgacc cgttgcagct cctccggttt
    21661 gccgatggtg atttgcacgg gatgccgaca actggttccc aaatcttttt cgaaaagcgg
    21721 cggagttatc cagtactcaa ccgctttaag cagcggatga cgcaaatggt aataatcatg
    21781 gctctccagg cgcaccagct ccgctgtgaa ttgtgttaag cgaaaaggac cagtgccgat
    21841 cagtgggaat tgcggatgcg ccagatggct gcaatagctc gccagccggt gcgcaagcca
    21901 gtaatcgggg cgatgtaaaa agaaggtcag acactgcgga tgggtgactt caatacgctt
    21961 cacgctaata aataattgat ccagtgctgg cagttgtaac agcatcaata atcgctggtg
    22021 taagtgtgag gcttttactg catcgccgtt atgccagtgt agggttgaac gaagataaaa
    22081 gtcccagcgt aacccgtcag tagaggtttc ccagtgatgc gctaaatcgc caatcgggcg
    22141 ctgagtatta ttatcgaagc gggtcaggcc ggaaaatatc tgcccggcga gatgctgctc
    22201 ggcacggccg ggcaaaaagc ctggttgtag cggttcgagc gggcgatagt agggaatacg
    22261 caacgtgggt gtatcgtttt gccattgtcc gcccataaac ggctgtaaca gagtgcgcag
    22321 ctcacctggg gccagttgcg ccagctccag cacatcttgc tgctttccgg tttccagtgc
    22381 ctgttccatc atcgcattgc gtagcgattc cggcgtgacc agaaagcgta attgtccgcg
    22441 ctttccgcgt cctgactgcg cctgccactc cagccatccc gcctcctgtg cctgacgcaa
    22501 cagcgtacga acatggcgtt cgctgcaaaa acagcgttcg gccagttcgc tgacggtgac
    22561 ggtttgcggc tttccggctg aaggttgcca cagacgttga tactggttaa gacggttgag
    22621 caatcgcata taaacccgga acaatattat ttaactattc actattactt ccgtatatat
    22681 caggtgatac tcaatcacca ttaaccgtgt cacagagtgg agaaagaaat ggctcgtctg
    22741 gcagcatttg atatggatgg cactttattg atgcctgacc atcatttagg tgagaaaacc
    22801 ctctctactt tggcgcgact gcgtgaacgc gacattaccc tcacttttgc cacggggcgt
    22861 catgcgctgg agatgcagca tattctcggg gcgctatcgc tggatgcata tttgattacc
    22921 ggcaacggaa cgcgcgtgca ttctctggaa ggtgaacttt tacatcgtga tgatttacct
    22981 gcggatgtcg cggagctggt gctgtatcag caatgggata cccgagccag catgcatatc
    23041 ttcaatgacg acggttggtt taccgggaaa gagatccctg cgttgttgca ggcatttgtc
    23101 tatagcggtt ttcgttatca gataatcgat gtcaaaaaaa tgccactcgg cagcgtcacc
    23161 aagatctgct tctgtggcga tcacgacgat cttacacgct tgcagatcca gctatacgaa
    23221 gcattaggcg agcgtgcaca tttgtgtttt tccgccacgg attgcctcga agtgctgccg
    23281 gtgggctgca ataaaggcgc tgcattgacg gtgctgaccc aacatttagg tttatcgttg
    23341 cgcgattgca tggcctttgg tgatgcgatg aacgatcgcg aaatgttagg cagcgtcggt
    23401 agcggattta ttatgggcaa tgcgatgccg caactgcgcg cggagctccc gcatttaccg
    23461 gtgattggac attgccgaaa tcaggctgtc tctcactatt tgacgcactg gctggactat
    23521 ccacatctac cttattcccc cgaataacga gatcccttcc agcaccgggc aattgcccgg
    23581 ttttttttgc gttgagtttg tcattttgtg ccatggtgtt taaaccgcac agaataaatt
    23641 gtcgcgattt cacctttaaa atagaattaa aagagaaaaa aattctctgt ggaagggcta
    23701 tgttagataa aattgaccgt aagctgctgg ccttactaca gcaggattgc accctctctt
    23761 tgcaggcact ggctgaagcc gttaatctga caaccacccc ctgctggaag cgcctgaaac
    23821 ggctggagga cgacggtatc cttatcggca aagtcgccct gctggatccg gaaaaaatag
    23881 gcctcggcct gaccgccttt gtgctgataa aaacgcaaca tcacagcagc gaatggtatt
    23941 gccgctttgt cacggtggtt accgaaatgc cagaagtgct ggggttctgg cgcatggctg
    24001 gtgaatacga ttatctgatg cgcgtccagg ttgccgacat gaaacgctac gacgagtttt
    24061 ataagcgtct ggtaaacagc gtgccggggc tgtcggacgt cacttccagc ttcgcgatgg
    24121 aacagattaa atacaccact tctttaccca tcgaataaat atccagaatc aggtcaggac
    24181 acaacgcgtg cgattatttg ctcaattaag ctggtatttc cgtcgggaat ggcgtcgcta
    24241 tctcggggct gtcgccttgc ttgtcattat cgcgatgctg caactggttc cgccaaaagt
    24301 ggttggtatt gttgtcgatg gcgtgacaga acaacacttt actaccgggc agatcctgat
    24361 gtggatcgcc accatggtgc tgattgccgt tgtggtttat ctcctgcgtt acgtctggcg
    24421 cgtattgctg tttggtgcgt cttatcaact ggctgttgaa ctgcgtgaag attattaccg
    24481 tcagctaagc cggcagcatc ctgagtttta cctgcgtcat cgcacgggtg acctcatggc
    24541 tcgtgcgact aatgacgtcg atcgcgtcgt gtttgccgcc ggagaagggg tgctgacgct
    24601 ggtggattca ctggtaatgg gctgcgctgt gttgattatg atgtctacgc aaattagctg
    24661 gcagttgacc ttatttgccc tgttaccgat gccagtgatg gcgatcatga ttaagcgcaa
    24721 cggcgatgcc ttgcatgaac gctttaagct ggcacaggcg gcgttttcta gtcttaatga
    24781 ccgcacccag gaaagcctca ccagtattcg catgatcaaa gcctttggtc tggaagatcg
    24841 ccagtcggcg ttatttgccg cggatgccga agataccggc aaaaaaaaca tgcgggtggc
    24901 gcgtattgat gctcgtttcg acccgaccat ctatatcgcg attggtatgg cgaacttgct
    24961 ggcgattggc ggcggtagtt ggatggtggt gcagggcagt ttaacgctgg gccagctcac
    25021 cagttttatg atgtatttag gtctgatgat ttggccaatg ctggcgctgg catggatgtt
    25081 taacattgtg gaacgtggta gtgctgcgta cagccgtatt cgcgcgatgc tggcggaagc
    25141 gccggtggtg aacgatggta gcgaacccgt gccggaaggg cgtggcgaac tggatgtaaa
    25201 tattcaccag ttcacgtatc cgcagactga ccatcctgcg ctggaaaacg tcaatttcgc
    25261 cctgaaaccc ggtcagatgc tgggtatttg cgggccgact ggttccggca aaagtaccct
    25321 gttgtcgctc attcagcgtc atttcgacgt cagcgagggg gatattcgct ttcatgatat
    25381 tcctctgacg aagttacaac tcgatagctg gcgtagccgc ctggcggtag ttagccagac
    25441 accgttcctt ttttccgaca ccgtagcgaa caacatcgcg ttgggttgcc cgaatgccac
    25501 ccagcaagag attgagcatg tcgcgcggtt agccagcgta catgacgata ttttgcgttt
    25561 accgcaaggt tacgatacag aggtgggcga gcgcggcgtg atgctttccg gcgggcaaaa
    25621 acagcgtatc tctattgctc gtgcgttatt agtcaacgcg gaaatcctca tccttgatga
    25681 tgcgctttcg gcggtggacg gacgcacaga gcaccagatc ctgcataacc tgcgtcagtg
    25741 ggggcaggga agaacggtaa tcatcagtgc ccatcgcctt tcggcactga cggaagccag
    25801 tgaaattatt gtgatgcagc acggacatat cgcccagcgt ggcaatcatg atgagctggc
    25861 gcaacaaagc ggctggtatc gcgatatgta tcgctatcaa caactggagg cggcgctcga
    25921 cgacgttccg gaaattcgcg aggaggccgt cgatgcgtag ttttagccaa ctgtggccga
    25981 ctctcaagcg tctgttagcg tacggttcgc cgtggcggaa accgctgggg attgcggtcc
    26041 tgatgatgtg ggttgcggca gcggcagaag tcagtgggcc gctgcttatc agctatttta
    26101 tcgacaatat ggtagcgaaa aataacctgc cgttgaaaat ggttgcaggg ctggcggcgg
    26161 cgtatgttgg gctacaactg tttgccgccg ggctacatta cgcgcagtcg ctgctgttta
    26221 atcgggcggc agtaggcgta gtgcaacagt tgcgtaccga cgtgatggat gctgcgttac
    26281 gccagccatt aagcgagttt gatacccaac ccgtcgggca ggtgatttcc cgcgtcacta
    26341 atgacactga agtgatccgc gatctctacg ttaccgtagt ggcaactgtc ctgcgtagcg
    26401 ccgcactggt gggcgcgatg ctggtggcga tgttcagcct cgactggcga atggcgctgg
    26461 tggcgataat gattttcccg gtggtgctgg tggtaatggt gatataccag cgttacagca
    26521 cgccgattgt ccgtcgtgtg cgcgcctatc tagcggatat caacgacggc tttaacgaaa
    26581 tcatcaatgg catgagcgtt atccagcagt tccgtcagca ggcgcgattt ggcgaacgta
    26641 tgggggaggc cagtcgttca cactatatgg ccaggatgca aaccctgcgc ctcgacggtt
    26701 ttctgctgcg tccgctgctg agtctgtttt catcgctcat tctttgtggc ttgttgatgc
    26761 tgtttggctt ctccgctagc ggcaccattg aagtgggcgt gctgtatgcg tttatcagct
    26821 atcttgggcg acttaacgaa ccattaatcg aactgaccac gcaacaggcg atgctgcaac
    26881 aggctgttgt tgctggtgag cgcgtgtttg aactgatgga cggaccgcgc cagcaatatg
    26941 gcaatgatga tcgcccgtta cagagtggca ccatcgaagt cgataacgtg tcatttgctt
    27001 atcgcgatga caatctggtg ctaaagaaca ttaatctctc tgtgccttcg cgtaactttg
    27061 tggcactggt cgggcatacc ggcagtggca aaagcaccct cgccagttta ttgatgggct
    27121 attacccgct aacggaaggt gagattcgcc ttgatggtcg tccattaagt tcgctaagtc
    27181 acagcgcgct gcgccagggc gtggcaatgg tgcagcaaga tccggtggtg ctggcggata
    27241 ccttcctcgc caacgtgacg ctggggcgtg atatctccga agaacgcgtc tggcaggcgc
    27301 tggaaaccgt gcaactggcg gagctggcgc gcagcatgag tgatggtatt tatacgccgc
    27361 tgggcgagca ggggaataat ctctccgtcg ggcaaaagca actgctggca ctggcacgcg
    27421 tgttggtgga gacgccgcaa atcctgatcc ttgatgaggc aaccgccagc attgactccg
    27481 gtactgaaca ggcgattcaa catgctctgg cggctgtgcg tgaacatacc acgctggtgg
    27541 tgattgctca ccgcttatcg accattgttg atgccgacac cattctggtg cttcatcgtg
    27601 ggcaagccgt ggagcagggc actcaccagc aactgctggc ggcccaggga cgctactggc
    27661 agatgtatca actgcaactt gcgggcgaag agctggcagc cagcgtgcgt gaagaagaat
    27721 cattgagcgc ctgaatagcg caatatttca tcgttggtgc aaaaatgtaa cgcactgtgc
    27781 actgtcatag tgcgttttca ttttcaatct tcttaacttc ctgctctctt tctcgttttt
    27841 catttctggc acaccgcttg caataccttc ttcgtgtagc agaaccatta ccgaattctg
    27901 accggagggg atctatgaag ctggtgaccg tgataatcaa accattcaag ctggaagacg
    27961 ttcgtgaagc gttatcttcc attggtattc agggcctgac cgtcaccgaa gtgaaaggtt
    28021 tcgggcgtca gaaagggcat gccgagctgt accggggggc ggaatacagc gtcaacttcc
    28081 tgccaaaagt aaaaattgat gtggcgattg ctgatgacca actcgatgaa gtgatcgata
    28141 tcgtcagtaa ggcggcttac accggaaaaa ttggcgacgg caaaatcttc gtcgctgaat
    28201 tgcaacgcgt cattcgtatt cgtaccggcg aagccgacga agcggcgctg taatctctgg
    28261 cacacagcaa caggaacgaa aaatgaagat agcgacgata aaaactgggc ttgcttcact
    28321 ggcgatgctg ccgggactgg taatggctgc acctgcggtg gccgataaag ccgacaatgc
    28381 gtttatgatg atttgtactg cgctggtgct gtttatgact attccgggga ttgccctgtt
    28441 ttacggtggg ttgattcgcg gcaaaaacgt gctgtcgatg ctgacgcagg tgacggtgac
    28501 gtttgcactg gtctgtattc tctgggtggt ttacggttac tcgctggcgt ttggtgaggg
    28561 caacaacttc ttcggcaaca ttaactggtt gatgctaaaa aacatcgaac tgacggcggt
    28621 gatgggcagc atttatcagt atatccacgt ggcgtttcag ggctcgtttg cctgcattac
    28681 cgtcggcttg atcgttgggg cgctggcgga acgaatccgc ttctcagctg tgttgatttt
    28741 cgtggtggta tggctgacgc tctcttacat tccgattgcg catatggtgt ggggcggtgg
    28801 tttgctggct tctcacggtg cgctggattt cgcgggtggc acggtggtgc atattaacgc
    28861 cgcaatcgcc ggtctggtgg gcgcgtatct gataggcaaa cgcgtgggct tcggcaaaga
    28921 ggcgtttaaa ccgcacaacc tgccaatggt cttcaccggt actgccattc tctatattgg
    28981 ttggtttggc tttaacgccg ggtcagcggg cacggcgaat gaaatcgcgg cactggcatt
    29041 tgtgaatact gtggtcgcaa cggcggcggc aattcttggc tggatcttcg gtgaatgggc
    29101 gctgcgtggt aagccttctc tgctgggagc gtgttctggc gcgattgccg gtctggtcgg
    29161 cgtgacgcca gcgtgtggct acattggggt tggcggcgcg ttgattatcg gcgtggtagc
    29221 tggtctggcg ggcttgtggg gcgttactat gctcaaacgc ttgctgcggg tggatgatcc
    29281 ctgcgatgtc ttcggtgtgc acggcgtttg tggcattgtc ggctgtatca tgactgggat
    29341 ttttgccgcc agttcgctgg gtggcgtggg cttcgctgaa ggtgtgacga tgggccatca
    29401 gttgctggta cagctggaaa gcatcgccat tacgatcgtc tggtccggtg tggtggcatt
    29461 tattggctac aaactggcgg atctgacggt tggtctgcgt gtaccggaag agcaggagcg
    29521 agaagggctg gatgtcaaca gtcacggcga gaatgcctat aacgcgtaac aagcactgca
    29581 aaaaatagcc ggacggtttt acctccggct atttttttaa ttgtgattac gcatcacccc
    29641 ttcctgaacg gtcgaggcaa ccagcacgcc gtcctgggta taaaactcac cgcgcacaaa
    29701 gccgcgtgcg ctggacgccg aggtgctctc cacgctatac agcagccatt cattcaaatt
    29761 aaacgggcga tggaaccaca tggaatggtc aatggtggca atctgaatcc ccggttcgag
    29821 aaaaccgatg ccgtgcggct gtagagctac cggcaggaag ttaagatcag aagcgtaacc
    29881 gagcagatac tgatgaacgc gcaggtcatc cggcacgcta ccatttgcgc ggatccacac
    29941 ctgacgatgt ggttctgcga cgtgaccttt cagtgggtta tgaaactcca ccggacggac
    30001 ttccagcgga cgatcgcaga tgaatttatc tttaagcact ggcggcagca ggtgcgccag
    30061 cgattgggcg atttgcgttt ccgaaggcag gccatcaggc gctggcgcgg acggcattgt
    30121 tttttgatgt tcgaaacccg cttctggtgc ctggaaagag gccgtcatat aaaaaatcgg
    30181 tttgccgttt tgaatagcag caacccggcg ggcgctgaag ctgttaccgt cacgcagcgt
    30241 ttcgacatca taaataatcg gcttcttact atcgccaggg cgaagaaagt agctgtgaaa
    30301 cgaatgtacc agccgctctt cagggacggt ctcttttgca gcatacaagg cctgacccac
    30361 gacctggccg ccaaacacct ggcgtaaacc taaatcttca ctctggccgc gaaagagtcc
    30421 ttcctcaatt ttttccagat ttaacaatgt cagtaaattt tttagcgcct gactcatata
    30481 actctccagt aacaaagctg ccgcagcaag ccaaagtgag ttgagtataa cgcaaatttg
    30541 ctactggtcc gatgggtgca atggtctgaa ttacgggcta attacaggca gaaatgcgtg
    30601 atgtgtgcca cacttgttga cgttactatt ttgttaacca ctcttccggc gaggaaagtt
    30661 agcccgctgg tgcattgata ataaggagaa atgaatgaaa ctcgtgcaca tggccagtgg
    30721 tttagcggtt gcgattgcgt tggcggcttg cgcagataaa agcgcggata ttcagacgcc
    30781 agccccggct gcaaatacat ctatttcagc aacacaacaa cctgctatcc agcaaccgaa
    30841 tgtctccggt accgtctgga tccggcagaa agtcgcactg ccgcctgatg ctgtgctgac
    30901 cgtgacactt tctgacgcgt cgttagccga tgcaccgtca aaagtgctgg cgcagaaagc
    30961 ggtgcgtacc gaaggtaaac agtcaccatt cagctttgtt ctgccattta atccggcaga
    31021 tgttcagccg aacgcgcgta ttctgttgag tgcggcgatt accgtgaatg acaaactggt
    31081 atttatcacc gataccgttc agccggtgat caaccagggc ggaactaaag ccgacctgac
    31141 attggtgccg gtacagcaaa ccgccgtgcc ggttcaggcc agcggtggtg caacgactac
    31201 cgtaccttcg acttcaccaa ctcaggtgaa tccgtcttcg gcagttccag ctcctacgca
    31261 atattaagcg acgttaaccc tctccgcccg gagagggtta gtagttccag cgataacgct
    31321 gcaagtcgat ttgcccgctt cccgatacca tcacaccttc tgccagtaat gcctgtcgct
    31381 gacgctgtaa atccggtccg gttagcgaaa ttgtgccgtg gcgattaacc acccggtgcc
    31441 agggtaaggt gctgccttca gggagacgct ttaacacacc gcccacctgg cgcgcggcgc
    31501 ggggcgatcc cgccagtttc gccacatcac cgtaagtggt gacatagcct tcgggaatag
    31561 cggcgacgat ttgccagacg cgttggggaa atgaatcttc tttttccatc ttttcttcct
    31621 gaggtaattt ttcagcataa tctggaaaaa cgcccgagtg aagtcgcatt gcgcaagaaa
    31681 ccagcatctg gcacgcgatg ggttgcaatt agccggggca gcagtgataa tgcgcctgtg
    31741 cgttggttct caacgctctc aatgggggct ctgttggttc tcccgcaacg ctactctgtt
    31801 taccaggtca ggtccggaag gaagcagcca aggcagatga cgcgtgtgcc gggatgtagc
    31861 tggcagggcc cccacccatt tctgcctccc accgtttcgt caaaaaaccc caacatggct
    31921 aaactttaac cacaactgac gtcgcaagaa ttgtctggct gcgcagtacg cttcggaggt
    31981 atgtctgatg aagtatgttg atggttttgt ggttgccgtt cctgccgata aaaaggatgc
    32041 ctatcgggaa atggccgcta aggctgcgcc attgtttaaa gagtttggcg cgcttcgtat
    32101 tgtcgaatgc tgggccagcg atgtaccgga tggcaaagtg accgattttc gtatggcggt
    32161 gaaagcggaa gagaatgaag aggttgtctt tagctggatt gaataccctt caaaagaggt
    32221 ccgcgacgct gctaatcaaa agatgatgtc ggacccacgg atgaaagagt tcggcgagtc
    32281 catgccgttt gacggcaagc gaatgatcta tggcggattc gagtcaatca tcgacgaata
    32341 ggtagcgtga cgggctgtgc ggcgtgccgt cagcccaaaa attcacaaat gttgctcggc
    32401 ccagcgtaag aaatcttctt tcggtaatgc cttgctgtag agccagccct gaccgtagtg
    32461 cacgccatgc tggcgtagcc actcttcttg tttactggtt tcgattccct ccgctaccat
    32521 tttcagtttc agtgtttttg ccatttcgat gatatgcggc gtgacatttt tatattccag
    32581 cgcatcaacg aaagatttat cgatcttcag aatgtcgaca tccagatcct gtaaataact
    32641 taaacttgaa tatcccgtac caaaatcatc aagataaatt tcatggcccg cctcccggta
    32701 gcgagaaatt atcggggcgc tggttttcgg atcggcaaac tcgcgttcag tgagttcaag
    32761 cgcgatctgt ctgggattaa cctgatagtg attgatcatt tcacgcagca attgcgggat
    32821 tttttccgag gtgagcacgg tggattcaag attgatcgaa atatgctgct gtggatgctg
    32881 acgcagccag tcgcccatat cttcaaagac gcttcttata atcagtagcg tcaatggctc
    32941 agaaaggccc gtttgctgtg ccagcggaat aaaactatct ggtgacaacc aactaccgtc
    33001 tgtctgcggc cagcgcgcca gtgcctcagc accgacaatt ttgccattgg ctaaggagac
    33061 aatcggctga tagtgcacgc aaatatcacg attttcgata gcatcctgca gccgatgatg
    33121 cggtgactgg atacggcgca aaatacgcag cacaaacatc gctgccagca ggccaatcac
    33181 caacccgagc ggtaaccaaa taaagacttg ccgatgccag cctttctgca acattttcgt
    33241 tgaagcccag gtgatgatcg aaatattcat ctccgggaag ggcaggatat cgtaaatgat
    33301 tccattattt tcgatatgct caccgggtgt tttttgtagc ctggtaataa ttccctgagc
    33361 aatttcatcg ctgctggtta tgacaacgtt atgggcattg ccaataatgg cggcatcaat
    33421 ttgccatgag ctatagggaa tgacatcaat aaaggaagcg gggtcgatca tgacgacata
    33481 atgtgccgtt cccatggcga ccatgtaacg gataatgcct aaatcgttat gcgatgttaa
    33541 ccagacacga taaccatctt tcgaaatttt acctggctcg gggaaggtat cgggcggact
    33601 ttcatgctcc agagacgaac actggggaac gttgttatcg atataaacca cttcctgaat
    33661 atagcgataa ctgtaagata cccgacgcat ttccatgaga tgggcttcgc tacaggcagc
    33721 gccttgccat ctttccagct cttgcagcgc atctttccct tgtgtcgcca ccttattggc
    33781 ccgaatagcg acgcgggagg aataggtatc cagctcttca ataaacgatg tttctacctg
    33841 ctgatgggcc agccagatgc ttaagccgac aggcagcaat actgaaagaa tcagtactcc
    33901 cgaaataagg ccgaccagat gtcgtgttct caccagcata tccttattaa cacagtgtag
    33961 ggaaagtata tctgattgtg gaaaaaggct ggcaggagat aaggaggtag agctggtatt
    34021 tcatgaagtg atgggtggaa acgatcattg tcatttgacc aggcgcagag ctttacgcct
    34081 ggtatgtaac cctaacttaa gatgttgatt cggcgcgagc gagggtaaaa atatcgtaaa
    34141 aagacagttc acctttacgg acgatcattt tttgcagttg ttccttatga acatccgcga
    34201 cacgcggaga gttcaagatg gcttcaacca gcgcggcagg tacaaagcgc gtgttgtacc
    34261 attcgccgtt atagcaaacg cggaaatcca gcacgtcgat atcttcataa cggtagcgtg
    34321 ggtagacatc gaaaaagaag aaaccattaa gcaggataaa taatacaacc agtagccaga
    34381 cagagcctga cagcgtttcg gactgcaaca tcaccgccag ggtggcaaaa aaagcaacgt
    34441 acataccgat aaacagcccc ggatgtttac ggataaaact gatactaaag cggggtttgt
    34501 tgtcgcgttt ttcgcgggta ttcagagact caatcgtttc ggtcagcagg cgttgtattt
    34561 cggtcatcgt ttgccttcgt ggtatctgca actttccagg gaacacccta ttttaacgtg
    34621 ggaatagtag aggggaagta acagatttac cacaattttg cataacagtt gcgaaaaacc
    34681 gattacaatt ttttaattat tctggctgga ttaccgccca cgacaacgtt gttcgggaca
    34741 tcttttgtga caactgcacc tgaggctacc acgacgttat caccaatggt cacaccaggg
    34801 ttaatgaccg cgcgtccgcc aatccagacg ttattaccga tggtgacggg tttccccagt
    34861 tcagcaccgc tattacgtgc tacagggtcg atgggatgtg ttgccgtgta gatatgaacg
    34921 cctggtgcca acatacagtt atcaccgatg cgaatagggc agacatcaag catcacgcaa
    34981 tcgaagttgg cgaaaaaatt attaccgaga aaaatgttat agccatagtc acagcgaaac
    35041 gttggctcaa tataagcctc tgtcacctga ccgaatagat cagcgagaat ttgctggcgt
    35101 aatgtgtgct cttccgccag ggaatgattg tatcggtgaa taagctgacg agcgcgcagg
    35161 cgatcgcgag ataacgtctc atctgccgag cgatacaact caccagcaat catcttttct
    35221 ttttctgtgc tcattactga cctccggttg ctgaaaatgc ggcaacacag taagacgaaa
    35281 agtcagtgaa gagaacgttc ccattacatc tgtgtgataa agatcacata gggtatgtct
    35341 tcatggcgaa aaagtataaa attcttaata aacagccggt tatagctccg aaagcgaatt
    35401 atttattagc gaataaattt ccatactgag gaagggatct tgtcgtacag tttattcatg
    35461 gtcaattcgg cgaggcggtg atctgcggct gagtaaaata ccgccagttc attatctgat
    35521 aattcgtatt tatttttctc gataacacgc tccagcgtgt caattgtctg gcaacgacgt
    35581 aaacgcatta aataatcggt tttcgttaaa ggtttttcgg acatacttct acccatggtt
    35641 gtaataattc taacaagata aactcgcagg attctctttc gtcgcattga caaaacaacg
    35701 gaatagtcga ttacctgact tccgccattt ctgaagatcc tgcatattaa taccataact
    35761 actgaacaac ataaaggtgt catccagata ttcgtcgatc tgctcaatga gcttattgtc
    35821 ttcattatac ttaattttgt aattaagtgc gaaggtcgca atatgctcaa tcagttcatt
    35881 caactggagg ttgatcgccg aggttgggtc gttaacccag ccatgattgc tttcttcaag
    35941 gtttgcaagg cagtcatgat acagggtttc acagagaaac ttaagctgtg cgatatcatg
    36001 tcttttgggt gagtattcat ccataacgcg tccccttctt agcggttgaa ctaacggaca
    36061 cctttcggga tggaaaaaac ttactgacct ggacttgccc tctcgtttgt tagcttaact
    36121 ataagccact ctttgcaggt tttcatcgca ttattacgaa aaattacaat taggaaggaa
    36181 tcgggacagg actcactttt tcatactagc actaacccgc agcaggtaaa agcagtctgc
    36241 tcgaactgtt cataacattt caggattatc gccagatgaa attggtgaca ctaataccag
    36301 gattgctctg aatatgacgt aataaccgag gaatgaataa agaattaccg caaataatta
    36361 agaatagcct ctaaatgatt atggattatt aaatctatta gcgctactta atataaatta
    36421 actaacaatc agtatttttt atgaatttta tccgtggtta atactggttt tcgtatgaga
    36481 tcctgagttg gtggttcaat tactccttaa tgttcgtagg ttatgcataa aaaaggccgc
    36541 ttgcgcggcc ttagtgatta cacgttgtat caatgatgat cgacagtatg gctgtgctcg
    36601 atatcttcat tcttgcggct aaagcggcgg cgaaccacaa caaagaatac cggaacgaag
    36661 aagattgcca gtaccgttgc ggtcaccatc ccgcccatta caccggtacc tactgcgttc
    36721 tgcgcgccgg aaccagcacc agtactgata accagcggca taacgccgag gataaacgcc
    36781 agcgaggtca tcaggatcgg acgtaaacgc atccgcactg catcaagcgt cgcttcaatc
    36841 agacctttac cttctttatc catcaagtct ttggcgaatt cgacgataag tatcgcgttc
    36901 ttcgccgaca acccaatggt tgtgagcagg cctacctgga agtaaacgtc attggtcagg
    36961 ccacggaagg tggcagccag caacgcaccg ataaccccca gcggaacgac cagcataacg
    37021 gagaacggaa tcgaccagct ctcgtacagc gccgccagac acaggaatac gacaatcaac
    37081 gaaatcgcgt acagtgaagg tgcctggttg ccggagaggc gttcctgata ggacatcccc
    37141 gtccagtcat agccaacacc ggtaggcagt ttgctcgcca gttgttccat tagctccatt
    37201 gcttcaccgg tacttttacc cggtgccgcc tggcctaaga tttccatgga tggcaggcca
    37261 ttgtaacgtt ccagacgcgg cgaaccgtac tcccaacgag aagaggagaa tgccgagaac
    37321 ggcaccatct gaccatcagc agcacgaaca taccagtcgc cgatatcatc cggcagcata
    37381 cggtatttcg cttctgacat gacgtaaact ttcttcacac gaccgcggtc gataaagtcg
    37441 ttcacatagc taccgcccca tgcagcgccc agagtggtgt taatgtcgtt gatagaaaca
    37501 cccagcgcct gcgctttttc ctggtcgata tcaatcttaa actgcggggt atcttccaga
    37561 ccgtttggac gtacgctggt cagcatatca gggtgcttcg ctgcttctgc aagcagctgg
    37621 ttacgcgcct gagtcagttt ttcgtgacca aggccagcct ggtcaatcag ctcaaagtca
    37681 aagccggttg cagtacccag ttccacgatt gcgggcaggt taaaggcgaa aaccatcgca
    37741 tctttgattt gcgagaaagc gcgtgttgca cgcatggtaa tcgcttcaac tttgttttct
    37801 tcgcccggac gatcggccca gtccttcaag gaaacgaacg caataccggt attctgacca
    37861 cgtcccgcaa agccgaagcc gttaacggcg aacaccgact caacgttgtt cttttctttg
    37921 gtcagatagt aatgcgttac ctcattgagc actttctgcg tacgttcctg cgttgcacct
    37981 gctggcagct gaaccatggt cataaatacg ccctggtcct catctggcaa gaaggagctt
    38041 ggcagacgca cgaacagata ggccatgccg accacgatga tcagatacag caccaggtaa
    38101 cgccccgtac tgcgcagaat accgcctacg ctgtcggtgt agtggtgcgt gctcttctcg
    38161 aacatgcggt taaaccagcc gaagaagcct tttttacctt ccccgtgatc gcctttggca
    38221 atcggtttca gcatggtggc acaaagagcc ggagtcagga tcaacgctac cagtaccgac
    38281 agcgccattg ctgaaacaat ggtaatagag aactgacgat agatagcacc agtagaaccg
    38341 ccaaagaagg ccatcggtac gaataccgcc gacagtacca tcgcgatacc gaccagagcg
    38401 ccctgaatct gccccatcga cttacgggta gcttcttttg gcggcaaacc ttcttccgcc
    38461 ataacacgct ccacgttttc taccacaacg atagcgtcat ccaccaacaa gccgatagcg
    38521 agcaccatcc cgaacattgt tagcgtgttt atcgagaagc caaaggcggc aaggacggca
    38581 aaggtcccga gcaataccac cggtacggca atggtcggaa tcaacgtcgc gcggaagttc
    38641 tgcaggaaca gatacataac caggaacacg aggatgatcg cttcgaccag cgttttaacc
    38701 acttcgtgaa tagagatttt cacgaacggc gtggtgtcgt acgggtaaac aattttcaga
    38761 cccgacggga agaacggttc catcttcgcc agttcagcac ggattgccgc agcggtatcc
    38821 agcgcgtttg caccggtcgc cagcttgatc cccagaccgg aagccggttg gccgttaaac
    38881 tctgcgatga tgtcgtagtt ctcaccaccc agctcaatct tcgccacatc acgcagcagt
    38941 acgcgggaac catcttgatt cactttcagc aggattttgc cgaactcttc agtagaggtc
    39001 agacgcgtct gagcaataat agaggcgtta agctgttggc ctttcaccgg cggcgtacca
    39061 ccgagctgac ccgccgcaac ctgggcgttc tgcgctttga tggcggtaat gacatcaacc
    39121 ggcgttagct ggaatttgtt cagctcattc gggttcatcc agatacgcat cgcgtactgt
    39181 gaaccgaaca actgaacatc acccacgccc gacgtacggc tgatggcatc tttcatattc
    39241 gccgctacgt agtcagagat atcctcctgc gtcatggtgc catcggtgtt gataacgccg
    39301 acaaccatca ggaagctgct ggatgatttc tcaacgctca ccccttgctg ctgaacttct
    39361 tgcggcagca acggcatcgc cagctgcagt ttgttctgca cctgaacctg cgcgatatcc
    39421 gcatcagtac cagactcaaa ggtcagggtg atctgcacgg tacccgtgga gtcactgtta
    39481 gaggacatgt acatcaggtt atcgataccg ttcatattct gttcgataac ctgtgtcacc
    39541 gtgtcctgca ctgttttcgc atcagcgccg gggtaggagg cggagatcgt tactgccggc
    39601 ggtgcaatcg taggatattg cgccaccggc agtttgagga tcgccagccc ccctgccaac
    39661 atgatgataa tggcgatcac ccacgcaaaa atcgggcgat cgataaagaa attaggcatg
    39721 tcttaacggc tcctgtttaa gttaagactt ggactgttca ggctgagcac cgcttgcggc
    39781 ttgctggtta ttatcagcgg taacttcttg tgcttttacc tggacaccag gacgcacttt
    39841 ctgcagccca cttattacta cgcgatcgcc tgctttcaga ccttctgtca ccagccactt
    39901 atcgccaata gcctggcttg caacgatcgg acgggtttcc actttgtcat ccgcgccaac
    39961 taccagtacg gtggcatcac cacgcggcgt acgggttacg ccctgttgcg ggactaaaat
    40021 agcgtttgga ttaagccctt cttccagacg tgcgcgcacg aacatacccg gcagcagagt
    40081 gtgatccggg ttcgggaaga tagcgcgtag ggtgatagac ccagtggtct gatcaacggt
    40141 aacgtcagag aattccagcg taccgtcctg cgggaactta atgccgtcac tggtgatcag
    40201 cgacactttg gctttgccgt tctcttgttt cagcgtgcca ttcgccagtt cctgtttcag
    40261 gcgcaggaag tcgttgctgg actgggtcac atcaacgtag atcggatcaa gttgctgcac
    40321 ggttgccagc gcagtcgcct gaccgttctg taccaatgcg ccttccgtca cgttcgactt
    40381 accaatgcga ccgctaatcg gagaggtgac tttggtgtaa gccagattga tccgcgcagt
    40441 ttcaacggca gctttcgccg cagttaccgc agcattcgcc tgttgcgcat cagccagagc
    40501 ctgatcgtac tcttgcttac tgatgtactg agtaccgagc agtttctgat aacgattcac
    40561 cgtcaattgc gcgatattgg ctgcagcctg ggctttcgcc agatcacctt tcgcactgtc
    40621 gtatgtcgcc tgataggtcg caggatcaat ctgatagaga gagacacctg cttcgatgtc
    40681 gctaccttct ttgaaattac gcttcaggat aatcccgcta acttgaggac gaacttctgc
    40741 gatccggtag gcactggtgc gacccggaag ctcggttgtg atctgcagag gttcagtttt
    40801 gactgttact acgccaacgg cgggcatctg ctggccacct tgttgggcct gtttgtcgtc
    40861 acatcctgtt agggctaagc tgcctgagag catcagaacg accgccagag gcgtaaaccc
    40921 tctgtttttg ttcatatgta aacctcgagt gtccgatttc aaattggtca atggtcaaaa
    40981 gttaataaac ccattgctgc gtttatatta tcgtcgtgct atggtacata cattcacaaa
    41041 tgtatgtaaa tctaacgcct gtaaattcac gaacatatgg cacgaaaaac caaacaagaa
    41101 gcgcaagaaa cgcgccaaca catcctcgat gtggctctac gtcttttctc acagcagggg
    41161 gtatcatcca cctcgctggg cgagattgca aaagcagctg gcgttacgcg cggtgcaatc
    41221 tactggcatt ttaaagacaa gtcggatttg ttcagtgaga tctgggaact gtcagaatcc
    41281 aatattggtg aactagagct tgagtatcag gcaaaattcc ctggcgatcc actctcagta
    41341 ttaagagaga tattaattca tgttcttgaa tccacggtga cagaagaacg acgtcgatta
    41401 ttgatggaga ttatattcca caaatgcgaa tttgtcggag aaatggctgt tgtgcaacag
    41461 gcacaacgta atctctgtct ggaaagttat gaccgtatag aacaaacgtt aaaacattgt
    41521 attgaagcga aaatgttgcc tgcggattta atgacgcgtc gggcagcaat tattatgcgc
    41581 ggctatattt ccggcctgat ggaaaactgg ctctttgccc cgcaatcttt tgatcttaaa
    41641 aaagaagccc gcgattacgt cgccatctta ctggagatgt atctcctgtg ccccacgctt
    41701 cgtaatcctg ccactaacga ataaccctga atctgactcc aggatttttc ctggacattt
    41761 tcgtcgttgc tattctggtt cactgcgtcg tgatattctt gcggtttgac tttttcaggt
    41821 cgttcttcag gttcagaaac cttcattcat catgactatg ttccagtatt acaaacgatc
    41881 acggcatttt gttttttcag catttattgc ttttgttttt gtcttgttat gccagaacac
    41941 ggcgtttgcg cgggcgtcat cgaatggtga tctgccgaca aaagcggacc tgcaggcgca
    42001 acttgactca ctaaataaac aaaaagatct ttctgctcag gacaaactgg tgcagcagga
    42061 tctgacagat acattagcca ccctcgataa aatcgatcgc ataaaagaag agacagttca
    42121 gctacggcaa aaagtcgctg aagcgccgga aaaaatgcgc caggcgaccg cggcgttaac
    42181 agcacttagc gatgtcgata acgacgaaga aacgcgcaaa attctgagta cgctttcgtt
    42241 gcgccagctg gaaactcgcg ttgcccaggc gctggacgat ttgcaaaacg cacaaaacga
    42301 tctggcgtct tataacagcc agctggtttc gttacagacg cagcccgaac gcgtgcaaaa
    42361 tgcgatgtat aacgcttcgc agcagctgca acaaattcgc agtcgtctgg atgggactga
    42421 tgtcggcgag actgccttac gtcccagcca gaaagtgtta atgcaggctc agcaggcgtt
    42481 gctgaatgcg gagattgacc agcagcgtaa aagcctggaa gggaacaccg tcttgcagga
    42541 taccttgcaa aagcaacgtg attacgtgac ggcgaacagc gcccgtctgg agcaccagtt
    42601 gcagctgttg caagaagcgg taaacagcaa gcgcctgact ttaactgaaa aaacggcgca
    42661 ggaagccgtc tccccggatg aagccgcgcg tattcaggct aatccgctgg tgaaacagga
    42721 actggaaatt aaccagcagt taagtcagcg tctgattacc gcgactgaaa acggtaatca
    42781 gttgatgcag caaaacatta aagtcaaaaa ctggctggag cgggcgctgc aatcggaacg
    42841 caatattaaa gagcagattg ccgtcctgaa gggcagcctg ctgttgtctc gtatccttta
    42901 ccagcaacaa caaacgctgc cctcggcgga tgaactggaa aacatgacca accgcatcgc
    42961 ggatttgcgt ctcgaacagt ttgaagttaa ccagcagcgt gatgcactct tccagagcga
    43021 tgcgttcgtc aacaaactgg aagaaggtca caccaacgaa gtcaacagcg aagttcacga
    43081 tgcgttattg caagtggttg atatgcgtcg cgaattgctg gatcaactca acaaacagtt
    43141 gggtaaccag ctgatgatgg ccattaacct gcaaatcaac cagcagcagt taatgagcgt
    43201 atcgaaaaac ctgaaatcca tcctgactca gcaaatcttt tgggtgaaca gtaaccgtcc
    43261 aatggactgg gactggatca aagcgttccc gcaaagcctg aaagatgaat ttaagtcgat
    43321 gaaaatcacg gtgaactggg aaaaagcctg gcctgccgtt tttatcgctt tcctcgctgg
    43381 tttgccgctg ctgttgattg ccgggctgat ccactggcgt ctgggctggc tgaaagcgta
    43441 tcaacagaaa ctggcttccg ctgtgggttc cctgcgtaac gatagccagc tcaacacacc
    43501 aaaagcgatc cttatcgacc tgatccgcgc gctgccggtg tgcctgatta ttctcgcggt
    43561 tggcctgatt ctgttgacca tgcagctcaa catcagcgaa ctgctatggt cgttcagtaa
    43621 aaaactggcg attttctggc tggtgtttgg cctgtgctgg aaggtactgg agaaaaatgg
    43681 cgttgccgtg cgtcacttcg gcatgccgga gcagcagacc agccactggc gtcggcaaat
    43741 tgtccgcatc agtctcgcgt tgctgcctat ccatttctgg tctgtggtgg cagaactttc
    43801 cccgctgcat ctgatggatg atgtgctggg gcaggcgatg attttcttca acctgctgct
    43861 gattgccttc ctggtatggc caatgtgccg cgaaagctgg cgtgataaag agtcgcacac
    43921 catgcgactg gtcaccatta ccgtgctgtc gattatcccg attgcattga tggtgctgac
    43981 tgccacgggt tatttctaca ccacgctgcg cctctccggg cgttggattg aaaccgttta
    44041 tctggtgatc atctggaact tgctctacca gacggtattg cgcggcttaa gcgtagcggc
    44101 gcggcgtatc gcctggcgtc gtgcgctggc gcgtcggcag aatctggtga aagagggcgc
    44161 agaaggtgcc gaaccgccgg aagaacccac cattgcactg gagcaagtta accagcagac
    44221 gctgcgtatt accatgttgc tgatgtttgc gctgttcggt gtcatgttct gggcaatttg
    44281 gtccgatttg atcaccgtgt tcagctatct cgacagcatc acgctctggc attacaacgg
    44341 cactgaagct ggcgctgcgg tggtgaaaaa cgtcaccatg ggcagtctgt tgtttgcgat
    44401 tatcgcctca atggtggcct gggcgttgat tcgcaacctg cctggtttac tggaagtgct
    44461 ggtgctctcg cgactgaata tgcgtcaggg cgcgtcgtat gccattacta ccatccttaa
    44521 ctacatcatt attgccgttg gtgcgatgac ggtgttcgga tcgctgggcg tctcttggga
    44581 taaactccag tggctggccg cagcattatc cgtaggtctt ggttttggtt tacaagaaat
    44641 tttcggtaac ttcgtctccg gtttgatcat tctgttcgaa cgtccggtgc gtattggcga
    44701 tacggtaacc attggtagct tctcggggac ggtaagtaag atccgtattc gtgcgacaac
    44761 gattaccgat ttcgatcgca aagaagtgat catcccgaac aaagcgtttg ttaccgagcg
    44821 tctgatcaac tggtcgttga ctgacactac tacgcgtctg gtgatccgtc tcggcgtggc
    44881 ctatggctcc gatctggaaa aagtgcgtaa agtgttactg aaggcggcga ctgagcaccc
    44941 aagggtgatg cacgaaccaa tgccggaagt cttctttacg gcgtttggtg ccagcacgtt
    45001 ggatcatgag ctgcgtctgt atgtgcgtga actgcgtgac cgtagtcgta ctgtcgatga
    45061 gctgaaccgt actatcgatc agctgtgccg tgaaaacgac atcaacattg cctttaacca
    45121 gcttgaagtg catctgcaca acgagaaggg cgatgaggtg acggaagtca aacgcgacta
    45181 caaaggcgat gacccgacgc cagcggtagg gtaataacca aagggggcga catttagttg
    45241 ccccgagatt actgacaaag tgcgcgttgt tcatgccgga tgcggcgtga ccgccttatc
    45301 cggcctacga aaccgcaaga attcaatgta ttgcaggagc ggtgtaggcc tgataagcgt
    45361 agcgcatcag gcagttttgc gtttgcccac aatcttaggg gacatttagc ggccccattt
    45421 atttctcact tttccgcctc atcatcgcgc gttaatttct tttcataatc gcgttttaca
    45481 atatccagcg cgcgcagcac ggtgcgggct gggatctgat tttcttccag cagcacaatc
    45541 aaatcgacag ccagtttgac atcgtcaggg gcattttcca gtgacatact ctctccattg
    45601 ctagcgggtt aagcgcgcta gcctgttttc gattttttcc agcgcatggc ggcagcgtgc
    45661 caggcgcgct tcataggctt ccacttcacg atgcagcgtt tgctgttcca cgagatcggt
    45721 cacccgcgcc aggcgggctc tgcgttcggc aaccatctca cgtagccgcc gctcaaaatc
    45781 ctgatgctga atacgtttac gctgccagcg ggcaattttc ggtggcgcac tgtcccactc
    45841 gcgcaatgac caggcggagg cttcacgcgc gatggcttcc agttgtgccg ccagatgttc
    45901 cgccagccag gccacttgcg gcagctgttg ctgctcaact gcatgacgaa gcgcagccag
    45961 attatcgccc gcctcatcga gacaagcctg cagtgttgtc gcacgggttt gaaaaaggtg
    46021 tctgtcaaaa cgggcactta gcgtggcaaa ttgcgctacc ggggcacaac gctgacgcag
    46081 cgtagcgagc tgtccttcca gtttttccag cagcagggcg gttttcacga taagacctca
    46141 atgaaaatga taattgttat gctaaagtag ccactctgta agctgacaac actcaatatg
    46201 caacgaatca ttttaatcat cattggctgg ctggcggtag tgctgggtac gctgggcgtg
    46261 gtattaccgg tattaccgac gacgccgttt atcctgctgg cggcctggtg ctttgcccgt
    46321 tcttccccgc gctttcacgc ctggttgctg taccgctcat ggtttggcag ctatctacgt
    46381 ttctggcaga aacatcatgc gatgccgcgc ggcgtcaaac cgcgggcgat tttgcttatt
    46441 ttgctcacgt ttgccatttc tctgtggttc gtccagatgc catgggtgcg catcatgttg
    46501 ctggtaattc tcgcctgttt gcttttctat atgtggcgaa ttccggtgat tgatgaaaag
    46561 caagaaaagc actgaagcac aacaatcgca gttgcaatta ttgcgtacag ccagtacatt
    46621 ctggcgtttt cgagcacagg cgcaggcggt caaaggttaa acaactgtta cttttgatac
    46681 gtttaaaacg cgccgtgagt accaccgtaa caagcaggca tacacttatg accgcgactg
    46741 cacagcagct tgagtatctc aaaaatagca tcaaaagcat tcaggactac ccaaaacccg
    46801 gcattctttt ccgcgatgtc accagcttac tggaagaccc gaaagcttac gctctcagca
    46861 tcgacttgct ggttgagcgt tacaaaaatg cgggcattac caaagttgtc ggcaccgaag
    46921 cgcgtggctt cttgtttggc gctccggtag ctctgggtct gggcgttggc tttgtaccgg
    46981 tccgtaaacc gggcaaactg ccgcgtgaaa ccatcagtga aacttacgac ctggaatacg
    47041 gcaccgatca gctggagatc cacgttgatg ccatcaaacc gggcgacaaa gttctggtgg
    47101 tggacgatct gctggcaacc ggcggcacta tcgaagcgac cgttaaactg atccgtcgtc
    47161 tgggtggtga agtggctgac gctgcgttca ttatcaacct gttcgatctc ggcggcgaac
    47221 agcgtctcga aaaacagggc attaccagct acagccttgt cccgttcccg ggccattaat
    47281 tatcgccagt cttgtgctgc ccacgctacg gacagcacaa gatgtgcatt cagcctcgcc
    47341 gttctgacgg ggctgtgtta gcattacccc ttcgtgaatc caccttccag cgtttcagag
    47401 cctgccaatg agttatcagg tcttagcccg aaaatggcgc ccacaaacct ttgctgacgt
    47461 cgtcggccag gaacatgtgc tgaccgcact ggcgaacggc ttgtcgttag ggcgtattca
    47521 tcatgcttat cttttttccg gtacccgtgg cgtcggaaaa acctctatcg cccgactgct
    47581 ggcgaagggg ctaaactgcg aaaccggcat taccgcgacg ccgtgcggcg tgtgcgataa
    47641 ctgtcgtgaa atcgagcagg ggcgctttgt cgatctgatt gaaatcgacg ccgcctcgcg
    47701 caccaaagtt gaagataccc gcgacctgct ggataacgtc cagtacgctc cggcgcgtgg
    47761 tcgtttcaaa gtttatctga tcgacgaagt gcatatgctg tcgcgccaca gctttaacgc
    47821 actgttaaaa acccttgaag agccgccgga gcacgttaag tttctgctgg cgacgaccga
    47881 tccacagaaa ttgccggtga cgattttgtc gcgctgtttg caatttcatc tcaaggcgct
    47941 ggatgtcgag caaattcgcc atcaacttga gcacatcctc aacgaagaac atatcgctca
    48001 cgagccgcgg gcgttgcaat tgctggcgcg cgccgctgaa ggcagcctgc gagatgcctt
    48061 aagtctgacc gaccaggcga ttgccagcgg tgacggccag gtttcaaccc aggcagtcag
    48121 tgcgatgctg ggtacgcttg acgacgatca ggcgctgtcg ctggttgaag cgatggtcga
    48181 ggccaacggc gagcgcgtaa tggcgctgat taatgaagcc gctgcccgtg gtatcgagtg
    48241 ggaagcgttg ctggtggaaa tgctcggcct gttgcatcgt attgcgatgg tacaactttc
    48301 gcctgctgca cttggcaacg acatggccgc cattgagctg cggatgcgtg aactggcgcg
    48361 caccataccg ccgacggata ttcagcttta ctatcagacg ctgttgattg gtcgcaaaga
    48421 attaccgtat gcgccggacc gccgcatggg cgttgagatg acgctgctgc gcgcgctggc
    48481 gttccatcca cgtatgcctc tgcctgagcc agaagtgcca cgccagtcct ttgcgcccgt
    48541 cgcgccaacg gcagtaatga cgccaaccca ggtgccgccg caaccgcaat cagcgccgca
    48601 gcaggcaccg actgtaccgc tcccggaaac caccagccag gtgctggcgg cgcgccagca
    48661 gttgcagcgc gtgcagggag caaccaaagc aaaaaagagt gaaccggcag ccgctacccg
    48721 cgcgcggccg gtgaataacg ctgcgctgga aagactggct tcggtcaccg atcgcgttca
    48781 ggcgcgtccg gtgccatcgg cgctggaaaa agcgccagcc aaaaaagaag cgtatcgctg
    48841 gaaggctacc actccagtga tgcagcaaaa agaagtggtc gccacgccga aggcgctgaa
    48901 aaaagcgctg gaacatgaaa aaacgccgga actggcggcg aagctggcgg cagaagccat
    48961 tgagcgcgac gcgtgggcgg cacaggtgag tcaactttcg ctaccaaaac tggtcgaaca
    49021 ggtggcctta aatgcctgga aagaggagag cgacaacgca gtatgtctgc atttgcgctc
    49081 ctctcagcgg catttgaaca accgcggtgc acagcaaaaa ctggctgaag cgttgagcac
    49141 gttaaaaggt tcaacggttg aactgactat cgttgaagat gataatcccg cggtgcgtac
    49201 gccgctggag tggcgtcagg cgatatacga agaaaaactt gcgcaggcgc gcgagtccat
    49261 tattgcggat aataatattc agaccctgcg tcggttcttc gatgcggagc tggatgaaga
    49321 aagtatccgc cccatttgat cgtaagcaca gcttacgttc gtcatcctta acgtgattga
    49381 gagagaaacc tatgtttggt aaaggcggtc tgggtaacct gatgaagcaa gcccagcaga
    49441 tgcaagaaaa aatgcagaaa atgcaggaag agatcgcgca gctggaagtc accggcgaat
    49501 ctggcgcagg tctggtaaaa gtgaccatca acggtgcaca caactgccgt cgcgtagaga
    49561 tcgacccgag cctgctggaa gacgacaaag agatgctgga agacctggtg gctgcagcat
    49621 tcaacgacgc agcacgtcgt attgaagaaa cgcagaaaga aaaaatggcc tctgtatcct
    49681 ccggaatgca gctgccgcct ggctttaaga tgccgttctg atgcaaacca gcccgctgtt
    49741 aacacagctt atggaagcac tgcgctgtct gccgggcgtt ggcccgaagt cggcgcagcg
    49801 tatggcgttc acgctgcttc agcgcgatcg tagcggcggg atgcgtctgg cgcaggcgct
    49861 cacccgggcg atgtcggaaa tcggccactg cgccgattgc cgcactttca ccgaacagga
    49921 agtctgtaac atctgttcga atccgcgtcg tcaggaaaac ggtcaaatct gtgtggtgga
    49981 gagtccggcg gacatctacg ccattgagca gacggggcag ttttcaggcc gttattttgt
    50041 gttgatgggg cacctgtcac cgctggacgg catcggtccg gatgatatcg gccttgatcg
    50101 tctggaacag cgtctggcag aggaaaaaat cactgaagtg atcctcgcca ccaatcccac
    50161 ggttgaaggt gaagctaccg ctaactacat tgccgagctt tgcgcgcaat atgacgtgga
    50221 agccagccga atcgctcatg gcgtaccggt tggcggcgaa ctggaaatgg tcgatggcac
    50281 cacgctgtca cactcccttg ccgggcgtca taagattcgt ttttaagcaa acgagagcag
    50341 gatcacctgc tctcgcttga aattattctc ccttgtcccc atctctccct catcctgttt
    50401 ttaaccttaa aatggcatta ttgaggtaga cctacatgaa aggacaagaa actcgtggtt
    50461 ttcagtcaga agtgaaacag cttctgcacc tgatgatcca ttctctctat tccaataaag
    50521 aaatcttcct gcgtgagctt atctctaacg cctccgatgc ggcggacaag ctgcgtttcc
    50581 gtgcgctatc taacccggac ctgtacgaag gtgatggcga actgcgcgtt cgtgtctctt
    50641 tcgataaaga caagcgcacg ctgaccatct ccgataacgg cgtggggatg acccgcgacg
    50701 aagtgattga ccatctgggg actatcgcta aatccggtac caaatcattc ctcgaatccc
    50761 tgggttctga ccaggcgaaa gacagccagc tgatcggtca gtttggtgtt ggtttctact
    50821 ctgcgtttat cgtggccgac aaagtgaccg tgcgtactcg cgcggcaggc gaaaaaccag
    50881 aaaacggcgt cttctgggaa tcggctggcg aaggtgaata taccgttgcc gacatcacca
    50941 aagaagatcg tggtactgaa atcaccctgc atctgcgtga aggcgaagac gagttcctcg
    51001 atgactggcg cgtgcgttcc atcatcagca aatactccga ccatatcgcg ctgccggtag
    51061 agatcgaaaa acgcgaagag aaagacggcg aaaccgttat ctcctgggag aaaatcaaca
    51121 aagcgcaggc gctgtggact cgtaacaagt cggaaatcac cgatgaagag tacaaagagt
    51181 tctacaaaca catcgcccac gactttaatg atccgctgac ctggagccac aaccgcgttg
    51241 aaggtaagca ggagtacacc agcctgctgt acatcccgtc ccaggctccg tgggatatgt
    51301 ggaaccgtga tcataaacac ggcctgaaac tgtacgtcca gcgtgtgttc atcatggacg
    51361 acgcagaaca gttcatgccg aactatctgc gcttcgtgcg tggtctgatt gactccagcg
    51421 atctgccgct gaacgtttcc cgtgaaatcc tccaggacag cacggtaacg cgtaacctgc
    51481 gcaatgcgct gaccaagcgt gtgctgcaaa tgctggaaaa actggcgaaa gacgacgcgg
    51541 aaaaatacca gaccttctgg caacagtttg gcctggtact gaaagaaggt ccggcggaag
    51601 atttcgctaa ccaggaagcg atcgccaaac tgctgcgttt tgcttctact tataccgatt
    51661 cttctgcgca gaccgtgtct ctggaagact acgtttcccg catgaaagaa gggcaggaga
    51721 aaatctacta catcactgca gacagctatg cggcagcgaa gagcagccca cacctggaac
    51781 tgctgcgtaa gaaaggcatc gaagttctgc tgctttccga ccgcatcgat gagtggatga
    51841 tgaactatct gactgagttc gacggtaaac cgttccagtc ggtgtctaaa gttgacgagt
    51901 cgctggaaaa actggctgac gaagttgatg agagcgcgaa agaagcggag aaagcactga
    51961 ctccgttcat cgaccgtgtg aaagccctgc tcggcgagcg cgtgaaagat gtccgtctga
    52021 ctcaccgtct gaccgatacg ccagcgatcg tttcgaccga cgcggacgaa atgagcactc
    52081 agatggcgaa actgttcgct gcggcgggcc agaaagtgcc agaagtgaaa tacatcttcg
    52141 aactgaaccc ggatcacgta ctggtgaaac gtgcggcaga tactgaagat gaagcgaagt
    52201 tcagcgagtg ggtagaactg ctgctggatc aggcgctgct ggcagaacgc ggcacgctgg
    52261 aagatccgaa cctgtttatt cgtcgtatga accagctgct ggtttcctga tgtcatgccg
    52321 gatgaccttt gtgtcatccg gcatttttct tttcatcatc tgcactttcc gcaaattatc
    52381 tcgccattaa ccgtttcagc ctcaggtgcc tttcttgagg caatcgcctg ttggtggtat
    52441 cgtttatcgc tttttcaaaa aattcgacac attttaaggg gattttcgca atgcgtatca
    52501 ttctgcttgg cgctccgggc gcggggaaag ggactcaggc tcagttcatc atggagaaat
    52561 atggtattcc gcaaatctcc actggcgata tgctgcgtgc tgcggtcaaa tctggctccg
    52621 agctgggtaa acaagcaaaa gacattatgg atgctggcaa actggtcacc gacgaactgg
    52681 tgatcgcgct ggttaaagag cgcattgctc aggaagactg ccgtaatggt ttcctgttgg
    52741 acggcttccc gcgtaccatt ccgcaggcag acgcgatgaa agaagcgggc atcaatgttg
    52801 attacgttct ggaattcgac gtaccggacg aactgattgt tgatcgtatc gtaggccgcc
    52861 gcgttcatgc gccgtctggt cgtgtttatc acgttaaatt caatccgccg aaagtagaag
    52921 gcaaagacga cgttaccggt gaagaactga ctacccgtaa agacgatcag gaagaaaccg
    52981 tgcgtaaacg tctggttgaa taccatcaga tgactgcacc gctgatcggc tactactcca
    53041 aagaagcgga agcgggtaac accaaatacg cgaaagttga cggcaccaag ccggttgctg
    53101 aagttcgcgc tgatctggaa aaaatcctcg gctaattcga aagcgcgcac ggacagtccc
    53161 ctcgccccct cggggagagg gttagggtga ggggaacagg cccgcacaag caaacttatc
    53221 agcaatctca ggccggatat tcattcggcc ttttacaaaa acctcaatct gcgctattcc
    53281 tttttctgat ttgacctctc acagcaatta gttcttcttc ctcacttttc cgctacaatt
    53341 atcaacaagt tgaatcgata agaggcggta atgcgtcaga ctaaaaccgg tatcctgctg
    53401 gcaaacctgg gtacgcccga tgcccccaca cctgaagcgg taaaacgcta tctgaaacaa
    53461 tttttaagcg acagacgcgt ggttgatacc tcacggttgt tatggtggcc gttgctgcgc
    53521 ggcgtgattt tgccgctgcg ctcgccgcgt gtggcgaagc tgtacgcctc ggtctggatg
    53581 gaagacggct cgccgctgat ggtttacagc cgccagcaac agcaggcgtt ggcacaacgt
    53641 ttaccggata cgcccgtagc gctgggcatg agctacggct cgccatcact ggaaagcgcc
    53701 gtcgatgaac tcctggcaga gcatgtagat catattgtgg tgctgccgct ttatccgcaa
    53761 ttctcctgtt ctacggtcgg tgcggtatgg gatgaactgg cacgcattct ggcgcgcaaa
    53821 cgtagcattc cggggatatc gtttattcgt gattacgccg ataaccacga ttacattaat
    53881 gcactggcga acagcgtacg cgcttctttt gccaaacatg gcgaaccgga tctgctgctg
    53941 ctctcttatc atggcattcc ccagcgttat gcagatgaag gcgatgatta cccgcaacgt
    54001 tgccgcacaa cgactcgcga actggcttcc gcactgggga tggcaccgga aaaagtgatg
    54061 atgacctttc agtcgcgctt tggccgggaa ccctggctga tgccttatac cgacgaaacg
    54121 ctgaaaatgc tcggagaaaa aggcgtaggt catatacagg tgatgtgccc gggctttgct
    54181 gcggattgtc tggagacgct ggaagagatt gccgagcaaa accgtgaggt cttcctcggt
    54241 gccggcggga aaaaatatga atatattcca gcgcttaatg ccacgccgga acatatcgaa
    54301 atgatggcta atcttgttgc cgcgtatcgc taaagctgag cggtaaagaa ctgagcgccg
    54361 tcgcgaagag cctcgtcggc ggttttcatc attcgtgaat aatgcaaaaa ggcatgcagc
    54421 gtacctgggt agagtttgaa ctcacagggc tgctgatgcg ccgctaacgt ctggtaaagc
    54481 agacggctgt catccagcag cggatcgaac tccgccccgg caataaaaca gggcggaact
    54541 tcgcgagtga gatcattatt aaacagacag taatacggtg actcgcggtc cgcgtcgttg
    54601 cttaaatacg cctcttcata catctgcaaa tcctgttgcg ttaagccatc ccagacaccg
    54661 cccaacagac gacgagtcac ggaatcccgt aatccgtaaa gcccatacca cagcaaaaca
    54721 cccgcaattt taccgcaatc gatctgttta tcacgcaacc acaacgcact ggcgagcgcc
    54781 agcatggcac ctgcggaatc accggcaaag ccaatgcggg acatattgat ttgataatcc
    54841 tccgcctgct ggtggaaata acaacaagca gccacaattt cctctatcgc ttgcggaaaa
    54901 cgcgcttcag gtgaaagggg gtaatcaata ccaatcaccg tacattggct gtagcttgcc
    54961 agcaggcgca tgatgcgatc gtgggtatcg agattgccga gaataaaacc gcctccatgc
    55021 aaataaaata gcgtcgccgg gctatctggc tgcggacaaa agagacgtgt ttccacctgc
    55081 ccatattttg ttggaaccat gtaagctctg gttgccattt ctggagcgcc cgcattccag
    55141 aatcggcgct caagcgtgta atactgtcgt tgctcagcaa tcgttcccgt tgcgggccag
    55201 gacggtaaat ccggctgaag agtattcaca acggtcttca tttcagcaga aataaggtcc
    55261 agaacaggta gtttgttttc cggcttcata caaaaactcc tttcaaatta cgtcattgta
    55321 aggaaccact gccatgaaaa tgcgatcccg cctgctgata ttgaaactgg ctgcgtctcg
    55381 cgcgctcccg tcagattgtg ttaacattcg ccgctcagtt aaccacccgt aaaaacaacc
    55441 atgaaatttc ccggtaaacg taaatccaaa cattacttcc ctgtaaatgc acgcgatccg
    55501 ctgcttcagc aattccagcc agaaaacgaa accagcgccg cctgggtcgt aggtattgac
    55561 cagacgctgg tcgatattga agcgaaagtg gatgatgaat tcattgagcg ttatggatta
    55621 agcgccgggc attcactggt gattgaggat gatgtagccg aagcgcttta tcaggaacta
    55681 aaacagaaaa acctgattac ccatcagttt gcgggtggca ccattggtaa caccatgcat
    55741 aactactcgg tgctcgcgga cgaccgttcg gtgctgctgg gcgtcatgtg cagcaatatt
    55801 gaaattggca gctatgccta tcgttacctg tgtaacacct ccagccgtac cgatcttaac
    55861 tatctacaag gcgtggatgg cccgattggt cgttgcttta cgctgattgg cgagtccggg
    55921 gaacgtacct ttgctatcag ccctggccac atgaaccagc tgcgggctga aagtattccg
    55981 gaagatgtga ttgccggagc ctcggctctg gttctcacct cttatctggt gcgttgcaag
    56041 ccgggtgaac ccatgccgga agcaaccatg aaagccattg agtacgcgaa gaaatataac
    56101 gtaccggtgg tgctgacgct gggaactaag tttgtcattg ccgagaatcc gcagtggtgg
    56161 cagcaattcc tcaaagacca cgtctctatc cttgcgatga acgaagatga agccgaagcg
    56221 ttgaccggag aaagcgatcc gttgttggca tctgacaagg cgctggactg ggtagatctg
    56281 gtgctgtgca ccgccgggcc aatcggcttg tatatggcgg gctttaccga agacgaagcg
    56341 aaacgtaaaa cccagcatcc gctgctgccg ggcgctatag cggaattcaa ccagtatgag
    56401 tttagccgcg ccatgcgcca caaggattgc cagaatccgc tgcgtgtata ttcgcacatt
    56461 gcgccgtaca tgggcgggcc ggaaaaaatc atgaacacta atggagcggg ggatggcgca
    56521 ttggcagcgt tgctgcatga cattaccgcc aacagctacc atcgtagcaa cgtaccaaac
    56581 tccagcaaac ataaattcac ctggttaact tattcatcgt tagcgcaggt gtgtaaatat
    56641 gctaaccgtg tgagctatca ggtactgaac cagcattcac ctcgtttaac gcgcggcttg
    56701 ccggagcgtg aagacagcct ggaagagtct tactgggatc gttaagttat cgaccagacc
    56761 ggacgacgat ggcatccgta ggccggataa gatgcgctag catcgcatcc ggcaataacg
    56821 tcttgtttta ccccgtcacc acctcacctg ccggtggcgt ttccagcaat tccagcatag
    56881 tacgggcaat ttcacgttca cccatcacta cctgattcgc gccacgttcg gtgatatacg
    56941 tcacttcatc gtcataatgg gcgcgggcga taatctcaat atccgggttt ttcgcgcggg
    57001 cagacgccac aatctcaccc gcttcataac cgttggggat cgtcaggatc agccattttg
    57061 cacattccag atgcgccagt tgcataattt cttcgttcgc tgcattgccc aatacagcgc
    57121 ggaccccacg ctctcgcagc tcatcaacac gggttcgtga cgtctcaatc accaccagcg
    57181 gaatatcaga ggcgagcaat ttctccccca gcaggctgcc tacacgaccg taacccacca
    57241 atagcgcatg gttgcaaata tccactggga tctgtttctc ttcttcgatt gcctcttcca
    57301 gcgtctgctc ttccagcgtt tcggtcttcg ccagatattt ctccagtagt gcgaacagta
    57361 ccgggttgag cataatcgac aggatcgccc ctgccagtac caggttttgt ccggcctgcg
    57421 gcagtaaatt caatgccatt cccagtcccg ccaggataaa cgcgaactca ccaatctgcg
    57481 ccaggctggc ggcgatggtt aatgccgtac gttgggagtg accaaacagt cgcaccagga
    57541 aaaatgcggc taacgactta ccaaacagaa taatcgccag cgtcgccagc actgccagcg
    57601 gttgctgaat cagaattaac ggatcaaaca acatcccgac ggagacaaaa aacagcaccg
    57661 caaacgcgtc gcgcaatggc agcgtatcgt gggcggcacg gtgactcagt tcagactcgt
    57721 tcagtaccat cccggcaaag aacgcaccga gtgcaaagga gacatcaaac agctctaccg
    57781 caccaaaggc aatccctaac gccagcgcca gcaccgacag ggtaaacagc tcgcgagaac
    57841 cggttgccgc gctgcgtgcc ataatccacg gcaccagacg gcgacctacc agcatcataa
    57901 tggcgataaa tgcgatcact ttgccgatgg tgatccccat atcgactgca agagtggcaa
    57961 agcccacatc gccctgttcc atcattcctg ccactgcggg cagcaacacc agcgtcagaa
    58021 ccattaccag gtcttccaca atcaaccaac cgatggcgat ttgcccacgc tgactgtcaa
    58081 ttaattgccg ttcttcaagt gcgcgcagta acaccacggt actggcggtg gaaagacata
    58141 aaccgaacac gataccggtc attaacgacc agcccagcac ggcagagagc gccataccca
    58201 gcagcgtcgc cacggctatc tgggcgatcg caccgggaat ggcgatggcc tttaccgcca
    58261 tcaaatcctt cagcgaaaag tgcaaaccga cgccgaacat cagcaaaata acgcccagtt
    58321 cagccagttc cggcgcaagc ttggtatcgg caacaaagcc cggagtgaat ggtcctgcca
    58381 gcacacccgc taacagatat cccaccagag gagaaatacg tagtttattg gccagcatgc
    58441 cgaggataaa ggcgagcaca aggccgccaa caatggtggt gataagcggg gtggcgtgat
    58501 gcattccgtc tccttttcct ggtggttatt gtccattttt ggccggggaa accaaaatta
    58561 caggtaatag tttatgacaa tttcattgat gatgttcatg aataattatt gaattttgca
    58621 gaaaaatgga attagctgca aaaaaagcac ggatcggaaa acagaaggcg gtttaacaga
    58681 ggaaaggctt atggcgactg taaaacgatg cagccaaagt ttgcctttgg ctgcaatgaa
    58741 atcagtcttt atgccggtta tcaggcagga atatggtcaa catccccaat agtggcagga
    58801 aagcacagat tttatagact aactcgatac tggtgtgatc ggcgataagc cccagaactg
    58861 ccgctcccag acctcccata ccaaaagcaa aaccgaaaaa gagtccagaa accataccga
    58921 tacgtcccgg aagcagctcc tgagcgtaaa ccagaatggc agagaatgcc gaagcgagga
    58981 taaatccaat aatcaccgtt aaaacccccg tccagtgcag gctggcgtag ggtaaaatca
    59041 gcgtaaacgg cgcaacgccg aggatagagc cccaaatcac atatttccgc ccaattttat
    59101 cccctacagg cccgccgatc accgtacctg ccgcaacggc aaacaggaag gcaaacagat
    59161 gaagctgagc attctggata gataatccga atttttgcat cagataaaag gtgtaatagc
    59221 tgctgatgct cgccatatag aaatatttcg agaaaatgag gattaacaga atgctgaccg
    59281 ccagtaccac tttgttgcgc ggcagtggat tgataatcgt cgctttgggt tttcctttat
    59341 tcattcggtg ctgtgccgag taccaacggc tgatttgcgc caacaccacg atcgccagca
    59401 gtgccgcaag cacaaaccag gcaacgttgc ctttgccata aggcgcgata atcaccgccg
    59461 ccagcaaggg tcccagggaa ctgccaaagt tgccgccgac ctgaaagata gattgcgcca
    59521 ggccatgccg cccgccggaa gccatacggg ctacgcgaga agattccgga tgaaagaccg
    59581 atgaaccggt accgaccagc gccgccgcca gcagaactgc gccaaaactg cccgccagcg
    59641 caagcagcac cagaccactt aaggtaaagc acatgccaat tggcaacgac cacggcatcg
    59701 gatatttatc ggtccagtag ccgaccactg gttgcagtag cgaagaggcg agctggaagg
    59761 tgagggttat catgccaatc tgcataaatg tcagagaaaa ttctgactga agcagcggat
    59821 aaatcgccag aatcagcgat tggatcatgt cgttcagcag atgtgagagg ctgatagcac
    59881 ctaaaatacc aaacgatgtt cgggccttgg tcgttgacgc agccgcgccc gccacaggct
    59941 ggggttgttc actcattgcc ataggaaagt cactttttca gggttgcgat gtaaagaatg
    60001 atcttatttg tgattattac ccgactaaca tacctgtatg cgtcgcctga aggaagtctc
    60061 aacgccgaat acagaatttc taatctggat gcagatttat cttcaccgga cgcagacttg
    60121 tctatgatgt cgcgtcatac tatttttcaa cacgttgaaa tcaggtcagg gagagaagta
    60181 tgaaattatt gcagcggggc gtggcgttag cgctgttaac cacatttaca ctggcgagtg
    60241 aaactgctct ggcgtatgag caggataaaa cctacaaaat tacagttctg cataccaatg
    60301 atcatcatgg gcatttttgg cgcaatgaat atggcgaata tggtctggcg gcgcaaaaaa
    60361 cgctggtgga tggtatccgc aaagaggttg cggctgaagg cggtagcgtg ctgctacttt
    60421 ccggtggcga cattaacact ggcgtgcccg agtctgactt acaggatgcc gaacctgatt
    60481 ttcgcggtat gaatctggtg ggctatgacg cgatggcgat cggtaatcat gaatttgata
    60541 atccgctcac cgtattacgc cagcaggaaa agtgggccaa gttcccgttg ctttccgcga
    60601 atatctacca gaaaagtact ggcgagcgcc tgtttaaacc gtgggcgctg tttaagcgtc
    60661 aggatctgaa aattgccgtc attgggctga caaccgatga cacagcaaaa attggtaacc
    60721 cggaatactt cactgatgtc gaatttcgta agcccgccga tgaagcgaag ctggtgattc
    60781 aggagctgca acagacagaa aagccagaca ttattatcgc ggcgacccat atggggcatt
    60841 acgataatgg tgagcacggc tctaacgcac cgggcgatgt ggagatggca cgcgcgctgc
    60901 ctgccggatc gctggcgatg atcgtcggtg gtcactcgca agatccggtc tgcatggcgg
    60961 cagaaaacaa aaaacaggtc gattacgtgc cgggtacgcc atgcaagcca gatcaacaaa
    61021 acggcatctg gattgtgcag gcgcatgagt ggggcaaata cgtgggacgg gctgattttg
    61081 agtttcgtaa tggcgaaatg aaaatggtta actaccagct gattccggtg aacctgaaga
    61141 agaaagtgac ctgggaagac gggaaaagcg agcgcgtgct ttacactcct gaaatcgctg
    61201 aaaaccagca aatgatctcg ctgttatcac cgttccagaa caaaggcaaa gcgcagctgg
    61261 aagtgaaaat aggcgaaacc aatggtcgtc tggaaggcga tcgtgacaaa gtgcgttttg
    61321 tacagaccaa tatggggcgg ttgattctgg cagcccaaat ggatcgcact ggtgccgact
    61381 ttgcggtgat gagcggaggc ggaattcgtg attctatcga agcaggcgat atcagctata
    61441 aaaacgtgct gaaagtgcag ccattcggca atgtggtggt gtatgccgac atgaccggta
    61501 aagaggtgat tgattacctg accgccgtcg cgcagatgaa gccagattca ggtgcctacc
    61561 cgcaatttgc caacgttagc tttgtggcga aagacggcaa actgaacgac cttaaaatca
    61621 aaggcgaacc ggtcgatccg gcgaaaactt accgtatggc gacattaaac ttcaatgcca
    61681 ccggcggtga tggatatccg cgccttgata acaaaccggg ctatgtgaat accggcttta
    61741 ttgatgccga agtgctgaaa gcgtatatcc agaaaagctc gccgctggat gtgagtgttt
    61801 atgaaccgaa aggtgaggtg agctggcagt aatccgaaag tgccggatgt ttgcatccgg
    61861 cacaatgctt aatcgcggcg ggcgatatca gcaaatttgg catcgaggat ctttgccaga
    61921 tcgcctgccg ccagttcgat atccagtccg cgcttgccgc cggaaacata aatagtggca
    61981 aattcttgtg cgggggcgtc gataatcgtt ggcagacgtt ttttctgccc cagtgggcta
    62041 atccccccaa ccaggtatcc cgtcgaacgc tgcgcgacca tcggatcggc catctcaact
    62101 ttcttggcac ccagcgcttt tgctactttt ttaagatcca gttgacctgc gaccggcgta
    62161 acggccacgg caaggtgttt catatcaccg ttcactgcca ccagcagcgt tttgtagacc
    62221 tgatccggat tcaaacctaa ttttttgacg acttcatcgc caaaattggt ttcagccgga
    62281 tcgtgctcgt aggtatggat ttgaaacgaa atcttgtttt tttcgagtaa tttaactgcg
    62341 ggtgtcatgg taattttcct gccttaaaca aaaaaacgaa gcaagcatac gcctgatggc
    62401 ggtccaaaaa aaagagtcat cttgcctaag agtattggca ggatggtgag attgagcgac
    62461 aatcgagtta caccgtcgct taaagtgacg gcataataat aaaaaaatga aattcctctt
    62521 tgacgggcca atagcgatat tggccatttt tttagcgcaa catttgcggc aaattccctt
    62581 ctccatacag gtgtagtgca ccgaccgcga ccacatatcg ccccggcggc atggcgcgta
    62641 atttatcccg ccaggcgaga tttcgctgat gcatcagcac atcgtacagc gactgactga
    62701 acgtattggg cagcgttata tcattatttt gcggaggtgc attcagccac cagctcatca
    62761 tttgttgcag caaccgtgcg ttggtatgcc agtgggtcag cgtatcgtcc agcagcgcca
    62821 gtcctttgtc agggagctgg agcaacatgg taatctggtt ttcagcccct tccagttcaa
    62881 tcacgggttt atgttgttgc ttcgccgcct gcaataactg gtaatcgata ccgtattctg
    62941 cccgcagccc cagtttttgt gcctgcgtcg cctgaagaac catcgcgatt tgccacagcg
    63001 gttgagtaga aaagagcgac ggagaaatgc ccatttcctg gctaatgtgc tgcagatttt
    63061 ggagttgctc ctcgttaatg cgctcttcca gcgcctcgca agtaggcaaa ttagcaaaag
    63121 gcgtatcgct ggtggaaaca tccgcctcga cgatcagcgc atcggcgttt ttgagctttt
    63181 tgagcaaacg ggtgggcagg ggagccatat cgtggctacc catatgaata ctgccaatca
    63241 gatgaaaatg gcgattgccg ggaagggtga tatcgatggc aggccaggtg taatgattac
    63301 cgcgcagcgc ggcccaaagc gtttttaccc ggtacaacag atccatacga cctccctttg
    63361 tgaaatatca tgctagcgcg cggtgaggga tggcgcaaat ggagttgggg acttgtttaa
    63421 tgtgtttgta tgattcagta tgttcttgca tcgctattca cagggaagca acagttaaaa
    63481 accatgaaac aggcaacaag aaaaccgacg acacccggag atattcttct ctatgaatat
    63541 ctggaaccgc tcgatttgaa aatcaatgag ttagcagagt tgctgcatgt tcatcgtaat
    63601 agcgtcagtg cactgatcaa taacaatcgt aaactcacca ctgagatggc attccgtctg
    63661 gcgaaagttt ttgataccac agtcgatttt aggctaaacc tccaggcggc agttgatctt
    63721 tgggaagttg aaaacaacat gcgcacccag gaagaattgg gacggattga aacagtggct
    63781 gaatatttgg cacgccgtga agagcgtgca aaaaaggtcg cgtaaggcca aaacatcgct
    63841 tcatctcgta ggccggataa ggcgtttacg ccgcatccgg cagtcatgcg tcgatgccaa
    63901 atgcgccgcc ctaaagcagc gcatccgcaa tgacgtactt attccttcgg tttaaaccgc
    63961 agcaaccggt tggcgttact cactacggta atcgacgaga gcgccattgc cgctccggca
    64021 actaccgggt taagcagtgt tccagtaaac ggccacaaaa taccggcggc gaccggaata
    64081 ccgatgctgt tgtagataaa ggcaccgagc aggttctgct tcatgttgcg cagcgttgcg
    64141 cgggaaatcg cgagcgcatc cgcaacgccc atcaggctat ggcgcatcag ggtaatcgcc
    64201 gcggtttcaa tggcaacatc actgccgcca cccatcgcaa tgccgacatc cgcctgggcc
    64261 agcgctggcg cgtcgttaat gccgtcgccc accattgcca cctgacgtcc ttcactttgc
    64321 agacgtttga tcgcttcggc tttaccgtcc ggcagcactc cggcaatcac ttcatcaatt
    64381 ccagcttctt tggcgatcgc attggcggtg gttgggttat ccccggtcaa catcaccaga
    64441 cgatatcccg ctttatgcag gcgttgcagc gccgccacgc tatcactacg caacggatcg
    64501 cgtacagcca gcagggctac tgctttcccg tcaatcgcca gcagcacagg cgttgctcct
    64561 tgcgatgcct gagcagtaat ctccgcttcg atagctttgg taccaacctg ttgctcattt
    64621 aacagcgcct gattgcccag caataacgca tgaccttcag cttcaccgct cacgcccagc
    64681 ccgcgcaatg tgcggaaacc gttgacctgc ggcagctgca tatcacctgc tttatcgagg
    64741 atcgcccgtg ccagcggatg gctggaacct tgctccagtg ccgccgccag acgcaatgcc
    64801 tgcgcttcat caacatcagc aaacgttttc actgcgacaa cctgcggctt cccttcggtc
    64861 agcgtcccgg ttttatcgaa cacgacggta tcgagtgtac tggcgcgttg cagcgcgtcg
    64921 gcgtcccgca ccagcacgcc aaactcagcc gcccgcccga cgccggaaat aatcgacatc
    64981 ggcgtcgcca gccccagcgc acacggacag gcgataatca gtaccgtggt ggcaatcacc
    65041 agggtataaa caatttgcgg tgccggacca aagaagtacc agattgccgc actgaccagc
    65101 gcaatcacca ccaccacagg tacaaatacg gctgagattt tatccgccag ctgaccgatt
    65161 tctggcttgc tgctctgggc ctggcgcacc atgcgaatga tccgtgacag cgtggtatgg
    65221 ctgccaaccg cactggcacg aaacagcacg ctaccgtcct gtaccactgt cccggcatgg
    65281 acgctttcgc cttcgccttt ttgctgcggg attggttcgc ccgtcagcat cgcttcatcc
    65341 agccatgctt cgccctgggt aatctcgcca tctaccggca cgcgatcgcc ggtcgtcagg
    65401 cgcagcaaca tacctggctg cacttccgcc agaggcacgc ttttttcacc ttcgtcagta
    65461 accaggcgcg ccgtcggtgg ggttaaatcg agtaatttct ccagcgcctt agaagaacgc
    65521 tgacgtgcgc gtgcttccag catatggccg agattgatca gaccgataat catcgcgctg
    65581 gcttcgtaat aaagatgtcg cgcttccatc gggaaccact gcggccacag gttgacgctc
    65641 atcgaataga gccacgccac gccagtaccc agcgccacca gcgtatccat cgtcgctgca
    65701 ccgttcagca ggcttttcca tgcactgcgg taaaaatggc cgccggcgaa aaccatcacc
    65761 gccagggtta tcaggccgat aaccaaccac aggctgcggt tgtcagcggt gaccatcatg
    65821 ttatcgccaa tcatccccca gaccatcacc gggataccca ccgccagtgc gacaattgcc
    65881 tgccagcgga agcgcttcat cgtagcaacg gcggtttcct gctggcgctc acggcgtttc
    65941 gcgtcatctt caatcgcttc cgcgccgtag cccgcttttt ccaccgcctg cactaaatct
    66001 tgtggggagg cactgcccat caccagcgca gtacgctccg ccaggtttac ccgtgcctga
    66061 gtgacgcccg gtacgctttg cagcgcattt tgtacgcggg tgacacagct ggcgcagctc
    66121 atgccgctca gcagcaactg ctggctgtca tcgtcatcgg cggtcgctgc cggaagcgcc
    66181 tcagaaaccg ctgtcagtgc ttccgacggg attgatgact ccgccagcgg tttagccttt
    66241 gggtggctta cagatgcgtc ataacccgct tgtttgatgg tttcgatcag ctgttctgca
    66301 ctggcagtcc cggtaacgtg cgcttcagtg atagacacat ccgcttgttc cacatccggg
    66361 cgctgttcga gactttcttt cacgcgttta acgcagtgac cgcaggacag gccgtccagg
    66421 gtcaggtcga taatttgtga cataaaacac tcctttaaga cagttttgac tggctgtgat
    66481 aaaggttaaa ccttccagca aggggaaggt caagaaatta ataaaccagg cgagtaaaag
    66541 tccgtaaaga ttaaaaaatt ggctcaattt gcatcaggat tagacattta tctctttgtt
    66601 ttcctgtagt taagttgcgg gtgctaagtt aaatcaggat gcctcaaaat cggcaccggg
    66661 gtgaggaatt acctcccgca tctataaaaa ggagttaaca aaagatgtta gatgcaaaca
    66721 aattacagca ggcagtggat caggcttaca cccaatttca ctcacttaac ggcggtcaaa
    66781 atgccgacta cattcccttt ctggcgaatg tgcctggtca actggcggca gtggctatcg
    66841 tgacctgcga tggcaaggtc tatagtgcgg gtgacagtga ttaccgcttt gcgctggaat
    66901 ccatctcgaa agtctgtacg ttagcccttg cgttagagga tgtcggcccg caggcggtac
    66961 aggacaaaat tggcgctgac ccgaccggat tgccctttaa ctcagttatc gccttagagt
    67021 tgcatggcgg caaaccgctt tcgccactgg taaatgctgg cgccattgcc accaccagcc
    67081 tgattaacgc tgaaaatgtt gaacaacgct ggcagcgaat tttacatatc caacagcaac
    67141 tggctggtga gcaggtagcg ctctctgacg aagtcaacca gtcggaacaa acaaccaact
    67201 tccataaccg ggccattgcc tggctgctgt actccgccgg atatctctat tgtgatgcaa
    67261 tggaagcctg tgacgtgtac acccgtcagt gctccacgct cctcaatact gttgaactgg
    67321 caacacttgg cgcgacgctg gcggcggggg gagtgaatcc gctgacgcat aaacgcgttc
    67381 ttcaggccga taacgtgccg tacattctgg ccgaaatgat gatggaaggg ctgtatggtc
    67441 gctccggtga gtgggcatat cgcgttggtt taccgggcaa aagcggtgta ggtggcggta
    67501 ttctggcggt cgtccctggt gtgatgggaa ttgccgcgtt ctcaccaccg ctggacgaag
    67561 aaggcaacag tgttcgcggt caaaaaatgg tggcatcggt cgctaagcaa ctcggctata
    67621 acgtgtttaa gggctgatca tgatgaacac ggaaggtaat aacggtaaca aacccctcgg
    67681 tctatggaat gtcgtttcca tcggtattgg ggcaatggtg ggggcgggga tcttcgcgct
    67741 gctggggcag gctgcgttgc taatggaagc ctcgacctgg gtcgcctttg cttttggcgg
    67801 tattgtggcg atgttttccg gttatgccta tgcgcgtctg ggggcgagct atcccagcaa
    67861 tggcggcatt atcgacttct ttcgtcgcgg attaggcaac ggcgtctttt cgctggcgct
    67921 ctcgttactg tacctgttga cgctggcggt gagcatcgcc atggtcgccc gtgcttttgg
    67981 cgcttatgcc gtgcagtttt tgcatgaagg cagccaggag gagcacctta ttttgctcta
    68041 cgcgttgggg atcattgcgg tgatgacgct tttcaactcc ttaagcaacc atgcggtagg
    68101 gcggctggaa gtgatcctcg tcggcattaa aatgatgatc ctgttattgc tgattattgc
    68161 cggtgtctgg tcgctgcaac cggcgcatat ttccgtctct gcgcccccca gctccggtgc
    68221 gttcttctcc tgtatcggga taaccttcct tgcctatgcg ggctttggca tgatggcgaa
    68281 cgcggcggat aaagtgaaag atccgcaggt cattatgccg cgggcgtttc tggtggcgat
    68341 tggcgttacc acgttgcttt atatctcgct ggcactggtt ttgcttagcg atgtatcggc
    68401 attagagtta gaaaaatatg ccgataccgc cgtagcgcag gctgcttctc cgctgctcgg
    68461 acatgtgggt tatgtgatcg tcgtcatcgg cgctttactg gcgacggctt cagccattaa
    68521 cgcgaacctg ttcgccgtgt ttaacatcat ggacaacatg ggcagcgaac gcgaactgcc
    68581 gaagctaatg aataaatccc tgtggcggca gagtacctgg ggcaacatca ttgtcgtggt
    68641 gttgattatg ctgatgacgg cggcgctaaa tttaggctca ctcgccagtg ttgccagcgc
    68701 cacctttttg atttgctacc tggcggtgtt tgtggtggcg atccgcctgc gtcatgatat
    68761 tcacgcctcg ttgccgattc ttatcgttgg tacgttggtg atgttgttgg tgatcgttgg
    68821 ctttatctac agtctgtggt cccagggtag ccgtgcgttg atatggatta ttggctcact
    68881 cttactcagc cttattgtgg caatggtcat gaagcgcaat aaaaccgtat aacatctctc
    68941 tgtgcgcagt acttcctgta ttattgtggt ggcggtcgat attcgcactg gcaaaaaaac
    69001 gtgcttgaat atctgttgaa accctttaac aaagcacagg aggcgttgcg cgaacgatga
    69061 acatcagcga tgtagcaaaa attaccggcc tgaccagcaa agccattcgc ttctatgaag
    69121 agaaggggct ggtgacgccg ccgatgcgca gcgaaaacgg ttatcgcacc tacacgcagc
    69181 agcatctcaa cgaactgacc ttactgcgcc aggcacggca ggtgggcttt aacctggaag
    69241 agagcggcga gctggtgaat ctgtttaacg acccgcagcg gcacagcgcc gacgtcaaac
    69301 ggcgcacgct ggagaaggtg gcggagatcg aacgacacat tgaggagctg caatccatgc
    69361 gcgaccagct gctggcactg gcgaatgcct gccctggcga tgacagcgcc gactgcccga
    69421 ttatcgaaaa tctctccggc tgctgtcatc atcgggcagg gtgattaaga cgagacggct
    69481 cggatatgta gggttatccc ttctatcgca atgacttcaa catgcgtacc tgcaccgaga
    69541 tcctcgctgg cgctgacagg ccatgaactg tcaccgacgc gcatatgacc gcgcccgttg
    69601 accagcggag attccagcac aaaacgtcgg ccaatcagct gctgcccgcg ctggtttaaa
    69661 tgactatcgc tgtgcttttg ttcgcgcacc cgccgcgaca accatttcca ccacagccag
    69721 gcggcgagca gcgtcaggat ggcaaacatt accccttgcc actcccaacc cagcggcacc
    69781 agccagacca ccaggccggt aatcaccgct gccacgccgc tccacaacaa ataaccattt
    69841 ccgcccagca tctcggctgc cagcagcaaa ccgccgagac tgagccagaa aatatgtgga
    69901 tgaacgacca ttaactccat catggctgag tccgtttgtt ggcgctgtct ttcaccagct
    69961 cggcaatccc ggcaatcgac cccatcaggc tgctggcctc taatggcatc atcactactt
    70021 tgctgttact ggaggaaccg atctgctgta acgcttcggt gtatttctgc gctacgaagt
    70081 agttcaccgc ctgaatatca ccggaggcga tggcttcaga caccattttg gtggcgcggg
    70141 cttctgcttc agcggaacgt tcacgcgctt cagcctgtaa aaacgccgac tgacgttcgc
    70201 cttccgcttt caggatttgc gactgttttt caccttcggc tttgaggatt tccgcctgac
    70261 ggatcccttc cgcttcaaga atgtaagcgc gtttggtacg ttccgctttc atctgcgcgt
    70321 tcattgaaga gataagctct gccggtgggc gcacgtcgcg aatttcaata cgggtgactt
    70381 taatccccca cgggttggtg gcttcatcga caatacgcag caggcgtgag ttgatgctgt
    70441 cgcgctgaga gagcatttcg tcaagttcca ttgaacccaa cacggtacgg atgttagtca
    70501 tggtcaggtt gatgatcgcc agctccagat tgctgacttc ataagccgcg cgcggcgcgt
    70561 caatcacctg aataaaacag actgcgtcga tggtaacgtt ggcgttatct ttcgagataa
    70621 cttcctggga agggatatcg agcacttgct ccatcatatt gatcttgcga ccaatgcgat
    70681 ccataaacgg caccaccaga ctgagccccg gctgtaacgt tttggtatag cgaccaaaac
    70741 gttctaccgt ccattgatag ccctgcggca cgattttgac gcccgcgccg acaatgacca
    70801 gcgcgacaaa aatgagaatc gggataaaga taagcatcgg aaaaacctcc tgttgtaccg
    70861 tccataatca gcaaaattgc tgcttgatta aacaaattat acctgattac tgaaagagag
    70921 ttccccctta ttcctgcgaa ggataaactg tttttagtaa aaatcagaaa aagggaacag
    70981 tgatgcagga aaatagtcct ttgcttcagc tacaaaacgt aggatatctg gcgggtgatg
    71041 cgaagattct taataacatc aatttttcgc tgcgtgctgg cgaatttaag ttaattaccg
    71101 gtccttccgg ttgtggcaaa agtacgctgc taaaaatagt tgcttcattg atcagcccaa
    71161 ccagcggaac gttactgttt gaaggtgagg atgtcagcac actaaagcca gaaatctacc
    71221 gccagcaagt ctcttactgc gcccagacgc cgacgctgtt tggcgatacg gtatacgata
    71281 atctgatctt tccctggcag atccgtaacc agcagcctga cccggccatt tttctcgatt
    71341 ttctcgaacg cttcgctttg ccggacagca ttttgacgaa aaatatcgcc gagctatctg
    71401 gtggtgaaaa acaacgcatc tcactgattc gtaacctgca atttatgccg aaggttttat
    71461 tgctggatga aatcaccagt gcgctggatg aaagtaataa acataacgtt aatgagatga
    71521 tccatcgtta tgtgcgcgag caaaatattg ccgtgctgtg ggtgacacac gataaagacg
    71581 aaattaatca tgcggataaa gtgattacac tgcaaccgca tgccggagaa atgcaggaag
    71641 cacgctatga actcgcataa tattactaac gaatcattgg cactggcatt aatgctggtg
    71701 gtggtggcaa tcttaattag ccataaagaa aaactggcgc tggagaaaga tattttctgg
    71761 agcgtcgggc gagcgataat tcagctgatt attgtcggct atgtgctgaa gtatattttc
    71821 agcgtggatg atgccagcct gacattattg atggtgttat ttatctgctt taatgcggcg
    71881 tggaacgcgc aaaaacgcag taaatatatt gctaaagctt ttatctcatc gtttattgcc
    71941 attacggtcg gggcgggaat taccctggcg gtgctgattc tctctgggtc gattgaattt
    72001 atcccgatgc aggtgatccc tatcgccggg atgattgccg gtaacgccat ggtagcggtg
    72061 gggttgtgtt acaacaattt agggcaacgg gtcattagcg aacagcaaca gattcaggag
    72121 aaactgagtc ttggtgcgac gccgaagcag gcttcagcga tattgattcg cgacagtatt
    72181 cgcgcggctt taattccgac ggtcgattca gcaaaaacgg ttggcttagt gagtttacca
    72241 ggaatgatgt ccgggctgat atttgccggg attgatccgg tgaaggcgat taaatatcag
    72301 attatggtga cctttatgct gctctcaacc gccagcttgt cgaccattat tgcctgctat
    72361 ttaacctatc gtaagtttta taattcgcgc caccagttgg tggtgacgca attgaagaag
    72421 aaatgatgcg atgccggatg cgcagcatcg catccggcgt tgtggttcat gtgccgatca
    72481 acggaatatc aatacaacaa tgcatacagc tggcggcgat acttcgacgc cagtgcatca
    72541 cccgtaccca gcgcagcgag gatctcctgg aacgttttac gcgtctgacc gtctgcggcg
    72601 gtgagatctt tacgcagatg cccgaacagc aactccagcg cctcttcatt gcgcccaacc
    72661 tggtgcagtt gcagagccag ttgcgtcgcc agtgcggcat cttctggatt ctccgccacc
    72721 tgctgttgca actgttgaat ttccggcgta tcagccgcct gcttcagcag ttcgatttgc
    72781 gccaccagcc cctggtagcg ggtgtcctga tcctgcaacg gaatggtttt cagcaccgct
    72841 tccgcatctt cagaacggtt cagcgcaatc agcgtttctg ccagcagcag gccgatctcc
    72901 ccgttctgat tcgacaactg ccaggcgtct ttcagcaatg gcagggcatc ggtgtaattg
    72961 ccttcctgca tcagttgcat cgcctgctgc gctttcagct cttcttcgcg cggcagcact
    73021 ttatccagca gggcgcggat cgcctcttcc ggttgcggcc cctggaagcc atctaccggt
    73081 tgcccgttct ggaacagata cacggtcgga atcgcgcgca gaccaaactg ggcggcaatc
    73141 atctgctccg cgtcgcagtc cagcttcgcc agaataaatt gcccgttgta ctgcgccgca
    73201 aggctttcca gaattggggt taactgcaaa cagtgctggc tacgttcaga ccaaaaatag
    73261 aacagcaccg gagtggtcat cgactgttca agaacctgtt gcaggttaga ttcgttaatg
    73321 ttgacaatat tttctacgga catggagtcg ctctctgttg tcgatatttt ctttgacatg
    73381 ggggcttaag cgcgcgcttc aactcacccc tgcaatattt tgtccatcac gcgccccggc
    73441 agcaggcgct taagcaccat tactgcccag gtcaccagcg ttaccggata gcgcatcttc
    73501 ggcttctcgc taataaaagc atggcgcact ttgtccacca ccgcttccgg tcccaacgta
    73561 aagcgggcgg cgatgccggg attttcgact ggtttatcac tttgcgtctg gttgacgttg
    73621 tcggtgaagc gggtacgaat aggaccgggt tcgatcaggc taactttaat tccgctgtgg
    73681 cgcagctcca tgcgcagtgc gtctgaccac gcctccagcg catatttact ggccgcgtaa
    73741 gcgccgcgac ccggcgtgga gattaatccc atcaccgatg atgtcatcac aatacgccct
    73801 tcaccgtgcg gtaacatcgc gggtaacagg cgtatggtga gctggtgtgc gccgaaaaag
    73861 ttggcggaaa actgctgttc catctgcgcg cggctgatgg tggaaagggg gccatacatg
    73921 ccgaatccgg cattgttaaa gatcccatac agacaattat cggtcagggc gatcacttcg
    73981 tcggctgcgc gatcaacact ttctggcgaa tccagatcga tcaacacgcc ggtaaatccc
    74041 atgctgttca tgcgctcaac atcatccggt ttccggcaac ctgccagcac atgaaaaccc
    74101 tggcgtttta attcgagcgc gctttccagg ccaattccac tggaacatcc ggtaattaag
    74161 accgattttt gcataacttt acctgtcagg atctccgttg ctttatgagt catgatttac
    74221 taaaggctgc aactgcttcg ccatccagtc ggcaataaac ggctgggcgt cgcggttggg
    74281 atgaataccg tcatcctgca tccattgtgg cttgaggtag acctcttcca taaaaaaggg
    74341 cagcagcgga acatcaaact ctttggcgag tttggggtaa atggcgctaa aggcttcatt
    74401 ataacggcga ccatagtttg caggcagacg tatttgcatt aacaatggtt cagcgttggc
    74461 ggctttgaca tcctgcaaaa tctggcgcag cgtttgctcg gtttgctgtg gctgaaaacc
    74521 acgcaaaccg tcattgccgc ccagttcaac cagcacccaa cgcggctgat gctgtttcag
    74581 cagagccgga aggcgcgcca gtccttgttg cgaggtgtcg ccgctgatgc tggcattaac
    74641 taccgacgtt ttactctgcc acttatcatt caacaaggca ggccaggccg cgctggcaga
    74701 cattcgatac ccggcgctca ggctatcacc cagaatcaat aacgtgtccg ctgcggcggc
    74761 acggaaggtt aacaggacca ggaacaggaa gggcaaatgc cagcggaaaa cattgttgaa
    74821 gttcatcatc ttaagaagtc cgtcggtcag ggggagcatg aactctccat cctcaccgga
    74881 gttgagctgg ttgtcaaacg tggcgagacc attgcactgg tgggcgagtc gggatcgggt
    74941 aagtcaacct tgctggcgat cctcgccggg ctggatgacg gcagcagtgg cgaagtgagt
    75001 ctggtgggac aaccgctaca taatatggac gaagaagcgc gggcaaagtt gcgcgcgaag
    75061 cacgtaggct ttgtttttca gtcatttatg ttaattccta cccttaacgc cctggaaaac
    75121 gtcgagcttc cggcgctgct gcgcggtgag agtagcgcgg aaagtcgtaa cggggcgaaa
    75181 gcgttgctcg aacagttagg gctgggtaaa cgtcttgatc atcttccgac acagctttcc
    75241 ggcggcgaac agcaacgagt ggcgctggcg cgagccttta atggtcgacc tgatgtgctg
    75301 tttgccgacg aacccaccgg caaccttgac cgccagacgg gcgataaaat tgccgacttg
    75361 ctgttttccc tcaaccgtga gcatggcacc acgttgatta tggtgaccca cgacctgcaa
    75421 ctggcggcac gctgcgaccg ctgcttacgg ctggtgaacg ggcagttgca ggaggaagca
    75481 tgattgcacg ttggttctgg cgcgaatggc gctcgccgtc gctattaatt gtctggctgg
    75541 cgctaagcct ggcggtggcc tgcgtgctgg cgctgggcaa tatcagcgat cgcatggaga
    75601 agggcttaag ccagcaaagc cgggagttta tggcgggcga tcgggcgttg cgcagttcgc
    75661 gcgaagtgcc gcaagcgtgg ctggaggaag cgcaaaagcg cggcctgaaa gtcggcaagc
    75721 agctgacttt cgccaccatg acatttgcag gcgacacacc gcagctggcg aacgtcaaag
    75781 cggtggatga tatctatccg atgtatggcg atctgcaaac caatccccct ggcctgaaac
    75841 cgcaggcggg cagcgtattg ctggccccac gcctgatggc actacttaac ctgaaaacgg
    75901 gcgacaccat tgacgtgggc gatgccacct tgcggattgc cggagaagtg attcaggaac
    75961 cggattccgg ttttaacccc ttccagatgg ctccgcgtct gatgatgaat ctggcggatg
    76021 tcgataaaac cggagccgtg cagccgggga gtcgggtcac ctggcgttat aaattcggcg
    76081 gcaacgagaa ccagctcgac ggctatgaga aatggttgtt accccagctt aaacccgaac
    76141 aacgctggta cggtctggaa caggacgaag gcgcgctggg gcgatcgatg gaacgctcgc
    76201 aacagttcct gctgctttcg gcgcttctga ccttgctgct ggcagtggca gcggtggcgg
    76261 tagcgatgaa tcattactgt cgcagtcgct acgatctggt ggcgatcctc aaaacgctgg
    76321 gggcagggcg agcgcaactg cgtaagctaa tcgtcggtca gtggttgatg gtgctgacgc
    76381 tttcagccgt taccggtggg accataggcc tgttgttcga aaacgtgttg atggtgctgc
    76441 tcaagcccgt tctgcctgct gcactaccgc cagccagcct ctggccgtgg ctgtgggcgc
    76501 ttggcaccat gacggtcatc tcgctgctgg tggggctacg accataccgc ttgttgctgg
    76561 caacgcagcc tttacgcgta ttacgtaatg atgtggtagc gaacgtctgg ccgctgaagt
    76621 tttatctgcc gattgtcagt gtggtggttg tgctgctgct cgccggatta atgggtggca
    76681 gcatgctgct ttgggcggtg ctggcgggcg cggtagtact ggctttgctg tgcggtgtgc
    76741 tgggctggat gcagctgaat gtacttcgcc gcatgacgct gaaatcgcta cctctgcgcc
    76801 tggcggttag ccgcctgtta cgtcagccgt ggtcaacgtt aagccagctt tcggcatttt
    76861 cgctctcctt tatgctgctg gcgctgttgc tggtattgcg tggcgatctg ctcgaccgct
    76921 ggcagcagca gctaccgcca gaaagcccga actacttttt aattaacatc gccacagaac
    76981 aggtagcacc gctaaaagcg ttcctcgcgg aacatcatat agtcccggaa tcattttatc
    77041 cggtagtgcg ggcgcggctg acggcgatta acgataagcc gacagaaggt aatgaagatg
    77101 aggcgcttaa tcgcgaactc aatcttacct ggcaaaatac gcggcccgat cataatccga
    77161 ttgtcgccgg taactggccg ccaaaagccg atgaagtgtc gatggaagag gggctggcga
    77221 aacgcttaaa cgttgccctc ggtgataccg tgacttttat gggcgatacc caggagttcc
    77281 gcgctaaagt gaccagcctg cgcaaagtgg actgggaaag tctgcggcct aatttctatt
    77341 ttattttccc tgaaggggca ttagacgggc aaccgcagag ctggcttacc agtttccgct
    77401 gggagaatgg caacggcatg ttgacacaac tcaaccgcca gttcccgacc attagcctgt
    77461 tagatattgg cgcgatttta aaacaggtcg gtcaggtgct ggagcaggta agtcgggcgc
    77521 tggaggtgat ggtggtgctg gtcaccgcct gcggtatgtt gctgttgctg gcacaggtgc
    77581 aggtgggaat gcgccagcgt catcaggagc tggtggtatg gcgcacactc ggtgcgggga
    77641 aaaaactgct gcgcacgaca ttgtggtgtg agttcgccat gcttgggttt gtttccggcc
    77701 tggtggccgc aattggtgcg gaaacggcac tggcagtgtt gcaggcgaaa gtgtttgatt
    77761 tcccgtggga gccagactgg cgattgtgga ttgtgctgcc gtgcagcggt gcgctgctgc
    77821 tgtcgctttt cggcggctgg ctgggcgcga gactggttaa gggtaaggcg ctgttcaggc
    77881 agtttgcggg gtgatgacag gcgttagatt gcctgatgcg ctacgcttat ctggtctacg
    77941 aagatcgtgc aatatattga ttttgcaaga ttgtgtaggc cggataaggc gtttacgccg
    78001 catccggcat gaacagtgtg cattttggca ataaatatga aaccaactgt catgtcggtt
    78061 tttttaaagg ccgaaggtgg taaaccttcg gccttagcta cgtttcctca gttattcaat
    78121 aaactgacgg atcagttcca gcagcgcgat tagcgcctta agaacgatga gaactttatc
    78181 gagaaaagtt ttcatccgtt gctcccttaa gggagaaaga caatcacagc ttacccttac
    78241 gttgcctgta actatgattt tcttcatgtg ctagatgagg actgcctctc tccaaattag
    78301 agcaccagaa tcagcaccac ctgtatcctg accaggactt aaaagtactt ttccgcactg
    78361 cggtaatccc ttgaggcagt atcactacta gcgtcgggat tgtatcgcca acatagctgt
    78421 ttgaatatgt aggcatcctg acttataatt cgcttgctag atgaggactg tttcatttct
    78481 gcccggaacc accaagtctt gggcggaaaa aataaaaaaa ccgactgtca tgtcggtttt
    78541 tttatatctg tattctggtg caaccattct gttctcacga caatcgccgt ttcagaatac
    78601 cgcccatcac tgcgccttaa cccattccgc cacttccgcc cactcaccgc gaaagacaac
    78661 tttttccgct tttttctcaa gctgatagcg atacattggg tcgtaatatt ctttaagtaa
    78721 cggcaccagc caggccagat gaccgtcggt gctgccggtg gtgagttgcg ttgtcagcgc
    78781 cgtatccagc tgggcagcga gttcgttata gcgctgtaac cccagccgac gcttaatcgc
    78841 cgaaagtccg tgatgcaggt attcgcaata ttcctgccag ccctgttcgt cgccataagc
    78901 gtgggtaaaa tcatgatgca tacgcaagaa atactcttcg ttcaggcgtt caagacggat
    78961 ctcaaacgga tcttctacca ccgcaatcgc cgcctgagtc attcgctcgc gcagacattc
    79021 cggcaggtga ttcgaaccga tcatccggct ttcgtcttcc agcacccaca ggcgcaaatc
    79081 ctgacgggcg tcggttttca gcatttcggc agccagcagg ttttcaaaac tcgcctggct
    79141 aagttgtggt tgtaacgtgc gaccaaacgc cgaaccgcga tggcgcgcca gcccttccag
    79201 atcaacaccg ttcggctgtt gctgcactaa cagcgtttta ccgctgccag tacaaccgcc
    79261 aatcagcact atcggttttt gtgccagttc aatagtcgcc tgaatcgcgg tctggcgcag
    79321 tgccttataa ccgccttcca ccagcggata atcaatcccc gctgcataca accagctttg
    79381 cacaatatgt gagcgctgac cgccacgggc gcagcagaga ataccttgcg gattttgcag
    79441 gcacgctgcc cgccaggcgt ccatgcgctg ctgacgaatt tcacccgcca ccagtttatg
    79501 ccccagcgcc agcgctgcgt ctgagccttg ctgtttatag caggtgccaa cggcggcgcg
    79561 ttcatcgtta ttcattaacg gcagattgat agcggcgggc attgcgcctt gctcaaactc
    79621 gataggggcg cgaacatcaa taatgggcgt atcagcaatc agcagggcac gatagtcctg
    79681 ttccgtgtgt ctctcttgca tagttaaaag tgaacctcaa atcagcttgc gcgctatttt
    79741 acgcgccaac gcgcaaggaa acttgatttt taactgcgtg ggttgccgaa aatttctaaa
    79801 aatccgctga tttccggcct gcgctgggta aacaaggtca caatatcttc taccgctttg
    79861 ccgctgccaa atttgcgcca tgccagactc aatggcgaag gagggcgcat cgttgggatt
    79921 acccggctaa ccagttgttg attatcgatc attgactggc aaagcgattt tggcaaaaaa
    79981 ccaatgccaa cgcccgcaag atgggcggcg attttcgttt ccatatcagg aacaataatc
    80041 tctttttgcc ctggcaatcg ccaggcgacg cgtttggtta aggtgcgggc gctgtcttca
    80101 atattgaccg ccggaaagcg ccgcaactgc gcttctgtta gcggctcttc aacgttcgcc
    80161 agcggatgat ccgccgccat gacaaagcgc cattgcaccg atcctaaggg atcaagacta
    80221 aaggtatttg ccagcgcctc ggttcccgtg acgccgatag ccagtgaaaa accttcgtac
    80281 aatagcgaat cccagacgcc catatagatt tgtcgggaga tgtgaaactg ggtaaagggg
    80341 taacgttcat tcagccacgc cagcaactgg gcgacggcct gggggttgta gagcaggttg
    80401 ttgatgacaa tattcacctg gcgttccacg ccatcattca cctgttgcag ctcgcttggc
    80461 atactttcca gccagctcag ccagtctctg gcctgggaaa gtagatgctc gccagccgct
    80521 gtcaacgtca cgctacgagt cgtacggaaa aacagcgcta ctccggtatt ctcttccaga
    80581 agtttaatgc gataactgat cgtcgccgtg gttttacata atcgttctgc cgcttttgaa
    80641 aaacttcctg tttcagcaac cgcaatgaaa gtccgcaagg tttctggatc gaacatcttc
    80701 aggtatcccc ttttaaatcc gcaagttgcg tgattttctt atcctctgat ttatcagtat
    80761 ttttacatga taaccctgtt caatttgtgg actaaatcta gttttggaaa aatattccaa
    80821 cttttgtatt gatgttgttc tcttaaggtt ttagattgcc tgttattgaa accaagctga
    80881 ccggtcggcg atggttgaac ggaattatgt tacaaggaca aaaagatgaa acttcaggta
    80941 ttaccgttaa gtcaggaagc ctttagtgct tatggcgacg taatcgaaac tcagcaacgg
    81001 gattttttcc atattaacaa tggcctggtg gagcgttacc acgatttggc gctggttgag
    81061 attcttgagc aagaccgtac gcttatcagc attaaccgcg cgcaaccggc gaatctgccg
    81121 ctgaccattc acgaactcga acgtcatccg ctgggcactc aggcctttat cccgatgaaa
    81181 ggtgaagtgt ttgtggtggt cgtggcgtta ggcgacgaca aaccagacct gtcaacgctg
    81241 cgggcgttta tcaccaacgg cgaacaggga gtgaattacc atcgtaacgt ctggcatcac
    81301 ccacttttcg cctggcagcg cgtcaccgat tttctgacca tcgatcgcgg cggcagtgac
    81361 aactgtgatg ttgaaagtat tcctgaacag gaactctgtt ttgcgtgacg cctgcaaccg
    81421 acttgcataa gataaactaa ttgttcattg tttatgctca cttgtaggtc ggagttaacg
    81481 taggtatgac ggaagttaga cggcgcggca ggccaggaca ggcggagcct gtggcacaga
    81541 agggcgcaca ggcgttagag cggggaattg cgattctgca atatctggaa aaaagtgggg
    81601 gaagttcgtc ggttagcgat atttctctca atctggattt gccgctctcc acgacctttc
    81661 gcttgctgaa ggttttacaa gcagcggatt ttgtctatca ggacagtcaa ttaggctggt
    81721 ggcatatagg attaggtgtc tttaacgtcg gtgcagcgta catccataac cgcgatgtcc
    81781 tctccgtcgc cgggccgttt atgcgccgcc tgatgttact ttccggcgaa acggtcaatg
    81841 tcgcgatccg taacggcaat gaagcagtat taattggtca gttagagtgt aaatcgatgg
    81901 tcaggatgtg tgcgccactg ggcagtcgtc tgccgctgca tgcttccggt gcgggcaaag
    81961 cgctgcttta tccgctggcg gaagaggagt tgatgagcat cattctgcaa accggtttgc
    82021 agcagtttac gccaactacg cttgtggata tgcccacctt gctgaaggac ctggaacaag
    82081 cgcgtgaact gggctatacc gtagataaag aagagcatgt tgtaggtctg aattgcatag
    82141 cttcagcaat ttacgatgat gtcggtagtg ttgttgccgc tatctccatc tccgggcctt
    82201 catcaagact gacagaagat cgttttgtca gtcagggtga gctggtcaga gacaccgccc
    82261 gcgatatcag cacggcgttg ggactgaaag cacatccata atgtctgtcg catcccgctc
    82321 tgcggagcgg gtttttttga caaaatttga aagttggaaa aattttccaa taaatagagg
    82381 taggaataaa atggcaaaaa tgagagccgt tgacgcggca atgtatgtgc tggagaaaga
    82441 aggtatcacc accgccttcg gtgttccggg agctgcaatc aatccgttct actcagcgat
    82501 gcgtaagcac ggcggtattc gtcacattct ggcgcgtcat gtggaaggtg cttcgcacat
    82561 ggcggaaggt tatacccgcg caacggcagg aaatatcggc gtatgtctgg ggacttccgg
    82621 tcctgcgggc acggacatga tcaccgcgct ctattccgct tctgctgatt ccattcctat
    82681 tctgtgcatt accggccagg caccgcgcgc ccgtctgcat aaagaagatt ttcaggccgt
    82741 agatattgaa gcaattgcta aaccggtcag caaaatggcg gttacagttc gtgaagcggc
    82801 gctggtgcct cgcgtgctgc aacaggcatt tcacctgatg cgttctggtc gtccgggtcc
    82861 ggtactggtg gatttaccgt tcgacgttca ggttgcggaa atcgagtttg atcctgacat
    82921 gtacgaaccg ctgccggtct acaaacctgc tgccagccgt atgcagatcg aaaaagctgt
    82981 agaaatgtta atccaggccg aacgtccggt gattgttgcc gggggcgggg taattaatgc
    83041 tgacgcagct gcactgttac aacagtttgc tgaactgacc agcgttccgg tgatcccaac
    83101 gctgatgggc tggggctgta tcccggacga tcatgaactg atggccggga tggttggtct
    83161 gcaaaccgcg catcgttacg gtaacgcaac gttgctggcg tccgacatgg tgtttggtat
    83221 cggtaaccgt tttgctaacc gtcataccgg ttcggtagag aaatacaccg aagggcgcaa
    83281 aatcgttcat atcgatattg agccgacgca aattggtcgc gtgctgtgtc cggatctcgg
    83341 cattgtctct gatgctaaag cggcgctgac actgctggtt gaagtggcgc aggagatgca
    83401 aaaagcgggt cgtctgccgt gtcgtaaaga atgggtcgcc gactgccagc agcgcaaacg
    83461 cactttgctg cgcaaaaccc atttcgacaa cgtgccggtg aaaccgcagc gcgtgtatga
    83521 agagatgaac aaagcctttg gtcgcgatgt ttgctatgtc accaccattg gtctgtcaca
    83581 aatcgctgcg gcacaaatgc tgcatgtctt taaagaccgc cactggatca actgtggtca
    83641 ggctggtccg ttaggctgga cgattccggc tgcgctaggg gtttgtgccg ctgatccgaa
    83701 acgcaatgtg gtggcgattt ctggcgactt tgacttccag ttcctgattg aagagttagc
    83761 tgttggcgca cagttcaaca ttccgtacat ccatgtactg gtcaataacg cttatctggg
    83821 gctgattcgc cagtcgcagc gcgcgtttga tatggactac tgcgtgcaac tcgctttcga
    83881 gaatatcaac tccagtgaag tgaatggcta cggtgttgac cacgtaaaag tagcggaagg
    83941 tttaggttgt aaagcgattc gcgtcttcaa accggaagat attgcgccag cctttgaaca
    84001 ggcgaaagcc ttaatggcgc aatatcgggt accggtagtc gtggaagtta ttctcgagcg
    84061 tgtgaccaat atttcgatgg gcagcgaact ggataacgtc atggaatttg aagatatcgc
    84121 cgataacgca gcggacgcac cgactgaaac ctgcttcatg cactatgaat aagggagata
    84181 aataatgtta cgtttctctg ctaatttatc gatgttattt ggagaatatg attttctcgc
    84241 ccgttttgag aaagctgcgc agtgtggttt tcgcggcgtt gaatttatgt ttccttatga
    84301 ctacgacatt gaagaattaa aacaggtgct ggcgagtaat aaactcgaac atacgctgca
    84361 caatttaccg gcgggtgact gggcggcggg ggagcgcggt attgcctgta ttcctggccg
    84421 tgaagaagag tttcgggatg gcgtagcagc agcgattcgt tatgcccgtg cgctgggtaa
    84481 taaaaaaatt aactgtctgg tcggtaaaac gccggctggt ttcagcagtg aacagattca
    84541 cgcaacgctt gtagaaaacc tgcgttatgc cgcgaatatg ctgatgaaag aagatatttt
    84601 attactgatt gaacctatta accattttga tattcctggt ttccatctca ccggaactcg
    84661 gcaggcgctg aaattgattg atgatgttgg ttgctgcaat ttgaaaattc agtatgacat
    84721 ttatcacatg cagcggatgg aaggtgaatt aaccaacacc atgactcagt gggccgataa
    84781 aattggccac ctgcaaattg ctgataatcc gcatcgcggc gaaccgggga ccggagaaat
    84841 taattatgat tatctcttta aggtaatcga aaattctgac tacaacggtt gggttgggtg
    84901 tgaatataaa ccccaaacca ccacggaagc cggtttacgc tggatggatc cgtaccgtta
    84961 aaacgtaacg ctgttcaggc aatgcttttt taggccgcta agttggcagg ggatcgtgtt
    85021 gtctgaattc aggaaaagcg aaatttaaaa gaggttaatt atgaaactgg gatttattgg
    85081 cttaggcatt atgggtacac cgatggccat taatctggcg cgtgccggtc atcaactgca
    85141 tgtcacaacc attggaccgg ttgctgatga attactgtca ctgggtgccg tcagtgttga
    85201 aactgcgcgc caggtaacgg aagcatcgga catcattttt attatggtgc cagatacacc
    85261 acaggttgaa gaagttctgt tcggtgaaaa tggttgtacc aaagcctcgc tgaagggcaa
    85321 aaccattgtt gatatgagct ccatttcccc gattgaaact aagcgtttcg ctcgtcaggt
    85381 gaatgaactg ggcggcgatt atctcgatgc gccagtctcc ggcggtgaaa tcggtgcgcg
    85441 tgaagggacg ttgtcgatta tggttggcgg tgatgaagcg gtatttgaac gtgttaaacc
    85501 gctgtttgaa ctgctcggta aaaatatcac cctcgtgggc ggtaacggcg acggccaaac
    85561 ctgcaaagtg gcaaatcaga ttattgtggc gctcaatatt gaagcggttt ctgaagccct
    85621 gctatttgct tcaaaagccg gtgcggaccc ggtacgtgtg cgccaggcgc tgatgggcgg
    85681 ctttgcttcc tcacgtattc tggaagttca tggcgagcgt atgattaaac gcacctttaa
    85741 tccgggcttc aaaatcgctc tgcaccagaa agatctcaac ctggcactgc aaagtgcgaa
    85801 agcacttgcg ctgaacctgc caaacactgc gacctgccag gagttattta atacctgtgc
    85861 ggcaaacggt ggcagccagt tggatcactc tgcgttagtg caggcgctgg aattaatggc
    85921 taaccataaa ctggcctgat acccgcaata aaaatggccg atatcagaaa atgaatcggc
    85981 cagcaatatt aaaaaagaaa gcagccaaag atgttgcttc agtattaaaa ataatatttt
    86041 tattttattt gttcctcata gctagattaa aacaacgtta ttcgatacgt gaaattaaga
    86101 gggatttatg gaacatcaga gaaaactatt ccagcaacgc ggctatagcg aagatctatt
    86161 gccgaaaacg caaagccagc ggacctggaa aacatttaac tattttacct tatggatggg
    86221 ttcggttcat aacgttccca attatgtgat ggtcggcggc ttttttattc tcggcttgtc
    86281 tacctttagt attatgctgg caattatcct cagcgccttt ttcattgccg cggtaatggt
    86341 attaaacggc gctgcgggca gtaaatacgg cgtaccgttt gccatgatcc tgcgtgcttc
    86401 ttacggcgta cgtggcgcac tgtttcccgg attattaaga ggcggtattg ctgccattat
    86461 gtggtttggc ctgcaatgtt acgcggggtc actggcctgc ttgattctga ttggcaaaat
    86521 ctggccggga tttttaactc tcggtggtga tttcacgctg ttagggcttt ctctaccggg
    86581 cttaattact ttcttactct tctggctggt caacgttggt ataggttttg gcggtggcaa
    86641 agttttaaat aaattcactg ccattcttaa cccgtgcatc tatatcgttt tcggcggtat
    86701 ggcgatttgg gcgatttcgc tggtcgggct cggtccaatc tttgactaca ttccgagcgg
    86761 tattcagaaa gcagaaaaca gtggattctt gttcctggtg gtgattaacg cggtagttgc
    86821 ggtctgggcg gcaccggcgg tgagcgcatc cgactttacg caaaacgccc actcgtttcg
    86881 tgagcaagcg ctggggcaaa cgctgggttt agttgtggcc tatattcttt ttgcggtcgc
    86941 tggggtatgt attattgccg gagccagtat tcactacggc gctgacacct ggaacgtgct
    87001 ggatattgtt cagcgttggg acagcctgtt tgcctcgttc tttgcggtac tggttattct
    87061 gatgacgact atttccacta acgccaccgg taatattatt ccggccggtt atcagattgc
    87121 tgccattgca ccgacaaaac tgacctataa aaacggcgta ctgattgcca gtattatcag
    87181 cctgctgatc tgcccgtgga aattaatgga aaatcaggac agtatttatc tgttcctcga
    87241 tatcatcggc ggaatgctgg gtccggtaat tggtgtcatg atggcacatt attttgtggt
    87301 gatgcgtggg caaattaatc ttgatgaact gtacaccgca cctggcgatt ataaatatta
    87361 cgataacggt tttaacctca ccgcgttttc agtaactctg gtggccgtta ttttatctct
    87421 tggcggtaag tttattccct ttatggaacc gttatcgcgt gtttcatggt ttgtcggcgt
    87481 catcgtcgcc tttgcggcct acgccttatt aaagaaacgt acaacagcag aaaaaacagg
    87541 agagcaaaaa accataggtt aattaatccc gatattgaac attgagttaa aaaccaatct
    87601 gtattttaca aggagtttgt tatgtctttt gatttaatca ttaaaaacgg caccgttatt
    87661 ttagaaaacg aagctcgcgt tgtagatatc gccgttaaag gcgggaaaat tgctgctatc
    87721 ggtcaggatc tgggcgatgc aaaagaagtt atggatgcgt ctggtctggt ggtttcgccg
    87781 ggcatggttg atgcgcacac ccatatttct gaaccgggtc gtagccactg ggaaggttat
    87841 gaaaccggta ctcgcgcagc ggcaaaaggt ggtatcacca ccatgatcga aatgccgctc
    87901 aaccagctgc ctgcaacggt tgaccgcgct tcaattgaac tgaagttcga tgccgctaaa
    87961 ggcaagctga ctatcgatgc ggcacaactc ggtggcctag tgtcttacaa catcgaccgt
    88021 ctgcatgagc tggatgaagt gggcgttgtc ggcttcaaat gcttcgttgc gacctgtggc
    88081 gatcgcggta tcgacaacga cttccgtgat gtaaacgact ggcagttctt caaaggtgcg
    88141 cagaagctgg gcgaactggg gcagccggtg ctggtgcact gcgaaaacgc gctgatctgt
    88201 gacgcactgg gcgaagaagc gaaacgtgaa ggtcgcgtaa ctgcccatga ctatgtggct
    88261 tcgcgtccgg tatttaccga agtggaagcg attcgccgcg tgctgtatct ggcgaaagtt
    88321 gccggttgcc gtctgcacgt ttgccatatc agcagcccgg aaggcgttga agaagtgact
    88381 cgtgcacgtc aggaaggtca ggacgttact tgtgaatcct gcccgcatta ctttgtactg
    88441 gataccgatc agttcgaaga aatcggcact ctggcgaagt gttcaccgcc gatccgcgat
    88501 ctggaaaacc agaaaggcat gtgggaaaaa ctgtttaacg gtgaaatcga ctgcctggtt
    88561 tccgaccact caccatgccc tccggaaatg aaagccggca acatcatgga agcatggggc
    88621 ggtattgccg gtctgcaaaa ctgtatggac gtgatgttcg atgaagcggt acagaaacgc
    88681 ggaatgtctc tgccaatgtt cggcaaatta atggcgacta acgcagcaga tattttcggt
    88741 ctgcagcaaa aaggccgtat cgccccagga aaagatgccg acttcgtctt cattcagccg
    88801 aatagcagct atgttcttac caatgacgat ctggaatatc gccacaaagt cagcccgtat
    88861 gttggccgta ccattggcgc gcgtatcacg aaaaccatct tacgtggtga tgtgatttac
    88921 gacattgaac agggcttccc tgttgcgccg aaaggtcaat ttatccttaa acatcagcag
    88981 taatctggcc cctgcaatgc ccgtccttgc ggcgggcatt ctccggttaa ggtgtgttta
    89041 tgttcaattt tgcagtgagc cgcgaaagcc tgttatcagg atttcagtgg tttttcttta
    89101 ttttttgcaa cacggttgtg gttcctccta cgctactttc tgcttttcag ttgccgcaaa
    89161 gtagcctgct tacgctcacg caatatgctt ttcttgctac cgcactggcc tgcttcgctc
    89221 aggcgttctg cggtcatcgt cgcgctatta tggaagggcc gggtggcctg tggtggggaa
    89281 ccatccttac tatcaccctt ggcgaagcat cgcgcgggac accgatcaac gatatcgcta
    89341 ccagcctggc ggtggggatt gcgctctccg gcgtgctgac gatgttgatt ggttttagcg
    89401 gattaggcca tcgcctggca cggttattta cgccgtcggt gatggtcttg tttatgttga
    89461 tgctgggcgc gcagctgacc actatctttt tcaaaggtat gctcgggctg ccgtttggca
    89521 tagccgaccc aaattttaaa attcagttac cgccgttcgc gctctcggtg gcggtgatgt
    89581 gcctggtact ggggatgatt atcttcctgc cgcaacgttt tgcccgttat ggcctgctgg
    89641 tcggcaccat aaccggctgg ttgttgtggt acttttgctt tccttcttcg cactcgctct
    89701 ccggtgagtt gcactggcag tggttcccgc tcggcagtgg aggtgctttg tctccgggaa
    89761 ttattctgac ggcggtgatt acaggtctgg tgaatatcag caatacctac ggtgcgattc
    89821 ggggcacgga tgttttttat ccgcagcagg gcgcggggaa tacgcgttat cgtcgcagct
    89881 ttgtggcgac cggatttatg acgctgataa ccgtaccgct ggcggtaatt ccattttcac
    89941 cgtttgtttc atccattggt ttattaaccc agacaggcga ttacacgcgg cgttcgttta
    90001 tttatggcag cgttatttgc ctgctggtgg cgctggttcc ggcactcaca cgactgtttt
    90061 gcagtatccc tttacccgtg agtagcgcgg tcatgctggt ttcttatctg cctttactct
    90121 tttccgcgct ggtgtttagc cagcaaataa cctttaccgc tcgcaatatt tatcgactcg
    90181 cattgccgtt atttgtcggc atatttttaa tggcattacc gcctgtgtat ctgcaagacc
    90241 ttccattaac gctgcgtcct ctgctcagta acggcttact ggtcggaatt ttactggctg
    90301 ttcttatgga taatcttatt ccgtgggaac gcatcgaata atttgttgaa aaaggattga
    90361 taatgaagat tgtcattgcg ccagactctt ttaaagagag cttaagtgca gaaaaatgtt
    90421 gtcaggcaat taaagccggg ttttcgaccc tctttcccga tgcgaactat atctgtttgc
    90481 cgatagcgga tggcggcgaa gggacggtgg atgcgatggt cgccgcgacg ggcggcaaca
    90541 tcgtgacgct tgaagtctgc gggccgatgg gcgaaacagt gaatgctttt tatggcctta
    90601 ccggcgacgg gaaaacggcg gtgattgaga tggcggcagc aagtggcctg atgctggtcg
    90661 cgcctgaaaa gcgtaatccg ttgctggcct ccagttttgg tacgggggag ttaattcgtc
    90721 atgcgctgga taacggcatt cgccatatta ttctcggcat tggcggcagt gcgacggtcg
    90781 acggcggtat gggcatggct caggcgcttg gtgtgcgttt ccttgatgcc gacggccagg
    90841 tgctggcggc taacggcggt aatttagcgc gcgtggcaag cattgagatg gatgaatgcg
    90901 atccgcgtct ggcgaattgc catattgaag tagcatgtga cgttgataac ccgctggtag
    90961 gggcacgcgg cgcggcggcg gtgtttggcc cgcaaaaagg ggcaacgccg gagatggtcg
    91021 aagaacttga acaggggctg caaaattacg cccgtgtttt acaacagcaa actgaaatta
    91081 atgtctgcca gatggcgggc ggcggcgctg cgggcggtat gggtattgcg gcggcggtat
    91141 tcctcaatgc ggatattaaa ccgggtattg agattgtact gcgggcggtc aacctggagc
    91201 aggcggtgca gggcgcagca ctggtgatca ccggggaagg gcgcattgac tcgcaaacgg
    91261 caggcggtaa agcgccgctg ggcgttgcgt cggtggcgaa gcagtttaat gtcccggtga
    91321 ttgggattgc tggcgtattg ggtgatggcg tggaagtggt gcaccagtac ggcattgacg
    91381 cggtattcag cattttgcct cgtctggcac ctttagccga agtgctcgcc agcggtgaaa
    91441 ccaatctctt caacagcgcg cgaaatattg cctgcgccat taaaataggt cagggaatta
    91501 aaaactgacc cttaccttta aagcggatgc gatttatttc gcatcttttt ttacctgaat
    91561 ttactacaaa aaaagccacg gtataaaccg tggcaaaatc caacatagct aaaaataatc
    91621 aggcgagtgg tatgacttaa atctctacgt cgcggttgca atctttcgag taaatatagc
    91681 tgaacgcttc accacgccct acgccataac cagcctgtaa agaataagcg cccataaaga
    91741 tgtaatcgcc ttttttcacc gggatccagt tattgtcgag gttataaacc ccctgaccgg
    91801 aaagaatata ggcaccgtgt tcctgaacat gtgtttcgat ataaccgtgg ctggcacctg
    91861 gtgcaaaaga gaggatatgc atgttcatat caaaacctaa ctctttgggc agaaaatcca
    91921 gcaggatcac atcatccata ccttcatagt gaatgcgttc cagttcgctg gcattgccag
    91981 aaaccagcca cggtgcatgg ccttctaccg gaacatagcg acgcttatat aaaaagattt
    92041 ggctgtcttc ggcctgggcg ttaacaaacg tcattaagga gcctggtggg caataaagat
    92101 agccaccttc gcttaaggca aatgttttgc cttcggcttt ggcagtgata tttccagaga
    92161 tcacatacag gaacgtttca atgccttcgc caccgaagcc ctgttggttg ccaccgtttt
    92221 gatgcagtgt gaccagataa tcaacaaaag aggcacccag ctttggcgtg gagaggattg
    92281 tcgcgtcaca attttcaaag cccggaataa tattttttac cagaccatcc ggggttaaca
    92341 gtgcgaaatt accgtgttta acaatcgcac ggttagccag taaatcatcg cggtaaccgg
    92401 tgacgttatt taaatatccc atttatgact ccttatttct gccaggcaag ttgataaagc
    92461 atgagtgcca acgttttgac cccttcggca aggtcggtaa tattggtgcg ttccgccggg
    92521 ttatggctga tcccgttgat gctgggaatg aaaatcatgc aggttggtac gcgaggcgcg
    92581 aaaatttgcg cgtcgtgccc ggcaccactg tgcatcaccc ggtaattcag tttttctctt
    92641 tcacacaatt ctgtcagggt ggcgaccagc tccttattca tcggcacggg ttcttcgtcc
    92701 atccataaat cgatatcaat accaatgtcc atttcatcgc aaatcgcccg catgtcgttt
    92761 tctaactgtt gggtgaaatc gcgcagcacg gcagcgtcgg tatgacgaca atcaatggtg
    92821 aacgtggttt tacccggcac cacatttacc gtattcgggc gcggctctac tttgccaaag
    92881 gtcagaacca gcggatcgcc catccttttc gctttttcga ccgactgatg gcaaatgcga
    92941 ctgaaagcgt aaactgtatc acgacgataa cccatcggcg tggtgcctgc atggtttgat
    93001 tcgccgttca gcgttaccgt ataacgacgc tgcccgacaa ttgcattcac cacgccaatt
    93061 gattgcccat tactttccag cacacagccc tgttcaatat gcagttcaac aaaggcttta
    93121 atatcctgac gcggagttag tggggcgttc ggaagagtaa atccgcaagc cttcatcgca
    93181 tcgacaaaac tatttccttt ggcatcacag atattccgca cgtcgtcagg attcgccagc
    93241 ccaaagatat ttttactgcc ccagaagaca tacgggaagc ggctgccttc ttcttctgcc
    93301 atcgccacca cttcgaccgt acgtagcggc gcgccgtatt gcgttttcag ccagtcaatt
    93361 gccagccacg ccgccagcgc gccgaattgc ccgtcgaggt taccgccgtt aaccacggta
    93421 tcgatatgcg aaccgctcag aaccacttct tgtggatatt cggtgccact caggcgacca
    93481 tataaattcc ccacttcatc gaaacgtgtt tccagcccgc ttgctgccat tcttttttta
    93541 aattgctgct gagtttccag ccattccggc gaataaagta aacgggtcat accacccgtt
    93601 gggtcagcgc caaaagagga aagccagggc agcgtttctt ctatggcttg acgaaaatgt
    93661 gtaatcataa gaaagtcctg tctcaataat tattgcgcaa agggattttt cgtttcgtat
    93721 gacgtgttat aaagcgcgtc ggaaattaaa tactggtaaa tatcatcaac aatttcgatg
    93781 ccttcgacgg cggctttgcg ttgtttaata tcctgatcct gtccgggata ataaacctga
    93841 ttaaaaccgg gcgcgggggt aatggcattt aattcgcgca tggtctggct aagatgttga
    93901 cgaaataatt tgctggagaa gaaaaagttc gggttaataa cgatatgtaa ttgccccaaa
    93961 ttacgcccgg cgtgtaaatc gtcatacatc gaactaacct gtcgcccgaa cggtaagccg
    94021 agtaagacgc ctgagaggac gtcaatcatc atcatcaggc catacccttt tggcccggcg
    94081 gcggggagca gagcatgtac cgcgaacgga tcggttgttg gtgcaccgtt tttatcgacc
    94141 gcccaggtat ccgggataga catattacgc gagcgggcgt cgagcacttt tccccatgcc
    94201 tgtacggtag tcgccatatc aaaggtaagg atctcgtcgc cttctcccgg cgcggcaaag
    94261 gccagtgggt tagtaccgta gtaaatttcc gcgccgccaa acggcaccac cattggatcg
    94321 gactggcaca tcgaaatacc aattaatccg gcgcgggctg cctgctgcac aaaataagag
    94381 attgcgccgc tgtgacccat ccggctgata ccgaccaccg caacgccatt ttgctgggcg
    94441 gttttgatgg catgttccat acccattttc gccgcgacct gtccggcggc attgtcggca
    94501 tgtaaaattg ccgagcacgg cccggtttcc tcaagacgaa actccggttc gcggttggtg
    94561 ccgccttttg aaatgcgttc cgcgtagtat tccacgcgca ccgcgccatg agagtggatc
    94621 cctctggcat cggcgtaaac caatacttca gccacggttg cagcgtgctc acgttttaac
    94681 ccagcctggc agagtttatt ctcaattagc tggtggagtg tttcccgact gattttcatc
    94741 tgtcttcctt tttaacgacg gtgtgaagca tgactgcaat taacatacag ggaaaatatc
    94801 tggattatgt gatccagaca ggcaaaaaaa tatagttaga atttatttga taatccgctc
    94861 gcttttaacc tggtttttaa aacaaccacg cttattaaaa aataacacgt aatagcatgg
    94921 cggttatttg aattcttttg ttaataatcc ctgtgtgata ttcatcacct tatttatccg
    94981 ttgtcatcga taccgtaatc gccacattaa cactgctcgt gcaattgcca tgggtgcaat
    95041 ttttaaggag ttgttatgat ccacgccttt attaaaaaag ggtgttttca ggattcggtc
    95101 agtttaatga ttatttcacg aaaactcagc gaatcagaaa atgttgatga tgtttccgta
    95161 atgatgggta cgcccgccaa taaagcgtta ttagatacca caggtttctg gcatgacgat
    95221 tttaataacg ccacgccgaa cgatatttgc gtggcaatac gtagcgaagc ggcggatgcg
    95281 gggatcgcgc aggcgattat gcagcagctt gaagaggcgc taaaacaact ggcgcagggg
    95341 tcaggcagca gccagtcctt gacgcaggtg cgtcgctggg acagtgcctg tcagaaatta
    95401 tccgatgcca atctggcgct gatttcagtg gctggcgagt atgcggcgga gctgacaaac
    95461 caggcgctgg atcgcaacct caacgtgatg atgttctccg ataacgtcac gctggaagat
    95521 gaaatccaac ttaaaacccg cgcgcgggaa aaaggcttgc tggtgatggg gccggactgc
    95581 ggtacgtcga tgattgccgg cacaccgctg gcttttgcta acgtgatgcc agaaggcaat
    95641 attggcgtca ttggcgcttc cggtaccggg attcaggagc tgtgttcgca gattgcgctg
    95701 gcaggggagg gaattactca cgcgattggc cttggcgggc gcgacctcag ccgtgaagtg
    95761 ggcggcatca gtgcgctaac agcgctggaa atgctcagtg cagacgagaa aagcgaagtg
    95821 ctggcatttg tttcaaaacc acctgccgaa gctgtgcgtc tgaaaattgt taatgccatg
    95881 aaagcaaccg gcaaaccgac ggtggcgctg tttttaggtt ataccccggc ggtggcacgc
    95941 gacgagaatg tctggtttgc ctcctcgctg gatgaggccg cacgcctggc ttgcctgctt
    96001 tcacgcgtta cggcgcgacg taacgcgata acgcctgcca gcagcggatt tatttgcggt
    96061 ttgtataccg gcggtacgct ggctgccgaa gcggcgggat tacttgctgg acaccttggc
    96121 gtggaagccg acgataccca tcatcacggc atgatgctcg acgccgatgg tcaccagatt
    96181 attgacctcg gcgatgattt ctacaccgtc gggcgtcccc atccgatgat cgacccagcc
    96241 ttacgcaatc agttaattgc cgatctcggc gctaaaccgc aagtgcgcgt attgctgctt
    96301 gatgtcgtga ttggcttcgg tgcgaccgcc gatccagccg cctcgctggt aagcgcctgg
    96361 caaaaagcat gtgccgcgcg ttcagacaat caaccactgt atgccattgc cacggtgaca
    96421 ggcactgaac gtgacccgca atgccgctcg cagcaaatcg ccacgctgga agatgcaggg
    96481 atcgcggtag tgagttcgct gccggaagcc accttgctgg cggcggcact gattcgtccg
    96541 ctttcgcctg ccactcagca acacacaccg tcattactgg aaaacgtcgc cgtgattaac
    96601 atcggattac gcagctttgc gctggagcta caaagcgcca gcaaaccggt tgtgcattac
    96661 caatggtcgc cagtcgccgg cggcaataaa aaactggctc gtttattaga acgtttgcaa
    96721 taaggggttc ccatgtttac atcagtggcg caagccaatg ctgcggttat cgaacaaatt
    96781 cgtcgcgctc gtccacactg gctggatgtg caaccggctt cttcacttat cagcgaacta
    96841 aacgagggca aaacactgct tcacgccggg ccgccaatgc gctggcagga gatgaccgga
    96901 cccatgaaag gggcgtgcgt gggcgcatgt ctgttcgaag gctgggcgaa agatgaagcg
    96961 caggcgctgg caatactgga gcagggggaa gtgaacttca ttccttgtca ccatgtgaat
    97021 gccgtcgggc caatgggcgg cattacttct gccagtatgc cgatgctggt ggtcgagaac
    97081 gtgaccgacg gcaaccgggc gtactgcaac ctcaacgaag gtatcggcaa agtgatgcgt
    97141 tttggcgctt acggcgaaga tgtcctgact cgccatcgct ggatgcgcga tgtgttaatg
    97201 ccagtattaa gcgcggcgct ggggcgcatg gagcgcggta tcgatctcac ggcgatgatg
    97261 gcgcagggca ttacgatggg cgatgagttc catcaacgca atattgcttc ctctgcactg
    97321 ttaatgcgtg cgctggcccc acaaattgct cgcctcgatc atgataaaca gcacatcgcc
    97381 gaagtgatgg atttcctcag cgtgaccgat cagttcttcc tcaacctcgc gatggcttac
    97441 tgcaaggcgg cgatggatgc tggcgcgatg atccgcgcag gcagcatcgt cacggcaatg
    97501 acccgcaacg gcaatatgtt cgggattcgg gtaagcgggc tgggcgaacg ctggtttact
    97561 gcgcctgtaa acactccgca aggtctgttt ttcaccggct tctcgcagga gcaggcgaac
    97621 ccggatatgg gcgatagcgc gattaccgaa acctttggta tcggaggtgc ggcaatgatc
    97681 gcagcgcctg gcgtaacgcg ctttgtcggt gcgggtggca tggaagcggc cagagcggta
    97741 tctgaagaga tggcggaaat ttaccttgag cgcaatatgc agttgcagat cccaggctgg
    97801 gattttcagg gcgcgtgcct gggactggac attcgtcgcg tggtagaaac cggcattacg
    97861 ccactcatca ataccggtat cgcccataaa gaggcgggga tcgggcagat tggcgcaggc
    97921 actgtgcgag caccgctggc gtgttttgaa caggcgctgg aagcactggc tgaaagcatg
    97981 gggattggtt gaggaacgcg caatgacgat catccatcct ctgcttgcca gccgtagtgc
    98041 accgaattat cgccagtcct ggcggttagc gggagtgtgg cgacgggcga ttaacctgat
    98101 gacggaaagc ggcgaactgt taacgctgca tcgtcagggt agtggtttcg gccccggagg
    98161 atgggtgctt cgccgcgcgc aattcgatgc gttatgcggt ggattatgcg gcaatgaacg
    98221 accacaggtt gtggctcaag ggattcgcct cgggcgtttc acggttaaac agccacagcg
    98281 ttattgtttg ctgcgtatta cgccgccttc gcatcctcaa ccgcttgcag ctgcatggat
    98341 gcaacgcgcg gaggaaaccg gacttttcgg accactggcg atggcggcaa gcgatccgct
    98401 gcccgctgaa ttacgccagt ttcgtcactg ttttcaggcc gcgctcaatg gcgttaagac
    98461 cgactggcgg cactggctgg gtaaaggccc cggattaacg ccaagtcatg atgacacgtt
    98521 gagcggaatg ctgctggcgg cctggtatta tggcgcttta gatgcgcgcg ccggtcgccc
    98581 gttttttgcc tgttccgaca atcttcaact cgttaccaca gcggtgagcg tcagttattt
    98641 acgttatgcc gcgcaaggat atttcgcctc gccactcctg cactttgtcc atgctctgag
    98701 ttgcccgaaa cgtaccgctg ttgcgattga ttcgctgctg gcgctggggc atacgtcagg
    98761 ggcagatacg ctgctggggt tctggcttgg ccaacaatta ttacaaggaa aaccatgaaa
    98821 acactggttg tagctcttgg gggcaacgcc ttactccagc gcggtgaggc gctgacggcg
    98881 gaaaatcaat atcgcaatat cgccagtgct gtacccgcgc tggcacgcct ggcccgttct
    98941 tatcggctgg cgattgttca cggcaacggg ccgcaggtgg ggctgctggc gttacagaat
    99001 ctggcgtgga aaaaggtaga accgtatccg ctggatgtgc tggtggcgga aagccagggg
    99061 atgattggct atatgctggc gcagagcttg agcgcacagc cgcagatgcc gcctgttacg
    99121 acggtgctga cgcgcattga ggtttcgcct gatgatccgg cgtttttgca gccagagaaa
    99181 tttattggtc cggtttatca gccagaagaa caagaggcac tggaagcggc ttacggctgg
    99241 cagatgaaac gtgatggtaa atatttgcgc cgggtggtgg cgtctccgca accgcgtaaa
    99301 attctcgaca gcgaagccat cgagttgttg ctcaaagagg ggcatgtggt gatttgcagt
    99361 ggcggcggcg gtgtgcctgt gacggaagac ggggcaggga gtgaagcggt gattgataaa
    99421 gatctcgccg ctgccttgct tgccgagcag attaacgccg atgggctggt gatcctcacc
    99481 gatgctgatg cggtatatga aaactgggga acgccgcagc aacgcgccat tcgccatgcc
    99541 acaccggatg agttagcgcc atttgccaaa gccgatggtt cgatggggcc gaaggtaacg
    99601 gcggtgagtg gttatgtcag aagccgtggt aaacccgcgt ggattggggc gttatcgcgg
    99661 attgaagata cgctggcggg cgaagcaggg acctgtattt cgctgtagtg atgagagcat
    99721 ccggcaatcg gtgcaccatg cctgatgcga cgcttgacgc gtcttatcag gcctacaatg
    99781 ggtaccggag cggtaagccg gataaggcgt ttacgccgca tccggcaatc aaatgagcac
    99841 ctgcttaact gaacttactc tgcgcccaaa tcacgccgct ggcatactct ggcggcagca
    99901 gcgggattaa ggcttccagc gtcgcagtca gacgcgatgt gtcgctgtcg gtcaaattca
    99961 gatgccccac tttacgcccc ggacggactt ctttgtcgta ccagtgcaga tgcaccagcg
   100021 gcaatttcag ccagtcataa ttcacatcgc taccaatcag attgatcatc accgacggat
   100081 tattcactac tggttgcggt aacggcagat cggtaatcgc ccgcagatgc agctcaaact
   100141 ggctgatgct ggcaccgttt tgtgtccagt gaccgctgtt atgcacacgc ggtgccagtt
   100201 cgttgatcaa cagaccttgc ggggtgacaa aacactccat cgccatcacg cccacatagc
   100261 ccagctcctg cataatcgcc gacagcatct cttcggcttg cgcctgctgc tgtgcgttgg
   100321 cctgcggaaa agcgacgctg gtgcgcaaaa taccgtcctg atgcaggtta tgcgtcagcg
   100381 gataaaacac ggtgctgcca tcaaagccgc gcgcgccaac cagcgacact tcaccagaga
   100441 agttaatgcc ctgctcgaca atacattcgc cgtaacactc tgccggtaac tgttcggttt
   100501 cattggcgcg taaacgccat tgaccgcgac cgtcatagcc accagtgcga cgcttaacaa
   100561 tcgccagttc acctaaacga tcaaacaccg caggccactc gctgcgatcg gcaagtaact
   100621 gccacggcgc ggtcggcagg tggagcttat cgaaaagctg cttctgagtc agacggtcag
   100681 caataatcgg gaacacatcg cggttcacaa aggccggatg acgcgccagc tcgcgggtta
   100741 atgcggtttc cggccagcgt tcgatctcag cggtaatcac gctttgttga aaaggcaccg
   100801 ccgccggttc agcgtccagc ccgaccggcc agacagcaat gcctaacggt tcgcctgcct
   100861 gacgcagcat acggcctaac tgcccgttac cgaggacgca aacctgtttc atgccgcacc
   100921 tcgcgggtcc gggttttcca gcacttcgtc ggtctgggct ttgcgccagt catttagacg
   100981 ctggtgtagc tctttatcgt gagtcgcgag aatttgtgct gccagtaatg ccgcgtttgc
   101041 cgcgccagct ttaccaatcg ccagcgtacc caccggaatg ccgcgcggca tttgtacgat
   101101 ggagtagagg ctatcgacac cgctcagtgc ggcgctctgt actggcacgc ccagcaccgg
   101161 caccagcgtt ttggcggcaa tcatgcctgg caggtgcgct gcgccacctg cgcccgcaat
   101221 aatcacctga taaccgttct cttcggcgct ttcggcgaag ctgaacagtt tatcgggggt
   101281 gcggtgagca gaaaccactt caacgtggtg cgggacattc aggatttcga agatttcggc
   101341 ggcgaactgc atggtagccc agtcgctttt ggaccccatc acgatggcga cacgcgccgg
   101401 attattgcgg gaagacatgc gtcttaaaac tcctgtggtg cacaactctc ggctttagag
   101461 ggcacagaga atagcacgga aagagagcaa ggaaaacggt tgcgtggctg tgaaatcagc
   101521 aaagttgcgg gttttttaaa acggaaaatg aatcagctca acgtcatccg ccgtgacttt
   101581 caccatcgaa ccttccgtat gccaggcacc gagtaccacg cgaaaagcag gttgctggtt
   101641 ggcgataagt tcatgtaccg ccgggcgatg ggtatgtccg tggatcagcc attgcacctg
   101701 atgtttttcc atcgcactga ctaccgcgtt ttggttaacg tccatgatcg ccagcgattt
   101761 actgctgttg gcttctttac tgttcgctcg cattcgcgcg gcaatgcgtt tgcgcacaaa
   101821 caacggcagg gcgaggaata gcatttgcag ccagggtttg tggactttgg cgcgaaaagc
   101881 ctgataaccc gcgtcatcgg tgcacagcgt gtcgccatgc ataatcaaca cccggcgacc
   101941 ataaagttcg agcacctttt cttccggcaa taatgtcatg ccgctttcac gggcaaagcg
   102001 tttgccgagc agaaaatcac ggttgccatg aatgaaataa cagggaacgc cggaatcgga
   102061 caccgctttg atcgctgccg ccatctggcg atggagtggg ttgggatcgt cgtcgccaat
   102121 ccatgcttca aacagatcgc caagaatata cagcgcgtcg gccttgcggg cttcccccgc
   102181 taaaaaacgc agaaaaccgg cggtgatcgc cggttcttcc acgcagagat gaagatctgc
   102241 aataaagagt gtcgccacga ttactcgcta acggtcacgc tttcaatgat aacgtcttct
   102301 tttggcacgt cctggtgcat accgctacga ccggttgcaa cacctttgat tttgtctacc
   102361 acgtccatgc cttcaaccac ttcagcaaac acgcagtagc cccaaccttg caggctttcg
   102421 ccagagaagt tcaggaagtc gttatcaacc acgttgatga agaactgtgc agttgcagag
   102481 tgcggagcct gagtacgggc cattgccagc gtaccacggg tatttttcag accgttgttg
   102541 gcttcgtttt tgatcggttc tttggtggct ttttgtttca tgcccggttc aaaaccgccg
   102601 ccctgaatca taaagccgtt gataacacgg tggaaaatgg tgttgttgta aaaaccttcg
   102661 cggcagtagt ccaggaagtt tttaactgtt tcaggtgctt tatcgtcaaa agttttgatg
   102721 acaatatcgc cgtgattggt gtggaaagta accatttttg catcctgttc cgtttgattg
   102781 gtgcttcaac ccagttcggg tcatatatag ggtggtgtta tagcataacc gcacgatcgg
   102841 atcatcacgc aatgtatgct gattcgcgcg ggaaatatgg gtattatacg caactcaatt
   102901 acccacacat gtctaaacgg aatcttcgat gctaaaaatc ttcaatactc tgacacgcca
   102961 aaaagaggaa tttaagccta ttcacgccgg ggaagtcggc atgtatgtgt gtggaatcac
   103021 cgtttacgat ctctgtcata tcggtcacgg gcgtaccttt gttgcttttg acgtggttgc
   103081 gcgctatctg cgtttcctcg gctataaact gaagtatgtg cgcaacatta ccgatatcga
   103141 cgacaaaatc atcaaacgcg ccaatgaaaa tggcgaaagc tttgtggcgc tggtggatcg
   103201 catgatcgcc gaaatgcaca aagattttga tgctttgaac attctgcgcc cggatatgga
   103261 gccgcgcgcg acgcaccata tcgcagaaat tattgaactc actgaacaac tgatcgccaa
   103321 aggtcacgct tatgtggcgg acaacggcga cgtgatgttc gacgtcccga ccgatccgac
   103381 atatggcgtg ctgtcgcgtc aggatctcga ccagctgcag gcaggtgcgc gcgttgacgt
   103441 ggtcgacgac aaacgcaacc cgatggactt cgttctgtgg aagatgtcga aagagggcga
   103501 accgagctgg ccgtctccgt ggggcgcggg ccgtccaggc tggcacattg aatgttcggc
   103561 aatgaactgc aagcagctgg gtaaccactt tgatatccac ggcggcggtt cagacctgat
   103621 gttcccgcac cacgagaacg aaatcgcgca gtccacctgt gcccatgatg gccagtatgt
   103681 gaactactgg atgcactcgg ggatggtgat ggttgaccgc gagaagatgt ccaaatcgct
   103741 gggtaacttc tttaccgtgc gcgatgtgct gaaatactac gacgcggaaa ccgtgcgtta
   103801 cttcctgatg tcgggccact atcgcagcca gttgaactac agcgaagaga acctgaagca
   103861 ggcgcgtgcg gcgctggagc gtctctacac tgcgctgcgc ggcacagata aaaccgttgc
   103921 gcctgccggt ggcgaagcgt ttgaagcgcg ctttattgaa gcgatggacg acgatttcaa
   103981 caccccggaa gcctattccg tactgtttga tatggcgcgt gaagtaaacc gtctgaaagc
   104041 agaagatatg gcagcggcga atgcaatggc atctcacctg cgtaaacttt ccgctgtatt
   104101 gggcctgctg gagcaagaac cggaagcgtt cctgcaaagc ggcgcgcagg cagacgacag
   104161 cgaagtggct gagattgaag cgttaattca acagcgtctg gatgcccgta aagcgaaaga
   104221 ctgggcggcg gcagatgcgg cgcgtgaccg tcttaacgag atggggatcg tgctggaaga
   104281 tggcccgcaa gggaccacct ggcgtcgtaa gtaattgcgc tgttgccgga tgcgagtttt
   104341 cgcatccggt tatcgcctgc gccaccacaa cattcccata agcaccatcc ccggcaacca
   104401 cacccacatc aattcagaaa ttatcacctg atgcccgtac ggcgtggtgt aacgagacaa
   104461 tgcaaacggc gcgactttaa tcacctgcca gggagcgaaa aagcgttcat ctgaccacgg
   104521 ccacagccag ccaacgccct taccgccagt ggttaccgaa tccagcaagc tgtgcgatag
   104581 caacgagacg gttaaaaaca gccagcagcg aatcagccca gccctgaacc atcggcgtcc
   104641 aatcagcaca cataacagcg ggacaacaaa cgcaaacacc agcgaatggg taaacccgcg
   104701 atgaccaaaa acattgccgt aagcaacgcc aaatttaaac gacaatacgt cggcgtcggg
   104761 cagcatcgcc aggatgattc cggcaaataa cagacgcgga gggatgactt tcgaacccaa
   104821 ccctaaacca atgcataggg gaacagcggc gtgcgtaata acggttggca tgatggtcgc
   104881 ttcggcaaaa tgtcgatgct atcagcatgg atgaacgggg cgtagagggc aaaagtctga
   104941 aaagagaacc ggcctgttga tacaggccgg gaaagggatc aggcaacaac ctgtacgctg
   105001 tgacctgcaa aactcactgt ctgaccggcg acgattttgc agcgtttgcg cgtttcaacc
   105061 gcaccgtcga ctttcacctg gccttcggca atcgcgattt tcgcctgcgc gccgctttcg
   105121 ctccagcctt ccagtttcag caagtcgcac agctcaacgt gcggatgttt acctaaagaa
   105181 aatgtcgcca tgttactcat cctgtggatc atgatattca acgcacgcct gtagcgtgtt
   105241 ttcaatcagc gtggcaaccg tcatcgggcc aacgccgccg ggaacaggcg taatgtatga
   105301 ggcgcgttta gccgcgtctt caaacacgac gtcgcccaca actttgccat tttccagacg
   105361 gttgatgccg acatcaatca caattgcgcc ttctttgatc cagtcaccag gaataaagcc
   105421 cggcttgccg acggcaacga tcaacagatc ggcattttct acgtggtgac gcagattttt
   105481 agtgaaacgg tgagtcacgg tagtggtgca acctgcgagc aacagttcca tgctcattgg
   105541 acgaccgacg atattcgatg cgccaatcac cacggcgttg aggccgaagg tatcaatgtt
   105601 gtaacgctca agcagcgtga cgataccgcg cggggtgcag ggacgcagac gcggcgcgcg
   105661 ctggcacaga cgaccgacgt tataaggatg gaaaccgtcc acgtctttgt ccggatgaat
   105721 acgttccagc actttgacgt tatcaatacc cgccggtaac ggcagttgaa ccagaatgcc
   105781 atcgatggtg ttgtcggcat tcagcgcatc gataagctcc aacagctccg cttcgctggt
   105841 ggtttccggg aggtcataag agcgggagac gaacccgact tcttcacaag ccttgcgttt
   105901 gcttgcgaca taaatttgcg atgcagggtt actacccacc agcacaacgg ccagtcctgg
   105961 tgcccgcagt ccggctgcaa tacgcgcctg aactttttga gcaacttcag agcgcacctg
   106021 ctgcgcaatc gttttaccgt caataatctt tgctgccatc agagagagga ttccatctgt
   106081 tacgtaggtc gaaggggatg cgcctatttt gtcagaagcg gggcgcgctg tcaggtttcg
   106141 tttcagattt atcgcgtgaa gcgacctctt gcgaaggtta ggcgcaccgt cgctgaggtc
   106201 gctgagattg aaagcttcat ttttcgtcca tgatggcgtt gtaaatctgg aactgattta
   106261 tttccttgtt taaggattaa gataatttaa gaaatacctg acaatataaa aagaa
//
LOCUS       DAPGUL010000002        97103 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.002, whole genome shotgun sequence.
ACCESSION   DAPGUL010000002 DAPGUL010000000
VERSION     DAPGUL010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 97103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 97103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..97103
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.002"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(147..1412)
                     /locus_tag="RHX21_000099"
     CDS             complement(147..1412)
                     /locus_tag="RHX21_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1479 domain-containing protein"
                     /protein_id="HDV1985346.1"
                     /translation="MASTFTSDTLPADHKAAIRQMKHALRAQLGDVQQIFNQLSDDIA
                     TRVAEINALKAQGDAVWPVLSYADIKAGHVTADQREQIKRRGCAVIKGHFPREQALGW
                     DQSMLDYLDRNRFDEVYKGPGDNFFGTLSASRPEIYPIYWSQAQMQARQSEEMANAQS
                     FLNRLWTFESDGKQWFNPDVSVIYPDRIRRRPPGTTSKGLGAHTDSGALERWLLPAYQ
                     RVFANVFNGNLAQYDPWHAAHRTEVEEYTVDNTTKCSVFRTFQGWTALSDMLPGQGLL
                     HVVPIPEAMAYVLLRPLLDDVPEDELCGVAPGRVLPVSEQWHPLLIEALTSIPKLEAG
                     DSVWWHCDVIHSVAPVENQQGWGNVMYIPAAPMCEKNLAYAHKVKAALEKGASPGDFP
                     REDYETNWEGRFTLADLNIHGKRALGMDV"
     gene            complement(1564..2379)
                     /gene="ybiV"
                     /locus_tag="RHX21_000100"
     CDS             complement(1564..2379)
                     /gene="ybiV"
                     /locus_tag="RHX21_000100"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase YbiV"
                     /protein_id="HDV1985347.1"
                     /translation="MSVKVIVTDMDGTFLNDAKTYNQPRFMAQYQELKKRGIEFVVAS
                     GNQYYQLISFFPELKDEISFVAENGALVYEHGKQLFHGELTRHESRIVIGELLKDKQL
                     NFVACGLQSAYVSENAPEAFVALMAKHYHRLKAVKDYQEIDDVLFKFSLNLPDEQIPL
                     VIDKLHIALDGIMKPVTSGFGFIDLIIPGLHKANGISRLLKRWDLSPQNVVAIGDSGN
                     DAEMLKMARYSFAMGNAAENIKQIARYATDDNNHEGALNVIQAVLDNTSPFNS"
     gene            complement(2525..4957)
                     /locus_tag="RHX21_000101"
     CDS             complement(2525..4957)
                     /locus_tag="RHX21_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HDV1985348.1"
                     /translation="MTTLKLDTLSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHL
                     DKPIPVRRALALAHHLANRTIWIKHDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDL
                     ADRPGAGFAVSEENKRVLHEVCPWWRGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMT
                     SGDAHLAVNFPLLLEKGLDGLREKVAERRSRINLTVLEDLHGEQFLKAIDIVLVAVSE
                     HIERFAALAREMAATETRESRRDELLTMAENCDLIAHQPPQTFWQALQLCYFIQLILQ
                     IESNGHSVSFGRMDQYLYPYYRRDVELNQTLDREHAIEMLHSCWLKLLEVNKIRSGSH
                     SKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLSYAILESCGRLRSTQPNLSVRYHAGM
                     SNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLGIEPQDAYDYAAIGCIETAVGGKW
                     GYRCTGMSFINFARVMLAALEGGRDATSGKVFLPQEKALSAGNFNNFDEVMDAWDTQI
                     RYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAKSIKQGGAKYDWVSGLQVGI
                     ANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQLRQRLINGAPKYGNDDDT
                     VDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISANVPFGAQTMATPDGRK
                     AHTPLAEGASPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQKLNPATLENESDKQK
                     LMILLRTFFEVHKGWHIQYNIVSRETLLEAKKHPDQYRDLVVRVAGYSAFFTALSPDA
                     QDDIIARTEHML"
     gene            complement(4963..5862)
                     /locus_tag="RHX21_000102"
     CDS             complement(4963..5862)
                     /locus_tag="RHX21_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415345.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HDV1985349.1"
                     /translation="MIFNIQRYSTHDGPGIRTVVFLKGCSLGCRWCQNPESRARTQDL
                     LYDARLCLEGCELCAKAAPEVIERALNGLLIHREKLTPEHLTALTDCCPTQALTVCGE
                     VKSVEEIMTTVLRDKPFYDRSGGGLTLSGGEPFMQPEMAMALLQASHEAGIHTAVETC
                     LHVPWKYIAPSLPYIDLFLADLKHVADAPFKQWTDGNAARVLDNLKKLAAAGKKIIIR
                     VPLIQGFNADETSVKAITDFAADELHVGEIHFLPYHTLGINKYHLLNLPYDAPEKPLD
                     APELLDFAQQYACQKGLTATLRG"
     gene            5993..6655
                     /gene="fsa"
                     /locus_tag="RHX21_000103"
     CDS             5993..6655
                     /gene="fsa"
                     /locus_tag="RHX21_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415346.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDV1985350.1"
                     /translation="MELYLDTSDVVAVKALSRIFPLAGVTTNPSIIAAGKKPLDVVLP
                     QLHEAMGGQGRLFAQVMATTAEGMVNDARKLRSIIADIVVKVPVTAEGLAAIKMLKAE
                     GIPTLGTAVYGAAQGLLSALAGAEYVAPYVNRIDAQGGSGIQAVTDLHQLLKMHAPQA
                     KVLAASFKTPRQALDCLLAGCESITLPLDVAQQMISYPAVDAAVAKFEQDWLGAFGRT
                     SI"
     gene            complement(6834..7583)
                     /gene="moeB"
                     /locus_tag="RHX21_000104"
     CDS             complement(6834..7583)
                     /gene="moeB"
                     /locus_tag="RHX21_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-synthase adenylyltransferase MoeB"
                     /protein_id="HDV1985351.1"
                     /translation="MAELSDQEMLRYNRQIILRGFDFDGQEALKDSRVLVVGLGGLGC
                     AASQYLASAGVGNLTLLDFDTVSLSNLQRQTLHSDATVGQPKVESARYALTRINPHIA
                     ITPVNALLDDAELAALIAEHDLVLDCTDNVAVRNQLNAGCFAAKVPLVSGAAIRMEGQ
                     ITVFTYQDGEPCYRCLSRLFGENALTCVEAGVMAPLIGVIGSLQAMEAIKLLAGYGKP
                     ASGKIVMYDAMTCQFREMKLMRNPGCEVCGQ"
     gene            complement(7583..8818)
                     /gene="moeA"
                     /locus_tag="RHX21_000105"
     CDS             complement(7583..8818)
                     /gene="moeA"
                     /locus_tag="RHX21_000105"
                     /EC_number="2.10.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HDV1985352.1"
                     /translation="MEFTTGLMSLDTALNEMLSRVTPLTAQETLPLVQCFGRILASDV
                     VSPLDVPGFDNSAMDGYAVRLADIASRQPLPVAGKSFAGQPYHGEWPAGTCIRIMTGA
                     PVPEGCEAVVMQEQTEQTDNGVRFTAEVRSGQNIRRRGEDISAGAVVFPAGTRLTTAE
                     LPVIASLGIAEVPVIRKVRVALFSTGDELQLPGQPLGDGQIYDTNRLAVHLMLEQLGC
                     EVINLGIIRDDPHALRAAFIEADSQADVVISSGGVSVGEADYTKTILEELGEIAFWKL
                     AIKPGKPFAFGKLSNSWFCGLPGNPVSATLTFYQLVQPLLAKLSGNTASGLPARQRVR
                     TASRLKKTPGRLDFQRGVLQRNADGELEVTTTGHQGSHIFSSFSLGNCFIVLERDRGN
                     VDVGEWVEVEPFNALFGGL"
     gene            9022..9987
                     /gene="iaaA"
                     /locus_tag="RHX21_000106"
     CDS             9022..9987
                     /gene="iaaA"
                     /locus_tag="RHX21_000106"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HDV1985353.1"
                     /translation="MGKAVIAIHGGAGAISRAQMSLQQELRYIEALSAIVETGQKMLE
                     AGESALDVVTEAVRLLEECPLFNAGIGAVFTRDETHELDACVMDGNTLKAGAVAGVSH
                     LRNPVLAARLVMEQSPHVMMIGEGAENFAFARGMERVSPEIFSTPLRYEQLLAARKEG
                     ATVLDHSGAPLDEKQKMGTVGAVALDLDGNLAAATSTGGMTNKLPGRVGDSPLVGAGC
                     YANNASVAVSCTGTGEVFIRALAAYDIAALMDYGGLSLAEACERVVMEKLPALGGSGG
                     LIAIDHEGNVALPFNTEGMYRAWGYAGDTPTTGIYREKGDTVATQ"
     gene            9974..11845
                     /gene="gsiA"
                     /locus_tag="RHX21_000107"
     CDS             9974..11845
                     /gene="gsiA"
                     /locus_tag="RHX21_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415350.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter ATP-binding protein
                     GsiA"
                     /protein_id="HDV1985354.1"
                     /translation="MPHSDELDAGNVLAVENLNIAFMQDQQKIAAVRNLSFSLQRGET
                     LAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLQRRSREVIELSEQSAAQMRHVR
                     GADMAMIFQEPMTSLNPVFTVGEQIAESIRLHQNASREEAMVEAKRMLDQVRIPEAQT
                     ILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEM
                     SMGVIFITHDMGVVAEIADRVLVMYQGEAVETGTVEQIFHAPQHPYTRALLAAVPQLG
                     AMKGLDYPRRFPLISLEHPAKQAPPIEQKTVVDGEPVLRVRNLVTRFPLRSGLLNRVT
                     REVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLS
                     PGKLQALRRDIQFIFQDPYASLDPRQTIGDSIIEPLRVHGLLPGKEAAARVAWLLERV
                     GLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLD
                     LQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPYTRKLLAA
                     VPVAEPSRQRPQRVLLSDDLPSNIHLRGEEVAAVSLQCVGPGHYVAQPQSEYAFMRR"
     gene            11865..13403
                     /gene="gsiB"
                     /locus_tag="RHX21_000108"
     CDS             11865..13403
                     /gene="gsiB"
                     /locus_tag="RHX21_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter substrate-binding
                     protein GsiB"
                     /protein_id="HDV1985355.1"
                     /translation="MARAVHRSGLVALGIATALMASCAFAAKDVVVAVGSNFTTLDPY
                     DANDTLSQAVAKSFYQGLFGLDKEMKLKNVLAESYTVSDDGITYTVKLREGIKFQDGT
                     DFNAAAVKANLDRASDPANHLKRYNLYKNIAKTEAIDPTTVKITLKQPFSAFINILAH
                     PATAMISPAALEKYGKEIGFHPVGTGPYELDTWNQTDFVKVKKFAGYWQPGLPKLDSI
                     TWRPVADNNTRAAMLQTGEAQFAFPIPYEQATLLEKNKNIELMASPSIMQRYISMNVT
                     QKPFDNPKVREALNYAINRPALVKVAFAGYATPATGVVPPSIAYAQSYKPWPYDPVKA
                     RELLKEAGYPNGFSTTLWSSHNHSTAQKVLQFTQQQLAQVGIKAQVTAMDAGQRAAEV
                     EGKGQKESGVRMFYTGWSASTGEADWALSPLFASQNWPPTLFNTAFYSNKQVDDFLAQ
                     ALKTNDPAEKTRLYKAAQDIIWQESPWIPLVVEKLVSAHSKNLTGFWIMPDTGFSFED
                     ADLQ"
     gene            13421..14341
                     /gene="gsiC"
                     /locus_tag="RHX21_000109"
     CDS             13421..14341
                     /gene="gsiC"
                     /locus_tag="RHX21_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter permease GsiC"
                     /protein_id="HDV1985356.1"
                     /translation="MLNYVIKRLLGLIPTLFIVSVLVFLFVHMLPGDPARLIAGPEAD
                     AQVIELVRQQLGLDQPLYHQFWHYISNAVQGDFGLSMVSRRPVADEIASRFMPTLWLT
                     ITSMVWAVIFGMAAGIIAAVWRNRWPDRLSMTIAVSGISFPAFALGMLLIQVFSVELG
                     WLPTVGADSWQHYILPSLTLGAAVAAVMARFTRASFVDVLSEDYMRTARAKGVSETWV
                     VLKHGLRNAMIPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQA
                     EILLFSLEFILINLVVDVLYAAINPAIRYK"
     gene            14344..15255
                     /gene="gsiD"
                     /locus_tag="RHX21_000110"
     CDS             14344..15255
                     /gene="gsiD"
                     /locus_tag="RHX21_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter permease GsiD"
                     /protein_id="HDV1985357.1"
                     /translation="MRLFNWRRQAVLNAMPLVKPDQVRTPWHEFWRRFRRQHMAMTAA
                     LFVILLIVVAIFARWIAPYDAENYFDYDNLNNGPSLQHWFGVDSLGRDIFSRVLVGAQ
                     ISLAAGVFAVFIGAAIGTLLGLLAGYYEGWWDRLIMRICDVLFAFPGILLAIAVVAVL
                     GSGIANVIIAVAIFSIPAFARLVRGNTLVLKQQTFIESARSIGASDMTILLRHILPGT
                     VSSIVVFFTMRIGTSIISAASLSFLGLGAQPPTPEWGAMLNEARADMVIAPHVAVFPA
                     LAIFLTVLAFNLLGDGLRDALDPKIKG"
     gene            15433..17781
                     /locus_tag="RHX21_000111"
     CDS             15433..17781
                     /locus_tag="RHX21_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDV1985358.1"
                     /translation="MLSLYEKIKIRLIILFLLAALSFIGLFFIINYQLVSERAVKRAD
                     SRFELIQKNVGYFFKDIERSALTLKDSLYLLKNTEEIQRAVILKMEMMPFLDSVGLVL
                     DDNKYYLFSRRANDKIVVYHQEQVNGPLVDESGRVIFADFNPSKRPWSVASDDSNNSW
                     NPAYNCFDRPGKKCISFTLRINGKDHDLLAVDKIHVDLNWRYLNEYLDQISANDEVLF
                     LKQGHEIIAKNQLAREKLIIYNSEGNYNIIDSVDTEYIAKTSAVPNNALFEIYFYYPG
                     GNLLNASDKLFYLPFAFIIIVLLVVYFMTTRVFRRQFSEMTELVNTLAFLPDSTDQIE
                     ALKIREGDAKEIISIKNSIAEMKDAEIERSNKLLSLISYDQESGFIKNMAIIESNNNQ
                     YLAVGIIKLCGLEAVEAVFGVDERNKIVRKLCQRIAEKYAQCCDIVTFNADLYLLLCR
                     ENVQTFTRKIAMVNDFDSSFGYRNLRIHKSAICEPLQGENAWSYAEKLKLAISSIRDH
                     MFSEFIFCDDAKLNEIEENIWIARNIRHAMEIGELFLVYQPIVDINTRAILGAEALCR
                     WVSAERGIISPLKFITIAEDIGFINELGYQIIKTAMGEFRHFSQRASLKDDFLLHINV
                     SPWQLNEPHFHERFTTIMKETGLKANSLCVEITETVIERINEHFYLNIEQLRKQGVRI
                     SIDDFGTGLSNLKRFYEINPDSIKVDSQFTGDIFGTAGKIVRIIFDLARYNRIPVIAE
                     GVESEDVARELIKLGCVQAQGYLYQKPMPFSAWDKSGKLVKE"
     gene            17789..19117
                     /locus_tag="RHX21_000112"
     CDS             17789..19117
                     /locus_tag="RHX21_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDV1985359.1"
                     /translation="MSRINKFVLTVSLLIFIMISAVACGIYTQMVKERVYSLKQSVID
                     TAFAVANIAEYRRSVAIDLINTLNPTEEQLLVGLRTAYADSVSPSYLYDVGPYLISSD
                     ECIQVKEFEKNYCADIMQVVKYRHVKNTGFISFDGKTFVYYLYPVTHNRSLIFLLGLE
                     RFSLLSKSLAMDSENLMFSLFKNGKPVTGDEYNAKNAIFTVSEAMEHFAYLPTGLYVF
                     AYKKDVYLRVCTLIIFFAALVAVISGTSCLYLVRRVINRGIVEKEAIINNHFERVLDG
                     GLFFSAADVKKLYSMYNSAFLDDLTKAMGRKSFDEDLKALPEKGGYLCLFDVDKFKNI
                     NDTFGHLLGDEVLMKVVKILKSQIPVDKGKIYRFGGDEFAVIYTGGTLEELLSILKEI
                     VHFQVGSINLSTSIGVAHSNECTTVERLKMLADERLYKSKKNGRAQISWQ"
     gene            complement(19164..20489)
                     /gene="rimO"
                     /locus_tag="RHX21_000113"
     CDS             complement(19164..20489)
                     /gene="rimO"
                     /locus_tag="RHX21_000113"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HDV1985360.1"
                     /translation="MSKVTPQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPSYDD
                     ADMVIVNTCGFIDSAVQESLEAIGEALNENGKVIVTGCLGAKEDQIREVHPKVLEITG
                     PHSYEQVLEHVHHYVPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIP
                     SMRGDLVSRPIGEVLSEAKRLVDAGVKEILVISQDTSAYGVDVKHRTGFHNGEPVKTS
                     MVSLCEQLSKLGIWTRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMK
                     RPGSVDRQLARIKQWREICPELTLRSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCF
                     KYSPVEGADANALPDQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVIIDEVDE
                     EGAIGRSMADAPEIDGAVYLNGETNVKPGDILRVKVEHADEYDLWGSRV"
     gene            20702..21085
                     /gene="bssR"
                     /locus_tag="RHX21_000114"
     CDS             20702..21085
                     /gene="bssR"
                     /locus_tag="RHX21_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator BssR"
                     /protein_id="HDV1985361.1"
                     /translation="MFVDRQRIDLLNRLIDARVDLAAYVQLRKAKGYMSVSESNHLRD
                     NFFKLNRELHDKSLRLNLHLDQEEWSALHHAEEALATAAVCLMSGHHDCPTVITVNAD
                     KLENCLMSLTLSIQSLQKHAMLEKA"
     gene            21196..22311
                     /gene="yliI"
                     /locus_tag="RHX21_000115"
     CDS             21196..22311
                     /gene="yliI"
                     /locus_tag="RHX21_000115"
                     /EC_number="1.1.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose sugar dehydrogenase YliI"
                     /protein_id="HDV1985362.1"
                     /translation="MHRQSFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLP
                     DNHGMLITLRGGELRHWQAGKGLSAPLSGVPDVWAHGQGGLLDVVLAPDFAQSRRIWL
                     SYSEVGDDGKAGTAVGYGRLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRLVFDGKGYL
                     FIALGENNQRPTAQDLDKLQGKLVRLTDQGEIPDDNPFIKESGVRAEIWSYGIRNPQG
                     MAMNPWSNALWLNEHGPRGGDEINIPQKGKNYGWPLATWGINYSGFKIPEAKGEIVAG
                     TEQPVFYWKDSPAVSGMAFYNSDKFPQWQQKLFIGALKDKDVIVMSVNGDKVTEDGRI
                     LTDRGQRIRDVRTGPDGYLYVLTDESSGELLKVSPRN"
     gene            complement(22308..22934)
                     /gene="gstB"
                     /locus_tag="RHX21_000116"
     CDS             complement(22308..22934)
                     /gene="gstB"
                     /locus_tag="RHX21_000116"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308945.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase GstB"
                     /protein_id="HDV1985363.1"
                     /translation="MITLWGRNNSTNVKKVLLTLEELELPYEQILAGREFGINHDADF
                     LAMNPNGLVPLLRDDESDLILWESNAIVRYLAAQYGQKRLWIDSPARRAEAEKWMDWA
                     NQTLSNAHRGILMGLVRTPPEERDQAAIDASCKECDALFALLDAELAKVKWFSGDEFG
                     VGDIAIAPFIYNLFNVGLTWTPRPNLQRWYQQLTERPAVRKVVMIPVS"
     gene            23180..24382
                     /gene="dacC"
                     /locus_tag="RHX21_000117"
     CDS             23180..24382
                     /gene="dacC"
                     /locus_tag="RHX21_000117"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase"
                     /protein_id="HDV1985364.1"
                     /translation="MTQYSSLLRGLAAGSAFLFLFAPTAFAAEQTVEAPSVDARAWIL
                     MDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQALKADKIKLTDMVTVGKDAWATGN
                     PALRGSSVMFLKPGDQVSVADLNKGVIIQSGNDACIALADYVAGSQESFIGLMNGYAK
                     KLGLTNTTFQTVHGLDAPGQFSTARDMALLGKALIHDVPEEYAIHKEKEFTFNKIRQP
                     NRNRLLWSSNLNVDGMKTGTTAGAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEK
                     LLTWGFRFFETVTPIKPDATFVTQRVWFGDKSEVNLGAGEAGSVTIPRGQLKNLKASY
                     TLTEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLIVMENVEEGGFFGRMWDFVMMKFH
                     QWFGNWFS"
     gene            complement(24429..25187)
                     /gene="deoR"
                     /locus_tag="RHX21_000118"
     CDS             complement(24429..25187)
                     /gene="deoR"
                     /locus_tag="RHX21_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor DeoR"
                     /protein_id="HDV1985365.1"
                     /translation="METRREERIGQLLQELKRSDKLHLKDAAALLGVSEMTIRRDLNN
                     HSAPVVLLGGYIVLEPRSASHYLLSDQKSRLVEEKRRAAKMAATLVEPDQTLFFDCGT
                     TTPWIIEAIDNEIPFTAVCYSLNTFLALKEKPHCRAFLCGGEFHASNAIFKPIDFQQT
                     LNNFCPDIAFYSAAGVHVSKGATCFNLEELPVKHWAMSMAQKHVLVVDHSKFGKVRPA
                     RMGDLKRFDIVVSDCCPEDEYVKYAQTHRIKLMY"
     gene            complement(25245..25841)
                     /gene="ybjG"
                     /locus_tag="RHX21_000119"
     CDS             complement(25245..25841)
                     /gene="ybjG"
                     /locus_tag="RHX21_000119"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDV1985366.1"
                     /translation="MLENLNLSLFSLINATPDSAPWMISLAIFIAKDLITVVPLLAAV
                     LWLWGLTAQRQLVIKIAIALAVSLFVSWTMGHLFPHDRPFVENIGYNFLHHAADDSFP
                     SDHGTVIFTFALAFLCWHRLWSGSLLMVLAVVIAWSRVYLGVHWPLDMLGGLLAGMIG
                     CLSAQIIWQAMGHKLYQRLQSWYRFCFALPIRKGWVRD"
     gene            26126..27358
                     /gene="mdfA"
                     /locus_tag="RHX21_000120"
     CDS             26126..27358
                     /gene="mdfA"
                     /locus_tag="RHX21_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdfA"
                     /protein_id="HDV1985367.1"
                     /translation="MQNKLASGARLGRQALLFPLCLVLYEFSTYIGNDMIQPGMLAVV
                     EQYQAGIDWVPTSMTAYLAGGMFLQWLLGPLSDRIGRRPVMLAGVVWFIITCLAILLA
                     QNIEQFTLLRFLQGISLCFIGAVGYAAIQESFEEAVCIKITALMANVALIAPLLGPLV
                     GAAWIHVLPWEGMFVLFAALAAISFFGLQQAMPETATRIGEKLSLKELGRDYKLVLKN
                     GRFVAGALALGFVSLPLLAWIAQSPIIIITGEQLSSYEYGLLQVPIFGALIAGNLLLA
                     RLTSRRTVRSLIIMGGWPIIIGLLVAAAATVISSHAYLWMTAGLSIYAFGIGLANAGL
                     VRLTLFASDMSKGTVSAAMGMLQMLIFTVGIEISKHAWLNGGNGLFNLFNLVNGILWL
                     SLMVIFLKDKQMGNSHEG"
     gene            complement(27399..27683)
                     /locus_tag="RHX21_000121"
     CDS             complement(27399..27683)
                     /locus_tag="RHX21_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1985368.1"
                     /translation="MFMKNCLLLGALLMGFTGVAMAQSVTVDVPSGYKVVVVPDSVSV
                     PQAVSVATVPQTVYVAPAPAPAYRPHPYVRHLASVGEGMVIEHQIDDHHH"
     gene            complement(27769..28584)
                     /gene="ybjI"
                     /locus_tag="RHX21_000122"
     CDS             complement(27769..28584)
                     /gene="ybjI"
                     /locus_tag="RHX21_000122"
                     /EC_number="3.1.3.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308951.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-amino-6-(5-phospho-D-ribitylamino)uracil
                     phosphatase"
                     /protein_id="HDV1985369.1"
                     /translation="MSIKLIAVDMDGTFLSDQKTYNRERFMAQYQQMKAQGIRFVVAS
                     GNQYYQLISFFPEIANEIAFVAENGGWVVSEGKDVFNGELSKDAFTTVVEHLLTRPEV
                     EIIACGKNSAYTLKKYDDAMKTVAEMYYHRLEYVDNFDNLEDIFFKFGLNLSDELIPQ
                     VQKALHEAIGDIMVPVHTGNGSIDLIIPGVHKANGLRQLQKLWGIDDSEVVVFGDGGN
                     DIEMLRQAGFSFAMENAGNAVVAAAKYRAGSNNREGVLDVIDKVLKHEAPFDQ"
     gene            complement(28584..29792)
                     /locus_tag="RHX21_000123"
     CDS             complement(28584..29792)
                     /locus_tag="RHX21_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1985370.1"
                     /translation="MTVNSSRNALKRRTWALFMFFFLPGLLMASWATRTPAIRDILSV
                     SIAEMGGVLFGLSIGSMSGILCSAWLVKRFGTRNVILVTMSCALIGMMILSLALWLTS
                     PLLFAVGLGVFGASFGSAEVAINVEGAAVEREMNKTVLPMMHGFYSLGTLAGAGVGMA
                     LTAFGVPATVHILLAALVGIAPIYIAIQAIPDGTGKNAADGTQHGEKGIPFYRDIQLL
                     LIGVVVLAMAFAEGSANDWLPLLMVDGHGFSPTSGSLIYAGFTLGMTVGRFTGGWFID
                     RYSRVAVVRASALMGALGIGLIIFVDSAWVAGVSVVLWGLGASLGFPLTISAASDTGP
                     DAPTRVSVVATTGYLAFLVGPPLLGYLGEHYGLRSAMLVVLALVILAAIVAKAVAKPD
                     TKTQTAMENS"
     gene            29876..30412
                     /gene="rcdA"
                     /locus_tag="RHX21_000124"
     CDS             29876..30412
                     /gene="rcdA"
                     /locus_tag="RHX21_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator RcdA"
                     /protein_id="HDV1985371.1"
                     /translation="MRRANDPQRREKIIQATLEAVKLYGIHAVTHRKIATLAGVPLGS
                     MTYYFSGIDELLLEAFSSFTEIMSRQYQAFFSDVSDAQGACQAITDMIYSSQVATPDN
                     MELMYQLYALASRKPLLKTVMQNWMQRSQQTLEQWFEPGTARALDAFIEGMTLHFVTD
                     RKPLSREEILRMVERVAG"
     gene            complement(30587..32272)
                     /locus_tag="RHX21_000125"
     CDS             complement(30587..32272)
                     /locus_tag="RHX21_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate:alanine antiporter"
                     /protein_id="HDV1985372.1"
                     /translation="MNINVAELLNGNYILLLFVVLALGLCLGKLRLGSIQLGNSIGVL
                     VVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGS
                     ALVIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHFGMESRQLSLALDNLS
                     LGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAY
                     RVGPELVAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYP
                     DAHARLDPSFRNGKEVFDRDLLDMRIVTEEVVVKNHNAVGKRLAQLKLTDHGCFLNRV
                     IRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFVI
                     GLMIGMITFQFSTFSFGMGNAAGLLFAGIMLGFMRANHPTFGYIPQGALSMVKEFGLM
                     VFMAGVGLSAGSGINNGLGAIGGQMLIAGLIVSLVPVVICFLFGAYVLRMNRALLFGA
                     MMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTIIVMVWPGLG"
     gene            32542..32919
                     /locus_tag="RHX21_000126"
     CDS             32542..32919
                     /locus_tag="RHX21_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YbjM"
                     /protein_id="HDV1985373.1"
                     /translation="MKHKQRWAGAICCFVLFIVVCLFLATHMKGAFRAAGHPEIGLLF
                     FILPGAVASFFSQRREVLKPLFGAMLAAPCSMLIMRLFFSPTRSFWQELAWLLSAVFW
                     CALGALCFLFISSLFKPQHRKNQ"
     gene            complement(32949..33206)
                     /gene="grxA"
                     /locus_tag="RHX21_000127"
     CDS             complement(32949..33206)
                     /gene="grxA"
                     /locus_tag="RHX21_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 1"
                     /protein_id="HDV1985374.1"
                     /translation="MQTVIFGRSGCPYCVRAKDLAEKLSNERDDFQYQYVDIRAEGIT
                     KEDLQQKAGKPVETVPQIFVDQQHIGGYTDFAAWVKENLDA"
     gene            33366..33653
                     /locus_tag="RHX21_000128"
     CDS             33366..33653
                     /locus_tag="RHX21_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1418 family protein"
                     /protein_id="HDV1985375.1"
                     /translation="MRAIGKLPKGVLILEFIGMMLLAVALLSVSDSLSLPEPFSRPEV
                     QILMIFLGVLLMLPAAVVVILQVAKRLAPQLMNRPPQYSRSEREKDNDANH"
     gene            33637..34359
                     /gene="nfsA"
                     /locus_tag="RHX21_000129"
     CDS             33637..34359
                     /gene="nfsA"
                     /locus_tag="RHX21_000129"
                     /EC_number="1.5.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase NfsA"
                     /protein_id="HDV1985376.1"
                     /translation="MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQ
                     CSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFCADFNRHLQICPDAQLGLAEQLL
                     LGVVDTAMMAQNALIAAESLGLGGVYIGGLRNNIEAVTKLLKLPQHVLPLFGLCLGWP
                     ADNPDLKPRLPASILVHENSYQPLDKGALAQYDEQLAEYYLTRGSNNRRDTWSDHIRR
                     TIIKESRPFILDYLHKQGWATR"
     gene            34420..35322
                     /gene="rimK"
                     /locus_tag="RHX21_000130"
     CDS             34420..35322
                     /gene="rimK"
                     /locus_tag="RHX21_000130"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6--L-glutamate ligase"
                     /protein_id="HDV1985377.1"
                     /translation="MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPA
                     ASSIHYKGRKLPHFDAVIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDKLR
                     SMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQGIGVVLAETRQAA
                     ESVIDAFRGLNAHILVQEYIKEAQGCDIRCLVVGDEVVAAIERRAKEGDFRSNLHRGG
                     AASVASITPQEREIAIKAARTMALDVAGVDILRANRGPLVMEVNASPGLEGIEKTTGI
                     DIAGKMIRWIERHATTEYCLKTGG"
     gene            35410..35886
                     /locus_tag="RHX21_000131"
     CDS             35410..35886
                     /locus_tag="RHX21_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjN domain-containing protein"
                     /protein_id="HDV1985378.1"
                     /translation="MTSLVVPGLDTLRQWLDDLGMSFFECDNCQALHLPHMQNFDGVF
                     DAKIDLIDNTILFSAMAEVRPSAVLPLAADLSAINASSLTVKAFLDMQDDNLPKLVVC
                     QSLSVMQGVTYEQFAWFVRQSEEQISMVILEANAHQLLLPTDDEGQNNVTENYFLH"
     gene            36238..37350
                     /gene="potF"
                     /locus_tag="RHX21_000132"
     CDS             36238..37350
                     /gene="potF"
                     /locus_tag="RHX21_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein PotF"
                     /protein_id="HDV1985379.1"
                     /translation="MTALNKKWLSGLVAGALMAVSVGTLAAEQKTLHIYNWSDYIAPD
                     TVANFEKETGIKVVYDVFDSNEVLEGKLMAGSTGFDLVVPSASFLERQLTAGVFQPLD
                     KSKLPEWKNLDPELLKLVAKHDPDNKFAMPYMWATTGIGYNVDKVKAVLGENAPVDSW
                     DLILKPENLEKLKSCGVSFLDAPEEVFATVLNYLGKDPNSTKADDYTGPATDLLLKLR
                     PNIRYFHSSQYINDLANGDICVAIGWAGDVWQASNRAKEAKNGVNVSFSIPKEGAMAF
                     FDVFAMPADAKNKDEAYQFLNYLLRPDVVAHISDHVFYANANKAATPLVSAEVRENPG
                     IYPPADVRAKLFTLKVQDPKIDRVRTRAWTKVKSGK"
     gene            37445..38578
                     /gene="potG"
                     /locus_tag="RHX21_000133"
     CDS             37445..38578
                     /gene="potG"
                     /locus_tag="RHX21_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter ATP-binding subunit
                     PotG"
                     /protein_id="HDV1985380.1"
                     /translation="MNDAIPRPQAKTRKALTPLLEIRNLTKSYDGQHAVDDVSLTIYK
                     GEIFALLGASGCGKSTLLRMLAGFEQPSAGQIMLDGVDLSQVPPYLRPINMMFQSYAL
                     FPHMTVEQNIAFGLKQDKLPKAEIVSRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVAL
                     ARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAG
                     RIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIGSVNVFEGVLKERHEDGLVLYSPGLV
                     HPLKVDVDASVVDNVPVHVALRPEKIMLCEEPPADGFNFAVGEVMHIAYLGDLSVYHV
                     RLKSGQMISAQLQNAHRYRKGLPTWGDEVRLCWEVDSCVVLTV"
     gene            38588..39541
                     /gene="potH"
                     /locus_tag="RHX21_000134"
     CDS             38588..39541
                     /gene="potH"
                     /locus_tag="RHX21_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter permease PotH"
                     /protein_id="HDV1985381.1"
                     /translation="MSTLEPAAQSKPPGGFKLWLSQLQMKHGRKLVIALPYIWLILLF
                     LLPFLIVFKISLAEMARAIPPYTELMEWADGQLSITLNLGNFLQLTDDPLYFDAYLQS
                     LQVAAISTFCCLLIGYPLAWAVAHSKPSTRNILLLLVILPSWTSFLIRVYAWMGILKN
                     NGVLNNFLLWLGVIDQPLTILHTNLAVYIGIVYAYVPFMVLPIYTALIRIDYSLVEAA
                     LDLGARPLKTFFTVIVPLTKGGIIAGSMLVFIPAVGEFVIPELLGGPDSIMIGRVLWQ
                     EFFNNRDWPVASAVAIIMLLLLIVPIMWFHKHQQKSVGEHG"
     gene            39538..40383
                     /gene="potI"
                     /locus_tag="RHX21_000135"
     CDS             39538..40383
                     /gene="potI"
                     /locus_tag="RHX21_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter permease PotI"
                     /protein_id="HDV1985382.1"
                     /translation="MNNLPVVRSPWRIVILLLGFTFLYAPMLMLVIYSFNSSKLVTVW
                     AGWSTRWYGELLRDDAMMSAVGLSLTIAACAATAAAILGTIAAVVLVRFGRFRGSNGF
                     AFMITAPLVMPDVITGLSLLLLFVALAHAIGWPADRGMLTIWLAHVTFCTAYVAVVIS
                     SRLRELDRSIEEAAMDLGATPLKVFFVITLPMIMPAIISGWLLAFTLSLDDLVIASFV
                     SGPGATTLPMLVFSSVRMGVNPEINALATLILGAVGIVGFIAWYLMARAEKQRIRDIQ
                     RARHG"
     gene            40443..40931
                     /locus_tag="RHX21_000136"
     CDS             40443..40931
                     /locus_tag="RHX21_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjO family protein"
                     /protein_id="HDV1985383.1"
                     /translation="MEDETLGFFKKTSSSHARLNVPALVQVAALAIIMIRGLDVLMIF
                     NTLGVRGIGEFIHRSVQTWSLTLVFLSSLVLVFIEIWCAFSLVKGRRWARWLYLLTQI
                     TAASYLWAASLGYGYPELFSIPGESKREIFHSLMLQKLPDMLILMLLFVPSTSRRFFQ
                     LQ"
     gene            40972..42099
                     /gene="rlmC"
                     /locus_tag="RHX21_000137"
     CDS             40972..42099
                     /gene="rlmC"
                     /locus_tag="RHX21_000137"
                     /EC_number="2.1.1.189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(747)-C(5))-methyltransferase
                     RlmC"
                     /protein_id="HDV1985384.1"
                     /translation="MQCALYDAGRCRSCQWITQPIPEQLSAKTADLKNLLADFPVEEW
                     CAPVSGPEQGFRNKAKMVVSGSVEKPLLGMLHRDGTPEDLCDCPLYPASFAPVFAALK
                     PFIARAGLTPYNVARKRGELKYILLTESQSDGGMMLRFVLRSETKLAQLRKALPWLQE
                     QLPQLKVITVNIQPVHMAIMEGETEIYLTEQQALAERFNDVPLWIRPQSFFQTNPAVA
                     SQLYATARDWVRQLPVKHMWDLFCGVGGFGLHCATPDMQLTGIEIASEAIACAKQSAA
                     ELGLTRLQFQALDSTQFATAQGEVPELVLVNPPRRGIGKPLCDYLSTMAPRFIIYSSC
                     NAQTMAKDIRELPGYRIERVQLFDMFPHTAHYEVMTLLVKQ"
     gene            complement(42274..43005)
                     /gene="artJ"
                     /locus_tag="RHX21_000138"
     CDS             complement(42274..43005)
                     /gene="artJ"
                     /locus_tag="RHX21_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein ArtJ"
                     /protein_id="HDV1985385.1"
                     /translation="MKKLVLAALLASFTFGASAAEKINFGVSATYPPFESIGANNEIV
                     GFDIDLAKALCKQMQAECTFTNHAFDSLIPSLKFRKYDAVISGMDITPERSKQVSFTT
                     PYYENSAVVIAKKDTYKTFADLKGKRIGMENGTTHQKYIQDQHPEVKTVSYDSYQNAF
                     IDLKNGRIDGVFGDTAVVNEWLKTNPQLGVATEKVTDPQYFGTGLGIAVRPDNKALLE
                     KLNNALAAIKADGTYQKINDQWFPQ"
     gene            complement(43297..43965)
                     /gene="artM"
                     /locus_tag="RHX21_000139"
     CDS             complement(43297..43965)
                     /gene="artM"
                     /locus_tag="RHX21_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter permease ArtM"
                     /protein_id="HDV1985386.1"
                     /translation="MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVL
                     VWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEYPALWHLLSEPWLCALIALSLNS
                     AAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFK
                     STSLAYTITLMEVMGYSQLLYGRTYDVMVFGAAGIIYLVVNGLLTLMMRLIERKALAF
                     ERRN"
     gene            complement(43965..44681)
                     /gene="artQ"
                     /locus_tag="RHX21_000140"
     CDS             complement(43965..44681)
                     /gene="artQ"
                     /locus_tag="RHX21_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter permease ArtQ"
                     /protein_id="HDV1985387.1"
                     /translation="MNEFFPLASAAGMTVGLAVCALIVGLALAMFFAVWESAKWRPVA
                     WAGSALVTILRGLPEILVVLFIYFGSSQLLLTLSDGFTINLGFVQIPVQMDIENFDVS
                     PFLCGVIALSLLYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRH
                     ALPGLGNQWLVLLKDTALVSLISVNDLMLQTKSIATRTQEPFTWYIVAAAIYLVITLL
                     SQYILKRIDLRATRFERRPS"
     gene            complement(44688..45419)
                     /gene="artJ"
                     /locus_tag="RHX21_000141"
     CDS             complement(44688..45419)
                     /gene="artJ"
                     /locus_tag="RHX21_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter substrate-binding
                     protein"
                     /protein_id="HDV1985388.1"
                     /translation="MKKVLIAALIAGFSLSATAAETIRFATEASYPPFESIDANNQIV
                     GFDVDLAQALCKEIDATCTFSNQAFDSLIPSLKFRRVEAVMAGMDITPEREKQVLFTT
                     PYYDNSALFVGQQGKYTSVDQMKGKKVGVQNGTTHQKFIMDKHPEITTVPYDSYQNAK
                     LDLQNGRIDGVFGDTAVVTEWLKDNPKLAAVGDKVTDKDYFGTGLGIAVRQGNTELQQ
                     KLNTALEKVKKDGTYETIYNKWFQK"
     gene            complement(45437..46165)
                     /gene="artP"
                     /locus_tag="RHX21_000142"
     CDS             complement(45437..46165)
                     /gene="artP"
                     /locus_tag="RHX21_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter ATP-binding protein
                     ArtP"
                     /protein_id="HDV1985389.1"
                     /translation="MSIQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSL
                     LRVLNLLEMPRSGTLNIAGNHFDFTKTPSDKAIRDLRRNVGMVFQQYNLWPHLTVQQN
                     LIEAPCRVLGLSKDQALARAEKLLERLRLKPYSDRYPLHLSGGQQQRVAIARALMMEP
                     QVLLFDEPTAALDPEITAQIVSIIRELAETNITQVIVTHEVEVARKTASRVVYMENGH
                     IVEQGDASCFTEPQTEAFKNYLSH"
     gene            complement(46383..46898)
                     /locus_tag="RHX21_000143"
     CDS             complement(46383..46898)
                     /locus_tag="RHX21_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDV1985390.1"
                     /translation="MRYSKLTMLIPCALLLSACTTVTPAYKDNGTRSGPCVEGGPDNV
                     AQQFYDYRILHRSNDITALRPYLSDKLATLLSDASRDNNHRELLTNDPFSSRTTLPES
                     ARVASASTIPNRDARNIPLRVDLKQGDQSWQDEVLMIQEGQCWVIDDVRYLGGSVHAT
                     AGTLRQSIENR"
     gene            47024..47347
                     /locus_tag="RHX21_000144"
     CDS             47024..47347
                     /locus_tag="RHX21_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HDV1985391.1"
                     /translation="MQFSTTPTLEGQTIVEYCGVVTGEAILGANIFRDFFAGIRDIVG
                     GRSGAYEKELRKAREIAFEELGSQARALGADAVVGIDIDYETVGQNGSMLMVSVSGTA
                     VKTRR"
     gene            47344..48174
                     /gene="amiD"
                     /locus_tag="RHX21_000145"
     CDS             47344..48174
                     /gene="amiD"
                     /locus_tag="RHX21_000145"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiD"
                     /protein_id="HDV1985392.1"
                     /translation="MRRVFWLIAAALLLAGCAGEKGIVEKEGYQLDTRRQAQAAYPRI
                     KVLVIHYTADDFDSSLATLTDKQVSSHYLVPAVPPRYNGKPRIWQLVPEQELAWHAGI
                     SAWRGATRLNDTSIGIELENRGWQKSAGVKYFAPFEPAQIQALIPLAKDIIARYHIKP
                     ENVVAHADIAPQRKDDPGPLFPWQQLAQQGIGAWPDAQRVNFYLAGRAPHTPVDTASL
                     LELLARYGYDVKPDMTPREQRRVIMAFQMHFRPTLYNGEADAETQAIAEALLEKYGQD
                     "
     gene            complement(48171..49184)
                     /locus_tag="RHX21_000146"
     CDS             complement(48171..49184)
                     /locus_tag="RHX21_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415389.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDV1985393.1"
                     /translation="MKVLVTGATSGLGRNAVEFLCQKGISVRATGRNEAMGKLLEKMG
                     AEFVPADLTELVSSQAKVMLAGIDTLWHCSSFTSPWGTQQAFDLANVRATRRLGEWAV
                     AWGVRNFIHISSPSLYFDYHHHRDIKEDFRPHRFANEFARSKAASEEVINMLSQANPQ
                     TRFTILRPQSLFGPHDKVFIPRLAHMMHHYGSILLPHGGSALVDMTYYENAVHAMWLA
                     SQEACDKLPSGRVYNITNGEHRTLRSIVQKLIDELNIDCRIRSVPYPMLDMIARSMER
                     LGRKSAKEPPLTHYGVSKLNFDFTLDITRAQEELGYQPVITLDEGIEKTAAWLRDHGK
                     LPR"
     gene            complement(49283..50713)
                     /locus_tag="RHX21_000147"
     CDS             complement(49283..50713)
                     /locus_tag="RHX21_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415390.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2867 domain-containing protein"
                     /protein_id="HDV1985394.1"
                     /translation="MPQRILVLGASGYIGQHLVRTLSQQGHQILAAARHVDRLAKLQL
                     ANVSCHKVDLSWPDNLPALLQDIDTVYFLVHSMGEGGDFIAQERQVALNVRDALREVP
                     VKQLIFLSSLQAPPHEQSDHLRARQATADILREANVPVTELRAGIIVGAGSAAFEVMR
                     DMVYNLPVLTPPRWVRSRTTPIALENLLHYLVALLDHPASEHRIFEAAGPEVLSYQQQ
                     FEHFMAVSGKRRWLIPIPLPTRWISVWFLNVITSVPPTTARALIQGLKHDLLADDTAL
                     RALIPQRLIAFDDAVRSTLKEEEKLVNSSDWGYDAQAFARWRPEYGYFAKQAGFTVKT
                     SASLAALWQVVNQIGGKERYFFGNILWQTRALMDRAIGHKLAKGRPEREYLQTGDAVD
                     SWKVIVVEPEKQLTLLFGMKAPGLGRLCFSLEDKGDYRTIDVRAFWHPHGMPGLFYWL
                     LMIPAHLFIFRGMAKQIARLAEQSTD"
     gene            complement(50724..51725)
                     /gene="ltaE"
                     /locus_tag="RHX21_000148"
     CDS             complement(50724..51725)
                     /gene="ltaE"
                     /locus_tag="RHX21_000148"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HDV1985395.1"
                     /translation="MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAA
                     ELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQP
                     IDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRERN
                     LALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAI
                     RWRKMAGGGMRQSGILAAAGMYALKNNVARLQEDHDNAAWMAEQLREAGADVMRQDTN
                     MLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSREQLAEVAAHWRAFLAR"
     gene            complement(51762..53480)
                     /gene="poxB"
                     /locus_tag="RHX21_000149"
     CDS             complement(51762..53480)
                     /gene="poxB"
                     /locus_tag="RHX21_000149"
                     /EC_number="1.2.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone-dependent pyruvate dehydrogenase"
                     /protein_id="HDV1985396.1"
                     /translation="MKQTVAAYIAKTLESAGVKRIWGVTGDSLNGLSDSLNRMGTIEW
                     MSTRHEEVAAFAAGAEAQLSGELAVCAGSCGPGNLHLINGLFDCHRNHVPVLAIAAHI
                     PSSEIGSGYFQETHPQELFRECSHYCELVSSPEQIPQVLAIAMRKAVLNRGVSVVVLP
                     GDVALKPAPEGATTHWYHAPQPIVTPEEEELRKLAQLLRYSSNIALMCGSGCAGAHKE
                     LVEFAGKIKAPIVHALRGKEHVEYDNPYDVGMTGLIGFSSGFHTMMNADTLVLLGTQF
                     PYRAFYPTDAKIIQIDINPASIGAHSKVDMALVGDIKSTLRALLPLVEEKTDRKFLDK
                     ALEDYRDARKGLDDLAKPSEKAIHPQYLAQQISHFAADDAIFTCDVGTPTVWAARYLK
                     MNGKRRLLGSFNHGSMANAMPQALGAQATEPERQVVAMCGDGGFSMLMGDFLSVVQMK
                     LPVKIVVFNNSVLGFVAMEMKAGGYLTDGTELHDTNFARIAEACGITGIRVEKASEVD
                     EALQRAFSIDGPVLVDVVVAKEELAIPPQIKLEQAKGFSLYMLRAIISGRGDEVIELA
                     KTNWLR"
     gene            complement(53613..54581)
                     /gene="hcr"
                     /locus_tag="RHX21_000150"
     CDS             complement(53613..54581)
                     /gene="hcr"
                     /locus_tag="RHX21_000150"
                     /EC_number="1.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidoreductase"
                     /protein_id="HDV1985397.1"
                     /translation="MTMPTNQCPWRMQVHHITQETPDVWTISLICHDYYPYRAGQYAL
                     VSVRNSAETLRAYTISSTPGVSEYITLTVRRIDDGVGSQWLTRDVKRGDYLWLSDAMG
                     EFTCDDKAEDKFLLLAAGCGVTPIMSMRRWLAKNRPQADVRVIYNVRTPQDVIFADEW
                     RNYPVTLVAENNVTEGFIAGRLTRELLAGVPDLASRTVMTCGPAPYMDWVEQEVKALG
                     VTRFFKEKFFTPVAEAATSGLKFTKLQPAREFYAPVGTTLLEALESNNVPVVAACRAG
                     VCGCCKTKVVSGEYTVSSTMTLTDAEIAEGYVLACSCHPQGDLVLA"
     gene            complement(54593..56245)
                     /gene="hcp"
                     /locus_tag="RHX21_000151"
                     /gene_synonym="priS"
     CDS             complement(54593..56245)
                     /gene="hcp"
                     /locus_tag="RHX21_000151"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HDV1985398.1"
                     /translation="MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIAALQG
                     LSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQC
                     LAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLK
                     GAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSIL
                     DAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLP
                     AHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRS
                     IVGWPGVRHLDGEDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVS
                     REKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLP
                     RLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVK
                     NIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA"
     gene            complement(56389..57288)
                     /gene="lysO"
                     /locus_tag="RHX21_000152"
     CDS             complement(56389..57288)
                     /gene="lysO"
                     /locus_tag="RHX21_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415395.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lysine exporter LysO"
                     /protein_id="HDV1985399.1"
                     /translation="MFSGLLIILVPLIVGYLIPLRQQAALKVINQLLSWMVYLILFFM
                     GISLAFLDNLASNLLAILHYSAVSITVILLCNIAALMWLERGLPWRNHHQQEKLPSRI
                     AMALESLKLCGVVVIGFAIGLSGLAFLQHATEASEYTLILLLFLVGIQLRNNGMTLKQ
                     IVLNRRGMIVAVVVVVSSLIGGLINAFILDLPINTALAMASGFGWYSLSGILLTESFG
                     PVIGSAAFFNDLARELIAIMLIPGLIRRSRSTALGLCGATSMDFTLPVLQRTGGLDMV
                     PAAIVHGFILSLLVPILIAFFSA"
     gene            complement(57781..58476)
                     /gene="aqpZ"
                     /locus_tag="RHX21_000153"
     CDS             complement(57781..58476)
                     /gene="aqpZ"
                     /locus_tag="RHX21_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin Z"
                     /protein_id="HDV1985400.1"
                     /translation="MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFG
                     LTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLI
                     ASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGTTDKFAPAG
                     FAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGII
                     GGLIYRTLLEKRD"
     gene            58902..60560
                     /locus_tag="RHX21_000154"
     CDS             58902..60560
                     /locus_tag="RHX21_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent endonuclease"
                     /protein_id="HDV1985401.1"
                     /translation="MILERVEIVGFRGINRLSLMLEQNNVLIGENAWGKSSLLDALTL
                     LLSPESDLYHFERDDFWFPPGDINGREHHLHIILTFRESLPGRHRVRRYRPLEACWTP
                     CTDGYHRIFYRLEGESAEDGSVMTLRSFLDKDGHPIDVEDINDQARHLVRLMPVLRLR
                     DARFMRRIRNGTVPNVPNVEVTARQLDFLARELSSHPQNLSDGQIRQGLSAMVQLLEH
                     YFSEQGAGQARYRLMRRRASNEQRSWRYLDIINRMIDRPGGRSYRVILLGLFATLLQA
                     KGTLRLDKDARPLLLIEDPETRLHPIMLSVAWHLLNLLPLQRIATTNSGELLSLTPVE
                     HVCRLVRESSRVAAWRLGPSGLSTEDSRRISFHIRFNRPSSLFARCWLLVEGETETWV
                     INELARQCGHHFDAEGIKVIEFAQSGLKPLVKFARRMGIEWHVLVDGDEAGKKYAATV
                     RSLLNNDREAEREHLTALPALDMEHFMYRQGFSDVFHRVAQIPENVPMNLRKIISKAI
                     HRSSKPDLAIEVAMEAGRRGVDSVPTLLKKMFSRVLWLARGRAD"
     gene            complement(60557..61513)
                     /locus_tag="RHX21_000155"
     CDS             complement(60557..61513)
                     /locus_tag="RHX21_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001322270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirK/YbjX family protein"
                     /protein_id="HDV1985402.1"
                     /translation="MNMSQLTERTFTPSESLSSLSLFLSLARGQCRPGKFWHRRSFRQ
                     KFLLRSLIMPRLSVEWMNELSHWPNLNVLLTRQPRLPVRLHRPYLAANLSRKQLLEAL
                     RYHYALLRGCMSAEEFSLYLNTPGLQLAKLEGKNGEQFTLELTMMISMDKEGDSTILF
                     RNSEGIPLAEITFTLCEYQGKRTMFIGGLQGAKWEIPHQEIQNATKACHGLFPKRLVM
                     EAACLFAQRLQVEQIIAVSNETHIYRSLRYRDKEGKIHADYNAFWESVGGVCDAERHY
                     RLPAQIARKEIAEIASKKRAEYRRRYEMLDAIQPQMATMFRG"
     gene            61664..62779
                     /gene="macA"
                     /locus_tag="RHX21_000156"
     CDS             61664..62779
                     /gene="macA"
                     /locus_tag="RHX21_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308991.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide transporter subunit MacA"
                     /protein_id="HDV1985403.1"
                     /translation="MKKRKTVKKRYVIALVIVIAGLITLWRILNAPVPTYQTLIVRPG
                     DLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAENQIK
                     EVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTQAVSQQDLDTAATEMAVKQAQI
                     GTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLA
                     DMSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKVNDAIFYY
                     ARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETR
                     EREVTIGARNDTDVEIVKGLEAGDEVVIGEAKPGAAQ"
     gene            62776..64722
                     /gene="macB"
                     /locus_tag="RHX21_000157"
     CDS             62776..64722
                     /gene="macB"
                     /locus_tag="RHX21_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide ABC transporter ATP-binding
                     protein/permease MacB"
                     /protein_id="HDV1985404.1"
                     /translation="MTPLLELKDIRRSYPAGDEQVEVLKGITLDIYAGEMVAIVGASG
                     SGKSTLMNILGCLDKATSGTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLT
                     AEQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRTEYYPAQLSGGQQQRVSIARALM
                     NGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRD
                     GEIVRNPPAIEKVNVAGGTEPVVNTVSGWRQFVSGFNEALTMAWRALAANKMRTLLTM
                     LGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDVYPGKDFGDDDPQYQQALKYD
                     DLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQ
                     EQLNGRAQVVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVL
                     RVWLPYSTMSGRVMGQSWLNSITVRVKEGFDSAEAEQQLTRLLSLRHGKKDFFTWNMD
                     GVLKTVEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARAS
                     DVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTVT
                     GILFGWLPARNAARLDPVDALARE"
     gene            complement(64795..65019)
                     /gene="cspD"
                     /locus_tag="RHX21_000158"
     CDS             complement(64795..65019)
                     /gene="cspD"
                     /locus_tag="RHX21_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock-like protein CspD"
                     /protein_id="HDV1985405.1"
                     /translation="MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKA
                     GQSVQFDVHQGPKGNHASVIVPVEVEAAVA"
     gene            65342..65662
                     /gene="clpS"
                     /locus_tag="RHX21_000159"
     CDS             65342..65662
                     /gene="clpS"
                     /locus_tag="RHX21_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease adapter ClpS"
                     /protein_id="HDV1985406.1"
                     /translation="MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVI
                     DVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCT
                     LEKA"
     gene            65693..67969
                     /gene="clpA"
                     /locus_tag="RHX21_000160"
     CDS             65693..67969
                     /gene="clpA"
                     /locus_tag="RHX21_000160"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpA"
                     /protein_id="HDV1985407.1"
                     /translation="MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREAL
                     EACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRNE
                     VTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSE
                     EQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGV
                     GKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQ
                     DTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKD
                     RALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDR
                     HLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLK
                     NLGDRLKMLVFGQDKAIEALTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQL
                     SKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEI
                     EKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDN
                     STDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEV
                     SQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKN
                     ELTYGFQSAQKHKAEAAH"
     gene            complement(68314..68401)
                     /locus_tag="RHX21_000161"
     tRNA            complement(68314..68401)
                     /locus_tag="RHX21_000161"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(68365..68367),aa:Ser,seq:gga)
     gene            complement(68655..68873)
                     /gene="infA"
                     /locus_tag="RHX21_000162"
     CDS             complement(68655..68873)
                     /gene="infA"
                     /locus_tag="RHX21_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HDV1985408.1"
                     /translation="MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNY
                     IRILTGDKVTVELTPYDLSKGRIVFRSR"
     gene            complement(69158..69862)
                     /gene="aat"
                     /locus_tag="RHX21_000163"
     CDS             complement(69158..69862)
                     /gene="aat"
                     /locus_tag="RHX21_000163"
                     /EC_number="2.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl/phenylalanyl-tRNA--protein transferase"
                     /protein_id="HDV1985409.1"
                     /translation="MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQR
                     GIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGC
                     ASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFS
                     RMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGR
                     LPNNFWVPRCLFSPQE"
     gene            complement(69904..71625)
                     /gene="cydC"
                     /locus_tag="RHX21_000164"
     CDS             complement(69904..71625)
                     /gene="cydC"
                     /locus_tag="RHX21_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/glutathione ABC transporter ATP-binding
                     protein/permease CydC"
                     /protein_id="HDV1985410.1"
                     /translation="MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLS
                     ASAVAGVAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSK
                     LLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDF
                     TLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGA
                     SDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQP
                     GALIALFVFCALAAFEALAPVTGAFQHLGQVIASAVRITDLTDQKPEVTFPDTQTRVA
                     DRVSLTLRDVQFTYPEQSQQALKGISLQVNAGEHIAILGRTGCGKSTLLQLLTRAWDP
                     QQGEILLNDSPIASLNEAALRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALAESL
                     RRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDEPTEGLDAT
                     TESQILELLAEMMREKTVLMVTHRLRGLSRFQQIIVMDNGQIIEQGTHAELLARQGRY
                     YQFKQGL"
     gene            complement(71626..73392)
                     /gene="cydD"
                     /locus_tag="RHX21_000165"
     CDS             complement(71626..73392)
                     /gene="cydD"
                     /locus_tag="RHX21_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/glutathione ABC transporter
                     permease/ATP-binding protein CydD"
                     /protein_id="HDV1985411.1"
                     /translation="MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWF
                     MARILQHMIMENIPREALLLPFTLLVLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQV
                     LDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFP
                     SNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIF
                     GRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAVYFGFSYLGEL
                     DFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAH
                     PQRGEAELASTDPVTIEAEDLFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSL
                     LNALSGFLSYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDA
                     SEQELQAALDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARALLNPCSLLL
                     LDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGRIIEQGR
                     YAELSVAGGPFATLLAHRQEEI"
     gene            complement(73515..74480)
                     /gene="trxB"
                     /locus_tag="RHX21_000166"
     CDS             complement(73515..74480)
                     /gene="trxB"
                     /locus_tag="RHX21_000166"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDV1985412.1"
                     /translation="MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQL
                     TTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLNGDNG
                     EYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVE
                     EALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGV
                     TGVRLRDTQNSDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQ
                     TSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK"
     gene            75025..75519
                     /gene="lrp"
                     /locus_tag="RHX21_000167"
     CDS             75025..75519
                     /gene="lrp"
                     /locus_tag="RHX21_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001591745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-responsive transcriptional regulator
                     Lrp"
                     /protein_id="HDV1985413.1"
                     /translation="MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTP
                     CLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEE
                     IQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLV
                     IKTR"
     gene            75654..79760
                     /gene="ftsK"
                     /locus_tag="RHX21_000168"
     CDS             75654..79760
                     /gene="ftsK"
                     /locus_tag="RHX21_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDV1985414.1"
                     /translation="MSQEYTEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSF
                     NPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQS
                     SDEYIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHS
                     SGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYE
                     DDEEYEDENHGKQHESRRARILRGALARRKRLAEKFINPMGRQTDAALFSGKRMDDDE
                     EITYTARGVAADPDDVLFSGNRATQPEYDEYDPLLNGAPITEPVAVAAAATTATQSWA
                     APVEPVTQTPPVASVDVPPSQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQ
                     YNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAAEQPVQQPYYATAPEQPAQQPYYAPA
                     PEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQSVEQQPVVEPEPV
                     VEETKPARPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVP
                     PVEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSGGPRPQVKEGIGPQLPRPKR
                     IRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDELARQFA
                     QTQQQRYGEQYQHDVPVNAEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFSLDDF
                     EFSPMKALLDDGPHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVPPQQQYQQPQQPV
                     APQPQYQQPQQQVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQQQD
                     TLLHPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEPVDTFALEQMARLVEARLADF
                     RIKADVVNYSPGPVITRFELNLAPGVKAARISNLSRDLARSLSTVAVRVVEVIPGKPY
                     VGLELPNKKRQTVYLREVLDNAKFRDNPSPLTVVLGKDIAGEPVVADLAKMPHLLVAG
                     TTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDA
                     ANALRWCVNEMERRYKLMSALGVRNLAGYNEKIAEADRMMRPIPDPYWKPGDSMDAQH
                     PVLKKEPYIVVLVDEFADLMMTVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVIT
                     GLIKANIPTRIAFTVSSKIDSRTILDQAGAESLLGMGDMLYSGPNSTLPVRVHGAFVR
                     DQEVHAVVQDWKARGRPQYVDGITSDSESEGGAGGFDGAEELDPLFDQAVQFVTEKRK
                     ASISGVQRQFRIGYNRAARIIEQMEAQGIVSEQGHNGNREVLAPPPFD"
     gene            79915..80526
                     /gene="lolA"
                     /locus_tag="RHX21_000169"
     CDS             79915..80526
                     /gene="lolA"
                     /locus_tag="RHX21_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010354356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein chaperone LolA"
                     /protein_id="HDV1985415.1"
                     /translation="MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQK
                     VTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWL
                     KDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQ
                     FSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK"
     gene            80537..81880
                     /gene="rarA"
                     /locus_tag="RHX21_000170"
                     /gene_synonym="mgsA"
     CDS             80537..81880
                     /gene="rarA"
                     /locus_tag="RHX21_000170"
                     /gene_synonym="mgsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein
                     RarA"
                     /protein_id="HDV1985416.1"
                     /translation="MSNLSLDFSDNTFQPLAARMRPENLAQYIGQQHLLAAGKPLPRA
                     IEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNR
                     NAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTITFIGATTENPSFELNSALLSRARVY
                     LLKSLSTEDIEQVLTQAMEDKTRGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMM
                     ADMAEVDDSGKRVLKPELLTEIAGERSARFDNKGDRFYDLISALHKSVRGSAPDAALY
                     WYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTRVGPAEGERAIA
                     QAIVYLACAPKSNAVYTAFKAALADARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYA
                     HDEANAYAAGEVYFPPEIAQTRYYFPTNRGLEGKIGEKLAWLAEQDQNSPIKRYR"
     gene            81971..83263
                     /gene="serS"
                     /locus_tag="RHX21_000171"
     CDS             81971..83263
                     /gene="serS"
                     /locus_tag="RHX21_000171"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDV1985417.1"
                     /translation="MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKT
                     ENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALT
                     IPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGS
                     RFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLF
                     HTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGR
                     DTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMG
                     FGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSG
                     LAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG"
     gene            83502..85946
                     /gene="dmsA"
                     /locus_tag="RHX21_000172"
     CDS             83502..85946
                     /gene="dmsA"
                     /locus_tag="RHX21_000172"
                     /EC_number="1.8.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415414.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit A"
                     /protein_id="HDV1985418.1"
                     /translation="MKTKIPDAVLAAEVSRRGLVKTTAIGGLAMASSALTLPFSRIAH
                     AVDSAIPTKSDEKVIWSACTVNCGSRCPLRMHVVDGEIKYVETDNTGDDNYDGLHQVR
                     ACLRGRSMRRRVYNPDRLKYPMKRVGARGEGKFERISWEEAYDIIATNMQRLIKEYGN
                     ESIYLNYGTGTLGGTMTRSWPPGNTLVARLMNCCGGYLNHYGDYSSAQIAEGLNYTYG
                     GWADGNSPSDIENSKLVVLFGNNPGETRMSGGGVTYYLEQARQKSNARMIIIDPRYTD
                     TGAGREDEWIPIRPGTDAALVNGLAYVMITENLVDQAFLDKYCVGYDEKTLPASAPKN
                     GHYKAYILGEGPDGVAKTPQWASQITGVPADKIIKLAREIGSTKPAFISQGWGPQRHA
                     NGEIATRAISMLAILTGNVGINGGNSGAREGSYSLPFVRMPTLENPIQTSISMFMWTD
                     AIERGPEMTALRDGVRGKDKLDVPIKMIWNYAGNCLINQHSEINRTHEILQDDKKCEL
                     IVVIDCHMTSSAKYADILLPDCTASEQMDFALDASCGNMSYVIFNDQVIKPRFECKTI
                     YEMTSELAKRLGVEQQFTEGRTQEEWMRHLYAQSREAIPELPTFEEFRKQGIFKKRDP
                     QGHHVAYKAFREDPQANPLTTPSGKIEIYSQALADIAATWELPEGDVIDPLPIYTPGF
                     ESYQDPLNKQYPLQLTGFHYKSRVHSTYGNVDVLKAACRQEMWINPLDAQKRGINNGD
                     KVRIFNDRGEVHIEAKVTPRMMPGVVALGEGAWYDPDTKRVDKGGCINVLTTQRPSPL
                     AKGNPSHTNLVQVEKV"
     gene            85957..86574
                     /gene="dmsB"
                     /locus_tag="RHX21_000173"
     CDS             85957..86574
                     /gene="dmsB"
                     /locus_tag="RHX21_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit B"
                     /protein_id="HDV1985419.1"
                     /translation="MTTQYGFFIDSSRCTGCKTCELACKDYKDLTPEVSFRRIYEYAG
                     GDWQEDNGVWHQNVFAYYLSISCNHCEDPACTKVCPSGAMHKREDGFVVVDEDVCIGC
                     RYCHMACPYGAPQYNETKGHMTKCDGCYDRVAEGKKPICVESCPLRALDFGPIDELRK
                     KHGDLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPKEV"
     gene            86576..87439
                     /gene="dmsC"
                     /locus_tag="RHX21_000174"
     CDS             86576..87439
                     /gene="dmsC"
                     /locus_tag="RHX21_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit
                     DmsC"
                     /protein_id="HDV1985420.1"
                     /translation="MGSGWHEWPLMIFTVFGQCVAGGFIVLALALLKGDLRAEAQQRV
                     IACMFGLWVLMGIGFIASMLHLGSPMRAFNSLNRVGASALSNEIASGSIFFAVGGIGW
                     LLAMLKKLSPALRTLWLIVTMVLGVIFVWMMVRVYNSIDTVPTWYSIWTPMGFFLTMF
                     MGGPLLGYLLLSLAGVDGWAMRLLPAISVLALVVSGVVSVMQGAELATIHSSVQQAAA
                     LVPDYGALMSWRIVLLAVALCLWIAPQLKGYQPAVPLLSVSFILLLAGELIGRGVFYG
                     LHMTVGMAVAS"
     gene            complement(87475..88101)
                     /locus_tag="RHX21_000175"
     CDS             complement(87475..88101)
                     /locus_tag="RHX21_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDV1985421.1"
                     /translation="MTKPYVRLDKNDAAVLLVDHQAGLLSLVRDIEPDKFKNNVLALG
                     DLAKYFNLPTILTTSFETGPNGPLVPELKAQFPDTPYIARPGNINAWDNEDFVKAVKA
                     TGKKQLIIAGVVTEVCVAFPALSAIEEGFDVFVVTDASGTFNEITRHSAWDRMSQAGA
                     QLMTWFGVACELHRDWRNDIEGLATLFSNHIPDYRNLMTSYDTLTKQK"
     gene            88415..89563
                     /locus_tag="RHX21_000176"
     CDS             88415..89563
                     /locus_tag="RHX21_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1985422.1"
                     /translation="MSTYTRPVMLLLSGLLLLTLAIAVLNTLVPLWLAQEHMSTWQVG
                     VVSSSYFTGNLVGTLLTGYVIKRIGFNRSYYLASFIFAAGCAGLGLMIGFWSWLAWRF
                     VAGVGCAMIWVVVESALMCSGTSRNRGRLLAAYMMVYYVGTFLGQLLVSKVSTELMSV
                     LPWVTGLTLAGILPLLFTRVLNQQAENHDSTSITAMLKLRQARLGVNGCIISGIVLGS
                     LYGLMPLYLNHKGVSNASIGFWMAVLVSAGILGQWPIGRLADKFGRLLVLRVQVFVVI
                     LGSIAMLSQAAMAPALFILGAAGFTLYPVAMAWACEKVEHHQLVAMNQALLLSYTVGS
                     LLGPSFTAMLMQNFSDNLLFIMIASVSFIYLLMLLRNAGHTPKPVAHV"
     gene            89773..91203
                     /locus_tag="RHX21_000177"
     CDS             89773..91203
                     /locus_tag="RHX21_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415419.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDV1985423.1"
                     /translation="MAGNVQEKQLRWYNIALMSFITVWGFGNVVNNYANQGLVVVFSW
                     VFIFALYFTPYALIVGQLGSTFKDGKGGVSTWIKHTMGPGLAYLAAWTYWVVHIPYLA
                     QKPQAILIALGWAMKGDGSLIKEYSVVALQGLTLVLFIFFMWVASRGMKSLKIVGSVA
                     GIAMFVMSLLYVAMAVTAPAITEVHIATTNITWETFIPHIDFTYITTISMLVFAVGGA
                     EKISPYVNQTRNPGKEFPKGMLCLAVMVAVCAILGSLAMGMMFDSRNIPDDLMTNGQY
                     YAFQKLGEYYNMGNTLMVIYAIANTLGQVAALVFSIDAPLKVLLGDADSKYIPASLCR
                     TNASGTPVNGYFLTLVLVAILIMLPTLGIGDMNNLYKWLLNLNSVVMPLRYLWVFVAF
                     IAVVRLAQKYKPEYVFIRNKPLAMTVGIWCFAFTAFACLTGIFPKMEAFTAEWTFQLA
                     LNVATPFVLVGLGLIFPLLARKANSK"
     gene            complement(91204..92112)
                     /locus_tag="RHX21_000178"
     CDS             complement(91204..92112)
                     /locus_tag="RHX21_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV1985424.1"
                     /translation="MRMNMSDFATFFAVARNQSFRAAGDELGLSSSAISHSIKTLEQR
                     LKIRLFNRTTRSVSLTEAGSNLYEQLRPAFDEIQIMLDEMNDFRLTPTGTLKINAARV
                     AARIFLMPLLVGFTREYPDIKVELTTDDSLVDIVQQGFDAGVRLSGIVEKDMISVAIG
                     PPVKLCVAATPEYFARYGKPRHPHDLLNHQCVVFRYPSGKPFHWQFAKELEIAVAGNI
                     ILDDVDAELEAVLMGAGIGYLLYEQIKEYLDTGRLECVLEDWSTERPGFQIYYPNRQY
                     MSCGLRAFLDYVKTGQICQSQRHRPQ"
     gene            92212..92802
                     /locus_tag="RHX21_000179"
     CDS             92212..92802
                     /locus_tag="RHX21_000179"
                     /EC_number="1.6.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H oxidoreductase"
                     /protein_id="HDV1985425.1"
                     /translation="MQSERIYLVWAHPRHDSLTAHIADAIHQRAMERKIQVTELDLYR
                     RNFNPVMTSEDEPDWKNMDKRYSPEVHQLYSELLEHDTLVVVFPLWWYSFPAMLKGYI
                     DRVWNNGLAYGDGHKLPFNKVRWVALVGGDKESFVQIGWEKNISDYLKNMCSYLGIED
                     ADVTFLCNTVVFDGEELHASYYQSLLSQVRDMVDAL"
     gene            complement(92884..93624)
                     /gene="pflA"
                     /locus_tag="RHX21_000180"
     CDS             complement(92884..93624)
                     /gene="pflA"
                     /locus_tag="RHX21_000180"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase 1-activating protein"
                     /protein_id="HDV1985426.1"
                     /translation="MSVIGRIHSFESCGTVDGPGIRFITFFQGCLMRCLYCHNRDTWD
                     THGGKEVTVEDLMKEVVTYRHFMNASGGGVTASGGEAILQAEFVRDWFRACKKEGIHT
                     CLDTNGFVRRYDPVIDELLEVTDLVMLDLKQMNDEIHQNLVGVSNHRTLEFAKYLANK
                     NVKVWIRYVVVPGWSDDDDSAHRLGEFTRDMGNVEKIELLPYHELGKHKWVAMGEEYK
                     LDGVKPPKKETMERVKGILEQYGHKVMF"
     gene            complement(93816..96098)
                     /gene="pflB"
                     /locus_tag="RHX21_000181"
     CDS             complement(93816..96098)
                     /gene="pflB"
                     /locus_tag="RHX21_000181"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HDV1985427.1"
                     /translation="MSELNEKLATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFL
                     AGATEATTTLWDKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQT
                     EAPLKRALIPFGGIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRC
                     RKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTI
                     RLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMS
                     FGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIW
                     ATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVS
                     IDTSSLQYENDDLMRPDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGG
                     VDEKLKMQVGPKSEPIKGDVLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYE
                     ASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVKPIRDEDGLAIDFEIEGEYPQ
                     FGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGR
                     RAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVR
                     KTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRF
                     NSLTKEQQQDVITRTFTQSM"
     gene            complement(96153..97010)
                     /gene="focA"
                     /locus_tag="RHX21_000182"
     CDS             complement(96153..97010)
                     /gene="focA"
                     /locus_tag="RHX21_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate transporter FocA"
                     /protein_id="HDV1985428.1"
                     /translation="MKADNPFDLLLPAAMAKVAEEAGVYKATKHPLKTFYLAITAGVF
                     ISIAFVFYITATTGTGTMPFGMAKLVGGICFSLGLILCVVCGADLFTSTVLIVVAKAS
                     GRITWGQLAKNWLNVYFGNLVGALLFVLLMWLSGEYMTANGQWGLNVLQTADHKVHHT
                     FIEAVCLGILANLMVCLAVWMSYSGRSLMDKAFIMVLPVAMFVASGFEHSIANMFMIP
                     MGIVIRDFASPEFWTAVGSAPENFSHLTVMNFITDNLIPVTIGNIIGGGLLVGLTYWV
                     IYLRENDHH"
BASE COUNT        23682 a        24068 c        25666 g        23687 t
ORIGIN      
        1 acctgtaata tattgaatct gcaggacttt gtaggccaga taaggcgtta atgccgcatc
       61 aggcattaag aaagcgcact tgtcagcaat ctgagtaacg tcgaatcgat tttcttaatc
      121 ccacatcaat tcacttccat taactctcaa acatccatgc ccaacgctcg cttaccgtga
      181 atgttgaggt cggcaagcgt aaagcgtcct tcccagtttg tttcatagtc ctcgcgcggg
      241 aagtcgcccg gcgatgcgcc tttttccagt gcggccttca ccttgtgcgc gtaggcaaga
      301 tttttctcgc acatcggtgc cgcaggaatg tacatcacgt tgccccagcc ctgttgattt
      361 tcaacggggg caacggaatg gatgacgtcg cagtgccacc agacggagtc tccggcttcg
      421 agttttggaa tgctggttaa cgcctcaatc aacagtggat gccattgctc tgataccggc
      481 aatactcttc cgggcgctac gccgcacagt tcatcctccg gcacatcatc aagcagcgga
      541 cgtaacagta cgtacgccat ggcttcagga atgggcacga cgtgcagcag cccctgacca
      601 ggcagcatat cagagagcgc tgtccagccc tggaatgtcc gaaacacgga acatttggtg
      661 gtgttgtcca ccgtgtactc ttcaacttcc gtacgatgtg ccgcatgcca gggatcatat
      721 tgcgccagat tgccattaaa gacgttggcg aaaacgcgct gatacgctgg aagcagccag
      781 cgttccagcg ccccggagtc ggtatgcgct ccaagacctt tggaggtcgt tccgggcgga
      841 cggcggcgga tacggtcagg gtagatgacg ctcacatccg ggttaaacca ttgctttcca
      901 tcactttcaa atgtccacag acgattgaga aacgactgcg cattcgccat ttcttcactc
      961 tggcgggcct gcatttgcgc ctgcgaccag tagatggggt aaatctcggg acgtgaagcg
     1021 ctgagcgtcc cgaagaaatt atcgccgggg cctttgtaga cctcgtcaaa gcggttgcgg
     1081 tccagatagt ccagcatcga ctgatcccag cctagcgctt gttcgcgggg gaaatggcct
     1141 tttatcaccg cacaaccgcg acgtttaatc tgttcgcgct gatctgcagt aacatgacct
     1201 gctttgatat cggcataaga cagcaccggc cagacggcat cgccctgtgc tttgagtgcg
     1261 ttgatttcag ccactcgcgt ggcaatgtca tcgcttagct gattaaagat ctgctggacg
     1321 tcgccaagct gcgcccgcag cgcgtgcttc atctgacgga tagctgcttt gtgatcggca
     1381 ggcaatgtgt cgctggtaaa agtagaagcc ataaccacct ctcattaact ttcattcgaa
     1441 accattctga tttgcatgtg acaatataag ttataaataa gttaatgcaa gtttaatgat
     1501 ttgatgtgat gtacaggatg taaaaagaag ggaaaaccgg agcgcacggc tccggtagag
     1561 aggtcagctg ttaaaagggg atgtgttatc cagcaccgcc tgaatcacat tcagcgcgcc
     1621 ttcatgatta ttatcatcgg tagcgtaacg ggcgatttgt ttaatgtttt ccgcagcatt
     1681 gcccatcgca aaggaataac gcgccatttt cagcatctcc gcatcgttac cgctgtcgcc
     1741 aatcgctacc acattttgcg gtgacagatc ccagcgtttc agtaaccgcg aaataccgtt
     1801 tgctttatgt agaccgggaa taatcaggtc gataaagcca aaaccactgg tgacgggttt
     1861 cataatgcca tcgagcgcta tgtgcagttt gtcgatcact aacgggattt gttcatctgg
     1921 caggttgagc gaaaacttga acagtacgtc gtcaatctcc tgataatctt ttacagcttt
     1981 caggcgatgg tagtgttttg ccatcagtgc gacaaatgct tcgggggcat tttcgctgac
     2041 atatgcactt tgcagaccgc aggcgacaaa attgagttgc ttatctttta gcaactcgcc
     2101 aataacaatc cgcgattcat gtcgggtcag ttcgccgtgg aacagttgct tgccatgttc
     2161 gtaaaccagt gcgccgtttt ccgcgacaaa agagatctca tcctttagct caggaaagaa
     2221 cgaaataagc tggtaatact gattaccgct ggcgacaacg aactcaatgc cgcgcttttt
     2281 cagttcctga tattgcgcca taaaacgtgg ttggttgtac gttttggcgt cgttaagaaa
     2341 agtaccgtcc atgtctgtga cgataacttt tacgctcata ggtgtgctcc tggctcgaaa
     2401 atgaaaccgt aacagtgtaa taacaatgtg acgcagagca caaattatat ttcgaatgaa
     2461 agtaaggatg aaattgatga tgtgaatgat ttagcccggc gacgccgcag ccgggccgaa
     2521 gagattacag catatgttca gtacgagcga tgatatcgtc ctgagcgtct ggagagagcg
     2581 cggtgaagaa ggcggaataa cccgcgacac gcactaccag atcgcggtac tgatccggat
     2641 gttttttcgc ctccagcagc gtttcgcggg aaacgatgtt gtactgaata tgccagcctt
     2701 tatgcacctc gaagaaggtg cgcagcagga tcatcagctt ctgcttgtca gattcgttct
     2761 ccagcgttgc cggattcagt ttctggttga gcaacacgcc gccgagaatc gctgccgtag
     2821 gcagtttacc caccgagcca atgaccgcag tagggccgag atggtcagta ccagaggccg
     2881 gactagcgcc ttctgccagc ggggtgtggg ctttacgccc gtccggcgtt gccatagttt
     2941 gcgcgccaaa cggtacgtta gcggagatag atgacgtacc cgcgtaatag ttgccgccaa
     3001 ccggaccacg accgtagcgc ggattatggt actgtttcag ttcgtcgata taggtctgat
     3061 aagcgcgagc cagcagcgta tcgacagtat catcgtcgtt gccgtacttc ggcgcaccgt
     3121 taatcagccg ctgacgcagt tgctcatgag tcaggccatc gaagtcatcc gccagtgcgg
     3181 cagccagctg ttgctgacca atcgcgccct gttcaaatac cagtttcttc actgccgcca
     3241 ggctgttgcc gaggttggca atgccaacct gcaggccaga aacccagtca tatttcgcgc
     3301 cgccttgctt gatacttttc gctcgctcaa tacagtcatc caccagcgcc gagcagagaa
     3361 tatcgtgcac gttctcttcc agcatggtgt cgacgacata ttcgatttcg attgatttac
     3421 gcgtgtaata acggatttgc gtatcccacg cgtccattac ttcatcgaaa ttgttaaagt
     3481 tgcctgccga caacgctttt tcttgtggca ggaacacttt gccgctggtg gcatcacgcc
     3541 cgccttccag cgccgccagc atcacgcggg cgaagttgat aaagctcatg ccggtacagc
     3601 gatagcccca tttgccaccg acggcggttt cgatacaacc aatcgctgcg tagtcgtaag
     3661 cgtcctgcgg ttcaataccg agtttaataa attccgggat cacgatttcg tcgttgttga
     3721 acgccggcat cccgaagccg caacggatca cctgtacgca ggcgtcgagg aaatcattac
     3781 tcattcctgc atggtaacgc acgctgaggt taggctgagt ggaacgcagg cgaccgcagg
     3841 attcgaggat cgcgtaagag aggggattca ctgcatccat tggttgacca tcaaccagat
     3901 tttgtccgcc aatggtaacg ttctgataca gcggacttcc cgcagaggct tttgagtgtg
     3961 agccggagcg gatcttgttc acttccagca gtttcagcca gcagctatgt agcatctcga
     4021 tggcgtgttc gcgatccagc gtctggttga gttcaacgtc gcggcgatag tacgggtaga
     4081 gatactggtc catacgacca aacgataccg agtgaccgtt agattcgatc tgcaaaatca
     4141 attggatgaa gtaacacagt tgcagcgcct gccagaaagt ctgcggcggc tggtgggcga
     4201 taagatcgca gttttctgcc atcgtcagca gttcatcgcg acggctttcg cgagtttcgg
     4261 tagcagccat ttcacgcgcc agggcagcga aacgttcaat gtgttcactg actgccacca
     4321 gcacgatatc aatcgctttc aggaattgtt cgccatgtaa atcttccagc accgtcagat
     4381 tgatgcgcga gcgacgttcc gctactttct cacgcagacc atcaagacct ttttccagca
     4441 gcagcgggaa attcaccgcc aggtgcgcat cgccggaggt catattgcct tccgctttaa
     4501 tgattccggt cgccagcaga cctttttgct catcggtaaa catgccgtag cagcgatcct
     4561 gtacggtctg accgcgccac cacgggcaca cttcatgcag aacgcgtttg ttctcttcgc
     4621 tcaccgcaaa gccagcaccg ggacgatctg ccagatcatc aatctctttt tcgatccacg
     4681 agacagtata ttccgggaag atcggcgcgg cgcgaacttc gcttgcctgg ttgccaatga
     4741 tcaactcatc gtgtttgatc cagatggtgc gattcgccag gtgatgcgcc agtgccagcg
     4801 cgcgacgtac cgggatcggc ttatcgagat gttgttgata catctcggta tagtgctgcg
     4861 cgcgctcggt acagactggc ggtttcacaa tatgcaccag cgcatttttg tgcgctttaa
     4921 tgcggtcgct gagcgtgtcc agtttcagtg tggtcatggt tgttatcctc gtaaggtcgc
     4981 ggttaaccct ttctggcagg catactgctg ggcaaagtcg agcagttctg gcgcatcaag
     5041 cggtttttcc ggggcgtcat agggcagatt aagtaagtga tatttgttga tgcccagcgt
     5101 gtggtagggc agaaaatgaa tttcgccaac gtgcagctcg tcggcggcaa aatcggtaat
     5161 ggcttttaca gaggtttcgt cggcattaaa gccctgaatc agcggcacgc ggataatgat
     5221 ttttttgccc gctgcggcga gttttttcag gttatccagc accctggcgg cgttaccgtc
     5281 ggtccactgt ttaaacggcg cgtcggcaac gtgttttaaa tcggcaagaa acagatcgat
     5341 atagggcaga gaaggggcga tatatttcca cggcacatgc agacaggttt ctaccgcagt
     5401 atgaatgccg gcctcgtggc tggcttgcag tagcgccatc gccatttccg gctgcataaa
     5461 gggttcacca cccgaaagcg ttaaaccgcc gccgctgcga tcataaaacg gtttatcgcg
     5521 cagaacggtc gtcatgatct cctcaacgct tttcacttca ccacacacgg ttaatgcctg
     5581 tgtcggacag cagtcggtta acgccgtcag atgctccggg gttaactttt cccgatgaat
     5641 aagcaaacca ttcagcgcgc gctcaatcac ttccggcgcg gccttagcgc acagctcgca
     5701 gccttccaga cacagtcgtg cgtcatacag cagatcctgc gtgcgggcgc ggctttccgg
     5761 gttctgacac cagcggcagc ccagcgaaca gcctttaaga aatacgaccg tgcggatacc
     5821 ggggccatca tgggtcgagt agcgctgaat attgaaaatc atagttgcct ctctgtttcg
     5881 ttcaaacatt aaaatacttt cgaatgaaag ttagattgat gtgcgtcaac tgttcagaga
     5941 gttttcccgt gatagtctac attcagacaa aaagtacatt ttgaggatgg ttatggaact
     6001 gtatctggat acttcagacg ttgttgcggt gaaggcgctg tcacgtattt ttccgctggc
     6061 gggtgtgacc actaacccaa gcattatcgc cgcgggtaaa aaaccgctgg atgttgtgct
     6121 tccgcaactt catgaagcga tgggcggtca ggggcgtctg tttgcccagg taatggctac
     6181 cactgctgaa gggatggtga atgacgcacg taaattgcgt tctattattg cggatatcgt
     6241 ggtgaaagtt ccggtgaccg ccgaggggct ggcagctatt aagatgttaa aagcggaagg
     6301 gattccaacg ctgggaaccg cggtatatgg cgcagcacaa gggctgctgt cggcgctggc
     6361 aggtgcggaa tatgttgcgc cttacgttaa tcgtattgat gctcagggcg gtagcggcat
     6421 tcaggctgtg accgacttac accagttatt gaaaatgcat gcgccgcagg cgaaagtgct
     6481 ggcagcgagt ttcaaaaccc cgcgtcaggc gctggactgc ttactggcag gatgtgaatc
     6541 aattacgctg ccactggatg tggcacaaca gatgattagc tatccggcgg ttgatgccgc
     6601 tgtggcgaag tttgaacagg actggctggg agcgtttggc agaacgtcga tttaaccgga
     6661 cgttctgcat cctcataaat tgctgatgac gtggcggagt gcaccgatgc ctgccgcgct
     6721 tggaaatctg tgcccgaacc gtaggccaga taaggcgttc acgccgcatc tggcgtctgg
     6781 agcaaatgcc tgatgcgacg cttgtcgcgt cttatcaggc ctggaggtgg caattactgc
     6841 ccgcacacct cacaccccgg attgcgcatc agtttcattt cgcgaaactg acaggtcatc
     6901 gcatcgtaca tgacgatttt cccgctggcc ggtttgccat aacctgccag cagtttgatc
     6961 gcttccattg cctgcaacga accaattacg ccgatcaacg gtgccatcac gcctgcttct
     7021 acgcaggtta atgcgttctc gccaaacaaa cggctaaggc agcgatagca cggttcgccg
     7081 tcctgataag tgaagaccgt gatttgccct tccatacgaa ttgccgcgcc ggaaaccagc
     7141 ggcaccttcg cggcaaaaca gcctgcgttc agttgattac gtaccgcaac gttatccgta
     7201 cagtcgagca ccagatcgtg ttcagcaatc aatgctgcaa gttctgcgtc atctagcagt
     7261 gcattgactg gcgtaatcgc gatatgtggg ttgatccgcg tcagggcgta acgggcggat
     7321 tccaccttcg gttgcccgac cgtggcatca ctgtgcagtg tctggcgttg cagattcgag
     7381 agcgaaaccg tgtcgaagtc gagcagcgtc aggttgccga caccggcgct tgccagatac
     7441 tgcgaagctg cgcagccgag tccaccgagg ccgactacca gcacacgaga atcttttagc
     7501 gcctcctgac cgtcaaaatc aaaaccgcgc agaatgattt gccggttgta gcgcagcatc
     7561 tcctgatcgc tgagttccgc cattacaggc ctccgaacaa cgcgttaaac ggttctactt
     7621 ccacccattc gcccacgtcc acattgccgc gatcgcgttc cagcacgata aagcagttgc
     7681 cgagactaaa ggagctaaat atatgtgaac cctgatgtcc ggtggtcgtc acttcaagtt
     7741 caccgtcggc gttgcgttgc agcacgccgc gctggaaatc aagacgtcct ggcgtttttt
     7801 tcaggcggga cgctgtgcgt acgcgctggc gcgcgggcag gccgctggcg gtgttgccgc
     7861 ttagttttgc cagcaaaggc tgtaccagtt gatagaaggt cagcgtcgct gaaaccgggt
     7921 tgcccggcag gccgcagaac cagctattag aaagtttacc gaacgcgaac ggtttacccg
     7981 gtttaatcgc cagcttccag aaggcgatct cccccagctc ttcaagaatg gttttggtgt
     8041 aatccgcttc acccactgaa acaccgccgg aactgatcac cacatccgcc tggctgtcgg
     8101 cttcaataaa tgcggcgcgc agggcatgtg gatcgtcgcg gataatccct aagttgatta
     8161 cctcgcatcc caactgttct aacatcaggt gtacggcgag acggttggta tcgtagattt
     8221 ggccatcgcc cagtggctga ccgggcaact ggagttcatc accggtagaa aaaagcgcta
     8281 cacgcacttt acgaatcacc ggaacttcgg caatccccag tgaagcaatc actggcagtt
     8341 cagcggtagt caggcgagtt cccgccggga aaacaaccgc acctgcagag atatcttcac
     8401 cgcgacggcg aatattttgc ccgctacgca cttcagcagt aaaacgcacg ccattgtccg
     8461 tttgttcagt ctgctcctgc atcaccactg cttcgcagcc ttccggcacc ggcgcaccgg
     8521 tcataatacg aatgcaggta cccgcaggcc attcaccatg gtacggctga ccggcaaagg
     8581 atttaccggc aacgggcagc ggttgcctgg aggcaatatc ggctaaacgc accgcgtagc
     8641 cgtccattgc ggagttatca aaccccggaa catcaagcgg cgaaacgaca tcgctcgcca
     8701 gaatacgacc aaaacactgt accagtggca gcgtttcctg ggcggtcagt ggggtgacgc
     8761 gagaaagcat ctcattaagc gcggtgtcga gcgacatcaa tccggtggta aattccatga
     8821 aaacactcct gcggaggcaa aatcgaattt gcctattatg tcagaaaaac gccacagact
     8881 gtatgccacc tcgggcgtag cgttggctcc tgcctttaca tgccatatcc atctttctat
     8941 attcaaaaat tgaatgagta attcataaaa attctgatat ttatagcaaa agtggcgagc
     9001 cacccttaat ggacgaatac tatgggcaaa gcagtcattg caattcatgg tggcgcaggt
     9061 gcaattagcc gcgcgcagat gagtctgcaa caggaattac gctacattga ggcgttgtct
     9121 gccattgttg aaaccgggca gaaaatgctg gaagcgggcg aaagtgcgct ggatgtggtg
     9181 acggaagcgg tgcgtctgct ggaagagtgt ccactgttta acgccggaat tggcgctgtc
     9241 tttacgcgtg atgaaaccca tgaactggac gcctgtgtga tggatggtaa caccctgaaa
     9301 gccggtgcgg tggcgggcgt tagtcatctg cgtaatccgg ttcttgccgc ccggctggtg
     9361 atggagcaaa gcccgcatgt gatgatgatt ggcgaagggg cagaaaattt tgcgtttgct
     9421 cgtggcatgg agcgcgtctc gccggagatt ttctccacgc ctttgcgtta tgaacaacta
     9481 ctggcagcgc gcaaggaagg ggcaaccgtc ctcgaccata gcggtgcgcc actggatgaa
     9541 aaacagaaaa tgggcaccgt gggggccgtg gcgttggatt tagacggcaa tttggcggca
     9601 gccacgtcca caggcggaat gaccaataaa ttacccggac gagttggcga tagtccctta
     9661 gtgggtgccg gatgctacgc caataacgcc agtgtggcgg tttcttgtac cggcacgggc
     9721 gaagtcttca tccgcgcgct ggcggcatat gacatcgccg cgttaatgga ttacggcgga
     9781 ttaagtctcg cggaagcctg cgagcgggta gtaatggaaa aactccctgc gcttggcggt
     9841 agcggtggct taatcgctat cgaccatgaa gggaatgtcg cgctaccgtt taacaccgaa
     9901 ggaatgtatc gcgcctgggg ctacgcaggc gatacgccaa ccaccggtat ctaccgtgaa
     9961 aaaggggaca ccgttgccac acagtgatga acttgatgcc ggtaatgtgc tggcggttga
    10021 aaatctgaat attgccttta tgcaggacca gcagaaaata gctgcggtcc gcaatctctc
    10081 ttttagtctg caacgcggtg agacgctggc aattgttggc gaatccggct ccggtaagtc
    10141 agtgactgcg ttggcattga tgcgcctgtt ggaacaggcg ggcggtttag tacagtgcga
    10201 taaaatgctg ttgcagcggc gcagtcgcga agtgattgaa cttagcgagc agagcgctgc
    10261 acaaatgcgc catgttcgcg gtgcggatat ggcgatgata tttcaggaac cgatgacatc
    10321 gctgaacccg gtatttactg tgggtgaaca gattgccgaa tcaattcgtc tgcatcagaa
    10381 cgccagtcgt gaagaagcga tggtcgaggc gaagcggatg ctggatcagg tacgcattcc
    10441 tgaggcacaa accattcttt cacgttatcc gcatcaactc tctggcggga tgcgccagcg
    10501 agtgatgatt gcgatggcgc tgtcatgccg cccggcggtg ctgattgccg atgagccaac
    10561 caccgcgctg gatgtcacta ttcaggcgca gatcctgcaa ttaatcaaag tattgcaaaa
    10621 agagatgtcg atgggcgtta tctttatcac tcacgatatg ggcgtggtgg cagagattgc
    10681 cgatcgggta ctggtgatgt atcagggcga ggcggtggaa acgggtaccg tcgaacagat
    10741 ttttcatgca ccgcaacatc cttacacccg tgcgctgtta gctgctgttc cgcaacttgg
    10801 tgcgatgaaa gggttagatt atccccgacg tttcccgttg atatcgcttg aacatccagc
    10861 gaaacaggcc ccccccatcg agcagaaaac ggtggtggat ggcgaacctg ttttacgagt
    10921 gcgtaatctt gtcacccgtt tccctttgcg cagcggtttg ttgaatcgcg taacgcggga
    10981 agtgcatgcc gttgagaaag tcagttttga tctctggcct ggcgaaacgc tatcgctggt
    11041 gggcgagtct ggcagcggta aatccactac cgggcgggcg ttgctgcgcc tggtcgaatc
    11101 gcagggcggc gaaattatct ttaacggtca gagaatcgat accttgtcac ccggcaaact
    11161 tcaggcattg cgccgggata ttcagtttat ttttcaggac ccttacgctt cgctggaccc
    11221 acgtcagacc atcggtgatt cgattatcga accgctgcgt gtacacggtt tattgccagg
    11281 taaagaagcg gctgcacgcg ttgcgtggtt gctggagcgc gtgggcctgt tacctgaaca
    11341 tgcctggcgt tacccgcatg agttttccgg cggtcagcgc cagcgcatct gcattgctcg
    11401 cgcgttggca ttgaatccga aagtgatcat tgccgacgaa gccgtctcgg cgctggatgt
    11461 ttctattcgc gggcagatta tcaacttgtt gctcgatctc cagcgtgatt tcggcattgc
    11521 gtatctgttt atctcccacg atatggccgt ggtagagcgg attagtcatc gtgtggcggt
    11581 gatgtatctc gggcaaattg ttgaaattgg tccacggcgc gcggtcttcg aaaacccgca
    11641 gcatccttat acgcgtaaat tactggcggc agttccggtc gctgaaccgt cccgacaacg
    11701 accgcagcgt gtactgctgt cggacgatct tcccagcaat attcatctgc gtggcgaaga
    11761 ggtggcagcc gtctcgttgc aatgcgtcgg gccggggcat tacgtcgcac aaccacaatc
    11821 agaatacgca ttcatgcgta gataacattc aggcggagaa taaaatggca agagctgtac
    11881 accgtagtgg gttagtggcg ctgggcattg cgacagcgtt gatggcatct tgtgcattcg
    11941 ctgccaaaga tgtggtggtg gcggtaggat cgaatttcac cacgctcgat ccgtatgacg
    12001 cgaatgacac gttatctcag gccgtagcga aatcgtttta ccaggggctg ttcggtctgg
    12061 ataaagagat gaaactgaaa aacgtgctgg cggagagtta taccgtttcc gatgacggca
    12121 ttacttacac cgtgaaattg cgggaaggca ttaaattcca ggatggcacc gatttcaacg
    12181 ccgcggcggt gaaagcgaat ctggaccggg ccagcgatcc ggcgaatcat cttaaacgct
    12241 ataacctgta taagaatatt gccaaaacgg aggcgatcga tccaacaaca gtaaagatta
    12301 ccctcaaaca gccgttctca gcgtttatta atattcttgc ccatccggcg accgcgatga
    12361 tttcaccggc agcgctggaa aaatatggca aggagattgg ttttcatccg gtgggaaccg
    12421 gaccgtatga actggatacc tggaatcaga ccgattttgt gaaggtgaaa aaattcgcgg
    12481 gttactggca gccaggattg cccaaactgg acagcataac ctggcgtccg gtggcggata
    12541 acaacacccg cgcggcaatg ctgcaaaccg gtgaagcgca gtttgctttc cccattccct
    12601 acgagcaggc cacactgctg gagaaaaaca aaaatatcga gttgatggcc agtccgtcaa
    12661 ttatgcagcg ttatatcagt atgaacgtga cgcaaaagcc gttcgataac ccgaaggtcc
    12721 gtgaggcgct gaattacgcc attaaccgtc cggcgctggt gaaagttgcc tttgcgggct
    12781 atgcaacgcc agctactggt gtggtaccgc caagtatcgc ctacgcgcaa agttataaac
    12841 cgtggcctta cgatccagtg aaagcgcgcg aattactgaa agaggcggga tatcccaacg
    12901 gtttcagtac cacgctgtgg tcgtcacata accacagcac cgcgcagaaa gtgctgcaat
    12961 ttacccagca gcagttagcg caggtcggga ttaaagccca ggtgaccgcg atggatgccg
    13021 gacagcgggc ggcagaagtt gaaggtaaag ggcaaaaaga gagcggcgtg cggatgttct
    13081 acactggctg gtcggcttca accggcgaag cggactgggc gctatcgcca ctgttcgcct
    13141 cgcaaaactg gccaccgacg ctgtttaata ccgcatttta cagcaataaa caggtggacg
    13201 acttcctggc tcaggcactg aaaactaatg atccggcgga aaagacccgc ttgtataagg
    13261 cggcgcagga tatcatctgg caagagtcgc cgtggatccc gctggtggta gaaaaactgg
    13321 tgtcggcaca cagtaaaaac ctgaccggtt tttggatcat gccagacacc ggcttcagct
    13381 ttgaagacgc ggatttgcaa taagcaacgc agggagtgga atgcttaatt acgttatcaa
    13441 acgcttactg gggttgattc cgacgctgtt tatcgtctcg gtgctggtgt ttttatttgt
    13501 gcatatgctg cccggcgatc cggcgcgatt gattgccggg cccgaagctg atgcgcaggt
    13561 tatagaactg gtgcgtcagc agctggggtt ggatcagccg ctgtatcacc agttctggca
    13621 ctatatcagc aatgctgtgc agggggattt tggcctgtcg atggtgtcgc gtcgtccggt
    13681 tgccgatgag attgccagcc gctttatgcc aacgctgtgg ctgaccataa ccagtatggt
    13741 ctgggcggtg atatttggta tggcggcggg aattatcgcc gccgtctggc gtaatcgttg
    13801 gccggatcga ttgagtatga ccattgcggt gtcggggatc tcgtttccgg catttgcgct
    13861 ggggatgctt ttaattcagg tattctccgt tgaactgggc tggctgccta ccgtgggagc
    13921 agacagttgg cagcactaca ttttaccctc cctgacgctc ggcgcggcag tggcagccgt
    13981 gatggcgcgc tttacccgcg cgtcgtttgt cgatgtttta agcgaagatt atatgcgtac
    14041 cgcgagggcg aaaggggtga gcgaaacctg ggttgtcctc aaacacgggc tacgtaacgc
    14101 gatgatcccg gtagtgacca tgatgggctt acagtttggc tttttgctcg gtggttctat
    14161 cgtggtggag aaagttttca actggcccgg acttggacgc ttactcgttg actccgtaga
    14221 aatgcgcgat tacccggtga ttcaggcgga aattctgctt ttctcgctgg aatttattct
    14281 tatcaactta gtggtggatg tgctttacgc cgccattaac ccggctatca ggtacaagta
    14341 aggatgcgac tatttaactg gcgacgtcag gcggtgttaa acgccatgcc actggtcaaa
    14401 cctgaccagg tgcgtacacc gtggcatgaa ttctggcgac gatttcgccg tcagcatatg
    14461 gcgatgaccg ccgcattatt cgttatttta ttgattgtgg tggccatttt tgcacgctgg
    14521 atcgctccct atgacgccga aaattatttt gattatgaca atctgaataa cggaccttct
    14581 ttgcagcact ggtttggcgt cgattcactg gggcgcgaca ttttcagccg tgtcctggtt
    14641 ggtgcgcaaa tctcgctggc ggcgggcgtg tttgccgtgt ttatcggtgc ggcgatcggg
    14701 acgttgctgg gcttgttggc tggatattat gaaggctggt gggatcggtt gatcatgcgc
    14761 atttgcgatg tgctgtttgc cttcccgggt attttactgg cgatcgctgt tgttgcggtg
    14821 ttgggaagcg gcattgctaa cgtgattatc gcagtcgcca ttttttccat ccccgcgttt
    14881 gcccgcctgg tgcgcggcaa cacgctggtg ttgaaacagc aaacctttat tgagtcagca
    14941 cgcagtattg gtgccagcga tatgaccatt ttattgcgtc atatcttgcc tgggaccgtc
    15001 tcgtctatcg tggtgttttt caccatgcgc attggcacct cgattatctc tgccgccagc
    15061 ctgtcatttc tcggcctcgg tgcgcagccg ccgacaccag agtggggagc aatgctcaat
    15121 gaggcacgag cggatatggt tatcgcgccg catgtcgctg tttttccggc cctggctatt
    15181 tttctgaccg tactggcgtt caatttgttg ggcgatggtt tacgcgatgc gctggatccg
    15241 aaaattaaag gatagttacg tttgaatatt gcttgaaagg gtaatcacct cacaggcaat
    15301 tattgcccta agcaagtgtt gtaactttct gctgattttg tagaatcggg taatttggtt
    15361 aaaaagccgc agcaagggac tatttttgca gcggcacagc gttcagatag ttattttgtt
    15421 aaatgtatta acatgctgag tttatacgaa aagataaaga taaggctgat aattttattt
    15481 ttattggcag cactgtcatt tattggtctt tttttcatca ttaactatca actggtatcg
    15541 gaacgcgcgg taaaacgtgc cgatagccgc tttgaactta ttcagaaaaa cgttggctat
    15601 ttctttaaag atattgaacg ttcggccctg acattaaagg actcactgta tttattaaaa
    15661 aatacagagg agattcaacg cgccgtgatt ctgaaaatgg aaatgatgcc atttttagac
    15721 tcggtgggac tggtacttga tgataataaa tattatctct tttcgcggag ggcgaatgat
    15781 aaaatcgttg tttatcatca ggaacaagta aatggaccgc ttgtcgacga gtcagggcgg
    15841 gttatttttg ccgattttaa cccatcgaaa cgaccgtggt cggtggcttc agatgactct
    15901 aacaacagct ggaatccggc atacaattgc tttgatcgtc cgggtaaaaa atgtatctct
    15961 tttacgctac gtatcaacgg caaagatcac gatttgttag cggtagataa aattcatgtc
    16021 gatttaaact ggcggtatct gaacgagtat cttgatcaaa tcagcgctaa tgatgaagtt
    16081 ctatttttga aacaaggtca tgagatcatt gccaagaatc aactcgctcg tgaaaaactg
    16141 attatttata atagcgaagg taattataat attattgatt ctgtcgatac ggagtatatt
    16201 gcaaagacat cagcagtgcc aaataatgca ttgttcgaaa tctattttta ttatcctggc
    16261 ggtaatttat tgaacgcatc agataaactt ttttatctac cgtttgcgtt cattattatc
    16321 gtgttgctgg tggtatattt catgaccact cgtgtgttcc gtcggcaatt ttctgaaatg
    16381 accgagctgg ttaatacgct ggcgtttttg cccgactcaa cggatcagat cgaggctctg
    16441 aaaattcgcg aaggcgatgc gaaagagatt atcagcatca aaaattcgat cgcggaaatg
    16501 aaagatgccg aaattgaacg gtcaaataaa ttgctctcac tgatctctta cgatcaggaa
    16561 agcggtttta ttaaaaatat ggcgattatt gagtccaaca ataatcagta tctggctgtg
    16621 gggatcatca aactgtgtgg tctggaagcc gtggaagcgg tgtttggtgt tgatgaacgc
    16681 aataaaatcg tcaggaaatt gtgtcagcga attgccgaga aatatgcgca atgctgcgat
    16741 atcgtgacat tcaatgccga tctctattta cttctgtgtc gggaaaatgt acagacattt
    16801 acccgtaaaa tagcgatggt aaacgatttt gacagcagct ttggctaccg caatctgcgc
    16861 atccataagt ctgccatttg tgaacctttg cagggggaaa acgcctggag ttacgcagaa
    16921 aaactgaaac tggcgatttc cagtatccgt gaccatatgt tctccgagtt tattttctgt
    16981 gatgacgcga aactcaacga aatagaagag aatatctgga ttgcgcgtaa tattcgccat
    17041 gcaatggaaa ttggcgaact attcctcgtc tatcaaccga tcgttgatat taacacccgc
    17101 gccattctgg gcgcggaggc gttgtgccgt tgggtttctg cggagcgggg gatcatttca
    17161 ccgctgaagt tcattaccat tgctgaagat atcgggttta tcaatgagct gggttatcag
    17221 attattaaaa cggcaatggg tgaattcaga cattttagtc agcgtgcgtc gctgaaggat
    17281 gatttcttac tgcatattaa tgtttcgccc tggcagttaa acgaaccgca ctttcatgag
    17341 cgttttacca ccatcatgaa agaaactggc ctgaaggcga acagcctctg tgttgagatc
    17401 actgaaaccg tgattgagcg aattaatgaa catttttatc tcaatattga acaactgcgt
    17461 aaacaagggg tacggatatc gattgatgac tttggcaccg gtttgtcaaa cctgaaacgt
    17521 ttttatgaaa ttaatccaga cagcataaag gtggactcgc aatttaccgg cgatattttc
    17581 ggtactgcgg gaaaaattgt gcgcattatt ttcgatctgg cacgctataa ccggatcccg
    17641 gtgattgcgg aaggcgtaga gagcgaagac gttgcgcgcg aattaattaa attaggatgt
    17701 gttcaggctc aggggtatct gtaccagaaa cccatgccat tctccgcctg ggataaaagt
    17761 ggaaaattag taaaagagta gtttacgtat gtccagaatc aataagttcg tacttacagt
    17821 cagtctgctg atttttatca tgatttcagc agttgcctgc gggatctaca ctcaaatggt
    17881 aaaggaacgg gtgtatagcc tgaaacagtc cgttattgat actgcttttg cggtggcaaa
    17941 tattgctgaa tatcggcgta gcgtggcaat tgatcttatc aacacgctaa atcccacgga
    18001 ggaacagctg ttggttggtt tgcgcacagc ttacgccgac tcggtttccc cctcttattt
    18061 gtacgatgtc ggtccttatc tgatttccag tgacgaatgt attcaggtaa aggagttcga
    18121 gaaaaattat tgtgcagata ttatgcaggt tgtgaagtat cgacatgtca aaaatacagg
    18181 gtttatctct tttgacggta aaaccttcgt ctattacctc tatccggtaa ctcacaatcg
    18241 tagtctgata tttttgcttg gtctggagcg tttttcttta ctgtcaaaat cgctggcgat
    18301 ggacagcgag aacctgatgt tctctctatt taagaacggt aaaccggtga ccggtgatga
    18361 atataatgct aaaaacgcca tcttcaccgt ttcggaagcg atggagcact tcgcctattt
    18421 gccgaccgga ttgtacgtat ttgcgtataa aaaagatgtt tatttgcggg tctgtacatt
    18481 gattattttc tttgccgcat tggtggcagt gatatcgggt accagttgcc tctatctggt
    18541 acgcagagtg attaatcgtg gtattgtgga gaaagaagcc atcattaata accattttga
    18601 acgcgtactg gatggcgggc ttttcttttc ggctgccgat gtcaaaaaac tctacagtat
    18661 gtataactcg gcgttcctgg acgacctgac caaagcaatg ggcagaaaat cctttgacga
    18721 agatttaaaa gcgctgccgg aaaaaggcgg ttatttgtgc ctgtttgacg tcgataaatt
    18781 caaaaacatt aacgacacct tcggtcattt gctgggcgat gaagtgttga tgaaagtggt
    18841 gaaaatcctt aaatcacaga tcccggtaga taaaggtaaa atctaccgct tcggcggtga
    18901 cgaatttgcg gtgatttata cgggtggaac gctggaagag ttgctatcga ttctaaaaga
    18961 aatcgttcat ttccaggtgg gaagcattaa tttaagtacc agtatcggtg tagcgcattc
    19021 aaatgaatgt accaccgtcg aacgcttgaa aatgctggcg gatgagcggc tgtataagag
    19081 taagaaaaac ggcagggctc agataagctg gcagtaatca ttattcgcag gccggacaaa
    19141 tgattttgcc cggcctgaat taattaaacc cggctacccc acaaatcgta ctcatcggcg
    19201 tgctcgactt tcacacgcag gatatcaccc ggcttaacgt tggtttcacc attgagataa
    19261 accgcgccgt cgatttccgg tgcatctgcc atgctgcgac caatcgcgcc ttcttcgtcc
    19321 acttcgtcga taatcaccag aatttcacgg cccactttct cttgcaggcg ctcggcggaa
    19381 atctgctgct gcagctgcat gaaacggttc cagcgttctt ctttaacttc ttccggaacc
    19441 tggtcaggca gggcattggc gtctgcacct tcaaccgggc tgtatttaaa gcagccaacg
    19501 cgatccagac gcgcttcttt caggaagtcg agtagcatct ggaaatcttc ttctgtctcg
    19561 ccagggaagc cgacaataaa ggttgagcgt agggtcagtt ccgggcagat ttcgcgccac
    19621 tgtttgatgc gcgccagttg gcgatctaca gaacccggac gcttcatcag tttgagaatg
    19681 cgcgggctgg cgtgctgcaa cggaatgtcc agatacggca ggattttgcc ttctgccatc
    19741 agtgggatga cgtcgtccac atgcggataa gggtaaacgt agtgcagacg tgtccagatc
    19801 cccagtttcg ataactgttc gcacaggctg accatgctgg tttttaccgg ctcgccgttg
    19861 tggaagccag tacgatgttt aacatcaacg ccataggcgg aagtatcctg cgagatcacc
    19921 agaatctctt taacgcccgc atctaccaga cgtttcgctt cacttaacac ttcgccaatc
    19981 ggacggctca ccaggtcgcc gcgcatagac ggaataatgc agaaggtgca gcggtgatta
    20041 cagccttccg aaattttcag ataggcataa tgacgcggcg tcagtttcac accttgttct
    20101 ggcaccaggc tcaggaatgg gttgtgtttc ggttttggca cgtagtgatg aacgtgctcc
    20161 agaacctgct catagctatg aggcccggtg atttccagca ctttcgggtg gacttcgcgg
    20221 atctgatctt cttttgcccc cagacaaccg gtcacaatta ccttgccgtt ttcattcaac
    20281 gcttcaccaa tggcttccag tgattcttgt accgcgctgt caataaagcc gcaggtgttg
    20341 acgatcacca tgtccgcatc gtcatagctc ggtaccacgt cataaccttc agtgcggagt
    20401 tcggtgagaa tacgctctga atcaacaagg ttttttggac agccaaggga aacaaagccg
    20461 attttcggct ggggagttac tttgctcata gcttaaaaaa tattcagtta caggaaaggt
    20521 cagggcaggg attctacaga gttctgcata aaatttgtat cgcaatctca ttcgctggcg
    20581 gaggcgaagg aaatgtaaat tttgttaatt cggcgtgaag aattgatcct ggacagcatt
    20641 ttgctcaaaa aatagccata ctatttaatt gcaacaaggc tggaaagagg aggatcgaag
    20701 tatgttcgtt gacagacagc gaatcgatct gctgaaccgg ttgatcgacg cacgcgttga
    20761 cctcgccgca tacgtgcaac tgaggaaggc aaaaggatac atgtccgtca gcgaaagcaa
    20821 tcatctacga gataactttt ttaaactgaa tcgcgaactg cacgataaat cgctgcggtt
    20881 gaatcttcat ctggatcagg aagagtggag tgctcttcat catgctgaag aagcattagc
    20941 gacagccgca gtatgtttga tgagtgggca ccatgattgc ccgactgtta ttaccgtcaa
    21001 cgccgataag cttgaaaatt gtctgatgag cttaacgctg agtatccaga gcctgcagaa
    21061 gcacgccatg cttgagaagg cctgaaaact aagggggaga aagcgtctcc cccttcatgt
    21121 ttaagttttt gtaaaaatga atttgttatc tcctccactg actacgcttt aagccagagt
    21181 caatccggag gcgttatgca tcgacaatcc tttttccttg tgccccttat ttgtctttct
    21241 tccgctctct gggcggctcc tgcaacggta aatgtcgaag tactgcaaga caaactcgac
    21301 catccctggg cactggcctt tttacccgat aatcacggta tgttaatcac tctgcgcggc
    21361 ggcgagttgc gtcactggca agcaggaaaa ggattatctg cgccgctttc cggagttccg
    21421 gacgtttggg cgcacgggca gggcggcctg ctggacgtgg ttttagcgcc tgattttgct
    21481 cagtctcgcc gcatctggtt aagttattcc gaagttggcg atgatggcaa agccggaact
    21541 gctgtgggtt atggccgctt aagtgatgat ctctcaaaag tgaccgactt ccgcaccgtc
    21601 ttccgccaga tgccaaaact gtctaccggc aaccattttg gcgggcggct ggtattcgac
    21661 ggtaaaggtt atctttttat tgctctgggc gaaaacaatc agcgcccgac ggcgcaggat
    21721 ctggataaat tacagggcaa actggtgcgt ctgaccgacc agggcgaaat cccggatgat
    21781 aatcctttta taaaggaatc cggtgtgcgc gccgagatct ggtcttatgg cattcgtaat
    21841 ccgcaaggaa tggcgatgaa tccgtggagt aatgcactgt ggctgaatga acatggcccg
    21901 cgcggtggtg atgaaattaa tatcccgcaa aaaggcaaaa actacggctg gccgctggca
    21961 acctggggaa tcaactattc aggctttaag ataccggaag cgaaagggga gatcgtcgcc
    22021 gggaccgagc aacctgtttt ttactggaaa gattcgcccg ctgtgagcgg catggccttc
    22081 tataacagcg ataaattccc ccagtggcag caaaaattat ttattggcgc gctgaaagat
    22141 aaagatgtca ttgtgatgag cgtcaacggc gacaaagtga cagaagatgg ccgtatttta
    22201 acggacagag ggcagcgaat tcgtgatgtt cgcactggac ccgacggtta tttatacgtt
    22261 ctcaccgacg agtccagtgg ggaattactt aaagttagcc cacgcaatta gctaacggga
    22321 atcatcacca ctttgcgcac tgcggggcgt tcagtgagtt gctgatacca gcgttgcaga
    22381 tttggacgcg gtgtccaggt caggccaacg ttaaacaaat tgtagatgaa cggtgcgata
    22441 gcgatatcgc ccacaccaaa ctcgtcgcca gagaaccatt ttacttttgc cagttccgca
    22501 tcgagcaggg caaacagggc gtcgcactct ttgcaactgg catcaatggc ggcctgatcg
    22561 cgctcttccg gtggtgttct gactaatccc atcaggatcc cgcgatgagc attactgagc
    22621 gtctggtttg cccagtccat ccatttttcc gcttccgcac gacgtgccgg tgagtcgatc
    22681 cacagacgtt tttgcccgta ctgtgccgcc agatagcgga caatggcgtt tgattcccaa
    22741 agaatgagat cactttcgtc gtcacgcaac aacggcacca gcccgttagg gttcatcgcc
    22801 agaaaatcag catcgtgatt tatcccaaac tcacggcccg cgagaatttg ctcataaggt
    22861 agttccagtt cttcgagcgt cagcaatact ttttttacgt tagttgaatt attccgaccc
    22921 cacagcgtaa tcatactcac cccttttccg acaggcagcc acaggctgaa caggactccg
    22981 atggtgaagt aaagttaact tttaagcaac agctggcaaa aaaatgacac cagaagcagc
    23041 gaagcggcag gatattgcat aaactttaaa aactttacca acttacggtt tctttaagtt
    23101 tgtgtgtgcg ttattaatca ccgaacttat catacggcga tataacgtat ttttttgaat
    23161 ggatactcgg gtggcattta tgacgcaata ctcctctctc cttcgtggtc ttgcagcggg
    23221 ttctgcattt ttattccttt ttgccccaac ggcattcgcg gcggaacaaa ccgttgaagc
    23281 gccgagcgtg gatgcgcgtg catggatttt aatggattac gccagcggta aagtgctggc
    23341 agaaggcaac gcggatgaga aactggatcc cgcgagcctg actaaaatca tgaccagcta
    23401 tgtggttggg caggcgctta aggccgataa gattaaactc accgatatgg tgacggtcgg
    23461 taaagatgcc tgggcgacgg gaaatccggc actgcgtggt tcatcggtaa tgttcctcaa
    23521 accgggcgat caggtttcgg tggcagactt gaacaaaggt gtgattatcc agtccggtaa
    23581 tgacgcctgt attgcgctgg ccgattacgt tgccgggagc caggagtcat ttattggttt
    23641 gatgaatggt tatgccaaaa aactgggtct gaccaacact accttccaga cggtgcacgg
    23701 tctggatgcg ccggggcagt tcagtaccgc gcgcgatatg gcattgctgg gtaaagcatt
    23761 gatccacgat gtgccggaag agtacgccat tcataaagag aaagagttca ccttcaacaa
    23821 aattcgtcag cctaaccgta accgtctgct gtggagcagc aatctgaatg ttgatggcat
    23881 gaagacagga accacggcag gcgcgggata taatctggtt gcttcggcta cccagggcga
    23941 tatgcgttta atctccgtag tgctgggggc gaaaactgac cgtatccgtt ttaatgagtc
    24001 tgagaaatta ttgacctggg gtttccgctt ctttgaaacc gtgacgccaa ttaaacctga
    24061 tgccaccttt gtgactcagc gcgtctggtt tggtgataag agcgaagtga atcttggggc
    24121 aggtgaagcg ggctcagtga ccataccgcg tgggcagctg aaaaacctga aggcgagcta
    24181 cacgttaacg gaaccgcagc ttaccgcacc gctgaaaaaa ggtcaggttg tcgggaccat
    24241 tgatttccag cttaacggta aatccattga gcagcgtccg ctgatcgtga tggaaaatgt
    24301 ggaagagggc ggattctttg gtcggatgtg ggatttcgtg atgatgaaat tccatcagtg
    24361 gttcggcaac tggttctctt aatcttctga taaccggatg gcgcgaaacg tcatccggtt
    24421 atacgtcatt aatacatcaa cttaatacgg tgcgtctgcg cgtacttcac atactcatct
    24481 tccgggcaac aatcactcac cacaatatca aagcgtttca ggtcacccat gcgcgccgga
    24541 cgcaccttgc caaatttact gtggtcgaca accagcacat gcttttgcgc catcgacatg
    24601 gcccagtgtt ttaccggcaa ctcttcaaga ttaaaacagg tagcgccttt actgacatgc
    24661 acgcccgccg cggaataaaa agcgatatcc gggcaaaaat tattcaacgt ttgctgaaaa
    24721 tcgatgggtt tgaaaatggc gttgctggcg tgaaattcac caccgcacag aaatgcgcgg
    24781 caatggggtt tctctttcag cgccagaaag gtatttagcg aataacaaac ggcggtaaaa
    24841 gggatttcat tatcaatcgc ttcaataatc cacggcgtgg tggtgccaca gtcaaaaaag
    24901 agagtctgat cgggttctac cagtgtcgca gccatttttg ccgcccggcg tttttcttcc
    24961 accaggcggg atttttgatc gcttaacagg taatggctgg cactgcgcgg ttccagaaca
    25021 atatagccgc cgagcaaaac gacgggcgca ctgtggttgt tcagatcgcg acgaatcgtc
    25081 atctccgaaa ccccaagcag ggcggcggcg tctttaagat gtaacttatc gctgcgtttt
    25141 aattcttgca gcagctgccc gatacgctct tcgcgacgtg tttccataat ccctctgaat
    25201 agttattgaa gcgagccgct caatactaca ctttttagca gagatcagtc acgcacccag
    25261 cctttgcgga tcggtaatgc aaaacagaag cgataccacg attgcagacg ttgatagagt
    25321 ttatgcccca tcgcttgcca gataatctga gcgctaaggc agccaatcat acctgccagc
    25381 aatccaccga gcatatccag cggccagtgc acgccaagat aaacgcgcga ccaggcaatg
    25441 acgacggcca gcaccattaa aagtgagccg gaccacaggc gatgccagca taaaaatgcc
    25501 agtgcaaagg tgaaaatcac cgtaccgtgg tcgcttggga atgagtcatc cgccgcatga
    25561 tgcaggaagt tatagccgat attttcgaca aagggtcggt cgtgcggaaa aagatgtccc
    25621 atcgtccagg acacaaacag gctgaccgcc agcgcgatag cgatttttat caccagttgc
    25681 cgttgtgctg taagccccca caaccaaagc accgcggcca gcagcggtac cacggtaatc
    25741 aaatctttag caataaaaat cgccaacgag atcatccacg gagccgagtc tggcgtcgcg
    25801 ttaataagag agaatagaga gagattcaaa ttttccagca taacttcccg acgcaaagtg
    25861 attaaaaggg agccaataca ggcaagtcgt tgagaataaa gtgcaggtta aactgggtaa
    25921 agcggcatcg tcttatttcc ctcaagcggc ctgtttacgg tgggtaattg taacgggcat
    25981 aggttaaata aaacttaaag aaagcgtagc tatactcgca ataatgtaag aatgtgctta
    26041 accgtggttt cagctacaaa attcgctttc tcgttagctg tgcttttatt aaactctgcg
    26101 cgattattat tggcgaagaa attgcatgca aaataaatta gcttccggtg ccaggcttgg
    26161 acgtcaggcg ttacttttcc ctctctgtct ggtgctttac gaattttcaa cctatatcgg
    26221 caacgatatg attcaacccg gtatgttggc cgtggtggaa caatatcagg cgggcattga
    26281 ttgggttcct acttcaatga ccgcatatct ggcgggcggg atgtttttac aatggctcct
    26341 ggggccgctg tcggatcgta ttggtcgccg tccggtgatg ctggcggggg tggtgtggtt
    26401 tatcatcacc tgtctggcaa tattactggc gcaaaacatt gaacaattca ctctgttgcg
    26461 cttcttgcag ggcataagcc tctgtttcat tggcgctgtg ggatacgccg caattcagga
    26521 atccttcgaa gaggcggttt gtatcaagat caccgcgctg atggcgaacg tggcgctgat
    26581 tgctccgcta cttggtccgc tggtgggcgc ggcgtggatc catgtgctgc cctgggaagg
    26641 gatgtttgtc ttgtttgccg cattggcagc gatctccttt ttcggtctgc aacaagccat
    26701 gcctgaaacc gccacgcgta taggcgagaa actgtcactg aaagaactcg gtcgtgacta
    26761 taagctggtg ctgaagaacg gccgctttgt ggcgggggcg ctggcgctgg gattcgttag
    26821 cctgccattg ctggcgtgga tcgcccagtc gccgattatc atcattaccg gcgagcagtt
    26881 gagcagctat gaatatggct tgctgcaagt gcctattttc ggggcgttaa ttgcgggtaa
    26941 cttgctgtta gcgcgtctga cctcgcgccg caccgtacgt tcgctgatta ttatgggcgg
    27001 ctggccgatt attattggtc tgttggtcgc tgctgcggca acggttatct catcgcacgc
    27061 gtatttatgg atgaccgccg ggttaagtat ttatgctttc ggcattggtc tggcgaatgc
    27121 gggactggtg cgattaaccc tgtttgccag cgatatgagt aaaggtacgg tttctgcggc
    27181 gatgggaatg ctgcaaatgc tgatctttac cgtcggtatt gaaatcagca aacatgcctg
    27241 gctgaacggg ggcaacggac tgtttaatct cttcaacctt gtcaacggaa ttttgtggct
    27301 gtcgctgatg gttatctttt taaaagataa acagatggga aattctcacg aagggtaaaa
    27361 aaatgcctga ttgctttgtg cgatcaggca ttctcgaatt aatggtgatg gtcgtcaatc
    27421 tggtgttcga taaccatccc ttcacctacg ctggcaagat ggcgaacata aggatgcggg
    27481 cggtaagccg gagctggcgc aggagccaca tagacggttt gtggcacagt cgcgacgctg
    27541 accgcttgtg gaacgctgac tgaatcagga accacaacca ctttgtatcc actcggcaca
    27601 tcgacggtga cactttgcgc catcgccaca ccagtaaagc ccattaaaag cgcgcccaac
    27661 agtagacaat ttttcataaa catttcgcct gaaataatgc agcgggttaa tttccgcgaa
    27721 ttatgcagcc ttcattcagg tattgtgttg ccgggcgtgc tgccgttttt attggtcaaa
    27781 tggcgcttcg tgtttaagca ctttatcgat cacatccagt acgccttcac ggttattgga
    27841 gcctgcccgg tattttgccg ctgcgacgac cgcattgccg gcattttcca ttgcaaaact
    27901 aaagcctgcc tgacgcagca tctcaatatc gttaccgcca tcgccaaaga ccaccacttc
    27961 gctgtcgtct attccccata atttctgcag ttggcgaagg ccattggctt tatgtacgcc
    28021 ggggataatc agatcgatgc tgccgttgcc ggtgtggacc ggcaccataa tatcgccgat
    28081 ggcctcatgt aatgcttttt gtacttgtgg aatcagttca tcggaaagat tcaggccaaa
    28141 cttaaagaag atatcctcta agttgtcaaa gttatcgacg tattccagac ggtgataata
    28201 catttccgcc accgttttca tggcatcgtc atattttttg agcgtatagg cgctattttt
    28261 tccgcaggca ataatttcca cttccgggcg cgtcagcaaa tgttccacga cagtagtaaa
    28321 cgcatccttc gacagctcgc cattaaaaac atctttgcct tcgctcacta cccagccgcc
    28381 gttttcagcc acaaaggcaa tttcattagc aatttcaggg aagaaagaga tcaactgata
    28441 atattgattc ccgctggcga ctacaaagcg aattccttgt gctttcattt gctgatactg
    28501 agccataaac cgctcacggt tataggtttt ttgatcgctt aagaaagtac catccatgtc
    28561 taccgcaatt aatttaatgc tcatcaacta ttctccatcg ccgtctgcgt tttggtatcg
    28621 ggtttggcga cggctttcgc gacaatagcc gcgagaataa ccagcgccag tacaaccagc
    28681 attgcactac gtaatccata atgttcgccg agatagccca gcagcggcgg cccgacgagg
    28741 aaagccagat aaccggtcgt tgctaccaca ctgacgcggg ttggtgcatc ggggccggta
    28801 tcgctggcgg cagaaatggt cagcgggaag cccagcgagg cacccagtcc ccagagtaca
    28861 acagacaccc cagcgaccca ggcgctatcg acaaaaataa tcagcccaat acccaacgcc
    28921 cccattagtg cactggcccg aaccacggca acgcgactgt aacggtcgat gaaccaaccg
    28981 ccggtgaagc gtccaacggt catccccagg gtaaaaccgg cataaatcag cgagccggaa
    29041 gtagggctaa aaccgtgacc gtcaaccatt aataagggta accagtcgtt ggcagaacct
    29101 tcggcaaagg ccatcgccag caccacaaca cctatcagca gcaactggat atcgcgataa
    29161 aaaggaatgc ctttttcgcc atgctgggtg ccatcggcag catttttgcc cgtaccgtca
    29221 gggattgcct gaatggcgat ataaataggc gcgataccta ccagcgccgc caataaaatg
    29281 tgcaccgttg ccggaacgcc aaaggccgtc agtgccatcc cgacaccagc gcctgccagc
    29341 gtgcccaggc tataaaaacc gtgcatcatt ggcaaaaccg ttttattcat ttctcgctca
    29401 acggcggcac cttcaacgtt tatcgccact tccgcagaac caaaacttgc cccaaagacg
    29461 ccgagaccaa cggcaaagag caggggcgat gtcagccaga gtgccagact taatatcatc
    29521 atcccgatca atgcgcagga catcgtgacc aggatgacat tacgcgtgcc aaagcgtttc
    29581 actaaccacg ccgagcagag aataccgctc atcgaaccga tcgacagacc aaagagaaca
    29641 ccgcccattt cagcgatcga gacagagaga atatcgcgga tagcaggcgt acgggttgcc
    29701 caggacgcca ttaacaggcc tggcaaaaag aagaacataa acagcgccca ggttcggcgt
    29761 ttcaatgcat tacgtgaaga atttacggtc atagatcacg tcaaaataag aagagggaag
    29821 acaacattag caaggttgtg tacatttgta cacaattgca gagagaggaa atgacatgcg
    29881 tcgcgctaac gatccgcaac ggcgagaaaa aattatccag gccacgctgg aggcggtgaa
    29941 actttacgga atacatgctg ttacgcaccg caaaattgct acccttgccg gggtaccgtt
    30001 gggatcgatg acctactatt tttcaggaat tgatgagttg ttgctggagg cgttcagcag
    30061 ttttactgag attatgtccc ggcaatatca ggcatttttt agcgatgtta gtgatgctca
    30121 aggcgcatgc caggctatca ccgatatgat ctacagctca caggttgcaa cgccggataa
    30181 tatggagctg atgtaccagc tctacgcgct ggctagccga aaaccgctat taaaaacggt
    30241 aatgcaaaac tggatgcagc gcagtcagca aacgctcgaa caatggtttg aacccggaac
    30301 cgcccgcgcg cttgatgcgt ttattgaggg gatgacgctg cattttgtca ccgaccgtaa
    30361 gccgctatcg cgcgaggaga ttttgaggat ggttgagagg gttgcagggt agtagataaa
    30421 ttttagataa caaaaaaccc atcaaccttg aaccgaaatg gcggggttga tgggctccac
    30481 aaaatgggga catcaaagaa aagcagtggc actaattaag actgatgccc tgcggaaaag
    30541 ttctgcggtt gtgcaaaaaa atttcatttt cagggcaact tcagttttat cctaatcctg
    30601 gccataccat gacgatgatt gtccctgcca gcgtcagcag gacgttggcg attgcgtagg
    30661 tgcccgcata gcccagcgca gggatgttac tgcgagctgt atcactgatg atctccattg
    30721 ccggcgcgca ggtgcgtgcg cccatcattg cgccgaacaa cagtgcgcgg ttcattcgca
    30781 atacataagc accgaacaag aaacagataa ccacgggcac aagactgaca attaatccgg
    30841 caatcaacat ctgaccgcca atcgcgccca ggccgttatt aataccgcta ccggcgctca
    30901 gaccaacgcc tgccataaac accatcaagc cgaactcttt caccatgctt aatgcacctt
    30961 gcggaatgta accgaaggtc gggtggttag cacgcataaa gcccagcata attccggcga
    31021 ataacaaccc ggcagcgttc cccatgccga aactgaatgt gctgaactgg aaggtgatca
    31081 tcccgatcat cagcccaata acaaagaagg cgcaaaatgc cagcaggtca gtgacctggc
    31141 tgtgaatcga gataaagccg atgcgatcgg cgatggtttt tacgcgacgg gcatcaccgc
    31201 tgacttgtaa aacgtcacct ttgttaagca cgacgttgtc atctatcggc atctcaatct
    31261 ggctacgaat gacgcggtta aggaagcaac cgtgatcggt caacttcagt tgtgcgagac
    31321 gtttacctac agcgttatgg tttttaacga ccacttcttc agtgacgata cgcatgtcga
    31381 gaaggtcacg atcgaaaact tctttaccgt tacggaagct gggatcgagt cgggcatggg
    31441 cgtcgggata gcctaccaac gctatttcat cgcccatttg tagcacggca tcaccgtctg
    31501 gatttgccag aatcccgtta cgtcgaatac gttcaatgta gcagccggtt tgtcgataaa
    31561 tacccagttc acgcagattt ttgccgtcgg tccaggccac cagctccggg ccgacgcgat
    31621 aggcgcggat caccggtaaa taaaccttac ggttggcatc agtgtccagg ccacgttcgc
    31681 gggcgatttg ctgggcgctg gtctgtaagt cctgatgctg caatttcggc aagtaacgcg
    31741 caccaacaat caaactcacc agaccgatta aataggttaa ggcatacccg aggctcagat
    31801 tatccagtgc cagtgagagc tgcctgcttt ccatgccgaa atgacgcagt gtatcgccag
    31861 caccgaccag aaccggtgtc gacgtcatag agcctgctaa cataccggcc gtcaggccaa
    31921 tatcccagcc aaacagctta cctaacccta aggcgatcac cagcgcactg ccaaccatca
    31981 ccagtgctaa cattaggtaa tttttcccat cgcgaaaaaa aatggaaaaa aagttcggtc
    32041 cggcttcgac cccgacgcag aaaataaaca gcataaagcc aagattaagc gcatcggtgt
    32101 taatgctgaa atgttgttgg cctaataaca gcgatacgac taaaacgcca atggaattac
    32161 ccagttggat cgaaccaagt cgtaactttc cgagacatag cccaagcgcg aggaccacaa
    32221 ataataacag aatgtaattc ccatttaaca attcggcgac gtttatattc acggaggcta
    32281 acttcttgtt tactagtaag ctgttgaaag aaatggtaat ttacgataat gttttttacc
    32341 agaattcagg gcgcagattc attcagcgca cctaaacgat agtaaagtaa caatatattt
    32401 tactagtgta atcacattag gtatcaacgg ctatatgaat tgcgttggcc tatattagca
    32461 tggaatgcga agcggcttta tcttactgaa cgccacactg gcgaaaaatg tgttcgatag
    32521 acgcagtgtc aggaggaacg agtgaaacat aaacaacgtt gggcgggggc aatctgctgt
    32581 tttgtcctct tcattgtggt gtgccttttt ctggcgacgc acatgaaagg cgcttttcgg
    32641 gctgccgggc atcctgaaat cggcttgcta tttttcattc ttcctggagc agttgccagt
    32701 ttcttttcac agcgtagaga agtcctgaaa cctctatttg gcgcaatgct ggcggcaccc
    32761 tgttcaatgc tcattatgcg gctgtttttt tcaccgacgc gctcattctg gcaagagctg
    32821 gcatggttac taagcgcggt gttctggtgt gcgctggggg cactgtgttt cttatttatc
    32881 agtagtttgt ttaaaccaca gcacagaaaa aatcagtaaa gccctcaacg cgagggcttg
    32941 tcagacgatc aggcgtccag attttctttc acccatgcag caaaatcggt atagccgccg
    33001 atatgttgct gatcgacaaa aatctgcggc acggtttcta cgggtttacc tgccttttgt
    33061 tgtagatctt ctttagtgat cccttccgca cgaatatcta catactgata ctgaaaatca
    33121 tcgcgttcat tgctcaattt ctcagccaga tcttttgcac gcacacagta agggcaaccc
    33181 gaacgaccaa aaataacggt ttgcattatt tctctcctca tagatttatg cctgtaatga
    33241 tcacgctaaa atgtattcgc tgaaagtagg tttaacctgt tgcattaatt gctaaaagct
    33301 ataactgtta aacacaatac agtgaaaagt tttagactga aggctcactt tgcagaggga
    33361 agcgtatgcg cgcgatcggt aaattgccta aaggcgtgtt gatactggaa tttatcggaa
    33421 tgatgctact ggcggtggcg ctgctgtcgg taagcgactc cctgtcgctg cctgagccat
    33481 tttctcggcc agaagtgcag attctgatga tttttctcgg tgttttgctc atgcttcccg
    33541 ctgcggtggt ggttattctt caggtggcaa aacgtcttgc cccacagctg atgaaccgtc
    33601 caccgcaata ttcacgttca gaaagagaaa aagataatga cgccaaccat tgaacttatt
    33661 tgtggccatc gctccattcg ccatttcact gatgaaccca tttccgaagc gcagcgtgag
    33721 gcgattatta acagcgcccg tgcgacgtcc agttccagtt ttttgcagtg cagtagcatt
    33781 attcgcatta ccgacaaagc gttacgtgaa gaactggtga cgctgaccgg cgggcaaaaa
    33841 cacgtagcgc aagcggcgga gttctgggtg ttctgtgccg actttaaccg ccatttacag
    33901 atctgtccgg atgctcagct cggcctggcg gaacaactgt tgctcggtgt cgttgatacg
    33961 gcaatgatgg cgcagaatgc attaatcgca gcggaatcgc tgggattggg cggggtatat
    34021 atcggcggcc tgcgcaataa tattgaagcg gtgacgaaac tgcttaaatt accgcagcat
    34081 gttctgccgc tgtttgggct gtgccttggc tggcctgcgg ataatccgga tcttaagccg
    34141 cgtttaccgg cctccatttt ggtgcatgaa aacagctatc aaccgctgga taaaggcgca
    34201 ctggcgcagt atgacgagca actggcggaa tattacctca cccgtggcag caataatcgc
    34261 cgggatacct ggagcgatca tatccgccga acaatcatta aagaaagccg cccatttatt
    34321 ctggattatt tgcacaaaca gggttgggcg acgcgctaaa accgccacgt cgatgtatga
    34381 tacgcgggct tttgaccagg tctgacagag aggtgcaggg tgaaaattgc catattgtcc
    34441 cgggatggaa cgctctattc gtgtaagcgg ctgcgtgaag ccgctataca gcgcggtcac
    34501 ctggttgaaa ttcttgatcc gctttcttgc tacatgaaca taaatcctgc ggcgtcttct
    34561 attcactaca aaggccgcaa gttaccccat tttgacgcag tgatcccgcg tattggcacc
    34621 gccattacct tttatgggac ggcggcactg cgccagttcg agatgctggg gagctatccg
    34681 ctcaatgagt cggtcgccat tgcccgggcg cgtgacaaat tgcgttccat gcaactgctg
    34741 gcgcgtcagg gcatcgacct gcctgtcacg ggcattgcgc attcgccgga tgataccagc
    34801 gatttaatcg acatggtcgg tggtgcgccg ctggtggtca agttggttga aggcacgcag
    34861 ggaattggcg tcgtgctggc ggagacgcgt caggcggcgg aaagcgtgat tgacgctttc
    34921 cgcggtctga acgcgcatat tctggtgcag gaatatatca aagaggcgca agggtgcgat
    34981 atccgctgtc tggttgttgg cgatgaagtg gtcgctgcga ttgaacggcg ggcgaaagag
    35041 ggcgattttc gttccaattt gcatcgtggc ggcgcggcaa gcgtcgccag tatcacacca
    35101 caggagcgtg aaatcgcgat aaaagccgcg cgaacgatgg cgctggacgt tgctggtgtg
    35161 gatattctgc gtgctaatcg cgggccgttg gtgatggagg tgaatgcgtc gccggggctg
    35221 gaaggaatag aaaaaaccac cggtatcgac atcgcgggta aaatgatccg ctggatcgaa
    35281 cgccacgcta cgacagaata ttgcctgaaa acgggtggtt agtcgcaatc acattactga
    35341 tcatggtttt gcctgcgctt tttgcgtaag ctgtgccggt ctttttatcg aaagaggttg
    35401 tacaaaatta tgacatcgct ggtcgttcct ggtctggata cgctgcgtca atggctcgat
    35461 gacctgggga tgagtttttt tgaatgtgat aactgtcagg ctctgcatct gccccatatg
    35521 cagaatttcg acggtgtctt tgatgccaaa atcgatctga tcgataacac gatcctgttt
    35581 tctgccatgg cggaagtccg accttcagcc gtattgccgc tggcggcgga tttatctgcc
    35641 atcaatgcca gttcgctgac cgtgaaagca tttcttgata tgcaggatga taatctgcca
    35701 aagctggtgg tttgccagtc tttatccgtt atgcagggcg taacctatga gcagtttgca
    35761 tggttcgtgc gtcagagcga agagcagatt tcgatggtca ttcttgaagc taatgcccat
    35821 caactgctgt taccgactga cgatgaaggg caaaacaacg ttaccgaaaa ctattttctc
    35881 cactgataat tcctttcgag cacgcagtcg ctgccgcagt gactgcgcgc tgcaaaatta
    35941 tctgctgttt ttaacctttt cttaaagatt atttcactta tcttgtgtcg atttggcttt
    36001 atcacataga gcaaatacgc ataaaaattt gttaaatacc gttttttaat ccgagctata
    36061 gtctcaaacc ctggctaaag ttattcttgc gatgctttta tatagcgagc agtgctggcc
    36121 gggagagagt tctcttttct tacaccgcgc cgataaaaaa atatgcacgt ttattgcata
    36181 tctttcagtg tgacaacttt tgttcgtttg ttaacgaact ttcagaagga aagagatatg
    36241 accgccttaa ataaaaaatg gctatcgggt ctggttgcgg gtgctctgat ggccgtctct
    36301 gtcggcacgc tcgcggctga acaaaaaaca ctccacattt ataactggtc tgattatatc
    36361 gcccccgaca cggtggctaa ctttgaaaaa gaaaccggta ttaaagtcgt ctacgatgtt
    36421 ttcgactcta acgaagtact ggaaggcaaa ttaatggcgg gtagcaccgg ctttgacctg
    36481 gtggtgccgt cagcaagctt tcttgaacgc cagttgactg cgggagtttt ccagccgctg
    36541 gacaaaagca aattgccgga gtggaagaat ctcgacccgg agctgctgaa gctggtcgcc
    36601 aaacacgatc ccgacaataa atttgctatg ccctatatgt gggcgacgac cgggattggc
    36661 tataacgtcg ataaagtcaa agcggtgctg ggcgaaaacg cgcccgtcga tagctgggac
    36721 ttgatcctca agcctgaaaa tctggaaaaa ctgaaaagct gtggcgtctc tttcctggat
    36781 gcgcctgaag aagtttttgc taccgtgctg aattatctcg gcaaagatcc caacagcact
    36841 aaagcagatg attacaccgg accggcaacc gatctgctgt taaagctgcg cccgaacatt
    36901 cgttatttcc attcatcgca atacattaac gacctggcaa acggcgatat ttgcgtcgct
    36961 atcggctggg caggcgatgt ctggcaggcg tcaaaccgcg cgaaggaagc gaagaatggc
    37021 gtgaatgtct ctttctcgat tccgaaagaa ggggcgatgg cgttctttga tgtcttcgcc
    37081 atgcctgcgg atgccaaaaa caaagacgaa gcctatcagt tcctgaatta cctgctgcgc
    37141 ccggatgtag tagcgcatat ttccgaccat gtgttctatg ccaacgccaa taaagcagcc
    37201 acgccgctgg tgagtgcgga agtccgtgag aacccgggta tttatccgcc tgcggatgtt
    37261 cgtgcgaagc tgttcactct gaaagtgcag gacccgaaaa tcgaccgtgt gcgcacccgc
    37321 gcgtggacca aagtgaagag cggaaaataa tccgcagcct tagatgccgg gcgggcgcac
    37381 cacacccgcc ggcaattcgc accatcatgg tgcgcttgca cacattcaat gccggagagc
    37441 tgccgtgaat gacgctatcc ctcgccccca ggcgaaaacc cgtaaggcgc tgacgccgct
    37501 attagaaatc cgcaacctga ccaaatccta cgatggccaa catgcggtgg atgatgtcag
    37561 cctgaccatc tacaaaggtg aaatcttcgc gctactgggc gcatccggct gtggcaagtc
    37621 cacgctgctg cgtatgctgg caggttttga acaaccttct gccggacaga taatgcttga
    37681 tggcgtcgat ttgtcacagg ttccgcctta cctgcgcccc atcaatatga tgtttcagtc
    37741 ttacgcgctg tttccgcata tgaccgtgga acagaacatc gcttttggcc tgaaacagga
    37801 caaactaccg aaagcggaaa ttgtcagccg ggtcaatgag atgctcggcc tggtgcatat
    37861 gcaggagttc gccaaacgca aaccgcatca gctttccggt ggtcagcgac agcgtgtggc
    37921 cctggcccga agccttgcca agcgcccgaa actattactg ctcgatgagc cgatgggcgc
    37981 gctggataaa aagctgcgtg accggatgca gcttgaagtg gtggatattc tggagcgcgt
    38041 cggtgtgact tgtgtgatgg tcacccacga tcaggaagag gcgatgacca tggcggggcg
    38101 catcgccatt atgaatcgtg ggaaatttgt ccagattggc gaaccagaag agatctacga
    38161 acatccgacc acccgctaca gtgctgaatt tatcggttcg gttaatgtct ttgaaggtgt
    38221 actcaaagag cgtcatgaag atggcctggt gctttattcg ccggggctgg tgcatccact
    38281 gaaagtcgat gtagatgctt cggtggtcga taatgtgccg gtgcatgtgg cgctgcgccc
    38341 ggaaaaaatc atgctttgcg aggaacctcc cgctgacggt tttaactttg cggtaggtga
    38401 ggtgatgcac attgcctatc tcggcgatct ttcggtgtat cacgttcgtc tcaagagcgg
    38461 acagatgatc agcgctcagc tacaaaacgc tcatcgatat cgcaaagggt taccaacctg
    38521 gggcgacgaa gtgcgtttgt gctgggaagt ggacagctgt gtggtgctga cggtttaagg
    38581 agcaaagatg agtacacttg aacctgctgc ccagtcgaaa ccgccgggcg gatttaagct
    38641 gtggttgtcg cagctgcaaa tgaagcatgg gcgcaaactg gtcattgcgt tgccatatat
    38701 ctggttgatc ttgctgtttc tgctgccatt tctgattgtc tttaaaataa gcctggcgga
    38761 gatggcgcgc gctattccac cttataccga actgatggag tgggctgacg ggcaactgtc
    38821 catcactctt aatctcggta attttctgca actgaccgac gatccgctct atttcgatgc
    38881 ttatctccag tcgctacagg tggctgcgat ttcgacattt tgctgtttac tgatcggcta
    38941 tccgctggcg tgggcggtgg cgcacagtaa gccttcgacc cgtaatattt tattactact
    39001 ggtgatcctg ccgtcgtgga cctcgtttct gatccgcgtt tatgcctgga tgggaatatt
    39061 aaaaaacaac ggtgtgctga ataattttct gctgtggctg ggggttatag accagccgct
    39121 gaccattctg cataccaatc tggccgttta tatcggcatt gtttacgctt acgtgccgtt
    39181 tatggtactg ccgatttata ccgcgttgat tcgtattgat tattcgctgg tggaagcagc
    39241 gctggatctc ggtgcacgac cgctgaaaac gttctttact gtgatcgtgc cgctgactaa
    39301 aggtgggatt attgccggat cgatgctggt gtttatcccg gctgtgggcg agtttgtgat
    39361 cccggaactg ctcggtggcc cggacagcat catgatcggg cgcgtgctat ggcaagagtt
    39421 tttcaataac cgcgactggc cggtggcctc ggcggtagcg atcatcatgt tgctgctgct
    39481 aattgtgccg ataatgtggt tccacaaaca ccagcaaaaa agcgtgggag aacacggatg
    39541 aataatttac cggtagttcg ttcaccctgg cggattgtga ttttgctgct gggctttacc
    39601 tttctctacg cgccaatgct gatgctggtt atctattcgt ttaacagctc gaagctggtg
    39661 acggtgtggg ccggctggtc aacgcgctgg tatggtgagt tattgcgcga tgacgcgatg
    39721 atgagtgcgg ttggtttaag cctgacaatt gctgcctgtg cggcaacggc ggcggcgatc
    39781 ctcgggacta ttgcggcggt ggtgctggtg cgctttggca ggtttcgcgg atcaaatggc
    39841 tttgccttta tgatcaccgc gccgctggtg atgccagatg tcatcacggg cttgtcgctg
    39901 ttgttattat tcgtcgcgct tgctcatgcc attggctggc ctgcggaccg cggtatgctc
    39961 accatctggc tggcgcatgt cactttttgt acggcttatg tggcggtcgt tatttcttca
    40021 agattgcggg aactggatcg ctcgatagaa gaagcagcga tggatctcgg tgcgacgccg
    40081 ctgaaagtgt ttttcgtcat tacgctaccg atgatcatgc ccgcgatcat ttctggctgg
    40141 ttactggctt ttactttgtc gcttgatgat ctggtgatcg ccagctttgt ttccgggccg
    40201 ggagccacca cgttaccgat gctggtcttt tccagcgtgc ggatgggggt gaatccggaa
    40261 atcaacgccc ttgcaacgtt aattctcggt gcggtcggaa ttgtcggatt tatcgcctgg
    40321 tatctgatgg ctcgcgcaga aaaacagcgg atacgcgata tccagcgtgc aagacatggc
    40381 tgaagacact aaaatttgcc aacctggcta cataatgccg cgcatgccgc ggcattgttt
    40441 tcatggaaga cgaaacgttg ggatttttta agaaaacatc ttcatctcat gctcgcctga
    40501 atgtgcctgc gctggtgcag gtggcggcgc tcgccattat tatgatccgt ggcctcgacg
    40561 tgctgatgat tttcaatacg ctgggcgtgc gcggtattgg cgagttcatt catcgcagcg
    40621 tacaaacctg gagtttaacg ctggtctttt taagcagtct ggtgctggtt ttcattgaga
    40681 tctggtgtgc gttttcactg gtgaaagggc gtcgctgggc gcgctggcta tatctgctga
    40741 cacaaatcac cgccgcaagt tacttgtggg cggcttcgct ggggtacggt tatccggagc
    40801 tgttcagcat tcccggtgaa tcaaaacgtg aaatcttcca tagcctgatg ctgcagaagc
    40861 tgccggatat gctcatcctg atgctgctgt tcgttccctc gaccagtcgg cggttcttcc
    40921 agttgcaata atgtgtataa tcgtcgcccc tgatgatgtg aaggtcaatg tatgcagtgc
    40981 gcactttacg acgcgggtcg ctgtcgttcc tgtcagtgga taacgcagcc gattccagag
    41041 caactctccg ctaaaaccgc cgatcttaaa aatctgctcg ccgattttcc ggttgaggaa
    41101 tggtgcgcgc cggtgtcagg cccggaacaa gggtttcgta ataaagccaa aatggtggtg
    41161 agtggtagcg ttgaaaaacc actgctcggt atgctgcatc gcgacggcac accagaagac
    41221 ctttgtgact gcccgcttta tcctgcctca tttgcgcccg tttttgcggc gctaaaaccg
    41281 tttatcgccc gtgcggggct gacaccctac aacgtggcgc gtaagcgtgg cgaactgaaa
    41341 tacattctgc tgactgaaag ccagagcgat ggcggcatga tgctgcgctt tgtactgcgt
    41401 tctgaaacca aactggcaca actgcgtaag gcgctgccgt ggttacagga acaactaccg
    41461 caactgaaag ttattaccgt caatattcag ccggtacata tggcgattat ggaaggggag
    41521 acggagatct accttactga acaacaggcg ctggcagagc gttttaatga cgtaccgctg
    41581 tggatccgtc cgcaaagttt cttccagact aatccggcgg tcgccagcca gctgtacgct
    41641 accgcgcgcg actgggtacg gcagctgcca gttaaacata tgtgggatct gttctgcggt
    41701 gtgggtggct ttggtttaca ctgcgcgacg cctgacatgc agttaaccgg gatcgaaatt
    41761 gcatcagagg ccattgcctg tgcaaagcag tcagccgctg aactgggctt aacgcgtttg
    41821 caatttcagg cgctggactc cactcagttt gccaccgctc agggggaggt gccggagctg
    41881 gtgctggtta atccgccgcg ccgcggcatt ggtaaaccgc tatgtgatta tctctcaacg
    41941 atggcaccgc gttttattat ctactccagc tgtaacgccc aaaccatggc gaaagatatc
    42001 cgcgaactgc caggttaccg catcgaacgg gtacagcttt ttgatatgtt cccgcacacc
    42061 gcgcactatg aagtgatgac gctgctggtg aagcaataaa aaagccgcag gtgcggcttc
    42121 agattgctga tcaggtgcgc tttgttcatg ccggatgcgg cgtgtacgcc ttatccggcc
    42181 tacaaaatca tgctaaatca atacattgca gagttgatgt gggccagata agcgcagcgc
    42241 atcaggcaat cttacttttg tcatcagtct caattactgc gggaaccact ggtcattgat
    42301 tttctgatat gtaccgtcag ctttaattgc tgccagcgcg ttattcagtt tttccagcag
    42361 agctttgtta tccggacgta cagcgatacc caggccggtg ccgaagtatt gcggatcggt
    42421 cactttttca gtcgcaacgc ccagttgcgg attggttttc agccattcgt ttaccaccgc
    42481 tgtgtcacca aataccccat caatacgacc atttttcaga tcgataaagg cattctgata
    42541 actgtcatag gagacagttt tcacttcggg gtgctgatcc tgaatatatt tctggtgcgt
    42601 ggtgccgttt tccatcccaa tacgtttgcc tttcagatcg gcaaacgttt tgtaggtatc
    42661 ttttttggca atcacgacgg ctgagttttc atagtagggc gtggtaaacg atacctgctt
    42721 gctacgctcg ggcgtgatat ccataccgga gattacggcg tcatattttc tgaatttcag
    42781 tgacgggatc aggctgtcga acgcgtgatt agtaaaagta cattctgcct gcatttgttt
    42841 gcacaaggct tttgccagat cgatatcaaa gccgacaatc tcattattag cacctataga
    42901 ttcaaagggt ggataggtgg ctgaaacgcc aaaattgatt ttctctgcgg cagaagcacc
    42961 gaaagtaaag gaagcaagta aagcggcaag aactaacttt ttcatgatgg aactcccgtc
    43021 tgtcaatctt atgatttttg gccgtgtctg cggcatggga taacaatgcc atcaagtgaa
    43081 tttatatgca ataaatatga ttaaataatt taaatgaaat aaaaaaagac ggataactta
    43141 gtgagttgtc cgtcttcatt ataagaattt atgcactatg taggccggat aaggcgtcca
    43201 cgccgcatcc ggcacaggca ctgtgctgat gtctgatgcg acgctggcgc gtcttatcag
    43261 acctacaaac ccccccggcg aatgtacgca gctacattaa ttccgccgtt cgaatgccag
    43321 tgctttgcgc tcgatcagac gcatcatcag cgtcagcagg ccgttgacga ccaggtaaat
    43381 aatccctgcc gcaccgaaca ccattacatc gtaggtgcgt ccgtacaaca actggctgta
    43441 tcccatcact tccatcagcg taatggtgta agccagagag gtacttttga acaccagcac
    43501 cacttcgttg gaataagaag agagcgagcg tttaaaggca tacggcagca ggatcgccag
    43561 cgtatctttt ttgctcattc ccagggcgct acaggactgc cactgacctt ctgggatcgc
    43621 acgaattgca ccgtaaaaca gctgcgtggt atacgccgca ctgttcagcg ataacgcaat
    43681 cagcgcacat aaccacggtt ctgacaacaa atgccacagt gccggatact cctgcaaagt
    43741 cggaaactgg cccggcccgt aataaatcag gaagatctgc accagcagcg gcgtaccggt
    43801 aaacagcgtg atataacccc gcaccagcca caccagcacc ggcgttttca gcgtcaggat
    43861 gatggtaaaa atcaatgcca gaatcagtgc cacaatcagc gaggcaacgg ttagcgtcag
    43921 gctggtgtgt agccctttca tcagttcggg taaatactca aacattagct gggcctccgc
    43981 tcaaaacgtg tcgcgcgcag gtcaatgcgt ttgagaatgt actgactgag cagggtgatc
    44041 accaggtaaa tcgccgccgc cacaatgtac caggtaaatg gttcctgggt acgagtagcg
    44101 atgctttttg tttgcagcat taaatcattc acactaatca aactgaccag cgcggtatct
    44161 ttcagcagca ccagccactg gttaccgagg ccaggcagcg catgacgcca catctgcggc
    44221 atcaccagac ggaaaaagat agccgatttc gacagcccca gcgcctgacc agactcccac
    44281 tgacccaccg gcaccgcttt caacgcgccc cgaagcgttt gcgaggcata ggcggcatac
    44341 agcagtgaca gagcgatgac accacaaagg aacgggctaa cgtcgaagtt ctcaatgtcc
    44401 atctgcactg ggatctgcac gaacccaaga ttgatagtga agccatccga aagcgtcagc
    44461 agcagctgcg aggagccaaa atagataaac agcaccacca gaatttctgg caggccacgc
    44521 agaatggtta ccagcgctga acctgcccac gcgacaggac gccattttgc cgactcccat
    44581 accgcaaaga acatcgccag cgccagcccg acaatcaatg cacaaacggc aaggccgacg
    44641 gtcatcccgg cggcgcttgc taaaggaaaa aattcattca tcaggaatta cttctggaac
    44701 catttgttgt agatggtttc gtaagtgcca tctttcttca ctttttccag cgcagtgttg
    44761 agtttctgct gcagctcagt gttgccctga cgtaccgcga tgccgaggcc agtgccgaag
    44821 taatctttat cggtcacttt gtcgcccacc gccgccagtt tcgggttatc tttcagccac
    44881 tcagtgacca ctgcggtgtc accgaagacg ccgtcgatac gcccgttttg cagatccagt
    44941 tttgcgttct ggtagctgtc atacggaacg gtagtgattt ccgggtgctt atccataatg
    45001 aatttctggt gtgtcgtccc gttctgaacg ccgacttttt tgcctttcat ctgatcaaca
    45061 ctggtgtatt tgccttgctg acccacaaac agggcagagt tgtcatagta cggggtggta
    45121 aacagtacct gcttttcacg ctccggagtg atatccatgc ccgccatcac tgcttctacg
    45181 cgacggaatt tcaggcttgg gatcaggctg tcaaacgcct ggttagagaa agtacaggtt
    45241 gcatcaatct ctttacacag tgcctgtgcc aggtcgacgt caaaaccaac gatctggttg
    45301 tttgcatcaa tcgattcaaa cggaggatag gaggcttcgg tagcaaaacg aatggtttcg
    45361 gcagctgtgg cggaaagact aaaacctgca attaacgcgg caatcagaac ttttttcatt
    45421 gttgttatcc cgaatcttag tgagagagat agtttttaaa tgcttcggtt tgcggctcgg
    45481 taaagcagct cgcgtcgcct tgttctacga tatgaccatt ttccatatac accactcggc
    45541 tggcggtttt acgcgccact tcaacttcgt gggtgacgat cacctgggta atattcgttt
    45601 ctgccagctc acgaatgatg ctgacgattt gtgccgtaat ttccgggtcc agtgcggcgg
    45661 tcggttcatc gaacagcagt acctgcggtt ccatcatcaa cgcacgggca atagcaacac
    45721 gctgctgctg accaccagaa agatgcagcg ggtaacgatc gctataaggt ttgagacgca
    45781 gacgttccag cagtttttct gcacgggcca gcgcctgatc tttactcaac cccagtacac
    45841 ggcagggcgc ttcaatcagg ttttgctgca cggtcagatg cggccacagg ttgtattgct
    45901 gaaacaccat gccaacgtta cgacgcaaat cgcgaatcgc tttgtcagag ggtgttttgg
    45961 tgaaatcgaa atggttgcct gcaatgttga gcgtaccgga gcgcggcatc tcaagcagat
    46021 tgagtacacg cagcagcgag cttttacccg cgccgctggg gccaagtaac accagcgttt
    46081 cgccctgtgg gcaatccagc gtgatatcga acagcgcctg atgcgcgccg tagaagcaat
    46141 taatgccgtt taattgaata ctcattgaca ctcgtatact ggcagtctga tagctattga
    46201 ggtcgaagat agtacctttg acagaataat tatgcaatat ttctgcttta aaagttaaaa
    46261 gcaaagcgca ttattcaata aacatagcac aaaataacgg gggcggtggt cggcgagcat
    46321 aaatgtcggc attcctcacg aaatgccgga caatttacgg ggtttattgg ttgatcaagg
    46381 cgttagcgat tctcgatgga ctgacggagc gtacccgccg tggcatgaac gctgccgcct
    46441 aaatagcgta catcgtcgat cacccaacac tggccttcct gaatcattaa cacttcatcc
    46501 tgccagctct gatcaccctg ttttagatcc acacgcagag gaatatttcg cgcatcacga
    46561 ttcgggattg ttgaggcact ggcaacacgg gcgctctctg gcaaggttgt gcgactggag
    46621 aatggatcgt tggtcagtag ttcccgatgg ttattatccc gggaggcatc gctaagcagt
    46681 gtcgccagtt tgtcgctcag ataagggcgc aaggcggtga tgtcgttgct gcggtgcaaa
    46741 atgcggtagt cataaaattg ctgggccacg ttatccgggc ctccttcaac gcaaggacca
    46801 ctgcgtgtgc cgttatcttt ataagctgga gtgactgtgg tgcaggcact gaggagcagt
    46861 gcgcagggga taagcattgt caatttgctg tagcgcataa tgatttcctt ataagcgatc
    46921 gctctgaaag cgttctacga taataatgat atcctttcaa taatagcgta tcagtctgat
    46981 aatgcttttg agatcgaagg cttagcaaac aaggagatcg atcatgcaat tttctacaac
    47041 cccaactctg gaaggccaga ccatcgttga atattgcggt gtggtgaccg gcgaagcgat
    47101 tttaggtgcc aatattttcc gtgatttctt tgctggtatc cgcgatatcg ttggcggacg
    47161 ctccggtgcc tacgaaaaag aattacgtaa agcgcgggag atcgcctttg aggagctcgg
    47221 ctcccaggcg cgggcgctgg gggccgatgc cgtagtcggt attgatatcg actacgaaac
    47281 ggttgggcaa aacggcagta tgctgatggt tagcgtcagc ggtacggcgg tgaaaacgcg
    47341 tcgatgagaa gagtcttctg gctgattgcc gccgctctgt tactggcagg gtgtgcaggc
    47401 gaaaaaggca ttgtcgagaa agagggatat cagcttgata cccgacgcca ggcgcaggcg
    47461 gcgtatccgc gcattaaagt gctggtgatc cactacaccg cagatgattt tgatagctcg
    47521 ctggcgacac tgaccgataa gcaggtcagc tcgcattatc tggtccctgc ggtaccaccg
    47581 cgatacaacg gtaaaccgcg catctggcaa ctggtgccgg aacaagaact ggcctggcat
    47641 gcggggatta gcgcctggcg cggggcaacg cgccttaacg acacctctat tggcattgag
    47701 ctggaaaacc gtggctggca aaaatcggcc ggagtgaaat attttgcccc gtttgaaccg
    47761 gcacagattc aggcgcttat tccactggcg aaagatatta ttgcccgtta tcacatcaag
    47821 ccggaaaacg tagtggcaca tgcggatatc gcaccgcagc gcaaagacga tccggggcca
    47881 ttatttccct ggcagcaact ggcgcagcag gggattggtg cctggccgga tgcgcagcgg
    47941 gttaactttt accttgccgg gcgcgcgccg cacacaccgg tagataccgc gtcattgctg
    48001 gagcttttgg cgcgctacgg ttatgacgtt aaacctgata tgacaccgcg cgagcagcgg
    48061 cgcgtgatta tggcattcca gatgcatttc cgcccgacgt tatataacgg cgaagcggat
    48121 gcagaaactc aggcgattgc cgaagcattg ctggaaaaat acgggcagga ttagcgcggc
    48181 agttttccgt ggtcgcgtag ccaggcggca gttttctcga taccttcatc cagggtgatg
    48241 accggctgat aacctaactc ttcctgcgca cgcgtaatat ccagcgtaaa gtcaaaattc
    48301 aacttggaga cgccgtagtg ggtcagcggc ggctcttttg ctgacttgcg gcctaaacgc
    48361 tccatgctgc gggcgatcat atccagcatc gggtagggga cggaacgaat acgacagtca
    48421 atattcaact cgtcgatcag cttctgcacg atgctgcgca gtgtgcgatg ctcgccgttg
    48481 gtgatgttgt acacacgccc ggaaggtagc ttatcgcagg cttcctggct tgccagccac
    48541 atggcgtgca cggcattttc atagtaggtc atatcgacca gcgcactgcc gccatgcggt
    48601 aacagaatac tgccgtagtg gtgcatcata tgcgccagac ggggaataaa gactttatcg
    48661 tgcggtccga acagactttg tgggcgcaga atagtaaagc gcgtttgtgg attcgcctgc
    48721 gaaagcatat tgatcacttc ttcgctggct gctttgctgc gggcaaactc gttggcgaag
    48781 cggtgagggc gaaaatcttc tttaatatcg cgatggtggt gataatcgaa gtacagggag
    48841 ggggaagaga tatgaataaa gttacgcaca ccccaggcga cagcccattc acccaggcgg
    48901 cgagtggcgc gaacgttagc cagatcgaaa gcctgttgtg tcccccaggg tgaggtaaag
    48961 ctggagcagt gccacagcgt atcaatgccc gcgagcatca ctttagcttg tgatgaaacc
    49021 agctcggtca gatccgccgg aacaaactct gcgcccattt tttccagcaa tttgcccatt
    49081 gcctcgttgc gaccggtcgc tcgcacgctg atgcctttct ggcataaaaa ctctaccgcg
    49141 tttcgaccta agccgctggt ggcgccggta accagtacct tcatatcaat ccactgttgt
    49201 tgagaaaata acgtgcgcat tcttccgtga tttcccccat gatgcaatgg gaaacatgaa
    49261 agaataacgc aggttttgtc gattaatctg tgctttgttc tgccagtctg gcgatttgtt
    49321 ttgccattcc gcgaaaaata aacagatgcg cggggatcat caataaccag taaaacagcc
    49381 ccggcatacc gtgcggatgc cagaaagcgc ggacatcgat agtacgatag tcgcctttat
    49441 cttccaggct aaaacacagt cgtcccagcc ccggcgcttt catgccaaat aacaacgtaa
    49501 gttgtttttc cggttcaacg acaatcactt tccagctatc taccgcatcg ccagtctgta
    49561 aatattcgcg ctccgggcgg cctttcgcca gcttatgacc gatcgcgcgg tccatcaacg
    49621 cccgtgtctg ccacaaaata ttgccaaaga aataacgctc tttaccgccg atttggttca
    49681 ctacctgcca taaagcagca aggctggcgg acgttttaac ggtaaacccc gcctgtttgg
    49741 caaaataacc gtactccggt cgccagcggg caaaggcctg agcgtcgtag ccccagtcgc
    49801 tggagttgac cagtttttcc tcctctttca acgtgctacg taccgcgtca tcgaaagcga
    49861 tcagccgttg tgggatgagt gcacgtagcg cggtatcatc cgccagcaga tcgtgtttca
    49921 gcccctgaat caacgccctg gcggtggtgg gcggtacgga agtaatcaca ttgagaaacc
    49981 acaccgaaat ccagcgggtg gggaggggga tggggatcaa ccagcggcgc ttaccgctca
    50041 ccgccataaa atgttcaaac tgttgctgat aactgagcac ctctggtccg gcggcttcga
    50101 agatgcggtg ttcgctggcc ggatgatcta acaacgccac cagatagtgc agcaagtttt
    50161 ccagcgcgat gggcgtggtg cgtgaacgta cccagcgtgg cggcgttaac actggcaggt
    50221 tgtagaccat atcgcgcatg acttcgaacg ccgctgaacc tgcgccaacg ataattccgg
    50281 cccgaagttc ggtcacaggt acattcgctt cacgaagaat gtccgccgta gcctgacgag
    50341 cacgcagatg atccgactgc tcatgtggcg gggcctgcaa cgaactgaga aagattaatt
    50401 gcttaactgg tacttcacgt agcgcatcgc ggacgttgag agccacctgg cgctcctgag
    50461 cgataaaatc gccgccttcg cccatgctgt gcaccagaaa atagacggta tcgatatcct
    50521 gcaacagggc cggaaggtta tccggccagc tgagatcgac tttatggcaa ctgacgtttg
    50581 ccagttgcag ctttgcaagc ctgtcgacat gacgtgccgc cgccaggatc tgatgccctt
    50641 gctggctgag tgtgcgcacc agatgctgac caatgtagcc actggcaccg agaactaaaa
    50701 tgcgttgcgg cacgtctctc tccttaacgc gccaggaatg cgcgccagtg ggcggcgact
    50761 tccgccagtt gttcgcgcga gacgtcaaga tgcgtcacca ggcggacaat cggcgaggcg
    50821 ttaatcagca cgtttctcgc tttcatgtat tcgcctaacg cggcagcatt ttcttccccg
    50881 acgcgaacaa acagcatatt agtgtcctga cgcatcacat ccgcgcctgc ttcacgcagt
    50941 tgctccgcca tccaggcggc gttgtcgtga tcttcctgca accgtgcgac gttatttttc
    51001 agggcataca tcccggcggc agccagaatc ccggactgac gcatcccgcc accggccatt
    51061 ttccgccagc ggatggcacg tttaatgtaa tcacgattac cgacgagtaa tgaaccgact
    51121 ggcgtcccaa gacctttcga caggcaaatg gtgaacgaat cacaatattg cgtgatctct
    51181 ttcagttcgc agccgtaagc caccacggca ttaaagatgc gcgcaccgtc aacatgcagc
    51241 gccagattgc gctcgcgggt aaattcccat gcttctttca ggtattcacg cggcagcact
    51301 ttgccgttgt gggtgttttc cagactgagt aatttggtgc gggcgaaatg gatatcgtcg
    51361 ggtttgattt tcatcgccac tttatccagc ggtagcgtgc cgtcggcagc cgcgtcgatg
    51421 ggttgcggct gaatactgcc cagcaccgct gcgccaccgg cttcaaacag atagttatgc
    51481 gcggcctgac cgacaatata ctcttcgcca cgttcgcagt gactgagcag agcgaccagg
    51541 ttggcctgag tgccggtagg cagaaaaatg gcggcttctt taccggaaag ctctgctgca
    51601 tagtcctgca gagcattaac ggtagggtcg tctccgtaaa cgtcgtcccc aaccggggcg
    51661 gccatcatcg cttcgagcat ggcgcggctc ggtcgggtaa cggtatcact gcgtaaatca
    51721 atcatggcat gtccttatta tgacgggaaa tgccaccctt tttaccttag ccagttcgtt
    51781 ttcgccagtt cgatcacttc atcgccgcgt ccgctgataa ttgcgcgcaa catatacagg
    51841 ctaaaacctt tggcctgttc gagtttgatc tgcggtggaa tggctaactc ttctttggcg
    51901 accaccacat ccaccaacac cggaccgtcg atagagaagg cgcgttgcag ggcttcatca
    51961 acttcagacg ctttttctac acggataccc gtaatgccgc acgcttcggc aatgcgggca
    52021 aagtttgtgt cgtgtagttc ggtgccgtca gtcaaatagc caccagcttt catctccatc
    52081 gccacaaagc ccagcacgct gttgttaaag acgacaattt tcactggcag tttcatctgc
    52141 actactgaga ggaaatcgcc catcaacatg ctaaaaccgc catcgccgca catggcgacc
    52201 acctgacgtt ctggctctgt cgcctgcgca cccagcgcct gcggcatggc gttagccatc
    52261 gaaccgtggt taaacgaacc taacaggcga cgcttgccgt tcattttcag ataacgtgcc
    52321 gcccataccg ttggcgtgcc gacgtcacag gtaaagatgg cgtcatcggc ggcaaaatga
    52381 ctaatttgct gcgccagata ttgcgggtga atggctttct cgctcggttt agctaaatcg
    52441 tccagccctt tgcgggcatc gcggtaatct tccagcgctt tatccagaaa cttgcgatcg
    52501 gttttttctt ccaccagtgg cagcaatgcg cgcagggttg atttgatatc gccgaccagc
    52561 gccatatcta ccttgctatg cgcgccgatg ctggctggat tgatatcaat ctgaataatt
    52621 ttggcatcgg tcgggtagaa cgcacggtag gggaactgag taccgagtag cactaacgtg
    52681 tcggcgttca tcatggtatg gaaacctgac gagaagccga ttaacccggt cattccaaca
    52741 tcatacggat tatcgtattc gacatgttct ttaccgcgca gggcatgaac aataggcgct
    52801 ttaattttcc cggcaaactc aactaactct ttatgcgccc ccgcgcagcc gctgccacac
    52861 atcagggcga tattgctgga ataacgcagc agttgcgcca gtttgcgtaa ctcttcttct
    52921 tccggcgtca cgattggttg tggcgcatga taccagtgcg tggttgcccc ttctggcgca
    52981 ggttttaacg ccacgtcgcc tggtaacacg acaaccgaaa cgccacggtt aagcaccgct
    53041 ttgcgcatgg caatcgccag tacttgtgga atctgctccg ggctggaaac cagctcgcaa
    53101 tagtgactac attcgcggaa tagctcttgt gggtgggttt cctggaaata gccgctgcca
    53161 atttcgctgg agggaatatg agcggcaatc gccagtaccg gaacgtgatt gcggtggcaa
    53221 tcgaacaggc cgttgattaa gtgcaggttg ccggggccgc acgatccggc acagaccgcc
    53281 agttctccgc taagttgtgc ttcagcgcca gcggcaaagg ccgccacttc ttcgtggcgg
    53341 gtggacatcc actcgatggt gcccatgcga ttaagactgt cactaagacc gttcagagag
    53401 tcgcctgtga ctccccagat gcgtttcacc cctgccgatt cgagtgtttt ggcgatataa
    53461 gctgcaaccg tttgtttcat ggttctccat ctcctgaatg tgataacggt aacaagttta
    53521 gttcatctga cggaggggga agggatggga gagaaaggag gcactaacgg ttaaatagcc
    53581 cgatgaaagg aatatcatcg ggcataaggc gattatgcga gaaccaaatc cccctgcgga
    53641 tggcaggagc aggccagtac gtaaccttca gcgatttcgg cgtcggtcag cgtcattgta
    53701 ctgctcaccg tatattcacc ggaaaccact tttgtcttac agcagccgca aacacccgca
    53761 cggcaggcag cgacaaccgg aacgttattg ctttccagcg cctccagtag cgtggtgcca
    53821 accggggcgt aaaattctcg tgccggttgc agtttggtga atttcagacc gctggtcgcc
    53881 gcttctgcta ctggggtgaa gaatttctct ttaaagaaac gcgtcacgcc gagcgctttc
    53941 acttcctgct ctacccaatc catatacgga gccgggccgc aggtcatcac ggtacgtgaa
    54001 gctaagtcag gtacacctgc cagcagttcg cgagtgagac gaccagcgat aaagccttcg
    54061 gtaacgttat tttctgccac cagcgttacc ggatagttac gccactcatc ggcgaaaata
    54121 acatcctgcg gcgtacgcac gttgtagatc acccgcacat cggcctgtgg acggttcttc
    54181 gcaagccagc gacgcatcga cataatcggc gtgacgccgc agcctgccgc cagcaacagg
    54241 aatttatctt ctgctttatc gtcgcaggta aattccccca tcgcgtccga aagccagaga
    54301 taatcaccgc gttttacatc gcgcgtcagc cactgggagc cgacaccgtc atcaatccgc
    54361 cgcacggtca gggtgatata ttcactcacg cctggcgtgg aggaaatggt gtaagcacgc
    54421 agcgtttccg ctgagtttcg cacgctgacc agtgcatatt gcccggcgcg atatgggtag
    54481 taatcgtggc aaatcaggga aatcgtccac acatccggcg tttcttgcgt aatgtgatga
    54541 acctgcatcc gccacgggca ttgattcgtt ggcatcgtca tcgacaaact ccttacgcgc
    54601 tcaacagttg cttcatgtct tcttcaacag tggtgataga acgcaggcca aatttctcgt
    54661 tcagcaccgc cagcaggtct ggtgtcagga aaccaggtgc agtcgggccg gtgacgatat
    54721 ttttcacgcc cagagaaagc agcgtcagca gaatgacgat cgctttctgt tcaaaccagg
    54781 agagcaccag cgacagcggc agatcgttga caccgcagcc cagtttctct gccagagtga
    54841 cagccagaat aatcgctgag taagcatcgt tacattgacc tgcatctacc agacgcggca
    54901 gaccttcgat atcgccaaac tcaagtttgt taaagcgata tttaccacag gcgagggtca
    54961 ggatcaggca gtcatccggc acgctggtgg cgaaatcggt gaagtagtgg cgctcgccgc
    55021 gtgcgccgtc acagccacca agcaggaaga tatgacgcag tttttcacgg ctcaccagat
    55081 caatcagcgt atccgctgcg ccaagcagcg tctggcggcc aaagcccacg gtgatcaggt
    55141 gcggaatttc gctgtacggg aagcccgcca tttgttgcgc ctgggcgatg accgcagaaa
    55201 aatcttcgcc atccagatga cgcacacccg gccagccaac gatgctgcgg gtccagatac
    55261 gatcgtcata agcgcctacg gttgggtcga tgatgcagtt cgaggtcatc acgatggggc
    55321 cagggaaacg agcgaactcc acttgctgat tctgccagcc gctgccgtag ttaccgacca
    55381 gatgcttgaa tttacgcagc tccgggtagc catgcgcagg cagcatttcg ccgtgggtgt
    55441 aaacattaac gcccgtgcct tcggtctgtt ccagcaggtt gtagagatct ttgagatcgt
    55501 gaccggaaat caggatgcat ttacccgccg tcgctttgac gttgacctgg gttggcgtcg
    55561 ggtgaccgta tttaccggtt tcgcctgcat ccagaatgct catcactttg aagttcatct
    55621 ggccgatttc cattgaacac tcaagaagcg cgttcatatc ggcaggccag gtccccagcc
    55681 acgccatgat tttatgatac tgggcataaa tatcgttgtc gtattgaccg agaacatgcg
    55741 cgtgttccat ataggccgct gcacctttca ggccatacag gcacagcaga cgcaggccga
    55801 gaatgttttc gccaatcgcc gctttatctt tgttaggggt aaattctgct gcctgacgtt
    55861 gcagctcgcc gagatcgtcg ctcaccagtt gcaggtcagc catcgggtta tcgacgcgcg
    55921 cgttggcatc tacagccagg cattgcgctt tcagcgcctc gcgcagggca atcgcttcac
    55981 gagcgtagcc gacaatacgc ggagaatcga agttaacgtt ggtcagggtt gagaaaaagg
    56041 cacgtggcgc gaagctgtca acatcgtggt tgatgatgcc gtattcacgc gcttttaccg
    56101 cccaggcaga aagcccttgc agcgccgcga tgagtaaatc ctgaaggtca gaagtttccg
    56161 ccgttttacc acacatcccc tgcgcgtatg agcagccgtt tcctgccgga gtacggatag
    56221 tttgttcaca ttgcacacaa aacatgatca caccttttaa agttatattt aatatacatg
    56281 tttaaggtta agacgcttaa cgcggggata aaagggattt ttcatgcaac tttaagggag
    56341 attgatttag cgcaattttg gcggcaggga tctaccgcca gagaggtatt acgcagagaa
    56401 aaaggcgatg aggatcggca ctaacaggct aagaataaaa ccgtgaacaa ttgccgccgg
    56461 gaccatatcc agcccgccag tacgttgaag aacgggcagg gtgaaatcca ttgatgtggc
    56521 accgcataag cccagtgcag tagagcggct gcggcgaatc agcccaggga tcaacataat
    56581 agcaatcagt tcacgggcca gatcattaaa aaacgccgcg ctcccgatta ccggaccaaa
    56641 agattcggtc aataaaatac cggaaagaga ataccagccg aaaccggagg ccattgccag
    56701 cgcggtattg atggggagat caagaataaa ggcgttaatt aaaccaccaa ttaatgaact
    56761 gacaaccacc accacggcga caatcattcc ccggcgatta aggacaatct gctttaaggt
    56821 catgccatta ttgcgcaact gaataccaac gaggaaaagt agcaaaatta acgtgtattc
    56881 actggcttcg gtcgcgtgtt gtaagaaagc cagtccactc agaccaatgg caaaaccaat
    56941 cactactacg ccgcacagtt ttagcgactc cagcgccatc gcaatacgcg acgggagttt
    57001 ttcttgctga tggtggttgc gccacggcag gcctcgctcc agccacatca gggcggcaat
    57061 attacacagt aaaataacgg taatactgac ggcagaataa tgcagaatcg ccaacaggtt
    57121 actggcgagg ttatcgagaa acgccagact gatacccata aaaaagagaa taaggtaaac
    57181 catccagctt aatagctgat taataacttt taacgcagct tgttggcgaa gcggaatgag
    57241 gtaacccaca atcaggggaa ccagaatgat taacagccca gaaaacatga aaacccagtc
    57301 cttgcaaaga tgaagtcgaa atgcgcgatg acacactact gaaagcggaa ggacgagtaa
    57361 agttgcaatt aaaaggaaat gttatgcata aggagcagta gagtattcgt tttcatttaa
    57421 agatattctt gcgctttaat tacaaactgc accgatgttg gtggcgtcaa aatcgccgag
    57481 gcgttccctg aaggccgggg cagcccacat ggatgtgggc tgagggcgcg ttttacaggg
    57541 atgttacctc gcgcccgacc cggtagccgt aagggataag tcgagggcac cgcgcagcgg
    57601 cgattttgtt cgccagagcc cgggggtgca gggggcggcg gcgattggcc gccctgcgcg
    57661 ctccttgcgc cagtggcaat atgtggctta gctcatgaaa ggagcgcaac aagatgatga
    57721 atcaacatat aacaacatct taaaaaaagg cctgacatta cgccaggcct tctgcgttaa
    57781 ttaatcacgc ttttccagca gggtccggta aatcagacca ccgataatgc cgccgacaat
    57841 tggcaccacc cagaagaacc acagttgttc taatgcccag ccgccctgga agatagcaac
    57901 cgcggtgctg cgcgccgggt taacagaagt gttagtcacc ggaatactaa ttaagtgaat
    57961 cagggttaag gccagaccaa tagcgatcgg cgcaaaacct gccggcgcga atttgtcggt
    58021 tgtgccgtgg atcaccaaca ggaaacctgc actcaatacc agttcaacta ccagcgcgga
    58081 aagcatggaa taaccgcctg gtgaatgctc gccataaccg ttagaagcaa aaccgctggc
    58141 tgccgcgtca aaacccgttt taccactggc aattaaatac agcagcgccg ctgcaacaat
    58201 accgccgaca acctgggcaa ttacgtagcc aacgacttct tttgccggaa aacgtccgcc
    58261 agcccataaa ccaatagtga ccgccgggtt aaaatgacca ccagaaatat gaccaacagc
    58321 aaaggccatc gtcagaacgg tcagaccgaa cgccaacgcc acgccggcaa aaccaatgcc
    58381 taattccggg aagcctgcgg ccagtacagc actaccacag ccaccaaaaa caagccagaa
    58441 agtaccaaaa cattcagctg ctaattttct gaacatatcc acctcaatta aaaattgacc
    58501 ctgtgaaaaa tatggtcgtt ttatagggtc gtcgtaaaaa agtgacgacg gaaataatgc
    58561 gcggctattt taaaaacgaa ggcgagtcat tcaccagata aataaatcca gtaaatttga
    58621 tttagggcaa cagcgggttg ccccatatag tcatttgtct gattgacagt gtagtgcaag
    58681 caaaagattt aatcctttag gcgtaataaa aaataattta tcatgctaat tatttgattt
    58741 tgttgttttt gcagacttat cagcaagagg gagtataacg cgattattcg ctcatttttc
    58801 agacatttgc catgcttaaa tgtgatgtca tcacgtatta gcaaggcctt tcccgttata
    58861 ctgccagcgt aaaggataag tcacatattt ctggagggga tatgattctt gagcgcgttg
    58921 aaattgtggg ttttcgcggt atcaaccgtt tgtcgttgat gctcgaacaa aacaacgtcc
    58981 tgattgggga gaacgcgtgg ggtaaatcca gcttgctgga cgccttaacc ctgctgctat
    59041 cgccagaatc agatctctac cattttgagc gcgacgattt ctggttcccg ccgggagata
    59101 tcaacgggcg agaacatcat ctgcatatta ttttgacctt ccgcgaatcg ctgccaggcc
    59161 gacatcgggt tcgccgttat cggccgctgg aagcgtgctg gacgccatgc accgatggct
    59221 atcaccgtat tttttatcgt ctggaagggg agagtgcgga agacggcagc gtgatgacac
    59281 tgcgcagttt tctcgataaa gacggacatc cgattgatgt cgaggatatt aacgatcagg
    59341 cacgccatct ggtgcgttta atgccggtgc tgcgcttgcg tgatgcccgt tttatgcgcc
    59401 gtattcgtaa cggcacggtg ccaaatgttc ccaatgtgga agtcaccgcg cgccagctcg
    59461 atttcctcgc ccgtgagttg tcctcacatc cgcaaaatct ctctgatgga cagattcgtc
    59521 agggactttc cgcaatggtg cagttgcttg agcattattt ctctgagcag ggggccggac
    59581 aggcgcgata tcgtttaatg cggcggcggg ccagcaatga gcaacgaagc tggcgctatc
    59641 tggacatcat caaccggatg attgaccgac ctggagggcg ctcgtatcgg gttattttgc
    59701 tcggcctgtt tgctacttta ttgcaggcaa aaggcacatt gagactggat aaagacgcgc
    59761 gtccattgtt gctgatcgaa gatccagaaa cccgtttaca ccccattatg ctttcagttg
    59821 cctggcatct gttgaatctt ctgccattgc agcgcattgc caccaccaac tcgggtgagt
    59881 tgctttcgtt aacgccggta gagcatgttt gccgactggt acgtgagtcc tcgcgcgttg
    59941 ccgcctggcg tctggggccg agtggcttga gtaccgaaga tagccgacgc atatcctttc
    60001 acattcgttt taaccgtccg tcatcgctgt ttgctcgctg ctggttgctg gtggaagggg
    60061 aaacggaaac ctgggttatc aatgaactgg cgcgtcagtg cggacatcat tttgatgccg
    60121 aagggatcaa ggtcattgag tttgcccagt ccgggctaaa gccactggtt aaatttgccc
    60181 gccgaatggg gattgaatgg catgtactgg tcgatggcga tgaagcaggg aagaaatatg
    60241 ccgctacggt acgcagcctg ttgaataacg atcgggaagc cgaacgagaa catttaacgg
    60301 cgttaccggc gctggatatg gaacatttta tgtatcgcca gggattttcc gatgtgttcc
    60361 accgcgtggc gcaaatcccg gaaaatgtac cgatgaatct gcgcaaaatt atctcgaaag
    60421 cgatccatcg ctcttccaaa cccgatcttg ccattgaagt ggcaatggag gccggacgtc
    60481 gtggtgtgga ctccgtaccg acgctgctga aaaaaatgtt ctcacgcgtg ctgtggctgg
    60541 cgcgcggtcg cgcggattaa ccgcgaaaca tcgtggccat ttgtggctga atagcgtcga
    60601 gcatctcata gcgccgacgg tattcagccc gttttttact ggcgatttcg gcaatctctt
    60661 ttcgtgctat ctgtgctgga aggcggtaat ggcgttcagc atcacatacg ccgccaaccg
    60721 attcccagaa agcgttgtaa tcggcatgga tcttgccttc tttatcacga taacgcaggc
    60781 tgcggtaaat atgcgtttca ttgctgacgg caataatctg ctctacctgc aaacgttggg
    60841 caaacagaca ggccgcttcc atcacgaggc gtttgggaaa tagcccgtgg caggctttcg
    60901 tcgcattctg gatttcctga tgtggaattt cccattttgc gccttgcagt ccgccaataa
    60961 acatcgttct tttcccctga tattcacaca gggtaaacgt gatctctgcc agaggaatac
    61021 cttcgctgtt gcgaaacagg attgtgctgt caccttcttt atccattgag atcatcatgg
    61081 tcagctcaag cgtgaactgc tcgccgtttt tgccttccag cttcgccagt tgcagcccgg
    61141 gggtattcaa atataagctg aattcttccg ccgacataca tccgcggagt aacgcataat
    61201 ggtaacgtaa cgcctccagc aattgcttac ggctaagatt cgccgcaagg taagggcgat
    61261 gcagacgcac aggcagtcgc ggttggcgcg ttaacaacac attgagatta ggccagtggg
    61321 aaagttcgtt catccactca acgcttaaac gcggcataat caacgagcgc agcaaaaatt
    61381 tctggcgaaa actacggcga tgccagaatt tacccggccg acactgtcca cgtgccagac
    61441 taagaaaaag tgacaggctg ctgagagatt cagatggcgt aaaggtccgt tcagttagct
    61501 gcgacatatt catgaaatca atggttatac atgacgtcga tttcaccatt gcgtatctta
    61561 accaaacatc aatagtgtga ttactaacgt aaattttagg gttttgttga tatttcgttg
    61621 aagttaatga cccggattgg catatggagt attcagaata tttatgaaaa agcggaaaac
    61681 cgtgaagaag cgttacgtta ttgcgctggt gatagtcatc gccggactga ttacgttatg
    61741 gagaattctt aacgcacccg tgccgactta tcagacactg attgtgcgcc ccggtgattt
    61801 acagcaaagc gtgctggcga ccggaaagct ggacgcgctg cgtaaggttg acgtgggcgc
    61861 gcaggtcagc ggtcagttga aaactctgtc ggtggcgatt ggcgataaag taaaaaaaga
    61921 ccagctttta ggggttattg atcctgaaca ggctgaaaac cagattaagg aggtcgaagc
    61981 aacgctgatg gagctacgtg cgcagcggca gcaggcggaa gcggagctga aactggcgcg
    62041 ggtgacgtat tcccgtcagc aacgtctggc acaaacgcag gcggtttcac agcaggatct
    62101 cgacaccgcc gcgacggaga tggctgtgaa acaggcgcaa attggcacca ttgacgcgca
    62161 aatcaagcgc aatcaggcct ctctcgatac ggctaaaacc aatctcgatt acactcgcat
    62221 cgttgccccg atggccgggg aagtcacgca aatcaccact ctgcaaggcc agacggtgat
    62281 tgccgcacaa caagcaccga acattctgac gctggcagat atgagcacca tgctggtaaa
    62341 agcgcaggtt tctgaagcgg atgtaatcca cctgaagccg gggcaaaaag cctggtttac
    62401 ggtacttggc gatccactga cgcgctacga ggggcaaatc aaggatgtac taccgacgcc
    62461 ggaaaaggtt aacgacgcta ttttctatta cgcccgtttt gaagtcccca accccaatgg
    62521 tttgctgcgg ctggatatga ctgcgcaagt gcatattcag ctcaccgatg tgaaaaatgt
    62581 gctgacgatc cctctgtcgg cgttaggcga tccggttggc gataatcgtt ataaagtcaa
    62641 attgttgcgt aatggtgaaa cacgcgagcg tgaagtgacg attggcgcac gtaacgatac
    62701 cgatgttgag attgtcaaag ggcttgaagc gggcgatgaa gtggtgattg gtgaggccaa
    62761 accaggagct gcacaatgac gcctttgctc gaattaaagg atattcgtcg cagctatcct
    62821 gccggtgatg agcaggttga ggtgctgaag ggcatcaccc tcgatattta tgccggtgag
    62881 atggtagcga ttgttggcgc ttcaggttcc ggtaaatcga ccctgatgaa tattctcggc
    62941 tgtctggata aggccaccag cggcacctat cgcgtcgccg gtcaggatgt tgccacactg
    63001 gacgccgatg cgctggcgca actgcgccgc gagcatttcg gctttatttt ccagcgttac
    63061 catttacttt cgcatttaac cgccgagcag aacgttgaag tacccgccgt ctatgctggt
    63121 cttgagcgga aacagcgact gcttcgtgcc caggagttgc tgcaacggct ggggctggaa
    63181 gaccgtacag agtattatcc ggcacagctt tcgggtggtc agcaacagcg cgtcagcatc
    63241 gcgcgggcat tgatgaacgg tggtcaggta attcttgccg atgaaccaac cggcgcactg
    63301 gacagccatt ctggcgaaga ggtgatggcg atcctgcatc agctgcgcga tcgtgggcat
    63361 acggtgatta tcgtcaccca cgatccgcag gtcgctgctc aggccgagcg ggtgatcgaa
    63421 attcgcgacg gcgaaattgt gcgcaatcct cccgccattg aaaaagtgaa tgttgctggc
    63481 gggacggagc ctgttgtcaa cacggtgtct ggctggcggc agtttgtcag cggttttaac
    63541 gaggcgctga cgatggcatg gcgggcgctg gcagcgaata aaatgcgtac tttactgacc
    63601 atgctgggga ttattatcgg tattgcgtcg gtggtttcca ttgtcgtggt gggtgacgcc
    63661 gccaaacaaa tggtgctggc ggatattcgt tctattggta cgaatactat tgatgtctat
    63721 cccgggaaag attttggcga tgacgatccg caatatcagc aggcgctgaa gtacgacgac
    63781 ttaatcgcca tccaaaaaca accgtgggtc gcctcagcca cacctgccgt ctcgcaaaac
    63841 ctgcgcctgc gttataacaa tgttgatgtt gctgccagtg ccaatggcgt gagcggcgat
    63901 tattttaatg tctatggcat gaccttcagt gaaggaaaca cctttaatca ggagcagctg
    63961 aacggtcgtg cgcaggtcgt ggttctcgac agtaatactc gccgccagct tttcccccat
    64021 aaagcagatg tggttggcga ggtgattctg gtcggcaata tgcccgccag agtcattggt
    64081 gtggcggaag aaaaacagtc gatgtttggt agcagtaaag tgctgcgtgt ctggctacct
    64141 tacagcacga tgtccgggcg agttatgggc cagtcgtggc tgaactccat tactgtcagg
    64201 gtaaaagaag gatttgacag cgccgaggcg gaacagcaac tcacgcgttt actttcactg
    64261 cgccacggaa agaaggattt ctttacctgg aacatggacg gcgtcttgaa aactgttgaa
    64321 aagaccacac gtactttaca actgtttctg acgctggtgg cggtgatttc gctggtggtg
    64381 ggcggtattg gtgtaatgaa tattatgctg gtgtcagtga ccgagcggac gcgggaaatt
    64441 ggcattcgca tggctgtagg tgcgcgagca agcgatgttt tgcaacagtt cctgatcgaa
    64501 gccgtactgg tttgcctggt cggtggcgcg ttgggaataa cactgtcact gttaattgct
    64561 ttcaccttgc agcttttctt acccggctgg gagattggtt tttcaccgtt ggcactgctg
    64621 ctggcgtttc tctgctcgac ggtcaccggg attttatttg gatggttacc cgcacgaaat
    64681 gcggcacgac tggatccagt agatgctctg gcacgagagt aatttttgag ataaaaatgc
    64741 cagccgatcg ggctggcatt ttgcctttag gatgtacaca atgagacaga agagctatgc
    64801 gactgccgct tctacttcga cgggcacaat aacactggcg tgattgcctt ttggcccctg
    64861 gtggacatca aactgaacgg attgtccagc ttttagcgtt ctgtaaccat ccatctgaat
    64921 ggtggaataa tgagcgaaaa tatcttcgcc gccgccttca gggcagatga aaccaaaccc
    64981 tttggcattg ttgaaccact taacagtacc cttttccatg cttcgacatc cttcgcaaat
    65041 cttatacaag taagatggaa taaaccgggg tcagagaggg ggctgttcaa aacctcgcca
    65101 actctagaaa tacaatttag agaattaggg cgagccgtca agcgtttgac aggggccagg
    65161 gggcaggtat gaatcaaaaa tttgaagcag ttaacgctat tgacaggaat gtgacagatg
    65221 tcgctgatgc caacgataga tgatagttat ctatcatgtg gagtagattg gtcaggcaaa
    65281 taagctcttg tcagcggcag ggcgttctgc cgataaccgt aaccgaagat gataactgac
    65341 aatgggtaaa acgaacgact ggctggactt tgatcaactg gcggaagaaa aagttcgcga
    65401 cgcgctaaaa ccgccatcta tgtataaagt gatattagtc aatgatgatt acactccgat
    65461 ggagtttgtt attgacgtgt tacaaaaatt cttttcttat gatgtagaac gtgcaacgca
    65521 attgatgctc gctgttcact accaggggaa ggccatttgc ggagtcttta ccgccgaggt
    65581 tgcagaaacc aaagtggcga tggtgaacaa gtacgcgagg gagaatgagc atccattgct
    65641 gtgtacgcta gaaaaagcct gaatgcaggc ataaaaattg ggggaggtgc ctatgctcaa
    65701 tcaagaactg gaactcagtt taaatatggc tttcgccaga gcgcgcgagc accgtcatga
    65761 gtttatgacc gtcgagcact tgttactggc gctgctcagt aacccatctg cccgggaggc
    65821 gctggaagcg tgttctgtgg atttggttgc gctccgtcag gaactggaag cctttattga
    65881 acaaaccaca cccgttctgc ctgccagtga agaggagcgc gacacacagc cgacgctgag
    65941 ttttcagcgt gtactgcaac gtgcggtctt ccatgtccaa tcctccggtc gcaatgaggt
    66001 aaccggtgca aacgttctgg tcgctatctt tagcgaacag gagtcgcagg cggcatatct
    66061 gttgcgtaaa catgaagtca gccgtctcga tgtggtgaac tttatctctc atggcacgcg
    66121 taaagacgag ccgacacagt cttctgatcc tggcagccag ccaaacagcg aagaacaagc
    66181 tggtggggag gaacgtatgg agaatttcac gacgaacctg aatcagcttg cgcgcgtggg
    66241 cggaatcgac ccactgattg gtcgtgagaa ggagctggag cgtgctattc aggttctctg
    66301 ccgtcgccgt aaaaacaacc cgctgctggt gggggaatct ggtgtcggta aaaccgcgat
    66361 tgcggaaggt cttgcctggc gaattgttca gggcgatgtg ccggaagtga tggctgactg
    66421 tacgatttac tctctcgata tcggttctct gttagcgggc actaaatatc gcggcgactt
    66481 tgaaaaacgt tttaaagcgt tgctcaagca gctggagcag gacactaaca gcatcctgtt
    66541 tattgatgag atccacacca ttatcggtgc gggggcagcg tctggtggcc aggtcgatgc
    66601 ggctaacctg atcaaaccgt tgctctccag cggtaaaatt cgcgtaattg gttcgacaac
    66661 ctatcaggag ttcagcaaca ttttcgagaa agaccgtgct ctggcgcgtc gcttccagaa
    66721 aattgatatt actgaaccgt cgatcgaaga aactgttcaa atcatcaatg gcctgaaacc
    66781 gaagtatgaa gcgcaccacg acgtgcgtta taccgcaaaa gcggtgcgtg cagcggtaga
    66841 gctggcggtg aaatacatta acgatcgtca tctgccggat aaagccattg acgttatcga
    66901 cgaagcgggc gctcgcgcac gcctgatgcc ggtaagcaaa cgcaagaaaa ccgttaatgt
    66961 ggcggatatt gagtccgtgg tggcccgtat tgcgcgcatt ccagagaaga gtgtttctca
    67021 gagtgaccgc gataccctga aaaacctcgg cgatcgcctg aaaatgctgg tcttcggtca
    67081 ggataaagcc attgaggcgc tgactgaagc cattaagatg gcgcgtgcag gtttaggtca
    67141 cgaacataaa ccggttggtt cgttcctgtt tgccggccct accggggtcg ggaaaacaga
    67201 ggtgacggta cagctttcga aagcgttggg cattgagctg ctgcgctttg atatgtccga
    67261 gtatatggaa cgccataccg tcagccgtct gattggtgcg cctccgggat acgttggttt
    67321 tgatcaggga ggtttgctga ctgatgcggt catcaagcat ccacatgcgg tgctgttgct
    67381 ggacgaaatc gagaaagcgc atccggacgt gttcaatatt ctgttgcagg tgatggacaa
    67441 cggtacgctg accgataaca acggacgcaa agcggacttc cgtaacgtgg tgctggtgat
    67501 gaccaccaac gccggggtac gtgaaactga gcgtaaatcc attggtctta tccaccagga
    67561 taacagcacc gatgcgatgg aggagatcaa gaagatcttt acaccggaat tccgtaaccg
    67621 tctcgacaac attatctggt ttgatcatct gtcaaccgac gtgatccatc aggtggtgga
    67681 taaattcatc gtcgagttgc aggttcagct ggatcagaaa ggtgtttctc tggaagtgag
    67741 ccaggaagcg cgtaactggc tggccgagaa aggttacgac cgggcaatgg gcgcacgtcc
    67801 gatggcgcgt gtcatccagg acaacctgaa aaaaccgctc gccaacgaac tgctgtttgg
    67861 ttcgctggtg gacggcggtc aggtcaccgt cgcgctggat aaagagaaaa atgagctgac
    67921 ttacggattc cagagtgcac aaaagcacaa ggcggaagca gcgcattaat ctgattgtta
    67981 ggtaggttgg tcaagtccgt aatctcgaaa gaggttacgg actttttgtt tatggggtgg
    68041 aggaggttca gacccttttt ttaatgatga tggtaagttg ttgataatta gtgctgcggg
    68101 aaggtaagga taaaaaaggg tgctgcagga gaatgggatg gttttgcttt attaacaacg
    68161 ggctaaacgt gtagtatttg agttcactgc cgtacaggca gcttagaaat cgacggggtg
    68221 cggtaaaacc tttgcgaacg cgttcactgc cgtacagaca gataaaatgc gaaaaaaaaa
    68281 gttcgcactt tcgtacgagc tcttctttaa atatggcggt gaggggggga ttcgaacccc
    68341 cgatacgttg ccgtatacac actttccagg cgtgctcctt cagccactcg gacacctcac
    68401 caaattgttt tgtcgcctga cctcatgggt ggcaacgggg cgctactata gggagttgga
    68461 gtaaaacggt caagaagaat tttaatgata attattgttt gctcatactg taaacaagtt
    68521 gtgcagtata tctacatcga gacaagttac ggacttatac ttccaaagta cttcatacat
    68581 atcacaaaat aaaaaggccg gttaaaccga ccttttactc gttctttctc ttcgcccatc
    68641 aggcggtaaa acaatcagcg actacggaag acaatgcggc ctttgctcag gtcgtacggg
    68701 gtcagttcaa cagtcacttt gtcgcccgtc aggatgcgga tgtagttttt gcgcatttta
    68761 ccggagatgt gtgcagtaac cacgtgaccg ttttctaact ctacgcggaa catggtatta
    68821 ggcaacgttt caagaacggt accttgcatt tcaatattgt cttctttggc catctaatcc
    68881 tctggggtat cactaccgta atttgaaccg gcaagataat gccgaagttc tgtaaataag
    68941 taaagatttg cgcgctaaat cgcaacaaac aggttcggca cattactccg aaaacacacg
    69001 gctaagccgc accaaaagcg caacgtataa gggagcggtg agataaacga tgggcgttac
    69061 ctgacgcgaa aaattcctta tcggcagcgg ggtaatgagc gtaaccaact ctgcgaccgc
    69121 aattataaca ctctggggag aaatgtgccg aaaacattca ttcttgtggt gaaaacaagc
    69181 atcgtggtac ccagaaatta ttcggcaatc gtccgaggcg catttgattg agataattaa
    69241 ggtaatcccg gcggggaatt tcgcaggcac caagcgatgc tgtgtgatcg ttaaggacct
    69301 ggcagtcgat aagcttaccg ccatgaccga taaattcctc acagaatacc agaagcgccg
    69361 ttttagacgc attttccatc cggctgaaca tggactcgcc acaaaatagc gttccctggg
    69421 ccacgccgta cataccgccg acaagctcat cttcacgcca gacttcaatg gagtgggcat
    69481 ggccgagttc gtgaaggcga tggtaggctt cgaccacgcc acgcgtgatc caggttcctt
    69541 cttcgcgatc gctggcacag ccttcaatga cctgaccaaa agcgtaattc atcgtgacac
    69601 gatagggcga gcgtttatga aatcgcttca tactacggct gatatgcagt gattctggcc
    69661 atagcaccgc gcggggatcg ggcgaccacc agaggatggg gtcgcctgga gaaaaccacg
    69721 gaaaaatacc acgctggtaa gccattaaca ggcgcgcagg gctaagatcg cccccaagtg
    69781 ccagcaggcc gttaggctca cgtaatgcgc cttccgggga agggaaggct attgaatggc
    69841 gagaaagctg aaccaggcgc atgaccgcaa aactccacgc aagtcggatc gttcaataat
    69901 agcttacaaa ccctgcttga actggtaata acgcccctgt ctggcaagca gctctgcgtg
    69961 agtaccttgc tcaataattt gcccgttgtc catcactatt atttgttgga aacgagagag
    70021 tccgcgaagt cgatgggtga ccattaacac cgttttctca cgcatcattt ctgcaagcaa
    70081 ttcaaggatc tggctttcgg ttgtggcatc taagccttcg gtaggttcat ccagcaacac
    70141 cagtggcgca tcatgtaaca gcgcacgggc gatagccaga cggcgcagtt caccaccgga
    70201 gagctggcgt ccgccttcac ctaaccaact gttgagacct gcatcctcga gcagcttctc
    70261 caggccaacg cgacgcaagc tctccgccag agcctcatca ctactgccag gcgaggcgag
    70321 taacagatta tcacgcagcg tggcgctaaa cagatgcact cgctgaggaa caacgctgat
    70381 ggtctgtcgt agagccgctt cattcaggct ggctatgggg ctatcgttaa gcaaaatctc
    70441 gccctgttgc gggtcccaag cgcgggtcag cagttgtaac agtgttgatt tgccgcatcc
    70501 ggttcgcccg agaatcgcaa tatgttcccc ggcgtttacc tgaagagaaa tccctttaag
    70561 tgcctgttgg gattgctccg gataagtgaa ctgaacatcc cgtaatgtca gcgaaacgcg
    70621 atcggcaaca cgagtttggg tatcagggaa ggtgacttcc ggtttttgat ccgttaaatc
    70681 agtgatccga acggcagagg caatgacttg ccccagatgc tgaaatgcac ccgttactgg
    70741 tgccagtgct tcaaacgcgg ctaacgcgca gaagacaaac agggcaatta acgcgccggg
    70801 ttgagcattg ccgccaacgc cgccagacgc catccacagc atcaggatca ccgctaacgc
    70861 gccaatgagt agcattatcg cttgcgacaa tgcggtcagt tcagattgac ggcgttgcgc
    70921 ttccagccat tgaatttctg tattctctag ttgcgtgcga taacgatcgc tggcaccaaa
    70981 aatggtcagc tcagcttgcc cttgcagcca ggccgtcagt tgttggcgat actgtccgcg
    71041 aagatgagtc agattttgcc cggtgctttt tcccgcacga taaaacagcg gtggcatcag
    71101 gaaaagcgtc agtaacataa tgccgcccag cgtaaaggcg agggtgaaat caaggaaact
    71161 taacccgatt gtcaccacca taatcaccac aaaagcgccc accagcggcg agataacgcg
    71221 cagataaaga tgatcgagcg tatcaacatc cgccaccacg cgattgagca attcgccctg
    71281 acgatagcgc gccagtccgg caggggagag gggcagcaat ttgctgaagg tgtaaatgcg
    71341 cagatgctgc aacacgcgga aagtcgcgtc gtgacttacc agacgttcaa aataacgccc
    71401 ggcagtacgg gtgattgctg cgccacgcac gcccgcagcg ggtagcatat agttgaagct
    71461 gtacagtccg gcaacccccg caaccgctga ggccgagagg aaccagccgg aaagtgtcaa
    71521 cagaccgata ctggcgagca gcgtgacaat tgccagcacg ataccaagac ttaacatcca
    71581 tttatgacgt ttatacagtg ccagataggg tagcaaagcg cgcatttaaa tctcctcctg
    71641 acgatgggcc agtaatgtgg cgaatgggcc accagccaca cttaattccg cgtaacgtcc
    71701 ttgctcaata atccggccat cctgcataac ccaaatgaca tcccagtcag caagatcttc
    71761 taactggtgg gtgaccatta acgttgtctg gcgcagagag gcggcattca gcgcctccat
    71821 tacgcgctgt tcactgtgag catcaaggct ggcagcgggt tcatccaaca gtaatagcga
    71881 acagggattt agtaacgcac gggccaccgc cacgcgctgc gcctgcccca cggaaaggcg
    71941 ggcagcctgg tcgccaacag gcgtatcaac gccttgtggc aggagcggta gaaactcgct
    72001 gacccaggcg ttatccagcg ctgcttgtaa ttcttgttcg ctggcatcag gtcgcgccag
    72061 tagtacgtta tcccgcaatg ttgctgccgg taattgtggg ttttgcccaa cccaggagag
    72121 atgtttacgc catgattctg gtgataaatc gcgtaattct atcccgttga ttcgtaatga
    72181 tccctgatat gaaagaaaac cagaaagcgc gttcagcagt gagcttttac ctgaaccgct
    72241 gcgaccaacc aacactgcac gttggcctgc tggcaaagta aagttcagcg gtccggccag
    72301 cgttttacct tccggcgacg tgataaacag atcctcggcc tcaatggtca ccggatcggt
    72361 cgatgctaat tccgcctcac cgcgctgcgg atgggcgagc ggggtttcca taaacgtttt
    72421 cagactgtca gctgcaccaa cagcctgggc tttagcatga taaaacgtac cgagatcgcg
    72481 caatggctgg aaaaactctg gcgcaaggat cagggccaga aaacccgcag ccagcgtcac
    72541 accggtatcg tagtgaccaa aatccagctc gccgagatag gaaaaaccaa agtagaccgc
    72601 caccagagca attgacagcg aggtaaaaaa ttcgagaatg ccggaggata aaaacgccag
    72661 ccgtagcact tccattgtcc gttggcggaa atcttccgaa gcagaacgaa tactttcaat
    72721 ttcagcttca ccacgaccaa aaatacgcaa tgtttccatg ccgcgcaggc gatcgaggaa
    72781 atgcccactt aagcgagcaa gagcgagaaa gttacgccgg ttagcatcgg cagcccccat
    72841 cccaaccagc gccataaaca acggaattaa cggtgctgtg cccagcagaa tgagcgccgc
    72901 agcccagtta gaggggaaga tcgccaccac aatcagcaac ggcaccgaca ctgccagcgc
    72961 catttgcggc aggtagcgtg catagtaatc atgcatatcg tcaatttgct cgagtaccaa
    73021 cgtcgcccag ctccccgcag gtttaccctg aatccacgct ggccctgctt gttgcagacg
    73081 gtcgagaacc tgacggcgga tggcaaagcg gatatgctgc ccggcgtgat aacccacccg
    73141 ttcgcgtaac cagaccaccc atgcgcgcag tacaaaggtc agaaccagta acgtaaaggg
    73201 aagcagcagg gcttcacggg gaatattctc cataatcata tgttgcagaa ttcgcgccat
    73261 gaaccaggcc tgggcaatga tcaatatgcc gcttacaaag cccagcagac gagaaatatt
    73321 cagccaacgt tgggagatga cgctttgctg ttttaaccag cgggttaact ctttttgacg
    73381 ggatttattc attgcacgct tagcaggtga gttatcagaa ttatttgcag agcaatgtta
    73441 caacggggaa aaaataaagg cgacccatag tcgcatggtg tcaccttctt tacttttgtt
    73501 actgatttgt aaaattattt tgcgtcagct aaaccatcga ggtagcgttc cgcatcaagt
    73561 gctgccatgc agcctgtacc ggccgaagta atggcctgac gataaatatg atccatcacg
    73621 tcacccgcgg caaagacgcc agggatgctg gtctgggtgg cattaccatg aatacccgac
    73681 tgcactttga tgtagccgtt ttccagttcc agctgccctt cgaaaatggc agtattcggg
    73741 ctgtgaccga tagcaacaaa cagaccagca acgtcgagtg actcgatgtt atcgctgttt
    73801 tgcgtatcgc gcagacgaac gccagtgaca cccatttgat cgccggtcac ttcttccagc
    73861 gtacggttgg tgtgcagaat gatgttgccg ttctccactt tatccatcag acgcttaata
    73921 aggatttttt ccgcgcggaa accgtcacgg cggtgaatca gatgcacttc cgaagcgatg
    73981 ttagacagat acagcgcctc ttcaaccgcg gtattgccgc cgccgatgac cgcaactttc
    74041 tggttgcgat agaagaaacc gtcgcaggtt gcacaagcag aaaccccacg gcctttaaag
    74101 gcttcttcag agggcaggcc gagatagcgt gcagaagctc cggtggcaat aatcagcgcg
    74161 tcgcaagtgt attcgccgtt atcgccattc agacggaacg gacggttttg cagatccacc
    74221 ttgttgatat gatcaaaaat gatctcagtt tcaaacttgg tggcatgttc gtgcatgcgc
    74281 tccattaata acggaccggt cagatcgttt ggatcgccag gccagttttc cacttccgtg
    74341 gtggtggtca gttggccgcc tttttccatg ccggtaatca gcacaggttg caggttggcg
    74401 cgcgccgcgt agacagcagc ggtgtatccc gccgggcctg aacccaggat aagcagttta
    74461 ctgtgtttgg tcgtgcccat gagatcccca tagttgttgg cagacaatgg gcaggattgt
    74521 agggaattta cagacgtaaa aaaagagtat gacgattttg ttaacaattt gtgcaatcgg
    74581 cagcatcgat aagcaggtca aattctcccg tcattatcac ctctgctact taaatttccc
    74641 gctttataag ccgattaaat gatgaataaa cgcccctgtt aatgaatatc tggcatgttg
    74701 tactaaaaat cgatgttttg ctttgacaat cccctggtgt tttgcgaaaa cattcgagga
    74761 agaaaaaaaa cagtattctt atatgcgcat aaccatgcat gtaaatacca tgtttaccgt
    74821 gctagtgaaa tctacgtatg gcgtggacag acgccattcg tgatgtcgat agctgccaca
    74881 aggcaacggt cttctcaccg tagacccagg cattgcgcgc cgtgaatctt catgatttcg
    74941 gtctatcgtg acgggtagcg actctgaaca gtgatgtttc agggtcagac aggagtaggg
    75001 aaggaataca gagagacaat aataatggta gatagcaaga agcgccctgg caaagatctc
    75061 gaccgtatcg atcgtaacat tcttaatgag ttgcaaaagg atgggcgtat ttctaacgtc
    75121 gagctttcta aacgtgtggg actttcccca acgccgtgcc ttgagcgtgt gcgtcggctg
    75181 gaaagacaag ggtttattca gggctatacg gcgctgctta acccccatta tctggatgca
    75241 tcacttctgg tattcgttga gattactctg aatcgtggcg caccggatgt gtttgaacaa
    75301 ttcaataccg ctgtacaaaa acttgaagaa attcaggagt gtcatttagt atctggtgat
    75361 ttcgactacc tgttgaaaac acgcgtgccg gatatgtcag cttaccgtaa gttgctgggg
    75421 gaaaccctgc tgcgtctgcc tggcgtcaat gacacacgga catacgttgt tatggaagaa
    75481 gtcaagcaga gtaatcgtct ggttattaag acgcgctaac acggaacagg tgcaaaatcg
    75541 gcgtattttg attacactcc tgttaatcca tacagcaaca gtactggggt aacctggtac
    75601 tgttgtccgt tttagcatcg ggcaggaaaa gcctgtaacc tggagagcct ttcttgagcc
    75661 aggaatacac tgaagacaaa gaagtcacat tgacaaagtt aagtagcggc cgccgccttc
    75721 tggaggcgtt gctgatcctt attgtcctgt ttgccgtctg gttgatggct gccttactaa
    75781 gctttaaccc ttcggacccc agctggtcgc aaacggcctg gcatgaacct atccataatt
    75841 taggtgggat gcccggtgcg tggttggcag atacgctgtt ctttattttt ggcgtgatgg
    75901 cttacaccat tcccgtcatt attgtcggcg gttgttggtt tgcctggcgt catcagtcca
    75961 gcgacgaata cattgattat tttgccgttt cgctacgcat cattggcgtt ttggcgctca
    76021 tccttacctc ctgtggtctg gcggcaatca acgctgacga tatctggtat tttgcctccg
    76081 gtggcgtcat tggcagctta ctaagtacta cgctacaacc actgctacac agtagcgggg
    76141 gaactattgc gctgctctgc gtttgggctg cgggcctgac gctgttcacc ggttggtcat
    76201 gggtgaccat tgctgaaaaa ctcggcggct ggattttaaa cattctcacc ttcgccagta
    76261 atcgtacccg tcgcgatgat acctgggtcg atgaagatga atatgaagat gacgaagagt
    76321 atgaagatga aaaccacggc aaacagcatg aatcacgccg tgcccgtatt cttcgcggcg
    76381 cgctagcgcg tcgtaaacgg ttggcggaaa aattcattaa tccgatgggg cggcaaacag
    76441 acgctgcgtt gttctccggt aagcggatgg atgatgacga agagattacc tacactgcac
    76501 gcggtgtggc tgccgacccg gacgacgtcc tattttcggg caatcgtgca acgcagccag
    76561 aatatgacga atacgatcca ttattaaacg gtgcgccaat taccgaacct gtcgctgtag
    76621 cagctgctgc taccacggcg acacaaagct gggctgcgcc ggttgaacct gtgactcaga
    76681 cgccgcctgt tgcctctgtt gatgttccac cctcgcaacc tacagtagcc tggcagcctg
    76741 taccgggtcc acaaacggga gagccggtta ttgctcctgc accggaaggt tacccacagc
    76801 agtcacaata tgcgcagcct gcagtgcaat ataatgagcc gctgcaacaa ccagtacagc
    76861 cgcagcagcc gtattatgca cctgcagctg aacaacctgc gcaacaacct tactacgctc
    76921 ctgcggcgga acaacctgtt cagcaaccgt attacgcaac tgcgccggaa cagcctgcac
    76981 aacagccgta ttacgcccct gcgccagaac aaccggtggc aggtaacgcc tggcaagccg
    77041 aagagcagca atccactttt gctccacagt ctacatacca gactgagcaa acttatcagc
    77101 aaccagccgc tcaggagccg ttgtaccaac agccgcaatc cgttgaacag cagcctgttg
    77161 tggagcctga acccgttgta gaagagacaa aacccgcgcg tccgccgctt tactattttg
    77221 aagaagtgga agagaagcga gcccgtgaac gtgaacaact tgcggcctgg tatcaaccga
    77281 ttccagaacc ggttaaagaa ccagaaccga tcaaatcttc gttgaaagcg ccttctgttg
    77341 cagcagtacc tccagtagaa gccgctgccg ctgtttctcc gctggcatct ggcgtgaaaa
    77401 aagcgacact ggcgacgggg gctgccgcaa ccgttgccgc gccagtcttc agtctggcaa
    77461 atagcggtgg accgcgtccg caagtcaaag aggggattgg cccgcagttg ccacgaccga
    77521 aacgtatccg cgtgccaact cgtcgtgaac tggcgtctta cggtattaag ctgccctcac
    77581 agcgtgcggc ggaagagaaa gcccgtgaag cccagcgcaa tcagtatgat tctggcgatc
    77641 agtataacga tgatgaaatc gatgcgatgc agcaggatga actggcacgt cagttcgccc
    77701 agacacagca gcaacgctat ggcgaacagt atcaacatga tgtgcccgta aacgcagaag
    77761 atgcagatgc tgcggcagag gctgaactgg ctcgtcagtt tgcgcaaact caacaacaac
    77821 gttattccgg cgaacaaccg gctggggcga atccgttctc gctggatgat tttgaatttt
    77881 cgccaatgaa agcgttgctg gatgatggtc cacacgaacc gttgtttacg ccaattgttg
    77941 aacctgtaca gcagccgcaa caaccggttg caccgcagca gcagtatcag cagccgcaac
    78001 aaccagttcc gccacagcag caatatcagc agccgcaaca gccggttgcg ccgcagccgc
    78061 agtatcagca gccacaacag caggttgcgc cgcagccaca atatcagcag ccgcaacaac
    78121 cggttgcgcc acagccgcaa tatcagcagc cgcaacaacc agttgcgccg cagccgcagt
    78181 atcaacagcc gcaacaaccg gttgcaccgc agcagcagga taccctgctt catccgctgt
    78241 tgatgcgtaa tggcgacagc cgtccgttgc ataaaccgac gacgccgctg ccttctctgg
    78301 atttgctgac accgccgccg agcgaagtgg agccggtaga tacctttgcg cttgaacaaa
    78361 tggctcgcct ggtggaagcg cgtctggctg atttccgtat taaagccgat gtcgtcaatt
    78421 actctccggg gccggttatc actcgctttg aacttaacct ggctcctggc gtaaaagcgg
    78481 cgcgcatttc taacttgtca cgggaccttg cccgttcact ttcgacggtg gcggtgcgtg
    78541 tcgttgaagt tattcctggc aaaccctatg taggtctgga gttaccaaat aaaaaacgac
    78601 aaaccgttta tctgcgcgaa gttttggata acgccaaatt ccgcgataat ccgtcgccat
    78661 taacagtggt gctgggtaaa gatatcgccg gtgagccggt ggttgccgat ctggcgaaaa
    78721 tgccgcactt gttggttgcg gggactaccg gttccggtaa atctgtcggt gtgaacgcga
    78781 tgatcctgag catgctttat aaagcacagc cagaagatgt gcgtttcatc atgatcgacc
    78841 cgaaaatgct ggagctttcg gtttatgaag gcattccgca tctgttaacg gaagtcgtta
    78901 ctgatatgaa agatgccgcc aacgcgctgc gctggtgtgt taacgagatg gagcgtcgtt
    78961 ataaactgat gtctgcgctg ggtgtgcgta atctggcggg ttataacgaa aaaattgctg
    79021 aagccgatcg catgatgcgt ccgattccag acccgtactg gaagccgggt gacagtatgg
    79081 atgcccagca tccggtgctg aaaaaagaac catacattgt ggtgttggtt gacgaatttg
    79141 ccgacctgat gatgacggta ggtaaaaaag tggaagagct gatagcacgt ctggcgcaaa
    79201 aagcccgtgc cgcgggtatc cacctcgtac tggcaactca gcgtccatcg gttgatgtta
    79261 ttactggtct gattaaagcg aatattccga cccgtatcgc ctttaccgta tccagtaaga
    79321 ttgactcacg taccattctt gatcaggctg gcgcggaatc actgctgggg atgggggata
    79381 tgctctactc tgggccgaac tccacgttgc cggtacgtgt ccatggtgct tttgttcgcg
    79441 atcaggaagt tcatgccgtg gtgcaggact ggaaagcgcg tggtcgccca cagtatgttg
    79501 atggcatcac ttccgacagt gaaagcgaag gtggcgcggg cggtttcgat ggcgctgaag
    79561 aactggatcc gttgttcgat caggcggtgc agtttgtcac tgaaaaacgc aaagcgtcaa
    79621 tttctggcgt acagcgtcag ttccgcattg gttataaccg tgcagcgcgt attatcgaac
    79681 agatggaagc gcaggggatt gtcagcgaac aggggcacaa cggtaatcgt gaagtgctgg
    79741 ccccaccgcc gtttgactaa ttaatgcatt gccggataag gcgcggtagc gtcgcatccg
    79801 gcactctatc aactgaaaat tcagtatttt cttctttcct caagctgatt attagcctgg
    79861 aatagagagt agagggaact cccgatcggg agtgacgtaa tttgaggaat aatgatgaaa
    79921 aaaattgcca tcacctgtgc attactctca agcttagtag caagcagcgt ttgggctgat
    79981 gccgcaagcg atctgaaaag ccgcctggat aaagtcagca gcttccacgc cagcttcaca
    80041 caaaaagtga ctgacggtag cggcgcggcg gtgcaggaag gtcagggcga tctgtgggtg
    80101 aaacgtccaa acttattcaa ctggcatatg acacaacctg atgaaagcat tctggtttct
    80161 gacggtaaaa cactgtggtt ctataacccg ttcgttgagc aagctacggc aacctggctg
    80221 aaagatgcca ccggtaatac gccgtttatg ctgattgccc gcaaccagtc cagcgactgg
    80281 cagcagtaca atatcaaaca gaatggcgat gactttgtcc tgacgccgaa agccagcaat
    80341 ggcaatctga agcagttcac cattaacgtg ggacgtgatg gcacaatcca tcagtttagc
    80401 gcggtggagc aggacgatca gcgcagcagt tatcaactga aatcccagca aaatggggct
    80461 gtggatgcag cgaaatttac cttcaccccg ccgcaaggcg tcacggtaga tgatcaacgt
    80521 aagtagaggc acctgagtga gcaatctgtc gctcgatttt tcggataata cttttcaacc
    80581 tctggccgcg cgtatgcggc cagaaaattt agcacagtat atcggccagc aacatttgct
    80641 ggctgcgggg aagccgttgc cgcgcgctat cgaagccggg catttacatt ctatgatcct
    80701 ctgggggcca ccgggtaccg gcaaaacaac cctcgctgaa gtgattgccc gctatgcgaa
    80761 cgctgatgtg gaacgtattt ctgccgtcac ctctggcgtg aaagaaattc gcgaggcgat
    80821 cgagcgcgcc cggcaaaatc gcaatgcagg tcgccgcact attctttttg ttgatgaagt
    80881 tcaccgtttc aacaaaagcc agcaggatgc atttctgcca catattgaag acggcaccat
    80941 cacttttatt ggcgcaacca ctgaaaaccc gtcgtttgag cttaattcgg cactgctttc
    81001 ccgtgcccgt gtctatctat tgaaatccct gagtacagag gatattgagc aagtactaac
    81061 tcaggcgatg gaagacaaaa cccgtggcta tggtggtcag gatattgttc tgccagatga
    81121 aacacgacgc gccattgctg aactggtgaa tggcgacgcg cgccgggcgt taaatacgct
    81181 ggaaatgatg gcggatatgg ccgaagtcga tgatagcggt aagcgggtcc tgaagcctga
    81241 attactgacc gaaatcgcag gtgaacgtag cgcccgcttt gataacaaag gcgatcgctt
    81301 ttacgatctg atttccgcac tgcataagtc ggtacgtggt agcgcacccg atgcggcgct
    81361 ctactggtat gcgcgaatta ttaccgccgg tggcgatccg ttatatgtcg cgcgtcgttg
    81421 cctggcaatt gcttccgaag atgtcggcaa tgccgaccca cgggcgatgc aggtggcaat
    81481 tgcggcctgg gattgcttta ctcgcgttgg cccggcggaa ggtgaacgcg ccattgctca
    81541 ggcgattgtt tacctagcct gcgcgccaaa aagcaacgct gtctacactg cgtttaaagc
    81601 cgcgctggcg gatgctcgcg aacgtccgga ttatgacgtg ccggttcatt tgcgtaatgc
    81661 gccgacgaaa ttaatgaagg aaatgggcta cgggcaggaa tatcgttacg ctcatgatga
    81721 agcaaacgct tatgctgccg gtgaggttta cttcccgccg gaaatagcac aaacacgcta
    81781 ttatttcccg acaaacaggg gccttgaagg caagattggc gaaaagctcg cctggctggc
    81841 tgaacaagat caaaatagcc ccataaaacg ctaccgttaa tgttatcgtt gcggtaatgt
    81901 tgttactgta tccctgtggt cgcaggctgt ggccacatct cccatttaat tcgataagca
    81961 caggataagc atgctcgatc ccaatctgct gcgtaatgag ccagacgcag tcgctgaaaa
    82021 actggcacgc cggggcttta agctggatgt agataagctg ggcgctcttg aagagcgtcg
    82081 taaagtattg caggtcaaaa cggaaaacct gcaagcggag cgtaactccc gatcgaaatc
    82141 cattggccag gcgaaagcgc gcggggaaga tatcgagcct ttacgtctgg aagtgaacaa
    82201 actgggcgaa gagctggatg cagcaaaagc cgagctggat gctttacagg ctgaaattcg
    82261 cgatatcgcg ctgaccatcc ctaacctgcc tgcagatgaa gtgccggtag gtaaagacga
    82321 aaatgacaac gtcgaagtca gccgctgggg caccccgcgt gagtttgact ttgaagttcg
    82381 tgaccatgtg acgctgggtg aaatgcactc tggcctcgac tttgcagccg cagttaagct
    82441 gaccggttcc cgctttgtgg taatgaaagg gcagattgct cgcatgcacc gcgcactgtc
    82501 gcagtttatg ctggatctgc ataccgaaca gcatggctac agtgagaact atgttccgta
    82561 cctggttaac caggacacgc tgtacggtac gggtcagctg ccgaaatttg ctggcgatct
    82621 gttccatact cgtccgctgg aagaagaagc agacaccagt aactatgcgc tgatcccaac
    82681 ggcagaagtt ccgctgacta acctggtgcg cggtgaaatc atcgatgaag atgatctgcc
    82741 aattaagatg accgcccaca ccccatgctt ccgttctgaa gccggttcat atggtcgtga
    82801 cacccgtggt ctgatccgta tgcaccagtt cgacaaagtt gaaatggtgc agatcgtgcg
    82861 cccggaagac tcaatggcgg cgctggaaga gatgactggt catgcagaaa aagtcctgca
    82921 gttgctgggc ctgccgtacc gtaaaatcat cctttgcact ggcgacatgg gctttggcgc
    82981 ttgcaaaact tacgacctgg aagtatggat cccggcacag aacacctacc gtgagatctc
    83041 ttcctgctcc aacgtttggg atttccaggc acgtcgtatg caggcacgtt gtcgcagcaa
    83101 gtcggacaag aaaacccgtc tggttcatac cctgaacggt tctggtctgg ctgttggtcg
    83161 tacgctggtt gcggttatgg aaaactatca gcaggctgat ggtcgtattg aagtaccaga
    83221 agttctgcgt ccgtatatga acggactgga atatattggc taatacccaa tttttctgaa
    83281 tctaaaaagc gcctgcgggc gctttttttg tctccctttg ataccgaaca ataattactc
    83341 ctcacttaca cgtaatacta ctttcgagtg aaaatctacc tatctctttg attttcaaat
    83401 tattcgatgt atacaagcct atatagcgaa ctgctataga aataattaca caatacggtt
    83461 tgttactgga atcaatcgtg agcaagcttg agtgagccat tatgaaaacg aaaatccctg
    83521 atgcggtatt ggctgctgag gtgagtcgcc gtggtttggt aaaaacgaca gcgatcggcg
    83581 gcctggcaat ggccagcagc gcattaacat taccttttag tcggattgcg cacgctgtcg
    83641 atagcgccat tccaacaaaa tcagacgaaa aggttatctg gagcgcctgt acagttaact
    83701 gtggtagtcg ctgcccgcta cgtatgcacg tcgtggacgg tgaaatcaaa tatgtcgaaa
    83761 cggacaatac cggcgatgac aattacgacg gcctgcacca ggttcgcgcc tgtctgcgtg
    83821 ggcgttccat gcgtcgccgt gtctacaatc cggaccgcct gaaatatccg atgaaacgag
    83881 tcggggcgcg cggtgaaggc aaattcgagc gcattagctg ggaagaagcc tacgacatca
    83941 tcgcgaccaa tatgcagcgc ctgatcaaag agtacggcaa cgagtctatc tatctgaact
    84001 atggcaccgg tacgctgggc ggcaccatga cccgctcctg gccgccggga aataccctgg
    84061 tcgcgcgcct gatgaactgc tgcggcggtt atcttaacca ttacggtgac tactcttctg
    84121 cgcaaattgc ggaaggtttg aactatacct acggcggctg ggcagatggt aacagcccgt
    84181 cggatatcga aaacagtaaa ttggtagtgc tgtttggtaa taacccaggc gaaacgcgaa
    84241 tgagtggcgg tggggtgact tactatcttg aacaggcacg ccagaaatct aatgcccgca
    84301 tgatcatcat cgatccgcgc tataccgaca ccggtgccgg gcgcgaagat gagtggatcc
    84361 ctattcgtcc aggaacagat gccgcactgg ttaacggtct ggcgtatgtc atgatcaccg
    84421 aaaacctggt ggatcaggca ttccttgata aatattgcgt tggctacgat gagaaaaccc
    84481 tgcccgctag cgcgccgaaa aatggccact ataaagctta tattctgggt gaagggccag
    84541 atggcgtggc taaaacaccg caatgggcct cacaaatcac cggtgttccg gcagacaaaa
    84601 tcatcaaact ggctcgtgaa atcggcagta ccaaaccggc gtttatcagc cagggatggg
    84661 gcccgcagcg tcacgctaac ggtgaaatcg caacccgtgc tatctcgatg ctggcgattc
    84721 tgaccggtaa cgttggtatt aacggaggca acagcggcgc gcgtgaaggt tcatacagct
    84781 taccgtttgt ccgtatgccg accttggaaa acccgatcca gaccagcatt tcgatgttta
    84841 tgtggaccga tgccattgaa cgtggcccgg aaatgacagc gctgcgtgat ggtgtacgcg
    84901 ggaaagataa gctggatgtg ccgatcaaaa tgatctggaa ctatgccggt aactgcctga
    84961 ttaaccagca ttctgaaatc aaccgtaccc atgaaatcct tcaggatgat aagaagtgcg
    85021 agctgattgt ggttatcgac tgccacatga cctcatcggc gaaatatgct gacatcctgc
    85081 tgcctgactg caccgcttcc gaacagatgg actttgcact ggatgcatcc tgcgggaata
    85141 tgtcttacgt gattttcaac gatcaggtga ttaaaccgcg ctttgaatgt aagaccatct
    85201 atgaaatgac cagcgaactg gcaaaacgtc ttggcgttga gcaacagttt actgaaggcc
    85261 gtacacagga agagtggatg cggcatctgt atgcccagtc gcgggaagcg attcctgaac
    85321 tgccaacgtt tgaagagttc cgcaagcagg ggatctttaa aaagcgcgac ccacaagggc
    85381 accacgttgc ttataaagct ttccgtgaag atcctcaggc aaatccactg accacgccat
    85441 cgggcaaaat tgagatttat tcgcaggcgc tggctgacat tgccgctacc tgggaattgc
    85501 cagaaggcga tgtaatcgat ccactgccga tctacacgcc gggctttgaa agttatcagg
    85561 atccgttgaa caaacagtat ccgctgcagc ttacgggttt ccactataaa tctcgcgttc
    85621 actcaactta cggcaacgtt gatgtgctga aagcagcttg ccgtcaggaa atgtggatca
    85681 acccgcttga tgcgcaaaaa cgcggtatca acaacggcga taaagtcagg atctttaacg
    85741 atcgtggtga ggttcatatt gaggcgaaag tgacgccacg aatgatgccg ggtgtggtcg
    85801 cactgggtga aggtgcctgg tatgacccgg atacaaaacg tgtcgataag ggcggttgta
    85861 tcaacgtact gaccactcaa cgtccgtctc ctctcgctaa ggggaatccg tcacatacaa
    85921 accttgttca ggttgaaaag gtgtaaggag taaccgatga caacccagta tggatttttt
    85981 attgattcca gccgttgcac cggttgcaaa acctgcgagc tggcctgtaa agactacaaa
    86041 gatttgacgc cagaagtcag cttccgccgc atttatgaat atgctggcgg cgactggcag
    86101 gaagataacg gtgtctggca ccagaacgtg tttgcctact atctgtcgat ttcatgtaac
    86161 cactgcgaag atccggcttg tactaaagtc tgcccgagcg gtgcgatgca taaacgtgaa
    86221 gatggttttg ttgtggtcga tgaagatgtg tgcattggct gccgctactg ccatatggct
    86281 tgcccgtatg gcgcaccgca atataacgaa acgaaaggcc atatgaccaa atgcgatggt
    86341 tgttatgacc gtgttgcgga gggtaaaaag ccgatctgtg ttgaatcttg tccgctgcgg
    86401 gcgctggatt tcggccctat cgacgagctg cgtaaaaaac atggcgatct ggcggccgtt
    86461 gcgccgttgc cgcgagctca ctttaccaaa ccgaatattg tgatcaaacc caatgccaat
    86521 agccgcccga ccggggatac cactggctat ctggcaaacc cgaaggaggt gtgagatggg
    86581 aagtggatgg catgaatggc cgctgatgat cttcacggtc ttcgggcaat gtgtagcagg
    86641 tggttttatc gttctggctt tggcgctgct caaaggcgac ctgcgagcag aagcccagca
    86701 gcgtgttatc gcctgcatgt ttggtttatg ggtgctgatg ggcattggct ttatcgcctc
    86761 tatgctccat cttggttcac caatgcgcgc ttttaactcg ctcaaccggg taggggcttc
    86821 agcactcagt aacgaaatcg ccagcggttc gatctttttt gccgtaggcg gcatcggctg
    86881 gttgctggca atgctgaaaa agctgtcacc ggcattgcgt acgctgtggc tgatagtgac
    86941 gatggttctt ggcgtcatct ttgtctggat gatggtgcgt gtgtataaca gcattgatac
    87001 cgttccgacc tggtacagca tctggacgcc gatgggcttc ttcctgacga tgtttatggg
    87061 cggcccgtta ctgggttacc tgttgttgag tctggctggc gtcgatggct gggcgatgcg
    87121 tctgctgcca gcaatttctg tactggcact ggtagtgagt ggcgtggtgt cagtgatgca
    87181 gggcgcagag ctggcgacta ttcatagttc tgtgcagcag gccgcagcgc tggtgccgga
    87241 ctatggtgcg ctgatgtcct ggcggatcgt gcttttggcc gttgccctgt gcttgtggat
    87301 tgcaccacag ctaaaaggtt atcagcctgc ggttccgcta ctatccgtct cattcattct
    87361 gcttctggca ggggaattaa tcggtcgcgg cgtattctat ggtttgcata tgaccgtggg
    87421 gatggccgtc gcaagctaat cagtaacaac cggggtttcg gccccggttc tcttttattt
    87481 ctgcttcgtt aacgtgtcat aactggtcat caaattacga taatcaggaa tgtggttaga
    87541 gaacaacgtc gccagtcctt caatatcatt acgccagtcg cgatgcagct cgcacgccac
    87601 gccgaaccat gtcatcaatt gcgcaccagc ttgcgacatg cgatcccatg ccgaatgccg
    87661 ggtaatttca ttaaaggtcc ctgacgcgtc agtcacgaca aagacgtcaa acccttcttc
    87721 aatggctgaa agcgccggga atgccacgca aacttcggtt accacaccgg caataattaa
    87781 ctgtttttta cctgtcgctt tgacagcttt tacaaaatct tcgttatccc aggcgttaat
    87841 atttcccggg cgagcaatgt aaggtgtatc ggggaattgt gctttcagtt ctggaactaa
    87901 tgggccgtta ggaccggttt caaaactggt ggtaagaata gttggtaagt tgaaatactt
    87961 agccaggtca cccagcgcca gcacgttatt tttaaactta tcaggttcga tatcccgtac
    88021 aagggaaagt aaaccagcct ggtgatcaac aagcaaaacg gcagcatcat ttttatcaag
    88081 acgaacatac ggtttggtca tcctcttctc ctttcgagag tcagtggtac gtctgaaatc
    88141 gatcagatgc gatgcattgc tctgaaagca tagacgggaa atatgagttt gctgtgacca
    88201 tgaaattttt cgactgaacg aagcgtatga aatttgtgtt agttcaataa aaacaatcag
    88261 atgagactaa tcatctcttc agcattagcg ttatgaatga gtaatataaa tcgataatac
    88321 cgccgctggg atatcgcgta ttttcaccca ttgacaatgt ttttggcggt ggcatgatgc
    88381 gcatgaaatt tgaacttcct cacggtttta attcatgtcc acgtataccc ggcctgtcat
    88441 gcttttgctg tctggcctgc ttttgttgac tctggcgatt gcggtgttaa atacactcgt
    88501 gccgctttgg ctcgcccagg aacacatgtc cacatggcag gtaggcgttg tcagctcatc
    88561 ctattttacc ggcaaccttg tcggtacatt gctgacaggg tatgtcatta aacgcattgg
    88621 ctttaaccgc agctattatc tggcctcctt catttttgcc gctggctgtg ccggccttgg
    88681 cctgatgatt ggtttctgga gctggttggc gtggcgtttt gtcgctggcg tcggctgtgc
    88741 catgatttgg gtggttgttg agagcgcgct gatgtgcagt gggacgtcac gtaaccgtgg
    88801 gcgtttgctt gctgcataca tgatggttta ttacgtggga acgtttttag gccagttact
    88861 ggtcagcaag gtctcaaccg agctgatgag cgtattgccg tgggttacag gtttgacatt
    88921 ggcagggatc ttaccgctgt tgtttacgcg tgtgctgaat cagcaggctg aaaaccatga
    88981 ttcgacgtca attacggcaa tgctaaaact ccgtcaggcg cggcttggcg tgaatggctg
    89041 cattatctca ggaatcgttc tgggatctct atatggcctg atgccgttgt acctcaatca
    89101 caaaggggtg agcaatgcca gtattggttt ctggatggcg gtactggtca gtgcgggtat
    89161 cctcggacaa tggccgattg gacgtctggc ggataagttt ggtcgactgc tggtgttgcg
    89221 tgttcaggtc tttgtcgtca ttctcggcag tatcgcgatg cttagccagg cggcgatggc
    89281 ccctgcgtta ttcatcctcg gtgccgctgg ctttacgcta tatccggtgg cgatggcctg
    89341 ggcttgtgag aaagttgaac atcatcaact ggtggcgatg aaccaggcct tactgttgag
    89401 ctataccgtg ggaagtctgc ttggcccgtc atttaccgct atgctaatgc agaatttctc
    89461 cgataattta ttgtttatca tgatcgccag cgtatcgttt atctatttgc tgatgctgct
    89521 gcgcaacgcc ggtcatacgc cgaaacccgt tgctcacgtg taaatgaatt caagcagagt
    89581 gtgaacttac tgtttcacac tctgcttttt tgtttcttct atctgacttg ctttattcca
    89641 aattttattc gtttaaaaat aaaatgtgca gcaggttata attttgcatt tcgctatttc
    89701 cgcacttctt atttgccgcg cataatccca cgttttacag atgccccttt aattttggcg
    89761 aaggatttgt ctatggctgg gaatgttcag gaaaaacagc tgcgatggta caacattgcg
    89821 ctgatgtctt ttatcactgt ctggggtttt ggcaacgttg ttaataacta tgccaaccag
    89881 gggctggtgg ttgttttttc atgggtgttt atctttgcac tctatttcac accttatgcg
    89941 ctaattgttg gtcagttagg ctcgaccttc aaagatggga agggcggggt cagtacctgg
    90001 attaaacaca cgatgggacc cggactggct tatctcgccg cgtggaccta ctgggtggtg
    90061 catattccct atctggcaca aaaaccccag gcaattctga ttgcgctcgg ttgggcgatg
    90121 aaaggcgacg gttcgctaat caaagaatat tcagtcgtag cgttacaggg gttaacgctg
    90181 gtgctgttta tcttctttat gtgggttgct tcacgcggta tgaaatcgct gaaaatcgtc
    90241 ggttctgtgg cagggattgc gatgtttgtt atgtcgctcc tgtatgtggc gatggcggta
    90301 accgcgcctg cgattactga agtgcatatt gcgaccacaa acattacctg ggaaacgttc
    90361 attcctcata tcgactttac ctacattacc actatttcaa tgctggtttt cgcggttggc
    90421 ggagcagaga agatttctcc ttacgttaat caaacgcgca acccaggaaa agaatttcca
    90481 aaagggatgc tatgcctggc ggtgatggtt gcggtttgtg ccattctggg ctcactggcg
    90541 atggggatga tgtttgactc gcgtaatatc ccggatgact taatgactaa cggtcaatat
    90601 tacgcctttc agaagctggg cgagtattac aacatgggta atactttaat ggtgatttac
    90661 gccattgcga ataccctggg acaagtagct gcgctggtat tctcgattga tgccccgctt
    90721 aaagtgctat taggtgatgc tgacagcaaa tatattccag ccagtttatg tcgtaccaac
    90781 gcttctggta cgcccgttaa tggctatttt ctgaccctgg tgctggtggc aattctgatt
    90841 atgctgccga ctctcggcat cggtgatatg aacaatctct ataaatggct gttgaatctt
    90901 aactcggtag tgatgccgct gcgttattta tgggtatttg ttgcatttat tgcagtcgtt
    90961 cgcctggcgc agaaatataa accagaatat gtctttattc gtaataagcc tctggcaatg
    91021 accgtcggga tttggtgttt tgcctttacc gcctttgcct gtttgacggg gatcttcccg
    91081 aaaatggaag ccttcactgc agagtggacc ttccagttgg cgctgaatgt tgcaacgccg
    91141 tttgtgctgg taggattagg actgattttc ccgctgctgg cgcgtaaagc gaatagtaaa
    91201 taattattgt ggtcggtgac gctgactctg gcagatctga cccgttttta cataatcgag
    91261 aaatgcgcgc aagccgcagg acatatactg gcggtttgga taatagatct ggaagcctgg
    91321 acgctctgtg ctccagtctt ccagtacaca ttctaaacga ccagtatcaa ggtactcctt
    91381 gatctgttca tagagcagat acccgatacc agcacccatc aaaacggcct ccagttcagc
    91441 atcaacatca tccagaatga tatttcctgc gacagcaatt tccagctcct ttgcaaattg
    91501 ccagtggaaa ggtttgccgc tgggataacg aaaaacaaca cattgatgat taagcagatc
    91561 atgaggatgg cggggtttgc catatcttgc aaagtactct ggcgttgctg ctacacataa
    91621 tttcactggc gggccgatcg ccacgctgat catatctttt tcgacgatgc cactaagtcg
    91681 aacgccagcg tcaaagccct gttggacgat atcgacaaga gagtcgtcag ttgtgagctc
    91741 gactttaata tcaggatatt cacgtgtgaa accaaccagt aaaggcatta aaaatatacg
    91801 tgcagctacc cgggcggcat tgattttgag cgttcctgtc ggtgtcagac gaaaatcatt
    91861 catctcatct aacatgatct gaatttcgtc gaaagctggg cgcaattgtt catagagatt
    91921 agaacccgct tccgttaacg atacgcttcg ggttgtccga ttgaataagc gaattttaag
    91981 acgttgttcc agtgttttaa tactatggct aatggcggac gaggataagc ctaattcatc
    92041 gcccgctgca cgaaagcttt gattacgggc cacggcaaag aaagtggcaa agtcagacat
    92101 attcatccgc attagtgaaa atccttcatt aactcatcct gaatcatcac gtttacagga
    92161 ttatgccgcc tgcgtaaagt gcgctccaga acttaacgtg gaggtaaaat tatgcagtct
    92221 gaacgtattt atttggtatg ggcccatcct cgtcatgatt cattgaccgc acatattgct
    92281 gatgcgatcc atcagcgggc aatggagcgg aaaatacagg tgacggaact cgatttatat
    92341 cggcgtaatt tcaacccggt gatgacgtcg gaagatgaac cagactggaa gaatatggat
    92401 aaacgttatt ctccagaggt tcatcagctt tattcagagc tgcttgagca tgacacgtta
    92461 gtggtggttt ttcctctctg gtggtacagc ttcccggcaa tgctaaaagg atatattgac
    92521 agagtatgga ataatgggct ggcttatgga gatgggcaca aattaccatt caataaagtt
    92581 cgttgggtgg cgctggttgg aggagacaaa gaatcatttg tccagatagg ctgggaaaaa
    92641 aatataagcg attatttaaa aaatatgtgc agttatcttg gtattgaaga tgccgatgtc
    92701 actttcttgt gtaatacagt ggtattcgat ggggaagaac ttcacgcgag ctattatcag
    92761 tcgttattat ctcaggtacg ggatatggta gatgcactat aagatgtgtt aaaaacgctg
    92821 tagcagaatg aagtgcggaa taaaaaagcg gcaactcaat aaagttgccg ctttacgggg
    92881 aaattagaac attaccttat gaccgtactg ctcaagaatg cctttcacgc gttccatggt
    92941 ctctttcttc ggtggtttaa caccgtcgag tttgtactct tcacccattg ccacccattt
    93001 gtgtttgccc agctcgtggt aggggagaag ctcgattttc tcaacgttgc ccatatcacg
    93061 ggtaaattca ccgaggcgat gcgctgaatc gtcatcgtca gaccagcctg ggacaacaac
    93121 gtagcggatc cacaccttca catttttgtt cgccagatat ttggcgaact ccagcgtgcg
    93181 gtgattggaa actccaacca gattttggtg gatctcgtcg ttcatctgtt tgagatcgag
    93241 cattaccagg tcggttactt ccagcagttc atcaatcacc ggatcgtaac gacgaacaaa
    93301 accgttggtg tccagacagg tatgaatgcc ttcttttttg caggcgcgga accagtcacg
    93361 aacaaactca gcttgtagga ttgcctcacc gccggatgcg gtaacgccgc cgccggaagc
    93421 gttcataaag tggcgatagg tcaccacctc tttcattaaa tcttcaacgg taacttcttt
    93481 accgccatgc gtatcccagg tgtcgcggtt atgacaatac aggcagcgca tcaggcagcc
    93541 ctggaaaaag gtgataaagc gaatacctgg gccgtctacg gttccacagg attcaaagga
    93601 gtgaatgcga ccaataactg acattgcggt gtttctccag atgtggccca tctgaggccg
    93661 tgttggtgcg cagctcgaag gctacgtcga gtctgttttg gcagtcacct taaagtatag
    93721 atagctgaca aaaaaggctc tcgtgctaaa aaaggcccca ctttcgtgga gcctttattg
    93781 tacgcttttt actgtacgat ttcagtcaaa tctaattaca tagattgagt gaaggtacga
    93841 gtaataacgt cctgctgctg ttctttagtc agcgagttga aacgtactgc gtagccagat
    93901 acacggatgg tcagctgcgg atatttttcc gggttttcca tcgcgtcgag cagcatttca
    93961 cggttcatca cgttaacgtt caggtgctga ccaccttcga tggatgcttc gtggtggaag
    94021 taaccatcca tcagaccagc caggttggtc ttacgaactt cgtcgtcttt acccagtgcg
    94081 ttcggaacga tagagaaggt gtaggagata ccatctttag cgtaagcaaa cggcagttta
    94141 gcaacggaag tcagagacgc tacagcacct ttctggtcac gaccgtgcat cgggttagca
    94201 cccggtccga acggcgcgcc agcacgacga ccgtctgggg tgttaccagt tttcttacca
    94261 tacacaacgt tagaagtgat ggtcagaaca gactgagtcg ggatagcgtc acggtaggtg
    94321 tgcagtttct gaattttctt catgaaacgt tctaccaggt caacagccag gtcatctaca
    94381 cgcggatcat tgttaccaaa ctgcgggtat tcgccttcga tttcgaagtc gatagccaga
    94441 ccgtcttcgt cacgaatcgg tttaactttc gcatatttga ttgcagacag ggagtcagca
    94501 gcaacggaca gaccagcgat accacacgcc atggtgcgga taacgtcacg gtcgtgcagc
    94561 gccatcagag aggcttcgta gctgtacttg tcgtgcatgt agtggatgat gttcagtgca
    94621 gtgatgtact gtttagccag ccagtccatg aagtgatcca tgcgctccat cacttcatca
    94681 tagttcagga catcgccttt gatcggttca gacttcggac caacctgcat tttcagtttt
    94741 tcgtcaacgc cgccgttgat tgcgtacagc atggttttcg ccaggtttgc acgcgcaccg
    94801 aagaactgca tttgtttacc aacgatcatc gggcttacgc agcaagcaat agcgtagtca
    94861 tcgttgttga agtccggacg catcaggtca tcgttctcat actgcagaga agaggtgtcg
    94921 atggacactt tagcggcgaa tttcttgaag ttcagcggca gtttttcaga ccacagaatg
    94981 gtcatgttcg gttccggaga cggacccatg gtgtacaggg tgttcaggaa acggaagctg
    95041 tttttggtaa ccagggtacg accgtcgagg cccataccac cgatagattc ggttgcccag
    95101 atcgggtcgc cagagaacag ttcatcgtat tccggagtac gcaggaagcg aaccatacgc
    95161 agtttcatga ccaggtggtc aaccatttcc tgcgcttctt gttcggtgat cttgccagct
    95221 ttcaggtcac gttcgatgta cacatccagg aaggtggagg tacgaccgaa ggacattgca
    95281 gcaccgttct gagacttaac agcagccagg tagccgaagt aagtccactg gatagcttcc
    95341 tgagcgttgg tagccggacc agagatgtcg tagccgtatt tcgcagccat ttctttcatc
    95401 tgacccagag cgcggtgctg ttcagcgatt tcttcgcgca gacggatagt ctgttccagg
    95461 tttacgccgt tttccagatc agcctgcaga gaagtgaact gtgccagttt gtctttcatc
    95521 aggtagtcga taccgtacag cgcaacgcga cggtagtcac cgatgatacg gccacggcca
    95581 tatgcatctg gcagaccggt cagaacacca gatttacggc aacgcaggat gtccggagtg
    95641 taaacgtcga acacgccctg gttgtgagtt ttacggtatt cagtgaagat ttttttgatc
    95701 atcggatcca gttcgcggtt gtacgctttg caggaacctt cgatcatttt gataccaccg
    95761 aacgggataa gagcacgttt cagcggagct tcagtctgca gaccaacgat tttctcaagc
    95821 tgcttgttga tgtagccagc gtcgtgagag gtgatggtgg aagcaacagc ggtgtcaaag
    95881 tcaactggcg cgtgagtgcg gttttccagt ttaacgcctt ccattacttt gtcccacagg
    95941 gtggtggtcg cttcagtagc gccagccagg aaggactcgt caccctcgta cggagtgtag
    96001 tttttctgaa tgaagtcacg gacgtttact tcattctgcc agtcaccttt ggtaaaacct
    96061 tcccaggctg tggctaactt ttcattaagc tcggacatgt aacacctacc ttcttaagtg
    96121 gattttttat ttactgcgta cttcgacaac cattaatggt gatcgttttc acgcaggtaa
    96181 atgacccagt atgtcaaccc aaccaacaaa ccaccgccga taatattacc gatcgtaacc
    96241 ggaatcaggt tatcagtgat gaagttcatc acggtcaggt gagaaaaatt ttccggtgca
    96301 gaaccgacag cggtccagaa ttccggagat gcgaagtcgc ggattacaat acccatcggg
    96361 atcataaaca tgtttgcgat actgtgctca aaaccgctgg caacaaacat cgcgaccggc
    96421 agcaccataa tgaacgcttt gtccatcagg ctacggccag aataactcat ccatactgcc
    96481 agacatacca tcaggtttgc caggatacca aggcagacgg cctcaataaa agtatggtgc
    96541 actttgtggt cggcggtttg taggacgttt agtccccatt gaccatttgc ggtcatatac
    96601 tcgccggaaa gccacattaa aagtacaaac agcagtgcgc cgaccaggtt gccaaaatag
    96661 acatttagcc agtttttcgc caactgaccc caggtgatgc gcccactcgc cttagcaaca
    96721 acaatcaaca ctgtggaagt aaagagatcg gctccgcaga caacacaaag aatcagcccc
    96781 agagagaagc aaatgccgcc aaccagtttt gccatgccga agggcattgt gcctgtgcca
    96841 gtggttgctg tgatatagaa gacgaatgcg attgagatga aaacaccggc ggtaatcgcc
    96901 agatagaaag tcttaagcgg atgtttcgtt gctttataga cacccgcctc ttcggccact
    96961 ttggccattg cagcaggaag taaaagatca aaagggttgt cagctttcac actaactctc
    97021 tctttattaa gtcggcgacg agatactaac aaagcattat agatgagaaa ttgatataga
    97081 tcatatctcg cctggcttat agg
//
LOCUS       DAPGUL010000003        96068 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.003, whole genome shotgun sequence.
ACCESSION   DAPGUL010000003 DAPGUL010000000
VERSION     DAPGUL010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 96068)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 96068)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..96068
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.003"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            132..2375
                     /gene="pdeF"
                     /locus_tag="RHX21_000183"
     CDS             132..2375
                     /gene="pdeF"
                     /locus_tag="RHX21_000183"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase
                     PdeF"
                     /protein_id="HDV1985429.1"
                     /translation="MKLNATYIKIRDKWWGLPLFLPSLILPIFAHINTFAHISSGEVF
                     LFYLPLALMISMMMFFSWAALPGITLGIFVRKYAELGFYETLSLTANFIIIIILCWGG
                     YRVFTPRRNNVSHGDTRLISQRIFWQIVFPATLFLILFQFAAFVGLLASRENLVGVMP
                     FNLGTLINYQALLVGNLIGVPLCYFIIRVVRNPFYLRSYYSQLKQQVDAKVTKKEFAL
                     WLLALGALLLLLCMPLNEKSTIFSTNYTLSLLLPLMMWGAMRYGYKLISLLWAVVLMI
                     SIHSYQNYIPIYPGYTTQLTITSSSYLVFSFIVNYMAVLATRQRAVVRRIQRLAYVDP
                     VVHLPNVRALNRALRDAPWSALCYLRIPGMEMLVKNYGIMLRIQYKQKLSHWLSPLLE
                     PGEDVYQLSGNDLALRLNTESHQERITALDSHLKQFRFFWDGMPMQPQIGVSYCYVRS
                     PVNHIYLLLGELNTVAELSIVTNAPENMQRRGAMYLQRELKDKVAMMNRLQQALEHNH
                     FFLMAQPITGMRGDVYHEILLRMKGENDELIGPDSFLPVAHEFGLSSSIDMWIIEHTL
                     QFMAENRAKMPAHRFAINLSPTSVCQARFPVEVSQLLDKYQIEAWQLIFEVTESNALT
                     NVKQAQITLQHLQELGCQIAIDDFGTGYASYARLKNVNADLLKIDGSFIRNIVSNSLD
                     YQIVASICHLARMKKMRVVAEYVENEEIREAVLSLGIDYMQGYLIGKPQPLIDTLNEI
                     EPIRESA"
     gene            complement(2414..3955)
                     /gene="ppx"
                     /locus_tag="RHX21_000184"
     CDS             complement(2414..3955)
                     /gene="ppx"
                     /locus_tag="RHX21_000184"
                     /EC_number="3.6.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolyphosphatase"
                     /protein_id="HDV1985430.1"
                     /translation="MPIHDKSPRPQEFAAVDLGSNSFHMVIARVVDGAMQIIGRLKQR
                     VHLADGLGPDNMLSEEAMTRGLNCLSLFAERLQGFSPASVCIVGTHTLRQALNATDFL
                     KRAEKVIPYPIEIISGNEEARLIFMGVEHTQPEKGRKLVIDIGGGSTELVIGENFEPI
                     LVESRRMGCVSFAQLYFPGGVINKENFQRARMAAAQKLETLTWQFRIQGWNVAMGASG
                     TIKAAHEVLMEMGEKDGIITPERLEKLVKEVLRHRNFASLSLPGLSEERKTVFVPGLA
                     ILCGVFDALAIRELRLSDGALREGVLYEMEGRFRHQDVRSRTASSLANQYHIDSEQAR
                     RVLDTTMQMYEQWREQQPKLAHPQLEALLRWAAMLHEVGLNINHSGLHRHSAYILQNS
                     DLPGFNQEQQLMMATLVRYHRKAIKLDDLPRFTLFKKKQFLPLIQLLRLGVLLNNQRQ
                     ATTTPPTLTLITDDSHWTLRFPHDWFSQNALVLLDLEKEQEYWEGVAGWRLKIEEEST
                     PEIAA"
     gene            complement(3960..6026)
                     /gene="ppk1"
                     /locus_tag="RHX21_000185"
     CDS             complement(3960..6026)
                     /gene="ppk1"
                     /locus_tag="RHX21_000185"
                     /EC_number="2.7.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate kinase 1"
                     /protein_id="HDV1985431.1"
                     /translation="MGQEKLYIEKELSWLSFNERVLQEAADKSNPLIERMRFLGIYSN
                     NLDEFYKVRFAELKRRIIISEEQGSNSHSRHLLGKIQSRVLKADQEFDGLYNELLLEM
                     ARNQIFLINERQLSVNQQNWLRHYFKQYLRQHITPILINPDTDLVQFLKDDYTYLAVE
                     IIRGDTIRYALLEIPSDKVPRFVNLPPEAPRRRKPMILLDNILRYCLDDIFKGFFDYD
                     ALNAYSMKMTRDAEYDLVHEMEASLMELMSSSLKQRLTAEPVRFVYQRDMPNALVEVL
                     REKLTISRYDSIVPGGRYHNFKDFINFPNVGKANLVNKPLPRLRHIWFDKAQFRNGFD
                     AIRERDVLLYYPYHTFEHVLELLRQASFDPSVLAIKINIYRVAKDSRIIDSMIHAAHN
                     GKKVTVVVELQARFDEEANIHWAKRLTEAGVHVIFSAPGLKIHAKLFLISRKENGEVV
                     RYAHIGTGNFNEKTARLYTDYSLLTADARITNEVRRVFNFIENPYRPVTFDYLMVSPQ
                     NSRRLLYEMVDREIANAQQGLPSGITLKLNNLVDKGLVDRLYAASSSGVPVNLLVRGM
                     CSLIPNLEGISDNIRAISIVDRYLEHDRVYIFENGGDKKVYLSSADWMTRNIDYRIEV
                     ATPLLDPRLKQRVLDIIDILFSDTVKARYIDKELSNRYVPRGNRRKVRAQLAIYDYIK
                     SLEQPE"
     gene            complement(6197..6835)
                     /gene="purN"
                     /locus_tag="RHX21_000186"
     CDS             complement(6197..6835)
                     /gene="purN"
                     /locus_tag="RHX21_000186"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HDV1985432.1"
                     /translation="MNIVVLISGNGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLE
                     RARQAGIATHTLIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAG
                     RLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGD
                     TEDDITARVQTQEHAIYPLVISWFADGRLKMHENAAWLDGQRLPPQGYAADE"
     gene            complement(6835..7872)
                     /gene="purM"
                     /locus_tag="RHX21_000187"
     CDS             complement(6835..7872)
                     /gene="purM"
                     /locus_tag="RHX21_000187"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HDV1985433.1"
                     /translation="MTDKTSLSYKDAGVDIDAGNALVGRIKGVVKKTRRPEVMGGLGG
                     FGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRHDTIGIDLVAMCVNDLVVQGAEP
                     LFFLDYYATGKLDVDTASAVISGIAEGCLQSGCSLVGGETAEMPGMYHGEDYDVAGFC
                     VGVVEKSEIIDGSKVSDGDVLIALGSSGPHSNGYSLVRKILEVSGCDPQTTELDGKPL
                     ADHLLAPTRIYVKSVLELIEKVDVHAIAHLTGGGFWENIPRVLPDNTQAVIDESSWQW
                     PEVFNWLQTAGNVERHEMYRTFNCGVGMIIALPAPEVDKALALLNANGENAWKIGIIK
                     ASDSEQRVVIE"
     gene            8197..8823
                     /gene="upp"
                     /locus_tag="RHX21_000188"
     CDS             8197..8823
                     /gene="upp"
                     /locus_tag="RHX21_000188"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HDV1985434.1"
                     /translation="MKIVEVKHPLVKHKLGLMREQDISTKRFRELASEVGSLLTYEAT
                     ADLETEKVTIEGWNGPVEIDQIKGKKITVVPILRAGLGMMDGVLENVPSARISVVGMY
                     RNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLV
                     AAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK"
     gene            8909..10198
                     /gene="uraA"
                     /locus_tag="RHX21_000189"
     CDS             8909..10198
                     /gene="uraA"
                     /locus_tag="RHX21_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HDV1985435.1"
                     /translation="MTRRAIGVSERPPLLQTIPLSLQHLFAMFGATVLVPVLFHINPA
                     TVLLFNGIGTLLYLFICKGKIPAYLGSSFAFISPVLLLLPLGYEVALGGFIMCGVLFC
                     LVSFIVKKAGTGWLDVLFPPAAMGAIVAVIGLELAGVAAGMAGLLPAEGQTPDSKTII
                     ISITTLAVTVLGSVLFRGFLAIIPILIGVLVGYALSFAMGIVDTTPIINAHWFALPTL
                     YTPRFEWFAILTILPAALVVIAEHVGHLVVTANIVKKDLLRDPGLHRSMFANGLSTVI
                     SGFFGSTPNTTYGENIGVMAITRVYSTWVIGGAAIFAILLSCVGKLAAAIQMIPLPVM
                     GGVSLLLYGVIGASGIRVLIESKVDYNKAQNLILTSVILIIGVSGAKVNIGAAELKGM
                     ALATIVGIGLSLIFKLISVLRPEEVVLDAEDADITDK"
     gene            10248..10994
                     /gene="hda"
                     /locus_tag="RHX21_000190"
     CDS             10248..10994
                     /gene="hda"
                     /locus_tag="RHX21_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA inactivator Hda"
                     /protein_id="HDV1985436.1"
                     /translation="MVNFSRFCEILVEVSLNTPAQLSLPLYLPDDETFASFWPGDNSS
                     LLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVP
                     EVLDGMEHLSLVCIDNIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNL
                     GLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRT
                     LFMTLDQLDRASITAQRKLTIPFVKEILKL"
     gene            complement(11132..11491)
                     /gene="arsC"
                     /locus_tag="RHX21_000191"
     CDS             complement(11132..11491)
                     /gene="arsC"
                     /locus_tag="RHX21_000191"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311384.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HDV1985437.1"
                     /translation="MTKQVKIYHNPRCSKSRETLNLLKENGVEPEVVLYLETPADAAT
                     LRDLLKMLGMNSARELMRQKEDLYKELNLADSSLSEEALIQAMVDNPKLMERPIVVAN
                     GKARIGRPPEQVLEIVG"
     gene            complement(11512..12975)
                     /gene="bepA"
                     /locus_tag="RHX21_000192"
     CDS             complement(11512..12975)
                     /gene="bepA"
                     /locus_tag="RHX21_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-barrel assembly-enhancing protease"
                     /protein_id="HDV1985438.1"
                     /translation="MFRQLKKNLVATLIAAMTIGQVAPAFADSADTLPDMGTSAGSTL
                     SIGQEMQMGDYYVRQLRGSAPLINDPLLTQYINSLGMRLVSHANSVKTPFHFFLINND
                     EINAFAFFGGNVVLHSALFRYSDNESQLASVMAHEISHVTQRHLARAMEDQQRSAPLT
                     WVGALGSILLAMASPQAGMAALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRSGFD
                     PQAMPTFLEKLLDQARYSSRPPEILLTHPLPESRLADARNRANQMRPMVVQSSEDFYL
                     AKARTLGMYNSGRNQLTSDLLDEWAKGNVRQQRAAQYGRALQAMEANKYDEARKTLQP
                     LLAAEPGNAWYLDLATDIDLGQNKANEAINRLKNARDLRTNPVLQLNLANAYLQGGQP
                     QEAANILNRYTFNNKDDSNGWDLLAQAEAALNNRDQELAARAEGYALAGRLDQAISLL
                     SSASSQVKLGSLQQARYDARIDQLRQLQERFKPYTKM"
     gene            13188..14249
                     /locus_tag="RHX21_000193"
     CDS             13188..14249
                     /locus_tag="RHX21_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDV1985439.1"
                     /translation="MLEMLMQWYRRRFSDPEAIALLVILVAGFGIIFFFSGLLAPLLV
                     AIVLAYLLEWPTVRLQSIGCSRRWATSIVLVVFVGILLLMAFVVLPIAWQQGIYLIRD
                     MPGMLNKLSDFAATLPRRYPALMDAGIIDAMAENMRSRMLTMGDSVVKISLASLVGLL
                     TIAVYLVLVPLMVFFLLKDKEQMLNAVRRVLPRNRGLAGQVWKEMNQQITNYIRGKVL
                     EMIVVGIATWLGFLLFGLNYSLLLAVLVGFSVLIPYIGAFVVTIPVVGVALFQFGAGT
                     EFWSCFAVYLIIQALDGNLLVPVLFSEAVNLHPLVIILSVVIFGGLWGFWGVFFAIPL
                     ATLIKAVIHAWPDGQIAQE"
     gene            complement(14287..15134)
                     /locus_tag="RHX21_000194"
                     /pseudo
     CDS             complement(14287..15134)
                     /locus_tag="RHX21_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311381.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="formate transporter"
     gene            complement(15156..17168)
                     /gene="hyfR"
                     /locus_tag="RHX21_000195"
                     /pseudo
     CDS             complement(15156..17168)
                     /gene="hyfR"
                     /locus_tag="RHX21_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311380.2"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator HyfR"
     gene            complement(17198..17611)
                     /gene="hyfJ"
                     /locus_tag="RHX21_000196"
     CDS             complement(17198..17611)
                     /gene="hyfJ"
                     /locus_tag="RHX21_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416985.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 assembly chaperone HyfJ"
                     /protein_id="HDV1985440.1"
                     /translation="MTEECGEIVFWTLRKKFVASSDEMPEHSSQVMYYSLAIGHHVGV
                     IDCLNVAFRCPLTEYEDWLAQVEEEQARRKMLGVMTFGEIVIDASHTALLTRAFAPLA
                     DDATSVWQARSIQFIHLLDEIVQEPAIYLMARKIA"
     gene            complement(17604..18361)
                     /gene="hyfI"
                     /locus_tag="RHX21_000197"
                     /pseudo
     CDS             complement(17604..18361)
                     /gene="hyfI"
                     /locus_tag="RHX21_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416984.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 catalytic subunit HyfI"
     gene            complement(18358..18903)
                     /gene="hyfH"
                     /locus_tag="RHX21_000198"
     CDS             complement(18358..18903)
                     /gene="hyfH"
                     /locus_tag="RHX21_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit H"
                     /protein_id="HDV1985441.1"
                     /translation="MLKLLKTIMRAGTATVKYPFAPLEVSPGFRGKPDLMPSQCIACG
                     ACACACPANALTIQTDDQQNSRTWQLYLGRCIYCGRCEEVCPTRAIQLTNNFELTVTN
                     KADLYTRATFHLQRCSRCERPFAQQKTVALAAELLAQQQNAPQNREMLWAQASVCPEC
                     KQRATLLNDDTDVPLVAKEQL"
     gene            complement(18913..20580)
                     /gene="hyfG"
                     /locus_tag="RHX21_000199"
     CDS             complement(18913..20580)
                     /gene="hyfG"
                     /locus_tag="RHX21_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 catalytic subunit HyfG"
                     /protein_id="HDV1985442.1"
                     /translation="MNVNSSSNRGEAILAALKTQFPGAVLDEERQTPEQVTITVKINL
                     LPDVVHYLYYQHDGWLPVLFGNDERTLNGHYAVYYALSMEGAEKCWIVVKALVDADSR
                     EFPSVTPRVPAAVWGEREIRDMYGLIPVGLPDQRRLVLPDDWPEDMHPLRKDAMDYRL
                     RPEPTTDSETYAFINEGNSDARVIPVGPLHITSDEPGHFRLFVDGEQIVDADYRLFYV
                     HRGMEKLAETRMGYNEVTFLSDRVCGICGFAHSVAYTNSVENALGIEVPQRAHTIRSI
                     LLEVERLHSHLLNLGLSCHFVGFDTGFMQFFRVREKSMTMAELLIGSRKTYGLNLIGG
                     VRRDILKEQRLQTLKLVREMRADVSELVEMLLATPNMEQRTQGIGILDRQIARDLRFD
                     HPYADYGNIPKTLFTFTGGDVFSRVMVRVKETFDSLAMLEFALDNMPDTPLLTEGFSY
                     KPHAFALGFVEAPRGEDVHWSMLGDNQKLFRWRCRAATYANWPVLRYMLRGNTVSDAP
                     LIIGSLDPCYSCTDRVTLVDVRKRQSKTVPYKEIERYGIDRNRSPLK"
     gene            complement(20570..22150)
                     /gene="hyfF"
                     /locus_tag="RHX21_000200"
     CDS             complement(20570..22150)
                     /gene="hyfF"
                     /locus_tag="RHX21_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit F"
                     /protein_id="HDV1985443.1"
                     /translation="MSYSVMFALLLLTPLLFSLLCFACRKRGLSATCTVTVLHSLGIT
                     LLLILALWVVQTAADAGEIFAAGLWLHIDGLGGLFLAILGVIGFLTGVYSIGYMRHEV
                     AHGELSPVTLCDYYGFFHLFLFTMLLVVTSNNLIVMWAAIEATTLSSAFLVGIYGQRS
                     SLESAWKYIIICTVGVAFGLFGTVLVYANAASVMPQAEMAIFWSEVLKQSSLLDPTLM
                     LLAFVFVLIGFGTKTGLFPMHAWLPDAHSEAPSPVSALLSAVLLNCALLVLIRYYIII
                     CQAIGSDFPNRLLLIFGMLSVAVAAFFILVQRDIKRLLAYSSVENMGLVAVALGIGGP
                     LGIFAALLHTLNHSLAKTLLFCGSGNVLLKYGTRDLNVVCGMLKIMPFTAVLFGGGAL
                     ALAGMPPFNIFLSEFMTVTAGLARNHLLIIVLLLLLLTLVLAGLVRMAARVLMAKPPQ
                     AVNRGDLGWLTTSPMVILLVMMLAMGTHIPQPVIRILAGASTIVLSGTHDLPAQRSTW
                     HDFLPSGTASVSEKHSER"
     gene            complement(22155..22805)
                     /gene="hyfE"
                     /locus_tag="RHX21_000201"
     CDS             complement(22155..22805)
                     /gene="hyfE"
                     /locus_tag="RHX21_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 membrane subunit"
                     /protein_id="HDV1985444.1"
                     /translation="MTGSMIVNNLAGLMMLTSLFVISVKSYRLSCGFYACQSLVLVSI
                     FATLSCLFAAEQLLIWSASAFITKVLLVPLIMTYAARNIPQNIPEKALFGPAMMALLA
                     ALIVLLCAFVVQPVKLPMATGLKPALAVALGHFLLGLLCIVSQRNILRQIFGYCLMEN
                     GSHLVLALLAWRAPELVEIGIATDAIFAVIVMVLLARKIWRTHGTLDVNNLTALKG"
     gene            complement(22817..24048)
                     /locus_tag="RHX21_000202"
                     /pseudo
     CDS             complement(22817..24048)
                     /locus_tag="RHX21_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416979.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit D"
     gene            complement(24065..25012)
                     /gene="hyfC"
                     /locus_tag="RHX21_000203"
     CDS             complement(24065..25012)
                     /gene="hyfC"
                     /locus_tag="RHX21_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416978.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit HyfC"
                     /protein_id="HDV1985445.1"
                     /translation="MRQTLCDGYLVIFALAQAVILLMLTPLFTGISRQIRARMHSRRG
                     PGIWQDYRDIHKLFKRQEVAPTSSGLMFRLMPWVLISSMLVLAMALPLFITVSPFAGG
                     GDLITLIYLLALFRFFFALSGLDTGSPFAGVGASRELTLGILVEPMLILSLLVLALIA
                     GSTHIEMISNTLAMGWNSPLTTVLALLACGFACFIEMGKIPFDVAEAEQELQEGPLTE
                     YSGAGLALAKWGLGLKQVVMASLFVALFLSFGRAQELSLACLLTSLVVTLLKVLLIFV
                     LASIAENTLARGRFLLIHHVTWLGFSLAALAWVFWLTGL"
     gene            complement(25023..27041)
                     /gene="hyfB"
                     /locus_tag="RHX21_000204"
     CDS             complement(25023..27041)
                     /gene="hyfB"
                     /locus_tag="RHX21_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit B"
                     /protein_id="HDV1985446.1"
                     /translation="MDALQLLTWSLILYLFASLASLFLLGLDRLAIKLSGITSLVGGV
                     IGIISGITQLHAGVTLVAHFATPFDFADLTLRMDSLSAFMVLVISLLVVVCSLYSLTY
                     MREYEGKGAAAMGFFMNLFIASMVALLVMDNAFWFIVLFEMMSLSSRFLVIARQDKTS
                     INAGMLYFFIAHAGSVLIMIAFLLMGRESGSLDFASFRTLSLSPGLASAVFLLAFFGF
                     GAKAGMMPLHSWLPRAHPAAPSHASALMSGVMVKIGIFGILKVAMDLLAQTGLPLWWG
                     ILVMAIGAISALLGVLYALAEQDIKRLLAWSTVENVGIILLAVGVAMVGLSLHDPLLT
                     VVGLLGALFHLLNHALFKGLLFLGAGAIISRLHTHDMEKMGALAKRMPWTAAACLIGC
                     LAISAIPPLNGFISEWYTWQSLFSLSRVEAVALQLAGPIAMVMLAVTGGLAVMCFVKM
                     YGITFCGAPRSTHAEEAQEVPNTMIVAMLLLAALCVLIALSASWLAPKIMHIAHAFTN
                     TPPVTVASGIALVPGTFHTQVTPSLLLLLLLAMPLLPGLYWLWCRSRRAAFRRTGDAW
                     ACGYGWENAMAPSGNGVMQPLRVVFSALFRLRQQLDPTLRLNKGFAHVTARAQSTEPF
                     WDERVIRPIVSATQRLAKEIQHLQSGDFRLYCLYVVAALVVLLIAIAV"
     gene            complement(27041..27658)
                     /gene="hyfA"
                     /locus_tag="RHX21_000205"
     CDS             complement(27041..27658)
                     /gene="hyfA"
                     /locus_tag="RHX21_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit HyfA"
                     /protein_id="HDV1985447.1"
                     /translation="MNRFVVAEPLWCTGCNTCLAACSDVHKTQGLQQHPRLALAKTST
                     ITAPVVCHHCEEAPCLQVCPVNAISQRDDAIQLNESLCIGCKLCAVVCPFGAISASGS
                     RPVNAHAQYVFQAEGSLKDGEENVLPQHALLRWEPGVQTVAVKCDLCDFLPEGPACVR
                     ACPNQALRLITDDSLQRQMKEKQRLAASWFANGGEDPLSLTQEQH"
     gene            complement(27911..28381)
                     /gene="bcp"
                     /locus_tag="RHX21_000206"
     CDS             complement(27911..28381)
                     /gene="bcp"
                     /locus_tag="RHX21_000206"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HDV1985448.1"
                     /translation="MNPLKAGDIAPKFSLPDQDGEQVNLTDFQGQRVLVYFYPKAMTP
                     GCTVQACGLRDNMDELKKAGVDVLGISTDKPEKLSRFAEKELLNFTLLSDEDHQVCEQ
                     FGVWGEKSFMGKTYDGIHRISFLIDADGKIEHVFDDFKTSNHHDVVLNWLKEHA"
     gene            complement(28381..28953)
                     /locus_tag="RHX21_000207"
     CDS             complement(28381..28953)
                     /locus_tag="RHX21_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system transcriptional
                     repressor"
                     /protein_id="HDV1985449.1"
                     /translation="MTLSSQHYLVITALGADRPGIVNTITRHVSSCGCNIEDSRLAML
                     GEEFTFIMLLSGSWNAITLIESTLPLKGAELDLLIVMKRTTARPRPPMPASVWVQVDV
                     ADSPHLIERFTALFDAHHMNIAELVSRTQPAENERAAQLHIQITAHSPASADAANIEQ
                     AFKALCTELNAQGSINVVNYSQHDEQDGVK"
     gene            29099..29977
                     /gene="dapA"
                     /locus_tag="RHX21_000208"
     CDS             29099..29977
                     /gene="dapA"
                     /locus_tag="RHX21_000208"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001311023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDV1985450.1"
                     /translation="MFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGT
                     TGESATLNHDEHADVVMMTLELADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLT
                     VTPYYNRPSQEGLYQHFKAIAEHTDLPQILYNVPSRTGCDLLPETVGRLAKVKNIIGI
                     KEATGNLTRVNQIKELVSDDFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMC
                     KLAAEGHFAEARVINQRLMPLHNKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITD
                     SGRETVRAALKHAGLL"
     gene            29994..31028
                     /gene="bamC"
                     /locus_tag="RHX21_000209"
     CDS             29994..31028
                     /gene="bamC"
                     /locus_tag="RHX21_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708316.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamC"
                     /protein_id="HDV1985451.1"
                     /translation="MAYSVQKSRLAKVAGVSLVLLLAACSSDSRYKRQVSGDEAYLEA
                     APLAELHAPAGMILPVTSGDYAIPVTNGSGAVGKALDIRPPAQPLALVSGARTQFTGD
                     TASLLVENGRGNTLWPQVVSVLQAKNYTITQRDDAGQTLTTDWVQWNRLDEDEQYRGR
                     YQISVKPQGYQQAVTVKLLNLEQAGKPVADAASMQRYSTEMMNVISAGLDKSATDAAN
                     AAQNRASTTMDVQSATDDTGLPMLVVRGPFNVVWQRLPAALEKVGMKVTDSTRSQGNM
                     AVTYKPLSDSDWQELGASDPGLASGDYKLQVGDLDNRSSLQFIDPKGHTLTQSQNDAL
                     VAVFQAAFSK"
     gene            31241..31954
                     /gene="purC"
                     /locus_tag="RHX21_000210"
     CDS             31241..31954
                     /gene="purC"
                     /locus_tag="RHX21_000210"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDV1985452.1"
                     /translation="MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFD
                     RKGMVNNKFNYFIMSKLAEAGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLV
                     KRLGIEEGIELNPPLFDLFLKNDAMHDPMVNESYCETFGWVSKENLARMKELTYKAND
                     VLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLEKMDKDRFRQSL
                     GGLIEAYEAVARRLGVQLD"
     gene            32108..32335
                     /gene="vapB"
                     /locus_tag="RHX21_000211"
     CDS             32108..32335
                     /gene="vapB"
                     /locus_tag="RHX21_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system antitoxin VapB"
                     /protein_id="HDV1985453.1"
                     /translation="METTVFLSNRSQAVRLPKAVALPEDVKKVEIIAIGRTRIITPAG
                     ESWDSWFDGENVSADFMDIRDQPAMQERESF"
     gene            32335..32733
                     /gene="vapC"
                     /locus_tag="RHX21_000212"
     CDS             32335..32733
                     /gene="vapC"
                     /locus_tag="RHX21_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(fMet)-specific endonuclease VapC"
                     /protein_id="HDV1985454.1"
                     /translation="MLKFMLDTNICIFTIKNKPVHVRERFNLNSGRMCISSVTLMELI
                     YGAEKSQMPERNLAVIEGFVSRLVVLDYDSAAATHTGQIRAELARQGRPVGPFDQMIA
                     GHARSRGLIVVTNNTREFERVAGIRLEDWS"
     gene            32880..33743
                     /locus_tag="RHX21_000213"
     CDS             32880..33743
                     /locus_tag="RHX21_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HDV1985455.1"
                     /translation="MRWQGRRESDNVEDRRNSSGGPSMGGPGFRLPSGKGGLILLLVV
                     LVAGYYGVDLTGLMTGQPVSQQQSTRSISPNEDEAAKFTSVILATTEDTWGQQFEKMG
                     KTYQQPKLVMYRGMTRTGCGAGQSIMGPFYCPADGTVYIDLSFYDDMKDKLGADGDFA
                     QGYVIAHEVGHHVQKLLGIEPKVRQLQQNATQAEVNRLSVRMELQADCFAGVWGHSMQ
                     QQGVLETGDLEEALNAAQAIGDDRLQQQSQGRVVPDSFTHGTSQQRYSWFKRGFDSGD
                     PAQCNTFGKSI"
     gene            33758..35773
                     /gene="tmcA"
                     /locus_tag="RHX21_000214"
     CDS             33758..35773
                     /gene="tmcA"
                     /locus_tag="RHX21_000214"
                     /EC_number="2.3.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA cytosine(34) acetyltransferase TmcA"
                     /protein_id="HDV1985456.1"
                     /translation="MAELTALHTLTAQMKREGIRRLLVLSGEEGWCFDHALKLRDALP
                     GDWLWISPQPDAENHCSPSALQTLLGREFRHAVFDARHGFDAAAFAALSGTLKAGSWL
                     VLLLPVWEEWENQPDADSLRWSDCPDPIATPHFVQHLKRVLTADNDAILWRQNQPFSL
                     AHFTPRTDWHPATGAPQPEQQQLLQQLLTMPPGVAAVTAARGRGKSALAGQLISRIAG
                     SAIVTAPAKAATDVLAQFAGEKFRFIAPDALLASDEQADWLVVDEAAAIPAPLLHQLV
                     SRFPRTLLTTTVQGYEGTGRGFLLKFCARFPHLHRFELQQPIRWAQGCPLEKMVSEAL
                     VFDDENFTHTPQGNIVISAFEQTLWRSEPETPLKVYQLLSGAHYRTSPLDLRRMMDAP
                     GQHFLQAAGENEIAGALWLVDEGGLSQQLSQAVWAGFRRPRGNLVAQSLAAHGSNPLA
                     ATLRGRRVSRIAVHPARQREGTGQQLIAGALQYTRDLDYLSVSFGYTGELWRFWHRCG
                     FVLVRMGNHREASSGCYTAMALLPMSDAGKQLAEREHYRLRRDAQALAQWNGETLPVD
                     PLNDIVLSDDDWLELAGFAFAHRPLLTSLGCLLRLLQTSELALPALRGRLQKNASDAQ
                     LCTTLKLSGRKMLLVRQREEAAQALCALNDVRTERLRDRITQWQFFH"
     gene            35847..36545
                     /gene="ypfH"
                     /locus_tag="RHX21_000215"
     CDS             35847..36545
                     /gene="ypfH"
                     /locus_tag="RHX21_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416968.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HDV1985457.1"
                     /translation="MKHDHFVVQSPDKPAQQLLLLFHGVGDNPVAMGEIGSWFAPLFP
                     DALVVSVGGAEPSGNPAGRQWFSVQGITEDNRQARVDAIMPTFIETVRYWQKQSGVGA
                     NATALIGFSQGAIMVLESIKAEPGLASRVIAFNGRYASLPETASTATTIHLIHGGEDP
                     VIDLAHAVAAQEALISAGGDVTLDIVEDLGHAIDNRSMQFALDHLRYTIPKHYFDEAL
                     SGGKPGDDDVIEMM"
     gene            complement(36655..36855)
                     /locus_tag="RHX21_000216"
     CDS             complement(36655..36855)
                     /locus_tag="RHX21_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpfN family protein"
                     /protein_id="HDV1985458.1"
                     /translation="MDWLAKYWWILVIVFLVGVLLNVIKDLKRVDHKKFLANKPELPP
                     HRDFNDKWDDDDDWPKKDQPKK"
     gene            complement(36883..38010)
                     /gene="dapE"
                     /locus_tag="RHX21_000217"
     CDS             complement(36883..38010)
                     /gene="dapE"
                     /locus_tag="RHX21_000217"
                     /EC_number="3.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020078199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinyl-diaminopimelate desuccinylase"
                     /protein_id="HDV1985459.1"
                     /translation="MSCPVIELTQQLIRRPSLSPDDAGCQALLIERLQAIGFTVERMD
                     FADTQNFWAWRGQGETLAFAGHTDVVPPGDADRWINPPFEPTIRDGMLFGRGAADMKG
                     SLAAMVVAAERFVAQHPNHTGRLAFLITSDEEASAHNGTVKVVEALMARNERLDYCLV
                     GEPSSIEVVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPFLNELVAIE
                     WDQGNEFFPATSMQIANIQAGTGSNNVIPGELFVQFNFRFSTELTDEMIKAQVLALLE
                     KHQLRYTVDWWLSGQPFLTARGKLVDAVVNAVEHYNEIKPQLLTTGGTSDGRFIARMG
                     AQVVELGPVNATIHKINECVNAADLQLLARMYQRIMEQLVA"
     gene            complement(38014..38370)
                     /locus_tag="RHX21_000218"
     CDS             complement(38014..38370)
                     /locus_tag="RHX21_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsC family reductase"
                     /protein_id="HDV1985460.1"
                     /translation="MVTLYGIKNCDTIKKARRWLEANNIDYRFHDYRVDGLDSELLNG
                     FINELGWEALLNTRGTTWRKLDETTRNKITDAASAAALMTEMPAIIKRPLLCAPGKPM
                     LLGFSDSSYQQFFHEV"
     gene            38751..38810
                     /gene="ypfM"
                     /locus_tag="RHX21_000219"
     CDS             38751..38810
                     /gene="ypfM"
                     /locus_tag="RHX21_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YpfM"
                     /protein_id="HDV1985461.1"
                     /translation="MIERELGNWKDFIEVMLRK"
     gene            complement(38909..42022)
                     /gene="acrD"
                     /locus_tag="RHX21_000220"
     CDS             complement(38909..42022)
                     /gene="acrD"
                     /locus_tag="RHX21_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease AcrD"
                     /protein_id="HDV1985462.1"
                     /translation="MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVR
                     VTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSGTGQASVTLSFKAGTDPDE
                     AVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS
                     NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQ
                     LGGTPSVDKQALNATINAQSLLQTPEQFRDITLRVNQDGSEVRLGDVATVEMGAEKYD
                     YLSRFNGKPASGLGVKLASGANEMATAELVLNRLDELAQYFPHGLEYKVAYETTSFVK
                     ASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNT
                     LTMFAMVLAIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLS
                     AVFVPMAFFGGTTGAIYRQFSITIVAAMVLSVLVAMILTPALCATLLKPLKKGEHHGQ
                     KGFFAWFNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRLPTSFLPLE
                     DRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYFTHEKDNIMSVFATVGSGPGGNGQNVA
                     RMFIRLKDWSERDSKTGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDME
                     LQDHAGAGHDALMAARNQLLALAAENPELTRVRHNGLDDSPQLQIDIDQRKAQALGVD
                     IDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVP
                     FSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLE
                     WTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLAT
                     WMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEATLHACRQRLRPI
                     LMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRF
                     PLKPRPE"
     gene            complement(42186..43886)
                     /gene="narQ"
                     /locus_tag="RHX21_000221"
     CDS             complement(42186..43886)
                     /gene="narQ"
                     /locus_tag="RHX21_000221"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite two-component system sensor
                     histidine kinase NarQ"
                     /protein_id="HDV1985463.1"
                     /translation="MIVKRPVSASLARAFFYIVLLSILSTGIALLTLASSLRDAEAIN
                     IAGSLRMQSYRLGYDLQSGSPQLNAHRQLFQQALHSPVLTNLNVWYVPEAVKTRYAHL
                     NANWLEMNNRLSKGDLPWYQANINNYVNQIDLFVLALQHYAERKMLLVVAISLAGGIG
                     IFTLVFFTLRRIRHQVVAPLNQLVTASQRIEHGQFDSPPLDTSLPNELGLLAKTFNQM
                     SSELHKLYLSLEASVEEKTRDLHEAKRRLEVLYQCSQALNTSQIDVHCFRHILQIVRD
                     NEAAEYLELNVGENWRISEGQPNPELPMQILPVTMQETVYGELHWQNSHVSSSEPLLN
                     SVSSMLGRGLYFNQAQKHFQQLLLMEERATIARELHDSLAQVLSYLRIQLTLLKRSIP
                     EDNATAQSIMADFSQALNDAYRQLRELLTTFRLTLQQADLPSALREMLDTLQNQTSAK
                     LTLDCRLPTLALDAQMQVHLLQIIREAVLNAMKHANASEIAVSCVTAPDGNHTVYIRD
                     NGIGIGEPKEPEGHYGLNIMRERAERLGGTLTFSQPSGGGTLVSISFRSAEGEESQLM
                     "
     gene            44092..46071
                     /gene="aegA"
                     /locus_tag="RHX21_000222"
     CDS             44092..46071
                     /gene="aegA"
                     /locus_tag="RHX21_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent uric acid utilization protein
                     AegA"
                     /protein_id="HDV1985464.1"
                     /translation="MNRFIMANSQQCLGCHACEIACVMAHNDEQHVLSQHHFHPRITV
                     IKHQQQRSAVTCHHCEDAPCARSCPNGAISHVDDSIQVNQQKCIGCKSCVVACPFGTM
                     QIVLTPVAAGKVKATAHKCDLCAGRENGPACVENCPADALQLVTDVALSGMAKSRRLR
                     TARQEHQPWHASTAAQEMPVMSKVEQMQATPARGEPDKLAIEARKTGFDEIYLPFRAD
                     QAQREASRCLKCGEHSVCEWTCPLHNHIPQWIELVKAGNIDAAVELSHQTNTLPEITG
                     RVCPQDRLCEGACTIRDEHGAVTIGNIERYISDQALAKGWRPDLSHVTKVDKRVAIIG
                     AGPAGLACADVLTRNGVAVTVYDRHPEIGGLLTFGIPSFKLDKSLLARRREIFSAMGI
                     HFELNCEVGKDVSLDSLLEQYDAVFVGVGTYRSMKAGLPNEDAPGVYDALPFLIANTK
                     QVMGLEELPEEPFINTAGLNVVVLGGGDTAMDCVRTALRHGASNVTCAYRRDEANMPG
                     SKKEVRNAREEGANFEFNVQPVALELNEQGHVCGIRFLRTRLGEPDAQGRRRPVPIEG
                     SEFVMPADAVIMAFGFNPHGMPWLESHGVTVDKWGRIIADVESQYRYQTTNPKIFAGG
                     DAVRGADLVVTAMAEGRHAAQGIIDWLGVKSVKSH"
     gene            46139..46714
                     /gene="nudK"
                     /locus_tag="RHX21_000223"
     CDS             46139..46714
                     /gene="nudK"
                     /locus_tag="RHX21_000223"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose pyrophosphatase NudK"
                     /protein_id="HDV1985465.1"
                     /translation="MTQQITLIKDKILSDNYFTLHNITYDLTRKDGEVIRHKREVYDR
                     GNGATILLYNAKKKTVVLIRQFRVATWVNGNESGQLIETCAGLLDNDEPEVCIRKEAI
                     EETGYEVGEVRKLFELYMSPGGVTELIHFFIAEYSDNQRANAGGGVEDEDIEVLELPF
                     SQALEMIKTGEIRDGKTVLLLNYLQTSHLMD"
     gene            46840..47883
                     /locus_tag="RHX21_000224"
     CDS             46840..47883
                     /locus_tag="RHX21_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1176 domain-containing protein"
                     /protein_id="HDV1985466.1"
                     /translation="MRYRIFLLFFFALLPTSLVWAAPAQRAFSDWQVTCNNQNFCVAR
                     NTGDHNGLVMTLSRSAGAHTDAVLRIERGGLKSPDASEGEIAPRLLLDGEPLALSGDK
                     WRISPWLLVTDDTATITAFLQMIQEGKAITLRDGNQTISLSGLKAALLFIDAQQKRVG
                     SETAWIKKGDEPPLSVPPAPALKEVAVVNPTPTPLSLEERNVLLDYGNWRMNGLRCSL
                     DPLRREANVTALTDDKALMMISCEAGAYNTIDLAWIVSRKKPLASRPVRLRLPFNNGQ
                     ETNELELMNATFDEKSRELVTLAKGRGLSDCGIQARWRFDGQRFRLVRYAAEPTCDNW
                     HGPDAWPTLWITR"
     gene            complement(47979..49982)
                     /gene="tkt"
                     /locus_tag="RHX21_000225"
     CDS             complement(47979..49982)
                     /gene="tkt"
                     /locus_tag="RHX21_000225"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDV1985467.1"
                     /translation="MSRKDLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFL
                     KHNPTDPTWYDRDRFILSNGHASMLLYSLLHLTGYDLPLEELKNFRQLHSKTPGHPEI
                     GYTAGVETTTGPLGQGLANAVGLAIAERTLAAQFNQPDHEIVDHFTYVFMGDGCLMEG
                     ISHEVCSLAGTLGLGKLIGFYDHNGISIDGETEGWFTDDTAKRFEAYHWHVIHEIDGH
                     DPQAVKEAILEAQSVKDKPSLIICRTVIGFGSPNKAGKEEAHGAPLGEEEVALARQKL
                     GWHHPPFEIPKKIYHAWDAREKGEKAQQSWNEKFAAYKKAHPQLAEEFTRRMSGGLPK
                     DWEKTTQKYINELQANPAKIATRKASQNTLNAYGPMLPELLGGSADLAPSNLTIWKGS
                     VSLKEDPAGNYIHYGVREFGMTAIANGIAHHGGFVPYTATFLMFVEYARNAARMAALM
                     KARQIMVYTHDSIGLGEDGPTHQAVEQLASLRLTPNFSTWRPCDQVEAAVGWKLAVER
                     HNGPTALILSRQNLAQVERTPDQVKEIARGGYVLKDSGGKPDIILIATGSEMEITLQA
                     AEKLAGEGRNVRVVSLPSTDIFDAQDEEYRESVLPSNVAARVAVEAGIADYWYKYVGL
                     KGAIVGMTGYGESAPADKLFPFFGFTAENIVAKAHKVLGVKGA"
     gene            complement(50002..50952)
                     /gene="tal"
                     /locus_tag="RHX21_000226"
     CDS             complement(50002..50952)
                     /gene="tal"
                     /locus_tag="RHX21_000226"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HDV1985468.1"
                     /translation="MNELDGIKQFTTVVADSGDIESIRHYHPQDATTNPSLLLKAAGL
                     SQYEHLIDDAIAWGKKNGKTQEQQVVAACDKLAVNFGAEILKIVPGRVSTEVDARLSF
                     DKEKSIEKARHLVDLYQQQGVEKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSF
                     AQARACAEAGVFLISPFVGRIYDWYQARKPMDPYVVEEDPGVKSVRNIYDYYKQHHYE
                     TIVMGASFRRTEQILALTGCDRLTIAPNLLKELQEKVSPVVRKLIPPSQTFPRPAPMS
                     EAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL"
     gene            51241..53520
                     /gene="maeB"
                     /locus_tag="RHX21_000227"
     CDS             51241..53520
                     /gene="maeB"
                     /locus_tag="RHX21_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxaloacetate-decarboxylating
                     malate dehydrogenase"
                     /protein_id="HDV1985469.1"
                     /translation="MDDQLKQSALDFHEFPVPGKIQVSPTKPLATQRDLALAYSPGVA
                     APCLEIEKDPLKAYKYTARGNLVAVISNGTAVLGLGNIGALAGKPVMEGKGVLFKKFA
                     GIDVFDIEVDELDPDKFIEVVAALEPTFGGINLEDIKAPECFYIEQKLRERMNIPVFH
                     DDQHGTAIISTAAILNGLRVVEKNISDVRMVVSGAGAAAIACMNLLVALGLQKHNIVV
                     CDSKGVIYQGREPNMAETKAAYAVVDDGKRTLDDVIEGADIFLGCSGPKVLTQEMVKK
                     MARAPMILALANPEPEILPPLAKEVRPDAIICTGRSDYPNQVNNVLCFPFIFRGALDV
                     GATAINEEMKLAAVRAIAELAHAEQSEVVASAYGDQDLSFGPEYIIPKPFDPRLIVKI
                     APAVAKAAMESGVATRPIADFDVYIDKLTEFVYKTNLFMKPIFSQARKAPKRVVLPEG
                     EEARVLHATQELVTLGLAKPILIGRPNVIEMRIQKLGLQIKAGVDFEIVNNESDPRFK
                     EYWTEYFQIMKRRGVTQEQAQRALIGNPTVIGAIMVQRGEADAMICGTVGDYHEHFSV
                     VKNVFGYRDGVHTAGAMNALLLPSGNTFIADTYVNDEPDAEELAEITLMAAETVRRFG
                     IEPRVALLSHSNFGSSDCPSSSKMRQALELVRERAPELMIDGEMHGDAALVEAIRNDR
                     MPDSPLKGSANILVMPNMEAARISYNLLRVSSSEGVTVGPVLMGVAKPVHVLTPIASV
                     RRIVNMVALAVVEAQTQPL"
     gene            53813..54148
                     /gene="eutS"
                     /locus_tag="RHX21_000228"
     CDS             53813..54148
                     /gene="eutS"
                     /locus_tag="RHX21_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutS"
                     /protein_id="HDV1985470.1"
                     /translation="MDKERIIQEFVPGKQVTLAHLIAHPGEELAKKIGVPDADAIGIM
                     TLTPGETAMIAGDLALKAADVHIGFLDRFSGALVIYGSVGAVEEALSQTVSGLGRLLN
                     YTLCEMTKS"
     gene            54161..54640
                     /gene="eutP"
                     /locus_tag="RHX21_000229"
     CDS             54161..54640
                     /gene="eutP"
                     /locus_tag="RHX21_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization acetate kinase EutP"
                     /protein_id="HDV1985471.1"
                     /translation="MKRIAFVGTVGAGKTTLFNALQGNYTLARKTQAVEFNDKGDIDT
                     PGEYFSHPRWYHALITTLQDVDMLIYVHGANDPESRLPAGLLDIGVSKRQIAVISKTD
                     MPDADVAATRKLLLETGFEEPIFELNSHDPQSVQQLVDYLASLTKQEEAGEKTHHSE"
     gene            54615..55316
                     /gene="eutQ"
                     /locus_tag="RHX21_000230"
     CDS             54615..55316
                     /gene="eutQ"
                     /locus_tag="RHX21_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization acetate kinase EutQ"
                     /protein_id="HDV1985472.1"
                     /translation="MKKLITANDIREAHARGEQAMSVVLRASIITPEAREVADLLGFT
                     ITECDESSPVTASVPASVPADKTESQRIRETIIAQLPEGQFTESLVAQLMEKVMKEKQ
                     SLEQGAMQPSFKSVTGKGGIKVIDGSSVKFGRFDGAEPHCVGLTDLVTGDDGSSMAAG
                     FMQWDNAFFPWTLNYDEIDMVLEGELHVRHEGETMIAKAGDVMFIPKGSSIEFGTTSS
                     VKFLYVAWPANWQSL"
     gene            55313..56116
                     /gene="eutT"
                     /locus_tag="RHX21_000231"
     CDS             55313..56116
                     /gene="eutT"
                     /locus_tag="RHX21_000231"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization cob(I)yrinic acid
                     a,c-diamide adenosyltransferase EutT"
                     /protein_id="HDV1985473.1"
                     /translation="MKDFITEAWLRANHTLSEGAEIHLPADSRLTPSARELLESRHLR
                     IKFIDEQGRLFVDDEQQQPQPVHGLTSSDEHPQACCELCRQPVAKKPDTLTHLSAEKM
                     VAKSDPRLGFRAVLDSTIALAVWLQIELAEPWQPWLADIRSRLGNIMRADALGEPLGC
                     QAIVGLSDEDLHRLSHQPLRYLGHDHLVPEASHGRDAALLNLLRTKVRETETVAAQVF
                     ITRSFEVLRPDILQALNRLSSTVYVMMILSVTKPPLTVKQIQQRLGETQ"
     gene            56113..57129
                     /gene="pta"
                     /locus_tag="RHX21_000232"
     CDS             56113..57129
                     /gene="pta"
                     /locus_tag="RHX21_000232"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HDV1985474.1"
                     /translation="MIIERCRELALRAPARVVFPDALDQRVLKAAQYLHQQGLATPIL
                     VANPFELRQFALSHGVAMDGLQVIDPHGNLAMREEFAHRWLARAGEKTPPDALEKLTD
                     PLMFAAAMVSAGKADVCIAGNLSSTANVLRAGLRIIGLQPGCKTLSSIFLMLPQYSGP
                     ALGFADCSVVPQPTAAQLADIALASAETWRAITGEEPRVAMLSFSSNGSARHPCVANV
                     QQATEIVRERAPKLVVDGELQFDAAFVPEVAAQKAPASPLQGKANVMVFPSLEAGNIG
                     YKIAQRLGGYRAVGPLIQGLAAPMHDLSRGCSVQEIIELALVAAVPRQTEVNRESSLQ
                     TLVE"
     gene            57168..57461
                     /gene="eutM"
                     /locus_tag="RHX21_000233"
     CDS             57168..57461
                     /gene="eutM"
                     /locus_tag="RHX21_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HDV1985475.1"
                     /translation="MEALGMIETRGLVALIEASDAMVKAARVKLVGVKQIGGGLCTAM
                     VRGDVAACKAATDAGAAAAQRIGELVSVHVIPRPHGDLEEVFPIGLKGDSSNL"
     gene            57568..57855
                     /gene="eutN"
                     /locus_tag="RHX21_000234"
     CDS             57568..57855
                     /gene="eutN"
                     /locus_tag="RHX21_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutN"
                     /protein_id="HDV1985476.1"
                     /translation="MKLAVVTGQIVCTVRHHGLAHDKLLMVEMIDPQGNPDGQCAVAI
                     DNIGAGTGEWVLLVSGSSARQAHKSETSPVDLCVIGIVDEVVSGGQVIFHK"
     gene            57867..59270
                     /locus_tag="RHX21_000235"
     CDS             57867..59270
                     /locus_tag="RHX21_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase EutE"
                     /protein_id="HDV1985477.1"
                     /translation="MNQQDIEQVVKAVLLKMQSSDTPPAAVHEMGVFASLDDAVAAAK
                     IAQQGLKSVAMRQLAIAAIREAGEKHARDLAELAVSETGMGRVEDKFAKNVAQARGTP
                     GVECLSPQVLTGDNGLTLIENAPWGVVASVTPSTNPAATVINNAISLIAAGNSVIFAP
                     HPAAKKVSQRAITLLNQAIVAAGGPENLLVTVANPDIETAQRLFKFPGIGLLVVTGGE
                     AVVEAARKHTNKRLIAAGAGNPPVVVDETADLARAAQSIVKGASFDNNIICADEKVLI
                     VVDSVADELMRLMEGQHAVKLTAEQAQQLQPVLLKNIDERGKGTVSRDWVGRDAGKIA
                     AAIGLKVPQETRLLFVETTAEHPFAVTELMMPVLPVVRVANVADAIALAVKLEGGCHH
                     TAAMHSRNIENMNQMANAIDTSIFVKNGPCIAGLGLGGEGWTTMTITTPTGEGVTSAR
                     TFVRLRRCVLVDAFRIV"
     gene            59281..60117
                     /gene="eutJ"
                     /locus_tag="RHX21_000236"
     CDS             59281..60117
                     /gene="eutJ"
                     /locus_tag="RHX21_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutJ"
                     /protein_id="HDV1985478.1"
                     /translation="MAHDEQWLTPRLQTAATLCNQTPAATESPLWLGVDLGTCDVVSM
                     VVDREGQPVAVCLDWADVVRDGIVWDFFGAVTIVRRHLDTLEQQFGRRFSHAATSFPP
                     GTDPRISINVLESAGLEVSHVLDEPTAVADLLQLDNAGVVDIGGGTTGIAIVKKGKVT
                     YSADEATGGHHISLTLAGNRRISLEEAEQYKRGHGDEIWPAVKPVYEKMADIVARHIE
                     GQGITDLWLAGGSCMQPGVAELFRKQFPALQVHLPQHSLFMTPLAIASSGREKAEGLY
                     AK"
     gene            60107..61294
                     /gene="eutG"
                     /locus_tag="RHX21_000237"
     CDS             60107..61294
                     /gene="eutG"
                     /locus_tag="RHX21_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311342.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization ethanol dehydrogenase
                     EutG"
                     /protein_id="HDV1985479.1"
                     /translation="MQNELQTALFQAFDTLNLQRVKTFSVPPVTLCGPGSVSSCGQQA
                     QTRGLKHLFVMADSFLHQAGMTAGLTRSLAVKGIAMTLWPCPVGEPCITDVCAAVAQL
                     RESGCDGVIAFGGGSVLDAAKAVVLLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGT
                     GSETTNVTVIIDTVSGRKQVLAHASLMPDVAILDAALTEGVPSHVTAMTGIDALTHAI
                     EAYSALNATPFTDSLAIGAIAMIGKSLPKAVGYGHDLAARESMLLASCMAGMAFSSAG
                     LGLCHAMAHQPGAALHIPHGLANAMLLPTVMEFNRMVCRERFSQIGRALRTKKSDDRD
                     AINAVSELIAEVGIGKRLGDVGATSAHYGAWAQAAQEDICLRSNPRTASLEQIVGLYA
                     AAQ"
     gene            61411..62637
                     /gene="eutH"
                     /locus_tag="RHX21_000238"
     CDS             61411..62637
                     /gene="eutH"
                     /locus_tag="RHX21_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HDV1985480.1"
                     /translation="MGINEIIMYIMMFFMLIAAVDRILSQFGGSARFLGKFGKSIEGS
                     GGQFEEGFMAMGALGLAMVGMTALAPVLAHVLGPVIIPVYEMLGANPSMFAGTLLACD
                     MGGFFLAKELAGGDVAAWLYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLA
                     GIVTIPIGCIAGGLVAMYSGVQINGQPVEFTFALILMNMIPVIIVAILVALGLKFIPE
                     KMINGFQIFAKFLVALITLGLAAAVVKFLLGWELIPGLDPIFMAPGDKPGEVMRAIEV
                     IGSISCVLLGAYPMVLLLTRWFEKPLMSVGKVLNMNNIAAAGMVATLANNIPMFGMMK
                     QMDTRGKVINCAFAVSAAFALGDHLGFAAANMNAMIFPMIVGKLIGGVTAIGVAMMLV
                     PKDDATAAKTEAEAQS"
     gene            62634..64037
                     /gene="eutA"
                     /locus_tag="RHX21_000239"
     CDS             62634..64037
                     /gene="eutA"
                     /locus_tag="RHX21_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HDV1985481.1"
                     /translation="MNTRQLLSVGIDIGTTTTQVIFSHLELVNRAAVSQVPRYEFIKR
                     EISWQSPVFFTPVDKQGGLKEAELKSLILEQYQAAGIAPESVDSGAIIITGESAKTRN
                     ARPAVMALSQSLGDFVVASAGPHLESVIAGHGAGAQTLSEQRLCRVLNIDIGGGTANY
                     ALFDAGKISGTACLNVGGRLLETDSQGRVVYAHKPGQMIVDECFGAGTDVRSLTGAQL
                     VQVTRRMAELIVEVIDGTLSPLAQALMQTGLLPAGVTPEIITLSGGVGECYRHQPADP
                     FCFADIGPLLATALHDHPRLREMNVQFPAQTVRATVIGAGAHTLSLSGSTIWLEGVQL
                     PLRNLPVAIPIDETDLVGAWQQALIQLDLDPKTDAYVLALPASLPVRYAAVLTVINAL
                     VDFVARFPNPHPLLVVAGQDFGKALGMLLRPQLQQLPLAVIDEVIVRAGDYIDIGTPL
                     FGGSVVPVTVKSLAFPS"
     gene            64049..65410
                     /gene="eutB"
                     /locus_tag="RHX21_000240"
     CDS             64049..65410
                     /gene="eutB"
                     /locus_tag="RHX21_000240"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit alpha"
                     /protein_id="HDV1985482.1"
                     /translation="MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQER
                     VAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLS
                     DETSVDDIAFTRKGLTSEVVAAIAKICSNADLIYGAKKMPVIKKANTTIGIPGTFSAR
                     LQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNI
                     PTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFN
                     RIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEY
                     LYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIM
                     GMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPS
                     LFF"
     gene            65431..66318
                     /gene="eutC"
                     /locus_tag="RHX21_000241"
     CDS             65431..66318
                     /gene="eutC"
                     /locus_tag="RHX21_000241"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit beta"
                     /protein_id="HDV1985483.1"
                     /translation="MDQKQIEEIVRSVMASMGQAAPAPSEAKCTTTTCAAPVTSESCA
                     LDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRS
                     KDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPD
                     VQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILG
                     AKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVI
                     VDLAKRMLEQKASGINMTR"
     gene            66328..66987
                     /gene="eutL"
                     /locus_tag="RHX21_000242"
     CDS             66328..66987
                     /gene="eutL"
                     /locus_tag="RHX21_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HDV1985484.1"
                     /translation="MPALDLIRPSVTAMRVIASVNADFARELKLPPHIRSLGLISADS
                     DDVTYIAADEATKQAMVEVVYGRSLYAGAAHGPSPTAGEVLIMLGGPNPAEVRAGLDA
                     MVAHIENGAAFQWANDAQDTAFLAHVVSRTGSYLSSTAGITLGDPMAYLVAPPLEATY
                     GIDAALKSADVQLVTYVPPPSETNYSAAFLTGSQAACKAACNAFTDAVLEIARNPIQR
                     A"
     gene            67000..67500
                     /gene="eutK"
                     /locus_tag="RHX21_000243"
     CDS             67000..67500
                     /gene="eutK"
                     /locus_tag="RHX21_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311336.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutK"
                     /protein_id="HDV1985485.1"
                     /translation="MINALGLLEVDGMVAAIDAADAMLKAANVRLLSHEVLDPGRLTL
                     VVEGDLAACRAALDAGCAAAMRTGRVISRKEIGRPDDDTQWLVTGFNRQPKQPVKEPD
                     APVIVAESADELLALLTSVRQGMTAGEVAAHFGWPLEKARNALEQLFSAGTLRKRSSR
                     YRLKPH"
     gene            67546..68598
                     /gene="eutR"
                     /locus_tag="RHX21_000244"
     CDS             67546..68598
                     /gene="eutR"
                     /locus_tag="RHX21_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator EutR"
                     /protein_id="HDV1985486.1"
                     /translation="MKKTRTANLHHLYHEPLPENLKLTPKVEVDNVHQRQTTDVYEHA
                     LTITAWQQIYDQLHPGKFHGEFTEILLDDIQVFREYTGLALRQSCLVWPNSFWFGIPA
                     TRGEQGFIGSQCLGSAEIATRPGGTEFELSTPDDYTILGVVLSEDVITRQANFLHNPD
                     RVLHMLRSQSALEVKEQHKAALWGFVQQALATFCENPENLHQPAVRKVLGDNLLMAMG
                     AMLEEAQPMVTAESISHQSYRRLLSRAREYVLENMSEPVTVLDLCNQLHVSRRTLQNA
                     FHAILGIGPNAWLKRIRLNAVRRELISPWSQSTTVKDAAMQWGFWHLGQFATDYQQLF
                     AEKPSLTLHQRMREWG"
     gene            complement(68604..69503)
                     /gene="hemF"
                     /locus_tag="RHX21_000245"
     CDS             complement(68604..69503)
                     /gene="hemF"
                     /locus_tag="RHX21_000245"
                     /EC_number="1.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-dependent coproporphyrinogen oxidase"
                     /protein_id="HDV1985487.1"
                     /translation="MKPDAHQVKQFLLNLQDTICQQLTAVDGTEFVEDSWQREAGGGG
                     RSRVLRNGGVFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYV
                     PTSHANVRFFIAEKPGAEPVWWFGGGFDLTPFYGFEEDAIHWHRTARDLCLPFGEDVY
                     PRYKKWCDDYFYLKHRNEQRGIGGLFFDDLNTPDFNHCFAFMQAVGKGYTDAYLPIVE
                     RRKAMAYGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEY
                     DYQPKDGSPEAALSEFIKVRDWV"
     gene            complement(69507..70376)
                     /gene="amiA"
                     /locus_tag="RHX21_000246"
     CDS             complement(69507..70376)
                     /gene="amiA"
                     /locus_tag="RHX21_000246"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiA"
                     /protein_id="HDV1985488.1"
                     /translation="MSTFKPLKTLTSRRQVLKAGLAALTLSGMSQAIAKDEPLKTSNG
                     HSKPKAKKSGGKRVVVLDPGHGGIDTGAIGRNGSKEKHVVLAIAKNVRSILRNHGIDA
                     RLTRSGDTFIPLYDRVEIAHKHGADLFMSIHADGFTNPKAAGASVFALSNRGASSAMA
                     KYLSERENRADEVAGKKATDKDHLLQQVLFDLVQTDTIKNSLTLGSHILKKIKPVHKL
                     HSRNTEQAAFVVLKSPSVPSVLVETSFITNPEEERLLGTAAFRQKIATAIAEGVISYF
                     HWFDNQKAHSKKR"
     gene            70590..71015
                     /locus_tag="RHX21_000247"
     CDS             70590..71015
                     /locus_tag="RHX21_000247"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311332.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HDV1985489.1"
                     /translation="MEIRVFRQEDFEEVITLWERCDLLRPWNDPEMDIERKMNHDVSL
                     FLVAEVNGEVVGTVMGGYDGHRGSAYYLGVHPEFRGRGIANALLNRLEKKLIARGCPK
                     IQINVPEDNDMVLGMYERLGYEHADVLSLGKRLIEDEEY"
     gene            71002..71451
                     /locus_tag="RHX21_000248"
     CDS             71002..71451
                     /locus_tag="RHX21_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311331.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2919 domain-containing protein"
                     /protein_id="HDV1985490.1"
                     /translation="MKSTEFHPVHYDAHGRLRLPLLFWLVLLLQARTWVLFVIAGASR
                     EQGTALLNLFYPDHDNFWLGLIPGIPAVLAFLLSGRRATFPRTWRVLYFLLLLAQVVL
                     LCWQPWLWLNGESVSGIGLALVVADIVALIWLLTNRRLRACFNEEKE"
     gene            71658..72233
                     /locus_tag="RHX21_000249"
     CDS             71658..72233
                     /locus_tag="RHX21_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpoE-regulated lipoprotein"
                     /protein_id="HDV1985491.1"
                     /translation="MKSLRLLLCAMPLMLTGCSTMSSVNWSAANPWNWFGSSTKVSEQ
                     GVGELTASTPLQEQAIADALDGDYRLRSGMKTANGNVVRFFEVMKGDNVAMVINGDQG
                     TISRIDVLDSDIPADTGVKIGTPFSDLYSKAFGNCQKADGDDNRAVECKAEGSQHISY
                     QFSGEWSGPEGLMPSDDTLKNWKVSKIIWRR"
     gene            72329..73228
                     /gene="yfeX"
                     /locus_tag="RHX21_000250"
     CDS             72329..73228
                     /gene="yfeX"
                     /locus_tag="RHX21_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311329.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphyrinogen peroxidase"
                     /protein_id="HDV1985492.1"
                     /translation="MSQVQSGILPEHCRAAIWIEANVKGEVDALRAASKTFADKLATF
                     EAKFPDAHLGAVVAFGNNTWRALSGGVGAEELKDFPGYGKGLAPTTQFDVLIHILSLR
                     HDVNFSVAQMAMEAFGDCIEVKEEIHGFRWVEERDLSGFVDGTENPAGEETRREVAVI
                     KDGVDAGGSYVFVQRWEHNLKQLNRMSVHDQEMMIGRTKEANEEIDGDERPETSHLTR
                     VDLKEDGKGLKIVRQSLPYGTASGTHGLYFCAYCARLHNIEQQLLSMFGDTDGKRDAM
                     LRFTKPVTGGYYFAPSLDKLMAL"
     gene            complement(73286..74590)
                     /gene="pbp4b"
                     /locus_tag="RHX21_000251"
     CDS             complement(73286..74590)
                     /gene="pbp4b"
                     /locus_tag="RHX21_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin binding protein PBP4B"
                     /protein_id="HDV1985493.1"
                     /translation="MKRTMLYLSLLAVSCSVSAAKYPVLTESSPEKAGFNVERLNQMD
                     RWISQQVDAGYPGINLLIIKDNQIVYRKAWGAAKKYDGSVLMEQPVKATTGTLYDLAS
                     NTKMYATNFALQKLMSEGKLHPDDLIAKYIPGFADSPNDTIKGKNTLRISDLLHHSGG
                     FPADPQYPNKAVAGALYSQDKGQTLEMIKRTPLEYQPGSKHIYSDVDYMLLGFIVESV
                     TGQPLDRYVEESIYRPLGLTHTVFNPLLKGFKPQQIAATELNGNTRDGVIHFPNIRTS
                     TLWGQVHDEKAFYSMGGVSGHAGLFSNTGDIAVLMQTMLNGGGYGDVQLFSAETVKMF
                     TTSSKEDATFGLGWRVNGNATMTPTFGTLASPQTYGHTGWTGTVTVIDPVNHMAIVML
                     SNKPHSPVADPQKNPNMFESGQLPIATYGWVVDQVYAALKQK"
     gene            complement(74595..76019)
                     /gene="murP"
                     /locus_tag="RHX21_000252"
     CDS             complement(74595..76019)
                     /gene="murP"
                     /locus_tag="RHX21_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylmuramic acid transporter subunit
                     IIBC"
                     /protein_id="HDV1985494.1"
                     /translation="MAKEISSELLNTILTRVGGPGNIASCGNCMTRLRLGVHDSSLVD
                     PNIKTLEGVKGVILTSDQVQVVFGPGKAHRAAKAMSELLGEAPVQDAAEIAAQNKRQL
                     KAKQTSGVQQFLAKFATIFTPLIPGFIAAGLLLGIATLIATVMHVPADAQGTLPDALN
                     FMKVFSKGLFTFLVILVGYNAAQAFGGTGVNGAIIAALFLLGYNPAATTGYYAGFHDF
                     FGLPIDPRGNIIGVLIAAWACARIEGMVRRFMPDDLDMLLTSLITLLITATLAYLIIM
                     PLGGWLFEGMSWLFMHLNSNPLGCAVLAGLFLIAVVFGVHQGFIPVYLALMDSQGFNS
                     LFPILSMAGAGQVGAALALYWRAQPHSALRSQVRGAIIPGLLGVGEPLIYGVTLPRMK
                     PFITACLGGAAGGLFIGLIAWWGLPMGLNSAFGPSGLVALPLMTSAQGILPAMAVYAG
                     GILVAWVCGFIFTTLFGCRNVNLD"
     gene            complement(76023..76919)
                     /gene="murQ"
                     /locus_tag="RHX21_000253"
     CDS             complement(76023..76919)
                     /gene="murQ"
                     /locus_tag="RHX21_000253"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HDV1985495.1"
                     /translation="MQLEKMITEGSNAASAEIDRVSTLEMCRIINDEDKTVPLAVERV
                     LPDIAAAIDVIHAQVSGGGRLIYLGAGTSGRLGILDASECPPTYGVKPGLVVGLIAGG
                     EYAIQHAVEGAEDSREGGVNDLKNIGLTAQDVVVGIAASGRTPYVIAGLEYARQLGCR
                     TVGISCNPGSAVSTTAEFAITPIVGAEVVTGSSRMKAGTAQKLVLNMLSTGLMIKSGK
                     VFGNLMVDVVATNEKLHVRQVNIVKNATGCNAEQAEAALIACERNCKTAIVMVLKNLD
                     AAEAKKRLDQHGGFIRQVLDKE"
     gene            77083..77940
                     /gene="murR"
                     /locus_tag="RHX21_000254"
     CDS             77083..77940
                     /gene="murR"
                     /locus_tag="RHX21_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MurR"
                     /protein_id="HDV1985496.1"
                     /translation="MLYLTKIRNAESEFTENEQKIADFLRANVSELKSVSSRKMAKQL
                     GISQSSIVKFAQKLGAQGFTELRMALIGEYSASREKTNATALHLHSSITSDDSLEVIA
                     RKLNREKELALEQTCALFDYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKI
                     GYRVACEADTHVQATVSQALKKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSL
                     ADSPLRRLAHFTLDTVSGETEWRSSSMSTRTAQNSVTDLLFVGLVQLNDVESLKMIQR
                     SSELTQRLK"
     gene            78069..78860
                     /gene="ucpA"
                     /locus_tag="RHX21_000255"
     CDS             78069..78860
                     /gene="ucpA"
                     /locus_tag="RHX21_000255"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311324.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase UcpA"
                     /protein_id="HDV1985497.1"
                     /translation="MGKLTGKTALITGALQGIGEGIARTFARHGANLILLDISPEIEK
                     LADELCGRGHRCTAVVADVRDPASVAAAIKRAKEKEGRIDILVNNAGVCRLGSFLDMS
                     DDDRDFHIDINIKGVWNVTKAVLPEMIARKDGRIVMMSSVTGDMVADPGETAYALTKA
                     AIVGLTKSLAVEYAQSGIRVNAICPGYVRTPMAESIARQSNPEDPESVLTDMAKAIPL
                     RRLADPLEVGELAAFLASDESSYLTGTQNVIDGGSTLPETVSVGI"
     gene            79018..80034
                     /gene="cysP"
                     /locus_tag="RHX21_000256"
     CDS             79018..80034
                     /gene="cysP"
                     /locus_tag="RHX21_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate/sulfate ABC transporter
                     substrate-binding protein CysP"
                     /protein_id="HDV1985498.1"
                     /translation="MAVNLLKKNSLALVASLLLAGHVQATELLNSSYDVSRELFAALN
                     PPFEQQWAKDNGGDKLTIKQSHAGSSKQALAILQGLKADVVTYNQVTDVQILHDKGKL
                     IPADWQTRLPNNSSPFYSTMGFLVRKGNPKNIHDWNDLVRSDVKLIFPNPKTSGNARY
                     TYLAAWGAADKADGGDKAKTEQFMTQFLKNVEVFDTGGRGATTTFAERGMGDVLISFE
                     SEVNNIRKQYEAQGFEVVIPKTNILAEFPVAWVDKNVQANGTEKAAKAYLNWLYSPQA
                     QTIITDYYYRVNNPEVMDKLKDKFPQTELFRVEDKFGSWPEVMKTHFTSGGELDKLLA
                     AGRN"
     gene            80034..80867
                     /gene="cysT"
                     /locus_tag="RHX21_000257"
     CDS             80034..80867
                     /gene="cysT"
                     /locus_tag="RHX21_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter permease
                     CysT"
                     /protein_id="HDV1985499.1"
                     /translation="MFAVSSRRVLPGFTLSLGTSLLFVCLILLLPLSALVMQLAQMSW
                     AQYWEVITNPQVVAAYKVTLLSAFVASIFNGVFGLLMAWILTRYRFPGRTLLDALMDL
                     PFALPTAVAGLTLASLFSVNGFYGEWLAKFDIKVTYTWLGIAVAMAFTSIPFVVRTVQ
                     PVLEELGPEYEEAAETLGATRWQSFCKVVLPELSPALVAGVALSFTRSLGEFGAVIFI
                     AGNIAWKTEVTSLMIFVRLQEFDYPAASAIASVILAASLILLFSINTLQSRFGRRVVG
                     H"
     gene            80867..81742
                     /gene="cysW"
                     /locus_tag="RHX21_000258"
     CDS             80867..81742
                     /gene="cysW"
                     /locus_tag="RHX21_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026168.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter permease
                     CysW"
                     /protein_id="HDV1985500.1"
                     /translation="MAEVTQLKRYDARPINWGKWFLIGIGMLVSAFILLVPMIYIFVQ
                     AFSKGLMPVLQNLADPDMLHAIWLTVMIALIAVPVNLVFGILLAWLVTRFNFPGRQLL
                     LTLLDIPFAVSPVVAGLVYLLFYGSNGPLGGWLDEHNLQIMFSWPGMVLVTIFVTCPF
                     VVRELVPVMLSQGSQEDEAAILLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEF
                     GAVSVVSGSIRGETLSLPLQIELLEQDYNTVGSFTAAALLTLMAIITLFLKSMLQWRL
                     ENQEKRAQQEEHHEH"
     gene            81732..82829
                     /gene="cysA"
                     /locus_tag="RHX21_000259"
     CDS             81732..82829
                     /gene="cysA"
                     /locus_tag="RHX21_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter ATP-binding
                     protein CysA"
                     /protein_id="HDV1985501.1"
                     /translation="MSIEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTL
                     LRIIAGLEHQTSGHIRFHGTDVSRLHARDRKVGFVFQHYALFRHMTVFDNIAFGLTVL
                     PRRERPNAAAIKAKVTKLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLL
                     DEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEATEVADRVVVMSQGNIEQA
                     DAPDQVWREPATRFVLEFMGEVNRLQGTIRGGQFHVGAHRWPLGYTPAYQGPVDLFLR
                     PWEVDISRRTSLDSPLPVQVLEASPKGHYTQLVVQPLGWYNEPLTVVMHGDDAPQRGE
                     RLFVGLQHARLYNGDERIETRDEELALAQSA"
     gene            82948..83859
                     /gene="cysM"
                     /locus_tag="RHX21_000260"
     CDS             82948..83859
                     /gene="cysM"
                     /locus_tag="RHX21_000260"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase B"
                     /protein_id="HDV1985502.1"
                     /translation="MSTLEQTIGNTPLVKLQRMGPNNGSEVWLKLEGNNPAGSVKDRA
                     ALSMIVEAEKRGEIKPGDVLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAA
                     MRAYGAELILVTKEQGMEGARDLALEMANRGEGKLLDQFNNPDNPYAHYTTTGPEIWQ
                     QTGGRITHFVSSMGTTGTITGVSRFMREQSKPVTIVGLQPEEGSSIPGIRRWPTEYLP
                     GIFNASLVDEVLDIHQRDAENTMRELAVREGIFCGVSSGGAVAGALRVAKANPGAVVV
                     AIICDRGDRYLSTGVFGEEHFSQGAGI"
     gene            complement(83862..84230)
                     /locus_tag="RHX21_000261"
     CDS             complement(83862..84230)
                     /locus_tag="RHX21_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfeK family protein"
                     /protein_id="HDV1985503.1"
                     /translation="MKKIICLVITLLMTLPAYAKLTAHEEARINAMLEGLAQKKDLIF
                     VRNGDEHTCDEAVSHLRLKLGNTRNRIDTAEQFIDKVASSSSITGKPYIVKIPGKSDE
                     NAQPFLHALIAQTDKTVPAQ"
     gene            84335..85186
                     /gene="pdxK"
                     /locus_tag="RHX21_000262"
                     /gene_synonym="thiJ"
     CDS             84335..85186
                     /gene="pdxK"
                     /locus_tag="RHX21_000262"
                     /gene_synonym="thiJ"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine/pyridoxal/pyridoxamine kinase"
                     /protein_id="HDV1985504.1"
                     /translation="MSSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGL
                     NVFAVPTVLLSNTPHYDTFYGGAIPDEWFSGYLRALQERDALRQLRAVTTGYMGTASQ
                     IKILAEWLTALRKDHPDLLIMVDPVIGDIDSGIYVKPDLPEAYRQYLLPLAQGITPNI
                     FELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVITSASGNEENQEMQVVVVTADSVNV
                     ISHSRVKTDLKGTGDLFCAQLISGLLKGKALNDAVHRAGLRVLEVMRYTQQHESDELI
                     LPPLAEA"
     gene            complement(85229..85738)
                     /gene="crr"
                     /locus_tag="RHX21_000263"
     CDS             complement(85229..85738)
                     /gene="crr"
                     /locus_tag="RHX21_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015833547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDV1985505.1"
                     /translation="MGLFDKLKSLVSDDKKDTGTIEIIAPLSGEIVNIEDVPDVVFAE
                     KIVGDGIAIKPTGNKMVAPVDGTIGKIFETNHAFSIESDSGVELFVHFGIDTVELKGE
                     GFKRIAEEGQRVKVGDTVIEFDLPLLEEKAKSTLTPVVISNMDEIKELIKLSGSVTVG
                     ETPVIRIKK"
     gene            complement(85779..87506)
                     /gene="ptsI"
                     /locus_tag="RHX21_000264"
     CDS             complement(85779..87506)
                     /gene="ptsI"
                     /locus_tag="RHX21_000264"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate-protein phosphotransferase
                     PtsI"
                     /protein_id="HDV1985506.1"
                     /translation="MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFL
                     SGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADA
                     AAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVA
                     ADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYL
                     ILDAVNNQVYVNPTNEVIDKMRAVQEQVASEKAELAKLKDLPAITLDGHQVEVCANIG
                     TVRDVEGAERNGAEGVGLYRTEFLFMDRDALPTEEEQFAAYKAVAEACGSQAVIVRTM
                     DIGGDKELPYMNFPKEENPFLGWRAIRIAMDRKEILRDQLRAILRASAFGKLRIMFPM
                     IISVEEVRALRKEIEIYKQELRDEGKAFDESIEIGVMVETPAAATIARHLAKEVDFFS
                     IGTNDLTQYTLAVDRGNDMISHLYQPMSPSVLNLIKQVIDASHAEGKWTGMCGELAGD
                     ERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDELMTLVN
                     KFIEEKTIC"
     gene            complement(87551..87808)
                     /gene="ptsH"
                     /locus_tag="RHX21_000265"
     CDS             complement(87551..87808)
                     /gene="ptsH"
                     /locus_tag="RHX21_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein Hpr"
                     /protein_id="HDV1985507.1"
                     /translation="MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGKSASA
                     KSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKLMAELE"
     gene            complement(88192..89163)
                     /gene="cysK"
                     /locus_tag="RHX21_000266"
     CDS             complement(88192..89163)
                     /gene="cysK"
                     /locus_tag="RHX21_000266"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HDV1985508.1"
                     /translation="MSKIFEDNSLTIGHTPLVRLNRIGNGRILAKVESRNPSFSVKCR
                     IGANMIWDAEKRGVLKPGVELVEPTSGNTGIALAYVAAARGYKLTLTMPETMSIERRK
                     LLKALGANLVLTEGAKGMKGAIQKAEEIVASNPEKYLLLQQFSNPANPEIHEKTTGPE
                     IWEDTDGQVDVFIAGVGTGGTLTGVSRYIKGTKGKTDLISVAVEPTDSPVIAQALAGE
                     EIKPGPHKIQGIGAGFIPANLDLKLVDKVIGITNEEAISTARRLMEEEGILAGISSGA
                     AVAAALKLQEDESFTNKNIVVILPSSGERYLSTALFADLFTEKELQQ"
     gene            complement(89348..90109)
                     /gene="cysZ"
                     /locus_tag="RHX21_000267"
     CDS             complement(89348..90109)
                     /gene="cysZ"
                     /locus_tag="RHX21_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate transporter CysZ"
                     /protein_id="HDV1985509.1"
                     /translation="MVSSFTSAPRSGFYYFAQGWKLVSQPGIRRFVILPLLVNILLMG
                     GAFWWLFTQLDVWIPTLMSYVPDWLQWLSYLLWPLAVISVLLVFGYFFSTIANWIAAP
                     FNGLLAEQLEARLTGATPPDTGIFGIMKDVPRIMKREWQKFAWYLPRAIVLLILYFIP
                     GIGQTVAPVLWFLFSAWMLAIQYCDYPFDNHKVPFKEMRTALRTRKITNMQFGALTSL
                     FTMIPLLNLFIMPVAVCGATAMWVDCYRDKHAMWR"
     gene            90339..91337
                     /gene="zipA"
                     /locus_tag="RHX21_000268"
     CDS             90339..91337
                     /gene="zipA"
                     /locus_tag="RHX21_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZipA"
                     /protein_id="HDV1985510.1"
                     /translation="MMQDLRLILIIVGAIAIIALLVHGFWTSRKERSSMFRDRPLKRM
                     KSKRDDDSYDEDVEDDEGVGEVRVHRVNHAPANAQEHEAARPSPQHQYQPPYASAQPR
                     QPVQQPPEAQVPPQHAPRPAQPVQQPVQQPAYQPQPEQPLQQPVSPQVAPAPQPVHSA
                     PQPAQQAFQPAEPVAAPQPEPVAEPAPVMDKPKRKEAVIIMNVAAHHGSELNGELLLN
                     SIQQAGFIFGDMNIYHRHLSPDGSGPALFSLANMVKPGTFDPEMKDFTTPGVTIFMQV
                     PSYGDELQNFKLMLQSAQHIADEVGGVVLDDQRRMMTPQKLREYQDIIREVKDANA"
     gene            91408..93423
                     /gene="ligA"
                     /locus_tag="RHX21_000269"
     CDS             91408..93423
                     /gene="ligA"
                     /locus_tag="RHX21_000269"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HDV1985511.1"
                     /translation="MESIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRE
                     LETKHPELITPDSPTQRVGAAPLAAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRL
                     KSNEKVTWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLH
                     GENIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKR
                     PLTFFCYGVGVLEGGELPDTHLGRLLQFKKWGLPVSDRVTLCESAEEVLAFYHKVEED
                     RPTLGFDIDGVVIKVNSLEQQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRT
                     GAITPVARLEPVHVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVL
                     SERPEDTREVVFPTHCPVCGSDVERVEGEAVARCTGGLICGAQRKESLKHFVSRRAMD
                     VDGMGDKIIDQLVEKEYVHTPADLFKLTAGKLTGLERMGPKSAQNVVNALEKAKETTF
                     ARFLYALGIREVGEATAAGLAAYFGTLEALEAASIEELQKVPDVGIVVASHVHNFFAE
                     ESNRNVISELLAEGVHWPAPIVINAEEIDSPFAGKTVVLTGSLSQMSRDDAKARLVEL
                     GAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVIDEAEMLRLLGS"
     gene            93425..93643
                     /locus_tag="RHX21_000270"
     CDS             93425..93643
                     /locus_tag="RHX21_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3820 family protein"
                     /protein_id="HDV1985512.1"
                     /translation="MEKEQLIEIANTIMPFGKYKGRRLIDLPEEYLLWFARKDEFPAG
                     KLGELMQITLLIKTEGLTQLVQPLKRPL"
     gene            complement(93640..94638)
                     /locus_tag="RHX21_000271"
     CDS             complement(93640..94638)
                     /locus_tag="RHX21_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bile acid:sodium symporter"
                     /protein_id="HDV1985513.1"
                     /translation="MKLFRILDPFTLTLITVVLLASFFPARGDFVPFFENLTTAAIAL
                     LFFMHGAKLSREAIIAGGGHWRLHLWVMCSTFVLFPILGVLFAWWKPVNVDPMLYSGF
                     LYLCILPATVQSAIAFTSMAGGNVAAAVCSASASSLLGIFLSPLLVGLVMNVHGAGGS
                     LEQVGKIMLQLLLPFVLGHLSRPWIGDWVSRNKKWIAKTDQTSILLVVYTAFSEAVVN
                     GIWHKVGWGSLLFIVVVSCVLLAIVIVVNVFMARRLGFNKADEITIVFCGSKKSLANG
                     IPMANILFPTSVIGMMVLPLMIFHQIQLMVCAVLARRYKRQTEQLQAQQESSTDKA"
     gene            94728..95654
                     /locus_tag="RHX21_000272"
     CDS             94728..95654
                     /locus_tag="RHX21_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV1985514.1"
                     /translation="MNYSLKQLKVFVTVAQEKSFSRAGERIGLSQSAVSHSVKELENH
                     TGVRLLDRTTREVVLTDAGQQLALRLERLLDELNSTLRDTGRMGQQLSGKVRVAASQT
                     ISAHLIPQCIAESHRRYPDIQFVLHDRPQQWVMESIRQGDVDFGIVIDPGPVGDLQCE
                     AILSEPFFLLCHRDSALAVEDYVPWQALQGAKLVLQDYASGSRPLIDAALARNGIQAN
                     IVQEIGHPATLFPMVAAGIGISILPALALPLPEGSPLVVKRITPVVERQLMLVRRKNR
                     SLSTAAEALWDVVRDQGNALMAGREGDPLYQI"
     gene            complement(95645..95986)
                     /locus_tag="RHX21_000273"
     CDS             complement(95645..95986)
                     /locus_tag="RHX21_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FlxA-like family protein"
                     /protein_id="HDV1985515.1"
                     /translation="MATISSTSIPSIQTQSSNRASQGSDVASQIARISQQIIKLTQQI
                     KEIVDTSGSAEDKQKQAELIQQQITLLETQLAQLQRQQAEKAQEKEQRLSLNVSLLNP
                     VENTTHIDIYI"
BASE COUNT        22884 a        24718 c        26025 g        22441 t
ORIGIN      
        1 tcaattggaa ctttcatatg acacttagaa tcaatgctct ctatagtgat gaataatcat
       61 cattcgaagt caggtgggat gcctgtctga atacacctcc ttcaggatgt gggggattct
      121 gctgagcatc tatgaaactg aatgcaactt atataaaaat acgtgataaa tggtgggggc
      181 ttccgctgtt cctgccttct ttaatcttgc ccattttcgc ccacattaat actttcgcgc
      241 atatttcttc cggtgaggtt tttctctttt atctgccttt ggcactgatg atcagcatga
      301 tgatgttttt cagctgggcg gcattgccag ggatcacctt agggattttt gtccgcaaat
      361 atgcagagct gggtttttac gaaacgctct cattaacggc taattttatt atcattatca
      421 ttctctgttg gggcggttac agggtcttta ctccccggcg taacaacgtt tcacatggtg
      481 atacccgttt aatttcccag cgtatattct ggcagatagt gtttcctgca acgctgtttc
      541 tgatactttt ccagtttgct gcatttgtag gattgctggc gagcagagaa aatctggtcg
      601 gtgtcatgcc ttttaacctc gggactttaa tcaattatca ggccttactg gtgggtaatc
      661 tgatcggtgt cccgctgtgc tacttcatca ttcgggtagt gcgaaatcca ttttatttac
      721 gtagctatta ttcgcaatta aaacagcagg ttgatgccaa agtcaccaaa aaagagttcg
      781 cgctctggct actggcatta ggtgctttat tgttgctgtt atgcatgccg ttaaatgaaa
      841 aaagcacaat ttttagcacc aattatacct tgtcattatt gctgcccctg atgatgtggg
      901 gagcgatgcg ctatggttat aagctgattt cgctgctctg ggcggtcgtg ttgatgatca
      961 gcatccacag ctatcaaaat tacattccca tttatcctgg ctataccacg cagctgacca
     1021 taacctcctc cagttatctg gtattctctt ttattgtcaa ttatatggct gtactggcaa
     1081 ctcgtcagcg agcggtagtc agacgcattc agcggcttgc gtatgtggac ccggtggttc
     1141 atctgccaaa tgttcgcgcc ctgaatcgcg cgttgcgtga tgccccctgg tctgcgcttt
     1201 gttatttacg catccctggc atggaaatgc tggttaagaa ctatggcatc atgctgcgga
     1261 ttcaatacaa gcaaaaactt tctcactggc tgtcaccctt gctggaaccg ggtgaagatg
     1321 tttatcagct ttcgggtaac gatctcgcgc tgcggctgaa tacagaatcg caccaggagc
     1381 gcattaccgc actggatagc catctcaagc aatttcgttt cttttgggat ggcatgccga
     1441 tgcaaccgca gattggcgtc agttactgct atgtgcgctc gccagtgaat catatctacc
     1501 tgctgctggg agagctaaat acggtcgccg aactttccat cgtgaccaac gccccggaaa
     1561 atatgcagcg tcgcggggca atgtatttgc aacgcgaatt gaaagataaa gtcgcgatga
     1621 tgaatcgact acagcaggcg ctggaacaca accatttttt cctgatggcc cagccgatta
     1681 ccggtatgcg tggtgatgtt taccatgaaa ttcttctgcg catgaaaggt gagaatgatg
     1741 aactgatcgg ccccgatagc ttcttgccgg tcgcgcacga atttggttta tcgtcgagta
     1801 tcgacatgtg gatcattgag catacgctgc aatttatggc tgaaaacaga gcgaagatgc
     1861 ccgctcaccg ttttgctatt aatctgtctc caacctcggt atgtcaggct cgttttcctg
     1921 ttgaagtcag tcagttgctg gataaatatc agattgaagc gtggcaactt atttttgaag
     1981 tcaccgaaag taatgctctg accaatgtta agcaggcgca aatcaccttg cagcatcttc
     2041 aggaattagg ctgccagatt gcgattgatg atttcggcac cggctacgcc agctatgcgc
     2101 ggcttaaaaa tgtgaatgcc gatctgctta aaattgacgg cagttttatc cgcaatattg
     2161 tgtcaaatag tctggattat cagatagtgg catcgatttg ccacctggcg cgaatgaaga
     2221 aaatgcgggt agtggcagag tacgttgaaa acgaagagat ccgcgaggcg gtgctctctt
     2281 tggggatcga ttatatgcag ggttatctta ttggtaagcc gcaaccgtta attgatacgc
     2341 tgaatgaaat cgaacccatt cgcgaaagtg cctgaataat gcgggccgac atttctcgtc
     2401 ggcccgcaaa gcattaagcg gcgatttcag gtgtactttc ttcttcaatt ttcaaccgcc
     2461 agccagccac gccttcccag tattcttgct ccttttccag atcaagcagt accagcgcat
     2521 tctgactaaa ccagtcatgc gggaaacgca gtgtccagtg actgtcatca gtaatcagtg
     2581 tcaatgttgg cggtgtggtg gttgcctgac gttgattgtt tagtaatacg ccaaggcgca
     2641 atagctgtat cagtggcagg aactgtttct tcttaaacaa ggtaaagcgc ggcagatcgt
     2701 cgagcttaat cgctttacgg tgatagcgca ccagtgtcgc catcatcagc tgctgttcct
     2761 gattaaaacc cggcaagtca ctgttttgca gaatataagc ggagtggcga tgcaaaccgc
     2821 tgtggttgat attcaacccg acctcatgca gcatggcggc ccatcgcagt agcgcctcca
     2881 gttgcggatg cgccagcttc ggttgctgtt cccgccactg ttcgtacatt tgcatagtgg
     2941 tatccagcac tcgtcgggcc tgttcgctgt cgatgtgata ctggttggcg aggctgctgg
     3001 cggtacgact acgcacatcc tgatgacgga aacgtccttc catttcatac agtacgcctt
     3061 cacgtaaagc cccgtcagaa aggcgcagtt cacggatggc taaagcatca aacacaccgc
     3121 ataaaatcgc cagtccagga acgaagactg ttttccgctc ttcggaaaga cccggtaaac
     3181 tcagcgatgc gaaattacgg tgacgtaaaa cttcttttac cagtttttcc agacgttccg
     3241 gggtaattat cccgtctttc tcgcccattt ccattaatac ttcatgggcg gcttttatgg
     3301 taccggaagc gcccattgcc acgttccagc cctgaatacg gaattgccag gttaaagttt
     3361 ccagtttttg tgctgccgcc atgcgagcgc gctggaaatt ctctttattg atgaccccgc
     3421 cagggaaata aagctgggca aagctgacac aacccatccg gcggctttca acgagaatag
     3481 gttcgaaatt ttcaccaatc accagttccg tagatccgcc gccaatatca ataaccagtt
     3541 tgcgaccttt ttccggttgg gtatgttcca ctcccataaa aatcagacgg gcttcttcat
     3601 taccggaaat aatttcaatc gggtagggaa tgaccttttc cgcgcgtttc agaaagtcag
     3661 tggcgttcag cgcctgacgc agcgtatggg taccaactat acagacgctg gcaggagaaa
     3721 acccttgtag ccgttcggca aaaagcgaca gacagttcaa accgcgcgtc attgcctctt
     3781 cactcaacat attatctggc cccaggccgt ccgccagatg cacccgctgt ttcaggcggc
     3841 caataatctg catggcacca tctaccacac gggctatgac catgtgaaaa ctgtttgaac
     3901 caagatcgac cgcagcaaac tcctgcggac gaggggattt atcgtgtatt ggcatagggt
     3961 tattcaggtt gttcgagtga tttgatgtag tcataaatcg ccaactgcgc ccgtactttg
     4021 cggcgattgc cgcggggaac gtagcgatta ctgagttctt tatcgatata acgagctttg
     4081 accgtatcgc tgaacaatat gtcgatgatg tccagcaccc gctgcttcag gcgcggatcg
     4141 agcagcggcg tcgccacttc aatacgataa tcaatattgc gcgtcatcca gtcggcggaa
     4201 gaaaggtaga cctttttatc gccgccattt tcaaaaatat aaacccggtc atgttcaagg
     4261 taacggtcaa caatactgat ggcacgaatg ttgtcgctaa tgccttccag attggggatc
     4321 agcgaacaca ttccgcgaac cagcagatta accggtacgc cggagctgga ggccgcatac
     4381 agacgatcaa ccaggccttt atcgacaagg ttatttagct tcagggtgat accgctgggc
     4441 agcccttgct gcgcgttggc gatttcgcgg tctaccattt catataacag acggcgagag
     4501 ttttgcggtg acaccattaa ataatcaaat gtcaccgggc ggtatgggtt ttcaataaag
     4561 ttaaataccc gccgtacttc gttggtgata cgcgcatcgg cggtcagcaa tgaatagtca
     4621 gtataaagac gcgcggtttt ttcgttaaag ttcccggtcc cgatgtgtgc gtaacgcacc
     4681 acttcaccgt tttcttttcg tgaaatcagg aacagtttgg cgtgaatttt cagccccggc
     4741 gcagagaaga taacgtgcac gcctgcttcg gtcaggcgct tcgcccagtg aatgttagct
     4801 tcttcgtcga aacgcgcctg taactcaacc accacggtga ctttcttacc gttatgtgcg
     4861 gcgtggatca tcgagtcgat gatgcgtgaa tctttcgcca cgcggtaaat gttaatttta
     4921 atcgccagta cgctcgggtc gaacgaagcc tgacgcagca gttccagcac atgctcaaag
     4981 gtgtgataag gataatagag caacacatcg cgttcgcgaa tggcatcaaa accattgcgg
     5041 aactgggctt tatcaaacca aatatggcgt aaacgcggca gtggtttgtt caccagattg
     5101 gctttgccga cattggggaa attaataaag tctttaaaat tatgataacg accgccgggg
     5161 acgatggagt cgtagcggga aatagtcagt ttttcgcgta acacttcaac cagcgcattg
     5221 ggcatatcgc gctgataaac aaaacgcacc ggctcagcag ttaaacgctg cttgagactg
     5281 gaagacatca actccatcag gctggcttcc atctcatgca ctaaatcgta ttcggcatcg
     5341 cgggtcatct tcattgaata ggcattcagc gcgtcataat caaagaagcc tttgaaaata
     5401 tcatcaaggc agtaacgcag aatgttatcc agaagaatca tcggcttgcg tcgacgcggc
     5461 gcttctggcg gtaaattcac aaagcgcggc actttatctg atgggatctc cagcagcgcg
     5521 taacggatgg tatcgccacg gataatttcc accgccagat aggtgtaatc atctttcagg
     5581 aactgcacta agtcagtgtc aggattgatt aaaatcggcg taatgtgctg acgcagatac
     5641 tgcttaaaat aatgacgcag ccagttttgt tgattgacgg agagctggcg ttcattaatc
     5701 aggaagatct ggttacgcgc catctccagc agcagctcgt tgtagaggcc gtcgaattcc
     5761 tgatcggctt tcagcacccg ggactgaatt ttgcccagta aatggcggga atgagagttg
     5821 gagccttgtt cttcgctaat aatgatgcgt cgcttcagtt cagcgaagcg gactttatag
     5881 aactcatcaa ggttattgga atagatcccc aggaaacgca tcctttcaat cagcgggtta
     5941 gatttgtccg ccgcttcctg aagcacgcgt tcattgaacg ataaccaact gagctctttt
     6001 tcgatgtata gcttttcctg acccattacc acttttactc cgttttattc acgggacact
     6061 gcctggatat tatggcgagc aatattggca gatgtccaac tatgccagaa aagggggaaa
     6121 aaaactgctg gagcttgcga tttacaggtg aattgaaaaa cgccagcggc agagctggcg
     6181 ctttaactac ggggcattac tcgtcggcag cgtagccctg cggcggcaga cgttgaccat
     6241 ccagccacgc ggcgttttcg tgcattttca gacgaccatc ggcaaaccag ctaatcacca
     6301 gtggataaat agcgtgttcc tgggtttgca cgcgggcggt gatgtcatct tccgtatcac
     6361 cagcaaatac cgggactttc gcctgtaaaa taaccgggcc accgtccagt tcatcggtga
     6421 cgaaatgcac cgatgtaccg tgctcttcat caccattttc cagcgcctga cgatgggtgt
     6481 gtaatccggg atatttcggc agcagagaag ggtgaatgtt cagcaaacgc ccggcatagt
     6541 gggagacaaa cgccgggctg agaatgcgca taaaaccagc cagcacgacc acatcgggtg
     6601 cgtacatgtc gatttcatga atcaactccc ggtcataggc ctcacgactg tcaaacgcgc
     6661 tggcgatgag cgtatgcgtt gcaatacccg cctggcgggc gcgttcaagg ccgaacgcgt
     6721 cggccttatt gctgaaaact gcccgtacgg tgcctttaat tttgttggtt ttacaggcgt
     6781 caataattgc ctgtaaatta cttccgttgc cggaaataag caccacaata ttcattattc
     6841 gataaccacg cgttgttcgg aatcagaggc tttgatgata ccgattttcc acgcgttttc
     6901 accgttggca ttgagtaggg cgagggcttt gtccacttcc ggagcaggca gggcaataat
     6961 catcccgacg ccgcagttga aggtgcgata catttcatgg cgctcaacgt tacctgccgt
     7021 ttgcagccag ttgaacactt ccggccactg ccaggaagat tcatcaatca ctgcctgggt
     7081 attatctggc aatacgcgcg gaatgttttc ccagaagccg ccgccggtca ggtgcgcaat
     7141 ggcatgcaca tcgacctttt caatcaactc cagcactgac ttcacgtaaa tgcgggtcgg
     7201 tgccagcaga tgatcggcta atggcttacc atcaagttcg gtggtttgcg gatcacaacc
     7261 gctgacttca agaattttgc gcaccagcga atagccgttc gagtgcggac cgctggaacc
     7321 gagtgcaatc agcacatcgc cgtcgctgac tttagagccg tcgatgattt ctgatttttc
     7381 taccacgcca acgcagaaac ccgcgacatc gtaatcttca ccgtgataca tccccggcat
     7441 ttctgccgtt tcgccaccca ccagtgaaca gcccgattgc agacatcctt ccgcaatgcc
     7501 gctgatcacc gctgaagcgg tatcaacatc cagttttccg gttgcgtaat agtcgaggaa
     7561 aaacagcggt tctgcacctt gcaccaccag gtcattaacg cacatggcga ccagatcaat
     7621 accaatggtg tcgtgacgtt ttaagtccat tgccagacgc agcttggtac ctacgccgtc
     7681 agtgccggaa accagcacgg gttcacgata tttttgcggc aatgcacaca gcgcaccgaa
     7741 gccgcccaga ccgcccatca cttccggacg acgcgttttc ttcactacgc ctttgattct
     7801 tccaaccaga gcattacccg cgtcaatatc aacaccggca tctttgtagc taagagaggt
     7861 tttatcggtc actgcttggg tccccacgcg ttacttgcgg tagaaaaata aaattcggcg
     7921 caattctaac agggaaagca aacgtttgcg agactgcttt acacaacctt tttgcacgtc
     7981 ttttccccag acgcgcggcg aaagaagact tgtgccaggg caaaggttag ttttcggatg
     8041 gaataatctt ctttcataac catttgaata taaaataact ttatctcaaa ccgttatcat
     8101 tttgactaaa gtcaacgaaa agaatattgc cgccttgaag aaaggaggta taatccgtcg
     8161 attttttttg tggctgcccc tcaaaggaga aagagtatga agatcgtgga agtcaaacac
     8221 ccactcgtca aacacaagct gggactgatg cgtgagcaag atatcagcac caagcgcttt
     8281 cgcgaactcg cttccgaagt gggtagcctg ctgacttacg aagcgaccgc cgacctcgaa
     8341 acggaaaaag taactatcga aggctggaac ggcccggtag aaatcgacca gatcaaaggt
     8401 aagaaaatta ccgttgtgcc aattctgcgt gccggtctgg ggatgatgga cggtgtgctg
     8461 gaaaatgttc cgagcgcgcg catcagcgtt gtcggtatgt accgtaatga agaaacgctg
     8521 gagccggtac cgtacttcca gaaactggtt tctaacatcg atgagcgtat ggcgctgatc
     8581 gttgacccaa tgctggcaac tggtggttcc gttatcgcga ccatcgacct gctgaaaaaa
     8641 gcgggctgca gcagcatcaa agttctggtg ctggtagctg cgccagaagg tatcgctgcg
     8701 ctggaaaaag cgcacccgga cgtcgaactg tataccgcat cgattgacca gggactgaac
     8761 gagcacggat acattattcc gggcctcggc gatgccggtg acaaaatctt tggtacgaaa
     8821 taaagaataa aaataattaa agccgacttt aagagtcggc ttttttttga gtaaagcgcc
     8881 tataacacat aatacagagg ataatactat gacgcgccgt gctatcgggg tgagtgaaag
     8941 accgccactt ttacagacaa tcccgcttag tttgcaacat ttgttcgcca tgtttggtgc
     9001 aaccgtcctg gtgcccgtct tatttcatat taacccggcg actgtactgt tatttaacgg
     9061 tattggaacg ctgctgtatc tcttcatctg taaagggaaa attccggctt atcttggttc
     9121 cagctttgcc tttatttcac cggtattgtt actgttgccg ttagggtatg aagtcgcgct
     9181 gggcggcttt attatgtgcg gcgtgctgtt ctgcctggtt tcttttatcg tgaagaaagc
     9241 ggggaccggc tggctggacg tgctgtttcc acctgcggca atgggcgcaa tcgttgccgt
     9301 catcggtctg gagctggcgg gcgtagctgc cggtatggcg ggtttactcc cggctgaagg
     9361 gcaaacgcca gactccaaaa ccatcatcat ctctattacc accctggcgg tcacggtttt
     9421 aggttccgtg ctgtttcgtg gtttcctggc aattatcccg attttaattg gcgtgctggt
     9481 gggctacgcg ctctctttcg caatgggaat tgtcgatacc acgccgatta ttaatgctca
     9541 ctggtttgcg ctgccaaccc tctatacgcc gcgcttcgag tggtttgcca ttctgactat
     9601 tctgccagcg gcgttagtgg ttattgccga acacgtaggg cacctggtag taacggctaa
     9661 tatcgtcaaa aaagatctgc tgcgcgatcc aggtctgcac cgttcgatgt ttgctaacgg
     9721 cctgtcgacc gtgatctccg gcttctttgg ctctacgcca aataccactt acggagaaaa
     9781 cattggcgtg atggcgatca cccgtgttta cagtacctgg gttatcggtg gggcggcgat
     9841 tttcgctatc ctgctttcct gtgtcggtaa actggctgcc gctatccaga tgatcccatt
     9901 gccggtgatg ggcggcgttt cgctgctgct ttatggtgtc atcggtgctt ccggtattcg
     9961 tgttttgatc gaatcgaaag tggattacaa caaagcacag aacctgatcc tgacttccgt
    10021 gattttgatc atcggcgtca gtggcgcgaa ggtaaacatc ggcgcggcgg agttaaaagg
    10081 tatggcgctg gcgaccatcg tcggtatcgg cttaagtttg atcttcaaac tgattagtgt
    10141 gctgcgccct gaagaagtgg tgctggacgc agaagacgcg gatataacag acaaataatg
    10201 taccgaccgg gcagtgttgc tgcccggttc aaacatcatg ggattctgtg gtaaacttct
    10261 cgcgattttg tgaaatcctg gttgaggtat ctctgaacac accggcacag ctctctttgc
    10321 cactttatct tcctgacgac gaaacctttg caagtttctg gccgggggat aactcctctt
    10381 tactggctgc gctgcaaaac gtgctgcgtc aggaacatag cggttacatc tatctctggg
    10441 cacgcgaagg cgcggggcgc agccatctgc tgcacgcggc ttgcgcggaa ttgtcgcagc
    10501 gtggcgatgc ggtgggctat gtcccgctgg ataaacgcac ctggtttgtt ccggaagtgc
    10561 tcgacggtat ggagcatttg tcgctggtct gtatcgacaa cattgagtgt attgcaggcg
    10621 atgagttgtg ggagatggcg attttcgatc tctacaatcg aattctggaa tcgggcaaaa
    10681 cacgattgtt gatcaccggc gatcgtccac cgcggcagtt gaatctggga ttaccggatc
    10741 tcgcgtcgcg actcgactgg gggcagatct acaaattgca gccactttct gatgaagata
    10801 agttgcaggc gctacagtta cgcgcgcgtt tgcgtggttt tgaactgccg gaagatgtgg
    10861 ggcgtttctt gctgaagcgg ctcgacagag aaatgcgcac gctatttatg acgttggatc
    10921 agttggatcg tgcgtcgatt accgcgcaac gtaagctgac cattccgttt gtgaaagaaa
    10981 ttctgaagtt gtagataagg tgtttattgt cggatgcggc gcgaacgcct tatccgaact
    11041 acgcgaagtt aatccatagt attcgtaggc cggataagac gtggcaagcg tcgcatccgg
    11101 caatgtgctt caactagcga tggagcacat cttaacccac gatttccagt acctgctccg
    11161 gtggacgacc aatccgcgct ttgccattcg cgaccacaat cgggcgctcc attagcttcg
    11221 gattatccac cattgcctga atcagcgcct cttcgctaag cgaactgtca gccaggttca
    11281 gttctttata aagatcctct ttctggcgca tcaattcacg ggcgctattc atccccagca
    11341 ttttcagcaa atcgcgcagc gttgccgcat cggcgggtgt ctcaaggtag agcaccactt
    11401 ctggctccac gccgttttct ttcagcaggt tcagcgtttc ccggctcttt gaacagcgtg
    11461 ggttatggta gatttttacc tgtttggtca ttgttcttcc tttaatgcga attacatctt
    11521 ggtataaggc ttaaagcgtt cctgcagctg gcgcaactgg tcgatgcgcg catcgtaacg
    11581 cgcttgttgc aggctgccta atttcacctg cgaactggcg ctactcaaca gcgaaatggc
    11641 ctgatcgagt cgtccggcga gcgcataacc ttctgctcgc gcagccagct cctgatcacg
    11701 gttatttagc gcggcttccg cctgtgccag caaatcccag ccgttgctgt catctttatt
    11761 attaaaggtg tagcgattca gaatattggc cgcttcttgt ggttgaccac cttgcagata
    11821 agcgttcgcc aggttgagct gcaacaccgg attggtgcgt aaatcgcggg catttttcag
    11881 gcgattgatc gcctcattgg ctttgttttg cccaagatcg atatcggtag ccagatcgag
    11941 ataccatgcg ttgccaggtt ctgccgccag taacggttgc agcgttttac gcgcctcgtc
    12001 gtatttattg gcttccatcg cctgtaaagc acgaccatat tgtgctgctc gttgctgacg
    12061 aacgtttcct ttcgcccatt catccagcaa atcactggtg agctggttac gtccggaatt
    12121 atacatcccc agtgtgcgcg ctttcgccag atagaaatct tccgacgact gcaccaccat
    12181 cgggcgcatc tgattagcac ggttgcgggc atctgccaga cgactttccg gcaacgggtg
    12241 agtcaataaa atttccggcg ggcgcgagga gtaacgcgcc tgatcgagta atttttcgag
    12301 gaaggtaggc atcgcctgcg gatcgaatcc cgagcgttgc agcacctgaa taccaatgcg
    12361 gtccgcttcc tgttcatttt gctgggtgaa actgatcatc ccctgacgcg ttcccgccag
    12421 tgtaccggtc agcgccgcca tccccgcctg cggactggcc atcgccagta aaatagaacc
    12481 taacgcgccg acccaggtca gcggcgcgct gcgctgctga tcttccatcg ctcgcgccag
    12541 gtgacgttgg gtgacgtggg agatttcgtg cgccataact gaagccagtt gactttcgtt
    12601 atcggaataa cggaacaggg cagagtgcag caccacgttg ccgccaaaga aagcaaaggc
    12661 gttaatttcg tcgttgttga tcagaaagaa atgaaacggt gtcttaaccg aattggcatg
    12721 cgaaaccaga cgcatcccca gcgaattaat atattgcgtt aacagcgggt cattaattaa
    12781 cggcgcgctg ccgcgtagct ggcggacata atagtcgccc atctgcattt cctgaccaat
    12841 ggaaagcgtg cttcctgcgg aggttcccat atccggcaag gtgtctgcgc tgtcggcaaa
    12901 cgccggggct acctgaccaa tggtcatagc agcaatgagg gttgcaacca ggtttttttt
    12961 caactgcctg aacataacct ctatcctgta tttctgaaga tagtcatttg accgatactg
    13021 tgaaatatcg ttcccaccgc gccgcctttg agtgtaacgg cgaagattag cccactcaaa
    13081 tgacttttca gtttcctgaa tccgtcataa aaagcgaagt cttttttgtg acatttcgat
    13141 acaattgcgg atcgcaatcc cgctcttgag gttcagggaa ggtctttatg ctcgaaatgt
    13201 tgatgcaatg gtatcgccgc cgttttagcg acccggaagc gattgccttg ctggttattt
    13261 tagttgccgg atttggcatt atctttttct ttagtggcct gcttgctccg ttgctggtgg
    13321 ctattgtgct ggcctatttg ctggaatggc caaccgtgcg cctgcaatct attggctgct
    13381 cccgccgctg ggcgacgtcg attgtattgg tggtttttgt cggtatattg ctactgatgg
    13441 cgttcgtggt actgcctatc gcctggcaac agggcatcta cttaatccgc gatatgccgg
    13501 ggatgctcaa taagctttct gactttgccg ccacgttgcc gcgccgctat ccggcgttaa
    13561 tggatgcggg cattattgat gcaatggccg aaaatatgcg cagtcggatg ctgaccatgg
    13621 gcgattcggt ggtgaaaatt tccctcgcct cgctggtcgg tttgctgacc atagccgtct
    13681 atctggtgct ggtgccattg atggtcttct tcctgctgaa agacaaagag cagatgctga
    13741 acgccgttcg tcgggtgctg ccgcgcaacc gtggactggc aggacaggtg tggaaggaga
    13801 tgaatcaaca aatcaccaac tatatccgcg gcaaagtgct ggagatgatc gtggtgggga
    13861 tcgccacctg gctggggttc ttgctctttg ggctgaacta ttcgctgctg ctggcggtgc
    13921 tggtcggctt ctcggtactt attccgtaca ttggcgcatt tgtggtgacc attccggtgg
    13981 ttggcgtggc gctattccag tttggtgcag gcacggaatt ctggagctgc ttcgcggtgt
    14041 atctgattat tcaggcgctg gacggcaacc tgttagtacc ggtgttgttc tccgaagcgg
    14101 ttaacctgca tccgctggtg attattttat cggtggtgat cttcggtggt ttgtggggat
    14161 tctggggcgt attcttcgcc attccattgg cgacgctgat caaagccgtg atccacgcct
    14221 ggcccgatgg gcaaatagcg caagaataat cttcagcccg acgaactgtt tcgccgggct
    14281 gatttttcag gattcctgac gtaaataaat agcccgataa cacatactca ccagcactgc
    14341 accgccgata atattaccca gcatcaccgg gagcagattg gcggtaataa aatggctgac
    14401 cgtcagtgca ggaaaattgt ctgcgctact gtgcgccagt tgccgaaggg gcgtggggca
    14461 aaatggcgaa tggcaatggc gaacggaatc acaaacaaat tggcgataca gtgctcaaag
    14521 ccactggcga caaacagggt gatgggcaaa atcatagcga cgattttgtc gcataacgaa
    14581 cgcccgcaat aactcatcca cagcgccagg caaaccatca gattgcacat aatgccgagg
    14641 ctgacagatt cagtaaatgt atgatgcatt ttgccctcgg cgcagtgtaa aaccgcgact
    14701 ccccacatcg cgttttcact catcaccagc ccggaaaacc agattaacaa actgaaacag
    14761 gcaatacctg ccagattacc gcaggccacc agaagtgcgt taatcagcca agttcgccaa
    14821 ctaataacgc cccgactttt tgccattacc gtcattaccg acgaggtgaa caggttggtg
    14881 ccgcaaaccg ccagcaaaat aaagccaagt gtaaagcaaa ggccgcccac cagatgggtt
    14941 aatgcctgtg aagacggggc atcggcgata actgaaaggt aaaaagtaaa tccgatcgcc
    15001 ataaacacgc cagcggacat cgccattaaa aagaccgaca ctttactgcg ggcaatttta
    15061 tgggaggcaa tccgttcagc gattgccgct tttctggcgc tcaactgcaa gtcgaaagag
    15121 agtttgtttc tcatgcatac tcctgcaaaa gcagattaca acacctcgcg aaccgagatt
    15181 cccagacgct gcattcgtga cagcagcgtg gtgcgcttca tccctaatcg tgtcgccgcg
    15241 ccacggggcc cggcaacaat gccattggtt tctcgcaata cctgaacaat gcgctgacgt
    15301 tcttcttcgt cattctctgg cgtcgtcggg tgcagcaact gcgccattga actgcgaagc
    15361 gctgaatctt catttagcgt cggcagtaaa cggctttgtc ggacattaag atgtaaattc
    15421 agactgttac cgcgagtcag cagtaccgct cgctcaatca cgttttccag ctcgcgcacg
    15481 ttgcccggcc agtcccacga catcaactgg cgtagcgcct cggtcgggat ggcgtcaatt
    15541 gaacgattca tatggcgcgc cattttttgc gtgaaatgct ttgctaaaag agggatatct
    15601 tccggacggt cgcgcagcgg cggcaattcc agtgggaaga cattcaggcg ataaaagaga
    15661 tcgctgcgaa actggcgatc ttcaaccatt tgccacaaat cacggttggt ggcggcaatg
    15721 actctgacat ttaccgggat cgttctactc ccgccgagac gctcaatctc ccgttcctgc
    15781 aatacgcgca gcagtttagg ctgaagttct aacggcagat cgccaatttc atcgagaaac
    15841 aacgtgccgc catcggcaat ttcaaaacga ccacgatggg tattaatcgc accagtaaac
    15901 gcccctttgt catgaccgaa taactcactt tccagaagac tggcggggat ggcagcgcag
    15961 ttgattttga ccagcggctt gtcgcgtcgc gggctaagtt gatggatcgc tctggcgatc
    16021 acctctttgc cggttccggt ttcaccgcaa atcaacaccg tactgtcgct cttcgccaca
    16081 atatctacct gctggagtag gtcttccatt gcctggcttt gatagataat gtcaccgacg
    16141 cccagattcg aaaggagctg ctcgctaagc tggtggtttt cttgctgcaa actttcctgc
    16201 aaatcggtca tgctacgcta ggcatcggca ttgccaacgg caatagcgat gcgatcggct
    16261 atgtgttgta gtagctggca gttttcctca ctaaagagag tggaagaggt atgcgccagc
    16321 aacaatgcac ccggtgtatg gttgccaaag gtaagcggta taaggagcgc agattcgcag
    16381 ccgttagatg caagtaagag taataacggg tcgcgttgcc agagaaacag atcatctgca
    16441 cggtgcgtca aggtcggttg tcgggtttgt agcgtttgtg tcagcaatac actgtcgcca
    16501 ggcatattgc gtggcagaca cgcacaatgt gaggcagaaa gatcgctgca ccacaggctg
    16561 aacttctcgt tctttcgatg atcgcccagt accatactga ctgaagccag accgaaaaaa
    16621 tgatggatct cacgagcgac gtcagcgatc agatcgtcga gatcaagatg tgacagcact
    16681 gcattagtga tatccaccag tacccgatga tgatcgcgat ctttctccag caaacgcagc
    16741 gccacctgct gttcttcatc attgagccat gattgcagaa ccggggtgat aatgcgtgcc
    16801 agccagttaa acagtgtgca atcctgggga gtaaaacggc agccgtgggt gcgaataaag
    16861 cgtagctccg ccattccact actgccgaga aggacggcgt gacgcgaata atcgatcatc
    16921 tcgccctgat actctgctgt tgccgtcaca tcgctgccat catcatggta gcggtaatag
    16981 acgttgcttt tgagaacatg cagttcaata agttgtaccg ggctgaacgg cggcggcagc
    17041 gggatgaagg cgcgtaataa agacgcctta ccgtgtttct gtgctaaccg ctccgcgagc
    17101 attccgttta ccgcttcaat tgttattcct tgcggcgggg caaacatcgc ctcgtctgac
    17161 atagccatca acagtcctta ttaatgagaa atccttctca cgcaattttt ctggccatca
    17221 gatagatggc cggttcctgc acaatttcat ccaacagatg aatgaattga atgctacgcg
    17281 cctgccacac agacgttgcg tcatctgcca gtggcgcgaa tgcccgggtc aacagggcgg
    17341 tgtggctggc gtcaataaca atctcaccaa aagtcatcac ccccagcatc ttacgtcggg
    17401 cttgctcctc ttcgacctgg gcaagccaat cttcgtattc cgtcagtggg cagcggaagg
    17461 cgacattcag acaatcaatc acgccaacgt gatggccgat agccagcgag taatacatta
    17521 cctgagagct gtgttccggc atctcgtcgc tactggcgac aaactttttt cgcagcgtcc
    17581 agaaaacaat ttccccgcac tcttcagtca tgtaaccccc ggagtacgcg aaagagttgc
    17641 tgaacgatac tattgagacg tggatcgtcg gcatcgcgca accaggtgtt aacccgattt
    17701 cctgtaggat cgtcgcttaa atggcgcagg agccgatcgc aaatttctcg cccctgacga
    17761 tagcccgcca gccgccgcgc ttctcgctca atggcgatac gctgtgatgg cgggatctgc
    17821 ggccacaacg gttgcatagt caccccggtg ggatcgcgat aatccaccgc gtgaatcttc
    17881 tgttgcagca aaccgagcgc cacggcgaaa ccgtgaatgg tggcggccgg tgttggcggg
    17941 cagccgggga tccaaacatc aatggggaca atggtgtcgc tgccgcccca gacgctgtag
    18001 agatcgtgga aaatccgccg ccggcaccgc acgcgccgta ggaaacacag attttatgat
    18061 cgggggcaga ctcatacgcc cgaagtgcag gcatacgcat cgcccgggtg actgcgccag
    18121 taaataacaa aatatcggcg tgacgcggtg atgaaacaac cttaatgcca aaacgttctg
    18181 cgtcgaatac tggtgtaatg gcggcaaaaa tttcgatttc acaggcgttg cagccaccgc
    18241 aatcgacgcg ataaacgtag gctgagcgac ggatatcctg tagcaaatgc cgcttcatct
    18301 tttgcgtttg ctcgtccagc gtgatgggct ggctgacatg ttgtgtaagc actggactca
    18361 tagctgctcc ttagccacca gcggtacatc tgtatcgtcg ttgagcagcg tcgcgcgttg
    18421 tttgcactcc gggcagacgc tcgcttgcgc ccataacatt tcgcggtttt gtggcgcatt
    18481 ttgttgctgt gccaacaatt cagcagccag tgcgacggtt ttttgctggg caaacgggcg
    18541 ttcgcaacgg ctgcaacgtt gtagatggaa cgtcgcgcgg gtatagagat cggctttatt
    18601 ggtgacggtc agttcaaagt tattggtaag ctggatggct ctggtcgggc acacttcttc
    18661 acaacgtccg cagtaaatac aacgccccag atagagctgc caggtgcgcg aattttgctg
    18721 gtcgtcggtc tggatagtca gcgcatttgc cggacaagca caggcgcagg caccgcaggc
    18781 aatacattgg ctgggcatca ggtccggttt cccgcgaaag cctgggctga cctccagtgg
    18841 cgcgaaggga tatttcaccg tcgcggttcc ggcgcgcata atagttttca gtaacttcag
    18901 catcttctgt ccttacttca gcggcgaacg gttacgatca atgccgtagc gttcgatctc
    18961 tttatacggc acggtttttg actggcgctt gcgcacatct accagcgtca cacggtcggt
    19021 acaggagtag cagggatcaa ggctaccgat aatcagcggt gcgtcagaaa cggtattgcc
    19081 gcgcagcatg taacgcaaca ccggccagtt ggcgtaggtg gcggcacggc agcgccagcg
    19141 gaacaatttt tggttatcac cgagcatgct ccagtgcacg tcttcaccgc gtggcgcttc
    19201 aacaaagccc agcgcgaatg cgtgaggttt atagctaaag ccttcggtca gcagtggggt
    19261 atccggcatg ttgtcgaggg caaattccag cattgccagc gaatcaaacg tctctttgac
    19321 acggaccatc acgcgggaga aaacatcgcc gccggtaaag gtaaacagtg tttttggaat
    19381 attgccgtag tcggcgtagg ggtgatcaaa gcgcaaatca cgggcgattt gtcggtcgag
    19441 aatgccaatg ccctgagtgc gttgttccat attcggcgta gcaagcagca tctctaccag
    19501 ctccgacacg tcggcgcgca tctcgcgcac cagtttcagc gtttgcagac gttgctcttt
    19561 gagaatatcg cggcgaacac caccaatcag attcagaccg taggttttac gcgacccgat
    19621 cagcaattcc gccatcgtca tcgacttttc ccgcactcgg aaaaattgca taaagccggt
    19681 atcaaaacca acgaaatggc aggagaggcc aaggttaagc aaatgactgt gtagccgttc
    19741 gacttccagc agaatcgagc gaatagtatg tgctcgttgc ggcacctcaa tccccagtgc
    19801 attttcaacc gaattggtat aggccacact gtgggcaaaa ccgcaaatcc cacacacgcg
    19861 gtccgataag aaggtcactt cgttgtagcc catccgcgtt tctgccagtt tctccatgcc
    19921 gcgatggaca taaaacaggc ggtaatcagc atcgacaatt tgctcgccat ccacaaacaa
    19981 gcggaagtga cccggttcat cggaggtgat atgcagcggg ccgacaggga tcacccgcgc
    20041 atcgctgttg ccctcattga taaacgcata cgtttcggaa tctgtcgtcg gttcagggcg
    20101 cagtcgataa tccatcgcat ctttgcgcag cggatgcata tcttccggcc agtcatcggg
    20161 caacaccagg cgacgctgat ccggcaggcc aaccggaatc agcccgtaca tatcgcgaat
    20221 ttctcgctcg ccccagaccg cggcagggac gcgcggtgtg actgacggaa actcccgact
    20281 gtcggcatcg accagtgcct tcaccacgat ccagcatttt tcggcccctt ccattgaaag
    20341 ggcataataa accgcgtaat gaccgttaag tgtccgctcg tcgttgccaa acaggactgg
    20401 aagccagcca tcatgttgat aataaagata atgtacaacg tcaggcagca gattgatttt
    20461 caccgtaatg gtgacctgtt caggcgtttg tcgctcttca tccagcaccg cgccggggaa
    20521 ctgcgttttc agggcggcga gaatcgcttc gccacgattt gacgatgaat taacgttcac
    20581 tgtgtttctc cgaaacagat gcggtgcctg aaggcaaaaa atcatgccag gtgctacgtt
    20641 gtgcaggcag gtcgtgcgtc cctgagagga ctatagtgga agcgcccgcc aggatcctga
    20701 tgacaggttg tggaatatgc gttcccatcg ccagcatcat gaccagcaga atcaccattg
    20761 gcgaggtggt caaccagccg agatcacccc ggttaacggc ctgcggcggt ttcgccatta
    20821 acacccgcgc agccatccgt accaggcccg ccagcaccag cgttaacagc aataacagca
    20881 ggacgataat cagcaggtga ttacgtgcca gtcctgcggt aacggtcata aattcgctaa
    20941 gaaaaatgtt gaagggcggc atccctgcca gcgccagcgc accgccgcca aacagcacgg
    21001 cggtaaatgg catgattttg agcatcccac agacgacgtt gagatcgcgc gtgccgtact
    21061 tgagcagtac attgccggaa ccgcagaaca gcagcgtttt tgccagactg tggtttaagg
    21121 tgtgcagcag cgcggcaaaa attcccagcg gcccgccaat gcctagcgcc accgcgacca
    21181 gccccatgtt ctccacgctg gagtacgcca gcagacgctt aatgtcccgc tgtaccagaa
    21241 tgaaaaatgc cgccacggca accgacaaca tgccgaagat gagcaacaac cggttgggga
    21301 aatcgctgcc gatggcttgg caaataatga tgtaatagcg aatcagcacc aacagcgcgc
    21361 agttcagcaa tacggcggag agcagggcgc tgaccggact cggcgcttca ctgtgagcat
    21421 ccggcagcca ggcgtgcatg ggaaatagcc cggttttggt accaaagcca attagcacaa
    21481 acacaaaggc caacagcatt aatgttgggt caagcaagga cgattgctta agaacctcgc
    21541 tccagaatat cgccatttct gcctgcggca taacgctggc ggcgttggcg tataccagca
    21601 cggtaccgaa cagaccaaaa gcgacaccaa cagtacaaat aatgatgtac ttccatgctg
    21661 attccagcga tgaacgctga ccgtaaatgc ctaccagaaa cgccgagctt aaggtggtgg
    21721 cttcgatcgc cgcccacatc acaatcaggt tattgctggt aacaaccagc agcatggtga
    21781 acaaaaacag atggaagaaa ccgtagtaat cgcacagtgt aacgggtgaa agctcgccgt
    21841 gtgccacttc atgacgcatg tagccaatcg agtaaacacc ggtgagaaag ccaatcacac
    21901 caagaatggc gaggaacaaa ccgcccagac catcaatatg aagccacagt cccgcagcga
    21961 atatttctcc tgcatcagcg gcagtttgga ccacccagag tgccagaatc agcagcagtg
    22021 tgatccctaa gctatgtaat acagtcaccg tacaagtcgc agagagcccc cgtttccggc
    22081 aggcaaaaca gagcagcgaa aaaagcagcg gcgtgagcag gagtaaagcg aacatcacag
    22141 aataactcat ctcattatcc cttcagcgcg gtcaagttgt tcacgtccag cgtgccgtgg
    22201 gtacgccata tttttcttgc cagtaacacc atcacaatga cggcgaagat ggcgtcggta
    22261 gcgataccta tttccaccag ttccggtgct cgccaggcaa gaagcgccag caccagatgg
    22321 gagccgtttt ccatcaggca gtaaccaaaa atttgccgca ggatattgcg ctggctgaca
    22381 atgcacagca ggccaagcag aaaatgacct aacgctaccg ccagcgccgg tttcagcccg
    22441 gtagccatcg gtagcttcac gggctgaacg acaaatgcgc aaagcaggac aattaacgcc
    22501 gcgagcagtg ccatcattgc cggaccgaat aacgcttttt ccgggatgtt ctggggaata
    22561 tttcgtgcag cgtaagtcat gattaacggt accagcagca ctttggtgat aaaggcgctg
    22621 gcggaccaga tcagcagttg ctctgcggcg aacaggcacg agagagtggc gaaaatagac
    22681 accagcacca gcgactggca ggcgtaaaat ccgcatgaca ggcgatagct tttgacgcta
    22741 atcacaaaca gcgatgtcag catcatcagt cccgccagat tatttacgat catagaaccg
    22801 gtcattcatc atctccttac tgcaaccagg tcgcggcgat tacgctggaa atcagcgaca
    22861 tcacaatcag tacaatcaac accaggcgca ttgaccctgg cagcggtgcg gcatcggcga
    22921 cggcctcgct cggtttgcca ggcacaacgc gaccaaacca gcgaataaac caggcgaaac
    22981 tggcgaccga ttcaatcatc agcagaatca tggcgggcag caggatccag tactccactg
    23041 acaacgcaaa accggcagca aacagcggga atttactgaa gaagccgttg aacggcggca
    23101 caccggtaat cgccagcgct gccacgcaga aacccacgcc tggcaacggc agggtgtgca
    23161 atacgccacg cagacgcggc aacaagcgcg tgccgcagct gtaactcagc gcacctgcta
    23221 caaggaaaaa caggctttta gcgaacgcgt ggttgacgat gtaggcgatg ctgccctcca
    23281 gtgccagccg cccactttca ccttcgatgc ggcgtggaga taggcactga tcggtgttgg
    23341 cgcttccatt gcatccggta gccacgcttg catcggtagc tgggccgatt tcccccacgc
    23401 ggcaaacagg atgccgccat aaaccagata acgtgcgtcg ccatgtaact cgctcatcgc
    23461 gctaagcaca cacgttccgg tctgcaaaaa cagcgtggcg gcggcaagat acaaccccaa
    23521 cgaaccgata tgggtgataa gcaacgcttt tagtgctgaa cgctgcgctt tatcgctctg
    23581 gtaataattg atcaacgccc aggagcagcc gcccgtaatt tcaaaaaaca acaactgacc
    23641 gagcagcgtc gaggagagta ccagtcccgc catcgcgccg ataaacacca gcaaaaatgc
    23701 gtaataacga ttcgtgccgt tatgcgggtg ttcgcgattt ttatccgtca gataacccgt
    23761 ggagtagatc gtgaccagca aaccgagaaa caccaccaca aacagaatca gcgtactcac
    23821 gcgatcaatg accaggccaa acaatgccac atcccccacg ttgaccaacg tcaacgtgac
    23881 ggcaacttta tcggcctgat aaaacgcgga gatcagcgac aacatgcaca gcgtggtcag
    23941 cgcggcgaac aaaacccccc attcggcggc ccgacgttgt ggcgaaaacg aaacgaccag
    24001 tgcgccgata aaaggcagca ataacgtcgt cagagcaaga ttttccatat tccgtcagtg
    24061 ctccttacag accggttaac cagaagaccc atgcaagcgc agcaaggctg aagccaagcc
    24121 aggtcacatg gtgaatgagt aaaaaacgcc cgcgtgccag cgtgttttct gcgattgagg
    24181 ccagtacaaa aatcagcaaa accttgagca gcgtaacgac aagtgaagtc agcaggcagg
    24241 cgagagaaag ttcttgcgcg cgcccaaagg acagaaacag ggccacaaac agtgatgcca
    24301 tcacgacctg tttcagcccc agcccccatt tcgctagcgc cagcccggca ccggaatatt
    24361 cggtcagcgg gccttcctgt aattcctgtt ctgcttcagc aacatcaaag ggaatttttc
    24421 ccatctcaat gaagcaggca aaaccacagg ccagtaacgc cagtacggtg gttagcggcg
    24481 agttccagcc catcgccagc gtattgctga tcatctcgat atgcgtggaa cctgctatca
    24541 gcgccaatac cagcagtgag agaataagca ttggttcgac cagaatgccg agcgtcaact
    24601 cgcgactggc accgactccc gcaaacggac ttccggtatc cagcccggaa agagcaaaga
    24661 aaaaacgaaa cagggcaaga agatagataa gggtgatcag atcgccgccg cccgcaaaag
    24721 gggaaacggt aataaacagt ggtaaggcca tcgccagcac cagcatgctg ctgattaata
    24781 cccacggcat caggcggaac atcagacctg aagatgtcgg cgcaacttcc tggcgtttaa
    24841 acagtttgtg gatatcgcga taatcctgcc agatccccgg cccgcggcgg gagtgcatac
    24901 gcgcgcgtat ctgccgggaa atacccgtaa aaagtggggt tagcatcagc agaatcacgg
    24961 cctgtgctaa cgcaaaaata accagatatc cgtcgcaaag agtttgtctc atggtgattt
    25021 ccttagacgg caatagcgat tagcagcaca accagtgcgg cgaccacata caggcaatag
    25081 agacgaaagt cgccgctttg cagatgctgt atttctttgg ccagccgttg ggtggcgctc
    25141 acgatggggc ggatcacccg ctcatcccag aagggttctg tgctctgagc cctggcggtg
    25201 acgtgcgcaa aacctttatt tagcctcagc gtagggtcga gctgttgtcg tagacgaaat
    25261 aacgcagaga agaccacacg cagcggctgc atcacgccat tgcctgacgg ggccatcgca
    25321 ttttcccagc cgtagccgca tgcccaggca tctcctgtgc gacgaaacgc tgcgcggcgc
    25381 gaacgacacc acagccagta aaggccaggc agcaaaggca tcgccagtag taacagcaac
    25441 agtaatgagg gggtgacctg tgtatgaaac gtgccgggta caagtgctat tccgctggcg
    25501 acagtgacgg gaggggtatt ggtaaacgca tgggcaatat gcattatctt cggtgccagc
    25561 caactggcac taagcgcaat taatacgcag agtgccgcga gcagtagcat ggcgacgatc
    25621 atcgtatttg gcacttcctg tgcctcttca gcgtgtgtac tgcgcggcgc accacagaaa
    25681 gtaataccgt acatttttac gaagcacatt actgccagcc caccagtgac tgccagcatt
    25741 accatagcaa taggacccgc aagttgtagc gctacggctt ccacacgact tagtgagaac
    25801 agcgactgcc aggtgtacca ttcgctgata aaaccattca gcggaggaat ggctgatatc
    25861 gcgaggcaac caatcaggca tgctgcggct gtccacggca tccgtttcgc cagtgccccc
    25921 attttttcca tgtcgtgggt atgcaaacgc gaaataatcg cgcccgcgcc gagaaatagc
    25981 agccctttga acagcgcatg gttgagcaga tgaaacagtg cgccgagcag tccaaccacg
    26041 gtgagcagcg ggtcgtgcag tgacagaccg accatcgcca caccgactgc cagcaaaata
    26101 atgccgacgt tttcgacggt actccaggcc agcagccgtt tgatatcctg ttccgccagc
    26161 gcatacagca cgcccaggag cgcggagatt gcgccgatcg ccatcaccag aatgccccac
    26221 cacagcggca aacccgtttg cgccagcagg tccatcgcta ctttcaggat gccgaaaata
    26281 ccgattttga ccattacgcc agacatcaac gccgaagcgt gcgatggtgc ggcagggtga
    26341 gcgcgcggca accagctgtg caacggcatc atcccggctt tcgcgccaaa accgaaaaag
    26401 gccagcagga acaccgccga cgccagcccc ggagaaagtg aaagcgtgcg gaaactggca
    26461 aaatcgaggc tgccgctttc gcgccccatc agcaagaagg cgatcataat cagcaccgat
    26521 ccggcgtggg cgataaaaaa gtagagcatg ccagcgttga tcgacgtttt atcctgcctg
    26581 gcaatgacca gaaacctgga agacagcgac atcatttcaa acagcacgat gaaccaaaaa
    26641 gcgttgtcca tcaccagcag ggcaaccatc gatgcgatga aaagattcat aaagaagccc
    26701 atcgccgccg cgcctttgcc ctcgtattcg cgcatataag tcaatgaata gagcgaacaa
    26761 accaccacca gcaaggagat aaccagcacc ataaatgccg agaggctatc cattcgcagg
    26821 gttaaatcgg caaagtcaaa aggggtggca aaatgggcga ctaaagttac accagcatgt
    26881 aattgcgtaa ttccgctgat gatgccaatc acgccgccca ccagcgatgt gatgccggaa
    26941 agcttaatag ccagtctgtc cagaccgagt aaaaacagcg aagccagact ggcaaacaga
    27001 tagaggatca gcgaccaggt taataattgc agggcatcca ttagtgttgc tcctgagtga
    27061 gggaaagggg atcctccccg ccattggcaa accagcttgc ggcaaggcgc tgtttttctt
    27121 tcatctgacg ttgcaggcta tcgtcggtga tcagccgtaa cgcctgattc gggcaagcgc
    27181 gaacgcaggc cggaccttct ggcaagaaat cacacaggtc gcatttcacc gcgacggtct
    27241 ggacacccgg ttcccagcgc agcaacgcat gttggggcag cacgttttct tcgccgtctt
    27301 tgagtgagcc ttcagcctga aaaacatatt gcgcatgggc attcaccgga cggcttcctg
    27361 aagcgctgat tgcgccaaat gggcagacca cggcgcaaag cttgcagcca atacagaggc
    27421 tttcgttgag ttggatcgca tcatccctct gagagatggc attgaccggg cagacctgca
    27481 ggcaaggggc ttcctcacag tgatgacaca cgacaggggc agtgattgtt gacgtcttcg
    27541 ccagggccag gcgcgggtgt tgctgtaaac cttgcgtttt atgcacgtcc gaacaggcag
    27601 cgagacaggt attacatcct gtacaccaca gtggttcggc caccacaaag cggttcatgt
    27661 cggctccttg aaaatgatat gaaacattgc atttcatatt gcataaagga tgccattctt
    27721 attaactcaa tatattcaat aagttatgta ttgactggat tctgaacggt acaaaaatga
    27781 tggtcattaa cgttcagcaa aaaatggatt cgacacccgt gtcgcagggg aaagcgagaa
    27841 tgtgatcttg atcacgagaa gtgaggtatg ctggccgcaa gcgcagccag cacggaatgg
    27901 agcaaagtaa tcaggcgtgt tctttcagcc agttcagcac aacgtcgtgg tgattgctgg
    27961 ttttgaaatc gtcaaagaca tgttcgattt tgccatcagc gtcaatcagg aagctgatgc
    28021 gatgaatgcc atcgtaggtt ttgcccatga aggacttttc accccagacg ccgaattgtt
    28081 cgcacacctg gtggtcctca tcagacagga gcgtaaagtt aagcagctct ttttccgcaa
    28141 aacgggagag tttttcgggt ttatcggtgc tgatacccag cacatcaacg cccgcttttt
    28201 tcaactcatc catgttatcg cgtaagccgc aggcctgtac ggtacagccg ggggtcatgg
    28261 ctttcgggta gaaataaacc agaacacgct gtccctggaa gtcggtcaaa ttaacttgtt
    28321 ctccgtcttg atccggcaag ctaaatttcg gtgcgatatc accggctttc agtggattca
    28381 ttacttaact ccatcctgtt catcatgttg ggaataattg acgacgttaa tactgccttg
    28441 tgcattgagt tctgtacata gggctttgaa cgcttgctca atatttgctg cgtccgcaga
    28501 tgcggggctg tgggcggtta tctgaatatg caactgcgca gcccgttcat tttcagcagg
    28561 ttgcgtgcgc gacaccagct ccgcaatgtt catatgatgc gcgtcgaaaa gtgctgtgaa
    28621 gcgttcaatt aaatgcgggg agtctgccac atcgacctga acccagacag atgctggcat
    28681 tggcggacgc ggacgcgccg tcgtgcgctt catcacgatt aaaagatcca gttcggcacc
    28741 tttcaacggt aacgttgatt caatcagagt aatggcattc catgaaccgg aaagcagcat
    28801 aataaacgtg aactcttctc ccagcatcgc caggcgactg tcttcaatat tacagccgca
    28861 actactgaca tgacgggtga tggtgttcac aattccaggg cgatcggcac ccaacgcagt
    28921 gatcaccaga taatgttgcg atgacagtgt caaactggtt attcctttaa ggggtgagtt
    28981 gttcttaagg aaagcataaa aaaaacatgc atacaacaat cagaacggtt ctgtctgctt
    29041 gcttttaatg ccataccaaa cgtaccattg agacacttgt ttgcacagag gatggcccat
    29101 gttcacggga agtattgtcg cgattgttac tccgatggat gaaaaaggta atgtctgtcg
    29161 ggctagcttg aaaaaactga ttgattatca tgtcgccagc ggtacttcgg cgatcgtttc
    29221 tgttggcacc actggcgagt ccgctacctt aaatcatgac gaacatgctg atgtggtgat
    29281 gatgacgctg gagctggctg atgggcgcat tccggtaatt gccgggaccg gcgctaacgc
    29341 tactgcggaa gccattagcc tgacgcagcg cttcaatgac agtggtatcg tcggctgcct
    29401 gacggtaacc ccttactaca atcgtccgtc gcaagaaggt ttgtatcagc atttcaaagc
    29461 catcgctgag catactgacc tgccgcaaat tctgtataat gtgccgtccc gtactggctg
    29521 cgatctgctc ccggaaacgg tgggccgtct ggcgaaagta aaaaatatta tcggaatcaa
    29581 agaggcaaca gggaacttaa cgcgtgtaaa ccagatcaaa gagctggttt cagatgattt
    29641 tgttctgctg agcggcgatg atgcgagcgc gctggacttc atgcaattgg gcggtcatgg
    29701 ggttatttcc gttacggcta acgtcgcagc gcgtgatatg gcccagatgt gcaaactggc
    29761 agcagaaggg cattttgccg aggcacgcgt tattaatcag cgtctgatgc cattacacaa
    29821 caaactattt gtcgaaccca atccaatccc ggtgaaatgg gcatgtaagg aactgggtct
    29881 tgtggcgacc gatacgctgc gcctgccaat gacaccaatc accgacagtg gtcgtgagac
    29941 ggtcagagcg gcgcttaagc atgccggttt gctgtaaagt ttagggagat ttgatggctt
    30001 actctgttca aaagtcgcgc ctggcaaagg ttgcgggtgt ttcgcttgtt ttattactcg
    30061 ctgcctgtag ttctgactca cgctataagc gtcaggtcag tggtgatgaa gcctacctgg
    30121 aagcggcacc gcttgcggag cttcatgccc cggctggaat gattttgccg gtgacctccg
    30181 gtgattatgc aatcccggtg accaacggta gtggtgctgt cggtaaggcg ctggacattc
    30241 gtccaccagc ccagccgctg gcactggttt ctggcgcgcg tacccagttc acgggcgata
    30301 ccgcttcatt gctggtggaa aatggtcgtg gcaatactct gtggccgcag gtggttagtg
    30361 tgctgcaggc gaaaaactac accatcaccc aacgtgatga tgctggtcag acactgacca
    30421 ccgattgggt acaatggaac cgtctggacg aagacgagca gtatcgtggt cgttatcaaa
    30481 tctctgttaa gccgcagggt tatcagcagg cggttacggt taaactgctg aacctggaac
    30541 aggcgggcaa accggttgca gacgcggctt ccatgcagcg ttacagcacg gagatgatga
    30601 acgttatttc cgccggtctg gataaatctg ccactgacgc cgcgaacgct gcgcaaaatc
    30661 gtgcctccac cactatggac gtacaaagtg caactgatga caccggttta ccgatgctgg
    30721 tcgtacgcgg gccgttcaat gtggtttggc aacgtctgcc agcggcgctg gaaaaagtgg
    30781 gcatgaaagt gaccgacagc acccgttcgc agggtaacat ggccgtaact tataagccgc
    30841 tgtctgacag cgactggcag gaactgggcg cgagcgatcc aggcctggca tccggtgact
    30901 ataaactgca ggttggcgat ttagataacc gcagcagcct acagttcatc gatccgaaag
    30961 gtcatactct gactcagagt cagaacgacg cgctggtagc tgtcttccag gctgcgttta
    31021 gcaagtaaaa atacagggct ggaatcatcc ggcccttttt tctgatatga tacgcaaacg
    31081 tgtgcgtcgg caggaaaacg cgattttagc ggtaattcgc acgaaatttg tttgtcggac
    31141 gtagttcgga taaggcgttc acgccgcatc cgacaaaaca tccggcacac cagacagcaa
    31201 aagattttaa aacgttaatt cacacccagg agtgataaag atgcaaaagc aagctgagtt
    31261 gtatcgtggt aaagcgaaaa ccgtatacag cacggaaaac ccggacctgt tggtgctcga
    31321 attccgcaat gatacgtcag caggggatgg cgcgcgcatt gagcagtttg atcgcaaagg
    31381 tatggtgaac aacaagttca actacttcat catgagcaaa ctggctgaag cgggtatccc
    31441 gactcaaatg gagcgtctgc tctccgatac cgaatgtctg gtgaaaaagc tggatatggt
    31501 gccggttgag tgtgtcgtgc gtaaccgtgc tgctggctct ctggtgaaac gtcttggaat
    31561 cgaagaaggt attgagctga acccgccgct gttcgatctg ttcctgaaaa acgacgccat
    31621 gcacgatccg atggtcaacg aatcttactg cgaaaccttt ggctgggtga gcaaagagaa
    31681 cctggcgcgt atgaaagagc tgacctacaa agcgaacgac gtgctgaaaa aactgttcga
    31741 tgatgctggt ctgattctgg tcgacttcaa gctggagttt ggcctgtaca aaggtgaagt
    31801 ggtactgggc gatgagttct ccccggacgg cagccgcctg tgggacaaag aaacactgga
    31861 gaaaatggac aaagaccgtt tccgccagag cctcggtggc ctgatcgaag cctatgaagc
    31921 cgtcgcccgc cgcctgggtg tacagctgga ctgatttttc tggttgcttg tttctttagc
    31981 cggagggtac tccggctaaa tgtctttgat acccccgcta caatacttct cattatctcc
    32041 ctttgacagg aaagtcatac caggccaata tgtatataca taacgtatat cccaaaaagg
    32101 gggggctatg gaaactactg tatttttaag taatcgcagt caggccgtca gattaccgaa
    32161 agcggtcgct ctgccagaag acgttaagaa agtagaaatt attgcgattg gtcgtacaag
    32221 aatcatcact cccgccggtg agtcctggga cagttggttt gatggcgaaa atgtgagtgc
    32281 ggattttatg gatatccgtg atcaacccgc aatgcaggaa agggaatcat tttgatgctg
    32341 aaattcatgc tggataccaa tatctgtatt ttcactatta agaataaacc agtacatgtc
    32401 agagagcggt ttaacctgaa ttctggccgg atgtgtataa gttctgtaac attgatggag
    32461 cttatctatg gggcagaaaa aagtcagatg ccagaacgca atttggcggt tattgaaggt
    32521 ttcgtatctc gtttggtagt gcttgattat gatagtgctg ctgcgacgca taccgggcaa
    32581 atcagggccg agcttgcccg gcagggaagg cctgttggac cttttgacca gatgatagcg
    32641 ggacatgctc gcagtcgcgg tttgattgtg gttaccaaca atacccgaga gtttgagcga
    32701 gtggcgggaa tcagactaga agactggagc taacattctc ttttacttct aacattcgta
    32761 aattatataa cgtggcatga agccttaatt cctccgccat ttcatcccgc tttcctgtgg
    32821 taatcttcct ctgaaccacc tacgatcatt tctataatga atatattgtt gaggtatcta
    32881 tgcgttggca agggcgacgt gaaagtgaca atgttgaaga caggcgcaac agctccggtg
    32941 gtccgtctat gggcggtcct ggttttcgcc tgccaagcgg taaaggcggg ctgattttac
    33001 tgttagtcgt gctggttgca ggctactatg gtgttgattt aaccgggtta atgactggac
    33061 agccggtttc ccaacaacaa tcaacgcggt ccattagccc taatgaagac gaagctgcaa
    33121 aattcacctc ggtgattctg gcaaccacgg aagacacctg gggacaacag ttcgagaaga
    33181 tgggtaagac ctatcagcaa ccgaagctgg tcatgtaccg tggaatgacg cgcaccggct
    33241 gcggggctgg tcagtccatt atggggccgt tctattgccc ggcggatggc acagtttata
    33301 tcgatctctc cttctatgat gacatgaaag acaaacttgg cgcggatggc gattttgccc
    33361 aggggtacgt tatcgcccat gaagtcggtc atcatgtgca gaaactgtta ggcatcgagc
    33421 cgaaagttcg tcaactgcaa caaaacgcga cgcaggcgga agtgaaccgc ttatctgtgc
    33481 gtatggaact ccaggccgac tgttttgccg gtgtctgggg gcatagtatg cagcagcaag
    33541 gcgttctgga aaccggcgat ctggaagagg cgctgaacgc ggcgcaggcc atcggcgatg
    33601 accgtttaca acagcaaagt caggggcgag tagtaccaga tagtttcaca catggcactt
    33661 ctcagcaacg ctacagctgg tttaaacgtg gtttcgacag cggcgatccg gcacaatgca
    33721 atacttttgg taaaagcatt taacttccgg ggcagggatg gctgaactga ctgcgcttca
    33781 cacattaaca gcgcaaatga aacgtgaagg gatccgccgc ttgctggtgt tgagcgggga
    33841 agagggttgg tgttttgatc atgcgcttaa gttgcgtgat gccttacctg gcgactggct
    33901 gtggatttcg ccgcagccag atgctgaaaa ccactgttca ccctcggcgc tacaaacttt
    33961 acttgggcgc gagttccggc atgcggtatt cgacgcccgc cacggctttg atgccgctgc
    34021 ctttgcagca cttagcggaa cgttgaaagc gggaagctgg ctggttttgt tactccctgt
    34081 atgggaagag tgggaaaacc aacctgatgc cgactcgctg cgctggagtg attgccctga
    34141 ccctattgcg acgccgcatt ttgtccagca tctcaaacgc gtacttacgg cggataacga
    34201 cgctatcctc tggcggcaaa accagccgtt ctcgttggcg cattttactc cccgtactga
    34261 ctggcacccc gcgaccggcg caccacaacc agaacaacag caactcttac agcagctact
    34321 gaccatgcct ccgggcgtgg cagcggtaac ggctgcgcgt gggcgcggta agtcggcgtt
    34381 ggcagggcaa ctcatttctc gtattgcggg cagtgcgatt gtcaccgcgc ccgcaaaagc
    34441 ggcaacggat gtactggcac aatttgcggg cgagaagttt cgctttattg caccggatgc
    34501 cttgttagcc agcgatgagc aagccgactg gctggtggtc gacgaagccg cagccatacc
    34561 tgcgccgttg ttgcatcaac tggtatcgcg ttttcctcga acgttgttaa ccactacggt
    34621 gcagggctac gaaggcaccg gacgtggttt tttgctgaaa ttttgcgctc gctttccgca
    34681 tttacaccgt tttgaactgc aacagccgat ccgctgggca cagggatgcc cgctggaaaa
    34741 aatggttagt gaggcactgg tttttgacga tgaaaacttc acccatacac cacaaggcaa
    34801 tatcgtcatt tccgcatttg aacaaacgtt atggcgaagc gagccagaaa cgccgttaaa
    34861 ggtttatcag ttattgtctg gtgcgcacta ccggacttcg ccgctggatt tacgccggat
    34921 gatggatgca ccagggcaac attttttaca ggcggctggc gaaaacgaga ttgccggagc
    34981 gctgtggctg gtggatgagg ggggattatc tcaacaactc agtcaggcgg tatgggcagg
    35041 ttttcgtcgc ccgcggggta atctggtggc ccagtcgctg gcggcgcacg gtagcaatcc
    35101 actggcagcg acattgcgtg gacggcgggt cagccggata gcagttcatc cggcgcgtca
    35161 gcgggaaggc acagggcagc aacttattgc tggtgctttg caatatacgc gtgacctcga
    35221 ctatctttcg gtgagttttg gttacaccgg ggagttatgg cgtttctggc accgctgcgg
    35281 ttttgtgctg gtgcggatgg gtaatcatcg tgaagccagc agcggttgct atacggcgat
    35341 ggcgctgtta ccgatgagtg atgcgggtaa acagctggct gaacgtgagc attaccgttt
    35401 acgtcgcgat gcgcaagctc tcgcgcagtg gaatggcgaa acacttcctg ttgatccact
    35461 aaacgatatc gtgctttctg acgacgactg gcttgaactg gccggttttg cttttgctca
    35521 tcgtccgcta ttaacgtcgt taggttgctt attgcgtctg ctacaaacca gtgaactggc
    35581 attaccggcg ctgcgtgggc gtttacagaa aaatgccagt gatgcgcagt tatgtaccac
    35641 acttaaactt tcaggccgca agatgttact ggtccgtcag cgggaagagg ccgcgcaggc
    35701 gctgtgcgca cttaatgatg ttcgcactga gcgtctgcgc gatcgcataa cgcaatggca
    35761 attttttcac tgactccttc aattttctcc catggtcatt gtgagtcagc ggcgtaaaat
    35821 taatgacatc agttaaggag ttcgccatga aacatgacca ttttgttgtt caaagcccgg
    35881 ataaacctgc gcaacagttg ttactgcttt tccacggtgt cggggataac ccggtggcaa
    35941 tgggggaaat aggtagctgg tttgcaccgc tgtttcctga tgcgctggtg gtgagtgtcg
    36001 gtggcgcgga gccgagcggt aatccggcgg ggcgtcagtg gttttcggtg cagggtatta
    36061 cggaagataa tcgccaggcg cgtgtggatg cgatcatgcc gacgtttatt gaaacggtgc
    36121 gctactggca gaaacagagc ggagtagggg ctaacgccac ggcactcatc ggtttctctc
    36181 aaggcgcgat tatggtgctg gagagcatta aagccgaacc gggccttgct tcacgcgtca
    36241 ttgcttttaa cggacgctat gcgagcctgc cggaaactgc gtctacagcc acgacaattc
    36301 acctgattca tggcggtgaa gatccggtta tcgatctggc gcatgcggtt gcggcgcagg
    36361 aagcgttaat cagtgccggt ggtgacgtga cgctggatat cgtggaggat ttaggccatg
    36421 cgatcgacaa tcgcagtatg caatttgccc tggatcactt gcgttatacc attccgaaac
    36481 attatttcga cgaagcgcta agtggcggta agcctggcga tgatgatgtg attgaaatga
    36541 tgtaaaagac agattacctg gcctgataag acgcgtgagc gtcgcatcag gcatcgttca
    36601 ccattgccgg atgcggcgtt aacgccttat ccggcctacg gttgagcact cagcttactt
    36661 cttcggttga tcctttttcg gccagtcgtc gtcatcgtcc cacttatcgt tgaaatcacg
    36721 atgcggggga agctccggct tgttggcgag aaatttctta tggtcgacgc gcttgagatc
    36781 tttaatcacg ttcagcagga cgcctaccaa aaagacaatc accagaatcc accaatattt
    36841 agccagccag tccatgctta tttcctcttg cagaaccact catcaggcga cgagctgttc
    36901 catgatacgt tgatacatac gggcaagtag ctgcaggtcg gcagcgttca cacattcatt
    36961 aattttatga atagtggcat tgaccggccc gagttccacc acctgcgccc ccatgcgagc
    37021 aataaagcgc ccgtcggacg ttccgcctgt ggtcagtagc tgcggtttaa tttcattata
    37081 gtgctcaacc gcgttaacga ccgcatccac cagtttaccg cgcgcggtca aaaatggctg
    37141 cccggaaagc caccagtcca ccgtataacg cagttgatgt ttttcaagca gggcaagcac
    37201 ctgtgctttg atcatctcat cagtcagttc ggtgctgaag cggaagttaa actgcacaaa
    37261 cagttcaccc ggaataacat tgttactgcc cgttcccgcc tgaatattag caatctgcat
    37321 actggtcgcc gggaaaaatt cattgccctg atcccactca atagccacta attcattaag
    37381 gaaaggtgct gcgcgatgta ctggattgtc agccagatgc gggtaggcca catgcccctg
    37441 aacgccatga atggtaaggt tgcaggttaa cgatccgcga cgaccatttt tcaccacatc
    37501 accaaccact tcgatactcg acggttcgcc gaccaggcag taatcgagac gctcattacg
    37561 tgccatcaac gcttcgacga cttttaccgt accgttgtgg gcactggctt cttcatcaga
    37621 ggtgatcaga aatgccagtc gccccgtatg gttgggatgt tgtgcgacaa agcgttctgc
    37681 cgctaccacc atcgccgcca gcgagccttt catatctgcc gcaccgcgtc cgaataacat
    37741 gccatcacga atggtgggtt caaacggcgg attgatccaa cgatcggcgt cgccaggcgg
    37801 caccacgtcg gtatgcccgg caaaggccaa cgtttcacct tgcccacgcc atgcccaaaa
    37861 attctgcgta tcggcaaaat ccatgcgttc aacggtaaaa ccgatcgcct gcaaacgttc
    37921 aatcaacaaa gcctggcatc ctgcgtcatc aggactcagg gaagggcggc gaataagctg
    37981 ttgtgtcagc tcaataaccg ggcacgacat agactacacc tcatggaaaa attgctgata
    38041 actggaatca ctgaaaccca gcagcatagg cttaccaggc gcgcagagca atggacgttt
    38101 gataattgca ggcatttcag tcattaatgc cgccgcagag gccgcatcgg tgattttatt
    38161 gcgggtggtt tcgtccagtt tacgccaggt tgtaccacgg gtgttcagta acgcttccca
    38221 gcctaattcg ttgataaaac cgttcaataa ttcgctgtcc agcccatcga cgcggtaatc
    38281 atgaaaacga tagtcgatgt tattggcttc cagccaacgg cgagcctttt taatggtgtc
    38341 acaatttttg atgccgtaaa gtgtaaccat aatgaatcct ttttcgattt atgagaataa
    38401 atactcattt aagggtgaaa acattttgcc tgcaaatgat tatcaggaaa tataacatta
    38461 tcgaagtatt caaattaaca actattaaat aatattaaac atttttaacg taaacattaa
    38521 gaatattcat cttgttatct gtctgtattt taaccagaat taaatcagta ttagatgccg
    38581 tatgaatatc tcgaaatgtt gctgtgtatc acatacaaat tatcaccgca ggaccatagt
    38641 atttacataa ggtttgtccc ccggaggtag tcatcgcagc aatcgagtaa attagcttca
    38701 ccacggtata ttgtttccgt agaataccca taattataag agaggttgtt atgattgaac
    38761 gtgaactggg gaactggaaa gactttatcg aagttatgct tcgtaagtaa ttcccgagac
    38821 aaagtataaa cagcaagaac ccgctgagca ggttcttaat cggaaagttg aaaaaggcga
    38881 cacattggca tgtcgccttt tttattgctt attccgggcg cggcttcagc gggaagcggc
    38941 ggcgcaccag cacaaagaac agcggcacga agtaaatagc cagaatagta gctgaaatca
    39001 tcccgcccat tacgccagta cccaccgcat gctgaccacc ggaaccggca cccgtgctgg
    39061 ttgccattgg caatacgccg aagataaatg ccagcgaggt catcagaatc gggcgtaaac
    39121 gctgacggca ggcgtggagc gtcgcttcaa acaggtcgtg gcctttttgg ttcatctcgt
    39181 tagcaaactc gacgatcagg atggcgtttt tcgccgataa accaatgacc gttaacaggc
    39241 ccacctggaa gtaaacgtcg ttttccagcc cgcgcatcca ggttgccagc agcgcgccga
    39301 taacccccag cggcacgacc agcattaccg agaacggtac cgaccagctt tcatacaatg
    39361 ccgccagaca caggaatact accagcaagg aaatggcgta cagcgccgga gcctgcgcgc
    39421 cggaaagccg ctcctgatac gacatcgccg tccactccag accaaagccg tttggcaact
    39481 gcttcactaa cgattccata atatccatcg ccgtaccggt actgaccccc ggtgcggctt
    39541 ccccaacaat ctcaaccgca gaataaccgt tatagcgttc cagacgcggc gagcctgtct
    39601 cccagcgtga ggtcgcgaaa gcagagaagg gcaccatgcc gccatcttta tttcggacat
    39661 accagagatt aatgtcatct ggcagcatgc gatacggcgc agctgcctgc acatagactt
    39721 tcttcacgcg accgcgatcc ataaagtcat taacatagct cgaaccccag gcggtttgca
    39781 gtgtgtcgtt aatatcgtcg atatcaacgc ccagcgcctg agctttacgc tggtcgatat
    39841 caatctgcaa ctgcggactg tcgtcgaggc cgttatggcg cacacgggtt agctccgggt
    39901 tttccgccgc cagcgccagc aactggttac gtgctgccat cagcgcatcg tgacctgctc
    39961 cagcgtggtc ctgcaactcc atatcaaaac ccgcagaact accaagaccg ctaattgctg
    40021 gcgggctgct ggcgataacg cgagcttctt taatcttgtt aaacgccttt gttgcacgct
    40081 cgataatggc aaacgaggtg ccggtcttac tgtcgcgttc gctccagtct ttcaggcgga
    40141 taaacattcg cgccacgttt tgcccgttac ccccggggcc agaaccaaca gtggcaaaca
    40201 ccgacatgat gttgtctttt tcatgggtga agtaatattt ctcgatttgc tcaacgactt
    40261 tcagggtctg ttgttgggtt gaaccgctgg gcaattgtac cgaggtagta aacatgccac
    40321 ggtcttccag cggtaagaac gacgtcggca aacgcaggaa caggaacacc atgccgccaa
    40381 gcagcaggac ataaatcaca atccagcgca ggctacggtg gagaattttc gccacccctt
    40441 tttcgtagcg ttcggcgttg cggttaaaca tctggttaaa ccaggcaaaa aagccttttt
    40501 gcccgtgatg ctcacctttt ttcagtggct taagtagtgt ggcacacaga gccggagtga
    40561 ggatcatcgc taccagtact gacagcacca tcgccgcaac aatggtaata gagaactggc
    40621 gatagatggc accggtggtg ccgccgaaga aggccattgg tacaaatacc gccgaaagaa
    40681 ccatcgcaat cccgaccagt gccccctgga tctgccccat cgatttacgt gtggcttcgc
    40741 gaggagtgag tccttcctca ctcataatac gttcgacgtt ttccaccacc acgatggcgt
    40801 catccaccag cagaccgatc gccagcacca tcgcgaacat ggttaaggtg ttgacgctgt
    40861 aaccaaaggc gtaaagtacg gagaaggttc ccatcaacac caccggcacg gcgatagtgg
    40921 gtatcagcgt ggcgcggaag ttttgcagga acagatacat aacgaggaaa accagagcga
    40981 tagcttccag cagcgttttc accacgtctt caatggaggc tttaacaaac gaggtggttt
    41041 catacgccac cttgtattcc agtccgtgcg ggaagtactg cgccagctcg tcgagacgat
    41101 tgagtaccag ctccgctgtc gccatttcgt ttgcgccgga ggccagtttt acccccagcc
    41161 cggaggctgg cttaccattg aagcggctaa gataatcgta tttctccgcc cccatttcga
    41221 cggtggcgac atcgcccagc cttacctctg agccgtcttg attcacccgc aaggtgatat
    41281 cgcggaactg ttctggtgtt tgcagcagtg actgggcgtt aatggtggcg ttgagcgcct
    41341 gcttatcgac ggaaggtgta ccaccaagtt gcccaaccgc aatctgcgcg ttctgtgact
    41401 caatggcatc agtgacatct ttagccgtca tctggaaact gttgagtttc gccgggtcca
    41461 gccagatacg catggaatat tgcgaaccat aggcatcgat atccccgacg ccattcacgc
    41521 ggcttaacgg gtcctgaata ttactggcaa cataatcggc aatatcctgt ttatccatcg
    41581 aaccatcggt agagacgaaa gcaatggtca gaatattggt atcgccggtt ttacgcaccg
    41641 tcacgccctg attttgcacc gcctgcggta actttcgcat ggctgattgc agctggtttt
    41701 gtacttgctg cacggcttcg tccggatcgg tgcctgcttt aaaacttaaa gtgacagatg
    41761 cctgaccggt gccactgctc tgagatgaca tatacatgag attatcgagg ccggtcatat
    41821 tttgctcgat aacctgggtc acggtgtttt ccagcgtctg ggccgatgcg ccgggatagt
    41881 tagcggtcac tcgcacattc ggtggcgcga gatcggggta ttgttcaacg ggcaatgaga
    41941 aaatcgccag ggtacctgtc agacacaaca ggattgccag cacccaggca aaaatggggc
    42001 gatcaataaa gaaattcgcc attaaaagag gacctcgtgt ttctgcgtat cgttgtaggc
    42061 ttgacttgct tcactgtagc ggcaaggtac gagccaatcg tggagaaaaa aaggagttaa
    42121 tgtaaattat catgcccttt tatactgaac cttaagtgca agtattcttt ggtcagtagg
    42181 aggcattaca tcagctgact ttcctcaccc tccgcggagc gaaagctaat actcactaac
    42241 gtgccgccgc cggaaggttg tgaaaaagtc agcgtcccac ccagccgttc cgcgcgttcg
    42301 cgcatgatat tcagaccata atgaccttcg ggctctttcg gttcaccgat gccaatcccg
    42361 ttatcacgga tataaaccgt gtgattgccg tccggcgcgg tgacgcaact gacggcgatt
    42421 tcgctggcgt tggcgtgctt catcgcattc agcaccgctt cgcgaataat ttgcaacaaa
    42481 tgcacctgca tttgcgcatc cagcgccagg gttggcagac ggcagtcgag ggtcagtttg
    42541 gcgctggttt gattttgtaa cgtatccagc atttccctca acgcggaggg gagatccgcc
    42601 tgctgcagcg tcaggcggaa agtagtcaac agctcgcgta actgccgata agcatcattc
    42661 aacgcctggg aaaaatcggc catgatactt tgtgcggtgg cgttatcttc cggtatcgaa
    42721 cgcttcagta acgtcaactg gatacgtaag taagaaagta cctgagccag cgagtcgtgc
    42781 aattcgcggg cgatggttgc acgttcttcc atcaacaata actgctgaaa atgcttctgc
    42841 gcctgattaa agtacaaacc gcgtcccagc atcgacgaaa cgctgttaag cagcggttct
    42901 gatgatgaaa cgtgactatt ttgccagtgc agttcgccgt aaaccgtctc ttgcattgtc
    42961 accggtaaaa tctgcatcgg caattccggg tttggttgcc cttcgctaat ccgccagttt
    43021 tcaccgacat ttaactccag atattcagcc gcttcattgt cgcgaacaat ctgcaaaata
    43081 tggcggaaac aatgcacatc aatctggctg gtgttcagcg cctgggaaca ttgatacaac
    43141 acctccagac gacgcttggc ctcgtggaga tcgcgggtct tttcttctac tgacgcctcc
    43201 agcgaaaggt acaatttatg cagctcgctc gacatctggt taaaggtttt tgcaagcaga
    43261 ccaagctcat tcggcagact ggtatccagc ggcggcgagt cgaactgtcc gtgttcaata
    43321 cgctgactgg cggtaaccag ctgattcagc ggggcaacca cctgatggcg tatgcggcgc
    43381 aaagtaaaaa agaccagcgt gaaaataccg ataccgccag ccagggaaat cgccaccacc
    43441 agcagcattt tgcgttcagc gtagtgctgt aaagccagca cgaacaggtc tatctgatta
    43501 acataattat taatattggc ctgataccac ggcaaatcgc ccttgctgag ccgattattc
    43561 atctccagcc agttggcatt cagatgcgca tagcgagttt ttactgcttc tggcacatac
    43621 cagacgttga gattggttaa taccggtgaa tgcagtgcct gctgaaacaa ctggcgatgt
    43681 gcattgagtt gtggactgcc actttgcaag tcgtagccca ggcggtaact ctgcatacgc
    43741 agcgatccgg caatattgat agcctcagcg tcgcgcaaac tgctcgccag agttagcaga
    43801 gcgatacccg tggaaagaat cgacagcagc acaatgtaaa aaaaggcccg ggccagactg
    43861 gccgagacgg gtcgtttaac aatcacacgc gtcttctcca caaaaaatca ttaatgttcc
    43921 agttcgctga aacacaattt agtcagtgat gggattattt gatctgccac agtttatagc
    43981 gaaatagtta cttattctgg gcacatgaac attgccgatt cccctgtaag tcgggtaata
    44041 acaacactca tataaagaat aaggttttta caaccaaaaa agaaggtcgt tatgaatcgt
    44101 tttattatgg ccaacagtca gcaatgtctg ggttgtcatg cttgtgaaat cgcctgtgtc
    44161 atggctcaca atgatgagca acatgtcctg agccaacacc attttcatcc ccgaattacg
    44221 gttatcaaac atcaacagca acgtagtgca gtgacctgtc accattgtga agatgcgccc
    44281 tgcgcccgta gctgccctaa tggcgcaatc agccacgttg atgacagcat tcaggtcaat
    44341 cagcaaaagt gtattggctg taaatcctgc gtggtggcct gtccttttgg tacgatgcaa
    44401 atcgtcctga cacccgtcgc ggcaggaaaa gtaaaagcca cggcgcataa atgcgacctt
    44461 tgtgcggggc gcgaaaacgg tcctgcctgt gttgagaatt gcccggcgga cgcgctgcaa
    44521 ctggtcactg acgtcgcact ctccggcatg gcgaaatccc gccgcttgcg caccgcgcgt
    44581 caggaacatc aaccgtggca tgccagtacc gcggcgcaag aaatgccggt aatgagtaaa
    44641 gtcgaacaaa tgcaggcaac gcccgcgcgt ggcgagccgg ataaactggc gattgaagcg
    44701 cgcaaaaccg gttttgatga aatttatctg ccatttcgcg ccgaccaggc acaacgggaa
    44761 gcctcgcgct gccttaagtg cggcgagcac agcgtttgtg aatggacctg cccgctgcat
    44821 aaccatatac cgcagtggat tgaactggtg aaagccggaa acatcgacgc cgccgtcgag
    44881 ctttctcacc agaccaacac cctgccggaa attaccggac gcgtttgtcc gcaagaccgt
    44941 ttgtgtgaag gtgcctgtac tattcgcgat gagcacggcg cggtaactat cggcaacatt
    45001 gaacgctata tttcagatca ggcgttggcg aaaggttggc gtcctgactt aagtcatgtc
    45061 accaaagtgg acaagcgggt ggcgattatc ggggcaggtc cggcagggct ggcctgtgcg
    45121 gatgttctga cccgcaatgg cgtggcggtg acggtgtacg atcgccatcc agaaatcggt
    45181 ggcttgctca ctttcggcat tccttctttc aaactggata aatccctgct ggcacgccgt
    45241 cgggaaatct tcagcgcgat ggggattcac ttcgaactca attgtgaagt gggtaaagat
    45301 gtctctttgg attcgctttt ggaacaatac gacgcggtct tcgttggcgt aggcacttac
    45361 cgttccatga aagcgggttt acccaatgaa gatgcgccgg gcgtttatga cgcgctgccg
    45421 ttcctcattg ccaacactaa acaggtgatg gggctcgaag agctaccgga agagccgttt
    45481 atcaataccg ccggacttaa cgtcgtggta ctgggcggcg gcgacaccgc gatggactgt
    45541 gtgcgtactg cgctgcgcca cggcgcgagt aacgtcacct gcgcttatcg tcgtgatgaa
    45601 gctaacatgc caggctcgaa gaaagaggtg aggaacgccc gcgaagaggg ggccaacttc
    45661 gaatttaacg tccagccggt ggcgcttgag ctgaatgaac aaggtcacgt ctgcgggatt
    45721 cgtttcctgc gcacgcgtct tggcgagccg gatgcccagg ggcgtcggcg acctgtaccg
    45781 attgagggca gtgaatttgt catgccagcc gatgcggtga ttatggcgtt tggcttcaat
    45841 ccacacggga tgccgtggct ggagtcgcac ggtgtaacgg tagacaaatg gggccgcatc
    45901 atcgcggatg tggaaagcca gtaccgttac cagaccacca atccgaaaat cttcgccggt
    45961 ggcgacgccg tgcgtggtgc ggatctggtg gttaccgcaa tggcagaagg acgtcatgcg
    46021 gcacagggga ttattgactg gctgggggta aaatcagtca aatctcactg atagcctgcg
    46081 cagacaaacc cgacttcaca gcgtaatata attgttcatt tcgcgctgtg gagtcggtat
    46141 gacgcaacaa atcaccctca ttaaagacaa aattctctcc gataactatt tcaccctgca
    46201 caacattact tacgatctca cgcgcaaaga tggcgaagtt atccgccata aacgtgaagt
    46261 ttacgatcgc ggtaatggtg cgacgatcct cctgtacaac gcgaagaaaa agaccgtggt
    46321 tctgattcgt cagttccgtg tcgctacctg ggttaatggc aatgaaagcg ggcagctgat
    46381 tgaaacctgc gccgggctgc tggataacga cgaaccggaa gtgtgcattc gtaaagaagc
    46441 gattgaagag acgggctatg aagtgggcga agtgcgcaaa ttatttgaac tgtatatgtc
    46501 gcctggcggt gtgactgagc taatccactt ttttatcgcc gaatacagtg acaatcagcg
    46561 cgctaacgcc ggtggcggtg ttgaagatga agatattgaa gtgctcgagc tgccgttcag
    46621 ccaggcgctg gagatgatca aaaccggcga gatacgtgac ggtaagacgg tgttattgct
    46681 taactatttg caaacgtcac atttaatgga ctgaaaaata acaataatat ttcgttgttt
    46741 attattggct caatccgaca aatctgattg agccgcgcta cctgcgcaac gaagatacga
    46801 cttgtgctgt ttgtttgaac ttctggggtc gtaccgtcca tgcgctatcg cattttcctt
    46861 ctcttttttt tcgctttgtt gccgacgtct ttggtgtggg cggcaccagc gcaacgggcg
    46921 ttttccgact ggcaggtcac ctgtaataac caaaacttct gcgtggcgcg caatacgggc
    46981 gatcataatg gactggtgat gaccctgagc cgcagcgccg gggcgcatac cgatgccgtt
    47041 ttacgtattg agcgcggcgg gttgaagtcg ccggatgcgt ctgaaggaga gatagcgcca
    47101 cggctgctgt tagatggtga gccgttggcg ttaagtggtg acaagtggcg gatttcacca
    47161 tggttattag taaccgatga tacggcaacc atcaccgcgt ttttgcagat gattcaggaa
    47221 gggaaggcga tcaccttacg cgacggcaat cagaccattt ctctgagtgg cttaaaagcg
    47281 gcgttgttgt ttattgatgc tcagcaaaag cgcgttggca gtgaaaccgc gtggatcaag
    47341 aaaggggacg aaccgccgct cagcgtaccg cccgcgcctg cgctgaaaga ggtcgcggtg
    47401 gttaacccaa cgccgacgcc actctcactc gaagaacgca acgttttgct ggattatgga
    47461 aactggcgga tgaatggtct gcgctgctcg cttgatccgt tacgtcgtga ggcgaatgtc
    47521 actgcgctga ctgatgataa agcgctgatg atgattagct gtgaggcagg ggcctataac
    47581 accattgatt tggcatggat tgtgtcgcgt aaaaagccac tagcctcgcg cccggttcgg
    47641 ttgcgtttgc cgttcaacaa cggtcaggag acgaatgaac tggaactgat gaacgcaaca
    47701 tttgatgaga aatcgcgtga actggtgacc ttagcgaaag ggcgcggatt aagcgattgt
    47761 ggcattcagg cgcgctggcg ctttgacggt cagcgttttc gcctggtgcg ttatgccgca
    47821 gaacccacct gcgataactg gcatgggcca gacgcctggc ccacgttgtg gatcacccgt
    47881 taaacaaaat tgcggggaca tgtaggccgg ataagacgct gtaggccgga taagacgcgt
    47941 cagcgtcgca tccggcaatc agcatccggc gatcaccatc aggcaccttt cactcccagc
    48001 accttatgcg cttttgccac aatattctcg gcggtaaagc caaagaacgg gaacagctta
    48061 tccgccggag cagattcccc gtaacccgtc atcccgacaa ttgccccttt cagaccaaca
    48121 tacttgtacc agtaatcggc aatacctgct tccaccgcca cgcgagccgc aacgttagaa
    48181 ggcaacaccg actcccgata ttcctcatcc tgggcgtcga aaatatcggt cgagggcagg
    48241 gaaactacgc gtacattgcg accttctcct gctaatttct ctgccgcttg cagggtaatt
    48301 tccatctctg aaccggtggc aatcaaaata atatctggct taccgccgct gtctttcagc
    48361 acataaccgc cacgagcaat ctctttaacc tgatccggcg tacgttccac ctgggccaga
    48421 ttctgccttg agaggatcag tgccgtcggt ccgttgtggc gctcaaccgc cagcttccag
    48481 cccaccgccg cttccacctg atcgcacggt cgccaggtgc tgaaatttgg cgttaagcgc
    48541 aggctggcca gttgctcaac agcctggtgc gtcggaccat cttcgcccag gccaattgag
    48601 tcgtgggtat aaaccataat ctgccgcgct ttcatcagtg ccgccatccg cgcggcgtta
    48661 cgggcgtatt caacaaacat caggaacgtc gcggtatacg gcacaaagcc gccgtggtgc
    48721 gcgatgccgt tggcgatagc ggtcatgcca aattcacgca ccccgtagtg aatgtagttg
    48781 cccgctggat cttccttcag cgaaacagaa cctttccaga tggtcaggtt gctgggagcc
    48841 agatccgccg aaccgccgag caactcaggc agcatcggcc cgtaagcgtt aagcgtattt
    48901 tgcgaagcct tacgggtagc gattttcgcc ggatttgcct gtaactcatt gatatatttc
    48961 tgagtcgttt tctcccagtc cttcggtaaa ccaccgctca tccgtcgggt aaactcttct
    49021 gccagttgcg gatgagcctt tttataggcg gcaaacttct cattccagct ctgctgcgct
    49081 ttttcgcctt tttcacgggc atcccaggcg tgataaatct ttttagggat ctcaaatggc
    49141 ggatggtgcc agcccagttt ttgccgtgcc agcgccactt cttcttcccc cagtggtgcg
    49201 ccgtgcgcct cttccttacc tgctttattc ggcgaaccaa agccaatcac cgtacggcag
    49261 ataatcagcg acggcttatc tttcacgctt tgcgcttcaa ggatcgcttc cttcaccgcc
    49321 tgcggatcgt gaccgtcgat ttcatggatc acatgccagt gataggcttc aaaacgtttt
    49381 gccgtatcgt cggtaaacca gccttctgtt tcaccgtcga tggaaatacc gttgtgatcg
    49441 taaaaaccaa tcagcttgcc cagtcccagc gtgcctgcca gcgaacagac ttcgtgggaa
    49501 ataccttcca tcaggcagcc gtcgcccata aacacatagg tgaagtgatc gacgatctca
    49561 tggtctggct ggttaaactg cgccgccaat gtacgttccg ctatcgccag cccgacggcg
    49621 ttcgccaaac cttgtccaag cgggccggtg gtggtttcaa cgcctgccgt atagccaatc
    49681 tccgggtggc ctggggtttt cgaatgcaac tgacggaagt tcttcagttc ttccagcggc
    49741 aggtcgtaac cggtcagatg tagcaaactg tagagcagca tcgacgcgtg accgttggaa
    49801 agaataaagc ggtcgcgatc ataccaggtt gggtcggtag ggttatgttt aagaaaatcg
    49861 ttccacagca cttcggcaat atcagccatg cccatcggcg cgccgggatg accagaattg
    49921 gctttttgta ccgcatccat actgagtgcg cgaatcgcat tggcaaggtc ttttcgggac
    49981 atataacact ccgtggctgg tttatagttt ggcggcaaga agatcttcca gtttgcgttg
    50041 atcaacagcg aacagacgaa tgccttcaga cagtttttct accgccatcg catcctgatt
    50101 gtgctcccaa cggaactccg cttcgctcat gggagctggg cgtgggaacg tctgagaagg
    50161 tgggattaat ttacgtacca ctggcgaaac tttttcctgc agctccttca gcaaattcgg
    50221 tgcgatagtc agtcgatcgc agccggttaa ggcgaggatt tgttcggtgc gacggaagct
    50281 cgcgcccatc acaatggttt catagtggtg ttgcttatag tagtcgtaga tattgcgcac
    50341 cgatttaacg cccggatctt cttccaccac atacgggtcc atcggcttgc gtgcctgata
    50401 ccagtcataa atacgcccga caaacggcga aatcagaaaa acgcccgctt ctgcacaggc
    50461 ccgcgcctgg gcaaaagaaa acagcagcgt caggttgcag ttaatacctt ctttttccag
    50521 ctcttcggcc gcgcgaattc cttcccaggt cgaagccagt ttgatcaaaa tgcgtgattt
    50581 ctcaacgcct tgttgctgat acaagtccac cagatggcgc gccttctcaa tactcttttc
    50641 tttatcaaaa gagaggcgtg catcaacttc tgttgacacg cgaccgggta cgattttgag
    50701 gatttcagca ccgaaattga ccgccagttt gtcacacgct gcgaccacct gttgttcctg
    50761 ggtcttgcca ttttttttac cccaggcgat agcatcgtct attaaatgct catattgtga
    50821 taatccggca gccttgagta acagcgaagg attggtggtg gcatcctggg gatgataatg
    50881 gcgaatggac tcaatatcgc cgctgtctgc cacgacagtg gtgaactgtt tgatgccgtc
    50941 taactcgttc ataggaaata ctccttgaaa agtaaagtgt tagatgagtg cgttaattca
    51001 cacttctgag aaatttcgct aaacgcatca aaaaagcata gcagacaggc atggtattgc
    51061 tggattaagc aggtaacatc agtgttatag gattattacc aaaacattat attaatggtg
    51121 agagtttgga cttgctcaaa gtctgtagac tccggcaagg taataatgtg cgccacgttg
    51181 tgggcagggg ctgttgccca cacactttat ttgtgaacgt tacgtgaaag gaacaaccaa
    51241 atggatgacc agttaaaaca aagtgcactt gatttccatg aatttccagt tccagggaaa
    51301 atccaggttt ctccaaccaa gcctctggca acgcagcgcg atctggcgct ggcctactca
    51361 ccaggcgttg ccgcaccttg tcttgaaatc gaaaaagacc cgttaaaagc ctacaaatat
    51421 accgcgcgcg gtaacctggt ggcggtgatc tctaacggta cggcggtgct ggggttaggc
    51481 aacattggcg cgctggcagg caaaccggtg atggaaggca agggcgttct gtttaagaaa
    51541 ttcgccggga ttgatgtatt tgacattgaa gttgacgaac tcgacccgga caaatttatt
    51601 gaagttgtcg ctgcgctcga accgaccttc ggcggcatca acctagaaga cattaaagcg
    51661 ccagaatgtt tctatattga acagaaactg cgcgagcgga tgaatattcc ggtattccac
    51721 gacgatcagc acggcacggc aatcatcagc actgccgcca tcctcaacgg cttgcgcgtg
    51781 gtggagaaaa acatctccga cgtgcggatg gtggtttccg gcgcgggtgc cgcagcaatc
    51841 gcctgtatga acctgctggt agcgctgggt ctgcaaaaac ataacatcgt ggtttgcgat
    51901 tcaaaaggcg ttatctatca aggccgtgag ccaaacatgg cggaaaccaa agccgcatat
    51961 gcggtggtgg atgacggcaa acgtaccctc gatgatgtga ttgaaggcgc agatattttc
    52021 ctcggctgtt ccggcccgaa agtgctgacc caggaaatgg tgaagaaaat ggctcgggca
    52081 ccaatgatcc tggcgctggc gaacccggaa ccggaaattc tgccgccgct ggcgaaagaa
    52141 gtgcgtccgg atgccatcat ctgtaccggc cgttccgact acccgaacca ggtgaacaac
    52201 gtcctttgct tcccgttcat cttccgtggc gcgctggacg ttggcgcaac cgccatcaac
    52261 gaagagatga aactggcggc ggtacgcgcg attgcagaac tggcccatgc ggaacagagc
    52321 gaagtggtgg cttcagcgta tggcgatcag gatctgagct ttggtccgga atacatcatt
    52381 ccaaaaccgt ttgatccgcg cttgatcgtt aagatcgctc ctgcggtcgc gaaagcggcg
    52441 atggagtcgg gcgtggcgac gcgtccgatt gctgatttcg acgtctacat cgacaagctg
    52501 actgagttcg tttacaaaac caacctgttt atgaagccga ttttctccca ggctcgcaaa
    52561 gcgccgaagc gcgtagttct gccggaaggg gaagaggcgc gcgttctgca tgccactcag
    52621 gaactggtaa cgctgggact ggcgaaaccg atccttatcg gtcgtccgaa cgtgatcgaa
    52681 atgcgcattc agaaactggg cttgcagatc aaagcgggcg ttgattttga gatcgtcaat
    52741 aacgaatccg atccgcgctt taaagagtac tggaccgaat acttccagat catgaagcgt
    52801 cgcggtgtca ctcaggaaca ggcgcagcgt gcgctgatcg gtaacccgac agtgatcggc
    52861 gcgatcatgg ttcagcgtgg ggaagccgat gcaatgatct gcggtacggt gggcgattat
    52921 catgaacatt ttagcgtggt gaaaaatgtc tttggttatc gcgatggcgt tcacaccgca
    52981 ggtgcaatga acgcgctgct gctgccgagt ggtaacacct ttattgccga tacctacgtc
    53041 aatgacgaac cagacgcaga agagctggcg gagatcacct tgatggcggc agaaactgtc
    53101 cgtcgtttcg gtattgaacc gcgcgttgct ctgttgtcgc actccaactt tggttcttct
    53161 gactgcccgt cgtcgagcaa aatgcgtcag gcgctggaac tggtcaggga acgtgcgcca
    53221 gaactgatga ttgatggtga aatgcacggc gatgcagcgc tggtggaagc gattcgcaac
    53281 gaccgtatgc cggacagccc tttgaaaggt tctgccaata ttctggtgat gccaaacatg
    53341 gaagctgccc gcattagtta caacttactg cgcgtttcca gctcggaagg tgtgactgtc
    53401 ggtccggtgc tgatgggcgt ggcgaaaccg gttcacgtgt taacgccgat cgcatcggtg
    53461 cgtcgtatcg tcaacatggt ggcgctggcc gtggttgaag cgcaaaccca accgctgtaa
    53521 ttctttttta actctcacgc ttaccctgaa tattcagggt aagcggtttg gctgcaatat
    53581 attagtaaag cttattactg agtttgcgaa taataaaaaa agcagtctat ataatatctc
    53641 gatattattt tatttatatt catgcgttgc atatgaaagt ttatgcacca cagcgaatat
    53701 ctctccattc ttagtgatct acctcacctt ttaaacgcgc ttgccgaatt ttgttattta
    53761 ctctgacgaa aaattgtcac gatacacgca agtttttcac aggcggcgac tcatggataa
    53821 agaacgcatc attcaggaat ttgtgcccgg caaacaggtc acgctggcgc atctcatcgc
    53881 gcatcccggc gaggaactgg cgaagaaaat cggcgttccg gatgctgacg caatcggcat
    53941 tatgacgcta actcctggcg aaacggcgat gatcgccggt gatttagcac tgaaagccgc
    54001 cgatgtgcat atcggttttc tcgaccgctt cagtggtgca ttggtgattt atggctcggt
    54061 gggtgcagta gaagaagcgt tatcacaaac cgtcagtggt ttaggtcgct tattaaatta
    54121 tacgctttgt gaaatgacca aaagttaata cgaggcattc atgaaacgaa ttgcgtttgt
    54181 gggtaccgtc ggggcaggga aaacaacgtt atttaatgcg ttgcagggga attataccct
    54241 cgccagaaaa acacaggccg tggaatttaa tgataagggc gatattgata cgccgggtga
    54301 atattttagc catccccgct ggtatcacgc cttaattacc acgctacagg atgtggacat
    54361 gctgatctat gtccacggcg cgaatgaccc ggaaagtcgg ttgcctgccg ggttgctgga
    54421 tattggcgtc agcaaacggc aaatcgccgt catcagtaaa acggacatgc cagatgctga
    54481 cgtcgccgca acgcgaaagt tattgcttga gactggcttc gaagagccga ttttcgagct
    54541 aaacagccac gacccgcaaa gcgtgcagca actggtggat tatctggcat ctctcaccaa
    54601 acaggaggaa gcaggtgaaa aaactcatca cagcgaatga tattcgtgaa gcacacgcgc
    54661 gcggcgaaca ggcaatgtcc gtggttctgc gcgccagcat tattaccccg gaagcccgtg
    54721 aagtggcgga tctactgggt tttaccatca ccgaatgtga tgaatcgtcc ccggtaacgg
    54781 cgtccgttcc cgccagcgtg ccagccgata aaaccgaaag ccagcgcatc cgcgaaacca
    54841 ttatcgccca actgccggaa ggccagttta ccgaaagcct ggtcgcgcag ttgatggaaa
    54901 aagtgatgaa ggaaaaacag tcgctggagc agggtgcaat gcagccgagc ttcaaatcgg
    54961 tgaccggcaa aggcggcatc aaagtgattg atggcagcag cgtcaagttt ggtcgtttcg
    55021 acggcgcaga gccgcattgc gtgggcttaa ctgaccttgt gaccggagac gacggcagca
    55081 gcatggccgc tggttttatg cagtgggaca acgcattctt cccgtggacc ctgaactacg
    55141 acgaaatcga tatggttctg gaaggggagc tgcatgttcg ccacgaaggc gaaaccatga
    55201 tcgccaaagc aggcgacgtg atgtttatcc cgaaaggctc cagtatcgaa tttggtacga
    55261 catccagcgt gaaattcctg tatgtcgcct ggcctgctaa ctggcaatcc ctatgaaaga
    55321 tttcatcacc gaagcatggc taagagcgaa ccatacgctc agcgaaggcg cagagatcca
    55381 tctccctgcg gacagtcgcc tgacgccctc tgcccgggag ttactggaaa gccgccatct
    55441 gcgcatcaag tttattgacg agcagggccg cctgtttgtt gacgatgagc agcagcagcc
    55501 acagcccgtt cacgggctga ccagtagcga tgaacatccg caggcgtgct gcgaactgtg
    55561 ccgccagccg gtggcaaaaa agccggatac gctgactcat ctgtcggcgg aaaaaatggt
    55621 tgccaaaagc gatccgcgtc tgggttttcg cgcggttctc gacagcacca ttgcgctggc
    55681 agtgtggctg caaattgaac tggcggaacc gtggcagccg tggctggcgg atatccgttc
    55741 gcgtcttggc aacattatgc gtgccgatgc gctgggggaa ccgctgggct gccaggcgat
    55801 tgtcgggctt tctgacgaag atctgcaccg gctttctcat cagccgttgc gttatcttgg
    55861 tcacgatcat ctggtgccgg aagccagcca cgggcgcgat gcggcgttgc tcaatctgct
    55921 acgcaccaaa gtgcgggaaa ccgaaaccgt agcggcgcag gtgtttatca cccgcagctt
    55981 tgaagtatta cgcccggaca tcttgcaggc gctgaaccgc ctttccagca cggtctacgt
    56041 gatgatgatc ctgagcgtaa cgaagccgcc gctaacggtg aagcagatcc aacaacgact
    56101 gggggaaacg caatgattat tgaacgttgt cgtgaactgg cgttgcgagc gcccgccaga
    56161 gtggtttttc cggatgcgtt agatcaacgt gtgctgaaag ctgcgcaata tttacatcaa
    56221 caaggtctgg caacgcccat tctggtcgcc aatccgtttg aacttcgtca gtttgcgctc
    56281 agtcacggcg tggcgatgga cgggctacag gtgattgatc cgcatggcaa cctcgcaatg
    56341 cgggaagaat ttgctcatcg ctggctggcc cgcgcgggcg aaaaaacgcc gccggatgcg
    56401 ctggaaaaac ttaccgatcc gctgatgttc gccgccgcaa tggtcagcgc cggtaaagcg
    56461 gatgtctgta tcgcgggcaa cctctcttcc acggcgaatg tgctgcgtgc cggattacgc
    56521 attattggct tgcaacctgg ctgtaaaacg ctctcttcca ttttcctgat gctgccacag
    56581 tatagtggcc ccgcgttggg ctttgccgat tgcagcgtgg taccacagcc gacggcggcg
    56641 cagctggcgg atatcgcgct tgccagcgcc gaaacctggc gcgccatcac cggagaagag
    56701 ccgcgcgtgg cgatgctgtc gttttccagt aacggtagcg cccgtcaccc ctgcgttgcc
    56761 aatgtccagc aggcgacaga aatcgtccgt gagcgcgcac caaagctggt agtcgatggc
    56821 gagttgcagt ttgacgccgc cttcgtgccg gaagtggcgg cgcaaaaagc gcctgccagc
    56881 ccgctacagg gcaaagctaa tgtgatggtt tttccgtcgc tggaagccgg aaatattggt
    56941 tacaaaatcg cacagcgact tggcggatat cgtgccgtcg ggccattgat acaaggactt
    57001 gccgcgccga tgcacgatct ctctcgtggt tgtagtgtgc aggaaattat cgagctggcg
    57061 ctggtggcag ctgtgccgcg tcagacagaa gtgaaccgcg aaagcagttt acaaacactg
    57121 gttgaatgaa cggtcccgtt ctggaccctg ataaagagga aagcacaatg gaagcattag
    57181 gaatgatcga aacccggggc ctggttgcac tgattgaggc ttctgacgcg atggtgaaag
    57241 ctgcgcgcgt caagctggtt ggtgttaagc agattggcgg cggcctgtgt actgccatgg
    57301 ttcgtggtga tgttgcagcc tgtaaagcgg cgaccgatgc cggtgccgca gcggcacagc
    57361 gtatcggcga gctggtatct gtacacgtta tcccgcgtcc gcacggcgac ctggaagaag
    57421 tgttcccgat cggcctgaaa ggcgatagca gcaacctgta atcaccctgt gtgacgtcga
    57481 ttcgggcgtc acgctctctc ctttttcatt ttaccttccg cggagggtag ggggagcttt
    57541 tacctgaaat acgccacgga ggcgggtatg aaactggcag tcgtcactgg acaaattgtt
    57601 tgtaccgtac gccatcacgg actggcgcat gacaaattgc tgatggtgga aatgattgat
    57661 ccacaaggta atcctgacgg gcaatgtgcc gtcgccatcg acaatattgg cgcgggaacc
    57721 ggggagtggg tgttgctggt gagtggcagt tccgcccgcc aggcgcataa aagcgaaacg
    57781 tcaccggtcg atctgtgcgt gattggcatc gtcgatgagg tggtgtctgg cggtcaggta
    57841 attttccaca aataaggcag aacatcatga atcaacagga tattgaacag gtggtgaaag
    57901 cggtactgct gaaaatgcaa agcagtgaca cgccgcccgc cgccgttcat gagatgggcg
    57961 ttttcgcgtc cctggatgac gctgttgcgg cagccaaaat tgcccagcaa gggttaaaga
    58021 gcgtggcaat gcgccagtta gccattgctg ccattcgtga agcaggcgaa aaacacgcca
    58081 gagatttagc ggaacttgcc gtcagtgaaa ccggcatggg gcgcgttgaa gataaatttg
    58141 caaaaaacgt cgctcaggcg cgcggcacac caggcgttga gtgcctctct ccgcaagtgc
    58201 tgactggcga caacggcctg accctaattg aaaacgcacc ctggggcgtg gtggcttcgg
    58261 tgacgccttc cactaacccg gcggcaaccg taattaacaa cgccatcagc ctgattgccg
    58321 cgggcaacag cgtcattttt gccccgcatc cggcggcgaa aaaagtctcc cagcgggcga
    58381 tcacgctgct caaccaggcg attgttgccg caggcgggcc ggaaaactta ctggttactg
    58441 tggcaaatcc ggatatcgaa accgcgcaac gcttgttcaa gtttccgggt atcggcctgc
    58501 tggtggtgac cggcggcgaa gcggtagtag aagcggcgcg taaacacacc aataaacgtc
    58561 tgattgccgc aggcgctggc aacccgccgg tagtggtgga tgaaaccgct gacctcgccc
    58621 gtgctgctca gtccatcgtc aaaggcgcgt ctttcgataa caacatcatt tgtgccgacg
    58681 aaaaggtact gattgttgtt gatagcgtag ccgatgaact gatgcgtctg atggaaggcc
    58741 agcacgcggt gaaactgacc gcagaacagg cgcagcagct gcaaccggtg ttgctgaaaa
    58801 atatcgacga gcgcggaaaa ggcaccgtca gccgtgactg ggttggtcgc gacgcaggca
    58861 aaatcgcggc ggcaatcggc cttaaagttc cgcaagaaac gcgcctgctg tttgtagaaa
    58921 ccaccgcaga acatccgttt gccgtgactg aactgatgat gccggtgttg cccgtcgtgc
    58981 gcgtcgccaa cgtggcggat gccattgcgc tagcggtgaa actggagggc ggttgccacc
    59041 acacggcggc aatgcactcg cgcaacatcg aaaacatgaa ccagatggcg aatgctattg
    59101 ataccagcat tttcgttaag aacggaccgt gcattgccgg gctggggctg ggcggggaag
    59161 gctggaccac catgaccatc accacgccaa ccggtgaagg ggtaaccagc gcgcgtacgt
    59221 ttgtccgtct gcgtcgctgt gtattagtcg atgcgtttcg cattgtttaa ggagtaaccg
    59281 atggcgcacg acgaacaatg gctcacccca cgtctgcaaa cggcggcaac gctgtgtaac
    59341 cagacgcccg ccgcgacgga atctccgctg tggctggggg tggatctggg cacatgcgat
    59401 gtggtgtcga tggttgtcga ccgcgagggt cagccagtgg cggtatgcct cgactgggcc
    59461 gatgtggttc gcgacggcat cgtctgggat ttcttcggcg ctgtcaccat tgttcgtcgc
    59521 catctcgaca ctcttgagca gcaattcggt cgccgtttta gccatgcggc gacttcattt
    59581 cctccaggta cggacccgcg tatttccatc aacgtgctgg agtctgctgg actggaagtg
    59641 agccatgtgc tggatgagcc aaccgcagtc gcggatctgc tgcaactgga caacgccggt
    59701 gtagtggata tcggcggcgg cactaccggc attgccatcg tgaaaaaggg caaggtgacg
    59761 tactcggcgg atgaagcaac cggcggacat cacatctctc tgactctcgc cggaaatcgc
    59821 cgtatttcgc tggaagaggc agagcagtac aagcgcggtc acggtgacga gatttggccc
    59881 gcggtgaaac cggtgtacga aaaaatggcg gacattgtcg cccggcatat tgaaggacag
    59941 ggcattactg atttatggct ggcgggcggc tcctgtatgc agccgggcgt ggcggaactg
    60001 tttcgcaaac aattcccggc gttacaggtg catttaccgc agcacagttt gtttatgacc
    60061 ccgctggcga tcgccagtag tgggcgagag aaagcggagg ggctatatgc aaaatgaatt
    60121 gcagaccgcg ctctttcagg cgttcgatac cctgaatctg caacgggtaa aaacatttag
    60181 cgttccaccg gtgacgcttt gcggtccggg ctcggtgagc agttgcggac agcaagcgca
    60241 aacgcgtggg ctgaaacatc tgttcgtgat ggcagacagc tttttgcatc aggcagggat
    60301 gaccgccggg ctgacgcgta gcctggccgt taaaggtatc gccatgacgc tctggccatg
    60361 tccggtgggc gaaccgtgca ttaccgacgt gtgtgcagcc gtggcgcagt tgcgtgagtc
    60421 aggttgtgac ggggtgatcg catttggcgg cggctcggtg ctggatgcgg cgaaagccgt
    60481 ggtgttgctg gtgacgaacc cggatagcac gctggcagag atgtcagaaa ccagcgttct
    60541 gcaaccgcgc ttgccgctga ttgccattcc aactaccgcc ggaaccggct ctgaaaccac
    60601 caatgtaacg gtgattatcg acacggtgag cgggcgcaag caggtgttag cccatgcctc
    60661 gctgatgccg gatgtggcga tcctcgacgc cgcattgacc gaaggtgtgc cgtcgcatgt
    60721 cacggcgatg accggcattg atgcgttaac ccatgccatt gaagcataca gcgccctgaa
    60781 cgctacaccg tttaccgaca gtctggcgat tggtgccatt gcgatgattg gcaaatcgct
    60841 gccgaaagcg gtgggctacg gtcacgacct tgccgcgcgc gagagcatgt tgctggcttc
    60901 atgtatggcg ggaatggcgt tttccagtgc gggtcttggg ttgtgccacg cgatggcgca
    60961 tcagccgggc gcggcgctgc atattccaca cggtctcgcg aacgctatgt tgctgccaac
    61021 ggtgatggag tttaaccgga tggtttgtcg tgaacgcttt agtcagattg gtcgggcact
    61081 gcgaactaaa aaatccgacg atcgtgacgc tattaacgcg gtaagtgagc tgattgcgga
    61141 agttgggatt ggtaaacgac tgggcgatgt tggcgcgaca tctgcgcatt acggtgcatg
    61201 ggcgcaggcc gcgcaggaag atatttgtct gcgcagcaac ccgcgtaccg ccagcctgga
    61261 acagattgtc ggcctgtacg cagcggcgca ataaatgccg gatgcgacgc atgtcgcgtc
    61321 ttatccggcc tacgggattg cacatgtagg gcggataagg cgttcacgcc gcatccgcta
    61381 ataaataaca actaacaggg agtaaaggcg atgggaatta acgaaatcat catgtacatc
    61441 atgatgttct ttatgctgat agctgccgta gacaggatcc tgtcacagtt cggcggttct
    61501 gctcgtttcc tcggtaagtt cggtaaaagt atcgaaggat caggcggtca gttcgaagaa
    61561 ggctttatgg caatgggcgc actgggcctg gcgatggtcg gtatgaccgc gctggcaccg
    61621 gtactggctc acgtactcgg gccggtaatt atcccggttt acgaaatgct cggcgcaaac
    61681 ccgtcaatgt tcgccggaac gctgctggcg tgcgatatgg gcggcttctt cctcgccaaa
    61741 gagctggcgg gcggcgacgt agcagcgtgg ctatactctg ggttaattct cgggtcgatg
    61801 atggggccaa cgattgtgtt ttccattccg gtggcgctcg gcattatcga accttctgac
    61861 cgtcgttatc tggcgctcgg cgtgctggcg ggcattgtga ccattccgat tggttgtatc
    61921 gctggtggtc tggtagctat gtactccggt gtgcagatca acggccagcc ggtggaattc
    61981 actttcgccc tgatcctgat gaacatgatc ccggtgatca ttgttgcgat tctggtggcg
    62041 ctggggctga aattcatccc ggaaaaaatg atcaacggct tccagatctt cgccaaattc
    62101 ctcgttgcat tgatcaccct cggtcttgcc gctgcggtag tgaaattcct gcttggctgg
    62161 gaactgatcc ccggtctgga tcctatcttt atggcccctg gcgataaacc cggtgaggtg
    62221 atgcgcgcca ttgaagttat cggttctatc tcctgcgttc tgttaggggc gtatccaatg
    62281 gtgctgctgc tgacccgctg gtttgaaaaa ccgctgatga gcgtcggtaa agtgctgaat
    62341 atgaacaaca tcgcggcagc cggcatggtg gcaacgcttg ccaacaacat cccgatgttc
    62401 ggcatgatga agcagatgga tacccgcggc aaagtcatca actgcgcctt cgccgtttcc
    62461 gctgctttcg ccctgggcga ccacttaggc ttcgccgctg ccaacatgaa tgccatgatc
    62521 ttcccgatga ttgtcggcaa gttgatcggc ggcgtaacgg cgattggcgt ggcgatgatg
    62581 ctggtgccaa aagacgacgc gaccgcggct aaaaccgaag cggaggcaca atcgtgaaca
    62641 ctcgccagct actgagcgtc ggtatcgata tcggcaccac caccacccag gtgattttct
    62701 cccacctgga actggttaac cgtgcggcgg tgtcgcaggt gccgcgctac gaattcatca
    62761 aacgcgaaat tagctggcaa agcccggtgt tctttacccc tgtcgataaa cagggtggtt
    62821 taaaagaagc ggaactgaaa tcgctgattt tagagcaata tcaggctgcg ggaattgcgc
    62881 cggaaagcgt tgattctggt gccatcatca tcaccggtga aagcgcgaaa acccgcaatg
    62941 ctcgcccggc ggtgatggcg ctctctcagt cgctgggcga ttttgtcgtc gccagcgccg
    63001 ggccgcacct cgaatccgtg atcgccggtc acggtgccgg ggcgcaaacc ctttctgaac
    63061 aacggctgtg tcgggtactg aatatcgaca tcggcggtgg caccgcgaac tacgccctgt
    63121 tcgatgccgg aaaaatcagc ggcactgcct gcctcaacgt cggtggtcgc ctgctggaaa
    63181 ccgacagcca ggggcgcgtg gtttacgctc ataaaccggg gcagatgatt gtggatgagt
    63241 gtttcggtgc aggcactgac gtccgttcgc tgaccggcgc gcagctggtg caggttaccc
    63301 ggcggatggc agaactgatt gtcgaagtga ttgacggaac gctctcaccg ctcgcgcagg
    63361 cattgatgca aaccggtttg ctgcccgcag gtgttacgcc cgaaatcatt acgctttctg
    63421 gcggcgtggg cgaatgttat cgccaccagc ccgccgaccc gttctgtttt gccgatattg
    63481 gcccacttct ggcaacggcg ctgcatgacc atccgcgcct gcgtgagatg aatgtgcagt
    63541 ttccggcgca aaccgtacgc gccacggtga ttggcgcggg tgcacatacc ctttcgctct
    63601 ctggcagcac aatctggctg gagggcgtac aactgccgct gcgcaatttg ccggtggcga
    63661 tcccgattga tgaaacggat ctggtgggtg cctggcaaca ggcgctgatt cagctggatc
    63721 ttgatcccaa aactgacgcg tacgtgctgg cgcttcccgc ctcgctgcct gtgcgttacg
    63781 ccgcggtact gacggtcatc aacgcgttgg tcgatttcgt cgcgcgtttt ccgaatccgc
    63841 atcccctgct ggtggtggcc gggcaggact ttggtaaagc tctgggcatg ttgttgcgcc
    63901 cacagctaca acaactcccg ttggcagtca ttgacgaagt gattgtccgc gcgggggact
    63961 atatcgacat tggtacgcct ctttttggcg gatcggttgt gccggtgacg gtgaaatcac
    64021 tcgcatttcc ttcctgaggg aacgacttat gaaactaaag accacattgt tcggcaatgt
    64081 atatcagttt aaggatgtaa aagaggtgct ggctaaagcc aacgaactgc gttcggggga
    64141 tgtgctggca ggcgttgcag cggcaagttc acaggagcgc gtggcggcaa agcaggtgtt
    64201 gtcggaaatg accgtagcgg acatccgcaa taatccggtg attgcctatg aagatgactg
    64261 cgtgacgcgg ctgattcagg acgatgttaa cgaaacggcc tacaaccaga ttaaaaactg
    64321 gagcatcagc gaactgcgtg agtatgtgct gagcgatgaa accagcgtgg acgacattgc
    64381 ctttacccgc aaagggctga cctcggaagt ggtcgcggcg atagcgaaga tttgctccaa
    64441 cgcggacctg atctacggcg cgaagaaaat gccggtaatc aaaaaggcca ataccaccat
    64501 cggtattccg ggcaccttca gcgcccgttt gcagccaaat gacacccgtg acgacgtgca
    64561 aagtatcgcc gcgcaaatct acgaagggct ttccttcggg gtgggcgatg cggtgatcgg
    64621 cgtcaacccg gtaactgacg acgtggaaaa cttaagccgc gtgctggaca ccatctatgg
    64681 cgtgatcgac aaattcaaca tcccaactca gggctgcgta ctggcgcacg tcaccaccca
    64741 gatcgaagcg attcgtcgtg gcgcaccagg cgggctgatt ttccagagta tctgtggcag
    64801 tgaaaaaggg ctgaaagagt ttggcgtgga actggcgatg ctcgacgaag cgcgcgcagt
    64861 gggtgcagag ttcaaccgta tcgccgggga aaactgcctc tacttcgaaa ccggacaagg
    64921 ttcagcgcta tccgctggcg ctaactttgg cgcagaccag gtgacgatgg aagcacgtaa
    64981 ctatgggctg gcgcgtcatt acgatccgtt tatcgtcaac accgtggtcg gctttattgg
    65041 gccggagtat ctctacaacg accgccagat tatccgtgcg ggcttagaag atcactttat
    65101 gggcaagctg agcggcatct ctatgggctg tgactgctgt tacaccaacc acgctgacgc
    65161 tgaccagaac ctcaacgaaa acctgatgat cctgctcgcc accgcaggct gcaactacat
    65221 catggggatg ccgctgggtg atgacatcat gctcaactac cagaccaccg cattccacga
    65281 taccgccact gtgcgtcagt tactcaacct gcgcccgtca ccggagtttg aacgctggct
    65341 ggaaagcatg ggcattatgg caaacggtcg cctgaccaaa cgggcgggcg atccgtcact
    65401 gttcttctga tgacgcggag ataacacatc atggatcaaa aacagattga agaaattgta
    65461 cgcagcgtga tggcgtcaat gggacaagcg gcccccgcgc cgtcagaagc aaagtgcacc
    65521 accaccacct gtgcggcacc ggtgacctcg gaaagctgtg cgctggattt aggttctgcg
    65581 gaagcaaaag cgtggattgg tgttgaaaac ccacatcgtg cggatgtgtt aacagaactg
    65641 cgtcgcagca ccgtggcccg cgtttgtacc ggtcgtgccg gtccgcgtcc gcgtacccag
    65701 gcgttgctgc gtttcctggc cgatcactct cgttcgaaag ataccgtact taaagaagtg
    65761 ccggaagagt gggtgaaagc gcagggcttg ctggaagtac gctctgaaat tagcgacaaa
    65821 aatctctacc tgactcgccc ggatatgggc cgccgcctgt gtgcagaagc tgttgaagcg
    65881 ctgaaagcgc agtgtgttgc caatccggac gtacaggtcg ttatttctga tggcctgtca
    65941 actgatgcca tcactgtgaa ctacgaagag atcctgccgc cgctgatggc gggcctgaaa
    66001 caggccgggc tgaaagtcgg cacgccattc tttgttcgtt atggtcgcgt gaagattgaa
    66061 gatcagatcg gtgagatcct cggcgcgaaa gtggtgatcc tgctggtggg ggaacgtccg
    66121 gggttagggc agtcagaaag cctctcctgc tacgccgttt actcgccgcg tatggcgacc
    66181 accgttgagg ccgatcgcac ctgcatctct aacattcacc agggcggcac gccgccggtt
    66241 gaagccgcag ccgtcattgt ggatttggcg aaacgtatgc tggagcagaa agcatccggc
    66301 atcaacatga cccgataagg aggcatcatg ccagctttag atttgattcg accgtctgtc
    66361 accgctatgc gggtgattgc ctccgttaac gccgattttg cgcgtgaact gaaattgccg
    66421 ccgcatattc gtagcctcgg tctgatttct gccgactccg atgacgtcac ctacattgcc
    66481 gctgatgaag cgaccaagca ggcgatggtg gaagtggtgt atggccgctc gctgtatgcg
    66541 ggcgctgcac acggcccgtc accgactgcc ggtgaagtgc tgattatgct tggtgggcca
    66601 aacccggcgg aagtgcgtgc cggtctggat gcgatggttg cgcatattga aaatggcgct
    66661 gctttccagt gggctaatga tgcgcaagat acggcattcc tggcacatgt agtttcgcgt
    66721 accggttctt atctctcatc aaccgccggg atcacgcttg gcgatccgat ggcgtatctg
    66781 gtggcaccgc cgctggaagc gacctacggc attgatgcag cgttgaaatc tgccgacgta
    66841 cagctggtga cctatgtccc gccaccgtct gaaactaact actcggcagc atttttaacc
    66901 ggtagccagg cagcgtgtaa agcggcctgt aacgccttta ccgatgcagt gctggaaatc
    66961 gcgcgtaatc caatccagcg tgcgtaatgg aggttgccga tgatcaatgc actgggattg
    67021 ctggaagtgg acggcatggt cgctgcgata gatgcagcgg atgccatgct caaagcagct
    67081 aacgttcgtc tgctcagtca cgaagtgctt gaccctggtc gcttaacgct ggtggtggaa
    67141 ggcgatctgg cggcgtgtcg tgctgcgctg gacgcaggtt gtgctgccgc gatgcgtacc
    67201 gggcgtgtca tcagccgtaa ggagatcggt cggccagacg atgacaccca gtggctggtt
    67261 actggcttta accgccagcc gaagcaaccc gtaaaggaac ccgacgcgcc agttatcgtt
    67321 gcggaatctg ctgacgagtt gttggcgctg ttaacatcag tacgtcaggg aatgacggca
    67381 ggagaagtgg ctgcccactt tggctggccg ctggaaaaag ccagaaatgc gctcgaacag
    67441 ctcttttctg ccgggacgtt acgtaaacgc agtagtcgtt atcgtctcaa gccccattaa
    67501 cctgtcggag gtgccgggtg tcctacaaca cccggcatta acatcatgaa aaagacccgt
    67561 acagccaatt tgcaccatct ttatcatgaa cccttacccg aaaacctgaa gctcacgccg
    67621 aaggtcgaag tggataatgt tcatcaacga cagacaacgg atgtctatga acatgcttta
    67681 acgattaccg cctggcagca gatttacgat cagctgcatc cgggcaagtt tcatggtgaa
    67741 tttacggaaa ttctactcga tgatattcag gtttttcgtg aatacaccgg tctggcgctg
    67801 cgtcagtcgt gtctggtctg gccgaactcg ttctggtttg gcattccggc gacgcgcggt
    67861 gagcagggat ttatcggttc gcaatgtctg ggaagcgcag aaatagcgac gcgccctggt
    67921 ggaaccgagt ttgaattaag tacgccggac gattacacga tcctgggcgt agtgctttct
    67981 gaagatgtca tcacccgtca ggctaacttt ttgcataatc cggatcgggt attacatatg
    68041 ttgcgtagcc agtcggcgct ggaagtgaaa gagcagcata aagccgcgct gtggggcttt
    68101 gtccaacagg cgctggcgac gttttgcgag aacccggaaa atcttcatca gcctgcagtg
    68161 cgaaaagtgc tgggggataa tttgctaatg gcgatggggg cgatgctgga agaagcgcaa
    68221 ccaatggtga cggcggaaag catcagtcat cagagttacc gtagattact ttcccgcgcc
    68281 cgtgaatatg tgctggaaaa catgtccgaa ccggtgacgg tgctggactt gtgtaatcaa
    68341 ctgcatgtca gccgccgcac gctacaaaac gcgtttcacg ctattttagg cattggcccg
    68401 aacgcgtggc tgaaacgcat tcgcctgaac gccgtacgcc gcgaactgat aagcccgtgg
    68461 tcgcaaagca caacggtaaa agacgccgcc atgcagtggg gattctggca tctggggcaa
    68521 tttgccacgg attaccagca gctgtttgcc gagaagccgt cgttgacgtt gcatcagcgg
    68581 atgcgggaat gggggtgagg gagttacacc caatccctga ccttaataaa ctcacttaac
    68641 gccgcttctg ggctgccatc ttttggctga taatcatact cccagcgtac cagtggcggc
    68701 attgacatca ggatcgactc ggtgcgcccg ccagtttgca ggccaaacag agtgccgcga
    68761 tcccagacca gattgaactc gacataacga ccgcgacggt agagctgaaa attgcgctcg
    68821 cgctcgccgt aggccatcgc tttacgtcgc tctacaattg gtaaataagc gtcggtgtag
    68881 cctttgccta ccgcctgcat aaaggcaaaa cagtggttga aatctggcgt gttcagatca
    68941 tcaaagaaca gcccgccaat accgcgctgt tcgttgcgat gtttgaggta gaagtaatcg
    69001 tcgcaccact ttttgtaacg gggataaacg tcttcaccaa atggcaggca caggtcacgg
    69061 gcggtgcggt gccagtgaat ggcgtcttct tcaaaaccat agaaaggggt taaatcgaag
    69121 ccgccgccaa accaccagac gggctctgca cccggttttt cggcaataaa aaagcgcaca
    69181 ttcgcgtggc tggtgggaac atacggatta tgcggatgca ctaccagcga aacgcccatc
    69241 gcctcgaaac tgcgcccggc aagttccggg cgatgagcgg tggcggaagc aggcatcgcc
    69301 tcaccgtgga catgtgaaaa gttgacgccc gcctgttcga aaacaccacc attacgcaac
    69361 acccgactac gcccgccgcc accagcttcg cgctgccagc tatcttcgac aaattctgtg
    69421 ccatcgacgg cggtcaactg ctgacaaatc gtatcctgaa ggttgagcag aaactgttta
    69481 acctggtgtg cgtcgggttt cataacttat cgctttttcg aatgtgcttt ctggttgtcg
    69541 aaccagtgga aataactgat cacgccttca gcaatcgctg tggcgatttt ctgacgaaac
    69601 gccgccgtgc ctaacagccg ctcttcttcc gggttggtga taaacgaggt ttccaccagc
    69661 accgaaggaa ccgacggcga tttcaacacc acaaacgcgg cttgttcggt gttgcggctg
    69721 tgcagtttat gcaccggctt aatctttttc agaatatgcg agccaagcgt caggctgttt
    69781 ttaatagtat cggtttgcac cagatcaaac agcacttgct gcaataggtg atccttgtca
    69841 gtcgcctttt taccggcaac ttcatcggcg cggttttcgc gttcagacag gtatttcgcc
    69901 attgcgctac ttgccccacg gttagagagg gcaaataccg aagcaccggc agctttcggg
    69961 ttggtaaagc catcggcatg aattgacata aacagatctg cgccatgttt atgggcgatt
    70021 tcaacgcgat cgtaaagtgg gataaacgta tcgccagaac gcgttaaacg cgcatcaatc
    70081 ccatgattac gcaaaatgga acggacgttt ttagcaatcg ccagcaccac atgtttttct
    70141 ttcgaaccgt tgcgcccgat cgctccggta tcaatcccgc cgtggcctgg atcgagaaca
    70201 acgacacgtt tgccgccaga ttttttagct ttcggcttgc tgtgtccatt gctggttttt
    70261 aaaggttcgt ctttggcgat ggcttgcgac attcctgaca acgtcagggc agccaaaccg
    70321 gctttcagca cctggcggcg cgaagtgagt gtttttagtg gtttaaaagt gctcatacgg
    70381 cctgagttgt aataataaag ttccagatgt tatatcgtat cgcgtaatcc gttacgaccg
    70441 tttgctgttg agaattgttt tacttttcat ttcaatagtt gacaactccc cattatgcca
    70501 ctttttcaac cgattttcgt cagatattgg ctaattcgac cgttcacgcc ataatcagcc
    70561 ttttaacccg caaaaaggta acgaatacca tggagatacg cgtatttcgc caggaagatt
    70621 tcgaagaggt catcaccctt tgggagcgtt gcgacttgct gcgtccgtgg aacgatccgg
    70681 aaatggacat cgagcgtaag atgaaccatg acgtcagttt gtttctggtc gctgaggtaa
    70741 acggtgaagt ggtcggaacg gtgatgggcg gttatgacgg gcatcgcggg tctgcttatt
    70801 atcttggcgt gcatccagag tttcgtgggc gtggaattgc caatgcgttg cttaaccggc
    70861 tggagaaaaa gctgattgct cgcggctgcc cgaaaattca gatcaacgtg ccggaagata
    70921 acgacatggt gctcggaatg tatgaacgcc tgggatatga acacgccgac gtgctgagtc
    70981 tgggtaagcg tttgattgaa gatgaagagt actgagtttc atcctgtcca ttatgatgcg
    71041 cacggtcgcc tgcgtttacc cttgctcttc tggcttgtgc tattgcttca ggcgcgaacc
    71101 tgggtgctgt ttgtcattgc cggtgcgtcg cgcgagcagg gtactgcgct gctaaatctg
    71161 ttttatcccg atcacgataa tttctggctg gggctgattc ctggcattcc ggcggtgctg
    71221 gcgtttttgt tgagcggtcg gcgggctacg tttcctcgca cctggcgtgt actctatttt
    71281 ctgttgctgt tggcgcaggt ggttttactt tgctggcaac cgtggctgtg gctgaacggt
    71341 gaatccgtta gcggtatcgg tctggcgctg gtagtggcgg atattgtggc gttaatctgg
    71401 ctgctgacca atcgacgttt acgcgcttgt tttaatgaag aaaaagaata acgcagaggt
    71461 gcgctttgtt tatgccggat gcggcgtgaa cgccttatcc ggcctacaaa atttcgcaaa
    71521 ttcaatatat tgcaggaaaa agtaggcctg ataagcgtag cgcatcaggc aattttgtgt
    71581 ttgtcatcag cctctggcgg cacttttttg caaattagca ctccaagcaa cgttattgaa
    71641 taaccaaagg aagtgacatg aaatcgctgc gtttattgtt atgcgctatg ccgttgatgc
    71701 taactggctg ttccactatg tcgtcagtta actggtctgc cgctaacccg tggaactggt
    71761 ttgggtcgtc caccaaagtg agcgagcagg gcgttggtga attaacggcg tccacaccac
    71821 tgcaagaaca agccattgcc gatgcgcttg atggcgatta tcgcctgcgc agcggaatga
    71881 aaaccgcgaa cggcaacgtg gtgcgctttt ttgaagtgat gaagggcgac aacgtggcga
    71941 tggtgattaa cggcgatcaa ggcacgatca gtcgcattga cgtgctggat agcgatattc
    72001 ctgctgacac cggtgttaaa atcggtacac cgtttagcga cctttacagc aaagcatttg
    72061 gcaattgcca aaaagctgat ggtgatgata atcgtgccgt cgaatgtaaa gccgaaggca
    72121 gtcaacatat tagctaccag ttcagcgggg aatggagtgg tcctgaaggg ttaatgcctt
    72181 cggacgatac cctgaaaaac tggaaagtca gtaaaattat ctggcggcgt taatttgcgt
    72241 ctgaacaaac cgccgccgcg aaaaaacacg taaaatagcg ctcaacaatg ccacggattg
    72301 cgtggcatta ttattttcag gaggaacaat gtctcaggtt cagagtggca ttttgccaga
    72361 acattgccgc gcggcgattt ggatcgaagc caacgtgaaa ggggaagttg acgccctgcg
    72421 tgcggccagt aaaacatttg ccgacaaact ggcaactttt gaagcgaaat tcccggacgc
    72481 gcatcttggt gcggtggttg cctttggtaa caacacctgg cgcgctctga gcggcggcgt
    72541 tggggcagaa gagctgaaag attttccggg ctacggtaaa ggccttgcgc cgaccaccca
    72601 gttcgatgtg ttgatccaca ttctttctct gcgtcacgac gtaaacttct cagtcgctca
    72661 gatggcgatg gaagcctttg gtgattgcat tgaagtgaaa gaagagatcc acggcttccg
    72721 ttgggttgaa gagcgtgacc tgagcggctt tgttgacggt acggaaaacc cggcgggtga
    72781 agagacgcgt cgcgaagtgg cggttatcaa agacggcgtg gatgcgggcg gcagctatgt
    72841 gtttgtccag cgttgggagc acaacctgaa gcagctcaac cggatgagcg ttcacgatca
    72901 ggagatgatg atcgggcgca ccaaagaggc caacgaagag attgacggcg acgaacgtcc
    72961 ggaaacctct cacctgaccc gcgttgatct gaaagaagat ggcaaagggc tgaagattgt
    73021 tcgccagagc ctgccgtacg gcaccgccag tggcactcac ggtctgtact tctgcgccta
    73081 ctgcgcgcgt ctgcataaca ttgagcagca actgctgagc atgtttggcg ataccgatgg
    73141 taagcgtgat gcgatgttgc gtttcaccaa accggtaacc ggcggctatt atttcgcacc
    73201 gtcgctggac aagttgatgg cgctgtaagc gtttctgatt cattgattaa aggccaggca
    73261 gtaacattac tgactggcct ttttattact tttgctttaa cgccgcatac acctgatcaa
    73321 ctacccaacc atacgttgca atcggcagct gaccgctttc gaacatattg ggattctttt
    73381 gcggatcggc aaccggcgaa tgtggcttgt tgcttaacat cacaatcgcc atatgattca
    73441 ccggatcgat aacggtcacc gttccggtcc agccagtgtg accgtaggtt tgcgggcttg
    73501 ccagcgtgcc aaacgtcggc gtcatggtgg cattaccatt cacgcgccag ccgaggccaa
    73561 aagtggcatc ttccttagag ctggtggtga acatcttcac cgtttccgca ctgaacagct
    73621 gcacatcgcc atagcccccg ccgttcagca tcgtttgcat taacaccgca atatcgccgg
    73681 tattggaaaa caaacctgcg tgcccggaaa cgccgcccat cgaataaaag gctttttcat
    73741 cgtgcacctg accccagagc gtggaggtgc ggatattcgg gaagtggatc actccatcgc
    73801 gggtattgcc gttcaattcc gtggcggcaa tttgttgcgg tttaaagcct ttcagcagcg
    73861 ggttaaatac cgtatgtgtc aggccgagcg ggcgataaat cgactcttca acatagcggt
    73921 caagcggctg accggtgacc gactcgacga taaatccaag cagcatataa tcgacatcac
    73981 tgtaaatatg cttgctgccg ggctgatact ctagcggcgt gcgcttgatc atctccagcg
    74041 tctggccttt atcctgggaa tataacgcgc ccgcgaccgc tttattcggg tattgtgggt
    74101 ccgccgggaa accgccgctg tgatgcagca ggtcagaaat ccgcagcgtg tttttgcctt
    74161 tgatggtgtc atttggacta tcggcaaacc ctggaatata cttcgcaatc agatcgtcag
    74221 gatgcagctt gccttcgctc attagctttt gcagagcaaa gttagtggcg tacatcttgg
    74281 tattggaagc caggtcatac agcgtcccgg tggtggcttt gacaggctgt tccatcaata
    74341 cgctgccatc gtactttttc gccgctcccc aggctttgcg atacacaatc tgattatctt
    74401 ttataatcag caggtttatg ccgggataac cggcgtccac ttgctggcta atccagcgat
    74461 ccatctggtt aagccgttcg acgttgaacc ctgctttctc tggcgaactt tctgtcagaa
    74521 cagggtattt tgcggcgctg acgctacaac taacagccag cagagaaaga tagagcattg
    74581 tccgtttcat aatatcagtc cagattgacg ttacggcagc caaaaagcgt ggtgaaaata
    74641 aacccgcaaa cccatgccac cagaatcccg ccagcgtaga ctgccatcgc cggaagaatg
    74701 ccttgtgctg aagtcatcag cggcagcgcc accagaccag acggcccaaa ggcgctgttt
    74761 aagcccatcg gcagacccca ccaggctatc aatccgataa acaaaccgcc cgccgcgccg
    74821 cctaaacagg cggtaataaa cggtttcatg cggggcaggg tgacgccata aatcaacggt
    74881 tcgccaacgc ccagcaggcc gggaataatc gccccgcgta cctgactgcg taatgcactg
    74941 tgcggttgcg cccgccagta gagtgctagc gccgcgccca cctggcctgc gcctgccatc
    75001 gaaaggatgg gaaataagct gttgaatccc tggctgtcca ttaacgcgag gtaaacagga
    75061 ataaagccct gatgcacgcc aaataccacg gcgatcagga acagcccggc taaaaccgca
    75121 caaccgagcg gattactgtt caggtgcata aacagccacg acataccttc gaataaccag
    75181 ccgcccagcg gcataatgat caggtaggcc agcgtagcgg tgatcagtag ggtgattaac
    75241 gaggtcagca gcatgtcgag atcgtcgggc ataaagcggc gcaccatgcc ttcgatgcgg
    75301 gcgcaggccc acgcggcaat caacacgccg ataatattgc cgcgcggatc gatgggcaga
    75361 ccaaagaaat cgtgaaaacc ggcgtagtaa ccggtggttg cagcggggtt ataaccgagc
    75421 aaaaagagtg cggcaataat tgcgccattg acgcccgtgc cgccaaatgc ctgggcggcg
    75481 ttatagccca ccagaatcac caggaaggtg aacaaacctt tgctgaacac cttcataaaa
    75541 ttcagcgcgt cgggtagcgt gccctgagca tctgccggaa cgtgcatcac cgtggcaatt
    75601 aacgtcgcta tccccagcag cagaccggcg gcaataaaac cggggataag cggcgtgaag
    75661 atggtggcga atttggcgag aaattgttgc acgccggagg tttgtttggc ttttaactga
    75721 cgtttgttct gggcggcgat ttctgcggca tcctgtaccg gtgcttctcc cagcagctcg
    75781 ctcatcgctt ttgcggcacg atgcgcttta ccaggcccaa aaacgacctg cacctggtcg
    75841 ctggtcaaaa tgacgccctt cacgccttcc agcgttttga tattgggatc aaccagtgaa
    75901 ctgtcatgta cacccagacg caggcgcgtc atacagttac cacaactggc gatatttccc
    75961 ggtccgccga cacgggtaag aatggtgttc agaagttcac tgctgatctc tttggccatg
    76021 ggttattcct tgtctaaaac ctgacgaata aagccgccgt gttgatccag gcgtttttta
    76081 gcttctgcgg catcgagatt tttcagcacc atcacaatgg ccgttttaca gttgcgctcg
    76141 caggcaatta acgccgcttc cgcttgttcg gcattacatc cggtggcgtt tttaacgata
    76201 ttgacctggc gcacatgcag tttttcgttg gtggcgacca catcgaccat caggttgccg
    76261 aacactttgc cggatttaat catcagcccg gtggagagca tattgagcac cagtttctgc
    76321 gccgtacccg ctttcatccg cgaagaaccg gtaaccactt cggcacctac aatcggtgta
    76381 atggcaaact ctgcggtggt tgaaacggcg ctccccggat tacaggaaat tcccactgtg
    76441 cggcagccga gctggcgtgc gtattccagt ccggcaatta catacggcgt gcgaccactg
    76501 gccgcaatgc caaccaccac atcctgcgcg gttaagccga tgtttttcag atcattaaca
    76561 ccgccttccc ggctatcttc agcgccttcc accgcgtgct gaatggcata ttcgcctcca
    76621 gcaatcaaac caaccaccag acccggttta acgccgtagg tgggcggaca ttcgctggca
    76681 tccagaatcc ccagacgacc ggatgttccc gcaccgagat aaatcagacg accgccgccg
    76741 cttacctggg cgtggataac atcgatcgcc gcggcgatat ccggcagtac gcgctcaacg
    76801 gcaagcggta cggttttatc ttcatcgttg ataatccggc acatttccag cgttgatacg
    76861 cggtcaattt cagccgaggc ggcgttcgag ccttcggtaa tcatcttttc aagttgcatc
    76921 ggtggtgacc ttactattta cgatcaaata attgcagatg tatggaatca tatatcccga
    76981 attgacagac ttaaaggaat cattgagtct acactcgcag agtgtgaaga gcgtcataag
    77041 aacttaagcg gaatttttgc tgccagccca ggagagtgga agatgttgta cctgacgaaa
    77101 atacgcaatg cggaaagtga atttaccgag aacgagcaaa aaattgctga ctttctgcgg
    77161 gccaacgtga gtgagctgaa atccgtctct tcgcgcaaga tggcgaaaca gctcggcatc
    77221 agccagtcga gtattgtgaa gtttgcccag aagctcggcg cacaaggatt tactgaattg
    77281 cgtatggcgt taataggcga atacagtgcc agccgggaga aaacgaatgc cacggcgctg
    77341 cacctgcaca gttcgattac cagtgatgat tcgctggaag tgattgcccg caaactgaat
    77401 cgcgaaaaag agctggcgct ggagcaaacc tgcgcgttgt tcgactacgc gcggctgcaa
    77461 aaaatcattg aggtcatcag taaagcaccg tttatccaga taacgggcct gggcggatcg
    77521 gcgctggtgg ggcgcgatct gtcgttcaaa ctgatgaaaa ttggatatcg cgtggcctgc
    77581 gaagccgaca cgcacgtaca agccaccgtt tcccaggcgt tgaaaaaagg cgatgtacaa
    77641 atcgctatct cttacagcgg cagtaaaaaa gagattgtct tgtgcgcaga agcggcacga
    77701 aagcaggggg caacggtgat tgccattact tctctggctg actctccgct gcggcggctg
    77761 gcgcatttca cgctcgatac cgtttccggt gaaaccgaat ggcgtagctc gtcgatgtct
    77821 acccgcacgg cgcaaaattc tgttaccgat ttactgtttg ttggtcttgt gcaactcaat
    77881 gatgtggagt cattgaaaat gattcagcgc agcagtgagc taacacaacg cctgaaatga
    77941 tgcataaagc agcgactgga ttgagatttt cctgaattag tgagctgatc cgcagcaata
    78001 ttttgtttat cctgtatttt cagagggaat ggagtgtaac gctctgtatt aacaaggaga
    78061 gcattaaaat gggtaaactc acgggcaaga cagcactgat tacgggcgca ttgcagggaa
    78121 ttggcgaagg aattgccaga acttttgcgc gtcatggcgc aaacctaatc ttgctggata
    78181 tctcccctga gatcgaaaag ctggcggacg aactgtgtgg tcgtggtcat cgctgtacgg
    78241 cggttgtcgc cgatgtgcgt gacccggcgt cggtagccgc agctatcaaa cgcgcgaagg
    78301 aaaaagaagg gcgcattgat atcctggtga ataacgcagg cgtttgtcgt ctgggcagtt
    78361 tcctcgatat gagcgatgac gatcgcgatt tccatattga catcaatatt aaaggcgtat
    78421 ggaacgtcac gaaggcggtg ctgccggaga tgattgcgcg caaagatggt cgcattgtga
    78481 tgatgtcttc ggtcactggc gatatggtgg ccgatccggg tgaaacggcg tacgccttaa
    78541 cgaaagcggc gattgttggc ctgactaaat cgctggcggt ggagtacgcg caatccggta
    78601 ttcgcgttaa cgccatctgc ccgggatacg tccgcacgcc aatggcggaa agcattgccc
    78661 gccagtcgaa cccggaagat ccagagtcgg tgctgactga tatggcaaaa gcaatcccgc
    78721 tgcgtcgcct cgccgatccg ctggaagtcg gcgaactggc ggccttcctc gcatcggatg
    78781 aatccagcta tttaaccggt acacagaatg tgattgatgg cggcagcaca ctgccggaga
    78841 cggtcagcgt cggtatctga ttcacctctg tttcctccct gcatgtgtgg ggaggatttc
    78901 gtcttattcc cttttcaact tccaaatcac caaacggtat ataaaaccgt tactcctttc
    78961 acgtccgtta taaatatgat ggctattaga aagtcattaa atttataagg gtgcgcaatg
    79021 gccgttaact tactgaaaaa gaactcactc gcgctggtcg cttctctgct gctggcgggc
    79081 catgtacagg caacggaact gctgaacagt tcttatgacg tctcccgcga gctgtttgcc
    79141 gccctgaacc cgccgtttga gcaacaatgg gccaaagata acggcggcga caaactgacg
    79201 ataaaacaat ctcatgccgg gtcatcaaaa caggcgctgg cgattttgca gggcttaaaa
    79261 gccgacgttg tcacttataa ccaggtgacc gacgtacaaa tcctgcatga caaaggcaag
    79321 ctgatcccgg cggactggca aacgcgcctg ccgaataata gctcgccgtt ctactccacc
    79381 atgggcttcc tggtgcgtaa gggtaacccg aagaatatcc acgactggaa cgacctggtg
    79441 cgctccgacg tgaagctgat ttttccgaac ccgaaaacgt ctggtaacgc gcgttacacc
    79501 taccttgcgg catggggcgc agcggacaaa gctgacggtg gcgacaaagc caaaaccgaa
    79561 cagtttatga ctcagttcct gaaaaacgtt gaagtgttcg ataccggcgg tcgtggcgcg
    79621 accaccacct tcgccgagcg cggtatgggc gatgtattga tcagcttcga gtcggaagtg
    79681 aacaacatcc gcaaacagta cgaagcgcag ggctttgaag tggtgattcc gaaaaccaac
    79741 attctggcgg aattcccggt ggcgtgggtc gataaaaacg tgcaggccaa cggtacggaa
    79801 aaagccgcaa aagcctacct gaactggctc tacagcccgc aggcgcagac catcatcacc
    79861 gactattact accgcgtaaa taacccggaa gtcatggaca aactgaaaga taaattcccg
    79921 cagaccgaac tgttccgtgt ggaagacaaa tttggctcct ggccggaagt gatgaaaacc
    79981 cacttcacca gcggcggcga gttagacaag ctgttagcgg cggggcgtaa ctgatgtttg
    80041 cagtttcatc aagacgcgtg ctgccgggct ttaccttaag cctcggcacc agtctgctgt
    80101 ttgtttgcct gattttgctc ctgccactct ccgcgctggt gatgcagctg gcccagatga
    80161 gctgggcgca gtactgggag gtgatcacca acccgcaagt ggtcgcagcc tataaagtga
    80221 cgctgctgtc ggcgtttgtg gcgtcgattt ttaacggcgt tttcggcctg ctgatggcgt
    80281 ggatcttaac tcgttatcgc ttccctggcc gcacgctgct tgatgcgctg atggatttac
    80341 cctttgcgct gccaacggca gtcgccggtt taacgctggc ctcgctcttt tccgtgaacg
    80401 gtttttacgg tgaatggctg gcgaagtttg atatcaaagt cacctacacc tggcttggga
    80461 ttgcggtggc gatggccttt accagcattc cgtttgtggt gcgtaccgtg cagccggtgc
    80521 tggaagagtt aggcccggaa tatgaagaag cggcggaaac gcttggtgca acgcgctggc
    80581 agagtttctg caaagtggtg ctgccggagc tttctccggc gctggtggcg ggcgtggcgt
    80641 tgtcgtttac ccgtagtctt ggtgagtttg gcgcggtgat atttatcgcc gggaacatcg
    80701 cctggaagac ggaagtgacg tcgctgatga ttttcgttcg cttacaggag tttgattacc
    80761 cggcggcgag cgcgattgct tcggtgatcc tcgcggcatc cctgatactg ctgttctcaa
    80821 ttaacactct gcaaagtcgc tttggtcggc gtgtggtagg tcattaatgg cggaagtgac
    80881 acaattgaag cgttatgacg cgcgcccgat taactggggc aaatggtttc tgattggcat
    80941 cgggatgctg gtatcggcgt tcatcctgct agtgccgatg atttatatct tcgtacaggc
    81001 gttcagcaaa gggctgatgc cggttttaca gaatctggcc gatccggata tgctgcacgc
    81061 catctggctg acggtgatga tcgcgctgat tgccgtaccg gtaaacctgg tgttcggcat
    81121 tctgctggcc tggctggtga cgcgctttaa cttccccgga cgccagttac tgctgacact
    81181 gctggatatt ccgtttgccg tatcgccggt ggttgccggt ctggtgtatc tgctgttcta
    81241 cggctccaac ggcccgctgg gtggctggct ggatgaacat aatctgcaaa ttatgttctc
    81301 ctggccgggg atggtgctgg tcaccatctt cgtgacgtgt ccgtttgtgg tgcgcgaact
    81361 ggtgccggtg atgttaagcc agggcagcca ggaagacgaa gcggcgattt tgcttggcgc
    81421 gtctggctgg cagatgttcc gccgcgtcac attgccgaac atccgctggg cgctgctgta
    81481 tggcgtagtg ctgaccaacg cccgcgcgat tggcgagttt ggcgcggtgt cggtggtttc
    81541 cggctcgatt cgtggcgaaa cactttcgct gccgttacag attgaattgc tggagcagga
    81601 ctacaacacc gtcggctcct ttaccgccgc cgcgctgttg acgctgatgg cgattatcac
    81661 cctgttttta aagagtatgt tgcagtggcg cctggaaaat caggaaaaac gcgcgcagca
    81721 ggaggaacat catgagcatt gagattgcca atattaagaa gtcgtttggt cgcacccagg
    81781 tgctgaacga tatctcactg gatattcctt ctggtcagat ggtcgcgttg ctggggccgt
    81841 ctggttccgg gaaaaccacg ctgctgcgca ttattgccgg gctggagcat caaaccagcg
    81901 ggcatattcg cttccacggc accgacgtca gccgtctgca cgcacgcgat cgcaaggtcg
    81961 gtttcgtgtt ccagcattac gcgctgttcc gccatatgac ggtattcgac aatatcgctt
    82021 ttggcctgac ggtgctgccg cgtcgcgagc gcccgaatgc cgcggcgatc aaagcgaaag
    82081 tgacaaaatt gctggagatg gtgcagcttg ctcatctggc ggatcgttat ccggcgcagc
    82141 tttccggcgg ccagaaacag cgtgtggcgc tggcgcgtgc gctggctgtg gaaccgcaaa
    82201 ttctgctgct tgatgaaccg tttggcgcgc tggatgcgca ggtgcgtaaa gagctgcgtc
    82261 gctggctgcg tcaactccat gaagaactaa aattcaccag cgtttttgtg acccacgatc
    82321 aggaagaagc gaccgaagta gctgatcgtg tagtggtgat gagccagggc aatattgaac
    82381 aggctgacgc gccggatcag gtatggcgcg aaccggcgac ccgttttgtg ctcgaattta
    82441 tgggcgaagt gaaccgcctg cagggaacca ttcgcggcgg gcagttccat gttggcgcgc
    82501 atcgctggcc gctgggctac acacctgcgt atcaggggcc ggtggatctc ttcctgcgcc
    82561 cttgggaagt ggatatcagc cgccgtacca gcctcgattc gccgctgccg gtacaggtac
    82621 tggaagccag cccgaaaggt cactacaccc aattagtggt gcagccgctg gggtggtaca
    82681 acgaaccgct gacggtcgtg atgcatggcg acgatgcccc gcagcgtggc gagcgtttat
    82741 tcgttggtct gcaacatgcg cggctgtata acggcgacga gcgtattgaa acccgcgatg
    82801 aggaacttgc tctcgcacaa agcgcctgat aggttgagtg aatgttaacg cccggaggcg
    82861 cttcccgcga tccgggcttt ttaatggtgt aggcctgata agacgcgcaa gcgtcgcatc
    82921 aggcaacacc acgtatggat agagatcgtg agtacattag aacaaacaat aggcaatacg
    82981 cctctggtga agttgcagcg aatggggccg aataacggca gtgaagtgtg gttaaaactg
    83041 gaaggcaata acccggcagg ttcggtaaaa gatcgtgcgg cgctttcgat gatcgtcgag
    83101 gcggaaaagc gcggggaaat taaaccgggt gatgtgttaa tcgaagccac cagtggtaac
    83161 accggcattg cgctggcaat gattgccgcg cttaaaggct atcgcatgaa attgctgatg
    83221 cccgacaaca tgagccagga acgccgtgcg gcgatgcgtg cttatggtgc ggaactgatt
    83281 cttgtcacca aagagcaggg catggaaggt gcgcgcgatt tggcgctgga gatggcgaat
    83341 cgtggtgaag gaaagctgct cgatcagttc aataatcccg ataaccctta cgcccattac
    83401 accactaccg ggccggaaat ctggcagcag actggcgggc gcattaccca ttttgtctcc
    83461 agcatgggaa caaccggcac tatcaccggc gtttcacgct ttatgcgcga acaatccaaa
    83521 ccggtgacca ttgttggcct gcagccggaa gagggcagca gcattcccgg cattcgccgc
    83581 tggcctacgg aatatctgcc ggggattttc aacgcttctc tggtggatga ggtgctggat
    83641 attcatcagc gcgatgcgga aaacaccatg cgcgaactgg cggtgcggga aggaatattc
    83701 tgtggcgtca gctccggcgg cgcggttgcc ggagcactgc gggtggcaaa agctaaccct
    83761 ggtgcggtgg tggtagcgat catctgcgat cgtggcgatc gctacctttc caccggggtg
    83821 tttggggaag agcattttag tcagggggcg gggatttaag attattgcgc aggcactgtt
    83881 ttatccgtct gcgcaattaa cgcatgtaaa aaaggctgtg cgttctcatc gctcttaccg
    83941 gggatcttca caatatacgg cttcccggta atcgatgacg acgaagcaac cttatcaata
    84001 aactgctcgg cagtgtcaat gcggttacgg gtattgccca gcttcagacg cagatgagaa
    84061 accgcttcat cgcaggtatg ttcatcaccg ttgcgcacaa atatcaaatc ctttttctgt
    84121 gctaatccct ccagcatggc gttgatgcgg gcttcttcat gggcagttaa cttcgcgtaa
    84181 gcggggagtg tcattagtag tgtaatgacc agacaaatga ttttcttcac tgaattacct
    84241 tatccttgtt ttgtaatagc cgatttgact gccagaatca ggtaaagttt cggttggaat
    84301 acgatgagga tcatcggcaa ggagaaaaaa ttaaatgagt agtttgttgt tgtttaacga
    84361 taagagcagg gcactgcagg cggatatcgt cgccgtgcag tcgcaggtag tgtacggcag
    84421 cgtaggcaac agcattgccg tgcctgctat caaacagaac ggcctgaatg tctttgccgt
    84481 gccgacggta ttgctgagca atacgccgca ttatgacact ttctacggtg gtgcgattcc
    84541 ggacgaatgg tttagcggct atttgcgtgc gcttcaggag cgtgatgcgc tgcgccaact
    84601 tcgagctgta accacgggct atatgggaac ggcatcgcaa atcaaaatcc ttgccgagtg
    84661 gctgactgcg ctacgcaaag accatcctga cctattgatc atggtcgatc cggtgattgg
    84721 cgatattgat agcggaattt atgtcaaacc tgaccttccc gaggcgtatc gacaatattt
    84781 actgccgctg gcgcagggaa ttacccccaa tatctttgag ctggaaatcc tgaccggtaa
    84841 aaattgccgc gatctcgaca gtgccattgc tgccgcaaaa agtctgcttt cagacacact
    84901 aaaatgggtg gtgattacca gcgcctccgg taatgaagaa aatcaggaga tgcaggttgt
    84961 ggtggtcact gccgacagcg tgaatgtcat ttcccattca agggtaaaaa ccgacctgaa
    85021 agggactggc gacctgtttt gtgctcagct tatcagtggt ttgctgaaag ggaaggcatt
    85081 aaacgatgcg gtgcaccgcg cggggttgcg cgtactggaa gtgatgcgct acacccagca
    85141 gcatgagagc gatgaattga ttttgccgcc gctggcggaa gcataaaaaa atggcgccga
    85201 tgagcgccat ttttcactgc ggcaagaatt acttcttgat gcggataacc ggggtttcac
    85261 ccacagtcac gctaccggac agtttgatca gttctttgat ttcgtccatg ttggagataa
    85321 caaccggagt cagggtagac ttggctttct cttccagcag cggcagatca aattcaatga
    85381 cagtatcgcc aactttcacg cgctgacctt cttcagcaat acgcttgaag ccttcgcctt
    85441 tcagttcaac ggtgtcgata ccgaagtgga cgaacagttc aacgccgcta tcagattcga
    85501 tagagaatgc gtggttggtt tcaaagattt taccaatggt gccgtctaca ggcgcgacca
    85561 ttttgttacc cgttggtttg atagcaatac catcaccaac gattttttcc gcaaaaacga
    85621 catccggcac gtcttcgata ttgacgatct cgccagagag cggagcaatg atctcaatag
    85681 ttccggtatc cttcttgtcg tcggaaacca gagatttcag tttatcgaac aaacccatga
    85741 tcttctccta agcagtaaat tgggccgcat ctcgtggatt agcagattgt tttttcttca
    85801 atgaacttgt taaccagcgt cattaactcg tccgttgtcg gttgagcaag agcctgctct
    85861 gctaacacct tcgcatcttc gaagttcgtg ttacggataa tcttcttaat gcgcgggata
    85921 gaaatggcgc tcatagagaa ttcgtccaga cccatcccca gcaacagaag tgtagcacgt
    85981 tcatcgccag caagctcacc acacatgcca gtccatttgc cttcagcatg agaagcatca
    86041 ataacttgct tgatcaagtt cagcacggac ggtgacattg gctggtaaag gtgtgaaatc
    86101 atatcattac cacggtcaac tgccagagtg tactgcgtta aatcattggt gccgatacta
    86161 aagaaatcaa cttctttggc taaatgacgt gcaattgttg cggcagccgg tgtttccacc
    86221 attacgccga tttcaattga ctcgtcaaac gctttacctt cgtcgcgcag ttcctgtttg
    86281 tagatttcga tctctttgcg cagtgcacgc acttcttcaa cagagatgat catcgggaac
    86341 ataatgcgca atttaccgaa agccgaggca cgcaggatag cgcggagctg atcgcgcagg
    86401 atctctttac gatccatcgc gatacggata gcgcgccagc cgaggaacgg gttctcttct
    86461 ttcgggaagt tcatgtatgg cagctctttg tcgccgccga tgtccatggt acgaacgata
    86521 accgcctgcg agccacacgc ttcagccact gctttgtaag cagcaaactg ttcttcttca
    86581 gtgggcagcg cgtcgcggtc catgaacagg aactcagtac gatacagacc aacgccttca
    86641 gcgccgttac gctctgcacc ttcaacgtca cgaaccgtac caatgttagc gcatacttct
    86701 acctggtgac cgtccagcgt aatagctggc agatctttca gtttagcaag ctctgctttt
    86761 tcagaagcca cttgctcctg aacagcgcgc attttatcaa taacttcgtt ggttggattg
    86821 acgtaaacct gattatttac ggcatccaga atcagatagt cgtcattttt cacctgagag
    86881 gtgacgctac cggtacccac gatagcaggc agttccagag aacgcgccat gatagaggtg
    86941 tgggaagtac ggccacccgc gtcggtgatg aaacccagca ccttcttcag gttcagctgt
    87001 gcggtttcgg acggcgtcag gtcagcggca accagaatga cttcatcctg aatggcgctc
    87061 aggtcgataa tcttcaggcc caggatgttg cgcagcaggc gcttaccgat atcacgtacg
    87121 tcagccgcac gttctttcag gtattcatca tccagctctt ccagggcaga agcctgacct
    87181 tcgataactt catgagcagc tgcgtcagct gtcatgtgtt tatctttaat cagggctatg
    87241 atttcctgct ccagctcctc atcttcgagc agcataatat gcccttcaaa gatggcttct
    87301 ttttcttcac cgaacgtttc accagctttc gttttgatcg tttccagctg ggctgatgcc
    87361 ttggcacgac cgctcagaaa acgttcaact tcctgatcaa cctggtcggc agaaattttt
    87421 ttccggtcaa tgacaatttc gtcttctttc agaagcagag ctttaccgaa agcgataccc
    87481 ggggatgcta aaatgcctga aatcataacc ctaccttact tgtgactgat ttttaaaaga
    87541 acccgggaaa ttactcgagt tccgccatca gtttaaccag atgttcaacc gctttctgct
    87601 cgtcttcgcc ttctgcggag atagtcacaa cggtaccttg agtcaggccc agagtctgca
    87661 gtttaaacag gcttttcgcg ctggcgcttt tgccgttgga agtcacagta atttcagaag
    87721 tgaagccctt agcttctttt acaaactggg cagcagggcg ggtgtgcaga ccgttcggag
    87781 cggtaatggt aacttcttgc tggaacattg tatttcccca acttataggt ttagtgttgt
    87841 ggaactaaag tctagcctgg cggttcgact ttagcctgta ttgttagcgc cagtttttaa
    87901 cagacgcgac gcacgaagag cgcaatacag tccattgctg gcgggtgttg accgctgacg
    87961 tttcgtacgt cattaaacat tatgccgcta aaggaagaat tgaaccaaat cataaaatcg
    88021 attcagcttt ggcttttcct gtaacgatta atttcgcgca tcaaaataat tagtctggtt
    88081 aaataccagt tccgacaggc tgaatcaatg ccaggagggg cgaaagtttg aagcaggcca
    88141 caaaaaagca cctgaaaagg tgctttttta cgcattttta acaagctggc attactgttg
    88201 caattctttc tcagtgaaga gatcggcaaa caatgcggtg cttaaataac gctcacccga
    88261 tgatggtaga ataaccacaa tattcttgtt ggtaaagctt tcatcttctt gtagtttcaa
    88321 cgccgcggca acagctgctc cagaagagat acctgcaaga ataccttctt cttccattag
    88381 acgacgggcg gtagaaatgg cttcttcatt ggtgatgcca atgactttat cgaccagctt
    88441 gagatcgagg ttagccggga taaaaccagc gccaataccc tgaattttat gcgggccagg
    88501 tttaatctct tcacctgcca gcgcctgggc gataactgga gaatcggttg gctcaacggc
    88561 gacagagata agatcggtct tgcctttggt gcctttaatg tagcggctga cgccagtcag
    88621 cgtaccgcca gtcccaacgc cagcaataaa tacatcaacc tgaccgtcgg tatcttccca
    88681 gatctccgga ccggtggttt tttcgtgaat ttcagggttt gccggattgc tgaattgttg
    88741 cagcagcagg tatttctctg gattgctggc gacaatttct tctgcttttt ggattgcgcc
    88801 tttcatgcct ttagcacctt cggtcagcac caggtttgca cctaacgctt tcagcagctt
    88861 gcggcgttca atactcatgg tttctggcat ggtcagggtg agtttgtaac cgcgagcggc
    88921 agctacatag gccagtgcaa tcccagtatt accgctggtt ggttcaacca gttcaacgcc
    88981 tggtttcagc acgccgcgct tttcggcatc ccaaatcatg ttggcaccga tacggcactt
    89041 aacgctgaag ctggggttac gagattccac cttcgccaga atgcgtccgt taccgatgcg
    89101 attcaggcga accagcggcg tgtgaccgat agtcagcgag ttatcttcaa aaatcttact
    89161 catggcctgt ccttaactgt atgaaattgg gatacaacag gtagcatacc cgctcagaga
    89221 atatgcggaa gtaaggattt agcatatcta tatacagaag ggaaataatg acatgcaaga
    89281 tggaataagg ggcggcataa gccccccctg tttcacacaa acggtttaca aaataaccgg
    89341 tagattgtta ccgccacatc gcgtgtttat cgcgatagca atcgacccac atcgccgtcg
    89401 cgccacaaac ggcaacgggc ataatgaaca gattaagcag cgggatcatc gtaaacaggc
    89461 tggttaaagc accaaactgc atattggtga ttttgcgtgt gcgcagggcg gtgcgcatct
    89521 ctttaaacgg cactttgtgg ttatcgaagg ggtaatcgca atactggatg gctaacatcc
    89581 aggcgctaaa caggaaccac agtaccggcg cgacggtttg cccaatacca gggatgaagt
    89641 aaagaattag taatacaatt gcgcgcggca gataccaggc aaatttttgc cattcgcgtt
    89701 tcatgattcg cggcacatct ttcatgatac cgaaaatccc ggtatctggc ggtgtagcgc
    89761 cagtcaatcg tgcttccagt tgttcagcca ataaaccgtt aaacggagcg gcaatccagt
    89821 tagcaatcgt ggagaagaaa tagccaaaca ctaacagcac agagatgaca gccagaggcc
    89881 acaacagata gctcagccat tgtaaccagt ccggaacata actcatgaga gtcgggatcc
    89941 agacatcgag ttgcgtaaag agccaccaga atgcgccccc catcaacaaa atattgacca
    90001 gcagcggtaa aataacgaaa cgccgaatcc caggttgcga gacgagcttc cagccttgcg
    90061 caaaatagta aaaaccgctg cgtggggcag atgtgaatga tgaaaccata atcaggatga
    90121 gctccttttg accaatccca ggaaaattgt gcgtatttta ccgggtaatt gcgcaatgga
    90181 cagttaggat atgttcgaaa aaacagcaaa aagcacgatt tcatctatct ttgtgctgtg
    90241 aaagttaata gtgcacttgc acttgaggta atcggcaaat actcttagtg agtaaatgtt
    90301 tgccgtggtg gcaaggtgtt agaacaacag agaatataat gatgcaggat ttgcgtctga
    90361 tattaatcat tgttggcgcg atcgccataa tcgctttact ggtacatggt ttctggacca
    90421 gccgtaaaga acgatcttct atgttccgcg atcggccatt aaaacgaatg aagtcaaaac
    90481 gtgacgacga ttcttatgac gaggatgtcg aagatgatga gggcgttggt gaggttcgtg
    90541 ttcaccgcgt gaatcatgcc ccggctaacg cccaggagca tgaggctgct cgtccgtcgc
    90601 cgcaacacca gtaccaaccg ccttatgcgt ctgcgcagcc gcgtcaaccg gtccagcagc
    90661 cgcctgaagc gcaggtaccg ccgcaacatg ctccgcgtcc agcgcagccg gtgcagcaac
    90721 ccgtgcagca gcctgcctat cagccgcagc ctgaacagcc gttgcagcag ccagtttcgc
    90781 cacaggtcgc gccagcgccg cagccagtgc attcagcacc gcaaccggca caacaggctt
    90841 tccagcctgc agaacccgta gcggcaccac agcctgagcc tgtagcggaa ccggctccag
    90901 ttatggataa accgaagcgc aaagaagcgg tgattatcat gaacgtcgcg gcgcatcacg
    90961 gtagcgagct aaacggtgaa ctgcttctta acagcattca acaagcgggc ttcatttttg
    91021 gcgatatgaa tatttaccat cgtcatctta gcccggatgg cagcggcccg gcgttattca
    91081 gcctggcgaa tatggtgaaa ccgggaacct ttgatcctga aatgaaggat ttcactactc
    91141 cgggtgtcac tatctttatg caggtaccgt cttacggtga cgagctgcag aacttcaagc
    91201 tgatgctgca atctgcgcag catattgccg atgaagtggg cggtgtcgtg cttgacgatc
    91261 agcgccgtat gatgactccg cagaaattgc gtgagtacca ggacatcatc cgcgaagtca
    91321 aagacgccaa cgcctgatac acttaaggca aattaactcc tcttcgaacc cccgcttgtc
    91381 gggggttttt agcattgatg gtgcgatatg gaatcaatcg aacaacaact gacagaactg
    91441 cgaacgacgc ttcgccatca tgaatatctt tatcatgtga tggatgcgcc ggaaattccc
    91501 gacgctgaat acgacaggct gatgcgcgaa ctgcgcgagc tggaaaccaa acatccagaa
    91561 ctgattacgc ctgattcgcc tacccaacgt gtaggtgctg cgccgctggc ggctttcagc
    91621 cagattcgcc atgaagtgcc aatgctgtcg ctggataacg tttttgatga agaaagcttt
    91681 cttgccttca acaaacgagt gcaggaccgt ctgaaaagca acgagaaagt cacctggtgc
    91741 tgtgagctga agctggatgg ccttgctgtc agtattctgt atgaaaatgg cgttttagtc
    91801 agtgccgcga cccgtggcga tggcaccacc ggggaagata tcacgtctaa cgtgcgtacc
    91861 attcgcgcca ttccactgaa gctgcacgga gagaatatcc cggcgcgtct ggaagtgcgt
    91921 ggtgaagtgt tcctgccgca ggcggggttc gaaaagatta acgaagatgc gcgacgcacg
    91981 ggcgggaaag tttttgctaa cccacgtaat gcggcagctg gttcactgcg tcagcttgat
    92041 ccgcgtatta cagcgaagcg accgctcact tttttctgct atggcgttgg tgttctggaa
    92101 ggtggcgagc tgccggatac tcatcttggc cgtttactgc aatttaaaaa gtgggggttg
    92161 ccggtcagcg atcgggtaac gctttgtgaa tcggcggaag aagtgctggc gttctatcac
    92221 aaagtggaag aagaccgccc gacgctgggc tttgatatcg acggcgtggt gattaaggtc
    92281 aactcactgg aacagcagga gcagcttggc tttgtcgcgc gagccccgcg ctgggcggta
    92341 gcgtttaaat tcccggcgca ggaacagatg acctttgtgc gtgacgtcga gtttcaggtt
    92401 gggcgtactg gcgcgattac gcctgttgcg cgtctggaac ctgtccatgt tgcaggcgtg
    92461 ctggtgagta acgcaacctt acacaatgcg gatgaaatcg aacgtcttgg tttacgcatt
    92521 ggcgataaag tggtgattcg ccgcgctggc gacgtgatcc cgcaggtggt gaacgtcgtg
    92581 ctttctgaac gcccggaaga tactcgtgag gttgtattcc cgacgcattg tccggtatgt
    92641 ggttctgacg ttgagcgtgt ggaaggtgaa gcggttgccc gctgtaccgg tggcctgatt
    92701 tgcggtgcgc agcgtaaaga gtcgctgaaa cactttgttt cccgccgtgc gatggatgtt
    92761 gacggaatgg gcgacaaaat catcgatcag ctggttgaaa aagaatatgt ccacactccg
    92821 gcggatctgt tcaaactcac cgcaggcaaa cttaccggac tggagcgtat ggggccaaaa
    92881 tcggcacaaa acgtggttaa cgcgctggaa aaagcgaaag aaaccacctt tgctcgcttc
    92941 ctctatgcac ttggcatccg tgaagtcggc gaggccaccg cagcaggtct ggcggcatat
    93001 ttcggcacgc tggaagcgct ggaagccgct tcgattgaag agctgcaaaa ggtgcctgat
    93061 gttggcattg tcgttgcatc ccacgttcac aacttctttg ccgaagaaag caaccgcaat
    93121 gtcatcagcg agctgttggc ggaaggtgtt cactggcctg cgccgatcgt tatcaacgcg
    93181 gaagagattg acagcccgtt tgctggtaaa accgtggtgc ttacgggcag cttaagccag
    93241 atgtcgcgtg atgacgctaa agctcgactg gtcgaactgg gcgcgaaagt cgcgggcagc
    93301 gtgtcgaaga aaaccgatct ggtgatagcg ggtgaagctg caggatctaa actggcgaag
    93361 gcgcaggaac tgggcattga agtcatcgac gaagcggaaa tgctgcgttt gctgggtagc
    93421 tgagatggaa aaagagcagc tgattgaaat agccaatacg ataatgccgt ttggcaaata
    93481 caaagggcgt cgcttaatcg acctgccgga ggagtatctg ctgtggtttg cccgcaaaga
    93541 tgagttcccg gcagggaagc tcggtgagct aatgcaaatc acgctgctga ttaaaaccga
    93601 ggggctgacg caactggtcc agcccctgaa gcgtccgctt taagctttat cggtgctgct
    93661 ttcctgctgc gcctgtaact gttcggtctg gcgtttgtat cgacgcgcca gcaccgcaca
    93721 gaccatcaat tggatctgat ggaaaatcat caggggcagc accatcatac cgatcaccga
    93781 tgtggggaac agaatgtttg ccatcgggat gccatttgcc agactctttt tcgaaccaca
    93841 aaagacgata gtaatttcat ctgccttatt gaagcccagt cggcgtgcca taaagacgtt
    93901 aactacaatc acgatagcca gaagaacgca gctgaccacc acgataaaca gcaatgatcc
    93961 ccagccaact ttatgccaga taccattaac gacggcttcg ctgaacgctg tataaaccac
    94021 caacagaatg gacgtctggt cagttttcgc aatccatttt ttattgcgcg acacccagtc
    94081 tccaatccac ggccgggaaa gatgccccaa cacaaacggc agcagcagtt gcagcataat
    94141 tttaccgacc tgctcaaggc tgccccctgc accgtgaaca ttcatcacca gaccaaccag
    94201 caatggtgaa aggaaaatcc ccagcaggct ggatgctgac gcagaacaaa ccgccgccgc
    94261 gacgttaccg cccgccattg acgtgaaggc gattgcagac tgcacggtag ccgggagaat
    94321 gcacaagtag agaaaaccgg agtagagcat cgggtcgaca tttaccggtt tccaccaggc
    94381 aaacagtaca cccagaatcg gaaacagcac gaaggtgctg cacattaccc acaaatgcag
    94441 tcgccagtga ccaccgccag caataatcgc ctcacgcgac aacttcgcgc cgtgcataaa
    94501 gaacagcagg gcaatagctg cggtggtcag attttcaaag aaggggacga aatcgcctct
    94561 ggccggaaag aaagaggcca gcaacaccac cgtgatcagg gttaaggtga aaggatcgag
    94621 gatacgaaaa agtttcataa agactccaga tgatcgatgg ttctattgtg cttcttccag
    94681 tttgagaaat aaaattgatt tattgcatcc attcatgaag aaaacagatg aattattctt
    94741 taaaacaatt aaaggttttc gtcacagtag cgcaggagaa aagttttagt cgtgcaggag
    94801 agcgtatcgg cctgagccag tcggcagtga gtcacagtgt gaaggagctg gaaaatcata
    94861 ctggtgttcg cctgctggac agaaccacgc gtgaagtggt gcttacagat gcagggcagc
    94921 agttggcttt gcgtcttgag cgactgctgg atgaacttaa cagcacgttg cgcgataccg
    94981 ggcgtatggg gcaacaactg agcggaaaag ttcgggtcgc tgccagccag accatttccg
    95041 cgcatcttat tccgcaatgc attgctgaaa gccatcgccg ctatccagat attcagtttg
    95101 tcctgcacga tcgtccgcag cagtgggtga tggaaagtat tcgccaggga gatgtcgact
    95161 ttggcatcgt catcgatcca ggcccagtgg gcgatctgca atgtgaagcg attctttccg
    95221 agcctttctt tctgctttgc catcgcgata gcgctttggc cgtggaagat tatgtaccct
    95281 ggcaggcatt acagggagcg aaattggtgt tgcaggatta cgcgtcaggc agccgaccgc
    95341 tgattgacgc agcgctggcg cgcaatggta ttcaggcgaa tattgtgcag gagattggac
    95401 atccggcgac gctgttcccg atggtagccg caggcatcgg catcagtatt cttcccgcac
    95461 tggcgctacc attgcctgaa ggtagcccgc tggtggtaaa gcgcattacg ccggttgttg
    95521 aacgccagtt gatgctggtg cgcaggaaga accgttcact ttccaccgcc gctgaagcgt
    95581 tatgggacgt ggtacgagac cagggcaatg cgctaatggc tggtcgggaa ggggatccgt
    95641 tgtatcagat atagatatcg atatgagtcg tattttcaac aggatttaga agggatacat
    95701 tcagagacaa acgctgctct ttctcctgcg ccttttctgc ctgctgtctc tgcaactgcg
    95761 ccagttgtgt ttccagtagg gtgatttgct gttgaatcaa ttcggcctgt ttttgcttgt
    95821 cttcagcact gccgctagtg tctacaatct ctttaatttg ttgagtgagt ttgatgattt
    95881 gctgacttat ccgcgcgatt tgtgaagcaa catcgctacc ttgtgatgcc ctgttactac
    95941 tctgtgtttg tatggaagga attgaagttg aagagatagt ggccattgtt cagtcctcgt
    96001 cactttacga ggtaatatcg gtagaagaac aaggaacttg agaagaaaaa tcaatcttac
    96061 aaatcgca
//
LOCUS       DAPGUL010000004        95764 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.004, whole genome shotgun sequence.
ACCESSION   DAPGUL010000004 DAPGUL010000000
VERSION     DAPGUL010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 95764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 95764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..95764
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.004"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            95..613
                     /locus_tag="RHX21_000274"
     CDS             95..613
                     /locus_tag="RHX21_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HDV1985516.1"
                     /translation="MMKFKKCLLPVAMLASFTLAGCQSNADDHAADVYQTDQLNTKQE
                     TKTVNIISILPAKVAVDNSQNKRNAQAFGALIGAVAGGVIGHNVGSGSNSGTTAGAVG
                     GGAVGAAVGSMVNDKTLVEGVSLTYKEGTKVYTSTQVGKECQFTTGLAVVITTTYNET
                     RIQPNTKCPEKS"
     gene            629..1168
                     /locus_tag="RHX21_000275"
     CDS             629..1168
                     /locus_tag="RHX21_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5384 family protein"
                     /protein_id="HDV1985517.1"
                     /translation="MKKVFLCAILASLSYPAIASSLQDQLSAVAEAEQQGKNEEQRQH
                     DEWVAERNREIQQEKQRRANAQAAANKRAATAAANKKARQDKLDAEATADKKRDQSYE
                     DELRSLEIQKQKLALAKEEARVKRENEFIDQELKHKAAQTDVVQSEADANRNMTEGGR
                     DLMKSVGKAEENKSESWFN"
     gene            complement(1261..2838)
                     /gene="guaA"
                     /locus_tag="RHX21_000276"
     CDS             complement(1261..2838)
                     /gene="guaA"
                     /locus_tag="RHX21_000276"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDV1985518.1"
                     /translation="MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEA
                     QIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEA
                     SNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFVTVAST
                     ESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAV
                     ARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDM
                     FGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQ
                     GTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELG
                     LPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTV
                     FLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGIS
                     RVVYDISGKPPATIEWE"
     gene            complement(2907..4373)
                     /gene="guaB"
                     /locus_tag="RHX21_000277"
     CDS             complement(2907..4373)
                     /gene="guaB"
                     /locus_tag="RHX21_000277"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004151980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HDV1985519.1"
                     /translation="MLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPM
                     LSAAMDTVTEARLAIALAQEGGIGFIHKNMSIERQAEEVRRVKKHESGVVTDPQTVLP
                     TTTLREVKELTERNGFAGYPVVTEENELVGIITGRDVRFVTDLNQPVSVYMTPKERLV
                     TVREGEAREVVLAKMHEKRVEKALVVDDEFHLIGMITVKDFQKAERKPNACKDEQGRL
                     RVGAAVGAGAGNEERVDALVAAGVDVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGG
                     NVATAAGARALAEAGCSAVKVGIGPGSICTTRIVTGVGVPQITAVADAVEALEGTGIP
                     VIADGGIRFSGDIAKAIAAGASAVMVGSMLAGTEESPGEIELYQGRSYKSYRGMGSLG
                     AMSKGSSDRYFQSDNAADKLVPEGIEGRVAYKGRLKEIIHQQMGGLRSCMGLTGCGTI
                     DELRTKAEFVRISGAGIQESHVHDVTITKESPNYRLGS"
     gene            4535..5905
                     /gene="xseA"
                     /locus_tag="RHX21_000278"
     CDS             4535..5905
                     /gene="xseA"
                     /locus_tag="RHX21_000278"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HDV1985520.1"
                     /translation="MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPAS
                     GHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESM
                     QPAGEGLLQQKYEQLKAKLQAEGLFDQQYKKPLPSPAHCVGVITSKTGAALHDILHVL
                     KRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANQRNECDVLIVGRGGGSLEDLWSFND
                     ERVARAIFASRIPVVSAVGHETDVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQS
                     TRQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLERLQKRMSFALENQL
                     KRTGQQQQRLTQRLNQQNPQPKIHRAQTRIQQLEYRLAETLRVQLSATRERFGNAVTH
                     LEAVSPLSTLARGYSVTTATDGNVLKKVKQVKAGEMLTTRLEDGWIESEVKNIQPVKK
                     SRKKVH"
     gene            complement(5902..6117)
                     /locus_tag="RHX21_000279"
     CDS             complement(5902..6117)
                     /locus_tag="RHX21_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417005.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HDV1985521.1"
                     /translation="MELHCPQCQHVLDQDNGHARCPSCGEIIEMKALCPDCHQPLQVL
                     KACGAVDYFCQHGHGLISKKRVEFVLA"
     gene            complement(6186..7658)
                     /gene="der"
                     /locus_tag="RHX21_000280"
     CDS             complement(6186..7658)
                     /gene="der"
                     /locus_tag="RHX21_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417006.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HDV1985522.1"
                     /translation="MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGR
                     AEIEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAI
                     AKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLL
                     PWMEDLAPQEEVDEDAEYWAQFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTL
                     TNRILGEERVVVYDMPGTTRDSIYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVI
                     KTLQAIEDANVVMLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQV
                     KETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAV
                     EDHQPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMG
                     SPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKNK"
     gene            complement(7776..8954)
                     /gene="bamB"
                     /locus_tag="RHX21_000281"
     CDS             complement(7776..8954)
                     /gene="bamB"
                     /locus_tag="RHX21_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamB"
                     /protein_id="HDV1985523.1"
                     /translation="MQLRKLLLPGLLSVTLLSGCSLFNSEEDVVKMSPLPTVENQFTP
                     TTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGLVKALNADDGKEIWSVSLAEKDG
                     WFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSDGTVAWQTKVAGEALSRPVVSDG
                     LVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGESAPATAFGAAVVGGDNGRVSA
                     VLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQ
                     IMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWAQSDLLHRLLTSPVLYN
                     GNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGKLLIQAKDGTVYSITR
                     "
     gene            complement(8965..9585)
                     /gene="yfgM"
                     /locus_tag="RHX21_000282"
     CDS             complement(8965..9585)
                     /gene="yfgM"
                     /locus_tag="RHX21_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ancillary SecYEG translocon subunit YfgM"
                     /protein_id="HDV1985524.1"
                     /translation="MEIYENENDQVEAVKRFFAENGKALAVGVILGVGALIGWRYWNS
                     HQVDSARSASLAYQNAVTAVSEGKPDSIPAAEKFAAENKNTYGALASLELAQQFVDKN
                     ELEKAAAQLQQGLADTSDENLKAVINLRLARVQVQLKQADAALKTLDTIKGEGWAAIV
                     ADLRGEALLSKGDKQGARSAWEAGVKSDVTPALSEMMQMKINNLSI"
     gene            complement(9603..10877)
                     /gene="hisS"
                     /locus_tag="RHX21_000283"
     CDS             complement(9603..10877)
                     /gene="hisS"
                     /locus_tag="RHX21_000283"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HDV1985525.1"
                     /translation="MAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLP
                     IVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQE
                     QRLWYIGPMFRHERPQKGRYRQFHQLGCEVFGLQGPDIDAELIMLTARWWRALGISEH
                     VTLELNSIGSLEARANYRDALVAFLEQYKDKLDEDCKRRMYTNPLRVLDSKNPEVQAL
                     LNDAPALGDYLDEESREHFAGLCKLLESAGIAYTVNQRLVRGLDYYNRTVFEWVTNSL
                     GSQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFKADPVVDIYLV
                     ASGADTQSAAMALAERLRDELPGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEV
                     ANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG"
     gene            complement(10988..12106)
                     /gene="ispG"
                     /locus_tag="RHX21_000284"
                     /gene_synonym="gcpE"
     CDS             complement(10988..12106)
                     /gene="ispG"
                     /locus_tag="RHX21_000284"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HDV1985526.1"
                     /translation="MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEAT
                     VNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGV
                     DCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLES
                     AMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAV
                     KSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQ
                     EFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGV
                     RKDRLDNNDMIDQLEARIRAKASQLDEARRIDVQQVEK"
     gene            complement(12133..13146)
                     /gene="rodZ"
                     /locus_tag="RHX21_000285"
     CDS             complement(12133..13146)
                     /gene="rodZ"
                     /locus_tag="RHX21_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HDV1985527.1"
                     /translation="MNTEATHDQNEALTTGARLRNAREQLGLSQQAVAERLCLKVSTV
                     RDIEEDKAPADLASTFLRGYIRSYARLVHIPEEELLPGLEKQAPLRAAKVAPMQSFSL
                     GKRRKKRDGWLMTFTWLVLFVVIGLSGAWWWQDHKAQQEEITTMADQSSAELSSNSEQ
                     GQSVPLNTSTTTDPATTSTPPASVDTTATNTQTPAVTAPAPAVDPQQNAVVSPSQANV
                     DTAATPAPTATTTPDGAAPLPTDQAGVTTPAADPNALVMNFTADCWLEVTDATGKKLF
                     SGMQRKDGNLNLTGQAPYKLKIGAPAAVQIQYQGKPVDLSRFIRTNQVARLTLNAEQS
                     PAQ"
     gene            complement(13431..14585)
                     /gene="trmG/rlmN"
                     /locus_tag="RHX21_000286"
     CDS             complement(13431..14585)
                     /gene="trmG/rlmN"
                     /locus_tag="RHX21_000286"
                     /EC_number="2.1.1.-"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA
                     (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA
                     large subunit methyltransferase RlmN"
                     /protein_id="HDV1985528.1"
                     /translation="MSEQLVTPENVTTKDGKINLLDLNRQQMREFFKDLGEKPFRADQ
                     VMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQ
                     RVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVG
                     AAKVTGQRPITNVVMMGMGEPLLNLNNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPA
                     LDKLGDMIDVALAISLHAPNDEIRDEIVPINKKYNIETFLAAVRRYLEKSNANQGRVT
                     IEYVMLDHVNDGTEHAHQLAELLKDTPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVL
                     MSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEAIDIKAV"
     gene            complement(14735..15166)
                     /gene="ndk"
                     /locus_tag="RHX21_000287"
     CDS             complement(14735..15166)
                     /gene="ndk"
                     /locus_tag="RHX21_000287"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HDV1985529.1"
                     /translation="MAIERTFSIIKPNAVAKNVIGNIFARFEAAGFKIVGTKMLHLTV
                     EQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLEGENAVQRHRDLLGATNPANALAGT
                     LRADYADSLTENGTHGSDSVESAAREIAYFFGEGEVCPRTR"
     gene            complement(15315..17627)
                     /gene="pbpC"
                     /locus_tag="RHX21_000288"
     CDS             complement(15315..17627)
                     /gene="pbpC"
                     /locus_tag="RHX21_000288"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417014.1"
                     /note="penicillin-binding protein 1C; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase PbpC"
                     /protein_id="HDV1985530.1"
                     /translation="MPRLLTKRGCWITLAAAPFLLFLAAWGADKLWPLPLHEVNPARV
                     VVAQDGTPLWRFADADGIWRYPVTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARA
                     AWQDLTSGRVISGGSTLTMQVARLLDPHPKTFGGKIRQLWRALQLEWHLSKREILTLY
                     LNRAPFGGTLQGIGAASWAYLGKSPANLSYSEAAMLAVLPQAPSRLRPDRWPERAEAA
                     RNKVLERMAVQGAWSREQVKESREEPIWLAPRQMPQLAPLFSRMMLGKSKSDKIVTTL
                     DAGLQRRLEELAQNWKGRLPPRSSLAMIVVDHTDMRVRGWVGSVDLNDDSRFGHVDMV
                     NAIRSPGSVLKPFVYGLALDEGLIHPASLLQDVPRRTGDYRPGNFDSGFHGPISMSEA
                     LVRSLNLPAVQVLEAYGPKRFAAKLRNVGLPLYLPNGAAPNLSLILGGAGAKLEDMAA
                     AYTAFARHGKAGKLRLQPDDPLLERPLMSSGAAWIIRRIMADEAKPLPDSALPRVAPL
                     AWKTGTSYGYRDAWAIGVNARYVIGIWTGRPDGTPVVGQFGFASAVPLLNQVNNILLS
                     RSANLPEDPRPNSVTRGVICWPGGQSLPEGDGNCRRRLATWLLDGSQPPTLLLPEQEG
                     INGIRFPIWLDENGKRVAADCPQARQEMINVWPLPLEPWLPASERRAVRLPPASTICP
                     SYGHDAQLPLQLTGVRDGAIIKRLPGAAEATLPLQSSGGAGERWWFLNGEPLTERGRN
                     VTLHLTDKGDYQLLVMDDVGQIATVKFVMQ"
     gene            complement(17628..22589)
                     /gene="yfhM"
                     /locus_tag="RHX21_000289"
     CDS             complement(17628..22589)
                     /gene="yfhM"
                     /locus_tag="RHX21_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha2-macroglobulin"
                     /protein_id="HDV1985531.1"
                     /translation="MKKLRVAACMLMLALAGCDNNDNAPTAVKKDAPSEVTKAASSEN
                     ASSAKLSVPERQKLAQQSAGKVLTLLDLSEVQLDGAATLVLTFSIPLDPDQDFSRVIH
                     VVDKKSGKVDGAWELSDNLKELRLRHLEPKRDLIVTIGKEVKALNNATFSKDYEKTIT
                     TRDIQPSVGFASRGSLLPGKVVEGLPVMALNVNNVDVNFFRVKPESLPAFISQWEYRN
                     SLANWQSDKLLQMADLVYTGRFDLNPARNTREKLLLPLGDIKPLQQAGVYLAVMNQAG
                     RYDYSNPATLFTLSDIGVSAHRYHNRLDIFTQSLENGAAQQGIEVSLLNEKGQTLTQA
                     TSDAQGHVQLENDKNAALLLARKDGQTTLLDLKLPALDLAEFNIAGAPGYSKQFFMFG
                     PRDLYRPGETVILNGLLRDADGKALPNQPIKLDVIKPDGQVLRSVVSQPENGLYHFTW
                     PLDSNAATGMWHIRANTGDNQYRMWDFHVEDFMPERMALNLTGEKTPLTPKDEVKFSV
                     VGYYLYGAPANGNTLQGQLFLRPLREAVSALPGFEFGDIAAENLSRTLDEVQLTLDDK
                     GRGEVSTESQWKETHSPLQVIFQGSLLESGGRPVTRRAEQAIWPADALPGIRPQFASK
                     SVYDYRTDSTVKQPIVDEGSNAGFDIVYSDAQGVKKAVSGLQVRLIRERRDYYWNWSE
                     DEGWQSQFDQKDLIENEQTLDLQADETGKVSFPVEWGAYRLEVKAPNEAVSSVRFWAG
                     YSWQDNSDGSGAVRPDRVTLKLDKASYRPGDTIKLHIAAPTAGKGYAMVESSEGPLWW
                     QEIDVPAQGLDLTIPVDKTWNRHDLYLSTLVVRPGDKSRSATPKRAVGVLHLPLGDEN
                     RRLDLALETPAKMRPNQPLTVKIKASTKNGEKPKQVNVLVSAVDSGVLNITDYVTPDP
                     WQAFFGQKRYGADIYDIYGQVIEGQGRLAALRFGGDGDELKRGGKPPVNHVNIVAQQA
                     LPVTLNEQGEGSVTLPIGDFNGELRVMAQAWTADDFGSNESKVIVAAPVIAELNMPRF
                     MASGDTSRLTLDITNLTDKPQKLNVALTASGLLELVSDSPAAVELAPGVRTTLFIPVR
                     ALPGYGDGEIQATISGLALPGETVADQHKQWKIGVRPAFPAQTVNYGTALQPGETWAI
                     PADGLQNFSPVTLEGQLLLSGKPPLNIARYIKELKAYPYGCLEQTASGLFPSLYTNAA
                     QLQALGIKGDSDEKRRASVDIGISRLLQMQRDNGGFALWDKNGDEEYWLTAYVMDFLV
                     RAGEQGYSVPTDAINRGNERLLRYLQDPGMMSIPYADNLKASKFAVQSYAALVLARQQ
                     KAPLGALREIWEHRADAASGLPLLQLGVALKTMGDATRGEEAIVLALKTPRNSDERIW
                     LGDYGSPLRDNALMLSLLEENKLLPDEQNTLLNTLSQQAFGERWLSTQESNALFLAAR
                     TIQDLPGKWQAQTSFSAEPLTGEKTLNSNLNSDQLATLQVRNSGDQPLWLRMDASGYP
                     QSAPLPANNVLQIERHILGTDGKSKSLDSLRSGDLVLVWLQVKASNSVPDALVVDLLP
                     AGLELENQNLANGSASLEQSGGEVQNLLNQMQQASIKHIEFRDDRFVAAVAVDEYQPV
                     TLVYLARAVTPGTYQVPQPMVESMYVPQWRATGAAEDLLIVRP"
     gene            22796..23641
                     /gene="sseA"
                     /locus_tag="RHX21_000290"
     CDS             22796..23641
                     /gene="sseA"
                     /locus_tag="RHX21_000290"
                     /EC_number="2.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417016.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-mercaptopyruvate sulfurtransferase"
                     /protein_id="HDV1985532.1"
                     /translation="MSTTWFVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLN
                     GHIPGAVFFDIEALSDHTSPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAP
                     RAWWMLRTFGVEKVSILGGGLAGWQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDV
                     LLASHENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDE
                     LDAIFFGRGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEWGARADLP
                     VEPVK"
     gene            complement(24134..24910)
                     /gene="sseB"
                     /locus_tag="RHX21_000291"
     CDS             complement(24134..24910)
                     /gene="sseB"
                     /locus_tag="RHX21_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708361.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enhanced serine sensitivity protein SseB"
                     /protein_id="HDV1985533.1"
                     /translation="MSETKNELEDLLEKAATEPAHRPAFFRTLLESTVWVPGTAAQGE
                     AVVEDSALDLQHWEKEDGTSVIPFFTSLEALQQAVEDEQAFVVMPVRTLFEMTLGETL
                     FLNAKLPTGKEFMPREISLLIGEEGNPLSSQEILEGGESLILSEVAEPPAQMIDSLTT
                     LFKTIKSVKRAFICSIKENEEAQPNLLIGIEADGDIEEIIQATGSVATDTLPGDEPID
                     ICQVKKGEKGISHFITEHIVPFYERRWGGFLRDFKQNRII"
     gene            complement(25052..26335)
                     /gene="pepB"
                     /locus_tag="RHX21_000292"
     CDS             complement(25052..26335)
                     /gene="pepB"
                     /locus_tag="RHX21_000292"
                     /EC_number="3.4.11.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311416.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase PepB"
                     /protein_id="HDV1985534.1"
                     /translation="MTEAMKITLSTQPADARWGEKATYSINNDGITLHLNGADDLGLI
                     QRAARKIDGLGIKHVQLSGEGWDADRCWAFWQGYKAPKGTRKVEWPDLDDAQRQELDN
                     RLMIIDWVRDTINAPAEELGPSQLAQRAVDLISNVAGDRVTYRITKGEDLREQGYMGL
                     HTVGRGSERSPVLLALDYNPTGDKEAPVYACLVGKGITFDSGGYSIKQTAFMDSMKSD
                     MGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIITYRNGKKVEVMNT
                     DAEGRLVLADGLIDASAQKPEMIIDAATLTGAAKTALGNDYHALFSFDDALAGRLLAS
                     ASQENEPFWRLPLAEFHRSQLPSNFAELNNTGSAAYPAGASTAAGFLSHFVENYQQGW
                     LHIDCSATYRKAPVEQWSAGATGLGVRTIANLLTA"
     gene            complement(26513..26713)
                     /gene="iscX"
                     /locus_tag="RHX21_000293"
     CDS             complement(26513..26713)
                     /gene="iscX"
                     /locus_tag="RHX21_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004104502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein IscX"
                     /protein_id="HDV1985535.1"
                     /translation="MGLKWTDSREIGEALYDAYPDLDPKTVRFTDMHQWICDLEDFDD
                     DPQASNEKILEAILLVWLDEAE"
     gene            complement(26725..27060)
                     /gene="fdx"
                     /locus_tag="RHX21_000294"
     CDS             complement(26725..27060)
                     /gene="fdx"
                     /locus_tag="RHX21_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015683702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISC system 2Fe-2S type ferredoxin"
                     /protein_id="HDV1985536.1"
                     /translation="MPKIVILPHQDLCPDGAVLEANSGETILDAALRNGIEIEHACEK
                     SCACTTCHCIVREGFDSLPESSEQEDDMLDKAWGLEPESRLSCQARVTDEDLVVEIPR
                     YTINHAREH"
     gene            complement(27062..28912)
                     /gene="hscA"
                     /locus_tag="RHX21_000295"
     CDS             complement(27062..28912)
                     /gene="hscA"
                     /locus_tag="RHX21_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S protein assembly chaperone HscA"
                     /protein_id="HDV1985537.1"
                     /translation="MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETL
                     ADHEGRHLLPSVVHYQQQGHSVGYDARTNAALDTANTISSVKRLMGRSLADIQQRYPH
                     LPYQFQASENGLPMIETAAGLLNPVRVSADILKALAARATEALAGELDGVVITVPAYF
                     DDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGQEGVIAVYDLGGGTFDISIL
                     RLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIPDRSDNRVQRELLDAAIAAKI
                     ALSDADSVTVNVAGWQGEISREQFNELIAPLVKRTLLACRRALKDAGVEADEVLEVVM
                     VGGSTRVPLVRERVGEFFGRPPLTSIDPDKVVAIGAAIQADILVGNKPDSEMLLLDVI
                     PLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRS
                     LARFALRGIPALPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLTDSE
                     IASMIKDSMSYAEQDVKARMLAEQKVEAARVLESLHGALAADAALLSAAERQVIDDAA
                     AHLSEVAQGDDVDAIEQAIKNVDKQTQDFAARRMDQSVRRALKGHSVDEV"
     gene            complement(28929..29444)
                     /gene="hscB"
                     /locus_tag="RHX21_000296"
     CDS             complement(28929..29444)
                     /gene="hscB"
                     /locus_tag="RHX21_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone HscB"
                     /protein_id="HDV1985538.1"
                     /translation="MDYFTLFGLPARYQLDTQALSLRFQDLQRQYHPDKFASGSQAEQ
                     LAAVQQSATINQAWQTLRHPLMRAEYLLSLHGFDLASEQHTVRDTAFLMEQLELREEL
                     DEIEQAKDEARLESFIKRVKKMFDTRHQLMVEQLDNEAWDAAADTVRKLRFLDKLRSS
                     AEQLEEKLLDF"
     gene            complement(29540..29863)
                     /gene="iscA"
                     /locus_tag="RHX21_000297"
     CDS             complement(29540..29863)
                     /gene="iscA"
                     /locus_tag="RHX21_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster assembly protein IscA"
                     /protein_id="HDV1985539.1"
                     /translation="MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEF
                     VDEPTPEDIVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFTNPNVKDECGCG
                     ESFHV"
     gene            complement(29880..30266)
                     /gene="iscU"
                     /locus_tag="RHX21_000298"
     CDS             complement(29880..30266)
                     /gene="iscU"
                     /locus_tag="RHX21_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold IscU"
                     /protein_id="HDV1985540.1"
                     /translation="MAYSEKVIDHYENPRNVGSFDNNDENVGSGMVGAPACGDVMKLQ
                     IKVNDEGIIEDARFKTYGCGSAIASSSLVTEWVKGKSLDEAQAIKNTDIAEELELPPV
                     KIHCSILAEDAIKAAIADYKSKREAK"
     gene            complement(30294..31508)
                     /gene="iscS"
                     /locus_tag="RHX21_000299"
     CDS             complement(30294..31508)
                     /gene="iscS"
                     /locus_tag="RHX21_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017459011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDV1985541.1"
                     /translation="MKLPIYLDYSATTPVDPRVAEKMMQFMTMDGTFGNPASRSHRFG
                     WQAEEAVDIARNQIADLVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKT
                     EHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLKELEAAMRDDTILVSIMHVNNEIGVV
                     QDIAAIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIYGPKGIGALYV
                     RRKPRVRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMATEMERLRGLRNR
                     LWNGIKDIEEVYLNGDLEHGAPNILNVSFNYVEGESLIMALKDLAVSSGSACTSASLE
                     PSYVLRALGLNDELAHSSIRFSLGRFTTEEEIDYTIELVRKSIGRLRDLSPLWEMYKQ
                     GVDLNSIEWAHH"
     gene            complement(31620..32108)
                     /gene="iscR"
                     /locus_tag="RHX21_000300"
     CDS             complement(31620..32108)
                     /gene="iscR"
                     /locus_tag="RHX21_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly transcriptional regulator
                     IscR"
                     /protein_id="HDV1985542.1"
                     /translation="MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQ
                     LFSRLRKNGLVSSVRGPGGGYLLGKDASSIAVGEVISAVDESVDATRCQGKGGCQGGD
                     KCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRTRIQDAIDVKL
                     RA"
     gene            complement(32409..33146)
                     /gene="trmJ"
                     /locus_tag="RHX21_000301"
     CDS             complement(32409..33146)
                     /gene="trmJ"
                     /locus_tag="RHX21_000301"
                     /EC_number="2.1.1.200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ"
                     /protein_id="HDV1985543.1"
                     /translation="MLQNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVKPDS
                     QAIALAAGASDVIGNAHIVDTLDEALAGCSLVVGTSARSRTLPWPMLDPRECGLKSVA
                     EAANTPVALVFGRERVGLTNEELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEVRMAW
                     LATQENGEQVEHEETPYPLVDDLERFYGHLEQTLLATGFIRENHPGQVMNKLRRLFTR
                     ARPESQELNILRGILASIEQQNKGNKA"
     gene            33265..34068
                     /gene="suhB"
                     /locus_tag="RHX21_000302"
     CDS             33265..34068
                     /gene="suhB"
                     /locus_tag="RHX21_000302"
                     /EC_number="3.1.3.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000553460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol-1-monophosphatase"
                     /protein_id="HDV1985544.1"
                     /translation="MHPMLNIAVRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVD
                     KAAEAVIIDTIRKSYPQHTIITEESGELEGTDQDVQWVIDPLDGTTNFIKRLPHFAVS
                     IAVRIKGRTEVAVVYDPMRNELFTATRGQGAQLNGYRLRGSTARDLDGTILATGFPFK
                     AKQYATTYINIVGKLFNECADFRRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGEL
                     LVREAGGIVSDFTGGHNYMLTGNIVAGNPRVVKAMLANMRDELSDALKR"
     gene            34213..35067
                     /locus_tag="RHX21_000303"
     CDS             34213..35067
                     /locus_tag="RHX21_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311427.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDV1985545.1"
                     /translation="MALPVNKRVPKILFILFVVAFCVYLVPRVAINFFYYPDDKIYGP
                     DPWSAESVEFTAKDGTRLQGWFIPSSTGPADNAIATIIHAHGNAGNMSAHWPLVSWLP
                     ERNFNVFMFDYRGFGKSKGTPSQAGLLDDTQSAINVVRHRSDVNPQRLVLFGQSIGGA
                     NILAVIGQGDREGIRAVILDSTFASYATIANQMIPGSGYLLDESYSGENYIASVSPIP
                     LLLIHGKADHVIPWQHSEKLYSLAKEPKRLILIPDGEHIDAFSDRHGDVYREQMVDFI
                     LSALNPQN"
     gene            35258..36538
                     /gene="csiE"
                     /locus_tag="RHX21_000304"
     CDS             35258..36538
                     /gene="csiE"
                     /locus_tag="RHX21_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stationary phase inducible protein CsiE"
                     /protein_id="HDV1985546.1"
                     /translation="MMPTLAPPSVLSAPQRRCQILLTLFQPGLTATTATFSELNGVDD
                     DIASLDISETGQEILRYHQLTLTAGYDGSYRVEGTVLNQRLCLFHWLRRGFRLCPSFI
                     TSHFTPALKSELKRRGIARNFYDDTNLQALVNLCSRRLQKRFETRDIHFLCLYLQYCL
                     LQHHAGITPQFNPLQRRWAESCLEFQVAQEIGRHWQRRALQPVPPDEPLFMALLFSML
                     RVPDPLRDAHQRDRQLRQSIKRLVNHFRELGNVRFYDEQGLCDQLYTHLAQALNRSLF
                     AIGIDNTLPEEFARLYPRLVRTTRAALAGFESEYGVHLSDEESGLVAVIFGAWLMQEN
                     DLHEKQIILLTGNDSEREAQIEQQLRELTLLPLNIKHMSVKAFLQTGAPRGAALIIAP
                     YTMPLPLFSPPLIYTDLTLTTHQQEQIRKMLESA"
     gene            complement(36530..37669)
                     /locus_tag="RHX21_000305"
     CDS             complement(36530..37669)
                     /locus_tag="RHX21_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate MFS transporter"
                     /protein_id="HDV1985547.1"
                     /translation="MVLQSTRWLALGYFTYFFSYGIFLPFWSVWLKGIGLTPETIGLL
                     LGAGLVARFLGSLLIAPRVSDPSRLISALRVLALLTLLFAVAFWAGAHVAWLMLVMIG
                     FNLFFSPLVPLTDALANTWQKQFPLDYGKVRLWGSVAFVIGSALTGKLVTMFDYRVIL
                     ALLTLGVASMLLGFLIRPTIQPQGASRQQESTGWSAWLALVRQNWRFLACVCLLQGAH
                     AAYYGFSAIYWQAAGYSASAVGYLWSLGVVAEVIIFALSNKLFRRCSARDMLLISAIC
                     GVVRWGIMGATTALPWLIVVQILHCGTFTVCHLAAMRYIAARQGSEVIRLQAVYSAVA
                     MGGSIAIMTVFAGFLYQYLGHGVFWVMALVALPAMFLRPKVVPSC"
     gene            complement(37829..38719)
                     /gene="hcaR"
                     /locus_tag="RHX21_000306"
     CDS             complement(37829..38719)
                     /gene="hcaR"
                     /locus_tag="RHX21_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator HcaR"
                     /protein_id="HDV1985548.1"
                     /translation="MELRHLRYFVAVAQALNFTRAAEKLHTSQPSLSSQIRDLENCVG
                     VPLLVRDKRKVALTAAGECFLQDALAILEQAENAKLRARKIVQEDRQLTIGFVPSAEV
                     NLLPKVLPMFRLRQPDTLIELVSLITTQQEEKIRRGELDVGLMRHPVYSPEIDYLELF
                     DEPLVVVLPVDHPLAHEKEITAAQLDGVNFVSTDPAYSGSLAPIVKAWFAQENSQPNI
                     VQVATNILVTMNLVGMGLGVTLIPGYMNNFNTGQVVFRPIAGNVPSIALLMAWKKGEM
                     KPALRDFIAIVQERLANVTA"
     gene            38855..40216
                     /locus_tag="RHX21_000307"
     CDS             38855..40216
                     /locus_tag="RHX21_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic ring-hydroxylating dioxygenase subunit
                     alpha"
                     /protein_id="HDV1985549.1"
                     /translation="MTTPSDLNIYQLIDTQNGRVTPRIYTDPDIYQLELERIFGRCWL
                     FLAHESQIPKPGDFFNTYMGEDAVVVVRQKDGSIKAFLNQCRHRAMRVSYADCGNTRA
                     FTCPYHGWSYGINGELIDVPLEPRAYPQGLCKSHWGLNEVPCVESYKGLIFGNWDTSA
                     PGLRDYLGDIAWYLDGMLDRREGGTEIVGGVQKWVINCNWKFPAEQFASDQYHALFSH
                     ASAVQVLGAKDDGSDKRLGDGQTARPVWETAKDALQFGQDGHGSGFFFTEKPDANVWV
                     DGAVSSYYRETYAEAEQRLGEVRALRLAGHNNIFPTLSWLNGTATLRVWHPRGPDQVE
                     VWAFCITDKAASDEVKAAFENSATRAFGPAGFLEQDDSENWCEIQKLLKGHRARNSKL
                     CLEMGLGQEKRRDDGIPGITNYIFSETAARGMYQRWADLLSSESWQEVLDKTAAYQQE
                     VMK"
     gene            40213..40731
                     /locus_tag="RHX21_000308"
     CDS             40213..40731
                     /locus_tag="RHX21_000308"
                     /EC_number="1.14.12.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate/cinnamic acid dioxygenase
                     subunit beta"
                     /protein_id="HDV1985550.1"
                     /translation="MSAQVSLELHHRISQFLFHEASLLDDWKFRDWLAQLDEEIRYTM
                     RTTVNAQTRDRRKGVQPPTTWIFNDTKDQLERRIARLETGMAWAEEPPSRTRHLISNC
                     QISETDIPNVFAVRVNYLLYRAQKERDETFYVGTRFDKVRRLEDDNWRLLERDIVLDQ
                     AVITSHNLSVLF"
     gene            40731..41051
                     /locus_tag="RHX21_000309"
     CDS             40731..41051
                     /locus_tag="RHX21_000309"
                     /EC_number="1.14.12.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-phenylpropionate/cinnamic acid
                     dioxygenase ferredoxin subunit"
                     /protein_id="HDV1985551.1"
                     /translation="MNRIYACPVADVPEGEALRIDTSPVIALFNVGGEFYAINDRCSH
                     GNASMSEGYLEDDATVECPLHAASFCLKTGKALCLPATDPLTTYPVHVEGGDIFIDLP
                     EAQP"
     gene            41048..41860
                     /gene="hcaB"
                     /locus_tag="RHX21_000310"
                     /gene_synonym="phdD"
                     /gene_synonym="yfhX"
     CDS             41048..41860
                     /gene="hcaB"
                     /locus_tag="RHX21_000310"
                     /gene_synonym="phdD"
                     /gene_synonym="yfhX"
                     /EC_number="1.3.1.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate-dihydrodiol/cinnamic
                     acid-dihydrodiol dehydrogenase"
                     /protein_id="HDV1985552.1"
                     /translation="MSDLHNESIFITGGGSGLGLALVERFIEEGAQVATLELSAAKVA
                     SLRQRFGEHILAVEGNVTCYADYQRAVDQILTRSGKLDCFIGNAGIWDHNASLVNTPA
                     ETLETGFHELFNVNVLGYLLGAKACAPALIASEGSMIFTLSNAAWYPGGGGPLYTASK
                     HAATGLIRQLAYELAPKVRVNGVGPCGMASDLRGPQALGQSETSIMQSLTPEKIAAIL
                     PLQFFPQPADFTGPYVMLASRRNNRALSGVMINADAGLAIRGIRHVAAGLDL"
     gene            41870..43072
                     /locus_tag="RHX21_000311"
     CDS             41870..43072
                     /locus_tag="RHX21_000311"
                     /EC_number="1.14.12.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylpropionate dioxygenase ferredoxin
                     reductase subunit"
                     /protein_id="HDV1985553.1"
                     /translation="MKEKTIIIVGGGQAAAMAAASLRQQGFTGELHLFSDERHLPYER
                     PPLSKSMLLEDSPQLQQVLPANWWQENNVHLHSGVTIKTLGRDTRELVLTNGESWHWD
                     QLFIATGAAARPLPLLDALGERCFTLRHAGDAARLREVLQPERSVVIVGAGTIGLELA
                     ASATQRRCKVTVIELAATVMGRNAPPPVQRYLLQRHQQAGVRILLNNAIEHVVDGEKV
                     ELTLQSGETLQADVVIYGIGISANEQLAREANLDTANGIVIDEACRTCDPAIFAGGDV
                     AITRLDNGALHRCESWENANNQAQIAAAAMLGLPLPLLPPPWFWSDQYSDNLQFIGDM
                     RGDDWLCRGNPETQKAIWFNLQNGVLIGAVTLNQGREIRPIRKWIQSGKTFDAKLLID
                     ENIALKSL"
     gene            43169..43591
                     /locus_tag="RHX21_000312"
     CDS             43169..43591
                     /locus_tag="RHX21_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417038.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HDV1985554.1"
                     /translation="MNTLRYFDFGAARPVLLLIARIAVVLIFIIFGFPKMMGFDGTVQ
                     YMASLGAPMPMLAAIIAVVMEVPAAILIVLGFFTRPLAVLFIFYTLGTAVIGHHYWDM
                     TGDAVGPNLINFWKNVSIAGAFLLLAITGPGAISLDRR"
     gene            complement(43639..44511)
                     /locus_tag="RHX21_000313"
     CDS             complement(43639..44511)
                     /locus_tag="RHX21_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase"
                     /protein_id="HDV1985555.1"
                     /translation="MTIYTLSHGSLKLDVSDQGGVIEGFWRDTTPLLRPGKKSGVATD
                     ASCFPLVPFANRVSGNRFVWQGREYQLQPNVEWDAHYLHGDGWLGEWQCVSHSDDSLC
                     LVYEHRSGVYHYRVSQAFHLTADTLMVTLSVTNQGAETLPFGTGWHPYFPLSPQTRIQ
                     AQASGYWLEREQWLAGEFCEQLPQELDFNQLAPLPRQWVNNGFAGWNGQARIEQPQEG
                     YAIIMETTPPAPCYFIFVSDPAFDKGYAFDFFCLEPMSHAPDDHHRPEGGDLIALAPG
                     ESTTSEMSLRVEWL"
     gene            complement(44523..45617)
                     /locus_tag="RHX21_000314"
     CDS             complement(44523..45617)
                     /locus_tag="RHX21_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HDV1985556.1"
                     /translation="MKINRIVNEGFMKTMLAAYLPGNSTVDLREVAVPTPGINQVLIK
                     MKSSGICGSDVHYIYHQHRATAAAPDKPLYQGFINGHEPCGQIVAMGQGCRHFKEGDR
                     VLVYHISGCGFCPNCRRGFPISCTGKGKAAYGWQRDGGHAEYLLAEEKDLILLPDALS
                     YEDGAFISCGVGTAYEGILRGEVSGSDNVLVVGLGPVGMMAMMLAKGRGAKRIIGVDM
                     LPERLAMAKQLGVMDHGYLATTEGLPQIIAELTHGGADVALDCSGNAAGRLLALQSTA
                     DWGRVVYIGETGKVEFEVSADLMHHQRRIIGSWVTSLFHMEKCAHDLTDWKLWPRNAI
                     THRFSLEQAGDAYALMASGKCGKVVINFPD"
     gene            complement(45650..46648)
                     /locus_tag="RHX21_000315"
     CDS             complement(45650..46648)
                     /locus_tag="RHX21_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV1985557.1"
                     /translation="MSASSLPLPQGKSVSLKQFVSRHINEIGLLVVIAILYLVFSLNA
                     PGFISLNNQMNVLRDAATIGIAAWAMTLIIISGEIDVSVGPMVAFVSVCLAFLLQFEV
                     PLAIACLLVLLLGALMGTLAGVLRGVFNVPSFVATLGLWSALCGMGLFMTNALPVPID
                     ENEVLDWLGGQFLGVPVSALIMIVLFALFVFISRKTAFGRSVFAVGGNATAAQLCGIN
                     VRRVRILIFTLSGLLAAVTGILLAARLGSGNAGAANGLEFDVIAAVVVGGTALSGGRG
                     SLFGTLLGVLVITLIGNGLVLLGINSFFQQVVRGVIIVVAVLANILLTQRSSKAKR"
     gene            complement(46673..48184)
                     /locus_tag="RHX21_000316"
     CDS             complement(46673..48184)
                     /locus_tag="RHX21_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDV1985558.1"
                     /translation="MFTATEAVPVAKVVAGNKRYPGVVALDNVNFTLNKGEVRALLGK
                     NGAGKSTLIRMLTGSERPDSGDIWIGETRLEGDEATLTRRAAELGVRAVYQELSLVEG
                     LTVAENLCLGQWPRRNGMIDYLQMAQDAQRCLQALGVDVSPEQLVSTLSPAQKQLVEI
                     ARVMKGEPRVVILDEPTSSLASAEVELVISAVKKMSALGVAVIYVSHRMEEIRRIASC
                     ATVMRDGQVAGDVMLENTSTHHIVSLMLGRDHVDIAPVAPQEIVDQAVLEVRALRHKP
                     KLEDISFTLRRGEVLGIAGLLGAGRSELLKAIVGLETYEQGEIVINGEKIMRPDYGDM
                     LKRGIGYTPENRKEAGIIPWLGVDENTVLTNRQKISTNGVLQWSTIRRLTEEVMQRMT
                     VKAASSETPIGTLSGGNQQKVVIGRWVYAASQILLLDEPTRGVDIEAKQQIYRIVREL
                     AAEGKSVVFISSEVEELPLVCDRILLLQHGTFSQEFHSPVNVDELMSAILSVH"
     gene            complement(48207..49190)
                     /locus_tag="RHX21_000317"
     CDS             complement(48207..49190)
                     /locus_tag="RHX21_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDV1985559.1"
                     /translation="MPKKMRTTRNLLLMATLLGSALFARAAEKEMTIGAIYLDTQGYY
                     AGVRQGVQDAAKDSSVQVQLIETNAQGDISKESTFVDTLVARNVDAIILSAVSENGSS
                     RTVRRASEAGIPVICYNTCINQKGVDKYVSAYLVGDPLEFGKKLGNAAADYFIANKID
                     QPKIAVINCEAFEVCVQRRKGFEEVLKSRVPGAQIVANQEGTVLDKAISVGEKLIIST
                     PDLNAIMGESGGATLGAVKAVRNQNQAGKIAVFGSDMTTEIAQELENNQVLKAVVDIS
                     GKKMGNAVLAQTLKVINKQADGEKVIQVPIDLYTKTEDGKQWLATHVDGLP"
     gene            complement(49287..52568)
                     /locus_tag="RHX21_000318"
     CDS             complement(49287..52568)
                     /locus_tag="RHX21_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417044.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5107 domain-containing protein"
                     /protein_id="HDV1985560.1"
                     /translation="MTPVKVWQERVEIPTYETGPQDIHPMFLENRVYQGSSGAVYPYG
                     VTDTLSEQKTLKSWQAVWLENDYIKVMILPELGGRVHRAWDKVKQRDFVYHNEVIKPA
                     LVGLLGPWISGGIEFNWPQHHRPTTFMPVDFTLEAHEDGAQTVWVGETEPMHGLQVMT
                     GFTLRPERAALEIASRVYNGNATPRHFLWWANPAVKGGEGHQSVFPPDVTAVFDHGKR
                     AVSAFPIATGTYYKVDYSAGVDISRYKNVPVPTSYMAEKSQYDFVGAWCHDEDGGLLH
                     VANHHIAPGKKQWSWGHSEFGQAWDKSLTDNNGPYIELMTGIFADNQPDFTWLDAYEE
                     KRFEQYFLPYHSLGMVQNASRDAVIKLQRSERGIEWGLYAISPLNGYRLAIREIGKCN
                     ALLDDAVALMPATAIQGVLHGINPERLTIELSDADGNIVLSYQEHQPQELPLPDVAKA
                     PLSAQDITSTDEAWFIGQHLEQYHHASRSPFDYYLRGVALDPLDYRCNLALAMLEYNR
                     ADFPQAVAYATQALKRAHALNKNPQCGQASLIRASAYERQGQYQQAEEDFWRAVWSGN
                     SKAGGYYGLARLAARNGNFDAGLDFCQQSLRACPTNQEVLCLHNLLLVLSGRQDNARV
                     QREKLLRDYPLNATLWWLNWFDGRSESALAQWRGLCQGRDVNALMTAGQLINWGMPTL
                     ATEMLNALDCQRTLSLYLQASLLPKAERGELVAKAIDVFPQFVRFPNTLEEVAALESI
                     EECWFARHLLACFYYNKRSYNKAITLWQRCVEMSPEFADGWRGLAIHAWNKQHDYELA
                     ARYLDNAYQLAPQDARLLFERDLLDKLSGATPEKRLARLENNLEIALKRDDMTAELLN
                     LWHLTGQADKAADILATRKFHPWEGGEGKVTSQFILNQLLRAWQHLDARQPQQASELL
                     HAALHYPENLSEGRLPGQTDNDIWFWQAICANAQGDETEAMRCLRLAATGDRTINIHS
                     YYNDQPVDYLFWQGMALRLLGEQHTAQQLFSEMKQWAQEMAKTSIEADFFAVSQPDLL
                     SLYGDLQQQHKEKCLMVAMLASAGLGEVAQYESARAELTAINPAWPKAALFTTVMPFI
                     FNYVH"
     gene            52686..53879
                     /locus_tag="RHX21_000319"
     CDS             52686..53879
                     /locus_tag="RHX21_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311443.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDV1985561.1"
                     /translation="MRACINNQQIRHHNKCVILELLYRQKRANKSTLARLAQISIPAV
                     SNILQELESEKRVVNIDDESQTRGHSSGTWLIAPEGDWTLCLNVTPTSIECQVANACL
                     SPKGEFEYLQIDVPTPQALLSEIEKCWHRHRKLWPDRTINLALAIHGQVDPVTGVSQT
                     MPQAPWTTPVEVKYLLEEKLGIRVMVDNDCVMLALAEKWQNNSQERDFCVINVDYGIG
                     SSFVINEQIYRGSLYGSGQIGHTIVNPDGVVCDCGRYGCLETVASLSALKKQARVWLK
                     SQPVNTQLDPEKLTTAQLIAAWQSGEPWITSWVDRSANAIGLSLYNFLNILNINQIWL
                     YGRSCAFGENWLNTIIRQTGFNPFDRDEGPSVKATQIGFGQLSRAQQVLGIGYLYVEA
                     QLRQI"
     gene            complement(53943..55196)
                     /gene="glyA"
                     /locus_tag="RHX21_000320"
     CDS             complement(53943..55196)
                     /gene="glyA"
                     /locus_tag="RHX21_000320"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDV1985562.1"
                     /translation="MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVM
                     QAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRAKELFGADYANVQPHSGSQAN
                     FAVYTALLEPGDTVLGMNLAHGGHLTHGSPVNFSGKLYNIVPYGIDATGHIDYADLEK
                     QAKEHKPKMIIGGFSAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVP
                     HAHVVTTTTHKTLAGPRGGLILAKGGSEELYKKLNSAVFPGGQGGPLMHVIAGKAVAL
                     KEAMEPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEAD
                     AALGRANITVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWMCDVLDS
                     INDEAVIERIKGKVLDICARYPVYA"
     gene            55524..56714
                     /gene="hmpA"
                     /locus_tag="RHX21_000321"
     CDS             55524..56714
                     /gene="hmpA"
                     /locus_tag="RHX21_000321"
                     /EC_number="1.14.12.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NO-inducible flavohemoprotein"
                     /protein_id="HDV1985563.1"
                     /translation="MLDAQTIATVKATIPLLVETGPKLTAHFYDRMFTHNPELKEIFN
                     MSNQRNGDQREALFNAIAAYASNIENLPALLPAVEKIAQKHTSFQIKPEQYNIVGEHL
                     LATLDEMFSPGQEVLDAWGKAYGVLANVFINREAEIYNENASKAGGWEGTRDFRIVAK
                     TPRSALITSFELEPVDGGAVAEYRPGQYLGVWLKPEGFPHQEIRQYSLTRKPDGKGYR
                     IAVKREEGGQVSNWLHNHANVGDVVKLVAPAGDFFMAVADDTPVTLISAGVGQTPMLA
                     MLDTLAKAGHTAQVNWFHAAENGDVHAFADEVKELGQSLPRFTAHTWYRQPSEADRAK
                     GQFDSEGLMDLSKLEGAFSDPTMQFYLCGPVGFMQFTAKQLVDLGVKQENIHYECFGP
                     HKVL"
     gene            complement(56759..57097)
                     /gene="glnB"
                     /locus_tag="RHX21_000322"
     CDS             complement(56759..57097)
                     /gene="glnB"
                     /locus_tag="RHX21_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017373484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulatory protein P-II"
                     /protein_id="HDV1985564.1"
                     /translation="MKKIDAIIKPFKLDDVREALAEVGITGMTVTEVKGFGRQKGHTE
                     LYRGAEYMVDFLPKVKIEIVVPDDIVDTCVDTIIRTAQTGKIGDGKIFVFDVARVIRI
                     RTGEEDDAAI"
     gene            complement(57158..58492)
                     /gene="glrR"
                     /locus_tag="RHX21_000323"
     CDS             complement(57158..58492)
                     /gene="glrR"
                     /locus_tag="RHX21_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator GlrR"
                     /protein_id="HDV1985565.1"
                     /translation="MSHKPAHLLLVDDDPGLLKLLGLRLTSEGYSVVTAESGAEGLRV
                     LNREKVDLVISDLRMDEMDGMQLFAEIQKVQPGMPVIILTAHGSIPDAVAATQQGVFS
                     FLTKPVDKDALYQAIDDALEQSAPATDERWREAIVTRSPLMLRLLEQARLVAQSDVSV
                     LINGQSGTGKEIFAQAIHNASPRNSKPFIAINCGALPEQLLESELFGHARGAFTGAVS
                     NREGLFQAAEGGTLFLDEIGDMPAPLQVKLLRVLQERKVRPLGSNRDIDIDVRIISAT
                     HRDLPKAMARGEFREDLYYRLNVVSLKIPALAERTEDIPLLANHLLRQAAERHKPFVR
                     AFSTDAMKRLMTASWPGNVRQLVNVIEQCVALTSSPVISDALVEQALEGENTALPTFV
                     EARNQFELNYLRKLLQITKGNVTHAARMAGRNRTEFYKLLSRHELDANDFKE"
     gene            complement(58482..59195)
                     /gene="qseG"
                     /locus_tag="RHX21_000324"
     CDS             complement(58482..59195)
                     /gene="qseG"
                     /locus_tag="RHX21_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system QseEF-associated
                     lipoprotein QseG"
                     /protein_id="HDV1985566.1"
                     /translation="MRHIFQRLLPRRLWLAGLPCLALLGCVQSHNKPAIDTPAEEKIP
                     VYQLADYLSTECSDIWALQGKSTETNPLYWLRAMDCADRLMPAQSRQQARQYDDGSWQ
                     NTFKQGILLADAKITPYERRQLVARIDALSTEIPAQVRPLYQLWRDGQALQLQLAEER
                     QRYGKLQQASDSELDTLRQQHHVLQQQLELTTRKLENLTDIERQLSTRKPAGNFSPDT
                     PHEGEKPAPSTHEVTPDEP"
     gene            complement(59360..60787)
                     /gene="qseE"
                     /locus_tag="RHX21_000325"
     CDS             complement(59360..60787)
                     /gene="qseE"
                     /locus_tag="RHX21_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417051.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two component system sensor histidine kinase
                     QseE/GlrK"
                     /protein_id="HDV1985567.1"
                     /translation="MKRWPVFPRSLRQLVMLAFLLILLPLLVLAWQAWQSLNALSDQA
                     ALVNRTTLIDARRSEAMTNAALEMERSYRQYCVLDDPTLAKVYQSQRKRYSEMLDAHA
                     GVLPDDKLYQALRQDLNNLAQLQCNNSGPDAAAAARLEAFASANTEMVQATRTVVFSR
                     GQQLQREIAERGQYFGWQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLG
                     NSVSFSGPSELRSVGQRILWLSERLSWLESQRHQFLRHLSHELKTPLASMREGTELLA
                     DQVVGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQADSAVELENVELAPLVETV
                     VSAHSLPARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSL
                     HGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQG
                     ELYLVDESGQDVCFRIELPSSKNTK"
     gene            complement(61363..65250)
                     /gene="purL"
                     /locus_tag="RHX21_000326"
                     /gene_synonym="purI"
     CDS             complement(61363..65250)
                     /gene="purL"
                     /locus_tag="RHX21_000326"
                     /gene_synonym="purI"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HDV1985568.1"
                     /translation="MMEILRGSPALSAFRINKLLARFQAARLPVHNIYAEYVHFADLN
                     APLNDDEHAQLERLLKYGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQ
                     VNRLERGVAYYIEAGTLTNEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTS
                     VDLLGQGRQALIDANLRLGLALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCR
                     HKIFNADWVIDGEQQPKSLFKMIKNTFETTPDYVLSAYKDNAAVMEGSEVGRYFADHE
                     TGRYDFHQEPAHILMKVETHNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVG
                     FSVSNLRIPGFEQPWEEDFGKPERIVTALDIMTEGPLGGAAFNNEFGRPALNGYFRTY
                     EEKVNSHNGEELRGYHKPIMLAGGIGNIRADHVQKGEINVGAKLVVLGGPAMNIGLGG
                     GAASSMASGQSDADLDFASVQRDNPEMERRCQEVIDRCWQLGDANPILFIHDVGAGGL
                     SNAMPELVSDGGRGGKFELRDILSDEPGMSPLEIWCNESQERYVLAVAADQLPLFDEL
                     CKRERAPYAVIGEATEELHLSLHDRHFDNQPIDLPLDVLLGKTPKMTRDVQTLKAKGD
                     ALVREGITIADAVKRVLHLPTVAEKTFLVTIGDRSVTGMVARDQMVGPWQVPVANCAV
                     TTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEALTNIAATQIGDIKRIKLSANW
                     MAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSMKTRWQEGNEEREMTSPL
                     SLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGATALAQVYRQLGDKPAD
                     VRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFAGHCGINADIASLGD
                     DRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHYVGQAVSGDRFVITANGQT
                     VFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVKLSFDINEDVA
                     APYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLTGRTGLEDFHAL
                     VACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQMMSNLRE
                     LIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRVEVR
                     DAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITSITTESGRVTIMMPHPE
                     RVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG"
     gene            65508..67064
                     /gene="mltF"
                     /locus_tag="RHX21_000327"
     CDS             65508..67064
                     /gene="mltF"
                     /locus_tag="RHX21_000327"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417053.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     MltF"
                     /protein_id="HDV1985569.1"
                     /translation="MKKLKINYLFIGILALLLAVALWPSIPWFGKADNRIAAIQARGE
                     LRVSTIHTPLTYNEINGKPFGLDYELAKQFADYLGVKLKVTVRQNISQLFDDLDNGNA
                     DLLAAGLVYNSERVKNYQPGPTYYSVSQQLVYKVGQYRPRTLGNLTAEQLTVAPGHVV
                     VNDLQTLKDTKFPELSWKVDDKKGSAELMEDVIEGKLDYTIADSVAISLFQRVHPELA
                     VALDITDEQPVTWFSPLDGDNTLSAALLDFFNEMNEDGTLARIEEKYLGHGDDFDYVD
                     TRTFLRAVDAVLPQLKPLFEKYAEEIDWRLLAAIAYQESHWDAQATSPTGVRGMMMLT
                     KNTAQSLGITDRTDAEQSISGGVRYLQDMMSKVPESVPENERIWFALAAYNMGYAHML
                     DARALTAKTKGNPDSWADVKQRLPLLSQKPYYSKLTYGYARGHEAYAYVENIRKYQIS
                     LVGYLQEKEKQATEAAMQLAQDYPAVSPTELGKEKFPFLSFLSQSSSNYLTHSPSLLF
                     SRKGSEEKQN"
     gene            complement(67061..67597)
                     /gene="tadA"
                     /locus_tag="RHX21_000328"
     CDS             complement(67061..67597)
                     /gene="tadA"
                     /locus_tag="RHX21_000328"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HDV1985570.1"
                     /translation="MRRAFITGVFFLSEVEFSHEYWMRHALTLAKRAWDEREVPVGAV
                     LVHNNRVIGEGWNRPIGRHDPTAHAEIMALRQGGLVMQNYRLIDATLYVTLEPCVMCA
                     GAMIHSRIGRVVFGARDAKTGAAGSLMDVLHHPGMNHRVEITEGILADECAALLSDFF
                     RMRRQEIKAQKKAQSSTD"
     gene            complement(67622..68257)
                     /gene="yfhb"
                     /locus_tag="RHX21_000329"
     CDS             complement(67622..68257)
                     /gene="yfhb"
                     /locus_tag="RHX21_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417055.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase C"
                     /protein_id="HDV1985571.1"
                     /translation="MATHERRVVFFDLDGTLHQQDMFGSFLRYLLRRQPLNALLVLPL
                     LPIIAIALLIKGRAARWPMSLLLWGCTFGHSEARLQTLQADFVRWFRDNVTAFPLVQE
                     RLTTYLLSSDADIWLITGSPQPLVEAVYFDTPWLPRVNLIASQIQRGYGGWVLTMRCL
                     GHEKVAQLERKIGTPLRLYSGYSDSNQDNPLLYFCQHRWRVTPRGELQQLE"
     gene            68466..69314
                     /locus_tag="RHX21_000330"
     CDS             68466..69314
                     /locus_tag="RHX21_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417056.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDV1985572.1"
                     /translation="MNGLLRIRQRYQGLAQSDKKLADYLLLQPDTARHLSSQQLANEA
                     GVSQSSVVKFAQKLGYKGFPALKLALSEALASQPESPSVPIHNQIRGDDPLRLVGEKL
                     IKENTAAMYATLNVNSEEKLHECVTMLRSARRIILTGIGASGLVAQNFAWKLMKIGFN
                     AAAVRDMHALLATVQASSPDDLLLAISYTGVRRELNLAADEMLRVGGKVLAITGFTPN
                     ALQQRASHCLYTIAEEQATNSASISACHAQGMLTDLLFIALIQQDLELAPERIRHSEA
                     LVKKLV"
     gene            69370..69630
                     /gene="yfhL"
                     /locus_tag="RHX21_000331"
     CDS             69370..69630
                     /gene="yfhL"
                     /locus_tag="RHX21_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster ferredoxin YfhL"
                     /protein_id="HDV1985573.1"
                     /translation="MALLITKKCINCDMCEPECPNEAISMGDHIYEINSDKCTECVGH
                     YETPTCQKVCPIPNTIVKDPAHVETEEQLWDKFVLMHHADKI"
     gene            complement(69824..69904)
                     /gene="shoB"
                     /locus_tag="RHX21_000332"
     CDS             complement(69824..69904)
                     /gene="shoB"
                     /locus_tag="RHX21_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin ShoB"
                     /protein_id="HDV1985574.1"
                     /translation="MTDCRYLIKRVIKIIIAVLQLILLFL"
     gene            complement(70324..70704)
                     /locus_tag="RHX21_000333"
     CDS             complement(70324..70704)
                     /locus_tag="RHX21_000333"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HDV1985575.1"
                     /translation="MAILGLGTDIVEIARIEAVIARSGERLARRVLSDNEWAIWKTHH
                     QPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALKLAEKL
                     GVVNMHVTLADERHYACATVIIES"
     gene            complement(70704..71435)
                     /gene="pdxJ"
                     /locus_tag="RHX21_000334"
     CDS             complement(70704..71435)
                     /gene="pdxJ"
                     /locus_tag="RHX21_000334"
                     /EC_number="2.6.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 5'-phosphate synthase"
                     /protein_id="HDV1985576.1"
                     /translation="MAELLLGVNIDHIATLRNARGTAYPDPVQAAFIAEQAGADGITV
                     HLREDRRHITDRDVRILRQTLDTRMNLEMAVTEEMLAIAVETKPHFCCLVPEKRQEVT
                     TEGGLDVAGQRDKMRDACKRLADAGIQVSLFIDADEEQIKAAAEVGAPFIEIHTGCYA
                     DAKTDAEQAQELARIAKAATFAASLGLKVNAGHGLTYHNVKAIAAIPEMHELNIGHAI
                     IGRAVMTGLKDAVAEMKRLMLEARG"
     gene            complement(71447..72175)
                     /gene="recO"
                     /locus_tag="RHX21_000335"
     CDS             complement(71447..72175)
                     /gene="recO"
                     /locus_tag="RHX21_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HDV1985577.1"
                     /translation="MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRS
                     TLKGALQPFTPLLLRFGGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEY
                     ETRFSELFFDYLHCIQSLAGATGTPEPALRRFELALLGHLGYGVNFTHCAGSGEPVDD
                     TMTYRYREEKGFIASVVIDNKTFTGRQLKALNAREFPDADTLRAAKRFTRMALKPYLG
                     GKPLKSRELFRQFMPKRTVKTHYE"
     gene            complement(72187..73092)
                     /gene="era"
                     /locus_tag="RHX21_000336"
     CDS             complement(72187..73092)
                     /gene="era"
                     /locus_tag="RHX21_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HDV1985578.1"
                     /translation="MSIDKSYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTR
                     HRIVGIHTEGAYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWT
                     PDDEMVLNKLRDGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGL
                     NVDTIAAIVRKHLPEATHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEI
                     ERFVSNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLE
                     LWVKVKSGWADDERALRSLGYVDDL"
     gene            complement(73089..73769)
                     /gene="rnc"
                     /locus_tag="RHX21_000337"
     CDS             complement(73089..73769)
                     /gene="rnc"
                     /locus_tag="RHX21_000337"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004248457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HDV1985579.1"
                     /translation="MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLG
                     DSILSYVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFELGECLRLGPGELK
                     SGGFRRESILADTVEALIGGVFLDSDIQTVEKLILNWYQTRLDEISPGDKQKDPKTRL
                     QEYLQGRHLPLPTYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQ
                     ALKKLELE"
     gene            complement(74042..75016)
                     /gene="lepB"
                     /locus_tag="RHX21_000338"
     CDS             complement(74042..75016)
                     /gene="lepB"
                     /locus_tag="RHX21_000338"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDV1985580.1"
                     /translation="MANMFALILVIATLVTGILWCVDKFFFAPKRRERQAAAQAAAGD
                     SLDKATLKKVAPKPGWLETGASVFPVLAIVLIVRSFIYEPFQIPSGSMMPTLLIGDFI
                     LVEKFAYGIKDPIYQKTLIETGHPKRGDIVVFKYPEDPKLDYIKRAVGLPGDKVTYDP
                     VSKELTIQPGCSSGQACENALPVTYSNVEPSDFVQTFSRRNGGEATSGFFEVPKNETK
                     ENGIRLSERKETLGDVTHRILTVPIAQDQVGMYYQQPGQQLATWIVPPGQYFMMGDNR
                     DNSADSRYWGFVPEANLVGRATAIWMSFDKQEGEWPTGVRLSRIGGIH"
     gene            complement(75032..76831)
                     /gene="lepA"
                     /locus_tag="RHX21_000339"
     CDS             complement(75032..76831)
                     /gene="lepA"
                     /locus_tag="RHX21_000339"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HDV1985581.1"
                     /translation="MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMEAQVLDSM
                     DLERERGITIKAQSVTLDYKASDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVV
                     DAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATDAVR
                     CSAKTGVGVQDVLERLVRDIPPPEGDPEGPLQALIIDSWFDNYLGVVSLIRIKNGTLR
                     KGDKVKVMSTGQTYNADRLGIFTPKQVDRTELKCGEVGWLVCAIKDIHGAPVGDTLTL
                     ARNPAEKALPGFKKVKPQVYAGLFPVSSDDYEAFRDALGKLSLNDASLFYEPESSSAL
                     GFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTSREVIYVDSPSKLPA
                     VNNIYELREPIAECHMLLPQAYLGNVITLCVEKRGVQTNMVYHGNQVALTYEIPMAEV
                     VLDFFDRLKSTSRGYASLDYNFKRFQASDMVRVDVLINGERVDALALITHRDNSQNRG
                     RELVEKMKDLIPRQQFDIAIQAAIGTHIIARSTVKQLRKNVLAKCYGGDISRKKKLLQ
                     KQKEGKKRMKQIGNVELPQEAFLAILHVGKDNK"
     gene            complement(77029..77508)
                     /gene="rseC"
                     /locus_tag="RHX21_000340"
     CDS             complement(77029..77508)
                     /gene="rseC"
                     /locus_tag="RHX21_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR-reducing system protein RseC"
                     /protein_id="HDV1985582.1"
                     /translation="MIKEWATVVSWQNGQALVSCDVKASCSSCASRAGCGSRVLNKLG
                     PQTTHTIVVPCDEPLVPGQKVELGIAEGSLLSSALLVYMSPLVGLFLIASLFQLLFAS
                     DVAALCGAVLGGIGGFLIARGYSRKFAARAEWQPIILSVALPPGLVRFETSSEDASQ"
     gene            complement(77505..78461)
                     /gene="rseB"
                     /locus_tag="RHX21_000341"
     CDS             complement(77505..78461)
                     /gene="rseB"
                     /locus_tag="RHX21_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E factor regulatory protein RseB"
                     /protein_id="HDV1985583.1"
                     /translation="MKQLWFAMSLVTGSLLFSANASATPASGALLQQMNLASQSLNYE
                     LSFISINKQGVESLRYRHARLDNRPLAQLLQMDGPRREVVQRGNEISYFEPGLEPFTL
                     NGDYIVDSLPSLIYTDFKRLSPYYDFISVGRTRIADRLCEVIRVVARDGTRYSYIVWM
                     DTESKLPMRVDLLDRDGETLEQFRVIAFNVNQDISSSMQTLAKANLPPLLSVPVGEKA
                     KFSWTPTWLPQGFSEVSSSRRPLPTMDNMPIESRLYSDGLFSFSVNVNRATPSSTDQM
                     LRTGRRTVSTSVRDNAEITIVGELPPQTAKRIAENIKFGAAQ"
     gene            complement(78461..79111)
                     /gene="rseA"
                     /locus_tag="RHX21_000342"
     CDS             complement(78461..79111)
                     /gene="rseA"
                     /locus_tag="RHX21_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma-E factor RseA"
                     /protein_id="HDV1985584.1"
                     /translation="MQKEQLSALMDGETLDSELLNELAHNPEMQKTWESYHLIRDSMR
                     GDTPEVLHFDISSRVMAAIEEEPVRQPATLIPEAQPAPHQWQKMPFWQKVRPWAAQLT
                     QMGVAACVSLAVIVGVQHYNGQSETSQQPETPVFNTLPMMGKASPVSLGVPSEATANN
                     GQQQQVQEQRRRINAMLQDYELQRRLHSEQLQFEQAQTQQAAVQVPGIQTLGTQSQ"
     gene            complement(79144..79719)
                     /gene="rpoE"
                     /locus_tag="RHX21_000343"
     CDS             complement(79144..79719)
                     /gene="rpoE"
                     /locus_tag="RHX21_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005070454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoE"
                     /protein_id="HDV1985585.1"
                     /translation="MSEQLTDQVLVERVQKGDQKAFNLLVVRYQHKVASLVSRYVPSG
                     DVPDVVQEAFIKAYRALDSFRGDSAFYTWLYRIAVNTAKNYLVAQGRRPPSSDVDAIE
                     AENFESGGALKEISNPENLMLSEELRQIVFRTIESLPEDLRMAITLRELDGLSYEEIA
                     AIMDCPVGTVRSRIFRAREAIDNKVQPLIRR"
     gene            complement(79716..79871)
                     /gene="rseD"
                     /locus_tag="RHX21_000344"
     CDS             complement(79716..79871)
                     /gene="rseD"
                     /locus_tag="RHX21_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rpoE leader peptide RseD"
                     /protein_id="HDV1985586.1"
                     /translation="MIRLQHDKQKQMRYGTLQKRDTLTLCLLKLQLMEWRFDSAWKFG
                     LGRLYLG"
     gene            80127..81749
                     /gene="nadB"
                     /locus_tag="RHX21_000345"
     CDS             80127..81749
                     /gene="nadB"
                     /locus_tag="RHX21_000345"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HDV1985587.1"
                     /translation="MNTLPEHSCDVLIIGSGAAGLSLALRLADQHQVIVLSKGPVTEG
                     STFYAQGGIAAVFDETDSIDSHVEDTLIAGAGICDRHAVEFVASNARSCVQWLIDQGV
                     LFDTHVQPNGEESYHLTREGGHSHRRILHAADATGREVQSTLVSKAQNHPNIRVLERS
                     NAVDLIVSDKIGLPGTRRVVGAWVWNRNKETVETCHAKAVVLATGGASKVYQYTTNPD
                     ISSGDGIAMAWRAGCRVANLELNQFHPTALYHPQARNFLLTEALRGEGAYLKRPDGTR
                     FMPDFDERGELAPRDIVARAIDHEMKRLGADCMFLDISHKPADFIRQHFPMIYEKLLG
                     LGIDLTQEPVPIVPAAHYTCGGVMVDDHGRTDVEGLYAIGEVSYTGLHGANRMASNSL
                     LECLVYGWSAAEDITRRMPDAHGVSTLPPWDESRVENPDERVVIQHNWHELRLFMWDY
                     VGIVRTTKRLERALRRITMLQQEIDEYYAHFRVSNNLLELRNLVQVAELIVRCAMMRK
                     ESRGLHFTLDYPELLTHSGPSILSPGNHYINR"
     gene            complement(81734..82471)
                     /gene="trmN"
                     /locus_tag="RHX21_000346"
     CDS             complement(81734..82471)
                     /gene="trmN"
                     /locus_tag="RHX21_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417070.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(1)(Val)
                     (adenine(37)-N(6))-methyltransferase TrmN"
                     /protein_id="HDV1985588.1"
                     /translation="MSQSTSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAG
                     VKRCLDIGAGSGLLALMLAQRTSDSVIIDAVELESEAAAQAQENINQSPWAERINVHT
                     ADIQQWITQQTVRFDLIISNPPYYQQGVECATPQREQARYTTTLDHPSLLTCAAECIT
                     EEGFFCVVLPEQIGNGFTELALSMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFS
                     DRLVIRGPDQNYSEAYTALTQAFYLFM"
     gene            82603..83937
                     /gene="srmB"
                     /locus_tag="RHX21_000347"
     CDS             82603..83937
                     /gene="srmB"
                     /locus_tag="RHX21_000347"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase SrmB"
                     /protein_id="HDV1985589.1"
                     /translation="MTVTTFSELELDESLLEALQDKGFTRPTAIQAAAIPPALDGRDV
                     LGSAPTGTGKTAAYLLPALQHLLDFPRKKSGPPRILILTPTRELAMQVADHARELAKH
                     THLDIATITGGVAYMNHAEVFSENQDIVVATTGRLLQYIKEENFDCRAVETLILDEAD
                     RMLDMGFAQDIEHIAGETRWRKQTLLFSATLEGDAIQDFAERLLEDPVEVSANPSTRE
                     RKKIHQWYYRADDLEHKTALLVHLLKQPEATRSIVFVRKRERVHELANWLREAGINNC
                     YLEGEMVQGKRNEAIKRLTEGRVNVLVATDVAARGIDIPDVSHVFNFDMPRSGDTYLH
                     RIGRTARAGRKGTAISLVEAHDHLLLGKVGRYIEEPIKARVIDELRPKTRAPSEKQTG
                     KPSKKVLAKRAEKKKAKEKEKPRVKKRHRDTKNIGKRRKPSGTGVPPQTTEE"
     gene            complement(84146..85027)
                     /locus_tag="RHX21_000348"
     CDS             complement(84146..85027)
                     /locus_tag="RHX21_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417072.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV1985590.1"
                     /translation="MDLRRFITLKTVVEEGSFLRASQKLCCTQSTVTFHIQQLEQEFS
                     VQLFEKIGRRMCLTREGKKLLPHIYELTRVMDTLREAAKKESDPDGELRVVSGETLLS
                     YRMPQVLQRFRQRAPKVRLSLQSLNCYVIRDALLNDEADVGVFYRVGNDDALNRRELG
                     EQSLVLVASPQIADVDFTEPGRHNACSFIINEPQCVFRQIFESTLRQRRITVENTIEL
                     LSIESIKRCVAANIGVSYLPRFAVEKELESGELIELPFGEQSQTITAMCAHHAGKAVS
                     PAMHTFIQCVEESFVAG"
     gene            85130..85717
                     /gene="eamB"
                     /locus_tag="RHX21_000349"
     CDS             85130..85717
                     /gene="eamB"
                     /locus_tag="RHX21_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/O-acetylserine transporter"
                     /protein_id="HDV1985591.1"
                     /translation="MTPTLLSAFWTYTLITAMTPGPNNILALSSATSHGFRQSTRVLA
                     GMSLGFLIVMLLCAGISFSLAVIDPAAVHLLSWAGAAYIVWLAWKIATSPTKEDGLQA
                     KPISFWASFALQFVNVKIILYGVTALSTFVLPQTQALSWVVGVSVLLAMIGTFGNVCW
                     ALAGHLFQRLFRQYGRQLNIVLALLLIYCAVRIFY"
     gene            complement(85772..86155)
                     /gene="grcA"
                     /locus_tag="RHX21_000350"
     CDS             complement(85772..86155)
                     /gene="grcA"
                     /locus_tag="RHX21_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007728348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autonomous glycyl radical cofactor GrcA"
                     /protein_id="HDV1985592.1"
                     /translation="MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKAGYAEDEVV
                     AVSKLGDIEYREVPVEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSG
                     YAVRFNSLTPEQQRDVIARTFTESL"
     gene            86460..87149
                     /gene="ung"
                     /locus_tag="RHX21_000351"
     CDS             86460..87149
                     /gene="ung"
                     /locus_tag="RHX21_000351"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDV1985593.1"
                     /translation="MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDV
                     FNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIATPPSLLNMYKELENTIPG
                     FTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVV
                     FLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGETPI
                     DWMPVLPAESE"
     gene            complement(87197..88234)
                     /locus_tag="RHX21_000352"
     CDS             complement(87197..88234)
                     /locus_tag="RHX21_000352"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA/rRNA methyltransferase"
                     /protein_id="HDV1985594.1"
                     /translation="MNDEMKGKSGKVKVMYVRSDDDSDKRTHNPRTGKGGGRPGKSRA
                     DGGRRPARDDKQSQPRDRKWEDSPWRTVSRAPGDETPEKADHGGISGKSYIDPEVLRR
                     QRAEETRVYGENACQALFQSRPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEA
                     ELTKASGTEHHGGVCFLIKKRNGTTVQQWVSQAGAQDCVLALENESNPHNLGGMMRSC
                     AHFGVKGVVVQDAALLESGAAIRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTTS
                     SEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGV
                     LLGEWWRQNKA"
     gene            88441..88860
                     /gene="trxC"
                     /locus_tag="RHX21_000353"
     CDS             88441..88860
                     /gene="trxC"
                     /locus_tag="RHX21_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxC"
                     /protein_id="HDV1985595.1"
                     /translation="MNTVCTHCQAINRIPDDRIEDAAKCGRCGHDLFDGEVINATGET
                     LDKLLKDDLPVVIDFWAPWCGPCRNFAPIFEDVAQERSGKVRFVKVNTEAERELSSRF
                     GIRSIPTIMIFKNGQVVDMLNGAVPKAPFDSWLNESL"
     gene            88929..89627
                     /gene="tapT"
                     /locus_tag="RHX21_000354"
                     /gene_synonym="tuaA"
                     /gene_synonym="yfiP"
     CDS             88929..89627
                     /gene="tapT"
                     /locus_tag="RHX21_000354"
                     /gene_synonym="tuaA"
                     /gene_synonym="yfiP"
                     /EC_number="2.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311476.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-uridine aminocarboxypropyltransferase"
                     /protein_id="HDV1985596.1"
                     /translation="MTENAVLQLRAERIARATRPFLARGNRVRRCQRCLLPEKLCLCS
                     TITPAQAKSRFCLLMFDTEPMKPSNTGRLIADILPDTVAFQWSRTEPSQDLLDLVQNP
                     DYQPMVVFPASYADEQREVIFTPPAGKPPLFIMLDGTWPEARKMFRKSPYLDNLPVIS
                     VDLSRLSAYRLREAQAEGQYCTAEVAIALLDMAGDTGAAAGLGEHFTRFKTRYLAGKT
                     QHLGSITAEQLESV"
     gene            89659..92319
                     /gene="pat"
                     /locus_tag="RHX21_000355"
     CDS             89659..92319
                     /gene="pat"
                     /locus_tag="RHX21_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein lysine acetyltransferase"
                     /protein_id="HDV1985597.1"
                     /translation="MSQRGLEALLRPKSIAVIGASMKPNRAGYLMMRNLLAGGFNGPV
                     LPVTPAWKAVLGVLAWPDIASLPFTPDLAVLCTNASRNLALLEELGEKGCKTCIILSA
                     PASQHEDLRACALRHNMRLLGPNSLGLLAPWQGLNASFSPVPIKRGKLAFISQSAAVS
                     NTILDWAQQREMGFSYFIALGDSLDIDVDELLDYLARDSKTSAILLYLEQLSDARRFV
                     SAARSASRNKPILVIKSGRSPAAQRLLNTTAGMDPAWDAAIQRAGLLRVQDTHELFSA
                     VETLSHMRPLRGDRLMIISNGAAPAALALDALWSHNGKLATLSEETCQKLRDALPGHV
                     AISNPLDLRDDASSEHYVKTLDILLHSQDFDALMVIHSPSAAAPATESAQELIEAVKH
                     HPRSKYVSLLTNWCGEHSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRNQKQLR
                     ETPALPSNLTSNTAEAHLLLQQAIAEGATSLDTHEVQPILQAYGMNTLPTWIASDSTE
                     AVHIAEQIGYPVALKLRSPDIPHKSEVQGVMLYLRTANEVQQAANAIFDRVKMAWPQA
                     RIHGLLVQSMANRAGAQELRVVVEHDPVFGPLIMLGEEGVEWRPEDQAVVALPPLNMN
                     LARYLVIQGIKSKKIRARSALRPLDVAGLSQLLVQVSNLIVDCPEIQRLDIHPLLASG
                     SEFTALDVTLDIAPFEGDNESRLAVRPYPHQLEEWVELKNGERCLFRPILPEDEPQLQ
                     QFISRVTKEDLYYRYFSEINEFTHEDLANMTQIDYDREMAFVAVRRIDQTEEILGVTR
                     AISDPDNIDAEFAVLVRSDLKGLGLGRRLMEKLITYTRDHGLQRLNGITMPNNRGMVA
                     LARKLGFNVDIQLEEGIVGLTLNLAQREES"
     gene            92433..93788
                     /gene="pssA"
                     /locus_tag="RHX21_000356"
     CDS             92433..93788
                     /gene="pssA"
                     /locus_tag="RHX21_000356"
                     /EC_number="2.7.8.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--serine
                     O-phosphatidyltransferase"
                     /protein_id="HDV1985598.1"
                     /translation="MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYAPADFRETLLEKI
                     ASAKQRICIVALYLEQDDGGKGILNALYEAKRQRPELDVRVLVDWHRAQRGRIGAAAS
                     NTNADWYCRMAQENPGVDVPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYL
                     HQHDKYRYDRYHLIRNRKMSDIMFEWVTQNIMNGRGVNRLDDVNRPKSPEIKNDIRLF
                     RQELRDAAYHFQGDADNDQLSVTPLVGLGKSSLLNKTIFHLMPCAEQKLTICTPYFNL
                     PAILVRNIIQLLREGKKVEIIVGDKTANDFYIPEDEPFKIIGALPYLYEINLRRFLSR
                     LQYYVNTDQLVVRLWKDDDNTYHLKGMWVDDKWMLITGNNLNPRAWRLDLENAILIHD
                     PQLELAPQREKELELIREHTTIVKHYRDLQSIADYPVKVRKLIRRLRRIRIDRLISRI
                     L"
     gene            93834..94157
                     /locus_tag="RHX21_000357"
     CDS             93834..94157
                     /locus_tag="RHX21_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417081.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfiM family lipoprotein"
                     /protein_id="HDV1985599.1"
                     /translation="MRILFVCSLLLLSGCSHMANDSWSGQDKAQHFIASAMLSAAGNE
                     YSQHQGMSRDRSAMFGLMFSVSLGASKELWDSRPEGSGWSWKDLAWDVAGASTGYTVW
                     QLTRH"
     gene            complement(94154..95452)
                     /gene="kgtP"
                     /locus_tag="RHX21_000358"
     CDS             complement(94154..95452)
                     /gene="kgtP"
                     /locus_tag="RHX21_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoglutarate permease"
                     /protein_id="HDV1985600.1"
                     /translation="MAESTVTADSKLTSSDTRRRIWAIVGASSGNLVEWFDFYVYSFC
                     SLYFAHIFFPSGNTTTQLLQTAGVFAAGFLMRPIGGWLFGRIADKHGRKKSMLLSVCM
                     MCFGSLVIACLPGYETIGTWAPALLLLARLFQGLSVGGEYGTSATYMSEVAVEGRKGF
                     YASFQYVTLIGGQLLALLVVVVLQHTMEDAALREWGWRIPFALGAVLAVVALWLRRQL
                     DETSQQETRALKEAGSLKGLWRNRRAFIMVLGFTAAGSLCFYTFTTYMQKYLVNTAGM
                     HANVASGIMTAALFVFMLIQPLIGALSDKIGRRTSMLCFGSLAAIFTVPILSALQNVS
                     SPYAAFGLVMCALLIVSFYTSISGILKAEMFPAQVRALGVGLSYAVANAIFGGSAEYV
                     ALSLKSIGMETAFFWYVTLMAVVAFLVSLMLHRKGKGMRL"
BASE COUNT        22831 a        26103 c        24076 g        22754 t
ORIGIN      
        1 aaatttaatc tatcccttta tacgcaatac atttactttc ctcttttgat gatcttaaat
       61 gtcttatttt tcgtaatgtg tataacaagg aatagtgatg aaatttaaaa aatgtcttct
      121 gcctgtggca atgttagcgt cattcactct ggcaggatgc cagtcaaatg ctgacgatca
      181 tgccgccgat gtttatcaaa ccgatcaact gaataccaaa caagaaacta aaaccgttaa
      241 tattatttcc attcttcccg caaaagttgc cgtagacaac tcccaaaata aacggaacgc
      301 acaagccttc ggcgcgctta ttggcgcagt cgctggcggt gttatcggcc acaacgtcgg
      361 ttctggcagc aattccggaa cgacggcagg ggcagttggc ggcggagctg taggcgcggc
      421 agtgggttct atggtgaatg ataaaacctt agtggaaggt gtttctttaa catataagga
      481 aggcaccaaa gtgtatacct ctacccaggt gggtaaagag tgccagttta cgacaggttt
      541 agccgttgtt attaccacaa cgtataacga aacgcgtatt cagccaaata ctaaatgtcc
      601 tgaaaagagc taataatcag gaggagtcat gaagaaagtt tttctttgcg ccatcttagc
      661 ctccttaagc tatccggcta tcgcctcatc attgcaggat caactctctg ctgtcgcaga
      721 agcggaacag caaggtaaaa atgaagagca aaggcagcat gacgaatggg tcgcggagcg
      781 caacagggaa atccagcaag agaagcaacg tcgcgcaaat gcccaggccg ccgctaacaa
      841 aagagcggca acggcagcgg caaataagaa agctcgtcag gataaactgg acgccgaagc
      901 cactgcggac aaaaaacgcg atcaaagtta tgaagatgag ctacgcagct tagagattca
      961 gaaacaaaaa ctggcgctgg cgaaagaaga agcccgcgtt aagcgcgaaa acgaatttat
     1021 cgatcaggaa ctgaagcaca aagctgcgca aaccgatgtg gtgcaatctg aagctgacgc
     1081 caacagaaat atgactgaag gcggtcgcga tctgatgaaa agcgtgggca aagcagaaga
     1141 gaacaaatcg gaaagctggt ttaattaatc gatgttagta acttcaagcc tatgattctt
     1201 gaagataaaa aaccctctgt agtaacagag ggttttgttc attcatagtg cagggtcaaa
     1261 tcattcccac tcaatggtag ctggcggctt gccgctgatg tcatacacca cgcgagaaat
     1321 accgttcact tcattgataa tgcggttgga aacacgaccg aggaaatcgt acggcagatg
     1381 cgcccagtgt gcggtcataa agtcgatggt ttcgacagca cgcagagaga caacccagtc
     1441 atacttacga ccatcgccca ttacgccaac ggaacgtacc ggcaggaaca cagtgaacgc
     1501 ctggctgact ttgtcgtaca ggtccgcttt acgcagttct tcaatgaaga tggcgtcagc
     1561 acggcgcagc aggtcacagt actctttctt cacttcaccc agcacacgaa cgccaaggcc
     1621 tggtcccggg aacgggtgac ggtacagcat gtcgtacggc aggcccagct ccagaccaat
     1681 cttacgcact tcgtctttga acagctcttt cagcggttca accaggccca tcttcatctc
     1741 tttcggcagg ccgcccacgt tgtggtgaga tttgatgacg tgtgctttac cggttgcaga
     1801 agccgcagat tcgataacgt cagggtagat ggtgccctgc gccagccact tcacgtcttc
     1861 cagtttcagc gcttcttcat cgaacacttc aacgaaaacg cgcccgatga ttttacgttt
     1921 tgcttccgga tcgttttcgc cagccagcgc tgacaggaag cgatcttctg ccggtacgtg
     1981 aacaatgttc agaccaaagt gatcgccaaa catatccaga acctgctctg cttcgttgag
     2041 acgcagcagg ccgttgtcga cgaatacgca agtcaggttt ttaccgatag cgcggtgcag
     2101 cagcattgcg gttacggagg aatccacacc accagagagg ccgaggatga ctttatcgtc
     2161 gcctacctgc tcgcggatgc gagctacagc atcgtcgata attttcgctg gcgtccacag
     2221 ggcttcacac tggcagatat cacgcacaaa acgctccagc atgcgcatac cctggcgggt
     2281 gtgagtcact tccgggtgga actgtacgcc atagaagcgt ttttcttcgt tagccataat
     2341 ggcaaacggg cagctttcgg tgctggctac ggtgacgaag tcggacggga tagcggtaac
     2401 tttatcgccg tggctcatcc agacatcgag cagcggttta ccgtctgcgg tcagcgcatc
     2461 ttcgataccg cgaaccagtg cgctgtcgtt tacgacttca acctgcgcgt agccaaattc
     2521 acgttcgtta gaggcttcaa cgtgaccgcc caactgcatt gccatggtct gcatgccata
     2581 gcaaacgccg aataccggta cgcctgcttc aaagacatac tgcggcgcac gcgggctgtt
     2641 ttcttcggtg gtgctttccg ggccgccgga aagaataatg ccgcttggat tgaagtcacg
     2701 aatttgtgct tctgtcacat cccacgccca cagttcgcag taaacaccca gctcacgcac
     2761 gcggcgcgca accagttgag tgtactgaga accgaagtcc agaatgagga tgcgatgctt
     2821 atgaatgttt tccgtcattg acgcttattc cgaggcaagt gaaacagata atataaatcg
     2881 cccgacatga agtcgggcga agagaatcag gagcccagac ggtagttcgg ggactcttta
     2941 gtaatggtca cgtcgtgaac gtggctttcc tgaatgcccg caccgctgat acgtacaaac
     3001 tccgctttag tacgcagttc gtcgatagta ccacagccgg tcagacccat acaggagcgc
     3061 aggccgccca tctgctggtg aatgatctct ttcaggcgac ctttataagc tacgcgacct
     3121 tcgatacctt ccggcaccag tttgtcggca gcgttatcgc tctggaaata acggtcagag
     3181 gaacctttgg acatcgcgcc cagggaaccc ataccacggt aagatttgta agaacggccc
     3241 tggtagagtt cgatttcacc cggagattct tcagtacccg ccagcatgga acctaccatc
     3301 accgcgcttg cgccagcggc gatagctttg gcgatgtcgc cggagaagcg aataccacca
     3361 tctgcgataa ccggaatacc ggtgccttcc agggcttcaa ctgcgtcagc aacggcagtg
     3421 atctgcggaa cacctacgcc agtaacgata cgagtcgtac agatagaacc agggccgata
     3481 ccgactttaa ccgcgctgca accagcttct gccaaagcgc gtgcacctgc agctgttgcc
     3541 acgttgccgc cgatgatttg cagatccgga tatttagcac gggtttcacg gatacgctgc
     3601 aaaacgcctt ctgagtgacc gtgggaggag tcaatcagca gaacgtcaac gccagcggca
     3661 accagcgcgt caacacgctc ttcgttaccc gcacctgcgc caactgcagc accaacacgc
     3721 agacggcctt gctcgtcttt acaggcgttc ggtttacgtt ccgctttctg gaagtctttc
     3781 acggtgatca tgccgatcag gtggaattcg tcatcaacca ccagcgcttt ttcaacgcgt
     3841 ttttcgtgca tttttgccag caccacttca cgggcttcac cttcacgcac ggtgaccaga
     3901 cgctctttcg gcgtcatgta aacgctaacc ggctggttca ggtcggtaac aaaacgcacg
     3961 tcacgaccgg tgataatacc caccagttcg ttttcttcgg taacgaccgg atagcccgca
     4021 aaaccgttac gctcagtcag ttctttcact tcgcgcagcg tcgtggttgg cagaacagtc
     4081 tgcggatcag tcaccacacc agattcgtgt tttttcacac ggcgaacttc ttctgcctgg
     4141 cgttcaatgg acatgttttt gtggataaag ccgataccgc cttcctgagc cagagcaata
     4201 gccaggcgcg cttccgttac ggtatccatt gctgcggaaa gcatagggat attcagacga
     4261 atagttttcg tcagctgggt gctgaggtca gcagtattcg gcagaacggt agaatgagca
     4321 ggaacgagga gaacgtcgtc aaacgtcaga gcttctttag cgatacgtag catgggcaat
     4381 atctcgacca gagtggttaa taaatattgc cgcggcatta tacagagcgt aaccgattgc
     4441 atctacccct ttttgcaaaa aatgcttgct atccccgaag ggcgggttac tatcgactga
     4501 ataacctgct gatttagaat ttgatctcgc tcacatgtta ccttctcaat cccctgcaat
     4561 ttttaccgtt agtcgcctga atcaaacggt tcgtctgctg cttgagcatg agatgggaca
     4621 ggtttggatc agcggcgaaa tctctaattt cacacaaccg gcttccggtc actggtactt
     4681 tacactcaaa gacgacaccg cccaggtacg ctgcgcgatg ttccgcaaca gcaaccgccg
     4741 ggtgaccttc cgtccacagc atggacaaca agttttagtt cgcgccaata ttacgctcta
     4801 cgagccgcgc ggtgactacc agataatcgt tgagagtatg cagccggccg gtgaagggct
     4861 gctgcaacag aagtacgaac agctcaaagc gaagttgcag gctgaaggtt tgttcgatca
     4921 gcaatacaaa aaaccacttc cctcccctgc gcattgcgtt ggtgtgatca cctcaaaaac
     4981 cggtgctgcg ctacatgata ttttgcatgt gttaaaacgt cgcgatcctt ctctaccggt
     5041 gatcatctac cccaccgccg ttcagggcga tgacgcaccg gggcaaattg ttcgcgccat
     5101 tgaactggcg aatcagcgca atgagtgcga cgtgttgatc gttgggcgcg gcggcggttc
     5161 gctggaagat ttatggagtt ttaacgacga acgcgtagcg cgggcgattt ttgccagccg
     5221 cattccggtc gtcagcgccg tcgggcatga gacggatgtg accattgccg attttgttgc
     5281 cgatctgcgt gcgccaacgc cgtctgccgc cgctgaagta gtgagccgta atcagcaaga
     5341 gttactgcgc caggtgcaat cgacccgtca acggctggag atggcgatgg attattatct
     5401 cgccaaccgc acgcgtcgct ttacgcagat ccatcaccga ttacagcaac agcatccgca
     5461 gctccggctg gcacgccagc aaaccatgct tgagcgcctg caaaagcgga tgagctttgc
     5521 gctggaaaat caacttaagc gtaccgggca acagcagcag cggttaacac agcggctgaa
     5581 tcagcaaaat ccacagccga agattcatcg cgcgcaaacg cgcattcagc aactggaata
     5641 tcgtttagca gaaaccctgc gcgtacagct tagcgccacg cgtgaacgtt tcggtaatgc
     5701 agtaacgcac ctcgaagccg taagcccact gtcaacgctg gcgcgtggat acagcgttac
     5761 tactgctact gacggcaatg tactgaaaaa agtgaagcaa gttaaagcgg gtgaaatgct
     5821 aaccacacgt ctggaagacg gctggataga aagtgaagtt aaaaacatcc agccagtaaa
     5881 aaaatcgcgt aaaaaggtgc attaagccag cacgaattca acgcgttttt tcgatatcaa
     5941 gccatgcccg tgctgacaga agtaatctac tgcaccgcag gcttttaaca cctgcaacgg
     6001 ttgatggcag tctggacaaa gagctttcat ttcaataatt tccccgcagg atgggcaacg
     6061 cgcatggccg ttatcctgat caagcacatg ctgacattgt ggacaatgca gttccatatg
     6121 aattcctccg gtagccatcc ctctacattc atagagggaa tggcagataa aatacttacg
     6181 gataattatt tatttttctt gatgtgcttc atcagacgct tacgtttacg catctgggtt
     6241 ggcgtcaggg tgttacgctt gttcgcatac gggttttccc cttctttgaa ctgaatacga
     6301 atcggcgatc ccattacgtc cagcgatttg cggaagtagt tcatcaagta gcgcttgtag
     6361 gaatcaggca ggtctttcac ctgattaccg tgaatcacca caatcggcgg gttataacca
     6421 ccagcgtggg catatttcag cttcacacga cgaccgcgta ccagcggcgg ttggtgatct
     6481 tcaacagcca tcgtcatgat gcgcgtcagc atagaggtcc ccacacgacg ggtggagctg
     6541 tcatacgctt cacgtactga ttcaaacaag ttaccaacac cactgccgtg caaggcagag
     6601 ataaagtgca cacgagcaaa atcgataaag cccagacgga agtccagcgt ttctttcacc
     6661 tgctctttca cttcctggct caggccatcc cacttattca ccacaatgac aagtgagcgc
     6721 ccactattga gaataaagcc cagcagcgag agatcctgat cggaaatacc ttcgcgcgca
     6781 tcaatcacta acatcaccac gttggcatct tcaatggcct gcaacgtttt gattacggag
     6841 aatttctcta cagcatcggt gattttgccg cgtttacgta cgccagcggt atcaatgagc
     6901 acatactcac gtccatcgcg ttccattgga atgtagatac tgtcacgcgt cgtgccaggc
     6961 atgtcataaa caacaacgcg ctcttcacca agaatacggt tagtgagtgt agacttacct
     7021 acgttcggac gacccacaat cgccagtttg atcggcagac tttgcgggtc gaagtcgtct
     7081 tcctcttctt cttcgccgtt ctcttccgct tcaaattgcg cccagtattc agcgtcttcg
     7141 tcgacttcct cttgcggtgc gagatcttcc atccacggca gcagcacatg ctccagcaga
     7201 cttaatacgc cacgaccgtg agacgcggcg atcgggtaga tttcacctaa accaagcgag
     7261 tagaaatcaa ccactgcctg atcgggatcc agaccgtcag ttttgtttgc caccaggaag
     7321 gtcggttttt cacgggagcg cagatgtttg gcaatcgctt catctgccgg catcaggccc
     7381 gcgcgcgcat ccaccataaa cagtacgacg tccgcttctt caatcgccag cagcgactgt
     7441 tccgccatgc gggtttctac accgtcttct gtgccatcaa tcccgccggt atcaatacag
     7501 ataaactcac ggccttcaat ttccgcacga ccgtacttac ggtcacgagt cagacccggg
     7561 aaatccgcaa ccagcgcatc tcgggtgcga gttagacggt taaataacgt ggattttcct
     7621 acgttagggc gcccgacaag cgcgaccaca ggtaccatgt ttaaagcctc atttttataa
     7681 atcatcagac aacgcacgct atattcgcgt cgttgttaaa aacaggaaaa cggcccctgt
     7741 ccaggagccg ttttcaaagt gaacgacaga gacgattaac gtgtaataga gtacacggtt
     7801 ccgtcttttg cctggatcag cagtttgccg tcagcggcaa ccggttcagt ctggaaaccg
     7861 gaactatcaa ctttttgctg ggcaacgaaa cgaccatctt cgacgttaat ccagtgcaga
     7921 taaccttcac tgtcaccgac caccaggttg ccattataca gcaccggaga agtcagcagg
     7981 cgatgcagca gatcgctttg tgcccacagc gtaacgccgc catcaatggt caacgccatc
     8041 acccggtcat tttgatcgac cagatagatg cgattgccgt cgacgatgaa atcattcacc
     8101 gaacccagtt cgcgtttcca cataatctga ccactgcgca gatcaagcgc cgtcaggtta
     8161 ccattatagg ccagcgcgaa aacaacgccg ttaacaacga cgggagtcgt gtcaacatcg
     8221 ctcagacggt caatttcggt agaaccggtc gcctgggaaa tacgctgctg ccaaatcatc
     8281 tggccctgtt ccatcagcac tgcgctgacg cgaccattat cgccccccac gacggccgca
     8341 ccaaaagccg ttgccggcgc agactcgcca cgcaaagaga gcgaaggcat atcgaggtta
     8401 actgtccatt tgacagcgcc gtcagcttcg ttcagcgctt gtaactgacc gttactggtg
     8461 tggattaaca ccagaccgtc gctgaccacc gggcgcgaaa gtgcttcacc cgcgacttta
     8521 gtttgccatg ccacagtacc atcgctggta ttcagcgcgt aaacctgcgc cttttcgctg
     8581 ccaatgtaga catgcccacc agacacggtc acaccgccag aaagtaatgc aggctcttta
     8641 gagaaccagc catctttctc ggccaggctg acagaccaga tttctttgcc atcatccgca
     8701 ttcagcgctt ttaccaaacc agcgcggtcc gctgcataga caacgttgtc cgccagtgcc
     8761 ggatgaagat tggaatagaa gttgccaatg ccgctaccaa cggaagtact ccacgccgtg
     8821 gtcggcgtaa actggttttc aacggttggc aatggggaca tctttaccac atcttcttcg
     8881 ctgttaaaca gcgaacagcc gcttaaaagg gtaacggaaa gcagtcctgg cagcagtaat
     8941 ttacgcaatt gcatcgggtc cctctcagat ggacaaatta ttaattttca tctgcatcat
     9001 ttcgctcagt gccggagtaa catcgctttt cacgcctgct tcccatgcac tacgcgcacc
     9061 ttgcttatca cctttgctca gcaatgcttc accacgcagg tcggcaacaa tggcagccca
     9121 cccttcacct ttgatggtat caagggtttt cagcgcggca tcagcctgct tgagctgtac
     9181 ctgaacgcga gcaagacgca gatttatcac ggctttgaga ttttcatcgc tcgtgtctgc
     9241 cagcccctgt tgtaactggg cggcagcttt ctctagttca tttttgtcaa caaattgctg
     9301 cgcaagttcc aaagaagcca gcgcaccata agtattttta ttttcagcag caaatttttc
     9361 cgccgccggg atgctatccg gtttgccttc gctcactgcg gtaaccgcat tttgataggc
     9421 aagagaagcg gagcgtgcag aatcaacctg atggctgttc cagtagcgcc agccaatcag
     9481 tgcgccaacg cccaaaatca ccccaacagc cagtgctttg ccattttcag caaaaaagcg
     9541 tttaaccgct tctacctggt cgttttcgtt ctcgtaaatt tccacgctgt ccttctcctt
     9601 ccttaaccca gtaacgtgcg caaatgcgcg gctacgctat cctgcgcaac tgccgtttgc
     9661 tcaccagagc gcaaatcctt cactactgct gtgccgttag ccacttcaga ctcacccagc
     9721 accacagcaa cgcgggcacc ccatttatca gcacgggcaa actgtttctt aaagttgccg
     9781 ccgccgtggt tggtcatcaa tttcacgccc ggtaattcat cacgcagacg ctcagctaat
     9841 gccatagccg cagattgtgt atcagcacct gaagccacca ggtatatatc gacaacagga
     9901 tcggctttaa attccggatt aacggcctgt actaacaata caagacgttc gaggcccatc
     9961 gcaaaaccga cagccggtgt tgcacgaccg cccagttgtt ccacaagacc gtcataacga
    10021 ccgcctgcac acacggtgcc ctgggagccg agactgttag tcacccactc gaaaacggta
    10081 cggttatagt aatccagacc acgcaccaga cgctggttta cggtgtaagc gatccccgcg
    10141 ctctcaagca gtttgcacag accggcaaaa tgctcacgag attcctcgtc cagataatca
    10201 cctaatgccg gagcgtcgtt gagaagcgcc tgcacttccg gattttttga atccagcacg
    10261 cgcagcgggt tagtgtacat gcggcgtttg cagtcttcgt ccagcttatc tttatactgc
    10321 tcaaggaatg ccaccagcgc atcgcggtaa ttggcgcgtg cttccagcga accgatagag
    10381 ttcagctcaa gagttacgtg ctcggaaata cccagcgcac gccaccagcg ggcggtgagc
    10441 ataatcagtt cagcgtcgat atccggacct tgcagaccga aaacttcgca gcccaactga
    10501 tggaactgac gataacgccc tttctgcgga cgctcgtgac ggaacatcgg cccgatatac
    10561 cacagacgct gttcctgatt gtacagaaga ccatgctcga tgccggcgcg tacacagccc
    10621 gccgtccctt cagggcgcag agtcaggctg tcgccattgc gatcctcaaa ggtgtacatc
    10681 tctttttcaa ccacgtcggt gacttcacca atcgcacgtt tgaatagcgg ggtctgctct
    10741 acaatcggca agcggatttc actgtaaccg tagctgccga gcacgttttt cagtgtgcct
    10801 tcaatgcgct gccagatggc cgtttcgcca ggcaggtaat cgttcatgcc gcgaatggct
    10861 tgaatgtttt ttgccacgtt tattctcttt ctgaatataa aaatgaaccc tcaacgcttc
    10921 cctcaatgtt tcgggagcta tgcgggttca atcatacacg ggaagcgagg cgcttcccat
    10981 cacgttatta tttttcaacc tgctgaacgt caattcgacg cgcttcgtcc agctgactgg
    11041 ctttcgcacg aatgcgtgct tccaactggt cgatcatatc gttgttgtcc agacggtctt
    11101 tgcgcacgcc atcttcatag aggccgcttt tcttgttgcc gccggtgacg ccgagtgtag
    11161 aaaccagcgc ctcacctggg ccattcacca cgcagccgat aatcgaaacg tccatcggag
    11221 tgatgatatc ttccaggcgt tgctccagcg cgttaaccgt accgataaca tcaaattcct
    11281 gacgcgaaca ggtcgggcag gcgatgaagt tgatcccgcg cgaacggata cgcagcgatt
    11341 tcaaaatatc gaaaccgact ttgatctctt cgaccggatc ggccgccagt gatacgcgca
    11401 gcgtgtcgcc gatgccttca gacagcagca gacctaaacc aatggcggat tttactgccc
    11461 cgctgcgtgc accaccggct tcggtgatcc ccagatgcag cggctgatcg atctgttttg
    11521 ccagcaaacg ataagactca acagcgagga agacgtcaga cgctttcacg ctgactttga
    11581 actgatcgaa gttcaggcga tcgagatgat caacatggcg catggcggat tccagcaacg
    11641 cctgcggcgt cggttcgcca tacttttctt gcagatcttt ttccagcgat ccggcgttaa
    11701 cgccaatacg gatcggaatg tttttatcgc gcgcacagtc aaccaccatg cgaatacgct
    11761 cttcattacc gatattgcca gggttaatac gcagacaatc gacgccgtat tccgctactt
    11821 tcagtgcaat gcgatagtcg aagtggatgt cagccaccag cggcacgtta acctgctgtt
    11881 tgatgagttt gaacgcttct gccgcgtcca tcgtcggtac ggagacacgg acgatatcag
    11941 cgccaacgcg ttccagcgcc ttgatttgat tgaccgttgc ttcgacgtct gtcgtacgcg
    12001 tattggtcat ggactgtacg gcgatgggag caccatcgcc aatcggcaca ttcccaacgt
    12061 aaatacgtgt tgattttcta cgttgaattg gagcctggtt atgcatgaaa aatctcccgc
    12121 gttacccgtc tgttactgcg ccggtgattg ttcggcattg agggtcagac gcgcaacctg
    12181 gttagttctg ataaaacgac tcagatcgac aggtttccct tgatactgga tctgtactgc
    12241 ggctggcgca ccaattttca gtttgtatgg tgcctggccg gttaagttca aattaccgtc
    12301 tttacgctgc ataccgctaa acaatttttt accggtagca tcagtaacct ccagccagca
    12361 atcggcagta aagttcatca ccagcgcatt cggatcagcc gccggcgtag tcacgcctgc
    12421 ctgatcggtt ggcaacggcg cagcgccatc tggcgttgtt gttgccgttg gtgccggggt
    12481 cgcggcggta tcaacatttg cctgcgaagg cgaaacaacc gcattctgtt gcggatcaac
    12541 agctggtgct ggcgcagtta cggcaggtgt ttgcgtgttg gttgcggtag tatccacaga
    12601 cgctggcggc gtggacgttg tagccgggtc tgtagttgtc gacgtattta acggaacact
    12661 ctgcccctgc tcgctattac tgctcagttc cgccgaagat tgatcggcca tagtggtgat
    12721 ctcttcctgc tgagctttgt ggtcttgcca ccaccaggca ccgctcaggc cgataaccac
    12781 aaacaacacc agccaggtga aggtcatcag ccagccgtca cgttttttgc ggcgtttacc
    12841 gagggaaaaa ctctgcatag gcgcaacttt tgcagcccgt agtggagcct gcttttccag
    12901 ccctggcagc agttcttctt ctggaatatg taccagacgc gcataagagc ggatatatcc
    12961 gcgcaggaat gttgaagcaa gatcggcggg tgccttatct tcttcaatgt cgcgtaccgt
    13021 ggaaaccttc aggcaaagtc gctcggcaac ggcctgctga ctaagtccta gttgttcgcg
    13081 agcattacgc aggcgagcgc cggtagtaag tgcttcattt tggtcgtgcg tggcttcagt
    13141 attcattcgc tgcaggtacg tttaaatgag aattgagatg ccggtgaacc atcatgctca
    13201 cccacaccgc gaaacatccg ttaagttaac cgttatcata cagtataaga ccgtctgtgt
    13261 gctcgtgaca aagcccacat tcactaaggc taacttactg ttgcatcgtt acatactgcc
    13321 ttaaagtcag caaaaacgca ccgttaatat tgaccagaca attgcaactt aatacttcat
    13381 tcataaaaga ttacgccacg gtacataaag taaccgtggc gtaatggcta tcagaccgct
    13441 ttaatgtcga tggcttcacc ctgcatccgt ttacgcaggg tacgtttcgt acggtcgata
    13501 acatcgcccg ccaactgacc acaggcagca tcgatatcat caccacgggt tttacgcaca
    13561 atagtggtga aaccgtagct catcagcact tttgagaaac ggtcgatacg gctgttcgag
    13621 ctgcgtccat acggcgcgcc cgggaagggg ttccacggga tcaggttgat cttacacggc
    13681 gtatctttca gcagttccgc cagttggtgc gcgtgttcag tgccgtcgtt aacgtggtca
    13741 agcatcacat actcaatagt gacacggccc tgattggcgt tggatttctc cagataacgg
    13801 cgcaccgcag caaggaacgt ttcgatattg tactttttgt tgatcggcac aatttcgtca
    13861 cgaatttcgt cgttcggcgc gtgcagggaa attgccagtg caacgtcgat catatcgccc
    13921 agtttatcca gcgccggaac tacaccggaa gtagaaagcg tgacgcgacg tttagacagg
    13981 ccaaaaccga aatcatcaag catgatttcc atcgccggaa cgacgttgtt caggttgagc
    14041 agcggctcgc ccatgcccat catcactacg ttagtgattg ggcgctgacc ggtgactttt
    14101 gctgcgccga cgattttcgc cgcacgccac acctggccaa taatttccga tacccgcagg
    14161 ttgcggttaa agccctgctg ggcggtggaa cagaatttac actccagcgc acaccccacc
    14221 tgcgaagaga cgcagagcgt ggcacggtcg tcttccggga tatacaccgt ttcgacgcgc
    14281 tgatcgccaa cggcgatcgc ccatttaatg gtgccgtcgg atgaacgctg ttcttcaacc
    14341 acttccggtg cgcggatttc cgccacctct ttcagtttgc cgcgcaacac tttgttgatg
    14401 tcggtcatct catcaaagtt gtcgcagcaa tagtgataca tccacttcat cacctgatcg
    14461 gcgcggaagg gtttttcacc taaatcttta aaaaactccc gcatctgctg acggttgaga
    14521 tccagcaggt tgatttttcc atctttcgtg gtgacgtttt caggtgtgac taattgttca
    14581 gacatatgct attccggcct cgttattaca cgttatggcc cctggaggat tgaaaaaaga
    14641 aacgccccgg tgagcggctg ctcgtccggg ggcgctgcat tgtacaaatt ctggcgcacg
    14701 gatgccacgt ttgcacgcgg catttacgaa attattaacg ggtgcgcggg cacacttcgc
    14761 cttcgccaaa gaaataagcg atttcgcgag cggcagattc gacggaatca gaaccgtggg
    14821 taccgttttc ggtcaggctg tcagcgtaat cagcgcgcag agtaccagcc agtgcgtttg
    14881 ccggattggt cgcgcccagc agatcgcggt gacgctgaac ggcgttttca ccttccagca
    14941 cggaaaccac gatcgggcca gaggtcatga attcaaccag accatcaaag aacggttttc
    15001 catcgtgttc agcataaaag ccacgtgcct gttcaacggt caggtgcagc attttggtgc
    15061 cgacaatttt gaaccctgca gcttcaaagc gcgcaaagat attaccaatg acgttttttg
    15121 ctaccgcgtt cggtttgatg atggaaaaag tacgttcaat agccattttt acctctgtaa
    15181 attgttctgt tgttgtctgt accagcgtac gagatggcgc ggattataat gagcaacagg
    15241 gccgttgact attgatgaag gtaacatttt tttaaaataa aatgagtttt agcaacaatc
    15301 agggacaaaa cagactattg catgacaaat ttcactgtcg cgatttgccc cacatcatcc
    15361 atcaccagca attgataatc acctttatcc gtcaaatgca gggtcacgtt gcgcccgcgt
    15421 tcagttaacg gttcgccatt cagaaaccac cagcgttcac ctgcccctcc acttgattgc
    15481 aacggcaaag tcgcttccgc tgcgcccggt aaacgtttaa taatcgcgcc atcgcgaacg
    15541 cctgtcagct gcagagggag ctgggcatcg tgaccgtatg acgggcaaat tgtcgaggcc
    15601 ggtggtaagc gcacagcgcg acgttctgat gcgggcagcc agggttccag cggtagcggc
    15661 cagacattta tcatttcttg tcgcgcttgc gggcaatcag cggcaacacg tttgccattt
    15721 tcatccagcc agatggggaa acgaatgcca ttaatgcctt cctgctccgg cagtaataga
    15781 gttggcggct gactcccgtc cagcagccag gttgccaggc ggcggcgaca gttaccgtca
    15841 ccttccggca aagactgtcc gcccggccag cagataacgc cacgagtgac tgagttcggg
    15901 cgcgggtctt ccggcagatt cgcactgcgc gacagtaaga tattattgac ctgattcaac
    15961 aatggtacgg cactggcaaa gccaaactga ccaacaacgg gcgtgccgtc cggtctgcca
    16021 gtccagatcc caatgacata gcgagcgtta accccaatcg cccaggcgtc acgatagcca
    16081 tagctggtgc ccgttttcca tgccagtggg gcgacgcgcg gcaaggcact atccggcaag
    16141 ggtttcgctt catcagccat aatccggcga atgatccacg ccgcccccga cgacattaaa
    16201 ggccgttcaa gcagcggatc gtcaggctgt aagcgcaatt tgcctgcctt gccgtggcga
    16261 gcaaacgcgg tatacgctgc cgccatatct tccagttttg caccagcgcc gccgagaatg
    16321 agtgaaagat tcggcgcagc accgttgggc aaatataacg gcaatccaac attgcgtaac
    16381 tttgccgcaa accgtttcgg tccataggct tccagcacct gcacagcagg taagttcagc
    16441 gagcgcacca gcgcctcgct catgctgatc gggccatgaa aaccgctatc aaagttacct
    16501 ggtcgataat caccggtgcg ccgggggacg tcttgcagca gtgatgccgg gtggatcaag
    16561 ccttcatcca gcgccagacc ataaacaaac ggtttgagca ccgatcctgg cgatcggatc
    16621 gcattgacca tatcaacatg accaaagcgt gaatcatcgt tgagatcaac cgatcccacc
    16681 cagccgcgaa cacgcatatc ggtatgatca accacgatca tcgccagtga gctgcgcggt
    16741 ggcaaccgac ctttccagtt ttgcgccagt tcttccagac gtcgttgaag accggcatcc
    16801 agcgtagtaa cgattttgtc gcttttgctt ttaccgagca tcatgcgcga aaacagcggt
    16861 gccagttgcg gcatttgtcg gggtgccagc cagatgggtt cttcccttga ctcttttacc
    16921 tgctcacggg accacgcacc ttgcacggcc atccgttcga gcactttatt acgcgcggct
    16981 tcggcacgct ccggccaacg atccgggcga agacggctgg gcgcttgcgg caaaaccgcc
    17041 agcattgccg cctcggaata gcttaaattc gcaggcgact ttccgagata agcccaactt
    17101 gccgcaccga tcccctgcaa cgtaccgcca aacggagcgc ggttaagata caaggtcaga
    17161 atttcacgct tagacagatg ccattccagt tgcaacgcgc gccagagctg gcgaattttg
    17221 ccgccaaatg ttttggggtg aggatcaagc agacgagcaa cctgcatagt gagcgtgctg
    17281 ccaccggaaa taacccgtcc cgaagtgaga tcttgccatg ctgcgcgcgc caccgagaat
    17341 ggattcaccc ccggatgctt ccagaaccag cgatcttcat aattgatcag cgcttcaagg
    17401 taacgtggag aaacatcttc gattgttacc ggataacgcc agatgccgtc agcatcggcg
    17461 aagcgccata gcggcgtacc atcctgcgcc acgaccactc gtgcgggatt gacttcatgc
    17521 agcggtagag gccagagttt atctgctccc cacgctgcaa gaaaaaggag aaatggcgca
    17581 gctgccagcg ttatccagca gccgcgtttg gttaacaagc gaggcattta cggtcggaca
    17641 atcagcagat cttcagccgc gccggtcgcc cgccattggg gaacatacat tgattccacc
    17701 atcggttgcg gtacctgata cgttcccggc gtcaccgccc gcgccagata caccagcgtt
    17761 accggttggt attcatcaac ggcaaccgcc gccacaaagc gatcgtcacg gaactcaatg
    17821 tgcttaatgc tcgcctgctg catctggttc agtaagtttt gcacttcgcc accactttgc
    17881 tccaggctgg cgctaccgtt cgccagattc tgattttcca gttccagacc cgcaggcagc
    17941 agatccacga ctaacgcatc cggcacgctg ttactggctt ttacctgcaa ccagaccagc
    18001 accagatcgc cgctacgtaa cgagtccagc gatttgctct taccatcagt accaagaata
    18061 tgacgctcga tttgcagcac attgttcgcc ggtaaaggtg cggattgcgg ataaccgctg
    18121 gcatccatac gcaaccataa cggctgatcg ccactgtttc tcacctgcaa ggtggcaagt
    18181 tgatcgctat tcagattgct gtttagcgtt ttctcgcctg tcagcggctc agctgagaaa
    18241 gaggtttgcg cctgccattt acccggtaaa tcctgaatcg tacgggcagc caggaacaac
    18301 gcgttacttt cctgcgtcga tagccagcgt tcaccaaatg cctgctgcga aagcgtgttc
    18361 agcaaagtgt tctgctcatc gggtagcagt ttattttctt ccagcaagga gagcattaac
    18421 gcgttgtcgc gcagtggact accgtaatca cccagccata tccgctcatc actatttctc
    18481 ggcgttttca gcgccagcac aatcgcttct tcaccacgcg ttgcatcacc catggttttc
    18541 agcgcaacgc caagttgcag cagcggtaaa ccagaagcgg catctgcacg atgctcccag
    18601 atttcacgca gcgcacccag tggtgctttt tgctgacggg ccagcaccag cgcagcgtaa
    18661 gactgaacgg cgaatttact ggctttgaga ttatccgcgt acgggatcga catcatgccc
    18721 ggatcttgta aatagcgcag cagacgctca ttaccccggt taatggcgtc tgtcggcacg
    18781 ctgtaaccct gttcgcctgc gcggaccagg aaatccatca cgtaagccgt cagccagtac
    18841 tcttcgtcac cgtttttatc ccacagcgca aagccgccgt tatcacgttg catttgcagc
    18901 aaacgggaaa tgccgatatc gaccgatgca cggcgtttct catcactgtc gcctttgatg
    18961 cccaacgcct gcagttgggc tgcgttggta taaagtgacg ggaacaggcc gctggcggtt
    19021 tgctcaagac agccgtacgg atacgctttt aactctttga tataacgtgc aatgttcagc
    19081 ggtggtttgc cgctcaacaa caattgccct tccagcgtaa caggcgagaa gttttgcaat
    19141 ccatccgccg gaatcgccca tgtctcacca ggctgtaacg ccgtaccgta attaaccgtt
    19201 tgtgccggga acgccggacg gacgccgatt ttccactgct tatgctgatc ggcaacggtt
    19261 tcacccggta acgctaaccc gctaatggtg gcctgaattt ctccatcgcc ataacccggc
    19321 aatgctcgca ccgggataaa cagcgtagta cgcacacctg gcgctaattc aacggctgcg
    19381 ggtgaatcgc tgaccagttc aagcaaacca ctggcggtca gggcaacgtt cagtttttgc
    19441 ggtttatcgg taagattagt gatatccagc gtcagacgcg aggtatcgcc actcgccata
    19501 aagcgcggca tgttcagttc agcaatcacc ggtgcggcaa ctatcacttt gctttcgttg
    19561 ctaccgaaat catctgccgt ccaggcttgc gccatgacgc gcaattcacc gttaaaatcg
    19621 ccaatcggca gtgtaaccga gccttcgccc tgttcgttga gcgttaccgg cagcgcctgc
    19681 tgcgcgacaa tattgacgtg attgaccggc ggtttaccac cacgtttcag ctcatcacca
    19741 tcgccaccga aacgcagagc tgccagacgc ccctgacctt caataacctg accgtaaata
    19801 tcgtaaatgt ctgcgccata gcgtttctga ccaaagaacg cctgccacgg atctggcgtg
    19861 acgtagtcag taatattcag cacaccacta tcaacggcag acaccagcac attcacctgt
    19921 ttaggcttct cgccattttt agtgctggct ttaattttca cggttaatgg ttgattcggc
    19981 cgcatttttg ctggtgtttc cagcgccaga tcgaggcgac ggttttcatc gccaagcggc
    20041 agatgcaaca ccccaactgc gcgttttggc gtcgcggagc gagatttatc gccaggacgt
    20101 actaccagcg tacttaaata cagatcatga cgattccagg ttttatcgac cggaatcgtc
    20161 agatccagcc cttgagccgg aacatcaatc tcttgccacc acaacggccc ttcactggac
    20221 tcgaccatcg cataaccttt acccgccgtt ggcgcggcaa tatgcaactt aatggtatcg
    20281 ccagggcgat aactggcttt atccagtttc agcgtgacac ggtcgggtcg cacggcaccg
    20341 ctcccgtcgc tgttgtcctg ccagctatag ccagcccaga aacgcacgct actgaccgct
    20401 tcattcggcg ctttgacttc cagacgataa gcgccccact ctaccgggaa actgacctta
    20461 ccggtttcat ccgcctgaag atccagagtt tgttcatttt cgatcagatc tttttgatca
    20521 aactgtgact gccagccttc atcttctgac cagttccagt agtaatcgcg gcgttcgcga
    20581 atcaggcgca cctgcaagcc cgacacggct tttttcacgc cttgcgcatc gctataaacg
    20641 atgtcaaaac cggcgttact gccttcatca acaatgggct gtttcaccgt gctgtcagtg
    20701 cgataatcgt aaaccgattt cgaggcgaac tgcggacgga tccccggcaa tgcatcggca
    20761 ggccagatag cctgctcagc gcggcgcgtc accgggcgac cgcccgattc cagcaaacta
    20821 ccctggaaaa taacctgtaa tggggaatgc gtttccttcc actggctttc tgtagaaact
    20881 tcgccgcgcc ctttatcatc cagcgtcaac tgaacttcat ccagcgtgcg ggaaagattt
    20941 tcggcagcta tatcgccgaa ttcaaaacca ggtaaggctg acacagcttc acgcagtggg
    21001 cgcaggaaaa gttgcccttg caaagtatta ccattagcag gtgcaccata caggtagtac
    21061 cccaccacgg agaatttcac ttcatctttc ggcgttagcg gggttttctc accggtcaga
    21121 ttcagcgcca tgcgctctgg cataaaatct tcgacgtgga aatcccacat ccgatactgg
    21181 ttatcgcccg tgttagcgcg aatatgccac ataccggttg ccgcattgct atcgagtggc
    21241 caggtaaagt ggtagaggcc attctccggc tgactaacga cgctcctgag tacctgccca
    21301 tcgggtttaa tcacgtctaa cttgatgggt tgattgggca acgctttacc gtctgcatca
    21361 cgcagcaaac cattgaggat taccgtttca cctgggcgat aaagatcgcg tgggccaaac
    21421 atgaaaaact gtttgctata gcctggcgcg ccagcaatgt taaattctgc taagtccagc
    21481 gccggaagtt ttaaatcgag tagcgttgtc tgaccgtctt tacgcgccaa cagtaatgcc
    21541 gcgtttttat cattttccag ctgcacatgc ccctgagcgt cactggttgc ctgagtcaga
    21601 gtctgccctt tctcatttaa taaagagact tcaattcctt gctgggccgc gccgttttcc
    21661 agactttggg taaagatatc cagacgattg tgataacggt gagctgaaac gccgatatca
    21721 cttaacgtaa acagcgtcgc gggattactg taatcgtaac gtccagcctg attcatcaca
    21781 gccagataca cgcccgcctg ctgaagcggt ttgatatcgc ccagcggcag caataatttt
    21841 tcacgggtgt tacgcgcagg attgagatca aaccgtccgg tgtagaccag atccgccatc
    21901 tgcagcagtt tgtctgactg ccagttcgcc agcgaattgc ggtattccca ttggctaatg
    21961 aatgctggca gagattctgg cttaacgcgg aagaagttaa catcgacatt attaacgttg
    22021 agcgccatta ccggcagccc ttcaacgact ttaccaggca gcagcgaacc acggctggca
    22081 aaaccgacgc tgggttggat gtcgcgggta gttatagttt tttcgtaatc tttactgaag
    22141 gttgcgttgt tgagtgcttt gacctccttg ccaatagtaa cgatcaaatc acgtttcggt
    22201 tcgaggtggc gtaaacgtaa ctctttaaga ttatctgaca gctcccaggc accatccact
    22261 ttgccgcttt ttttatcgac gacatgaata acgcgtgaga aatcctgatc cgggtcgaga
    22321 gggatggaga acgtcagcac cagcgtggct gcaccatcaa gttggacttc agagagatcc
    22381 agtaatgtca gcaccttacc ggcactctgt tgggccagtt tttgtctctc cggcacggag
    22441 agttttgctg aactcgcgtt ttctgaagag gccgctttag taacttcaga aggcgcatct
    22501 tttttcaccg ctgttggcgc gttatcgttg ttgtcgcacc ctgccagcgc cagcattagc
    22561 atgcaggcgg ctacgcgtaa ctttttcatt tttcatccct gccacaatgg cccgttagca
    22621 acgtcgaata attattatgc gtgagaattt acgttatgta attcagtatc acgcccatac
    22681 aatccgaatt ttagtgagaa ttgtggctca gacagccaaa tcagcctctt tcgcttgtcg
    22741 cttttcacta aacatccgac aatttagcct aaccccggca aaaatggaga tgcctatgtc
    22801 cacgacatgg tttgtaggag ccgactggct cgccgaacat attgatgacc cggaaattca
    22861 gattatcgat gcccgcatgg cgtcgcctgg acaggaagat cgtaacgttg ctcaggagta
    22921 tctgaatgga catattcccg gcgcagtgtt ttttgatatc gaagcgcttt ctgatcacac
    22981 ttccccgctt ccgcacatgc tgccgcgccc ggaaacgttc gccgtggcga tgcgtgaatt
    23041 aggcgttaac caggataagc acctgattgt ctatgacgaa ggtaatcttt tctcagcccc
    23101 acgagcatgg tggatgctgc gcacctttgg tgtagagaaa gtgtcgattc tggggggtgg
    23161 acttgcaggc tggcagcgcg atgatctgct gttagaagaa ggtgcagtag agctgccgga
    23221 aggagagttt aacgccgcgt ttaatcctga agccgtggtg aaagtaaccg atgtattatt
    23281 ggcaagccat gaaaatacgg cgcaaattat tgatgcccgc ccggctgcac gttttaacgc
    23341 agaagttgat gaacctcgcc caggtttacg tcgcggacat attcccggag cactgaatgt
    23401 tccgtggacg gaactggtgc gcgaaggcga actaaaaacg accgatgaac tggatgcgat
    23461 attttttggt cgcggcgtca gctacgacaa accaattatc gtcagctgcg gctctggtgt
    23521 aacggcagcc gtggttttgt tagcactcgc gacgctggat gtgccaaacg tgaaactgta
    23581 cgacggcgca tggagtgaat ggggcgcgcg ggcagattta ccggttgagc cagtgaaata
    23641 agtattttac aggcaataaa aaaccgccga atttggcggt tttttattgc tggtctggtt
    23701 cgcggccttt ccagcaggtt gtattaccgt agtaatgcaa gcgcgtctca gcggagacaa
    23761 tactcgccag taactctctt tttgtcaagc aaaagagagt tattattgtt ctgttagtgt
    23821 attatccact gcggcccttt ccgccgtctc gcaagcgggc gctggcttaa ggaaaggatg
    23881 ttccgcgacc gttagagcaa gcgcgtctca gcgcttgcta tcgcggcaat atcgccagtg
    23941 gtgctgtcgt gatgcggtct tcgcatggac cgcacaatga agatacggtg cttctgtatc
    24001 gtacttattg tttctggtgc gctgttttcc caagtaaata ataaccggag tctctccggc
    24061 gacaatttac tggtggttaa caaccttcag agcagcaagt aagcccgaat gccgcccttt
    24121 ggggcggcat attttagatt atccgattct gtttaaagtc acgcaaaaaa ccaccccagc
    24181 gacgttcata gaatggcaca atatgttcgg taataaagtg gctaattcct ttttcccctt
    24241 ttttcacctg acaaatatcg attggttcat cgccaggtaa tgtatcggtc gctacacttc
    24301 ccgtcgcctg aataatttct tcgatatcac catcggcttc aatgccaata agtaaattag
    24361 gctgtgcctc ttcgttctct ttaattgaac aaataaaagc acgcttcacc gacttaatgg
    24421 ttttaaataa ggtggtgagt gaatcaatca tttgtgctgg cggctctgcg acttccgata
    24481 atatcagcga ttcaccgcct tccaggattt cctggctgct cagcggattt ccctcttcac
    24541 caatcaacaa actgatttca cgcggcataa attctttacc ggtcggcagt ttggcattaa
    24601 ggaagagcgt ttcgccaagg gtcatctcaa acaatgtgcg aacgggcatt acgacaaatg
    24661 cctgttcgtc ttcaaccgcc tgttgaagcg cttctaacga ggtgaaaaaa ggaatgacgc
    24721 tggtgccgtc ttctttttcc cagtgctgta aatcaagcgc actatcttca accacagcct
    24781 cgccctgcgc cgccgtacca ggcacccaga cggtggattc cagtagagta cggaaaaagg
    24841 ccgggcggtg cgccggttcg gttgctgctt tttccagcag gtcttcaagt tcgttttttg
    24901 tttcggacat atgaaccaca attcattcaa cgttcggggc gcaaatgcct gatgcgctac
    24961 gcttatcagg cctacaaggg attcgcaatt tgttgaattt gcagaatttg taggccggat
    25021 aaggcgttta cgccgcatcc ggcatattag tttacgccgt taacagatta gctatcgtgc
    25081 gcacaccaag tcccgtagcg cccgcagacc actgttcaac cggcgcttta cggtaagtcg
    25141 ccgagcagtc gatatgcagc cagccttgct gatagttctc aacaaagtgc gacaggaagc
    25201 ccgccgccgt gctcgcgcct gccggatacg ccgcgcttcc ggtattgttc agttcggcaa
    25261 agttagacgg cagctggctg cggtggaatt ccgccagcgg cagacgccag aatggttcgt
    25321 tctcttgtga ggcactcgcc agcaaacgac cggcaagcgc atcgtcaaaa ctgaacagcg
    25381 cgtgataatc attacccagc gcagttttcg ccgccccggt gagggtcgcc gcatcaatga
    25441 tcatttccgg tttctgcgca ctggcatcaa tcagaccatc ggcaagcacc agacgccctt
    25501 cggcatcagt gttcatcact tcaacttttt taccgttgcg ataggtgatg atatcgccca
    25561 gcttgaacgc attgccgcta atcaggttat ccgcacagca gaggaacagc ttcacgcgct
    25621 tgttcagtcc gcgcgtaatg gcaaatgcca gcgccccggt aaccgttgcc gcgccgccca
    25681 tgtccgactt catcgagtcc ataaacgcag tctgtttgat gctgtagccg ccggagtcaa
    25741 aagtgatacc tttacctacc aggcacgcgt acaccggtgc ttctttatcg ccagttgggt
    25801 tgtaatccag cgccagcaat accggagaac gttctgaacc gcgcccgacg gtgtgcagcc
    25861 ccatataacc ttgctcacgc agatcttcgc ctttggtgat ccgataagtc acacgatcgc
    25921 ccgcgacgtt gctgatcaga tcaacagcac gctgtgccag ttgcgatggt cccaattctt
    25981 ctgccggtgc gttgatggtg tcacgcaccc agtcgatgat catcaggcgg ttatccagtt
    26041 cctggcgctg ggcatcgtcc agatccggcc actccacttt acgcgtgcct ttcggggctt
    26101 tgtaaccttg ccagaatgcc cagcagcgat ccgcatccca gccttcaccg cttaactgaa
    26161 catgcttgat gcccagaccg tcaatcttgc gcgccgcacg ctggatcagc cccagatcgt
    26221 ctgccccgtt caaatgcagg gtaatgccgt cattattaat gctgtaagtt gctttttctc
    26281 cccagcgcgc gtcggcaggt tgggtagaga gggtaatctt catcgcttct gtcattttag
    26341 ttatccttct ttgtaaaagg gccgccagtt ggcagcccca ggatttttcc gctaaatgat
    26401 tcgcgttgca ggaaggcggc aagtgagtga agccccagga gcatagataa ctatgtgact
    26461 ggggtgaacg agcgcagcca acgcatctgc ggcgtgaagc atgacgcgga aattattcgg
    26521 cctcgtccag ccagactaac aaaatcgctt cgaggatttt ctcgttggat gcctgcgggt
    26581 cgtcgtcgaa atcttccaga tcgcaaatcc actgatgcat atcggtgaat cgaaccgttt
    26641 tcggatcaag atcgggatac gcatcgtaca gtgcttcgcc aatttcgcgg ctatcggtcc
    26701 atttaagtcc catactaacc tctgttaatg ctcacgcgca tggttgatag tgtaacgcgg
    26761 gatttcgacc actaaatctt cgtcggtgac gcgcgcctgg cagcttaaac ggctttccgg
    26821 ctccagtccc caggctttgt ccagcatgtc gtcttcctgc tctgagcttt ccggcagcga
    26881 gtcaaaacct tcacgaacga tgcagtggca ggtggtgcaa gcacaggatt tttcacaggc
    26941 gtgttcaatc tcgataccgt tacgcagagc tgcgtcgaga atggtttcac cgctattagc
    27001 ttccagaaca gcgccatcag ggcagagatc ctgatgaggc aaaataacaa tctttggcat
    27061 attaaacctc gtccacggaa tggcctttca gcgcacgacg aaccgactgg tccatgcggc
    27121 gagcggcgaa atcctgggtt tgtttgtcta cgtttttaat cgcttgttcg atggcgtcaa
    27181 cgtcatcgcc ctgcgccact tcactcaggt gagcggcagc atcgtcaatg acctgacgtt
    27241 ctgcggcgct taacagcgcg gcatcagcag ccagcgcgcc gtgcagactt tccagcacac
    27301 gcgccgcttc tactttttgt tctgccagca ttcgggcttt tacgtcctgc tcggcatagc
    27361 tcattgagtc tttgatcatc gaagcgattt cgctatcggt cagaccgtaa gacggtttga
    27421 cctgaataga cgcctcaacg ccggtggatt tctccatcgc cgtcacgctc aaaagaccgt
    27481 cggcatcgac ctggaacgtc acgcgaatat gcgcaccacc agccggtagc gccggaatac
    27541 cacgcagcgc aaaacgcgcc agtgagcggc agtcctgcac cagttcgcgc tcaccctgca
    27601 ttacatggat agacatcgcc gtctgaccat ctttaaaggt ggtgaaatcc tgagcgcggg
    27661 ccaccggaat agtggtatta cgcggaatca ctttctccac caggccgccc atcgtttcga
    27721 ggcccagcga cagtgggatc acatcaagca gcagcatttc gctgtctggc ttgttaccca
    27781 ccagaatatc cgcctgaatc gccgcgccaa tagcgacgac tttatccggg tcgatggaag
    27841 tcagcggtgg acgaccgaaa aattcgccta cccgttcacg caccagcggc acgcgagtag
    27901 aaccgcccac catcaccact tccagcactt catcagcttc tacacccgcg tctttcagcg
    27961 cgcgacgaca agccagtaag gttcgtttta ccagtggcgc gatcagttca ttgaattgtt
    28021 cacggctgat ttcgccctgc cagcccgcaa cgttaacggt cacggagtcc gcatcgctca
    28081 gcgcgatttt ggctgcaatg gcggcatcca gcagttcacg ctgaacgcgg ttatcgctac
    28141 gatcaggaat gcccgcctgc tcgcgaatgt aatccgccag cagatggtcg aaatcatcgc
    28201 cgccgagcgc ggaatcaccg ccggttgcca gcacttcaaa cacgccgcga cttaagcgca
    28261 gaatggaaat atcaaacgtc ccgccaccga ggtcataaac agcgatcacg ccttcctgac
    28321 cggaatccag cccgtaggcg atagccgcag cggtcggttc gttaagtaag cgcagaacat
    28381 gcaaccccgc cagacgcgcc gcgtctttgg tgccctgacg ctgggcatcg tcaaagtacg
    28441 ccggaacggt gataactaca ccatccagct cgcctgccag ggcttcagtt gcccgcgccg
    28501 ccagtgcttt gaggatgtcc gcagaaacgc gcaccgggtt cagcagcccc gccgccgttt
    28561 caatcatcgg caggccgttt tcgctggcct ggaattgata aggcagatgc ggatagcgtt
    28621 gctggatatc agccagcgag cgtcccatca ggcgtttaac agaactaatg gtgttggcgg
    28681 tgtcaagcgc tgcgttagta cgcgcgtcat aacccaccga atgcccttgc tgttgatagt
    28741 gaacaacaga tggcagcagg tgacggcctt catggtcggc taacgtttcg gcctgaccgc
    28801 tgcgcactgt cgccaccagc gagttggttg tgcccaggtc aataccagcc gccagacgac
    28861 gctgatgcgg cgcagcactc aaaccaggtt cactaatttg taataaggcc atgtttagct
    28921 tccagaaatt aaaaatcgag cagtttttct tcgagttgtt cggcactgct ccgcagttta
    28981 tcgagaaaac gcagcttacg cacggtatcc gccgccgcgt cccacgcctc gttgtctaac
    29041 tgttcaacca tcaactgatg gcgggtatca aacatctttt tcacacgttt gataaagctt
    29101 tccagccgcg cttcatcttt cgcctgttcg atctcgtcca gctcttcgcg cagctccaac
    29161 tgttccatca ggaacgcggt gtcgcgcaca gtatgctgct cgctggcgag atcaaaaccg
    29221 tgtaaagaaa gcaaatattc cgcgcgcatt aacggatgac gcagcgtttg ccaggcctgg
    29281 ttaatggttg cagattgctg tacggcggcg agttgttccg cctggcttcc gctggcgaat
    29341 ttatcaggat gatactgacg ttgtagatcc tgaaaacgca ggctcagcgc ctgggtatcg
    29401 agttgataac gggcaggcaa gccaaagagg gtgaagtaat ccataacatt ctcagggctg
    29461 cgatccgccg cgataacggc gaatcaggta aaacaaaccc cacgcgcagg cgaccacggt
    29521 ggggttatcg gtatgcgcat caaacgtgga agctttcgcc gcaaccacac tcatctttaa
    29581 cgttcgggtt ggtgaattta aacccttcat tcaggccttc ttttacgaag tccagctgcg
    29641 taccgtccag aaattgcagg cttttgccat cgaccacgac tttcacgcct ttgtcttcaa
    29701 acacgatgtc ttccggcgtc ggttcgtcaa caaattccag tacataagcc atacctgaac
    29761 atccggaggt tctcacgccc agacgcaggc caaacccttt gccgcggtta gccagaaagg
    29821 tatttactcg cgctgctgca ctgtcgctca gtgtaatcga cataaccaaa cctcaactct
    29881 tattttgctt cacgtttgct tttatagtcc gcaatggcgg ctttgatcgc gtcttctgcc
    29941 agaatagaac agtgaatttt caccggcggc agttcaagtt cttcagcaat atcggtgttt
    30001 ttgatcgcct gcgcttcgtc gagagacttc cctttcaccc attcggtgac cagggagctg
    30061 gaagcgatag cagaaccgca gccgtaagtt ttaaaacgcg cgtcttcaat gataccttca
    30121 tcgttgactt taatctgcaa cttcatcacg tcgccacagg ccggtgcccc caccatgccg
    30181 ctgccgacgt tctcgtcgtt gttgtcaaag gaacccacgt tacgcggatt ctcgtaatgg
    30241 tcgataactt tttcgctgta agccattata aattctcctg attccgatac cgattaatga
    30301 tgagcccatt cgatgctgtt cagatccacg ccctgcttgt acatttccca cagcggagaa
    30361 aggtcacgca gacgaccgat ggatttacga actaactcga tggtgtagtc gatctcttct
    30421 tcagtagtaa aacgacctaa agagaaacgg atagagctat gtgccagctc gtcgttcagc
    30481 cccagcgcgc gcagcacgta ggacggttcg aggcttgctg acgtacaggc ggaacctgaa
    30541 gaaactgcga ggtctttcag cgccataatc agcgactcac cttcaacgta gttgaagctg
    30601 acgttgagaa tgttcggcgc accgtgttcc aggtcaccgt tcaggtaaac ttcttcgata
    30661 tctttgatgc cgttccacag acggttacgc aggccgcgca gacgttccat ctcggtcgcc
    30721 atctcttctt ttgcgatgcg ataggcctcg cccattccga cgatctggtg aacaggcaga
    30781 gtgccggaac gcataccgcg ctcgtgaccg ccgccgtgca tttgcgcttc gatgcgtacg
    30841 cgcggtttac gacgtacata cagcgcaccg atacctttcg ggccatagat tttgtgaccg
    30901 gagaaagaca tcaggtcaac tttcaactgg ctcaggtcga taggcagttt gcccacgctc
    30961 tgggttgcat caacgtgata gataatgcca cgagcacggc acatttcgcc gatagccgcg
    31021 atatcctgca ccacgccgat ttcgttattt acgtgcatga tggaaacaag gatggtgtcg
    31081 tcacgcatcg ctgcttcaag ttctttcagg tcgataatgc cgttacgctg cggtgccagg
    31141 taggtgactt caaaaccttc gcgctccagc tgacggcagg tatccagtac cgctttgtgt
    31201 tcggttttgc tggtgatgat gtgcttgcct tttttctgat aaaagttggc tgcacctttg
    31261 atcgccaggt tgtcagattc ggttgcacca gaggtaaaga cgatttcacg cggatcagcg
    31321 ccgaccagat cggcaatctg attacgggcg atatctaccg cttcttcagc ctgccagccg
    31381 aaacggtgag aacgagaggc cgggttacca aaggttccgt ccatcgtcat aaactgcatc
    31441 attttctcgg caacacgcgg gtccaccggc gtggttgcgg agtagtcgag ataaatcggt
    31501 aatttcattg ctctataaac tccgtacatc actcaatgca aggaaccagg ctaccggctg
    31561 gatgtacgac cgtgtttacg gagcgcgata cgccccggcc tgattctgaa ttctttttat
    31621 taagcgcgta acttaacgtc gatcgcgtct tgtatgcggg tgcgtggcgc gtcgtgagta
    31681 tgctgacgac cagacacatc cagcacttcc tggttattaa ccagttcgcc taaagtaatg
    31741 ttgttgagaa aaccggtgag acggtcgctc aaatcacgcc acagcgcgtg ggtcaggcat
    31801 ttatcgccgc cctggcagcc gcctttaccc tgacaacggg tggcatctac agattcgtca
    31861 acggcgctaa tcacttcgcc aacggcgatg ctgctggcat ctttgcctaa cagataacca
    31921 ccgcctggtc cacgtacgct ggaaaccaga ccatttttac gcagacggga aaacagttgt
    31981 tccagataag aaagggaaat tccctgacgt tcggaaatat cagccaacgg taccgggccc
    32041 gcttcagagt tgagcgcaac gtcaagcatt gcggtcacgg catagcgccc tttagatgtc
    32101 agtctcatgt cttacttcac ctcaaactcg cccctgcccg gggtttttta ttgtaaaagt
    32161 gggggtattg catagcaggg tcaagtctga cattcccgag taaattggtc aactatttac
    32221 ttgactgatt tagtcgggta tttaaccttc agtgccattt ttttatcgtg gcgtttgtac
    32281 ctgttgtcct tccagaccat gggcgggttg agggcaatta ttcgcattag cgctggcctc
    32341 ttcccctcac cctaaccctc tccccgaagg ggcgagggga ccgtccgtgc atttatctgg
    32401 cttagccctc aggccttatt acctttattc tgctgctcaa tagaagccag aatcccgcgc
    32461 aggatattca attcctggct ttccgggcgc gcacgggtaa acagacggcg caatttattc
    32521 atcacctgcc ccggatggtt ttcacggata aaaccggttg ccagcagcgt ttgttccaga
    32581 tgaccataaa aacgctccag atcatcgacc agcggatacg gcgtctcttc atgctcgacc
    32641 tgctcgccgt tttcctgagt tgccagccag gccatgcgca cttcataggc aataacctga
    32701 accgccatcg ccaggttcag cgagctgtat tccgggttag ccgcaatcgc gacatgataa
    32761 tggcatttct gcaactcttc attggtcaag ccgacgcgct cacgaccaaa caccagcgcc
    32821 accggggtat ttgccgcttc agcgacgctt ttcagaccgc attcgcgcgg gtcgagcatc
    32881 ggccacggca gcgtgcggga gcgtgcgctg gtgcccacca ccaggctaca accggctaac
    32941 gcttcgtcga gcgtatcgac gatgtgagca ttaccaatca catcgctggc ccctgctgcc
    33001 agggcaatcg cctgggagtc gggtttcacc agtggattaa ccagccacag attggttaat
    33061 cccattgttt tcatggcacg ggcaacagaa cccatattgc cggtgtgtga cgtctccacc
    33121 agcacaattc gaatattttg cagcattgtc tttcttcatc taaagattat tcacgcatct
    33181 tatcataaaa cgaagacaga tgccgatctc gctgctatac tctgcgccgt tttcccgttc
    33241 tttaacatcc agtgagagag accgatgcat ccgatgctga acatcgccgt gcgcgcagcg
    33301 cgcaaggcgg gtaatttaat tgccaaaaac tatgaaaccc cggacgctgt agaagcgagc
    33361 cagaaaggca gtaacgattt cgtgaccaac gtagataaag ctgccgaagc ggtgattatc
    33421 gacacgattc gtaaatctta cccacagcac accatcatca ccgaagaaag cggtgaactt
    33481 gaaggtactg atcaggatgt tcaatgggtt atcgatccac tggatggtac taccaacttt
    33541 atcaaacgtc tgccgcactt cgcggtatct atcgccgttc gtatcaaagg ccgcaccgaa
    33601 gttgctgtgg tatacgatcc tatgcgtaac gaactgttca ccgccactcg cggtcagggc
    33661 gcacagctga acggctaccg tctgcgcggt agcaccgctc gcgatctcga cggtaccatt
    33721 ctggcgaccg gcttcccgtt caaagcaaaa cagtacgcca ctacctacat caacatcgtc
    33781 ggcaaactgt tcaacgaatg tgcagacttc cgtcgtaccg gttctgcggc gctggatctg
    33841 gcttacgtcg ctgcgggtcg tgttgacggt ttctttgaaa tcggtctgcg tccgtgggat
    33901 ttcgcggcag gcgagctgct ggttcgtgaa gcgggcggca tcgtcagcga cttcaccggt
    33961 ggtcataact atatgctgac cggtaacatc gttgctggta acccacgtgt tgtgaaagcc
    34021 atgctggcga acatgcgtga cgagttaagc gacgctctga agcgttaatg actcaggcgg
    34081 gtgatgtcac tcacccgccc tcgcctttca ggcgctattc tgaaatactt cctcaccgct
    34141 ttactttctt tcgtcactct cccaccatct ttccccgatt aatggatgat aaagaagtcg
    34201 caaggaaagg ttatggcact gccagtgaac aaacgcgttc ccaaaattct gtttattctc
    34261 tttgttgttg ccttctgcgt ttatttagtg ccgcgcgttg ccatcaactt cttctattat
    34321 cctgacgata aaatttacgg tcccgacccc tggtcggcgg aatccgtcga atttacggct
    34381 aaggacggta ctcgtctgca aggctggttt attccttctt cgacgggccc tgctgacaac
    34441 gccatcgcaa ccatcattca tgctcacggc aatgccggaa atatgtccgc ccactggccg
    34501 ctggtcagtt ggttacccga gcgtaatttc aacgttttta tgtttgatta tcgcgggttt
    34561 ggtaaatcaa aaggcacgcc gtcccaggcc ggattgctgg acgatacgca aagcgccatc
    34621 aatgtggtgc gccatcgcag tgatgtaaac ccacaacggc tggtgctgtt cgggcagagt
    34681 attggcgggg cgaatattct tgctgttatt ggtcagggtg atcgtgaagg catacgtgcg
    34741 gtgatcctcg actccacatt tgcctcttat gcaaccatcg ccaaccagat gatccccggc
    34801 agtggctact tacttgatga gagttacagc ggcgaaaatt atatcgccag cgtcagcccg
    34861 atcccgcttt tactcattca cggtaaagct gatcacgtta tcccatggca gcacagcgaa
    34921 aagttgtata gcctggcaaa agagccaaaa cggttgatcc taatcccgga tggcgaacac
    34981 attgatgctt tttccgatcg ccacggcgat gtttatcgcg aacagatggt ggactttatc
    35041 cttagcgcgt tgaatccgca gaactaaccc atgatcgcta gcacgataat cattcacaaa
    35101 accaccttaa gacatgctaa tccactggtc agaacagttt aagatgagaa aaattctgtg
    35161 acgcttgcca acatttctga tgattagcat tcccttcgtc atttccctga gcaaacttta
    35221 gctattctta tcaattatgc ttatgggaga tctacagatg atgcctacgc ttgctccacc
    35281 atctgtcctt tcggctcccc agcgccgctg ccagatcttg ctgacgctct ttcagccggg
    35341 gttgaccgcc accacggcaa ctttcagcga gcttaatggt gtggatgatg atattgccag
    35401 tcttgatatc agcgaaacag gacaggagat cctgcgctat catcaactca cactgacggc
    35461 tggttatgac ggtagctacc gggttgaagg tacagtgctt aaccaacgtt tgtgtttatt
    35521 tcactggcta cgacgtggtt tccgtctgtg tccatcattt attaccagcc atttcacccc
    35581 cgccctgaag agtgaactga agcggcgcgg aattgcgcgt aacttttacg acgataccaa
    35641 tctacaagcg ttagtgaatc tctgctcccg acggctgcaa aaacgctttg aaacgcgcga
    35701 tattcatttc ctgtgtctgt atctgcaata ttgtttgctg caacaccacg ctggaattac
    35761 gcctcagttt aatccgctcc aacgtcgctg ggcggaatcc tgccttgaat ttcaggtagc
    35821 gcaggaaatt ggacgccact ggcagcgtcg ggcgctccag cctgtaccac ctgatgagcc
    35881 actgtttatg gcactacttt tttccatgtt gcgggttccc gatccactgc gggatgcgca
    35941 tcagcgagac agacaattgc gtcagtctat caaacgtctg gtaaaccatt ttcgtgagct
    36001 gggaaatgtt cgtttttatg atgaacaggg gttatgtgat cagctttata cccacctcgc
    36061 ccaggcgtta aatcgcagtt tgtttgccat cggtattgat aataccctgc cggaagagtt
    36121 cgccagactg tacccacgcc tggtgcgcac cacccgcgcg gcgctggccg gatttgaaag
    36181 tgaatacggc gtccatcttt ctgatgagga aagtggtctg gtcgcggtga ttttcggtgc
    36241 ctggctaatg caggaaaacg atctgcatga aaaacagatt attcttctta ccgggaatga
    36301 tagcgagcga gaagcgcaga ttgagcagca gttacgcgaa ctaacgttac tgccgctcaa
    36361 cattaagcat atgtcggtaa aggcattttt gcagacaggc gctccgcgtg gcgcggcact
    36421 gattattgcg ccttatacca tgccattacc gctcttttca ccaccgctga tctatacgga
    36481 cctgacgctg acaacacatc aacaggagca gatccgcaaa atgctcgaat cagcatgagg
    36541 gaacaacttt cgggcgcaaa aacattgccg gaagcgccac cagcgccatt acccagaaca
    36601 cgccgtggcc cagatattga tacaggaaac cggcgaaaac ggtcatgata gcgatactgc
    36661 cgcccatcgc gacggcagag taaaccgcct gtaaacggat gacttcgcta ccctggcgag
    36721 cagcaatata acgcatggcg gccaggtggc agaccgtgaa ggtgccgcaa tgcagaattt
    36781 gcaccactat caaccacggc aacgccgtag ttgctcccat aatgccccag cgcactacgc
    36841 cgcaaatcgc cgagatcaac agcatatcgc gtgcactaca acggcggaaa agtttattac
    36901 tcagcgcaaa gataatgact tccgccacca cgcccagcga ccacaaatac cccaccgccg
    36961 aggccgagta gccagctgcc tgccagtaaa tggcgctaaa accgtaatag gccgcatgtg
    37021 ccccctgcaa taaacaaacg caggccagaa agcgccagtt ctggcgaacc agcgccaacc
    37081 acgctgacca accggtgctc tcctgctggc ggcttgcccc ttgtggctga atcgtcggac
    37141 ggatgagaaa gccgagcagc atggatgcca cgcccaacgt caacagcgcg aggatcaccc
    37201 gataatcaaa catagtgacc agtttgcccg tcagcgccga gccaatgaca aacgccaccg
    37261 agccccacag tcgcactttg ccgtaatcaa gcgggaactg cttttgccac gtattcgcca
    37321 gtgcatcggt caacggtacc agcggtgaga aaaagaggtt aaagccaatc atcaccagca
    37381 tcagccacgc tacgtgcgcc cccgcccaga aggcgacagc aaagagaagt gtcagcagtg
    37441 ccagcacgcg caaggcggaa atcaggcggg aaggatcgct gacgcggggc gcgatgagca
    37501 aactcccgag aaaacgggca accagacctg cccccaataa caggccgatg gtttctggcg
    37561 ttaaaccaat ccctttaagc cagacgctcc agaaaggtag aaaaatgccg taactaaaaa
    37621 agtatgtgaa atagccgagc gccaaccagc gcgtggattg caaaaccatg agtccctccc
    37681 gtcaggaggc gttagtctgg ggttaatcga atgttggtgc aagttgaaaa ataagaatat
    37741 tcgagcctgc ttcccgatgt ctgtaacgcc agttcacaag cactaaaaaa ctgcgatccg
    37801 cgacgcatgt tgcaaaaata atgcgtaatt atgccgttac gtttgccaaa cgttcctgca
    37861 caatggcgat gaaatcgcgt aatgccggct tcatctcccc tttcttccac gccatcagta
    37921 aagcaatgga aggcacattt ccggcaatgg gacgaaaaac aacctgtccg gtattaaaat
    37981 tattcatata accgggtatc aaagtgacgc ccagccccat gcccaccaga ttcatggtca
    38041 ccagaatatt cgttgccacc tggacgatat ttggctggct gttttcttgc gcaaaccacg
    38101 ctttaacgat cggagcaagc gaaccggaat acgccggatc ggtactgacg aaattcacgc
    38161 catccagttg cgcggcggtg atctcttttt catgtgctaa agggtgatca accggtaaca
    38221 caaccactaa tggttcgtca aaaagctcca gataatcaat ctccgggcta taaacaggat
    38281 ggcgcattaa gccgacgtcg agttcaccac ggcgaatttt ttcctcctgt tgcgtggtga
    38341 ttaaactcac cagctcaatc aaggtgtctg gctgtctgag acgaaacatc ggtaatactt
    38401 ttggcagtaa attcacttcc gccgatggca caaagccaat ggttaattgt ctgtcttcct
    38461 gaacaatttt ccgcgcccgt aatttggcat tttccgcttg ttcgaggatt gccagcgcgt
    38521 cctggagaaa acattctccc gccgccgtca acgcgacttt gcgcttatcc ctcaccagta
    38581 acggaacacc gacacagttt tcaagatcgc ggatctggct gcttaacgaa ggctgtgagg
    38641 tatgcagttt ttccgccgca cgggtaaagt tcagtgcctg cgccactgcg acgaaatagc
    38701 gtaaatgccg tagttccatc accttcccct tgttatcgaa aaaacgtctc agctggtaga
    38761 aattaactat ttcacatatt agcaaccaac cagcaacatc cttatggcac aaaaatagaa
    38821 ggtcaataca tcttatcttt caggattaaa aaatatgacc acaccctcag atttgaacat
    38881 ttaccaactg attgataccc aaaatggtcg ggtcactccg cgtatttata ccgacccaga
    38941 tatttaccaa ctggagcttg aacgtatttt cggccgttgc tggctatttc tcgcccacga
    39001 aagccagatc ccaaaacctg gtgatttctt taacacctac atgggggaag atgcggttgt
    39061 cgtagtgcgt cagaaagacg gcagcatcaa ggcgtttctc aaccaatgcc gccaccgggc
    39121 catgcgtgtg agttatgcag attgcggcaa cactcgcgcc tttacctgcc cgtatcacgg
    39181 ctggtcttat ggcattaacg gcgagttgat cgatgtaccg ctggaacctc gcgcctaccc
    39241 acaagggttg tgtaaatccc actggggact aaacgaagtt ccttgtgtgg agagttataa
    39301 agggctgatt tttggcaact gggataccag cgcaccgggc ctgcgtgatt acctgggtga
    39361 cattgcctgg tatctggatg gcatgctgga tcgtcgcgaa ggcggcaccg aaattgtcgg
    39421 cggcgtacaa aagtgggtga tcaactgtaa ctggaaattc ccggcagagc agttcgccag
    39481 tgaccagtat catgctctgt tcagccatgc ttctgccgtt caggtattag gggcgaaaga
    39541 tgatggcagc gataagcgcc tcggtgatgg acaaaccgcc cgcccggtgt gggaaaccgc
    39601 caaagatgcg ctgcaatttg gtcaggacgg tcacggtagc ggtttcttct ttactgaaaa
    39661 accggatgct aatgtctggg tcgatggcgc agtttcaagc tattaccgcg aaacctatgc
    39721 cgaagcagaa caacgtttag gtgaagttcg cgccctgcgc ctggcgggtc ataacaatat
    39781 attccccacg ctttcatggc taaacggcac tgccacactc cgcgtctggc atccgcgcgg
    39841 ccctgatcaa gttgaagtgt gggcgttctg tattactgac aaagccgcct ccgatgaagt
    39901 taaagccgct tttgaaaaca gcgccactcg tgcttttggt cctgctggtt ttctcgagca
    39961 ggatgactcg gagaactggt gtgaaatcca gaaattgctt aaaggccacc gcgcccgcaa
    40021 cagcaaactg tgtctggaaa tggggcttgg tcaggaaaag cgccgcgacg acggcattcc
    40081 tggcattact aactatatct tttcagaaac tgccgctcgt ggaatgtacc aacgctgggc
    40141 cgatcttctg agtagcgaaa gctggcagga agtgctcgat aaaaccgctg cttaccagca
    40201 ggaggtgatg aaatgagtgc gcaagtttca ctagagttac atcaccgcat tagccagttt
    40261 ctctttcacg aagccagctt actggacgac tggaaatttc gtgactggct ggcgcagctc
    40321 gacgaagaga ttcgttacac catgcgcacc acagttaacg cgcaaacacg cgaccgccgc
    40381 aaaggcgtcc agccaccgac aacctggatt tttaatgaca ccaaagacca gctggagcgg
    40441 cgaatcgccc gtctggaaac gggcatggcc tgggcagaag agccgccgtc acgcacccgt
    40501 cacttaatca gcaactgcca gataagcgaa accgacatcc caaacgtatt tgctgtgcgg
    40561 gtaaattatc tgctttatcg ggcacaaaaa gagcgcgatg aaacattcta tgttggaacg
    40621 cgtttcgaca aagttcgccg tctggaagat gacaactggc gcttgctgga acgggatatc
    40681 gtcctggatc aagcggtaat cacttcccat aacctgagtg tactgttctg atgaatcgaa
    40741 tttatgcgtg tcccgttgcg gatgtgccgg agggtgaggc tctccggatc gatacctcgc
    40801 ccgtcatcgc cctgttcaac gttggcggcg agttttatgc cattaacgat cgttgcagcc
    40861 atggtaatgc gtcgatgtca gaagggtatc tggaagatga cgccacggtg gagtgcccgc
    40921 tacacgccgc cagtttttgc ctgaaaacgg ggaaagcgtt atgcctgccc gccaccgatc
    40981 cgctcaccac ttatccagta cacgttgaag gtggtgacat tttcatcgac ttaccggagg
    41041 cgcagccatg agcgatctgc ataacgagtc catttttatt accggcggcg gatcgggatt
    41101 agggctggcg ctggtcgagc gatttatcga agaaggcgcg caggttgcca cgctggaact
    41161 gtcggcggca aaagtcgcca gtctgcgtca gcgatttggc gaacatattc tggcggtgga
    41221 aggtaacgtg acctgttatg ccgattatca acgcgcggtc gatcagatcc tgactcgttc
    41281 cggcaagctg gattgtttta tcggcaatgc aggcatctgg gatcacaatg cctcactggt
    41341 taatactccc gcagagacgc tcgaaaccgg cttccacgag ctgtttaacg tcaacgtact
    41401 cggttacctg ctgggcgcaa aagcctgcgc tccggcgtta atcgccagtg aaggcagcat
    41461 gattttcaca ctgtcaaatg ccgcctggta tcctggcggc ggtggcccgc tgtacaccgc
    41521 cagtaaacat gccgcaaccg gacttattcg ccaactggct tatgaactgg caccgaaagt
    41581 gcgggtgaat ggcgtcggcc cgtgtggtat ggccagcgac ctgcgcggcc cacaggcgct
    41641 cgggcaaagt gaaacctcga taatgcagtc tctgacgccg gagaaaattg ccgccatttt
    41701 accgctgcaa tttttcccgc aaccggcgga ttttacgggt ccgtatgtga tgttggcatc
    41761 gcggcgcaat aatcgcgcat taagcggtgt gatgatcaac gctgatgcgg gtttagcgat
    41821 tcgcggcatt cgccacgtag cggctgggct ggatctttaa ggaagcacga tgaaagaaaa
    41881 aaccatcatt attgtcggtg gcgggcaagc ggcggcaatg gctgcggcct cgctacgcca
    41941 gcaagggttc accggtgagc tgcatctgtt ttccgatgag cgacatcttc cttatgaacg
    42001 acctccactc tcgaaatcca tgttgctgga agattccccg cagttacagc aggtgttacc
    42061 cgctaactgg tggcaggaaa acaatgttca tctgcattcc ggtgtaacca tcaaaacgct
    42121 gggtcgcgac acacgagagt tagtgttaac caacggcgaa agctggcact gggatcagct
    42181 ttttatagca accggcgcgg cagctcgacc gctgccgttg cttgatgcac tgggagaacg
    42241 ctgctttacc ctacgccatg ccggtgatgc cgccagactg cgagaagttc tgcagcccga
    42301 acggtcagtc gtgattgtcg gtgccggaac tattggtctg gaactggctg ccagcgccac
    42361 gcagcgcaga tgtaaggtga cagtgattga actggcggca accgtcatgg gccgtaatgc
    42421 accaccgccc gtgcaacgct atcttttaca gcgccaccag caggctggtg tgcgcattct
    42481 gctcaataat gccattgaac atgtggtcga tggtgaaaaa gtagaactga cgctgcaaag
    42541 tggggaaacg cttcaggctg atgtggtgat ttacggtatt ggtatcagcg ccaacgagca
    42601 actggctcgc gaggccaacc ttgatactgc caatggcatt gtcattgatg aggcttgccg
    42661 cacctgcgat cccgcgatct ttgccggtgg cgatgtggca atcactcgtc ttgataatgg
    42721 tgcactacac cgctgcgaaa gctgggaaaa cgccaataac caggcgcaaa ttgccgctgc
    42781 cgcaatgtta gggctaccgc taccgctact gccgccgccg tggttctgga gcgatcagta
    42841 cagtgataac ttacagttta ttggcgatat gcgtggcgat gactggcttt gtcgtggcaa
    42901 cccggaaact cagaaggcga tttggtttaa tctgcaaaac ggcgtgctta tcggtgcggt
    42961 cacgctgaat caggggcgtg agattcgccc aattcgcaaa tggatccaga gcggcaaaac
    43021 gtttgatgcg aaactgctga tagatgagaa catcgcgctt aaatcactgt aaccaggata
    43081 attagcgaat atctcaatgc ctggggcgtg gcgaggtgca agagtgtgta ttacgtttaa
    43141 atcacattat cttgcaaagg gattggttat gaacacacta cgttattttg attttggagc
    43201 tgcccgcccc gttttgttat taattgcccg tatcgccgtg gtcttaattt tcattatttt
    43261 tggttttccc aaaatgatgg gctttgacgg tacggtccaa tatatggcct cgttgggcgc
    43321 gccaatgccg atgctggcag cgattattgc ggtagttatg gaagtgcccg ccgcgatatt
    43381 aatcgtgctt ggctttttca cccgtccgct ggcggtgctg tttattttct acacgctggg
    43441 tacggcggtg attggtcacc attactggga tatgaccggc gatgcggttg ggccaaatct
    43501 gattaatttc tggaagaatg tcagtatcgc tggcgcgttc ttgctattgg caattaccgg
    43561 gccgggggca atttctctcg atcggcgtta ggaaagatgc cggatgcggc gtgaacgcct
    43621 tatccggcat tttataaatt acagccactc tacccgcaac gacatctctg aggttgttga
    43681 ttcccctggt gctagcgcaa tgagatcacc cccttccggg cgatgatgat catccggcgc
    43741 atggctcatc ggttccagac agaagaaatc aaacgcatat cctttatcaa acgcagggtc
    43801 ggaaacaaag atgaaataac acggtgcagg tggcgtcgtt tccatgatga tggcataacc
    43861 ttcctgcggc tgctcgatgc gggcctgacc attccatccg gcaaaaccat tgttcaccca
    43921 ctggcgcggc aacggcgcga gctggttaaa atccagttcc tgcggtagct gctcgcaaaa
    43981 ctcacccgcc agccactgct cccgttccag ccagtaaccg ctcgcctgtg cctgaatccg
    44041 cgtttgcggc gacaacggaa aataaggatg ccagccggta ccaaatggca gcgtctctgc
    44101 cccttgattg gtgacagaga gcgtcaccat cagcgtatcc gccgttaaat gaaacgcctg
    44161 acttacccga tagtgataga caccgctgcg atgttcatac accagacaca aactatcatc
    44221 gctgtgcgag acacattgcc actcgcccag ccagccatcg ccgtgtagat agtgcgcatc
    44281 ccactcaaca ttcggttgca gttgatactc acgcccctgc cagacaaaac gattgccgct
    44341 cacccggttt gcaaatggta ccagcggaaa acatgaggca tcggttgcca caccgctttt
    44401 tttaccagga cgtaagagcg gcgtcgtatc gcgccagaag ccttcgatta cgccgccctg
    44461 gtcagaaacg tccagcttta gcgacccgtg ggataaggta tagatggtca tccgctaact
    44521 ccttaatccg ggaagttaat cacaactttc ccgcatttgc cgctcgccat cagcgcatag
    44581 gcatcacctg cctgttccag cgagaagcga tgggtaatgg cgttacgcgg ccacagcttc
    44641 cagtccgtca gatcatgggc gcatttttcc atatggaaca gactggtcac ccaggagccg
    44701 ataatccgcc gttgatggtg catcagatcg gcgctgacct cgaattccac ttttccggtt
    44761 tcaccaatgt aaaccacccg tccccagtca gcagtggatt gcagtgccag caagcgacct
    44821 gcggcattac cggaacaatc gagcgcaaca tccgcgccac cgtgggtaag ttcagcaatt
    44881 atctgcggca gaccttcggt ggtcgctaaa tagccgtgat ccatcacccc taactgtttt
    44941 gccatcgcca gacgttccgg cagcatatca acgccgatga tccgttttgc accgcgacct
    45001 ttcgccagca tcatcgccat catgccgacc ggccccagac cgaccaccag cacgttatcg
    45061 ctgccggaaa cttcgccgcg caaaatccct tcataggccg tgccaacgcc gcaactgata
    45121 aacgcaccat cttcgtagct cagcgcatcc ggcaggagga tcagatcttt ttcttccgcc
    45181 agcagatatt cggcatgacc gccgtcacgc tgccagccgt aagccgcttt tcctttgcca
    45241 gtacaagaga taggaaagcc gcggcggcag ttcgggcaaa aaccacagcc agaaatgtga
    45301 tacaccagca cgcggtcgcc ctctttaaaa tggcggcagc cttgccccat cgccacaatc
    45361 tgcccgcacg gttcatgacc gttgataaat ccctggtata acggtttatc gggtgccgcc
    45421 gccgtggcac ggtgttgatg atagatatag tggacatcgc ttccgcaaat cccggaggat
    45481 ttcattttga tcagtacctg gttaatcccc ggcgtcggca ccgcaacttc ccgcagatcg
    45541 acggttgaat ttcctggtaa ataagctgcc agcatcgttt tcataaatcc ctcattaaca
    45601 atacgattaa ttttcatccc tgccgcaccc gcgccagggg cgttaaggtt tagcgtttcg
    45661 ctttactgct tcgctgggtc agcaagatat tcgccagcac cgccaccacg atgatgacgc
    45721 cgcgtaccac ctgctggaaa aaggagttaa taccgagcag caccagaccg ttaccgatta
    45781 gcgtaatcac cagcacacca agcaatgtac cgaacaggga accgcgaccg ccggaaagtg
    45841 ccgtaccgcc gaccacgacc gcggcgatga cgtcaaactc cagaccgttt gcggcacctg
    45901 cgttaccaga accgaggcgc gccgccaaca aaatgccggt caccgccgct aataatcccg
    45961 aaagggtaaa gataagaatg cgcacccgac gaacgttgat gccgcacaac tgcgccgccg
    46021 tagcattacc gccaacggca aaaaccgagc gcccgaaggc ggttttgcgg ctgatgaaca
    46081 caaacagcgc aaacaacaca atcatgatca gcgcggatac tggcacaccg agaaattgtc
    46141 cgcccagcca gtccagcacc tcgttttcgt caatcggcac tggcagtgcg ttggtcataa
    46201 acagccccat tccgcacagg gcgctccaca gccccagtgt ggcaacgaaa cttggtacgt
    46261 taaacacgcc gcgcagcacc ccggcgagcg ttcccatcag cgcgcctaac agcaacacca
    46321 gcagacaagc aatcgccaac ggaacttcaa attgcagcaa aaatgccagg cacaccgaga
    46381 caaaagccac catcggccca acgctgacat caatttcacc ggagataata atcagcgtca
    46441 tcgcccaggc ggcaatccca atggtggcgg catcgcgcag cacgttcatc tggttattca
    46501 atgagataaa gccaggcgcg ttcagggaga agaccagata aagaatggca atcaccacca
    46561 gcaaaccgat ctcattaata tggcgactga caaattgttt gagcgagacg ctcttgccct
    46621 gcggcaatgg taatgacgaa gcagacatct tcaggttcct cggtaaaatt catcagtgca
    46681 cagacagaat ggcggacatc agctcatcca cattgaccgg cgagtgaaac tcctgcgaga
    46741 acgtgccgtg ctgtaataac aggatgcggt cacacaccag cggcaactcc tccacttcac
    46801 tggagataaa caccacgctt tttccttcgg cagccagctc acggacaata cggtaaatct
    46861 gctgtttggc ttcgatatcg acgccgcgcg ttggctcgtc gagcaacaaa atctggctgg
    46921 cggcatagac ccaacgaccg atcaccactt tttgctgatt gccaccagaa agcgtgccga
    46981 tgggtgtttc gctactggca gccttgaccg tcatccgctg catcacctct tcggtcaggc
    47041 ggcggatggt ggaccattgc agcacaccgt tggtgctgat tttttgccga ttggtcagca
    47101 ctgtattttc gtcaacgccc agccagggaa tgatccccgc ttctttgcgg ttttctggcg
    47161 tatagccaat gccgcgtttc agcatgtcgc cgtaatcggg gcgcatgatt ttctcgccgt
    47221 tgataacaat ttcgccctgt tcatacgtct ccagcccaac aatcgccttc agcaattcac
    47281 tgcgccctgc ccccagcagg ccagcaatgc caagcacttc gccgcgacgt aacgtaaagc
    47341 tgatatcctc cagcttgggc ttatggcgta atgcacggac ttccagcacg gcctgatcga
    47401 caatttcctg aggggctacc ggcgcaatat caacgtgatc gcgccctagc attagcgaca
    47461 caatatgatg cgtggaggtg ttttcgagca tcacatcgcc cgccacctga ccatcgcgca
    47521 taacggtggc acaggaggca atgcggcgaa tttcttccat ccggtggctg acataaatca
    47581 ccgccacgcc cagtgccgac atctttttca ccgcgctgat caccagttca acttccgcac
    47641 tggcaagcga actcgtaggt tcatcaagaa tgaccacgcg cggctcgccc ttcatcaccc
    47701 gtgcaatttc caccagttgc ttttgcgccg ggcttagcgt tgaaacaagt tgttcaggac
    47761 taacgtcaac gcccagcgcc tgtaagcaac gttgggcatc ctgcgccatt tgcaggtaat
    47821 caatcatgcc gttgcggcgg ggccactgac cgaggcagag gttttccgcc accgtcagcc
    47881 cttccaccag acttaactcc tgataaaccg cacgaacccc cagttcagcg gcacggcgag
    47941 tcaacgtagc ttcgtcacct tccagtcgcg tctcgccaat ccagatatca ccgctatccg
    48001 ggcgttcact gccggtaagc attcgaatga gagtcgattt gcccgcgccg tttttaccta
    48061 acagcgcacg aacttcgcct ttattgagcg tgaagttaac gttatccagc gcaacgacgc
    48121 cggggtaacg cttatttcct gccaccactt ttgctaccgg gactgcctct gttgccgtga
    48181 acatagggac ctctgcgaat cagcgattag ggcagaccat caacgtgcgt tgccagccac
    48241 tgtttaccat cttccgtttt ggtatagaga tcgattggca cctgaatcac tttttcaccg
    48301 tcggcttgtt tattgataac cttcaatgtt tgcgcgagaa cagcattgcc cattttctta
    48361 ccggaaatat ccactaccgc tttcagcacc tgattgtttt ccagctcctg agcaatttca
    48421 gtggtcatat ccgaaccgaa aacagcaatt tttccggcct gattttgatt acgtaccgct
    48481 tttaccgcgc cgagtgtcgc tccgcccgat tcacccataa tggcgttgag atccggcgtg
    48541 gagataatta gtttttcacc aacggaaatc gctttatcta aaacagtccc ttcctgatta
    48601 gcgacaattt gcgcgccggg aacgcgggat tttaatactt cttcaaatcc tttacgtcgc
    48661 tgcacacaaa cttcaaaggc ttcgcaattg atgacggcaa ttttcggctg gtcaatttta
    48721 ttggcaataa aataatcggc ggcagcatta cccagttttt taccaaattc cagcggatcg
    48781 ccgaccagat acgccgagac atatttatcg acaccctttt gattaataca ggtgttgtag
    48841 caaatcaccg gaatacccgc ttcactggcg cgacgaacgg tacggctact gccattttca
    48901 gacactgccg ataaaataat ggcatcgaca ttacgcgcca cgagggtatc aacaaaggta
    48961 ctttctttcg aaatatcacc ctgggcgtta gtttcaatta actgtacctg tactgaagaa
    49021 tcttttgccg catcctgaac gccttgacgc actccagcgt aatatccctg agtatcaagg
    49081 tatattgcgc caatggtcat ttctttttcc gcagccctgg caaataaagc gctacctaat
    49141 agcgtagcca ttaataatag attacgggtt gttctcattt ttttaggcat agagcctcct
    49201 gtagggtttt tattaacaac ggcttattct aattattttg tgatgagcgg cagcgcgtgc
    49261 cgctcaaata ttacagttaa tagggtttag tgaacgtagt taaaaataaa aggcatcaca
    49321 gtggtgaata atgccgcttt cggccaggcc ggattaatcg ccgtcaattc agcgcgagca
    49381 gactcatatt gcgcaacctc cccgagtccc gcggacgcca gcatcgccac catcaggcat
    49441 ttttctttat gctgctgttg taaatcgcca tacagcgaca acagatcagg ttgtgaaaca
    49501 gcaaagaaat ccgcctcaat actggttttc gccatctctt gcgcccactg tttcatttca
    49561 ctaaacagtt gctgtgcggt gtgttgttcg cccagcagtc gcagcgccat tccttgccag
    49621 aagagataat caaccggctg atcgttgtaa taactgtgga tgttaatggt gcgatcgccg
    49681 gtcgccgcca gacgtaaaca acgcatcgct tcagtttcat cgccctgcgc gttggcgcat
    49741 atcgcctgcc agaaccagat gtcgttatca gtttgccccg gtaaacggcc ttcgcttaaa
    49801 ttctccggat aatgcagcgc ggcatgaagc agttcgctgg cctgctgcgg ctgtctggca
    49861 tcaaggtgct gccaggcgcg taataactgg ttgaggataa actgactggt gaccttccct
    49921 tccccgcctt cccacgggtg gaatttgcgc gtggcgagaa tgtccgccgc tttgtctgcc
    49981 tgacccgtga gatgccacaa attgagcaac tctgctgtca tgtcgtcgcg tttcagcgca
    50041 atttccagat tattttccag acgcgccagt cgtttctccg gtgtggctcc gcttaactta
    50101 tcaagcaaat cccgttcgaa aagcagacgt gcatcctgcg gcgcaagctg ataagcatta
    50161 tcaagataac gcgcggccag ctcataatcg tgttgcttat tccacgcatg gatcgctaac
    50221 ccgcgccagc cgtcggcaaa ctccggcgac atctctacgc aacgttgcca taaagtaatg
    50281 gctttgttgt agctgcgctt gttgtagtag aagcaggcca gtaaatgacg ggcaaaccag
    50341 cactcttcaa tactctccag cgccgccact tcttccagcg tattcgggaa acggacaaac
    50401 tgcgggaaga catcaatggc ttttgcgacc agttcgccgc gttcggcttt cggcagcaag
    50461 ctggcttgta gataaagcga taacgtgcgc tgacagtcca gtgcgttcag catctctgtc
    50521 gccagagtgg gcattcccca gttaatcagt tgcccggcgg tcatcagggc gttaacgtcg
    50581 cgtccctgac acagaccgcg ccactgcgcg agagctgatt cgctacgacc atcgaaccag
    50641 ttcagccacc acagagtggc gttcagcgga taatcgcgca gcagtttctc gcgctgcaca
    50701 cgcgcgttgt cctgacgacc acttaacacc agcagcagat tatgcaggca aagcacttcc
    50761 tgattggttg ggcaggcgcg aagactttgt tggcaaaaat ccagaccagc gtcgaagtta
    50821 ccattacgcg ccgccagtcg tgccaggcca taatagccac cggctttgct gttgccgctc
    50881 cagaccgcac gccagaaatc ctcttcggct tgttgatatt gtccctgacg ttcgtaagca
    50941 ctggcgcgaa tcaaactcgc ctgtccgcac tgcggatttt tgttcagcgc atgtgcgcgt
    51001 ttcagagcct gagtggcata cgccaccgct tgcgggaaat cggcacggtt atattccagc
    51061 atcgccagcg ccaggttaca gcggtaatcc agcggatcca gcgccacgcc gcgcaggtag
    51121 taatcgaacg gtgaacggct ggcgtgatga tattgctcca gatgctgacc gataaaccag
    51181 gcttcatctg tactggtaat gtcttgtgct gacagtggcg ctttggcgac gtccggcaac
    51241 ggcaactctt gcggctgatg ttcctgataa ctcagtacaa tattgccgtc ggcatcggag
    51301 agctcaatgg tcagcctttc aggattgata ccgtgcaaca cgccctggat ggcggtcgca
    51361 ggcatcagtg ccacggcatc atcaagtaac gcgttgcatt tgccgatttc gcggatcgcc
    51421 aggcggtatc cgttcaacgg agagatggca tacagccccc actcaatccc ccgctcacta
    51481 cgctggagtt ttatcaccgc atcgcgggag gcattttgca ccatgcccaa agaatgataa
    51541 ggcaggaaat actgctcaaa acgcttctct tcgtaagcat caagccaggt aaaatcaggc
    51601 tggttatcgg caaaaatacc ggtcatcagt tcgatatacg ggccgttatt gtcggtcaga
    51661 ctcttgtccc acgcctggcc gaattcactg tgtccccagc tccactgttt tttacctggc
    51721 gcgatatggt ggttggcaac gtgtagcaaa ccgccatctt catcgtgaca ccacgcgcca
    51781 acaaaatcgt actgtgattt ttcagccata tatgaggttg gaacgggcac atttttatag
    51841 cgagaaatgt ccactccggc ggagtagtcc actttgtagt aagtgccggt ggcgatgggg
    51901 aaagcggaga cggcccgttt gccgtgatca aacaccgccg ttacatccgg cgggaagacg
    51961 ctctgatgcc cttccccccc tttcactgcc gggttggccc accacaagaa atgacgcggc
    52021 gtggcgttgc cgttatagac gcggctggca atttccaacg ccgcccgttc aggacgcagt
    52081 gtgaaacctg tcatcacctg taaaccgtgc atcggctccg tttcgccgac ccacaccgtc
    52141 tgtgcgccgt cttcatgggc ttcgagggtg aaatcaacgg gcataaaggt ggtcgggcga
    52201 tggtgttgcg gccagttaaa ctcaatcccg ccagagatcc acggtcccag cagccccacc
    52261 agcgcaggtt taatgacttc attgtgatag acaaaatcgc gttgtttcac tttatcccat
    52321 gcgcgatgca cacgaccgcc cagttccggc aggatcatca ctttgatgta gtcgttttcc
    52381 agccacaccg cctgccagga tttcagggtt ttctgctcgc tcagcgtatc ggtcacgccg
    52441 tagggataaa ccgcgccgga cgatccctga taaacgcgat tttccaggaa catgggatgt
    52501 atatcctgcg gcccggtttc ataggtcggg atctcaacgc gctcttgcca cacttttact
    52561 ggagtcatgg tgccctcaat attaacaaga catactgaat taaaagattt gtggcagtgt
    52621 attgaacaat ctggcaatgt tttcgcggaa taatcacgca attaactaaa caaggtttag
    52681 tgaagatgag agcctgcatt aacaatcaac agattcgcca ccataacaaa tgcgtgattc
    52741 tggaactgct gtaccggcaa aagcgcgcca ataaatcaac gctggcccgg ctggcgcaaa
    52801 tttcgattcc ggcagtcagt aatattttgc aggaactgga aagcgaaaaa cgggtggtga
    52861 atatcgacga tgaaagccag acgcgcgggc atagtagcgg tacatggctg attgcgccgg
    52921 aaggtgactg gacgctgtgc ctgaacgtga cgcccaccag tattgagtgt caggttgcta
    52981 atgcttgttt aagtccgaaa ggcgaatttg agtatttaca gattgatgta ccgacgccgc
    53041 aggcgctgct gtccgaaatc gaaaaatgct ggcatcgcca ccgtaaattg tggccggacc
    53101 gcaccatcaa tctggcgctg gcaatccacg gtcaggttga tccagtgaca ggagtgtcgc
    53161 aaaccatgcc gcaagcgccg tggacaacgc cggttgaggt gaagtatctg ctggaagaga
    53221 agctgggcat tcgggtgatg gtcgataatg actgcgtgat gctggcgctg gcggaaaaat
    53281 ggcaaaataa ttcgcaggaa cgggatttct gcgtgatcaa cgttgattac ggcattggct
    53341 cgtcgttcgt gattaacgag caaatttatc gcggcagttt gtatggtagc ggacagattg
    53401 gtcacaccat cgttaatccg gatggcgtcg tctgcgactg tggacgttac ggctgcctgg
    53461 aaaccgtcgc ctcgttaagc gcattaaaaa aacaggcgcg ggtatggcta aaatcacaac
    53521 cggttaatac tcagcttgat cctgaaaaat tgactaccgc gcagttaatc gctgcctggc
    53581 agagtggaga accgtggatc accagctggg ttgaccgcag tgccaatgcc attggtttga
    53641 gtctgtataa cttcctcaac atcctcaata ttaatcagat ttggttgtac ggtcgcagtt
    53701 gtgcctttgg tgagaactgg cttaatacta ttattcgcca gacgggattt aacccgttcg
    53761 accgcgacga aggaccgagc gtgaaagcga cgcaaattgg cttcgggcaa ttaagccgcg
    53821 cacaacaggt gctgggaatt ggctatttgt atgttgaggc gcagttacga cagatttgat
    53881 ggcgcgataa cgtagaaagg cttcccgaag gaagcctttt ttcaacagat taaccgtttc
    53941 gcttatgcgt aaaccgggta acgtgcgcag atgtcgagaa ctttaccttt gatgcgctcg
    54001 ataacggctt catcattgat gctgtccagc acgtcacaca tccagccagc cagttctttc
    54061 gcttctgctt ctttgaagcc gcgacgcgta attgccggag tacccacgcg aataccggag
    54121 gtcacaaacg ggctcttcgg atcgttcggt acgctgtttt tgttgacggt gatgttagca
    54181 cggcccagag cggcgtctgc ttctttaccg gtcaggtttt tatcaaccag atcaaccagg
    54241 aacaggtggt tatcagtgcc gccggaaacc actttgtagc cgcgttccag gaacacttct
    54301 accatcgctt tagcgttttt agcgacctgc tgctggtaag ttttgaactc aggctccatc
    54361 gcttctttca gagcaaccgc tttaccggcg attacgtgca tcaacggacc gccctgacca
    54421 ccagggaaaa cggcagagtt cagttttttg tacagctctt cgctaccacc tttcgccagg
    54481 atcaggccgc cgcgcggacc cgccagggtt ttgtgagtgg tggtagtaac aacgtgagca
    54541 tgaggaaccg ggttcgggta gacgccagca gcaaccaggc ccgcaacgtg cgccatatca
    54601 acgaacaggt aagcaccgat gctgtcagcg atttcacgca ttttcgccca gtcaaccacg
    54661 ccggaatatg cagagaaacc accgataatc attttcggct tgtgttcttt ggcttgtttt
    54721 tccagatcgg cgtagtcgat atgaccggta gcatcgatac cgtaaggaac gatgttgtac
    54781 agtttaccgg agaagttaac cggagaaccg tgagtcaggt gaccgccatg cgccaggttc
    54841 atacccagaa cggtatcacc tggttccagc agcgcggtgt agaccgcaaa gttagcctgg
    54901 gagccggagt gcggctggac gttagcgtag tcagcgccga acagttcttt cgcacgatcg
    54961 atcgccagtt gttcaacgat atcaacatac tcgcaaccgc cgtagtagcg tttgcccgga
    55021 taaccttcag catatttgtt ggtcagctga gaaccctgcg cctgcattac gcgcgggctg
    55081 gtgtagtttt cggaggcgat cagttcgatg tgctcttcct gacgtacttt ttcctgctcc
    55141 atagcctgcc acagttcggc atcataatcg gcaatgttca tttcacgctt taacatccgc
    55201 atctcctgac tcagctaaca ataaaatttt tggcctttat aggcggtcct gttggacaac
    55261 ggcgaacagt ataaccgaat cattgtgcga taacaggtct tgacaaagga atttacgcaa
    55321 acgattacct tcaggctacg caaggctttg gagaataaag agcttgcaac cggaaacgga
    55381 tttcttttca ggtttgtgat gcaaattttt cacttcatca cattctttct gaaaaacacc
    55441 aaagaaccat ttacattgca gggctatttt ttataagatg catttgagat acatcaatta
    55501 agatgcaaaa aaaggaagac catatgcttg acgctcaaac catcgctaca gtaaaagcca
    55561 ccatcccttt actggtggaa acggggccaa agttaaccgc ccatttctac gaccgtatgt
    55621 ttactcataa cccagaactc aaagaaattt ttaacatgag taaccagcgt aatggcgatc
    55681 aacgtgaagc actgtttaac gctattgccg cctacgccag taatattgaa aacctgcctg
    55741 cgctgctgcc agcggtagaa aaaatcgcgc agaagcacac cagcttccag atcaaaccgg
    55801 aacagtacaa catcgtcggt gaacacctgt tggcaacgct ggacgaaatg ttcagcccgg
    55861 ggcaggaagt gctggacgcg tggggtaaag cctatggtgt actggctaat gtatttatca
    55921 atcgcgaggc ggaaatctat aacgaaaacg ccagcaaagc cggtggttgg gaaggtactc
    55981 gcgatttccg cattgtggct aaaacaccgc gcagcgcgct tatcaccagc ttcgaactgg
    56041 agccggtcga cggtggcgca gtggcagaat accgtccggg gcaatatctc ggcgtctggc
    56101 tgaagccgga aggtttcccg catcaggaaa ttcgtcagta ctctttgact cgcaaaccgg
    56161 atggcaaagg ctatcgtatt gcggtgaaac gcgaagaggg tgggcaggta tccaactggt
    56221 tgcacaatca cgccaatgtt ggcgatgtcg tgaaactggt tgctccggca ggtgatttct
    56281 ttatggctgt cgcagatgac acaccagtga cgttaatctc tgccggtgtt ggtcaaacgc
    56341 caatgctggc aatgctcgac acgctggcaa aagcaggcca cacagcacaa gtgaactggt
    56401 tccatgcggc agaaaatggc gatgttcacg cctttgccga tgaagttaag gaactggggc
    56461 agtcactgcc gcgctttacc gcgcacacct ggtatcgtca gccgagcgaa gccgatcgcg
    56521 ctaaaggtca gtttgatagc gaaggtctga tggatttgag caaactggaa ggtgcgttca
    56581 gcgatccgac aatgcagttc tatctctgcg gcccggttgg cttcatgcag tttaccgcga
    56641 aacagttagt ggatctgggc gtgaagcagg aaaacattca ttacgaatgc tttggcccgc
    56701 ataaggtgct gtaatttgat gttgccggat ggaaacatcc ggcaaccctt gacgcggttt
    56761 aaattgccgc gtcgtcctct tcaccggtac ggatgcgaat gacccgtgcc acgtcaaaga
    56821 cgaagatttt accgtcaccg attttgccgg tttgcgccgt gcgaataatg gtatcgacac
    56881 aggtatcgac aatgtcgtcc ggtacgacaa tctcaatttt cactttcggc agaaaatcca
    56941 ccatatactc cgcgccgcgg tacagctcgg tatggccttt ctggcgacca aagcctttca
    57001 cttcggtcac cgtcatgccg gtaataccga cttcggccag tgcttcgcgg acatcgtcca
    57061 gcttgaaggg ttttataatc gcatcaatct ttttcatgct attccttgaa aaggtcgcct
    57121 gtcttttgat ctgctaaacg taacacataa cgccaattca ttccttgaaa tcgtttgcat
    57181 ccagctcgtg tcgggaaagc agtttataaa attctgtccg gttgcgcccc gccattctcg
    57241 ccgcgtgggt gacgttgcct ttggtaattt gcagcagctt acgcaaatag ttgagttcaa
    57301 actgattacg tgcctcaaca aaggttggca gcgccgtgtt ttcaccctcc agcgcctgct
    57361 ctactaatgc atcgctaata accggagatg aggtcagcgc cacgcactgt tcaatcacgt
    57421 tgaccaactg gcgcacatta cccggccagc tagcggtcat caggcgtttc atcgcatcag
    57481 tggagaacgc gcggacaaac ggtttatgtc gctctgccgc ctggcgcaac aggtgatttg
    57541 ccagaagcgg aatgtcttct gtgcgctctg ccagagccgg aattttcagg ctgacaacgt
    57601 tgaggcggta atagagatct tcacggaatt ccccgcgcgc catcgctttt ggcaggtcgc
    57661 ggtgagtggc ggaaataatc cgcacgtcga tatcaatatc gcggttgctg cccagcgggc
    57721 gcactttacg ctcctgcaac acgcgcagca gtttgacctg caatggtgcg ggcatatcgc
    57781 caatctcatc gagaaatagc gtaccgcctt ccgccgcctg gaataaacct tcgcgattgc
    57841 tgacagcgcc agtaaacgcg ccacgcgcat gaccaaacag ctccgactcc agcaactgct
    57901 cgggcaatgc gccacagtta atagcaataa atggtttgct gttacgcggg ctggcgttgt
    57961 ggatagcctg ggcgaaaatc tctttcccgg tgccgctctg gccattaatc aacacgctga
    58021 cgtctgattg cgccaccagc cgcgcctgtt ccagcaaacg cagcatcagc gggctgcggg
    58081 tgacaattgc ctcgcgccag cgttcatcgg tggctggcgc ggattgctcc agcgcatcgt
    58141 caattgcctg atatagcgcg tctttgtcga caggcttggt gaggaaacta aaaacgccct
    58201 gctgtgttgc agcaacggca tcggggatag aaccatgcgc agtaagaata attaccggca
    58261 ttcccggctg cactttctgg atttcagcaa acagctgcat accgtccatt tcatccatcc
    58321 gcaggtcgct gataactaaa tctacttttt cgcgattcag tacccgtaat ccttcagcgc
    58381 cactttccgc cgtgaccaca ctgtagcctt cgctggtcag gcgcaggcca agcagtttca
    58441 gcaatcccgg atcgtcatcg accaataata aatgcgcagg tttatggctc atcaggagtg
    58501 acctcatggg tggatggcgc gggcttttca ccctcgtgcg gcgtatccgg cgagaaattt
    58561 ccagccggtt tgcgggtcga gagctggcgt tcaatatcag tcaggttttc cagcttgcgg
    58621 gtggtgagtt ccagttgctg ctgtagaacg tgatgttgct ggcgcaatgt atccagctcg
    58681 ctgtcgctgg cctgctggag cttgccgtag cgttggcgct cttccgccag ttgcagttgc
    58741 agcgcctgac cgtcgcgcca gagttgatac agagggcgaa cctgtgccgg gatctcggta
    58801 cttagcgcat caatgcgcgc gaccagctgg cggcgctcat acggcgtaat tttggcgtcg
    58861 gcgagcaaaa tcccttgttt aaaggtattt tgccagctgc cgtcgtcata ttggcgagct
    58921 tgctgacgtg actgcgcagg cattaaacga tcagcacaat ccatcgcccg cagccagtaa
    58981 agcggattgg tttcggttga tttaccttgc agcgcccaga tgtcgctaca ttcagtagaa
    59041 agatagtcag ccagttgata aaccggaatt ttttcttctg ctggcgtatc aatggctggc
    59101 ttattgtgac tctgcacgca acccagcaat gccagacatg gcagccctgc cagccacagc
    59161 cgtcggggca ataatcgttg aaaaatgtgt cgcatattca ccagacttaa tgcctatccc
    59221 agtgggcgta attattgcag gcagtttgga catggacagc gcggagaaac cggagcgtac
    59281 acgtcgtacg tgaggatttc gagcactgcc cggggccgaa ctggcaaata aaatagcctg
    59341 atgggatagg ctgttagcat tatttcgtgt ttttcgacga cggcaattca atgcggaaac
    59401 aaacgtcttg cccgctctcg tcgaccagat acagttcccc ttgcatacgg cgaatacaat
    59461 ccctggcaat gcttaatccc agaccgctgc ccttcaccgc cccttttcgc tggtggcttc
    59521 cttgaaaaaa gggttcgaag atcatggcgc gttcctcttg cggaatgggt gtgcctgtat
    59581 tgatgacatc aatataaacc cgtgcaccat gtaagctgct gcgaaggcaa atgttaccgg
    59641 attcagcccc gtagtgcacc gcattggagt aaagattatc cagtacgctc atcagcagca
    59701 ttggctccgc caggcaagct gttgctttga gatcgacgtc ggtatgcatc attttagccc
    59761 gtgcgggcag gctatgagca gaaaccactg tctccaccag cggtgctaat tcaacattct
    59821 ccagttccac cgcactgtcc gcctgtttac ggttgtaatc aagcagttgt tcgatcagtt
    59881 tttgcaaatt gcggctgctg ctatcaagaa tgctcaccac ctctttttgc tctggcgtaa
    59941 gcggcccgac aacctggtca gccagtaatt cagtgccctc gcgcatactc gccagtggcg
    60001 tttttaattc atgagataaa tgtcttaaaa attgatggcg ttgggattcc agccatgaca
    60061 ggcgctcact taaccaaaga atacgttgcc caaccgagcg taactcgctc ggtccactga
    60121 acgaaacgct attgcccaga gaacgccctt cccccagacg gttgatcatg cgctcgatat
    60181 ttttcaccgg cccgataatc atccgcgtga aaagtagcac catcaccaga ctcaccagaa
    60241 atagcaccag cgattgccaa ccaaaatatt gcccacgttc ggcgatttca cgctgaagtt
    60301 gctgcccacg agagaacacc actgtgcgcg tggcctgcac catttcggta ttggcactgg
    60361 caaaggcttc aagacgcgcg gcggcggcag catcgggacc actgttgtta cactgaagtt
    60421 gggccagatt gttcaaatcc tgacgcaatg cctggtaaag tttatcgtct ggcagtacgc
    60481 ctgcgtgggc atcgagcatt tcgctgtaac gcttgcgctg gctttgataa accttcgcaa
    60541 gcgtaggatc gtccagcacg caatactgac ggtagctacg ctccatctcc agcgccgcgt
    60601 tggtcatcgc ttcactacgc cgggcatcaa taagcgtagt gcggttaacc agcgccgcct
    60661 gatcgctaag cgcattcagg ctttgccagg cttgccatgc cagcaccaac aggggtagta
    60721 gaattagcaa aaatgccagc attaccagtt gtcgtaatga gcggggaaaa acaggccagc
    60781 gtttcaaggt gttactctcg tcagacgcga atagcctgat gctaaccgag gggaagttca
    60841 gatacaacaa agccgggaat tacccggctt tgttatggaa taaggcggtg cctaactcga
    60901 cgtttcgccc gatggttgat atagctacgc tgatatcaga agttggacgg caggcacctt
    60961 gttgtgcgtc attcgaattt tatgtagcac gtcccgaagg ggctgacata agtcggtgaa
    61021 tgagccactg cttactatta tgcagtaact gtgccaataa agaaaatagt ttggtaacgt
    61081 actgattata cgtcgctttg aggggtttat ggcttctccg ttatttgaat gtaaatcagc
    61141 cactgtgtcg ctaaaaagag acaacttaag ataaatttat tagataatat taaaatcaat
    61201 gagttaagtg tcgccagaaa gcgacacgat aaaccaccca ttgtcgtgat ttacagacac
    61261 aaaaaagctc ccggagttgg gagcttatga tagtggttgg tgcttaatgc cggatgcggc
    61321 gtaaatgccg catccgggct gcaaaaccaa tgaactgatg acttacccca actgcttacg
    61381 cgcattgcgg aaaatgcgca tccatgggcc atcctcgccc cagttttccg gatgccagga
    61441 gttgctgaca gtacggaaaa cacgttccgg gtgcggcatc ataatggtga ctcgaccact
    61501 ttcagtcgta atcgacgtaa taccgttcgg tgaaccgttc gggttagccg ggtaggtttc
    61561 agtgactttg ccgaagttat cgacatagcg cagtgccacc agccctttgc tttccagtgc
    61621 cgccagatgc gccgcatcac gcacttccac gcgcccttca ccatgagaga cagcaatcgg
    61681 catttgcgag cccaccatcc cctgcaacag cagcgacggg ctttgggtca cttcaaccag
    61741 gctgaaacgc gcttcaaagc gatcggaggt attgcgcaca aaacgtggcc acaactcact
    61801 acctgggatc agttcgcgca ggttagacat catctggcaa ccgttacata cccccagcgc
    61861 cagcgtttgc ggacggtgga agaaggttgc aaactcatcg cgtacacggt cattgaacag
    61921 gattgacttc gcccaacctt caccggcacc cagcacatca ccgtaggaga aaccaccgca
    61981 cgcgaccagg gcgtggaaat cttccaggcc cgtgcgtcca gtcagcaggt cactcatatg
    62041 cacatcgatt gcatcgaagc ctgcacggtg gaaagctgcc gccatttcaa catgcgagtt
    62101 cacgccctgc tcacgcagca cagcaacttt cggacgtgcg ccagtggcaa tatacggtgc
    62161 tgccacatct tcgttgatat cgaacgacag tttcacattc aggcccggat cggcgtcgtt
    62221 tgatttcgcc tggtgctcct ggtcagcaca ctccgggttg tcacgcaggc gctgcatctg
    62281 ccaggtagtt tctgcccacc agacacgcaa cgtggtgcgg ctttcgctga atacagtctg
    62341 cccgttggcg gtaatcacaa aacggtcacc ggaaaccgcc tgccctacat aatggacaca
    62401 atcagcaagc ccatgctgtg ccagtacgga ctcgaccgct tcacggtcag cggcacgaac
    62461 ctgaatcacc gcacccagtt cttcgttaaa caacgccgcc aggcgatcgt cgcccagaga
    62521 ggcaatatcc gcgttaatgc cgcaatgacc agcaaaggcc atttccgcca gcgttaccag
    62581 caggccgcca tcagagcggt cgtggtatgc gagcagctta cgctgtgcaa ccagcgcctg
    62641 aatcgcgtca tagaagcctt tcagttgcgc gacatcgcgt acatctgccg gtttgtcgcc
    62701 aagctgacga taaacctgcg ccagcgccgt tgcgcccagc gcgttattgc ctttgcccaa
    62761 atcaatcagc agcagtgcgt tatcttcggt agaaagctgc ggcgtgatgg tgtgacgtac
    62821 atcttccacg cgggcaaatg cagaaatcac cagcgacagc ggcgacgtca tttcgcgctc
    62881 ttcgttacct tcctgccagc gggttttcat cgacatagag tctttaccca ccgggatcgt
    62941 caggcccagc gccggacaaa gctcttcgcc cacggcttta acggcttcat acaggcccgc
    63001 atcttcacca gggtggcctg ccgccgccat ccagttggcg gaaagtttaa tgcgtttgat
    63061 atcgccaatc tgtgttgcgg caatattggt taacgcttca ccgaccgcca gacgggcaga
    63121 ggcggcgaaa tccagcagcg caaccggcgc acgctcgcca atcgccatcg cttcaccgta
    63181 gtagctgtcg aggctggcgg tagtgaccgc gcagttagcg accggcacct gccacggacc
    63241 caccatctga tcgcgcgcta ccatgccagt tacgctgcgg tcaccgatgg tcaccaggaa
    63301 agttttctcc gccacggtcg gcagatgcag tacgcgtttc accgcgtctg caatggtgat
    63361 cccttcacgg accagcgcat cgcccttcgc tttcagcgtt tgtacatcgc gggtcatctt
    63421 cggcgtttta ccaagcagga cgtccagcgg cagatcgatc ggctgattat caaaatgacg
    63481 atcgtgcaga gaaagatgca gttcttcggt cgcttcacca atcaccgcgt agggtgcgcg
    63541 ctcacgctta cacagttcgt caaacagcgg taattgatcg gctgcaaccg ccagcacgta
    63601 gcgttcctgg gattcgttac accagatttc cagcgggctc atgcccggtt cgtcgcttag
    63661 aatatcgcgc agttcaaatt taccgccgcg tccgccgtcg ctcaccagct ccggcatcgc
    63721 gttagaaaga ccgcccgcac cgacgtcgtg gataaacaga attgggttag catcaccaag
    63781 ctgccagcaa cggtcgatca cttcctggca acgacgctcc atctccgggt tgtcgcgctg
    63841 tacggaagca aagtcgaggt cggcatcaga ctgacctgac gccatggaag acgccgctcc
    63901 gccgccaaga ccgatgttca ttgccgggcc gccgagaacg accagcttcg caccgacgtt
    63961 gatctcgcct ttttgtacgt gatcggcgcg aatgttgccg atcccgcccg ccagcatgat
    64021 cggtttgtga taaccgcgca gctcttcgcc gttgtggctg ttcacttttt cttcataagt
    64081 acggaagtag ccattcagtg ccggacgacc aaattcgttg ttaaacgccg cgccgcccag
    64141 cgggccttcg gtcatgatgt ccagcgcggt gacaatacgc tcaggcttac cgaaatcttc
    64201 ttcccacggc tgttcgaagc caggaattcg caggttggaa acggagaaac caaccaaacc
    64261 cgctttcggc ttcgcgccgc gcccggtggc accttcatcg cggatttcac cgccggaacc
    64321 ggtcgccgcg cccggccacg gagaaatcgc cgtcgggtgg ttgtgagttt cgactttcat
    64381 cagaatatgc gccggttcct gatggaaatc gtagcggccc gtttcgtggt cagcaaagta
    64441 gcggcccact tcagaacctt ccattacggc ggcgttatct ttataagcag agagaacgta
    64501 atctggcgtg gtttcgaagg tgtttttgat catcttaaac agcgatttcg gctgttgctc
    64561 accgtcgata acccaatcgg cgttaaaaat cttgtggcgg cagtgctcgg agttcgcctg
    64621 ggcgaacata tacagctcga tgtcgttcgg gttacgacca agctttgtga aagcatcctg
    64681 cagatagtca atttcatctt ccgccagtgc caggccaaga cgcaggttag cgtcgattag
    64741 cgcctgacgg ccctgcccca gcaaatcaac gctggtgacc ggagtcggtt gatggtgtgc
    64801 aaacagctgc tctgcatcat ctaaagcaaa aaagaccgtt tccatcatgc ggtcgtgcag
    64861 ttcagcggta acctgctgcc attgttcatt ggtcagcgta ccggcttcta tatagtaagc
    64921 aacgccgcgc tcaaggcggt ttacctgttg tagcccgcag ttatgggcaa tatcggtcgc
    64981 tttcgaagac cagggagaga tggtgccagg acgcggggtc accagcagga gtttgccttg
    65041 cggggcgtgg ctggcgagtg ccgggccata tttcagcagg cgttcaagtt gtgcgtgctc
    65101 atcatcgttt aacggcgcat tgaggtcagc aaaatggaca tactcggcgt aaatattgtg
    65161 aaccgggagc ctggcagcct gaaaacgtgc cagcagtttg ttgattcgga atgccgacag
    65221 tgcaggcgaa ccacgcagaa tttccatcat aagtctctcg tcttctaagc tttcggtgta
    65281 cccaaggggg ggaaacgggc gtcattataa agaatctgat gcgctgacga aaccgtttgc
    65341 gtggaaataa aatcaccatc gtgaattagc aacgcgtgcc gccaatggct gtaataagtt
    65401 gccatctggc gcaggtttac gcaaaatgcc gctcatttat gagtaaacct ttcactatta
    65461 ttacgttttt tcaagctggg acgcgcacga cacagagaat taactaattg aaaaaattaa
    65521 agattaatta tctgttcatc ggcattctgg cactgctgct cgcggtcgct ctctggccat
    65581 ccattccctg gtttggtaaa gccgacaacc gtatcgccgc cattcaagcg cggggagagt
    65641 tgcgtgtgag caccattcat actcccctga cttataacga aatcaacggg aaaccttttg
    65701 gcctggatta cgaactggcg aaacagtttg ccgattacct cggtgtaaaa ctgaaagtga
    65761 ccgtgcggca gaatatcagc cagctgtttg acgacctcga taatggtaac gccgacctgc
    65821 tggcggcagg actggtctat aacagtgagc gggtaaaaaa ttatcagcct ggccctacct
    65881 attattccgt gtcacaacaa ctggtttata aagtgggtca gtatcgcccg cgcacactgg
    65941 gcaacctgac ggcggagcaa ctcaccgttg caccgggtca cgtggtggtt aacgatctcc
    66001 aaaccctgaa agacacaaaa ttcccggaat taagctggaa ggtagacgac aaaaaaggct
    66061 ctgcggaatt aatggaagat gtcatcgaag gaaaactcga ttacaccatt gctgattctg
    66121 tcgccatcag cctgtttcag cgcgttcacc cggagctcgc cgtagcgctc gatatcaccg
    66181 atgaacaacc ggtgacttgg tttagcccgt tagatggcga taataccctt tccgccgccc
    66241 tgctcgactt cttcaacgaa atgaatgaag acggtacgct ggcacgcatt gaagagaaat
    66301 acctggggca tggcgatgat tttgattacg tcgatacgcg cacattttta cgcgccgtcg
    66361 atgcggtact gccgcagtta aagcccctgt ttgagaaata cgccgaagaa attgactggc
    66421 gtttgctggc cgctattgct tatcaggaat cgcactggga tgcacaggcc acttcaccga
    66481 cgggtgtgcg cggcatgatg atgttaacca aaaataccgc gcaaagcctc ggcattacgg
    66541 atcgtaccga tgccgaacag agcatcagcg gtggcgtgcg ttatttgcag gatatgatga
    66601 gtaaagtgcc ggaaagtgtg ccggagaacg agcggatctg gtttgccctc gctgcgtaca
    66661 atatgggcta tgcgcatatg ctggatgccc gcgccctgac ggcaaaaacc aaagggaatc
    66721 ctgacagttg ggctgacgta aaacagcgtc tgcctttact tagccagaaa ccctattaca
    66781 gcaagctgac ttacggctac gctcgtggac atgaagccta cgcttatgtc gaaaatattc
    66841 gtaagtatca gattagcctg gtgggttatc tgcaagagaa agagaagcag gctacagaag
    66901 cggcgatgca actggcgcag gattatccgg cggtatcgcc tacggagttg ggcaaagaga
    66961 aatttccttt tctctcgttt ctttcccagt cgtcatcaaa ctatttgacc cattctccct
    67021 ctctgctgtt ttccaggaaa gggagtgaag agaaacaaaa ttaatccgtc gaggattgcg
    67081 cttttttctg cgctttaatt tcctggcggc gcatgcgaaa gaagtcactg agcaacgccg
    67141 cgcactcatc cgccagtatt ccttccgtaa tttccactcg gtgattcata cccggatgat
    67201 gcagcacatc cattaaagat cccgcagcgc cagttttcgc gtcacgcgca ccaaagacca
    67261 cgcgaccaat gcgactgtgg atcatcgctc cggcacacat tacacatggt tcaagcgtga
    67321 catacaacgt ggcgtcgatc agacgataat tttgcatcac cagaccaccc tgccgcaggg
    67381 ccatgatttc tgcatgtgcg gtgggatcat ggcgaccaat cgggcggttc cagccttcgc
    67441 cgattacccg attgttatgc actaataccg cgccgaccgg cacttcccgc tcatcccagg
    67501 cacgtttcgc cagcgtcagc gcgtgacgca tccagtattc gtggctaaat tcgacttcag
    67561 acaaaaagaa aactccggtt ataaaagcgc ggcgcattat acacggacgc tatgctttac
    67621 tctattccag ttgctggagt tcaccgcgcg gggttactcg ccaacgatgc tgacagaaat
    67681 aaagcagcgg attgtcctga ttactgtcgc tatagccact gtacagccgc agcggagtgc
    67741 cgattttgcg ctccagttgt gcgacctttt catgtcccag acaacgcatc gtcaataccc
    67801 aaccaccata gccacgctga atttggctgg cgataagatt aacccgcggc agccagggcg
    67861 tatcgaaata aaccgcttca accagcggct gcggagagcc ggtaatcaac cagatatcag
    67921 catcggaact taacaggtag gtggttaatc gctcctgaac cagcggaaag gcggtaacat
    67981 tgtcgcgaaa ccagcgcacg aaatcggcct gcaacgtctg taaacgtgct tcgctgtgac
    68041 caaaagtgca cccccacaga agcagactca tcggccagcg tgccgcacga ccttttatca
    68101 ataacgcaat ggctataatc ggtaacaacg gcaggacaag taacgcattc agcggttggc
    68161 gacgcagtaa atagcgcaga aaactgccga acatatcctg ctgatgcaat gttccatcta
    68221 agtcaaaaaa caccacacga cgctcgtgag ttgccaaacc atactcctct ggactgaaac
    68281 atcctgatta attttcgcta ctacatagcc taacagatag atcatcactt ttccggcaac
    68341 aatcgaccgc atcatggcta actggaattt ttaattcatg gcaattagcg gcaatggaat
    68401 ataaaattca ctcgcgtgtc tctcatattg cctgttgtcg ccactatttc atcgcgagga
    68461 aagatatgaa cggcttactt cgtatccgtc agcgttacca ggggcttgcc cagagtgata
    68521 aaaaactggc ggattatctg ctgctacaac ctgatacggc gcgccattta agctctcagc
    68581 aactggccaa cgaagccgga gtcagtcagt ccagcgtcgt gaagttcgcg caaaaactcg
    68641 gctataaagg ttttccggcg cttaagttgg cgttgagtga agcgctggca agccagccgg
    68701 aatcgccctc cgtgcccatt cataaccaaa tccgcggtga tgatccgtta cggctggtcg
    68761 gcgaaaaact gattaaagaa aatactgccg ctatgtacgc aacgctaaac gttaatagtg
    68821 aagagaaact gcatgaatgc gtaacaatgt tgcgctctgc gcggcggata attctgaccg
    68881 gtattggcgc ttcgggtctg gtggcgcaaa actttgcctg gaagctgatg aagattggct
    68941 tcaatgctgc cgcagtgcgc gatatgcatg cgctactcgc aacagtacag gcgtcgtccc
    69001 ctgacgatct gttattagcc atttcctaca ccggtgtacg acgcgagtta aacctggcgg
    69061 cagatgagat gctgcgagtg ggcggaaaag tgctggcgat taccggcttt actccgaatg
    69121 ccctgcaaca gcgtgcttct cattgcctgt ataccattgc cgaagaacaa gcgacaaaca
    69181 gtgcttcaat ctctgcttgt cacgctcagg gaatgttaac ggatttgctg ttcattgcgc
    69241 tgattcagca ggatctggaa ctggcaccag aacgtattcg tcatagtgaa gcgctggtga
    69301 aaaaactggt ctgagtaaag aatgcgcgta taatgcccgc ccggtttgtg ttgttttgag
    69361 agtttcctta tggcgttgtt aatcactaaa aaatgcatca attgtgatat gtgtgaaccc
    69421 gaatgcccga atgaggcgat ttcaatggga gatcatatct acgagattaa cagcgataag
    69481 tgtaccgaat gcgtagggca ctacgagaca ccaacctgcc agaaggtgtg cccgatcccc
    69541 aatactattg tgaaagatcc ggcgcatgtc gagacagaag aacagttgtg ggataaattt
    69601 gtgctgatgc accacgcgga taaaatttaa tattctactc tggaagtaga gtattaatta
    69661 tattactggg aagccttaac gccattatat ttatttaatt gatgacatta gcataatcat
    69721 tcactaagtt aatttatata gtatctgcca agacacttat ttatagttat taaaggcgcg
    69781 tccgattggc tcaccggacg caccttaagt acgtttcctt gtgttataag aacagaagga
    69841 tcagctgtaa aacagcaatg atgattttga tgacccgttt aatcaggtat cggcaatcag
    69901 tcattcgttt ttccttaaac aaggaatgca gctgttcaga ttagccctta catctcccca
    69961 aaactgaacg tgcgagttat tgagggtgca tgctgcactc cacaccagag ctttgacgac
    70021 accactcgtt tcaatggggg aattctgtgg catggtgtaa agcacagcaa aatcttcaat
    70081 aacgaagcca attttaatgt acttacgaat tggcggtcac gttaatcttt ccatcaatat
    70141 tgctttcttc gtaaaggctc gagtttttat gctaaagatt gcaagttgct tgtaaaagat
    70201 aagtacactg atccataatc gctgttgttg agggtgcatg ctgcacaaaa ttaaagttaa
    70261 aaagtaaaac ccccgttcct taccagttcg ggggttttac tttttaaaga gaacggtatt
    70321 attttaactt tcaataatta ccgtggcaca agcatagtgg cgttcatctg ccagcgttac
    70381 atgcatattt acaacgccga gcttttccgc cagttttaat gcctcacccc atagccgtag
    70441 ccgtggtttg ccgagctcat cattgaatac ttcaaattga ttaaacgcca gaccattgcg
    70501 gatcccggtg ccaaacgctt ttgctgcggc ttctttcaca gcaaaacgct tcgccagaaa
    70561 acgcaccggc tggtggtgcg ttttccagat tgcccattcg ttatcgctta atacgcggcg
    70621 tgccaggcgc tcaccggatc gggcgatcac tgcttctatg cgagcgatct ctacgatatc
    70681 cgtgcctaaa cctaatattg ccattagcca cgcgcttcca gcatcagacg cttcatttct
    70741 gccaccgcat ctttcagtcc ggtcatcact gcacgaccaa taatggcatg accgatattc
    70801 agttcatgca tctcagggat ggcggcaata gctttcacgt tgtgataggt cagaccgtga
    70861 ccagcgttaa ctttcagacc gagactagcg gcaaaggtcg cggctttggc gatacgcgcc
    70921 agctcttgcg cctgttcggc gtcagttttg gcatcagcat agcaaccggt gtggatctcg
    70981 ataaacggtg cgccaacctc tgccgcagct ttgatctgct cttcatcggc gtcgataaag
    71041 agagaaacct ggatcccggc atctgccaga cgtttgcagg catcgcgcat tttgtcacgc
    71101 tgccctgcga cgtccaggcc gccttcggtt gttacttcct gacgcttttc cggtaccaga
    71161 cagcaaaaat gtggcttcgt ctcaacggcg atcgccagca tctcttcggt caccgccatc
    71221 tccagattca tgcgggtatc cagtgtctga cgcaggatgc gcacatcacg gtcagtaatg
    71281 tggcggcgat cttcacgtaa atgcacggta atgccgtccg ctcccgcctg ctcagcaata
    71341 aacgccgcct gcaccggatc cgggtaagca gtaccgcgtg cgttacgcag cgttgcaata
    71401 tggtcaatgt tgacgcctaa cagtaattca gccatgacaa tcctcatcat tcataatgtg
    71461 ttttcaccgt tcgcttaggc ataaactgcc ggaacagttc cctgctcttt aatggtttac
    71521 cgccaagata cggcttaagc gccatgcggg taaagcgttt cgcggcgcgt agtgtgtctg
    71581 cgtcaggaaa ttcccgcgcg tttaacgctt ttaactgcct tccggtgaac gttttattgt
    71641 cgataacgac gcttgcgata aacccttttt cttcgcgata acgatacgtc atggtgtcat
    71701 ctaccggctc gccgctaccc gcacaatggg taaaattgac gccatagccc agatgcccga
    71761 gcagtgccag ttcaaagcgg cgcagcgcgg gttctggcgt accagtggca cctgcaagag
    71821 actgaatgca gtgcaagtaa tcgaaaaaga gttcagagaa gcgcgtctcg tattccagta
    71881 cgcgggagag aagttcgttg atgtacagac cgctgtaaag cgtgataccg cttaatggca
    71941 gcgccagcga gacagcttca gcactgcgca gcgttttgac ttcgccacgc ccgccgaaac
    72001 gtagcaagag aggggtgaaa ggctgtaatg cacctttcag agtagagcgt ttagagcgtg
    72061 cgcctttggc aaccagacgc acgcgacccg attcctccgt gaagacgtcc agcatcaggc
    72121 tggtttcgct ccacgggcga ctatgcagga caaatgcgcg ctgccagcct tccatcggag
    72181 tgactcttaa agatcgtcaa cgtaaccgag actgcgcagt gcgcgttcgt cgtcggccca
    72241 accggatttc acttttaccc acagttcaag gtggacaggc gcttcgaaca tttcctgcat
    72301 gtctttacgc gcttcaatcc cgatggtttt gatcttggcc cctttgttgc caataaccat
    72361 cttcttctgc ccttcacgct caacgagaat caaaccattg atgtcataac caccgcgttc
    72421 gttagagacg aaacgttcga tctccacggt cacggagtac ggcagttcag cgccgaggaa
    72481 acgcatcagt ttttcgcgga tgatttcaga cgccataaaa cgctgtgagc gatcggtgat
    72541 gtaatcttcc gggaagtgat gggtcgcttc agggaggtgc ttacgcacga ttgctgcgat
    72601 agtgtcgaca ttcagcccgg tttcagcaga gatcggcacg atatcgagga agttcatctg
    72661 acttgccagg aactgtaagt gcggcagcag atcggctttt tcctgcacgt tatccacttt
    72721 gttcaccgcg aggatcaccg gcgctttgcc atcgcgcagt ttgttgagca ccatttcgtc
    72781 gtccggcgtc cagcgggtgc cttcaacgac aaaaatcacc agctcaacgt cgccaataga
    72841 gctgctcgcc gctttgttca tcaggcggtt aatagcgcgt ttttcttcca tatgcaggcc
    72901 aggggtatca acgtagatcg cctgatacgc gccttcagta tggatcccca caatgcggtg
    72961 acgagttgtt tgcgctttgc gggaggtgat ggagatcttc tgccccagca gtttgttcaa
    73021 caatgtggat ttgccaacgt tcggacgtcc gacgatggca ataaatccgc agtaactttt
    73081 atcgatgctc attccagctc cagttttttc aacgcctgtt cggcggcagc ctgctcagcc
    73141 ttacgacggc ttgaacctgt gccaaccacc ggttcactca ggccgctgac ctggcagtgg
    73201 atagtaaatt cctgatcgtg cgcttcgcca cgtacctgga ctaccagata agtcggcagc
    73261 ggcagatggc gaccctgcaa atattcttgc aagcgcgttt tcggatcttt ttgtttatcg
    73321 cctgggctaa tttcgtccaa acgagtttga taccagttga ggattaattt ctcgacggtt
    73381 tgaatatcac tgtcgaggaa tacgccacca attaatgctt cgacggtgtc ggcgagaatt
    73441 gactcacgac gaaatccacc gcttttaagt tcacctggcc ctaaacgtaa gcactcgcct
    73501 aactcaaatt cgcgcgccag ttccgccagc gtattgccac ggaccagcgt ggcgcgcatc
    73561 cggctcatat cgccttcatc cacacgaggg aaacggtgat aaagcgcatt ggcgataacg
    73621 tagctcagaa tagagtcgcc taaaaattct aaacgctcgt tatgtttact gctggcacta
    73681 cgatgagtta atgcctgctg caacagttcc tgatgattaa aagtgtagcc cagcttccgt
    73741 tgaagccgat taattacgat ggggttcatg cgataccaat aaataaatgc gtcaacaatt
    73801 cagcacacga aacagacctg atatacatgg ctctgctaac tgcttcgctg cagtttcagt
    73861 ttaccggtat atggggacca acgctgtttc gtgtgccgtg gcaacctgga ggtgccaacc
    73921 ttaaacttcg ggggaatatt ctatacacaa cgacggggga tgtcgttagc cacgggagat
    73981 ttatctcata aataattcac gttgtcgcca taacggcgac aacgtgaacg aagatgagct
    74041 attaatggat gccgccaatg cgacttaagc gcacaccagt cggccattcg ccttcttgct
    74101 tatcgaagct catccagata gccgttgccc gaccgaccag attcgcttca ggcacaaacc
    74161 cccaataacg gctgtccgcg ctgttgtcgc ggttgtcgcc catcatgaag tattgtcccg
    74221 gaggaacaat ccaggttgcc agttgttgcc ctggctgctg gtaatacatc cccacctgat
    74281 cctgcgcaat cggcactgtc agaattcggt gcgtcacatc acccagtgtc tctttacgct
    74341 cggaaagacg aattccattt tctttggttt cgtttttcgg cacttcaaag aatccgctgg
    74401 tcgcttcccc accattacgg cgtgagaagg tctgaacgaa atcgctcggt tccacgtttg
    74461 agtaggtgac cggcagcgcg ttttcacacg cctggccgga actgcatccc ggttgaatcg
    74521 tcagctcttt cgagaccgga tcgtaagtga ctttatcgcc cggtaaaccc accgcgcgct
    74581 tgatgtaatc aagctttgga tcttccggat atttaaagac cacgatatct ccgcgtttcg
    74641 gatgaccggt ttcgatcagc gttttctggt agataggatc tttaatgcca taagcaaact
    74701 tttctaccag aataaaatca ccgattaaca gagtcggcat catcgaacct gacgggatct
    74761 ggaacggttc ataaataaac gaacgcacaa tcaatacgat agccagcacc ggaaaaacag
    74821 aagcaccggt ttccagccag ccaggcttcg gcgcaacctt tttcagggtt gctttatcca
    74881 gtgagtcacc ggcagccgcc tgcgccgctg cctgacgttc ccgccgttta ggtgcgaaaa
    74941 agaatttatc cacgcaccat aaaatgcccg tcaccagtgt ggcaatcacc agaatcaggg
    75001 caaacatatt cgccatgcca actcctaagg gttatttgtt gtctttgccg acgtgcagaa
    75061 tggcgaggaa cgcttcctgc ggcagctcga cgttaccgat ctgcttcatg cgtttcttac
    75121 cttctttctg cttctgcagc agctttttct tacggctgat atcgccgcca taacatttag
    75181 ccagtacgtt tttacgcagc tgtttcacgg tggatcgcgc aataatgtgc gtaccaatcg
    75241 ctgcctgaat ggcgatatca aactgctggc gtgggatcag atctttcatc ttctccacca
    75301 actcgcgacc gcggttttgc gaattatcac ggtgggtgat cagcgccaac gcatcaacac
    75361 gttcaccgtt gattaatacg tctacacgta ccatgtcgga cgcctggaag cgtttgaagt
    75421 tgtaatccag agacgcataa ccacgcgagg tagatttcag gcgatcgaag aagtcgagca
    75481 ccacttccgc catcgggatc tcgtacgtca gcgccacctg attaccgtgg taaaccatat
    75541 tggtctgcac gccgcgtttt tctacgcaca gcgtaataac gttgccgaga tatgcctgcg
    75601 gcagcagcat gtgacattcg gcaatcggct cgcgcagttc gtagatgtta tttaccgctg
    75661 gcagcttgga tggactgtcg acgtaaataa cttctcttga cgtggtttca acttcataca
    75721 ctacggtcgg cgcagtggtg atcagatcca gatcgtattc acgttccaga cgttcctgga
    75781 tgatctccat gtgcagcagg ccgaggaagc cgcagcggaa accaaagccc agcgcgctgg
    75841 agctttccgg ctcatagaac agtgaagcat cgttcaggct gagtttaccc agcgcgtcac
    75901 ggaaggcttc atagtcgtcg gaacttaccg ggaacagacc ggcgtatacc tgcggtttga
    75961 ctttcttaaa gccaggcagc gccttttctg ccggattacg cgccagcgtt aaggtatcgc
    76021 cgactggagc gccgtggata tctttaatcg cacataccag ccagcctact tcgccacatt
    76081 tcagttcagt gcggtcaacc tgtttcggcg tgaagatgcc cagacggtcg gcgttatagg
    76141 tctgcccggt actcatgact ttcactttgt cgcccttacg cagggtgccg tttttaatac
    76201 ggataagtga aacaacgccc aggtagttgt cgaaccatga gtcgataatt agtgcctgca
    76261 acgggccttc cggatcgcct tccggcggcg gaatgtcgcg caccagacgt tcgagaacgt
    76321 cctgcacgcc aacgccggtt ttcgctgaac agcgcaccgc gtcggtggcg tcgatgccga
    76381 cgatatcttc aatttcttcc gccacgcgtt caggatcggc tgccggcagg tcaatcttgt
    76441 tcagtaccgg caccacttcg agatccattt ccatggcggt gtagcagttt gccagggttt
    76501 gcgcttctac gccctgcccg gcgtcgacca ccagcaatgc accttcacag gcagccagcg
    76561 aacgggaaac ttcataggag aagtcaacgt ggcccggggt gtcgataaag ttcagctgat
    76621 aggtttcgcc gtcagacgct ttgtagtcca gcgtcacgct ttgcgctttg atggttatgc
    76681 cacgctcacg ctcaagatcc atggaatcga gaacctgcgc ctccatttca cggtcagaca
    76741 ggccaccgca gatctggata atacggtcag acagcgtcga tttaccgtgg tcaatgtgag
    76801 ctatgatcga aaagttacgt atattcttca taaagtatga ttattgtgcc ttaatgcccg
    76861 gttaaccagg cttttagaag tcgctgttct gagcttaacg tctgtattaa tagaaacgcc
    76921 gcattctaca ctacaacatt gaggcgagga aatgttcata ccgtatggat tgtggtatct
    76981 ggaaacgtcc tcgcatttgt tatgcaaaat gcaacaaagc cagtgaaatc actggctcgc
    77041 gtcttccgaa gatgtttcaa atcgcacaag gccaggcggc aatgccacgc ttaagatgat
    77101 cggttgccat tctgcccggg cagcaaactt acgcgagtag ccgcgcgcaa tcaggaaccc
    77161 gccaataccg ccgaggaccg caccacataa tgctgcgacg tcagaagcaa agagtagctg
    77221 aaatagcgaa gcgatgagga ataatcccac cagcggcgac atataaacca gtaatgcgga
    77281 gctaagcagg ctgccttcgg cgatccccaa ttccactttt tgccccggca ctaacggctc
    77341 atcacagggt acgacaatgg tatgcgtggt ttgcgggcca agtttattta acacgcggct
    77401 accgcaaccg gcgcgtgaag cgcagctgct gcatgaagct ttaacatcac aactgaccag
    77461 cgcctgcccg ttttgccagg agacgacggt agcccactct ttgatcattg cgctgccccg
    77521 aacttaatat tctcggcaat gcgtttcgcc gtttgcggcg gcagttcacc gacaatggtg
    77581 atttcggcgt tatcacgtac gcttgtactg acggttctgc gtccggtgcg caacatctga
    77641 tcggtgctcg atggcgtagc gcggttaacg tttaccgaga agctgaataa tccgtcggaa
    77701 tagagacgtg attcgatagg catgttgtcc atcgtcggta gcggacgtcg actactggaa
    77761 acttcgctaa aaccctgtgg caaccaggtt ggcgtccagc tgaatttagc tttttcacct
    77821 acaggaacag aaagcaacgg cggcaaattt gccttcgcca gcgtctgcat actgctgctg
    77881 atatcctgat tgacgttaaa agcaatcacg cgaaattgtt ccagcgtttc accatcgcga
    77941 tcaaggagat caacccgcat cggtaatttc gattcggtgt ccatccacac gatgtagctg
    78001 tagcgtgtac catctcgggc aaccacgcga atgacttcgc aaagacgatc agcaatacgc
    78061 gtgcgcccga cggagataaa gtcgtagtaa ggagaaaggc gtttgaaatc ggtatagata
    78121 agcgatggca gagaatcaac aatgtaatcg ccattaagcg tgaacggttc aagtcccggt
    78181 tcaaaatagc tgatttcatt gccgcgctgt accacttccc ggcgcgggcc atccatttgc
    78241 aacaattgtg caagagggcg gttatcgagg cgtgcatgtc gataacgcag agactcaaca
    78301 ccctgtttat tgatgctgat gaatgacagc tcgtaattca gtgactgact ggccaggttc
    78361 atctgctgta ataacgcccc ggacgcggga gtggccgagg cgttagcaga gaataacagg
    78421 ctacctgtca ctaatgacat ggcaaaccaa agttgcttca ttactgcgat tgcgttccta
    78481 aagtttgaat tcctggcacc tgtacagcgg cttgctgggt ttgcgcctgc tcaaactgaa
    78541 gctgttcaga gtggagtcgg cgttgcagtt cgtaatcctg caacattgca ttaatgcgac
    78601 gacgctgctc ctgtacctgc tgctgttgac cattgtttgc ggtcgcttca gaaggtactc
    78661 ccaggcttac cgggctggct ttacccatca tcggcagtgt attaaatacc ggcgtttcgg
    78721 gctgctggga cgtttcagat tgtccattat agtgctggac gccaacgata actgcaagcg
    78781 atacgcatgc tgctacgccc atttgggtaa gctgtgccgc ccacggacgt actttctgcc
    78841 agaatggcat tttctgccat tgatgcggcg caggctgggc ttccgggatc aatgtcgccg
    78901 gttgacgtac tggctcttct tcaatggcgg ccatcacgcg tgaagagata tcgaaatgga
    78961 gcacctcggg agtatcaccc cgcattgagt cacggattaa gtgatagctt tcccaggttt
    79021 tctgcatttc tgggttatga gccagttcgt taagcagctc actatccagc gtttcgccat
    79081 ccattaaagc ggaaagttgt tctttctgca tgcctaatac ccttatccag tatcccgcta
    79141 tcgtcaacgc ctgataagcg gttgaacttt gttatcaata gcttccctcg ctcggaagat
    79201 acgtgaacgc accgtaccta ccggacaatc catgatagcg gctatctctt catagctcag
    79261 gccatccagc tcccgcaagg ttattgccat gcgcaaatct tccgggaggg actcaatagt
    79321 tcggaaaact atctgtctca gttcttctga caacattaag ttctcagggt tcgaaatttc
    79381 tttcaacgcg ccgccacttt cgaagttttc agcttcaatg gcatccacat cactggaagg
    79441 tggacgacgc ccctgagcaa ccaggtaatt tttcgctgta tttacagcaa tccgatacag
    79501 ccatgtataa aaagcgctat ctccccggaa cgaatccagc gcacgatagg ctttaataaa
    79561 agcttcttgt accacatcgg gaacatcacc cgacggcaca tagcgggaaa ccagactcgc
    79621 cactttatgc tgatagcgca ctaccagtag gttaaaggct ttctgatctc ccttctggac
    79681 ccgttcaacc aggacctggt ccgttaactg ctcgctcatc cgaggtaaag tctccccaaa
    79741 ccaaatttcc acgcgctatc gaaacgccac tccattagct gcaatttgag caagcaaagg
    79801 gttagagtgt ctcgtttttg taaagttccg taacgcatct gtttttgttt gtcatgctgt
    79861 agacggatca ttatctatca ttataagtct acagaatctg aacatcgcat tatctgtgta
    79921 gaaatgccca tttaactgcc tgaagagtaa cccaacggcc tttttatttc accacctaat
    79981 cctccaccag ccagtaactt ctctttttct cgccgccctg cgtcagcgtg tttagccact
    80041 gtaacaaata ttaaaatagc aggtgtttat tcgcacaaca tgatgctatg ctgaccaaac
    80101 ggtgtttagt aaattaaaca aagaaaatga atactctccc agaacattca tgtgacgtgt
    80161 tgattatcgg tagcggcgca gccggacttt cactggcgct acgcctggct gaccagcatc
    80221 aggtcatcgt tctaagtaaa ggcccggtaa cggaaggttc aacattttat gcccagggcg
    80281 gtattgccgc cgtgtttgat gaaactgaca gcattgactc gcatgtggaa gacacattga
    80341 ttgccggggc tggtatttgc gatcgccatg cagttgaatt tgtcgccagc aatgcacgat
    80401 cctgtgtgca atggttaatt gaccaagggg ttttgtttga tacccacgtt caaccgaatg
    80461 gcgaagaaag ctaccatctg acccgtgaag gtggacatag tcaccgtcgt attcttcatg
    80521 ccgccgacgc caccggtaga gaagtacaat ccacgctggt gagcaaggcg cagaaccatc
    80581 cgaatattcg tgtgctggag cgcagcaacg cagttgatct gattgtttct gacaaaattg
    80641 gcctcccggg cacgcgacgg gttgttggcg cgtgggtatg gaaccgaaat aaagaaacgg
    80701 tggaaacctg ccacgcaaaa gcagtggtac tggcaaccgg cggtgcgtcg aaggtttatc
    80761 agtacaccac caatccggat atttcttctg gcgatggcat tgctatggcg tggcgcgcag
    80821 gctgtcgggt tgccaatctc gaattgaatc agttccaccc taccgcactg tatcacccac
    80881 aggcacgcaa tttcctgtta acggaagcac tgcgcggcga aggcgcttat ctcaagcgcc
    80941 cggatggcac gcgttttatg cccgattttg atgagcgcgg cgaactggcc ccgcgcgata
    81001 ttgtcgcccg cgccattgac catgaaatga aacgcctcgg cgcagattgt atgttcctcg
    81061 acatcagcca taagcccgcc gattttattc gccagcattt cccgatgatt tatgaaaaat
    81121 tgctcgggct ggggattgat ctcacacaag aaccggtacc gattgtgcct gctgcacatt
    81181 atacctgcgg tggtgtaatg gttgatgatc atgggcgtac ggacgtcgag ggcttgtatg
    81241 ccattggcga ggtgagttat accggcttac acggcgctaa ccgcatggcc tcgaattcat
    81301 tgctggagtg tctggtctat ggctggtcgg cggcagaaga tatcaccaga cgtatgcctg
    81361 atgcccacgg cgtcagtacg ttaccgccgt gggatgaaag ccgcgttgag aaccctgacg
    81421 aacgggtagt aattcagcat aactggcacg agctacggct gtttatgtgg gattacgttg
    81481 gcattgtgcg cacaacgaag cgcctggaac gcgccctgcg gcggataacc atgctccaac
    81541 aagaaataga cgaatattac gcccatttcc gcgtctcaaa taatttgctg gagctgcgta
    81601 atctggtaca ggttgccgag ttgattgttc gctgcgcgat gatgcgcaaa gaaagccggg
    81661 ggctgcattt tacgctggat tacccggaac tgctcacgca ttccggtcca tcgatccttt
    81721 cccccggcaa tcattacata aacagataaa aagcctgggt cagcgccgta tacgcttcgg
    81781 aatagttctg gtctggccca cgaatgacta agcgatcgct aaagcattct cccgcctgcg
    81841 gggagaatgc cagcagcacc cgatgcggca gtcgcgcttc gttttccgcc acatccgtcc
    81901 gcaaacgtaa atgccagccc atgcttaatg ccagttcagt aaaaccatta ccaatctgct
    81961 ctggcagcac cacgcagaaa aatccctctt cggtaatgca ctccgccgca caggtcagca
    82021 gcgatgggtg atcaagcgta gtggtatagc gagcctgttc ccgttgaggt gtcgcgcact
    82081 ctactccctg ctgatagtaa ggtgggttac tgatgattaa atcgaagcgt actgtctgct
    82141 gtgtgatcca ctgctgaata tccgccgtat ggacgttaat ccgctctgcc cacggggact
    82201 ggttgatatt ttcctgcgcc tgcgcggcag cttcactttc cagctcaacg gcatcaatta
    82261 tcacgctgtc actggttcgc tgcgccagca tcagtgccag caacccgcta cccgcgccga
    82321 tatcaaggca acgtttcacc ccagccaccg gtgcccatgc gcccagcaaa atgccatccg
    82381 ttcccacttt catcgcacag cgatcgtgag caacaaaaaa ctgtttaaaa gtaaatccat
    82441 tacgacgaag cacggatgta gactgtgaca tgaaaataaa accttgcagg aaaaacggcg
    82501 atagcaccgg gtgagaacaa tacccgagaa gcgatatcca tacaaacaga tgaagattgc
    82561 agccgtaacg tctataatca gcgccccaca cagaggtaga acatgactgt aacgactttt
    82621 tccgaacttg aactcgacga aagcctgctg gaagccctcc aggataaagg tttcactcgc
    82681 ccgaccgcca ttcaggctgc cgccattccg cctgcgctcg atggccgtga tgtactcggt
    82741 tctgcgccga caggcaccgg taaaacggcg gcgtatctgc tgccagcgtt gcagcacctg
    82801 ctcgatttcc cgcgtaagaa atccggtccg ccgcgtattt tgatcctcac cccaactcgc
    82861 gagctggcga tgcaggtggc cgatcatgcc cgcgaactgg cgaaacatac gcatctggat
    82921 atcgccacca tcaccggcgg cgtagcctat atgaaccacg cggaagtgtt cagcgaaaat
    82981 caggacatcg tggtcgccac gaccggacgt ctgctgcaat acataaaaga agagaacttc
    83041 gattgccgcg cggttgaaac gctgatcctc gacgaagcag accgtatgct ggatatgggc
    83101 ttcgctcagg atatcgaaca tattgctggc gaaacgcgct ggcgtaaaca gaccctgctc
    83161 ttttcggcaa cgctggaagg cgatgcgatt caggactttg ccgagcgtct gctggaagat
    83221 ccggtggagg tttctgccaa tccgtccacc cgtgagcgca aaaaaattca tcagtggtat
    83281 taccgcgccg atgacctgga acataaaacc gcattgctgg tgcatctgtt aaaacagccg
    83341 gaagcgaccc gctcaattgt gtttgtgcgt aagcgtgaac gtgtgcatga gctggcaaac
    83401 tggctgcgcg aagcgggcat caacaactgc tatctcgaag gtgagatggt acaaggcaag
    83461 cgtaacgaag cgatcaagcg tttgaccgaa ggtcgcgtaa acgtactggt tgcaaccgat
    83521 gttgccgcgc gcggtatcga cattcctgac gtcagccacg tctttaactt cgatatgccg
    83581 cgcagtggcg atacttattt gcaccgtatc ggacgtaccg cgcgcgccgg tcgtaaaggc
    83641 accgcaattt cgctggtgga agcccatgac catttgctgc tgggcaaggt tggccgttac
    83701 attgaagagc cgattaaagc tcgcgttatt gatgagttac gcccgaaaac gcgtgcgcca
    83761 agcgagaagc agaccggcaa gccatcgaag aaagtactgg caaaacgcgc cgagaagaaa
    83821 aaagctaaag agaaagagaa accgcgtgtg aaaaaacgcc atcgcgacac caaaaatatt
    83881 ggtaagcgcc gtaaaccaag cggaacgggc gtgccaccgc aaacgacaga agagtaatct
    83941 caatgccggg tttaagcctg gtattaaaag tgctggcaaa cgcaaaactg cctgatgcgc
    84001 tacgcttatc aggcctacgt ggctcatgca atatattgaa ttttcacgat cttgtaggcc
    84061 ggataaggcg ttcacgccgc atccggcatg aataaagcgc actttgtcga caagttaaat
    84121 gccgggttta atcccgacat tatttttatc cagccacaaa actctcttca acacactgaa
    84181 taaaagtgtg catcgccggg ctaaccgctt ttccagcatg gtgtgcgcac atggccgtaa
    84241 tggtctgcga ctgttcgcca aaaggcaatt caattaattc tccgctctca agctcttttt
    84301 ccaccgcaaa gcggggcaag taactgacac cgatattcgc cgcgacacaa cgtttgatac
    84361 tttcaatgct taacagctca atggtgtttt ccaccgtgat ccgccgctga cgcagcgtgc
    84421 tctcaaatat ctgccggaag acacattgcg gttcgttgat aataaagcta caggcgttat
    84481 gtcttcccgg ctcagtaaaa tcgacatctg caatttgcgg tgaagccacc agcaccagcg
    84541 attgttcacc caactctcgt cggttcaggg catcatcatt ccctacgcga taaaagacgc
    84601 cgacatcggc ctcatcattc agtagcgcat cacggatcac gtaacagttc agcgactgca
    84661 acgataaacg cacttttggt gcgcgttgcc gaaaacgctg caacacctgc ggcattcggt
    84721 aagagagcaa cgtttcgccc gaaacaacgc gtagttcccc gtccggatcc gactcttttt
    84781 tcgcagcctc acgaagcgta tccatcactc gggtaagttc atagatgtgc ggcagcaact
    84841 tttttccttc gcgggtaagg cacattcgtc gaccaatttt ctcaaacaat tgtaccgaga
    84901 actcctgctc aagctgctga atatgaaaag tcaccgtcga ttgtgtacag cacaattttt
    84961 gcgaagctcg caaaaaggaa ccctcttcca ccacggtttt aagtgtaata aaacggcgca
    85021 gatccataac cccaaaccta tcgaaaatat cgaatttaga atgtaaaaac attcattttt
    85081 ttaaatgttc cgtgtcgggt actgtctacc aaaacagagg agataacaag tgacaccgac
    85141 ccttttaagt gctttttgga cttacaccct gattaccgcc atgacgccag gaccgaacaa
    85201 tattctcgcc cttagctctg ctacgtcgca tggatttcgt caaagtaccc gcgtgctggc
    85261 agggatgagt ctgggatttt tgattgtgat gttactgtgt gcgggcattt cattttcact
    85321 ggcagtgatt gacccggcag cggtacacct tttgagttgg gcgggggcgg catatattgt
    85381 ctggctggcg tggaaaatcg ccaccagccc aacaaaggaa gacggacttc aggcaaaacc
    85441 aatcagcttt tgggccagct ttgctttgca gtttgtgaac gtcaaaatca ttttgtacgg
    85501 tgttacggca ctgtcgacgt ttgttctgcc gcaaacacag gcgctaagct gggtagttgg
    85561 cgtcagcgtt ttgctggcga tgattgggac gtttggtaat gtgtgctggg cgctggcggg
    85621 gcatctgttt cagcgattgt ttcgccagta tggtcgccag ttaaatatcg tgctcgcgct
    85681 gctgctgatc tattgcgcgg tacgcatttt ctattaatta aaaaagcgga agaggtcgcc
    85741 ctcttccgct tagtaacttg ctacttaagc cttacaggct ttcagtaaag gtacgagcga
    85801 taacgtcgcg ctgctgttcc ggagtcagag agttaaagcg aactgcataa cctgatacac
    85861 ggatggtcag ctgcggatat ttttccggat gcttaactgc atcttccaga gtttcacgac
    85921 gcagaacgtt aacgttcagg tgttgaccac cttcaacgcg aacttctggt ttcacttcta
    85981 ctggaacttc acggtattca atgtcaccca gtttgcttac tgcaaccact tcatcttctg
    86041 cataacctgc ttttgcaacg atgcaacgcg cttcgccttt ttcgctgtcc agcagccaga
    86101 aagagttcag cagatcgtcg ttagcggctt tagtaatctg gatacctgta atcatgtgat
    86161 gcctccccgg caaaattatt tgatttattc aacctgtcgc ggccaattgg taaaaccatt
    86221 gttgcttgag tgtatatata ctcctcaaca acccttgatt ccttgattta aatcaataaa
    86281 aaccacacat cgattgtggt cgcaaatgga ttttattgtt ttacatcaac ttatgcgggt
    86341 gtgaaatttt accaatttac atttttttgc actcgtttaa gtctaaaaaa tgagcatgat
    86401 tttgttctgt agaaataagc agttaagcta ggcggattga agattcgcag gagagcgaga
    86461 tggctaacga attaacctgg catgacgtgc tggctgaaga gaagcagcaa ccctattttc
    86521 ttaataccct tcagaccgtc gccagcgagc ggcagtccgg cgtcactatc tatccaccac
    86581 aaaaagatgt ctttaacgcg ttccgcttta ccgagttggg tgacgttaaa gtggtgattc
    86641 tcggccagga tccttatcac ggaccgggac aggcgcatgg gctggcattt tccgttcgcc
    86701 ccggaatcgc cactcctccg tcactgctga atatgtataa agagctggaa aatactattc
    86761 cgggcttcac ccgccctaat catggctatc tcgaaagctg ggcgcgtcag ggcgttctgc
    86821 tgctcaatac tgtgttgacg gttcgcgcag gtcaggcgca ttcccacgcc agcctcggtt
    86881 gggagacgtt tactgataaa gtcatcagcc tgattaacca gcaccgcgaa ggcgtggtgt
    86941 ttttgttgtg gggatcacat gcgcaaaaga aaggggcgat tatagataag caacgccatc
    87001 atgtactgaa agcaccgcat ccgtcgccgc tttcggcgca tcgtggattc tttggctgca
    87061 accattttgt gctggcaaat cagtggctgg aacaacgtgg cgagacgccg attgactgga
    87121 tgccagtatt accggcagag agtgagtaaa tttgcgggga aatgccggat ggcagagttg
    87181 ccacccggct gatttatcag gctttattct gacgccacca ttcaccaagc aaaacgccgg
    87241 ttgcgacaga gatattcagc ccggcaacgt tgcccgtacc gtcaatcttc acgcgcagat
    87301 cgttcggatc gcgtgcggca tccggtaacc cttcatattc ctgacccagc accagtacca
    87361 ttttcgctgg cagactggtt ttgaacagcg gtttaccctg ctcgctggaa gtggtcacta
    87421 cggtgtaacc tgcctgacgg aaatcatcca gcacgttaac aatgttgtcg ccagtaatcg
    87481 gctgaacgtg ctctgcgccg ccttctgcgg tacggatagc cgcccccgac tccagcagtg
    87541 ccgcatcctg caccacaacg cctttcacgc cgaagtgcgc gcagctgcgc atcatgccac
    87601 ccaggttatg cgggttagat tcgttttcca gcgccagtac acaatcctgc gcgcctgcct
    87661 ggcttaccca ctgctgcacg gttgtaccgt tacgcttttt gatcaagaag caaacgccgc
    87721 cgtgatgttc cgtgcctgac gcttttgtca attccgcttc atccaccaca tggtacgctt
    87781 tgcggtttgc cgccatccag cgcaaggctt ctttaaaacg tggcgttacg ctctggataa
    87841 accaggcgcg aacaatcgct tccggacggc tctggaacag tgcctgacat gcattttcgc
    87901 cgtagacgcg ggtttcttcc gcacgctgac gacgcaaaac ttctggatca atataacttt
    87961 taccactgat gccaccgtga tcggcctttt ccggcgtctc atcacccggc gcgcgggaaa
    88021 ccgtgcgcca cggcgaatct tcccacttgc ggtcacgggg ctgactctgt ttgtcatcgc
    88081 gggcggggcg acggccaccg tcagcacgag attttcctgg acgcccgccc cctttcccgg
    88141 tacgcgggtt gtgggtacgt ttatcagaat catcatcact gcggacatac atcactttga
    88201 ccttgccgct tttacctttc atttcatcgt tcatgctttt ctccaccagc gctgcgcgaa
    88261 gcgcgcagat tacccgaagt ccgcgcggtt cgccatgatt tcgtaccaaa gcctgcgact
    88321 atcataccta ttgaataaaa cagattgttg tctggaacaa tgtccccgat aatatgtaac
    88381 atattagaaa cataccggcg tcgttgccga taagtctcct tactcatccc gaggttagtt
    88441 atgaataccg tttgtaccca ttgtcaggcc atcaatcgca ttcccgacga tcggatcgaa
    88501 gatgcggcaa aatgcggacg ctgcggtcac gacttgtttg acggagaggt gattaatgcg
    88561 accggtgaaa cactcgacaa attgctgaag gatgatctac ctgtggtgat cgacttctgg
    88621 gcaccgtggt gcggcccctg ccgtaatttc gcaccaattt ttgaagatgt cgcgcaagag
    88681 cgtagcggta aagtgcgctt tgtgaaagtg aataccgaag ctgaacgtga attgagcagt
    88741 cgctttggaa ttcgtagtat accgacgatc atgattttca aaaacggtca ggttgtcgac
    88801 atgcttaatg gcgcagtacc gaaagcgccg ttcgacagct ggctgaacga atctctttaa
    88861 tcttaccggg gcgcatcttg tgccccgttt tctcctctgc gacaatggcg ttttttcgac
    88921 gctctcttat gaccgaaaac gctgttctcc agttacgcgc cgagcgtatt gcgcgcgcaa
    88981 cacgtccttt tcttgcccgc ggtaatcgcg ttcgtcgctg ccaacgctgt cttttgccag
    89041 agaaattatg tctctgttcg acaattaccc cagcacaagc aaaaagtcgc ttctgtttgc
    89101 tgatgttcga caccgagcca atgaagccca gtaataccgg gcgtctgatt gctgatattt
    89161 tgcctgatac cgttgcgttt caatggtcgc gtaccgaacc ctcgcaggat ttgctggatc
    89221 tggtacaaaa cccggactat caaccaatgg tggtctttcc cgcctcgtat gctgatgagc
    89281 aacgggaagt gatcttcaca ccacctgccg gtaagccacc gctgtttatc atgctcgatg
    89341 gtacctggcc ggaagctcgc aagatgtttc gtaaaagtcc gtatctggat aatcttcccg
    89401 tcatttccgt cgatctttcc cggctttctg cctatcgcct gcgtgaagcc caggctgaag
    89461 gccaatattg tactgccgag gtagccatcg cactgttaga tatggccggc gataccgggg
    89521 cggcggcagg gttaggcgag cattttaccc gctttaaaac acgctatctg gcaggaaaaa
    89581 cgcaacatct gggtagcatc acagcagaac agttagaaag cgtttaaaat cattcggtca
    89641 cttctgcggg agaccggtat gagtcagcga ggactggaag cactactgcg accaaaatcg
    89701 attgcggtaa ttggcgcatc gatgaaaccc aatcgcgcag gttacctgat gatgcgtaac
    89761 ctgctggcgg gaggctttaa cggaccggta ctcccggtga cgccagcctg gaaagcggtg
    89821 ttgggtgtgt tggcctggcc ggatattgcc agcttgccct ttacacccga ccttgcggtt
    89881 ttatgtacta atgccagccg taatcttgct cttctggaag agctcggcga gaaaggctgt
    89941 aaaacctgca ttattctttc cgccccggca tcgcaacacg aagatctccg cgcctgcgcc
    90001 ctgcgccata acatgcgcct gctaggacca aacagtctgg gtttactggc tccctggcaa
    90061 ggtctgaatg ccagcttttc gcctgtgccg attaaacgcg gcaagctggc gtttatttca
    90121 caatcggctg ccgtctccaa caccatcctc gactgggcgc aacagcgtga gatgggcttt
    90181 tcctacttta ttgcgctcgg cgacagcctg gatatcgacg ttgatgaatt gctcgactat
    90241 cttgcgcgcg acagtaaaac cagcgccatc ctgctctatc tcgaacagtt aagcgacgcg
    90301 cgacgctttg tttcggcggc ccgtagtgcc tcgcgtaata aaccgattct ggtgattaaa
    90361 agcggacgta gcccggcggc acagcgactg ctcaacacga cggcaggaat ggatccggcg
    90421 tgggatgcgg ctattcagcg tgccggtttg ttgcgggtac aggacaccca cgagctgttt
    90481 tcggcggtgg aaacccttag ccatatgcgc ccgctgcgtg gcgaccggtt gatgattatc
    90541 agcaacggtg ctgcgcctgc cgcgctggcg ctggatgcct tatggtcaca caatggcaag
    90601 ctggcaacgc taagcgaaga aacctgccag aaactgcgcg atgcactgcc tggacatgtg
    90661 gcaatctcta acccgctcga tctgcgcgat gacgccagca gcgagcatta tgtcaaaacg
    90721 ctggacattc tgctccacag ccaggatttt gatgcgctga tggttattca ttcacccagc
    90781 gcagcggctc ccgcaacaga aagcgcgcaa gaattaattg aagcggtaaa gcatcatccc
    90841 cgcagcaaat atgtctcttt gctgacgaac tggtgcggcg agcactcctc gcaagaggca
    90901 cgacgtttat tcagcgaagc cgggctgccg acctatcgca cgccggaagg caccatcacc
    90961 gcgtttatgc atatggtgga gtaccggcgt aatcagaagc aactacgcga aacgccggcg
    91021 ttgcccagca atctgacttc caataccgca gaagcgcatc ttctgttgca acaggcgatt
    91081 gccgaagggg ctacgtcgct cgatacccat gaagttcagc ctatcctgca agcgtatggc
    91141 atgaacacgc tccccacctg gattgccagc gatagcaccg aagcggtgca tattgccgaa
    91201 cagattggtt atccggtggc gctgaaattg cgttcgccgg atattccaca taaatcggaa
    91261 gttcagggcg taatgctgta cctgcgtaca gccaatgaag tccagcaagc ggcaaacgct
    91321 attttcgatc gcgtaaaaat ggcatggccg caggcgcgga tccacggcct gttggtgcaa
    91381 agtatggcta accgggctgg cgctcaggag ttgcgggttg tggttgagca cgatccggtt
    91441 ttcgggccgt tgatcatgct gggtgaggaa ggtgtggagt ggcgtcctga agatcaagcc
    91501 gtcgtcgcac tgccgccgct gaacatgaac ctggcccgct atctggttat tcaggggatc
    91561 aaaagtaaaa agattcgtgc gcgcagtgcg ctacgcccat tggatgttgc aggcttgagc
    91621 cagcttctgg tgcaggtttc caacctgatt gtcgattgcc cggaaattca gcgtctggat
    91681 attcatcctt tgctggcttc tggcagtgaa tttaccgcgc tggatgtcac gctggatatc
    91741 gcgccgtttg aaggcgataa cgagagtcgg ctggcagtgc gcccttatcc gcatcagctg
    91801 gaagaatggg tagaattgaa aaacggtgaa cgctgcttgt tccgcccgat tttgccagaa
    91861 gatgagccac aacttcagca attcatttcg cgagtcacca aagaagatct ttattaccgc
    91921 tactttagcg agatcaacga atttactcat gaagatttag ccaacatgac gcagatcgac
    91981 tacgatcggg aaatggcgtt tgtagcggta cgacgtattg atcaaacgga agagatcctc
    92041 ggcgtcacgc gtgcgatctc cgaccctgat aacatcgatg ccgaatttgc tgtgctggtt
    92101 cgctcggatc tcaaagggtt aggcttaggt cgacgcttaa tggaaaagtt gattacctat
    92161 acgcgagatc acggactaca acgtctgaat ggtattacga tgccaaacaa tcgtggcatg
    92221 gtggcgctag cccgcaagct cgggtttaac gttgatatcc agctcgaaga ggggatcgtt
    92281 gggcttacgc taaatcttgc ccaacgcgag gaatcatgag taaggtactg gaaatgttga
    92341 ccacttaatc gggactggtg ttattattgc ccgcttatgt cgtctgcatt gcacagagga
    92401 cccttcaatg aacagagaag aaatgcactg tgatgttgtc aaaatttaag cgtaataaac
    92461 atcaacaaca ccttgcccaa ctacccaaga tttctcaatc agttgatgat gtcgatttct
    92521 tttacgctcc cgccgacttc cgggagacgc tgctggaaaa aatagccagc gcgaagcagc
    92581 gcatttgcat tgtcgccctg tatctcgaac aggatgacgg tggcaaaggc attctgaacg
    92641 cgttgtatga agctaaaagg cagcgtccgg aactggatgt gcgggtgctg gtcgactggc
    92701 atcgtgcaca acgtggacgc attggcgctg cggcatctaa cactaacgct gactggtact
    92761 gccgcatggc gcaggaaaat ccgggcgtag atgttccggt ttatggcgtt ccaatcaata
    92821 cccgtgaagc ccttggtgtt ctgcacttta aaggctttat catcgacgat agcgtacttt
    92881 atagcggtgc cagcctgaac gatgtttacc tgcatcagca cgataaatat cgctacgacc
    92941 gttatcatct tatccgtaac cgtaagatgt cagacattat gtttgaatgg gttacacaga
    93001 atattatgaa tggccgcggc gttaatcgtc tggatgatgt taatcggcca aaaagcccgg
    93061 aaatcaagaa cgatattcgt ctgttccgcc aggagctgcg tgatgccgct tatcatttcc
    93121 agggcgatgc cgacaacgat cagctttccg taacgccgct agtggggctg gggaaatcga
    93181 gtctgttgaa caagaccatt ttccatctta tgccttgtgc cgagcagaaa ctaaccatct
    93241 gtacgccata cttcaacctg ccagcaatcc ttgtgcgcaa tattatccag ttgctgcgcg
    93301 aagggaaaaa ggtcgaaatt attgttggtg ataaaaccgc gaacgacttc tacattccgg
    93361 aagatgaacc tttcaagata attggcgcat tgccttatct ctatgagatc aatctgcgtc
    93421 gtttcctgag ccgtttgcag tattacgtca atactgacca gctagtggtt cggttatgga
    93481 aagatgacga caacacctat cacctaaaag ggatgtgggt tgatgataag tggatgttga
    93541 tcaccggtaa taacctgaac ccgcgcgcct ggcgtctgga tctggaaaac gccattttga
    93601 tccacgatcc gcaacttgag ctggcgccac agcgagagaa agaactggag ctgatccgcg
    93661 agcataccac catcgttaag cactatcgcg atctgcaaag tattgccgat tatccggtga
    93721 aggttcgtaa actcatccgc cgtttgcgcc gtatccgcat cgaccgatta attagccgca
    93781 tcctgtaatc acaaccccgt cctgtacggg gtttgttttt tggaggccac gttttgcgta
    93841 ttctttttgt ctgttcgcta ttgttacttt ctggatgcag ccatatggct aacgatagct
    93901 ggagcgggca ggataaagct caacacttta tcgcctcggc gatgctttcc gccgccggaa
    93961 atgaatattc acagcatcag gggatgagcc gggatcgcag tgccatgttt ggattgatgt
    94021 tctctgtcag tttgggggcg tcaaaagagc tttgggatag ccgccccgaa gggagcggct
    94081 ggagctggaa ggatttggcc tgggatgtcg ccggtgcaag caccggctat accgtctggc
    94141 aactgacccg tcactaaaga cgcatcccct tccctttgcg atgtagcatc aaagaaacca
    94201 gaaacgccac cacggccatc aaggtcacat accagaagaa ggctgtttcc attcctattg
    94261 atttcagcga caacgctacg tactccgccg aaccaccaaa tatagcatta gcgaccgcat
    94321 atgacaggcc aacgcctaat gcgcgaacct gtgccgggaa catctcagcc ttcagtattc
    94381 cactgattga tgtataaaaa ctcactatca gcagggcaca catcaccaga ccaaaagcgg
    94441 cataaggcga ggaaacgttt tgcaatgctg agagaatagg aacggtaaaa atggctgcca
    94501 gcgaaccgaa acataacatt gaggtacggc gaccaatctt atccgacagc gcgccaatga
    94561 gtggttgaat aagcatgaat acaaacaatg cggcagtcat aatgccactc gccacgttgg
    94621 catgcattcc cgcagtattt accagatact tctgcatata agtggtgaag gtatagaaac
    94681 aaagggagcc cgcagcggta aaaccgagaa ccatgatgaa tgcacggcga ttgcgccata
    94741 atcctttcag agatccagct tcttttaaag cgcgcgtttc ttgttgcgaa gtttcatcta
    94801 actgacgacg taaccacaac gccacaacag ctaacacagc tcctaacgcg aaaggaatac
    94861 gccatcccca ctctctgagt gcagcgtctt ccatggtgtg ttgtaaaacc acgacaacca
    94921 gtagggctag cagttgtccg ccgatcaacg tcacatactg aaatgatgcg taaaaacctt
    94981 tgcgcccttc aacggcaact tcactcatat aggtggcgct ggtgccatat tctccgccaa
    95041 cggataatcc ctgaaataaa cgcgcgagaa gcaataatgc cggagcccac gtacctatag
    95101 tttcataacc tgggaggcag gcgataacca gcgatccgaa acacatcata cacaccgata
    95161 acagcatcga ttttttgcga ccatgtttat cggctatgcg gccaaatagc caaccgccta
    95221 ttgggcgcat caggaatccc gcagcaaaaa cacctgctgt ttgtagtagt tgagtcgtcg
    95281 tgttcccgga agggaagaaa atgtgggcaa agtagagtga acagaacgag tagacataga
    95341 aatcgaacca ctcgaccaga ttacctgaag aggcccccac aatcgcccaa atgcggcgac
    95401 gagtatcact acttgtcagt ttgctgtctg ccgttacagt actttcagcc atgccattat
    95461 gtctcctgcc gtaatccgat gcttttgtcg gtcgctttta tctatttctt ttggtaaaga
    95521 aaatgttata catttgttgc gtatcattat gcaaccttaa ccatgaattt agttagcagg
    95581 aaaatggtta ttgaggagct taaggataaa tttctggtaa ggaggacacg tatggaagta
    95641 ggcaagttgg ggaaaccgca tccgttgctg aatctggcat atgtgcgagt ataagacgcg
    95701 cagcgtcgca tcaggcattt ttttctgcgc caacgcaaaa aggccatcgt gactgatggc
    95761 cttt
//
LOCUS       DAPGUL010000005        88322 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.005, whole genome shotgun sequence.
ACCESSION   DAPGUL010000005 DAPGUL010000000
VERSION     DAPGUL010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 88322)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 88322)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..88322
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.005"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(109..771)
                     /gene="dedD"
                     /locus_tag="RHX21_000359"
     CDS             complement(109..771)
                     /gene="dedD"
                     /locus_tag="RHX21_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311225.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DedD"
                     /protein_id="HDV1985601.1"
                     /translation="MASKFQNRLVGTIVLVALGVIVLPGLLDGQKKHYQDEFAAIPLV
                     PKAGDRDEPDMMPAATQALPTQPPEGAAEEVRAGDAAAPSLDPATIAANNTEFEPEPA
                     PVVPPKPKPVEPPKPKVEAPPAPKPEPKPVVEEKAAPTGKAYVVQLGALKNADKVNEI
                     VGKLRGAGYRVYTSPSTPVQGKITRILVGPDASKDKLKGSLGELKQLSGLSGVVMGYT
                     PN"
     gene            complement(761..2029)
                     /gene="folC"
                     /locus_tag="RHX21_000360"
     CDS             complement(761..2029)
                     /gene="folC"
                     /locus_tag="RHX21_000360"
                     /EC_number="6.3.2.12"
                     /EC_number="6.3.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tetrahydrofolate
                     synthase/dihydrofolate synthase"
                     /protein_id="HDV1985602.1"
                     /translation="MIIKRTPQAASPLASWLSYLENLHSKTIDLGLERVSQVAARLGV
                     LKPAPFVFTVAGTNGKGTTCRTLESILMAAGYKVGVYSSPHLVRYTERVRVQGKELPE
                     SAHTASFAEIESARGDISLTYFEYGTLSALWLFKQAQLDVVILEVGLGGRLDATNIVD
                     ADVAVVTSIALDHTDWLGPDRESIGREKAGIFRSEKPAIVGEPEMPSTIADVAQEKGA
                     LLQRRGVEWNYSVTDHDWAFSDAHGTLENLPLPLVPQPNAATALAALRASGLEVSENA
                     IRDGIASAILPGRFQIVSESPRVIFDVAHNPHAAEYLTGRMKTLPKNGRVLAVIGMLH
                     DKDIAGTLAWLKSVVDDWYCAPLEGPRGATAEQLLEHLGNGKSFDSVAQAWDAAMADA
                     KAEDTVLVCGSFHTVAHVMEVIDARRSGGK"
     gene            complement(2099..3013)
                     /gene="accD"
                     /locus_tag="RHX21_000361"
     CDS             complement(2099..3013)
                     /gene="accD"
                     /locus_tag="RHX21_000361"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HDV1985603.1"
                     /translation="MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLE
                     VCPKCDHHMRMTARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKET
                     GEKDALVVMKGTLYGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLICFS
                     ASGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNI
                     AEPKALIGFAGPRVIEQTVREKLPPGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAK
                     LMNLPAPNPEAPREGVVVPPVPDQEPEA"
     gene            complement(3169..3828)
                     /locus_tag="RHX21_000362"
     CDS             complement(3169..3828)
                     /locus_tag="RHX21_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDV1985604.1"
                     /translation="MDLIYFLIDFILHIDVHLAELVAEYGVWVYAILFLILFCETGLV
                     VTPFLPGDSLLFVAGALASLETNDLNVHMMVVLMLIAAIVGDAVNYTIGRLFGEKLFS
                     NPNSKIFRRSYLDKTHQFYEKHGGKTIILARFVPIVRTFAPFVAGMGHMSYRHFAAYN
                     VIGALLWVLLFTYAGYFFGTIPMVQDNLKLLIVGIIVVSILPGVIEIIRHKRAAARAA
                     K"
     gene            complement(3911..4723)
                     /gene="truA"
                     /locus_tag="RHX21_000363"
     CDS             complement(3911..4723)
                     /gene="truA"
                     /locus_tag="RHX21_000363"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDV1985605.1"
                     /translation="MSDQQQPPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALS
                     QVANEPITVFCAGRTDAGVHGTGQVVHFETTAQRKDAAWTLGVNANLPGDIAVRWVKA
                     VPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGEND
                     FTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHN
                     QPESWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRYDLPKPPMGPLFLAD"
     gene            complement(4723..5736)
                     /locus_tag="RHX21_000364"
     CDS             complement(4723..5736)
                     /locus_tag="RHX21_000364"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HDV1985606.1"
                     /translation="MSEGWNIAVLGATGAVGEALLETLAERQFPVGEIYALARNESAG
                     EQLRFGGKTITVQDAAEFDWTQAQLAFFVAGKEATAAWVEEATNSGCLVIDSSGLFAL
                     EPDVPLVVPEVNPFVLTDYRNRNVIAVPDSLTSQLLAALKPLIDQGGLSRISVTSLIS
                     ASAQGKKAVDALAGQSAKLLNGIPIDEEDFFGRQLAFNMLPLLPDSEGSVREERRIVD
                     EVRKILQDEGLMISASVVQAPVFYGHAQMVNFEALRPLAAEEARDAFVQGEDIVLSEE
                     NEFPTQVGDASGTPHLSVGCVRNDYGMPEQVQFWSVADNVRFGGALMAVKIAEKLVQE
                     YLY"
     gene            complement(5802..6959)
                     /gene="pdxB"
                     /locus_tag="RHX21_000365"
     CDS             complement(5802..6959)
                     /gene="pdxB"
                     /locus_tag="RHX21_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020218743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-phosphoerythronate dehydrogenase PdxB"
                     /protein_id="HDV1985607.1"
                     /translation="MSETEKGLKILVDENMPYARDLFSRLGEVIAVPGRPIPVAQLAD
                     ADALMVRSVTKVNESLLAGKPIKFVGTATAGTDHVDEAWLKKAGIGFSAAPGCNAIAV
                     VEYVLSSLLMLAERDGFSLHDRTVGIVGVGNVGRRLQARLEALGIKTLLCDPPRADRG
                     DEGDFRSLDELVQHADILTFHTPLFKDGPYKTLHLADEKLIRNLKPGAILINACRGAV
                     VDNTALLTCLNEGQKLSVVLDVWEGEPELNVELLTKVDIGTPHIAGYTLEGKARGTTQ
                     VFEAYSKFIGHEQHIALDTLLPAPEFGRITLHGPLDQPTLKRLVHLVYDVRRDDAPLR
                     KVAGIPGEFDKLRKNYLERREWSSLYVICDDASAASLLCKLGFNAVHHPAR"
     gene            complement(7119..8123)
                     /locus_tag="RHX21_000366"
     CDS             complement(7119..8123)
                     /locus_tag="RHX21_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001709053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDV1985608.1"
                     /translation="MSIKKLEDGRYLLDIRPNGRKGKRVRKVFDKKSVAVATERYIMA
                     NAEKREYIQGYRDRRTLNDLLELWWMYHGQHRRKAEEDRKQLRNIISELGADMQAVDL
                     DKLKIIAWRSQKIAAGLKPSSANRYMNRLSGMFTVLKRIGLWDAEHPVRGISILYVSP
                     REMAFLSQKEVALLLDTLEGDYWRVALLCLSTGARWSEACKLRGEQIVHNRVTFLETK
                     NGRKRTVPISQAVCEAIKTRETGSLFEVKYREFCLALKRVKPDLPKGQAAHVLRHTFA
                     SHFVMNGGNIIALQKILGHATIQQTMAYAHFAPDYLQDAVALNPLKGGVSVHAVSTGD
                     "
     gene            complement(8220..8540)
                     /locus_tag="RHX21_000367"
     CDS             complement(8220..8540)
                     /locus_tag="RHX21_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDV1985609.1"
                     /translation="MIHKSSLGEKLRLIREAEGLSRREMEEVTGVSQNNLKNYEILGR
                     MIPGETLLLILNHPRFRKYSDWVMFNQTNAATGQIAPPLSLDGFFDSEGDQVSTETNQ
                     KSPR"
     gene            8656..8943
                     /locus_tag="RHX21_000368"
     CDS             8656..8943
                     /locus_tag="RHX21_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1985610.1"
                     /translation="MSESELEGFIQVAPYPLEAVPYQLFAKMIGRKESTVRTMIDAAK
                     LPTIDFVKPGSVKTRASENWVYLPAFNAGMRKAFFDQPKERRDAWLLWLGL"
     gene            8950..9156
                     /locus_tag="RHX21_000369"
     CDS             8950..9156
                     /locus_tag="RHX21_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1985611.1"
                     /translation="MTSNITSAILTLVFIEIGVIAIYLFRKLTGHEERFIELSIEYIA
                     AYTKGLFPAAIGAMFIAFVIWFIG"
     gene            9409..9750
                     /locus_tag="RHX21_000370"
     CDS             9409..9750
                     /locus_tag="RHX21_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4761 family protein"
                     /protein_id="HDV1985612.1"
                     /translation="MKQQRNSRFRNGAERHANRFATSASRSNIRYSLSDTHATPDGYP
                     VKQIGEHTWLIEKAGIVLHKCPRNPFTGNRIFALSSGDNQFGQDFTLYEALRTVDRLL
                     RGQSFIKQADL"
     gene            9761..10048
                     /locus_tag="RHX21_000371"
     CDS             9761..10048
                     /locus_tag="RHX21_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1985613.1"
                     /translation="MTKDHAQGVFIRFIDFRGELLLRASAIDGVTPAGKNGADEATYV
                     YLNGTRLLVELPYQTVREIISEAEKARQVNGDEAYIEIICMDSEAEIQKAD"
     gene            10060..10302
                     /locus_tag="RHX21_000372"
     CDS             10060..10302
                     /locus_tag="RHX21_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4754 family protein"
                     /protein_id="HDV1985614.1"
                     /translation="MGKEYKTLINKALERFYFRLSASGAHTERAARDSLTRAIRSLYD
                     VAFYADDLDALNELSELICAAECGEHIEPYKLGNIA"
     gene            10299..10412
                     /locus_tag="RHX21_000373"
     CDS             10299..10412
                     /locus_tag="RHX21_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1985615.1"
                     /translation="MSIFISWLVLIISVACAIGIMRIINSVKKIERFFSDE"
     gene            10506..10916
                     /locus_tag="RHX21_000374"
     CDS             10506..10916
                     /locus_tag="RHX21_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001376666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1985616.1"
                     /translation="MHAKEEGIIRALKEISKMESEVAKKAVANAHMDVATHTMIVAKV
                     TAEAAKIIEEQGVELALLKTKPVTGLDLSDTGRLIYTIGSEPQRYTIIAGLQNKYLIT
                     PHPIRESALLTNLRLIERSQVAFIDDARHTVFNA"
     gene            10940..11143
                     /locus_tag="RHX21_000375"
     CDS             10940..11143
                     /locus_tag="RHX21_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1985617.1"
                     /translation="MAIKHFPVVRFTSRGREYEVDERLITTIDKHRSEKDAHHIYLTD
                     GTYFCATNVARVNLIRQVQEPRR"
     gene            11140..11406
                     /locus_tag="RHX21_000376"
     CDS             11140..11406
                     /locus_tag="RHX21_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDV1985618.1"
                     /translation="MTILDYIATHPGCSGGEIAAALNTPTTAINAELRQLWRGGLVIR
                     TNRSTGGRARKTGGQASYHVNPMPFGCSNPLTHMFNQLLKEART"
     gene            11403..11702
                     /locus_tag="RHX21_000377"
     CDS             11403..11702
                     /locus_tag="RHX21_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1985619.1"
                     /translation="MSTINHQKLRELAFALQRMATPQKLLAFRAMLSPSAVLALLDEL
                     EHARTTAPAIRLTLHHEIADFCATLEAPGEPETPEAIQQELLQRIDKVFDFFLNQ"
     gene            11714..12331
                     /locus_tag="RHX21_000378"
     CDS             11714..12331
                     /locus_tag="RHX21_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001372767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ash family protein"
                     /protein_id="HDV1985620.1"
                     /translation="MHTQKNRLPCRNQSGYISAAPHKTGAGILNPIQSKAHNRASGFF
                     VRTVLPRLFRVRIMAGRTGPTSVGPDSLLSGVENPVRLATPRFSTLDGELFLSPSKEA
                     TPWQTANNSAHTLRVVTSRLKSTVDFSAHHASRKSCTSICCMSAATRYRTSIPPLFSA
                     IWRMICASCNNSSSSKTNSINSCSGPFLHLAAGGLRTSVVKRIAA"
     gene            12328..12717
                     /locus_tag="RHX21_000379"
     CDS             12328..12717
                     /locus_tag="RHX21_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001534315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase"
                     /protein_id="HDV1985621.1"
                     /translation="MIDAHDFTRWVRTQDTRLAPVLQGLFDLYIRGRDNRARTTKPEN
                     ADTLYFTVDDCYRVDFTPHGLALHCLTPHGESLLAYYDSPASVFAAMLAHRTAGGCAS
                     LSEYTAEFNRLSALFSQEWQRVTGYQP"
     gene            12714..15554
                     /locus_tag="RHX21_000380"
     CDS             12714..15554
                     /locus_tag="RHX21_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001685010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication endonuclease"
                     /protein_id="HDV1985622.1"
                     /translation="MSEFAWSWNEPRPAIDPARFTEHRQETETDLQRAIRYYLEADKK
                     AREEQEAKEEAFFAQSAMGKKLMASLEEAGQREKLAQSIISKRRATEQDPVARAFATL
                     KALPVYLREPLSRHLSFLRKKQEADRQKGKKSWQAERYARGTLRKIFERLDRTDSRWL
                     TPGYRSLAGRERLDDLLYLPQLNKHQIQTLATMTAAMFSSTFEKLCDGFGATDGELTM
                     DVTLKAYQMLARMALHLHAMPPHYDALTTDKDRRNEPDTELLPGAILRLTCAEWWKRK
                     LWLLRCEWREEQLRAACLVSRKTSPYLSQDALSEFRAQREKTRDFLKSFMLENEDGFT
                     IDLETVYYAGVSNPVHRKAEMMATMKGLELLAEARGDKAVFLTVTCPSKYHATTENGH
                     PNPKWNGATMRDSSDYLVNTFFAAVRKKLNRDGLRWYGIRTVEPHHDGTVHWHMMVFA
                     HPEEIDTIVSHTRDIAIQEDRHELGDDITPRFKAEYVDGSKGTPTSYIATYIGKNLDS
                     RAVDGIDPKTGKPRVDHETGKSMAESVERAIGWARLHRVRQFQFFGIPSRQVWRELRR
                     LASQMARNPEGPQRLKDDAMDAVLAAADAGCFATYIEKQGGVLVPRKDYLIRTAYDLA
                     DELNDYGEQSVQIYGIWSPLIGESSRVCTHPDNWKLVRRKPEAEDSARENGFDLQGGP
                     AAPWTRGNNCPRAQETDNNGTEQPEERPAPWPQLPDGIEVNEWMRSLKRHERRALMRS
                     LRDKQAKNSSDEMQSWTQSRKQQRPLPDNHELLAREWRESAESLGLHIGEQQMQHLLR
                     GGSLYVDGSIIAPQGFEIVRKPDTRPDSRITQLWQRLSRNHGVSSTEIRHNPVASYLA
                     QLGASDPEAATRLASTLQQDQNTMKTPVTALSDMLRAIRDAEHAQRISETTERARRKA
                     DLLRGGLTSGNKKQTETGLTNPVNEQKTRSDI"
     gene            15631..16590
                     /locus_tag="RHX21_000381"
     CDS             15631..16590
                     /locus_tag="RHX21_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid segregation protein ParM"
                     /protein_id="HDV1985623.1"
                     /translation="MKICIDDGSTNIKLAWTENGERRNAISPNSFKSEWSAPFGGTQP
                     ANYMLDGVRYGFDPVSDRFVQTTDTQYQYSDVNVIAIHHALVKSGITPQEVDVVVTLP
                     LSEYFDTNAQPDMANISRKKANVMRPVEYQNGEAFTIRNVRVMPESIPAGFKALADMS
                     PFESLLIVDLGGTTLDVAKVQGQLAGISQVFCDPHVGVSLMADAVLSVMATNGMRTSH
                     HIANTIIEHRHDEAWLRQHIHNDAHYDSLMAVIREKEETLKQRVIRALAGFSGYGRVM
                     VVGGGAEIVAPAIREACGVNATFIADGVPQFALVNGLYAMDKE"
     gene            16595..16906
                     /locus_tag="RHX21_000382"
     CDS             16595..16906
                     /locus_tag="RHX21_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012907691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid partitioning/stability family protein"
                     /protein_id="HDV1985624.1"
                     /translation="MTTPTRRISFYLKPVAVKNEGEACAWLDSLTPEARKSGQRVAFL
                     AGLALLKMNPAEAYRLAAWADDEALSVTQTRTERPVSQPVPTTQITSQMAGNIRALFP
                     E"
     gene            16967..17491
                     /locus_tag="RHX21_000383"
     CDS             16967..17491
                     /locus_tag="RHX21_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1985625.1"
                     /translation="MKKYEYMLMKEALRAGLAPCPVSVEAVVGNTIFRTLRNRVSVKM
                     IHQPPKSTSMIYLPLPEAIKLMRSLKFAIWMQTQLNKAVQNTFVKKLMPELAARCAKC
                     TRPALQFDLSLIQQATEAELYRLSPLHDAHTEASEMFRLMFQFNFAVRRTRVQVNRMM
                     QAQEELAQHKGGNQ"
     gene            17488..18078
                     /locus_tag="RHX21_000384"
     CDS             17488..18078
                     /locus_tag="RHX21_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ead/Ea22-like family protein"
                     /protein_id="HDV1985626.1"
                     /translation="MSKIDYQALRERYSPAPVPKCPICGEEMSIQRISGAQVVYACSG
                     YGDDGDFKIGRTLADEHYEKSRVTVLDVGDPEVLALLDWLETKDNRIAELEKIATDYA
                     LKFQKAQDALKYAALLHSRTAQQTNNFAVSLPDISEYFINDVFQPLRYERDVERAIIK
                     AGGKALWQEKHEDRTHQSCDVNCGWFSPLTTDKNNT"
     gene            complement(18569..19615)
                     /locus_tag="RHX21_000385"
     CDS             complement(18569..19615)
                     /locus_tag="RHX21_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001706445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDV1985627.1"
                     /translation="MSRKNKKVRMSSRIDLADALRKESSLSAFTFDGPYRLTGHDLLD
                     NMYCADNGRWYETPVDWYGLARAARQTSWHQSALYFKRNVLLGCYIPHPLLSRQDFSA
                     LALDWFVFGNAFLELRSNMLGEPLKLRHALAKYMRRGSDLESWWYVQDGKDAFQFRPG
                     KVCHLMNPDINQEIYGMPEYLGALLSASLSHSADMFRKLYYDNGSHAGCIIYIGAAQV
                     NRESMDSLKETLQGARGGGAFKNVLIHAPNGGKEGVQILPFQQITAKDEFMNVKAASR
                     DDVLAAHRVPPQLMGAMPGEKSAFGDVEKAARVYAINELMPVMEAMKHINDWLGEEVI
                     RFNPYALLDTQPTS"
     gene            complement(19615..21366)
                     /locus_tag="RHX21_000386"
     CDS             complement(19615..21366)
                     /locus_tag="RHX21_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001737206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase family protein"
                     /protein_id="HDV1985628.1"
                     /translation="MIQDAFVRQRARQLYWQGYPPAEISRLMGINPNTIYAWKKRDQW
                     DETPPVQRVTQSIDARLIQLTEKQNKTGGDFKEIDLLTRQLKKLHDGQPDATATGKKG
                     RAKKLKNHFTPEQIAALREKIISRLEWHQRGWFDSLTLCREAGIRNRMILKSRQIGAT
                     WYFAQEALLMALRDDVAQPYQRNQIFLSASRRQAFQFKSIIQKAAAEVDVELKGGDKI
                     ILSNGAELHFLGTSAASAQSYTGNFYFDEFFWVSRFAELRKVAGAMATLSGLRRTYFS
                     TPSTETHEAYAYWNGDRWNEKKATHKRQRFSVDWKTLHNGLICPDRTWRQIVTLEDVV
                     KHGWKHTDIDEIRDENTEDEFLNLYMCEFVREGESAFNLNILIGCGVDGYDDWKDWKP
                     FAPRPMGNRPVWIGYDANGSSGNGDSGAVSVVVPPAVPGGRFRTVETRRVQGLEFEEQ
                     ARVIEEFTCRYNVEHIGIDVTGGNGEAVYQIVKRFFPAAIPYTFTLSSKRSLVLKMLQ
                     IMRTGRWEYDRAERELVAAFNAVRKVKTPGGFITYETDRARGISHGDLAWATMLAVIN
                     EPIGGEGENERFTVMEF"
     gene            21521..22357
                     /locus_tag="RHX21_000387"
     CDS             21521..22357
                     /locus_tag="RHX21_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPO family capsid scaffolding protein"
                     /protein_id="HDV1985629.1"
                     /translation="MANEKKTSRKKFRVAVSGVTADGREINGDMLKAAATSYNPSVYG
                     ARVNIEHILSPLPGSEFSAMGDVVGLSTEDITDGPLAGRTALYAEIEPTARMMSLLND
                     GKKIYSSIELEPQSTITGGPYLRGLAMTDTPASLGTERLAFAAQQRMQLMTFNCQQGD
                     VAMFTAAMESELIELTEQRQEEGTQWFNRVMGIIGRGRKADDASFSRIQEAVEGVATS
                     QADIIDRFNVLETRHQQDSQKITLLTTELAALKEKLRTQDGDPQNRFTATGAASDQLA
                     DF"
     gene            22381..23433
                     /locus_tag="RHX21_000388"
     CDS             22381..23433
                     /locus_tag="RHX21_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020218748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein, P2 family"
                     /protein_id="HDV1985630.1"
                     /translation="MNLVMSDITRNKLGCYMAQQASLNNIPVSALVSRFTVEPSVQQR
                     FENASKESTEFTKRINVIGVTDQKGEKILLDTTGPIARTNTSYDGTKRRNPNNVVDLK
                     NRKYQCEQVNYDTFISYPQLDAWAAHPDFQSRISAQIARQVALDRIMIGFNGTSHSDE
                     SNFSTNKLLQDVNVGWLEHIRTDASERVMNDVTLTSRNMDNTVAHAGKYANADALVQD
                     ARSSLLDEWHKEADDLVVIMGRNLFNSLRLPVLNSISGQNPNAELLAGQLILSSRTIG
                     GLGVFLAPFFPDSTMLITSFNNLSIYWQKGSMRRLMKDEPEYNRIATYQSINDAYVVE
                     DYGKCAMVTGLKFADS"
     gene            23479..24279
                     /locus_tag="RHX21_000389"
     CDS             23479..24279
                     /locus_tag="RHX21_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000632360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HDV1985631.1"
                     /translation="MITPAQQHWQNVMAQRAGRANEGVDHAARTAHEEVLYRLRLAQA
                     RLKGVQARSAKAAIKKELLPDFSGWIEGTLEADGGQQDEVIATLMVWAIDCGDLPLAL
                     RIGAYVVRHNLIMPDNFGRTAATVLTEEICNPVLTQAGTDADADLSAFIEPLDTLWEI
                     VANQDMPDEVRAKLCKACAFARRGLSDADSMASSLKLLREAMHLNPNAGVKREIATLS
                     RALKKADSAAAPEDASTPQTQDESSKSKKTTRKPATRKTTATQKAKRG"
     gene            24383..24877
                     /locus_tag="RHX21_000390"
     CDS             24383..24877
                     /locus_tag="RHX21_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head completion/stabilization protein"
                     /protein_id="HDV1985632.1"
                     /translation="MSMVARTEPRPAEDDITDTDDGDTRISAGAFWPDIVLRELRLAV
                     RLPGRVTTSRLLHTATGAVAHVTRELEAWQQEQQAAGHQTLADVPAPVINGESVNLWH
                     WRNAVYTATRALILERYRDADTTDKGDRRADALDIQTSDLWRDVSWAISDILCRPRIF
                     AELC"
     gene            24877..25077
                     /locus_tag="RHX21_000391"
     CDS             24877..25077
                     /locus_tag="RHX21_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail protein X"
                     /protein_id="HDV1985633.1"
                     /translation="MKVKALEGDTVDSLCFRYYGTTQGVTEKVLDANPGLCQQVFLDA
                     GQDVEMPEPEKKKREMIQLWGE"
     gene            25080..25403
                     /locus_tag="RHX21_000392"
     CDS             25080..25403
                     /locus_tag="RHX21_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000104349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDV1985634.1"
                     /translation="MSTIQTGITEQVIAWLFDHLPTVYAAGAAVSISALMSLYDGRTL
                     VQTVTGSLACGVLAMAVAGSLRFFGVPEDAVTFFGASIGFMGAEKARDKIIAAFNRIT
                     QKGDE"
     gene            25458..26003
                     /locus_tag="RHX21_000393"
     CDS             25458..26003
                     /locus_tag="RHX21_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001493236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 108 protein"
                     /protein_id="HDV1985635.1"
                     /translation="MKSKDEIFDAVLGKEGGYVNHPADRGGPTKWGITEKVARAHGYR
                     GDMRDLTRGQALEILEADYWYGPRFDQIAKLSPDIAAELCDTGVNMGPSVATRMLQRW
                     LNAFNQGGKLYPDMDTDGRTGPRTINALRAYLEKRGRDGEMVMLTALNCTQGERYLEL
                     AEKREANESFVYGWIKERVAA"
     gene            26000..26407
                     /locus_tag="RHX21_000394"
     CDS             26000..26407
                     /locus_tag="RHX21_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2570 domain-containing protein"
                     /protein_id="HDV1985636.1"
                     /translation="MKLWTSLGVAFLLIAAWGTSMRLSWSLGRENARNEAQASTLKST
                     VDTLNIISTGVQDMQQVLAQLRVENQQRNQDGEARREQLRNDIAKDECAHALPDARFT
                     DRLRRHAERATASAVSPAYTADADHTGNASPLP"
     gene            26545..27012
                     /locus_tag="RHX21_000395"
     CDS             26545..27012
                     /locus_tag="RHX21_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV1985637.1"
                     /translation="MLKTDSLREAMTRSCRWCQANPEKFTIFVESGNIETTGETPSFV
                     YRYQMVMFVMDYAGELDDLTLPLLAWLSENQPQLLLNPERNQDIKFSAVINDDDSADL
                     LFTLPLRERVRITRNSQGTPQAEHLPEPKPRLPSSEGDWSHVFQDVTWGESDG"
     gene            27005..27640
                     /locus_tag="RHX21_000396"
     CDS             27005..27640
                     /locus_tag="RHX21_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage virion morphogenesis protein"
                     /protein_id="HDV1985638.1"
                     /translation="MDKAFTRVDETFEAIRDSLNQQAINNIARKLAQDLRRAQQARIR
                     SQKAPDGTAWTPRRRRVTRIQERIRFIWNNEVRTLKNWHHDTGKYGRTITGWDEDKNN
                     IRTFYRDDIDRFLEIRTRRINQDSTKRVPMFVKLRTARYLKARADASGVTVGYSGVAA
                     RIARVHQFGERDQVAPGIFTDYPVRELLGISQADERLIYNTVLGRIAEAVR"
     gene            27652..28218
                     /locus_tag="RHX21_000397"
     CDS             27652..28218
                     /locus_tag="RHX21_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HDV1985639.1"
                     /translation="MRLLSNIIRTGIISEVDEKSWRVRVRSGELETGWLRWNTTRAGA
                     FNVWLPPSPGEQVVIACIGGNPETAMIIGSLWSDANPAPGKSLKEIVISAPDGAVFRY
                     DADAGALSASGMKTATLQASVSVKLDTPVVECTNLLRTATLDVTKGGKMSGNITHSGG
                     NFTSNGITVHTHKHGGVKGGSDSTGGPQ"
     gene            28236..28565
                     /locus_tag="RHX21_000398"
     CDS             28236..28565
                     /locus_tag="RHX21_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001705832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPW/gp25 family protein"
                     /protein_id="HDV1985640.1"
                     /translation="MNPDGTGNLNDMEHLKQSVRDILTTPLASRVMRREYGSLVPDLI
                     DEPMNNTTRLQCMSAAVIALTRWEPRIALDAIDVVWKAGGRAGVTLSGTVMQTMQNVE
                     LTITLRE"
     gene            28569..29465
                     /locus_tag="RHX21_000399"
     CDS             28569..29465
                     /locus_tag="RHX21_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001297572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HDV1985641.1"
                     /translation="MPAVDLSQLPDPAIIAEPDFEAILADTKAMMIAAYPAEQREAVS
                     AALELESEPLNVIAQTTAFREMLLRQRVNEGARACMLSHSAGADLDNLAGNMNTKRLV
                     ITPATDTTDAVMESDTSLRLRAQRAYDGLSVAGPSGAYEYFARSASGLVHDARAISPF
                     PANVTVSILSTEGDGTATEALLNTVRAVLNAEDTRPVADRLTVQSARIVTWRLNAKLY
                     FYPGPESEPILAAAESSFRKWLAEQGLIGQDVALSAIAAALHVHGVQRVEIIEPTQNM
                     AISDIQAARCESFTISEGGRNE"
     gene            29458..30066
                     /locus_tag="RHX21_000400"
     CDS             29458..30066
                     /locus_tag="RHX21_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein I"
                     /protein_id="HDV1985642.1"
                     /translation="MSNSLLPPSASNFMRCAEAVGTRITDIPVDLNTLWSPDTCPVHL
                     LPYLAWAFSVDRWDRNWPEETKRQVIRDAWLIHRHKGTISALRRAVEPLGYLIEVKEW
                     WQLNEEPGTFRIVVGVLDQGITDEMYQELERLIADAKPVSRHLTGLAISLSVNGNIFV
                     GTGCYHGDALTVYPYTPESIIVEGDYFPAPAIHLIDNLRVNA"
     gene            30063..31778
                     /locus_tag="RHX21_000401"
     CDS             30063..31778
                     /locus_tag="RHX21_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001518691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV1985643.1"
                     /translation="MTVKYYAILTNQGAARLANATMLGSKLNLTQMAVGDANGVLPTP
                     DPAQTKLINQKRIAPLNLLSVDPNNQSQIIAEQIIPENEGGFWIREIGLYDDEGVLIA
                     VANCPETYKPQLQEGSGRTQTIRMILVVTNTEAITLKIDPSVVLATRKYVDDKISEHE
                     QSRRHPDASLTAKGFTQLSSATNSTSETLAATPKAVKIAYDLANGKYTAQDATTARKG
                     LVQLSSATSSTSETQAATPKAVKAAYDLAAGKAPVSHTHPWSQITDVPAASLTVKGTV
                     QLSSATNSTSETQAATPKAVKAAYDLANGKQPADATLTALAGLATAADKLPYFTGNDT
                     ANLTTLTNVGRDILAKTSKQEVIHYLGLGATNGYVGRLVNTRVFTSSGTYTPTPGTKR
                     IRVTITGGGGGGGGCKAISNNETFFGAGGGAGGTIISIMTPTQNSYPVTIGAGGAGGV
                     SATNGTRGGNSVFASLIAPGGAGGGKSGVTNTNGGSGGVPSTGGINIIGGNGGDGQSG
                     NIGVSGEGGTSYWGGGGRAGAGGGVSGKAYGSGGGGAYDAGYSGTSMTGGKGAAGICI
                     IEEFA"
     gene            31778..32188
                     /locus_tag="RHX21_000402"
     CDS             31778..32188
                     /locus_tag="RHX21_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000994390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HDV1985644.1"
                     /translation="MNASYAVIENGMVVNVIVWDGEAEFTVPDNQQLIDISDISEHPG
                     IGWGYSDGVFTAPLPPERSHDELVADAEQKKQSLIDAAMANISVIQLKLQAGRKLTQE
                     ETTRLNVVLDYIDAVTATDTSTAPDVIWPELPEA"
     gene            complement(32160..32600)
                     /locus_tag="RHX21_000403"
     CDS             complement(32160..32600)
                     /locus_tag="RHX21_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HDV1985645.1"
                     /translation="MNYIYSATTNSFYPLEMKEDYTQADSWPDDAVEVDEQAYIEFSG
                     LPPKGKIRIAGENGFPAWSEIPPPTHEEQIAAAELEKQQLINQANDYMNSKQWAGKAA
                     IGRLKGEELAQYNLWLDYLDALELVDTSSGPDIEWPTPPAVQAR"
     gene            complement(32622..33011)
                     /locus_tag="RHX21_000404"
     CDS             complement(32622..33011)
                     /locus_tag="RHX21_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001568588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1985646.1"
                     /translation="MPFACYFCIFINVGLGEAAKRNVGTGTNQIPDMGSFTLSVSGTG
                     YQKLPSGFILQWGSIGAPGIAQDVVTHFPIAFPNRCLRVLVSQDYTPDSGSVGYIACA
                     GFSSDPVKFISRASTPGLGASFLALGC"
     gene            33041..33163
                     /locus_tag="RHX21_000405"
                     /pseudo
     CDS             33041..33163
                     /locus_tag="RHX21_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308311.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(33265..35154)
                     /locus_tag="RHX21_000406"
     CDS             complement(33265..35154)
                     /locus_tag="RHX21_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016239642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HDV1985647.1"
                     /translation="MKSETLTVQQLFQDRRQYCVPFYQRAYVWTQQDQWSALLEDILE
                     KAQSRLSGTKPTPHFLGAVVLEPQSKKGLLGVDSIHIIDGQQRLTTLQYVLASIRLAL
                     RATDLFSLEALISPCLKNSNEDTMRNKEVERFKLWPTFRDQTHFIQSFNVENIDDLRD
                     VFSDSFTQHGTLRKHFNHPPSLEALCFFTEAFIKWIKIENHSPQENAVALIEAVLTDL
                     KLVSIFLEAEDDAQIIFETLNGRGAELHATDLIRNYIFMCAEHENINAIELYENEWKS
                     FEDKYWSEKQRRGRINKPRMEWLVHATLQSERQREIDLSRLYNEYRDYVSKDLSSQRA
                     DLQVKRLKQYASQYKELVDGFGTTPISHFGYRIADYDVTTLYPLALFISIANIADDEK
                     AAMYNDLVSYVVRRAVCGLTPKNYNNVFMNVLRHLSKTEISSVELRNILNSLNGEASR
                     WPGDSEFLNACINAPLYPGRLDAPKMRSMLTELERELCRQVKTEKPDGPNLSNLDIDH
                     LMPQSWFSCWPLENGHMVTNSDATVLNQIVLSGTDLTPEQLLVRKRQQAIATLGNLTL
                     LNLSVNRSVQNAVFLKKRDALIVHTNLRLNIPLIVKDKWDEDEILERGKKLGEIALKV
                     WPKHD"
     gene            complement(35540..35756)
                     /locus_tag="RHX21_000407"
                     /pseudo
     CDS             complement(35540..35756)
                     /locus_tag="RHX21_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311510.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DinI-like family protein"
     gene            complement(35998..36074)
                     /locus_tag="RHX21_000408"
     tRNA            complement(35998..36074)
                     /locus_tag="RHX21_000408"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(36038..36040),aa:Pro,seq:ggg)
     gene            complement(36149..37909)
                     /gene="pbgA"
                     /locus_tag="RHX21_000409"
     CDS             complement(36149..37909)
                     /gene="pbgA"
                     /locus_tag="RHX21_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin transport protein PbgA"
                     /protein_id="HDV1985648.1"
                     /translation="MVTHRQRYREKVSQMVSWGHWFALFNILLSLVIGSRYLFIADWP
                     TTLAGRIYSYVSIIGHFSFLVFATYLLILFPLTFIVGSQRLMRFLSVILATAGMTLLL
                     IDSEVFTRFHLHLNPIVWQLVINPDENEMARDWQLMFISVPVILLLELVFATWSWQKL
                     RSLTRRRRFARPLAAFLFIAFIASHVVYIWADANFYRPITMQRANLPLSYPMTARRFL
                     EKHGLLDAQEYQRRLIEQGNPDAVSVQYPLSELRYRDMGTGQNVLLITVDGLNYSRFE
                     KQMPALAGFAEQNISFTRHMSSGNTTDNGIFGLFYGISPSYMDGILSTRTPAALITAL
                     NQQGYQLGLFSSDGFTSPLYRQALLSDFSMPSVRTQSDEQTATQWINWLGRYAQEDNR
                     WFSWVSFNGTNIDDSNQQAFARKYSRAAGNVDDQINRVLNALRDSGKLDNTVVIITAG
                     RGIPLSEDEETFDWSHGHLQVPLVIHWPGTPAQRINALTDHTDLMTTLMQRLLHVSTP
                     ASEYSQGQDLFNPQRRHYWVTAADNDTLAITTPKKTLVLNNNGKYRTYNLRGERVKDE
                     KPQLSLLLQVLTDEKRFIAN"
     gene            complement(37929..38156)
                     /locus_tag="RHX21_000410"
     CDS             complement(37929..38156)
                     /locus_tag="RHX21_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YejL family protein"
                     /protein_id="HDV1985649.1"
                     /translation="MPQISRYSDEQVEQLLAELLNVLEKHKAPTDLSLMVLGNMVTNL
                     INTSIAPAQRQAIANSFARALQSSINEDKAH"
     gene            38338..39345
                     /gene="yejK"
                     /locus_tag="RHX21_000411"
     CDS             38338..39345
                     /gene="yejK"
                     /locus_tag="RHX21_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein YejK"
                     /protein_id="HDV1985650.1"
                     /translation="MSLDINQIALHQLIKRDEQNLELVLRDSLLEPTETVVEMVAELH
                     RVYSAKNKAYGLFSEESELAQTLRLQRQGEEDFLAFSRAATGRLRDELAKYPFADGGF
                     VLFCHYRYLAVEYLLVAVLSNLSSMRVNENLDINPTHYLDINHADIVARIDLTEWETN
                     PESTRYLTFLKGRVGRKVADFFMDFLGASEGLNAKAQNRGLLQAVDDFTAEAQLDKAE
                     RQNVRQQVYSYCNEQLQAGEEIELESLSKELAGVSEVSFTEFAAEKGYELEESFPADR
                     STLRQLTKFAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTPPNLRDQLQRRTSGG
                     N"
     gene            complement(39484..39768)
                     /gene="rplY"
                     /locus_tag="RHX21_000412"
     CDS             complement(39484..39768)
                     /gene="rplY"
                     /locus_tag="RHX21_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000494192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25"
                     /protein_id="HDV1985651.1"
                     /translation="MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAIELDH
                     DKVMNMQAKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLQHIDFVRA"
     gene            complement(39893..41653)
                     /locus_tag="RHX21_000413"
     CDS             complement(39893..41653)
                     /locus_tag="RHX21_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDV1985652.1"
                     /translation="MIFTLRPYQQEAVDATLNHFRRHKTPAVIVLPTGAGKSLVIAEL
                     ARLARGRVLVLAHVKELVAQNHAKYQALGLEADIFAAGLKRKESHGKVVFGSVQSVAR
                     NLDAFQGEFSLLIVDECHRIGDDEESQYQQILTHLTKVNPHLRLLGLTATPFRLGKGW
                     IYQFHYHGMVRGDEKALFRDCIYELPLRYMIKHGYLTPPERLDMPVVQYDFSRLQAQS
                     NGLFSEADLNRELKKQQRITPHIISQIMEFAEKRKGVMIFAATVEHAKEIVGLLPAED
                     AALITGDTPGAERDVLIEDFKAQRFRYLVNVAVLTTGFDAPHVDLIAILRPTESVSLY
                     QQIVGRGLRLAPGKTDCLILDYAGNPHDLYAPEVGTPKGKSDNVPVQVFCPACGFANT
                     FWGKTTADGTLIEHFGRRCQGWFEDDDGHREQCDFRFRFKNCPQCNAENDIAARRCRE
                     CDTVLVDPDDMLKAALRLKDALVLRCSGMSLQHEHDEKGEWLKITYYDEDGADVSERF
                     RLQTPAQRTAFEQLFIRPHTRTPGIPLRWITAADILAQQALLRHPDFVVARMKGQYWQ
                     VREKVFDYEGRFRRAHELRG"
     gene            41802..42497
                     /gene="rsuA"
                     /locus_tag="RHX21_000414"
     CDS             41802..42497
                     /gene="rsuA"
                     /locus_tag="RHX21_000414"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase RsuA"
                     /protein_id="HDV1985653.1"
                     /translation="MRLDKFIAQQLGVSRAIAGREIRGNRVTVDGEIVRNAAFKLLPE
                     HDVAYDGNPLAQQHGPRYFMLNKPQGYVCSTDDPDHPTVLYFLDEPVAWKLHAAGRLD
                     IDTTGLVLMTDDGQWSHRITSPRHHCEKTYLVTLESPVADDTAEQFAKGVQLHNEKDL
                     TKPAVLEVITPTQVRLTISEGRYHQVKRMFAAVGNHVVELHRERIGGITLDADLAPGE
                     YRPLTEEEIASVV"
     gene            42525..43715
                     /gene="bcr"
                     /locus_tag="RHX21_000415"
     CDS             42525..43715
                     /gene="bcr"
                     /locus_tag="RHX21_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Bcr"
                     /protein_id="HDV1985654.1"
                     /translation="MTTRQHSSFAIVFILGLLAMLMPLSIDMYLPALPVISAQFGVPA
                     GSTQMTLSTYILGFALGQLIYGPMADSFGRKPVVLGGTLVFAAAAVACALANTIDQLI
                     VMRFFHGLAAAAASVVINALMRDIYPKEEFSRMMSFVMLVTTIAPLMAPIVGGWVLVW
                     LSWHYIFWILALAAILASAMIFFLIKETLPPERRQPFHIRTTIGNFAALFRHKRVLSY
                     MLASGFSFAGMFSFLSAGPFVYIEINHVAPENFGYYFALNIVFLFVMTIFNSRFVRRI
                     GALNMFRSGLWIQFIMAAWMVISALLGLGFWSLVVGVAAFVGCVSMVSSNAMAVILDE
                     FPHMAGTASSLAGTFRFGIGAIVGALLSLATFNSAWPMIWSIAFCASSSILFCLYASR
                     PKKR"
     gene            44048..44392
                     /locus_tag="RHX21_000416"
     CDS             44048..44392
                     /locus_tag="RHX21_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1985655.1"
                     /translation="MTSLQLSIVHRLPQNYRWSAGFAGSKVEPIPQNGPCGDNSLVAL
                     KLLSPDGDNAWSVMYKLSQALSDIEVPCSVLECEGEPCLFVNRQDEFAATCRLKNFGV
                     AIAEPFSNYNPF"
     gene            complement(44396..45985)
                     /gene="yejF"
                     /locus_tag="RHX21_000417"
     CDS             complement(44396..45985)
                     /gene="yejF"
                     /locus_tag="RHX21_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin C ABC transporter ATP-binding protein
                     YejF"
                     /protein_id="HDV1985656.1"
                     /translation="MTQTLLAIENLSVGFRHQQTVRTVVNDVSLQIEAGETLALVGES
                     GSGKSVTALSILRLLPSPPVEYLSGDIRFHGESLLHASDQTLRGVRGNKIAMIFQEPM
                     VSLNPLHTLEKQLYEVLSLHRGMRREAARGEILNCLDRVGIRQAAKRLTDYPHQLSGG
                     ERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQGELNMGMLFITHNLS
                     IVRKLAHRVAVMQNGRCVEQNYAATLFASPTHPYTQKLLNSEPSGDPVPLPEPASTLL
                     DVEQLQVAFPIRKGILKRIVDHNVVVKNISFTLRAGETLGLVGESGSGKSTTGLALLR
                     LINSQGSIIFDGQPLQNLNRRQLLPIRHRIQVVFQDPNSSLNPRLNVLQIIEEGLRVH
                     QPTLSAAQREQQVIAVMHEVGLDPETRHRYPAEFSGGQRQRIAIARALILKPSLIILD
                     EPTSSLDKTVQAQILTLLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQG
                     PCARVFATPQQEYTRQLLALS"
     gene            complement(45987..47012)
                     /locus_tag="RHX21_000418"
     CDS             complement(45987..47012)
                     /locus_tag="RHX21_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV1985657.1"
                     /translation="MSRLSPVNQARWARFRHNRRGYWSLWIFLVLFGLSLCSELIAND
                     KPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQDPWLKQRLENNGWVLWAPIRFGA
                     TSINFATDKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVL
                     AGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSL
                     VGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTL
                     TSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAILLSLLIFIGEAVRDA
                     FDPNKAV"
     gene            complement(47012..48106)
                     /locus_tag="RHX21_000419"
     CDS             complement(47012..48106)
                     /locus_tag="RHX21_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin C ABC transporter permease YejB"
                     /protein_id="HDV1985658.1"
                     /translation="MGAYLIRRLLLVIPTLWAIITINFFIVQIAPGGPVDQAIAAIEF
                     GNAGVLPGAGGEGIRASHAQTGVGNISDSNYRGGRGLDPEVIAEITHRYGFDKPIHER
                     YFKMLWDYIRFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAV
                     YNGSRFDVWSSAFIIIGYAIPAFLFAILLIVFFAGGSYFDLFPLRGLVSANFDSLPWY
                     QKITDYLWHITLPVLATVIGGFAALTMLTKNSFLDEVRKQYVVTARAKGVSEKNILWK
                     HVFRNAMLLVIAGFPATFISMFFTGSLLIEVMFSLNGLGLLGYEATVSRDYPVMFGTL
                     YIFTLIGLLLNIVSDISYTLVDPRIDFEGR"
     gene            complement(48107..49921)
                     /locus_tag="RHX21_000420"
     CDS             complement(48107..49921)
                     /locus_tag="RHX21_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311096.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDV1985659.1"
                     /translation="MIVRILLLFIALFTFGAQAQAIKESYAFAVLGEPRYAFNFNHFD
                     YVNPAAPKGGQITLSALGTFDNFNRYALRGNPGARTEQLYDTLFTTSDDEPGSYYPLI
                     AESARYADDYSWVEVAINPRARFHDGSPITARDVEFTFRKFMTEGVPQFRLVYKGTTV
                     KAIAPLTVRIELAKASKEDMLSLFSLPVFPEKYWKDHKLSDPLATPPLASGPYRVTSW
                     KMGQNIVYSRVKDYWAANLPVNRGRWNFDTIRYDYYLDDNVAFEAFKAGAFDLRMEND
                     AKNWATRYTGKNFDKKYIIKDEQKNESAQDTRWLAFNIQRPVFSDRRVREAITLAFDF
                     EWMNKALFYNAWSRTNSYFQNTEYAARNYPDAAELVLLAPMKKDLPPEVFTQIYQPPV
                     SKGDGYDRDNLLKADKLLNEAGWVLKGQQRVNATTGQPLSFELLLPASSNSQWVLPFQ
                     HSLQRLGINMDIRKVDNSQITNRMRSRDYDMMPRVWRAMPWPSSDLQISWSSEYINST
                     YNAPGVQSPVIDSLINQIIAAQGNKEKLLPLGRALDRVLTWNYYMLPMWYMAEDRLAW
                     WDKFSQPAVRPVYSLGIDTWWYDVNKAAKLPSARQQGE"
     gene            complement(50003..51559)
                     /locus_tag="RHX21_000421"
     CDS             complement(50003..51559)
                     /locus_tag="RHX21_000421"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-GMP phosphodiesterase"
                     /protein_id="HDV1985660.1"
                     /translation="MFIRAPNSGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYD
                     TLITDVQKYLDTYFADLKSTTDRLQPLTLDTCQQANPELTARAAFSMNVRTFVLVKDK
                     KTFCSSATGEMDIPLNELIPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSG
                     VFAALNLNLTPSLFYSSRQEDYDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIA
                     GIPLTVRLYADDWTWNDVWYAFLLGGMSGTVVGLLCYYLMSVRMRPGREIMTAIKREQ
                     FYVAYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAESQKMIVPLTQHLFEL
                     IARDAAELEKVLPVGVKFGINIAPDHLHSESFKADIQKLLTSLPAHHFQIVLEITERD
                     MLKEQEATQLFAWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRGFINAIGTET
                     ITSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLSERGVNFMQGYWISRPLPLDDFVR
                     WLKKPYTPQW"
     gene            complement(51740..52306)
                     /gene="mepS"
                     /locus_tag="RHX21_000422"
     CDS             complement(51740..52306)
                     /gene="mepS"
                     /locus_tag="RHX21_000422"
                     /EC_number="3.4.17.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional murein DD-endopeptidase/murein
                     LD-carboxypeptidase"
                     /protein_id="HDV1985661.1"
                     /translation="MVKSQPILRYILRGIPAIAVAVLLSACSANNTAKNMHPETRVVG
                     SETSSLQASQDEFENLVRNVDVKSRIMDQYADWKGVRYRLGGSTKKGIDCSGFVQRTF
                     REQFGLELPRSTYEQQEMGKSVSRSNLRTGDLVLFRAGSTGRHVGIYIGNNQFVHAST
                     SSGVIISSMNEPYWKKRYNEARRVLSRS"
     gene            complement(52718..53431)
                     /gene="lpxT"
                     /locus_tag="RHX21_000423"
     CDS             complement(52718..53431)
                     /gene="lpxT"
                     /locus_tag="RHX21_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311093.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Kdo(2)-lipid A phosphotransferase"
                     /protein_id="HDV1985662.1"
                     /translation="MIKNLPQIVLLNIVGLALFLSWYIPVNHGFWLPIDADIFYFFNQ
                     KLVESKAFLWLVALTNNRAFDGCSLLAMGMLMLSFWLKENAPGRRRIVIIGLVMLLTA
                     VVLNQLGQALIPVKRASPTLTFTDINRVSELLSVPTKDASRDSFPGDHGMMLLIFSAF
                     MWRYFGKVAGLIALIIFVVFAFPRVMIGAHWFTDIIVGSMTVILIGLPWVLLTPLSDR
                     LITFFDKSLPGKNKHFQNK"
     gene            complement(53470..54456)
                     /gene="yeiR"
                     /locus_tag="RHX21_000424"
     CDS             complement(53470..54456)
                     /gene="yeiR"
                     /locus_tag="RHX21_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding GTPase YeiR"
                     /protein_id="HDV1985663.1"
                     /translation="MTRTNLITGFLGSGKTTSILHLLAHKDPNEKWAVLVNEFGEVGI
                     DGALLADSGALLKEIPGGCMCCVNGLPMQVGLNTLLRQGKPDRLLIEPTGLGHPKQIL
                     DLLTAPVYEPWIDLRATLCILDPRLLLDEKSASNENFRDQLAAADIIVANKSDRATPE
                     SEQALQRWWQQNGGDRQLIHSEHGKVDGHLLDLPRRNLAELPASAAHSHQHVVKKGLA
                     ALSLPEHQRWRRSLNSGQGYQACGWIFDADTVFDTIGILEWARLAPVERVKGVLRIPE
                     GLVRINRQGDDLHIETQNVAPPDSRIELISSSEADWNALQSALLKLRLATTA"
     gene            complement(54574..56040)
                     /locus_tag="RHX21_000425"
     CDS             complement(54574..56040)
                     /locus_tag="RHX21_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HDV1985664.1"
                     /translation="MKTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLT
                     DRVMNAQGGDWGICEISLFSGDQLMSQLRAQNHLYTVLEKGADGNQVIIVGAVHECLN
                     AKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQTPEEPHS
                     APGILVEALKRRRERGLTPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHV
                     SFPGTMVDRIVPAATDESLAEISQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVA
                     GVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDCMQDRAFRHAARTLMLNE
                     QAPTLQIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHLGCE
                     TDWSLLALGVAGWMRYVSGVDDAGNAIDVRDPLSDKIRELVAGSSSEQRVTALLSLRE
                     VFGDDLPDNPHFVQAIEQAWQQIVQFGAHQALLNTLKI"
     gene            complement(56263..56835)
                     /gene="yeiP"
                     /locus_tag="RHX21_000426"
     CDS             complement(56263..56835)
                     /gene="yeiP"
                     /locus_tag="RHX21_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007750416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P-like protein YeiP"
                     /protein_id="HDV1985665.1"
                     /translation="MPRANEIKKGMVLNYNGKLLLVKDIDIQSPTARGAATLYKMRFS
                     DVRTGLKVEERFKGDDIVDTVTLTRRYVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEE
                     ELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLST
                     GLVIQVPEYLSPGEKIRIHIEERRYMGRAD"
     gene            56990..57244
                     /locus_tag="RHX21_000427"
     CDS             56990..57244
                     /locus_tag="RHX21_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HDV1985666.1"
                     /translation="MKCRPGCGACCTAPSISSPIPGMPDGKPANTPCIQLDEQQRCKI
                     FTSPLRPKVCAGLQASAEMCGNSRQQAMTWLIDLEMLTAP"
     gene            complement(57241..58422)
                     /gene="setB"
                     /locus_tag="RHX21_000428"
     CDS             complement(57241..58422)
                     /gene="setB"
                     /locus_tag="RHX21_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter SetB"
                     /protein_id="HDV1985667.1"
                     /translation="MHNSPAVSSAKSFDLTSTAFLIVAFLTGIAGALQTPTLSIFLTD
                     EVHARPAMVGFFFTGSAVIGILVSQFLAGRSDKRGDRKSLIVFCCLLGVLACTLFAWN
                     RNYFVLLFVGVFLSSFGSTANPQMFALAREHADKTGREAVMFSSFLRAQVSLAWVIGP
                     PLAYALAMGFSFTVMYLSAAVAFIVCGVMVWLFLPSMQKELPLATGTIEAPRRNRRDT
                     LLLFVICTLMWGSNSLYIINMPLFIINELHLPEKLAGVMMGTAAGLEIPTMLIAGYFA
                     KRLGKRFLMRVAAVGGVCFYAGMLMAHSPVILLGLQLLNAIFIGILGGIGMLYFQDLM
                     PGQAGSATTLYTNTSRVGWIIAGSVAGIVAEIWNYHAVFWFAMVMIIATLFCLLRIKD
                     V"
     gene            58790..59920
                     /gene="fruB"
                     /locus_tag="RHX21_000429"
     CDS             58790..59920
                     /gene="fruB"
                     /locus_tag="RHX21_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused PTS fructose transporter subunit IIA/HPr
                     protein"
                     /protein_id="HDV1985668.1"
                     /translation="MFQLSVQDIHPGEKAGDKEEAIRQVAAALVQAGNVAEGYVNGML
                     AREQQTSTFLGNGIAIPHGTTDTRDQVLKTGVQVFQFPEGVTWGDGQVAYVAIGIAAS
                     SDEHLGLLRQLTHVLSDDSVAEQLKSATTAEELRALLMGEKQSEQLKLDNEMLTLDIV
                     ASDLLTLQALNAARLKEARAVDATFVTKAINEQPLNLGQGIWLSDSAEGNLRSAIAVS
                     RAANAFDVDGETAAMLVSVAMNDDQPIAVLKRLADLLLDNKADRLLKADAATLLALLT
                     SDDAPTDDVLSAEFVVRNEHGLHARPGTMLVNTIKQFNSDITVTNLDGTGKPANGRSL
                     MKVVALGVKKGHRLRFTAQGADAEQALKAIGDAIAAGLGEGA"
     gene            59920..60858
                     /gene="fruK"
                     /locus_tag="RHX21_000430"
     CDS             59920..60858
                     /gene="fruK"
                     /locus_tag="RHX21_000430"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDV1985669.1"
                     /translation="MSRRVATITLNPAYDLVGFCPEIERGEVNLVKTTGLHAAGKGIN
                     VAKVLKDLGIDVTVGGFLGKDNQDGFQQLFSELGIANRFQVVQGRTRINVKLTEKDGE
                     VTDFNFSGFEVTPADWERFVTDSLSWLGQFDMVCVSGSLPSGVSPEAFTDWMTRLRSQ
                     CPCIIFDSSREALVAGLKAAPWLVKPNRRELEIWAGRKLPEMKDVIEAAHALREQGIA
                     HVVISLGAEGALWVNASGEWIAKPPSVDVVSTVGAGDSMVGGLIYGLLMRESSEHTLR
                     LATAVAALAVSQSNVGITDRPQLAAMMARVDLQPFN"
     gene            60875..62566
                     /gene="fruA"
                     /locus_tag="RHX21_000431"
     CDS             60875..62566
                     /gene="fruA"
                     /locus_tag="RHX21_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIBC"
                     /protein_id="HDV1985670.1"
                     /translation="MKTLLIIDANLGQARAYMAKTLLGAAARKAKLEIIDNPNDAEMA
                     IVLGDSIPNDSALNGKNVWLGDISRAVAHPELFLSEAKGHAKPYTAPVTATAPVAASG
                     PKRVVAVTACPTGVAHTFMAAEAIETEAKKRGWWVKVETRGSVGAGNAITPEEVAAAD
                     LVIVAADIEVDLAKFAGKPMYRTSTGLALKKTAQELDKAVAEATPYEPAGKTQTATTE
                     GKKESAGAYRHLLTGVSYMLPMVVAGGLCIALSFAFGIEAFKEPGTLAAALMQIGGGS
                     AFALMVPVLAGYIAFSIADRPGLTPGLIGGMLAVSTGSGFIGGIIAGFLAGYIAKLIS
                     TQLKLPQSMEALKPILIIPLISSLVVGLAMIYLIGKPVAGILEGLTHWLQTMGTANAV
                     LLGAILGGMMCTDMGGPVNKAAYAFGVGLLSTQTYGPMAAIMAAGMVPPLAMGLATMV
                     ARRKFDKAQQEGGKAALVLGLCFISEGAIPFAARDPMRVLPCCIVGGALTGAISMAIG
                     AKLMAPHGGLFVLLIPGAITPVLGYLVAIIAGTLVAGLAYAFLKRPEVDAVAKAA"
     gene            62990..63931
                     /locus_tag="RHX21_000432"
     CDS             62990..63931
                     /locus_tag="RHX21_000432"
                     /EC_number="2.7.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine kinase"
                     /protein_id="HDV1985671.1"
                     /translation="MREKDYVVIIGSANIDVAGYSHESLNYADSNPGKIKFTPGGVGR
                     NIAQNLALLGNKAWLLSAVGSDFYGQSLLTQTNQSGVYVDKCLIVPGENTSSYLSLLD
                     NTGEMLVAINDMNISNAITAEYLAQHREFIQRAKVIVADCNISEEALAWILDNAANVP
                     VFVDPVSAWKCVKVRDRLNQIHTLKPNRLEAETLSGIALSGRDDVAKVAAWFHQHGLN
                     RLVLSMGGDGVYYSDISGENGWSAPIKTNVINVTGAGDAMMAGLASCWVDGMPFAESV
                     RFAQGCSSMALSCEYTNNPDLSIANVISLVENAECLN"
     gene            63919..64857
                     /gene="psuG"
                     /locus_tag="RHX21_000433"
     CDS             63919..64857
                     /gene="psuG"
                     /locus_tag="RHX21_000433"
                     /EC_number="4.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine-5'-phosphate glycosidase"
                     /protein_id="HDV1985672.1"
                     /translation="MSELKISPELLQISPEVQDALKNKKPVVALESTIISHGMPFPQN
                     AQTAIEVEETIRKQGAVPATIAIIGGVMKVGLSKEEIELLGREGHNVTKVSRRDLPFV
                     VAAGKNGATTVASTMIIAALAGIKVFATGGIGGVHRGAEHTFDISADLQELANTNVTV
                     VCAGAKSILDLGLTTEYLETFGVPLIGYQTKALPAFFCRTSSFDVSIRLDSASEIARA
                     MAVKWQSGLNGGLVVANPIPEQFAMPEESINAAIDQAVAEAEEQGVIGKESTPFLLAR
                     VAELTGGDSLKSNIQLVFNNAILASEIAKEYQRLAG"
     gene            64951..66201
                     /locus_tag="RHX21_000434"
     CDS             64951..66201
                     /locus_tag="RHX21_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HDV1985673.1"
                     /translation="MDIMRSVVGMVVLLAIAFLLSVNKKSISLRTVGAALLLQIAIGG
                     IMLYFPPGKWAVEQAALGVHKVMSYSDAGSAFIFGSLVGPKMDVLFDGAGFIFAFRVL
                     PAIIFVTALISLLYYIGVMGLLIRILGSIFQKALNISKIESFVAVTTIFLGQNEIPAI
                     VKPFIDRMNRNELFTAICSGMASIAGSMMIGYAGMGVPIDYLLAASLMAIPGGILFAR
                     ILSPATEPSQVTFENLSFSETPPKSFIEAAASGAMTGLKIAAGVATVVMAFVAIIALI
                     NGIIGGIGGWFGFANASLESIFGYVLAPLAWIMGVDWSDANLAGSLIGQKLAINEFVA
                     YLNFSPYLQTSGTLDVKTIAIISFALCGFANFGSIGVVVGAFSAISPKRAPEIAQLGL
                     RALAAATLSNLMSATIAGFFIGLA"
     gene            complement(66272..66970)
                     /gene="yeiL"
                     /locus_tag="RHX21_000435"
     CDS             complement(66272..66970)
                     /gene="yeiL"
                     /locus_tag="RHX21_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311082.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator YeiL"
                     /protein_id="HDV1985674.1"
                     /translation="MKEIHNNDLKQQLMSESAFKDCFLTDVSADTRLFHFLARDYIVQ
                     EGQQPSWLFYLTRGRARLYATLANGRVSLIDFFAAPCFIGEIELIDKDHEPRAVQAIE
                     ECWCLALPMKHYRPLLLNDTLFLRKLCVTLSHKNYRNIVSLTQNQSFPLVNRLAAFIL
                     LSQEGDLYHEKHTQAAEYLGVSYRHLLYVLAQFIHDGLLTKSKKGYLIKNRKQLSGLA
                     LEMDPENKFSGMMQ"
     gene            67100..68041
                     /gene="rihB"
                     /locus_tag="RHX21_000436"
     CDS             67100..68041
                     /gene="rihB"
                     /locus_tag="RHX21_000436"
                     /EC_number="3.2.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosylpyrimidine nucleosidase"
                     /protein_id="HDV1985675.1"
                     /translation="MEKRKIILDCDPGHDDAIAMMMAAKHPAIDLLGITIVAGNQTLD
                     KTLINGLNVCQKLEINVPVYAGMPQPIMRKQIVADNIHGETGLDGPVFEPLTRQAEST
                     HAVKYIIDTLMASDGDITLVPVGPLSNIAVAMRMQPAILPKIREIVLMGGAYGTGNFT
                     PSAEFNIFADPEAARVVFTSGVPLVMMGLDLTNQTVCTPDVIARMERAGGPAGELFSD
                     IMNFTLKTQFENYGLAGGPVHDATCIGYLINPDGIKTQEMYVEVDVNSGPCYGRTVCD
                     ELGVLGKPANTKVGITIDTDWFWGLVEECVRGYIKTH"
     gene            68141..69391
                     /locus_tag="RHX21_000437"
     CDS             68141..69391
                     /locus_tag="RHX21_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HDV1985676.1"
                     /translation="MDVMRSVLGMVVLLAIAFLLSVNKKKISLRTVGAALVLQVVIGG
                     IMLWLPPGRWVAEKVAFGVHKVMAYSDAGSAFIFGSLVGPKMDTLFDGAGFIFGFRVL
                     PAIIFVTALVSILYYIGVMGILIRILGGIFQKALNISKIESFVAVTTIFLGQNEIPAI
                     VKPFIDRLNRNELFTAICSGMASIAGSTMIGYAALGVPVEYLLAASLMAIPGGILFAR
                     LLSPATESSQVSFNNLSFTETPPKSIIEAAATGAMTGLKIAAGVATVVMAFVAIIALI
                     NGIIGGVGGWFGFAHASLESILGYLLAPLAWVMGVDWSDANLAGSLIGQKLAINEFVA
                     YLNFSPYLQTGGTLDAKTVAIISFALCGFANFGSIGVVVGAFSAVAPHRAPEIAQLGL
                     RALAAATLSNLMSATIAGFFIGLA"
     gene            complement(69447..70535)
                     /locus_tag="RHX21_000438"
     CDS             complement(69447..70535)
                     /locus_tag="RHX21_000438"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDV1985677.1"
                     /translation="MNDREKQILKILRRNPLIQQNEIADILQISRSRVAAHIMDLMRK
                     GLIKGKGYILTEQDYCVVVGAINMDIRGMADIRYPQAASHPGSVHCSAGGVGRNIAHN
                     LALLGRDVHLISAIGNDFYGETLLEETRRAGVNVSNCIRLHGHSTATYLAIANKQEET
                     ILAINDTHILQQLTPQLLNTSRDLIRHAGVVLADCNLTPEALEWVFTIADEIPMFVDT
                     VSEFKANKVKNWYSRIHTLKPTQNELEILWGQPIKDDNDRIRAVNSLHQQGVKRIFVY
                     LKDESVFCSDKDGEQFLLTAPAHTTVDSFGADDGFMAGLVYSFLEGYSFRDSARFAVA
                     CAAISRASGSLNNPTLSADNALSLVPMV"
     gene            complement(70539..71396)
                     /gene="nfo"
                     /locus_tag="RHX21_000439"
     CDS             complement(70539..71396)
                     /gene="nfo"
                     /locus_tag="RHX21_000439"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HDV1985678.1"
                     /translation="MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPL
                     TTQTIDEFKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLG
                     LSLLNFHPGSHLMQISEEDCLARIAESINIALDKTQGVTAVIENTAGQGSNLGFKFEH
                     LAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTPAECEKTFADFARIVGFKYLRGMHLN
                     DAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLK
                     AQQTEKAVA"
     gene            complement(71470..72519)
                     /locus_tag="RHX21_000440"
     CDS             complement(71470..72519)
                     /locus_tag="RHX21_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HDV1985679.1"
                     /translation="MTNITLQKQHRTLWHFIPGLALSAVITGVALWGGSIPAVAGAGF
                     SALTLAILLGMVLGNTIYPHIWKSCDGGVLFAKQYLLRLGIILYGFRLTFSQIADVGI
                     SGIIIDVLTLSSTFLLACFLGQKVFGLDKHTSWLIGAGSSICGAAAVLATEPVVKAEA
                     SKVTVAVATVVIFGTVAIFLYPAIYPLMSQWFSPETFGIYIGSTVHEVAQVVAAGHAI
                     SPDAENAAVISKMLRVMMLAPFLILLAARVKQLSGANSGEKSKITIPWFAILFIVVAI
                     FNSFHLLPQSVVNMLVTLDTFLLAMAMAALGLTTHVSALKKAGAKPLLMALVLFAWLI
                     VGGGAINYVIQSVIA"
     gene            72618..73499
                     /locus_tag="RHX21_000441"
     CDS             72618..73499
                     /locus_tag="RHX21_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV1985680.1"
                     /translation="MHITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQ
                     LGVQLFDRVGKRLVVNEHGRLLYPRALALLEQAVEIEQLFREDNGAIRIYASSTIGNY
                     ILPAVIARYRHDYPQLPIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLE
                     DELVVFAAPTSPLARGPVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMEL
                     GNSEAIKHAVRHGLGISCLSRRVIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLS
                     NALRRFLDYCDPANVPR"
     gene            73704..75173
                     /gene="lysP"
                     /locus_tag="RHX21_000442"
     CDS             73704..75173
                     /gene="lysP"
                     /locus_tag="RHX21_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine-specific permease"
                     /protein_id="HDV1985681.1"
                     /translation="MVSETKTTEAPGLRRELKARHLTMIAIGGSIGTGLFVASGATIS
                     QAGPGGALLSYMLIGLMVYFLMTSLGELAAYMPVSGSFATYGQNYVEEGFGFALGWNY
                     WYNWAVTIAVDLVAAQLVMSWWFPDTPGWIWSALFLGVIFLLNYISVRGFGEAEYWFS
                     LIKVTTVIVFIIVGVLMIIGIFKGAQPAGWSNWTIGEAPFAGGFAAMIGVAMIVGFSF
                     QGTELIGIAAGESEDPAKNIPRAVRQVFWRILLFYVFAILIISLIIPYTDPSLLRNDV
                     KDISVSPFTLVFQHAGLLSAAAVMNAVILTAVLSAGNSGMYASTRMLYTLACDGKAPR
                     IFAKLSRGGVPRNALYATTVIAGLCFLTSMFGNQTVYLWLLNTSGMTGFIAWLGIAIS
                     HYRFRRGYVLQGHDINDLPYRSGFFPLGPIFAFILCLIITLGQNYEAFLKDTIDWGGV
                     AATYIGIPLFLIIWFGYKLIKGTHFVRYSEMKFPQNDKK"
     gene            75466..77457
                     /gene="cirA"
                     /locus_tag="RHX21_000443"
                     /pseudo
     CDS             75466..77457
                     /gene="cirA"
                     /locus_tag="RHX21_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416660.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="catecholate siderophore receptor CirA"
     gene            complement(77489..78325)
                     /gene="yeiG"
                     /locus_tag="RHX21_000444"
     CDS             complement(77489..78325)
                     /gene="yeiG"
                     /locus_tag="RHX21_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="HDV1985682.1"
                     /translation="MEMLEEHRCFEGWQQRWRHDSSTLNCPMTFSIFLPPPRDHTPPP
                     VLYWLSGLTCNDENFTTKAGAQRVAAELGIVLVMPDTSPRGEQVANDDGYDLGQGAGF
                     YLNATQPPWATHYRMYDYLRDELPALVQSQFNVSDRCAISGHSMGGHGALIMALKNPG
                     KYTSVSAFAPIVNPCSVPWGIKAFSSYLGEDKNAWLEWDSCALMYASNAQDAIPTLID
                     QGDNDQFLADQLQPAVLAEAARQKAWPMTLRIQPGYDHSYYFIASFIEDHLRFHAQYL
                     LK"
     gene            78583..79251
                     /gene="folE"
                     /locus_tag="RHX21_000445"
     CDS             78583..79251
                     /gene="folE"
                     /locus_tag="RHX21_000445"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HDV1985683.1"
                     /translation="MPSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKSLIAGHM
                     TEIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMKVDEMVTV
                     RDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQIL
                     IALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAV
                     RHHN"
     gene            79268..80425
                     /locus_tag="RHX21_000446"
     CDS             79268..80425
                     /locus_tag="RHX21_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF418 family protein"
                     /protein_id="HDV1985684.1"
                     /translation="MERNVTLDFVRGVAILGILLLNISAFGLPKAAYLNPAWYGAITP
                     QDAWTWAFLDLIGQVKFLTLFALLFGAGLQMLLPRGRRWIQSRLTLLVLLGFIHGLLF
                     WDGDILLAYGLVGLICWRLVRDAPSVKSLFNTGVMLYLVGLGVLLLLGLISDSQTSRA
                     WTPDASAILYEKYWKLHGGVDAISNRADGVGNSLLALGAQYGWQLAGMMLIGAALMRS
                     GWLKGQFSLRHYRRTGFVLVAIGVTINLPAIALQWQLDWAYRWCAFLLQMPRELSAPF
                     QAIGYASLFYGFWPQLSRFKLVLAIACVGRMALTNYLLQTLICTTLFYHLGLFMHFDR
                     LELLAFVIPVWLANILFSVIWLRYFRQGPVEWLWRQLTLRAAGTAISKTSR"
     gene            80567..81607
                     /gene="galS"
                     /locus_tag="RHX21_000447"
     CDS             80567..81607
                     /gene="galS"
                     /locus_tag="RHX21_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708050.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator GalS"
                     /protein_id="HDV1985685.1"
                     /translation="MITIRDVARQAGVSVATVSRVLNNSTLVSADTREAVMKAVSELD
                     YRPNANAQALATQVSDTIGVVVMDVSDAFFGALVKAVDLVAQQHQKYVLIGNSYHEAE
                     KERHAIEVLIRQRCNALIVHSKALSDDELAQFMDNIPGMVLINRVVPGYAHRCVCLDN
                     LSGARMATRMLLNNGHQRIGYLSSSHGIEDDAMRKAGWMSALKEQDIIPPESWIGTGT
                     PDMPGGEAAMVELLGRNLQLTAVFAYNDNMAAGALTALKDNGIAIPLHLSIIGFDDIP
                     IARYTDPQLTTVRYPIASMAKLATELALQGAAGNIDPRASHCFMPTLVRRHSVATRQN
                     AATITNSTNQAM"
     gene            81887..82885
                     /gene="mglB"
                     /locus_tag="RHX21_000448"
     CDS             81887..82885
                     /gene="mglB"
                     /locus_tag="RHX21_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/glucose ABC transporter
                     substrate-binding protein MglB"
                     /protein_id="HDV1985686.1"
                     /translation="MNKKVLTLSAVMASMLFGAAAHAADTRIGVTIYKYDDNFMSVVR
                     KAIEQDAKAAPDVQLLMNDSQNDQSKQNDQIDVLLAKGVKALAINLVDPAAAGTVIEK
                     ARGQNVPVVFFNKEPSRKALDSYDKAYYVGTDSKESGIIQGDLIAKHWAANQGWDLNK
                     DGQIQFVLLKGEPGHPDAEARTTYVIKELNDKGIKTEQLQLDTAMWDTAQAKDKMDAW
                     LSGPNANKIEVVIANNDAMAMGAVEALKAHNKSSIPVFGVDALPEALALVKSGALAGT
                     VLNDANNQAKATFDLAKNLADGKGAADGTNWKIDNKVVRVPYVGVDKDNLAEFSKK"
     gene            82946..84466
                     /gene="mglA"
                     /locus_tag="RHX21_000449"
     CDS             82946..84466
                     /gene="mglA"
                     /locus_tag="RHX21_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020883197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/methyl galactoside ABC transporter
                     ATP-binding protein MglA"
                     /protein_id="HDV1985687.1"
                     /translation="MVSSTTPSSGEYLLEMSGINKSFPGVKALDNVNLKVRPHSIHAL
                     MGENGAGKSTLLKCLFGIYQKDSGTILFQGKEIDFHSAKEALENGISMVHQELNLVLQ
                     RSVMDNMWLGRYPTKGMFVDQDKMYRETKAIFDELDIDIDPRARVGTLSVSQMQMIEI
                     AKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDE
                     VTVLRDGQWIATEPLAGLTMDKIIAMMVGRSLNQRFPDKENKPGEVILEVRNLTSLRQ
                     PSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKQINNHNANE
                     AINHGFALVTEERRSTGIYAYLDIGFNSLISNIRNYKNKVGLLDNSRMKSDTQWVIDS
                     MRVKTPGHRTQIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIA
                     ELAKKGKGIIIISSEMPELLGITDRILVMSNGLVSGIVDTKTTTQNEILRLASLHL"
     gene            84482..85492
                     /gene="mglC"
                     /locus_tag="RHX21_000450"
     CDS             84482..85492
                     /gene="mglC"
                     /locus_tag="RHX21_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/methyl galactoside ABC transporter
                     permease MglC"
                     /protein_id="HDV1985688.1"
                     /translation="MSALNKKSFLTYLKEGGIYVVLLVLLAIIIFQDPTFLSLLNLSN
                     ILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAAVVAATLLQSMDNANKVFPEMAT
                     MPIALVILIVCAIGAVIGLINGLIIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASP
                     ISGFDSGFSTFAQGFVALGSFRLSYITFYALIAVAFVWVLWNKTRFGKNIFAIGGNPE
                     AAKVSGVNVGLNLLMIYALSGVFYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGG
                     VSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAIIIFAVALDSLKYAR
                     KK"
     gene            complement(85563..86798)
                     /gene="preA"
                     /locus_tag="RHX21_000451"
     CDS             complement(85563..86798)
                     /gene="preA"
                     /locus_tag="RHX21_000451"
                     /EC_number="1.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416652.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent dihydropyrimidine dehydrogenase
                     subunit PreA"
                     /protein_id="HDV1985689.1"
                     /translation="MLTKDLSITFCGVKFPNPFCLSSSPVGNCYEMCAKAYDTGWGGV
                     VFKTIGFFIANEVSPRFDHLVKEDTGFIGFKNMEQIAEHPLEENLAALRQLKEDYPDK
                     VLIASIMGENEQQWEELARLVQEAGADMIECNFSCPQMTSHAMGSDVGQSPELVEKYC
                     RAVKRGSTLPMLAKMTPNIGDMCEVALAAKRGGADGIAAINTVKSITNIDLNQKIGMP
                     IVNGKSSISGYSGKAVKPIALRFIQQMRTHPELRDFPISGIGGIETWEDAAEFLLLGA
                     ATLQVTTGIMQYGYRIVEDMASGLSHYLADQGFDSLQEMVGLANNNIVPAEDLDRSYI
                     VYPRINLDKCVGCGRCYISCYDGGHQAMEWSEKTRTPHCNTEKCVGCLLCGHVCPVGC
                     IELGEVKFKKGEKEHPVTL"
     gene            complement(86792..88030)
                     /gene="preT"
                     /locus_tag="RHX21_000452"
     CDS             complement(86792..88030)
                     /gene="preT"
                     /locus_tag="RHX21_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent dihydropyrimidine dehydrogenase
                     subunit PreT"
                     /protein_id="HDV1985690.1"
                     /translation="MPQQNYLDELTPAFTPLLAIKEASRCLLCHDAPCSQACPAQTDP
                     GKFIRSIYFRNFKGAAETIRENNALGAVCARVCPTEKLCQSGCTRAGVDTPIDIGRLQ
                     RFVTDFEQQTGMEIYQPGTKTLGKVAIIGAGPAGLQASVTLTNQGYDVTIYEKEAHPG
                     GWLRNGIPQFRLPQSVLDAEIARIEKMGVTIKCNNEVGNTLTLEQLKAENRAVLVTVG
                     LSSGSGLSLFEHSDVEIAVDFLQRARQAQGDISIPQSALIIGGGDVAMDVASTLKVLG
                     CQAVTCVAREELDEFPASEKEFASARELGVSIIDGFTPVAVEGNKVTFKHVRLPGELT
                     MAADKIILAVGQHARLDAFAELEPQRNTIKTQNYQTRDPQVFAAGDIVEGDKTVVYAV
                     KTGKEAAEAIHHYLEGACSC"
BASE COUNT        21958 a        22473 c        22822 g        21069 t
ORIGIN      
        1 catcaggcaa cggctgtcgg atgcggcgta aacgccttat ccgacctacg gttctacccc
       61 tgcgtaggcc tgataagacg cgccagcgtc gcatcaggca agaccgtatt aattcggcgt
      121 gtagcccatt accacgccac ttaagccaga aagttgcttc aactcaccca gcgatccttt
      181 cagcttatct ttcgaggcat ctggcccaac cagaatacgg gtaattttac cctgcactgg
      241 cgtggatggc gacgtataaa cccgataacc ggcaccgcgc agcttaccga caatctcatt
      301 cactttatcg gcatttttca gcgcgcccag ttgcacaaca taggctttac ccgttggcgc
      361 tgctttttct tccacgaccg gcttcggttc tggcttcggc gcaggtggtg cttcaacctt
      421 cggcttaggc ggctccaccg gtttcggctt cggtgggacg accggtgcag gttccggttc
      481 aaactcggtg ttattggctg caatagtggc cggatcgagc gacggtgctg cggcatcacc
      541 tgcccgcacc tcttccgctg cgccttccgg cggttgcgtc ggcaacgcct gggtggcggc
      601 tggcatcata tcaggctcat cgcgatcgcc cgcttttggc accagcggga tagccgcaaa
      661 ctcatcctga taatgttttt tctgcccgtc cagcagccct ggaagtacaa tcacccccag
      721 cgccaccagc acgatcgtgc ccactaaccg attctgaaac ttacttgcca ccgcttctcc
      781 tcgcgtcaat cacttccatg acatgtgcga ccgtgtggaa cgaaccacac accagcacgg
      841 tgtcttccgc tttagcgtcc gccattgcgg catcccatgc ctgcgcaacg ctatcaaatg
      901 atttgccgtt acccaaatgc tcaagcagtt gttctgccgt ggcaccgcgc ggcccttcca
      961 gtggcgcaca ataccagtca tcaaccacgc ttttcaacca ggccagagtt ccggcaatat
     1021 ctttatcatg tagcataccg ataaccgcca gcacgcgccc gtttttcggt agcgttttca
     1081 tacgcccggt gagatattcc gccgcatgtg gattatgcgc gacatcaaaa ataacgcgtg
     1141 gcgactcgct cacaatctgg aaacgtcccg gcaaaattgc gctggcaatc ccgtcgcgaa
     1201 tggcattttc actgacctcc agcccgctgg cacgcagtgc cgccagcgcc gttgcggcat
     1261 tcggttgcgg gacaagcggc aacggcaggt tttccagcgt gccgtgagca tcgctaaacg
     1321 cccagtcatg atcggtgacg gaatagttcc actcaacgcc ccgacgttgt aacagtgcac
     1381 ctttttcctg cgctacatca gcaatggtag aaggcatttc cggctcaccg acaattgccg
     1441 gtttttcgct gcgaaagatg cctgctttct cgcgaccaat actttcgcga tctggcccca
     1501 gccagtcggt atgatccagc gcaatactgg ttactaccgc gacatcggcg tcgacaatat
     1561 tggttgcgtc cagacgaccg cccagcccta cttccagaat caccacgtca agttgtgcct
     1621 gtttaaacag ccacaacgcc gacagcgtac cgtactcgaa ataggtcagg gaaatatcac
     1681 cgcgtgccga ttcaatctcc gcaaaagagg cggtgtgggc cgattccggc aattccttac
     1741 cctgcacacg tacgcgctcg gtataacgca ccagatgcgg cgaactgtag acgcccactt
     1801 tgtaccctgc cgccatcaga atcgactcca gcgtacggca ggtggtgcct ttgccattcg
     1861 tacccgcaac ggtaaataca aatggcgctg gtttcaggac gccaagacgc gccgcgacct
     1921 ggctcacgcg ctcaaggccg agatcgatag ttttactgtg caggttttcc agataagaaa
     1981 gccacgaagc cagaggcgac gcggcttgag gagtgcgttt gataatcatg gtatccgctg
     2041 attcgttacg gtgagaatag caaaagggca gagccagtgg ccctgccctt atcagttatc
     2101 aggcctcagg ttcctgatcc ggtaccgggg gtaccactac gccttcacgc ggcgcttcag
     2161 gattcggcgc tggcagattc atcaacttcg ccagaatgct cgccagtttc aggcgcattt
     2221 ccggacgacg gacgatcatg tcgatcgcgc ctttctcgat caggaattca ctgcgctgga
     2281 atcctggcgg cagtttttcg cgaacggtct gttcgataac acgcggaccg gcaaagccga
     2341 ttaacgcttt cggttcagcg atgttgagat cgcccagcat ggcgaaactt gcagaaacac
     2401 cgcccatcgt cgggtcggtc agcacggaga tgtacggcaa gccgcgctcc tgcatttttg
     2461 ccagtgccgc agaagttttc gccatctgca tcagcgacat cagtgcttcc tgcatacgtg
     2521 cgccaccaga ggcggagaag cagatcagcg ggcagttatc ttccagcgcc tgctcaacgg
     2581 cacgcacgaa acgtgcaccc acaacagacc ccattgaacc gcccataaag gcgaactcga
     2641 atgccgcagc gacaaccggc attccataca gagtgccttt catcaccacc agcgcatctt
     2701 tttcgccggt ttctttctgc gcagatgcca gacggtcttt atacttcttg gagtcacgaa
     2761 acttcagcac atctttcggc tcaagctcgc tacccagctc cacaaggctt ccttcatcta
     2821 acaggctatg caggcgatta cgcgctgtca tacgcatgtg atggtcacac ttcggacaga
     2881 cctcaagatt acgttccagc tcagcgcggt ataaaacctg accgcagcta tcacacttag
     2941 tccacacccc ttcaggaatg ctcgccttgc gggtgggagt aatgttgctt ttaattcgtt
     3001 caatccagct cattagggac ctttctgtct gaacctggtt cgatgccagt tttatctttg
     3061 gggacgcata atgccatttt tgcccccaac agaccatgaa tgttgcacat taaaacataa
     3121 cagcccgaaa ctttggataa aaaagtggtc gaaccgcgga gttacttttt attttgcggc
     3181 gcgtgccgca gcgcgtttgt gacggattat ttcgatgacg cccggcaaaa tagaaaccac
     3241 aataatcccg acgatcagca gcttaaggtt atcctgaacc atcgggattg taccgaagaa
     3301 atagcctgcg taggtaaaaa gcagtaccca caacagtgcg ccgatcacgt tataagcggc
     3361 gaaatgacgg tacgacatgt ggcccattcc cgcaacaaac ggggcgaacg ttctgacgat
     3421 cggcacaaaa cgggcgagaa taatcgtttt gccgccatgt ttctcataaa actgatgggt
     3481 tttgtcgaga taactgcgac ggaaaatttt cgaattggga ttactgaata acttttcacc
     3541 gaacaaccgc ccgatagtgt aattgaccgc gtcacccaca atcgcggcga tcagcatcag
     3601 caccaccatc atatggacgt tgagatcgtt ggtttccagt gatgccaacg ctccggcaac
     3661 aaacagcaat gaatcacccg gtaaaaacgg cgttaccacc agaccggttt cacagaacaa
     3721 aattaagaac aaaatggcat aaacccagac gccgtactcc gcgaccagct ctgccagatg
     3781 cacgtcaatg tgcaggataa aatcgatgag gaaataaatc aggtccatat ttgcctatgc
     3841 cttgtactcg tcatctttca ggctgtaact acgttggcta cagcctgaaa tgttccgagc
     3901 attattctcg ttagtccgcc agaaatagcg ggcccattgg cggttttgga agatcatacc
     3961 ggtcagggta atccaccgcg accagataca gcccttccgc ttttgccgtt gctgccgcca
     4021 gcgttctgtc ctttgccgcc agcaactctg ctatccagct ctccggctgg ttgtgggcac
     4081 cgacttccat caggctgccg acaatattcc tgaccatatg atgtacaaag gcattcgctt
     4141 tgatatctac caccacataa ggaccgtgac gcgtgacatt aatatgcata acgttgcgcc
     4201 acggggttcg ggactggcac tgcaccgcac ggaacgaggt gaaatcattc tcgcccagca
     4261 agcattgcgc agcccgatgc atccgttcag cgtccagcgg ttcgtaaaaa tgggttaccc
     4321 ctttactcag taccgccggg cgcagccgat gattgtagat gatatagcga taacggcgag
     4381 ccgtggcgct aaatcgggca tgaaaatcat caggtacagc tttaacccaa cgcacggcga
     4441 tgtcaccagg taaattcgca tttacgccca acgtccacgc agcgtctttg cgctgcgcgg
     4501 ttgtttcgaa atgcaccacc tgcccggtac cgtgtacccc tgcgtcagta cgcccggcgc
     4561 agaagacggt gatgggttcg ttcgccacct gggagagcgc cttttccagc ttctcctgca
     4621 cactgcgaac ttcgttctgc cgttgccagc cgtaatactt actgccgtcg tactcaatgc
     4681 ccagcgcaat tttataaact ggcggttgtt gctggtcgga cattagtaca gatactcctg
     4741 caccagtttc tcggcgattt ttactgccat cagcgcgccg ccaaagcgaa cgttatcggc
     4801 caccgaccag aactggactt gctccggcat accgtagtca ttacgcacgc agccaacaga
     4861 aagatgcggc gtacccgaag catcccctac ctgagttggg aattcgttct cttcagagag
     4921 cacaatatct tcgccttgaa caaacgcatc acgcgcttct tctgctgcca gtggacgcag
     4981 agcttcaaag ttgaccatct gggcatgacc gtagaatacc ggtgcctgga cgacgcttgc
     5041 cgaaatcatc agtccttcgt cctgcaggat tttgcgtact tcgtcaacga tacgacgttc
     5101 ttcacgcacg ctaccttcgc tatccggcag taacggcagc atgttgaacg ccagctgacg
     5161 cccgaagaaa tcttcttcgt caatcggaat gccgttgagc aatttagcac tctgccccgc
     5221 taacgcatcg accgcttttt tgccctgggc ggaggctgaa atcaggctgg taacgctgat
     5281 acgtgataaa ccgccctgat cgattaacgg tttcagtgcc gccagcagct ggctggtcag
     5341 actgtccggt acggcgatga cattccggtt gcggtaatcg gtcagtacaa acgggtttac
     5401 ttccggcacc accagcggta cgtcgggttc gagagcaaac aatccgctgc tgtcgatcac
     5461 caggcaacct gagttggtcg cttcttcaac ccaggctgcg gtagcttctt tgcctgcgac
     5521 aaaaaatgcc agctgcgcct gcgtccagtc gaattcagca gcatcctgca cggtgattgt
     5581 cttaccacca aagcgcagtt gttcgcctgc gctttcgtta cgtgccagtg cataaatttc
     5641 cccaaccggg aactgacgtt cagccagcgt ttcaagcagg gcttcgccca cagcgccagt
     5701 tgcgcccagg acggcaatgt tccagccttc agacatggtg gtttactcca gaaatagcaa
     5761 agctccctgc caatgttaca gcagagagca tgaagaagag attaacgtgc cggatgatga
     5821 acggcgttaa aacccagttt acacagcaat gatgccgcac tggcgtcatc acaaattaca
     5881 tacagagatg accattcacg gcgctcaaga tagtttttgc gcagtttatc gaactcaccc
     5941 ggtatcccgg cgactttacg cagcggtgcg tcatcgcggc gcacatcata caccaaatgc
     6001 accagccttt tcagcgttgg ttgatcgagc gggccatgca gcgtaatgcg accaaactct
     6061 ggcgcgggca gtaatgtatc cagcgcaatg tgctgttcat gcccaataaa cttgctatag
     6121 gcttcaaaca cttgcgtagt accgcgtgct ttaccttcca gggtatagcc tgcaatatgc
     6181 ggcgtgccga tatccacttt tgtcagcaac tccacgttaa gttccggttc gccttcccag
     6241 acatccagca ctacgcttaa cttctggcct tcattcaggc aggtcagcag cgcggtatta
     6301 tcgacgactg cgccacggca ggcgttaatc agaatcgctc cgggcttcag gttacggatc
     6361 agtttttcat ccgccagatg cagcgttttg tacggcccgt ctttgaagag tggcgtatgg
     6421 aaagtcagaa tatccgcatg ctgaactaat tcatccagcg agcggaaatc accctcatcc
     6481 ccacggtcag cgcgaggcgg atcgcaaagc aaggttttaa tccctaacgc ttccagtcgc
     6541 gcctgcaatc gacgtccaac gttaccaacg cccacgatcc ccaccgtacg gtcgtgcagt
     6601 gaaaatccat cgcgttcggc aagcatcagt agtgaggaga gaacatattc caccaccgca
     6661 atcgcattac agccaggtgc agcggaaaaa ccaattcccg ccttctttaa ccatgcttca
     6721 tcgacatggt ctgtccccgc agtggcagtg ccaacaaatt taatgggttt tcctgccagc
     6781 aaagattcat tcactttcgt gaccgaacgc accatcagcg catccgcgtc tgccagttga
     6841 gcgacgggga ttggacgccc gggaaccgcg atcacctcac ccaaacggct aaataagtcg
     6901 cgggcataag gcatattttc atcaacaagg atttttaacc ctttttcagt ctctgacaat
     6961 ctaaggctcc tttattaaca aacgcccatt tgcaaactgc tgtttaatct aaaaaaaaca
     7021 ttcataatca tacagataac aacataacca tttagacggg caatactgaa aaattgttat
     7081 tcagtatcac cctttaagcc gtttcaggct atataaaatt aatcccccgt ggacactgcg
     7141 tggacactca cgccaccttt cagcggatta agggccaccg catcctgcag gtaatccggt
     7201 gcaaaatgtg catatgccat tgtttgctga atggttgcgt gaccaagaat cttctgaagc
     7261 gcaataatgt ttcctccgtt catcacaaaa tggctggcga acgtatgccg cagcacatgt
     7321 gcagcctggc cttttggtaa atcgggctta actcttttca gcgccaggca gaattcccgg
     7381 tacttcacct caaacaagct gcctgtttct ctggttttga tcgcctcaca aactgcctgc
     7441 gaaattggca ctgttctctt ccggccattt ttggtttcaa gaaacgttac acggttatga
     7501 actatctgtt caccacgaag cttacaagct tcactccagc gcgcccctgt gcttaaacac
     7561 aaaagcgcaa cacgccagta gtcgccctcc agtgtatcga gcaatagcgc tacttccttc
     7621 tgggacagga aagccatttc tcgcggggat acataaagaa tggagatccc ccttaccgga
     7681 tgttctgcat cccaaaggcc tattcttttc agaacagtaa acatgccgga tagtcggttc
     7741 atgtacctgt tagcagatga cggtttcaat ccagcagcta tcttttgaga acgccacgcg
     7801 ataattttca gcttatcaag atccacagcc tgcatatcag cgccaagctc actgattatg
     7861 ttgcgcagtt gttttcggtc ttcttccgcc ttacgcctgt gttgaccgtg atacatccac
     7921 cacaactcaa gcaaatcatt tagcgttcgg cgatcacggt agccctgtat atattcccgc
     7981 ttttcagcgt tcgccatgat gtagcgttca gtggccaccg ctaccgattt tttgtcaaat
     8041 accttacgca cgcgctttcc cttgcgtccg ttcggcctga tgtccagcaa ataacgacca
     8101 tcttcgagct tcttaattga cattgcgaag ccctccaatg aaccgctcta caatttctcc
     8161 agcctctttc cagcaataat cagaccagaa aaagagcagg tctaaccagt tttctggcct
     8221 tagcggggtg atttttggtt tgtttcggtt gaaacctgat cgccctccga atcgaagaaa
     8281 ccatcaagag agagaggcgg agcaatctgc cccgtcgcag cattagtttg attaaacatc
     8341 acccaatccg aatacttccg aaaacgagga tgattcaaaa tcaggagtaa cgtttctcca
     8401 ggtatcattc ttcccaatat ttcataattt ttgagattgt tttgagatac ccctgtcacc
     8461 tcttccatct ctctacgtga caatccctct gcctctcgaa tcaggcgaag tttttctcca
     8521 aggcttgatt tatggatcat atgtgatcta aactccacac tattgggtta tatgtaatac
     8581 aaaacattca aatagccaaa ataagcctat ataagccatt ttgggccatt tggacgaatt
     8641 aaggagatta ccacaatgag cgaatcagag cttgaggggt tcattcaggt agcaccatat
     8701 ccacttgaag cggtgccata tcaactattt gccaagatga ttggtcgcaa agaatcaacc
     8761 gtcagaacca tgattgacgc tgcaaagtta ccaacgattg actttgtgaa accaggttca
     8821 gtgaagacgc gagcatcaga aaactgggta tatttgccag catttaacgc aggtatgcgc
     8881 aaagcgtttt ttgatcagcc gaaagaacgc cgcgatgcat ggttgttgtg gctggggctt
     8941 taatcataaa tgaccagcaa tatcaccagc gccattttga cccttgtttt tattgagata
     9001 ggcgtaatag cgatctattt gtttcgcaag ttaacgggac atgaagaacg ctttattgaa
     9061 ctcagcattg aatatatcgc cgcttatacc aaaggacttt tcccggcagc tattggggcg
     9121 atgtttatag cgtttgttat ctggtttatc gggtgagaaa cctgacaacc cacaactact
     9181 gcaatgaggg taattatgtg tggcatggac aaattggacc ttatgttaat tgtaatacta
     9241 tcaattaact tcggttacct cttaagcggc gcaattctca tgtgcggagg caaacgaaaa
     9301 tgaaccagca gtccgcaaaa cgtgaaaaca atgcgatgcg atttaatcgc aaatattttg
     9361 agttcggcct ctatgccgga ataattaaat ctgtacagag tctttaacat gaaacagcaa
     9421 cgtaattcac gctttcgcaa tggtgcagaa cgccacgcta accgttttgc taccagtgca
     9481 tcacgcagca acatccgcta cagcctgagt gatacacacg caacgccgga tggctaccca
     9541 gtaaaacaaa tcggcgagca cacctggctg attgagaaag ctggaatcgt gctccacaaa
     9601 tgcccacgca atccgtttac cggaaaccgc atttttgctc taagcagtgg cgacaatcag
     9661 ttcgggcagg atttcacatt atacgaagca cttcgcacgg ttgatcgtct gcttcgcggg
     9721 caaagtttta ttaaacaggc tgatttataa caggtgcttt atgaccaaag accatgcaca
     9781 aggtgtattt atccgtttta ttgattttcg cggtgaactg ttattacgtg catccgctat
     9841 tgacggagtg actccggcgg gtaaaaacgg agccgacgaa gccacttacg tttatctgaa
     9901 cggcacgcga ctgcttgtgg aacttccgta ccagaccgta cgagaaatca ttagcgaagc
     9961 tgaaaaggca cgtcaggtta atggcgatga agcctatatc gaaattattt gtatggattc
    10021 agaagctgaa attcagaaag cagattaaag ggcgttgcga tgggcaaaga atataaaact
    10081 ctcattaaca aagcacttga acgattttat tttcgcttaa gtgcatcagg cgctcatact
    10141 gaacgtgcag cccgtgactc attgaccagg gcaatccgga gtttgtatga cgttgctttt
    10201 tacgctgatg atctggatgc acttaacgaa ctttccgagc tgatctgtgc cgcagaatgc
    10261 ggggaacaca ttgaaccgta taagctgggg aatatcgcat gagtatattt atctcatggc
    10321 ttgttctgat tatttcggtg gcctgcgcca ttgggattat gcgaattatt aattcagtga
    10381 aaaagatcga gcgttttttc tctgatgaat aacgatacaa ataaaacatc aaattaaata
    10441 agaaaacgtg aaaaccatcc gtattaacgg aggtattcgc acacgcaaat aacggagata
    10501 caaaaatgca cgcaaaagaa gaaggtatca tcagagcact gaaagaaatt tcaaagatgg
    10561 aaagcgaagt agcgaaaaaa gccgtggcca atgctcacat ggacgtcgca acccacacaa
    10621 tgatagtcgc aaaagtcacg gcagaggctg ccaaaatcat cgaagaacag ggtgtggaac
    10681 ttgcgcttct caaaactaaa ccagtcaccg gactggattt atctgacacc ggacgcctta
    10741 tttacactat tggctcggag ccacagcgat acaccattat cgccggatta cagaacaaat
    10801 acctgatcac tcctcacccc ataagggaat cagcgcttct gacaaatctc cgcctgatag
    10861 agcgctctca agttgcattc attgatgacg cccgacacac cgtatttaac gcatagggtt
    10921 actggacaaa gggggtgcaa tggcaattaa gcattttccc gtcgttcgct ttacctccag
    10981 agggcgcgaa tacgaggtcg acgaacgcct gattaccact atcgacaaac atcgttcgga
    11041 aaaggatgca caccacatct acctcactga cggtacttac ttctgcgcca ccaacgtggc
    11101 gcgggtgaat cttatccgac aggtacagga gccacgcaga tgaccattct ggactacatc
    11161 gctactcatc cgggttgtag cggcggagag atcgccgcag cactgaatac tccaaccaca
    11221 gccattaatg ctgagttacg ccaactttgg cgcggcggct tagtcatcag aacaaaccgc
    11281 agcacaggtg gtcgcgctcg caaaactgga ggccaggctt cttaccacgt aaacccgatg
    11341 ccgttcgggt gtagcaatcc acttactcac atgtttaacc agctactgaa ggaagccaga
    11401 acatgagcac catcaaccac cagaagctac gcgaactggc atttgccctg caacgaatgg
    11461 caacgcctca aaaattactg gcatttcgcg caatgctctc gccgtctgct gtgctggcac
    11521 tgctggatga gctggagcac gccagaacca cggctcctgc cattcgcctg acactccatc
    11581 atgaaatcgc tgatttctgc gcgacgttgg aggcaccagg cgaaccggaa acgccggaag
    11641 caatacagca agagctgctg caacgcattg acaaggtttt tgattttttt ctgaaccagt
    11701 aagaaaccag aacatgcaca cacaaaaaaa ccgcttgcca tgccgcaatc agtcaggtta
    11761 catttccgct gcacctcata aaacgggtgc cgggattctc aacccgatac agagcaaagc
    11821 gcataaccgc gccagcggtt tttttgtgcg tactgtattg ccacgtcttt ttcgcgtcag
    11881 aattatggcg gggcgtacgg ggccgacttc ggtcgggccg gattctttgc tctccggtgt
    11941 tgagaaccct gtacgtctcg ccaccccgag attctcaact ctggatggtg agctatttct
    12001 atcaccgagc aaagaggcca caccatggca aaccgcaaac aacagcgcgc atacgctgcg
    12061 cgtcgtcaca tccagactga aatcaaccgt agacttttcc gcgcatcacg cgtcgcgcaa
    12121 atcatgcaca tcaatatgct gcatgagcgc agccacgcgc tatcgaacat ctattccgcc
    12181 tctgttttca gctatctggc ggatgatctg cgcgagctgc aacaactctt ccagtagcaa
    12241 aacaaactcc attaattcct gttccgggcc tttcctgcac cttgcggcgg gaggccttcg
    12301 cacatctgta gtaaagagaa ttgcagcatg attgacgctc atgacttcac aagatgggtg
    12361 cgcacacagg acacccgtct ggctcccgtt cttcagggat tatttgatct ctacatccgt
    12421 ggtcgtgaca acagagcacg caccacaaaa ccagagaatg cagacaccct ttatttcaca
    12481 gtagacgact gctaccgcgt ggacttcaca ccacacgggc tggcgttgca ctgcctgaca
    12541 ccacacggag aatcactgct ggcgtattac gactccccgg cctccgtatt tgcggcaatg
    12601 ctggcgcatc gcactgctgg cgggtgtgcc tcgctgagtg aatacaccgc tgaatttaac
    12661 cgcctttctg ccctcttctc gcaggagtgg cagcgcgtga cgggatacca gccatgagtg
    12721 agtttgcatg gagctggaat gaaccacggc cagccattga tccggccaga tttacggagc
    12781 acaggcagga aactgaaacc gacctgcaac gcgccatccg ttactacctt gaggcggaca
    12841 aaaaggcccg ggaagaacag gaagcgaagg aggaagcctt tttcgcacaa tccgccatgg
    12901 gtaaaaaact catggcatcc cttgaggaag ccggacagcg tgaaaagctg gcacagagca
    12961 tcatcagtaa gcgccgggca acagaacaag acccggtggc ccgtgccttt gccacactga
    13021 aggcgcttcc cgtttatctg cgagaacctc tgagccgcca cctctctttc ctgcgcaaga
    13081 agcaggaagc cgatcgtcag aaaggcaaaa agagctggca ggcggaacgc tatgcacgcg
    13141 gaaccctgcg caaaatattc gaacgtctgg accgcaccga cagccgctgg ctgacaccgg
    13201 gttatcgctc ccttgccgga cgcgaacgcc tggacgattt gctttacctg ccgcagctca
    13261 acaaacacca gatacagacg ctggccacca tgacggcggc gatgttcagc agcaccttcg
    13321 aaaaactctg cgatggcttt ggcgcgactg atggcgaact gaccatggat gtaacgctga
    13381 aggcgtatca gatgctggcc cgcatggcgt tacacctgca cgccatgcct ccacattatg
    13441 acgcactgac aacagacaaa gaccggagga acgaaccgga cacggagctg ctgccgggcg
    13501 caatccttcg cctgacctgt gcggaatggt ggaaacgcaa actgtggctg ttacgttgcg
    13561 agtggagaga agaacaactc cgcgccgcct gtctggtttc cagaaaaaca tcaccctatc
    13621 tgagccagga cgcgttaagc gagtttcgcg cacagcgcga gaaaacacgc gatttcctga
    13681 aaagttttat gctggaaaac gaagacgggt tcacgattga tctcgaaaca gtgtattacg
    13741 cgggagtaag taacccggtt caccgtaagg cagaaatgat ggccaccatg aaggggctgg
    13801 aacttctggc cgaagcccgt ggcgacaaag cggtgtttct gactgtcacc tgcccgtcaa
    13861 aataccacgc cacaacagag aacggtcatc cgaatcccaa atggaacggg gccaccatgc
    13921 gcgactccag cgattacctg gttaacacgt tttttgcggc ggtccgcaag aaactgaacc
    13981 gcgacggcct gcgctggtat ggcatccgca cggtggagcc tcaccatgac ggcaccgtgc
    14041 actggcatat gatggtcttt gctcatccgg aagaaatcga caccattgtg tcccacaccc
    14101 gcgatattgc cattcaggaa gatcgtcacg agctgggtga tgatattacc ccacgcttta
    14161 aggcggagta cgtcgacggc tcaaaaggta cgccaaccag ctacatcgcc acctacatcg
    14221 gaaagaacct ggacagccgc gccgtggatg gcatcgaccc gaaaacgggc aagccacgcg
    14281 ttgaccacga aaccggaaaa tcaatggccg agagcgtgga acgcgccatc ggctgggcgc
    14341 gccttcaccg tgtccgccag ttccagttct ttggtatccc ctcccgtcag gtgtggcgtg
    14401 aactccgccg ccttgccagc cagatggcac gcaacccgga aggcccgcaa cggctgaagg
    14461 atgacgcaat ggatgcggta ctcgctgccg ctgatgccgg atgttttgcc acctacatag
    14521 agaaacaggg cggcgtactt gttccacgca aagactacct gattcgcacc gcctacgacc
    14581 tcgcagatga gctgaacgat tacggcgaac agagtgtaca gatttacggg atctggtcgc
    14641 cgctcatcgg ggaatcctcc cgtgtgtgca cgcatccgga taactggaag ctggtaagac
    14701 gtaaaccgga agcggaagac agcgcccgcg aaaatggttt tgaccttcag ggcggccctg
    14761 ccgccccttg gactcgtggc aataactgtc cccgtgcaca ggaaacggac aacaacggga
    14821 cagaacagcc ggaagaacgg ccagcaccgt ggccgcagct tcctgacggc attgaagtga
    14881 acgaatggat gcgctcactg aaacggcacg aacgccgggc gctgatgcgt tcgcttcgtg
    14941 acaaacaggc aaaaaacagc agtgatgaaa tgcagagctg gacacagagc cgcaaacagc
    15001 agcggccttt gcctgataac cacgaattac tcgctagaga atggcgggag tctgctgaat
    15061 ctctcggcct gcatatcggt gaacaacaaa tgcagcacct gttacggggc ggcagtctgt
    15121 acgttgacgg cagcatcatt gcaccgcagg gatttgaaat tgtacgcaaa ccggataccc
    15181 gcccggacag ccgaatcacg cagctctggc agcgcctgag ccgtaatcac ggtgtaagca
    15241 gcacggagat ccgccataac ccggtcgcca gctatctggc acagctgggg gcatcagacc
    15301 ctgaagccgc cacacgcctg gcatccacac ttcagcagga ccagaacacc atgaaaacac
    15361 ccgttaccgc gctttctgac atgctgcgcg ccatccgcga cgcagagcac gcacagagaa
    15421 tcagtgaaac cactgaacgc gcccgccgca aagcagacct gctgcggggt ggcctgacca
    15481 gtggaaacaa aaaacagaca gaaacgggac tcacgaatcc cgtaaatgag caaaaaacgc
    15541 gcagcgatat atgaagcgcg cacaaaacag gcaaaaacgg gatttcagaa tcccgtaaac
    15601 gattaattaa tcaacataag gaaaagcgac atgaaaattt gtatcgacga cggctccacc
    15661 aacatcaagc tggcatggac tgagaacggc gaacgccgca acgccatcag cccgaacagc
    15721 ttcaagtcgg aatggtctgc gccgttcggt ggtacgcagc ccgcgaacta catgcttgat
    15781 ggcgtgcgct atggttttga tccggtcagc gatcgctttg tccagacgac cgacacgcaa
    15841 taccagtaca gcgatgtgaa tgtcattgcc attcatcacg cgctggtcaa atcaggcatc
    15901 acgccacagg aggtggatgt ggttgtcacc ctgccactga gcgagtattt cgacacaaac
    15961 gcacagccgg acatggctaa catcagccgc aaaaaagcga acgttatgcg cccggtggag
    16021 taccagaacg gcgaagcatt cactatccgt aacgtacggg ttatgcctga atccattccg
    16081 gctggcttta aagcactggc tgacatgagt ccgtttgaat ccctgctgat tgtggatttg
    16141 ggcggaacca cgctggatgt ggcaaaggtt caggggcaac tggcaggtat cagccaggtg
    16201 ttttgcgatc cacacgtagg cgtttccctg atggccgatg ccgtactgtc ggtgatggcc
    16261 actaacggta tgcgtaccag tcaccacatc gccaatacca ttatcgaaca tcgccatgat
    16321 gaagcctggc tgcgccagca catccacaat gacgcgcatt acgacagcct gatggcggtt
    16381 attcgtgaaa aggaagaaac actgaaacaa cgcgtgatcc gcgcgctggc gggtttttcg
    16441 ggttacgggc gggtgatggt tgtcggtggc ggggcggaga ttgtggcacc cgctatccgc
    16501 gaagcctgcg gagttaatgc gactttcatc gcggacgggg tgccacagtt tgctctggtt
    16561 aatgggctgt acgcaatgga caaggagtaa accaatgacg acaccaacca gacggataag
    16621 tttctatctg aagcccgtcg ccgtcaagaa cgaaggcgaa gcatgtgcct ggctggacag
    16681 ccttacacca gaagcccgca aaagcggcca acgcgtggct tttctggccg ggctggcact
    16741 tctgaaaatg aatccagcag aggcttaccg actggctgca tgggctgacg atgaggcgtt
    16801 atcggtgaca caaaccagga cagaacgccc cgtgtcacag ccagtaccaa ccacacagat
    16861 aaccagtcag atggcaggga atatccgggc attatttcct gaatgacgaa tttgacggct
    16921 tttaatttta tcggggtgca ctgtcgcccc gcgcgaggaa aacacgatga aaaaatacga
    16981 atacatgcta atgaaagaag cactgcgggc tggtctggct ccctgtcctg tatccgtaga
    17041 agctgttgtt gggaacacga ttttccgaac gctgcgaaat cgcgtatccg tgaagatgat
    17101 tcaccaacca cccaaatcta ccagcatgat ctatctgccg ctgcccgagg ctatcaaact
    17161 tatgcgttcg ctgaaatttg cgatttggat gcagacacaa ctcaacaaag cggtgcaaaa
    17221 caccttcgtt aagaaactga tgccggagct tgctgccaga tgtgcaaaat gtaccagacc
    17281 cgcacttcaa tttgatctgt cattgattca acaagctacg gaggcagaac tgtaccgcct
    17341 gtcacctctc catgatgctc acacggaagc ctcagaaatg ttccggctca tgtttcaatt
    17401 taattttgcc gttcgacgca cacgcgttca ggtcaatcgc atgatgcagg cgcaggaaga
    17461 gctggcgcaa cacaaaggag gcaaccagtg agcaagattg actatcaggc attacgcgaa
    17521 cgttattcac ctgcgccagt accgaaatgc cctatttgcg gcgaggaaat gtcaattcag
    17581 cgaatatctg gagcacaggt tgtttatgcc tgctccggtt atggtgatga tggagatttc
    17641 aaaattggcc gaactcttgc cgacgaacat tatgaaaaat cacgcgtaac agtgttggat
    17701 gtcggggatc ctgaagtatt ggcgctactt gattggctgg aaaccaaaga caaccgaatc
    17761 gctgaactgg aaaaaatcgc cactgactat gcacttaaat tccagaaagc acaggacgca
    17821 ttaaagtatg ccgctttgct gcatagccgg acggcgcaac aaacaaataa ttttgcagta
    17881 tcgcttccgg acataagcga atatttcatt aatgacgtat ttcagccctt gcgatacgag
    17941 cgggatgttg aaagagccat cataaaggct ggcggaaaag cattgtggca ggagaaacac
    18001 gaggacagaa cgcatcagtc ctgcgatgta aattgtggat ggtttagccc actgacgaca
    18061 gataaaaata acacctgatc cccctcaaac cagggcgata atcgcacatc gcccttctgc
    18121 acaatagtgc acaaatttgc acaatttttt tgaacgactt tttgcccttc cggcccgcgt
    18181 ggcggctgga tccgccaagg atccgtgcgt gcacaaaaaa acacgctttt tctgcgcgca
    18241 ggtgacgggg gaacagcccg cgtttcaggg ggtaaatagt attccctgag cgatgtcgca
    18301 gcgacataac agaatggcca tatttctcac gctgagcgtg aaaaagatgt gagggctttt
    18361 gatttgatgg ggtgaaaggt aaggccgtca aaatcgcact gaggcggtga gaacatgcag
    18421 tcagcgcggt gggattgcgt aagagtctga ccgtcgatga tggtaataaa caggaaagcg
    18481 tcgtgaaatt atctgattga tacaggagct ggagagtcgg ggcataaatt ttttatgccc
    18541 cggcgaagca gcagacaagc gaagcgcgtc aggatgtggg ctgggtgtct aacagtgcgt
    18601 aagggttaaa gcggatcacc tcttcgccaa gccagtcatt gatgtgcttc atggcctcca
    18661 tgacgggcat cagctcgtta attgcgtaaa cccgcgcggc cttctccaca tcaccaaacg
    18721 cacttttttc gcccggcatc gcccccatca gttgcggtgg aacgcggtgc gcagccagca
    18781 catcatcacg ggatgccgcc ttaacattca tgaactcatc ctttgcggtg atctgctgaa
    18841 acggcaaaat ttgcaccccc tctttgcccc cgttgggcgc atggatgagc acgtttttaa
    18901 acgcgccacc accacgcgca ccctgtaacg tttctttcag ggagtccatg ctttcgcggt
    18961 ttacctgcgc tgcaccgatg tagatgatgc acccggcgtg ggatccattg tcgtaataca
    19021 gttttctgaa catgtccgcc gaatgagaca ggctggccga gagtaatgcg ccaagatatt
    19081 ccggcatgcc gtaaatttcc tggttaatgt ccggattcat caggtggcac actttgccag
    19141 ggcgaaactg gaacgcgtcc ttgccatcct gcacatacca ccatgattca agatcgcttc
    19201 cgcgtcgcat gtatttcgcc agtgcgtgcc gtaatttaag cggttcgccg agcatattgc
    19261 ttcgaagctc aaggaatgcg ttaccgaaca caaaccagtc cagcgccagc gccgagaaat
    19321 cctgccggga aagcagcggg tgcgggatgt agcaaccgag taatacattg cgcttaaagt
    19381 aaagcgcaga ctgatgccag gacgtttgcc gggctgctct tgccagaccg taccagtcca
    19441 ccggggtttc ataccaccgc ccgttatcag cacagtacat attgtccagc aggtcatgcc
    19501 cggtcaggcg ataaggacca tcaaatgtga atgcactgag cgatgattct ttcctgagcg
    19561 catcagcgag atcaatgcgt gaactcatgc gcactttttt attttttctg ctcatcagaa
    19621 ctccataacc gtgaaacgct cgttttctcc ttcgccgcca atcggttcgt taatgacagc
    19681 aagcatggtt gcccacgcaa ggtcgccgtg gctgatcccc ctcgcgcggt ccgtttcgta
    19741 agtgataaag ccgcccggtg ttttcacctt acgcacggcg ttaaaggccg cgaccagctc
    19801 gcgttcggcg cgatcgtatt cccaccgccc ggtacgcatt atttgcagca ttttcagtac
    19861 cagcgaccgt ttggatgaca gcgtgaaggt gtacggaata gcagcaggga aaaaccgctt
    19921 cactatctga taaacagcct ccccgttccc gcccgtcaca tcaatgccga tgtgttccac
    19981 gttgtagcga cacgtgaact cttcaatgac tctggcctgt tcttcaaact ccagcccctg
    20041 aacgcgtcgc gtctccaccg ttcgaaaacg gccaccagga acagccggag gaaccaccac
    20101 ggacacagcg ccgctgtcgc cgttgccact gctgccgttt gcgtcatacc caatccatac
    20161 cggacgattc cccatcgggc ggggagcaaa aggtttccag tctttccagt cgtcgtatcc
    20221 gtcaacaccg cagccaatca ggatattcag gttaaatgcc gattcccctt ctcggacaaa
    20281 ctcacacata tagagattga ggaactcgtc ttcggtgttt tcatcacgaa tttcgtcgat
    20341 atcggtgtgt ttccagccgt gtttaaccac atcttccagc gtgacaattt gccgccacgt
    20401 ccgatcaggg cagataagcc cgttatgcag cgttttccag tccacagaaa aacgctggcg
    20461 tttatgcgtg gcctttttct cgttccagcg gtcgccgttc cagtatgcgt atgcctcgtg
    20521 cgtttcggtg gatggcgtgg agaagtaggt gcgccgcagt ccgctgaggg ttgccatagc
    20581 gccagccacc ttgcgcagtt cggcaaagcg actgacccag aaaaattcat caaaataaaa
    20641 attgcccgta taggactgtg ccgacgcagc agaagtgccg agaaaatgca gctctgcgcc
    20701 gttggagagg atgattttat cgcccccttt cagctccaca tcaacttcag ccgcggcctt
    20761 ctgaataatg cttttaaact ggaacgcctg acgacgcgac gcagacaaaa aaatctggtt
    20821 acgctggtaa ggttgtgcca catcgtcacg cagcgccatc agcagtgctt cctgtgcaaa
    20881 ataccaggtc gccccaatct gtcgggattt caggatcatc ctgttacgta tcccggcttc
    20941 cctgcaaagg gtcagggagt caaaccagcc ccgctgatgc cactccagcc tgctgatgat
    21001 tttttcccgc agtgcggcaa tctgttccgg cgtgaaatga tttttgagtt ttttcgcccg
    21061 gcctttcttt cctgtggccg tcgcatccgg ctgaccatca tgcagttttt taagctgccg
    21121 ggtcagcagg tctatttcct tgaagtcacc acctgtttta ttctgttttt cagtgagctg
    21181 gatgaggcgc gcatcgatgg actgcgtgac acgctgcacg ggtggcgttt catcccactg
    21241 gtcgcgtttt ttccacgcat aaatcgtgtt cgggtttatt cccatcagac gtgatatttc
    21301 tgcgggcgga taaccctgcc agtaaagttg ccgcgcacgc tggcgcacaa aagcgtcctg
    21361 aatcattgct ccccctgagt aattacagga agattacccg cgcgcgaaac tgttctcctt
    21421 aaccccctgt tctggccgtt ttcttacaac aaaagccctt tgtatcagcc tgttacgctt
    21481 tgccatcatg actgaagaac cagtcagagg ggcaaaaact atggctaatg aaaaaaagac
    21541 atcccgcaaa aagtttcgcg tggctgtctc cggtgtaacg gcagacgggc gcgaaatcaa
    21601 cggcgacatg ctgaaagctg ccgccaccag ttataacccg tccgtttatg gtgcacgtgt
    21661 gaatattgag cacatcctgt caccactccc cggtagcgag ttttccgcca tgggcgatgt
    21721 tgtggggttg agcaccgaag acataaccga tggcccgctg gcaggtcgca cggcactgta
    21781 tgccgaaatt gagccgaccg ctcgcatgat gtccctgctt aacgatggta aaaaaattta
    21841 ctccagtatt gagctggaac cacagtcaac catcacggga ggcccttacc tgcgcgggct
    21901 ggcaatgacc gacacccccg ccagcctggg cacggaacgt ctggcctttg cggcacaaca
    21961 acgtatgcaa ctgatgacat tcaactgtca gcagggagac gtggcgatgt ttaccgccgc
    22021 tatggagtca gaacttatcg aactcaccga acaacgtcag gaagaaggca cccagtggtt
    22081 taaccgcgtt atggggatta ttggccgtgg ccgcaaagcg gatgacgcca gtttctcccg
    22141 tattcaggaa gcggtggaag gtgtcgcaac gtcacaggcc gacattatcg accgttttaa
    22201 tgtgctggaa acccgccatc agcaggacag ccagaaaatc actttactga ccacagagct
    22261 ggcagcactg aaggaaaaac tgcgcacgca ggacggcgat ccgcagaacc ggttcaccgc
    22321 aacgggcgca gcctccgacc agctggctga cttctgataa gacaaaggag caaatttttt
    22381 atgaatctgg tgatgtcaga tattacccgc aacaagctgg gttgctatat ggcgcagcag
    22441 gcgtcgctta acaatatccc ggtttccgca ctggtatcgc gatttaccgt ggaaccctcg
    22501 gtacagcagc gttttgaaaa cgcctcaaag gaaagcaccg aatttacaaa aagaattaac
    22561 gtgatcggcg tgaccgacca gaaaggcgaa aaaatcctcc tggataccac cgggccgatt
    22621 gcgcgcacga ataccagtta tgacggcaca aaacgccgta acccgaataa cgtggttgat
    22681 ctgaaaaacc gcaaatacca gtgcgaacag gtgaactacg acacgtttat ttcatatccg
    22741 cagcttgatg cctgggcggc acaccctgat tttcagtccc gcatcagcgc acagattgcc
    22801 cgacaggtgg cacttgaccg catcatgatc ggtttcaacg gcacgtctca ctcggatgag
    22861 tccaacttca gcaccaacaa gttgcttcag gacgttaacg tggggtggct ggagcacatc
    22921 agaaccgacg ccagcgaacg cgttatgaat gacgtgacgc tgacctcccg taacatggac
    22981 aacaccgtgg cgcacgcggg taagtatgcg aacgctgatg cactggtaca ggacgcgcgc
    23041 tcatccctgc tggatgaatg gcacaaggaa gctgacgacc tcgtggtgat tatggggcgc
    23101 aacctgttta actcgctgcg tctgcccgtg ctgaacagca tcagcggcca gaatcctaat
    23161 gcggaattac tcgccgggca gctcattctg tcatcgcgca ccattggcgg gctgggcgtg
    23221 ttccttgcgc cgttcttccc ggattcaacg atgctgatca cctcgttcaa caacctgtcg
    23281 atttactggc agaaaggttc aatgcgtcgt ctgatgaaag acgaaccgga atacaaccgc
    23341 atcgccacct accagtccat caatgacgct tatgtcgttg aagactatgg caagtgcgcg
    23401 atggtcactg gcctgaagtt cgccgacagc taatcaactc acggcgggca tcatgcccgc
    23461 ctgtaacgga gagaaaaaat gattactcct gcacagcaac actggcagaa cgtgatggca
    23521 cagcgcgcag gccgggcgaa tgaaggcgtg gaccacgccg cgcgtaccgc gcatgaagag
    23581 gtgctgtatc gtctgcgtct ggcacaggcc cggcttaagg gcgtacaggc cagaagcgcg
    23641 aaagccgcca tcaaaaaaga gttgttgccg gacttttccg gctggattga gggaacgctg
    23701 gaggctgacg gcgggcagca ggatgaagtg attgccacgc tgatggtgtg ggcgattgac
    23761 tgcggcgatc ttccgcttgc gctgcgtatt ggtgcgtatg tggtccgtca taacctcatt
    23821 atgccggata actttggccg tactgctgcc acggtactga ccgaagaaat ctgcaacccg
    23881 gtactgacgc aggccgggac ggatgctgac gcggatttgt ccgcctttat cgaaccactg
    23941 gacacacttt gggaaattgt cgccaaccag gatatgccgg acgaagtgcg cgccaaatta
    24001 tgcaaggcgt gcgcctttgc ccgccgtggc ctgagcgatg cggacagcat ggcctcatca
    24061 ctgaagctgc tgcgcgaagc gatgcacctg aacccgaacg caggtgtgaa acgcgagatt
    24121 gcaacccttt cccgcgccct gaagaaagct gattccgcag ccgcaccaga agatgccagc
    24181 acaccgcaga cgcaggacga aagcagcaaa agtaaaaaga caacgcggaa gcctgcaaca
    24241 cgaaaaacca ccgcgacgca gaaagcgaag cgcggttaac gactgacccc gtcagcgggc
    24301 ggcgtgcgcg gtgttccggt ttgactccgt gaccgtttac accgcgcacc caccgcccga
    24361 ttttttttca ggagtgaacc ccatgagtat ggttgccaga actgaaccaa gacccgcaga
    24421 ggacgacatc accgataccg atgatggcga cactcgcatt tcagcaggtg cattctggcc
    24481 ggatattgtg ctgcgcgagc tgcgtctggc ggtacgactg ccgggccgcg tgaccacctc
    24541 ccgcctgctg catactgcca ccggggccgt ggctcacgtt acccgcgagc tggaagcatg
    24601 gcagcaggaa cagcaggcgg ctggccatca gacgctggcc gatgttccgg cacccgtaat
    24661 taacggagaa agcgtcaatc tctggcactg gcgcaatgct gtttataccg ccacacgcgc
    24721 cctgattctg gagcgttacc gcgatgcgga cacaacggac aagggcgacc gccgggcgga
    24781 cgcactggat atacagacat cggatttgtg gcgtgatgtg agctgggcca tctctgacat
    24841 tctgtgccgc ccgcgaatct ttgcggagtt gtgctgatga aggtgaaggc actggaaggc
    24901 gacaccgtgg attcgctctg tttccggtac tacggcacga cgcagggcgt caccgaaaag
    24961 gtgctggatg ccaaccccgg actctgtcag caggtatttc tggacgccgg gcaggacgtg
    25021 gagatgccgg agccggagaa gaagaaacga gaaatgattc agttgtgggg ggagtagtag
    25081 tgagcaccat tcaaacaggg atcacagagc aggttattgc gtggctcttt gaccacctgc
    25141 caacggtgta tgcagcaggc gcggcggtca gcatttccgc gctgatgagt ctttatgacg
    25201 gacgaacgct ggttcagacc gtaacgggat cgctggcgtg cggcgttctt gccatggccg
    25261 tggccgggtc gttgcgcttc ttcggagttc ctgaagatgc cgtgacgttt ttcggcgcat
    25321 ctatcggttt tatgggcgca gaaaaagcac gcgacaagat cattgccgcc tttaaccgca
    25381 taacccaaaa gggagatgaa taaatcgcag gcttaaagcc ggtaatcacc ataaaaatca
    25441 ttcacagagg tgacgaaatg aaatcgaaag acgaaatttt tgatgccgtt cttggcaaag
    25501 aaggcggcta cgtcaatcac ccggctgaca gaggcggtcc gacaaaatgg ggcatcactg
    25561 aaaaggtggc acgggcgcac ggataccgtg gcgatatgcg tgatttaacg cgcggacagg
    25621 cactggaaat ccttgaagct gattactggt acggaccgcg ttttgatcag atagcgaagc
    25681 tgtccccgga tattgccgca gaactgtgtg acaccggagt aaatatggga ccgtctgtgg
    25741 caaccagaat gcttcagcgc tggctgaacg cattcaatca gggcgggaaa ctgtatcccg
    25801 atatggacac ggacggacgc actggcccac gcacgattaa cgcattgcgt gcatatctgg
    25861 aaaaacgcgg tcgggacggc gagatggtga tgttaacagc actgaactgt acacagggtg
    25921 aacgctatct ggagctggcg gaaaaacgcg aagccaacga atcgtttgtc tacggctgga
    25981 taaaggaacg cgtggcagca tgaagttatg gacttctctg ggcgtcgctt ttcttctgat
    26041 tgccgcatgg ggaacatcca tgcgtctgtc gtggtcgctg ggccgggaga acgccagaaa
    26101 cgaagcgcag gccagcaccc tgaaaagtac cgtcgacacc ctgaatatca tcagcaccgg
    26161 ggtacaggat atgcagcagg tgctggcgca actccgcgtg gaaaatcagc aacgcaatca
    26221 ggacggagaa gccagacgtg aacagctacg caacgatatt gcaaaagatg aatgcgccca
    26281 cgctttgcct gatgctcgtt ttactgacag gttgcgcagg cacgcagaac gcgccacggc
    26341 cagcgccgtc agtccggctt ataccgcaga cgctgaccat accggtaacg cctcccccct
    26401 tccctgacac tcccacatgg ggaaatctcg gtatatgggg cgaccgcctt ctggatgcac
    26461 tggaaacctg taacgcggat aaacgggcca ttgaattact ggaacagcgc agactgcaac
    26521 gactaaacaa cgaggacaac aaccatgctg aaaactgatt ccctgcgtga agccatgacc
    26581 cgttcatgcc gatggtgtca ggccaacccg gaaaaattca ccattttcgt ggagagcggc
    26641 aacattgaaa cgacaggaga aaccccatcg tttgtttacc gctatcagat ggtgatgttt
    26701 gtcatggatt acgccgggga gctggatgac ctcacgctgc cgctgctggc gtggttatcc
    26761 gaaaatcagc cacagttgtt gctcaatccg gagcgtaatc aggacatcaa attctctgcc
    26821 gttatcaatg acgatgacag cgccgatctc ctgtttacgc tccccctgcg ggaacgcgtt
    26881 cgcattacgc gcaacagtca ggggacaccg caggcagaac acctgccgga gccaaaacca
    26941 cgcctgccat cttccgaagg cgactggtcg catgtattcc aagatgtgac gtggggtgaa
    27001 agcgatggat aaggcattca cccgcgtgga tgaaaccttt gaggctatcc gcgacagcct
    27061 gaatcagcag gccatcaata acatcgccag aaagctggca caggatttac gccgcgccca
    27121 gcaggcgcgt atccggtcac agaaagcgcc ggacgggacc gcgtggacac cacgcagacg
    27181 ccgcgtaacc cggatacagg aacgcattcg ctttatctgg aataacgaag tacgcacgct
    27241 gaaaaactgg catcacgaca cggggaaata cgggcgaacc attaccgggt gggatgagga
    27301 taaaaacaat atccgcacgt tttaccggga tgacatcgac cgttttctgg aaatacgcac
    27361 ccggcgcatc aaccaggaca gcacaaagcg cgtccccatg ttcgtaaaac tgcgcaccgc
    27421 ccgctacctg aaagcacgtg cagatgcttc cggtgtgacg gtgggttaca gcggcgtggc
    27481 cgcacgtatt gcccgcgttc atcagttcgg tgagcgcgat caggttgcgc cgggcatttt
    27541 caccgattac ccggtacgtg agctgctggg tatcagccag gcagatgagc gcctgattta
    27601 taacacggtg ctgggccgga ttgcggaggc tgtacggtga gcgcagaact catgcgactg
    27661 ctgagcaata tcatccgcac cgggatcatc tctgaagttg atgagaagtc ctggcgcgtg
    27721 cgcgttcgca gcggcgaact ggaaacaggc tggttgcgct ggaacaccac gcgcgcggga
    27781 gccttcaatg tgtggctgcc gccatcacca ggcgaacagg tggtaattgc ctgcattggc
    27841 ggcaacccgg aaaccgccat gataattggc agcctgtgga gtgatgccaa tccggcaccc
    27901 ggcaaaagcc tgaaagaaat cgtgatcagc gcgccggacg gcgcggtgtt ccgctacgac
    27961 gcggacgctg gcgcactgag cgccagcggc atgaaaacgg ccactttaca ggcatccgtc
    28021 agcgtgaaac tggatacgcc cgtcgtggaa tgcacaaacc ttctgagaac ggcgacgctt
    28081 gacgtcacaa aaggaggaaa gatgagcggc aatatcacgc acagcggcgg caacttcacc
    28141 tcaaacggca ttaccgtgca tacgcataaa cacggtggcg tgaaaggcgg cagcgattcg
    28201 acaggaggcc cgcagtgaca acccgctaca caggaatgaa tccggacggg acgggaaacc
    28261 tgaacgatat ggagcacctg aaacagtcag tcagggacat cctgaccact ccgctggcaa
    28321 gccgggttat gcgacgggaa tatggcagcc ttgtgcctga tttgattgac gaacccatga
    28381 ataacaccac gcgtctgcaa tgcatgagtg ctgccgtgat tgcgctgaca cgatgggaac
    28441 cccgcattgc cctggatgcc atcgacgttg tctggaaagc gggaggccgc gccggggtga
    28501 cgctgtcggg cactgtcatg cagaccatgc agaatgttga attaaccatc acgctgaggg
    28561 agtaaatcat gcccgccgtt gacctttcac agttaccgga ccccgccatc atcgcggagc
    28621 ctgactttga ggcaattctg gctgatacaa aggccatgat gattgcggct tatcccgccg
    28681 aacagcgtga agccgtctcc gccgcgctgg agctggaatc ggaacccctg aacgttatcg
    28741 cccagacaac agcgtttcgt gaaatgctgt tacgccagcg ggtcaatgag ggtgcacgcg
    28801 cctgcatgct aagccacagc gccggggcag acctggacaa cctcgcgggc aatatgaaca
    28861 caaagcgcct ggttatcact ccggcaacgg ataccaccga cgcagtgatg gaaagtgaca
    28921 cctcgctgag actgcgggcg caacgggcgt atgacggtct gagtgttgct ggcccgtcag
    28981 gtgcatacga gtattttgca cgcagcgcca gcggtctggt acacgatgcg cgggccatca
    29041 gcccgtttcc ggccaacgtg acggtttcca tcctgtccac tgagggcgac ggcacagcaa
    29101 cggaggcgtt gcttaatacc gttcgcgccg ttctgaatgc agaggatacc cgcccggtgg
    29161 ctgaccgcct gacggtacag agcgccagaa tcgtgacatg gcggctgaat gcaaaactgt
    29221 acttttaccc cggcccggaa tccgaaccta ttctggccgc ggctgaatcg tcgttcagga
    29281 agtggctggc tgagcagggg cttatcggtc aggacgtggc gttgtccgcc attgctgccg
    29341 cactgcatgt gcacggtgtg caacgcgtgg agataatcga acccacacag aatatggcca
    29401 tcagcgacat acaggcagcg cgctgtgagt cattcaccat cagcgaaggt gggcgcaatg
    29461 agtaattcac tgttaccacc atcagccagc aatttcatgc gttgtgccga agccgtcgga
    29521 acacgcatta cagacattcc ggtagacctc aacacgctgt ggtcgccgga cacctgcccg
    29581 gtgcatctgc tgccttatct cgcctgggcg ttttccgttg accgctggga tcgcaactgg
    29641 ccggaagaga caaagcgaca ggtgattcgt gatgcatggc tgatacaccg acacaaaggg
    29701 accatcagcg cactgcgaag agccgtggag cctctcggct acctgattga agtaaaggag
    29761 tggtggcaac tcaacgagga gccgggaaca tttcgcattg ttgtcggagt acttgatcag
    29821 ggcatcaccg atgaaatgta tcaggaactt gagcgcctta ttgcggatgc aaaaccagta
    29881 agtcgccatc tgacagggct ggcgatcagc ctgagtgtga acggaaatat tttcgttggt
    29941 acgggatgct atcacggcga tgccctgacg gtttatccct acaccccgga gtccattatt
    30001 gtcgaagggg attatttccc tgccccggcc attcatttaa ttgataacct gagagtaaac
    30061 gcatgacagt gaaatactac gccattctga ctaatcaggg cgcagcacga ctggctaacg
    30121 cgacgatgct cggcagtaag ctgaatctga cgcaaatggc cgttggtgat gcgaatggtg
    30181 tattaccgac accagacccg gcacagacaa aactgattaa ccagaaacgc attgcgccgc
    30241 tgaatcttct gagtgttgac cctaacaatc agagccagat tattgcggaa caaatcatcc
    30301 ctgaaaacga gggaggattc tggatccgtg agattggtct ttatgatgat gaaggcgtac
    30361 ttattgcggt ggcaaactgc ccggaaacgt acaaaccgca gttgcaggaa ggcagtggac
    30421 gcacccagac tatccgcatg attctggttg tcacgaacac cgaagccatc acgctgaaaa
    30481 tcgacccgtc tgtggttctg gcaacccgca aatatgtgga tgacaaaatc tcagagcacg
    30541 aacagtcacg acgtcacccg gacgcctcgc tgaccgcaaa aggttttact cagttaagca
    30601 gcgcaaccaa cagcacttct gaaacactgg ccgcaacgcc gaaagcggta aagatcgcgt
    30661 atgaccttgc taatgggaaa tataccgcac aggacgcgac cacagcacga aaaggccttg
    30721 ttcagctcag tagcgctaca agcagcacat cagaaacgca ggctgccaca ccaaaggcag
    30781 tgaaggcggc atatgacctt gcagcaggta aggcacctgt cagtcacacg cacccgtgga
    30841 gccagataac ggatgtgcct gcagcttcac tgacggtaaa aggcaccgtg caactcagta
    30901 gcgccactaa cagcacgtca gaaacgcagg ctgccacacc aaaagccgtg aaggctgcat
    30961 atgaccttgc caatggaaaa caacctgccg acgccacact gaccgcactg gcaggccttg
    31021 ccactgcggc agacaaacta ccgtatttta cggggaatga tacagccaac ctgacaaccc
    31081 tgactaatgt tggacgggat attctggcta aaacaagcaa acaggaggtt attcattatc
    31141 ttggtttggg agctacaaac ggatacgtgg gacgcttggt gaatacccgg gttttcacgt
    31201 catcaggtac gtacaccccg acgccaggaa caaaacggat cagggtcaca ataacgggcg
    31261 gcggtggcgg agggggcggc tgcaaggcta tatccaataa tgaaacgttt ttcggtgctg
    31321 gcggtggggc cggtggaaca ataatttcaa taatgacccc gacacagaat agttatccag
    31381 tcactatcgg cgcaggtggg gccggtggtg ttagtgcgac gaacggcacc aggggcggga
    31441 atagcgtatt cgcatcgtta attgctcctg gtggcgcagg cggcggaaag tcaggagtca
    31501 caaacacaaa cggtggtagc ggcggcgtgc caagtactgg cggtatcaac atcattggtg
    31561 gaaatggagg cgacggtcag tccggaaata tcggcgtcag cggtgaaggc ggaacatcgt
    31621 actggggggg cggtggacgc gcaggcgctg gcggtggtgt tagtggtaag gcatatggtt
    31681 caggtggcgg tggcgcatac gatgccggtt atagcggaac cagtatgaca ggcgggaaag
    31741 gtgctgctgg gatttgtatt atcgaggagt ttgcataatg aatgcgtcat atgcagttat
    31801 tgaaaatggg atggttgtga atgtcattgt ctgggatggc gaggctgaat tcacagtgcc
    31861 ggataatcag cagctcattg atatttctga tatcagtgag catcccggaa tcggctgggg
    31921 gtattcagac ggggtattta ctgcgccgct ccctccggaa cgttctcatg atgaactggt
    31981 agctgacgct gaacagaaaa aacagtcgct gatagacgca gcaatggcca atatcagcgt
    32041 gattcagtta aagctgcagg ccgggcgcaa actgacgcaa gaagaaacta cccgacttaa
    32101 cgttgtgctg gattacattg acgcggtgac agcaactgat accagcaccg cgccagatgt
    32161 catctggcct gaactgccgg aggcgtaggc cattcaatat ctggcccact ggaagtatcg
    32221 accagctcca gtgcgtccag ataatccagc cacaaattat attgcgccag ttcctcacct
    32281 ttcagacgac caatagccgc tttaccagcc cattgtttac tgttcatata atcgttagcc
    32341 tgattaatca attgctgctt ttccagttcg gctgcagcaa tctgttcctc atgtgttggt
    32401 ggtggaattt cagaccatgc aggaaaacca ttttctccag cgatacggat ttttcctttc
    32461 ggcggtaatc cggaaaactc aatatacgct tgctcatcaa cttcaacagc atcatctggc
    32521 catgagtcag cttgagtgta atcctctttc atttccagtg gatagaaaga gtttgtagtc
    32581 gcggaatata tgtaattcat ttttcactcc atatagctaa attaacagcc taacgctaaa
    32641 aatgaagcgc cgagacctgg agtactggct ctggatataa atttaaccgg gtcggaacta
    32701 aaacctgcgc aggcaatata accaacagac ccgctatctg gtgtgtagtc ttgtgagacc
    32761 aaaacacgca gacatcggtt tggaaatgca atcggaaaat gggttaccac atcctgtgca
    32821 atgcctggtg cgccgattga gccccactga agaataaaac cagatggtaa tttttgatat
    32881 ccagtacctg aaacagaaag cgtgaagcta cccatatcag gtatctgatt cgtccctgtc
    32941 cccacattcc tttttgccgc ttctcccaaa ccaacgttta tgaaaatgca gaaataacaa
    33001 gcaaatggca tcattcctgc ttttgtcagg gagatctatc atgcttattg gttatgtacg
    33061 cgtatcaaca aatgaccaga ataccgatct acaacgcaat gcgctgaact gtgcagggtg
    33121 tgagctgatt tttgaagaca agataagcgg tacaaagtcc gagacctagg gctgacactg
    33181 ctgttcttga tgcaaattaa aggatttaat agtgagtagc ggccttacta atgtaaggcc
    33241 gctataatca ttttattaat tgcattaatc gtgttttggc catactttca atgcaatttc
    33301 ccccaacttt ttaccccgct ccaggatttc atcctcatcc catttatcct taactataag
    33361 tggaatgttc agtcgtagat tggtgtggac gatgagagca tcacgttttt tcagaaatac
    33421 agcattctga acagaacggt ttacgctaag gttaagcaaa gttagatttc ccaacgtagc
    33481 tatcgcttgt tgccgtttcc ttaccagtag ctgttcaggg gtaagatcgg ttccagacag
    33541 aacaatttgg ttcaataccg tagcatctga atttgtcacc atatgaccat tttcgagagg
    33601 ccaacaggaa aaccaacttt gaggcataag atgatcgata tcgagattgg aaagatttgg
    33661 accatcaggc ttctctgtct tcacttggcg acaaagttct ctttcaagtt ccgttaacat
    33721 tgagcgcatt ttcggtgcgt cgagcctgcc aggataaagt ggagcattga tgcaagcatt
    33781 gagaaattct gagtcaccag gccaacgtga ggcttcgcca tttaagctat tgaggatatt
    33841 acgtaactca acactggaaa tttccgtttt agacaagtgc cgcaatacat tcataaatac
    33901 attgttgtaa ttctttggcg tcaggccaca tacggctctt cgtactacgt aggagacaag
    33961 atcattatac atggctgctt tctcatcatc agcgatgtta gctatcgaaa tgaacaaagc
    34021 aagcggataa agtgtcgtca catcatagtc tgcgatgcga tatccaaagt gtgagatggg
    34081 ggttgtgcca aaaccatcaa ccaattcttt atattgtgat gcatattgtt tgaggcgctt
    34141 tacttgcaga tctgctcgtt gtgaagacaa gtccttactt acataatcac gatactcatt
    34201 gtaaaggcga gacagatcaa tttcacgctg cctttctgat tgcaatgtcg catgtactag
    34261 ccactccatg cgtggtttat taatacgtcc acggcgttgc ttttccgacc agtatttatc
    34321 ttcaaagctc ttccactcat tttcatataa ttcaatagca ttaatatttt catgctcagc
    34381 gcacataaag atatagttgc gaataagatc cgtggcatga agttccgccc ctcgcccatt
    34441 taatgtttca aaaattattt gggcatcatc ttcagcttcg agaaatatgc ttaccagttt
    34501 cagatctgtt aagacagcct caattagagc tacagcattt tcttgtggtg agtggttttc
    34561 tattttaatc cattttataa aggcttcagt aaaaaaacat aatgcttcta gtgatggcgg
    34621 gtgattaaaa tgcttacgca acgtaccatg ctgcgtgaaa ctatcagaga atacgtcccg
    34681 gagatcgtca atattttcaa cattaaaact ttgaataaaa tgagtttgat cccgaaaagt
    34741 tggccatagt ttgaagcgtt ctacttcttt atttcgcatt gtgtcttcgt ttgagttttt
    34801 caggcaaggc gaaatgagag cctctaagct gaaaagatcc gtagcacgta atgctaatcg
    34861 gatggatgcc agaacatatt gaagagtggt caatcgttgc tgaccatcaa taatatgtat
    34921 ggaatctaca cctaataatc ctttttttga ttgaggttcc agtacaaccg caccaaggaa
    34981 atggggagtt ggttttgtac ccgagagccg ggattgtgct ttctctagga tatcctccag
    35041 tagagctgac cattggtctt gctgagtcca tacataggca cgttgataga atggaacaca
    35101 gtattgtcgg cggtcttgaa aaagttgttg gacagttagc gtctcggatt tcatggtata
    35161 cctgtaagcg acattgtaca aaagtgagga gttaatctga tttagaacaa tcattttatt
    35221 ttgctatgat acaacgtatt tgttaccggt taagcaaaaa acgcgtctga acgctgacgt
    35281 tttagggctt tactggttat tctttcttat ctcttcatca tcccatcggc atcctgtcga
    35341 ggttgttgac ttgttgttat ttattttgtc taggcgctgt ttaattatta ttgatagaac
    35401 tgatggtgag aggtgattga aaccgtaggc acgtcgtttg caaggacgtg ctacgactgg
    35461 ctggtgaatt tccgatagtg cgagtattga atgatttcct acgtgctaac tagtgaacaa
    35521 acaactcttc agtagactct caggtatcat tcagagtttc ctgaacgaaa gttttagctc
    35581 aatctttatc tgcagtatgt ctaactgaaa aactatcgtt gctggtggct tttacgatca
    35641 tctccacatc gtcataacgc ttgccaatgt gttgggttaa ttcttccttt aacgcgtcca
    35701 cagcgccgtt tggcatttgg tcatttgtct ttggctatgg agatctcaat acgcataaca
    35761 cttcttttgt actgcgtttg tagacagtat tattcttatc tgtgtaaata aacagtatca
    35821 agacttcgtt ttagctgcat aagaaaaaag agatggatac attcggaaag cttttgatgg
    35881 tggtaggcta agtgaatagc ctaaaggtgt tttaccccaa ttattccccg gtatttctcc
    35941 gcataaaaaa caatcataaa aaaaccagcc ataataggct ggtttttaag ggatttttgg
    36001 tcggcacgag aggatttgaa cctccgaccc ccgacacccc atgacggtgc gctaccaggc
    36061 tgcgctacgt gccgactcgt ggctgctaat actaccgttt tccacaccga ttgcaagtaa
    36121 gatattttgc taactgattt ataattaatc agttagcgat aaaacgcttc tcgtctgtca
    36181 gcacttgcaa taacaaactt aactgtggtt tttcatcttt cactctttca ccacgtaagt
    36241 tgtaagtgcg gtatttaccg ttattgttca gcaccagcgt ctttttcggg gtggtaattg
    36301 ccagcgtatc gttatccgct gcagtaaccc agtaatgacg gcgttgaggg ttgaacaaat
    36361 cctgaccttg cgaatattcg ctggcaggtg tgctgacatg tagcaggcgt tgcatcagcg
    36421 tcgtcatcag atcggtatga tcagtcagag cattaatacg ctgcgccggc gtgcctggcc
    36481 agtgaatcac taatggcacc tgcagatgac cgtgggacca gtcaaaggtt tcttcgtctt
    36541 cgctcagcgg aataccccga ccggcagtga taatcaccac cgtattgtcc agtttgccag
    36601 aatcacgcag tgcattgagc acgcggttga tctggtcatc gacattgcct gccgcccggc
    36661 tatatttccg tgcaaatgcc tgctgattgc tgtcgtcaat gttagtgcca ttgaaagaga
    36721 cccacgagaa ccagcggtta tcttcttgtg cgtagcggcc cagccagttg atccactgcg
    36781 tggcggtctg ctcgtcggat tgggtgcgta cgctcggcat cgagaaatct gacaacaatg
    36841 cctggcgata cagcgggctg gtaaagccat ctgatgagaa taatcccagc tgatagcctt
    36901 gctgattaag cgcagtaatt aacgccgcag gggtacgggt cgacagaatg ccgtccatat
    36961 agctcggcga gatgccatag aacaggccaa agatgccgtt gtctgtagtg ttgccggagc
    37021 tcatatggcg cgtgaacgaa atattttgct cagcaaaacc tgccagcgca ggcatctgct
    37081 tctcgaagcg tgagtagttc aggccatcga cagtaatcaa cagcacattc tgcccggtgc
    37141 ccatatcgcg atagcgcagt tcgcttaacg gatactgaac ggaaacggcg tctggattac
    37201 cttgctcaat aagacggcgt tgatactcct gcgcatcaag cagaccatgc ttctcaagaa
    37261 aacgtcgcgc cgtcatcggg tacgaaagcg gcaggttagc gcgctgcatg gtgatcgggc
    37321 gatagaagtt ggcatcggcc cagatataca ccacatgcga ggcgataaag gcgataaata
    37381 agaatgcggc cagcgggcgc gcgaagcgcc gacgacgcgt caggctgcgc agcttttgcc
    37441 agctccacgt cgcaaacacc agttcaagca ataaaataac cggcacgctg atgaacatca
    37501 gctgccagtc gcgcgccatc tcattttcgt ctgggttgat aaccagttgc cagacgatgg
    37561 gattaagatg gagatggaaa cgagtaaaga cttcgctatc gatcagtaat agcgtcattc
    37621 ccgccgttgc cagaatgacg gacaaaaacc tcatcagcct ctgggagccg acgataaagg
    37681 tcagcgggaa gaggatcagc aagtaggtgg cgaacaccag gaagctgaaa tggccgataa
    37741 tgcttacgta ggaataaatg cgaccagcaa gcgttgtcgg ccagtcggcg ataaacaggt
    37801 aacggctgcc aatgacgagc gaaagcagaa tattgaacag tgcaaaccag tgcccccaac
    37861 tgaccatctg ggagactttt tcacggtagc gctgacgatg agttaccata acctgttatc
    37921 tgtttccctt agtgcgcttt gtcttcgttg atagaggact gtaaggcgcg ggcaaaagag
    37981 ttggcaattg cctggcgttg ggccggggca atgctggtat tgataaggtt agtgaccatg
    38041 ttgcctaaca ccatcaggga aaggtcggtc ggagccttat gtttttccag tacgttgagc
    38101 agctctgcga gcaattgttc aacctgttca tcactgtagc gggaaatttg tggcataaat
    38161 cgaaatcagt tagttgatga aagggcaaca tattaccgta gcaacggttt tttttctgct
    38221 tttttatgcg ttaaatcatt ctcgttacgc tgccttctgt aaaatgaccg ccatctttta
    38281 ttgcgtcgct taaccggcgg tggttgaata ccgcccggtc ttaaaggaga gtttatcatg
    38341 agtctggata tcaaccagat tgctctgcac cagcttatca agcgtgatga gcagaacctt
    38401 gagctggtgt tgcgcgattc attgctggaa ccgacagaaa ccgtcgttga gatggtggca
    38461 gaactgcatc gggtctatag cgccaaaaat aaagcttacg gcttgtttag cgaagagagt
    38521 gaactggcgc agacgctgcg cttacagcgt cagggcgaag aggactttct ggcatttagc
    38581 cgcgcggcaa ccgggcgcct gcgtgacgaa ttagcgaaat atccttttgc tgacggtgga
    38641 ttcgtgctgt tttgccacta ccgttatctg gcggtggagt atctgctggt ggcagttctg
    38701 agcaacctga gcagtatgcg cgttaacgaa aatctcgaca tcaatccaac ccattatctt
    38761 gatatcaatc atgcggatat tgttgcgcgt atcgatttaa ccgaatggga aaccaatcca
    38821 gagtccaccc gctatctcac tttcctgaaa gggcgagtag ggcgcaaagt ggcggatttc
    38881 tttatggatt tcctcggggc cagcgaaggg ttaaacgcga aagcgcaaaa ccgtgggctg
    38941 ttgcaagcgg ttgatgattt cactgccgaa gcacaactgg ataaagcaga gcgacagaac
    39001 gtgcgccagc aggtttatag ctactgtaat gagcagctgc aggcaggcga agagatcgaa
    39061 ctggagtcgc tgtcgaaaga gctggcaggc gtcagcgaag tgagtttcac ggagtttgcg
    39121 gctgaaaaag gctacgaact ggaagagagc ttcccggcag accgtagcac actgcgtcag
    39181 ttgacgaagt ttgccggtag cggcggtggc ttgactatta actttgatgc gatgctgtta
    39241 ggtgaacgca tcttctggga tccggcaacc gataccctga ccattaaagg cacgccgccg
    39301 aatttgcgtg accaattgca gcgccggacg tctggcggca attaatcggt tttgtgttct
    39361 gaatgccaga tgcggcgtga acgccttatc tggcctgcaa aaaatagcaa taccgtaatc
    39421 aggcataatc tgcagataca aaaaaccccg ccggagcggg gttttttaca acttattcag
    39481 caattaagcg cgaacgaagt cgatgtgctg cagcttcggt ttgtacgggt gacgctgtac
    39541 gtcctgagct ttaactttga tttctttacc gtcaacaacg atggtcagaa cttcgctgta
    39601 gaattcagct ttagcttgca tgttcatgac tttgtcgtga tccagctcga tagccagcgg
    39661 cgcttctttg ccaccgtaga tgattgccgg gaacttgtta gcggcacgca ggcggcggct
    39721 cgcaccctta ccctgctctt tacgtacttc tgcgttgata gtaaacattt ctttctctct
    39781 taaattaatc ctgctacagg cgacccagca acaggtaagt gatctgcttt gcgtatgcaa
    39841 aagcgggcga gattctatac tcaatcgctt tatacatcaa tcaaaactac cattaaccgc
    39901 gtaattcgtg cgcccgacga aaacgacctt cgtaatcgaa cactttttca cgcacttgcc
    39961 agtactgacc tttcatgcgg gcaacgacaa aatccgggtg tcgcaataag gcttgctggg
    40021 cgaggatatc ggcggcggtg atccagcgca gagggatgcc cggtgtgcgc gtatgcgggc
    40081 ggataaaaag ctgctcgaag gcagttcgct gggcgggcgt ttgcagacgg aaacgctcac
    40141 tcacatccgc gccgtcttca tcgtaatagg tgattttcaa ccattcgcct ttctcgtcgt
    40201 gctcatgctg caaagacatg ccgctacagc gtaataccag cgcatctttc agtcgtagcg
    40261 ccgcttttaa catatcatcc ggatcaacca gtaccgtgtc acattcgcgg cagcggcgag
    40321 cggcaatatc attttctgcg ttacattgcg ggcaattttt aaaacggaaa cggaagtcac
    40381 actgttcgcg atgaccgtcg tcatcttcaa accatccctg acagcggcga ccaaagtgtt
    40441 caatcaatgt cccgtcggcg gtcgttttcc cccaaaaggt gttggcaaaa ccgcaggcag
    40501 ggcagaaaac ctgtaccgga acgttgtcac ttttgccttt cggtgtacca acttccggcg
    40561 cgtagagatc gtgaggatta cccgcataat caagaattaa acaatcagtc ttgcccggag
    40621 cgagacgcag accgcgcccg acaatttgtt ggtaaagact cactgattcg gtagggcgca
    40681 gaatggcgat aagatcgacg tgcggggcgt caaatccggt ggtcagtact gcgacgttga
    40741 ccagatagcg aaaacgctgg gctttaaaat cttcaattaa cacatcgcgc tcagcgccgg
    40801 gggtgtcgcc agtaatcagt gcagcatctt cggcaggcag taatcccaca atctcttttg
    40861 cgtgttcaac ggtggcggcg aaaatcatta cccctttgcg cttttcggcg aactccatga
    40921 tctggctgat gatatgtggc gtaatgcgtt gctgtttttt cagctcacgg ttgagatcag
    40981 cttcgctgaa cagcccgtta ctctgtgcct gcaagcggct gaaatcgtat tgcactactg
    41041 gcatatccag tcgttctggc ggcgtcagat agccgtgttt aatcatataa cgcagcggca
    41101 gctcataaat gcagtcacgg aaaagggctt tctcatcgcc gcgtaccatg ccgtgataat
    41161 ggaactggta gatccagcct ttgcccaatc gaaaaggcgt ggcagtcagc cccagcaggc
    41221 gtaagtgggg attcacttta gtcaggtgag tgaggatttg ctgatactgg ctctcttcat
    41281 cgtcaccaat acggtggcat tcatcgacaa tcaacagcga aaattcaccc tgaaaggcat
    41341 caagattacg agcgaccgac tgcacgctgc caaataccac tttaccgtgg ctctctttgc
    41401 gctttaaccc agcggcaaaa atatcggctt ccagccccag cgcctgatac tttgcatggt
    41461 tttgcgccac cagttctttg acgtgtgcca gcaccagaac acgaccacgc gccagccgtg
    41521 ccagttcggc aatcaccagg cttttacctg cgccggtggg cagcacgata acggcagggg
    41581 ttttatgacg acgaaaatgg ttgagcgtgg catccacggc ttcttgctga tatgggcgaa
    41641 gtgtaaaaat catggtctcg cgtaggtaga ttattctgct aatagtatgc catggatctt
    41701 tttcccttga gggatgttat tagaccgcta tactgggcag acaacagttc agattttcgg
    41761 gtcaatgccc gacctccgtt tttacaggca aaatcacaca catgcgactt gataaattta
    41821 tcgcacagca actcggcgtt agccgtgcta ttgccgggcg tgaaatccgc ggcaatcgtg
    41881 tcaccgtcga tggcgaaatc gtccgtaatg cagcgttcaa actgcttcct gaacatgatg
    41941 tcgcttacga tggcaacccg ctggcgcagc aacacggtcc acgttacttc atgctcaata
    42001 agcctcaggg ctatgtttgc tccacggacg accctgatca cccaacggtg ctctattttc
    42061 ttgatgaacc ggtagcgtgg aaactgcatg cggcggggcg gttggatatt gataccaccg
    42121 gtctggtgct gatgactgat gatggtcagt ggtcgcaccg cattacttct ccgcgccatc
    42181 attgcgagaa gacctatctg gtgacactgg aatcacctgt agctgacgat acggcagagc
    42241 aatttgctaa aggcgtgcag ctgcataacg aaaaagatct cactaagcct gcggtgctgg
    42301 aagtgattac cccaacgcag gttcgtctga ccatcagcga agggcgttat catcaggtga
    42361 aacgcatgtt cgccgccgtg ggtaaccacg tggttgagct gcatcgtgaa cgtattggcg
    42421 gtattacgct ggatgctgat ttagcccccg gtgaatatcg tccgttaact gaagaagaaa
    42481 ttgccagcgt cgtctaactt ttcaatgact ttcaggagcc cgttgtgacc acccgacagc
    42541 attcgtcgtt tgctattgtt tttatccttg gcctgctggc catgttgatg ccgctgtcga
    42601 ttgatatgta tctgcccgcg ctaccggtaa tttcagcgca gtttggcgta ccggcgggca
    42661 gtacgcagat gaccctcagt acttatattc tgggctttgc gttggggcag ttaatctacg
    42721 ggccgatggc agacagcttc gggcgtaagc cggtggtgct cggcggtacg ctggtgtttg
    42781 ccgccgccgc ggtggcgtgt gcgttggcaa acaccatcga tcagctgatt gtgatgcgtt
    42841 tcttccacgg gctggctgcg gctgcggcca gcgtggtcat taacgccctg atgcgcgata
    42901 tttacccgaa agaagagttc tcgcggatga tgtcgtttgt catgctggtg accactattg
    42961 caccgctgat ggcaccgatt gtcggcggtt gggtgctggt gtggctgagc tggcattaca
    43021 tcttctggat cctggcatta gcggcgattc tggcttcggc aatgattttc ttcctgatta
    43081 aagaaacctt accaccggag cgtcgtcagc catttcacat tcgtaccact attggtaact
    43141 ttgcggcgct gttccgtcat aagcgtgtcc tgagttatat gctggccagc ggtttcagct
    43201 ttgccggaat gttctcgttc ttaagcgccg gaccgtttgt ctacattgaa attaaccacg
    43261 tcgcgccgga aaactttggt tattactttg cactaaacat tgttttcctg ttcgtgatga
    43321 ccatttttaa cagccgcttc gttcgccgca ttggcgcgtt aaatatgttc cgctcggggt
    43381 tgtggataca atttattatg gcagcgtgga tggtcatcag tgcgctgctg gggctgggat
    43441 tctggtcgct ggtggttggc gttgcggcgt ttgtgggctg cgtgtcgatg gtgtcatcca
    43501 atgcgatggc ggtcattctt gatgagtttc cccatatggc gggaacggca tcttcgctgg
    43561 caggaacctt ccgttttggc ataggggcaa ttgttggcgc attgctttct cttgcgacct
    43621 ttaactctgc atggccgatg atttggtcaa ttgcattctg cgcaagcagc tccattctct
    43681 tctgtctgta cgccagtcga ccgaaaaaac ggtgatctat tgcacaacga ggaagctaaa
    43741 aggcttcctt tgttgatgca tgtcaaccac aaatctatca ttcccccgat atatgtttat
    43801 tttatgtaaa atcaatttat gtaaaaagtc acatcattgt agttaaaaag gttgagttag
    43861 atcgcagaaa cgggtacata tagccccgca aacgtgacca cgcccgcaga tattacttaa
    43921 atcagagcca tagaggccac gcaggcgagg catcaatctt tacgatctgt ataaagacgg
    43981 attgttgatg atgtgttaaa attgatgtaa acaaattgtg aagtgaatgt acttccgggg
    44041 aaaataagtg acttcattac aactctcaat cgtccatcga ctgccgcaga actatcgctg
    44101 gtctgctggt ttcgcaggtt cgaaggttga accgattccg caaaatggac cgtgcggtga
    44161 caacagcctg gtggcgctta aattgcttag cccggatggt gataatgcat ggtcggtgat
    44221 gtataaacta agccaggcgt taagcgacat cgaagttcca tgttcggtgc tggagtgtga
    44281 aggtgagccg tgcctgtttg taaatcgcca ggacgagttt gctgcaacat gccgattgaa
    44341 aaattttggt gtggcaattg ccgaaccctt ttcaaactac aatccttttt aagcgtcagc
    44401 tcaacgccag tagctgacgc gtatactcct gctgcggtgt ggcaaacacg cgcgcgcacg
    44461 gtccttgttc cactacttcc ccttgtcgca gtacgataac ctgatgacat aacgcgcgga
    44521 caacgtgcaa atcgtggctg ataaacaaat aggccagttg atgcttttgt tgcaatgatt
    44581 tcaatagcgt caatatttgc gcctgtaccg ttttgtcgag tgatgatgtc ggttcatcaa
    44641 gtatgatcag cgagggctta agaattaatg ccctggcaat cgcaatacgt tgtcgctgac
    44701 caccagagaa ctccgccgga taacggtggc gtgtttcagg atctaatccc acttcatgca
    44761 tcacggctat cacttgttgt tcgcgttgtg cggcagaaag cgtcggctgg tgaacccgta
    44821 agccttcctc aataatctgc aaaacgttga gtcgtgggtt gagcgaggag tttggatcct
    44881 gaaataccac ctgaatgcga tgacgaatag gtaacagctg gcggcgattt aaattttgca
    44941 gtggctgacc gtcaaagatg atgctgccct gagaattaat cagtcgcagc agcgccagtc
    45001 ccgtcgtact tttcccggaa ccggactcgc ccactaaacc cagtgtttca cccgctcgta
    45061 gcgtaaaact gatgtttttc accaccacat tatgatccac aatgcgcttc aaaatccctt
    45121 tgcgaatggg gaaggcaacc tgaagctgtt caacatccag caacgttgag gcaggttctg
    45181 gcaacggcac tggatcgcct gacggttcac tgttgagtag cttttgtgtg taaggatgag
    45241 tgggtgaggc aaatagcgta gcggcgtaat tttgctcgac acagcgaccg ttttgcatta
    45301 ccgccacgcg gtgggccagt tttctgacaa tgctgaggtt atgagtaata aacagcatgc
    45361 ccatattcag ctcgccttgc agttcgcgca acagctgtaa aatctgcgcc tggacagaga
    45421 cgtccagtgc ggtggtcggt tcatcggcaa ttaataattc cggtcgcgtt aacagcgcca
    45481 tcgcaatcat cacccgctgg cgttccccgc cggagagctg atgcggataa tctgtcagcc
    45541 gttttgccgc ctggcggata ccaacgcgat caaggcagtt aagaatttcg ccacgagccg
    45601 cttcccgacg catcccgcgg tggagtgaaa gcacttcata aagctgtttt tccagggtat
    45661 gcaatggatt taacgacacc atcggttcct gaaaaatcat ggcgatctta ttaccgcgta
    45721 caccgcgcaa cgtttgatcg ctggcgtgaa gcagcgattc gccatgaaaa cgaatatcgc
    45781 cggagagata ttcaaccggc ggggaaggga gcaggcgtaa aattgacagc gcggtaacgc
    45841 ttttgcctga acctgactca cccaccagcg ccagcgtttc gccagcctca atctgtagtg
    45901 aaacatcatt gactactgta cgtacggttt gctgatggcg aaaacccacc gacaaatttt
    45961 caatcgctaa cagagtttgc gtcatgctac accgccttat taggatcaaa tgcgtcgcgg
    46021 acggcttcac caataaagat cagcaaagac aataatatcg ccaccgacaa gaaggcggtg
    46081 atcccaagcc acggggcctg aaggttattt ttcccttgta acagcagttc accgagtgac
    46141 ggtgaaccga gcggtagacc gaagccgagg aaatcgagcg aggtcagggt ggttatcgaa
    46201 ctacataaaa taaacggtaa aaaggtgagg gtcgcgacca tggcattagg caacatatga
    46261 cgcaggatga tactgcgatc gctgacgcca agcgcctgtg ccgcacgaat gtagtcgaaa
    46321 ttacgagtac gtaaaaactc cgcccgcacc acgccgacca gactcatcca gccaaacaag
    46381 acagtaattg ccagcagcca ccagaagtta ggctgtacga cgctggaaag taaaataatc
    46441 aaaaacagcg tcggcatccc cgaccatact tcaataaagc gttgtcccca gagatcgact
    46501 ttaccgccgt aatagccttg tagcgccccc gccagcacgc ccatcacgct ggaacagaga
    46561 gtcagcatca ggccaaacag aaccgagatc cgcgtgccat agagaatgcg tgccagcaca
    46621 tcgccgccgt tggcatccgt tcccagccag ttttgccggg agggtggaga agggaagggc
    46681 ttatcggtag caaagttgat actggtagca ccaaagcgaa tcggtgccca cagtacccag
    46741 ccgttatttt ccagccgttg tttcagccac gggtcctgat aatcagcctg acttgccagc
    46801 gggccgccaa aatcgctttc gctgtagttt ttcaacaacg ggaaatacca actgccgtca
    46861 taacgtacca gcaacggttt atcgttggcg ataagttcag aacacaaact caaaccaaac
    46921 aaaacgagga aaatccataa cgaccagtag ccgcgacggt tatggcgaaa acgcgcccaa
    46981 cgggcctgat tgacggggct gagtcgcgac attaacgtcc ctcaaaatct atacgcggat
    47041 cgaccagcgt atagctgata tcactgacaa tattcagcag caggccaatc agggtgaaaa
    47101 tatacaaggt accaaacatt acaggataat cgcgcgagac ggtcgcttcg tagcccagta
    47161 agccaaggcc attgagtgaa aacatcactt caatcagcag cgagccggta aaaaacatgc
    47221 tgataaacgt cgccggaaaa ccggcaatca ccagcagcat ggcgttgcgg aacacatgtt
    47281 tccagagaat atttttttca cttacccctt tcgcacgcgc ggtcaccacg tattgcttgc
    47341 gcacttcatc aaggaatgag tttttggtca gcatggtcag cgccgcaaag ccaccaatca
    47401 ctgtcgccag caccggcagc gtgatatgcc acagataatc ggtgattttc tgataccacg
    47461 gcagcgaatc aaagttagcg gaaaccaggc cgcgtagagg gaacaggtcg aaatagctgc
    47521 cgcccgcgaa gaagacaatc agcaggatgg caaacaaaaa ggccggaatg gcgtagccga
    47581 tgatgataaa tgcgctactc cagacgtcaa agcggctccc attataaaca gctttgcgaa
    47641 tgcctaacgg aatcgacacc agatagataa tcagcgtgct ccacaatccg agggtgatgg
    47701 aaaccggcag actgtcttta atcagcgtca gcaccgaggc gctgcgaaaa aggctatcac
    47761 caaaatcaaa gcggatgtag tcccagagca ttttgaagta acgttcgtgg atcggcttat
    47821 cgaaaccgta gcgatgagtg atctcggcga tcacttctgg atctaatccg cgtccgccac
    47881 ggtaattact gtcgctgata ttgccgacgc ccgtttgcgc atggctggcg cgaatacctt
    47941 caccgcctgc gccgggtaat actccggcat taccaaactc aatggcggcg atggcctggt
    48001 cgaccggacc gccaggcgca atttgcacga tgaaaaagtt gatagtgata atcgcccata
    48061 acgttgggat caccagcaac agacggcgaa tcagataagc gcccatctac tctccctgtt
    48121 gtctggctga cggcagtttg gccgctttat taacgtcata ccaccaggta tcgataccca
    48181 ggctgtaaac agggcgtaca gcgggttggg agaatttatc ccaccaggcg agacggtctt
    48241 ccgccatgta ccacattggc agcatgtaat aattccacgt taatacgcga tccagtgctc
    48301 gccctaacgg cagtaatttt tctttatttc cctgcgcggc aataatttga ttgatcagcg
    48361 agtcgataac cggactttgc acgccggggg cattataagt ggaattgata tattccgatg
    48421 accaggaaat ctgtaaatcg gaactgggcc acggcatcgc ccgccatacg cgcggcatca
    48481 tgtcatagtc gcgactgcgc atgcggttgg tgatttgcga gttatccacc ttgcgaatgt
    48541 ccatgttgat acccagccgt tgcaggctgt gctggaacgg caatacccac tgactattgc
    48601 tgcttgcggg aagcaataat tcaaagctga gtggctgacc cgttgtggca ttaacgcgtt
    48661 gctgaccctt cagcacccag cccgcttcgt tgagaagttt gtcggctttt aacaggttgt
    48721 cacgatcgta gccatcgcct ttagataccg gcggctggta gatttgtgtg aagacttctg
    48781 gcggtagatc ttttttcatt ggtgccagaa gcaccagctc cgcggcgtcg gggtaatttc
    48841 tggccgcgta ttcggtattc tgaaaataac tgttcgtgcg actccaggcg ttgtaaaaca
    48901 acgccttgtt catccattca aagtcaaagg cgagggtgat tgcttcccgg acccggcgat
    48961 cgctgaatac cggacgttgg atattaaacg ccagccagcg cgtatcctgg gctgattcgt
    49021 tcttttgctc atctttgatg atgtattttt tatcgaaatt tttaccggta taacgcgtgg
    49081 cccagttttt agcgtcgttt tccatacgca aatcaaaggc acctgcttta aacgcttcaa
    49141 aggcgacatt atcatcgagg taataatcgt agcgaatggt gtcgaaattc cagcgtccac
    49201 ggtttaccgg taagtttgct gcccagtaat ctttcacgcg ggaatagaca atattttgcc
    49261 ccattttcca ggacgtaacg cggtacggac cactggcaag cggaggcgtg gcgagcgggt
    49321 cgctaagttt gtgatccttc cagtactttt ctggaaatac cggcagcgaa aacagactca
    49381 gcatatcttc tttgctggct ttagctaact caatgcgcac ggttaacggt gcaatggctt
    49441 tgacggtggt gcctttgtag accagacgaa attgcggtac gccttcggtc ataaattttc
    49501 gaaaagtaaa ctctacatcg cgggcagtaa tgggcgaacc atcatgaaaa cgggcgcgcg
    49561 gattaatagc gacctccacc caggaataat cgtcagcata gcgtgcgctt tcagcaatca
    49621 gcgggtaata actgcctggt tcgtcatcgg aagtcgtaaa tagcgtgtcg tacagctgct
    49681 cggtgcgtgc gcccgggttg ccgcgcagtg catagcggtt gaaattatcg aaggtgccga
    49741 gggctgacaa cgttatctgc ccaccttttg gcgcggcggg gttcacataa tcaaaatggt
    49801 tgaaattaaa cgcgtaccgg ggttcgccca gcacggcaaa ggcatagctt tccttgatag
    49861 cctgcgcctg cgcaccaaag gtgaacagag cgataaacag cagcagtatg cgcacaatca
    49921 tctgcaacgg atttcctttt actcatcatt agccgcaatc cggcatgctt tcactatgaa
    49981 taataaggga cgtaagcaca ccttaccact gcggcgtata cggtttcttc agccagcgaa
    50041 caaaatcgtc cagcggtaac gggcgactaa tccagtagcc ttgcatgaaa ttaacgccgc
    50101 gttcgcttag ccatcgcgct tgttccggcg tttcgacccc ttcagcaacc gtcagcatat
    50161 tgaggcgttt cgccagcgtc agcaccgcgt caagtacggg tgaagtgatc gtttccgtac
    50221 cgatggcgtt gataaatcca cggtcaattt tcagataatc gagcgtaaaa cgctcaagat
    50281 agataagcgc gctgtgcccg gtgccgaagt catcaatagc aatttctacg cctaccgagt
    50341 gcagccaggc gaagagttgt gtggcttctt gctctttcag catatcgcgc tcggtaattt
    50401 ccagcacaat ctggaaatgg tgtgcgggta gggaagtgag cagtttctgg atatctgctt
    50461 taaagctttc gctgtgcaga tggtccggcg caatgttaat gccaaatttg acgcctaccg
    50521 gcagcacttt ttctaattct gcggcatcgc gggcaattaa ctcaaacaga tgctgagtca
    50581 gcggcacaat catcttttgc gattcggcaa agttaatgaa ggcatccggg ggaatttctc
    50641 ccgcgacagg atgccgccag cgtagcagta cttccaggcc cgttactcgc aaagcttgtg
    50701 tatccaccac cggttgatac gccacgtaaa attgttcgcg cttgatggcg gtcatgattt
    50761 ctctgccggg gcgcatacgt acgctcatca ggtaatagca gagcaggcca acgacagttc
    50821 cactcatgcc gcccagtaaa aatgcgtacc acacatcgtt ccatgtccag tcatctgcat
    50881 aaagccgaac ggtcagagga atgcccgcaa ttttagtttc acggactggc atgtcggtta
    50941 attcgttaac gttcatcaaa cgtgaagaaa aggtagatag cgcagtattg ccaataatga
    51001 gggcgacgcc atcgtaatct tcctgccgtg aactataaaa gagtgaaggc gtcaggttga
    51061 gattcagagc ggcaaagacg ccgctatttt tcagcaaagg gttgcgatac cagatgacga
    51121 ttgcgggttt gttcggcacc atcggcgtgc cgggtaagat cgccatatcg acatttttat
    51181 taatgtcgag cgccggaatc aattcattga gtggaatgtc catctcaccg gtcgcagatg
    51241 aacagaatgt ttttttatct ttcaccagca caaacgtacg gacattcatg ctaaacgccg
    51301 cgcgggcggt cagttcgggg ttagcctgct ggcaggtatc taaggtcagc ggctggagcc
    51361 ggtcagtagt ggatttcagg tcggcaaaat aggtatcgag atacttttgt acgtcggtaa
    51421 tcagtgtgtc gtatttgact tcgtgcttat gccaggccac taaaaactga aggcaactca
    51481 ccagtatcgc aatcatcacg cctgcaacaa tgcaggtaag caggagctta cgtccagaat
    51541 tgggagcgcg tatgaacatg attccgttaa tttcctgaaa ttacgacaac atttaaaaga
    51601 taacaatgac cggactatag cctggatcaa gacgcggaaa catcattttc tctgatgaat
    51661 gaaaacaaaa aagcactgcc taagcagtgc tttcagttaa ctcgttagga tagccaaggg
    51721 attgcatcca aacggtttat tagctgcggc tgagaacccg gcgtgcttcg ttgtaacgct
    51781 tcttccagta cggttcattc atgctggaaa taataacacc actgctggtg gaagcatgga
    51841 caaactgatt gttgccgata taaataccga catggcgtcc cgttgaaccg gcacggaaca
    51901 gaactaaatc acccgtacgc aaattactgc gggaaacaga tttacccatt tcctgctgtt
    51961 cgtaagtcga acgtggaagt tctaagccaa attgctcacg gaatgtacgc tgtacgaaac
    52021 cagaacaatc gatacctttt ttagtgctgc cgcccagacg ataacgtacg cctttccagt
    52081 cagcatactg atccataatt cgcgatttta cgtcgacatt acgaaccagg ttttcaaatt
    52141 catcctgaga agcttgcagt gatgatgttt cactacccac tacacgtgtc tcaggatgca
    52201 tattctttgc ggtgttattt gcactacatg cagaaagcag aaccgctact gcaatcgcgg
    52261 ggatcccgcg caagatatat ctcaaaatcg gttgagattt gaccatgttg tttgttttcc
    52321 cttgaagtcc ttaacgacaa atatcgttat aaaaaaatgc caagcgacac gagactaatt
    52381 acctgggcat gttgaaacaa ttccttaagg ccaaatctgt ggactaacgc acaaaattat
    52441 atgctgtgag gataatctac cgccgaggca aaacgagttc gagattaccc gattggtgcg
    52501 gtcttggcga gcggttttac atgatttttt ataagaaaaa gtgatacaga aagttaataa
    52561 gcgggattgg tcaattaaag tacgattgag tgaaacgcat gcaatccatt catttactta
    52621 gagaatgatt tttgcgcgcg atggatgaaa gcacggtgcg catcatcagg attatcctca
    52681 ctataaaaat aaacctgatg atgttaatta ctgtgagtta tttgttttgg aaatgtttgt
    52741 tttttcccgg tagtgatttg tcaaaaaagg tgattaatcg atcacttaat ggcgtcagca
    52801 acacccaggg caaaccgatc aatatcacgg tcatcgaacc gacaatgatg tcagtaaacc
    52861 agtgtgcgcc aatcattact ctgggaaacg caaaaaccac aaaaataata agggcgataa
    52921 gacctgcaac tttgccgaaa taacgccaca tgaatgccga aaaaataagc agcatcatgc
    52981 cgtgatcgcc gggaaagcta tctcgtgagg catctttcgt gggaacagag agcagttcgc
    53041 tgacgcggtt aatgtcggta aaagtcaatg ttgggctggc ccgttttaca ggaattaatg
    53101 cctgacccag ctggtttaat accactgcag ttaatagcat gaccagacca ataatcacga
    53161 tacgtcgtct gcctggggcg ttttctttca gccagaaact cagcatcaac atacccatcg
    53221 ccagcagtga acaaccgtcg aaggcgcgat tgttggtcaa tgcaaccagc cacaaaaagg
    53281 ccttactttc gaccagtttc tgattaaaga aataaaaaat atccgcatca atcggcaacc
    53341 agaatccatg attaacggga atataccagg aaagaaacag cgcgaggccg acaatattca
    53401 acaacactat ttgcggcaaa tttttaatca tattttctct aattatctta ctgaaaaacg
    53461 caggcaacct tacgcggtag tcgctaaacg aagcttcaac agcgcgctct gcaaagcatt
    53521 ccagtcagct tcgctgctgg aaatcagctc aatacgactg tccggtggcg caacgttttg
    53581 cgtttcaatg tgcaggtcat cgccctgacg gttgattcgt accagccctt cgggaatacg
    53641 cagcacgcct ttgacgcgtt ccaccggtgc aagtcgcgcc cattccagaa tgccaatggt
    53701 gtcgaatacc gtatcagcgt cgaatatcca gccgcaggcc tgatatcctt gcccgctgtt
    53761 cagactgcga cgccagcgtt gatgctctgg caggcttaac gctgctaacc cttttttcac
    53821 gacatgctga tgagaatgcg cggcgctggc gggcaactcg gctaaattgc gacgcggcaa
    53881 atccagaaga tgaccgtcaa ctttcccatg ctcactgtga attaattgtc gatcgccacc
    53941 attttgctgc caccaacgct gtagcgcttg ctcactttcg ggcgtcgcac ggtcggattt
    54001 attggcgaca atgatgtctg cggcagccag ctggtcacgg aagttttcat tgctggcgct
    54061 tttttcgtcc agcagcaagc gcggatcgag aatgcacaag gtggcgcgca gatctatcca
    54121 cggttcatag actggtgcgg ttaacagatc gaggatctgt ttcggatggc ccagcccggt
    54181 cggctctatc aacaagcggt ctggttttcc ctgacgcagt aaggtattca accctacctg
    54241 catgggtaaa ccattaacgc agcacatgca gccgccgggg atctctttca gcaatgcgcc
    54301 gctatcggcg agcaaagcac catcaattcc gacttcccca aattcattaa ccagtaccgc
    54361 ccatttttcg ttgggatctt tatgggctaa cagatgaaga atcgacgtgg ttttcccgct
    54421 gccgagaaaa ccggtgatga ggttggtcct ggtcacaacg gctccgcaat actctggtaa
    54481 gttaactgag cgttaatcct ggctaaaaaa ggcagaaaag agaaggggag agcggacgaa
    54541 ggtgagcttc atccgcttta accgcagaaa tcgttaaatt ttgagggtgt ttaatagcgc
    54601 ctgatgtgcg ccgaattgta cgatttgttg ccaggcttgt tcgatggcct gcacaaaatg
    54661 cgggttatct ggcagatcat caccgaaaac ttcacgcagg gaaagcaggg cggttacgcg
    54721 ttgttcactg ctgctgcccg caacaagttc gcgaatttta tcgctaagcg gatcgcgaac
    54781 atcaatggca tttccggcat catcaacgcc gctgacgtaa cgcatccagc cagcaacgcc
    54841 taatgccagc aacgaccagt ccgtttcgca ccccagatgt atgcgaatac ctgccagcat
    54901 acgttgcggt aatttctggc taccatccat tgcgatttgc caggtcttat gtttcagcgc
    54961 cggattagca aaacgtgcaa ttaacttgtc cgcatattgt gttaaatcga catctttaat
    55021 ttgtagtgtc ggcgcttgct cattcagcat taatgttctg gcggcatggc gaaatgcgcg
    55081 atcctgcatg caatcactga tatgggcgaa tcctgaaagg taacccagat aagcgagaaa
    55141 agagtggctg ccattaagca tacgcagttt catctcttcc catggcagga catcattcac
    55201 catttgtaca cctgcgactt cccaggcagg acgcccagcg acgaagttat cttccactac
    55261 ccactggata aacggttcgc agctaatcgc gcagggatca tttaccccca gatgctggct
    55321 gatttctgcc agtgattcgt cggttgcagc cggaacaatg cggtcgacca tggttcccgg
    55381 aaaactgacg tgttctttta tccacccggc gagttctggc gaacgttttt ctgccattcc
    55441 cagcaccgcg tttttcacca catggccatt gtcgggaata ttgtcgcagg agagcacggt
    55501 aaacggtgta aggccgcgct cacggcggcg tttcagtgct tcgacgagaa tacccggtgc
    55561 ggagtgaggt tcttcagggg tttgtagatc gtgaataatc cgcggattac tggtgtcgag
    55621 tgcaccggtg gccgggtcaa tacaatagcc tttttcggta atcgtcaggg aaacaattgc
    55681 cacctgtggc tcgcaaaatt tctcaataat tgccgctaag gaatccagtt ttgcattaag
    55741 gcattcgtga acggcaccga caattatcac ctgattgccg tccgcacctt tttccagcac
    55801 ggtatataaa tggttctgtg cgcggagctg gctcatcagt tgatcaccgc tgaacaagct
    55861 gatttcacag atcccccagt cgccgccctg ggcattcatc acacgatcgg tcagtaacgc
    55921 ctgatgagcg cggtgaaagg cgccaaagcc aaaatgaacg atacgtgatt gcaactgctg
    55981 gcgatcgtag cgtggagcgt gtacatgatg cgggagcgta acggaggcaa ttgtcttcat
    56041 aggagtcacg tcttagtaac gataaattaa caatgacagt gtaaagttat atgacagcaa
    56101 ttgaaattgg tctggattgt taatgcgatg aagtgtgagg gcgatcaatc aacgagtgaa
    56161 aattgagggc gtaaggtgtt caggaagcgc aaaatagaag attggtataa taaattaaaa
    56221 aagggacagc ctgagctatc ccttttctgc atgcggctga agttagtcag cacgccccat
    56281 ataacggcgt tcttcgatat ggatacgaat tttttcgccc gggcttaagt attctggtac
    56341 ctgaatcacc agaccagtgc tcaatgtcgc cggtttgtta cgggcgctgg cagatgcccc
    56401 tttgatgcct ggtgcggttt caacgatttc cagatcaacg gtctgcggca gctcaagcgc
    56461 cagcagttga ccgtcccagg tcagcacctg catgtccggc atgccgccct ctggcataaa
    56521 cagcaactct tcttcaatct gatctttggt gaaggtatac ggggtatagt cttctttatc
    56581 cataaagaca tattcgttgc catcgacata ggagaagtca acgtaacggc gggtcagcgt
    56641 cacggtgtca acgatatcat cacctttgaa acgctcttct actttcagcc cggtacggac
    56701 atcagaaaaa cgcattttgt acagcgtagc ggcaccgcgg gcagtgggcg actgaatatc
    56761 aatatcctta accagcagca gtttgccgtt gtaattcagt accatacctt ttttaatttc
    56821 gttcgctctt ggcatcgaaa aattcctgta gtcgaaaatg tcaaaaatat cgcgacaaag
    56881 tactcgcgac gggcctttcg ggcaagtggt attcgcactt ttgctggtgc aaaaaaggtg
    56941 gtactgtgcg cgctcatcaa tccggtggtt aaccttaaga gaacaacgta tgaaatgccg
    57001 tccgggttgc ggggcgtgtt gcactgcccc ttcaatttcc agccctattc ccggtatgcc
    57061 agatggcaag cccgccaata cgccctgcat tcagcttgat gaacagcaac gctgtaaaat
    57121 tttcacctcg ccactgcgac cgaaagtctg tgcaggctta caagccagcg ctgaaatgtg
    57181 cggtaactcg cgtcagcagg ccatgacctg gcttatcgat ctggaaatgc tgaccgcgcc
    57241 ttaaacatct ttaatccgca gtaagcaaaa cagagtggcg ataatcatca ccatcgcaaa
    57301 ccagaacaca gcgtgataat tccagatctc ggcgacgatg cccgccactg atcctgcgat
    57361 gatccagccc acgcgcgacg tgttggtata gagcgtggtg gctgaacccg cctgaccggg
    57421 catcagatcc tgaaaataga gcatcccgat gccgcccaga atgccaataa aaatagcatt
    57481 tagcagctgc aagcccaaca gaatgacagg tgaatgcgcc atcagcattc ctgcgtaaaa
    57541 acagacgcca cccacggcag caacgcgcat taagaaacgc ttacccagac gtttggcgaa
    57601 atatccggca atcaacatcg tcgggatttc cagcccggcg gcggtcccca tcatcacacc
    57661 ggccagtttc tcgggaagat gcagttcgtt gataataaat agcggcatgt tgatgatgta
    57721 caggctgttc gagccccaca tcaatgtaca aatgacaaac agcagcagcg tatcgcgacg
    57781 gttacggcgc ggcgcttcga tcgtgccggt cgccagcgga agctcttttt gcatcgacgg
    57841 taaaaacagc cacaccatca caccgcaaac aataaacgct accgctgcgc tcagatacat
    57901 taccgtaaag ctgaaaccca tcgctaaggc ataagccagc ggtgggccaa tgacccatgc
    57961 cagtgaaacc tgagcgcgta aaaaagagct gaacatcacc gcctcacgtc cggttttgtc
    58021 ggcatgttca cgggcaaggg caaacatttg cgggttagcg gtcgagccaa agctgctaag
    58081 aaagacgcca acgaatagca aaacaaagta gttgcgattc caggcaaaaa gggtgcaggc
    58141 cagcacgcct aacaggcagc aaaagacaat cagcgatttg cgatcgccgc gcttatcaga
    58201 gcgcccggcg agaaactgac ttaccagaat cccaatgaca gcgctgccgg taaagaagaa
    58261 tcccaccatc gccggacgag catgtacttc atcagtaaga aaaatactga gtgtcggggt
    58321 ttgcagagcg cccgcaatac cggtgagaaa ggcaacgatt aaaaacgccg tcgaggtcag
    58381 gtcaaacgat ttcgcgctgg agactgcggg ggagttatgc atgctggtcg atcactggaa
    58441 gaggaagacg cggagtttac gctgcttgtc agaaaataaa cagacagcga aatcaaaagc
    58501 gccacgaata atcaaaatgc catttcactg ttgctgattg gctgctgacg ctgctgaaat
    58561 gaaattgctg ataacggatt ttcccatcag caattaggaa aaatggcaaa aaattgtgca
    58621 gcacatcaaa cttttgctca taactttacg gctttccttg cgtgctgaaa cagaagtatt
    58681 atgctttctt gaaacgtttc agcgcgatct tgtctttaac cctaagccag gttggcgctt
    58741 tttttctcat agaggctgaa tcgtttcaat tcagcaagag aggagaacta tgttccagtt
    58801 atccgtacag gacatccatc cgggcgaaaa ggccggagac aaagaagagg cgattcgcca
    58861 ggtcgctgcg gcgctggtgc aggccggtaa tgtagcagaa ggctacgtca atggcatgct
    58921 ggcgcgcgaa cagcaaacct caacgttcct cggcaatggt attgctattc cacacggcac
    58981 taccgacacc cgcgatcagg tgctgaaaac cggcgttcag gtatttcagt tcccggaagg
    59041 cgtcacctgg ggtgacggtc aggtagcgta cgtggcaatc ggtattgctg ccagctcgga
    59101 tgaacatctg ggcctgctac gccagctgac ccacgtactg agcgatgatt ccgttgctga
    59161 acaactgaag tcagcaacaa cagcagaaga acttcgcgca ttactgatgg gcgaaaagca
    59221 gagtgagcag ctgaagctcg acaacgaaat gctgacgctg gatatcgtcg ccagcgatct
    59281 gctgactctt caggcgctga acgctgcgcg tctgaaagag gcgagggcag ttgacgccac
    59341 tttcgtcacc aaagccatca atgaacaacc gctgaacctc ggacagggta tctggctgag
    59401 cgatagcgcc gaaggcaatc tgcgtagcgc gattgcggta agccgtgcgg caaatgcttt
    59461 tgatgtggac ggcgaaacgg cagccatgct ggtgagtgtg gcgatgaatg acgatcagcc
    59521 catcgcggtt cttaagcgtc tcgctgattt attgctcgac aataaagctg accgcttgct
    59581 gaaagcggat gcggcaacgt tgctggcgct gctgaccagc gatgatgcgc cgaccgacga
    59641 cgtgttaagc gcggagtttg tggtgcgcaa tgaacacggc ctgcatgctc gtccaggtac
    59701 catgctggtc aataccatta aacaatttaa cagtgatatt accgtgacaa accttgatgg
    59761 taccggcaaa ccggcaaacg gacgtagtct gatgaaagtt gtggcacttg gcgttaagaa
    59821 aggtcatcgc ctacgcttta ccgcccaggg tgcagatgct gaacaggcgc tgaaagcaat
    59881 cggcgacgct atcgctgctg gtcttgggga gggcgcataa tgagcagacg tgttgctact
    59941 atcaccctta atccggctta tgaccttgtt ggtttctgcc cggaaattga acgcggcgaa
    60001 gtgaacctgg tgaaaaccac cggtctgcat gcggcgggta aaggcatcaa cgtggccaaa
    60061 gtattaaaag acctgggaat tgatgtcacc gttggcggct tcctgggtaa agacaatcag
    60121 gatggttttc agcaactgtt cagcgagctg ggcattgcca accgtttcca ggttgtacag
    60181 gggcgcaccc gaattaacgt taagctgacg gaaaaagacg gcgaagtgac cgacttcaac
    60241 ttctcgggtt ttgaagtcac ccccgccgac tgggaacgct ttgtgactga ttctctgagc
    60301 tggctcggtc agttcgatat ggtctgtgtc agcggaagct taccgtcagg cgtcagcccg
    60361 gaagcgttca ccgactggat gactcgcctg cgtagtcagt gtccttgcat tatctttgat
    60421 agtagccgtg aagcgttagt agcaggtttg aaagcggcac cgtggctggt gaaacctaac
    60481 cgccgcgagt tggaaatctg ggcaggccgt aaactgcctg aaatgaaaga tgtgattgaa
    60541 gctgcacatg cgctacgtga acaaggtatt gcgcatgttg ttatttcact gggtgccgaa
    60601 ggcgcgcttt gggttaatgc ctccggcgaa tggatcgcca aaccaccgtc agtcgatgtc
    60661 gtaagcaccg ttggcgcagg ggattctatg gttggtggcc tgatttatgg cttgctgatg
    60721 cgtgaatcca gtgaacacac actgcgtctg gcgacagctg ttgcagccct ggcggtaagt
    60781 caaagcaatg tgggtattac cgatcgtccg cagttggccg caatgatggc gcgcgtcgac
    60841 ttacaacctt ttaactgaca gcaggagagg cataatgaaa acgctgctga ttattgacgc
    60901 taatctcggt caggcacgcg cctatatggc gaagaccctg ctgggcgcgg cggcgcgaaa
    60961 agcaaaactg gaaatcatcg acaatccgaa cgacgcagaa atggcgattg ttctcggtga
    61021 ttccatcccg aatgacagcg cgctgaacgg taaaaatgtc tggctgggtg atatttcccg
    61081 ggcagttgcg caccctgagc tgttcctgag tgaagccaaa ggccatgcga aaccttacac
    61141 tgcgccggtc actgcgacag caccggttgc cgccagcggt ccgaaacgcg tagttgcggt
    61201 gactgcttgc ccgactggcg tagcacacac ctttatggcg gctgaagcca ttgaaaccga
    61261 agcgaaaaaa cgtggctggt gggtgaaagt tgaaacccgt ggttctgttg gcgcgggtaa
    61321 tgcaatcact cccgaggaag tagccgcagc ggatctggtg attgtggcgg cagatatcga
    61381 agtggatctg gcgaaatttg ctggtaaacc gatgtatcgt acctctaccg gtctggcgct
    61441 gaagaaaacc gcgcaggaac tggataaagc ggttgctgaa gcaacgccgt atgaaccggc
    61501 gggcaaaact caaacggcga ccactgaagg taagaaagag agtgcaggcg cttatcgtca
    61561 cttgctaacg ggcgtctctt acatgctgcc gatggtcgtt gctggtggtc tgtgtatcgc
    61621 gctttctttt gcttttggta tcgaagcgtt taaagagccg ggtacgttgg cagcggcgct
    61681 gatgcagatt ggtggtggtt cagcctttgc gctgatggtg ccggtactgg caggttatat
    61741 tgccttttcc attgccgatc gtccgggcct cacgccgggt ctgattggcg gtatgctggc
    61801 ggtcagcacc ggttctggct tcattggtgg tattattgcg ggcttcctgg ctggttacat
    61861 tgcgaagtta atcagtacgc aattgaaact gccacagagt atggaggcgc tgaaaccgat
    61921 cctgatcatt ccgctaattt ccagtctggt ggtcggtctg gcgatgatct acctgatcgg
    61981 taaaccggtt gctggcattc tcgaagggtt gactcactgg ctgcagacca tggggactgc
    62041 gaatgcggtt ctgctggggg cgatcctcgg tggcatgatg tgtactgaca tgggcggtcc
    62101 ggtaaataaa gcagcgtacg cattcggtgt gggtctgctg agtactcaaa cctatggccc
    62161 gatggcggcg attatggcgg caggtatggt gccaccgctg gcaatgggcc tggcaacaat
    62221 ggtggcgcgt cgcaaattcg acaaagcgca gcaggaaggt ggcaaagccg ctctggtact
    62281 gggactgtgc tttatttcgg aaggtgcaat tccgtttgct gctcgtgatc cgatgcgtgt
    62341 gctgccgtgc tgtatcgtgg gtggggcgct gactggcgca atctcaatgg cgattggtgc
    62401 gaaactgatg gcaccgcacg gtggtctgtt tgttctgctg atccctggcg ctattacgcc
    62461 ggtattgggt tacctggtag caattattgc cggtacgctg gtggcgggtt tggcctatgc
    62521 cttcctgaaa cgtccggaag tggacgcagt agcgaaagca gcgtaataaa aggtgtgtta
    62581 cagggcagaa atttcctgcc ctgtatcatt ggatgagcgc aaagggaatg accggtttgt
    62641 aaatgtaatt ttatgaattt aaatggtttt atctttcagt agaaacctga aacgttcatc
    62701 aaacactaag gttatttcct caagggcaga ttattttctg ccctttttta gtgttcctgt
    62761 tctgtgcatc ccgtcacaaa ttcctcgctt ttgtaattca ggtatttaat cgcattttgt
    62821 gagcctgctc aaatctgccc attttgcctc tctggcggta atttacttta cgtaaaacat
    62881 gcatactata agcacatgtt taaatatgaa cacatgttta aaccgtcttt gcagtatcta
    62941 tattcttgtg gattgacagg gttggtaatt ttttaccaga ggacgtgcta tgcgcgaaaa
    63001 ggattatgtc gtaattatag gttcggcgaa tattgatgtc gccggatatt cacatgaatc
    63061 attaaattat gcggattcaa atccaggtaa aataaaattt acgcctggtg gagtagggcg
    63121 caatattgca caaaacctgg cgttgctggg taacaaagcc tggctactga gcgcagtagg
    63181 cagtgatttt tatggtcaat cgctgctaac gcaaaccaat caatctggcg tttatgtcga
    63241 taaatgcctg attgtgccgg gagaaaatac gtctagttat ttatcattac tcgataatac
    63301 cggtgaaatg ctggttgcta taaatgacat gaatattagc aacgctatta cagctgaata
    63361 tctcgcacag caccgtgaat ttattcagag ggcaaaggtc attgtcgcag actgtaatat
    63421 cagtgaagag gcactggcat ggattctgga taatgccgcc aacgtacccg tatttgtcga
    63481 tccggtttca gcgtggaaat gtgtcaaagt gcgcgaccgt ctaaatcaga tccacactct
    63541 caagccaaac cgccttgaag cggaaaccct gagtgggatt gcgctgtcag ggcgtgacga
    63601 tgtggcaaaa gttgctgcct ggttccatca acatggcctg aaccgactgg tattgagcat
    63661 gggcggcgat ggcgtttatt acagcgatat cagcggtgaa aatggctggt ctgcgccgat
    63721 caaaaccaat gttattaatg ttaccggagc gggcgatgcc atgatggcgg gacttgcttc
    63781 gtgttgggta gacggaatgc cgtttgccga atctgttcgt ttcgcacagg gatgttcgtc
    63841 aatggcgctc tcctgtgaat acaccaataa ccccgattta tcgattgcca acgttatatc
    63901 gttagtggag aacgcagaat gtctgaatta aaaatttccc ctgaattatt acaaatttcc
    63961 ccggaagtgc aggacgcttt aaaaaacaaa aaaccggttg tggcgctgga atcgaccatt
    64021 atttctcacg ggatgccgtt cccacaaaat gcccagaccg caattgaagt agaagaaact
    64081 attcgtaaac agggcgcagt acctgccact atcgccatta ttggcggcgt gatgaaagtg
    64141 ggtttaagca aagaagaaat tgaattactg ggtcgtgaag ggcataacgt gaccaaagtt
    64201 agtcgtcgcg atttaccttt tgttgttgcc gccggaaaaa atggcgcaac cactgtggct
    64261 tcaacgatga ttattgcggc gcttgccgga attaaagtat ttgccaccgg gggaattggt
    64321 ggtgtgcatc gcggggcgga acataccttc gatatttctg ccgatttgca agaactggca
    64381 aatactaatg tcaccgttgt ttgtgccggg gcgaaatcta ttctcgattt aggattaacc
    64441 actgagtatt tagaaacctt cggtgtgccg ttaattggct atcagactaa agcgctgcct
    64501 gcgtttttct gccgtaccag ctcgtttgac gtcagcattc gtctcgacag cgccagtgaa
    64561 attgcccgtg caatggcggt gaaatggcaa agcgggctga acggtggcct cgtggtagcg
    64621 aacccgatcc cggaacagtt tgcgatgccg gaggaatcta tcaatgcagc catagatcaa
    64681 gccgtcgccg aagccgaaga gcagggcgtt attggtaaag aaagtacacc gttcctgctg
    64741 gcgcgcgttg ctgagctgac cggcggtgac agcctgaaat ccaatatcca gctggtgttc
    64801 aacaacgcca ttctggcgag tgaaattgcc aaagaatacc agcgtctcgc gggttaattt
    64861 ctgacgggca gaaagccgtc gcccgtactc atcaagcata ccaaaacctg gcgctgacgc
    64921 cgggtttact ggcatgaagg gaaaatcatt atggatataa tgagaagtgt tgtggggatg
    64981 gtggtgttac tggcaatagc atttctgttg tcagtgaata aaaagagcat cagtttgcgc
    65041 acggttggag ccgcactgct gctgcaaatc gctattggtg gcatcatgct ctacttccca
    65101 ccgggaaagt gggcagtaga acaggcggca ttaggcgttc ataaagtgat gtcttacagt
    65161 gatgccggta gcgccttcat ttttggttcg ctggttgggc cgaaaatgga tgtcctgttt
    65221 gacggtgcgg gttttatctt cgcctttcgc gtacttccgg cgattatttt cgttactgcg
    65281 ctcatcagtc tgctgtacta cattggcgtg atggggctgc tgattcgcat ccttggcagc
    65341 attttccaga aagctcttaa catcagcaaa atcgaatctt ttgtcgcagt cacaactatt
    65401 ttcctcgggc aaaatgagat cccggcgatc gttaaaccgt ttatcgatcg catgaatcgc
    65461 aacgagttgt ttaccgcaat ttgtagcggg atggcgtcca ttgctggttc gatgatgatt
    65521 ggttatgccg gaatgggcgt accaattgac tacctgttag cggcatcgct gatggcgatc
    65581 ccaggtggta ttttgtttgc acgtattctt agcccggcca ccgagccttc acaggtcaca
    65641 tttgaaaatc tgtcgttcag cgaaacgccg ccaaaaagct ttatcgaagc ggcggcgagc
    65701 ggtgcgatga ccgggctgaa aatcgccgct ggtgtagcga cggtggtaat ggcgtttgtc
    65761 gcaattattg cgctgatcaa cggcattatc ggcggaattg gtggctggtt tggtttcgcc
    65821 aatgcctctc tggaaagtat ttttggctat gtgctggcac cgctggcgtg gatcatgggt
    65881 gtggactgga gtgatgccaa tcttgcgggt agcctgattg ggcagaaact ggcgattaat
    65941 gagtttgttg cttatctcaa tttctcgccc tatctgcaaa cgagcggcac gctggatgtc
    66001 aagaccattg ccattatctc gttcgccctc tgtgggtttg caaactttgg ttctatcggt
    66061 gttgtcgttg gcgcattttc ggctatttcg ccaaaacgtg ctccagaaat cgcccagctt
    66121 ggtttacggg cgctggcagc agcaacgctt tccaacctga tgagtgcgac tattgccggg
    66181 ttctttattg gtctggcgta atgctcgatt tgtagaccgg ataaaacgta ttaagcgttg
    66241 catccggcaa tcgcgctatt gcaaataatt tttactgcat catcccggag aatttattct
    66301 ccgggtccat ctccagcgcc agtcctgaca actgctttct gtttttaatg agataccctt
    66361 tcttgctttt agttaataaa ccgtcgtgaa tgaattgcgc gagaacatat aaaagatgtc
    66421 gataagaaac gcctaaatac tctgccgctt gcgtatgctt ttcgtgataa agatcacctt
    66481 cctgcgagag taatataaaa gctgccaggc gattaactaa cggaaatgat tgattctgag
    66541 ttaaagaaac aatattacga taatttttat gacttaaggt gacgcagagt tttcgtaaaa
    66601 atagcgtgtc gtttaataac agcgggcggt aatgtttcat agggagcgca aggcaccaac
    66661 actcttcaat agcctgcacc gcacgcggtt catggtcttt gtcgattaac tcaatctcgc
    66721 caataaaaca gggggcggca aagaaatcga tcagcgacac gcgaccatta gctagcgtgg
    66781 cgtaaagcct ggcgcggcct cgcgtcaggt aaaacagcca ggacggctgt tgcccttcct
    66841 gcacaatgta gtcacgcgct aaaaaatgaa acagccgcgt atcggctgaa acatccgtta
    66901 aaaagcaatc cttaaacgcg gattcactca tcaattgctg cttaagatca ttattgtgga
    66961 tttctttcac gatgtttatc cgctatgaga tttctcatat ttagcatacg tacgcggttg
    67021 gtaagattca atcatcggcc cggtcgaatt ttctttgctg tagaaaaaat aacgcaactg
    67081 gaaacagagg aaataaacaa tggaaaagag aaaaattatt ctggattgtg atccgggtca
    67141 tgatgatgct attgcaatga tgatggcagc gaaacatccg gcaatagatt tattaggcat
    67201 cactattgta gcgggtaatc agacgcttga taaaacatta attaatggcc tgaatgtttg
    67261 ccagaaactg gagattaatg ttccggttta tgcggggatg ccgcaaccca ttatgcgtaa
    67321 acaaatcgtt gccgataata ttcacggtga aaccggactg gatggcccgg tattcgagcc
    67381 gctgacccgc caggcagaaa gtacccacgc ggtgaaatac atcattgata ccctgatggc
    67441 aagcgatggc gatatcactc tggtgccggt tggtccgctt tcaaatatcg cggtggcaat
    67501 gcgtatgcaa cccgcgatcc tgcccaaaat ccgtgaaatt gtgctaatgg gcggcgctta
    67561 cggtacaggc aacttcacgc catctgccga gttcaacatc tttgctgatc cggaagcagc
    67621 ccgcgtggtg ttcacctccg gcgttccatt agtgatgatg ggcctcgatc tcaccaacca
    67681 gaccgtttgc accccggacg tgattgcacg gatggaaagg gcaggcggcc ctgccggaga
    67741 gctgttcagc gacatcatga acttcactct caaaacgcag ttcgaaaact acggcctggc
    67801 tggcggcccg gtgcacgacg ccacctgcat cggttatctg attaaccctg atggcattaa
    67861 aacacaggag atgtacgtcg aagtggacgt caacagtggc ccttgctatg ggcgtaccgt
    67921 ctgcgacgag ctgggcgttc ttggcaagcc cgctaatacc aaagtcggca tcactattga
    67981 taccgactgg ttctggggct tagtcgaaga gtgcgtgcgc ggctacatca aaacccatta
    68041 agtgttgata acaagccggg tcagtatcgc aagatccaag cccggctatt tctgatgggc
    68101 agaaagccgt cgcccaatat gacatgaaga gataataact atggatgtca tgagaagtgt
    68161 tctgggaatg gtggtattgc tggcaattgc atttttgctg tcagtaaaca agaagaagat
    68221 cagcctgcgt accgttggcg cggcgttagt gttacaggtt gtgattggcg ggattatgct
    68281 ttggttaccg ccagggcgtt gggtcgctga aaaagtcgct tttggcgtgc ataaagtgat
    68341 ggcgtacagc gacgcgggta gcgcatttat cttcggttcg ctggtcgggc cgaaaatgga
    68401 cacgctgttt gatggcgcag gatttatctt tggtttcagg gtattaccgg caattatctt
    68461 cgtcactgca ctggtgagta ttctctacta catcggtgtg atggggattt taattcgcat
    68521 tctcggcggt atcttccaga aagcgttaaa tatcagcaag attgagtcat tcgtcgcggt
    68581 caccaccatt ttcctcgggc aaaacgaaat tccggcgatc gtcaaaccct ttatcgatcg
    68641 tctgaatcgc aatgaattat ttacagcgat ttgtagtggc atggcctcga ttgctggttc
    68701 gacaatgatt ggttacgccg ccctgggcgt acctgtggaa tatttgctgg cggcatcgtt
    68761 aatggcgatc ccaggcggga tcttgtttgc ccgcctgtta agcccggcta cggaatcttc
    68821 gcaggtttcc tttaataacc tctctttcac cgaaacaccg ccaaaaagca ttattgaagc
    68881 cgctgcgaca ggggcaatga ccgggctgaa aatcgccgcc ggtgtagcga cagttgttat
    68941 ggcatttgtc gccatcattg cgttaattaa tggtattatc ggcggcgttg gcggctggtt
    69001 tggttttgca catgcctcgc tggagtccat tttaggttac ctgttggccc cattggcgtg
    69061 ggtgatgggg gttgactgga gtgatgcaaa tcttgccggg agtttgattg ggcagaagct
    69121 ggcgatcaat gaatttgtcg cttatctcaa tttctcgcca tatctgcaaa cgggtggcac
    69181 tctggatgct aaaaccgtgg cgattatttc tttcgcgttg tgcggtttcg ctaactttgg
    69241 ttctatcggg gtggtggtgg gggcgttttc tgcggttgcg ccacaccgtg cgccggaaat
    69301 cgcccaactt ggtttacgcg cgctggcggc ggcgacactt tctaacctga tgagtgctac
    69361 tattgcagga ttctttattg gtttagcgta gtgcgcaatt tatgagccgg ataagatgcg
    69421 gtcaagcgtc gaatccggca acattgttac accattggca ctaatgaaag cgcgttatcg
    69481 gcagacaggg tagggttgtt taagctgccg ctggcgcgcg aaattgccgc gcaggctacc
    69541 gcaaaacggg cgctgtcgcg gaaactgtat ccttcaagaa agctatatac caggcccgcc
    69601 ataaaaccat cgtcagcacc aaaactgtct actgtcgtat gcgctggcgc ggtcagcaaa
    69661 aattgttctc catccttatc gctgcaaaat acagattcat ctttcagata aacaaaaatg
    69721 cgtttaacac cttgttgatg cagcgaattt acagctctga tgcgatcgtt gtcgtcttta
    69781 atcggttgcc cccacaaaat ttccagttca ttttgtgttg gtttcagagt gtggatccgg
    69841 ctgtaccagt tttttacttt gttcgcttta aattcggaaa cggtatcgac aaacatcgga
    69901 atttcatcag caatggtaaa gacccactcc agggcttcag gtgtgagatt acaatcagcc
    69961 agcaccacac cagcatggcg aatcaagtcc cgtgaagtat tgagcagttg aggcgttagc
    70021 tgttgcagaa tatgtgtgtc attgattgcc aggatagttt cttcctgctt attagcgata
    70081 gcgagataag ttgcagtgct gtgtccatgc agacgaatgc agtttgaaac gttcacgccc
    70141 gcgcggcgcg tttcttccag taatgtctcg ccgtaaaaat cgttgccaat agctgatatt
    70201 aaatgcacat cccgaccaag cagagccagg ttatgcgcga tattacgtcc gacgccgcct
    70261 gcggaacagt gaacagaacc tggatgagag gctgcttgcg ggtaacggat atccgccatt
    70321 ccgcgaatat ccatattgat tgcacccaca accacacagt aatcctgctc ggtaaggata
    70381 tatcctttgc ctttaatcaa acccttgcgc atcaaatcca taatatgagc ggcaacacgt
    70441 gagcggctga tttgcagaat atcggcgatt tcattctgtt gaatcagcgg gttacgccgt
    70501 aaaattttaa gaatctgctt ttccctgtcg ttcatcgatc aggccaccgc tttttcagtt
    70561 tgttgcgctt tcagccaggc gatctcttct gcccagatat ccgggttgat ggtttcaagg
    70621 atcagcggaa tgccgtcgaa acggtcgtcc tgcatgatcc agcggaacgc atcatgaccg
    70681 atattgcctt caccgaggct atgatggcgg tcaacgcggc tgccaaaggt gcttttcgca
    70741 tcgttaaggt gcatcccgcg cagatactta aagccaacaa tacgggcaaa atccgcgaac
    70801 gttttctcgc attcggctgg agtacgcaaa tcatacccgg cagcgaaagc atggcaggta
    70861 tcaatgcaga cgccgacacg ggatttatct tccacgccgt cgataatcgc cgcgagatgt
    70921 tcgaatttaa accctaagtt actgccctga ccggcggtgt tttcaatcac cgctgttaca
    70981 ccttgagttt tatccagcgc aatgttgatg gattcggcaa tacgcgcaag gcaatcctct
    71041 tctgaaatct gcatcagatg gctgccaggg tggaagttga gcaaagaaag ccccagttgt
    71101 tcgcaacgct gcatttcatc tataaaggca tcgcgcgatt tttccagagc ttcagtgacc
    71161 ggatgtccga ggttaatcag atagctgtcg tggggaagaa tttgcgccga tgtgtagtga
    71221 tatttttcac aggccgcttt gaattcatcg atggtttgcg tcgtgagcgg tgcggcacgc
    71281 cactgacgtt ggtttttggt gaacaaggca aacgcggttg cgtcgatttc ggcggcgcga
    71341 attgcggcat ttgccagacc gccagcagca ctaacgtgcg ctccaatgta tttcatgcga
    71401 ggactcctgt taaacccgct ggaggaaaac ggtaatgata gcgggttaac aggagcaaga
    71461 tgtagtggtt tatgcgatga cgctttgaat cacatagtta atcgcaccac caccaacaat
    71521 cagccaggca aacagtacca gtgccatcag cagaggtttc gccccggctt ttttcagcgc
    71581 gctgacgtga gtggtcagac ccagcgccgc catcgccatt gccagcagga aggtatccag
    71641 cgttaccagc atgttcacca cgctctgcgg taacaggtgg aacgagttaa agatggcaac
    71701 gacgatgaac aagatggcaa accacggaat agtgattttg cttttctcgc cgctgttcgc
    71761 cccagacagc tgtttaacac gcgccgccag caggatgagg aacggagcca gcatcatcac
    71821 gcgcagcatt ttggaaataa ctgctgcgtt ttccgcatcc gggctgatgg catgacctgc
    71881 cgccaccacc tgcgccactt cgtgcacagt agaaccaatg tagataccga aagtttccgg
    71941 actaaaccat tgagacatca gcggatatat cgccgggtag aggaaaatag cgacggtccc
    72001 gaagataaca acggttgcaa cagccacggt tactttactg gcttccgctt tcactactgg
    72061 ctcagtcgcc agtaccgcgg cagcaccaca gatactgcta ccggcaccga tcaaccagct
    72121 ggtgtgctta tccagaccaa acactttctg ccccaggaag caagccagca ggaaggtact
    72181 ggacagcgtc agcacgtcaa tgatgatccc actgataccg acatcggcaa tttgcgagaa
    72241 cgtcagacgg aagccataaa gaatgatacc cagacgtaat aaatattgct tggcaaacag
    72301 cacaccaccg tcacagcttt tccagatgtg cggatagatg gtgttgccta aaaccatccc
    72361 caacaagatt gcgagggtga gggcactaaa cccggcaccc gcaaccgcgg gaatggaacc
    72421 accccacagg gcgaccccgg tgataactgc actcagggct aaccccggaa taaaatgcca
    72481 cagtgtacga tgttgtttct gtaaggtgat attcgtcata accctctcct ttaaccgggc
    72541 ataaggttac gactaactgg tttaaaaata aaattgatta tatatttata attaatcttt
    72601 ataagtggta agcgactatg cacatcaccc tccggcagtt ggaagttttt gcagaagtat
    72661 tgaaaagtgg atcaaccacc caggcgtcgg tgatgctggc gttgtcgcaa tcagcagtga
    72721 gcgcagcctt gaccgacctg gaagggcagc ttggcgtgca actgtttgat cgcgtgggga
    72781 aaagactggt tgttaatgaa cacgggcggc tgctctatcc gcgtgcgttg gcattgcttg
    72841 aacaggcggt tgaaatcgaa caactgtttc gcgaagacaa cggcgcgatt cgtatctatg
    72901 ccagtagtac catcggtaac tacattctgc ctgcagttat cgcccgttat cgccatgatt
    72961 atccgcagtt gccgattgaa cttagcgttg ggaacagcca ggacgtgatg caagcggtgc
    73021 tggatttccg cgttgatatt ggttttattg aaggaccgtg ccacagcact gaaattattt
    73081 ctgaaccgtg gctggaagac gagctggtgg ttttcgccgc gccgacttcg ccgttggccc
    73141 gtggtccggt caccttagag cagctggccg ctgcgccgtg gatcctgcgt gaacgcggtt
    73201 ccggcacgcg ggagattgtc gattatctat tgctgtcaca tttaccgaag tttgagatgg
    73261 cgatggaatt aggtaactcc gaggcaatca aacatgcggt gcgtcatggg ttgggaatta
    73321 gttgcctgtc gcgacgggtg attgaagatc aattgcaggc aggcacatta agtgaagttg
    73381 cggtccctct gccgcgcctg atgcgtacgt tgtggcgtat acatcatcgg caaaaacacc
    73441 tttccaacgc gctacggcgc tttctggact attgcgatcc cgcgaatgta ccgcgttaag
    73501 ttgctgtaca agaacatgct ggtgctgtgt cgatttcgtg acgcagcgcc ctcagcatgc
    73561 attcgccaga aaagagattg gctgctttac ttataatccc tgggcgatca tgaaggtgtc
    73621 ttataaccgt gtatttctgc cggaaggatt gccaatcgtc tgctacaatc gcgcctcatt
    73681 tttaagatgg atagcatttt tgtatggttt ccgaaactaa aaccacagaa gcgccgggct
    73741 tacgccgtga attaaaggcg cgtcacctga cgatgattgc cattggcggt tccatcggta
    73801 caggtctttt tgttgcctct ggcgcaacga tttctcaggc aggtccgggc ggggcattgc
    73861 tctcgtatat gctgattggc ctgatggttt acttcctgat gaccagtctc ggtgaactgg
    73921 ctgcatatat gccggtttcc ggttcgtttg ccacttacgg tcagaactat gttgaagaag
    73981 gctttggctt cgcgctgggc tggaactact ggtacaactg ggcggtgact atcgccgttg
    74041 acctggttgc agctcagctg gtcatgagct ggtggttccc ggatacaccg ggctggatct
    74101 ggagtgcgtt gttcctcggc gttatcttcc tgctgaacta catctcagtt cgtggctttg
    74161 gtgaagcgga atactggttc tcactgatca aagtcacgac agttattgtc tttatcatcg
    74221 ttggcgtgct gatgattatc ggtatcttca aaggcgcgca gcctgcgggc tggagcaact
    74281 ggacaatcgg cgaagcgccg tttgctggtg gttttgcggc gatgatcggc gtagctatga
    74341 ttgtcggctt ctctttccag ggaaccgagc tgatcggtat tgctgcaggc gagtccgaag
    74401 atccggcgaa aaacattcca cgcgcggtac gtcaggtgtt ctggcgaatc ctgttgttct
    74461 atgtgttcgc gatcctgatt atcagcctga ttattccgta caccgatccg agcctgctgc
    74521 gtaacgatgt taaagacatc agcgttagtc cgttcaccct ggtgttccag cacgcgggtc
    74581 tgctctctgc ggcggcggtg atgaacgcag ttattctgac ggcggtgctg tcagcgggta
    74641 actccggtat gtatgcgtct actcgtatgc tgtacaccct ggcgtgtgac ggtaaagcgc
    74701 cgcgcatttt cgctaaactg tcgcgtggtg gcgtgccgcg taatgcgctg tatgcgacga
    74761 cggtgattgc cggtctgtgc ttcctgacct ccatgtttgg caaccagacg gtatacctgt
    74821 ggctgctgaa cacctccggg atgacgggtt ttatcgcctg gctggggatt gccattagcc
    74881 actatcgctt ccgtcgcggt tacgtattgc agggacacga cattaacgat ctgccgtacc
    74941 gttcaggttt cttcccactg gggccgatct tcgcattcat tctgtgtctg attatcactt
    75001 tgggccagaa ctacgaagcg ttcctgaaag ataccattga ctggggcggc gtagcggcaa
    75061 cgtatattgg tatcccgctg ttcctgatta tttggttcgg ctacaagctg attaaaggaa
    75121 ctcacttcgt acgttacagc gaaatgaagt tcccgcagaa cgataagaaa taagtttcct
    75181 cccttccttg ctaagccctc tcaaccgaga gggctttttc aattccattt ccctgacaaa
    75241 tcatgcggat ataaaattta acatttggat tgataattgt tatcgtttgc attatcgtta
    75301 cgccgcaatc aaaaaaggct gacaaatcag aggctgttcc ggctttctgg gatgatcacc
    75361 tgcatacaaa taagtccacc gcgatgctgc cgtacgcaag gggacgtgaa gaagatgtga
    75421 gcgataaccc attttatttt cgtagttacc tcatggagat atggaatgtt taggttgaac
    75481 cctttcgtac gggtcgggct gtgtttgtcc gctatttctt gtgcatggcc tgtgttagcg
    75541 gtcgatgatg atggcgaaac gatggttgtc actgcatctt ccgttgaaca aaacctcaaa
    75601 gatgcacccg ccagtatcag cgtcattacc caggaagacc tgcagcgaaa accggtacag
    75661 aatctgaagg atgtcctcaa agaagtgcct ggcgtacaac tgacgaacga aggggataac
    75721 cgtaagggcg ttagtattcg tggtctggac agcagctaca ccctgattct cgtcgacggt
    75781 aaacgcgtta actcccgcaa tgccgtcttc cgccacaatg atttcgatct gaactggatc
    75841 ccggtcgatt ccatcgaacg tattgaagtg gttcgtggcc cgatgtcgtc gctatacggc
    75901 tccgatgcgc tcggcggtgt agtgaatatc atcaccaaaa aaatcggtca gaaatggtcg
    75961 ggtaccgtta ccgtcgatac caccattcag gaacatcgcg atcgcggtga tacctataac
    76021 ggtcagttct ttaccagtgg accattaatt gatggtgtgc tgggaatgaa agcttacggc
    76081 agcctggcaa aacgtgaaaa ggatgacccg caaaactcaa cgaccaccga taccggagaa
    76141 acgccgcgta ttgaaggatt ctccagccgc gacggcaatg tcgaatttgc ctagacaccg
    76201 aatcaaaatc acgattttac tgccggatac ggtttcgacc gtcaggatcg tgattccgac
    76261 tcgctggaca aaaaccgcct ggaacgccag aactactccg tcagccataa tgggcgttgg
    76321 gattacggca ccagcgaact gaaatactac ggtgagaaag tcgagaacaa aaaccctggc
    76381 aacagcagcc cgataacttc cgaaagcaat gcggtcgacg gcaaatacac gttgccgctg
    76441 acggcaatta atcagtttct cacggttggc ggtgaatggc gtcacgacaa acttagcgat
    76501 gcggtgaacc tgaccggggg aaccagctcc aaaacgtctg ccagccagta cgcgctgttt
    76561 gtggaagatg aatggcggat cttcgagccg ctggcgctga cgaccggcgt gcgtatggac
    76621 gatcacgaaa cctacggtga acactggagt ccgcgtgcct acctggttta taacgccacc
    76681 gacaccgtaa cggtgaaagg gggctgggcg acggcattta aagcaccttc tctgttgcaa
    76741 cttagccctg actggacgag caattcctgc cgtggcgcat gtaagattgt gggtagcccg
    76801 gatctgaaac cagaaaccag cgaaagttgg gagctggggc tttactacat gggtgaagaa
    76861 ggctggctgg aaggggttga atccagcgtt accgttttcc gtaacgatgt gaaagatcgt
    76921 atcagcatca gccgtacgtc tgacgtcaac gctgcaccgg gctaccaaaa ctttgttggt
    76981 tttgagacgg gcgctaacgg acggcgcata ccggtattta gctactacaa cgttaacaaa
    77041 gctcgtattc agggcgtgga aaccgaactg aaaattccgt tcaacgatga atggaaactg
    77101 tcgatcaact acacctacaa cgatggtcgt gatgtcagca acggcgaaaa caaaccgcta
    77161 tccgatctgc cgttccatac tgctaacggt acgctggact ggaaaccgct ggcgctggaa
    77221 gactggtcat tctatgtttc tggtcactat accgggcaga aacgcgccga cagcgcgacg
    77281 gctaaaacac cgggcggtta taccatctgg aataccggcg cggcctggca ggtgactaaa
    77341 gacgtcaaac tgcgcgcagg cgtgctgaac cttggcgaca aggatctcag tcgtgacgac
    77401 tacagctata acgaagacgg acgtcgttac tttatggcag tggattatcg cttctgatga
    77461 gaagatgccc ggcgaaccgg gcggactttc acttcagtaa atactgcgca tggaagcgca
    77521 ggtgatcctc tataaaagag gcgatgaagt agtaactgtg atcatatccc ggctgaatac
    77581 gcagcgtcat cggccacgct ttctggcgcg cggcttctgc cagtaccgca ggttgcaact
    77641 ggtcggcaag aaactgatca ttatcgccct gatcgataag cgtcgggatc gcatcctgcg
    77701 cgttactggc atacatcagc gcgcaactgt cccattccag ccatgcattt ttgtcctcac
    77761 ctaaatagct gctaaacgct ttgattcccc acgggacgct gcacggattc acaattggcg
    77821 caaaggccga aacgctggtg tatttacccg gatttttcag cgccataatc agcgcaccgt
    77881 gaccacccat tgaatgaccg ctaatggcgc agcggtcgct gacattaaat tgcgactgaa
    77941 ccagcgccgg taattcatcg cgcagataat catacatccg gtaatgcgtc gcccacggcg
    78001 gttgcgtggc gttaagataa aaccccgcgc cctggcctaa atcgtagcca tcatcgttgg
    78061 caacctgttc gccgcgcggg ctggtgtctg gcatcaccag tacaatcccc agttctgccg
    78121 ccacgcgctg ggcacccgcc ttggtggtga agttctcgtc attgcaggtt aatccggaaa
    78181 gccagtacag cactggtggc ggggtgtgat cacgaggggg tgggagaaag atactgaacg
    78241 tcatcgggca gtttaaggta ctggagtcgt gtcgccagcg ttgctgccag ccttcaaaac
    78301 agcggtgctc ttcgagcatt tccatgcgtg gctccttgtt gtgttgtttg caatttcttc
    78361 atcataccgt ttattcaatg tgctgtgagt aactttcact tccgtatttg cataacgatg
    78421 ttttaacatc tgctgatgaa aggcagcggc aattacaata attatcgctg tgaatactgg
    78481 attatgtgcg ccgcctcacg cacaataatc aggctgtaaa tcagcttaat aactttgccc
    78541 ccacgcaggg cggaggcgtc acacctgcag gagaaatcat aaatgccatc actcagtaaa
    78601 gaagcggccc tggttcatga agcgttagtt gcgcgaggac tggaaacacc gctgcgcccg
    78661 cccgtgcatg aaatggataa cgaaacgcgc aaaagcctta ttgctggtca tatgaccgaa
    78721 atcatgcagc tgctgaatct cgacctggct gatgacagtt tgatggaaac gccgcatcgc
    78781 atcgctaaaa tgtatgtcga tgaaattttc tccggtctgg attacgccaa cttcccgaaa
    78841 atcaccctca ttgaaaacaa aatgaaggtc gatgaaatgg tcaccgtgcg cgatatcact
    78901 ctgaccagta cctgtgaaca ccattttgtt accatcgatg gcaaagcgac ggtggcttat
    78961 atcccgaaag attcggtgat cggtctgtca aaaattaacc gtatcgtgca gttctttgcc
    79021 cagcgtccgc aggtgcagga acgtctgacg cagcaaattc ttattgcgct acaaacgctg
    79081 ctgggcacca ataacgtggc tgtctcgatc gacgcggtgc attactgcgt gaaggcgcgt
    79141 ggcatccgcg atgcaaccag tgccacaaca acgacctctc ttggtggatt gttcaaatcc
    79201 agtcagaata cgcgccacga gtttctgcgc gctgtgcgtc atcacaactg attaaaaggc
    79261 aggaaccatg gagcgcaacg tcacgctcga ttttgttcgc ggcgtcgcca ttctggggat
    79321 cctgctatta aacatcagcg cctttgggct accaaaggcg gcttatctca atcccgcctg
    79381 gtacggtgct attacgccgc aggatgcatg gacctgggca tttcttgatc tcatcggcca
    79441 ggtgaaattc ctcacgcttt ttgcgctgct gtttggtgct ggactgcaaa tgttgctgcc
    79501 ccgtggcaga cgctggatcc agtcgcggtt aacgctgtta gtcttattgg gctttattca
    79561 cggtttattg ttctgggacg gcgatattct gctggcttac gggctggtgg gcttaatctg
    79621 ctggcggctg gtgcgcgatg cgccatcggt aaaaagcctg tttaataccg gcgtcatgct
    79681 ttatctggtg gggcttggcg ttttgctgtt attggggctg atttccgaca gccagaccag
    79741 ccgcgcctgg acgccggatg catcggctat tttgtatgaa aaatactgga agcttcacgg
    79801 cggcgttgat gcgatcagta atcgtgccga tggtgttggc aacagtttac tggcactggg
    79861 cgcacagtat ggctggcaac tggctgggat gatgctcatt ggtgcggcgc tgatgcgcag
    79921 cggctggctg aaagggcagt tcagcttacg tcactatcgt cgtactggtt ttgtgctggt
    79981 ggcgattggg gtgaccatta accttcctgc catcgccctg caatggcagc tggactgggc
    80041 gtatcgctgg tgtgccttct tacttcaaat gccgcgggaa ctgagtgcgc cgtttcaggc
    80101 gattggctat gcgtcgctgt tttatggctt ctggccgcaa ttaagccgct ttaagctggt
    80161 gctggcaatc gcctgcgtcg gacggatggc gctgaccaac tatctattgc aaacgctgat
    80221 ttgtaccacg cttttttacc acctcggttt gtttatgcat tttgatcgcc tggagctgct
    80281 ggcgtttgtt attccggtat ggctggcgaa tatcctcttc tctgttatct ggctgcgtta
    80341 cttccgccag gggccggtgg aatggctctg gcgtcagtta actttgcgtg ctgccggaac
    80401 ggcaatatct aaaacatcaa gataacgatc tggatcacat tcgttaacaa aacggctgta
    80461 accgtttcca ttgctgtgac tcgattcacg aagtcctgta ttcagtgctg acaaaatagc
    80521 cgccagcaag cagtcattta ctgcaatctc ataacaggta gtgaatatga tcaccattcg
    80581 tgatgtagcg cgtcaggctg gcgtctctgt ggcaacggtt tcccgggtgc tcaataacag
    80641 cacgctggtc agtgccgaca cgcgtgaagc agtaatgaaa gccgtgagtg agctggatta
    80701 tcggccaaat gccaatgccc aggcgctggc aactcaggtt agcgatacca ttggcgtggt
    80761 ggtgatggac gtttctgatg cttttttcgg cgcgctggta aaagcggtgg atctggtcgc
    80821 ccagcagcat cagaaatacg tgctaatcgg caatagctat catgaagcgg aaaaagagcg
    80881 tcacgccatt gaggtgttaa ttcgccagcg ttgtaatgcg ttgattgttc actcaaaagc
    80941 attgagtgac gatgaactgg cgcaatttat ggataacatt cccggtatgg tgttaatcaa
    81001 ccgcgttgtg ccggggtacg cccatcgttg cgtttgcctg gataatctca gcggtgcccg
    81061 aatggcgacg cgcatgttgc tgaataacgg tcatcaacgt attggttatc tttcttccag
    81121 ccacggcatt gaagatgacg ccatgcgtaa agcaggctgg atgagtgcgt tgaaagagca
    81181 ggatattatt ccgccggaaa gctggattgg cactggtacg ccggacatgc cgggcggtga
    81241 ggcggcgatg gttgaactgc tggggcgcaa tctacaactt accgctgtat ttgcttataa
    81301 cgacaatatg gccgctggcg cactgacagc attaaaagat aatggcattg cgattccgtt
    81361 acatctctca atcatcggtt tcgatgatat tcccatcgcc cgttacaccg acccgcaatt
    81421 aacgaccgtg cgttatccca ttgcttcaat ggcgaaatta gccaccgaac tggccttgca
    81481 gggggcagca ggcaatattg atcctcgtgc cagccactgt tttatgccga cgttagtgcg
    81541 tcgccattct gtcgcaacac gccagaatgc ggcgacgatc actaactcaa caaatcaggc
    81601 gatgtaaccg ctttcaatct gtgagtgatt tcacagtatc ttaacaatgt gatagctatg
    81661 attgcaccgt tttaacgttg taacccgtat gtaacagtga ataatcactt tcaccgaggt
    81721 aatagcgtca taacaacaat taaagccgtt ttctggagcg ttaccgggca tggaagaacg
    81781 aattttaaaa agtgagcttc ggcgttcagt aacacttcat taactctact gccccgccga
    81841 gcatttatct caagcactac cctgcataag aaaaaccgga gataccatga ataagaaggt
    81901 gttaaccctg tctgctgtga tggccagcat gttattcggt gccgctgcac acgctgctga
    81961 tactcgcatt ggtgtaacaa tctataagta cgacgataac tttatgtctg tagtgcgcaa
    82021 ggctattgag caagatgcga aagccgcgcc agatgttcag ctgctgatga atgattctca
    82081 gaatgaccag tccaagcaga acgatcagat cgacgtattg ctggcgaaag gggtgaaggc
    82141 actggcaatc aacctggttg acccggcagc tgcgggtacg gtgattgaga aagcgcgtgg
    82201 gcaaaacgtg ccggtggttt tcttcaacaa agaaccgtct cgtaaggcgc tggatagcta
    82261 cgacaaagcc tactacgttg gcactgattc caaagagtcc ggcattattc agggcgattt
    82321 gattgctaaa cactgggcgg cgaatcaggg ttgggatctg aacaaagacg gtcagattca
    82381 attcgtattg ctgaaaggtg aaccgggcca tccggatgca gaagcacgta ccacttacgt
    82441 gattaaagag ctgaacgaca aaggcattaa aactgaacag ttacagttag ataccgctat
    82501 gtgggatacc gctcaggcga aagataagat ggacgcctgg ctgtctggcc cgaacgccaa
    82561 caaaatcgaa gtggttatcg ccaacaacga tgcgatggca atgggcgcgg tagaagcact
    82621 gaaagcacac aacaagtcca gcattccggt gtttggcgtc gatgcgctgc cagaagcgct
    82681 ggcgctggtg aaatccggtg cactggcggg cacagtactg aacgatgcta acaaccaggc
    82741 gaaagcgacc tttgatctgg cgaaaaactt ggccgatggc aaaggtgcgg ctgatggcac
    82801 caactggaaa atcgacaaca aagtggtccg cgtaccttat gttggcgtag ataaagacaa
    82861 cctggctgaa ttcagcaaga aataagactg attgggcgca gtcgtttact gcgcccttat
    82921 tgtatggcca acaaggtaaa attatatggt cagctcaacg actccgtctt ccggggaata
    82981 cttgttggaa atgagcggta tcaacaagtc ttttcctggt gttaaggcac ttgataacgt
    83041 taatttaaaa gtccggccac attctatcca tgcattaatg ggggaaaacg gcgcaggaaa
    83101 atcaacatta ttaaaatgcc tgtttggtat ttatcaaaaa gactccggca ccattttatt
    83161 ccagggtaaa gagatcgatt tccattccgc caaagaagca ctggaaaatg gtatttcgat
    83221 ggtacaccag gagttaaacc tggtattaca acgttcggtg atggataaca tgtggctggg
    83281 gcgatatccc accaaaggca tgtttgtcga tcaggacaaa atgtaccgcg aaaccaaagc
    83341 gatttttgat gaactggata ttgatatcga tccgcgtgcg cgcgtcggca cattatccgt
    83401 ttcgcaaatg cagatgatcg aaatcgccaa agcgttttcc tataacgcga aaattgtgat
    83461 tatggatgaa ccgacttctt cgttaaccga aaaagaggtc aatcatctgt tcactattat
    83521 tcgtaaatta aaagagcgcg gctgcggtat tgtttatatc tcgcataaaa tggaagaaat
    83581 cttccagtta tgtgatgaag ttaccgtatt gcgcgacggt cagtggatcg ccaccgaacc
    83641 gctggcagga ctgacgatgg acaagatcat cgccatgatg gttgggcgtt ctcttaatca
    83701 gcgttttcct gacaaagaaa acaagccggg cgaagtcatc ctcgaggtgc gtaacctaac
    83761 gtcactgcgc cagccgtcga ttcgcgatgt ctcgtttgat ctgcataaag gggagatcct
    83821 cggtattgcc gggctggtgg gggcgaaacg taccgatatt gttgagacgt tatttggtat
    83881 tcgcgagaaa tcggctggca ccattacgtt gcacggcaaa cagatcaata accataatgc
    83941 caacgaagcc ataaaccacg gatttgcact ggtaactgag gagcgccgct caacgggaat
    84001 ttatgcctat ctggatattg gttttaactc gttaatttcc aatattcgca actacaaaaa
    84061 taaagttggt ttactggata actcgcggat gaaaagcgat acccagtggg tgattgattc
    84121 gatgcgggta aaaacgccgg gtcatcggac gcaaattggt tcgctctccg gtggtaatca
    84181 gcaaaaggtg attattggtc gctggctact aacgcaacca gaaatattaa tgctcgatga
    84241 accgacgcgc ggtattgatg tcggggcgaa gtttgaaatt tatcagttaa ttgccgaact
    84301 ggcgaagaaa ggcaagggga ttattattat ctcctctgaa atgcctgagt tgttagggat
    84361 aacagaccgt attctggtca tgagcaatgg tctcgtttcc ggaattgtcg atacaaaaac
    84421 aacaacgcaa aacgaaattc tgcgtcttgc gtctttgcac ctttaagatt aggggcttcc
    84481 catgagtgcg ttaaataaga aaagttttct tacttacctg aaagagggcg gtatttacgt
    84541 cgttctttta gttttgctgg cgattattat tttccaggac ccaacatttt taagtctgtt
    84601 gaacttaagt aatattctca cccagtcatc ggtgcgtatt attatcgcgc tcggtgtggc
    84661 agggttaatt gtcacccagg ggaccgatct ttctgctggt cgtcaggtag ggctggcggc
    84721 agtggtggct gcgacattat tgcagtccat ggataacgcc aacaaagtgt tcccggaaat
    84781 ggcgacgatg ccgattgcgc tggttattct gattgtctgt gccattggtg cggtgatcgg
    84841 tttgatcaac ggtctgatta tcgcttatct caacgtgacg ccgttcatta ccacgctcgg
    84901 cacgatgatc atcgtctatg gaatcaactc gctctattac gactttgtcg gggcgtcgcc
    84961 aatttctggt tttgacagtg gcttttctac ctttgctcag ggctttgtcg cgctggggag
    85021 tttccgtctc tcttacatca ccttctacgc gttgattgcg gtggcgttcg tctgggtgtt
    85081 gtggaacaaa acccgcttcg gtaagaacat ttttgccatt ggcggtaacc cggaagcggc
    85141 aaaagtatct ggtgtcaacg tcggcctgaa cctgctgatg atctacgcgt tgtctggcgt
    85201 gttctatgcc tttggcggga tgttagaagc cggacgtatc ggctctgcca ccaacaacct
    85261 cggctttatg tatgagctgg atgctatcgc ggcgtgcgtg gtaggcggtg tatcgttcag
    85321 cggcggtgtg gggacggtga ttggcgtggt gaccggggta attattttta ccgtcatcaa
    85381 ctatggcctg acgtatatcg gcgtaaaccc atactggcag tacatcatca aaggggcgat
    85441 tattatcttc gccgtagcgc tggattcact gaaatacgcg cgtaagaagt gatgtgattg
    85501 tggatattgc cggatgcgct gcatccggca atcggtgcca aatgccggat gcgtctctgg
    85561 ttttacaacg ttaccgggtg ttctttctcg cctttcttaa acttcacttc cccgagctca
    85621 atacaaccca ccgggcagac gtgaccacaa agcagacaac ccacacattt ctcggtatta
    85681 caatgcggtg tgcgggtttt ctcgctccat tccatcgcct ggtgaccgcc gtcgtaacag
    85741 gaaatataac agcgtccaca gccaacacat ttatcaagat tgatacgggg atagacaata
    85801 taactgcggt ctaaatcttc cgccgggaca atattgttat tcgccagacc taccatctcc
    85861 tgcagcgaat caaatccctg atcggcgaga taatgcgaca acccgcttgc catatcttcc
    85921 actatccgat acccgtactg catgatgccg gtggtcacct gtaacgttgc tgcgccgagc
    85981 aataaaaact cagccgcatc ctcccaggtt tcaatgccgc cgataccgct gattgggaaa
    86041 tcgcgcagtt ctggatgggt gcgcatctgc tgaatgaagc gcagggcgat cggttttacc
    86101 gctttaccgg aatatccgga aatactcgat tttccgttaa cgatcggcat accgattttc
    86161 tgattaagat cgatattggt gatggattta acggtgttaa tcgccgcaat gccatctgcg
    86221 ccgccgcgct tcgccgccag cgccacttcg cacatatcac cgatattcgg cgtcatcttc
    86281 gccagcattg gcagcgtgga accccgtttc actgcccgac aatatttttc taccagctcc
    86341 gggctttgcc cgacatcgct acccatcgca tgagaagtca tttgcggaca ggagaagtta
    86401 cactcgatca tatccgcgcc agcttcttgc accaggcgcg ccagctcctc ccattgctgc
    86461 tcattttccc ccatgatcga agcgatcaat actttgtccg ggtaatcttc cttcagctga
    86521 cgcagggcgg ccagattctc ttccaacgga tgttcagcaa tctgctccat atttttgaag
    86581 ccgataaaac cggtatcttc tttcaccaga tgatcaaaac gcggcgagac ttcgttggcg
    86641 ataaaaaagc cgatcgtttt aaacaccacg ccgccccaac ctgtgtcgta ggctttggca
    86701 cacatctcat agcagttgcc tacaggcgaa gaagagaggc agaacgggtt gggaaacttc
    86761 acgccgcaaa aagtaatcga aagatctttc gttaacatga gcaagctccc tctaaatagt
    86821 gatgaatcgc ctcggcggct tctttcccgg ttttcacggc atagaccacg gttttgtcac
    86881 cctcaacaat atcgccagca gcaaagactt gcggatcgcg ggtctgataa ttttgtgttt
    86941 tgatggtgtt acgctgcggc tctaactccg caaaggcatc cagtctggca tgctgaccga
    87001 cggcgagaat aattttatct gccgccatcg tcagttcgcc cggtaaccgt acatgcttaa
    87061 acgtgacttt attgccttcc acggctactg gcgtgaatcc atcgatgatc gaaacgccca
    87121 gctcccgggc gctggcaaac tctttttcgc ttgccggaaa ctcatctaac tcttcacgcg
    87181 ctacgcaggt taccgcctga cagccgagaa ctttcagcgt gctggctacg tccatcgcaa
    87241 catcaccgcc gccgataatt aatgcgcttt gtggaatgct gatatcgcct tgcgcctgtc
    87301 gtgcacgttg caggaagtcg acggcaatct caacgtcgct atgctcaaac agcgataacc
    87361 cggaaccgct cgataacccc acggtgacca gtaccgcgcg gttttctgct ttcagttgct
    87421 ccagggtgag tgtgttaccg acttcgttgt tgcacttaat ggtcacgccc attttttcaa
    87481 tacgggcgat ctctgcatcc agcactgatt gcggtaaccg gaattgcgga ataccgttac
    87541 gcaaccagcc accggggtgc gcttctttct cataaatcgt gacgtcataa ccctggtttg
    87601 tcagtgttac actggcctgc aatccggcag gacctgcgcc aataatcgcg actttgccga
    87661 gcgttttagt accgggctga taaatttcca tcccggtttg ttgttcaaaa tcagtaacaa
    87721 aacgctgtaa gcgaccgata tcaatgggag tatcaacacc ggcacgggta caaccgcttt
    87781 gacataattt ctccgtcggg cacactctgg cacaaacggc accgagggca ttattttcgc
    87841 gaattgtctc ggcagcgcct ttaaaattac gaaagtagat tgagcgaata aatttccccg
    87901 gatcggtctg tgccgggcaa gcctgactac agggagcgtc atgacataat aaacagcgag
    87961 aggcttcttt aatcgccagt aaaggcgtaa aagccggagt gagttcatcc agataatttt
    88021 gttgcggcat gtgatcttcc ttaatgctat gagtaattaa ggcgaacgct aaatatactc
    88081 gtcatacttc aagttgcatg tgctgcgtct gcgttcgctc accccagtca cttacttatg
    88141 taagctcctg gggactcact cacttgtcgc cttcctgcaa ctcgaattat ttagagtata
    88201 aatattgcgt gctgatatta aggctatgcg cgtggggaaa tttatactgt gaaaggattc
    88261 acaaatagct gcggttcaga atgttatatc cgcagcttat tgagtgaagt aataattatt
    88321 ct
//
LOCUS       DAPGUL010000006        86521 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.006, whole genome shotgun sequence.
ACCESSION   DAPGUL010000006 DAPGUL010000000
VERSION     DAPGUL010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 86521)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 86521)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..86521
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.006"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..1197)
                     /gene="mdtK"
                     /locus_tag="RHX21_000453"
     CDS             complement(<1..1197)
                     /gene="mdtK"
                     /locus_tag="RHX21_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter MdtK"
                     /protein_id="HDV1985691.1"
                     /translation="MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDM
                     AAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLI
                     MLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPG
                     MVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSM
                     RDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQI
                     ALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTV
                     SLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITF
                     TAYWVLG"
     gene            1412..2053
                     /gene="ribE"
                     /locus_tag="RHX21_000454"
     CDS             1412..2053
                     /gene="ribE"
                     /locus_tag="RHX21_000454"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HDV1985692.1"
                     /translation="MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAH
                     NGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGH
                     IMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVH
                     LIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA"
     gene            complement(2093..3241)
                     /gene="cfa"
                     /locus_tag="RHX21_000455"
     CDS             complement(2093..3241)
                     /gene="cfa"
                     /locus_tag="RHX21_000455"
                     /EC_number="2.1.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclopropane fatty acyl phospholipid synthase"
                     /protein_id="HDV1985693.1"
                     /translation="MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNP
                     DFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIASAR
                     LFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMIC
                     EKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTIL
                     LQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLN
                     VDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPE
                     IADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR"
     gene            complement(3532..4743)
                     /locus_tag="RHX21_000456"
     CDS             complement(3532..4743)
                     /locus_tag="RHX21_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bcr/CflA family multidrug efflux MFS
                     transporter"
                     /protein_id="HDV1985694.1"
                     /translation="MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVS
                     ASLSLFLAGFAAAQLLWGPLSDRYGRKPVLLIGLTIFALGSLGMLWVENAATLLVLRF
                     VQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQ
                     AIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSAS
                     FFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLV
                     LFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAA
                     LQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVDCQNH
                     GNAEVAHSESH"
     gene            4856..5788
                     /locus_tag="RHX21_000457"
     CDS             4856..5788
                     /locus_tag="RHX21_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV1985695.1"
                     /translation="MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWL
                     AVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIV
                     RPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAF
                     RDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKR
                     VVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVALELENPFPDSACCLTWQQND
                     MSPALTWLLEYLGDSETLNKEWLREPEETPATGD"
     gene            complement(5785..6810)
                     /gene="purR"
                     /locus_tag="RHX21_000458"
     CDS             complement(5785..6810)
                     /gene="purR"
                     /locus_tag="RHX21_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor PurR"
                     /protein_id="HDV1985696.1"
                     /translation="MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELH
                     YSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLE
                     KQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVID
                     NAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQ
                     GDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDN
                     VRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADG
                     PFRDYRR"
     gene            7109..7198
                     /gene="ynhF"
                     /locus_tag="RHX21_000459"
     CDS             7109..7198
                     /gene="ynhF"
                     /locus_tag="RHX21_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein YnhF"
                     /protein_id="HDV1985697.1"
                     /translation="MSTDLKFSLVTTIIVLGLIVAVGLTAALH"
     gene            7364..8533
                     /locus_tag="RHX21_000460"
     CDS             7364..8533
                     /locus_tag="RHX21_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1985698.1"
                     /translation="MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGM
                     LISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPDYMTLMLSRIL
                     TSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRM
                     SFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMF
                     TLYTYISPVLQSITHATPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLL
                     MVIMLAIPFLARNEFGAAISMVVWGAATFAVVPPLQMRVMRVASEAPGLSSSVNIGAF
                     NLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS"
     gene            complement(8679..9260)
                     /gene="sodB"
                     /locus_tag="RHX21_000461"
     CDS             complement(8679..9260)
                     /gene="sodB"
                     /locus_tag="RHX21_000461"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Fe]"
                     /protein_id="HDV1985699.1"
                     /translation="MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIK
                     GTAFEGKSLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFG
                     SFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWE
                     HAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA"
     gene            complement(9388..10203)
                     /gene="mepH"
                     /locus_tag="RHX21_000462"
     CDS             complement(9388..10203)
                     /gene="mepH"
                     /locus_tag="RHX21_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-endopeptidase MepH"
                     /protein_id="HDV1985700.1"
                     /translation="MARINRISITLCALLFTTLPLTPMAHASKQARESSATTHITKKA
                     DKKKSTATTKKTQKTAKKAASKSTTKSKTASSVKKSSITASKNAKTRSKHAVNKTASA
                     SFTEKCTKRKGYKSHCVKVKNAASGTLADAHKAKVQKATKVAMNKLMQQIGKPYRWGG
                     SSPRTGFDCSGLVYYAYKDLVKIRIPRTANEMYHLRDAAPIERSELKNGDLVFFRTQG
                     RGTADHVGVYVGNGKFIQSPRTGQEIQITSLSEDYWQRHYVGARRVMTPKTLR"
     gene            10538..10885
                     /gene="grxD"
                     /locus_tag="RHX21_000463"
     CDS             10538..10885
                     /gene="grxD"
                     /locus_tag="RHX21_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monothiol glutaredoxin 4"
                     /protein_id="HDV1985701.1"
                     /translation="MSTTIEKIQRQIAENPILLYMKGSPKLPSCGFSAQAVQALAACG
                     ERFAYVDILQNPDIRAELPKYANWPTFPQLWVDGELVGGCDIVIEMYQRGELQQLIKE
                     TAAKYKSEEPDAE"
     gene            complement(10936..15552)
                     /locus_tag="RHX21_000464"
     CDS             complement(10936..15552)
                     /locus_tag="RHX21_000464"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDV1985702.1"
                     /translation="MADNPDPSSLLPDVFSPATRDWFLRAFKQPTAVQSQTWHVAARS
                     EHALVIAPTGSGKTLAAFLYALDRLFREGGEDTREAHKRKTSRILYISPIKALGTDVQ
                     RNLQLPLKGIADERRRRGETEVNLRVGIRTGDTPAQERSKLTRNPPDILITTPESLYL
                     MLTSRARETLRGVETVIIDEVHAVAGSKRGAHLALSLERLDALLHTSAQRIGLSATVR
                     SASDVAAFLGGDRPVTVVNPPAMRHPQIRIVVPVANMDDVSSVASSTGEDSHAGREGS
                     IWPYIETGILDEVLRHRSTIVFTNSRGLAEKLTARLNELYAARLQRSPSIAVDAAHFE
                     STSGATSNRVQSSDVFIARSHHGSVSKEQRAITEQALKSGELRCVVATSSLELGIDMG
                     AVDLVIQVATPLSVASGLQRIGRAGHQVGGVSKGLFFPRTRRDLVDSAVIVECMFAGR
                     LENLTPPHNPLDVLAQQTVAAAAMEALQVDEWYSRVRRAAPWKDLPRRVFDATLDMLS
                     GRYPSGDFSAFRPKLVWNRETGILTARPGAQLLAVTSGGTIPDRGMYSVLLPEGEEKA
                     GSRRVGELDEEMVYESRVNDIITLGATSWRIQQITRDQVIVTPAPGRSARLPFWRGEG
                     NGRPAELGEMIGDFLHLLADGAFFSGTIPPWLAEENTNANIQGLIDEQRNATGIVPGS
                     RHLVLERCRDEIGDWRIILHSPYGRRVHEPWALAITGRIHALWGADASVVASDDGIVA
                     RIPDTDGKLPDAAIFLFEPEKLLQIVREAVGSSALFAARFRECAARALLMPGRTPGHR
                     TPLWQQRLRASQLLEIAQGYPDFPVILETLRECLQDVYDLPALERLMRRLNGGEIQIS
                     DVTTTTPSPFATSLLFGYVAEFMYQSDAPLAERRASVLSLDSELLRNLLGQVDPGELL
                     DPQVIRQVEEELQRLAPGRRAKGEEGLFDLLRELGPMTVEDLAQRHTGSSEEVASYLE
                     NLLAVKRIFPAMISGQERLACMDDAARLRDALGVRLPESLPEIYLHRVSYPLRDLFLR
                     YLRAHALVTAEQLAHEFSLGIAIVEEQLQQLREQGLVMNLQQDIWVSDEVFRRLRLRS
                     LQAAREATRPVAATTYARLLLERQGVLPATDGSPALFASTSPGVYEGVDGVMRVIEQL
                     AGVGLPASLWESQILPARVRDYSSEMLDELLATGAVIWSGQKKLGEDDGLVALHLQEY
                     AAESFTPAEADQANRSALQQAIVAVLADGGAWFAQQISQRIRDKIGESVDLSALQEAL
                     WALVWQGVITSDIWAPLRALTRSSSNARTSTRRSHRARRGRPVYAQPVSPLVSYNTPN
                     LAGRWSLLQVEPLNDTERMLALAENMLDRYGIISRQAVIAENIPGGFPSMQTLCRSME
                     DSGRIMRGRFVEGLGGAQFAERLTIDRLRDLATQATQTRHYTPVALSANDPANVWGNL
                     LPWPAHPATLVPTRRAGALVVVSGGKLLLYLAQGGKKMLVWQEKEELLAPEVFHALTT
                     ALRREPRLRFTLTEVNDLPVRQTPMFTLLREAGFSSSPQGLDWG"
     gene            complement(15645..16292)
                     /gene="rnt"
                     /locus_tag="RHX21_000465"
     CDS             complement(15645..16292)
                     /gene="rnt"
                     /locus_tag="RHX21_000465"
                     /EC_number="3.1.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease T"
                     /protein_id="HDV1985703.1"
                     /translation="MSDNAQLTGLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITL
                     KMDEQGWLMPDTTLHFHVEPFVGANLQPEALAFNGIDPNDPDRGAVSEYEALHEIFKV
                     VRKGIKASGCNRAIMVAHNANFDHSFMMAAAERASLKRNPFHPFATFDTAALAGLALG
                     QTVLSKACQTAGMDFDSTQAHSALYDTERTAVLFCEIVNRWKRLGGWPLPAAEEV"
     gene            complement(16395..16802)
                     /gene="gloA"
                     /locus_tag="RHX21_000466"
     CDS             complement(16395..16802)
                     /gene="gloA"
                     /locus_tag="RHX21_000466"
                     /EC_number="4.4.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008500591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HDV1985704.1"
                     /translation="MRLLHTMLRVGDLQRSIDFYTKVLGMKLLRTSENPEYKYSLAFV
                     GYGPETEEAVIELTYNWGVDKYELGTAYGHIALSVDNAAEACEKIRQNGGNVTREAGP
                     VKGGTTVIAFVEDPDGYKIELIEEKDAGRGLGN"
     gene            complement(16883..17980)
                     /gene="nemA"
                     /locus_tag="RHX21_000467"
     CDS             complement(16883..17980)
                     /gene="nemA"
                     /locus_tag="RHX21_000467"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-ethylmaleimide reductase"
                     /protein_id="HDV1985705.1"
                     /translation="MSSEKLYSPLKVGAITAANRIFMAPLTRLRSIEPGDIPTPLMAE
                     YYRQRASAGLIISEATQISAQAKGYAGAPGIHSPEQIAAWKKITAGVHAENGHMAVQL
                     WHTGRISHASLQPGGQAPVAPSALSAGTRTSLRDENGQAIRVETSMPRALELEEIPGI
                     VNDFRQAIANAREAGFDLVELHSAHGYLLHQFLSPSSNHRTDQYGGSVENRARLVLEV
                     VDAGIEEWGADRIGIRISPIGTFQNTDNGPNEEADALYLIEQLGKRGIAYLHMSEPDW
                     AGGEPYTDAFREKVRARFHGPIIGAGAYTVEKAETLIGKGLIDAVAFGRDWIANPDLV
                     ARLQRKAELNPQRAESFYGGGAEGYTDYPTL"
     gene            complement(18017..18616)
                     /gene="nemR"
                     /locus_tag="RHX21_000468"
     CDS             complement(18017..18616)
                     /gene="nemR"
                     /locus_tag="RHX21_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416166.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NemR"
                     /protein_id="HDV1985706.1"
                     /translation="MNKHTEHDTREHLLATGEQLCLQRGFTGMGLSELLKTAEVPKGS
                     FYHYFRSKEAFGVAMLERHYAAYHQRLTELLQSGEGNYRDRILAYYQQTLNQFCQHGT
                     ISGCLTVKLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRENHCLTFCGEPLQQA
                     QVLYALWLGANLQAKISRSFEPLENALAHVKNIIATPAV"
     gene            18719..18958
                     /locus_tag="RHX21_000469"
     CDS             18719..18958
                     /locus_tag="RHX21_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416165.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1289 domain-containing protein"
                     /protein_id="HDV1985707.1"
                     /translation="MAEQLEFFPVQSPCRGICQSDERGFCRGCFRSRDERFNWNKMSD
                     GEKQEVLRLCRQRLMRKLRANKPASSDEPEQPSLF"
     gene            19007..19903
                     /locus_tag="RHX21_000470"
     CDS             19007..19903
                     /locus_tag="RHX21_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HDV1985708.1"
                     /translation="MVQRITIAPQGPEFSRFVMGYWRLMDWNMSARQLVSFIEEHLDL
                     GVTTVDHADIYGGYQCEAAFGEALKLAPHLRERMEIVSKCGIATTAREENVIGHYITD
                     RDHIIKSAEQSLINLATDHLDLLLIHRPDPLMDADEVADAFKHLHQSGKVRHFGVSNF
                     TPAQFALLQSRLPFTLATNQVEISPVHQPLLLDGTLDQLQQLRVRPMAWSCLGGGRLF
                     NDDYFQQLRDELAVVAEELNAGSIEQVVYAWVLRLPSQPLPIIGSGKIERVRAAVEAE
                     TLKMTRQQWFRIRKAALGYDVP"
     gene            19984..20505
                     /gene="sodC"
                     /locus_tag="RHX21_000471"
     CDS             19984..20505
                     /gene="sodC"
                     /locus_tag="RHX21_000471"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Cu-Zn] SodC2"
                     /protein_id="HDV1985709.1"
                     /translation="MKRFSLAILALVVATGAQAASEKVEMNLVTSQGVGQSIGSVTIT
                     ETDKGLEFSPDLKALPPGEHGFHIHAKGSCQPATKDGKASAAESAGGHLDPQNTGKHE
                     GPEGAGHLGDLPALVVNNDGKATDAVIAPRLKSLDEIKDKALMVHVGGDNMSDQPKPL
                     GGGGERYACGVIK"
     gene            complement(20506..22518)
                     /locus_tag="RHX21_000472"
     CDS             complement(20506..22518)
                     /locus_tag="RHX21_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDV1985710.1"
                     /translation="MNASSWSLRNLPWFKATLAQWRYALRNTIAMCLALTVAYYLNLD
                     EPYWAMTSAAVVSFPTVGGVISKSLGRIAGSLLGAIAALLLAGHTLNEPWFFLLSMSA
                     WLGFCTWACAHFTNNVAYAFQLAGYTAAIIAFPMVNITEASQLWDIAQARVCEVIVGI
                     LCGGMMMMILPSSSDATALLTALKNMHARLLEHASLLWQPETNDAIRAAHEGVIGQIL
                     TMNLLRIQAFWSHYRFRQQNARLNALLHQQLRMTSVISSLRRMLLNWPSPPGATREIL
                     EQLLTALASSQTDAYTVARIIAPLRPTNVADYRHVAFWQRLRYFCRLYLQSSQELHRL
                     QSGVDDHARLARTSALARHTDNAEAMWSGLRTFCTLMMIGAWSIASQWDAGANALTLA
                     AISCVLYSAVAAPFKSLSLLMRTLVLLSLFSFVVKFGLMVQISDLWQFLLFLFPLLAT
                     MQLLKLQMPKFAALWGQLIVFMGSFIAVTNPPVYDFADFLNDNLAKIVGVALAWLAFA
                     ILRPGSDARKSRRHIRALRRDFVDQLSRHPTLSESEFESLTYHHVSQLSNSQDALARR
                     WLLRWGVVLLNCSHVVWQLRDWESRSDPLSRVRDNCISLLRGVMSERGVQQKSLAATL
                     EELQRICDSLARHHQPAARELAAIVWRLYCSLSQLEQAPPQGTLAS"
     gene            complement(22518..23375)
                     /locus_tag="RHX21_000473"
     CDS             complement(22518..23375)
                     /locus_tag="RHX21_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310380.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HDV1985711.1"
                     /translation="MSIKTIKYFSTIIVAIVAVLAGWWLWNYYMQSPWTRDGKIRAEK
                     VSITPQVSGRIVELNIKDNQLVNAGDLLLTIDKTPFQIAELNAQAQLAKAQSDLAKAN
                     NEANRRRHLSQNFISAEELDTANLNVKAMQASVNAAQATLKQTQWQLAQTEIRAPVSG
                     WVTNLTTRIGDYADTGKPLFALVDSHSFYVIGYFEETKLRHIREGAPAQITLYSDNKT
                     LRGHVSSIGRAIYDQSVESDSSLIPDVKPNVPWVRLAQRVPVRFALDKVPGDVTLVSG
                     TTCSIAVGQ"
     gene            complement(23378..23614)
                     /locus_tag="RHX21_000474"
     CDS             complement(23378..23614)
                     /locus_tag="RHX21_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1656 domain-containing protein"
                     /protein_id="HDV1985712.1"
                     /translation="MKFMLNATGLPLQDLVFGASVYFPPFFKAFAFGFVIWLVVHRLL
                     RGWIYAGDIWHPLLMDLSLFAICVCLALAILIAW"
     gene            23815..24249
                     /gene="slyA"
                     /locus_tag="RHX21_000475"
     CDS             23815..24249
                     /gene="slyA"
                     /locus_tag="RHX21_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416159.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SlyA"
                     /protein_id="HDV1985713.1"
                     /translation="MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLP
                     PDQSQIQLAKAIGIEQPSLVRTLDQLEEKGLISRQTCASDRRAKRIKLTEKAEPLISE
                     MEAVINKTRAEILHGISAEELEQLITLIAKLEHNIIELQAKG"
     gene            complement(24296..24763)
                     /gene="slyB"
                     /locus_tag="RHX21_000476"
     CDS             complement(24296..24763)
                     /gene="slyB"
                     /locus_tag="RHX21_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein SlyB"
                     /protein_id="HDV1985714.1"
                     /translation="MIKRVLVVSMVGLSLVGCVNNDTLSGDVYTASEAKQVQNVSYGT
                     IVNVRPVQIQGGDDSNVIGAIGGAVLGGFLGNTVGGGTGRSLATAAGAVAGGVAGQGV
                     QSAMNKTQGVELEIRKDDGNTIMVVQKQGNTRFSPGQRVVLASNGSQVTVSPR"
     gene            25037..26146
                     /gene="anmK"
                     /locus_tag="RHX21_000477"
     CDS             25037..26146
                     /gene="anmK"
                     /locus_tag="RHX21_000477"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HDV1985715.1"
                     /translation="MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSL
                     KQAVLDICQGQQLTLSQFGQLDTQLGRLFADAVNALLKEQNLQARDIVAIGCHGQTVW
                     HEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHST
                     ERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGK
                     VILPLLQNMLSDPYFSQPAPKSTGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAV
                     TISEQVLLSGGCERLMVCGGGSRNPLLMARLAALLPGTEVTTTDAVGISGDDMEALAF
                     AWLAWRTLAGLPGNLPSVTGASQETVLGAIFPANP"
     gene            26244..26573
                     /gene="mliC"
                     /locus_tag="RHX21_000478"
     CDS             26244..26573
                     /gene="mliC"
                     /locus_tag="RHX21_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416156.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-type lysozyme inhibitor"
                     /protein_id="HDV1985716.1"
                     /translation="MSMKKLLLICLPVLLTGCSAFNQLVEHMQTATLEYQCDEKPLTV
                     KLNNPRQEVSFVYDNQLLHLKQGISASGARYTDGIYVFWSKGDEATVYKRDRIVLNNC
                     QLQNPQR"
     gene            26632..27288
                     /gene="pdxH"
                     /locus_tag="RHX21_000479"
     CDS             26632..27288
                     /gene="pdxH"
                     /locus_tag="RHX21_000479"
                     /EC_number="1.4.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase"
                     /protein_id="HDV1985717.1"
                     /translation="MSDNDELQQIAHLRREYTKGGLRRRDLPADPLTLFERWLSQACE
                     AKLADPTAMVVATVDEHAQPYQRIVLLKHYDEKGMVFYTNLGSRKAHQIENNPRVSLL
                     FPWHTLERQVMVIGKAERLSTLEVMKYFHSRPRDSQIGAWVSKQSSRISARGILESKF
                     LELKQKFQQGEVPLPSFWGGFRVSLEQIEFWQGGEHRLHDRFLYQRENDAWKIDRLAP
                     "
     gene            27417..28691
                     /gene="tyrS"
                     /locus_tag="RHX21_000480"
     CDS             27417..28691
                     /gene="tyrS"
                     /locus_tag="RHX21_000480"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HDV1985718.1"
                     /translation="MASSNLIKQLQERGLVAQVTDEEALAERLAQGPIALYCGFDPTA
                     DSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVD
                     KIRKQVAPFLDFDCGENSAIAANNYDWFGNMNVLTFLRDIGKHFSVNQMINKEAVKQR
                     LNREDQGISFTEFSYNLLQGYDFACLNKQYGVVLQIGGSDQWGNITSGIDLTRRLHQN
                     QVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFT
                     FMSIEEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEEGLQAAKRITECLFSGSLSA
                     LSEADFEQLAQDGVPMVEMEKGADLMQALVDSELQPSRGQARKTIASNAITINGEKQS
                     DPEYFFKEEDRLFGRFTLLRRGKKNYCLICWK"
     gene            28750..29613
                     /gene="pdxY"
                     /locus_tag="RHX21_000481"
     CDS             28750..29613
                     /gene="pdxY"
                     /locus_tag="RHX21_000481"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal kinase"
                     /protein_id="HDV1985719.1"
                     /translation="MMKNILAIQSHVVYGHAGNSAAEFPMRRLGANVWPLNTVQFSNH
                     TQYGKWTGCVMPPSHLTEIVQGIAAIDKLHTCDAVLSGYLGSAEQGEHILGIVRQVKA
                     ANPQAKYFCDPVMGHPEKGCIVAPGVAEFHVRHGLPASDIIAPNLVELEILCEHAVNN
                     VEEAVLAARELIAQGPQIVLVKHLARAGYSRDRFEMLLVTADEAWHISRPLVDFGMRQ
                     PVGVGDVTSGLLLVKLLQGATLQEALEHVTAAVYEIMVTTKAMQEYELQVVAAQDRIA
                     KPEHYFSATKL"
     gene            complement(29657..30262)
                     /gene="gstA"
                     /locus_tag="RHX21_000482"
     CDS             complement(29657..30262)
                     /gene="gstA"
                     /locus_tag="RHX21_000482"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione transferase GstA"
                     /protein_id="HDV1985720.1"
                     /translation="MKLFYKPGACSLASHITLRESGKDFTLVSVDLMKKRLENGDDYF
                     VVNPKGQVPALLLDDGTLLTEGVAIMQYLADSVPDRQLLAPVNSISRYKTIEWLNYIA
                     TELHKGFTPLFRPDTPEEYKPTVRAQLEKKLQYVNEALKDEHWICGQRFTIADAYLFT
                     VLRWAYAVKLNLEGLEHIAAFMQRMAERPEVQDALSAEGLK"
     gene            complement(30368..31870)
                     /gene="dtpA"
                     /locus_tag="RHX21_000483"
     CDS             complement(30368..31870)
                     /gene="dtpA"
                     /locus_tag="RHX21_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpA"
                     /protein_id="HDV1985721.1"
                     /translation="MSTANQKPTESVSLNAFKQPKAFYLIFSIELWERFGYYGLQGIM
                     AVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWLGDKVLGTKRVIMLGAIVLAIGY
                     ALVAWSGHDAGIVYMGMAAIAVGNGLFKANPSSLLSTCYEKNDPRLDGAFTMYYMSVN
                     IGSFFSMIATPWLAAKYGWSVAFALSVVGLLITIVNFAFCQRWVKQYGSKPDFEPINY
                     RNLLLTIIGVVALIAIATWLLHNQEVARMALGVVAFGIVVIFGKEAFAMKGAARRKMI
                     VAFILMLEAIIFFVLYSQMPTSLNFFAIRNVEHSILGLAVEPEQYQALNPFWIIIGSP
                     ILAAIYNKMGDTLPMPTKFAIGMVMCSGAFLILPLGAKFASDAGIVSVSWLVASYGLQ
                     SIGELMISGLGLAMVAQLVPQRLMGFIMGSWFLTTAGANLIGGYVAGMMAVPDNVTDP
                     LMSLEVYGRVFLQIGVATAIIAVLMLLTAPKLHRMTQDDAADKAAKAAVA"
     gene            complement(32481..33116)
                     /gene="nth"
                     /locus_tag="RHX21_000484"
     CDS             complement(32481..33116)
                     /gene="nth"
                     /locus_tag="RHX21_000484"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HDV1985722.1"
                     /translation="MNKAKRLEILTRLRENNPHPTTELNFSSPFELLIAVLLSAQATD
                     VSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIGLYNSKAENIIKTCRILLEQHNG
                     EVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCNRTQFAPGKNVEQVE
                     EKLLKVVPAEFKVDCHHWLILHGRYTCIARKPRCGSCIIEDLCEYKEKVDI"
     gene            complement(33116..33811)
                     /gene="rsxE"
                     /locus_tag="RHX21_000485"
     CDS             complement(33116..33811)
                     /gene="rsxE"
                     /locus_tag="RHX21_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxE"
                     /protein_id="HDV1985723.1"
                     /translation="MSEIKDVIVQGLWKNNSALVQLLGLCPLLAVTSTATNALGLGLA
                     TTLVLTLTNLTISTLRHWTPAEIRIPIYVMIIASVVSAVQMLINAYAFGLYQSLGIFI
                     PLIVTNCIVVGRAEAFAAKKGPALSALDGFSIGMGATCAMFVLGSLREIIGNGTLFDG
                     ADALLGSWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAGKYLIDERMKKRRAEAT
                     AERALPNGETGNV"
     gene            complement(33815..34435)
                     /gene="rsxG"
                     /locus_tag="RHX21_000486"
     CDS             complement(33815..34435)
                     /gene="rsxG"
                     /locus_tag="RHX21_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxG"
                     /protein_id="HDV1985724.1"
                     /translation="MLKTIRKHGITLALFAAGSTGLTAAINQMTKTTIAEQASLQQEA
                     LFDQVLPAERYNNALAQSCYLVTAPELGKGEHRVYIAKQDDKPVAAVLEATAPDGYSG
                     AIQLLVGADFNGTVLGTRVTEHHETPGLGDKIELRLSDWITHFAGKKISGADDAHWAV
                     KKDGGDFDQFTGATITPRAVVNAVKRAGLYAQTLPAQLSQLPACGE"
     gene            complement(34439..35497)
                     /gene="rsxD"
                     /locus_tag="RHX21_000487"
     CDS             complement(34439..35497)
                     /gene="rsxD"
                     /locus_tag="RHX21_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxD"
                     /protein_id="HDV1985725.1"
                     /translation="MVFRIASSPYTHNQRQTSRIMLLVLLAAVPGIAAQLWFFGWGTL
                     VQILLASVSALLAEALVLKLRKQSVAATLKDNSALLTGLLLAVSIPPLAPWWMVVLGT
                     VFAVIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPHEIAVNIPGFIDAIQ
                     VIFSGHTASGGDMNTLRLGIDGISQATPLDTFKTSVRAGHSVEQIMQYPIYSGILAGA
                     GWQWVNLAWLAGGLWLLWQKAIRWHIPLSFLVTLALCATLGWLFSPETLAAPQIHLLS
                     GATMLGAFFILTDPVTASTTNRGRLIFGALAGLLVWLIRSFGGYPDGVAFAVLLANIT
                     VPLIDYYTRPRVYGHRKG"
     gene            complement(35498..37624)
                     /gene="rsxC"
                     /locus_tag="RHX21_000488"
     CDS             complement(35498..37624)
                     /gene="rsxC"
                     /locus_tag="RHX21_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HDV1985726.1"
                     /translation="MLKLFSAFRKNKIWDFNGGIHPPEMKTQSNGTPLRQVPLAQRFV
                     IPLKQHIGAEGELCVSVGDKVLRGQPLTRGRGKMLPVHAPTSGTVTAIAPHSTAHPSA
                     LAELSVIIDADGEDCWIPRDGWADYRTRSREELIERIHQFGVAGLGGAGFPTGVKLQG
                     GGDKIETLIINAAECEPYITADDRLMQDCAAQVVEGIRILAHILQPREILIGIEDNKP
                     QAISMLRAVLADSNDISLRVIPTKYPSGGAKQLTYILTGKQVPHGGRSSDIGVLMQNV
                     GTAYAVKRAVIDGEPITERVVTLTGEAIARPGNVWARLGTPVRHLLNDAGFCPSADQM
                     VIMGGPLMGFTLPWLDVPVVKITNCLLAPSANELGEPQEEQSCIRCSACADACPADLL
                     PQQLYWFSKGQQHDKATTHNIADCIECGACAWVCPSNIPLVQYFRQEKAEIAAIRQEE
                     KRAAEAKARFEARQARLEREKAARLERHKSAAVQPAAKDKDAIAAALARVKEKQAQAT
                     QPIVIKAGERPDNSAIIAAREARKAQARAKQAELQQTNDAATVADPRKTAVEAAIARA
                     KARKLEQQQANAEPEEQVDPRKAAVEAAIARAKARKLEQQQSNAEPEEQVDPRKAAVE
                     AAIARAKARKLEQQQANAEPEEQVDPRKAAVEAAIARAKARKLEQQQTNAEPEEQVDP
                     RKAAVAAAIARAQAKKAAQQKVVNED"
     gene            complement(37617..38195)
                     /gene="rsxB"
                     /locus_tag="RHX21_000489"
     CDS             complement(37617..38195)
                     /gene="rsxB"
                     /locus_tag="RHX21_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxB"
                     /protein_id="HDV1985727.1"
                     /translation="MNAIWIAVAAVSLLGLAFGAILGYASRRFAVEDDPVVEKIDEIL
                     PQSQCGQCGYPGCRPYAEAISCNGEKINRCAPGGEAVMLKIAELLNVEPQPLDGEAQE
                     LTPARMVAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTH
                     CISLQPVAETPDSWKWDLNTIPVRIIPVEHHA"
     gene            complement(38195..38776)
                     /gene="rsxA"
                     /locus_tag="RHX21_000490"
     CDS             complement(38195..38776)
                     /gene="rsxA"
                     /locus_tag="RHX21_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017456621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HDV1985728.1"
                     /translation="MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLA
                     TTFVMTLASICAWLIDTWILIPLNLIYLRTLAFILVIAVVVQFTEMVVRKTSPVLYRL
                     LGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAV
                     ADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL"
     gene            complement(38853..39293)
                     /locus_tag="RHX21_000491"
     CDS             complement(38853..39293)
                     /locus_tag="RHX21_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707526.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2569 domain-containing protein"
                     /protein_id="HDV1985729.1"
                     /translation="MTTTTPQRIGGWLLGPLAWLLVALLSTTLALLLYTAALSSPQTF
                     QTLGGQALTTQILWGVSFITAIAMWYYTLWLTIAFFKRRRCVPKHYIIWLLISVLLAV
                     KAFAFSPVEDGIAVRQLLFTLLATALIVPYFKRSSRVKATFVNP"
     gene            complement(39379..39594)
                     /gene="ydgT"
                     /locus_tag="RHX21_000492"
     CDS             complement(39379..39594)
                     /gene="ydgT"
                     /locus_tag="RHX21_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription modulator YdgT"
                     /protein_id="HDV1985730.1"
                     /translation="MTVQDYLLKFRKISSLESLEKLYDHLNYTLTDDQELINMYRAAD
                     HRRAELVSGGRLFDLGQVPKSVWHYVQ"
     gene            complement(39867..39992)
                     /gene="blr"
                     /locus_tag="RHX21_000493"
     CDS             complement(39867..39992)
                     /gene="blr"
                     /locus_tag="RHX21_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division septum protein Blr"
                     /protein_id="HDV1985731.1"
                     /translation="MNRLIELTGWIVLVVSVILLGVASHIDNYQPPEQSASVQHK"
     gene            40235..41275
                     /locus_tag="RHX21_000494"
     CDS             40235..41275
                     /locus_tag="RHX21_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310359.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDV1985732.1"
                     /translation="MSDNIRVGLIGYGYASKTFHAPLIAGTPGLELAVISSSDETKVK
                     ADWPTVTVVSEPKHLFNDPNIDLIVIPTPNDTHFPLAKAALEAGKHVVVDKPFTVTLS
                     QARELDALAKSLGRVLSVFHNRRWDSDFLTLKGLLAEGVLGEVAYFESHFDRFRPQVR
                     DRWREQGGPGSGIWYDLAPHLLDQAITLFGLPVSMTVDLAQLRPGAQSTDYFHAILSY
                     PQRRVILHGTMLAAAESARYIVHGSRGSYVKYGLDPQEERLKNGERLPQEDWGYDMRD
                     GVLTRVEGEERVEETLLTVPGNYPAYYAAIRDALNGDGENPVPASQAIQVMELIELGI
                     ESAKHRATLCLA"
     gene            complement(41310..42311)
                     /gene="add"
                     /locus_tag="RHX21_000495"
     CDS             complement(41310..42311)
                     /gene="add"
                     /locus_tag="RHX21_000495"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HDV1985733.1"
                     /translation="MIDTTLPLTDIHRHLDGNIRPQTILELGRQYNISLPAQSLETLI
                     PHVQVIANEPDLVSFLTKLDWGVKVLASLDACRRVAFENIEDAARHGLHYVELRFSPG
                     YMAMAHQLPVAGVVEAVIDGVREGCRTFGVQAKLIGIMSRTFGEAACQQELEAFLAHR
                     DQITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAER
                     IGHGVKAIEDRALMDFLAEQQIGIESCLTSNIQTSTVAELAAHPLKTFLEHGIRASIN
                     TDDPGVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLSAEEKRALREKVAAK"
     gene            complement(42415..43587)
                     /gene="malY"
                     /locus_tag="RHX21_000496"
     CDS             complement(42415..43587)
                     /gene="malY"
                     /locus_tag="RHX21_000496"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional maltose regulon transcriptional
                     repressor/cystathionine beta-lyase MalY"
                     /protein_id="HDV1985734.1"
                     /translation="MFDFSKVVDRHGTWCTQWDYVADRFGTADLLPFTISDMDFATAP
                     CIIEALNQRLMHGVFGYSRWKNDEFLAAIAHWFSTQHYTAIDTQTVVYGPSVIYMVSE
                     LIRQWSETGEGVVIHTPAYDAFYKAIEGNQRTVMPVALEKQADDWFCDMGKLEAVLAK
                     PECKIMLLCSPQNPTGKVWTCDELEIMADLCERHGVRVISDEIHMDMVWGEQPHIPWS
                     NVARGDWALLTSGSKSFNIPALTGAYGIIENSSSRDAYLSALKGRDGLSSPSVLALTA
                     HIAAYQQGAPWLDALRVYLKDNLTYISDKMNAAFPELNWQIPQSTYLAWLDLRPLNID
                     DNALQKALIEQEKVAIMPGYTYGEEGRGFVRLNAGCPRSKLEKGVAGLINAIRAVR"
     gene            complement(43597..45189)
                     /gene="malX"
                     /locus_tag="RHX21_000497"
     CDS             complement(43597..45189)
                     /gene="malX"
                     /locus_tag="RHX21_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS maltose transporter subunit IICB"
                     /protein_id="HDV1985735.1"
                     /translation="MTAKTAPKVTLWEFFQQLGKTFMLPVALLSFCGIMLGIGSSLSS
                     HDVITLIPVLGNPVLQAIFTWMSKIGSFAFSFLPVMFCIAIPLGLARENKGVAAFAGF
                     VGYAVMNLAVNFWLTNKGIMPTTDAAVLKANNIQSILGIQSIDTGILGAVIAGIIVWM
                     LHERFHNIRLPDALAFFGGTRFVPIISSLVMGLIGLVIPLVWPIFAMGISGLGHMINS
                     AGDFGPMLFGTGERLLLPFGLHHILVALIRFTDAGGTQEVCGQTVSGALTIFQAQLSC
                     PTTHGFSESATRFLSQGKMPAFLGGLPGAALAMYHCARPENRHKIKGLLISGLIACVV
                     GGTTEPLEFLFLFVAPVLYVIHALLTGLGFTVMSVLGVTIGNTDGNIIDFVVFGILHG
                     LSTKWYMVPVVAAIWFVVYYVIFRFAITRFNLKTPGRDSEVASSIEKAVAGAPGKSGY
                     NVPAILEALGGADNIVSLDNCITRLRLSVKDMSLVNVQALKDNRAIGVVQLNQHNLQV
                     VIGPQVQSVKDEMAGLMHTVQA"
     gene            45364..46392
                     /gene="malI"
                     /locus_tag="RHX21_000498"
     CDS             45364..46392
                     /gene="malI"
                     /locus_tag="RHX21_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mal regulon transcriptional regulator MalI"
                     /protein_id="HDV1985736.1"
                     /translation="MATAKKITIHDVALAAGVSVSTVSLVLSGKGRISTATGERVNAA
                     IEELGFVRNRQASALRGGQSGVIGLIVRDLSAPFYAELTAGLTEALEAQGRMVFLLHG
                     GKDGEQLAQRFSLLLNQGVDGVVIAGAAGSSDDLRRMAEEKAIPVIFASRASYLDDVD
                     TVRPDNMQAAQLLTEHLIRNGHQRIAWLGGQSSSLTRAERVGGYCATLLKFGLPFHSD
                     WVLECTSSQKQAAEAITALLRHNPTISAVVCYNETIAMGAWFGLLKAGRQSGESGVDR
                     YFEQQVSLAAFTDATPTTLDDIPVTWASTPARELGTTLADRMMQKITHEETHSRNLII
                     PARLIAAK"
     gene            46504..47271
                     /gene="hdhA"
                     /locus_tag="RHX21_000499"
     CDS             46504..47271
                     /gene="hdhA"
                     /locus_tag="RHX21_000499"
                     /EC_number="1.1.1.159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-alpha-hydroxysteroid dehydrogenase"
                     /protein_id="HDV1985737.1"
                     /translation="MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN
                     ADAANHVVDEIQQLGGQAFACRCDITSEQELSALADFAVSKLGKVDILVNNAGGGGPK
                     PFDMPMADFRRAYELNVFSFFHLSQLVAPEMEKNGGGVILTITSMAAENKNINMTSYA
                     SSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRL
                     GQPQDIANAALFLCSPAASWVSGQILTVSGGGVQELN"
     gene            47500..48090
                     /gene="uidR"
                     /locus_tag="RHX21_000500"
     CDS             47500..48090
                     /gene="uidR"
                     /locus_tag="RHX21_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator UidR"
                     /protein_id="HDV1985738.1"
                     /translation="MMDNMQTEAQPTRTRILNAAREIFSENGFHSASMKAICKSCAIS
                     PGTLYHHFISKEALIQAIILQDQERALARFREPIEGIHFVDYMVESIVSLTHEAFGQR
                     ALVVEIMAEGMRNPQVAAMLKNKHMTITEFVAQRMRDAQQKGEISPDINTSMTSRLLL
                     DLTYGVLADIEAEDLAREASFAQGLRAMIGGILTAS"
     gene            48479..50290
                     /gene="uidA"
                     /locus_tag="RHX21_000501"
     CDS             48479..50290
                     /gene="uidA"
                     /locus_tag="RHX21_000501"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HDV1985739.1"
                     /translation="MLRPVETPTREIKKLDGLWAFSLDRENCGIDQRWWESALQESRA
                     IAVPGSFNDQFADADIRNYAGNVWYQREVFIPKGWAGQRIVLRFDAVTHYGKVWVNNQ
                     EVMEHQGGYTPFEADVTPYVIAGKSVRITVCVNNELNWQTIPPGMVITDENGKKKQSY
                     FHDFFNYAGIHRSVMLYTTPNTWVDDITVVTHVAQDCNHASVDWQVVANGDVSVELRD
                     ADQQVVATGQGTSGTLQVVNPHLWQPGEGYLYELCVTAKSQTECDIYPLRVGIRSVAV
                     KGEQFLINHKPFYFTGFGRHEDADLRGKGFDNVLMVHDHALMDWIGANSYRTSHYPYA
                     EEMLDWADEHGIVVIDETAAVGFNLSLGIGFEAGNKPKELYSEEAVNGETQQAHLQAI
                     KELIARDKNHPSVVMWSIANEPDTRPQGAREYFAPLAEATRKLDPTRPITCVNVMFCD
                     AHTDTISDLFDVLCLNRYYGWYVQSGDLETAEKVLEKELLAWQEKLHQPIIITEYGVD
                     TLAGLHSMYTDMWSEEYQCAWLDMYHRVFDRVSAVVGEQVWNFADFATSQGILRVGGN
                     KKGIFTRDRKPKSAAFLLQKRWTGMNFGEKPQQGGKQ"
     gene            50287..51660
                     /gene="uidB"
                     /locus_tag="RHX21_000502"
     CDS             50287..51660
                     /gene="uidB"
                     /locus_tag="RHX21_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronide transporter"
                     /protein_id="HDV1985740.1"
                     /translation="MNQQLSWRTIVGYSLGDVANNFAFAMGALFLLSYYTDVAGVGAA
                     AAGTMLLLVRVFDAFADVFAGRVVDSVNTRWGKFRPFLLFGTAPLMIFSVLVFWVPTD
                     WSHGSKVVYAYLTYMGLGLCYSLVNIPYGSLATAMTQQPQSRARLGAARGIAASLTFV
                     CLAFLIGPSIKNSSPEEMVSVYHFWTIVLAIAGMVLYFICFKSTRENVVRIVAQPSLK
                     ISLQTLKRNRPLFMLCIGALCVLISTFAVSASSLFYVRYVLNDTGLFTVLVLVQNLVG
                     TVASAPLVPGMVARIGKKNTFLIGALLGTCGYLLFFWVSVWSLPVALVALAIASIGQG
                     VTMTVMWALEADTVEYGEYLTGVRIEGLTYSLFSFTRKCGQAIGGSIPAFILGLSGYI
                     ANQVQTPEVIMGIRTSIALVPCGFMLLAFVIIWFYPLTDKKFKEIVVEIDNRKKVQQQ
                     LISDITN"
     gene            51699..52964
                     /gene="uidC"
                     /locus_tag="RHX21_000503"
     CDS             51699..52964
                     /gene="uidC"
                     /locus_tag="RHX21_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416132.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronide uptake porin UidC"
                     /protein_id="HDV1985741.1"
                     /translation="MRKIVAMAVICLTAASGLTSAYAAQLADDEAGLRIRLKNELRRA
                     DKPSAGAGRDIYAWVQGGLLDFNSGYYSNIIGVEGGAYYVYKLGARADMSTRWYLDGD
                     KSFGFALGAVKIKPSENSLLKLGRFGTDYSYGSLPYRIPLMAGSSQRTLPTVSEGALG
                     YWALTPNIDLWGMWRSRVFLWTDSTTGIRDEGVYNSQTGKYDKHRARSFLAASWHDDT
                     SRYSLGGSVQKDVSNQIQSILEKGIPLDPNYTLKGELLGFYAQLEGLSRNTSQPNDTA
                     LVSGQVTWNAPWGSVFGSGGYLRHAMNGAVVDTDIGYPFSLSLDRNREGMQSWQLGVN
                     YRLTPQFTLTFAPIVTRGYESSKRDVRIEGAGILGGMNYRVSEGPLQGMNFFLAADKG
                     REKRDGSALGDRLNYWDVKMSIQYDFMLK"
     gene            complement(53190..54698)
                     /locus_tag="RHX21_000504"
     CDS             complement(53190..54698)
                     /locus_tag="RHX21_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdgA family protein"
                     /protein_id="HDV1985742.1"
                     /translation="MNKSLVAVGVIVALGVVWTGGAWYTGKKIETHLEDMVAQANAQL
                     KLTAPESNLEVSYQNYHRGVFSSQLQLLVKPIAGKENPWIKSGQSVIFNESVDHGPFP
                     LAQLKKLNLIPSMASIQTTLVNNEVSKPLFDMAKGETPFEINSRIGYSGDSSSDISLK
                     PLNYEQKDEKVAFSGGEFQLNADRDGKAISLSGEAQSGRIDAVNEYNQKVQLTFNNLK
                     TDGSSTLASFGERVGNQKLSLEKMTISVEGKELALLEGMEISGKSDLVNDGKTINSQL
                     DYSLNSLKVQNQDLGSGKLTLKVGQIDGEAWHQFSQQYNAQTQALLAQPEIANNPALY
                     QEKVTEAFFSALPLMLKGDPVITIAPLSWKNSQGESALNLSLFLKDPATTKEAPQTLA
                     QEVDRSVKSLDAKLTIPVDMATEFMTQVAKLEGYQEDQAKKLAKQQVEGASAMGQMFR
                     LTTLQDNTITTSLQYANGQITLNGQKMSLEDFVGMFAMPALNVPAVPAIPQQ"
     gene            complement(54799..55974)
                     /gene="manA"
                     /locus_tag="RHX21_000505"
     CDS             complement(54799..55974)
                     /gene="manA"
                     /locus_tag="RHX21_000505"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416130.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase"
                     /protein_id="HDV1985743.1"
                     /translation="MQKLINSVQNYAWGSKTALTELYGMENPSSQPMAELWMGAHPKS
                     SSRVQNAAGDIVSLRDVIESNKSTLLGEAVAKRFGELPFLFKVLCAAQPLSIQVHPNK
                     RNSEIGFAKENAAGIPMDAAERNYKDPNHKPELVFALTPFLAMNAFREFSEIVSLLQP
                     VAGAHPAIAHFLQQPNAERLSELFASLLNMQGEEKSRALAILKSALDSQQGEPWQTIR
                     LISEFYPEDSGLFSPLLLNVVKLNPGEAMFLFAETPHAYLQGVALEVMANSDNVLRAG
                     LTPKYIDIPELVANVKFEAKPANQLLTQPVKQGAELDFPIPVDDFAFSLHDLSDKETT
                     ISQQSAAILFCVEGDATLWKGSQQLQLKPGESAFIAANESPVTVKGHGRLARVYNKL"
     gene            56173..57819
                     /gene="fumB"
                     /locus_tag="RHX21_000506"
     CDS             56173..57819
                     /gene="fumB"
                     /locus_tag="RHX21_000506"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000066594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fumarate hydratase"
                     /protein_id="HDV1985744.1"
                     /translation="MSNKPFHYQAPFPLKKDDTEYYLLTSEHVSVSEFEGQEILKVAP
                     EALTLLARQAFHDASFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGVL
                     PTCQDTGTAIIVGKKGQRVWTGGCDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNT
                     GTNLPAQIDLYAVDGDEYKFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRT
                     LGTAACPPYHIAFVIGGTSAETNLKTVKLASAKYYDELPTEGNEHGQAFRDVELEKEL
                     LIEAQNLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIW
                     IEKLEHNPGKYIPEELRKAGEGEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVG
                     RDIAHAKLKERMDNGEGLPQYIKDHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQ
                     LQAQGGSMIMLAKGNRSQQVTDACKKHGGFYLGSIGGPAAVLAQGSIKSLECVEYPEL
                     GMEAIWKIEVEDFPAFILVDDKGNDFFQQIQLTQCTRCVK"
     gene            57962..59365
                     /gene="fumC"
                     /locus_tag="RHX21_000507"
     CDS             57962..59365
                     /gene="fumC"
                     /locus_tag="RHX21_000507"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fumarate hydratase"
                     /protein_id="HDV1985745.1"
                     /translation="MNTVRSEKDSMGAIDVPADKLWGAQTQRSLEHFRISTEKMPTSL
                     IHALALTKRAAAKVNEDLGLLSEEKASAIRQAADEVLAGQHDDEFPLAIWQTGSGTQS
                     NMNMNEVLANRASELLGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQL
                     IPQLKTLTQTLSEKSRAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYS
                     LPHVAELALGGTAVGTGLNTHPEYARRVADELAVITCAPFVTAPNKFEALATCDALVQ
                     AHGALKGLAVSLMKIANDVRWLASGPRCGIGEISIPENEPGSSIMPGKVNPTQCEALT
                     MLCCQVMGNDVAINMGGASGNFELNVFRPMVIHNFLQSVRLLADGMESFNKHCAVGIE
                     PNRERINQLLNESLMLVTALNTHIGYDKAAEIAKKAHKEGLTLKAAALALGYLSEAEF
                     DSWVRPEQMVGSMKAGR"
     gene            complement(59362..60291)
                     /gene="tus"
                     /locus_tag="RHX21_000508"
     CDS             complement(59362..60291)
                     /gene="tus"
                     /locus_tag="RHX21_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707509.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication terminus site-binding protein"
                     /protein_id="HDV1985746.1"
                     /translation="MARYDLVDRLNTTFRQMEQELATFAAHLEQHKLLVARVFSLPEV
                     KKEDEHNPLNRIEVKQHLGNDAQSLALRHFRHLFIQQQSENRSSKAAVRLPGVLCYQV
                     DNLSQAALVSHIQHINKLKTTFEHIVTVESELPTAARFEWVHRHLPGLITLNAYRTLT
                     VLHDPATLRFGWANKHIIKNLHRDEVLAQLEKSLKSPRSVAPWTREEWQRKLEREYQD
                     IAALPQNAKLKIKRPVKVQPIARVWYKGDQKQVQHACPTPLIALINRDNGAGVPDVGE
                     LLNYDADNVQHRYKPQAQPLRLIIPRLHLYVAD"
     gene            complement(60367..61668)
                     /gene="rstB"
                     /locus_tag="RHX21_000509"
     CDS             complement(60367..61668)
                     /gene="rstB"
                     /locus_tag="RHX21_000509"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310342.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     RstB"
                     /protein_id="HDV1985747.1"
                     /translation="MKKLFIQFYLLLFVCFLVMSLLVGLVYKFTAERAGKQSLDDLMN
                     SSLYLMRSELREIPPHDWGKTLKEMDLNLSFDLRVEPLSKYHLDDISMHRLRGGEIVA
                     LDDQYTFLQRIPRSHYVLAVGPVPYLYYLHQMRLLDIALIAFIAISLAFPVFIWMRPH
                     WQDMLKLEAAAQRFGDGHLNERIHFDEGSSFERLGIAFNQMADNINALIASKKQLIDG
                     IAHELRTPLVRLRYRLEMSDNLSAAESQALNRDISQLEALIEELLTYARLDRPQNELH
                     LSEPDLPLWLSTHLADIQAVTPDKTVRIKTLAQGHYAALDMRLMERVLDNLLNNALRY
                     CHSTVETSLLLSGNRATLIVEDDGPGIAPENREHIFEPFVRLDPSRDRSTGGCGLGLA
                     IVHSIALAMGGTVNCDTSELGGARFSFSWPLWHNIPQFTSA"
     gene            complement(61672..62391)
                     /gene="rstA"
                     /locus_tag="RHX21_000510"
     CDS             complement(61672..62391)
                     /gene="rstA"
                     /locus_tag="RHX21_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416125.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RstA"
                     /protein_id="HDV1985748.1"
                     /translation="MNTIVFVEDDAEVGSLIAAYLAKHDMQVTVEPRGDQAEETILRE
                     NPDLVLLDIMLPGKDGMTICRDLRAKWSGPIVLLTSLDSDMNHILALEMGACDYILKT
                     TPPAVLLARLRLHLRQNEQATLSKGLQETSLTPYKALNFGTLTIDPINRVVTLANTEI
                     SLSTADFELLWELATHAGQIMDRDALLKNLRGVSYDGLDRSVDVAISRLRKKLLDNAA
                     EPYRIKTVRNKGYLFAPHAWE"
     gene            62520..62855
                     /locus_tag="RHX21_000511"
     CDS             62520..62855
                     /locus_tag="RHX21_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlpM family protein"
                     /protein_id="HDV1985749.1"
                     /translation="MGLVIKAALGALVVLLIGVLAKTKNYYIAGLIPLFPTFALIAHY
                     IVASERGIEALRATIIFSMWSIIPYFVYLVSLWYFTGMMRLPAAFVGSVACWGISAWV
                     LIICWIKLH"
     gene            complement(62852..63574)
                     /gene="folM"
                     /locus_tag="RHX21_000512"
     CDS             complement(62852..63574)
                     /gene="folM"
                     /locus_tag="RHX21_000512"
                     /EC_number="1.5.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydromonapterin reductase"
                     /protein_id="HDV1985750.1"
                     /translation="MGKAQPLPILITGGGRRIGLALAWHFINQKQPVIVSYRTHYPAI
                     DGLINAGAQCIQADFSTNDGVMAFADEVLKSTHGLRAILHNASAWMAEKPGAPLADVL
                     ACMMQIHVNTPYLLNHALERLLRGHGHAASDIIHFTDYVVERGSDKHIAYAASKAALD
                     NMTRSFARKLAPEVKVNSIAPSLILFNEHDDAEYRQQALNKSLMKTAPGEKEVIDLVD
                     YLLTSCFVTGRSFPLDGGRHLR"
     gene            complement(63611..64993)
                     /locus_tag="RHX21_000513"
     CDS             complement(63611..64993)
                     /locus_tag="RHX21_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDV1985751.1"
                     /translation="MEKKLGLSALTALVLSSMLGAGVFSLPQNMAAVASPAALLIGWG
                     ITGAGILLLAFAMLILTRIRPELDGGIFTYAREGFGELIGFCSAWGYWLCAVIANVSY
                     LVIVFSALSFFTDTPELRLFGDGNTWQSIVGASALLWIVHFLILRGVQTAASINLVAT
                     LAKLLPLGLFVVLAMMMFKLDTFKLDFTGLALGVPVWEQVKNTMLITLWVFIGVEGAV
                     VVSARARNKRDVGKATLLAVLSALGVYLLVTLLSLGVVARPELAEIRNPSMAGLMVEM
                     MGPWGEIIIAAGLIVSVCGAYLSWTIMAAEVPFLAATHKAFPRIFARQNAQAAPSASL
                     WLTNICVQICLVLIWLTGSDYNTLLTIASEMILVPYFLVGAFLLKIATRPLHKAVGVG
                     ACIYGLWLLYASGPMHLLLSVVLYAPGLLVFLYARKTHTHDNVLNRQEMVLIGMLLIA
                     SVPATWMLVG"
     gene            complement(65179..66123)
                     /locus_tag="RHX21_000514"
     CDS             complement(65179..66123)
                     /locus_tag="RHX21_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDV1985752.1"
                     /translation="MKLKNTLLASALLSATAFSVNAATELTPEQAAAVKPFDRVVVTG
                     RFNAIGEAVKAVSRRADKEGAASFYVVDTSDFGNSGNWRVVADLYKADAEKAEETSNR
                     VINGVVELPKDQAVLIEPFDTVTVQGFYRSQPEVNDAITKAAKAKGAYSFYIVRQIDA
                     NQGGNQRITAFIYKKDAKKRIVQSPDVIPADSEAGRAALAAGGEAAKKVEIPGVATTA
                     SPSSEVGRFFETQSSKGGRYTVTLPDGTKVEELNKATAAMMVPFDSIKFSGNYGNMTE
                     VSYQVAKRAAKKGAKYYHITRQWQERGNNLTVSADLYK"
     gene            66647..68179
                     /gene="pntA"
                     /locus_tag="RHX21_000515"
     CDS             66647..68179
                     /gene="pntA"
                     /locus_tag="RHX21_000515"
                     /EC_number="1.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit alpha"
                     /protein_id="HDV1985753.1"
                     /translation="MRIGIPRERLTNETRVAATPKTVEQLLKLGFTVAVESGAGQLAS
                     FDDKAFVQAGAEIVEGNSVWQSEIILKVNAPLDDEIALLNPGTTLVSFIWPAQNPELM
                     QKLAERNVTVMAMDSVPRISRAQSLDALSSMANIAGYRAIVEAAHEFGRFFTGQITAA
                     GKVPPAKVMVIGAGVAGLAAIGAANSLGAIVRAFDTRPEVKEQVQSMGAEFLELDFKE
                     EAGSGDGYAKVMSDAFIKAEMELFAAQAKEVDIIVTTALIPGKPAPKLITREMVDSMK
                     AGSVIVDLAAQNGGNCEYTVPGEIFTTENGVKVIGYTDLPGRLPTQSSQLYGTNLVNL
                     LKLLCKEKDGNITVDFDDVVIRGVTVIRAGEITWPAPPIQVSAQPQAAQKAAPEVKTE
                     EKCACSPWRKYALMALAIILFGWLASVAPKEFLGHFTVFALACVVGYYVVWNVSHALH
                     TPLMSVTNAISGIIVVGALLQIGQGGWVSFLSFIAVLIASINIFGGFTVTQRMLKMFR
                     KN"
     gene            68190..69578
                     /gene="pntB"
                     /locus_tag="RHX21_000516"
     CDS             68190..69578
                     /gene="pntB"
                     /locus_tag="RHX21_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000014033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit beta"
                     /protein_id="HDV1985754.1"
                     /translation="MSGGLVTAAYIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIA
                     LIATIFGPDTGNVGWILLAMVIGGAIGIRLAKKVEMTEMPELVAILHSFVGLAAVLVG
                     FNSYLHHDAGMAPILVNIHLTEVFLGIFIGAVTFTGSVVAFGKLCGKISSKPLMLPNR
                     HKMNLAALVVSFLLLIVFVRTDSVGLQVLALLIMTAIALVFGWHLVASIGGADMPVVV
                     SMLNSYSGWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFG
                     TDGSSTGDDQEVGEHREITAEETAELLKNSHSVIITPGYGMAVAQAQYPVAEITEKLR
                     ARGINVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGAND
                     TVNPAAQDDPKSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTHMLFGD
                     AKASVDAILKAL"
     gene            complement(69603..70637)
                     /gene="tqsA"
                     /locus_tag="RHX21_000517"
     CDS             complement(69603..70637)
                     /gene="tqsA"
                     /locus_tag="RHX21_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2 transporter TqsA"
                     /protein_id="HDV1985755.1"
                     /translation="MAKPIITLNGLKIVIMLGMLVIILCGIRFAAEIIVPFILALFIA
                     VILNPLVQHMVRWRVPRVLAVSILMTIIVMAMVLLLAYLGSALNELTRTLPQYRNSIM
                     TPLQALEPLLQRVGIDVSVDQLAHYIDPNAAMTLLTNLLTQLSNAMSSIFLLLLTVLF
                     MLLEVPQLPGKFQQMMARPVEGMAAIQRAIDSVSHYLVLKTAISIITGLVAWAMLAAL
                     DVRFAFVWGLLAFALNYIPNIGSVLAAIPPIAQVLVFNGFYEALLVLAGYLLINLVFG
                     NILEPRIMGRGLGLSTLVVFLSLIFWGWLLGPVGMLLSVPLTIIVKIALEQTAGGQSI
                     DVLLSDLNKE"
     gene            71049..71414
                     /gene="mdtJ"
                     /locus_tag="RHX21_000518"
     CDS             71049..71414
                     /gene="mdtJ"
                     /locus_tag="RHX21_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug/spermidine efflux SMR transporter
                     subunit MdtJ"
                     /protein_id="HDV1985756.1"
                     /translation="MYIYWILLGLAIATEITGTLSMKWASVSEGNGGFILMLVMISLS
                     YIFLSFAVKKIALGVAYALWEGIGILFITLFSVLLFDESLSLMKIAGLTTLVAGIVLI
                     KSGTRKARKPELEVNHGAV"
     gene            71401..71730
                     /gene="mdtI"
                     /locus_tag="RHX21_000519"
     CDS             71401..71730
                     /gene="mdtI"
                     /locus_tag="RHX21_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug/spermidine efflux SMR transporter
                     subunit MdtI"
                     /protein_id="HDV1985757.1"
                     /translation="MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAA
                     VLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWILFGQRLNRKGWIGLVLLLAG
                     MIMVKLA"
     gene            complement(71769..72590)
                     /locus_tag="RHX21_000520"
     CDS             complement(71769..72590)
                     /locus_tag="RHX21_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HDV1985758.1"
                     /translation="MRTTIAVVLGAISLTSAFVFADKPDVAKSANDEVSTLFFGHDDR
                     VPVNDTTQSPWDAVGQLETASGNLCTATLIAPNLALTAGHCLLTPPKGKADKAVALRF
                     VSNKGLWRYEIHDIEGRVDPTLGKRLKADGDGWIVPPAAAPWDFGLIVLRNPPSGITP
                     LPLFEGDKAALTAALKSAGRKVTQAGYPEDHLDTLYSHQNCEVTGWAQTSVMSHQCDT
                     LPGDSGSPLMLHTDDGWQLIGVQSSAPAAKDRWRADNRAISVTGFRDKLDQLSQK"
     gene            complement(72690..72773)
                     /locus_tag="RHX21_000521"
     CDS             complement(72690..72773)
                     /locus_tag="RHX21_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1985759.1"
                     /translation="MVGRYRFEFILIILILCALIAARFYLS"
     gene            complement(72866..73201)
                     /locus_tag="RHX21_000522"
     CDS             complement(72866..73201)
                     /locus_tag="RHX21_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310330.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid shock protein"
                     /protein_id="HDV1985760.1"
                     /translation="MKKQIEGMTMKKVLALVVAAAMGLSSAAFAAETATTPAPTATTT
                     KAAPAKTTHHKKQHKAAPAQKAQAAKKHHKNTKAEQKAPEQKAQAAKKHAGKHSHQQP
                     AKPAAQPAA"
     gene            complement(73598..74851)
                     /locus_tag="RHX21_000523"
     CDS             complement(73598..74851)
                     /locus_tag="RHX21_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1985761.1"
                     /translation="MSRTTTVDGAPASDTDKQSISQPNQFIKRGTPQFMRVTLALFSA
                     GLATFALLYCVQPILPVLSQEFGLTPANSSISLSISTAMLAIGLLFTGPLSDAIGRKP
                     VMVTALLLASICTLLSTMMTSWHGILIMRALIGLSLSGVAAVGMTYLSEEIHPSFVAF
                     SMGLYISGNSIGGMSGRLISGVFTDFFNWRIALAAIGCFALASALMFWKILPESRHFR
                     PTSLRPKTLFINFRLHWRDRGLPLLFAEGFLLMGSFVTLFNYIGYRLMLSPWHVSQAV
                     VGLLSLAYLTGTWSSPKAGTMTTRYGRGPVMLFSTGVMLFGLLMTLFSSLWLIFAGML
                     LFSAGFFAAHSVASSWIGPRAKRAKGQASSLYLFSYYLGSSIAGTLGGVFWHNYGWNG
                     VGAFIALMLVIALLVGTRLHRRLHA"
     gene            74958..75851
                     /locus_tag="RHX21_000524"
     CDS             74958..75851
                     /locus_tag="RHX21_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV1985762.1"
                     /translation="MNIELRHLRYFVAVAEELHFGRAAARLNISQPPLSQQIQALEQQ
                     IGARLLARTNRSVLLTAAGKQFLADSRQILSMVDDAAARAERLHQGEAGELRIGFTSS
                     APFIRAVSDTLSLFRRDYPDVHLQTREMNTREQIAPLIEGTLDMGLLRNTALPETLEH
                     AVIVHEPLMAMIPHDHPLANNPNVTLAELAKEPFVFFDPHVGTGLYDDILGLMRRYHL
                     TPVITQEVGEAMTIIGLVSAGLGVSILPASFKRVQLNEMRWVPIAEEDAVSEMWLVWP
                     KHHEQSPAARNFRIHLLNALR"
     gene            75986..77206
                     /gene="mlc"
                     /locus_tag="RHX21_000525"
                     /gene_synonym="dgsA"
     CDS             75986..77206
                     /gene="mlc"
                     /locus_tag="RHX21_000525"
                     /gene_synonym="dgsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor Mlc"
                     /protein_id="HDV1985763.1"
                     /translation="MVAENQPGHIDQIKQTNAGAVYRLIDQLGPVSRIDLSRLAQLAP
                     ASITKIVREMLEAHLVQELEIKEAGNRGRPAVGLVVETEAWHYLSLRISRGEIFLALR
                     DLSSKLVVEESQELALKDDSPLLDRIISHIDQFFIRHQKKLERLTSIAITLPGIIDTE
                     NGIVHRMPFYEDVKEMPLGEALEQHTGVPVYIQHDISAWTMAEALFGASRGARDVIQV
                     VIDHNVGAGVITDGHLLHAGSSSLVEIGHTQVDPYGKRCYCGNHGCLETIASVDSILE
                     LAQLRLNQSMSSMLHGQPLTVDSLCQAALRGDLLAKDIITGVGAHVGRILAIMVNLFN
                     PQKILIGSPLSKAADILFPVISDSIRQQALPAYSQHISVESTQFSNQGTMAGAALVKD
                     AMYNGSLLIRLLQG"
     gene            77331..78026
                     /gene="bioD"
                     /locus_tag="RHX21_000526"
     CDS             77331..78026
                     /gene="bioD"
                     /locus_tag="RHX21_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310326.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent dethiobiotin synthetase BioD"
                     /protein_id="HDV1985764.1"
                     /translation="MLKRFFITGTDTSVGKTVVSRALLQALASQGKTVAGYKPVAKGS
                     KETPEGLRNKDALVLQSVSTIELPYEAVNPIALSEEESSVAHSCPINYTLISNGLANL
                     TDKVDHVVVEGTGGWRSLMNDLRPLSEWVVQEQLPVLMVVGIQEGCINHALLTAQAIA
                     NDGLPLIGWVANRINPGLAHYAEIIDVLGKKLPAPLIGELPYLPRAEQRELGQYIRLA
                     MLRSVLAVDRVTV"
     gene            complement(77979..79271)
                     /gene="clcB"
                     /locus_tag="RHX21_000527"
     CDS             complement(77979..79271)
                     /gene="clcB"
                     /locus_tag="RHX21_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated ClC-type chloride channel ClcB"
                     /protein_id="HDV1985765.1"
                     /translation="MHHLHIYPDLRTMFRRLLIATVVGILAAFAVAGFRHAMLLLEWL
                     FLNNDSGSLVNAATNLSPWRRLLTPALGGLAAGLLLMGWQKFTQQRPHAPTDYMEALQ
                     TDGQFDYAASLVKSLASLLVVTSGSAIGREGAMILLAALAASCFAQRFTPRQEWKLWI
                     ACGAAAGMAAAYRAPLAGSLFIAEVLFGTMMLASLGPVIISAVVALLVSNLINHSDAL
                     LYNVQLSVTVQARDYALIISTGVLAGLCGPLLLTLMNACHRGFVSLKLAPPWQLALGG
                     LIVGLLSLFTPAVWGNGYSTVQSFLTAPPLLMIIAGIFLCKLCAVLASSGSGAPGGVF
                     TPTLFIGLAIGMLYGRSLGLWFPDGEEITLLLGLTGMATLLAATTHAPIMSTLMICEM
                     TGEYQLLPGLLIACVIASVISRTLHRDSIYRQHTAQHS"
     gene            complement(79430..80044)
                     /gene="dmsD"
                     /locus_tag="RHX21_000528"
     CDS             complement(79430..80044)
                     /gene="dmsD"
                     /locus_tag="RHX21_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707489.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tat proofreading chaperone DmsD"
                     /protein_id="HDV1985766.1"
                     /translation="MTHFSQQDNFSVAARVLGALFYYAPESAEAAPLVAVLTSDGWET
                     QWPLPEASLAPLVTAFQTQCEETHAQAWQRLFVGPWALPSPPWGSVWLDRESVLFGDS
                     TLALRQWMREKGIQFEMKQNEPEDHFGSLLLMAAWLAENGRQTECEELLAWHLFPWST
                     RFLDVFIEKAEHPFYRALGELARLTLAQWQSQLLIPVAVKPLFR"
     gene            complement(80087..80941)
                     /locus_tag="RHX21_000529"
     CDS             complement(80087..80941)
                     /locus_tag="RHX21_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit"
                     /protein_id="HDV1985767.1"
                     /translation="MGNGWHEWPLVIFTVLGQCVVGALIVSGIGWFAAKNDADRQRIV
                     RGMFFLWLLMGIGFIASVMHLGSPLRAFNSLNRIGASGLSNEIAAGSIFFAVGGLWWL
                     VAVIGKMPQALGKLWLLVSMALGVIFVWMMTCVYQIDTVPTWHNGYTTLAFFLTVLLS
                     GPILAAAILRAARVTFNTTPFAIISVLALIACAGVIVLQGLSLASIHSSVQQASALVP
                     DYASLQVWRVVLLCAGLGCWLCPLIRRREPHVAGLILGLILILGGEMIGRVLFYGLHM
                     TVGMAIAG"
     gene            complement(80943..81560)
                     /gene="dmsB"
                     /locus_tag="RHX21_000530"
     CDS             complement(80943..81560)
                     /gene="dmsB"
                     /locus_tag="RHX21_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit B"
                     /protein_id="HDV1985768.1"
                     /translation="MTTQYGFFIDSSRCTGCKTCELACKDFKDLGPEVSFRRIYEYAG
                     GDWQEDNGVWHQNVFAYYLSISCNHCDDPACTKVCPSGAMHKREDGFVVVDEDVCIGC
                     RYCHMACPYGAPQYNAEKGHMTKCDGCYSRVAEGKQPICVESCPLRALEFGPIEELRQ
                     KHGTLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPEEV"
     gene            complement(81571..83994)
                     /locus_tag="RHX21_000531"
     CDS             complement(81571..83994)
                     /locus_tag="RHX21_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416105.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase subunit A"
                     /protein_id="HDV1985769.1"
                     /translation="MKIHTTEALMKAEISRRSLMKTSALGSLALASSAFTLPFSQMVR
                     AAEAPVEEKAVWSSCTVNCGSRCLLRLHVKDDTVYWVESDTTGDDVYGNHQVRACLRG
                     RSIRRRMNHPDRLKYPMKRVGKRGEGKFERISWDEALDTISDNLRRILKDYGNEAVHV
                     LYGTGVDGGNITNSNVPYRLMNSCGGFLSRYGSYSTAQISAAMSYMFGANDGNSPDDI
                     ANTKLVVMFGNNPAETRMSGGGVTYYVEQARERSNARMIVIDPRYNDTAAGREDEWLP
                     IRPGTDGALACAIAWVLITENMVDQPFLDKYCVGYDEKTLPANAPRNAHYKAYILGEG
                     PDGIAKTPEWAAKITSIPAEKIIQLAREIGSAKPAYICQGWGPQRHSNGEQTSRAIAM
                     LSVLTGNVGINGGNSGVREGSWDLGVEWFPMLENPVKTQISVFTWTDAIDHGTEMTAT
                     RDGVRGKEKLDVPIKFLWCYASNTLINQHGDINHTHEVLQDDSKCEMIVGIDHFMTAS
                     AKYCDILLPDLMPTEQEDLISHESAGNMGYVILAQPATSAKFERKPIYWMLSEVAKRL
                     GPDVYQTFTEGRSQHEWIKYLHAKTKERNPEMPDYEEMKTTGIFKKKCPEEHYVAFRA
                     FREDPQANPLKTPSGKIEIYSERLAKIADTWELKKDEIIHPLPAYTPGFDGWDDPLRK
                     TYPLQLTGFHYKARTHSSYGNIDVLQQACPQEVWINPIDAQARGIRHGDTVRVFNNNG
                     EMLIAAKVTPRILPGVTAIGQGAWLKADMFGDRVDHGGSINILTSHRPSPLAKGNPSH
                     SNLVQIEKV"
     gene            complement(84055..86481)
                     /locus_tag="RHX21_000532"
     CDS             complement(84055..86481)
                     /locus_tag="RHX21_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase subunit A"
                     /protein_id="HDV1985770.1"
                     /translation="MSKNDRMVGISRRTLVKSTAIGSLALAAGGFSLPFTLRSAAAAV
                     QQASEKVIWGACSVNCGSRCALRLHVKDNEVTWVETDNTGSDEYGNHQVRACLRGRSI
                     RRRINHPDRLNYPMKRVGTRGEGKFERISWDEALDTIASSLKKTVEQYGNKAVYIQYS
                     SGIVGGNMTRSSPSASAVKRLMNCYGGSLNQYGSYSTAQISCAMPYTYGSNDGNSTTD
                     IENSKLVVMFGNNPAETRMSGGGITYLLEKAREKSNAKMIVIDPRYTDTAAGREDEWL
                     PIRPGTDAALVAGIAWVLINENLVDQPFLDKYCVGYDEKTLPADAPKNGHYKAYILGE
                     GDDNTAKTPQWASQITGIPVDRIIKLAREIGTAKPAYICQGWGPQRQANGELTARAIA
                     MLPILTGNVGISGGNSGARESTYTITIERLPVLDNPVKTSISCFSWTDAIDHGPQMTA
                     IRDGVRGKDKLDVPIKFIWNYAGNTLVNQHSDINKTHEILQDESKCEMIVVIENFMTS
                     SAKYADILLPDLMTVEQEDIIPNDYAGNMGYLIFLQPVTSEKFERKPIYWILSEVAKR
                     LGPDVYQKFTEGRTQEQWLQHLYAKMLAKDPALPSYDELKKMGIYKRKDPNGHFVAYK
                     AFRDDPEANPLKTPSGKIEIYSSKLAEIARTWELEKDEVISPLPVYASTFEGWDSPER
                     RTFPLQLFGFHYKSRTHSTYGNIDLLKAACRQEVWINPIDAQKRGIANGDMVRVFNHR
                     GEVRLPAKVTPRILPGVSAMGQGAWHEANMSGDKIDHGGCVNTLTTLRPSPLAKGNPQ
                     HTNLVEIEKI"
BASE COUNT        21683 a        21633 c        22404 g        20801 t
ORIGIN      
        1 gcccagcacc cagtaagccg taaaggtgat atagaaaatg gaacgcgtat ctttataacc
       61 acgcaaaatc ccactgccaa tcacctggat tgagtcagaa atctgatata ccgccgccag
      121 caacatcaaa tgcgcagcca gcgttacaac ctcgggattg tcgttgtaca acagggcgat
      181 ttgctcccgc agtgaaaccg tgaatatggc cgtcagggtt gccatacaga cacccaccat
      241 aagcccggtc cgcgcagcgg tttgcgcatc cagcgttgag ccctgaccca gacgataacc
      301 tacgcggata gttaccgctg ccgccagcga cattggaagc acaaacatca gtgaactaaa
      361 gttcagggca atctggtgtc ctgcgacatc aacaataccg agcggagaca ctaacagagc
      421 cacgacggca aacagtgtca cttcaaagaa tagtgccagc gcaatcggca aaccgagttg
      481 aatcagtcgt ttcatcaccg caggatcggg tttcgcggtg cctttttcgt tacgaatatc
      541 gcgcatggag cgggcgcgtt taatgtaaga aaccatggca aggaacatga cccaatacac
      601 cgccgcagta gccacgccac aaccaacgcc accgagctca ggcataccga aatgaccata
      661 aataaagata tagttcaccg gaatgttcac cagcaggccg ataaagccca ttaccatacc
      721 cggcttggtt tttgccagac cttcacattg gttacgggca acctggaaga acagatagcc
      781 cggcgcgccc cacaacaacg cacgcagata acccacggct ttgtccgcca gagccggatc
      841 gatgttttcc atggagcgga taatgtaacc tgcattccac agcacaagca taatgagaac
      901 ggaaacaaaa cctgccagcc agaaaccttg tcgcacctga tgcgcaatgc gctcacgtcg
      961 accggaacca tttaattgcg cgataaccgg cgttaatgcc agcagcagtc cgtgaccaaa
     1021 gaggatcgcc ggaagccaga tagaagtacc gatagcgacc gccgccatgt cggtggcact
     1081 atagccgccc gccatcacgg tatcgacaaa acccatcgca gtttgggcga tttgcgcgag
     1141 aatcaccggg attgctaatg ctaataacag acgcgcttca ctgatatact tctgcacgtg
     1201 aacacctttt atttgtagtt atatgagaga ctaaaaagcc gcctgaatgg gcagcaaaaa
     1261 gaagaagcag gggaaattca gtctattgta gcgaggattt attaattctc cagtgaaaaa
     1321 atagtcattc ttaccccttc actggtaagg gcgtttgcca cctgctattg tgctgaacag
     1381 aatgtcttaa ctgatttcag gagttgtaag tatgtttacg gggattgtac agggcaccgc
     1441 aaaactggtg tcgattgacg agaaaccaaa ttttcgtacg catgtggtgg agttacccga
     1501 ccacatgctg gacggcctgg aaacaggtgc ttccgtggcg cataacggtt gctgcctgac
     1561 cgtgacggaa attaacggca accatgtcag ttttgacctg atgaaagaaa cgttacgcat
     1621 taccaatctt ggcgatttaa aagtggggga ttgggtaaac gttgagcgtg cggcgaaatt
     1681 cagtgatgaa attggcggac acttaatgtc aggtcatatt atgaccaccg ctgaagtggc
     1741 gaaaatatta acctcggaaa ataatcgcca gatctggttt aaagtccagg atagtcagtt
     1801 gatgaaatat atcctgtaca aaggatttat tggcatcgac ggtattagcc tgaccgtcgg
     1861 cgaagtcacg ccaacgcgtt tttgcgtcca tttaattccg gaaactctgg aacgcacgac
     1921 tcttgggaag aaaaaactcg gcgcacgcgt caacattgaa attgatccac aaactcaggc
     1981 agtggtagat acggtagaac gtgtgctggc ggcacgagaa aatgccatga atcaaccagg
     2041 tacagaagcc tgatctgaaa tcgcccccgg agagggggcg atagaatagc ctttagcgag
     2101 cgactcgaag gccgttttca acaccgcgtg agaacacgac ctgccagagc tgaatatcac
     2161 gggcgcggaa agcacctgca caggcattca gataataggt aaacattcgt ttaaagcgtt
     2221 cactgtagtt atccgcaatt tctggccatg cggcgaggaa tcgttcatac cacgccatca
     2281 acgtagtatc gtaatcagca ccgaagttat gccagtcttc catcacgaag tggggttcgc
     2341 tggattgagc aatctggcgt acagagggca ggcaaccgtt cggaaaaata tatttattaa
     2401 tccagggatc aacattcaga tcggtttttt tcgaaccgat agtatggagc aggaatatac
     2461 cttccggttt caaattacga tccaccaccg caaaataggt atcgtaattt ttcggtccga
     2521 cgtgctcgaa catccccaca gaaacaatac gatcaaactg gtcgttcagg tcacgataat
     2581 cttgcagcaa aatggtgaca tccaggcctt cacagcgttc ctgagccatt ttttgctgtt
     2641 cggcagaaat ggtgacgccg accacgctta cgtcatagtt agatgccatg tagtgcgcca
     2701 gtccgcccca gccgcagcca atatccagta cgcgcatccc tggttttaac tgcaattttt
     2761 cacaaatcat tttgagcttc gcctgctggg cagattccag attatcggca tctttccagt
     2821 aagcgcagga atattgcatg aagggatcaa gcatgcggct gaacaagtca ttacccaaat
     2881 cgtaatgctc cttgccgact atccaggcac gttttttact ctgcagattg aagagacgag
     2941 cgctggcaat acgcagcgtg tctttgaaat gatgggggag ttggttctcg agacctgcgc
     3001 gtaagacttt gctaaaaaac atatccagtc ggtcacattc ccaccagcca tccatataac
     3061 tttcgcctaa ccccaaagag ccttcttgca gaacgcgttt aaaaaaatcg gggtttttca
     3121 cacgaatatc cgccggggca gaaccgttaa tggctatacc ggcacggcta agtaattcgt
     3181 tggcgatacg gtaccagttg tcatccggta cactgacttc ttctatacac gatgaactca
     3241 tagtttctcc atcactggtc ggtgatcaga accttaaaac agcgtagacg ctttttgggc
     3301 tttgtgagaa atctcgcaga aaaaaccgcg agtctataat ccgacgtaga acagagggaa
     3361 aggaggaacc cttgccgaaa tgaccatcca tagtgagtcg ggaacgatcc tgtccccgta
     3421 aaaacataat atttatcgta gctttaacaa ctcgaaatta gtataggccg ctaatttcaa
     3481 tcatacaaca aaattttgtt agcagcctaa gtataagtat atcgatatag atcagtgtga
     3541 ttcgctatga gcgacttcgg cattgccatg attctggcag tcaacttctt cacaacgttg
     3601 catcatgtaa cccagagcga ccagcactac tgttgataac atcacgctgg tggtggtgag
     3661 caatggcgtg ctgatactga tcagccagga aactaccaga cttgcgagga agcacagacc
     3721 cagttgtaga gtgttctgca acgctgcggc gcgaccagtt gcgtgtggga agggacgcag
     3781 cgcctgggcg acaacaatcg ggtagatcgc gccattggca atcgccatca cacagaatgg
     3841 gatcaggatt tcgaccagcg acacatggct aatgaagcct gcagcccagg tcgcaatgac
     3901 gctgactgca aacagcacca gcaaccacgg taataactgc ttgccttgcc atttctgcag
     3961 cgcggcgcga cagccataac caccaatcag aaacgcgata gtttgcggga cataacttaa
     4021 accaataact gccgggctgt agcccatttc actaaggatg aacggtgaac cggtcagcca
     4081 tgcaaaaaaa ctggctgaac aggccgcgta tatcagcacg ttgccgcgat aggttttaga
     4141 acgtagcagg tcggtaaagg tcagaccatc ctgactattg ttacgggcct tcgtcgtggg
     4201 tttgagccag aaaataggca gaatcagcac cacggtaatg gcaaacaggg tggcgaaaat
     4261 cgcctgccag gaaaaatgga ccagcagcca gcttcctaac agaggagcca gggccggaga
     4321 tagacccacc agcggcatga tggtcgcaaa aattcggtta actttctgtg aaggataata
     4381 atccgtcact aacgcttgcc agataaccgc cgcggcgcag acacccacag cctgtacaaa
     4441 acgcaatacc agcagcgtag cggcgttttc tacccacagc atccccagac tacctaacgc
     4501 aaaaattgtc aggccgatta ataacaccgg tttacgacca taacggtcgg agagtggccc
     4561 ccacagaagc tgggctgcgg caaaaccggc aaggaacaga ctaaggctgg cactgacagc
     4621 agacgcaggc gtttgcaggt cggcctgtat ggcggcgaaa gcaggcagat acatatcggt
     4681 tgccagaaaa ccgagtacgc tcaaacccgc cagccagact aaaaatcttt tcccaggttg
     4741 catgtatatt ctctaaatct ctcaattaaa caccgccgca aagtgtaggg agtgaaatta
     4801 gtgttgtgaa acggtaatat ttgatgactg gtttcaaaaa ttttgcaggc agactatgtg
     4861 gtcagaatat tcactcgaag ttgttgatgc ggtagcgcgt aatggtagtt ttagcgctgc
     4921 ggcacaggag ctgcatcgcg ttccttctgc ggtcagctat accgtgcgtc agctggaaga
     4981 gtggctggcg gtgccgctct ttgaacgacg gcaccgtgat gtggagctga ccgctgctgg
     5041 agcgtggttt ctcaaagaag ggcgctctgt tgtcaaaaaa atgcagatca cccgccagca
     5101 atgtcagcag atagcgaacg gctggcgcgg tcagttagct atcgcagtgg ataatattgt
     5161 caggccagaa cgtacacggc agatgatcgt tgatttttat cgccattttg atgatgtcga
     5221 acttcttgtc tttcaggaag tgttcaacgg tgtctgggat gcgctttccg acgggcgcgt
     5281 ggaactggcg attggcgcaa cacgcgcgat tccggtaggc ggtcgttatg ccttccggga
     5341 tatggggatg ctaagctgga gttgcgttgt tgccagccac cacccgctgg cgttgatgga
     5401 tggcccattc agcgatgata cgttgcgcaa ctggccgtcg ttggtgcgcg aagacacctc
     5461 gcgaacgcta cctaaacgta ttacctggtt gctggataac caaaaaagag ttgtcgtgcc
     5521 tgactgggaa tcatcggcaa cctgtatctc ggcaggatta tgcataggga tggtgccaac
     5581 acatttcgcc aaaccgtggc ttaatgaggg gaagtgggta gcacttgaat tggaaaaccc
     5641 cttcccggat tcggcatgtt gtctgacatg gcagcaaaat gatatgtcgc ctgcgttaac
     5701 ctggctgctt gagtatctcg gcgatagtga gacgctgaat aaggagtggc tgcgggagcc
     5761 ggaagagact cccgcaacgg gtgattaacg acgatagtcg cggaacgggc cgtcagccac
     5821 ggagcggcgt tcaatcaagc gcggatgcac ttcaatggac tgcggttctt cacgtttgtt
     5881 gacgatacga tccaacagca tgttgaacgc tgtttcaccc agcgaatctt ttggctggtg
     5941 gatcgtggtc agcgccggcg taaaatagcg ggcgttgcgc acgttatcat aaccgatcag
     6001 cgaaacatcc tgcgggacgc gcagacccat ttcatcagca gcacaaagtg cgcccattgc
     6061 catgatatcg ccaccacaga agacggcagt agggcgatgc ggctgcgaca gtatttgctg
     6121 catggcgcga taaccagatt cgggttcaaa gtcaccctga acaatccagc tttccggcac
     6181 cttgatcatc gcttcttcca tcgccttcat aaaaccggca aggcggcctg cgccggtgtt
     6241 acgttccagc gggccaggga tgacgccgat ttcgcggtga ccgcgttcaa tcagataacg
     6301 cccggccatg tagccgcctt cgaacgcgtt atcaatgacc gcatcggtga agtcagcttt
     6361 tgcttcaccc cagtccatca ccaccattgg gatatggcga tactcttcca gcatcgccag
     6421 caacggctct gggtactcag aacacatcac cagcagacca tcgacgcgtt tttgcgccat
     6481 catcgacaga taagcccgct gtttctcaag attgttccac gcattaccca gaatcagggt
     6541 gtaacctttc tggaagcaat ttttttcaac cgcttcaatg atctcggcaa aataggccgc
     6601 ttcgctgctg gtcgccagca aaccgataga cttggtgtgg ttaaccttca ggctacgcgc
     6661 caccgcgcta ggggagtagt gtaattcttt aatcgctgcc cacacggcgt tgcgcgtttc
     6721 ttcagcgacg aaacgtgttt tgttgattac gtgtgacaca gttgtagtgg aaacgtttgc
     6781 tcgtttcgct acatctttta ttgttgccat tccatttcac tccagaccct aacttcagct
     6841 cctgcaaaat cgcaaggtaa acgtttgcct ttacacacct tacgcacaac aaaagtgttg
     6901 cggtacgccg gaaaaacgac acggagcgtc aggaaggggt caatggccag tacgcaaata
     6961 gtgtaagcgt ggaattttgg ccgatcttga cgaaaagggg aagtggtaaa aacacttatc
     7021 attataaatg acgggagatt ttttcatcac agtgtgtaaa aatgcgtaat atcacttttt
     7081 gtgtggtaat aaaaaaggag aaaacttgat gagcaccgac cttaaatttt cactggtaac
     7141 aacgattatc gtcctcggtt tgatcgtagc cgtgggtttg actgccgcgc tgcactgatt
     7201 tcctctcgag ggagcgcgtt ctccctcgca tctccttcct gtttgttagc aaaatggcaa
     7261 aagtgttttc tctttttgtt attttcattt ttttgtgatt gctgtcatgc tttcgccact
     7321 ttaatgaata tcgcgtaatg acgcgaagag gtggagataa ggcatgaaaa ttaactatcc
     7381 gttgctggcg ctggcgattg gcgcgtttgg tatcgggaca acggagttct cgccaatggg
     7441 tttgttgccc gtcattgcgc gcggtgtgga tgtctcgatt cccgctgccg gaatgttaat
     7501 cagtgcctat gcagttggcg taatggttgg cgcgccgctg atgacgcttc tactttctca
     7561 tcgtgcccgc cgcagtgcgt tgattttcct gatggcaatt ttcacgctcg gcaacgtact
     7621 ttccgccatc gcgccggatt atatgaccct gatgctttca cgcattttga ccagcctgaa
     7681 tcacggagca ttttttggtt tgggttcagt cgtggccgca agcgtggtgc caaaacataa
     7741 acaggccagc gcagttgcca ctatgtttat ggggttaacc ctggcaaata tcggtggcgt
     7801 gccggcggcg acctggttgg gtgaaaccat cggctggcgg atgtcatttc tggcaacggc
     7861 ggggctggga gtgatttcaa tggtaagtct gttcttctca ttacctaaag gtggtgcagg
     7921 ggcacgacct gaagtgaaaa aagagctggc ggtattaatg cgtccgcagg tgctgtctgc
     7981 attgctgacg acggtactgg gagctggtgc aatgtttact ctctacacct atatctctcc
     8041 ggtactacaa agtattaccc acgcaacacc agtgttcgtc acggcaatgc tggtgctgat
     8101 tggtgtcgga ttctctatcg gtaactatct cggcggcaaa ctggcagatc gttcagttaa
     8161 cggcacgttg aaaggctttt tgttgttgtt gatggtgatt atgctggcaa tcccgttcct
     8221 ggcccgcaat gagttcggcg cagctattag catggtggtg tggggcgcag caacctttgc
     8281 ggtcgtaccg ccgttacaga tgcgcgtgat gcgtgtcgcc agtgaagcgc cgggtctgtc
     8341 ttcatcagtc aatattggtg cctttaatct tggaaatgcg ctgggagcag ctgctggtgg
     8401 tgcggtaatt tccgctgggc tgggatacag ctttgtgccg gtgatgggag cgattgtcgc
     8461 gggactggca ttattgctgg tgtttatgtc agccagaaaa caacctgaaa cagtttgcgt
     8521 tgctaacagc taattaaaca aaaacgcaga aggataacct tctgcgttac agttgctgac
     8581 aacgtgcgat ttatcttgcc gaatgcgctg ttaacgcctc atccgcgttg gcatggtaag
     8641 cgaagcgcat caggcaatgc tgcatttgcc atcagttatt atgcagcgag atttttcgct
     8701 acgaattccc agttcaccag cgcccagaag tgctccagat agccaggacg tgcattgcga
     8761 tagtcgatgt aataagcgtg ttcccagaca tcaacggtca gcagcggagt cgcatcggtg
     8821 gtcagcggag tacccgcgtt agaggttgaa acgatagcca gtttgccatc gctgtttttc
     8881 accagccagg tccagccaga accaaagttt ttgatcgctg catcagtaaa ctgcgctttg
     8941 aaatcggcaa agctgccaaa agatgcggcg atagcttcag cgacttttcc agtcggttcg
     9001 ccaccggcgt tcggtgccag gcagttccag tagaaagtat ggttccagac ctgagctgcg
     9061 ttgttgaata cgccaccttc agagctgcga ataatctctt ccagtgattt accttcaaac
     9121 gcggtacctt taatcaggtt gttcaggtta gtgacataag tctgatgatg cttgccgtag
     9181 tgatactcga tagtttccgc agaaatgtgc ggtgccagag catctttagc atatggtagt
     9241 gcaggtaatt cgaatgacat tgctactctc ctttattatt aatttgcata cgtacaatag
     9301 ccttattgtg cgtatggata gggtagcaaa ttaaaaggtg agacaaaaga tgaacttacc
     9361 ctgttgccgt aacaacaggg taaagtttta gcgaagtgtt tttggggtca ttacccgacg
     9421 agcgccaaca tagtggcgct gccagtagtc ttcactgaga gaagtgattt gaatttcctg
     9481 acctgtgcgc ggtgactgaa taaatttgcc gttgccgaca tacacgccga catgatcggc
     9541 tgtgccgcgt ccctgagtac ggaaaaagac caggtcgccg tttttcagtt cactacgttc
     9601 gattggcgct gcatcacgca ggtgatacat ttcattcgcc gtacgcggaa tacgaatttt
     9661 caccaaatct ttataagcgt aataaaccag gccgctgcaa tcaaaaccgg tacgcggtga
     9721 gctgccaccc caacgatatg gcttaccaat ttgctgcatc agtttattca ttgccacttt
     9781 cgtagctttt tgcaccttcg ctttgtgcgc gtcggcaaga gttcctgacg cggcattttt
     9841 gactttcaca caatgcgatt tatagccctt acgtttggta cacttttcgg taaagctggc
     9901 tgaggccgtt ttattgacgg cgtgtttgct gcgagttttg gcgtttttag aagcggtaat
     9961 ggaagatttt ttaacggaag aagcggtttt gcttttggtc gtacttttac tggcggcttt
    10021 tttcgctgtt ttctgggtct ttttggtggt tgccgtgctt ttctttttat ctgctttttt
    10081 ggtgatatga gtggtagcag aactctccct ggcttgcttt gaagcatggg ccataggcgt
    10141 taaaggcagg gtggtaaaaa gtaaagcaca gagcgtgatc gaaatacggt ttatccgcgc
    10201 cactgagcgt ccctctgtta aggcaggtct atcatgcctg cgtctgattt acaaaacttg
    10261 atgattctaa tgcatagaag aagagaaagt taatagcttt tattgttaaa aaatacgttt
    10321 cgttggcgag cgcaaaaaaa tgcagcagtg aaagctaaaa atggttataa atacgccagt
    10381 ttgccgcgca tcagagaaga aacgaatatt tgaaatgcaa caaatagagc aaagggataa
    10441 aatagcaaaa gcgtgatgaa aatgttattt tccgatgccg cactgacccg ctacaatgtc
    10501 agattactgc cgtaaagaag tttgaggaag caagacaatg agcaccacta tcgaaaaaat
    10561 ccaacgccag attgctgaaa acccgatcct gctgtacatg aaaggttcac cgaaactgcc
    10621 gagctgcggt ttctctgccc aggcagtcca ggcgcttgcc gcatgtggcg aacgttttgc
    10681 ctatgttgat attctgcaga atccggacat tcgtgcggaa ctgccgaaat atgctaactg
    10741 gccgaccttc ccgcaactgt gggttgacgg cgagctggtc ggcggttgtg atatcgtgat
    10801 cgaaatgtat cagcgtggcg aactgcagca gctgatcaaa gaaactgccg ctaaatacaa
    10861 gtctgaagag ccggacgcgg aataatccgt cctgcaatac tgacggatgc gaacgggcat
    10921 ccgtcagtcc tttctctatc cccaatccag cccttgtggc gaacttgaaa atcccgcctc
    10981 acgcagcagc gtaaacatcg gcgtttgccg gaccggtaga tcattcactt ctgttagcgt
    11041 aaagcgcagc cgtggttcgc gacgcagtgc ggtagtcagc gcgtggaaaa cctctggggc
    11101 gagtaattcc tctttttcct gccagaccag catttttttg ccaccttgcg ccagatagag
    11161 taacaatttg ccgccagaaa cgaccaccag cgcacccgcc cgacgcgttg gaaccagcgt
    11221 tgccggatgt gcaggccagg gcagaagatt tccccacaca ttagccggat cgttggcaga
    11281 gagcgccact ggtgtatagt ggcgcgtttg cgtggcttgt gtcgccagat cgcgcaatcg
    11341 gtcaatagtc agacgttcag cgaattgcgc gccacccaga ccttctacaa aacgacctcg
    11401 cataattcgc ccggagtctt ccatacttcg acaaagcgtt tgcatcgatg gaaacccgcc
    11461 agggatattt tcggctatca ccgcctgacg actgatgatg ccgtagcggt cgagcatatt
    11521 ttccgccagc gccagcatcc tttcggtatc gtttagtggc tccacctgca ataacgacca
    11581 gcgtccagcc agatttggtg tgttgtaaga taccagcggc gagacgggtt gcgcatagac
    11641 aggacgtcca cgacgagccc ggtgactgcg gcgagttgag gtgcgtgcgt tggaactgct
    11701 gcgggtgagg gcgcgtaacg gtgcccaaat gtcgctggtg atgacgcctt gccagaccag
    11761 cgcccataac gcctcttgca gggcagagag atcaaccgat tcgccgattt tgtcgcgtat
    11821 ccgttggctg atttgttgtg caaaccaggc tcctccgtca gccagaacag cgactatcgc
    11881 ttgttgcagc gccgaacgat tcgcctgatc cgcttcggcg ggagtgaacg attctgcagc
    11941 atattcctgt agatgcagtg ccaccaggcc gtcatcttca cccagttttt tttgccccga
    12001 ccagataact gcaccggttg ccagtaattc atcgagcatt tctgacgaat agtcgcgtac
    12061 gcgggcaggc aggatctggc tttcccagag tgaggcgggt aaaccgactc cggcaagctg
    12121 ttcgatcacc cgcatcacgc catctacgcc ctcataaacg cctggcgatg ttgaggcaaa
    12181 gagcgccggg ctaccatcgg tggcgggtaa tacgccctga cgttccagca gcaatcgcgc
    12241 ataggtcgtg gctgcaacgg gacgcgtcgc ttctctggcg gcttgcagcg agcgcaaacg
    12301 cagacgacga aatacttcat cgctcaccca gatgtcttgt tgcagattca tcaccagacc
    12361 ctgttcacgc agttgctgaa gctgctcttc gacaatggca ataccgagac taaactcatg
    12421 agccagttgt tcagccgtga ccagagcatg agcccggaga tagcgcagaa agaggtcgcg
    12481 aagcgggtaa ctgactctat gtaaataaat ctctggcaat gactctggta gtcgtacgcc
    12541 gagggcatca cgcagcctgg cggcatcatc catacaggca agacgctcct gtccgctaat
    12601 catcgctggg aagattcgtt ttactgcaag aagattttcc agatacgacg caacctcttc
    12661 actgctgcct gtatgccgtt gcgccaggtc ttcaacggtc attggcccca gttcgcgcag
    12721 caggtcgaac aatccttctt cacctttcgc tcttctgcca ggagccagtc gttgcaactc
    12781 ttcttccacc tggcgaatga cctgcgggtc gagtaattcc cccggatcga cctgtccgag
    12841 tagattgcgc agtaactcgc tgtccagcga cagtacggat gcccggcgct ctgccagcgg
    12901 ggcgtcgctc tggtacataa attccgcgac atagccgaac aataaacttg tggcgaaagg
    12961 cgagggcgta gtggtcgtta catcggatat ttgaatttcg ccaccgttca ggcgacgcat
    13021 caaacgttcc agtgcgggaa gatcataaac atcttgcaga cattcgcgca gggtttcgag
    13081 aatgaccgga aaatccggat atccctgagc gatttccagc aactgactgg cgcgcagccg
    13141 ttgttgccaa agcggggtgc gatggcccgg agtgcgcccc ggcattaata atgcccgcgc
    13201 ggcgcattcg cgaaaacggg cggcgaaaag tgccgagctg cctaccgcct cgcggacaat
    13261 ttgcagcaac ttttctggtt caaacaaaaa aatcgcggcg tcgggcaatt taccatcagt
    13321 gtcaggaatg cgcgcaacaa tgccgtcatc actggcgacc acagacgcgt cagcgcccca
    13381 tagggcatgt attcgcccgg taatcgccag cgcccagggt tcatgcaccc gtcttccata
    13441 gggagagtgc aaaataatac gccagtcgcc aatttcatca cggcaccgtt cgaggaccag
    13501 atggcgactc cccggaacga tgcccgtcgc gttgcgttgc tcgtcaatca acccctgaat
    13561 attggcgttc gtattttctt ctgccagcca cgggggaata gtcccggaaa agaacgcgcc
    13621 atccgccagc aaatgaagaa aatcgccgat catctcgcct aattcagccg gacgtccgtt
    13681 accttcacca cgccagaagg ggagccgggc agaacgaccc ggagcaggag tcacaatcac
    13741 ctgatcgcgg gtgatttgct ggatccgcca tgaggtagcg ccgagagtga taatgtcgtt
    13801 cacccgcgac tcatatacca tctcctcatc cagttcaccc acccgccgcg aaccggcctt
    13861 ttcttcacct tcgggtaata acacgctata catgccacga tccggaatgg tgccgccgct
    13921 ggtaaccgcc aacaattgag cgccaggtcg ggcggtcaat atcccggtct ccctgttcca
    13981 gaccagtttg gggcgaaaag cagaaaaatc gccagaggga tagcgcccgg aaagcatatc
    14041 cagcgtggcg tcaaaaacac gtcttggcag atctttccac ggtgcggcac ggcgtacgcg
    14101 ggagtaccat tcgtctacct gtaatgcctc catcgccgcg gcggcaacgg tttgctgcgc
    14161 aaggacgtcg agtggattat gcggcggtgt caggttttcc agcctgcctg cgaacataca
    14221 ctctacaatg actgcggaat cgactaagtc acgccgggta cgagggaaaa acagcccttt
    14281 agatacaccg ccaacctgat gtccggcgcg accaatgcgt tgtaacccac tggcaacaga
    14341 aagcggcgtt gccacctgaa tcaccagatc cactgcgccc atatcaatcc ccagttcgag
    14401 actggaggtt gcgaccacgc agcgtaactc acccgatttc agcgcctgct cggtgattgc
    14461 tcgttgttct ttagagacgg agccgtggtg tgagcgggca ataaaaacgt cgctactttg
    14521 tacacggtta gaggttgcgc cggaggtcga ctcgaaatgg gccgcatcaa cggcgataga
    14581 cggggaacgc tgtaagcgtg cggcgtaaag ctcatttaat cgtgccgtca gtttttccgc
    14641 cagcccacgt gaattagtaa agacaatggt cgagcgatgg cgcaacactt catcaaggat
    14701 acccgtttca atatatggcc agatggagcc ttcccggccg gcatggctgt cttcgccggt
    14761 gctgctggcg accgatgaga catcatccat attggcgacc ggtacgacaa ttcgtatctg
    14821 cggatggcgc attgcgggcg ggttgactac cgtaaccggg cgatcgccac caagaaatgc
    14881 tgccacatcg ctggctgagc gcacagtggc agaaaggcca attcgctgtg ctgaggtgtg
    14941 gagcagcgca tcgagccgct ccagacttaa cgccagatgc gcaccacgtt tactgcccgc
    15001 taccgcgtgg acttcatcaa taattaccgt ttcgacgccg cgtagcgttt cgcgcgcgcg
    15061 ggaggtcagc atcagataga gtgattcggg tgtggtgatc agaatatccg gcggattacg
    15121 ggtgagtttg ctgcgttcct gtgcaggcgt atcgccagta cggatcccta cgcgaagatt
    15181 gacttccgtt tcgccgcgcc gccgccgttc atcggcaata cccttcaacg ggagctgcaa
    15241 gttgcgctga acgtcggtgc ccagagcttt tatcggtgaa atatagagga tgcgtgaggt
    15301 tttacgctta tgcgcctcgc gggtatcttc gccgccttcg cggaagagcc gatcgagggc
    15361 gtagagaaat gctgccagcg ttttcccgga gccggtcggt gcaatcacca gcgcatgttc
    15421 gcttcgcgcc gccacatgcc aggtttgcga ctggacagcg gtcggctgtt taaaggcgcg
    15481 aagaaaccag tcgcgggtcg ccggtgaaaa cacgtccggc aggagcgatg aagggtctgg
    15541 attatctgcc attaacgcta ttccccgtga atatcatgca ggatgcgtgg aatagcctca
    15601 ctatagatgc ctgaatcatt gcatgtcatc aggcatcgac tcgattacac ctcttcggcg
    15661 gcaggtagcg gccagcctcc cagacgtttc cagcggttga cgatttcaca aaacagcaca
    15721 gcagtgcgtt cggtgtcgta cagcgcggag tgcgcctggg tgctgtcgaa gtccatgcca
    15781 gcggtctggc aagcctttga caatacggtt tgtccgagtg ccagcccggc cagtgcagca
    15841 gtgtcaaaag tggcgaaagg gtggaacggg ttacgtttca gtgaggcgcg ttctgcggcg
    15901 gccatcataa agctgtgatc aaaattggca ttgtgcgcca ccataatggc gcggttacag
    15961 ccgctcgctt taataccttt acgtacaact ttaaaaattt cgtgcagcgc ctcgtattcg
    16021 ctgaccgcgc cgcgatcggg atcgttcggg tcaatgccgt tgaaggcgag ggcctctggc
    16081 tgcaaatttg cgccgacaaa tggttcgacg tggaaatgta atgtggtgtc cggcatcagc
    16141 cagccttgtt catccatttt cagggtgatg gcggcaatct caagcagcgc atcggttttg
    16201 gcgttaaatc cggctgtttc aacatcgatc acaacaggat aaaaaccacg aaaacggtcg
    16261 cacagaccgg taagttgagc gttatcggac atctgattct cttaatacgg ataaattgca
    16321 gcgcgcatta tgacaaatat tacttgtcga tgcagtaaag atgcgggcgc gatgagttca
    16381 cgcccggcag gagattagtt gcccagaccg cgaccggcgt ctttctcttc gattaactca
    16441 attttgtaac cgtccggatc ttccacaaac gcgataaccg tagtaccgcc ttttaccgga
    16501 cccgcttcac gggtcacgtt acccccgttt tgacggattt tttcgcacgc ttcagcggcg
    16561 ttatctacgc taagcgcgat gtgaccataa gcagtgccga gttcgtattt atccacgccc
    16621 cagttgtagg tcagttcaat caccgcttct tcggtttccg ggccgtagcc aacaaacgcc
    16681 agtgagtatt tgtattccgg gttttcgctg gtacgcagca gtttcatgcc cagcactttg
    16741 gtataaaaat cgatggagcg ttgcagatcg ccaacgcgca gcatggtatg aagaagacgc
    16801 atctttttat cctcaaaatg gctaacagat tcaaaatgtt gttttagtat agcggcggct
    16861 ttacgccgct cgcaatgttg gattacaacg tcgggtaatc ggtatagcct tccgcgccgc
    16921 caccgtagaa actttcggca cgctgtgggt taagctcagc tttgcgctgc aagcgggcga
    16981 ccagatccgg gttcgcaatc cagtcacgac caaatgccac cgcatcaatt aaccctttgc
    17041 cgatcagcgt ttcagctttt tctactgtgt atgcacctgc gccgataatc ggaccgtgga
    17101 aacgggcgcg tactttttcg cggaacgcat cagtatacgg ttcacccccc gcccaatctg
    17161 gttctgacat atgcagataa gcaatgccgc gtttacccag ttgttcaatc agatacagtg
    17221 catcggcttc ttcattcggg ccgttatccg tgttctggaa agtaccgatt ggcgaaatgc
    17281 gaatgccaat gcgatcggca ccccattctt caatcccggc atcgaccact tccagtacca
    17341 gacgtgcgcg attttccacg ctgccgccgt actgatcggt acgatggttt gaagaaggag
    17401 aaaggaactg atgcagcaaa taaccgtgag cagagtggag ctctaccaga tcaaaaccgg
    17461 cttcacgcgc gttagcaatg gcctgacgga aatcattgac gatacctgga atctcttcca
    17521 gttcaagcgc acgcggcatg gatgtttcaa cacggatcgc ctgaccattt tcatcgcgca
    17581 gagaagtacg tgttcccgcg ctaagtgctg aaggcgctac cggtgcctga ccgccaggtt
    17641 gcaggctggc gtgagaaatg cgtccggtgt gccacagctg cacggccata tgaccatttt
    17701 cagcatgaac gccagcggtg atttttttcc atgcggcaat ttgctccgga ctatggatgc
    17761 caggcgcacc tgcatatcct tttgcctggg cagaaatttg cgtggcttca ctaataatca
    17821 aaccggcact ggcacgttgg cgatagtatt ccgccatcaa cggggtagga atgtcacccg
    17881 gttcaatact gcgcagacgc gtcagcggtg ccataaaaat acggtttgcc gccgtgatcg
    17941 cgcccacttt cagtggggaa tacagttttt cagatgacat aaaggctccc ggtcgtctgg
    18001 tgataaaaaa tgcctgctaa acggcaggcg tcgcaataat gttttttaca tgggccagcg
    18061 cgttttccag tggctcgaaa ctgcgcgaaa ttttggcctg cagattcgca cccagccata
    18121 gtgcgtaaag cacttgtgcc tgttgtagcg gttcgccaca aaaggttaaa caatggttct
    18181 cacggccatt ttccagcgcc tgagagagca gggcgatcac gccgcgagca cctttatcca
    18241 tcgcgctgcg catatcttct gacagatcgc acacttcggc agagagtttt actgtcaggc
    18301 aaccactgat ggttccatgt tggcaaaact ggttcagtgt ttgctggtaa taagccagta
    18361 tgcggtcgcg gtagttacct tcgccggatt gcagcaactc agtcagtcgc tggtgatatg
    18421 cggcgtaatg acgctcaagc atggcaacgc caaacgcttc tttagagcga aagtagtgat
    18481 agaaggaccc tttcggcact tcagcggttt ttagtaattc gcttagcccc atcccggtga
    18541 atccacgttg caggcaaagt tgctcgcccg tcgccaggag atgttcgcga gtatcatgtt
    18601 cggtgtgttt gttcatgcgt tggagtgtag tagaccagtc ggtctagtgc aagcaaagtt
    18661 gctactttgg acattaacag cttcaataat ggtaataatc ttatctgagg agggcgaagt
    18721 ggcggagcaa ttagagttct ttcccgtcca gagcccgtgc cggggaattt gccagtctga
    18781 cgaacgcggg ttttgtcgcg gctgttttcg tagtcgggat gagcgtttta actggaataa
    18841 aatgagcgat ggcgaaaaac aagaggtgct gcgcctttgt cggcagcgat taatgcgcaa
    18901 attacgcgca aataagccag cgtcatcaga cgaaccggag caaccatcac tcttttgaac
    18961 ctaatcttgc gtatactcct ctcatatctg ataagaggaa gcgattatgg ttcagcgtat
    19021 tactattgcg ccgcaaggcc cggagttttc ccgttttgtg atgggctact ggcgattgat
    19081 ggactggaat atgtccgccc gccagctggt cagttttatt gaagagcatc tggatctcgg
    19141 cgtgaccacc gtggaccatg ctgatattta tggtggctat cagtgcgaag cggcgtttgg
    19201 cgaggcactg aaactggcac ctcacctgcg tgaacggatg gaaatcgtca gtaaatgcgg
    19261 tatcgcgacg accgcgcgtg aagaaaacgt cattggtcat tacatcactg accgcgatca
    19321 catcattaag agcgccgaac agtcgctaat taatctcgcg accgatcatc tggatctgct
    19381 gttaatccac cgaccagacc cgttaatgga tgccgatgaa gtggcggacg cgttcaaaca
    19441 tctgcatcag agcggcaaag tgcgtcattt tggcgtatcg aactttacgc ctgcgcaatt
    19501 tgccctgttg caatcacgtc tgccgtttac ccttgccact aatcaggtgg aaatatcccc
    19561 ggtgcatcag ccgttactgc tggatggcac gctcgaccaa ctacaacaac tgcgtgttcg
    19621 tccgatggcg tggtcctgcc ttggtggtgg tcgtctgttt aatgatgatt atttccagca
    19681 gctgcgtgat gaactggctg tggtggcaga ggagttaaac gcgggctcga ttgaacaggt
    19741 ggtttacgcc tgggtattac gtttaccatc gcagccgctg ccaattatcg gttcaggtaa
    19801 aattgagcgc gtacgggcag ctgtcgaagc agaaacactg aaaatgaccc gtcaacaatg
    19861 gtttcgtatc cgtaaagcgg cactggggta cgacgtaccg taagcacttt taggaatagc
    19921 cgccgttcaa aaatgtgtca ctggtttaca cttattcagg aatgcacaat gaacggaggt
    19981 cctatgaaac gttttagtct ggctattctg gcgctggttg ttgcaaccgg cgcacaagct
    20041 gccagtgaaa aagtcgagat gaacctcgtc acgtcgcaag gggtagggca gtcaattggt
    20101 agcgtcacca ttactgaaac cgataaaggt ctggagtttt cgcccgatct gaaagcatta
    20161 ccccccggtg aacatggctt ccatattcat gccaaaggaa gctgccagcc agccaccaaa
    20221 gatggcaaag ccagcgccgc ggaatccgca ggcgggcatc ttgatccaca aaataccggt
    20281 aaacatgaag ggccagaagg tgccgggcat ttaggcgatc tgcctgcact ggtcgtcaat
    20341 aatgacggca aagctaccga tgccgtcatc gcgcctcgtc tgaaatcact ggatgaaatc
    20401 aaagacaaag cgctgatggt ccacgttggc ggcgataata tgtccgatca acctaaaccg
    20461 ctgggcggtg gcggtgaacg ctatgcctgt ggtgtaatta agtaattacg aggccagcgt
    20521 accttgcggt ggtgcttgct caagttgcga aagcgagcag tacagccgcc agacaattgc
    20581 cgccagctca cgggcggcag gttgatgatg acgggcaagg ctgtcgcaaa tccgctgtaa
    20641 ttcttcaagt gtggccgcca gtgatttttg ctgaacgcca cgctcactca tcactccccg
    20701 caacagtgaa atacagttat cccgtactcg cgataacgga tcggaacgcg attcccagtc
    20761 gcgcaattgc cagacaacat gagaacagtt cagcagcact acaccccagc gtaataacca
    20821 acggcgagcc agcgcatcct ggctgttact caactgactg acgtgatgat aagtgagcga
    20881 ttcaaattcg ctttcactca gtgttggatg gcggcttagc tgatcgacaa aatcccggcg
    20941 cagcgcgcga atatggcggc ggcttttacg agcatccgat cctggacgca gaatggcgaa
    21001 cgctagccaa gccagcgcaa cgccaacgat ttttgccaga ttatcgttaa gaaaatcagc
    21061 aaaatcatac accgggggat tagtgacagc gataaacgaa cccataaaaa caatcagttg
    21121 cccccacagt gcggcaaatt tgggcatctg caatttaaga agctgcattg tcgccagcag
    21181 tggaaagaga aacagtaaaa attgccacag atcgctaatc tggaccatca ggccaaattt
    21241 gaccacaaag ctgaatagcg aaagtaacac cagcgtgcgc atcagcagtg acaacgactt
    21301 aaacggtgct gcgacggcgg agtagagtac gcagctaatt gctgccagcg ttaatgcatt
    21361 ggcaccggca tcccattgcg atgcaatact ccatgcgcca atcatcatca acgtacaaaa
    21421 tgtacgcagc ccgctccaca tagcttcggc gttgtcggta tgacgagcca gagcggatgt
    21481 ccgtgcgagt ctggcatgat catctacacc gctttgcaga cgatgtaatt cctgactact
    21541 ttgcagataa aggcggcaaa aataacgtag tcgctgccag aaggcgacgt gccggtagtc
    21601 ggcgacgttg gtcgggcgta gcggggcgat aatacgtgcg acggtgtaag catctgtttg
    21661 cgaactggcg agcgccgtca gcaattgttc gagaatttct cgcgtggcac ctggcggtga
    21721 gggccagttg agcaacatac gtcgcaggct ggagatgaca ctggtcatac gtaattgctg
    21781 gtggagtagc gcattaaggc gcgcgttttg ctggcgaaaa cgatagtggc tccagaaagc
    21841 ctggatacgc agcaaattca tggtcagtat ctgcccaatc accccctcat gtgctgcacg
    21901 aatggcatcg tttgtttcag gctgccagag taaactggca tgttccagta atcgggcgtg
    21961 catgtttttc aatgcggtta aaagggctgt agcatcggaa ctgctaggca ggatcatcat
    22021 catcattccg ccgcacaaaa taccgactat cacctcgcaa acgcgcgcct gagcgatatc
    22081 ccacagctgg ctggcctcag taatattaac catcggaaag gcgatgatgg cagccgtgta
    22141 gcccgccagt tgaaatgcat acgcgacgtt attcgtgaag tgcgcacagg cccaggtaca
    22201 aaagccaagc cacgccgaca tgctcaatag aaaaaaccac ggctcattga gcgtatgccc
    22261 ggcaagaagc agtgccgcaa tggctcccag taaactgcca gcgatgcgtc cgaggctttt
    22321 gctgatgaca ccgccaacgg tgggaaagct aaccactgca gccgaggtca tcgcccaata
    22381 gggttcatcc agattcaaat aataggcaac cgtcagcgcc agacacatgg caatggtatt
    22441 gcgtaacgca taacgccatt gcgccagcgt ggccttgaac cagggcaaat tgcgcaagga
    22501 ccatgacgat gcgttcatta ttgacctacg gcaatgctac aggtggtgcc cgacaccagc
    22561 gtgacatcgc ctggaacttt atccagcgca aagcggacgg gaacgcgttg ggcgagacga
    22621 acccagggga cgttaggttt cacatccgga ataaggcttg agtcactttc aacgctttga
    22681 tcataaatcg cccgaccgat actggaaacg tgaccccgta acgttttgtt atcactatag
    22741 agggtaattt gtgctggtgc accttcgcgg atatggcgca acttggtttc ttcaaaataa
    22801 ccaatgacgt aaaacgagtg gctgtcgaca agggcaaaca gcggtttccc ggtgtcagcg
    22861 taatcgccga tgcgggtagt gaggttagtc acccaaccac tcaccggggc gcgaatttcc
    22921 gtttgcgcca gttgccattg tgtctgtttc agcgtggcct gtgcggcatt aacactggcc
    22981 tgcatcgctt taacattgag gttagcggta tcgagttctt cggcagaaat aaaattttgt
    23041 gagagatgac gacgacgatt cgcttcgtta ttggcttttg cgaggtcaga ttgcgctttc
    23101 gccagctgag cctgtgcgtt cagctcggcg atctgaaagg gcgttttatc gatcgtgagc
    23161 agaagatccc ccgcgttaac cagttggttg tcttttatat tcagctcaac aatacgtccc
    23221 gacacctgtg gggtgataga aaccttttct gcgcgtattt tcccgtcgcg tgtccacgga
    23281 gattgcatgt aataattcca cagccaccat ccggcaagaa ccgcaactat cgctacaatg
    23341 attgttgaga aatacttaat tgttttaatt gacatagtta ccacgcaatc agtattgcca
    23401 gagcaaggca aacgcaaatc gcaaacagcg ataaatccat taacaaggga tgccagatgt
    23461 caccggcgta gatccagcca cgaagcaggc ggtgtacgac aagccagatg acgaatccaa
    23521 acgcgaaggc tttgaaaaac ggaggaaaat agacggacgc accgaacacc agatcttgta
    23581 agggcaatcc tgttgcattg agcataaact tcacaaagta gattccttta cgaccgaata
    23641 tattgcgtta gattaataaa tattctttaa gtgcgaaaaa tttacgcgca atttctgaaa
    23701 aatatgtctg acggtaacca aatgcagcaa tacatttgtt ttagcaatac aattgctgca
    23761 cactattcta aaagccgcat aatatcttag caagctaatt ataaggagat gaaattggaa
    23821 tcgccactag gttctgatct ggcacggttg gtgcgcatat ggcgtgctct gatagaccat
    23881 cgcctgaaac cgctggagtt aacacaaacc cattgggtta cgttacacaa tatccatcag
    23941 ttacctccag accagtcgca aattcaactg gcaaaagcga ttggcatcga gcagccatca
    24001 ctggtccgta ctctggacca actggaagaa aaagggttaa tttcgcgtca aacttgtgcc
    24061 agcgatcgtc gggctaaacg tattaaactg acggaaaagg cagagccact gatcagcgaa
    24121 atggaagctg ttattaacaa aacccgcgcg gaaatattac atggcatctc cgcagaggaa
    24181 ctggagcaac tgattacgct catcgcaaaa cttgagcata atatcattga gttacaggcc
    24241 aaagggtgaa atgaaggggg cgtgtggtca gtaacctgac cacacgcaaa cttatttagc
    24301 gcggagaaac ggtcacctga ctgccattgc tggccagtac gacacgttgg cccggagaga
    24361 aacgagtgtt gccttgtttc tgtaccacca tgatggtatt accatcgtct ttacgaattt
    24421 ccagctcgac accctgcgtt ttgttcattg cactctgtac gccctgacca gctacgccac
    24481 ctgcaacagc gcctgctgca gtagccagag aacgcccggt tccgccacca acagtattcc
    24541 ccaggaaacc accaagaaca gcaccgccaa ttgcaccgat aacgttggaa tcatcaccgc
    24601 cctgaatctg taccggacgt acgttaacga tggtgccata gctgacattc tgtacttgtt
    24661 tcgcttcaga agcggtataa acatcccctg acagggtgtc gttattaaca caaccgacaa
    24721 gagacagacc taccattgaa acaaccaata cgcgtttaat cattgaaaaa tctcctgttc
    24781 accatgaaac gccacgcaag catccctcat ggtcaaagta tatggcatat gtgaatccat
    24841 ggttacatgt tctaccaaat atgagcaaat cataatgaaa gtaggatcaa ccaattataa
    24901 acaaaacatt catgatgatt attgatttga agataatgtt ttactaccaa cggtaaaaat
    24961 cggtcattcc gcatggtatt cacgaaaagt ttatgtttga gtggtgcgca aacgtcagat
    25021 tgaaaaagga tgaactatga aatcgggccg ctttattggc gttatgtcag gcaccagcct
    25081 tgatggtgtt gatgttgtgt tggcgacaat agatgaacac cgggtcgcac agctggcaag
    25141 cttgagctgg ccgatcccgg tgtctctgaa acaggctgta ctggatattt gccagggcca
    25201 gcagcttaca ctttcgcagt ttggacagct tgatactcaa ctcgggcgac tttttgctga
    25261 tgcggtcaat gccttgctta aggaacaaaa cctgcaggcg agagatatag ttgcgatcgg
    25321 ctgtcacggt caaaccgtct ggcatgaacc gacgggcgtg gcaccacaca ctttacagat
    25381 tggcgataac aatcaaattg tggcacgcac cggaattacg gttgtcggtg attttcgccg
    25441 tcgcgatatt gccttgggag gacaaggcgc accgctggta cctgcgttcc atcatgcctt
    25501 gctggctcac tcaaccgagc gacgaatggt gctcaatatt ggcggcatcg ccaatctgtc
    25561 actgctcatt cctgggcagc cggttggcgg ctacgatacc ggtcctggta acatgctgat
    25621 ggatgcctgg atctggcgtc aggccggtaa accttacgat aaagatgccg agtgggcacg
    25681 ggcgggtaaa gttattctcc cactgctgca aaatatgctc agcgacccat atttctcgca
    25741 acctgcaccg aaaagcaccg gacgcgaata ctttaactac ggctggctgg agcgccattt
    25801 acgccatttt ccgggtgttg atccccgtga tgttcaggcc acactggcag aactcaccgc
    25861 cgtgaccatt tctgaacaag ttttgttgag cggtggctgc gaacgattga tggtatgtgg
    25921 tggaggtagt cgtaatccgc tactcatggc gcgtctggcg gcattactgc caggcacaga
    25981 agtcaccacc accgatgccg ttggcattag tggcgatgac atggaagcat tggctttcgc
    26041 ctggcttgcc tggcggacgc tggcgggatt accaggaaat ctgccttccg tcactggcgc
    26101 aagccaggag acggtactgg gggctatttt ccctgctaac ccgtgatatc agagttaact
    26161 gaatttttct taccgcgtct gccgttacac ttggaacgtt agggagggcg tattgccctc
    26221 cagaccagga aagtcttcgg gaaatgtcta tgaaaaaact gttactgatc tgtttgccgg
    26281 tgcttctcac cggctgtagc gcgttcaatc aactggttga gcacatgcaa accgctacgc
    26341 tggaatacca gtgtgatgaa aaaccgttga cggtcaaact gaataatccg cgccaggaag
    26401 tcagttttgt ttacgataat caactactgc atctcaaaca gggcatttca gcgtctggtg
    26461 cacgttacac tgacggaatc tatgttttct ggtcgaaagg cgatgaagcg actgtctata
    26521 aacgcgaccg catcgtattg aataactgtc agttacaaaa tccacagcgt tgagattttt
    26581 ccaggggcgg cgcacaatag cgtcacccac tgacaatccg taaagaaaac catgtctgat
    26641 aacgacgaat tgcagcaaat cgcgcatctg cgccgtgaat acaccaaagg cgggttacgc
    26701 cgtcgcgatc ttcccgccga tccattaacc ctttttgaac gttggctctc tcaggcgtgt
    26761 gaagccaaac tggcagaccc taccgcgatg gtggtcgcta ccgtggatga acatgctcag
    26821 ccttatcaac gcatcgtttt actcaaacat tacgacgaaa aaggcatggt gttttacacc
    26881 aacctcggta gccgtaaagc acatcaaatt gaaaataatc cgcgcgttag cctgctgttc
    26941 ccgtggcata cccttgaacg ccaggtgatg gtgatcggta aagcagaacg actttcgact
    27001 ctcgaagtga tgaaatattt tcatagccgc ccgcgtgata gccagattgg tgcatgggtt
    27061 tcgaagcagt ccagtcgcat ttctgcccgc ggtatccttg aaagtaaatt cctggagctg
    27121 aagcagaagt ttcaacaggg cgaagtgcca ttgccgagct tttggggcgg ttttcgcgtc
    27181 agccttgaac agattgagtt ctggcagggc ggtgagcatc gcctgcatga ccgctttttg
    27241 taccagcgag aaaatgatgc gtggaagatt gatcgtcttg caccctgaaa agatgcaaaa
    27301 atcttgcttt aatcgctggt actcctgatt ctggcacttt attctatgtc tctttcgcat
    27361 ctggcgaaaa gtcgtgtacc ggcaaaggtg cagtcgttat atacatggag attttgatgg
    27421 caagcagtaa cttgattaaa caattgcaag agcgggggct ggtagcccag gtgacggacg
    27481 aggaagcgtt agcagagcga ctggcgcaag gcccgatcgc gctctattgc ggcttcgatc
    27541 ctaccgctga cagcttgcat ttggggcatc ttgttccatt gttatgcctg aaacgcttcc
    27601 agcaggcggg ccacaagccg gttgcgctgg taggcggcgc gacgggtctg attggcgacc
    27661 cgagcttcaa agctgccgag cgtaagctga acaccgaaga aactgttcag gagtgggtgg
    27721 acaaaatccg taagcaggtt gccccgttcc tcgatttcga ctgtggagaa aactctgcta
    27781 tcgcggcgaa caactatgac tggttcggca atatgaatgt gctgaccttc ctgcgcgata
    27841 ttggcaaaca cttctccgtt aaccagatga tcaacaaaga agcggttaag cagcgtctca
    27901 accgtgaaga tcaggggatt tcgttcactg agttttccta caacctgttg cagggttatg
    27961 acttcgcctg tctgaacaaa cagtacggtg tggtgctgca aattggtggt tctgaccagt
    28021 ggggtaacat cacttctggt atcgacctga cccgtcgtct gcatcagaat caggtgtttg
    28081 gcctgaccgt tccgctgatc actaaagcag atggcaccaa atttggtaaa actgaaggcg
    28141 gcgcagtctg gttggatccg aagaaaacca gcccgtacaa attctaccag ttctggatca
    28201 acactgcgga tgccgacgtt taccgcttcc tgaagttctt cacctttatg agcattgaag
    28261 agatcaacgc cctggaagaa gaagataaaa acagcggtaa agcaccgcgc gcccagtatg
    28321 tactggcgga gcaggtgact cgtctggttc acggtgaaga aggtttacag gcggcaaaac
    28381 gtattaccga atgcctgttc agcggttctt tgagtgcgct gagtgaagcg gacttcgaac
    28441 agctggcgca ggacggcgta ccgatggttg agatggaaaa gggcgcagac ctgatgcagg
    28501 cactggtcga ttctgaactg caaccttccc gtggtcaggc acgtaaaact atcgcctcca
    28561 atgccatcac cattaacggt gaaaaacagt ccgatcctga atacttcttt aaagaagaag
    28621 atcgtctgtt tggtcgtttt accttactgc gtcgcggtaa aaagaattac tgtctgattt
    28681 gctggaaata atgcattaag tggaaagggg gagtgagaaa tcactccccc tggtttttat
    28741 acagggaaca tgatgaaaaa tattctcgct atccagtctc acgttgttta tggtcatgcg
    28801 ggtaacagtg cggcagagtt tccgatgcgc cgtctgggcg cgaacgtctg gccactgaac
    28861 accgttcaat tttctaatca cacccaatac ggcaaatgga ctggctgcgt gatgccgccc
    28921 agccatttaa ccgaaattgt gcaaggcatt gccgccattg ataaattaca cacctgtgat
    28981 gccgtgttaa gtggctatct gggatcggcg gagcagggtg aacatatcct cggtatcgtc
    29041 cgtcaggtga aagccgcgaa tccgcaggcg aaatattttt gcgatccggt aatgggtcat
    29101 ccggaaaaag gctgtatcgt tgcaccgggt gtcgcagagt ttcatgtgcg gcacggtttg
    29161 cctgccagcg atatcattgc gccgaatctg gttgagctgg aaatactctg tgagcatgcg
    29221 gtaaataacg tcgaagaagc ggttctggca gcgcgcgaac tcattgcgca agggccacaa
    29281 attgtgttgg ttaaacacct ggcgcgagct ggctacagcc gtgaccgttt tgaaatgctg
    29341 ctggtcaccg ccgatgaagc ctggcatatc agccgtccgc tggtggattt tggtatgcgc
    29401 cagccggtag gtgttggtga tgtgacgagc ggtttactgc tggtgaaact gcttcagggg
    29461 gcaacgctgc aggaggcgct ggaacatgtg accgctgcag tctacgaaat catggtgacc
    29521 accaaagcaa tgcaggaata tgagctgcaa gtggtggctg ctcaggatcg tattgccaaa
    29581 ccagaacatt acttcagcgc aacaaagctc tgaaatatct catttcggcc cacaacgacc
    29641 tgtgggccga tggatattac tttaagcctt ccgctgacag cgcgtcttgt acttccggac
    29701 gttcagccat acgttgcata aatgctgcaa tgtgctctaa cccttccaga ttcagtttca
    29761 ccgcgtatgc ccagcgcaga accgtaaaca gataggcatc agcaattgta aatctttgcc
    29821 cgcagatcca gtgctcatcc ttcagtgcct cgttcacata ttgcagcttc ttctccagct
    29881 gcgcgcgaac tgtcggtttg tactcttccg gtgtatcagg gcgaaacaga ggtgtgaaac
    29941 ctttatgcag ctcggtggcg atgtaattca gccattcgat ggttttatag cgggaaatac
    30001 tgtttaccgg tgccagcaac tggcggtcgg ggacgctgtc ggcaagatac tgcataatcg
    30061 ctacgccttc cgtcagcaaa gtaccgtcat ccagcagcaa tgcaggcacc tgccccttag
    30121 ggttaacgac aaagtaatcg tcaccgtttt cgagacgttt tttcattaaa tccacactga
    30181 cgagggtaaa atcctttccg ctctcacgca gggtgatatg ggaagcgaga gagcaggcac
    30241 ccggtttgta gaacaatttc atcggtaact ccttttgtct gtggtttaaa gtatggtagt
    30301 gcgttgctga acaaaaaaaa agccgctaac gaaaagttag cggcttgtaa aagagtttcc
    30361 ctgaatttta cgctacagca gctttcgccg ctttgtctgc agcgtcatcc tgcgtcatac
    30421 ggtgcagttt aggcgcggtc agcagcatca gtactgcaat aatggcagta gcgacaccaa
    30481 tctgcaagaa tacgcgacca taaacttcca gtgacatcag cgggtcggta acgttatccg
    30541 gcacagccat catacccgca acataaccac caatcaggtt tgcaccggca gtggtcagga
    30601 accagctacc cataatgaag cccatcagac gctgcggaac gagttgtgca accattgcca
    30661 gacccagacc agagatcatc agttccccga tgctctgcag gccatagctt gcgaccagcc
    30721 agcttacaga cacgatacca gcgtcagacg cgaatttcgc acccagcggc agaatcagga
    30781 acgcaccaga acacatcacc atgccgattg caaacttggt tggcatcggc agggtatcgc
    30841 ccatcttgtt atagatagcg gccagaatcg gactaccgat gatgatccag aacgggttca
    30901 gtgcctgata ctgctcaggt tctacggcca gacccagaat ggagtgctca acgttacgaa
    30961 tcgcaaagaa gttcagtgac gttggcatct ggctgtacag cacgaagaag ataatggctt
    31021 cgagcatcag gatgaaggca acgatcattt tacgacgcgc agcacctttc atcgcgaagg
    31081 cttctttacc gaagataacc acgataccga aggcaacaac gcccagcgcc atacgcgcaa
    31141 cttcctgatt gtgcagcagc caggtggcga tagcgatcag tgccacaaca ccaataatgg
    31201 tcagcagcag gttacggtag ttgataggct cgaagtctgg ttttgaaccg tactgtttaa
    31261 cccagcgttg gcagaaggcg aagttaacga tagtgatcag caggcctaca acgctcaacg
    31321 caaacgcaac actccagccg tatttcgcgg ccagccacgg cgtagcaatc atagagaaga
    31381 aagagccgat gttgacggac atgtagtaca tggtgaatgc accgtccaga cgcgggtcgt
    31441 ttttctcata gcatgtagaa agcagagaag acgggttagc tttaaacagg ccgttaccga
    31501 ccgcaatagc cgccataccc atataaacga taccggcgtc gtgaccagac caggcaacca
    31561 gagcataacc aatcgccagc acaatagcgc cgagcataat tacgcgttta gtacccagta
    31621 ccttgtcacc taaccagccg ccgatagcga ccagaccata aaccagggca ctaaaggaag
    31681 agaaaagggt gattgaatcc gcttcagaca tacccagttg tttaaccagg taaacagcca
    31741 taattccttg taggccgtaa taaccaaaac gttcccataa ctcaatcgag aagatgagat
    31801 agaacgcctt cggttgtttg aaagcgttca aactgacgct ttcagttggt ttttggtttg
    31861 cagtggacac ttttacctct ttttttacat cccatattaa cgggggtgct ttctcgcgtt
    31921 atgtctaaaa aacatacgcg caattgttat agtgggaggg gaaacggcag gtaatgttca
    31981 ctatcttgca ctttcagaca agtcctttgt aataatctgt tacatataac tgaggcgggg
    32041 aattcaacca ttccgggaaa tgttatccag cgttaaattt ttcaaaaaac gtaacggcag
    32101 attttttcac tgcactgaga ggggggtgat ggcttaacgg cgatatgttc tgctatttag
    32161 cgtttttact agtgagatag tccagtttct gaaaaatagc cagtgtaatg ttttgtaggt
    32221 caatatttgt tgcgtgtgta aatttaaatg attttaacct gattcttgca atgtttttac
    32281 attgcgacag catcgtgatc ttgatcacga atgaatagaa aatttcgcta ttaaaaaaac
    32341 aattaacctg catttttggt tatccgcaaa cggattacct gatgataacg ctaagcaatg
    32401 gcatcattca cgttaaaaag atgttttaaa agaggataaa gaaaggttat caatggggta
    32461 atcggtgtta ccccttttct tcagatgtca actttctctt tgtattcaca aagatcttca
    32521 ataatacaag agccacagcg gggcttgcgg gcaatgcagg tataacgccc gtgcaggatc
    32581 aaccaatggt ggcagtcgac tttaaactct gccggaacca ctttcagtag cttttcttct
    32641 acctgttcga cgtttttccc cggcgcaaat tgagtacgat tacaaacgcg gaaaatgtgc
    32701 gtgtcgacag caatagtcgg ccagccgaat gcagtgttta atacgacgtt ggctgtttta
    32761 cgacctacgc cgggcagggc ttcaagcgca gcacgatctt ccggaacctc gccattatgc
    32821 tgctccagca agatacggca ggttttgatg atattttctg ctttgctgtt ataaagccca
    32881 atcgttttga tataggtttt caccccttca acgcccagtt caagcatcgc tgcaggcgta
    32941 ttcgccaccg ggtagagttt cgccgtcgcc ttattaacac tgacatcggt cgcctgagcg
    33001 gaaagcagta cggcaatcag caattcaaaa ggcgaactga aattaagctc ggtggtggga
    33061 tgaggattgt tctcacgcag gcgagtgagg atctccaggc gttttgcttt gttcatcaga
    33121 cattccctgt ttcaccgttt ggcaatgcac gttcggcagt tgcttcagca cggcgctttt
    33181 tcattctttc atcaatcagg tattttcctg ccagcatcag tcccaggcca ataaatgcac
    33241 ctggaggcag catcgccagc aggaaagggg agtcggtgtg gaaaatttcc acgcgtaata
    33301 cttttgccca gctacctaac agcgcatctg caccgtcaaa caatgtgcca ttgccgataa
    33361 tttcgcgtag tgaacccagc acgaacatgg cgcaggttgc gcccatacca attgaaaagc
    33421 cgtccagtgc cgaaagcgcc ggaccttttt tggcggcgaa ggcttcagcg cggcccacaa
    33481 cgatacagtt agtgacaatc agcggaataa aaatccctaa tgattgatac aggccaaagg
    33541 cgtaggcgtt gatcagcatc tgtacagcgc tgaccaccga ggcgatgatc atcacgtaaa
    33601 tgggaatgcg gatctcggct ggcgtccagt gacgcagcgt cgaaatggtc aggttggtca
    33661 gcgtcagtac cagcgtagtc gcaagtccta aacccagagc gttagtggca gtggacgtga
    33721 ccgccaacag aggacaaagg ccgagcaact ggaccagcgc agagttgttt ttccacaacc
    33781 cctgaacaat aacgtcttta atttcgctca cgctttattc tccacaggca ggaagttgag
    33841 aaagttgtgc cggtaacgtc tgagcgtaca atccggcgcg ttttaccgca ttaaccaccg
    33901 cgcggggagt aatcgtcgcg ccggtgaact ggtcgaaatc accaccatct ttcttcaccg
    33961 cccagtgcgc atcatccgca ccactgattt ttttacccgc aaaatgggtg atccagtcag
    34021 aaaggcgcag ttcgatttta tcgccaagcc ctggcgtttc gtggtgctct gtcacgcgcg
    34081 tgccaagtac cgtgccgtta aaatcggctc ccaccagcag ctgaatcgca ccggaatagc
    34141 catctggcgc ggttgcttcc agaacggcgg ctaccggttt gtcatcctgt ttggcgatgt
    34201 aaacccgatg ctcaccttta cctaactctg gcgcagttac cagatagcaa ctctgtgcca
    34261 gcgcattgtt atagcgttcg gctggcagca cctgatcaaa taatgcctct tgttgcagac
    34321 tggcctgttc agcaatcgtc gttttggtca tctggttgat ggccgcagtt aaccctgttg
    34381 aacccgctgc aaatagcgct aacgtaatgc cgtgttttcg gatagttttc agcatggttt
    34441 accctttgcg atggccgtag acgcgcggac gcgtgtagta atcgatcaga ggaaccgtga
    34501 tgttcgccag caggacggca aaagccacgc cgtcaggata gccgccgaaa ctgcggatca
    34561 accagactaa taagcccgcc agcgcgccga aaataagacg accacgattg gtcgtagaag
    34621 cggtaaccgg gtcagtcaaa ataaagaatg cgccgagcat ggtcgcacca gacagcagat
    34681 gaatttgcgg tgctgccagt gtttctggtg agaacaacca gcccaacgtt gcgcataacg
    34741 ccagcgttac taagaagctg aggggaatat gccagcgaat cgctttctgc catagcaacc
    34801 acaggccgcc agccagccag gcgagattta cccattgcca accagcgccc gccagaatac
    34861 cgctgtagat cggatattgc ataatctgtt caaccgaatg accggcacgg acagaggttt
    34921 taaatgtatc cagcggtgtc gcctgactaa tgccatcaat acctaagcgt agtgtgttca
    34981 tatcaccacc actggcggta tgtccgctga aaataacctg tatggcgtcg ataaaaccag
    35041 ggatgttgac cgcaatttca tgtggcggta accagctggt catctgcacc gggaaggaga
    35101 tcagtaagac cacataacca atcattgccg gattaaacgg gttttgcccc agaccgccat
    35161 acaactgttt agcgatgatc accgcaaaca ccgtacccag cacgaccatc caccatggcg
    35221 cgaggggggg aatacttacc gccagcaata agcctgtcag caatgctgag ttatctttca
    35281 acgttgcggc taccgactgc ttgcgtagtt tgagtacgag agcttcggct aacagagcac
    35341 taaccgatgc caacaggatc tgaacgagag taccccaacc aaaaaaccac agttgcgctg
    35401 cgattcctgg cacggctgcg agcaacacca acagcataat gcgcgatgtc tggcgctggt
    35461 tatgggtata aggggagcta gctattctga ataccattta gtcctcgttt acaaccttct
    35521 gctgggcggc ttttttggcc tgagcgcggg caatagccgc ggcaactgcc gctttgcgcg
    35581 gatcaacctg ttcttctggt tctgcgttag tctgttgctg ttccagcttg cgcgctttgg
    35641 cacgggcaat agcggcttcg acggcggctt tgcgcggatc aacctgttct tctggttccg
    35701 cattagcctg ttgctgttcc agtttgcgcg ctttggctcg ggcaatagcg gcttcgacgg
    35761 cggctttgcg cggatcaacc tgttcttctg gttccgcatt agactgttgc tgttccagct
    35821 tgcgcgcttt ggcacgggca atagcggctt cgacggcggc tttgcgcgga tcgacctgtt
    35881 cttctggttc cgcattagcc tgttgctgtt ccagcttgcg cgctttggcg cgggcgatag
    35941 ctgcttcaac ggcagtttta cgtggatcag caacggttgc tgcgtcgtta gtttgctgca
    36001 gttctgcctg tttcgctctg gcttgcgctt tacgggcttc ccgtgctgca ataattgcac
    36061 tgttatccgg gcgttcgccc gctttaatca caataggctg tgtagcctgg gcctgtttct
    36121 ctttcacccg cgccagagcg gcagcaatcg catctttatc tttggctgca ggttgaacgg
    36181 ctgcgctctt atgtcgttca aggcgagccg ctttttcgcg ctccagacga gcctggcgcg
    36241 cttcgaaacg cgctttggct tctgcggcgc gcttttcttc ctgacgaata gccgcaattt
    36301 cagctttttc ctgacggaaa tattgcacca ggggaatatt gctcgggcaa acccacgcgc
    36361 aagccccaca ttcaatgcaa tcagcaatgt tatgcgtggt agctttatcg tgttgctgac
    36421 ctttgctgaa ccagtacaac tgttgcggca aaagatccgc agggcaggcg tcagcacagg
    36481 cgctacaccg gatgcagctt tgttcttcct gtggttcgcc aagttcattg gcagagggag
    36541 ccaacagaca gttggtaatc tttacgaccg ggacatccag ccatggcaag gtaaagccca
    36601 ttagcgggcc acccataatc accatttgat cggcagaggg gcagaatccg gcatcattca
    36661 ataaatgacg cactggcgtc cccagccgtg cccagacgtt gcccgggcga gcgattgctt
    36721 cgccagtcag ggttacaaca cgctcggtaa tcggctcgcc atcaataacg gcacgtttca
    36781 ctgcataagc agtgccgacg ttttgcatta atacgccgat atcggatgaa cgcccgccat
    36841 gtggaacctg cttcccggtc agaatgtagg ttaattgttt agcaccgcca gaaggatatt
    36901 tggttggaat cacccgcaga gaaatatcgt tagagtccgc cagcaccgcg cgcagcatgg
    36961 aaatcgcctg cggtttgtta tcttcaatgc cgataagaat ttcgcgtggc tgcagaatat
    37021 gcgcaagaat gcgaataccc tctacgacct gagccgcgca atcctgcatc aaacggtcat
    37081 cggcggtaat gtacggctcg cactcagccg cgttgataat caacgtttca atcttatctc
    37141 cgccaccctg caatttaacg cctgtcggga atcctgcacc gcccagcccg gctacaccaa
    37201 actgatgtat gcgctcgatt aactcttcgc gactgcgagt gcgataatcg gcccagccgt
    37261 cgcgcgggat ccagcagtct tcaccatcgg catcaataat cacgcttaat tcagctaaag
    37321 ctgaaggatg agccgtagag tggggcgcaa tagccgtaac ggtacccgag gtgggcgcgt
    37381 gaacaggcag cattttgccg cgaccacggg taagcggctg gccgcgcaat actttatcgc
    37441 cgacgctaac gcacaactca ccttcagcgc caatatgctg tttcagtgga ataacaaaac
    37501 gctgcgccag tggtacctgg cgcaggggtg taccgttgga ctgggttttc atctccggtg
    37561 gatggatgcc gccgttgaaa tcccagattt tattttttct gaatgcagag aataacttaa
    37621 gcatggtgtt ccacgggaat gatacgcacg ggaatggtgt tcagatccca tttccaggag
    37681 tcaggtgttt ctgcgaccgg ttgcaacgag atgcagtgcg tcgggcacgg atcaacacat
    37741 aaattgcagc ccgtacagag atcactcatt accgtatgca tggcacgggt agcgccaacg
    37801 atggcgtcta ccggacaagc ctgaatacat ttagtgcagc caatacagtt attttcatca
    37861 ataaccgcca ccatccgcgc aggcgttagc tcttgcgctt cgccatccag cggctgcggc
    37921 tcgacattaa gcaactcggc aatttttagc atcacagctt cgccacctgg ggcgcaacgg
    37981 ttgatttttt caccgttaca gctgatggct tccgcgtagg ggcgacagcc gggataaccg
    38041 cactgaccac actggctctg cggtaagatt tcgtcaattt tctcaacgac cggatcgtct
    38101 tccaccgcaa aacggcggga ggcataaccc agaatggcgc caaacgccag gcccagcagg
    38161 ctcacggcgg caacggcaat ccagatagca ttcattacaa cttcaccaaa ccactaaagc
    38221 ccataaaggc cagagacata agacctgcgg taattaacgc aatggcatta ccgcgaaaag
    38281 gtgccgggac atcagccaca gcaaggcgtt cgcggatggc ggcgaagagc accatcacca
    38341 gcgagaaacc gacagcggcg gaaaaaccgt acagcgccga ctgcaagaaa ttgtgcccga
    38401 gattgatatt cagcaacgcc acgccgagca ctgcacagtt ggtggtgata agcggcaaaa
    38461 aaatccccag cagacggtaa agcaccgggc tggttttgcg caccaccatc tcggtgaact
    38521 gcacgaccac agcaatcacc agaataaatg ccagggtgcg caggtaaatc agattaagtg
    38581 ggatcaaaat ccacgtatcg ataagccagg cgcaaataga cgccagcgtc atcacaaacg
    38641 ttgttgccag ccccatgccc atcgcggttt ccagtttttt ggaaaccccc ataaacggac
    38701 agagaccgag aaacttgacc agtacaaagt tattgaccag tacagttccg acaaacagta
    38761 acaggtagtc agtcattttt cggcctgaaa taaaaaagcc gcctattatc cgttaatcca
    38821 gagcaggcga caacaggtta actgtaaggt tattacggat tcacaaacgt cgcttttacc
    38881 cgcgacgagc gtttgaaata ggggacgatc aatgcggttg ccaacaaagt aaacagcaac
    38941 tggcgaacgg ctatgccatc ttccacgggt gaaaaagcga atgcttttac tgccagcaat
    39001 acggaaataa gcagccagat aatatagtgt ttaggaacac aacgccgacg tttaaagaaa
    39061 gcgatggtca accacagtgt gtaataccac atggcgatag cggtaataaa agaaacgccc
    39121 cataagattt gtgtcgtcag tgcttgtccg ccgagcgttt gaaatgtttg cggagaagat
    39181 aacgcagcgg tatacagcaa caacgccagc gtcgtactca acagagcgac taaaagccag
    39241 gccaacgggc caagcaacca gcctccaata cgttgtggcg ttgtggtggt cataggttct
    39301 ccagaatagc gacgcaaaca ggcaaatcta attttagggg cgttattata aggcttttat
    39361 aaccgatcgc tactttcttt attggacata gtgccagacg gacttcggta cctggccgag
    39421 gtcaaacaaa cgcccgccag aaaccagctc tgcgcgacgg tgatcggcag cacgatacat
    39481 attgatcagt tcctgatcgt ccgtcagggt gtaattaaga tggtcgtaga gtttttccag
    39541 actttcgagt gaactgattt tgcgaaattt taataagtag tcctgaacag tcataaaagg
    39601 tccataaaat aattaatacc aaaggggtag gtattattag tgatgataaa atttcaccaa
    39661 aagtgaacgc ttgtgttatt acaataataa gaatgcgctg atggcaaata ttcagggatg
    39721 aaaaactgct ctgaaaagag taacgcgctt tactatccct gacaatcacc aacaacatcg
    39781 aacaagataa taaattcctg gtttaatatc cgacaagtga aaacatgcac ccggacgggc
    39841 agcatgtcgc tccacaagtg cagagcttac ttgtgttgta ccgaagcact ctgttcaggt
    39901 ggctgatagt tgtcaatgtg actcgccacg ccaagaagaa tgactgaaac gacaagaacg
    39961 atccaacctg ttaattcaat aagacgattc attacagccc acatctctct tgattgatcc
    40021 attaacttca gggggtaaat gttacttagc aataatagct ccagcaagat ttttactgag
    40081 gtttttgcga tatttagctt ttgtcgttgg aaaattcgct atttttttga cttaagttaa
    40141 acaacatccc ttattgctgg caggttatta aactgttgag cgtgggtaaa ggatagtgtc
    40201 aaatagccat catacttcaa tgagaggcaa tgacatgagc gacaacatcc gtgttgggtt
    40261 gattgggtat ggttatgcga gcaaaacctt ccatgcgccc ctgattgcgg gcacgcccgg
    40321 gctggaactg gcggtaatct ccagcagtga tgaaacaaaa gtaaaagccg actggccaac
    40381 ggttacggtt gtctctgagc cgaagcatct gtttaacgat cccaacatag acctgattgt
    40441 cattcctaca cccaacgata cccatttccc gttagccaaa gcggcgcttg aggcgggtaa
    40501 acatgtggtc gttgataaac cctttaccgt gacactgtca caagcgcgag agctggatgc
    40561 gctggcaaaa agcctggggc gtgtgctgtc tgtattccat aaccgtcgct gggatagcga
    40621 tttcttgacg ctaaaaggtt tactcgcgga aggcgtgctg ggtgaagttg cttactttga
    40681 gtctcatttt gaccgcttcc gtccgcaggt gcgcgatcgt tggcgtgaac agggcggccc
    40741 aggcagcggt atctggtacg atttagcacc acatcttctt gatcaggcca ttacgctttt
    40801 tggtttaccg gtcagcatga cggtagattt ggcacagtta cggcccggag cgcagtcgac
    40861 cgattatttc cacgccatct tgtcctatcc acagcggcga gtcattttac acggtaccat
    40921 gctggcagcc gctgagtcag cacggtatat cgtgcatgga tcccgaggca gttatgtgaa
    40981 atatggcctc gatccacagg aagaacgtct gaaaaatggc gagcgtctac cgcaggaaga
    41041 ctggggctac gatatgcgtg atggcgtact tacccgcgtg gaaggtgagg aacgtgtcga
    41101 agaaacgctg ttgacggtgc ctgggaatta tccggcttac tatgcggcta ttcgtgatgc
    41161 gttaaatggc gatggtgaaa atccggttcc ggcaagccag gcaatccagg taatggagtt
    41221 gattgagctg ggcatcgaat ccgccaaaca tcgcgcgact ttgtgccttg catgaaaaat
    41281 ggatggtgca atttgcacca tccattttgt tacttcgcgg cgactttttc tcgcagtgcg
    41341 cgtttttcct cagcgctgag gaaagccatt tccagaccat taatctgtgc ctggcggatt
    41401 tgctcgcggg ataacccagc agctggcgcg gcaacggtat attcgtgaat gatatccact
    41461 ccctgtacgc cgggatcgtc agtgttaatg ctggcacgaa tgccatgctc aaggaacgtt
    41521 ttcagcggat gtgcagccag ctctgctacg gtgctggtct gaatattgga ggtcagacag
    41581 gattcaatac caatttgttg ctcggcgaga aaatccatca gcgcccgatc ttcaatggct
    41641 tttacgccat gtccaatacg ctccgcaccc agttcacgaa tcgcctgcca gatgctttcc
    41701 ggcccggcag cttcgcctgc atggacggta atatgccagc ccgcatcacg cgcgcggttg
    41761 aagtgagaaa ggaacagact tcccgggaaa ccaagttcat caccggctaa atcaagtgcg
    41821 gtaatctggt cacggtgggc taaaaaggcc tccagctctt gctgacaggc ggcttcgccg
    41881 aaggtccggc tcataatgcc gataagcttc gcctgcacac caaaggtgcg gcaaccttca
    41941 cgtacgccat cgatcaccgc ttcgacaaca cccgctacag gcagctgatg tgccattgcc
    42001 atgtagcctg gtgaaaaacg cagctcgaca tagtgcaggc cgtgacgggc tgcatcttca
    42061 atgttttcaa atgccacgcg gcgacaggca tcaagagagg cgagaacttt aacgccccag
    42121 tcaagtttgg tcagaaagct caccagatcg ggttcgttgg caatgacctg aacgtgggga
    42181 atcagtgttt ccagggattg tgcaggaagc gagatattat actggcggcc aagttcaaga
    42241 atggtctggg gacgaatgtt gccatcaagg tggcgatgga tatcagttaa tggcagggtg
    42301 gtatcaatca tggtcgcact ctttttctga atataaaagt gcgcaccatt ataaaaacaa
    42361 agcagggtaa aaatccacga ttgcgcaacg attttttacg ttgcgcaatt ggggttagcg
    42421 aacagcgcgg atggcgttta ttaatccagc cacacctttt tccagtttcg aacgtgggca
    42481 gccggcattg agacggacaa aaccacgacc ttcttcacca taggtatacc ccggcatgat
    42541 cgcgactttt tcttgctcga taagcgcttt ttgcaacgcg ttgtcgtcaa tattcaacgg
    42601 acgtagatca agccaggcca gataagtgga ttgcgggatc tgccagttga gttcaggaaa
    42661 cgcggcgttc attttatctg agatatacgt caggttatct ttcagataga ctcgtaaggc
    42721 atccagccac ggtgcacctt gctgataggc ggcgatatgg gcagttaacg ccagtaccga
    42781 aggggaagaa agcccatcac gtcctttcag tgccgataaa taggcatcac ggctgctgct
    42841 attttctata atcccgtaag caccggtcag cgcgggaata ttgaaacttt tcgagcccga
    42901 cgtcagcaac gcccagtctc cccgcgccac attactccag ggaatatgcg gctgctcgcc
    42961 ccagaccata tccatatgga tttcatcgga aataacccgc acaccatgac gctcgcacag
    43021 gtcagccatg atctccagct catcgcacgt ccacactttc ccggtaggat tctgtgggct
    43081 acacaggagc ataattttac attctggttt cgccaacacg gcttccagct tgcccatatc
    43141 gcaaaaccag tcgtcagcct gcttctctaa agcaacgggc attactgtgc gctggttacc
    43201 ttcaatggcc ttgtaaaatg cgtcataggc gggcgtgtgg atcaccacgc cttcacctgt
    43261 ttcagaccac tgacgaatca gttctgaaac catatagatg acagaagggc catacaccac
    43321 cgtctgcgta tcaattgcgg tgtaatgctg ggtggaaaac cagtgggcaa tagccgcgag
    43381 aaactcatcg tttttccagc ggctgtagcc aaatacgccg tgcatcaggc gctgattcag
    43441 cgcctcgata atgcaggggg cagtggcaaa atccatgtct gaaatcgtga acggtaacag
    43501 gtcagcagtg ccgaaacggt cagcgacata atcccactgt gtacaccatg tgccatgacg
    43561 atccacgacc tttgaaaaat cgaacatatc ttatccttat gcctggacag tatgcatcag
    43621 accggccatt tcatctttta ctgactgaac ttgtggcccg ataacaacct gcaggttatg
    43681 ttgattaagt tgtactacgc caattgcccg attgtccttc agtgcctgca cattaacaag
    43741 cgacatatct ttcacagaca aacgcagacg ggtaatgcag ttatcgaggc tgacaatatt
    43801 gtcggcaccg cctaatgctt cgaggattgc aggaacgttg taacctgatt tacccggcgc
    43861 accggcaacg gctttttcga ttgagctggc aacttcgcta tcgcgccccg gggttttcag
    43921 attgaagcgg gtgatagcga aacggaagat gacgtagtaa acgacaaacc agattgccgc
    43981 caccactggc accatgtacc acttggttga cagaccatgc aaaataccga acaccacgaa
    44041 gtcgatgata ttgccgtcgg tattaccgat ggtgacgccg agcacagaca tgacagtgaa
    44101 gccgaggccg gttaacagcg cgtggatgac atacagaact ggcgccacga acaggaacag
    44161 gaattccagc ggttcggtcg tgccgccaac gacacaggcg atcaggccag aaatcagcag
    44221 acctttaatt ttatggcgat tttccgggcg cgcgcagtga tacatagcta acgctgcacc
    44281 tggcagaccg ccgagaaacg caggcatttt accttgcgaa aggaaacgcg tggcgctttc
    44341 agaaaaaccg tgagtggtcg ggcaactcaa ttgcgcctgg aagatggtca gtgcgccgct
    44401 gacggtttga ccgcagactt cctgcgtgcc gcctgcgtcg gtaaagcgaa ttaatgccac
    44461 cagaatgtga tgcagaccaa acggcaacag cagacgttca ccggtaccaa acagcatcgg
    44521 tccgaaatca cccgcgctgt ttatcatatg gcccaagccg ctaataccca tggcgaaaat
    44581 cggccagact aatggaatca ccaggccgat aaggcccatc accagcgagg agataattgg
    44641 tacgaagcgc gtaccgccga agaatgccag cgcatccggc aggcggatat tatggaaacg
    44701 ctcatgcagc atccagacga taataccggc gatcaccgca ccgaggatcc cggtatcgat
    44761 cgactggatc ccaagaatgc tctggatgtt attggctttc agaaccgcgg catccgtggt
    44821 tggcataatg cctttattgg tcaaccagaa gtttaccgcg aggttcatta ccgcataacc
    44881 gacgaagcca gcgaatgccg ctacgccttt attttcgcgt gccaggccca gcgggatggc
    44941 gatacagaac atgacaggca ggaaactaaa agcaaacgag ccaatcttac tcatccaggt
    45001 aaagatagcc tgcaacacgg ggttgcccag gaccgggatc agggttatga catcatggct
    45061 gctaagagaa ctaccaatgc cgagcataat gccgcagaac gacaataatg ccacgggtaa
    45121 catgaaggtt ttgcctaact gctggaagaa ctcccacagc gtgactttcg gtgctgtttt
    45181 cgccgtcata aaacgactcc tcgtagagaa caatctggat tcagtaaatt gcgcgagaag
    45241 ataaaacgtt ttatcaaatt ttagtgaggc ataaatcaca ttacgcaacg ataatagcgg
    45301 gtataagata aataaaaggt aaaacgtttt atctgtcaca taatcaggga gtaggtcatc
    45361 tgcatggcta ccgccaaaaa aataaccatt catgatgttg cgctggctgc gggcgtgtcg
    45421 gtaagtaccg tttcgctggt gcttagtggc aaagggcgaa tctctaccgc cacaggagaa
    45481 cgcgttaacg ccgccattga agagctggga tttgtgcgca atcgccaggc gtcggcgctg
    45541 cgcggcgggc aaagcggcgt cattggtttg atcgtccgtg atttatctgc gccgttttac
    45601 gccgaattga cggccggatt gacggaagct ctggaagcgc agggacggat ggtttttttg
    45661 cttcacggcg gtaaagacgg cgagcagctg gcacagcggt tttcactgtt actgaatcag
    45721 ggtgtggatg gtgtggtaat tgccggggct gcaggaagca gcgatgacct gcgacggatg
    45781 gcagaagaaa aagctatccc ggtgattttc gcttcccgtg ccagttatct tgatgatgtt
    45841 gatacggttc gcccggacaa catgcaggct gcacagttgt tgacggagca tctcattcgc
    45901 aatgggcatc agcggatcgc ctggctggga gggcaaagtt cctcattaac ccgtgcagaa
    45961 cgggtggggg gctattgtgc aactctacta aaatttggcc tgccgtttca cagcgattgg
    46021 gtgctggagt gcacatccag ccagaagcaa gccgcggaag ctatcacggc gcttttacgt
    46081 cataacccga ccatcagtgc tgtggtttgc tataacgaaa ctattgcgat gggggcatgg
    46141 tttggtttgc tcaaagcagg gcggcaaagc ggggaaagcg gagtcgatcg ttactttgag
    46201 caacaagttt cgctggcggc atttaccgat gcgacaccaa ccacacttga tgatataccc
    46261 gttacctggg ccagcacgcc tgcgcgggaa cttggtacca cacttgcgga tcgcatgatg
    46321 caaaaaatca cccatgaaga gacgcattca cgcaatctta ttattcccgc ccggctcatt
    46381 gcggcgaaat aatcctctct ttatctgcta tacctggtag tgtcctttcc tcaaggttaa
    46441 tgataaaaaa tgtggcacac aggcggtgcc ttttattttt actgaagttc acaggaggtt
    46501 tatgtgttta attctgacaa cctgagactc gacggaaaat gcgccatcat cacaggtgcg
    46561 ggtgcaggta ttggtaaaga aatcgccatt acattcgcga cagctggcgc atctgtggtg
    46621 gtcagtgata ttaacgccga cgcagctaac catgttgtag acgaaattca acaactgggt
    46681 ggtcaggcat ttgcctgccg ttgtgatatt acttccgaac aggaactctc tgcactggca
    46741 gactttgccg tcagtaagct gggtaaagtt gatatcctgg ttaacaacgc cggtggcggt
    46801 ggtcctaaac cgtttgatat gccaatggca gattttcgcc gtgcttatga actgaatgtg
    46861 ttttcttttt tccatctgtc acaacttgtt gcgccagaaa tggaaaaaaa tggcggtggc
    46921 gttattctga ccatcacttc tatggcggca gaaaataaaa atataaacat gacttcctat
    46981 gcatcatcta aagctgcggc cagtcatctg gtcagaaata tggcatttga cctgggtgaa
    47041 aaaaatattc gggtgaatgg cattgcgccg ggggcaatat taaccgatgc cctgaaatcc
    47101 gttattacac cagaaattga acaaaaaatg ttacagcaca cgccgatcag acgtctgggc
    47161 caaccgcaag atattgctaa cgcggcgctg ttcctttgct cgcctgcagc cagctgggta
    47221 agcggacaaa ttctcaccgt ctccggtggt ggggtacagg agctcaatta atacactaac
    47281 gaaccggtaa acagccgtat gtgttgttta ccgggatagc gtgtgcaatt catcaacgtc
    47341 tctgctaaac aactggcagc caaatcacgg ctattggtta accaatagat ggatgaaaag
    47401 catacgaata gagtgtgcct tcgcactatt caacagcaat gataggcgct cacctgacaa
    47461 cgcggtaaac tagttattca cgctaactat aatggtttaa tgatggataa catgcagact
    47521 gaagcacaac cgacacggac ccggatcctc aatgctgcca gagagatttt ttcagaaaat
    47581 ggatttcaca gtgcctcgat gaaagccatc tgtaaatcct gcgccattag tcccgggacg
    47641 ctctatcacc atttcatctc caaagaagcc ttgattcagg cgattatctt acaggaccag
    47701 gagagggcgc tggcccgttt ccgggaaccg attgaaggga ttcattttgt tgactatatg
    47761 gtcgagtcta ttgtctctct cacccatgaa gcctttgggc aacgggcgct ggtggtcgaa
    47821 attatggcgg aagggatgcg taacccacag gtcgccgcca tgcttaaaaa taagcatatg
    47881 acgatcactg aatttgttgc ccagcggatg cgtgatgccc agcaaaaagg cgagataagc
    47941 ccagacatca acacgtcaat gacttcacgt ttactgctgg atctgaccta cggtgtactg
    48001 gccgatatcg aagcggaaga tctggcgcgt gaagcgtcgt ttgctcaggg attacgcgcg
    48061 atgattggcg gtatcttaac cgcatcctga tcctctcatt tcgcgggctg gtgataactg
    48121 tgcccgcgtt tcatacttta atttccctgt acaaaataca atctagccgg gatcggagaa
    48181 ttccccccca aaaatattca ccgtagccat atgtcatgag agtttatcgt tcccaatata
    48241 ctcgaacgaa cgttcggttg cttattttat ggcttctgtc aacgccgttt taaagattaa
    48301 tgcgatcaat atcacgctgt gggtattgca gtttttggtt ttttgatcgc ggtgtcagtt
    48361 ctttttattt ccatttctct tccatgggtt tctcacagat aactgtgtgc aacacagaat
    48421 tggttaacta atcagattaa aggttgacca gtatttttat cttaatgagg agtcccttat
    48481 gttacgtcct gtagaaaccc caacccgtga aatcaaaaaa ctcgacggcc tgtgggcatt
    48541 cagtctggat cgcgaaaact gtggaattga tcagcgttgg tgggaaagcg cgttacaaga
    48601 aagccgggca attgctgtgc caggcagttt taacgatcag ttcgccgatg cagatattcg
    48661 taattatgcg ggcaacgtct ggtatcagcg cgaagtcttt ataccgaaag gttgggcagg
    48721 ccagcgtatc gtgctgcgtt tcgatgcggt cactcattac ggcaaagtgt gggtcaataa
    48781 tcaggaagtg atggagcatc agggcggcta tacgccattt gaagccgatg tcacgccgta
    48841 tgttattgcc gggaaaagtg tacgtatcac cgtttgtgtg aacaacgaac tgaactggca
    48901 gactatcccg ccgggaatgg tgattaccga cgaaaacggc aagaaaaagc agtcttactt
    48961 ccatgatttc tttaactatg ccgggatcca tcgcagcgta atgctctaca ccacgccgaa
    49021 cacctgggtg gacgatatca ccgtggtgac gcatgtcgcg caagactgta accacgcgtc
    49081 tgttgactgg caggtggtgg ccaatggtga tgtcagcgtt gaactgcgtg atgcggatca
    49141 acaggtggtt gcaactggac aaggcactag cgggactttg caagtggtga atccgcacct
    49201 ctggcaaccg ggtgaaggtt atctctatga actgtgcgtc acagccaaaa gccagacaga
    49261 gtgtgatatc tacccgcttc gcgtcggcat ccggtcagtg gcagtgaagg gcgaacagtt
    49321 cctgattaac cacaaaccgt tctactttac tggctttggt cgtcatgaag atgcggactt
    49381 gcgtggcaaa ggattcgata acgtgctgat ggtgcacgac cacgcattaa tggactggat
    49441 tggggccaac tcctaccgta cctcgcatta cccttacgct gaagagatgc tcgactgggc
    49501 agatgaacat ggcatcgtgg tgattgatga aactgctgct gtcggcttta acctctcttt
    49561 aggcattggt ttcgaagcgg gcaacaagcc gaaagaactg tacagcgaag aggcagtcaa
    49621 cggggaaact cagcaagcgc acttacaggc gattaaagag ctgatagcgc gtgacaaaaa
    49681 ccacccaagc gtggtgatgt ggagtattgc caacgaaccg gatacccgtc cgcaaggtgc
    49741 acgggaatat ttcgcgccac tggcggaagc aacgcgtaaa ctcgacccga cgcgtccgat
    49801 cacctgcgtc aatgtaatgt tctgcgacgc tcacaccgat accatcagcg atctctttga
    49861 tgtgctgtgc ctgaaccgtt attacggatg gtatgtccaa agcggcgatt tggaaacggc
    49921 agagaaggta ctggaaaaag aacttctggc ctggcaggag aaactgcatc agccgattat
    49981 catcaccgaa tacggcgtgg atacgttagc cgggctgcac tcaatgtaca ccgacatgtg
    50041 gagtgaagag tatcagtgtg catggctgga tatgtatcac cgcgtctttg atcgcgtcag
    50101 cgccgtcgtc ggtgaacagg tatggaattt cgccgatttt gcgacctcgc aaggcatatt
    50161 gcgcgttggc ggtaacaaga aagggatctt cactcgcgac cgcaaaccga agtcggcggc
    50221 ttttctgctg caaaaacgct ggactggcat gaacttcggt gaaaaaccgc agcagggagg
    50281 caaacaatga atcaacaact ctcctggcgc accatcgtcg gctacagcct cggtgacgtc
    50341 gccaataact tcgccttcgc aatgggggcg ctcttcctat tgagttacta caccgacgtc
    50401 gctggcgtcg gtgccgctgc ggcgggcacc atgctgttac tggtgcgggt attcgatgcc
    50461 ttcgccgacg tctttgccgg acgagtggtg gacagtgtga atacccgctg gggaaaattc
    50521 cgcccgtttt tactcttcgg tactgcgccg ttaatgatct tcagcgtgct ggtattctgg
    50581 gtgccgaccg actggagcca tggtagcaaa gtggtgtatg catatttgac ctacatgggc
    50641 ctcgggcttt gctacagcct ggtgaatatt ccttatggtt cacttgctac cgcgatgacc
    50701 caacaaccac aatcccgcgc ccgtctgggc gcggctcgcg ggattgccgc ttcattaacc
    50761 tttgtctgcc tggcatttct gataggaccg agcattaaga actccagccc ggaagagatg
    50821 gtgtcggtat accatttctg gacgattgtg ctggcgattg ccggaatggt gctttacttc
    50881 atctgcttca aatcgacgcg tgagaatgtg gtacgtatcg tggcgcagcc gtcattgaag
    50941 atcagtctgc aaaccctgaa acggaatcgc ccgctgttta tgttgtgcat cggtgcgctg
    51001 tgtgtgctga tttcgacctt cgcggttagc gcctcgtcgt tgttctacgt gcgctatgtg
    51061 ttaaatgata ccgggctgtt tactgtgctg gtactggtgc aaaacctggt cggtactgtg
    51121 gcatcggcac cgctggtgcc ggggatggtc gcgaggatcg gtaaaaagaa taccttcctg
    51181 attggcgctt tgctgggaac ctgcggttat ctgctattct tctgggtttc cgtctggtca
    51241 ctgccggtgg cgttggttgc gttggccatc gcttcaattg gtcagggcgt tactatgact
    51301 gtgatgtggg cactggaagc tgataccgta gaatacggtg aatacctgac cggcgtgcga
    51361 attgaagggc tcacctattc actattctca tttacccgta aatgcggtca ggcaatcgga
    51421 ggttcaattc ctgcctttat tttgggatta agcggatata tcgccaatca ggtgcaaacg
    51481 ccggaagtta ttatgggcat ccgcacatca attgccttag taccttgcgg atttatgcta
    51541 ctggcattcg ttattatctg gttttatccg ctcacggata aaaaattcaa agaaatcgtg
    51601 gttgaaattg ataatcgtaa aaaagtgcag cagcaattaa tcagcgatat cactaattaa
    51661 tattcaataa aaataatcag aacatcaaag gtgcaactat gagaaaaata gtggccatgg
    51721 ccgttatttg cctgacggct gcctctggcc ttacctctgc ttatgcggcg caactggctg
    51781 acgatgaagc gggactacgc atcagactga aaaacgaatt gcgcagggct gataagccca
    51841 gtgctggcgc gggaagagat atttacgcat gggtacaggg aggattgctc gatttcaata
    51901 gtggttatta ttccaatatt attggcgttg aaggcggggc gtattatgtt tataaattag
    51961 gtgctcgtgc tgatatgagt acccggtggt atcttgatgg tgataaaagt tttggctttg
    52021 ccctaggggc agtaaaaata aaacccagtg aaaatagcct gcttaaatta ggtcgcttcg
    52081 ggacggatta tagttacggt agcttacctt atcgtattcc gttaatggct ggcagttcgc
    52141 aacgtacatt accgacagtt tctgaaggag cattaggtta ttgggcgtta acgccaaata
    52201 ttgatctgtg gggaatgtgg cgttcacgag tatttttatg gaccgattca acaaccggta
    52261 ttcgtgatga aggggtgtat aacagccaga cgggaaaata cgataaacat cgcgcacgtt
    52321 cttttttagc cgccagttgg catgatgata ccagtcgcta ttctctgggg ggatcggtac
    52381 agaaagatgt ttccaatcag atacaaagta ttctcgagaa aggcataccg ctcgacccga
    52441 attatacgtt gaaaggggag ttgctcggct tttacgcgca actcgaaggt ttaagtcgta
    52501 ataccagcca gcccaatgat acggcgttgg ttagtggaca agtgacctgg aatgcgccgt
    52561 ggggaagcgt atttggcagt ggtggttatt tgcgccatgc aatgaatggt gccgtggtgg
    52621 ataccgacat tggctatccc ttttcattaa gtcttgatcg taaccgtgaa ggaatgcagt
    52681 cctggcaatt gggcgtcaac tatcgtttaa cgccgcaatt tacactgaca tttgcaccga
    52741 ttgtgactcg cggctatgaa tccagtaaac gagatgtgcg gattgaaggc gcgggtatct
    52801 taggtggtat gaactatcgg gtcagcgaag ggccgttaca agggatgaat ttctttcttg
    52861 ctgccgataa agggcgggaa aagcgcgatg gcagtgcgct gggcgatcgc ctgaattact
    52921 gggatgtgaa aatgagtatt cagtatgact ttatgctgaa gtaagaaata acgccggaga
    52981 gaaaaacctc cggcgtttca gattgttgac aaagtgcgcg ttttttatgc cggatgcggc
    53041 gtaaacgcct tatccagcct acaaaaactc ataaattcaa agtgttgcag gtaaaggtag
    53101 gcctgataag cgtagcgcat caggcaatct ctggtttgtt ttcagatgaa aacgccggag
    53161 tgaaaattct ccggcgtttt ggtcgtgaat tactgctgcg gaattgccgg tacagccgga
    53221 acgttaagag ctggcatcgc aaacatgcca acaaaatctt ctaacgacat tttctgccca
    53281 tttaacgtta tctgaccgtt agcatattgc aggctggtgg tgatggtatt gtcctgcaag
    53341 gtggtcagac ggaacatctg ccccattgct gatgcacctt caacttgctg tttcgccagt
    53401 tttttcgctt gatcttcctg ataaccttcc agcttcgcta cctgagtcat aaactcagtt
    53461 gccatatcca ccggaatggt cagtttcgca tccagagatt taaccgagcg gtccacttcc
    53521 tgcgccagcg tttgcggcgc ttctttagtc gttgccggat ctttcaggaa cagcgacaga
    53581 ttcagcgcac tttcaccctg actgtttttc cagcttagcg gtgcgatagt aatcaccgga
    53641 tcgcctttca acatcagcgg cagggcgcta aagaaggctt ccgtcacttt ctcctgataa
    53701 agtgcgggat tgttggcaat ttctggctgt gccagcagcg cctgagtttg cgcgttatat
    53761 tgctggctaa actgatgcca ggcttcacca tcaatctggc cgacttttaa agtcagcttg
    53821 ccgctgccca gatcctgatt ctgtaccttc aggctgttta gcgagtaatc cagttggcta
    53881 ttgatcgttt taccatcatt gaccagatcc gatttaccgc tgatctccat gccttccagc
    53941 agtgccagtt ctttgccttc caccgaaatg gtcatttttt ccagtgacag tttttggttt
    54001 cctacgcgct caccaaaact tgccagcgtg ctggaaccgt cggttttcag attattaaag
    54061 gtcaactgca ctttctggtt gtattcgtta actgcgtcta tccgaccact ttgcgcctcc
    54121 ccggaaaggg agatagcttt gccgtctctg tccgcattta actggaactc gccgccgcta
    54181 aaggcgactt tttcatcctt ttgctcgtaa ttcagtggct tgagcgaaat atcggaactg
    54241 gaatcaccgc tgtaaccaat gcgcgagtta atctcaaaag gcgtttcacc ttttgccata
    54301 tcaaacagtg gtttgcttac ttcgttatta accagcgtgg tttgaattga tgccatcgac
    54361 gggatcaggt tcagtttttt aagctgggca agcgggaagg gaccatgatc aaccgattcg
    54421 ttgaagatga cgctctgacc gcttttaatc cacggatttt ctttcccggc aatgggtttc
    54481 accaacagtt gcaactggct gctgaatacg ccgcgatgat agttttgata actcacttcc
    54541 aggttggatt caggagctgt cagtttgagt tgcgcgttcg cctgcgcgac catgtcttcg
    54601 agatgggttt caatcttctt gcctgtatac catgcgccgc ctgtccagac tacgcctagc
    54661 gcaacaatga cgcctaccgc taccagcgat ttattcataa tgattatcca taaaatgaaa
    54721 tcaggcggac tggccgcctg aaggtgttat aagcctttaa taagcttagc aagagatgtt
    54781 aattttttca gtaagctctt acagcttgtt gtaaacacgc gctaaacggc cgtggccttt
    54841 gacagtcacc ggtgattcgt tggcggcaat aaacgctgat tcacccggtt taagctgtaa
    54901 ctgctgagaa cctttccaca acgttgcatc gccttcgacg cagaacaaaa tggcggcact
    54961 ctgctggcta atggtggttt ctttatcact aaggtcatgc agcgagaagg caaaatcatc
    55021 cactggaatc gggaagtcca gttctgcacc ttgtttcacc ggctgggtca acaactggtt
    55081 agccggtttg gcttcgaatt tcacattggc aaccagttcc ggaatatcaa tgtacttagg
    55141 cgtcagaccc gcacgcagca cgttatcgga gttcgccatc acttccagcg ccacgccttg
    55201 caggtaagcg tgcggtgttt cagcgaacag gaacatcgct tcgccaggat tcaatttcac
    55261 cacattcagt aacagcgggg agaacaggcc gctgtcttcc gggtaaaatt cagaaattaa
    55321 acgaatcgtt tgccacggtt caccctgctg actgtcgagc gccgatttta aaatcgccag
    55381 cgcgcgggat ttttcttcac cctgcatatt caacaggctg gcgaacagtt cgcttaaacg
    55441 ttcggcatta ggctgttgta aaaagtgagc aattgccgga tgtgcacctg cgactggctg
    55501 gagtagggag acaatctcgg aaaactcacg aaacgcgttc atcgcaagga aaggcgtcag
    55561 cgcaaaaacc agctccggct tgtggttagg atctttatag ttacgctcgg cggcatccat
    55621 cgggatacct gcggcatttt ctttggcaaa accgatttca gaattgcgtt tgtttggatg
    55681 aacctgaatg gagagcggct gtgctgcgca taatactttg aacaggaaag gcagttcgcc
    55741 aaagcgtttg gcaacggcct ctccgagcag agtcgattta ttactctcaa tcacatcacg
    55801 cagtgaaacg atatctccgg cggcattctg cacccgtgaa ctgcttttcg gatgtgcgcc
    55861 catccacagc tcggccatcg gctggctgga cggattttcc ataccataaa gttcagtcaa
    55921 cgccgttttg ctgccccagg catagttttg cactgagtta atgagttttt gcatgatcaa
    55981 tccctgtttt aatgtggaaa ttaatcccgc tattaaagca agaatcctac gggaagtaac
    56041 ctggagccgc aaaaagtcgt actagtctca gtttttgtta aaaaagtgtg taggatattg
    56101 ttactcgctt ttaacagggc aacggaacac ccgcccagag cataaccaaa ccaggcagta
    56161 agtgagagaa caatgtcaaa caaacccttt cattatcagg ctccttttcc actcaaaaaa
    56221 gatgatactg agtattacct gctaaccagc gaacacgtta gcgtatctga atttgaaggg
    56281 caggagattt tgaaagtcgc acccgaagcg ttaactctgt tggcgcgtca ggcatttcat
    56341 gatgcgtcat ttatgctgcg tccggctcac caacaacagg tggccgacat tctgcgtgac
    56401 ccggaagcca gcgaaaatga taaatatgtg gcgctgcaat tcctgcgcaa ctccgacatc
    56461 gcggcgaaag gtgttctgcc aacctgtcag gataccggca ctgcgattat tgttggtaaa
    56521 aaagggcagc gtgtatggac cggtggctgt gatgaagcgg cgctggcgcg cggtgtctat
    56581 aacacttata tcgaagataa tttgcgctac tcgcaaaacg cgccgctgga tatgtataaa
    56641 gaggtgaata ccggcaccaa tctgccagcg cagatcgatc tttatgccgt tgatggcgac
    56701 gagtacaaat tcctctgtat cgccaaaggt ggtggttcgg caaacaagac gtatctctat
    56761 caggaaacca aagcgttact aacgccgggg aaactgaaaa attacctggt tgagaagatg
    56821 cgcacgctgg gtacggcggc ctgtcctccg tatcatattg cgttcgtaat tggtggaact
    56881 tctgcagaaa ctaaccttaa aacagtgaaa ctggcttccg ctaaatacta tgacgaactg
    56941 ccaacggaag ggaatgagca cggtcaggca ttccgcgatg tggaactgga aaaagaattg
    57001 ctgatcgaag cgcaaaatct cggtctgggt gcgcagtttg gtggtaaata cttcgctcac
    57061 gacatacgcg tgattcgcct gccacgtcac ggcgcatcct gtccggttgg tatgggtgtt
    57121 tcctgctctg ctgaccgtaa tatcaaagcg aagatcaacc gtcaggggat ctggatcgaa
    57181 aaactggaac ataatccagg taaatatatc cctgaagagc tgcgtaaagc gggagaaggc
    57241 gaagcggtgc gcgttgacct taaccgtccg atgaaagaga tcctcgcaca gttgtcgcag
    57301 tatcccgttt ctacacgctt atcgcttaac ggcacgatta tcgtcggtcg tgatattgct
    57361 cacgccaaac tgaaagagcg gatggataac ggtgaagggc tgccgcagta cattaaagat
    57421 catccgattt actacgcggg tccggccaaa acgccggaag gttatgcctc cggttctctt
    57481 ggcccaacga ccgccggacg gatggattct tatgtcgatc aactgcaagc gcagggcgga
    57541 agtatgatca tgctggcgaa aggcaaccgc agccagcagg tgacggatgc ctgtaaaaaa
    57601 cacggcggct tctaccttgg cagtatcggt ggtccggccg ctgtattggc gcagggaagt
    57661 attaagagcc tggaatgtgt tgaatatccg gaactgggaa tggaagccat ctggaaaatt
    57721 gaagtggaag atttcccggc gtttatcctt gtggatgata aaggaaatga cttcttccag
    57781 cagatacaac tcacacagtg cactcgctgt gtgaaataaa cagagccgcc cttcggggcg
    57841 gtttttttac atggcacgaa aaaccaaaca tttgttatca aatagtaaat aataagtgag
    57901 ctaaaagttg cttaacgaaa gcaaaacaga aagaaaaaat taaacaggtg aggagcaggc
    57961 catgaataca gtacgcagcg aaaaagattc gatgggggcg attgatgtcc cggcagataa
    58021 gctgtggggc gcacaaactc aacgctcgct ggagcatttc cgcatttcga cggagaaaat
    58081 gcccacctca ctgattcatg cgctggcgct aaccaagcgc gcagcggcaa aagttaatga
    58141 agatttaggc ttgttgtctg aagagaaagc gagcgccatt cggcaggcgg cggatgaagt
    58201 actggcagga cagcatgacg acgaattccc gctggctatc tggcagaccg gctccggcac
    58261 gcaaagtaac atgaacatga acgaagtgct ggctaaccgg gccagtgaat tactcggcgg
    58321 cgtgcgcggg atggaacgta aagttcaccc taacgacgac gtgaacaaaa gccaaagttc
    58381 caacgatgtc tttccgacgg cgatgcacgt tgcggcgctg ctggcgctgc gcaagcaact
    58441 cattccgcag cttaaaaccc tgacacagac actgagtgaa aaatcgcgtg catttgccga
    58501 tatcgtcaaa atcggtcgaa cccacttgca ggacgccacg ccgctaacac tagggcagga
    58561 gatttccggc tgggtagcga tgctcgagca taatctcaaa catatcgaat acagcctgcc
    58621 tcacgtagcg gaactggctc ttggcggtac agcggtgggt actggactaa atacccatcc
    58681 ggagtatgcg cgtcgcgtag cagatgaact ggcagtcatt acctgtgcac cgtttgttac
    58741 cgcgccgaac aaatttgaag cgctggcgac ctgtgatgcc ctggttcagg cgcacggcgc
    58801 gttgaaaggg ttggctgtgt cactgatgaa aatcgccaat gatgtccgct ggctggcctc
    58861 tggcccgcgc tgcggaattg gtgaaatctc aatcccggaa aatgagccgg gcagctcaat
    58921 catgccgggg aaagtgaatc caacacagtg tgaggcatta accatgctct gctgtcaggt
    58981 gatggggaac gacgtggcga tcaacatggg gggcgcttcc ggtaactttg aactgaacgt
    59041 cttccgtcca atggtgatcc acaatttcct gcaatcggtg cgcttgctgg cagatggcat
    59101 ggaaagtttt aacaaacact gcgcagtggg tattgaaccg aatcgtgagc gaatcaatca
    59161 attactcaat gaatcgctga tgctggtgac tgcgcttaac acccacattg gttatgacaa
    59221 agccgcggag atcgccaaaa aagcgcataa agaagggctg accttaaaag ctgcggccct
    59281 tgcgctgggg tatcttagcg aagccgagtt tgacagctgg gtacggccag aacagatggt
    59341 cggcagtatg aaagccgggc gttaatctgc aacatacagg tgcagccgtg gaatgatcaa
    59401 acgaagcggc tgcgcctgtg gtttataacg gtgctgcaca ttgtcggcat cgtaatttaa
    59461 caactcacca acgtccggca cgcccgcgcc attatcccga ttaatcagtg caatcagtgg
    59521 tgtagggcag gcgtgttgga cttgtttttg atctcctttg taccagacgc gggcaatcgg
    59581 ctgcaccttc accggacgtt tgatttttaa cttcgcgttc tgtggcaggg cagcgatatc
    59641 ctgatactct cgctccagtt ttctttgcca ctcctcgcgc gtccacggtg cgacactgcg
    59701 tggtgatttc aggctttttt ccagctgtgc caggacttca tcacgatgca aattcttaat
    59761 gatatgttta ttagcccaac caaagcgtaa agtggcgggg tcgtgcagaa cggtgagcgt
    59821 gcggtaagca ttaagggtga tcagccccgg caaatgacga tgcacccatt caaaacgtgc
    59881 cgcggtgggg agttctgatt caaccgtgac gatatgctcg aacgtggtct tgagtttatt
    59941 gatgtgctga atatgactga ccaacgctgc ttgcgaaagg ttatcgacct ggtaacacaa
    60001 cacgccaggc agacggacag cggccttgct gctgcgattt tcggactgtt gttgaataaa
    60061 taaatggcgg aaatgacgca acgccagcga ctgcgcgtcg ttgccgagat gttgttttac
    60121 ctcaatacga ttaagcggat tatgctcatc ctcttttttt acctccggca aagagaacac
    60181 gcgggcaacc aatagcttgt gttgctcaag atgagcggca aatgtagcca gctcttgttc
    60241 catctggcga aaggtagtgt tgagtcggtc tacgagatcg taacgcgcca taatattaac
    60301 cactttagtt acaacatact tattttatag cacagtcgtg gtgacttgac catcgtgcgc
    60361 gtagtgtcag gcagaggtaa attgcgggat gttatgccat aacggccagc taaacgagaa
    60421 gcgagcacca cccagttcgc tggtgtcaca attaaccgta ccgcccattg ccagtgctat
    60481 agagtggaca attgccagcc ccagcccgca gccgccggtt gagcgatccc ggctgggatc
    60541 gaggcgaaca aaaggttcaa agatatgttc gcggttttct ggggcaatcc ctgggccatc
    60601 atcctcaaca attaatgtcg ctctattccc cgacagtagc aggctggttt caaccgttga
    60661 atggcagtac cgcagggcgt tattgagcaa attatccagc acgcgctcca ttaagcgcat
    60721 atccaacgcc gcataatggc cttgcgcgag cgttttaatc cgtaccgttt tatcgggcgt
    60781 tactgcctga atgtctgcca gatgcgttga cagccacaac ggcaggtctg gttcgctaag
    60841 atgaagctcg ttttgtgggc gatcgagtcg ggcataagtc agcagctctt caattaaagc
    60901 ttcaagttga ctgatatcac gattcaacgc ctgggattcg gcggcgctca ggttatcgct
    60961 catctccagt cgataacgca ggcgcactaa cggtgttcgc agttcgtgag cgataccgtc
    61021 aataagctgt tttttgctgg caatcaaggc gttgatattg tccgccatct ggttaaatgc
    61081 gataccaagt cgttcaaagc tcgaaccctc atcaaagtgg atacgctcat tgagatgccc
    61141 atcgccaaat cgttgcgccg ctgcttccag ttttaacata tcctgccagt gcggacgcat
    61201 ccagataaac accggaaagg cgagggaaat agcaataaaa gcgatcaggg cgatatccag
    61261 caatcgcatc tgatggagat aataaagata aggaacagga ccaactgcca gcacgtagtg
    61321 gctgcgcggg atacgctgca aaaacgtgta ctgatcgtcc agggcgacaa tttcgccgcc
    61381 acgcagtcgg tgcatggaaa tatcatcaag atggtattta ctcaatggct cgacacgcag
    61441 atcgaaagag agatttaaat ccatctcttt cagcgtctta ccccagtcgt gtggggggat
    61501 ctcacgcaat tcgctgcgca tcagatacag cgaactgttc atcaaatcat ccagcgactg
    61561 tttgcccgcg cgttcggcgg taaatttgta caccaaccca accagcagag acatcacaag
    61621 gaagcagaca aacaataaca ggtaaaactg gataaacagt tttttcatcg cttattccca
    61681 tgcatgaggc gcaaaaagat agcctttgtt acgcactgtt ttaatgcgat aaggttctgc
    61741 ggcgttatcg agcagttttt ttcttaaccg cgaaatagcc acgtccacgc tacgatccag
    61801 tccgtcataa ctgacgccgc gtaaattttt cagcaatgca tcgcggtcca tgatttgccc
    61861 ggcatgggta gctaattccc acaataattc gaaatcagct gtcgagagcg agatttcagt
    61921 gttagccagg gtgactacgc ggttgatggg atcgatggtc aacgtgccga aattcagggc
    61981 tttgtaggga gtcagagacg tttcctgaag acctttgctc agtgtggctt gctcattctg
    62041 acgcaaatgc aaacgtaaac gcgctagcaa aacagcaggg ggcgtcgttt tgagaatata
    62101 gtcgcaggca cccatttcca gtgccaggat gtggttcata tcgctatcga gagaggttag
    62161 aagaacaatc ggtccagacc actttgcgcg taaatcacga caaatggtca tgccgtcctt
    62221 gcctggtagc atgatgtcga gtaacaccaa atccggattt tctcgcaaaa tggtttcttc
    62281 ggcctggtcg ccgcgcggct ctacggtaac ctgcatatca tgttttgcca ggtacgcggc
    62341 aatcagtgaa ccgacttccg catcatcttc cacaaatacg atagtgttca taacattcac
    62401 ggtagatata aaaacgtcac aatacaccgc gctgttttta cttactatca atcgtttcta
    62461 aacaagtttt catcaggtat tctactgatg acttgttatg gaagtgttaa ggtaaaaaaa
    62521 tggggctggt aatcaaagcc gcgctcggtg cgctggtagt gctgttgatt ggtgttttag
    62581 caaaaacgaa aaattattat atcgccgggc tgattccact tttcccgacc tttgcgctta
    62641 tcgcgcatta tattgttgcc agcgaacgcg gcattgaagc cttacgcgca accatcattt
    62701 ttagtatgtg gtcgattatt ccctattttg tttacctggt gtcgctgtgg tatttcaccg
    62761 gaatgatgcg cttgcccgcc gcttttgttg gttctgttgc gtgttggggg ataagcgcat
    62821 gggtgttgat tatatgctgg ataaagctgc attaacgcag atgacgaccg ccatcaagtg
    62881 ggaaactgcg tccggtgaca aaacaactgg taagtaagta atcgaccagg tcgatcactt
    62941 ctttctcgcc aggagcggtt ttcatcagtg atttattcag cgcctgttgt cgatattcgg
    63001 catcatcatg ttcattaaac aggatcagcg atggcgcaat agaattcact ttcacttccg
    63061 gtgccagctt gcgggcaaac gagcgggtca tattatccag tgccgctttg cttgcagcat
    63121 acgcaatatg tttgtcgcta ccgcgctcca ccacataatc ggtaaagtga atgatatcgc
    63181 tggcggcgtg tccgtgccca cgcagtaatc tttccagcgc atggttgagc aggtatgggg
    63241 tattaacgtg gatctgcatc atgcaagcca gtacgtcggc cagtggcgca cccggttttt
    63301 ccgccatcca cgcactggcg ttatgcaaaa tagcacgcag accatgggtg ctttttagta
    63361 cttcatcggc aaacgccatc acaccgtcgt tggtcgaaaa atcagcctga atacactgcg
    63421 cacctgcatt aatcagtcca tcaatggctg gatagtgtgt ccgatagctg acaatcaccg
    63481 gttgcttttg attaatgaaa tgccatgcga gggcgaggcc gatgcgacga cctccgccag
    63541 taattaatat tggcaagggc tgggctttac ccatcgttat ctcctttgct atccaacgat
    63601 gggatgaacg ttatcccacc agcatccagg tcgccggaac tgaggcaatt aacagcatgc
    63661 caatcagcac catttcctga cggttcagta cattatcatg tgtatgcgtt ttgcgcgcat
    63721 acaggaaaac cagcagcccc ggcgcataca gaacaacgga taacagcaag tgcattggac
    63781 cagaggcata caataaccat aagccataaa tgcaggcacc gacacctacc gctttatgca
    63841 gtggacgggt tgcgattttc agcaagaacg cgccgaccag gaaatagggc accagaatca
    63901 tttctgaggc gatggtcagc aacgtgttgt aatcggaacc ggtcagccag atgagtacca
    63961 gacaaatttg cacgcagatg ttggtcaacc acagcgaggc ggatggcgca gcttgtgcgt
    64021 tctggcgcgc aaaaatgcgt gggaatgctt tatgagtggc agccaggaac ggaacttctg
    64081 ccgccatgat ggtccagctt aagtacgcgc cgcaaacgga aacgatcaaa ccggcagcga
    64141 tgatgatttc gccccatggt cccatcattt ccaccatcag accggccatt gacgggttac
    64201 gaatttcagc cagttcagga cgtgccacca cgcccagcga aagcagcgtt accagcaagt
    64261 aaacgcccag agcggagaga accgccagca gtgtcgcttt gccaacatca cgtttattac
    64321 gcgcacgcgc agaaacaacc acggcacctt ccacaccaat gaaaacccac agggtgatca
    64381 gcatggtgtt tttcacctgt tcccacacgg gtacgccaag tgcaagtccg gtgaagtcga
    64441 gcttgaaggt atccagtttg aacatcatca tcgccagcac aacaaacaga cccagcggca
    64501 acaattttgc cagtgtcgcc accaggttaa tgctggcagc ggtttgcacc ccgcgcagga
    64561 tcaaaaagtg aacaatccac aataaagccg atgcaccgac tatcgattgc caggtattac
    64621 catcgccgaa caggcgcaat tccggcgtgt ccgtaaaaaa gcttaacgcg gaaaaaacga
    64681 tcaccagata ggagacgttg gcgatgactg cgcacagcca gtatccccat gcggaacaaa
    64741 agccgattag ctcgccaaac ccttcgcggg cataggtaaa gataccgccg tcaagttcgg
    64801 gacgaatgcg cgtgaggatc agcatggcaa aggccagcaa taaaatgcca gcgccagtaa
    64861 taccccagcc gatgagcagt gctgccgggc tggcaactgc cgccatattt tgcggcagac
    64921 tgaaaacacc cgcgcccagc attgagctta ataccagcgc ggtgagtgcg ctcagtccca
    64981 gtttcttttc catcgatatc cagtgattaa aacgtgataa gaagaataaa tattagggca
    65041 aaacgcataa aaatggagtt tgccactgaa gcgcgggatt ttacgaagag atgtgtctgc
    65101 atgcaatggt cgcggggaaa tttgtgacta aaaatgcgaa aggcggcatc aagccgcctt
    65161 ataggagtaa ctgaatagtt atttatacag atctgcgctg acggtcaggt tattaccacg
    65221 ttcctgccac tggcgggtga tgtggtaata cttagcacct ttcttcgcgg cacgtttcgc
    65281 aacctgatag gagacttcgg tcatgttgcc gtagttgcca gagaatttga tgctgtcgaa
    65341 cgggaccatc atcgctgctg tcgctttgtt cagttcttcg actttagtgc cgtcaggaag
    65401 cgtgacagtg taacgtccgc cttttgatga ctgggtttca aagaaacgac cgacttcaga
    65461 acttggtgat gcggtagtcg caacacctgg gatctcaact ttcttcgcgg cttcgccacc
    65521 ggcagccaga gctgcacgtc ctgcttcgga atctgccggg atcacatccg ggctctggac
    65581 gatacgtttc ttagcatctt ttttatagat gaatgcagta atacgctggt tgccgccctg
    65641 gttggcatcg atttgacgaa caatgtagaa agagtaggca cctttcgctt ttgctgcttt
    65701 ggtgatggca tcattgactt ctggctggct acgatagaag ccctggacgg tgaccgtgtc
    65761 aaacggttca atcagaacag cctgatcttt cggcagttcg acaacaccgt taattacgcg
    65821 attacttgtt tcttctgctt tttcagcatc ggctttatag aggtcagcga ccacacgcca
    65881 gttaccgctg ttaccaaaat cagaagtgtc gacaacataa aaagaggcgg caccttcttt
    65941 atctgcgcga cgagaaacgg ctttcaccgc ttcgccaata gcattaaaac gaccggtaac
    66001 cactacacgg tcaaaaggtt taaccgctgc cgcttgctcc ggtgtcagtt ctgttgctgc
    66061 gttaacggag aatgccgtag cagaaagcag tgccgacgcc aggagggtgt tcttaagctt
    66121 cataaaaata atccttcgcc ttgcgcaaac caggtactgg tattgttatt aacgagaaac
    66181 gtggctgatt attgcattta aacggtgtaa ctgtctgcgt catttttcat atcacattcc
    66241 ttaagccaat tttaatcctg ctcaaatgac cgtctatgct taaaaaacag ccgtatcagc
    66301 atcattacta ctgaagcaac tgaattgtat aagttaattt aatgttaagt agtgattcgt
    66361 gccggggcga tgtctcgttt tacccgaccg tcgaagacaa ttatcagtct ttatccggcg
    66421 ttctaaggtg tttatcccac tatcacggct gaatcgttaa tattttgcga gttcacgccg
    66481 aaatactgat ttttggcgct agatcacagg cataattttc agtacgttat agggcgtttg
    66541 ttactaattt attttaacgg agtaacattt agctcgtaca tgagcggctt gtgtggctcc
    66601 tgacacaggc aaaccatcat caataaaacc gatggaaggg aatatcatgc gaattggcat
    66661 accaagagaa cggttaacca atgaaacccg tgttgcagca acgccaaaaa cagtggaaca
    66721 gctgctgaaa ctgggtttta ccgtcgcggt agagagcggc gcgggtcaac tggcaagttt
    66781 tgacgataaa gcgtttgtgc aagcgggcgc tgaaattgta gaagggaata gcgtctggca
    66841 gtcagagatc attctgaagg tcaatgcgcc gttagatgat gaaattgcgt tactgaatcc
    66901 tgggacaacg ctggtgagtt ttatctggcc tgcgcagaat ccggaattaa tgcaaaaact
    66961 tgcggaacgt aacgtgaccg tgatggcgat ggattctgtg ccgcgtatct cacgcgcaca
    67021 atcgctggac gcactaagct cgatggcgaa catcgccggt tatcgcgcca ttgttgaagc
    67081 ggcacatgaa tttgggcgct tctttaccgg gcaaattact gcggccggga aagtgccacc
    67141 ggcaaaagtg atggtgattg gtgcgggtgt tgcaggtctg gccgccattg gcgcagcaaa
    67201 cagtctcggc gcgattgtgc gtgcattcga cacccgcccg gaagtgaaag aacaagttca
    67261 aagtatgggc gcggaattcc tcgagctgga ttttaaagag gaagcgggca gcggcgatgg
    67321 ctatgccaaa gtgatgtcgg acgcgttcat caaagcggaa atggaactct ttgccgccca
    67381 ggcaaaagag gtcgatatca ttgtcaccac cgcgcttatt ccaggcaaac cagcgccgaa
    67441 gctaattacc cgtgaaatgg ttgactccat gaaggcgggc agtgtgattg tcgacctggc
    67501 agcccaaaac ggtggcaact gtgaatacac cgtgccgggt gaaatcttca ctacggaaaa
    67561 tggtgtcaaa gtgattggtt ataccgatct tccgggccgt ctgccgacgc aatcctcaca
    67621 gctttacggt actaacctcg ttaatctgct gaaactgttg tgcaaagaga aagacggcaa
    67681 tatcactgtt gattttgatg atgtggtgat tcgcggcgtg accgtgatcc gtgcgggcga
    67741 aattacctgg ccggcaccgc cgattcaggt atcagctcag ccgcaggcgg cacaaaaagc
    67801 ggcaccggaa gtgaaaactg aggaaaaatg tgcctgctca ccgtggcgta aatacgcatt
    67861 gatggcgctg gcaatcatcc ttttcggttg gctggcaagc gttgcgccga aagagtttct
    67921 tgggcacttc accgttttcg cgctggcctg cgttgtcggt tattacgtgg tgtggaatgt
    67981 atcgcatgcg ctgcatacac cgttgatgtc ggtcaccaac gcgatttcag ggattattgt
    68041 tgtcggagca ctgttgcaga ttggccaggg cggctgggtt agcttcctta gttttatcgc
    68101 ggtgcttata gccagtatta atattttcgg tggcttcacc gtgactcagc gcatgctgaa
    68161 aatgttccgc aaaaattaag gggtaacata tgtctggagg attagttaca gctgcataca
    68221 ttgttgccgc gatcctgttt atcttcagtc tggccggtct ttcgaaacat gaaacgtctc
    68281 gccagggtaa caacttcggt atcgccggga tggcgattgc gttaatcgca accatttttg
    68341 gaccggatac gggtaatgtt ggctggatct tgctggcgat ggtcattggt ggggcaattg
    68401 gtatccgtct ggcgaagaaa gttgaaatga ccgaaatgcc agaactggtg gcgatcctgc
    68461 acagcttcgt gggtctggcg gcagtgctgg ttggctttaa cagctatctg catcatgacg
    68521 cgggaatggc accgattctg gtcaatattc acctgacgga agtgttcctc ggtatcttca
    68581 tcggggcggt aacgttcacg ggttcggtgg tggcgttcgg caaactgtgt ggcaagattt
    68641 cgtctaaacc gttgatgctg ccaaaccgtc acaaaatgaa cctggcggct ctggtcgttt
    68701 ccttcctgct gctgattgta tttgttcgca cggacagcgt cggcctgcaa gtgctggcat
    68761 tgctaataat gaccgccatt gcgctggtat tcggctggca tttagtcgcc tccatcggtg
    68821 gtgcagatat gccagtggtg gtgtcgatgc tgaactcgta ctccggctgg gcggctgcgg
    68881 ctgcgggctt tatgctcagc aacgacctgc tgattgtgac cggtgcgctg gtcggttctt
    68941 cgggggctat cctttcttac attatgtgta aggcgatgaa ccgttccttt atcagcgtta
    69001 ttgcgggtgg tttcggcacc gacggctctt ctactggcga tgatcaggaa gtgggcgagc
    69061 accgcgaaat caccgcagaa gagacagcgg aactgctgaa aaactcccat tcagtgatca
    69121 ttactccggg gtacggcatg gcagtcgcgc aggcgcaata tcctgtcgct gaaattaccg
    69181 agaaactgcg cgctcgtggt atcaacgtgc gtttcggtat ccacccggtt gcggggcgtt
    69241 tgcctggaca tatgaacgta ttgctggctg aagcaaaagt accgtatgac atcgtgctgg
    69301 aaatggacga gatcaacgat gactttgctg ataccgatac cgtactggtg attggtgcta
    69361 acgatacggt taacccggcg gcgcaggatg atccgaagag tcctattgct ggtatgcctg
    69421 ttctggaagt gtggaaagcg cagaacgtga ttgtctttaa acgttcgatg aacactggct
    69481 atgctggtgt gcaaaacccg ctgttcttca aggaaaacac ccacatgctg tttggtgacg
    69541 ccaaagccag cgtggatgca atcctgaaag ctctgtaacc ctgacggcct ctgcggaggc
    69601 cgtcactctt tattgagatc gcttaacaga acgtcgatgc tttgacctcc cgctgtttgt
    69661 tcaagcgcaa ttttgacaat aattgttaac ggcacggaaa gcagcatacc caccggtcct
    69721 aacaaccatc cccaaaaaat caacgacaaa aataccacca atgtggaaag ccccagccca
    69781 cgtcccatga tgcgcggctc cagaatattg ccgaagacca gattaatcag cagatatccc
    69841 gccagcacca gcaacgcttc gtagaagcca ttaaacacca gtacctgagc gatagggggg
    69901 attgccgcga gaactgaacc aatattaggg atgtaattaa gcgcaaaggc cagcaatccc
    69961 cagacaaaag cgaagcgaac atcgagtgcg gcgagcatcg cccaggcgac caggccggtg
    70021 atgatgctga tggctgtttt cagcaccaga taatgagaaa cactgtcaat tgcacgttga
    70081 atcgccgcca tcccttcaac cggacgcgcc atcatttgct gaaattttcc gggcaattgt
    70141 ggcacttcga gcagcataaa cagcaccgtc agcagcaata aaaatattga tgacatggca
    70201 ttagataact gcgtcaataa gttggtgagc aacgtcatcg ccgcgttcgg atcaatgtaa
    70261 tgcgccagct ggtcaactga gacgtcaatc cctacgcgtt gcaacaacgg ctcaagagct
    70321 tgcagcggcg tcataataga gttgcgatat tgcggtaacg tccgcgtcaa ctcgttgagc
    70381 gcggaaccca gataagctaa tagcaacacc atcgccatca cgatgatggt catcaaaatc
    70441 gacaccgcca gtacacgcgg cactcgccag cggaccatgt gttgcaccag cgggttaaga
    70501 ataacagcaa taaataatgc gagaataaac ggcacgatga tctcggcggc aaaacggata
    70561 ccgcagagaa taatgaccag cattcccaac ataatgacga tttttaggcc attgagcgtg
    70621 atgatcggct ttgccatgct tgtccccggt ttttcttcct ttgctaataa taatgtcttt
    70681 ttcgctccgt catcataacg aaaatcaaac cgctcaggta aagaagtgaa aatattttga
    70741 gttaattctt aagctatgat acaaatcagg cgtgttcaac taccgaggac aattatcatc
    70801 cgcgatgacg agaagcaaca ctgcggataa ttgtaatatt atggacaatt tgttcaggac
    70861 gttattttct acatttaccc atcttcgtac ctcatccact atcttgctcg taggtgagca
    70921 gcactggcgc aacgcgcttt agtcctttct tctgcctaag cttgccctat gcgcggggct
    70981 tgaccacttt actttggttt cgctgaatta agcgaaaatt aaaataattc tcttgcagga
    71041 gaaggacaat gtatatttat tggattttat taggtctggc tattgctaca gaaattaccg
    71101 gtacgctgtc aatgaaatgg gcgagcgtca gtgagggaaa tggcggcttt attttaatgc
    71161 tggtgatgat ttctctgtcg tatatatttc tctctttcgc cgttaaaaaa atcgccttag
    71221 gcgtagctta tgcgttgtgg gaaggtatcg gtattttatt tattaccttg ttcagcgttt
    71281 tgttattcga cgaaagttta tcgctgatga aaattgccgg gttaaccacc ctggtcgccg
    71341 ggattgtgtt gataaaatca ggtacccgta aagcgcgtaa acctgaactg gaggtgaacc
    71401 atggcgcagt ttgaatgggt tcacgccgcc tggctggcat tggcaatcgt gctggaaatc
    71461 gttgctaacg tctttttgaa attttctgac ggctttcgtc gcaaaatatt tggcttgctc
    71521 tccctggcgg cggtgctggc tgcctttagt gcgctttctc aggccgtaaa agggatcgac
    71581 ttgtctgtcg cttatgcatt gtggggcggg tttggtattg ccgccacgtt agccgcaggt
    71641 tggatcttgt ttggtcaacg gttaaatcgt aaaggctgga ttggcctggt cttgctgttg
    71701 gctggaatga tcatggtgaa acttgcctga tgaagacgct gcccgcgctg tcgggcagcg
    71761 tttgaacatt atttttgcga cagttgatcc agcttgtcgc gaaaaccggt aacagaaatg
    71821 gcccggttat cggcgcgcca gcgatctttc gcggcaggag ccgaactttg caccccaatt
    71881 aattgccagc cgtcatcggt atgcaacatc agaggcgaac cgctgtcacc cggcaaggta
    71941 tcgcactgat gtgacatcac cgacgtttgc gcccagccag tcacttcaca gttttgatga
    72001 ctgtataacg tatcgagatg atcttcagga tatcccgcct gagtcacttt acgaccagcc
    72061 gattttaatg cggcagtaag cgcggcttta tctccctcaa ataacggcaa cggtgtaatg
    72121 ccagaagggg gattacgcag cacaatcaag ccgaagtccc atggtgcagc tgcgggagga
    72181 acaatccaac catccccatc tgcttttaac cgctttccca gtgtcggatc aacgcggcct
    72241 tctatgtcgt ggatctcata gcgccaaaga cctttatttg acacaaaacg cagcgccact
    72301 gctttatcgg ctttaccctt tggaggtgtc aataaacagt gtcctgccgt taatgccaga
    72361 ttgggtgcaa tcagcgtcgc cgtacataaa ttgccgctgg ccgtttccag ttgcccaacc
    72421 gcatcccacg gtgattgggt cgtgtcattc actggcacac gatcatcatg accaaaaaac
    72481 agggtgctga cctcatcgtt tgccgatttg gcaacgtctg gtttatctgc aaacacaaaa
    72541 gcagacgtca aactaattgc acccaacact acagcaatgg ttgtacgcat atcacactct
    72601 ggtgggtaat tatgattatt aaaagcaaac cctcataaat actatagacg ggacgggatg
    72661 aaagtgggag taaaatcaga taactacagt caggaaagat aaaaacgggc ggcaatcagt
    72721 gcgcataaaa taaggatgat aagaatgaac tcaaagcgat aacggcccac catactaccc
    72781 tccgctaaag gcggtgctaa acgttacccg cttagcaccg taattttcag gcgcgagggg
    72841 gcgcgccagc attactgttg aaaacttacg ctgcgggttg tgcagcaggt tttgccggtt
    72901 gctgatggct gtgtttcccg gcgtgtttct tcgctgcctg cgctttttgt tcaggggctt
    72961 tctgttcagc tttcgtattt ttatgatgct ttttagccgc ctgcgctttc tgggcaggtg
    73021 ctgctttatg ctgtttttta tgatgtgtcg ttttcgccgg cgctgctttg gtggtcgtcg
    73081 cagtcggagc aggtgtggtc gcagtctctg cagcaaaggc ggcagaagac agacccatag
    73141 cagcggcaac aaccagagct aatacttttt tcattgtcat accctcaatt tgttttttca
    73201 tttaacccca ctgcggggcc gttgaaataa ctatatccct gggaatggca gacttccgtg
    73261 agtggttggt ttcagcgtgt aacgatatgt acaaacgctg aataaattac agcgttgata
    73321 ataacgtatt gtgacttaag ggaaatttag ctaccaataa tagtagtctt gatcgggtta
    73381 actattttac tacttacaaa gcggtagaat aactgcgcat cagtaataaa tgacacacag
    73441 caaaatgaat ccgtttattt gggtacttat aatcctgatg acgctagacg cgctgcggga
    73501 attggctggc gcttcgtcta ttttaggatg gctattaacg ttggtttgag caagcaataa
    73561 gtccggacgt gtagttaccg cagtccgggc ttatttttca ggcgtgcaga cgacgatgca
    73621 aacgcgtccc gaccagcaga gcaatgacca gcatcagagc aataaatgcg ccgacgccgt
    73681 tccagccata gttatgccag aaaacaccac ccagcgtccc ggcaatactc gaccccagat
    73741 agtaactgaa cagatacagc gaggaggcct ggcctttagc gcgttttgcg cgggggccaa
    73801 tccagctgct ggcaactgag tgggctgcga agaatcctgc tgagaagagt aacattccgg
    73861 caaagatcag ccacagcgag ctgaataagg tcatcagtaa accaaacagc ataacccccg
    73921 tcgaaaacaa catcaccgga ccgcgcccgt agcgggtggt catggttccg gctttgggtg
    73981 agctccatgt accggtcaaa taagccagcg ataataagcc aaccacggcc tgactgacat
    74041 gccaggggga aagcatcaac cgatagccga tgtaattaaa cagcgtgacg aacgacccca
    74101 tcagcaaaaa gccttctgcg aacaataacg gtaatccccg gtcacgccag tgcagacgaa
    74161 agttgataaa caacgtctta ggtcgcagcg aagtcgggcg aaaatggcgt gattcaggga
    74221 ggattttcca gaacatcaac gccgaggcta gcgcgaaaca accgattgcc gccagagcaa
    74281 ttcgccagtt gaaaaagtcc gtgaagacac cactaattaa gcgcccgctc atgccgccaa
    74341 ttgagttgcc gctgatatac aaccccatcg aaaaggccac gaaactgggg tggatttcct
    74401 cgctaagata agtcatgcca acagctgcca cgccacttaa cgaaagccca atcaaggcgc
    74461 gcataatcaa aatgccgtgc cagctggtca tcattgtcga aagtaacgta caaatggagg
    74521 ccaacagtag cgccgtgacc atcactggtt tgcgaccaat ggcatcggat agggggccag
    74581 taaacagcaa accaatagcc aacatcgccg tggaaatgga cagtgaaata ctactgttcg
    74641 cgggcgttaa gccaaactcc tgcgaaagca ccggaaggat aggctgcaca caatagagaa
    74701 gtgcaaatgt tgccagtccg gcagagaaca gcgccagggt gacgcgcata aattgcggcg
    74761 taccgcgttt aataaattga tttggctgag aaatgctttg cttgtcagtg tcgcttgccg
    74821 gagcgccatc aacagttgta gtacggctca cttgaaatcc ttgctaaata tgcctgtgga
    74881 tcaggcttat acataggtta ggaaaatcga attgttctgt ctaatatatt aataatctca
    74941 aataagatgt tttaaatatg aatattgaac ttcgtcatct gcgttacttt gttgctgttg
    75001 cggaagagct gcatttcggg cgcgccgctg cccgcctgaa tatttcgcaa ccaccgctaa
    75061 gtcagcagat tcaggcactg gagcaacaaa ttggtgcccg actgctggca cgaactaatc
    75121 gcagtgtatt gctgacggca gcaggaaaac agtttcttgc agatagtcgg caaatcctgt
    75181 ctatggtaga tgacgctgcc gctcgcgctg aaagactgca tcagggggaa gcgggggagt
    75241 tgcgcattgg ttttacttcg tccgctcctt ttattcgggc ggtgtccgat acgttatcgc
    75301 tgtttcgccg tgattatccc gatgtccatt tacaaacccg cgaaatgaac actcgtgagc
    75361 aaatcgctcc gctcattgaa ggaacgctgg atatgggatt gctgcgtaac acagcgttac
    75421 cggagacgct tgaacacgca gtcatcgtcc atgaaccgct tatggcgatg atcccgcacg
    75481 atcatcccct ggcaaataac ccgaatgtaa cgctggctga actggcgaaa gaacccttcg
    75541 tcttttttga tccgcacgtc gggacagggc tgtatgacga tattctcggg ctgatgcgac
    75601 gttaccattt gacgcccgtc atcactcagg aggtgggcga ggcaatgacc atcatcggtc
    75661 tggtttccgc cggtctgggt gtttcaattt tgcctgcgtc atttaaacgt gttcagctca
    75721 acgaaatgcg ctgggtgccg attgcagaag aggatgcggt ttctgaaatg tggttggtct
    75781 ggccgaaaca tcatgaacaa agtccagctg cgcgaaactt tcgtattcat ctgctgaatg
    75841 ctctcaggtg agggaaattt cagcgaaaaa gcccgaaaaa tgtgctgtta atcacatgcc
    75901 taagtaaaaa tttgacgaca cgtattgaag tgcttcacca tagcctacag attatttcgg
    75961 agcgcgaaaa tatagggagt atgcggtggt tgctgaaaac cagcctgggc acattgatca
    76021 aataaagcag accaacgcgg gcgcggttta tcgcctgatt gatcagcttg gtccagtctc
    76081 gcgtatcgat ctttcccgtc tggcgcagct ggctcctgcc agtatcacta aaattgtccg
    76141 tgagatgctc gaagcacacc tggtgcaaga gctggaaatc aaagaagcgg ggaaccgtgg
    76201 ccgtccggcg gtggggctgg tggttgaaac tgaagcctgg cactatcttt ctctgcgcat
    76261 tagtcgcggg gagattttcc ttgctctgcg cgatctgagc agcaaactgg tggtggaaga
    76321 gtcgcaggaa ctggcgttaa aagatgactc gccattgctg gatcgtatca tttcccatat
    76381 cgatcagttt tttatccgcc accagaaaaa acttgagcgt ctaacttcga ttgccataac
    76441 cctgccggga attattgata cggaaaatgg cattgtacat cgcatgccgt tctacgagga
    76501 tgtaaaagag atgccgctcg gcgaggctct ggagcagcat accggcgttc cggtttatat
    76561 tcagcatgat atcagcgcat ggacgatggc agaggccttg tttggtgcct cacgcggggc
    76621 gcgcgatgtg attcaggtgg ttatcgatca caacgtgggg gcgggcgtca ttaccgatgg
    76681 tcatctgcta cacgcaggca gcagtagtct cgtggaaata ggccacacac aggtcgaccc
    76741 gtatgggaaa cgctgttatt gcgggaatca cggctgcctc gaaaccatcg ccagtgtgga
    76801 cagtattctt gagctggcac agctgcgtct taatcaatcc atgagctcga tgttacatgg
    76861 acaaccgtta accgtggact cattgtgtca ggcggcattg cgcggcgatc tgctggcaaa
    76921 agacatcatt accggggtgg gcgcgcatgt agggcgcatt cttgccatca tggtgaattt
    76981 atttaaccca caaaaaatac tgattggctc accgttaagt aaagcggcag atatcctctt
    77041 cccggtcatc tcagacagca tccgtcagca ggcccttcct gcgtatagtc agcacatcag
    77101 cgttgagagt actcagtttt ctaaccaggg cacgatggca ggcgctgcac tggtaaaaga
    77161 cgcgatgtat aacggttctt tgttgattcg tctgttgcag ggttaacatt ttttaactgt
    77221 tctaccaaaa tttgcgctat ctcaatttgg gccaggaaag cataacttag actttcaagg
    77281 ttaattattt tcctggttta tatttgtgaa gcataacggt ggagttagtg atgctgaagc
    77341 gtttctttat taccggtaca gacacttctg tagggaaaac ggtggtttcc cgcgcattgc
    77401 tacaagcgtt agcctcccag ggaaaaacgg ttgcgggata taaacccgta gcgaagggga
    77461 gcaaagagac acccgaaggg ctgcgtaata aagatgccct ggtgttgcag agtgtttcaa
    77521 ccatcgaact gccttatgaa gcagttaatc ctatcgcgtt aagcgaagaa gaaagtagcg
    77581 tggcgcacag ttgcccaatc aattacaccc tcatttcaaa cggcctggca aacctgaccg
    77641 ataaagtcga tcatgtcgtg gtagaaggga ctggcggctg gcgcagtctg atgaatgatt
    77701 tgcgtccact ctctgaatgg gtggtgcagg aacaactgcc ggtgttgatg gttgtcggta
    77761 ttcaggaagg ttgcattaac catgcactgc taacagctca ggcgattgcc aacgacgggc
    77821 tgccgctcat tggctgggtg gctaaccgaa tcaacccagg actggcgcat tatgcggaaa
    77881 tcattgatgt gctgggtaaa aaacttccgg caccgctcat tggtgaactg ccttatctgc
    77941 cgcgcgccga acagcgagaa ctggggcaat acatccgctt agctatgctg cgcagtgtgc
    78001 tggcggtaga tagagtcacg gtgtaacgtc cgcgaaatta ccgacgcaat gacgcaggca
    78061 atcaataaac cggggagtag ctgatactcc ccggtcattt cacatatcat caacgtcgac
    78121 ataatcggcg cgtgcgtggt tgccgccaac agtgtcgcca tcccggtcaa tccgagtaaa
    78181 agcgtaattt cttcgccatc agggaaccat aatcccaggc tacgaccata caacatgcca
    78241 atggcaagac cgataaatag cgtcggtgta aagaccccac cgggtgcgcc ggaaccgcta
    78301 ctcgccagca cggcacacag tttacaaagg aagatcccgg caatgatcat taacagtggt
    78361 ggggcggtta aaaaggattg tacggtgcta tagccgttgc cccacactgc aggtgtgaac
    78421 agggaaagca gacccacgat caacccgcct agtgccagtt gccagggcgg cgcaagtttg
    78481 agactcacaa atccacgatg gcaggcgttc attaacgtta acaacagtgg tccgcacaga
    78541 cctgccagca cacctgtact gataatcagc gcatagtcac gagcctgaac cgtcactgag
    78601 agttgtacgt tgtagagtaa cgcgtcgcta tgattaatca gattgctaac cagcaatgcc
    78661 acgacggcgg aaataatcac cgggccgaga gaggccaaca tcatagtgcc aaacagcact
    78721 tcggcgataa ataaactgcc agcaagcggg gcacgatagg ccgcagccat tcccgccgcg
    78781 gccccacagg cgatccataa tttccactcc tggcgtggcg taaaacgttg ggcaaaacag
    78841 gaggcggcaa gggcagctaa aagaatcatc gcaccttcgc gaccaattgc actgccgctg
    78901 gttactacca gcagcgaggc aagcgattta accaggcttg ctgcgtaatc gaactgtcca
    78961 tcggtttgca acgcttccat gtaatcggtc ggcgcatgag ggcgttgttg ggtaaatttc
    79021 tgccagccca tcagcaacaa acccgccgcc agtccgccga gcgccggagt tagcaaccgt
    79081 cgccaggggg aaaggtttgt cgctgcattg accagactgc cggagtcatt attgaggaac
    79141 aaccactcca gtagcagcat cgcatgacga aacccggcaa cggcaaaggc cgcgagaata
    79201 ccgacgactg ttgcgataag cagacggcgg aacatagtgc gcagatccgg atagatgtgt
    79261 agatgatgca tgagcagaaa tgggcaatga aacacgggcg actattttgc ggcaaaagag
    79321 gccagccgca aaagcagtgc gtgctttaag agataaaaaa acgtgacact gtaacctatt
    79381 attgccggat tgcgcgtaat cgtcaccatc cggcaatatt acggtgatcc tatcgaaaca
    79441 gcggtttaac cgcgacagga attaacagtt gtgattgcca ttgcgccagc gttaagcgag
    79501 ccagttcacc cagtgcacgg tagaaagggt gttctgcttt ttcgataaaa acatcaagaa
    79561 aacgtgttga ccacggaaaa aggtgccatg ccagcaattc ttcgcattct gtctggcgac
    79621 cattttccgc caaccacgca gccatcaaca gcagtgaacc aaaatgatct tccggttcgt
    79681 tttgcttcat ttcaaactga atgcctttct cgcgcatcca ctgacgaagt gccaatgttg
    79741 aatcgccaaa cagcacagat tcgcgatcca gccagaccga cccccacggc ggagacggca
    79801 gtgcccacgg gccgacaaac aaacgctgcc aggcctgggc gtgagtctct tcacactgtg
    79861 tctgaaaagc cgtcaccagc ggcgctaatg acgcttctgg tagaggccac tgagtttccc
    79921 agccgtcact ggtgagtacc gcaaccagag gtgcggcttc cgcactctct ggagcgtaat
    79981 aaaacagcgc gcccaacacg cgcgccgcga cagaaaaatt atcttgctgt gaaaaatggg
    80041 tcattcctaa catcctgaaa tgtgcgggtt gccccgcacc aatttgttaa cctgcaatag
    80101 ccattcctac tgtcatgtgc aggccataaa agagcacacg cccgatcatc tcaccgccaa
    80161 gtatgaggat tagccccaga ataagtccgg caacgtgagg ttcacggcga cgaatgagcg
    80221 ggcaaagcca gcatccaaga cctgcgcata acaataccac acgccagacc tgtaaggagg
    80281 cgtaatctgg taccagtgcg ctggcttgtt gcacggatga gtgaatagac gccagagaca
    80341 aaccttgcag cacaatcacc ccggcacaag cgatcagcgc caaaacgcta atgatggcaa
    80401 atggtgtggt attaaatgta acgcgagctg cccgcagaat tgcggcagca agtattggac
    80461 cgctcaacaa taccgtcagg aagaaagcca gcgtagtgta accgttatgc caggttggca
    80521 cggtgtcgat ttgatacacg caggtcatca tccagacgaa aatgacgccg agcgccatgc
    80581 tgacaagtaa ccagagtttc cccaacgctt gcggcatttt accgatgacc gccaccagcc
    80641 accatagtcc gccaacggca aaaaatatgg aaccggcagc aatctcgtta ctcagaccag
    80701 aagctccgat tcgattcagc gagttaaacg ctcgcagtgg cgatcccagg tgcatgacag
    80761 aggcaataaa cccgatgccc atcaacagcc agaggaaaaa catgccacgg acaatacgct
    80821 gacggtctgc gtcatttttg gcggcgaacc agccaattcc gctaacaatc agcgcgccta
    80881 ctacgcattg acccaatacg gtaaagataa ccagtggcca ctcatgccat ccatttccca
    80941 ttttacactt cctccggatt agccagataa ccagtggtat cgccggtcgg gcggctgttg
    81001 gcgttaggtt tgataacgat attgggtttt gtgaaatgcg cgcgcggcag tggcgcgacg
    81061 gcagccagag tgccgtgctt ctggcgcagc tcttcaattg gaccgaactc aagtgcacgc
    81121 agcgggcagg attcgacaca tatgggttgt ttcccctcgg cgacgcgcga ataacaacca
    81181 tcgcacttcg tcatgtgccc tttttcagca ttgtactgtg gcgcgccgta cggacaagcc
    81241 atgtggcagt agcggcagcc gatacaaaca tcttcatcaa ccaccacaaa gccatcttca
    81301 cgcttatgca ttgcgccgct ggggcagact tttgtacatg cggggtcatc gcaatggtta
    81361 caggagatgg agagataata agcgaacacg ttctggtgcc agacgccatt atcttcctgc
    81421 cagtcgccgc cagcgtattc ataaatacgg cggaaactga cttccgggcc aagatcttta
    81481 aaatctttgc acgccagttc gcaggtttta cagccagtac agcggctgga atcgataaaa
    81541 aatccatatt gtgtggtcat gggctactcc ttaaaccttt tcgatctgga caagattgct
    81601 gtgcgacggg tttccctttg ccagcggtga agggcggtga gaggtcagaa tattgatact
    81661 gccgccgtga tcgacccggt caccaaacat atccgcttta agccacgcac cttgcccgat
    81721 ggcggtaacg ccaggcagaa tacgcggagt cacttttgcg gcaatcagca tttctccatt
    81781 attgttaaat acccgcacgg tatcgccatg acggataccg cgtgcctgag catcaatggg
    81841 gttgatccac acctcttgtg ggcaggcctg ctgtaacaca tcaatattgc cgtagctgga
    81901 gtgggtacgc gctttgtagt ggaagcccgt taactgcagt ggataggttt tccgcagggg
    81961 atcgtcccag ccatcaaaac ctggggtata cgcaggaagg ggatgaataa tttcatcttt
    82021 tttcaattcc caggtatctg caatcttcgc cagtcgttcc gaataaattt cgattttccc
    82081 cgaaggtgtt ttcaacgggt ttgcctgtgg atcttcacgg aatgcgcgga aagcgacgta
    82141 gtgttcttcc gggcattttt tcttaaagat cccggtcgtt ttcatctcct cgtagtcggg
    82201 catctcaggg ttacgttcct tcgttttcgc atggagatat ttgatccatt catgctgact
    82261 gcgaccttca gtaaaggttt gataaacgtc tggtcctaag cgtttggcga cttcactcag
    82321 catccagtag atgggtttgc gttcaaattt tgctgaggtt gcgggttggg cgaggatcac
    82381 atagcccata ttccctgcag attcatgaga gataaggtct tcttgctctg ttggcatcag
    82441 gtcgggcaac aggatatcgc aatacttagc cgaggccgtc atgaagtggt caatgccaac
    82501 aatcatctcg cacttgctgt catcctgaag cacctcatgg gtgtgattga tgtcgccatg
    82561 ttgattgatc aatgtgttac tggcgtagca ccataaaaac ttgatgggga catccagttt
    82621 ttcttttcca cgaacaccat cacgggtcgc ggtcatttcc gtaccatggt cgatggcatc
    82681 tgtccatgta aagacggaaa tctgcgtttt aacaggattc tcaagcatcg ggaaccattc
    82741 tacccccaga tcccagctac cttcgcgtac acctgagttg ccgccgttta tgccgacgtt
    82801 accggtgaga acggaaagca tggcaatagc gcgggacgtt tgctcgccgt tggaatgtcg
    82861 ttgtggcccc caaccctgac aaatataagc aggttttgct gaaccgatct ctcgtgccaa
    82921 ctggataatt ttttctgccg ggatgctggt gatttttgct gcccattccg gcgttttagc
    82981 tatgccgtca ggcccttcgc ccagaatata ggctttataa tgcgcgttac gtggtgcgtt
    83041 ggcgggcagc gttttttcat cgtaaccaac acaatatttg tcgagaaatg gctgatcgac
    83101 catgttttca gtaatcagta cccaggcaat cgcacaggcc agtgcgccat cggtgcctgg
    83161 gcgaatgggc agccattcat cttcacgccc ggcagctgtg tcgttataac gtggatcgat
    83221 gacgatcatg cgtgcgtttg aacgttcgcg ggcttgctcg acgtagtaag tgacaccacc
    83281 gccgctcatc cgcgtttctg ccgggttatt tccgaacata acgaccagtt tcgtattggc
    83341 gatatcatcc gggctgttgc catcattggc accgaacata taactcattg cggcactgat
    83401 ctgtgcggta ctgtagctgc catagcgact gagaaaacca ccgcaagagt tcatcagacg
    83461 gtacgggacg tttgagttgg tgatgtttcc gccatctacg cctgttccgt acaggacatg
    83521 tacagcctca ttgccgtaat cttttaggat ccgccgaaga ttatcactga tggtatccag
    83581 ggcttcgtcc caacttatcc gttcaaattt accttcaccg cgcttgccga cgcgcttcat
    83641 gggatatttc aacctatcag gatgattcat ccgtcggcgg atagagcgcc cgcgtaaaca
    83701 cgcgcgaacc tgatgattac cgtagacgtc gtcacctgtc gtatcagact ccacccagta
    83761 cacggtgtca tctttcacat gcaaacgtaa cagacagcgg ctcccgcagt taacggtgca
    83821 ggaactccag accgctttct cttctaccgg agcctctgcc gcccggacca tttgagaaaa
    83881 tggcagagtg aaagcactgc ttgccagcgc aagactgcca agtgcggagg ttttcatcag
    83941 acttctacgg ctgatttcag ccttcatgag cgcctctgtg gtatggattt tcatcattac
    84001 tcacttattg cttttcaaac aaaatgtcat gccagaattt atggttgtcg tgggttatat
    84061 tttttcgatc tcgaccagat tagtgtgctg cgggtttccc ttcgccagtg gtgaagggcg
    84121 cagagtggtt agcgtattca cacagccgcc atggtcgatt ttatcgccag acatattggc
    84181 ctcgtgccag gctccctggc ccatagcgct aaccccaggg agaatgcgtg gtgtcacttt
    84241 ggctggtagc cgaacttcgc cacgatggtt aaacacccgc accatatcgc cgttggcaat
    84301 cccacgtttc tgcgcatcta tagggttgat ccacacctcc tgacggcagg cagccttcag
    84361 gagatcaata ttgccgtagg tcgagtgagt acgggatttg taatggaaac caaacagttg
    84421 aagtgggaag gttctacgtt caggggagtc ccagccttca aaggtagagg cataaactgg
    84481 cagtgggctt atcacttcat ctttttccag ttcccaggta cgggcaattt ccgccagctt
    84541 gctggaataa atttcaatct taccggaagg tgttttaagt ggatttgcct cggggtcgtc
    84601 acgaaatgct ttgtaggcga caaaatgacc attgggatct ttacgcttat agatacccat
    84661 ttttttcagt tcgtcgtaag acggtaacgc cggatctttg gcaagcattt tggcgtacag
    84721 atgttgtaac cattgttcct gcgtgcgacc ttcagtgaac ttttgataga cgtcaggtcc
    84781 aagacgtttc gcgacttcac tcaggatcca gtaaatcggt ttacgttcga atttttcgct
    84841 ggtgactggc tggaggaaaa tgagatatcc catgttaccg gcgtagtcgt taggaataat
    84901 atcttcctgc tcaacggtca tcaggtctgg cagcagaatg tcggcatatt ttgccgatga
    84961 ggtcataaag ttttcgatga ccacaatcat ttcgcatttc gattcgtctt gcagaatttc
    85021 atgcgttttg ttgatgtcag aatgctgatt aacgagggta tttcccgcgt agttccagat
    85081 gaacttaatg ggcacatcca gtttatcttt gccgcggacg ccgtcgcgga ttgccgtcat
    85141 ttgcggacca tgatcgatag catctgtcca gctgaagcag gagattgacg ttttgaccgg
    85201 attatccagc accggcaggc gttctatggt aatggtatag gtcgattcac gcgcgccact
    85261 atttccgccg ctgatgccga cattgcccgt caaaataggt aacatagcaa tagcgcgtgc
    85321 agtcagttcg ccgtttgcct ggcgttgcgg cccccagccc tggcagatat aagcgggttt
    85381 tgctgtgcca atttcacgcg ccagtttgat gatacggtct accgggatac cggtaatttg
    85441 cgaagcccac tgcggcgttt tcgctgtgtt atcatcacct tcaccaagaa tataggcttt
    85501 atagtgacca tttttgggtg catctgcggg taaggttttt tcgtcatagc cgacgcagta
    85561 tttatcgaga aaaggttgat caacgagatt ttcgttaatc aatacccagg caatacccgc
    85621 aaccagcgcg gcatcggtgc ccgggcgaat agggagccat tcatcttcac gaccagcagc
    85681 cgtatcggta tatcgcggat cgataacaat cattttggcg ttcgatttct cgcgcgcttt
    85741 ttcaagaaga taagtgatgc caccgccgct catgcgggtt tctgccgggt tgttaccaaa
    85801 catcacgacc agcttgctgt tttcaatatc cgtggtgctg ttgccatcat tactgccgta
    85861 ggtgtagggc atggcacagg aaatttgcgc ggtgctgtag gagccatact gattgagtga
    85921 accgccgtag cagttcatca ggcgtttgac cgccgaggct gatggcgaag agcgggtcat
    85981 attgccgcca acaatccccg aagagtactg aatatataca gccttattgc catattgttc
    86041 gacggttttt ttcaggctac tggcgatagt atccagggct tcatcccagc taatccgttc
    86101 gaatttgcct tcaccgcgtg tacccacgcg tttcattggg taattcaagc gatcgggatg
    86161 attaatacgc cggcggatgg agcgaccgcg caaacaggcg cgtacctgat ggttgccgta
    86221 ctcatcgctg ccggtattgt cagtttccac ccaggtcact tcattatctt taacatgtag
    86281 acgaagtgca cagcggctac cacagttgac ggaacaggca ccccagatca ctttttcgct
    86341 ggcctgttgt accgctgccg ctgcactgcg cagggtgaac ggtaaagaaa aaccgcctgc
    86401 agccagcgcc agagaaccta tcgcggttga tttaacgagt gttctgcggc tgatgcccac
    86461 cattcggtca tttttggaca taactcactc cctgttcttt atcgttatat aaatgtttat
    86521 a
//
LOCUS       DAPGUL010000007        86125 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.007, whole genome shotgun sequence.
ACCESSION   DAPGUL010000007 DAPGUL010000000
VERSION     DAPGUL010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 86125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 86125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..86125
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.007"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..159
                     /locus_tag="RHX21_000533"
     CDS             <1..159
                     /locus_tag="RHX21_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfL family protein"
                     /protein_id="HDV1985771.1"
                     /translation="FIKVALVGAVLATLTACTGHIENRDKNCSYDYLLHPAISISKII
                     GGCGPTAQ"
     gene            403..1791
                     /gene="frlA"
                     /locus_tag="RHX21_000534"
     CDS             403..1791
                     /gene="frlA"
                     /locus_tag="RHX21_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417829.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine/psicoselysine transporter"
                     /protein_id="HDV1985772.1"
                     /translation="MTANSPLQRIGQEKGIAMGSQELQRKLGFWAVLAIAVGTTVGSG
                     IFVSVGEVAKAAGTPWLTVLAFVIGGLIVIPQMCVYAELSTAYPENGADYVYLKNAGS
                     RPLAFLSGWASFWANDAPSLSIMALAIVSNLGFLTPIDPLLGKFIAAGLIIAFMLLHL
                     RSVEGGAAFQTLITIAKIIPFTIVIGLGIFWFKAENFAAPTTTAIGATGSFMALLAGI
                     SATSWSYTGMASICYMTGEIKNPGKTMPRALIGSCLLVLVLYTLLALVISGLMPFDKL
                     ANSETPISDALTWIPALGSTAGIFVAITAMIVILGSLSSCVMYQPRLEYAMAKDNLFF
                     KCFGHVHPKYNTPDVSIILQGALGIFFIFVSDLTSLLGYFTLVMCFKNTLTFGSIIWC
                     RKRDDYKPLWRTPAFGLMTTLAIASSLILVASTFVWAPIPGLICAVIVIATGLPAYAF
                     WAKRSRQLNALS"
     gene            1812..2834
                     /gene="frlB"
                     /locus_tag="RHX21_000535"
     CDS             1812..2834
                     /gene="frlB"
                     /locus_tag="RHX21_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417830.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-phosphate deglycase"
                     /protein_id="HDV1985773.1"
                     /translation="MLDIDKSTVDFLVTENMVQEVEKVLSHDVPLVHTIVEEMVKRDI
                     DRIYFVACGSPLNAAQTAKHLADRFSDLQVYAISGWEFCDNTPYRLDDRCAVIGVSDY
                     GKTEEVIKALELGRACGALTAAFTKRADSPITSAAEFSIDYQADCIWEIHLLLCYSVV
                     LEMITRLAPNAEIGKIKNDLKQLPNALGHLVRTWEEKGRQLGELASQWPMIYTVAAGP
                     LRPLGYKEGIVTLMEFTWTHGCVIESGEFRHGPLEIVEPGVPFLFLLGNDESRHTTER
                     AINFVKQRTDNVIVIDYAEISQGLHPWLAPFLMFVPMEWLCYYLSIYKDHNPDERRYY
                     GGLVEY"
     gene            2884..3714
                     /gene="frlC"
                     /locus_tag="RHX21_000536"
     CDS             2884..3714
                     /gene="frlC"
                     /locus_tag="RHX21_000536"
                     /EC_number="5.1.3.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 3-epimerase"
                     /protein_id="HDV1985774.1"
                     /translation="MKTGMFTCGHQRLPIEHAFRDASELGYDGIEIWGGRPHAFAPDL
                     KAGGIKQIKALAQTYQMPIIGYTPETNGYPYNMMLGDEHMRRESLDMIKLAMDMAKEM
                     NAGYTLISAAHAGYLTPPNVIWGRLAENLSELCEYAENIGMDLILEPLTPYESNVVCN
                     ANDVLHALALVPSPRLFSMVDICAPYVQAEPVMSYFDKLGDKLRHLHIVDSDGASDTH
                     YIPGEGKMPLRELMRDIIDRGYEGYCTVELVTMYMNEPRLYARQALERFRALLPEDER
                     "
     gene            3711..4496
                     /gene="frlD"
                     /locus_tag="RHX21_000537"
     CDS             3711..4496
                     /gene="frlD"
                     /locus_tag="RHX21_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HDV1985775.1"
                     /translation="MKTLATIGDNCVDIYPQLNKAFSGGNAVNVAVYCTRYGIQPGCI
                     TWVGDDDYGTKLKQDLARMGVDISHVHTKHGVTAQTQVELHDNDRVFGDYTEGVMADF
                     ALSEEDYAWLAQYDIVHAAIWGHAEDAFPQLHAAGKLTAFDFSDKWDSSLWQTLVPHL
                     DFAFASAPQEDEALRLKMKAIVARGAGVVIVTLGENGSIAWDGAQFWRQAPEPVTVID
                     TMGAGDSFIAGFLCGWSAGMTLPQAMAQGTACAAKTIQYHGAW"
     gene            4596..5327
                     /gene="phoB"
                     /locus_tag="RHX21_000538"
     CDS             4596..5327
                     /gene="phoB"
                     /locus_tag="RHX21_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417834.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator PhoB"
                     /protein_id="HDV1985776.1"
                     /translation="MSATDRYSHQLLYATVRQRLLDDIAQGVYQAGQQIPTENELCTQ
                     YNVSRITIRKAISDLVADGVLIRWQGKGTFVQSQKVENALLTVSGFTDFGVSQGKATK
                     EKVIEQERVSAAPFCEKLNIPGNSEVFHLCRVMYLDKEPLFIDSSWIPLSRYPDFDEI
                     YVEGSSTYQLFQERFDTRVVSDKKTIDIFAATRPQAKWLKCELGEPLFRISKIAFDQN
                     DKPVHVSELFCRANRITLTIDNKRH"
     gene            complement(5479..6564)
                     /locus_tag="RHX21_000539"
     CDS             complement(5479..6564)
                     /locus_tag="RHX21_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDV1985777.1"
                     /translation="MKTFPLQSLTIIEAQQKQFALVDSICRHFPGSEFLTGGDLGLTP
                     GLNQPRVTQRVEQVLADAFHAQAAALVQGAGTGAIRAGLAALLKPGQRLLVHDAPVYP
                     TTRVIIEQMGLTLITVDFNDLSALKQVVDEQQPDAALVQHTRQQPQDSYVLADVLATL
                     RAAGVPALTDDNYAVMKVARIGCECGANVSTFSCFKLFGPEGVGAVVGDADVINRIRA
                     TLYSGGSQIQGAQALEVLRGLVFAPVMHAVQAGVSERLLALLNGGAVPEVKSAVIANA
                     QSKVLIVEFHQPIAARVLEEAQKRGALPYPVGAESKYEIPPLFYRLSGTFRQANPQSE
                     HCAIRINPNRSGEETVLRILRESIASI"
     gene            complement(6576..7880)
                     /locus_tag="RHX21_000540"
     CDS             complement(6576..7880)
                     /locus_tag="RHX21_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfT family protein"
                     /protein_id="HDV1985778.1"
                     /translation="MDLYIQIIVVACLTGMTSLLAHRSAAVFHDGIRPILPQLIEGYM
                     NRREAGSIAFGLSIGFVASVGISFTLKTGLLNAWLLFLPTDILGVLAINSLMAFGLGA
                     IWGVLILTCLLPVNQLLTALPVDVLGSLGELSSPVVSAFALFPLVAIFYQFGWKQSLI
                     AAVVVLMTRVVVVRYFPHLNPESIEIFIGMVMLLGIAITHDLRHRDENDIDASGLSVF
                     EERTSRIIKNLPYIAIVGALIAAVASMKIFAGSEVSIFTLEKAYSAGVTPEQSQTLIN
                     QAALAEFMRGLGFVPLIATTALATGVYAVAGFTFVYAVGYLSPNPMVAAVLGAVVISA
                     EVLLLRSIGKWLGRYPSVRNASDNIRNAMNMLMEVALLVGSIFAAIKMAGYTGFSIAV
                     AIYFLNESLGRPVQKMAAPVVAVMITGILLNVLYWLGLFVPA"
     gene            complement(7892..8245)
                     /locus_tag="RHX21_000541"
     CDS             complement(7892..8245)
                     /locus_tag="RHX21_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417837.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2620 domain-containing protein"
                     /protein_id="HDV1985779.1"
                     /translation="MKKIGVAGLQREQIKKTIEATAPGSFEVFIHNDMEAAMKVKSGQ
                     LDYYIGACNTGAGAALSIAIAVIGYNKSCTIAKPGIKAKDEHIAKMIAEGKVAFGLSV
                     EHVEHAIPMLINHLK"
     gene            complement(8256..9134)
                     /locus_tag="RHX21_000542"
     CDS             complement(8256..9134)
                     /locus_tag="RHX21_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotriesterase-related protein"
                     /protein_id="HDV1985780.1"
                     /translation="MSIDPTGYTLAHEHLHIDLSGFKNNVDCRLDQYAFICQEMNDLM
                     TRGVRNVIEMTNRYMGRNAQFMLDVMRETGINVVACTGYYQDAFFPEHVATRSVQELA
                     QEMVDEIEQGIDGTDLKAGIIAEIGSSEGKITPLEEKVFIAAALAHNQTGRPISTHTS
                     FSTMGLEQLALLQAHGVDLSRVTVGHCDLKDNLDNILKMIDLGAYVQFDTIGKNSYYP
                     DEKRIAMLHALRDRGLLNRVMLSTDITRRSHLKANGGYGYDYLLTTFIPQLRQSGFSQ
                     ADVDVMLRENPSQFFQ"
     gene            complement(9131..10357)
                     /locus_tag="RHX21_000543"
     CDS             complement(9131..10357)
                     /locus_tag="RHX21_000543"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDV1985781.1"
                     /translation="MARFVVLVIDSFGVGAMKDVTLVRPQDAGANTCGHILSQLPHLQ
                     LPTLEKLGLINALGYAPGDMQPSDSATWGVAELQHEGGDTFMGHQEILGTRPLPPLRM
                     PFCDVIDRVEQALVSAGWQVERRGDELQFLWVNQAVAIGDNLEADLGQVYNITANLSV
                     ISFDDAIKIGRIVREQVQVGRVITFGGLLTDSQRLLDAAESKEGRFIGINAPRSGAYD
                     NGFQVVHMGYGVDEKVQVPQKLYEAGVPTVLVGKVADIVNNPYGVSWQNLVDSQRIMD
                     ITLDEFNTHPTAFICINIQETDLAGHAEDVARYAERLQVVDRNLARLVEAMQPDDCLV
                     VMADHGNDPTIGHSHHTREVVPVLVYQQGLVHTQLGVRTTLSDVGATVCEFFRAPPPQ
                     NGRSFLSSLRFAGDTL"
     gene            complement(10357..11520)
                     /locus_tag="RHX21_000544"
     CDS             complement(10357..11520)
                     /locus_tag="RHX21_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfX family PLP-dependent enzyme"
                     /protein_id="HDV1985782.1"
                     /translation="MFVEALKRQNPALISAALSLWQQGKIAPDSWVIDVDQILENGKR
                     LIETARLYGIELYLMTKQFGRNPWLAEKLLALGYSGIVAVDYKEARVMRRAGLPVAHQ
                     GHLVQIPCHQVADAVEQGTDVITVFTLDKAREVSAAAVKAGRIQSVLLKVYSDDDFLY
                     PGQESGFVQHSLHEVVAEIKKLPGLHLAGLTHFPCLLWDEAAGKVLPTPNLHTLVQAR
                     DQLAKSGIAIEQLNAPSATSCTSLPLLAQYGVTHAEPGHALTGTIPANQQGDQPERIA
                     MLWLSEISHHFRGDSYCYGGGYYRRGHAQHALVFTPENQKITETNLKTVDDSSIDYTL
                     PLAGEYPVSSAVVLCFRTQIFVTRSDVVLVSGIHRGEPKIVGRYDSLGNSLGA"
     gene            complement(11604..11966)
                     /locus_tag="RHX21_000545"
     CDS             complement(11604..11966)
                     /locus_tag="RHX21_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417841.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDV1985783.1"
                     /translation="METRLNLLCEAGVIDKDICKGMMQVVNVLETECHLPVRSEQGTM
                     AMTHMASALMRSRRGEEIEPLDNELLAELAQSSHWQAVVQLHQVLLKEFALEVNPCEE
                     GYLLANLYGLWMAANEEV"
     gene            complement(11983..12888)
                     /locus_tag="RHX21_000546"
     CDS             complement(11983..12888)
                     /locus_tag="RHX21_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1985784.1"
                     /translation="MRRTFIKKEGVVITTLARYLLGEKCGNRLKTIDELATECRSSVG
                     LTQAALKTLESSGAIRIERRGRNGSYLVEMDNKALLSHVDINNVVCAMPLPYTRLYEG
                     LASGLKAQFDGIPFYYAHMRGADIRVECLLNGVYDMAVVSRLAAESYLTQKGLCLALE
                     LGPHTYVGEHQLICRKGESANVKRVGLDNRSADQKIMTDVFFGGSDVERVDLSYHESL
                     QRIVKGDVDAVIWNVVAENELTMLGLEATPLTDDPRFLQATEAVVLTRVDDYPMQQLL
                     RAVVDKHALLAHQQRVVSGEQEPSY"
     gene            complement(13157..14161)
                     /gene="trpS"
                     /locus_tag="RHX21_000547"
     CDS             complement(13157..14161)
                     /gene="trpS"
                     /locus_tag="RHX21_000547"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HDV1985785.1"
                     /translation="MTKPIVFSGAQPSGELTIGNYMGALRQWVNMQDDYHCIYCIVDQ
                     HAITVRQDAQKLRKATLDTLALYLACGIDPEKSTIFVQSHVPEHAQLGWALNCYTYFG
                     ELSRMTQFKDKSARYAENINAGLFDYPVLMAADILLYQTNLVPVGEDQKQHLELSRDI
                     AQRFNALYGEIFKVPEPFIPKSGARVMSLLEPTKKMSKSDDNRNNVIGLLEDPKSVVK
                     KIKRAVTDSDEPPVVRYDVQNKAGVSNLLDILSAVTGQSIPELEKQFEGKMYGHLKGE
                     VADAVSGMLTELQERYHRFRNDEAFLQQVMKDGAEKASVHASRTLKAVYEAIGFVAKP
                     "
     gene            complement(14154..14912)
                     /gene="gph"
                     /locus_tag="RHX21_000548"
     CDS             complement(14154..14912)
                     /gene="gph"
                     /locus_tag="RHX21_000548"
                     /EC_number="3.1.3.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycolate phosphatase"
                     /protein_id="HDV1985786.1"
                     /translation="MNKFEDIRGVAFDLDGTLVDSAPGLAAAVDMALYALELPVAGEE
                     RVITWIGNGADVLMERALTWARQERATQRKTMGKPPVDDDIPAEEQVRILRKLFDRYY
                     GEVAEEGTFLFPHAADTLGALQAKGLPLGLVTNKPTPFVAPLLEALDIAKYFSVVIGG
                     DDVQNKKPHPDPLLLVAERMGIAPQQMLFVGDSRNDIQAAKAAGCPSVGLTYGYNYGE
                     AIDLSQPDVIYQSINDLLPALGLPHSENQESKND"
     gene            complement(14905..15582)
                     /gene="rpe"
                     /locus_tag="RHX21_000549"
     CDS             complement(14905..15582)
                     /gene="rpe"
                     /locus_tag="RHX21_000549"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDV1985787.1"
                     /translation="MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVP
                     NLTIGPMVLKSLRNYGITAPIDVHLMVKPVDRIVPDFAAAGASIITFHPEASEHVDRT
                     LQLIKENGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFIPQTLDKLRE
                     VRRRIDESGFDIRLEVDGGVKVNNIGEIAAAGADMFVAGSAIFDQPDYKKVIDEMRSE
                     LAKVSHE"
     gene            complement(15600..16436)
                     /gene="dam"
                     /locus_tag="RHX21_000550"
     CDS             complement(15600..16436)
                     /gene="dam"
                     /locus_tag="RHX21_000550"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine-specific DNA-methyltransferase"
                     /protein_id="HDV1985788.1"
                     /translation="MKKNRAFLKWAGGKYPLLDDIKRHLPKGECLVEPFVGAGSVFLN
                     TDFSRYILADINSDLISLYNIVKMRTDEYVQAARELFVPETNCAEVYYQFREEFNKSQ
                     DPFRRAVLFLYLNRYGYNGLCRYNLRGEFNVPFGRYKKPYFPEAELYHFAEKAQNAFF
                     YCESYADSMARADDASVVYCDPPYAPLSATANFTAYHTNSFTLEQQAHLAEIAEGLVE
                     RHIPVLISNHDTMLTREWYQRAKLHVVKVRRSISSNGGTRKKVDELLALYKPGVVSPA
                     KK"
     gene            complement(16543..17829)
                     /gene="damX"
                     /locus_tag="RHX21_000551"
     CDS             complement(16543..17829)
                     /gene="damX"
                     /locus_tag="RHX21_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DamX"
                     /protein_id="HDV1985789.1"
                     /translation="MDEFKPEDELKPDPSDRRTGRSRQSSERSERTERGEPQINFDDI
                     ELDDTDDRRPTRAQKERNEEPEIEEEIDESEDETVDEERVERRPRKRKKAASKPASRQ
                     YMMMGVGILVLLLLIIGIGSALKAPSTSSSDQTASGEKSIDLAGNATDQANGVQPAPG
                     TTSAENTQQDVSLPPISSTPTQGQTPAATDGQQRVEVQGDLNNALTQPQNQQQLNNVA
                     VNSTLPTEPATVAPVRNGNASRDTAKTQTAERPATTRPARQQAVIEPKKPQATVKTEP
                     KPVAQTPKRTEPAAPVASTKAPAATSAPAPKETATTAPVQTASPAQTTATPAAGGKTA
                     GNVGSLKSAPSSHYTLQLSSSSNYDNLNGWAKKENLKNYVVYETTRNGQPWYVLVSGV
                     YASKEEAKKAVSTLPADVQAKNPWAKPLRQVQADLK"
     gene            complement(17921..19009)
                     /gene="aroB"
                     /locus_tag="RHX21_000552"
     CDS             complement(17921..19009)
                     /gene="aroB"
                     /locus_tag="RHX21_000552"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HDV1985790.1"
                     /translation="MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNET
                     LAPLYLDKVRGVLEQAGVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVAL
                     GGGVVGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
                     ASVVVDLDCLKTLPPRELASGLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYC
                     IRRCCELKAEVVAADERETGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAA
                     RTSERLGQFSSAETQRIITLLKRAGLPVNGPREMSAQAYLPHMLRDKKVLAGEIRLIL
                     PLAIGKSEVRSGVSHELVLNAIADCQSA"
     gene            complement(19066..19587)
                     /gene="aroK"
                     /locus_tag="RHX21_000553"
     CDS             complement(19066..19587)
                     /gene="aroK"
                     /locus_tag="RHX21_000553"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004709337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase AroK"
                     /protein_id="HDV1985791.1"
                     /translation="MAEKRNIFLVGPMGAGKSTIGRQLAQQLNMEFYDSDQEIEKRTG
                     ADVGWVFDLEGEEGFRDREEKVINELTEKQGIVLATGGGSVKSRETRNRLSARGVVVY
                     LETTIEKQLARTQRDKKRPLLHVETPPREVLEALANERNPLYEEIADVTIRTDDQSAK
                     VVANQIIHMLESN"
     gene            complement(19988..21226)
                     /gene="hofQ"
                     /locus_tag="RHX21_000554"
     CDS             complement(19988..21226)
                     /gene="hofQ"
                     /locus_tag="RHX21_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA uptake porin HofQ"
                     /protein_id="HDV1985792.1"
                     /translation="MKQWIAALLLMLIPGVQAAKPQKVTLMVDDVPVAQVLQALAEQE
                     KLNLVVSPDVSGTVSLHLTDVPWKQALQTVVKSAGLITRQEGNILSVHSIAWQNDNIA
                     RQEAEQARAQANLPLENRSITLQYADAGELAKAGEKLLSAKGSMTVDKRTNRLLLRDN
                     KTALSALEQWVAQMDLPVGQVELSAHIVTINEKSLRELGVKWTLADAQHAGGVGQVTT
                     LGSDLSVATATTHVGFNIGRINGRLLDLELSALEQKQQLDIIASPRLLASHLQPASIK
                     QGSEIPYQVSSGESGATSVEFKEAVLGMEVTPTVLQKGRIRLKLHISQNVPGQVLQQA
                     DGEVLAIDKQEIETQVEVKSGETLALGGIFTRKNKSGQDSVPLLGDIPWFGQLFRHDG
                     KEDERRELVVFITPRLVSSE"
     gene            complement(21138..21542)
                     /gene="hofP"
                     /locus_tag="RHX21_000555"
     CDS             complement(21138..21542)
                     /gene="hofP"
                     /locus_tag="RHX21_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417851.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofP"
                     /protein_id="HDV1985793.1"
                     /translation="MRVKRWLLAGIALCLLTGMRDPFKPPEDLCRISELSQWRYQGMV
                     GRGERIIGVIKDGQKKWRRVQQNDVLENGWTILQLTPDVLTLGTGTNCEPPQWLWQRQ
                     GDTNEAMDSRTTVDADTRRTGGKAAKSDADGG"
     gene            complement(21532..21972)
                     /gene="hofO"
                     /locus_tag="RHX21_000556"
     CDS             complement(21532..21972)
                     /gene="hofO"
                     /locus_tag="RHX21_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofO"
                     /protein_id="HDV1985794.1"
                     /translation="MNMFFDWWFATSPRLRQLCWAFWLLMLVTLIFLSSTHHEERDAL
                     IRLRASHHQQWAALYRLVDTTPFSEEKTLPFSPLDFQLSGAQLVSWHPSAQGGELALK
                     TLWEAVPSAFTRLAERNVSVSRFSLSVEGDDLLFTLQLETPHEG"
     gene            complement(21956..22495)
                     /gene="hofN"
                     /locus_tag="RHX21_000557"
     CDS             complement(21956..22495)
                     /gene="hofN"
                     /locus_tag="RHX21_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofN"
                     /protein_id="HDV1985795.1"
                     /translation="MNPPINFLPWRQQRRTAFLRFWLLMFVAPLLLAVGITLILRLTG
                     SAEARIDAVLLQAEQQLARSLQITKPRLLEQQQLREQRSQRQRQRQFTRDWQSALEAL
                     AALLPEHAWLTTISWQQGTLEIKGLTTSITALNALETSLRQDASFHLNQRGATQQDAQ
                     GRWQFEYQLTRKVSDEHVL"
     gene            complement(22495..23274)
                     /gene="hofM"
                     /locus_tag="RHX21_000558"
     CDS             complement(22495..23274)
                     /gene="hofM"
                     /locus_tag="RHX21_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417854.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofM"
                     /protein_id="HDV1985796.1"
                     /translation="MAFKIWQIGLHLQQQEAVAVAIVRGAKECFLQRWWRLPLENDII
                     KDGRIVDAQQLAKTLLPWSRELPQRHHIMLAFPASRTLQRSFPRPSMSLGEREQTAWL
                     SGTMARELDMDPDSLRFDYSEDSLSPAYNVTAAQSKELATLLTLAERLRVHVSAITPD
                     ASALQQFLPFLPSHQQCLAWRDNEQWLWATRCRWGRKLAVGMTSAKELAAALSVDPES
                     VAICGEGGFDPWEAVSVRQPPLPPPGGDFAIALGLALGKAY"
     gene            23394..25946
                     /gene="mrcA"
                     /locus_tag="RHX21_000559"
     CDS             23394..25946
                     /gene="mrcA"
                     /locus_tag="RHX21_000559"
                     /EC_number="2.4.1.129"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417855.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase/peptidoglycan
                     DD-transpeptidase MrcA"
                     /protein_id="HDV1985797.1"
                     /translation="MKFVKYFLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRL
                     QIPMQIYSADGELIAQYGEKRRIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIF
                     RAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEIL
                     ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRA
                     VARRNVVLSRMLDEGYITQQQFDQTRTEAINANYHAPEIAFSAPYLSEMVRQEMYNRY
                     GESAYEDGYRIYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPANVLWKVGESAWDNN
                     KITDTLKALPTYGPLLPAAVTSANPQQATAMLADGSTVALSMEGVRWARPYRSDTQQG
                     PTPRKVTDVLQTGQQIWVRQVGDAWWLAQVPEVNSALVSINPQNGAVMALVGGFDFNQ
                     SKFNRATQALRQVGSNIKPFLYTAAMDKGLTLASMLNDVPISRWDAGAGSDWQPKNSP
                     PQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTESLALGSA
                     SFTPMQVARGYAVMANGGFLVDPWFISKIENDQGGVIFEAKPKVACPECDIPVIYGDT
                     QKSNVLENNDVEDVAISREQQNVSVPMPQLEQANQALVAKTGAQEYAPHVINTPLAFL
                     IKSALNTNIFGEPGWQGTGWRAGRDLQRRDIGGKTGTTNSSKDAWFSGYGPGVVTSVW
                     IGFDDHRRNLGHTTASGAIKDQISGYEGGAKSAQPAWDAYMKAVLEGVPEQPLTPPPG
                     IVTVKIDRSTGQLANGGNSREEYFIEGTQPTQQAVHEVGTTIIDNGEAQELF"
     gene            complement(26114..26674)
                     /gene="nudE"
                     /locus_tag="RHX21_000560"
     CDS             complement(26114..26674)
                     /gene="nudE"
                     /locus_tag="RHX21_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP compounds hydrolase NudE"
                     /protein_id="HDV1985798.1"
                     /translation="MSKSLQKPTILNVETVARSRLFTVESVDLEFSNGVRRVYERMRP
                     TNREAVMIVPIVDDHLILIREYAVGTESYELGFSKGLIDPGESVYEAANRELKEEVGF
                     GANDLTFLKKLSMAPSYFSSKMNIVVAQDLYPESLEGDEPEPLPQVRWPLAHMMDLLE
                     DPDFNEARNVSALFLVREWLKGQGRV"
     gene            26994..29129
                     /gene="igaA"
                     /locus_tag="RHX21_000561"
     CDS             26994..29129
                     /gene="igaA"
                     /locus_tag="RHX21_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular growth attenuator protein IgaA"
                     /protein_id="HDV1985799.1"
                     /translation="MSTIVIFLAALLACSLLAGWLIKVRSRRRQLPWTNAFADAQTRK
                     LTPEERSAVENYLESLTQVLQVPGPTGASAAPISLALNAESNNVMMLTHAITRYGIST
                     DDPNKWRYYLDSVEVHLPPFWEQYINDENTVELIYTDSLPLVISLNGHTLQEYMQETR
                     GYALQPVPSTQASIRGEESEQIELLNIRKETHEEYALSRPRGLREALLIVASFLMFFF
                     CLITPDVFVPWLAGGALLLLGAGLWGLFAPPAKSSLREIHCLRGTPRRWGLFGENDQE
                     QINNISLGIIDLVYPAHWQPYIAQDLGQQTDIDIYLDRHVVRQGRYLSLHDEVKNFPL
                     QHWLRSTIIAAGSLLVLFMLLFWIPLDIPLKFTLSWMKGAQTIEATSVKQLADAGVRV
                     GDTLRISGTGMCNIRTSGTWSAKTNSPFLPFDCSQIIWNDARSLPLPESELVNKATAL
                     TEAVNRQLHPKPEDESRVSASLRSAIQKSGMVLLDDFGDIVLKTADLCSAKDDCVRLK
                     NALVNLGNSKDWDALVKRANAGKLDGVNVLLRPVSAESLDNLVATSTAPFITHETARA
                     AQSLNSPAPGGFLIVSDEGSDFVDQPWPSASLYDYPPQEQWNAFQKLAQMLMHTPFNA
                     EGIVTKIFTDANGTQHIGLHPIPDRSGLWRYLSTTLLLLTMLGSAIYNGVQAWRRYQR
                     HRTRMMEIQAYYESCLNPQLITPSESLIE"
     gene            29194..29862
                     /gene="yrfG"
                     /locus_tag="RHX21_000562"
     CDS             29194..29862
                     /gene="yrfG"
                     /locus_tag="RHX21_000562"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312268.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP/IMP nucleotidase"
                     /protein_id="HDV1985800.1"
                     /translation="MHINIAWQDVDTVLLDMDGTLLDLAFDNYFWQKLVPETWGAKNG
                     VTPQEAMEYMRQQYHDVQHTLNWYCLDYWSEQLGLDICAMTTEMGPRAVLREDTIPFL
                     EALKASGKQRILLTNAHPHNLAVKLEHTGLDAHLDLLLSTHTFGYPKEDQRLWHAVAE
                     ATGLKAERTLFIDDSEAILDAAAQFGIRYCLGVTNPDSGIAEKQYQRHPSLNDYRRLI
                     PSLM"
     gene            29873..30274
                     /gene="hslR"
                     /locus_tag="RHX21_000563"
     CDS             29873..30274
                     /gene="hslR"
                     /locus_tag="RHX21_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated heat shock protein Hsp15"
                     /protein_id="HDV1985801.1"
                     /translation="MKEKPAVEVRLDKWLWAARFYKTRALAREMIEGGKVHYNGQRSK
                     PSKIVELNATLTLRQGNDERTVIVKAITEQRRPASEAALLYEETAESVEKREKMAMAR
                     KLNALTMPHPDRRPDKKERRDLLRFKHGDSE"
     gene            30299..31177
                     /gene="hslO"
                     /locus_tag="RHX21_000564"
     CDS             30299..31177
                     /gene="hslO"
                     /locus_tag="RHX21_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417860.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HDV1985802.1"
                     /translation="MPQHDQLHRYLFENFAVRGELVTVSETLQQILENHDYPQPVKNV
                     LAELLVATSLLTATLKFDGDITVQLQGDGPMNLAVINGNNNQQMRGVARVQGEIPENA
                     DLKTLVGNGYVVITITPSEGERYQGVVGLEGDTLAACLEDYFMRSEQLPTRLFIRTGD
                     VDGKPAAGGMLLQVMPAQNAQQDDFDHLATLTETIKTEELLTLPANEVLWRLYHEEEV
                     TVYDPQDVEFKCTCSRERCADALKTLPDEEVDSILAEDGEIDMHCDYCGNHYLFNAMD
                     IAEIRNNASPADPQVH"
     gene            complement(31312..33036)
                     /locus_tag="RHX21_000565"
     CDS             complement(31312..33036)
                     /locus_tag="RHX21_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4153 domain-containing protein"
                     /protein_id="HDV1985803.1"
                     /translation="MDNVELSPATRWGMIATGLLQGLVCYLLIAWLAGKNHSWIVYGV
                     PATVAFSSVLLFSVISFKQKRLWGWLALVFIATLGMSGWLKWQTDGMNPWRAEKAIWD
                     FGCYLLLMAMLLLPWIQQSLRIRNDSSRYRYFYQSVWHNVLILLVIFLANGLTWLVLL
                     LWGELFKLVGIKFFNTLFFATDWFMYLTLGLVTALAVILARTQSRLIDSIQKLFTLIA
                     TGLLPLVSLLTLMFIITLPFTGLSAISRHISAAGLLLTLAFLQLILMVIVRDPQKASL
                     PWTGPLRCLIKTALLVAPLYVFVAAWALWLRVAQYGWTVDRLQGALAVLVLLVWSLGY
                     FVSIVWRNGQNPLVLQGKVNLAVSLLVLVILVLLNSPVLDSMRISVNSHMARYQSGKN
                     TPDQVTIYMLEQSGRYGRAALESLKSDAGFMKDPKRARDLLMALDGEQHLQEQVSEKV
                     LAENVLIAPGSVKPDATFWSALIQDRYNVMTCIEKDACVLVEQDLNSDGQAERILFAF
                     NDDRVIVYGFDSDRKEWDALDMSLLPNEITKEKLLTAAKDGKLGTRPKAWRDLTVDGE
                     TLEINLSK"
     gene            33415..35037
                     /gene="pckA"
                     /locus_tag="RHX21_000566"
     CDS             33415..35037
                     /gene="pckA"
                     /locus_tag="RHX21_000566"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HDV1985804.1"
                     /translation="MRVNNGLTPQELEAYGISDVHDIVYNPSYDLLYQEELDPSLTGY
                     ERGVLTNLGAVAVDTGIFTGRSPKDKYIVRDDTTRDTFWWADKGKGKNDNKPLSPETW
                     QHLKGLVTRQLSGKRLFVVDAFCGANPDTRLSVRFITEVAWQAHFVKNMFIRPSDEEL
                     AGFKPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERMQLIGGTWYGGEMKKGMFSM
                     MNYLLPLKGIASMHCSANVGEKGDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDD
                     GVFNFEGGCYAKTIKLSKEAEPEIYNAIRRDALLENVTVREDGTIDFDDGSKTENTRV
                     SYPIYHIDNIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTADQTQYHFLSGFTAKLA
                     GTERGITEPTPTFSACFGAAFLSLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRI
                     SIKDTRAIIDAILNGSLDNAETFTLPMFNLAIPTELPGVDTKILDPRNTYASPEQWQE
                     KAETLAKLFIDNFDKYTDTPAGAALVAAGPKL"
     gene            35154..35471
                     /locus_tag="RHX21_000567"
     CDS             35154..35471
                     /locus_tag="RHX21_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDV1985805.1"
                     /translation="MFTFIELQGFSKRRQLLLPDDEFRAFQELLIQDPTAGDIIAGTG
                     SFRKIRWNRSGMGKRGGIRIIYYNVTRNGRIYLALIYPKNEQDDLTEEQRKALKLLSE
                     KLL"
     gene            35530..35826
                     /locus_tag="RHX21_000568"
     CDS             35530..35826
                     /locus_tag="RHX21_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDV1985806.1"
                     /translation="MKDELFADLLASAEEMVRIEKGEETPEPEHVHTFSEIDVKAIRE
                     ATGLRQQDFAVAVGVSYDLVKSWETKRRQPTGAPRKLLLLLQANPFIINQLKTI"
     gene            complement(35858..37210)
                     /gene="envZ"
                     /locus_tag="RHX21_000569"
     CDS             complement(35858..37210)
                     /gene="envZ"
                     /locus_tag="RHX21_000569"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     EnvZ"
                     /protein_id="HDV1985807.1"
                     /translation="MRRLRFSPRSSFARTLLLIVTLLFASLVTTYLVVLNFAILPSLQ
                     QFNKVLAYEVRMLMTDKLQLEDGTQLVVPPAFRREIYRELGISLYSNEAAEEAGLRWA
                     QHYEFLSHQMAQQLGGPTEVRVEVNKSSPVVWLKTWLSPNIWVRVPLTEIHQGDFSPL
                     FRYTLAIMLLAIGGAWLFIRIQNRPLVDLEHAALQVGKGIIPPPLREYGASEVRSVTR
                     AFNHMAAGVKQLADDRTLLMAGVSHDLRTPLTRIRLATEMMSEQDGYLAESINKDIEE
                     CNAIIEQFIDYLRTGQEMPMEMADLNAVLGEVIAAESGYEREIETALYPGSIEVKMHP
                     LSIKRAVANMVVNAARYGNGWIKVSSGTEPNRAWFQVEDDGPGIAPEQRKHLFQPFVR
                     GDSARTISGTGLGLAIVQRIVDNHNGMLELGTSERGGLSIRAWLPVPVTRAQGTTKEG
                     "
     gene            complement(37207..37926)
                     /gene="ompR"
                     /locus_tag="RHX21_000570"
     CDS             complement(37207..37926)
                     /gene="ompR"
                     /locus_tag="RHX21_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator OmpR"
                     /protein_id="HDV1985808.1"
                     /translation="MQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLL
                     TRESFHLMVLDLMLPGEDGLSICRRLRSQSNPMPIIMVTAKGEEVDRIVGLEIGADDY
                     IPKPFNPRELLARIRAVLRRQANELPGAPSQEEAVIAFGKFKLNLGTREMFREDEPMP
                     LTSGEFAVLKALVSHPREPLSRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAH
                     PRYIQTVWGLGYVFVPDGSKA"
     gene            38154..38630
                     /gene="greB"
                     /locus_tag="RHX21_000571"
     CDS             38154..38630
                     /gene="greB"
                     /locus_tag="RHX21_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312275.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreB"
                     /protein_id="HDV1985809.1"
                     /translation="MKTPLVTREGYEKLKQELNYLWREERPEVTKKVTWAASLGDRSE
                     NADYQYNKKRLREIDRRVRYLTKCMENLKIVDYSPQQEGKVFFGAWVEIENDDGVTHR
                     FRIVGYDEIFGRKDYISIDSPMARALLKKEVGDLAVVNTPAGEASWYVNAIEYVKP"
     gene            38727..41048
                     /locus_tag="RHX21_000572"
     CDS             38727..41048
                     /locus_tag="RHX21_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417866.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HDV1985810.1"
                     /translation="MMNDSFCRIIAGEIQARPEQVDAAVRLLDEGNTVPFIARYRKEI
                     TGGLDDTQLRNLETRLGYLRELEERRQAILKSISEQGKLTDELANAINATLSKTELED
                     LYLPYKPKRRTRGQIAIEAGLEPLADLLWSDPSHTPEVAAAQYVDADKGVADTKAALD
                     GARYILMERFAEDAALLAKVRDYLWKNAHLVSTVVSGKEEEGAKFRDYFDHHEPLSTV
                     PSHRALAMFRGRNEGVLQLSLNADPQFDEPPKESYCEQIIMDHLGLRLNNAPADSWRK
                     GVVSWTWRIKVLMHLETELMGTVRERAEDEAINVFARNLHDLLMAAPAGLRATMGLDP
                     GLRTGVKVAVVDATGKLVATDTIYPHTGQAAKAAMTVAALCEKHNVELVAIGNGTASR
                     ETERFYLDVQKQFPKVTAQKVIVSEAGASVYSASELAAQEFPDLDVSLRGAVSIARRL
                     QDPLAELVKIDPKSIGVGQYQHDVSQTQLARKLDAVVEDCVNAVGVDLNTASVPLLTR
                     VAGLTRMMAQNIVAWRDENGQFQNRQQLLKVSRLGPKAFEQCAGFLRINHGDNPLDAS
                     TVHPEAYPVVERILAATQQALKDLMGNSSELRNLKASDFTDEKFGVPTVTDIIKELEK
                     PGRDPRPEFKTAQFADGVETMNDLQPGMILEGAVTNVTNFGAFVDIGVHQDGLVHISS
                     LSNKFVEDPHTVVKAGDIVKVKVLEVDLQRKRIALTMRLDEQPGETNARRGGGNERPQ
                     NNRPAAKPRGREAQPAGNSAMMDALAAAMGKKR"
     gene            41486..41713
                     /gene="feoA"
                     /locus_tag="RHX21_000573"
     CDS             41486..41713
                     /gene="feoA"
                     /locus_tag="RHX21_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transporter A"
                     /protein_id="HDV1985811.1"
                     /translation="MQYTPDTAWKITGFSREISPAYRQKLLSLGMLPGSSFNVVRVAP
                     LGDPIHIETRRVSLVLRKKDLALLEVEAVSC"
     gene            41730..44051
                     /gene="feoB"
                     /locus_tag="RHX21_000574"
     CDS             41730..44051
                     /gene="feoB"
                     /locus_tag="RHX21_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(2+) transporter permease subunit FeoB"
                     /protein_id="HDV1985812.1"
                     /translation="MKKLTIGLIGNPNSGKTTLFNQLTGARQRVGNWAGVTVERKEGQ
                     FSTTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHYILSGDADLLINVVDASNLERNL
                     YLTLQLLELGIPCIVALNMLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALK
                     LAIDRYKANENVELVHYAQPLLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAY
                     AGEASQHLDAALARLRNEMDDPALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDK
                     IVLNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDVGSVALFVHGIQWIGYTLHFPDW
                     LTIFLAQGLGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGK
                     SFVPLIVGFGCNVPSVMGARTLDAPRERLMTIMMAPFMSCGARLAIFAVFAAAFFGQN
                     GALAVFSLYMLGIVMAVLTGLMLKYTIMRGEATPFVMELPVYHVPHVKSLIIQTWQRL
                     KGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVDNINDSALASVSRVITPVFKPIGVHED
                     NWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDEEFNPAEFNLGEELFSAIDETWQSL
                     KDTFSLSVLMNPIEASKGDGEMGTGAMGVMDQKFGSAAAAYSYLIFVLLYVPCISVMG
                     AIARESSRGWMGFSILWGLNIAYSLATLFYQVASYSQHPTYSLVCILAVILFNIVVIG
                     LLRRARSRVDIELLATRKSVSSCCAASTTGDCH"
     gene            44051..44287
                     /gene="feoC"
                     /locus_tag="RHX21_000575"
     CDS             44051..44287
                     /gene="feoC"
                     /locus_tag="RHX21_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[Fe-S]-dependent transcriptional repressor FeoC"
                     /protein_id="HDV1985813.1"
                     /translation="MASLIQVRDLLALRGRMEAAQISQTLNTPQPMINAMLQQLESMG
                     KAVRIQEEPDGCLSGSCKSCPEGKACLREWWALR"
     gene            44490..45368
                     /gene="rpnA"
                     /locus_tag="RHX21_000576"
     CDS             44490..45368
                     /gene="rpnA"
                     /locus_tag="RHX21_000576"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-promoting nuclease RpnA"
                     /protein_id="HDV1985814.1"
                     /translation="MSKKQSSTPHDALFKLFLRQPDTARDFLAFHLPAPIHALCDMKT
                     LKLESSSFIDDDLRESYSDVLWSVKTEQGPGYIYCLIEHQSTSNKLIAFRMMRYAIAA
                     MQNHLDAGYKTLPMVVLLLFYHGIESPYPYSLCWLDCFADPKLARQLYASAFPLIDVT
                     VMPDDEIMQHRRMALLELIQKHIRQRDLMGLVEQMACLLSSGYANDRQIKGLFNYILQ
                     TGDAVRFNDFIDGVAERSPKHKESLMTIAERLRQEGEQSKALHIAKIMLESGVPLTDI
                     MRFTGVSEEELAAASQ"
     gene            complement(45397..46167)
                     /gene="bioH"
                     /locus_tag="RHX21_000577"
     CDS             complement(45397..46167)
                     /gene="bioH"
                     /locus_tag="RHX21_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709189.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pimeloyl-ACP methyl ester esterase BioH"
                     /protein_id="HDV1985815.1"
                     /translation="MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHL
                     VDLPGFGRSRGFGALSLADMAEAVLQQAPDKAIWLGWSLGGLVASQIALTHPERVQAL
                     VTVASSPCFSARDEWPGIKPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARA
                     LKKTVLALPMPEVDVLNGGLEILKTVDLRQPLQNVPMPFLRLYGYLDGLVPRKVVPML
                     DKLWPHSESYIFAKAAHAPFISHPVEFCHLLVALKQRV"
     gene            46205..46888
                     /gene="gntX"
                     /locus_tag="RHX21_000578"
     CDS             46205..46888
                     /gene="gntX"
                     /locus_tag="RHX21_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417872.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein GntX"
                     /protein_id="HDV1985816.1"
                     /translation="MLTVPGLCWLCRMPLALGHWGICSVCSRATRTDKTLCPQCGLPA
                     THSHLPCGRCLQKPPPWQRLVTVADYAPPLSLLIHQLKFSRRSEIASALSRLLLLEVL
                     HARRTTGLQLPDRIISVPLWQRRHWRRGFNQSDLLCQPLSRWLHCQWDSEAVTRTRAT
                     ATQHFLSARLRKRNLKNAFRLELPVQGRHMVIVDDVVTTGSTVAEIAQLLLRNGAATV
                     QVWCLCRTL"
     gene            46947..47522
                     /gene="nfuA"
                     /locus_tag="RHX21_000579"
     CDS             46947..47522
                     /gene="nfuA"
                     /locus_tag="RHX21_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016942932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S biogenesis protein NfuA"
                     /protein_id="HDV1985817.1"
                     /translation="MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYC
                     PPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVA
                     DDAPLMERVEYMLQSQINPQLAGHGGRVSLMEITEDGYAILQFGGGCNGCSMVDVTLK
                     EGIEKQLLNEFPELKGVRDLTEHQRGEHSYY"
     gene            47883..49199
                     /gene="gntT"
                     /locus_tag="RHX21_000580"
     CDS             47883..49199
                     /gene="gntT"
                     /locus_tag="RHX21_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate transporter"
                     /protein_id="HDV1985818.1"
                     /translation="MPLVIVAIGVILLLLLMIRFKMNGFIALVLVALAVGLMQGMPLD
                     KVIGSIKAGVGGTLGSLALIMGFGAMLGKMLADCGGAQRIATTLIAKFGKKHIQWAVV
                     LTGFTVGFALFYEVGFVLMLPLVFTIAASANIPLLYVGVPMAAALSVTHGFLPPHPGP
                     TAIATIFNADMGKTLLYGTILAIPTVILAGPVYARVLKGIDKPIPEGLYSAKTFSEEE
                     MPSFGVSVWTSLVPVVLMAMRAIAEMILPKGHAFLPVAEFLGDPVMATLIAVLIAMFT
                     FGLNRGRSMDQINDTLVSSIKIIAMMLLIIGGGGAFKQVLVDSGVDKYIASMMHETNI
                     SPLLMAWSIAAVLRIALGSATVAAITAGGIAAPLIATTGVSPELMVIAVGSGSVIFSH
                     VNDPGFWLFKEYFNLTIGETIKSWSMLETIISVCGLVGCLLLNMVI"
     gene            complement(49244..51328)
                     /gene="malQ"
                     /locus_tag="RHX21_000581"
     CDS             complement(49244..51328)
                     /gene="malQ"
                     /locus_tag="RHX21_000581"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HDV1985819.1"
                     /translation="MESKRLDNAALAAGISPNYINAHGKPQSISAETKRRLLDAMHQR
                     TATKVAVTPVPNVMVYTSGKKMPMVVEGSGEYSWLLTTEEGTQYKGHVTGGKAFNLPT
                     KLPEGYHTLTLTQDDQRAHCRVIVAPKRCYEPQALLNKQKLWGACVQLYTLRSEKNWG
                     IGDFGDLKAMLVDVAKRGGSFIGLNPIHALYPANPESASPYSPSSRRWLNVIYIDVNA
                     VEDFHLSEEAQAWWQLPTTQQTLQQARDADWVDYSTVTALKMTALRMAWKGFAQRDDE
                     QMTAFRQFVAEQGDSLFWQAAFDALHAQQVKEDEMRWGWPAWPEMYQNVDSPEVRQFC
                     EEHRNDVDFYLWLQWLAYSQFAACWEISQGYEMPIGLYRDLAVGVAEGGAETWCDREL
                     YCLKASVGAPPDILGPLGQNWGLPPMDPHIITARAYEPFIELLRANMQNCGALRIDHV
                     MSMLRLWWIPYGETADQGAYVHYPVDDLLSILALESKRHRCMVIGEDLGTVPVEIVGK
                     LRSSGVYSYKVLYFENDHEKTFRAPKAYPEQSMAVAATHDLPTLRGYWESGDLTLGKT
                     LGLYPDEVVLRGLYQDRELAKQGLLDALHKYGCLPKRAGHKASLMSMTPTLNRGLQRY
                     IADSNSALLGLQPEDWLDMAEPVNIPGTSYQYKNWRRKLSATLETMFADDGVNKLLKD
                     LDRRRRAAAKKK"
     gene            complement(51338..53731)
                     /gene="malP"
                     /locus_tag="RHX21_000582"
     CDS             complement(51338..53731)
                     /gene="malP"
                     /locus_tag="RHX21_000582"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin phosphorylase"
                     /protein_id="HDV1985820.1"
                     /translation="MSQPIFNDKQFQEALSRQWQRYGLNSAAEMTPRQWWLAVSEALA
                     EMLRAQPFAKPVANQRHVNYISMEFLIGRLTGNNLLNLGWYQDVQDSLKAYDINLTDL
                     LEEEIDPALGNGGLGRLAACFLDSMATVGQSATGYGLNYQYGLFRQSFVDGKQVEAPD
                     DWHRSNYPWFRHNEALDVQVGIGGKVTKDGRWEPEFTITGQAWDLPVVGYRNGVAQPL
                     RLWQATHAHPFDLTKFNDGDFLRAEQQGINAEKLTKVLYPNDNHTAGKKLRLMQQYFQ
                     CACSVADILRRHHLAGRKLHELADYEVIQLNDTHPTIAIPELLRVLIDEHQMSWDDAW
                     AITSKTFAYTNHTLMPEALERWDVKLVKGLLPRHMQIINEINTRFKTLVEKTWPGDEK
                     VWAKLAVVHDKQVHMANLCVVGGFAVNGVAALHSDLVVKDLFPEYHQLWPNKFHNVTN
                     GITPRRWIKQCNPALAALLDKSLQKEWANDLDQLINLEKFADDAKFRQQYREIKQANK
                     VRLAEFVKVRTGIEINPQAIFDIQIKRLHEYKRQHLNLLHILALYKEIRENPQADRVP
                     RVFLFGAKAAPGYYLAKNIIFAINKVADVINNDPLVGDKLKVVFLPDYCVSAAEKLIP
                     AADISEQISTAGKEASGTGNMKLALNGALTVGTLDGANVEIAEKVGEENIFIFGHTVE
                     QVKAILAKGYDPVKWRKKDKVLDAVLKELESGKYSDGDKHAFDQMLHSIGKQGGDPYL
                     VMADFAAYVEAQKQVDVLYRDQEAWTRAAILNTARCGMFSSDRSIRDYQARIWQAKR"
     gene            54343..57048
                     /gene="malT"
                     /locus_tag="RHX21_000583"
     CDS             54343..57048
                     /gene="malT"
                     /locus_tag="RHX21_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MalT"
                     /protein_id="HDV1985821.1"
                     /translation="MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYG
                     KTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIAAVQQATNGHCAICETMAQKRQY
                     ASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSR
                     NLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICHDVSGW
                     ATALQLIALSARQNTHSAHKSARRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAI
                     LRSMNDALITRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCYHPLFGNFLRQRCQW
                     ELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSL
                     LEESLKALPWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREGTMHAE
                     FNALRAQVAINDGNPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSL
                     ALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQL
                     PMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGD
                     LDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEFA
                     NNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQ
                     AGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRI
                     LREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQI
                     AGELEVAATTIKTHIRNLYQKLGVAHRQAAVQHAQKLLKMMGYGV"
     gene            complement(57091..58107)
                     /gene="rtcA"
                     /locus_tag="RHX21_000584"
     CDS             complement(57091..58107)
                     /gene="rtcA"
                     /locus_tag="RHX21_000584"
                     /EC_number="6.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 3'-terminal phosphate cyclase"
                     /protein_id="HDV1985822.1"
                     /translation="MKRMIALDGAQGEGGGQILRSALSLSMITGQPFTITSIRAGRAK
                     PGLLRQHLTAVKAAAEICRATVEGAELGSQRLVFRPGTVRGGEYRFAIGSAGSCTLVL
                     QTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKIGIHQQTTLLRHGFY
                     PAGGGVVATEVSPVASFNTLQLGERGNIVQMRGEVLLAGVPRHVAEREIATLAGSFSL
                     HEQNIHNLPRDQGPGNTVSLEVESENITERFFVVGEKRVSAEVVAAQLVKEVKRYLAS
                     PAAVGEYLADQLVLPMALAGAGEFKVAHPSCHLLTNIAVVERFLPVRFGLIETDGVTR
                     VSIE"
     gene            complement(58111..59337)
                     /gene="rtcB"
                     /locus_tag="RHX21_000585"
     CDS             complement(58111..59337)
                     /gene="rtcB"
                     /locus_tag="RHX21_000585"
                     /EC_number="6.5.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-splicing ligase RtcB"
                     /protein_id="HDV1985823.1"
                     /translation="MNYELLTTENAPVKMWTKGVPVEADARQQLINTAKMPFIFKHIA
                     VMPDVHLGKGSTIGSVIPTKGAIIPAAVGVDIGCGMNALRTALTAEDLPENLAELRQA
                     IEMAVPHGRTTGRCKRDKGAWENPPVNVDAKWAELEAGYQWLTQKYPRFLNTNNYKHL
                     GTLGTGNHFIEICLDESDQVWIMLHSGSRGIGNAIGTYFIDLAQKEMQDQLETLPSRD
                     LAYFMEGTEYFDDYLRAVAWAQLFASLNRDAMMENVVTALQSITQKTVRQPQTLAMEE
                     INCHHNYVQKEQHFGEEIYVTRKGAVSARAGQYGIIPGSMGAKSFIVRGLGNEESFCS
                     CSHGAGRVMSRTKAKKLFSVEDQIRATAHVECRKDAEVIDEIPMAYKDIDAVMAAQSD
                     LVEVIYTLRQVVCVKG"
     gene            59526..61124
                     /gene="rtcR"
                     /locus_tag="RHX21_000586"
     CDS             59526..61124
                     /gene="rtcR"
                     /locus_tag="RHX21_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator RtcR"
                     /protein_id="HDV1985824.1"
                     /translation="MRKTVAFGFVGTVLDYAGRGSQRWSKWRPTLCLCQQESLVIDRL
                     ELLHDTRSRSLFETLKRDIASVSPETEVVGVEIELHNPWDFEEVYACLHDFARGYEFQ
                     PEKEDYLIHITTGTHVAQICWFLLAEARYLPARLIQSSPPRKKEQPRGAGEVTIIDLD
                     LSRYNAIASRFAEERQQTLDFLKSGIATRNPHFNRMIEQIEKVAIKSRAPILLNGPTG
                     AGKSFLARRIFELKQARHQFSGAFVEVNCATLRGDTAMSTLFGHVKGAFTGARESREG
                     LLRSANGGMLFLDEIGELGADEQAMLLKAIEEKTFYPFGSDRQVSSDFQLIAGTVRDL
                     RQLVAEGKFREDLYARINLWTFTLPGLRQRQEDIEPNLDYEVERHATLTGDSVRFNTE
                     ARRAWLAFATSPQATWRGNFRELSASVTRMATFATSGRITLDVVEDEINRLRYNWQES
                     RPSALTALLGAEAENIDLFDRLQLEHVIALCRQAKSLSAAGRLLFDVSRQGKASVNDA
                     DRLRKYLARFGLTWEAVQDQHSSS"
     gene            complement(61106..61864)
                     /locus_tag="RHX21_000587"
     CDS             complement(61106..61864)
                     /locus_tag="RHX21_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family transcriptional regulator"
                     /protein_id="HDV1985825.1"
                     /translation="MKQTQRHNGIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNELA
                     EQNLILRHHGGAALPSSSVNTPWHDRKATQTEEKERIARKVAEQIPNGSTLFIDIGTT
                     PEAVAHALLNHSNLRIVTNNLNVANTLMVKEDFRIILAGGELRSRDGGIIGEATLDFI
                     SQFRLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVN
                     MGSISMVDAVYTDAPPPVSVMQVLTDHHIQLELC"
     gene            complement(61881..62711)
                     /gene="glpG"
                     /locus_tag="RHX21_000588"
     CDS             complement(61881..62711)
                     /gene="glpG"
                     /locus_tag="RHX21_000588"
                     /EC_number="3.4.21.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease
                     GlpG"
                     /protein_id="HDV1985826.1"
                     /translation="MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESQ
                     AERVRAELARFLENPADPRYLAASWQAGHTGSGLHYRRYPFFAALRERAGPVTWVVMI
                     ACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWY
                     LGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERD
                     PQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
                     "
     gene            complement(62756..63082)
                     /gene="glpE"
                     /locus_tag="RHX21_000589"
     CDS             complement(62756..63082)
                     /gene="glpE"
                     /locus_tag="RHX21_000589"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase GlpE"
                     /protein_id="HDV1985827.1"
                     /translation="MDQFECINVADAHQKLQEKEAVLVDIRDPQSFAMGHAVQAFHLT
                     NDTLGAFMRDNDFDTPVMVMCYHGNSSKGAAQYLLQQGYDVVYSIDGGFEAWQRQFPA
                     EVAYGA"
     gene            63272..64777
                     /gene="glpD"
                     /locus_tag="RHX21_000590"
     CDS             63272..64777
                     /gene="glpD"
                     /locus_tag="RHX21_000590"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase"
                     /protein_id="HDV1985828.1"
                     /translation="METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSA
                     SSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIR
                     IGLFMYDHLGKRTSLPGSTGLRFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVV
                     RKGGEVLTRTRATSARRENGLWIVEAEDIDTGKKYIWQARGLVNATGPWVKQFFDDGM
                     HLPSPYGIRLIKGSHIVVPRVHTQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYK
                     GDPKAVKIEESEINYLLKVYNAHFKKQLSRDDIVWTYSGVRPLCDDESDSPQAITRDY
                     TLDIHDENGKAPLLSVFGGKLTTYRKLAEHALEKLTPYYQGIGPAWTKESVLPGGAIE
                     GDRDDYAARLRRRYPFLTESLARHYARTYGSNSELLLGNAGAISDLGEDFGHEFYEAE
                     LKYLVDHEWVRRTDDALWRRTKQGMWLNADQQSRVSQWLVEYTQQKLSLAS"
     gene            complement(64829..65434)
                     /locus_tag="RHX21_000591"
     CDS             complement(64829..65434)
                     /locus_tag="RHX21_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000589351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1985829.1"
                     /translation="MIKFRLYIPPVILGFVIVPLLVWPTVIVLAVLIFTLTFLAEIIF
                     SFPLLVVRISLQELQLELMVEYALFFSVMAGIGWQFSRRTPPELKNRLHCWLVFSPVY
                     FWLILSNFILYISPEKSALLENIRNFFLTFVWPPLNFSPFWPQPWTDFVGPISAQLGF
                     ALGYYCHWCRKNRNQRKKWGNWVTCLSLAILAQGPLFNYLQ"
     gene            complement(65437..66204)
                     /locus_tag="RHX21_000592"
     CDS             complement(65437..66204)
                     /locus_tag="RHX21_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001182130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1985830.1"
                     /translation="MQPSPAMQALIEQIYHIFRRYPVPQKFVVCCEYCLSQQEQKVLR
                     STSLRAISYSLINAWNSSPGPDPQNSDEVRYFLPRLLEFVAQGQFDNIHEVFSLRRIN
                     LASKENWREDEWKILQRFACQYMTDWVSGDEAVELQYMLEMFFRADIALAPLLDAINS
                     VPGFWSTVSLACLLNRYCEDYIRDNQDDIDNVITTQINAWARNNHPLLKERARQAIEN
                     PLKQPEPMTEYQVWEDDWIIDECLCAMYDASSESPGK"
     gene            complement(66207..66917)
                     /locus_tag="RHX21_000593"
     CDS             complement(66207..66917)
                     /locus_tag="RHX21_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1985831.1"
                     /translation="MELVNTLFASLVGTDPFTGVDITIANCKSAYWDEGIVQQLINQA
                     LDEGEKFVGADGLEGLLRYNVTLNIGLTSSKVWPGFSLDTATISRLCACGADFGFDPY
                     ISDVPDVQCDLNTTNDVTVQFTAMLNPDERVIIAKRPLKKCDSWIEDVYIFQVLKDAW
                     KFHNNNSLRGFRDKQAELKLYTRHYSVENCAEESCRDCNSCIRPSFSLSRSALIRLNA
                     ANARFVYQPFTRDQRARG"
     gene            complement(66932..68440)
                     /locus_tag="RHX21_000594"
     CDS             complement(66932..68440)
                     /locus_tag="RHX21_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312299.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PstS family phosphate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDV1985832.1"
                     /translation="MMQNRKWILTSLVMTFFGIPILAQFLAAVIAMLGVGLAGIIEVC
                     NIFITPTIYLLLNIFMLALGALMLFFSGRVWADDSAPEKREIAVWRQCLFLVPALLTL
                     GVWIIALHLADYQFRQMGAGWLADLMLPWLGVLLASLVGGEYWWLVIIPVGAHISFSL
                     GYGWPTRYPLTGTSGLRCRNSLLFILLMLGFVAGYQAYLYKQLNPGVGVRENIDTWAW
                     RPDKLNNQLTPLRGKPQIQFTQNWPRLDGATAAYPIYASAFYALSVLPEDFHEWEYLA
                     NSRTPEAYNKIVKGNADIIFVAQPSGGQKKRAEESGVTLIYTPFAREAFVFIVNVDNP
                     VNSLTEQQVRDIFSGAITNWRTVGGNDQEIQTWQRPEDSGSQTVMQSQVMKNVRMISP
                     QETEVASMMEGMIKVVAEYRNTNNAIGYTFRYYATQMNADKNIKLLAINGIAPTAENI
                     RNGKYPYIVDAFMVTRENMTSETQKLVEWFLTPQGQSLVEDVGYVPMYKTLH"
     gene            complement(68565..71012)
                     /gene="glgP"
                     /locus_tag="RHX21_000595"
     CDS             complement(68565..71012)
                     /gene="glgP"
                     /locus_tag="RHX21_000595"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen phosphorylase"
                     /protein_id="HDV1985833.1"
                     /translation="MNAPFTYSSPTLSVEALKHSIAYKLMFTIGKDPVVANKHEWLNA
                     TLFAVRDRLVERWLRSNRAQLSQETRQVYYLSMEFLIGRTLSNAMLSLGIYEDVQGAL
                     EAMGLNLEELIDEENDPGLGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNI
                     VNGSQKESPDYWLEYGNPWEFKRHNTRYKVRFGGRIQQEGKKTRWIETEEILGVAYDQ
                     IIPGYDTDATNTLRLWSAQASSEINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTY
                     SGRELRLRQEYFLVSSTIQDILSRHYQLHKTYDNLADKIAIHLNDTHPVLSIPEMMRL
                     LIDEHQFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGKILPRHLQIIFEINDYF
                     LKTLQEQYPNDTDLLGRASIIDESNGRRVRMAWLAVVVSHKVNGVSELHSNLMVQSLF
                     ADFAKIFPGRFTNVTNGVTPRRWLAVANPSLSAVLDEHLGRNWRTDLSLLNELQQHCD
                     FPMVNHAVHQAKLENKKRLAEYIAQQLNVVVNPKALFDVQIKRIHEYKRQLMNVLHVI
                     TRYNRIKADPDAKWVPRVNIFGGKAASAYYMAKHIIHLINDVAKVINNDPQIGDKLKV
                     VFIPNYSVSLAQLIIPAADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEML
                     DHVGADNIFIFGNTAEEVEELRRQGYKPREYYEKDEELHQVLTQIGSGVFSPEDPGRY
                     RDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYELQEEWTAKAMLNIANMGYFSSDR
                     TIKEYADHIWHIDPVRL"
     gene            complement(71031..72464)
                     /gene="glgA"
                     /locus_tag="RHX21_000596"
     CDS             complement(71031..72464)
                     /gene="glgA"
                     /locus_tag="RHX21_000596"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HDV1985834.1"
                     /translation="MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDARVLLPAF
                     PDIRRGVTDAQVVSRRDTFAGHITLLFGHYNGVGIYLIDAPHLYDRPGSPYHDTNLFA
                     YTDNVLRFALLGWVGAEMASGLDPFWRPDVVHAHDWHAGLAPAYLAARGRPAKSVFTV
                     HNLAYQGMFYAHHMNDIQLPWSFFNIHGLEFNGQISFLKAGLYYADHITAVSPTYARE
                     ITEPQFAYGMEGLLQQRHREGRLSGVLNGVDEKIWSPETDLLLASRYTRDTLEDKAEN
                     KRQLQIAMGLKVDDKVPLFAVVSRLTSQKGLDLVLEALPGLLEQGGQLALLGAGDPVL
                     QEGFLAAAAEYPGQVGVQIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTL
                     PLVRRTGGLADTVSDCSLENLADGVASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRF
                     VQRQAMAMDFSWQVAAKSYRELYYRLK"
     gene            complement(72464..73759)
                     /gene="glgC"
                     /locus_tag="RHX21_000597"
     CDS             complement(72464..73759)
                     /gene="glgC"
                     /locus_tag="RHX21_000597"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HDV1985835.1"
                     /translation="MVSLEKNDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPA
                     VHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLL
                     PAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKG
                     ARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVF
                     DADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRD
                     VGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLV
                     SGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPE
                     GMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER"
     gene            complement(73777..75750)
                     /gene="glgX"
                     /locus_tag="RHX21_000598"
     CDS             complement(73777..75750)
                     /gene="glgX"
                     /locus_tag="RHX21_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen debranching protein GlgX"
                     /protein_id="HDV1985836.1"
                     /translation="MTQLAIGKPAPLGAHYDGQGVNFTLFSAHAERVELCVFDANGQE
                     HRYDLPGHSGDIWHGYLPDARPGLRYGYRVHGPWQPAEGHRFNPAKLLIDPCARQIEG
                     EFKDNPLLHAGHNEPDYRDNAAIAPKCVVVVDHYDWEDDAPPRTPWGSTIIYEAHVKG
                     LTYLHPEIPVEIRGTYKALGHPVMINYLKQLGITALELLPVAQFASEPRLQRMGLSNY
                     WGYNPVAMFALHPAYACSPETALDEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPL
                     FSLRGIDNRSYYWIREDGDYHNWTGCGNTLNLSHPAVVDYASACLRYWVETCHVDGFR
                     FDLAAVMGRTPEFRQDAPLFTAIQNCPVLSQVKLIAEPWDIAPGGYQVGNFPPLFAEW
                     NDHFRDAARRFWLHYDLPLGAFAGRFAASSDVFKRNGRLPSAAINLVTAHDGFTLRDC
                     VCFNHKHNEANGEENRDGTNNNYSNNHGKEGLGGSLDLVERRRDSIHALLTTLLLSQG
                     TPMLLAGDEHGHSQHGNNNAYCQDNQLTWLDWSQASSGLTAFTAALIHLRKRIPALVE
                     NRWWEEGDGNVRWLNRYAQPLSTDEWQNGPKQLQILLSDRFLIAINATLEVTEIVLPA
                     GEWHAIPPFAGEDNPVITAVWQGPAHGLCVFQR"
     gene            complement(75747..77933)
                     /gene="glgB"
                     /locus_tag="RHX21_000599"
     CDS             complement(75747..77933)
                     /gene="glgB"
                     /locus_tag="RHX21_000599"
                     /EC_number="2.4.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching enzyme"
                     /protein_id="HDV1985837.1"
                     /translation="MSDRIDRDVINALIAGHFADPFSVLGMHKTTAGLEVRALLPDAT
                     DVWVIEPKTGRKLAKLECLDSRGFFSGVIPRRKNFFRYQLAVVWHGQQNLIDDPYRFG
                     PLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARRVSVVGQFNYWD
                     GRRHPMRLRKESGIWELFIPGAHNGQLYKYEMIDANGNLRLKSDPYAFEAQMRPETAS
                     LICGLPEKVVQTEERKKANQFDAPISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYA
                     KWMGFTHLELLPINEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFIDAAHAAGLNVIL
                     DWVPGHFPTDDFALAEFDGTNLYEHSDPREGYHQDWNTLIYNYGRREVSNFLVGNALY
                     WIERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRILGEQV
                     SGAVTMAEESTDFPGVSRPQDMGGLGFWYKWNLGWMHDTLDYMKLDPVYRQYHHDKLT
                     FGILYNYTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWMWAFPGKKLL
                     FMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNLTYRHHKAMHELDFDPY
                     GFEWLVVDDKERSVLIFVRRDKEGNEIIVASNFTPVPRHDYRFGINQPGKWREILNTD
                     SMHYHGSNAGNGGTVHSDEIASHGRQHSLSLTLPPLATIWLVREAE"
     gene            complement(78206..79309)
                     /gene="asd"
                     /locus_tag="RHX21_000600"
     CDS             complement(78206..79309)
                     /gene="asd"
                     /locus_tag="RHX21_000600"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HDV1985838.1"
                     /translation="MKNVGFIGWRGMVGSVLMQRMVEERDFDAIRPVFFSTSQLGQAA
                     PSFGGTTGTLQDAFDLEALKALDIIVTCQGGDYTNEIYPKLRESGWQGYWIDAASSLR
                     MKDDAIIILDPVNQDVITDGLNNGIRTFVGGNCTVSLMLMSLGGLFANDLVDWVSVAT
                     YQAASGGGARHMRELLTQMGHLYGHVADELATPSSAILDIERKVTTLTRSGELPVDNF
                     GVPLAGSLIPWIDKQLDNGQSREEWKGQAETNKILNTSSVIPVDGLCVRVGALRCHSQ
                     AFTIKLKKDVSIPTVEELLAAHNPWAKVVPNDREITMRELTPAAVTGTLTTPVGRLRK
                     LNMGPEFLSAFTVGDQLLWGAAEPLRRMLRQLA"
     gene            79502..80095
                     /gene="yhgN"
                     /locus_tag="RHX21_000601"
     CDS             79502..80095
                     /gene="yhgN"
                     /locus_tag="RHX21_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter YhgN"
                     /protein_id="HDV1985839.1"
                     /translation="MNEIISAAVLLILIMDPLGNLPIFMSVLKHTEPKRRRAIMVREL
                     LIALLVMLVFLFAGEKILAFLSLRAETVSISGGIILFLIAIKMIFPSASGNSSGLPAG
                     EEPFIVPLAIPLVAGPTILATLMLLSHQYPNQMGHLVIALLLAWGGTFVILLQSSLFL
                     RLLGEKGVNALERLMGLILVMMATQMFLDGIRMWMKG"
     gene            complement(80152..81492)
                     /gene="gntU"
                     /locus_tag="RHX21_000602"
     CDS             complement(80152..81492)
                     /gene="gntU"
                     /locus_tag="RHX21_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate transporter"
                     /protein_id="HDV1985840.1"
                     /translation="MTTLTLVLTAVGSVLLLLFLVMKARMHAFLALMVVSMGAGLFSG
                     MPLDKIAATMEKGMGGTLGFLAVVVALGAMFGKILHETGAVDQIAVKMLKSFGHSRAH
                     YAIGLAGLVCALPLFFEVAIVLLISVAFSMARHTGTNLVKLVIPLFAGVAAAAAFLVP
                     GPAPMLLASQMNADFGWMILIGLCAAIPGMIIAGPLWGNFISRYVELHIPDDISEPHL
                     GEGKMPSFGFSLSLILLPLVLVGLKTIAARFVPEGSTAYEWFEFIGHPFTAILVACLV
                     AIYGLAMRQGMPKDKVMEICGHALQPAGIILLVIGAGGVFKQVLVDSGVGPALGEALT
                     GMGLPIAITCFVLAAAVRIIQGSATVACLTAVGLVMPVIEQLNYSGAQMAALSICIAG
                     GSIVVSHVNDAGFWLFGKFTGATEAETLKTWTMMETILGTVGAIVGMIAFQLLS"
     gene            complement(81496..82023)
                     /gene="gntK"
                     /locus_tag="RHX21_000603"
     CDS             complement(81496..82023)
                     /gene="gntK"
                     /locus_tag="RHX21_000603"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HDV1985841.1"
                     /translation="MSTTNHDHHIYVLMGVSGSGKSAVASEVAHQLHAAFLDGDFLHP
                     RRNIEKMASGEPLNDDDRKPWLQALNDAAFAMQRTNKVSLIVCSALKKHYRDLLREGN
                     PNLSFIYLKGDFDVIESRLKARKGHFFKTQMLVTQFETLQEPGADETDVLVVDIDQPL
                     EGVVASTIEVIKKGK"
     gene            complement(82162..83157)
                     /gene="gntR"
                     /locus_tag="RHX21_000604"
     CDS             complement(82162..83157)
                     /gene="gntR"
                     /locus_tag="RHX21_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001693277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate operon transcriptional repressor GntR"
                     /protein_id="HDV1985842.1"
                     /translation="MKKKRPVLQDVADRVGVTKMTVSRFLRNPEQVSVALRGKIAAAL
                     DELGYIPNRAPDILSNATSRAIGVLLPSLTNQVFAEVLRGIESVTDAHGYQTMLAHYG
                     YKPEMEQERLESMLSWNIDGLILTERTHTPRTLKMIEVAGIPVVELMDSQSPCLDIAV
                     GFDNFEAARQMTTAIIARGHRHIAYLGARLDERTIIKQKGYEQAMLDAGLVPYSVMVE
                     QSSSYSSGIELIRQARREYPQLDGVFCTNDDLAVGAAFECQRLGLKVPDDMAIAGFHG
                     HDIGQVMEPRLASVLTPRERMGSIGAERLLARIRGESVTPKMLDLGFTLSPGGSI"
     gene            complement(83381..84076)
                     /gene="yhhW"
                     /locus_tag="RHX21_000605"
     CDS             complement(83381..84076)
                     /gene="yhhW"
                     /locus_tag="RHX21_000605"
                     /EC_number="1.13.11.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004213399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quercetin 2,3-dioxygenase"
                     /protein_id="HDV1985843.1"
                     /translation="MIYLRKANERGHANHGWLDSWHTFSFANYYDPNFMGFSALRVIN
                     DDVIEAGQGFGTHPHKDMEILTYVLEGTVEHQDSMGNKEQVPAGEFQIMSAGTGIRHS
                     EYNPSSTERLHLYQIWIMPEENGITPRYEQRRFDAVQGKQLVLSPDARDGSLKVHQDM
                     ELYRWALLKDEQSVHQIAAERRVWIQVVKGNVTINGVKASTSDGLAIWDEQAISIHAD
                     SDSEVLLFDLPPV"
     gene            complement(84199..85236)
                     /locus_tag="RHX21_000606"
     CDS             complement(84199..85236)
                     /locus_tag="RHX21_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDV1985844.1"
                     /translation="MVINCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQ
                     APIYSHIHFTSDLDEVLNDPDVKLVVVCTHADSHFEYAKRALEAGKNVLVEKPFTPTL
                     AQAKELFALAKSKGLTVTPYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVA
                     ETKPGLPQDGAFYGLGVHTMDQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFYGD
                     LKAIVKTSHLVKIDYPKFIVHGKKGSFIKYGIDQQETSLKANIMPGEPGFAADDSVGV
                     LEYVNDEGVTVREEMKPEMGDYGRVYDALYQTITHGAPNYVKESEVLTNLEILERGFE
                     QASPSTVTLAK"
     gene            85569..86057
                     /gene="yhhY"
                     /locus_tag="RHX21_000607"
     CDS             85569..86057
                     /gene="yhhY"
                     /locus_tag="RHX21_000607"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDV1985845.1"
                     /translation="MSEIVIRHAETRDYEAIRQIHAQPEVYCNTLQVPHPSDHMWQER
                     LADRPGIKQLVACIDGDVVGHLTIDVQQRPRRSHVADFGICVDSRWKNRGVASALMRE
                     MIEMCDNWLRVDRIELTVFVDNAPAIKVYKKYGFEIEGTGKKYALRNGEYVDAYYMAR
                     VK"
BASE COUNT        20790 a        23489 c        21633 g        20213 t
ORIGIN      
        1 tttattaaag ttgcactggt aggtgcggta ctggctacgt taactgcatg tactggtcat
       61 attgaaaacc gtgataagaa ctgctcttac gactacctgc tgcacccggc aatttctatt
      121 tctaaaatca ttggcggttg cggtcctact gcacagtaag tctctgacag aaatcggcta
      181 acaccggttt aattgcccga cgccctctgg attttccgag ggcgtatttg tttctatgtc
      241 cttcttgccc ccgcccgtaa aaatattttc actttaaatt caatttgata aatacatcca
      301 ttagccacag cgcgatcctg tgcgaaattt tgtgatcttc ctccacatta cataacatca
      361 tatgttgtta tattcatcat gcattgtcat gttacctttt aaatgactgc aaactctccc
      421 ctacaacgta ttggacaaga aaaaggtatc gctatgggaa gccaggaact ccaacgcaag
      481 ctcggatttt gggccgttct tgcaatcgcc gtcgggacaa ccgtcggctc cggtattttt
      541 gtatctgtgg gtgaagtggc aaaagcagcg ggcacgccgt ggcttacggt gctcgcgttt
      601 gtcattggcg ggttaattgt gatcccgcaa atgtgcgtct atgcggaact atccaccgct
      661 tatccggaaa atggcgcaga ttatgtttat ctgaaaaatg ccggaagccg accgctggct
      721 ttcctctccg gctgggccag cttctgggcc aacgatgcgc cgtcattgtc gattatggcg
      781 ctggcgattg tcagcaatct tggcttttta acgcctatcg atccgttgct cggtaaattt
      841 atcgccgccg gattaattat cgcctttatg ttgctacacc tgcgctccgt tgaaggcggc
      901 gcagcgtttc agacgctaat taccatcgcc aaaattatcc cgttcactat cgtcattggc
      961 cttgggatct tctggtttaa agcggagaat tttgccgccc ctaccaccac tgcgattggc
     1021 gcaacgggca gctttatggc gctgctggcg gggatctctg ccaccagttg gtcgtatacc
     1081 ggcatggcct ctatctgtta tatgaccggc gaaattaaaa accccggaaa aaccatgcca
     1141 cgagcgctga ttggttcctg tctgctggtt ctggtgctct acaccctgct ggcgctggtg
     1201 atttccggcc tgatgccctt cgacaaactc gccaattctg aaacgccgat ttccgacgcc
     1261 ctgacctgga tccccgcact cggcagcacc gctgggatct ttgttgccat cacggcgatg
     1321 atcgtcattc ttggttcgct ttccagctgc gtgatgtacc agccgcggct ggaatacgcg
     1381 atggcgaaag acaacctgtt ctttaaatgc ttcggccatg tgcatccgaa atacaacacg
     1441 ccggatgtct ccatcatcct gcaaggggcg ctggggatct tcttcatctt cgtttccgat
     1501 ctcaccagcc tgctgggtta tttcaccctg gtgatgtgtt tcaaaaatac cctcaccttc
     1561 ggctccatca tctggtgtcg taaacgcgac gattacaaac cgctgtggcg tactccggct
     1621 ttcgggctga tgaccaccct cgccattgcg tcaagcctca ttctggtcgc ctcaaccttt
     1681 gtctgggcac cgattcccgg ccttatctgc gccgtcatcg ttattgctac tggtctgcct
     1741 gcttacgcct tctgggcgaa gcgtagccgc cagctcaacg ctttgtcgta atgttatctg
     1801 gagaaaataa aatgttggat attgataaaa gcaccgtgga ctttctggtc accgaaaata
     1861 tggttcagga agtggaaaaa gttctcagcc atgacgttcc gctggtgcac accatcgtgg
     1921 aagagatggt gaagcgcgac attgatcgta tttatttcgt tgcctgcgga tcgccactca
     1981 acgcggcgca aacggcgaaa catctggcgg atcgcttttc cgatcttcag gtctacgcca
     2041 tttccggctg ggagttctgc gataacaccc cgtatcgcct cgacgatcgt tgcgcggtga
     2101 ttggcgtttc tgactacggt aaaacggaag aggtaatcaa agcgctggag ctgggccggg
     2161 cctgcggcgc actcactgcg gcgttcacca aacgcgcgga cagcccgatt acctcggcgg
     2221 cggaatttag cattgattat caggccgact gtatctggga aattcacctg ctgctctgct
     2281 acagcgtggt gctggagatg atcacccgcc tcgcgccgaa cgcggaaatc ggcaagatca
     2341 aaaacgatct caagcaattg ccgaatgcgc tcggtcatct ggtacgcacc tgggaagaaa
     2401 aaggccgcca gcttggtgaa ctggccagcc agtggccgat gatttatacc gttgctgcgg
     2461 gtccgctgcg tccgctgggt tacaaagaag gcattgtaac gctgatggaa tttacctgga
     2521 cgcacggctg cgtgattgag agcggagagt tccgccatgg cccgctggag attgtcgaac
     2581 cgggcgttcc gttcctgttc ctgctcggca atgatgaaag tcgccacacc accgaacgcg
     2641 ccattaactt tgttaaacag cgtactgaca acgtgatcgt catcgattac gccgaaattt
     2701 cgcaagggct gcacccgtgg ctggcaccgt tcctgatgtt cgtgccaatg gagtggctct
     2761 gctactacct gtctatttac aaagatcaca acccggatga acgccgctat tacggtggtc
     2821 tggtggaata ttaatccctc tcccggcccg gcaacgggcc gaatttacgc aaggagttac
     2881 ccgatgaaaa caggtatgtt tacctgcggc caccagcggc tgcctattga acacgcattt
     2941 cgtgatgcaa gcgagctggg ttacgacggc atcgaaattt ggggcggtcg cccgcacgcg
     3001 ttcgcgccgg acttaaaagc gggcggcatc aaacaaatca aggcgctggc gcagacgtat
     3061 cagatgccga ttatcggcta tacgccagaa accaacggct atccgtataa catgatgctg
     3121 ggcgatgaac atatgcgtcg cgaaagcctc gacatgatca agctggcgat ggatatggca
     3181 aaagagatga acgcgggtta tacgctgatt tccgcggccc acgcgggcta tctcacgcca
     3241 cctaatgtta tctggggacg gctggcagag aacctaagcg aactgtgtga gtacgcggaa
     3301 aacatcggca tggatctaat cctcgaaccg ttaacgccgt atgaatcgaa cgtcgtgtgt
     3361 aatgctaatg atgtgcttca tgcgctggcg ctggtgcctt cgccgcgcct gttcagcatg
     3421 gtcgacattt gcgcgccgta tgtccaggcg gaaccggtga tgagttattt cgacaaactg
     3481 ggcgataaat tacgtcatct gcatattgtc gacagcgacg gggccagcga cacgcattac
     3541 attcctggag aaggcaaaat gccgctgagg gaactgatgc gcgatattat cgaccggggc
     3601 tatgagggtt actgtacggt ggagctggtg acgatgtata tgaacgagcc cagactctat
     3661 gcccgccagg cgctggaacg ctttcgcgcg ctgctgccgg aggatgagag atgaaaaccc
     3721 tggcgacaat cggcgataac tgcgtcgata tctacccgca actgaataaa gcgttttctg
     3781 gcggtaatgc ggtcaatgtg gcggtgtact gcactcgcta cggcatacag ccgggatgca
     3841 ttacctgggt gggtgacgat gactacggca caaagctgaa gcaggatctc gcccgcatgg
     3901 gcgtcgatat cagccatgtc catacgaaac acggcgttac cgcacaaact caggtggaac
     3961 tgcacgacaa tgatcgcgtt tttggcgact acaccgaagg cgtgatggcc gactttgccc
     4021 tgagtgaaga ggattacgcc tggctggcgc agtatgacat tgtgcacgcg gcaatctggg
     4081 gacatgcgga agacgcattc ccacagctgc acgctgcggg caaacttacc gctttcgact
     4141 tctccgacaa gtgggacagc tcgctctggc agacactggt gccgcatctc gattttgcct
     4201 ttgcctccgc accgcaagaa gacgaagcgc tgcgtctgaa gatgaaagcg attgttgccc
     4261 gtggcgcagg cgtggtgatt gtcacgctgg gtgaaaacgg cagcattgcc tgggatggcg
     4321 cgcagttctg gcgtcaggct cctgaaccgg tgacggttat cgacaccatg ggtgccggag
     4381 attcgttcat tgccggattc ctttgcggct ggtctgcggg gatgacatta ccgcaggcga
     4441 tggcgcaggg aacggcgtgc gcggcgaaaa ccattcagta ccacggtgcc tggtaggtat
     4501 aacgttggcg tgagcatctt cacgccaacg tgctgttact tgccggaaaa cgaccctata
     4561 atccgagtaa ttcattcttt atttcagggt cgattatgtc agctacggac cgctactctc
     4621 atcaactcct ctacgctacc gtccgccagc ggttgctgga tgatatcgcg cagggggttt
     4681 accaggccgg gcaacagatc cctaccgaaa acgagctttg tacgcaatat aacgtcagcc
     4741 gcattactat tcgcaaagct atcagcgact tagtggcaga cggcgtactg atccgctggc
     4801 agggcaaagg cacctttgta caaagccaga aggtcgaaaa cgccctgctg accgtcagtg
     4861 gttttaccga ttttggcgtc tcacaaggca aggcgacgaa agagaaagtg atcgagcagg
     4921 aacgagtcag cgccgcgccg ttttgcgaaa agctgaacat ccctggcaac agcgaagtgt
     4981 tccatctttg ccgggtgatg tatctcgata aagagccgct gtttattgat agttcctgga
     5041 tcccactgtc gcgttatcct gactttgatg agatttacgt tgaaggaagc tccacttatc
     5101 agttatttca ggagcgtttc gacacgcgag tggtcagcga caaaaagacc atcgatatct
     5161 ttgccgccac ccgcccgcag gcaaaatggc tgaaatgcga actgggcgaa ccgttgtttc
     5221 gcatcagcaa aatcgccttt gatcagaatg acaaaccggt gcacgtctcc gaactcttct
     5281 gccgcgccaa tcgcatcacc ttaacgattg ataataaaag acattaaccg taggccggat
     5341 aagatgcgcc agcatcgcat ccggcgatgc tggcgcgttg aattttacat cccgtacgtt
     5401 cccctcaccc taaccctctc cccaaagggg cgaggggacc gttcagtacg gaatttagct
     5461 tgacggtgct atccagcatt aaatactggc aatactctca cgcaaaatcc gcagcaccgt
     5521 ctcttcaccg ctgcgattcg ggttaatgcg aatcgcacaa tgttctgatt gtggattcgc
     5581 ctggcgaaac gttccggaaa ggcgataaaa gagcggcggg atttcatatt tcgactctgc
     5641 acccaccggg taaggcaagg caccgcgctt ttgcgcctct tccagcactc tggcggcaat
     5701 cggctgatga aactcgacaa tcaacacctt cgactgcgca ttagcaatca ccgcgctttt
     5761 cacttccggc accgcaccac cgttaagcaa agccagcaac cgttcagata cccctgcctg
     5821 caccgcgtgc atcactggcg caaacaccag accacgcaat acttccagcg cctgtgcgcc
     5881 ctggatctgg ctaccgccgg agtaaagcgt ggcgcgaata cggttgataa catcagcatc
     5941 gccgaccact gcaccaacac cctctggccc aaatagcttg aagcaggaaa atgtcgagac
     6001 attcgcgccg cattcacagc cgattcgcgc caccttcatc accgcatagt tgtcatcggt
     6061 taacgctgga acacctgccg cgcgcaacgt tgccagcaca tctgccagca cgtagctgtc
     6121 ctgcggctgc tggcgcgtat gctgcaccag cgccgcatcc ggttgttgct cgtcgacgac
     6181 ctgcttcagt gccgacaggt cattgaaatc aacagtaata agcgtcagcc ccatctgctc
     6241 aataataacc cgtgtcgtcg ggtaaacagg cgcgtcatgc accagaagac gctgccccgg
     6301 tttgagcaaa gccgccagcc cggcgcgaat cgcgccagtc cccgcgccct gcaccagcgc
     6361 cgcagcctgt gcgtgaaatg catcagccag cacctgttcc acacgctggg taacgcgcgg
     6421 ttgattcagt cctggcgtta agcctaaatc accgccagta agaaactcgc tgccggggaa
     6481 atggcgacaa atgctatcca ccagcgcaaa ctgcttttgc tgcgcctcaa taatcgtcag
     6541 gctttgcaga ggaaacgtct tcataggtgc cttccttaag ccggaacgaa caggccaagc
     6601 cagtaaagaa cattcagcag aataccggtg atcattactg ccacgaccgg tgccgccatt
     6661 ttctgtaccg gacggcccag ggattcgttg aggaagtaaa tggcaaccgc gatagagaat
     6721 ccggtataac ccgccatctt aattgctgcg aaaatcgaac cgaccagcag cgccacttcc
     6781 atcagcatat tcatggcgtt acggatgtta tccgacgcat tacgcaccga cggatagcgc
     6841 cccagccatt tgccgatcga acgaagcaat aaaacttctg ccgaaataac cactgcacct
     6901 aataccgctg caaccatcgg attcggcgag agatagccca ccgcataaac aaaggtaaag
     6961 cccgcaactg catacacacc cgttgctaac gcggtggtgg caatcaacgg cacaaacccc
     7021 agtccgcgca taaattctgc cagagccgcc tgattaatca gcgtttgcga ttgttccggc
     7081 gttacgcctg cggaatatgc tttctccagt gtgaagatcg acacttcact gccagcaaaa
     7141 atcttcatgc tggcaacggc ggcaatcaat gctcccacga tggcgatata gggtaagttt
     7201 ttgataatcc gtgacgtgcg ttcttcaaac accgaaagcc cgctggcatc aatgtcattt
     7261 tcatcacgat gacgcaggtc gtgagttatc gcgatcccca gcagcatcac catgccaata
     7321 aagatttcga tggattcagg gttaagatgt gggaaatagc gcacgactac cacacgggtc
     7381 atcagtacca ccacggcggc gatcagactt tgcttccagc caaactggta gaaaatcgcc
     7441 accagcggga acagtgcaaa agctgaaacc accggcgagc ttaattcccc caggctacct
     7501 aatacatcca ccggcagcgc ggtcagcagc tggtttactg gcaacaggca agtaaggatc
     7561 aacacgcccc agatagcgcc aagaccaaac gccatcaggc tgtttatcgc caggacgccg
     7621 aggatatcgg taggaagaaa gagtaaccat gcgttgagca gcccggtttt cagggtaaaa
     7681 gagatcccca ccgaggccac aaaaccaatg ctcagaccaa aagcgatact ccccgcctcg
     7741 cgacggttca tatagccttc aatcagttgc ggcaggatcg ggcggatgcc gtcatgaaaa
     7801 acagccgccg agcgatgcgc cagaagcgat gtcatacccg tcaggcacgc caccacgata
     7861 atctgaatat acagatccat agtcgtgcct tttatttcag atggttaatc agcatcggaa
     7921 tcgcgtgttc gacgtgctca acggaaaggc caaacgccac tttcccttcg gcgatcattt
     7981 tggcgatatg ctcgtctttc gctttaatgc ctggtttggc aatggtgcaa cttttgttat
     8041 agccaatcac cgcgatggca atcgacaatg ccgcgcccgc accggtatta cacgcaccga
     8101 tgtagtaatc cagttgcccg gatttcactt tcattgccgc ttccatgtcg ttgtgaatga
     8161 aaacttcaaa actgccagga gccgtcgctt caatggtttt tttaatctgc tcacgctgta
     8221 agcctgcaac gccaatcttt ttcatgagtc tgtccttatt ggaaaaattg agagggattt
     8281 tcacgtaaca tcacatccac atcggcctga ctgaatcctg actggcgcaa ttgcggaata
     8341 aaggtggtca ataaatagtc atagccataa ccaccattgg cttttaaatg ggagcggcgc
     8401 gtaatatccg tcgacagcat gacgcggttc agcaacccac ggtcacgtag cgcgtggagc
     8461 atcgcaatgc gcttttcgtc cgggtagtaa ctgttcttac caatggtgtc gaactgcacg
     8521 tacgcgccga gatcgatcat cttcaaaatg ttgtcgagat tgtctttcag atcgcagtga
     8581 ccaacggtga cgcgcgaaag atcaactccg tgggcttgca acagagccag ttgttccagc
     8641 cccatggtgc tgaacgaagt atgcgtggag atcgggcgtc cggtctggtt atgcgccagc
     8701 gcagcggcaa taaacacctt ctcttccagc ggcgtaatct tcccttcgct agagccgatc
     8761 tccgcgataa tcccggcttt caggtcggtg ccatcgatac cctgttcaat ttcatcgacc
     8821 atctcctgcg ccagttcctg cacgctgcgg gtcgccacat gctccgggaa aaaagcgtcc
     8881 tggtaataac cggtgcaggc caccacgttg atccccgtct cgcgcattac atcgagcata
     8941 aattgcgcat tgcgccccat gtaacggttg gtcatctcaa tcacattacg cacgccccgg
     9001 gtcatcaggt cgttcatctc ctggcaaatg aacgcatact gatcaaggcg gcagtccacg
     9061 ttgtttttaa agccggagag atcaatatgc agatgctcat gggccagggt gtaacccgtc
     9121 ggatcaatac tcatagggtg tctcctgcaa accggaggga ggaaagaaaa gagcgaccat
     9181 tttgtggcgg tggcgcacgg aaaaattcac acacggtagc ccccacatca gaaagcgtgg
     9241 tgcgtacacc gagttgcgtg tggaccagcc cttgctgata aaccagcact ggcaccactt
     9301 cacgggtatg gtggctgtga ccaatggtcg gatcgttacc gtgatccgcc atcacgacca
     9361 ggcaatcatc tggctgcatc gcctcaacaa gccgggcaag gttacggtca acgacctgca
     9421 aacgttcggc ataacgtgcg acgtcttctg catgaccagc gaggtcggtt tcctggatat
     9481 tgatgcaaat aaacgccgtc ggatgcgtgt taaattcgtc gagggtgata tccataatcc
     9541 gctggctatc caccagattt tgccagctca cgccataagg attgttgacg atatctgcca
     9601 ccttacccac cagcacggtt ggcacgcctg cttcatacag tttttgtggc acctgcactt
     9661 tttcatcgac gccatagccc atatgcacga cctggaaacc gttgtcataa gcgccagaac
     9721 gcggcgcatt gataccaata aagcgccctt ctttgctttc tgcggcatcg agaaggcgtt
     9781 gactgtcggt taacaggcca ccaaatgtaa tgacccgacc gacctgtacc tgctcacgca
     9841 cgatacgacc aattttgatt gcgtcgtcaa aagagatcac agagagattg gcggtaatgt
     9901 tatagacctg gcctaaatcc gcctcgagat tatcgccaat cgcaaccgcc tgattgaccc
     9961 acagaaattg cagttcatcg ccacggcgct ccacctgcca accggcggat actaatgcct
    10021 gctcaacacg gtcaatcaca tcgcaaaaag gcatccgcag cggcggtaac gggcgcgtgc
    10081 ctaaaatttc ctgatgcccc ataaaggtat cgccaccttc atgttgcagc tctgccacgc
    10141 cccaggttgc ggaatctgac ggctgcatat cgcctggcgc ataacccaat gcgttgatta
    10201 gccccagctt ctccagcgtt ggtagctgca aatgcggcaa ctggctcagg atgtgaccac
    10261 aggtattcgc tcccgcatct tgcggacgca ccagcgtgac atctttcatt gcccctacgc
    10321 caaagctatc aatcactaac accacaaatc gcgccattac gcccccagag agtttccaag
    10381 actgtcataa cgaccaacga ttttcggttc gccacggtga ataccggaca ccagcaccac
    10441 atcgctacgg gtgacaaaaa tctgcgtgcg gaaacagagc accactgcac tgctcaccgg
    10501 atactcgcct gccagcggca gggtgtagtc gatactgctg tcatccacag ttttgagatt
    10561 ggtttcagta atcttttgat tttctggcgt aaacaccagc gcatgttgcg catgaccacg
    10621 acggtagtaa ccgccgccgt agcagtagct gtcgccacgg aaatgatggg agatttcact
    10681 taaccagagc atcgcgatac gttcaggctg atcgccctgc tggtttgccg gaatagtgcc
    10741 cgtcagcgca tgaccgggtt cggcatgagt cacaccgtat tgcgccagca atggcagcga
    10801 agtgcagctg gtcgctgaag gcgcgttcag ttgctcaatc gcaataccag atttcgccag
    10861 ttgatcccgt gcttgtacca gcgtgtgaag attcggtgtc ggcaaaactt tcccggcagc
    10921 ctcatcccaa agcaggcaag ggaaatgggt tagtcccgcc aaatgcagcc ccggcagttt
    10981 cttaatttca gcaaccacct cgtgcagcga atgctgtaca aaaccgctct cctgccccgg
    11041 ataaagaaaa tcatcgtcgc tataaacttt gagcagcaca gactggattc gcccggcctt
    11101 caccgccgcc gcagaaactt cccgcgcttt gtcgagagta aacacggtga tgacgtcggt
    11161 gccctgttca acggcgtcag caacctgatg acaagggatt tgtaccagat gcccctgatg
    11221 cgccaccggc aaaccagcgc ggcgcatgac tcgcgcctct ttgtaatcca ccgccacaat
    11281 gccgctgtag cccaacgcca gcagtttttc cgccagccat gggttacgac cgaattgttt
    11341 ggtcatcaga tacagttcaa tgccgtaaag ccgcgccgtc tcaatcagcc gcttaccgtt
    11401 ttccagtatc tgatccacgt cgatcaccca gctgtccggg gcgattttgc cctgctgcca
    11461 caaacttagt gcggcggaaa tcagcgccgg gttctggcgt ttcaatgctt ctacaaacat
    11521 cttgttgcct cgtttctgtt ccttgaatta aatattcatt tttttgaata tttaggttgt
    11581 gcgacgtgga tttgtcagga gcttcaaacc tcttcgttag cagccatcca taatccataa
    11641 aggttggcca gcaaatagcc ttcttcacac gggttaactt ccagtgcgaa ttccttcaac
    11701 aacacctgat gcaattgcac aacggcttgc cagtggctgg attgcgccag ctctgccagc
    11761 aattcgttat ccagcggctc tatttcttca ccacggcgac tgcgcatcag tgcactcgcc
    11821 atatgtgtca tcgccatcgt tccttgctca ctgcgcaccg gcagatggca ctctgtttcc
    11881 agtacgttga cgacctgcat catgcctttg cagatgtcct tatcaataac gcctgcctcg
    11941 caaagcaggt tgagtctggt ttccatatca gatgcctttc gtttaataac tcggttcctg
    12001 ttccccactc actacccgtt gttgatgggc gagcagggcg tgtttatcta caacggcacg
    12061 cagcagttgt tgcattgggt aatcatcgac tcgcgtcagg accacggctt cggtggcctg
    12121 taaaaatcgc ggatcgtctg tgagcggcgt cgcctctaat cccagcatgg tcagttcgtt
    12181 ttccgccacc acgttccaga tcaccgcatc gacatcgcct ttaacaatgc gttgtaaact
    12241 ctcgtgataa gagagatcga ctcgttccac atcactaccg ccaaaaaaaa catcggtcat
    12301 gattttctga tccgccgaac ggttatccag ccccacgcgc ttcacgtttg cggactcgcc
    12361 tttacggcaa atcaactggt gctcgccaac gtaggtgtgc ggccccaact ccagcgcgag
    12421 gcataaccct ttttgcgtga gataactttc cgccgccagt cgggaaacca ccgccatgtc
    12481 atacacgccg ttaagtaaac actccacgcg aatatccgcg ccgcgcatat gcgcatagta
    12541 aaaaggaatg ccatcaaact gagctttcag cccgctcgct aaaccttcgt acaagcgggt
    12601 atagggcaaa ggcatcgcac ataccacgtt gttgatatcc acatgactca gcaatgcttt
    12661 gttatccatc tcgaccagat aactgccatt gcgcccacgg cgttcaatcc gtatcgctcc
    12721 gcttgattcc agcgttttca acgcggcctg cgtcaggcca accgatgaac ggcattcagt
    12781 tgccagctca tctatggttt tcaacctatt accgcatttt tcacccaaca aataacgggc
    12841 cagcgtcgtg ataacgacgc cttctttttt gataaacgtt cgacgcataa tatattttca
    12901 ataaaatgaa tgtttatatc ttcattaaaa tgaagataag tggcaactgt gagatgtgga
    12961 aacggcgagg cgcttcacat tttttcggat tattgcaaat gaggataaaa aaaccgggtt
    13021 tccccggttt cagagtgatg acgaagtgat ttattcgaca atgcgagcaa agggtaattc
    13081 ccactggcgc ttgcctgctc ccctcaccct aaccctctcc ccaaaggggc gaggggaccg
    13141 tccgagcgtt ttgatattac ggcttcgcca caaaaccaat cgcttcgtac accgctttca
    13201 gcgtacggga agcgtgtaca ctggcttttt ctgcgccgtc tttcatcacc tgttgcagga
    13261 aggcttcatc gttgcggaaa cgatgatagc gttcctgcaa ttcagtcagc ataccggaaa
    13321 cggcatcagc cacttcacct ttcagatgac catacatctt gccttcgaac tgtttttcca
    13381 gttctgggat gctctggccc gttaccgcag aaaggatatc cagcaggttg gaaacgcccg
    13441 ctttgttctg cacatcgtag cgaactaccg gcggctcgtc ggagtcagtg accgcgcgtt
    13501 tgattttctt cactaccgat ttcggatctt ccagcaggcc gataacgtta ttgcggttat
    13561 cgtcagactt ggacatcttc ttggtcggct ccagcagcga cattacgcgc gcgccagatt
    13621 tcggaataaa cggctccggc accttaaaga tctcgccata cagcgcgttg aaacgctggg
    13681 cgatatcgcg actcagttcc aggtgctgtt tctggtcttc acccaccggt accagattag
    13741 tttgatacag caggatgtcc gcagccatca gcaccggata gtcaaacaga ccagcgttga
    13801 tgttctcggc ataacgcgca gatttatctt taaactgggt catgcggctc agttcgccga
    13861 agtaggtata gcagttcagt gcccagccta actgcgcatg ttctggtacg tgggactgaa
    13921 caaaaatggt gcttttctca ggatcgatac cacaagccag atacaaggcc agcgtatcca
    13981 gcgtcgcttt acgcagcttc tgtgcatcct ggcgcacggt gatcgcgtgt tggtcaacga
    14041 tacagtaaat gcaatggtag tcatcctgca tgtttaccca ctgacgcagc gcacccatgt
    14101 agttaccaat ggtcaattca cctgagggct gtgcgccact aaaaacgatg ggcttagtca
    14161 tttttcgatt cctgattttc gctatgcgga agccctaatg cgggcagaag gtcatttata
    14221 gactgataaa ttacatcagg ctggctgaga tcgatagcct cgccgtagtt atatccgtag
    14281 gttaagccaa cggatgggca acctgccgct tttgccgcct gaatatcatt gcgtgagtcg
    14341 ccgacaaaca gcatctgttg tggggcaatt cccatccgct cagccaccag taacagcggg
    14401 tccggatgag gttttttgtt ttgcacatca tcgccgccga taaccacgct aaagtatttg
    14461 gcaatatcta aggcttcgag cagcggcgcg acgaacggcg tcggtttgtt ggtgaccagg
    14521 cctagcggca ggcctttagc ctgcaacgcg cccaacgtat cggcagcgtg cgggaacaaa
    14581 aacgtcccct cttcggcaac ctcgccatag tagcgatcga acagtttacg cagaatacgt
    14641 acctgttctt ctgccggaat gtcgtcatca acgggcggtt tacccattgt tttacgctga
    14701 gtcgcacgtt cctgacgcgc ccaggtcaat gcgcgctcca tcagaacatc tgcgccgtta
    14761 ccaatccagg taataacgcg ttcttcacct gcgacgggca actccagcgc atacagcgcc
    14821 atatctaccg cagcagcaag accgggagca ctgtcgacca gcgtaccatc aagatcaaaa
    14881 gcgacgccgc gaatatcttc aaacttattc atgacttacc tttgccagtt cactgcgcat
    14941 ttcatcaatg acttttttgt agtctggctg gtcgaagatt gccgaaccgg cgacgaacat
    15001 atccgcgccc gccgcagcga tttcgccaat gttgttcacc ttcacgccac cgtctacttc
    15061 cagacgaatg tcaaagccag actcgtcgat acgacgacgt acttcgcgca gtttatccag
    15121 tgtttgagga atgaacgact gaccgccgaa accaggattg acggacatca gcaggatcac
    15181 atccagctta tccatcacgt aatccagata gctcagcggt gtcgccgggt taaataccag
    15241 tcccgcttta cagccatttt ctttaatcag ttgcagcgtg cggtcaacat gctcggaggc
    15301 ttctggatga aaggtaatga tgctggcacc agcggcagcg aaatcaggca caatgcgatc
    15361 gacaggtttc accatcaggt gtacgtcgat aggggcggta atgccgtagt tacgcaagga
    15421 tttcagcacc attggcccaa tcgtcagatt gggaacatag tggttatcca tgacgtcaaa
    15481 atgcacgaca tcagcgccag ctgccagggc ttttgcggta tcttcaccca ggcgggcaaa
    15541 atcagccgac agaattgagg gggcaatcaa atactgtttc atccgcttct ccttgagaat
    15601 tattttttcg cgggtgaaac gactcctggt ttgtacaaag ccagcagttc gtccaccttt
    15661 ttacgtgtgc cgccgttgct gcttatactg cgtcgaactt tgacgacatg caattttgcg
    15721 cgctgatacc actcacgcgt taacatcgta tcgtgattgg agatcagcac tggaatatgg
    15781 cgctcaacca gaccttcggc gatctccgcc agatgcgctt gttgttcaag cgtaaaactg
    15841 tttgtgtgat acgccgtaaa gttggcggtc gcagacagcg gtgcataagg cggatcgcaa
    15901 tagacgacgg atgcatcatc tgcgcgcgcc atgctatcgg cgtaagactc acaatagaaa
    15961 aaggcattct gcgctttttc agcgaagtga tacaactctg cttccgggaa atagggtttt
    16021 ttgtagcggc caaacggcac gttaaactca ccgcgcagat tgtaacgaca caggccgttg
    16081 taaccgtagc ggttcaaata taaaaacagt accgcccgac ggaacggatc ctggcttttg
    16141 ttgaactctt cgcggaactg atagtagacc tcggcgcaat ttgtttcggg aacaaacagc
    16201 tcgcgtgcgg cctgtacgta ctcatcagta cgcatcttca caatgttata gagactgatc
    16261 aggtcgctat tgatatcggc aaggatataa cgagaaaagt cggtgttgag aaacaccgac
    16321 ccggcaccta caaaaggctc aaccagacat tcgcccttgg gcaaatgccg tttaatatca
    16381 tcaagcaggg gatacttgcc ccctgcccac ttcaaaaaag cgcgattttt cttcatgctg
    16441 actaactaat tacaccttct ccggctgtgg agaaagctcc gacagcatcc agcgcttcag
    16501 gcaactcccg caacgataac ccattgcggg agataacctt gattacttca gatcggcctg
    16561 tacctgacgc agcggtttcg cccacgggtt tttggcctga acatctgctg gcaatgtaga
    16621 taccgctttt ttcgcctctt ctttcgaagc gtacacgcca gaaaccagga cataccacgg
    16681 ctgaccatta cgcgtcgttt catagacaac gtagtttttc agattctctt tcttcgccca
    16741 accgttcagg ttgtcgtagt tagaggaact gctcagctgc agagtgtaat ggctggacgg
    16801 tgccgatttc aacgaaccaa cattacctgc ggtcttccct ccagcggctg gtgttgccgt
    16861 ggtttgcgcc ggggatgccg tctgtactgg agccgtagtc gccgtctctt ttggtgctgg
    16921 cgcagaagtc gcagccggtg ccttcgtgct cgccacagga gcagctggtt cagtacgctt
    16981 cggcgtctgt gctaccggct tcggttccgt tttcacggtt gcttgcggtt ttttcggttc
    17041 aatcaccgcc tgctgacgag ctggacgcgt agtggccgga cgttcagcag tttgcgtttt
    17101 cgccgtgtca cgcgatgcat tgccattgcg tactggcgcg acagttgctg gttcagtcgg
    17161 caatgtagaa ttgaccgcca cattgttcaa ctgttgctga ttttgtggct gggtcagcgc
    17221 attgttcagg tcaccctgca cttcaacacg ttgttgacca tccgttgccg ccggggtttg
    17281 cccttgagtc ggcgtagaag agatcggtgg cagagaaaca tcctgctgag tattttccgc
    17341 agacgtggtt cccggcgctg gctgcacccc attcgcctga tcggtcgcat tgcctgcaag
    17401 atcaatactc ttctcgccag acgcggtttg atcgctggaa gaggtcgagg gggcttttag
    17461 cgcagaaccg ataccgatga tcaacagcag tagaaccaga atgccgacgc ccatcatcat
    17521 atactgacga gaagcgggtt tactggctgc ttttttgcgc ttacgcggac gacgctctac
    17581 gcgctcttca tccacggttt catcttcgga ttcgtcaatt tcttcttcga tttccggttc
    17641 ctcattgcgc tctttttgcg cacgagtcgg acggcgatcg tcagtgtcat caagttcaat
    17701 atcatcaaaa ttgatctgcg gttcgccacg ttcagtacgc tcagaacgtt cagaagattg
    17761 acgagaacga ccagtacgac gatcgctggg atcgggtttc agctcgtctt ctggtttgaa
    17821 ttcatccatt taacacccca ctaaaaggtt aatgcttacc acgttgcaat taacctgaag
    17881 ctaatagacc gcttgataag cggcctgacc tttcttgttg ttacgctgat tgacaatcgg
    17941 caatggcgtt aagaacaagc tcgtgcgaaa cgccgctgcg aacttcactc ttaccaattg
    18001 ccaacggaag aattaagcgt atctctcccg caaggacttt cttgtcacgc agcatatgcg
    18061 gtaaatacgc ctgcgcggac atttcgcgcg gcccattgac cggtaaccca gcccgcttga
    18121 gcagggttat aatacgctgc gtttcggcag aactaaactg cccgagacgt tccgacgtcc
    18181 gcgccgccat caccataccc gcagcgaccg cttcaccatg taaccaattg ccatacccca
    18241 tttcagcttc aatggcatga ccaaaggtgt gtcccagatt cagtaaagca cgtaacccgg
    18301 tttcgcgctc gtcggcggcg acaacttctg ccttcagttc acaacaacgg cgaatacagt
    18361 acgccattgc cggaccgtcc agacgcaaca acgcatccag attctcttcc agccagttaa
    18421 aaaacgcacc gtcaagaata atgccgtatt tgatgacttc tgccagcccc gacgctaact
    18481 cacgcggggg aagcgttttc agacagtcga gatccaccac cactgaagca ggctggtaga
    18541 acgcgccaat catgttttta ccgaggggat ggttgaccgc agttttgccg ccaacggagg
    18601 aatcgacctg cgacagtaac gtcgtcggga cttgaatgaa acgaacaccg cgctgataac
    18661 tcgccgccgc gaagccggtc agatcgccca ctacgccgcc gccaagcgcc accagcgtag
    18721 tatcgcgacc atgcggcttt tgtaacaacg ccgtaaagac ggtatcgagt acagccaggc
    18781 ttttatactg ctcgccgtca gggaggataa cgctatcgac gttaacaccc gcctgttcaa
    18841 gtacgccgcg gaccttatcg agatacagag gagccagggt ttcgttggtg accaacatga
    18901 cctgctcgcc cgatttcagc ggtaagaatg aagctggttc attaaacaaa ccagatgcga
    18961 tggtaattgg gtaactacgt tccccgagag taacgacaat cctctccata acgcgacatc
    19021 caccttaatt actgtacccg cagacgagtg tatataaagc cagaattagt tgctttccag
    19081 catgtgaata atctggtttg caaccacttt agcgctttga tcatcagtac gaatggtcac
    19141 gtcggcaatc tcttcataca gcggattgcg ttcattggcc aacgcttcca gaacttcacg
    19201 cggcggtgtt tcaacgtgca gcaacgggcg ttttttatca cgctgcgtgc gtgcaagttg
    19261 cttttcgatg gtcgtttcaa gataaacgac aacgccacga gcggaaagac ggttacgcgt
    19321 ttcacgggat ttcacagagc cgccgccagt agccagcaca ataccctgtt tctcggtcaa
    19381 ctcattgatg accttttctt cgcgatcgcg gaagccttct tcgccttcta aatcgaaaac
    19441 ccagcccaca tcagctccgg ttcgtttctc aatctcttga tcggaatcgt aaaattccat
    19501 attgagttgt tgagctaact ggcgcccaat agtgcttttt ccggcaccca taggcccaac
    19561 cagaaagata ttgcgtttct ctgccatttt ttcggtacta ctaagactat tcgttaatga
    19621 taaacccgct tcgctcagag agcgccgcag gacatgaact gaaacctcat aagatattgc
    19681 gagagtcaga ctgaaaatta tctcaatact ccagcgggtt tggcaactga ataaatcacc
    19741 catccctctg catatctggt cgctgcaagc gcgctgcctt gctaccaccg ctctggcgat
    19801 aaatcaccgg gtaagattag cgtaaaaaag acagcaaaat gccgcctgaa tgataaatca
    19861 tcatcatgga acgcaggcag cgaagagcac caactctcaa atcggtactc cttgtatgct
    19921 aaatacctgc gcgcgtcaaa tagatgaaac acgttcagca taaaaacatt accgctttta
    19981 cggctgttta ctcactggaa accagtcgtg gcgtgataaa caccactaac tcgcgtcgtt
    20041 catcttcttt tccgtcatga cgaaataatt gcccgaacca gggaatgtcg ccaagcaacg
    20101 gtacgctatc ctgacccgat ttatttttac gggtaaaaat gccgcccagc gccaacgttt
    20161 ctccgctttt gacctcgacc tgcgtttcga tctcctgctt atcaatcgcc agcacttcgc
    20221 catcggcctg ctgtagcacc tgccccggaa cgttctggct gatgtgtaat ttcagccgga
    20281 tgcgaccttt ttgtaacacc gtgggcgtga cctccatccc caggacggcc tctttaaatt
    20341 ccaccgacgt cgcgccactt tccccgctgg aaacctgata tggaatttcg ctcccctgtt
    20401 taatgctggc aggctgaaga tgtgaggcca gcagacgcgg actggcgata atatccagct
    20461 gctgtttttg ttcgagcgcg gaaagctcaa gatccagcaa gcgtccgttg atgcgcccaa
    20521 tgttaaaacc gacatgcgtt gtcgccgtcg ctacggagag gtcgctacca agcgtggtga
    20581 cttgcccaac accaccagcg tgttgcgcat cggccagcgt ccatttcacg cctaactcac
    20641 gcaaactttt ttcattaatg gtgacaatat gcgccgacag ctcaacctgc ccgaccggaa
    20701 gatccatttg cgctacccac tgttcaagcg cgcttaacgc cgttttgtta tctcgtagca
    20761 aaaggcgatt ggtgcgttta tcgacggtca tactcccttt ggcactcagt agcttctccc
    20821 ccgctttcgc cagttctccc gcgtcggcgt attgcagggt tatactgcga ttttccagcg
    20881 gcagatttgc ctgcgcccgc gcctgctccg cctcctggcg ggcgatattg tcattctgcc
    20941 aggcaataga atgcactgag agaatgttgc cctcctggcg cgttatcagc ccggcgcttt
    21001 tcactacagt ttgtagtgcc tgcttccagg gaacatctgt tagatgtaac gacaccgtac
    21061 cgctgacgtc tggcgacacg accaggttca acttctcctg ttcagccagc gcctgcaaca
    21121 cctgagccac cggaacgtca tccaccatca gcgtcacttt ttgcggcttt gccgcctgta
    21181 cgccgggtat cagcatcaac agtagtgcgg ctatccattg cttcatttgt atctccttgc
    21241 cgttgccaca accattgtgg cggttcgcag tttgtcccgg tacccagcgt tagtacgtct
    21301 ggcgtcagct gtaaaattgt ccagccgttt tccagcacat cgttttgctg cacccgtcgc
    21361 catttctttt gcccgtcttt tattacaccg atgatgcgct cgcctcgccc taccatcccc
    21421 tgatagcgcc actggctaag ttcgctaatc cggcatagat cttccggcgg tttaaaaggg
    21481 tcacgcatac cggttaaaag gcacaatgca atacctgcca acaaccagcg tttaaccctc
    21541 atgcggcgtc tccagttgta gcgtgaacaa aagatcatca ccttccacgc ttaacgaaaa
    21601 acggctcacg ctgacgttgc gctctgccag ccgtgtaaat gccgacggca ctgcttccca
    21661 cagcgttttc aacgccaact cgcctccctg cgcggatgga tgccaggaaa ccagttgcgc
    21721 gccggataac tgaaaatcca gtggcgaaaa gggcagcgtt ttttcctcgc tgaagggagt
    21781 ggtgtctacc aggcgataca gtgcggccca ctgctggtga tgacttgccc gtagtcgaat
    21841 taatgcgtcg cgctcttcat ggtgtgtcga tgatagaaaa atgagcgtaa ctaacatcag
    21901 caaccagaat gcccagcaaa gctggcggag gcggggtgat gtggcgaacc accagtcaaa
    21961 gaacatgttc atcgctaacc ttccttgtta actgatactc aaattgccag cgtccctgcg
    22021 catcctgctg cgtggctccc cgctgattga gatgaaaaga cgcatcctgg cggagtgacg
    22081 tttctagtgc gtttaacgcg gtaatgcttg ttgtcagccc cttgatctcc agcgttccct
    22141 gctgccagct tatcgttgtc agccaggcgt gctcgggtaa aagcgccgcc agtgcttcca
    22201 gcgcagattg ccagtcgcgg gtaaattgtc gctggcgctg ccgttgcgaa cgctgttcgc
    22261 gtaactgctg ttgctccagc aaacgtggct tcgttatctg taagctgcgg gcgagttgtt
    22321 gttccgcctg aagcaaaact gcgtctatgc gcgcttcggc gctgcctgtc agacgcagta
    22381 ttagcgttat cccgacggcc agcagcagag gcgcaacgaa catcagcaac cagaaacgca
    22441 gaaaagcggt ccggcgttgc tgtcgccagg gcaaaaaatt aattggcggg ttcatcagta
    22501 cgccttccca agcgccagcc ccagcgcgat ggcaaagtct ccacctggcg gcggtagcgg
    22561 cggctgacga acagaaacgg cctcccaggg atcaaatccc ccttcgccac atatcgcgac
    22621 gctttcggga tcaacggata acgctgccgc cagctccttc gcgctagtca tccccaccgc
    22681 cagtttgcgc ccccagcgac agcgtgtcgc ccacagccac tgttcgttat cacgccaggc
    22741 cagacattgc tgatgagaag gtaaaaaagg caggaattgc tgtaatgcac tggcatccgg
    22801 ggtgatcgcg ctcacatgaa cacgcaacct ttctgccaga gtaagtagcg ttgccagctc
    22861 tttgctttgc gcggcagtca cgttataggc ggggctgagt gagtcttcgc tgtaatcgaa
    22921 gcgcagggag tccggatcca tatccagctc gcgggccatc gtccctgaca gccaggccgt
    22981 ttgctcccgc tcaccaaggg acatcgacgg gcgcggaaat gaccgctgta atgtgcgact
    23041 ggcgggaaac gccaacataa tgtgatgacg ctgcggcagt tcgcgactcc acggtaacaa
    23101 cgttttagcc agctgctgcg catcaacaat ccgcccatct ttgataatgt cgttctccag
    23161 cggcaaccgc caccagcgtt gcaaaaagca ttcttttgct ccccgcacga tcgcaaccgc
    23221 taccgcttct tgctgttgta aatgcaaacc aatttgccag atcttaaatg ccattgtgat
    23281 gatctcctta tcacccgtca ctctgacggg tatatcaatg cgtctggctt gcctttatac
    23341 taccgcgcgt ttgtttataa actgcccaaa tgaaactaaa tgggaaattt ccagtgaagt
    23401 tcgtaaagta ttttttgatc cttgcagtct gttgcattct gctgggagca ggctcgattt
    23461 atggcctata ccgctacatc gagccacaac tgccggatgt ggcgacatta aaagatgttc
    23521 gcctgcaaat tccgatgcag atttacagcg ccgatggcga gctgattgct caatacggtg
    23581 agaaacgtcg tattccggtt acgttggatc aaatcccacc ggagatggtg aaagccttta
    23641 tcgcgacgga agacagccgc ttctacgagc atcacggcgt tgacccggtg gggatcttcc
    23701 gtgcggcaag tgtggcgctg ttctccggcc acgcgtcaca aggggcgagt accattaccc
    23761 agcagctggc gagaaatttc ttcctcagtc cagaacgcac gctgatgcgt aagattaagg
    23821 aagtcttcct cgcgattcgc attgaacagt tgctgacgaa agacgagatc ctcgagcttt
    23881 atctgaacaa gatttacctc ggttaccgcg cctatggtgt cggtgctgcg gcacaagtct
    23941 atttcggtaa aacggtcgac caactgacgc tgaacgaaat ggctgtgatc gccgggctgc
    24001 cgaaagcgcc ttccaccttt aatccgctct actcaatgga tcgtgccgtc gcgcggcgta
    24061 acgtcgtact gtcgcggatg ctggatgaag ggtatatcac ccaacaacag ttcgatcaga
    24121 cacgcactga ggcgattaac gctaactatc acgcgccgga gattgctttc tctgcgccgt
    24181 acctgagcga aatggtgcgc caggagatgt ataaccgtta tggcgaaagt gcctatgaag
    24241 acggttatcg catttacacc accatcaccc gcaaagtgca gcaggccgca cagcaggcgg
    24301 tacgtaataa cgtgctggac tacgacatgc gccacggcta tcgcggcccg gcaaatgtgc
    24361 tgtggaaagt gggcgagtcg gcgtgggata acaacaagat taccgatacg ctgaaggcgc
    24421 tgccaaccta tggtccgctg ctgcctgccg cagtcaccag cgccaatcct cagcaagcga
    24481 cggcgatgct ggcggacggg tcgaccgtcg cattgagtat ggaaggcgtt cgctgggcgc
    24541 gtccttaccg ttcggatact cagcaaggac cgacgccgcg taaagtgacc gatgttctgc
    24601 aaacgggtca gcaaatctgg gttcgtcagg ttggcgatgc atggtggctg gcacaagtgc
    24661 cggaagtgaa ctcggcgctg gtgtcgatca atccgcaaaa cggtgccgtt atggcgctgg
    24721 tcggtggctt tgatttcaat cagagcaagt ttaaccgcgc cacccaggca ctgcgtcagg
    24781 tgggttccaa catcaaaccg ttcctctaca ccgcggcgat ggataaaggt ctgacgctgg
    24841 caagtatgtt gaacgatgtg ccaatttctc gctgggatgc aggtgccggt tctgactggc
    24901 agccgaagaa ctcaccaccg cagtatgctg gtccaattcg cttacgtcag gggctgggtc
    24961 agtcgaaaaa cgtggtgatg gtacgcgcaa tgcgggcgat gggcgtcgac tacgctgcag
    25021 aatatctgca acgcttcggc ttcccggcgc aaaacattgt ccacaccgaa tcgctggcgc
    25081 tgggttcagc gtccttcacc ccaatgcagg tggcgcgcgg ctacgcggtc atggcgaacg
    25141 gtggcttcct ggtggacccg tggtttatca gcaaaattga aaacgatcag ggcggcgtga
    25201 ttttcgaagc gaaaccgaaa gtagcctgcc cggaatgcga tattccagtg atttacggtg
    25261 atacgcagaa atcgaacgtg ctggaaaata acgatgttga agatgtcgct atctcccgcg
    25321 agcagcagaa tgtttctgta ccaatgccgc agctggagca ggcaaatcag gcgttagtgg
    25381 cgaagactgg cgcgcaggag tacgcaccgc acgtcatcaa cactccgctg gcattcctga
    25441 ttaagagtgc tttgaacacc aatatctttg gtgagccagg ctggcagggt accggctggc
    25501 gtgcaggtcg tgatttgcag cgtcgcgata tcggcgggaa aaccggtacc actaacagtt
    25561 cgaaagatgc gtggttctcg ggttacggtc cgggcgttgt gacctcggtc tggattggct
    25621 ttgatgatca ccgtcgtaat ctcggtcata caacggcttc cggagcgatt aaagatcaga
    25681 tatcaggtta cgaaggcggt gccaagagcg cccagcctgc atgggacgct tatatgaaag
    25741 ccgttcttga aggtgtgccg gagcagccgc tgacgccgcc gccaggtatt gtgacggtga
    25801 aaatcgatcg cagcaccggg cagttagcta atggtggcaa cagccgcgaa gagtatttca
    25861 tcgaaggtac gcagccgaca caacaagcgg tgcacgaggt gggtacgacc attatcgata
    25921 atggcgaagc acaggaattg ttctgattaa aaaggcgctt cggcgccttt ttcagtttgc
    25981 tgacaaagtg cactttgttt ataccggata cggcgtgaac actttacccg tctagcaaca
    26041 tctagaaaaa tcaatatatt gcagaaactt cgtaagcctg ataagcatta tgcatcaggc
    26101 gaactttacg catttacact cgcccctgcc ctttcaacca ttcacgcacg aggaacagcg
    26161 cgctgacatt acgcgcttcg ttgaagtcag ggtcttccag caaatccatc atatgcgcca
    26221 gcggccagcg cacctgtggt agcggctctg gctcatcgcc ttccagcgat tccgggtaga
    26281 gatcttgcgc taccacgata ttcattttgc tggaaaaata agacggtgcc atgctgagct
    26341 tcttcaaaaa agtcagatcg ttcgcaccaa atccaacctc ttcttttagc tcgcggttag
    26401 cggcttcgta gacgctttca cccggatcaa ttaaaccttt cgaaaaacct aattcgtagg
    26461 attcagttcc cactgcgtat tcgcggatca ggatcaggtg atcgtccaca atcggcacaa
    26521 tcatcactgc ttcccggttg gttggacgca ttcgttcata aacacgccgc acgccattgc
    26581 tgaactccag atccacgctc tcgacggtaa acagtcggga acgggctaca gtttcaacat
    26641 tcagaatggt gggtttttgt aatgatttgc tcatcgtggg atctatgctg tgaaatcagc
    26701 ggttattgtg cgatatcgga cacgctttcg gcaatgtgaa ttgcatgtta tttacattta
    26761 tgtaacttaa taaataatcg tcctcaaatc aaattaaaag tcaataggtt gaaataactc
    26821 caggaatttg ctgatattcc gccttcagag ggtttgctat gatcagcggt tactgtgatg
    26881 tgcttaatga tgctcaagtt aaactccacg cttgccgata gccaaccgca gaatcatgta
    26941 ttgtgtctgg tgcgactgac cacgcctgac agactaagta agatggggaa agcatgagca
    27001 ccattgtgat ttttttagct gctttgctgg cctgctcact acttgcggga tggctgataa
    27061 aagtgcgatc cagacggcgt cagctgccct ggaccaacgc cttcgcggat gcgcaaacgc
    27121 gtaaactcac acctgaagaa cgtagcgccg ttgaaaatta tcttgagagc ctgacgcagg
    27181 tattacaggt gcctggccca acgggagcta gcgcggcacc gatctctctg gcgctgaatg
    27241 ccgaaagcaa caacgtcatg atgctgacac acgctatcac gcgttacggc atctctaccg
    27301 acgatccgaa taaatggcgt tactacctcg attcggtaga agtccacctg ccccctttct
    27361 gggaacaata catcaacgat gagaataccg ttgaactgat ttataccgat tcgctgccgc
    27421 tggttatttc actcaacggt catacgctgc aggagtacat gcaggaaacg cgcggctatg
    27481 ccttgcaacc tgttccgtcc acgcaggcgt cgattcgcgg ggaagagagt gagcaaatcg
    27541 agctactcaa tattcgcaaa gaaacgcatg aagaatatgc gctgagtcgt ccgcgcgggc
    27601 tgcgtgaagc gttgctgatc gtcgcctcct tcctgatgtt ctttttctgc ctgattaccc
    27661 cggatgtatt tgttccgtgg ctggcaggcg gcgcattact gctgctgggc gcaggtctgt
    27721 gggggctatt cgcgcccccg gcaaaatcct ccctgcgaga aattcattgt ctgcgcggta
    27781 caccccgtcg ttggggattg tttggcgaaa acgatcagga acagatcaac aatatttcac
    27841 tcggtattat cgacctggtc tatcccgcac actggcagcc atacattgct caggatctcg
    27901 gtcaacaaac cgatattgat atctatctcg accgccacgt agtgcgtcag gggcgatatc
    27961 tttcgctgca tgatgaagta aaaaactttc cgttacagca ctggctgcgc agtacgatta
    28021 tcgctgcggg ctcgctgctg gtgctgttta tgctgttatt ctggatcccg ctggatatac
    28081 cgctgaaatt cactctctca tggatgaaag gcgcgcagac cattgaagcc accagcgtaa
    28141 aacaactggc tgacgctggc gtgcgggtag gcgatacatt gcgtattagc ggtacgggaa
    28201 tgtgtaatat tcgcacttcc ggaacctgga gcgcgaaaac caattcacct tttttaccgt
    28261 ttgactgctc gcagatcatc tggaatgacg cccgctcatt accattacca gaatctgaac
    28321 tggtcaacaa agcgacggca ttgactgaag cagttaatcg ccagctgcac cctaaaccgg
    28381 aagatgaatc tcgcgtcagt gcctcattac gttcagcgat tcaaaaatcc ggcatggtat
    28441 tgcttgatga ttttggcgac attgtactga agacagcgga tttatgttct gccaaagatg
    28501 actgtgtgcg actgaaaaat gcgctggtca atctcggcaa cagtaaagac tgggacgcgc
    28561 tggtaaaacg cgccaacgcc gggaagctcg atggcgtgaa tgtgttatta cgcccggtga
    28621 gtgcggaatc gctggataac ctggtggcaa cctccaccgc gccgtttatc acgcatgaaa
    28681 cggcgcgagc ggcacaatca ctaaacagtc cggcccccgg cggattcctg attgtcagcg
    28741 acgaaggcag cgattttgtt gatcagccct ggccttcggc atcactttac gactacccgc
    28801 cgcaagaaca gtggaacgct ttccagaaac tggcacaaat gctgatgcat acgccgttta
    28861 acgccgaagg tatcgtcaca aaaatcttca ctgacgccaa tggtacgcag catattggcc
    28921 ttcatccgat cccggatcgt tccggcctgt ggcgctatct cagcaccaca ttgctgctac
    28981 tgacgatgct gggtagcgcc atttacaatg gcgtacaggc ctggcgtcgt taccagcgtc
    29041 atcgcactcg catgatggag attcaggcct attatgaaag ctgcctgaac ccgcaactga
    29101 tcaccccttc agaaagcctt atcgaataac acgtttgcgc ggcaggttat gctaccctgt
    29161 cgcgcaaatt gcttcactct ggagatttcc ctcatgcata tcaacattgc ctggcaggac
    29221 gtagataccg ttctgctgga tatggacggc acattgctcg acctcgcctt cgataactat
    29281 ttctggcaaa agctggtgcc tgaaacatgg ggcgcgaaaa acggggttac gccacaggaa
    29341 gcgatggaat atatgcgcca gcaatatcac gacgtacagc atacgctaaa ctggtactgt
    29401 cttgattact ggagtgagca actgggtctg gatatctgtg cgatgaccac cgagatggga
    29461 ccgcgtgccg tactgcgtga agataccatt ccgtttcttg aggcactgaa agccagcggt
    29521 aagcagcgaa ttttgctcac caatgcgcat ccgcacaacc tggcggtaaa acttgagcat
    29581 accggtctgg acgcacacct tgatttatta ctttccaccc acacatttgg ttatccgaaa
    29641 gaggatcagc ggttatggca tgcggtggcc gaagctacgg gtctgaaagc tgaaagaacg
    29701 ctgtttattg atgacagcga agcgattctc gatgctgccg cgcaatttgg tattcgttac
    29761 tgcctcggcg tgactaatcc tgattccggg attgccgaga aacagtatca acgccatccg
    29821 tcactgaatg actaccgccg cctgatcccc tcgctaatgt gaaggagacg ccatgaaaga
    29881 aaaacctgct gttgaggttc gactggataa atggctatgg gctgcccgtt tttataaaac
    29941 ccgcgcgctg gcccgtgaaa tgattgaagg cggtaaggtg cattacaacg ggcagcgcag
    30001 caagccgagc aaaatcgtcg agctgaatgc cacgctcact ctgcgccagg gaaatgacga
    30061 acgcacggtg attgtaaagg cgattactga acagcgtcgc cccgccagcg aggcagcctt
    30121 gctgtatgaa gagactgcgg aaagtgtaga gaaacgcgaa aaaatggcga tggcacgtaa
    30181 acttaatgcc ttaaccatgc cgcacccgga ccgacgcccg gacaaaaaag agcgccgcga
    30241 cctgttacga tttaaacacg gcgacagtga ataactgtca cctgcaagag agatgattat
    30301 gccgcaacat gaccaattac atcgctatct gtttgaaaat tttgccgttc gcggcgaact
    30361 ggtaaccgtt tcggaaaccc tgcaacagat ccttgagaac cacgattatc cgcagcccgt
    30421 taaaaacgtg ctggcagaac tgctggttgc gaccagcctg ttaaccgcta cgctgaagtt
    30481 tgatggtgat atcaccgtac agctgcaagg cgacggtccg atgaatctgg cggttattaa
    30541 cggtaacaat aaccagcaaa tgcgcggtgt ggcgcgcgtg cagggcgaaa ttccagaaaa
    30601 tgccgacctg aaaacgctgg tcggcaatgg ttacgtggtg atcaccatta ccccgagcga
    30661 aggcgaacgc tatcagggcg tggttggtct ggaaggtgat accctggcgg cctgcctgga
    30721 agattacttt atgcgttctg aacagctgcc gacgcgcctg tttattcgca ccggcgacgt
    30781 agacggcaaa ccggctgcag gcggtatgtt gttgcaggta atgcctgcgc aaaatgccca
    30841 gcaggacgac tttgaccacc tggcgacgct aaccgaaacc atcaaaaccg aagaactgct
    30901 gaccttaccg gcaaacgaag tgttgtggcg tttgtatcac gaagaagagg tgacggttta
    30961 cgatccgcag gatgtggagt tcaaatgcac ctgctcgcgt gaacgttgcg ccgatgcgct
    31021 gaaaacgctg cctgatgaag aagttgatag catcctggcg gaagatggcg aaattgacat
    31081 gcattgtgat tactgcggta accactatct gttcaatgcg atggatattg ctgaaatccg
    31141 caacaacgcg tctccggcag atccgcaagt tcattaatga gtatgtccgg cagagagggc
    31201 tctgccggat tttacgacgt aatggcctga tgtgctgcgc ttaccaggcc tgtgaaataa
    31261 atcgcaaatt attgttggtc agatacagcg tcgtatccgt taaaagagtt gtcacttact
    31321 taagtttatt tccagcgttt caccatctac cgtcagatcg cgccacgctt tcggcctcgt
    31381 ccccagtttt ccatccttcg cagctgtgag taatttttct ttcgttattt cgttcggaag
    31441 taaactcata tcaagcgcgt cccattcttt tctgtctgag tcaaagccat agacaatgac
    31501 tctgtcatca ttaaaagcaa acaggatccg ctccgcctga ccatcactat tcagatcttg
    31561 ctcgaccagg acgcaggcgt ctttttcaat acaggtcatc acgttatagc gatcctggat
    31621 taaggccgac cagaatgtcg catccggttt aacagaacca ggggcaatta acacattttc
    31681 ggctaatact ttttccgata cctgttcctg aagatgttgc tctccatcta acgccatcag
    31741 cagatcccgc gcgcgtttcg ggtctttcat aaacccggca tcgcttttca gcgactcaag
    31801 cgccgcacgt ccatagcgac cgctctgttc gagcatgtag atagttacct ggtctggcgt
    31861 gtttttgccg ctctgataac gcgccatatg actgttcacg ctaatacgca tactgtccag
    31921 caccggcgaa ttaagaagca ccagtatcac caacaccaat aacgaaaccg caaggttcac
    31981 tttgccctga agaacaaggg gattttgccc attacgccag acgatactga caaaataccc
    32041 cagcgaccac accagtaaca ccagcaccgc cagcgcgccc tgcaagcggt cgacagtcca
    32101 gccgtactga gcgacccgca gccataacgc ccaggcggcg acgaacacat acagcggagc
    32161 aaccagcaaa gcggttttaa tcaggcaacg caacggcccc gtccagggaa gtgacgcttt
    32221 ttgcggatcg cggacaataa ccattaagat caattgcaaa aaggccagcg ttaacagcaa
    32281 cccggcggcg gagatgtggc gagaaatcgc gctcaggccc gtaaacggca gagtgatgat
    32341 aaacatcagg gttagcaatg atactaacgg cagcaacccc gtggcgatta acgtgaacaa
    32401 cttttgaata gagtcgatta aacgtgactg tgtgcgcgcg agaatcaccg ccagtgcggt
    32461 aaccagacct aatgtaagat acataaacca gtcggttgca aaaaagagcg tattgaaaaa
    32521 cttgatgcca acaagtttaa acaactcacc ccacagtaaa agcaccagcc acgtcaagcc
    32581 attggcgaga aaaatcacca gtaatataag tacgttatgc catactgact ggtaaaaata
    32641 gcgatagcgg ctactgtcat tgcggatgcg aaggctttgt tgtatccacg gtagcaacaa
    32701 cattgccatc aacagcagat agcagccaaa atcccaaatc gccttttcag ctctccaggg
    32761 gttcatgcca tcagtttgcc acttcaacca gccgctcatc cccagcgtgg caataaacac
    32821 cagcgccagc catccccaaa ggcgcttctg tttaaaagag atcacggaga agagtaaaac
    32881 ggatgaaaac gcaacggtcg caggcacgcc ataaacaatc caactgtgat tttttccggc
    32941 aagccaggcg atcaacaggt agcaaaccag cccctgaagt aatccggtag caatcatccc
    33001 ccagcgtgtt gccggtgaaa gttcaacgtt atccatgttg gttatccaga atcaaaaggt
    33061 gggttaatta tcgcatccgg gcagtagtat tttgcttttt tcagaaaata atcaaaaaaa
    33121 gttagcgtgg tgaatcgata ctttaccgat tgaatttgca tcaatttcat taaggaatgc
    33181 gattccactc acaatattcc cgccatataa accaagattt aaccttttga gaacattttc
    33241 cacacctaaa atgctatttc tgcgataata gcaaccgttt cgtgacagga atcacggagt
    33301 tttttgtcaa atatgaattt ctccagatac gtaaatctat gagccttgtc gcggttaaca
    33361 cccccaaaaa gactttacta ttcaggcaat acatattggc taaggagcag tgaaatgcgc
    33421 gttaacaatg gtttgacccc gcaagaactc gaggcttatg gtatcagtga cgtacatgat
    33481 atcgtttaca acccaagcta cgacctgctg tatcaggaag agctcgatcc gagcctgaca
    33541 ggttatgagc gcggggtgtt aactaatctg ggtgccgttg ccgtcgatac cgggatcttc
    33601 accggtcgtt caccaaaaga taagtatatc gtccgtgacg ataccactcg cgatactttc
    33661 tggtgggcag acaaaggcaa aggtaaaaac gacaacaaac ctctctctcc ggaaacctgg
    33721 cagcatctga aaggcctggt gaccaggcag ctttccggca aacgtctgtt cgttgtcgac
    33781 gctttctgtg gtgcgaaccc ggatactcgt ctttccgtcc gtttcatcac cgaagtggcc
    33841 tggcaggcgc attttgtcaa aaacatgttt attcgcccga gcgatgaaga gctggcaggt
    33901 ttcaaaccag actttatcgt tatgaacggc gcgaagtgca ctaacccgca gtggaaagaa
    33961 cagggtctga actccgaaaa cttcgtggcg tttaacctga ccgagcgcat gcagctgatt
    34021 ggcggcacct ggtacggcgg cgaaatgaag aaagggatgt tctcgatgat gaactacctg
    34081 ctgccgctga aaggtatcgc ttctatgcac tgctccgcca acgttggtga gaaaggcgat
    34141 gttgcggtgt tcttcggcct ttccggcacc ggtaaaacca ccctttccac cgacccgaaa
    34201 cgtcgcctga ttggcgatga cgaacacggc tgggacgatg acggcgtgtt taacttcgaa
    34261 ggcggctgct acgcaaaaac tatcaagctg tcgaaagaag cggaacctga aatctacaac
    34321 gctatccgtc gtgatgcgtt gctggaaaac gtcaccgtgc gtgaagatgg cactatcgac
    34381 tttgatgatg gttcaaaaac cgagaacacc cgcgtttctt atccgatcta tcacatcgat
    34441 aacatcgtta agccggtttc caaagcgggt cacgcaacga aagttatctt cctgaccgca
    34501 gacgcctttg gtgtgctgcc gccggtttct cgtctgactg ccgatcaaac ccagtaccac
    34561 ttcctctctg gcttcaccgc caaactggcc ggtactgagc gtggcatcac cgaaccgaca
    34621 ccaaccttct ccgcttgctt cggcgcggcg ttcctgtcgc tgcatccgac tcagtacgca
    34681 gaagtgctgg taaaacgtat gcaagcggca ggtgcgcagg cgtatctggt taacactggc
    34741 tggaacggca ctggcaaacg tatctcgatt aaagataccc gcgctattat cgacgccatc
    34801 ctcaacggtt cgctggataa cgcagaaact ttcactctgc cgatgtttaa cctggcgatc
    34861 ccaaccgaac tgccgggcgt agacacgaag atcctcgatc cgcgtaacac ctacgcttcc
    34921 ccggaacagt ggcaggaaaa agccgaaacc ctggcgaaac tgtttatcga caacttcgat
    34981 aaatacactg acaccccagc gggtgctgcg ctggtagcgg caggtccgaa gctgtaatca
    35041 gctgatatct cattgacccc ttatccaaac ggataagggg tttttttata tctgattagc
    35101 tatcaatatg tacacggtac acttataata atcaatagac cgcaggatgc attatgttca
    35161 cctttattga actacaagga tttagcaaac gccgccagtt attgttacct gatgatgagt
    35221 tccgggcttt tcaggaacta ctcattcaag atcccactgc cggtgacatt atcgcaggca
    35281 caggcagttt tagaaaaatt cgctggaacc gttctggaat ggggaaacgg ggtggcattc
    35341 ggataattta ttacaacgta acacgcaatg gccgaattta tctggcgttg atttatccta
    35401 aaaatgaaca ggatgattta acagaagaac aaagaaaggc attgaaacta ttgtcagaga
    35461 agctgcttta atgttgaagc tccacaaatt ccaccatggt cgaaatgcca acggagacat
    35521 tgaaaacaga tgaaagatga attatttgct gatcttcttg ccagcgcaga agaaatggta
    35581 cgcatcgaaa agggtgaaga aacgcctgaa ccagagcacg tccatacttt tagcgagatc
    35641 gatgtaaaag cgatccgtga agcaacgggt ttacgtcagc aagattttgc tgtcgccgta
    35701 ggggtaagtt atgacctggt caaaagctgg gaaaccaaac gccgtcagcc taccggagca
    35761 cctcgaaaat tgctcctgct tttgcaagcg aatcctttca ttatcaatca attgaaaaca
    35821 atctaaaaac gggagacacc ttcgcctccc gttttattta cccttctttt gtcgtgccct
    35881 gcgcccgcgt taccggcact ggcagccagg cgcgaatgga aagcccgccc cgctcgctgg
    35941 tgccaagctc cagcatcccg ttatggttat ccacgatacg ctgcacaatt gccagcccta
    36001 atcccgtgcc gctaatggtg cgcgcactgt cgccgcggac aaacggctgg aacaggtgct
    36061 tacgttgttc cggcgcaatt cccggaccgt catcttccac ctggaaccag gcgcgattcg
    36121 gctccgttcc gctgctgact ttgatccagc cattgccata acgggcggcg ttgaccacca
    36181 tattcgccac cgcgcgtttg atcgacagcg ggtgcatttt cacttcaatg ctgccggggt
    36241 aaagcgcggt ttcaatttcc cgctcatagc cactttcggc agcaatcacc tcaccgagta
    36301 ctgcattaag atccgccatt tccatcggca tctcctgccc ggtgcgcagg tagtcgataa
    36361 actgctcaat gatggcgttg cactcttcga tatctttatt gatcgattct gccagatagc
    36421 catcctgctc gctcatcatc tcagtcgcca ggcgaatacg cgtcagcggc gtgcgcaagt
    36481 cgtgacttac ccccgccatc agcagcgtgc ggtcatccgc cagttgctta acaccagccg
    36541 ccatatggtt aaaggcacgg gtaacggaac gcacctccga agcgccatat tcacgcagcg
    36601 gcggcggaat aatcccttta ccaacctgca aggctgcgtg ttcgagatcg accaacggtc
    36661 ggttctggat acgaataaac agccacgccc cgcctatcgc caatagcata atcgccagcg
    36721 tatagcggaa cagcggagag aaatcgccct gatgaatttc ggtcagcggc acgcgtaccc
    36781 agatattggg cgacagccag gttttcagcc agacgacagg cgaacttttg ttgacctcaa
    36841 cgcgcacttc cgtcgggccg cccagttgct gtgccatctg atggcttaag aattcatagt
    36901 gttgcgccca acgcagacct gcctcttcgg cagcctcgtt ggagtagaga gagatcccca
    36961 gctcacggta gatctcccga cggaaagcgg gaggcacaac caactgcgtg ccgtcctcca
    37021 gttgcagttt gtcggtcatc aacatacgca cttcgtacgc gaggacttta ttaaactgct
    37081 ggaggctcgg caaaatcgcg aagttcagca ccaccagata agttgtcacc aggctggcga
    37141 acagcaaggt gacgatgagc aataacgtac gggcaaatga acttcgtggc gagaagcgca
    37201 atcgcctcat gctttagagc cgtccggtac aaagacgtag cccaggcccc aaacggtctg
    37261 aatgtaacgc ggatgcgctg gatcttcttc taccatgcgg cgcagacgcg aaatctgcac
    37321 gtcgatggag cgttccattg cggaatattc acgaccacgg gcaaggttca tcagcttatc
    37381 gcgggagagc ggctcacgcg gatggctgac cagtgccttc agtaccgcaa actcaccgct
    37441 ggtgagcggc atcggctcgt cttcgcggaa catttcgcgc gtaccgaggt taagtttgaa
    37501 cttaccgaaa gcaattaccg cctcttcctg tgatggtgcg cctggtagct cgttcgcctg
    37561 acgacgcagc accgcacgga tacgggccag cagttcacgc gggttaaacg gttttggaat
    37621 gtaatcgtca gcgccaatct ccaggccaac gatacggtcc acttcttccc ctttcgccgt
    37681 caccataatg atcggcatcg ggttgctctg actacgaaga cgtcggcaaa tcgacaagcc
    37741 atcttcacca ggtaacatca aatccagtac cataagatgg aaagattcac gagtcagcag
    37801 gcgatccatc tgttctgcat tagcgacgct tcgaacctgg aagccttgtt cggtgagata
    37861 acgttccagc agcgcacgca ggcgcatgtc gtcatcgacc accagaatct tgtagttctc
    37921 ttgcattgtt tgtactccca aaggttcgca acaatttgta agcgtgtatt cttaaaaaag
    37981 ctcacgttcg tcaccagcta aatctggtat gaatttcagc ctaaattgtt acaaagcata
    38041 ttaaacagca gcttaagtat acaatttatt cggcgaaaca ttattgattc tgttgatatg
    38101 atcacgttat acccaatgtg cgcattatca aacagacaaa gggaatcaac gagatgaaaa
    38161 cgcccctggt tacccgggaa gggtatgaaa aactcaaaca agagcttaat tatctctggc
    38221 gtgaagaacg cccggaggtc acaaaaaagg tgacctgggc cgcaagtctg ggcgaccgca
    38281 gcgaaaatgc tgactatcag tataataaaa agcgcctgcg tgaaatcgac cgtcgcgtgc
    38341 gctatctcac taaatgcatg gaaaatctca aaatcgtcga ttactccccg cagcaggaag
    38401 gcaaggtctt ttttggcgca tgggtggaga ttgaaaacga cgatggcgtg actcaccgtt
    38461 tccgtattgt cggctacgat gaaatttttg gccgtaaaga ttacatctct atcgattccc
    38521 cgatggcccg cgcattgctg aaaaaagaag tcggcgatct ggcggtggtg aatacccctg
    38581 ccggggaagc gagctggtat gttaatgcta tcgagtacgt gaaaccgtaa ggaagagtct
    38641 taacctcctg ccgatggctg gcatttttgc cagccagtcc gtataactat cccctgattt
    38701 ttgatccgaa aagatgaact caaaccatga tgaatgattc gttctgccgc attattgcgg
    38761 gtgaaattca ggcgcgcccg gaacaggttg acgctgccgt tcgcctgctt gacgaaggga
    38821 ataccgtgcc gtttatcgca cgttatcgta aggaaatcac cggcggtctg gatgacacgc
    38881 agctgcgtaa tctggaaacg cgtctgggat acctgcgcga actggaagag agacgtcagg
    38941 cgatcctcaa atccatttcc gagcaaggca aactcactga cgagctggcg aatgccatca
    39001 acgccacctt aagcaaaacc gaactcgaag acctctacct gccctacaaa cctaaacgcc
    39061 gcacccgcgg gcaaatcgcc attgaagcag ggcttgagcc gttggctgac ctgctgtgga
    39121 gcgatccgtc acacacgcca gaagtcgccg ctgcacaata tgttgatgcc gataaaggcg
    39181 tggcagatac caaagccgcg ctggacggcg cgcgctatat cctgatggaa cggtttgccg
    39241 aagatgccgc gctgctggca aaagtgcgtg attatctgtg gaagaacgcg catctggtct
    39301 caaccgtggt gagcggtaaa gaagaggaag gggcaaaatt ccgcgactat ttcgatcatc
    39361 acgaaccgtt gtccacggtg ccttctcacc gcgcgctggc gatgttccgt gggcgtaacg
    39421 aaggcgtact ccagctttcg ctgaatgccg atccgcagtt cgatgagccg cccaaagaga
    39481 gctattgcga gcaaatcatc atggatcacc ttggcctgcg cctgaacaat gccccggcgg
    39541 atagctggcg caaaggcgta gtgagctgga cctggcgcat caaggtgctg atgcatctgg
    39601 aaaccgaact gatgggtacc gtgcgcgaac gcgcggaaga tgaagcaatc aacgtctttg
    39661 cccgtaacct gcacgatctg ctgatggcgg cccctgccgg actgcgtgca acgatgggcc
    39721 tcgatccggg tctgcgtact ggggtaaaag tggcggtggt cgatgccact ggcaaactgg
    39781 tagcgaccga taccatttac ccgcacaccg gacaagccgc aaaagcagcg atgactgttg
    39841 ctgcgctgtg tgaaaagcat aacgttgaac tggtggcgat cggcaacggt acagcttccc
    39901 gcgaaaccga acgtttctat ctcgacgtgc agaagcagtt cccgaaagtg accgcacaga
    39961 aagtgatcgt cagcgaagct ggcgcgtcgg tttactcggc ttccgagctg gcagcgcagg
    40021 agtttccgga tctcgacgtt tcgctgcgtg gcgcggtgtc tatcgcccgc cgtttgcagg
    40081 atccgctggc ggagctggtg aaaatcgatc cgaaatctat cggcgtaggt cagtatcagc
    40141 atgacgtcag ccagacgcaa ctggcccgca aactggacgc agtagtagaa gactgcgtaa
    40201 acgccgttgg cgtcgatctc aacactgctt ctgttccgct gttaacccgc gtggcgggcc
    40261 tgacgcgcat gatggcgcaa aacatcgtgg cctggcgcga tgagaacggt cagttccaga
    40321 accgtcagca actgctgaaa gtgagccgtc tggggccgaa agccttcgag cagtgcgcgg
    40381 gcttcttgcg cattaaccat ggtgataacc cgctggacgc gtctaccgtc cacccggaag
    40441 cctatccggt ggtggaacgc attctggcag caacacagca ggcactgaaa gatctgatgg
    40501 gtaacagcag cgaactgcgt aacctgaaag cgtctgactt tactgatgaa aaattcggtg
    40561 tgccgacagt aactgacatc atcaaagagc tggaaaaacc gggtcgcgat ccgcgtccgg
    40621 aatttaaaac cgctcagttt gccgatggcg tcgagacaat gaacgacctg caaccgggta
    40681 tgatcctcga aggtgcggtg accaacgtca ccaactttgg cgcgtttgtc gatatcggcg
    40741 tgcatcagga cggcctggtt cacatctctt cattgtcgaa caagtttgta gaagatccgc
    40801 ataccgtggt gaaagcgggc gacattgtga aggtgaaagt gctggaagtg gatcttcagc
    40861 gtaaacgtat cgccctgacc atgcgtctgg acgagcagcc tggcgaaacc aacgcccgtc
    40921 gcggcggcgg taatgaacgc ccgcaaaaca accgcccggc agccaaaccg cgcggacgtg
    40981 aagcgcagcc tgccggtaac agcgcgatga tggacgcgct ggcggcagca atgggcaaaa
    41041 aacgttaaac gccctgattg acccctaaac ctgcgcgata aggtgtccac gccgcatctg
    41101 gcaacgaacg ccttgtctga cataaaagtg ccggagaata tctccggcat ttttattcca
    41161 cagccaaact cacaatatat tccggcaaca tttatcactt cattaacaac tgaaacctta
    41221 attaaacatt agccagtcct ggtaattcgc tattcgaatt atattttcgc tgcgatataa
    41281 ccttgagcca catcaacatt gagtcagatt attattcaaa ccaacattcg cacacatttt
    41341 aagtattgct gatagaaacc attctcatta tcattgtgtt gttgattatt taatctctcc
    41401 tttgttggca aatcatctgg tctcatgtcg ctgtcaaacg ccccatgagg tagttatcca
    41461 gttaatgaga aacaagtagg cacctatgca atacactcca gatactgcgt ggaaaatcac
    41521 tggcttttcc cgtgaaatca gcccggcata tcgccaaaaa ctgctttctc ttggcatgtt
    41581 acctggctcc tcttttaatg tggtgcgcgt cgctccactc ggcgacccca ttcatatcga
    41641 aacccgtcgt gtgagcctgg tattacgcaa aaaagatctg gccttattag aagtggaagc
    41701 ggtttcctgt taatacggtg ataacaacaa tgaaaaaatt aaccataggc ttaattggta
    41761 atccaaattc tggcaagaca accttattta accagctcac tggcgcacgt cagcgtgtag
    41821 gtaactgggc tggcgttacc gtcgaacgta aagaagggca attctccacc accgatcatc
    41881 aggtcacgct ggtggacctg cccggcacct attctctgac caccatctca tcgcagacct
    41941 cgctcgatga gcaaatcgcc tgtcactaca ttttgagtgg cgacgccgac ctgctgatta
    42001 acgtggtgga tgcgtctaac cttgagcgta acctgtacct gacgctacaa ctgctggaac
    42061 tcggcattcc ctgcatcgtg gcactgaaca tgctcgacat tgccgagaag caaaatattc
    42121 gtattgaaat tgatgctctg tcggcgcgtc ttggctgccc agtgatcccg ctggtttcaa
    42181 cccgtggtcg cggtattgaa gcgctcaagc tggcgattga tcgctataaa gctaacgaga
    42241 atgtggaact ggtgcattac gcacagccgc tactcaacga agcagattca ctggcaaaag
    42301 tgatgccttc cgacatcccg ctgaaacaac gtcgctggct gggcctgcaa atgctggaag
    42361 gcgatatcta cagccgcgcc tacgccggtg aagcgtcgca gcatctggat gccgccctcg
    42421 cccgtctgcg taatgagatg gacgatccgg cgctgcacat tgccgatgcg cgttaccagt
    42481 gcattgctgc catctgtgat gtggtaagca acaccctgac ggcagaaccc agccgtttca
    42541 ccactgcggt agataaaatc gtgctcaacc gtttcctcgg tctgccgatt ttcctctttg
    42601 tgatgtacct gatgttcctg ctggctatca acatcggcgg ggcgttacag ccgctgtttg
    42661 acgtcggctc cgtggcgcta tttgtgcatg gtattcaatg gattggctac acgctccact
    42721 tcccggactg gctgactatc ttcctcgccc agggcctggg tggcggcatt aacaccgtgc
    42781 tgccactggt gccgcagatt ggcatgatgt acctgttcct ctccttcctt gaggactccg
    42841 ggtatatggc gcgtgcggcg tttgtgatgg accgtctgat gcaggcgctg ggcttgccgg
    42901 ggaaatcctt tgtgccgctg atcgtcggtt tcggttgtaa cgtaccgtcg gtaatgggtg
    42961 cacgtacgct tgatgcaccg cgtgaacgtc tgatgaccat catgatggca ccgtttatgt
    43021 cctgcggcgc gcgtctggct atcttcgcag tattcgcggc tgccttcttc gggcagaacg
    43081 gtgcgctggc ggtcttctcg ctgtatatgc tgggtattgt gatggcggtg ctgactggcc
    43141 tgatgctcaa gtacaccatc atgcgcggtg aagcgacgcc gtttgtcatg gagttgccgg
    43201 tctatcatgt accacacgtt aaaagcctga ttatccagac ctggcagcgt ctgaaaggct
    43261 tcgttctgcg tgctggtaaa gtgatcatca tcgtcagcat tttcctgagc gctttcaaca
    43321 gcttctcgct gagcgggaaa atcgtcgata acatcaacga ctcggcgctg gcgtccgtca
    43381 gccgggtgat caccccggtc ttcaagccaa ttggcgtgca tgaagataac tggcaggcaa
    43441 cggttggcct gtttacaggt gccatggcga aagaagtggt agtgggtacg ctcaacaccc
    43501 tctacaccgc agaaaatatt caggacgaag agttcaatcc ggcagagttt aacctcggtg
    43561 aagagctgtt cagtgcgata gatgaaacct ggcagagcct gaaagacacc ttcagcctta
    43621 gcgtactgat gaaccccatt gaagccagca aaggcgacgg cgaaatgggt accggggcga
    43681 tgggcgtgat ggatcagaaa ttcggtagcg cagcagcagc ttacagctac ctgattttcg
    43741 tcctgctgta tgtaccatgt atctcggtga tgggagccat cgcccgtgaa tcaagccgtg
    43801 gctggatggg cttctccatc ctgtgggggc tgaatatcgc ttactcgctg gcaacattgt
    43861 tctatcaggt cgccagctac agtcagcacc caacttacag cctggtgtgc attctggcgg
    43921 ttatcctgtt taacatcgtg gttatcggtc tgctgcgccg cgcgcgtagc cgggtggata
    43981 tcgaactgct ggcaacccgc aagtcggtaa gcagttgctg cgcagccagc accaccggtg
    44041 attgccatta atggcttcac ttattcaggt gcgcgatttg ctggcgttac ggggccgtat
    44101 ggaagcggcc cagataagcc agacattgaa cactccacag ccaatgatta acgccatgct
    44161 gcaacaactg gaaagtatgg gcaaagccgt gcggattcag gaagaacctg acggctgcct
    44221 ctctggcagt tgtaaaagct gcccggaagg aaaagcctgt ctgcgcgagt ggtgggcgct
    44281 gcgttaacct tactccatcg cctgttttgg aaagcccggt atgcgtctgc atccgggctt
    44341 ttttgcgtgc ggctttccat aaaaatgcaa ctcttgcagc acggcgtaag ttcctttgaa
    44401 agcatctcgc agggatgaaa actcgctaat gcacagatgt ggagtggcgc gtagagtcgc
    44461 ggcattcaaa caacaggtga aggaacgcca tgagtaaaaa gcagagttcc accccacatg
    44521 atgcgctgtt caaactcttt ttacgccaac cggacacggc tcgcgatttt cttgcgttcc
    44581 atttaccggc ccccattcac gcgctctgtg atatgaaaac cctcaagctg gagtcgagca
    44641 gctttattga tgacgatcta cgtgaaagct attccgatgt gctgtggtcg gtgaaaacgg
    44701 aacaaggacc aggatacatc tattgtctga ttgaacatca aagcacctca aacaaactga
    44761 tcgcatttcg catgatgcgt tacgctattg ccgcaatgca aaatcacctt gatgctggat
    44821 acaaaacgtt gccgatggtg gtgctattgt tgttttacca cggtattgaa agcccctatc
    44881 cctattcgct gtgttggctg gattgtttcg ccgatcccaa actggcaagg cagctttatg
    44941 cctccgcatt tccgctgatt gatgtcaccg tcatgcctga tgatgaaatc atgcagcacc
    45001 gacgtatggc gctgctggag ttaattcaaa aacatattcg tcaacgcgac ctgatggggc
    45061 tggtagagca aatggcctgc ttattaagta gtggatacgc taatgacaga caaatcaaag
    45121 ggctgtttaa ttacatactg caaaccggcg acgcggtacg ttttaacgat tttatcgacg
    45181 gcgttgccga acgttcaccg aaacacaagg agagtttaat gacaattgcg gaaagattgc
    45241 ggcaggaggg ggaacaatcc aaagccctgc atatagccaa aataatgctt gaatccggag
    45301 tccctcttac agacatcatg cgctttaccg gggtgtcaga agaagagttg gctgcggcga
    45361 gccagtaaat ttctgtctcg ccatttcaaa agttgcctac accctctgct tcaacgccac
    45421 cagcaggtga caaaactcga ccggatgcga aataaacggc gcatgggccg ctttggcgaa
    45481 gatatatgat tcgctgtgag gccaaagttt atccagcatc ggcaccactt tgcgcggcac
    45541 cagaccgtcg agatagccat acaatcgcaa aaacggcatg ggcacgtttt gcagcggctg
    45601 acggagatcg accgttttca ggatttccag cccgccatta agcacgtcaa cctccggcat
    45661 cggtaacgcc agaacggttt tcttcaacgc ccgcgcatcc tggcgcgccg tttcagtgcc
    45721 catggtttgt aacgccagga accgctccac tgtacgctga aaatcatcac tgagttgctg
    45781 ctgaaatccc gccagcacgt ccggttttat ccccggccac tcgtcacgag cactaaaaca
    45841 aggtgacgac gccacggtga ccagcgcctg aacacgctcg ggatgggtta acgcaatctg
    45901 gcttgccacc agcccgccca gactccagcc taaccaaatg gctttatcag gtgcctgttg
    45961 cagcacggct tcggccatat cagcaagtga cagcgcacca aatccccggc tacgcccgaa
    46021 gccgggcagg tcaacaaggt gcagcgtaaa atgcgagcta agttcctcgt caatgcaacg
    46081 ccacacttcg gcattcagtc cccatccgtg cagcagcaca agatgaacat tcccctgacc
    46141 tttggtctgc caccagatgt tattcatccg ctattgttct cttttgactt acaaggatga
    46201 acatatgcta acagtaccgg gattatgctg gctatgccga atgccactgg cgttaggtca
    46261 ttgggggatt tgttcggtct gttcacgcgc cacccgcaca gataaaacgt tatgcccaca
    46321 atgtggatta cccgccacac actcccatct tccctgcggt cgctgcctgc aaaaaccgcc
    46381 gccctggcaa agactggtca cagttgccga ctatgcgccg ccgttaagtc tgctcatcca
    46441 ccagcttaaa ttttcccggc gcagtgaaat cgccagcgcc ctgtcacgtc tgttactatt
    46501 ggaagtcttg cacgctcgtc gcaccaccgg gttgcaattg ccggatcgca tcatcagcgt
    46561 tccgttatgg cagcggcgtc actggcgtcg gggatttaat cagagcgatt tgctgtgtca
    46621 gccgttatca cgctggttgc actgccaatg ggatagcgaa gccgtcacac gtacacgggc
    46681 cactgcgacc cagcattttc tcagtgcccg gctgcgcaag cgcaacctga aaaatgcctt
    46741 tcgtcttgaa ttgcccgtgc aaggtcgcca tatggtgatt gtggatgatg tcgttaccac
    46801 cggaagtacc gtcgcagaga ttgcgcagtt gcttttacgc aatggtgcgg cgactgtcca
    46861 ggtctggtgc ctttgtcgaa ccttgtagag cctcgatgat gggcgtatta taaccaacta
    46921 aaatagtcaa ctattaggcc attactatga tccgtatttc cgatgctgca caagcgcact
    46981 ttgccaaact gctggcaaat caggaagaag ggacacaaat ccgcgtattt gtgattaacc
    47041 ctggcacgcc taacgctgaa tgtggtgttt cttattgtcc gccggatgcc gtggaagcca
    47101 ccgacactgc cctgaaattt gacctgctga ccgcgtatgt tgatgagtta agcgcaccat
    47161 acctggaaga tgcagagatc gactttgtta ccgaccagtt gggttctcag ttaacgctga
    47221 aagccccgaa cgccaaaatg cgtaaagtgg cagacgatgc accgctgatg gagcgcgtgg
    47281 agtatatgct gcagtcgcag atcaacccac agcttgctgg tcacggtggt cgcgtttcgc
    47341 tgatggaaat cacagaagac ggttacgcca ttctgcaatt tggcggcggc tgtaacggtt
    47401 gttccatggt cgatgtgacg ctgaaagaag ggatcgagaa gcagctgctg aacgaattcc
    47461 cggagctgaa aggtgtgcgc gatctcaccg aacaccagcg cggcgaacac tcctactact
    47521 aagttatccc ctcttttgta gattgcccga tgcgacgcta aagcgtcatt tcgggcctac
    47581 gttgaacatg tgccagacgt tggcacagca ttgctttggc aaatccctcc cttcgtttcc
    47641 ccgcgataat atgaccaacc tctcataatt taaatttacc ccgctctggt gattctcaaa
    47701 cgccagatgt tacccgtatc attcacatgg gtaccaaaca tactcctgac atctgactac
    47761 aataattagt tttagtgggt atcagtcgtg gtgccgcaat atctctgttc ccgattggga
    47821 taattagagt ttgtcgtcag aaaattgacg ttacccataa caaatgaaag gccaggtaaa
    47881 tcatgccatt agtcattgtt gctatcggtg taatcttgtt gttgctcctg atgatccgct
    47941 tcaaaatgaa cggcttcatc gctctcgtcc tcgtggcgct tgctgttgga ttaatgcaag
    48001 gaatgccgct ggataaagtt attggctcca tcaaagccgg tgtcggcggg acgctcggta
    48061 gccttgccct gatcatgggt tttggcgcaa tgctgggcaa aatgctggca gactgcggtg
    48121 gcgcacaacg tatcgccacc acgctgattg ccaaatttgg taaaaagcac atccagtggg
    48181 cggtggtgtt aaccggtttt accgttggtt ttgccctgtt ctatgaagtg ggcttcgtgc
    48241 tgatgctgcc tctggtgttt accatcgcgg cttccgcgaa tattccactg ctgtatgttg
    48301 gtgtaccaat ggcggctgca ctgtctgtga cccacggctt cctgccaccg catccgggcc
    48361 cgactgcgat tgccaccatt ttcaatgccg atatgggtaa aaccctgctg tacggtacta
    48421 ttctggcaat cccgaccgtg attctcgccg gtccggttta cgctcgcgtg ttgaaaggta
    48481 tcgataagcc aatcccggaa ggtctctaca gcgcgaaaac cttcagcgaa gaagagatgc
    48541 cgagctttgg cgtcagcgtc tggacttctc tggtgccggt tgtgctgatg gcgatgcgtg
    48601 cgattgccga aatgatcctg ccgaaaggtc acgctttcct gccggtagcg gagttcctcg
    48661 gtgacccggt aatggcaacg ctgattgccg tgctgattgc gatgttcacc tttggtctga
    48721 accgtggtcg ttcaatggat cagattaacg acacgctggt ttcttccatc aaaatcattg
    48781 cgatgatgct gttgatcatc ggtggtggcg gtgcgttcaa gcaggtgctg gtagacagcg
    48841 gcgtggacaa atacattgct tccatgatgc acgaaaccaa catttctccg ctgctgatgg
    48901 cctggtcgat tgctgccgta ctgcgtatcg cgctgggttc cgcaaccgtt gcggcaatca
    48961 ctgcgggtgg tatcgcggca ccgctgattg caacgacggg tgttagccca gagctgatgg
    49021 ttattgcggt gggttccggt agtgtgattt tctctcatgt gaacgatccg ggcttctggc
    49081 tgttcaaaga gtactttaac ctgactatcg gcgagaccat caaatcctgg tcgatgctgg
    49141 aaaccattat ctcggtgtgc ggtctggtag gctgtctgct gctgaatatg gtgatttgat
    49201 aacactgact gccggatgca tcgcatccgg catcaaccgc actctacttc ttcttcgctg
    49261 cagctctgcg ccgtctgtcc aaatccttca gcaacttgtt cacgccatca tcggcaaaca
    49321 tcgtctcaag cgttgcggaa agcttgcgtc gccagttttt atactggtaa ctggtgccag
    49381 gaatattcac cggttcggcc atatccagcc agtcttccgg ctgtagtcct aacagagcac
    49441 tgttactgtc ggcaatgtag cgctgcaaac cacggttcag cgtcggcgtc atcgacatca
    49501 acgatgcctt atgcccggca cgttttggca gacaaccata tttatgcagt gcatccagca
    49561 gcccttgctt cgccagttcg cgatcctgat acagaccgcg cagtaccact tcatccggat
    49621 acagccccag ggttttgccc agcgttagat ccccgctctc ccagtaaccg cgtagcgtag
    49681 gcaggtcatg tgtcgccgca accgccatcg actgctccgg atacgctttc ggtgcacgga
    49741 acgtcttctc gtggtcgttt tcgaaataga gcactttgta ggagtacaca ccgctgctgc
    49801 gcagcttacc gacaatctct accggtacgg taccgagatc ttcaccaatc accatacagc
    49861 gatgacgttt actttcgagt gccagaatcg agagcagatc atccaccgga tagtgaacat
    49921 acgcgccctg atctgccgtc tcgccatacg gtatccacca caaacgcagc atcgacatca
    49981 catggtcaat tcgtaatgcg ccgcagtttt gcatattggc acgcaacagc tcgataaacg
    50041 gttcataggc acgcgcggtg atgatatgcg ggtccattgg cggtaatccc cagttctgcc
    50101 ccaacgggcc gaggatatcc ggcggcgcgc caaccgacgc tttcaggcaa tatagttcac
    50161 ggtcacacca ggtttccgcc ccaccttccg ctacgccaac cgccagatca cgatacaagc
    50221 caatcggcat ttcatagccc tggcttatct cccagcaggc ggcaaactgg ctgtaagcca
    50281 gccactgcaa ccagagataa aaatcgacgt cattacgatg ttcttcgcag aactgacgca
    50341 cttctggtga atccacgttc tgatacatct ctggccatgc aggccagccc cagcgcattt
    50401 cgtcctcttt cacttgctgg gcatgtagcg catcaaaggc tgcctgccag aacaggctgt
    50461 cgccctgctc tgcaacaaac tggcgaaacg cggtcatctg ctcatcatca cgttgcgcga
    50521 aacctttcca cgccattcgt aatgctgtca tttttagggc ggtaaccgtg gagtaatcga
    50581 cccagtcggc atcgcgcgcc tgttgcagcg tctgttgcgt ggtcggcaac tgccaccagg
    50641 cctgagcctc ttcgctaaga tggaaatctt caacggcgtt aacgtcgata taaatcacat
    50701 tcagccaacg gcgagaagac gggctgtatg ggctggcact ctccggattt gccggataga
    50761 gcgcatgaat cgggttcagg ccgatgaacg acccgccacg ttttgccaca tccaccagca
    50821 tcgctttgag atcgccaaaa tccccaatac cccagttttt ttccgatcgc agcgtataaa
    50881 gctgaacgca ggcaccccac agcttttgtt tattcagcaa cgcctgcggt tcgtaacagc
    50941 gtttcggggc gacaatcacc cggcaatgcg cgcgctggtc gtcctgggtg agtgtcagcg
    51001 tgtgataacc ttccggcagc ttcgtcggta gattgaacgc tttgcccccc gttacatggc
    51061 ctttgtactg tgttccttct tcggtggtca gcagccagct atattcgccg ctgccctcca
    51121 ccaccatcgg catttttttg ccgctggtat aaaccatgac attcgggact ggcgttaccg
    51181 ccactttcgt ggcggtacgt tgatgcatcg cgtcaagcaa acgccgtttg gtttcggcgc
    51241 taatcgactg cggtttaccg tgggcattga tgtaattggg gctaatcccc gccgccagcg
    51301 cggcattatc cagacgtttg ctttccatcg agcttcctta gcgttttgcc tgccagatac
    51361 gagcctgata atcgcgaata gagcgatccg agctaaacat accgcagcgg gcggtattga
    51421 ggatcgccgc gcgagtccag gcctcctggt cgcggtacag cacatccacc tgcttttgtg
    51481 cctcaacata ggctgcgaaa tccgccatca ccagatacgg atcgccgcct tgtttgccga
    51541 tactgtgcag catctggtcg aaggcatgct tatcgccgtc gctgtattta ccgctttcca
    51601 gctctttcaa tactgcgtcc agcaccttat ctttcttccg ccatttcacc gggtcgtagc
    51661 ctttggccag aatagccttc acttgttcca cggtatgacc aaaaataaag atattttctt
    51721 caccgacttt ctcggcgatt tcaacgttcg caccatccag cgtaccgaca gtaagcgcac
    51781 cattgagcgc cagtttcata ttgccggtac cggaagcttc tttacctgca gtcgaaattt
    51841 gttcggagat atccgccgcc gggatcagtt tttccgccgc cgaaacgcaa taatccggca
    51901 ggaacaccac cttcaactta tcgccaacca gtggatcgtt gttgatcacg tcagccactt
    51961 tgttgatcgc aaagataata ttcttcgcca ggtagtagcc cggtgccgct ttcgcgccga
    52021 agaggaagac gcgcggtacg cgatcagcct gcgggttttc acgaatttct ttgtacaacg
    52081 ccagaatatg cagcagattc aggtgctggc gtttgtactc atgcagacgt ttgatctgaa
    52141 tatcgaaaat cgcctgtgga ttgatctcaa taccggtacg aactttcaca aactccgcca
    52201 gacggacttt attcgcctgc ttgatctcgc gatattgctg acggaatttc gcatcatcag
    52261 cgaatttttc cagattgatc agctgatcga gatcgttagc ccactctttt tgcagtgatt
    52321 tatccaacag agccgccagt gcagggttgc actgtttgat ccagcgacgt ggggtaatac
    52381 cgttggtgac gttatggaat ttgttcggcc atagctggtg atattccggg aacagatctt
    52441 tcaccaccag atccgagtgc agcgccgcaa caccgttcac cgcgaaaccg ccaaccacac
    52501 acaggttcgc catatgcact tgtttatcgt gcaccaccgc cagtttggcc cacacttttt
    52561 catcgcccgg ccaggttttc tccaccagcg ttttaaagcg agtattaatt tcgttaataa
    52621 tctgcatatg gcgcggcagt aagcctttca ccagtttcac atcccagcgt tccagcgctt
    52681 ctggcatcag ggtatggttg gtgtaagcga aagttttgct ggtaatggcc caggcgtcat
    52741 cccagctcat ctggtgctca tcgatcagca cgcgcagcag ttctggaatc gcgatagttg
    52801 ggtgggtatc gttcagctga ataacttcgt aatccgccag ttcgtgcagt ttacgccccg
    52861 ccagatgatg gcgacgcaaa atatccgcta ccgaacaggc acactggaag tactgctgca
    52921 tcaagcgcag ctttttaccg gcagtatggt tgtcgtttgg atagagaact ttggtcagtt
    52981 tttccgcatt gatgccctgc tgttcggcac gcaggaaatc accgtcgtta aatttagtca
    53041 gatcaaacgg atgcgcgtgc gtcgcctgcc acagacgcag cggctgcgcc acgccattac
    53101 gatagccgac aacggggaga tcccacgctt gaccggtaat ggtaaactcc ggctcccagc
    53161 gtccgtcttt cgtcacttta ccgccaatcc ctacctgcac atccagtgct tcgttgtggc
    53221 ggaaccacgg gtagttactg cgatgccagt catccggcgc ttcaacctgt ttgccatcga
    53281 caaaagactg gcggaacaaa ccatattgat agttcagacc gtaacccgtc gcagactgac
    53341 cgacagttgc cattgagtcg aggaagcacg ccgccagacg tcccagacca ccgttaccca
    53401 gcgccgggtc gatctcttct tccagcaggt ccgtcagatt gatgtcataa gccttcaacg
    53461 aatcctgtac atcctgatac cagccgagat tcaacaggtt gttgcccgtc aggcgaccaa
    53521 tcaaaaactc cattgagatg tagttaacat gtcgctgatt cgccaccggc ttggcgaatg
    53581 gctgagcacg cagcatttcg gccagtgctt cactcactgc tagccaccac tggcgaggag
    53641 tcatttcagc cgcagaattt aagccataac gctgccactg acgtgaaagc gcttcctgaa
    53701 attgcttatc gttaaaaata ggttgtgaca taggagttcc acttttctta gattttcaac
    53761 acaacgttat cgctagtttg ccaggctcga tgttgacctt cctcatcctg cgggggatta
    53821 ggcagggagg agttgcgggg atgagcaagg aaatgtgatc tcaaccactt aaagctagtg
    53881 caaaccacag gattagcagc aaatcaatgc aatacagcgc agaaaatctg tatctaagtg
    53941 caaaaaatgg ccgttgcgta ttttcaaaaa gcggaaggta actctataaa ttaagtaaag
    54001 gagtgaaaca gtttcataag taaaatatcc agtgtgctcc atctcattct taatagattt
    54061 attaagatca tctttttaga tggcactttc atcaggaatg aagaagaaac ccttgcttaa
    54121 atgaatctga tgaacataag ggaaaccagt attcacgctg gatcagcgtc gttttaggtg
    54181 agttgttaat aaagatttgg aattgtgaca cagtgcaaat tcagacacat aaaaaaacgt
    54241 catcgcttgc attagaaagg tttctggccg accttataac cattaattac gaagcgcaaa
    54301 aaaaataata tttcctcatt ttccacagtg aagtgattaa ctatgctgat tccgtcaaaa
    54361 ctaagtcgtc cggttcgact cgaccatacc gtggttcgtg agcgcctgct ggctaaactt
    54421 tccggcgcga acaacttccg gctggcgctg atcacgagtc ctgcgggcta cggaaagacc
    54481 accctcattt cccagtgggc ggcaggcaaa aacgatatcg gctggtactc gctggatgaa
    54541 ggtgataacc agcaagagcg tttcgccagc tatctcattg ccgccgtgca gcaggcaacc
    54601 aacggtcact gtgcgatatg tgagacgatg gcgcaaaaac ggcaatatgc cagcctgacg
    54661 tcactcttcg cccagctttt cattgagctg gcggaatggc atagcccact ttatctggtc
    54721 atcgatgact atcatctgat cactaatcca gtgatccacg agtcaatgcg cttctttatt
    54781 cgccatcaac cagaaaatct caccctggtg gtgttgtcac gcaaccttcc gcaactgggc
    54841 attgccaatc tgcgtgttcg tgatcaactg ctggaaattg gcagtcagca actggcattt
    54901 acccatcagg aagcgaagca gttttttgat tgccgtctgt catcgccgat tgaagccgca
    54961 gaaagcagtc ggatttgcca tgacgtttcc ggttgggcga cggcactaca gctaatcgcc
    55021 ctctccgccc ggcagaatac ccactcagcc cataagtcgg cacgccgcct ggcgggaatc
    55081 aatgccagcc atctttcgga ttatctggtc gatgaggttt tggataacgt cgatctcgca
    55141 acgcgccatt ttctgttgaa aagcgccatt ttgcgctcaa tgaacgatgc actcatcacc
    55201 cgtgtgaccg gcgaagaaaa cgggcaaatg cgcctcgaag agattgagcg tcaggggctg
    55261 tttttacagc ggatggatga taccggcgag tggttctgct atcacccgct gtttggcaac
    55321 ttcctgcgcc agcgctgcca gtgggaactg gcggcggagc tgccggaaat ccaccgtgcc
    55381 gccgcagaaa gctggatggc ccagggattt cccagcgaag cgattcatca tgcgctggcg
    55441 gcaggcgatg cgctgatgct gcgcgatatt ctgcttaatc acgcctggag tttgttcaac
    55501 catagcgaac tgtcgctgct ggaagagtcg cttaaggccc tgccgtggga cagtttgctg
    55561 gaaaatccgc agttagtgtt attgcaggcg tggctaatgc aaagccaaca tcgctatggc
    55621 gaagttaaca ccctgctagc ccgtgctgaa catgaaatca aggacatcag agaaggcacc
    55681 atgcacgcag aatttaacgc tctgcgcgcc caggtggcga ttaacgatgg taatccggat
    55741 gaagcggaac ggctggcaaa actggcactg gaagagctgc cgccgggctg gttctatagc
    55801 cgcattgtgg caacctcggt gctgggtgaa gtgctgcact gcaaaggcga attgacccgc
    55861 tcactggcgc taatgcagca aaccgaacag atggcacgcc agcacgacgt ctggcactac
    55921 gccttatgga gtttaatcca gcaaagtgaa attctgtttg cccaagggtt cctgcaaacc
    55981 gcgtgggaaa cacaggaaaa agcgttccag ctgatcaacg agcaacatct ggaacagctg
    56041 ccgatgcatg agtttctggt gcgcatccga gcacaactgt tatgggcctg ggcacggctg
    56101 gatgaagccg aagcgtcggc gcgtagcggg attgaagtct tgtcgtctta tcagccacag
    56161 caacagcttc agtgcctggc aatgttgatt caatgctcgc tggcccgtgg tgatttagat
    56221 aacgcccgta gccagctgaa ccgtctggaa aacctgctgg ggaatggcaa atatcacagc
    56281 gactggatct ctaacgccaa caaagtccgg gtgatttact ggcaaatgac cggcgataaa
    56341 gccgccgctg ccaactggtt gcgtcatacg gctaaaccgg agtttgcgaa caaccacttc
    56401 ctgcaaggtc aatggcgcaa cattgcccgc gcacaaatct tgctgggcga gtttgaacct
    56461 gcggaaattg ttctcgaaga actcaatgaa aatgcccgca gtctgcggtt gatgagcgat
    56521 ctcaaccgta acctgttgct gcttaatcaa ctgtactggc aggccggacg taaaagtgac
    56581 gcccagcgcg tgttgctgga cgcattaaaa ctggcgaatc gcaccggatt tatcagccat
    56641 tttgtcatcg aaggcgaagc gatggcgcaa caactgcgcc agctgattca actcaatacg
    56701 ctgccggaac tggaacagca tcgcgcacag cgtattctgc gagaaatcaa tcaacatcat
    56761 cggcataaat tcgcccattt cgatgagaat ttcgttgaac gtctgctgaa tcatccggaa
    56821 gtgccagaac tgatccgcac cagcccgttg acccaacgtg aatggcaggt cctggggctg
    56881 atttactccg gttacagcaa tgagcaaata gcgggtgaac tggaagtggc ggcaaccacc
    56941 atcaagacgc atatccgcaa tctgtaccaa aaactcggcg tcgcccaccg tcaggctgcc
    57001 gtgcagcacg cgcagaaact gctgaagatg atgggttatg gggtgtgagt ttagccggat
    57061 aatgcattgg atccggttta catctttaca tcattcaata ctcacccgcg ttacgccatc
    57121 tgtttctatc aaaccaaacc gcaccggcaa gaaacgctcc accaccgcga tattggtcag
    57181 cagatggcat gaaggatggg cgaccttaaa ttctcccgcg cccgccagcg ccatcggcag
    57241 taccagttgg tcggcgagat attcccccac cgccgccggg cttgccaggt agcgtttcac
    57301 ctctttcact aactgcgcgg ctaccacctc ggcactgacg cgcttttcac cgacgacgaa
    57361 aaagcgttca gtgatatttt cactttcgac ttccagcgag acggtattac ccggcccctg
    57421 gtcgcgcggc aggttatgaa tattctgttc atgcagggaa aaactccccg ccagtgtagc
    57481 gatttcacgc tcagcaacat ggcgcggcac accagctaat agaacttctc cacgcatctg
    57541 cacaatgttc ccgcgctcgc caagttgcaa ggtgttaaac gatgccacgg gcgagacttc
    57601 cgttgccacc acgccgcctc cggcaggata aaaaccgtga cgtaacagcg tggtttgctg
    57661 atgaattcct attttcgcca gcagcggctc cagcacccgg cggataaaat ccgcaggcgg
    57721 ggccgacggg ttatcggtgc ctccgctcac ttcaacacgc gaaggtccat cggcaaacca
    57781 cagcgcgggc agcaccgttt gcagcaccag cgtacagctt ccggcactac cgatagcaaa
    57841 gcggtactcg ccgccgcgca cggtgccagg ccggaagacc agacgctgcg accccagctc
    57901 cgcgccttcc accgttgccc tacaaatttc cgcagccgct tttaccgcgg tcagatgctg
    57961 gcgcaacagc cccggtttcg cccgcccggc acgaatgctg gtgatggtaa atggctggcc
    58021 ggttatcatc gacaggctca gcgccgagcg caggatctgc ccgccacctt cgccctgtgc
    58081 gccatccagc gcaatcatcc ttttcatcat ttatcctttt acgcacacca cctgacgcag
    58141 ggtatagata acttccacca gatcgctttg tgccgccatc accgcatcaa tatctttata
    58201 cgccatcggg atttcgtcga tcacttcggc atctttacgg cattccacat gcgcggtggc
    58261 acgaatttga tcttccacgc tgaacagttt tttcgcttta gtacggctca ttacccgccc
    58321 ggcaccgtgg ctgcacgaac agaacgactc ttcatttccc agcccacgga cgataaagct
    58381 ttttgctccc atcgaaccgg gaataattcc atattgacca gcacgcgcag acaccgcgcc
    58441 tttacgcgtc acgtagatct cttcaccaaa gtgctgttct ttttgcacat agttgtggtg
    58501 acagttgatc tcttccatcg ccagcgtttg tggctgtctg accgttttct gcgtaatgct
    58561 ctgcaacgcc gttaccacgt tttccatcat cgcatcgcgg ttaaggctgg cgaaaagctg
    58621 cgcccaggcc acggctctta ggtaatcatc aaagtattcc gtaccttcca taaagtacgc
    58681 caggtcgcgc gatggcaacg tttcaagctg gtcctgcatc tctttttgtg ccaaatcgat
    58741 aaagtaagtc ccgatggcgt taccaattcc gcgtgaaccg gagtgcagca taatccacac
    58801 ctggtctgac tcatcaaggc agatttcaat aaagtggtta cccgttccca gcgttcccag
    58861 gtgtttatag ttgttagtgt taaggaaacg cggatatttt tgcgttaacc actgataacc
    58921 ggcttcaagc tcagcccatt tcgcatcgac gttaacaggc gggttttccc atgcgccttt
    58981 atcacgttta caacggccag tggtacgccc gtgcggcacg gccatttcaa tcgcctgacg
    59041 cagctctgcc aggttttcag gcaggtcttc cgccgttaac gcggtacgca gcgcgttcat
    59101 tccacagcca atatccacgc ccaccgccgc cggaataatc gcccctttgg tcgggatcac
    59161 gctaccaatg gtggaacctt tacccaggtg tacatcaggc attaccgcaa tatgtttgaa
    59221 aataaacggc atcttcgccg tattaataag ttgctgacgc gcatcggctt ctaccggcac
    59281 gcctttggtc cacattttta ccggggcatt ttcagtggtc agtaattcgt aattcatttt
    59341 gtttttctct tttcgttgtt tgctgtcgtg ataattgcaa ccgttgtgcc agaaaattaa
    59401 ataagcagat taatttttta attcattgtt tttaaatagg ttaaatcttt acgtccgtaa
    59461 acggagattt tccacaaaac caattcaccg ataatgaaat atcgtctttt ataaggatat
    59521 ctaagatgcg taaaacagtg gcttttggct ttgtcggtac cgtgctggat tatgccggac
    59581 gcggcagtca gcgctggtcg aaatggcgtc cgacgctttg tttatgccag caagaatcgt
    59641 tagtcatcga tcggctggaa ttgttgcacg acacccgctc gcgctcgcta ttcgaaacgc
    59701 ttaaacgcga tatcgccagc gtttcgccag aaacagaagt cgtgggcgtt gagattgaac
    59761 tgcataaccc gtgggatttc gaagaggttt acgcctgcct gcatgatttc gcccgtggtt
    59821 acgagtttca gccagaaaaa gaagactatt taattcacat caccaccggc acccacgtcg
    59881 cgcagatttg ctggtttctg ctggcggaag cgcgttacct gcccgcccgg ctgatacaat
    59941 cttcacctcc gcgcaaaaaa gaacagccgc gcggcgcagg tgaagtgacg attatcgatc
    60001 tcgatttaag ccgttataac gccatcgcca gccgctttgc cgaggaacgc cagcaaacgc
    60061 ttgattttct taagtccggc attgccacgc gtaaccccca cttcaaccgc atgattgagc
    60121 agatcgaaaa agtggcgatc aaatcccgcg cgccgattct gcttaacggt ccaaccggcg
    60181 cgggcaagtc atttctggcg cgacgcatct tcgagttaaa acaggcgcgg catcagttta
    60241 gcggcgcgtt tgtggaagtg aactgcgcca ccctgcgcgg cgataccgcc atgtcgacgc
    60301 tgtttggtca tgtaaaaggc gcgtttaccg gggcgcggga atctcgtgaa ggtttattac
    60361 gcagcgccaa cggcggaatg ttgtttcttg atgagattgg cgaactgggc gcagacgaac
    60421 aagcaatgct gctaaaagcc attgaagaga aaacctttta cccgtttggc agcgatcgcc
    60481 aggtgagcag tgattttcag cttatcgccg gaacggtgcg cgatttgcgc cagctggttg
    60541 ccgaaggcaa atttcgcgaa gatctgtacg cgcggatcaa tctctggacc ttcaccctgc
    60601 cgggtctacg ccagcgccag gaagatattg aaccgaacct tgattatgaa gtggagcgcc
    60661 acgccacact cactggcgac agcgtgcgtt ttaacaccga agcgcggcgc gcctggttgg
    60721 cttttgcgac ctctccccag gcaacatggc gcggtaactt tcgcgaactt tctgccagcg
    60781 tcacgcggat ggccaccttt gccactagcg gacgcatcac tctggacgtg gttgaagatg
    60841 agataaaccg tctgcgctat aactggcagg agagccgccc ctccgcgctt acggcgttgc
    60901 tgggcgcaga ggcagaaaac atcgaccttt ttgacaggct gcaactggaa cacgtgatag
    60961 ctctctgtcg ccaggcaaag tcgctttccg ctgccggacg cctgcttttt gatgtttcgc
    61021 gccagggcaa agccagcgtc aatgacgcgg atcggctacg caaatacctg gcgcgttttg
    61081 gtctgacgtg ggaagccgtg caggatcagc acagctccag ttgaatatga tggtccgtca
    61141 gcacctgcat tacgcttact ggcggcgggg cgtcggtgta gacggcatct accatgctga
    61201 tgctgcccat attgaccatc gcgttacggc caaatttcga gtgatcgaca accagcataa
    61261 cgtggcgcga gttctcaata atggcgcgct tggtgcgaac ttcgtggtaa tcgaactcca
    61321 gcagcgagcc gtcgctatcg atgccgctta tccccagaat gccgaaatca aggcggaact
    61381 gggagataaa atcgagcgtc gcttcgccaa tgatcccgcc atcgcggctg cgtaattcgc
    61441 caccggcgag aataatgcgg aaatcttctt ttaccatcaa cgtgttagca acattgagat
    61501 tgttggtgac aatacgcaaa ttgctgtgat taagcagcgc gtgcgccacc gcttccggcg
    61561 tggtgccgat atcgataaac agtgtcgagc cgttggggat ttgctccgcc actttgcggg
    61621 caatcctctc tttttcttcg gtctgggtgg ctttgcgatc gtgccacggc gtgttaaccg
    61681 aactggaagg cagcgccgca ccgccatggt gacgcaggat caggttttgc tccgccagct
    61741 cattgaggtc gcggcgaata gtctgcgggc tgacggagaa atgctctacc agctcttcag
    61801 tactgacata accctgctgt ttaaccagtt cgataatacc gttgtgacgt tgtgtttgtt
    61861 tcatttataa atccctggaa ttattttcgt tttcgcgcat tgagcgaatc aacaaaagcc
    61921 atcgctaaac ccacggctaa cccggcgatg tgtgctccgt tcgccatcga catcccaaac
    61981 aaatcaaacc atccggcgac aatccagatc agcgcaaaga taattaaccc acgttgcagg
    62041 taaatgccac tttgcggatc gcgttcacca cgtagccaga cgtagcccat cagcgcatac
    62101 accacgccag aaagcccgcc aaaccacggc ccgctgaatt tttgctgcac atagccgctt
    62161 aacagggcgc taatgagagt aataacaatt agcttaccgc taccgaggcg tttttccacc
    62221 gcaccgccga gataccacca ccagagcagg ttaaagagga tatgcatcag cgagaagtgc
    62281 attaacgcgt gggtgaagta acgccagaac tcaaatttca gtgttggatc gaatggccag
    62341 gccagccata acatcacttc ctgatcgccg agaatttgca tggcgataaa caccaccacg
    62401 caggcgatca tcaccaccca ggttaccgga cctgcgcgtt cacgcaaggc ggcaaagaaa
    62461 ggataacggc gataatgcag gccactgccg gtatggcctg cctgccagct ggccgccaga
    62521 taacgcggat ctgccgggtt ttcgagaaaa cgcgccagct ccgcccgtac gcgctcggcc
    62581 tgggactcat ccgccagcca gacatcgctt tggttatgtt gttgaatcgt gaggataaca
    62641 ccctgcgtcg ccatgtaatc aacaaacgcc tgcgccacgc gggggttagc aaaagaggta
    62701 atcatcaaca tcgttgctgt cgcttattcc acacaaaagg ggacagtata aagcgttacg
    62761 cgccgtacgc cacctctgcg ggaaactgac gttgccaggc ttcaaagccg ccgtcaatgc
    62821 tatagaccac atcgtagccc tgttgcagca gatactgcgc cgcgcctttg ctgctattgc
    62881 cgtgataaca catcaccatc accggagtgt caaagtcgtt atcacgcata aacgcgccca
    62941 gcgtgtcgtt ggttaaatgg aaagcctgca ccgcatgccc catagcgaaa ctctgtggat
    63001 cgcgaatatc gaccagcacc gcctcttttt cctgcaactt ctggtgcgcg tcggcaacgt
    63061 taatacattc gaactgatcc atgcgtctct ctttctttac aaacaagtgg gcaaatttac
    63121 cgcacagttt acgtcgaagc ggcagataaa cgccataatg ttatacatat cactctaaaa
    63181 tgttttttca atgttaccta aagcgcgatt ctttgctaat atgttcgata acgaacattt
    63241 atgagcttta acgaaagtga atgagggcag catggaaacc aaagatctga ttgtgatagg
    63301 tggcggcatc aatggtgctg gtatcgcggc agacgccgct ggacgcggtt tatccgtgct
    63361 gatgctggag gcgcaggatc tcgcttgcgc gacctcttcc gccagttcaa aactcattca
    63421 cggtggcctg cgctaccttg agcactatga attccgcctg gtcagcgagg cgctggctga
    63481 acgtgaagtg ctgctgaaaa tggctccgca tatcgccttc ccgatgcgtt ttcgcctgcc
    63541 acatcgtccg catctgcgcc cggcgtggat gattcggatt ggtctgttta tgtacgatca
    63601 tctgggtaaa cgcaccagcc tgccgggatc aaccggtttg cgttttggcg caaactcagt
    63661 gttaaaaccg gaaattaagc gcggattcga atattctgac tgttgggtag acgacgcccg
    63721 tctggtactc gccaacgccc agatggtggt gcgtaaaggc ggcgaagtgc ttactcggac
    63781 tcgcgccacc tctgctcgcc gcgaaaacgg cctgtggatt gtggaagcgg aagatatcga
    63841 taccggcaaa aaatatatct ggcaagcgcg cggcctggtt aacgccaccg gcccgtgggt
    63901 gaaacagttc ttcgacgacg ggatgcatct gccttcgcct tatggcattc gcctgatcaa
    63961 aggcagccat attgtggtgc cgcgcgtgca tacccaaaag caggcctaca ttctgcaaaa
    64021 cgaagataaa cgcattgtgt tcgtgatccc gtggatggac gagttttcca tcatcggcac
    64081 caccgatgtg gaatacaaag gcgatccaaa agcggtgaag attgaagaga gtgaaatcaa
    64141 ctacctgctg aaagtgtata acgcgcactt taaaaagcag ctaagccgtg acgatatcgt
    64201 ctggacctac tccggtgtgc gtccgctgtg tgatgatgag tccgactcgc cgcaagccat
    64261 tacccgtgat tacacccttg atatccatga tgaaaacggc aaagcaccgc tgctgtcggt
    64321 attcggcggt aagctgacca cctaccgcaa actggcggaa catgcgctgg aaaaactgac
    64381 gccgtattat cagggcattg gcccggcgtg gacgaaagag agcgtgctgc cgggtggtgc
    64441 cattgaaggc gaccgcgacg attacgccgc tcgcctgcgc cgccgttacc cgttcctgac
    64501 tgaatcgctg gcgcgtcatt acgcacgcac ttacggcagc aacagcgagc tgctgctcgg
    64561 caatgcgggg gcgataagcg acctcgggga ggatttcggt catgagttct acgaagcgga
    64621 actgaaatac ctggtggatc acgaatgggt ccgccgcacc gacgatgccc tttggcgtcg
    64681 cacaaaacaa ggcatgtggc tgaatgcgga tcaacaatct cgtgtgagtc agtggctggt
    64741 ggaatatacg cagcagaagt tgtcgctggc gtcgtaagga tgatgcccgg ttgaagtgca
    64801 accgggctat ttggattcct tagactattc attgtaaata attgaataac ggcccctgag
    64861 ctaaaatcgc caaacttaag cacgttaccc aattgcccca cttcttcctc tggtttctat
    64921 tttttctgca ccaatggcaa taatatccca atgcaaaacc aagctgtgca ctaatcgggc
    64981 cgacaaaatc agtccaaggc tgcggccaaa aaggggaaaa attcagggga ggccagacaa
    65041 acgtcagaaa gaaatttcgg atattttcca gcaacgctga tttctctgga gaaatataaa
    65101 gaatgaaatt cgagagaatt aaccagaaat agaccggcga aaagaccagc cagcaatgca
    65161 gtctgttttt taattcagga ggcgttctgc gggagaattg ccaaccgatg ccagccatta
    65221 cactgaaaaa aagtgcatat tcaaccatta actcaagttg taattcctga agagaaatac
    65281 gcacaaccag gagcggaaag gagaatatta tttctgccag aaaagttaac gtgaatataa
    65341 gtacggctaa gacaataacc gtcggccata ccaataatgg cacgataaca aaaccgagaa
    65401 ttacaggggg aatataaagc cggaatttaa tcatttttat tttcctggtg attcggatga
    65461 tgcgtcatac atcgcgcata aacactcatc aattatccag tcatcttccc agacctgata
    65521 ttctgtcatt ggttcgggct gttttagcgg gttctcaatc gcttgccgcg ctctttcttt
    65581 cagtaaagga tgattatttc tagcccaggc attgatttgg gtggtaatga cgttatcgat
    65641 atcgtcctgg ttatctctga tataatcctc acaatatctg ttcaataaac aggcaagaga
    65701 aacggtcgac caaaagccgg gaactgaatt aatggcatcc agcaatggcg caagagcgat
    65761 atcggcacgg aaaaacattt ccagcatata ctgtaattcg acagcttcat cgccggatac
    65821 ccaatcagtc atatactggc aggcaaatcg ttgcaaaatt ttccattcat cctcacgcca
    65881 attttcttta ctggcaaggt ttatacgccg tagagaaaat acttcgtgaa tattgtcaaa
    65941 ctgcccctgt gcaacaaatt ccagtaaacg cggcagaaaa tagcggacct catcgctatt
    66001 ttgcggatca ggccctgggc tactattcca tgcattgatt aaggaatacg agatcgctcg
    66061 taacgatgta ctccgtaata ccttttgttc ctgctgactc aggcaatatt cacaacaaac
    66121 cacaaatttc tgcggcaccg gataacgacg aaaaatatga taaatctgct caattaatgc
    66181 ctgcatggcg gggctgggtt gcataattac cccctcgccc gctgatcgcg tgtaaacggt
    66241 tgatagacaa aacgagcatt cgccgcgttc aggcgaataa gggcgctacg cgaaagggaa
    66301 aagctggggc gaatgcaact attgcagtct cgacagcttt cctctgcgca attttccact
    66361 gagtaatgac gcgtgtagag tttcagttcg gcctgcttat cgcgaaatcc gcgtaaactg
    66421 ttattgttat gaaatttcca ggcatctttt aagacctgaa agatatagac atcctcaatc
    66481 caggagtcac attttttaag cgggcgcttt gctattatca cccgctcatc cggatttagc
    66541 atcgccgtaa attgtacggt gacgtcattt gtcgtgttca ggtcacattg aacatctggt
    66601 acatcactga tataggggtc aaatccaaaa tcagcaccac aggcacaaag acggctaatg
    66661 gtggcggtat cgagggaaaa tcccggccat accttgctgg aggttaagcc aatatttaat
    66721 gtgacattat atcgaagcaa tccctcaaga ccgtcagcac cgacgaactt ttccccttca
    66781 tccagggcct ggttaatgag ttgctgaaca atgccttcat cccagtatgc cgatttgcag
    66841 ttggcaatcg taatatccac gccagtgaat ggatcagtac cgacaaggct tgcaaataat
    66901 gtattaacta attccatttt tattatccgc cttaatgcaa cgttttatac atcggcacat
    66961 aacctacatc ttccaccagg ctctgcccct gcggcgttaa aaaccactcc accaattttt
    67021 gtgtttctga cgtcatattt tcccgcgtta ccataaaggc atcgacgata tagggatatt
    67081 tgccgttgcg aatgttttcg gcagtcggtg caataccgtt aatcgctagc agttttatat
    67141 ttttatcggc gttcatttgt gttgcgtaat aacggaaggt gtaacctatt gcgttgtttg
    67201 tattacggta ttcggcaacg actttaatca ttccctccat catacttgcc acttctgttt
    67261 cctgcggcga gatcatgcgg acatttttca tgacctggga ttgcatcacc gtctggctac
    67321 cagagtcttc cgggcgttgc caggtctgga tctcctgatc gttaccgcca accgtgcgcc
    67381 agttggtaat tgcaccactg aagatgtcac gcacttgttg ttcggtcagg gaattaaccg
    67441 ggttatctac attgacgatg aaaacaaacg cttcacgggc aaaaggcgtg taaatcaaag
    67501 tgacgcccga ttcctccgcg cgttttttct gcccaccgga aggttgagcc acaaagataa
    67561 tatcggcatt acctttaaca atcttgttat atgcttcggg agtacgagag ttcgccagat
    67621 attcccattc gtgaaaatct tccggcaaaa cgcttagtgc ataaaaggca gaggcataaa
    67681 tggggtacgc cgccgttgcg ccatcaagtc gcggccagtt ttgcgtgaac tgaatttgcg
    67741 gtttaccacg cagtggtgtc agttgattat tgagtttatc gggtcgccag gcccaggtat
    67801 caatattttc acgcacaccg acgccgggat taagctgttt atataaataa gcctggtaac
    67861 cggcgacaaa accaagcatg agaaggataa acaagagaga attacggcaa cgtaacccgg
    67921 acgtgcccgt taaaggatat ctggtcggcc agccgtaccc cagcgaaaaa ctgatatgcg
    67981 cgccaacagg tataatgact aaccaccagt actcaccacc gactaatgag gctaacaaaa
    68041 cgcccagcca ggggagcata agatcagcca accaacccgc tcccatctgg cgaaattgat
    68101 aatctgccag atgcagcgcg attatccaga cccccagggt taataatgcg ggtactaaaa
    68161 aaagacattg tcgccagacg gctatttctc ttttttctgg tgcactatcg tccgcccaca
    68221 ctcgccccga gaaaaatagc attaatgcgc ccagcgccag cataaaaatg ttgagcagaa
    68281 ggtaaattgt tggcgtgata aagatattac aaacttcaat aataccggca agtccgacac
    68341 ccagcatggc aataaccgcc gccaaaaact gcgccagaat ggggatgccg aaaaaagtca
    68401 ttaccagcga ggtcaaaatc cattttctgt tttgcattat tctttccatt ctttctgaat
    68461 ggcgaaatta tactccccga gtccccttgc cccttctgga cacttttccg aaatgatggc
    68521 gaaaaaaacg ggaccctttg gccccgttct atttattagt gaaattacaa tctcaccgga
    68581 tcaatatgcc agatatgatc ggcgtactct ttgatagtac ggtcagaaga gaagtagccc
    68641 atattggcaa tgttcagcat cgcttttgcg gtccactctt cctgaagctc gtagagttcg
    68701 tcgactttat cctgacaatc gacatagctg cgataatccg ccagaacctg atagtgatcg
    68761 ccgaagttga tcagcgaatc aaccagatcg cgatagcgac ccggatcttc cggactgaat
    68821 acaccgctgc cgatttgcgt cagcacctga tgcagctcct catctttctc gtagtattca
    68881 cgcggtttgt agccctgacg acgcagttct tccacttctt ccgcagtgtt accaaagata
    68941 aagatattgt cagcaccgac atgatccagc atctcgacat tcgcaccgtc caacgtaccg
    69001 atagtcagcg caccgttaag cgcaaacttc atgttactgg tgccggaagc ttccgtcccc
    69061 gccagcgaaa tctgttcaga cagatcggcc gccggaatga tcaactgcgc caggctaacg
    69121 ctgtagttcg ggatgaacac gactttcagc ttgtcgccaa tctgcggatc gttgttgatc
    69181 actttcgcta cgtcattgat caaatgaata atgtgcttcg ccatgtaata ggccgaagcc
    69241 gccttaccgc caaaaatatt cacgcgcggt acccacttcg catccgggtc ggccttgatg
    69301 cggttatagc gggtaatcac atgcaacaca ttcatcaatt gacgtttgta ttcgtgaata
    69361 cgtttgattt gtacatcgaa caacgccttt ggattcacca ccacattcag ctgctgggcg
    69421 atatactctg ccagacgctt tttgttctcc agcttcgcct gatgcacagc gtgattaacc
    69481 attgggaaat cacagtgttg ttgcagctca ttaagcaggc taaggtcggt gcgccagtta
    69541 cggcccaggt gttcgtccag cacggctgaa agcgatgggt tcgctaccgc tagccagcga
    69601 cgcggcgtca caccgttggt gacgttggtg aaacgacccg ggaagatttt cgcaaagtcg
    69661 gcaaacaacg attgcaccat cagattagag tgcagttccg atacaccgtt aactttgtgg
    69721 ctcacaacaa ccgccagcca ggccatacgc acacgacgac cgttggattc atcaatgatc
    69781 gacgcccgtc ccagcagatc ggtatcgttc ggatactgtt cctgcaaggt tttcaggaaa
    69841 tagtcgttga tttcaaagat gatctgcagg tgacgcggca gaattttacc cagcatatca
    69901 accggccagg tttccagcgc ctcgctcatc agcgtgtggt tagtgtagga gaagacctga
    69961 caacacacct caaacgcgtc gtcccagcta aattggtgct catcgatcag cagacgcatc
    70021 atctcaggaa tcgacagtac cggatgggta tcattgagat gaatcgcgat tttatccgcc
    70081 aggttatcgt aggttttatg caactgataa tggcggctta aaatgtcctg aatggtcgag
    70141 gaaaccagga agtattcctg acgcaggcgc agctcacgcc cggagtaggt ggagtcatcc
    70201 ggatacagta cgcgagatac gttctcggag tggtttttat cttccactgc cgcgaagtag
    70261 tcaccctggt tgaatttacc gaggttaatt tcgctactgg cttgcgcact ccacaaacgc
    70321 aacgtgttgg tcgcgtcggt atcgtaacca gggattatct gatcgtaagc gactcccaga
    70381 atctcttcgg tttcaatcca gcgcgttttt ttaccttcct gctgaatgcg accaccaaaa
    70441 cggactttat agcgcgtgtt gtggcgtttg aattcccacg ggttaccgta ttccagccag
    70501 tagtctggcg actctttctg gctaccgtta acgatgttct gcttgaacat accgtagtca
    70561 tagcggatgc cgtaaccgcg ccccggcaac cctaacgtcg ccagagaatc aaggaagcaa
    70621 gccgccagac gtcccaggcc accgttaccg aggcccggat cattttcttc atcaatcagc
    70681 tcttcgagat ttaaccccat cgcttccagt gcgccctgta catcttcgta aattcctagc
    70741 gacaacatgg cgttggagag cgtacggcca atcaaaaact ccatcgacag gtagtaaacc
    70801 tgacgagttt cttgcgacaa ctgggcacgg tttgaacgta accagcgctc cacgagacga
    70861 tcgcgcacag caaataacgt tgcgttcagc cattcatgtt tattggcgac gaccgggtcc
    70921 tttccaatcg taaacatcag cttgtaagcg atagagtgct taagagcttc tacgctaagc
    70981 gtgggcgatg aatatgtaaa cggagcattc atataggcgt ttcctgaaaa ctatttcaag
    71041 cgatagtaaa gctcacggta cgacttcgcc gcgacctgcc agctaaaatc cattgccata
    71101 gcctgacgtt gcacaaaccg ccacagtgaa ggacgggacc acagtacaaa agcacgccga
    71161 atagcccgta acagcgacca ggcattacta tcttcaaaga caaacccact ggcgacgcca
    71221 tctgcaaggt tctcaagaga acagtcagaa accgtatcag caagcccacc ggtgcgccgc
    71281 actaacggca gcgtaccgta cttcaatcca taaagttgcg ttaagccgca cggttcaaaa
    71341 cggctgggca ccagaatgac gtccgcgccg cccataatgc gatgcgaaaa tgcttcgtga
    71401 tagccaatct gaacgcccac ctggccgggg tattccgctg ccgccgcaag gaaaccttcc
    71461 tgcagcaccg gatcgcccgc gccgagtagc gccagctgcc cgccctgctc cagaagaccc
    71521 ggtaaggctt ccagcaccag gtcgagacct ttctggctgg tcagacggct caccactgca
    71581 aaaagcggca ctttatcgtc aaccttaagc cccattgcga tttgtaactg gcgcttattt
    71641 tccgctttat cttccaacgt atcgcgggtg taacgcgagg ccaacagtaa gtccgtctct
    71701 ggactccaga ttttctcgtc cacgccgttc agtacgccgg aaagacgccc ttcacggtga
    71761 cgctgttgca acagaccttc cataccgtag gcaaactgcg gttcggtgat ctcgcgagcg
    71821 taggttggac tgaccgccgt aatgtgatcg gcatagtaca gaccggcctt caggaaagag
    71881 atttgtccgt tgaattccag cccatgaata ttaaagaatg accatggcaa ttggatgtca
    71941 ttcatatgat gtgcataaaa catgccttga taggccaggt tgtgcacagt aaacaccgac
    72001 ttcgccggac gcccgcgcgc cgccagatac gcaggcgcaa ggcctgcatg ccagtcgtgc
    72061 gcatgcacca catcaggacg ccagaatggg tcaagcccgc tggccatttc tgccccaacc
    72121 caccccagca gcgcaaaacg caatacgttg tcggtatagg caaataagtt ggtatcgtga
    72181 tacgggcttc ccggacgatc atagagatgc ggcgcgtcaa tcaggtatat gccaaccccg
    72241 ttgtaatgac cgaacaacag cgtgatatgt ccggcgaagg tatcacgacg ggatactacc
    72301 tgcgcatcgg taacgccacg gcgaatatcg ggaaatgcag gcaacagtac gcgagcgtca
    72361 acgccgtctg cgatttgtgc tgcgggtaat gccccaataa catcagccag accgccggtt
    72421 ttaagcagcg ggaacatctc tgaacataca tgtaaaacct gcattatcgc tcctgtttat
    72481 gccctaactt ccgtagcatt tcgcgcgtta ccagcacgat gccttcttct gaacgataga
    72541 aacgacgtgc atcttcctct gcgttttcac caatcaccat gccttccgga ataacacaag
    72601 cacgatcgat gacgcagcgg cgcagacggc acgagcgacc tacccatact tccggtaaca
    72661 atacggcgga atcaatgttg cagaatgaat tcacgcgaac gcgcgagaac agaacggact
    72721 gcaccaccac cgaaccggag atcacacagc cgccggatac cagtgagtta agggtcatcc
    72781 cgtggctacc ggagcgatcc tgcacgaatt tcgctggcgg taatgattca ttgtaggtgc
    72841 gaattggcca attgcgatcg tacatatcca gttccggcac cacagaggcc agatcgaggt
    72901 tcgctttcca gtaagcttcc agcgtaccca catcgcgcca gtacggctcg gcatccgggt
    72961 cggattgtac gcaagagagc gggaacgggt gcgcataggc cagaccggct tcggtgatct
    73021 tgggaatcaa atctttgcca aagtcgtggc tggagttctc atcacgatcg tcttcttcca
    73081 gcagttcata cagatagtcg gcgtcaaaga cgtagatacc catactcgcc agagatttgc
    73141 tcggatcgtt cggcattgac ggtgggttag caggtttttc aacgaattcg ataattttat
    73201 cgttctcatc aaccgccata acgccaaatg cggaggcttc ttcaatcggt actggcatac
    73261 aagcaacggt gcaacgtgcg cctttttcga cgtgatcgat aagcatacgc gagtagtctt
    73321 gcttgtagat atggtcgccc gccaggatca ccacgtattc cgctttataa cggcggataa
    73381 tgtcgaggtt ttgggtgacc gcatctgcgg tgccgcgata ccagttttcc cctttcattc
    73441 tctgctgtgc tggcagcaga tcgacaaact cgttcatttc ttcattgaag aatgaccagc
    73501 cgcgctgaat gtgctgcacc agagtgtggg actggtactg ggtgatcacg cccatacgac
    73561 ggatcccgga gttgatgcag ttagacagcg caaagtcgat aatgcggaac ttaccgccga
    73621 agtgtacggc cggttttgct cgcttattgg ttaaatcctt caggcgggta ccacgtcctc
    73681 ccgccagtat cagggcaaca gatttcaatg gcagctggcg cgccaacatt aagtgatcgt
    73741 tcttctctaa actaaccatg actaactcct tttttatcat ctctggaaca cacacaatcc
    73801 gtgtgcaggt ccctgccaga cagccgtaat cactgggtta tcctctccag cgaatggggg
    73861 aatggcgtgc cactccccag caggtaaaac aatctctgtt acctcaagcg tggcgttaat
    73921 tgcgatcaaa aagcgatccg agagcagaat ttgcagctgt ttcggcccgt tttgccactc
    73981 atccgtgctt aaaggttgag catatcgatt tagccaacgg acattgccgt cgccttcttc
    74041 ccaccagcga ttctccacca aagcgggaat gcgcttgcgc agatggatta acgcggcggt
    74101 aaatgcggtt aaaccactgc ttgcctgcga ccagtccaac caggttaatt ggttatcctg
    74161 acagtaggca ttgttattgc catgctggct gtgaccatgt tcgtcaccgg ccagtaacat
    74221 cggcgtaccc tgggagagca acaacgttgt taacagggcg tgaatgctgt cgcgccgccg
    74281 ttcaaccagg tcaagagaac cgcctaaccc ttctttacca tgattgttac tgtaattgtt
    74341 gttggtcccg tcgcgatttt cttctccgtt tgcttcattg tgtttatggt tgaagcaaac
    74401 gcagtcgcga agcgtaaaac cgtcatgcgc ggtgacgaga ttaatcgcgg cactcggcag
    74461 acgaccatta cgtttaaaaa catcgctgga ggcagcaaaa cgcccggcaa acgcccccag
    74521 aggcaaatca taatgtagcc agaaacgacg ggcagcatcg cggaaatgat cgttccactc
    74581 ggcaaacagc ggcgggaaat ttcccacctg ataaccacca ggagcgatat cccacggttc
    74641 agcaattaac ttcacctgcg agagcaccgg gcagttctgg atagcggtaa acaacggcgc
    74701 atcctgacgg aactctggcg tacggcccat gactgccgcc agatcaaagc ggaaaccatc
    74761 gacgtggcag gtttctaccc aataacgcag gcaggcgctg gcataatcca ccaccgccgg
    74821 atgactcaaa ttgagcgtgt tgccgcaacc ggtccagttg tgataatcgc cgtcttctct
    74881 tatccaataa tagctacggt tatcgatccc acgcagcgag aataacgggc cgtcgaggtc
    74941 cagttccgca ctatggttga gcacgatatc aagaatgact tcgatacccg ctttatgcag
    75001 tgctttgatt gcatcgcgaa actcatccag cgccgtttct ggcgagcagg catacgccgg
    75061 atgcagcgca aacatcgcca ccgggttgta accccagtag ttacttagcc ccatgcgttg
    75121 cagacgtggt tcactggcaa actgcgccac tggcagcagt tccagcgcgg taatgcccaa
    75181 ttgtttcaaa tagttgatca tcaccggatg cccgagggct ttataagtgc cacggatctc
    75241 gaccgggatc tccgggtgca agtacgttaa tcctttgaca tgggcttcat aaatgatggt
    75301 gctgccccac ggcgtgcgcg gcggggcatc atcttcccag tcatagtgat caaccaccac
    75361 tacgcatttc ggcgcaatgg cggcgttgtc gcgatagtca ggttcattat gaccggcgtg
    75421 cagcagcggg ttatctttaa actccccctc aatttgccgc gcgcaaggat caatcaacaa
    75481 cttcgccggg ttaaagcgat gcccctcggc gggttgccag gggccatgaa cgcgataacc
    75541 ataacgcaaa cccgggcgcg catccggcag ataaccgtgc caaatgtcgc cactgtgccc
    75601 tggcaagtca tagcgatgtt cctggccatt ggcgtcaaag acacacagtt ctacccgctc
    75661 ggcatgagcg gagaaaagtg tgaagttgac gccctgaccg tcgtaatgcg cgccgagggg
    75721 agcgggtttg ccaatggcga gttgtgtcat tctgcctccc gaaccagcca gatagtggcc
    75781 agcggtggta gcgtcaggct tagtgaatgc tgacgaccgt ggctggcaat ctcatcgctg
    75841 tgtaccgtgc cgccattgcc tgcattactg ccgtgatagt gcatggaatc ggtattgagg
    75901 atttcacgcc atttgcccgg ctggtttatg ccgaagcgat aatcatgacg cggcaccggc
    75961 gtaaagttac tggcaacgat gatttcgtta ccctctttat cgcgacgcac aaagatcagc
    76021 accgagcgtt ctttgtcatc caccaccagc cattcaaagc cgtacgggtc aaaatccagt
    76081 tcatgcattg ctttatggtg gcggtaggtg aggttcagat cgcgcaccag acgctggaca
    76141 ccgtggtgcc agttatcgcc gccttccaac agatgccagt cgaggctggc gtcatggttc
    76201 cactcgcggc cctgggcaaa ttcgttaccc atgaacagta gtttcttgcc cgggaatgcc
    76261 cacatccagc catagtaggc gcgcaggttc gcgaatttct gccatgcgtc gcccggcatg
    76321 cggtcgagaa tcgatttttt accgtggacc acttcatcat gcgacaacgg caggacgaag
    76381 ttttcagtgt agttgtagag aatcccgaag gtcagtttat cgtgatgata ctgacgataa
    76441 accgggtcga gcttcatgta gtccagggtg tcatgcatcc agccgaggtt ccacttgtac
    76501 cagaagccca gaccgcccat atcctgcgga cgagaaacgc cagggaaatc ggtagactcc
    76561 tcagccattg tcaccgcacc ggaaacctgc tcaccaagaa tacggttggt attacgcaag
    76621 aattcaatcg cttcaagatt ctcgcgcccg ccaaattcgt tcgggatcca ctccccctct
    76681 ttacggctgt agtcgcgata aatcattgac gccaccgcat cgacgcgcag cgcatcaata
    76741 ccaaaacgtt caatccagta aagcgcgtta ccgacgagga agttactgac ttcacggcga
    76801 ccatagttgt agatcagcgt gttccagtcc tgatgatagc cttcacgcgg atcgctgtgt
    76861 tcatacaagt tcgtgccatc aaattcggca agcgcaaagt catcagtcgg gaagtggcct
    76921 ggcacccagt cgagaatcac gttcagacca gctgcgtgtg cggcatcaat gaaataacgg
    76981 aagtcgtcgc gagtaccaaa acggcgggtt ggtgcataca ggccggttgg ctgataaccc
    77041 caactgccat cgaagggatg ctcgttaatg ggcagtagtt cgaggtgggt aaagcccatc
    77101 catttagcat aaggcaccag ttgatcggcc agctcgcggt agctcaacca gaaattgttg
    77161 tcggtgtggc gacgccagga acccaggtga acttcataaa tagagattgg cgcatcaaac
    77221 tgattcgctt ttttgcgctc ttcagtctgt acaacctttt ccggcagccc gcaaataaga
    77281 gacgcggttt ccgggcgcat ttgcgcttcg aaggcataag ggtcggactt cagacgcaag
    77341 ttgccattgg catcaatcat ctcgtattta tagagctgac cgttatgcgc cccagggata
    77401 aacagttccc agatgccgct ctctttacgc aggcgcatcg ggtgacggcg accgtcccag
    77461 tagttgaatt gcccaaccac cgagacccga cgggcgtttg gagcccagac agagaaacgc
    77521 gtacctgtga cgccatccat agtatctgca tgcgcgccta aggtttcata cgggcgcagg
    77581 tgagtacctt cagataatag ccaggcatcc atttcctgga ttagcggacc aaaacggtaa
    77641 ggatcatcaa tcaggttttg ctgaccatgc cagacaacag ccaactgata gcggaaaaaa
    77701 ttcttacgtc gcggaatgac gccgctaaag aatccccgtg agtcgagaca ctccagtttt
    77761 gcgagtttgc gcccggtttt cggttcaatc acccacacat cggtagcgtc gggtaaaagg
    77821 gcacggactt ccagtcccgc ggtggtttta tgcattccca gtacggaaaa aggatccgca
    77881 aaatggcctg caattagcgc gttaatcacg tctctatcga tacgatcgga catgcttgtc
    77941 ttcctgtttt attgtgtcac cccatccaat tggatttttg acttctggtt gtgacatttt
    78001 tttgacctga acggcgcagc actctgtgca tcctctctgc gtcgtcctca cttcaggtaa
    78061 ggctgtgaat actcatgtat tcagccaccc ttaaagaata gccaatgctc tatttaactc
    78121 ccggtaaatc atgaaacatc tgcgcttact cctgtattac gcactaacag gggcggcatc
    78181 gcgccccaga tttaatgaat aaagattacg ccagttgacg aagcatccga cgcagcggct
    78241 ccgcggcccc ccacagcagc tggtcgccca cggtaaaggc tgacaggaac tctggtccca
    78301 tattcagctt acgcaggcgg cctaccggcg tggtcagcgt gccggtaacg gcagctgggg
    78361 ttagctcacg catagtgatt tcccgatcgt tcggaacgac tttcgcccac ggattgtgcg
    78421 cagccagcag ttcttccacg gtcggaatag acacatcttt tttcaattta atagtgaatg
    78481 cctggctgtg gcagcgcaat gccccgacac gcacacataa accatctacc ggaattacgg
    78541 aagatgtgtt gaggatcttg ttggtttccg cctgcccttt ccactcttcg cggctctgac
    78601 cgttatcgag ctgtttgtcg atccacggaa tcaggctacc cgccagcggc acgccaaagt
    78661 tatccaccgg cagctcaccg ctacgggtta aggttgtgac tttgcgttcg atatcgagaa
    78721 tagcagagga cggggtcgcg agttcatctg ccacatggcc atacagatgg cccatctggg
    78781 ttaataactc acgcatatgt cgcgcaccac cgccggaagc ggcctggtag gttgcaacgg
    78841 acacccaatc aacaagatca ttggcgaata aaccacccaa cgacatcaac atcaggctta
    78901 cggtacagtt accgccaaca aaagtcctga tgccattatt taatccgtcg gtaatgacgt
    78961 cctgattgac ggggtcaaga atgatgatgg cgtcatcttt catgcgcaga gacgatgctg
    79021 cgtcaatcca gtaaccttgc catccgcttt cacgaagctt tggatagatt tcgttggtat
    79081 aatcgccgcc ctgacaggtc acaatgatat cgagggcctt tagcgcctcc agatcaaagg
    79141 catcctgaag tgtgccagtg gttccgccaa aagacggcgc agcctggcca agctgagaag
    79201 tagaaaagaa gacagggcga atggcgtcga agtcgcgctc ttcaaccatg cgttgcatga
    79261 gaacggagcc gaccataccg cgccagccga taaaaccaac atttttcata agcgtttttt
    79321 tcctgcaaag atgtgtgctg tataaatgtg ccggtctcct cttggcacat ctttcaccat
    79381 acaaaaagca gccaaagtcg caagtgaaat taatcaatga tagcgaagcc atcagtaatg
    79441 cgacttatcc tgctttgtta gcacgcagaa agtccgcggc aattatcagg gaatttgagt
    79501 tatgaatgaa atcatttctg cagcagtttt attgatcctg attatggatc cgctcggaaa
    79561 cctacctatt ttcatgtccg tactgaaaca tactgaaccg aaaagacggc gggcaatcat
    79621 ggtgcgagag ttgcttattg ctctcctggt gatgctggtg ttcctgtttg cgggtgagaa
    79681 aattctggca tttctcagcc tgcgagcaga aaccgtctcc atttctggcg gcatcattct
    79741 gtttctaatt gccattaaga tgattttccc cagcgcttca ggaaatagca gcgggcttcc
    79801 ggcaggtgaa gagccattta tcgtgccgtt ggcaattccg ttagtcgccg ggccgactat
    79861 tctcgccacg ctgatgttgt tgtctcatca gtacccgaat cagatggggc atctggtgat
    79921 tgctctgctg ctggcctggg gcggcacctt tgtcatcctg ctacagtctt cgctattttt
    79981 acgtctgctg ggcgagaaag gggtgaacgc acttgaacgc ctgatgggat tgattctggt
    80041 gatgatggca acccagatgt tcctcgacgg cattcgaatg tggatgaagg ggtaacgagg
    80101 agagtttttc gaaaagaacc cggtagtgtc acaactaccg ggcgaacaaa cttaactcaa
    80161 cagctggaac gcaatcatcc caacgatggc accgacagtg ccgaggatgg tttccatcat
    80221 ggtccaggtt ttcagcgttt cggcttcggt cgcgccggta aatttaccga acaaccagaa
    80281 accggcgtcg ttaacgtggc tgacaacaat cgaaccacca gcgatacaaa tcgacagcgc
    80341 cgccatttgc gcaccggagt agttcagttg ttcaataacc ggcatcacca gtcctaccgc
    80401 cgttaaacag gctacggtgg cagaaccctg aatgatgcgc actgcagctg ccagcacgaa
    80461 gcaggtgata gcaatcggca ggcccatgcc ggttaacgct tcgcccagtg ccggacctac
    80521 gccagagtca accagcacct gtttgaacac gccgcctgca ccaatcacca gcagaatgat
    80581 ccccgccggt tgcagcgcgt gaccgcaaat ctccatcact ttgtcttttg gcatgccctg
    80641 acgcattgcc aggccataaa tcgctaccag acaagcaacc agaatcgcgg taaacggatg
    80701 accaataaac tcgaaccatt cgtaagcggt agagccttct ggcacaaaac gcgcggcaat
    80761 ggttttcagc cccaccagca ccagcggcaa caggatcagc gacaggctga atccgaaaga
    80821 tggcattttg ccttcgccga gatgcggttc gctgatgtcg tcaggaatat gcaactccac
    80881 gtagcggctg atgaaattac cccacagcgg cccggcaata atcattcccg gaattgccgc
    80941 acacaggcca atcaggatca tccagccaaa atcggcgttc atctgcgatg cgaggagcat
    81001 tggcgctggc ccaggcacca ggaacgcagc cgcggccgcc acgcctgcga ataatgggat
    81061 taccagcttc accaggttcg taccggtgtg gcgcgccatt gagaaagcaa cgctaatcag
    81121 cagaacaatc gccacttcaa agaacagcgg tagcgcacag accagccccg caaggccgat
    81181 ggcataatgc gcgcggctgt gaccgaagga tttgagcatt ttgacggcaa tctgatcgac
    81241 tgcgccggtt tcatgtaaga tcttgccaaa catagctccc agggcgacaa ccaccgccag
    81301 gaagccgagg gtgcctccca tccctttttc catcgtcgct gcgattttat cgagcggcat
    81361 accggaaaaa aggccagccc ccatggacac caccatcaaa gccaggaaag cgtgcatacg
    81421 cgccttcatg actaaaaaca gcagcagtaa aacagaccct actgctgtta aaacaagcgt
    81481 taatgtagtc actacttatt tgcctttttt aataacctca atggtgcttg ccacaacacc
    81541 ttccagcggt tgatcgatat ccaccaccag tacatcagtt tcgtccgcac ccggctcctg
    81601 cagcgtttca aactgcgtca ccaacatttg ggttttaaag aaatggcctt tgcgcgcttt
    81661 caggcggctt tcaatcacgt caaaatcgcc tttcaggtag atgaaagaga gattcggatt
    81721 accttcacgc agcaagtcgc gatagtgttt tttcaatgca gaacagacga tcagtgacac
    81781 tttattagtg cgctgcatag caaacgcggc gtcgttcagc gcctgcaacc acggtttgcg
    81841 atcgtcgtca ttcagcggtt cgccagacgc cattttttcg atattgcgcc gtggatggag
    81901 gaaatcgcca tcaagaaacg cggcatgaag ttgatgcgcc acttcactgg cgaccgcaga
    81961 tttgccgctg cctgagacgc ccatcaagac gtaaatgtgg tgatcatggt tagtcgtgct
    82021 caaagtggtg cccccacaat acaagaatta aaaatgttac gggcaactgt tatcggtaac
    82081 attgtccggc cggacaatat cagaagcaat atccatccgt gccttaagtg tataagtgtg
    82141 agctacttca aatttgtggg cttaaataga tccgcccggt gacaaggtga aacctaaatc
    82201 taacattttc ggtgtcacag attcgccacg aatacgcgcc agcaggcgtt cagcgccaat
    82261 actgcccatc cgctcacgcg gcgtcagcac gctcgccagt cgtggctcca tcacctgacc
    82321 aatgtcatga ccgtggaaac cggcaatcgc catatcgtca ggaactttta accccagacg
    82381 ctgacattca aacgccgcgc cgaccgccag atcatcatta gtacagaaca cgccatccag
    82441 ctgcggatat tcccgccgcg cctggcgaat cagttcaata ccggaagagt aagaagaaga
    82501 ttgctcaacc atcacgctat acggcaccag gcctgcatcc agcatcgcct gttcgtatcc
    82561 cttctgtttg atgatagtac gttcgtcgag acgtgcgccg agataggcaa tgtggcgatg
    82621 cccgcgcgca ataatggcgg tagtcatctg gcgtgccgct tcaaagttat caaaaccgac
    82681 ggcgatatcg aggcacggcg actggctgtc catcaactcc accaccggga tccccgccac
    82741 ttcaatcatc tttaaggtgc gcggcgtgtg ggtacgttcg gtgaggatca ggccgtcgat
    82801 attccaggac agcatggatt cgagacgttc ttgctccatt tccggtttat aaccgtagtg
    82861 cgccagcatc gtctgataac cgtgcgcgtc ggtgacgctt tcgattccgc gtaatacttc
    82921 cgcgaaaacc tggttggtga gagaaggtaa caggacgcca atcgcccggc tggtagcgtt
    82981 agagaggata tcgggcgcac gattgggaat atagcccagt tcatcaagag cggcggcaat
    83041 cttgccgcgt agagcgacgg aaacctgctc cgggttacgc aaaaagcggc tgaccgtcat
    83101 tttggtcacg cctacacggt cagccacatc ctgaagtacg ggtcttttct ttttcatcgt
    83161 cctgaaggta caaaagagat agattctctt agtttaacac ggacgcatca gaaccttccc
    83221 ggggaaaaca gtgcttgttt acaattatta gatatacact aaatcaattg catcgcattg
    83281 tgctaacgac gcggcaaaac cccggaagcg tgcatcagca cgcgaccgga gcgagcgagg
    83341 aagcctgcaa aaaggcaggc ttcaaagatg ccgttgagtt ttaaaccggc ggcagatcga
    83401 acagtaacac ttcgctgtcg ctatccgcat ggatggagat tgcctgctca tcccagattg
    83461 ccagaccatc gctggtcgag gctttcacgc cgttaatggt gacattgcct ttcaccacct
    83521 ggatccagac gcggcgttca gcggcaatct gatgcaccga ctgctcatct ttcagcaacg
    83581 cccaacgata cagttccata tcctgatgca ctttcagcga accatctcgc gcatccggcg
    83641 agagcaccag ctgtttgccc tgcacggcat cgaagcgacg ctgttcataa cgcggcgtaa
    83701 tgccattttc ttcaggcatg atccagatct gatacagatg cagacgctcg gtgctgcttg
    83761 ggttgtactc tgagtgacga atacccgtac ccgcactcat aatctggaac tcacccgccg
    83821 gaacctgctc tttattgccc atgctgtcct gatgctcaac agtaccttcc agcacgtagg
    83881 tcaaaatttc catatcttta tgcgggtgag tgccgaagcc ctgccctgct tcaatcacgt
    83941 cgtcgttaat cacgcgcagc gcggaaaagc ccataaagtt cggatcgtaa tagttggcaa
    84001 aagagaaagt atgccaggag tccagccagc catgatttgc atgaccacgt tcatttgctt
    84061 tgcgtaagta gatcatttgt attcgcccca tgaatgattt cgatgggctt agtgtggacc
    84121 cgatctgcct gggatgatag agggtgaaaa ttgacccctc tgttcaaaaa aattgaacta
    84181 ttcgaggggc catcaaactt acttagcgag agttactgtg gagggagagg cttgctcaaa
    84241 tccgcgttca aggatttcca gattcgtaag aacttcagat tccttgacgt aatttggcgc
    84301 accgtgggtg atggtttgat acaacgcatc ataaacgcgc ccgtaatcgc ccatctccgg
    84361 cttcatctct tctctgaccg tcacgccctc gtcattgaca tactccagca caccgaccga
    84421 atcatccgct gcgaatcccg gttcgcccgg cataatatta gccttcaggc tggtttcctg
    84481 ctggtcgata ccgtatttaa taaacgaacc tttcttaccg tgaacgataa atttcggata
    84541 atcgattttc accagatggc tggttttgac gatggctttc aggtcgccat aaaacagttg
    84601 cgcttcaaag gtgtcgtcag gattggcttt attacgcagg ctgcggatgt cataagcgac
    84661 gtgatccggg cgaccgaaca gagaaataat ctggtccatc gtatgcacac caaggccata
    84721 aaacgcgcca tcctgcggca gcccaggttt ggtctctgcc accgggcggt aatagtcaaa
    84781 atggctttcc acttcaacaa tctctcccaa cttgccactt tcaatcgctt ttttcgctgt
    84841 caggaagcag gagtcaaagc gacgattctg atacggcgtg acggtcagcc ctttgctttt
    84901 cgccaacgca aacagctcct tcgcctgggc aagcgtcggg gtgaacggtt tttcgaccag
    84961 cacatttttc ccggcttcca gcgcgcgttt cgcgtactcg aaatggctgt ccgcgtgggt
    85021 gcagacaaca accagcttaa catcgggatc gtttagtact tcgtcgagat cgctggtgaa
    85081 atggatatgg gaataaatgg gagcctgttc ttccggcttc gcatggcgac gaaaaatatg
    85141 cgcgacatgc cagctatcct tgcggttaag tacatacggc agatggtaac gggtggtgct
    85201 tttgccgaag ccaataaagg cgcagttgat gaccatgatt tcgtcctttt taaggtggtt
    85261 atttacacct tagcgcaaag cggacgtggt tcctactgga gtgcgcataa cgaacacaag
    85321 cactcccgtg gataaattga gaacgaaaga tcaaaaaaaa agccagcacc cggctggcta
    85381 agtaatactg gaagcaatgt gagcaatgtc gtgctttcag gttctccgcg agggtcttcc
    85441 tgatcgcgag acaataataa tcattctcat tcgcacttgt ccaacacttt ttgcaaaaaa
    85501 atgcatttga ctcgcatttg aaagtcaatg atgttgaaag ggacatttac cccaaagagg
    85561 acaaaggaat gagtgagata gtaatacgcc acgcagaaac acgggattac gaggccatca
    85621 ggcagattca cgcccagccg gaggtgtatt gcaacacact acaggtgcct catccttccg
    85681 atcatatgtg gcaggagcga ctcgccgatc gtcccggcat caagcaactc gtcgcctgta
    85741 ttgatggaga cgtcgtgggc catctcacca ttgacgtgca acagcgccca cgccgcagtc
    85801 atgttgccga ttttggtatc tgtgtcgact ctcgttggaa gaaccgcggc gtcgccagcg
    85861 ccctgatgcg agagatgatt gaaatgtgcg acaactggtt gcgggtagat cgcattgaac
    85921 taaccgtgtt tgtcgataac gccccggcaa ttaaggtcta taaaaaatac ggctttgaaa
    85981 ttgaagggac tggtaagaag tacgcattgc gtaatggtga atatgtcgat gcatattata
    86041 tggcgcgggt gaagtaagat agtgcccttt ttctgagatg gaaaaagggt gtcattcaaa
    86101 atcgacatac cttcctttaa ggtat
//
LOCUS       DAPGUL010000008        83577 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.008, whole genome shotgun sequence.
ACCESSION   DAPGUL010000008 DAPGUL010000000
VERSION     DAPGUL010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 83577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 83577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..83577
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.008"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(208..753)
                     /gene="hemG"
                     /locus_tag="RHX21_000608"
     CDS             complement(208..753)
                     /gene="hemG"
                     /locus_tag="RHX21_000608"
                     /EC_number="1.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="menaquinone-dependent protoporphyrinogen IX
                     dehydrogenase"
                     /protein_id="HDV1985846.1"
                     /translation="MKTLILFSTRDGQTREIASYLASELKELGIQADVANVHRIEEPQ
                     WENYDRVVIGASIRYGHYHSAFQEFVKKHATRLNSMPSAFYSVNLVARKPEKRTPQTN
                     SYARKFLMNSQWRPDRCAVIAGALRYPRYRWYDRFMIKLIMKMSGGETDTRKEVVYTD
                     WEQVANFAREIAHLTDKPTLK"
     gene            complement(765..2216)
                     /gene="trkH"
                     /locus_tag="RHX21_000609"
     CDS             complement(765..2216)
                     /gene="trkH"
                     /locus_tag="RHX21_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkH"
                     /protein_id="HDV1985847.1"
                     /translation="MHFRAITRIVGLLVILFSGTMIIPGLVALIYRDGAGRAFTQTFF
                     VALAIGSMLWWPNRKEKGELKSREGFLIVVLFWTVLGSVGALPFIFSESPNLTITDAF
                     FESFSGLTTTGATTLVGLDSLPHAILFYRQMLQWFGGMGIIVLAVAILPILGVGGMQL
                     YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTVACALALWFAGMDAFDAIGHSFATI
                     AIGGFSTHDASIGYFDSPTINTIIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRM
                     FIGVQFTLVVICTLVLWFHNVYSSALMTINQAFFQVVSMATTAGFTTDSIARWPLFLP
                     VLLLCSAFIGGCAGSTGGGLKVIRILLLFKQGNRELKRLVHPNAVYSIKLGNRALPER
                     ILEAVWGFFSAYALVFIVSMLAIIATGVDDFSAFASVVATLNNLGPGLGVVADNFTSM
                     NPVAKWILIANMLFGRLEVFTLLVLFTPTFWRE"
     gene            complement(2255..2869)
                     /locus_tag="RHX21_000610"
     CDS             complement(2255..2869)
                     /locus_tag="RHX21_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418290.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMPACT family protein"
                     /protein_id="HDV1985848.1"
                     /translation="MESWLIPAAPVTVVEEIKKSRFITMLAHTDGVEAAKAFVESVRA
                     EHPDARHHCVAWVAGAPDDSQQLGFSDDGEPAGTAGKPMLAQLMGSGVGEITAVVVRY
                     YGGILLGTGGLVKAYGGGVNQALRQLTTQRKTPLTEYTLQCEYHQLTGIEALLGQCDG
                     KIINSDYQAFVLLRVALPAAKVAEFSAKLADFSRGSLQLLAIEE"
     gene            complement(2869..4200)
                     /gene="pepQ"
                     /locus_tag="RHX21_000611"
     CDS             complement(2869..4200)
                     /gene="pepQ"
                     /locus_tag="RHX21_000611"
                     /EC_number="3.4.13.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidase"
                     /protein_id="HDV1985849.1"
                     /translation="MESLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLD
                     DHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPTSFWTE
                     DVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRS
                     FKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIV
                     ALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKD
                     VNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMP
                     HGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIES
                     LLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA"
     gene            4390..6579
                     /gene="fadB"
                     /locus_tag="RHX21_000612"
     CDS             4390..6579
                     /gene="fadB"
                     /locus_tag="RHX21_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid oxidation complex subunit alpha FadB"
                     /protein_id="HDV1985850.1"
                     /translation="MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGEAIG
                     VLEQQSDLKGLLLRSNKAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLP
                     VPTIAAVNGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRMPRMLGA
                     DSALEIIAAGKDVGADQALKIGLVDGVVKAEKLVEGAKAVLRQAINGDLDWKAKRQPK
                     LEPLKLSKIEATMSFTIAKGMVAQTAGKHYPAPITAVKTIEAAARFGREEALNLENKS
                     FVPLAHTNEARALVGIFLNDQYVKGKAKKLTKDVETPKQAAVLGAGIMGGGIAYQSAW
                     KGVPVVMKDINDKSLTLGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFDR
                     VDIVVEAVVENPKVKKAVLAETEQKVRQDTVLASNTSTIPISELANALERPENFCGMH
                     FFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPIVVNDCPGFFVNRVLFPYFA
                     GFSQLLRDGADFRKIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPQRMQK
                     DYRDAIDALFDANRFGQKNGLGFWRYKEDSKGKPKKEEDAAVEDLLAEVSQPKRDFSE
                     EEIIARMMIPMVNEVVRCLEEGIIATPAEADMALVYGLGFPPFHGGAFRWLDTLGSAK
                     YLDMAQQYQHLGPLYEVPEGLRNKARHNEPYYPPVEPARPVGDLKTA"
     gene            6589..7752
                     /gene="fadA"
                     /locus_tag="RHX21_000613"
     CDS             6589..7752
                     /gene="fadA"
                     /locus_tag="RHX21_000613"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase FadA"
                     /protein_id="HDV1985851.1"
                     /translation="MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPA
                     LEAAALDDIYWGCVQQTLEQGFNIARNAALLAEVPHSVPAVTVNRLCGSSMQALHDAA
                     RMIMTGDAQACLVGGVEHMGHVPMSHGVDFHPGLSRNVAKAAGMMGLTAEMLARMHGI
                     SREMQDAFAARSHARAWAATQSAAFKNEIIPTGGHDADGVLKQFNYDEVIRPETTVEA
                     LATLRPAFDPVNGMVTAGTSSALSDGAAAMLVMSESRAHELGLKPRARVRSMAVVGCD
                     PSIMGYGPVPASKLALKKAGLSASDIGVFEMNEAFAAQILPCIKDLGLIEQIDEKINL
                     NGGAIALGHPLGCSGARISTTLLNLMERKDVQFGLATMCIGLGQGIATVFERV"
     gene            complement(8035..8736)
                     /gene="fre"
                     /locus_tag="RHX21_000614"
     CDS             complement(8035..8736)
                     /gene="fre"
                     /locus_tag="RHX21_000614"
                     /EC_number="1.5.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-flavin reductase"
                     /protein_id="HDV1985852.1"
                     /translation="MTTLSCKVTSVEAITDTVYRVRIVPDAAFSFRAGQYLMVVMDER
                     DKRPFSMASTPDEKGFIELHIGASEINLYAKAVMDRILKDHQIVVDIPHGEAWLRDDE
                     ERPMILIAGGTGFSYARSILLTALARNPNRDITIYWGGREEQHLYDLCELEALSLKHP
                     GLQVVPVVEQPEAGWRGRTGTVLTAVLQDHGTLAEHDIYIAGRFEMAKIARDLFCSER
                     NAREDRLFGDAFAFI"
     gene            complement(8782..10275)
                     /gene="ubiD"
                     /locus_tag="RHX21_000615"
     CDS             complement(8782..10275)
                     /gene="ubiD"
                     /locus_tag="RHX21_000615"
                     /EC_number="4.1.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-polyprenylbenzoate decarboxylase"
                     /protein_id="HDV1985853.1"
                     /translation="MDAMKYNDLRDFLTLLEQQGELKRITLPVDPHLEITEIADRTLR
                     AGGPALLFENPKGYSMPVLCNLFGTPKRVAMGMGQEDVSALREVGKLLAFLKEPEPPK
                     GFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKIVSGDDVDLNRIPIMTCWPEDAAPLIT
                     WGLTVTRGPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGALDYQEWCAAHPGERFPVS
                     VALGADPATILGAVTPVPDTLSEYAFAGLLRGTKTEVVKCISNDLEVPASAEIVLEGY
                     IEQGETAPEGPYGDHTGYYNEVDSFPVFTVTHITQREDAIYHSTYTGRPPDEPAVLGV
                     ALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQF
                     MYTKFVIVCDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPVSGLGSK
                     MGLDATNKWPGETQREWGRPIKKDPDVVAHIDAIWDELAIFNNGKSA"
     gene            10442..10930
                     /gene="rfaH"
                     /locus_tag="RHX21_000616"
     CDS             10442..10930
                     /gene="rfaH"
                     /locus_tag="RHX21_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription/translation regulatory transformer
                     protein RfaH"
                     /protein_id="HDV1985854.1"
                     /translation="MQSWYLLYCKRGQLQRAQEHLERQAVNCLAPMITLEKIVRGKRT
                     AVSEPLFPNYLFVEFDPEVIHTTTINATRGVSHFVRFGASPAIVPSAVIHQLSVYKPK
                     DIVDPATPYPGDKVIITEGAFEGFQAIFTEPDGEARSMLLLNLINKEIKHSVKNTEFR
                     KL"
     gene            complement(10927..11709)
                     /gene="tatD"
                     /locus_tag="RHX21_000617"
     CDS             complement(10927..11709)
                     /gene="tatD"
                     /locus_tag="RHX21_000617"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' ssDNA/RNA exonuclease TatD"
                     /protein_id="HDV1985855.1"
                     /translation="MFDIGVNLTSSQFAKDRDDVVARAFDAGVNGLLITGTNLRESQQ
                     AQKLARQYSSCWSTAGVHPHDSSQWQAATEEAIIELAAQPEVVAIGECGLDFNRNFST
                     PEEQERAFVAQLRIAADLNMPVFMHCRDAHERFMTLLEPWLDKLPGAVLHCFTGTREE
                     MQACVAHGIYIGITGWVCDERRGLELRELLPLIPAEKLLIETDAPYLLPRDLTPKPSS
                     RRNEPAHLPHILQRIAHWRGEDAAWLAATTDANVKTLFGIAF"
     gene            complement(11751..12527)
                     /gene="tatC"
                     /locus_tag="RHX21_000618"
     CDS             complement(11751..12527)
                     /gene="tatC"
                     /locus_tag="RHX21_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatC"
                     /protein_id="HDV1985856.1"
                     /translation="MSVEDTQPLITHLIELRKRLLNCIIAVIVIFLCLVYFANDIYHL
                     VSAPLIKQLPQGSTMIATDVASPFFTPIKLTFMVSLILSAPVILYQVWAFIAPALYKH
                     ERRLVVPLLVSSSLLFYIGMAFAYFVVFPLAFGFLANTAPEGVQVSTDIASYLSFVMA
                     LFMAFGVSFEVPVAIVLLCWMGITSPEDLRKKRPYVLVGAFVVGMLLTPPDVFSQTLL
                     AIPMYCLFEIGVFFSRFYVGKGRNREEENDAEAESEKTEE"
     gene            complement(12530..13045)
                     /gene="tatB"
                     /locus_tag="RHX21_000619"
     CDS             complement(12530..13045)
                     /gene="tatB"
                     /locus_tag="RHX21_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatB"
                     /protein_id="HDV1985857.1"
                     /translation="MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRSLRSLAT
                     TVQNELTQELKLQEFQDSLKKVEKASLTNLTPELKASMDELRQAAESMKRSYVANDPE
                     KASDEAHTIHNPVVKDNEAAHEGVTPAAAQTQASSPEQKPETTPEPVVKPAADAEPKT
                     AAPSPSSSDKP"
     gene            complement(13049..13318)
                     /gene="tatA"
                     /locus_tag="RHX21_000620"
     CDS             complement(13049..13318)
                     /gene="tatA"
                     /locus_tag="RHX21_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatA"
                     /protein_id="HDV1985858.1"
                     /translation="MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMS
                     DDEPKQDKTSQDADFTAKTIADKQADTNQEQAKTEDAKRHDKEQV"
     gene            complement(13397..15037)
                     /gene="ubiB"
                     /locus_tag="RHX21_000621"
     CDS             complement(13397..15037)
                     /gene="ubiB"
                     /locus_tag="RHX21_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis regulatory protein
                     kinase UbiB"
                     /protein_id="HDV1985859.1"
                     /translation="MTPGEVRRLYFIIRTFLSYGLDELIPKMRITLPLRLWRYSLFWM
                     PNRHKDKLLGERLRLALQELGPVWIKFGQMLSTRRDLFPPHIADQLALLQDKVAPFDG
                     KLAKQQIEAAMGGLPVEAWFDDFEIKPLASASIAQVHTARLKSNGKEVVIKVIRPDIL
                     PVIKADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLLRESANAIQLRR
                     NFEDSPMLYIPEVYPDYCSEGMMVMERIYGIPVSDVAALEKNGTNMKLLAERGVQVFF
                     TQVFRDSFFHADMHPGNIFVSYEHPENPKYIGIDCGIVGSLNKEDKRYLAENFIAFFN
                     RDYRKVAELHVDSGWVPPDTNVEEFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTAR
                     RFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGIPALVRAF
                     KEKAPFWVEKMPELPELVYDSLRQGKYLQHSVDKIARELQSNHVRQGQSRYFLGIGAT
                     LVLSGTFLLVSRPEWGLMPGWLMAGGLIAWFVGWRKTR"
     gene            complement(15034..15639)
                     /gene="ubiJ"
                     /locus_tag="RHX21_000622"
     CDS             complement(15034..15639)
                     /gene="ubiJ"
                     /locus_tag="RHX21_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis protein UbiJ"
                     /protein_id="HDV1985860.1"
                     /translation="MPFKPLVTAGIESLLNTFLYRSPALKTARSRLLGKVLRVEVKGF
                     STSLILVFSERQVDVLGEWAGDADCTVIAYASVLPKLRDRQQLTALIRSGELEVQGDI
                     QVVQNFVALADLAEFDPAELLAPYTGDIAAEGISKAMRGGAKFLHHGIKRQQRYVAEA
                     ITEEWRMAPGPLEVAWFAEETAAVERAVDALTKRLEKLEAK"
     gene            complement(15653..16408)
                     /gene="ubiE"
                     /locus_tag="RHX21_000623"
     CDS             complement(15653..16408)
                     /gene="ubiE"
                     /locus_tag="RHX21_000623"
                     /EC_number="2.1.1.163"
                     /EC_number="2.1.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional demethylmenaquinone
                     methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol
                     methylase UbiE"
                     /protein_id="HDV1985861.1"
                     /translation="MVDKSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMS
                     FGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRLVGETGKVVLADINESMLK
                     MGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTDKDKALRSMYRVL
                     KPGGRLLVLEFSKPIIEPLSKAYDAYSFHVLPRIGSLVANDADSYRYLAESIRMHPDQ
                     DTLKAMMQDAGFESVDYYNLTAGVVALHRGYKF"
     gene            complement(16503..17930)
                     /gene="rmuC"
                     /locus_tag="RHX21_000624"
     CDS             complement(16503..17930)
                     /gene="rmuC"
                     /locus_tag="RHX21_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HDV1985862.1"
                     /translation="MDFSIMVYAVIALVGVAIGWLFASYQHAQQKAEQLAEREEMVAE
                     LSAAKQQITQSEHWRAECELLNNEVRSLQSINTSLEADLREVTTRMEAAQQHADDKIR
                     QMINSEQRLSEQFENLANRIFEHSNRRVDEQNRQSLNSLLSPLREQLDGFRRQVQDSF
                     GKEAQERHTLTHEIRNLQQLNAQMAQEAINLTRALKGDNKTQGNWGEVVLTRVLEASG
                     LREGYEYETQVSIENDARSRMQPDVIVRLPQGKDVVIDAKMTLVAYERYFNAEDDYTR
                     ESALQEHIASVRNHIRLLGRKDYQQLPGLRTLDYVLMFIPVEPAFLLALDRQPELITE
                     ALKNNIMLVSPTTLLVALRTIANLWRYEHQSRNAQQIADRASKLYDKMRLFVDDMSAI
                     GQSLDKAQDNYRQAMKKLSSGRGNVLAQAEAFRGLGVEIKREINPDLAEQAVSQDEEY
                     RLRSVPEQPNDEAYQRDDEYNQQSR"
     gene            complement(18071..18832)
                     /gene="udp"
                     /locus_tag="RHX21_000625"
     CDS             complement(18071..18832)
                     /gene="udp"
                     /locus_tag="RHX21_000625"
                     /EC_number="2.4.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine phosphorylase"
                     /protein_id="HDV1985863.1"
                     /translation="MSKSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKL
                     ASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHI
                     NVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSD
                     TFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAG
                     VIVNRTQQEIPNAETMKQTESQAVKIVVEAARRLL"
     gene            19094..19909
                     /locus_tag="RHX21_000626"
     CDS             19094..19909
                     /locus_tag="RHX21_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312787.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HDV1985864.1"
                     /translation="MATTQQSGFAPAASPLASTIVQTPDDAIVAGFTSIPSQGDNMPA
                     YHARPKQSDGPLPVVIVVQEIFGVHEHIRDICRRLALEGYLAIAPELYFREGDPNDFA
                     DIPTLLSGLVAKVPDSQVLADLDHVASWASRNGGDVHRLMITGFCWGGRITWLYAAHN
                     PQLKAAVAWYGKLTGDKSLNSPKQPVDIATDLNAPVLGLYGGLDNSIPQESVETMRQA
                     LRAANAKAEIIVYPDAGHAFNADYRPSYHAASAKDGWQRMLEWFKQYGGKKSL"
     gene            complement(19949..22210)
                     /gene="metE"
                     /locus_tag="RHX21_000627"
     CDS             complement(19949..22210)
                     /gene="metE"
                     /locus_tag="RHX21_000627"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HDV1985865.1"
                     /translation="MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELR
                     ARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPARHQNKDGSVDIDTLFRIGRG
                     RAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLDEVDEALALGHKVKPV
                     LLGPVTWLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELP
                     QAWLDAYKPAYDALQGQVKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVAEL
                     HKRLPSDWLLSAGLINGRNVWRADLTEKYAQIKDIVGKRDLWVASSCSLLHSPIDLSV
                     ETRLDAEVKSWFAFALQKCHELALLRDALNSGDTAALAEWSVPIQARRHSTRVHNPAV
                     EKRLATITAQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKG
                     NLDANNYRTGIAEHIRQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGW
                     VQSYGSRCVKPPIVIGDVSRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPRE
                     DVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDAYLQWGVEA
                     FRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDY
                     PNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAAL
                     ANMVQAAQNLRRG"
     gene            22447..23400
                     /gene="metR"
                     /locus_tag="RHX21_000628"
     CDS             22447..23400
                     /gene="metR"
                     /locus_tag="RHX21_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MetR"
                     /protein_id="HDV1985866.1"
                     /translation="MIEVKHLKTLQALRNCGSLAAAAATLHQTQSALSHQFSDLEQRL
                     GFRLFVRKSQPLRFTPQGEILLQLANQVLPQISQALQACNEPQQTRLRIAIECHSCIQ
                     WLTPALENFHKNWPQVEMDFKSGVTFDPQPALQQGELDLVMTSDILPRSGLHYSPMFD
                     YEVRLVLAPDHPLAAKTRITPEDLASETLLIYPVQRSRLDVWRHFLQPAGVSPSLKSV
                     DNTLLLIQMVAARMGIAALPHWVVESFERQGLVVTKTLGEGLWSRLYAAVRDGEQRQP
                     VTEAFIRSARNHACDHLPFVKSAERPTYDAPTVRPGSPARL"
     gene            complement(23288..24187)
                     /gene="bioP"
                     /locus_tag="RHX21_000629"
     CDS             complement(23288..24187)
                     /gene="bioP"
                     /locus_tag="RHX21_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter"
                     /protein_id="HDV1985867.1"
                     /translation="MALLIITTILWAFSFSFYGEYLAGHVDSYFAVLVRVGLAALVFL
                     PFLRTRGNSLKTVGLYMLVGAMQLGVMYMLSFRAYLYLTVSELLLFTVLTPLYITLIY
                     DIMSKRRLRWGYAFSALLAVIGAGIIRYDQVTDHFWTGLLLVQLSNITFAIGMVGYKR
                     LMETRPMPQHNAFAWFYLGAFLVAVIAWFLLGNAQKMPQTTLQWGILVFLGVVASGIG
                     YFMWNYGATQVDAGTLGIMNNMHVPAGLLVNLAIWHQQPHWPTFITGALVILASLWVH
                     RKWVAPRSSQTADDRRRDCALSE"
     gene            complement(24263..25063)
                     /gene="yigL"
                     /locus_tag="RHX21_000630"
     CDS             complement(24263..25063)
                     /gene="yigL"
                     /locus_tag="RHX21_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar/pyridoxal phosphate phosphatase YigL"
                     /protein_id="HDV1985868.1"
                     /translation="MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGR
                     HHVDVGQIRDNLEIKSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDII
                     TNVYRDDEWFMNRHRPEEMRFFKEAVFKYALYEPGLLEPEGVSKVFFTCDSHEQLLPL
                     EQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMND
                     AEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNAEDAVPHYLRKLYLS"
     gene            complement(25071..26093)
                     /gene="pldB"
                     /locus_tag="RHX21_000631"
     CDS             complement(25071..26093)
                     /gene="pldB"
                     /locus_tag="RHX21_000631"
                     /EC_number="3.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipase L2"
                     /protein_id="HDV1985869.1"
                     /translation="MFQQQKDWETRENAFAAFTMGPLTDFWRQRDEAEFTGVDDIPVR
                     FVRFRAQHHDRVVVICPGRIESYVKYAELAYDLFHLGFDVLIIDHRGQGRSGRLLADP
                     HLGHVNRFNDYVDDLAAFWQQEVQPGPWRKRYILAHSMGGAISTLFLQRHPGVCDAIA
                     LTAPMFGIVIRMPSFMARQILNWAEAHPRFRDGYAIGTGRWRALPFAINVLTHSRQRY
                     RRNLRFYADDPTIRVGGPTYHWVRESILAGEQVLAGAGDDATPTLLLQAEEERVVDNR
                     MHDRFCELRTAAGHPVEGGRPLVIKGAYHEILFEKDAMRSVALHAIVDFFNRHNSPSG
                     NRSTEV"
     gene            26204..26824
                     /gene="rhtB"
                     /locus_tag="RHX21_000632"
     CDS             26204..26824
                     /gene="rhtB"
                     /locus_tag="RHX21_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine/homoserine lactone efflux protein"
                     /protein_id="HDV1985870.1"
                     /translation="MTLEWWFAYLLTSIILSLSPGSGAINTMTTSLNHGYRGAVASIA
                     GLQTGLAVHIVLVGVGLGTLFSRSVIAFEVLKWAGAAYLIWLGIQQWRAAGAIDLKSL
                     ASTQSRRHLFQRAVFVNLTNPKSIVFLAALFPQFIMPQQPQLMQYIVLGVTTIVVDII
                     VMIGYATLAQRIALWIKGPKQMKALNKIFGSLFMLVGALLASARHA"
     gene            complement(26886..27506)
                     /gene="rhtC"
                     /locus_tag="RHX21_000633"
     CDS             complement(26886..27506)
                     /gene="rhtC"
                     /locus_tag="RHX21_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709629.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine export protein RhtC"
                     /protein_id="HDV1985871.1"
                     /translation="MLMLFLTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLG
                     ITCGVMVWAGIALLGLHLIIEKMAWLHTLIMVGGGLYLCWMGYQMLRGALKKEAVSAP
                     APQVELAKSGRSFLKGLLTNLANPKAIIYFGSVFSLFVGDNVGTTERWGIFALIIVET
                     LAWFTVVASLFALPQMRRGYQRLAKWIDGFAGALFAGFGIHLIISR"
     gene            complement(27570..29399)
                     /gene="recQ"
                     /locus_tag="RHX21_000634"
     CDS             complement(27570..29399)
                     /gene="recQ"
                     /locus_tag="RHX21_000634"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026263.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HDV1985872.1"
                     /translation="MAQAEVLNLESGAKQVLQETFGYQQFRPGQEEIIDTVLSGRDCL
                     VVMPTGGGKSLCYQIPALLLNGLTVVVSPLISLMKDQVDQLQANGVAAACLNSTQTRE
                     QQLEVMTGCRTGQIRLLYIAPERLMLDNFLEHLAHWNPVLLAVDEAHCISQWGHDFRP
                     EYAALGQLRQRFPTLPFMALTATADDTTRQDIVRLLGLNDPLIQISSFDRPNIRYMLM
                     EKFKPLDQLMRYVQEQRGKSGIIYCNSRAKVEDTAARLQSKGISAAAYHAGLENNVRA
                     DVQEKFQRDDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPA
                     EAMLFYDPADMAWLRRCLEEKPQGQLQDIERHKLNAMGAFAEAQTCRRLVLLNYFGEG
                     RQEPCGNCDICLDPPKQYDGSTDAQIALSTIGRVNQRFGMGYVVEVIRGANNQRIRDY
                     GHDKLKVYGMGRDKSHEHWVSVIRQLIHLGLVTQNIAQHSALQLTEAARPVLRGESSL
                     QLAVPRIVALKPKAMQKSFGGNYDRKLFAKLRKLRKSIADESNVPPYVVFNDATLIEM
                     AEQMPITASEMLSVNGVGMRKLERFGKPFMALIRAHVDGDDEE"
     gene            complement(29532..30401)
                     /gene="pldA"
                     /locus_tag="RHX21_000635"
     CDS             complement(29532..30401)
                     /gene="pldA"
                     /locus_tag="RHX21_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase A"
                     /protein_id="HDV1985873.1"
                     /translation="MRTLQGWLLPVFMLPMAVYAQEATVKEVHDAPAVRGSIIANMLQ
                     EHDNPFTLYPYDTNYLIYTQTSDLNKEAIASYDWAENARKDEVKFQLSLAFPLWRGIL
                     GPNSVLGASYTQKSWWQLSNSEESSPFRETNYEPQLFLGFATDYRFAGWTLRDVEMGY
                     NHDSNGRSDPTSRSWNRLYTRLMAENGNWLVEVKPWYVVGNTDDNPDITKYMGYYQLK
                     IGYHLGDAVLSAKGQYNWNTGYGGAELGLSYPITKHVRLYTQVYSGYGESLIDYNFNQ
                     TRVGVGVMLNDLF"
     gene            30566..31033
                     /locus_tag="RHX21_000636"
     CDS             30566..31033
                     /locus_tag="RHX21_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312777.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HDV1985874.1"
                     /translation="MSAVLTAEQALKLVGEMFVYHMPFNRALGMELERYEKEFAQLAF
                     KNQPMMVGNWAQSILHGGVIASALDVAAGLVCVGSTLTRHETISEDELRQRLSRMGTI
                     DLRVDYLRPGRGERFTATSSLLRAGNKVAVARVELHNEEQLYIASATATYMVG"
     gene            31085..31975
                     /gene="rarD"
                     /locus_tag="RHX21_000637"
     CDS             31085..31975
                     /gene="rarD"
                     /locus_tag="RHX21_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter RarD"
                     /protein_id="HDV1985875.1"
                     /translation="MDAKQTRQGVLLALAAYFIWGIAPAYFKLIYYVPADEILTHRVI
                     WSFFFMVVLMSICRQWSYLKTLIQTPQKIFMLAVSAVLIGGNWLLFIWAVNNHHMLEA
                     SLGYFINPLVNIVLGMIFLGERFRRMQWLAVILAICGVLVQLWTFGSLPIIALGLAFS
                     FAFYGLVRKKIAVEAQTGMLIETMWLLPVAAIYLFAIADSSTSHMGQNPMSLNLLLIA
                     AGIVTTVPLLCFTAAATRLRLSTLGFFQYIGPTLMFLLAVTFYGEKPGADKMVTFAFI
                     WVALAIFVMDAIYTQRRTSK"
     gene            32034..32450
                     /locus_tag="RHX21_000638"
     CDS             32034..32450
                     /locus_tag="RHX21_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709624.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1985876.1"
                     /translation="MLTGDSYKDVKFMLRIFIPTSNGKISRRRYIFSFILINFIFAFL
                     IIFFNDGEAGFLVIVSTIVLHYLVINMNCQRLRDSGFIYIKTYVFGTLAVYIISIITM
                     IAEDFACSGNGSMIFLICYFSTFSMLMLAPTDSSKQ"
     gene            32464..32844
                     /locus_tag="RHX21_000639"
     CDS             32464..32844
                     /locus_tag="RHX21_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2628 domain-containing protein"
                     /protein_id="HDV1985877.1"
                     /translation="MSKEYMNDGSLSEKWKYRFNFYDQHGFPGFWGATPEYKAAFKAL
                     KVRQRLTIQMNFIAFFCSWIYLFVLGLWKKAIIVLLLGILSLFVGALIGVNILGIAVA
                     AYVAVNTNKWFYEKEVKGLNTWSL"
     gene            complement(32887..33837)
                     /gene="corA"
                     /locus_tag="RHX21_000640"
     CDS             complement(32887..33837)
                     /gene="corA"
                     /locus_tag="RHX21_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="HDV1985878.1"
                     /translation="MLSAFQLENNRLTRLEVEESQPLVNAVWIDLVEPDDDERLRVQS
                     ELGQSLATRPELEDIEASARFFEDDDGLHIHSFFFFEDAEDHAGNSTVAFTIRDGRLF
                     TLRERELPAFRLYRMRARSQSMVDGNAYELLLDLFETKIEQLADEIENIYSDLEQLSR
                     VIMEGHQGDEYDEALSTLAELEDIGWKVRLCLMDTQRALNFLVRKARLPGGQLEQARE
                     ILRDIESLLPHNESLFQKVNFLMQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSY
                     GMNFEFMPELKWSFGYPGAIIFMILAGLAPYLYFKRKNWL"
     gene            34207..34971
                     /locus_tag="RHX21_000641"
     CDS             34207..34971
                     /locus_tag="RHX21_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiester glycosidase family protein"
                     /protein_id="HDV1985879.1"
                     /translation="MAHRLLIGKGMITLNLKRIFLALTLLPLFAVAADDCALSDPTLT
                     VQAYTVNPQTERVKMYWQKANGEAWGTLHALLADMNSQGQVQMAMNGGIYDESYAPLG
                     LYIENGQQKVALNLASGEGNFFIRPGGVFYVAGDKVGIVRLDAFKTSKEIQFAVQSGP
                     MLMENGVINPRIHPNVASSKIRNGVGINKHGNAVFLLSQQATNFYDFACYAKAKLNVE
                     QLLYLDGTISHMYMKGGAIPWQRYPFVTMISVERKG"
     gene            complement(35118..37280)
                     /gene="uvrD"
                     /locus_tag="RHX21_000642"
                     /gene_synonym="mutU"
                     /gene_synonym="recL"
     CDS             complement(35118..37280)
                     /gene="uvrD"
                     /locus_tag="RHX21_000642"
                     /gene_synonym="mutU"
                     /gene_synonym="recL"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase II"
                     /protein_id="HDV1985880.1"
                     /translation="MDVSYLLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIA
                     WLMSVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHH
                     MDANLPQDFQILDSEDQLRLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQ
                     SYGNPVEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNIL
                     VDEFQDTNNIQYAWIRLLAGDTGKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAET
                     IRLEQNYRSTSNILSAANALIENNNGRLGKKLWTDGADGEPISLYCAFNELDEARFVV
                     NRIKTWQDNGGALAECAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDAL
                     SYLRLIANRNDDAAFERVVNTPTRGIGDRTLDVVRQTSRDRQLTLWQACRELLQEKAL
                     AGRAASALQRFMELIDALAQETADMPLHVQTDRVIKDSGLRTMYEQEKGEKGQTRIEN
                     LEELVTATRQFSYNEEDEDLMPLQAFLSHAALEAGEGQADTWQDAVQLMTMHSAKGLE
                     FPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAYVGVTRAMQKLTLTYAETRRLYGKE
                     VYHRPSRFIGELPEECVEEVRLRATVSRPVSHQRMGTPMVENDSGYKLGQRVRHAKFG
                     EGTIVNMEGSGEHSRLQVAFQGQGIKWLVAAYARLESV"
     gene            complement(37364..38080)
                     /gene="yigB"
                     /locus_tag="RHX21_000643"
     CDS             complement(37364..38080)
                     /gene="yigB"
                     /locus_tag="RHX21_000643"
                     /EC_number="3.1.3.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-amino-6-(5-phospho-D-ribitylamino)uracil
                     phosphatase YigB"
                     /protein_id="HDV1985881.1"
                     /translation="MRFYRPLGRISALTFDLDDTLYDNRPVILRTEREALTFVQNYHP
                     ALRSFQNEDLQRLRQAVREAEPEIYHDVTRWRFRSIEQAMLDAGLSAEEASAGAHAAM
                     INFAKWRSRIDVPQQTHDTLKQLAKKWPLVAITNGNAQPELFGLGDYFEFVLRAGPHG
                     RSKPFSDMYFLAAEKLNVPIGEILHVGDDLTTDVGGAIRSGMQACWIRPENGDLMQTW
                     DSRLLPHLEISRLASLTSLI"
     gene            complement(38080..38976)
                     /gene="xerC"
                     /locus_tag="RHX21_000644"
     CDS             complement(38080..38976)
                     /gene="xerC"
                     /locus_tag="RHX21_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HDV1985882.1"
                     /translation="MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIINFASENG
                     LQSWQQCDVTMVRNFAVRSRRKGLGAASLALRLSALRSFFDWLVSQNELKANPAKGVS
                     APKAPRHLPKNIDVDDMNRLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHL
                     DLESGEVWVMGKGSKERRLPIGRNAVAWIEHWLDLRDLFGSEDDALFLSKLGKRISAR
                     NVQKRFAEWGIKQGLNNHVHPHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYT
                     HLDFQHLASVYDAAHPRAKRGK"
     gene            complement(38973..39680)
                     /locus_tag="RHX21_000645"
     CDS             complement(38973..39680)
                     /locus_tag="RHX21_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF484 domain-containing protein"
                     /protein_id="HDV1985883.1"
                     /translation="MKQPGEELQETLTELDDRAVVDYLIKNPEFFIRNARAVEAIRVP
                     HPVRGTVSLVEWHMARARNHIHVLEENMALLMEQAIANEGLFYRLLYLQRSLTAASSL
                     DDMLMRFHRWARDLGLAGASLRLFPDRWRLGAPSNHTHLALSRQSFEPLRIQRLGQEQ
                     HYLGPLNGPELLVVLPEAKAVGSVAMSMLGSDADLGVVLFTSRDASHYQQGQGTQLLH
                     EIALMLPELLERWIERV"
     gene            complement(39677..40501)
                     /gene="dapF"
                     /locus_tag="RHX21_000646"
     CDS             complement(39677..40501)
                     /gene="dapF"
                     /locus_tag="RHX21_000646"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HDV1985884.1"
                     /translation="MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLADRHLGVGFDQ
                     LLVVEPPYDPELDFHYRIFNADGSEVAQCGNGARCFARFVRLKGLTNKRDIRVSTANG
                     RMVLTVTDDDLVRVNMGEPNFEPSAVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHC
                     VIQVDDVDTAAVETLGPVLESHERFPERANIGFMQVVKREHIRLRVYERGAGETQACG
                     SGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAVHVYDGFIHL"
     gene            complement(40538..40741)
                     /locus_tag="RHX21_000647"
     CDS             complement(40538..40741)
                     /locus_tag="RHX21_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDV1985885.1"
                     /translation="MKNVFKALTVLLTLFSLTGCGLKGPLYFPPADKNAPPPTKPVET
                     QTQSTVPDKNDRATGDGPSQVNY"
     gene            41204..41524
                     /gene="cyaY"
                     /locus_tag="RHX21_000648"
     CDS             41204..41524
                     /gene="cyaY"
                     /locus_tag="RHX21_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000999950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron donor protein CyaY"
                     /protein_id="HDV1985886.1"
                     /translation="MNDSEFHRLADQLWLTIEERLDDWDGDSDIDCEINGGVLTITFE
                     NGSKIIINRQEPLHQVWLATKQGGYHFDLKGDEWICDRSGETFWDLLEQAATQQAGET
                     VSFR"
     gene            complement(41564..44110)
                     /gene="cyaA"
                     /locus_tag="RHX21_000649"
     CDS             complement(41564..44110)
                     /gene="cyaA"
                     /locus_tag="RHX21_000649"
                     /EC_number="4.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I adenylate cyclase"
                     /protein_id="HDV1985887.1"
                     /translation="MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHY
                     HHPLMPGYLDGNVPKGICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMG
                     STSSVGQSCSSDLDIWVCHQSWLDSEERQLLQRKCSLLENWAASLGVEVSFFLIDENR
                     FRHNESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTL
                     YAQGVLTPNEWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYP
                     NPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVC
                     EKLSRERACVGWRRAVLSQLVSEWGWDEARLAMLDNRANWKIDQVREAHNELLDAMMQ
                     SYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLT
                     FIYVPPGRANRSGWYLYNRAPNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLY
                     IKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAF
                     RNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTIL
                     GKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVS
                     GQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSVQVETNHVKLPAVVDGFASEG
                     IIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGS
                     SFINFNLPQFYQIVKVDGREQVIPFRTKSIGNMPPANQDHDTPLLQQYFS"
     gene            44497..45438
                     /gene="hemC"
                     /locus_tag="RHX21_000650"
     CDS             44497..45438
                     /gene="hemC"
                     /locus_tag="RHX21_000650"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HDV1985888.1"
                     /translation="MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTR
                     GDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICERE
                     DPRDAFVSNNYDSLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLD
                     NGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDSRTRELLAA
                     LNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGER
                     RGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA"
     gene            45435..46175
                     /gene="hemD"
                     /locus_tag="RHX21_000651"
     CDS             45435..46175
                     /gene="hemD"
                     /locus_tag="RHX21_000651"
                     /EC_number="4.2.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="HDV1985889.1"
                     /translation="MSILVTRPSPAGEELVSRLRTLGQVAWHFPLIEFSPGQQLPQLA
                     DQLAALGESDLLFALSQHAVAFAQSQLHQQDRKWPRLPDYFAIGRTTALALHTVSGQK
                     ILYPQDREISEVLLQLPELQNIAGKRALILRGNGGRELIGDTLTARGAEVTFCECYQR
                     CAIHYDGAEEAMRWQSREVTMVVVTSGEMLQQLWSLIPQWYREHWLLHCRLLVVSERL
                     AKLARELGWQDIKVADNADNDALLRALQ"
     gene            46197..47438
                     /gene="hemX"
                     /locus_tag="RHX21_000652"
     CDS             46197..47438
                     /gene="hemX"
                     /locus_tag="RHX21_000652"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HDV1985890.1"
                     /translation="MTEQEKTSAVVEETREAVDTTSQPVATEKKSKNNTALILSAVAI
                     AIALAAGVGLYGWGKQQAVNQTATSDALANQLTALQKAQESQKAELEGIIKQQAAQLK
                     QANRQQETLAKQLDEVQQKVATISGSDAKTWLLAQADFLVKLAGRKLWSDQDVTTAAA
                     LLKSADASLADMNDPSLITVRRAITDDIASLSAVSQVDYDGIILKLNQLSNQVDNLRL
                     ADNDSDGSPMDSDGEELSSSISEWRINLQKSWQNFMDNFITIRRRDDTAVPLLAPNQD
                     IYLRENIRSRLLVAAQAVPRHQEETYRQALENVSTWVRAYYDTDDATTKAFLDEVDQL
                     SQQNISMDLPETLQSQAMLEKLMQTRVRNLLAQPAAGTTEAKPAPAPAPAPAPAPAPA
                     PAPAPAPAPQGDTPAAAPQGE"
     gene            47441..48637
                     /gene="hemY"
                     /locus_tag="RHX21_000653"
     CDS             47441..48637
                     /gene="hemY"
                     /locus_tag="RHX21_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX biogenesis protein HemY"
                     /protein_id="HDV1985891.1"
                     /translation="MLKVLLLFVLLIAGIVVGPMIAGHQGYVLIQTDNYNIETSVTGL
                     AIILILAMVVLFAIEWLLRRIFRTGAHTRGWFVGRKRRRARKQTEQALLKLAEGDYQQ
                     VEKLMAKNADHAEQPVVNYLLAAEAAQQRGDEARANQHLERAAELAGNDTIPVEITRV
                     RLQLARNENHAARHGVDKLLEVTPRHPEVLRLAEQAYIRTGAWSSLLDIIPSMAKAHV
                     GDEEHRAMLEQQAWIGLMDQARADNGSEGLRNWWKNQSRKTRHQVALQVAMAEHLIEC
                     DDHDTAQQIIIDGLKRQYDDRLLLPIPRLKTNNPEQLEKVLRQQIKNVGDRPLLWSTL
                     GQSLMKHGEWQEASLAFRAALKQRPDAYDYAWLADALDRLHKPEEAAAMRHDGLMLTL
                     QNNPPQ"
     gene            49316..49477
                     /locus_tag="RHX21_000654"
     CDS             49316..49477
                     /locus_tag="RHX21_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1985892.1"
                     /translation="MEISFSPKRLVVAVAAALPLMASAADTPSTATARKGFAGYDHPN
                     QYPQNAAIY"
     gene            complement(49561..50796)
                     /locus_tag="RHX21_000655"
     CDS             complement(49561..50796)
                     /locus_tag="RHX21_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase maturase"
                     /protein_id="HDV1985893.1"
                     /translation="MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTH
                     MDDDTLEAYIRHYIAASELQNEVAFTWQGGEPTLLGLEFYRRAVALQAKYGAGRKISN
                     SFQTNGVLLDDEWCAFLAEHHFLVGLSLDGPPEIHNQYRVTKGGRPTHKLVMRALTLL
                     QKHHVDYNVLVCVNRTSAQQPLQVYDFLCDAGVEFIQFIPVVERLADETAAREGLKLH
                     APGDIQGELTEWSVRPEEFGEFLVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVC
                     HHQPTCGRSVIVEHNGDVYACDHYVYPQYRLGNMHQQTIAEMIDSPQQQAFGEDKFKQ
                     LPAQCRSCNVLKACWGGCPKHRFMLDASGKPGLNYLCAGYQRYFRHLPPYLKAMADLL
                     AHGRPASDIMHAHLLVVSK"
     gene            complement(50943..51019)
                     /locus_tag="RHX21_000656"
     tRNA            complement(50943..51019)
                     /locus_tag="RHX21_000656"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(50983..50985),aa:Pro,seq:tgg)
     gene            complement(51062..51148)
                     /locus_tag="RHX21_000657"
     tRNA            complement(51062..51148)
                     /locus_tag="RHX21_000657"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(51112..51114),aa:Leu,seq:cag)
     gene            complement(51169..51244)
                     /locus_tag="RHX21_000658"
     tRNA            complement(51169..51244)
                     /locus_tag="RHX21_000658"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(51209..51211),aa:His,seq:gtg)
     gene            complement(51303..51379)
                     /locus_tag="RHX21_000659"
     tRNA            complement(51303..51379)
                     /locus_tag="RHX21_000659"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(51343..51345),aa:Arg,seq:ccg)
     gene            complement(51482..52867)
                     /locus_tag="RHX21_000660"
     CDS             complement(51482..52867)
                     /locus_tag="RHX21_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDV1985894.1"
                     /translation="MADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPS
                     VLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYAHRYMSPFFGYLTAWSYWFMWMA
                     VGISEITAIGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTT
                     IIVMIVIGLGVIFFGFGNGGQSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVEL
                     IGITAGEAKNPQVTLRSAVGKVLWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFA
                     KIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLPAAMAKVSRHGVPVA
                     GVAVSIAILLIGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKAA
                     IASHPFRSILFPWANYVTMAFLICVLIGMYFNEDTRMSLFVGIIFMLAVTAIYKVFGL
                     NRHGKAHKLEE"
     gene            complement(53058..53798)
                     /gene="rffM"
                     /locus_tag="RHX21_000661"
     CDS             complement(53058..53798)
                     /gene="rffM"
                     /locus_tag="RHX21_000661"
                     /EC_number="2.4.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide
                     N-acetylmannosaminouronosyltransferase"
                     /protein_id="HDV1985895.1"
                     /translation="MNNNTTAPTYTLRGLQLIGWRDMQHALDYLFADGQLKQGTLVAI
                     NAEKMLTIEDNAEVRELINAAEFKYADGISVVRSVRKKYPQAQVSRVAGADLWEELMA
                     RAGKEGTPVFLVGGKPEVLAQTEAKLRNQWNVNIVGSQDGYFKPEQRQALFERIHASG
                     AQIVTVAMGSPKQEIFMRDCRLVHPDALYMGVGGTYDVFTGHVKRAPKIWQTLGLEWL
                     YRLLSQPSRIKRQLRLLRYLRWHYTGNL"
     gene            complement(53801..55153)
                     /gene="wzyE"
                     /locus_tag="RHX21_000662"
     CDS             complement(53801..55153)
                     /gene="wzyE"
                     /locus_tag="RHX21_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECA oligosaccharide polymerase"
                     /protein_id="HDV1985896.1"
                     /translation="MSLLQFSGLFVVWLLCTLFIATLTWFEFRRVRFNFNVFFSLLFL
                     LTFFFGFPLTSVLVFRFDVGVAPPEILLQALLSAGCFYAVYYVTYKTRLRKRVADVPR
                     RPLFTMNRVETNLTWVILMGIALVSVGIFFMHNGFLLFRLNSYSQIFSSEVSGVALKR
                     FFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIG
                     IIRGWISLWMLAAAGVLGIVGMFWLALKRYGMNVSGDEAFYTFLYLTRDTFSPWENLA
                     LLLQNYDNIDFQGLAPIVRDFYVFIPSWLWPGRPSMVLNSANYFTWEVLNNHSGLAIS
                     PTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNRETNRYKAAILHSFCFGAIF
                     NMIVLAREGLDSFVSRVVFFIVVFGACLMIAKLLYWLFESAGFIHKRTKSSLRTQVEG
                     "
     gene            complement(55150..56229)
                     /gene="rffT"
                     /locus_tag="RHX21_000663"
                     /gene_synonym="wecF"
     CDS             complement(55150..56229)
                     /gene="rffT"
                     /locus_tag="RHX21_000663"
                     /gene_synonym="wecF"
                     /EC_number="2.4.1.325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDP-N-acetylfucosamine:lipid II
                     N-acetylfucosaminyltransferase"
                     /protein_id="HDV1985897.1"
                     /translation="MTVLIHVLGSDIPHHNRTVLRFFNDALAATSEHAREFMVVGKDD
                     GLSDSCPALSVQFFPGKKSLAEAVIAKAKANRQQRFFFHGQFNPTLWLALLSGGIKPS
                     QFFWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGEL
                     LYFPTRMDPSLNTMANDRQREGKMTILVGNSGDRSNEHIAALRAVHQQFGDTVKVVVP
                     MGYPPNNEAYIEEVRQAGLELFSEENLQILSEKLEFDAYLALLRQCDLGYFIFARQQG
                     IGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDIVREAQRQLASVDKN
                     TIAFFSPNYLQGWQRALAIAAGEVA"
     gene            complement(56226..57476)
                     /gene="wzxE"
                     /locus_tag="RHX21_000664"
     CDS             complement(56226..57476)
                     /gene="wzxE"
                     /locus_tag="RHX21_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid III flippase WzxE"
                     /protein_id="HDV1985898.1"
                     /translation="MSLAKASLWTAASTLVKIGAGLLVGKLLAVSFGPAGLGLAANFR
                     QLITVLGVLAGAGIFNGVTKYVAQYHDNPQQLRRVVGTSSAMVLGFSTLMALVFVLAA
                     APISQGLFGNTDYQGLVRLVALVQMGIAWGNLLLALMKGFRDAAGNALSLIVGSLIGV
                     LAYYVSYRLGGYEGALLGLALIPALVVIPAAIMLIKRGVIPLSYLKPSWDNGLAGQLS
                     KFTLMALITSVTLPVAYIMMRKLLAAQYSWDEVGIWQGVSSISDAYLQFITASFSVYL
                     LPTLSRLTEKRDITREVVKSLKFVLPAVAAASFTVWLLRDFAIWLLLSNKFTAMRDLF
                     AWQLVGDVLKVGAYVFGYLVIAKASLRFYILAEVSQFTLLMVFAHWLIPAHGALGAAQ
                     AYMATYIVYFSLCCGVFLLWRRRA"
     gene            complement(57478..58608)
                     /gene="rffA"
                     /locus_tag="RHX21_000665"
                     /gene_synonym="fcnA"
                     /gene_synonym="wecE"
     CDS             complement(57478..58608)
                     /gene="rffA"
                     /locus_tag="RHX21_000665"
                     /gene_synonym="fcnA"
                     /gene_synonym="wecE"
                     /EC_number="2.6.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-amino-4,6-dideoxygalactose transaminase"
                     /protein_id="HDV1985899.1"
                     /translation="MIPFNAPPVVGTELDYMQSAMGSGKLCGDGGFTRRCQQWLEQRF
                     GSAKVLLTPSCTASLEMAALLLDIQPGDEVIMPSYTFVSTANAFVLRGAKIVFVDVRP
                     DTMNIDETLIEAAITDKTRVIVPVHYAGVACEMDTIMALAKKHNLFVVEDAAQGVMST
                     YKGRALGTIGHIGCFSFHETKNYTAGGEGGATLINDKALIERAEIIREKGTNRSQFFR
                     GQVDKYTWRDIGSSYLMSDLQAAYLWAQLEAADRINQQRLALWQNYYDALAPLAKAGR
                     IELPSIPDGCVQNAHMFYIKLRDIDDRSALINFLKEAEIMAVFHYIPLHGCPAGEHFG
                     EFHGEDRYTTKESERLLRLPLFYNLSPVNQRTVIATLLNYFS"
     gene            complement(58613..59287)
                     /gene="rffC"
                     /locus_tag="RHX21_000666"
                     /gene_synonym="wecD"
     CDS             complement(58613..59287)
                     /gene="rffC"
                     /locus_tag="RHX21_000666"
                     /gene_synonym="wecD"
                     /EC_number="2.3.1.210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026256.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-amino-4,6-dideoxy-D-galactose
                     acyltransferase"
                     /protein_id="HDV1985900.1"
                     /translation="MPVRASIEPLTWENAFFGVNSAIVRITSEAPLLTPDALAPWSRV
                     QAKIAASNTGELDALQQLGFSLVEGEVDLALPVNNASDSGAVVAQETDIPALRQLASA
                     AFAQSRFRAPWYAPDASSRFYAQWIENAVRGTFDHQCLILRAASGDIRGYVSLRELNA
                     TDARIGLLAGRGAGAELMQTALNWAYARGKTTLRVATQMGNTAALKRYIQSGANVEST
                     AYWLYR"
     gene            complement(59265..60146)
                     /gene="rfbA"
                     /locus_tag="RHX21_000667"
     CDS             complement(59265..60146)
                     /gene="rfbA"
                     /locus_tag="RHX21_000667"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HDV1985901.1"
                     /translation="MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLA
                     GIREILIITTPEDKGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPS
                     CLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEK
                     PKQPKSNWAVTGLYFYDSKVVEYAKQVKPSERGELEITSINQMYLEAGNLTVELLGRG
                     FAWLDTGTHDSLIEASTFVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKT
                     GYGQYLLELLRARPRQY"
     gene            complement(60165..61232)
                     /gene="rffG"
                     /locus_tag="RHX21_000668"
     CDS             complement(60165..61232)
                     /gene="rffG"
                     /locus_tag="RHX21_000668"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HDV1985902.1"
                     /translation="MRKILITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSL
                     APVAQSERFAFEKVDICDRAELARVFTEHQPDCVMHLAAESHVDRSIDGPAAFIETNI
                     VGTYTLLEAARAYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPY
                     SASKASSDHLVRAWLRTYGLPTLITNCSNNYGPYHFPEKLIPLMILNALAGKSLPVYG
                     NGQQIRDWLYVEDHARALYCVATTGKVGETYNIGGHNERKNLDVVETICELLEELAPN
                     KPHGVVHYSDLITFVADRPGHDLRYAIDASKIARELGWLPQETFESGMRKTVQWYLAN
                     ESWWKQVQDGSYQGERLGLKG"
     gene            complement(61232..62494)
                     /gene="wecC"
                     /locus_tag="RHX21_000669"
     CDS             complement(61232..62494)
                     /gene="wecC"
                     /locus_tag="RHX21_000669"
                     /EC_number="1.1.1.336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetyl-D-mannosamine dehydrogenase"
                     /protein_id="HDV1985903.1"
                     /translation="MSFATISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDTINR
                     GEIHIVEPDLASVVKTAVEGGFLRASTTPVEADAWLIAVPTPFKGDHEPDMTYVESAA
                     RSIAPVLKKGALVILESTSPVGSTEKMAEWLAEMRPDLTFPQQVGEQADVNIAYCPER
                     VLPGQVMVELIKNDRVIGGMTPVCSARASELYKIFLEGECVVTNSRTAEMCKLTENSF
                     RDVNIAFANELSLICADQGINVWELIRLANRHPRVNILQPGPGVGGHCIAVDPWFIVA
                     QNPQQARLIRTAREVNDHKPFWVIDQVKAAVADCLAATDKRASELKIACFGLAFKPNI
                     DDLRESPAMEIAELIAQWHSGETLVVEPNIHQLPKKLTGLCTLAQLDEALATADVLVM
                     LVDHSQFKVINGDNVHQQYVVDAKGVWR"
     gene            complement(62491..63621)
                     /gene="wecB"
                     /locus_tag="RHX21_000670"
     CDS             complement(62491..63621)
                     /gene="wecB"
                     /locus_tag="RHX21_000670"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HDV1985904.1"
                     /translation="MKVLTVFGTRPEAIKMAPLVHALAKDPFFEAKVCVTAQHREMLD
                     QVLKLFSIVPDYDLNIMQPGQGLTEITCRILEGLKPILAEFKPDVVLVHGDTTTTLAT
                     SLAAFYQRIPVGHVEAGLRTGDLYSPWPEEANRTLTGHLAMYHFSPTETSRQNLLREN
                     VADSRIFITGNTVIDALLWVRDQVMSSDTLRSELAANYPFIDPDKKMILVTGHRRESF
                     GRGFEEICHALADIATTHQDIQIVYPVHLNPNVREPVNRILGHVKNVILIDPQEYLPF
                     VWLMNHAWLILTDSGGIQEEAPSLGKPVLVMRDTTERPEAVTAGTVRLVGTDKQRIVE
                     EVTRLLKDENEYQAMSRAHNPYGDGQACSRILEALKNNRISL"
     gene            complement(63677..64723)
                     /gene="wzzE"
                     /locus_tag="RHX21_000671"
     CDS             complement(63677..64723)
                     /gene="wzzE"
                     /locus_tag="RHX21_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709589.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECA polysaccharide chain length modulation
                     protein"
                     /protein_id="HDV1985905.1"
                     /translation="MTQPMPGKPAEDAENELDIRGLFRTLWAGKLWIIGMGLAFALIA
                     LAYTFFARQEWSSTAITDRPTVNMLGGYYSQQQFLRNLDVRSNMASADQPSVMDEAYK
                     EFVMQLASWDTRREFWLQTDYYKQRMVGNSKADAALLDEMINNIQFIPGDFTRAVNDS
                     VKLIAETAPDANNLLRQYVAFASQRAASHLNDELKGAWAARTIQMKAQVKRQEEVAKA
                     IYDRRMNSIEQALKIAEQHNISRSATDVPAEELPDSEMFLLGRPMLQARLENLQAVGP
                     AFDLDYDQNRAMLNTLNVGPTLDPRFQTYRYLRTPEEPVKRDSPRRAFLMIMWGIVGG
                     LIGAGVALTRRCSK"
     gene            complement(64735..65838)
                     /gene="wecA"
                     /locus_tag="RHX21_000672"
     CDS             complement(64735..65838)
                     /gene="wecA"
                     /locus_tag="RHX21_000672"
                     /EC_number="2.7.8.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--undecaprenyl-phosphate
                     N-acetylglucosaminephosphotransferase"
                     /protein_id="HDV1985906.1"
                     /translation="MNLLTVSTDLISIFLFTTLFLFFARKVAKKVGLVDKPNFRKRHQ
                     GLIPLVGGISVYAGICFTFGIVDYYIPHASLYLACAGVLVFIGALDDRFDISVKIRAT
                     IQAAVGIVMMVFGNLYLSSLGYIFGSWEMVLGPFGYFLTLFAVWAAINAFNMVDGIDG
                     LLGGLSCVSFAAIGMILWFDGQTSLAIWCFAMIAAILPYIMLNLGILGRRYKVFMGDA
                     GSTLIGFTVIWILLETTQGKTHPISPVTALWIIAIPLMDMVAIMYRRLRKGMSPFSPD
                     RQHIHHLIMRAGFTSRQAFVLITLAAALLASIGLLAEYSHFVPEWVMLVLFLLAFFLY
                     GYCIKRAWKVARFIKRVKRRLRRNRGGSPNLTK"
     gene            complement(66078..67337)
                     /gene="rho"
                     /locus_tag="RHX21_000673"
     CDS             complement(66078..67337)
                     /gene="rho"
                     /locus_tag="RHX21_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017492510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HDV1985907.1"
                     /translation="MNLTELKNTPVSELITLGENMGLENLARMRKQDIIFAILKQHAK
                     SGEDIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIR
                     PPKEGERYFALLKVNEVNFDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTAR
                     VLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTE
                     MQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNT
                     VVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEE
                     FKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGE
                     IDAMEFLINKLAMTKTNDDFFEMMKRS"
     gene            complement(67422..67523)
                     /gene="rhoL"
                     /locus_tag="RHX21_000674"
     CDS             complement(67422..67523)
                     /gene="rhoL"
                     /locus_tag="RHX21_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rho operon leader peptide RhoL"
                     /protein_id="HDV1985908.1"
                     /translation="MRSEQISGSSLNPSCRFSSAYSPVTRQRKDMSR"
     gene            complement(67664..67993)
                     /gene="trxA"
                     /locus_tag="RHX21_000675"
     CDS             complement(67664..67993)
                     /gene="trxA"
                     /locus_tag="RHX21_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017375425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxA"
                     /protein_id="HDV1985909.1"
                     /translation="MSDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILD
                     EIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKE
                     FLDANLA"
     gene            68124..69389
                     /gene="rhlB"
                     /locus_tag="RHX21_000676"
     CDS             68124..69389
                     /gene="rhlB"
                     /locus_tag="RHX21_000676"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase RhlB"
                     /protein_id="HDV1985910.1"
                     /translation="MSKTHLTEQKFSDFALHPKVVEALEKKGFHNCTPIQALALPLTL
                     AGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIADRKVNQPRALIMAPTRELAVQIHA
                     DAEPLAEATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQ
                     VVVLDEADRMYDLGFIKDIRWLFRRMPPANQRLNMLFSATLSYRVRELAFEQMNNAEY
                     IEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEEIWGHL
                     AADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLP
                     DDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIETYIGHSIPVSKYNPDALMTD
                     LPKPLRLTRPRTGNGPRRTGAPRNRRRSG"
     gene            69523..71007
                     /gene="gppA"
                     /locus_tag="RHX21_000677"
     CDS             69523..71007
                     /gene="gppA"
                     /locus_tag="RHX21_000677"
                     /EC_number="3.6.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanosine-5'-triphosphate,3'-diphosphate
                     diphosphatase"
                     /protein_id="HDV1985911.1"
                     /translation="MGSTSSLYAAIDLGSNSFHMLVVREVAGSIQTLTRIKRKVRLAA
                     GLNSENALSNEAMERGWQCLRLFAERLQDIPPSQIRVVATATLRLAVNAGDFIAKAQE
                     ILGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSL
                     SMGCVTWLERYFADRNLGQENFDAAEKAAREVLRPVADELRYHGWKVCVGASGTVQAL
                     QEIMMAQGMDERITLEKLQQLKQRAIHCGRLEELEIDGLTLERALVFPSGLAILIAIF
                     TELNIQCMTLAGGALREGLVYGMLHLTVEQDIRSRTLRNIQRRFMIDIDQAQRVAKVA
                     ANFFDQVEKEWHLEAISRDLLISACQLHEIGLSVDFKQAPQHAAYLVRNLDLPGFTPA
                     QKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAIIFASRRRDDLVPEMT
                     LQANHELLTLTLPQGWLTQHPLGKEIIAQESQWQSYVHWSLEVH"
     gene            complement(71054..73075)
                     /gene="rep"
                     /locus_tag="RHX21_000678"
     CDS             complement(71054..73075)
                     /gene="rep"
                     /locus_tag="RHX21_000678"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase Rep"
                     /protein_id="HDV1985912.1"
                     /translation="MRLNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCG
                     YQARHIAAVTFTNKAAREMKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMK
                     ANFSLFDDTDQLALLKELTEGLIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGER
                     DRIFAHCYGLYDAHLKACNVLDFDDLILLPTLLLQRNEEVRERWQNKIRYLLVDEYQD
                     TNTSQYELVKLLVGSRARFTVVGDDDQSIYSWRGARPQNLVLLSQDFPALKVIKLEQN
                     YRSSGRILKAANILIANNPHVFEKRLFSELGYGTELKVLSANNEEHEAERVTGELIAH
                     HFVNKTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRV
                     LTNPDDDSAFLRIVNTPKREIGPATLKKLGEWAMTRNKSMFTASFDMGLSQTLSGRGY
                     EALTRFTHWLAEIQRLAEREPIAAVRDLIHGMDYESWLYETSPSPKAAEMRMKNVNQL
                     FSWMTEMLEGSELDEPMTLTQVVTRFTLRDMMERGESEEELDQVQLMTLHASKGLEFP
                     YVYMVGMEEGFLPHQSSIDEDNIDEERRLAYVGITRAQKELTFTLCKERRQYGELVRP
                     EPSRFLLELPQDDLIWEQERKVVSAEERMQKGQSHLANLKAMMAAKRGK"
     gene            73292..73740
                     /locus_tag="RHX21_000679"
                     /pseudo
     CDS             73292..73740
                     /locus_tag="RHX21_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312737.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
     gene            73939..74220
                     /gene="ppiC"
                     /locus_tag="RHX21_000680"
     CDS             73939..74220
                     /gene="ppiC"
                     /locus_tag="RHX21_000680"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004097481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PpiC"
                     /protein_id="HDV1985913.1"
                     /translation="MAKTAAALHILVKEEKLALDLLEQIKNGADFGKLAKKHSICPSG
                     KRGGDLGEFRQGQMVPAFDKVVFSCPVLEPTGPLHTQFGYHIIKVLYRN"
     gene            complement(74307..75782)
                     /gene="ilvC"
                     /locus_tag="RHX21_000681"
     CDS             complement(74307..75782)
                     /gene="ilvC"
                     /locus_tag="RHX21_000681"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HDV1985914.1"
                     /translation="MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVG
                     CGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLV
                     INLTPDKQHSDVVRTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTE
                     VREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDL
                     MGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDR
                     LSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREET
                     GKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLH
                     ELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPE
                     GAVDNAQLRDVNEAIRCHAIEQVGKKLRGYMTDMKRIAVAG"
     gene            75932..76825
                     /gene="ilvY"
                     /locus_tag="RHX21_000682"
     CDS             75932..76825
                     /gene="ilvY"
                     /locus_tag="RHX21_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator IlvY"
                     /protein_id="HDV1985915.1"
                     /translation="MDLRDLKTFLHLAESRHFGRSARAMHVSPSTLSRQIQRLEEDLG
                     QPLFVRDNRTVTLTEAGEELRVFAQQTLLQYQQLRHTIDQQGPSLSGELHIFCSVTAA
                     YSHLPPILDRFRAEHPSVEIKLTTGDAADAMEKVVTGEADLAIAGKPETLPGAVAFSM
                     LENLAVVLIAPALPCPVRNQVSVEKPDWSTVPFIMADQGPVRRRIELWFRRNKISNPM
                     IYATVGGHEAMVSMVALGCGVALLPEVVLENSPEPVRNRVMILERSDEKTPFELGVCA
                     QKKRLHEPLIEAFWKILPNHK"
     gene            complement(76877..78421)
                     /gene="ilvA"
                     /locus_tag="RHX21_000683"
     CDS             complement(76877..78421)
                     /gene="ilvA"
                     /locus_tag="RHX21_000683"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase, biosynthetic"
                     /protein_id="HDV1985916.1"
                     /translation="MADSQPLSGAPEGAEYLRAVLRAPVYEAAQVTPLQKMEKLSSRL
                     DNVILVKREDRQPVHSFKLRGAYAMMAGLTEEQKAHGVITASAGNHAQGVAFSSARLG
                     VKALIVMPTATADIKVDAVRGFGGEVLLHGANFDEAKAKAIELSQQQGFTWVPPFDHP
                     MVIAGQGTLALELLQQDAHLDRVFVPVGGGGLAAGVAVLIKQLMPQIKVIAVEAEDSA
                     CLKAALDAGHPVDLPRVGLFAEGVAVKRIGDETFRLCQEYLDDIITVDSDAICAAMKD
                     LFEDVRAVAEPSGALALAGMKKYIALHNIRGERLAHILSGANVNFHGLRYVSERCELG
                     EQREALLAVTIPEEKGSFLKFCQLLGGRSVTEFNYRFADAKNACIFVGVRLSRGLEER
                     KEILQMLNDGGYSVVDLSDDEMAKLHVRYMVGGRPSHPLQERLYSFEFPESPGALLRF
                     LNTLGTYWNISLFHYRSHGTDYGRVLAAFELGDHEPDFETRLNELGYDCHDETNNPAF
                     RFFLAG"
     gene            complement(78424..80274)
                     /gene="ilvD"
                     /locus_tag="RHX21_000684"
     CDS             complement(78424..80274)
                     /gene="ilvD"
                     /locus_tag="RHX21_000684"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HDV1985917.1"
                     /translation="MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFT
                     QFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIAD
                     SVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQII
                     KLDLVDAMIQGADPKVSDSQSDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGN
                     GSLLATHADRKQLFLNAGKRIVELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMG
                     GSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIG
                     ILGELDRAGLLNRDVKNVLGLTLPQTLEQYDVMLTQDDAVKNMFRAGPAGIRTTQAFS
                     QDCRWDTLDDDRANGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTG
                     PAKVYESQDDAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKAC
                     ALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIEDGDLIAIDIPNRGIQLQVSDAELA
                     ARREAQDARGDKAWTPKNRERQVSFALRAYASLATSADKGAVRDKSKLGG"
     gene            complement(80339..81268)
                     /gene="ilvE"
                     /locus_tag="RHX21_000685"
     CDS             complement(80339..81268)
                     /gene="ilvE"
                     /locus_tag="RHX21_000685"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain-amino-acid transaminase"
                     /protein_id="HDV1985918.1"
                     /translation="MTTKKADYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYD
                     SHKGPVVFRHREHMQRLHDSAKIYRFPVSQSIDELMEACRDVIRKNNLTSAYIRPLIF
                     VGDVGMGVNPPAGYSTDVIIAAFPWGAYLGAEALEQGIDAMVSSWNRAAPNTIPTAAK
                     AGGNYLSSLLVGSEARRHGYQEGIALDVNGYISEGAGENLFEVKDGVLFTPPFTSSAL
                     PGITRDAIIKLAKELGIEVREQVLSRESLYLADEVFMSGTAAEITPVRSVDGIQVGEG
                     RCGPVTKRIQQAFFGLFTGETEDKWGWLDQVNQ"
     gene            complement(81288..81551)
                     /gene="ilvM"
                     /locus_tag="RHX21_000686"
     CDS             complement(81288..81551)
                     /gene="ilvM"
                     /locus_tag="RHX21_000686"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 2 small subunit"
                     /protein_id="HDV1985919.1"
                     /translation="MMQHQVNVSARFNPETLERVLRVVRHRGFHVCSMNMAAASDAQN
                     INIELTVASPRSVDLLFSQLNKLVDVAHVAICQSTTTSQQIRA"
     gene            complement(81548..83194)
                     /locus_tag="RHX21_000687"
     CDS             complement(81548..83194)
                     /locus_tag="RHX21_000687"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 2 catalytic subunit"
                     /protein_id="HDV1985920.1"
                     /translation="MNGAQWVVHALRAQGVNTVFGYPGGAIMPVYDALYDGGVEHLLC
                     RHEQGAAMAAIGYARATGKTGVCIATSGPGATNLITGLADALLDSIPVVAITGQVSAP
                     FIGTDAFQEVDVLGLSLACTKHSFLVQSLEELPRIMAEAFDVACSGRPGPVLVDIPKD
                     IQLASGDLEPWFTTVENEVTFPHAEVEQARQMLAKAQKPMLYVGGGVGMAQAVPALRE
                     FLAATKMPATCTLKGLGAVEADYPYYLGMLGMHGTKAANFAVQECDLLIAVGARFDDR
                     VTGKLNTFAPHASVIHMDIDPAEMNKLRQAHVALQGDLNALLPALQQPLNINDWQQHC
                     AQLRDEHSWRYDHPGDAIYAPLLLKQLSDRKPADCVVTTDVGQHQMWAAQHIAHTRPE
                     NFITSSGLGTMGFGLPAAVGAQVARPNDTVVCISGDGSFMMNVQELGTVKRKQLPLKI
                     VLLDNQRLGMVRQWQQLFFQERYSETTLTDNPDFLMLASAFGIPGQHITRKDQVEAAL
                     DTMLNSDGPYLLHVSIDELENVWPLVPPGASNSEMLEKLS"
     gene            complement(83197..83247)
                     /locus_tag="RHX21_000688"
     CDS             complement(83197..83247)
                     /locus_tag="RHX21_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1985921.1"
                     /translation="MNNSTKFCFSRFRTGN"
     gene            complement(83334..83432)
                     /gene="ilvL"
                     /locus_tag="RHX21_000689"
     CDS             complement(83334..83432)
                     /gene="ilvL"
                     /locus_tag="RHX21_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ilv operon leader peptide"
                     /protein_id="HDV1985922.1"
                     /translation="MTALLRVISLVVISVVVIIIPPCGAALGRGKA"
BASE COUNT        20176 a        22804 c        21260 g        19337 t
ORIGIN      
        1 gcggggtgtg cataatacgc tttcccgcta cagagtcaag catttatttt tgctttctct
       61 gccggagttc tcaggagaac cccgctgacc cggcggcgtg tttgccgttg ttccgtgtca
      121 gtggtgccgc attataggga gttattccgg cctgacaaga ggaaatttaa aataattttc
      181 tgaccgcgca ttttttattc tttatgctta tttcagcgtc ggtttgtcgg ttaaatgggc
      241 gatttctcgg gcgaaattcg ccacctgctc ccaatcggta tagacaactt ctttgcgcgt
      301 atccgtttca ccgcctgaca tcttcataat cagcttgatc ataaaacggt cgtaccagcg
      361 ataacgtggg taacgcagcg ccccggcaat gaccgcgcag cgatcgggac gccattgcga
      421 gttcatcaga aacttgcgcg cgtagctgtt ggtctgtgga gtacgcttct ccggtttgcg
      481 cgccaccaga ttcacggagt aaaaggcgct cggcatcgaa ttcagccgcg tcgcatgttt
      541 tttgacaaat tcctggaacg ctgaatggta gtgaccatag cgaatagaag caccaatgac
      601 cacacggtca tagttttccc actgtggttc ttcaatgcgg tgcacattgg cgacatccgc
      661 ctggatcccc agttctttca gttccgaagc caggtaggag gcaatctcgc gcgtttgtcc
      721 gtcccttgtt gagaaaagaa ttaatgtttt cacgtattac tccatcattc acgccagaaa
      781 gtcggggtaa agagcaccag caatgtaaag acctcgagac gaccaaacag catgttggca
      841 atcaggatcc atttagccac cgggttcata ctggtaaagt tatcagcaac cacgccaagc
      901 cctggcccca ggttattcaa tgtcgcaaca accgacgcaa aggcagaaaa gtcatccacg
      961 cccgtggcga taatcgccag catactgaca ataaacacca atgcataggc ggagaaaaat
     1021 ccccaaacgg cttcgaggat acgttccggc agtgcgcgat tccccagctt aatgctatag
     1081 acggcgttcg gatgcaccag tcgtttcagc tcacggttcc cctgcttaaa cagcagcagg
     1141 atgcggatca ccttcaggcc accgcccgtt gacccggcgc aaccgccgat aaaggctgaa
     1201 cataaaagca gtaccggcaa aaagagcggc cagcgggcaa tgctgtcagt tgtaaacccg
     1261 gcggttgtcg ccatcgacac cacctggaaa aacgcctggt taattgtcat cagcgccgaa
     1321 ctgtagacat tatgaaacca cagtacgagg gtacaaataa ccaccagcgt aaactgtacg
     1381 ccgataaaca tgcgaaattc cggatcgcgc caataaacct tcagactacg cccacttaac
     1441 agtgaaaagt gcagaccgta gttacagccg gagatcagca ggaagatagc aatgatagtg
     1501 ttaatagtcg ggctatcgaa ataaccgata ctggcatcat gtgtcgagaa gccgccaata
     1561 gcgatagtcg caaagctatg gccgatggca tcaaaggcat ccattccggc aaaccacaac
     1621 gccagcgcac aggcgacggt cagcaagaca taaatcaacc acagggtttt cgccgtttcc
     1681 gcaattcgcg ggcgcatttt gttatctttc agcgggccgg gcatttctgc gcgatagagc
     1741 tgcatcccac ccacgccgag gataggcagt atcgcaaccg ccaacacgat gatccccatc
     1801 ccgccaaacc attgcagcat ctggcgataa aagaggatgg cgtgagggag cgaatccagc
     1861 cccaccagcg tagtggctcc cgtagtggtc aggccagaga aagattcaaa aaacgcatcg
     1921 gtaatcgtga ggttcgggct ttccgagaag ataaaaggga gcgcaccgac gctacccagc
     1981 acggtccaga acagcaccac tatcagaaac ccctcacggg atttaagttc gcctttctct
     2041 ttgcggttcg gccaccacag catagagcca atggcgaggg cgacaaaaaa ggtctgggta
     2101 aaagcgcggc ccgctccatc ccggtagatg agtgctacca gcccagggat aatcatggtc
     2161 cctgaaaata agatgaccag tagtccaacg attcgggtaa tggcgcgaaa atgcatctct
     2221 gccgcttcct tagttctgca aaacgaagtg gggattattc ttcaatcgct aacaattgca
     2281 atgaaccacg gctaaaatcc gccagctttg cggaaaattc agccactttc gccgccggaa
     2341 gcgccacccg cagcagaacg aatgcctgat aatcactgtt gataattttg ccgtcacact
     2401 gccccagcaa cgcttcaatg ccggttaact gatgatattc acattgcaaa gtatattcgg
     2461 ttaatggcgt cttgcgttgg gtcgttagct ggcgcagcgc ctgattcacg ccgccgccat
     2521 acgctttcac taacccaccg gtgccaagca atatgccgcc gtagtagcgc actaccacag
     2581 cggtaatttc cccgacgccg ctgcccatta gctgggcgag catcggttta cctgccgttc
     2641 ccgccggctc cccgtcgtca gagaaaccca gctgttgaga atcatccggc gcacccgcga
     2701 cccacgccac gcaatggtgc cgggcatcgg ggtgttctgc ccgcaccgat tcaacaaacg
     2761 ctttcgccgc ctcaacgcca tcggtatgcg ccaacatcgt tatgaagcgg ctctttttga
     2821 tctcttcaac gaccgtgacc ggtgccgcag gaattaacca gctttccatc acgccagttt
     2881 cagatcccgg gtcatgtttt ccacgttgtt ttcgtggatc accacgttgt cttcgatacg
     2941 aatgccgccg aacggtttca gtgcttcaat tttctgccag ttgaagtgct tgctgaactg
     3001 cccttcacgc cacggtgcca gtagcgattc gatgaagtag atacccggtt cgatggttaa
     3061 caccatgccc ggctggagaa tacgggtgca gcgcaggtac ggatattttg ccggtgccgc
     3121 gaggtgcgta ccgctatcat cctgcataaa accagcgacg tcatgcacct gcaggcccag
     3181 cggatggccg ataccatgcg gcataaacgg cccggtaaga tcgttttcga ccatcgcttc
     3241 ttcactcata tcggtgatga tttgatgttt acgcagcagt ttggcgatgc gctgatggaa
     3301 ctggatgtgg taatccacat agctgacgcc tgctttcatg gtggcgatca gcgccagttg
     3361 ttcatcatta acgtccttca ccagctgcgc gtagtcgttg tcactttttg ccgaccaggt
     3421 acgggtcagg tcagccgcat agccgttata ttctgccccg gcatccagca ggaagctgcg
     3481 catctcttcc ggtgcctgat ggtccagttt ggtgtaatgc agtaccgcag cgtgttcgtt
     3541 aagcgccaca atgttgctgt aaggtacgtc ggtatcacga tgaccggtcg cggtcagata
     3601 ggcaatgttg atatcgaact cgctcatgcc agaacggaac gcttcttctg ccgcgcggtg
     3661 accgttgacc gccattttct gcgcttcacg catacaggcc agttcgtact cagttttgaa
     3721 ggagcgatag taatgcaggt agtcgataac ccctttcggg ttgatgttgc tggcctcaat
     3781 acccagttgc agcgcacgtt ccggcaccgg accgatataa ccgatattgc cgcgcgcagc
     3841 aggcagcagg ctaccaatgc catcggcttt cggcagcgcg atcacttcca catcttcagt
     3901 ccagaaagag gtcggcagcg gttcgacgtt gtgccagtaa tcaaccggca gatagaacca
     3961 cagtttcggc ttgttcacgc catccaccag caaccagcag tttggcacct gagttaccgg
     4021 cacccacgct ttgaattgcg ggttcacttt aaacggatag ggatgatcgt cgagaaaaac
     4081 attgaacagc tcgccggagt gaataagtaa cgcatccagc ttgaagcgcg ccagcgcatc
     4141 gcgagtccgt tcttgtaagg tagctatatg atttttatag agcgaggcca gtgattccat
     4201 tttttaccct tctgtttttt tgaccttaag tctccgcatc ttagcacatc gttcatccag
     4261 agcgtgattt ctgccgagcg tgatcagatc ggcatttctt taatcttttg tttgcatatt
     4321 tttaacacaa aatacacact tcgactcatc tggtacgacc agattacctt gcggattcag
     4381 gagactgaca tgctttacaa aggcgacacc ctgtaccttg actggctgga agatggcatt
     4441 gccgaactgg tatttgatgc cccaggttca gttaataaac tcgacactgc gaccgtcgcc
     4501 agcctcggcg aggccatcgg cgtgctggaa cagcaatcag atctaaaagg gctgctgctg
     4561 cgttcgaaca aagcagcctt tatcgtcggt gctgatatca ccgaattttt gtccctgttc
     4621 ctcgttcctg aagaacagtt aagtcagtgg ctgcactttg ccaatagcgt gtttaatcgc
     4681 ctggaagatc tgccggtgcc gaccattgct gccgtcaatg gctatgcgct gggcggtggc
     4741 tgcgaatgcg tgctggcgac cgattatcgt ctggcgacgc cggatctgcg catcggtctg
     4801 ccggaaacca aactgggcat catgcctggc tttggcggtt ctgtacgtat gccacgtatg
     4861 ctgggcgctg acagtgcgct ggaaatcatt gccgccggta aagatgtcgg cgcggatcag
     4921 gcgctgaaaa tcggtctggt ggatggcgta gtcaaagcag aaaaactggt tgaaggcgca
     4981 aaggcggttt tacgccaggc cattaacggc gacctcgact ggaaagcaaa acgtcagccg
     5041 aagctggaac cactaaaact gagcaagatt gaagccacca tgagcttcac catcgctaaa
     5101 gggatggtcg cacaaacagc ggggaaacat tatccggccc ccatcaccgc agtaaaaacc
     5161 attgaagctg cggcccgttt tggtcgtgaa gaagccttaa acctggaaaa caaaagtttt
     5221 gtcccgctgg cgcataccaa cgaagcccgc gcactggtcg gcattttcct taacgatcaa
     5281 tatgtaaaag gcaaagcgaa gaaactcacc aaagacgttg aaaccccgaa acaggccgcg
     5341 gtgctgggtg caggcattat gggcggcggc atcgcttacc agtctgcgtg gaaaggcgtg
     5401 ccggttgtca tgaaagatat caacgacaag tcgttaaccc tcggcatgac cgaagccgcg
     5461 aaactgctga acaagcagct tgagcgcggc aagatcgatg gtctgaaact ggctggcgtg
     5521 atctccacaa tccacccaac gctcgactac gccggatttg accgcgtgga tattgtggta
     5581 gaagcggttg ttgaaaaccc gaaagtgaaa aaagccgtac tggcagaaac cgaacaaaaa
     5641 gtacgccagg ataccgtgct ggcgtctaac acttcaacca ttcctatcag cgaactggcc
     5701 aacgcgctgg aacgcccgga aaacttctgc gggatgcact tctttaaccc ggtccaccga
     5761 atgccgttgg tagaaattat tcgcggcgag aaaagctccg acgaaaccat cgcgaaagtt
     5821 gtcgcctggg cgagcaagat gggcaagacg ccgattgtgg ttaacgactg ccccggcttc
     5881 tttgttaacc gcgtgctgtt cccgtatttc gccggtttca gccagctgct gcgcgacggc
     5941 gcggatttcc gcaagatcga caaagtgatg gaaaaacagt ttggctggcc gatgggcccg
     6001 gcatatctgc tggacgttgt gggcattgat accgcgcatc acgctcaggc tgtcatggca
     6061 gcaggcttcc cgcagcggat gcagaaagat taccgcgatg ccatcgacgc gctgtttgat
     6121 gccaaccgct ttggtcagaa gaacggcctc ggtttctggc gttataaaga agacagcaaa
     6181 ggtaagccga agaaagaaga agacgccgcc gttgaagacc tgctggcaga agtgagccag
     6241 ccgaagcgcg atttcagcga agaagagatt atcgcccgca tgatgatccc gatggtcaac
     6301 gaagtggtgc gctgtctgga ggaaggcatt atcgccactc cggcggaagc ggatatggcg
     6361 ctggtctacg gcctgggctt ccctccgttc cacggcggcg cgttccgctg gctggacacc
     6421 ctcggtagcg caaaatacct cgatatggca cagcaatatc agcacctcgg cccgctgtat
     6481 gaagtgccgg aaggtctgcg taataaagcg cgtcataacg aaccgtacta tcctccggtt
     6541 gagccagccc gtccggttgg cgacctgaaa acggcttaag gagtcacaat ggaacaggtt
     6601 gtcattgtcg atgcaattcg caccccgatg ggccgttcga agggcggtgc ttttcgtaac
     6661 gtgcgtgcag aagatctctc cgctcattta atgcgtagcc tgctggcgcg taacccggcg
     6721 ctggaagcgg cggccctcga cgatatttac tggggttgtg tgcagcagac gctggagcag
     6781 ggttttaata tcgcccgtaa cgcggcgctg ctggcagaag taccacactc tgtcccggcg
     6841 gttaccgtta atcgcttgtg tggttcatcc atgcaggcac tgcatgacgc agcacgaatg
     6901 atcatgactg gcgatgcgca ggcatgtctg gttggcggcg tggagcatat gggccatgtg
     6961 ccgatgagtc acggcgtcga ttttcacccc ggcctgagcc gcaatgtcgc caaagcggcg
     7021 ggcatgatgg gcttaacggc agaaatgctg gcgcgtatgc acggtatcag ccgtgaaatg
     7081 caggatgcct ttgccgcgcg gtcacacgcc cgcgcctggg ccgccacgca gtcggccgca
     7141 tttaaaaatg aaatcatccc gaccggtggt cacgatgccg acggcgtcct gaagcagttt
     7201 aattacgacg aagtgattcg cccggaaacc accgtggaag ccctcgccac gctgcgtccg
     7261 gcgtttgatc cagtaaacgg tatggtaacg gcgggcacat cttctgcact ttccgatggc
     7321 gcagctgcca tgctggtgat gagtgaaagc cgcgcccatg aattaggtct taagccgcgc
     7381 gctcgtgtgc gttcgatggc ggtcgttggt tgtgacccat cgattatggg ttacggcccg
     7441 gttccggcct cgaaactggc gctgaaaaaa gcggggcttt ctgccagcga tatcggcgtg
     7501 tttgaaatga acgaagcctt tgccgcgcag atcctgccat gtattaaaga tctgggacta
     7561 attgagcaga ttgacgagaa gatcaacctc aacggtggcg cgatcgcgct gggtcatccg
     7621 ctgggttgtt ccggtgcgcg tatcagcacc acgctgctga atctgatgga acgcaaagac
     7681 gttcagtttg gtctggcgac gatgtgtatc ggtctgggtc agggtattgc gacggtgttt
     7741 gagcgggttt aaccacttgc cggatgcggc gtgaacgcct tatccggtct accgatccgg
     7801 caccaatgta ggcctgataa gacgcgccag cgtcgcatca ggcatcatgc accaattgcc
     7861 ggatgcggcg taaacgcctt atccggccta cggttcggac tatttgtagg cacgataaga
     7921 cgcgacagcg tcgcatcggg catggtttgc cagatacgtc atagatctaa atgccactga
     7981 ataacagttt agttgccgtt cttcccgcct gtcaggggcg ggttttttta tatctcagat
     8041 aaatgcaaac gcatcgccaa acaggcgatc ttcccgcgca ttacgctcac tgcaaaacag
     8101 atcgcgggca attttcgcca tctcaaaacg tccggcaata tagatatcat gctctgccag
     8161 cgtaccgtga tcctgcaata ccgccgttaa cacggtgcca gtacgcccac gccagcccgc
     8221 ttccggttgt tcaaccaccg gcaccacttg cagaccagga tgcttcaacg aaagcgcctc
     8281 aagctcgcag agatcataca gatgctgctc ttcacgcccg ccccagtaaa tggtgatatc
     8341 acggtttggg ttacgcgcca acgctgtcag caaaatcgag cgggcataag agaacccggt
     8401 gccgcccgca atcaaaatca tcggacgctc ttcatcatcg cgcagccacg cttctccgtg
     8461 gggaatgtcg accacgattt gatgatcttt gaggatgcgg tccatgactg ctttcgcgta
     8521 aaggttgatt tcagaagcgc caatatgcag ctcgataaac cctttttcat ccggcgtcga
     8581 agccattgag aacggacgtt tgtcgcgctc atccatcact accatcaaat actgaccagc
     8641 acgaaaagaa aaggccgcgt ctggcacgat gcggacacga tatacggtat ccgtgatagc
     8701 ttctaccgag gtcactttac agcttaaggt tgtcatgcgc tttctctgtc ggatcgataa
     8761 atagggcaaa acaaacgcgc atcaggcgct tttaccgttg ttaaaaatag ccagttcatc
     8821 ccagatggcg tcaatatgcg cgacaacatc tggatctttt ttgatgggac gtccccattc
     8881 acgctgggtt tcccccggcc atttattcgt ggcatccagc cccatttttg aacccagccc
     8941 ggagacaggc gaggcaaaat ccagataatc aataggcgta ttttctacca gaacagtatc
     9001 ccgcgccggg tccatacggg tggtaatcgc ccaaatcaca tcgttccagt cgcgtgcgtt
     9061 aacgtcatca tcgcaaacga tcacaaattt agtgtacata aactggcgta agaacgacca
     9121 gacgcccatc atgacgcgct tcgcgtgtcc ggcgtactgt tttttgattg tcactaccgc
     9181 caggcgataa gagcagcctt ccggcggcag gtaaaaatcg acaatttccg ggaactgttt
     9241 ttgcagaatc ggcacaaaca cttcgttcag tgcgacaccc agcaccgcgg gctcatctgg
     9301 cggacgcccg gtataggtgg aatggtaaat cgcatcttca cgctgggtaa tatgcgtcac
     9361 ggtaaatacc gggaaactat cgacttcatt atagtaaccg gtgtggtcgc catacggccc
     9421 ttccggcgca gtttcgcctt gttcgatata cccttccagc acaatctccg cactggcggg
     9481 cacttcaaga tcattggaga tacacttcac cacttcggtc ttggtgccac gtagcaatcc
     9541 ggcaaacgca tactctgaaa gcgtatccgg aacgggagtg actgcaccga gaatcgtggc
     9601 gggatcggca cccagcgcca cagaaaccgg gaaacgttcg cccggatgcg ccgcacacca
     9661 ctcctgataa tccagcgcgc cgccgcgatg cgacagccag cgcataatca gtttgttttt
     9721 accaatcagc tgctggcgat aaatgcccag attctgccgc tctttatgtg ggccgcgcgt
     9781 cactgtcagc ccccaggtaa tcagcggcgc ggcatcttcc ggccagcagg tcataatggg
     9841 aatgcgattg agatcgacgt catcgccaga gacgattttt tgttggcagg gcgcaccacg
     9901 cagccgcttt gtcggcatgt tcaatacttg cttaaactgc ggcagtttat caaacaggtc
     9961 gcggaaacct tttggcggct ccggctcttt cagaaacgcc aataatttac caacttcacg
    10021 cagcgccgaa acatcttcct gccccatgcc catcgccacg cgctttggcg taccgaacag
    10081 gttgcacagc accggcattg agtagccttt agggttttcg aacaacagcg caggcccacc
    10141 ggcacgcaaa gtgcggtcag caatttcagt gatttccaga tgcggatcca ccgggagcgt
    10201 gatacgtttt agctcaccct gctgttcaag cagcgtcaag aagtcgcgta aatcgttata
    10261 tttcatggcg tccattgtag cctcttaatc tgcgcccatt atacggcgtt catctttgcg
    10321 atgctgtaaa tttgttaaat tagcgtgaac tctgacggta taacgcaaac cggggaatat
    10381 aattaactta gcgtaaagct tttgctatcc ttgcgccccg attaaacgga taagagtcat
    10441 tatgcaatcc tggtatttac tgtactgcaa gcgcgggcaa cttcaacgtg cccaggaaca
    10501 cctcgaaaga caggctgtga attgcctggc accgatgatc accctggaaa aaatcgtgcg
    10561 tggaaaacgt actgcagtca gtgagccatt gtttcccaac tacctgtttg tcgaatttga
    10621 tccagaagtg attcatacca cgactatcaa cgcgacccgc ggtgtcagtc acttcgtgcg
    10681 ctttggcgcg tcgccagcga tagtcccatc ggcggtgatt catcagctat cggtatataa
    10741 accgaaagac attgtcgatc cggcaacccc ttatccggga gataaggtga ttattaccga
    10801 aggcgcgttc gaaggctttc aggccatttt caccgaaccc gatggtgagg ctcgctccat
    10861 gctattgctt aatcttatta ataaagagat taagcacagt gtgaagaaca ccgagttccg
    10921 caaactctaa aacgcaatcc caaacagtgt tttgacatta gcatccgtgg tggcagccag
    10981 ccatgcggca tcttctccac gccagtgcgc aatacgttgc aaaatatggg gcagatgggc
    11041 tggctcgttg cgccgggatg atggctttgg cgtgagatcg cgagggagca gatacggcgc
    11101 atcagtttcg atcagtaatt tttccgccgg aatcaacggc aaaagttccc gcagctccag
    11161 tccgcgtcgt tcatcgcaaa cccaaccggt aatgccgata taaattccat gcgccacgca
    11221 cgcctgcatc tcttcgcgtg tgccggtaaa gcaatgaaga accgcaccag gcagtttatc
    11281 cagccacggc tccagcaatg tcataaaccg ctcgtgggca tcgcgacagt gcataaatac
    11341 cggcatgttt aaatctgcgg caatgcgtag ctgggcaaca aaagcgcgtt cctgctcttc
    11401 cggcgtcgaa aagttgcggt taaagtcgag accacattca ccaatcgcca ccacttctgg
    11461 ctgcgcggcc agctcaataa tcgcttcttc agtcgcagct tgccactggc tgctgtcgtg
    11521 aggatgtacg cccgccgttg accaacagga cgaatactga cgcgccagct tttgcgcctg
    11581 ctggctttca cgcaggttag tgccggtgat gagtagccca ttaactcccg cgtcaaaagc
    11641 gcgcgctaca acatcatcac ggtctttcgc aaattgcgaa ctggtcaaat taacgccgat
    11701 atcaaacatc ctgtactcca tatgacaacc gccctgacgg gcggttgaat ttattcttca
    11761 gttttttcgc tttctgcttc agcgtcgttt tcctcttccc gatttcgccc tttaccaacg
    11821 taaaagcgtg agaagaagac accgatttca aacagacagt acatcgggat cgccaacagc
    11881 gtttgcgaga agacatccgg cggcgtcagc aacatcccga caacgaatgc accaaccagc
    11941 acatacgggc gttttttgcg taagtcttct ggcgaggtaa tccccatcca gcacagcagc
    12001 acaattgcca ccggcacttc aaaggagaca ccaaacgcca taaacagcgc cataacgaag
    12061 cttaaatagc tggcgatgtc ggtggatacc tgcacccctt ccggcgcggt attggcaagg
    12121 aagccaaatg ccagcggaaa gaccacaaag taggcgaacg ccatgccgat ataaaacagc
    12181 agagagctgg aaaccagcag cggcaccacc aggcgacgtt catgcttata cagcgctggg
    12241 gcgataaatg cccacacctg atagagaatc accggcgctg acagaatcag cgacaccata
    12301 aaggtcagct tgatcggcgt aaagaacggc gaggccacgt cggtggcgat catcgttgaa
    12361 ccttgcggca actgcttgat caatggcgcg gataccaggt gatagatgtc attggcgaaa
    12421 tagaccagac acaggaatat cacgatcacc gcgataatgc agttcagcag acgcttacgc
    12481 agctcaatca gatgcgtgat aagcggttga gtatcttcta cagacatgtt tacggtttat
    12541 cactcgacga aggggaaggt gcagcggttt tcggttcagc gtccgcagca ggttttacca
    12601 ccggctctgg cgtggtttct ggcttctgtt ccggcgaact ggcctgcgtt tgtgcagcgg
    12661 caggcgttac gccctcatgc gcagcttcat tatctttcac caccgggtta tggatggtgt
    12721 gcgcttcatc gctcgccttt tcaggatcgt ttgcaacgta ggaacgcttc atcgactccg
    12781 cggcctggcg tagttcatcc atcgacgctt tcagttcggg tgtcaggtta gtgaggctcg
    12841 ccttttcaac ctttttcaga ctgtcctgaa actcctggag ttttaactcc tgggtcagtt
    12901 cgttctgcac cgttgtcgcc agtgaacgca acgagcgaat ccagcccgct accgttttta
    12961 ccgccacagg cagtcgttgc ggccccagaa cgacgaggcc gatgatgaac accaatagca
    13021 gttcgctaaa accgatatca aacacggatt acacctgctc tttatcgtgg cgcttcgcgt
    13081 cttctgtttt agcctgttcc tgattcgtat ccgcctgctt atcggcgata gttttcgcag
    13141 taaaatcagc atcctgactg gttttatcct gctttggttc atcatcgctc attgcttttt
    13201 taaagccttt gatcgacgca ccaagatcgg aaccgatgga gccgagcttt ttggtgccaa
    13261 aaagcagtac aacgatgacg gcaataatca ataactgcca aatactgata ccacccatac
    13321 atgttcctct gtggtagatg atgattaaac aaagccgcat tatacgttac acggcccgcc
    13381 ttgagcgatg aaaaaatcag cgtgttttgc gccaaccgac aaaccaggcg atcagaccac
    13441 ctgccattaa ccagccgggc atcagccccc attcaggtcg gctgaccaac aagaatgtgc
    13501 cacttaatac taacgtagcg ccaattccga gaaaataacg cgattgtccc tgacgtacat
    13561 gatttgactg aagctcgcgg gcaatcttat caacactgtg ctgtaaatac ttgccctggc
    13621 gcaaactgtc gtaaaccaat tcaggcagtt ctggcatttt ttcgacccag aacggcgctt
    13681 tttctttaaa tgctctcacc agcgcaggaa taccgacctg atctttaatc cacgactcca
    13741 ggaaaggctt cgctgttttc cataaatcga gctgcggata aagctggcgt cctacccctt
    13801 cgacatagag cagggttttc tggagtaaca ccagttgcgg ctgcacttcc atattgaagc
    13861 gacgcgccgt attaaacaga tttaacagta catgtccaaa cgaaatttcg gccagcggtt
    13921 tctcaaagat aggttcacag accgtacgaa tggcaaattc gaactcttca acgttggtat
    13981 ctggtggcac ccagcctgaa tcgacgtgta gctctgccac tttgcgatag tcgcgattaa
    14041 agaaggcgat aaagttttct gccagatagc gtttatcttc tttgtttagc gagccaacaa
    14101 tcccgcaatc aatgccgata tatttcgggt tttccgggtg ttcatagctt acgaagatgt
    14161 tgccagggtg catatcggca tggaaaaagc tgtcacggaa aacctgagtg aagaacacct
    14221 gcacgccgcg ttccgccagc aatttcatgt tagtgccgtt tttctccagc gccgcaacat
    14281 cagacaccgg aatgccgtaa atgcgctcca tcaccatcat cccttcacta caatagtcag
    14341 ggtaaacttc cgggatgtag agcatcgggc tgtcttcaaa attgcgccga agctgaatgg
    14401 cattggcaga ttcccgcagc aaattcagtt catcaatcaa ggtcttttcg tactcgcgca
    14461 ccacttcggt tgggcgcaga cggcgaccat ccggcagcaa acgcggcacc cagcgagcca
    14521 gacggtagat aagtttcaga tccgctttaa tgaccggcaa aatatccggg cggatgactt
    14581 taatcaccac ctctttacca ttcgatttca atcgcgcggt atgaacctgg gcgatagaag
    14641 cagaagccag cggcttgatt tcaaaatcgt caaaccacgc ttctaccggc aagccgccca
    14701 ttgcagcttc aatctgctgc ttcgccagct tgccatcaaa cggagcaact ttgtcctgca
    14761 ataacgccag ctgatcggca atatgcggtg gaaaaagatc gcggcgggtt gataacattt
    14821 gcccgaactt gatccaaacc ggccccagtt cttgcagggc cagtcgtagt cgctcaccta
    14881 aaagtttgtc tttatgccga tttggcatcc agaataatga gtatcgccat agccgtagcg
    14941 gcagggtgat acgcattttg gggatcagtt catcaagtcc gtagcttaaa aaagtgcgaa
    15001 tgatgaaata taggcgccgt acttcacctg gcgtcattta gcctccagtt tttccagccg
    15061 tttggtcagg gcatcaacag cacgctcgac ggcagccgtc tcttccgcaa accaggccac
    15121 ttcaagcgga ccgggtgcca tacgccactc ttcagtaatg gcttccgcca cataacgttg
    15181 ctggcgctta atgccgtgat gcaggaactt tgcgcctccg cgcatggctt tgctgattcc
    15241 ttcagcggcg atatcaccgg tataaggggc cagcagttcc gcagggtcga actctgccag
    15301 atctgccagc gcaacgaagt tttgcaccac ctgaatatcg ccctgcactt ccagctcacc
    15361 actgcgaatc agtgcggtaa gctgctggcg atcgcgaagt ttcggcaaca cactggcgta
    15421 ggcgataacg gtgcagtcag catcgcctgc ccattcgccc agtacatcaa cctggcgttc
    15481 gctgaacacc agaatcaatg acgtcgaaaa gccttttacc tccacgcgca atactttacc
    15541 cagcagacgc gagcgggccg ttttcagcgc gggtgagcga tacaggaagg tgttgagcag
    15601 actttcaatt cctgccgtca ctaaaggttt aaaaggcatt tccggtctcc tgtcagaact
    15661 tataaccacg atgcagcgcc acaacccctg ccgtcagatt gtagtagtcg acactttcga
    15721 atccggcatc ctgcatcatg gctttcaggg tatcctgatc gggatgcata cggatggatt
    15781 ctgccagata acggtagctg tcggcgtcgt tcgcgaccag tgagccaata cgcggcagca
    15841 catggaagga gtatgcatca taggctttgc tcagcggctc gataattggc ttcgagaact
    15901 caagcaccag caggcggccg ccgggtttca gcacgcgata cattgaacgc agtgctttat
    15961 ctttgtcggt gacgttacgc agaccaaacg aaatggtgat gcaatcaaag gtgttatccg
    16021 ggaacggcag cgcctcagcg ttcgcctgaa catactcaac gttgccaatc acaccgatat
    16081 tacgcagctt ctcgcggccc attttgagca tggattcatt gatatcagca aggaccactt
    16141 tgccagtttc tccgaccagg cgggagaatt tcgctgtcag gtcgccggtg ccaccagcca
    16201 gatccagcac ggtctgccca cggcgtacgc cgctgcaatc aatcgtgaat cgcttccaca
    16261 aacgatgaat accaaatgac atcaaatcat tcatgacatc gtattttgat gccacggaat
    16321 ggaaaacgtg ggcgaccata tccgcttttt gttccttcgc gacggtctga aaaccaaagt
    16381 gcgtcgtttc ttgtgactta tccaccatct caatgcctgc tcatcaaaaa attgttccag
    16441 aagtgtaaca gattgggcgt cgatgcccta gatttctacc cggcttaact actcccaatg
    16501 ggctagcgcg actgctgatt atattcatca tcgcgttgat aagcttcatc attcggctgc
    16561 tccggaaccg accgaagtcg atactcttca tcctggctca ccgcctgttc agccaaatcc
    16621 ggattaatct cgcgtttaat ttctactcct aaaccgcgaa acgcttctgc ctgcgccagc
    16681 acatttccgc gccctgaaga gagttttttc attgcctggc gatagttatc ctgcgctttg
    16741 tcgagacttt gaccaatcgc tgacatgtca tcgacgaaca aacgcatctt gtcgtacagc
    16801 ttgctggcac gatcggcgat ttgctgggcg ttgcggcttt gatgctcata acgccacagg
    16861 ttggcgatag tgcgcagcgc caccagcagc gtagtcgggc taaccagcat gatattgttt
    16921 ttcaacgctt cggtgatcag ctccggctgg cggtcaagcg ccagtaaaaa agcgggttca
    16981 acgggaataa acatcagcac gtaatccagg gttcgcagcc ccggcagctg ttgataatct
    17041 ttgcgtccca gcaaacggat atggttacgc accgacgcga tatgttcctg tagcgcgctt
    17101 tcgcgggtgt agtcgtcttc ggcgttaaaa tagcgttcat aggcgaccag cgtcattttg
    17161 gcgtcgatca ccacatcttt tccctgcggc aggcgcacga tgacatccgg ctgcatccgc
    17221 gagcgggcgt cattttcgat gctgacctgg gtttcatatt catacccttc acgcagaccg
    17281 gaagcctcca gcacccgcgt caatactacc tcgccccagt tgccctgggt tttattgtcg
    17341 cctttcagcg cgcgcgtcag gttgatcgct tcctgggcca tttgcgcgtt gagttgctgg
    17401 agattgcgaa tttcgtgggt cagggtatgg cgttcttgtg cttctttacc gaagctgtcc
    17461 tgaacctgac ggcggaaacc gtccagttgt tcacgtagcg gcgacaacag gctgttcaga
    17521 ctctgacggt tttgctcatc aacccggcga ttgctgtgct caaaaatacg gttggcgagg
    17581 ttttcaaact gctcactgag gcgctgctcg ctgttaatca tctggcgaat tttatcgtca
    17641 gcatgttgct gtgcggcttc catccgcgtg gttacttcac gcagatcggc ctccagagag
    17701 gtgttaatac tttgcaggct gcgcacttcg ttattgagta actcgcactc tgcacgccag
    17761 tgctcgcttt gggtaatttg ttgttttgcc gcgcttaact ccgcgaccat ctcttcacgt
    17821 tcagctaatt gctcggcttt ttgctgcgca tgttgataac tggcaaacag ccagccaatt
    17881 gccacaccca ccaacgcaat aactgcgtaa accatgattg agaaatccac aacgcctcct
    17941 gacgcaacaa cttacccgca caaaatagaa ttgtgctgta caaacgtcca gttggaaagg
    18001 catttcctgc gaggcgctac gcaaaaatac aaaaggccga acgcgtcggc cttcagacag
    18061 gagaagagaa ttacagcaga cgacgcgccg cttccaccac gattttcacc gcttggcttt
    18121 cagtttgttt catcgtctca gcattcggga tctcttgctg ggtgcggtta acgataacac
    18181 ccgctaccat accggcacgc aggccctgac ttgcacacat ggtcagcagg gttgcagatt
    18241 ccatttcata gttcattacg cccatcgcct gccactcttc catagaacct ttaaagtgac
    18301 gaactacgcg accagagtaa gtatcgtaac gttcctgacc tgggtagaag gtatcagaag
    18361 aagctgtcac gccaacgtga gttgtcgcgc caatggattt cgcagcttca accagcgcag
    18421 tcgtacattc gaaatcagcg acagccggga attccagcgg tgcgaagtgc aggctcgcgc
    18481 catccagacg gacagacgcc gtggtaacca ggacatcacc cacattaata tgcggctgaa
    18541 tagcgcccgt tgtaccgata cgcaggaagg tgcgaatgcc cagctgtgcc agctcttcaa
    18601 cagcaataga ggtagacggg ccgccgatac cggtagagca gacgataaca ggtttaccat
    18661 ccagctctgc acgccaggtg gtgaattcgc ggtgagatgc cagcttaacc ggcttatcca
    18721 tcagcgcggc gatcttttcc acacgatccg ggtcgccagg gacgatggca agcgtagccc
    18781 cttgtaaatc gtttttagtg aggccgagat gaaaaacatc agacttggac atatacaact
    18841 cctctgtgaa tcggtttagt cagaagaagc aaaaagacac tttaccgaag ggtttaacat
    18901 tttttcgtga tactcatcac catgacgcaa atgcgttgca taaatttacc caccaaaagt
    18961 gattcaaatc acataaatca ctcttcattc tgcaggactg cataaaagat gagccgattc
    19021 aggcaatgtg atttgttgca tgctgactat agttaacatt gcgcaacatt tttataaggg
    19081 tacggagaat accatggcaa caacacaaca atctggattt gcacctgctg catcgcctct
    19141 cgcttcgacc atcgttcaga ccccggacga cgcgattgtg gcgggcttca cctctatccc
    19201 ttcacaaggg gataacatgc ctgcttacca tgccagacca aagcaaagcg atggcccact
    19261 gccagtggtc attgtagtgc aggaaatttt tggcgtgcat gaacatatcc gcgacatttg
    19321 tcgccgtctg gcgctggagg ggtatctggc tatcgcacct gaactttact tccgcgaagg
    19381 cgatccgaat gattttgccg atatccccac gttgcttagc ggtctggtag caaaagtgcc
    19441 tgactcgcag gtgctggccg atctcgatca tgtcgccagt tgggcttccc gcaacggcgg
    19501 cgatgttcat cgtttaatga tcaccggatt ctgctggggt ggacgtatca cctggctgta
    19561 tgccgcgcat aatccacagc taaaagccgc agtggcgtgg tacggcaaac tgacgggcga
    19621 caagtcgctg aattcaccga aacaacctgt tgatatcgca accgatctta acgcaccggt
    19681 tctcggctta tatggcggtc tggataacag tattccgcag gagagcgttg aaaccatgcg
    19741 ccaggcgctg cgggctgcta atgcgaaagc agagattatc gtgtacccgg atgccgggca
    19801 tgcattcaat gctgattatc gcccgagcta tcatgccgca tctgcgaaag atggctggca
    19861 gcgtatgctg gaatggttta agcagtatgg tgggaagaag tcgctgtaat gagaaaagac
    19921 cgggtggtat taccacccgg tttggatttt acccccgacg caaattctgc gccgcctgca
    19981 ccatgttcgc cagtgccgcg cgggtttctg gccagccgcg cgttttcagg ccacagtccg
    20041 ggttaaccca caggcgctct gccggaatgc gttttgccgc tttcttcagc agggcttcaa
    20101 tccattccac gctcggtacg tttggcgagt gaatgtcata gacgcctgga ccgatttcat
    20161 tcggataatc aaactcttca aacgactcca gcaactccat gtcggaacgc gaggtttcga
    20221 tggtgatgac gtctgcatcc agcgccgcaa tggaatccat gatgtcgttg aactcgcaat
    20281 aacacatgtg agtgtggatt tgtgtgtcat ctttcgccac ggcggcgttg atacggaagg
    20341 cctctacgcc ccactggaga taggcgtccc agtcgctacg acgcagcggt aaaccttcgc
    20401 gcagcgccgg ttcgtcaatc tggatgatac caatccctgc cgcttccaga tcggccacct
    20461 catcacgcag cgccagcgca atctgtttgg cgatggtttc acggctgaca tcttcacgcg
    20521 ggaacgacca gcagagtatg gtcaccggcc ccgtcagcat ccctttcacc ggtttgtcgg
    20581 tcagcgattg cgcatacttc gcccactcca cggtaatcgg tgccgggcgg ctaacgtcac
    20641 caataacaat cggtggcttc acgcagcggg aaccatagct ctgtacccaa ccgttttgcg
    20701 taaagacaaa cccgtcgagg tgctcgccaa agtattccac catgtcatta cgctcggcct
    20761 cgccatgtac cagcacatcc agtcccaaac gttcctgctc aacaatggcc tgcctgatat
    20821 gttccgcaat gcccgtgcgg tagttgttgg cgtcgagatt accctttttg aaatccagac
    20881 gcagggtacg aatttccgtg gtttgcggga aggaaccaat cgtggtggtc ggccacgctg
    20941 gcagtttaaa acgcgcacgc tgggcttcag cacgcacttc atagacattc gcacgctggc
    21001 tgtcctgtgc ggtgatcgtc gccagacgct tttctaccgc cggattatgt acacgagtag
    21061 agtgacgacg cgcctgaatc gggacgctcc actctgccag agctgccgtg tcaccgctgt
    21121 tcagcgcatc gcgcagcagt gccagttcat ggcatttttg tagggcgaag gcaaaccagc
    21181 ttttcacttc cgcatcaaga cgcgtttcca cgctcaggtc gatggggctg tgcagcagtg
    21241 agcaggaaga tgccacccac aaatcgcgtt tgccgacaat gtccttaatt tgcgcatatt
    21301 tctcggtaag atcggcgcgc cagacgttac gaccattgat cagacccgca gacagcaacc
    21361 agtcagaagg caggcgcttg tgcagttcag caacgtcatc tttaccatgt acaaggtcca
    21421 catgcagccc ctgaacaggc agcgcagtaa tcgtgtcgag gtttggcgtt acgccttcaa
    21481 aataggtggt cagaagcagt ttcacctggc cctggagcgc gtcgtaagcg ggtttgtatg
    21541 cgtccagcca cgcctgcggt agttccagta ccagcgcggg ttcgtcgatc tgtacccact
    21601 caatgccgcg ttttgccagt tctgccagca cttgctgata aaccggcaga atgtcgttca
    21661 gcaggctcag gcggtcaaat tgttcacctt tcactttccc cagccacagc caggtaaccg
    21721 gccccagcag cacaggtttc accttgtggc ccagcgccag cgcctcgtcc acttcgtcca
    21781 gcagctgcgt ccaggtcagt ttgaactgtt ggcctttaac gaactccggc accatgtagt
    21841 gatagttggt gttaaaccat ttggtcattt ccgctgccgc cgcaggttcg ccagtcggcg
    21901 cacgtccacg accaatacgg aacagggtgt cgatatctac cgaaccatct ttgttctgat
    21961 gacgcgccgg aacgttaccc agcagcagac tggtggtcag tacatgatcg taccaggcaa
    22021 aatcgcccac cggcagcagg tcgatacccg cttgcttttg ttgatcccag tgacgagcac
    22081 gcaattcacg ccctaccgcc agcagttctt cacgcgtgga gttccccgcc caataacttt
    22141 cttgcgcttt tttcagctcg cgacgcaggc caacgcgagg gaaaccgagg gtgtgattca
    22201 atattgtcat tttttcttcc tctaattata tgtaaatcct atggattttg aatttaggga
    22261 aggcggcaag tttattcatc cccgggagct tactgaagta agtgaccggg gtggagaaac
    22321 gcagccaacg caccataaat ttaaaagacg aaggatttta gccgtccaga tgtttacaca
    22381 tccataattg gcggttactg tatattcctc aagcgcaaat tattcatgcc gaagtgaagg
    22441 actttcatga tcgaagtaaa acacctgaaa acgctacaag cgttgcggaa ctgcggctcg
    22501 ctcgcagccg ctgcggcgac gttgcatcag acgcaatccg ccctgtctca ccagtttagc
    22561 gatctggaac aacgccttgg cttccggcta tttgtgcgta agagccagcc gctacgcttt
    22621 acaccgcagg gagaaatcct gttgcaactg gcaaaccagg tactgccgca aattagccag
    22681 gccctgcaag cctgcaatga accgcagcag acgcgtctgc gcattgccat tgagtgccat
    22741 agctgtattc agtggctgac acccgcgtta gaaaatttcc ataagaactg gccgcaggta
    22801 gagatggatt ttaaatcggg cgtgacgttt gacccgcagc ccgccttgca acagggagag
    22861 ctggatctgg taatgacgtc cgatattctg ccgcgcagtg gcctgcatta ttcgccgatg
    22921 ttcgactatg aagtgcgtct ggtgttagca cctgaccatc cactggcggc gaaaacgcga
    22981 attacaccgg aagatctcgc cagcgagacg ctattaattt atccggtgca gcgtagtcga
    23041 ctggatgtct ggcggcattt tcttcagccg gcaggcgtca gcccgtcact gaaaagcgtc
    23101 gataacacct tattgttgat tcagatggtt gccgcgcgga tgggtattgc cgcgctaccg
    23161 cattgggtag tagagagttt tgagcgccag ggtctggtgg tgaccaaaac cctgggcgaa
    23221 ggcttgtgga gccgactgta cgccgccgtg cgcgatggcg agcagcgtca gccagttacg
    23281 gaagcgttta ttcgctcagc gcgcaatcac gcctgcgatc atctgccgtt tgtgaagagc
    23341 gcggagcgac ccacttacga tgcacccaca gtgaggccag gatcaccagc gcgcctgtaa
    23401 taaacgttgg ccagtgcggc tgttggtgcc agatagccag gtttaccagc agccctgccg
    23461 gaacgtgcat attattcata atgcccagcg ttccggcgtc cacctgcgtc gcgccgtagt
    23521 tccacataaa gtagccaatc ccggaagcca ccacgccaag aaacaccaga atgccccatt
    23581 gcagcgtggt ttgcggcatt ttctgcgcat ttcccagcaa gaaccatgca atcactgcca
    23641 ccagaaacgc gccaagatag aaccacgcaa aggcgttatg ctgtggcatc gggcgagttt
    23701 ccatcaggcg tttgtaaccc accatgccaa tggcaaaagt gatattggag agttgcacca
    23761 gcagcaagcc agtccagaaa tggtcggtga cctgatcata gcgaataatc ccggcaccaa
    23821 tcaccgccag caaggcgcta aaggcatagc cccagcgcag acggcgctta ctcatgatgt
    23881 cataaatcag cgtgatgtag agcggcgtca gcacggtgaa cagcagcagc tcggaaaccg
    23941 tcaggtagag ataagcgcgg aaactcagca tatacatcac gccaagctgc atcgcgccca
    24001 ccagcatata caggccgacc gttttcaggc tattgccacg ggtacgcaga aacggcagaa
    24061 aaacgagtgc cgccaggcca acacgcacca gcaccgcaaa atagctatcg acgtgccccg
    24121 caaggtactc gccataaaag ctaaaggaga aggcccacag aatcgtggtg atgataagta
    24181 gcgccacaat ggaaaactct ttgattaacg aggatccatt gtagcgaagt atctggttga
    24241 caactgacca aataaagaac gattacgata aatagagttt acgcagataa tgcggcaccg
    24301 cgtcttcggc gttagtacca atcacttcca gctccggatg cagatctttc agccgttgat
    24361 gcgcgctgcc cataatgcag cctttccccg ccatcgacag catttcggca tcgttcatcc
    24421 cgtcaccaaa cgcaatacaa tccttcaggc tgtagcccag tttcttcgcc accgcttcca
    24481 gcgcatggcc ttttgaaacg ccgcccgcca tcacttccag acaggttaag gtagagaaac
    24541 tgacgttgac gcgatcgccc caacgagcgt taatcgcctg ctccagcggc agcagttgtt
    24601 catgggaatc gcaggtgaag aacactttgc tgacgccttc cggctccagt aatccaggct
    24661 catacagcgc atatttgaac accgcttctt taaaaaagcg catctcttcc gggcgatggc
    24721 gattcataaa ccattcgtcg tcgcgataaa cgttagtaat gatgtccgga ttgtcgttga
    24781 ctacgccaaa cagatcgctg gcaatgtcgc gatccaggtt atgagcaaaa atcagattgc
    24841 catccagatc gtgaacgcgc gcgccattgg aggtaatcat gtaagactta atctccagat
    24901 tatcgcgaat ttgccccaca tcaacgtggt gacgaccggt cgcaaacaca aagttgatgc
    24961 cgcgcgcggt gagcagcttc agagtttctt tggcgtaagg ggataacgta tggtcgggag
    25021 aaagtaacgt gccatctaaa tcagacgcaa caacctggta cataagaaat ttaaacctct
    25081 gtagagcggt ttccgctggg tgagttatgc ctgttgaaaa aatcaacgat ggcgtggagc
    25141 gcgactgagc gcattgcgtc cttttcaaaa aggatctcat ggtacgcacc tttaattacc
    25201 aacggccgtc ctccttcgac aggatggccc gcggcggtgc ggagttcaca aaaacggtcg
    25261 tgcatgcggt tatccaccac gcgttcctct tcagcctgca agagaagcgt tggcgtggcg
    25321 tcatcacccg caccggctaa cacctgttcg ccagccagaa tactttcgcg tacccaatgg
    25381 taggtcggcc caccgacgcg aatcgttggg tcatcagcat agaagcgtaa gttacgtcga
    25441 tagcgctgtc tgctgtgggt cagtacgttg atagcaaacg gcaacgcgcg ccagcgcccg
    25501 gtgcctattg catagccatc acggaaacgt ggatgcgctt cggcccagtt gaggatctgc
    25561 cgtgccataa atgacggcat acgaatcacg atcccaaaca ttggcgcagt tagcgcaatg
    25621 gcgtcacata cacctggatg gcgttgcaga aataatgtgg agatcgctcc gcccatcgaa
    25681 tgtgccagta tatagcgttt acgccacgga ccgggctgga cctcctgttg ccaaaatgcc
    25741 gccagatcat caacataatc attaaagcga ttaacatgcc cgagatgcgg atcggctaac
    25801 aggcgaccgg aacgtccctg cccgcgatgg tcgatgatta agacatcaaa ccccaaatgg
    25861 aacaggtcgt aggccagttc cgcatatttt acgtagctct caatacgccc cggacagatg
    25921 actaccaccc ggtcatggtg ctgtgcgcga aaacggacaa agcgcaccgg aatgtcatcc
    25981 acaccagtaa actctgcttc atcacgctga cgccagaaat cagtcagcgg tcccatggta
    26041 aaagcagcaa acgcgttttc tcttgtttcc cagtcttttt gctgctgaaa catcgggtaa
    26101 tctgcctctt aaaccacgta aaatcgtttt tttaagcgtg cctgacacaa cgctgcgaca
    26161 gtagcgtatt gtggcacaaa aatagacaca ccgggagttc atcatgacct tagaatggtg
    26221 gtttgcctac ctgctgacat cgatcatttt aagcctgtcg ccaggctctg gtgcaatcaa
    26281 cactatgacc acctcgctca accacggtta tcgcggcgcg gtggcgtcta ttgctgggct
    26341 tcagaccgga ctggcggttc atattgtgct ggttggcgtg gggttgggga cgctattttc
    26401 ccgctcagtg attgcgtttg aagtgttgaa gtgggcaggc gcggcttact tgatttggct
    26461 gggaatccag cagtggcgcg ccgctggtgc aattgacctt aaatcgctgg cctctactca
    26521 atcgcgtcga catttgttcc agcgcgcagt ttttgtgaat ctcaccaatc ccaaaagtat
    26581 tgtgtttctg gcggcgctat ttccgcaatt catcatgcca cagcagccac aactgatgca
    26641 gtatatcgtg ctcggcgtca ccactattgt agtcgatatt attgtgatga tcggttacgc
    26701 cacccttgct caacggattg ctctatggat taaaggacca aagcagatga aggcgctgaa
    26761 taagattttc ggctcgttgt ttatgctggt gggagcgctg ttagcatcgg cgaggcatgc
    26821 gtgaaaaata atgtcggatg cggcgtaaac gccttatccg acttactctg atgacgcgtc
    26881 tggcatcaac gcgaaataat caaatgaatg ccaaatccgg caaataacgc cccggcaaaa
    26941 ccatcaatcc acttcgccag acgttgataa ccacggcgca tttgcggcag ggcaaacagg
    27001 ctggcaacga cggtaaacca cgccagtgtt tcgacaataa tcaacgcgaa aatgccccag
    27061 cgctcggtag tgccaacgtt atcgccgaca aacaatgaga ataccgaacc aaaatagata
    27121 atcgctttcg gattggcgag attggtcagt aagcctttca ggaaactgcg cccgcttttc
    27181 gccagctcaa cctgtggtgc aggcgcagat acagcctctt ttttcagtgc accgcgtagc
    27241 atctggtaac ccatccagca gagatacagg ccaccgccaa ccataatcag cgtatgcagc
    27301 caggccattt tttcgataat caaatgcagg ccaagcaacg caatccctgc ccaaaccatt
    27361 acaccgcagg taatgcccag cacgcccatc atcgcttctt tacgggaacg actgacagcg
    27421 gtctgagaga caaaaaagaa atcgggaccg gggctcataa gcgccacaat atgcaccatg
    27481 gcgacggtga gaaataacat caacatacat ttgactcgcg ggggaaacgt ttacggagtc
    27541 ttcatcctgg cactttttta tgccgctgac tactcttcgt cgtcgccgtc aacatgcgcg
    27601 cggataagcg ccataaacgg tttaccaaag cgttccagct tgcgcatccc aacgccgtta
    27661 acgctgagca tttcgctggc ggtgatcggc atctgttcag ccatctcaat caaggttgcg
    27721 tcgttaaaca ccacgtacgg cgggacattg ctttcatcgg caatcgattt acgcagtttg
    27781 cgtaatttgg cgaacagttt gcgatcatag ttgccgccga acgatttctg catcgctttc
    27841 ggtttgagcg ccacgatacg cggcacggca agttgcaaag aggattcgcc gcgcagcacc
    27901 gggcgcgcgg cctctgtcag ttgtagggca gaatgctggg caatattttg cgtcaccagg
    27961 ccgaggtgaa tcagctggcg gatcacgctc acccaatgtt catggctttt atcacggccc
    28021 atgccataga ctttcagttt gtcatgacca tagtcgcgga tacgctggtt attagcacca
    28081 cgaatcactt ccaccacata acccatccca aaccgctgat tcacacgacc aatggtggaa
    28141 agggcaatct gagcatcggt tgaaccgtcg tactgtttcg gcggatcgag gcagatatcg
    28201 cagttcccgc acggctcctg acgcccttcg ccaaaatagt tcagcaatac cagacgacgg
    28261 caagtttgcg cttcggcaaa cgcgcccatc gcattgagtt tgtggcgctc gatatcctgc
    28321 aactgcccct gcggcttctc ttccagacaa cggcgcagcc acgccatatc agccggatcg
    28381 taaaacagca tcgcttccgc gggcaggcca tcacgcccgg cgcgtccggt ttcctgataa
    28441 taggattcga tattgcgcgg aatatcaaag tggaccacga agcgaacgtt tggtttattg
    28501 atgcccatgc cgaacgccac cgtcgccacc acaatttgca ggtcatcgcg ctggaatttt
    28561 tcctgcacat cggcgcgaac attattttcc agcccggcat gataggccgc cgcgctaatt
    28621 cccttgcttt gcaggcgcgc agcggtgtct tctactttcg cgcggctgtt gcagtagata
    28681 atgcctgact taccgcgctg ttcctgcacg tagcgcatca actgatcgag cggtttgaac
    28741 ttctccatca gcatgtagcg aatattcgga cggtcaaaac tgctgatttg aatcagcgga
    28801 tcgttcagcc ccagcaggcg cacgatatcc tggcgcgtgg tgtcgtcggc tgtggcggtc
    28861 agcgccataa acggcagcgt cgggaaccgc tggcgcaact gaccgagcgc ggcatattcc
    28921 gggcggaaat cgtggcccca ttgggagata cagtgcgctt catcgacggc taataacacc
    28981 ggattccagt gcgccagatg ctcaagaaag ttatccagca tcaggcgttc cggggcgata
    29041 tacagtaagc gaatttgccc ggtgcggcag cctgtcatca cttcaagttg ctgttcgcgg
    29101 gtttgcgtcg agttaaggca cgccgccgcc acgccgttgg cttgcagttg atccacctga
    29161 tctttcatca acgaaatcag cggtgaaaca accacggtaa ggccgtttag caataaggca
    29221 ggaatttgat agcaaaggga ttttccgcca ccggtgggca tgacgaccag gcaatcgcga
    29281 ccggaaagca cagtgtcgat aatttcttcc tggccggggc gaaactgttg gtagccaaag
    29341 gtttcttgta aaacctgttt agctccggac tccagattca acacttccgc ctgcgccaca
    29401 ttcaccccga ttgcctgaaa taaaaacagg cgctattttc agcgcctgcg cgagaaactg
    29461 caatgctttt agtctctgag agggtaatcc tggatgctgg gttccagatt tgccaaccac
    29521 tcaaccgttc atcaaaacaa atcgtttagc ataaccccca caccgacacg ggtctggttg
    29581 aagttatagt cgatgagcga ttcgccatag ccgctgtaaa cctgagtata aaggcgcaca
    29641 tgtttggtga tcgggtaact taagcctaac tccgcgccgc cgtagccggt gttccagttg
    29701 tactgtcctt tcgcactgag caccgcatca ccgaggtgat agccgatttt aagctggtag
    29761 taacccatat atttggtgat atccgggtta tcgtcagtat tacccaccac ataccacggc
    29821 ttcacttcta ccagccagtt accgttttct gccatcaggc gagtataaag gcggttccag
    29881 ctgcgggagg tcgggtcgga acgcccgtta gagtcgtggt tataccccat ctccacatcg
    29941 cgcagcgtcc aacctgcaaa acggtaatcg gtggcaaaac cgaggaacaa ttgcggttcg
    30001 tagttggttt cacgaaacgg tgaagactct tcgctattgg acagttgcca ccaggatttt
    30061 tgcgtataag acgcacccaa caccgagttc gggcctaaaa tcccacgcca cagcggaaat
    30121 gccaggctca actgaaactt tacttcatcc ttacgcgcat tttccgccca gtcgtaactg
    30181 gcaatcgctt ctttattcag atcgctggtt tgggtgtaaa tgaggtagtt ggtgtcataa
    30241 ggatagagcg tgaacggatt gtcatgctcc tgcagcatat tggcgataat actgccacgc
    30301 accgctggcg cgtcatgcac ctctttcacc gttgcctctt gtgcatatac tgccataggc
    30361 aacataaaca ccggcaacaa ccagccctgc agagtccgca tcggtcgtgt tctccgtaac
    30421 gaattattga taaggtgaat atttttctgc gggctatttt acatacttaa ctccatagcc
    30481 gttagttatc ccttcctaaa gtagaaacca acaacaaaga agcataaaat caacatttca
    30541 ttaaccaatg aagtgtaagg atgatatgtc tgccgtactg accgctgaac aagccctgaa
    30601 attagtgggt gagatgtttg tttatcacat gccatttaac cgcgcattgg ggatggaact
    30661 ggagcgttac gaaaaagagt tcgcacagct ggcctttaaa aatcagccaa tgatggtggg
    30721 caactgggcg caaagcattt tgcacggcgg ggtcattgcg tcggcgctgg atgtcgccgc
    30781 cggtctggtg tgcgtgggaa gtaccttaac ccgccacgaa accatcagtg aagatgaact
    30841 acgccagcgg ctatcgcgga tggggaccat tgatcttcgc gttgattatc tgcgcccagg
    30901 caggggcgag cgttttactg ctactagtag cctgttgcgt gcaggcaata aagtcgccgt
    30961 cgcccgcgtt gaattacaca atgaagaaca gctttatatt gccagtgcca ccgccaccta
    31021 tatggtaggt tgaagacata aaagcaggta aactgctgtt accaattaaa aatgagtatt
    31081 cccgatggat gcaaaacaaa cgcggcaggg cgtattactc gctcttgccg cttattttat
    31141 ttggggtata gcgccagcgt acttcaagtt gatttactac gtgcccgccg atgaaatcct
    31201 gacgcatcgc gtgatctggt cgtttttctt tatggtggtg ctgatgagca tttgccgcca
    31261 gtggtcctat ttaaaaacgc tgattcagac gccacagaaa atttttatgc tggcagtctc
    31321 tgccgtgctg attggtggca actggctact gtttatctgg gcggtgaaca atcaccatat
    31381 gctggaagcg agccttggtt actttattaa cccgctggtg aacattgtgc tggggatgat
    31441 tttcctcggc gagcgattcc gccggatgca atggctggcg gtgattctgg cgatatgtgg
    31501 cgtgttagtc cagctgtgga cttttggttc gctacctatt atcgcgctgg gactggcatt
    31561 tagttttgcc ttctacggtc tggtacgcaa gaagattgcc gttgaagcgc aaaccggcat
    31621 gttaatcgaa accatgtggc tgctgcccgt ggcggcaatt tacctgtttg ctattgccga
    31681 cagctcaacc agccatatgg ggcaaaaccc gatgtcgctg aatttactgc tgatcgccgc
    31741 cggtattgtc actaccgtac cgctgttgtg ttttaccgcc gctgccacgc gcttgcgtct
    31801 ctcaacgtta ggctttttcc agtacattgg cccgacgctg atgttcctgc tggctgtgac
    31861 gttttatggt gaaaaaccgg gtgccgataa gatggtgact ttcgccttta tttgggtggc
    31921 gctggcaatt tttgtgatgg atgcgattta tacgcagcgt agaacgtcca aataaaaaat
    31981 aaatatattc tgaaaaaata tgccgactct tgcatgagag tgggcatatt gccatgctga
    32041 ccggagactc atacaaggat gtaaaattta tgttacgtat atttatccca acatctaacg
    32101 gtaagatttc cagacgtcgt tatatatttt catttatttt aataaatttc atttttgcct
    32161 ttcttattat cttttttaac gatggagaag caggctttct tgttatagtc tctaccatcg
    32221 tactccatta tctcgtcatc aacatgaatt gccagcgact ccgtgatagt ggtttcatct
    32281 atataaaaac ttatgttttt ggtacattag cagtatatat catctctatc atcacaatga
    32341 tagccgaaga ttttgcctgt tcaggcaatg gttcgatgat ttttttgatt tgttattttt
    32401 ccactttcag tatgctaatg cttgcaccta ctgattcatc aaaacaatag ttatggagta
    32461 tttatgagta aggaatatat gaacgatggt tcattaagtg aaaaatggaa ataccgattt
    32521 aatttttatg atcaacatgg ttttcctgga ttctgggggg caacaccaga atataaagca
    32581 gcatttaaag cattaaaagt aagacaacgc ttaactattc aaatgaattt cattgctttc
    32641 ttctgttcct ggatatattt atttgtcctg gggttatgga aaaaagcaat tatagttcta
    32701 ttacttggta ttctatctct atttgttggt gcactaattg gcgttaacat tctgggaatt
    32761 gccgtagcag cctatgttgc tgttaacacg aacaaatggt tctatgagaa agaggtaaaa
    32821 gggttaaata cctggagcct ttgaataaca ggtggcttag ccagactaag ccaccgctct
    32881 cgttttttac aaccagttct tccgcttaaa gtacagatac ggtgccaggc ccgcgaggat
    32941 cataaagata atcgcgcctg ggtagccgaa actccacttc agttctggca taaactcaaa
    33001 gttcatcccg tagctggagg caaccagcgt tggcggcagg aacacgacgg ataccaccga
    33061 gaaaattttg atgatgcggt tctgctcgat gttgataaaa cccattgccg cctgcatcag
    33121 gaagttcacc ttctggaaca gggattcgtt atgcggcagc agggattcga tatctcgcag
    33181 gatttcacgc gcctgctcca gttgcccacc cggtaaacgc gctttacgca ccaggaagtt
    33241 gagcgcacgc tgggtatcca tcagacacag gcgcactttc cagccgatat cttccagttc
    33301 cgccagagtg gagagcgcct cgtcgtactc atcgccctga tgcccttcca taatcacccg
    33361 gctcaactgc tccaggtcgc tatagatatt ttcaatttca tctgccaact gttcgatttt
    33421 ggtttcgaac agatccagca gcagctcgta ggcgttaccg tccaccatcg actggctacg
    33481 ggcacgcata cgatacagac gaaaagcggg cagttcacgc tcacgcagag taaacagacg
    33541 accatcacgg atggtaaatg ccacagtgga gttaccggcg tgatcttccg catcttcaaa
    33601 gaagaagaag gagtgaatat gcaggccgtc gtcgtcttca aagaaacgtg ccgatgcttc
    33661 gatgtcttcc agttccgggc gggttgccag gctctgacca agttcagatt gtacgcgcag
    33721 tcgctcgtcg tcgtccggtt cgacaagatc aatccatact gcatttacaa ggggttgtga
    33781 ctcttcgact tccagccggg tcagtcggtt attttccagt tgaaatgcgc tcagcatgac
    33841 cgggactccc aatgcttaaa atatcggaca gttcggtggg cacacagaaa caaattgggt
    33901 ttcagaccat taaacagcct gactcagcgc gacgggaaaa attgaggtcg ctgacaaccg
    33961 ctaaggctat cagcaaaaag ggatagcctt aggagttgat cctggatgac aggatagtga
    34021 gccagtatct actgggtgtg tccaaggcga atgtcctctt agagtgatcg tgcgcgcatg
    34081 ttacgccagc aaaattttgc cgtcaacacg caacagaaca ccacagaaca atagttgaac
    34141 ttcgcgcttt ttggtactcg tcaaggtcgc taacaggata aaaaaatccc acatccagga
    34201 cctataatgg cgcatcggct actcattggt aaaggaatga tcaccttgaa tctcaaacgg
    34261 atttttctcg ccctcacctt acttcccttg tttgctgttg ccgctgatga ttgcgcactc
    34321 tcagatccga cgctgaccgt acaggcgtat accgttaatc ctcaaacaga gcgggtgaaa
    34381 atgtactggc aaaaagccaa tggcgaagcg tggggaacgt tacatgctct gctggcggat
    34441 atgaatagtc agggtcaggt gcagatggcg atgaacggcg gcatctatga tgaaagctat
    34501 gcgccgctcg gtttgtacat cgaaaacggt cagcagaagg tggcgttaaa tctcgcttca
    34561 ggtgaaggga atttctttat ccgtcctggc ggcgtgtttt atgtcgcggg agataaagtc
    34621 ggcatcgttc gtctggatgc cttcaaaacc agtaaagaga ttcagtttgc ggtgcagtca
    34681 gggccaatgt tgatggaaaa cggtgtaatt aatccgcgta ttcatcccaa cgtcgcctca
    34741 agcaaaattc gtaacggtgt tgggattaat aaacatggga acgccgtgtt tttgttgagc
    34801 cagcaggcaa caaattttta tgattttgcc tgttatgcca aagcgaaact gaacgttgag
    34861 cagctgcttt atcttgatgg cacgatttca catatgtata tgaaaggcgg ggcaatcccg
    34921 tggcaacgct atccttttgt caccatgatt tccgtcgagc ggaaaggtta aaacgatagt
    34981 tttgtgtcag atactgaaga tggcgcagat gccggatgcg gcgtaaacgc cctatccggc
    35041 ctacatgacg ttgcaattta ttgaatctga atgatttttt aggccaaata aggtgcgcag
    35101 caccgcatcc ggcaacgtta caccgactcc agccgggcgt aagctgccac cagccatttg
    35161 attccctggc cctggaatgc cacctgcaaa cggctatgtt caccgctgcc ttccatattg
    35221 acgatggtgc cttcaccaaa cttagcgtgg cgtacacgct ggccgagctt gtagccgctg
    35281 tcgttctcga ccatcggcgt acccatccgc tgatggctga ccgggcggct taccgtggcg
    35341 cgcaggcgca cctcttccac acactcttcc ggcagctcgc caataaagcg cgacgggcga
    35401 tggtaaacct ctttgccata cagacggcga gtttccgcgt aggtcagcgt cagtttctgc
    35461 atcgcgcggg ttacgccaac gtaggccaga cggcgttctt cttccagacg cccgccttca
    35521 tccagcgaca tctggcttgg gaacatgccc tcttccatac cgacgataaa cacctgcggg
    35581 aactccagac ctttcgccga gtgcatggtc atcagttgta ccgcatcctg ccaggtatcc
    35641 gcctgccctt cgcctgcttc cagcgccgca tgggatagga acgcctgcag cggcattaaa
    35701 tcttcgtctt cttcgttgta gctgaactgg cgcgttgccg tcaccagttc ctctaagttt
    35761 tcgatacgcg tctgaccttt ttcgcccttc tcctgctcgt acatggtacg caggccggag
    35821 tctttaatta cccggtcagt ctgtacatgc agcggcatat cggcagtttc ctgcgctaag
    35881 gcgtcgatca gttccataaa ccgctgtaag gcgctggcag cacgtccggc gagggctttt
    35941 tcctgcaaca gttcacgaca tgcctgccag agtgttaact ggcgatcgcg cgatgtctga
    36001 cgtaccacgt ccagcgtccg gtcaccaata ccccgcgttg gcgtattcac cacacgctca
    36061 aaggccgcgt cgtcattacg gttggcaatc aggcgcagat acgagagcgc atctttgatt
    36121 tcctggcgtt cgaagaagcg catcccgccg taaatacggt acggcatact cgcctgcaac
    36181 agtgcttctt ccagcacacg cgactgggcg ttactgcggt agagaatggc gcactcggca
    36241 agcgccccgc cgttgtcctg ccaggttttg atgcggttaa ccacaaaacg cgcttcatcg
    36301 agttcgttaa aagcgcaata gagggaaata ggctcaccgt ccgcgccatc ggtccacagt
    36361 tttttaccca gacgcccgtt attgttttca atcagggcgt tagcggcgct cagaatattg
    36421 ctggtagagc ggtagttttg ctccagacga atagtttcgg caccggggaa atcattaagg
    36481 aaacgctgaa tattctccac ctgcgccccg cgccagccgt agattgactg gtcgtcatca
    36541 ccgacgatca tcactttgcc ggtgtcgccc gccagcaggc ggatccacgc gtactgaatg
    36601 ttgttggtat cctggaattc gtccaccagg atattggtaa aacgttcgcg gtagtgttgc
    36661 aggatatgcg gcttgttaag ccacaactcg tgagcgcgca gcagcagctc ggcgaagtcc
    36721 accaggcccg cgcggtcaca cgcttcctga tacgcctgat acaccttctg ccaggtctgc
    36781 tccaccggat taccgtagct ttgaatatga tgcggacgca ggccttcatc tttctggctg
    36841 ttgatgtacc acattgcctg ccgcggcggc cactgcttct cgtcgaggtt catggctttg
    36901 atcagacgct taagcaggcg tagctggtct tcactgtcga ggatctggaa atcctgcggc
    36961 agattggcgt ccatatggtg cgcacgcagc aaacggtgcg ccagcccgtg gaaggtgccg
    37021 acccacatac cgccctggct cgtgcccatc agttgcccga tacgatgacg catctccgcc
    37081 gccgctttgt tggtaaacgt caccgccata atcgagtatg gcgagcagtt ttccacgctc
    37141 atcaaccagg cgatacgatg caccagtacg cgcgtcttac cactgcccgc gcccgccagc
    37201 accagaaggt tgctgcgtgg cgcggccacc gcttcgcgct gtttgtcatt aaggctgtcg
    37261 agcaggtaag aaacgtccat tggcaccgcc gcgtaaaaat aggttgggcg gagaagcgca
    37321 acgccctccg ccaaaaagct gggtatatat acagatttgc tgattatatc agcgaggtca
    37381 gagatgccaa ccgggaaatt tccagatgcg gcagtaaacg gctgtcccag gtttgcatca
    37441 gatcgccatt ttccggtctg atccaacaag cctgcattcc gctgcgaatt gccccaccca
    37501 cgtcagtggt gagatcgtcc ccaacatgta agatctcgcc gatcggcacg ttgagttttt
    37561 ccgcagccaa aaagtacata tcgctgaacg gttttgagcg cccgtgcggg ccagcgcgca
    37621 gcacaaactc aaaataatcc cccaaaccaa acagctccgg ctgggcgtta ccgttggtga
    37681 tcgccaccag cggccatttc ttcgccagct gttttaaggt gtcgtgagtt tgctgcggga
    37741 cgtcgattcg gctgcgccat ttggcaaagt tgatcattgc tgcgtgtgcg cctgcactgg
    37801 cttcttcggc actcagcccg gcgtcgagca tcgcttgttc aatcgaacga aaacgccagc
    37861 gcgtcacgtc gtgataaatc tcgggttccg cttcccgtac cgcctggcgc aggcgttgca
    37921 gatcttcatt ctggaagctg cgcagcgccg gatgataatt ttgcacaaag gtaagcgcct
    37981 ctcgctcggt gcgcaaaatc accggacggt tatcgtaaag ggtatcatcc aggtcaaagg
    38041 tgagcgccga gatgcgcccc aaaggccggt aaaaacgcat tatttccccc gtttggcgcg
    38101 tggatgcgcc gcatcgtaca ccgaggcaag gtgttgaaaa tcaagatgag tatagatttg
    38161 cgtggtggag aggttggcat gacccagcag ctcctgcaca ccacgaagat cgccgctcga
    38221 ctccagcata tgcgtggcga acgagtgacg taatttatgc ggatgaacgt gattattcag
    38281 cccttgtttt atgccccatt cggcaaagcg tttctgcaca ttacgcgcgg agatacgctt
    38341 gcccagtttc gacagaaaaa gcgcgtcgtc ttcgctacca aacaggtcgc gcaaatcaag
    38401 ccagtgctca atccacgcca cagcgttgcg accaatcggc aggcggcgct ctttgctgcc
    38461 tttccccata acccacactt caccagactc caggtcgagg tgtttaatat ccagccccac
    38521 cagctcagaa agacgcagac ccgcgccgta catcacttcc agcattgcac ggtcgcgtac
    38581 agcgagggga tcattgatat caatatccag cagccgattc atatcgtcga cgtcgatgtt
    38641 tttcggcaga tgacgcggcg ctttcggtgc cgaaacacct ttcgccgggt tagctttgag
    38701 ttcgttctgg ctgaccagcc agtcaaaaaa gctacgtagc gcagaaagcc gtaacgccag
    38761 acttgctgct cccagccctt tacggcgact gcgtacagca aaattgcgca ccatcgtcac
    38821 atcacattgc tgccagcttt gcaggccgtt ttcgctggca aaattgatga tcgcctcaag
    38881 ctgacgctgg tagttaagca gggttatcgg gctaagctgg cgctccacgc tcagataacg
    38941 taggtagcgt tctacatcgg tgtgtaaatc ggtcatacgc gttcaatcca acgctccaga
    39001 agctccggca acatcagcgc aatttcatga agtaactgcg ttccttgccc ttgttgatag
    39061 tgactggcat cgcgactggt aaacagcacg acacccaaat cagcatcgct tcccagcatc
    39121 gacatcgcca ccgatcccac cgctttcgct tccggtagca ccaccagcag ctctggtccg
    39181 ttaagcggcc caagatagtg ctgttcctgc cccaaacgct gaatacgcag cggttcgaaa
    39241 gactgacggc ttaatgccag atgagtgtgg ttcgacggcg cacctaagcg ccagcgatcc
    39301 ggaaacaggc gcagactcgc acctgccagg ccgagatcgc gcgcccagcg gtgaaagcgc
    39361 atcagcatat cgtcgagact gctggcggcg gtgagactgc gctgcaggta gagtaggcga
    39421 taaaacaggc cttcgttggc gatagcctgt tccatcaaca gcgccatgtt ctcttccaga
    39481 acatgaatat gattacgtgc gcgggccatg tgccactcga ccaacgaaac ggtgccgcgt
    39541 accggatgcg gcacacgtat cgcttctact gcgcgcgcat tacggataaa aaactcagga
    39601 tttttaatca gataatcgac aaccgcccgg tcatcaagct ccgtgagtgt ttcctgcagt
    39661 tcttcccctg gttgcttcat agatgaataa atccgtcgta gacatgtacc gccgggccag
    39721 tcatatataa cgggtgaccc ggacctttcc aggcgatatc aagacgaccg ccggggagtt
    39781 ccacgcgtac ttcttcggcc agcaaacctt gctgaatccc tactgcaacc gccgcacacg
    39841 cgccgctgcc gcaggcctgg gtttctcctg ccccacgctc ataaacgcgt aaacgaatat
    39901 gctcgcgctt aaccacttgc ataaaaccga tattggcgcg ctccggaaaa cgctcgtggc
    39961 tttccagaac aggaccaagc gtttctaccg ccgcggtatc gacatcatcg acctgaatca
    40021 cgcaatgcgg atttcccatc gacaccacgc cgcataagat tgtctgctcg gcggcgcgca
    40081 taatataggt cttttccgct ttgttagcgc gaaacggcac ggcggaaggt tcgaagttgg
    40141 gttcgcccat atttacgcgg accagatcat catcggtgac ggtcagaacc atccgcccgt
    40201 tggcggtgct gacgcggata tcacgcttat tggtcagtcc tttcagacgc acaaaacggg
    40261 caaagcagcg cgcaccgttg ccgcactgcg ccacttcact gccatcagca ttgaaaatgc
    40321 gatagtgaaa atccagttca ggatcatacg gcggctcaac caccagcagt tggtcaaacc
    40381 ctacccccag gtgccgatca gccaggcgac gaatcagctc cggtgaaaaa aagacattct
    40441 gcgttaccgc gtcgacgacc ataaaatcgt tgccaaggcc atgcattttc gagaactgca
    40501 tcatttactc caatcacgcg ggtacagaaa ctgactttta gtaattcacc tgggatggac
    40561 catcgccagt ggcgcgatcg tttttatccg gcaccgtgga ttgcgtttgc gtctctaccg
    40621 gtttggtcgg cggcggtgcg tttttatctg caggcgggaa atagagcgga cctttcagac
    40681 cgcagcccgt caggctgaag agagtaagta atacagtgag tgccttaaac acgtttttca
    40741 ttatggattg cctgtaaagt tcatcgcttt ctgctttcta tcatcgcagg agaagacgta
    40801 aaagcaagcg tttagcgact ctttatgaag tctgaaaagt gaggaaatgc tgcgagtata
    40861 acgcttactc gtggggattt atgttttgct ggtagtttcg tgatcggcac ctcgcgccag
    40921 gatggcttta tgcactatcg caatgtggtt tgtttgttgt cttttttagt tccgtcagcg
    40981 tgaggatgct cgctcggtaa acctgatcat aatgtttacc agaaacaggg aaagacgtgg
    41041 tgtaactgcg ccctaatgaa gagacaaatc tttcgctaca cagagacatc attattccgg
    41101 tgacggatga atcgtgccgg aacgcagccg cagaggtgca aactttgaag ccctgacccc
    41161 atgccgctat actgccgcca tcacttaaaa acaggataca acaatgaacg acagtgaatt
    41221 tcatcgcctg gctgatcaac tctggctgac cattgaagaa cgcctggacg actgggatgg
    41281 cgacagcgat atcgactgcg aaatcaacgg cggcgtactg accattacct ttgagaatgg
    41341 cagcaaaatc attatcaacc gccaggagcc gctgcaccag gtatggctgg caaccaaaca
    41401 gggcggctac cattttgacc tgaaaggcga tgagtggatt tgtgatcgca gcggcgaaac
    41461 cttctgggat ttgctggaac aggcggcgac gcagcaggcg ggtgaaacag tcagtttccg
    41521 ctaagattgc atgccggata agcctcgctt tccggcacgt tcatcacgaa aaatattgct
    41581 gtaatagcgg cgtatcgtga tcctgattgg caggcggcat gttaccgata gattttgtgc
    41641 ggaacggaat cacctgttca cgaccatcaa ccttcacaat ctgatagaac tgcggcaggt
    41701 tgaagttgat gaagcttgag ccgtaggtaa aacggtcatg cgatgacgag tagaagcgac
    41761 tgacgtcacg taccagctcc tctttgctgc cttcgcagtg gtgatatacc tcaacccggt
    41821 tgctttcgtc gagaatgtag atattaaagc cattctcgtc ttgcgtttct tcgaaaaaga
    41881 actggatgat cccttcgctg gcaaagccgt ccaccaccgc cggtaatttg acgtgattgg
    41941 tttcaacctg cactgacagg ccgtgcagtt tgttatgcga aatcgcgcca taaaactcga
    42001 tggcgttttc cagtttctgt accgatacat tcaggcgttc gaagaacaac ccccaggttt
    42061 gaccagaaac gcgcagcgcc ttgaaacgcc cggtttcctg gcgggtgctg gaaagacgca
    42121 attcaataca ctcagaaacc agttgctgca cgcgagtacg aattaagccg cgcagatgct
    42181 ggctataaca gaagacttcc acgctatctg gcggtgcggc gtcctgatgc attttgccga
    42241 gaatagtttt cagggcttcg atcatcgatt gctcgccgtt gaagtgcagc gtacgcactt
    42301 cgttccacga gttgcggtac agcaggtcaa cgctacctac caggcaattt tgattctcgc
    42361 caaagctgaa gacatccagc ttacggaaat cgaaatgcac cacctgattg cggaacgccg
    42421 ctgtcgggtc atattccagg ttaacgataa tcgccagatg gcggatctca cacgggctgt
    42481 agagcgcctt cggtgtcggt gcaggtaagc gcagcgggaa atggtgcgac acgtcggcga
    42541 ccatctcctg caacttaggc aaatcgacaa tgccgttacc tttaatatac aaacgggtgc
    42601 gcgaggtcag caggccgtta aaccatgccc acgccaccag tttattcagg taacggttat
    42661 attccagcgg ctgatggctg atgatcgact caatatttgg cgcgcggtta tacagatacc
    42721 aacctgaacg gttagcccgg cccggcggca cataaataaa ggtcagattc ggttccgaga
    42781 gatcgggtga aatctgcggg tttaccagcg tcactttacc tggtaatgct tcaaacgcgg
    42841 catacagctt acgcgtcagc acgccgatat cctgcggact ggcggagacg ctaaggttat
    42901 tgcgacgcgc aaagcggatc agattacggt agctctgcat catcgcgtcg agcaactcgt
    42961 tgtgcgcctc acgcacctga tcaatcttcc agttagcgcg gttatcgagc attgccagac
    43021 gagcttcgtc ccaaccccac tcgctcacta actggctcaa cactgcgcga cgccagccta
    43081 cgcaggcgcg ttcacggctg agcttttcgc acacttttaa atagaagcag cgacgtacta
    43141 aatccagacg ggtaaaatct tcaatcgccg tcaggtattc agtaacacgc tccagcatca
    43201 tgcagtatgg atcgagacca aacgatacaa tctcgccgtc gtgcaaacgc tgtttgatat
    43261 ctttcgccag cagacgtggg ttcgggtatt cccaggaata ggcttccagc agcagtgttt
    43321 tcagtaccgc tttgtatggg gaatcgatac tcttgtagag ctgccaaagg ctggcaccaa
    43381 agtactcttc agcagaaagc gagcttaagc caccgagatc cagccattca tttggcgtca
    43441 gcacgccctg cgcgtaaagc gtcatcacat agtcgtcgta atgctcttct tcgtcgcacg
    43501 gcaccatatt ccacagaata cgcttaccgg cgagacgcac ggcggtacga taaaattcgt
    43561 caagcagcag tatatgctgg gtggagccac aatcttcgcc ccccaggctg ccgctttcat
    43621 tatgacggaa gcggttttca tcaatcagga agaagctgac ttccacaccc agcgaggcgg
    43681 cccagttttc cagcaggcta catttacgtt gtagcaattg gcgctcttcg ctatcgagcc
    43741 aggattgatg acagacccag atatccaggt cagaggaaca actttgccct acggacgagg
    43801 tgctgcccat ggtgtataca ccagtaattg gaagctcacc tttcggcgga tcctgtactg
    43861 acattccacg atacagttca agctcgttca ggtagtggcg ttgagtttca tcaggcgtgt
    43921 aaaggcaaat gcctttggga acgttaccat caaggtaacc cggcattagc ggatggtgat
    43981 agtgcaacaa tgtcggcagt agactgtaga cctgttggaa tgcaggcccc atagcagcaa
    44041 gcgcgcgatc cacacgcaat tgatttatgg catccagtct ctgtttcaga gtctcaatat
    44101 agaggtacaa gacgtatcgc ctgatttgct acccgtcatg actgtgattc cgccaacatc
    44161 aacggtaaca cgcggcattc gggatatttc gtatgtcaaa ggtaaccgtt accacttttc
    44221 gcgcctggtt tttttagttt cacgacgaaa aaatggtcta aaacgtgatc aatttaacac
    44281 cttgctgatt gaccgtaaag aaagatgcgc tacatacaag tgtagcaccg tttattctct
    44341 gtaaattcct tattacaacg gcgtgaaacg cctgtcagga tccactgcca gacctcattt
    44401 tacggtttgc gcaggcgtct acgtttcacc acaacactga catcactctg gcaaggatgt
    44461 taggatggac cacggatgat aatgacggta acaagcatgt tagacaatgt tttaagaatt
    44521 gccacacgcc aaagcccact tgcactctgg caggcacact atgtcaaaga caagttgatg
    44581 gcgagccatc cgggcctggt cgttgaactg gtaccgatgg tgacgcgcgg cgatgtgatt
    44641 cttgatacgc cgctggcgaa agtaggcgga aaaggcttat ttgtaaaaga gctggaagtc
    44701 gcgctcctcg aaaatcgcgc cgatatcgcc gtacactcaa tgaaagatgt gccggttgaa
    44761 ttcccgcaag gtctgggact ggtcactatt tgtgagcgtg aagatcctcg cgatgccttt
    44821 gtgtccaata actatgacag tctggatgcg ttaccggcag gcagtatcgt cgggacgtcc
    44881 agtttacgtc gccagtgcca actggctgaa cgccgtccgg atctgattat ccgctccctg
    44941 cgcggcaacg tcggcactcg cctgagcaaa ctggataacg gcgaatacga tgccatcatt
    45001 cttgccgtag ccggactaaa acgtttaggt ctggagtcac gtattcgcgc cgcgttgcca
    45061 cccgagattt ctcttccggc ggtaggacaa ggtgcggtgg gtattgaatg ccgccttgat
    45121 gattcacgca ctcgcgagct gcttgccgcg ctgaatcacc acgaaactgc actgcgcgtt
    45181 accgcagaac gcgccatgaa tacccgtctc gaaggcggat gtcaggtgcc aattggtagc
    45241 tacgccgagc ttattgatgg cgaaatctgg ctgcgtgcgc tggtcggcgc gccggacggt
    45301 tcgcagatta ttcgcggtga acgccgcggt gcgccgcaag atgccgaaca aatggggatt
    45361 tcgctggcag aagagctact gaataacggc gcgcgcgaga tcctcgctga agtctataac
    45421 ggagacgccc cggcatgagt atcctggtca cccgcccgtc tcccgctgga gaagagttag
    45481 tgagccgtct gcgcacactg gggcaggtgg cctggcattt tccgctgatt gagttttctc
    45541 cgggtcaaca attaccgcaa cttgctgatc aactggcggc gctgggggag agcgatctgt
    45601 tgtttgccct ctcgcaacac gcggttgctt ttgcccaatc acagctgcat cagcaagatc
    45661 gtaaatggcc ccgactacct gattatttcg ccattggacg caccaccgca ctggcgctac
    45721 ataccgtaag cggacagaag attctctacc cgcaggatcg ggaaatcagc gaagtcttgc
    45781 tacaattacc tgaattacaa aatattgcgg gcaaacgtgc gctgatatta cgtggcaatg
    45841 gcggtcgtga gctaattggg gataccctga cagcgcgcgg tgctgaggtc actttttgtg
    45901 aatgttatca acgatgcgca atccattacg atggtgcaga agaagcgatg cgctggcaat
    45961 cccgcgaggt gacgatggtc gttgttacca gcggtgaaat gttgcagcaa ctctggtcgc
    46021 tgatcccaca atggtatcgt gagcactggt tactacactg tcgactattg gtcgtcagtg
    46081 agcgtttggc gaaactcgcc cgggaactgg gctggcaaga cattaaggtc gccgataacg
    46141 ctgacaacga tgcgctttta cgggcattac aataactctc ataacaggaa gccataatga
    46201 cggaacaaga aaaaacctcc gccgtggttg aagagaccag ggaggccgtg gacaccacgt
    46261 cacaacctgt cgcaacagaa aaaaagagta agaacaatac cgcattgatt ctcagcgcgg
    46321 tggctatcgc tattgctctg gcggcgggcg tcggtttgta tggctggggt aaacaacagg
    46381 ccgtcaatca gaccgccacc agcgatgccc tggctaacca actgacggca ttgcaaaaag
    46441 cccaggagag ccaaaaagcc gagctggaag gcattattaa gcaacaagct gcacaactta
    46501 agcaggcgaa tcgtcagcaa gaaacgctgg caaaacagtt ggatgaagtc caacaaaagg
    46561 tcgccaccat ttccggcagc gatgctaaaa cctggctgct ggctcaggcc gattttctgg
    46621 tgaaactcgc cggacggaag ctgtggagcg atcaggacgt cacgaccgct gcagcgttgc
    46681 tgaaaagtgc agacgccagc ctggcggata tgaatgaccc gagtctgatt accgttcgtc
    46741 gggcaattac cgatgatatc gccagccttt ctgcagtatc gcaggtggat tatgacggca
    46801 tcatccttaa gcttaatcag ctttcaaatc aggtagataa cctgcgtctg gccgataatg
    46861 acagcgatgg ttcgccgatg gattcagacg gtgaagagct ttccagttcc atcagcgaat
    46921 ggcgtatcaa tctgcaaaaa agctggcaga actttatgga caacttcatt acgattcgcc
    46981 gtcgtgatga caccgccgta ccgctgttag cgccaaatca ggatatctat ctgcgcgaaa
    47041 atattcgctc tcgcctgctg gtcgcagcac aagctgtacc gcgtcaccag gaagagactt
    47101 atcgccaggc gctggagaac gtctccacct gggtacgtgc ttactacgat actgatgatg
    47161 ccaccaccaa agcgttcctc gacgaggtgg accagttaag ccagcaaaat atctcgatgg
    47221 atcttccgga aaccctgcaa agccaggcga tgctggaaaa actgatgcag actcgcgtgc
    47281 gtaacctgct ggcacaaccg gcagcaggga caacggaagc taaacctgca cctgcacctg
    47341 cacctgcacc tgcacctgca cctgcacctg cacctgcacc tgcacctgca cctgcaccgc
    47401 aaggtgatac tccggcagcc gcgccgcaag gagaataacc atgctaaaag tgttattact
    47461 ctttgtgttg ctgattgcgg ggatagtggt tggcccgatg attgccggtc atcagggtta
    47521 tgtgctgatc cagaccgaca actacaatat cgaaaccagc gtcacgggcc tggcgatcat
    47581 attgattctg gcgatggtag tgctgtttgc cattgagtgg ctactgcggc ggatcttccg
    47641 cactggcgcg cacacccgtg ggtggtttgt cgggcgtaag cgtcgccgtg cacgtaagca
    47701 gaccgaacag gcgctgctga aactggcgga aggcgattat cagcaagttg aaaagctgat
    47761 ggcgaaaaat gccgatcacg ctgaacaacc ggtggtgaac tatctactgg ctgccgaagc
    47821 cgcgcaacaa cgtggtgatg aagcgcgcgc caaccaacat ctggaacgcg cagcggagct
    47881 ggccggcaat gacaccattc cggtagaaat cacccgtgta cgtctgcaac tggcccgtaa
    47941 tgaaaaccat gctgcacgcc acggcgtgga taagctgctg gaagttacgc cacgccatcc
    48001 ggaagtatta cgtctggcgg aacaggcgta tatccgcaca ggtgcatgga gttctctgct
    48061 ggatatcatc ccatcaatgg cgaaagccca tgttggtgat gaagaacatc gtgcaatgct
    48121 ggaacaacag gcatggattg gcctgatgga tcaggcgcgt gccgataacg gtagtgaagg
    48181 tttgcgtaac tggtggaaaa accaaagccg gaaaacgcgt catcaggtag cgttgcaggt
    48241 ggcaatggcg gaacatctta ttgaatgtga cgatcatgat actgcccagc aaattatcat
    48301 cgatggcctg aaacgccagt acgacgatcg cctactgctg ccgattcctc gactgaaaac
    48361 caacaatccg gaacagctgg aaaaagtgct gcgccagcag atcaaaaacg tcggcgatcg
    48421 cccgctgttg tggagcacac tgggccagtc actgatgaag cacggagaat ggcaggaagc
    48481 atcgctcgcc ttccgcgcag cgctgaaaca acgtccggac gcctacgatt acgcatggct
    48541 tgccgacgcg ctggacagac tgcacaagcc ggaagaagct gcagcgatgc gtcacgacgg
    48601 tttgatgtta acgttgcaga acaacccacc acagtagttc cttctcaccc gggggcaagc
    48661 acctccgggg ccttcctgac acataaaaaa acgcctgctc ttattacgga gcaggcgtta
    48721 aaacaggtct gtatgacaac aagtgggtgc ttcactcaac gttgtgtcca tggtgtctga
    48781 tgaggcataa gcgacatctg tcagtggacg ataagcaccg taaacggctc tgcgtcattc
    48841 cggagtttat gaggcactaa ggcgaacata agagatggaa tgagcatcta ctcgtttatt
    48901 atgccacaga gaatcgggaa ataacatccc ttaacacttg ttatgagata attctgtaat
    48961 cctctttgct tcctgagtaa taacttcctg agtgaatatt taacctgagc ttgatcctac
    49021 acatacttat tatgaatgat aaaattcatt caattaataa cacatatatt aattgccgtt
    49081 aaaactaaaa acagcatcaa taatcaacgc gatataataa acctgcctta catatcaact
    49141 gcgccagagg taggattgaa aacgctctcc tgattttcca attcattttc tggataaata
    49201 aataatttat ttttgtcact attatttatg taatcatcct gtcagggaga gggatctcaa
    49261 ttatcaatgc ttaattacgt catcattttg atgacatgaa accggagcat tttgcatgga
    49321 aatttcgttt tcacccaaac gtcttgttgt tgctgtcgcc gccgctcttc ctctcatggc
    49381 cagcgcagca gataccccgt caactgccac cgcacgcaaa ggctttgccg gatacgatca
    49441 cccaaaccag tatccacaga acgctgcaat ttattgaatt tgcacgatca tgtaggccgg
    49501 ataaggcgtt tacgccgcat ccggcaatca accgcaggcg gccacaaaat ggccgctttt
    49561 ttacttactc accaccagca aatgcgcatg cataatgtca ctggccgggc gaccgtgcgc
    49621 cagcaaatca gccattgctt taagatatgg cggtagatgg cggaaataac gctgataccc
    49681 ggcacacaaa taattcagcc ccggtttgcc gctggcatcg agcatgaagc ggtgtttcgg
    49741 gcagcctccc cagcacgctt ttaacacgtt acaactgcga cactgcgccg gtaattgctt
    49801 aaatttatct tcaccaaacg cctgctgttg cggggaatcg atcatttctg caattgtttg
    49861 ctggtgcata ttccccagcc gatattgtgg ataaacatag tgatcgcagg cgtaaacgtc
    49921 gccgttgtgc tcaacaatca ccgagcgccc acaggttggc tgatgatggc aaaccgcacc
    49981 cggcgcaccg acaaaattgg caaacgccca ttcgatattc atcacgaaaa tcttgccgac
    50041 gtcgcgttta atccagtggt cgaatatcgc caccagaaat tcaccgaact cctcggggcg
    50101 caccgaccat tccgttagct caccctgaat atcaccaggc gcatgcaatt tcagtccttc
    50161 gcgggcagcc gtttcatcag ccaggcgctc gaccaccgga ataaactgga tgaattccac
    50221 tcccgcatcg cacaaaaaat catatacctg caacggttgc tgcgcgctgg tgcgattaac
    50281 gcagaccagc acgttatagt cgacatgatg tttttgcagc agcgtcaggg cacgcatcac
    50341 cagcttatgc gtgggtctgc cacctttagt cacgcgatat tgattgtgga tctcaggcgg
    50401 accatccagc gataaaccaa caagaaaatg atgctccgcg agaaacgcgc accattcgtc
    50461 atccagcagc acgccgttag tctggaagct gttacttatc ttcctgccag caccatattt
    50521 cgcctgtagc gctacggcac ggcggtaaaa ctccagcccg agtagcgttg gttcgccgcc
    50581 ctgccaggta aaagccactt cgttttgcag ttcgctggcg gcgatatagt gacggatata
    50641 cgcttccagc gtgtcatcgt ccatatgcgt gactggcttt tcgcggtaaa gggattgttt
    50701 ttcgagataa aaacagtagt cacagttcag attacaatcg gaaccactcg gtttcgccat
    50761 cacatgaaaa gcacgcgttg gaacctgttg cagcatggtc actccttgcc tgaagtcatc
    50821 cttcaatacg ttaagggcga aatcataccg tggggcaatg agttattacg ggcgtttatt
    50881 gcgaagggag ggtgacgaaa tgcacagaaa acaaaaaacc ccgccgaagc ggggttcaaa
    50941 attggtcggc gagagaggat tcgaacctcc gacccactgg tcccaaacca gttgcgctac
    51001 caagctgcgc tactcgccga aatactgctt tttgaatttt tagttcaatt ctttaaagtc
    51061 gtggtgcgag gggggggact tgaaccccca cgtccgtaag gacactaaca cctgaagcta
    51121 gcgcgtctac caattccgcc accttcgcat tgtcacaact tctaataatg gggtggctaa
    51181 tgggattcga acccacgaca actggaatca caatccaggg ctctaccaac tgagctatag
    51241 ccaccactac aaatcttgtt acgcggtatt actaccaccg cagctcaagc gccgggacta
    51301 aatggcgcgc ccgacaggat tcgaacctga gacctctgcc tccggagggc agcgctctat
    51361 ccagctgagc tacgggcgct tagcgccgtt gcgggggtgg ataatacgga cttcccaccc
    51421 ctctgtctag tcccttttta aataaattgc gcgtttggtt acggtttgtg cgttttgctg
    51481 cttattcctc cagtttatgc gctttcccgt ggcgattaag gccaaaaact ttataaatcg
    51541 ccgtcaccgc cagcataaag atgatgccaa caaacagcga catacgcgta tcttcattaa
    51601 agtacatgcc gatcaaaacg caaatcagga atgccattgt tacgtagttg gcccacggga
    51661 acaggattga gcggaacgga tggctggcaa tcgccgcttt atgtgcacgc cgaaaacgca
    51721 gctggcttat caatatcaca aaccatggca ccatccccgg aagcacgctg gcactgtaga
    51781 cgtagacaaa cacacgctgc ggattgggaa tgatgtagtt caggcatgag ccaattagca
    51841 gaatagcaat agatactgcc acacccgcaa ccggtacgcc gtgacgggaa actttcgcca
    51901 tcgccgccgg taactgacgg tttttcgcca gtgcgtagag catacgtccg caactgtaca
    51961 tgccgctgtt acagccagag agcgcagccg tcagcaccac aaagttgata atgcccgccg
    52021 ctgcggtaat accgattttg gcaaaagtca gtacgaacgg gctgccgttg ctgccaattt
    52081 cattccacgg gaagatggtg acgataacga aaatcgcgcc tacgtagaaa atcaggatcc
    52141 gccacagcac cttgcctacg gcactgcgca gtgtcacctg cggattcttc gcttcaccgg
    52201 cagtaatgcc aatcagctcc acgccctggt aggacgccac cacaatacac agcgcggtca
    52261 ggaacccttt ccagccaccc gcaaagaaac cgccatgctc tgtgagattg ctaaaaccaa
    52321 tcgactgccc accattgcca aagccaaaga aaatcacgcc caggccaatg acaatcatca
    52381 cgataatcgt ggtgactttg atcatcgcga accagaactc gatttcgccg tacaaccgca
    52441 ccgccgccag attcgccaac gccaccagcg ccactgcgat caatgcgggt atccactgcg
    52501 ccatctccgg gaaccagaac tggacataaa cgccaatggc ggtgatttct gagatcccca
    52561 cggccatcca cataaaccag taagaccagg cggtgagata accaaaaaac gggctcatat
    52621 aacgatgcgc ataaacggcg aacgaaccgg taaccggttc gaggaacaac atttcgccca
    52681 ttgaacgcat gatgaaaaag acgaacagcc cggcgatgat ataggccaac aatacggatg
    52741 gcccggccca tttcagggta ctggcggccc ccataaacag gccgacgcca atggtgcccc
    52801 ccagggcgat gagttcgata tgtcgagctt ccagcccacg ctgtagctct ggtttgttat
    52861 ctgccataaa tcctcgtgtt gtgtttgcat gctttccggt gttaccggtt atcgttatgg
    52921 gtacatcgag tgttgcgaat gttttcgtaa ttcaggagaa atggcaaata aagcattaaa
    52981 aatttgaatg ctttgtgtaa taaaaaagca gacaggcgac gaagtgacca ctccgtcgct
    53041 ttacaaagag aggaaaatca gaggttgccg gtgtaatgcc agcgtaaata acgcagcaaa
    53101 cgaagctgac gcttaatgcg gctcggctgc gaaagcaggc ggtagagcca ctccagtccc
    53161 agcgtttgcc agattttcgg tgcgcgtttt acgtgaccgg tgaaaacatc gtaagtcccg
    53221 ccaacgccca tatacagcgc atctggatgc accagacggc agtcgcgcat gaagatctcc
    53281 tgctttggcg atcccatcgc aacggtgacg atttgcgctc cgctggcatg aatgcgttca
    53341 aacagcgcct gacgctgctc gggtttaaaa taaccatcct gactgccaac gatattcaca
    53401 ttccattggt tgcgcagttt agcttcagtt tgcgccagca cttcaggttt accgcccaca
    53461 agaaataccg gcgtcccttc tttgcctgcg cgcgccatca gctcttccca gagatcggca
    53521 ccggcaacgc gggaaacctg cgcctgcggg tactttttac gtactgaacg tacaacgctg
    53581 atgccatccg catatttaaa ttcggcagcg ttaattaact ccctgacctc ggcgttatct
    53641 tcaatggtca gcattttttc ggcattaatg gcaaccagcg ttccctgctt aagctgcccg
    53701 tcagcaaaca gataatcgag ggcatgctgc atatcacgcc aaccaatcaa ctgtaagcca
    53761 cgcagcgtat aggtcggtgc cgtggtgttg ttattcattg ttatccttca acctgcgtcc
    53821 ggagcgatga ttttgtacgt ttatgaatga atccggcgct ttcaaaaagc cagtacaaca
    53881 gttttgcgat catcagacat gcgccgaaga ccacgataaa aaagactacg cgtgagacaa
    53941 acgaatccag cccttcacgt gccagcacga tcatattgaa gatcgcccca aagcagaaac
    54001 tgtgcaatat cgcagcctta tagcgattag tctcgcggtt gcccagctca tacagccagt
    54061 cgaaccattt gatgatcagt ccaaccacaa tcgccccgag tgggatgaac aacgcgccgc
    54121 ccatcaccac cagtgagcct ataagcgtag gcgagatcgc cagtccggag tggttattca
    54181 gcacttccca ggtaaagtag ttggctgagt tcagcaccat actcgggcgc cccggccaca
    54241 gccaggaagg gataaagaca tagaaatcgc ggacaattgg agccaggccc tggaagtcga
    54301 tgttgtcgta gttctgcaac agcaacgcca gattctccca cggcgagaag gtgtcgcgag
    54361 tgagatagag aaacgtatag aacgcttcat cgccgctcac attcattcca tagcgtttta
    54421 acgccagcca gaacatgcca acaatcccca gcacgcccgc cgccgccagc atccacaacg
    54481 aaatccagcc gcgaataatg ccaataaaca ggaagatagc gaatgcgatg atgatattgg
    54541 cgcgagtgcc gccgacaatc atataagtca gcaagccaaa agcgaccgtg ctgacgagga
    54601 aaaacagcca cgctttgctg tcctggcgca gaaagtagac caccagcatc gccgggatga
    54661 aaaagtaaaa gaagcgtttt aacgccacgc cggagacttc actggaaaag atctgactgt
    54721 aggagttaag ccggaacagc aaaaagccgt tgtgcatgaa gaagatgccg acgcttacca
    54781 gcgcgatgcc catcaggatc acccacgtaa gattggtctc cacgcggttc atggtaaaca
    54841 gcggacggcg cggtacatca gcaacgcgtt tgcgtaggcg ggttttgtag gtgacatagt
    54901 aaaccgcgta gaagcagccc gcagaaagca acgcctgcaa caagatttct ggcggcgcga
    54961 caccaacatc aaagcgaaat accagcacgc tggtcagcgg gaagccgaag aaaaaggtga
    55021 gcaaaaacag caatgaaaag aagacattga agttaaagcg cacacggcga aactcaaacc
    55081 aggtcagcgt ggcaataaac agcgtgcaga gcagccagac aacaaacagg ccactgaatt
    55141 gcagcagact catgcgacct ccccggcggc aatcgccaac gcccgctgcc agccttgtag
    55201 atagttaggg ctaaagaagg caatggtgtt tttatccacc gacgccaact ggcgctgcgc
    55261 ttcacgcaca atatcctcgt tgagatcgtc ggtagtaaac agcaccggca aatgttgttc
    55321 cgtcatatcc tgccagaacg gattttcccg gttaagcaca caaggaatgc ccgcctgaat
    55381 cagtaagcac agcgtaccaa tgccctgctg gcgggcaaaa ataaagtaac caagatcgca
    55441 ctgacgaagt agcgccagat aggcgtcaaa ttccagtttt tcgctcagaa tttgtagatt
    55501 ttcttcgctg aataactcca gccccgcctg acgaacttcc tcaatgtacg cttcgttatt
    55561 aggcggatat cccatcggca ccaccacttt taccgtatcg ccaaattgct gatgaacggc
    55621 gcgcaaggca gcaatatgct cattgctgcg gtcgccggag ttccccacca gaatggtcat
    55681 tttcccttca cgttgccgat cgttcgccat cgtattgagc gaagggtcca tccgcgtcgg
    55741 gaagtacagc agttcgcccc gcacctttgg gtgcgttttg gcaaaaaagc tcaaatcgcc
    55801 gcgggtggca aatacacagc cgactcgctt ttgcgccagg cgacgtagtg ggtaaaaaag
    55861 cttatatctc aagccactgg aaagctcata caggtctgcc ccccagatat gccagaaaaa
    55921 ctggctgggc ttaatgccac cactcagcag agccagccac agtgtgggat tgaactgacc
    55981 gtggaagaaa aaacgctgct gacggttagc ttttgctttc gcgatgaccg cttccgccag
    56041 cgattttttc ccagggaaaa attgcacaga aagcgccgga cagctatcac ttaagccgtc
    56101 gtccttgcca acaaccataa actcgcgcgc gtgctcgctc gtcgcggcca gcgcgtcatt
    56161 gaaaaaccgc aaaacggttc ggttatggtg agggatatcc gatcccagta cgtgaatcag
    56221 tacagtcatg cccgcctacg ccagagtaaa aacacgccac aacaaagaga aaaatagacg
    56281 atataagttg ccatatatgc ctgcgccgcg cccagtgcac catgcgcagg gattagccag
    56341 tgggcaaata ccatcaataa agtgaactgg ctgacttccg ccagaatata aaaccgcagt
    56401 gacgctttgg cgatcaccag ataaccaaag acataagcgc ccacttttaa cacatcaccc
    56461 actaactgcc aggcaaagag atcgcgcata gcggtaaatt tattcgacaa cagcagccag
    56521 atagcaaaat cacgcagcag ccagacggta aaactcgccg ccgccactgc cggtaagacg
    56581 aatttcagcg atttaaccac ttcccgggtg atatcgcgct tttccgttag ccgcgacaac
    56641 gtgggcagca aatatacgct gaacgatgcc gtaataaatt gcaggtaggc atcggaaata
    56701 ctgctcaccc cttgccagat ccccacctca tcccagctat actgcgccgc cagcagttta
    56761 cgcatcatga tgtaagcaac aggcaaggtc accgacgtaa tcaacgccat gagcgtaaat
    56821 ttgctcaact gccctgccag accgttatcc cagctgggtt tcagatagct taacgggatg
    56881 acaccacgtt tgatcaacat gatggcggca ggaattacca ccagcgcggg aatcagcgcc
    56941 agacccagca acgccccttc ataaccgccc aaacggtaac tgacgtagta cgcgagaacg
    57001 ccaatcaagc tgccgacaat cagcgataac gcattacctg cggcatcgcg aaagcctttc
    57061 atcagcgcca gtaacaggtt gccccaggcg atccccattt gcaccagcgc cactaaacgc
    57121 accagcccct gatagtcggt attaccaaac aatccctggc tgattggcgc agctgccagc
    57181 acaaaaacca gcgccatcag cgtagagaaa ccaagtacca tcgctgatga agtgccgacc
    57241 acgcggcgca gctgttgcgg attatcatgg tactgggcaa cgtatttggt tacaccgtta
    57301 aagatgccag ccccggcaag cacgccgagc acggtaatca actggcggaa atttgccgcc
    57361 agcccaagcc ccgccggacc aaatgacacc gccagcaact taccgaccag taacccggca
    57421 ccaatcttga ccagtgtact ggccgccgtc cacaaggacg cttttgccaa cgacatatca
    57481 ggaaaagtag ttcaacaaag tcgcaattac cgtacgctga ttgacgggcg acaggttgta
    57541 gaacagcggc aggcgcagca ggcgctcgct ctctttggtg gtgtagcgat cttcaccgtg
    57601 gaactcacca aagtgttccc ccgcagggca accgtgcagc ggaatgtaat gaaacaccgc
    57661 catgatttcc gcttctttca gaaagttaat caacgcgctc cggtcatcaa tatcccgcag
    57721 tttaatgtag aacatatgcg cgttctgcac gcagccatcg ggaatcgacg gcagctcgat
    57781 acgcccggct ttcgccagag gcgctaacgc atcgtagtag ttttgccaca gcgccagacg
    57841 ttgctggttg atacgatccg ctgcttccag ttgcgcccac aggtatgcag cttgcagatc
    57901 ggacatcaaa tagctggagc caatatcgcg ccaggtatat ttatcgacct gaccacggaa
    57961 gaactggctg cggttagtgc ccttttcacg gatgatctcg gctcgttcga ttaacgcttt
    58021 atcgttaatc agcgtcgcgc cgccttcacc gcccgccgtg tagtttttgg tttcatggaa
    58081 gctaaagcag ccaatatgac caatggttcc cagtgcacgc cctttgtaag tggacatcac
    58141 gccctgagcg gcatcttcta ccacaaacaa attatgcttt ttcgccaacg ccataatggt
    58201 gtccatttcg caggccacac ccgcgtaatg gaccggcacg ataacgcgcg ttttgtcggt
    58261 gatcgccgct tcaatcagcg tttcgtcgat gttcatggtg tccgggcgaa catccacaaa
    58321 aacgattttt gcgccacgca gcacaaaggc attggcggtg gagacaaagg tgtagctcgg
    58381 catgatcact tcatcgccag gctggatatc gagcagcagc gccgccatct ccagcgaagc
    58441 ggtgcaggac ggcgtcagta acactttggc gctgccaaaa cgttgctcca gccactgctg
    58501 gcagcgacgg gtaaaaccgc catcgccaca cagtttgccg ctacccattg ccgactgcat
    58561 atagtcgagt tcggttccca ccaccggcgg tgcgttaaat ggaatcatgt gatcacctgt
    58621 ataaccagta cgcggtgctt tctacattcg caccactttg tatgtatcgt ttaagcgcgg
    58681 cggtgttgcc catttgggtc gccacccgca aagttgtttt accgcgagca tacgcccagt
    58741 ttagcgccgt ttgcatcagc tcagcacctg caccgcgtcc agccagcagg ccaattcgcg
    58801 catctgtcgc attgagttcc cgtaaagaga catagccgcg aatatcgccg gacgccgcac
    58861 gtaaaatcag acattgatga tcaaaggtgc cgcgcacggc attttcaatc cactgtgcat
    58921 aaaagcgact gctggcgtca ggcgcatacc acggcgcacg aaaacggctt tgcgcaaatg
    58981 cggcgctggc taactgacgt aatgcgggaa tatcggtctc ttgtgccact acagcaccgc
    59041 tatcactggc attgttcacg ggtagcgcca aatcaacttc accttctacc agggagaatc
    59101 ccagctgttg cagggcatcc agttcacccg tatttgatgc cgcaattttg gcctgcaccc
    59161 gtgaccacgg cgctaacgcg tctggcgtca ggagcggtgc ttcagacgta atgcgcacga
    59221 tggcgctgtt aacaccaaag aaggcgtttt cccaggttag tggctcaata ctggcgcgga
    59281 cgggcacgaa gtaactccag cagatattgg ccgtagccag ttttcgctaa tgaactggca
    59341 gcacgcttca caccctcgtc atcgagccag ccgttacgcc aggcaatctc ttccaggcag
    59401 gcaatcttaa agccctggcg tttttccacc gtctgtacaa aggtgctggc ttcaatcagg
    59461 ctgtcgtgag tgccggtatc cagccaggca aatccgcgcc cgagcagttc aacggtcagg
    59521 ttgcccgcct cgaggtacat ctggttgatg gaggtaatct ccagttcacc acgctccgac
    59581 ggcttcacct gctttgcgta ctccacgact ttactgtcgt agaaataaag cccggtcacc
    59641 gcccagtttg acttcggctg ttttggcttt tcttccagcg agatagcgcg gaaattgtcg
    59701 tcaaactcca ccacgccaaa gcgttccggg tccatcacct gatagccaaa aaccgtcgcc
    59761 ccttcggtgc gcgccgcaac atgacgcagc ttcggactga agccctgacc gaagaagatg
    59821 ttatcgccca gcaccagaca agaaggttca ccattaagga aggtttcacc gatgataaag
    59881 gcctgcgcca gaccgtccgg gctgggctgt tcggcatatt ccagctggat accgaactca
    59941 ctaccatcgc ccagcaggcg ctggaaataa cctttatctt ccggcgtagt gatgatgaga
    60001 atttcgcgga taccggccag catcagcacc gacagcggat agtaaatcat tggcttatcg
    60061 taaatcggca acagttgctt cgatacgccg cgcgtaatcg gatgcaatcg ggtgccggaa
    60121 ccgcccgcca ggataatacc tttcatgttt gcctccgctg aaaattagcc tttcagacct
    60181 aaacgctcgc cctgatagct gccgtcctgc acctgcttcc accagctttc attagccaga
    60241 taccactgca ccgttttacg cattccactt tcaaaggttt cctgcggcag ccagccaagt
    60301 tcacgggcaa ttttcgaagc atcaatggca taacgcagat catgccccgg acggtcagcg
    60361 acaaaggtga tcaagtcact atagtgcacc acgccgtgcg gcttgttcgg agccagttct
    60421 tccagcagct cgcaaatggt ttccacaaca tcgagattct tacgctcgtt gtgaccacca
    60481 atattatagg tttcaccgac tttcccggtg gtcgccacgc aatacagcgc gcgagcgtga
    60541 tcttccacat acagccagtc acggatttgc tgcccgttgc catataccgg cagcgattta
    60601 cccgccagcg cgttgaggat catcagcggg atcagttttt ccggaaagtg gtaaggaccg
    60661 tagttattcg agcagttggt gataagcgtc ggcagaccgt aggtccgcag ccaggcgcgc
    60721 accagatggt cgctgctggc ttttgacgcg gaataagggc tgctcggcgc atacggcgtg
    60781 gtttcggtga agaaatcatc cgtcgagtgc aggtcaccat atacttcgtc agtggagata
    60841 tgatgaaaac ggaacgctga ttttttatct tccgttagcg cattccagta agcccgcgcc
    60901 gcttcaagca atgtataagt cccgacaatg ttggtttcaa taaacgctgc cgggccgtca
    60961 atagaacggt caacatggct ttcggctgcc agatgcatga cacagtctgg ctgatgctca
    61021 gtgaatacgc gtgccagttc tgcccgatcg cagatatcaa ctttctcaaa ggcaaagcgc
    61081 tcgctttgcg cgaccggtgc cagcgacatc aggtttccgg cgtaggtcag cttatcgacc
    61141 actaccaccg cgtcgctcgt ttcgttgatg atataacgca ccagcgccga gccaataaac
    61201 ccggcaccac ctgttatcag aatttttctc atcagcgcca gactcctttg gcatcgacga
    61261 catactgctg atggacattg tcgccattga taactttgaa ctgactatga tcgaccagca
    61321 tcaccagcac gtctgccgtt gccagcgcct cgtcaagctg cgccagagta caaagcccgg
    61381 tcagtttttt cggcaactgg tggatgttag gctcaacaac cagagtttcg ccgctatgcc
    61441 actgggcgat cagttcagcg atttccatcg ccgggctttc gcgcaggtca tcaatattcg
    61501 gtttaaacgc cagaccaaag caggcgattt tcagttcact ggcgcgttta tcggtagccg
    61561 ccaggcaatc agccaccgcc gctttcacct gatcgataac ccagaacggt ttgtgatcgt
    61621 tcacttcgcg cgcggtacgg ataagccgcg cctgctgggg gttctgtgcc acgataaacc
    61681 acggatcaac agcaatgcag tgaccgccca cgccagggcc aggctgaaga atattaacgc
    61741 gagggtgacg attcgccagg cgaatcagtt cccagacgtt aatcccctga tcggcacaaa
    61801 tcagcgacaa ttcattagca aaagcgatat tcacatcgcg gaagctgttt tcggtgagct
    61861 tacacatttc cgccgtccgc gagttagtga cgacacactc accttcgagg aaaattttgt
    61921 acagttcgct ggcgcgggcc gaacaaaccg gcgtcatacc accaatcacg cgatcgtttt
    61981 taatcagctc gaccattacc tgtcctggta acacgcgttc cgggcagtaa gcaatgttga
    62041 cgtccgcctg ctcgcccacc tgctgcggga aagtgagatc tggacgcatc tctgctaacc
    62101 attctgccat cttctcggtt gaccccaccg gcgaggtgga ttcaaggatc accagcgcgc
    62161 cttttttcag cactggcgca atggagcgag cagccgattc aacgtaggtc atatctggct
    62221 catgatcgcc cttaaacggc gtgggtacag caatcagcca ggcatccgct tcaactggcg
    62281 tcgtgctcgc tcgtaaaaaa ccgccttcta cggcagtttt tactacactc gccaaatcag
    62341 gttcgacgat atggatttcg ccacgattga tggtatcaac cgcatgttgg ttgatatcga
    62401 caccaattac ctgtttttgc cgtgaggcaa acgctgctgc cgttggcagc ccgatataac
    62461 ccagtccgat aacagaaatg gtcgcaaaac tcatagtgat atccgattat tttttaacgc
    62521 ttccagaatg cgagagcatg cctgaccatc accatacggg ttatgggcgc ggctcatagc
    62581 ttgatattcg ttttcgtctt ttaaaagacg cgtcacttcc tcgacaattc gctgcttatc
    62641 cgtgcctacc agacgcaccg tacccgccgt caccgcttcc ggacgctcag tggtatcgcg
    62701 catcaccagc acaggtttcc ccagcgaagg cgcttcttcc tgaatgccgc ctgagtcggt
    62761 caaaatcagc caggcgtggt tcatcagcca gacaaacggt aaatactcct ggggatcgat
    62821 cagaatgaca tttttcacat gccccagaat gcgattgacc ggctctctga cgttcgggtt
    62881 gagatgcacc ggatagacaa tctggatgtc ctggtgcgtg gtggcgatgt ctgccagcgc
    62941 gtggcagatt tcttcaaagc cacgaccgaa actttcacgc ctgtgaccgg tcaccagaat
    63001 catcttttta tcggggtcga taaacgggta atttgccgcc agttctgaac gcagcgtgtc
    63061 gctgctcatc acctggtcac gcacccataa cagtgcatca ataactgtat taccagtaat
    63121 gaagattcgg ctatccgcaa cgttttcacg cagcaagttt tgccgggaag tttcggttgg
    63181 agagaagtga tacatcgcca gatgcccggt caatgtacgg ttagcctctt ccggccacgg
    63241 cgaatagaga tcgcccgtgc gcagaccagc ctcaacgtga ccaacaggaa tacgctgata
    63301 aaacgccgcc aggctggttg ccagcgtcgt cgttgtgtcg ccgtgaacca gcacgacgtc
    63361 tggtttgaac tcggcaagaa taggttttag cccttccaga atccgacagg ttatctctgt
    63421 caggccctgt cctggctgca ttatgttgag atcgtagtca ggtacaatgg aaaagagttt
    63481 cagcacctga tcaagcatct cccgatgctg cgcagtgacg caaactttag cctcaaaaaa
    63541 aggatctttt gccaacgcat gcaccaacgg agccatcttg atggcttccg ggcgcgtacc
    63601 aaatacagtc agtactttca catcgattct cttcgaataa gcggtgagcg cctttgcgct
    63661 caccgcagca gtgttgctat ttcgagcaac ggcgggttaa tgcgacacca gccccgatca
    63721 gccccccgac aatgccccac ataatcatca ggaaggcacg acgtgggcta tcgcgtttta
    63781 ccggttcttc cggcgtacgc aaatagcgat aggtctgaaa acgcggatcc agggttggac
    63841 caacattcag ggtgtttaac atggcccgat tctgatcata gtcgagatca aaggccggac
    63901 cgacggcctg taaattttcc agtcgagcct ggagcattgg acgcccaagc aggaacattt
    63961 ctgaatcagg taattcctcg gcaggcacat ctgtcgcact gcgcgaaata ttatgctgct
    64021 cagcaatttt cagcgcctgt tcaatactgt tcatccggcg gtcgtagatg gctttcgcca
    64081 cctcttcctg acgcttcacc tgtgctttca tctggatggt acgcgccgcc catgcgcctt
    64141 tcagctcatc attcagatgg ctggctgcac gctggctggc aaaagcaaca tactgacgta
    64201 acaggttatt agcgtcaggc gcggtttcag caataagctt cacgctgtca ttgaccgcgc
    64261 gggtaaagtc tccggggata aactggatgt tgttaatcat ttcatccagc aacgccgcat
    64321 cggctttgct gttgcccacc atccgctgtt tgtaatagtc ggtttgcagc cagaactctc
    64381 tgcgggtatc ccacgaggcc agttgcataa caaactcttt ataggcttcg tccatgaccg
    64441 atggttggtc ggcagaagcc atgtttgaac ggacatccag gttacgcaaa aattgctgct
    64501 gtgagtaata tccccccagc atattcaccg ttggacgatc ggtaatcgcc gtcgagctcc
    64561 actcctgacg agcaaaaaac gtatacgcca gcgcgattaa cgcaaacgcc agccccatgc
    64621 caataatcca tagcttccca gcccacaagg tacgaaacaa cccacgaata tccagttcat
    64681 tttcagcgtc ttcggccggt ttcccaggca ttggttgtgt catcacatcc tcatttattt
    64741 ggttaaattg gggctgccac cacgatttct acgcagtctg cgttttacgc gcttaataaa
    64801 gcgagcaact ttccaggcac gcttaatgca atatccatag aggaagaatg ctagcaaaaa
    64861 gagcaccagc atgacccact ccgggacaaa atgagaatat tctgccagca agccaatgga
    64921 agcgagcagt gctgcggcaa gggtaatcag cacaaacgcc tgacgggaag taaacccggc
    64981 acgcatgatc aaatggtgaa tatgctgacg gtcaggagag aatgggctca tgcctttacg
    65041 caggcgacgg tacataatcg ccaccatatc cattagcgga atggcgatta tccacaaagc
    65101 ggtaaccggg ctgatgggat gggttttgcc ctgggtcgtt tcgagcagga tccagataac
    65161 ggtaaaacca atcagcgtac tgcccgcatc acccataaag actttgtagc ggcgacccag
    65221 gataccaagg ttaagcatga tgtatggcag gatggcggcg atcatcgcaa agcaccagat
    65281 tgcgaggctg gtttgcccgt cgaaccacaa aatcataccg attgctgcaa acgagacgca
    65341 ggacaacccg cccagcaagc catcaatgcc atcaaccatg ttgaacgcat taatggccgc
    65401 ccagacggca aatagcgtca ggaagtaacc aaacggtccg agcaccatct cccaggagcc
    65461 aaagatataa cccaggctac tgagataaag gttgccgaac accatcataa caatgccaac
    65521 agccgcctgt atggtggcac ggatttttac gctgatatca aaacggtcat ccagcgcgcc
    65581 aatgaaaaca agcacaccgg cacaagcgag atagagagat gcatgcggaa tatagtaatc
    65641 gacaattccg aacgtgaagc aaatccctgc gtaaaccgaa atacccccaa cgagtggtat
    65701 caacccctgg tgacgtttgc ggaagtttgg tttatccact aaaccgactt tttttgccac
    65761 cttacgggca aaaaacagaa acagtgtcgt gaataaaaaa atactgatga gatcagtact
    65821 cactgtcagt aaattcacaa tgcatgttct cagagaaaat tattagcaga agtataacca
    65881 cgaagacctt tattcagaag ggaaagtccg ttccaaaccc accagtcctg tgcaaaaatt
    65941 aaccatttga tatgcaaatt gcataacatg ccagcaaatt ccaggaattt tcctaacatc
    66001 gccagcgcgg cattaagatt acagatataa aagcaaaacg ccacgtaaac acgtggcgtt
    66061 tttggcataa gacaaattta tgagcgtttc atcatttcga agaaatcgtc attggtcttg
    66121 gtcattgcca gtttattaat gaggaattcc attgcatcga tttcgcccat cgggtgaatg
    66181 attttgcgca ggatccacat tttctgcagt tcttcctgag tcgtgagcag ctcttcttta
    66241 cgggtaccag aacggttgta gtcgatagcc gggaagacgc gtttttcagc gatcttacga
    66301 gagaggtgca gttccatgtt gcctgtacct ttaaactctt cgtagataac ttcgtccatt
    66361 ttagaaccgg tatcgataag cgccgtcgcg ataatggtca ggctgccgcc ctcttccacg
    66421 ttacgcgccg caccaaagaa gcgtttcgga cgatgcaggg cgttggcatc cacaccaccg
    66481 gtcaacactt tacctgacgc cggaacaacg gtgttgtaag cgcgcgccag acgagtgatg
    66541 gagtcgagca gaatgataac gtctttcttg tgctcaacca ggcgtttggc cttctcgatc
    66601 accatttccg caacctgaac gtggcgagat gcgggttcgt caaaggtaga agcaacaact
    66661 tcacctttta ccagacgctg catctcggtt acttcttccg gacgttcgtc gatcagcaga
    66721 accatcagca cacaatccgg gtggttgtaa gcaatgctct gagcaatgtt ctgcagcagc
    66781 atggttttac cggctttcgg cggtgccaca atcagaccac gctgaccacg accgataggt
    66841 gatgccagat ccagtacgcg agcagttaaa tcttcagtag aaccgttacc acgttccata
    66901 cgcagacgag agtttgcgtg cagcggggtt aagttctcaa agaggatttt gttgcgggcg
    66961 ttttcaggtt tgtcgaagtt aacttcgtta actttcagca gcgcaaaata gcgttcacct
    67021 tctttcggcg ggcgaatctt accagagatg gtatcaccag tgcggaggtt gaaacggcgg
    67081 atttggctag gggaaacgta gatgtcatca ggaccggcga ggtaggagct gtctgcggaa
    67141 cggaggaaac caaatccatc ctgcaatatc tccagtacgc catcaccaaa gatatcttcg
    67201 ccactctttg cgtgctgctt caggatggca aaaataatgt cctgcttacg catacgagcc
    67261 aggttttcca gccccatatt ttcgccgaga gtgatcagct cagaaaccgg cgtattcttt
    67321 aattcggtaa gattcatagt ggtgtgagtt cttaaacttg gggtaaatct cgaacttaat
    67381 gttgtgaatg gtatggcagg atcatccatg cctgtttacg gtcatcgact catgtctttt
    67441 cgctgcctgg tcacaggaga gtacgcagaa ctgaaacgac aagacggatt gagtgacgag
    67501 ccagaaatct gttcacttcg catttaagat aaaacgggaa gcgttggaaa ttacaagatt
    67561 caaacttaat aaggtatgtt taatacgaag tcaacactaa gttagcatga ctcacgccgg
    67621 gcgtccagtt tttagcgacg gggcacccga acatgaaatt cccttacgcc aggttagcgt
    67681 cgaggaactc tttcaactga cctttagaca gtgcgcccac tttggttgcc gccacttcac
    67741 cgtttttgaa cagcagcaga gtcgggatac cacggatgcc atatttcggc gcagtgccag
    67801 ggttttgatc gatgttcagt tttgcaacgg tcagtttgcc ctgatattcg tcagcgattt
    67861 catccagaat cggggcgatc attttgcacg gaccgcacca ctctgcccag aaatcgacga
    67921 ggatcgcccc gtccgctttg agtacatccg tgtcaaaact gtcgtcagtc aggtgaataa
    67981 ttttatcgct catatataac tccacaggaa taagcctggc gtgttggttt cgttgttggt
    68041 gtaacattaa ccaactaaag gttgacttta tttcaccgga tacgctttcg taaagcaata
    68101 gtaagctgat attctaccac actatgagca aaacacattt aacagaacag aagttttccg
    68161 acttcgccct gcatccgaag gttgtagaag cccttgaaaa aaaagggttt cataactgta
    68221 cgcccattca ggcactggcc cttccgctga cgctggcggg tcgtgacgta gccgggcagg
    68281 cgcaaaccgg taccgggaaa acgatggcgt ttcttacgtc aacgtttcat tatcttctct
    68341 ctcatcccgc gattgccgat cgcaaggtga atcagccgcg tgccttaatt atggcaccga
    68401 cgcgtgaact tgccgtgcag atccatgccg acgcagaacc gctggcggaa gctactggcc
    68461 tgaagctggg tctggcttac ggtggtgatg gctacgacaa acagctgaaa gtgctggaaa
    68521 gcggcgttga cattctgatt ggcaccacgg ggcgtttaat tgactacgcc aagcagaacc
    68581 acattaacct cggtgccatt caggtggtgg tactggacga agccgatcgc atgtacgatc
    68641 tgggctttat taaagatatc cgctggctgt tccgccgtat gccgcctgca aaccagcgcc
    68701 tcaacatgct gttctctgcc acgctttcgt accgggtacg tgaactggcg tttgagcaga
    68761 tgaacaatgc cgaatatatt gaagtggaac cggaacagaa aacgggccac cgtattaaag
    68821 aagagctttt ctacccttct aacgaagaaa aaatgcgttt gctgcaaacg ctgatcgaag
    68881 aagagtggcc agacagagcg attattttcg ccaataccaa acaccgttgt gaagagatct
    68941 ggggccacct ggcggcagat ggtcatcgtg tcggtttgtt gacaggcgat gtcgcgcaga
    69001 aaaaacgtct gcgtattctt gatgaattta cccgtggcga tctggatatt ctggttgcca
    69061 ccgacgttgc cgcgcgtggt ttgcatattc cggcagtgac gcacgtcttt aactacgatt
    69121 tacccgatga ctgtgaagat tacgttcacc gtattggtcg tacaggtcgc gcaggcgcaa
    69181 gcggtcactc tatcagcctg gcgtgtgaag agtatgcatt gaatttgcct gctattgaga
    69241 cctatattgg tcactcaatt ccggtaagca aatacaatcc ggacgcattg atgaccgatc
    69301 tgccaaaacc gctgcgcctc acgcgcccac gtacaggcaa tggtccgcgt cgtactggcg
    69361 ctccgcgtaa tcgtcgtcgt tcaggttaaa taaaatgtca tactcaaaat cattcaaact
    69421 gtatcaagat ggcaagagaa tgaatcccga tgagcatact gtagtaagtg attcaggtga
    69481 aagaatgcag ccaacacaga gacagattga aggatgaaga gtatgggttc cacctcgtcg
    69541 ctgtatgcag ccattgatct cggttcgaat agttttcata tgctggttgt gcgcgaggtg
    69601 gctggaagca tccagacgct gacgcgaata aaacgcaaag tgcgtctggc tgctggcctg
    69661 aatagcgaaa atgccctgtc taatgaagca atggagcgcg gttggcaatg tctgcgcctg
    69721 tttgctgaac gtctgcaaga tatccctccc tcgcaaattc gcgttgtcgc tacggcgaca
    69781 ttacgtcttg ccgtcaatgc gggtgatttt attgccaaag cgcaggaaat cctcggttgt
    69841 ccggtacagg tgatcagcgg tgaagaggaa gcacgtctga tttatcaggg cgttgctcac
    69901 acaactggcg gtgccgatca gcgcctggtg gtggatatag gcggtgccag tactgaactg
    69961 gtaaccggca cgggtgcaca aaccacctcg ttgttcagcc tgtcgatggg ctgcgttacc
    70021 tggctggaac gctattttgc cgatcgtaat ctggggcagg aaaattttga tgctgcagaa
    70081 aaagcggcac gcgaagtgtt acgtccggtt gccgatgaat tacggtatca cggctggaaa
    70141 gtgtgcgttg gtgcttccgg caccgtgcag gcgttacagg aaatcatgat ggcacagggg
    70201 atggatgaac gcattaccct ggaaaagttg cagcaattga aacagcgagc cattcattgc
    70261 ggtcggctgg aggaactgga gattgacggg ctgacgctgg aacgtgcgtt agtgttcccg
    70321 agtggtctgg cgatcctgat tgccattttt accgaactga atattcagtg tatgaccctg
    70381 gcgggcggtg cgctgcgtga aggtctggtc tacggtatgt tgcatcttac cgtcgagcag
    70441 gatattcgca gccgtacgct gcgtaatatt cagcgccgct ttatgatcga tattgatcag
    70501 gcgcagcgcg tagccaaagt tgcggctaac ttcttcgatc aggtggaaaa ggaatggcat
    70561 cttgaagcaa taagccgcga tttgctcatc agcgcctgtc agcttcatga aatcggcctg
    70621 agcgttgact tcaaacaagc gccgcaacac gctgcttatc tggtgcgtaa tctggatctt
    70681 cccggtttta cccccgcaca gaaaaaattg ctggcgacgc tactgctcaa ccagactaat
    70741 ccggtcgatc tctcatcgct gcatcagcaa aatgccgtac cgccgcgcgt cgcagaacaa
    70801 ctctgccgtt tactccgcct ggccatcatt tttgccagcc gtcgccgtga cgatctcgtg
    70861 ccagagatga cattacaggc taaccatgaa ctgttgacct tgacgcttcc gcaaggttgg
    70921 ctaacccaac atccgctggg taaagagatt attgctcagg aaagccagtg gcagagctat
    70981 gtccactggt cgctagaagt gcattaatga gtaagtgccg gatgcgatgc tgacgcatct
    71041 tctccggcct tgattatttc cctcgttttg ccgccatcat cgctttcaga ttcgccagat
    71101 ggctttgccc tttctgcatc cgttcttcgg cgctgaccac tttgcgctcc tgttcccaaa
    71161 tcagatcatc ctgcggcagc tccagcaaaa agcggctcgg ctccgggcgc accagctcgc
    71221 cgtactgacg gcgttcttta cacagcgtaa aggtcaattc cttctgggcg cgggtaatgc
    71281 cgacataggc cagccgccgc tcctcatcga tattatcttc atcgatgctg ctctggtgcg
    71341 gcaaaaaccc ttcttccata ccgaccatgt agacataagg aaactccagc ccttttgacg
    71401 cgtgcagagt catcagttgc acctgatcca gctcttcttc actctcacca cgctccatca
    71461 tgtcgcgcaa agtaaagcgc gtcaccacct gggtgagcgt catcggctca tccagttcgc
    71521 tgccttccag catctccgtc atccagctaa acagttggtt gacgttcttc atgcgcattt
    71581 cggcagcttt cgggctgggc gatgtttcgt acagccagga ttcataatcc atgccgtgga
    71641 tcagatcgcg caccgcggca atcggctccc gctccgccag acgctgaatt tctgccaacc
    71701 agtgagtgaa gcgggtcaat gcttcataac cacgtccgct aagcgtctga ctcaggccca
    71761 tatcaaagct ggcggtaaac atgcttttat tgcgcgtcat cgcccactca cccagctttt
    71821 tcagcgtagc cgggccaatc tctcgcttcg gcgtgttaac gatacgcaga aatgcgctgt
    71881 catcgtccgg gttagtcagc acgcgcagat aagccagcaa gtccttgatt tcaggacgag
    71941 agaaaaacga cgtaccacca gaaattttgt acgggatgcg gttttgcatc aggaattttt
    72001 caaacacccg cgactgatgg ttaccgcgat aaagaatggc gtaatctttg tactgcgttt
    72061 tattgacgaa gtgatgggcg atcagctcgc cagtaacgcg ctcggcttca tgttcctcgt
    72121 tattcgcgct taaaactttt agctctgtgc cgtaacccag ttcggagaac agacgctttt
    72181 caaagacgtg cggattattg gcgatcagga tgttcgccgc tttcaaaata cgtccggaag
    72241 agcggtagtt ctgctcaagc ttaatcacct tcagcgccgg aaaatcctga ctcagcagca
    72301 ccaggttttg tggacgtgca ccgcgccagg agtagatcga ctggtcgtca tcgcccacca
    72361 cggtaaagcg cgcgcggctg cccaccagca gtttcaccag ttcatactgg ctggtgttgg
    72421 tgtcctgata ctcatccacc agcaggtagc gaattttgtt ctgccagcgc tcgcggactt
    72481 cttcattgcg ttgcagcagc aacgtcggca ataaaatcag atcatcgaag tcgagaacgt
    72541 tacaggcttt caggtgtgca tcatacagcc cataacaatg ggcaaaaata cggtcccgct
    72601 cgccaatcgc actggctgcc gcctgggacg gtgttttgag atcgttcttc cagttagaga
    72661 tggtcgaaat caactgttgc aggagaactt tgtcatcttc aatcagccct tcggtcaact
    72721 ctttgagcaa cgccagctga tcggtatcgt caaacagcga aaagttcgcc ttcatcccaa
    72781 gcgccgcata ctcgcgtttg atgatatcca accccagcgt gtgaaaagtg gagatcatca
    72841 gcccgcgcgc ctctttgcga cccagcgtct gcccgacacg ctctttcatc tcgcgcgccg
    72901 ccttattggt aaaggtcacc gccgcgatat gtcgcgcctg ataaccgcaa ccgcggatca
    72961 gatgggcgat tttattggtg atcacacgag ttttaccgga acccgcgccc gccagcacca
    73021 ggcaggggcc ggtaacgaat tcgacagctt gttgttggcc ggggtttaga cgcataggtg
    73081 tattgctcaa tcttcgaacg gggggaggat tgtagcagaa tcgcatttga atgtgaccgc
    73141 gtgtaagccg ctaaccggtt ggctgcggat gtttaaatca gagagagaag accgaaatcg
    73201 gagttcatcg tgaatccatt agacttagaa aatatcgggt cgtaacgttg tgttattact
    73261 ttttcagagt ttactaagga gaggtttact cgtggcgatt aatttcagcc ctaaggttgg
    73321 tgaaatactg gaatgcaact ttggtaacta tcctgttagc caaaatggac cgttcagcac
    73381 gacgtattac gatggccgca ttcctcctga aatgataaaa aacaggttag ttgtcgtgct
    73441 caacggaaaa attaatggca acgcatgcat cgtcgttcca ttatcaacca ctcgcgacca
    73501 gacaagttaa aacgtggaat gcatgttgaa atagccagta atgttatcaa tgacctgcaa
    73561 ttctttgatc agcagattcg ttgggccaaa gccgacctgg tacaacaagt cagtcgaaac
    73621 agattaaaca gagcaaggac ttacagaggg tatcttaatc aatgtttgcc acatgagttg
    73681 gttgcagaca tacagagggc ggtcatcaag tcaatcaatg ccatatcgct cataaattga
    73741 caataaaata accatccccg ataatgactt tgtagcccat agaggcccta agttttctcc
    73801 ccttgaggga cctgcgaagc ccggattttc cgggcttttg ccatatatgt accagccact
    73861 ccctgactga caattacgtt agcatctgcg gatcatgcta aaatcgccgc ctgacaatta
    73921 ttcactcaag gcacgatcat ggcaaaaaca gcagcagcac tgcatatcct tgtaaaagaa
    73981 gagaaacttg ctctggatct tctcgagcag attaagaacg gggccgattt cggcaagctg
    74041 gcgaagaaac actccatttg cccatcaggc aaacgcggcg gtgatttagg tgaattccgc
    74101 cagggtcaga tggttccggc gttcgataaa gtggttttct cttgtccggt actagagccg
    74161 accggcccgc tgcacaccca gttcggatat cacatcatta aggtgctgta ccgcaactaa
    74221 tagcaaggcc ttctccagga gaaggccttg agtgttttct ccctctccct gtgggagagg
    74281 gtcggggtga gggcatcagc gcgcacttaa cccgcaacag caatacgttt catatctgtc
    74341 atatagccgc gcagtttctt acctacctgc tcaatcgcat ggcagcgaat cgcttcgttc
    74401 acatcacgca gttgcgcgtt atctaccgca ccttccggaa tagctttacc cagatcgccc
    74461 ggttgcagct ctgccataaa cggtttcagc agcggcacac aagcgtaaga gaacagatag
    74521 ttaccgtact cggcggtatc agagataacc acgttcattt cgtacagacg cttacgggcg
    74581 atggtgttgg caatcagcgg cagttcgtgc agtgattcat agtaagcaga ttcttcgatg
    74641 atgccggaat caaccatggt ttcgaacgcc agttcaacgc ccgctttcac catcgcgatc
    74701 atcagtacgc ctttatcgaa gtactcctgc tcgccgattt tgccttcata ctgcggcgcg
    74761 gtttcaaacg cggttttgcc ggtctcttca cgccaggtca gcagtttctt atcatcgttg
    74821 gcccagtccg ccatcatacc ggaagagaat tcgccggaga tgatgtcgtc catatgtttc
    74881 tggaacaggg gtgccatgat ctctttcagc tgttcagaaa gcgcataagc acgcagtttc
    74941 gccgggttag agagacggtc catcatcagg gtgatgccgc cctgtttcag tgcttcggtg
    75001 atggtttccc aaccgaactg aatcagtttt tctgcgtatg ctggatcggt accttcttcc
    75061 accagcttgt cgaagcacag cagagagcca gcctgcaaca taccgcacag gatggtttgc
    75121 tcgcccatca ggtcagattt cacttccgca acgaaggacg attccagcac acccgcacgg
    75181 tgaccaccgg ttgcagccgc ccaggctttg gcaatcgcca tgccttcgcc tttcggatcg
    75241 ttttccgggt gaacggcaat cagcgtcggt acgccgaacc cacgtttgta ctcttcacgc
    75301 acttcggtgc ctgggcattt cggcgcaacc atcactacgg tgatatcttt acggatctgc
    75361 tcgcccactt cgacgatgtt gaaaccgtgc gagtagccca gcgccgcgcc gtctttcatc
    75421 agtggctgta cggtgcgcac tacatcagag tgctgcttgt ccggcgtcag gttaatcacc
    75481 agatccgcct gtgggatcag ttcttcgtaa gtacccactt taaaaccatt ttcggtcgct
    75541 ttacgccagg acgcgcgctt ctcggcaatc gcttctttac gcagagcgta ggagatatcg
    75601 agaccagaat cacgcatgtt caggccctgg ttcagaccct gtgcgccaca gccgacgatg
    75661 actacttttt taccctgaag gtagctcgcg ccatcggcga attcatcgcg gcccataaag
    75721 cgacatttgc ccagctgtgc cagctgctgg cgcagattca gtgtattgaa gtagttagcc
    75781 atggtgattc ctcgtgatgt tgtgcttctt attgttcggt tcgcgtttgc gagattgaat
    75841 tcactatatg acaggaaatt tattgcggaa attgatatat tcacaacgtc acattgcaat
    75901 ttttgcaacg tcaacatcga gggctgtccc tgtggattta cgcgatctga aaaccttcct
    75961 gcatctggcg gaaagccgcc attttggccg cagcgcgcgg gcgatgcacg ttagcccatc
    76021 cacgctctca cggcagattc agcgcctgga agaagatctc ggtcagccgc tgtttgtgcg
    76081 cgataaccgc acggtgacgc tgactgaagc gggcgaagag ctgcgcgttt tcgcccagca
    76141 aacgctgttg cagtatcagc agttgcgcca caccatcgat cagcaagggc cgtcgctctc
    76201 tggcgaatta catatcttct gctcggtgac cgctgcctac agccatctgc cgccgattct
    76261 ggatcgcttc cgcgcggaac acccgtcggt ggagattaaa cttactactg gtgatgcggc
    76321 agatgcgatg gaaaaggtgg tcactggtga agcggatctg gcgattgcgg gtaaaccgga
    76381 aaccttgccc ggcgcagtgg cgttttcgat gctggagaat ctggcagtag tgctgattgc
    76441 ccccgcgctg ccctgcccgg tgcgtaatca ggtgtcggta gagaagccgg actggtcaac
    76501 ggtgccgttt attatggccg atcaggggcc ggtacgccgc cgcattgaac tgtggtttcg
    76561 acgcaataaa atcagtaacc cgatgattta cgccacggtt ggcgggcatg aagcgatggt
    76621 atcgatggtg gcactcggct gtggcgtggc attgttgccg gaagtggtgc tggaaaacag
    76681 ccccgaaccg gtgcgtaacc gcgtgatgat tttagagcgc agcgatgaga aaacgccgtt
    76741 tgagctgggc gtgtgtgcgc agaaaaagcg gctacatgag ccgctaattg aggcattctg
    76801 gaagattttg ccgaaccaca aatgacgttg tcgcgcgggt aggcctgata agcgaagcgc
    76861 tatcaggcat ttttccctaa cccgccaaaa agaacctgaa cgccgggtta ttggtttcgt
    76921 cgtggcaatc gtagcccagc tcattcagcc gggtttcgaa atccggttca tggtcgccaa
    76981 gttcgaacgc cgccagtacg cgcccgtagt cggtgccatg gctgcgatag tggaacaaag
    77041 aaatgttcca gtacgtaccc agcgtgttga ggaagcgcag cagcgcgccc ggtgattccg
    77101 ggaattcgaa gctgtagagg cgttcctgca acggatgcga tggacgtccg ccgaccatat
    77161 agcgcacgtg tagcttcgcc atttcgtcgt cggagagatc aaccacgctg tagccgccgt
    77221 cgttgagcat ctgcaaaatt tctttgcgct cttcgaggcc gcggctcagg cgcacaccga
    77281 caaagatgca ggcgtttttg gcatcggcaa aacggtagtt gaactcggtg accgaacgcc
    77341 cgccaagcag ttggcagaat ttgaggaagc tgcctttttc ttccggaatg gtcaccgcca
    77401 acaacgcttc acgctgttcg cccagttcgc agcgttctga gacgtagcgc aggccgtgga
    77461 agttcacgtt ggcaccggaa agaatatgcg ccagccgttc gccgcgaatg ttgtgcaggg
    77521 cgatatattt tttcattccc gccagcgcca gcgcgccaga gggttccgcc accgcgcgca
    77581 catcttcgaa taaatccttc atcgccgcac agatcgcatc gctatcgacg gtgatgatgt
    77641 cgtcgagata ctcctggcat aaacggaagg tttcgtcacc gatgcgtttt accgctacgc
    77701 cttcagcaaa tagccctacg cgcggcagat caaccggatg acccgcatcc agcgctgctt
    77761 tcaggcaggc ggagtcttcc gcttctacgg cgatcacttt gatttgcggc atcagttgtt
    77821 tgatcagcac cgccacgcca gcagccagac cgccgccgcc gactggcaca aatacgcggt
    77881 cgagatgggc gtcctgctgg agcagttcca gcgccagcgt gccttgcccg gcaatcacca
    77941 tcggatggtc gaacggcggc acccaggtga acccctgctg ctgtgacagt tcgatcgctt
    78001 tggctttcgc ttcatcaaag ttcgcgccgt ggagcagcac ttcgccgccg aagccgcgca
    78061 ccgcgtcgac tttgatgtcg gcggtggcgg ttggcataac gatcagggcc ttcacgccta
    78121 accgcgcaga agaaaacgcg acgccctgcg cgtggttacc cgcagaagca gtgatcacgc
    78181 cgtgcgcttt ctgttcttcc gtcaggcccg ccatcatggc gtatgcgccg cgcagcttaa
    78241 agctgtgcac tggctggcga tcttcgcgct tcaccagaat gacgttatca agacgcgacg
    78301 acagtttttc cattttttgt agcggcgtaa cctgcgccgc ctcgtaaacc ggcgcgcgca
    78361 gcactgctct taaatattcg gcaccttccg gagcaccgga caggggttgc gagtcagcca
    78421 ttattaaccc cccagtttcg atttatcgcg caccgcgcct ttgtcggcgc tggttgccag
    78481 gctggcataa gcacgcaggg caaaggagac ctgacgttca cgatttttcg gcgtccaggc
    78541 tttgtcacct cgagcgtcct gcgcttcacg acgcgccgcc agttcggcat cgcttacctg
    78601 taactgaatg ccacggttcg ggatgtcgat agcgatcagg tcaccatctt caatcaggcc
    78661 aatgctgccg ccgcttgccg cttccggtga gacgtggccg atggaaagac cagaggtgcc
    78721 accagagaaa cgaccgtcgg tgatcagcgc acaggctttg ccgagaccca ttgatttcag
    78781 gaagctggtt gggtagagca tttcctgcat ccccggaccg cctttcgggc cttcatagcg
    78841 aattactacc acatctccgg cgacaacttt accgccgaga atcgcttcta ccgcatcgtc
    78901 ctggctttcg tacactttcg ccgggccggt gaatttgagg atgctgtcat cgacgcctgc
    78961 cgttttcacg atgcagccgt tttccgcaaa gttaccgtag agcaccgcca ggccgccgtc
    79021 tttgctgtag gcgtgttcca gcgagcggat acagccattg gcgcgatcgt cgtccagcgt
    79081 atcccaacgg caatcttgcg agaatgcctg tgtggtacga atgcctgcag gacctgcgcg
    79141 gaacatattt tttaccgcgt catcctgggt cagcataacg tcgtattgtt ccagcgtttg
    79201 cggcaacgtc aggccaagta cgtttttcac atcacggttc agtaaccccg cgcgatccag
    79261 ttcgccgaga ataccgataa caccaccagc acggtgaaca tcttccatat ggtatttctg
    79321 ggtgctcggc gcaactttac acagctgtgg aaccttgcgg gaaagcttat cgatatcact
    79381 catggtgaag tcgatttccg cttcctgcgc cgccgccagc aggtgaagta cggtgttagt
    79441 cgatccaccc atcgcgatat ccagcgtcat ggcgttttca aacgccgcct tactggcgat
    79501 attacgcggc agtgcacttt cgtcgttttg ctcgtaataa cgtttggtca attcaacaat
    79561 gcgtttacca gcattaagga acagctgctt acggtcggcg tgggttgcca gcagcgagcc
    79621 gttgcccggc tgcgacaggc ccagcgcttc ggtcaggcag ttcattgagt tagcggtaaa
    79681 catcccggag caggaaccgc aggtcggaca cgcggaacgt tcaacctgat cgctctggga
    79741 gtcagatact ttcgggtctg cgccctggat catcgcatca accagatcga gcttgatgat
    79801 ctgatcggaa agtttggttt tcccggcctc catcgggccg ccggaaacaa agatcaccgg
    79861 aatattcagg cgcagggaag ccatcagcat ccccggggtg attttgtcgc agttagagat
    79921 gcagaccatg gcgtcggcgc agtgggcgtt gaccatatac tcaacggaat cagcgatcag
    79981 ttcgcgagat ggcagtgaat aaagcatccc cccgtggccc atggcaatcc catcatccac
    80041 cgcaatggtg ttgaactctt tggcaacgcc gccagccgct tcaatttgtt cggcgaccag
    80101 tttaccgaga tcgcgcagat ggacgtgacc cggtacaaat tgggtgaacg agttcacaac
    80161 cgcgataatc ggcttgccaa aatcggcatc ggtcattccg gtggcgcgcc acagcgcacg
    80221 agcacccgcc atattacgac catgagtggt ggtggcggaa cggtacttag gcatacttta
    80281 tttactccca gtgtctgtct cgtaaatggg acggtgcgtg ccgtcccatt ttttgtattt
    80341 attgattaac ttgatctaac cagccccatt tatcttcggt ttcgccagtg aagaggccga
    80401 agaaggcttg ctgaatgcgt ttggtaaccg gaccgcaacg gccttcacca acctgaatac
    80461 catctacgct gcgcactggc gtgatttctg ccgcagtacc ggacataaac acttcatccg
    80521 ccaggtacag tgattcgcgc gacagaacct gctcacgcac ttcaattccc agctctttcg
    80581 ccagtttgat gatggcatca cgggtaatac ccggcagcgc ggaggaggtg aacggtgggg
    80641 tgaacagcac gccgtctttc acttcaaaca ggttttcgcc tgcaccttca gagatgtagc
    80701 cattcacatc cagcgcgata ccttcctgat aaccgtggcg gcgcgcttcg ctacccacca
    80761 gcagggaaga gaggtagtta ccaccggctt ttgccgccgt cgggatggtg tttggtgctg
    80821 cgcggttcca ggaggaaacc atcgcatcga tcccctgctc cagcgcttct gcgcccagat
    80881 acgctcccca cgggaaagca gcgataatca cgtcggttga gtatcccgct ggcgggttta
    80941 cgcccatgcc aacatcacca acgaagatca gcggacggat ataggcgctg gtgagattgt
    81001 ttttgcggat cacgtcacga caagcttcca tcagctcatc aatgctctgc gaaaccggga
    81061 agcgatagat tttggcggag tcatgcagac gctgcatatg ctcacgatgg cggaatacaa
    81121 ccggtccttt gtgcgagtcg tagcaacgga tgccttcaaa aaccgaggtg ccatagtgca
    81181 gcgcgtgcga catcacatgc accttcgcgt cttcccagcg aaccatctcc ccattgaacc
    81241 aaatgtaatc agctttcttc gtggtcattt ttatattcct tttgcgctca ggcgcggatt
    81301 tgttgtgatg tggttgtgct ctggcagatg gcaacgtgtg cgacgtccac cagtttattt
    81361 aactgactaa acagtaagtc gaccgaccgt gggctggcaa cggtcaattc gatatttata
    81421 ttttgtgcat cgctggcggc ggccatattc attgagcaga cgtggaaacc acgatgacgc
    81481 accacgcgta aaacacgttc taaggtttct ggattgaagc gagccgatac attgacctga
    81541 tgttgcatca tgataatttc tccaacattt ctgaattact ggcgccaggc ggcaccagcg
    81601 gccagacgtt ctcaagttcg tcgattgaga catgaagcag gtatggccca tcactgttca
    81661 gcatggtgtc gagtgccgct tcaacctggt ctttacgggt gatgtgttgg ccagggatgc
    81721 cgaaggcgct ggctaacatg aggaaatcgg ggttatcagt aagggtggtt tcgctgtatc
    81781 gttcctgaaa aaacagttgc tgccattgtc gaaccatccc taaccgttgg ttatcgagta
    81841 agacgatttt caacggtaac tgcttgcgtt ttacggtgcc cagctcttgc acattcatca
    81901 tgaaagagcc gtcaccggag atacagacaa cggtatcgtt cggtcgcgcg acttgtgcgc
    81961 caactgccgc cggtaaacca aaacccatgg tacctaagcc gctggaggtg atgaaatttt
    82021 ccgggcgagt gtgggcgatg tgctgcgcag cccacatctg gtgctgcccc acatctgtgg
    82081 tcacgacgca atccgcaggt ttacgatccg acagttgttt taacaacaac ggcgcgtaga
    82141 tagcgtcacc gggatggtcg taacgccagg aatgttcatc acgcagctgc gcgcagtgtt
    82201 gctgccagtc attgatattt aacggctgct gtaatgctgg taacagagca tttaaatcac
    82261 cttgtaatgc cacatgtgcc tgacgcagct tgttcatttc tgccgggtcg atatccatat
    82321 ggataacact ggcgtgtggc gcgaaggtgt tcagtttgcc ggtcacccgg tcatcaaaac
    82381 gtgcgcccac ggcgatcagc aggtcacact cctgcaccgc gaagtttgcc gctttggtgc
    82441 cgtgcatccc cagcatgccc agatagtacg gataatctgc ttctactgcg cccagccctt
    82501 tcagcgtaca ggtggcaggc atttttgtgg cagcgagaaa ttcacgcaaa gccggaactg
    82561 cctgcgccat acccacgcca ccgccaacgt acagcatcgg tttttgcgct tttgccagca
    82621 tctggcgcgc ttgctcaact tcggcatgtg ggaaagtcac ttcgttttca acggtggtga
    82681 accacggttc caggtcaccg ctggctaact ggatatcttt tgggatatcg accagaaccg
    82741 gaccaggacg acctgagcag gcaacgtcga atgcttcagc catgatgcgc ggcaactctt
    82801 ccagcgactg caccagaaag ctgtgcttgg tacaggctaa cgacaatccc aggacatcca
    82861 cttcctgaaa tgcgtcagtg ccgataaacg gtgcggacac ttgaccggtg atggcaacaa
    82921 cagggatgga atctaacagt gcgtccgcaa gcccggttat caggttggtt gcgcccggac
    82981 cagacgtggc gatacatacg ccagttttgc cggtagcacg agcataaccg atagccgcca
    83041 ttgccgcacc ctgctcatgt cggcatagca agtgctccac gccgccgtca tacaatgcat
    83101 cgtaaaccgg cataattgcg ccacccggat aaccgaaaac ggtgttcaca ccctgtgccc
    83161 gcaacgcatg taccacccac tgtgcgccat tcatagttag ttccccgtcc tgaatcttga
    83221 gaaacagaat tttgtgctgt tattcattgt ctgctcctcg gttatgtttt taaggtcaaa
    83281 aaaaaccccc ggacctttcg gtgcgggggt cttagttcgt taaggcttga tctctaagcc
    83341 tttcctcgtc caagtgcagc cccgcacggt gggataataa tcaccaccac gctaatcacg
    83401 accaggctaa tcactcgtag aagggctgtc attttgtctt ttcttgcatc ttgttcgaag
    83461 gaatgcctaa agagttacca taggttttgt aaatagtaca agatattttt tggccgattt
    83521 ttatgatgcg tttaataatt tcaatataaa ttgttgtttt ttaaaaataa aatagtg
//
LOCUS       DAPGUL010000009        73706 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.009, whole genome shotgun sequence.
ACCESSION   DAPGUL010000009 DAPGUL010000000
VERSION     DAPGUL010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 73706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73706
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.009"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(65..1309)
                     /gene="mtr"
                     /locus_tag="RHX21_000690"
     CDS             complement(65..1309)
                     /gene="mtr"
                     /locus_tag="RHX21_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan permease"
                     /protein_id="HDV1985923.1"
                     /translation="MATLTTTQTSPSLLGGVVIIGGTIIGAGMFSLPVVMSGAWFFWS
                     MAALIFTWFCMLHSGLMILEANLNYRIGSSFDTITKDLLGKGWNVVNGISIAFVLYIL
                     TYAYISASGSILHHTFAEMSLNVPARAAGFGFALLVAFVVWLSTKAVSRMTAIVLGAK
                     VITFFLTFGSLLGHVQPATLFNVAESNASYAPYLLMTLPFCLASFGYHGNVPSLMKYY
                     GKDPKTIVKCLVYGTLMALALYTIWLLATMGNIPRPEFIGIAEKGGNIDVLVQALSGV
                     LNSRSLDLLLVVFSNFAVASSFLGVTLGLFDYLADLFGFDDSALGRLKTALLTFAPPV
                     VGGLLFPNGFLYAIGYAGLAATIWAAIVPALLARASRKRFGSPKFRVWGGKPMITLIL
                     VFGVGNALVHILSSFNLLPVYQ"
     gene            complement(1463..3352)
                     /gene="deaD"
                     /locus_tag="RHX21_000691"
     CDS             complement(1463..3352)
                     /gene="deaD"
                     /locus_tag="RHX21_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417631.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase DeaD"
                     /protein_id="HDV1985924.1"
                     /translation="MAEFETTFADLGLKAPILEALNDLGYEKPSPIQAECIPHLLNGR
                     DVLGMAQTGSGKTAAFSLPLLQNLDPELKAPQILVLAPTRELAVQVAEAMTDFSKHMR
                     GVNVVALYGGQRYDVQLRALRQGPQIVVGTPGRLLDHLKRGTLDLSKLSGLVLDEADE
                     MLRMGFIEDVETIMAQIPEGHQTALFSATMPEAIRRITRRFMKEPQEVRIQSSVTTRP
                     DISQSYWTVWGMRKNEALVRFLEAEDFDAAIIFVRTKNATLEVAEALERNGYNSAALN
                     GDMNQALREQTLERLKDGRLDILIATDVAARGLDVERISLVVNYDIPMDSESYVHRIG
                     RTGRAGRAGRALLFVENRERRLLRNIERTMKLTIPEVELPNAELLGKRRLEKFAAKVQ
                     QQLESSDLDQYRALLSKIQPTAEGEELDLETLAAALLKMAQGERTLIVPPDAPMRPKR
                     EFRDRDDRGPRDRNDRGPRGDREDRPRRERRDVGDMQLYRIEVGRDDGVEVRHIVGAI
                     ANEGDISSRYIGNIKLFASHSTIELPKGMPGEVLQHFTRTRILNKPMNMQLLGDAQPH
                     TGGERRGGGRGFGGERREGGRNFSGERREGGRGDGRRFSGERREGRAPRRDDSTGRRR
                     FGGDA"
     gene            complement(3345..3425)
                     /gene="yrbN"
                     /locus_tag="RHX21_000692"
     CDS             complement(3345..3425)
                     /gene="yrbN"
                     /locus_tag="RHX21_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YrbN"
                     /protein_id="HDV1985925.1"
                     /translation="MKIADQFHDELCRLAAINFEAHVLHG"
     gene            complement(3532..4416)
                     /gene="nlpI"
                     /locus_tag="RHX21_000693"
     CDS             complement(3532..4416)
                     /gene="nlpI"
                     /locus_tag="RHX21_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020802045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein NlpI"
                     /protein_id="HDV1985926.1"
                     /translation="MKPFLRWCFVATALTLAGCSNTSWRKSEVLAVPLQPTLQQEVIL
                     ARMEQILASRALTDDERAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYL
                     GIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDD
                     PNDPFRSLWLYLAEQKLDEKQAKEVLKQHFEKSDKEQWGWNIVEFYLGNISEQTLMER
                     LKADATDNTSLAEHLSETNFYLGKYYLSLGDLDSATALFKLAVANNVHNFVEHRYALL
                     ELSLLGQDQDDLAESDQQ"
     gene            complement(4525..6660)
                     /gene="pnp"
                     /locus_tag="RHX21_000694"
     CDS             complement(4525..6660)
                     /gene="pnp"
                     /locus_tag="RHX21_000694"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312072.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HDV1985927.1"
                     /translation="MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTV
                     VGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPIRPL
                     FPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQ
                     YVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDQMLGAVVFGHEQQQVVIQN
                     INELVKEAGKPRWDWQPEPVNEALNARVAALAEARLSDAYRITDKQERYAQVDVIKSE
                     TIATLLAEDETLDENELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVL
                     PRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDTFLFHYNFPPYSVGETGM
                     VGSPKRREIGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLAL
                     MDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDGISALQMD
                     IKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKINPDKIK
                     DVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKHAIRRIEEITAEIEVGRV
                     YTGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQ
                     GRIRLSIKEATEQSQPAAAPEAPAAEQGE"
     gene            complement(6907..7176)
                     /gene="rpsO"
                     /locus_tag="RHX21_000695"
     CDS             complement(6907..7176)
                     /gene="rpsO"
                     /locus_tag="RHX21_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HDV1985928.1"
                     /translation="MSLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFA
                     EHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTQLIERLGLRR"
     gene            complement(7325..8269)
                     /gene="truB"
                     /locus_tag="RHX21_000696"
     CDS             complement(7325..8269)
                     /gene="truB"
                     /locus_tag="RHX21_000696"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HDV1985929.1"
                     /translation="MSRPRRRGRDINGVLLLDKPQGMSSNDALQKVKRIYNANRAGHT
                     GALDPLATGMLPICLGEATKFSQYLLDSDKRYRVIARLGQRTDTSDADGQIVEERPVT
                     FSAEQLAAALDTFRGDIEQIPSMYSALKYQGKKLYEYARQGIEVPREARPITVYELLF
                     IRHEGNELELEIHCSKGTYIRTIIDDLGEKLGCGAHVIYLRRLAVSKYPVERMVTLEH
                     LRELVEQAEQQDIPAAELLDPLLMPMDSPASDYPVVNLPLTSSVYFKNGNPVRTSGAP
                     LEGLVRVTEGENGKFIGMGEIDDEGRVAPRRLVVEYPA"
     gene            complement(8269..8670)
                     /gene="rbfA"
                     /locus_tag="RHX21_000697"
     CDS             complement(8269..8670)
                     /gene="rbfA"
                     /locus_tag="RHX21_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001712908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HDV1985930.1"
                     /translation="MAKEFGRPQRVAQEMQKEIALILQREIKDPRLGMMTTVSGVEMS
                     RDLAYAKVYVTFLNDKDEDAVKAGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNS
                     LVEGMRMSNLVTSVVKHDEERRVNPDDSKED"
     gene            complement(8834..11506)
                     /gene="infB"
                     /locus_tag="RHX21_000698"
     CDS             complement(8834..11506)
                     /gene="infB"
                     /locus_tag="RHX21_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HDV1985931.1"
                     /translation="MTDVTIKTLAAERQTSVERLVQQFADAGIRKSADDSVSAQEKQT
                     LIDHLNQKNSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERL
                     AAEEQAQREAEEQARREAEESAKREAQQKAEREAAEQAKREAAEQAKREAAEKDKVSN
                     QQDDMTKNAQAEKARREQEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTDN
                     AEPTEDSSDYHVTTSQHARQAEDESDREVEGGRGRGRNAKAARPKKGNKHAESKADRE
                     EARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIK
                     AMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAP
                     VVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAA
                     FTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPVVVAVNKIDKPEADPD
                     RVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMAS
                     GAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSI
                     PVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMT
                     EGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASN
                     AILVGFNVRADASARKVIEAESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLA
                     EVRDVFKSPKFGAIAGCMVIEGVVKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVR
                     NGMECGIGVKNYNDVRTGDVIEVFEIIEIQRTIA"
     gene            complement(11531..13018)
                     /gene="nusA"
                     /locus_tag="RHX21_000699"
     CDS             complement(11531..13018)
                     /gene="nusA"
                     /locus_tag="RHX21_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005131833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HDV1985932.1"
                     /translation="MNKEILAVVEAVSNEKALPREKIFEALESALATATKKKYEQEID
                     VRVQIDRKSGDFDTFRRWLVVDEVTQPTKEITLEAARYEDESLNLGDYVEDQIESVTF
                     DRITTQTAKQVIVQKVREAERAMVVDQFREHEGEIITGVVKKVNRDNISLDLGNNAEA
                     VILREDMLPRENFRPGDRVRGVLYSVRPEARGAQLFVTRSKPEMLIELFRIEVPEIGE
                     EVIEIKAAARDPGSRAKIAVKTNDKRIDPVGACVGMRGARVQAVSTELGGERIDIVLW
                     DDNPAQFVINAMAPADVASIVVDEDKHTMDIAVEAGNLAQAIGRNGQNVRLASQLSGW
                     ELNVMTVDDLQAKHQAEAHAAIDTFTKYLDIDEDFATVLVEEGFSTLEELAYVPMKEL
                     LEIEGLDEPTVEALRERAKNALATIAQAQEESLGDNKPADDLLNLEGVDRDLAFKLAA
                     RGVCTLEDLAEQGIDDLADIEGLTDEKAGALIMAARNICWFGDEA"
     gene            complement(13046..13498)
                     /gene="rimP"
                     /locus_tag="RHX21_000700"
     CDS             complement(13046..13498)
                     /gene="rimP"
                     /locus_tag="RHX21_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004125659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HDV1985933.1"
                     /translation="MSTLEQKLTEMITAPVEALGFELVGIEFIRGRTSTLRIYIDSED
                     GINVDDCADVSHQVSAVLDVEDPITVAYNLEVSSPGLDRPLFTAEHYARFVGEEVTLV
                     LRMAVQNRRKWQGVIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF"
     gene            complement(13705..13781)
                     /locus_tag="RHX21_000701"
     tRNA            complement(13705..13781)
                     /locus_tag="RHX21_000701"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13745..13747),aa:Met,seq:cat)
     gene            14129..15472
                     /gene="argG"
                     /locus_tag="RHX21_000702"
     CDS             14129..15472
                     /gene="argG"
                     /locus_tag="RHX21_000702"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HDV1985934.1"
                     /translation="MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTAN
                     LGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNT
                     TPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDT
                     DFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVN
                     PIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMMLEANRIGGRHGLGMS
                     DQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQG
                     RWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKG
                     DSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSATSGVPQVENMENKGQ"
     gene            complement(15480..17105)
                     /locus_tag="RHX21_000703"
     CDS             complement(15480..17105)
                     /locus_tag="RHX21_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417641.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HDV1985935.1"
                     /translation="MTVFNKFARSFKSHWLLYLCVIVFGITNLVASSGAHMVQRLLFF
                     VLTILVVKRISSLPLRLLVAAPFVLLTAADMSISLYSWCTFGTTFNDGFAISVLQSDP
                     DEVVKMLGMYIPYLCAFAFLSLLFLAVIIKYDVSLPTKKVTGILLLIVISGSLFSACQ
                     FAYKDAKNKKAFSPYILASRFATYTPFFNLNYFALAAKEHQRLLSIANTVPYFQLSVR
                     DTGIDTYVLIVGESVRVDNMSLYGYTRSTTPQVEAQRKQIKLFNQAISGAPYTALSVP
                     LSLTADSVLSHDIHNYPDNIINMANQAGFQTFWLSSQSAFRQNGTAVTSIAMRAMETV
                     YVRGFDELLLPHLSQALQQNTQQKKLIVLHLNGSHEPACSAYPQSSAVFQPQDDQDAC
                     YDNSIHYTDSLLGQVFELLKDRRASVMYFADHGLERDPTKKNVYFHGGREASQQAYHV
                     PMFIWYSPVLGDGVDRTTENNIFSTAYNNYLINAWMGVTKPEQPQTLEEVIAHYKGDS
                     RVVDANHDVFDYVMLRKEFTEDKQGNPTSEGQG"
     gene            complement(17564..17650)
                     /locus_tag="RHX21_000704"
     tRNA            complement(17564..17650)
                     /locus_tag="RHX21_000704"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17614..17616),aa:Leu,seq:gag)
     gene            complement(17665..17997)
                     /gene="secG"
                     /locus_tag="RHX21_000705"
     CDS             complement(17665..17997)
                     /gene="secG"
                     /locus_tag="RHX21_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HDV1985936.1"
                     /translation="MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFG
                     SSGSGNFMTRMTALLATLFFIISLVLGNINSNKTNKGSEWENLSAPVKTEQTQPAAPA
                     KPTSDIPN"
     gene            complement(18225..19562)
                     /gene="glmM"
                     /locus_tag="RHX21_000706"
     CDS             complement(18225..19562)
                     /gene="glmM"
                     /locus_tag="RHX21_000706"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HDV1985937.1"
                     /translation="MSNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRK
                     IIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMPTPAVAYLTRTFRAEAGIVISAS
                     HNPFYDNGIKFFSIDGTKLPDAVEEAIEAEMEKEISCVDSAELGKASRIVDAAGRYIE
                     FCKATFPNELSLSELKIVVDCANGATYHIAPNVLRELGANVIAIGCEPNGVNINAEVG
                     ATDVRALQARVLAEKADLGIAFDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQL
                     RGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKMQEKGWRIGAENSGHVILLD
                     KTTTGDGIVAGLQVLAAMARNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLEHESVK
                     AVTAEVEAALGNRGRVLLRKSGTEPLIRVMVEGEDEAQVTEFAHRIADAVKAV"
     gene            complement(19555..20403)
                     /gene="folP"
                     /locus_tag="RHX21_000707"
     CDS             complement(19555..20403)
                     /gene="folP"
                     /locus_tag="RHX21_000707"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312083.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HDV1985938.1"
                     /translation="MKLFAQGTSLDLSHPHVMGILNVTPDSFSDGGTHNSLIDAVKHA
                     NLMINAGATIIDVGGESTRPGAAEVSVEEELQRVIPVVEAIAQRFEVWISVDTSKPEV
                     IRESAKVGAHIINDIRSLSEPGALEAAAETGLPVCLMHMQGNPKTMQEAPKYDDVFAE
                     VNRYFIEQIARCEQAGIAKEKLLLDPGFGFGKNLSHNYSLLARLAEFHHFNLPLLVGM
                     SRKSMIGQLLNVGPSERLSGSLACAVIAAMQGAHIIRVHDVKETVEAMRVVEATLSAK
                     ENKRYE"
     gene            complement(20493..22427)
                     /gene="ftsH"
                     /locus_tag="RHX21_000708"
     CDS             complement(20493..22427)
                     /gene="ftsH"
                     /locus_tag="RHX21_000708"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014833437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDV1985939.1"
                     /translation="MAKNLILWLVIAVVLMSVFQSFGPSESNGRKVDYSTFLQEVNND
                     QVREARINGREINVTKKDSNRYTTYIPVQDPKLLDNLLTKNVKVVGEPPEEPSLLASI
                     FISWFPMLLLIGVWIFFMRQMQGGGGKGAMSFGKSKARMLTEDQIKTTFADVAGCDEA
                     KEEVAELVEYLREPSRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISG
                     SDFVEMFVGVGASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLN
                     QMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQVVVGLPDVRGREQILKVH
                     MRRVPLAPDIDAAIIARGTPGFSGADLANLVNEAALFAARGNKRVVSMVEFEKAKDKI
                     MMGAERRSMVMTEAQKESTAYHEAGHAIIGRLVPEHDPVHKVTIIPRGRALGVTFFLP
                     EGDAISASRQKLESQISTLYGGRLAEEIIYGPEHVSTGASNDIKVATNLARNMVTQWG
                     FSEKLGPLLYAEEEGEVFLGRSVAKAKHMSDETARIIDQEVKALIERNYNRARQLLTD
                     NMDILHAMKDALMKYETIDAPQIDDLMARRDVRPPAGWEEPGASNNSGDNGSPKAPRP
                     VDEPRTPNPGNTMSEQLGDK"
     gene            complement(22527..23156)
                     /gene="rlmE"
                     /locus_tag="RHX21_000709"
     CDS             complement(22527..23156)
                     /gene="rlmE"
                     /locus_tag="RHX21_000709"
                     /EC_number="2.1.1.166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uridine(2552)-2'-O)-methyltransferase
                     RlmE"
                     /protein_id="HDV1985940.1"
                     /translation="MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQ
                     SDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRD
                     ELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGS
                     FVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRKP"
     gene            23282..23575
                     /gene="yhbY"
                     /locus_tag="RHX21_000710"
     CDS             23282..23575
                     /gene="yhbY"
                     /locus_tag="RHX21_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014833438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HDV1985941.1"
                     /translation="MNLSTKQKQHLKGLAHPLKPVVLLGSNGLTEGVLAEIEQALEHH
                     ELIKVKIATEDRETKTLIVEAIVRETGACNVQVIGKTLVLYRPTKERKISLPR"
     gene            complement(23731..24207)
                     /gene="greA"
                     /locus_tag="RHX21_000711"
     CDS             complement(23731..24207)
                     /gene="greA"
                     /locus_tag="RHX21_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006178768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HDV1985942.1"
                     /translation="MQAIPMTLRGAEKLREELDFLKSVRRPEIIAAIAEAREHGDLKE
                     NAEYHAAREQQGFCEGRIKDIEAKLSNAQVIDVTKMPNNGRVIFGATVTVLNLDSDEE
                     QTYRIVGDDEADFKQNLISVNSPIARGLIGKEEDDVVVIKTPGGEVEFEVIKVEYL"
     gene            24455..25888
                     /gene="dacB"
                     /locus_tag="RHX21_000712"
     CDS             24455..25888
                     /gene="dacB"
                     /locus_tag="RHX21_000712"
                     /EC_number="3.4.16.4"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001212660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase"
                     /protein_id="HDV1985943.1"
                     /translation="MRFSRFIIGLTSCIAFSVQAANVDEYVTQLPAGANLALMVQKVG
                     ASAPAIDYHSQQMALPASTQKVITALAALIQLGPDFRFTTTLETKGNVENGVLKGDLV
                     ARFGADPTLKRQDIRNMVATLKKSGVNQIDGNVLIDTSIFASHDKAPGWPWNDMTQCF
                     SAPPAAAIVDRNCFSVSLYSAPKPGDMAFIRVASYYPVTMFSQVRTLPRGSAEAQYCE
                     LDVVPGDLNRFTLTGCLPQRSEPLPLAFAVQDGASYAGAILKDELKQAGITWSGTLLR
                     QTQVNEPGTVVASKQSAPLHDLLKIMLKKSDNMIADTVFRMIGHARFNVPGTWRAGSD
                     AVRQILRQQAGVDIGNTIIADGSGLSRHNLIAPATMMQVLQYIAQHDNELNFISMLPL
                     AGYDGSLQYRAGLHQAGVDGKVSAKTGSLQGVYNLAGFITTASGQRMAFVQYLSGYAV
                     EPADQRNRRIPLVRFESRLYKDIYQNN"
     gene            complement(25928..27100)
                     /gene="cgtA"
                     /locus_tag="RHX21_000713"
     CDS             complement(25928..27100)
                     /gene="cgtA"
                     /locus_tag="RHX21_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Obg family GTPase CgtA"
                     /protein_id="HDV1985944.1"
                     /translation="MKFVDEASILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGD
                     VWMEADENLNTLIDYRFEKSFRAERGQNGASRDCTGKRGKDVTIKVPVGTRVIDQGTG
                     ETMGDMTKHGQRLLVAKGGWHGLGNTRFKSSVNRTPRQKTNGTPGDKRELLLELMLLA
                     DVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEKSFVVADIPGLI
                     EGAAEGAGLGIRFLKHLERCRVLLHLIDIDPIDGTDPVENARIIISELEKYSQDLAAK
                     PRWLVFNKIDLLDKAEAEEKAKAIAEALGWEDKYYLISAASGLGVKDLCWDVMTFIIE
                     NPVVQAEEAKQPEKVEFMWDDYHRQQLEEIAEEDDEDWDDDWDEDDEEGVEFIYKR"
     gene            complement(27116..28081)
                     /locus_tag="RHX21_000714"
     CDS             complement(27116..28081)
                     /locus_tag="RHX21_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012135318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDV1985945.1"
                     /translation="MKQQAGIGILLALTTAICWGALPIAMKQVLEVMEPPTIVFYRFL
                     MASIGLGAILAVKKRLPPLRVFRKPRWLILLAVATAGLFGNFILFSSSLQYLSPTASQ
                     VIGQLSPVGMMVASVFILKEKMRSTQVVGALMLLSGLVMFFNTSLVEIFTKLTDYTWG
                     VIFGVGAATVWVSYGVAQKVLLRRLASPQILFLLYTLCTIALFPLAKPGVIAQLSHWQ
                     LACLIFCGLNTLVGYGALAEAMARWQAAQVSAIITLTPLFTLFFSDLLSLAWPDFFAR
                     PMLNLLGYLGAFVVVAGAMYSAIGHRIWGGLRKHTTVVSQPRAGE"
     gene            complement(28208..28465)
                     /gene="rpmA"
                     /locus_tag="RHX21_000715"
     CDS             complement(28208..28465)
                     /gene="rpmA"
                     /locus_tag="RHX21_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HDV1985946.1"
                     /translation="MAHKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTK
                     FHAGANVGCGRDHTLFAKADGKVKFEVKGPKNRKFISIEAE"
     gene            complement(28486..28797)
                     /gene="rplU"
                     /locus_tag="RHX21_000716"
     CDS             complement(28486..28797)
                     /gene="rplU"
                     /locus_tag="RHX21_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015960603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HDV1985947.1"
                     /translation="MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETVEFAEVLMIANG
                     EEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGIS
                     A"
     gene            29056..30027
                     /gene="ispB"
                     /locus_tag="RHX21_000717"
     CDS             29056..30027
                     /gene="ispB"
                     /locus_tag="RHX21_000717"
                     /EC_number="2.5.1.90"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="octaprenyl diphosphate synthase"
                     /protein_id="HDV1985948.1"
                     /translation="MNLEKINELTAQDMAGVNAAILEQLNSDVQLINQLGYYIVSGGG
                     KRIRPMIAVLAARAVGYEGNAHVTIAALIEFIHTATLLHDDVVDESDMRRGKATANAA
                     FGNAASVLVGDFIYTRAFQMMTSLGSLKVLEVMSEAVNVIAEGEVLQLMNVNDPDITE
                     ENYMRVIYSKTARLFEAAAQCSGILAGCTPEEEKGLQDYGRYLGTAFQLIDDLLDYNA
                     DGEQLGKNVGDDLNEGKPTLPLLHAMHHGTPEQAQMIRTAIEQGNGRHLLEPVLEAMN
                     ACGSLEWTRQRAEEEADKAIAALQVLPDTPWREALIGLAHIAVQRDR"
     gene            30255..30533
                     /gene="sfsB"
                     /locus_tag="RHX21_000718"
     CDS             30255..30533
                     /gene="sfsB"
                     /locus_tag="RHX21_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SfsB"
                     /protein_id="HDV1985949.1"
                     /translation="MESNFIDWHPADIIAGLRKKGTSMAAESRRNGLSSSTLANALSR
                     PWPKGEMIIAKALGTDPWVIWPSRYHDPQTHEFIDRTQLMRSYTKPKK"
     gene            complement(30581..31840)
                     /gene="murA"
                     /locus_tag="RHX21_000719"
     CDS             complement(30581..31840)
                     /gene="murA"
                     /locus_tag="RHX21_000719"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDV1985950.1"
                     /translation="MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVEIQNV
                     PKLKDVDTSMKLLSQLGAKVERNGSVHIDARDVNVFCAPYDLVKTMRASIWALGPLVA
                     RFGQGQVSLPGGCTIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDK
                     VSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLITLGAKISGQGTDRIVIEGV
                     ERLGGGVYRVLPDRIETGTFLVAAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVG
                     EDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGTGFITETVFENRFMH
                     VPELSRMGAHAEIESNTVICHGVEKLSGAQVMATDLRASASLVLAGCIAEGTTVVDRI
                     YHIDRGYERIEDKLRALGANIERVKGE"
     gene            complement(31895..32149)
                     /gene="ibaG"
                     /locus_tag="RHX21_000720"
     CDS             complement(31895..32149)
                     /gene="ibaG"
                     /locus_tag="RHX21_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417657.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BolA family iron metabolism protein IbaG"
                     /protein_id="HDV1985951.1"
                     /translation="MENNEIQSVLMNALSLQEVHVSGDGSHFQVIAVGELFDGMSRVK
                     KQQTVYGPLMEYIADNRIHAVSIKAYTPAEWARDRKLNGF"
     gene            complement(32309..32602)
                     /gene="mlaB"
                     /locus_tag="RHX21_000721"
     CDS             complement(32309..32602)
                     /gene="mlaB"
                     /locus_tag="RHX21_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312097.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance protein MlaB"
                     /protein_id="HDV1985952.1"
                     /translation="MSESLSWMQTGDTLALSGELDQDVLLPLWEMREEAVKGITCIDL
                     SRVSRVDTGGLALLLHLIDLAKKQGNNVTLQGVNDKVYTLAKLYNLPADVLPR"
     gene            complement(32602..33237)
                     /gene="mlaC"
                     /locus_tag="RHX21_000722"
     CDS             complement(32602..33237)
                     /gene="mlaC"
                     /locus_tag="RHX21_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid-binding protein MlaC"
                     /protein_id="HDV1985953.1"
                     /translation="MFKRLMMVALLVIAPLSAATAADQTNPYKLMDEAAQKTFDRLKN
                     EQPQIRANPDYLRTIVDQELLPYVQVKYAGALVLGQYYKSATPAQREAYFAAFREYLK
                     QAYGQALAMYHGQTYQIAPEQPLGDKTIVPIRVTIIDPNGRPPVRLDFQWRKNSQTGN
                     WQAYDMIAEGVSMITTKQNEWGTLLRTKGIDGLTAQLKSISQQKITLEEKK"
     gene            complement(33256..33807)
                     /gene="mlaD"
                     /locus_tag="RHX21_000723"
     CDS             complement(33256..33807)
                     /gene="mlaD"
                     /locus_tag="RHX21_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipid asymmetry maintenance
                     protein MlaD"
                     /protein_id="HDV1985954.1"
                     /translation="MQTKKNEIWVGIFLLAALLAALFVCLKAANVTSIRTEPTYTLYA
                     TFDNIGGLKARSPVSIGGVVVGRVADITLDPKTYLPRVTLEIEQRYNHIPDTSSLSIR
                     TSGLLGEQYLALNVGFEDPELGTAILKDGDTIQDTKSAMVLEDLIGQFLYGSKGDDNK
                     NSGDAPAAAPGNNETTEPVGTTK"
     gene            complement(33812..34594)
                     /gene="mlaE"
                     /locus_tag="RHX21_000724"
     CDS             complement(33812..34594)
                     /gene="mlaE"
                     /locus_tag="RHX21_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014071945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance ABC transporter
                     permease subunit MlaE"
                     /protein_id="HDV1985955.1"
                     /translation="MLLNALASLGHKGIKTLRTFGRAGLMLFNALVGKPEFRKHAPLL
                     VRQLYNVGVLSMLIIVVSGVFIGMVLGLQGYLVLTTYSAETSLGMLVALSLLRELGPV
                     VAALLFAGRAGSALTAEIGLMRATEQLSSMEMMAVDPLRRVISPRFWAGVISLPLLTV
                     IFVAVGIWGGSLVGVSWKGIDSGFFWSAMQNAVDWRMDLVNCLIKSVVFAITVTWISL
                     FNGYDAIPTSAGISRATTRTVVHSSLAVLGLDFVLTALMFGN"
     gene            complement(34602..35411)
                     /gene="mlaF"
                     /locus_tag="RHX21_000725"
     CDS             complement(34602..35411)
                     /gene="mlaF"
                     /locus_tag="RHX21_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid ABC transporter ATP-binding protein
                     MlaF"
                     /protein_id="HDV1985956.1"
                     /translation="MEQSVANLVDMRDVSFTRGNRCIFDNISLTVPRGKITAIMGPSG
                     IGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLYTVRKRMSMLFQSGALFTDMNV
                     FDNVAYPLREHTQLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIA
                     LEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAWIL
                     ADKKIVAHGSAQALQANPDPRVRQFLDGIADGPVPFRYPAGDYHADLLPGS"
     gene            35621..36598
                     /locus_tag="RHX21_000726"
     CDS             35621..36598
                     /locus_tag="RHX21_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HDV1985957.1"
                     /translation="MLLATALLIVGLLLVVYSADRLVFAASILCRTFGIPPLIIGMTV
                     VSIGTSLPEIIVSLAASLHEQRDLAVGTALGSNIINILLILGLAALVRPFTVHSDVLR
                     RELPLMLLVSVVAGSVLYDGQLSRSDGIFLLFLAVLWLLFIVKLARQAERQGTDSLTR
                     EQLAELPRDGGLPVAFLWLGIALIIMPVATRMVVDNATVLANYFAISELTMGLTAIAI
                     GTSLPELATAIAGVRKGENDIAVGNIIGANIFNIVIVLGLPALITPGEIDPLAYSRDY
                     SVMLLVSIIFALLCWRRSPQPGRGVGVLLTGGFIVWLAMLYWLSPILVE"
     gene            36612..37598
                     /gene="kdsD"
                     /locus_tag="RHX21_000727"
     CDS             36612..37598
                     /gene="kdsD"
                     /locus_tag="RHX21_000727"
                     /EC_number="5.3.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-5-phosphate isomerase KdsD"
                     /protein_id="HDV1985958.1"
                     /translation="MSHVELQPGFDFQQAGKEVLAIERECLAELDQYINQNFTLACEK
                     MFWCKGKVVVMGMGKSGHIGRKMAATFASTGTPSFFVHPGEAAHGDLGMVTPQDVVIA
                     ISNSGESSEITALIPVLKRLHVPLICITGRPESSMARAADVHLCVKVAKEACPLGLAP
                     TSSTTATLVMGDALAVALLKARGFTAEDFALSHPGGALGRKLLLRVNDIMHTGDEIPH
                     VKKTASLRDALLEVTRKNLGMTVICDDNMMIEGIFTDGDLRRVFDMGVDVRQLSIADV
                     MTPGGIRVRPGILAVEALNLMQSRHITSVMVADGDHLLGVLHMHDLLRAGVV"
     gene            37619..38185
                     /gene="kdsC"
                     /locus_tag="RHX21_000728"
     CDS             37619..38185
                     /gene="kdsC"
                     /locus_tag="RHX21_000728"
                     /EC_number="3.1.3.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate-8-phosphatase KdsC"
                     /protein_id="HDV1985959.1"
                     /translation="MSKAGASLATCYGPVSADVIAKAENIRLLILDVDGVLSDGLIYM
                     GNNGEELKAFNVRDGYGIRCALTSDIEVAIITGRKAKLVEDRCATLGITHLYQGQSNK
                     LIAFSDLLEKLAIAPENVAYVGDDLIDWPVMEKVGLSVAVADAHPLLIPRADYVTRIA
                     GGRGAVREVCDLLLLAQGKLDEAKGQSI"
     gene            38182..38757
                     /gene="lptC"
                     /locus_tag="RHX21_000729"
     CDS             38182..38757
                     /gene="lptC"
                     /locus_tag="RHX21_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter periplasmic protein
                     LptC"
                     /protein_id="HDV1985960.1"
                     /translation="MSKARRWVIIVLSLAVLVMIGINMAEKDDTAQVVVNNNDPTYKS
                     EHTDTLVYNPEGALSYRLIAQHVEYYSDQAVSWFTQPVLTTFDKDKIPTWSVKADKAK
                     LTNDRMLYLYGHVEVNALVPDSQLRRITTDNAQINLVTQDVTSEDLVTLYGTTFNSSG
                     LKMRGNLRSKNAELIEKVRTSYEIQNKQTQP"
     gene            38726..39283
                     /gene="lptA"
                     /locus_tag="RHX21_000730"
     CDS             38726..39283
                     /gene="lptA"
                     /locus_tag="RHX21_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide ABC transporter
                     substrate-binding protein LptA"
                     /protein_id="HDV1985961.1"
                     /translation="MKFKTNKLSLNLVLASSLLAASIPAFAVTGDTDQPIHIESDQQS
                     LDMQGNVVTFTGNVIVTQGTIKINADKVVVTRPGGEQGKEVIDGYGKPATFYQMQDNG
                     KPVEGHASQMHYELAKDFVVLTGNAYLQQVDSNIKGDKITYLVKEQKMQAFSDKGKRV
                     TTVLVPSQLQDKNNKGQTPAQKKGN"
     gene            39290..40015
                     /gene="lptB"
                     /locus_tag="RHX21_000731"
     CDS             39290..40015
                     /gene="lptB"
                     /locus_tag="RHX21_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003861862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter ATP-binding protein"
                     /protein_id="HDV1985962.1"
                     /translation="MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTT
                     TFYMVVGIVPRDAGNIIIDDDDISLLPLHARARRGIGYLPQEASIFRRLSVYDNLMAV
                     LQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFIL
                     LDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAH
                     GTPTEILQDEHVKRVYLGEDFRL"
     gene            40063..41496
                     /gene="rpoN"
                     /locus_tag="RHX21_000732"
     CDS             40063..41496
                     /gene="rpoN"
                     /locus_tag="RHX21_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HDV1985963.1"
                     /translation="MKQGLQLRLSQQLAMTPQLQQAIRLLQLSTLELQQELQQALESN
                     PLLEQIDTHEEIDTRETQDSETLDTADALEQKEMPEELPLDASWDTIYTAGTPSGTSG
                     DYIDDELPVYQGETTQTLQDYLMWQVELTPFSDTDRAIATSIVDAVDDTGYLTVPLED
                     ILESMGDEEIDIDEVEAVLKRIQRFDPVGVAAKDLRDCLLIQLSQFDKTTPWLEEARL
                     IISDHLDLLANHDFRTLMRVTRLKEDVLKEAVNLIQSLDPRPGQSIQTGEPEYVIPDV
                     LVRKHNGHWTVELNSDSIPRLQINQHYASMCNNARNDGDSQFIRSNLQDAKWLIKSLE
                     SRNDTLLRVSRCIVEQQQAFFEQGEEYMKPMVLADIAQAVEMHESTISRVTTQKYLHS
                     PRGIFELKYFFSSHVNTEGGGEASSTAIRALVKKLIAAENPAKPLSDSKLTSLLSEQG
                     IMVARRTVAKYRESLSIPPSNQRKQLV"
     gene            41519..41806
                     /gene="hpf"
                     /locus_tag="RHX21_000733"
     CDS             41519..41806
                     /gene="hpf"
                     /locus_tag="RHX21_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome hibernation promoting factor"
                     /protein_id="HDV1985964.1"
                     /translation="MQLNITGNNVEITEALREFVTAKFAKLEQYFDRINQVYVVLKVE
                     KVTHTSDATLHVNGGEIHASAEGQDMYAAIDGLIDKLARQLTKHKDKLKQH"
     gene            41924..42415
                     /gene="ptsN"
                     /locus_tag="RHX21_000734"
     CDS             41924..42415
                     /gene="ptsN"
                     /locus_tag="RHX21_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS IIA-like nitrogen regulatory protein PtsN"
                     /protein_id="HDV1985965.1"
                     /translation="MTNNDTTLQLSSVLNRECTRSRVHCQSKKRALEIISELAAKQLS
                     LPPQVVFEAILTREKMGSTGIGNGIAIPHGKLEEDTLRAVGVFVQLETPIAFDAIDNQ
                     PVDLLFALLVPADQTKTHLHTLSLVAKRLADKTICRRLRAAQSDEELYQIITDTEGTP
                     DEA"
     gene            42461..43315
                     /gene="rapZ"
                     /locus_tag="RHX21_000735"
     CDS             42461..43315
                     /gene="rapZ"
                     /locus_tag="RHX21_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HDV1985966.1"
                     /translation="MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTL
                     ADREISAAVSIDVRNMPESPEIFEQAMSNLPDAFSPQLLFLDADRNTLIRRYSDTRRL
                     HPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKREREL
                     TMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNF
                     IYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRH
                     RTLEKRKP"
     gene            43312..43584
                     /gene="npr"
                     /locus_tag="RHX21_000736"
     CDS             43312..43584
                     /gene="npr"
                     /locus_tag="RHX21_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS phosphocarrier protein NPr"
                     /protein_id="HDV1985967.1"
                     /translation="MTVKQTVEITNKLGMHARPAMKLFELMQGFDAEVLLRNDEGTEA
                     EANSVIALLMLDSAKGRQIEVEATGPQEEEALAAVIALFNSGFDED"
     gene            43797..44429
                     /gene="yrbL"
                     /locus_tag="RHX21_000737"
     CDS             43797..44429
                     /gene="yrbL"
                     /locus_tag="RHX21_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoP regulatory network protein YrbL"
                     /protein_id="HDV1985968.1"
                     /translation="MIRLSEQNPLGTGRHRKCYAHPEDAQRCIKIVYHRGDGGDKEIR
                     RELKYYAHLGRRLKDWSGIPRYHGTVETDCGTGYVYDVIADFDGKPSITLTEFAEQCR
                     YEEDIAQLRQLLKQLKRYLQDNRIVTMSLKPQNILCHRISESEVIPVVCDNIGESTLI
                     PLATWSKWCCLRKQERLWKRFIAQPALAIALQKDLQPRESKTLALTSREA"
     gene            complement(44426..45154)
                     /gene="mtgA"
                     /locus_tag="RHX21_000738"
     CDS             complement(44426..45154)
                     /gene="mtgA"
                     /locus_tag="RHX21_000738"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monofunctional biosynthetic peptidoglycan
                     transglycosylase"
                     /protein_id="HDV1985969.1"
                     /translation="MSKSRLTVFSFVRRFLLRLMVVLAVFWGGGIALFSVAPVPFSAV
                     MVERQVSAWLHGNFRYVAHSDWVSMDQISPWMGLAVIAAEDQKFPEHWGFDVASIEKA
                     LAHNERNENRIRGASTISQQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTV
                     YLNIAEFGDGVFGVEAAAQRYFHKPASKLTRSEAALLAAVLPNPLRFKVSSPSGYVRS
                     RQAWILRQMYQLGGEPFMQQHQLD"
     gene            complement(45151..45804)
                     /gene="elbB"
                     /locus_tag="RHX21_000739"
     CDS             complement(45151..45804)
                     /gene="elbB"
                     /locus_tag="RHX21_000739"
                     /EC_number="4.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709007.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenoid biosynthesis glyoxalase ElbB"
                     /protein_id="HDV1985970.1"
                     /translation="MKKIGVILSGCGVYDGSEIHEAVLTLLAISRSGAQAVCFAPDKQ
                     QVDVINHLTGEAMTETRNVLIEAARITRGEIRPLAQADAAELDALIVPGGFGAAKNLS
                     NFATLGSECTVDRELKALAQAMHQAGKPLGFMCIAPAMLPKIFDFPLRLTIGTDIDTA
                     EVLEEMGAEHVPCPVDDIVVDEDNKIVTTPAYMLAQNIAEAASGIDKLVSRVLVLAE"
     gene            complement(46034..48370)
                     /gene="arcB"
                     /locus_tag="RHX21_000740"
     CDS             complement(46034..48370)
                     /gene="arcB"
                     /locus_tag="RHX21_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerobic respiration two-component sensor
                     histidine kinase ArcB"
                     /protein_id="HDV1985971.1"
                     /translation="MKQIRLLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTM
                     VLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQLEESRQRLSRLVQKLEEMRERDL
                     SLNVQLKDNIAQLNQEIAVREKAEAELQETFGQLKIEIKEREETQIQLEQQSSFLRSF
                     LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLVHLKPADVYSPEAAAKVIETDEK
                     VFRHNVSLTYEQWLDYPDGRKACFEIRKVPYYDRVGKRHGLMGFGRDITERKRYQDAL
                     ERASRDKTTFISTISHELRTPLNGIVGLSRILLDTELTAEQEKYLKTIHVSAVTLGNI
                     FNDIIDMDKMERRKVQLDNQPVDFTSFLADLENLSALQAQQKGLRFNLEPTLPLPHQV
                     ITDGTRLRQILWNLISNAVKFTQQGQVTVRVRYDEGDMLHFEVEDSGIGIPQDELDKI
                     FAMYYQVKDSHGGKPATGTGIGLAVSRRLAKNMGGDITVTSEQGKGSTFTLTIHAPSV
                     AEEVDDAFDEDDMPLPALNVLLVEDIELNVIVARSVLEKLGNSVDVAMTGKAALEMFK
                     PGEYDLVLLDIQLPDMTGLDISRELTKRYPREDLPPLVALTANVLKDKQEYLNAGMDD
                     VLSKPLSVPALTAMIKKFWDTQDDEESTVTTEENSKSEALLDIPMLEQYLELVGPKLI
                     TDGLAVFEKMMPGYVSVLESNLTAQDKKGIVEEGHKIKGAAGSVGLRHLQQLGQQIQS
                     PDLPAWEDNVGEWIEEMKEEWRHDVEVLKAWVAKATKK"
     gene            complement(48466..49395)
                     /locus_tag="RHX21_000741"
     CDS             complement(48466..49395)
                     /locus_tag="RHX21_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312117.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HDV1985972.1"
                     /translation="MQLQKLVNMFGGDLTRRYGQKVHKLTLHGGFSCPNRDGTIGRGG
                     CTFCNVASFADEAQQHRSIAEQLAHQANLVNRAKRYLAYFQAYTSTFAEVQVLRSMYQ
                     QAVSQANIVGLCVGTRPDCVPDAVLDLLCEYKDQGYEVWLELGLQTAHDKTLHRINRG
                     HDFACYQRTTQLARQRGLKVCSHLIVGLPGEGQAECLQTLERVVETGVDGIKLHPLHI
                     VKGSIMAKAWEAGRLNGIELEDYTLTAGEMIRHTPPEVIYHRISASARRPTLLAPLWC
                     ENRWTGMVELDRYLNEHGVQGSALERPWIPPTE"
     gene            50070..54530
                     /gene="gltB"
                     /locus_tag="RHX21_000742"
     CDS             50070..54530
                     /gene="gltB"
                     /locus_tag="RHX21_000742"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase large subunit"
                     /protein_id="HDV1985973.1"
                     /translation="MLYDKSLERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGA
                     ILADGKTGDGCGLLLQKPDRFFRIVAQERGWRLAKNYAVGMLFLNKDPELAAAARRIV
                     EEELQRETLSIVGWRDVPTNEGVLGEIALSSLPRIEQIFVNAPAGWRPRDMERRLFIA
                     RRRIEKRLEADKDFYVCSLSNLVNIYKGLCMPADLPRFYLDLADLRLESAICLFHQRF
                     STNTVPRWPLAQPFRYLAHNGEINTITGNRQWARARTYKFQTPLIPDLHDAAPFVNET
                     GSDSSSMDNMLELLLAGGMDIIRAMRLLVPPAWQNNPDMDPELRAFFDFNSMHMEPWD
                     GPAGIVMSDGRFAACNLDRNGLRPARYVITKDKLITCASEVGIWDYQPDEVVEKGRVG
                     PGELMVIDTRSGRILHSAETDDDLKSRHPYKEWMEKNVRRLVPFEDLPDEEVGSRELD
                     DDTLASYQKQFNYSAEELDSVIRVLGENGQEAVGSMGDDTPFAVLSSQPRIIYDYFRQ
                     QFAQVTNPPIDPLREAHVMSLATSIGREMNVFCEAEGQAHRLSFKSPILLYSDFKQLT
                     TMKEEHYRADTLDITFDVTKTTLEATVKELCDKAEKMVRSGTVLLVLSDRNIAKDRLP
                     VPAPMAVGAIQTRLVDQSLRCDANIIVETASARDPHHFAVLLGFGATAIYPYLAYETL
                     GRLVDTHAIAKDYRTVMLNYRNGINKGLYKIMSKMGISTIASYRCSKLFEAVGLHDDV
                     VGLCFQGAVSRIGGASFEDFQQDLLNLSKRAWLARKPISQGGLLKYVHGGEYHAYNPD
                     VVRTLQQAVQSGEYSDYQEYAKLVNERPATTLRDLLAITPGENAVNIADVEPASELFK
                     RFDTAAMSIGALSPEAHEALAEAMNSIGGNSNSGEGGEDPARYGTNKVSRIKQVASGR
                     FGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSVPGVTLISPPPHH
                     DIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLITIAGYDGGT
                     GASPLSSVKYAGCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIIKAAILGAE
                     SFGFGTGPMVALGCKYLRICHLNNCATGVATQDDKLRKNHYHGLPFKVTNYFEFIARE
                     TRELMAQLGVTRLVDLIGRTDLLKELDGFTAKQQKLALSKLLETAEPHPGKALYCTEN
                     NPPFDNGLLNAQLLQQAKPFVDERQSKTFWFDIRNTDRSVGASLSGYIAQTHGDQGLA
                     ADPIKAYFNGTAGQSFGVWNAGGVELYLTGDANDYVGKGMAGGLIAIRPPVGSAFRSH
                     EASIIGNTCLYGATGGRLYAAGRAGERFGVRNSGAITVVEGIGDNGCEYMTGGIVCIL
                     GKTGVNFGAGMTGGFAYVLDESGDFRKRVNPELVEVLSVDDLAIHEEHLRGLITEHVQ
                     HTGSQRGEEILANWSTFATKFALVKPKSSDVKALLGHRSRSAAELRVQAQ"
     gene            54543..55961
                     /gene="gltD"
                     /locus_tag="RHX21_000743"
     CDS             54543..55961
                     /gene="gltD"
                     /locus_tag="RHX21_000743"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001540975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase subunit GltD"
                     /protein_id="HDV1985974.1"
                     /translation="MSQNVYQFIDLQRVDPPKKPLKIRKIEFVEIYEPFSEGQAKAQA
                     DRCLSCGNPYCEWKCPVHNYIPNWLKLANEGRIFEAAELSHQTNTLPEVCGRVCPQDR
                     LCEGSCTLNDEFGAVTIGNIERYINDKAFEMGWRPDMSGVKQTGKKVAIIGAGPAGLA
                     CADVLTRNGVKAVVFDRHPEIGGLLTFGIPAFKLEKEVMTRRREIFTGMGIEFKLNTE
                     VGRDVQLDDLLSDYDAVFLGVGTYQSMRGGLENEDADGVYAALPFLIANTKQLMGFGE
                     TRDEPFVSMEGKRVVVLGGGDTAMDCVRTSVRQGAKHVTCAYRRDEENMPGSRREVKN
                     AREEGVEFKFNVQPLGIEVNGNGKVSGVKMVRTEMGEPDAKGRRRAEIVAGSEHIVPA
                     DAVIMAFGFRPHNMEWLAKHSVELDSQGRIIAPEGSDNAFQTSNPKIFAGGDIVRGSD
                     LVVTAIAEGRKAADGIMNWLEV"
     gene            56145..57272
                     /locus_tag="RHX21_000744"
     CDS             56145..57272
                     /locus_tag="RHX21_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1016 family protein"
                     /protein_id="HDV1985975.1"
                     /translation="MESLSERTSTGYQQIHDGIIHLVDSARTETVRSVNALMTATYWE
                     IGRRIVEFEQGGEARAAYGAQLIKRLSKDLSLRYKRGFSAKNLRQMRLFYLFFQHVEI
                     RQTVSGELTPLGIPQTPSAEFPSAKIWQTLSAKSFPLPWSTYVRLLSVKNADARSFYE
                     KETLRCGWSVRQLERQIATQFYERILLSHDKSAMLQQHAPTETHILPQQAIRDPFVLE
                     FLELKDEYSESDFEEALINHLMDFMLELGDDFAFVGRQRRLRIDDNWFRVDLLFFHRR
                     LRCLLIVDLKVGKFSYSDAGQMNMYLNYAKEHWTLPDENPPIGLVLCAEKGAGEAHYA
                     LAGLPNTVLASEYKMQLPDEKRLADELVRTQAVLEEGYRRR"
     gene            complement(57332..57796)
                     /locus_tag="RHX21_000745"
     CDS             complement(57332..57796)
                     /locus_tag="RHX21_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HDV1985976.1"
                     /translation="MMMGEVQSLPSAGLHPALQDALTLALAARPQEKAPGRYELQGDN
                     IFMNVMTFNTQSPVEKKAELHEQYIDIQLLLNGEERILFGMAGTARQCEEFHHEDDYQ
                     LCSAIENEQTIILKPGMFAVFMPGEPHKPGCVVGEPGEIKKVVVKVKADLMA"
     gene            complement(57793..58668)
                     /gene="nanK"
                     /locus_tag="RHX21_000746"
     CDS             complement(57793..58668)
                     /gene="nanK"
                     /locus_tag="RHX21_000746"
                     /EC_number="2.7.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312122.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine kinase"
                     /protein_id="HDV1985977.1"
                     /translation="MTTLAIDIGGTKLAAALIGADGQIRDRRELPTPASQTPEALRDA
                     LSALVSPLQAHAQRVAIASTGIIRDGSLLALNPHNLGGLLHFPLVKTLEQLTNLPTIA
                     INDAQAAAWAEYQALEGDVTEMVFITVSTGVGGGVVSGGKLLTGPGGLAGHIGHTLAD
                     PHGPVCGCGRTGCVEAIASGRGIAAAAQGELMGADARTIFTRAGQGDEQAQQLIHRSA
                     HVLARLIADIKATTDCQCVVVGGSVGLAEGYLALVETYLAQEPAAFHVDLLAAHYRHD
                     AGLLGAALLAQGEKL"
     gene            complement(58665..59354)
                     /locus_tag="RHX21_000747"
     CDS             complement(58665..59354)
                     /locus_tag="RHX21_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDV1985978.1"
                     /translation="MSLLAQLDQKIAANGGLIVSCQPVPDSPLDKPEIVAAMALAAEQ
                     AGAVAIRIEGVANLQATRAVVSVPIIGIVKRDLEDSPVRITAYIEDVDALAQAGADII
                     AIDGTDRPRPVPVETLLARIHHHGLLAMTDCSTPEDGLACQKLGAEIIGTTLSGYTTP
                     ETPEEPDLALVKTLSDAGCRVIAEGRYNTPAQAADAMRHGAWAVTVGSAITRLEHICQ
                     WYNTAMKKAVL"
     gene            complement(59402..60892)
                     /gene="nanT"
                     /locus_tag="RHX21_000748"
     CDS             complement(59402..60892)
                     /gene="nanT"
                     /locus_tag="RHX21_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312124.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialic acid transporter NanT"
                     /protein_id="HDV1985979.1"
                     /translation="MSTTTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLT
                     EVQGEFGLTTVQAASLISAAFISRWFGGLMLGAMGDRYGRRLAMVTSIVLFSAGTLAC
                     GFAPGYITMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVA
                     AQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHAGKAPVRTMVDILY
                     RGEHRIANIVMTLAAATALWFCFAGNLQNAAIVAVLGLLCAAIFISFMVQSTGKRWPT
                     GVMLMVVVLFAFLYSWPIQALLPTYLKTDLAYNPHTVANVLFFSGFGAAVGCCVGGFL
                     GDWLGTRKAYVCSLLASQLLIIPVFAIGGANVWVLGLLLFFQQMLGQGIAGILPKLIG
                     GYFDTDQRAAGLGFTYNVGALGGALAPIIGALIAQRLDLGTALASLSFSLTFVVILLI
                     GLDMPSRVQRWLRPEALRTHDAIDGKPFSGAVPFGSPKNDLVKTKS"
     gene            complement(61001..61894)
                     /gene="nanA"
                     /locus_tag="RHX21_000749"
     CDS             complement(61001..61894)
                     /gene="nanA"
                     /locus_tag="RHX21_000749"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HDV1985980.1"
                     /translation="MATNLRGVMAALLTPFDQQQALDKASLRRLVQFNIQQGIDGLYV
                     GGSTGEAFVQSLSEREQVLEIVAEEAKGQIKLIAHVGCVSTAESQQLAASAKRYGFDA
                     VSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVYNIPALSGVKLTLDQINTLVTLPG
                     VGALKQTSGDLYQMEQIRREHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQ
                     GIVKALKEGDIQTAQKLQTECNKVIDLLIKTGVFRGLKTVLHYMDVVSVPLCRKPFGP
                     VDEKYLPELKALAQQLMQERG"
     gene            complement(62016..62807)
                     /gene="nanR"
                     /locus_tag="RHX21_000750"
     CDS             complement(62016..62807)
                     /gene="nanR"
                     /locus_tag="RHX21_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417693.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NanR"
                     /protein_id="HDV1985981.1"
                     /translation="MGLMNAFDSQTEDSSPAIGRNLRSRPLARKKLSEMVEEELEQMI
                     RRREFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADT
                     IIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQ
                     SLDNNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVTDQALHEHNNVS
                     YQQHIAIVDAIRRHDPDEADRALQSHLNSVSATWHAFGQTTNKKK"
     gene            63187..64554
                     /gene="dcuC"
                     /locus_tag="RHX21_000751"
     CDS             63187..64554
                     /gene="dcuC"
                     /locus_tag="RHX21_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuC"
                     /protein_id="HDV1985982.1"
                     /translation="MFGIIISVIVLITMGYLILKNYKPQVLLAAAGIFLMMCGVWLGF
                     GGVLDPAKSSGYLIVDIYNEILRMLSNRIAGLGLSIMAVGGYARYMERTGASRAMVSL
                     LSRPLKLIRSPYIILSATYVIGQIMAQFITSASGLGMLLMVTLFPTLVSLGVSRLSAV
                     AVIATTMSIEWGILETNSIFAAQVAGMKIATYFFHYQLPVASCVIISVAISHFFVQRA
                     FDKKDKNINHEQAELKALDNVPPLYYAILPVMPLILMLGSLFLAHIGLMQSELHLVVV
                     MLLSLTVTMFVEFFRKHNLRETMDDVQAFFDGMGTQFANVVTLVVAGEIFAKGLTTIG
                     TVDAVIRGAEHSGLGGIGVMIIMALVIAICAIVMGSGNAPFMSFASLIPNIAAGLHVP
                     AVVMIMPMHFATTLARAVSPITAVVVVTSGIAGVSPFAVVKRTAIPMAVGFVVNMIAT
                     ITLFY"
     gene            complement(64597..65094)
                     /gene="sspB"
                     /locus_tag="RHX21_000752"
     CDS             complement(64597..65094)
                     /gene="sspB"
                     /locus_tag="RHX21_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP protease specificity-enhancing factor"
                     /protein_id="HDV1985983.1"
                     /translation="MDLSQLTPRRPYLLRAFYEWLLDNQLTPHLVVDVTLPGVQVPME
                     YARDGQIVLNIAPRAVGNLELANDEVRFNARFGGIPRQVSVPLAAVLAIYARENGAGT
                     MFEPEAAYDEDTSIMNDEEASADNETVMSVIDGDKPDHDDDTHPDDELPQPPRGGRPA
                     LRVVK"
     gene            complement(65100..65738)
                     /gene="sspA"
                     /locus_tag="RHX21_000753"
     CDS             complement(65100..65738)
                     /gene="sspA"
                     /locus_tag="RHX21_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stringent starvation protein A"
                     /protein_id="HDV1985984.1"
                     /translation="MAVAANKRSVMTLFSGPTDIYSHQVRIVLAEKGVSFEIEHVEKD
                     NPPQDLIDLNPNQSVPTLVDRELTLWESRIIMEYLDERFPHPPLMPVYPVARGESRLY
                     MHRIEKDWYTLMNTIINGSASEADAARKQLREELLAIAPVFGQKPYFLSDEFSLVDCY
                     LAPLLWRLPQLGIEFSGPGAKELKGYMTRVFERDSFLASLTEAEREMRLGRS"
     gene            complement(66133..66525)
                     /gene="rpsI"
                     /locus_tag="RHX21_000754"
     CDS             complement(66133..66525)
                     /gene="rpsI"
                     /locus_tag="RHX21_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDV1985985.1"
                     /translation="MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETA
                     RMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRSELRKAG
                     FVTRDARQVERKKVGLRKARRRPQFSKR"
     gene            complement(66541..66969)
                     /gene="rplM"
                     /locus_tag="RHX21_000755"
     CDS             complement(66541..66969)
                     /gene="rplM"
                     /locus_tag="RHX21_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010847760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HDV1985986.1"
                     /translation="MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEY
                     TPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERVIE
                     IAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI"
     gene            complement(67188..68315)
                     /gene="zapE"
                     /locus_tag="RHX21_000756"
     CDS             complement(67188..68315)
                     /gene="zapE"
                     /locus_tag="RHX21_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapE"
                     /protein_id="HDV1985987.1"
                     /translation="MQSVTPTSQYLKALNEGSHQPDDVQKEAVSRLEIIYQELINSRP
                     PAPRTSGLMARVGKLWGKREDTKHTPVRGLYMWGGVGRGKTWLMDLFYQSLPGERKQR
                     LHFHRFMLRVHEELTALQGQTDPLEIIADRFKAETDVLCFDEFFVSDITDAMLLGGLM
                     KALFARGITLVATSNIPPDELYRNGLQRARFLPAIDAIKQHCDVMNVDAGVDYRLRTL
                     TQAHLWLSPLNDETRAQMDKLWLALAGAKRENSPTLEINHRPLATMGVENQTLAVSFT
                     TLCVDARSQHDYIALSRLFHTVMLFDVPVMTRLMESEARRFIALVDEFYERHVKLVVS
                     AEVPLYEIYQGDRLKFEFQRCLSRLQEMQSEEYLKREHLAG"
     gene            68509..68907
                     /locus_tag="RHX21_000757"
     CDS             68509..68907
                     /locus_tag="RHX21_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1043 family protein"
                     /protein_id="HDV1985988.1"
                     /translation="MTWEYALIGLVVGIIIGAVAMRFGNRKLRQQQALQYELEKNKAE
                     LDEYREELVSHFARSAELLDTMAHDYRQLYQHMAKSSSSLLPELSAEANPFRNRLAES
                     EASNDQAPVQMPRDYSEGASGLLRTGAKRD"
     gene            69061..70428
                     /gene="degQ"
                     /locus_tag="RHX21_000758"
     CDS             69061..70428
                     /gene="degQ"
                     /locus_tag="RHX21_000758"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine endoprotease DegQ"
                     /protein_id="HDV1985989.1"
                     /translation="MKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAP
                     MLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASKG
                     YVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSD
                     KLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGAL
                     LNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEM
                     SADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIAT
                     TEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGI
                     KIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGNESI
                     YLLMR"
     gene            70518..71585
                     /gene="degS"
                     /locus_tag="RHX21_000759"
     CDS             70518..71585
                     /gene="degS"
                     /locus_tag="RHX21_000759"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane-stress sensor serine
                     endopeptidase DegS"
                     /protein_id="HDV1985990.1"
                     /translation="MFVKLLRSVAIGLIVGAILLVAMPSLRSLNPLSTPQFDSTDETP
                     ASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD
                     QIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGN
                     PYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTL
                     SFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQSGGI
                     DQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVV
                     VMRDDKQLTLQVTIQEYPATN"
     gene            complement(71647..72585)
                     /gene="mdh"
                     /locus_tag="RHX21_000760"
     CDS             complement(71647..72585)
                     /gene="mdh"
                     /locus_tag="RHX21_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase"
                     /protein_id="HDV1985991.1"
                     /translation="MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAV
                     DLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLV
                     QQVAKTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAE
                     LKGKQPGEVEVPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKA
                     GGGSATLSMGQAAARFGLSLVRALQGEQGVVECAYVEGDGQYARFFSQPLLLGKNGVE
                     ERKSIGTLSAFEQNALEGMLDTLKKDIALGEEFVNK"
     gene            73020..73490
                     /gene="argR"
                     /locus_tag="RHX21_000761"
     CDS             73020..73490
                     /gene="argR"
                     /locus_tag="RHX21_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ArgR"
                     /protein_id="HDV1985992.1"
                     /translation="MRSSAKQEELVKAFKALLKEEKFSSQGEIVAALQEQGFDNINQS
                     KVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSP
                     GAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPANGFTVKDLYEAILELFDQEL"
BASE COUNT        18087 a        19822 c        18186 g        17611 t
ORIGIN      
        1 cctgataagc gaagcgcatc aggcattgtg taggcagcag aaatgtcgga taaggcaccg
       61 ctgattactg atacaccggc agtaaattaa agctcgataa aatatggacc agtgcgttgc
      121 caacgccaaa caccagaatc agcgtaatca tcggcttgcc gccccagacg cggaatttcg
      181 ggctgccaaa gcgtttacgc gatgcgcggg ctaacagcgc cggaacaatt gccgcccaga
      241 tggtagctgc taaaccagca taaccaatgg cgtacaggaa tccgttcggg aacagtagac
      301 cacccacaac aggcggggca aaggtcagca atgccgtttt caagcgcccc agggctgagt
      361 catcgaaacc aaacagatct gccagatagt caaacaaacc cagcgttacg ccaaggaacg
      421 aactcgctac cgcaaagttt gagaacacga ccagcagaag gtccaggcta cggctgttca
      481 gcacgccgct taatgcctgt accagcacat caatattacc gcccttctct gcaataccga
      541 taaactccgg acgcgggatg ttacccatcg tcgccagcaa ccagatggta tacagcgcca
      601 gtgccatcag cgtaccgtac accaggcatt tcacaatggt tttcggatct ttgccgtaat
      661 acttcatcag gcttggcacg ttaccgtgat aaccaaacga cgccaggcag aacggcaatg
      721 tcatcagcag atacggcgca taagatgcat tgctttctgc aacgttgaac aatgtcgcag
      781 gctgcacatg ccccaacagg ctgccaaagg tgaggaagaa ggtaatgact ttcgccccca
      841 gcacaatcgc cgtcatgcgg ctgacggcct tagtactcaa ccacaccaca aacgctacca
      901 gcagtgcaaa accaaaaccc gccgcccgtg ccgggacgtt tagcgacatc tctgcgaagg
      961 tgtgatgcag aattgaacca ctggcagaaa tataggcata ggtcaggata tagagcacaa
     1021 aggcaatgga aataccgttg accacgttcc agcctttgcc cagcaaatct ttggtgatgg
     1081 tgtcaaaact cgaaccgatt cggtaattca ggttagcttc cagaatcatc aagccggaat
     1141 gcagcataca gaaccaggta aagatcagcg ccgccattga ccagaaaaac cacgccccgg
     1201 acatgaccac tggcagagaa aacatccctg cgccaataat ggtgccgccg ataatcacca
     1261 cgccgccaag cagcgacggt gacgtttggg tggtggttag tgttgccatg agggcttctc
     1321 tccagtgaaa aatagtgcga ctgcgttgtt atgcattgca ctgtaccagt acacgagtac
     1381 aaaagacaga aaaaaagccc cgatggtaaa aatcggggct gtatatatta ttttacagat
     1441 tgtgttcgct gttcagcgat gattacgcat caccaccgaa acgacgacga ccggtagagt
     1501 catcacgacg cggagcgcgg ccttcacgac gttcgccgct aaaacgacga ccatcaccac
     1561 ggccaccttc acggcgttca ccactgaagt tacgaccgcc ttcacgacgt tcgccaccga
     1621 aaccacgacc accgccacga cgctcaccgc cagtatgcgg ctgtgcatcg cccagtaact
     1681 gcatgttcat cggcttgttg agaatgcgag tacgcgtaaa gtgttgcagc acttcacccg
     1741 gcataccttt cggcagttcg atggtggagt gagaagcaaa cagcttgatg ttaccaatgt
     1801 aacggctgct gatgtcgcct tcgttagcaa tcgcaccaac gatatgacga acttcaacac
     1861 catcatcgcg gcccacttca atgcggtaca gctgcatatc gccaacatca cgacgttcac
     1921 gacgcggacg atcttcacgg tcaccacgcg ggccacggtc gttacgatcg cgcggaccac
     1981 ggtcatcacg gtcacggaat tcacgtttcg gacgcatcgg cgcatctggc ggtacgatca
     2041 gagtacgttc accctgtgcc attttcagca gtgccgcagc cagagtttcg agatccagct
     2101 cttcaccttc tgcagtcggc tgaattttgc tcagcagtgc gcggtattga tccagatcgc
     2161 tgctttccag ctgctgctgt actttagcgg cgaatttttc cagacggcgt ttgcccagca
     2221 gttctgcgtt cggcagttct acttccggaa tagtcagctt catagtacgt tcaatgttgc
     2281 gcagcagacg acgctcgcgg ttctcaacga acagcagcgc gcggccagca cgacccgcac
     2341 gaccggtacg accgatacgg tgaacgtaag actcagaatc catcgggata tcgtagttaa
     2401 ctaccaggct gatacgctca acgtccaggc cacgggctgc aacgtcggtc gcaatcagga
     2461 tgtccagacg accatctttc aggcgttcca gtgtctgttc acgaagcgcc tggttcatgt
     2521 caccgttcag cgcggcgctg ttgtagccgt tacgctcaag agcttcagcc acttccagag
     2581 tcgcgttttt ggtacgaacg aagataatcg ccgcatcaaa atcttccgct tccaggaaac
     2641 gtaccagtgc ttcgtttttg cgcatacccc agacagtcca gtagctctgg ctgatgtcag
     2701 gacgggtagt cacgctggac tgaatgcgca cttcctgcgg ctctttcata aagcggcggg
     2761 taatgcgacg aatcgcttcc ggcatggttg cagagaacag agcggtctga tgaccttccg
     2821 ggatctgcgc cataatggtt tcaacgtctt cgatgaagcc catgcgcagc atttcgtcag
     2881 cttcatccag aaccagaccg ctcagtttag agaggtccag agtgccacgt ttcaggtggt
     2941 ccagcagacg gcccggagta ccgacaacga tctgcggccc ctgacgcagg gcgcgtaatt
     3001 gcacgtcata acgctggccg ccgtacagag caaccacatt tacgccgcgc atgtgtttag
     3061 agaaatccgt cattgcttca gcaacctgta ccgccagttc gcgggtcggt gccagcacca
     3121 gaatctgtgg tgctttcagc tcaggatcaa gattctgcaa cagaggtaaa gagaatgctg
     3181 cagtttttcc gctccccgtc tgggccatac ccagaacgtc gcggccattc agcagatgtg
     3241 gaatacactc tgcctgaatt ggagatggtt tttcgtaacc cagatcgtta agggcttcaa
     3301 ggataggagc cttcaggccc agatctgcaa aagtggtttc gaattcagcc atgtagtacg
     3361 tgtgcctcaa aattaatggc ggccagtcta cataactcat catgaaattg atcagcaatt
     3421 ttcattgaaa agtgtgaacc ggctcaaagt aggtgtatta acgaacaaca acgccctcac
     3481 ccgttaaggt gatggcaatc aaaaaagatt acgggctgat gtgtacgtca gctattgctg
     3541 gtccgattct gccaggtcat cttggtcctg gcccaggagc gataattcca acaatgcgta
     3601 tcggtgctca acaaagttat gaacgttgtt ggcaaccgcc agtttgaaca gtgccgtggc
     3661 gctgtccaaa tcccccagac ttaggtagta cttacctaaa tagaagttgg tttcactgag
     3721 atgctcagcg agcgaggtgt tatccgttgc gtccgccttg agcctttcca ttaacgtttg
     3781 ttcgctaatg ttgcccaggt agaactcgac aatgttccat ccccactgtt ccttatccga
     3841 tttttcgaag tgctgtttca acacttcttt agcctgcttc tcatcgagct tctgctcggc
     3901 gagataaagc cacagactac ggaaaggatc attgggatcg tcttgataaa acgccagcag
     3961 atcatcttgc gctaacttgt cacgaccgcc gtaatataat gcgatcccgc gattcaagtg
     4021 cgcgtagttg taagttggat caagctcaag tacagaatca aacgcttcat aggcagcatc
     4081 aaaattgcct gcctgcgtta aatatatgcc taagtaattg aatacttcag gcatatccgg
     4141 tcggattgcc agcgcttgcg aaaaatcgtt acgcgctaat gccctcagac cgagactatc
     4201 atacaacact ccgcgctcat ataaaagctg tgcgcgttcg tcatcggtta aagcccgact
     4261 ggcaaggatt tgttccatac gtgccagaat cacttcctgc tgtaaagtcg gttgcaatgg
     4321 taccgcgagg acttcacttt tacgccagga agtattactg catcctgcaa gcgtaagtgc
     4381 tgtcgcaacg aaacaccagc gcaaaaaagg cttcatttcc cactcccgaa gaccacggtt
     4441 gaatgaacgt cctgttcccg gttgctaaca aggcgtcctg cccggttaaa agccccccgc
     4501 cgcagcggag ggcaaatggc aaccttactc gccctgttca gcagccggag cttccggtgc
     4561 tgcagcaggt tgagactgct cagtcgcttc tttaatgctc agacggatac ggccctggcg
     4621 atcaacttcc agaactttca ccggtacttc ctgacccatc tgcaggtaat cggtcacttt
     4681 ctcaacgcgt ttgtcagcga tttgagagat gtggaccaga ccttctttac cgccgccgat
     4741 ggcaacaaat gcgccaaagt caacgatacg ggtcacttta ccagtgtaga cgcggcccac
     4801 ttcgatttct gcagtgatct cttcgatacg acgaatagca tgtttcgctt tctcgccgtc
     4861 ggtcgctgcg atcttcacag taccgtcatc ttcgatttcg atggtagtgc cagtttcttc
     4921 ggtcagggca cggataacag agccgccttt accgataacg tctttgatct tatccgggtt
     4981 gatcttgatg gtatggatac gcggtgcgaa ctcagagata tcgccacgcg gcgcgttgat
     5041 cgcctgttcc attacgccca ggatatgcag acgcgcacct ttagcctggt tcagcgcaac
     5101 ctgcatgatc tctttggtga taccttcaat tttgatatcc atctgcagtg cagagatacc
     5161 gtcgcgggaa cctgcaactt tgaagtccat atcgcccagg tgatcttcgt cgcccaaaat
     5221 gtcagacagt acaacgtagt tgtcgccttc tttcaccaga cccattgcga tacccgcaac
     5281 ggcagctttg attggcacac ctgcgtccat cagcgccaga gacgcgccgc acacggaagc
     5341 catagaagaa gaaccgttgg attcggtgat ttcagacact acacgtacgg tgtacgggaa
     5401 tttgtccata tccggcatga ctgccagcac gccgcgcttc gccagacgac cgtgaccaat
     5461 ttcacgacgc ttcggagaac cgaccatgcc ggtttcgcct acggagtacg gagggaagtt
     5521 gtagtggaac aggaaggtat cggtacgttc gcccatcagt tcatcaagaa cctgcgcgtc
     5581 acgagcggta cccagcgttg cagtaaccag tgcctgcgtt tcaccgcggg tgaacagcgc
     5641 agaaccgtga gtacgcggca gcacgccagt acgcacatcc agaccacgga tcatatcttt
     5701 ttcacgaccg tcgatacgcg gttcgcctgc cagtacgcgg ctacgaacaa cgtttttctc
     5761 gatagcgtgc agaatttcac ccagttcgtt ttcgtccagg gtttcgtctt cagcaagcag
     5821 cgtcgcgatg gtttcagatt tgatgacatc aacctgcgca taacgctctt gtttgtcggt
     5881 gatgcggtaa gcatcgctca ggcgagcttc agccagtgca gcaacgcgcg cgttcagcgc
     5941 ttcgtttacc ggctccggct gccagtccca acgtggttta ccggcttctt tcaccagttc
     6001 attgatgttc tgaataacaa cctgctgttg ttcatgaccg aacactactg cgcccagcat
     6061 ctggtcttcg ctcagcagtt cagcttcaga ttcaaccatc agaacagcgg cttcagtacc
     6121 ggcaacaacc agatccagtt tgctctcttt cagctcgtcc tgagtcgggt tcagtacgta
     6181 ctggtcattg atgtaaccta cgcgagcagc accaatcgga ccattgaacg gaataccaga
     6241 cagagacagt gctgcggaag caccaatcat cgcgacgata tccgggttaa cttgcgggtt
     6301 aacagaaacc acggtggcga taacctgaac ttcgttgacg aagccttccg ggaacagcgg
     6361 gcgaatcggg cggtcaatca gacgcgcgat cagggtttcg ccttcgcttg ggcggccttc
     6421 acgacggaag aagctacccg ggatacgacc agcagcgtag gtacgctcct gatagttaac
     6481 ggtcagtggg aagaagtcct gacctggttt ggcttttttc tggccaacaa cggtaacaaa
     6541 taccgcggtg tcatccatgc taaccataac agcggcagta gcctgacgag ccatcatgcc
     6601 ggtttccaga gtcacggtgt gttggccgta ctggaattta cgaacgatcg gattaagcaa
     6661 tgtaatatcc tttctctttc ttagacagta ccttacggca ctggtgttaa tacccgatct
     6721 tctgcgcatc ctcgcgacta atgacaaccc taacccagct ctatgtgggt aaagcctctc
     6781 attagccgcg cgaacctctg caacggaaga tcattcatag caacaataca ttagtttcca
     6841 gtgaattgct gccgtcagct tgaaaaaagg ggccactcag gccccctttt ctgaaactcg
     6901 caagaattag cgacgcagac ccaggcgctc gatgagctgg gtgtaacgtg ctacgtcttt
     6961 acgtttcagg tagtcgagca gtttacgacg ctgagaaacc atgcgcagca gaccacgacg
     7021 gctgtggtga tcttttttgt gctctgcaaa gtggccctgc aggtggttga tctgtgcagt
     7081 cagcagtgct acctgaactt cggtagaacc ggtgtcgttt gcgtcacgac caaactcaga
     7141 aacgatttta gctgttgctt cagtacttag agacatttta aaactccaaa gtatatagaa
     7201 tgaaaggacg ccgatctcta attcagcgat cccagtgtac gttacgcaaa gtgttaaaca
     7261 atttacgcga cgttaagcgg cagtattcta ctcgtagcga cctgttatcg caagacggtt
     7321 aacattacgc cgggtattca accaccaggc gacgaggcgc aacgcggcct tcatcgtcaa
     7381 tttcgcccat accgataaat ttgccgttct caccttctgt aacgcgaacc agtccttcca
     7441 gcggcgcacc ggatgtacga actgggttac catttttgaa gtaaacagaa gacgttaacg
     7501 gaagattcac caccgggtag tccgaagctg gactgtccat tggcatcagt aatggatcaa
     7561 gtaactccgc agccggaata tcctgctgtt cggcttgttc gaccagttca cgcagatgtt
     7621 ccagggtcac catccgttca accggatatt tacttaccgc cagacgacgc aggtaaataa
     7681 catgcgcgcc acaaccgagt ttttcaccca ggtcatcaat gatggtgcgg atataagtgc
     7741 cttttgagca gtgaatttcc agctccagct cattgccttc gtggcgaata aacagcaatt
     7801 cataaacggt aatcgggcgc gcttcacgcg gtacttcaat gccctgacgc gcatattcgt
     7861 acagtttttt accctgatat ttcagtgctg aatacatcga agggatctgt tcgatatcgc
     7921 cacggaaagt atccagcgcc gccgccagtt gctctgcgct aaaggttacc ggacgttctt
     7981 caacgatttg tccgtcggca tcagaagtat cggtacgctg tccaagacgc gcaatgaccc
     8041 gatagcgttt gtcggagtcc agcagatact gggaaaactt cgtcgcttcc ccgaggcaaa
     8101 ttggcaacat gccagttgcc agcgggtcca gcgcaccggt atgcccggca cggttggcgt
     8161 tataaatccg tttcactttt tgcagcgcat cattgctgga cataccctgc ggtttatcca
     8221 gcaacaaaac gccgttaatg tcgcgaccgc gacgacgagg acgactcatt agtcctcctt
     8281 gctgtcgtcc gggttaacac gacgttcttc gtcatgtttg accacgctgg tcaccaggtt
     8341 tgacatgcgc atcccttcaa ccagagagtt gtcgtagaag aaggtcagtt ccggcacgat
     8401 acgcaggcgc atcgctttcc ccagcaggct gcggatgaaa ccagaagctt cttgcaacgc
     8461 tttgatgccc gctttaaccg cgtcttcatc tttgtcgttg aggaacgtca catatacttt
     8521 ggcatacgcc aggtcgcgag acatttcgac accggaaacg gtggtcatca tgcccaggcg
     8581 aggatcttta atttcacgct gcaggatgag agcgatctct ttttgcattt cctgcgctac
     8641 gcgctgcggg cgaccaaatt ctttcgccat aataaattct cctgacaaaa aaggggctgt
     8701 tagccccttt ttaaaattaa tttcaggtgg aagggctgtt cacgttggcc tgataagacg
     8761 cgccagcgtc acatcaggca atccatgccg gatgcggcat aaacgcctta tcccgcatgg
     8821 aaccctaaaa accttaagcg atggtacgtt ggatctcgat gatttcgaat acttcgatca
     8881 catcgccagt gcggacgtcg ttgtagttct taacgccgat accacattcc ataccgttac
     8941 ggacttcgtt aacgtcatct ttgaagcggc gcagggactc cagctcgcct tcgtagataa
     9001 ccacgttgtc acgcagaacg cggatcgggt tgtgacgttt aaccacacct tcgataacca
     9061 tacagcctgc gatggcacca aatttcggcg atttgaacac gtcacgaact tccgccagac
     9121 cgataatctg ctgtttcagt tccggagaca gcataccgct catcgccgct ttcacttcgt
     9181 caatcaggtt atagatgacg gagtagtaac gcagatccag gctttccgct tcaatcactt
     9241 tacgtgcaga ggcatcagca cgtacgttga agccaaccag gatggcgttg gacgccgcag
     9301 ccagggtggc gtcggtttcg gtgataccac ctacgccaga accgatgatc ttcactttaa
     9361 cttcgtcagt agacagtttc agcaaggagt cggagatcgc ttccacagaa ccctgtacgt
     9421 ctgccttcag gacgatgttc acttcgtgaa cttcgccttc ggtcatgttg gcgaacatgt
     9481 tctcgagttt agatttctgc tgacgcgcca gtttaacttc gcggaattta ccctgacgat
     9541 acagtgcaac ttcacgcgct ttcttctcgt cacgtacaac ggtaacttca tcacccgcag
     9601 ccggtacgcc ggacaggccg aggatttcca ccggaatgga cggacccgct tccagcactt
     9661 cctgacccag ttcgttacgc atcgcacgaa cacgaccgta ttcgaagcca cacagaacga
     9721 tatcgccctt gtgcagagta ccttcacgta ccagaacggt agcaaccgga ccacgacctt
     9781 tatcgaggaa ggattcgata accgcaccgc tcgccatacc tttacgtacc gctttcagct
     9841 ccagaacttc cgcctgcagc aggatagcgt ccagcagttc atcgatgccg gtacccgctt
     9901 tcgcagatac gtgtacgaac tggctttcac cgccccactc ttccggcagg atgccatact
     9961 gggagagttc gttcttaaca cgatccggat cggcttctgg tttatcaatc ttgttcactg
    10021 caaccaccac cggtacctgc gccgctttcg cgtgctggat tgcttcgatg gtctgcggca
    10081 tcacgccgtc gtcggcagca acaaccagga ctacgatgtc cgttgcctgc gcaccacgtg
    10141 cacgcattga agtaaacgcg gcgtgccccg gggtgtccag gaaggtgatc atgccgtttt
    10201 cagtttcaac gtggtatgca ccaatgtgct gggtaatgcc gcccgcttcg ccagaggcaa
    10261 ctttcgttga acgaatgtag tccagcagag aggttttacc gtggtcaacg tgacccatga
    10321 tggtcacaac cggcgcgcgc ggttcagccg cagcacccgt gtcacggtcg ctcattaccg
    10381 cctcttccag ctcgttttca cgacgcagga taactttgtg gcccatctct tcagcaacca
    10441 gctgtgcggt ttcctgatcg ataacctggt tgatggttgc cattgcgccc agtttcatca
    10501 tcgctttgat gacctgagag cctttaaccg ccatcttgtt cgccagttcg ccaacggtga
    10561 tagtttcgcc gatcacaacg tcacggttaa cggcctgagc aggcttctgg aagccttgct
    10621 gcagggaaga acctttacgt tttccgcctt taccgccacg tactgctgcg cgtgcttctt
    10681 cacgatcagc ttttgattca gcgtgtttgt tacctttctt cggacgcgct gctttcgcgt
    10741 tacgaccacg gccacggccg ccttcgactt cacgatcgct ttcgtcttcg gcctggcgag
    10801 catgttgaga agtagtgacg tgataatcgc tggaatcttc agtcggttcc gcgttatcag
    10861 tccatttgtt ttcttccgcc atacgacgtg cttcttcagc aacgcgacgt gcttcttctt
    10921 cgagtttacg acgcgcttct tcttcagctt tacgcttgag ctctgcagct tcctgctcac
    10981 ggcgggcttt ttcagcctgg gcgtttttag tcatatcgtc ttgttgattg ctcactttgt
    11041 ctttttccgc agcttcacgt ttcgcttgtt cagcagcttc acgcttagct tgttctgcgg
    11101 cctcacgttc agctttttgt tgcgcctcgc gtttagccga ttcttctgcc tcacgacggg
    11161 cttgctcttc cgcttcacgc tgcgcttgct cttccgctgc aaggcgttca gcctcttgcg
    11221 gatcgcgttt cacaaaggtg cgtttcttgc ggacttcgat ttgtaccgat ttgctttttc
    11281 caccggtacc aggaatgtta agggtgctgc gtgttttacg ctgcagcgtc aatttgtccg
    11341 ggcctgaatt tttctgattc aggtggtcaa tcaaagtctg tttctcttgt gcagacacag
    11401 agtcgtcagc agacttccgg atacctgcat cagcaaattg ctgtaccagg cgttccacgg
    11461 aggtctgtcg ctctgcggcc agcgttttaa tcgttacatc tgtcatgctg ttccttcctg
    11521 ctacagttta ttacgcttcg tcaccgaacc agcaaatatt acgggcagcc ataatcagtg
    11581 ctccggcttt ttcgtcggtc aacccttcga tatcagccag atcatcaatg ccctgttcgg
    11641 cgagatcttc cagcgtacaa acgccacggg cggccagttt gaatgccaaa tcacgatcta
    11701 ccccttcaag gttcagcaga tcgtcagccg gtttgttatc accgaggctt tcttcctggg
    11761 cctgtgcaat ggtggccagt gcatttttag cacgctcgcg cagtgcttca acggtcggct
    11821 catcaaggcc ttcgatttcc aacagctctt tcatcggcac ataggccagt tcttccagcg
    11881 tcgagaagcc ttcttctacc agaacagtcg cgaagtcttc gtcgatgtcg agatatttgg
    11941 tgaaggtgtc gatcgctgcg tgcgcttccg cctgatgctt agcctgcagg tcgtcaacgg
    12001 tcatcacgtt gagttcccaa ccgctcagct gcgaagccag acgcacgttc tgaccgttac
    12061 ggccaatcgc ctgcgccagg ttaccggctt caacggcgat atccatggtg tgtttatctt
    12121 catccaccac gatagaagca acgtctgccg gtgccattgc gttaatcaca aactgcgccg
    12181 ggttatcatc ccacaggacg atatcgatac gctcgccgcc cagttcagta gaaaccgcct
    12241 gaacacgcgc gccacgcata cctacacagg cacctaccgg atcgatacgt ttatcgttgg
    12301 ttttcaccgc gattttcgca cgagaacccg gatcgcgagc cgctgcttta atttcaatca
    12361 cttcttcgcc gatttctggc acttcaatac ggaacagttc gatcagcatt tccggcttgg
    12421 aacgagtgac gaacagttgc gcgccacgcg cttccgggcg aacggaatag agcacgccac
    12481 gaacgcggtc gccagggcgg aagttttcac gcggcagcat atcttcgcgc aggatcacgg
    12541 cttcagcatt gttgcccaga tccagagaga tgttgtcgcg gtttactttt ttcaccacgc
    12601 cggtgatgat ttcaccttcg tgttcacgga actgatcaac caccatcgca cgttcggctt
    12661 cacgcacttt ctgcacgata acctgttttg ccgtctgggt agtgatacgg tcaaaggtaa
    12721 cagactcaat ctgatcttca acgtaatcgc ccaggttcag gctttcatct tcataacgtg
    12781 cggcttcaag ggtgatttcc ttggtcggct gggtgacttc atcaacaact aaccagcgac
    12841 ggaaggtgtc aaaatcaccg cttttgcgat cgatctgtac gcggacgtcg atctcttgtt
    12901 catatttttt ctttgttgct gtcgccagcg cgctttccaa tgcttcgaaa atcttctcgc
    12961 gaggtagcgc cttttcattg gatacggctt caactacagc caaaatttct ttgttcatcg
    13021 cgggcttttc acctcatcca gactattaaa agtggggaac caggttcgcc ttctggatat
    13081 tactcagcgc gaacacttca tctttacctt cgacggtaac tgtgatcatt tcaccgtcta
    13141 ccgctttgat aacgccctgc catttacgac ggttttgtac cgccatacgg agaaccagag
    13201 tcacctcttc tccgacaaaa cgggcgtagt gttcagccgt gaacagtggg cgatcgagac
    13261 ccggtgagga gacttccagg ttataagcaa cggtgatggg atcttcaaca tccagcacag
    13321 cacttacctg gtggctcaca tcagcacaat catcaacatt gatgccatct tcactatcaa
    13381 tatagatgcg cagtgtggat gtgcgaccgc gaataaattc gatgccaacc agttcaaaac
    13441 ccagggcctc aactggcgca gtaatcatct ctgttaattt ttgctctaat gtggacaagc
    13501 ccacccccaa gacataaaaa aagggcctaa agcccagtta ttctgtagtc agataacaaa
    13561 aaaccccgat aaatcggggc tttatataac tgaaccctat aaccgcaact gcggtctgga
    13621 gcactttcca gaaggatttt ttcaaatccc actacgaagg ccgaagtctt cacagtatat
    13681 ttgaaaaagg actctaaggg aaagtggttg cgggggccgg atttgaaccg acgaccttcg
    13741 ggttatgagc ccgacgagct accaggctgc tccaccccgc gcctgaaaca tggcaaattc
    13801 tactcgtttt gggtaaaaaa tgcaaatact gctgggattt ggtgtaccga gacgggacgt
    13861 aaaatctgca ggcattatag tgatccacgc cacattttgt caacgtttat tgctaatcat
    13921 gtgaatgaat atccagttca ctttcatttg ttgaatactt ttgccttctc ctgctccccc
    13981 ttaagcgcat tattttacaa aaaacacact aaactcttcc tgtctccgat aaaagatgat
    14041 taaatgaaaa ctcatttatt ttgcataaaa attcagtgag agcggaaatc caggctcatc
    14101 atcagttaat taagcagggt gttattttat gacgacgatt ctcaagcatc tcccggtagg
    14161 tcaacgtatt ggtatcgctt tttccggcgg tctggacacc agtgccgcac tgctgtggat
    14221 gcgacaaaag ggagcggttc cttatgcata tactgcaaac ctgggccagc cagacgaaga
    14281 ggattatgat gcgatccctc gtcgtgccat ggaatacggc gcggagaacg cacgtctgat
    14341 cgactgccgc aaacaactgg tggccgaagg tattgccgct attcagtgtg gcgcatttca
    14401 taacaccacc ggcggcctga cctatttcaa cacgacgccg ctgggccgcg ccgtgactgg
    14461 taccatgctg gttgctgcga tgaaagaaga tggcgtgaat atctggggtg acggtagcac
    14521 ctataaagga aacgatatcg aacgtttcta tcgttatggt ctgctgacca atgctgaact
    14581 gcagatttac aaaccgtggc ttgatactga ctttattgat gaactgggcg gccgtcatga
    14641 gatgtctgaa tttatgattg cctgcggttt cgactacaaa atgtctgtcg aaaaagccta
    14701 ctccacagac tccaacatgc ttggtgcaac gcacgaagcg aaggatctgg aatacctcaa
    14761 ctccagcgtc aaaatcgtca acccaattat gggcgtgaaa ttctgggatg agagcgtgaa
    14821 gatcccggca gaagaagtca cagtacgctt tgagcaaggt catccggtag cgctgaacgg
    14881 taaaaccttt agcgacgacg tagaaatgat gctggaagct aaccgcatcg gcggtcgtca
    14941 cggcctgggc atgagcgacc agattgaaaa ccgtatcatc gaagcgaaaa gccgtggtat
    15001 ttacgaggct ccggggatgg cactgctaca tatcgcttat gaacgtctgt tgaccggtat
    15061 tcacaacgaa gacaccattg agcagtatca tgcacatggt cgtcagttgg gccgtctgct
    15121 gtaccagggg cgttggtttg actcccaggc gctgatgctg cgtgactctc tgcaacgctg
    15181 ggttgccagc cagatcactg gtgaagttac cctggagctg cgccgtggga acgattattc
    15241 aatcctgaat accgtctcag agaacctgac ctacaagcca gagcgtctga cgatggaaaa
    15301 aggcgactcg gtgttctcgc cagatgatcg tattggtcaa ttgaccatgc gtaatctgga
    15361 tatcactgat acccgagaga aactttttgg ttatgccaaa actggcctgc tctcctcctc
    15421 tgccacttca ggcgtgccgc aggtggagaa tatggaaaac aaaggccagt aattcgacat
    15481 caaccctgcc cttcagaggt ggggttacct tgcttatcct ctgtaaactc ctttctgagc
    15541 atcacataat cgaaaacatc atggtttgca tccacaaccc gtgagtctcc tttatagtgt
    15601 gcaatcactt cctcaagcgt ttgcggctgt tccggctttg ttacccccat ccacgcatta
    15661 ataaggtaat tattgtaagc tgtcgaaaag atgttgtttt ccgttgtgcg atccacgcca
    15721 tccccaagaa cggggctata ccagataaac atcgggacat gatatgcctg ctggctagcc
    15781 tccctgcctc catgaaaata gacgttcttc ttcgtagggt cacgttccag gccgtggtcg
    15841 gcaaaataca tgaccgaggc gcggcgatct tttaataatt caaaaacctg acctagcaaa
    15901 ctatctgtgt aatgaatgga gttgtcatag caggcatcct gatcgtcctg cggttgaaac
    15961 acggcgctgg attgcggata ggcgctacaa gccggttcat ggcttccatt taaatgaaga
    16021 acaatcagtt tcttttgctg cgtattttgc tgtaatgctt gcgataaatg cggcaacaac
    16081 aattcatcaa atcctctgac ataaactgtt tccatggcgc gcatggcgat actggtaact
    16141 gctgtaccat tctgccgaaa agcggattgc gagcttagcc agaaagtctg aaatcctgct
    16201 tgattagcca tattaataat gttgtcgggg taattatgaa tgtcatgact caaaacagaa
    16261 tcagcagtta aagaaagggg aaccgacagc gcagtgtaag gtgcgccgct tattgcttga
    16321 ttaaacagtt tgatctgttt tctttgtgct tcaacttgcg gtgtcgtaga gcgtgtatat
    16381 ccatacaaag acatattgtc gacacgtaca gactccccca caatcaacac gtaggtatca
    16441 atacctgtat ccctgactga taattgaaaa tacggcaccg tgtttgcaat tgagagtaat
    16501 ctttgatgct ctttcgctgc taaagcaaaa tagttgagat taaaaaacgg cgtataggta
    16561 gcaaatcgcg acgctagtat atatggactg aacgcttttt tattttttgc atctttataa
    16621 gcaaattgac aagcggaaaa taaactgccc gaaatgacaa tcagcaataa tattcctgtc
    16681 actttttttg tcggcaagga aacatcatat tttattatta ctgccaaaaa aagaagggat
    16741 aaaaaagcaa aagcacatag ataagggata tacatcccca gcattttgac aacttcatcc
    16801 ggatcactct ggagcacact aatcgcaaat ccatcattga aagttgtacc aaaggtacac
    16861 catgaataga ggctaatact catgtctgcc gcagtcagta acacaaatgg tgcggcaaca
    16921 agcaggcgaa gcggaaggga tgatatacgt tttacaacca ggatggtcag gacgaagaac
    16981 agcaatcgct gaaccatatg cgcgccggaa gaggcgacta agttcgtaat accaaaaaca
    17041 ataacacaaa gatacaacaa ccaatgagat ttaaaacttc tagcaaattt gttgaatact
    17101 gtcatccaga aatccaagtt cacaaccaat ataaacaatt atcaacaatg ttcaatttta
    17161 tatcagacat gtttttcaac tctgatccat atcagaccga aacactgtta gttttttctt
    17221 tttaaatgat gcggccattg cgttctcagt aattaaataa cattatcaat gcgtctctaa
    17281 acattacgca gaacgtagcc atcagtagtt atactgacag gagcaggatg gtttatcgag
    17341 aagtaaacat atccgtattc gtaccggaac tggagttgac acaataaagt gccaattatg
    17401 tcagcagaag ggaaaagttt ataactaagg cgtaccggca ccatcgtttc aaggtaccag
    17461 ctacgagtaa agcaactgga cgagatacag atacctgaca accattcctc agaccaggac
    17521 caaaacgaaa aaagacgctt ttcagcgtct cttttctgga atttggtacc gaggacggga
    17581 cttgaacccg taagccctat tgggcactac cacctcaagg tagcgtgtct accaattcca
    17641 ccacctcggc acggatacta ctttttagtt cgggatatcg ctggtcggct tagccggagc
    17701 agctggttga gtttgttcgg ttttcaccgg tgcactcaga ttttcccatt cgctaccttt
    17761 attggttttg ttgctattga tgttacccag caccagactg atgatgaaga ataacgttgc
    17821 cagcagcgcc gtcatgcggg tcatgaagtt accagaacca cttgaaccaa acagcgtagc
    17881 ggaagcgcct gctccgaagg aggctcccat atcagcgcct ttaccttgct gcagcatgat
    17941 cagaccaaca aggccaattg ccacaataag gaaaactact aaaagagctt cgtacataat
    18001 caacctgttc cttgcggagt tgccgcgtac caatgcttca accaataaag cgggagtttt
    18061 taatctttcc cactgaagcg ggtgtgaata ctaaccaaag cgaatgacct tcgcaagggc
    18121 aattttatcg cattgtatca actgcggaaa aaaacagcaa aaccgatgtg ttcgctgaga
    18181 aaaaaggcga caatcgccgc ctttttagcc agttatctaa cgctttaaac ggcttttact
    18241 gcatcggcga tgcggtgtgc aaattcagtc acctgcgctt cgtcttcgcc ttccaccatc
    18301 acgcgaatta acggttcggt gccggattta cgcagcaaca cgcgtccacg gttgcccagc
    18361 gcagcttcaa cctctgcggt cacggcttta actgactcat gctcaagtgg atcgccgcta
    18421 cctgcggtgt aacgtacgtt aaccagaatc tgcgggaaca ttttcatgcc gctgcaaagg
    18481 tcgtgcaggc tcatatggtt acgtgccatc gccgccagca cctgcaagcc agcaacgatg
    18541 ccgtcaccgg tagtagtttt atccagtagg atcacatgac cggaattctc tgcaccgata
    18601 cgccagcctt tctcctgcat tttttccagt acgtagcggt cacccacttt cgcgcgcgca
    18661 aatggaattc ctaactgttt cagcgccagt tcaagcccca tgttgctcat caatgtaccc
    18721 acagcgccac cacgcagctg gccctgacga agaccttcac gcgcgatgat atacatgatc
    18781 tgatcgccat cgactttatt gccttcatgg tcgaccataa tcacgcgatc gccatcgccg
    18841 tcgaaggcaa taccgagatc cgctttttca gccagcacac gagcctggag cgcgcgaacg
    18901 tcggtagccc ccacttcggc attgatgttt acaccgtttg gctcacaacc gatagcgata
    18961 acgttcgccc ccagttcgcg cagcacgttc ggcgcgatgt gataagtcgc accgtttgca
    19021 caatccacca caatcttcag ttcactgagg ctaagttcgt tcgggaacgt ggctttgcaa
    19081 aactcgatat agcgacccgc ggcatcaacg atacggctgg ctttacccag ttctgccgaa
    19141 tcaacgcagc tgatctcctt ttccatttcc gcttcgatgg cctcttctac cgcatccggc
    19201 agtttggtgc cgtcgataga gaagaattta atcccattat cgtagaacgg gttatgcgat
    19261 gcagatatca caattccggc ctctgcgcgg aaggtacgcg tcagataagc cacggccggt
    19321 gttggcatcg ggccagtgaa gagtgcggaa aggcccgctg ccgccagacc cgcttccagt
    19381 gctgactcca gcatatagcc agaaatacgc gtgtctttac caataataat cttacgggag
    19441 ccgtggcgcg ccagcacttt acccgcggcc caacccagct taagcacaaa atcaggtgtg
    19501 atcggcgcat cccctacacg accacgaatc ccatcggtac cgaaatattt acgattactc
    19561 atagcgtttg ttttcctttg cagacagagt ggcttccacc acccgcatcg cttctacggt
    19621 ttctttgacg tcatgaacac gaatgatgtg cgctccttgc attgcggcaa tgaccgcaca
    19681 ggccagacta ccgctcaggc gctcggacgg ccccacgttc agcagctgcc caatcatcga
    19741 ttttcgtgac atacccacca acagcggcag gttgaaatgg tgaaattcag ccaggcgcgc
    19801 cagtaatgaa tagttatggg agagattttt accgaaaccg aatccggggt cgagcaacaa
    19861 tttctctttt gcgatacccg cctgctcgca acgtgctatt tgctcaataa agtagcgatt
    19921 cacttctgca aagacatcgt catacttcgg agcttcctgc atggtttttg gatttccctg
    19981 catatgcatc agacaaaccg gtaaaccggt ttctgcagcc gcctccagag cgccaggttc
    20041 ggaaagggag cggatatcat taataatgtg agcgccaact ttcgctgact cacggatgac
    20101 ttctggtttg gatgtatcga ccgagatcca gacttcgaag cgttgagcaa ttgcctcaac
    20161 cacaggaata acacgttgca actcttcttc aacgctaact tccgccgccc ctgggcgcgt
    20221 ggactcgcca ccaacgtcaa tgatcgtcgc gccagcattg atcatcagat tcgcatgttt
    20281 caccgcatct atcagcgagt tatgcgtgcc accatccgaa aaggaatcag gcgtgacgtt
    20341 gaggatcccc attacgtgag gatggctaag gtccagtgaa gtaccctggg caaagagttt
    20401 catgatgtta tccctggtat gaattgataa gaaaaaaccc cggagcacgc cccggggttt
    20461 tcggtacaaa tacagtcatc tgatgcggga acttacttgt cgcctaactg ctctgacatg
    20521 gtgttacccg ggttcggcgt acgcggttca tcaaccggac gaggagcctt tggactacca
    20581 ttgtcgccag aattgttaga agcgcctggt tcttcccagc ccgctggcgg acgtacatcg
    20641 cgacgtgcca tcaggtcatc aatctgcggt gcgtcgatag tctcatattt catgagagca
    20701 tctttcatcg catgcagaat atccatattg tcggtcagaa gctgacgcgc acgattatag
    20761 ttacgctcaa tcagtgcttt cacttcctgg tcgatgatac gtgcagtttc atcggacata
    20821 tgtttcgctt tcgctacgct acggccgagg aatacttcac cttcttcttc cgcgtacagc
    20881 agtggaccca atttctcaga gaagccccac tgggtcacca tgttacgtgc cagattggtc
    20941 gcaactttaa tatcgttgga cgcaccggta gaaacatgtt ccggcccata gatgatctct
    21001 tctgccagac gaccaccgta cagcgtagaa atctggcttt ccagtttctg acggctggcg
    21061 ctgattgcgt cgccctcagg caagaagaaa gtcacaccca gcgcacgacc gcgtgggata
    21121 atcgtcactt tgtgcaccgg atcgtgttcc ggcaccaggc gaccgataat cgcatgaccc
    21181 gcttcgtggt aagccgttga ttctttctgc gcttccgtca tcaccatgga gcgacgttcc
    21241 gcacccatca tgattttgtc tttcgctttc tcgaactcaa ccatcgacac aacgcgtttg
    21301 ttgccacgag cagcgaacag tgccgcttcg ttcaccaggt tcgccaggtc agcaccggag
    21361 aaaccaggag taccacgggc aatgattgcc gcgtcgatat cgggggccaa tggtacgcga
    21421 cgcatgtgaa ctttcaggat ctgctcacga ccgcgaacat ctggcaagcc gaccacaacc
    21481 tgacggtcga aacggccagg acgcagcagg gccgggtcga gaacgtccgg acggttagtc
    21541 gcggcgataa cgatgatacc ttcgttacct tcgaagccat ccatctcaac cagcatctgg
    21601 ttcagagtct gttcacgttc atcgtgacca ccgcccagac cagcgccacg ctggcggcct
    21661 acggcgtcga tttcatcgat aaagatgatg cacggtgccg ctttcttcgc ctgttcgaac
    21721 atgtcacgaa cacgggatgc acccacaccg acgaacattt ctacgaagtc agaaccggag
    21781 atagtaaaga acggaacttt cgcttcgcct gcaatcgctt tcgccagcaa cgttttaccg
    21841 gtacccggag gaccgaccat caggacgcct ttcgggatct taccgccgag tttctggaag
    21901 cggctcggct cgcgcagata ctctaccagt tcagcaactt cttcttttgc ttcgtcgcag
    21961 cccgcaacgt cagcaaaggt cgttttgatc tgatcttccg tcagcatgcg cgctttgctc
    22021 ttaccaaacg acatggcacc tttgccaccg ccgccctgca tttgacgcat gaagaagatc
    22081 cagacaccaa tcagcaacag catcgggaac caggagatga agatagaagc cagcaggctt
    22141 ggttcttcag gcggttcacc gacaaccttg acgttcttgg tcaacaggtt atccagtaat
    22201 ttcggatcct gaaccggaat gtaagtggta taacggttac tatctttctt ggtaacgttg
    22261 atttcacgtc cgttgatacg cgcttcacga acctggtcgt tattgacctc ttgtaggaag
    22321 gtagagtaat ccaccttacg gccattagac tcgctgggcc caaagctctg gaatactgac
    22381 atcagcacaa cggcaatgac cagccagagt attaggtttt tcgccatgtc actcaaggga
    22441 ttaacctctt attacaactg tgttaaaaac agcgtcagga tactctatat ccagcatctt
    22501 tcaaactttc gtctgaaatc tcccggttag ggtttacgcc cggtcgctac aatatacact
    22561 tcccgcgaac gtgcacgaga agagtccggc ttacgaactt tgaccttcgt aaacagggag
    22621 cgaatttccc ttagatactc atcgaaacct tcgccctgga acaccttcac tacaaaactg
    22681 ccacctggcg ctaatacatc acgacacatt tctagcgcca gttccaccag atacatggca
    22741 cgggggatat ccaccgccgg tgttccgctc atgtttggtg ccatatcgga catgacaacc
    22801 tggactttgc tgtcgccaac gcgctccagc agtgctttca tcaccagttc atcacgaaaa
    22861 tcgccctgaa gaaagtccac accaacgata ggatccatag gtaaaagatc gcaagcgatg
    22921 atgcggcctt tgccgccaat ttgggtgacc acatattgtg accaaccacc cggagcagca
    22981 ccaaggtcga caaccgtcat tcccggttta aagagtttgt cactttgctg tatttcatca
    23041 agtttaaacc aggcacggga acgtaacccc tttttctgtg cctgttgaac atatttatcg
    23101 ctaaagtgtt cctgaagcca gcggctggag ctggcagaac gcttcttacc tgtcatttaa
    23161 ctttcccatg gggataactc atcgtaacca attgcgtaaa tttttacgcg cctatttggt
    23221 gatatatggg agatggcggt agaatgaccc gttttcaatc ccaacgtaag caaaaaatac
    23281 gatgaatctg agtactaaac aaaaacagca cctgaaaggt ctggcacatc cgctcaagcc
    23341 agttgttctg cttggcagta atggtttgac cgaaggggtg ctggccgaga ttgaacaagc
    23401 gttagagcac catgaactca tcaaggtgaa aatcgccacc gaagatcgcg aaactaaaac
    23461 cttgatcgtg gaagctatcg tgcgcgaaac cggcgcctgt aatgtacagg tcatcggtaa
    23521 aacgctggtg ctttatcgcc caactaaaga acgtaaaatc tcgctgccac gctaagatta
    23581 tcctaaagtt acacacattt gctgtgtaaa acgaggggtt ttccgcaggc aggagagcaa
    23641 aatgccacgc tctgttcgtt gataaaaggc cgcatagcgg cctttttcct ttctttacaa
    23701 tacatcaaca tcttgagtat tgggtaattc ttacaggtat tccaccttaa ttacttcaaa
    23761 ttctacttcg ccgcccggcg ttttgatgac cacaacatca tcttcttctt tgccgatcag
    23821 gccacgagca ataggcgagt ttacagaaat caggttttgt ttaaagtcag cttcgtcatc
    23881 gccaacgatg cgataagtct gttcttcgtc agaatccaga ttcagcaccg ttacggtagc
    23941 accaaaaata acgcgcccat tgttgggcat tttggtgaca tcaatcacct gcgcgttcga
    24001 cagcttggct tcgatgtctt taatacggcc ttcgcagaaa ccctgctgtt cacgagctgc
    24061 gtggtattcg gcgttttctt tcaggtcgcc atgctcacgc gcttccgcga tagcagcaat
    24121 gatttcagga cggcgcacag atttcagaaa atccagctct tcgcgtaatt tttcagcgcc
    24181 gcgtaaggtc atcggaatag cttgcatttg ttatacctct tgaatattcc tgatggggca
    24241 agtcttcacc caccccggct gttcggcctg cccggcataa ctcctcaccg ggaccagaag
    24301 caaaaaaata ccgacccggg tacaagtccc aggtcagcta caattcacat tttgatagtc
    24361 attttaccct gaagttcccg aagggtcatc gtttacttta tagggcgttg cgccgtagta
    24421 tgacggctcg attccaggtt gttagcgcga gattatgcga ttttccagat ttatcatcgg
    24481 attgaccagc tgtatagcgt tcagtgttca ggccgcgaat gttgatgagt acgttactca
    24541 actccccgct ggtgccaacc ttgccctgat ggtgcaaaaa gtcggcgcgt cggcccccgc
    24601 tattgattac cacagtcagc agatggcgct gcccgccagt acgcagaaag tgattactgc
    24661 gctggcggcg ttgattcaac tcggccccga ttttcgtttc accacgacgc ttgaaaccaa
    24721 aggcaatgtg gaaaacggcg tacttaaggg tgacttagtg gcgcgatttg gtgccgatcc
    24781 gacgttaaaa cgtcaggata ttcgcaatat ggtcgcgact ttgaaaaaat ctggcgtcaa
    24841 ccaaatcgat ggcaatgtgt tgatagatac ctccattttc gccagccacg ataaagcccc
    24901 cggctggcca tggaatgaca tgacacaatg ctttagcgct ccgcctgccg ctgccatagt
    24961 tgaccgcaac tgtttctccg tctcgctcta cagtgcccca aaacctggtg atatggcttt
    25021 tatacgcgtg gcatcttatt accccgttac gatgttcagc caggtacgca ccctcccccg
    25081 aggttctgcc gaagcgcaat actgcgaact ggatgtcgta ccaggcgacc tgaaccgctt
    25141 tacgctgacg ggatgcctgc cacaacgttc tgagccgctc ccgttggctt ttgccgtgca
    25201 ggatggagcc agctatgccg gggcaattct gaaagatgag ttaaaacagg caggtatcac
    25261 ctggagcgga acactgctgc gccagactca ggttaacgaa cctggaacgg tagttgccag
    25321 taaacagtcg gccccgttgc acgatctgct taagattatg ctgaaaaagt cggacaacat
    25381 gatcgccgat acggttttcc gcatgatagg ccatgcgcgc ttcaatgtgc ctggaacatg
    25441 gcgggccggg tcggacgccg tgcgtcagat cctgcgccag caagccggtg tcgatattgg
    25501 aaacaccatt attgccgatg gttcagggct ttcgcggcat aacctgattg cccccgccac
    25561 catgatgcag gtgctgcaat acattgccca acacgacaat gaacttaact ttatctccat
    25621 gctgccgctt gcgggctatg acggctcttt gcagtaccgt gcaggtctgc atcaggcggg
    25681 cgtggatgga aaagtctcag cgaaaaccgg ttcgttgcag ggggtatata acctggcggg
    25741 attcattacc acagcgagcg ggcaacgaat ggcgtttgta caatatcttt ctggctatgc
    25801 agtagaaccg gcggatcagc gtaatcgccg tattccgtta gtgcgttttg aaagccgttt
    25861 gtataaagat atttatcaga acaattagtc aaaaagaaac cccggcacat ggccggggtt
    25921 ttgctgatta acgcttgtaa atgaactcaa cgccttcttc gtcgtcttcg tcccagtcat
    25981 catcccagtc ctcatcatcc tcttcagcaa tctcttcaag ctgctggcga tgataatcat
    26041 cccacatgaa ttcgactttc tctggctgtt tcgcttcttc agcctgcacg accgggtttt
    26101 caatgataaa ggtcatcaca tcccagcaga gatctttcac gcccagtcca ctcgccgcag
    26161 agatcagata atatttatct tcccagccca gcgcttcagc aatcgctttc gctttctctt
    26221 cagcttctgc cttatccagc agatcgatct tattgaacac taaccaacgt ggtttcgccg
    26281 ccagatcctg gctgtatttt tccagctcgc tgataataat acgcgcgttt tcaaccggat
    26341 cggtgccgtc aatcggatcg atatcgatga ggtgcaacag gacgcggcaa cgttccaggt
    26401 gcttcaggaa gcgaatgccc agacctgcgc cttccgcagc gccttcaatc agtcctggaa
    26461 tatcggcaac aacgaagctc ttttcgttgt ccattcgtac cacacccaga cttggcacca
    26521 gagtggtaaa cggataatcc gccactttcg gtttagccgc cgataccgca cgaataaagg
    26581 tcgatttacc cgcgtttggc atccccaaca taccgacgtc agccagcagc atcagctcca
    26641 gcagcagctc acgcttatcg cccggcgtac cgttagtttt ctgccgtggt gtacggttaa
    26701 ctgacgattt gaaacgggta ttgcccagac cgtgccagcc gcccttagca accagcagac
    26761 gctgaccgtg tttggtcata tcgcccatgg tttcaccagt accctggtcg attacacgcg
    26821 tacctaccgg cactttaatt gtgacgtctt taccgcgctt accggtacag tcgcggcttg
    26881 cgccattctg accgcgctct gcacggaaag atttttcaaa acgataatcg ataagcgtgt
    26941 tcaggttctc gtcggcttcc atccatacgt caccaccatc accgccgtcg ccgccatccg
    27001 ggccgccttt cggaatatac ttttcgcggc ggaagctcac gcaaccatta ccgccatcac
    27061 ctgcaacgac cagaatcgat gcttcatcaa caaacttcat tttattctcc gtaaatcatt
    27121 cgcctgcgcg gggttgcgat accaccgttg tatgcttacg taatccgccc caaatacgat
    27181 gaccaatggc ggaatacatc gcgcccgcaa ccacgacaaa cgcaccgaga taacctaaaa
    27241 ggtttaacat cggtctggcg aagaaatcgg gccaggccag tgataaaaga tctgaaaaaa
    27301 acagcgtaaa cagtggggtg agcgtgatga tcgcgctcac ctgcgctgcc tgccagcgag
    27361 ccatcgcttc cgccagggcg ccatatccta ccaaggtatt cagtccgcaa aaaattaaac
    27421 atgcgagctg ccagtggcta agctgcgcta tcactccagg ctttgccaga gggaagagcg
    27481 caattgtaca taaagtgtac agtaaaaaca ggatctgcgg tgaggccagc cgacgcaata
    27541 aaaccttttg cgccacgcca taactcaccc aaaccgtcgc cgcaccgacc ccaaagataa
    27601 ctccccaggt gtaatcggtg agctttgtaa atatctcgac cagactggtg ttaaaaaaca
    27661 tcaccaggcc gctcaggagc atcaatgccc ctacaacctg agtgctgcgc attttctctt
    27721 tcaggataaa tacgctggca accatcatgc caactggcga gagttgccca atcacctgcg
    27781 aagcggtcgg actcaggtat tgcaaggatg agctgaacag gatgaagttc ccaaacagcc
    27841 cggcggtcgc cactgccaac aaaatcaacc agcgtggctt acgaaacacg cgtaatggcg
    27901 gcaacctctt cttcaccgca agaatggcac caaggccaat actcgccatc aagaaacggt
    27961 aaaacacgat tgtcggaggt tccatcacct ccagcacctg cttcattgcg attggcaacg
    28021 ccccccagca aattgctgtg gtgagcgcca aaagaatgcc aatgcctgcc tgctgcttca
    28081 taccgtattc cctgcaaagc gcatttgcgg attaacgtcg caccatgcgc atttttaccg
    28141 gttatcgaat gtaaaaagcc ccgcaacgtg ttgcggggct ttcatccgtt accgggacgc
    28201 gaaaaactta ttcagcttcg atgctgataa atttacggtt tttcgggcct ttaacttcga
    28261 atttcacttt accgtctgct ttagcaaaca gagtgtggtc acgaccgcaa cctacgttag
    28321 cgccagcgtg gaatttggta ccacgttgac gaacgatgat gctacccgcc agaacggatt
    28381 cgccaccgaa acgcttaacg cccaggcgtt tagcttctga atcgcgaccg ttacgtgtgg
    28441 agccgccagc ctttttatgt gccatttgaa atctctcctc aggtcttagg cgctgatgcc
    28501 agtaattttc acatcagtga accactgacg atggccctgc tgcttacgat agtgtttacg
    28561 acgacgaaac ttaacgattt taactttctc gccacgaccg tgagcaacaa cttcagcttt
    28621 gattacgccg ccatcaacga aaggaacgcc gattttgact tcttcaccgt ttgcgatcat
    28681 cagcacttca gcgaactcaa cagtttcgcc agttgcgatg tccagctttt ccaggcgaac
    28741 ggtctgacct tcgcttactc ggtgttgttt accaccactt tggaaaaccg cgtacatata
    28801 aaactccgct tccgcgcaca ccttttcaat gattcagagt gcgctataaa tattcacaat
    28861 agggcgcgaa tattacgcaa aacgcacgcc tttgacaagt gctacagtca atacacgaag
    28921 aaaaaaaaca caacttgtac ggtaacgttt atctgtgcca ttttttcagt acaatcactc
    28981 tatattccta accataaacc ctaagttgcc tttgttcaca gtaaggtaat cggggcgaaa
    29041 agcccggctt ttgcgatgaa tttagaaaaa atcaatgagt taaccgcgca agatatggcg
    29101 ggtgttaatg cggcaatcct tgagcagctt aattccgacg tccagctgat caatcagtta
    29161 ggctattaca tcgtcagcgg cggcggtaaa cgtattcgtc cgatgattgc tgtactggct
    29221 gcacgagctg ttggctatga gggaaatgcg catgtcacca ttgctgccct gatcgagttt
    29281 atccacacgg cgactctgct gcacgacgac gttgtggatg aatcagatat gcgcaggggt
    29341 aaagctaccg ccaacgctgc atttggcaat gccgccagcg tgctggtagg cgattttatt
    29401 tatacccgcg cgttccagat gatgaccagc ctcggttcgc tcaaagtgct ggaagtcatg
    29461 tcagaagccg taaacgtcat cgcagaaggt gaagttctgc aactgatgaa cgttaacgat
    29521 ccggacatca ctgaagaaaa ctacatgcgc gttatctata gcaaaaccgc gcgtctgttt
    29581 gaggctgccg cgcagtgttc cgggattctg gctggctgta cgccggaaga ggagaaaggc
    29641 ctgcaggatt atgggcgcta tctcggcact gctttccagt tgatcgacga tttactcgat
    29701 tacaatgccg atggcgaaca gttaggtaaa aatgtcggcg acgatctgaa cgaaggtaaa
    29761 ccgacgctgc cgctgctgca tgcgatgcat catggcacac cagaacaggc acagatgatc
    29821 cgtaccgcca tcgaacaggg taacggtcgc catcttctgg aaccggttct ggaagcaatg
    29881 aacgcttgtg gatctcttga atggacgcgt cagcgtgccg aggaagaagc agacaaagcc
    29941 atcgcagcat tacaggtgct cccggacacc ccttggcgag aagcactcat cggcctcgcg
    30001 cacatcgctg ttcaacgcga tcgttaatcc cctcccttca tcccgcgcag tgcgcgggat
    30061 gattccagta aattccataa aaacactaat tcagcgctat aacacctgaa aaaaagggcg
    30121 atgaatcttt atatattctg aatattcaca ctctttacag gaacttttta gagcaatagg
    30181 ccatcaggag tatagtgatg cccgacagaa gaagtgttct gaatgaaagc gactaactta
    30241 aggagtgagg aaagatggaa agtaatttca ttgactggca tcccgctgac atcattgcgg
    30301 gtttgcgcaa gaagggaacg tcaatggcgg cggagtctcg cagaaatggt ttgagttcct
    30361 caacgctggc aaacgcatta tcgcgcccat ggccgaaagg agagatgatt attgcgaaag
    30421 ccctgggaac tgacccctgg gttatctggc catcacgcta ccatgatccg cagacccatg
    30481 agtttatcga cagaacgcag ttgatgcgta gctacactaa accgaaaaaa tgagtggtct
    30541 ggcggtagcc ccgcgaacgg ggctgccagc tctcagacga ttactcgcct ttcacacgct
    30601 caatatttgc acctaaagcg cgcagtttgt cttcaatgcg ttcgtagcca cgatcgatgt
    30661 gataaatacg atcaaccacc gtcgtccctt ccgcaataca gccagccagc accaggcttg
    30721 ctgatgcacg cagatcggtt gccataacct gtgcgccaga aagtttttca acaccgtgac
    30781 aaataacggt attgctttcg atttcggcat gcgcgcccat acggctaagc tccggcacat
    30841 gcataaagcg gttttcaaag accgtttcgg tgatgaatcc ggtcccttct gccaccaggt
    30901 tcaacagcgt gaactgggcc tgcatatcgg tcgggaatgc cggatgcggc gcggtacgta
    30961 cgttaacagc cttcggacgt ttgccatgca tatccaggct aatccagtct tcgccgactt
    31021 cgatgtccgc tccagcgtca cgcagtttcg ccagcacggc gtcgagagta tctggctgcg
    31081 cgttacggca gataattttg ccgcgagaaa tcgccgccgc caccaggaaa gtaccggttt
    31141 cgatacgatc cggtagcacg cgatagacac cgccgcctaa acgttccaca ccttcgatga
    31201 cgatacgatc ggtgccctga ccgctaattt tcgcacccag cgtaatcagg aagttcgcgg
    31261 tatcgacgat ttccggttca cgcgctgcgt tttcaataat cgtggtacct tccgccaggg
    31321 ttgcagcaca catgatggtc accgttgcgc caacgctgac tttatccatc acgatatgtg
    31381 cgcctttcag acgaccatcg acggaagctt taacgtaacc ttcttccagt ttgatggtcg
    31441 cgcctaattg ttcgaggcca gaaatgtgta gatcaaccgg acgcgcaccg atcgtacaac
    31501 cgccaggcag tgaaacttgc ccctgaccaa agcgcgctac cagcggcccc agtgcccaga
    31561 tagaagcacg catggtttta accagatcgt aaggtgcgca gaatacatta acgtcgcggg
    31621 catcaatatg cacagaacca ttacgttcta ctttcgcacc cagctggctt agcagcttca
    31681 ttgatgtatc gacgtctttc agttttggga cgttctggat ctctaccggt tcttccgcca
    31741 gtagagcggc aaaaaggata ggcagagcag catttttagc gccggaaatt gtgacttcgc
    31801 cctggagctt cgttggcccc tgaacacgaa atttatccat ttagtttgtt ctcagttaac
    31861 aattcatatc cgctaccggc gaatcgccca tagctcaaaa gccgttcagt ttgcgatcgc
    31921 gcgcccactc cgcaggggta tacgctttga tcgacacagc atgaatgcgg ttatccgcaa
    31981 tatattccat cagcgggcca tagaccgtct gctgtttttt aacccgactc atgccgtcaa
    32041 acaactcacc cacggcaata acctgaaagt ggctgccatc gccggaaacg tggacttcct
    32101 ggagggagag agcgttcatc aacacgctct gaatttcatt attttccatg ggatcttcaa
    32161 tcatcagtta ataaaccagc gaaacatctt agagcaaagt tgcgctggca taaataagca
    32221 aaaagcctcg ctgataaatc agacaaggct cgacttgcag gcaggtttgc cggacaggcg
    32281 gttaacgcca tatccggcct gaaaaaattt aacgaggcag aacatcagca ggcaaattat
    32341 acaatttcgc cagggtatac actttgtcgt ttaccccctg aagcgtcaca ttgttgccct
    32401 gctttttcgc cagatcgata agatggagca gcagtgccag tccccccgta tccacgcggg
    32461 acacacggct aagatcgatg caggtaatcc ccttcaccgc ttcctcacgc atttcccaaa
    32521 gcggtagcaa aacgtcctga tccagctctc cggataacgc cagcgtgtca cccgtctgca
    32581 tccagctcag tgactcgctc attatttttt ctcttccaga gtgattttct gttgagaaat
    32641 cgatttcagt tgcgcagtca ggccgtcgat acctttggta cgcagcagcg ttccccactc
    32701 gttttgtttg gtggtgatca tactgacgcc ttcagcaatc atgtcgtaag cctgccagtt
    32761 gcccgtctgg gagtttttac gccactggaa gtccagacgc accggcgggc ggccattcgg
    32821 atcaataatg gtaacgcgaa tcggcacaat ggttttatcg cccagcggct gttctggcgc
    32881 aatctgatag gtttgaccgt gatacatcgc cagcgcctga ccgtaagcct gcttcaggta
    32941 ctcacggaaa gcggcaaagt aggcttcacg ttgagcaggg gtcgcactct tgtaatactg
    33001 gcccagcacc agcgcaccgg cgtatttcac ctgtacgtat ggcagcagtt cctgatcaac
    33061 aatggtacgc agataatccg ggttggcccg aatttgcggt tgctcattct tcaggcgatc
    33121 gaacgttttc tgcgccgcct cgtccatcag cttataagga ttggtctggt ctgccgcggt
    33181 tgccgcactc agaggtgcaa tcaccagcaa agcgaccatc attaaacgtt taaacatgcg
    33241 tcggttctcc tgaaattatt tcgttgtacc cacaggttca gtggtttcat tattacctgg
    33301 cgcagcagct ggcgcatcgc cactattctt attgtcatcg cctttactac cgtaaaggaa
    33361 ctgaccaatg agatcttcca gcaccatcgc agacttagtg tcctgaattg tatcgccatc
    33421 cttcaggata gcagtcccca gttccgggtc ttcaaaaccg acgtttaatg ccagatattg
    33481 ttcccccagc aggccggaag tacgaatgct cagcgaactg gtatctggaa tgtggttata
    33541 acgttgttca atttccagcg ttacgcgcgg cagataggtt ttcgggtcca gcgtaatatc
    33601 cgccacccga cccacaacaa cgccaccaat actgaccgga gagcgcgctt tcaggccgcc
    33661 aatgttatcg aacgtcgcat aaagcgtgta ggtcggttca gtacgtatgg acgtcacgtt
    33721 cgccgccttc aggcaaacaa acagcgccgc cagcagtgct gctaataaaa agatacccac
    33781 ccaaatttca ttttttttcg tttgcatgaa ctcaattccc aaacatcaat gcggtcagca
    33841 caaaatccag ccccagaaca gccagagacg agtggacaac ggtgcgagtg gttgcccggc
    33901 taatcccggc agacgtcggg atggcgtcgt agccgttaaa caacgaaatc cacgtcaccg
    33961 tgatggcgaa caccacgctc ttaatcagac agttgaccag atccatacgc cagtcgacgg
    34021 cattttgcat tgccgaccag aagaacccgc tatcaatgcc tttccaactg acgccgacca
    34081 gagatccgcc ccagatcccc acggcgacga aaataaccgt caacagtggt aatgaaataa
    34141 ccccagccca gaaacgggga gaaataaccc gacgcagcgg atccaccgcc atcatctcca
    34201 tactggagag ttgctctgta gcgcgcatca ggccgatttc tgcggttagc gccgaaccag
    34261 cacgcccggc aaacaacaac gcggcaacca ccggccccag ttcacgcagt agcgataacg
    34321 ccaccagcat acccagactg gtttccgcac tataagtggt cagaaccaga taaccttgca
    34381 gccccaacac cattccgatg aacacgccag aaaccacaat aatcagcatc gacaggacgc
    34441 cgacattata gagctggcgc accagcagcg gcgcatgttt gcgaaattcc ggtttgccga
    34501 ccagcgcatt gaataacatt aacccggccc gcccgaacgt tctcagggtt ttaatccctt
    34561 tatgtccgag cgacgccagc gcatttaaca gcatgagtgg cttaactccc tggtaaaaga
    34621 tcagcgtgat aatcgccggc aggatagcgg aacggaacag gcccgtcagc tatcccgtcc
    34681 agaaactgac gtacgcgcgg atcaggattc gcctgcaacg cctgggcact gccatgagcg
    34741 acaatttttt tgtccgccag gatccaggcg tgatccgcaa tacttaacac ttccggcaca
    34801 tcgtgagaaa ccaccacaca agtcacgccc agcgcgctgt tcagctcaga aatcagcttc
    34861 accagtacgc ccatggtgat gggatcttgc ccaacaaaag gttcatcaaa catgatgaga
    34921 tccggctcca gcgcaatcgc acgcgccagc gctgcacgcc gcgccatccc accggaaagt
    34981 tcagaaggca ttagtttagc cgctccacgc agccccacgg cctccagctt catcatcacc
    35041 gtactatgca acaatggcgc gggaagttgg gtatgttcgc gcagtggata ggcgacgttg
    35101 tcaaatacgt tcatatcagt gaacaacgcc ccggactgaa ataacatgct catccgtttg
    35161 cgcactgtat acaggcgcga acgagacatc gccggaatat tctcaccatc gaaaaggatc
    35221 tcaccatgat ctggtgcgat ttgcccgcca atcagacgga gtagcgtcgt tttaccgatg
    35281 cccgatggcc ccatgatcgc cgtgatcttc cctcgcggca cggtcaggga aatattatcg
    35341 aagatgcagc gattgccacg cgtaaaactg acatcgcgca tatcgactaa attcgccaca
    35401 gactgctcca taattcaccc ttcgtcttgc gttgattttc taagcatggc gctcaattta
    35461 accttgaacc caacatattt acagaatatt acccgccgtg gttagcgaaa gctggcattt
    35521 gttttacttt ttagccgcat aaagtcaaaa ttaagaatcc gttacggctt tctgaaaatc
    35581 ttcagcggac cggcgagtat acctgaagaa aggacgttag atgcttttag ctacggcact
    35641 gttaattgtt ggtttacttt tggtcgttta cagtgccgac cgcctggttt ttgccgcgtc
    35701 tattctttgc cgaacctttg gcatcccgcc gctgatcatc ggcatgacgg tggtcagtat
    35761 tggtacatcg ttaccagaaa tcatcgtctc gcttgccgcg tctctgcacg aacaacgcga
    35821 tttagccgtt ggtacagccc tcggctcaaa cattatcaat atattgctga tcctcggtct
    35881 ggctgcgctg gttcgtcctt ttaccgtcca ttctgatgtt ctacgccgtg aattaccctt
    35941 aatgttgttg gtcagcgtgg tggccggttc cgtactctat gacggacaac ttagtcgcag
    36001 cgatggtatc tttctcctct ttctggctgt gctatggctg ctgttcattg ttaaacttgc
    36061 acgtcaggct gaacgtcagg ggactgacag cctgaccaga gagcagcttg cagagctgcc
    36121 gcgtgacggc ggattgcccg tcgcgttttt atggctcggc attgcgctta tcatcatgcc
    36181 agtggccacg cggatggtgg ttgataacgc cacggtgctg gcgaattact ttgccatcag
    36241 cgagttgacg atgggtctga cggcaattgc tatcggaacc agcctgccgg aactggcaac
    36301 cgcaatagcg ggggttcgca aaggtgaaaa cgacattgct gtcggaaata tcattggcgc
    36361 aaacattttt aatattgtca tcgtgttggg tttacccgcg ctgataacgc caggagagat
    36421 tgatccactg gcgtacagtc gtgactacag cgtgatgttg ctggtgagca ttatttttgc
    36481 gttgctgtgc tggcggcgct ccccgcaacc gggccgtggt gtaggggtat tattaactgg
    36541 cggatttatc gtatggctgg cgatgttgta ctggttatcg ccaatactcg ttgaataact
    36601 ggaaacgcat tatgtcgcac gtagagttac aaccgggttt tgactttcag caagcaggta
    36661 aagaagtcct ggcgattgaa cgtgaatgcc tggcggagct tgatcaatac atcaatcaga
    36721 atttcacgct tgcttgtgaa aagatgttct ggtgtaaagg gaaagttgtc gtcatgggga
    36781 tggggaaatc ggggcacatc gggcgcaaaa tggcggcaac gtttgccagc accggtacac
    36841 cttcattttt cgtccatcct ggtgaagccg cgcatggtga tttaggcatg gttaccccac
    36901 aggatgtggt gattgctatc tctaactcag gtgaatccag cgaaatcacg gccttaattc
    36961 cagtgcttaa gcgtcttcac gtaccgttaa tctgcatcac cggtcgcccg gagagcagca
    37021 tggcgcgcgc cgcagatgtg catctgtgtg ttaaagtagc gaaagaagcc tgtccgttag
    37081 ggctggcacc gaccagcagc accaccgcca cgctggttat gggcgatgcc ctcgctgtcg
    37141 cgctgttaaa agcacgcggc tttactgctg aagattttgc gctctcacac ccaggcggcg
    37201 cactgggtcg taaacttctg ctgcgcgtaa acgatattat gcatacgggc gatgagatcc
    37261 cgcatgttaa gaaaacggcc agtctgcgtg acgcattgct ggaagttacc cgcaaaaatc
    37321 ttggtatgac tgtcatttgc gatgacaata tgatgattga aggcatcttt accgacggtg
    37381 atttacgccg tgtcttcgat atgggcgtgg atgttcgtca gttaagtatt gccgatgtga
    37441 tgacgccggg gggaatacgt gtgcgccctg gcattctggc cgttgaggca ctgaacttaa
    37501 tgcagtcccg ccatatcacc tccgtgatgg ttgccgatgg cgaccattta ctcggtgtgt
    37561 tacatatgca tgatttactg cgtgcaggcg tagtgtaaag attcaaggat aaacaacaat
    37621 gagcaaagca ggtgcgtcgc ttgcgacctg ttacggccct gtcagcgccg acgttatagc
    37681 aaaagcagag aacattcgtc tgctgatcct cgatgtcgat ggcgtactgt cagatggcct
    37741 gatttatatg ggcaataatg gcgaagagct gaaagcgttc aatgttcgtg acggttatgg
    37801 cattcgttgt gcgctcacct ctgatattga agtcgctatc attaccgggc gaaaggctaa
    37861 actggtagaa gatcgttgtg ccacattggg gatcactcac ttgtatcagg ggcagtcaaa
    37921 taaactgatc gcctttagcg atctgctgga aaaattggcg attgccccgg aaaatgtggc
    37981 ttatgtcggc gatgatctca tcgactggcc ggtaatggaa aaagtgggtt taagcgtcgc
    38041 cgtggccgat gcgcatccac tgttgatccc gcgcgccgat tacgtgacgc gcattgctgg
    38101 cggtcgtggc gcagtgcgcg aagtttgcga cttattactc ctggcgcagg gcaaactgga
    38161 tgaagccaaa gggcaatcga tatgagtaaa gccagacgtt gggttatcat tgtgctatca
    38221 ctggcggttc tggtgatgat cggcattaat atggccgaaa aagacgatac cgcccaggtg
    38281 gtcgtcaaca acaatgatcc cacctataaa agcgagcata cggacacgct cgtctataac
    38341 ccagaagggg cactaagcta tcgattgatt gctcaacacg ttgaatatta ttccgatcag
    38401 gccgtttcgt ggtttacgca gccggtactt accacgtttg ataaggataa aatcccgaca
    38461 tggtccgtaa aagcagataa agccaagctg accaatgacc ggatgctcta tttatatgga
    38521 cacgttgaag tcaacgcact cgtgccggac tctcaacttc gcagaatcac gacggataac
    38581 gcgcagatca atctggtgac gcaggatgtt acctctgaag acctcgtcac gttatacgga
    38641 acaacattta actccagcgg tctgaaaatg cgcggcaact tacgcagcaa gaacgccgag
    38701 ctgattgaaa aggttagaac atcctatgaa attcaaaaca aacaaactca gccttaatct
    38761 tgtgcttgcc agctcacttc tggccgccag cattccggca tttgccgtaa ccggagacac
    38821 tgatcagccg atccacattg aatcggacca gcaatctctt gatatgcaag gcaacgtggt
    38881 tacctttacc ggtaatgtca tcgtcaccca gggcaccatc aaaattaatg ccgacaaagt
    38941 ggttgttacc cgtccgggcg gcgaacaagg taaagaagtg attgacggct acggtaaacc
    39001 ggcaacgttc taccagatgc aggacaacgg taaaccggtt gaaggtcacg cttcccagat
    39061 gcactacgaa ctggcaaaag attttgtcgt tctgacgggt aatgcttatc tgcagcaggt
    39121 tgatagcaac attaagggcg ataagatcac ttacctggta aaagagcaga aaatgcaggc
    39181 tttcagcgac aaaggcaagc gcgtaaccac cgttctggtg ccgtcgcagc tgcaggacaa
    39241 aaacaacaaa ggccagaccc cggcacagaa gaagggtaat taattcgtta tggcaacatt
    39301 aactgcaaag aaccttgcaa aagcctataa aggccgtcgc gtggtagaag acgtcagcct
    39361 gaccgtcaac tccggggaaa ttgtcggtct gctggggcca aacggtgccg gtaagaccac
    39421 cactttctac atggttgtag gcattgtgcc gcgcgatgcg ggcaacatca ttattgatga
    39481 tgacgatatc agtctgctgc ctctgcatgc acgcgcgcgc cgcggtatcg gctatctgcc
    39541 acaggaagcc tccattttcc gtcgcctcag cgtttacgat aacctgatgg cggtactgca
    39601 aattcgtgac gacttgtctg ctgaacaacg tgaagaccgc gcgaacgagc tgatggaaga
    39661 gtttcacatt gagcacctgc gtgacagcat ggggcagtca ctctccgggg gtgaacgtcg
    39721 ccgtgtagaa attgcccgcg cactggctgc gaatccgaaa tttattctgc tcgacgaacc
    39781 gtttgccggg gttgacccga tctcggttat cgacattaaa cgcatcattg agcacctgcg
    39841 cgacagcggc ctgggcgtgc tgatcactga ccacaacgtg cgtgaaacac tggcggtttg
    39901 tgaacgcgct tatatcgtca gtcaggggca tttgatcgcc cacggcacgc ctacagaaat
    39961 cttacaagac gaacacgtta agcgtgtata ccttggggaa gacttcagac tctgataggg
    40021 tagaagtttg cgacgtttta gcaggagagt acgattctga acatgaagca aggtttgcaa
    40081 ctcaggctta gccaacaact ggcgatgacg ccacagctcc aacaggcaat tcgtctgttg
    40141 cagttgtcga cgctggaact tcagcaggag ctacagcagg cgctggagag taatccgctg
    40201 cttgagcaaa tcgacactca tgaagaaatc gacacccgcg aaacgcaaga cagtgaaacg
    40261 ctggacaccg ccgacgcgct cgaacaaaaa gagatgccgg aagagctgcc gctcgatgcc
    40321 agttgggaca ccatttacac cgctggtaca ccatccggca ccagcggtga ctacattgac
    40381 gatgagctgc cggtctatca gggcgaaacg acgcagacct tgcaggatta cctgatgtgg
    40441 caggtcgagc tgacaccgtt ttccgacact gaccgcgcta ttgctacctc tatcgtcgat
    40501 gccgttgatg acaccggtta tctgactgtc ccgctggaag atattctcga aagtatgggc
    40561 gatgaagaga tcgacatcga cgaggttgaa gccgtcctta agcggatcca acggtttgat
    40621 ccggtcggtg tagcggcaaa agatctgcgt gactgcctgc taatccaact ctcccaattc
    40681 gataaaacca cgccgtggct ggaagaggcc agactgatca ttagcgatca tctcgatctg
    40741 ttagccaatc acgacttccg cactttaatg cgcgtcacgc gtctgaaaga agatgtgctg
    40801 aaagaagccg tcaatctgat ccagtcgctc gatccgcgcc ccgggcagtc gatccagact
    40861 ggcgaacctg agtatgtcat tccagatgtg ctggtgcgta agcataacgg tcactggacg
    40921 gtagaactca acagtgacag cattccgcgt ctgcaaatca accagcacta cgcctcgatg
    40981 tgcaataacg cgcgcaacga tggtgacagc cagtttatcc gcagcaatct gcaggatgcc
    41041 aaatggttga tcaagagtct ggaaagccgt aacgatacgc tactgcgcgt gagtcgctgt
    41101 atcgttgaac agcagcaagc cttctttgag caaggtgaag aatatatgaa accgatggta
    41161 ctggccgata tcgcccaggc tgtcgaaatg catgaatcga cgatatctcg cgtgaccacg
    41221 caaaaatacc tgcatagtcc acgaggcatt tttgaactga agtatttctt ttccagtcac
    41281 gtcaataccg agggcggcgg cgaagcttcc tccacggcga ttcgtgcgct ggtgaagaaa
    41341 ttaatcgcgg cggaaaaccc agcgaaaccg ttgagcgaca gcaagttaac ctctttgctg
    41401 tcggaacaag gtatcatggt ggcacgccgc actgttgcga agtaccgaga gtctttatcc
    41461 attccgccgt caaaccagcg taaacagctc gtttgaccca accgataagg aagacactat
    41521 gcagctcaac attaccggaa ataacgtcga gatcaccgag gcactgcgcg aatttgttac
    41581 agccaaattt gccaaacttg agcaatattt tgaccgaatc aaccaggtct atgttgttct
    41641 gaaagtggag aaagtcaccc acacctcaga tgcaacactg catgtaaacg gtggtgaaat
    41701 tcatgccagc gcggaaggtc aggacatgta cgctgccatt gatggcttaa ttgataagct
    41761 ggcacgccag ttgaccaaac ataaagataa actgaaacaa cactaattgt ccgggcaatt
    41821 agcatgtgca tggcggcctg ttgtgcggca caacgggcca tttgtacggt taatgctccg
    41881 agcctgttcc actgtttgag tgggcaggtt cttaggtgaa attatgacaa ataatgatac
    41941 aactctacag cttagcagtg ttcttaacag ggaatgtacg cgaagccgcg tccactgtca
    42001 gagcaaaaaa cgcgccctgg aaatcatcag cgagctggcg gcgaaacaac ttagtctgcc
    42061 gcctcaggtg gtttttgaag ctatcctgac gcgggaaaaa atgggcagta ccggtatcgg
    42121 caatggtatt gccattccgc atggcaaact ggaagaagat actctgcgcg ccgttggcgt
    42181 tttcgttcag ctcgaaacgc ctatagcttt cgatgccatc gacaaccaac cggtggattt
    42241 actttttgcc ctgctggtgc ctgcagacca aactaaaacg cacctgcata ctctgtcact
    42301 ggtggcgaaa cgtctggcgg acaaaaccat ctgccgccgt ttacgcgcag cccagagcga
    42361 tgaagagctg tatcaaatca ttacggatac cgaaggtact ccggatgaag cgtagttatt
    42421 cggtaatgtc tcttttagac gttgtgagga gaaacagtac atggtactga tgatcgtcag
    42481 cggacgttca ggttcaggta aatctgtcgc cctgcgtgcg ctggaagata tgggttttta
    42541 ctgcgtggat aaccttcccg tagtgttgtt acccgatctg gctcgaactc tggccgatcg
    42601 cgagatttct gccgccgtca gcattgatgt tcgtaatatg ccggagtcac cagaaatatt
    42661 cgaacaggcg atgagtaacc tgcctgacgc tttctcaccg caactcctgt tcctggatgc
    42721 cgaccgtaat accttaattc gtcgttacag tgacacgcgc cgactgcatc cgctttccag
    42781 caaaaacctg tcgctggaaa gtgctatcga caaagaaagc gatttgctgg aacctctgcg
    42841 ttcgcgagcg gatctgattg tcgatacctc agaaatgtcc gttcacgagc tggctgaaat
    42901 gctgcgtacc cgtctgctgg gtaaacgtga acgcgaactg acaatggtct ttgagtcttt
    42961 cggcttcaaa cacggtatcc ctatcgatgc agattacgtc tttgacgtgc gcttcttgcc
    43021 gaacccgcac tgggatccga aactgcgtcc aatgacaggt cttgataagc ccgtcgccgc
    43081 gttcctcgac cgccacacag aagtacacaa ttttatctac cagacgcgaa gctatcttga
    43141 gctatggtta cctatgctgg aaaccaacaa ccgtagctac ctgacggtcg ccattggttg
    43201 taccggcggg aagcaccgtt cggtgtatat tgcagagcaa ctggcagact acttccgctc
    43261 gcgcggtaaa aacgtccagt cacgccatcg tacgctggaa aaacgtaaac catgaccgtc
    43321 aagcaaactg ttgaaatcac aaacaagctg ggcatgcatg cccggcctgc aatgaagctg
    43381 tttgaattaa tgcagggttt tgacgctgaa gtgctgttac gtaatgacga aggcaccgag
    43441 gctgaagcca atagcgttat tgcactgctg atgctggatt ctgccaaagg acggcagatt
    43501 gaagttgaag ccaccggtcc acaggaagag gaagcactgg ccgccgttat cgccctcttt
    43561 aattctggtt ttgatgaaga ttaatcttca tcactttgac attcaaatcc cttcaagctc
    43621 ccccgacaat aagaaaagcg cgtactgaaa tcgttctcaa tcaacgtcat ttgtacattt
    43681 tgtgcgcttt tcactttcag aagaacctta agaaaacctt aagaggcatt gtttaggttt
    43741 tgtttaagtt aatcgaccat actggagatc gtcagaaaat atttccagga gatggcatga
    43801 ttcgcttatc tgaacaaaat cccctgggca ccggaagaca tcggaaatgt tatgcgcatc
    43861 cggaagatgc ccaacgctgt atcaagattg tctaccatcg tggcgatggt ggcgataaag
    43921 agatccgccg tgagttaaag tactacgcgc atcttggtcg ccggttaaaa gactggagtg
    43981 gaataccgcg ctatcacggt accgttgaga cggattgcgg aaccggttat gtctacgatg
    44041 tgattgcaga ttttgacggc aaaccctcca ttacgctgac cgaatttgct gagcaatgcc
    44101 gttacgaaga agacattgca caactgcgcc agctactgaa acagctgaag cgttatttgc
    44161 aggataaccg tatcgtgacg atgtcgctga agccgcagaa tatcctctgt caccgcatca
    44221 gtgagtcaga ggttatcccg gtcgtctgcg acaacattgg tgaaagcaca ttgattccac
    44281 tggcgacctg gtcgaagtgg tgttgtctgc gtaagcaaga gcggttatgg aaacgattta
    44341 tcgcccaacc ggcgctggct attgccctgc agaaagatct gcaacctcgt gagagcaaaa
    44401 cgctggccct cacttcgcgc gaagcttaat ccagctggtg ttgttgcata aacggctcac
    44461 cgcctaactg atacatctgc cgtaaaatcc acgcctgacg gctacgcacg tagcccgatg
    44521 gcgaggagac tttgaaacga agtggattag gtaatacagc tgccagtaat gcagcttccg
    44581 accgggtaag tttgctcgcg ggtttgtgga aataacgttg tgccgcagct tcgacgccaa
    44641 acacaccgtc gccaaattcg gcgatattca ggtaaaccgt caggatacgc tttttgctcc
    44701 agactgtttc tatccccagc gttaatccag cttccagccc ttttcgtacc cagctacgcc
    44761 catcccataa aaagagattt ttggccgtct gctgagaaat cgttgaagca ccgcgaatac
    44821 ggttttcatt gcgctcgttg tgcgccaggg ctttctcaat ggaagcgaca tcaaagcccc
    44881 agtgctcagg aaatttctga tcttctgcgg caatcaccgc cagtcccatc cacggcgaga
    44941 tttgatccat actgacccag tcagaatgtg ccacgtaacg aaaattgcca tgcagccagg
    45001 cgctgacctg tcgctcgacc attaccgctg agaagggaac aggcgcaaca ctaaacaacg
    45061 cgatgccccc gccccagaaa acggcgagga caaccattaa ccgcaaaaga aaacggcgaa
    45121 cgaaactaaa caccgttaag cggcttttac tcattcagcc agaaccagca cgcgggaaac
    45181 cagcttatca atgccgctcg ccgcttctgc aatgttctgc gccagcatat atgctggggt
    45241 ggtgacaatc ttattgtctt catcaaccac gatatcatcg acaggacagg gcacatgctc
    45301 cgcgcccatc tcttccagca cttctgcggt atcgatatca gtaccgatgg tcaaacgcag
    45361 cgggaaatcg aaaattttcg gcagcatcgc tggggcaata cacataaaac caagcggttt
    45421 tccggcctga tgcatcgctt gtgccagcgc ctttaattca cggtcaacgg tgcattcgct
    45481 accaagagtg gcaaaattgc ttaaattctt cgccgcgcca aacccccccg gcacaatcaa
    45541 cgcatccagt tcagcggcat cggcctgggc cagaggacgg atttcaccgc gcgttattcg
    45601 tgccgcttca atcagcacgt tgcgcgtttc cgtcatcgct tcgccagtta aatggttgat
    45661 aacatcaacc tgctgcttat ccggtgcaaa gcagaccgcc tgcgcaccgc tgcgtgaaat
    45721 agctaacaac gtcaacaccg cttcatgaat ttcagaaccg tcatagacgc cgcatccgct
    45781 cagaattacg ccaattttct tcattgtgat catcctttcg caattgactg aaacacatta
    45841 atttttttaa taaaaatggt acgcatcaca catttaactg attcatgtaa caaatcattt
    45901 aagttttgct atcttaactg cgtgcggcct gaaaaacagt gctgtgccct tgtaactcat
    45961 cataataatt tacggcgcag ccaagatttc cctggtgttg gcgcagtatt cgcgcacccc
    46021 ggtctagccg gggtcatttt ttagtggctt ttgccaccca cgctttcagc acttctacgt
    46081 cgtgacgcca ctcttctttc atctcttcaa tccattcacc gacgttatct tcccaggcag
    46141 gaaggtccgg agactgaatt tgctgaccca gctgttgcag atggcgtaac cccactgacc
    46201 ccgccgcacc tttaatttta tgtccttcct ctacaatgcc ttttttatcc tgcgccgtca
    46261 gattcgactc cagcacgctg acatagcccg gcatcatctt ctcaaacacc gctaacccgt
    46321 cggtgatcag cttcggtcct acaagttcga gatactgttc cagcatggga atatcgagca
    46381 atgcttctga tttactgttc tcttctgtcg tcaccgtact ctcctcatca tcctgggtat
    46441 cccagaattt cttgatcatc gcggttagcg ccggaaccga aagcggctta ctcagcacat
    46501 catccattcc agcattgagg tactcttgtt tgtctttcag cacgttagcg gttaaggcca
    46561 ccagcggcgg taaatcctcg cgcggataac gcttcgtcag ttcacgagag atatccagcc
    46621 cggtcatatc tggcaactga atatccagca acaccaggtc gtattcgccc ggtttaaaca
    46681 tctccagcgc cgccttgccg gtcatggcga catcaacgct gttacctaat ttttccagca
    46741 cagaacgcgc aacaatcacg ttcagttcaa tgtcttccac cagcagcaca ttcagcgccg
    46801 gtaaaggcat atcgtcttca tcaaacgcat catcgacctc ttctgctacc gacggtgcgt
    46861 ggatcgtcaa cgtaaaggtt gaacctttgc cctgttcgct ggtaaccgta atatcgccgc
    46921 ccatattttt cgccagacga cgagaaacgg ccagaccaat accggtgccg gtggcaggtt
    46981 taccgccatg actgtctttc acctggtaat acatggcgaa aattttatcc agctcatcct
    47041 gcggaatgcc gataccagag tcttccactt caaaatgcag catatcgcct tcatcgtagc
    47101 gcacgcgcac ggtaacctgg ccttgctggg tgaatttgac ggcgttactg atgaggttcc
    47161 acaggatctg ccgtaaacgc gtcccgtcgg taatgacctg atgcggtaat ggcagcgtcg
    47221 gctccaggtt aaagcgcaat cctttttgtt gcgcctgcaa tgcggagaga ttttccagat
    47281 cggcaaggaa gctggtgaaa tcaaccggtt gattatcaag ctggaccttg cgccgttcca
    47341 tcttatccat gtcgataata tcgttaaaga tattccccag cgtgacggcc gaaacatgga
    47401 tggtcttgag atatttttcc tgctcggcgg tgagttcggt atccagcaga atacggctca
    47461 ggccgacgat accgttcagc ggtgtacgca attcgtgact gatggtggag ataaacgtcg
    47521 ttttgtcgcg gctggcccgt tcaagcgcat cctgataccg cttacgctcg gtaatgtcgc
    47581 gaccaaagcc catcaaaccg tgacgtttac ccacgcggtc gtagtacggc actttacgga
    47641 tttcaaagca ggctttgcgc ccgtccgggt aatccagcca ctgttcatag gtcagtgaca
    47701 cattatgacg gaacactttt tcatcggttt caatgacttt tgcggcggct tccggtgagt
    47761 aaacatcagc aggtttcagg tgaaccagtt gtttttcgct ttttccggtc agcagctcca
    47821 tcgcgcggtt acagccggaa aactctttat cttcgttacg ataaaaaacc aggtcgggtg
    47881 aagcatcaag gaaggaacgt aagaatgagg attgctgctc gagctgaatt tgtgtctctt
    47941 cgcgctcttt gatttcaatt ttcagttggc cgaaggtttc ctgcagttct gcttccgctt
    48001 tttcacgaac ggcgatttcc tgatttagct gggcaatatt atcttttaac tgaacgttga
    48061 ggctcaaatc gcgctcgcgc atctcctcca gtttttgcac cagccgtgac agacgttgtc
    48121 gtgactcctc cagttgctcg acgaccaccg atagaaagta gaccgcccac ggcgtaatca
    48181 gcaaaccaaa gaagatagaa cgaataacat caatgctttc gacctgacca tgcagcacca
    48241 tggttaccgc catttgtacc acaatggcaa gaacgacgag ggccagcgcc agcaacattg
    48301 agaagcgcac cagacctaac ttcatcatca ggtcaacata atactgcgcc agcagacgaa
    48361 tttgcttcat tagggaattc cttcacgaca acctgcccca ataataccca attctgacag
    48421 ttacgttata aattgtgtga gaaatgcgga attcccctca acgacctact ccgttggagg
    48481 tatccacgga cgttccagcg ccgatccctg tacgccatgt tcattcagat agcgatccag
    48541 ctcgaccatt cccgtccatc gattttcgca ccacagagga gcaagcagcg tcgggcgacg
    48601 ggcgctggcg gaaatgcggt ggtagatcac ttccggtggc gtatggcgaa tcatttctcc
    48661 ggcagtgagc gtgtaatcct ccagttcaat accgttcaaa cgccccgctt cccaggcttt
    48721 cgccataatg ctgcctttca caatatgcag cggatgcagc tttatgccgt ccacgccggt
    48781 ttcaaccact cgctccagcg tttgcaaaca ttcagcctgc ccttcgccag gcaggccgac
    48841 aattaagtgg gaacacacct tcagcccgcg ctgacgtgcc agctgggttg tacgctgata
    48901 acaggcaaaa tcatggccgc ggttgatgcg atgcagtgtt ttgtcgtggg cggtttgtag
    48961 ccccagctcc agccacactt cgtaaccctg gtccttatat tcgcaaagca gatccagcac
    49021 cgcatccggc acgcagtccg ggcgggtacc aacacacaaa ccgacaatat tggcctggct
    49081 caccgcctgc tgatacatag aacgcagcac ctgaacttcc gcaaaggtgc tggtatacgc
    49141 ctgaaagtag gccagatagc gtttagcgcg gttaactaaa ttcgcctggt gcgccagttg
    49201 ctcggcaatg gaacgatgct gctgcgcttc atcggcaaac gaggcaacat tacagaatgt
    49261 gcagccacca cgcccgatgg taccgtcacg gttagggcag ctaaaaccgc cgtgtagcgt
    49321 cagcttatgc accttttgcc cataacgacg ggtgagatca ccaccaaaca tattgactaa
    49381 tttctgtaac tgcataatct gatagaccgc gccttgaaaa gaggccaaag cctgccattt
    49441 ttagctcaat tcggcgatga cctggatcaa tcgtcccggc ctgcttttat caactgcata
    49501 atcaatcaaa attaccgaaa tttcatgcat aatcacataa atcacttttg cttatcttgt
    49561 gtcagatttt tttatctcct tatggatttt aggcaaaaac agtagcatga aacgtcatta
    49621 ccaattaagg cagtataaaa tgctggtttt ctcgtcagtt caaggcagga taagggttaa
    49681 cacgccttta tgacagtcag gaattgactg tttctctaac gacttccctt ttagccttaa
    49741 agataaaatc cattttaatt tcagtaattt aataaagaat tttgcgctaa agcacatttc
    49801 tgtaccaata agcttgccat ttgacctgta tcagctttcc cgataagttg gaaatccgct
    49861 ggaagctttc tggatgagca gcctgctcat catatttatg cagtaattga gatcccctct
    49921 tcaccgtatt aaccgatgcg aaaaggacaa caagggggcg aatgcgaggc gcgcgtatga
    49981 cacgcaaacc ccgtcgccac gctctttctg tgcccgtgcg cagcggttcg gaagtggggt
    50041 tcccgcagag cctgggggag gttcacgata tgttgtacga taaatccctt gagagggata
    50101 actgtggttt cggcctgatc gcccacatag aaggcgaacc tagccacaag gtagtgcgta
    50161 ctgcaataca cgcactggcc cgcatgcagc accgtggcgc gattctcgcc gatggtaaaa
    50221 ccggcgacgg ttgcggcttg ctgttacaaa aaccggatcg cttttttcgc atcgttgcgc
    50281 aggagcgcgg ctggcgttta gcaaaaaact acgccgtcgg gatgctattc ctgaataaag
    50341 atcctgaact cgccgctgcc gcacgccgca tcgttgaaga agaactgcaa cgcgaaacct
    50401 tgtcgattgt gggctggcgt gatgtcccca ctaacgaagg cgtgctgggt gaaatcgccc
    50461 tctcctctct gccacgcatt gagcaaattt ttgtgaacgc cccggcaggc tggcgtccgc
    50521 gcgatatgga gcgccgtctg tttatcgccc gccgccgcat tgaaaagcgt ctcgaagccg
    50581 acaaagactt ctacgtctgt agcctgtcga atctggtgaa catctataaa ggtctgtgta
    50641 tgccggcgga tctgccgcgc ttttatctgg atcttgcgga cctgcgtctg gaatcggcca
    50701 tctgcctgtt ccaccagcgc ttctccacta acaccgtacc gcgctggccg ctggcgcagc
    50761 cgttccgcta tctggcgcat aacggtgaaa tcaacaccat caccggtaac cgccaatggg
    50821 cgcgtgcgcg tacctataaa ttccagacgc cgcttatccc tgatctgcac gacgcagcgc
    50881 cattcgtcaa cgaaaccggt tctgactcca gctcgatgga taacatgctg gaactgctgc
    50941 tggcaggcgg gatggatatc atccgcgcta tgcgtctgtt agtgccgccc gcctggcaga
    51001 acaacccgga tatggacccg gagctgcgtg ccttcttcga ctttaactcc atgcatatgg
    51061 agccgtggga tggcccggcg ggcatcgtga tgtccgacgg tcgttttgcc gcctgtaacc
    51121 tcgaccgtaa cggtctgcgt ccggcgcgct acgtcatcac caaagataag ctcatcacct
    51181 gcgcctctga agtcggtatc tgggattatc agcctgacga agtggtcgaa aaaggccgcg
    51241 tcgggccagg cgaactgatg gtgatcgaca cccgcagtgg gcgtattctg cactcggcag
    51301 aaaccgatga cgatctgaaa agccgccatc catataaaga gtggatggag aaaaacgtcc
    51361 gccgactggt accgtttgaa gatctgcccg atgaagaagt gggtagccgc gaactggacg
    51421 acgacacgct tgccagctac cagaaacagt ttaactacag cgcggaagag ctggactccg
    51481 taattcgcgt actgggcgaa aacggtcagg aagcggtcgg ttcgatgggc gatgataccc
    51541 cattcgccgt gctctccagt cagccgcgca ttatttacga ctacttccgc cagcagtttg
    51601 cccaggtgac taacccgcca atcgacccgc tgcgtgaagc gcatgttatg tcgctcgcca
    51661 ccagtatcgg tcgtgaaatg aacgtctttt gcgaagcaga gggccaggcg caccgtttaa
    51721 gctttaaatc gccgattctg ctctactccg atttcaaaca gctcacgacg atgaaagagg
    51781 agcactaccg cgcagatacg ctggatatca cctttgacgt cactaaaacc acgctcgaag
    51841 cgacagtcaa agagctgtgc gacaaagccg aaaaaatggt acgtagcggc accgtgctgc
    51901 tggtgctctc cgaccggaat atcgctaaag atcgcctgcc ggttccagcc ccgatggcgg
    51961 ttggcgcgat ccagacccgt ctggtcgatc aaagcctgcg ttgcgatgcc aacatcatcg
    52021 tcgaaaccgc cagcgcccgc gatccgcacc acttcgccgt gttgctgggc ttcggcgcga
    52081 cggctattta tccatacctt gcctatgaaa cgctgggccg cctggtagac acccatgcga
    52141 ttgccaaaga ttatcgtacc gtgatgctca actaccgtaa cggcatcaac aaaggcttgt
    52201 acaaaatcat gtccaaaatg ggcatctcca ccatcgcctc ttaccgctgc tcgaaactgt
    52261 ttgaagcggt cggtctgcac gatgatgtag tgggcctgtg cttccagggg gcggtcagcc
    52321 gcattggtgg ggcgagcttt gaagacttcc agcaggatct gctgaacctg tcgaaacgtg
    52381 cctggctggc gcgtaagccc atcagccagg gcggcctgct gaaatacgtc cacggcggcg
    52441 aataccacgc ttacaacccg gacgtggtgc gcacgctgca acaggcggta caaagcggcg
    52501 agtacagcga ctatcaggaa tacgcgaagc tggttaatga gcgtccggca accacgctgc
    52561 gcgatctgct ggcaattacg ccgggtgaaa acgcggtcaa cattgctgat gttgaaccgg
    52621 caagcgaact gtttaaacgc tttgataccg ccgcgatgtc tatcggcgcg ttaagcccgg
    52681 aagcccacga ggcgctggcg gaagcgatga atagcatcgg cggtaactcg aactccggtg
    52741 aaggcggcga agacccggcg cgctatggca ctaacaaagt gtcgcgcatc aagcaggtgg
    52801 cttctggtcg cttcggcgtt actccggcgt atctggtcaa tgccgacgtc attcagatta
    52861 aagtcgccca gggcgcgaag ccgggcgaag gcggtcagtt gccgggcgac aaagtcactc
    52921 cttacatcgc caaactgcgc tattcggtgc ccggagtgac gctgatctcc ccgccgccgc
    52981 accacgatat ctactctatc gaggacttag cgcagctcat tttcgacctc aagcaggtta
    53041 acccgaaagc gatgatctcc gtgaagctgg tttccgaacc gggcgtaggc accatcgcga
    53101 ctggcgtggc aaaagcttat gccgatttaa tcaccatcgc aggctatgac ggtggcaccg
    53161 gcgcaagccc gctgtcgtca gtgaaatacg caggttgccc gtgggagctg gggcttgttg
    53221 aaacccagca ggcgctggtt gccaatggtc tgcgtcataa gatccgtttg caggtcgatg
    53281 gcggcctgaa aaccggtgtt gatatcatca aagcggcgat tctcggcgca gaaagcttcg
    53341 gcttcggcac tggcccgatg gtggcgctcg gctgtaaata tctacgtatt tgccatctga
    53401 acaactgcgc aacgggtgta gcaactcagg atgacaaact gcgtaagaac cactatcacg
    53461 gcctgccgtt caaggttacc aattactttg aatttattgc ccgtgaaacc cgcgagctga
    53521 tggcacagct gggcgtaacg cgtctggtgg atctgattgg tcgcaccgac ctgctgaaag
    53581 aactggacgg tttcaccgcc aaacagcaaa aactggcgct gtcgaagctg ctggagaccg
    53641 ccgaaccgca tccaggtaag gcactctact gcaccgaaaa caatccaccg tttgataacg
    53701 gcctgctgaa cgcgcagttg ctgcaacagg cgaaaccgtt tgtcgatgaa cgccagagca
    53761 aaaccttctg gttcgatatt cgcaacaccg accgttctgt cggcgcgtcg ctttcaggct
    53821 atatcgccca aacgcacggc gatcaggggc tggcagccga tcctatcaaa gcgtacttca
    53881 acggcaccgc aggccagagt ttcggtgtgt ggaacgcggg cggcgtggaa ctgtacctga
    53941 ccggggatgc caacgactat gtcggtaaag gcatggcggg cggcttaatc gccattcgtc
    54001 ctccggttgg ttccgccttc cgcagccatg aagcaagtat tatcggcaac acctgcctgt
    54061 atggcgcgac cggtggtcgt ctgtatgccg caggccgcgc gggtgaacgt ttcggcgtgc
    54121 ggaactccgg tgctatcacc gtggtagaag gcattggcga caacggctgt gaatatatga
    54181 cgggcggtat tgtctgtatt ctgggtaaaa ccggcgttaa cttcggtgcg ggcatgaccg
    54241 gcggcttcgc ttacgttctc gatgaaagcg gtgatttccg caaacgcgtt aacccggaac
    54301 tggtcgaggt cttaagcgtt gacgatctgg cgatccatga agagcatctg cgcggtctta
    54361 tcaccgagca tgttcagcat actggctctc agcgcggtga agagattctg gcgaactggt
    54421 caaccttcgc cactaaattt gcgctggtta aaccgaagtc cagtgatgta aaagcactgc
    54481 tgggtcatcg tagtcgtagc gcagcagagt tgcgcgtgca ggcgcagtaa ggggtagcaa
    54541 caatgagtca gaatgtttat caatttatcg acctgcagcg cgttgatccg ccaaagaaac
    54601 cgctgaagat ccgcaaaatt gagtttgttg aaatttacga gccgttttcc gaaggccagg
    54661 ccaaagcgca ggctgaccgc tgcctgtcgt gcggcaaccc atactgcgag tggaaatgtc
    54721 cggtacacaa ctacatcccg aactggctga agctcgccaa cgaggggcgt atttttgaag
    54781 cggcggaact gtcgcaccag accaacaccc tgccggaagt ttgcggacga gtctgcccgc
    54841 aagaccgtct gtgcgaaggt tcctgcactc tgaacgatga gtttggcgcg gtgaccatcg
    54901 gcaacattga gcgttatatc aatgataaag cgttcgaaat gggctggcgt ccggatatgt
    54961 ccggcgtgaa gcaaaccggt aaaaaagtgg cgattatcgg cgcaggcccg gcaggtctgg
    55021 cgtgtgcgga tgtcctgacg cgtaacggcg taaaagccgt tgtcttcgac cgtcatccag
    55081 aaattggcgg gctgctgacc ttcggtattc cggccttcaa gctggaaaaa gaggtaatga
    55141 cgcgtcgccg tgaaatcttc accggcatgg gtattgaatt caaactcaat accgaagtgg
    55201 gccgcgacgt gcagctggac gatctgctga gtgattacga tgccgtcttc cttggcgtcg
    55261 ggacttatca gtcaatgcgc ggcgggctgg aaaacgaaga cgccgatggc gtgtacgcag
    55321 cgctgccgtt ccttatcgcc aacaccaaac agttaatggg ctttggtgaa acccgcgacg
    55381 aaccgttcgt cagcatggaa ggcaaacgcg tggtggtcct tggcggtggc gacactgcga
    55441 tggactgcgt gcgtacgtcc gtgcgccagg gagcgaagca cgttacctgt gcctatcgtc
    55501 gtgatgaaga gaacatgccg ggttcccgcc gcgaagtgaa aaacgcgcgg gaagaaggcg
    55561 tagagttcaa attcaacgtc cagccactgg ggattgaagt gaacggtaac ggtaaagtca
    55621 gcggcgtaaa aatggtacgt accgaaatgg gcgaaccgga tgccaaaggc cgtcgccgcg
    55681 cggagatcgt tgcaggttcc gaacatatcg ttccggcaga tgcagtgatc atggcgtttg
    55741 gtttccgtcc acacaacatg gaatggctgg caaaacacag cgtcgagctg gattcacaag
    55801 gccgcatcat cgccccggaa ggcagcgaca acgccttcca gaccagcaac ccgaaaatct
    55861 ttgctggcgg cgatatcgtc cgtggttccg atctggtggt aaccgctatt gccgaaggtc
    55921 gtaaggcggc agacggtatt atgaactggc tggaagttta agctctgtcc cagcgccgcc
    55981 tcctcagaaa agagtcggcg ctgaaattct cctttctttc tggaaagcgc ctcgcataat
    56041 ctgaagaaaa ccaatgtaat acgctcatct ggattgttac cggtagatgc ccggcgtata
    56101 gctgattcca ttattcaacg cagcgccata taaagggaca gataatggaa tcgctctcag
    56161 agagaacctc aacaggctac cagcaaatcc acgacggtat tattcatctg gtcgatagcg
    56221 cccggacgga aacggtacgt agcgttaacg cgctgatgac cgcgacatac tgggaaattg
    56281 gccgacgaat tgtcgaattt gaacaaggtg gcgaggccag ggctgcgtat ggtgcgcagc
    56341 taatcaagcg actatcaaag gatttaagtc taaggtataa gcgtgggttc tctgcaaaaa
    56401 acttacgcca aatgaggctt ttttacctct tttttcaaca tgttgaaatt cgccagacag
    56461 tgtctggcga attaacacca ttgggaattc cgcagacacc atctgcagaa ttcccatcgg
    56521 caaagatttg gcagacgctg tctgccaaat ctttccccct gccctggtcc acctacgtcc
    56581 gtttactttc cgttaaaaac gctgacgccc gcagctttta tgaaaaagag acgctccgct
    56641 gtggctggtc tgttcgccag ctagaacggc aaattgcgac ccaattttat gagcgaatac
    56701 tactgtcaca tgacaaatca gccatgctgc aacaacacgc tcctaccgag acgcatattc
    56761 ttccgcaaca ggcgatacgc gatccctttg tgctcgaatt tctggaattg aaagatgaat
    56821 attcagaatc tgatttcgag gaggcgctga tcaaccacct gatggatttc atgctggaac
    56881 ttggggatga ttttgccttt gttggtcggc agcgaagatt acgcattgat gacaactggt
    56941 ttcgtgtcga cctgctgttt ttccaccgcc gtttacgctg cctactaatc gtcgatctaa
    57001 aagtgggcaa attcagctat agcgatgccg gacagatgaa tatgtatctc aactacgcca
    57061 aagagcactg gacgctaccg gatgaaaatc cgcccatcgg tctggttctc tgtgcagaga
    57121 aaggagccgg agaagcacat tatgctctgg caggtttgcc taacaccgtt ctggcaagcg
    57181 aatataagat gcaactacct gatgagaaac gactcgcaga tgaactcgtt cgaacacagg
    57241 cggtgctaga ggaaggctat agacgccgtt aatttcagcg gtttcgaatt ctgcagacag
    57301 tgtctgcaga atctttaaaa cgaactaagt tttaagccat taaatcagcc ttaaccttca
    57361 ccaccacctt tttaatctca cccggctcgc caacaacgca tcccggctta tgcggctctc
    57421 ctggcataaa cacggcgaac attcccggtt ttaagatgat ggtttgctcg ttttcaatgg
    57481 cgctgcaaag ctgataatca tcctcatggt ggaactcttc acactgacgc gcggtgcctg
    57541 ccatgccaaa cagaatccgt tcctcaccgt ttaataacag ctggatatca atgtattgct
    57601 cgtgcaattc cgcttttttc tcgacgggcg attgagtgtt aaacgtcatg acattcataa
    57661 agatattgtc gccctgtaat tcgtaacgac ccggcgcttt ttcttgcggt ctggcagcta
    57721 atgccagcgt taacgcgtcc tgtaacgcag gatgtaaccc agcagacggt aatgactgta
    57781 cttcacccat catcataatt tttctccctg ggccaacagc gcagccccaa gtaaacctgc
    57841 atcatggcgg tagtgcgccg ccagtaaatc aacatgaaat gccgctggct cctgcgccag
    57901 atacgtttcc accagcgcca gatacccttc tgccagccca acgctgccac cgaccaccac
    57961 gcactggcaa tcagttgtgg ctttaatatc agcgatcagc cttgccagca catgtgcgga
    58021 gcggtgaatc agttgctgcg cctgctcgtc gccctgcccg gcgcgtgtga aaatagttct
    58081 cgcatccgcg cccatgagtt caccttgcgc tgccgccgca atgccgcgac cagaagcaat
    58141 cgcttccacg caacctgtgc gtccacagcc gcagactggg ccgtgtggat cggcaagcgt
    58201 atgcccgata tgccccgcca gaccgccagg gccggtaagc agtttaccgc cgctcactac
    58261 accgccgccg acgccagtgg aaacggtgat aaacaccatc tcggttacat cgccttccag
    58321 cgcctgatac tctgcccatg ctgcggcctg cgcgtcgtta atggcaatgg tcggcaaatt
    58381 ggtaagttgt tccagcgttt tgactaacgg aaagtgtagc aatccaccga gattatgcgg
    58441 attcagcgcc agcaaactgc cgtcgcgaat aattccggtt gaagcgatgg caacccgctg
    58501 cgcatgagct tgcaacggag agactaatgc ggataaggca tcacgcaagg cttctggtgt
    58561 ctggctggct ggcgtaggaa gttcacgacg atcgcggatc tgcccgtcag cgccaatcag
    58621 cgcggcggca agtttagtac cgccgatatc aatcgccagt gtggtcatag caccgccttt
    58681 ttcatcgctg tgttgtacca ctgacaaatg tgttcaagac gcgtaatggc agaaccgacc
    58741 gtcaccgccc acgcgccgtg gcgcatcgca tcagccgcct gagcaggcgt gttgtaacgc
    58801 ccttcggcaa tcacccgaca tccggcgtcg ctcaacgttt tcaccagcgc cagatccggc
    58861 tcttctggcg tttcaggcgt ggtatagcca gaaagcgtag tgccaataat ttcggctccc
    58921 agcttttggc atgccaggcc gtcttccggc gttgagcagt cggtcatcgc cagtaaaccg
    58981 tgatggtgaa tacgtgccag cagcgtttca acaggcaccg gacgcgggcg gtcggtgccg
    59041 tcaatggcga taatgtccgc gcccgcctgc gccagcgcat cgacatcttc aatataggcc
    59101 gtgatgcgta ccggagaatc ctccagatcg cgtttcacaa tcccgataat tggcacgctc
    59161 accaccgcac gcgtggcttg cagatttgcc acaccttcaa tgcgaatggc aaccgcgccc
    59221 gcctgctctg ccgctaatgc catggcggcg acgatttcgg gtttatcgag cgggctgtcc
    59281 ggaaccggct ggcaggagac aatcaggcca ccgttagcag cgattttttg atccagttgt
    59341 gcaagtaacg acatacatct tcccttagcg aaaggcccgg tacatagacc gggcaacagg
    59401 attaactttt ggttttgact aaatcgtttt tggggctgcc aaatggcacg gcaccgctaa
    59461 atggtttgcc gtcgatagcg tcatgagtac gcaatgcttc cgggcgcagc caacgctgaa
    59521 cgcgggaagg catatccaga ccaatcagca ggatcaccac aaatgtcaga ctgaacgaga
    59581 gcgatgccag cgcagtaccc agatccagac gttgagcgat caacgcgccg atgattgggg
    59641 ccagtgcgcc gcccaatgcg ccaacgttgt aggtaaagcc caggcccgct gcacgctggt
    59701 cggtatcgaa ataaccgcca atcagtttcg gtaagatccc ggcgatccct tgtccaagca
    59761 tttgctggaa gaacagtaac agaccgagca cccagacgtt tgcgccgcca atcgcaaata
    59821 ccggaataat cagcagctgc gaggccagca ggctacaaac gtacgctttg cgggttccca
    59881 gccagtcacc gaggaagcca cctacgcagc atcccacggc cgcgccaaag ccactaaaga
    59941 acagcacatt ggcgacagta tgcgggttat aagccagatc ggttttcaga tacgttggca
    60001 gcagcgcctg aatcggccat gagtagagga aagcaaacaa cacgaccacc atcagcatta
    60061 cgcccgttgg ccagcgttta cccgtacttt gcaccataaa gctgataaag attgcggcgc
    60121 ataacagccc gagaacagcg acgattgcag cattttgcag gttaccggcg aagcagaacc
    60181 acagcgcagt agccgccgcc agtgtcatta cgatattggc aatgcgatgt tcaccacggt
    60241 agagaatatc caccattgtg cgtactggtg ctttacctgc gtgtttctct ttccagtctt
    60301 ccgcttccgg gatgttttta cgcagccaga gagcaaagat gattggcaaa atgccgataa
    60361 agaacagcgc acgccaaccc cagaccggaa ccaccaggct atagacctga gcggcaacga
    60421 cggcccccac agagaagcct gaaatcaaaa aaccactggc tttgttacgc agatgttttg
    60481 gccagctttc aatgacatag gtggcgctgg aaccgtattc acccgccatc cccatgccga
    60541 tgaccagacg agcgataaac atggtgatgt agcctggcgc aaagccgcag gccagcgtcc
    60601 cggccgagaa gagaacgatg ctggtgacca ttgccagacg acgcccgtag cggtcaccca
    60661 tagcgccgag catcaggccg ccgaaccagc gagagataaa ggctgcggag atcagacttg
    60721 ccgcctgcac cgtcgtcagc ccgaattcac cctgtacttc ggtgagtacc agggcgatta
    60781 aaacgaaatc aaaaccgtca agcagatatc ccaaccaggc agcggaaaat gcccgccatt
    60841 gtgcacgatt gagatggcga taccacggga tattctgggt tgtagtactc attgtgagtc
    60901 tcccgcggtg ggcgatgccc acacgctttg gtatgaaaat tgtagggtac agatgcgttt
    60961 atttcccctc acccggtagg ggcgagcgag gggaaacaac tcacccgcgc tcttgcatca
    61021 actgctgggc cagcgccttc agttctggca gatatttttc atctaccgga ccaaacggtt
    61081 tgcggcacag cggcacagaa acgacatcca tataatgcag gacagttttc aggccgcgga
    61141 atacgcccgt tttgatcagt aaatcaatga ctttattaca ttcggtttgc agcttctgcg
    61201 cggtctggat atcgccttct ttcagcgcct tcacaatccc ctgataacgc cagcccatga
    61261 tgttgtaggt actaccgata ccaccatcag cgcccgccag aagaccagag gcgaagattt
    61321 cgtcgtaacc gttatagagc accagatcag gatgttcacg acggatctgc tccatctgat
    61381 agagatcgcc agaggtctgt ttcagcgcac ctacgccagg caacgtaaca agtgtgttga
    61441 tctgatccag ggtcagtttt accccactca gggctggaat gttgtacacc accatcggca
    61501 aaccatccgc cgaatcaata attgcccgat agtgatcgca gtgttcttca aagctgaaag
    61561 gatagtagaa cggcgtgacg gcggagacgg catcgaagcc ataacgttta gccgatgccg
    61621 caagttgttg gctttcggcg gtgctgacgc aaccgacgtg ggcgatgagt ttaatctgac
    61681 ctttcgcctc ttcggcgacg atttccagta cctgttcacg ctcggaaagg ctttgtacaa
    61741 aggcctcgcc ggtcgaacca cccacgtata aaccgtcgat gccctgctga atattgaact
    61801 gaaccaggcg acgcagactc gctttatcca gtgcttgttg ttggtcaaaa ggagtcagga
    61861 gtgcagccat tacgccacgt aaattcgttg ccataaatac ctctgaagtg atgcttgtct
    61921 gataaacgat atacctttat acctgttata ccagatcaat taagcaacac cccatacaga
    61981 aagcttataa tgcgatctgc ttcactaaag tggcattatt tctttttgtt ggtggtctga
    62041 ccgaaagcgt gccaggtagc agagacgctg ttgagatgcg attgcaacgc acgatcggct
    62101 tcgtcaggat catgacggcg gatcgcatca acgatcgcaa tatgctgttg ataactaacg
    62161 ttgttatgtt cgtgcagtgc ctgatcggta accgttgggc gtgcggcaat aagccagtcg
    62221 agcagggcaa cgtggatcgc catgaagatt gggttaccgg ggatctccgc cagcacgcgg
    62281 tggaaatcaa cgtctgaacg aatgaatgcc gcgttgttat ccagcgactg actgttgatt
    62341 tccagtgctt ttgccagcaa atcgatttgc tcatcggtgg catgttcagc cgcatagcgc
    62401 accaggctgg attcaaagaa cagacgtaat tgttcgaaat gggcaatccc accaggatga
    62461 gaaaggaaat ctttcgccat gccggaaagc tcgccgatga tggtgtccgc agaaggacgt
    62521 gagacgcggg cacgttcgcc gttgttgatt tgcaccagac ctttgcgttt taacgctgcc
    62581 agcgcttcgc gcacagaagg acgcccgacg ttaaagaacg ccatcagttc gcgttcagac
    62641 ggtaattgtt caccttcgcc aaattcacga cggcggatca tctgttccag ctcttcttcc
    62701 accatttcgg agagtttttt acgcgccagc gggcggctac gcaagttgcg accaattgca
    62761 ggtgaagaat cttcggtttg cgaatcaaat gcgttcataa ggcccattct gtaaggtcag
    62821 tgtgattaac atcatcagtg acatcctatc acaggattga aagtagggga aaatggcagg
    62881 tttttctctt tgtgcctcat cattaccata attaacggaa taattaacta ttgcgaaaaa
    62941 ttaatgtaac gcagataaaa acatcccgtt tgaattattt ataagactat tcacgagcat
    63001 tatgaatatt atgaatgtgt tcttacaaaa taatcataag cgcatatttt ttaatgaaaa
    63061 atcacctcac ctacaattaa aaacacgaca tccgcaccat aaatagactt gcaaaaaata
    63121 taacatcatt gttttcaatc tgccgtttat gggattgacc gttttctttt gacacggagt
    63181 tcaacaatgt tcggcataat tatatctgtc atcgtattaa ttacgatggg ctatttgatc
    63241 ctgaaaaact acaaacctca ggtgctgctg gctgccgcag gtatcttcct gatgatgtgc
    63301 ggtgtctggt tagggttcgg tggtgtactc gatcccgcca aaagcagcgg ctacttgatc
    63361 gtcgatattt ataatgaaat cctgcgcatg ctgtccaacc gcattgccgg attggggctg
    63421 tcgattatgg cggtgggcgg ttatgcccgc tacatggagc gcacaggagc cagtcgcgcg
    63481 atggtgagct tgctaagccg cccgttaaaa ctcattcgct cgccgtatat tattctgtcg
    63541 gcaacttacg tcatcggcca aatcatggcg cagtttatta ccagcgcctc cggcctgggt
    63601 atgttgctga tggtcacctt atttccgacg ctggtgagtc tgggagtaag tcgcctctct
    63661 gcggtggcgg ttatcgcaac cacgatgtcc attgagtggg ggattctgga aacgaactcc
    63721 atttttgcag cccaggtcgc gggaatgaaa attgccactt acttcttcca ctaccagctt
    63781 ccggtcgcct cttgcgtcat tatctcggtg gcgatctccc actttttcgt gcaacgcgct
    63841 tttgacaaaa aagataaaaa tatcaatcac gaacaggcag agctaaaagc tctcgataat
    63901 gtcccgccgc tctattacgc cattttacct gtgatgccgt taatcttgat gctcggctcg
    63961 ctgttcctcg cccacatcgg gctgatgcag tcagaactgc atctggtggt ggtgatgtta
    64021 ctgagtttga cggtgacgat gtttgttgag ttcttccgca agcataactt gcgcgaaaca
    64081 atggacgatg tgcaagcgtt ttttgacggc atgggtacgc agtttgccaa cgtggtaacg
    64141 ctggtggtcg cgggtgaaat atttgcgaaa ggcttaacga cgattggcac tgttgatgcg
    64201 gttatcaggg gtgcggagca ttctggtctg ggcggtattg gcgtgatgat tattatggcg
    64261 ctagtcattg ccatttgtgc cattgtgatg ggctctggca atgcgccgtt tatgtcattt
    64321 gccagtctta ttccgaatat cgcagccgga ttacatgtac cagcggttgt aatgattatg
    64381 ccgatgcatt ttgccacgac gctagcgcgc gcggtttcgc cgattactgc ggtggtggtc
    64441 gttacgtcag gaattgcagg cgtttcgcct tttgcggtgg tgaagcgaac agcgatcccc
    64501 atggcagtcg gtttcgtggt gaatatgatt gccacaatca cgctatttta ttaagccatt
    64561 aaaagacaaa acaggccacc agggcctgtt tttgtattac ttcacaacgc gtaatgccgg
    64621 tcgaccaccg cgtggtggct gcggaagttc atcgtcagga tgagtgtcat catcgtgatc
    64681 tggcttgtcg ccatcaataa ccgacataac ggtttcgttg tctgccgatg cctcttcatc
    64741 attcatgatg ctggtatctt catcgtaggc agcttcaggc tcaaacatcg tgcctgcgcc
    64801 attttcacgg gcgtagatag ccagcacggc agccagcggc acagaaacct gacgcggaat
    64861 gccgccaaag cgcgcgttaa agcgtacctc atcattcgcc agttccagat tgccgacagc
    64921 acgcggcgca atgttgagta cgatttgccc gtcacgcgca tattccatag gaacctgcac
    64981 gccagggagc gtcacatcca ccaccaagtg cggcgtgagc tggttatcca gcaaccactc
    65041 atagaatgca cgcagcagat agggacgacg tggtgttagc tgtgacaaat ccatacagat
    65101 taactccggc ccagacgcat ttcacgttct gcttcagtta aagaagcaag gaaagagtca
    65161 cgctcaaaga cgcgggtcat atagcctttc agctctttcg cacccgggcc gctgaactcg
    65221 atgcccagtt gcggcagacg ccacagcagc ggagcaagat agcaatcgac caggctgaac
    65281 tcatcgctca ggaagtacgg cttctgaccg aagaccggcg caatcgccag cagttcttcg
    65341 cgcagttgct tacgtgcggc atctgcttca gaagctgaac cgttgatgat ggtgttcatc
    65401 agcgtgtacc agtctttttc gatgcgatgc atgtacagac ggctttcacc gcgagctacc
    65461 gggtaaacag gcatcagtgg cggatgcggg aaacgctcat ccagatattc cataatgatg
    65521 cgagattccc acagggtcag ctcacgatcc accagggtcg gaacgctctg attcgggttg
    65581 aggtcaatca gatcctgagg cggattgtcc ttttccacgt gttcgatctc gaaacttaca
    65641 cctttctcag ccagcacaat gcggacctga tggctataga tgtcagtagg accggaaaac
    65701 agcgtcatta ccgaacgttt gttggcagcg acagccatga aaacctccag gtatagtcag
    65761 aatttttact gctaccagcc accaggtggc cagtcagaag ttgtgttacc cagtaaggaa
    65821 cgactctctt tgttcgaaaa tcaaacaaaa aatgagcaat acccgacatt tgggcagaaa
    65881 attggatgat agtttaccag attttgcgac ctttgtggtg agtcgatgcc ggaaatgggg
    65941 aaaaagagat gcgctttagt ctgaaatagt tgacttagtc ccttattggc gatgtggttt
    66001 ttgttttgcc tgtctgtcag acggtagcaa aaagcaactt tccaattttt acgctgattc
    66061 agaatttaac cataaaaaaa cccgccgaag cgggtttttt cgcaaattgt tttctgccgg
    66121 agcagaagcc aattaacgtt tggagaactg cggacgacga cgtgctttac gcagaccgac
    66181 tttcttacgt tcaacctgac gagcgtcacg agtaacgaag ccagctttac gcagttcaga
    66241 acgcagggac tcgtcgtatt ccatcagagc gcgggtgata ccgtgacgga tcgcaccagc
    66301 ctgaccagag ataccaccac ctttaacggt gatgtacagg tccagtttct caaccatgtc
    66361 gaccagttcc agcggctgac gaactaccat gcgagcagtt tcacgaccga agtactgttc
    66421 cagagaacgt tggttgatta cgattttacc gttgcccggt ttgatgaaaa cgcgagctgc
    66481 ggaacttttg cggcgaccag tgccgtagta ttgattttca gccattgcct ataatcccga
    66541 ttagatgtca agaacttgcg gttgctgtgc cgcgtggttg tgctcgttac ccgcgtaaac
    66601 tttcagttta cggaacatag cacgacccag cgggcctttt ggcaacatgc ctttaaccgc
    66661 gatttcaatc acacgctcag gacggcgagc aatcatctct tcaaaggtcg cttgtttgat
    66721 accaccgatg tggccggtgt ggtgatagta cactttgtca gtacgcttgt tgccggttac
    66781 agcaactttg tcagcgttca gaacgatgat gtaatcaccg gtatctacgt gcggagtgta
    66841 ttccgctttg tgcttaccgc gcaggcgacg agccagttca gtagccagac ggcccagagt
    66901 tttaccggtc gcgtcaacaa cataccagtc gcgttttacg gtttctggtt tagctgtaaa
    66961 agttttcatt aaaagcttac ccaataaata gttacacgtt ggtgaacacc caaacgtctt
    67021 caattgttga ggttcacacg acaaagtccg gcaaacctac cccttcgaat agcctatgcc
    67081 agcacacaaa aagttttggg aaaaaaactt tcttgtaacg tggggtcgca ggattataga
    67141 gaagtcgggg tcaaagatcg accccttttt gtgatttgtg acaggtttta acccgccaaa
    67201 tgctcgcgct tcagatactc ttcgctttgc atctcttgca gacgtgacag gcaacgctgg
    67261 aactcaaact tcagccgatc gccctgataa atttcataca gcggcacttc tgcactcacc
    67321 actaatttga catggcgctc gtaaaactca tccaccagcg caataaagcg ccgcgcttcg
    67381 ctctccatca accgcgtcat aactggtaca tcaaacaaca tgaccgtatg aaagagacgt
    67441 gagagcgcaa tatagtcatg ctgactgcgg gcgtcgacgc acagcgtagt aaaagagacc
    67501 gccagcgtct ggttctcgac gcccattgtc gccaatggcc gatggttgat ttctaacgtc
    67561 ggtgaatttt ctcgtttcgc ccccgccagc gccaaccata gtttatccat ctgcgcccgg
    67621 gtttcatcgt tgagtggcga aagccacaga tgcgcctgag tgagtgtacg cagtcgataa
    67681 tcaacaccag cgtccacgtt cattacatca caatgctgtt taatggcatc gattgcaggc
    67741 agaaaacgcg cacgttgcag gccatttcga taaagttcat ccggcggaat atttgacgtc
    67801 gctaccaggg taatgccgcg ggcgaacagg gctttcatca gaccgccaag tagcatggcg
    67861 tcggtaatat cagaaacaaa aaattcgtca aaacagagca cgtcagtttc ggctttaaag
    67921 cgatcggcaa taatttccag cggatcggtc tgcccctgta aggcagttag ctcttcgtgc
    67981 acccgcagca taaaacggtg aaagtgcagg cgctgtttcc gctctcccgg caggctttga
    68041 tagaaaaggt ccatcagcca ggttttcccg cgtcctacac cgccccacat atataagcca
    68101 cgcactggcg tatgctttgt gtcttcgcgt ttaccccaca gcttaccgac ccgcgccatt
    68161 agcccactcg tcctgggggc tggtggcctg ctattgatga gttcttgata aataatttcc
    68221 aggcggctga cggcctcttt ttgaacgtcg tcgggttgat ggctgccttc attgagcgcc
    68281 ttcaggtatt gcgatgttgg ggtaacgctt tgcatgatct tattgttatt ccttgaataa
    68341 tcggtgcgcc gttgttcacg gttgacgaaa aaaaggccgt tctacactac gcgatatgca
    68401 gtcgggattc cacttctgtg gaattaacgg ttatagtggc ataatcagcc gcaggcatgg
    68461 agcctgaagc caacacccta cggaaacaaa agacaacggg agatgttcat gacctgggaa
    68521 tatgcgctaa ttgggttagt cgtcggcatc attattggtg ctgtggccat gcgttttggt
    68581 aatcgtaaac tacgccagca acaggcgttg cagtacgaac tggaaaagaa taaagctgaa
    68641 ctggacgagt atcgcgaaga gctggttagc cactttgccc gcagcgcgga attactggat
    68701 accatggcgc acgactatcg ccagctgtat cagcacatgg cgaaaagctc cagcagcctg
    68761 ctgccggaac tgtctgctga agcaaacccg ttccgtaatc gtctggcaga gtctgaagcc
    68821 agcaacgatc aggcaccggt gcagatgcct cgcgactatt ctgaaggcgc atccggcctg
    68881 ctgcgtactg gcgcgaagcg cgactaattt atttttcggg cgcagccatt gcgccctcct
    68941 cttctctccc tccccgacta tcatttaatc tggtgtctca ttgttagccg tctgaaaatt
    69001 caataacatc aaactgtttt gaatctcttt tcttatcatt caggtacgag agcaggaata
    69061 atgaaaaaac aaacccagct gttgagtgca ttagcgttaa gtgtcgggtt aactctctcg
    69121 gcgtcatttc aggccgtcgc gtcgattcca ggccaggttg ccgatcaggc ccctctcccc
    69181 agtctggctc caatgctgga aaaagtgctt ccggcagtgg tgagcgtacg ggtggaagga
    69241 acggccagtc agggacagaa aatcccggaa gaattcaaaa agttttttgg tgatgattta
    69301 ccggatcaac ctgcacaacc cttcgaaggt ttaggttccg gtgtcatcat caacgccagt
    69361 aaaggctatg tgctgaccaa caaccatgtg attaatcagg cacagaaaat cagtattcag
    69421 ctcaatgatg ggcgcgagtt tgatgcaaaa ctgattggta gcgatgacca gagcgatatc
    69481 gccctgttac aaattcaaaa cccgagcaaa ttaacgcaaa tcgctattgc cgactccgat
    69541 aaattgcgcg tcggtgattt tgccgtagcg gtcggtaacc catttggcct tgggcaaacc
    69601 gccacctctg gcattgtttc cgcattaggc cgcagcgggt tgaatcttga aggtctggaa
    69661 aactttatcc agacagatgc ttccattaac cgcggtaact ccggcggtgc actattaaac
    69721 cttaacggtg agttaattgg catcaacact gcaatccttg cgcctggcgg cgggagcgtc
    69781 gggattggat ttgccatccc cagtaatatg gcgcgaacac tggcgcagca gcttatcgac
    69841 tttggtgaaa tcaaacgcgg tttgttaggc atcaaaggca ccgagatgag tgccgatatc
    69901 gccaaagcct tcaaccttga cgtgcagcgt ggcgcgtttg tcagcgaagt gttgccaggt
    69961 tctggctcgg caaaagcggg cgtcaaagcg ggcgatatta ttaccagcct caacggcaaa
    70021 ccgctgaata gctttgctga gttgcgctct cgtatcgcga ccaccgagcc gggcacgaaa
    70081 gtgaagcttg gcctgctgcg taacggcaaa ccactggaag tagaagtgac gctcgatacc
    70141 agcacctctt cgtcggccag cgctgaaatg atcacgccag cgctggaagg tgcaacgttg
    70201 agcgatggtc agctaaaaga tggcggcaaa ggtattaaaa tcgatgaagt tgtcaaagga
    70261 agcccagctg ctcaggctgg cttgcaaaaa gacgatgtga tcattggcgt caaccgcgat
    70321 cgggtgaact cgattgctga aatgcgtaaa gtgctggcgg caaaaccggc catcatcgcc
    70381 ctgcaaattg tacgcggcaa tgaaagcatc tatctgctga tgcgttaatg tcgtaaaccg
    70441 ggcatcaggc ttacgtgtga tgtccggtta actcgtggta tgctgctgcc gttccctttt
    70501 ttaatgacgc ctccatcatg tttgtgaagc tcttacgttc cgttgcgatt ggattaattg
    70561 tcggcgctat tctgctggtt gccatgcctt cgctgcgcag ccttaacccg ctttccactc
    70621 cgcaatttga cagtaccgat gagacgcctg ccagttataa tctggcggtt cgccgcgccg
    70681 cgccagcggt ggttaacgtt tacaaccgtg gtttgaacac caactctcac aaccagcttg
    70741 agatccgcac cttgggatcc ggtgtaatca tggatcaacg cggttatatc atcaccaata
    70801 aacacgtcat caacgacgcc gatcagatca tcgtcgcctt acaggatggt cgtgtatttg
    70861 aagcattgct ggtgggatct gactctctaa ccgatctggc ggtacttaaa attaatgcca
    70921 ctggcggttt acctaccatt ccgatcaatg cacgtcgcgt accgcacatt ggcgacgtgg
    70981 tactggcgat cggtaacccg tacaacctcg ggcagaccat tacccagggg attattagtg
    71041 ccacgggtcg aatcggtctg aacccgaccg ggcggcaaaa cttcctacaa accgatgctt
    71101 ccattaacca cggtaactct ggcggcgcgc tggtgaactc gctgggagaa ctgatgggca
    71161 ttaacacgct gtcgtttgat aagagtaacg atggcgaaac gccggaaggt atcggctttg
    71221 cgattccttt ccagttagca accaaaatta tggataagct gatccgcgat ggtcgcgtga
    71281 tccgcggcta cattggtatc ggcggacgcg agatcgcacc actgcacgcg cagagcggtg
    71341 gtatagatca actgcaaggg atcgtggtta atgaagtgtc acctgacggc ccagcggcga
    71401 atgcgggtat tcaggtcaac gatctgatta tttcggtgga taacaaaccg gccatctctg
    71461 ctctggagac gatggatcag gtggcggaaa ttcgccctgg ttcggtgatc ccggttgtag
    71521 tgatgcgtga tgataagcag ttaacgctgc aggtcaccat tcaggaatat ccggcaacca
    71581 attaagtcga gtgctcaaaa caaaaaccgg agtctgtgct ccggtttttt attattcgct
    71641 aatcaattac ttattaacga actcttcgcc cagggcgata tctttcttca gcgtatccag
    71701 cataccttcc agcgcgttct gttcaaatgc gctcagggta ccgatagatt tacgctcttc
    71761 cacgccgttt ttacccagca gcagcggttg agagaagaaa cgggcgtact gaccgtcgcc
    71821 ttcaacgtag gcacattcga caacgccttg ttcgccctgc agtgcacgaa ccagagacag
    71881 accaaaacgt gcagctgcct ggcccataga cagggttgca gacccgccac cggctttcgc
    71941 ttcaaccacc tcagtacccg cgttctggat acgtttggtc agatcagcca cttcctgctc
    72001 ggtaaaacta acgccaggaa cctgtgacag cagcggcaga atggtaacac cagagtgacc
    72061 gccaataacc ggcacttcaa cttcgcctgg ctgtttgcct ttcagttccg caacaaaggt
    72121 gttggaacga atgatatcca gcgtggtaac gccgaacagt ttgtttttgt cataaacacc
    72181 ggcttttttc agcacttcag cagcaattgc aacagtggtg ttaaccgggt tagtgataat
    72241 accaatgcac gctttcgggc aggttttcgc aacttgctgt accaggtttt tcacgatgcc
    72301 ggcgttaacg ttaaacaggt cggaacgatc catacccggt ttacgcgcta cacctgcaga
    72361 gataagaacg acatctgcgc cttccagcgc cggagtcgca tcttcaccag aaaaaccttt
    72421 gattttcaca gcagtaggga tatggctcag atcgacggcc acaccgggag tcactggagc
    72481 gatatcatac agagagagtt ctgaacctga aggcagttgg gtttttaaca gtagtgcaag
    72541 cgcctggcca ataccgccag cagcgccgag gactgcgact ttcatcctaa actccttatt
    72601 atattgataa actaagatat gttgctccgc tgccgcgacc ttaatccaca aaattgccgt
    72661 ttacaatgac cacatctcaa gaatgtgtag tcacgcaagt ttagcgttta tgcatttaat
    72721 tgccgtaatc aggaacctaa cttacgtaat taacagtcgc ttatgcatta gcgcaacatt
    72781 ccaacaggtg gtgacaatat accctaccgt tcagccaaaa caacatcaat ttgataacaa
    72841 ttaatttact tttaagcaga atttgcatgc cgtgacgcag gcatgtttct caataacgaa
    72901 atttgataaa atcccgctct ttcataacat tatttcagcc ttcttcaggg ctgactgttt
    72961 gcataaaaat tcatctgtat gcacaataat gttgtatcaa ccaccatatc gggtgactta
    73021 tgcgaagctc ggctaagcaa gaagaactag ttaaagcatt taaagcatta cttaaagaag
    73081 agaaatttag ctcccagggc gaaatcgtcg ccgcgttgca ggagcaaggc tttgacaata
    73141 ttaatcagtc taaagtctcg cggatgttga ccaagtttgg tgctgtacgt acacgcaatg
    73201 ccaaaatgga aatggtttac tgcctgccag ctgaactggg tgtaccaact acctccagtc
    73261 cattgaagaa tctggtgctg gatatcgact acaacgatgc agttgtcgtg attcatacca
    73321 gccctggcgc ggcgcagtta attgctcgcc tgctggactc actgggcaaa gcagaaggta
    73381 ttctgggcac catcgctggc gatgacacca tctttaccac ccctgctaac ggtttcaccg
    73441 tcaaagacct gtacgaagca attttagagc tgttcgacca ggagctttaa tctctgcccc
    73501 gtcgcttctg gcggcgggga aaatgttgct tatccctctc attccccttc tttctcctgc
    73561 gatacattta acgaatagtg cgttttaccg cgacacatca ttcacaaaat gaatacatac
    73621 ggtaaaaaaa gcacattatg caaaattcat tatctaattg aaaatactat aattaataat
    73681 aaataaccgt gttttttata cttttt
//
LOCUS       DAPGUL010000010        72251 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.010, whole genome shotgun sequence.
ACCESSION   DAPGUL010000010 DAPGUL010000000
VERSION     DAPGUL010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 72251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 72251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..72251
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.010"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(164..240)
                     /locus_tag="RHX21_000762"
     tRNA            complement(164..240)
                     /locus_tag="RHX21_000762"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(204..206),aa:Arg,seq:acg)
     gene            complement(438..514)
                     /locus_tag="RHX21_000763"
     tRNA            complement(438..514)
                     /locus_tag="RHX21_000763"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(478..480),aa:Arg,seq:acg)
     gene            complement(518..610)
                     /locus_tag="RHX21_000764"
     tRNA            complement(518..610)
                     /locus_tag="RHX21_000764"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(574..576),aa:Ser,seq:gct)
     gene            complement(926..1111)
                     /gene="csrA"
                     /locus_tag="RHX21_000765"
     CDS             complement(926..1111)
                     /gene="csrA"
                     /locus_tag="RHX21_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HDV1985993.1"
                     /translation="MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHR
                     EEIYQRIQAEKSQQSSY"
     gene            complement(1346..3976)
                     /gene="alaS"
                     /locus_tag="RHX21_000766"
     CDS             complement(1346..3976)
                     /gene="alaS"
                     /locus_tag="RHX21_000766"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HDV1985994.1"
                     /translation="MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPHNDPTLLFTNAGM
                     NQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDY
                     FKHDAIQFAWELLTSEKWFALPKERLWVTVYESDDEAYEIWEKEVGIPRERIIRIGDN
                     KGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQ
                     FNRQADGTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFRTLIQAVAKVTGATDL
                     SNKSLRVIADHIRSCAFLIADGVMPSNENRGYVLRRIIRRAVRHGNMLGAKETFFYKL
                     VGPLIDVMGSAGEDLKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLSGDTLDG
                     ETAFRLYDTYGFPVDLTADVCRERNIKVDEAGFEAAMEEQRRRAREASGFGADYNAMI
                     RVDSASEFKGYDHLELNGKVTALFVDGKAVDAINAGQEAVVVLDQTPFYAESGGQVGD
                     KGELKGANFSFAVEDTQKYGQAIGHIGKLAAGSLKVGDAVQADVDEARRARIRLNHSA
                     THLMHAALRQVLGTHVSQKGSLVNDKVLRFDFSHNEAMKPEEIRAVEDLVNAQIRRNL
                     PIETNIMDLEAAKAKGAMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRI
                     ISESGTAAGVRRIEAVTGEGAITTVHADSDRLSEVAHLLKGDSNNLADKVRSVLERTR
                     QLEKELQQLKEQAAAQESANLSSKAIDVNGVKLLVSELSGVEPKMLRTMVDDLKNQLG
                     STIIVLATVAEGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTD
                     AAALPAALASVKGWVSAKLQ"
     gene            complement(4104..4604)
                     /gene="recX"
                     /locus_tag="RHX21_000767"
     CDS             complement(4104..4604)
                     /gene="recX"
                     /locus_tag="RHX21_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HDV1985995.1"
                     /translation="MTESTSRRPAYARLLDRAVRILAVRDHSEQELRRKLAAPIMGKN
                     GPEEIDATAEDYERVIAWCHEHGYLDDSRFVARFIASRSRKGYGPARIRQELNQKGIS
                     REATEKAMRECDIDWCALARDQATRKYGEPLPTVFSEKVKIQRFLLYRGYLMEDIQDI
                     WRNFAD"
     gene            complement(4847..5908)
                     /gene="recA"
                     /locus_tag="RHX21_000768"
     CDS             complement(4847..5908)
                     /gene="recA"
                     /locus_tag="RHX21_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HDV1985996.1"
                     /translation="MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTG
                     SLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDP
                     IYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEI
                     GDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKF
                     YASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELV
                     DLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPNS
                     TPDFSVDDSEGVAETNEDF"
     gene            complement(5988..6485)
                     /gene="pncC"
                     /locus_tag="RHX21_000769"
     CDS             complement(5988..6485)
                     /gene="pncC"
                     /locus_tag="RHX21_000769"
                     /EC_number="3.5.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide-nucleotide amidase"
                     /protein_id="HDV1985997.1"
                     /translation="MTDSELMQLSEQVGQALKARGATVTTAESCTGGWVAKVITDIAG
                     SSAWFERGFVTYSNEAKAQMIGVREETLAQHGAVSEPVVVEMAIGALKAARADYAVSI
                     SGIAGPDGGSEEKPVGTVWFAFATARGEGITRRECFSGDRDAVRRQATAYALQTLWQQ
                     FLQNT"
     gene            complement(6630..7715)
                     /gene="mltB"
                     /locus_tag="RHX21_000770"
     CDS             complement(6630..7715)
                     /gene="mltB"
                     /locus_tag="RHX21_000770"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic murein transglycosylase B"
                     /protein_id="HDV1985998.1"
                     /translation="MFKRRYVTLLPLFVLLAACSSKPKPTETETTTGTPSGGFLLEPQ
                     HNVMQMGGDFANNPNAQQFIDKMVNKHGFDRQQLQEILSQAKRLDSVLRLMDNQAPTT
                     SVKPPSGPNGAWLRYRKKFITPDNVQNGVVFWNQYEDALNRAWQVYGVPPEIIVGIIG
                     VETRWGRVMGKTRILDALATLSFNYPRRAEYFSGELETFLLMARDEQDDPLNLKGSFA
                     GAMGYGQFMPSSYKQYAVDFSGDGHINLWDPVDAIGSVANYFKAHGWVKGDQVAVMAN
                     GQAPGLPNGFKTRYSISQLATAGLTPQQPLGNHQQASLLRLDVGTGYQYWYGLPNFYT
                     ITRYNHSTHYAMAVWQLGQAVALARVQ"
     gene            7971..8534
                     /gene="srlA"
                     /locus_tag="RHX21_000771"
                     /gene_synonym="gutA"
     CDS             7971..8534
                     /gene="srlA"
                     /locus_tag="RHX21_000771"
                     /gene_synonym="gutA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDV1985999.1"
                     /translation="MIETITHGAEWFIGLFQKGGEVFTGMVTGILPLLISLLVIMNAL
                     INFIGQHRIERFAQRCAGNPVSRYLLLPCIGTFVFCNPMTLSLGRFMPEKYKPSYYAA
                     ASYSCHSMNGLFPHINPGELFVYLGIASGLTTLNLPLGPLAVSYLLVGLVTNFFRGWV
                     TDLTTAIFEKKMGIQLEQKVHLAGATS"
     gene            8531..9490
                     /gene="srlE"
                     /locus_tag="RHX21_000772"
                     /gene_synonym="gutE"
     CDS             8531..9490
                     /gene="srlE"
                     /locus_tag="RHX21_000772"
                     /gene_synonym="gutE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HDV1986000.1"
                     /translation="MTHIRIEKGTGGWGGPLELKATPGKKIVYITAGTRPAIVDKLAQ
                     LTGWQAIDGFKEGEPAEAEIGVAVIDCGGTLRCGIYPKRRIPTINIHSTGKSGPLAQY
                     IVEDIYVSGVKEENITVVGDATPQPSSVGRDYDTSKKITEQSDGLLAKVGMGMGSAVA
                     VLFQSGRDTIDTVLKTILPFMAFVSALIGIIMASGLGDWIAHGLAPLASHPLGLVMLA
                     LICSFPLLSPFLGPGAVIAQVIGVLIGVQIGLGNIPPHLALPALFAINAQAACDFIPV
                     GLSLAEARQDTVRVGVPSVLVSRFLTGAPTVLIAWFVSGFIYQ"
     gene            9501..9872
                     /gene="srlB"
                     /locus_tag="RHX21_000773"
                     /gene_synonym="gutB"
     CDS             9501..9872
                     /gene="srlB"
                     /locus_tag="RHX21_000773"
                     /gene_synonym="gutB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDV1986001.1"
                     /translation="MTVIYQTTITRIGASATDALSDQMLITFREGAPADLEEYCFIHC
                     HGELKGALHPGLQFSLGQHRYPVTAVGSVAEDNLRELGHVTLRFDGLNEAEFPGTVHV
                     AGPVPDDIAPGSVLKFESVKE"
     gene            9876..10655
                     /gene="srlD"
                     /locus_tag="RHX21_000774"
     CDS             9876..10655
                     /gene="srlD"
                     /locus_tag="RHX21_000774"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HDV1986002.1"
                     /translation="MNQVAVVIGGGQTLGAFLCHGLAAEGYRVAVVDIQSDKAANVAQ
                     EINAEYGESMAYGFGADATSEQSVLALSRGVDEIFGRVDLLVYSAGIAKAAFISDFQL
                     GDFDRSLQVNLVGYFLCAREFSRLMIRDGIQGRIIQINSKSGKVGSKHNSGYSAAKFG
                     GVGLTQSLALDLAEYGITVHSLMLGNLLKSPMFQSLLPQYATKLGIKPDQVEQYYIDK
                     VPLKRGCDYQDVLNMLLFYASPKASYCTGQSINVTGGQVMF"
     gene            10760..11119
                     /gene="gutM"
                     /locus_tag="RHX21_000775"
     CDS             10760..11119
                     /gene="gutM"
                     /locus_tag="RHX21_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HDV1986003.1"
                     /translation="MVSALITVAVIAWCAQLALGGWQISRFNRAFDTLCQQGRVGVGR
                     SSGRFKPRVVVAIALDDQQRIVDTLFMKGLTVFARPQKIPAITGMHAGDLQPDVIFPH
                     DPLSQNALSLALKLKRG"
     gene            11186..11959
                     /gene="srlR"
                     /locus_tag="RHX21_000776"
                     /gene_synonym="gutR"
     CDS             11186..11959
                     /gene="srlR"
                     /locus_tag="RHX21_000776"
                     /gene_synonym="gutR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucitol operon DNA-binding transcriptional
                     repressor SrlR"
                     /protein_id="HDV1986004.1"
                     /translation="MKPRQRQAAILEYLQKQGKCSVEELAQYFDTTGTTIRKDLVILE
                     HAGTVIRTYGGVVLNKEESDPPIDHKTLINTHKKELIAEAAVSFIHDGDSIILDAGST
                     VLQMVPLLSRFNNITVMTNSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENA
                     FEHFSFDKLFMGTDGIDLNAGVTTFNEVYTVSKAMCNAAREVILMADSSKFGRKSPNV
                     VCSLESVDKLITDAGIDPAFRQALEEKGIDVIITGESNE"
     gene            11952..12917
                     /gene="gutQ"
                     /locus_tag="RHX21_000777"
     CDS             11952..12917
                     /gene="gutQ"
                     /locus_tag="RHX21_000777"
                     /EC_number="5.3.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311591.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-5-phosphate isomerase GutQ"
                     /protein_id="HDV1986005.1"
                     /translation="MSEALLNAGRQTLMLELQEASRLPERLGDDFVRAANIILHCEGK
                     VVVSGIGKSGHIGKKIAATLASTGTPAFFVHPAEALHGDLGMIESRDVMLFISYSGGA
                     KELDLIIPRLEDKSIALLAMTGKPTSPLGLAAKAVLDISVEREACPMHLAPTSSTVNT
                     LMMGDALAMAVMQARGFNEEDFARSHPAGALGARLLNKVHHLMRRDDAIPQVALTASV
                     MDAMLELSRTGLGLVAVCDAQQQVQGVFTDGDLRRWLVGGGALTTPVNEAMTTGGTTL
                     QAQSRAIDAKEILMKRKITAAPVVDENGKLTGAINLQDFYQAGII"
     gene            complement(12914..14428)
                     /gene="norR"
                     /locus_tag="RHX21_000778"
     CDS             complement(12914..14428)
                     /gene="norR"
                     /locus_tag="RHX21_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311592.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase transcriptional regulator
                     NorR"
                     /protein_id="HDV1986006.1"
                     /translation="MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALL
                     RYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLI
                     PGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNA
                     LLIEQLESQNMMPGDATPFEAVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETG
                     TGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFE
                     MADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDCSLRVDVRVLAATNRDLREE
                     VLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSAGAR
                     NLLQHYRFPGNVRELEHAIHRAVVLARATRSGDEVILEAQHFAFPEVTLPPPEAAAVP
                     VVKQNLREATEAFQRETIRQALAQNHHNWAACARMLETDVANLHRLAKRLGLKD"
     gene            14615..16054
                     /gene="norV"
                     /locus_tag="RHX21_000779"
     CDS             14615..16054
                     /gene="norV"
                     /locus_tag="RHX21_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic nitric oxide reductase
                     flavorubredoxin"
                     /protein_id="HDV1986007.1"
                     /translation="MSIVVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEK
                     NVLIDTVDHKFSREFVQNLRNEIDLADIDYIVINHAEEDHAGALTELMAQIPDTPIYC
                     TANAIDSINGHHHHPEWNFNVVKTGDTLDIGNGKQLIFVETPMLHWPDSMMTYLTGDA
                     VLFSNDAFGQHYCDEHLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNL
                     PVDMIATSHGVVWRDNPTQIVELYLKWAADYQEDRITIFYDTMSNNTRMMADAIAQGI
                     AETDPRVAVKIFNVARSDKNEILTNVFRSKGVLVGTSTMNNVMMPKIAGLVEEMTGLR
                     FRNKRASAFGSHGWSGGAVDRLSTRLQDAGFEMSLSLKAKWRPDQDALELCREHGREI
                     ARQWALAPLPQSTVNTVVKEETSATTTADLGPRMQCSVCQWIYDPAKGEPMQDVAPGT
                     PWSEVPDNFLCPECSLGKDVFDELASEAK"
     gene            16051..17184
                     /gene="norW"
                     /locus_tag="RHX21_000780"
     CDS             16051..17184
                     /gene="norW"
                     /locus_tag="RHX21_000780"
                     /EC_number="1.18.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavorubredoxin reductase NorW"
                     /protein_id="HDV1986008.1"
                     /translation="MSNGIVIIGSGFAARQLVKNIRKQDATIPLTLIAADSMDEYNKP
                     DLSHVISQGQRADDLTRQTAGEFAEQFNLHLFPQTWVTDIDAEARVVKSQNNQWQYDK
                     LVLATGASAFVPPVPGRELMLTLNSQQEYRACETQLRDARRVLIVGGGLIGSELAMDF
                     CRAGKAVTLIDNAASILASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTDSGILA
                     TLDRQRSIEVDAVIAATGLRPETALARRAGLTINRGVCVDSYLQTSNADIYALGDCAE
                     INGQVLPFLQPIQLSAMVLAKNLLGNNTPLKLPAMLVKIKTPELPLHLAGETQRQDLR
                     WQINTERQGMVARGVDDADQLRAFVVSEDRMKEAFGLLKTLPM"
     gene            complement(17410..19662)
                     /gene="hypF"
                     /locus_tag="RHX21_000781"
     CDS             complement(17410..19662)
                     /gene="hypF"
                     /locus_tag="RHX21_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyltransferase HypF"
                     /protein_id="HDV1986009.1"
                     /translation="MAKNTSCGVQLRIRGKVQGVGFRPFVWQLAQQLNLHGDVCNDGD
                     GVEVRLLEDPETFLVQLHQHCPPLARIDSVEREPFIWSQLPTEFTIRQSAGGAMNTQI
                     VPDAATCPACLAEMNTPGERRYRYPFINCTHCGPRFTIIRAMPYDRPFTVMAEFPLCP
                     ACDKEYRDPLDRRFHAQPVACPECGPHLEWVSHGEHAEQEAALQAAIAQLKMGNIVAI
                     KGIGGFHLACDARNSTAVATLRARKHRPAKPLAVILPVAEGLPDAARQLLTTPAAPIV
                     LVDKKYVPELCDDIAPGLNEVGVMLPANPLQHLLLQELQCPLVMTSGNLSGKPPAISN
                     EQALADLQGIADGFLIHNRDIVQRMDDSVVRESGEMLRRSRGYVPDALALPPGFKNVP
                     PVLCLGADLKNTFCLVRGEQAVLSQHLGDLSDDGIQMQWREALRLMQNIYDFTPQYVV
                     HDAHPGYVSSQWAREMNLPTQTVLHHHAHAAACLAEHQWPLDGGDVIALTLDGIGMGE
                     NGALWGGECLRVNYRECEHLGGLPAVALPGGDLAAKQPWRNLLAQCLRFVPEWQNYSE
                     TASVQQQNWSVLARAIERGINAPLASSCGRLFDAVAAALGCAPATLSYEGEAACALEA
                     LAASCHGVTHPVTMPLVDNQLDLATFWQQWLNWQAPVNQRAWAFHDALAQGFAALMRE
                     QATMRGITTLVFSGGVIHNRLLRARLAHYLADFTLLFPQSLPAGDGGLSLGQGVIAAA
                     RWLAGEVQNG"
     gene            complement(19815..20342)
                     /gene="hydN"
                     /locus_tag="RHX21_000782"
     CDS             complement(19815..20342)
                     /gene="hydN"
                     /locus_tag="RHX21_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport protein HydN"
                     /protein_id="HDV1986010.1"
                     /translation="MNRFIIADASKCIGCRTCEVACVVSHQENQDCASLTPETFLPRI
                     HVIKGVNISTATVCRQCEDAPCANVCPNGAISRDKGFVHVMQERCIGCKTCVVACPYG
                     AMEVVVRPVIRNSGAGLNVRADKAEANKCDLCNHREDGPACMAACPTHALICVDRNKL
                     EQLSAEKRRRTALMF"
     gene            complement(20491..21501)
                     /gene="ascG"
                     /locus_tag="RHX21_000783"
     CDS             complement(20491..21501)
                     /gene="ascG"
                     /locus_tag="RHX21_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417194.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator AscG"
                     /protein_id="HDV1986011.1"
                     /translation="MTTMLEVAKRAGVSKATVSRVLSGNGYVSQETKDRVFQAVEESG
                     YRPNLLARNLSAKSTQTLGLVVTNTLYHGIYFSELLFHAARMAEEKGRQLLLADGKHS
                     AEEERQAIQYLLDLRCDAIMIYPRFLSVDEIDDIIDAHSQPIMVLNRRLRKNSSHSVW
                     CDHKQTSFNAVAELINAGHQEIAFLTGSMDSPTSIERLAGYKDALAQHGIALNEKLIA
                     NGKWTPASGAEGVETLLERGAKFSALVASNDDMAIGAMKALHERGVAVPEQVSVIGFD
                     DIAIAPYTVPALSSVKIPVTEMIQEIIGRLIFMLDGGDFSPPKTFSGKLIRRDSLIAL
                     SR"
     gene            21761..23218
                     /gene="ascF"
                     /locus_tag="RHX21_000784"
     CDS             21761..23218
                     /gene="ascF"
                     /locus_tag="RHX21_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose/arbutin/salicin transporter
                     subunit IIBC"
                     /protein_id="HDV1986012.1"
                     /translation="MAKNYAALARSVIAALGGVDNISAVTHCMTRLRFVIKDDQLIDS
                     PTLKTIPGVLGVVRSDNQCQVIIGNTVSQAFQEVVSLLPGDMQPAQPVGKPKLTLRRI
                     GAGILDALIGTMSPLIPAIIGGSMVKLLAMILEMSGVLTKGSPTLTILNVIGDGAFFF
                     LPLMVAASAAIKFKTNMSLAIAIAGVLVHPSFIELMAKAAQGEHVEFALIPVTAVKYT
                     YTVIPALVMTWCLSYIERWVDRITPAVTKNFLKPMLIVLIAAPLAILLIGPIGIWIGS
                     AISALVYTIHGYLGWLSVAIMGALWPLLVMTGMHRVFTPTIIQTIAETGKEGMVMPSE
                     IGANLSLGGSSLAVAWKTKNPELRQTALAAAASAIMAGISEPALYGVAIRLKRPLIAS
                     LISGFICGAVAGMAGLASHSMAAPGLFTSVQFFDPANPMSIVWVFAVMALAVMLSFIL
                     TLLLGFEDIPVEEATAEARKHQSVQPTVAKEVSLN"
     gene            23227..24651
                     /gene="ascB"
                     /locus_tag="RHX21_000785"
     CDS             23227..24651
                     /gene="ascB"
                     /locus_tag="RHX21_000785"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase AscB"
                     /protein_id="HDV1986013.1"
                     /translation="MSVFPEGFLWGGALAANQSEGAFREGGKGLTTVDMIPHGEHRMA
                     VKLGLEKRFQLRDDEFYPSHEATDFYHRYKEDIALMAEMGFKVFRTSIAWSRLFPQGD
                     EITPNQQGIAFYRSVFEECKKYGIEPLVTLCHFDVPMHLVTEYGSWRNRKLVEFFSRY
                     ARTCFEAFDGLVKYWLTFNEINIMLHSPFSGAGLVFEEGENQDQVKYQAAHHQLVASA
                     LATKIAHEVNPQNQVGCMLAGGNFYPYSCKPEDVWAALEKDRENLFFIDVQARGAYPA
                     YSARVFREKGVTIDKAPGDDEILKNTVDFVSFSYYASRCASAEMNANNSSAANVVKSL
                     RNPYLQVSDWGWGIDPLGLRITMNMMYDRYQKPLFLVENGLGAKDELAANGEINDDYR
                     ISYLREHIRAMGEAIADGIPLMGYTTWGCIDLVSASTGEMSKRYGFVFVDRDDAGNGT
                     LTRTRKKSFWWYKKVIASNGEDLE"
     gene            complement(24810..25280)
                     /gene="hycI"
                     /locus_tag="RHX21_000786"
     CDS             complement(24810..25280)
                     /gene="hycI"
                     /locus_tag="RHX21_000786"
                     /EC_number="3.4.23.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation peptidase HycI"
                     /protein_id="HDV1986014.1"
                     /translation="MTDVLLCVGNSMMGDDGAGPLLAEKCAAAPKGNWVVIDGGSAPE
                     NDIVAIRELRPTRLLIVDATDMGLNPGEIRIIDPDDIAEMFMMTTHNMPLNYLIDQLK
                     EDIGEVIFLGIQPDIVGFYYPMTQPIKDAVETVYQRLEGWEGNGGFAQLAVEEE"
     gene            complement(25273..25683)
                     /gene="hycH"
                     /locus_tag="RHX21_000787"
     CDS             complement(25273..25683)
                     /gene="hycH"
                     /locus_tag="RHX21_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase assembly protein HycH"
                     /protein_id="HDV1986015.1"
                     /translation="MSEKVVFSQLSRKFIDENDATPAEAQQVVYYSLAIGHHLGVIDC
                     LEAALTCPWDEYLAWIATLEAGSEARRKMEGVPKYGEIVIDINHVPMLANAFDKARAA
                     QTSQQQEWSTMLLSMLHDIHQENAIYLMVRRLRD"
     gene            complement(25680..26447)
                     /gene="hycG"
                     /locus_tag="RHX21_000788"
     CDS             complement(25680..26447)
                     /gene="hycG"
                     /locus_tag="RHX21_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycG"
                     /protein_id="HDV1986016.1"
                     /translation="MSNLLGPRDANGIPVPMTVDESIASMKASLLKKIKRSAYVYRVD
                     CGGCNGCEIEIFATLSPLFDAERFGIKVVPSPRHADILLFTGAVTRAMRSPALRAWQS
                     APDPKICISYGACGNSGGIFHDLYCVWGGTDKIIPVDVYIPGCPPTPAATLYGFAMAL
                     GLLEQKIHARGPGEQDEQPAEILHGDMVQPLRVKVDREARRLAGYRYGRQIADDFLTQ
                     LGQGEEQVARWLEAENDPRLNEIVSHLNHVVEEARIR"
     gene            complement(26447..26989)
                     /gene="hycF"
                     /locus_tag="RHX21_000789"
     CDS             complement(26447..26989)
                     /gene="hycF"
                     /locus_tag="RHX21_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycF"
                     /protein_id="HDV1986017.1"
                     /translation="MFTFIKKVIKTGTATSSYPLEPIAVDKNFRGKPEQNPQQCIGCA
                     ACVNACPSNALTVETDLATGELAWEFNLGRCIFCGRCEEVCPTAAIKLSQEYELAVWK
                     KEDFLQQSRFVLCSCRVCNRPFAVQKEIDYAIALLKHNGDSRAENHRESFETCPECKR
                     QKCLVPSDRIELTRHMKEAI"
     gene            complement(26999..28708)
                     /gene="hycE"
                     /locus_tag="RHX21_000790"
     CDS             complement(26999..28708)
                     /gene="hycE"
                     /locus_tag="RHX21_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycE"
                     /protein_id="HDV1986018.1"
                     /translation="MSEEKLGQHYLAALNEAFPGVVLDHAWQTKDQLTVTVKVNYLPE
                     VVEFLYYKQGGWLSVLFGNDERKLNGHYAVYYVLSMEKGTKCWVTVRVEVDANKPEYP
                     SVTPRVPAAVWGEREVRDMYGLIPVGLPDERRLVLPDDWPDELYPLRKDSMDYRQRPA
                     PTTDAETYEFINELGDKKNNVVPIGPLHVTSDEPGHFRLFVDGENIIDADYRLFYVHR
                     GMEKLAETRMGYNEVTFLSDRVCGICGFAHSTAYTTSVENAMGIQVPERAQMIRAILL
                     EVERLHSHLLNLGLACHFTGFDSGFMQFFRVRETSMKMAEILTGARKTYGLNLIGGIR
                     RDLLKDDMIQTRQLAQQMRREVQELVDVLLSTPNMEQRTVGIGRLDPEIARDFSNVGP
                     MVRASGHARDTRADHPFVGYGLLPMEVHSEQGCDVISRLKVRINEVYTALNMIDYGLD
                     NLPGGPLMVEGFTYIPHRFALGFAEAPRGDDIHWSMTGDNQKLYRWRCRAATYANWPT
                     LRYMLRGNTVSDAPLIIGSLDPCYSCTDRMTVVDVRKKKSKVVPYKELERYSIERKNS
                     PLK"
     gene            complement(28726..29649)
                     /gene="hycD"
                     /locus_tag="RHX21_000791"
     CDS             complement(28726..29649)
                     /gene="hycD"
                     /locus_tag="RHX21_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycD"
                     /protein_id="HDV1986019.1"
                     /translation="MSVLYPLIQALVLFAVAPLLSGITRVARARLHNRRGPGVLQEYR
                     DIFKLLGRQSVGPDASGWVFRLTPYVMVGVMLTIATALPVVTVGSPLPQLGDLITLLY
                     LFAIARFFFAISGLDTGSPFTAIGASREAMLGVLVEPMLLLGLWVAAQVAGSTNISNI
                     TDTVYHWPLSQSIPLVLALCACAFATFIEMGKLPFDLAEAEQELQEGPLSEYSGSGFG
                     VMKWGISLKQLVVLQMFVGVFIPWGQMETFTAGGLLLALVIAIVKLVVGVLVIALFEN
                     SMARLRLDITLRITWAGFGFAFLAFVSLLAA"
     gene            complement(29652..31478)
                     /gene="hycC"
                     /locus_tag="RHX21_000792"
     CDS             complement(29652..31478)
                     /gene="hycC"
                     /locus_tag="RHX21_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit 3"
                     /protein_id="HDV1986020.1"
                     /translation="MSAISLINSGVAWFVAAAVLAFLFSFQKALSGWIAGIGGAVGSL
                     YTAAAGFTVLTGAVGVSGALSLVSYDVQISPLNAIWLITLGLCGLFVSLYNIDWHRHA
                     QVKCNGLQINMLMAAAVCAVIASNLGMFVVMAEVMALCAVFLTSNSKEGKLWFALGRL
                     GTLLLAIACWLLWQRYGTLDLRLLDMRMQQLPLGSDIWLLGVIGFGLLAGIIPLHGWV
                     PQAHANASAPAAALFSTVVMKIGLLGMLTLSLLGGNAPLWWGIALLVLGMITAFVGGL
                     YALMEHNIQRLLAYHTLENIGIILLGLGAGVTGIALEQPALIALGLVGGLYHLLNHSL
                     FKSVLFLGAGSVWFRTGHRDIEKLGGIGKKMPVISIAMLVGLMAMAALPPLNGFAGEW
                     VIYQSFFKLSNSGAFVARLLGPLLAVGLAITGALAVMCMAKVYGVTFLGAPRTKEAEN
                     ATCAPLLMSVSVVALAICCVIGGVAAPWLLPMLSAAVPLPLEPANTTVSQPMITLLLI
                     ACPLLPFIIMAICKGDRLPSRSRGAAWVCGYDHEKSMVITAHGFAMPVKQAFAPVLKL
                     RKWLNPVSLVPGWQCEGSALLFRRMALVELAVLVVIIVSRGA"
     gene            complement(31475..32086)
                     /gene="hycB"
                     /locus_tag="RHX21_000793"
     CDS             complement(31475..32086)
                     /gene="hycB"
                     /locus_tag="RHX21_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycB"
                     /protein_id="HDV1986021.1"
                     /translation="MNRFVIADSTLCIGCHTCEAACSETHRQHGLQSMPRLRVMLNEK
                     ESAPQLCHHCEDAPCAVVCPVNAITRVDGAVQLNESLCVSCKLCGIACPFGAIEFSGS
                     RPLDIPANANTPKAPPAPPAPARISTLLDWVPGIRAIAVKCDLCSFDEQGPACVRMCP
                     TKALHLVDNTDIARVSKRKRELTFNTDFGDLTLFQQAQSGEAK"
     gene            complement(32211..32672)
                     /gene="hycA"
                     /locus_tag="RHX21_000794"
     CDS             complement(32211..32672)
                     /gene="hycA"
                     /locus_tag="RHX21_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase regulator HycA"
                     /protein_id="HDV1986022.1"
                     /translation="MTIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKARLHH
                     AMSCAPDKELCFVLFEHFRIYVTLADGFNSHTIEYYVETKDGEDKQRIAQAQLSIDGM
                     IDGKVNIRDREQVLEHYLEKIAGVYDSLYTAIENNVPVNLSQLVKGQSPAA"
     gene            32884..33234
                     /gene="hypA"
                     /locus_tag="RHX21_000795"
     CDS             32884..33234
                     /gene="hypA"
                     /locus_tag="RHX21_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HDV1986023.1"
                     /translation="MHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSL
                     AFCFDLVCRGSVAEGCKLHLEEQEAECWCETCQQYVTLLTQRVRRCPQCHGDMLQIVA
                     DDGLQIRRIEIDQE"
     gene            33238..34110
                     /gene="hypB"
                     /locus_tag="RHX21_000796"
     CDS             33238..34110
                     /gene="hypB"
                     /locus_tag="RHX21_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase nickel incorporation protein HypB"
                     /protein_id="HDV1986024.1"
                     /translation="MCTTCGCGEGNLYIEGDEHNPHSAFRSAPFAPAARPKMKITGIK
                     APEFTPSQTEEGDLHYGHGEAGTHAPGMSQRRMLEVEIDVLDKNNRLAERNRARFAAR
                     KQLVLNLVSSPGSGKTTLLTETLMRLKDSVPCAVIEGDQQTVNDAARIRATGTPAIQV
                     NTGKGCHLDAQMIADAAPRLPLDDNGILFIENVGNLVCPASFDLGEKHKVAVLSVTEG
                     EDKPLKYPHMFAAASLMLLNKVDLLPYLNFDVEKCIACAREVNPEIEIILISATSGEG
                     MDQWLNWLETQRCA"
     gene            34101..34373
                     /gene="hypC"
                     /locus_tag="RHX21_000797"
     CDS             34101..34373
                     /gene="hypC"
                     /locus_tag="RHX21_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 3 maturation protein HypC"
                     /protein_id="HDV1986025.1"
                     /translation="MCIGVPGQIRTIDGNQAKVDVCGIQRDVDLTLVGSCDKNGQPRV
                     GQWVLVHVGFAMSVINEAEARDTLDALQNMFDVEPDVGALLYGEEK"
     gene            34373..35494
                     /gene="hypD"
                     /locus_tag="RHX21_000798"
     CDS             34373..35494
                     /gene="hypD"
                     /locus_tag="RHX21_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase formation protein HypD"
                     /protein_id="HDV1986026.1"
                     /translation="MRFVDEYRAPEQVMQLIEHLRERASHLSYTAERPLRIMEVCGGH
                     THAIFKFGLDQLLPENVEFIHGPGCPVCVLPMGRIDTCVEIASHPEVIFCTFGDAMRV
                     PGKQGSLLQAKARGADVRIVYSPMDALKLAQENPTRKVVFFGLGFETTMPTTAITLQQ
                     AKARDVQNFYFFCQHITLIPTLRSLLEQPDNGIDAFLAPGHVSMVIGTDAYNFIASDF
                     HRPLVVAGFEPLDLLQGVVMLVEQKIAAHSKVENQYRRVVPDAGNLLAQQAIADVFCV
                     NGDSEWRGLGVIESSGVHLTPDYQRFDAEAHFRPAPQQVCDDPRARCGEVLTGKCKPH
                     QCPLFGNTCNPQTAFGALMVSSEGACAAWYQYRQQESEA"
     gene            35491..36501
                     /gene="hypE"
                     /locus_tag="RHX21_000799"
     CDS             35491..36501
                     /gene="hypE"
                     /locus_tag="RHX21_000799"
                     /EC_number="4.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311613.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation carbamoyl dehydratase
                     HypE"
                     /protein_id="HDV1986027.1"
                     /translation="MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLA
                     QLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEE
                     GLPMETLKAVVTSMAETARTAGIAIVTGDTKVVQRGAADKLFINTAGMGAIPANIHWG
                     AQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPGVKA
                     LRDATRGGVNAVVHEFAAACGCGIEISESALPVKPAVRGVCELLGLDALNFANEGKLV
                     IAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR
                     IC"
     gene            36575..38653
                     /gene="flhA"
                     /locus_tag="RHX21_000800"
     CDS             36575..38653
                     /gene="flhA"
                     /locus_tag="RHX21_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase transcriptional activator
                     FlhA"
                     /protein_id="HDV1986028.1"
                     /translation="MSYTPMSDLGQQGLFDITRTLLQQPDLASLCEALSQLVKRSALA
                     DNAAIVLWQAQTQRASYYASREKDTPIKYEDETVLAHGPVRSILSRPDTLHCSYEEFC
                     ETWPQLAAGGLYPKFGHYCLMPLAAEGHIFGGCEFIRYDDRPWSEKEFNRLQTFTQIV
                     SVVTEQIQSRVVNNVDYELLCRERDNFRILVAITNAVLSRLDMDELVSEVAKEIHYYF
                     DIDDISIVLRSHRKNKLNIYSTHYLDKQHPAHEQSEVDEAGTLTERVFKSKEMLLINL
                     HERDDLAPYERMLFDTWGNQIQTLCLLPLMSGDTMLGVLKLAQCEEKVFTTTNLNLLR
                     QIAERVAIAVDNALAYQEIHRLKERLVDENLALTEQLNNVDSEFGEIIGRSEAMYSVL
                     KQVEMVAQSDSTVLILGETGTGKELIARAIHNLSGRNNRRMVKMNCAAMPAGLLESDL
                     FGHERGAFTGASAQRIGRFELADKSSLFLDEVGDMPLELQPKLLRVLQEQEFERLGSN
                     KIIQTDVRLIAATNRDLKKMVADREFRSDLYYRLNVFPIHLPPLRERPEDIPLLAKAF
                     TFKIARRLGRNIDSIPAETLRTLSNMEWPGNVRELENVIERAVLLTRGNVLQLSLPDI
                     VLPEPETPPAATVVAQEGEDEYQLIVRVLKETNGVVAGPKGAAQRLGLKRTTLLSRMK
                     RLGIDKSALI"
     gene            complement(38690..39043)
                     /locus_tag="RHX21_000801"
     CDS             complement(38690..39043)
                     /locus_tag="RHX21_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrous oxide-stimulated promoter family
                     protein"
                     /protein_id="HDV1986029.1"
                     /translation="MSGKRISREKLTIKKMIDLYQAKCPQASAEPEHYEALFVYAQKR
                     LDKCVFGEEKPACKQCPVHCYQPAKREEMKQIMRWAGPRMLWRHPILTVRHLIDDKRP
                     VPELPEKYRPKKPRE"
     gene            complement(39075..39254)
                     /locus_tag="RHX21_000802"
     CDS             complement(39075..39254)
                     /locus_tag="RHX21_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001363568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986030.1"
                     /translation="MIPELIISGEEANGEFLMLVPGKMLFCSFCVMLMKQVRKIASVG
                     EPFFFRVIVPFKIKM"
     gene            39330..41891
                     /gene="mutS"
                     /locus_tag="RHX21_000803"
     CDS             39330..41891
                     /gene="mutS"
                     /locus_tag="RHX21_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDV1986031.1"
                     /translation="MSAIENFDAHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYDDA
                     KRASQLLDISLTKRGASAGEPIPMAGIPYHAVENYLAKLVNQGESVAICEQIGDPATS
                     KGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEP
                     ADRETMAAELQRTNPAELLYAEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFG
                     TRDLVGFGVENAPRGLCAAGCLLQYAKDTQRTTLPHIRSITMEREQDSIIMDAATRRN
                     LEITQNLAGGAENTLASVLDCTVTPMGSRMLKRWLHMPVRDTRVLLERQQTIGALQDF
                     TAELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELRAQLETVDSAPVQA
                     LREKMGEFAELRDLLERAIIDTPPVLVRDGGVIASGYNEELDEWRALADGATDYLERL
                     EVRERERTGLDTLKVGFNAVHGYYIQISRGQSHLAPINYMRRQTLKNAERYIIPELKE
                     YEDKVLTSKGKALALEKQLYEELFDLLLPHLEALQQSASALAELDVLVNLAERAYTLN
                     YTCPTFIDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYM
                     RQTALIALMAYIGSYVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILH
                     NATEYSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKME
                     GVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELES
                     ISPNAAATQVDGTQMSLLSVPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV"
     gene            41997..42653
                     /gene="pphB"
                     /locus_tag="RHX21_000804"
     CDS             41997..42653
                     /gene="pphB"
                     /locus_tag="RHX21_000804"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase"
                     /protein_id="HDV1986032.1"
                     /translation="MPSTRYQKINAHHYRHIWVVGDIHGEYQLLQSRLHQLSFFPETD
                     LLISVGDNIDRGPESLDVLRLLNQPWFISVKGNHEAMALDAFATGDGNMWLASGGDWF
                     FDLNDSEQKEATDLLLKFHHLPHIIEITNDNIKYVIAHADYPGSEYLFGKEIAESELL
                     WPVDRVQKSLNGELQQINGADYFIFGHMMFDNIQTFANQIYIDTGSPKSGRLSFYKIR
                     "
     gene            complement(42704..43471)
                     /locus_tag="RHX21_000805"
     CDS             complement(42704..43471)
                     /locus_tag="RHX21_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417215.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDV1986033.1"
                     /translation="MIPVERRQIILEMVAEKGIVSIAELTDRMNVSHMTIRRDLQKLE
                     QQGAVVLVSGGVQSPGRVAHEPSHQVKTALAMTQKAAIGKLAASLVQPGSCIYLDAGT
                     TTLAIAQHLIHMESLTVVTNDFVIANYLLDNSNCTIIHTGGAVCRENRSCVGEAAATM
                     LRSLMIDQAFISASSWSVRGISTPAEDKVTVKRAIASASRQRVLVCDATKYGQVATWL
                     ALPLSEFDQIITDDGLPESASRALAKQDLSLLVAKNE"
     gene            43667..44575
                     /locus_tag="RHX21_000806"
     CDS             43667..44575
                     /locus_tag="RHX21_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDV1986034.1"
                     /translation="MKTGSEFHVGIVGLGSMGMGAALSCVRAGLSTWGADLNSNACAT
                     LKEAGACGVSDNAATFAEKLDALLVLVVNAAQVKQVLFGETGVAQHLKPGTAVMVSST
                     IASADAQEIATALAGFDLEMLDAPVSGGAVKAANGEMTVMASGSDIAFERLAPVLEAV
                     AGKVYRIGAEPGLGSTVKIIHQLLAGVHIAAGAEAMALAARAGIPLDVMYDVVTNAAG
                     NSWMFENRMRHVVDGDYTPHSAVDIFVKDLGLVADTAKALHFPLPLASTALNMFTSAS
                     NAGYGKEDDSAVIKIFSGITLPGAKS"
     gene            44572..45834
                     /locus_tag="RHX21_000807"
     CDS             44572..45834
                     /locus_tag="RHX21_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001649192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxo-tetronate kinase"
                     /protein_id="HDV1986035.1"
                     /translation="MIKIGVIADDFTGATDIASFLVENGLPTVQINGVPTGKMPEAID
                     ALVISLKTRSCPVVEATQQSLAALSWLQQQGCKQIYFKYCSTFDSTAKGNIGPVTDAL
                     MDALDTPFTVFSPALPVNGRTVYQGYLFVMNQLLAESGMRHHPVNPMTDSYLPRLVEA
                     QSTGRCGVVSAHVFEQGVDAVRQELARLQQEGYRYAVLDALTEHHLEIQGEALRDAPL
                     VTGGSGLAIGLARQWAQENGNQAREAGHPLAGRGVVLSGSCSQMTNRQVAHYRQIAPA
                     REVDVARCLSTETLAAYAHELAEWVLGQESVLAPLVFATASTDALAAIQQQYGAQKAS
                     QAVETLFSQLAARLAAEGVTRFIVAGGETSGVVTQSLGIKGFHIGPTISPGVPWVNAL
                     DKPVSLALKSGNFGDEAFFSRAQREFLS"
     gene            45831..46469
                     /locus_tag="RHX21_000808"
     CDS             45831..46469
                     /locus_tag="RHX21_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HDV1986036.1"
                     /translation="MSDFAKVEQSLREEMTRIASSFFQRGYATGSAGNLSLLLPDGNL
                     LATPTGSCLGNLDPQRLSKVAADGEWLSGDKPSKEVLFHLALYRNNPRCKAVVHLHST
                     WSTALSCLQGLDSSNVIRPFTPYVVMRMGNVPLVPYYRPGDKRIAQDLAELAADNQAF
                     LLANHGPVVCGESLQEAANNMEELEETAKLIFILGDRPIRYLTAGEIAELRS"
     gene            46474..47250
                     /locus_tag="RHX21_000809"
     CDS             46474..47250
                     /locus_tag="RHX21_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr family phosphocarrier protein"
                     /protein_id="HDV1986037.1"
                     /translation="MPRFAANLSMMFTEVPFIERFAAARKAGFDAVEFLFPYDYSTLQ
                     IQKQLEQNHLTLALFNTAPGDINAGEWGLSALPGREHEAHADIDLALEYALALNCEQV
                     HVMAGVVPAGEDAERYRAVFIDNLRYAADRFALHGKRILVEALSPDVKPHYLFSSQYQ
                     ALAIVEEVARDNVFIQLDTFHAQKVDGNLTHLIRDYAGKYAHVQIAGLPDRHEPDDGE
                     INYPWLFRLFDEVGYQGWIGCEYKPRGLTEEGLGWFDAWR"
     gene            47339..48703
                     /locus_tag="RHX21_000810"
     CDS             47339..48703
                     /locus_tag="RHX21_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family transporter"
                     /protein_id="HDV1986038.1"
                     /translation="MSTITLLCIALAGVIMLLLLVIKAKVQPFVALLLVSLLVALAAG
                     IPAGEVGKVMIAGMGGVLGSVTIIIGLGAMLGRMIEHSGGAESLANYFSRKLGDKRTI
                     AALTLAAFFLGIPVFFDVGFIILAPIIYGFAKVAKISPLKFGLPVAGIMLTVHVAVPP
                     HPGPVAAAGLLHADIGWLTIIGIAISIPVGIVGYFAAKIINTRQYAMSVEVLEQMQLA
                     PASEEGATKLSDKINPPGVALVTSLIVIPIAIIMAGTVSATLMPPSHPLLGTLQLIGS
                     PMVALMIALVLAFWLLALRRGWSLQHTSDIMGSALPTAAVVILVTGAGGVFGKVLVES
                     GVGKALANMLQMIDLPLLPAAFIISLALRASQGSATVAILTTGGLLSEAVMGLNPIQC
                     VLVTLAACFGGLGASHINDSGFWIVTKYLGLSVADGLKTWTVLTTILGFTGFLITWCV
                     WAVI"
     gene            complement(48742..48978)
                     /locus_tag="RHX21_000811"
     CDS             complement(48742..48978)
                     /locus_tag="RHX21_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986039.1"
                     /translation="MICPRCADEQIEVMAKSPVKDVWTVYQCQHCLYTWRDTEPLRRT
                     SREHYPEAFRMTQKDIDDAPMVPSIPPLLVEGKR"
     gene            complement(48989..50416)
                     /locus_tag="RHX21_000812"
     CDS             complement(48989..50416)
                     /locus_tag="RHX21_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HDV1986040.1"
                     /translation="MAFDDLRSFLQALDDHGQLLKISEEVNAEPDLAAAANATGRIGD
                     GAPALWFDNIRGFTDARVTMNTIGSWQNHAISLGLPPNTPVKKQIDEFIRRWDNFPIA
                     PERRANPAWAQNTVDGEEINLFDILPLFRLNDGDGGFYLDKACVVSRDPLDPDNFGKQ
                     NVGIYRMEVKGKRKLGLQPVPMHDIALHLHKAEERGEDLPIAITLGNDPIITLMGATP
                     LKYDQSEYEMAGALRESPYPIATAPLTGFDVPWGSEVILEGVIESRKREIEGPFGEFT
                     GHYSGGRNMTVVRIDKVSYRTRPIFESLYLGMPWTEIDYLMGPATCVPLYQQLKAEFP
                     EVQAVNAMYTHGLLAIISTKKRYGGFARAVGLRAMTTPHGLGYVKMVIMVDEDVDPFN
                     LPQVMWALSSKVNPAGDLVQLPNMSVLELDPGSSPAGITDKLIIDATTPVAPDNRGHY
                     SQPVVDLPETKAWAEKLTAMLAARK"
     gene            complement(50416..51009)
                     /locus_tag="RHX21_000813"
     CDS             complement(50416..51009)
                     /locus_tag="RHX21_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HDV1986041.1"
                     /translation="MKLIVGMTGATGAPLGVALLQALRDMPNVETHLVMSKWAKTTIE
                     LETPYSAHDVAALADFSHNPADQAAIISSGSFRTDGMIVIPCSMKTLAGIRAGYADGL
                     VGRAADVVLKEGRKLVLVPREMPLSTIHLENMLALSRMGVAMVPPMPAFYNHPETVDD
                     IVHHVVARVLDQFGLEHPHARRWQGLPQARNFSQENE"
     gene            51156..51563
                     /locus_tag="RHX21_000814"
     CDS             51156..51563
                     /locus_tag="RHX21_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001208089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDV1986042.1"
                     /translation="MALRNKAFHQLRQLFQQHTARWQHELPDLTKPQYAVMRAIADKP
                     GIEQVALIEAAVSTKATLAEMLARMENRGLVRREHDPADKRRRFVWLTAEGEKILAAA
                     IPIGDSVDEEFLGRLSGEEQELFMQLVRKMMNA"
     gene            complement(51684..52676)
                     /gene="rpoS"
                     /locus_tag="RHX21_000815"
     CDS             complement(51684..52676)
                     /gene="rpoS"
                     /locus_tag="RHX21_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoS"
                     /protein_id="HDV1986043.1"
                     /translation="MSQNTLKVHDLNEDAEFDENGVEVFDEKALVEEEPSDNDLAEEE
                     LLSQGATQRVLDATQLYLGEIGYSPLLTAEEEVYFARRALRGDVASRRRMIESNLRLV
                     VKIARRYGNRGLALLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMN
                     QTRTIRLPIHIVKELNVYLRTARELSHKLDHEPSAEEIAEQLDKPVDDVSRMLRLNER
                     ITSVDTPLGGDSEKALLDILADEKENGPEDTTQDDDMKQSIVKWLFELNAKQREVLAR
                     RFGLLGYEAATLEDVGREIGLTRERVRQIQVEGLRRLREILQTQGLNIEALFRE"
     gene            complement(52739..53887)
                     /gene="nlpD"
                     /locus_tag="RHX21_000816"
     CDS             complement(52739..53887)
                     /gene="nlpD"
                     /locus_tag="RHX21_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein hydrolase activator NlpD"
                     /protein_id="HDV1986044.1"
                     /translation="MSAGSPKFTVRRIAALSLVSLWLAGCSDTSNPPAPVSSVNGNAP
                     ANTNSGMLITPPPKMGTTSTAQQPQIQPVQQPQIQATQQPQIQPVQPVQPVAQQPVQM
                     ENGRIVYNRQYGNIPKGSYSGSTYTVKKGDTLFYIAWITGNDFRDLAQRNNIQAPYAL
                     NVGQTLQVGNASGTPITGGNAITQADAAEQGVVIKPAQNSTVAVASQPTITYSESSGE
                     QSANKMLPNNKPTATTVTAPVTVPTASTTEPTVSSTSTSTPISTWRWPTEGKVIETFG
                     ASEGGNKGIDIAGSKGQAIIATADGRVVYAGNALRGYGNLIIIKHNDDYLSAYAHNDT
                     MLVREQQEVKAGQKIATMGSTGTSSTRLHFEIRYKGKSVNPLRYLPQR"
     gene            complement(54027..54653)
                     /gene="pcm"
                     /locus_tag="RHX21_000817"
     CDS             complement(54027..54653)
                     /gene="pcm"
                     /locus_tag="RHX21_000817"
                     /EC_number="2.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-L-isoaspartate O-methyltransferase"
                     /protein_id="HDV1986045.1"
                     /translation="MVSRRVQALLDQLRAQGIQDEQVLNALAAVPREKFVDEAFEQKA
                     WDNIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQHVCS
                     VERIKGLQWQARRRLKNLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMT
                     QLDEGGILVLPVGEEHQYLKRVRRRGGEFIIDTVEAVRFVPLVKGELA"
     gene            complement(54647..55408)
                     /gene="surE"
                     /locus_tag="RHX21_000818"
     CDS             complement(54647..55408)
                     /gene="surE"
                     /locus_tag="RHX21_000818"
                     /EC_number="3.1.3.5"
                     /EC_number="3.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'/3'-nucleotidase SurE"
                     /protein_id="HDV1986046.1"
                     /translation="MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNS
                     LTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVI
                     YSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINV
                     PDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVD
                     EGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW"
     gene            complement(55389..56438)
                     /gene="truD"
                     /locus_tag="RHX21_000819"
     CDS             complement(55389..56438)
                     /gene="truD"
                     /locus_tag="RHX21_000819"
                     /EC_number="5.4.99.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(13) synthase TruD"
                     /protein_id="HDV1986047.1"
                     /translation="MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHI
                     LVRILKNGCNTRFVADALAKFLKIHAREVSFAGQKDKHAVTEQWLCARVPGKEMPDLS
                     AFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYF
                     GAQRFGIGGSNLQGAQRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQ
                     VVDGDALQLAGRGSWFVATTEELAELQRRVNDKELMITAALPGSGEWGTQREALAFEQ
                     AAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVV
                     RELINTTGDYAHIAE"
     gene            complement(56435..56914)
                     /gene="ispF"
                     /locus_tag="RHX21_000820"
     CDS             complement(56435..56914)
                     /gene="ispF"
                     /locus_tag="RHX21_000820"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HDV1986048.1"
                     /translation="MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHAL
                     TDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQA
                     PKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK"
     gene            complement(56914..57624)
                     /gene="ispD"
                     /locus_tag="RHX21_000821"
     CDS             complement(56914..57624)
                     /gene="ispD"
                     /locus_tag="RHX21_000821"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HDV1986049.1"
                     /translation="MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHA
                     LLAHPRVKRVVIAISPGDSRFAQIPLANHPQITVVDGGDERADSVLAGLKAAGDAQWV
                     LVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGL
                     WHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPE
                     DLALAEFYLTRTIHQENT"
     gene            complement(57643..57954)
                     /gene="ftsB"
                     /locus_tag="RHX21_000822"
     CDS             complement(57643..57954)
                     /gene="ftsB"
                     /locus_tag="RHX21_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsB"
                     /protein_id="HDV1986050.1"
                     /translation="MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNA
                     KLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNN
                     R"
     gene            complement(58148..58471)
                     /locus_tag="RHX21_000823"
     CDS             complement(58148..58471)
                     /locus_tag="RHX21_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3561 family protein"
                     /protein_id="HDV1986051.1"
                     /translation="MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPML
                     IYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALF
                     MWLLG"
     gene            complement(58521..59126)
                     /gene="cysC"
                     /locus_tag="RHX21_000824"
     CDS             complement(58521..59126)
                     /gene="cysC"
                     /locus_tag="RHX21_000824"
                     /EC_number="2.7.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyl-sulfate kinase"
                     /protein_id="HDV1986052.1"
                     /translation="MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTV
                     AGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLV
                     VLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFT
                     GIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS"
     gene            complement(59126..60553)
                     /gene="cysN"
                     /locus_tag="RHX21_000825"
     CDS             complement(59126..60553)
                     /gene="cysN"
                     /locus_tag="RHX21_000825"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysN"
                     /protein_id="HDV1986053.1"
                     /translation="MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLI
                     GRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYF
                     STEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGI
                     KHLVVAINKMDLVDYSEETFTRIREDYLTFAEQLPGNLDIRFVPLSALEGDNVASQSE
                     SMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQ
                     RVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAV
                     QSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARIDGIRYQVDINNLTQREVENLPLNG
                     IGLVDLTFDEPLVLDRYQQNPVTGGLIFIDRLSNVTVGAGMVHEPVSQATAAPSEFSA
                     FELELNALVRRHFPHWGARDLLGDK"
     gene            complement(60555..61463)
                     /gene="cysD"
                     /locus_tag="RHX21_000826"
     CDS             complement(60555..61463)
                     /gene="cysD"
                     /locus_tag="RHX21_000826"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="HDV1986054.1"
                     /translation="MDQIRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVML
                     HLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINP
                     FVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRVHRWDP
                     KNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLE
                     RDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVST
                     TSERQGRVIDRDQAGSMELKKRQGYF"
     gene            61715..62752
                     /gene="iap"
                     /locus_tag="RHX21_000827"
     CDS             61715..62752
                     /gene="iap"
                     /locus_tag="RHX21_000827"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase isozyme conversion
                     aminopeptidase"
                     /protein_id="HDV1986055.1"
                     /translation="MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFF
                     PGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTASDNRKSWHNVTGSTVIA
                     AHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKN
                     TPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGV
                     KTPEAVRKLTRDRALAIARSQGIAATTNPGLNKNYPKGTGCCNDAEIFDKAGIAVLSV
                     EATNWNLGNKDGYQQRAKTAAFPAGNSWHDVRFDNQQHIDKALPGRIERRCRDVMRIM
                     LPLVKELAKAS"
     repeat_region   62835..63596
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=62835..62863
                     /rpt_unit_seq="cggtttatccccgctggcgcggggaacac"
     gene            complement(63693..63986)
                     /gene="cas2"
                     /locus_tag="RHX21_000828"
     CDS             complement(63693..63986)
                     /gene="cas2"
                     /locus_tag="RHX21_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated endoribonuclease
                     Cas2"
                     /protein_id="HDV1986056.1"
                     /translation="MSMVVVVTENVPPRLRGRLAIWLLEVRAGVYVGDTSKRIREMIW
                     QQITQLAGCGNVVMAWATNTESGFEFQTWGENRRIPVDLDGLRLVSFLPVDNQ"
     gene            complement(63983..64906)
                     /gene="cas1e"
                     /locus_tag="RHX21_000829"
     CDS             complement(63983..64906)
                     /gene="cas1e"
                     /locus_tag="RHX21_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated endonuclease Cas1"
                     /protein_id="HDV1986057.1"
                     /translation="MTFVPLSPIPLKDRTSMIFLQYGQIDVLDGAFVLIDKTGIRTHI
                     PVGSVACIMLEPGTRVSHAAVHLAATVGTLLVWVGEAGVRVYSSGQPGGARADKLLYQ
                     AKLALTEDLRLKVVRKMYELRFREPPPARRSVDQLRGIEGSRVRQTYALLAKQYGVKW
                     NGRKYDPKDWEKGDVVNRCISAATSCLYGISEAAVLAAGYAPTIGFIHSGKPLSFVYD
                     IADIIKFDSVVPKAFEIAARQPAEPDKEVRLACRDIFRSTKLTGKLIPLIEEVLAAGE
                     IEPPQPAPDMLPPAIPEPETLGDSGHRGRGG"
     gene            complement(64903..65553)
                     /gene="cas6e"
                     /locus_tag="RHX21_000830"
     CDS             complement(64903..65553)
                     /gene="cas6e"
                     /locus_tag="RHX21_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein
                     Cas6/Cse3/CasE"
                     /protein_id="HDV1986058.1"
                     /translation="MYLSRITLHTAQLLPAQLLHLVDRGEYVMHQWLWDLFPGGKERQ
                     FLYRREELQGAFRFFVLSQERPAESETFTIECRSFAPELRTGQSLCFNLRANPTICKA
                     GKRHDLLMEAKRQVRGQAEGRDVWLHQQQAALDWLAAQGERSGFTLLDTSVDAYRQQQ
                     LRRENSRQLIQFSSVDYTGMLTVTDPGLFLQRLSQGYGKSRAFGCGLMLIKPGAEA"
     gene            complement(65535..66281)
                     /gene="cas5e"
                     /locus_tag="RHX21_000831"
     CDS             complement(65535..66281)
                     /gene="cas5e"
                     /locus_tag="RHX21_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cas5/CasD"
                     /protein_id="HDV1986059.1"
                     /translation="MSQYLIFQLHGPMASWGVDAPGEVRHTHELPSRSALLGLLAAGV
                     GIRRDDTERLNAFNRHYSLVVCASRNPRWARDYHTIQMPKEVRKARYFSRREELSDPD
                     LLSAIISRRDYYTDAWWMVAVATTADAPYSLEQLQGGLRHPVFPLYLGRKSHPLALPL
                     APLLLEGNASDVLRNAYQQYQDHFHDLKVSLPKLQDECWWEGEHDGLVVSKILRRRDV
                     PLNRQQWLFGERTVNQGPWLSKEEPCTSQE"
     gene            complement(66292..67347)
                     /gene="cas7e"
                     /locus_tag="RHX21_000832"
     CDS             complement(66292..67347)
                     /gene="cas7e"
                     /locus_tag="RHX21_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein
                     Cas7/Cse4/CasC"
                     /protein_id="HDV1986060.1"
                     /translation="MTTFIQLHLLTAYPAANLNRDDTGAPKTVVLGGATRLRVSSQSL
                     KRAWRTSALFEQALAGHIGIRSGRIAREAATILIEKGIEDKKAIEWAAKIADYLGKAK
                     NDKKPKDPLTNAETEQLVHISPAEFDAVKALAHQLAEEKRAPKEEDLSLLRKDRMAVD
                     IAMFGRMLANKPEFNVEAACQVAHAFGVSETIVEDDFFTAVDDLRQASEDAGAGHLGE
                     TGFGSALFYTYICIDKDLLVENLGGDEALANQTIRAFTEAALKVSPTGKQNSFASRAY
                     ASWALAEKGTDQPRSLAAAFYEPINGTRQLDVAVQRITTLRENMNTVYEQKTECASFD
                     VMNKQGSMKDVLDFICA"
     gene            complement(67362..67898)
                     /gene="casB"
                     /locus_tag="RHX21_000833"
     CDS             complement(67362..67898)
                     /gene="casB"
                     /locus_tag="RHX21_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cse2/CasB"
                     /protein_id="HDV1986061.1"
                     /translation="MSIVKDGHKATLRKWHEELQAKRGNRASLRRSTTVNDVCLSEGF
                     RSLLMQTHTLWKIEAQEWRFTALALVAAVAANVKAIDERQPFAAQLAAVMSEGRFTCL
                     SAVKTPDDLLRQLRRAVKLLNGSVNLISLADDIFRWCQESDDLLNHHRRQQRPTEFIR
                     IRWALEYYQAGDADNEQN"
     gene            complement(67895..69457)
                     /gene="casA"
                     /locus_tag="RHX21_000834"
     CDS             complement(67895..69457)
                     /gene="casA"
                     /locus_tag="RHX21_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cse1/CasA"
                     /protein_id="HDV1986062.1"
                     /translation="MNSFSLLTTPWLPVRFKDGTTGKLAPVDLADENVVDIAAPRADL
                     QGAAWQFLLGLLQSSFAPKDYRRWDDIWEDGLEAEKLREALLSLEHAFQFGPDSPSFM
                     QDFEVLMGDKVQVASLLPEIPGAQTTKFNKDHFIKRGVTEHVCSHCSALALFSLQLNA
                     PSGGKGYRTGIRGGGPMTTLIELQEYQGNQQAPLWRKLWLNVMPQDEADLPLPKKFDD
                     LVFPWLGPTRTSELAGAVVTDDQVNKLQAYWGMPRRIRIDFNTTTVGNCDICGEQDDA
                     LLSLMTTKNYGANYAMWQHPLTPYRVPLKEGGEFYSVKPQPGGLIWRDWLGLIETGKS
                     ENNTELPALVVKLFNASSLKQAKVGLWGFGYDFDNMKARCWYEHRFPLLLNKKEGQIP
                     KLRLAAQTASRILSLLRSALKEAWFSDPKGARGDFSFVDIDFWNKTQHRFLRLVRQIE
                     EGQDADGLLSKWNKEIWLFARQDFDERVFTNPYEPVDLKRVMTARKKYFTTSAEKQSA
                     KAAREKKQEAAE"
     gene            complement(69555..72212)
                     /locus_tag="RHX21_000835"
     CDS             complement(69555..72212)
                     /locus_tag="RHX21_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001674509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HDV1986063.1"
                     /translation="MTFFDFWGKTRRGEKDGGDDYHLLCWHSLDVAAMGYLMVKRNCF
                     GLADYFRQLGISDKEQAAQFFAWLLCWHDIGKFARSFQQLYLPPELKIQEGARKNYEK
                     ISHSTLGYWLWNHYLSECQELLPSSSLSPRKLRRVIEMWMPVTTGHHGQPPDRMDELD
                     NFLPEDKAAARDFLLEIKPLFPLIEIPAFWDDDEGIELIKHLSWYISATVVLADWTGS
                     STRFFPRVAHPMDIKGYWQKTLIQAQNALTVFPLKAKVAPFNGINTLFPFIENPTPLQ
                     QKVLDLDISQQGPQLFILEDVTGAGKTEAALILAHRLIAAGKAQGLFFGLPTMATANA
                     MYDRLVKTWLAFYSPESRPSLVLAHSARTLMDRFNESLWSGDLVGSEEPDEQTFSQGC
                     AAWFADSNKKALLAEIGVGTLDQAMMAVMPFKHNNLRLLGLSNKILLADEIHACDAYM
                     SCILEGLIERQARGGNSVILLSATLSQQQRDKLVAAFARGTEGQQEAPFLEKDDYPWL
                     THVTKSDVNSHRVATRKDVERSVSVGWLHSEQESIARIESAVSQGKCIAWIRNSVDDA
                     IKVHRQLLARGVIPTSSLSLFHSRFAFSDRQRIETKTLARFGKEGSSQRAGKALISTQ
                     VLEQSVDCDLDEMISDLAPIDLLIQRAGRLQRHIRDINGQLKRDGKDERSPPELLILA
                     PVWDDSPDEEWFGSAMRNSAYIYPDHGRIWLTQRVLRQQGAIQMPHSARLLIESVYGE
                     DVVMPEGFARSEQEQVGKYYCDRAMAKKFVLNFRPGYAANINDYLPEKLSTRLAEESV
                     SLWLATCIDGVVKPYTTGAHAWEMSVVRVRRSWWKKHRDEFSLLEGEAFRQWCIEQRQ
                     DPEMANVILVTDNESCGYSATEGLIGKVG"
BASE COUNT        16957 a        19806 c        18624 g        16864 t
ORIGIN      
        1 cgctactaaa gccatatcaa gtaagagatg gtgcatccgg gaggattact cgccttgcgg
       61 ctcgcccttc gggccgttgc taaagcaacg ttatcctccc tggtgcttgc ggttagtacc
      121 gccacctctt cgataccttc atcgctgaag attacggaga atatggtgca tccgggagga
      181 ttcgaacctc cgaccgctcg gttcgtagcc gagtactcta tccagctgag ctacggatgc
      241 atcgggaaac ttactttact gcagattttt tgataccgct actaaagccg tatcaagtaa
      301 gagatggtgc atccgggagg attactcgcc ttgcggctcg cccttcgggc cgttgctaaa
      361 gcaacgttat cctccctggt gcctgcggtt ataccgccac ctcttccata ccttcatcgc
      421 tgaaagtacg tagaatatgg tgcatccggg aggattcgaa cctccgaccg ctcggttcgt
      481 agccgagtac tctatccagc tgagctacgg atgcaaatgg cggtgaggcg gggattcgaa
      541 ccccggatgc agcttttgac cgcatactcc cttagcaggg gagcgccttc agcctctcgg
      601 ccacctcacc acacgcctct tacgagtgct tcgaagaact tgtttatcgc tcatcgtcgc
      661 tgcgtggcgc acatattact ttctgagact tataagtcaa acaatttttc ctacactttt
      721 atcgtttgca cacttcacgt tcaattagtc tgtaaaaacg tcaaaaagag tgttttatca
      781 acagaaaaat ggaggtctga cagatagtag taatgcaaaa aaatggagac ttaagttgaa
      841 tgaacgggag taaagcgaaa agactataga gtgaaggaga aattttgagg gtgcgtctca
      901 ccgataaaga tgagacgcgg aaagattagt aactggactg ctgggatttt tcagcctgga
      961 tacgctggta gatctcttca cggtgaacag aaacttcctt cggggcattt acgccaatac
     1021 gtacctggtt gccctttacc cctaaaactg tcacggtgac ctcatcccca atcatgaggg
     1081 tctcaccaac tcgacgagtc agaatcagca ttctttgctc cttgaaagat taaaagagtc
     1141 gggtctctct gtatcccggc attatccatc atataacgcc aaaaagtaag caatgacaaa
     1201 cacattacat gtaagcagtc atggcattac attctgttaa acctaagttt agccgatata
     1261 cacaacttca acctgacttt atcgttgtcg atagcgttaa tgcgaatgcc gtgaagcgag
     1321 tccacggcat tgcctgacgc ttatattatt gcaatttcgc gctgacccag cctttcacac
     1381 tggctaacgc tgcaggtaag gccgcagcat ccgtaccacc ggcttgcgcc atgtcaggac
     1441 gtccaccacc cttgccgccc acctgctgag cgaccatacc aatcagttcc cctgctttca
     1501 cacgatctgt gacgtcctta gatacgcctg caatcagaga aaccttacct tcggctaccg
     1561 ttgccagcac gataattgtc gaccccagct gattttttaa atcgtcaacc atggtacgca
     1621 acattttcgg ctcaacaccg ctaagctcgc taaccaacag cttaacacca ttaacatcaa
     1681 ttgccttact ggaaagattt gcgctctcct gtgcggcagc ttgttcttta agctgttgta
     1741 gttctttttc taactgacgc gtacgttcca gtactgagcg cactttatcc gccagattat
     1801 tgctatcgcc tttcagcaga tgcgcgactt cgcttaagcg atcgctgtct gcatgaacgg
     1861 tggtgatagc gccttctccg gttaccgctt cgatacgacg aacgcctgca gcagtacccg
     1921 attcagagat gatgcggaac agaccaatat caccagtgcg gctggcgtga gtaccgccac
     1981 acagctcggt ggagaaatcg cccatgctca gcacgcgtac acgctcatca tacttctcgc
     2041 cgaacagcgc catcgcacct ttcgctttcg ccgcttcgag atccatgatg ttggtttcga
     2101 tcggcaaatt gcgacgaatc tgtgcgttca ccaggtcttc gaccgcacga atctcttccg
     2161 gtttcatcgc ttcgttgtgt gagaagtcga agcgcagcac cttgtcgtta accagtgaac
     2221 ctttctgcga tacatgagtc cccagaacct ggcgcagcgc agcgtgcatc aggtgcgttg
     2281 cggagtgatt cagacgaata cgggcgcgac gagcctcatc aacatcagcc tgcacagcgt
     2341 cgcccacttt cagagaaccc gcagcaagtt taccgatgtg accaatcgcc tggccgtatt
     2401 tctgcgtatc ttccaccgcg aaggagaagt tagcgccttt cagttcgcct ttatcaccaa
     2461 cctgaccgcc ggattccgca tagaatggtg tttgatccag cacgaccaca gcttcctggc
     2521 ctgcattgat ggcatcaacc gctttaccat caacaaacag cgcggtcact ttgccgttca
     2581 gttccagatg gtcatagcct ttaaattcag atgcactatc aacacggatc attgcgttgt
     2641 aatcggcacc aaagccgctg gcttcgcgcg cgcgacgacg ctgctcttcc attgctgctt
     2701 caaaaccagc ttcgtcaact ttgatgttgc gctcacgaca aacatcagcc gtcaggtcaa
     2761 ccgggaagcc ataggtgtcg tacagacgga aagccgtttc accatccagc gtatcaccag
     2821 aaagttttgc cagctcttca tccagcaacg ccagaccgcg ctccagagta cgggcaaact
     2881 gctcttcttc agtcttcagc acctgctcaa cctgcgcctg ctggcgtttc aggtcttcac
     2941 ccgcagagcc cataacgtcg atcagcggac caaccagttt gtagaagaag gtttctttcg
     3001 cgccgagcat attgccgtga cgcactgcgc gacgaatgat acgacgcagt acataaccac
     3061 ggttttcatt ggacggcatt acgccatccg cgatcaggaa cgcacaagaa cgaatgtggt
     3121 cagcgattac gcgcagcgat ttattgctca gatcggtcgc gccagtgact ttcgctaccg
     3181 cctggatcaa cgtgcggaac aggtcgatgt catagttaga gttaacgtgt tgcagcaccg
     3241 cagcaatacg ctccagaccc ataccggtat ctacagacgg cttcggcagc ggttccatcg
     3301 tgccatctgc ctggcggttg aactgcatga agacgatgtt ccagatctca atgtagcggt
     3361 cgccgtcttc ttccggactt cccggagggc caccccaaat gtggtcgccg tgatcgtaga
     3421 agatttcggt gcacgggccg cacggaccag tgtcacccat ctgccagaag ttgtcagatg
     3481 cgtatggcgc acctttgtta tcgccgatgc gaataatacg ttcgcgcggg atccctactt
     3541 ctttttccca gatttcgtag gcttcgtcgt cgctttcata gacggtaacc cacagacgct
     3601 ctttcggcag ggcaaaccat ttttcgctgg tcagcagttc ccatgcaaac tgaatggcat
     3661 cgtgtttgaa atagtcgccg aagctgaagt tgcccagcat ttcgaagaag gtatggtgac
     3721 gcgcggtgta accgacgttt tccaggtcgt tgtgtttacc acccgcacgc acgcagcgtt
     3781 gggaagtggt agcgcgggaa taattacgct tgtcgagccc aaggaacaca tccttgaact
     3841 ggttcatccc ggcgttggta aacaacaaag ttgggtcgtt atggggtacc agggagctgc
     3901 tggcaactac ctgatgtccc ttactatgga aaaagtcgag aaacgcctga cggatctcag
     3961 cggtgctctt gctcataatt atcctgaaat caagctaacg aaatatcgcc accagctcca
     4021 gcgtgtctta accgccgggc tggtaactga aaagtgggaa taagataagt tttcttgact
     4081 gggaagtaaa ataccgtatg cgttcagtcg gcaaaatttc gccaaatatc ctggatatct
     4141 tccatcagat agccacgata gagcaaaaaa cgctggatct taactttttc tgaaaagaca
     4201 gttggcaaag gttcaccata ttttcgcgtc gcctgatcgc gcgccagtgc gcaccagtcg
     4261 atgtcacatt cacgcatcgc tttttctgtc gcttcgcggg aaataccttt ctgattcagt
     4321 tcctggcgaa tacgcgcagg tccataacct ttgcggctac ggctggcgat aaagcgcgca
     4381 acaaatcggc tgtcatcgag atagccatgt tcatggcacc aggcaataac gcgctcgtaa
     4441 tcttctgccg tagcatcaat ctcttctggg ccatttttgc ccataatcgg tgccgcgagt
     4501 ttacgtcgca gttcttgctc actgtgatcg cgcaccgcca gaatgcgtac cgcacgatcc
     4561 aacaggcgag catatgccgg gcgacgggac gttgattctg tcatggcata tccttacaac
     4621 ttaaaaaagc aaaagggccg cagatgcgac ccaggttttg ctgataaaca gatttaatag
     4681 tcaatgagtg tgcagaatgt tcccgcaggc ccaattcgtt agaggatcga ggtgagagta
     4741 atttttcacg ccagtgctgg cctgttcccc tcaccctaac cctctcccca aaggagcgag
     4801 gggaccgtcc gtgcacacat tatctattat catcaataac gaacgattaa aaatcttcgt
     4861 tagtttctgc tacgccttcg ctgtcatcta cagagaaatc cggcgttgag ttcgggttgc
     4921 tcagcagcaa ctcacgtact ttcttctcga tctctttcgc ggtttccggg ttatctttca
     4981 gccaggcagt tgcattcgct ttaccctgac cgatcttctc acctttgtag ctgtaccacg
     5041 cgcctgcttt ctcgatcagc ttctctttta cgcccaggtc aaccagttcg ccgtagaagt
     5101 tgataccttc gccgtagagg atctgaaatt cagcctgttt aaacggtgca gcgattttgt
     5161 tcttcaccac tttcacgcgg gtttcgctac ccaccacgtt ttcgccctct ttcaccgcgc
     5221 cgatacgacg gatgtcgaga cgaacagagg cgtagaattt cagcgcgtta ccaccggtag
     5281 tggtttccgg gttaccgaac atcacaccaa ttttcatacg gatctggttg atgaagatca
     5341 gcagcgtgtt ggactgcttc aggttacccg ccagcttacg catcgcctgg ctcatcatac
     5401 gtgccgcaag gcccatgtga gagtcgccga tttcgccttc gatttccgct ttcggcgtca
     5461 gtgccgccac ggagtcaacg acgataacgt ctactgcgcc agaacgcgcc agggcgtcac
     5521 agatttccag tgcctgctcg ccggtgtccg gctgggagca cagcaggtta tcaatatcga
     5581 cgcccagttt acgtgcgtag attgggtcca gcgcgtgttc agcatcgata aacgcacagg
     5641 ttttaccttc acgctgcgct gcggcgatca cctgcagcgt cagcgtggtt ttaccggaag
     5701 attccggtcc gtagatttcg acgatacggc ccatcggcag accacctgcc ccaagcgcga
     5761 tatccagtga aagcgaaccg gtagagatgg tttccacatc catggaacgg tcttcaccca
     5821 ggcgcatgat ggagccttta ccaaattgtt tctcaatctg gcccagtgct gccgccaacg
     5881 ctttctgttt gttttcgtcg atagccattt ttactcctgt catgccgggt aataccggat
     5941 agtcaatatg ttctgttgaa gcaattatac tgtatgctca tacagtatca agtgttttgt
     6001 agaaattgtt gccacaaggt ctgcaatgca tacgcagtag cctgacgacg caccgcatca
     6061 cggtcaccgc tgaagcattc ccgccgggta atgccttcac cgcgggcagt ggcaaaagca
     6121 aaccagacgg tgccgacagg cttctcttca ctgccgccat ccggcccggc gataccacta
     6181 atagacacgg cataatcagc acgagccgct ttcagtgcac ctatcgccat ttccaccacg
     6241 acgggttcac tcaccgcgcc atgctgcgcc agcgtctctt cgcgtacgcc gatcatctgc
     6301 gctttggctt cgttactgta ggtgacaaat ccgcgttcaa accaggcgga gctaccggca
     6361 atatcggtaa tcactttcgc tacccaacca ccggtacaag actcggcagt tgttacggtt
     6421 gcgccacggg ctttcagcgc ctgcccaacc tgttcactta actgcatcag ttcactgtca
     6481 gtcatcacaa cctctgtcag tcaaaaattt atgccggaca agatagcact ttcgtcagga
     6541 agatggtgtt ggcgttgcaa ttttacgagg aggattcaga aaaaagctga ttagccagag
     6601 ggaagctcac gcccccctct tgcaaatagt tactgcacgc gcgccagcgc cacggcttgt
     6661 cctaactgcc agaccgccat tgcgtaatgg gtgctgtggt tataacgggt aatggtgtag
     6721 aagttcggca gaccgtacca gtactggtaa ccggtaccga catccagacg cagcaggctg
     6781 gcttgttgat ggttgcccag cggctgctgt ggcgttaaac ctgccgtggc aagctgcgaa
     6841 atgctgtacc tggttttgaa gccatttggc aagcctggag cctgaccgtt tgccattacc
     6901 gcgacctgat cgcctttcac ccagccgtgc gctttgaaat agttcgccac gctaccgatc
     6961 gcatcaaccg gatcccacag gttgatatgc ccgtcgccgc tgaaatctac cgcatattgt
     7021 ttgtaagacg acggcataaa ctgtccgtag cccatcgccc cggcaaagga acctttcaga
     7081 ttgagcggat cgtcctgctc gtcgcgcgcc atcaacagga aggtttccag ctcgccagag
     7141 aaatactccg cgcggcgtgg gtagttaaat gacagcgttg ccagcgcatc gaggatgcga
     7201 gttttcccca tcacgcgccc ccagcgggtt tcaacgccga taatcccgac gataatttcc
     7261 ggcggtacgc catacacctg ccacgcgcga ttcaacgcat cttcatactg attccagaaa
     7321 accacaccgt tctgcacgtt gtccggcgta ataaattttt tgcgataacg gagccatgcg
     7381 ccgttcggac ctgatggcgg tttcaccgat gtggttggtg cctggttatc catcagccgc
     7441 agtaccgaat ccagacgctt cgcctgggag agaatttcct gcaactgctg acgatcgaaa
     7501 ccgtgtttgt tcaccatttt gtcgatgaac tgctgggcat tcgggttatt agcgaaatcg
     7561 ccgcccatct gcatcacatt gtgctgcggc tcaagcagga agccgccaga cggcgttccg
     7621 gtggtcgttt cagtctcagt aggttttggc ttgctgctac aggcggcaag caacacaaaa
     7681 aggggaagca atgttacata acgacgcttg aacatgaggg gtccatttaa cagattcaac
     7741 caggggcaag tatggtaaag catcacgccc cacacaagga agcggtagtc actgcccgat
     7801 acggacttta cataactcaa ctcattcccc tcgctatcct tttactcaaa ctttcaaatt
     7861 aaaatattta tctttcattt tgagatcaaa ataacacttt taaatctttc aatctgatta
     7921 tattaggttg ccgtttggta ataaaacaat aaatcctgaa ggagagaaca atgatagaaa
     7981 ccattactca tggtgcagag tggtttatcg ggctgttcca aaagggcgga gaggtgttta
     8041 ccgggatggt gaccggcatt cttccgctgt tgattagcct gctggttatc atgaacgcac
     8101 tgattaattt tatcggtcag catcgtattg aacgttttgc tcaacgttgc gccggtaacc
     8161 ctgtttcccg ttacctactg ttaccgtgca ttggcacgtt tgtcttttgc aatccgatga
     8221 ccttaagcct gggtcgcttt atgccggaaa agtacaaacc cagctactac gcggcggcct
     8281 cttatagctg ccactcaatg aatggcctct tcccccatat caaccctggc gaactgtttg
     8341 tttatcttgg cattgccagc ggtctgacaa cgctgaacct gccacttggc ccactggcgg
     8401 tgagttatct gctggttggt ctggtcacca atttcttccg cggctgggtg accgatctga
     8461 ccaccgccat ttttgagaaa aagatgggca ttcaacttga acaaaaagtt cacctggcag
     8521 gagcaacatc atgacgcata ttcggatcga aaaaggaacg ggtggctggg gcggcccgct
     8581 tgagctgaaa gccacgccgg gaaaaaaaat cgtctatatc accgccggta cccggcctgc
     8641 gattgttgac aaactggcac agcttactgg ctggcaggct attgacggat ttaaagaagg
     8701 tgaacccgcg gaggcggaaa ttggtgtcgc ggtaatcgac tgtggcggca cattacgctg
     8761 cggcatctat ccgaaacgac gtattcccac cattaatatc cactcgacgg gcaagtccgg
     8821 tccgctggcg cagtacattg tggaagatat ttatgtctct ggcgtaaaag aagaaaacat
     8881 cactgtagtg ggtgatgcga caccacaacc ctcttccgtg ggccgtgact atgacaccag
     8941 taagaaaatc accgaacaaa gcgatggttt actggcgaag gtgggaatgg gcatggggtc
     9001 cgccgttgcg gtgctgtttc aatctggtcg tgacaccatc gacactgtat taaaaaccat
     9061 tctgccgttt atggcattcg tctcggcgct cattggcatc attatggctt ctggccttgg
     9121 tgactggatt gcccacggtc ttgctccgct ggcgagccat ccactgggtc tggtcatgct
     9181 ggcgctcatc tgctccttcc cactgctttc acctttcctc ggcccaggcg cagttatcgc
     9241 acaggttatc ggcgtattga ttggcgtgca gattggtctc ggcaatattc cgccgcatct
     9301 ggctttaccg gcactgtttg ccatcaacgc gcaggcggcc tgcgacttca tcccggtcgg
     9361 tttgtcgctg gcggaagccc gtcaggacac ggttcgcgtc ggtgtccctt ctgtactggt
     9421 gagccgcttt ttaaccggcg cgccgactgt actgatcgcc tggtttgtct ccggttttat
     9481 ctatcaatag aggctgaaac atgaccgtta tttatcagac caccatcacc cgtatcggcg
     9541 cgagtgccac tgacgccctc agcgaccaga tgctcatcac ctttcgtgaa ggcgcgccag
     9601 cggacctcga agagtattgc ttcattcatt gccacggcga gttgaaaggt gcactccatc
     9661 ccggtttgca attttcactc gggcagcatc gctatccggt gaccgctgtt ggcagcgtgg
     9721 cggaagacaa ccttcgcgaa ctgggtcatg tcaccctgcg cttcgatggt ttaaacgaag
     9781 cggaatttcc gggcactgtc catgtggcag gccctgtccc cgacgatatc gcgccgggat
     9841 cggttttgaa gtttgaatct gttaaggagt aaaaaatgaa tcaggttgcc gttgtcatcg
     9901 gtggtgggca aaccttaggc gcgttcctgt gccacggtct ggctgccgag gggtatcgcg
     9961 tcgcggttgt cgatattcag agcgacaaag ccgcaaatgt ggcacaagaa attaacgccg
    10021 aatatggtga aagtatggcg tacggttttg gtgctgacgc cactagcgag caaagcgttc
    10081 tggcgctctc tcgtggggta gatgaaatct ttggtcgcgt ggatttgctg gtctacagcg
    10141 ccggaatagc aaaagcagcc tttatcagcg acttccagct cggcgatttt gaccgttcgc
    10201 tacaggtgaa tctggtgggt tatttcctgt gtgcgcgtga attttcgcgt ttgatgatcc
    10261 gcgacgggat tcaggggcgc attattcaga tcaactcgaa atccggcaaa gtgggcagca
    10321 aacacaactc tggctacagc gcagcgaaat ttggtggcgt cgggctgact caatcactgg
    10381 cgctggatct ggcggagtac ggcattacgg tgcattcact gatgctcggt aacctgctga
    10441 aatcgccgat gttccagtca ctgttgccac aatacgcgac caagctgggt atcaaaccgg
    10501 atcaagtcga gcagtattac atcgacaaag taccgctcaa acgcggctgc gattatcaag
    10561 atgtgctgaa tatgctgctg ttctacgcca gtcctaaggc gtcgtactgc accggacagt
    10621 cgatcaatgt caccggcggt caggtgatgt tctgatcaac agcggagatc cattaaggat
    10681 ctccgtgaga ctatagaatg cctgatgcgc tacgctcatc aggcatacag gacttccgcc
    10741 actacattaa ggaaaagtta tggtatccgc actcatcacc gtcgccgtta tcgcctggtg
    10801 tgcgcaactg gccttaggcg gctggcaaat ttctcgtttt aaccgtgcct tcgacacact
    10861 atgccagcaa gggcgggttg gcgtgggccg ttccagcggg cgctttaaac cgcgggtcgt
    10921 ggtcgccatc gcgctggacg atcagcagcg catcgtcgac accttgttta tgaaaggact
    10981 gaccgtcttc gcccgaccgc aaaaaattcc cgcaattacc ggtatgcatg cgggtgattt
    11041 acagcccgat gtgatctttc cccatgatcc actatcacag aatgctctat cattggcgct
    11101 taaactgaaa cgtggataat ttcgttgtga atgttacttg cttgcgaagt tatcattttg
    11161 aaacctaaat caggtaatca cgcccatgaa acctcgtcag cgtcaggccg ccattctgga
    11221 gtatctgcaa aagcagggta aatgctcggt tgaagaattg gcgcaatact ttgacaccac
    11281 aggcacaacc attcgcaaag atctggtcat tctggaacat gccggaaccg tcattcgtac
    11341 ttatggcgga gtggtgttga ataaagagga atccgatccg cctatcgatc ataaaacact
    11401 catcaacacc cacaagaaag agctgattgc agaagctgcc gttagtttta tccatgatgg
    11461 cgattcgatc attcttgatg ctggcagtac cgttttgcag atggttcccc tgctctcgcg
    11521 ctttaataac atcacggtga tgaccaacag cctgcatatc gtcaatgcgc tatccgaact
    11581 ggataacgaa caaactatcc tgatgccagg cggaacgttt cgtaaaaaat cggcctcatt
    11641 tcacggacag ctggcagaga atgccttcga acatttcagt ttcgataaat tgtttatggg
    11701 caccgacggc atcgatctca atgcgggcgt aaccaccttc aacgaggttt ataccgtcag
    11761 taaggcaatg tgcaatgccg cgcgcgaagt gattttgatg gcggactcat caaagtttgg
    11821 ccgtaaaagc cccaacgtag tttgcagtct tgaaagcgtc gataagctga ttaccgacgc
    11881 aggtatcgat ccggcgtttc gtcaggcgct ggaagagaaa gggatcgatg tgatcataac
    11941 cggagagagc aatgagtgaa gcactactga acgcgggacg tcagacgtta atgctggagt
    12001 tgcaggaagc aagccgttta ccggaacgtc tgggcgatga ttttgttcgc gccgccaata
    12061 tcatcctgca ctgcgaaggc aaagtggtgg tttcgggaat tggcaaatcg ggccacattg
    12121 gtaagaaaat cgccgcaaca cttgccagta ccggcacacc ggcttttttt gtccatccgg
    12181 cagaagcact gcacggcgat ctggggatga ttgaaagccg cgatgtgatg ctgtttatct
    12241 cttactccgg tggcgcgaag gaactggatc tgattattcc gcgtctggaa gataaatcta
    12301 tcgcgctgct ggcgatgacc ggcaaaccga cgtcaccgct gggcctggcg gcaaaagcgg
    12361 tgctggatat ctccgtagaa cgcgaagcct gcccgatgca ccttgcgccg acctccagca
    12421 ccgtcaatac cctgatgatg ggtgacgcgc tggcgatggc ggtcatgcag gcgcgcggat
    12481 ttaatgaaga agattttgcc cgctcccacc cagccggggc actgggcgct cgcttgctga
    12541 ataaagtgca tcatctgatg cgccgtgacg atgccatccc acaggtggcg ttaaccgcca
    12601 gcgtgatgga tgcgatgctg gaactcagcc gcaccggtct ggggctggtg gcggtatgtg
    12661 acgctcaaca acaggtacaa ggcgtcttta ccgacggcga tttacgtcgc tggctggttg
    12721 gcggcggcgc actcaccacg ccagttaatg aagcgatgac gacaggcggc accacattac
    12781 aggcacaaag tcgcgccatc gacgccaaag agatcctgat gaagcgcaaa atcactgccg
    12841 caccggtggt ggatgaaaac ggcaaactca ccggcgcaat taacctgcag gatttctatc
    12901 aggccgggat tatttaatcc ttcaatccca gacgtttcgc cagccgatgc aggttggcga
    12961 cgtcggtttc cagcatccgc gcgcaggcag cccagttgtg atgattttgt gccagtgcct
    13021 ggcgaatggt ttcacgctgg aacgcttctg tcgcttcacg caggttttgc ttaacaacgg
    13081 gcaccgccgc cgcttctggc ggcggcaacg tcacctcagg aaaagcaaaa tgttgtgcct
    13141 caagaatcac ttcatcgccg ctgcgagtgg ctctcgccag cactaccgcc cgatgaatag
    13201 catgttccag ttcgcgcacg ttccccggaa aacgatagtg ttgcagtaaa tttcgcgctc
    13261 cggcacttaa taccacgcgg gagagcccca gccgcaaacg acactgctcg cagaaatacc
    13321 ccgccagcag aatgacatca tcgccccgct cacgcagcgg cggcaccgaa agtggaaaca
    13381 cgctcaggcg atgaaacaaa tcggcgcgga atcgccctgc cagcacctct tcgcgtaagt
    13441 cgcggttagt cgccgccagc acgcgcacat cgacccgcaa actacagtca tcgccaacgc
    13501 gctgaatatc gccatactgc aacaccctca gcagcttggc ctgcaatgcc aacgacaact
    13561 cgccgatctc atcgagaaac agagtgccgt tatccgccat ttcaaacttc ccgctgcggt
    13621 tactgatagc gccagtaaac gctcctttca catgcccgaa caactcactt tccgccacac
    13681 tttccggcag tgcggcacag ttgagataga ccagcggatt caccgcccgt ggcgaggctt
    13741 catgaatcgc tttcgccacc agctccttac cggttcccgt ctcaccgctg atcaggacgt
    13801 tgagatcgga cgccgccaca atctcaatct cttttttcag ttgcgtcatg ccaggggaca
    13861 agccaatcat ctgcgtctgt ttcaccgctt caaacggcgt ggcatcgcct ggcatcatat
    13921 tctggctttc cagttgttca atcagcaacg cattgcttaa cgctcccgcc gccagcgcag
    13981 caatcagccg tagctcttcg tcgctgaaaa catcgaactg atcgggctgc atcccgtcga
    14041 gcgtcagtgc gccgatcagg ttttgcccgg caaacaatgg cagaccaacg caggcgtgaa
    14101 ccttcagact ctcctgccca ggaatcaaac cgtcataggg atcgggcaat tcgctgtctg
    14161 caggaaagcg caccacgtcc ccggcgcggg caatcgcttc aagccgtgga tgcccttcca
    14221 gcgcaaagcg tctaccgagt acatcctttg ccagaccgtc gatggcaagc ggaataaact
    14281 gccgcgaatc gtaacgtagc aacgcagacg catcgcactc cagcacctga cgtagcgtgg
    14341 tgatcaggcg ctgaaaacga tcctgatgac caatcccacg ctgcaattcg atggcgatat
    14401 tcgccagcac atcaacggaa aaactcatct ttgcctcact gtcaatttga ctatagatat
    14461 tgtcatatcg accatttgat tgatagtcat tttgactacc cattaatgag catactttta
    14521 tttatatagt aaaaacaatc agataaaaaa ctggcacgca atctgcaatt agcaagacat
    14581 ctttttagaa cacgctgaat aaattgaggt tgctatgtct attgtggtga aaaataacat
    14641 tcattgggtt ggtcaacgtg actgggaagt gcgtgatttt cacggcacgg aatataaaac
    14701 gctgcgcggc agcagttaca acagctacct catccgcgaa gaaaaaaacg tgctgatcga
    14761 caccgtcgac cataaattca gccgcgaatt tgtgcagaac ctgcgtaatg aaatcgatct
    14821 ggcggatatc gattacatcg tgattaacca tgcagaagag gaccacgctg gggcgctgac
    14881 cgaactgatg gcgcaaattc ccgatacgcc gatctactgt actgccaacg ctatcgactc
    14941 gataaatggt catcaccatc atccggagtg gaattttaat gtggtgaaaa ctggcgacac
    15001 gctggatatc ggcaacggca aacagctcat ttttgtcgaa acaccaatgc tgcactggcc
    15061 ggacagcatg atgacttacc tgacaggcga cgcggtgctg ttcagtaacg atgctttcgg
    15121 tcagcactac tgcgacgagc atctgttcaa cgatgaagtg gatcagacgg agcttttcga
    15181 gcagtgccag cgttactacg ccaatatcct gacgccgttc agccgcctgg taacgccgaa
    15241 aattaccgag atcctgggct ttaacttacc agtcgatatg atagccactt cccacggcgt
    15301 ggtatggcgc gataacccga cgcaaattgt cgagctgtac ctgaaatggg cggctgatta
    15361 tcaggaagac agaatcacca ttttctacga caccatgtcg aataacaccc gcatgatggc
    15421 tgacgctatc gcccagggga ttgcggaaac cgacccacgc gtggcggtga aaattttcaa
    15481 cgtcgcccga agcgataaaa acgaaatcct gactaatgtc ttccgctcaa aaggcgtgct
    15541 ggtcggcact tcgacgatga ataacgtgat gatgccgaaa atcgccgggc tggtggaaga
    15601 gatgactggt ttacgcttcc gtaacaaacg cgccagtgct ttcggctctc acggctggag
    15661 cggcggtgcg gtggatcgtc tttccacgcg cctgcaggat gcgggtttcg aaatgtcgct
    15721 tagcctgaaa gccaaatggc gaccagacca ggacgctctg gagttatgtc gtgaacacgg
    15781 tcgcgaaatc gcccgtcagt gggcgctcgc gccgctgccg cagagcacgg tgaatacggt
    15841 ggttaaagaa gaaacctctg ccaccacgac ggctgacctc ggcccacgga tgcagtgcag
    15901 cgtctgccag tggatttacg atccggcaaa aggcgagcca atgcaggacg ttgcgccagg
    15961 aacgccgtgg agtgaagtcc cggataactt cctctgcccg gaatgctccc tcggcaaaga
    16021 cgtctttgac gaactggcat cggaggcaaa atgagtaacg gcattgtgat catcggttcg
    16081 ggcttcgccg cccgccaact ggtgaaaaat attcgcaaac aggacgccac tattccatta
    16141 accctgattg ccgccgacag catggatgag tacaacaaac ctgacctcag ccatgttatc
    16201 agtcaggggc aacgtgccga tgaccttacc cgccagacgg cgggtgaatt tgccgagcag
    16261 tttaatctgc acctgtttcc acaaacctgg gtgacggata tcgatgccga agcccgtgtg
    16321 gtgaaaagcc agaataatca gtggcaatac gacaagctag tactggcaac cggtgccagt
    16381 gcctttgtcc cgcctgtgcc tgggcgtgag ttaatgctga cgttaaatag tcagcaagag
    16441 tatcgcgcct gtgaaacgca actgcgggat gcccgacgcg tgttgattgt tggcggtggt
    16501 ttgattggta gcgaactggc gatggatttt tgtcgtgcag gcaaagcggt cacgctaatc
    16561 gacaacgctg ccagtattct ggcgtcatta atgccaccgg aagtaagcag ccgcttgcag
    16621 catcggttga cggagatggg cgttcatctg ttgttgaaat ctcagttgca ggggctggaa
    16681 aaaacagatt ctggcattct ggcaacgctg gaccgccagc gcagtatcga agtggatgcg
    16741 gtaattgccg ccaccggact gcgcccggaa accgccctgg cacgacgcgc cgggctgacg
    16801 attaatcgcg gcgtttgcgt cgatagttat ctgcaaacca gtaatgccga tatttacgcg
    16861 ctgggcgatt gcgcggaaat taacggtcag gtattgccgt tcctccagcc gattcaactt
    16921 agcgcgatgg tgctggcaaa aaatcttctc ggcaataaca cgccactgaa actaccggcg
    16981 atgctggtga aaatcaaaac gccggaatta ccgctgcatc tggcaggcga aacccagcgt
    17041 caggatttac gctggcaaat taataccgaa cgccagggaa tggtggcgcg cggcgttgac
    17101 gatgctgacc agcttcgcgc ctttgtggtc agtgaggatc ggatgaaaga ggcatttgga
    17161 ttgttgaaaa cattgccgat gtaggtgggc tactgtgcct aaaatgtcgg atgcgacgct
    17221 ggcgcgtctt atccaaccta cggggagcgc atgtgttggt cacatactgc gttcatgtcg
    17281 catccaccta ctgtgcccaa aatgtcggat gcgacgctgg cgcgtcttat ccgacctacg
    17341 gggacgcatg tgtaggccgg ataaggcgtt tacgccgcat ccggcaatgg tgtccaaatg
    17401 caacacgttt tatccgttct ggacttcacc cgctaaccaa cgcgccgcag caataacccc
    17461 ctgccccaga gacaaaccgc catcacccgc cggtaaactc tgtggaaaga gcaatgtgaa
    17521 atcagcgaga taatgcgcca gacgtgcacg cagcaaacgg ttatgaataa ccccgccgct
    17581 aaataccagc gtagtgatac cacgcatcgt ggcctgctca cgcatcaacg cggcaaaacc
    17641 ctgcgccagc gcatcatgaa acgcccacgc gcgttgatta accggtgcct gccagttcag
    17701 ccactgctgc cagaaagtgg cgagatccag ttgattgtcc accagcggca ttgtcaccgg
    17761 atgcgtcact ccgtggcacg aagctgcgag tgcctccaga gcacaagccg cttcaccttc
    17821 ataacttaac gtggctggcg cacagcccag tgccgccgcc acggcatcga acaaccgccc
    17881 acacgatgac gccagcggcg cgttaattcc acgctcaatg gcccgcgcca gcacgctcca
    17941 gttttgctgt tgcacacttg ctgtttcaga ataattctgc cactccggca caaagcgcag
    18001 gcactgcgcc agcaggtttc gccacggctg cttcgccgcc aaatcgccac ccggaagcgc
    18061 cactgcaggc aagccgccca ggtgctcaca ttcgcgatag ttcacccgca gacactcgcc
    18121 gccccacaaa gcgccgttct cccccatacc gataccatcg agcgtcaaag caatgacatc
    18181 accgccatcc agcggccact gatgctctgc cagacacgcc gctgcgtggg catgatgatg
    18241 cagcaccgtt tgcgtcggca gattcatttc gcgcgcccac tggctggaga catagcccgg
    18301 atgtgcgtca tgcacaacgt attgcggggt gaaatcgtag atgttttgca tcaggcgtaa
    18361 cgcttcgcgc cactgcatct ggatgccatc gtcacttaaa tcgcccagat gctgactcaa
    18421 cactgcttgt tcaccgcgca ccaggcagaa ggtgtttttc agatctgcgc cgagacacag
    18481 cacaggcggc acatttttaa agcccggagg caaagccagt gcgtccggta catacccccg
    18541 cgaacggcgc agcatttcgc cgctttcgcg caccaccgaa tcatccatcc gctgcacgat
    18601 gtcgcggtta tgtatcaaga atccgtcggc aatgccctgc aaatccgcca gcgcctgttc
    18661 gttgctgata gccggtggtt taccgctcag gttgccggag gtcatcacca gcgggcattg
    18721 cagttcctgt aacagcaaat gctggagcgg gttcgcaggc aacatcacgc cgacttcgtt
    18781 aaggccaggg gcgatatcat cacaaagctc aggaacgtat tttttatcca ccagcacaat
    18841 cggcgcggcg ggcgtggtaa gcaactggcg cgcagcgtct ggtaaacctt ctgccactgg
    18901 caagatgacc gccagcggtt tcgccgggcg atgtttgcgc gcccgaagtg tcgccaccgc
    18961 ggtactgtta cgtgcatcgc aggcaagatg aaatccgcca atccctttga tggcgacaat
    19021 gttgcccatt tttaactgtg cgatagccgc ctgtaatgcc gcctcttgtt ccgcatgttc
    19081 accatgactt acccattcaa gatgtgggcc acactccggg caggccaccg gctgggcgtg
    19141 gaagcgacga tcgagcgggt cgcggtactc tttatcacag gctggacaca gcggaaactc
    19201 cgccattacg gtaaacgggc ggtcgtaagg catggcgcga ataatggtga aacgcgggcc
    19261 gcagtgggta cagttgataa acggataacg ataacgccgt tcgcctgggg tattcatttc
    19321 ggcaaggcaa gcagggcaag tagcggcatc cgggacaatt tgcgtattca tggcacctcc
    19381 cgcgctctgg cggatagtga actcggtggg cagttgtgac cagataaacg gctcacgctc
    19441 gacgctatca atacgcgcca gtggcggaca gtgctgatgc aattgaacaa gaaacgtttc
    19501 cgggtcttcc agcagccgga cttctacgcc atcgccgtca ttacagacat cgccgtgaag
    19561 atttaattgc tgtgccagct gccagacaaa cggacgaaaa ccgacgccct gcactttgcc
    19621 acgaatacgc agttggacac cgcaagatgt gttttttgcc attgagttat tcccgccatc
    19681 atgaattgcg taacccgtcc agccggacac gacagcgtcg catccggcag tcacaggtcg
    19741 gcgataccgc ccgcttcgta ttctacgaat atttccggga attcctttga tgccagaaca
    19801 gttctgtaag atttttagaa catcagcgcc gtacggcggc gtttttctgc gctcagttgt
    19861 tcaagtttat tacgatcgac acaaattagc gcatgggtcg ggcaagccgc catacacgcc
    19921 gggccgtctt cacgatggtt gcacaggtcg catttattgg cttcagcttt gtcagcccgt
    19981 acattcagcc ccgcgccgct gttgcggatc accggacgta ccaccacttc catcgcgcca
    20041 tacgggcaag ccaccacgca ggttttgcaa ccaatgcaac gttcctgcat cacatgaaca
    20101 aaccctttat cacggctgat agcaccattc gggcagacgt tagcgcacgg tgcatcttca
    20161 cactgacggc agactgtcgc cgtggaaatg ttcacacctt taatgacatg gattcgcggt
    20221 aaaaaggttt ccggggtcag cgatgcacag tcctgatttt cctgatgaga aaccacgcac
    20281 gccacttcac aggtacggca accaatacat ttactcgcgt cagcaatgat gaaacggttc
    20341 atcaaattct ccagcaatga cagttaatgc gccgatacat tcacaaatca tgccagtttt
    20401 taatttgctg ttatttaagg aaattaattt ctgtaatgca ggaaaaaaga tgtcatcgac
    20461 actagtgacg atgacatgtg atgacaatgt ttatcgcgaa agggcaatga gtgagtcgcg
    20521 gcggatcagt tttccgctga aggttttcgg cggtgagaaa tccccgccat cgagcataaa
    20581 aatcagccgt ccaataattt cctgaatcat ctctgttacc ggaattttta cgctggagag
    20641 cgccggaacg gtgtaggggg caattgcgat atcatcgaat ccgataactg acacctgctc
    20701 tggcaccgct acgccgcgct cgtgcaacgc tttcatcgca cctatcgcca tatcgtcgtt
    20761 actggcaact aacgcgctaa atttagcccc acgttcgagc aacgtttcta ccccttcggc
    20821 cccgctggcg ggcgtccatt taccgttagc gataagtttt tcattgagcg caataccatg
    20881 ctgcgccagc gcgtctttat acccagcaag acgttcaatg ctggtggggg aatccatcga
    20941 gccggtaagg aaagcaatct cctgatgtcc ggcgtttatc aactctgcca cggcattaaa
    21001 gctggtctgt ttatgatcgc accagacgct atggctgctg tttttgcgca ggcggcgatt
    21061 aagcaccatt atcggctgac tgtgcgcgtc aatgatgtca tcaatctcat ccacgcttaa
    21121 aaaacgcggg taaatcataa tggcgtcgca gcgcaaatcc agcagatact gaatcgcctg
    21181 gcgctcttct tcggcgctgt gtttaccatc tgccaatagc aactgccgcc ctttctcttc
    21241 cgccattcgc gcggcatgaa acagtaattc actaaaataa atgccgtgat aaagcgtgtt
    21301 ggtcactacc agccccagcg tctgagtact cttcgccgac agattgcggg ccagcaaatt
    21361 tgggcggtaa ccgctctctt ctaccgcctg aaacacgcga tctttagtct cctggctgac
    21421 gtagccatta cctgaaagca cgcgggaaac ggtcgctttt gaaaccccgg cgcgcttcgc
    21481 cacttccagc atcgtcgtca tcattttcat ccctttacac gcaatcaacg cagtgtactg
    21541 caccgtttgc cgattgtcct tgcgcaatcg gcgggaaaaa tattcaggtg accggtttca
    21601 caaatataaa aaatgaacaa ttaactctct tgcttattta gtgacaacta ttcatgattt
    21661 tgtgaaaccg gtttcctaat tccgtttcag catcggcatt tttccgttac gtcgactgat
    21721 aacaactaca tctaccctac tgataacagg ataaaatccg atggccaaaa attatgcggc
    21781 gctggcacgc tcggtgatag cggcactggg cggcgttgat aacatctcgg cggtcacgca
    21841 ctgtatgacg cgtttgcgct ttgttatcaa agatgaccag cttatcgaca gcccgacgtt
    21901 aaaaaccatc cccggcgtgc tcggcgtggt acgtagtgac aaccagtgtc aggtgattat
    21961 cggcaatacc gtttcacaag cctttcagga agtcgtcagc ctgctgccgg gagatatgca
    22021 gcccgcacag cccgtgggta aacccaaact cacgctgcgt cgcattggtg cagggatcct
    22081 cgatgcgctg atcggcacca tgtcaccgct gatcccggcg attatcggcg gatcgatggt
    22141 caaactgctg gcgatgatcc tcgagatgag cggcgtgctg acaaaaggat cgccgacctt
    22201 aaccattctg aatgtgattg gtgacggtgc tttcttcttc ctgccgctga tggtcgcggc
    22261 atctgccgcc atcaaattta aaaccaatat gtcgctggcg attgccatcg cgggtgtgct
    22321 ggtacatccg agttttattg aactgatggc gaaagcggcc cagggtgaac atgtcgaatt
    22381 tgccctgatt ccggtcaccg cggtgaaata cacctacaca gtgatcccgg cgctggtgat
    22441 gacctggtgc ctgtcatata tcgaacgctg ggtggatcgc attacaccgg cggtgaccaa
    22501 aaacttcctc aagccaatgc tgattgtgtt gattgccgca ccgctggcaa tcctgctgat
    22561 tggcccgatt ggtatctgga tcggtagcgc catttcggcg ctggtttaca ccattcatgg
    22621 ttatctgggc tggctttcag tcgccattat gggcgcgctg tggcctctgc tggtaatgac
    22681 cgggatgcac cgcgtcttta cgccaaccat cattcagacc attgccgaaa ccggcaaaga
    22741 agggatggtc atgccgtcag agatcggcgc taacctgtcg ctgggcggtt catcactggc
    22801 ggtggcgtgg aaaacgaaaa acccggaact gcgccagacg gcgctggctg cggcggcatc
    22861 agccattatg gcggggattt ccgaaccggc gttatacggc gtggcgatcc gcctgaaacg
    22921 tccgcttatc gccagtctta tcagcggctt tatttgcggc gcggttgccg gtatggcggg
    22981 gcttgccagc cactcaatgg cagcgccggg gctatttacc agcgtgcagt tcttcgatcc
    23041 ggcgaatcca atgagcatcg tctgggtgtt cgcggtcatg gcgctggcgg tcatgctgtc
    23101 gtttatcctc acactgttgc tcggcttcga ggatattcct gttgaggaag cgactgccga
    23161 ggcgcgaaag catcagagcg tacaaccgac cgtcgccaaa gaagtaagtc ttaattgagg
    23221 atgaaaatgt cagtatttcc agaaggtttt ttatggggcg gcgcgcttgc cgccaaccag
    23281 tctgaaggtg cgttccgtga aggtggcaaa gggctgacca ctgtcgatat gatcccacac
    23341 ggcgagcatc gaatggcggt gaaactgggg ctggaaaaac gttttcagtt gcgcgatgac
    23401 gagttttatc ccagccatga ggcgacggat ttttatcatc gttataaaga agatatcgcc
    23461 ctgatggcag agatgggatt caaggttttc cgtacctcaa ttgcctggag ccgtctcttt
    23521 ccgcagggcg atgaaatcac gcccaatcag cagggcattg ctttttatcg ttctgtcttt
    23581 gaagagtgta aaaagtacgg tatcgaaccg ctggtcacgt tgtgccactt cgatgtgccg
    23641 atgcatctgg tcaccgaata tggctcctgg cgtaaccgca agctggtgga gtttttcagc
    23701 cgctacgccc ggacctgctt tgaagcattt gatggtctgg tgaaatactg gcttaccttc
    23761 aatgaaatca acattatgtt gcatagcccg ttctccggcg cgggtctggt gtttgaagaa
    23821 ggtgaaaatc aggatcaggt gaaatatcag gccgcgcatc accagctggt tgccagtgcg
    23881 ctagccacca aaatcgccca tgaggttaac ccgcaaaatc aggtgggctg tatgctggcg
    23941 ggcggtaact tctaccctta cagttgcaag ccggaagatg tctgggcggc gctggagaaa
    24001 gaccgggaaa acctgttttt tatcgatgtg caggcgcggg gcgcgtatcc ggcttactct
    24061 gcccgcgtat tccgcgaaaa aggggtaacc atcgacaaag caccgggcga tgatgaaatc
    24121 ctgaaaaaca ccgtcgattt tgtctctttc agctattacg cctcgcgctg cgcctcggcg
    24181 gagatgaacg ccaacaatag cagtgcggcg aacgtagtga aatcgctgcg taacccgtat
    24241 ctgcaagtga gcgactgggg ctggggtatt gatccactcg gtctgcgtat caccatgaac
    24301 atgatgtacg accgttatca gaagccgctg tttctggtgg aaaacggcct cggcgcaaaa
    24361 gatgaacttg ctgccaatgg cgagattaac gatgactatc gcatcagcta tttacgcgaa
    24421 catatccgcg caatgggcga agcgattgca gatggcattc cgctgatggg ctacaccaca
    24481 tggggctgta ttgatttagt ttccgcctct acgggtgaaa tgagcaaacg ctacggcttt
    24541 gtctttgttg accgtgacga cgcaggcaac ggtacgctga cgcgcacgcg taagaaatca
    24601 ttctggtggt ataaaaaagt gattgccagt aatggggaag atttagagta ggtaacagtg
    24661 ccggatgcgg cgtgaacgcc ttatccggcc tacatgtcgc acgaaccatg aaggcccgat
    24721 aagcgcagcg catcgggcaa tttagcattt ggcatcagag ctggttcacc ccatcaagaa
    24781 catccctgtc ctgattcctt aatgaaaaac tactcttctt ccaccgctaa ctgcgcgaag
    24841 ccgccattcc cttcccagcc ttccagtcgt tgataaacgg tttctaccgc atctttaatc
    24901 ggctgagtca tcgggtagta aaagccgacg atatccggct ggatgccgag gaaaatcact
    24961 tcgccaatgt cttctttcaa ctggtcgata aggtagttca acggcatgtt atgggtagtc
    25021 atcataaaca tctcggcgat atcatccggg tcgatgatgc ggatttcgcc ggggtttagc
    25081 cccatatcag tagcgtcaac aatcagtaac cgcgtagggc gcagttcacg gatggcgacg
    25141 atgtcgtttt ccggtgcact accgccatca atcaccaccc agttaccttt cggcgcggcg
    25201 gcgcactttt ccgccagcag cgggccagcg ccatcatcgc ccatcatgct attgccaaca
    25261 cagagtaaaa cgtcagtcac gcagtctcct caccatcaaa tagatggcgt tttcctgatg
    25321 aatatcatgc agcatactta gcagcattgt actccattcc tgctgctgcg aagtttgcgc
    25381 tgcccgggct ttatcgaatg cgttggccag catcggcaca tggttaatgt cgatgacgat
    25441 ctcaccatat ttcggcacgc cttccatttt gcggcgggct tcgctgcccg cctccagagt
    25501 ggcaatccat gccagatatt catcccacgg gcaggtgagc gccgcttcca ggcaatcgat
    25561 aaccccaagg tggtgaccaa tcgccaggct gtaatagacc acctgctgcg cctcggcggg
    25621 cgtggcatcg ttctcatcaa taaatttacg gctcagttga ctgaacacca ccttttcact
    25681 catcggatac gcgcctcttc tacaacatga ttcagatggc tgacaatctc gttcagacgc
    25741 ggatcgtttt ccgcttccag ccagcgtgca acctgttctt cgccctgccc taactgtgtc
    25801 aggaagtcat cggcaatctg acgaccgtaa cgataacctg ccaggcggcg tgcttcgcga
    25861 tccactttca cacgcagcgg ctgcaccata tcgccatgca ggatttccgc cggttgttca
    25921 tcctgctcac ccgggccacg ggcgtgaatt ttctgctcca gcaggccgag cgccattgca
    25981 aagccgtaca gcgtggcggc aggcgttggc gggcaacccg gaatgtagac atctaccggg
    26041 atgattttat ccgtaccgcc ccacacgcag tagagatcgt ggaaaatacc accgctgtta
    26101 ccgcaggcac cgtaggagat acaaattttc gggtccggcg cggactgcca cgcacgcagc
    26161 gcaggggatc gcattgcacg ggtgaccgcg ccggtaaaca gtaaaatatc cgcatgacgc
    26221 ggtgaaggaa cgactttaat gccgaagcgt tctgcatcaa acagcggcga taaagtggcg
    26281 aaaatttcga tttcgcagcc gttgcagccg ccgcagtcca cgcggtaaac gtaggcagaa
    26341 cgtttgattt ttttcagtaa cgacgccttc atgctggcga tggattcatc caccgtcatc
    26401 gggaccggaa tgccgttggc gtcacggggg cctaataaat tgctcatcag atggcctctt
    26461 tcatatggcg agtcagttca atacggtcgg acggcaccag gcatttctgg cgcttacatt
    26521 ccgggcaagt ctcaaagctt tcgcggtggt tttccgcgcg gctgtcacca ttgtgcttaa
    26581 gcagcgcaat ggcgtagtcg atctctttct ggacggcgaa aggacgattg cagacgcgac
    26641 agctgcacag cacaaaacgg gactgttgca ggaaatcttc tttcttccac accgccagtt
    26701 cgtactcttg cgacagtttg atcgctgccg tcgggcagac ttcttcgcag cgtccacaga
    26761 agatgcagcg cccgagatta aactcccacg caagctctcc tgtggcgagg tcagtttcaa
    26821 ccgttaaggc gtttgacggg caggcattga cgcaggccgc gcagccgatg cactgctgcg
    26881 ggttctgctc tggcttacca cggaagtttt tatcaaccgc aatcggctcc agcggataag
    26941 acgaggtcgc cgtgccggtt ttgatgactt ttttgataaa ggtaaacatg gcgattcctt
    27001 atttcagcgg cgagttttta cgctcaatgc tgtaacgctc gagttctttg tacggcacca
    27061 ctttgctctt cttcttacgc acatcgacca cggtcatgcg gtcggtacag gagtagcaag
    27121 ggtccaggct accgataatc agcggcgcat cggaaacggt gttgccgcgc agcatgtagc
    27181 gcagggtcgg ccagttcgcg taggtcgcgg cacggcagcg ccagcggtac agcttctggt
    27241 tgtcgccggt catgctccag tggatatcgt cgccgcgcgg cgcttcggca aagcccagcg
    27301 cgaaacggtg cggaatgtag gtaaagcctt ccaccatcag cgggccgccc ggcaggttat
    27361 ccagaccgta gtcgatcatg ttcagcgcgg tatagacttc attgatacgc actttcagac
    27421 gggaaataac gtcgcagccc tgctcgctgt gcacttccat cggcagcagg ccataaccaa
    27481 caaacgggtg atcggcgcgg gtatcgcgag cgtgaccgct ggcacggacc atcgggccaa
    27541 cgttactgaa gtcgcgggca atttccgggt ccagacgacc aatgccgacg gtgcgctgtt
    27601 ccatgttcgg cgtactcagc agcacatcca ccagctcctg cacttcacga cgcatctgtt
    27661 gcgccagctg gcgggtctgg atcatgtcat ctttcagcag atcgcgacga atcccgccga
    27721 tcaggttcag gccgtaggtt ttacgcgcac cggtaaggat ctctgccatt ttcatggagg
    27781 tttcacgcac gcggaagaac tgcataaagc cggagtcgaa gccggtaaag tgacaggcca
    27841 ggccgaggtt gagcagatgc gagtgcaggc gttccacctc cagcagaatg gcgcggatca
    27901 tctgcgcacg ttctggcacc tgaataccca tcgcgttttc caccgacgtg gtgtaggcgg
    27961 tgctgtgagc aaagccgcag atcccgcaca cacggtcaga gaggaaggtc acttcgttgt
    28021 aacccatacg ggtttccgcc agtttttcca tgccgcgatg gacgtagaac aggcggtagt
    28081 cggcgtcgat aatgttttcg ccatcgacga acagacggaa gtgccccggt tcgtcagaag
    28141 tgacgtgcag cggaccaatc ggcacgacgt tgtttttctt gtcgcccagt tcattgatga
    28201 actcgtaggt ttcagcatcg gtagtcggtg ccggacgctg acgataatcc atgctgtctt
    28261 tacgcagcgg ataaagttca tccggccagt catccggcag caccagacga cgttcatccg
    28321 gcagaccaac cggaatcaaa ccgtacatat cgcgcacttc gcgctcgccc cacaccgccg
    28381 ccggaacgcg cggcgtcacg gacggatact ccggtttgtt ggcgtcaact tcgacgcgaa
    28441 ccgttaccca acacttggtg cccttctcca tcgacagcac gtaataaacg gcgtaatgac
    28501 cattcagttt gcgttcgtcg ttaccaaaca gcaccgacag ccagccaccc tgcttgtagt
    28561 agagaaactc caccacttcc ggcaggtagt tcaccttcac ggtcacggtc agctgatctt
    28621 tggtctgcca ggcgtggtcc agcacgacgc ccggaaatgc ctcattcagc gcggcgagat
    28681 aatgttgacc taatttttct tcagacatgc tcaaactctc tttaatcacg ccgccagcaa
    28741 ggagacgaac gctaaaaatg caaagccaaa cccagcccag gtaatgcgca gagtaatatc
    28801 aagacgcaga cgggccatgc tgttttcgaa cagcgcgata accaggacgc cgacgaccag
    28861 tttgacgatg gcaatcacca gcgccagcag cagcccaccg gcggtgaagg tttccatctg
    28921 tccccacggg ataaatacgc cgacgaacat ctgcagcacc accagctgtt tcaggctgat
    28981 accccatttc atgacgccaa agccgctgcc gctgtattca gagagcgggc cttcctgcag
    29041 ctcctgctcg gcttccgcca ggtcgaacgg cagtttgccc atttcgataa aggtggcgaa
    29101 cgcacaggca caaagcgcca gtaccagcgg gatgctctgg ctcagcggcc agtgataaac
    29161 ggtgtcggtg atgttgctga tgttggtgga accggcaacc tgtgcggcaa cccacagacc
    29221 aagcagcagc atcggttcga ccagcacgcc aagcatcgct tcacggctcg cgccgatagc
    29281 ggtaaacggg ctaccggtat ccagaccaga aatggcaaag aagaaacgcg cgatggcaaa
    29341 gagatacagt aaggtgatta aatcacccag ttgcggcagc ggagaaccga cggtcaccac
    29401 cggcagcgca gtagcgatag tcagcatgac gcccaccatc acatacggcg tcaggcggaa
    29461 cacccagccg gaggcatccg ggccaacgct ctggcggccc agcagtttga aaatgtcacg
    29521 atactcctgc aacacacccg gcccacgacg gttatgcaga cgggcgcgcg ccacgcgggt
    29581 aataccggag agcagcggcg caacggcaaa taacaccagc gcctgaatta acggatataa
    29641 aacactcatt ctcaggctcc tcgtgaaaca ataatcacca ccagtaccgc cagttcaacc
    29701 agcgccatcc ggcggaacag caacgcacta ccttcgcact gccagcccgg caccagcgac
    29761 accggattca gccatttgcg cagtttcagc actggcgcaa acgcctgttt caccggcatg
    29821 gcaaaaccgt gagcggtaat caccattgat ttttcatggt cgtagccgca cacccaggcc
    29881 gcaccgcggg aacgtgacgg caggcggtcg cctttgcaaa tcgccataat gatgaatggc
    29941 agcagcgggc aggcaatcag cagcaatgtg atcattggtt gagaaacggt ggtgttagca
    30001 ggctccagag gcagaggtac agcagcagag agcatcggca gcagccacgg cgcagcaaca
    30061 ccgccaatta cgcagcaaat cgccagtgcc actacgctta cgctcatcag gagcggcgca
    30121 caggtggcgt tttcggcttc tttggtacgc ggcgcgccga ggaacgtgac gccatagact
    30181 ttcgccatac acatcaccgc cagcgcaccg gtaattgcca gacccacagc gagcagcggc
    30241 cccagcagac gggcaacaaa cgcgccgcta ttgctcagtt tgaagaagga ttgatagata
    30301 acccattccc cggcaaaccc gttcagcggc ggcagcgcag ccattgccat taacccgact
    30361 aacatggcga tggagataac cggcattttc ttgccgatac caccgagttt ttcgatatcg
    30421 cgatgaccgg tacggaacca gacgctcccc gctccgagga acagtacgct tttgaacagg
    30481 ctatggttaa gcagatggta cagaccaccg accaggccaa gagcaatcag tgccggttgt
    30541 tcgagcgcga tacccgttac gccagcgccc agccccagca gaataatgcc gatattttcc
    30601 agggtgtggt aagccagcag gcgctggatg ttgtgttcca tcaacgcata cagaccaccg
    30661 acgaacgcgg tgatcatgcc gagcaccagc agcgcgatcc cccaccacag cggtgcatta
    30721 ccgccaagca gtgacagggt taacatgccc agcaggccaa ttttcatgac taccgtagaa
    30781 aacaacgcgg cagctggcgc agaggcgtta gcatgtgcct gcggcaccca gccgtgcagc
    30841 ggaataatcc cggccagcag gccaaagcca atcacaccga gcagccagat atcggaaccg
    30901 agcggcagct gttgcatacg catatccagc aggcgcagat ccagcgtgcc ataacgctgc
    30961 cacagcagcc agcaagcaat cgccagcagc agagtgccaa gacgccccag cgcaaaccac
    31021 agtttgccct ctttgctgtt gctggtaagg aacaccgcac acaaggccat gacttcagcc
    31081 attaccacga acatgccgag gttgctggcg atgacggcgc agacggcggc agccatcaac
    31141 atattgatct gcaagccgtt gcacttcacc tgcgcgtggc gatgccagtc aatgttgtag
    31201 aggctgacaa acagaccgca cagaccgagc gtaatcagcc aaatcgcgtt aagcggagag
    31261 atttgcacat cgtagcttac cagcgacagc gcaccgctca cgccaaccgc gccagtcagc
    31321 acagtaaagc ccgcggctgc cgtatacagg ctaccaaccg cgccgccaat tccggctatc
    31381 cagccgctta gcgccttttg aaaagaaaag agaaatgcca gaacagcggc ggcgacaaac
    31441 cacgccacgc cgctattgat cagggaaatt gcgctcattt agcctctcca ctttgagcct
    31501 gctgaaacaa ggtgagatcg ccaaagtccg tgttaaaggt cagctcacgc ttacgtttgc
    31561 taacgcgggc gatatcggtg ttatccacca gatgcagggc tttggtcggg cacatccgca
    31621 cgcaggccgg accttgttca tcaaagctac aaaggtcaca tttgacggcg atcgcgcgaa
    31681 tacccggcac ccagtcaagc agcgtactga tacgcgccgg agcaggcggt gccggtggcg
    31741 ctttcggggt attggcattt gcaggaatat ccagcggacg gctgccggaa aattcaattg
    31801 cgccaaacgg gcaggcgatg ccgcacagct tgcagcttac gcacaggctt tcattcaact
    31861 gcacggcccc atcaacgcgg gtgatggcgt taaccgggca gaccaccgcg cagggtgcat
    31921 cttcacagtg gtgacagagc tgcggcgcag attctttttc attcagcatc actctcaggc
    31981 gcggcattga ttgcaggccg tgctggcgat gcgtctctga acaggcggcc tcacaagtgt
    32041 ggcagccgat acagagcgtg gagtcagcaa ttacaaaacg attcaccagg cattcctcag
    32101 gtgattgtca tttttgacga aaacatgccg atgaaatgtc attttcgaca ctcatcgaca
    32161 cgcccatccc caaacaggcg taacgcctgc aaaacgggca aagcctcagc tcatgctgcc
    32221 gggctttgtc cctttaccag ttggcttaaa ttcaccggca cattgttttc aatggcggtg
    32281 tataagctgt cgtaaacgcc agcgattttt tcgagatagt gttccagaac ctgttcgcga
    32341 tcgcggatgt tgaccttgcc atcaatcatg ccgtcaatgc tcagttgcgc ctgcgcaatc
    32401 cgctgtttgt cttcgccatc ttttgtttcg acgtaatact cgatggtgtg gctgttaaag
    32461 ccatccgcca gggtgacgta aatacgaaaa tgttcaaaaa ggacgaaaca gagttctttg
    32521 tccggcgcgc agctcatggc gtgatgcagg cgcgctttcg ataacgtgat cccctgaacc
    32581 agcgaattgc agtagatgtg ccactggtcc tgtaggcgac gatgccgctg tgcgatgtaa
    32641 tcggctttct cgcttatttc ccaaatagtc attgtcaggt tacccgttta acagagatgc
    32701 cagctttaag cattttttgt gccaactttt aatttattgt tattaaagag atttttaaga
    32761 taaagatgaa tttcgtcgcc gtgtcgacgt gtcatttcga catcatcgac attattcacc
    32821 gcagggataa tcaacactgg cacaattatt gcttgtagct ggcaatagtt aatgggaggc
    32881 gatatgcacg aaataaccct ctgccaacgg gcactggaat tgatcgaaca gcaggccgca
    32941 aaacacggcg caaaacgcgt aactggggtc tggctcaaaa ttggcgcatt ttcttgtgtc
    33001 gaaaccagct ctcttgcctt ttgttttgat ctggtttgcc gcggcagcgt ggcggaaggt
    33061 tgtaaactgc acctcgaaga acaagaggcc gaatgctggt gtgaaacatg ccaacagtat
    33121 gtgacgctac tgacccagcg cgtccgccgc tgtccacagt gtcatggtga catgctacag
    33181 attgtggcag acgacggttt acagattcgg cggatagaaa tagaccagga gtgagcgatg
    33241 tgtacaacat gcggttgcgg tgaaggcaac ctgtatatcg agggtgatga acataaccct
    33301 cattccgcgt ttcgtagcgc gccatttgcc ccggcggcac gcccgaagat gaaaatcacc
    33361 ggcattaaag cgcctgaatt tacccccagc cagactgaag aaggcgacct gcattacggt
    33421 catggcgaag cgggcactca cgcgccgggc atgagccagc gtcggatgct ggaagtcgaa
    33481 attgacgtgc tggacaaaaa taaccgtctg gctgaacgca accgcgcgcg ctttgctgcc
    33541 cgcaagcaac tggtgctcaa cctggtttcc agccctggtt ccggtaaaac caccctgctg
    33601 acggaaacct taatgcgcct gaaagacagc gttccgtgcg cagttattga aggcgatcag
    33661 caaaccgtga acgatgccgc acgcattcgc gctaccggca caccagcgat tcaggtgaac
    33721 actggtaaag gctgccacct tgacgcacag atgattgccg acgccgcacc gcgtctgcca
    33781 ctggacgata acggtattct gtttatcgaa aacgttggca acctcgtatg cccggccagc
    33841 ttcgatctcg gtgaaaaaca caaagtagcg gtcctttccg ttaccgaagg tgaagacaaa
    33901 ccgctgaaat atccgcatat gtttgccgcc gcctcgctga tgctgctcaa caaagttgac
    33961 cttttgccgt atctcaactt tgacgttgag aagtgcatcg cctgcgcacg cgaagtcaat
    34021 ccagaaattg aaatcatcct tatttccgcc accagcggcg aagggatgga ccagtggctg
    34081 aactggctgg agacacagcg atgtgcatag gcgttcccgg ccagatccgc accattgacg
    34141 gcaaccaggc gaaagtcgac gtctgcggca ttcagcgcga tgtcgattta acgttagtcg
    34201 gcagctgcga taaaaacggt cagccgcgcg tgggccagtg ggtactggtt cacgttggct
    34261 ttgccatgag cgtaattaat gaagccgaag cacgcgacac tctcgacgcc ttacaaaaca
    34321 tgtttgacgt tgagccggat gtcggcgcgc tgttgtatgg cgaggaaaaa taatgcgttt
    34381 tgttgatgaa tatcgcgcgc cggaacaggt gatgcagtta attgagcatc tgcgcgaacg
    34441 tgcttcacat ctctcttaca ccgccgaacg ccctctgcgg attatggaag tgtgtggcgg
    34501 tcatacccac gctatcttta aattcggcct cgaccagtta ctgccggaaa acgttgagtt
    34561 tatccacggt ccgggttgtc cggtgtgtgt actgccgatg ggtagaatcg acacctgcgt
    34621 ggagattgcc agccatccgg aagtcatctt ctgtaccttt ggcgacgcca tgcgcgtacc
    34681 agggaaacag ggatcgctgt tgcaggcaaa agcacgcggt gccgatgtgc gcatcgttta
    34741 ctcgccgatg gatgcgttga aactggcgca ggagaatcca acccgtaaag tcgtattctt
    34801 cggcttaggt tttgaaacca ccatgccgac caccgccatc accctgcaac aggcgaaagc
    34861 ccgcgatgtg cagaattttt acttcttctg ccagcatatt acgcttatcc cgacgctgcg
    34921 cagtttgctg gaacagccgg ataacggtat cgacgcgttc ctcgcgccgg gccacgttag
    34981 tatggttatc ggcactgatg cctataattt tatcgccagc gattttcatc gtccgctggt
    35041 ggtcgctggt ttcgaacccc ttgatctact acaaggcgtg gtcatgctgg tggagcagaa
    35101 aatagcggcc cacagcaagg tagagaatca gtatcgtcga gtggtaccgg atgccggtaa
    35161 cctgctggcg caacaggcga ttgccgatgt gttctgtgtc aacggcgaca gcgaatggcg
    35221 cggcttaggc gtgattgaat cttctggcgt acacctgacg ccggattatc aacgattcga
    35281 tgccgaagca catttccgcc cggcaccgca gcaggtctgc gatgacccgc gcgcacgttg
    35341 tggtgaagta ttaacgggca aatgtaagcc gcatcaatgc ccgctgtttg gtaacacctg
    35401 taatcctcaa accgcatttg gtgcactgat ggtctcctcc gaaggagcgt gcgccgcgtg
    35461 gtatcagtat cgtcagcagg agagtgaagc gtgaataata tccaactcgc ccacggcagc
    35521 ggcggccagg cgatgcagca attaatcaac agcctgttta tggaagcctt tgccaacccg
    35581 tggctggcag agcaggaaga tcaggcacgt cttgatctgg cgcagctggt agcggaaggc
    35641 gaccgtctgg cgttctccac cgacagttac gtcattgacc cgctgttctt tcctggcggt
    35701 aatatcggca agctggcgat ttgcggcact gcgaatgacg ttgcggtcag tggcgctatt
    35761 ccgcgctatc tctcctgtgg ctttatcctc gaagaaggat tgccgatgga gacactgaaa
    35821 gccgtagtga ccagcatggc agaaaccgcg cgcacggcag gcattgccat cgttactggc
    35881 gatactaaag tggtgcagcg cggcgcggca gataaactgt ttatcaacac cgctggcatg
    35941 ggcgcaattc cggcgaatat tcattggggc gcacagacgc taaccgcagg cgatgtgttg
    36001 ctggtgagcg gcacgctcgg cgaccacggg gcgactatcc ttaacctgcg tgagcagctg
    36061 gggctggatg gcgaactggt cagcgactgc gcggtgctga cgccgcttat tcagacgctg
    36121 cgtgacattc ccggcgtgaa agcgctgcgt gatgccaccc gtggtggtgt aaatgcggtg
    36181 gttcatgagt tcgcggcagc ctgcggttgc ggtattgaaa tttctgaatc agcgctgccg
    36241 gttaaacctg ccgtgcgcgg cgtttgcgaa ttgctgggac tggacgccct gaactttgcc
    36301 aacgaaggca aactggtgat cgccgttgaa cgcaacgcgg cagagcaagt gctggctgcg
    36361 ttacattccc atccactggg gaaagacgcg gcgctgattg gtgaagtggt ggaacgtaaa
    36421 ggtgttcgtc ttgccggtct gtatggcgtg aaacgaaccc tcgatttacc acacgccgaa
    36481 ccgcttccgc gtatatgcta ataaaattct aaatctccta tagttagtca atgacctttt
    36541 gcaccgcttt gcggtgcttt cctggaagaa caaaatgtca tatacaccga tgagtgatct
    36601 cggacagcaa gggttgttcg acatcactcg gacactattg cagcagcccg atctggcctc
    36661 gctgtgtgag gctctttcgc aactggtaaa gcgttctgcg ctcgccgaca acgcggctat
    36721 tgtgttgtgg caagcgcaga ctcaacgtgc gtcttattac gcatcgcgtg aaaaagacac
    36781 ccccattaaa tatgaagacg aaactgttct ggcacacggt ccggtacgca gcattttgtc
    36841 gcgccctgat acgctgcatt gcagttacga agaattttgt gaaacctggc cgcagctggc
    36901 cgcaggtggg ctatacccaa aatttggtca ctattgcctg atgccactgg cggcagaagg
    36961 gcatattttt ggtggctgtg aatttattcg ttatgacgat cgcccctgga gcgaaaaaga
    37021 gttcaatcgt ctgcaaacat ttacgcagat cgtttctgtc gtcaccgaac aaatccagag
    37081 ccgcgtcgtc aacaatgtcg actatgagtt gttatgccgg gagcgcgata acttccgcat
    37141 cctggttgcc attaccaacg cggtgctttc ccgcttggat atggacgaac tggtcagcga
    37201 agtcgccaaa gaaatccatt actatttcga cattgacgat atcagtatcg tcttacgcag
    37261 ccaccgtaaa aacaaactca acatctactc cactcactat cttgataaac aacatcccgc
    37321 ccacgaacag agcgaagtcg atgaagccgg aaccctcacc gaacgcgtgt tcaaaagtaa
    37381 agagatgctg ctgatcaatc tccacgagcg ggacgattta gccccctatg aacgcatgtt
    37441 gttcgacacc tggggcaacc agattcaaac cttgtgcctg ttaccgctga tgtctggcga
    37501 caccatgctg ggcgtgctga aactggcgca atgcgaagag aaagtgttta ccactaccaa
    37561 tctgaattta ctgcgccaga ttgccgaacg tgtggcaatc gctgtcgata acgccctcgc
    37621 ctatcaggaa atccatcgtc tgaaagaacg gctggttgat gaaaacctcg ccctgaccga
    37681 gcagctcaac aatgttgata gtgaatttgg cgagattatt ggccgcagcg aagccatgta
    37741 cagcgtgctt aaacaagttg aaatggtggc gcaaagtgac agtaccgtgc tgatcctcgg
    37801 tgaaactggc acgggtaaag agctgattgc ccgtgcgatc cataatctca gtgggcgtaa
    37861 taatcgccgc atggtcaaaa tgaactgcgc ggcgatgcct gccggattgc tggaaagcga
    37921 tctgtttggt catgagcgtg gggcttttac cggtgccagc gcccagcgca ttggtcgttt
    37981 tgaactggcg gataaaagct ccctgttcct cgacgaagtg ggcgatatgc cactggagtt
    38041 acagccgaag ttgctgcgtg tattgcagga acaggagttt gaacgtctcg gcagcaacaa
    38101 aatcattcag acggacgtgc gtctaatcgc cgcgactaac cgcgatctga aaaaaatggt
    38161 cgccgaccga gagttccgta gcgatctcta ttaccgcctg aacgtattcc cgattcacct
    38221 gccgccacta cgcgagcgtc cggaagatat tccgctgctg gcgaaagcct ttaccttcaa
    38281 aattgcccgt cgtctggggc gcaatatcga cagcattcct gccgagacgc tgcgcacctt
    38341 gagcaacatg gagtggccgg gtaacgtacg cgaactggaa aacgtcattg agcgcgcggt
    38401 attgctaaca cgcggtaacg tgctgcagct gtcattgcca gatattgttt taccggaacc
    38461 tgaaacgccg cctgccgcaa cggttgtcgc ccaggagggc gaagatgaat atcagttgat
    38521 tgttcgcgtg ctgaaagaaa ccaacggcgt ggttgccggg cctaaaggcg ctgcgcaacg
    38581 tctggggctg aaacgcacga ccctgctgtc acggatgaag cggctgggaa ttgataaatc
    38641 ggcattgatt taactgcaaa ttgccggaca gatctgcctg tccggcatac tattcacgag
    38701 gttttttcgg acgatatttt tccggcagtt ctggcaccgg acgcttgtca tcgatgagat
    38761 gacgcacggt taagatcgga tgacgccaca gcattctcgg cccggcccaa cgcataatct
    38821 gtttcatctc ttcacgcttt gcaggctggt aacagtgcac cggacactgc ttacaggctg
    38881 gtttctcttc gccgaacaca catttatcca gccgcttttg cgcgtaaaca aacaacgcct
    38941 cgtaatgctc cggctccgct gacgcctgcg ggcatttcgc ttgataaaga tcgatcattt
    39001 ttttaatcgt cagtttttca cgagagatac gcttgccgga catgctgcct ccacctcatt
    39061 aagatgtatt tatattacat cttaatctta aagggcacta tgactctaaa gaagaaaggt
    39121 tcgccaaccg acgcaatttt gcgtacttgc ttcataagca tcacgcaaaa gctgcaaaac
    39181 agcatctttc ccggaaccag catcaagaac tcgccgttcg cttcttcccc tgaaatgatt
    39241 aactccggta tcatgtgcgc cttatgtgat tacaacgaaa ataaaaacca tcacacccca
    39301 tttaatatca gggaaccgga cataacccca tgagtgcaat agaaaatttc gacgcccata
    39361 cgcccatgat gcagcagtat ctcaagctga aagcccagca tcccgagatc ctgctgtttt
    39421 accggatggg tgatttttat gaactgtttt atgacgacgc aaaacgcgcg tcgcaactgc
    39481 tggatatttc actgaccaaa cgcggtgctt cggcgggaga gccgatcccg atggcgggga
    39541 ttccctacca tgcggtggaa aactatctcg ccaaactggt gaatcaggga gagtccgttg
    39601 ccatctgcga acaaattggc gatccggcga ccagcaaagg tccggttgag cgcaaagttg
    39661 tgcgtatcgt tacgccaggc accatcagcg atgaagccct gttacaggag cgtcaggaca
    39721 acctgctggc ggctatctgg caggacagca aaggtttcgg ctacgcgacg ctggatatca
    39781 gctccgggcg ttttcgcctg agcgaaccgg ccgaccgcga aacgatggcg gcagagctgc
    39841 aacgcactaa tccggcggaa ctgctgtatg cagaagattt cgccgagatg tcgctgattg
    39901 aaggccgtcg cggcctgcgc cgtcgcccgc tgtgggagtt tgaaatcgac accgcgcgcc
    39961 agcagttgaa tctgcaattt ggcacccgcg atctggtcgg ttttggcgtc gagaacgcgc
    40021 cgcgcggact ttgtgctgcc ggttgtctgt tgcagtatgc gaaagatacc caacgcacga
    40081 ccctgccgca tattcgttct atcaccatgg aacgtgagca ggacagcatc attatggatg
    40141 ccgcgacacg tcgtaacctg gaaattactc agaacctggc gggcggtgcg gaaaatacgc
    40201 tggcttctgt gctcgactgc accgtcacgc cgatgggtag tcgtatgctg aaacgctggc
    40261 tgcatatgcc agtgcgcgat acccgcgtgt tgcttgagcg ccagcaaact attggcgcat
    40321 tgcaggattt caccgccgag ttgcagccgg tactgcgtca ggtcggcgac ctggaacgta
    40381 ttctggcacg tctggcttta cgaactgctc gcccacgcga tctggcccgt atgcgccacg
    40441 ctttccagca actgccggag ctgcgtgcgc agttagaaac tgtcgatagt gcaccggtac
    40501 aggcgctacg tgagaagatg ggcgagtttg ccgagctgcg cgatctgctg gagcgagcaa
    40561 tcatcgacac accgccggtg ctggtacgcg acggtggtgt tatcgcatcg ggctataacg
    40621 aagagctgga tgagtggcgc gcgctggctg acggcgcgac cgattatctg gagcgtctgg
    40681 aagtccgcga gcgtgaacgt accggcctgg acacgctgaa agttggcttt aatgcggtgc
    40741 acggctacta cattcaaatc agccgtgggc aaagccatct ggcacccatc aactacatgc
    40801 gtcgccagac gctgaaaaac gccgagcgct acatcattcc agagctaaaa gagtacgaag
    40861 ataaagttct cacctcaaaa ggcaaagcac tggctctgga aaaacagctt tatgaagaac
    40921 tgttcgacct gctgttgccg catctggaag cgttgcaaca gagcgcgagc gcgctggcgg
    40981 aactcgacgt gctggtgaac ctggcggaac gggcctatac cctgaactac acctgcccga
    41041 cctttattga taaaccgggc attcgcatta ccgaaggccg ccatccggtg gttgaacagg
    41101 tgctgaatga gccgtttatc gccaacccgc tgaatctgtc gccgcagcgt cgcatgttga
    41161 tcatcaccgg tccgaacatg ggcggtaaaa gtacctatat gcgccagacc gcgttgattg
    41221 cgctaatggc ctatatcggc agctacgtac cggcgcaaaa agtcgagatt ggcccgattg
    41281 accgtatctt tacccgcgta ggcgcggcag atgacctggc ttccgggcgt tcgaccttta
    41341 tggtggagat gaccgaaacc gccaatattt tacataatgc caccgaatat agtctggtat
    41401 tgatggatga gatcgggcgt ggaacgtcca cttacgatgg tctgtcgctg gcgtgggcgt
    41461 gcgcggaaaa tctggcgaat aagattaagg cattgacgct gtttgccacc cactatttcg
    41521 agctgacaca gttaccggag aaaatggaag gcgtcgccaa cgtgcatctc gatgcactgg
    41581 agcacggcga caccattgcc tttatgcaca gcgtgcagga tggcgcggcg agcaaaagct
    41641 acggcctggc ggttgctgct ctggcgggcg taccgaaaga ggttattaag cgcgcacggc
    41701 aaaaactgcg tgagctggaa agcatttcgc cgaacgccgc cgctacgcaa gtggatggta
    41761 cgcaaatgtc tttgctgtcc gtaccagaag aaacttcgcc tgcggtcgag gcactggaaa
    41821 acctggaccc ggattcactg actccgcgtc aggcgctgga gtggatttat cgcttgaaga
    41881 gtctggtgta ataaaaattc ccgatagtct tttgctatcg ggaatattaa cgacaactga
    41941 cgaatcaaat aaaaataccc tgtataatag gaaagcttat tttacagggt aaaaccatgc
    42001 catctacacg ctatcaaaaa atcaatgccc atcactatcg ccatatatgg gtcgttggtg
    42061 atattcatgg tgaatatcag ttattacaat cccgcttaca tcaactctct tttttccccg
    42121 aaaccgactt acttatttct gtcggcgata atattgatcg tgggccggag agtcttgacg
    42181 tcctgcgcct gctaaaccag ccctggttta tctccgttaa aggcaaccac gaagcaatgg
    42241 cgctggatgc gttcgcgacc ggcgatggca atatgtggct tgccagcggt ggtgactggt
    42301 ttttcgattt aaatgattca gagcaaaaag aagctacaga tctgttgctg aaattccatc
    42361 accttccaca tattattgaa atcactaacg acaacataaa atatgtcatc gcacatgcag
    42421 attatccggg gagtgaatat ctctttggta aagaaatagc ggagagcgaa ttactctggc
    42481 ctgttgatcg tgtgcagaaa tcgcttaatg gcgagttaca acaaataaac ggcgctgatt
    42541 attttatatt tggacatatg atgtttgata acattcagac gttcgctaac cagatttata
    42601 ttgataccgg atcgccgaaa agtgggcggc tgtcatttta taaaataagg tagtctcatg
    42661 cttcttctgt gaagcatgag taaccagatg ttattgcagg ccattattca tttttcgcta
    42721 ccagcaaaga gagatcctgc ttcgccagcg cgcgactggc actctccggc aaaccgtcgt
    42781 ctgtaataat ctgatcaaac tcgcttaatg gtaacgccag ccatgtcgcc acctgaccat
    42841 atttcgtcgc atcacagacc aaaactcgct ggcggctggc actggcaatc gcccgtttca
    42901 ccgtgacttt atcttccgct ggcgtagaaa tcccccgcac actccatgac gatgcagaaa
    42961 taaaagcctg atcaatcatc aggctgcgca gcatggtcgc agcggcttcc ccgacacagg
    43021 aacggttttc ccgacacact gcaccgccag tgtgaataat tgtgcaatta ctgttgtcga
    43081 gcaagtagtt cgcaataacg aaatcgtttg tgaccacagt cagtgactcc atgtgaatca
    43141 gatgctgtgc tatcgctaac gtggtcgttc ccgcatccag atagatacaa cttcccggct
    43201 gaacaagact tgccgccagc ttgccaatag ccgctttttg cgtcattgcc agcgcagttt
    43261 ttacctgatg agaaggttca tgcgccacgc gtcccggaga ctggacgcct ccggacacca
    43321 gcacaacggc tccctgctgc tccagttttt gtaaatcccg acgaatggtc atatgtgaca
    43381 cattcattct gtccgttagt tcagcaatac tgacaatgcc tttttcagct accatctcaa
    43441 ggatgatttg gcgacgctct acgggtatca acttttgctc cttcctttgt cctgctgaca
    43501 ttctacgcta tttgcctgcg aaacgtgcgc ggcgcaacta acgcttagtt cacataaaat
    43561 aacacacaat gttaatttat gtgaatcagc tcaccatatc gttatcttcc agcgcttata
    43621 ttcacaatat caaacaaaat atcacttaaa ttaacaagga gagcagatga aaacgggatc
    43681 tgagtttcat gtcggtatcg ttggcttagg gtcaatggga atgggagcag cactgtcatg
    43741 tgtccgcgca ggtctttcta cctggggcgc agacctgaac agcaatgcct gcgctacgtt
    43801 gaaagaggca ggtgcttgcg gggtttctga taacgccgcg acgtttgccg aaaaactgga
    43861 cgctctgctg gtgctggtgg tcaatgcggc ccaggttaaa caggtgctgt ttggtgaaac
    43921 aggcgttgca caacatctga aacccggtac ggcagtaatg gtttcttcca ctatcgctag
    43981 tgctgatgcg caagaaattg ctaccgctct ggctggattc gatctggaaa tgctggatgc
    44041 gccagtttct ggtggtgcag taaaagccgc taacggtgaa atgactgtca tggcctccgg
    44101 tagcgatatt gcctttgaac gactggcacc cgtgctggaa gccgttgccg gaaaagttta
    44161 tcgcataggt gcagaaccgg gactaggttc gaccgtaaaa attattcacc agttgttagc
    44221 gggcgtacat attgctgccg gagccgaagc gatggcactt gcagcccgtg cggggatccc
    44281 gctggatgtg atgtatgacg tcgtgaccaa tgccgccgga aattcctgga tgttcgaaaa
    44341 ccggatgcgt catgtggtgg atggcgatta caccccgcat tcagccgtcg atatttttgt
    44401 taaggatctt ggtctggttg ccgatacagc caaagccctg cacttcccgc tgccattggc
    44461 ctcaacagca ttgaatatgt tcaccagcgc cagtaacgca ggttacggga aagaagacga
    44521 tagcgcagtt atcaagattt tctctggcat cactctaccg ggagcgaaat catgatcaag
    44581 attggcgtta tcgccgatga ttttaccggc gcgacggata tcgccagttt tctggtggaa
    44641 aacggtctac caacggtaca aattaacggt gttccaacag gtaaaatgcc ggaagcaatc
    44701 gacgcactgg tgatcagcct gaaaacgcgc tcctgtccgg tggttgaagc cacacagcaa
    44761 tcgctggcgg ctctgagctg gttgcaacag caaggttgca aacagatcta tttcaaatac
    44821 tgctctactt tcgacagtac ggcgaaaggt aatatcggcc cggttaccga tgcattaatg
    44881 gatgctctcg acacgccgtt tacggtcttc tctccggccc tgccggtcaa cggacgtacg
    44941 gtttatcagg ggtatttgtt cgtaatgaat caactgctgg ccgaatccgg gatgcgccat
    45001 cacccggtaa atcccatgac cgacagctat cttccccgtc tggttgaagc gcaatccaca
    45061 gggcgctgcg gcgtcgtttc ggcacatgtt ttcgaacaag gtgtggatgc cgttcgtcaa
    45121 gagctggctc gcttacagca agagggctac cgctacgcgg tgcttgatgc gctgaccgaa
    45181 caccatctgg aaattcaggg agaagccttg cgcgatgccc cactggtaac gggcggttct
    45241 ggtctggcga ttggcctggc ccggcagtgg gcgcaagaaa acggtaacca ggctcgcgaa
    45301 gcagggcatc cgctcgctgg gcgcggcgta gtgctctccg gttcatgctc tcaaatgacc
    45361 aaccgccagg tggcacatta ccgtcaaatt gcaccagccc gtgaagttga tgtggcacgc
    45421 tgcctctcaa ccgaaactct ggccgcttat gcacacgaac tggcagagtg ggttctgggc
    45481 caggaaagtg tacttgctcc actggttttt gccaccgcca gcactgacgc attggcagca
    45541 attcaacagc aatacggtgc acaaaaagcc agtcaggcag tagaaactct attttctcaa
    45601 ctagcggcgc ggttagcagc ggaaggcgtg acacgcttta ttgtcgcagg cggtgagacc
    45661 tccggcgtag tcacacagag cctgggcata aaagggtttc atattggccc aaccatttcc
    45721 cccggcgtgc cgtgggtaaa cgcactggat aagcctgtct cactcgccct taaatctggc
    45781 aacttcggtg atgaagcttt tttttcacga gcccaaagag agtttttatc atgagcgatt
    45841 tcgcaaaagt agagcagtct ttgcgagagg agatgacgcg gattgccagt tcattctttc
    45901 agcgcggcta tgcaaccggt tcggctggca atctgtcgct gcttttacct gacgggaatt
    45961 tactggcgac accgacaggt tcatgcctgg gcaatctcga tccgcagcgg ctttccaaag
    46021 tcgccgcgga tggcgaatgg ttaagtggtg acaaaccctc gaaagaggtg ctctttcatc
    46081 tggcgctgta tcgcaacaat ccgcgctgta aagcggtggt gcatttgcac agcacatggt
    46141 cgacggcgct ttcctgcctg caagggctgg acagcagcaa cgttattcgt ccgttcacac
    46201 catacgtggt gatgcggatg ggaaatgtcc cgctggtgcc ttattaccga ccgggcgata
    46261 aacgcatcgc acaggatctg gcggaactgg cagcagacaa tcaggctttt ttactggcaa
    46321 atcatggccc agtggtttgc ggtgaaagcc tgcaagaagc cgccaacaat atggaagagc
    46381 tggaggaaac ggcaaagctg atttttattc tcggtgaccg cccgatccgt tatctgaccg
    46441 caggtgaaat tgcggaatta aggagttaat gcaatgcctc gttttgcagc taatttatcc
    46501 atgatgttca ccgaagtgcc ttttattgaa cgcttcgccg cagcgcgaaa agccgggttc
    46561 gatgctgtgg aatttctgtt tccctatgac tactccaccc tgcaaatcca aaagcaactg
    46621 gagcaaaacc atctgacact ggcgctgttc aataccgctc ccggagatat taatgcgggg
    46681 gaatggggat tatccgccct tcccggacgt gagcacgaag cacacgcaga catcgacctg
    46741 gcactggaat atgcattggc gctcaattgt gaacaagtcc atgtgatggc aggcgtcgtg
    46801 cccgctggcg aagacgctga acggtaccgg gcagtattta tcgataatct ccgctacgct
    46861 gccgaccgct ttgcgctaca cggcaagcga atattagttg aagcactcag ccccgacgtt
    46921 aagcctcatt atctcttctc cagccagtat caggcactgg ctattgttga agaggttgcg
    46981 cgagataacg tgtttattca actagatact tttcatgcgc aaaaagtaga tggcaacctg
    47041 acgcatttaa tccgcgacta cgctgggaaa tatgcgcacg tacaaattgc cggactacct
    47101 gatcgacatg aaccggacga tggagaaatc aactatccgt ggctgttccg cctgttcgat
    47161 gaggtgggat atcagggctg gatcggttgt gaatataaac ctcgtggcct caccgaagaa
    47221 gggcttggct ggtttgacgc ctggcgctaa ttcgttaaat ccctaattac aacgtaccca
    47281 tacatccccc catctacgga tggggtaggt taactataac tttcagacag ggtttcccat
    47341 gtccacaatt acattgttat gcattgcgtt agctggcgta atcatgctgt tgctgctggt
    47401 catcaaggca aaggtacaac cattcgttgc tctgctcctc gtcagcctgt tagtcgcact
    47461 tgcggcgggt ataccggcgg gcgaagtggg taaagtgatg atcgccggga tgggcggtgt
    47521 gcttggttcc gtcactatta ttattggtct gggcgctatg ctggggcgta tgatcgaaca
    47581 ctctggtggt gcagagtcac tggctaatta tttcagtcgc aagttaggtg acaaacgaac
    47641 tatcgctgcg ctgactctgg cagcgttctt cctcggtatt cccgtcttct ttgatgtcgg
    47701 ctttattatt cttgcgccaa tcatttacgg ttttgccaag gttgccaaaa tatcgccact
    47761 caaatttggc ctgcctgtcg ctggaatcat gctaactgtt catgtggcgg taccgccgca
    47821 tccaggccct gtcgccgcag cggggttact ccacgcagac atcggctggc taaccatcat
    47881 cggtattgcg atttctattc ccgtagggat tgttggctac tttgcagcga aaataatcaa
    47941 tacgcgccaa tatgcgatgt cggtggaagt actggaacag atgcaactgg ctccggccag
    48001 tgaggaaggc gcaacaaaat taagcgataa aataaatcca ccgggcgtcg cgctggtcac
    48061 ctcgctaatt gttattccta tcgcgattat catggcgggt acggtttccg caacactgat
    48121 gccgccttcg catcccctgc ttggtacgct acagctgatc ggctcaccaa tggtagctct
    48181 aatgattgcg ctggtgctgg cattctggtt attggcttta cgtcgcggct ggagcttaca
    48241 acacaccagc gacattatgg gctcagccct tcccactgcg gcggtagtga ttttggttac
    48301 tggtgctgga ggggtatttg gcaaagtgct ggtggaatcg ggcgtcggca aagcccttgc
    48361 caatatgcta caaatgattg acctgcctct gttaccagcc gcatttatta tttcactggc
    48421 tctgcgtgca tcgcaggggt cagcaaccgt agcaatcctg acaaccggcg ggttactctc
    48481 agaagcggtg atgggattga atccgattca gtgcgtattg gtgacgctgg cagcctgctt
    48541 tggtgggctt ggcgcgtcac atattaatga ctcagggttc tggattgtga ccaaatatct
    48601 ggggttgtcg gtagcagacg gtctgaaaac ctggacagtg ttaacgacca ttctcggttt
    48661 taccggattc ttaattacct ggtgcgtatg ggcggtaatt tgaccttaat aaaaaggtcc
    48721 gatgggcatc ggacctttta tttaacgctt accttccacc agcagcggcg ggatgctcgg
    48781 caccattggc gcgtcatcaa tatctttctg cgtcatgcgg aacgcttcgg gataatgttc
    48841 gcggctggta cggcgcagcg gttcggtatc gcgccaggta taaaggcaat gctggcactg
    48901 atataccgtc cagacatctt tcaccggcga tttcgccatc acttcaatct gttcatcggc
    48961 acaacgtgga caaatcatct tcttctcctt atttacgtgc agccagcata gcggtcagtt
    49021 tttcagccca ggctttggtt tccggtaaat ccaccaccgg ttggctgtag tgaccacggt
    49081 tgtccggggc gacaggcgta gtggcgtcga taatcagctt gtcggtgatc cccgcagggc
    49141 ttgagcctgg atcgagttcc agcacggaca tattcggcaa ctgcaccaaa tcccctgccg
    49201 ggttcacttt cgaggagagc gcccacatca cctgcggcag gttgaacggg tcaacgtctt
    49261 catcgaccat aatcaccatc ttcacgtagc ccagaccatg cggcgtggtc attgcgcgca
    49321 ggcccaccgc gcgggcaaag ccgccgtagc gttttttggt ggagataatc gccagcaggc
    49381 catgggtgta catggcgttt accgcctgca cttccgggaa ctcggctttc agctgctgat
    49441 acagcggcac gcaggtggct ggccccatca ggtagtcgat ttcggtccac ggcataccga
    49501 ggtacagcga ttcgaaaatc ggcctggtgc ggtaagagac tttatcgatg cgcaccacgg
    49561 tcatgttacg cccgccggag tagtgcccgg taaactcacc gaacggccct tcgatttcgc
    49621 gtttacggct ttcgataacc ccttcgagga tcacttctga accccacggc acatcaaaac
    49681 cggtcagcgg ggcggtggcg atcgggtacg ggctttcacg cagcgcgcct gccatttcat
    49741 actcagactg atcgtatttc agcggcgtgg cccccatcag cgtgatgatc ggatcgttac
    49801 cgagcgtgat cgcaatcggc agatcttcac cgcgctcttc tgctttatgc agatgcaggg
    49861 cgatatcgtg catcggcacc ggttgcaggc cgagcttacg cttgcccttc acttccatgc
    49921 ggtagatgcc gacgttctgc ttgccgaagt tatctgggtc gagcggatcg cgggaaacca
    49981 cgcaggcttt gtcgagatag aaaccgccat cgccatcgtt taaacgaaac agcggcagga
    50041 tatcgaacag gttaatctct tcgccatcga cggtgttctg cgcccaggct ggattggcgc
    50101 ggcgctccgg ggcaatcggg aagttatccc agcggcggat aaactcatca atctgctttt
    50161 tgaccggggt gtttggtggc aggccaaggg aaatcgcgtg gttctgccag gaaccgatgg
    50221 tattcatcgt cacgcgggca tcggtaaagc cgcgaatatt atcaaaccac agcgcgggcg
    50281 cgccgtcgcc gatacgcccg gtggcgttag ctgctgctgc cagatccggc tcagcgttca
    50341 cctcttcgct gattttcagt aactggccgt ggtcatcaag cgcctgtaaa aagctgcgta
    50401 aatcatcaaa tgccattatt cattctcctg agaaaaattc cgggcctgcg gcaatccttg
    50461 ccagcgcctg gcatggggat gttcgaggcc aaattgatcc agcacgcggg ctaccacatg
    50521 gtggacaatg tcatctaccg tttcgggatg gttataaaag gcaggcatcg gcggcaccat
    50581 cgccacgccc atgcgtgaaa gtgcgagcat attttcgaga tggatggtgc taagcggcat
    50641 ttcacgcggc accagcacca gtttgcggcc ttctttgagc acgacgtccg ccgcgcgccc
    50701 taccaggcca tcggcgtaac cagcgcggat accggcgagc gttttcatac tgcacggaat
    50761 aacgatcatg ccgtcggtac gaaaagaacc ggatgagatg atcgccgcct gatccgccgg
    50821 gttatggctg aagtctgcga gggcagcaac atcgtgagcg ctgtaaggcg tttctagttc
    50881 aatggtggtt ttcgcccact tcgacatcac cagatgagtc tcgacattcg gcatatcccg
    50941 cagcgcttgc agtaatgcca caccaagagg cgcaccggta gcccctgtca tcccgacgat
    51001 cagtttcatt gcttatcctc ttaattgttc gtatacgaac gttattatta acatactcct
    51061 tcatttccac agcggcaagg attgaaaagt aacaacatct tcttcgtcac taaaaaaccg
    51121 ctatgatagc gacagagaat tagcccggag tttacatggc gttacgaaat aaagcgttcc
    51181 atcagttacg acagcttttt cagcagcaca cggctcgctg gcagcacgag ttacctgacc
    51241 tgaccaaacc acagtacgcg gtgatgcgcg ccattgctga taaacctggt atcgaacagg
    51301 tggcactgat agaagcagct gtcagcacca aagcaacgtt agcagaaatg ttggcaagaa
    51361 tggaaaatcg tggcttagtc agacgtgaac atgaccccgc tgataagcgg cgacgctttg
    51421 tctggttgac tgccgaaggc gaaaagatac ttgctgcggc gatacccatt ggtgacagcg
    51481 tggatgagga atttttgggg cgtttgagtg gagaagagca ggagctgttt atgcagctgg
    51541 tgcgcaagat gatgaacgca tagggggcaa atttccggat gcgacgctat cgcgtcttat
    51601 ccagactaca aatacaccga ctcaccaacc gaaagaaaaa aggccagcct cgcttgagac
    51661 tggcctttct gacagatgct tacttactcg cggaacagcg cttcgatatt cagcccctgc
    51721 gtttgcagga tttcgcgcaa acggcgcagg ccttcaacct gaatctggcg aacacgttca
    51781 cgggtgaggc caatttcacg acctacatct tccagtgttg ccgcttcgta ccccagcaaa
    51841 ccgaatcgac gtgccagcac ttcacgctgt ttggcgttca gctcgaacag ccatttgacg
    51901 atgctctgct tcatatcgtc atcttgcgtg gtatcttccg gaccgttctc tttttcatcg
    51961 gccaggatgt ccagcaacgc tttttcggaa tcaccaccca gcggggtgtc taccgaggta
    52021 atgcgctcgt taagacgaag catacggctg acgtcatcaa ctggcttatc cagttgctct
    52081 gcgatctctt ccgcacttgg ttcatggtcc agcttatggg acaactcacg tgcggttcgc
    52141 aggtaaacgt tcagctcctt tacgatgtga atcggcaaac gaatagtacg ggtttggttc
    52201 ataatcgccc gttcaatcgt ctggcgaatc caccaggttg cgtatgttga gaagcggaaa
    52261 ccacgttccg ggtcaaactt ctctaccgcg cggatcagcc ccaggttgcc ctcttcgata
    52321 aggtccagca acgccagacc acgattgcca taacggcggg caatttttac caccagacgc
    52381 aagttactct cgatcatccg gcggcgagag gcgacatctc cacgcagtgc gcgacgcgca
    52441 aaataaactt cttcttcggc cgttaacagt ggtgaataac caatctcacc aaggtaaagc
    52501 tgagtcgcgt ccaacacacg ctgtgtggct ccctgcgata acagttcctc ttcggccaaa
    52561 tcgttatcac tgggttcctc ttctactaag gccttttcgt caaaaacctc aactccgttc
    52621 tcatcaaatt ccgcatcttc atttaaatca tgaactttca gcgtattctg actcataagg
    52681 tggctcctac ccgtgatccc ttgacggaac attcaagcaa aagcctggtt ccgccgattt
    52741 atcgctgcgg caaataacgc agcgggttta cggatttccc cttgtaacga atttcaaaat
    52801 gcaagcgtgt tgaactggtt ccggtgctac ccatggttgc tattttttgc cccgccttca
    52861 cttcttgttg ttcccggacc agcattgtgt cgttatgggc gtaggcactc aggtaatcat
    52921 cattatgttt gatgataatc agattaccgt agccgcgcag cgcgttaccg gcataaacaa
    52981 cgcggccatc tgcggtcgcg ataattgcct gtcctttgct gcctgcgata tcaatcccct
    53041 tgttgccccc ctcagaagcg ccaaaggttt cgatcacttt gccctcagtc ggccagcgcc
    53101 aggtggagat aggcgtactg gttgatgtac tgctgacagt cggctcggtt gtgcttgctg
    53161 ttggtaccgt tacaggcgct gtgaccgtgg tcgcagttgg cttgttgttc ggcaacattt
    53221 tgttagcact ctgttcaccc gaagactcag aatacgtaat tgtcggttgc gacgcaacag
    53281 caacggtgga attttgtgca ggcttgatca caactccttg ctctgctgca tcggcctggg
    53341 taatggcatt tccgccagtg attggcgtac cggaagcatt acccacctgt aaggtctgac
    53401 cgacgttcag cgcgtatggt gcctgaatat tgttgcgctg agcaaggtca cggaaatcgt
    53461 tgccagtaat ccaggcgata tagaaaagtg tgtcgccttt tttcacggta taggtactgc
    53521 cgctataact gcctttcgga atgttcccat actgacggtt atagacgatg cgtccgtttt
    53581 ccatctgtac cggctgctga gctactggct gtactggctg tactggctgg atttgcggtt
    53641 gttgagtagc ctgaatttgt ggctgctgta ccggctgaat ttgcggttgc tgggctgtag
    53701 acgtcgtccc cattttcggc ggcggcgtaa tcaacatacc agaattggta tttgcaggcg
    53761 cattgccatt aacggagctg accggtgccg gtggatttga agtgtcagaa cagcctgcca
    53821 gccatagcga aaccagtgac aaagccgcaa tgcggcgaac ggtgaatttt gggcttcccg
    53881 cgctcattta tcccccagga aaaattggtt aataaccagt gacataatta ccgtgcaagg
    53941 caccctactg aacactggaa aagatgttca cgatacgctg atctgcggca aaataaccag
    54001 gaaaaatcca ggtatttcct cacgttttaa gccagctcac ccttcactaa agggacaaag
    54061 cgcacggcct ccacggtatc gataataaat tcgcctcccc gacgacgcac ccgtttcaaa
    54121 tactggtgct cctcccctac gggtaagacg agaatcccgc cttcgtccag ctgcgtcatt
    54181 agcgcagttg gaatttccgg cggtgccgcc gtaacaatga tagcgtcaaa cggcgcgcgt
    54241 gcctgccaac cttgccatcc atcgccatga cgggttgaaa cattatgtaa atcaagattt
    54301 ttcaggcggc gacgcgcctg ccactgcaaa cctttaatcc gttcgaccga gcaaacatgc
    54361 tggacaagat gcgccaggat tgccgtttga tatcccgaac cggtgccaat ttccagcacc
    54421 cgcgactgcg gcgtcagctc gagtaattcg gtcattcgcg ccaccatata cggctgcgaa
    54481 attgtctgcc cctgacctat cggcaaggcg atattgtccc aggctttttg ttcaaacgct
    54541 tcatcaacga atttttcacg cggcacggca gcaagtgcat tcagcacctg ctcatcctga
    54601 ataccttgcg cacgtaattg atccagaagt gcttgtacgc gtctgcttac cattgcgtgc
    54661 caactcccac gctgtttaac cagtctgaaa ccacatcttg cgcgctatgc gcagttaaat
    54721 ccacatgcag cggcgtgatg gagacatagc cctcatctac cgcagcaaaa tcggtccccg
    54781 gaccggcatc acatttaccg cccggcgggc caatccagta cagcgtattg ccgcgcggat
    54841 cttgctgcgg gatcacctga tctgccggat gtcgtgtacc gcagcgcgtc acgcgaatac
    54901 ctttgatttg atccaagggt aaatccggaa cgttaatatt aagaatacgc ccggtgcgca
    54961 acggctcttt acacagtgcg cgcaaaattg aacaggttac cgccgcggca gtgtcgtaat
    55021 gtttatgccc gtcaagcgag acggcaagcg ccggaaaacc taaatgacgg ccttccatcg
    55081 cggcggctac cgtaccggaa taaataacat catcccccag attcggcccg gcgttaattc
    55141 cggacacaac aatgtccggg cgcggacgca tcagagcatt cacgccaaga tagacgcaat
    55201 cggtcggggt tcccatttgc acagcaatat caccattttc aaaggtaaac gtgcgcaggg
    55261 aggattccag tgtcagagaa tttgaagcgc cgctgcggtt acgatcgggg gcgaccacct
    55321 gaacgtcagc aaactcacgc aaggctttcg ccagcgtttg tataccgggt gcatgtaccc
    55381 cgtcatcatt actcagcaat atgcgcataa tcacctgttg tgttgataag ttccctgaca
    55441 acgctggttg caaaactacc cgccggaagc cagaaacgga tctctacggt gacgtcatcc
    55501 caccaattcc agcttaattg ttgcggatac agcagcatcg ctctgcgcgc ggcttcaact
    55561 ttttcgcgca ccagtaaagc ttgtaattca gtttctgcgg caacagctgc ttgttcgaat
    55621 gccagcgctt cacgctgagt tccccattcg ccactgcccg gcaatgcggc ggttatcatc
    55681 agctctttat cgttaacgcg acgctgtaat tccgccagtt cttcggtggt tgcgacaaac
    55741 cagctaccac gtccggctaa ttgtagcgca tcgccgtcaa caacttgatt aacgtctgct
    55801 tttttgaggc gctcagcaac aatctgatta aacaacgcac tgcgggctgc cgacaaccaa
    55861 aaactccgtt tattgcgatc gcgcaccgga gtattggttt gcgcccagcg ctgcgccccc
    55921 tgcaagttgc taccgccaat cccaaaacgt tgggcaccga agtagttcgg tacacctttt
    55981 acgcaaatat cgatcagacg ttgttcaacg tcatcgcgat tgctcacttc gcgcagaacc
    56041 agggtaaagg cgttaccttt cagcgcgcct aaacgcagct tgcgcttgtg ccgcgcatac
    56101 tccagcacct ggcagccttc cagttgaaag gcgctcagat cgggcatttc cttgcctggc
    56161 acgcgagcgc ataaccactg ttccgtaaca gcatgtttgt ctttttgccc agcgaagctg
    56221 acttcacggg catgaatttt caggaatttc gccagtgcat ccgccacaaa acgggtattg
    56281 cagccgtttt tgaggattct aaccagaata tgctcacctt caccatcagg ctcaaagccc
    56341 aaatcttcca ccaccacaaa gtcttccgga ttggctttca gcagcccggt gccttgcggt
    56401 ttaccgtgga ggtaagtgag attatcaaac tcaatcattt tgttgcctta atgagtagcg
    56461 ccaccgcttc acaggcaatc ccttccccac gtccggtaaa tccaagtttt tccgtagtag
    56521 tggctttcac gttaacatca tccatatggc agccgagatc ttcggcaata aacacgcgca
    56581 tttgtggaat gtgcggcaac atcttcggtg cctgagcgat gatagtgaca tcgacgttgc
    56641 ccagggtata ccccttcgcc tgaatacgac gccaggcttc gcgtagcagc tcgcggctgt
    56701 cggcaccttt aaatgccgga tcggtatccg ggaacagctt gccgatatcc cccagcgccg
    56761 ccgcgccaag caatgcatcg gtcaacgcat ggagcgccac gtcgccatca gaatgcgcca
    56821 gcaatccttt ttcgtaagga atgcgtacgc caccaatgat aattgggcct tcaccgccaa
    56881 aggcatgtac gtcaaaaccg tgtccaattc gcattatgta ttctcctgat ggatggttcg
    56941 ggtgaggtaa aactcggcca gtgccaaatc ttccgggcgc gtgactttaa tgttatccgc
    57001 acggccttcg accaactgag gatggaatcc gcaatattcc agcgccgagg cttcgtcggt
    57061 aatagtcgcg ccttcattta gagcgcgcgt cagacagtca tgtaacagct cacgagggaa
    57121 aaattgcggc gtcagcgcgt gccataagcc gttgcgatca acggtatgag caatggcatt
    57181 tttgcccggt tcggcacgtt tcatcgtatc gcgcactggt gcggctagga tccctcccgt
    57241 gcggctggtt tcgctcaacg ccaacaatcg cgcgaggtca tcctgatgca gacaaggacg
    57301 agcggcgtca tgcaccaata cccactgcgc gtcgccagcg gctttcagac ctgccagcac
    57361 ggaatcggca cgctcatcac cgccatctac aacggtgatt tgcggatgat tcgccagagg
    57421 aatttgtgca aaacggctat cgccaggact tatggcaatg acgacacgtt tcacccgggg
    57481 atgcgccagc agcgcatgca ccgagtgttc aagaatggtt tgattaccga ttgagagata
    57541 ttgcttagga cattccgttt gcattcgacg gccaaatccg gccgccggaa ccacggcgca
    57601 aacatccaaa tgagtggttg ccatgttaat tcccgggctg atttatcgat tgttttgccc
    57661 cgcagactgt gcgcgcttcg acgcgtcagg caccagacga taaaaagttt cgcccggcct
    57721 ggtcatgctg agttcattac gcgcacgctc ttcgagcgcc tcctggccgc cattgagatc
    57781 gtcaatttcg gcaaaaagtt gatcgtttcg cgctttaagt ttcgcgtttg tagcttgctg
    57841 tgccgccaca tcatcattga cgcgggtata gtcatgtata ccgttcttac cgaaccacag
    57901 cgaatactgt agccagacca gaatagccag caacagcagc gttagtttac ccatcctgcc
    57961 ccctgaaaaa cggcatcatc atcccatgca tccgaagacg actctacatc ctctgttggg
    58021 gataccgcga caacgcgggc aaatgtacca catttgtcca ttgttacgta tacccagggc
    58081 gtgcaaaaca taatctcatt attagttacg gtttgaatta tgaacagagg agacgggaaa
    58141 gtacaaatta gcccagtagc cacataaaca gtgcgccaaa cataatgcct actgtcacca
    58201 gggtgaaaac aatactgtag cgtagctttc cgtccatcaa tgaatgcagc gcaatcccca
    58261 ccactaccgc gacgggcatc agcgccagaa agaaaggcca ggtgtagata aagaagaaca
    58321 gcgtgttaga gccataaatc aacatcggca tcgccagcgc aaataaccag gagataaaac
    58381 cgaccacggc accaggcagt gaccatgtgg tttcttcatc ctcagtaagg ctgtcgttat
    58441 ttgttagtgt aatgttatgg ctattacgca tatttgatcc tgttactttg acgaaccggg
    58501 catggaaacc cggtggtgtc tcaggatctg ataatatcgt tctgtctcaa cagatctaat
    58561 aattgctgta ccaaatttgt tactaattgt tcaccattga gatgaatttc tgccgattca
    58621 ggcgcttcgt aaacggaatc tattcccgta aagttgcgca gttcaccggc acgcgctttc
    58681 ttatataagc cttttggatc gcgggcttcg caaatcgcca gcggcgtatc gacaaacact
    58741 tcgataaagc gcccttctcc tacgcgttcg cgaaccatct ggcgttcggc gcggtgtggc
    58801 gagataaatg cggtcagcac taccagtccg gcttcaacca tcaaattcgc cacttcaccg
    58861 acgcgacgga tattctcttt acgatcggca tcgctaaaac cgagatcgct gcataatccg
    58921 tggcgaacat tatcgccatc cagcagatac gtactgacgc cgagtttatg taacgcctcc
    58981 tccagcgccc cggcgaccgt tgatttaccg gacccggaga ggccggtaaa ccacagcact
    59041 acaccacgat gaccgtggtg tagctcgcgt tgttgcacag tgaccggatg gctatgccag
    59101 acgacgtttt cgtcatgcag cgccattatt tatcccccag caaatcgcgc gcgccccagt
    59161 gcggaaagtg gcgacgaacc agagcattca attccagttc gaatgcactg aattcagatg
    59221 gcgcagcagt tgcctggcta actggctcgt gcaccatacc ggcacccacg gtcacattgc
    59281 tcaggcgatc gataaaaatc agcccacccg tcaccggatt ttgttgataa cgatctaaca
    59341 ccagcggctc gtcaaaagtg agatccacga ggccgatccc attcagtggc aggttttcaa
    59401 cttcacgctg ggtaaggtta ttaatatcaa cctgatagcg aatgccatca atacgcgcgc
    59461 gcgtcttctt accggcaatt ttgatgtcgt aactctggcc cggggaaagc ggctgttccg
    59521 ccatccatac cacatccacc gacgcgctct gcaccgccgg taacgcttcg tctgccgcca
    59581 gcagcagatc gccacggctg atgtcgatct catccgtcag caccagggtg atcgcttctc
    59641 cggcaaaggc ttcttcgcga tcaccatcaa aagtcacgat ccgcgcgacg tttgattcca
    59701 caccagaggg cagcactttg acacgttgcc cgacttccac gcgaccggat gccagcgttc
    59761 cggcgtagcc acgaaaatcg agattcgggc gattaacgta ctgcaccggg aagcgcattg
    59821 gctgagcatc caccactcgc tggatctcca cggtttccag cacttcgagc agtgtcggac
    59881 cgctgtacca cggcatactt tcactttgcg aagccacgtt gtcgccttcc agcgcagaga
    59941 gcggcacaaa gcgaatatcc agattgccag gtaactgttc ggcgaaagtc aggtagtctt
    60001 cacgaatgcg ggtgaatgtc tcttcactgt aatccaccag atccattttg ttgatcgcta
    60061 cgaccagatg tttgatcccc agcagcgtgg agataaaact gtgacgacgg gtttgatcga
    60121 gcacgccttt acgggcatcg atcagtaaga tcgccagctc acacgttgag gcgccggtcg
    60181 ccatattgcg ggtatactgc tcgtgcccgg gggtgtcggc gataataaat ttacgcttct
    60241 cggtagagaa atagcggtag gccacatcaa tagtgatgcc ctgttcgcgc tcagcttgca
    60301 ggccgtccac cagcagagcc agatccagtt tttcgccctg ggtgccgtga cgcttactgt
    60361 cgttatgcag cgatgagagc tgatcttcgt agatttggcg ggtatcgtgc agcaggcgac
    60421 caatcagggt acttttgccg tcatcgacgc taccacaggt cagaaaacgc agcaggcttt
    60481 tatgttgttg cgcaatcatc caggcttcga cgccgccttc attagcgatt tgttgtgcaa
    60541 gtgcggtgtt catcttaaaa atacccctga cgttttttca gctccataga ccccgcctgg
    60601 tcgcggtcaa tcacgcggcc ctgacgttca ctggtggtgg aaaccagcat ctcttcgatg
    60661 atctccggca gtgtttgtgc atttgactcc accgcaccgg tcagcggcca gcagcccagc
    60721 gtacggaaac gcaccatccg ttttttaatc acttcgcccg gttgcaggtc gatacggttg
    60781 tcatcaatca tcatcaacat accgtcgcgt tccagaaccg gacgttccgc agcgagatac
    60841 agcggcacaa tgtcgatatt ttccagccag atgtattgcc agatatcctg ctcggtccag
    60901 ttagagagcg ggaagacgcg gatgctttcg cctttgttaa tttgcccgtt gtagttgtgc
    60961 cacagctccg ggcgctgatt tttcggatcc cagcgatgga cgcggtcacg gaaagagtag
    61021 attcgctctt tagcgcggga tttctcttcg tcacggcgcg caccaccgaa ggcggcatca
    61081 aaaccgtatt tgttcagcgc ctgtttcagg ccttcagttt tcataatatc ggtatgtttc
    61141 gcgctgccgt gcacgaatgg attaatcccc atcgccacgc cttccgggtt tttatgcacc
    61201 agcagctcgc agccgtaggc tttcgccgta cgatcgcgga actcatacat ctcgcggaat
    61261 ttccagccgg tatcgacatg cagcaacggg aaaggcagcg tacctggata aaacgccttg
    61321 cgcgccagat gcagcatgac gctggaatct ttaccgatag agtagagcat caccggattt
    61381 gagaattctg ccgccacctc gcgaataatg tggatgcttt ccgcctccag ttgccgcagg
    61441 tgagtaagtc gtatttgatc cataaccgtt cctttgcaat accgctattt tcttgccatc
    61501 agatgtttcg actataggga gcgtaagaga acgaatgaaa ttaccaatta gaatgagtag
    61561 ttccttaacg gaataacgat ttggcaaagc taatatcaaa aagtgcttaa ggcaccggat
    61621 ttcgggcgtt taggaagatt tgaaattgtt ttagcgcagc ggcagtttca tactatggcg
    61681 gtaaaaaaat ttgcatggta tttaaggact cactatgttt tccgcattgc gccaccgtac
    61741 cgctgccctg gcgctcggcg tatgctttat tctccccgta cacgcctcgt cacctaaacc
    61801 tggcgatttt gctaataccc aggcacgaca tattgctact ttctttccgg gacgcatgac
    61861 cggaactcct gcagaaatgt tatctgccga ttatattcgc caacagtttc agcaaatggg
    61921 ttatcgcagt gatattcgga catttaatag tcggtatatt tataccgcca gcgataatcg
    61981 taagagctgg cataacgtga cgggaagtac ggtgattgcc gctcatgaag gcaaagcacc
    62041 gcagcagatc atcattatgg cgcatctgga tacttacgcc ccgctgagcg atgctgacgc
    62101 cgatgccaat ctcggcgggc tgacgttaca aggaatggat gataacgccg caggtttagg
    62161 tgtcatgctg gaattggcag aacgcctgaa aaatacgcct accgagtatg gtattcgatt
    62221 tgtggcgacc agcggcgaag aggaagggaa attaggcgct gagaatttac tcaagcggat
    62281 gagtgacacc gaaaagaaaa atacgctgct ggtgattaat ctcgataact taattgttgg
    62341 cgataaattg tatttcaaca gcggtgtaaa aacccctgaa gcagtaagga aattaacgcg
    62401 cgacagggca ctggcaattg cgcgcagtca gggaatagcc gcgacgacca atcctggttt
    62461 gaataaaaac tatccgaaag gcaccgggtg ttgtaatgac gcagaaatat tcgacaaagc
    62521 gggcattgct gtactttcgg tggaagcgac taactggaat cttgggaata aggatggtta
    62581 tcagcaacgc gcaaaaacag ccgcattccc tgcgggaaat agctggcatg acgtcaggtt
    62641 tgataatcaa cagcatattg ataaggcact tcctggaaga atagaacgtc gctgccgtga
    62701 cgttatgcgg ataatgctac ctctggtgaa agagttggcg aaggcgtctt gatgggttgg
    62761 aaaatgggag ctgggagttc taccgcaggg gcgggggaac tccaagtgat atccatcatc
    62821 gcatccagtg cgcccggttt atccccgctg gcgcggggaa caccaacgaa attgagagca
    62881 aaggtcgcta cgcagcggtt tatccccgct ggcgcgggga acacttcatg aagcacgctg
    62941 gaatttatat ttgccccggt ttatccccgc tggcgcgggg aacacttcat gaagcacgct
    63001 ggaatttata tttgccccgg tttatccccg ctggcgcggg gaacacgcgc agcccgatgc
    63061 ggttagagat ataggcctcc ggtttatccc cgctggcgcg gggaacactt tacgtcgaag
    63121 cgcctttttc gcctccaggt cggtttatcc ccgctggcgc ggggaacaca aaaaatgatg
    63181 ctgtatttca ctattgggtt ccggtttatc cccgctggcg cggggaacac ccgttaaaat
    63241 attcgcccgt tgtgtaagcg tacggtttat ccccgctggc gcggggaaca catctccagc
    63301 gccttttcga cgcaacggtg cgccggttta tccccgctgg cgcggggaac actgaccgat
    63361 tttattgatc gcccgataga cctgcggttt atccccgctg gcgcggggaa cacccagatt
    63421 ccgctttctc taccttctct ttttccggtt tatccccgct ggcgcgggga acacgggttg
    63481 tgcgccctgg tgggcgaaaa cggtggcggt ttatccccgc tggcgcgggg aacacatttt
    63541 cctgatcgag ttttgagaat tttgtcgcgg tttatccccg ctggcgcggg gaacacacta
    63601 agcatacata tctgttttta aacaaattta ttccacatca acaatctacc aactaaattc
    63661 aaacatttcc ttatttttaa agaacacata acctattgat tatcaacagg aagaaaagaa
    63721 accaaacgta acccatccaa atccaccgga atacgtctgt tttctcccca ggtctgaaat
    63781 tcaaaacccg attcggtatt ggtcgcccag gccatcacca catttccgca accagccagt
    63841 tgggtaattt gttgccagat catctcccga atacgttttg atgtatcacc aacatacaca
    63901 ccggcacgca cttccagtag ccagattgcg agccgtccac gtaagcgcgg agggacattt
    63961 tctgtaacaa ccacgaccat gctcatccgc cgcgcccccg gtgaccacta tcacccagcg
    64021 tttcaggttc agggatggca ggcggtaaca tatccggcgc gggttgtggt ggttcaattt
    64081 cacctgcagc aaggacttcc tcaattaacg gtattaattt gcccgttaac ttagtgctac
    64141 ggaaaatatc gcgacaggct aatctgactt ctttatcagg ttctgcgggt tgcctcgctg
    64201 ctatttcaaa tgcctttggc acaaccgaat caaatttaat gatatcggct atgtcataaa
    64261 caaatgaaag cggtttgcca ctatgaataa atccaatagt gggcgcatat cccgcggcta
    64321 atactgccgc ttcagaaata ccgtacagac atgatgtggc agcactgatg cagcgattca
    64381 caacatcgcc tttttcccag tctttaggat cgtatttgcg accattccat ttcacaccat
    64441 attgtttcgc cagtaatgca taggtctggc gaacgcggga tccctcaatt ccccgtagct
    64501 gatccactga acggcgagct ggcggtggct cacgaaaacg taattcatac attttgcgca
    64561 ccaccttcag gcgtagatct tccgttaaag ccagctttgc ctggtagagt aatttatctg
    64621 cccgcgcccc tccgggttgt ccggaagagt aaacgcgaac gcccgcttca ccgacccaga
    64681 ccagcagtgt tcccaccgtg gcggccagat gcaccgccgc gtgggaaact ctcgttcccg
    64741 gttcgagcat aatgcaggcg accgatccca ccggaatgtg cgtgcggatc ccggttttgt
    64801 cgatcagcac gaaagcgccg tccagtacgt cgatttgacc gtactggagg aagatcatag
    64861 aggtgcgatc ttttaacggg atcggactca gtggtacaaa cgtcacgcct ctgctccggg
    64921 tttgatcagc atcagaccac agccgaacgc gcggcttttg ccatacccct gactgagacg
    64981 ttgcagaaat aacccgggat cggtgaccgt aagcatcccc gtataatcca cgctactgaa
    65041 ctggatcagt tgccgggagt tttcccgccg cagttgctgt tgtcggtagg catcaaccga
    65101 ggtatccagc agtgtaaaac cgcttctctc cccctgcgct gccagccagt ccagcgccgc
    65161 ctgttgttga tgcaaccaga catcacgccc ttccgcctgt cccctcacct gccgtttcgc
    65221 ctccatcagc agatcgtggc gcttgcccgc tttacaaatt gtgggattcg cccgcaggtt
    65281 gaaacaaagg gattgtccgg tacgcagctc cggagcaaat gaccggcatt cgatagtgaa
    65341 agtttcactt tccgccgggc gttcctgcga gaggacaaaa aagcgaaacg caccctgaag
    65401 ttcctcccga cgataaagaa attgcctttc tttgccgcca gggaagagat cccacagcca
    65461 ctgatgcatc acatattcac cgcgatccac cagatgcagc aactgcgcag gcaaaagctg
    65521 agcggtatgt aaggttattc ttgagaggta catggttcct ccttgctgag ccacggcccc
    65581 tgattgacgg tgcgttcccc aaacagccac tgctggcgat ttaaaggaac atcccggcgg
    65641 cgtaatattt tgctcacgac caggccgtcg tgctcccctt cccaccagca ttcatcctga
    65701 agtttcggga gtgagacttt caggtcgtgg aaatgatcct gatactgttg gtatgcgtta
    65761 cgtaaaacat cagacgcgtt gccttcgagc agtaacggcg caagtggtaa tgccagcgga
    65821 tgactttttc gccccagata aagaggaaaa actggatggc gtaaaccgcc ctgcaactgt
    65881 tcgaggctgt aaggcgcatc ggctgttgtt gccaccgcca ccatccacca ggcgtcggtg
    65941 tagtagtcgc gccgggagat aatcgcgctc agaagatcag ggtcgctcaa ctcttcgcga
    66001 cggctgaaat aacgcgcttt acgcacctct tttggcatct ggatcgtgtg ataatcccgt
    66061 gcccagcgcg ggttacggct ggcgcaaacc accagtgaat agtggcgatt aaacgcgttt
    66121 aagcgttcgg tatcatcacg ccgaatccct accccggcag ccagcagacc cagcaatgct
    66181 gagcgcgaag gcagttcatg ggtatgacgc acttcgccgg gggcatcgac gccccaggat
    66241 gccattggcc catgaagctg aaaaatcaga tattggctca taagccgccc cttacgcgca
    66301 gataaagtcc agcacgtcct tcatgcttcc ctgtttgttc atcacgtcaa aacttgcgca
    66361 ttcggtcttc tgttcgtaga ccgtattcat attttcgcga agcgttgtaa tacgctgcac
    66421 cgccacgtct aactgccggg tgccattaat gggttcatag aaggccgcag ccagagaacg
    66481 cggttgatcg gtgccttttt ccgccagcgc ccaggaagca taggcacggc tggcaaagct
    66541 attttgttta ccggttgggg aaactttaag cgcggcttcc gtaaaagcgc gtatggtctg
    66601 attagctaac gcttcgtcac cgccgaggtt ttctaccagc agatctttat caatgcagat
    66661 ataggtgtag aaaagtgctg aaccgaatcc ggtttctccg agatgcccgg caccggcatc
    66721 ttcagaggcc tggcgcaaat catcaacggc ggtgaaaaaa tcatcttcga caatcgtttc
    66781 actgacacca aacgcatgcg cgacctggca ggcggcttca acattaaact caggtttatt
    66841 cgccagcata cgaccaaaca tggcgatatc taccgccata cggtctttgc gtaacagact
    66901 gagatcttcc tcttttggcg cgcgcttttc ttctgccagt tgatgggcca gcgcttttac
    66961 ggcgtcaaat tctgccgggc tgatatggac taattgttca gtttcggcgt tagtgagcgg
    67021 atcttttggt tttttgtcgt ttttagcttt cccaagataa tctgcaattt ttgccgccca
    67081 ttcgatggct tttttatctt cgattccttt ctcaatcagg atagttgccg cctcacgcgc
    67141 gatacgccca ctgcgaatac caatatggcc cgccagcgcc tgttcaaaaa gtgcagaagt
    67201 gcgccacgca cgtttcagac tttgcgagga aacgcgcaga cgcgttgctc cacccaacac
    67261 cacggttttt ggcgcaccgg tgtcatcacg gttaaggttg gcagcagggt aagcggttaa
    67321 caaatgaagc tgaataaatg tcgtcatgag atagtccttt attaattttg ttcgttatcg
    67381 gcgtcaccgg cctggtaata ttccagcgcc cagcgaatac ggataaattc ggttggcctc
    67441 tgctggcggc ggtgatgatt gagcaggtcg tcgctctcct ggcaccagcg gaaaatatcg
    67501 tctgccaaag agataagatt gacggaaccg tttaataatt tgaccgcgcg acgtaactga
    67561 cgcagtaaat catccggcgt ttttactgcc gacaggcaag taaaacgccc ctctgacatt
    67621 accgccgcca gctgtgcggc aaaaggctgc cgttcatcaa tggctttaac attggcggca
    67681 acggcggcga ccagtgccag tgcggtaaaa cgccactctt gtgcttcaat tttccacaaa
    67741 gtgtgggtct gcatcagcag agaacgaaac ccttctgaca agcaaacatc attaaccgtt
    67801 gtgctacgcc gcagactggc acgattgccg cgtttagcct gcaactcttc gtgccattta
    67861 cgcagcgtgg ctttgtgccc gtcttttaca atactcattc agcagcctcc tgctttttct
    67921 ccctggcggc tttagcactt tgcttctccg ccgatgttgt aaaatatttt ttgcgcgcgg
    67981 tcatgacgcg ttttaaatca acgggctcat aaggattggt gaatacacgc tcgtcaaaat
    68041 cctgacgcgc gaataaccaa atctccttat tccatttgct gagtaatcca tccgcatcct
    68101 gaccttcttc aatttggcgc actaacctca ggaagcgatg ctgagttttg ttccagaagt
    68161 cgatatccac aaaactgaaa tcaccccgtg caccttttgg atcggagaac catgcttctt
    68221 tcaatgcact ccgtaacaga cttagaatgc gtgaagccgt ttgcgcagcc agccgcagtt
    68281 tcggtatctg gccttctttt ttattgagca gcagcgggaa acggtgttcg taccaacagc
    68341 gggctttcat gttgtcgaaa tcatagccaa atccccatag gcctactttt gcctgcttga
    68401 gactgctggc attaaagagt ttcaccacca gagcgggaag ttccgtattg ttttctgact
    68461 tacccgtttc gataaggcct aaccagtcgc gccaaattaa accgcctggt tgtggtttaa
    68521 ctgagtaaaa ctcaccaccc tctttaagtg gtacacggta aggcgttaat ggatgctgcc
    68581 acatggcata attcgcaccg taatttttgg tcgtcatcag gctcagaagc gcgtcgtcct
    68641 gctcaccgca aatatcgcag ttgccgactg tcgtggtatt aaaatcaata cgaatacgcc
    68701 gcggcattcc ccagtacgcc tggagtttat tgacctgatc atcggttacc accgcaccgg
    68761 ccagttcgct ggtacgcgtc gggccaagcc aggggaaaac cagatcgtca aattttttgg
    68821 gtagcggtaa gtcggcttca tcctgcggca tcacgttgag ccacagtttg cgccacaagg
    68881 gggcttgttg attgccctga tactcctgca attcaatcag agtcgtcatc ggcccaccgc
    68941 cgcgtatacc ggtgcgatag cctttgccac ctgacggcgc atttaactgt agggagaaca
    69001 gagctaacgc agaacaatga gagcatacgt gttcagtcac gccacgctta ataaagtggt
    69061 ctttattaaa cttcgttgtt tgagcgccgg gaatctcagg cagtagcgaa gcgacctgaa
    69121 ctttatcgcc catgagcacc tcgaaatcct gcataaatga aggtgaatct gggccaaact
    69181 ggaaagcgtg ttctaatgac agcaatgctt cccgtagctt ttcagcttcc agcccgtctt
    69241 cccagatatc atcccaacga cgataatctt ttggcgcgaa actgctttgt agtaacccca
    69301 gcaaaaactg ccatgccgcc ccctggagat ctgcccgcgg cgcagcgata tcgacaacat
    69361 tttcatccgc cagatcgact ggcgccagtt tgcctgtcgt tccgtcttta aaacgaacgg
    69421 gcaaccacgg ggttgtcaga agtgaaaacg agttcatacg catcctctcg taaaaaagac
    69481 catccctgat cggttatcca tcattccatc tttttaggtg tatcaactat tcagagagct
    69541 ctatcgcagg catctcaacc aaccttgcca atcaatccct ccgtagccga atacccacaa
    69601 ctttcgttat cggtgactaa aatcacgttt gccatctctg gatcttgccg ctgttcaatg
    69661 caccactgcc tgaacgcttc cccttccagt aaagaaaact catcgcgatg ttttttccac
    69721 cagcttcgac gcactctgac aacactcatt tcccatgcgt gagcgccagt ggtataaggc
    69781 ttcaccacac cgtcaataca ggtagccagc cacagggaaa cagattcctc agccagacgt
    69841 gtcgacagtt tttcagggag gtaatcgttg atattggcgg catagccggg cctgaagttg
    69901 agtacaaact ttttagccat tgcacgatcg cagtaatatt tgcccacttg ctcctgctcg
    69961 gagcgagcaa acccttccgg catcaccacg tcctcaccgt agactgattc aataagaagc
    70021 cgggctgagt gtggcatttg aatagcgcct tgctgacgca gtacacgctg cgtcagccag
    70081 attcgtccat gatcgggata gatatatgca ctgttccgca tggcactgcc aaaccattct
    70141 tcatcaggtg aatcgtccca gacgggggcc agaatcagca attcaggagg ggaacgctcg
    70201 tcttttccat cacgctttaa ctgaccatta atatcgcgga tatgccgctg taatcgcccc
    70261 gctcgctgga tcagcaaatc aatgggggca aggtcggaaa tcatttcgtc caggtcgcaa
    70321 tcaacgctct gctccagtac ctgagtgcta ataagggctt ttccggcacg ctgtgagcta
    70381 ccttctttac caaagcgcgc cagcgttttc gtttcgattc gctggcgatc gctaaaagca
    70441 aagcggctat gaaagagtga aaggctggaa gtgggaatga cgccgcgggc aagcagctga
    70501 cgatgaacct taatagcgtc atcgacagaa ttccggatcc aggcgatgca ttttccctga
    70561 cttaccgccg actcgatacg cgcaatactc tcttgttcac tatgaagcca acccacgctg
    70621 acgctacgct caacgtcttt gcgcgtcgct acccggtgtg agttcacatc ggatttcgtg
    70681 acatgcgtca gccaggggta atcatccttt tccaggaacg gagcttcttg ctggccctct
    70741 gtaccccgcg caaaggcagc gacgagtttg tcgcgctgct gttgagataa cgtggcagaa
    70801 agcaaaataa cgctgtttcc gccacgcgcc tgccgctcga tcaacccttc aagaatgcac
    70861 gacatgtaag cgtcacaggc gtggatctca tcagccagca ggattttgtt actcagcccc
    70921 agaagccgca gattattatg tttgaacggc atcaccgcca tcatcgcctg atccagcgtg
    70981 ccgacgccaa tttcagccag caacgccttc ttgttactgt cggcaaacca ggccgcacat
    71041 ccctgactga acgtttgttc atccggttct tctgacccga ctaaatcacc agaccagagt
    71101 gattcattaa agcggtccat taatgtgcgg gcactatgtg ccagcaccag gctggggcgg
    71161 gattctggcg aatagaaagc aagccaggtt ttgaccagcc gatcgtacat ggcattggcc
    71221 gttgccattg ttggcagacc aaaaaacagc ccctgagctt tccccgcagc tatcaacctg
    71281 tgcgccagga taagcgccgc ttctgtttta cctgcgccag tcacatcttc cagaataaat
    71341 aactgcggtc cttgctggct gatatccaga tccagcacct tttgctgtaa cggtgtcgga
    71401 ttctcaataa aaggaaacag cgtattaatt ccgttgaaag gcgcgacttt tgcttttaga
    71461 ggaaagacgg ttaaggcgtt ttgagcctga attaaagttt tctgccagta acctttaata
    71521 tccattgggt gtgcgacgcg tggaaaaaat cgcgttgacg aacccgtcca gtctgcgagc
    71581 acgacggttg cagagatata ccaggaaagg tgttttataa gttcaatgcc ctcatcatca
    71641 tcccagaatg cggggatctc tatgagcgga aacagtggtt tgatttcaag gagaaaatct
    71701 cgtgctgcag ctttgtcttc aggcagaaaa ttatccaatt catccatacg atcagggggc
    71761 tgaccatgat gccctgtcgt cacgggcatc cacatttcta tcactcgcct aagtttgcgc
    71821 ggagagagcg aagatgaagg aagtaactcc tgacattcac ttaaataatg attccacaac
    71881 cagtagccca gcgttgaatg agagattttt tcgtaatttt ttctggcacc ttcctgaatc
    71941 ttgagttcag ggggcaggta aagttgttga aaagagcggg caaattttcc aatatcgtgc
    72001 cagcacagca accaggcgaa aaattgagcc gcctgttcct tgtcagaaat ccctaattga
    72061 cgaaaataat cagccagccc gaagcaattt cttttaacca ttaaatagcc catcgcggct
    72121 acatccagcg aatgccagca aagaaggtga tagtcgtcgc ccccgtcttt ctcgccgcgt
    72181 cgggtttttc cccagaaatc aaaaaaagtc acaatatttt tatccttcag taaacttaaa
    72241 ggatatttac g
//
LOCUS       DAPGUL010000011        62429 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.011, whole genome shotgun sequence.
ACCESSION   DAPGUL010000011 DAPGUL010000000
VERSION     DAPGUL010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 62429)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62429)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62429
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.011"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(330..872)
                     /locus_tag="RHX21_000836"
     CDS             complement(330..872)
                     /locus_tag="RHX21_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDV1986064.1"
                     /translation="MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLISYSTRHPKHDMQ
                     HLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVIFNPNLFPYENMEGKI
                     DRPEEYADIATKCVTNFREKNRDRCLVILSRNDEALNSQRTSEELHHYYEIVWDEEQT
                     HKFKNISPHLQRIKAFKTLG"
     gene            complement(895..1920)
                     /gene="nagZ"
                     /locus_tag="RHX21_000837"
     CDS             complement(895..1920)
                     /gene="nagZ"
                     /locus_tag="RHX21_000837"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HDV1986065.1"
                     /translation="MGPVMLDVKGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRE
                     LVRQIRAASRNHLVVAVDQEGGRVQRFREGFTRLPAAQSFAALSGMEEGGKLAQEAGW
                     LMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPQKALAIASRFIDGMHEAGMKT
                     TGKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSSLIRENKLDAIMPAHVIYSD
                     VDPRPASGSPYWLKTVLRQELGFDGVIFSDDLSMEGAAIMGSYAERGQASLDAGCDMI
                     LVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRQELMDSARWKAISTRLNQLHERW
                     QEEKAGH"
     gene            complement(1931..2755)
                     /gene="thiK"
                     /locus_tag="RHX21_000838"
     CDS             complement(1931..2755)
                     /gene="thiK"
                     /locus_tag="RHX21_000838"
                     /EC_number="2.7.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine kinase"
                     /protein_id="HDV1986066.1"
                     /translation="MPFRSNNPIMRDELLSRFFPQFHPVTTFNSGLSGGSFLIEHQGQ
                     RFVVRQPHDPDAPQSAFLRQYRALSQLPASIAPKPHLYLRDWMVVDYLPGAVKTYLPD
                     TNELAGLLYYLHQQPRFGWRITLLPLLELYWQQSDPARRTVGWLRMLKRLRKAREPRP
                     LRLSPLHMDVHAGNLVHSASGLKLIDWEYAGDGDIALELAAVWVENTEQHRQLVNDYA
                     TRAKIYPAQLWRQVRRWFPWLLMLKAGWFEYRWRQTGDQQFIRLADDTWRQLLIKQ"
     gene            complement(2736..3377)
                     /gene="lpoB"
                     /locus_tag="RHX21_000839"
     CDS             complement(2736..3377)
                     /gene="lpoB"
                     /locus_tag="RHX21_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein activator LpoB"
                     /protein_id="HDV1986067.1"
                     /translation="MTKMSRYALITALAMFLAGCVGQREPAPVEEVKPAPEQPAEPQQ
                     PVPTVPSVPTIPQQPGPIEHEDQTAPPAPHIRHYDWNGAMQPMVSKMLGADGVTAGSV
                     LLVDSVNNRTNGSLNAAEATETLRNALANNGKFTLVSAQQLSMAKQQLGLSPQDSLGT
                     RSKAIGIARNVGAHYVLYSSASGNVNAPTLQMQLMLVQTGEIIWSGKGAVSQQ"
     gene            complement(3391..3768)
                     /locus_tag="RHX21_000840"
     CDS             complement(3391..3768)
                     /locus_tag="RHX21_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcfL family protein"
                     /protein_id="HDV1986068.1"
                     /translation="MRKGCFGLVSLALLLLVGCRSHPEIPVNDEQSLVMESSLLAAGI
                     SAEKPVLSTSDIQPSASSTLYNERQEPVTVHYRFYWYDARGLEMHPLERPRSVSIPAH
                     SAVTLYGSANFLGAHKVRLYLYL"
     gene            complement(3771..4130)
                     /gene="hinT"
                     /locus_tag="RHX21_000841"
     CDS             complement(3771..4130)
                     /gene="hinT"
                     /locus_tag="RHX21_000841"
                     /EC_number="3.9.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415621.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleoside phosphoramidase"
                     /protein_id="HDV1986069.1"
                     /translation="MAEETIFSKIIRREIPSDIVYQDDLVTAFRDISPQAPTHILIIP
                     NILIPTVNDVSAEHEQALGRMITVAAKIAEQEGIAEDGYRLIMNTNRHGGQEVYHIHM
                     HLLGGRPLGPMLAHKGL"
     gene            4464..6653
                     /gene="fhuE"
                     /locus_tag="RHX21_000842"
     CDS             4464..6653
                     /gene="fhuE"
                     /locus_tag="RHX21_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric-rhodotorulic acid/ferric-coprogen
                     receptor FhuE"
                     /protein_id="HDV1986070.1"
                     /translation="MLSTQFNRDNQYQAITKPSLLAGCIALALLPSAAFAAPATEETV
                     IVEGSATAPDDGENDYSVTSTSAGTKMQMTQRDIPQSVTIVSQQRMEDQQLQTLGEVM
                     ENTQGISKSQADSDRALYYSRGFQIDNYMVDGIPTYFESRWNLGDALSDMALFERVEV
                     VRGATGLMTGTGNPSAAINMVRKHATSREFKGDVSAEYGSWNKERYVADLQSPLTEDG
                     KIRARIVGGYQNNDSWLDRYNSEKTFFSGIVDADLGDLTTLSAGYEYQRIDVNSPTWG
                     GLPRWNTDGSSNSYDRARSTAPDWAYNDKEINKVFMTLKQRFADTWQATLNATHSEVE
                     FDSKMMYVDAYVNKADGMLVGPYSNYGPGFDYVGGTGWNSGKRKVDALDLFADGSYEL
                     FGRQHNLMFGGSYSKQNNRYFSSWANIFPDEIGSFYNFNGNFPQTDWSPQSLAQDDTT
                     HMKSLYAATRVTLADPLHLILGARYTNWRVDTLTYSMEKNHTTPYAGLVFDINDNWST
                     YASYTSIFQPQNDRDSSGKYLAPITGNNYELGLKSDWMNSRLTTTLAIFRIEQDNVAQ
                     STGTPIPGSNGETAYKAVDGTVSKGVEFELNGAITDNWQLTFGATRYIAEDNEGNAVN
                     PNLPRTTVKMFTSYRLPVMPELTVGGGVNWQNRVYTDTVTPYGTFRAEQGSYALVDLF
                     TRYQVTKNFSLQGNVNNLFDKTYDTNVEGSIVYGAPRNFSITGTYQF"
     gene            complement(6713..8146)
                     /gene="ptsG"
                     /locus_tag="RHX21_000843"
     CDS             complement(6713..8146)
                     /gene="ptsG"
                     /locus_tag="RHX21_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIBC"
                     /protein_id="HDV1986071.1"
                     /translation="MFKNAFANLQKVGKSLMLPVSVLPIAGILLGVGSANFSWLPAVV
                     SHVMAEAGGSVFANMPLIFAIGVALGFTNNDGVSALAAVVAYGIMVKTMAVVAPLVLH
                     LPAEEIASKHLADTGVLGGIISGAIAAYMFNRFYRIKLPEYLGFFAGKRFVPIISGLA
                     AIFTGVVLSFIWPPIGSAIQTFSQWAAYQNPVVAFGIYGFIERCLVPFGLHHIWNVPF
                     QMQIGEYTNAAGQVFHGDIPRYMAGDPTAGKLSGGFLFKMYGLPAAAIAIWHSAKPEN
                     RAKVGGIMISAALTSFLTGITEPIEFSFMFVAPILYIIHAILAGLAFPICILLGMRDG
                     TSFSHGLIDFIVLSGNSSKLWLFPIVGIGYAIVYYTIFRVLIKALDLKTPGREDATED
                     AKATGTSEMAPALVAAFGGKENITNLDACITRLRVSVADVSKVDQAGLKKLGAAGVVV
                     AGSGVQAIFGTKSDNLKTEMDEYIRNH"
     gene            complement(8441..9238)
                     /locus_tag="RHX21_000844"
     CDS             complement(8441..9238)
                     /locus_tag="RHX21_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDV1986072.1"
                     /translation="MFLVDSHCHLDGLDYESLHKDVDDVLAKAAARDVKFCLAVATTL
                     PGYLHMRDLVGERDNVVFSCGVHPLNQNDPYDVEDLRRLAAEEGVVALGETGLDYYYT
                     PETKVRQQESFIHHIQIGRELNKPVIVHTRDARADTLAILREEKVTDCGGVLHCFTED
                     RETAGKLLDLGFYISFSGIVTFRNAEQLRDAARYVPLDRLLVETDSPYLAPVPHRGKE
                     NQPAMVRDVAEYMAVLKGVAVEELAQVTTDNFARLFHIDASRLQSIR"
     gene            complement(9249..10253)
                     /gene="holB"
                     /locus_tag="RHX21_000845"
     CDS             complement(9249..10253)
                     /gene="holB"
                     /locus_tag="RHX21_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HDV1986073.1"
                     /translation="MRWYPWLRPDFEKLVASYQAGRGHHALLIQALPGMGDDALIYAL
                     SRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLAPEKGKNMLGIDAVREVTEKLNE
                     HARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCR
                     LHYLAPPPEQYAVTWLSREVTMSQDALLAALRLSAGSPGAALALFQGDNWQARETLCQ
                     ALAYSVPSGDWYSLLAALNHEQAPARLHWLATLLMDALKRHHGAAQVTNVDVPGLVAE
                     LANHLSPSRLQAILGDVCHIREQLMSVTGINRELLITDLLLRIEHYLQPGVVLPVPHL
                     "
     gene            complement(10250..10891)
                     /locus_tag="RHX21_000846"
     CDS             complement(10250..10891)
                     /locus_tag="RHX21_000846"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HDV1986074.1"
                     /translation="MRSKYIVIEGLEGAGKTTARNVVVETLEQLGIRDMVFTREPGGT
                     QLAEKLRSLVLDIKSVGDEVITDKAEVLMFYAARVQLVETVIKPALANGTWVIGDRHD
                     LSTQAYQGGGRGIDQHMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGELDRIE
                     QESFDFFNRTRARYLELAAQDKSIHTIDATQPLEAVMDAIRTTVTHWVKELDA"
     gene            complement(10881..11903)
                     /gene="yceG"
                     /locus_tag="RHX21_000847"
     CDS             complement(10881..11903)
                     /gene="yceG"
                     /locus_tag="RHX21_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein YceG"
                     /protein_id="HDV1986075.1"
                     /translation="MKKVLLIILLLLVVLGIAAGVGVWKVRHLADSKLLIKEETIFTL
                     KPGTGRLALGEQLYADKIINRPRVFQWLLRIEPDLSHFKAGTYRFTPQMTVREMLKLL
                     ESGKEAQFPLRLVEGMRLSDYLKQLREAPYIKHTLSDDKYATVAQALELENPEWIEGW
                     FWPDTWMYTANTTDVALLKRAHKKMVKAVDSAWEGRADGLPYKDKNQLVTMASIIEKE
                     TAVASERDQVASVFINRLRIGMRLQTDPTVIYGMGERYNGKLSRADLETPTAYNTYTI
                     TGLPPGAIATPGADSLKAAAHPAKTPYLYFVADGKGGHTFNTNLASHNKSVQDYLKVL
                     KEKNAQ"
     gene            complement(11906..12715)
                     /gene="pabC"
                     /locus_tag="RHX21_000848"
     CDS             complement(11906..12715)
                     /gene="pabC"
                     /locus_tag="RHX21_000848"
                     /EC_number="4.1.3.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate lyase"
                     /protein_id="HDV1986076.1"
                     /translation="MFLINGYKQESLAVSDRATQFGDGCFTTARVIDGKVSLLSAHIQ
                     RLQDACQRLMISCDFWPQLEQEMKTLAAEQQNGVLKVVISRGSGGRGYSTLNSGPATR
                     ILSVTAYPAHYDRLRNEGMTLALSPVRLGRNPHLAGIKHLNRLEQVLIRSHLEQTNAD
                     EALVLDSEGWVTECCAANLFWRKGNVVYTPRLDQAGVNGIMRQFCIRLLAQSSYQLVE
                     VQASLEEALQADEMVICNALMPVMPVRACGDVSFSSATLYEYLAPLCERPN"
     gene            complement(12835..14076)
                     /gene="fabF"
                     /locus_tag="RHX21_000849"
     CDS             complement(12835..14076)
                     /gene="fabF"
                     /locus_tag="RHX21_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HDV1986077.1"
                     /translation="MSKRRVVVTGLGMLSPVGNTVESTWKALLAGQSGISLIDHFDTS
                     AYATKFAGLVKDFNCEDIISRKEQRKMDAFIQYGIVAGVQAMQDSGLEITEENATRIG
                     AAIGSGIGGLGLIEENHTSLMNGGPRKISPFFVPSTIVNMVAGHLTIMYGLRGPSISI
                     ATACTSGVHNIGHAARIIAYGDADVMVAGGAEKASTPLGVGGFGAARALSTRNDNPQA
                     ASRPWDKERDGFVLGDGAGMLVLEEYEHAKKRGAKIYAELVGFGMSSDAYHMTSPPEN
                     GAGAALAMANALRDAGIEASQIGYVNAHGTSTPAGDKAEAQAVKTIFGEAASRVLVSS
                     TKSMTGHLLGAAGAVESIYSILALRDQAVPPTINLDNPDEGCDLDFVPHEARQVSGME
                     YTLCNSFGFGGTNGSLIFKKI"
     gene            complement(14164..14400)
                     /gene="acpP"
                     /locus_tag="RHX21_000850"
     CDS             complement(14164..14400)
                     /gene="acpP"
                     /locus_tag="RHX21_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDV1986078.1"
                     /translation="MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELV
                     MALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA"
     gene            complement(14611..15345)
                     /gene="fabG"
                     /locus_tag="RHX21_000851"
     CDS             complement(14611..15345)
                     /gene="fabG"
                     /locus_tag="RHX21_000851"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="HDV1986079.1"
                     /translation="MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQA
                     ISDYLGANGKGLMLNVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEE
                     WNDIIETNLSSVFRLSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIG
                     FSKSLAREVASRGITVNVVAPGFIETDMTRALSDDQRAGILAQVPAGRLGGAQEIANA
                     VAFLASDEAAYITGETLHVNGGMYMV"
     gene            complement(15358..16287)
                     /gene="fabD"
                     /locus_tag="RHX21_000852"
     CDS             complement(15358..16287)
                     /gene="fabD"
                     /locus_tag="RHX21_000852"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDV1986080.1"
                     /translation="MTQFAFVFPGQGSQTVGMLADMAASYPIVEETFAEASAALGYDL
                     WALTQQGPAEELNKTWQTQPALLTASVALYRVWQQQGGKAPAMMAGHSLGEYSALVCA
                     GVIDFADAVRLVEMRGKFMQEAVPEGTGAMAAIIGLDDASIAKACEEAAEGQVVSPVN
                     FNSPGQVVIAGHKEAVERAGAACKAAGAKRALPLPVSVPSHCALMKPAADKLAVELAK
                     ITFNAPTVPVVNNVDVKCETNGDAIRDALVRQLYNPVQWTKSVEYMAAQGVEHLYEVG
                     PGKVLTGLTKRIVDTLTASALNEPSAMAAALEL"
     gene            complement(16303..17256)
                     /gene="fabH"
                     /locus_tag="RHX21_000853"
     CDS             complement(16303..17256)
                     /gene="fabH"
                     /locus_tag="RHX21_000853"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HDV1986081.1"
                     /translation="MYTKIIGTGSYLPEQVRTNADLEKMVDTSDEWIVTRTGIRERHI
                     AAPNETVSTMGFEAATRAIEMAGIEKDQIGLIVVATTSATHAFPSAACQIQSMLGIKG
                     CPAFDVAAACAGFTYALSVADQYVKSGAVKYALVVGSDVLARTCDPTDRGTIIIFGDG
                     AGAAVLAASEEPGIISTHLHADGSYGELLTLPNADRVNPENSIHLTMAGNEVFKVAVT
                     ELAHIVDETLAANNLDRSQLDWLVPHQANLRIISATAKKLGMSMDNVVVTLDRHGNTS
                     AASVPCALDEAVRDGRIKPGQLVLLEAFGGGFTWGSALVRF"
     gene            complement(17324..18394)
                     /gene="plsX"
                     /locus_tag="RHX21_000854"
     CDS             complement(17324..18394)
                     /gene="plsX"
                     /locus_tag="RHX21_000854"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415608.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HDV1986082.1"
                     /translation="MTRLTLALDVMGGDFGPSVTVPAALQALNSNSQLTLLLVGNPDA
                     ITPLLAKADFEQRSRLQIIPAQSVIASDARPSQAIRASRGSSMRVALELVKEGRAQAC
                     VSAGNTGALMGLAKLLLKPLEGIERPALVTVLPHQQKGKTVVLDLGANVDCDSTMLVQ
                     FAIMGSVLAEEVVEIPNPRVALLNIGEEEVKGLDSIRDASAVLKTIPSINYIGYLEAN
                     ELLTGKTDVLVCDGFTGNVTLKTMEGVVRMFLSLLKSQGEGKKRSWWLLLLKRWLQKS
                     LTRRFSHLNPDQYNGACLLGLRGTVIKSHGAANQRAFAVAIEQAVQAVQRQVPQRIAA
                     RLESVYPAGFELLDGGKSGTLR"
     gene            complement(18475..18648)
                     /gene="rpmF"
                     /locus_tag="RHX21_000855"
     CDS             complement(18475..18648)
                     /gene="rpmF"
                     /locus_tag="RHX21_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDV1986083.1"
                     /translation="MAVQQNKPTRSKRGMRRSHDALTAVTSLSVDKTSGEKHLRHHIT
                     ADGYYRGRKVIAK"
     gene            complement(18700..19221)
                     /gene="yceD"
                     /locus_tag="RHX21_000856"
     CDS             complement(18700..19221)
                     /gene="yceD"
                     /locus_tag="RHX21_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA accumulation protein YceD"
                     /protein_id="HDV1986084.1"
                     /translation="MQKVKLPLTLDPVRTAQKRLDYQGIYTPDQVERVAESVVSVDSD
                     VECSMSFAIDNQRLAVLNGDAKVTVTLECQRCGKPFTHQVYTTYCFSPVRSDEQAEAL
                     PEAYEPIEVNEFGEIDLLAMVEDEIILALPVVPVHDSEHCEVSEADMVFGELPEEAQK
                     PNPFAVLASLKRK"
     gene            19420..20004
                     /gene="yceF"
                     /locus_tag="RHX21_000857"
     CDS             19420..20004
                     /gene="yceF"
                     /locus_tag="RHX21_000857"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415605.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-methyl-GTP pyrophosphatase"
                     /protein_id="HDV1986085.1"
                     /translation="MPKLILASTSPWRRALLEKLQISFECAAPEVDETPRSDESPRQL
                     VLRLAQEKAQSLASRYPDHLIIGSDQVCVLDGEITGKPLTEENARLQLRKASGNIVTF
                     YTGLALFNSANGHLQTEVEPFDVHFRHLSEAEIDNYVRKEHPLHCAGSFKSEGFGITL
                     FERLEGRDPNTLVGLPLIALCQMLRREGKNPLMG"
     gene            complement(20116..21075)
                     /gene="rluC"
                     /locus_tag="RHX21_000858"
     CDS             complement(20116..21075)
                     /gene="rluC"
                     /locus_tag="RHX21_000858"
                     /EC_number="5.4.99.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(955/2504/2580) synthase
                     RluC"
                     /protein_id="HDV1986086.1"
                     /translation="MKTETPSVKIVAITADEAGQRIDNFLRTQLKGVPKSMIYRILRK
                     GEVRVNKKRIKPEYKLEAGDEVRIPPVRVAEREEEAVSPHLQKVAALADVILYEDDHI
                     LVLNKPSGTAVHGGSGLSFGVIEGLRALRPEARFLELVHRLDRDTSGVLLVAKKRSAL
                     RSLHEQLREKGMQKDYLALVRGQWQSHVKSVQAPLLKNILQSGERIVRVSQEGKPSET
                     RFKVEERYAFATLVRCSPVTGRTHQIRVHTQYAGHPIAFDDRYGDREFDRQLTEAGTG
                     LNRLFLHAAALKFTHPGTGEVMRIEAPMDEGLKRCLQKLRNAR"
     gene            21648..24833
                     /gene="rne"
                     /locus_tag="RHX21_000859"
     CDS             21648..24833
                     /gene="rne"
                     /locus_tag="RHX21_000859"
                     /EC_number="3.1.26.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E"
                     /protein_id="HDV1986087.1"
                     /translation="MKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKG
                     KITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPANYSAHGRPNIKDVLREGQEVIV
                     QIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRTELKEALASLEL
                     PEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRAF
                     RDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYTGEIPLFSHYQIESQIE
                     SAFQREVRLPSGGSIVIDSTEALTAIDINSARATRGGDIEETAFNTNLEAADEIARQL
                     RLRDLGGLIVIDFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRL
                     SPSLGESSHHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASY
                     LLNEKRSAVNAIETRQDGVRCVIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEE
                     AMALPSEEEFAERKRPEQPALATFAMPDVPPAPTPAEPAAPVVAPAPKAAPATPATPA
                     QPGLLSRFFGALKALFSGSEETKPTEQPAPKAEAKPERQQDRRKPRQNNRRDRNERRD
                     TRSERTEGSDNREENRRNRRQAQQQTAETRESRQQAEVTEKARTTDEQQAPRRERSRR
                     RNDDKRQAQQEAKALNVEEQSVQETEQEERVRPVQPRRKQRQLNQKVRYEQSVAEEAV
                     VAPVVEETAAAEPIVQEAPAPRTELVKVPLPVVAQTAPEQQEENNADNRDNGGMPRRS
                     RRSPRHLRVSGQRRRRYRDERYPTQSPMPLTVACASPELASGKVWIRYPIVRPQDVQV
                     EEQREQEEVQVQPMVTEVPVAAAIEPVVSAPVIEEVAEVVEAPVQVAEPQPEVVETTH
                     PEVIAAAVTEQPQVITESDVAVAQEVAEHAEPVVEPQEETADIEEVAETAEVVVAEPE
                     VVTQPAAPVVAEVAAEVETVAAVEPEITVEHNHATAPMTRAPAPEYVPEAPRHSDWQR
                     PTFAFEGKGAAGGHTATHHASAAPARPQPVE"
     gene            complement(25030..25983)
                     /gene="flgL"
                     /locus_tag="RHX21_000860"
     CDS             complement(25030..25983)
                     /gene="flgL"
                     /locus_tag="RHX21_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HDV1986088.1"
                     /translation="MRFSTQMMYQQNMRGITNSQAEWMKYGEQMSTGKRVVNPSDDPI
                     AASQAVVLSQAQAQNSQYTLARTFATQKVSLEESVLSQVTTAIQNAQEKIVYASNGTL
                     SDDDRASLATDIQGLRDQLLNLANTTDGNGRYIFAGYKTETAPFSEEKGKYVGGAESI
                     KQQVDASRSMVIGHTGDKIFDSITSNAVAEPDGSASETNLFAMLDSAIAALKTPVADS
                     EADKETAAAALDKTNRGLKNSLNNVLTVRAELGTQLNELESLDSLGSDRALGQTQQMS
                     DLVDVDWNATISSYIMQQTALQASYKAFTDMQGLSLFQLNK"
     gene            complement(25995..27638)
                     /gene="flgK"
                     /locus_tag="RHX21_000861"
     CDS             complement(25995..27638)
                     /gene="flgK"
                     /locus_tag="RHX21_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HDV1986089.1"
                     /translation="MSSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQA
                     NSTLGAGGWVGNGVYVSGVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTS
                     TSSLATQMQDFFTSLQTLVSNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNI
                     AIGASVDQINNYAKQIASLNDQISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVS
                     VQDGGTYNITMANGYSLVQGSTARQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLN
                     TGSLGGILTFRSQDLDQTRNTLGQLALAFAEAFNSQHKAGFDANGDAGEDFFAIGKPA
                     VLQNTKNKGDVAIGATVTDASAVLATDYKISFDNNQWQVTRLASNTTFTVTPDANGKV
                     AFDGLELTFTGTPAVNDSFTLKPVSDAIVNMDVLITDEAKIAMASEEDAGDSDNRNGQ
                     ALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLKTSSTTQGNVVTQLSNQQQSIS
                     GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR"
     gene            complement(27704..28645)
                     /gene="flgJ"
                     /locus_tag="RHX21_000862"
     CDS             complement(27704..28645)
                     /gene="flgJ"
                     /locus_tag="RHX21_000862"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly peptidoglycan hydrolase FlgJ"
                     /protein_id="HDV1986090.1"
                     /translation="MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMF
                     VQMMLKSMRDALPKDGLFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQ
                     PLPEESTPAAPMKFPLETVVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPA
                     QLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITT
                     TEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAG
                     YATDPHYARKLTNMIQQMKSISDKVSKTYSMNIDNLF"
     gene            complement(28645..29742)
                     /gene="flgI"
                     /locus_tag="RHX21_000863"
     CDS             complement(28645..29742)
                     /gene="flgI"
                     /locus_tag="RHX21_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415598.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring protein FlgI"
                     /protein_id="HDV1986091.1"
                     /translation="MIKFLSALILLLVTTAAQAERIRDLTSVQGVRQNSLIGYGLVVG
                     LDGTGDQTTQTPFTTQTLNNMLSQLGITVPTGTNMQLKNVAAVMVTASLPPFGRQGQT
                     IDVVVSSMGNAKSLRGGTLLMTPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQL
                     NGGRITNGAVIERELPSQFGVGNTLNLQLNDEDFSMAQQIADTINRVRGYGSATALDA
                     RTIQVRVPSGNSSQVRFLADIQNMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVA
                     QGNLSVTVNRQANVSQPDTPFGGGQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRA
                     LNALGATPMDLMSILQSMQSAGCLRAKLEII"
     gene            complement(29754..30452)
                     /gene="flgH"
                     /locus_tag="RHX21_000864"
     CDS             complement(29754..30452)
                     /gene="flgH"
                     /locus_tag="RHX21_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body L-ring protein FlgH"
                     /protein_id="HDV1986092.1"
                     /translation="MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPT
                     PVANGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKT
                     NFGFDTVPRYLQGLFGNARADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGN
                     LHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQN
                     MGWLQRFFLNLSPM"
     gene            complement(30505..31287)
                     /gene="flgG"
                     /locus_tag="RHX21_000865"
     CDS             complement(30505..31287)
                     /gene="flgG"
                     /locus_tag="RHX21_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006819466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgG"
                     /protein_id="HDV1986093.1"
                     /translation="MISSLWIAKTGLDAQQTNMDVIANNLANVSTNGFKRQRAVFEDL
                     LYQTIRQPGAQSSEQTTLPSGLQIGTGVRPVATERLHSQGNLSQTNNSKDVAIKGQGF
                     FQVMLPDGSSAYTRDGSFQVDQNGQLVTAGGFQVQPAITIPANALSITIGRDGVVSVT
                     QQGQAAPVQVGQLNLTTFMNDTGLESIGENLYTETQSSGAPNESTPGLNGAGLLYQGY
                     VETSNVNVAEELVNMIQVQRAYEINSKAVSTTDQMLQKLTQL"
     gene            complement(31425..32180)
                     /gene="flgF"
                     /locus_tag="RHX21_000866"
     CDS             complement(31425..32180)
                     /gene="flgF"
                     /locus_tag="RHX21_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgF"
                     /protein_id="HDV1986094.1"
                     /translation="MDHAIYTAMGAASQTLNQQAVTASNLANASTPGFRAQLNALRAV
                     PVEGLSLPTRTLVTASTPGADMTPGKMDYTSRPLDVALQQDGWLAVQTADGSEGYTRN
                     GSIQVDPTGQLTIQGHPVIGEAGPIAVPEGAEITIAADGTISALNPGDPANTVAPVGR
                     LKLVKATGSEVQRGDDGIFRLSAETQATRGPVLQADPTLRVMSGVLEGSNVNAVAAMS
                     DMIASARRFEMQMKVISSVDDNAGRANQLLSMS"
     gene            complement(32200..33405)
                     /gene="flgE"
                     /locus_tag="RHX21_000867"
     CDS             complement(32200..33405)
                     /gene="flgE"
                     /locus_tag="RHX21_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook protein FlgE"
                     /protein_id="HDV1986095.1"
                     /translation="MAFSQAVSGLNAAATNLDVIGNNIANSATYGFKSGTASFADMFA
                     GSKVGLGVKVAGITQDFTDGTTTNTGRGLDVAISQNGFFRLVDSNGSVFYSRNGQFKL
                     DENRNLVNMQGLQLTGYPATGTPPTIQQGANPTNISIPNTLMAAKTTTTASMQINLNS
                     SDPLPTVTPFSASNADSYNKKGSVTVFDSQGNAHDMSVYFVKTGDNNWQVYTQDSSDP
                     TGTAEPAMKLVFNANGVLTSNPTENITTGAINGADPATFSLSFLNSMQQNTGANNIVA
                     TTQNGYKPGDLVSYQINDDGTVVGNYSNEQTQLLGQIVLANFANNEGLASEGDNVWSA
                     TQSSGVALLGTAGTGNFGTLTNGALEASNVDLSKELVNMIVAQRNYQSNAQTIKTQDQ
                     ILNTLVNLR"
     gene            complement(33430..34125)
                     /gene="flgD"
                     /locus_tag="RHX21_000868"
     CDS             complement(33430..34125)
                     /gene="flgD"
                     /locus_tag="RHX21_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook assembly protein FlgD"
                     /protein_id="HDV1986096.1"
                     /translation="MSIAVTTTDPTNTGVSTTSSSSLTGSNAADLQSSFLTLLVAQLK
                     NQDPTNPMENNELTSQLAQISTVSGIEKLNTTLGSISGQIDNSQSLQASNLIGHGVMI
                     PGTTVLAGTGSEEGAVTTTTPFGVELQQAADKVTATITDKNGAVVRTIDIGELTAGVH
                     SFTWDGTLTDGSTAPNGSYNVAISASNGGTQLVAQPLQFALVQGVIRGNSGNTLDLGT
                     YGTTTLDEVRQII"
     gene            complement(34137..34541)
                     /gene="flgC"
                     /locus_tag="RHX21_000869"
     CDS             complement(34137..34541)
                     /gene="flgC"
                     /locus_tag="RHX21_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HDV1986097.1"
                     /translation="MALLNIFDIAGSALTAQSQRLNVAASNLANADSVTGPDGQPYRA
                     KQVVFQVNAAPGAATGGVKVADVIESQAPDKLVYEPGNPLADAKGYVKMPNVDVVGEM
                     VNTMSASRSYQANVEVLNTVKSMMLKTLTLGQ"
     gene            complement(34545..34961)
                     /gene="flgB"
                     /locus_tag="RHX21_000870"
     CDS             complement(34545..34961)
                     /gene="flgB"
                     /locus_tag="RHX21_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HDV1986098.1"
                     /translation="MLDKLDAALRFQQEALNLRAQRQEVLAANIANADTPGYQARDID
                     FASELKKVMQRGRDATSVVALTMTSTQHIPAQALTPPTAELQYRIPDQPSLDGNTVDM
                     DRERTQFADNSLQYQMSLSALSGQIKGMMNVLQSGN"
     gene            35116..35775
                     /gene="flgA"
                     /locus_tag="RHX21_000871"
     CDS             35116..35775
                     /gene="flgA"
                     /locus_tag="RHX21_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring formation protein
                     FlgA"
                     /protein_id="HDV1986099.1"
                     /translation="MLTIKRSVAIIAILFSPLSTASNLTSQLHNFFSAQLAGVSDEVR
                     VSIRTAPNLLPPCEQPLLSMSNNSRLWGNVNVLARCGNDKRYLQVNVQATGNYVVAAM
                     PIARGGKLEAGNVKLKRGRLDTLPPRTVLDINQLVDAISLRDLSPDQPIQLTQFRQAW
                     RVKAGQRVNVIASGDGFSANAEGQALNNAAVAQNARVRMVSGQVVSGVVDADGNILIN
                     L"
     gene            35851..36144
                     /gene="flgM"
                     /locus_tag="RHX21_000872"
     CDS             35851..36144
                     /gene="flgM"
                     /locus_tag="RHX21_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma-28 factor FlgM"
                     /protein_id="HDV1986100.1"
                     /translation="MSIDRTSPLKPVSTVQPRETTDAPVTNTRAAKTTASTSTSVTLS
                     DAQAKLMQPGSSDINLERVEALKLAIRNGELKMDTGKIADALINEAQQDLQSN"
     gene            36149..36565
                     /gene="flgN"
                     /locus_tag="RHX21_000873"
     CDS             36149..36565
                     /gene="flgN"
                     /locus_tag="RHX21_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis chaperone FlgN"
                     /protein_id="HDV1986101.1"
                     /translation="MTRLAEILDQMSAVLNDLKTVMDQEQQHLSMGQINGSQLQWITE
                     QKSSLLATLDYLEQLRKKEPNTANSVDISQRWQEITVKTQQLRQMNQHNGWLLEGQIE
                     RNQQALEMLKPHQEPTLYGANGQTSTTHRGGKKISI"
     gene            complement(36605..38140)
                     /gene="murJ"
                     /locus_tag="RHX21_000874"
     CDS             complement(36605..38140)
                     /gene="murJ"
                     /locus_tag="RHX21_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706990.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HDV1986102.1"
                     /translation="MNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVA
                     FKLPNLLRRIFAEGAFSQAFVPILAEYKSKQGEDATRVFVSYVSGLLTLALAVVTVAG
                     MLAAPWVIMVTAPGFADTADKFALTSQLLKITFPYILLISLASLVGAILNTWNRFSIP
                     AFAPTLLNISMIGFALFAAPYFNPPVLALAWAVTVGGILQLVYQLPHLKKIGMLVLPR
                     INFHDAGAMRVVKQMGPAILGVSVSQISLIINTIFASFLASGSVSWMYYADRLMEFPS
                     GVLGVALGTILLPSLSKSFASGNHDEYNRLMDWGLRLCFLLALPSAVALGILSGPLTV
                     SLFQYGKFTAFDALMTQRALIAYSVGLIGLIVVKVLAPGFYSRQDIKTPVKIAIVTLI
                     LTQLMNLAFIGPLKHAGLSLSIGLAACLNASLLYWQLRKQKIFTPQPGWMAFLLRLVV
                     AVLVMSGVLLGMLHIMPEWSLGTMPWRLLRLMAVVLAGIAAYFAALAVLGFKVKEFAR
                     RTV"
     gene            complement(38250..39173)
                     /locus_tag="RHX21_000875"
     CDS             complement(38250..39173)
                     /locus_tag="RHX21_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDV1986103.1"
                     /translation="MKKLRIGVVGLGGIAQKAWLPVLAAASDWMLQGAWSPTRAKALP
                     ICESWRIPYADSLSSLAASCDAVFVHSSTASHFDVVSTLLNAGVHVCVDKPLAENLRD
                     AERLVELAARKKLTLMVGFNRRFAPLYGELKTQLATAASLRMDKHRSNSVGPHDLYFT
                     LLDDYLHVVDTALWLSGGKASLDGGTLLTNDAGEMLFAEHHFSAGPLQITTCMHRRAG
                     SQRETVQAVTDGALIDITDMREWREERGQGVVHKPIPGWQSTLEQRGFVGCARHFIEC
                     VQNQTVPQTAGEQAVLAQRIVDKIWRDAMSE"
     gene            complement(39175..39822)
                     /locus_tag="RHX21_000876"
     CDS             complement(39175..39822)
                     /locus_tag="RHX21_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceH family protein"
                     /protein_id="HDV1986104.1"
                     /translation="MKYQLTALEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNR
                     EPVMNLSESEVQEQLDNLVKRHYLRTVSGFGNRVTKYEQRFCNSEFGDLKLSAAEVAL
                     ITTLLLRGAQTPGELRSRAARMYEFSDMAEVESTLEQLANREDGPFVVRLAREPGKRE
                     SRYMHLFSGEVEDQPAVTDMSNAVDGDLQARVEALEIEVAELKQRLDSLLAHLGD"
     gene            complement(39833..40417)
                     /gene="rimJ"
                     /locus_tag="RHX21_000877"
     CDS             complement(39833..40417)
                     /gene="rimJ"
                     /locus_tag="RHX21_000877"
                     /EC_number="2.3.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S5-alanine
                     N-acetyltransferase"
                     /protein_id="HDV1986105.1"
                     /translation="MFGYRSNVPKVRLTTDRLVVRLVHDRDAWRLADYYAENRHFLKP
                     WEPVRDESHCYPSGWQARLGMINEFHKQGSAFYFGLFDPDEKEIIGVANFSNVVRGSF
                     HACYLGYSIGQKWQGKGLMFEALTAAIRYMQRTQHIHRIMANYMPHNKRSGDLLARLG
                     FEKEGYAKDYLLIDGQWRDHVLTALTTPDWTPGR"
     gene            40653..41861
                     /gene="mdtH"
                     /locus_tag="RHX21_000878"
     CDS             40653..41861
                     /gene="mdtH"
                     /locus_tag="RHX21_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415583.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtH"
                     /protein_id="HDV1986106.1"
                     /translation="MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWA
                     AVMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLL
                     WFSCLLSGLGGTLFDPPRSALVVKLIRPQQRGRFFSLLMMQDSAGAVIGALLGSWLLQ
                     YDFRLVCATGAVLFVLCAAFNAWLLPAWKLSTVRTPVREGMTRVMRDKRFVTYVLTLA
                     GYYMLAVQVMLMLPIMVNDVAGAPSAVKWMYAIEACLSLTLLYPIARWSEKHFRLEHR
                     LMAGLLIMSLSMMPVGMVSGLQQLFTLICLFYIGSIIAEPARETLSASLADARARGSY
                     MGFSRLGLAIGGAIGYIGGGWLFDLGKSAHQPELPWMMLGIIGIFTFLALGWQFSQKR
                     AARRLLERDA"
     gene            41925..42572
                     /gene="grxB"
                     /locus_tag="RHX21_000879"
     CDS             41925..42572
                     /gene="grxB"
                     /locus_tag="RHX21_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 2"
                     /protein_id="HDV1986107.1"
                     /translation="MKLYIYDHCPYCLKARMIFGLKNIPVELHVLLNDDAETPTRMVG
                     QKQVPILQKDDSRYMPESMDIVHYVDKLDGKPLLTGKRSPAIEEWLRKVNGYANKLLL
                     PRFAKSAFDEFSTPAARKYFVDKKEASAGNFADLLAHSDGLIKNISDDLRALDKLIVK
                     PNAVNGELSEDDIQLFPLLRNLTLVAGINWPSRVADYRDNMAKQTQINLLSSMAI"
     gene            42706..43266
                     /locus_tag="RHX21_000880"
     CDS             42706..43266
                     /locus_tag="RHX21_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDV1986108.1"
                     /translation="MNKFLFAAALIVSGLLVGCNQLTQYTITEQEINQSLAKHNNFSK
                     DIGLPGVADAHIVLTNLTSQIGREEPNKVTLTGDANLDMNSLFGSQKATMKLKLKALP
                     VFDKEKGAIFLKEMEVVDATVQPEKMQTVMQTLLPYLNQALRNYFNQQPAYVLREDGS
                     QGEAMAKKLAKGIEVKPGEIVIPFTD"
     gene            43372..44418
                     /gene="pyrC"
                     /locus_tag="RHX21_000881"
     CDS             43372..44418
                     /gene="pyrC"
                     /locus_tag="RHX21_000881"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HDV1986109.1"
                     /translation="MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMP
                     NLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAA
                     KLYPANATTNSSHGVTSIDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIES
                     VMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRP
                     HLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTAL
                     GSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLV
                     PFLAGETVRWSVKQ"
     gene            44492..44737
                     /gene="dinI"
                     /locus_tag="RHX21_000882"
     CDS             44492..44737
                     /gene="dinI"
                     /locus_tag="RHX21_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein I"
                     /protein_id="HDV1986110.1"
                     /translation="MRIEVTIAKTSPLPAGAIDALAGELSRRIQYAFPDNEGHVSVRY
                     AAANNLSVIGATKEDKQRISEILQETWESADDWFVSE"
     gene            45027..45281
                     /gene="bssS"
                     /locus_tag="RHX21_000883"
     CDS             45027..45281
                     /gene="bssS"
                     /locus_tag="RHX21_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309465.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator BssS"
                     /protein_id="HDV1986111.1"
                     /translation="MEKNNEVIQTHPLVGWDISTVDSYDALMLRLHYQTPNKSEQEGT
                     EVGQTLWLTTDVARQFISILEAGIAKIESGDFPVNEYRRH"
     gene            45396..46514
                     /gene="solA"
                     /locus_tag="RHX21_000884"
     CDS             45396..46514
                     /gene="solA"
                     /locus_tag="RHX21_000884"
                     /EC_number="1.5.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-methyl-L-tryptophan oxidase"
                     /protein_id="HDV1986112.1"
                     /translation="MKYDLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPPHQHGSHH
                     GDTRLIRHAYGEGEKYVPLVLRAQTLWDELSRHNEDDPIFVRSGVINLGPADSAFLAN
                     VAHSAEQWQLNVEKLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAK
                     EAGCAQLFNCPVTAIRHDDDGVTIETVDGEYQAKKAIVCAGTWVKDLLPELPVQPVRK
                     VFAWYQADGRYSVKNKFPAFTGELPNGDQYYGFPAENDALKIGKHNGGQVIHSADERV
                     PFAEVVSDGSEAFPFLRNVLPGIGCCLYGAACTYDNSPDEDFIIDTLPDHDNTLFITG
                     LSGHGFKFASVLGEIAADFAQDKKSDFDLTPFRLSRFQ"
     gene            46562..46675
                     /locus_tag="RHX21_000885"
     CDS             46562..46675
                     /locus_tag="RHX21_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706980.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceO family protein"
                     /protein_id="HDV1986113.1"
                     /translation="MRRLLHYLINNIREHLMLYLFLWGLLAIMDLIYVFYF"
     gene            46936..47502
                     /locus_tag="RHX21_000886"
     CDS             46936..47502
                     /locus_tag="RHX21_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b"
                     /protein_id="HDV1986114.1"
                     /translation="MSFTNTPERYGVISAAFHWLSAIIVYGMFALGLWMVTLSYYDGW
                     YHKAPELHKSIGILLMMGLVIRVLWRVISPPPGPLPSYSPMTRLAAKAGHLALYLLLF
                     AIGISGYLISTADGKPISVFGWFDVPATLADAGAQADFAGALHFWLAWSVVVLSVMHG
                     FMALKHHFIDKDDTLKRMLGKSSSDYGV"
     gene            47506..48081
                     /locus_tag="RHX21_000887"
     CDS             47506..48081
                     /locus_tag="RHX21_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceI family protein"
                     /protein_id="HDV1986115.1"
                     /translation="MKKSLLGLTFASLMFSAGSAVAADYKIDKEGQHAFVNFRIQHLG
                     YSWLYGTFKDFDGTFTFDEKNPAADKVNVTINTTSVDTNHAERDKHLRSADFLNTAKY
                     PQATFTSTSVKKDGDELDITGDLTLNGVTKPVTLEAKLIGQGDDPWGGKRAGFEAEGK
                     IKLKDFNIKTDLGPASQEVDLIISVEGVQQK"
     gene            complement(48123..49175)
                     /locus_tag="RHX21_000888"
     CDS             complement(48123..49175)
                     /locus_tag="RHX21_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706977.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HDV1986116.1"
                     /translation="MPVLHNRISNDALKAKMLAESEPRTTISFYKYFHIADPKATRDA
                     LYQLFTALNVFGRVYLAHEGINAQISVPASNVETFRAQLYAFDPALEGLRLNIALDDD
                     GKSFWVLRMKVRDRIVADGIDDPHFDASNVGEYLQAAEVNAMLDDPDALFIDMRNHYE
                     YEVGHFENALEIPADTFREQLPKAVEMMQAHKDKKIVMYCTGGIRCEKASAWMKHNGF
                     NKVWHIEGGIIEYARKAREQGLPVRFIGKNFVFDERMGERISDEIIAHCHQCGAPCDS
                     HTNCKNDGCHLLFIQCPVCAEKYKGCCSEICCEESALPPEEQRRRRAGRENGNKIFNK
                     SRGRLNTTLGIPDPTE"
     gene            49400..50320
                     /gene="lpxL"
                     /locus_tag="RHX21_000889"
     CDS             49400..50320
                     /gene="lpxL"
                     /locus_tag="RHX21_000889"
                     /EC_number="2.3.1.241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid IV(A) lauroyltransferase"
                     /protein_id="HDV1986117.1"
                     /translation="MTNLPKFSTALLHPRYWLTWLGIGVLWLVVQLPYPVIYRLGCGL
                     GKLALRFMKRRAKIVHRNLELCFPEMSEQERRKMVVKNFESVGMGLMETGMAWFWPDR
                     RIARWTEVIGMEHIRDVQAQKRGILLVGIHFLTLELGARQFGMQEPGIGVYRPNDNPL
                     IDWLQTWGRLRSNKSMLDRKDLKGMIKALKKGEVVWYAPDHDYGPRSSVFVPLFAVEQ
                     AATTTGTWMLARMSGACLVPFVPRRKPDGKGYQLIMLPPECSPPLDDAETTAAWMNKV
                     VEKCIMMAPEQYMWLHRRFKTRPEGVPSRY"
     gene            50492..51718
                     /gene="mdtG"
                     /locus_tag="RHX21_000890"
     CDS             50492..51718
                     /gene="mdtG"
                     /locus_tag="RHX21_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtG"
                     /protein_id="HDV1986118.1"
                     /translation="MSPCENDTPINWKRNLIVAWLGCFLTGAAFSLVMPFLPLYVEQL
                     GVTGHSALNMWSGIVFSITFLFSAIASPFWGGLADRKGRKLMLLRSALGMGIVMVLMG
                     LAQNIWQFLILRALLGLLGGFVPNANALIATQVPRNKSGWALGTLSTGGVSGALLGPM
                     AGGLLADSYGLRPVFFITASVLILCFFVTLFCIREKFQPVSKKEMLHMREVVTSLKNP
                     KLVLSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNVAFISGMIASVPGVAALLSAP
                     RLGKLGDRIGPEKILITALIFSVLLLIPMSYVQTPLQLGILRFLLGAADGALLPAVQT
                     LLVYNSSNQIAGRIFSYNQSFRDIGNVTGPLMGAAISANYGFRAVFLVTAGVVLFNAV
                     YSWNSLRRRRIPQVSN"
     gene            51801..52175
                     /locus_tag="RHX21_000891"
     CDS             51801..52175
                     /locus_tag="RHX21_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309456.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acidic protein MsyB"
                     /protein_id="HDV1986119.1"
                     /translation="MTMYATLEEAIDAAREEFLADNPGIDAEDANVQQFNAQKYVLQD
                     GDIMWQVEFFADEGEEGECLPMLSGEAAQSVFDGDYDEIEIRQEWQEENTLHEWDEGE
                     FQLEPPLDTEEGRAAADEWDER"
     gene            complement(52176..52403)
                     /locus_tag="RHX21_000892"
     CDS             complement(52176..52403)
                     /locus_tag="RHX21_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceK/YidQ family lipoprotein"
                     /protein_id="HDV1986120.1"
                     /translation="MRLIVVSIMVTLLSGCGSIISRTIPGQGHGNQYYPGVQWDVRDS
                     AWRYVTILDLPFSLVFDTLLLPIDTHHGPYE"
     gene            complement(52576..55119)
                     /gene="mdoH"
                     /locus_tag="RHX21_000893"
     CDS             complement(52576..55119)
                     /gene="mdoH"
                     /locus_tag="RHX21_000893"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis glucosyltransferase MdoH"
                     /protein_id="HDV1986121.1"
                     /translation="MNKTTEYIDAMPIAASEKAALPKTDIRAVHQALDAEHRTWARED
                     DSPQGSVKARLEQAWPDSLADGQLIKDDEGRDQLKAMPEAKRSSMFPDPWRTNPVGRF
                     WDRLRGRDVTPRYLARLTKEEQESEQKWRTVGTIRRYILLILTLAQTVVATWYMKTIL
                     PYQGWALINPMDMVGQDLWVSFMQLLPYMLQTGILILFAVLFCWVSAGFWTALMGFLQ
                     LLIGRDKYSISASTVGDEPLNPEHRTALIMPICNEDVNRVFAGLRATWESVKATGNAK
                     HFDVYILSDSYNPDICVAEQKAWMELIAEVGGEGQIFYRRRRRRVKRKSGNIDDFCRR
                     WGSQYSYMVVLDADSVMTGDCLCGLVRLMEANPNAGIIQSSPKASGMDTLYARCQQFA
                     TRVYGPLFTAGLHFWQLGESHYWGHNAIIRVKPFIEHCALAPLPGEGSFAGSILSHDF
                     VEAALMRRAGWGVWIAYDLPGSYEELPPNLLDELKRDRRWCHGNLMNFRLFLVKGMHP
                     VHRAVFLTGVMSYLSAPLWFMFLALSTALQVVHALTEPQYFLQPRQLFPVWPQWRPEL
                     AIALFASTMVLLFLPKLLSILLIWCKGTKEYGGFWRVTLSLLLEVLFSVLLAPVRMLF
                     HTVFVVSAFLGWEVVWNSPQRDDDSTSWGEAFKRHGSQLLLGLVWAVGMAWLDLRFLF
                     WLAPIVFSLILSPFVSVISSRATVGLRTKRWKLFLIPEEYSPPQVLVDTDRFLEMNRQ
                     RSLDDGFMHAVFNPSFNALATAMATARHRASKVLEIARDRHVEQALNETPEKLNRDRR
                     LVLLSDPVTMARLHFRVWNSPERYSSWVSYYEGIKLNPLALRKPDAASQ"
     gene            complement(55112..56647)
                     /gene="mdoG"
                     /locus_tag="RHX21_000894"
     CDS             complement(55112..56647)
                     /gene="mdoG"
                     /locus_tag="RHX21_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis protein MdoG"
                     /protein_id="HDV1986122.1"
                     /translation="MMKMRWLSAAVMLTLYTSSSWAFSIDDVAKQAQSLAGKGYEAPK
                     SNLPSVFRDMKYADYQQIQFNHDKAYWNNLKTPFKLEFYHQGMYFDTPVKINEVTATA
                     VKRIKYSPDYFTFGDVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGASYFRVI
                     GAGQVYGLSARGLAIDTALPSGEEFPRFKEFWIERPKPTDKRLTIYALLDSPRATGAY
                     KFVVMPGRDTVVDVQSKIYLRDKVGKLGVAPLTSMFLFGPNQPSPANNYRPELHDSNG
                     LSIHAGNGEWIWRPLNNPKHLAVSSFSMENPQGFGLLQRGRDFSRFEDLDDRYDLRPS
                     AWVTPKGEWGKGSVELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTITFSRDED
                     KLHAPDNAWVQQTRRSTGDVKQSNLIRQPDGTIAFVVDFTGAEMKKLPEDTPVTAQTS
                     IGDNGEIVESTVRYNPVTKGWRLVMRVKVKDAKKTTEMRAALVNADQTLSETWSYQLP
                     ANE"
     gene            57041..58198
                     /gene="mdoC"
                     /locus_tag="RHX21_000895"
     CDS             57041..58198
                     /gene="mdoC"
                     /locus_tag="RHX21_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706958.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis protein MdoC"
                     /protein_id="HDV1986123.1"
                     /translation="MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAEP
                     SLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPLKKWWKVRVERVGIPMLTAIPLL
                     TLPQFIMLQYVKGKAESWPGLSLYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRI
                     RNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGMFNFIVMQTL
                     FYLPFFILGALAFIFPHLKALFTTPSRGCTLAAALAFVAYLLNQRYGSGDAWMYETES
                     VITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHI
                     TSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR"
     gene            complement(58206..59687)
                     /gene="clsC"
                     /locus_tag="RHX21_000896"
     CDS             complement(58206..59687)
                     /gene="clsC"
                     /locus_tag="RHX21_000896"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706957.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase ClsC"
                     /protein_id="HDV1986124.1"
                     /translation="MMKKTPTSTKDSLPNKEMNDLPRLASAVLPLCSQHPGQCGLFPL
                     EKSLDAFAARYRLAEMAEHTLDVQYYIWQDDMSGRLLFSALLAAAKRGVRVRLLLDDN
                     NTPGLDDILRLLDSHPRIEVRLFNPFSFRLLRPLGYITDFSRLNRRMHNKSFTVDGVV
                     TLVGGRNIGDAYFGAGEEPLFSDLDVMAIGPVVEDVADDFARYWYCKSVSPLQQVLDV
                     PEGEMADRIELPASWHNDVMTHRYLRKMESSPFINHLVDGTLPLIWAKTRLLSDDPAK
                     GEGKAKRHSLLPQRLFDIMGSPSERIDIISSYFVPTRAGVAQLLRMVRKGVKIAILTN
                     SLAANDVAVVHAGYARWRKKLLRYGVELYELKPTREQSSTLHDRGITGNSGASLHAKT
                     FSIDGKTVFIGSFNFDPRSTLLNTEMGFVIESETLAQLIDKRFIQSQYDAAWQLRLDR
                     WGRINWVDRHAKKEIILKKEPATSFWKRVMVRLASILPVEWLL"
     gene            complement(59629..60162)
                     /gene="ymdB"
                     /locus_tag="RHX21_000897"
     CDS             complement(59629..60162)
                     /gene="ymdB"
                     /locus_tag="RHX21_000897"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyl-ADP-ribose deacetylase"
                     /protein_id="HDV1986125.1"
                     /translation="MKTRIHVVQGDITKLAVDVIVNAANPSLMGGGGVDGAIHRSAGP
                     ALLDACLKVRQQQGDCPTGHAVITLAGALPAKAVVHTVGPVWRGGEQNEDQLLQDAYL
                     NSLRLVAANSYTSVAFPAISTGVYGYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYD
                     EENAHLYERLLTQQGDE"
     gene            complement(60257..60567)
                     /locus_tag="RHX21_000898"
                     /pseudo
     CDS             complement(60257..60567)
                     /locus_tag="RHX21_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309449.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
     gene            complement(60688..61020)
                     /gene="csgC"
                     /locus_tag="RHX21_000899"
     CDS             complement(60688..61020)
                     /gene="csgC"
                     /locus_tag="RHX21_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli assembly protein CsgC"
                     /protein_id="HDV1986126.1"
                     /translation="MNALLLLAALSSQITFNTTQQGDVYTIIPEVTLTQSCLCRVQIL
                     SLREGSSGQSQTKQEKTLSLPANQPIALTKLSLNISPEDRVKIVVTVSDGQSLHLSQQ
                     WPPSSEKS"
     gene            complement(61079..61534)
                     /gene="csgA"
                     /locus_tag="RHX21_000900"
     CDS             complement(61079..61534)
                     /gene="csgA"
                     /locus_tag="RHX21_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curlin major subunit CsgA"
                     /protein_id="HDV1986127.1"
                     /translation="MKLLKVAAIAAIVFSGSALAGVVPQYGGGGNHGGGGNNSGPNSE
                     LNIYQYGGGNSALALQTDARNSDLTITQHGGGNGADVGQGSDDSSIDLTQRGFGNSAT
                     LDQWNGKNSEMTVKQFGGGNGAAVDQTASNSSVNVTQVGFGNNATAHQY"
     gene            complement(61575..62030)
                     /gene="csgB"
                     /locus_tag="RHX21_000901"
     CDS             complement(61575..62030)
                     /gene="csgB"
                     /locus_tag="RHX21_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curlin minor subunit CsgB"
                     /protein_id="HDV1986128.1"
                     /translation="MKNKLLFMMLTILGAPGIAAAAGYDLANSEYNFAVNELSKSSFN
                     QAAIIGQAGTNNSAQLRQGGSKLLAVVAQEGSSNRAKIDQTGDYNLAYIDQAGSANDA
                     SISQGAYGNTAMIIQKGSGNKANITQYGTQKTAIVVQRQSQMAIRVTQR"
BASE COUNT        15257 a        16579 c        15328 g        15265 t
ORIGIN      
        1 aatgaaaatg ttcttcgcta ttgagaataa catgaatggt gcattggtca taccaaaatt
       61 gatgttaatc aagttttgtt gctgaaaaga taggcgactt taccgggtga gatcaaaaaa
      121 tagagtttat tgtttattat ttgagcaaat tcggaagagt aatatagggt gaagcgtata
      181 tcgagggcgt ttggtcgtcc tgataagatg cgcagcatcg catcaggcat tgatgctcga
      241 ctgtcggatg cggcgtggac gccttatccg acttacagaa ttcggagcgc atcaggtacc
      301 ggtaaggtta cctgatgcga cgagggcatt tacccgaggg ttttgaacgc tttaatgcgc
      361 tgtaaatgcg gggagatatt cttgaatttg tgcgtctgct cttcgtccca gacaatctcg
      421 taataatgat gcaactcttc agatgtccgc tggctgttaa gtgcttcatc attacgcgac
      481 aaaataacca gacaacgatc gcgattcttc tcgcggaagt tggtcacaca cttagtggca
      541 atatcggcat actcttccgg gcgatcaatc ttgccttcca tgttctcata agggaacaaa
      601 ttagggttga agatcacctg gcggatatcg caaagaaaac caatccgttc cgcccagtat
      661 ccgcccaggc caacgccgca aattagcgga cgctcgtcaa cgttcagttg caacattttg
      721 tccacttctt taagcagatg ctgcatatca tgtttcggat gccgcgtact gtagcttatc
      781 aagcgtacat ccgggtcaat aaactgcaat tgtaagactt tctcgtggtt acccggactg
      841 ttagagtcaa aaccgtgtaa atagataatc atcgcttcct cacataagcc agggttagtg
      901 acctgctttc tcttcctgcc agcgttcgtg taactgattc agacgggtgc tgatcgcttt
      961 ccagcgagcc gagtccatca gttcctgtcg cgaaaatgaa cctttatgat acaaacgtgt
     1021 aacacgttct gccttgatcg gtgacagatt atctaacacg ctgacggccc ctttacgatt
     1081 attgcagacc aggatcatat cgcaacccgc atccagtgat gcctgcccgc gttcggcata
     1141 actgcccata atcgcggcac cttccatcga taaatcgtca gagaaaatca cgccgtcaaa
     1201 acccagttcc tgacgcaaaa cggttttcag ccagtaggga gaaccgctcg ccggacgcgg
     1261 atcaacatca ctgtagatca catgcgcagg cataatggcg tcgagtttat tttcgcggat
     1321 taaggaactg aagaccgaca tatctttagc gcgaatctcc gcttgtggac gtggatcgca
     1381 cggtgtttct ttgtgtgagt ctgccgttac tgcaccgtgt cctgggaagt gtttcccggt
     1441 cgttttcatt ccggcttcat gcataccatc aataaaccgg ctggcaattg ccagggcttt
     1501 ttgtggatcg gcatgataag aacgctcgcc aatcgccgcg ctgatatgcc cgacatccag
     1561 cactggcgca aagctgatat caatatccat agcgatcatt tcgctggcca tcagccaacc
     1621 cgcctcttgc gccagtttgc cgccctcttc cattcctgac agcgcagcga atgattgcgc
     1681 cgctggcaag cgggtaaaac cttcacgaaa acgctgcacg cgtccacctt cctgatctac
     1741 cgccaccacc agatgattgc gcgaagctgc gcggatctgg cgcaccagtt cacgtaactg
     1801 ggcaggatca tgatagttac gcgtaaagag aatcagccct cccaccagcg gatgcgcaag
     1861 tatttcacgc tcttccgcgt ccagttcgta acctttgaca tccaacatta ctggacccac
     1921 actgctctcc ttattgtttt attaatagct gccgccaggt gtcatcggcc agcctgataa
     1981 attgttgatc gccggtttgt cgccagcggt actcaaacca ccctgctttg agcatcagca
     2041 gccagggaaa ccatcgcctg acctgacgcc ataattgcgc cggataaatc ttcgcgcgag
     2101 tggcatagtc attgaccaat tgccggtgct gttcagtatt ttccacccac accgccgcca
     2161 gttccagcgc gatatcacca tctccggcat actcccagtc gatgagtttt aaccctgacg
     2221 cgctatgcac taaatttccg gcgtggacat ccatatgcaa tggacttaag cgtaaaggcc
     2281 gtggttcccg cgctttgcgc agacgtttta acattcgcag ccaacccact gtccgccgcg
     2341 ccggatcgct ttgctgccag tacagttcca gtaacggcaa cagcgttatt cgccagccaa
     2401 aacgtggttg ttgatgtaga taatacagca agcctgccag ttcgttggta tccggcaaat
     2461 acgtttttac cgcgccgggc agatagtcga ctaccatcca gtcacggaga tataaatgcg
     2521 gcttcggtgc aatgcttgcg ggtagttgtg ataaagcccg atactggcgc aagaacgcgg
     2581 actgcggcgc atcaggatcg tgcggctgac gcacaacaaa acgctggccc tgatgttcaa
     2641 tgagaaaact cccgccacta agcccactat taaacgtcgt gacgggatga aactgcggga
     2701 aaaagcgcga cagcaattcg tcgcgcatga tgggattatt gctgcgaaac ggcaccttta
     2761 cctgaccaga taatttcgcc cgtctgcacc agcatcagct gcatttgtag ggtcggagcg
     2821 ttaacgttgc cagaggcgct ggagtacagc acgtaatgag cgccgacatt gcgggcaatg
     2881 cctatggctt tactacgggt acctaaactg tcctgcggcg acaaacctaa ctgttgctta
     2941 gccatcgaca gctgctgggc ggaaaccagt gtaaatttcc cgttattagc cagcgcattt
     3001 cgcagcgttt cggtcgcttc tgcggcattc agcgaaccgt tagtacggtt gttaacgcta
     3061 tcaaccagca ggacgctacc cgcagtcacc ccgtcagccc caagcatctt actgaccatc
     3121 ggctgcattg cgccattcca gtcataatgg cgaatatgcg gcgcaggcgg tgccgtttga
     3181 tcttcgtgct caattgggcc tggctgctgc gggatcgtcg gcaccgaggg cactgtgggg
     3241 acaggctgtt gtggctcggc tggttgttcc ggcgctggtt tcacttcttc taccggtgca
     3301 ggttcacgtt gccccacaca cccggcgaga aacatcgcca gcgcggtaat caaggcgtag
     3361 cgactcattt ttgtcatcaa gattcacccc ttacaaatat agataaagtc tgactttgtg
     3421 cgcccccaga aaattggcgc tgccgtacag cgttaccgcc gaatgtgcgg gaatgctaac
     3481 gctgcgtggc ctttccagag gatgcatctc cagccctctg gcgtcatacc agtaaaaacg
     3541 ataatgaacg gtaacgggtt cttgcctttc gttataaagc gttgaggatg ctgaaggttg
     3601 aatatcagac gtcgaaagga cgggcttttc tgcactgatg cccgcagcca ataaagatga
     3661 ctccatcacc agcgattgct catcattcac cggaatttcc ggatgtgaac gacagcccac
     3721 cagcagtaac aacgccagag acaccagccc aaagcatcct tttctcatcg ttacagacct
     3781 ttatgcgcca gcattggtcc cagcggacgg ccacccaaca agtgcatatg gatgtggtaa
     3841 acctcttgtc cgccatggcg gttggtattc atgatcagac gatagccatc ttcggcaata
     3901 ccttcttgct cagcaatttt tgccgctacg gtgatcatgc gtcccagcgc ctgctcatgc
     3961 tcagctgaga cgtcgttcac agtcggaatg aggatattcg gaatgatcag aatatgcgtt
     4021 ggcgcttgcg gcgaaatatc gcgaaacgcc gttaccagat catcctggta gacgatatcg
     4081 gaggggatct cacgacgaat aattttgctg aatatagttt cttctgccac gacattttcc
     4141 tttttcaaat agccatgcgt tgcgccatgc tacgccgcgc cacactgcga gtatagagta
     4201 tggtcgagtt aaacctgctc tttcaacctt aactcacgat ttcttaagca aaaaatcgtt
     4261 ttgctgccgt atatatcgcc attattccca tttctgcctg cgaatgcgct gaaaagacat
     4321 tctctgtttg gtttacacga caaatatgaa tgcgtatatt tctcatttgc atttacaaac
     4381 aaaattattc gcacactaaa tataatcgct catcaccctc ctccggcatg agcctgacga
     4441 caacataaac caagagattt caaatgcttt caacacaatt taacagggat aatcaatatc
     4501 aagccatcac caaaccgtca ctacttgccg gttgcatagc actggcacta ttaccttctg
     4561 ccgcttttgc tgcaccagcc actgaagaaa cggtgattgt tgagggttca gccacagctc
     4621 cagatgatgg cgaaaatgat tacagcgtaa cgtctacctc tgcgggtacc aaaatgcaga
     4681 tgactcaacg tgatattcct cagtcggtca ctattgttag ccagcagcgg atggaagatc
     4741 agcagttaca aacgctgggc gaagtgatgg aaaacacgca ggggatcagc aaaagtcagg
     4801 cggattccga tcgtgctctt tattattccc gcggattcca gatcgataac tatatggttg
     4861 atggtatccc cacctatttt gaatcgcgct ggaatctggg cgacgcactt tctgatatgg
     4921 cactctttga acgcgtagaa gtagtgcgtg gcgcgacagg actcatgacc gggacgggta
     4981 atccatctgc ggcaattaat atggttcgaa aacacgcgac cagtcgtgaa tttaaaggcg
     5041 atgtctcggc ggaatacggt agctggaaca aagaacggta tgtggcggat ttacaaagcc
     5101 cactcaccga agacggtaaa atccgcgcgc gaattgtcgg cggctaccag aataacgact
     5161 catggctgga ccgctacaac agtgaaaaga ccttcttctc gggcattgtc gatgctgatt
     5221 taggcgatct tacgacgctt tcagccggtt acgaatatca gcgcattgat gttaatagcc
     5281 ctacctgggg cggtttaccg cgctggaata ctgatggcag cagcaacagt tacgatcgtg
     5341 cacgcagtac cgcacctgac tgggcgtaca acgataaaga gatcaacaag gtctttatga
     5401 ccctgaagca gcggtttgct gatacctggc aagcgacact gaatgccacc cactctgaag
     5461 tcgaatttga cagcaaaatg atgtatgtcg atgcctatgt aaacaaagcg gatggtatgc
     5521 tggttgggcc atacagtaat tatggacctg gctttgatta tgtcggcggc accggttgga
     5581 acagtggcaa acgtaaagtt gatgcgctgg atttgttcgc tgacggtagt tatgaattgt
     5641 ttggtcgtca gcacaatcta atgtttggtg gcagttacag caaacaaaac aatcgttact
     5701 tcagttcatg ggccaacatc ttcccggatg aaattggcag tttctacaac tttaatggca
     5761 atttcccaca aaccgactgg tcaccacaga gcctggcgca ggacgatacc acacatatga
     5821 aatcgttata tgctgccact cgtgtcaccc ttgccgatcc gctgcatctg atcctcggcg
     5881 cacgttatac caactggcgg gttgatacgc tgacttacag catggagaaa aaccacacca
     5941 cgccttacgc tggtctggtg tttgacatca atgacaactg gtcgacctac gccagctata
     6001 cctctatttt ccagccgcaa aatgatcgtg acagttcagg caaatatctg gctccaatca
     6061 ccggtaacaa ctacgagctg ggtctgaaat cggactggat gaatagccgt ctgaccacca
     6121 cgttagccat cttccgtatt gagcaggata atgtcgctca gtccaccggt acacctatcc
     6181 ccggcagcaa cggcgaaacc gcctataaag cagtggatgg gacagtcagt aaaggggtgg
     6241 aatttgaact caacggcgca attaccgaca actggcagct gacatttggc gcaacgcgct
     6301 atattgcaga ggataacgaa ggaaacgccg ttaatcctaa tctgccacgc accacggtta
     6361 aaatgttcac cagctatcgg ttgcctgtca tgccagagtt gacagtcggc ggtggtgtta
     6421 actggcaaaa tcgcgtgtat accgacaccg tgacaccgta tggcaccttc cgcgccgagc
     6481 aaggtagcta cgcgctggtg gatctcttca cccgctacca ggtgacgaaa aacttctcgt
     6541 tacaggggaa cgtcaataac ctgttcgaca aaacctacga taccaacgtg gaaggttcta
     6601 tcgtctacgg cgcaccgcgt aatttcagca ttaccggcac gtatcaattc tgaataacac
     6661 ctgtaaaaaa ggcagccatc tggctgcctt agtctcccca acgtcttaca gattagtggt
     6721 tacggatgta ctcatccatc tcggttttca ggttatcgga tttagtaccg aaaatcgcct
     6781 gaacaccaga accagcaacc actacgcccg ctgcgcccag tttcttcagg ccggcctgat
     6841 ccactttaga cacatcagca acgctgacgc gcagacgggt aatacatgcg tcgaggttag
     6901 taatgttttc tttaccacca aatgcagcaa ccagagccgg tgccatttcg ctggtacctg
     6961 tcgcttttgc atcttcagtc gcgtcttcac gacccggcgt tttcagatcc agtgctttaa
     7021 tcagcacgcg gaagatggtg tagtaaacaa tcgcataacc gataccgacg atcgggaaca
     7081 gccacagttt gctgctgtta ccagacagaa cgatgaagtc gatcagaccg tgcgagaacg
     7141 acgtaccgtc acgcatcccc agaagaatac agattgggaa tgccaggcct gccagaatcg
     7201 cgtggatgat gtacaggatc ggcgcaacga acatgaagga gaactcgatc ggctcggtga
     7261 taccggtcag gaacgaggtc agcgccgcgg agatcataat accgcccact ttcgcgcggt
     7321 tttctggttt agcagagtgc cagatagcaa ttgcggcagc tggcagaccg tacattttga
     7381 acaggaagcc accagacagt ttacccgcag tcgggtcacc cgccatataa cgcggaatgt
     7441 cgccgtggaa aacctgacct gctgcgttgg tgtattcacc aatctgcatc tggaaaggta
     7501 cgttccagat gtggtgcaga ccaaacggta ccaggcaacg ttcgatgaaa ccgtaaatgc
     7561 caaacgcaac taccgggttc tggtaagcag cccactgaga gaaggtctgg attgcagaac
     7621 caatcggcgg ccaaatgaag gacagcacaa cgccagtaaa gatggcagcc aggccagaaa
     7681 tgatcggcac aaagcgttta ccggcaaaga agccaagata ctcaggcagc ttaatacggt
     7741 agaaacggtt aaacatgtac gctgcgatcg caccggagat aatccctccg agtacgccag
     7801 tatccgccag gtgtttagag gcgatttctt cagcaggtaa atgcagtacc agtggcgcaa
     7861 ccacggccat ggttttaacc atgatgccat aggcaacaac tgcggccagc gcggatacgc
     7921 catcgttatt ggtaaagccg agggcgacac cgatcgcaaa aatcagtggc atgtttgcaa
     7981 agacggaacc gcctgcttct gccataacat gcgatacaac ggcgggcagc cagctgaaat
     8041 tcgcggaacc gacgcccagc agaatacctg cgataggcag tacggatacc ggcagcatca
     8101 gcgatttacc gaccttttgc aggttagcaa atgcattctt aaacataatt gagagtgctc
     8161 ctgagtatgg gtgctttttt tacgttctca cgcgtggcaa ggggggagag cctcgccgtg
     8221 tacagggcat ctaagcgccc tttatttatt acacagagta aaataattca gtgccaattt
     8281 gtttgacggc tatcacgttt caacttcaga tcattggaga agttgcacat tttgacaaaa
     8341 catatgtcac aatatttcaa acgtggttat tcaccgccca attttcggcg gtgaacttta
     8401 ctcgttttag ccattaatta cgagctttaa aaaaactcat tcaacggatg gattgaaggc
     8461 gggaagcgtc gatgtgaaac agacgggcga agttatcggt ggttacctgc gccagttctt
     8521 caacggcaac acctttcaac acagccatgt attctgcaac gtcacgaacc atcgcaggtt
     8581 gattctcttt tcctcgatgc ggtaccggcg caaggtaagg tgagtcagtt tccaccagta
     8641 atcgatccag ggggacataa cgcgcagcat cgcgcagttg ctccgcatta cggaaggtca
     8701 caatgccgga aaaggagatg taaaatccga gatccagtaa tttacccgcc gtttctctgt
     8761 cctctgtaaa acagtgtagt acgccaccgc aatccgtcac tttttcttcg cgcagaattg
     8821 ccagcgtatc ggcacgggcg tcacgggtat ggacgataac cggcttgttc agttcacgac
     8881 caatctggat atgatggatg aaggactctt gctgacgtac tttagtttcc ggtgtgtaat
     8941 aataatccag cccggtttca cccagcgcta caacaccctc ttctgccgcc agacggcgta
     9001 aatcttctac atcgtaggga tcattctggt tgagtggatg cacgccacaa gaaaatacga
     9061 cgttgtcacg ttcgcctacc agatcccgca tatgtaaata acccggtaat gttgtggcga
     9121 ctgccagaca aaatttcaca tcgcgtgcgg cggctttcgc cagaacgtca tccacgtcct
     9181 tatgcaaaga ttcataatcc agaccatcga gatggcagtg tgagtcgact aaaaacatga
     9241 tgtctctctt aaagatgagg aaccggtagc acaacgcccg gttgcaggta atgctcaata
     9301 cgcagtaaaa gatcggtgat gagaagctcg cggttgatgc ctgtaacaga cattaactgt
     9361 tcacgaatgt ggcaaacatc ccccagtata gcctgcaggc gcgagggaga aagatggttt
     9421 gccagttcgg cgaccaggcc cggcacatca acattagtca cctgcgcagc accatgatgg
     9481 cgttttagcg catccatcag caacgttgcc agccagtgta aacgcgccgg agcttgttca
     9541 tgattaaggg ccgctagcag cgaataccag tcgcccgatg gcacgctata tgccaacgcc
     9601 tgacacaatg tttcacgagc ctgccagtta tctccctgaa acaacgccag tgccgcgcca
     9661 ggcgaaccgg cgcttaagcg caatgcggca agtaatgcat cctgtgacat tgtcacttcg
     9721 cgtgaaagcc aggtcacggc gtactgttcc ggcggcggcg caaggtaatg taaccgacaa
     9781 cgactacgta atgttgccag taaacgttca ggctcgcggg tagccaggaa aaaccaggtt
     9841 tctgctggtg gctcttcaag cgttttcagc aatgcgttag ccgcggcgtc ggtcagtaag
     9901 gcagcatcgg ttacccagac aactttcgca ccacctaagc gtgcgtgctc attcagcttt
     9961 tcggtgacct cacgtaccgc atcaatgccc agcatatttt tccctttttc gggagccagg
    10021 gtgtagtaat cgggatgcgt gccagcctgc atcaactgac atccacgaca gtgaccgcaa
    10081 cttttgtggc cctgcggttg ttggcagagt aaataacggc tcagggcgta gattaaagca
    10141 tcatcgccca tgcccggtaa cgcctgaatg agtagcgcat ggtgacctct tccggcctga
    10201 tagctggcta ccagtttttc gaaatcaggt cgtaaccatg gataccatct catgcgtcca
    10261 actccttaac ccagtgggtc acggtagtgc ggattgcatc catcacggcc tccagcggct
    10321 gggtggcatc aatggtatga atacttttat cttgtgcagc cagttccaga tagcgggcgc
    10381 gggtgcgatt aaagaaatcg aaagactctt gctcaatacg atccagctcg ccgcgcgcac
    10441 gcgcgcgttt taagccaact tccggggtaa catcgagata gagcgttaag tcggggcgaa
    10501 aatccccgag aacagcatca cgcagtgttg ccagcatatg ttggtcaata ccacgtcctc
    10561 cgccctgata cgcctgagtg gagagatcgt ggcgatcgcc aatcacccag gtgccgttag
    10621 ccagagctgg tttgatgacc gtttctacca gttgaacgcg cgcggcataa aacatcagaa
    10681 cttcggcttt atcggtaatg acttcatcgc ctaccgattt gatatccagc accaggcttc
    10741 ttaacttttc ggcaagttgc gtaccgccag gttcccgagt gaaaaccatg tcgcggatac
    10801 ccagttgctc aagcgtctca accaccacat tacgcgcggt agttttgcct gcgccttcca
    10861 gcccctcaat gacgatatac ttactgcgca tttttttcct taagcacttt cagataatcc
    10921 tgcacagact tgttatggct ggcaagattg gtattaaacg tgtgaccacc tttaccatcg
    10981 gccacaaaat agagatacgg cgtttttgcc ggatgcgcag cagccttcag cgaatccgcc
    11041 cccggcgtag ctatcgcacc cggcggcaaa ccggtaatgg tataggtgtt atacgctgtc
    11101 ggcgtttcca ggtctgcacg agaaagtttg ccattataac gctctcccat cccgtaaatc
    11161 acggttgggt cggtctgcag gcgcatacca atgcgtaaac ggttgataaa taccgaggca
    11221 acctgatcgc gttcactggc aacggcggtt tctttttcga taattgatgc catcgtcacc
    11281 agctgatttt tatctttata aggcagaccg tccgcacgcc cttcccaggc gctatcgacc
    11341 gctttcacca ttttcttgtg cgctcgcttg agtaacgcga catcggtggt attggcggta
    11401 tacatccagg tgtctggcca gaaccaacct tcaatccact ccgggttttc cagttcaagt
    11461 gcctgcgcta cggtggcgta cttatcgtcg ctcagcgtat gcttgatata cggggcctca
    11521 cgcaattgct tgaggtaatc gctcagacgc atcccttcta ccagtcgcag agggaactgt
    11581 gcttctttac cgctttccag caacttcagc atctcgcgca cggtcatctg cggtgtaaag
    11641 cggtaagtcc cggctttaaa gtgagaaaga tccggttcga tacgcagcag ccattgaaaa
    11701 acccgtgggc gattgatgat cttatcagca taaagctgtt caccgagcgc cagacgtccg
    11761 gtccctggct tcagggtaaa tatcgtctct tctttgataa gcaatttgct gtcggcaaga
    11821 tggcgaacct tccagacgcc cacaccagcg gcgataccca gtaccaccag caataacaag
    11881 attatcaata acactttttt catgactaat tcgggcgctc acaaagtggg gctaaatatt
    11941 catataacgt tgctgacgaa aaggagacat cgccacaggc acgtacgggc atcactggca
    12001 ttaacgcatt acaaataacc atctcatctg cctgcaacgc ctcttccaga gaagcttgca
    12061 cttcgacaag ctgataagag gattgtgcca gcaaacggat acagaattgt cgcataatgc
    12121 cgttaacacc tgcctgatcc agtcgcggcg tataaactac gttgcccttc cgccagaaca
    12181 aattagccgc acagcattcc gtaacccacc cttcgctgtc aaggaccagc gcctcatcag
    12241 cgtttgtctg ctcaagatga gagcgaatca atacttgctc aagacgattg agatgtttaa
    12301 tacctgcaag atgaggattg cgccccagcc gcaccgggct tagcgccaac gtcatcccct
    12361 cgttacgcaa acggtcgtaa tgtgcaggat aagccgtaac ggagagaatc cgcgttgccg
    12421 gtccactgtt caatgtgctg taccctcgcc cgccactacc gcgactgatc acgactttca
    12481 gtacaccatt ttgctgttct gctgcaagcg ttttcatctc ttgttcaagc tgtggccaga
    12541 agtcacagga aatcatcaac cgctgacaag catcctgtag tcgctggata tgcgccgata
    12601 acaaactgac tttaccgtcg ataactctgg cggtggtaaa acaaccatca ccaaactgcg
    12661 ttgcccgatc gcttactgcc agcgattcct gcttataacc gttaattaag aacataccgg
    12721 ctccttatca gagaattgtt agtgtggcag catgttcact acggaacaag tcggaataaa
    12781 agctaagaaa aaaggcccgc aagcggacct tttataaggg tggaaaatga caacttagat
    12841 ctttttaaag atcaaagaac cattagtgcc accgaagccg aaggagttac acagcgtgta
    12901 ttccattccg ctgacctgac gtgcttcatg cggtacgaaa tccagatcgc aaccttcatc
    12961 cgggttatcc aggttgatgg ttggcggaac agcctgatcg cgcagcgcca ggatggagta
    13021 gatagattct actgcacccg ccgcacctaa cagatgaccg gtcatagatt tcgtggagct
    13081 taccaacaca cggcttgcag cttcaccgaa gatggttttc accgcctgcg cttcagcttt
    13141 atcgccagcc ggcgtagaag taccgtgcgc gttaacgtag ccaatctgac tcgcttcaat
    13201 gcctgcatca cgcagagcat ttgccattgc cagagctgcg cctgcgccat tttctggcgg
    13261 tgacgtcata tgataagcat cgctgctcat accaaagccg acgagttcag cgtaaatttt
    13321 cgcaccgcgt tttttcgcgt gttcgtactc ttcaagtacc agcataccgg caccatcgcc
    13381 cagtacgaag ccatcacgct ctttatccca cgggcggctc gccgcttgcg ggttatcatt
    13441 gcgggtagat aatgcacgtg ccgcgccaaa accaccaacg cccagcggcg tactggcttt
    13501 ctctgcgcca cctgcaacca tcacgtcagc atcgccatac gcgataatac gcgcagcatg
    13561 accaatgttg tgcacgccgg aagtacaggc ggtcgcgata gagatgcttg ggccacgcag
    13621 gccatacatg atagtcagat gacctgccac catgttcaca atcgttgacg gaacgaagaa
    13681 tgggctgatc ttacgtggac caccgttcat cagagatgtg tggttttctt cgatcagtcc
    13741 gaggccgcca atcccggagc caattgcggc accaatgcgg gttgcgttct cttccgttat
    13801 ttcaaggcca gaatcctgca tggcctgaac gccagcgaca attccatatt gaatgaaggc
    13861 atccatcttg cgctgttctt tgcgcgagat aatgtcctca cagttaaaat cctttactaa
    13921 gccagcaaat ttcgttgcat aggcgctagt atcgaaatgg tcgattaggc tgatgccact
    13981 ctgaccggca agcagagctt tccaggtaga ctctacggta ttgccgacag gagacaacat
    14041 gcccagtccg gtcacaacta cacgacgctt agacacgttt gtcctccagg gagggaaaaa
    14101 atgattctag tgggacaaaa agataaaact caggcggtcg aacgaccgcc tggagatgtt
    14161 cacttacgcc tggtggccgt tgatgtaatc aatggcagcc tgaacggtgg tgattttctc
    14221 agcttcttcg tccggaatct cagtatcaaa ctcttcttcc agagccatta ccagctcaac
    14281 ggtgtcaaga gaatccgcgc ccaggtcttc aacgaaagaa gcattgttgg taacttcttc
    14341 ctgcttaacg cccagctgtt cgccgataat tttcttaacg cgttcttcga tagtgctcat
    14401 actcttaaat ttcctatcaa aactcgcttt cgcgatggtt ttcgtagtgt ataaaatgtt
    14461 gaaaaatttg caactaaatc ccggcaggtc ttaccacgat tttacgttat tttgaggcct
    14521 taccccccaa taacgcaaat cattttgcac taattattac tcataaccac gcagactgcg
    14581 cgcaacatga gcattttgtg caaatcgcgg tcagaccatg tacatcccgc cgttcacatg
    14641 caaagtttca cccgtgatgt aagctgcttc gtcggatgcc aggaatgcaa ccgcgttggc
    14701 gatttcctgt gcgccgccga ggcgacccgc aggaacctgc gccaggatac ccgcacgctg
    14761 gtcatcgctc agcgcacgtg tcatgtccgt ttcaataaag cccggagcaa caacgtttac
    14821 agtaataccg cgtgacgcaa cttcgcgcgc cagtgattta ctgaagccga tcaagcccgc
    14881 tttcgccgca gcgtagttgg cctgaccgcc atttcccatg gtaccaacca cagaaccgat
    14941 agtgataata cgaccatgac gctttttcat catagcgcgc attaccgctt ttgacagacg
    15001 gaaaacagat gaaaggttgg tttcgataat atcgttccac tcttcatctt tcattcgcat
    15061 taacaggtta tcacgagtga taccggcatt attgaccagg atatccactt caccaaattc
    15121 tgcgcgaatt ttttccagaa cagattcgat agatgccggg tcggtcacat tcaacatcag
    15181 acctttgccg ttggcaccta aataatcact gatcgcctga gcgccatttt cactggtcgc
    15241 agtgccaata actttcgcgc cacgggctgc gagcgtttca gcaattgcgc ggccaattcc
    15301 gcggcttgca ccggttacca gtgcgatttt tccttcaaaa ttcatgattt tcctctttta
    15361 aagctcgagc gccgctgcca tcgctgaagg ttcgttcagc gccgaggcgg tcagggtgtc
    15421 gacaatgcgt ttcgtcaggc cagtaagcac tttgcccggg ccgacttcat agagatgttc
    15481 tacgccttgc gctgccatgt actcaacaga cttcgtccac tgaaccgggt tatacaactg
    15541 acgtaccagt gcgtcacgga tggcatcacc attggtttcg catttcacat caacgttatt
    15601 cacaacagga actgttggtg cgttaaaggt gattttcgct aattctactg ccagtttgtc
    15661 ggctgctggt ttcatcagcg cacagtgaga cggtacgctc actggtaacg gcagagcgcg
    15721 ttttgcgccc gcagctttac aggcagcgcc agcacgctca accgcttctt tatgaccggc
    15781 aataaccacc tgtcccggag agttaaagtt taccggagaa acgacctgac cttctgcagc
    15841 ttcttcacac gctttcgcaa tagacgcatc atccagaccg atgattgccg ccatagcgcc
    15901 cgtgccttcc ggtacggctt cttgcataaa cttgccgcgc atctcaacca gacgcaccgc
    15961 atcagcgaaa tcaatcacac cagcgcaaac cagcgcggag tattccccca ggctgtgacc
    16021 ggccatcatt gccggtgctt taccgccctg ctgctgccat acgcgataca gcgcaacaga
    16081 ggcagtcaac agcgcaggct gagtttgcca ggttttattc agttcttcag ctggcccctg
    16141 ctgggtcagc gcccacaggt cgtagcccag cgccgcagaa gcttcagcaa acgtttcttc
    16201 gacaattgga tagctcgccg ccatatcagc cagcattcca acggtttgag aaccctgtcc
    16261 agggaacaca aatgcaaatt gcgtcatgtt ttaatcctta tcctagaaac gaaccagcgc
    16321 ggagccccag gtgaatccac cgccaaaggc ttcaagcaga accaactgcc ccggcttaat
    16381 gcgcccgtcg cgtacagctt catccagcgc gcacgggaca gaggccgcag aggtattacc
    16441 gtggcgatcc agcgtcacca cgacattgtc catagacata ccgagttttt tcgccgttgc
    16501 actgataata cgcaggttag cctgatgcgg aaccagccag tccagttgag aacggtcaag
    16561 attattcgcc gccagcgtct catcaacgat gtgcgccagt tccgttaccg caaccttgaa
    16621 gacttcgttg cccgccatcg tcagatgaat tgaattctct ggattcacgc ggtcggcgtt
    16681 tggcagcgtc agcaattcac cataactacc gtcggcatgc agatgggtgg aaatgattcc
    16741 cggctcttca gaggcagcca gcaccgcagc gcccgcgcca tcgccaaaaa taataatagt
    16801 cccacgatct gttggatcgc aggtgcgcgc cagtacatcg gaaccgacga ccagagcata
    16861 cttcaccgcc ccagatttca cgtattgatc ggctacgctt aatgcatagg tgaaacctgc
    16921 gcaggctgct gcaacgtcaa atgccgggca acctttaatg cccagcatgc tttgaatctg
    16981 acaagctgcg ctcgggaaag cgtgcgtagc agaagtcgtt gccacaacga tcaggccaat
    17041 ctggtctttc tcaatgcccg ccatctcaat tgcgcgtgtc gccgcttcaa agcccatggt
    17101 tgaaacggtt tcgtttggcg cggcaatgtg gcgttcgcgg ataccggtac gagtgacaat
    17161 ccactcgtca gaggtgtcca ccattttttc caaatcggcg tttgtccgca cttgttcggg
    17221 cagatagctg ccagtaccaa taatcttcgt atacatgtac gctcagtcac ttttcggtta
    17281 tataccgtca cttgcaaact gcgagttcgc tggcagcgtc ctgctaccgc agagttccgc
    17341 ttttgccacc gtccagcagc tcaaaaccag ctgggtatac agattccagg cgagcggcaa
    17401 ttcgctgagg aacttgtcgc tgcaccgcct gcactgcctg ttcaatcgcg accgcaaaag
    17461 ctcgctgatt ggctgcacca tgacttttta tcaccgtgcc gcgcaatcct aacagacagg
    17521 cgccgttata ctggtcgggg ttgaggtgac tgaatcgcct cgtcaggctc ttttgtagcc
    17581 aacgctttaa taacagtagc caccacgacc gttttttccc ttcaccctga gatttcagca
    17641 gagaaaggaa catcctgaca acaccttcca tcgtctttaa tgtgacattt cctgtaaagc
    17701 cgtcacaaac cagcacatct gtcttgccag ttaacaactc attggcttca agatagccga
    17761 tataattgat agaagggatt gttttaagca ccgctgaggc atcccgaata ctgtcgagac
    17821 cctttacttc ttcttcacca atattgagca acgccacgcg aggattggga atttccacca
    17881 cctcttcagc cagaactgag cccataatgg caaattgcac caacattgtg ctgtcacaat
    17941 cgacgttggc ccctaagtca aggaccaccg ttttgccctt ttgctgatgt ggtaataccg
    18001 tcaccagcgc cggacgctca atcccctcca ggggcttgag taataatttt gccagcccca
    18061 tcagtgcccc ggtattaccg gcactgacac aggcttgcgc tcgaccttct ttcaccagct
    18121 ccagggccac gcgcattgaa ctcccacgac tggcgcggat agcttgcgaa ggccgggcat
    18181 cactggcgat aactgactgc gcaggaataa tctgcagacg cgaacgttgt tcaaagtcag
    18241 ctttagcaag taatggcgtg atggcgtcgg gattgccgac taaaagaaga gtgagttgcg
    18301 aattagaatt cagtgcctgc aatgctgcag gcactgtcac ggaagggcca aaatcccctc
    18361 ccatgacatc taacgccagg gttagacgtg tcaaggtatc gtcgccgccc ggtttggtct
    18421 ttccccagtt gcctggggaa aatcctcact aagcttcatc acgcagacgc gtgattactt
    18481 agcgatgacc ttgcggccgc ggtagtaacc gtcggcagtg atgtggtgac gcaggtgttt
    18541 ttcaccagaa gttttgtcta cagacaggct ggtgactgcg gtcagcgcgt catgggaacg
    18601 acgcatgcca cgtttggaac gggttggttt attctgttgt acggccatgg accttactcc
    18661 tcaattacgg tttatccccg atccaacggg gagcaccaat tacttacgct ttaagctggc
    18721 taatacggca aatgggtttg gcttttgcgc ttcttcaggc agttcaccaa agaccatgtc
    18781 cgcttcggac acttcacagt gttcagaatc atgcaccgga actaccggca aggcgaggat
    18841 gatttcatct tcaaccattg caagcagatc gatttcaccg aattcgttaa cctcaatcgg
    18901 ttcatacgct tccggcagtg cttcagcctg ttcgtctgaa cgcacaggac taaaacaata
    18961 cgttgtgtag acctgatgag taaacggctt cccgcaacgc tgacactcga gcgttaccgt
    19021 caccttcgca tcgccgttta acactgcgag acgttggtta tcgatagcga acgacatgga
    19081 gcattccaca tcactgtcca cactgactac ggattcggcg acgcgctcaa cctgatcagg
    19141 ggtatagata ccctggtaat caaggcgttt ttgagccgta cgaaccggat cgagagtcag
    19201 gggtaatttt accttttgca tagggcgcgc atattaactt tgtaacgtca tagagtcaaa
    19261 gaaaaaggca gcctgtggtt gccttttgcc aataattcgc acacattgcg ggttactgct
    19321 ttattttcgt tcagtgctga taacgaacat caacctgcaa aacgaagcgc atagtttaaa
    19381 atggctatca tcaatacgct atatctgatg gaaaaaaata tgcctaaact tattttagcc
    19441 tccacctcgc catggcgtcg cgctcttctg gaaaaactgc aaatctcttt tgaatgtgca
    19501 gcaccagagg tcgacgaaac cccacgcagc gacgaatcac cgcgacagtt ggtgcttcga
    19561 ctggcacaag aaaaagcgca atctctggcg tcacgttatc cggatcattt aattattggt
    19621 tcagaccagg tatgtgttct tgatggcgaa atcaccggta aaccgttaac ggaagaaaat
    19681 gcccgtctgc aattacgcaa agccagcggc aatatcgtca ccttctatac tggactggcg
    19741 ttgtttaatt cggcgaatgg gcatctgcaa acagaagtgg agccttttga cgtccatttc
    19801 cgtcacctga gcgaggcgga gattgataat tacgtgcgta aagagcatcc cctgcactgc
    19861 gcgggtagct ttaagagtga aggatttggc attacgctgt ttgagcgttt agaggggcgt
    19921 gatcctaaca cgctggttgg tttaccgcta atcgcgctgt gtcagatgtt acgtcgggaa
    19981 gggaaaaacc cgctgatggg atagtttttt gcgccggatg cggttacttc gcatccggca
    20041 atcggtgctg gcggcctgat gcggcgtaaa cgccttatca ggccaaccgc ccattatcag
    20101 gcttatctgc ttgtattagc gcgcgttacg cagcttttgc aaacaacgtt tcaaaccttc
    20161 atccatcggc gcttcgatac gcatcacctc accggtcccc ggatgggtaa acttcaacgc
    20221 tgcggcgtgc aggaacagac gatttaatcc cgtgcctgct tcagtgagct gtctgtcaaa
    20281 ttcacggtca ccgtagcgat cgtcaaaggc aatcggatga cccgcatact gtgtatgcac
    20341 acggatctga tgagtacgtc cggttaccgg gctacaacgc accagggtgg caaatgcata
    20401 gcgttcttcc actttaaagc gtgtttccga cggtttgcct tcctgactga cacgcacgat
    20461 acgttcgccg ctttgcagaa tatttttcaa taacggcgct tgaacgctct tcacatgcga
    20521 ctgccactga ccgcgcacca gcgccaggta atctttttgc attccttttt cacgtaattg
    20581 ctcatgcaga gaacgcaacg ccgagcgttt tttcgctacc agcaacacac ctgaagtgtc
    20641 ccggtcgaga cgatgaacca gttcaagaaa ccgcgcttcc gggcgcaacg cccgcaaacc
    20701 ttcgataacg ccgaagctta aaccactgcc gccatgtacc gccgtaccgg aaggtttatt
    20761 cagcaccagg atatgatcat cttcatataa gatgacgtcc gccagcgccg ccaccttttg
    20821 cagatgtggc gaaaccgcct cttcttcccg ctcagcaacg cgaaccggtg ggatacgcac
    20881 ctcatcaccc gcttcgagtt tatattcagg cttaatacgt tttttgttca cccgcacttc
    20941 gcctttacgc aaaatacggt aaatcatact ttttggtacg cctttcaatt gggtacgcaa
    21001 aaagttatcg atacgttgcc ccgcttcgtc agcggtgata gcaacaattt ttacggatgg
    21061 agtctctgtt ttcatggtgg gcgattctaa ttagccaaca ggattcgcgc cactcatttt
    21121 tctatgctta tatttagttt tgcaccttat tacttcacta cgtgatcact ttattgatgg
    21181 ttattaaacc aatcaccagc aagaagtgaa aaaactgtga gtaagcgggt gataaatggt
    21241 aaaagtcatc ttgctataac aaggcttgca gtggaataat gaggccgttt ccgtgtccat
    21301 ccttgttaaa acaagaaatt ttacggaata acccattttg cccgaccgat catccacgca
    21361 gcaatggcgt aagacgtatt gatctttcag gcagttagcg ggctgcgggt tgcagtcctt
    21421 accggtagat ggaaatattt ctggagagta atacccagtc tgtttctttg ataattgcgc
    21481 tgtttttccg catgaaaaac gggcaaccga cactctgcgc ctctttgagc tgacgataac
    21541 cgtgaggttg gcgacgcgac tagacacgag gccatcggtt cacacccgga aaggcgttac
    21601 tttgcccgca gcttagtcgt caatgtaaga ataatgagta agttacgatg aaaagaatgt
    21661 taatcaacgc aactcagcag gaagagttgc gcgttgccct tgtagatggg cagcgtctgt
    21721 atgacctgga tatcgaaagt ccagggcacg agcagaaaaa ggcaaacatc tacaaaggta
    21781 aaatcacccg cattgaaccg agtctggaag ctgcttttgt tgattacggc gctgaacgtc
    21841 acggtttcct cccactaaaa gaaattgccc gcgaatattt ccctgctaac tacagtgctc
    21901 atggtcgtcc caacattaaa gatgtgttgc gtgaaggtca ggaagtcatt gttcagatcg
    21961 ataaagaaga gcgcggcaac aaaggcgcgg cattaaccac ctttatcagt ctggcgggta
    22021 gctatctggt tctgatgccg aacaacccgc gcgcgggtgg catttctcgc cgtatcgaag
    22081 gcgacgaccg taccgaatta aaagaagcac tggcaagcct tgaactgccg gaaggcatgg
    22141 ggcttatcgt gcgcaccgct ggcgtcggca aatctgctga ggcgctgcaa tgggatttaa
    22201 gcttccgtct gaaacactgg gaagccatca aaaaagccgc tgaaagccgc ccggccccgt
    22261 tcctgattca tcaggagagc aacgtaatcg ttcgcgcatt ccgcgattac ttacgtcagg
    22321 acatcggcga aatccttatc gataacccga aagtgctcga actggcacgt cagcatatcg
    22381 ctgcattagg tcgcccggat ttcagcagca aaatcaaact atacaccggc gagatcccgc
    22441 tgttcagcca ctaccagatc gagtcgcaga tcgagtccgc cttccagcgt gaagtccgtc
    22501 tgccatccgg tggttccatt gttatcgaca gcaccgaagc gttaacggcc atcgacatca
    22561 actccgcacg cgcgacccgc ggcggcgata tcgaagaaac cgcgtttaac accaacctcg
    22621 aagctgccga tgagattgct cgtcagctgc gcctgcgtga cctcggcggc ctgattgtta
    22681 tcgacttcat cgacatgacg cctgtacgcc accagcgtgc ggtagaaaac cgtctgcgtg
    22741 aagcggtgcg tcaggaccgt gcgcgtattc aaatcagcca tatttctcgc tttggcctgc
    22801 tggaaatgtc ccgtcagcgc cttagcccat cactgggtga atccagtcat cacgtttgtc
    22861 cgcgttgttc tggtactggc accgtgcgtg acaacgaatc gctgtcgctc tctattctgc
    22921 gtctgatcga agaagaagcg ctgaaagaga acacccagga agttcacgcc attgttcctg
    22981 tgccaatcgc ttcttacctg ctgaatgaaa aacgttctgc ggtaaatgcc attgaaactc
    23041 gtcaggacgg tgtgcgctgt gtaattgtgc caaacgatca gatggaaacc ccgcactacc
    23101 acgtgctgcg cgtgcgtaaa ggggaagaaa ccccaacctt aagctacatg ctgccgaagc
    23161 tgcatgaaga agcgatggcg ctgccgtctg aagaagagtt cgctgaacgt aagcgtccgg
    23221 aacaacctgc gctggcaacc tttgccatgc cggatgtgcc gccagcgcca acgccagctg
    23281 aacctgccgc gcctgttgta gccccagcac cgaaagctgc accggcaaca ccagcaactc
    23341 ctgcacaacc agggctgttg agccgcttct tcggcgcact gaaagcgctg ttcagcggta
    23401 gtgaagaaac caaaccgacc gagcaaccag caccgaaagc agaagcgaaa ccggaacgtc
    23461 aacaggatcg tcgcaagcct cgtcagaaca accgccgtga ccgtaatgag cgccgcgaca
    23521 cccgtagtga acgtactgaa ggcagcgata atcgcgaaga aaaccgtcgt aatcgtcgcc
    23581 aggcacagca gcagactgcc gagacgcgtg agagccgtca gcaagctgag gtaacggaaa
    23641 aagcgcgtac caccgacgag cagcaagcgc cgcgtcgtga acgtagccgc cgccgtaatg
    23701 atgataaacg tcaggcgcaa caagaagcga aggcgctgaa tgttgaagag caatctgttc
    23761 aggaaaccga acaggaagaa cgtgtacgtc cggttcagcc gcgtcgtaaa cagcgtcagc
    23821 tcaatcagaa agtgcgttac gagcaaagcg tagccgaaga agcggtagtc gcaccggtgg
    23881 ttgaagaaac tgccgctgcc gaaccaattg ttcaggaagc gccagctcca cgcacagaac
    23941 tggtgaaagt cccgctgcca gtcgtagcgc aaactgcacc agaacagcaa gaagagaaca
    24001 atgctgataa ccgtgacaac ggtggtatgc cgcgtcgttc tcgccgctcg cctcgtcacc
    24061 tgcgcgtgag tggtcagcgt cgtcgtcgct atcgtgacga gcgttatcca acccagtcgc
    24121 caatgccgtt gaccgtagcg tgcgcgtctc cggaactggc ctctggcaaa gtctggatcc
    24181 gctatccaat tgtacgtccg caagatgtac aggttgaaga gcagcgcgaa caggaagaag
    24241 tacaagtgca gccgatggtg actgaggtcc ctgtcgccgc cgctatcgaa ccggttgtta
    24301 gcgcgccagt tattgaagaa gtggctgaag tcgtagaagc ccccgttcag gttgccgaac
    24361 cgcaaccgga agtggttgaa acgacgcatc ctgaagtaat tgccgccgcg gtaactgaac
    24421 agccgcaggt gattaccgag tctgatgttg ccgtagccca ggaagttgca gaacacgcag
    24481 aaccggtggt tgaaccgcag gaagagacgg cagatattga agaagttgcc gaaactgctg
    24541 aggttgtggt tgctgaacct gaagttgtta ctcaacctgc cgcgccagtc gtcgctgaag
    24601 tcgcagcaga agttgaaacg gtagccgcgg ttgaaccaga gatcaccgtt gagcataacc
    24661 acgctaccgc gccaatgacg cgcgctccgg caccggaata tgttccggag gcaccgcgtc
    24721 acagtgactg gcagcgccct acttttgcct tcgaaggtaa aggtgccgca ggtggtcata
    24781 cggcaacgca tcatgcctct gccgctcctg cgcgtccgca acctgttgag taataattag
    24841 ctcaaagtaa tcaagccctg gtaactgcca gggctttttt atttcatgtt tgaatcaaca
    24901 tattaaaatt catcaaatgg catccttgct aaccaacaat gcaaaatagg caaaaaaaat
    24961 gcccgccccg gcgatcccag agcgggcaga caaaacatac ccagtttcat gatatgtttt
    25021 aaagcgagct tatttgttga gctggaagag cgacaatccc tgcatatcgg taaatgcttt
    25081 atacgatgcc tgcaatgccg tttgctgcat gatgtaagat gaaatagttg cattccagtc
    25141 cacatcaacc agatcgctca tctgctgcgt ttgccctaaa gcgcgatcgc tacctaagga
    25201 atccagcgac tccagttcgt tcagctgcgt gcctaattcc gcgcgaacag tcagcacatt
    25261 gttcagcgag tttttcagtc cgcggttggt tttatctaac gccgcagcgg cggtttcttt
    25321 atccgcttcg ctatccgcga ccggcgtttt cagggctgcg atggcactat ccagcatggc
    25381 aaaaagattg gtttcagaag cgctaccgtc tggttccgct accgcgttgc tggtaatact
    25441 gtcgaaaatt ttgtcacccg tgtgccctat caccatcgaa cgcgaagcat cgacctgttg
    25501 tttaatactt tctgctccac cgacgtattt ccctttctct tcgctaaacg gcgcagtctc
    25561 tgttttataa ccggcaaaaa tgtagcgccc gttaccgtca gtggtgttcg ccagattcag
    25621 caactggtca cgaagcccct gaatatccgt agccagcgag gcccggtcat cgtcactcaa
    25681 ggtgccattg ctggcgtaga caattttttc ctgagcattc tggatagcag tggtgacctg
    25741 gctaagtaca ctctcttcca gtgacacttt ttgagtggcg aaagtacgtg ccagcgtgta
    25801 ctggctgttt tgcgcctgtg cctgggagag aactacggct tgtgatgctg caatgggatc
    25861 gtcagaaggg ttaacgactc gcttacccgt cgacatctgc tcgccgtact tcatccattc
    25921 tgcctgagaa ttggtgatgc cgcgcatgtt ttgctggtac atcatctggg tactgaaacg
    25981 cattttatct ccccttagcg aatgttaatc agcgcatcaa aaatcgcgtt tgccgtctgc
    26041 agaacctgcg cattcgccag gtaatactgc tgaaaacgtt gcagatttcc gtactcctca
    26101 tcgagattga caccggaaat cgactgctgc tgattggaaa gctgcgtcac cacattacct
    26161 tgcgtggtgc tactggtttt caacgtcgcg gttttattac cgatatcact cactaacgag
    26221 gcataagcgt cgttaaagga tttcgcaccg cccaccgttt tactgttgct ttgcagatcc
    26281 agcagggcct gaccgttgcg gttgtcgcta tcacccgcat cttcttcgct cgccatcgcg
    26341 attttcgctt cgtcggtgat taatacatcc atgttgacga tggcgtcact tactggtttc
    26401 agcgtgaagc tgtcgttaac ggcaggcgtt cctgtaaacg tcaactccag accatcaaat
    26461 gccactttac cgttggcatc cggcgtcacc gtaaaagtgg tattgctggc aaggcgggtg
    26521 acctgccact gattattatc gaacgagatt ttgtaatctg tcgccagtac cgcggaggca
    26581 tcagttaccg tggcaccgat cgcaacgtca cctttgtttt tcgtgttttg cagaaccgcg
    26641 ggcttaccga tagcaaagaa atcttcacca gcatcgccgt tggcatcaaa tccggctttg
    26701 tgttggctgt tgaaagcctc ggcaaatgcc agcgccagtt gtccaagcgt attacgcgtc
    26761 tggtccagat cctgagaacg gaatgtcaga atgccgccca gcgacccggt attcagtaat
    26821 ttctccggga tctcaatatt gcctgccgtc ccatcaacgt aagcgacagt cgtacgagaa
    26881 gggtcggcgc tggaaggaac tgccgccagt tgccgcgccg tacttccctg aaccagtgag
    26941 taaccattgg ccatcgtgat gttataagta ccgccatcct gaacgctgac ttctacgcca
    27001 acaatctggt ttaattcgct caccagttga tcgcgttgat ccagcagatt gttaggtgac
    27061 gcccctgccc ccacgcctgt caggcgcgag atttgatcgt tcaggctggc aatttgttta
    27121 gcgtaattgt tgatctgatc aacgctggca cctatcgcga tattgacctg tttgtcctgg
    27181 tcgcgcagat attgatcggt ggttttaaac tgattcacca acccttctga tttcccaatc
    27241 agcgcctggc gcgctgccgg gtcttccgcg ttactcacca gcgtttgcag gctggtgaag
    27301 aaatcctgca tctgtgttgc cagcgaagag gtactggtgg agagcatatt gtcgattttc
    27361 gacatctgct catagcgggc ggtcaggccg ctactttgcg tctgcgcagc acgtaactgg
    27421 ttggtaataa acgcatcata ctcacgctgc acaccagaaa cgtagacgcc attgccaacc
    27481 cagccgccag cgcccaacgt gctattggcc tgcgccataa tagtggtttg gcgggtatat
    27541 ccggcaacgt tatagctgga gatattatta cttgccgtat ttaacgccgc ctgggccgcg
    27601 ttcagtccgc tcatggcgtt attgatcaag ctggacatgg aggttcctta taagccttca
    27661 attacagagt attatcggca gcgacccgcc ggacttgagt tattcagaac agattatcaa
    27721 tgttcatgct gtaggttttg ctcaccttgt cgcttatcga tttcatctgc tggatcatgt
    27781 tggtgagttt acgggcatag tgaggatcgg tggcatagcc cgcgtcctgt agggcctgcg
    27841 ccccctgttc cgcactcgcg gcggtcgtca cggcggcgta gcgcgggtta cgcgttaaca
    27901 gcccaacgta atccgacaag gcttccagat acgagctgta gacgcgaaac ttcgctttta
    27961 ctttcttcgc ttcgccgttt tcatattcag tcgtggtgat ttcagtaact ggccctttcc
    28021 agttgccaga ggctttgaca ccaaacaggt tatagctcgg ctcgccgttt tcgcggcgga
    28081 tttgccgttg cccccaacca gattccagtg ccgcctgagc gaggatcaaa tgatgtggca
    28141 caccgctttg ctggcttgcc agttgggcgg gcagcgagag ttgcgcgagg aatgctttac
    28201 tgtcacccgg cagcgaatca tcgtagttac gtggcacggc cttttgcacc agctgcgaaa
    28261 gcgcctgatt ttgataacgc accacggttt cgagcgggaa tttcatcggt gctgctggcg
    28321 tggactcctc tggcaatggt tgttctggcg tcatctgttt aaccatcatc tctgcaagcc
    28381 ccagaccttt gcccgccgtc atctgttggg caatctgctg gtcatacata ctggtataca
    28441 gacgagtgtg ctcgctgctg aacaggccat cttttggtaa agcgtcgcgc atgcttttca
    28501 acatcatctg cacgaacatc ccttccacct ggcgggccac cggacggata tttgccgccg
    28561 gatcttcgcc cgctttcgcc tttagttcgt tgagtgattg cgcatcccag gccgcacttg
    28621 ccagtagttt gctgtcgctg atcatcagat gatttccagt tttgcccgca gacatcccgc
    28681 actttgcatt gattgcaaaa tagacatcag atccatcggc gtagcgccca gcgcattgag
    28741 cgcgcgcacc acgttattga ggctggcgct ggaacgtacg ctttgcagcg aaccgccgct
    28801 ctggcgtaaa tcgatctgcg tttgtggagt aaccacagtc tgtccaccac caaacggtgt
    28861 atctggctgg ctgacattgg cctgacgatt gactgttact gagagatttc cctgcgctac
    28921 cgcgcagctg tcgagggtca cttcgcgatt catcaccacc gaaccggtgc gcgagttaat
    28981 cactacttta gcgtcctgcg gggtgacatt aacctgcata ttctggatat ctgcaaggaa
    29041 acggacctgg gaactgttgc cacttggtac gcgcacctga atagtccgcg catctaacgc
    29101 ggtggcgctg ccatatccac gcacgcggtt gatggtgtca gcgatttgct gcgccatgct
    29161 gaaatcttcg tcgttaagtt gcaaattaag ggtattcccg acgccaaact ggctgggcaa
    29221 ttcacgttca ataaccgcac cattggtgat ccgtccaccg ttcagttggt tcacctgaac
    29281 actgctaccg ccagcggagg ctcctgcgcc gccaaccaga atattgccct gcgccagcgc
    29341 atacacctga ctgtcaacgc ccttaagcgg cgtcatcaac aacgtacctc cacgcaagct
    29401 tttggcattt cccatggaag aaaccaccac atcgatggtt tgcccctgac gtccaaacgg
    29461 aggaagtgac gctgtcacca ttaccgcagc gacgtttttt agctgcatat tggtgcccgt
    29521 cggaacggta attcccagct gtgagagcat gttattaagc gtttgtgtgg taaacggcgt
    29581 ctgggttgtc tggtcaccgg tgccatccag ccccaccacc agaccatagc caatcagtga
    29641 gttttgcctt accccctgaa cactggtgag atcgcgaata cgctcagcct gagccgccgt
    29701 cgtaaccagt agaagaatta atgcagagag aaatttaatc accacagcct cacttacatt
    29761 ggcgacaggt taaggaagaa acgctgcaac cagcccatat tttgcgcttc gttaatgtag
    29821 ccattgccta cgtattcaat gcgcgcatcc gccacctgag tagacggtac ggtattgctg
    29881 ccgctgatag tgcgtggatt aaccacgcca gagaagcgaa taaattcggt accctgatta
    29941 atggcaatct gtttttcacc caccacatgc aggttgccgt tgaccagtac ctggtcaacc
    30001 gtcaccgtca acgtgccgct aaaggtattg ctggcattgg ccccgccctt tccgttgaac
    30061 gtgttaccac cggaggcttc gacatcggca cgagcgttac caaacagccc ctgcaaatag
    30121 cgcggcacag tatcaaagcc aaaattagtt ttaccgtcac ggctggcatt cgcagaggag
    30181 cttttgctgg cgctgacgtt ctcctgcaac acgatggtca gcgtatcgcc aatattgcgt
    30241 ggtcgacgat cttcaaacag cggttgatag ccatagttaa tcggctgagc agactggaaa
    30301 atagaaccgt tggcgacggg cgtcggaccg ggaaccggtt gtgcactggt cgccccctgc
    30361 accagcggcg tggagggtat ccaggcgcag ccggttagtg aaagcaccaa caagctggaa
    30421 atggcataag tatgcgcagc gtttttttgc atggctatca tcttcaaaaa tcagtaaacc
    30481 ggtgaacctg ccaccggtta agccttagag ttgcgtcagt ttttgcagca tctgatcggt
    30541 ggtggacacc gctttactgt tgatttcgta agcgcgttgc acctgaatca tattgaccag
    30601 ttcttccgcc acgttgacgt tagacgtttc aacataccct tgatacagca gtcccgcgcc
    30661 gttcaggccc ggcgtgcttt cgttcggtgc accagaggat tgcgtttcgg tgtagaggtt
    30721 ttcgccaatg ctctccagcc cggtgtcatt cataaaggtg gtgagattga gctgcccaac
    30781 ctgaaccgga gctgcctggc cttgttgggt tacgctgacc acgccatcac gaccgatggt
    30841 gatacttaac gcattcgccg gaatggtgat cgctggctgc acctgaaaac caccagccgt
    30901 caccagctgc ccgttctgat ccacctggaa agagccgtca cgggtatagg ctgatgaacc
    30961 atctggcaac atcacctgga aaaagccctg ccctttaatc gcgacatctt tgctgttgtt
    31021 ggtctgcgac aggtttccct ggctgtgtaa gcgttcagtg gcgaccgggc gtacccccgt
    31081 gccgatttgt aatccggagg gtaaggtggt ttgttcggaa gactgtgccc ccggctggcg
    31141 aatggtttga taaagcagat cttcaaacac cgcgcgctga cgcttaaaac cgttagtact
    31201 gacgtttgcc aggttgttgg caatgacgtc catattggtt tgctgggcgt caaggcccgt
    31261 tttggcgatc cataatgaac tgatcataaa atgtcctgta gtggattagt gacaagcaga
    31321 gcagaagcac gcgacagtgt gaatttcccc tcaccctaac cctctcccca aaggggcgag
    31381 ggaatagtcc gcgcgctttt attgcaatgt catcaatcgt tcaattaact catcgacagc
    31441 agttggttgg cacggcctgc gttatcatcg acgctgctga tcaccttcat ctgcatttca
    31501 aaacgccgcg cgctggcaat catgtcgctc attgccgcaa cggcattgac gttactgcct
    31561 tccagaaccc ccgacatcac acgcaaggtt ggatctgcct gcagtaccgg cccacgcgtg
    31621 gcctgggttt ctgcgcttaa acgaaaaatg ccgtcgtcac cgcgctgcac ttcgctgccc
    31681 gtggctttca ccagtttcag acgccccact ggcgcaaccg tatttgccgg atcgcccgga
    31741 ttgagcgccg agattgtgcc atcggcagca atagtgattt ccgccccttc cggcacagca
    31801 attggccccg cctcgcctat caccggatgc ccctgaattg tcagttgccc ggtgggatca
    31861 acctgaatgc tgccattacg cgtataccct tcgctgccgt cagcggtctg cacggccagc
    31921 cagccatcct gctgcaacgc aacgtccagc gggcgcgagg tgtaatccat cttgccgggc
    31981 gtcatgtctg cacccggtgt tgacgccgtt accagcgtgc gcgtaggcag tgaaagccct
    32041 tccaccggca ctgcacgcaa ggcgtttaac tgtgcgcgaa aaccgggcgt tgaggcattg
    32101 gccagattac tggcggttac cgcctgttga ttcagcgtct ggctggctgc tcccatcgcg
    32161 gtataaattg cgtgatccat tgagctatcc cgtcagcgat tagcgtaagt taaccagcgt
    32221 gttgaggatc tggtcctggg ttttgatggt ctgggcgtta gactgatagt tacgctgggc
    32281 aacgatcata ttgaccagtt ctttactgag atcgacgttg gacgcttcca acgcaccgtt
    32341 ggtcagggtg ccaaagttgc ccgtcccggc tgtccccaac agcgccacgc cagaagattg
    32401 cgtcgcagac cagacgttgt cgccttcgga tgccagacct tcgttgttgg caaagttcgc
    32461 cagtacaatc tgccccagca gttgtgtttg ttcgttggaa tagttgccga caaccgtacc
    32521 gtcatcattg atttgataac tcaccagatc gcccggtttg tagccattct gggtggttgc
    32581 cacaatattg ttagcgccgg tattttgctg catggagttg aggaagctca ggctaaacgt
    32641 ggcgggatct gcgccgttaa ttgcgccagt ggtaatattc tctgttggat ttgaggtcag
    32701 aacgccattg gcattaaaca ccagcttcat tgcaggctcg gctgtacctg ttggatcact
    32761 gctatcctgg gtgtagacct gccagttatt atccccggtc ttcacaaagt acacgctcat
    32821 gtcatgagca ttaccctgac tatcgaaaac agtcaccgaa ccttttttgt tatagctatc
    32881 cgcattgctg gcgctgaatg gcgtaacagt aggaagcgga tcactggaat tcaggttgat
    32941 ctgcatcgat gccgtggtgg tagttttcgc tgccatcagg gtattcggga tcgaaatatt
    33001 ggtcggattc gccccttgct gaatagtcgg cggcgtaccg gttgccgggt aacccgtcag
    33061 ctgtaaacct tgcatattca ccaggttacg gttttcatcc agcttaaatt gtccgttacg
    33121 gctgtagaac accgaaccgt tgctgtctac cagacggaaa aaaccgttct ggctgatagc
    33181 aacgtccaga cctcgcccgg tgttggtggt cgtgccatcg gtaaagtcct gagtgatacc
    33241 ggcaactttt acccccagtc ccactttcga accggcaaac atatcggcaa aagaggccgt
    33301 gcctgattta aagccgtagg tggcggagtt ggcgatattg ttgccaataa catcgaggtt
    33361 ggtggcggca gcgtttaatc cgctaaccgc ttgagaaaag gccatgactg actcctgaaa
    33421 tgtgaaggct taaattatct gccgtacttc gtcgagggtg gtggtgccgt aagtgccgag
    33481 atccagcgta ttaccgctgt tgccgcggat cacaccctgc accagagcaa actgcagcgg
    33541 ctgggcaacc agttgtgtac caccgttact ggcgctaatc gctacattgt aagaaccgtt
    33601 cggcgcagtg ctgccgtcag tcaacgtacc gtcccaggtg aaactgtgaa ctccggcggt
    33661 cagttcacca atatcaatgg tgcgcacaac cgcaccattt ttatcggtga tggtggccgt
    33721 aactttgtct gccgcctgtt gcagctcaac accaaacggc gtggtcgtgg tcacagctcc
    33781 ttcttcactg ccggttcccg caagaacagt ggtgccgggg atcatcacgc cgtgaccgat
    33841 caggttactg gcctgtaacg actggctgtt atcaatctgt ccggaaatag atccgagtgt
    33901 ggtattgagt ttttcaatcc cgctgaccgt gctgatttgt gccaattgcg acgtcagctc
    33961 gttgttttcc attggattgg tcgggtcctg gtttttcagc tgcgccacca gcaaagtcag
    34021 aaaactgctt tgtaaatctg cggcgttgct gcccgtgagc gaactactgc tggtggtact
    34081 gacgccggta tttgtcggat cggtggtggt taccgcaatg gacatagctt tctcctttat
    34141 tgaccgagcg taagggtttt cagcatcatg cttttcaccg tgttgagcac ttcaacgttg
    34201 gcctgatagc tgcgtgacgc cgacatggtg ttaaccatct ccccgacgac atcaacgttc
    34261 ggcattttta cgtagccctt tgcatctgcc agcggattac ccggttcata aaccagtttg
    34321 tccggggcct gactttctat aacatcggca acctttacgc cgcctgtcgc agcacctggt
    34381 gcagcgttaa cctggaatac cacctgtttt gcccgatatg gctgtccatc aggaccggtc
    34441 acgctatcag catttgccag attactggcc gccacgttca ggcgctggga ctgggcagtt
    34501 aacgccgacc cggcgatatc aaaaatattc agcagtgcca tccgttaatt tccgctctgt
    34561 aaaacgttca tcatgccttt gatttgcccg ctcaacgcgc taaggctcat ctggtattgc
    34621 aggctgttat cggcaaactg ggtgcgttcg cgatccatat cgacggtatt accgtcaagc
    34681 gaaggctggt ccggaatacg gtattgcagt tctgcggtag gaggcgtcag cgcctgcgcc
    34741 gggatgtgtt gcgttgaggt catcgtcagt gcaaccacac tggttgcatc ccgtccacgt
    34801 tgcatgactt ttttaagttc actggcaaaa tcgatatcgc gcgcctgata accaggggta
    34861 tcggcattgg cgatgtttgc tgccagcact tcctgacgct gggcgcgcag attgagcgcc
    34921 tcttgttgaa aacgtaaggc ggcgtcgagc ttatcgagca tatctcctcc gcaggtatca
    34981 aaattctgcc atcagcttaa atgcctttac gcgcgcgtta tcggcggaat aaacgcaaaa
    35041 tgggtcgcta tttatgccgt tgatggtcat tgcggacagg tacaattcac gttgtagaaa
    35101 tggctggggg cgaaaatgct gacaataaaa cgtagcgtgg cgatcatcgc gatactgttc
    35161 agtccgttaa gtacggcgag caatctcaca tcgcaattgc acaacttttt tagcgcccag
    35221 ctcgcggggg taagtgatga ggttcgtgtt tctattcgta cagcgcccaa tctactaccg
    35281 ccgtgcgagc agccattgct ttcgatgagc aataattccc gcctgtgggg caatgtgaat
    35341 gtgttggcac gctgcggtaa cgacaaacga tatttacagg ttaatgtaca ggccacagga
    35401 aattatgtgg ttgccgcgat gcccattgcg cggggaggaa agctggaagc tggcaatgtc
    35461 aaactgaaac gcggacggct ggataccctg ccaccgcgta cggtgctgga tatcaatcaa
    35521 cttgttgatg ccattagcct gcgcgatcta tcacccgatc aaccaatcca gttaacccag
    35581 tttcgccagg catggcgggt aaaagcggga caacgcgtca atgtgatcgc cagcggtgat
    35641 gggtttagcg ccaacgcaga aggtcaggcg ctgaacaatg cagccgtcgc acagaatgcg
    35701 cgggtgcgca tggtatcggg acaggtagtc agcggcgttg ttgatgcaga tgggaatatt
    35761 cttataaacc tgtaagctgt taaagattac ccgtcccttg ccgataaata agcaacacat
    35821 gataaaagcg ccctcaatga ggaataaacc atgagtattg atcgcacttc gcctctgaag
    35881 cctgtaagca ccgttcaacc gcgcgaaacc actgacgcgc cggtaacgaa cacccgggcg
    35941 gcaaaaacaa cagcctccac cagcaccagt gtgacgttaa gcgacgcgca agcaaaactg
    36001 atgcaacccg gcagcagtga tatcaatctt gaacgtgtcg aagcgttaaa actggcgatt
    36061 cgtaacggtg aactaaaaat ggacaccggc aaaattgccg atgcgctgat caacgaagcg
    36121 cagcaagact tgcagagtaa ctgatcgtat gacacgtctt gcagagatcc tcgaccagat
    36181 gtccgctgtg cttaacgatc tcaaaacggt aatggatcaa gaacagcaac atctctctat
    36241 ggggcagatc aacggcagcc agttgcaatg gattacagaa caaaaaagct cactgctggc
    36301 gacgctggat tacctcgaac agttacgcaa gaaagaaccc aatacagcaa atagcgttga
    36361 tattagtcaa cgctggcagg aaattactgt gaaaacgcag caactacgcc aaatgaatca
    36421 acataacggc tggttactgg aaggacagat tgagcgcaat caacaggcgc tggaaatgtt
    36481 gaaaccgcat caggaaccga cgctatatgg ggcgaacggt cagacctcaa caacccatcg
    36541 cggcggtaaa aagatttcga tctgaatatt atctccggcc tgcactgcag gccggaatgc
    36601 attgttacac cgtccggcgg gcaaattctt taactttgaa gcccagtacc gccagtgcag
    36661 cgaagtacgc ggcaatcccc gccagcacga ccgccattaa acgcagtaag cgccagggca
    36721 tggtacccaa tgaccactcc ggcatgatat gtaacatacc taaaagcacg ccagacatca
    36781 ccagtaccgc caccaccaga cgcaacagaa acgccatcca gccgggttgc ggggtaaaga
    36841 ttttctgctt acgcaactgc cagtaaagca gcgaagcatt cagacacgcc gccagaccaa
    36901 tagaaagtga cagcccggca tgtttcaacg gaccaataaa cgccaggttc atcaattgcg
    36961 ttaaaatcag cgtaacgatg gcaattttca ctggcgtttt aatgtcctgg cgggaataaa
    37021 agccaggagc caaaactttc actacaatca ggccaatcaa acccaccgag taggcaatta
    37081 acgcccgctg ggtcatcagc gcatcaaagg cggtaaattt accgtactgg aacagcgaaa
    37141 cggtcaacgg acctgaaaga atgcccaacg caaccgcact cggcagcgcc aacaggaaac
    37201 aaagacgcag cccccagtcc atcaaacggt tgtattcatc atgattgcca ctggcaaaac
    37261 tcttcgacag cgacggcagc aaaatggtgc caagcgccac gcccagcaca ccagacggaa
    37321 actccattaa gcggtcggcg taatacatcc aagacaccga accggaagca agaaacgagg
    37381 caaaaatggt gttgatgatt aaggagatct ggctcacaga gacgccaagg atcgccggtc
    37441 ccatctgttt caccacgcgc attgctccgg catcgtggaa gttaatgcgc ggcaggacca
    37501 gcatgccgat cttcttcagg tgcggtagct gatacaccag ctgcaggatg ccgccgaccg
    37561 taacagccca cgccagcgcc agcaccggtg ggttaaagta cggtgcggca aacagcgcga
    37621 aaccaatcat gctgatgtta agcagtgttg gcgcaaacgc cggaatcgag aagcggttcc
    37681 acgtattcag aatcgctccc accagcgacg ccagggagat cagcaagata tagggaaagg
    37741 taatctttag tagctggctg gtcagggcaa atttgtcagc tgtgtcagcg aagcctggcg
    37801 cggtcaccat gatcacccac ggtgcggcga gcatgccagc gaccgtcaca accgccagcg
    37861 caagtgtcag caggccagaa acataagaga caaagacccg cgtggcgtct tcaccctgct
    37921 tacttttata ttccgccaga atcggtacaa atgcctggga aaatgcccct tcggcaaaga
    37981 tacggcgtaa caagttagga agtttaaaag cgacgaaaaa ggcgtcggtt gccatccctg
    38041 cgccaaagat tctggcgaca attgcgtctc gtgcgaagcc aagcacacgc gaaaacatgg
    38101 tcatcgagct gacggcggcc agcgatttta ataaattcat cggtgttcta atccagaccc
    38161 acgggcaaaa cgcctgcaag gcaggcgctg aaagaggcga atagtctacc tggattatgg
    38221 tgaattgcta ccgccagatg ttacagggtt tattcactca tcgcatcgcg ccagatcttg
    38281 tcaacgatac gttgcgccag cacggcctgt tcgccggcgg tttgcggaac tgtctgattt
    38341 tgcacacatt caatgaagtg ccgcgcacag ccgacaaatc cacgttgttc aagagtgctc
    38401 tgccaaccag gaatcggttt atgcactacg ccctgcccgc gctcctcacg ccattcgcgc
    38461 atatccgtaa tgtcgatgag cgcaccgtca gtcacggcct gcacggtttc acgctgactt
    38521 ccggcacggc gatgcataca ggtggtgatc tgcaaaggac cggccgaaaa atggtgctcg
    38581 gcaaacagca tttcgccagc gtcgttagtc agtagcgtac cgccatccag agaggctttg
    38641 ccgcccgaca accacagcgc ggtatccacc acatgcagat aatcatccag caacgtgaaa
    38701 taaagatcgt gtggcccgac actattgcta cgatgtttat ccattcttag cgaagctgcg
    38761 gtagcgagtt gcgtttttaa ctcaccgtag agtggtgcga aacgacggtt aaaaccgacc
    38821 atcaacgtca gttttttacg cgccgccagt tccaccagcc gttcagcatc gcgcagattt
    38881 tctgccagcg gtttatcgac acagacatgt acacccgcat tgagtaacgt actgaccacg
    38941 tcaaagtggc tggcggtgct ggaatgcaca aaaaccgcat cgcaactggc ggcaaggctg
    39001 gataacgaat cggcataagg aatgcgccag ctttcacaaa ttggcagggc tttcgcgcgc
    39061 gtaggcgacc aggctccttg taacatccag tcagacgctg ccgccagcac cggtaaccac
    39121 gctttttgcg caatgccgcc taatcccaca acgccgatac gtaatttttt cactttaatc
    39181 tcccagatgg gccagcaacg aatcaagacg ctgtttcagt tctgccactt cgatttccag
    39241 ggcttcgacg cgggcctgta aatcaccatc aaccgcgttc gacatatccg ttaccgccgg
    39301 ctgatcctct acctcaccac tgaaaagatg catgtagcgg ctttcgcgtt tacccggttc
    39361 gcgggccaga cgcaccacaa aaggaccatc ttcgcgattt gccagttgtt ccagcgtcga
    39421 ctccacttcc gccatatcgc tgaattcata cattcgcgcg gcgcggctgc gcagttcacc
    39481 tggcgtctgg gcaccacgca ataacaacgt ggtgattaac gccacttccg ctgcgctcag
    39541 tttcagatcg ccaaattctg aattacaaaa acgttgctca tatttggtga cccgattacc
    39601 aaaaccgctc actgtgcgta gataatgacg tttgaccaga ttatccagct gttcctgcac
    39661 ttcggattca ctcagattca tgaccggttc acggttcgtt ttctgattac aggccgtgac
    39721 tacaccattg actgagagcg ggtattgctc cggcgtggtc acctgctttt ccagcaagca
    39781 accaatcacg cgagcttcaa gggcagtaag ttgatatttc atgagattct ccttagcggc
    39841 cgggcgtcca gtctggggta gttaatgccg tcagtacgtg atcgcgccat tgtccatcaa
    39901 tcaacagata gtctttcgca tagccttctt tttcaaaacc cagtcgcgcc agtaaatcac
    39961 cgctgcgttt attgtgcggc atataattag ccataatgcg atgaatatgt tgggtgcgct
    40021 gcatataacg aatggctgcg gtcagggctt caaacatgag tcctttgccc tgccattttt
    40081 gcccaatcga ataaccgaga tagcaggcat gaaaagagcc acgaacaaca ttggaaaaat
    40141 tggcaacgcc aataatctct ttttcgtccg ggtcgaataa gccaaagtag aaagctgaac
    40201 cttgtttatg aaattcgtta atcatcccca gcctggcctg ccagcctgat ggataacagt
    40261 ggctttcgtc gcgcactggc tcccagggct tgaggaaatg gcgattctct gcgtaataat
    40321 ccgcaagacg ccaggcatca cgatcatgca ccagacgcac gaccagtcgg tctgtggtta
    40381 agcgcacttt tggcacgtta ctgcgatagc caaacattct atacctactc cttcccgtaa
    40441 cgtctttaat acgctgtaag tattactata cctgcgcaac cagaccctgt gaaaagtcca
    40501 aaatgccatt ttctgcatta ttcacatatt tgataaaaac tctctatcaa agcgacgttt
    40561 tgataaaaaa atattgtccc ctaagtgatg ggaaaagtct tagcggcaat gcagaataga
    40621 aagtgctcat cttttatttc ccgggagggg aaatgtcccg cgtatcgcag gcgaggaacc
    40681 tgggtaaata tttcctgctc atcgataata tgctggtcgt gctggggttc tttgttgtct
    40741 tcccgctgat ctctatccgc ttcgttgatc aaatgggctg ggccgccgtc atggtcggta
    40801 ttgctctcgg tctacgccag tttattcagc aaggtctggg tattttcggc ggcgcaattg
    40861 ccgaccgctt tggtgccaaa ccgatgattg ttaccggtat gctgatgcgc gccgccggat
    40921 tcgccacaat gggtatcgcc cacgaaccgt ggctattgtg gttttcatgc ctgctctcgg
    40981 gactcggcgg cacgttgttt gatccgccgc gttcggcgct ggtggtgaaa ctaatccgtc
    41041 cacaacaacg tggtcgtttt ttctcgctgt tgatgatgca ggacagtgcc ggtgcggtca
    41101 ttggcgcatt gttggggagc tggctgttgc aatacgactt tcgcctggtc tgcgccacag
    41161 gggccgtttt gtttgtgctg tgtgcggcgt tcaatgcgtg gttgttaccg gcatggaaac
    41221 tctccaccgt acgcacgccc gttcgcgaag gcatgacccg cgtgatgcgt gacaagcgtt
    41281 ttgtcaccta tgtcctgacg ctggcgggtt actacatgct ggctgtacaa gtgatgctga
    41341 tgctgccaat tatggtcaac gacgtggctg gcgcaccctc tgccgttaaa tggatgtatg
    41401 ccattgaagc gtgtctgtcg ttaacgttgc tctaccctat cgcccgctgg agtgaaaagc
    41461 attttcgtct ggaacaccgg ttgatggctg ggctgttgat aatgtcatta agcatgatgc
    41521 cggtgggcat ggtcagcggc ctgcaacaac ttttcaccct gatttgtctg ttttatatcg
    41581 ggtcgatcat tgccgagcct gcgcgtgaaa ccttaagtgc ttcgctggcg gacgcaagag
    41641 ctcgcggcag ctatatgggg tttagccgtc tgggtctggc gattggcggc gctattggtt
    41701 atatcggtgg tggctggctg tttgacctgg gcaaatcggc gcaccagcca gagcttccgt
    41761 ggatgatgct gggaattatt ggcatcttca ctttccttgc gctgggttgg cagtttagtc
    41821 agaaacgtgc cgcgcgtcgt ttgctggaac gcgacgcctg atttgatact cccccctgac
    41881 tcctccatac tgaaagtgaa ctgacagcca aatggaggag tcacgtgaag ctatacattt
    41941 acgatcactg cccttactgc ctcaaagccc gcatgatttt cggcctgaaa aatatccccg
    42001 tcgaattaca tgttctgctc aacgacgacg cagaaacacc cacccggatg gtcggtcaaa
    42061 aacaggttcc cattctgcaa aaagatgaca gccgctatat gccagaaagc atggatatcg
    42121 ttcactatgt cgataaactc gacggcaaac cgttactgac cggcaaacgt tcccctgcca
    42181 ttgaagagtg gctgcgcaag gtcaatggct acgcaaacaa actgctgttg ccgcgttttg
    42241 ccaaatcggc attcgatgag ttttctactc ccgccgcgcg caaatatttc gtcgacaaga
    42301 aagaggccag cgcgggtaat tttgccgacc tgctggccca ctctgacggt ctgattaaga
    42361 atatcagcga tgatttacgt gcgctggaca aactgatcgt caaaccgaac gccgtgaatg
    42421 gcgaactttc ggaagatgat attcagctat ttccgctgct gcgtaatctg acgctggtag
    42481 ccggaatcaa ctggccaagc cgcgttgctg attaccgcga taatatggcg aaacagacac
    42541 aaatcaattt gttatcatca atggcgattt aatcctgacc cgccgcggca gcctgtattc
    42601 gcgggttgcc gccgttttca gttttttctg ctggcgagtt tatcgctggt gacacatgct
    42661 gcgttgtgtc aggatattga cgcagatttc atgtcgagga ctaccatgaa caagttttta
    42721 tttgccgctg cattgatcgt cagtggcctg ctcgttggct gtaatcaact cacccaatac
    42781 accatcaccg aacaagaaat taaccagtcg cttgcgaaac ataataattt ctcaaaagat
    42841 atcggtttac ccggcgtggc tgacgcccat attgttctga caaacttgac cagccaaatt
    42901 ggtcgcgaag agccgaataa ggttacccta accggagacg ccaatctgga catgaactcc
    42961 ctgttcggta gtcagaaagc gaccatgaaa ctgaagctga aagcgctgcc cgtgtttgat
    43021 aaagaaaaag gtgcgatctt cctgaaagag atggaagtgg tcgatgcgac ggtacaaccg
    43081 gaaaaaatgc aaacggtgat gcaaacgttg cttccctatt tgaaccaggc attacgcaat
    43141 tactttaacc agcaacctgc ttacgtcctg cgcgaagatg gcagtcaggg cgaagcaatg
    43201 gcgaaaaaac tggcgaaagg cattgaagtg aagccaggcg aaattgtcat tccgtttacg
    43261 gattaatgac gagggcgcat tcgcgccctt tatttttcgt gcaaaggaaa acgtttccgc
    43321 ttatcctttg tgtccggcaa aaacatccct tcagccggag catagagatt aatgactgca
    43381 ccatcccagg tattaaagat ccgccgccca gacgactggc accttcacct ccgcgatggc
    43441 gacatgttaa aaactgtcgt gccgtatacc agcgaaattt atggacgggc tattgtaatg
    43501 cccaatctgg ctccgcccgt gaccactgtt gaggctgccg tggcgtatcg ccagcgtatt
    43561 cttgatgccg tacctgccgg gcacgatttc accccattga tgacctgtta tttaacagat
    43621 tcgctggatc ctaatgagct ggagcgcgga tttaatgaag gcgtgttcac cgctgcaaaa
    43681 ctttacccgg caaacgcaac cactaactcc agccacggcg tgacgtcaat tgacgcaatc
    43741 atgccggtac ttgagcgcat ggaaaaaatc ggtatgccgc tactggtgca tggtgaagtg
    43801 acacatgcag atatcgacat ttttgatcgt gaagcgcgct ttatagaaag cgtgatggaa
    43861 cctctgcgcc agcgcctgac tgcgctgaaa gtcgtttttg agcacatcac caccaaagat
    43921 gctgccgact atgtccgtga cggaaatgaa cggctggctg ccaccatcac tccgcagcat
    43981 ctgatgttta accgcaacca tatgctggtt ggtggcgtgc gtccgcacct gtattgttta
    44041 cccatcctca aacgcaatat tcaccaacag gcattgcgtg aactggtcgc cagcggtttt
    44101 aatcgagtat tcctcggtac ggattctgcg ccacatgcac gtcatcgcaa agagagcagt
    44161 tgcggctgcg cgggctgctt caacgcccca accgcgctgg gcagttacgc taccgtcttt
    44221 gaagagatga atgctctgca gcactttgaa gcattctgtt ctgtaaacgg cccgcagttc
    44281 tatgggttgc cggtcaacga cacattcatc gaactggtac gtgaagagca acaggttgct
    44341 gaaagcatcg cactgactga tgacaccctg gtgccattcc tcgccgggga aacggtacgc
    44401 tggtccgtta aacaataaaa atcgtagctt cctgttgtca ttaggttatt ttaactgtat
    44461 aaataaccag tatattcaac agggggctat tatgcgaatt gaagtcacca tagcgaaaac
    44521 ttctccattg ccagctgggg ctattgacgc cctggctggc gaactttccc gccgtattca
    44581 gtatgcgttt cctgataatg aaggccacgt atcggtacgt tatgccgcag cgaataattt
    44641 atcggttatt ggcgcaacaa aagaagataa acagcgcatt agcgaaattc tccaggaaac
    44701 gtgggaaagc gccgatgact ggtttgtcag cgaataatat gcagtgattt ttgtttttgc
    44761 cgggtcgccc cggctttttt attttactta caaattttga gtacaaaatt tctacacttc
    44821 ctcaaaataa ttgcacaata tgctaaaaaa atatgaatga catgctgttt tattgttcat
    44881 ataaatctta aaagcagaaa tttatctgtt ccccccttta aaaattcggt gaataccctt
    44941 acttattggt atactgaagt tgcttcagat aaaaacgcat tgaacctcga ataacgttgt
    45001 ctagtaacac gaattagggg gccatgatgg aaaaaaataa tgaagtcatt cagactcatc
    45061 cgctcgtagg gtgggacatc agcaccgttg atagctatga tgcgctgatg ttgcgtttgc
    45121 actaccagac cccaaataag tccgagcagg aagggactga agttggtcag acgctctggt
    45181 taaccactga tgttgccaga caatttattt cgatattaga agcaggaatc gccaaaattg
    45241 aatccggtga tttcccggta aacgagtatc ggcgtcatta acatgacatg accatccacc
    45301 caaaaggcac ctcaccggtg cctttaccat ttctgggttg tatatctgca ttcagttaat
    45361 tactctgctt aaaccatgag agcagagaga aaaaaatgaa atacgatctc atcattattg
    45421 gcagcggttc cgtaggcgct gccgccgggt attatgcaac ccgcgccggt ttaaacgtgc
    45481 taatgaccga cgcccatatg ccaccgcatc aacacggcag ccaccacggc gatacgcgat
    45541 taattcgcca tgcttatggt gaaggcgaaa agtatgtccc gttggtcctc cgcgcgcaaa
    45601 cgctgtggga tgaactttcc cgccacaacg aagatgatcc catttttgta cgctctggtg
    45661 tcattaacct cggcccggct gactccgcat ttctcgccaa cgtcgcccac agcgccgaac
    45721 agtggcaact caacgttgaa aagctcgatg cgcaagggat tatggcccgc tggccagaaa
    45781 tacgcgtccc ggacaactac atcggcttat ttgagactga ttccggtttt ttgcgcagcg
    45841 aactggcgat taaaacctgg atccaactgg cgaaggaagc gggctgtgcg caactgttca
    45901 actgcccggt caccgcaatt cgtcatgacg atgatggcgt aactattgaa accgttgacg
    45961 gtgagtatca ggcgaaaaaa gcgattgtct gcgcgggaac atgggtaaaa gacctgctcc
    46021 cggagctgcc tgtccagccc gtacgcaaag tatttgcctg gtatcaggcc gatgggcgct
    46081 atagcgtgaa gaataaattc ccggcgttta ccggtgaact tcccaatggc gatcaatatt
    46141 atggttttcc ggcagaaaac gacgcgttga agattggcaa acataacgga ggccaggtta
    46201 tccattcagc ggatgaacgt gttccgtttg cggaagtggt cagcgatggt tcggaagcct
    46261 tcccgttctt gcgcaatgta ttgccgggta tcggttgctg cctgtacggc gctgcctgca
    46321 cctatgataa ttcgcctgac gaagatttta ttatcgatac cctacccgac cacgataata
    46381 cactgttcat taccggcctg agtgggcacg gttttaaatt tgcgtcagtt ttaggggaaa
    46441 tagctgccga ttttgcgcaa gacaaaaaaa gcgattttga tttaacgcca ttcaggcttt
    46501 cccgcttcca ataatcatca ttacggcctc cagaatgagg ccgtttttac aggagtattt
    46561 aatgcgtcgg ctgttgcact atctcatcaa taatattcgc gagcatctga tgctttatct
    46621 ttttctctgg ggattgttgg caattatgga tctgatctat gtgttttatt tttagttttc
    46681 cgcactgaca taaactgaca aatatttaat cttcctttca tttagcgtga aaaattgaat
    46741 gagattattc ctgcttctac agcactcacc agacatctct gatgctgaac ccactaatct
    46801 tatgaagatt ctttcattat taattcaaaa ttattgaaat aaaaataaat atcattcaat
    46861 ttggtatttt tgtgttgcaa ttcattctcc gacacgccat tttctttctc tcgcaaattc
    46921 gttttggatg cacttatgtc attcacaaat acccctgaac gctatggtgt tatatctgcg
    46981 gccttccatt ggctaagcgc aattattgtc tacggcatgt ttgctttagg tctgtggatg
    47041 gtcacgctca gttattacga tggctggtat cacaaagcac ccgaactgca taaaagcatc
    47101 ggtattttgt taatgatggg gctggttatt cgcgttctgt ggcgtgtcat atctccaccg
    47161 ccgggtccgc tgccgagtta ttcgcccatg actcgtcttg ccgcaaaagc tggacatctc
    47221 gcattgtacc tattgctgtt cgccatcggc atcagcggct atctgatctc aactgccgat
    47281 ggtaaaccga tcagcgtttt tggctggttt gacgtccccg cgacccttgc cgacgctggc
    47341 gcacaggcag actttgccgg tgccctgcat ttttggctcg cgtggagcgt cgtagtactg
    47401 tccgttatgc acggatttat ggccctgaag catcatttca tcgataaaga cgacactctg
    47461 aagcgcatgc tgggaaagtc gtcatctgac tatggagtat aaaaaatgaa aaaaagcctg
    47521 cttggtttaa ccttcgcgtc cctgatgttc tctgccggtt cagcggttgc cgccgattac
    47581 aaaattgaca aagaaggtca gcacgccttt gttaatttcc gcatccagca ccttggctat
    47641 agctggttat acggcacctt taaagatttc gacggtactt ttacctttga cgaaaaaaat
    47701 ccggctgccg ataaagtgaa tgtgacaatt aacaccacca gcgtcgatac taatcacgcc
    47761 gaacgcgata aacatcttcg cagtgcagat ttcctcaata ccgcaaaata tccacaggca
    47821 acattcacct ccaccagcgt gaagaaagac ggtgacgaac tggatattac cggcgatctg
    47881 acgctgaatg gcgtaaccaa acccgtcacg ctggaagcga aattaattgg tcagggcgac
    47941 gacccatggg gtggtaaacg tgcaggcttc gaggccgaag gcaaaattaa gctcaaggac
    48001 ttcaatatca agacagattt aggtccagct tctcaggaag tggatctgat tatttcagtg
    48061 gaaggcgtac agcagaagta agagtgaaat gttgccggat ggcacgcatc cggcaatgat
    48121 atttattccg ttggatcagg aatgcccagt gttgtattca gacgtccacg agacttatta
    48181 aagatcttat tgccattttc acgtcctgcc cgacggcgtc gctgttcttc tggcggtaac
    48241 gcgctttctt cgcagcaaat ctcactacaa caacctttgt atttttccgc acatactgga
    48301 cactgaataa acagcaggtg gcagccatca tttttacagt tggtatggct gtcgcacggc
    48361 gcgccgcact ggtggcaatg cgcgataatc tcatccgata tacgttcgcc catccgctcg
    48421 tcaaaaacaa aatttttgcc aataaaacgc accggcaagc cctgctcgcg cgccttacgg
    48481 gcgtattcaa taattccgcc ctcgatatgc cagactttgt tgaatccgtt atgtttcatc
    48541 caggcactgg ccttttcaca acgaatgccg ccggtgcagt acatgacgat ttttttatct
    48601 ttatgtgcct gcatcatctc gactgctttt ggcagctgct cacggaaggt atctgccgga
    48661 atttcgagcg cgttttcaaa gtgccccact tcatactcat agtggttacg catgtcgata
    48721 aatagtgcat cgggatcgtc aagcatggcg ttcacttccg ccgcttgcag atactcacca
    48781 acattgctgg catcaaagtg aggatcgtca ataccgtcgg caacaatgcg atcgcgtacc
    48841 ttcatgcgca gtacccagaa ggatttcccg tcatcatcca acgcgatatt caggcgtaaa
    48901 ccctctaaag ccgggtcgaa ggcatagagc tgcgcgcgaa atgtttcaac attgctcgca
    48961 ggtacgctga tttgcgcgtt aatgccctca tgcgccagat acactcgccc aaaaacattc
    49021 agcgcggtaa acagctgata taaagcgtca cgggtcgcct taggatcggc gatgtggaaa
    49081 tacttgtaaa acgaaatggt ggttcgcggt tcgctctcag ccaacatttt ggcttttagc
    49141 gcgtcgttgg aaatgcggtt gtgtaacact ggcatggtgt acggttcctg cgagatggga
    49201 aagtaaaaat ccgcggcatg atatagcaat tatcgataat taacatccac acattttacg
    49261 ctacatttgc gcattaaaaa ttatttgtta tttacaagcg cggcaatttc gcccagtctt
    49321 cagccacaaa ttttggttgc gggcgaaaaa atgcgacaat acatacaatt gcccgaatag
    49381 gttgaaaaac aggattgata tgacgaatct acccaagttc tccaccgcac tgcttcatcc
    49441 gcgttattgg ttaacctggt tgggtattgg cgtactttgg ttagtcgtgc aattgcccta
    49501 cccggttatc taccgcctcg gttgtggatt aggaaaactg gcgttacgtt ttatgaaacg
    49561 acgcgcaaaa attgtgcatc gcaacctgga actgtgcttc ccggaaatga gcgaacaaga
    49621 acgccgtaaa atggtggtga agaatttcga atccgttggc atgggcctga tggaaaccgg
    49681 catggcgtgg ttctggccgg accgccgaat cgcccgctgg acggaagtga tcggcatgga
    49741 acacattcgt gacgtgcagg cgcaaaaacg cggcatcctg ttagttggca tccattttct
    49801 gacactggag ctgggtgcgc ggcagtttgg tatgcaggaa ccggggattg gcgtttaccg
    49861 cccgaacgat aatccactga ttgactggct acaaacctgg ggccgtttgc gctcaaataa
    49921 atcgatgctc gaccgcaaag atttaaaagg catgattaaa gccctgaaaa aaggcgaagt
    49981 ggtctggtac gcaccggatc atgattacgg cccgcgctca agcgttttcg tcccgttatt
    50041 tgccgttgag caggctgcga ccacgaccgg aacctggatg ctggcacgga tgtccggcgc
    50101 atgtctggtg cccttcgttc cacgccgtaa gccagatggc aaagggtatc aattgattat
    50161 gctgccgcca gagtgttctc cgccactgga tgatgccgaa actaccgccg cgtggatgaa
    50221 caaagtggtc gaaaaatgca tcatgatggc accagagcag tatatgtggt tacaccgtcg
    50281 ctttaaaaca cgcccggaag gcgttccttc acgctattaa atctcccatg ccggatgctt
    50341 cagaatggca tccggcatta ccacagcaaa tccccctgat ttagcgataa aagctctctg
    50401 gattgcgccc cctggaagtc gggcgcataa ttagtgtgct tatcttttct tcttatgttc
    50461 accgcgcctg gcgcaccaac agcggattgc tatgtcaccc tgtgaaaatg acacccctat
    50521 aaactggaaa cgaaacctga tcgtcgcctg gctaggctgt tttcttaccg gtgccgcctt
    50581 cagtctggta atgcccttct tacccctcta cgttgagcag cttggcgtta ccggtcactc
    50641 cgccctgaat atgtggtccg gtattgtctt cagcattaca tttttatttt cggccatcgc
    50701 ctcaccgttt tggggtggac tcgccgaccg taaaggccga aaactcatgc tattacgctc
    50761 tgccctcggc atgggcatcg tgatggtgtt gatgggactg gcacaaaata tctggcagtt
    50821 tttgatccta cgggcgcttc ttgggttact tggcggattt gtccccaacg ctaatgctct
    50881 tatcgccaca caagtaccgc gtaataaaag cggctgggcg ctgggtacgc tctccacagg
    50941 cggcgttagt ggtgcgttgc tcggcccaat ggctggcggc ctgctcgccg atagctacgg
    51001 cttacgtccg gtattcttta ttaccgccag tgtgctcata ctctgctttt tcgtcaccct
    51061 gttctgcatc agagaaaaat tccagccggt cagcaaaaaa gagatgctgc acatgcggga
    51121 agtggtgaca tcacttaaaa acccgaaact ggtactcagc ctgtttgtca ccacgttaat
    51181 catccaggta gcgacaggct caattgcccc cattctgacg ctgtatgtcc gcgaactggc
    51241 gggtaacgtc agtaacgtcg cctttatcag tggcatgatc gcctcggtgc caggcgtggc
    51301 ggctctgcta agcgcaccac gactcggcaa acttggcgat cgaatcggac ccgaaaagat
    51361 cctgattaca gcgctgatct tttctgtact gctgttgatc ccaatgtctt acgttcagac
    51421 gccattgcaa cttgggattt tacgtttttt gctcggtgcc gccgatggtg cactactccc
    51481 cgccgtacag acactgttgg tttacaactc gagcaaccag atcgccgggc gtatcttcag
    51541 ctataaccaa tcgtttcgtg atattggcaa cgttaccgga ccattgatgg gagcagcgat
    51601 ttcagcgaac tacggtttca gagcggtatt tctcgtcacc gctggcgtag tgttattcaa
    51661 cgcagtctat tcatggaaca gtctacgtcg tcgtcgaata ccccaggtat cgaactgatt
    51721 tttcgccttt catacttgca aaagcggaga atcagctatc cttttccctg aaacctcatc
    51781 aactcaaagg gagaatcgtg atgaccatgt acgcaacgct tgaagaagcc attgacgctg
    51841 cacgcgaaga atttcttgca gacaaccccg gcatcgacgc cgaagatgcg aatgtgcaac
    51901 agttcaatgc ccaaaaatac gttttgcagg acggcgacat catgtggcaa gttgagtttt
    51961 ttgccgacga aggggaagaa ggtgaatgtt tacctatgct tagcggtgaa gccgcgcaaa
    52021 gtgtttttga tggcgactat gatgagatag agatacgcca ggagtggcag gaagagaata
    52081 cattacatga atgggacgag ggggaatttc agcttgagcc accgctggat accgaggaag
    52141 gacgcgcagc agctgatgag tgggatgaac gttaatcact catacgggcc atgatgagtg
    52201 tcgatcggca gcagtaaagt atcaaaaacc agagagaatg gcagatcaag gatcgtgaca
    52261 taacgccagg cggagtcacg cacatcccat tgcacaccgg gataatattg gttgccatgc
    52321 ccctgccccg gtatagtgcg actaataatg ctgccacagc cactcagcaa ggtcaccatg
    52381 atgctcacca caattaaacg catttgatac ctctttcgta aaaaaatacc ggcataacgc
    52441 cggtattttt attggctcgt tgtttttgcc ggatgcggcg tgaacgcctt atccgaccca
    52501 caaaatcttg caaaatcaat aaattgcagg aacgatgtag gcctgataag cgtagcgcat
    52561 caggcaacta cgtttttatt gcgaagccgc atccggttta cgcaatgcca gtggattgag
    52621 ctttatccct tcgtaataac tcacccatga agaatatctc tccggggaat tccagacgcg
    52681 gaaatgcaga cgggccatcg tcaccggatc gcttagcagc accaggcgac gatcgcgatt
    52741 cagcttctct ggcgtctcgt tcagcgcctg ttcaacgtgg cggtcacggg cgatttccag
    52801 caccttactg gcgcggtgac gcgcggtcgc cattgcggtt gccagagcgt taaatgacgg
    52861 gttaaacact gcgtgcataa agccatcatc aagggagcgt tgacgattca tctcaaggaa
    52921 ccgatcggta tcaaccagca cctgcggcgg cgaatactct tccgggatca ggaacagttt
    52981 ccagcgtttg gtgcgcagac caacggtggc acggctggaa atcaccgaaa caaacggtga
    53041 caggatcaac gagaagacaa tcggtgccag ccagaacagg aaacgcagat ccaaccacgc
    53101 cataccaaca gcccacacta accctaacag cagctgtgag ccgtggcgtt tgaacgcttc
    53161 accccaggaa gtggagtcat catcacgctg cggtgaattc cacaccactt cccagccaag
    53221 gaacgcgctg acaacgaaga ccgtatggaa cagcatgcgt accggagcca gcagcacgga
    53281 aaaaagcact tccagcagca acgataatgt aacgcgccag aagccgccgt attctttcgt
    53341 tcctttgcac cagataagca aaatgctcaa taacttcggc aggaacaaca gcaccatagt
    53401 cgaagcaaaa agtgcaatcg ccagctcagg acgccactgc ggccacaccg ggaacaactg
    53461 ccgtggttgc aggaagtatt gcggttcggt caacgcatgt actacctgca atgcagtaga
    53521 gagcgcgagg aacataaacc acagcggagc ggagagataa gacatcacgc ccgtcaggaa
    53581 taccgcacgg tgaaccgggt gcataccctt caccaggaac agacggaagt tcatcaggtt
    53641 accgtggcac cagcggcggt cacgttttag ctcatcaagc aagttaggcg gcaattcttc
    53701 ataagaaccc gggagatcgt aagcaatcca gaccccccaa cctgcacggc gcatcaacgc
    53761 cgcttccacg aagtcatgtg acaggattga accggcaaag gaaccttcgc ccggcagcgg
    53821 agccagtgcg cagtgctcga taaacggttt cacgcggata atcgcgttat gtccccagta
    53881 gtgcgactcg ccaagttgcc agaagtgcaa accggctgta aacagtggcc catacacgcg
    53941 ggtcgcgaac tgctgacagc gcgcatacag cgtatccata ccggacgctt tcggcgacga
    54001 ctgaatgatc ccggcgttcg ggttggcttc catcaggcgc accaggccgc ataaacaatc
    54061 accggtcatt accgagtcag catccagcac caccatgtag ctgtactggc tgccccagcg
    54121 acggcagaag tcatcgatat taccgctttt acgcttcacg cggcgacggc ggcggcgata
    54181 gaaaatctga ccttcgccac cgacttcagc gataagctcc atccaggctt tttgctctgc
    54241 gacgcagata tccgggttat aactgtcact aagaatgtag acatcaaagt gtttggcatt
    54301 cccggtggct tttactgatt cccacgttgc acgcaggcca gcaaaaacac ggttcacgtc
    54361 ttcgttacag ataggcatga tcaacgccgt gcgatgctcc gggtttaatg gttcatcgcc
    54421 aactgttgac gcagatatac tgtatttatc gcgaccaata agcagttgca ggaagcccat
    54481 taacgccgtc cagaatccgg cggacaccca acagaacagt accgcaaaga ggatcaggat
    54541 accggtttgc agcatataag gcagaagctg cataaaggaa acccacaaat cctgaccaac
    54601 catatccata ggattaatca gcgcccaacc ctgataagga agaatggtct tcatatacca
    54661 ggtcgcgacg acagtttgcg cgagcgtcag gatcaacaga atgtaacggc ggatggtacc
    54721 gacggtacgc cacttttgct cgctctcctg ctcttctttg gtcaaacgag ccagatagcg
    54781 cggcgtgaca tcgcgtccac gcaggcgatc ccagaaacgg cctaccgggt tggtacgcca
    54841 cgggtcggga aacatcgagg agcgttttgc ttctggcatc gccttcagct gatcgcgccc
    54901 ttcgtcgtct ttaattaact gtccatcagc aagtgaatct ggccaggctt gttccagacg
    54961 cgcctttacc gagccttgcg gggaatcatc ctcccgcgcc caggtgcggt gttcggcatc
    55021 cagcgcctga tgaacggcgc ggatatcagt cttcggcaat gccgctttct cgcttgcggc
    55081 gatgggcatt gcgtcaatgt actcagttgt cttattcatt ggcaggtaac tggtagctcc
    55141 aggtttcact caacgtctga tcggcattca ccagcgcagc acgcatttca gtggttttct
    55201 tggcatcttt cactttcaca cgcatcacca gacgccagcc tttggtaacc gggttatagc
    55261 gcaccgtgct ttcaactatc tcaccattat caccaatgct ggtttgcgct gtgaccgggg
    55321 tatcctctgg cagttttttc atctctgcgc cggtaaaatc gaccacaaag gcgatagtac
    55381 cgtcaggctg gcgaatcagg ttcgactgct tcacatcccc cgttgaacga cgcgtttgtt
    55441 gcacccatgc gttatctggc gcatgcagtt tgtcttcatc acggctgaag gtgatggtgt
    55501 atttaaagtt catctcttta cccggctccg gcagctgatc cggcgtccag taagcgacga
    55561 tgttatcgtt ggtttcatcg ttggttggaa tttccaccag ctcaacgctg cctttacccc
    55621 actccccttt cggagtcacc catgcgcttg gacgaagatc gtaacgatca tcgagatctt
    55681 caaagcggga gaaatcacga ccgcgctgca acagaccgaa gccttgcggg ttctccatcg
    55741 agaagctgct gaccgctaaa tgtttcgggt tattcaacgg acgccagatc cattcgccat
    55801 taccggcatg gatagacaga ccgttagagt cgtgcaactc cggacgatag ttatttgcag
    55861 gcgacggttg gttcggccca aacaggaaca tactggttaa cggtgcaacc cccagtttgc
    55921 cgactttatc gcgcagatag attttcgact gcacatccac aaccgtgtca cgccctggca
    55981 taaccacgaa tttgtaagca cctgtcgcgc gcggcgagtc aagcaatgca taaatggtta
    56041 aacgtttatc agtcggtttt ggacgctcga tccagaactc tttgaagcgt ggaaattctt
    56101 cacccgatgg caaggcggta tcaattgcca ggccgcgggc agaaaggcca taaacctgac
    56161 ctgcaccaat cacgcggaaa tagctggccc cgagcatgct gacgatttca tcgtttttat
    56221 ctttgctgtt gatcgggtaa agcactttaa aaccggcaaa accaaggtct tttaccgtgt
    56281 ctttgtcatg ctgaacatcg ccgaaagtga aataatccgg gctgtatttg attcgtttga
    56341 ctgcggtggc agtcacttca tttattttga ccggggtatc gaagtacata ccctgatggt
    56401 agaactcgag tttgaatggg gtcttcagat tgttccagta cgctttgtca tgattaaact
    56461 ggatctgctg atagtccgcg tatttcatat cgcggaaaac ggagggcaag ttgcttttgg
    56521 gcgcctcata gcctttcccg gctaaggatt gagcttgctt tgcgacatca tcaatactga
    56581 aagcccagct tgaagatgta tacagggtta acattactgc agcactcaac caacgcattt
    56641 tcatcatttg tagtttatgt ttcataatta gtaagcactt ccccctttgt gtgcttatat
    56701 cgatccgatc tattttaatg gataaccagc cattccgaca acagaatccc ggtatcgttc
    56761 agcacgctgg ctcatggatt aagcacctga ttgcaaccgt tttcactttc cgtgcttctc
    56821 ctaaagacag aagcatcgac ttcgtgtagg gtttgccagc aattttattt atcaaccgtc
    56881 ttacagacgc ttccattctg gttagtggta gcgatgatgc tatgcataaa aaccttgaag
    56941 cctgcgcctg gcgcggtcag gtcggtgtcg ctatggcaac aagcctaaag gcataacccg
    57001 acagggataa gacgaaaaat ccgagattag ttaaccatat atgaatccag tacccgcgca
    57061 acgtgaatat ttcctcgact ccatccgcgc ctggctgatg ttgttaggga tcccttttca
    57121 tatttcttta atctattcga gccatacatg gcatgtgaat agcgccgaac catcattgtg
    57181 gctgaccctt tttaatgact tcatccactc gttccgcatg caggtatttt tcgttatatc
    57241 cggctacttt tcctacatgc tttttttacg ctatcccttg aaaaaatggt ggaaagtacg
    57301 tgtcgaacgt gtaggtatcc cgatgttaac agccatcccc ctactgacat taccgcaatt
    57361 tattatgctg caatatgtca aaggaaaagc ggaaagttgg cctgggctgt cattgtatga
    57421 caaatataat acgttggcct gggaattaat atcacacctg tggtttttac tggtgttagt
    57481 agtcatgacg acgctgtgcg tatggatatt taagcgcatc agaaataatt tagaaaattc
    57541 tgataaaacg aataaaaaat tctcgatggt aaaactatcg gtgatttttt tatgcctcgg
    57601 catcggttat gcggtaataa gaagaacgat ttttattgtg tatccgccca ttctgagtaa
    57661 tggcatgttc aattttattg tcatgcaaac gctattttat ttaccgttct ttatcctcgg
    57721 cgcactggct ttcattttcc ctcatcttaa agccttgttt accacgccgt ctcgtggctg
    57781 taccctcgct gcagcattgg cgtttgtcgc ttatttactc aaccagcgct atggcagtgg
    57841 cgatgcctgg atgtacgaaa ccgagtcagt gatcaccatg gtcctcggtc tgtggatggt
    57901 gaatgtggtc ttctcctttg gccaccgttt gcttaacttc cagtcagcgc gggtgactta
    57961 ttttgttaac gcatcgctat ttatctatct ggttcaccac ccgttaacgc tgtttttcgg
    58021 cgcatacatt acaccgcaca tcacctccaa ctggcttggt tttctctgtg gcctgatatt
    58081 cgtagtaggg attgcgataa ttctgtatga aattcattta cgcatcccgt tactgaagtt
    58141 tttgttttct ggtaaaccgg ttgttaagcg tgagaacgat aaagcaccag cccgttaagc
    58201 cacatttaca ataaccattc cacgggcaat atcgacgcca gtctgaccat aacccgcttc
    58261 cagaaactgg tggcgggttc ttttttgaga ataatctctt tctttgcatg acgatcaacc
    58321 cagttgatcc gtccccacct gtccagacgg agctgccagg ccgcatcata ctggctctga
    58381 ataaagcgtt tatcaattaa ctgtgccagc gtttcgctct ctatcacgaa gcccatttca
    58441 gtattgagca atgttgaacg cggatcgaaa ttgaaagagc cgataaacac cgttttacca
    58501 tcgatgctaa aggttttagc atgcaggctg gctccggaat taccggttat gccgcgatcg
    58561 tgtaacgtac tactttgttc acgcgtcggc ttgagttcat ataattccac gccatagcgg
    58621 agcaattttt tgcgccagcg cgcgtatccg gcatggacga cagcaacatc gttagcggca
    58681 agagaattgg ttaggatcgc aatctttacc ccttttctca ccatccgtaa gagttgcgcc
    58741 acacctgcgc gtgtcggtac aaaataggaa gagataatat cgatgcgttc actgggtgag
    58801 cccatgatat cgaacaggcg ctgcggtaac agtgaatgcc gttttgcctt gccctcccct
    58861 ttcgccggat catcacttaa taaacgtgtt ttcgcccaga taagcggcaa cgttccatca
    58921 accagatgat ttataaacgg actggattcc attttgcgta agtaacgatg cgtcataaca
    58981 tcgttatgcc aggaggcggg taactcgatg cgatccgcca tttcaccttc cgggacatcc
    59041 agcacttgct gtaagggtga aaccgatttg caataccagt agcgggcgaa atcatcggca
    59101 acgtcctcta ccacgggccc tattgccata acatctaaat ccgaaaaaag tggctcttcc
    59161 cctgccccaa aataggcatc accaatattt cgccccccta ccagcgtcac cacgccatcg
    59221 acagtgaaac ttttattgtg catacggcga ttgagacggg aaaagtcggt gatataacca
    59281 agcggacgca gcaagcgaaa cgagaaagga ttaaaaagcc ggacttcaat gcggggatgg
    59341 ctgtcaagca agcgtaaaat gtcgtcaagt ccgggcgtat tgttgtcgtc cagcaacaaa
    59401 cggacgcgaa cgccacgctt tgctgcggct aacagggcgg aaaacagtaa ccgacccgac
    59461 atatcgtcct gccagatgta atactgaaca tccagcgtat gctctgccat ttcggccaga
    59521 cgataccggg cggcaaacgc atccagactt ttctccagag ggaaaagacc acactgaccg
    59581 ggatgttgcg aacacagtgg cagcaccgcg ctcgccagcc ggggcaaatc attcatctcc
    59641 ttgttgggta aggagtcttt cgtagaggtg ggcgttttct tcatcataac agacaaagta
    59701 tacctgttcg ggtaaagcgt gacgggtaat aaattctgaa acggttttaa ctgcgatttc
    59761 agccgctgcc gcacgagggt aaccataaac cccagtactg attgcaggaa aagccactga
    59821 cgtatagctg tttgccgcca ccagtcgtag gctattgaga taggcatcct gcaaaagctg
    59881 gtcttcgttt tgttcaccac cacgccagac tggcccgacg gtgtgcacta cggctttagc
    59941 gggaagagcg cctgcaagcg taataacggc atgccccgta gggcaatcgc cctgctgttg
    60001 cctgactttt aaacaggcat ccagcagggc cggacccgct gagcgatgaa tggccccatc
    60061 gacgccgccg cctcccatta atgacggatt agccgcattc acaatcacat caacggccag
    60121 tttggtaata tcaccctgca caacatgaat acgcgttttc ataacgcctc cttacacctt
    60181 cttgtttctt aagtgtacag caggcttttt ggttaaatcg catttttctg ctcagcaacg
    60241 tgcgttgttc agaaacttag ttatattcga tgttcattac agccagcttt ttctgtttat
    60301 caagatactg cacttttact gaggctattt gcgcgttttt aacattaccg ctcattaacg
    60361 ctttgctgga ataggttttg cccggaacag aaccattctg tgggcagttc atttctacgg
    60421 gtgatgactg ggtgctgacg tcacatgccg gttccacaat ttggccataa aaatggatcc
    60481 ccccccttgc gcggtgcttc ctgcgatggc aataaaagga aaaagcaaac tgccgagcat
    60541 aagagagttt aaaaaaggtc tgaacattta ttctatttcc tcaatgatta gtcatccttg
    60601 agggttgtgt tatccatact ttcaggttgg ctgattcgca gcagaccatt ctctccagat
    60661 tcatcttatg ctcgatattt caacaaatta agacttttct gaagagggcg gccattgttg
    60721 tgataaatga agtgactgtc catcagaaac agtaacaact attttcaccc gatcttccgg
    60781 ggaaatattt aaactcaact tcgtcaaagc aataggttga ttagcaggca atgagagggt
    60841 cttttcttgc ttcgtctgac tttgccctga actgccttcg cgcagggaca atatttgtac
    60901 tctgcacaga caagattgag taagagtgac ttcaggaata atggtataca catccccttg
    60961 ctgggtcgta ttaaaggtta tctggctgga aagtgccgca aggagtaata acgcattcat
    61021 attcttctcc cgaaaaaaaa cagggcttgc gccctgtttc tgtaatacaa atgatgtatt
    61081 agtactgatg agcggtcgcg ttgttaccaa agccaacctg agtcacgttg acggaggagt
    61141 tagatgcagt ctggtcaact gcagcaccgt tgccaccacc gaactgttta acagtcattt
    61201 cagaattttt gccgttccac tgatcaagag tggcgctgtt accgaagcca cgttgggtca
    61261 gatcgattga gctgtcatct gagccctgac ctacatctgc accattacca ccgccatgct
    61321 gggtaatagt caagtcagag ttacgggcat cagtttgcag agcaagtgca gagttaccgc
    61381 caccgtactg gtaaatgttc agctctgaat ttgggccgct attattaccg ccaccaccgt
    61441 ggttaccgcc gccgccgtac tgaggaacaa cacctgccag agcgctaccg gagaatacga
    61501 ttgctgcaat tgctgctact tttaaaagtt tcatgtaaaa cccccatcgg attgatttaa
    61561 aagtcgaatg gaaattaacg ttgtgtcacg cgaatagcca tttgcgactg tctctgcact
    61621 acaattgccg ttttttgagt accatactgt gtaatatttg ctttattacc agaacctttc
    61681 tggataatca tcgcagtatt accataagca ccttgcgaaa tactggcatc gttggcactg
    61741 cccgcctgat caatatatgc aaggttataa tctcctgtct ggtcaatctt tgcccggttg
    61801 ctactacctt cttgcgcaac aaccgccaaa agttttgagc ctccctgccg taactgagca
    61861 ctattattcg tcccagcttg accaattatg gctgcctgat taaatgaaga cttactcaat
    61921 tcatttaccg cgaagttata ttctgaatta gctaaatcat aacctgctgc ggctgcaatc
    61981 ccaggcgcac ccagtattgt taacatcata aataacaatt tgtttttcat gttgtcaccc
    62041 tggacctggt cgtacattta agaaattaaa tcatttcaac ttggttgtta acgcaacctg
    62101 tattttgtta acgctgcgtt acgatggaaa gtatgtctgc ggaaatattt ttaataactc
    62161 acccgcgcgt tgtatttttc tttttttgtt cataccaaag tattaaaacc cacgtaaata
    62221 cgctgttatc tacgcaaaaa atattttgtt ttcttttaaa tctccgtttt ccgctatcaa
    62281 aaatcaccag acagtcattt ttcttgcccg tcgctgattg ctgcgatatg tcttgcgcac
    62341 aagccgtgac aaacctcgtc tttttgcagt aaaaaattgt ccacggaggt gcggagaaaa
    62401 aacaagaacg ttttacatga cgaaaggac
//
LOCUS       DAPGUL010000012        60848 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.012, whole genome shotgun sequence.
ACCESSION   DAPGUL010000012 DAPGUL010000000
VERSION     DAPGUL010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 60848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60848
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.012"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            37..753
                     /locus_tag="RHX21_000902"
     CDS             37..753
                     /locus_tag="RHX21_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HDV1986129.1"
                     /translation="MVAKINLLSRLTPLLFVFAPFLAQSNMTVYPMAVSINSQGEGNV
                     RVISKSNEVQYIKATVFRIDNPSTPQENEVEIKSGDANHLVVMPPKFALPAGSSKTVR
                     FVAMEPEQKEKNYRVKFEAVPSIDDVATDKKDLSMQLTVNLIWGIVVSVPPQQPIAKL
                     EVNAAQKLVNAGNQRLKILTIAYCKNNSKENCKIQTVNKNIFPGQERNLESISGYDKI
                     VVKYNNWITKDNGEFELAVH"
     gene            783..1283
                     /locus_tag="RHX21_000903"
     CDS             783..1283
                     /locus_tag="RHX21_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV1986130.1"
                     /translation="MKKVFAKSLLVAAMFSVAGSALAVQKDITVTANVDAALDMTQTD
                     NTALPKAVEMQYLPGQGLQSYQLMTKIWSNDVTKDVKMQLVSPAQLVQSLDASKIVPL
                     TVTWGGEEIKADAATTFTATKIFASDALTNGSLAKNLMFAQTTKGVLETGIYRGVVSI
                     YLSQDI"
     gene            1375..4059
                     /locus_tag="RHX21_000904"
     CDS             1375..4059
                     /locus_tag="RHX21_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001666746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcfC E-set like domain-containing protein"
                     /protein_id="HDV1986131.1"
                     /translation="MDKKLLALLILASLSPAEATLTKIPAGFEVIAQGQQEYIEVYFS
                     GKSLGKYYAMVNLDTVTFLDPASLYNKLELDVDDQKIAHIVKEKLSQPLARHGELACG
                     YVRTDSGCGFLNTDTLEIIYNDEESSATLFINPQWNSAFDAKSLYLNPDKNTVNAFIH
                     QQDINVLAQDDYQSLSIQGNGALGITENSYIGAHWNFNGYDADDVSDSNADVSDLYYR
                     YDFLRRYYVQAGRMDNRTLFNAQGGNFTFNFLPLGAIDGMRIGSTLSYLNQAQSQQGT
                     PVMVLLSRNSRVDAYRNEQLLGSFYLNSGSQFIDTSSFPPGSYSVALKVYENNQLTRT
                     ELVPFTKTGGLTDGNAQWFLQAGKTTSQVSDDESSAYQLGVRLPLHPQYELYAGLANA
                     DDVSAFELGNNWTADLGGVGNLAISASVFRNDDGGKGDMQQANWSNPGWPTLGFYRTN
                     SDGDACTTDSRESYNALSCYESISATVSQNFVGWNMMLGYTRTQNNTDDSLRWDKQQS
                     FENNYLRQTTAQSISETVQLSASRAFVMRDWILSTSVGVFHRNDNGGDNDDNGLYLSF
                     SLSDTPTMDSNNNSHSTNVSTDYRYSEQDGDQTSWQLSHTFYNDSFSHKELGVTVGGL
                     NTDTINSAVNGRWDGQYGNVYATVSDSYDRKNHDHLSAFTGTYSSTLAVSRYGVNLGA
                     SGTDDLLGAVLVDVKGFSEQDEESQDLQLEARVAGSRTLQLGQSDSVLFPYPGFQSGF
                     VEVNDSSQGNQQGTTNIINGAGNRELMLLPGKLRYREVSASFNYNYIGRLLLPAAVKK
                     FPIVGLNSAMLLVAEDGGFTLEINGSEKELYLLSGQQFLKCPLSVVKKRASIRYSGDV
                     TCSVVTYSQLPESIQVQAQLKQPKLRGNVQTAQREVAP"
     gene            4056..5144
                     /locus_tag="RHX21_000905"
     CDS             4056..5144
                     /locus_tag="RHX21_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001352530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein CblD"
                     /protein_id="HDV1986132.1"
                     /translation="MRNRLIAAILGLFGTLTGVQAAPDVTSEITYDLASGRADYYFWK
                     DEASAGNNGYMWYECSYPDLQQTCTANGNISTVQIYLTEQRSGMRWPVKLKGFKTAIV
                     SSDEAPPGCKGGKGLQTNLKDSNRSSCTEDGQHYYIYDTKFLTLYLEQTEMKNLPIGG
                     VWKGKVKLHSNSPAQDYFANITLNTLDPNHIDVFFPEFAHATPRVQLDLHPTGSVNGS
                     NYAQDLTMLDMCLYDGFNGNAISYEIMLKDEGRPAAGRRDGYFSIYRQGGTTTDEGER
                     IDYRVKMYNPETGGQIDVRNNENMVWNSINLKRVRPVVLPGIRYAVMCVPTPLTLAVD
                     KFSVMDKQAGYYMGKLSVIFTPSLPTIN"
     gene            complement(5232..6530)
                     /gene="exuT"
                     /locus_tag="RHX21_000906"
     CDS             complement(5232..6530)
                     /gene="exuT"
                     /locus_tag="RHX21_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708898.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexuronate transporter ExuT"
                     /protein_id="HDV1986133.1"
                     /translation="MRKIKGLRWYMIALVTLGTVLGYLTRNTVAAAAPTLMEELNIST
                     QQYSYIIAAYSAAYTVMQPVAGYVLDVLGTKIGYAMFAVLWAVFCGATALAGSWGGLA
                     IARGAVGAAEAAMIPAGLKASSEWFPAKERSIAVGYFNVGSSIGAMIAPPLVVWAIVM
                     HSWQMAFIISGALSFIWAMAWLIFYKHPRDQKHLTDEERDYIINGQEAQHQVSTAKKM
                     SVGQILRNRQFWGIALPRFLAEPAWGTFNAWIPLFMFKVYGFNLKEIAMFAWMPMLFA
                     DLGCILGGYLPPLFQRWFGVNLIVSRKMVVTLGAVLMIGPGMIGLFTNPYVAIMLLCI
                     GGFAHQALSGALITLSSDVFGRNEVATANGLTGMSAWLASTLFALVVGALADTIGFSP
                     LFAVLAVFDLLGALVIWTVLQNKPAIEVAQETHNDPAPQH"
     gene            7013..8425
                     /gene="uxaC"
                     /locus_tag="RHX21_000907"
     CDS             7013..8425
                     /gene="uxaC"
                     /locus_tag="RHX21_000907"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HDV1986134.1"
                     /translation="MTPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAED
                     YRFKNLYDIWLKGDHYKWRAMRTNGVAERLCTGDASDREKFDAWAATVPHTIGNPLYH
                     WTHLELRRPFGITGKLLSPSTADEIWNECNELLAQDNFSARGIMQQMNVKMVGTTDDP
                     IDSLEHHAEIAKDGSFTIKVLPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADL
                     QTALTKRLDHFAAHGCKVSDHALDVVMFAEANEAELDSILARRLAGEPLSEHEVAQFK
                     TAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDSINDRPMAEELSKLL
                     SKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMER
                     QMTQLAQLGLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVEAGEAPADINLLG
                     EMVKNICFNNARDYFAIELN"
     gene            8440..9927
                     /gene="uxaA"
                     /locus_tag="RHX21_000908"
     CDS             8440..9927
                     /gene="uxaA"
                     /locus_tag="RHX21_000908"
                     /EC_number="4.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HDV1986135.1"
                     /translation="MQYIKIHALDNVAVALADLAEGTEVSVDNQTVTLRQDVARGHKF
                     ALTDIAKGANVIKYGLPIGYALADIAAGEHVHAHNTRTNLSDLDQYRYQPDFQDLPAQ
                     AADREVQIYRRANGDVGVRNELWILPTVGCVNGIARQIQNRFLKETNNAEGTDGVFLF
                     SHTYGCSQLGDDHINTRTMLQNMVRHPNAGAVLVIGLGCENNQVAAFRETLGDIDPER
                     VHFMICQQQDDEIEAGIEHLHQLYNVMRNDKREPGKLSELKFGLECGGSDGLSGITAN
                     PMLGRFSDYVIANGGTTVLTEVPEMFGAEQLLMDHCRDEATFEKLVTMVNDFKQYFIA
                     HDQPIYENPSPGNKAGGITTLEDKSLGCTQKAGSSVVVDVLRYGERLKTPGLNLLSAP
                     GNDAVATSALAGAGCHMVLFSTGRGTPYGGFVPTVKIATNSELAAKKKHWIDFDAGQL
                     IHGKAMPQLLEEFIDTIVEFANGKQTCNERNDFRELAIFKSGVTL"
     gene            10010..10561
                     /locus_tag="RHX21_000909"
     CDS             10010..10561
                     /locus_tag="RHX21_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgjV family protein"
                     /protein_id="HDV1986136.1"
                     /translation="MTAYWLAQGVGVIAFLIGITTFFNRDERRFKKQLSVYSAVIGVH
                     FFLLGTYPAGASAILNAIRTLITLRTRSLWVMAIFIVLTGGIGLAKFHHPVELLPVIG
                     TIVSTWALFRCKGLTMRCVMWFSTCCWVIHNFWAGSIGGTMIEGSFLLMNGLNIIRFW
                     RMQKRGIDPFKVEKTPPAVDERG"
     gene            complement(10566..11810)
                     /gene="sstT"
                     /locus_tag="RHX21_000910"
     CDS             complement(10566..11810)
                     /gene="sstT"
                     /locus_tag="RHX21_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HDV1986137.1"
                     /translation="MTTQRSPGLFRRLAHGSLVKQILVGLVLGILLAWISKPAAEAVG
                     LLGTLFVGALKAVAPILVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVVF
                     SFAFPSTLHLSSSAGDISPPSGIVEVMRGLVMSMVSNPIDALLKGNYIGILVWAIGLG
                     FALRHGNETTKNLVNDMSNAVTFMVKLVIRFAPIGIFGLVSSTLATTGFSTLWGYAQL
                     LVVLVGCMLLVALVVNPLLVWWKIRRNPFPLVLLCLRESGVYAFFTRSSAANIPVNMA
                     LCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVNTLGIPVDLPTALLLSVVA
                     SLCACGASGVAGGSLLLIPLACNMFGISNDIAMQVVAVGFIIGVLQDSCETALNSSTD
                     VLFTAAACQAEDDRLANSALRN"
     gene            complement(12426..13391)
                     /gene="alx"
                     /locus_tag="RHX21_000911"
     CDS             complement(12426..13391)
                     /gene="alx"
                     /locus_tag="RHX21_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family membrane protein Alx"
                     /protein_id="HDV1986138.1"
                     /translation="MNTVGTPLLWGGFAVVVAIMLAIDLLLQGRRGAHAMTMKQAAAW
                     SLVWVTLSLLFNAAFWWYLVQTEGRAVADPQALAFLTGYLIEKSLAVDNVFVWLMLFS
                     YFSVPAALQRRVLVYGVLGAIVLRTIMIFTGSWLISQFDWILYIFGAFLLFTGVKMAL
                     AHEDESGIGDKPLVRWLRGHLRMTDTIDNEHFFVRKNGLLYATPLMLVLILVELSDVI
                     FAVDSIPAIFAVTTDPFIVLTSNLFAILGLRAMYFLLAGVAERFSMLKYGLAVILVFI
                     GIKMLIVDFYHIPIAVSLGVVFGILVMTFIINAWVNYRHDKQRGE"
     gene            complement(13674..14660)
                     /locus_tag="RHX21_000912"
     CDS             complement(13674..14660)
                     /locus_tag="RHX21_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417558.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDV1986139.1"
                     /translation="MIRFAVIGTNWITRQFVEAAHESGKYKLTAVYSRSLEQAQHFAN
                     DFSVEHLFTSLEAMAESDAIDAVYIASPNALHFSQTQLFLSHKIHVICEKPLASNLAE
                     VDAAIACARENQVVLFEAFKTACLPNFHLLRQALPKVGKLRKVFFNYCQYSSRYQRYL
                     DGENPNTFNPSFSNGSIMDIGFYCLASAVALFGEPKSVQATASLLASGVDAHGVVVMD
                     YGDFSVTLQHSKVSDSVLASEIQGEAGSLVIEKLSECQKVCFVPRGSQMQDLTQPQHI
                     NTMLYEAELFATLVDEHLVDHPGLAVSRITAKLLTEIRRQTGVIFPADSVKL"
     gene            complement(14739..15422)
                     /locus_tag="RHX21_000913"
     CDS             complement(14739..15422)
                     /locus_tag="RHX21_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001183047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin high temperature exclusion protein"
                     /protein_id="HDV1986140.1"
                     /translation="MQPRLLLRICFSRRTLKIGCLLLLIAGATIFIADRVMVNASKQL
                     TWSDVNAVPARNVGLLLGARPGNRYFTRRIDTAAALYHAGKVKWLLVSGDNGRKNYDE
                     ASGMQQALIAKGVPAKVIFCDYAGFSTLDSVVRAKKVFGENHITIISQEFHNQRAIWL
                     AKQYGIDAIGFNAPDLNMKHGFYTQLREKLARVSAVIDAKILHRQPKYLGPSVMIGPF
                     SEHGCPAKE"
     gene            complement(15499..16002)
                     /locus_tag="RHX21_000914"
     CDS             complement(15499..16002)
                     /locus_tag="RHX21_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311994.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HDV1986141.1"
                     /translation="MNNLTYLQGYPEQLLSQVRTLINEQRLGDVLAKRYPGTHDYATD
                     KALWQYTQDLKNQFLRNAPPINKVMYDNKIHVLKNALGLHTAVSRVQGGKLKAKAEIR
                     VATVFRNAPEPFLRMIVVHELAHLKEKEHNKAFYQLCCHMEPQYHQLEFDTRLWLTQL
                     SLGQDKI"
     gene            16087..17223
                     /gene="rlmG"
                     /locus_tag="RHX21_000915"
     CDS             16087..17223
                     /gene="rlmG"
                     /locus_tag="RHX21_000915"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417555.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (guanine(1835)-N(2))-methyltransferase
                     RlmG"
                     /protein_id="HDV1986142.1"
                     /translation="MSHLDNGFRSLTLQRFPATDDVNPLQAWEAADEYLLQQLDDTEI
                     RGPVLILNDAFGALSCALAEHKPYSIGDSYISELATRENLRLNGIDESSVKFLDSTAD
                     YPQQPGVVLIKVPKTLALLEQQLRALRKVVTSDTRIIAGAKARDIHTSTLELFEKVLG
                     PTTTTLAWKKARLINCTFNEPPLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGAR
                     FFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRMNVETNM
                     PEALDRCEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAWEMFHHARRCLKING
                     ELYIVANRHLDYFHKLKKIFGNCTTIATNNKFVVLKTVKLGRRR"
     gene            17414..17497
                     /locus_tag="RHX21_000916"
                     /pseudo
     CDS             17414..17497
                     /locus_tag="RHX21_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311992.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HigB family
                     toxin"
     gene            17494..17910
                     /gene="higA"
                     /locus_tag="RHX21_000917"
     CDS             17494..17910
                     /gene="higA"
                     /locus_tag="RHX21_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin HigA"
                     /protein_id="HDV1986143.1"
                     /translation="MIAIADILQAGEKLTAVAPFLAGIQNEEQYTQALELVDHLLLND
                     PENPLLDLVCAKITAWEESAPEFAEFNAMAQAMPGGIAVIRTLMDQYGLTLSDLPEIG
                     SKSMVSRVLSGKRKLTLEHAKKLATRFGISPALFID"
     gene            complement(17955..19973)
                     /gene="fadH"
                     /locus_tag="RHX21_000918"
     CDS             complement(17955..19973)
                     /gene="fadH"
                     /locus_tag="RHX21_000918"
                     /EC_number="1.3.1.34"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 2,4-dienoyl-CoA reductase"
                     /protein_id="HDV1986144.1"
                     /translation="MSYPSLFAPLDLGFTTLKNRVLMGSMHTGLEEYPDGAERLAAFY
                     AERARHGVALIVSGGIAPDLTGVGMEGGAMLNDASQIPHHRTITEAVHQEGGKIALQI
                     LHTGRYSYQPHLVAPSALQAPINRFVPHELTHEEILQLIDDFAHCAQLAREAGYDGVE
                     VMGSEGYLINEFLTLRTNQRSDQWGGDYRNRMRFAVEVVRTVRERVGNDFIIIYRLSM
                     LDLVEGGGTFAETVELAQAIEAAGATIINTGIGWHEARIPTIATPVPRGAFTWVTRKL
                     KGHVSLPLVTTNRINDPQVADDILSRGDADMVSMARPFLADAELLSKAQSGRADEINT
                     CIGCNQACLDQIFVGKVTSCLVNPRACHETKMPILPAVQKKNLAVVGAGPAGLAFAIN
                     AAARGHQVTLFDAHSEIGGQFNIAKQIPGKEEFYETLRYYHRMIEVTGVTLKLNHTVT
                     ADQLQAFDETILASGIVPRVPPIDGIDHPKVLSYLDVLRDKAPVGNKVAIIGCGGIGF
                     DTAMYLSQPGESTSQNIARFCNEWGIDSSLQQAGGLSPQGMQIPRSPRQIVMLQRKAS
                     KPGQGLGKTTGWIHRTTLLSRGVKMIPGVSYQKIDDDGLHVVINGETQVLAVDNVVIC
                     AGQEPNRALAQPLIDSGKTVHLIGGCDVAMELDARRAIAQGTRLALEI"
     gene            complement(20299..22650)
                     /gene="ygjK"
                     /locus_tag="RHX21_000919"
     CDS             complement(20299..22650)
                     /gene="ygjK"
                     /locus_tag="RHX21_000919"
                     /EC_number="3.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDV1986145.1"
                     /translation="MKIKTILTPVTCALLISFSAHAANADNYKNVINRTGAPQYMKDY
                     DYDDHQRFNPFFDLGAWHGHLLPDGPNTMGGFPGVALLTEEYINFMASNFDRLTVWQD
                     GKKVDFTLEAYSIPGALVQKLTAKDVQVEMTLRFATPRTSLLETKITSNKPLDLVWDG
                     ELLEKLEAKEGKPLSDKTIAGEYPDYQRKISATRDGLKVTFGKVRATWDLLTSGESEY
                     QVHKSLPVQTEINGNRFTSKAHINGSTTLYTTYSHLLTAQEVSKEQMQIRDILARPAF
                     YLTASQQRWEEYLKKGLTNPDATPEQTRVAVKAIETLNGNWRSPGGAVKFNTVTPSVT
                     GRWFSGNQTWPWDTWKQAFAMAHFNPDIAKENIRAVFSWQIQPGDSVRPQDVGFVPDL
                     IAWNLSPERGGDGGNWNERNTKPSLAAWSVMEVYNVTQDKAWLAEMYPKLVAYHDWWL
                     RNRDHNGNGVPEYGATRDKAHNTESGEMLFTVKKGNKEETQSGLNNYARVVEKGQYDS
                     LEIPAQVAASWESGRDDAAVFGFIDKEQLDKYVASGGKRSDWTVKFAENRSQDGTLLG
                     YSLLQESVDQASYMYSDNHYLAEMATILGKPEEAKRYRQLAQQLADYINTCMFDPTTQ
                     FYYDVRIEDKPLANGCAGKPIVERGKGPEGWSPLFNGAATQANADAVVKVMLDPKEFN
                     TFVPLGTAALTNPAFGADIYWRGRVWVDQFWFGLKGMERYGYRDDALKLADTFFRHAK
                     GLTADGPIQENYNPLTGAQQGAPNFSWSAAHLYMLYNDFFRKQ"
     gene            complement(22667..23737)
                     /gene="ygjJ"
                     /locus_tag="RHX21_000920"
     CDS             complement(22667..23737)
                     /gene="ygjJ"
                     /locus_tag="RHX21_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YgjJ"
                     /protein_id="HDV1986146.1"
                     /translation="MKLITAPCRALLALPFCYAFSAAGEEARPAEHDDTKTPAITSTS
                     SPSFRFYGELGVGGYMDLEGENKHKYSDGTYIEGGLEMKYGSWFGLIYGEGWTVQADH
                     DGNAWVPDHSWGGFEGGINRFYGGYRTNDGTEIMLSLRQDSSLDDLQWWGDFTPDLGY
                     VIPNTRDIMTALKVQNLSGNFRYSVTATPAGHHDESKAWLHFGKYDRYDDKYTYPAMM
                     NGYIQYDLAEGITWMNGLEITDGTGQLYLTGLLTPNFAARAWHHTGRADGLDVPGSES
                     GMMVSAMYEALKGVYLSTAYTYAKHRPDHADDETTSFMQFGIWYEYGGGRFATAFDSR
                     FYMKNASHDPSDQIFLMQYFYW"
     gene            complement(23871..25304)
                     /locus_tag="RHX21_000921"
     CDS             complement(23871..25304)
                     /locus_tag="RHX21_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDV1986147.1"
                     /translation="MSDTKRNTIGKFGLLSLTFAAVYSFNNVINNNIELGLASAPMFF
                     LATIFYFIPFCLIIAEFVSLNKNSEAGVYAWVKSSLGGRWAFITAYTYWFVNLFFFTS
                     LLPRVIAYASYAFLGYEYIMTPVATTIISMVLFAFSTWVSTNGAKMLGPITSVTSTLM
                     LLLTLSYILLAGTALVGGVQPADPITVDAMIPNFNWAFLGVTTWIFMAAGGAESVAVY
                     VNDVKGGSKSFVKVIILAGIFIGVLYSVSSVLINVFVSSKELKFTGGSVQVFHGMAAY
                     FGLPEALMNRFVGLVSFTAMFGSLLMWTATPVKIFFSEIPEGIFGKKTVELNENGVPA
                     RAAWIQFLIVIPLMIIPMLGSNTVQDLMNTIINMTAAASMLPPLFIMLAYLNLRAKLD
                     HLPRDFRMGSRRTGIIVVSMLIAIFAVGFVASTFPTGANILTIIFYNVGGIVIFLGFA
                     WWKYSKYIKGLTAEERHIEATPASNVD"
     gene            complement(25367..25816)
                     /locus_tag="RHX21_000922"
     CDS             complement(25367..25816)
                     /locus_tag="RHX21_000922"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase subunit beta"
                     /protein_id="HDV1986148.1"
                     /translation="MRIIDNLEQFRQIYASGKKWQRCVEAIENIDNIQPGVAHSIGDS
                     LTYRVETDSATDALFTGHRRYFEVHYYLQGQQKIEYAPKETLQVVEYYRDETDREYLK
                     GCGETVEVHEGQIVICDIHEAYRFICNNAVKKVVLKVTIEDGYFHNK"
     gene            complement(25813..28905)
                     /gene="ebgA"
                     /locus_tag="RHX21_000923"
     CDS             complement(25813..28905)
                     /gene="ebgA"
                     /locus_tag="RHX21_000923"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311985.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase subunit alpha"
                     /protein_id="HDV1986149.1"
                     /translation="MNRWENIQLTHENRLAPRAYFFSYDSVAQARTFARETSSLFLPL
                     SGQWNFHFFDHPLQVPEAFTSELMADWGHITVPAMWQMEGHGKLQYTDEGFPFPIDVP
                     FVPSDNPTGAYQRIFTLSDGWQGKQTLIKFDGVETYFEVYVNGQYVGFSKGSRLTAEF
                     DISAMVKTGDNLLCVRVMQWADSTYVEDQDMWWSAGIFRDVYLVGKHLTHINDFTVRT
                     DFDEAYCDATLSCEVVLENLAASPVVTTLEYTLFDGERVVHSSAIDHLAIEKLTSASF
                     AFTVEQPQQWSAESPYLYHLVMTLKDANGNVLEVVPQRVGFRDIKVRDGLFWINNRYV
                     MLHGVNRHDNDHRKGRAVGMDRVEKDLQLMKQHNINSVRTAHYPNDPRFYELCDIYGL
                     FVMAETDVESHGFANVGDISRITDDPQWEKVYVERIVRHIHAQKNHPSIIIWSLGNES
                     GYGCNIRAMYHAAKALDDTRLVHYEEDRDAEVVDIISTMYTRVPLMNEFGEYPHPKPR
                     IICEYAHAMGNGPGGLTEYQNVFYKHDCIQGHYVWEWCDHGIQAQDDNGNVWYKFGGD
                     YGDYPNNYNFCLDGLIYSDQTPGPGLKEYKQVIAPVKIHALDLTRGELKVENKLWFTT
                     LDDYTLHAEVRVEGETLATQQIKLRDVAPNSEAPLQITLPQLDAREAFLNITVTKDSR
                     TRYSEAGHSIATYQFPLKENTAQPVPFAPNNARPLTLEDDRLSCTVRGYNFAITFSKM
                     SGKPTSWQVNGESLLTREPKINFFKPMIDNHKQEYEGLWQPNHLQIMQEHLRDFAVEQ
                     SDGEVLIISRTVIAPPVFDFGMRCTYIWRIAADGQVNVALSGERYGDYPHIIPCIGFT
                     MGINGEYDQVAYYGRGPGENYADSQQANIIDIWRSTVDAMFENYPFPQNNGNRQHVRW
                     TALTNRHGNGLLVVPQRPINFSAWRYTQENIHAAQHCNELQRSDDITLNLDHQLLGLG
                     SNSWGSEVLDSWRVWFRDFSYGFTLLPVSGGEATAQSLASYEFGAGFFSTNLHSENKQ
                     "
     gene            complement(29089..30072)
                     /gene="ebgR"
                     /locus_tag="RHX21_000924"
     CDS             complement(29089..30072)
                     /gene="ebgR"
                     /locus_tag="RHX21_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator EbgR"
                     /protein_id="HDV1986150.1"
                     /translation="MATLKDIAIEAGVSLATVSRVLNDDPTLNVKEETKHRILEIAEK
                     LEYKTSSARKLQTGAVNQHHILAIYSYQQELEINDPYYLAIRHGIETQCEKLGIELTN
                     CYEHSGLPDIKNVTGILIVGKPTPALRAAACALTDNICFIDFHEPGSGYDAVDIDLAR
                     ISKEIIDFYINQGVNRIGFICGEDEPGKADIREVAFAEYSRLKQVVREEDIWRGGFSS
                     SSGYELAKQMLAREDYPKALFVASDSIAIGVLRAIHERGLNIPQDISLISVNDIPTAR
                     FTFPPLSTVRIHSEMMGSQGVNLVYEKARDGRALPLLVFVPSKLKLRGTTR"
     gene            30291..30623
                     /locus_tag="RHX21_000925"
     CDS             30291..30623
                     /locus_tag="RHX21_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HDV1986151.1"
                     /translation="METVAYADFARLEMRVGKIVEVKRHENADKLYIVQVDVGEKTLQ
                     TVTSLVPYYSEEELMGKTVVVLCNLQKAKMRGETSECMLLCAETDDGSESVLLTPERM
                     MPAGVRVV"
     gene            complement(30665..32044)
                     /gene="ygjG"
                     /locus_tag="RHX21_000926"
     CDS             complement(30665..32044)
                     /gene="ygjG"
                     /locus_tag="RHX21_000926"
                     /EC_number="2.6.1.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417544.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine aminotransferase"
                     /protein_id="HDV1986152.1"
                     /translation="MNRLPSSASALACSAHALNLIEKRTLDHEEMKALNREVIEYFKE
                     HVNPGFLEYRKSVTAGGDYGAVEWQAGGLNTLVDTQGQEFIDCLGGFGIFNVGHRNPV
                     VVSAVQNQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAALKL
                     AKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGNIEAM
                     RTALNECKKTGDDVAAVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTG
                     MGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFG
                     GNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMA
                     IEFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCELVIKAARKALA
                     AMRVSVEEA"
     gene            32462..33982
                     /gene="aer"
                     /locus_tag="RHX21_000927"
     CDS             32462..33982
                     /gene="aer"
                     /locus_tag="RHX21_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311981.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerotaxis sensor receptor Aer"
                     /protein_id="HDV1986153.1"
                     /translation="MSSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGFT
                     LQELQGQPHNMVRHPDMPKAAFADMWFTLKKGEPWSGIVKNRRKNGDHYWVRANAVPM
                     VREGKISGYMSIRTRATDEEIAAVEPLYKALNAGRTSKRIHKGLVVRKGWLGKLPSLP
                     LRWRARGVMTLMFILLAAMLWFVAAPVVTYFLCVLVVLLASACFEWQIVRPIENVARQ
                     ALKVATGERNSVEHLNRSDELGLTLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAK
                     GTDELNEHTQQTVDNVQQTVATMNQMAASVKQNSATASAADKLSITASNAAVQGGEAM
                     TTVIKTMDDIADSTQRIGTITSLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGE
                     VRHLASRSANAANDIRKLIDASADKVQSGSQQVHAAGRTMEDIVAQVKNVTQLIAQIS
                     HSTLEQADGLSSLTRAVDELNLITQKNAELVEESAQVSAMVKHRASRLEDAVTVLH"
     gene            complement(34136..34759)
                     /gene="nfeR"
                     /locus_tag="RHX21_000928"
                     /gene_synonym="yqjI"
     CDS             complement(34136..34759)
                     /gene="nfeR"
                     /locus_tag="RHX21_000928"
                     /gene_synonym="yqjI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NfeR"
                     /protein_id="HDV1986154.1"
                     /translation="MSHHHEGCCKHEGQPRHEGCCKGEKSEHEHCGHGHQHEHGQCCG
                     GRHGRGGGRRQRFFGHGELRLVILDILSRDDSHGYELIKAIENLTQGNYTPSPGVIYP
                     TLDFLQEQSLITIREEEGGKKQIALTEQGAQWLEENREQVEMIEERIKARCVGAALRQ
                     NPQMKRALDNFKAVLDLRVNQSDISDAQIKKIIAVIDRAAFDITQLD"
     gene            35047..35811
                     /gene="nfeF"
                     /locus_tag="RHX21_000929"
     CDS             35047..35811
                     /gene="nfeF"
                     /locus_tag="RHX21_000929"
                     /EC_number="1.16.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent ferric chelate reductase"
                     /protein_id="HDV1986155.1"
                     /translation="MNNSPRYPQRVRNDLRFRELTVLRVERISAGFQRIVLGGEALDG
                     FTSRGFDDHSKLFFPQSDAHFVPPTVTEEGIVWPEGPRPPSRDYTPLYDELRHELAID
                     FFIHDGGVASGWAMQAQPGDKLTVAGPRGSLVVPEDYAYQLYVCDESGMPALRRRLET
                     LSKLAVKPQVSALVSVRDNACQDYLAHLDGFNIEWLAHDEQAVDARLAQMQIPADDYF
                     IWITGEGKVVKNLSRRFEAEQYDPQRVRAAAYWHAK"
     gene            complement(35865..35940)
                     /locus_tag="RHX21_000930"
     tRNA            complement(35865..35940)
                     /locus_tag="RHX21_000930"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(35905..35907),aa:Ile,seq:cat)
     gene            36065..36571
                     /gene="mug"
                     /locus_tag="RHX21_000931"
     CDS             36065..36571
                     /gene="mug"
                     /locus_tag="RHX21_000931"
                     /EC_number="3.2.2.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G/U mismatch-specific DNA glycosylase"
                     /protein_id="HDV1986156.1"
                     /translation="MVEDILAPGLRVVFCGINPGLSSAGTGFPFAHPANRFWKVIYQA
                     GFTDRQLKPQEAQHLLDYRCGVTKLVDRPTVQANEVSKQELHAGGRKLIEKIEDYQPQ
                     ALAILGKQAYEQGFSQRGAQWGKQTLTIGSTQIWVLPNPSGLSRVSLEKLVEAYRELD
                     QALVVRGR"
     gene            complement(36650..38491)
                     /gene="rpoD"
                     /locus_tag="RHX21_000932"
     CDS             complement(36650..38491)
                     /gene="rpoD"
                     /locus_tag="RHX21_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HDV1986157.1"
                     /translation="MEQNPQSQLKLLVTRGKEQGYLTYAEVNDHLPEDIVDSDQIEDI
                     IQMINDMGIQVMEEAPDADDLMLAENTADEDAAEAAAQVLSSVESEIGRTTDPVRMYM
                     REMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARLSD
                     LITGFVDPNAEEDLAPTATHVGSELSQEDLDDDEDEDEEDGDDDSADDDNSIDPELAR
                     EKFAELRAQYVVTRDTIKAKGRSHAAAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVM
                     MDRVRTQERLIMKLCVEQCKMPKKNFITLFTGNETSDTWFNAAIAMNKPWSEKLHDVS
                     EEVHRALQKLQQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEANLRLVISIAK
                     KYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTI
                     RIPVHMIETINKLNRISRQMLQEMGREPTPEELAERMLMPEDKIRKVLKIAKEPISME
                     TPIGDDEDSHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTAREAKVLRMRFGID
                     MNTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSEVLRSFLDD"
     gene            complement(38686..40431)
                     /gene="dnaG"
                     /locus_tag="RHX21_000933"
     CDS             complement(38686..40431)
                     /gene="dnaG"
                     /locus_tag="RHX21_000933"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDV1986158.1"
                     /translation="MAGRIPRVFINDLLARTDIVDLIDARVKLKKQGKNFHACCPFHN
                     EKTPSFTVNGEKQFYHCFGCGAHGNAIDFLMNYDKLEFVETVEELAAMHNLEVPFEAG
                     SGPSQIERHQRQTLYQLMDGLNTFYQQSLQQPVATSARQYLEKRGLSHEVIARFAIGF
                     APPGWDNVLKRFGGNPENRQSLIDAGMLVTNDQGRSYDRFRERVMFPIRDKRGRVIGF
                     GGRVLGNDTPKYLNSPETDIFHKGRQLYGLYEAQQDNAEPNRLLVVEGYMDVVALAQY
                     GINYAVASLGTSTTADHIQLLFRATNNVICCYDGDRAGRDAAWRALETALPYMTDGRQ
                     LRFMFLPDGEDPDTLVRKEGKEAFEARMEQAMPLSAFLFNSLMPQVDLSTPDGRARLS
                     TLALPLISQVPGETLRIYLRQELGNKLGILDDSQLERLMPKAAESGVSRPVPQLKRTT
                     MRILIGLLVQNPELATLVPPLENLDENKLPGLGLFRELVNTCLSQPGLTTGQLLEHYR
                     GTNNAATLEKLSMWDDIADKNIAEQTFTDSLNHMFDSLLELRQEELIARERTHGLSNE
                     ERLELWTLNQELAKK"
     gene            complement(40542..40757)
                     /gene="rpsU"
                     /locus_tag="RHX21_000934"
     CDS             complement(40542..40757)
                     /gene="rpsU"
                     /locus_tag="RHX21_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HDV1986159.1"
                     /translation="MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTE
                     RKRAKASAVKRHAKKLARENARRTRLY"
     gene            40994..42007
                     /gene="tsaD"
                     /locus_tag="RHX21_000935"
     CDS             40994..42007
                     /gene="tsaD"
                     /locus_tag="RHX21_000935"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001264383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HDV1986160.1"
                     /translation="MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVP
                     ELASRDHVRKTVPLIQAALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAW
                     NVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDD
                     AAGEAFDKTAKLLGLDYPGGPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFA
                     ANTIRDDGTDDQTRADIARAFEDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLR
                     AKLAEMMKKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGATADLGVSVRPRWPLAEL
                     PAA"
     gene            complement(42050..43513)
                     /gene="ttdT"
                     /locus_tag="RHX21_000936"
     CDS             complement(42050..43513)
                     /gene="ttdT"
                     /locus_tag="RHX21_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-tartrate/succinate antiporter"
                     /protein_id="HDV1986161.1"
                     /translation="MKPSTEWWRYLAPLAVIAIIALLPVPAGLENHTWLYFAVFTGVI
                     VGLILEPVPGAVVAMVGISIIAILSPWLLFSPEQLAQPGFKFTAKSLSWAVSGFSNSV
                     IWLIFAAFMFGTGYEKTGLGRRIALFLVKKMGHRTLFLGYAVMFSELILAPVTPSNSA
                     RGAGIIYPIIRNLPPLYQSQPNDSSSRSIGSYIMWMGIVADCVTSAIFLTAMAPNLLL
                     IGLMKSASHATLSWGDWFLGMLPLSILLVLLVPWLAYVLYPPVLKSGDQVPRWAETEL
                     QAMGPLCSREKRMLGLMVGALVLWIFGGDYIDAAMVGYSVVALMLLLRIISWDDIVSN
                     KAAWNVFFWLASLITLATGLNNTGFISWFGKLLAGSLSGYSPTMVMVALIVVFYLLRY
                     FFASATAYTSALAPMMIAAALAMPEIPLPVFCLMVGAAIGLGSILTPYATGPSPIYYG
                     SGYLPTVDYWRLGAIFGLIFLVLLVITGLLWMPVVLL"
     gene            complement(43561..44166)
                     /gene="ttdB"
                     /locus_tag="RHX21_000937"
     CDS             complement(43561..44166)
                     /gene="ttdB"
                     /locus_tag="RHX21_000937"
                     /EC_number="4.2.1.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L(+)-tartrate dehydratase subunit beta"
                     /protein_id="HDV1986162.1"
                     /translation="MKKILTTPIKAEDLQDIRVGDVIYLTGTLVTCRDVCHRRLIELK
                     RPIPYDLNGKAIFHAGPIVRKNGDKWEMVSVGPTTSMRMESFEREFIEQTGVKLVVGK
                     GGMGPLTEEGCQKFKALHVIFPAGCAVLAATQVEEIEEVHWTELGMPESLWVCRVKEF
                     GPLIVSIDTHGNNLIAENKKLFAERRDPIVEEICEHVHYIK"
     gene            complement(44163..45074)
                     /gene="ttdA"
                     /locus_tag="RHX21_000938"
     CDS             complement(44163..45074)
                     /gene="ttdA"
                     /locus_tag="RHX21_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L(+)-tartrate dehydratase subunit alpha"
                     /protein_id="HDV1986163.1"
                     /translation="MMSESNKQQAVNKLTEIVANFTAMISTRMPDDVVDKLKQLKDAE
                     TSSMGKIIYHTMFDNMQKAIDLNRPACQDTGEIMFFVKVGSRFPLLGELQSILKQAVE
                     EATVKAPLRHNAVEIFDEVNTGKNTGSGVPWVTWDIIPDNDDAEIEVYMAGGGCTLPG
                     RSKVLMPSEGYEGVVKFVFENISTLAVNACPPVLVGVGIATSVETAAVLSRKAILRPI
                     GSRHPNPKAAELELRLEEGLNRLGIGPQGLTGNSSVMGVHIESAARHPSTIGVAVSTG
                     CWAHRRGTLLVHADLTFENLSHTRSAL"
     gene            45281..46213
                     /gene="ttdR"
                     /locus_tag="RHX21_000939"
                     /gene_synonym="dan"
     CDS             45281..46213
                     /gene="ttdR"
                     /locus_tag="RHX21_000939"
                     /gene_synonym="dan"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator TtdR"
                     /protein_id="HDV1986164.1"
                     /translation="MLNSWPLAKDLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQIL
                     ENTLATTLLNRSARGVALTESGQRCYEHALEILTQYQRLVDDVTQIKTRPEGMIRIGC
                     SFGFGRSHIAPAITELMRNYPELQVHFELFDRQIDLVQDNIDLDIRINDEIPDYYIAH
                     LLTKNKRILCAAPEYLQKYPQPQSLQELSRHDCLVTKERDMTHGIWELGNGQEKKSVK
                     VSGHLSSNSGEIVLQWALEGKGIMLRSEWDMLPFLESGKLVQVLPEYAQSANIWAVYR
                     EPLYRSMKLRVCVEFLAAWCQQRLGKPDEGYQVM"
     gene            complement(46226..46843)
                     /gene="plsY"
                     /locus_tag="RHX21_000940"
     CDS             complement(46226..46843)
                     /gene="plsY"
                     /locus_tag="RHX21_000940"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HDV1986165.1"
                     /translation="MSAIAPGMILIAYLCGSISSAILVCRLCGLPDPRTSGSGNPGAT
                     NVLRIGGKGAAVAVLIFDVLKGMLPVWGAYELGVSPFWLGLIAIAACLGHIWPVFFGF
                     KGGKGVATAFGAIAPIGWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKP
                     QFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKFKRKREKDPE"
     gene            46948..47316
                     /gene="folB"
                     /locus_tag="RHX21_000941"
     CDS             46948..47316
                     /gene="folB"
                     /locus_tag="RHX21_000941"
                     /EC_number="4.1.2.25"
                     /EC_number="5.1.99.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708868.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional dihydroneopterin
                     aldolase/7,8-dihydroneopterin epimerase"
                     /protein_id="HDV1986166.1"
                     /translation="MDIVFIEQLSVITTIGVYDWEQTIEQKLVFDIEMAWDNRKAAKS
                     DDVADCLSYADIAETVVSHVEGARFALVERVAEEVAELLLARFNSPWVRIKLSKPGAV
                     ARAANVGVIIERGNNLKENN"
     gene            47406..48227
                     /gene="bacA"
                     /locus_tag="RHX21_000942"
     CDS             47406..48227
                     /gene="bacA"
                     /locus_tag="RHX21_000942"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708867.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDV1986167.1"
                     /translation="MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDT
                     AKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGESKGRLTLIHILLGMIPA
                     VVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMI
                     GCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGF
                     LTTGDIPMFAVGFITAFVVALIAIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF"
     gene            complement(48390..49628)
                     /gene="cca"
                     /locus_tag="RHX21_000943"
     CDS             complement(48390..49628)
                     /gene="cca"
                     /locus_tag="RHX21_000943"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused tRNA nucleotidyltransferase/2',3'-cyclic
                     phosphodiesterase/2' nucleotidase/phosphatase Cca"
                     /protein_id="HDV1986168.1"
                     /translation="MKIYLVGGAVRDALLGLPVKDRDWVVVGSTPQEMLDAGYQQVGR
                     DFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEDDLKRRDLTINALAQDD
                     NGEIIDPYNGLGDLQNRLLRHVSPAFGEDPLRVLRVARFAARYAHLGFRIADETLTLM
                     REMTHAGELEHLTPERVWKETESALTTRNPQVFFQVLRDCGALRVLFPEIDALFGVPA
                     PARWHPEIDTGIHTLMTLSMAAMLSPQVDVRFATLCHDLGKGLTPPELWPRHHGHGPA
                     GVKLVEQLCQRLRVPNEIRDLARLVAEFHDLIHTFPMLNPKTIVKLFDSIDAWRKPQR
                     VEQLALTSEADVRGRTGFESADYPQGRWLREAWEVAQSVPTKAVVEAGFKGVEIREEL
                     TRRRIAAIASWKEQRCPKPD"
     gene            complement(49692..50312)
                     /locus_tag="RHX21_000944"
     CDS             complement(49692..50312)
                     /locus_tag="RHX21_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HDV1986169.1"
                     /translation="MPKLRLIGLTLLALSATAVSHAEETRYVSDELNTWVRSGPGDHY
                     RLVGTVNAGEEVTLLQTDANTNYAQVKDSSGRTAWIPLKQLSTEPSLRSRVPDLENQV
                     KTLTDKLTNIDNTWNQRTAEMQQKVAQSDSVINGLKEENQKLKNELIVAQKKVDAASV
                     QLDDKQRTIIMQWFMYGGGVLGLGLLLGLVLPHLIPTRKRKDRWMN"
     gene            50554..51855
                     /gene="ygiF"
                     /locus_tag="RHX21_000945"
     CDS             50554..51855
                     /gene="ygiF"
                     /locus_tag="RHX21_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic triphosphatase"
                     /protein_id="HDV1986170.1"
                     /translation="MAQEIELKFIVNHSAVEALRDHLNTLGGEHHDPVQLLNIYYETP
                     DNWLRGHDMGLRIRGENGRYEMTMKVAGRVTGGLHQRPEYNVALSEPTLDLAQLPTEV
                     WPNGELPADLASRVQPLFSTDFYREKWLVAVDDSRIEIALDQGEVKAGEFAEPICELE
                     LELLSGDTRAVLKLANQLVSQTGLRQGSLSKAARGYHLAQGNPAREIKPTTILHVAAK
                     ADVEQGLEAAFELALAQWQYHEELWVRGNDAAKEQVLAAIGLVRHALMLFGGIVPRKA
                     STHLRDLLTQCEATIASAVSAVTAVYSTETAMAKLALTEWLVSKAWQPFLDAKAQGKI
                     SDSFKRFADIHLSRHAAELKSVFCQPLGDRYHDQLPRLTRDIDSILLLAGYYDPVVAQ
                     AWLENWQGLRHAIATGQRIEIEHFRNEANNQEPFWLHSGKR"
     gene            51878..54718
                     /gene="glnE"
                     /locus_tag="RHX21_000946"
     CDS             51878..54718
                     /gene="glnE"
                     /locus_tag="RHX21_000946"
                     /EC_number="2.7.7.42"
                     /EC_number="2.7.7.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional [glutamate--ammonia
                     ligase]-adenylyl-L-tyrosine
                     phosphorylase/[glutamate--ammonia-ligase]
                     adenylyltransferase"
                     /protein_id="HDV1986171.1"
                     /translation="MKPLSSPLQQYWQTVVERLPEPLAEESLSAQAKSVLTFSDFVQD
                     SVIVHPEWLTELESQPPQADEWQHYAAWLQEALSNVSDEVGLMRELRLFRRRIMVRIA
                     WAQTLALITEESILQQLSHLAETLIVAARDWLYDACCREWGTPCNAQGEAQPLLILGM
                     GKLGGGELNFSSDIDLIFAWPEHGCTQGGRRELDNAQFFTRMGQRLIKVLDQPTQDGF
                     VYRVDMRLRPFGESGPLVLSFAALEDYYQEQGRDWERYAMVKARIMGDSEGVYANELR
                     AMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLTDNIKLGAGGIREIEFIVQVFQ
                     LIRGGREPSLQSRSLLPTLSVIAALHLLSENDAEQLRVAYLFLRRLENLLQSINDEQT
                     QTLPSDELNRARLAWAMDFADWPQLTGALTAHMTNVRRVFNELIGDDESETQEESLSE
                     QWRELWQDALQEDDTTPVLAHLSEDDRKQVLTLIADFRKELDKRTIGPRGRQVLDHLM
                     PHLLSDVCAREDAAVTLSRITALLVGIVTRTTYLELLSEFPAALKHLISLCAASPMIA
                     SQLARYPLLLDELLDPNTLYQPTATDAYRDELRQYLLRVPEDDEEQQLEALRQFKQAQ
                     LLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWVQMVARYGKPNHLNDREGRG
                     FAVVGYGKLGGWELGYSSDLDLIFLHDCPMDAMTDGEREIDGRQFYLRLAQRIMHLFS
                     TRTSSGILYEVDARLRPSGAAGMLVTSAEAFADYQKNEAWTWEHQALVRARVVYGDPQ
                     LTAHFDAVRREIMTLPREGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIE
                     FITQYLVLRYAHEKPKLTRWSDNVRILELLAQNDIMEEQEAMALTRAYTTLRDELHHL
                     ALQELPGHVPEDCFTAERELVRASWQKWLVEE"
     gene            54766..56199
                     /gene="hldE"
                     /locus_tag="RHX21_000947"
     CDS             54766..56199
                     /gene="hldE"
                     /locus_tag="RHX21_000947"
                     /EC_number="2.7.1.167"
                     /EC_number="2.7.7.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     D-glycero-beta-D-manno-heptose-7-phosphate
                     kinase/D-glycero-beta-D-manno-heptose 1-phosphate
                     adenylyltransferase HldE"
                     /protein_id="HDV1986172.1"
                     /translation="MKVTLPEFERAGVMVVGDVMLDRYWYGPTSRISPEAPVPVVKVN
                     TIEERPGGAANVAMNIASLGANARLVGLTGIDDAARALSKSLADVNVKCDFVSVPTHP
                     TITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALSSIGALVLSDYAKGALASV
                     QQMIQLARKAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVVGKCKTEEEIVERGMK
                     LIADYELSALLVTRSEQGMSLLQPGKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAA
                     GNSLEEACFFANAAAGVVVGKLGTSTVSPIELENAVRGRADTGFGVMTEEELKLAVAA
                     ARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGDSRPVNP
                     LEQRMIVLGALEAVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSKEVWANG
                     GEVLVLNFEDGCSTTNIIKKIQQDKKG"
     gene            complement(56319..56378)
                     /gene="ibsE"
                     /locus_tag="RHX21_000948"
     CDS             complement(56319..56378)
                     /gene="ibsE"
                     /locus_tag="RHX21_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin IbsE"
                     /protein_id="HDV1986173.1"
                     /translation="MMKFVIILVVLLLLSFPTY"
     gene            complement(56695..56754)
                     /locus_tag="RHX21_000949"
     CDS             complement(56695..56754)
                     /locus_tag="RHX21_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HDV1986174.1"
                     /translation="MMKLVIILIVLLLVSFAAY"
     gene            complement(56993..58654)
                     /locus_tag="RHX21_000950"
     CDS             complement(56993..58654)
                     /locus_tag="RHX21_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HDV1986175.1"
                     /translation="MDDIVNSVPSWMFTAIIAVCILFIIGIIFARLYRRASAEQAFVR
                     TGLGGQKVVMSGGAIVMPIFHEIIPINMNTLKLEVSRSTIDSLITKDRMRVDVVVAFF
                     VRVKPSVEGIATAAQTLGQRTLSPEDLRMLVEDKFVDALRATAAQMTMHELQDTRENF
                     VQGVQNTVAEDLSKNGLELESVSLTNFNQTSKEHFNPNNAFDAEGLTKLTQETERRRR
                     ERNEVEQDVEVAVREKNRDALSRKLEIEQQEAFMTLEQEQQVKTRTAEQNARIAAFEA
                     ERRREAEQTRILAERQIQETEIEREQAVRSRKVEAEREVRIKEIEQQQVTEIANQTKS
                     IAIAAKSEQQSQAEARANLALAEAVSAQQNVETTRQTAEADRAKQVALIAAAQDAETK
                     AVELTVRAKAEKEAAEMQAAAIVELAEATRKKGLAEAEAQRALNDAINVLSDEQTSLK
                     FKLALLQALPAVIEKSVEPMKSIDGIKIIQVDGLNRGSAAGDANTGNVGGGNLAEQAL
                     SAALSYRTQAPLIDSLLNEIGVSGGSLAALTSPLTSTTPVAENVE"
     gene            complement(58681..59310)
                     /locus_tag="RHX21_000951"
     CDS             complement(58681..59310)
                     /locus_tag="RHX21_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1449 family protein"
                     /protein_id="HDV1986176.1"
                     /translation="MILFADYNTPYLFAISFVLLIGLLEILALICGHMLSGALDAHLD
                     HYDSITTGHISQALHYLNIGRLPALVVLCLLAGFFGLIGILLQHACIMVWQSPLSNLF
                     VVPVSLLFTIIAVHYTGKIVAPWIPRDHSSAITEEEYIGSMALITGHQATSGNPCEGK
                     LTDQFGQIHYLLLEPEEGKFFTKGDKVLIICRLSATRYLAENNPWPQIL"
     gene            59579..59779
                     /gene="glgS"
                     /locus_tag="RHX21_000952"
     CDS             59579..59779
                     /gene="glgS"
                     /locus_tag="RHX21_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface composition regulator GlgS"
                     /protein_id="HDV1986177.1"
                     /translation="MDHSLNSLNNFDFLARSFARMHAEGRPVDILAVTGNMDEEHRTW
                     FCARYAWYCQQMMQARELELEH"
     gene            complement(59822..60823)
                     /locus_tag="RHX21_000953"
     CDS             complement(59822..60823)
                     /locus_tag="RHX21_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001426899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986178.1"
                     /translation="MDCYAEHEGGNTVVIGYVPRISIPSNGKKGDKIWQSSEYFMNVF
                     CNNALPAPSPGEEYPSAWTNIMMFLPGGQDFYNQNSYIFGVTYNGVDYDSTAPNAIAA
                     PECIDIKGAGTFNNHYKNPAVCSGGPEPQLSVTFPARVQLYIKLAKNANRVNKNLVLP
                     DEYIALEFKGMSGAGAIEVDKNLTFRIRGLNNIHVLDCFVNVALEPADGVVDFGKINS
                     RTIKNTSVSETFSVVMTKDPGAACTEQFNILGSFFTTDILSDYSHLDMGNGLLLKIFH
                     KDGTATEINRFSQFASFSSSSAPSVTAPFRAELSANPAETVVEGPFSKDVILKITYN"
BASE COUNT        14674 a        15420 c        16102 g        14652 t
ORIGIN      
        1 aactttttgg aaacaatatt gtaagatcaa atttatatgg tggcgaaaat taatctctta
       61 tcacggctta cgccgctttt attcgtgttc gctccttttt tggcacagtc aaatatgact
      121 gtttatccta tggctgtttc cattaatagt cagggtgaag gcaacgttcg cgtaatatct
      181 aaaagtaatg aagttcagta catcaaggcg acagtattcc gtatcgataa tccatcgacg
      241 cctcaggaaa atgaagttga gattaaatcc ggtgatgcaa atcatctggt tgttatgcca
      301 cctaaattcg ctttaccagc cggtagtagc aaaaccgtac gttttgttgc gatggaacca
      361 gagcaaaaag agaaaaatta tcgcgttaaa tttgaagcgg ttcccagtat tgatgacgtt
      421 gccacagata aaaaagatct ctctatgcag ttaacagtta acttaatttg ggggattgtt
      481 gttagtgttc cacctcagca acctattgct aagttagaag taaatgctgc ccaaaaatta
      541 gttaatgcag ggaatcaacg cttaaagatt ttaacgatcg cttattgtaa aaataatagc
      601 aaagaaaatt gtaagataca gaccgtaaat aaaaacatct tccctggtca ggaaagaaat
      661 cttgaaagca tatctggcta cgacaaaatc gttgtcaaat ataataactg gatcaccaaa
      721 gataatggcg agtttgaact ggcggtccat taattatcat tgtaataaac gaaggaatag
      781 taatgaaaaa ggtatttgca aaatctcttc tggtcgcagc gatgttttct gttgcaggct
      841 ccgcattggc agtacaaaag gatattactg taacggccaa cgttgatgcc gctctggata
      901 tgacacagac cgataacacc gcgttgccga aagcagtaga aatgcaatat ctgccggggc
      961 agggtctgca atcttaccag ttgatgacca aaatctggtc taacgacgtt accaaagatg
     1021 taaaaatgca gttagtttcc ccggcgcaac tggttcaaag cctggatgct agcaagattg
     1081 ttccgctgac agtaacctgg ggcggtgaag aaattaaagc tgatgcggca accactttta
     1141 ccgcaaccaa aatctttgct tccgatgcgt taactaacgg ttctctggct aaaaacctga
     1201 tgtttgctca aaccaccaaa ggtgttctgg agacaggcat ctaccgtggt gtagtaagca
     1261 tttatctgtc tcaggatatc taatccagat aacagaatta acacgtaaca aagggagggg
     1321 tagccctccc ttattttaac tgttttagta tttgttatgg atttcaggat tgccatggat
     1381 aaaaaattac tggctctttt gatcctggcg agtctcagcc cggcagaggc gacattaacc
     1441 aaaattcccg cagggtttga ggttattgct cagggacagc aggagtatat cgaggtttat
     1501 ttttcaggga aaagtctcgg taaatattat gcaatggtta atcttgatac cgtaacattt
     1561 cttgatccag caagtctata taacaagctg gaactggatg tagacgatca gaaaatcgcg
     1621 catatagtga aagaaaaatt atcgcagccg ctagctcgcc acggtgaatt ggcttgcggt
     1681 tatgtacgta ctgactcagg gtgtggtttt ctgaataccg atacgctgga aataatctat
     1741 aatgatgaag aaagttcggc aacgttgttt attaatccgc aatggaattc agctttcgat
     1801 gcgaagtcat tatatttaaa tccagacaaa aatactgtta atgcttttat acatcagcaa
     1861 gacatcaatg ttctggcaca ggatgattac caatcgttgt ctattcaggg aaacggtgcg
     1921 ctgggaataa cagaaaatag ttatattggt gcacactgga atttcaacgg ttatgatgca
     1981 gatgatgtca gtgacagtaa tgctgacgtc agcgatctct attatcgtta tgatttttta
     2041 cgtcgttatt atgtgcaggc gggtcgcatg gacaaccgca cactatttaa tgcacaaggc
     2101 gggaacttta cctttaactt tctgccactc ggtgcaattg atgggatgcg tatcgggtcg
     2161 acactgagct atttaaacca ggcgcaaagc cagcaaggaa ccccagtaat ggttctgctt
     2221 tcgcgcaatt ctcgtgttga cgcttatcgt aatgagcaac ttttgggatc gttttatctc
     2281 aatagtggtt cgcaatttat tgataccagt tcctttccgc ctggcagcta cagcgtggca
     2341 ttaaaagtct acgaaaataa ccaactcacc cgcaccgagc ttgtgccgtt taccaaaacc
     2401 ggcggtctga ctgacggaaa tgcgcaatgg ttcttacagg caggtaaaac tacatcacag
     2461 gtttctgatg atgaaagttc agcttatcag ctaggagtac gcctgccatt acatccgcaa
     2521 tatgagctct acgcagggct ggcgaatgcc gatgatgtga gtgctttcga gttaggtaat
     2581 aactggacgg cagatttagg cggggtgggg aatcttgcaa tcagcgccag cgtgttccgt
     2641 aacgatgacg gcggcaaagg tgatatgcaa caggccaact ggagtaatcc gggatggccg
     2701 acgttgggct tttatcggac caactctgac ggcgatgctt gtacaaccga cagcagagag
     2761 agctataacg ccttaagctg ttatgaaagt atttccgcga cggtttcaca gaattttgtc
     2821 ggctggaata tgatgctggg ttatacccgc acacaaaata acactgatga tagtttgcgt
     2881 tgggataaac agcagagctt tgaaaataac tatcttcgcc agacaacagc gcaaagtatc
     2941 tctgaaactg tacaacttag cgcttcccgc gcttttgtga tgcgtgactg gattttgagt
     3001 acgtcagtcg gtgttttcca tcgtaatgac aacggtggcg ataacgacga caacggcttg
     3061 tacttatcgt tttcgttatc tgacacgcca acgatggata gcaataacaa cagccattca
     3121 acaaatgtgt ctacggatta tcgttatagc gaacaggatg gcgatcaaac gtcatggcag
     3181 ttatcgcata ccttttataa cgattcattc agccataaag aacttggcgt aaccgtcgga
     3241 ggcctgaaca ccgataccat aaacagcgcg gttaacgggc gttgggatgg gcaatacgga
     3301 aatgtctacg ctaccgtatc tgatagttat gaccgtaaga atcatgatca tctttcggcc
     3361 tttacgggca cttatagctc tacgctggct gtcagtcgct atggcgttaa tttgggagcc
     3421 agtggtacag acgatttgct gggtgcggta ctggtggatg tgaaaggctt ctctgaacag
     3481 gatgaagaga gtcaggatct gcaactcgaa gcgcgggtgg caggcagccg aactttgcag
     3541 cttggtcaaa gtgacagtgt gttgttccct tatcctggat ttcagtctgg ttttgttgag
     3601 gttaacgaca gtagccaggg caatcagcag gggacaacaa acatcattaa cggtgcaggg
     3661 aatcgtgaat taatgttgtt gcctggcaag ctgcgctatc gcgaagtgtc tgccagcttt
     3721 aactacaact atatcggtcg tttattactg ccggcagcgg tgaaaaaatt cccgattgtg
     3781 gggctgaaca gcgccatgtt actggtagct gaagatggcg gatttacact tgaaattaac
     3841 ggcagcgaaa aagagctcta tctgctttcc gggcagcaat tccttaagtg tccactgagt
     3901 gttgtaaaga aacgcgccag cattcgttac agcggagatg ttacttgtag tgtggtgact
     3961 tattcacaat taccggagtc gattcaggtt caggcacagt tgaaacagcc taaattacgt
     4021 ggaaacgttc agacggcgca aagggaggtt gcaccatgag aaatcgattg attgcagcga
     4081 tattgggctt gtttggcacg ctcactggcg ttcaggcagc tcctgacgtg accagtgaaa
     4141 ttacgtatga tttggcatct ggtagagcgg attattactt ctggaaggat gaagcgtcgg
     4201 caggaaataa tggatatatg tggtatgaat gttcgtatcc tgacctccaa caaacctgta
     4261 cagctaatgg aaatatatcg acagtacaaa tctatttaac tgaacaacgc agtgggatgc
     4321 gttggccggt aaaactcaaa ggatttaaaa cagccattgt aagtagcgat gaagcgccgc
     4381 caggatgcaa ggggggcaaa gggcttcaga cgaatcttaa ggattctaat agatcttcat
     4441 gtacagaaga tggtcaacat tattatatat acgatacaaa gtttcttacg ctctaccttg
     4501 agcagacaga gatgaagaat ttgccgattg gtggcgtctg gaaggggaaa gttaaattac
     4561 attcgaacag cccggcccag gactatttcg caaatattac cctgaatacg ctcgacccca
     4621 accatattga cgtgttcttc ccggagttcg cccacgccac gccaagggtg cagttagact
     4681 tgcatccaac aggaagcgtt aacggcagca actacgcgca agatctgacc atgttggaca
     4741 tgtgcctgta cgatggtttt aacggtaatg ccatcagtta tgaaatcatg ctcaaagatg
     4801 aagggcgacc agctgcaggg cgcagagacg gttacttctc tatctatcgt cagggaggga
     4861 ccaccaccga cgagggagaa cgcattgatt accgggtcaa aatgtacaac ccggaaaccg
     4921 gtgggcaaat tgatgtgcgc aataatgaaa atatggtctg gaacagcatt aacctgaaac
     4981 gtgtgcgtcc ggtggtactg cccggtattc gctatgccgt gatgtgtgtg ccgacaccct
     5041 tgactctggc agtcgataaa ttcagcgtga tggataaaca ggccgggtac tacatgggca
     5101 aattgtcagt aatctttacg ccttccttgc caaccatcaa ttaaccctgc aaaccggaca
     5161 aacgcttttt tctatataaa cgacgaagcc gtctgataag gcggcttcgt cattacaact
     5221 taagttaaac gttaatgttg cggtgcggga tcgttatgtg tttcctgcgc cacctcaatc
     5281 gccggtttgt tctgcaacac ggtccagata accagcgcac ccagcaggtc aaatactgcc
     5341 agaactgcga acagcgggct gaagccgatg gtgtcagcca gtgcaccgac aaccagcgca
     5401 aacagcgtac ttgccagcca tgcggacatc ccggttaaac cgttcgccgt cgccacttcg
     5461 ttacgaccga acacgtcaga agagagcgta atcagcgcgc cagacagtgc ctggtgggca
     5521 aaaccaccga tacacagcag cataattgcg acatacgggt tggtgaacag accgatcata
     5581 cccgggccaa tcatcagcac agcacccagc gttacgacca tcttacggga aacgatcagg
     5641 ttcacaccaa accaacgctg gaacagcggc ggcaggtaac caccgaggat acaaccgagg
     5701 tcagcaaaca gcatcggcat ccaggcgaac atcgcgatct ctttcaggtt aaagccgtaa
     5761 actttaaaca tgaacagcgg gatccacgcg ttaaaagtac cccaggccgg ttctgccagg
     5821 aaacgcggca gcgcgatacc ccagaactga cggttacgca ggatctgacc aacggacatt
     5881 ttcttcgccg tgctcacctg gtgctgggct tcctgaccat taataatata gtcgcgttct
     5941 tcatcggtca gatgcttctg gtcgcgtgga tgtttataga aaatcagcca tgccatcgcc
     6001 cagataaagc tcaatgcacc ggagatgata aatgccatct gccagctgtg cattacgatt
     6061 gcccatacca ccagcggcgg cgcaatcatc gcaccaatcg aagaacctac gttaaagtaa
     6121 cctaccgcga tggaacgctc tttcgccgga aaccattcgg agctggcttt cagacccgcc
     6181 gggatcatcg ctgcttccgc ggcaccgact gcaccacgag caatcgccag gccaccccag
     6241 ctaccagcca gcgcggttgc accacagaac acggcccaca gcacagcaaa cattgcataa
     6301 ccgattttcg tacccagcac atccagtaca taacctgcta ccggttgcat gaccgtataa
     6361 gcagcagaat aggctgcgat gatataggaa tactgttggg tggagatgtt taactcttcc
     6421 atcagagttg gcgcagctgc cgccacagtg ttacgcgtca ggtaaccaag cacggtgccg
     6481 agcgtcacca gtgcgatcat ataccaacgt aaccctttaa ttttacgcat gtaaaacctc
     6541 atcgttttgt tatatccgca ggaagcgcgg ccatcatccc gccagaggct gaagatgtta
     6601 gttacgaccg ggtaaccgaa aaaaaaccgg cacgccccga acgttgccat gaaagtttcg
     6661 tgctaattcg gcttccgtac cggttaaccc gattcatcta acaaatgaat gaatcggcaa
     6721 tttgcattcc gtcgacttat gatttgcgac ggcagaaaga taacttgtca tacaacttta
     6781 aaaggtgaga gccatcacaa atgtgcgaat atttgtaggg acattacctg acgacagcga
     6841 ggccagtact ggcgcggcct gcagagagat ttaccacttt gagagtaatt tttttaacta
     6901 cgtttattga tctaactcac gaaaatatct tcggactctg gaaattggtg tgataacttt
     6961 gtcagcatcg caccataagc aagctagctc actcgttgag aggaagacga aaatgactcc
     7021 gtttatgact gaagatttcc tgttagatac cgaatttgcc cgccgtctgt atcacgacta
     7081 cgcaaaagac cagccgattt tcgattacca ttgccatttg ccgccgcagc agattgcgga
     7141 agactatcgt tttaaaaacc tgtatgacat ctggctgaaa ggcgatcact acaaatggcg
     7201 cgctatgcgt accaacggtg tggccgagcg tctgtgtacc ggtgatgcgt ctgaccgtga
     7261 aaaatttgac gcctgggcgg cgactgttcc gcacactatc ggcaacccgt tataccactg
     7321 gacgcacctc gaactgcgtc gtccgtttgg tatcactggc aaattgcttt ctccgtcaac
     7381 tgccgatgaa atctggaacg aatgtaacga actgctggcg caggataact tctccgcgcg
     7441 cggcatcatg cagcagatga acgtgaaaat ggtcggcacc accgatgacc cgatcgattc
     7501 tctggagcat cacgcagaga tcgccaaaga cggctctttc accatcaaag tgctgccgag
     7561 ctggcgtccg gacaaagcct tcaacatcga acaggcgacc tttaacgact acatggcgaa
     7621 gctgggcgaa gtttccgata ccgacattcg ccgctttgct gacctgcaaa ctgccttgac
     7681 caaacgtctg gatcacttcg ccgctcacgg ctgtaaagtg tctgaccatg cgctggacgt
     7741 ggtgatgttt gctgaagcga acgaagcgga actggacagc attctggcgc gccgtctggc
     7801 tggcgaaccc ctgagcgagc acgaagtggc acagttcaaa actgcggtac tggtgttcct
     7861 tggtgccgaa tatgcacgtc gcggctgggt acagcagtac cacattggcg cgctgcgtaa
     7921 taacaacctg cgtcagttca aactgctggg gccggatgta ggctttgact ccatcaacga
     7981 ccgtccgatg gcggaagagt tgtctaagct gctgagcaag cagaacgaag aaaacctgct
     8041 gccgaaaacc attctctact gcctgaaccc gcgcgataac gaagtgctgg gcaccatgat
     8101 cggtaacttc cagggcgaag gtatgccggg caaaatgcag ttcggttccg gctggtggtt
     8161 taacgatcag aaagacggta tggaacgtca gatgacccaa ctggcgcagc tcggtctgct
     8221 gagccgcttt gtcggtatgc tgactgacag ccgtagcttc ctgtcataca cccgtcacga
     8281 atacttccgc cgcattctgt gccagatgat cggtcgctgg gtggaagcgg gcgaagcacc
     8341 ggcggacatc aacctgctgg gcgagatggt gaaaaatatt tgctttaaca atgcgcgtga
     8401 ctacttcgcc attgaactga actaaggtct ggggttgata tgcaatacat caagatccat
     8461 gcgctggata acgtcgcggt cgctttagca gatttggctg aaggcacaga agtcagtgtc
     8521 gataaccaga ctgttacgct gcgccaggat gttgctcgtg gacataaatt tgcgttaacg
     8581 gatatcgcaa aaggggccaa cgtcatcaaa tatggcctgc cgattggtta tgcattggcg
     8641 gatattgcgg cgggggaaca cgtccacgcc cacaatacgc gcacgaatct gagcgatctg
     8701 gatcagtatc gctatcaacc tgattttcag gatctgcctg cgcaagcggc agatcgtgaa
     8761 gtgcagatct atcgtcgcgc taacggcgat gtcggggtgc gtaatgagct gtggatcctg
     8821 ccaaccgtgg gctgtgtcaa cggcatcgcg cggcaaatcc agaaccgttt cctgaaagag
     8881 accaacaacg ccgaaggtac cgacggcgtg ttcctcttca gccacaccta cggctgctca
     8941 caactgggcg acgatcacat caacacccgc accatgctgc aaaacatggt gcgccacccg
     9001 aacgcgggcg cagtgctggt gattggtctg ggctgtgaaa acaaccaggt tgccgcattc
     9061 cgtgaaacgt tgggcgatat cgatcctgaa cgcgttcatt tcatgatctg ccaacagcag
     9121 gatgatgaga tcgaagccgg gatcgagcat ttgcatcagc tgtataacgt gatgcgcaac
     9181 gataaacgcg agccaggcaa actcagcgaa ctgaagtttg gtctggagtg cggtggttct
     9241 gacggtcttt ctggtattac tgctaacccg atgctggggc gtttctctga ctacgtgatt
     9301 gctaacggcg gtactaccgt actgaccgaa gtgccggaga tgtttggcgc agagcagttg
     9361 ctgatggacc attgccgcga cgaagcaacg tttgaaaaac tggtcaccat ggtcaacgac
     9421 ttcaaacagt actttattgc ccatgaccag ccgatctatg aaaacccatc gccggggaac
     9481 aaagcgggcg gtatcaccac gctggaagat aaatcccttg gctgtaccca gaaagcgggt
     9541 tccagcgtcg tggttgacgt gctgcgttac ggcgagcgtc tgaaaacgcc ggggctgaac
     9601 ttgttaagtg cgccgggtaa cgatgccgta gcgaccagcg ccctggcggg tgcgggctgc
     9661 catatggtgc tgttcagtac tggtcgtggc acgccatacg gcggctttgt accgacggtg
     9721 aaaatcgcta ccaacagtga actggcggcg aagaaaaaac actggatcga ctttgacgcg
     9781 ggtcagctga tccacggtaa agcgatgccg cagttgctgg aagaatttat cgacaccatc
     9841 gttgagtttg ccaacggtaa acaaacctgc aacgagcgta acgacttccg cgaactggcg
     9901 atcttcaaaa gcggcgtaac gctataaagt cgaaatgagt tgttaataaa aaacggcgtt
     9961 tcataatgtg aagcgccgtt tgcttttcca tacctgataa ggatttatca tgaccgcgta
    10021 ttggctggcc cagggcgtgg gtgtcatcgc ctttctgatt ggtatcacaa catttttcaa
    10081 tcgtgacgaa cgtcgcttca aaaagcagct ttcggtctat agcgccgtta ttggcgtaca
    10141 tttttttctt ctgggcacct atcccgctgg tgccagtgcc atccttaatg ccattcgtac
    10201 attgattacc ttacgcacgc gcagcttatg ggtaatggcg atttttattg tgctgactgg
    10261 cggaattggc ctcgcgaagt tccatcatcc tgtcgaacta ttgccggtta tcggtacgat
    10321 tgtcagtacc tgggcgctgt tccgctgtaa agggctcacc atgcgctgcg tgatgtggtt
    10381 ttcaacgtgt tgctgggtga ttcacaactt ctgggcgggg tcgataggcg gcacaatgat
    10441 tgagggtagt tttctgctta tgaatggctt gaatatcatt cgtttctggc ggatgcagaa
    10501 aaggggaatt gatccgttta aagtagagaa aacccctccc gccgtagacg aaaggggtta
    10561 aacaattaat tacgcagggc gctatttgcc agacgatcgt cttccgcctg gcaagctgcc
    10621 gcagtgaaca gcacgtcagt tgaagagttc agcgcggttt cgcaagagtc ctgcaatacg
    10681 ccgatgataa agccgacggc aaccacctgc atggcgatat cgttcgaaat accgaacata
    10741 ttacaggcca gcgggatcag cagcagagaa ccccccgcca cgccggatgc gccacaggca
    10801 cacagagaag ccaccacgct caacagcagc gccgtgggca gatcgaccgg gatacccagc
    10861 gtattaaccg cagccagcgt caacacggta atggtgattg ctgcgcccgc catattgatg
    10921 gtggcaccca gcggaataga aacggaatag gtatcgcgat ccagattcag cttttcacac
    10981 agtgccatat tcaccggaat gttcgccgca gagctgcggg tgaagaaggc atacacgccg
    11041 ctttcgcgca ggcacagcag caccagcggg aacgggttac gacgaatttt ccaccacacc
    11101 agcaatgggt taaccaccag cgccaccagt aacatacagc caaccagcac gaccagcagt
    11161 tgcgcgtagc cccacagtgt ggagaaaccg gtggttgcca gggtagaaga aaccagacca
    11221 aaaataccaa tcggtgcgaa gcgaatgacc agtttcacca taaaggtgac ggcattcgac
    11281 atatcgttga ccaggttttt ggtggtctcg ttaccgtgac gcagtgcgaa accgaggcca
    11341 attgcccaca ccaggatccc gatgtagtta cctttcagca gcgcgtcgat ggggttggaa
    11401 accatgctca ttaccagccc gcgcatcact tcgacaatgc ctgacggcgg cgaaatatca
    11461 cccgcgctac tggataaatg cagggtagaa gggaaggcaa agctgaagac tactgcggcc
    11521 agagcagcag agaaggtacc cagcagatag aggaacaaaa tagggcggat attggttttc
    11581 tgcccgtgct ggtggttagc aatagatgcc atcaccagca tcaacaccag gatgggggca
    11641 acggctttca gtgcgccgac gaacaaagta cctaacagac caacagcttc cgccgcgggt
    11701 tttgagatcc atgccagaag aatccccaga acaaggccga ccaggatttg ttttaccagg
    11761 ctgccatgag ccagacgccg gaatagcccc ggtgaacgtt gcgtagtcat ttttcgatcc
    11821 tttcattgtg ttgtcgcaca tccctggtgc gttctgtcga cgcatctttc aggatgtaac
    11881 aaagtgtttg caaggtcgag tataaggaaa gttacagctt cgggaagcga aaaatgctgg
    11941 attttaaaga gaggtcatat tttgcaactt aattgttaca tttgtttgac ataaacagag
    12001 ggaaggactg gctactaagg ctgattagat aacatatggg caaaactatt tggaatatga
    12061 gaacggttgc gctcctttaa tgtgttatgc catataaagt cactggcgca gggagcgcgc
    12121 agggggcggc caatcgccgc cgccccctgc acccccaggc tctggcgaac aaaatcgccg
    12181 ctgcgcggtt ccctcagctt atcccttgcg gctaccgggt cgggcgcaag gtaacgtccc
    12241 tgtaagatgc gccctcgccg cgcatccatg cgcgtcgccc cggcctccag ggaacgcttc
    12301 ggcgattttg acgccaccaa cacccgtgcg gtctttttgt aaagagctat aagccgatta
    12361 cataattaat agctcacctt tgtctggaat gagttatctc tagtaatggc ttaatataca
    12421 gcggatcatt ctccccgctg cttatcatgc cgataattca cccaggcgtt gataataaac
    12481 gtcatcacca gaatgccaaa caccacgccc agcgagacgg cgattggaat atggtagaag
    12541 tcgacaatca gcatcttgat accgataaac accagaatca ccgccaggcc atatttgagc
    12601 atcgagaaac gctctgctac gcccgccagc aggaaataca tcgcacgcag gccgaggatt
    12661 gcaaacaggt ttgaggtcag cacaataaac ggatcagtgg tcacggcgaa gatagccgga
    12721 atgctatcca cggcaaaaat cacgtcgctc aattccacca gaatcagtac cagcatcagc
    12781 ggtgtggcgt acagcaatcc attcttacgc acaaagaaat gctcgttgtc gatggtgtcg
    12841 gtcatgcgca aatgaccgcg tagccagcgc accagcggct tgtcgccaat gcctgattca
    12901 tcttcatggg cgagcgccat cttcacgccg gtaaacagca ggaaggcacc gaagatatac
    12961 aggatccagt cgaactgtga aatcagccag ctgcctgtga agatcatgat ggtacgcaga
    13021 acaatcgccc cgagcacgcc atacaccagc acgcggcgtt gtaatgccgc cggaacagag
    13081 aaatagctga acaacatcag ccagacaaag acgttatcga ccgccagcga tttctcaatc
    13141 agatagcccg tgagaaaggc cagtgcctgt ggatcggcaa cggcgcgacc ttcagtttgc
    13201 accagatacc accagaaagc ggcgttaaac agtaacgaca gcgtcaccca gaccagcgac
    13261 caggccgcag cctgtttcat ggtcatggca tgtgccccac gacgcccctg caacaacagg
    13321 tcgatagcca gcataatggc gacaacaaca gcgaatccgc cccatagcaa cggcgtgccg
    13381 acagtattca tagaagttcc ttacacataa aaaaacggcc aacgtcggaa gacgtcagcc
    13441 gctgcttttt atgcatagac ctcgccttcc ggcaaggtct cacttacaac aaaaaaggaa
    13501 tacgtctgcg tattcctttc gggttgcccg gtgaccggat gtggtttttc acacatcgta
    13561 atgacgatcg accggcaatg aagttactcc cctttgcagg taacaaagta tgacagacca
    13621 ttcagccagt caatggtctg ttacatacct tttacactgt tttactttgg caattatagt
    13681 tttacgctat ctgccggaaa aatcacccca gtctggcggc ggatctcggt cagcagtttg
    13741 gcggtgatgc gactgaccgc cagccccgga tgatccacca gatgctcatc caccagggta
    13801 gcgaacagct ctgcttcgta gagcatggta ttaatatgct gcggctgggt gagatcctgc
    13861 atttggctgc cacgcggcac gaagcacact ttctggcatt cagacagttt ttcaatcacc
    13921 agcgatcctg cttcgccctg aatctcgctc gccaggacag aatcactgac ttttgagtgc
    13981 tgcaaggtga cgctgaaatc accgtaatcc atcaccacca cgccgtgggc atctacaccg
    14041 cttgccagca aactggcggt tgcctgcacg cttttcggct caccaaataa cgccaccgcc
    14101 gacgccaggc agtaaaagcc gatatccata attgaaccgt tagagaatga cggattaaag
    14161 gtgttgggat tttcaccgtc caggtaacgt tgatagcgcg aggaatactg gcaatagttg
    14221 aaaaagactt tacgcaattt gccgactttc ggcagcgcct ggcgcagcaa atgaaagttc
    14281 ggcaggcagg cggttttaaa tgcctcaaac agcaccacct gattttcccg cgcacaggca
    14341 atggcggcat ccacttccgc cagattcgac gccagtggtt tctcgcaaat cacatgaatt
    14401 ttatggctaa ggaaaagttg tgtctgggaa aagtgcaggg cattcgggct ggcaatatac
    14461 accgcgtcaa tggcatcgct ttccgccatc gcttccagcg aggtaaacag atgctcgaca
    14521 gaaaaatcat tggcgaagtg ctgagcctgc tcaaggctgc gggaatatac ggcggttaac
    14581 ttgtatttac cgctctcatg ggcggcctcg acgaactggc gagtgatcca gttcgtacca
    14641 atcacagcga aacgtatcat aacgcgtgga tactccataa agggattctg tcgtcaatgt
    14701 agcacgcctt tttcatcttc gacgtgcgca gatacgcatt attcttttgc cggacagcca
    14761 tgctcactaa acggcccaat catgaccgat ggcccgagat atttcggctg gcgatggagg
    14821 attttggcgt caatcacggc gctgacacga gcgagtttct cccgcagttg agtataaaaa
    14881 ccgtgcttca tattgaggtc aggcgcgtta aaaccgatag cgtcgatgcc gtactgtttt
    14941 gccagccaga tggcgcgttg attatgaaat tcttgcgaga taatggtgat atggttttca
    15001 ccaaaaacct ttttggcacg cactaccgaa tccagcgttg agaatccggc atagtcgcag
    15061 aagatcactt tcgccggtac gcctttagcg atcaaagcct gctgcatacc tgaggcttca
    15121 tcgtaatttt tacgtccgtt atcgccactt accagtagcc atttcacttt tccggcgtgg
    15181 tacaacgctg ctgcggtatc aatacgtcgg gtaaagtagc gattacccgg cctggccccc
    15241 agcaataagc ccacgttacg cgccggaact gcgttgacat cgctccaggt cagctgcttg
    15301 ctggcgttga ccataacgcg atcggcaata aaaatggtcg ctcctgctat aagcaacaac
    15361 aaacagccaa tcttaagagt ccggcgagaa aaacaaatac ggagaagaag acggggctgc
    15421 atggtcgtta tccttaacga aaggggggag gtcgatttta ggcgctaaag aaagaaaaga
    15481 taacgcctga catcattttc agattttgtc ctgcccaagc gacaactgcg ttagccacag
    15541 ccgggtgtcg aactcaagct ggtggtactg cggctccata tggcagcaca actggtaaaa
    15601 cgctttgtta tgctctttct ccttcaggtg cgccagttcg tgcaccacga tcatacgtaa
    15661 aaacggttcc ggcgcgttgc gaaacacagt agcgacgcgg atctctgctt ttgctttcag
    15721 cttgccgccc tgcacacgag aaacagcggt atgtaacccg agcgcgtttt ttagcacatg
    15781 gatcttattg tcatacatca ctttattgat cggcggggca ttacgcagaa actgattttt
    15841 cagatcctga gtatattgcc agagggcttt atcggtggcg tagtcgtgtg ttcccggata
    15901 gcgttttgcc agcacatcgc ccagacgctg ttcgttaatc agcgttcgca cctgggaaag
    15961 tagctgctcg ggataaccct gaagataagt aagattgttc ataaccgccc acgaaaaaga
    16021 gaaaaagggt atactcacgc acccttttca ggggcaacgt cgaaatttta tcattcagga
    16081 gggccgatga gccacttaga caacggtttc cgttcactga cactacaacg ttttccggcg
    16141 acggatgacg ttaacccgct acaggcgtgg gaagcggcgg atgaatattt gctgcaacag
    16201 ttggacgaca cagaaatccg cggcccggtg ttgatcctga atgatgcctt tggtgcgtta
    16261 agctgcgcgc tggcggaaca taagccgtac agcattggcg actcatacat cagtgaactg
    16321 gcgacgcgcg agaatttacg cctcaacggg attgatgagt cgagcgtgaa gtttctcgac
    16381 agcaccgccg actacccgca acagccgggt gtggtgctga tcaaagtgcc gaaaacactg
    16441 gcattgctgg aacagcaact gcgtgcgctg cgcaaagtgg tcacgtcgga tacacgtatt
    16501 attgccggtg ccaaagcccg tgacattcac acttccacgc tggagctgtt cgagaaagtg
    16561 ctcggcccga ccaccactac gctggcatgg aaaaaagcgc gcctgattaa ttgcactttc
    16621 aatgaaccgc cgctggccga tgcgccgcag accgttagct ggaagctgga aggtactgac
    16681 tggactatcc acaaccatgc gaatgtcttc tcccgcaccg ggctggatat tggcgcacgc
    16741 ttctttatgc aacatctgcc agagaatctc gaaggtgaga ttgtcgatct cggctgtggt
    16801 aacggcgtta ttggcctgac gctgcttgat aaaaacccgc aggcgaaagt ggtgtttgtc
    16861 gatgaatcgc cgatggcggt cgcttccagc cgaatgaatg ttgaaaccaa catgccagag
    16921 gcgttggatc gctgcgagtt tatgatcaac aacgcgctct ccggagtgga gcctttccgc
    16981 tttaatgctg tgctctgcaa cccgccgttt catcagcaac atgcgctgac cgataacgtc
    17041 gcctgggaga tgttccacca cgcccgccgc tgcctgaaaa tcaacggcga actgtatatc
    17101 gttgccaacc gtcacctgga ttacttccat aaactgaaga agattttcgg caactgcacc
    17161 accatcgcca cgaataataa atttgtggtg ctgaaaacag tgaagctggg gcgtcgtcgg
    17221 taagattggg agttacctgc cggatgcggc gttaacgcct tatccggcct acgttcagca
    17281 cgttactccc aggccggata agacgcggca agcgtcgcat ccggcaatgt ctgcccagtt
    17341 ctggaatcgc gcttccataa aacaaaaaat ccctgtcacc atcctctaca ttctcttgtt
    17401 tagcgttgtt caacgtttat gctacatacg tgaagttatg acgcataaag aatacgattt
    17461 ctttaccgct gttcatcgta ctaaggggaa aaaatgattg cgattgccga catcttgcaa
    17521 gcaggagaaa agctaactgc tgtggcacct tttctggcgg gtattcagaa cgaggaacaa
    17581 tacacccagg cgctggaact ggtagatcat ctgctgctca acgatcctga aaaccccttg
    17641 ctggatctgg tgtgtgcaaa aataaccgcg tgggaagaat cagcgcccga atttgcggaa
    17701 tttaatgcca tggctcaagc catgcctggc ggtatagccg tgattcgtac ccttatggat
    17761 caatatggtt taaccctttc cgatctgccg gaaattggca gtaaatctat ggtgtcacgc
    17821 gttttgagcg ggaagaggaa attaacgctg gaacacgcta aaaaattggc aacgcgattc
    17881 ggcatttctc ccgccttgtt tattgattaa cgcgacgtgc cggatgcgtt gcatccggcg
    17941 cttcaaataa cgatttaaat ctccagcgcc agccgtgttc cctgggcaat tgcccgtcgt
    18001 gcgtccagct ccatagccac atcgcagccg ccaattaaat gcacagtttt cccgctatca
    18061 atcagcggtt gcgccagcgc gcggtttggc tcttgccctg cgcagatcac cacattgtcc
    18121 actgctaata cctgcgtttc gccgttgatc accacatgca gcccgtcatc gtcaatcttc
    18181 tgataactta cgcctgggat cattttcaca ccccgcgaga gcagggtggt gcgatggatc
    18241 cagccggtgg ttttgcctaa cccctgtccc ggtttgctgg ctttgcgctg gagcatcaca
    18301 atttgccgtg ggctacgcgg gatctgcatt ccctgcgggc ttaagccacc agcctgttgt
    18361 aggctgctgt cgatccccca ctcattacag aacctggcga tattctggct ggtggattcg
    18421 cccggctgac ttaaatacat cgccgtatca aaaccaatcc cgccacaacc gatgatggca
    18481 accttgttgc ctaccggcgc tttgtcgcgc agtacatcga gataactcaa taccttcgga
    18541 tgatcgatcc cgtcgatagg cggaacgcgc ggcacgatcc cactggcgag gatcgtttca
    18601 tcgaacgcct gtaactgatc cgccgtcacg gtgtgattga gtttcagcgt cacgcccgtc
    18661 acttcgatca tccggtggta atagcgcagc gtttcgtaaa actcctcttt gccggggatc
    18721 tgtttggcga tattaaactg cccgccgatc tcgctgtggg catcaaacaa tgttacctga
    18781 tgcccacgcg ccgccgcgtt aatggcaaac gccagcccag caggtcccgc accgaccacc
    18841 gccagatttt ttttctgcac ggcaggaagg attggcattt tggtttcgtg gcaggcgcga
    18901 ggattcacca ggcacgaggt gactttgcca acgaagatct gatcgaggca ggcctgattg
    18961 cagccaatgc aggtgttgat ctcatcggct cgccccgatt gcgcttttga cagcagttcc
    19021 gcatcagcaa gaaacggtcg tgccatcgat accatatcgg catcgccgcg cgagagaatg
    19081 tcgtcggcaa cctgcggatc gttaatccgg ttggtggtca ccagcggcag cgagacgtgg
    19141 cctttcagtt tgcgcgtgac ccaagtaaat gcgccgcgcg gcacgggcgt ggcaatggtc
    19201 ggaatacgtg cttcatgcca gccaatgccg gtgttgataa tggtcgcgcc cgccgcttca
    19261 atggcctgcg ccagttctac cgtttcggca aaagtgccgc cgccttcgac caggtcgagc
    19321 atcgacaacc ggtagataat aatgaagtcg ttgccgacgc gttcgcgcac cgtacgcact
    19381 acttctacgg caaatcgcat ccggttgcgg taatcgccgc cccactggtc actacgctga
    19441 ttggtgcgca gcgtcagaaa ttcgttgatc aaataccctt cggaccccat tacctctaca
    19501 ccgtcgtatc ctgcctcccg tgccagttgc gcgcagtggg cgaaatcgtc gatcagttgc
    19561 aggatctctt catgcgtgag ttcgtgagga acgaaacggt tgatgggggc ctgcaatgcg
    19621 gagggagcga ccagatgcgg ttggtagctg tagcgcccgg tatgcaaaat ttgcagggct
    19681 attttgccgc cttcctgatg taccgcttcg gtaatggtgc gatggtgtgg gatctggctg
    19741 gcgtcgttga gcattgcgcc accttccatg ccaacgcctg ttaaatctgg tgcaatgccg
    19801 ccgctgacaa tcagcgccac gccgtgacgg gcgcgttcgg cataaaacgc tgccagccgc
    19861 tcggcaccgt ccgggtattc ctccagcccg gtgtgcattg agcccatcaa cacgcggttt
    19921 tttaacgtgg taaaacctaa atccagcggg gcgaacagcg acgggtagct cataaaattg
    19981 tccagtatgt aaaataattg ttatgtggtc ggatgagttc taatttagcc gtcgccggag
    20041 aaaagggaaa aggggagtgc ggggtttgtg atgggattca aaaagaatac gcccggtggt
    20101 aacgccggat gcgacgcttg ccgcgtttta tccggcctgg gggattgcac atgtagggcg
    20161 gataaggcgt tcacgccgca tccgccagtg gcgcggtgca gttgccggat gcaacgcttg
    20221 ccgcgtttta tccggccagg aggattgcac atgtagggcg gataaggcgt ttacgccgca
    20281 tccgccagca gttgcaaatt attgcttacg gaaaaaatcg ttatacaaca tatacaaatg
    20341 cgcggcactc caggagaaat ttggtgcgcc ttgctgtgcg cctgtcagcg ggttgtaatt
    20401 ttcctgaatt ggtccatcgg cggttaaccc tttggcgtgc cggaagaacg tatccgccag
    20461 cttcagggca tcatcacgat aaccgtaacg ctccatccct ttcagaccaa accagaactg
    20521 atccacccat acgcgcccac gccagtagat atcagcgcca aaagccggat tggttaacgc
    20581 cgccgttccc agcgggacaa aggtgttgaa ctctttagga tcgagcatca ccttcaccac
    20641 cgcgtcggca ttggcctgcg ttgccgcacc gttaaacagc ggcgaccagc cttccggccc
    20701 tttaccgcgc tcaacaatcg gtttgcccgc gcagccgttc gccagtggtt tatcttcaat
    20761 acgtacgtca tagtagaact gggtagtcgg gtcgaacata caggtgttga tgtagtccgc
    20821 gagctgctgt gccaactggc gatagcgttt ggcctcttct ggcttaccga ggatggttgc
    20881 catctccgcc agataatggt tatcgctgta catatagctg gcctgatcca ccgactcctg
    20941 caatagcgag tagcccagca acgttccgtc ctgactgcgg ttttcggcga atttcaccgt
    21001 ccagtcgcta cgtttgccgc cgcttgcaac atatttatcc agctgttctt tgtcgataaa
    21061 accaaagacg gcggcatcat cacgccccga ttcccacgac gcagcgacct gtgccggaat
    21121 ttccagactg tcgtactggc ctttctccac cacgcgggcg tagttgttca gcccagactg
    21181 cgtctcttct ttgttgcctt tcttcaccgt aaacagcatc tcgccgctct cagtgttgtg
    21241 ggctttgtcg cgggtcgcgc catattccgg cacgccgttg ccgttgtgat cgcggttacg
    21301 taaccaccag tcgtgatagg ccaccagttt cgggtacatc tctgccaacc aggctttatc
    21361 ctgggtgacg ttgtacactt ccatcaccga ccaggcggca aggctgggtt tggtattacg
    21421 ttcgttccag ttgccgccat cgccaccacg ctcggggcta aggttccacg ctatcaggtc
    21481 ggggacaaag cccacatcct gcggacgcac gctatcgcca ggctggatct gccaggagaa
    21541 gaccgcgcgg atattctctt tggcgatgtc cggattgaaa tgcgccatcg caaacgcctg
    21601 cttccaggta tcccacggcc aggtctgatt gccggagaac cagcgcccgg tcaccgacgg
    21661 tgtaacggtg ttaaatttca ccgcaccgcc cggtgagcgc cagttaccgt tgagcgtttc
    21721 gatcgctttc accgcgacgc gcgtctgttc cggcgtcgca tccggattgg ttaacccttt
    21781 cttcaggtat tcttcccagc gttgctgcga ggcggtgaga taaaacgccg gacgcgccag
    21841 aatatcgcgg atctgcattt gctctttgct aacttcctga gcggtcagca gatgggaata
    21901 ggtggtgtag agcgtggtcg aaccgttgat atgcgcctta ctggtaaagc gattaccgtt
    21961 gatttcagtc tgcaccggca gggatttatg cacctgatat tccgattcgc cggaggtcag
    22021 cagatcccag gtggcgcgca ctttgccaaa ggtgactttc aggccatcac gggtggcgct
    22081 gattttgcgc tgatagtcag ggtattcgcc agcaatggtt ttatcggaaa gcggtttccc
    22141 ttctttcgct tccagttttt ccagcagttc gccgtcccac accagatcca gcggtttatt
    22201 gctggtgatt ttggtttcca gtagtgacgt gcgcggcgtg gcgaagcgca gagtcatttc
    22261 gacttgcaca tcttttgctg tcagtttttg caccagcgca ccgggaatac tgtatgcctc
    22321 cagcgtaaag tcgactttct tgccgtcctg ccagacggtc aggcggtcga aattgctggc
    22381 cataaagttg atgtactctt ccgtcagcag cgcaacgccc ggaaagccgc ccatggtgtt
    22441 agggccgtct ggcaacagat gaccatgcca ggctccgaga tcgaaaaacg gattaaaacg
    22501 ctggtgatcg tcgtaatcgt aatccttcat gtactgcggc gcgccagtac ggttaatcac
    22561 gtttttataa ttgtcggcgt tagcggcatg ggcggaaaaa cttatcagca gagcgcaggt
    22621 tactggcgtt aaaatagttt ttattttcat gaaattacag tccttattac cagtagaaat
    22681 attgcatcag gaagatttgg tcgctgggat cgtgagaggc atttttcatg tagaagcggc
    22741 tatcaaaagc cgtggcgaaa cgtccgccgc cgtattcgta ccagatacca aactgcatga
    22801 aagaggtggt ttcatcgtca gcgtggtcag ggcgatgttt ggcgtaggtg taagcggtgg
    22861 agagataaac gccctttaac gcttcataca tggcgctcac catcatccca ctttcacttc
    22921 ccggtacgtc cagcccgtcg gcgcgtccgg tatggtgcca ggcgcgagcg gcaaagttag
    22981 gagttagcag gcccgtgaga tagagctgtc ctgtgccgtc ggtgatttcc agaccgttca
    23041 tccaggtgat gccttcggca aggtcatact ggatgtaacc gttcatcatt gccggatagg
    23101 tgtatttgtc gtcatagcga tcgtacttgc caaaatgtag ccaggctttg ctttcgtcat
    23161 gatgtccggc aggtgtggcg gtgacgctat aacgaaagtt gccgcttaag ttctgcacct
    23221 tcagcgcggt cataatgtcg cgggtattgg gaatgacgta gcccagatcg ggggtgaagt
    23281 cgccccacca ttgcaggtca tccagcgagg aatcctgacg cagactgagc atgatttcgg
    23341 tgccatcatt ggtacgataa ccgccataga aacggttaat tccgccctcg aaaccacccc
    23401 agctatggtc tggcacccag gcattgccgt cgtggtcggc ctgcacggtc cagccttcgc
    23461 cgtaaatcag gccgaaccag gagccgtact tcatctccag gccaccttca atataggtac
    23521 cgtcgctgta tttatgttta ttctcaccct ctaaatccat atatccacca acccctaatt
    23581 cgccgtaaaa acgaaatgaa ggagaagatg tcgaggtaat tgcaggtgtt tttgtgtcgt
    23641 catgttctgc cggacgtgct tcttctcctg ccgcagaaaa ggcgtagcaa aacggcagag
    23701 caagtaatgc tctgcatggt gcagtgatta atttcattgt gttaatccat gagctaaaga
    23761 aaaagtacag ccttttatcg ttgtaattat aaaaatataa aggcagaaac tattttccct
    23821 ctcctcatcc aggaagaggg aaaatgcctg ctcatttttt attattctgc ttaatcaaca
    23881 ttgctggctg gcgtcgcttc aatatggcgc tcttcagccg ttaatccctt tatatattta
    23941 ctgtatttcc accacgcaaa gccaaggaag ataacaatac cgccgacgtt ataaaaaatg
    24001 atggtcagaa tattcgcgcc agtcgggaat gtcgaagcga caaaccctac ggcaaatatc
    24061 gcaatcagca ttgaaacaac gataataccg gtgcggcggg agcccatacg gaaatcgcgt
    24121 ggcaggtgat ctaatttggc gcgtaaattc aggtaagcca gcatgatgaa taacggcgga
    24181 agcatggacg ctgcggcggt catattaata atagtattca tcagatcctg cacggtattg
    24241 gaaccgagca tcgggataat catcagcggg atgacgatca ggaactggat ccacgctgcg
    24301 cgcgccggaa cgccgttttc gttcagttcg acggttttct taccaaagat gccttccggg
    24361 atttcggaga agaaaatttt caccggcgtt gcggtccaca tcagcaggga accgaacatc
    24421 gcggtaaagg acaccagacc gacaaagcga ttcatcaacg cttccggtag accaaaatac
    24481 gccgccatgc cgtggaatac ctgcaccgat ccgccggtaa atttcaactc tttgctgctg
    24541 acgaagacgt taatcagcac cgaggagacg gaatacagta cgccgataaa aatcccggcg
    24601 aggatgatca ctttaacgaa cgatttcgaa ccgcctttga cgtcgttaac gtacacagcg
    24661 acggactccg cgccacctgc ggccataaag atccaggtgg taacgccgag gaacgcccag
    24721 ttgaagttcg ggatcatcgc gtcaacggtg atggggtcag caggctgtac gccgccaacc
    24781 agcgccgtac ctgccagtaa aatgtaggag agcgttaaca gcagcatcag cgttgaagtg
    24841 acggaggtaa ttggccccag cattttcgcc ccgttggtgg aaacccaggt ggagaaggcg
    24901 aacagcacca tactgataat ggtggtggca accggcgtca taatatattc gtagccgagg
    24961 aaggcatacg aagcataagc aataacgcgc ggcaacagtg aggtgaaaaa gaacaggttt
    25021 acgaaccagt aggtataggc agtaataaat gcccaacgtc cgcccagcga actttttacc
    25081 cacgcgtaga caccggcttc tgagttttta tttaacgaaa caaattctgc gatgatcaga
    25141 cagaagggaa taaaataaaa aatcgtcgcg aggaaaaaca tcggtgccga ggccagtcca
    25201 agctcaatat tattattgat aacgttgtta aagctgtaaa cggcggcaaa agtcagcgag
    25261 agcaagccga atttgccgat tgtattacgt ttggtatcag acataacaca tctccgaaaa
    25321 tgtgtagggt agcggtggcg gcaaactcct tttgccgccg tagttgttat ttgttatgga
    25381 aataaccatc ttcgatggtg actttgagaa ccactttttt gaccgcgtta ttgcagataa
    25441 accgatacgc ttcatggata tcgcaaataa cgatttgccc ttcgtggacc tcaacggttt
    25501 ctccgcagcc ttttaaatat tcacggtcag tttcatcacg ataatattcc actacctgta
    25561 atgtctcttt cggcgcatat tcaatttttt gctgcccttg caggtagtaa tgcacttcaa
    25621 aatagcgtcg atgcccggta aatagcgcat cggtcgcgga gtctgtctcc acgcggtaag
    25681 tcaatgagtc accgatggag tgggcgacgc caggctgaat gttgtcgata ttttcaatcg
    25741 cttcaacgca gcgttgccac ttcttgccag aggcgtaaat ctggcggaac tgttctaagt
    25801 tatcgatgat cctcattgct tattctcgct gtgcaaattc gtggaaaaga accctgcgcc
    25861 gaactcatac gacgccaggc tttgcgcggt agcttctccg ccagaaaccg gcagcaacgt
    25921 aaagccgtag ctgaagtcac ggaaccagac gcgccaggag tccagcacct cgctgcccca
    25981 ggagttggag ccgaggccaa gcagctggtg gtcgaggttc agggtgatgt catcactgcg
    26041 ctgcagctcg ttacagtgct gggcagcgtg gatgttttcc tgggtatagc gccaggcgct
    26101 gaagttaatt gggcgctgcg gaaccaccag cagaccgttg ccgtggcggt tagtcagtgc
    26161 cgtccagcgg acatgctgac ggttgccgtt gttctgcggg aagggatagt tctcgaacat
    26221 ggcatcgacg gtgctgcgcc agatatcgat gatgttagcc tgctggctgt cggcgtagtt
    26281 ttcgcccggt ccacgaccgt aatacgccac ctgatcgtat tcgccgttaa tccccatggt
    26341 gaaaccgatg cacggaatga tgtgcggata gtcgccgtaa cgctcgccgg aaagcgccac
    26401 gttaacctgg ccatcggcag cgatgcgcca gatgtaggtg cagcgcatcc cgaagtcaaa
    26461 caccggcggg gcaataactg tgcggctgat gatcaacact tcaccatcgc tctgttctac
    26521 ggcaaagtcg cgcagatgtt cctgcatgat ctgcaaatga ttcggttgcc acagcccttc
    26581 gtactcctgc ttgtggttgt cgatcattgg cttgaagaag ttgatctttg gctcgcgggt
    26641 cagcagcgac tcgccattca cctgccagga tgtcggtttg ccactcattt ttgagaaggt
    26701 gatcgcgaag ttgtagccgc gaacggtgca gctcaaacga tcgtcttcca gcgtcagcgg
    26761 acgcgcatta tttggtgcga aaggcactgg ttgcgcggtg ttttccttca gcgggaactg
    26821 ataagtggcg atagaatgcc cggcttcgct gtagcgggtg cgggaatctt tggtcaccgt
    26881 aatgttgagg aacgcttcgc gggcgtccag ctgcggcagc gtgatctgca agggggcttc
    26941 gctgttcggc gcaacgtcgc gcagtttaat ctgctgcgtc gcgagcgttt caccttcgac
    27001 gcgcacctct gcgtgcaggg tgtagtcatc aagcgtggta aaccacagtt tattttcgac
    27061 tttcagctcg ccgcgagtca gatccagcgc gtggattttt accggcgcga taacctgttt
    27121 gtactctttc aggcccggtc ccggcgtctg atcggaatag atcaaaccat caagacagaa
    27181 gttatagttg ttgggatagt cgccgtagtc gccgccgaat ttataccaga cgttgccgtt
    27241 gtcatcctgc gcctggatcc cgtggtcgca ccactcccaa acataatgtc cctgaataca
    27301 atcgtgctta tagaagacgt tctggtactc cgtcagcccg cctggtccgt tccccatcgc
    27361 atgagcatat tcacagatga tgcgcggctt cggatgcggg tattcaccaa actcattcat
    27421 cagcggcacg cgggtgtaca tggtggaaat aatatcgacc acttcagcat cgcgatcttc
    27481 ttcgtaatgc accagtcgcg tgtcatccag cgccttcgct gcgtggtaca tcgcgcggat
    27541 gttacagcca tagccggatt cattgcccag cgaccagatg atgatcgacg gatggttttt
    27601 ctgcgcgtga atatggcgaa caatgcgctc gacgtagact ttttcccact gcggatcgtc
    27661 ggtaatacgg ctgatatcgc cgacattagc aaagccgtgc gattcgacgt cggtttccgc
    27721 catcacaaac aagccgtaga tatcacacag ttcgtaaaaa cgcggatcgt tcgggtagtg
    27781 agcggtacgc acggagttga tattgtgctg cttcatcaac tggagatctt tctcgacgcg
    27841 atccattcca acggcgcggc ctttgcgatg atcgttgtcg tgacggttga cgccgtgcag
    27901 catcacataa cggttattga tccagaacag accgtcgcgc actttgatat cacggaagcc
    27961 aacgcgttgt ggcaccactt ccagaacgtt gccgttggcg tctttcagcg tcatgaccag
    28021 atggtaaaga taaggggatt ctgctgacca ttgctgcggc tgttcgacag taaaagcaaa
    28081 gctggcgctg gtcagttttt caattgccaa atgatcaatg gcgctgctgt gcaccacgcg
    28141 ttcgccatca aacagggtat attccagcgt cgtgacgaca ggggaggcgg cgagattttc
    28201 cagcaccact tcgcaggaaa gtgtggcatc gcaataggct tcgtcaaagt cggtacgcac
    28261 agtgaaatcg ttaatatgcg ttaggtgttt tccgaccaga taaacatcgc ggaagatccc
    28321 cgctgaccac cacatatcct ggtcttccac gtaggtagag tccgcccact gcatcacgcg
    28381 cacacacaac aggttgtcgc cggttttaac catcgcgctg atgtcaaact ctgcggtcag
    28441 gcgactgccc ttgctgaaac ccacatactg accgttaaca tagacttcaa aataggtttc
    28501 gacgccgtca aatttaatca gcgtctgttt accctgccag ccgtcgctga gggtgaaaat
    28561 acgttgatag gcaccggttg ggttatcgct ggggacaaac ggcacatcga tggggaacgg
    28621 aaaaccttcg tcggtatatt gcagtttgcc gtgaccttcc atttgccaca tggcggggac
    28681 ggtaatatgc ccccagtcag ccattaactc agaggtgaag gcttctggta cttgcagcgg
    28741 atggtcaaaa aagtggaaat tccactgacc gcttaagggc agaaacaggc tgctggtttc
    28801 gcgggcaaag gtacgcgctt gcgcaacaga atcatatgaa aaaaagtacg cacgcggcgc
    28861 aagtcggttt tcgtgggtga gctgaatgtt ttcccagcga ttcatagggc ctcccggtag
    28921 agagaaatcg gaaccattca tggtgatggt agtttgtgta attgctgggg agtttagtaa
    28981 aatttttact aaaaagtagc aggtaaatgc atttacttta actggatcac gaaaataaac
    29041 ggcagcactg tccggcaaaa acgattgccg gacagtgtgt aaggggattt aacgggtcgt
    29101 gccgcgcagt tttaatttgc tgggaacgaa gactaacagc ggcagcgcgc gaccatcgcg
    29161 ggctttttca tacaccaggt taacgccctg acttcccatc atctcggaat ggatgcgcac
    29221 ggtggagagc ggcggaaagg taaatcgcgc ggtggggata tcgttaacgc tgataagcga
    29281 aatatcctgt gggatgttca ggcctcgttc atgaattgcc cgcagtacgc cgatagcaat
    29341 ggaatcggaa gcaacaaaca gtgccttcgg atagtcttcc cgcgccagca tttgttttgc
    29401 cagttcataa cccgacgaac tggaaaaacc gccgcgccag atatcctctt cgcgtaccac
    29461 ttgtttcagt cggctatatt ccgcaaaggc gacctcacga atatccgcct tgccaggctc
    29521 atcttcaccg caaataaaac caatacgatt aacgccctgg ttgatataga agtcgatgat
    29581 ttctttactg atgcgtgcca gatcgatatc caccgcatcg taaccgctgc cgggttcgtg
    29641 aaagtcgata aaacagatat tgtcggtcaa cgcacaggcg gcggcgcgca gggcgggcgt
    29701 gggtttgccg acaattaaaa taccggtgac gtttttaatg tctggtaatc cgctgtgttc
    29761 ataacagttg gtgagctcaa tgcccagctt ttcgcactga gtttcaatgc cgtggcggat
    29821 cgccagatag taaggatcgt tgatctccag ctcctgttgg tagctgtaga tagccagaat
    29881 atggtgttgg ttgactgcac ctgtctggag tttacgggca ctactggtct tgtactccag
    29941 cttttcggcg atctcgagaa tgcgatgttt cgtctcttct ttcacattca atgtcggatc
    30001 gtcatttaag accctggata ctgtcgccag ggatacgcca gcttcgattg cgatgtcttt
    30061 tagtgttgcc atgtttacct tttttacttt ccctgatgtg cgcccccatt gtagaggaag
    30121 tgcttatcgg gtcacctgtt ttcagtaaat aaagcgcgtt tctttgacgc tgtaacggta
    30181 acacagcggc tcacgaatgt gatcacgcct gcattctcca tttttagcct acaggattga
    30241 gaaaaacttt tgctatagtt tagtaaaatt ttacccgaag ggaggaaaca atggaaaccg
    30301 tggcttacgc tgattttgca cgtctggaaa tgcgcgtcgg aaagattgtg gaagtgaaac
    30361 gccatgaaaa cgccgacaag ctgtacatcg tacaggttga tgtgggggaa aaaacactgc
    30421 aaaccgtgac cagcctggtg ccgtactaca gcgaagaaga gctgatgggg aaaacggtgg
    30481 tggtcttatg caatctgcaa aaagcgaaaa tgcgtggtga aacgtcggaa tgcatgctgt
    30541 tgtgtgcgga aaccgatgac ggcagtgaaa gcgtgttgtt aacgccggag cggatgatgc
    30601 ctgcgggcgt acgcgtcgta taaaaagatc ggatggcgac gtcgtatcgc catccgattt
    30661 gatattacgc ttcttcgaca cttactcgca tggccgccag cgccttacgc gccgctttga
    30721 tcaccagttc acactgttca atggtcagtg tcagtggcgg ttcaatgcgg atcgttttgg
    30781 cgttattgag cgttccggcc accagtacgc gctggcggaa catctcgctg gcaaagttat
    30841 agccgatttc gttatcaaca aactcaattg ccatcaacat ccctttacca cgcgcttcct
    30901 gtaccagatc gggatattcc cgcgccagtt gacggaaacc gtccagcaac atatcgcctt
    30961 tttgctcagc ctgagccggt aagttctgct ccagcaacac attgatggtc gccagcgccg
    31021 ccgcacaggc cagcgggttg ccgccaaagg tggtggtatg caggaatggg ttgtcgaaca
    31081 gaactgaaaa cacctcttca gtggcgatgg tcgcgccaat cggcatcacg ccgccgccga
    31141 gcgctttggc aaggcagagg atatccggct gtacgttctc atgctcgcag gcgaacatct
    31201 tgcccgtgcg ccccatgccc gtttgtactt catcgaggat catcagtgcg ccgaactcat
    31261 cgcatagctt acgtacggcg gtgagatagc ccggcggcgg cagaattacg ccaccttcac
    31321 cctgaatcgg ttcgaggatc accgcagcca catcatcacc ggtttttttg cactcgttaa
    31381 gagccgtgcg catggcttcg atattgccaa acggcacatg acggaagccc ggcagcagtg
    31441 gcataaacgg tttgcggaag gtcgatttcg ccgtggccga cagcgcgcca agtgatttac
    31501 cgtggaacgc gccgctggtg gcaataaaag taaacttgcc gcgcggtgac tggtaagctt
    31561 tcgccagctt cagcgctgct tcaacggact cggtgccgct attacagaag aagctgtatt
    31621 tcagtttacc gggcgttagc gcagcaaggg ttttcgccaa catcgcccgt aacggatcga
    31681 gcagctcctg gctgtgcagc ggttgtttcg caagttgatt ctgtacggcg gaaaccacaa
    31741 ctggattacg gtgccccacg ttgaaaattc caaaacctcc caggcagtcg ataaactcct
    31801 gtccctgggt gtcgacaagc gtatttaaac ctcccgcttg ccactctacg gctccgtaat
    31861 ccccgccggc ggtaacagat ttgcgatact ctaaaaaccc cggattgaca tgctctttga
    31921 agtattcaat cacctctcgg ttaagtgctt tcatctcctc atgatccagc gttcgcttct
    31981 caatgagatt cagggcgtgg gcgctgcacg ctaaagccga tgcgctcgaa ggtaacctgt
    32041 tcaaaatatg ctccggaggc tcgcgtatca catgataccg atttaagtat tgcagggatt
    32101 gcgccactcc ggctgcgatc gcgaaaatcg ggataaacac aaattcggtt atcatttgtg
    32161 caatatttaa tgctatctgt taacatttgt tgttattttg cacggttttt gtcgggtatg
    32221 gatttgatga ttgctgcgca aatgcacgtt ttcagggcaa taattgcctg atttttgggc
    32281 aagataatta acgttttcgt atagtaacag agtgaaagta ttttaaatca aagaattaga
    32341 tttgtgcttt aatcgcaaat tgcgatctaa atcaaattaa tcggttaaag ataaccgcag
    32401 cggggccgac ataaactctg acaagaagtt aacaaccata taacctgcac aggacgcgaa
    32461 catgtcttct catccgtatg tcacccagca aaataccccg ctggcggacg ataccactct
    32521 gatgtccact accgatctgc aaagctatat cactcatgct aatgacactt ttgtgcaggt
    32581 gagcggcttt accttgcaag agttacaagg gcagccgcac aacatggtgc gtcacccgga
    32641 tatgccaaaa gcggcgtttg cggatatgtg gttcaccctg aaaaaagggg agccctggag
    32701 cggcatcgtg aaaaatcgcc gcaaaaatgg cgaccattat tgggtgcggg ccaatgcggt
    32761 accgatggtg cgcgagggaa aaatcagtgg ctatatgtcg attcgtaccc gggcgacgga
    32821 tgaagagatt gcggcggtgg agccgctgta caaagcgctg aacgccggac gtaccagtaa
    32881 gcgtattcat aaaggcctgg tggtgcgtaa aggctggctg ggtaaactgc cttcattacc
    32941 gcttcgctgg cgggcgcgtg gagtgatgac cctgatgttt atcttgctgg cggccatgct
    33001 ttggtttgtt gctgccccgg tggtgacgta tttcctctgt gtgttagtgg tattgttggc
    33061 aagcgcttgt tttgaatggc agattgtgcg cccgatagaa aatgtcgccc gtcaggcact
    33121 gaaggtggcg accggagagc gtaatagtgt tgagcacctg aatcgcagcg atgagctggg
    33181 gctgacatta cgcgcggtag ggcagcttgg cctgatgtgc cgttggctaa ttaacgatgt
    33241 ctcaagccag gtgtccagtg tcagaaatgg cagtgagacg ctggcgaaag gcaccgatga
    33301 actgaacgaa catacccagc agacagttga taacgttcag caaacggtgg cgaccatgaa
    33361 ccaaatggcg gcgtcggtga aacagaactc tgccacggcg tcggctgccg ataaactttc
    33421 tatcaccgcc agtaatgcgg cagtgcaggg tggggaggcg atgaccacgg tgatcaagac
    33481 aatggacgat atcgccgaca gtacccagcg cattggcacc attacttcgc tgattaacga
    33541 tattgcgttt cagaccaata ttctggccct gaatgcggcg gtggaagcgg cgcgtgccgg
    33601 cgaacagggc aaaggttttg cagtggtggc aggggaagtg cgtcatttag ccagccgcag
    33661 cgctaatgct gccaacgata ttcgcaagct gattgatgcc agtgctgata aggtgcaatc
    33721 cggttcgcag caggtacacg ccgccggacg gacgatggaa gatattgtgg cacaggtgaa
    33781 aaacgtcacc cagttgatcg cccagattag ccattcaacg ctggaacagg ccgatgggct
    33841 ttccagcctg acccgtgcag tggatgagct taacctgatc acccagaaaa atgccgagct
    33901 ggtggaagag agtgcgcagg tgtcggcgat ggtgaaacac cgcgccagcc gactggaaga
    33961 cgcggtgacg gtgctgcatt aatcggtatg ccggatccgg cggttggagc acaatgcctg
    34021 atgcgatgct ggcgcatctt atcaggcctg cggggtgtgt agcgggtgta ggccggataa
    34081 ggcgcgtcaa gcgtcgcatc cggcaattgc accgcgccac tggcggatgc ggcgattaat
    34141 ccagttgcgt aatatcaaaa gcggcgcggt cgatcaccgc aatgatcttt tttatttgtg
    34201 catcactgat atcgctctgg ttgacgcgta aatccagcac cgctttaaaa ttatccagcg
    34261 cccgcttcat ttgcgggttc tggcgcagcg ccgcgccaac gcaacgcgct ttgatgcgtt
    34321 cttcaatcat ctccacctgt tcgcggtttt cttccagcca ctgcgcgcct tgttcggtca
    34381 gcgcaatctg cttcttacca ccttcctctt cgcggatggt aatcagcgac tgctcctgca
    34441 gaaaatccag cgttgggtag atgacgcccg ggcttggggt gtaattcccc tgggttaggt
    34501 tctcaatcgc tttaatcaat tcgtaaccgt ggctgtcatc gcgcgagaga atatccagaa
    34561 tcaccagacg caattcaccg tgaccaaaga aacgttgccg acgaccgccg ccgcgaccgt
    34621 ggcgaccacc gcagcattga ccgtgttcat gctggtgacc gtgtccgcag tgctcgtgtt
    34681 ctgacttctc acctttgcag cagccctcat ggcgtggctg gccttcatgt ttacaacacc
    34741 cttcgtgatg atggctcata tcagcctcct tttgcttgat tagatatatc taatttatat
    34801 ctgatgtgag cactcttgca agaataaaaa tgatttttaa atgtggactc atctcacacg
    34861 taggccggat aaggcgttca cgccgcatcc ggcgttgagt aatgatgcct gagaagaggc
    34921 ggttcgtctt gtcagactat agacatatca gttctacaaa tcgcttgcat ttatcatgat
    34981 taacaatcat tatcatttgc gaaaattatt tagatatatc tgattaccat cacgaaggcg
    35041 ataacaatga ataactcccc ccgctacccg cagcgcgttc gcaatgatct gcgcttccgt
    35101 gaattgactg tgctacgcgt tgagcgtatt agcgccggtt ttcagcgcat tgtccttggc
    35161 ggcgaggcgc tggacggttt tacatcgcgc ggctttgacg atcacagcaa actcttcttt
    35221 cctcaatctg atgctcactt tgtgccgcca acggtaacgg aagagggcat cgtctggccg
    35281 gaaggaccac gcccaccgtc gcgtgactat acgccgctgt atgacgaact acgccatgaa
    35341 ctggcgattg atttctttat tcacgacggt ggggtcgcca gcggctgggc gatgcaggcg
    35401 caaccgggcg ataaacttac ggtggcaggt ccgcgcggtt cgctggtggt gccggaagat
    35461 tacgcgtatc agctgtatgt ctgcgatgaa tccggaatgc ccgcactgcg ccgccgcctg
    35521 gaaacgttga gcaaacttgc cgttaaaccg caagttagtg cgctggttag cgtgcgggat
    35581 aacgcctgtc aggattatct cgcgcacctt gatggtttta atatcgaatg gctggcacat
    35641 gatgagcagg cggtagatgc gcgtctggcg cagatgcaaa tccctgccga tgattacttc
    35701 atctggataa ccggcgaagg taaagtcgtt aagaatttaa gccgccgctt tgaagcggaa
    35761 cagtatgacc cacagcgggt acgtgcagcg gcttactggc acgcaaagta actgatatat
    35821 aaaaagaaaa aggctgacga tttctcgtca gcctttgcta tatctggtgg cccctgctgg
    35881 acttgaacca gcgaccaagc gattatgagt cgcctgctct aaccactgag ctaaggggcc
    35941 atggtagcgg attataaagt aactccgtgt cgcaatccag ccattaccgt gcgcctgctg
    36001 tttttataaa caatgtattt tcaatccgtt atacttttcc tggtgatgtt agaaaggagt
    36061 aaatatggtt gaggatattt tggctccagg gttacgggtc gtgttttgcg gtatcaaccc
    36121 tgggctttca tccgccggga ctggttttcc ctttgctcat ccagcaaatc gcttctggaa
    36181 ggtgatatat caggccgggt ttaccgaccg tcagttgaag ccgcaggagg cacagcatct
    36241 gctggattat cgttgtggcg tcaccaaact ggtagaccgt ccaacggtgc aagccaatga
    36301 agtttcaaag caggagctgc acgcaggtgg gcgtaagctg attgaaaaaa ttgaagatta
    36361 tcagccgcag gcgttggcga ttctgggcaa acaagcatat gaacagggat tcagccagcg
    36421 cggtgcacag tgggggaaac aaacgctcac cattggttcg acgcagattt gggtgctgcc
    36481 aaatcccagc ggtttaagtc gcgtttcact agagaaactg gttgaagcgt atcgcgagct
    36541 ggaccaggcg ctggtagtgc gtgggcgata aaaaacgcca ccgaaaaggt ggcgtttgtg
    36601 caaagggact agtgccgggt gcggcgtaac gcctgatccg gcctaccgat taatcgtcca
    36661 ggaagctacg caacacttca gaacggctcg ggtgacgcag tttgcgcagc gccttcgctt
    36721 cgatctgacg gatacgttcg cgggtaacgt cgaactgttt acccacttct tccagcgtgt
    36781 ggtcggtgtt catatcgata ccgaaacgca tacgcagaac tttcgcttca cgcgcggtca
    36841 ggccagccag cacgtcgtgc gttgccgcac gcaggctttc ggtggtcgca gaatccagcg
    36901 gcagctcgag ggtggtatcc tcgatgaaat cccccagatg cgaatcttca tcatcaccga
    36961 tcggcgtttc catggagatt ggctctttgg cgatcttcag cactttgcgg atcttgtctt
    37021 ccggcatcag catacgttca gccagttctt ccggcgtcgg ttcacggccc atctcttgca
    37081 gcatctggcg agaaatacgg ttgagtttgt tgatagtctc aatcatatgc accggaatac
    37141 ggatggtgcg cgcctgatcc gcgatagaac gggtgatcgc ctgacggatc caccaggttg
    37201 cgtaggtgga gaacttgtaa ccacggcggt attcgaattt atcaaccgct ttcatcagac
    37261 cgatgttgcc ttcctgaatc aggtcaagga actgcaagcc acggttggtg tatttcttgg
    37321 cgatagaaat aaccagacgt aagttcgctt caaccatctc tttcttcgca cggcgggctt
    37381 tcgcttcacc gatggacata cgacggttga tatctttaac ctgctcgatg gtcaggccgg
    37441 tttcttcttc aatctgctgc agtttctgca gggcgcgatg cacttcttca gagacatcgt
    37501 gcagtttttc cgaccacggc ttgttcatcg caattgccgc gttgaaccag gtatcgctgg
    37561 tttcgttgcc ggtaaacagg gtaatgaagt ttttcttcgg cattttgcac tgctcaacgc
    37621 agagcttcat gatcagacgt tcttgcgtac gaacgcggtc catcatgacg cgcatgctgt
    37681 tgaccaggta gtcaaactgc ttcggcacca ggcggaactg tttgaatact tcagacagtt
    37741 tcaggatctc ttcctgagcg gcagcgtgac tgcgaccttt cgctttgatg gtgtcacgcg
    37801 ttacaacgta ctgagcgcgt agttccgcaa atttttcgcg agccagttcc gggtcgatgc
    37861 tgttgtcatc atcggcgctg tcgtcatcgc catcttcttc gtcttcatct tcgtcatcgt
    37921 ccagatcttc ctgggaaagc tcagaaccga cgtgagtggc ggtaggtgcc agatcttctt
    37981 ctgcgttcgg gtcaacaaag ccggtgatca gatcggacag acgcgcttct tctgcttcaa
    38041 cacgatcgta ctgttccagc agataggtga tcgcttccgg atattcagca acggagcatt
    38101 gaacctggtt gatcccgtct tcaatacgct tagcgatgtc aatttcgcct tcgcgggtca
    38161 acagttcaac ggtgcccatt tcacgcatgt acatgcgtac cgggtcagtc gtgcgcccga
    38221 tttcagattc cacgctggaa agcacctgcg cggcggcttc ggcagcatct tcgtccgcgg
    38281 tgttttcagc cagcatcaga tcatcggcat ccggtgcttc ttccatcacc tgaatgccca
    38341 tgtcgttgat catttggatg atgtcttcga tctgatctga atcgacgata tcttccggca
    38401 gatggtcatt gacctcggca taggtcagat agccttgctc cttaccacgg gtgacaagaa
    38461 gtttcagctg tgactgcggg ttttgctcca taagacggta tccacactta tttcatgagg
    38521 ttggtgttgg gcgattgacc cgatgtcctt cagccgttaa cgctgaaatc caacggttgt
    38581 ttaccgccaa cgataattac gagggcgtac ttatatattt gccgctgcct ctcagtgcgg
    38641 ctgtcggggg cttcccgatc gctcttcggc acttaagccg ttaaatcact ttttcgccag
    38701 ctcctggttt aatgtccaga gctccaggcg ttcttcgttg cttaaaccat gcgtgcgctc
    38761 acgagcgatt aactcttcct ggcgcagttc aagcagcgaa tcaaacatat ggttgagtga
    38821 gtcggtgaag gtttgctcag caatattctt atctgctata tcgtcccaca tcgacagttt
    38881 ttcaagggtg gcagcattat ttgtaccacg atagtgctct aaaagttgcc cggtggtcag
    38941 acctggctgg gagagacaag tgttgaccag ttctctgaat aagccaagtc cagggagctt
    39001 attttcatcc agattctcaa gcggcgggac caacgtcgct aattctggat tttgcaccag
    39061 caaccctata agtatacgca tggtcgtgcg ttttagctgc ggaacagggc gagaaacgcc
    39121 gctctctgcc gcttttggca ttaatcgttc aagctggctg tcatcaagta tgcctaattt
    39181 gttgcctaat tcctgacgaa gatatattcg cagcgtttcg cccggcactt gcgatatcaa
    39241 tggcagtgcc agcgtactca aacgtgcgcg cccgtcaggg gtactcagat caacttgcgg
    39301 catcaggctg ttaaacagaa atgcggaaag cggcatcgcc tgctccatcc gcgcttcaaa
    39361 cgcttcttta ccctcttttc gtaccagcgt gtcagggtct tcgccatccg gcaaaaacat
    39421 aaagcgtagc tgacggccgt ctgtcatgta aggcagcgcc gtttccagcg ctcgccatgc
    39481 ggcatcgcgg cctgcacggt cgccgtcata acagcaaatg acattgttgg tcgcgcggaa
    39541 caacagttgt atgtgatcgg cggtggttga cgtacctaac gacgcaacgg cgtaattaat
    39601 gccgtattgc gccagcgcca ccacgtccat atagccttcg accacaagca gacgattggg
    39661 ttcagcgtta tcctgctgcg cttcataaag accgtaaagc tggcggcctt tatggaaaat
    39721 gtctgtttcc ggcgagttca ggtatttggg ggtatcgttg cccagcacgc gcccgccaaa
    39781 accaatcacc cgaccgcgtt tatcgcgaat ggggaacatc acccgctcgc ggaaacgatc
    39841 gtaactgcgt ccctgatcgt tagtgaccaa catccccgca tcaatcaatg actggcgatt
    39901 ttctggattg ccgccaaacc gcttcaggac gttgtcccag ccggggggcg caaaaccaat
    39961 cgcaaagcga gcgataacct cgtggcttaa tccgcgtttt tccagatact ggcgcgcaga
    40021 cgtggcaaca ggttgttgta aagattgttg gtaaaacgta ttcagaccgt ccatcaactg
    40081 ataaagcgtt tgcctctgat ggcgctcgat ctggctgggg ccgctgcctg cttcaaatgg
    40141 cacttcaaga ttgtgcattg ctgccagctc ttcgaccgtt tcaacgaact cgagcttgtc
    40201 gtagttcatc aggaagtcga tcgcgttgcc gtgcgcgcca catccaaagc agtggtaaaa
    40261 ctgtttctca ccgttaacgg tgaatgacgg ggttttctcg ttgtggaatg gacaacacgc
    40321 gtggaaattc ttgccctgct ttttcagctt cacacgggca tcgatcagat cgacgatgtc
    40381 agtgcgtgcc agcagatcat taatgaatac gcgtgggatt cgtccagcca taggccccga
    40441 tttttagcaa ttcataaacg aaaataagcc gcgcattcct ttcggaagca cggccttaca
    40501 actacaactc ggtctgatcg gagagcaacg ctctcgggga attagtacag acgagtgcgg
    40561 cgtgcgtttt cgcgagccag tttcttcgcg tgacgtttca ctgcagaagc tttagcgcgc
    40621 ttacgttcgg tagtcggttt ttcatagaac tcacgacgac gaacttccgc cagaacacct
    40681 gctttttcgc aggaacgctt gaagcgacgc agagctacgt cgaacggctc gttttcacgt
    40741 actttaatta ccggcatgtg cctctcacct ttgattaatt cggtttgccg ctggcatcaa
    40801 cgccagctta tttcaaaatg gtgcggaatt ttactgcaat tgctgctgct ttgtaaagca
    40861 ccgcggcctt tttgaaaggg acttttataa gggtgaggag tatacacgag gctttctcca
    40921 ggggcgaaca aagttttaca tcaacccgca ttggtcctac actgcgcggt aataaagcga
    40981 ggtaaaacaa gtcatgcgtg tactgggtat tgaaacttcc tgcgatgaaa ccggcatcgc
    41041 catttacgac gatgaaaaag gtttgttagc caaccaattg tatagtcagg tgaaattgca
    41101 cgctgactac ggcggcgtcg tgcctgaact ggcctcccgc gatcacgtgc gcaaaaccgt
    41161 accgttgatc caggcggcgc taaaggagtc tggcttaacg gcaaaagaca ttgatgctgt
    41221 ggcctatacc gcaggccctg gattagtcgg cgcactgctg gttggcgcaa ccgtggggcg
    41281 ttctctggcg tttgcctgga acgttccggc aatcccggta caccatatgg aagggcatct
    41341 gttagcgccg atgctggaag ataacccgcc ggaatttccg tttgtcgcgc tgctggtgtc
    41401 cggcggtcat acgcagttaa tcagcgtgac tggcattggt cagtacgagc tgctcggcga
    41461 gtctatcgat gatgccgccg gtgaagcgtt tgataaaacc gcgaagctgc tggggctgga
    41521 ttatcctggc ggaccgttac tgtcgaaaat ggcggctcag ggtactgccg ggcgctttgt
    41581 tttcccgcgt ccgatgaccg accgtccggg gctggatttc agcttttctg gtctgaaaac
    41641 ctttgcggcg aacacgattc gtgacgacgg caccgacgac cagacgcgtg ctgatatcgc
    41701 ccgcgccttt gaagatgcgg tggtcgatac gttgatgatt aagtgtaagc gagcgttgga
    41761 tcagacgggc tttaagcgac tggtcatggc gggcggcgtg agtgctaacc gcacgttacg
    41821 ggcgaagctg gcggaaatga tgaaaaaacg ccgcggcgaa gtgttctacg cgcgtccgga
    41881 attttgtact gataacggcg cgatgatcgc ctatgccgga atggtgcggt ttaaagcagg
    41941 cgcgacggcg gatctcggcg ttagcgtgcg tccgcgctgg ccactggcag agttaccggc
    42001 tgcgtaaaac tatccggtgc cggagagcaa tttccggcac cgtcctcact taaagcaaca
    42061 ccacgggcat ccacagcaag ccggtaatca ccagcaacac gaggaatatc agtccaaaaa
    42121 tcgcccccag tcgccagtaa tccaccgttg gcagataacc actaccgtag taaatcggac
    42181 tgggtccggt ggcgtatggt gtaagaatgc tccccagacc aattgccgcg ccaaccatca
    42241 ggcagaacac cggcagcggg atttccggca tcgccagcgc agcggcaatc atcatcggtg
    42301 cgagggcgga ggtatacgcc gtggcgctgg cgaaaaagta gcgcagcaga taaaacacca
    42361 caatcaacgc caccatcacc atcgttggcg aataaccgct taagctgcct gctaacagtt
    42421 tgccaaacca gctaataaaa ccggtgttgt tgagtccggt agcgagggtg ataagcgagg
    42481 ccagccagaa gaaaacgttc cacgccgctt tattactgac aatgtcgtcc caactgataa
    42541 tgcgcagaag cagcatcagt gccaccacgc tgtaaccgac catcgcggca tcgatataat
    42601 caccgccgaa aatccacagc accagcgcgc ctaccatcag ccccagcatc cgtttttcac
    42661 gcgaacagag cgggcccatt gcctgcagtt ccgtctctgc ccagcgcggc acctgatcgc
    42721 cagacttcag taccggcggg tacagcacat aagccagcca gggaaccagc agcaccagca
    42781 aaatactgag cggcaacatc ccgaggaacc agtcgcccca actcagcgtg gcgtgagatg
    42841 cgcttttcat cagtccaatt aacagcaagt ttggtgccat cgccgtcaag aaaatggcgc
    42901 tggtcacgca gtcggcaaca atccccatcc acatgatgta cgagccaatg ctgcgcgaac
    42961 tgctgtcgtt tggttgtgat tgatagagcg gtggcaggtt acggatgatg ggatagataa
    43021 tccccgcacc acgcgccgag ttggacggtg ttacaggtgc gaggatcagc tcggagaaca
    43081 tcaccgcata gccgagaaac agcgtgcgat gtcccatctt tttcaccaga aacagcgcaa
    43141 tgcggcgtcc aagcccggtt ttttcatagc ctgtgccaaa cataaaggcg gcgaaaatca
    43201 gccagataac cgaattagaa aaaccggaaa ccgcccacga gagggatttt gcagtgaatt
    43261 taaagcctgg ctgggcgagc tgttcggggc tgaacagcag ccagggagag agtatggcga
    43321 tgatggagat acccaccatc gccaccacgg cacccggcac gggttcgagg atcagtccaa
    43381 cgatcacgcc agtaaaaacg gcaaagtaga gccaggtatg gttctccagc cctgcgggaa
    43441 ccggaagtag agcaataatg gcgatgaccg ccagcggcgc aagatatcgc caccattcag
    43501 tggaaggttt catcgtgtta tgcctgcgaa aaaggagagg ggtgagcctc tccgggaggg
    43561 ttatttgatg taatggacgt gctcgcagat ctcttccacg atgggatcgc ggcgttcggc
    43621 gaacagcttt ttgttttcgg ctatcaggtt gttgccgtgg gtatcaatag agacaatcag
    43681 cgggccgaac tctttgaccc ggcagaccca cagtgactcc ggcatcccga gttctgtcca
    43741 gtgcacttct tcaatctctt ctacctgggt tgccgccagc accgcgcagc ctgccgggaa
    43801 aatcacatgt agcgccttga atttctggca gccttcttcg gtcagcggcc ccataccacc
    43861 tttgccaacc accagtttca cgccggtctg ctcgataaat tcacgttcaa aactttccat
    43921 acgcatactg gttgtcgggc caacggaaac catctcccat ttatcgccgt ttttgcgcac
    43981 gatggggcca gcgtggaaaa tcgctttgcc gttgagatcg taagggatcg gacgtttcag
    44041 ttcgatcaag cggcggtgac aaacgtcacg gcaggtcacc agcgtaccgg tcaggtagat
    44101 cacatcgccg acgcgaatat cttgcagatc ttcagctttg atcggggttg tcaggatctt
    44161 tttcataacg cgctccgggt gtgagacaga ttttcaaagg tgagatcggc atgaaccagc
    44221 agtgtgccgc gacgatgcgc ccagcagcct gtagaaacag caacgccgat ggttgacgga
    44281 tggcgggcgg cagattcgat atgcacgccc atcactgaac tgttgccagt cagcccttgt
    44341 gggccaattc ccagacggtt gagtccttct tccaggcgta gctccagctc tgccgctttt
    44401 ggattgggat ggcggctgcc aatcgggcgc aaaatggctt ttcgcgagag cacggcggcg
    44461 gtttccaccg aggtggcgat gcccacgccc accagtaccg gtggacaggc gtttacggcg
    44521 agggtggaga tattttcgaa gacgaatttc actacgcctt cgtagccttc tgacggcatt
    44581 aacactttcg agcggccagg tagcgtgcag ccgccgcctg ccatgtaaac ttcgatttcc
    44641 gcatcgtcat tgtcggggat gatgtcccag gtgacccacg gtacgccgct accggtattt
    44701 ttgccggtgt ttacttcgtc aaaaatttct accgcattgt gacgtagtgg cgctttgacg
    44761 gttgcctctt ccacggcttg tttgagtatg ctttgcagct cgccaagcag tgggaagcgg
    44821 gaaccgactt taacgaagaa cataatctcc ccggtgtcct gacaggcagg acgattcagg
    44881 tcaatcgctt tttgcatgtt gtcgaacatc gtatggtaga taattttccc catcgacgac
    44941 gtttcggcat cctttagctg ttttagttta tccaccacgt catcaggcat tcgggtagaa
    45001 atcatggcgg taaagttagc gacaatctct gtcaacttat tcactgcctg ttgcttatta
    45061 ctttcgctca tcatggcaac tccagttttt gtatttgtct ggaaaaattc accgccacaa
    45121 actaccacta aaaatgtggt tttatatttt ttgccaccgt gaatatgtaa ttaacagttc
    45181 gtgaatcaac gcgaaaataa gaatgaatat tgcgccagag cagggaatgg caatgttttg
    45241 cgaaatacac tgcgcttatc acaactgcgg ataattaacg atgctgaata gctggccttt
    45301 agccaaagac ttgcaggtac tggtagaaat cgtccacagc gggagtttta gcgccgcagc
    45361 ggcgacgctt gggcagacgc ctgcatttgt caccaagcgg atccaaatcc ttgaaaatac
    45421 gctggcaaca acgctgctga accgctccgc tcgcggcgtg gcgctgactg aaagtggcca
    45481 acgttgttac gaacatgcgc tggaaatcct cacccaatat cagcgactgg tcgatgacgt
    45541 cacgcaaatc aaaacgcgcc cggaggggat gattcgtatt ggctgtagtt ttggttttgg
    45601 gcgcagccat attgcgccag ccattaccga acttatgcgc aattaccctg agttacaggt
    45661 gcattttgaa ttgttcgatc ggcaaattga tttagtgcag gataatattg atctggatat
    45721 tcgtattaat gacgaaattc ctgattatta tattgcgcat ctgttaacga aaaataaaag
    45781 aatattatgc gcagcacctg agtatctgca aaaatatccg cagccacaat cattacagga
    45841 attaagtcgt catgactgtc tggtgaccaa agagcgcgat atgacccacg gaatatggga
    45901 gttggggaac ggtcaggaga aaaaatcggt gaaggttagc gggcatcttt cctccaatag
    45961 cggcgagata gtgttgcaat gggcgctgga gggcaaaggg attatgctgc gttccgagtg
    46021 ggatatgttg ccgtttctgg agagtggcaa actggtgcaa gtattgccgg agtatgcaca
    46081 aagcgccaat atctgggctg tttaccggga gccgctctat cgcagcatga aattacgtgt
    46141 ctgcgtggaa tttctggcgg catggtgcca gcaacggctg ggcaagcccg atgaaggcta
    46201 tcaggtcatg tagatccacc agaaatcact cgggatcctt ttcgcgcttt cttttgaatt
    46261 tcgtccagat ttttgtctcc tgacgacgcc acagacgctg gatgttgtca tgatgacgca
    46321 gcaggatcag gcaagagagc atcgaaaccg ggaaggtgaa ttgtggctta aaccaccata
    46381 cataaaacgg agcaatcagt gcactgacaa tcgctcccag cgacgagtat ccgctcaata
    46441 gcacggtcag taaccaggtt cccgccatta ctccggtgag atcccagcca atgggtgcga
    46501 tggcaccaaa agcggtagca acgccttttc ctcctttaaa tccgaagaaa acgggccaga
    46561 tgtgtccaag acaggcggcg atggcaatta agcctagcca gaaggggctg acacctaatt
    46621 catacgcgcc ccagacgggc aacattcctt tcagaacgtc gaaaatcagt actgctacgg
    46681 ctgctccctt gccaccgata cgtaacacat tggttgcgcc tggattgccg gagccgctgg
    46741 ttcgcggatc gggcagccca cacaagcggc aaaccagaat ggcactggaa atggagccgc
    46801 agaggtacgc gatgaggatc attccaggcg cgattgcact cataagctgt tccgttttga
    46861 aaattcgtgt tcaacgatga atctgtggat aatacgcaca tttcgccgga agtggtatcc
    46921 ggttagccaa aaagcaggca ggacgtgatg gatattgtat ttatagagca actttcggta
    46981 atcaccacta ttggtgttta cgactgggaa cagaccatcg aacagaagtt agtgttcgat
    47041 atcgaaatgg catgggataa ccgtaaagcg gcgaaaagtg atgatgtggc ggattgcctc
    47101 agttacgctg acattgcaga aacggtggtc agccacgtcg agggggcgcg ttttgcgctg
    47161 gtggaacgcg tggctgaaga ggtggcggag ctgctgttag cacgcttcaa ctcgccgtgg
    47221 gtgcgtatca aactcagcaa gccaggcgca gtggcgcggg cggcgaatgt tggcgtaatc
    47281 attgagcgtg gcaataatct gaaagaaaat aattaatttt acagctgtta aaccaaacgg
    47341 ttataacctg gtcatacgca gtagtccgga caagcggtac attttaataa tttaggggtt
    47401 tattgatgag cgatatgcac tcgctgctga tagcggcaat attgggtgtg gtcgaaggat
    47461 tgacagaatt tctgccggta tccagcacgg gccatatgat tattgtcggt cacttgttgg
    47521 ggttcgaggg cgacacggcg aaaacctttg aagttgtgat ccagttagga tcaattctgg
    47581 cggtagtagt gatgttctgg cggcgtctgt ttggcctgat tggcatccac tttggccgcc
    47641 cgttgcagca cgaaggagaa agcaaaggtc gtttaacgct gatccacatt ttgctgggga
    47701 tgattccggc ggtggtactg gggctgttgt tccacgacac gattaagtca ttgtttaacc
    47761 cgataaatgt gatgtatgca ctggtcgttg gcggtttgtt gctgattgcc gccgaatgcc
    47821 tgaagccgaa agagccgcgt gcgccgggtc ttgatgatat gacctatcgt caggcgttta
    47881 tgattggctg tttccagtgt ctggcgctgt ggcctggttt ctcccgttcc ggggccacca
    47941 tttcaggtgg gatgctgatg ggcgtgagcc gttacgctgc ttccgagttc tcgttcctgc
    48001 tggcggtacc gatgatgatg ggcgcaacgg cgctcgatct ctacaaaagc tggggcttcc
    48061 tgacaaccgg cgatatcccg atgtttgccg ttgggtttat caccgctttt gtggtggcgc
    48121 tgatagcgat taaaaccttc ctgcaattga ttaagcgcat ttcgtttatc ccgttcgcca
    48181 tttatcgctt tattgtggcg gctgcggtgt acgtcgtgtt cttttgattg agaaaaggtt
    48241 cgggagcagg cctggttttc tccctcgctc tgtagggaga gggccggggt gggggtgatt
    48301 gttcgcaccg gtgctggtct gttcccctca ccctaaccct ctccccgaag gggcgagggg
    48361 atggttcgtg ttaacgttta gttttatact cagtcaggct ttgggcaacg ttgttccttc
    48421 caactggcta tcgccgcaat ccgccgtcgg gtcagctcct cgcgaatctc cacaccttta
    48481 aatcccgctt caacgaccgc ttttgtcggc actgactgcg ccacttccca ggcttcgcgc
    48541 aaccaacggc cttgcgggta gtccgctgat tcaaaaccgg ttctgccgcg cacgtcagcc
    48601 tcgctggtca gcgccagttg ctcgacacgc tgcggtttac gccaggcatc gatggaatca
    48661 aacaatttga cgatagtttt tgggttcagc attgggaagg tgtggatgag atcgtgaaac
    48721 tcagccacca gtctggctaa atcgcgaatt tcatttggca cgcgcagacg ctggcagagt
    48781 tgttccacta atttcacacc cgccggaccg tgaccatgat gacgcggcca aagttctggc
    48841 ggcgtcagtc ctttaccgag atcgtggcat aaagttgcga aacggacatc gacctgcgga
    48901 ctcagcatcg ccgccattga gagcgtcatt aaggtatgaa tacccgtgtc gatttccgga
    48961 tgccacctgg caggggccgg aacgccaaac agtgcgtcaa tttccgggaa taaaacgcgc
    49021 agtgcgccac aatcgcgcag tacctggaag aacacctgtg gattgcgggt ggtgagggcg
    49081 ctttccgtct ctttccatac ccgttcaggc gtcaggtgtt ccagttcacc cgcatgggtc
    49141 atctcgcgca tcagcgtcag agtttcatcg gcaatacgaa aaccgaggtg ggcataacgc
    49201 gcagcaaaac gcgccacgcg cagaacgcgt aacggatctt cgccaaaagc gggggaaaca
    49261 tggcgcaaca gacgattttg cagatcgccc agaccgttgt acgggtcgat aatctcgccg
    49321 ttatcgtcct gggccagcgc attaatggtc agatcgcgac gcttaagatc atcttccagc
    49381 gtgacatccg gtgcggcata gcaagtaaaa ccggtgtaac cggaaccgga tttccgttcg
    49441 gtacgtgcca gcgcatactc ttcatgcgtt tgcggatgca gaaacacagg aaaatcgcgg
    49501 cctacctgct ggtagcccgc gtcgagcatc tcctgtggcg tactgccgac caccacccaa
    49561 tctctgtctt tgaccggtag ccctaacaat gcatcccgaa cagcaccacc gaccagataa
    49621 atcttcacgc catcatccct tcgtcaaata cacaattcct aataataaga cagtgcaacg
    49681 aagaaggcga tttagttcat ccagcgatct ttgcgtttgc gcgttgggat caggtgtggc
    49741 agtaccagac cgagcagcaa gccaagcccc agcacgccac cgccatacat aaaccattgc
    49801 atgatgatgg tgcgctgttt gtcatccaac tgtacgctgg cggcatcgac ctttttctgc
    49861 gcgacaatca gctcgttttt caatttctga ttttcttctt ttaatccgtt gatcacgctg
    49921 tcgctctgcg ccactttttg ctgcatttct gcggtgcgct gattccaggt gttatcgata
    49981 ttggtgagtt tatcggtcag ggttttgacc tgattttcca gatctggcac acgggagcgc
    50041 aggcttggct cagtgctaag ttgtttcaac gggatccagg cggtacggcc agagctgtct
    50101 ttcacctggg cataattggt gttggcgtca gtttgtaata aggtcacttc ctcgccggcg
    50161 ttaaccgtgc ccacgaggcg ataatgatct cccggaccgc tacggaccca ggtattcagt
    50221 tcatcagaaa catagcgcgt ttcttcagcg tgtgagacgg cagtggcgct aagtgcgagt
    50281 aaagttaatc cgatcaggcg taattttggc atcaggctgt cgttattgtc atggaaagtg
    50341 gaacgatagt agtggcatca gtgtcgctac gcaaagcatt cgacatcaat cggaatcctc
    50401 tgtgtcaggt cttgccactg cttcaaactt ttacgcccgt caaattgccc gttgcatggc
    50461 aatttggcgc aaaatactat ctactgacaa aaaagatcgc attaagttcg ccgttcatcg
    50521 tcacttatgt gacataaccg ataagtaaag gccatggctc aggaaatcga attaaagttt
    50581 attgttaatc acagtgccgt tgaggcgttg cgtgaccatc tcaatacgct gggcggcgag
    50641 caccatgacc ccgtgcagtt gctgaatatt tactacgaaa cgccggataa ctggctgcgt
    50701 gggcacgata tgggcttacg tattcgtggc gaaaacggtc gctatgagat gaccatgaaa
    50761 gttgcaggaa gagtgacagg cggcttacac cagcgcccgg aatataacgt ggcgttgagc
    50821 gaaccgacgc tcgacctggc gcagttaccg acggaagtct ggccgaacgg cgaattgccc
    50881 gccgatctcg cttcccgcgt acaaccgctg ttcagcaccg atttttatcg cgaaaaatgg
    50941 ctggtggcgg tcgatgacag ccgaattgaa atcgctctcg atcaggggga ggtgaaagcg
    51001 ggggaatttg ctgaacctat ctgtgagctg gaactggaac tgcttagcgg cgacacgcgc
    51061 gcggtgctga aactggcgaa ccaactggta tcgcaaaccg gattacgcca gggcagcctg
    51121 agcaaagcgg cgcgtggcta tcatctggcg cagggcaatc cggcgcgtga aatcaaaccg
    51181 accaccattt tgcatgttgc ggcaaaagcc gatgtggaac aggggctgga agcggcgttc
    51241 gagctggcgt tagcgcaatg gcagtatcat gaagaactgt gggtacgcgg caacgatgcg
    51301 gcgaaagagc aggtgctggc agccattggc cttgttcgcc atgcactgat gctgttcggt
    51361 ggcattgtgc cgcgtaaagc gagcactcac ttacgtgatt tgctgactca atgcgaagcg
    51421 accatcgctt ctgcggtttc tgccgtgacg gcggtctact ctaccgaaac ggcaatggca
    51481 aagctggcgt tgaccgaatg gttggtaagc aaagcctggc agccgttttt agatgccaaa
    51541 gcgcagggta aaatcagcga ttccttcaaa cgctttgccg atatccatct ttcccgccat
    51601 gccgctgaac tgaaaagcgt tttctgccag ccgttaggcg atcgctacca tgatcagttg
    51661 ccacgcctga cgcgtgatat tgactcaata ctgctgctgg caggttacta tgatcctgtc
    51721 gtcgcgcaag cctggctgga gaactggcag gggctgcgtc acgctattgc gaccgggcaa
    51781 cgcattgaaa ttgaacattt ccgtaatgag gcaaacaatc aggaaccgtt ctggttgcac
    51841 agcggaaaac gttaatcagg caaggataaa atcgcttatg aagccgctct cttcaccgtt
    51901 acagcagtac tggcagaccg ttgttgagcg gctgccagag cctttagccg aggaatcact
    51961 tagcgcacag gcgaagtcag tacttacttt tagtgatttt gtgcaggaca gcgtgattgt
    52021 gcatccagag tggctgacgg aactggaaag ccaaccgccg caggccgacg aatggcagca
    52081 ttacgcggca tggttgcagg aggcgctcag taatgtgagt gacgaagtcg ggttaatgcg
    52141 cgagctgcgg ctattccggc ggcgcattat ggtgcgcatc gcctgggcgc aaacgctggc
    52201 tttgattact gaagagagca tattgcagca gctcagccat ctggcggaga cgctgattgt
    52261 cgccgcgcgt gactggctgt atgacgcttg ctgccgcgag tggggaacgc cgtgcaatgc
    52321 gcagggcgaa gcgcaaccgc tgctgatttt aggcatgggt aagctgggcg gtggggaact
    52381 gaatttctcc tcagatatcg atctgatttt tgcctggccg gaacatggtt gtacgcaggg
    52441 cggacgccgg gaactggata acgcgcagtt ttttacccgc atggggcagc ggctgattaa
    52501 agtgttggat caaccaacgc aggatggctt cgtctatcgc gtggatatgc ggctgcgtcc
    52561 gtttggcgaa agtggcccgc tggtgctgag ctttgccgcg ttggaggatt attaccagga
    52621 gcaggggcgc gactgggagc gttacgcgat ggtcaaggcg cggattatgg gcgatagcga
    52681 aggcgtctat gctaacgagt tgcgtgcgat gctgcgcccg tttgttttcc gtcgttacat
    52741 cgatttcagc gtgattcagt cgctgcgcaa catgaaaggg atgattgccc gtgaagtgcg
    52801 tcgacgtggt ttgaccgaca atatcaaact cggcgcaggc ggcattcgcg aaattgaatt
    52861 tatcgttcag gtgttccagc tcattcgcgg tgggcgcgaa ccgtcgctgc agtcgcgctc
    52921 tttactgcca acgctcagcg tcattgccgc gctgcatctg ctttctgaaa acgatgctga
    52981 acaattgcga gtggcgtatc tgttcctgcg gcgtctggaa aacctgctgc aaagcattaa
    53041 cgacgaacaa acccagacgc ttccttctga tgagcttaac cgtgcgcggc tggcgtgggc
    53101 gatggacttt gctgactggc cgcaactgac cggggcgctg accgcacata tgaccaatgt
    53161 gcgccgggtg tttaatgaat tgattggcga cgacgaaagt gaaactcagg aagagtcgct
    53221 gtcggaacag tggcgtgagc tgtggcagga tgcgttgcag gaagatgaca ctacgccagt
    53281 gctggcgcat cttagcgagg atgatcgcaa acaggtgcta acgctgattg ccgatttccg
    53341 caaagagctg gataagcgca ccatcgggcc gcgaggacgt caggtgctcg accatctgat
    53401 gccgcatctg ctaagtgatg tctgtgcgcg tgaagacgct gccgttacgc tgtcgcgcat
    53461 taccgccttg ctggtgggga ttgttacccg caccacctat ttagaattgc tcagtgaatt
    53521 ccccgcggcg cttaaacatt tgatttctct gtgtgccgcg tcgccgatga ttgccagcca
    53581 actggcgcgt tatccattat tgctggatga attgctcgat ccaaacaccc tttaccagcc
    53641 gacggcgacc gatgcctacc gcgatgagtt gcgccagtat ttgctgcgcg tgccggaaga
    53701 tgacgaagag caacagcttg aggcgctgcg tcagttcaaa caggcgcagc tgttacgcat
    53761 cgccgcagcg gatatcgctg gtacgctacc ggtgatgaaa gtgagcgatc acttaacctg
    53821 gctggcagag gctatgatag atgccgtcgt tcagcaggcg tgggttcaaa tggtggcccg
    53881 ctacggtaag ccaaatcacc tcaacgatcg cgaaggccgt ggttttgcgg tggtcggcta
    53941 cggcaagctg ggcggctggg agttaggcta cagttccgat cttgacctga tcttcctcca
    54001 tgattgccca atggatgcga tgactgacgg cgagcgggaa atcgacgggc gacagtttta
    54061 tctgcgtctg gcgcaacgca ttatgcatct gttcagtacg cgtacctctt ccggcatttt
    54121 gtatgaagtg gatgcacggc tacgcccgtc cggggccgcg ggaatgctgg tgacatccgc
    54181 agaagcattt gccgattatc agaaaaacga ggcctggacg tgggaacatc aggcgctggt
    54241 gcgtgcgcgg gtagtgtacg gcgatccgca gctcaccgcg cactttgacg cggtgcgtcg
    54301 cgagattatg acgctgccgc gtgaaggtaa aactctgcaa acggaagtgc gggaaatgcg
    54361 cgagaaaatg cgcgctcatc tcggcaataa acatcgcgat cgctttgata tcaaagctga
    54421 tgaaggcgga attaccgata tcgaatttat tacccaatat ctggtgttgc gctacgctca
    54481 tgaaaaaccg aagttaacgc gctggtcaga caacgtgcgc attctggaac tactggcgca
    54541 aaacgacatt atggaagagc aggaagcgat ggcgctgacc cgtgcttata ctacgctgcg
    54601 cgatgaactt catcatctgg cattacagga attgccgggc catgtgccgg aggattgctt
    54661 caccgcagag cgtgaactgg tgcgggcaag ctggcagaag tggctggtgg aagaatgaag
    54721 tatggtatta tcgcgcgcaa attttgaatc tctcaggaga caggaatgaa agtaacgctg
    54781 ccagagtttg aacgtgcagg agtgatggtg gttggtgatg tgatgctgga tcgttactgg
    54841 tacggtccca ccagccgtat ctcgccggaa gcgccggtgc ccgtggttaa agtcaatacc
    54901 atcgaagaac gtccgggcgg cgcggctaac gtggcaatga acatcgcttc tctcggtgcc
    54961 aatgctcgcc tggtcgggct gacgggcatt gacgatgcgg cgcgtgcgct gagtaaatct
    55021 ctggccgacg tcaacgtcaa atgcgacttc gtttctgtac cgacgcatcc gactatcacc
    55081 aaattacggg tactttcccg caaccaacag ctgatccgcc tggattttga agaaggtttc
    55141 gaaggtgttg atccgcagcc gctgcacgag cggattaatc aggcgctgag ttcgattggc
    55201 gcgctggtgc tttctgacta cgccaaaggt gcgctggcaa gcgtacagca gatgatccaa
    55261 ctggcgcgta aagcgggcgt tccggtgctg attgatccaa aaggtaccga ttttgagcgc
    55321 taccgcggcg ctacgctgtt aacgccgaat ctctcggaat ttgaagctgt tgtcggtaaa
    55381 tgtaagaccg aagaagagat tgttgagcgc ggcatgaaac tgattgccga ttacgaactc
    55441 tcggctctgt tagtgacccg ttccgaacag ggtatgtcgc tgctgcaacc gggtaaagcg
    55501 ccgctgcata tgccaaccca ggcgcaggaa gtgtatgacg ttaccggtgc gggcgacacg
    55561 gtgattggcg tcctggcggc aacgctggca gcgggtaatt cgctggaaga agcctgcttc
    55621 tttgccaatg cggcggctgg cgtggtggtc ggcaaactgg gaacctccac ggtttcgccg
    55681 atcgagctgg aaaatgcagt gcgtgggcgc gcagataccg gctttggtgt gatgaccgaa
    55741 gaggaactga agcttgctgt agcggcagcg cgtaaacgcg gcgaaaaggt ggtaatgacc
    55801 aacggtgtct ttgacatcct gcacgccggg cacgtctcct atctggcaaa tgctcgcaaa
    55861 ctgggtgacc gtctgattgt cgctgtgaac agcgatgcct ccaccaaacg gctgaaaggg
    55921 gattcccgcc cggtaaaccc actcgagcag cgtatgattg tgctgggcgc actggaagcg
    55981 gtcgactggg tagtgtcgtt tgaagaagac acgccgcagc gtctgatcgc cgggatcctg
    56041 ccagatctgc tggtgaaagg cggcgactat aaaccagaag aaattgccgg gagtaaagaa
    56101 gtctgggcca acggcggcga agtgctggtg ctcaacttcg aagacggttg ctcgaccact
    56161 aacatcatca agaagatcca acaggataaa aaaggctaac cggaaagcgg ttcacagatc
    56221 tcgcttcgta gcaggcaggc ctattgacgc tgttgttttt tcaacctaaa gtaaaggaac
    56281 aagggtaagg gaggatttct cccccctctg atcagttgtt agtaagtcgg gaaacttaac
    56341 agtaacaaca caaccagtat gatgacgaac ttcatcataa ccctttcctt ctataaggcc
    56401 ccttcctcgg gaggggcttt cccgtttcag ccccttgctg actccccgat tgttgatgag
    56461 cgccggaccc cgcgcaacgc tttccctgaa gcagttttgc cttccccgag cggtcacgca
    56521 aaacgctgca acgtcctgag catttgcacc ttttagcgga acgcagatat aaaaaatccc
    56581 cggctttttg ggccagggat atgtgttaat gaaaccttct tgacgctgat tttttttcaa
    56641 cctaaagtaa aggaacaagg gtgagggagg atttctcccc cctctgattg gctgttaata
    56701 agctgcgaaa cttacgagta acaacacaat cagtatgatg acgagcttca tcataaccct
    56761 ttccttctgt aaggcccctt cctcgggagg ggctttcccg tttcagccct ttgctgactc
    56821 cccgattgtt gatgagcgcc ggacctcgcg caacgctttc ccagaggcag ttttgccttc
    56881 cccgagcggt cacgcaaaac gttgcaacga cctgatcatt tgcagttttt agcggaacgc
    56941 agatataaaa aatccccggc tttttgtgcc agggacgttc atagctgaaa atttattcta
    57001 cgttttcggc gacgggagtt gttgaggtta agggtgaagt caatgccgcc agtgagccgc
    57061 ctgaaacgcc aatttcattg agcaaggagt caatcagcgg tgcctgtgtg cggtaagaga
    57121 gagcggctga taatgcttgt tccgccaggt ttccgccccc cacattaccc gtgtttgcat
    57181 cacccgcagc gctgccacga ttcagaccat cgacctgaat aatcttgata ccgtcaatag
    57241 atttcatcgg ctcaacggat ttttctatta ccgcaggtag cgcctgcaac aaggccagtt
    57301 tgaatttaag gctggtttgt tcatcagaaa gtacgttgat agcatcgttc agcgcacgtt
    57361 gtgcttctgc ttccgccaga ccctttttac gtgtagcttc ggctaactca acgatagccg
    57421 ccgcctgcat ctctgcggct tctttttctg ctttcgcccg cacggtcagt tcaaccgctt
    57481 tggtttctgc atcctgcgcg gcagcgatta gggcaacttg tttagcacga tcggcttctg
    57541 cggtctggcg agtggtttct acgttttgtt gcgcacttac tgcttctgcg agtgcaaggt
    57601 tagcacgcgc ttctgcctgg gactgttgtt ccgatttagc ggcaatagcg atcgatttcg
    57661 tctggttggc gatttcggtg acctgctgtt gttcgatctc tttaatacga acttcacgtt
    57721 cagcctcaac ctttcttgag cggacggcct gctcgcgctc gatctccgtt tcctgaattt
    57781 gtcgttcagc cagaattcgc gtctgctctg cttcacgacg acgttcagct tcaaaagccg
    57841 caatacgtgc attctgttcg gcagtacggg ttttaacctg ctgctcctgc tcaagcgtca
    57901 taaacgcttc ttgttgttca atctccaact tgcgcgaaag tgcatcacgg tttttctcac
    57961 gcaccgcaac ttctacatcc tgttcaactt cgttacgttc gcgacgacgg cgctccgtct
    58021 cctgagtcag tttggttaaa ccttcggcgt caaaggcatt gttcggattg aaatgttctt
    58081 tcgaggtctg gttaaagttg gtaagtgaaa cgctttccag ctcaagaccg tttttcgaca
    58141 ggtcttctgc gacagtattt tgtactccct gcacgaagtt ctcgcgggta tcctgtaact
    58201 catgcatggt catttgtgca gctgttgcac ggagggcatc gacaaattta tcttcaacca
    58261 acatacgtaa gtcttctggt gatagcgtgc gttgccccaa cgtctgcgcc gcagtggcga
    58321 tgccttctac agacggtttt acccgtacaa agaaagcgac tactacatca acacgcatac
    58381 gatctttcgt aatcaggcta tcaatggttg agcggctgac ttccagcttc agagtattca
    58441 tattgatggg gattatttca tgaaagatcg gcatcacgat tgcgccaccg ctcatcacca
    58501 ctttttgccc acctaaacca gtacgaacaa aagcttgctc tgccgaagcg cgacgataga
    58561 gcctggcgaa aataattcca ataataaaca gaatgcatac ggcaataatc gcggtaaaca
    58621 tccaggaggg cacagaatta acaatatcat ccattattaa atttcctttt gattaataaa
    58681 ttacaatatt tgtggccagg gattgttttc cgccaaatat cgcgttgcag aaagtcggca
    58741 aataattaac actttgtctc ctttagtgaa aaattttcct tcttcaggct ccagtagtaa
    58801 ataatgtatt tggccaaatt gatcggtgag ttttccttcg cagggattac ctgaagtggc
    58861 ttgatgaccg gtaattaatg ccatgctacc aatatattct tcttctgtaa tagctgaact
    58921 atggtcgcgt ggaatccagg gcgcaactat tttaccggta taatgcaccg caataatcgt
    58981 aaacagtaaa ctgacaggaa ccacgaacag gttcgacagt ggtgattgcc agaccatgat
    59041 gcaggcatgc tgcaacagga tgccaataag accaaaaaaa ccagccagca agcagagaac
    59101 gacgagagct ggcaatcttc cgatattgag ataatgaagt gcctggctaa tatgacctgt
    59161 ggttatggaa tcataatggt caagatgtgc atcaagagca ccggagagca tgtgaccgca
    59221 gataagcgct aaaatttcta aaaggccgat caacagtaca aaggaaatag cgaaaagata
    59281 aggggtatta tagtcggcga ataaaatcat atgtcactcc aatgtccatt tagtgacgca
    59341 atatttactt tgggatagtt tccttgctta catttatctt tgttaataat aacacatgtt
    59401 agagaagttc tggaagagaa agttttttaa tatggttttt tatttttcac taaaaagtgt
    59461 gatcggggac aatatattta cgcacgttat gtttaaaggc actacactga ttggggaata
    59521 ctgaaatcag aaaaagcata tggccttaaa aggtatgcga taaccggagg atgtgcttat
    59581 ggatcatagt cttaattctt taaataattt cgatttcctg gcgcgtagtt ttgccagaat
    59641 gcacgcagaa ggtcgcccgg tcgatattct tgccgttact ggtaacatgg atgaagaaca
    59701 tagaacctgg ttttgcgcac gttatgcctg gtattgtcaa cagatgatgc aggcaagaga
    59761 gctggagtta gagcactgat ataacgggcc tgatggcccg ttttagtgtt tgtattagat
    59821 gctagttata ggtgattttg aggatgacgt ctttactaaa cggtccctca acaacagtct
    59881 ctgccggatt cgcactaagt tctgccctga atggtgcggt gaccgaaggt gcactagacg
    59941 atgaaaaaga agcaaattgt gagaagcggt taatttccgt tgctgttcca tctttatgaa
    60001 atatcttcaa tagcagtcca ttacccatat ccagatggct ataatcactc aaaatatccg
    60061 tagtgaaaaa gctccctaaa atattgaatt gctcagtaca ggccgcacca ggatcttttg
    60121 tcatgactac actaaacgtc tcactaacgc tggtattttt aattgttcgg gaatttattt
    60181 taccaaagtc aacaacgcca tcagctggtt ccagtgcgac attaacaaag cagtcaagga
    60241 catgaatatt atttaatcca cgaatcctga aggtcaaatt tttgtctact tctatagctc
    60301 ctgcgccact cataccttta aactctagag cgatatattc atcaggtaac accaggtttt
    60361 tattaactct attggcattt tttgctaatt taatatagag ttgtacgcga gctggaaagg
    60421 ttactgataa ttgaggctca ggacctccac tacagacagc ggggttttta tagtgattat
    60481 taaaggtacc cgctcctttt atatcaatgc attctggtgc tgcgatagca ttaggggcag
    60541 tcgaatcata atcaactcca ttgtatgtta cgccaaaaat ataggagttc tgattataaa
    60601 agtcctgacc gcctggtaaa aacatcatta tattagtcca ggctgatggg tattcttctc
    60661 caggtgatgg ggcaggtaat gcattattac agaagacatt cataaaatac tcactgcttt
    60721 gccagatctt atcacctttt ttaccattac tggggataga aattcttggt acgtaaccaa
    60781 tgactacggt atttccccct tcatgttcag catagcagtc cattgcccat acaggtaatg
    60841 cactaaaa
//
LOCUS       DAPGUL010000013        60739 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.013, whole genome shotgun sequence.
ACCESSION   DAPGUL010000013 DAPGUL010000000
VERSION     DAPGUL010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 60739)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60739)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60739
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.013"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..767
                     /gene="ynaI"
                     /locus_tag="RHX21_000954"
     CDS             <1..767
                     /gene="ynaI"
                     /locus_tag="RHX21_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="low conductance mechanosensitive channel YnaI"
                     /protein_id="HDV1986179.1"
                     /translation="LTIKLFLLINQFEKQQIKKGRDITSARIMSRIIKITIIVVLVLL
                     YGEHFGMSLSGLLTFGGIGGLAVGMAGKDILSNFFSGIMLYFDRPFSIGDWIRSPDRN
                     IEGTVAEIGWRITKITTFDNRPLYVPNSLFSSISVENPGRMTNRRITTTIGLRYEDAA
                     KVGVIVEAVREMLKNHPAIDQRQTLLVYFNQFADSSLNIMVYCFTKTTVWAEWLAAQQ
                     DVYLKIIDIVQSHGADFAFPSQTLYMDNITPPEQGR"
     gene            complement(818..2431)
                     /gene="mppA"
                     /locus_tag="RHX21_000955"
     CDS             complement(818..2431)
                     /gene="mppA"
                     /locus_tag="RHX21_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415845.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide ABC transporter
                     substrate-binding protein MppA"
                     /protein_id="HDV1986180.1"
                     /translation="MKHSVSVTCCALLVSSISLSYAAEVPSGTVLAEKQELVRHIKDE
                     PASLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIVPGVATQWKSNDNRIWTFTLRDNA
                     KWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGINNAQAIIDGKATPDQLGVTA
                     VDAHTLKIQLDKPLPWFVNLTANFAFFPVQKANVESGKEWTKPGNLIGNGAYVLKDRV
                     VNEKLVVVPNTHYWDNAKTVLQKVTFLPINQESAATKRYLAGDIDITESFPKNMYQKL
                     LKDIPGQVYTPPQLGTYYYAFNTQKGPTADQRVRLALSMTIDRRLMTEKVLGTGEKPA
                     WHFTPDVTAGFTPEPSPFEQMSQEELNAQAKTLLSAAGYGPQKPLKLTLLYNTSENHQ
                     KIAIAVASMWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLTLL
                     TSTHSGNISRFNNPAYDKVLAQASTENTVKARNADYNAAEKILMEQAPIAPIYQYTNG
                     RLIKPWLKGYPINNPEDVAYSRTMYIVKH"
     gene            complement(2768..3667)
                     /gene="pgrR"
                     /locus_tag="RHX21_000956"
     CDS             complement(2768..3667)
                     /gene="pgrR"
                     /locus_tag="RHX21_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator PgrR"
                     /protein_id="HDV1986181.1"
                     /translation="MKREEIADLMAFVVVAEERSFTRAAARLSMAQSALSQIVRRIEE
                     RLGLRLLTRTTRSVVPTEAGEHLLSVLGPMLHDIDSALASLSELQNRPSGTIRITTVE
                     HAAKTILLPAMRTFLKSHPEIDIQLTIDYGLTDVVSERFDAGVRLGGEMDKDMIAIRI
                     GPDIPMAIVGSPDYFSRRSVPTSVSQLIDHQAINLYLPTSGTANRWRLIRGGREVRVR
                     MEGQLLLNTIDLIIDAAIDGHGLAYLPYDQVERAIKEKKLIRVLDKFTPDLPGYHLYY
                     PHRRHAGSAFSLFIDRLKYKGAV"
     gene            3805..4725
                     /locus_tag="RHX21_000957"
     CDS             3805..4725
                     /locus_tag="RHX21_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415843.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDV1986182.1"
                     /translation="MMNNKVSFTNSNNPTISLSAVIYFPPKFDETRQYQAIVVSHPGG
                     GVKEQTAGTYAKKLAEKGFVTIAYDASYQGESGGEPRQLENPYIRTEDISAVIDYLTT
                     LSYVDNTRIGAMGICAGAGYTANAAIQDRRIKAIGTVSAVNIGSMFRNGWENNVKSID
                     ALPYVEAGSNARTSDISSGEYAVMPLAPMKESDAPNEELRQAWEYYHTPRAQYPTAPG
                     YATLRSLNQIITYDAYHMAEVYLTQPMQIVAGSQAGSKWMSDDLYDRASSQDKRYHIV
                     EGANHMDLYDGKAYVAEAISVLAPFFEETL"
     gene            4796..4933
                     /locus_tag="RHX21_000958"
                     /pseudo
     CDS             4796..4933
                     /locus_tag="RHX21_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707232.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent dehydratase"
     gene            5060..5788
                     /gene="mpaA"
                     /locus_tag="RHX21_000959"
     CDS             5060..5788
                     /gene="mpaA"
                     /locus_tag="RHX21_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415842.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide amidase MpaA"
                     /protein_id="HDV1986183.1"
                     /translation="MTVTRPRAERGAFPPGTEHYGRSLLGAPLIWFPAPAASRESGLI
                     LAGTHGDENSSVVTLSCALRTLTPSLRRHHVVLCVNPDGCQLGLRANANGVDLNRNFP
                     AANWKEGETVYRWNSAAEERDVVLLTGDKPGSEPETLALCQLIHRIQPAWVVSFHDPL
                     ACIEDPRHSELGEWLAQAFELPLVTSVGYETPGSFGSWCADLNLHCITAEFPPISSDE
                     ASEKYLFAMANLLRWHPKDAIRPS"
     gene            complement(5763..6728)
                     /gene="ycjG"
                     /locus_tag="RHX21_000960"
     CDS             complement(5763..6728)
                     /gene="ycjG"
                     /locus_tag="RHX21_000960"
                     /EC_number="5.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707230.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-Ala-D/L-Glu epimerase"
                     /protein_id="HDV1986184.1"
                     /translation="MRTVKVFEEAWPLHTPFVIARGSRSEAHVVVVELEEEGIKGTGE
                     CTPYPRYGESDASVMAQIMSVVPQLEKGLTREELQKILPAGAARNALDCALWDLAARK
                     QQQSLADLIGITLPGTVTTAQTVVIGTPDQMANSASTLWQAGAKLLKVKLDNHLISER
                     MVAIRTAVPDATLIVDANESWRAEGLAARCQLLADLGVAMLEQPLPAQDDAALENFIH
                     PLPICADESCHTRSNLKALKGRYEMVNIKLDKTGGLTEALALATEARAQGFSLMLGCM
                     LCTSRAISAALPLVPQVSFADLDGPTWLAVDVEPALQFTTGELHL"
     gene            6847..7353
                     /gene="tpx"
                     /locus_tag="RHX21_000961"
     CDS             6847..7353
                     /gene="tpx"
                     /locus_tag="RHX21_000961"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HDV1986185.1"
                     /translation="MSQTVHFQGNPVTVANSIPQAGSKAQTFTLVAKDLSDVTLGQFA
                     GKRKVLNIFPSIDTGVCAVSVRKFNQLATEIDNTVVLCISADLPFAQSRFCGAEGLNN
                     VITLSTFRNAEFLQAYGVAIADGPLKGLAARAVVVIDENDNVIFSQLVDEITTEPDYE
                     AALAVLKA"
     gene            complement(7397..8938)
                     /gene="tyrR"
                     /locus_tag="RHX21_000962"
     CDS             complement(7397..8938)
                     /gene="tyrR"
                     /locus_tag="RHX21_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707228.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator TyrR"
                     /protein_id="HDV1986186.1"
                     /translation="MRLEVFCEDRLGLTRELLDLLVLRGIDLRGIEIDPIGRIYLNFA
                     ELEFESFSSLMAEIRRIAGVTDVRTVPWMPSEREHLALSALLEALPEPVLSVDMKSKV
                     DMANPASCQLFGQKLDRLRNHTAAQLINGFNFLRWLESEPQDSHNEHVVINGQNFLME
                     ITPVYLQDENDQHVLTGAVVMLRSTIRMGRQLQNVAAQDVSAFSQIVAVSPKMKHVVE
                     QAQKLAMLSAPLLITGDTGTGKDLFAYACHQASPRAGKPYLALNCASIPEDAVESELF
                     GHAPEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEVHVDVR
                     VICATQKNLVELVQKGVFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQ
                     GVPRPKLAADLNTVLTRYAWPGNVRQLKNAIYRALTQLDGYELRPQDILLPDYDAATV
                     AVGEDAMEGSLDEITSRFERSVLTQLYRNYPSTRKLAKRLGVSHTAIANKLREYGLSQ
                     KKNEE"
     gene            complement(9086..10147)
                     /locus_tag="RHX21_000963"
     CDS             complement(9086..10147)
                     /locus_tag="RHX21_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01620 family protein"
                     /protein_id="HDV1986187.1"
                     /translation="MTEPLKPRIDFDGPLEVDQNPKFRAQQTFDENQAQNFAPATLDE
                     APEEEGQVEAVMDAALRPKRSLWRKMVMGGLALFGASVVGQGVQWTMNAWQTQDWVAL
                     GGCAAGALIIGAGVGSVVTEWRRLWRLRQRAHERDEARDLLHSHGTGKGRAFCEKLAQ
                     QAGIDQSHPALQRWYASIHETQNDREVVSLYAHLVQPVLDAQARREISRSAAESTLMI
                     AVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFKLVLLNIAFAGASELVR
                     EVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWIDDDKPRLGDFRR
                     QLIGQVKETLQKGKTPSEK"
     gene            complement(10144..11541)
                     /locus_tag="RHX21_000964"
     CDS             complement(10144..11541)
                     /locus_tag="RHX21_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcjX family protein"
                     /protein_id="HDV1986188.1"
                     /translation="MKRLKNELNALVNRGVDRHLRLAVTGLSRSGKTAFITAMVNQLL
                     NIHAGARLPLLSAVREERLLGVKRIPQRDFGIPRFTYDEGLAQLYGDPPAWPTPTRGV
                     SEIRLALRFKSNDSLLRHFKDTSTLYLEIVDYPGEWLLDLPMLAQDYLSWSRQMTGLL
                     NGQRGEWSVKWRMMCEGLDPLAPADENRLADIAAAWTDYLHHCKQQGLHFIQPGRFVL
                     PGDMAGAPALQFFPWPDVDAWGESKLAQADKHTNAGMLRERFNYYCEKVVKGFYKNHF
                     LRFDRQIVLVDCLQPLNSGPQAFNDMRLALTQLMQSFHYGQRTLFRRLFSPVIDKLLF
                     AATKADHVTIDQHANMVSLLQQLIQDAWQNAAFEGISMDCLGLASVQATTSGIIDVNG
                     EKIPALRGNRLSDGAPLTVYPGEVPARLPGQAFWDKQGFQFEAFRPQVMDVDKPLPHI
                     RLDAALEFLIGDKLR"
     gene            11696..12694
                     /locus_tag="RHX21_000965"
     CDS             11696..12694
                     /locus_tag="RHX21_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDV1986189.1"
                     /translation="MSPTIYDIARVAGVSKSTVSRVLNKQTNISPEAREKVLRAIEEL
                     QYQPNKLARALTSSGFDAIMVISTRSTKTTAGNPFFSEVLHAITAKAEEEGFDVILQT
                     SHNPAEDLQKCESKIKQKMIKGIIMLSSPADESFFAQLDKYDIPVVVIGKVEGQYAHV
                     YSVDTDNFGDSIALTDALIESGHQNIACLHAPLDVHVSVDRVNGYKQSLAAHNIAVRD
                     EWIVDGGYTHETALQAARELLSQSPLPEAVFATDSLKLMSIYRAAAEKNIAIPQQLAV
                     VGYSNETLSFILTPAPGGIDIPTQELGQQSCELLFRLISGKPSPQNITVATHMTLK"
     gene            complement(12805..13710)
                     /gene="ompG"
                     /locus_tag="RHX21_000966"
     CDS             complement(12805..13710)
                     /gene="ompG"
                     /locus_tag="RHX21_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monomeric porin OmpG"
                     /protein_id="HDV1986190.1"
                     /translation="MKKLLPCTALVMCAGMACAQAEERNDWHFNIGAMYEIENVEGYG
                     EDMDGLAEPSVYFNAANGPWRIALAYYQEGPVDYSAGKRGTWFDRPELEVHYQFLEND
                     DFSFGLTGGFRNYGYHYVDEPGKDTANMQRWKIAPDWDVKLTDDLRFNGWLSMYKFAN
                     DLNTTGYADTRVETETGLQYTFNETVALRVNYYLERGFNMDDSRNNGEFSTQEIRAYL
                     PLTLGNHSVTPYTRIGLDRWSNWDWQDDIEREGHDFNRVGLFYGYDFQNGLSVSLEYA
                     FEWQDHDEGDSDKFHYAGVGVNYSF"
     gene            complement(13755..14837)
                     /locus_tag="RHX21_000967"
     CDS             complement(13755..14837)
                     /locus_tag="RHX21_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDV1986191.1"
                     /translation="MAQLSLQHIQKIYDNQVHVVKDFNLEIADKEFIVFVGPSGCGKS
                     TTLRMIAGLEEISGGDLLIDGKRMNDVPAKARNIAMVFQNYALYPHMTVYDNMAFGLK
                     MQKIAKEVIDERVNWAAQILGLREYLKRKPGALSGGQRQRVALGRAIVREAGVFLMDE
                     PLSNLDAKLRVQMRAEISKLHQKLNTTMIYVTHDQTEAMTMATRIVIMKDGIVQQVGA
                     PKTVYNQPANMFVAGFIGSPAMNFIRGTIDGDKFVTETLKLTIPEEKLAVLKTQGSLH
                     KPIVMGIRPEDIHPDAQEENNISAKISVAELTGAEFMLYTTVGGHELVVRAGALNDYH
                     AGENITIHFDMTKCHFFDAETEIAIR"
     gene            complement(14851..15510)
                     /gene="pgmB"
                     /locus_tag="RHX21_000968"
     CDS             complement(14851..15510)
                     /gene="pgmB"
                     /locus_tag="RHX21_000968"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDV1986192.1"
                     /translation="MKLQGVIFDLDGVITDTAHLHFQAWQQIAAEIGISIDAQFNESL
                     KGISRDESLRRILQHGGKEGDFNSQERAQLAYRKNLLYVHSLRELTVSAVLPGIRSLL
                     ADLRAQQIPVGLASVSLNAPTILAALELREFFTFCADASQLKNSKPDPEIFLAACAGL
                     GVPPQACIGIEDAQAGIDAINASGMRSVGIGAGLTGAQLLLPSTDSLTWSRLSAFWQN
                     V"
     gene            complement(15507..17774)
                     /gene="ycjT"
                     /locus_tag="RHX21_000969"
     CDS             complement(15507..17774)
                     /gene="ycjT"
                     /locus_tag="RHX21_000969"
                     /EC_number="2.4.1.230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kojibiose phosphorylase"
                     /protein_id="HDV1986193.1"
                     /translation="MTRPVTLSEPHFSQHTLNKYASLMAQGNGYLGLRASHEEDYTRQ
                     TRGMYLAGLYHRAGKGEINELVNLPDILGMEIAINGEVFSLSREAWQRELDFASGELR
                     RSVVWRTSNGTGYTIASRRFVSADQLPLIVLEITITPLDADASVLISTGIDATQTNHG
                     RQHLDETQVRVFGQHLMQGIYTTQDGRSDVAISCCCMVSGDVQQCYTAKERRLQQHTS
                     AQLHAGETVTLQKLVWIDWRDDRQAVLDEWGSASLRQLEMCAQQSYDQLLAVSTENWR
                     QWWQKRRITVNGGEAHDQQALDYALYHLRIMTPAHDERSSIAAKGLTGEGYKGHVFWD
                     TEVFLLPFHLFSDPTVARSLLRYRWHNLPGAQEKARRNGWQGALFPWESARSGEEETP
                     EFAAINIRTGLRQKVASAQAEHHLVADIAWAVIQYWQTTGDESFIAHEGMALLLETAK
                     FWISRAVRVNDRLEIHDVIGPDEYTEHVNNNAFTSYMAYYNVQQALSIARQFGCSDDA
                     FIHRAEMFLKELRLPEIQPDGVLPQDDSFMAKPAINLAKYKAAAGKQTILLDYSRAEV
                     NEMQILKQADVVMLNYMLPEQFSAASCLANLQFYEPRTIHDSSLSKAIHGIVAARCGL
                     LTQSYQFWREGTEIDLGADPHSCDDGIHAAATGAIWLGAIQGFAGVSVRDGELHLNPA
                     LPEQWQQLSFPLFWQGCELQVTLDAQRIAIRTSAPVSLRLNGQLISVAEESVFCLGDF
                     ILPFNGTATTHQEDE"
     gene            complement(17771..18826)
                     /locus_tag="RHX21_000970"
     CDS             complement(17771..18826)
                     /locus_tag="RHX21_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDV1986194.1"
                     /translation="MKSAMTSSPLRVAIIGAGQVADKVHASYYCTRNDLELVAVCDSR
                     LSQAQALADKYGNASVWDDPQAMLLAVKPDVVSVCSPNRFHYEHTLMALEAGCHVMCE
                     KPPAMTPEQAREMCDTARKQGKVLAYDFHHRFALDTQQLREQVTNGVLGEIYVTTARA
                     LRRCGVPGWGVFTNKELQGGGPLIDIGIHMLDAAMYVLGFPAVKSVNAHSFQKIGTQK
                     SCGQFGEWDPATYSVEDSLFGTIEFHNGGILWLETSFALNIREQSIMNVSFCGDKAGA
                     TLFPAHIYTDNNGELMTLMQRELADDNRHLRSMEAFINHVQGKPVMIADAEQGYIIQQ
                     LVAALYQSAETGTRVEL"
     gene            complement(18836..19624)
                     /locus_tag="RHX21_000971"
     CDS             complement(18836..19624)
                     /locus_tag="RHX21_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415830.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDV1986195.1"
                     /translation="MKIGTQNQAFFPENILEKFRYIKEMGFDGFEIDGKLLVNNLEEV
                     KAAIKETGLPVTTTCGGYDGWIGDFIEERRLNGLKQIERILEALAEVGGKGIVVPAAW
                     GMFTFRLPPMTSPRSLDGDRKMVSDSLRVLEQVAARTGTVVYLEPLNRYQDHMINTLA
                     DARRYIVENNLKHVQIIGDFYHMNIEEDNLAQALHDNRDLLGHVHIADNHRYQPGSGT
                     LDFHALFEQLRADNYQGYVVYEGRIRAEDPAQAYRDSLAWLRTC"
     gene            complement(19643..20695)
                     /locus_tag="RHX21_000972"
     CDS             complement(19643..20695)
                     /locus_tag="RHX21_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HDV1986196.1"
                     /translation="MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVD
                     FRAASPFIDEDFNGEWQMFTPRPADAPRGIEFGKFQLGNMVVGDIIECGSDVTDYAVG
                     DSVCGYGPLSETVIINAVNNYKLRKMPQGSSWKNAVCYDPAQFAMSGVRDANVRVGDF
                     VVVVGLGAIGQIAIQLAKRAGASVVIGVDPIAHRCDIARRHGADFCLNPIGTDVGKEI
                     KTLTGKQGADVIIETSGYADALQSALRGLAYGGTISYVAFAKPFAEGFNLGREAHFNN
                     AKIVFSRACSEPNPDYPRWSRKRIEETCWELLMNGYLNCEDLIDPVVTFANSPESYMQ
                     YVDQHPEQSIKMGVTF"
     gene            complement(20726..21568)
                     /locus_tag="RHX21_000973"
     CDS             complement(20726..21568)
                     /locus_tag="RHX21_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDV1986197.1"
                     /translation="MATNKRTLSRIGFYCGLALFLIITLFPFFVMLMTSFKGAKEAIS
                     LHPTLLPQQWTLEHYVDIFNPMIFPFVDYFRNSLVVSVVSSVVAVFLGILGAYALSRL
                     RFKGRMTINASFYTVYMFSGILLVVPLFKIITALGIYDTEMALIITMVTQTLPTAVFM
                     LKSYFDTIPDEIEEAAMMDGLNRLQIIFRITVPLAMSGLISVFVYCFMVAWNDYLFAS
                     IFLSSASNFTLPVGLNALFSTPDYIWGRMMAASLVTALPVVIMYALSERFIKSGLTAG
                     GVKG"
     gene            complement(21555..22436)
                     /locus_tag="RHX21_000974"
     CDS             complement(21555..22436)
                     /locus_tag="RHX21_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDV1986198.1"
                     /translation="MNRLFSGRSDMPFALLLLAPSLLLLGGLVAWPMVSNIEISFLRL
                     PLNPNIESTFVGVSNYVRILSDPGFWHSLWMTVWYTALVVAGSTVLGLAVAMFFNREF
                     RLRKTARSLVILSYVTPSISLVFAWKYMFNNGYGIVNYLGVDLLHLYEQAPLWFDNPG
                     SSFVLVVLFAIWRYFPYAFISFLAILQTIDKSLYEAAEMDGANAWQRFRIVTLPAIMP
                     VLATVVTLRTIWMFYMFADVYLLTTKVDILGVYLYKTAFAFNDLGKAAAISVVLFIII
                     FAVILLTRKRVNLNGNK"
     gene            complement(22457..23749)
                     /locus_tag="RHX21_000975"
     CDS             complement(22457..23749)
                     /locus_tag="RHX21_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDV1986199.1"
                     /translation="MIKSKIVLLSALVSCALISGCKEENKTNVSIEFMHSSVEQERQA
                     VISKLIARFEKENPGITVKQVPVEEDAYNTKVITLSRSGSLPEVIETSHDYAKVMDKE
                     QLIDRKAVATVISNVGEGAFYDGVLRIVRTEDGSAWTGVPVSAWIGGIWYRKDVLAKA
                     GLEEPKNWQQLLDVAQKLNDPANKKYGIALPTAESVLTEQSFSQFALSNQANVFNAEG
                     KITLDTPEMMQALTYYRDLAANTMPGSNDIMEVKDAFMNGTAPMAIYSTYILPAVIKE
                     GDPKNVGFVVPTEKNSAVYGMLTSLTITAGQKTEETEAAEKFVTFMEQADNIADWVMM
                     SPGAALPVNKAVVTTATWKDNDVIKALGELPNQLIGELPNIQVFGAVGDKNFTRMGDV
                     TGSGVVSSMVHNVTVGKADLPGTLQASQKKLDELIEQH"
     gene            complement(23763..25442)
                     /gene="ycjM"
                     /locus_tag="RHX21_000976"
     CDS             complement(23763..25442)
                     /gene="ycjM"
                     /locus_tag="RHX21_000976"
                     /EC_number="2.4.1.352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415825.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosylglycerate phosphorylase"
                     /protein_id="HDV1986200.1"
                     /translation="MKQKITDYLDEIYGGTFTATHLQKLVTRLESAKRLITQRRKKHW
                     DESDVVLITYADQFHSNDLKPLPTFNQFYHQWLQSIFSHVHLLPFYPWSSDDGFSVID
                     YQQVASEAGEWQDIQQLGECSHLMFDFVCNHMSAKSEWFKNYLQQHPGFEDFFIAVDP
                     QTDLSAVTRPRALPLLTPFQMRDHSTRHLWTTFSDDQIDLNYRSPEVLLAMVDVLLCY
                     LAKGAEYVRLDAVGFMWKEPGTSCIHLEKTHLIIKLLRSIIDNVAPGTVIITETNVPH
                     KDNIAYFGAGDDEAHMVYQFSLPPLVLHAVQKQNVEALCAWAQNLTLPSSNTTWFNFL
                     ASHDGIGLNPLRGLLPESEILELVEALQQEGALVNWKNNPDGTRSPYEINVTYMDALS
                     RRESSDEERCARFILAHAILLSFPGVPAIYIQSILGSRNDYAGVEKLGYNRAINRKKY
                     HSKEITRELNDEATLRHAVYHELSRLITLRRSHNEFHPDNNFTIDTINSSVMRIQRSN
                     ADGNCLTGLFNVSKNIQHVNITNLHGRDLISEVDILGNEITLRPWQVMWIK"
     gene            complement(25654..25968)
                     /gene="pspE"
                     /locus_tag="RHX21_000977"
     CDS             complement(25654..25968)
                     /gene="pspE"
                     /locus_tag="RHX21_000977"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase PspE"
                     /protein_id="HDV1986201.1"
                     /translation="MFKKGLLALALVFSLPVFAAEHWIDVRVPEQYQQEHVQGAINIP
                     LKEVKERIATAVPDKNDTVKVYCNAGRQSGQAKEILSEMGYTHVENAGGLKDIAMPKV
                     KG"
     gene            complement(26043..26264)
                     /gene="pspD"
                     /locus_tag="RHX21_000978"
     CDS             complement(26043..26264)
                     /gene="pspD"
                     /locus_tag="RHX21_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein PspD"
                     /protein_id="HDV1986202.1"
                     /translation="MNTRWQQAGQKVKPGFKLAGKLVLLTALRYGPAGVAGWAIKSVA
                     RRPLKMLLAVALEPLLSRAANKLAQRYKR"
     gene            complement(26273..26632)
                     /gene="pspC"
                     /locus_tag="RHX21_000979"
     CDS             complement(26273..26632)
                     /gene="pspC"
                     /locus_tag="RHX21_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response membrane protein PspC"
                     /protein_id="HDV1986203.1"
                     /translation="MAGINLNKKLWRIPQQGMVRGVCAGIANYFDVPVKLVRILVVLS
                     IFFGLALFTLVAYIILSFALDPMPDNMAFGEQLPSSSELLDEVDRELAASETRLREME
                     RYVTSDTFTLRSRFRQL"
     gene            complement(26632..26856)
                     /gene="pspB"
                     /locus_tag="RHX21_000980"
     CDS             complement(26632..26856)
                     /gene="pspB"
                     /locus_tag="RHX21_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response membrane protein PspB"
                     /protein_id="HDV1986204.1"
                     /translation="MSALFLAIPLTIFVLFVLPIWLWLHYSNRSGRSELSQSEQQRLA
                     QLADEAKRMRERIQALESILDAEHPNWRDR"
     gene            complement(26910..27578)
                     /gene="pspA"
                     /locus_tag="RHX21_000981"
     CDS             complement(26910..27578)
                     /gene="pspA"
                     /locus_tag="RHX21_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein PspA"
                     /protein_id="HDV1986205.1"
                     /translation="MGIFSRFADIVNANINALLEKAEDPQKLVRLMIQEMEDTLVEVR
                     STSARALAEKKQLTRRIEQASAREVEWQEKAELALLKEREDLARAALIEKQKLTDLIK
                     SLEHEVTLVDDTLARMKKEIGELENKLSETRARQQALMLRHQAANSSRDVRRQLDSGK
                     LDEAMARFESFERRIDQMEAEAESHSFGKQKSLDDQFAELKADDAISEQLAQLKAKMK
                     QDNQ"
     gene            27745..28722
                     /gene="pspF"
                     /locus_tag="RHX21_000982"
     CDS             27745..28722
                     /gene="pspF"
                     /locus_tag="RHX21_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309907.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein operon transcriptional
                     activator"
                     /protein_id="HDV1986206.1"
                     /translation="MAEYKDNLLGEANSFLEVLEQVSHLAPLDKPVLIIGERGTGKEL
                     IASRLHYLSSRWQGPFISLNCAALNENLLDSELFGHEAGAFTGAQKRHPGRFERADGG
                     TLFLDELATAPMMVQEKLLRVIEYGELERVGGSQPLQVNVRLVCATNADLPAMVNEGT
                     FRADLLDRLAFDVVQLPPLRERESDIMLMAEHFAIQMCREIKLPLFPGFTERAKETLL
                     NYRWPGNIRELKNVVERSVYRHGTSDYPLDDIIIDPFKRRPPEDTIAVSETTSLPTLP
                     LDLREFQMQQEKELLQLSLQQGKYNQKRAAELLGLTYHQFRALLKKHQI"
     gene            complement(28842..30107)
                     /gene="puuE"
                     /locus_tag="RHX21_000983"
     CDS             complement(28842..30107)
                     /gene="puuE"
                     /locus_tag="RHX21_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-aminobutyrate transaminase"
                     /protein_id="HDV1986207.1"
                     /translation="MSNNEFHQRRLSATPRGVGVMCNFFAQSAENATLKDVEGNEYID
                     FAAGIAVLNTGHRHPDLVAAVEQQLQQFTHTAYQIVPYESYVTLAEKINALAPVSGQA
                     KTAFFTTGAEAVENAVKIARAHTGRPGVIAFSGGFHGRTYMTMALTGKVAPYKIGFGP
                     FPGSVYHVPYPSDLHGISTQDSLDAIERLFKSDIEAKQVAAIIFEPVQGEGGFNVAPK
                     ELVAAIRRLCDEHGIVMIADEVQSGFARTGKLFAMDHYADKPDLMTMAKSLAGGMPLS
                     GVVGNANIMDAPAPGGLGGTYAGNPLAVAAAHAVLNIIDKESLCERANQLGQRLKNTL
                     IDAKESVPAIAAVRGLGSMIAAEFNDPQTGEPSAAIAQKIQQRALAQGLLLLTCGAYG
                     NVIRFLYPLTIPDAQFDAAMKILQDALSD"
     gene            complement(30145..31425)
                     /gene="puuB"
                     /locus_tag="RHX21_000984"
     CDS             complement(30145..31425)
                     /gene="puuB"
                     /locus_tag="RHX21_000984"
                     /EC_number="1.4.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylputrescine oxidase"
                     /protein_id="HDV1986208.1"
                     /translation="MTEHTSSYYAASANKYAPFDTLNESISCDVCVVGGGYTGLSSAL
                     HLAEAGFDVVVLEASRIGFGASGRNGGQLVNSYSRDIDVIEKSYGMDTARMLGSMMFE
                     GGEIIRERIKRYQIDCDYRPGGLFVAMNDKQLATLEEQKENWERYGNKQLELLDANAI
                     RREVASDRYTGALLDHSGGHIHPLNLAIGEADAIRLNGGRVYELSAVTQIQHTTPAVV
                     RTAKGQVTAKYVIVAGNAYLGDKVEPELAKRSMPCGTQVITTERLSEDLARSLIPKNY
                     CVEDCNYLLDYYRLTADNRLLYGGGVVYGARDPDDVERLVVPKLLKTFPQLKGVKIDY
                     RWTGNFLLTLSRMPQFGRLDTNIYYMQGYSGHGVTCTHLAGRLIAELLRGDAERFDAF
                     ANLPHYPFPGGRTLRVPFTAMGAAYYSLRDRLGV"
     gene            complement(31427..32914)
                     /gene="puuC"
                     /locus_tag="RHX21_000985"
     CDS             complement(31427..32914)
                     /gene="puuC"
                     /locus_tag="RHX21_000985"
                     /EC_number="1.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase PuuC"
                     /protein_id="HDV1986209.1"
                     /translation="MNFHHLAYWQDKALSLAIENRLFINGEYTAAAENETFETVDPVT
                     QAPLAKIARGKSVDIDRAVSAARGVFERGDWSLSSPAKRKAVLNKLADLMEAHAEELA
                     LLETLDTGKPIRHSLRDDIPGAARAIRWYAEAIDKVYGEVATTSSHELAMIVREPVGV
                     IAAIVPWNFPLLLTCWKLGPALAAGNSVILKPSEKSPLSAIRLAGLAKEAGLPDGVLN
                     VVTGFGHEAGQALSRHNDIDAIAFTGSTRTGKQLLKDAGDSNMKRVWLEAGGKSANLV
                     FADCPDLQKAASATAAGIFYNQGQVCIAGTRLLLEESIADEFLALLKQQAQNWQPGHP
                     LDPATTMGTLIDCAHADSVHSFIREGESKGQLLLDGRNAELAAAIGPTIFVDVDPNAS
                     LSREEIFGPVLVVTRFTSEDQALQLANDSQYGLGAAVWTRDLSRAHRMSRRLKAGSVF
                     VNNYNDGDMTVPFGGYKQSGNGRDKSLHALEKFTELKTIWISLEA"
     gene            complement(33189..33746)
                     /gene="puuR"
                     /locus_tag="RHX21_000986"
     CDS             complement(33189..33746)
                     /gene="puuR"
                     /locus_tag="RHX21_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator PuuR"
                     /protein_id="HDV1986210.1"
                     /translation="MSDEGLAPGKRLSEIRQQQGLSQRRAAELSGLTHSAISTIEQDK
                     VSPAISTLQKLLKVYGLSLSEFFSEPEKPDEPQVVINQDDLIEMGSQGVSMKLVHNGN
                     PNRTLAMIFETYQPGTTTGERIKHQGEEIGTVLEGEIVLTINGQDYHLVAGQSYAINT
                     GIPHSFSNTSAGICRIISAHTPTTF"
     gene            complement(33773..34537)
                     /gene="puuD"
                     /locus_tag="RHX21_000987"
     CDS             complement(33773..34537)
                     /gene="puuD"
                     /locus_tag="RHX21_000987"
                     /EC_number="3.5.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415814.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase"
                     /protein_id="HDV1986211.1"
                     /translation="MENIMNNPVIGVVMCRNRLKGHATQTLQEKYLNAIIHAGGLPIA
                     LPHALAEPSLLEQLLPKLDGIYLPGSPSNVQPHLYGENGDEPDADPGRDLLSMALINA
                     ALERRIPIFAICRGLQELVVATGGSLHRKLCEQPELLEHREDPELPVEQQYAPSHEVQ
                     VEEGGLLSALLPECSNFWVNSLHGQGAKVVSPRLRVEARSPDGLVEAVSVINHPFALG
                     VQWHPEWNSSEYALSRILFEGFITACQHHIAEKQRL"
     gene            34749..36167
                     /gene="puuA"
                     /locus_tag="RHX21_000988"
     CDS             34749..36167
                     /gene="puuA"
                     /locus_tag="RHX21_000988"
                     /EC_number="6.3.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415813.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-putrescine ligase"
                     /protein_id="HDV1986212.1"
                     /translation="METNIVEVENFVQQSEERRGSAFTQEVKRYLERYPNTQYVDVLL
                     TDLNGCFRGKRIPVSSLKKLEKGCYFPASVFAMDILGNVVEEAGLGQEMGEPDRTCVP
                     VLGSLTPSAADPEFIGQMLLTMVDEDGAPFDVEPRNVLNRLWQQLRQRGLFPVVAVEL
                     EFYLLDRQRDAEGYLQPPCAPGTDDRNTQSQVYSVDNLNHFADVLNDIDELAQLQLIP
                     ADGAVAEASPGQFEINLYHTDNVLEACDDALALKRLVRLMAEKHKMHATFMAKPYEEH
                     AGSGMHIHISMQNNRGENVLSDAEGEDSPLLKKMLAGMIDLMPSSMALLAPNVNSYRR
                     FQPGMYVPTQASWGHNNRTVALRIPCGDRHNHRVEYRVAGADANPYLVMAAIFAGILH
                     GLDNELPLQEEVEGNGLEQEGLPFPIRQSDALGEFIENDHLRRYLGERFCHVYHACKN
                     DELLQFERLITETEIEWMLKNA"
     gene            36316..36480
                     /locus_tag="RHX21_000989"
     CDS             36316..36480
                     /locus_tag="RHX21_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986213.1"
                     /translation="MPMIKSPHGEGGCVCAPPATDWTPPPLLPLLNRFDFRSTRPQTL
                     LRRGGSNYGY"
     gene            36470..37855
                     /gene="puuP"
                     /locus_tag="RHX21_000990"
     CDS             36470..37855
                     /gene="puuP"
                     /locus_tag="RHX21_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309900.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine/proton symporter PuuP"
                     /protein_id="HDV1986214.1"
                     /translation="MAINSPLNIAAQPGKTRLRKSLKLWQVVMMGLAYLTPMTVFDTF
                     GIVSGISDGHVPASYLLALAGVLFTAISYGKLVRQFPEAGSAYTYAQKSINPHVGFMV
                     GWSSLLDYLFLPMINVLLAKIYLSALFPEVPPWVWVVTFVAILTAANLKSVNLVANFN
                     TLFVLVQISIMVVFIFLVVQGLHKGEGVGTVWSLQPFISENAHLIPIITGATIVCFSF
                     LGFDAVTTLSEETPDAARVIPKAIFLTAVYGGVIFIAASFFMQLFFPDISRFKDPDAA
                     LPEIALYVGGKLFQSIFLCTTFVNTLASGLASHASVSRLLYVMGRDNVFPERVFGYVH
                     PKWRTPALNVIMVGIVAMSALFFDLVTATALINFGALVAFTFVNLSVFNHFWRRKGMN
                     KSWKEHFHYLLMPLVGALTVGVLWINLEATSLTLGLVWASLGGAYLWYLIRRYRKVPL
                     YEGDRTPVSET"
     gene            37989..38234
                     /locus_tag="RHX21_000991"
     CDS             37989..38234
                     /locus_tag="RHX21_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmjA family protein"
                     /protein_id="HDV1986215.1"
                     /translation="MNHDIPLKYFDIADEYATECAEPVADAERTPLAHYFQLLLTRLM
                     NNEEISEEAQHEMAAEAGINPVRIDEIAEFLNQWGNE"
     gene            38547..40190
                     /gene="sapA"
                     /locus_tag="RHX21_000992"
     CDS             38547..40190
                     /gene="sapA"
                     /locus_tag="RHX21_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein SapA"
                     /protein_id="HDV1986216.1"
                     /translation="MRQVLSSLLVIAGLVSGQAIAAPESPPHADIRDSGFVYCVSGQV
                     NTFNPSKASSGLIVDTLAAQFYDRLLDVDPYTYRLMPELAESWEVLDNGATYRFHLRR
                     DVPFQKTDWFTPTRKMNADDVVFTFQRIFDRNNPWHNVNGSNFPYFDSLQFADNVKSV
                     RKLDNHTVEFRLAQPDASFLWHLATHYASVMSAEYARKLEKEDRQEQLDRQPVGTGPY
                     QLSEYRAGQFIRLQRHDDFWRGKPLMPQVVVDLGSGGTGRLSKLLTGECDVLAWPAAS
                     QLSILRDDPRLRLTLRPGMNVAYLAFNTAKPPLNNPAVRHALALAINNQRLMQSIYYG
                     TAETAASILPRASWAYDNEAKITEYNPAKSREQLKALGLENLTLKLWVPTRSQAWNPS
                     PLKTAELIQADMAQVGVKVVIVPVEGRFQEARLMDMSHDLTLSGWATDSNDPDSFFRP
                     LLSCAAIHSQTNLAHWCDPKFDSVLRKALSSQQLAARIEAYDEAQSILAQELPILPLA
                     SSLRLQAYRYDIKGLVLSPFGNASFAGVYREKQDEVKKP"
     gene            40187..41152
                     /gene="sapB"
                     /locus_tag="RHX21_000993"
     CDS             40187..41152
                     /gene="sapB"
                     /locus_tag="RHX21_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease SapB"
                     /protein_id="HDV1986217.1"
                     /translation="MIIFTLRRILLLIVTLFLLTFVGFSLSYFTPHAPLQGASLWNAW
                     VFWFNGLIHWDFGVSSINGQPIAEQLKEVFPATMELCILAFGFALIVGIPVGMIAGIT
                     RHKWQDNLINAIALLGFSIPVFWLALLLTLFCSLTLGWLPVSGRFDLLYEVKPITGFA
                     LIDAWLSDSPWRDEMIMSAIRHMILPVITLSVAPTTEVIRLMRISTIEVYDQNYVKAA
                     ATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAI
                     RQQDYAAISAGVMVCGSLVIIVNVISDILGAMANPLKHKEWYALR"
     gene            41139..42029
                     /gene="sapC"
                     /locus_tag="RHX21_000994"
     CDS             41139..42029
                     /gene="sapC"
                     /locus_tag="RHX21_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease SapC"
                     /protein_id="HDV1986218.1"
                     /translation="MPYDSVYSEKRPPGTLRTAWRKFYSDASAMVGLYGCAGLAVLCI
                     FGGWFAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGTDDLGRDVLSRLLSGAAPTVGGA
                     FVVTLAATICGLVLGTFAGATHGLRSAVLNHILDTLLAIPSLLLAIIVVAFAGPSLSH
                     AMFAVWLALLPRMVRSIYSMVHDELEKEYVIAARLDGASTLNILWFAVMPNITAGLVT
                     EITRALSMAILDIAALGFLDLGAQLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMIS
                     VLLVNLLGDGVRRAIIAGVE"
     gene            42029..43021
                     /gene="sapD"
                     /locus_tag="RHX21_000995"
     CDS             42029..43021
                     /gene="sapD"
                     /locus_tag="RHX21_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein
                     SapD"
                     /protein_id="HDV1986219.1"
                     /translation="MPLLDIRNLTIEFKTGDEWVKAVDRVSMTLTEGEIRGLVGESGS
                     GKSLIAKAICGVNKDNWRVTADRMRFDDIDLLRLSARERRKLVGHNVSMIFQEPQSCL
                     DPSERVGRQLMQNIPAWTYKGRWWQRFGWRKRRAIELLHRVGIKDHKDAMRSFPYELT
                     EGECQKVMIAIALANQPRLLIADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHD
                     LQMLSQWADKINVLYCGQTVETAPSKELVTMPHHPYTQALIRAIPDFGSAMPHKSRLN
                     TLPGAIPLLEQLPIGCRLGPRCPYAQRECIVTPRLTGAKNHLYACHFPLNMEKE"
     gene            43023..43829
                     /gene="sapF"
                     /locus_tag="RHX21_000996"
     CDS             43023..43829
                     /gene="sapF"
                     /locus_tag="RHX21_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein
                     SapF"
                     /protein_id="HDV1986220.1"
                     /translation="MIETLLEVRNLSKTFRYRTGWFRRQTVEAVKPLSFTLREGQTLA
                     IIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYSFRSQRIRMIFQDPSTSLN
                     PRQRISQILDFPLRLNTDLEPEQRRKQIIETMRMVGLLPDHVSYYPHMLAPGQKQRLG
                     LARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHIGMMKHIS
                     DQVLVMHQGEVVERGSTADVLASPLHELTKRLIAGHFGEALTADAWRKDR"
     gene            43897..44250
                     /locus_tag="RHX21_000997"
     CDS             43897..44250
                     /locus_tag="RHX21_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF559 domain-containing protein"
                     /protein_id="HDV1986221.1"
                     /translation="MMDKIKSNARDLRSNLTLQERKLWRYLRSRRFGDFKFRRQHPVG
                     SYILDFACCSARVVVELDGGQHDLAVAYDSRRTSWLESQGWTVLRFWNNEIDCNEETV
                     LENILQELNRRSPSP"
     gene            44620..45408
                     /gene="fabI"
                     /locus_tag="RHX21_000998"
     CDS             44620..45408
                     /gene="fabI"
                     /locus_tag="RHX21_000998"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HDV1986222.1"
                     /translation="MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKL
                     KGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDG
                     DYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMG
                     LAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRR
                     TVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNELELK"
     gene            45553..46680
                     /locus_tag="RHX21_000999"
     CDS             45553..46680
                     /locus_tag="RHX21_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309887.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CMD domain-containing protein"
                     /protein_id="HDV1986223.1"
                     /translation="MEQRHITGKSHWYHETQSSTAEYDVLPLVPEAAKVSDPFLLDVI
                     LDEETLAPFLSWLVPARVLAVELFPDQLTVTRSQTFTAYERLSTALTVAQVCGVQRLC
                     NYYSARLTPLPGPDSSRESNHRLAQITQYARQLASSPSIIDNRSRQHLNDVGLTAGDC
                     VIINQIIGFIGFQARTIATFQAYLGHPVRWLPGLEIQNYADASLFADESIRWRSSYEV
                     EKLPEEYTKSSTAELCQLAETLSLHPISLSLLERLLNSTRVNTQPDNKLAALLCARIN
                     GSPACFAACMDSSNEYKKISPLLRKGENEINQWADRHSVEHATVQAIQWLTRAPDRFS
                     AAQFSPLLEHEKSSTQIINLLVWSGLCGWINRLKIALGETY"
     gene            46748..48682
                     /gene="rnb"
                     /locus_tag="RHX21_001000"
     CDS             46748..48682
                     /gene="rnb"
                     /locus_tag="RHX21_001000"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exoribonuclease II"
                     /protein_id="HDV1986224.1"
                     /translation="MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSY
                     FIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVEPFLTRFVGKVQGKNDRLAIVPD
                     HPLLKDAIPCRAARGLNHEFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVP
                     WWVTLARHNLEKEAPDGVATEMLDEGLVREDLTALDFVTIDSASTEDMDDALFAKALP
                     DDKLQLIVAIADPTAWIAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRAN
                     EVRPVLACRMTLSADGTIEDNIEFFAATIESKAKLVYDQVSDWLENTGDWQPESEAIA
                     EQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEA
                     MIAANICAARVLRDKLGFGIYNVHMGFDPANADALAALLKTHGLHVDAEEVLTLDGFC
                     KLRRELDAQPTGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINH
                     RLLKAVIKGETATRPQDEITVQMAERRRLNRMAERDVGDWLYARFLKDKAGTDTRFAA
                     EIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETVYKVTDVI
                     DVTIAEVRMETRSIIARPVA"
     gene            complement(48760..48864)
                     /locus_tag="RHX21_001001"
     CDS             complement(48760..48864)
                     /locus_tag="RHX21_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986225.1"
                     /translation="MTYMKLTAAKRIVFFIYLFVIQFWKNASFQTKVS"
     gene            48918..50903
                     /gene="pdeR"
                     /locus_tag="RHX21_001002"
     CDS             48918..50903
                     /gene="pdeR"
                     /locus_tag="RHX21_001002"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-GMP phosphodiesterase"
                     /protein_id="HDV1986226.1"
                     /translation="MKTVRESTTLYNFLGSHNPYWRLTESSDVLRFSTTETTEPDRTL
                     QLSAEQAARIREMTVITSSLMMSLTVDESDLSVHLVGRKINKREWAGNASAWHDTPAV
                     ARDLSHGLSFAEQVVSEAHSAIVILDSRGNIQRFNRLCEDYTGLKEHDVIGQSVFKLF
                     MSRREAAASRRNNRVFFRSGNAYEVELWIPTCKGQRLFLFRNKFVHSGSGKNEIFLIC
                     SGTDITEERRAQERLRILANTDSITGLPNRNAMQDLIDHAINHADNNKVGVVYLDLDN
                     FKKVNDAYGHLFGDQLLRDVSLAILSCLEHDQVLARPGGDEFLVLASNTSQSALEAMA
                     SRILTRLRLPFRIGLIEVYTSCSVGIALSPEHGSDSTAIIRHADTAMYTAKEGGRGQF
                     CVFTPEMNQRVFEYLWLDTNLRKALENDQLVIHYQPKITWRGEVRSLEALVRWQSPER
                     GLIPPLDFISYAEESGLIVPLGRWVILDVVRQVAKWRDKGINLRVAVNISARQLADQT
                     IFTALKQVLQELNFEYCPIDVELTESCLIENDELALSVIQQFSQLGAQVHLDDFGTGY
                     SSLSQLARFPIDAIKLDQVFVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVESAKE
                     DAFLTKNGINERQGFLFAKPMPAVAFERWYKRYLKRA"
     gene            51050..51223
                     /locus_tag="RHX21_001003"
     CDS             51050..51223
                     /locus_tag="RHX21_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986227.1"
                     /translation="MSEFDAQRVAERIDIVLDILVAGDYHSAIHNLEILKAELLRQVA
                     ESTPDIPKAPWEI"
     gene            51313..52062
                     /locus_tag="RHX21_001004"
     CDS             51313..52062
                     /locus_tag="RHX21_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDV1986228.1"
                     /translation="MNSRQQTILQMVIDQGQVSVTDLAKATGVSEVTIRQDLNTLEKL
                     SYLRRAHGFAVSLDSDDVETRMMSNYTLKRELAEFAASLVQPGETIFIENGSSNALLA
                     RTLGEQKKNVTIITVSSYIAHLLKDAPCEVILLGGVYQKKSESMVGPLTRQCIQQVHF
                     SKAFIGIDGWQPETGFTGRDMMRTDVVNAVLEKECEAIVLTDSSKFGAVHSYSIGPVE
                     RFNRVITDSKIRASDLMHLEHSKLTVHVVDI"
     gene            52331..52549
                     /gene="osmB"
                     /locus_tag="RHX21_001005"
     CDS             52331..52549
                     /gene="osmB"
                     /locus_tag="RHX21_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotically-inducible lipoprotein OsmB"
                     /protein_id="HDV1986229.1"
                     /translation="MFVTSKKMTAAVLAITLAMSLSACSNWSKRDRNTAIGAGAGALG
                     GAVLTDGSTLGTLGGAAVGGVIGHQVGK"
     gene            complement(52675..53001)
                     /gene="yciH"
                     /locus_tag="RHX21_001006"
     CDS             complement(52675..53001)
                     /gene="yciH"
                     /locus_tag="RHX21_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415798.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response translation initiation inhibitor
                     YciH"
                     /protein_id="HDV1986230.1"
                     /translation="MSDSNSRLVYSTETGRIDEPKAAPVRPKGDGVVRIQRQTSGRKG
                     KGVCLITGVDLDDAELTKLAAELKKKCGCGGAVKDGVIEIQGDKRDLLKSLLEAKGMK
                     VKLAGG"
     gene            complement(53001..53738)
                     /gene="pyrF"
                     /locus_tag="RHX21_001007"
     CDS             complement(53001..53738)
                     /gene="pyrF"
                     /locus_tag="RHX21_001007"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HDV1986231.1"
                     /translation="MTLTASSSSRAVTNSPVVVALDYHNRDDALSFVDKIEPRDCRLK
                     VGKEMFTLFGPQFVRELQQRGFDIFLDLKFHDIPNTAAHAVAAAADLGVWMVNVHASG
                     GARMMTAAREALVPFGKDAPLLIAVTVLTSMEASDLVDLGMTLSPADYAERLAALTQK
                     CGLDGVVCSAQEAVRFKQVFGQEFKLVTPGIRPQGSEAGDQRRIMTPEQALSAGVDYM
                     VIGRPVTQSVDPAQTLKAINASLQRSA"
     gene            complement(53931..55100)
                     /gene="lapB"
                     /locus_tag="RHX21_001008"
     CDS             complement(53931..55100)
                     /gene="lapB"
                     /locus_tag="RHX21_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapB"
                     /protein_id="HDV1986232.1"
                     /translation="MLELLFLLLPVAAAYGWYMGRRSAQQNKQDEANRLSRDYVAGVN
                     FLLSNQQDKAVDLFLDMLKEDTGTVEAHLTLGNLFRSRGEVDRAIRIHQTLMESASLT
                     YEQRLLAIQQLGRDYMAAGLYDRAEDMFNQLTDETDFRIGALQQLLQIYQATSEWQKA
                     IDVAERLVKLGKDKQRVEIAHFYCELALQHMASDDLDRAMTLLKKGAAADKNSARVSI
                     MMGRVFMAKGEYAKAVESLQRVISQDRELVSETLEMLQTCYQQLGKTAEWAEFLQRAV
                     EENTGADAELMLADIIEARDGSEAAQVYITRQLQRHPTMRVFHKLMDYHLNEAEEGRA
                     KESLMVLRDMVGEKVRSKPRYRCQKCGFTAYTLYWHCPSCRAWSTIKPIRGLDGL"
     gene            complement(55107..55415)
                     /gene="lapA"
                     /locus_tag="RHX21_001009"
     CDS             complement(55107..55415)
                     /gene="lapA"
                     /locus_tag="RHX21_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA"
                     /protein_id="HDV1986233.1"
                     /translation="MKYLLIFLLVLAIFVISVTLGAQNDQQVTFNYLLAQGEYRISTL
                     LAVLFAAGFAIGWLICGLFWLRVRVSLARAERKIKRLENQLSPATDVAVVPHSSAAKE
                     "
     gene            complement(55564..56328)
                     /gene="pgpB"
                     /locus_tag="RHX21_001010"
     CDS             complement(55564..56328)
                     /gene="pgpB"
                     /locus_tag="RHX21_001010"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase B"
                     /protein_id="HDV1986234.1"
                     /translation="MRSIARRTAVGAALLLVMPVAVWISGWRWQPGEQSWLLKAAFWV
                     TETVTQPWGVITHLILFGWFLWCLRFRIKAAFVLFAILAAAILVGQGVKSWIKDKVQE
                     PRPFVIWLEKTHHIPVDEFYTLKRAERGNLVKEQLAEEKNIPQYLRSHWQKETGFAFP
                     SGHTMFAASWALLAVGLLWPRRRTLTIAILLVWATGVMGSRLLLGMHWPRDLVVATLI
                     SWALVAVATWLAQRICGPLTPPAEENREIAQREQES"
     gene            56498..57088
                     /gene="ribA"
                     /locus_tag="RHX21_001011"
     CDS             56498..57088
                     /gene="ribA"
                     /locus_tag="RHX21_001011"
                     /EC_number="3.5.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase II"
                     /protein_id="HDV1986235.1"
                     /translation="MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGHT
                     PVLARVHSECLTGDALFSLRCDCGFQLEAALTQIAEEGRGILLYHRQEGRNIGLLNKI
                     RAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVNEVRLLTNNPKKVEILTE
                     AGINIVERVPLIVGRNPNNEHYLDTKAEKMGHLLNK"
     gene            complement(57152..59827)
                     /gene="acnA"
                     /locus_tag="RHX21_001012"
     CDS             complement(57152..59827)
                     /gene="acnA"
                     /locus_tag="RHX21_001012"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase AcnA"
                     /protein_id="HDV1986236.1"
                     /translation="MSSTLREASKDTLQAKDKTYHYYSLPLAAKSLGDITRLPKSLKV
                     LLENLLRWQDGNSVTEEDIHALAGWLKNAHADREIAYRPARVLMQDFTGVPAVVDLAA
                     MREAVKRLGGDTAKVNPLSPVDLVIDHSVTVDRFGDDEAFEENVRLEMERNHERYVFL
                     KWGKQAFSRFSVVPPGTGICHQVNLEYLGKAVWSELQDGEWIAYPDTLVGTDSHTTMI
                     NGLGVLGWGVGGIEAEAAMLGQPVSMLIPDVVGFKLTGKLREGITATDLVLTVTQMLR
                     KHGVVGKFVEFYGDGLDSLPLADRATIANMSPEYGATCGFFPIDAVTLDYMRLSGRSE
                     DQVELVEKYAKAQGMWRNPGDEPIFTSTLELDMNDVEASLAGPKRPQDRVALPDVPKA
                     FAASNELEVNATHKDRQPVDYVMNGHQYQLPDGAVVIAAITSCTNTSNPSVLMAAGLL
                     AKKAVTLGLKRQPWVKASLAPGSKVVSDYLAKAKLTPYLDELGFNLVGYGCTTCIGNS
                     GPLPDPIETAIKKGDLTVGAVLSGNRNFEGRIHPLVKTNWLASPPLVVAYALAGNMNI
                     NLASEPIGHDRKGDPVYLKDIWPSAQEIARAVEQVSTEMFRKEYAEVFEGTAEWKEIN
                     VTRSDTYGWQEDSTYIRLSPFFDEMQATPAPVEDIHGARILAMLGDSVTTDHISPAGS
                     IKPDSPAGRYLQGRGVERKDFNSYGSRRGNHEVMMRGTFANIRIRNEMVPGVEGGMTR
                     HLPDSDVVSIYDAAMRYKQEQTPLAVIAGKEYGSGSSRDWAAKGPRLLGIRVVIAESF
                     ERIHRSNLIGMGILPLEFPQGVTRKTLGLTGEEKIDIGDLQNLQPGATVPVTLTRADG
                     SQEVVPCRCRIDTATELTYYQNDGILHYVIRNMLK"
     gene            complement(59991..60086)
                     /locus_tag="RHX21_001013"
     CDS             complement(59991..60086)
                     /locus_tag="RHX21_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986237.1"
                     /translation="MINTNMKYWSWMGAFSLSMLFWAELLWIITH"
     gene            complement(60200..60367)
                     /locus_tag="RHX21_001014"
     CDS             complement(60200..60367)
                     /locus_tag="RHX21_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588450.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986238.1"
                     /translation="MVGQEQLESSPLCQHSDNETETKRECSVVIPDDWQLTSQQQAFI
                     ELFAEDDQPKQ"
     gene            complement(60370..60534)
                     /locus_tag="RHX21_001015"
     CDS             complement(60370..60534)
                     /locus_tag="RHX21_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmiA family putative membrane protein"
                     /protein_id="HDV1986239.1"
                     /translation="MLISDGDYMRLAMPSGNQEPRRDPELKRKAWLAVFLGSALFWVV
                     VALLIWKVWG"
BASE COUNT        14613 a        16036 c        15007 g        15083 t
ORIGIN      
        1 ttctgacgat taagctattt ttgctgatta atcagtttga aaaacagcag attaaaaaag
       61 gtcgcgatat caccagtgcg cggattatgt cgcgcattat caaaatcacc attattgtgg
      121 tgcttgttct gctttatggc gaacatttcg gcatgagcct ttctggcttg ctgacctttg
      181 gtggtattgg tggtctggct gtcggtatgg ccggtaaaga tattctgagt aatttctttt
      241 ccgggatcat gctctatttc gaccgtcctt tcagtattgg cgactggatc cgttcaccgg
      301 acagaaatat cgaaggtaca gtagcggaaa ttggctggcg aattaccaaa attacgacct
      361 ttgataatcg tccattgtac gtaccgaact cgctgttttc atcgatcagc gtagaaaacc
      421 caggacgaat gaccaaccgc cgcattacca cgaccattgg tttacgttat gaggatgcgg
      481 caaaagtggg cgttattgtc gaagccgtac gtgagatgct gaaaaatcac ccggccatcg
      541 accagcgaca aaccttactg gtttatttca accagtttgc cgactcgtca ttgaatatta
      601 tggtttattg ctttaccaaa accacggtat gggctgagtg gcttgctgca cagcaagacg
      661 tttatttgaa gattatcgat attgtacagt cacacggcgc ggactttgcc ttccccagcc
      721 agacgctgta tatggataac attacaccgc cggaacaggg tcgctaaatc agacatcact
      781 ggcgttatcc acaagggtaa cgccagttcc catcacatca atgcttcaca atatacatag
      841 tccggctgta cgccacatct tccgggttat taatgggata acctttcagc cacggcttga
      901 ttaatcgtcc attggtatat tgataaattg gtgcaatcgg tgcttgctcc atgaggattt
      961 tttctgccgc gttgtaatcg gcattacgcg ctttaacggt attttccgtc gatgcctggg
     1021 ccagaacttt gtcgtatgcc ggattgttaa agcgtgaaat atttcctgaa tgcgttgacg
     1081 ttaataatgt caggaaagtg gagggttcat tataatcccc cacccatgag gcacggataa
     1141 catcaaaatt gccggtgtta cggctatcga tataggtttt ccattcctga ttttgcaatt
     1201 taacatctac gccaaggttc tttttccaca tcgatgctac agcaatcgca attttttgat
     1261 ggttttctga agtgttatac aaaagcgtca gcttcagcgg tttttgcgga ccataaccag
     1321 ctgcgctcaa caaagttttt gcctgtgcat tcagttcttc ctgactcatt tgttcaaacg
     1381 gcgaaggttc cggcgtaaat ccggcggtaa catctggtgt aaaatgccac gctggctttt
     1441 cgcccgttcc caacactttt tcggtcatca ggcggcgatc tatcgtcata cttaatgcca
     1501 ggcgaacgcg ctgatctgcc gtcggccctt tttgcgtgtt aaacgcataa taataggtcc
     1561 cgagctgtgg cggcgtataa acctgccccg gaatatcctt caacagcttc tgatacatat
     1621 ttttcgggaa ggattcggtg atatcaatat cccccgcgag gtaacgctta gtggctgcgg
     1681 attcctgatt aattggcagg aaggtcactt tttgcagtac cgttttggcg ttatcccaat
     1741 aatgggtatt cggtaccacg accagttttt cattgactac gcgatcttta agaacataag
     1801 cgccattgcc gatcagattt ccgggtttcg tccactcttt accgctttct acgttggctt
     1861 tttgcaccgg gaagaaggca aagttagcgg ttaaattcac aaaccacggc aacggtttat
     1921 caagctgaat tttcaaggta tgggcatcaa ctgcggtgac gccaagctgg tcaggcgtag
     1981 ctttaccatc aataatcgcc tgtgcgttgt tgattcccgc cagcgcggca aaccatgcaa
     2041 atggcgatag cgttttcggg tccaccagac gctgccagct gtagacaaaa tcttgcgccg
     2101 ttaccggtgt gccatccgcc cattttgcgt tatcgcgcag ggtaaaagtc cagatacggt
     2161 tgtcattact tttccactga gtcgcaacgc cggggacaat ctcccctttc tcgttctgat
     2221 tcaccagtcc ttcaaacaga tcgcgaatga cctgaatctc tggcaggccc acggctttag
     2281 cgggatccag cgacgcaggc tcatctttaa tgtggcgcac cagctcctgc ttctctgcca
     2341 gtactgtgcc gctcggaact tctgcagcat acgaaagaga aatgctgctg accaacagcg
     2401 cacaacacgt gactgaaaca gagtgcttca taagtttccc tctaaccgac attaaaattg
     2461 atgcgtaatt atttgtttcg ccttaaagaa atgcaaacaa cttccatcaa aaaagtgaca
     2521 caggaagcat aaaatgtttt atgtatcaat atattaaatc agatttagtg taaataatcg
     2581 acgccaaaat gcggcaaagc acatagaaca ccgaacacta cgttcaggct tcgcacgttc
     2641 aaaccagttt tcggtatcaa aatcagcatc tgtcgccatt gtacgaagaa taaaaaataa
     2701 ccaaaacgtt gaaaggaact gagaatacgt taagagagaa attaaattaa tgtatcagca
     2761 agtagtgcta aacagcacct ttatacttca gcctatctat aaataatgag aatgccgagc
     2821 cagcatgtcg acggtgtgga tagtacaggt gataaccggg taaatctggt gtgaatttat
     2881 ccaaaacacg tatcagtttt ttttctttaa tagcccgctc aacctgatca taaggtagat
     2941 acgccaatcc atgcccatca attgcagcat caatgatcag gtctatcgta ttcagtaaaa
     3001 gctgaccttc catgcgaaca cgaacttcac gtccaccgcg tattaatctc cagcgatttg
     3061 ctgtacccga tgtgggaaga tacaaattaa ttgcctgatg atctattaat tgtgacactg
     3121 acgttggaac acttcggcga gaaaaataat ccggtgagcc aacaatagcc attggtatat
     3181 ctggcccgat tcgaatggcg atcatatctt tatccatctc cccacccaga cggacgcctg
     3241 catcaaaacg ttcagaaacg acatcggtca aaccataatc aatggtgagc tgaatatcaa
     3301 tttcaggatg cgatttcagg aatgtgcgca ttgctggtaa caatatcgtt tttgctgcat
     3361 gttctacagt agtaatacgt attgtcccgg atgggcggtt ctgcagctcg ctcagggatg
     3421 ccagggctga atctatgtca tgcaacatag ggccaagaac agacaaaaga tgctcgcccg
     3481 cttcagttgg aacaacgctg cgcgtggttc gcgtcagaag ccgcaatccc aatcgttctt
     3541 ctatacgacg cactatctgg cttaaagctg actgcgccat gctcaggcgg gctgctgcac
     3601 gagtgaagct acgctcctct gcaacgacga caaacgccat cagatcagcg atttcttcac
     3661 gcttcattca gtatctccat gcaatctatt aatcatttaa atgataggtc taatcatgat
     3721 tttgggtcta atcaacttaa tgatcaatat ctatagtgat atcaccaacc gttaaaacga
     3781 accgacaact ccatgaggaa cggaatgatg aataataaag tcagcttcac taacagcaat
     3841 aatccaacca tctctttgtc tgcagtgatc tatttccctc caaaatttga tgaaacccgt
     3901 cagtatcagg caattgtggt atctcaccca ggtgggggcg ttaaagaaca aacggccgga
     3961 acctatgcca aaaaactggc ggaaaaggga tttgtcacta ttgcttatga cgcatcttat
     4021 caaggtgaaa gtggcggcga gccgcgtcag ttagaaaacc catacattcg tactgaagac
     4081 atcagtgccg tgattgatta cctgacaacg ctttcttatg tcgacaatac ccgaattggt
     4141 gcgatgggaa tttgtgccgg tgcaggatat acagccaatg ctgcaattca ggatcgccgc
     4201 atcaaggcca tcggtaccgt tagtgcggtc aatattggtt cgatgttccg taatggttgg
     4261 gaaaacaatg tgaaatctat tgatgccctg ccatacgttg aagcgggttc aaacgcccga
     4321 accagcgata ttagcagcgg agaatatgcc gttatgccac tggcaccaat gaaggagtcc
     4381 gatgcgccga acgaagaact gcgtcaggcc tgggagtatt accacacccc tcgcgcgcag
     4441 tatccaacag caccgggtta cgctactttg cgcagcctta accagattat tacctatgat
     4501 gcttaccata tggcggaagt gtacctgact cagccgatgc agattgtggc gggcagccag
     4561 gcagggagca aatggatgag tgacgacctg tacgatcggg catcaagcca ggataaacgc
     4621 tatcacattg ttgaaggcgc aaaccatatg gatctttatg acggcaaagc ctatgtggct
     4681 gaagcaattt cagtattagc tccgttcttt gaggaaactc tgtaatgaaa catattcaaa
     4741 tccgcaatag tgatatggcc tggcatattg ctgccaataa tctgggataa ttttcatgaa
     4801 aaatgtactg attcttggtg ctggcggtca gatagcccgc catgtgatta atcaactggc
     4861 agataagcaa accattaaac aaactttatt tgcccgtcag ccagcaaaaa tccacaaacc
     4921 ctatccaact aataaaatgc aaacaacttc cggcaaaaaa gtgatacaag atcgatgaca
     4981 tagcgttgaa gaaaaggatt tgataatccg caaaatttgc acaacactgc ctgtaatact
     5041 tcctgaacca gagacgatca tgaccgtaac ccgcccacgc gccgaacgcg gcgcatttcc
     5101 gcccggaaca gaacattacg gacgttcatt attgggcgcg ccgttaatct ggtttcctgc
     5161 ccctgcagcc agtcgcgaaa gtggtttgat tctggctggc actcacggtg atgaaaactc
     5221 ttcggtcgtc acgctctcct gtgctctgcg gactttgaca ccttctttgc gccgccatca
     5281 tgtggtgctg tgtgtgaatc ctgacggctg ccagctgggg ttacgggcca atgctaatgg
     5341 tgtggattta aacagaaact ttccggcggc gaactggaag gaaggtgaaa cagtttatcg
     5401 ctggaacagc gccgctgaag aacgtgatgt cgtattactg acaggtgaca aacctggctc
     5461 cgaacctgaa accctggcgc tgtgccagct tatacaccgc attcaacctg cctgggtggt
     5521 ctcattccac gatccactgg cttgtattga agatcccaga cacagcgaat taggcgaatg
     5581 gctggcccag gcgtttgaat tgcctctggt aaccagcgtc ggttatgaaa cgcctggctc
     5641 tttcggcagt tggtgtgcag atctcaactt gcattgcatc accgcagagt ttccgcccat
     5701 ctcctccgac gaagccagcg aaaaatatct ctttgcgatg gcaaacttgc tgcgctggca
     5761 tcctaaagat gcaattcgcc cgtcgtgaac tgaagcgctg gttccacatc taccgccagc
     5821 caggtcggtc cgtcaagatc ggcgaaactg acctgcggca ccagcggtaa agcggcgcta
     5881 atggcacgag aggtacacaa catgcagccc agcatcagac tgaaaccttg tgcacgcgct
     5941 tcagtcgcca gcgccagcgc ttccgtcaga cccccggttt tatcgagctt aatattaacc
     6001 atctcatagc gccctttcag cgccttcaaa ttgctacgag tatgacaact ttcatcagca
     6061 caaatcggca acggatgaat aaaattctcc agcgccgcat cgtcctgcgc aggaagcggt
     6121 tgttcaagca tcgcaacgcc taaatccgcc aatagctggc aacgtgccgc caacccttct
     6181 gcacgccagg attcatttgc atcaacgatc agcgtggcat cgggcacagc tgtgcgaatt
     6241 gccaccatcc gctcactgat aagatggtta tccagcttca ctttcagtaa tttcgcgccg
     6301 gcctgccaga gtgttgatgc gctattggcc atctgatcag gcgtaccgat gactaccgtc
     6361 tgtgcagtgg tgactgtccc gggaagcgtt atgccgatca aatcagccag cgattgctgc
     6421 tgttttcgcg cggccagatc ccacaatgca caatccagcg cattacgtgc tgcgccggca
     6481 gggagaattt tttgcaactc ctcccgtgta agccctttct ctaattgcgg cacgacgctc
     6541 ataatttgcg ccattaccga ggcatcactt tccccataac gcggatacgg cgtgcattcg
     6601 ccggtgcctt taatgccttc ttcttccagt tcaaccacca ccacgtgcgc ttcactgcga
     6661 cttccccggg caatcacaaa cggggtatgt aagggccagg cttcctcaaa taccttaacg
     6721 gttctcatct ttactccttg ttgtcgcggt ggtctgcgga ttaagcgcaa atagcgtttg
     6781 ctgtgttatt gacagttagc ataaactagg tgtgacgtta actatatgta aacaggaaag
     6841 ataatcatgt cacaaaccgt tcatttccag ggcaacccgg ttacagtcgc caattccatc
     6901 ccgcaggcgg gtagcaaagc gcagactttt actctcgtgg caaaagatct gtctgacgtc
     6961 accctcggtc agtttgcggg taaacgcaaa gtgctgaaca ttttcccgag tattgatacc
     7021 ggtgtttgcg ccgtatcagt acgtaagttt aaccaactgg caaccgagat cgacaacacc
     7081 gttgtgctgt gtatttctgc cgatctgccg ttcgcccagt ctcgtttctg cggcgcagaa
     7141 ggtctgaaca acgttatcac cctctccact ttccgtaacg ctgaattcct gcaagcctac
     7201 ggtgtggcaa ttgctgatgg cccactgaaa ggtctggcag cgcgtgccgt tgtggttatt
     7261 gatgaaaatg acaatgtgat tttcagccag ctggtggatg aaatcaccac cgagccggat
     7321 tacgaagcag ctctggcggt actgaaagca taagttaata tgcctgatgg tgttgcacca
     7381 tcaggcatat tcgcgcttac tcttcgttct tcttctggct taagccatat tcccgcaact
     7441 tattggcaat cgcggtatgt gaaacgccga gacgttttgc cagtttgcgc gtgctgggat
     7501 aattgcgata aagctgggtt aataccgagc gttcaaaacg gctggtgatt tcatccagcg
     7561 aaccttccat cgcatcttcg cccacggcta ccgttgcggc gtcataatcc ggcaacaaaa
     7621 tatcctgtgg acgcagctca taaccgtcca gttgtgtcag tgcgcgatag atagcgttct
     7681 ttaactgccg cacatttccc ggccacgcat aacgcgtaag tacagtattc aggtcagcgg
     7741 ccagtttcgg acgcggcacg ccctgctcgt cggcaaagcg ggcgacgaac agctcagtta
     7801 acggcatgat gtcctgcgga cagtcacgta gcggcggcag attgagcgtc aacacgttca
     7861 gacgataata gagatcttca cggaacacgc ctttttgcac cagttcgacc agattcttct
     7921 gcgtagcgca aatcacccgc acatcgacat gcacctcatg gtcttcgcca acccgacgga
     7981 aagtgccatc attaaggaaa cgcagtaatt tcgcctgcat ccgtggtgac atctcaccta
     8041 tttcatccaa cagcaccgaa ccaccgttcg cctgctcaaa gaatcctttc ttcccttccg
     8101 gagcatgacc aaacagttca ctctcgaccg catcttctgg tatagacgcg caattcagcg
     8161 ccaggtaagg tttgcccgct ctggggcttg cctgatggca ggcgtaggca aaaagatctt
     8221 tacctgtacc tgtgtcaccc gtaatcagca gcggcgcgct tagcatcgcc agtttctgcg
     8281 cctgttcgac aacatgcttc attttcgggc tgacggcgac aatttgacta aaggcgctga
     8341 cgtcctgggc ggcaacattt tgcaactgac ggcccatacg aatcgttgat cgcaacatca
     8401 ccaccgcacc ggtcaggacg tgttgatcat tttcatcctg aagataaaca ggcgtaatct
     8461 ccatcaggaa attctgccca ttaataacaa catgctcgtt atgcgaatct tgcggttcgc
     8521 tttccagcca acgtaaaaaa ttaaagccgt taatcaattg tgcggcggta tggttgcgca
     8581 ggcgatccaa tttttgccca aaaagctgac agctcgccgg gtttgccata tccactttgc
     8641 ttttcatatc gacagagagc acaggttcag gcaacgcctc cagtaacgcg ctcaacgcca
     8701 gatgctcacg ttcggaaggc atccacggga cagtacgcac atcggtaaca cctgcaatac
     8761 ggcgtatttc ggccatcaga ctgctgaaac tctcaaactc cagttcagca aaattgaggt
     8821 agattcgccc aatggggtca atctcaatac cgcgtaaatc aatgcctctt agcacgagta
     8881 gatcgagtaa ttcgcgggtc agaccgagtc ggtcttcaca aaagacttcc agacgcatgg
     8941 gaaccttcac ctgaaaaaag aacaattaat atgatgatat gacactattt ggatagcagg
     9001 aaggtttctg tcaacaatca ttgacacaaa gacggaaaaa cgggcacttc ggcgtaaaga
     9061 tatccggtca gcacccgata ttgcattatt tttcgctggg cgttttgcct ttttgcagcg
     9121 tttctttcac ctgaccgata agctgacgac ggaaatcccc gaggcgaggt ttgtcatcgt
     9181 caatccacgg cagcgggcgg caaagctcca tagctttaat cccgagtcgt gccgtcagaa
     9241 gtccagcacc aattccctga gctgcgcggg tagacaaacg agcagcgaga tcttgcgaca
     9301 tccagtccat ccccacttcg cgcaccagtt cgctggctcc ggcaaaagcg atattcagca
     9361 ataccagctt aaacagacgc aaacggctgt aataccccag ttcaatgcca tacagcgtgg
     9421 cgatgcgatt aattaaacgc agattgcgcc aggcgataaa cgccatatcg accaacgcca
     9481 gcgggctgac cgcaatcatc aacgttgatt ccgccgccga acggctgatt tcgcgccgcg
     9541 cctgggcatc taaaactggc tggaccaaat gcgcatacaa actgaccact tcacggtcgt
     9601 tttgcgtttc atggattgag gcataccagc gttgcagcgc tggatgagac tgatcaatac
     9661 ccgcctgctg cgccagtttt tcgcaaaatg cgcggccttt gcccgtgccg tggctgtgca
     9721 acaaatcgcg cgcttcgtcg cgttcatggg cgcgctgtcg caagcgccat aagcgccgcc
     9781 actctgttac cacagaacct acgccagcgc cgataatcaa tgccccagcg gcacatccac
     9841 ccagcgccac ccagtcctga gtttgccagg cattcattgt ccactgtaca ccctgcccga
     9901 caacgcttgc gccaaacaga gccagcccgc ccatcaccat tttgcgccac aggctgcgtt
     9961 tcggacgtaa cgctgcatcc attaccgctt caacttgccc ctcttcttca ggcgcttcat
    10021 cgagcgtggc cggggcaaaa ttttgcgcct gattttcgtc aaaggtctgc tgcgccctga
    10081 attttggatt ctgatcgacc tccagcggac cgtcgaaatc aatacgtggt tttaacggtt
    10141 cggtcatcgc aatttatctc ctattaaaaa ttcaagcgcg gcatcaaggc gaatatgcgg
    10201 cagcggtttg tcgacatcca tcacctgcgg acgaaacgcc tcaaactgga agccttgctt
    10261 atcccagaac gcctgaccgg gcaaacgagc gggaacttcg ccaggataaa cagtgagcgg
    10321 tgcgccatcg ctgagtcgat taccgcgtag cgccgggatt ttctcaccgt taacatcaat
    10381 aatgccgctg gtggtcgcct gcaccgaggc cagccccagg caatccatac taatcccttc
    10441 aaacgccgca ttttgccagg catcctgaat cagttgttgc agtaatgaaa ccatattggc
    10501 gtgctgatcg atggtcacat ggtccgcttt agtggcagca aacaatagct tatcgataac
    10561 cggcgaaaac aaacgccgga acaaggtacg ctgcccgtag tggaaacttt gcatcagctg
    10621 cgtcagtgcc agacgcatat cattaaatgc ctgtggccca ctgttgagag gttgcaggca
    10681 atcaaccagc acaatctggc ggtcaaagcg cagaaaatga ttcttataga accccttcac
    10741 caccttctcg cagtaataat taaaccgctc gcgcagcatt ccggcattgg tgtgcttatc
    10801 ggcctgcgcc agtttggact cgccccaggc atcgacatcc ggccacggga agaattgcag
    10861 cgcgggcgca cctgccatat ctcccggcaa gacaaagcgc ccaggctgaa taaagtgcag
    10921 cccctgctgt ttacagtggt ggagataatc ggtccacgcg gcagcaatgt ctgccagccg
    10981 gttttcgtcg gcaggcgcta gcgggtccag cccttcgcac atcattcgcc atttgaccga
    11041 ccattcgccg cgctgaccat tgagtaagcc cgtcatctgg cgtgaccagc ttaaatagtc
    11101 ctgcgccagc atcggcaggt cgagcaacca ttcgccggga taatccacaa tctccagata
    11161 cagcgtggag gtgtccttga agtggcgtag cagcgaatcg ttcgatttaa aacgtagcgc
    11221 caggcggatt tcactgacgc cgcgcgttgg cgtcggccag gcgggaggat cgccatataa
    11281 ctgcgccagt ccttcatcat atgtgaagcg cggaatgcca aagtcacgct gaggaatgcg
    11341 ttttacgccc agcaggcgct cttcacgcac cgcgcttaac agcggcaagc gtgctccggc
    11401 gtgaatattg agcaactgat tgaccatcgc agtgataaac gctgttttgc cgctgcggct
    11461 tagtccggtt acggcgaggc gcagatgtct gtcgacaccc cgattcacca gcgcattaag
    11521 ttcattttta agtcgcttca ttgctgtcct gtgctgctct gaagaccaga aaaaaatcat
    11581 tcgtaaggat atgaatgtgg gggccaggcc attgattatc aactgcccgt gttgtcatcg
    11641 acgggcgaac tccataagat gtgcagcatt cacgttcgga cggagttcct gacctatgtc
    11701 ccctactatt tatgatattg ccagggttgc aggcgtatca aaatccaccg tatcacgcgt
    11761 gctgaataag caaactaata tctccccgga agcgcgcgaa aaagtgttac gggccattga
    11821 agaattacag tatcagccaa acaagctggc ccgcgcgctg acctcttcgg gttttgatgc
    11881 cattatggtg atttctaccc gttcgaccaa aactacggcg ggtaatccgt ttttctctga
    11941 agttttgcat gccatcaccg ccaaagctga agaggaaggt ttcgacgtga tattgcagac
    12001 gtcgcacaat ccggcagaag acttacaaaa atgtgaaagc aaaattaagc agaaaatgat
    12061 taaaggcatt attatgctaa gttcgccagc ggatgagtca ttttttgccc aacttgataa
    12121 atacgatatt cctgtcgtgg tgattggcaa agttgaaggt caatatgccc atgtttattc
    12181 tgtcgatacc gataattttg gcgacagcat tgcgttgacc gatgcattaa ttgaaagtgg
    12241 gcatcaaaat attgcctgcc tgcatgctcc gcttgatgtc catgtttcag tggatcgggt
    12301 aaatggttat aagcagagcc tggctgcgca taatattgca gtgcgtgatg aatggattgt
    12361 tgacggcggt tatacccatg aaacagcact gcaagccgcg cgggaattat taagccagtc
    12421 accgttgcct gaggcagtgt ttgctactga cagcctgaaa ttaatgagta tttatcgtgc
    12481 ggcagcagag aaaaatattg ctattccgca gcagttagcg gtggtgggtt atagtaatga
    12541 aacgctgtcg tttattttaa cgcctgcgcc aggcggtatt gatatcccaa cacaggagtt
    12601 aggtcaacaa agctgtgagt tattattccg cttaatttct ggaaaaccgt caccacagaa
    12661 tattaccgtt gccacgcata tgacgctgaa ataaatacca gctaccttgc ctgaatgccg
    12721 gatgcgatgc tagcgcatct tatccggcct acatttatag ttcggataaa gtactcgtgc
    12781 cgcatccggc aatttagccc attatcagaa cgagtaattt acgccgacac ctgcataatg
    12841 gaatttatcg ctgtcgcctt cgtcgtgatc ctgccactca aacgcgtatt ccagcgaaac
    12901 ggaaagcccg ttctggaaat cataaccgta aaataaacct acacggttaa aatcatggcc
    12961 ttcacgttca atatcatcct gccagtccca gttactccag cgatccagcc caatgcgcgt
    13021 atacggcgtc accgagtggt tgccgagcgt cagcggcaaa taggcgcgaa tttcttgcgt
    13081 agaaaactca ccgttattgc ggctgtcgtc catattaaag ccgcgctcga gataatagtt
    13141 cactcgcaag gcaaccgttt cgttgaaggt atattgcagg cctgtttccg tttcgactcg
    13201 ggtatcagcg taaccggtcg tgttcagatc gttggcaaat ttatacatcg acaaccaacc
    13261 gttgaaacgt aaatcgtcag tcagtttcac atcccagtct ggcgcgattt tccagcgctg
    13321 catattcgcc gtgtctttac ccggttcatc aacgtagtga taaccataat tacggaaacc
    13381 gccggtcagg ccgaaactga aatcatcgtt ttcgaggaac tgataatgca cctccagctc
    13441 cgggcgatca aaccacgttc cacgtttacc cgcgctataa tctaccggcc cttcctgata
    13501 ataggccaga gcaattctcc acggcccgtt ggcggcatta aaatagactg aaggctccgc
    13561 cagcccatcc atatcttcgc cataaccctc gacgttttct atttcgtaca tcgcgccgat
    13621 attaaagtgc cagtcgttcc tttcctcggc ctgtgcgcag gccattcccg cacacatcac
    13681 cagtgcggta cagggtaata actttttcat tattgttcct tgtattattc tgggggaatg
    13741 ccttccccct gtatttagcg aattgctatt tccgtttctg catcaaagaa atgacatttc
    13801 gtcatatcaa aatgaatagt gatattttct cctgcatgat aatcatttaa cgcaccagca
    13861 cggaccacta actcgtgccc cccaaccgtg gtgtagagca taaattccgc accggttaat
    13921 tctgccacgc taattttggc ggaaatgtta ttttcctctt gcgcgtccgg atgaatatct
    13981 tccggacgta ttcccatcac gatgggctta tgcaaacttc cctgtgtttt cagaaccgct
    14041 aatttctctt cgggaatggt taatttaagc gtttccgtaa cgaatttatc gccatcgatc
    14101 gtgccacgaa taaaattcat cgccggtgat ccaataaatc cggcaacaaa catattcgct
    14161 ggttggttat aaaccgtttt cggcgcacca acttgctgaa caatcccatc cttcataatc
    14221 acaatccgcg tcgccatggt catcgcttcg gtctgatcgt gggtcacgta gatcatggtg
    14281 gtattcagct tctggtgtag cttgctgatc tctgcgcgca tttgcacgcg cagcttggca
    14341 tcaaggttag agagcggttc atccattaaa aacacgcccg cttcgcgcac aatcgcccgc
    14401 ccgagcgcca cacgctggcg ttgcccgccg gaaagcgcgc ccggcttgcg tttcaggtac
    14461 tcacgcaggc cgagaatttg cgccgcccag ttcacccgct catcaatcac ctctttggcg
    14521 attttttgca tcttcaggcc aaacgccatg ttgtcgtaaa ccgtcatatg cggatacaac
    14581 gcgtagttct ggaacaccat cgctatattg cgtgctttgg ctggaacgtc attcattcgt
    14641 ttgccgtcga tcaacagatc gccgccgctg atctcctcaa gcccggcaat catgcgcagg
    14701 gtggtcgact taccgcagcc cgacgggccg acaaacacga tgaactcttt atcggcaatt
    14761 tccaggttga agtccttcac cacatgcacc tggttatcgt agattttttg aatatgttgt
    14821 aacgaaagct gagccatgtt gattcctttg ctatacgttt tgccagaagg ccgataaccg
    14881 cgaccaggtc agagagtccg ttgaaggcaa cagtaattgc gccccggtta agcccgcgcc
    14941 gatccccacc gagcgcatac cgctggcgtt aatggcgtca atgcccgcct gcgcatcttc
    15001 aatgccgata catgcctgcg gcggcacgcc cagcccggca caggcggcga gaaagatttc
    15061 cgggtccggt ttcgagtttt taagttggga agcatccgcg cagaaggtga aaaactcgcg
    15121 cagctccagc gccgctaaaa tcgtcggcgc attcagggag acagaagcca gcccaaccgg
    15181 gatctgctgt gcacggagat ctgccagcaa agagcgaatg ccgggtagaa cagcgctgac
    15241 cgtcaactcg cgcagtgagt ggacatagag cagatttttg cgatacgcca gttgcgccct
    15301 ctcctgcgag ttaaagtcgc cctctttgcc cccgtgttgc agaatgcgcc gcagagactc
    15361 atcgcggctg atccctttta gggattcgtt aaactgcgca tcaatgctga tgccaatttc
    15421 agcggcaatc tgctgccacg cctggaaatg cagatgcgcg gtatcggtga ttacaccatc
    15481 cagatcgaaa attacccctt gcagtttcat tcatcctcct gatgtgtggt agcggtccca
    15541 ttgaagggca aaataaaatc acccaaacag aaaacagatt cttcagccac ggatataagc
    15601 tgaccgttca aacgcagtga aacgggcgca gaagttcgaa tcgcaatacg ctgcgcgtca
    15661 agagtgacct gtaattcgca gccctgccag aacagaggga aagacaactg ttgccactgc
    15721 tcaggtaacg ccggattgag atgcaattca ccgtcacgca cgctcacccc ggcaaaaccc
    15781 tgaatcgccc ccagccagat agcgccagtt gcggcagcat ggataccatc atcacaacta
    15841 tgcggatcag caccaagatc gatttcagtc ccctcgcgcc agaactgata actttgggtc
    15901 agcaggccac agcgtgcggc aacaatgccg tggattgctt tacttaatga cgagtcgtga
    15961 atagtgcgcg gttcataaaa ttgcagattg gcaagacacg atgccgctga gaactgctcc
    16021 ggcagcatgt aattgagcat caccacatca gcttgtttga ggatttgcat ctcgttcact
    16081 tctgcgcgtg aataatccag cagaatggtt tgcttccccg ccgccgcttt gtatttcgcc
    16141 agattaatcg ccggcttagc cataaacgaa tcatcctgcg gcaaaacgcc gtcgggctga
    16201 atttctggca gccgcagttc tttaaggaac atttcggcgc gatggataaa cgcatcgtcg
    16261 ctacagccaa actggcgggc aatactcagc gcctgctgga cgttgtaata cgccatatag
    16321 ctggtgaagg cgttattatt gacatgttcg gtatattcgt caggcccaat aacatcatga
    16381 atttccagac ggtcgttaac cctcaccgcg cggctaatcc agaactttgc agtttccaga
    16441 agtagcgcca tgccttcatg cgcaatgaaa ctttcatccc ccgtggtctg ccagtattga
    16501 ataaccgccc aggcgatatc ggccaccaga tgatgttccg cctgcgccga ggccactttt
    16561 tgccgcagcc cggtgcgaat gttaatggcg gcaaattccg gcgtctcttc ttcgccgctg
    16621 cgcgcgcttt cccacggaaa tagcgcgccc tgccagccgt tgcgtcgcgc tttctcctgc
    16681 gcgcctggca agttgtgcca gcgataacgc agtaaacttc gggcaaccgt cggatcgcta
    16741 aacagatgaa acggtaacaa aaatacttct gtatcccaga aaacgtggcc tttgtagcct
    16801 tcgccggtta agccttttgc cgcaatgctg ctgcgctcgt cgtgggcagg cgtcatgatg
    16861 cgcagatgat aaagcgcata atctaacgct tgctgatcgt gcgcttcgcc gccatttacc
    16921 gtgatacgac gtttctgcca ccattgacgc cagttttctg ttgatactgc aagaagttgg
    16981 tcgtaactct gctgcgcgca catttcaagc tggcgaagcg acgcgctgcc ccactcgtct
    17041 aaaacggctt gcctgtcatc ccgccagtcg atccacacca gtttttgcaa cgtcactgtc
    17101 tcgcctgcat gaagctgcgc actggtatgt tgctgcaaac ggcgctcttt ggcggtatag
    17161 cattgctgca catcaccgct caccatacag caacagctga tggccacatc actgcgtcca
    17221 tcctgggtgg tgtagatccc ctgcatcaga tgctgaccaa acacccgcac ctgggtttcg
    17281 tcgagatgtt ggcgaccgtg gttggtttgc gtggcgtcga tacctgttga aatcagcact
    17341 gacgcgtcgg cgtccagtgg cgtaatagtg atttccagca caatgagcgg cagttggtct
    17401 gccgaaacaa agcgacggct ggcgatggtg taacctgtgc cgttgctggt acgccagaca
    17461 acgctacggc gtaattctcc actggcaaag tcaagttcac gctgccaggc ttcgcgggat
    17521 aacgagaaaa cctcaccatt tatggcaatc tccatcccca agatatcagg caggttcacc
    17581 agttcgttga tttcaccttt tcccgcccga tgatacagcc ccgccagata catccctcgc
    17641 gtctggcgcg tgtaatcttc ttcatggctg gcgcgaagcc caagatagcc gttcccctgc
    17701 gccatcagcg atgcatactt gttcagggta tgctggctga aatggggttc tgataacgtt
    17761 actggcctgg tcataattcc acacgcgtcc ctgtttctgc ggattgatac aacgccgcca
    17821 ccagttgctg gatgatgtac ccctgctcgg cgtcggctat catcacgggc ttgccctgta
    17881 cgtgattgat aaaggcttcc atgctgcgca aatggcggtt gtcgtctgcc agttcccgtt
    17941 gcatcagcgt cattaattca ccgttgttat cggtgtagat atgtgctgga aacagcgtcg
    18001 caccggcttt atcaccacaa aagctgacgt tcataatcga ctgttcgcgg atgttgagtg
    18061 caaatgacgt ttccagccac agaatgccgc cgttatgaaa ttcaatggtg ccaaataacg
    18121 aatcttcgac gctgtaagtt gccggatccc actcgccaaa ttgaccgcag ctcttttgcg
    18181 tgccgatctt ttgaaagcta tgcgcattca cgcttttcac cgccggaaag cccagcacat
    18241 acatcgccgc atccagcata tgaatgccga tgtcgataag cgggccacca ccctgcagtt
    18301 ctttattggt aaagacaccc cagccgggaa cgccgcagcg acgcagggcg cgggcggtgg
    18361 taacgtaaat ctctcccaaa acgccgttgg tcacctgttc acgcagctgt tgcgtatcga
    18421 gcgcaaaacg atggtgaaag tcgtaggcca gcaccttgcc ctgtttgcgc gcggtatcgc
    18481 acatttcccg cgcctgttct ggcgtcatgg cgggcggttt ttcgcacatc acatggcagc
    18541 ccgcttccag tgccatcagg gtatgttcgt aatgaaaacg gttaggtgag cagacgctaa
    18601 ccacatcagg tttcaccgcc agcagcatgg cctgcggatc gtcccacacg gatgcattac
    18661 cgtatttatc tgccagcgcc tgcgcctggg aaaggcggct atcacagaca gccaccagtt
    18721 ccagatcgtt gcgggtgcag tagtacgaag catgaacctt atccgccacc tggcctgcgc
    18781 ctattatcgc gacccgcagc ggagagcttg tcattgcact tttcacaaag acctcttagc
    18841 aggtacgcaa ccaggccaac gaatcacggt acgcctgggc aggatcttct gcccggatac
    18901 gcccttcata caccacataa ccctgatagt tatcggcgcg cagctgttca aacagcgcgt
    18961 ggaaatcgag ggtgccactg cccggctggt aacgatggtt atcggcaata tgcacatgac
    19021 cgagcaggtc acggttgtcg tgcagcgcct gcgccaggtt atcttcttcg atgttcatgt
    19081 gatagaaatc gccgataatc tgcacatgtt taagattgtt ttcgacgatg taacgacgag
    19141 catcggcgag ggtgttgatc atatgatcct gatagcggtt taacggttcg agatacacca
    19201 cggttccggt acgcgcggcg acctgttcca gtacgcgcag ggaatcactc accattttgc
    19261 ggtcgccgtc caggctacgc ggcgaggtca tcggcggtaa gcggaaggta aacatgcccc
    19321 acgctgccgg aacgacgatg cctttacccc ccacttctgc cagcgcttcg agaatgcgtt
    19381 cgatctgctt taagccatta agacgacgct cttcgataaa gtcaccaatc cagccgtcat
    19441 agccaccgca ggtggtggtc accggtaaac cagtttcttt gatcgccgct ttgacttctt
    19501 cgagattgtt gaccagcagt ttgccgtcga tctcaaaacc atcgaaaccc atctctttga
    19561 tataacgaaa tttctccaga atattttccg gaaagaacgc ctgattctgt gtgcctattt
    19621 tcattttttt cattcctttg aattaaaacg taacgcccat tttgatgctc tgttccggat
    19681 gctggtcgac atactgcatg tagctttccg ggctattggc aaaggtcacc accgggtcga
    19741 ttagatcttc acaattgaga taaccgttca tcagcagttc ccaacaggtt tcttcgatac
    19801 gcttgcggct ccagcgcgga taatccgggt tcggttcgct gcacgcgcgg gagaagacaa
    19861 ttttggcgtt attgaaatgg gcttcgcgtc cgaggttaaa accttcggca aacggtttgg
    19921 caaacgcaac atacgagatg gtgccgccat aagccaggcc gcggagcgcc gattgcagcg
    19981 cgtcggcgta accgctggtt tcgataatca catcggcacc ctgcttgccg gtcagcgttt
    20041 tgatctcttt acctacgtca gtgccgatgg ggttaaggca gaaatccgca ccgtggcgac
    20101 gggcaatatc acagcgatgg gcgataggat cgacgccaat taccaccgat gcgccagcgc
    20161 gtttcgccag ttggatggct atttgaccaa tcgcgccaag ccctaccacc accacaaaat
    20221 cacccacgcg cacgttggca tcgcgcacgc cgctcatggc aaactgcgcc gggtcgtaac
    20281 agacggcgtt tttccaggag ctgccttgcg gcattttgcg cagcttgtag ttattcaccg
    20341 cgttaatgat gaccgtctcg gagagtgggc cgtagccgca tacgctgtcg cccaccgcgt
    20401 agtcggttac gtcgctgccg cactcgataa tgtcgccaac caccatgttg ccaagctgga
    20461 atttgccaaa ctcaatgccg cgcggcgcat ctgccggacg cggagtgaac atctgccatt
    20521 caccgttaaa gtcttcatcg ataaacgggc tggcggcgcg gaagtcgacc acttccgttc
    20581 cgtgtttcgg tgcgccgaaa cgcacgcgga ttttcacttc attggctaaa atcgcccgat
    20641 cttcatactc aaccagcgca gcaacacgcg gtgctgtggc tactaacttt ttcatttaaa
    20701 actccttgta aagaaactgg ccgctttagc ccttcacgcc accggcggtc aaaccactct
    20761 taataaaacg ttccgaaagc gcatacataa tcaccaccgg caatgcggtc accagtgagg
    20821 ccgccatcat ccgtccccag atgtaatctg gcgtactgaa cagcgcgttc aggcccaccg
    20881 gtaaggtgaa attgctggcg ctggagagga aaatcgacgc aaacagatag tcgttccacg
    20941 ccaccataaa gcagtagacg aacacggata tcagcccgga catcgccaac ggcacggtga
    21001 tgcggaagat aatttgcaga cggttgaggc catccatcat cgccgcttct tcgatctcat
    21061 cggggatggt gtcgaagtag cttttcagca taaacacggc ggtgggcaga gtttgcgtca
    21121 ccatggtgat gatcagcgcc atctcggtgt cgtaaatgcc cagcgcggtg atgattttga
    21181 acagcggcac caccagcaaa atgccagaga acatatacac cgtgtaaaag ctggcattga
    21241 tggtcatccg acctttaaag cgcaggcggg aaagcgcgta agccccaaga atgccgagga
    21301 ataccgccac cacggatgaa accaccgaca ccaccagact gttacggaag tagtcgacaa
    21361 acgggaaaat catcgggtta aaaatgtcga cgtaatgctc cagcgtccac tgctgcggca
    21421 gcagcgtagg atgcagtgag atcgcctctt tcgcgccctt gaacgaggtc atcagcatca
    21481 caaaaaatgg aaacagcgtg atgatgagaa acagcgccag cccgcagtaa aaaccgatgc
    21541 gactgagtgt gcgtttattt gttgccattg aggttcaccc gtttcctggt cagcagaatg
    21601 acagcgaaaa taatgatgaa gagcaccacc gagatcgccg ccgcttttcc taaatcatta
    21661 aaggcaaagg cggttttgta gagatataca ccgagaatat cgaccttggt cgtcagcaaa
    21721 taaacatccg cgaacatgta gaacatccag atggtgcgca gggtcaccac cgtcgccagg
    21781 accggcataa tcgcgggcag cgtgacgata cgaaaccgtt gccaggcatt agcgccatcc
    21841 atctctgccg cttcgtacag cgatttgtcg atggtctgca aaatcgccag aaacgagata
    21901 aaggcatacg ggaagtagcg ccagatggcg aacagcacca ccagcacaaa gctactgccc
    21961 ggattatcga accacagcgg tgcctgctca tagagatgca gaagatcgac gccgaggtag
    22021 ttcacaatgc cgtagccgtt gttgaacatg tatttccagg caaacaccag cgaaatggac
    22081 ggcgttacgt aggagaggat caccagcgaa cgcgcggttt tgcgcagacg gaactcgcgg
    22141 ttgaaaaaca tcgccactgc cagcccgagc acggtgctgc ccgccaccac cagcgcggta
    22201 taccagaccg tcatccacag cgagtgccag aagccgggat cggagaggat acgcacatag
    22261 ttactcaccc caacaaaggt tgactcgatg ttgggattga gcggcagacg taaaaaactg
    22321 atttcgatat tcgacaccat cggccacgcc accagaccgc ccagcagtaa taagctgggc
    22381 gcgagaagca acagcgcaaa gggcatatcg gaacgacctg aaaaaagcct gttcattgcg
    22441 gattcctgtc cggggtttag tgctgttcga tcagttcatc cagctttttc tggctcgctt
    22501 gcagcgtgcc agggagatcg gctttaccca cggtgacgtt atgcaccatg gagctcacca
    22561 ctccagaccc cgtcacatca cccatgcggg taaagttttt atcccctact gcaccaaaga
    22621 cctgaatatt tggcagttca ccgattagct gattcggtag ttcacccagc gccttaataa
    22681 cgtcgttgtc tttccaggtg gcggtagtga caaccgcttt attcaccggc agcgcagcac
    22741 ctggcgacat catcacccag tcggcaatgt tgtctgcctg ctccataaag gtgacaaatt
    22801 tttctgctgc ttccgtctct tcggtctttt gcccggcggt aatggtcagc gaggtcaaca
    22861 tgccgtagac cgcagagttt ttctcggttg gcaccacgaa accgacgttt ttcgggtcgc
    22921 cttctttaat cacagccgga aggatatagg tggagtaaat cgccatcggc gcggtgccgt
    22981 tcataaaggc gtctttcact tccatgatgt cgttagaacc cggcatagtg ttggcagcaa
    23041 ggtcgcggta ataggtcagt gcctgcatca tctctggtgt atcaagggtg attttgcctt
    23101 cggcgttaaa gacgttagcc tggttggata acgcaaactg ggagaaggat tgttccgtca
    23161 acacgctttc tgctgtaggc agcgcaatgc cgtatttttt attcgccggg tcattcagtt
    23221 tctgtgcaac gtccagcagc tgttgccagt ttttcggctc ctcaagcccc gcttttgcca
    23281 gcacatcttt gcgataccag ataccgccaa tccaggcgct gacaggaaca ccggtccatg
    23341 cgctaccatc ttcggtacgc acaatacgca gtacgccatc gtaaaacgcg ccttcaccaa
    23401 cgttgctgat gactgtggca accgctttgc gatcgataag ctgctctttg tccatcactt
    23461 tggcgtagtc atggctggtt tcgatcactt ccggcagcga accgctacgt gaaagagtaa
    23521 tgactttagt gttataggca tcttcttcca cgggcacttg cttaacggtg atgccagggt
    23581 tttctttttc aaaacgggca atcaatttac tgataacggc ctggcgctcc tgctccaccg
    23641 aagaatgcat aaattcgatg gatacattcg ttttattttc ttctttacag cctgaaatca
    23701 gggcgcagga aaccagtgct gataacagca cgatttttga tttaatcatg agatgttcct
    23761 ttttatttaa tccacataac ctgccagggg cgcagcgtta tttcattacc caatatatca
    23821 acttcactaa tcagatcccg accatgcaga ttagtaatat ttacatgctg aatattttta
    23881 ctgacattaa acaatccagt cagacaatta ccatcagcgt tacttctttg aatacgcatt
    23941 acggatgaat taatcgtatc aatggtaaaa ttattatccg gatgaaactc gttatggctg
    24001 cgacgaagtg taattaaacg cgacaactca tgatataccg catgccttaa tgtagcttca
    24061 tcgttcagtt ctcgggttat ctctttactg tgatattttt tacggttaat cgcacggtta
    24121 tatccgagtt tttcgacacc tgcgtaatca ttacgcgagc caagaatact ttgaatatat
    24181 atcgctggca caccggggaa acttaacaaa atcgcatggg cgagaataaa cctggcgcaa
    24241 cgttcttcat cgctactctc acggcggctt aacgcatcca tataggtcac atttatttca
    24301 tacggactgc gtgtaccgtc gggattattt ttccagttta ctaatgcacc ttcctgctgt
    24361 aacgcctcga ccagctctaa tatttcgctt tcaggcaaca agccccgtag cgggtttagc
    24421 ccgatgccat cgtgagaggc gaggaagtta aaccaggtgg tgttgctgga aggtagtgtc
    24481 aggttttgcg cccacgcaca aagcgcctca acgttctgtt tttgcaccgc atgcagcacc
    24541 agtggcggca gcgagaactg gtacaccata tgtgcttcgt catcgcctgc gccaaagtaa
    24601 gcaatgttgt ctttatgcgg aacattggtc tcggtaatga tcactgtacc tggcgcaacg
    24661 ttatcaataa tcgaccgtaa cagtttgata atcagatgtg ttttttccag atggatgcag
    24721 cttgttcccg gctctttcca cataaagcca acggcatcca ggcggacata ctcagcacct
    24781 ttcgcaaggt aacagagtaa aacatccacc atcgccagca acacttcagg gctacggtaa
    24841 ttcaggtcaa tttgatcgtc actaaaggtg gtccataaat ggcgcgttga atgatcgcgc
    24901 atctggaatg gcgttaataa cggtaacgca cgcgggcgag tgacggcgct gagatcggtt
    24961 tgcgggtcaa cggcaataaa aaaatcttca aaacctggat gctgttgtaa atagttttta
    25021 aaccattcac tttttgccga catatggttg cagacaaaat caaacattaa atgactacat
    25081 tcaccgagtt gctgaatatc ctgccactcc cccgcttcac tggcgacctg ttgataatca
    25141 attaccgaaa agccatcatc agatgaccat ggataaaacg gcaacaaatg aacatgtgaa
    25201 aaaatgcttt gcagccattg atggtaaaac tgattaaatg tgggtaatgg ttttaaatca
    25261 ttgctgtgaa attgatcggc ataggtaatt aacacgacat cactttcatc ccagtgtttt
    25321 ttacgtcgct gtgtaattaa tcgtttcgca ctctcaagac gcgttacaag tttctgtaaa
    25381 tgagttgcgg taaatgttcc accgtagatt tcgtccaggt aatccgtaat tttctgtttc
    25441 atgttgcctt tccgtggtag cggtcccatg aaacgagaga ctactccgca gaaaataaac
    25501 tgtcaattga gcacaagggt tttagtcacg caggaaatca ttttttacca gggaaaaagc
    25561 gtatttgtga gctgacgcaa ataatctatg gggatgtaaa taaggtgtga cagaaaaaaa
    25621 acggcgcata agcgccgctc atggtgaatt cttttaacct ttgaccttcg gcattgcgat
    25681 gtctttcagg ccaccggcgt tctcaacgtg ggtatatccc atctcgctaa ggatctcttt
    25741 tgcttgccct gactggcgtc cggcattgca atacactttc acggtgtcgt ttttatccgg
    25801 aacggcggtg gcaatgcgct ctttcacttc cttcagggga atattgatgg ccccctgaac
    25861 gtgctcttgc tgatactgct ctggaacacg aacatcgatc cagtgttcag cggcgaaaac
    25921 gggcagtgaa aacaccagtg ccagagcaag taagcctttt ttaaacatgt aagcgtcctt
    25981 ctatggatga aaattgccat ccattatacg cctgagattt aacaattttt gcgaaactcc
    26041 cctcaccttt tataacgctg tgccagttta ttagcagccc gacttaacag cggttccagc
    26101 gccacagcca gcaacatttt cagcggtcgg cgagcaactg attttatcgc ccagcccgcc
    26161 acacccgccg ggccatagcg cagtgcggta agaagtacca gcttgcctgc taatttgaaa
    26221 ccaggcttta ccttttgccc ggcctgttgc cagcgagtat tcataacttt cctcacagtt
    26281 gacggaaacg gctacgtaac gtgaaagtat cggaagtgac ataacgttcc atctcgcgta
    26341 aacgcgtttc acttgccgcc agttcacggt cgacttcatc cagcaattcg ctgctggaag
    26401 gtagctgctc accaaaggcc atgttgtccg gcattggatc aagcgcaaat gacaaaatga
    26461 tgtaagcaac cagggtaaac agcgccagac cgaagaaaat cgacagcacc accaggatac
    26521 gcaccagttt taccggtaca tcaaaatagt tggcaatccc ggcgcagacg ccgcggacca
    26581 tgccctgctg tggaatacgc cataattttt tattgagatt aatgcccgcc attagcgatc
    26641 cctccagttc ggatgttctg catcaagaat agattccagc gcctgaatac gttcgcgcat
    26701 ccgttttgct tcatcagcca gttgcgctaa tcgctgctgc tcactttgcg acaattcact
    26761 gcgaccagaa cgattgctgt aatgcagcca taaccagatc ggtaaaacaa acagcacaaa
    26821 aatggttaac ggaatagcca gaaatagcgc gctcataagt actccttaga cgatgagcgg
    26881 cggcgcgttc ggacgccgcc tggatgttat tattgattgt cttgcttcat tttggctttt
    26941 aattgtgcca gttgttcgct gattgcatca tcggctttca gttcggcaaa ctgatcgtcc
    27001 agcgattttt gtttaccgaa gctgtggctt tctgcttccg cttccatctg gtcaatacga
    27061 cgttcgaaag attcgaaacg agccattgct tcatccagtt tgccactgtc cagctgacga
    27121 cgcacatcgc gcgacgagtt tgccgcctga tgacgtaaca tcaatgcctg ctggcgagcg
    27181 cgtgtttcgc tcaatttgtt ttccagctca ccgatctctt tcttcatgcg tgccagcgtg
    27241 tcgtccacca gcgtcacttc atgttccagg ctcttaatca gatcggtcag tttctgtttt
    27301 tcaattaacg ctgcacgtgc caaatcctct ctctctttca gcagcgccag ttcggctttt
    27361 tcctgccatt caacttcacg cgccgacgct tgttcaatac ggcgagtcag ctgtttcttt
    27421 tctgccaacg cacgcgccga agtagaacgt acttcaacca gtgtatcttc catctcctgg
    27481 atcatcagac gaaccagttt ctgtggatct tccgctttct ctaacagagc gttgatgttg
    27541 gcattcacga tgtcggcaaa gcgagaaaaa atacccataa tgttgtcctc ttgatttctg
    27601 cgttcaggat tgtcctgctg aactgttaat acaatttgcg tgccaatttt ttatcttttt
    27661 gatttataaa gatctgattg aagaatcaac agcaacatgc caggatgagt tagcgaatta
    27721 cactaacaag tggcgaattt catcatggca gaatacaaag ataatttact tggtgaggcg
    27781 aacagctttc tcgaagtgct ggaacaggtt tcgcatctcg caccgctgga caaaccggtg
    27841 ctcatcatcg gcgaacgcgg caccggtaaa gagctgattg ccagccgcct gcattatctc
    27901 tcctcccgtt ggcaagggcc gtttatttcc cttaactgcg cggcgttaaa tgaaaatctg
    27961 ctggattccg aactgtttgg tcacgaagcg ggggcgttta ccggtgcgca aaaacgtcat
    28021 cctgggagat ttgaacgtgc cgacggcggt acgctatttc ttgatgaact cgctacggca
    28081 ccgatgatgg tgcaggagaa attattgcgc gtgattgagt acggtgaact ggagcgcgtt
    28141 ggcggcagcc agccattgca ggtgaatgtg cggttggtat gcgcgacgaa tgccgatctc
    28201 ccggcgatgg tcaatgaagg cacttttcgc gctgacctgc tcgaccgact ggcttttgat
    28261 gttgtacaac tgccaccact gcgcgagcgc gaaagcgaca taatgttgat ggcagaacac
    28321 tttgccatcc agatgtgtcg ggaaatcaag ctgcctctgt tcccggggtt tacggagcgc
    28381 gccaaagaaa cattgctgaa ttatcgttgg ccgggaaata ttcgtgaatt gaaaaacgtg
    28441 gtggaacgtt cagtgtatcg ccacggcacc agcgattatc cgcttgatga catcattatt
    28501 gatcccttta aacggcgtcc gcctgaagac actatcgccg tttcagaaac cacctcgctt
    28561 ccaacactgc cgctggattt acgtgagttt cagatgcagc aggaaaaaga gttgctgcaa
    28621 ctcagtttgc aacaagggaa atataaccag aagcgcgcgg ctgaattact ggggttaact
    28681 tatcatcagt tccgcgcgtt gttgaaaaag caccagattt agcgaagttg agcaatacaa
    28741 cttgccggat gcggcgtgaa tgctttattc ggcatacata atcaatacgt cgtttgcagg
    28801 cctgataagc gcagcgcatc agacattatt gcgttgggct attaatcgct cagcgcatcc
    28861 tgcaaaattt tcattgccgc atcgaattgc gcatccggga tggtcagcgg atacaggaag
    28921 cgaatcacgt tgccgtatgc gccacaggtc agcaggagca gcccctgcgc cagcgcgcgt
    28981 tgctggattt tctgtgcaat cgccgctgac ggctcgcccg tttgcggatc gttaaactct
    29041 gccgcaatca tcgaccccag gccgcgtacc gcagcaatgg ccggaacgct ttctttggca
    29101 tcaatcaacg tgtttttgag acgctggccc agttgattcg cgcgttcgca gagtgattct
    29161 ttgtcgataa tattgagcac cgcgtgcgcg gcagccaccg ccagcgggtt cccggcgtag
    29221 gtgccaccca acccgcccgg cgcgggcgcg tccataatat tcgcgttacc gaccacgccc
    29281 gaaagcggca tcccgcccgc gaggcttttc gccatcgtca ttaagtccgg cttatcggcg
    29341 taatgatcca tggcaaacag tttaccggta cgcgcaaagc cgctttgcac ttcatcggca
    29401 atcatcacaa taccgtgctc gtcgcacagg cggcgaatgg cggcaaccag ctcttttggc
    29461 gcaacgttga aaccgccctc gccctgcacc ggttcgaaaa taatggccgc gacctgcttc
    29521 gcttcgatgt ctgatttaaa caagcgttcg atggcgtcga gggagtcctg tgttgaaatg
    29581 ccgtgtaaat ctgacggata aggtacgtga tacaccgaac cagggaacgg gccgaagccg
    29641 attttgtacg gcgcaacttt tccggtcagc gccatggtca tatatgtacg accgtggaag
    29701 ccaccgctaa acgcaatcac gccaggtcgt ccggtatggg cgcgagcaat tttcaccgcg
    29761 ttttccaccg cttccgcacc ggtagtgaag aatgcggttt tagcctgccc gctcactggg
    29821 gcaagggcgt taattttctc cgccagcgtg acgtagcttt cgtacggcac aatctgatac
    29881 gcggtgtggg taaactgttg caattgctgc tccaccgccg cgaccagatc agggtggcga
    29941 tgcccggtat tcagcaccgc aatgcctgcg gcgaaatcga tgtattcgtt gccctctacg
    30001 tccttcagcg tagcgttttc tgccgactgg gcgaagaagt tacacatcac gccaaccccg
    30061 cgtggggtag cagaaagacg acgctgatgg aattcattgt tgctcatgtt tcacaccttt
    30121 tgactcttca ctgttaatcg gaaattaaac gcccagacga tcgcgcaggc tgtaataagc
    30181 cgcgcccatc gcggtaaatg gcacgcgcag cgtgcgcccg ccggggaacg ggtaatgcgg
    30241 cagattggcg aaggcatcga aacgttcggc gtcgccgcgc agcagttcgg caatcagacg
    30301 cccggcaaga tgggtacagg tgacgccgtg gccgctgtag ccctgcatgt aatagatgtt
    30361 ggtatcaagg cgaccgaact gcggcatgcg cgacaaggtc agcaggaagt tgcccgtcca
    30421 gcggtaatca attttcacgc ccttcagctg cgggaaggtt ttcagcagtt tcggcaccac
    30481 aaggcgctca acgtcatccg ggtcgcgcgc gccgtagacc acgccgccgc cgtacagcag
    30541 gcggttgtcg gcggtaagac ggtagtaatc aagcagatag ttacagtctt ccacacagta
    30601 gtttttcggg atcagcgaac gggctaaatc ttccgacagc cgttcggtgg tgatcacctg
    30661 cgtgccgcac ggcatgctgc gtttcgccag ttccggctct actttatcgc ccagatacgc
    30721 attcccggcg acaatcacat acttcgccgt cacctgacct ttggcagttc gcacaacggc
    30781 tggcgtggtg tgctggatct gcgtcacggc agaaagttca tacacgcgcc cgccgttgag
    30841 gcggatggcg tccgcttcgc caatggcgag gtttagcgga tgaatatgcc caccgctgtg
    30901 atccagcagc gcaccggtat agcgatcgct ggctacttca cggcgaatgg cgttggcgtc
    30961 cagcaattcc agctgtttat tgccgtagcg ttcccagttc tctttctgct cttcaagtgt
    31021 ggcgagctgt ttatcattca tcgccacaaa caggccgccg gggcggtagt cgcagtcaat
    31081 ctgataacgt ttgatacgtt cgcggatgat ctcaccacct tcgaacatca tgctgccgag
    31141 catacgggcg gtgtccatgc cgtagctttt ttcgatcacg tcgatgtcgc ggctgtagga
    31201 gttcacaagc tgcccgccat tgcgcccgct tgcgccaaag ccgatgcgtg aggcttcgag
    31261 aaccactacg tcaaagcccg cttccgccag atgcagcgcg gaagagagcc cggtatagcc
    31321 gccgccgacc acgcaaacgt cgcaggaaat cgactcattc agcgtgtcga atggcgcgta
    31381 tttattcgca ctggcggcgt agtaactgct ggtatgttcg gtcatttcag gcctccaggc
    31441 ttatccagat ggttttcagt tcggtgaatt tttcaagggc atgcagggat ttgtcgcgac
    31501 cgttgccgct ctgcttatag ccgccaaacg gcacggtcat atcgccgtcg ttgtagttat
    31561 tgacgaagac ggaaccagcc ttcaggcggc ggctcatgcg gtgcgcgcgg gagaggtcgc
    31621 gcgtccatac cgccgcgcca aggccgtact ggctgtcgtt ggcaagctgt agcgcctggt
    31681 cttctgatgt gaaacgcgtg accaccagca ccggaccgaa aatctcttcg cggcttaagg
    31741 acgcattcgg gtctacatcc acaaagatgg tcgggccgat ggcggcagcc agctcagcgt
    31801 tacgaccatc cagcagcagt tgccctttgc tttcgccttc ccgaataaag ctatggaccg
    31861 agtcggcgtg ggcgcagtcg attaaggtgc ccatggtggt tgcgggatca agtggatggc
    31921 ccggctgcca gttttgcgcc tgctgtttta acagggctaa gaattcatcg gcgatgctct
    31981 cttccagcaa caaacgcgtt ccggcgatgc acacctggcc ctggttgtag aagatgcctg
    32041 cggcggtggc gcttgccgct ttttgcagat ccggacaatc ggcgaaaacg aggttggcgc
    32101 ttttgccgcc cgcttccagc cagacgcgtt tcatgttgct gtcgcccgca tctttcagca
    32161 gctgtttccc ggtacgggtt gaaccggtaa aggcaatggc gtcgatatcg ttatgacgcg
    32221 acagcgcctg ccccgcttca tgaccaaaac ccgtcaccac gttcaacaca ccatccggca
    32281 agcctgcttc tttcgccagc cccgcgagac gaatcgcact gagcggtgat ttttcagacg
    32341 gttttagaat cacgctgttt cccgccgcca gcgccgggcc gagtttccag caagtcagca
    32401 acagcgggaa gttccacggc acgatggcgg caatcacgcc gaccggttca cgcacgatca
    32461 tcgccagctc atggctactg gtggtcgcca cttcgccata cactttgtcg atcgcttcgg
    32521 cgtaccagcg aatggcgcgc gccgcgccgg gaatatcatc acgcagactg tgacgaatcg
    32581 gtttgccggt gtcgagagtt tccagcagtg ccagctcttc ggcgtgggct tccattaaat
    32641 cggcgagttt attcagtacc gctttacgtt tagccggaga agagagtgac cagtcgccgc
    32701 gttcaaatac accgcgtgct gcgctcaccg cacggtcgat atcgacgctc ttgccgcggg
    32761 caattttcgc cagcggtgcc tgggtgaccg gatcaacggt ttcaaaggtt tcattttccg
    32821 ccgcagcagt atattcaccg ttaataaata agcggttttc aatggcgaga cttaacgctt
    32881 tatcctgcca gtaagccaga tgatgaaaat tcattatgac tcctgtttca cgtctatcag
    32941 atatatgcag tttgtgaacg tcagggcgca gagatccccg ggccgtatgc ccgtttattt
    33001 ctggcgacat tctttatata cacttcatcc ttcaagccgc ctctgccttg gctgcgttcg
    33061 ctcccccgaa tcacttacct gagtaagctc atcgggattc gctcacttgc cgccttgatg
    33121 caacttgaat gattttgtgt atagattgcc gggcgcattg cgcttacccg gcttacagaa
    33181 caaaaagatt aaaacgtggt gggcgtatgg gcgctgataa ttcggcaaat acctgccgac
    33241 gtattactga aactgtgcgg tatgccggta ttaatggcat aactttgccc cgcgacgagg
    33301 tggtaatcct gaccattaat cgtcagaaca atttcacctt ccagtactgt gcctatttcc
    33361 tcaccctgat gcttaattct ttccccagtg gttgtgcccg gctggtacgt ttcaaagatc
    33421 atcgccagcg tgcgattcgg gttaccgtta tgaaccagct tcattgacac accctgactg
    33481 cccatctcaa ttaagtcgtc ctgattaatg acgacctgcg gctcatcagg tttttccggc
    33541 tcggaaaaga attccgagag tgacagacca tacaccttca gcagcttttg cagcgtactg
    33601 atggcagggc tgactttatc ttgttctatc gtactgatag cactgtgagt cagcccggag
    33661 agttcggcgg cacgacgttg tgaaagcccc tgctgctggc ggatttccga caagcgtttt
    33721 cctggcgcca gtccctcatc actcatattt gcatttcctt aaactgtagt ggtcagagtc
    33781 gctgtttttc agcgatatgg tgctgacaag cggtgataaa gccctcgaac aatatacgcg
    33841 aaagcgcgta ctcgctactg ttccattccg ggtgccactg tacgcccagc gcaaaaggat
    33901 gattgatgac gctaaccgcc tcaactaagc catccggcga gcgagcttca acacgcaacc
    33961 gtgggctaac gaccttcgcc ccttgcccat gcagagagtt tacccaaaag ttgctacatt
    34021 caggtaacaa cgcagacagt aatcccccct cttcaacctg aacttcatgc gacggtgcat
    34081 attgctgttc caccggcagt tcgggatctt cccgatgttc cagcaattca ggctgttcgc
    34141 acagcttgcg atgcaacgaa ccaccggttg ccaccaccag ttcctgtaaa ccccggcaga
    34201 tggcgaaaat ggggatgcgc ctttcgagtg cggcattaat taacgccatg ctcagaagat
    34261 cacgcccggg atcggcgtca ggctcatcgc cgttttcacc atataggtgc ggctgcacat
    34321 tgctgggact accaggaaga taaatgccat cgagtttcgg caaaagttgt tcaagtaatg
    34381 acggttccgc cagcgcatgt ggtagcgcaa ttggcaagcc gcctgcgtgg atgatggcat
    34441 tcaggtactt ttcttgcaga gtctgggtcg catgaccctt aagcctgttc ctgcacatta
    34501 cgacaccgat aaccggattg ttcattatat tttccatgct caatctcaca aagtggacta
    34561 aattatcgcc attactgcgg tttaaatgac ctttatgttc aatatttttt caatctagca
    34621 gtgggttttc atttttgcaa actcaattta acatttgaca aacatttagt ttgcatacag
    34681 attcgaatgg tggtcattat attttacgct ttgataacga gcggaaaaca aaccaaaggc
    34741 gaagaatcat ggaaaccaat atcgttgaag tagagaactt tgttcagcag tcagaagaga
    34801 ggcggggtag cgcctttacg caggaagtga aacgctacct ggagcgctac ccgaatacgc
    34861 aatatgttga tgttttactt actgatttga atggttgctt ccgtggaaaa cgtatccctg
    34921 tttcaagcct gaagaagttg gagaaagggt gttatttccc ggcctcggtg tttgcaatgg
    34981 atattctggg caacgtagta gaagaagcgg gtctgggtca ggaaatgggc gagccggatc
    35041 gtacttgtgt tcctgttctc ggttccttaa ccccttctgc cgccgatcca gagtttatcg
    35101 gtcagatgct cctgaccatg gtcgatgaag atggcgctcc ctttgacgtt gagccgcgga
    35161 acgttcttaa ccgcctgtgg cagcagctac gccagcgcgg attgttcccg gttgtagcgg
    35221 tagagctgga gttctattta ctggatcgtc agcgcgacgc tgaagggtat ctgcaaccgc
    35281 cctgcgcgcc cggcaccgat gaccgcaata cacaaagcca ggtttactcc gttgataacc
    35341 tcaaccactt cgccgatgtg ctcaatgata ttgatgaact ggcgcagtta cagttaattc
    35401 ccgccgacgg tgcggtcgcc gaagcctcgc cgggtcagtt tgaaatcaac ctttaccata
    35461 ccgataacgt gctggaagcc tgcgatgatg cgctggcgct aaaacgcctg gtgcgtctga
    35521 tggcagaaaa gcataagatg cacgccactt ttatggcgaa gccgtatgaa gagcacgcgg
    35581 gcagcggaat gcatatccat atcagtatgc aaaataaccg tggcgagaac gtgctttctg
    35641 acgcggaagg cgaagattcg ccgctgctga aaaagatgct cgccgggatg attgacctga
    35701 tgccgtcgtc gatggcgttg ctggcaccaa acgtgaactc gtatcgccgc ttccagccgg
    35761 gaatgtatgt gccgacgcag gcgtcgtggg gccataacaa ccgcaccgtc gccctgcgta
    35821 ttccgtgcgg cgaccgtcat aatcaccgcg tggaatatcg cgtggcgggt gccgatgcca
    35881 acccatatct ggtgatggca gcgatttttg ccggtatttt gcatggcctt gataacgagc
    35941 tgccgttgca ggaagaagtc gaaggcaacg ggctggaaca ggaaggctta cccttcccga
    36001 ttcgccagag cgatgccctg ggtgagttta tcgagaatga tcacctgcgc cgctatttag
    36061 gcgaacggtt ttgccatgtg tatcacgcct gtaaaaatga tgagctgttg cagtttgagc
    36121 gcctcatcac agaaacagaa attgagtgga tgttgaaaaa cgcgtaattc cccatgcggg
    36181 gttgtttcat cggcctgagc ggagccaggc ctgacatttg ctggtaatcc agacatttcc
    36241 cggatgtcgc gttatggagc gcaggcggca acgggcttcc gttaacgatt aagactgtga
    36301 cgaggaaatg agatgatgcc gatgattaaa tccccgcatg gcgagggagg ctgcgtatgc
    36361 gcccctcctg ctactgactg gactccgccc cctttgcttc ccttgctaaa caggtttgat
    36421 ttcaggtcga cacgaccgca aaccttatta cgcaggggag gcagcaatta tggctattaa
    36481 ttcaccactg aatattgctg cgcaacccgg caaaacccgt ctgcgaaaat cactgaaatt
    36541 gtggcaggtg gtaatgatgg gtctggccta tctcacgccg atgaccgtat ttgatacttt
    36601 tggtattgtc tccggcatta gcgacggtca cgttccagcg tcctatttgc tggcgctggc
    36661 gggcgtgctg tttaccgcta tcagctacgg caaactggtt cgccagtttc cggaggccgg
    36721 ttcggcctat acctacgcgc aaaagtcgat taatccgcac gtcggattta tggtcggctg
    36781 gtcatcactg ctggattatc tctttttgcc aatgatcaac gttttgttgg cgaaaatcta
    36841 tctctccgcc ctcttcccgg aagtgccgcc gtgggtgtgg gtggtaacct tcgtcgccat
    36901 tttaaccgcc gcgaatctga agagcgtcaa cctggtcgct aacttcaata ccctgtttgt
    36961 actggtgcaa atctccatca tggtggtgtt tatcttcctg gtggttcagg gactgcataa
    37021 aggagaaggc gttggcaccg tctggtcact tcagccgttt atcagcgaga acgcgcacct
    37081 gatcccgatt attaccggtg cgacgattgt ctgtttctcg ttcctcggtt tcgatgcggt
    37141 gaccacgctt tcggaagaga cgccggacgc cgcacgcgtg atcccgaaag ccatcttcct
    37201 gacggcggta tacggcggcg ttatctttat cgcggcgtcg ttctttatgc agctgttctt
    37261 tcccgatatc agccgcttta aagacccgga cgccgcactg cctgaaattg cgctgtacgt
    37321 cggcggtaag ctgttccagt cgattttcct ttgcaccacg tttgtgaaca cgttagcgtc
    37381 tggcctggcc tcacatgcca gcgtgtcacg tctgctgtat gtgatggggc gcgacaatgt
    37441 gtttccggag cgcgtgtttg gctatgtgca tccgaaatgg cggactccgg cactgaacgt
    37501 cattatggtc gggattgtcg cgatgtcggc gctgttcttc gatttagtta ccgccacagc
    37561 gttaattaac ttcggcgcgt tggtagcgtt taccttcgtt aacctgtcgg tgttcaacca
    37621 cttctggcgg cgcaaaggaa tgaataaaag ctggaaggaa cacttccact atttattaat
    37681 gccgctggtt ggcgcgctga cggtgggcgt gctgtggatt aacctcgaag ccacctcgct
    37741 gacgctgggt ctggtatggg cttcgttagg cggcgcatat ttgtggtatc tgatccgccg
    37801 ctatcgcaaa gtgccgctgt acgaaggtga cagaacgcca gtgagcgaaa cgtaatagtc
    37861 ggatgcgcgc cgcattatcc tgcctgaggg taatgcgccg cgccattaac tataaaaaga
    37921 tgtatgaccc ggatcacgag tgctatcatc cgcccttatg cttagcgcat taaccccagg
    37981 ggcaaataat gaaccacgat atcccgctaa aatattttga tattgccgat gagtacgcga
    38041 ccgaatgcgc agagcctgtc gcagacgctg aacgcacacc gctggcccac tacttccagt
    38101 tactgctcac ccgtttgatg aacaatgaag agatcagcga agaagcccaa catgaaatgg
    38161 ctgctgaagc ggggattaat cccgtacgca ttgatgagat cgcagagttt ttgaatcaat
    38221 ggggtaatga gtaattattt aattgcagac gatcggtcag tatcgttgtc cggataaagc
    38281 gttcacgccg catccggcta acaatgacac gcactgcagc gtgctttaat gggtttctca
    38341 cgatcgtacc gctctgctcc tcgctaagtt gttctgtgag ttatagttat agagaaatca
    38401 cgggtacgaa tgttgaacag atggcgacgc cacctgttca acgaccaacc acacggccct
    38461 cattacgacc cctgaacaca aacggtaatg gcaaatgtca ttaaatatta gtaagatagc
    38521 ctctttacat aaaatccctt aatattatgc gccaggtatt atcgtctctt ttggtgattg
    38581 ctggacttgt gagtggtcag gcaatcgccg cgcctgaatc ccccccgcat gctgatatcc
    38641 gcgacagcgg ttttgtctat tgcgtcagcg ggcaagtcaa cacctttaac ccatccaaag
    38701 cgagcagtgg gttaattgtc gatacccttg ccgcccagtt ttatgatcga ctgctggatg
    38761 tcgatcccta tacctatcgc ctgatgccgg aacttgccga aagctgggaa gtactcgaca
    38821 acggcgcgac ctatcgcttc cacctgcgtc gcgatgttcc gtttcaaaaa accgactggt
    38881 ttactcccac tcgtaaaatg aatgccgacg atgtggtgtt taccttccag cgaatttttg
    38941 accgcaacaa cccgtggcat aacgtcaacg gcagcaactt cccctacttc gacagcctgc
    39001 aatttgccga taacgtgaaa agcgtccgca aactggataa tcataccgtt gagttccgac
    39061 tcgcccagcc ggatgcttct tttttgtggc acctcgcaac ccattatgct tcggtcatgt
    39121 cggcagaata tgcccggaag ttagagaaag aagatcgcca ggagcaactc gaccgtcaac
    39181 cggtcggcac cggtccgtat cagttgtcgg aataccgcgc cgggcaattt attcgcctac
    39241 aacgtcatga tgacttctgg cgcggtaaac cgttaatgcc gcaggtagtg gtggatttag
    39301 gctccggcgg caccggacgt ctgtcgaaac tcctgaccgg ggaatgcgac gttctggcct
    39361 ggcctgctgc cagccagcta tccattttgc gtgacgaccc gcgcttgcgt ttaacgctgc
    39421 gtcctgggat gaacgtcgcc tatctggcat ttaacaccgc caaaccgccg ctaaataatc
    39481 ccgctgtccg ccatgcactg gcactggcga ttaataacca gcgcctgatg caatccatct
    39541 attatggtac ggctgaaacg gcggcctcta ttttaccgcg cgcctcgtgg gcctatgaca
    39601 acgaggctaa aattactgaa tacaatccgg cgaaatcgcg cgaacagttg aaggcgttgg
    39661 ggctggaaaa cttaacgctg aaactgtggg tgcccacacg ttcgcaggcg tggaacccca
    39721 gtccactgaa aactgccgaa ctgattcagg cggatatggc gcaggttggc gtaaaagtgg
    39781 tgattgtgcc ggtagaaggt cgctttcagg aggcgcggtt gatggatatg agccatgatc
    39841 tgacgttatc cggttgggcg acggacagta acgacccgga cagtttcttc cgtccgttac
    39901 tgagctgcgc ggcaattcat tcacagacca acctcgccca ctggtgcgat ccgaaattcg
    39961 acagcgtgtt gcgtaaggcg ctctcctcgc agcagctggc agcgcgtatt gaagcctatg
    40021 acgaagcgca gagtattctg gcgcaggaat tacctattct gccgctggcg tcgtcattgc
    40081 gtttgcaggc ctatcggtac gatatcaaag gtctggtact tagcccgttt ggtaacgcct
    40141 cctttgctgg ggtgtatcgc gagaaacagg atgaggtgaa aaaaccatga ttatcttcac
    40201 cttacgccgc attttgttat tgattgtcac cttgttcctg ctgaccttcg ttggcttcag
    40261 tttgagctat ttcactccac acgcgccgtt acaaggcgcg tcactgtgga atgcctgggt
    40321 gttctggttt aacggcctga tccactggga ttttggtgtt tccagcatta acggtcaacc
    40381 gattgccgaa cagttaaaag aggtcttccc tgcgacgatg gaactgtgca tcctcgcctt
    40441 cggttttgcg ctgattgttg gcatccccgt ggggatgatt gccgggatta cgcgccataa
    40501 gtggcaggat aacttgatca acgccatcgc cttgctgggc ttttcaatcc cggtgttctg
    40561 gctggcgctt ctgttgacgc tgttttgttc actcacgcta ggttggttgc ccgtttcagg
    40621 gcgtttcgat ctgctgtacg aagtgaaacc gattaccggg tttgcgttga ttgatgcctg
    40681 gctttcggac tcaccatggc gggatgaaat gatcatgagc gcaatccgcc atatgatatt
    40741 gcccgtgatc accctgtcgg ttgcgccaac aactgaagtg atccgactga tgcgtatcag
    40801 cactatcgaa gtgtatgacc agaactatgt taaagcggcg gctacccgcg gtttgtcgcg
    40861 ctttactatt ttgcgtcgcc acgttctgca taacgcgtta ccgccggtta ttcctcgcct
    40921 gggcttacag ttttccacca tgctgacgct ggcgatgatc accgaaatgg tttttagctg
    40981 gccgggttta gggcgctggt taattaacgc catccgccag caggattacg cagccatttc
    41041 cgccggagtg atggtgtgtg gctcactggt cattattgtt aacgtgattt ctgatatttt
    41101 gggtgccatg gctaaccctc tgaaacataa ggaatggtat gccttacgat agcgtataca
    41161 gcgaaaagcg cccgccgggc acgctgcgta ccgcctggcg caaattttat agtgacgcct
    41221 ctgcgatggt cggcctgtac ggctgcgcgg ggctggctgt actgtgtatt tttggcggct
    41281 ggtttgcgcc ttacggcatc gaccagcaat ttctcggtta ccaattattg ccgccgtcat
    41341 ggtcgcgcta tggcgaagtt tctttcttcc tggggactga cgacctcgga cgcgatgttt
    41401 taagccgttt actgagcgga gctgcgccaa ccgtgggtgg cgcatttgtg gtgacgcttg
    41461 ccgcgacgat ctgtggcctg gtactgggca ccttcgccgg ggcgacgcac ggcctacgct
    41521 cagcggtgct taaccatatt ctggatacct tactggcgat cccttcgctg ctgctggcaa
    41581 ttatcgttgt agcgtttgcc ggaccgagtt tgtcccacgc tatgtttgct gtctggctgg
    41641 cattgctgcc gcgtatggta cgttcgattt acagcatggt gcatgacgaa ctggaaaaag
    41701 agtacgttat cgccgcccgt ctggatggcg catcaacgct gaatattctc tggtttgctg
    41761 tgatgccaaa catcaccgcc gggctggtca ccgagatcac ccgcgcactg tcgatggcaa
    41821 ttctcgatat cgccgcgctg ggctttctcg atctcggcgc acaactcccc tcgcctgaat
    41881 ggggagcgat gctcggtgat gcgctggaac tgatttatgt cgccccgtgg actgtcatgc
    41941 tgccaggtgc ggcaattatg attagcgtgt tgttggttaa cctccttggc gatggcgttc
    42001 gtcgtgcgat tattgcgggg gtggaataat gccattactc gatattcgta acctgaccat
    42061 tgaatttaaa accggtgatg agtgggttaa agccgtcgac cgggtaagta tgaccttaac
    42121 cgaaggtgaa atccgcggtc ttgttggtga atccggttcc ggcaagagtt tgattgcgaa
    42181 agcgatttgt ggggtgaata aagataactg gcgtgttact gctgaccgta tgcgttttga
    42241 tgatatcgat ttgctgcgtc tctccgcacg cgaacggcgc aaactggttg gccataacgt
    42301 gtcgatgatt ttccaggaac cgcagtcgtg tcttgaccct tcagaacgtg tgggtcgcca
    42361 gttgatgcaa aacatcccag cctggaccta taaaggccgt tggtggcagc gttttggctg
    42421 gcgcaaacgc cgtgccattg aactgctgca ccgcgtgggg attaaagatc acaaagatgc
    42481 gatgcgcagt tttccctatg agttgaccga aggtgaatgt cagaaagtga tgatagccat
    42541 tgcactggcg aatcaaccgc gtctgctgat tgctgacgaa ccgaccaact caatggagcc
    42601 aacaacccag gcgcaaatct ttcgcctgct gacgcgtctc aaccaaaaca gcaataccac
    42661 tattttgctt atcagccatg acttacaaat gcttagccaa tgggcggata aaattaacgt
    42721 gctttactgc ggtcaaacag tggaaaccgc gccgagtaag gagttggtga cgatgccaca
    42781 tcatccttat acccaggcgc tgatccgcgc gataccagac ttcggcagcg cgatgccgca
    42841 taaaagtcgc ctcaatacgc tgcccggcgc tatcccactg ctggaacagt taccgattgg
    42901 ttgtcgtctg gggccacgtt gcccgtatgc acaacgagaa tgcattgtga cgccacgttt
    42961 gacgggggcg aaaaatcatc tctatgcctg tcatttcccg ctgaacatgg agaaagagtg
    43021 agatgatcga aacgctgctt gaagtgcgta atttaagtaa aacgttccgc taccggaccg
    43081 gctggtttcg tcgtcagacc gtagaagcgg taaaaccctt gagctttacg ctacgtgaag
    43141 gccagacact ggcgattatt ggcgagaatg gttcgggtaa atccacgctg gcaaaaatgc
    43201 tggcgggaat gatagagcct accagcggcg agttattgat tgacgatcat ccactgcatt
    43261 ttggcgatta ttccttccgc agtcagcgta ttcgcatgat ttttcaggat ccttcgacct
    43321 cgttgaatcc ccgtcaacgt atctcgcaaa ttctggattt tccactgcgc ctgaacaccg
    43381 acctggaacc ggaacagcgt cgcaaacaga ttattgaaac gatgcgtatg gttgggctgc
    43441 taccggatca cgtcagttac tatccgcata tgttggcacc cggacaaaaa cagcgtctgg
    43501 gtctggcgcg cgcgctgata ttgcgcccaa aagtcattat tgccgatgaa gccctcgctt
    43561 cactggatat gtcgatgcgt tcgcagttga ttaatctgat gctggagtta caggaaaaac
    43621 agggcatttc gtatatttat gttacccagc atatcggaat gatgaagcac attagcgacc
    43681 aggtgctggt gatgcatcag ggcgaggttg tcgagcgagg cagcaccgcg gatgtgctgg
    43741 catcaccgct gcatgaactc accaaacggc tgattgccgg gcactttggc gaagcattga
    43801 cagcggatgc gtggcgtaaa gatcgctaat tttctgaatc ctccttccag attattcacc
    43861 tcattctgac aagagattaa atcttgtcag aatgaggtga tggataaaat aaaatcaaat
    43921 gcgcgtgatt taagaagcaa tctcactttg caggaacgaa agctctggcg atatcttcgc
    43981 agccgacgtt ttggtgattt caaatttcgc cgtcaacatc cggtggggag ctacattctc
    44041 gattttgctt gctgctcggc gcgtgtagtc gttgagctgg atggtgggca gcatgatttg
    44101 gcagttgcct atgattccag gcgcactagc tggcttgagt cgcagggctg gaccgtgctg
    44161 cgtttctgga ataacgagat tgattgtaat gaggagacgg tgctggagaa tattctgcag
    44221 gaactgaacc gccggtcacc ctctccctga aagagcgagg gggccgaccg agccgaatag
    44281 ctgttgtggt gaaaatatgg tgacagttct ggagaatatt cggcaaggtc tgaaccgtcc
    44341 cagccatcgc cctgaaaggg ttagggggct gtataagcct gtttgttgct ggggtgacaa
    44401 tatttgcaca atacggtccc ctcgcccctc tggggagagg attagggtgt ggggaaaagc
    44461 gcccaccctg cccgcaccct gctccggtcg gacctggcag ctatagccac tcacagccag
    44521 gttgattata ataaccgttt atctgttcgt actgtttact aaaacgacga atcgcctgat
    44581 tttcaggcac aacaagcatc aacaataagg attaaagcta tgggttttct ttccggtaag
    44641 cgcattctgg taaccggtgt tgccagcaaa ctatccatcg cctacggtat cgctcaggcg
    44701 atgcaccgcg aaggagctga actggcattc acctaccaga acgacaaact gaaaggccgc
    44761 gtagaagaat ttgccgctca attgggttct gacatcgttc tgcagtgcga tgttgcagaa
    44821 gatgccagca tcgacaccat gttcgctgaa ctggggaaag tttggccgaa atttgacggt
    44881 ttcgtacact ctattggttt tgcacctggc gatcagctgg atggtgacta tgttaacgcc
    44941 gttacccgtg aaggcttcaa aattgcccac gacatcagct cctacagctt cgttgcaatg
    45001 gcaaaagctt gccgctccat gctgaatccg ggttctgccc tgctgaccct ttcctacctt
    45061 ggcgctgagc gcgctatccc gaactacaac gttatgggtc tggcaaaagc gtctctggaa
    45121 gcgaacgtgc gctatatggc gaacgcgatg ggtccggaag gtgtgcgtgt taacgccatc
    45181 tctgctggtc cgatccgtac tctggcggcc tccggtatca aagacttccg caaaatgctg
    45241 gctcattgcg aagccgttac cccgattcgc cgtaccgtta ctattgaaga tgtgggtaac
    45301 tccgcggcat tcctgtgctc cgatctctct gccggtatct ccggtgaagt ggtccacgtt
    45361 gacggcggtt tcagcatcgc tgcaatgaac gaactcgaat tgaaataatc attctgttgg
    45421 taaatattgg gcggcgttct gccgcccgtt atctctgtta tacctttctg atatttgtta
    45481 tcgccgatcc gtctttctcc ccttcccgcc ttgcgtcagg ataacgattt cctttacgac
    45541 caaggagcgc ccatggaaca acgccacatc accggcaaaa gccactggta tcatgaaacg
    45601 caatccagta ctgcggagta tgacgttctg cctctggtcc cggaagccgc aaaggtcagc
    45661 gatccctttc tgctcgacgt gatccttgat gaagaaacgc tggctccctt cctttcatgg
    45721 ctggtccctg cgcgcgttct tgcagtggaa ttgttccctg accagcttac cgtgacccgt
    45781 tcacagacct tcaccgctta tgaacgcttg tctacggccc tgacggttgc tcaggtttgc
    45841 ggcgtccagc ggttatgtaa ctactattcg gcgcgactta cgccgctccc cgggcctgat
    45901 tcctccaggg aaagcaatca taggttggca caaatcacgc aatatgcccg ccaactggct
    45961 agctcgcctt ctattatcga caaccgatcg cgccagcatc tgaatgacgt cggtcttact
    46021 gccggggact gtgtgatcat taaccaaatc attggtttta ttggctttca ggcgcggacc
    46081 attgcgacat ttcaggctta tctcgggcac ccggtacgct ggttacccgg tctggaaata
    46141 caaaactacg ccgacgcgtc actgtttgct gatgaatcaa tacgctggcg aagcagctat
    46201 gaggtggaaa aactacctga agagtacaca aaaagttcaa cagcagaact ttgccaactg
    46261 gccgaaacac tctctctcca ccctatttca ctttcccttc tcgaaaggtt gttaaacagt
    46321 acacgggtta atacacagcc ggataataag cttgcggcgt tgttatgcgc gcggataaat
    46381 ggcagtcctg cttgttttgc cgcctgtatg gattcatcaa atgaatataa aaaaatcagc
    46441 ccccttctgc gcaagggcga aaatgaaatt aaccaatggg ctgaccgtca ttctgttgag
    46501 cacgctaccg ttcaggcgat acaatggctg acccgagcac ccgatcgctt tagcgccgcc
    46561 cagttcagcc ctttactcga acacgaaaaa tcatcaacgc agattattaa tctgctggta
    46621 tggagcgggc tgtgtggctg gataaatcgc ttaaaaatcg cgttgggtga gacatattaa
    46681 ccttgccgcg tcagacagat tcgcgtaaaa ctgtcagccg ctctaatggc caccaaaata
    46741 gacaattatg tttcaggaca acccgctgct agcgcagctt aaacagcaac tgcattccca
    46801 gacgccacgc gctgaagggg tggtaaaagc cacagaaaaa ggctttggct tcctggaagt
    46861 cgacgcgcaa aaaagttatt tcattccgcc gccgcagatg aaaaaagtca tgcatggcga
    46921 ccgaattatc gcggtgatcc acagtgaaaa agaacgtgaa tccgcagagc cagaagaact
    46981 ggttgaaccg ttcctgactc gtttcgtggg taaagttcag ggcaaaaatg accgtctggc
    47041 catcgttcct gatcatccac tcttaaaaga cgccattcct tgccgcgcag cccgtggcct
    47101 gaaccacgag tttaaagaag gcgactgggc ggttgccgaa atgcgccgtc atccgctgaa
    47161 aggcgatcgt tctttctatg ctgaactgac acaatacatc acttttggtg acgaccactt
    47221 tgtaccgtgg tgggttaccc ttgcgcgcca taatctggaa aaagaagcac cagacggcgt
    47281 cgctaccgaa atgctcgatg aaggtctggt tcgtgaagat ctgaccgcgc tggattttgt
    47341 caccatcgac agtgccagca cagaagatat ggatgacgcc cttttcgcta aggcgttgcc
    47401 ggatgacaaa cttcagctga ttgtggcgat tgccgatcca accgcgtgga ttgcagaagg
    47461 cagcaagctg gacaaagccg cgaaaattcg cgcattcacc aactatctgc ctggcttcaa
    47521 catccctatg ctgcctcgcg agctttctga cgatctctgc tcactgcgcg ccaatgaagt
    47581 ccgcccggta ctggcatgcc gcatgacgct ctccgctgat ggcaccattg aagataatat
    47641 cgaattcttt gccgccacca tcgaatccaa agcgaagctg gtgtatgacc aggtttctga
    47701 ctggctggaa aataccggtg actggcagcc tgaaagtgaa gcaattgccg aacaagtccg
    47761 tttgctagcg caaatttgcc aacgccgcgg tgagtggcgt cataaccacg cactggtgtt
    47821 taaagatcgc ccggattacc gctttattct cggtgaaaaa ggtgaagtgc tggatatcgt
    47881 cgccgagcct cgtcgcattg ccaaccgtat cgtcgaagaa gcgatgattg ccgctaacat
    47941 ttgtgcggcc cgcgtactgc gcgataagct cggttttggc atctataacg tgcatatggg
    48001 ctttgatccg gcgaatgccg acgcgctggc agcgttgctg aaaacgcacg gtctgcatgt
    48061 cgatgccgaa gaagtgctca cgctggacgg tttctgcaaa ctgcgtcgtg aactggatgc
    48121 gcaaccaact ggtttcctcg acagccgcat tcgtcgcttc cagtcatttg ctgaaattag
    48181 cactgaaccc ggtcctcact ttggcctcgg tctggaagca tacgccacct ggacttcgcc
    48241 gatccgtaaa tatggcgaca tgatcaacca ccgtctgctg aaagcggtta tcaaaggcga
    48301 aactgcgacg cgcccacagg atgaaatcac tgtccaaatg gccgagcgtc gccgtctcaa
    48361 ccggatggca gaacgtgatg ttggtgactg gttatacgca cgcttcctga aagacaaagc
    48421 cgggaccgac acccgtttcg cagcggaaat tgtcgatatc agccgtggcg gcatgcgtgt
    48481 tcgtttggtt gataacggcg ctatcgcctt tattccggca cctttcttac acgctgtgcg
    48541 cgatgaactg gtttgcagcc aggaaaacgg cactgtacaa attaaaggtg aaacggttta
    48601 caaagtgact gacgttattg acgtcactat tgccgaagtc cgcatggaaa cccgcagcat
    48661 tattgcgcgc ccggtcgcgt aatctccttt cacggcccat tcctcatgga tgggccgttt
    48721 atttccccgc tctaccttcg ttatatccag gcagattttt taactgactt tcgtttgaaa
    48781 actggcgttt ttccaaaact ggattacaaa taaatatata aaaaaaacaa tgcgtttagc
    48841 cgccgttaat ttcatgtaag tcatgttgtt ccttttattt aaccgcggac tccgcagtta
    48901 accggaggat atgcatcatg aaaaccgtta gggagtccac aacgttgtac aactttctcg
    48961 gatcgcacaa tccatactgg cggttgacgg aaagcagcga tgttttgcgc ttttctacca
    49021 ccgaaaccac agaacctgat cgtactttgc agttatctgc cgaacaggct gctcgcatca
    49081 gggaaatgac ggtcatcacc tccagcctga tgatgagtct gaccgtcgat gagagcgatc
    49141 tttctgtgca tctggtagga cgaaaaatca ataaacggga atgggctggc aacgcgtctg
    49201 catggcatga cacaccggcg gttgctcgtg atttatcaca cgggctttcc tttgctgagc
    49261 aggtagtttc tgaagcacat tccgcaatag tcattctcga cagccggggg aatattcaac
    49321 gcttcaatcg gttatgtgaa gattacacag ggttgaaaga acacgacgtc attgggcaaa
    49381 gcgtgtttaa actgtttatg agccgtcgtg aagctgcggc atccaggcgc aataaccgtg
    49441 tattttttcg aagcggcaat gcatatgaag tcgaactgtg gataccaaca tgtaaaggcc
    49501 agcggctgtt tctgtttcgc aataaatttg tccacagcgg cagtggcaaa aacgagattt
    49561 ttttaatctg ttccggcacc gacattaccg aagagcgccg cgctcaggag cgactgcgta
    49621 ttctggcaaa taccgacagt atcaccggac tgccgaatcg taacgcaatg caggatttaa
    49681 tcgatcacgc tattaatcat gcagataaca ataaagttgg ggttgtgtat cttgatttgg
    49741 ataatttcaa aaaggtcaac gacgcctatg ggcatttgtt tggtgaccag ttattacgcg
    49801 acgtgtcatt ggctatttta agctgtctcg aacatgacca ggtgttggcg cgtccaggtg
    49861 gcgatgagtt tctggtactg gcatccaaca cctcacaaag cgcgctggaa gcaatggcat
    49921 cacgaatttt gacccgctta cggctcccct ttcgcattgg tttaattgaa gtttatacca
    49981 gctgttcagt aggtattgca ctctctcccg aacatggttc agacagcacg gctattattc
    50041 gtcacgccga cacagcaatg tacacagcga aggaaggcgg acgaggacaa ttttgcgttt
    50101 ttaccccaga aatgaatcaa cgggtatttg aatatctctg gctggatacc aacttgcgta
    50161 aagcactgga aaacgatcag ttggttattc actatcaacc gaaaatcacc tggcgtggcg
    50221 aagtgcgcag tctggaagca ctagtacgtt ggcagtcacc tgaacgtggg ttgattccac
    50281 cgttggactt catttcctac gccgaagagt cagggctaat tgtgccttta ggccgttggg
    50341 tgattctcga tgtcgtacgc caggtggcga agtggcggga taaaggtatt aacctgcgag
    50401 tggcggtaaa tatttctgca cgtcagctcg ccgatcaaac cattttcacc gccctgaaac
    50461 aggttctcca ggaactcaat tttgaatact gccctataga tgttgaactg acagagagtt
    50521 gtctgattga gaatgatgaa ctggcactgt ctgttattca acaatttagc caactaggtg
    50581 cgcaagtgca tctggatgat tttggtaccg gctactcttc actttcgcaa ctggcgcgct
    50641 ttccgatcga tgccatcaaa cttgaccagg tttttgttcg agatattcac aaacaacctg
    50701 tctcgcagtc actggtccgg gcgatcgtcg ctgtggccca ggcattgaat cttcaggtga
    50761 tcgccgaagg tgtagagagt gcaaaggaag atgctttttt aaccaagaac gggatcaatg
    50821 agcggcaagg atttttgttt gccaaaccga tgcccgccgt cgccttcgaa cgctggtata
    50881 aacgctatct gaagcgcgca taagtagatg aatatatata cttagcgcta tatcccgtca
    50941 ttatatatcg tattcctgga tgataattag ccgttgctgt taaacacttc tcttttagcg
    51001 gcaatttttg cattattcat tttccacttt tgctataagg atgtccttga tgtctgaatt
    51061 tgatgcccag cgcgttgccg aacgtattga tattgtgtta gatatccttg tggcaggcga
    51121 ttaccactct gcgatccata atctcgagat acttaaagca gaactcttgc gccaggttgc
    51181 tgaatctacg ccagacatcc cgaaggcacc gtgggagatt taacaatcgt gccttcaggt
    51241 tttcctattt gaggatgccc ggcgcgtcag tattttttta tttagtatta taacgttata
    51301 agaattacag cgatgaattc ccgacaacaa actattctac agatggtcat tgaccagggt
    51361 caggttagcg taaccgatct ggcaaaagcc actggagttt ctgaagttac cattcgccag
    51421 gatctcaaca ccctcgaaaa actgagttac ctccgccgtg cacatggctt tgcagtttcg
    51481 cttgatagtg atgacgtcga aacccgtatg atgagcaact atacgctgaa gcgtgaactc
    51541 gccgagtttg ccgcgtcact ggttcaaccg ggcgaaacca tctttatcga aaatggtagc
    51601 agcaatgccc tgctcgcccg gactctgggc gaacagaaga aaaatgtcac tatcatcaca
    51661 gtcagcagct acattgcgca tttgctgaaa gacgcgcctt gtgaagtcat tttgctcggt
    51721 ggcgtgtacc agaaaaaaag cgaaagtatg gttggccctt tgacacgcca gtgcatccag
    51781 caggtacatt tcagcaaagc atttattggt attgatggct ggcaacctga aactggattc
    51841 accggtcgcg atatgatgcg taccgatgtg gtcaatgccg tgctggaaaa agagtgcgaa
    51901 gcgatagtcc tgactgacag ctcgaaattt ggtgctgtac attcatactc catcggtccc
    51961 gttgagcgat tcaatcgcgt gattaccgat tcgaaaatac gcgccagcga tctgatgcat
    52021 cttgagcaca gtaaactcac cgttcacgtc gttgacattt aaccatttcc cttctctacg
    52081 gatgatttgc agtttggcaa atcatccgct ctaagatgat tcctggttga taattaagac
    52141 tatttacctg ttattaacac tctcaagata taaaattatt atcagcgata taacaggaag
    52201 tcattatcac ctgcgtgata taaccctgcg cgcgagcaga tttcacggaa taatttcacc
    52261 aggcttattc ttagctatta tagttataga gagcttactt ccgtgaatca taaattcagg
    52321 agagagtatt atgtttgtaa cgagcaaaaa aatgaccgcg gctgttctgg caattaccct
    52381 ggcaatgtct ctgagtgcct gttctaactg gtctaaacgg gaccgcaaca ccgcaatcgg
    52441 cgcgggtgca ggggcattag gcggtgcagt actgaccgat ggcagtacgt tgggtacatt
    52501 aggtggtgca gctgtcggtg gtgttattgg tcaccaggtc ggtaaataat cgtaaataaa
    52561 tgtcgattat cgactcgcaa ttataatacg cttgattctg ttcagtacga aataactgaa
    52621 taatacacac agtaaaatat tcgaaagcca cggatatatc cgtggctttt tatgttaacc
    52681 acctgcgagt tttaccttca tccctttcgc ttcaagtagt gattttaata aatcacgctt
    52741 atcgccctgg atttcaataa ctccatcttt aactgctccg ccgcagccgc attttttctt
    52801 cagttccgct gcaagttttg tcagttcggc atcatcgaga tcgacaccgg taatcaggca
    52861 aacgccctta cctttacgtc cactggtctg acgctgaata cgcaccacac cgtcgccttt
    52921 agggcgtaca ggggccgctt tgggctcatc aatacgtccg gtttccgttg agtagaccag
    52981 acggctgttg gaatcactca tcatgcactc cgctgtaaag aggcgttgat cgctttcagc
    53041 gtctgcgctg gatctaccga ttgcgttacc gggcgaccaa tcaccatata atcaacacca
    53101 gccgacaacg cctgttctgg cgtcataatg cggcgctggt caccagcttc actcccctgc
    53161 ggacgaatgc ccggcgtaac cagtttgaac tcctgaccga atacctgttt aaagcgcaca
    53221 gcttcctgag cagaacacac cacaccatca aggccacatt tttgcgtcag tgccgccaga
    53281 cgttctgcat aatctgcagg tgacagtgtc atgccaagat cgaccaggtc gctggcttcc
    53341 atgctggtca acactgtcac agcaatcaaa agcggtgcat ctttgccaaa cggaaccagt
    53401 gcctcacgcg ctgcggtcat catacgcgcc ccaccagagg catgaacatt caccatccac
    53461 acgcctaagt cagctgcagc agcgacagcg tgcgcagcag tgttaggaat atcgtggaat
    53521 ttcaggtcaa gaaagatatc aaaaccacgc tgttgaagtt cgcgcacaaa ctgtggccca
    53581 aacaatgtaa acatctcttt gccgaccttc agacgacaat cgcgtggttc gatcttgtcg
    53641 acaaaggaca gcgcgtcatc acgattatga taatcaaggg caacaaccac aggagaattc
    53701 gtaacagcgc gggaagaaga tgaagcagtt aacgtcatga ccagaccttc ttgatgatgg
    53761 gcaccggaag tggcgcgaaa caggtaaacg gcgagcattc tacccgtgga aataaaaaat
    53821 taacagttgc gatttttccc ctggcaggct ttttctgcgc cgtcgttgcc ggagcacaat
    53881 ggaacatcaa taactagtat gttgtaacta aagtaggatt tttttaaaaa ttacaggcca
    53941 tcaagaccgc gaatcggttt aatggttgac caggcccgac aagacggaca atgccagtag
    54001 agggtgtatg cggtaaaacc acatttctgg cagcgataac gaggcttact acgtaccttt
    54061 tcgccaacca tgtcacgcag caccatcagg ctctctttgg cacgcccttc ttccgcttca
    54121 tttaagtggt aatccattaa cttatggaac acacgcatgg tcggatgacg ctgaagctgg
    54181 cgcgtaatat agacctgtgc ggcctcacta ccgtcgcgcg cttcgatgat atcagcaagc
    54241 atcaattcag catcggcacc ggtgttctct tccaccgcgc gttgcaggaa ttctgcccat
    54301 tcggcagttt tacccaactg ctgatagcag gtttgcaaca tttccagcgt ttcgctgacc
    54361 agttctctgt cctgggatat cacgcgttgc aaactttcga cggctttggc gtattctcct
    54421 ttcgccataa acacgcgtcc catcatgatg gatacgcggg cgctgttttt atctgccgcc
    54481 gccccttttt ttagcaaggt catggcacga tcgagatcgt cgctggccat atgctgcagg
    54541 gctaactcac agtagaaatg ggcaatttcg acgcgctgtt tatctttacc cagcttcacc
    54601 aggcgttcgg caacatcaat tgctttctgc cactcactgg tagcctggta gatttgtagc
    54661 aactgttgca gagcgccaat gcggaagtca gtttcatcgg tcagctgatt gaacatgtct
    54721 tccgcgcggt cgtataaccc ggcggccatg taatcacgcc ctagttgttg aatcgccaac
    54781 agacgctgtt cataggtcag cgaggcgctt tccattaggg tctgatggat gcgaatagcg
    54841 cgatcaactt cgccacgcga acggaacagg tttccgagcg taaggtgggc ttcaacggtg
    54901 cctgtatcct ctttaagcat atcgagaaac aggtctaccg ctttatcctg ttgattacta
    54961 agcaggaagt taacccccgc tacgtaatca cgcgacaagc ggttggcttc atcttgcttg
    55021 ttttgttgcg cacttctgcg gcccatatac cagccatagg cagcggctac aggcaaaagc
    55081 agaaacaaca actccagcat agaaagttat tccttcgccg ctgacgagtg cggcactaca
    55141 gccacgtcag tcgcgggtga aagctggttt tccagtcgct ttattttacg ttcagcgcgc
    55201 gccagggaaa cacgaactcg cagccagaac aggccacaaa tcaaccaacc gatagcaaac
    55261 cccgcagcaa acaataccgc cagcaatgtg gaaatacggt actccccttg cgctaacaga
    55321 taattaaacg tcacctgttg atcgttctgc gcacccaacg tgaccgaaat cacgaagatc
    55381 gctaacacca gtaagaaaat gagtaaatat ttcacattac ttcccgttat gtggttagag
    55441 cgaataaatt atggtcaact taccgcaata gccctttaaa gtaccatttt cgcgccgtct
    55501 gcgaaatggc atccacgcgc attgttgatg atttaagggc taaattcgga aaatcaacca
    55561 gcgttaactt tcttgttctc gttgcgctat ttcgcgattt tcttccgcag gtggtgttaa
    55621 tggcccacaa attcgttgcg caagccacgt tgccaccgcc accagcgccc acgaaatcaa
    55681 cgtagctact accagatcgc gtggccaatg catcccgagc agcaggcggc ttcccatgac
    55741 tcccgttgcc cagaccagca agatagcaat ggttaacgtt cgccgacgcg gccacagcaa
    55801 accaacggcc agcagtgccc aactggcagc aaacatcgtg tgaccggaag gaaaggcaaa
    55861 ccccgtctct ttctgccagt gtgaacgcaa atattgtggg atatttttct cttcagccaa
    55921 ctgttctttc actagatttc cgcgttctgc tcgctttaaa gtgtagaact catcaaccgg
    55981 aatatgatgt gttttttcca gccagataac aaaaggtcgt ggttcctgga ctttgtcttt
    56041 gatccaggat ttaacgcctt gtcccacaag gattgcggcc gccagaatgg caaataatac
    56101 aaaggcagcc ttaatgcgaa aacgcagaca ccagagaaac cagccgaata aaatcaaatg
    56161 tgtaatgacg ccccagggct gggtgacagt ttcagtaacc caaaaagccg cttttagtag
    56221 ccaactttgt tctccaggtt gccaacgcca gccagaaatc catacggcta ctggcatgac
    56281 aagcaatagt gcagctccca ctgcggtacg tctggcaatc gaacgcatgg cctctccttt
    56341 ttgataagtc ccacaatcat aactgaaaac gccagttcca ggaaaaattg acagatttgt
    56401 gccattccgt gaacgatcga cgcgtcgtga ttaggtgaac cccttctcgt tatggcaaaa
    56461 taagccaata cagaaccagc attatctgga gaatttcatg cagcttaaac gtgtggcaga
    56521 agccaaactg ccaaccccat ggggcgattt cctgatggtg ggatttgaag aactggcaac
    56581 cggacacgat catgtcgcgc tagtctatgg cgatatttcc gggcataccc cggtacttgc
    56641 gcgcgtccat tccgaatgtc tgaccggtga cgccctgttc agcttgcgct gcgattgtgg
    56701 cttccagctc gaagcggcat tgacgcaaat tgccgaggaa ggccgtggta ttttgctgta
    56761 tcaccgtcag gaaggtcgta acattggtct gctgaataaa atccgcgctt acgcactgca
    56821 ggatcaaggt tacgataccg tagaggctaa ccaccagtta ggcttcgccg ctgatgagcg
    56881 cgacttcact ctttgcgctg atatgttcaa actccttggc gtcaatgaag tccgcttgtt
    56941 aaccaataac ccgaaaaaag tcgaaattct gaccgaagca gggattaata ttgttgaacg
    57001 cgtaccattg attgtaggtc gtaaccccaa taacgaacat tatctcgata ccaaagccga
    57061 gaaaatgggc catttgctga acaaataacc ctcttgcatt gtgtaattag tttgcttgcc
    57121 ggaagcaaaa taaccggcaa gcaaatactt gttacttcaa catattacga atgacataat
    57181 gcaaaatgcc gtcgttctgg tagtaggtca actccgtcgc ggtgtcgata cgacaacggc
    57241 agggtacgac ctcctggcta ccatccgcgc gcgtaagcgt caccggaacc gtcgcaccgg
    57301 gttgtagatt ttgcagatcg ccaatatcaa tcttctcttc cccggttagt cctaacgttt
    57361 tacgcgttac gccttgcgga aattccagcg gcaggatgcc catgccaatt aaattcgaac
    57421 ggtgaattcg ttcaaacgat tcggcaatca ccacacgaat tccaagcaga cgaggacctt
    57481 ttgccgccca gtcacggctt gagcctgatc catactcttt cccggcaatc accgccagcg
    57541 gcgtttgttc ctgcttatag cgcatcgcag catcataaat agagactacg tcgctgtcag
    57601 gtaaatgccg cgtcatcccc ccttcaacgc caggcaccat ttcattacgg atgcgaatat
    57661 tggcgaaggt gccgcgcatc atcacttcat ggttaccacg ccgcgaaccg taggagttaa
    57721 agtcttttcg ctcaacaccc cgaccttgta gatatcgacc cgctgggctg tcgggcttaa
    57781 tactgcccgc cggagagata tggtcagtgg tgactgaatc ccccagcatt gcgaggatcc
    57841 gcgcaccgtg aatatcttcc actggtgctg gtgttgcctg catttcatca aagaaaggcg
    57901 ataagcgaat ataggttgag tcctcctgcc aaccgtaggt atcggatcgt gtgacgttaa
    57961 tttccttcca ctctgctgtg ccttcaaaaa cttctgcgta ctctttgcgg aacatttctg
    58021 tggagacttg ttctaccgca cgggcaattt cttgtgccga tggccagata tctttcagat
    58081 ataccggatc gcctttacga tcatggccga taggctcaga agccaggttg atattcatat
    58141 ttcccgccag cgcataggca accaccagcg gcggcgaggc cagccagttg gttttaacca
    58201 gcggatggat acggccttca aagttacggt tgccggacag cactgcaccg acggttaaat
    58261 cgcctttttt gattgccgtt tcgataggat cgggcagcgg cccagagtta ccaatacagg
    58321 tggtacaacc gtatcccaca aggttaaacc ccagttcgtc gagatacggt gtcaatttcg
    58381 cttttgccag ataatcagaa acaactttcg agcctggtgc cagcgacgct ttgacccacg
    58441 gttgccgctt gaggccaaga gttacggctt ttttcgccag caagcctgca gccatcagca
    58501 cacttgggtt agaggtgttg gtgcacgagg ttatcgcagc aatgaccaca gcgccatcag
    58561 gtaactgata ctgatgtccg ttcataacat aatcgaccgg ctggcgatct ttatgcgtgg
    58621 cattcacttc cagttcgtta ctggcggcaa atgcttttgg tacatcgggc agtgcaacgc
    58681 gatcctgtgg gcgttttggc cctgccaggc tcgcttcaac gtcattcata tccagttcta
    58741 acgtactggt aaaaatcggt tcatcgcccg ggttacgcca catgccctgc gctttggcat
    58801 atttttcgac caactcaacc tgatcttcgc tgcgcccgct taaacgcatg taatcgaggg
    58861 ttacagcatc gattgggaag aagccacagg tggcaccata ttctggcgac atattggcaa
    58921 tggtggcgcg atccgccagc ggtagtgaat ccagaccatc accataaaat tcgacgaatt
    58981 tccccaccac gccatgtttg cgcagcattt gggtaacagt gagaaccagg tctgtggcgg
    59041 taataccttc acgtaattta ccggtaagtt taaagcccac tacgtccggg ataagcatgg
    59101 aaaccggctg gcctaacatt gcggcttctg cttcgatccc acccacgccc caccccagca
    59161 cgccaaggcc gttgatcata gtggtgtgcg agtcagtacc aacgagtgta tccggataag
    59221 caatccattc accgtcctgc aattcactcc acactgcttt gccgagatat tcgaggttaa
    59281 cctgatggca aatgcctgtg cctggcggca cgacgctaaa ccgactgaac gcttgctttc
    59341 cccatttcag gaacacataa cgttcgtggt tgcgctccat ttccaggcgt acgttttctt
    59401 caaatgcctc atcatcacca aaacgatcga cggtcaccga gtggtcaatg accaggtcga
    59461 ccggtgagag cgggttaacc tttgcagtat cgccgccgag gcgtttaacc gcttcgcgca
    59521 ttgccgccag atcaacaacg gcaggtacgc cggtaaagtc ctgcatcagc acccttgccg
    59581 ggcggtaggc aatttcacgg tcagcatggg catttttcag ccatcctgcc agcgcgtgga
    59641 tatcctcttc ggtaaccgag ttaccatcct gccagcgcag caggttttcg agcaaaactt
    59701 tgagtgactt gggcagacgg gtgatatcgc ccagtgattt agcagcaagc ggcaggctgt
    59761 agtagtggta agttttatct ttggcctgca acgtgtcctt actggcttct cgtagggttg
    59821 acgacatagc tcctccttaa tgacagggtt gcgaagccct gattctcttc agggtgaata
    59881 ttaaagataa cacaaacatc gcgtaacgat ttgataacaa cccaaattga taaaagagga
    59941 gaaaccttgt ggcaaagcaa atgacaaccc cgccgcagcg gggtcaagga tcagtgagta
    60001 atgatccaga ggagttcggc ccagaagagc atcgacagag aaaacgcgcc catccaggac
    60061 caatatttca tatttgtgtt gatcataggc tacaccctta acggttatta ttttgtgttg
    60121 agataactca agctgttatt gctgcggtgt attaaaagcc ctttaattca ttaaaaatgg
    60181 gtaataagaa tgatgataat tattgtttcg gctgatcatc ttcagcaaac agttctataa
    60241 aggcttgctg ctgcgatgtt agttgccagt cgtctggaat aacgacggaa cattcccgtt
    60301 tcgtttctgt ttcattgtca ctatgctggc ataatggtga cgactccagt tgctcctgac
    60361 cgaccatagt tatccccaca ctttccaaat cagcagtgcg acaaccaccc agaaaagtgc
    60421 agaaccaaga aaaaccgcca gccaggcttt acgttttaat tcaggatcgc ggcggggttc
    60481 ctgatttcca gaaggcattg ctaacctcat ataatcgcca tcacttatca gcaagacgtt
    60541 gaacgattgg tgtaattaat catacgatga gacaaatcct aaagaaactt tagtcaaaaa
    60601 tccagcgaat ttacgaatcg tctccagtga ataattcaat cttttgacct gaaatagata
    60661 tttgaaaact ggagtttgcg aggcgggtaa ttagacacta ctttacaggt aatttaccct
    60721 ataaatatga gggataaaa
//
LOCUS       DAPGUL010000014        59007 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.014, whole genome shotgun sequence.
ACCESSION   DAPGUL010000014 DAPGUL010000000
VERSION     DAPGUL010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 59007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59007
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.014"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            151..822
                     /locus_tag="RHX21_001016"
     CDS             151..822
                     /locus_tag="RHX21_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016241930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HDV1986240.1"
                     /translation="MDKVLDSALLSSANKRKGILAIGAHPDDIELGCGASLARLAQKG
                     IYIAAVVMTTGNSGTDGIIDRHEESRNALKILGCHQTIHLNFADTRAHLQLNDMISAL
                     EDIIKNQIPSDVEIMRVYTMHDADRHQDHLAVYQASMVACRTIPQILGYETPSTWLSF
                     MPQVFESVKEEYFTVKLAALKKHKSQERRDYMRHDRLRAVAQFRGQQVNSDLGEGFVI
                     HKMIL"
     gene            832..2028
                     /locus_tag="RHX21_001017"
     CDS             832..2028
                     /locus_tag="RHX21_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDV1986241.1"
                     /translation="MKTWIFICMSIAMLLWFLSTLRRKPSQKKGCIDAIIPAYNEGPC
                     LAQSLDNLLRNPYFCRVICVNDGSTDNTEAVMAEVKRKWGDRFVAVTQKNTGKGGALM
                     NGLNYATCDQVFLSDADTYVPPDQDGMGYMLAEIERGADAVGGIPSTALKGAGLLPHI
                     RATVKLPMIVMKRTLQQLLGGAPFIISGACGMFRTDVLRKFGFSDRTKVEDLDLTWTL
                     VANGYRIRQANRCIVYPQECNSPREEWRRWRRWIVGYAVCMRLHKRLLFSRFGIFSIF
                     PMLLVVIYGVGIYLTTWFNEFITTGPHGVVLAMFPLIWIGVVCVIGAFSAWFHRCWLL
                     VPLAPLSVVYVLLAYAIWIIYGLIAFFTGREPQRDKPTRYSALVEASTAYSQPSVTGT
                     EKLSEA"
     gene            2006..2587
                     /locus_tag="RHX21_001018"
     CDS             2006..2587
                     /locus_tag="RHX21_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001308433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDV1986242.1"
                     /translation="MKNYLKLNVKEKNIQIADQVIIDETAGEVVIGANTRICHGAVIQ
                     GPVVIGANCLIGNYAFIRPGTIISNGVKIGFATEIKNAVIEAEATIGPQCFIADSVVA
                     NQAYLGAQVRTSNHRLDEQPVSVRTPEGIIATGCDKLGCYIGQRSRLGVQVIILPGRI
                     ISPNTQLGPRVIVERNLPAGTYSLRQELIRTGD"
     gene            2589..3362
                     /locus_tag="RHX21_001019"
     CDS             2589..3362
                     /locus_tag="RHX21_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiO family outer membrane beta-barrel protein"
                     /protein_id="HDV1986243.1"
                     /translation="MIKRTLLAAAIFSALPAYAGLTSITAGYDFTDYSGDHGNRNLAY
                     AELVAKVENATLLFNLSQGRRDYETENFNATRGQGAVWYKWNNWLTTRTGIAFADNTP
                     VFARQDFRQDINLALLPKTLFTTGYRYTKYYDDVEVDAWQGGVSLYTGPVITSYRYTH
                     YDSSDAGGSYSNMISVRLNDPRGTGYTQLWLSRGTGAYTYDWTPETRYGSMKSVSLQR
                     IQPLTEQLNLGLTAGKVWYDTPTDDYNGLQLAAHLTWKF"
     gene            3547..3822
                     /gene="frmR"
                     /locus_tag="RHX21_001020"
     CDS             3547..3822
                     /gene="frmR"
                     /locus_tag="RHX21_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414891.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formaldehyde-responsive transcriptional
                     repressor FrmR"
                     /protein_id="HDV1986244.1"
                     /translation="MPSTPEEKKKVLTRVRRIRGQIDALERSLEGDAECRAILQQIAA
                     VRGAANGLMAEVLESHIRETFDRNDCYSREVSQSVDDTIELVRAYLK"
     gene            3857..4966
                     /gene="frmA"
                     /locus_tag="RHX21_001021"
     CDS             3857..4966
                     /gene="frmA"
                     /locus_tag="RHX21_001021"
                     /EC_number="1.1.1.284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-(hydroxymethyl)glutathione dehydrogenase"
                     /protein_id="HDV1986245.1"
                     /translation="MKSRAAVAFAPGKPLEIVEIDVAPPKKGEVLIKVTHTGVCHTDA
                     FTLSGDDPEGVFPVVLGHEGAGVVVEVGEGVTSVKPGDHVIPLYTAECGECEFCRSGK
                     TNLCVAVRETQGKGLMPDGTTRFSYNGQPLYHYMGCSTFSEYTVVAEVSLAKINPEAN
                     HEHVCLLGCGVTTGIGAVHNTAKVQPGDSVAVFGLGAIGLAVVQGARQAKAGRIIAID
                     TNPKKFDLARRFGATDCINPNDYDKPIKDVLLDINKWGIDHTFECIGNVNVMRAALES
                     AHRGWGQSVIIGVAGSGQEISTRPFQLVTGRVWKGSAFGGVKGRSQLPGMVEDAMKGD
                     IDLEPFVTHTMSLDEINDAFDLMHEGKSIRTVIRY"
     gene            5059..5892
                     /gene="fghA"
                     /locus_tag="RHX21_001022"
     CDS             5059..5892
                     /gene="fghA"
                     /locus_tag="RHX21_001022"
                     /EC_number="3.1.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="HDV1986246.1"
                     /translation="MELIEKHASFGGWQNVYRHYSQSLKCEMNVGVYLPPKAANEKLP
                     VLYWLSGLTCNEQNFITKSGMQRYAAEHNIIVVAPDTSPRGSHVADADRYDLGQGAGF
                     YLNATQAPWNEHYKMYDYIRNELPDLVMQHFPATTRKSISGHSMGGLGALVLALRNPD
                     EYVSVSAFSPIVSPSQVPWGQQAFAAYLGENKDAWLDYDPVSLISQGQRVAEIMVDQG
                     LSDDFYAEQLRTPNLEKICQEMNIKTLIRYHEGYDHSYYFVSSFIGEHIAYHANKLNM
                     R"
     gene            complement(6017..6556)
                     /locus_tag="RHX21_001023"
     CDS             complement(6017..6556)
                     /locus_tag="RHX21_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414888.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2058 domain-containing protein"
                     /protein_id="HDV1986247.1"
                     /translation="MAKLTLQEQLLKAGLVTSKKAAKVERTAKKSRVQAREARAAVEE
                     NKKAQLERDKQLSEQQKQAALAKEYKAQVKQLIEMNRITIANGDIGFNFTDGNLIKKI
                     FVDKLTQAQLINGRLAIARLLVDNNSEGEYAIIPASVADKIAQRDASSIVLHSALSAE
                     EQDEDDPYADFKVPDDLMW"
     gene            complement(6658..7869)
                     /gene="mhpT"
                     /locus_tag="RHX21_001024"
     CDS             complement(6658..7869)
                     /gene="mhpT"
                     /locus_tag="RHX21_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308435.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-(3-hydroxy-phenyl)propionate transporter MhpT"
                     /protein_id="HDV1986248.1"
                     /translation="MSTRTPSSSSSRLMLTIGLCFLVALMEGLDLQAAGIAAGGIAQA
                     FALDKMQMGWIFSAGILGLLPGALVGGMLADRYGRKRILIGSVALFGLFSLATAIAWD
                     FPSLVFARLMTGVGLGAALPNLIALTSEAAGPRFRGTAVSLMYCGVPIGAALAATLGF
                     AGANLAWQTVFWVGGVVPLILVPLLMRWLPESAVFAGEKQAAPPLRALFAPETATATL
                     LLWLCYFFTLLVVYMLINWLPLLLVEQGFQPSQAAGVMFALQMGAASGTLMLGALMDK
                     LRPVTMSLLIYSGMLASLLALGTVSSFNGMLLAGFVAGLFATGGQSVLYALAPLFYSS
                     QIRATGVGTAVAVGRLGAMSGPLLAGKMLALGTGTVGVMAASAPGILVAGLAVFILMS
                     RRSRMQPCADA"
     gene            complement(8045..9058)
                     /gene="dmpG"
                     /locus_tag="RHX21_001025"
     CDS             complement(8045..9058)
                     /gene="dmpG"
                     /locus_tag="RHX21_001025"
                     /EC_number="4.1.3.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-2-oxovalerate aldolase"
                     /protein_id="HDV1986249.1"
                     /translation="MNGKKLYISDVTLRDGMHAIRHQYSLENVRQIAKALDDARVDSI
                     EVAHGDGLQGSSFNYGFGAHSDLEWIEAAADVVKHAKIATLLLPGIGTIHDLKNAWQA
                     GARVVRVATHCTEADVSAQHIQYARELGMDTVGFLMMSHMTTPENLAKQAKLMEGYGA
                     TCIYVVDSGGAMNMSDIRDRFRALKAELKPETQTGMHAHHNLSLGVANSIAAVEEGCD
                     RIDASLAGMGAGAGNAPLEVFIAAADKLGWQHGTDLYALMDAADDLVRPLQDRPVRVD
                     RETLALGYAGVYSSFLRHCETAAARYGLSAVDILVELGKRRMVGGQEDMIVDVALDLR
                     NNK"
     gene            complement(9055..10005)
                     /gene="mhpF"
                     /locus_tag="RHX21_001026"
     CDS             complement(9055..10005)
                     /gene="mhpF"
                     /locus_tag="RHX21_001026"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase"
                     /protein_id="HDV1986250.1"
                     /translation="MSKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGL
                     ARARRMGVATTHEGVIGLMNMPEFADIDIVFDATSAGAHVKNDAALREAKPDIRLIDL
                     TPAAIGPYCVPVVNLEANVDQLNVNMVTCGGQATIPMVAAVSRVARVHYAEIIASIAS
                     KSAGPGTRANIDEFTETTSRAIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEAS
                     QDDIEASINEMAEAVQAYVPGYRLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEV
                     EGAAHYLPAYAGNLDIMTSSALATAEKMAQSLARKAGEAA"
     gene            complement(10002..10811)
                     /gene="mhpD"
                     /locus_tag="RHX21_001027"
     CDS             complement(10002..10811)
                     /gene="mhpD"
                     /locus_tag="RHX21_001027"
                     /EC_number="4.2.1.80"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308432.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-4-pentenoate hydratase"
                     /protein_id="HDV1986251.1"
                     /translation="MTKHTLEQLAADLRRAAEQGEAIAPLRDLIGIDNAEAAYAIQHI
                     NVQYDVAQGRRVVGRKVGLTHPKVQQQLGVDQPDFGTLFADMCYGDNEIIPFSRVLQP
                     RIEAEIALVLNRDLPATDITFDELYNAIEWVLPALEVVGSRIRDWSIQFVDTVADNAS
                     CGVYVIGGPAQRPAGLDLKNCAMKMTRNNEEVSSGRGSECLGHPLNAAVWLARKMASL
                     GEPLRAGDIILTGALGPMVAVNAGDRFEAHIEGIGSVAATFSSAAPKGSLS"
     gene            complement(10821..11687)
                     /gene="mhpC"
                     /locus_tag="RHX21_001028"
     CDS             complement(10821..11687)
                     /gene="mhpC"
                     /locus_tag="RHX21_001028"
                     /EC_number="3.7.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414883.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-6-oxonona-2,4-dienedioate hydrolase"
                     /protein_id="HDV1986252.1"
                     /translation="MSYQPQTEAATSRFLNVEEAGKTLRIHFNDCGQGDETVVLLHGS
                     GPGATGWANFSRNIDPLVEAGYRVILLDCPGWGKSDSIVNSGSRSDLNARILKSVVDQ
                     LDIAKIHLLGNSMGGHSSVAFTLNWPERVGKLVLMGGGTGGMSLFTPMPTEGIKRLNQ
                     LYRQPTIENLKLMMDIFVFDTSDLTDALFEARLNNMLSRRDHLENFVKSLEANPKQFP
                     DFGPRLAEIKAQTLIVWGRNDRFVPMDAGLRLLSGIAGSELHIFRDCGHWAQWEHADA
                     FNQLVLNFLARP"
     gene            complement(11705..12649)
                     /gene="mhpB"
                     /locus_tag="RHX21_001029"
     CDS             complement(11705..12649)
                     /gene="mhpB"
                     /locus_tag="RHX21_001029"
                     /EC_number="1.13.11.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-carboxyethylcatechol 2,3-dioxygenase"
                     /protein_id="HDV1986253.1"
                     /translation="MHAYLHCLSHSPLVGYVDPAQEVLDEVNGVIASARERIAAFSPE
                     LVVLFAPDHYNGFFYDVMPPFCLGVGATAIGDFGSAAGELPVPVELAEACAHAVMKSG
                     IDLAVSYCMQVDHGFAQPLEFLLGGLDKVPVLPVFINGVATPLPGFQRTRMLGEAIGR
                     FTSTLNKRVLFLGSGGLSHQPPVPELAKADAHMRDRLLGSGKDLPASERELRQQRVIS
                     AAEKFVEDQRTLHPLNPIWDNQFMTLLEQGRIQELDAVSNEELSAIAGKSTHEIKTWV
                     AAFAAISAFGNWRSEGRYYRPIPEWIAGFGSLSARTEN"
     gene            complement(12651..14315)
                     /locus_tag="RHX21_001030"
     CDS             complement(12651..14315)
                     /locus_tag="RHX21_001030"
                     /EC_number="1.14.13.127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid
                     hydroxylase"
                     /protein_id="HDV1986254.1"
                     /translation="MAIQHPDIQPAVNHSVQVAIAGAGPVGLMMANYLGQMGIDVLVV
                     EKLDKLIDYPRAIGIDDEALRTMQSVGLVENVLPHTTPWHAMRFLTPKGRCFADIQPM
                     TDEFGWPRRNAFIQPQVDAVMLEGLSRFPNVRCLFARELEAFSQQNDEVTLHLKTAEG
                     QREIVKAQWLVACDGGASFVRRTLNVPFEGKTAPNQWIVVDIANDPLSTPHIYLCCDP
                     VRPYVSAALPHAVRRFEFMVMPGETEEQLREPQNMRKLLSKVLPNPDNVELIRQRVYT
                     HNARLAQRFRIDRVLLAGDAAHIMPVWQGQGYNSGMRDAFNLAWKLALVIQGKARDAL
                     LDTYQQERRDHAKAMIDLSVTAGNVLAPPKRWQGTLRDGVSWLLNYLPPVKRYFLEMR
                     FKPMPQYYGGALVREGEAKHSPVGKMFIQPKVTLENGDVTLLDNAIGANFAVIGWGCN
                     PLWGMSDEQIQQWRALGTRFIQVVPEVQIHTAQDNHDGVLRVGDTQGRLRSWFAQHNA
                     SLVVMRPDRFVAATAIPQTLGNTLNKLASVMTLTRPDADVSVEKVA"
     gene            14393..15340
                     /gene="mhpR"
                     /locus_tag="RHX21_001031"
     CDS             14393..15340
                     /gene="mhpR"
                     /locus_tag="RHX21_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator MhpR"
                     /protein_id="HDV1986255.1"
                     /translation="MIFYCALSIGRVFSATIKTCPNVHQVHNVVLTIEMSINMQNNEQ
                     TEYKTVRGLTRGLMLLNMLNKLDGGASVGLLAELSGLHRTTVRRLLETLQEEGYVRRS
                     PSDDSFRLTIKVRQLSEGFRDEQWISALAAPLLGDLLREVVWPTDVSTLDVDAMVVRE
                     TTHRFSRLSFHRAMVGRRLPLLKTASGLTWLAFCPEQERKELIEMLAARPGDDYQLAR
                     EPLKLQAILARARKEGYGQNYRGWDQEEKIASIAVPLRSEQRVIGCLNLVYMASAMTI
                     EQAAEKHLPALQRVAKQIEEGVESQAILVAGRRSGVHLR"
     gene            15417..16499
                     /gene="lacI"
                     /locus_tag="RHX21_001032"
     CDS             15417..16499
                     /gene="lacI"
                     /locus_tag="RHX21_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414879.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor LacI"
                     /protein_id="HDV1986256.1"
                     /translation="MKPVTLYDVAEYAGVSYQTVSRVVNQASHVSAKTREKVEAAMAE
                     LNYIPNRVAQQLAGKQSLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERS
                     GVEACKAAVHNLLAQRVSGLIINYPLDDQDAIAVEAACTNVPALFLDVSDQTPINSII
                     FSHEDGTRLGVEHLVALGHQQIALLAGPLSSVSARLRLAGWHKYLTRNQIQPIAEREG
                     DWSAMSGFQQTMQMLNEGIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGYDDT
                     EDSSCYIPPLTTIKQDFRLLGQTSVDRLLQLSQGQAVKGNQLLPVSLVKRKTTLAPNT
                     QTASPRALADSLMQLARQVSRLESGQ"
     gene            16622..19696
                     /gene="lacZ"
                     /locus_tag="RHX21_001033"
     CDS             16622..19696
                     /gene="lacZ"
                     /locus_tag="RHX21_001033"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HDV1986257.1"
                     /translation="MTMITDSLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEAR
                     TDRPSQQLRSLNGEWRFAWFPAPEAVPESWLECDLPEADTVVVPSNWQMHGYDAPIYT
                     NVTYPITVNPPFVPTENPTGCYSLTFNVDESWLQEGQTRIIFDGVNSAFHLWCNGRWV
                     GYGQDSRLPSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHK
                     PTTQISDFHVATHFNDDFSRAVLEAEVQMYGELRDELRVTVSLWQGETQVASGTAPFG
                     GEIIDERGGYADRVTLRLNVENPALWSAEIPNLYRAVVELHTADGTLIEAEACDVGFR
                     EVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSH
                     YPNHPLWYTLCDRYGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRN
                     HPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQYEGGGADTTATDIICPMYARVD
                     EDQPFPAVPKWSIKKWLSLPGELRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGG
                     FVWDWVDQSLIKYDENGNPWLAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKYQ
                     QQFFQFRLSGQTIEVTSEYLFRHSDNELLHWMVALDGKPLASGEVPLDVAPQGKQLIE
                     LPGLPQPESAGQLWLTVHVVQPNATAWSEAGHISAWQQWRLAENLSVTLPAASHAIPH
                     LTTSEMDFCIELGNKRWQFNRQSGFLSQMWIGDKKQLLTPLRDQFTRAPLDNDIGVSE
                     ATRIDPNAWVERWKVAGHYQAEAALLQCSADTLADAVLITTAHAWQHQGKTLFISRKT
                     YRIDGSGQMAITVDVEVASDTPHPARIGLTCQLAQVAERVNWLGLGPQENYPDRLTAA
                     CFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNISRYSQQQLMETS
                     HRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK"
     gene            19748..21001
                     /gene="lacY"
                     /locus_tag="RHX21_001034"
     CDS             19748..21001
                     /gene="lacY"
                     /locus_tag="RHX21_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactose permease"
                     /protein_id="HDV1986258.1"
                     /translation="MYYLKNTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSD
                     TGIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYN
                     ILVGSIVGGIYLGFCFNAGAPAVEAFIEKVSRRSNFEFGRARMFGCVGWALCASIVGI
                     MFTINNQFVFWLGSGCALILAVLLFFAKTDAPSSATVANAVGANHSAFSLKLALELFR
                     QPKLWFLSLYVIGVSCTYDVFDQQFANFFTSFFATGEQGTRVFGYVTTMGELLNASIM
                     FFAPLIINRIGGKNALLLAGTIMSVRIIGSSFATSALEVVILKTLHMFEVPFLLVGCF
                     KYITSQFEVRFSATIYLVCFCFFKQLAMIFMSVLAGNMYESIGFQGAYLVLGLVALGF
                     TLISVFTLSGPGPLSLLRRQVNEVA"
     gene            21067..21678
                     /gene="lacA"
                     /locus_tag="RHX21_001035"
     CDS             21067..21678
                     /gene="lacA"
                     /locus_tag="RHX21_001035"
                     /EC_number="2.3.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactoside O-acetyltransferase"
                     /protein_id="HDV1986259.1"
                     /translation="MNMSMTERIKAGKLFTDMCEGLPEKRLRGKTLMYEFNHSHPSEV
                     EKRESLIKEMFATVGENAWIEPPVYFSYGSNIHIGRNFYANFNLTIVDDYTVTIGDNV
                     LIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNNVWIGSHVVINPGVTIGDNSVIGA
                     GSVVIKDIPPNVVAAGVPCRVIREINDRDKQYYFKDYKVESSV"
     gene            complement(21781..22962)
                     /gene="cynX"
                     /locus_tag="RHX21_001036"
     CDS             complement(21781..22962)
                     /gene="cynX"
                     /locus_tag="RHX21_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308421.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyanate transporter CynX"
                     /protein_id="HDV1986260.1"
                     /translation="MRNHQKTFTMLLVLVLIGLNMRPLLTSVGPLLPQLRQASGMSFS
                     VAALLTALPVVTMGGLALAGSWLHQHVSERRSVAISLLLIAVGALMRELYPQSVLLLS
                     SALLGGVGIGIIQAVMPSVIKRRFQQRTPQVMGLWSAALMGGGGLGAAITPWLVQHSE
                     SWYQTLAWWALPAVVALFAWWWQSAREVASSHKTTTTPVRVVFTPRAWTLGVYFGLIN
                     GGYASLIAWLPAFYIEIGASAQYSGSLLALMTLGQAAGALLMPAMARHQDRRKLLMLA
                     LVLQLVGFCGFIWLPLQLPVLWAMVCGLGLGGAFPLCLLLALDHSVQPAIAGKLVAFM
                     QGIGFIIAGLAPWFSGVLRSISGNYLMDWAFHALCVVGLMIITLRFAPARFPQLWVKE
                     A"
     gene            complement(22968..23438)
                     /gene="cynS"
                     /locus_tag="RHX21_001037"
     CDS             complement(22968..23438)
                     /gene="cynS"
                     /locus_tag="RHX21_001037"
                     /EC_number="4.2.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyanase"
                     /protein_id="HDV1986261.1"
                     /translation="MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVT
                     AALLGQQALPADAARLVGAKLDLDEDAILLLQMIPLRGCIDDRIPTDPTMYRFYEMLQ
                     VYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF"
     gene            complement(23469..24128)
                     /gene="cynT"
                     /locus_tag="RHX21_001038"
     CDS             complement(23469..24128)
                     /gene="cynT"
                     /locus_tag="RHX21_001038"
                     /EC_number="4.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase CynT"
                     /protein_id="HDV1986262.1"
                     /translation="MKEIIDGFLKFQREAFPKREALFKQLATQQSPRTLFISCSDSRL
                     VPELVTQREPGDLFVIRNAGNIVPSYGPEPGGVSASVEYAVAALRVSDIVICGHSNCG
                     AMTAIASCQCMDHMPAVSHWLRYADSARVVNEARPHSDLPSKAAAMVRENVIAQLANL
                     QTHPSVRLALEEGRIALHGWVYDIESGSIAAFDGATRQFVPLAANPRVCAIPLRQPTA
                     A"
     gene            24238..25137
                     /gene="cynR"
                     /locus_tag="RHX21_001039"
     CDS             24238..25137
                     /gene="cynR"
                     /locus_tag="RHX21_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator CynR"
                     /protein_id="HDV1986263.1"
                     /translation="MLSRHINYFLAVAEHGSFTRAASALHVSQPALSQQIRQLEESLG
                     VPLFDRSGRTIRLTDAGEVWRQYASRALQELGAGKRAIHDVADLTRGSLRIAVTPTFT
                     SYFIGPLMADFYARYPGITLQLQEMSQEKIEDLLCRDELDVGIAFAPVHSPELEAIPL
                     LTESLALVVAKHHPLAACEQVALSRLHDEKLVLLSAEFATREQIDHYCEKAGLHPQVV
                     IEANSISAVLELIRRTSLSTLLPAAIATQHDGLKAISLAPPLLERTAVLLRRKNSWQT
                     AAAKAFLHMALEECADVGENESR"
     gene            complement(25177..26460)
                     /gene="codA"
                     /locus_tag="RHX21_001040"
     CDS             complement(25177..26460)
                     /gene="codA"
                     /locus_tag="RHX21_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine/isoguanine deaminase"
                     /protein_id="HDV1986264.1"
                     /translation="MSNNALQTIINARLPGKEGLWQIHLQDGKISAIDAQSGVMPITE
                     NSLDAEQGLVIPPFVEPHIHLDTTQTAGQPNWNQSGTLFEGIERWAERKALLTHDDVK
                     QRAWQTLKWQIANGIQHVRTHVDVSDATLTALKAMLEVKQEVAPWIDLQIVAFPQEGI
                     LSYPNGEALLEEALRLGADVVGAIPHFEFTREYGVESLHKTFALAQKYDRLIDVHCDE
                     IDDEQSRFVETVAALAHREGMGARVTASHTTAMHSYNGAYTSRLFRLLKMSGINFVAN
                     PLVNIHLQGRFDTYPKRRGITRVKEMLESGINVCFGHDDVFDPWYPLGTANMLQVLHM
                     GLHVCQLMGYGQINDGLNLITHHSARTLNLQDYGIAAGNSANLIILPAENGFDALRRQ
                     VPVRYSVRGGKVIASTQPAQTTVYLEQPEAIDYKR"
     gene            complement(26450..27709)
                     /gene="codB"
                     /locus_tag="RHX21_001041"
     CDS             complement(26450..27709)
                     /gene="codB"
                     /locus_tag="RHX21_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HDV1986265.1"
                     /translation="MSQDNNFSQGPVPQSARKGVLALTFVMLGLTFFSASMWTGGTLG
                     TGLSYHDFFLAVLIGNLLLGIYTSFLGYIGAKTGLTTHLLARFSFGVKGSWLPSLLLG
                     GTQVGWFGVGVAMFAIPVGKATGLDINLLIAVSGLLMTVTVFFGISALTVLSVIAVPA
                     IACLGGYSVWLAVNGMGGLDALKAVVPAQPLDFNVALALVVGSFISAGTLTADFVRFG
                     RNAKLAVLVAMVAFFLGNSLMFIFGAAGAAALGMADISDVMIAQGLLLPAIVVLGLNI
                     WTTNDNALYASGLGFANITGMSSKTLSVINGIIGTVCALWLYNNFVGWLTFLSAAIPP
                     VGGVIIADYLMNRRRYEHFATTRMMSVNWVAILAVALGIAAGHWLPGIVPVNAVLGGA
                     LSYLILNPILNRKTTAAMTHVEVNSVE"
     gene            complement(27946..29832)
                     /gene="prpE"
                     /locus_tag="RHX21_001042"
     CDS             complement(27946..29832)
                     /gene="prpE"
                     /locus_tag="RHX21_001042"
                     /EC_number="6.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate--CoA ligase"
                     /protein_id="HDV1986266.1"
                     /translation="MSFSEFYQRSINEPEQFWAEQARRIDWQTPFTQTLDHSNPPFAR
                     WFCEGRTNLCHNAIDRWLEKQPEALALIAVSSETEEERTFTFRQLHDEVNAVASMLRS
                     LGVQRGDRVLVYMPMIAEAHITLLACARIGAIHSVVFGGFASHSVAARIDDAKPVLIV
                     SADAGARGGKIIPYKKLLDDAISQAQHQPRHVLLVDRGLAKMARVSGRDVDFASLRHQ
                     HIGARVPVAWLESNETSCILYTSGTTGKPKGVQRDVGGYAVALATSMDTIFGGKAGGV
                     FFCASDIGWVVGHSYIVYAPLLAGMATIVYEGLPTWPDCGVWWKIVEKYQVSRMFSAP
                     TAIRVLKKFPTAEIRKHDLSSLEVLYLAGEPLDEPTASWVSNTLDVPVIDNYWQTESG
                     WPIMAIARGLDDRPTRLGSPGVPMYGYNVQLLNEVTGEPCGVNEKGMLVVEGPLPPGC
                     IQTIWGDDGRFVKTYWSLFSRPVYATFDWGIRDADGYHFILGRTDDVINVAGHRLGTR
                     EIEESISSHPGVAEVAVVGVKDALKGQVAVAFVIPKESDSLEDRDVAHSQEKAIMALV
                     DSQIGNFGRPAHVWFVSQLPKTRSGKMLRRTIQAICEGRDPGDLTTIDDPASLDQIRQ
                     AMEE"
     gene            complement(29872..31323)
                     /gene="prpD"
                     /locus_tag="RHX21_001043"
     CDS             complement(29872..31323)
                     /gene="prpD"
                     /locus_tag="RHX21_001043"
                     /EC_number="4.2.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate dehydratase"
                     /protein_id="HDV1986267.1"
                     /translation="MSAQINNIRPEFDREIVDIVDYVMNYEISSKVAYDTAHYCLLDT
                     LGCGLEALEYPACKKLLGPIVPGTVVPNGVRVPGTQFQLDPVQAAFNIGAMIRWLDFN
                     DTWLAAEWGHPSDNLGGILATADWLSRNAVASGKAPLTMKQVLTAMIKAHEIQGCIAL
                     ENSFNRVGLDHVLLVKVASTAVVAEMLGLTREEILNAVSLAWVDGQSLRTYRHAPNTG
                     TRKSWAAGDATSRAVRLALMAKTGEMGYPSALTAPVWGFYDVSFKGESFRFQRPYGSY
                     VMENVLFKISFPAEFHSQTAVEAAMTLYEQMQAAGKTAADIEKVTIRTHEACIRIIDK
                     KGPLNNPADRDHCIQYMVAIPLLFGRLTAADYEDNVAQDKRIDALREKINCFEDPAFT
                     ADYHDPEKRAIANAITLEFTDGTRFEEVVVEYPIGHARRRQDGIPKLVDKFKINLARQ
                     FPTRQQQRILEVSLDRTRLEQMPVNEYLDLYVI"
     gene            complement(31357..32526)
                     /gene="prpC"
                     /locus_tag="RHX21_001044"
     CDS             complement(31357..32526)
                     /gene="prpC"
                     /locus_tag="RHX21_001044"
                     /EC_number="2.3.3.16"
                     /EC_number="2.3.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate synthase"
                     /protein_id="HDV1986268.1"
                     /translation="MSDTTILQNSTHVIKPKKSVALSGVPAGNTALCTVGKSGNDLHY
                     RGYDILDLAEHCEFEEVAHLLIHGKLPTRDELAAYKTKLKALRGLPANVRTVLEALPA
                     ASHPMDVMRTGVSALGCTLPEKEGHTVSGARDIADKLLASLSSILLYWYHYSHNGERI
                     QPETDDDSIGGHFLHLLHGEKPSQSWEKAMHISLVLYAEHEFNASTFTSRVIAGTGSD
                     MYSAIIGAIGALRGPKHGGANEVSLEIQQRYETPDEAEADIRKRVENKEVVIGFGHPV
                     YTIADPRHQVIKRVAKQLSQEGGSLKMYNIADRLETVMWESKKMFPNLDWFSAVSYNM
                     MGVPTEMFTPLFVIARVTGWAAHIIEQRQDNKIIRPSANYVGPEDRQFVALDKRQ"
     gene            complement(32571..33461)
                     /gene="prpB"
                     /locus_tag="RHX21_001045"
     CDS             complement(32571..33461)
                     /gene="prpB"
                     /locus_tag="RHX21_001045"
                     /EC_number="4.1.3.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylisocitrate lyase"
                     /protein_id="HDV1986269.1"
                     /translation="MSLHSPGKAFRAALTKENPLQIVGTINANHALLAQRAGYQAIYL
                     SGGGVAAGSLGLPDLGISTLDDVLTDIRRITDVCSLPLLVDADIGFGSSAFNVARTVK
                     SMIKAGAAGLHIEDQVGAKRCGHRPNKAIVSKEEMVDRIRAAVDAKTDPDFVIMARTD
                     ALAVEGLDAAIERAQAYVEAGAEMLFPEAITELAMYRQFADAVQVPILANITEFGATP
                     LFTTDELRSAHVAMALYPLSAFRAMNRAAEHVYNVLRQEGTQKSVIDTMQTRNELYES
                     INYYQYEEKLDDLFARSQVK"
     gene            33700..35286
                     /gene="prpR"
                     /locus_tag="RHX21_001046"
     CDS             33700..35286
                     /gene="prpR"
                     /locus_tag="RHX21_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate catabolism operon regulatory protein
                     PrpR"
                     /protein_id="HDV1986270.1"
                     /translation="MAHPPRLNDDKPVIWTVSVTRLFELFRDISLEFDHLANITPIQL
                     GFEKAVTYIRKKLANERCDAIIAAGSNGAYLKSRLSVPVILIKPSGYDVLQALAKAGK
                     LTSSIGVVTYQETIPALVAFQKTFNLRLDQRSYITEEDARGQINELKANGTEAVVGAG
                     LITDLAEEAGMTGIFIYSAATVRQAFSDALDMTRMSLRHNTHDATRNALRTRYVLGDM
                     LGQSPQMEQVRQTILLYARSSAAVLIEGETGTGKELAAQAIHREYFARHDARQGKKSH
                     PFVAVNCGAIAESLLEAELFGYEEGAFTGSRRGGRAGLFEIAHGGTLFLDEIGEMPLP
                     LQTRLLRVLEEKEVTRVGGHQPVPVDVRVISATHCNLEEDMRQGQFRRDLFYRLSILR
                     LQLPPLRERVADILPLAESFLKVSLAALSAPFSAALRQGLQASETVLVHYDWPGNIRE
                     LRNMMERLALFLSVEPTPDLTPQFLQLLLPELARESAKTPAPRLLTPQQALEKFNGDK
                     TAAANYLGISRTTFWRRLKS"
     gene            complement(35387..35662)
                     /locus_tag="RHX21_001047"
     CDS             complement(35387..35662)
                     /locus_tag="RHX21_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDV1986271.1"
                     /translation="MKIISKMLVGALAFAVTNVYAAELMTKAEFEKVESQYEKIGDIS
                     TSNEMSTADAKEDLIKKADEKGADVLVLTSGQTDNKIHGTANIYKKK"
     gene            35809..36480
                     /locus_tag="RHX21_001048"
     CDS             35809..36480
                     /locus_tag="RHX21_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysE family transporter"
                     /protein_id="HDV1986272.1"
                     /translation="MMKLLHLFMDEITMDPLHAVYLTVGLFVITFFNPGANLFVVVQT
                     SLASGRRAGVLTGLGVALGDAFYSGLGLFGLATLITQCEEIFSLIRIVGGAYLLWFAW
                     CSMRRQSTPQMSTLQQPISAPWYVFFRRGLITDLSNPQTVLFFISIFSVTLNAETPTW
                     ARLMAWAGIVLASIIWRVFLSQAFSLPAVRRAYGRMQRVASRVIGAIIGVFALRLIYE
                     GVTQR"
     gene            complement(36497..36742)
                     /locus_tag="RHX21_001049"
     CDS             complement(36497..36742)
                     /locus_tag="RHX21_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414861.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986273.1"
                     /translation="MAVQLFKTLLNQIPLLSSLQSGTLPLFGYSGRGRPMKKAHTGES
                     GLKWEAKDSSKLIGNKDHALRGLSSPMAGIRQIRLIT"
     gene            complement(37155..37970)
                     /locus_tag="RHX21_001050"
     CDS             complement(37155..37970)
                     /locus_tag="RHX21_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986274.1"
                     /translation="MISLKAPHNNLMPYTQQSILNTVKNNQLPEDIKSSLVSCVDIFK
                     VLIKQYYDYPYDCRDDLVDDDKLIHLMAAVRDCEWLDDNALTINVQFNDFPGFYDWMD
                     YPDHPVKFVFRILENQKGTVWVYDQDDAFLDIKANVQAGRFTGLKKLVQFIDSVRTDC
                     KCILLEHHMPLLRIFPKGKECMRVEKWLREMSSIPETDAPIKQALAHGLLLHLKNIHP
                     VFPESLVMLLLSVLDVKTYRDDARLNEWISNRVQELGDRYYPVNKHVKIRYTL"
     gene            complement(38213..39262)
                     /gene="yahK"
                     /locus_tag="RHX21_001051"
     CDS             complement(38213..39262)
                     /gene="yahK"
                     /locus_tag="RHX21_001051"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent aldehyde reductase YahK"
                     /protein_id="HDV1986275.1"
                     /translation="MKIKAVGAYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDL
                     HQVRSEWAGTVYPCVPGHEIVGRVVAVGDQVEKHAPGDLVGVGCIVDSCKHCEECEDG
                     LENYCDHMTGTYNSPTPDEPGHTLGGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAG
                     ITTYSPLRHWQAGPGKKVGVVGIGGLGHMGIKLAHAMGAHVVAFTTSEAKREAAKALG
                     ADEVVNSRNADEMAAHLKSFDFILNTVAAPHNLDDFTTLLKRDGTMTLVGAPATPHKS
                     PEVFNLIMKRRAIAGSMIGGIPETQEMLDFCAEHGIVADIEMIRADQINEAYERMLRG
                     DVKYRFVIDNRTLTD"
     gene            complement(39349..40305)
                     /locus_tag="RHX21_001052"
     CDS             complement(39349..40305)
                     /locus_tag="RHX21_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV1986276.1"
                     /translation="MKKSWRNNVEFYLIGLLVLTVAAFSITMPEIFWSISNFQSVASQ
                     MPVLGILALAMAVTMLCGGINLSIIATANACSLVMAWVATQYPPGIATVVATLLAGAG
                     AAVIIGLCNGVLIAGIRVSPILATLGMMTLLKGINILVTGGSAIANYPSWVLWLNHAQ
                     WFGIPLPMWLFAAVALGLWILLEKTPLGKAIYLIGSNERATLYSGINTRRVLIWVYVI
                     SALLCAVAAFLMMSKLNSAKASYGESYLLVSILAAVLGGVNPDGGSGRIIGMVLALFL
                     LQIIESGFNILGISPYLTMALWGTLLLCFIQVRGMLGLDRVV"
     gene            complement(40302..41273)
                     /locus_tag="RHX21_001053"
     CDS             complement(40302..41273)
                     /locus_tag="RHX21_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV1986277.1"
                     /translation="MAELKKRHEFWLALLIVVLFVGLAWRSDEFLTFGNLYDLANNYA
                     MLTILACGLFVVLISGGIDISFPAMTIIAQYGMVLLLQKIGGNFAVAFALAGCIGILL
                     GLINALLVNRLRVPSIIITISTLNIFYGLLLWLSKGVWLYDFPPWFEQGVMLFKYTDA
                     DGYDYGLGLPLIAMITVVLLTAFIMNFTSVGRKIYALGGNRESASRIGFSVLKLQLFV
                     YGYMGLMSGAAGVVQSWTVMTVAPDSLLGYELTVLAAVVLGGTSLLGGRGTLTGTLLG
                     VVLLAVMQNGLNLLGVSSYWQTLITGIIIVASISATAWSQHQNRSLL"
     gene            complement(41266..42750)
                     /locus_tag="RHX21_001054"
     CDS             complement(41266..42750)
                     /locus_tag="RHX21_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDV1986278.1"
                     /translation="METFLSLRHINKTFHATRALRDVSLDFMSGEVHCLAGQNGCGKS
                     TLIKIMSGVYRPDEGAEITLGGKNWSKLTPAASVAQGIQVIYQDLSLFPNLSVWENIA
                     VNHYHHGLFVNRRRLREVAQAAMTSINVTLPLDTLVSELSIARCQLVAICRALAQDAR
                     LIVMDEPTASLTHQEVQGLLQVVHQLRERGICVVFVSHRLEEVMEVSDRISVLKDGEL
                     VGTFPAAEMTTKQLGFLMTGQEFEYQVRELWQGKSSTPVLEVRNLSRHGEYLNINLRV
                     EAGEVVSIVGLLGAGRTELCLSLFGMTRPDAGEILINGQPVTLHSNQDAIRHGIGYVS
                     EDRMSRGLVMAQSIEDNIISTVFHKVKDRFGFLSETKVRDLVDRLIKALTIKVSDPHL
                     PVNTLSGGNAQRVSIAKWLAIGPRLLILDSPTVGVDIANKAGIYGIISDLAAHGIAVL
                     MICDEIEEAWYQSHRILVMQKGQITHSFLPDSSSQARIAEVVNG"
     gene            complement(42799..43782)
                     /locus_tag="RHX21_001055"
     CDS             complement(42799..43782)
                     /locus_tag="RHX21_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter substrate-binding
                     protein"
                     /protein_id="HDV1986279.1"
                     /translation="MNKRFVINMVSSLLLGAALISAPLQAAEKVVVNISKVDGMPWFN
                     RMGEGVVEAGNAFGVNASQVGPSSTDAPQQVKIIEDLIARKVNAITIVPNDANVLEPV
                     FKKARDAGIVVLTNESPGQPSANWDIEIIDNEKFAAEYVEHMAKRMGGKGGYVIYVGS
                     LTVPQHNLWADLLVKYQKEHYPDMHEVTRRMPVAESVDDSRRTTLDLMKTYPDLKAVV
                     SFGSNGPIGAGRAVKEKRAKNKVAVYGMMIPSQAASLIKSGDITEGITYDPASAGYAL
                     AAVASTLLKGEEIKPGLEMQNLGKADVDMDKRIIRFHKVLLVNKDNIDSLY"
     gene            complement(44036..44446)
                     /locus_tag="RHX21_001056"
     CDS             complement(44036..44446)
                     /locus_tag="RHX21_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HDV1986280.1"
                     /translation="MTIKEKFSQKYPHASFCTFGDSAALADHLATLIATGVKTASCGS
                     LAGCIEDNAFPMIGEYKIVENSRGEPVCVIRVIGLHLLRFSDVTVELARKEGEGDLSL
                     EYWRNEHRRFFQAEGSYSPEMDVIFEEYALIDVV"
     gene            complement(44745..46127)
                     /locus_tag="RHX21_001057"
     CDS             complement(44745..46127)
                     /locus_tag="RHX21_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDV1986281.1"
                     /translation="MKESNSRREFLSQSGKMVTAAALFGTSVPLAHAAVAGTLNCEAN
                     NTMKITDPHYYLDNVLLETGFDYENGVAVQTRTARQTVEIQDGKIVALRENKQHPDAT
                     LPHYDAGGKLMLPTTRDMHIHLDKTFYGGPWRSLNRPAGTTIQDMIKLEQKMLPELQP
                     YTQERAEKLIDLLQSKGTTIARSHCNIEPVSGLKNLQNLQAVLARRQAGFECEIVAFP
                     QHGLLLSKSEPLMREAMQAGAHYVGGLDPTSVDGAMEKSLDTMFQIALDYDKGVDIHL
                     HETTPSGVAAINYMVETVEKTPQLKGKLTISHAFALATLNEQQVDALANRMAAQQISI
                     ASTVPIGTLHMPLKQLHDKGVKVMTGTDSVIDHWSPYGLGDMLEKANLYAQLYIRPNE
                     QNLSRSLFLATGDVLPLNEKGERVWPKAQDDASFVLVDASCSAEAVARISPRTATFHK
                     GQLVWGSVAG"
     gene            complement(46137..47087)
                     /locus_tag="RHX21_001058"
     CDS             complement(46137..47087)
                     /locus_tag="RHX21_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase family protein"
                     /protein_id="HDV1986282.1"
                     /translation="MKELVVVAIGGNSIIKDNASQSIEHQAEAVKAVADTVLEMLASD
                     YDIVLTHGNGPQVGLDLRRAEIAHEREGLPLTPLANCVADTQGGIGYLIQQALNNRLA
                     RHGEKKAVTVVTQVEVDKNDPGFAHPTKPIGAFFSESQRDKLQKANPDWCFVEDAGRG
                     YRRVVASPEPKRIVEAPAIKALIQQGFVVIGAGGGGIPVVRTEAGDYQSVDAVIDKDL
                     STALLAREIHADILVITTGVEKVCIHFGKPQQQALDRVDIATMTRYMQEGHFPPGSML
                     PKIIASLTFLEQGGKEVIITTPECLPAALRGETGTHIIKT"
     gene            complement(47230..48648)
                     /locus_tag="RHX21_001059"
     CDS             complement(47230..48648)
                     /locus_tag="RHX21_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 domain-containing protein"
                     /protein_id="HDV1986283.1"
                     /translation="MSQSLFSQPLNVINVGIAMFSDDLKKQHVEVTQLDWTPPGQGNM
                     QVVQALDNIADSPLADKIAAANQQALERIIQSHPVLIGFDQAINVVPGMTPKTILHAG
                     PPITWEKMCGAMKGAVTGALVFEGLAKDLDEATELAASGEITFSPCHEHDCVGSMAGV
                     TSASMFMHIVKNKTYGNIAYTNMSEQMAKILRMGANDQSVIDRLNWMRDVQGPMLRDA
                     MKIIGEIDLRLMLAQALHMGDECHNRNNAGTTLLIQALTPGIIQAGYSVEQQREVFEF
                     VASSDYFSGPTWMAMCKAAMDAAHGIEYSTVVTTMARNGVEFGLRVSGLPGQWFTGPA
                     QQVIGPMFAGYKPEDSGLDIGDSAITETYGIGGFAMATAPAIVALVGGTVEEAIDFSR
                     QMREITLGENPNVTIPLLGFMGVPSAIDITRVGSSGILPVINTAIAHKDAGVGMIGAG
                     IVHPPFACFEKAILGWCERYGV"
     gene            complement(48648..50195)
                     /gene="fdrA"
                     /locus_tag="RHX21_001060"
     CDS             complement(48648..50195)
                     /gene="fdrA"
                     /locus_tag="RHX21_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase FdrA"
                     /protein_id="HDV1986284.1"
                     /translation="MSVKIVIKPNTYFDSVSLMSISTRANKLDGVEQAFVAMATEMNK
                     GVLKNLGLLTPELEQAKNGDLMIVINGKSGADNEQLLAEIEELFNSKAQSGSHEARYA
                     TIASAKKHIPESNLAVISVNGLFAAREARQALQNDLNVMLFSDNVSVEDELALKQLAH
                     EKGLLMMGPDCGTAIINGAALCFGNAVRRGNIGIVGASGTGSQELSVRIHEFGGGVSQ
                     LIGTGGRDLSEKIGGLMMLDAIGMLENDPQTEIIVLISKPPAPAVARKVLERARACRK
                     PVVVCFLGRVETPVDEQGLQFARGSKEAALKAVMLSGVKQENLDLHTLNQPLIADVRA
                     RLQPQQKYIRGLFCGGTLCDETMFAVMEKHGDVYSNIQPDPEFRLQDINRSIKHTFLD
                     FGDDDFTNGKPHPMIDPTNRISRLIEEARDPEVAVIVMDFVLGFGSHEDPVGSTIEAI
                     KEAKAIAAAEGRELIILAYVLGTDLDTPSLEQQSQMLLDAGVILASSSTNTGLLAREF
                     ICKGEEA"
     gene            complement(50185..51048)
                     /locus_tag="RHX21_001061"
     CDS             complement(50185..51048)
                     /locus_tag="RHX21_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 domain-containing protein"
                     /protein_id="HDV1986285.1"
                     /translation="MWALTADADFLAQRGQGQVEQVFARAVNIALPARQQLLTLLCEE
                     YDNAPNSCRLALTHFDDLFRHGDKVQFDDQGITVGQHLHIEMSRCRRWLSPTLQMTAV
                     NFHLIAWQQWHDIIHQHLGENETLFNYRGDNPFYQALNKELHIKRRAVIQAVNEKQNI
                     AAAVASMMGLGIGLTPSADDYLTGLVLILFISGHPAEKYKEEFYRGLQRGRNNTTLLS
                     AITLEAALQQRCRENIHHFIHDIIYGVPGNSTQAIEKIKHIGSSSGCDMLYGMADGCA
                     LSQTYGGNYVS"
     gene            complement(51088..51693)
                     /locus_tag="RHX21_001062"
     CDS             complement(51088..51693)
                     /locus_tag="RHX21_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ankyrin repeat domain-containing protein"
                     /protein_id="HDV1986286.1"
                     /translation="MSIKNLPADYLLAAQQGDIDKVKTCLALGVDINTCDRQGKTAIT
                     LASLYQQYACVQALIDAGADINKQDHTCLNPFLISCLNDDLTLLRIILPAKPDLNCVT
                     RFGGVGLTPACEKGHLSIVKELLAHTEINVNQTNHVGWTPLLEAIVLNDGGIKQQAIV
                     QLLLEHGASPHLTDKYGKTPLELARERGFEEIAQLLIAAGA"
     gene            51951..52448
                     /locus_tag="RHX21_001063"
     CDS             51951..52448
                     /locus_tag="RHX21_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HDV1986287.1"
                     /translation="MNGLTATGVTVGICAGLWQLVSSHVGLSQGWELLGTIGFVAFCS
                     FYAAGGGKSGFIRSLAVNYSGMVWAFFAALAAGWLASVSGLSAFWASVITTVPFSAVV
                     VWQGRFWLLSFIPGGFLGMTLFFASGMNWTVTLLGFLAGNCVGIISEYGGQKLSEATT
                     KRDGY"
     gene            52540..53472
                     /locus_tag="RHX21_001064"
     CDS             52540..53472
                     /locus_tag="RHX21_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV1986288.1"
                     /translation="MNSIFTEENLLAFTTAARFGSFSKAADELGLTTSAISYTIKRME
                     TGLDVVLFTRNTRSIELTESGRYFFRKATDLLNDFHAIKRSIDTISQGIEARVRICIN
                     QLLYTPKHTARLLQVLKKQFPTCQITVTTEVYNGVWDAIINNQANIAIGAPDTLLDGG
                     GIDYTEIGAIRWAFAIAPDHPLAFMPEPIAESQLRLYPNIMVEDTAHTINKKVGWLLH
                     GQESILVPDFNTKCQCQILGEGIGFLPDYMVREAMTQSLLVTRQIHNPRQDSRMLLAT
                     QHSATGQVTQWIKKQFAPNGILTGIYQDLLHREN"
     gene            complement(53514..54602)
                     /locus_tag="RHX21_001065"
     CDS             complement(53514..54602)
                     /locus_tag="RHX21_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDV1986289.1"
                     /translation="MASHDLSVFLEEFGATVNLTLPGIVSEKERLLLKLLMEGMSVTE
                     ISQYRNRSAKTISHQKKQLYEKLGIQSDITFWRDIFFQYHPQVISGTGNKNNFYIPDN
                     RCHHIVTPEAISLALENHEFKPWIQPVFCAQTGVLTGCEVLVRWEHPQTGIIPPDQFI
                     PLAESSGLIVIMTRQLMKQTADILMPVKHLLPDNFHIGINVSAGCFLAAGFEKECLNL
                     VKKLGNDKIKLVLELTERNPIPVTPEARAIFDSLHQHNITFALDDFGTGYATYRYLQA
                     FPVDFIKIDKSFVQMASVDEISGHIVDNIVELARKPGLSIVAEGVETQEQADLMIGKG
                     VHFLQGYLYSPPVPGNKFISEWVMKAGG"
     gene            complement(54744..58727)
                     /gene="ehaA"
                     /locus_tag="RHX21_001066"
     CDS             complement(54744..58727)
                     /gene="ehaA"
                     /locus_tag="RHX21_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin EhaA"
                     /protein_id="HDV1986290.1"
                     /translation="MNKIYRLKWNRSRNCWSVCSELGSRVKGKKSRAVLISAISLYSS
                     LVFADDVIVNQDKTIDFGKENQSIDYRITVTDNANLVINATDTSRPRLTLASGGGLDI
                     TGGKVTINGPLNFLLKGTGFLNVSNAGSELYADDLYESNSGMRHDRGYFNVSNGGKIH
                     VKGTSRLTYLQGNVSGEGSQVNSKTFFMGVYGSYGGNQYLSVNNGGEVNASEKISLGY
                     YDQNSDTTLAVSEGGKISAPTISLSTNSELALGAQEGSAAKAAGIIDAEKIEFVWAKT
                     SEKKITLNHTDKNATISADIVSDSEGLGYINALNGTTYLTGDNSAFSGKVTIEKNGAL
                     GITQNIGSAEITNRGKLHLKAEDSMTFANKISGNGTISIDSGTVELTGNNYAFYGYID
                     VASDAVAVISEDKNIGRAELDVDGKLQINANKDWVFDNDLEGRGIVEINMGNHEFSFD
                     EFAYTDWFQGSLAFQNTTFNLEKNAEFLQKGGITAGQGSLVTVGKGAHSISTLGFSGG
                     TVDFGALAAGAQMTEGTVNVSKTLDLRGEGVIQVSDSDVVRSVSRDIDSALSLTEVDD
                     GNSTIKLVDAQGAEVLGDAGNLQLQDKNGQILSSSAQRDIQQNGQKAAVGTYDYRLTS
                     GVNNDGLYIGYGLTQLDLHATDSDALVLSSNGKSENAADLSAKISGSGDLAFSSQKGQ
                     TVSLSNKDNDYTGVTDLRSGTLLLNNDNVLGNTHELRLAAETELDMNGHSQTVGTLNG
                     SADSLLSLNGGSLTVTNGGTSTGSLTGSGELNIQGGTLDIAGDNSNLTANVNIANSAN
                     VLVSHAQGLGSANVENNGTLALNNSTEKRAAASVNYTLGGNLTNNGTLMTGMSGQQAG
                     NVLVVKGNYHGNNGQLVMNTVLNGDDSVTDKLVVEGDTSGTTAVTVNNAGGIGAKTLN
                     GIELIHVDGKSEGEFVQAGRIVAGAYDYTLARGQGANSGNWYLTSGSDSPELQPEPDP
                     MPNPEPNPNPEPNPNPTPTPGPDLNVDNDLRPEAGSYIANLAAANTMFTTRLHERLGN
                     TYYTDMVTGEQKQTTMWMRHEGGRNKWRDGSGQLKTQSNRYVLQLGGDVAQWSQNGSD
                     SWHVGVMAGYGNSDSKTISSRTGYRAKASVNGYSTGLYATWYADDESRNGAYLDSWAQ
                     YSWFDNTVKGDDLQSESYKSKGFTASLEAGYKHKLAEFNGSQGTRNEWYVQPQAQVTW
                     MGVKADKHRESNGTLVHSNGDGNVQTRLGVKTWLKSHHKMDDGKSREFQPFVEVNWLH
                     NSKDFSTSMDGVSVTQDGARNIAEIKTGVEGQLNANLNVWGNVGVQVADRGYNDTSAM
                     VGIKWQF"
BASE COUNT        14081 a        15977 c        14695 g        14254 t
ORIGIN      
        1 cccagtcgaa cctccgggtc tgaaagccct tgcttttcag ttattagcaa catttaacat
       61 ttataaatta acatctggct gcgccagaga ttacgtctct gagtgcatcg ttgtgcttgt
      121 agtataataa ataaaatgga gtgtcattaa gtggataagg ttttagattc agccctcctt
      181 tcttcggcaa ataaaagaaa gggtatcctt gctattggcg cacatcctga cgatatagaa
      241 ttaggctgtg gcgcatcgct tgctcgtctt gcgcaaaaag gaatttatat cgcagcagtg
      301 gtgatgacta ccggcaactc tggtacagat ggaataatcg atcgccatga agaatcgcgc
      361 aacgccctaa agatattagg gtgccaccaa actattcatc ttaattttgc tgacacccgc
      421 gctcatttac agctcaatga tatgatttcc gccctggaag acatcattaa aaatcaaatt
      481 ccttctgatg ttgaaatcat gcgggtatat accatgcatg atgccgaccg ccatcaggat
      541 catctcgctg tttatcaagc ttcaatggtt gcctgccgca ctattccaca aattctcggc
      601 tacgaaaccc caagtacctg gctttcattt atgcctcagg tttttgaatc cgttaaagaa
      661 gaatatttca cagtcaaact tgctgcatta aaaaaacata aaagccagga acgacgtgat
      721 tatatgcgtc atgatcgcct gcgtgcagtt gcacaatttc gcgggcaaca ggtcaatagc
      781 gatctgggtg aaggctttgt aattcataaa atgattcttt gagcaaattg catgaaaacc
      841 tggatattta tctgtatgtc catagcaatg ttgctatggt ttttaagtac gctaagacgt
      901 aaacccagtc aaaagaaagg ctgtattgac gccattatac ctgcgtataa cgaaggcccg
      961 tgtctggcgc agtcactgga taatctactg cgtaaccctt atttttgccg ggtaatttgc
     1021 gttaacgacg gctccacgga caataccgaa gcggtcatgg cggaagtcaa acgcaaatgg
     1081 ggcgaccgct ttgttgccgt cacgcaaaaa aatactggta aaggtggtgc gctgatgaat
     1141 ggcctcaatt atgccacctg cgaccaggtt tttttaagtg atgccgacac ctatgttccg
     1201 cccgatcaag acggaatggg ctatatgctg gcagaaattg agcgcggtgc tgatgccgta
     1261 ggcggcattc cctctactgc gttgaaaggc gcggggctgt taccgcacat ccgcgcgacc
     1321 gtaaagttgc cgatgattgt tatgaagcgc acgctacagc agctcctggg cggcgcaccg
     1381 tttattatca gcggtgcctg cgggatgttc cgtactgatg tattgcgtaa gttcggtttc
     1441 tcggatcgta ctaaagtcga agaccttgat ctcacctgga cattagtggc aaacggctac
     1501 cgtattcggc aggcgaatcg ctgcatcgta tacccacagg aatgcaacag tccgcgtgag
     1561 gagtggcgtc gctggcggcg ttggattgtg ggatacgcgg tctgtatgcg cctgcataaa
     1621 agacttttat ttagccgctt cggtatcttc agtatatttc ctatgctgtt ggttgtgatt
     1681 tatggcgttg ggatttatct cactacctgg tttaatgaat tcatcaccac cgggccgcat
     1741 ggtgtggtgt tggcaatgtt tccgcttatc tggatcggcg tagtttgtgt tattggtgct
     1801 tttagcgcct ggtttcatcg ttgctggttg ttggtgcctt tagcgccgct ttccgttgtg
     1861 tatgtattat tagcttatgc catctggatt atttatggac ttattgcctt ttttactgga
     1921 cgcgaacctc agcgcgacaa acccacccgc tattccgcac tggtggaagc gtcaaccgct
     1981 tattcccaac cttctgtcac aggaactgaa aaactatctg aagcttaatg ttaaagagaa
     2041 aaatattcag attgcagacc aggtaattat tgatgaaact gcaggtgaag ttgttatcgg
     2101 cgcgaatacc cgtatttgtc atggtgccgt tattcagggt ccggtagtga ttggcgcaaa
     2161 ctgcctgata ggtaattatg cgtttattcg tcctggcaca ataatcagca atggtgtaaa
     2221 aattggtttt gccaccgaaa ttaaaaatgc ggttattgaa gcggaagcaa cgattggtcc
     2281 gcaatgtttt attgccgact cggtagttgc aaaccaggca tatttgggcg cacaagtacg
     2341 taccagtaat catcgtctgg atgaacagcc tgtgtctgtt cgaactccag agggaattat
     2401 cgctaccgga tgcgataaat taggttgtta tatcgggcag cgttcacgcc ttggcgtaca
     2461 agttataatt ttgcctgggc gaattatttc cccgaacacg caacttggcc cgcgcgtgat
     2521 tgtagaacgt aatttacctg ccggaactta ttcactccga caagaactta tccgtacagg
     2581 agattaaaat gataaaacgg acgttattag cggcggccat ttttagcgca ttgcccgctt
     2641 atgccgggtt aacttccatt accgcgggct acgattttac cgattattct ggcgatcatg
     2701 gcaaccgtaa tttagcgtat gctgaactgg tggcgaaagt tgaaaacgca acgctgcttt
     2761 ttaatctttc ccaggggcgt cgtgattatg aaactgaaaa tttcaatgcc actcgcggtc
     2821 agggtgcggt ctggtataaa tggaataact ggctgacaac ccgaacgggt attgcctttg
     2881 cggataatac gccggtcttt gcccgccagg attttcgtca ggatattaac ctggccctgt
     2941 tgccaaaaac gcttttcacg accggttatc gctacactaa atattacgat gatgtcgaag
     3001 tcgatgcctg gcaaggcggc gtatcactct atactggccc ggtgatcacc agctaccgct
     3061 atacccatta tgactccagc gatgcaggtg gtagttatag caatatgatt tccgtgcgtc
     3121 tgaatgaccc gcgcggcact ggttatacgc aactatggct aagccgcgga acaggcgctt
     3181 acacctatga ctggacgcca gaaacacgct acggcagcat gaagagcgtc agtttgcaac
     3241 gtattcaacc gctgactgag caacttaatc tcgggctgac ggcaggtaaa gtgtggtacg
     3301 acaccccaac cgatgattat aacggtctgc aacttgcagc ccatctgacc tggaaattct
     3361 gattccttct gccgcccgct atccggggcg gccttccctg ccgattagcc ccccctttcc
     3421 tctttgtttt ccgaccacat tcaccggata aattttattc tccagtgtta tatactatag
     3481 gggggtatgc attgacatat agcatacccc cctatagtat attgcgtgca gatgatgagg
     3541 tgcgaaatgc ccagtactcc ggaagagaag aaaaaggtcc ttactcgagt tcgtcgtatt
     3601 cgagggcaga ttgatgctct ggaacggtcg ctggagggtg atgccgaatg ccgtgccata
     3661 ctccaacaga tcgctgccgt tcggggcgcg gctaacgggc tgatggcaga agtgcttgaa
     3721 agccatatcc gggaaacgtt tgaccgaaat gactgctaca gccgcgaagt cagccaatcc
     3781 gttgacgaca ctattgaact ggttcgagcc tatcttaaat agctgaatct attaccatat
     3841 tgaggaagag cgagagatga aatcacgtgc tgccgttgca tttgctcccg gtaaaccgct
     3901 ggaaatcgtt gaaattgacg ttgcaccacc gaaaaaaggt gaagtgctga ttaaagtcac
     3961 ccataccggc gtttgccata ccgacgcatt taccctctcc ggggatgacc cggaaggtgt
     4021 attcccggtg gttctcggtc acgaaggggc cggcgttgtg gttgaagtcg gtgaaggcgt
     4081 aaccagcgtc aaacctggcg accatgtgat cccgctttac accgcggagt gcggcgagtg
     4141 tgagttctgt cgttctggca aaactaacct ctgtgttgcg gttcgcgaaa cccagggtaa
     4201 aggcttgatg ccagacggca ccacccgttt ttcttacaac gggcagccgc tttatcacta
     4261 catggggtgc tctacattca gtgaatacac cgtggtcgcg gaagtgtctc tggccaaaat
     4321 taatccagaa gcaaaccatg aacacgtctg tctgctgggc tgtggcgtga ccaccggtat
     4381 tggcgcggtg cacaacacag ctaaagtcca gccaggtgat tctgttgccg tgtttggtct
     4441 tggcgcgatt ggtctggcag tggttcaggg cgcacgtcag gcgaaagcgg gacggattat
     4501 cgctatcgat accaacccga agaaattcga tctggcgcgt cgcttcggtg ctaccgactg
     4561 cattaacccg aatgactacg acaaaccgat taaagatgtc ctgctggata tcaacaaatg
     4621 gggtatcgac catacctttg aatgcatcgg taacgtcaac gtgatgcgtg cggcgctgga
     4681 aagtgcgcac cgcggctggg gtcagtcggt gatcatcggg gtggcaggtt ctggtcagga
     4741 aatctccacc cgtccattcc agttggtcac tggtcgcgta tggaaaggtt ccgcgtttgg
     4801 cggcgtgaaa ggtcgttccc agttaccggg tatggttgaa gatgcgatga aaggtgatat
     4861 cgatctggaa ccgtttgtca cgcataccat gagccttgat gaaattaatg acgccttcga
     4921 cctgatgcat gaaggcaaat ccattcgaac cgtaattcgt tactgatttc ccgcaggtat
     4981 accccgtcca cttcagacgg ggttcttaat actctccccg ggcagccgtc cgggggatta
     5041 accgtgagat aatgactgat ggaactcatt gaaaaacatg ccagctttgg cggctggcaa
     5101 aatgtgtatc ggcattattc ccaatcactg aaatgtgaaa tgaatgtcgg cgtctatctc
     5161 ccaccaaaag ccgcgaatga aaaattgccg gtgctgtact ggctttcggg cctgacctgc
     5221 aacgagcaga atttcattac taaatcgggg atgcagcgtt acgcggctga gcacaacatt
     5281 attgttgttg cgccggacac cagtccgcga ggcagtcatg tcgcagatgc cgaccgttac
     5341 gatctcgggc aaggtgccgg gttttacctg aacgcaacgc aagcgccgtg gaatgaacat
     5401 tacaaaatgt atgactatat ccgcaacgag ctgccggatt tagtgatgca acattttccg
     5461 gcaacgacca gaaagtctat ctctggtcat tctatgggcg ggctgggcgc gctggtgctg
     5521 gcgttacgta acccagatga atatgtcagc gtctcggcgt tttcgcccat tgtctcccca
     5581 tcgcaagtac cgtggggaca gcaagccttt gccgcatatc ttggtgaaaa taaagatgcc
     5641 tggttggatt acgatccggt gagtcttatt tcacaaggtc aacgcgttgc ggaaatcatg
     5701 gttgatcagg ggttgagtga tgatttttac gcggaacagc tgcggactcc aaatcttgaa
     5761 aagatctgcc aggagatgaa tatcaagacg ttaatccgtt atcacgaggg ttacgaccac
     5821 agctattatt ttgtctccag ttttattggc gagcatattg cctaccacgc caataaactg
     5881 aatatgcgtt gataatagtg cacgactgcc ggatgcggcg tgaacgcctt atccgcctac
     5941 atttcgcccg caggccgtag gcatgataag acgcgcatag cgtcgcatca ggcatctgcg
     6001 cacgacttat ctatgtttac cacatcaaat catcaggcac tttgaagtcg gcatacggat
     6061 cgtcttcatc ctgctcttcg gcactgagcg cgctgtgcaa cactatactg ctggcatcac
     6121 gctgagctat tttatcggca acgctggcgg gaataatggc gtattcacct tcgctattgt
     6181 tatcgaccaa caagcgagca atcgccagac gaccattaat caactgcgct tgtgtgagct
     6241 tatcgacaaa aatcttctta atcagattgc cgtcagtgaa gttaaaacca atatcgccat
     6301 tggcaatggt gattcggttc atttcaatga gctgcttcac ctgagcttta tattctttcg
     6361 ccaacgccgc ttgtttttgc tgttcgctaa gctgtttatc acgctcaagc tgtgcctttt
     6421 tattttcttc taccgccgcc cgagcttcac gcgcctgaac gcgcgatttt ttcgccgttc
     6481 tctcgacctt cgccgctttt ttgctggtga ctaatcctgc tttgagcaac tgctcttgta
     6541 aggtaagttt tgccatcttt gtttccaaac ccgctgaata atttttagcg agtatacctg
     6601 taaacgccgt gggtgtattg ggggcaagtc cctttcgccc ctgcttaata aggcgcgtca
     6661 ggcatcggca cacggctgca ttcttgatct ccgactcatc aaaataaaca ccgccaaccc
     6721 agcaacaaga atacccggtg cagaagcggc cattacgccg accgtgccag tgcctaatgc
     6781 cagcattttc ccggccagta acggaccgct catagccccc agacgcccta ccgccacggc
     6841 tgttcccaca cctgttgcgc ggatctgcga actgtaaaac aacggtgcca gggcatacaa
     6901 aacgctttgt ccacctgtcg caaacaaccc cgcgacaaat cccgccagca acataccgtt
     6961 aaatgacgac accgttccaa gcgccagcag cgaagctaac atgccgctat aaatcagtag
     7021 cgacatggtt actggacgca gcttatccat caatgcgccc aacattaacg tcccgcttgc
     7081 cgcccccatt tgcagggcaa acatcacccc tgccgcctgc gatggctgga atccttgctc
     7141 caccaaaagt agcggtagcc agttgatcaa catataaacc accagcagag tgaagaaata
     7201 acacaaccac agcagcagcg tcgcggttgc cgtttctggc gcaaataagg cacgcagtgg
     7261 tggcgcagcc tgtttttcgc cagcgaaaac cgctgactcc ggcagccagc gcattaatag
     7321 cggcaccaga atcaacggca ccacaccacc tacccaaaac accgtttgcc atgctaagtt
     7381 tgcccccgcg aaacccagtg tcgccgccag cgccgcgcca atgggaacac cgcaatacat
     7441 caggctcact gccgtcccac gaaaacgtgg acccgcggct tcagacgtca gggcgataag
     7501 attcggcaac gccgccccca gcccgacacc ggtcatcagc cgcgcaaaga ccagtgaggg
     7561 gaaatcccag gcaatcgccg ttgccagtga gaacaaacca aacagcgcaa ctgagccaat
     7621 caaaatacgc ttacgaccat aacggtctgc cagcatcccg ccaaccaacg cgccgggtag
     7681 caaaccgagt attccggcgc taaatatcca gcccatttgc attttatcga gtgcgaaagc
     7741 ctgggcgatg ccacccgccg caatgccagc cgcctgaaga tccagccctt ccatcagagc
     7801 gaccaaaaaa caaagcccga tggtcagcat caggcgggat gaagatgatg aaggggtacg
     7861 agtcgacata agatgaacct cattgcgagt gcaggtgaat cgcgactgat acattgccag
     7921 ccgcgtaatc agaactattt aatgactgcc tacgggcgaa atgtaggccg gataaggcgt
     7981 tcacgccgca tccggcagtc gtgctgggat gggcatacaa aatgcacgtt ctcggcagtc
     8041 atcattattt gttgttgcgc agatccagcg ccacgtcaac gatcatatcc tcctggccgc
     8101 caaccatccg gcgtttgccc agctcaacga gaatatccac cgcacttaag ccataacgcg
     8161 ccgccgccgt ttcacagtga cgcaggaagc tcgagtaaac accagcgtat cccagcgcca
     8221 gcgtttcgcg atcgactcgt accggtcgat cctgcaacgg acgcaccagg tcgtcggcgg
     8281 catccattaa cgcatagaga tcggtcccat gctgccagcc cagtttatcc gcggcggcaa
     8341 taaacacttc cagcggtgcg ttacctgcgc ccgcgcccat tcccgcgagg ctggcgtcga
     8401 ttcggtcgca gccctcttcc accgccgcga tagagttcgc cacgccaaga ctcaggttat
     8461 ggtgagcgtg catgccagtt tgcgtttctg gtttcagctc tgctttcagg gcgcggaaac
     8521 ggtcacggat atcgctcatg ttcatcgcac cgccagaatc caccacataa atacaggtcg
     8581 caccgtagcc ttccatcagc tttgcctgct ttgcgagatt ctccggcgtg gtcatatggc
     8641 tcatcatcag aaaaccaacg gtgtccattc cgagctcgcg ggcatactga atatgctggg
     8701 cggaaacatc agcttcggta cagtgcgttg ccacacgaac cacccgcgcg ccagcctgcc
     8761 aggcattttt cagatcgtga atagtgccga ttcctggcag caacaacgtc gcgattttgg
     8821 cgtgcttcac cacatccgcc gccgcttcaa tccattcaag gtcgctatgt gcgccgaaac
     8881 catagttaaa gctggaacct tgcaaaccgt cgccgtgggc cacttcaatc gaatccacgc
     8941 gggcatcgtc cagtgctttg gcaatctggc gaacgttttc cagcgaatac tgatgacgaa
     9001 tggcgtgcat accgtcacgc aatgtgacgt ccgagatata aagtttttta ccgttcatgc
     9061 cgcttctcct gccttgcgcg ccagtgactg ggccattttt tccgctgtcg ccagcgcact
     9121 ggaagtcata atgtcgaggt tgcccgcata ggcaggcaga taatgcgctg cgccttcgac
     9181 ttccagccag accgccgttt tcagcccgga gaactgaccc acgcccggca aattaaccgg
     9241 tttatcctgc gggataactt caaactgcac gcgctgtttc aggcgataac ccggtacgta
     9301 agcctgcacc gcctcagcca tttcattgat tgaggcttcg atatcatctt gtgaagcttc
     9361 gtcgctcaat acatacaccg tgtcacgcat catcaacggt ggctctgctg ggttaagcac
     9421 aataatcgcc ttcccttttg ccgcgccgcc caccacttca atggctcggg aagtggtttc
     9481 cgtaaattca tcgatattgg cacgcgtgcc aggtccggca gatttactgg cgatagaagc
     9541 gataatttcg gcgtaatgaa cacgcgccac gcgtgaaact gccgccacca ttggaatggt
     9601 ggcctggccg ccgcaggtga ccatgttgac gttcagttga tcgacgttcg cctcgaggtt
     9661 aaccaccggc acgcagtaag ggccgatggc agcaggcgtc aggtcaatta agcgaatatc
     9721 cggtttcgct tcgcgtaaag cggcatcgtt tttcacatgc gcgcccgcgc tggtcgcatc
     9781 aaatacaatg tcgatatcag caaattcagg catgttcatc agcccgatca ccccttcatg
     9841 ggtggtggcg acgcccatac gtctggcacg cgccagaccg tcggactgag gatcaatgcc
     9901 gaccatcacc gccatctcca gatgctgacc gtgacgcaaa attttaatca tcagatcggt
     9961 gccaatgttg ccagaaccga taatggcgac tttacgctta ctcatgacag acttcctttt
    10021 ggggctgcgc ttgaaaatgt cgcagcaact gaacctatgc cttcaatatg ggcttcaaaa
    10081 cgatcgcccg cattcactgc caccatcgga cctaatgccc cggtaagaat gatatctccg
    10141 gcgcgcagcg gttcacccag gctggccatt ttgcgtgcca gccagacggc ggcattaagc
    10201 ggatgtccca ggcattcgct gccgcgcccg ctggaaacct cttcgttatt acgcgtcatc
    10261 ttcatggcgc agtttttcag gtctaacccc gccggacgtt gcgccggacc gccgatgaca
    10321 tacaccccgc aggaagcgtt atctgccacg gtatcgacaa actgaatcga ccagtcgcga
    10381 atgcggctac ccaccacctc cagcgccgga agtacccatt caatggcgtt atacaattcg
    10441 tcgaaggtga tatcggttgc gggcaaatcg cggttcaaca ccagtgcgat ctccgcttca
    10501 atgcggggtt gcagaacacg ggaaaaagga atgatttcgt tatcgccata acacatgtcg
    10561 gcaaataatg tcccgaaatc cggttgatca acgcccagtt gttgctgcac tttcggatgc
    10621 gtcaggccca ctttacgccc taccacgcga cgcccctgcg caacgtcata ttgcacattt
    10681 atgtgctgaa tggcgtaggc cgcttcagcg ttatcgatac caatcagatc gcgcagcggc
    10741 gcaatcgctt cgccctgctc tgcggcgcgg cgtaaatccg ccgccagttg ctcaagagta
    10801 tgcttcgtca tgaccattcc ttaagggcgt gcgaggaaat tcagcaccaa ttgattgaaa
    10861 gcgtcggcat gttcccactg cgcccagtga ccacagtcgc ggaagatatg cagttcagaa
    10921 ccggcaatgc cggacagcag acgcagaccc gcatccatcg gcacaaagcg gtcgttgcgc
    10981 ccccagacaa tcagggtttg cgctttgatt tccgccagac gtgggccaaa atccgggaac
    11041 tgtttcggat tagcttccag gctcttaacg aagttttcca ggtgatcgcg gcgcgacagc
    11101 atattattca ggcgcgcttc aaacagggcg tcggtcaaat cgctggtatc gaaaacgaag
    11161 atatccatca tcagcttcag gttttcgata gtcggctgac gataaagctg attcagtcgc
    11221 ttaatacctt cggttggcat cggcgtaaac aaactcatgc cgcccgtacc gccgcccatc
    11281 agcaccagtt tgccgacgcg ctccggccag ttaagggtga acgccacaga actatggccg
    11341 cccatcgagt tgcccagcag gtggattttg gcgatatcca gttgatccac cacgcttttc
    11401 aggattcgtg cattaagatc cgatcgtgaa ccactattaa cgatcgaatc gcttttgccc
    11461 caacccggac aatccagcag gatcacccga tagcccgcct ctaccagcgg atcgatattg
    11521 cggctgaagt tcgcccagcc agtagcaccc gggccggaac catgcagcag gacaacggtt
    11581 tcgtcgcctt gtccgcagtc attaaaatgg atgcgcagcg ttttacccgc ttcttctaca
    11641 ttcagaaaac ggctggtggc ggcttcggtt tgtggctgat aactcatcat cttctcctgc
    11701 atattcagtt ctctgttctg gcgcttaacg agccaaatcc ggcaatccac tccgggattg
    11761 ggcggtaata acgcccttcg ctacgccagt tgccaaacgc agaaatagcg gcaaaagcgg
    11821 cgacccaggt tttgatttca tgtgtcgact ttccggcaat agcggaaagc tcttcgttac
    11881 tgacggcatc cagttcctgt atgcgtccct gctccagcaa agtcatgaac tggttatccc
    11941 aaatcgggtt gagcggatgc agagttctct gatcctcaac aaacttctca gcggcgctaa
    12001 tcacccgttg ctgacgcaat tcgcgctcac tggcgggtaa atctttcccg ctccccaaca
    12061 gacggtcgcg catatgggca tcggctttcg ccagttcggg caccggcggc tgatgggaaa
    12121 gcccaccgga acccaggaac agcacgcgtt tattgagagt gctggtgaaa cgtccaatgg
    12181 cttcacccaa catgcgggta cgctggaaac cgggcagcgg cgtggcgaca ccgttgatga
    12241 acacaggcag aactggcacc ttatccagcc caccgagcag gaactccagc ggctgggcga
    12301 acccgtggtc cacctgcata cagtaagaaa cggcaagatc gatcccgctc ttcatgacag
    12361 catgcgcaca ggcctccgcc agctccacag gcacgggcag ctctcctgcc gcactgccga
    12421 aatcaccaat tgccgtcgct ccaacgccta aacagaacgg tggcatcacg tcatagaaaa
    12481 agccgttgta gtgatctggc gcaaacagca ccaccagttc aggggagaaa gccgcaatac
    12541 gctcgcgggc gctggcaatc acgccattga cctcatcgag tacctcttgc gccgggtcga
    12601 cataccccac caacggcgag tgggaaagac agtgaagata agcgtgcata tcaggctacc
    12661 ttttcgacag aaacgtcggc atcagggcgg gtcagcgtca tcaccgacgc cagtttattc
    12721 agcgtattgc ccagggtttg cggaatggcg gtggcggcaa caaagcgatc cgggcgcatc
    12781 accaccagcg aagcattgtg ttgcgcgaac cagctacgca gacgaccttg cgtatcgccc
    12841 acgcgtagca cgccgtcgtg gttatcctgt gcggtatgaa tttgcacttc cggcaccacc
    12901 tgaatgaagc gtgtgcccaa cgcgcgccac tgctggattt gctcgtcgct catcccccac
    12961 agtggattgc atccccagcc aattaccgcg aagttcgcgc caatcgcgtt atcgagcagc
    13021 gtcacgtcgc cgttttccag cgtgactttc ggctgaataa acatcttgcc gaccggagag
    13081 tgcttcgctt cgccctcacg taccagcgca ccgccgtaat attgcggcat cggcttgaag
    13141 cgcatttcga ggaagtagcg ttttactggc ggcagataat tcagtagcca ggaaacgccg
    13201 tcacgtaacg taccctgcca gcgtttcggc ggagccagca cgttgcccgc cgtcacggac
    13261 aggtcaatca tcgctttggc gtgatcgcga cgttcttgtt gataggtatc gagcagcgca
    13321 tcgcgggctt tcccctggat aaccaacgcc agtttccagg cgaggttaaa ggcgtcgcgc
    13381 ataccactgt tatagccctg cccctgccat accggcatga tgtgcgcggc atcgcccgcc
    13441 agcagtacgc gatcaatacg gaaacgttgc gccagtcgcg cgttgtgggt gtagacacgc
    13501 tggcgaatca attcaacatt gtccggatta ggcagcactt tgcttaacag cttgcgcata
    13561 ttttgcggct cacgcagctg ttcttcggtt tctcccggca tcaccataaa ttcaaagcga
    13621 cgtaccgcat gaggcagcgc ggcagaaaca tacgggcgca ccggatcgca acataaatag
    13681 atatgcggcg tacttaacgg atcgttggcg atatccacca caatccactg atttggcgca
    13741 gttttacctt caaacggcac attcagggtg cgacgaacaa aacttgcccc accatcacag
    13801 gccaccagcc actgggcttt gactatttcc cgctgccctt ctgccgtttt caggtgcaag
    13861 gtcacttcgt cattttgctg gctgaaggcc tccagctcgc gggcaaacaa gcagcgcaca
    13921 ttcggaaaac gcgacaaccc ttccagcatc accgcatcga cctgtggctg aataaaggcg
    13981 ttacggcgcg gccagccaaa ttcatcggtc attggctgaa tatcagcaaa acagcggcct
    14041 tttggggtga gaaaacgcat cgcgtgccac ggtgtagtgt gcggcagaac attctcgacc
    14101 aggccgaccg actgcatggt gcgcagcgcc tcgtcatcaa taccaatcgc acgcgggtag
    14161 tcgatcaact tatcgagttt ctccaccacc agcacgtcaa tgcccatctg accgagatag
    14221 ttcgccatca tcagcccaac cggaccggca ccagcgatcg ccacctgaac gctatggtta
    14281 acagcaggct ggatgtcagg gtgttgtatt gccatttcag tacctcacga ctcggacaaa
    14341 atgccgttgc gcgcacagta cagcgcaact tattttgtta aaaaacatgt aaatgatttt
    14401 ttattgtgcg ctcagtatag gaagggtatt ttcggctaca atcaaaacat gcccgaatgt
    14461 gcaccaggtg cacaacgttg ttttaactat agaaatgtca attaatatgc agaacaatga
    14521 gcagacggaa tacaaaaccg tgcgcggctt aacccgcggt ctaatgttat taaatatgtt
    14581 aaataaactt gatggcggtg ccagcgtcgg gctgctggcg gaactcagcg gcctgcatcg
    14641 caccactgtg cggcgactgc tggagacgct gcaggaagag ggatatgtcc gccgtagccc
    14701 ctccgatgat agttttcgac tgaccatcaa agtgcggcaa ttaagcgaag gatttcgtga
    14761 cgaacagtgg atttctgcac tggcggcccc gctgctgggc gatctgttgc gcgaagtggt
    14821 atggccaaca gatgtgtcca ccctggatgt tgatgcaatg gtggtacgcg aaaccaccca
    14881 ccgtttcagc cgcttatcct ttcaccgggc aatggtcggg cgacgtttac cgctcctgaa
    14941 aaccgcctcg ggcctgacct ggctggcctt ttgcccggaa caagaacgca aggaattaat
    15001 cgaaatgtta gccgcccgcc ccggtgatga ctatcaactg gcacgagaac cgttaaagct
    15061 gcaagccatt ctggcgcgcg cgcgcaaaga gggttacgga cagaactacc gcggctggga
    15121 tcaggaggag aagattgcct ctatcgccgt accgctgcgc agtgaacaac gggtgattgg
    15181 ctgtctgaat ctggtgtata tggcgagcgc aatgaccatt gaacaggcag cggaaaagca
    15241 tcttccggcg ctacaacggg tagcaaaaca gatcgaagaa ggggttgaat cgcaggctat
    15301 tctggtggcc ggacggcgaa gcggcgtgca tttacgttga caccatcgaa tggcgcaaaa
    15361 cctttcgtgg tatggcatga tagcgcccgg aagagagtca attcagggtg gtgaatgtga
    15421 aaccagtaac gctatacgat gtcgcagagt atgccggtgt ctcttatcag accgtttctc
    15481 gcgtggtgaa ccaggccagc cacgtttctg cgaaaacgcg agaaaaagtg gaagcggcga
    15541 tggcggagct gaattacatt cccaaccgcg tggcacaaca actggcgggc aaacagtcgt
    15601 tgctgattgg cgttgccacc tccagtctgg ccctgcacgc gccgtcgcaa attgtcgcgg
    15661 cgattaaatc tcgcgccgat caactgggtg ccagcgtggt ggtgtcgatg gtagaacgaa
    15721 gcggcgtcga agcctgtaaa gcggcggtgc acaatcttct cgcgcaacgc gtcagtgggc
    15781 tgatcattaa ctatccgctg gatgaccagg atgccattgc tgtggaagct gcctgcacta
    15841 atgttccggc gttatttctt gatgtctctg accagacacc catcaacagt attattttct
    15901 cccatgaaga cggtacgcga ctgggcgtgg agcatctggt cgcattgggt caccagcaaa
    15961 tcgcgctgtt agcgggccca ttaagttctg tctcggcgcg tctgcgtctg gctggctggc
    16021 ataaatatct cactcgcaat caaattcagc cgatagcgga acgggaaggc gactggagtg
    16081 ccatgtccgg ttttcaacaa accatgcaaa tgctgaatga gggcatcgtt cccactgcga
    16141 tgctggttgc caacgatcag atggcgctgg gcgcaatgcg cgccattacc gagtccgggc
    16201 tgcgcgttgg tgcggatatc tcagtagtgg gatacgacga taccgaagac agctcatgtt
    16261 atatcccgcc gttaaccacc atcaaacagg attttcgcct gctggggcaa accagcgtgg
    16321 accgcttgct gcaactctct cagggccagg cggtgaaggg caatcagctg ttgcccgtct
    16381 cactggtgaa aagaaaaacc accctggcgc ccaatacgca aaccgcctct ccccgcgcgt
    16441 tggccgattc attaatgcag ctggcacgac aagtttcccg actggaaagc gggcagtgag
    16501 cgcaacgcaa ttaatgtgag ttagctcact cattaggcac cccaggcttt acactttatg
    16561 cttccggctc gtatgttgtg tgaaattgtg agcggataac aatttcacac aggaaacagc
    16621 tatgaccatg attacggatt cactggccgt cgttttacaa cgtcgtgact gggaaaaccc
    16681 tggcgttaca caacttaatc gccttgcggc acatccccct ttcgccagct ggcgtaatag
    16741 cgaagaagcc cgcaccgatc gcccttccca acagttgcgc agcctgaatg gcgaatggcg
    16801 ctttgcctgg tttccggcac cagaagcggt gccggaaagc tggctggagt gcgatcttcc
    16861 tgaggccgat actgtcgtcg tcccctcaaa ctggcagatg cacggttacg atgcgcccat
    16921 ctacaccaac gtgacctatc ccattacggt caatccgccg tttgttccca cggagaatcc
    16981 gacgggttgt tactcgctca catttaatgt tgatgaaagc tggctacagg aaggccagac
    17041 gcgaattatt tttgatggcg ttaactcggc gtttcatctg tggtgcaacg gtcgctgggt
    17101 cggttacggt caggacagtc gtttgccgtc tgaatttgac ctgagcgcat ttttacgcgc
    17161 cggagaaaac cgcctcgcgg tgatggtgct gcgctggagt gacggcagtt atctggaaga
    17221 tcaggatatg tggcggatga gcggcatttt ccgtgacgtc tcgttgctgc ataaaccgac
    17281 tacacaaatc agcgatttcc atgttgccac tcactttaat gatgatttca gccgcgcggt
    17341 actggaggca gaagttcaga tgtacggcga gctgcgcgat gagctgcggg tgacggtttc
    17401 tttgtggcag ggtgaaacgc aggtcgccag cggcaccgcg cctttcggcg gtgaaattat
    17461 cgatgagcgt ggtggttatg ccgatcgcgt cacgctacgt ctgaacgtcg aaaacccggc
    17521 gctgtggagc gccgaaatcc cgaatctcta tcgtgcggtg gttgaactgc acaccgccga
    17581 cggcacgctg attgaagcag aagcctgcga tgtcggtttc cgcgaggtgc ggattgaaaa
    17641 tggtctgctg ctgctgaacg gcaagccgtt gctgattcga ggcgttaacc gtcacgagca
    17701 tcatcctctg catggtcagg tcatggatga gcagacgatg gtgcaggata tcctgctgat
    17761 gaagcagaac aactttaacg ccgtgcgctg ttcgcattat ccgaaccatc cgctgtggta
    17821 cacgctgtgc gaccgctacg gcctgtatgt ggtggatgaa gccaatattg aaacccacgg
    17881 catggtgcca atgaatcgtc tgaccgatga tccgcgctgg ctaccggcga tgagcgaacg
    17941 cgtaacgcga atggtgcagc gcgatcgtaa tcacccgagt gtgatcatct ggtcgctggg
    18001 gaatgaatca ggccacggcg ctaatcacga cgcgctgtat cgctggatca aatctgtcga
    18061 tccttcccgc ccggtgcagt atgaaggcgg cggagccgac accacggcca ccgatattat
    18121 ttgcccgatg tacgcgcgcg tggatgaaga ccagcccttc ccggctgtgc cgaaatggtc
    18181 catcaaaaaa tggctttcgc tacctggaga actgcgccca ctgatccttt gcgaatatgc
    18241 ccacgcaatg ggtaacagtc ttggcggttt cgctaaatac tggcaggcgt ttcgtcagta
    18301 tccccgttta cagggcggct tcgtctggga ctgggtggat cagtcgctga ttaaatatga
    18361 tgaaaacggc aacccgtggt tggcttacgg cggtgatttt ggcgatacgc cgaacgatcg
    18421 ccagttctgc atgaacggtc tggtctttgc cgaccgcacg ccgcatccgg cgctgacgga
    18481 agcaaaatac cagcagcagt ttttccagtt ccgtttatcc gggcaaacca tcgaagtgac
    18541 cagcgaatac ctgttccgtc atagcgataa cgagctcctg cactggatgg tggcgctgga
    18601 tggcaagccg ctggcaagcg gtgaagtgcc tctggatgtc gctccacaag gtaaacagtt
    18661 gattgaactg cctggactac cgcagccgga gagcgccgga caactctggc ttacggtaca
    18721 cgtagtgcaa ccgaacgcga ccgcatggtc agaagccgga cacatcagcg cctggcagca
    18781 gtggcgtctg gcggaaaacc tcagcgtgac actccccgcc gcgtcccacg ccatcccgca
    18841 tctgaccacc agcgaaatgg atttttgcat cgagctgggt aataagcgtt ggcaatttaa
    18901 ccgccagtca ggctttcttt cacagatgtg gattggcgat aaaaaacaac tgctgacgcc
    18961 gctgcgcgat cagttcaccc gcgcgccgct ggataacgac attggcgtaa gtgaagcgac
    19021 ccgcattgac ccgaacgcct gggtcgaacg ctggaaggtg gcgggccatt accaggccga
    19081 agcggcgttg ttgcagtgct cggcagatac acttgccgac gcggtgctga ttacgaccgc
    19141 tcacgcgtgg cagcatcagg ggaaaacctt atttatcagc cggaaaacct accggattga
    19201 tggtagtggt caaatggcga ttaccgttga tgttgaagta gcgagcgata caccgcatcc
    19261 ggctcggatt ggcctgacct gccagctggc acaggtagca gagcgggtaa actggctcgg
    19321 attagggccg caagaaaact atcccgaccg ccttactgcc gcctgttttg accgctggga
    19381 tctgccattg tcagacatgt ataccccgta cgtcttcccg agcgaaaacg gtctgcgctg
    19441 cgggacgcgc gaattgaatt atggcccaca ccagtggcgc ggcgacttcc agttcaatat
    19501 cagtcgctac agccaacaac aactgatgga aaccagccat cgccatctgc tgcacgcgga
    19561 agaaggcaca tggctgaata tcgacggttt ccatatgggg attggtggcg acgactcctg
    19621 gagcccgtca gtatcggcgg aattccagct gagcgccggt cgctaccatt accagttggt
    19681 ctggtgtcaa aaataataat aaccgggcag gccatgtctg cccgtatttc gcgtaaggaa
    19741 atccattatg tactatttaa aaaacacaaa cttttggatg ttcggtttat tctttttctt
    19801 ttactttttt atcatgggag cctacttccc gtttttcccg atttggctac atgacatcaa
    19861 ccatatcagc aaaagtgata cgggtattat ttttgccgct atttctctgt tctcgctatt
    19921 attccaaccg ctgtttggtc tgctttctga caaactcggg ctgcgcaaat acctgctgtg
    19981 gattattacc ggcatgttag tgatgtttgc gccgttcttt atttttatct tcgggccact
    20041 gttacaatac aacattttag taggatcgat tgttggtggt atttatctag gcttttgttt
    20101 taacgccggt gcgccagcag tagaggcatt tattgagaaa gtcagccgtc gcagtaattt
    20161 cgaatttggt cgcgcgcgga tgtttggctg tgttggctgg gcgctgtgtg cctcgattgt
    20221 cggcatcatg ttcaccatca ataatcagtt tgttttctgg ctgggttctg gctgtgcact
    20281 catcctcgcc gttttactct ttttcgccaa aacggatgcg ccctcttccg ccacggttgc
    20341 caatgcggta ggtgccaacc attcggcatt tagccttaag ctggcgctgg aactgttcag
    20401 acagccaaaa ctgtggtttt tgtcactgta tgttattggc gtttcctgca cctacgatgt
    20461 ttttgaccaa cagtttgcta atttctttac ttcgttcttt gctaccggtg aacagggtac
    20521 gcgggtattt ggctacgtaa cgacaatggg cgaattactt aacgcctcga ttatgttctt
    20581 tgcgccactg atcattaatc gcatcggtgg gaaaaacgcc ctgctgctgg ctggcactat
    20641 tatgtctgta cgtattattg gctcatcgtt cgccacctca gcgctggaag tggttattct
    20701 gaaaacgctg catatgtttg aagtaccgtt cctgctggtg ggctgcttta aatatattac
    20761 cagccagttt gaagtgcgtt tttcagcgac gatttatctg gtctgtttct gcttctttaa
    20821 gcaactggcg atgattttta tgtctgtact ggcgggtaat atgtatgaaa gcatcggttt
    20881 ccagggcgct tatctggtgc tgggtctggt ggcgctgggc ttcaccttaa tttccgtgtt
    20941 cacgcttagc ggccccggcc cgctttctct actgcgtcgt caggtgaatg aagtcgctta
    21001 agcaatcaat gtcggatgcg gcgcgagcgc cttatccgac caacatatca ggacggaatg
    21061 atcgcaatga acatgtcgat gacagaaaga ataaaagcag gcaagctatt taccgatatg
    21121 tgcgaaggct taccggaaaa aagacttcgt gggaaaacgt taatgtatga gtttaatcac
    21181 tcgcatccat cagaagttga aaaaagagaa agcctgatta aagaaatgtt tgccacggta
    21241 ggggaaaacg cctggataga accacctgtc tatttctctt acggttccaa catccatata
    21301 ggccgcaatt tttatgcaaa tttcaattta accattgtcg acgactacac ggtaacgatc
    21361 ggtgataacg tattgattgc acccaatgtt actctttccg ttacgggaca ccctgtacac
    21421 catgaattga gaaaaaacgg tgagatgtac tcttttccga taacgattgg caataacgtc
    21481 tggatcggaa gtcatgtggt tattaatcca ggcgtcacca tcggggataa ttctgttatt
    21541 ggcgcgggta gtgtcgtcat aaaagacatt ccacctaacg tcgtggcggc tggcgttcct
    21601 tgtcgggtta ttcgcgaaat aaacgaccgg gataagcaat attatttcaa agattataaa
    21661 gttgaatcgt cagtttaaat tataaaaatt gcctgatacg ctgcgcttat caggcctaca
    21721 agttcagcga tctacattag ccgtatccgg catgaacaaa gcgcaggaac aagcgtcgca
    21781 tcatgcctct ttgacccaca gctgcggaaa acgtgctggt gcaaaacgca gggttataat
    21841 catcagccca acgacgcaca gcgcatgaaa tgcccagtcc atcaggtaat tgccgctgat
    21901 actacgcagc acgccagaaa accacggggc aagcccggcg atgataaaac cgattccctg
    21961 cataaacgcc accagcttgc cagcaatagc cggttgcaca gagtgatcga gcgccagcag
    22021 caaacagagc ggaaacgcgc cgcccagacc taacccacac accatcgccc acaagaccgg
    22081 caattgcagc ggcaaccaga taaagccgca gaaccccacc agttgtaaca ccagcgccag
    22141 cattaacagt ttgcgccgat cctgatggcg agccatagca ggcatcagca aagctcctgc
    22201 ggcttgccca agcgtcatca atgccagtaa ggaaccgctg tactgcgcgc tggcaccaat
    22261 ctcaatatag aaagcgggta accaggcaat caggctggcg taaccgccgt taatcagacc
    22321 gaagtaaaca cccagcgtcc acgcgcgggg agtgaatacc acgcgaaccg gagtggttgt
    22381 tgtcttgtgg gaagaggcga cctcgcgggc gctttgccac caccaggcaa agagcgcaac
    22441 aacggcaggc agcgcccacc aggcgagtgt ttgataccag gattcgctat gttgaactaa
    22501 ccagggcgtt atggcggcac caagtccacc gccgcccatc agagccgcag accacagccc
    22561 catcacctgt ggcgtgcgtt gctgaaaccg ccgtttaatc actgaaggca tcaccgcctg
    22621 aatgataccg atccccaccc caccaagcag tgcgctgcta agcagcagca cactttgggg
    22681 gtaaagctca cgcatcaatg caccgacggc aatcagcaac agactgatgg cgacgctgcg
    22741 acgttcgctg acatgctgat gaagccagct tccggccagc gccagcccgc ccatggtgac
    22801 caccggcaga gcggtcaaca gggcagccac gctaaagctc attccgctcg cctggcgcaa
    22861 ttgcggtagc agtggaccga cggaggtgag cagtggtcgc atattaagac caatcagcac
    22921 cagaaccagc agcatcgtga acgtcttttg atgattgcgc atggctgtca gaacggcttg
    22981 gtcggcagat atttaccatc taaggtaatg accgcacgtt cgccaccttc cgggtccgcc
    23041 actttcttaa cgtcgagttt gaagttaatc gcgctgataa tgccatcgcc aaacttctca
    23101 tgaaccaacg ctttcagggt tgtgccgtac acctgcaaca tttcatagaa acgatacatc
    23161 gttgggtcgg ttggaatacg gtcatcaatg cagccacgca gtggaatcat ctgcaacagt
    23221 agaatggcgt cttcgtcgag atccagcttc gccccgacca ggcgggcggc gtcggcagga
    23281 agcgcttgct gccccagcaa agccgcggtt acgaaggctt ctgccagacc ggtaccgtcg
    23341 gcaatctcgg caaatgagag atctttttta gctttgctga gcaaaatggc atcggcaaga
    23401 tcaagacgaa tattgcggtt aatttgtgac tgaatcatgg tggatctcct gatggtttaa
    23461 aaataaggtt acgctgcggt cggttggcgt agcggtatgg cacaaacgcg aggattagcg
    23521 gccagtggca caaactggcg ggttgcgccg tcaaaagctg cgatgctgcc gctttcaatg
    23581 tcgtagaccc agccgtgcag ggcgatccgc ccctcttcga gcgccaggcg caccgatgga
    23641 tgagtttgca aattagccaa ctgagcaatg acgttttcac gtaccatcgc cgcagctttt
    23701 gacggtaaat cggaatgcgg gcgcgcctca ttaacgacgc gggctgaatc ggcataacgc
    23761 agccagtggg agacggcagg catatggtcc atgcactgac agctggcaat ggcggtcatc
    23821 gcgccacagt tggaatgacc acaaatcaca atgtcagata cccgaagcgc agcgacggca
    23881 tactccaccg aagcagaaac gccaccgggt tccggcccgt aggaagggac gatattgccc
    23941 gcgttgcgaa taacgaacag atcgccaggc tcacgttgcg tcaccagctc agggaccaga
    24001 cggctgtcgg agcaggagat aaaaagtgtg cgcgggcttt gctgtgtcgc cagctgttta
    24061 aacaaggctt cccgcttcgg aaatgcctcg cgctggaatt taaggaatcc atcaataatc
    24121 tctttcaccg ttaacctctg tctgtctctg gaatgagagg cagactactc gccgattgtc
    24181 ataaggtaaa agtctcattt atgatgagtt ctattggatt tacttatagg ttggcgaatg
    24241 ctctctcgac atatcaacta ttttcttgcc gtggctgaac atggcagctt tacccgtgcc
    24301 gccagtgcgt tgcacgtctc ccagcctgcg ctttcccagc agattcgcca gttagaggag
    24361 agtttaggcg tgccgctgtt tgaccgtagc gggcgaacga ttcgtctcac tgatgcagga
    24421 gaagtctggc gacagtacgc cagccgggcg ttacaggaac tgggggcggg taaacgggcg
    24481 attcatgatg ttgccgatct gacgcgagga tcgctgcgta tcgccgtcac tcccaccttt
    24541 acaagctact ttatcggccc tttaatggcg gatttctatg cgcgctaccc cggcatcacg
    24601 ctccagctac aggaaatgtc gcaggagaaa atcgaagatc tgctttgtcg cgacgagctg
    24661 gacgttggga ttgccttcgc gcctgtgcat tcgccggagc tggaggcaat tcctttactg
    24721 acagaaagtt tagcgttggt ggtggcgaaa catcatccgc tagctgcctg tgaacaggtg
    24781 gcgttgagtc gcttgcatga tgaaaaactg gtcctgctca gcgcggaatt tgccaccaga
    24841 gagcaaattg accactactg cgagaaagcg gggctacatc cacaggtggt cattgaggcg
    24901 aactcaatta gcgcggttct ggagctgatt cgccgcactt ccctttccac attgttacca
    24961 gcagcgattg ccacacaaca tgacgggctt aaagcgattt ctcttgcccc gccactactg
    25021 gagagaacgg cggttttgtt gcggcggaaa aatagctggc agacagccgc cgcgaaggca
    25081 tttttgcaca tggcgttgga ggaatgtgcg gatgttggcg agaatgaatc acggtagcca
    25141 ctgacacagg tcagtggctc ttcaacacag aggaaattac cgtttgtaat cgatggcttc
    25201 tggctgctcc agatatacgg tggtttgtgc cggttgtgta ctggcaatca ccttgccgcc
    25261 acgtaccgaa taacgtaccg gaacctgacg gcgcagcgca tcaaatccat tttcagccgg
    25321 caggataatc aggtttgcgc tgtttccggc ggcaatgccg taatcctgca aattcaatgt
    25381 tctggcactg tggtgggtga ttaaattcag gccatcatta atctgcccgt agcccatcaa
    25441 ctggcaaaca tgcagcccca tatgcagcac ttgcagcata ttcgccgttc ccagcggata
    25501 ccacggatcg aagacatcat cgtgaccaaa gcagacgtta atgccggact ccagcatctc
    25561 tttaacgcgc gtgatgccgc gacgttttgg atacgtatcg aaacgtcctt gcagatgaat
    25621 attgaccagc gggttggcga caaagttaat accggacatt ttcagcaagc ggaacaggcg
    25681 tgaggtatac gccccgttat aggagtgcat tgccgtggtg tggctggcgg tgactcgcgc
    25741 gcccatgcct tcacggtgcg ccagggcagc aacggtttcg acaaagcgcg actgctcgtc
    25801 atcgatctca tcacagtgaa cgtcgatgag acggtcgtat ttttgcgcca gggcgaaggt
    25861 tttatgcagc gactccacgc cgtattcacg ggtaaattca aaatgcggaa tcgcccccac
    25921 tacatctgcc cctaagcgta acgcctcttc cagcaacgct tcaccgttgg gatacgacaa
    25981 aatcccttcc tgagggaagg cgacaatttg cagatcaatc cacggcgcga cttcctgctt
    26041 cacttccagc attgctttca gcgcagttag cgttgcatcc gaaacatcga catgggtacg
    26101 cacatgctga atgccgttgg caatctgcca tttcagcgtt tgccaggcgc gttgtttcac
    26161 atcgtcatgg gttaataacg ctttgcgctc ggcccagcgt tcaatgcctt caaacagcgt
    26221 gccggactga ttccagttcg gttgtccggc ggtttgcgtg gtgtccaggt gaatatgcgg
    26281 ctccacaaac ggcggtataa ctaaaccttg ttcggcatcc aggctgtttt cagttatggg
    26341 catcacgccg gattgcgcat caatggcgct gatttttccg tcctgcagat gaatctgcca
    26401 cagcccctct ttgcctggta accgggcgtt aataattgtt tgtaaagcgt tattcgacac
    26461 tgttaacctc cacatgcgtc attgctgctg tcgttttacg attcaaaatc gggttaagga
    26521 tcagatagct cagcgcgcca cctaataccg cgttgaccgg aacaattccc ggtaaccagt
    26581 ggcctgcggc aatccccagc gcgaccgcca gaatcgccac ccaattgaca ctcatcatac
    26641 gcgtggtcgc aaagtgctca tagcggcgac ggttcatcag atagtcggcg atgatcacgc
    26701 cccctaccgg aggaatagct gccgaaagga aggtcaacca gccgacaaaa ttgttataca
    26761 gccataatgc gcagaccgta ccgataatac cgttgattac cgaaagggtt ttgctcgaca
    26821 taccggtaat gttggcgaaa cctaaacccg acgcatagag tgcgttatcg ttggtggtcc
    26881 agatattcag ccccagcacc acaatcgcag gcagcagcag gccctgagca atcatcacat
    26941 cagagatatc cgccatgccc agtgccgcag cgcccgctgc accgaaaata aacatcaacg
    27001 agttgccgag gaaaaaggcc accatcgcca ccagcaccgc cagtttggca ttgcgaccaa
    27061 accggacaaa gtcagcggtg agcgtacccg cactgataaa tgaccccaca accagcgcca
    27121 gcgcgacatt gaaatctaac ggttgtgcgg gaacgaccgc ttttaatgcg tccaggccgc
    27181 ccatgccgtt aacagccagc cacacggaat aaccgcccag gcaggcgata gccggaaccg
    27241 caatcaccga aagaaccgtc agcgccgaaa tgccaaaaaa gacggtgacg gtcatcagta
    27301 aaccggaaac ggcaatcagc aaattaatat ccagcccggt tgccttaccc accggaatgg
    27361 caaacatcgc cacaccgacg ccaaaccagc caacctgagt tccgcccagt agcagtgaag
    27421 gcagccatga gcctttaaca ccaaacgaga agcgagcaag aagatgagtg gtcaggccgg
    27481 tttttgcgcc aatgtaaccg agaaatgaag tgtaaatacc gaggagaaga ttaccgatga
    27541 gaactgcgag gaagaaatca tgatagctaa gaccggttcc gagagtgccg ccggtccaca
    27601 tactggcgga aaagaaggtt aatcccagca tgacgaacgt caatgccaat acccctttcc
    27661 gcgccgactg cgggactggc ccctggctaa agttgttatc ttgcgacacg aaattccccc
    27721 tttttgctgt ttgaaaccca aaaaatccgc cgcattctat tcatctgaag ataaaaagca
    27781 atcgttttcg tggggaaata tattttttat atgaatgagt gcaaaaaggt gggggaaaaa
    27841 ttatcggtgt aaaaacagtg ggtaggcata ataagacgcg gtaagcgtcg catcaggcat
    27901 cggcgcatgg tgtcggatgc gccacgcgac gcatccgaca ataccttact cttccatcgc
    27961 ctggcggatc tgatccaacg acgcaggatc atcaatggtc gtcagatccc caggatcgcg
    28021 tccttcgcaa atcgcctgga tcgtgcggcg cagcattttt ccggatcgcg tttttggcaa
    28081 ttgcgagaca aaccagacgt gcgccgggcg gccaaagttg ccaatctggc tgtccaccag
    28141 cgccataatc gccttctctt gcgagtgcgc cacatcacga tcttccagac tgtcgctctc
    28201 tttcggaatg acaaacgcca ccgccacctg ccctttcagc gcatctttca ccccaaccac
    28261 cgccacttcg gcaacgcccg gatggctgga gatactctct tcaatctcgc gcgtccccag
    28321 ccgatgcccg gcaacgttaa ttacatcgtc agtgcgcccg agaataaagt gataaccgtc
    28381 agcgtcacgg atgccccagt caaaggtggc gtacaccggg cgggaaaaca gcgaccagta
    28441 agtcttcaca aagcggccgt cgtcgcccca gatggtctga atacaccccg gcggcagcgg
    28501 cccttccacc accagcatcc ctttctcgtt gacgccacac ggttcgccgg tgacttcatt
    28561 aagcaactgc acgttatagc catacatcgg cacaccgggg cttcccagac gcgtcggcct
    28621 gtcgtccaga ccgcgagcaa tcgccataat cggccagccg gattcggtct gccagtagtt
    28681 gtcgatgacc ggcacatcca gcgtattgct cacccaactg gcggtcggct cgtccagcgg
    28741 ttctccagcc agatagagca cttccagcga cgagagatcg tgtttgcgaa tttcagcggt
    28801 agggaatttt ttcagcacgc gaatggcggt cggcgctgag aacatccggc taacctgata
    28861 tttctcgacg attttccacc acacgccgca gtccggccag gtcggtaatc cttcgtaaac
    28921 gatagtcgcc atccccgcca gcagcggcgc gtagacgata tacgaatgcc ccaccaccca
    28981 gccgatatcc gaagcacaaa agaacacacc gcccgctttg ccgccaaaaa tggtgtccat
    29041 cgaggtcgcc agcgccaccg catatccgcc gacgtcacgc tgcacgcctt taggtttgcc
    29101 ggtcgtgccg gaggtgtaga gaatgcagga ggtttcgttg gattccagcc acgccaccgg
    29161 tacccgcgcg ccgatgtgtt gatggcgcaa cgacgcgaaa tcgacatccc gcccgctgac
    29221 gcgtgccatt ttcgccagcc cgcgatccac cagcaaaaca tggcgtggct ggtgctgcgc
    29281 ctgacttatc gcatcgtcga gcaatttttt atagggaatg attttgccac cgcgcgctcc
    29341 ggcatcagcc gagacaatca gcaccggttt agcatcatca attcgcgccg ccacgctgtg
    29401 cgaggcaaat cccccaaaca ccaccgaatg aatagcgcca atgcgcgcgc aggccagcag
    29461 agtaatatgc gcttcggcaa tcatcggcat atacaccagc acccgatcgc cacgctgcac
    29521 gcccagcgag cgcagcattg acgccaccgc gtttacttcg tcatgaagct gacgaaaggt
    29581 aaaggtgcgc tcttcttctg tttccgaaga gacggcaatc agcgccagcg cctctggttg
    29641 tttctccagc cagcggtcga tagcgttgtg gcacaagttg gttcggcctt cacaaaacca
    29701 acgggcaaac ggcggattgc tgtgatcgag cgtttgcgta aagggcgtct gccagtcaat
    29761 acgccgggcc tgctcggccc agaactgctc cggttcgtta atcgaacgct gataaaattc
    29821 gctaaaagac ataatgctct cctgttgaac ttacgcctta ccgctgtttg cttaaatgac
    29881 gtacaggtcg agatactcat tgaccggcat ctgttccagg cgagttctgt cgagagaaac
    29941 ctccagaatg cgctgctgtt ggcgagtcgg gaactggcgc gcgagattga ttttgaattt
    30001 atcgaccagt ttcggaatac catcctgacg gcggcgagca tgaccaatgg ggtactccac
    30061 caccacttct tcaaatcgtg tgccgtcggt gaactcaagg gtaatggcat tggcgatggc
    30121 gcgtttttcc gggtcgtggt agtcagcggt aaatgccgga tcttcaaagc aattgatctt
    30181 ctcgcgcagg gcgtcgatac gtttatcttg cgccacgttg tcctcgtaat ctgccgccgt
    30241 taagcgcccg aacagcagcg ggatcgccac catgtactga atgcagtgat cgcggtctgc
    30301 cgggttattg agcggtcctt ttttgtcgat gatgcgaata caggcttcgt gggtgcgaat
    30361 ggtcactttt tcgatatccg ccgccgtttt gcctgctgcc tgcatctgtt catagagcgt
    30421 catcgctgct tcaactgccg tctgggagtg gaactccgcc gggaaggaga ttttgaacag
    30481 cacattttcc ataacgtagg aaccgtacgg gcgctggaag cggaacgatt cacctttaaa
    30541 ggagacgtcg tagaagcccc acaccggcgc agtcagggct gacgggtaac ccatttcgcc
    30601 cgttttcgcc atcagtgcca gacgtaccgc gcgggaagtg gcatcgcccg ccgcccagga
    30661 tttacgcgtg ccggtgttcg gcgcatggcg ataggtgcgc agcgactgac cgtccaccca
    30721 cgccagcgaa acggcgttga gaatttcctc gcgggtcagg ccgagcattt cggcgaccac
    30781 ggcggtggaa gccactttca ctaacagaac gtggtcgagg ccgacgcggt taaaggagtt
    30841 ttccagcgcg atgcagccct gaatttcatg ggctttgatc attgcggtca gcacctgttt
    30901 catggtcaac ggcgctttgc cgctggcgac cgcgttgcgc gaaagccagt ccgccgttgc
    30961 cagaatgccg ccgaggttgt cggaaggatg gccccactcc gccgccagcc aggtatcgtt
    31021 gaaatcgagc cagcggatca tcgcgccgat gttaaatgcc gcctggacgg ggtcgagctg
    31081 gaactgagtt ccggggacgc gcacgccgtt gggtacgaca gtgccgggga caattggccc
    31141 cagcagtttt ttacaggccg ggtattcgag agcttcaaga ccgcagccga gcgtgtcgag
    31201 caggcagtaa tgggcggtgt cgtaggctac tttggagctg atttcgtagt tcatcacgta
    31261 atcgacgata tcaacgattt cacgatcaaa ttccgggcgg atgttgttga tttgagctga
    31321 cattgggtac gtttccttat tgttattcgt agaggtttac tggcgcttat ccagcgcgac
    31381 aaactggcgg tcttccggtc caacataatt ggcggaagga cggataattt tgttgtcctg
    31441 acgttgttcg ataatgtgcg ccgcccagcc ggtgacgcgg gcgataacaa acagtggtgt
    31501 gaacatctcg gtgggaacgc ccatcatgtt gtaggaaaca gcggagaacc agtcgagatt
    31561 ggggaacatc tttttgctct cccacatcac tgtttccagg cgatcggcga tgttatacat
    31621 cttcagcgaa ccgccttcct gcgagagctg cttcgccaca cgtttaatca cctggtggcg
    31681 cgggtcagcg atggtgtaaa ccggatgacc aaaaccaatg accacttctt tgttttccac
    31741 gcgcttgcgg atatctgctt cggcttcgtc cggcgtttcg tagcgttgct ggatctccag
    31801 cgacacttca ttcgccccgc cgtgttttgg cccgcgcagt gcgccaatcg cgccaataat
    31861 cgcggaatac atatcagagc cggtgcccgc aatcacccga ctggtaaagg tggaggcgtt
    31921 aaactcgtgt tcggcgtaca gcaccagcga gatatgcatc gccttttccc agctttgcga
    31981 tggcttttcg ccgtgcagca gatgcaggaa gtgaccgccg atggagtcgt catcggtttc
    32041 cggctggatg cgttcgccgt tgtgactgta gtgataccaa taaaggagaa tcgagctaag
    32101 tgatgccagc agtttgtcgg caatatcccg cgcgccagag acagtgtgcc cctctttttc
    32161 tggcagtgtg cagccgagcg cggaaacgcc ggtgcgcatg acatccatcg ggtgcgacgc
    32221 cgccggtaag gcttccagca cggtacgcac attagctggt aaaccacgca gggctttcag
    32281 tttcgttttg taagcggcga gttcgtcacg ggtcggcagt ttgccgtgga tcagcaggtg
    32341 cgccacttct tcaaattcgc aatgttccgc cagatcaaga atatcgtagc cacggtaatg
    32401 caggtcattg ccacttttac ccacggtgca gagcgccgta ttgcccgccg gaacgccaga
    32461 aagtgctacc gattttttcg gtttaatgac atgggtactg ttttgcagga tcgttgtgtc
    32521 gctcatattg tcctcgtcat ttgtagggtc gagatatttt tcgttgtgtt ttatttcacc
    32581 tggctacggg caaacaggtc gtcgagcttc tcttcgtact ggtagtagtt gatgctttcg
    32641 tacagctcgt tgcgggtttg catggtatcg atgacgcttt tctgcgtgcc ttcctgacgc
    32701 aggacgttgt agacatgttc agcggcgcgg ttcatggcgc ggaacgctga aagcgggtac
    32761 agcgccattg cgacatgggc gctgcgtaat tcgtcggtgg taaacagcgg tgttgcgcca
    32821 aattcggtaa tgttggcgag gattggcacc tgcaccgcat cggcaaactg gcggtacatg
    32881 gcgagttcgg taatcgcctc cgggaacaac atctcggcac ccgcttcaac ataggcctgc
    32941 gcacgctcga tcgccgcatc cagcccctct accgccagag catcggtgcg cgccatgatc
    33001 acaaaatcag gatcggtttt cgcatccacc gccgcgcgga tccgatccac catctcttct
    33061 ttcgagacga tcgctttatt cggacgatga ccgcagcgtt tcgcaccaac ctgatcttca
    33121 atatgcaatc ctgccgcacc ggctttaatc atcgatttca cggtgcgcgc cacgttaaag
    33181 gccgaagaac caaaaccgat atccgcatcc accagcagcg gcagcgaaca aacgtcggtg
    33241 atacggcgaa tgtcggtcag cacatcatca agggtagaaa taccgagatc gggcagcccc
    33301 agcgaacctg ccgccacgcc accgccagaa agataaattg cctgatatcc ggcacgctgc
    33361 gccaacagcg catgattagc gttgatggtg ccaacaatct gcaatggatt ttctttagtc
    33421 agtgcagcgc gaaacgcttt acctggagag tgtagagaca tagcccatcc tttgttatca
    33481 acttgttatt tgcgttgata aagacaaagc aaggggtgtg ccacaattgc cttaataaaa
    33541 ttaaatgttt aatttcaatt tgttagagat aaagtcatga actaatccgc aaatatgcgt
    33601 ttcagttaac gtttcaggca atgtttcacc gcgtttcatt gcaacaatta tgaaacaaga
    33661 ctaaacccaa tattcggttt cttaactttg cggtgcgcta tggcacatcc accacggctt
    33721 aatgacgaca aaccggttat ctggacggta tctgtaacgc gcctgttcga gctgtttcgc
    33781 gatatcagcc tcgagtttga tcacctggcg aacattaccc ctattcagct tggctttgaa
    33841 aaagcagtga cctacatccg caagaaactg gcaaacgaac gctgtgacgc catcatcgcg
    33901 gctggctcta acggcgcgta cctgaaaagc cgcctgtcag tgccagttat tttgattaaa
    33961 ccgagcggct acgatgtgtt acaggcactg gcaaaagccg gaaaactcac ctcttctatc
    34021 ggcgttgtca cctatcagga aaccattcca gcgctggtgg cgtttcaaaa aacctttaat
    34081 ttgcgcctcg atcaacgtag ctacattacc gaagaagacg cacgcgggca gattaacgag
    34141 ctaaaagcta acggcaccga agcggtggtc ggcgcggggc tgattaccga tctggcagaa
    34201 gaagccggaa tgaccggaat ttttatctat tccgccgcta ccgtgcgcca ggcgttcagc
    34261 gatgcgctgg atatgacgcg catgtcgtta cgccataaca ctcacgatgc cacccgcaac
    34321 gccctgagaa ctcgttacgt gctgggcgat atgctcggtc aatcaccaca gatggaacaa
    34381 gtacggcaga ctattttgct gtatgcccgc tccagtgcag cggtgttgat tgagggggaa
    34441 acggggacgg gcaaagagct ggcggcccag gcgattcatc gggaatattt tgcccgccac
    34501 gatgcgcgac agggcaaaaa gtcgcatccg tttgttgcag tcaactgcgg ggcgattgcc
    34561 gaatcgctgc tggaagcaga actgtttggc tatgaggaag gggcgtttac cggctcgcga
    34621 cgcggcggtc gcgccgggct gtttgaaatc gcccacggag gtacgctgtt tctcgatgag
    34681 attggcgaaa tgccgctgcc gttgcagacc cggctgctgc gggtgctgga agaaaaagag
    34741 gtcacccgcg tcggcgggca tcagcctgtt ccggtggatg tgcgggtcat tagcgccact
    34801 cactgcaatc tggaagaaga tatgcggcaa gggcagtttc gccgtgacct gttttatcgg
    34861 ctgagtattt tgcgtctgca attgccacca ctgcgcgagc gggtggcgga tattctgcca
    34921 ctggcggaaa gctttttgaa agtgtctctg gcggcgctct ccgccccgtt ttctgccgca
    34981 ttacgccagg gattacaggc aagcgaaacc gtgctggtgc actacgactg gccgggcaat
    35041 attcgtgaac tgcgcaatat gatggagcga ctggcgctat ttttaagtgt ggaaccgacg
    35101 ccggatttaa cgccgcaatt tttgcagctg ctactgccgg aactggcgcg cgagtcggcg
    35161 aaaactcccg ctccacgctt actgacacca caacaggcac tggagaaatt taatggcgat
    35221 aaaacagcag cggcgaatta tttaggcatc agccggacga cgttctggcg gcggctgaaa
    35281 agctgaactg ccgaatgcag cgcgaacgct ttatccggca taaatttcaa tagatgatga
    35341 tcaccgataa atttacgcat cggggatgtt tacatagggt tcagaattac ttcttcttat
    35401 aaatatttgc cgtgccgtgg atcttattgt cagtttgacc agaggtcagt accaacacat
    35461 cagccccttt ttcatccgct tttttgatca aatcctcttt cgcatctgcg gtcgacattt
    35521 cattactggt tgaaatatca cctatttttt catactgcga ttcaactttt tcaaattccg
    35581 ctttggtcat caattcagcg gcatagacat tggtaacggc aaacgctaac gcaccgacta
    35641 acattttaga gattattttc atattacggc tccagagttg ttatcacact atcacccacc
    35701 cacattattg ggttgattaa taattagttc agtcagggca taaaagccag taaccggaaa
    35761 taagacactt tgtgatctct ttcgcacccg attatttttg gtagaaatat gatgaagtta
    35821 cttcacttat ttatggatga aatcactatg gatcctttgc acgccgttta cctgaccgta
    35881 ggactgttcg tgattacttt ttttaatccg ggagccaatc tctttgtggt agtacaaacc
    35941 agcctggctt ccggtcgacg cgcaggtgtg ctgaccgggc tgggggtggc gctgggcgat
    36001 gcattttatt ccgggttggg tttgtttggt cttgcaacac taattacgca gtgtgaggag
    36061 attttttcgc ttatcagaat cgtcggcggc gcttatctct tatggtttgc gtggtgcagc
    36121 atgcgccgcc agtcaacacc gcaaatgagc acactacaac aaccgattag cgccccctgg
    36181 tatgtctttt ttcgccgcgg attaattacc gatctctcta acccgcaaac cgttttattt
    36241 tttattagta ttttctcagt aacattaaat gccgaaacac caacatgggc acgtttaatg
    36301 gcctgggcgg ggattgtgct cgcatcaatt atctggcgag tttttcttag tcaggcgttt
    36361 tctttgcccg ctgtgcgtcg tgcttatggg cgtatgcaac gcgttgccag tcgggttatt
    36421 ggtgcaatta ttggtgtatt cgcgctacgc ctgatttacg aaggggtgac gcagcggtga
    36481 gcagataatt tactctctac gtaatcaacc tgatttgccg aatcccggcc atcggcgatg
    36541 atagcccccg taatgcgtgg tccttatttc cgataagttt acttgagtct ttagcttccc
    36601 atttcagccc actctcccct gtgtgggctt ttttcattgg tctgccccgt cctgaatagc
    36661 caaacaatgg caatgttcca ctttgcaggg atgataataa ggggatctga ttcagaagag
    36721 ttttgaaaag ttggaccgcc atcgaggcct cgaaccccgt accatacaac aatcctggtt
    36781 gtcgtctgct cttcctgatg agctaatggc ggtttttgat atgagcctta cagcatattt
    36841 tctgtcaggc ttgagtgcga tgcgtaaggt acagaaaaga ccccacacaa acatgatgga
    36901 attatgattt ttttcatatg aatgtcaacc cacacattca caaaacatct gcatgagatc
    36961 attttttata caccgcatag ctgcgaaacc actgctggtg cttttttaag cgaagcgtcg
    37021 ccgatcacaa caaaatatcg gcgaaaaagg cggtggaatg ccatttggca tacggatata
    37081 cagatgaaat gattacctgc tttgcgattc actctctggt ggaataacaa cttgcaggtg
    37141 gaaccctttc tgaactaaag agtgtagcgg attttaacgt gcttatttac aggataatat
    37201 ctgtcaccta attcctgcac tctattcgat atccattcat ttaatcgtgc gtcatctctg
    37261 tatgttttta cgtccagaac agagagcaat aacatcacca gtgattcagg aaaaacaggg
    37321 tggatatttt ttaagtgtaa taataatcca tgcgcaagcg cctgcttaat gggcgcgtct
    37381 gtctccggaa tagacgacat ttcgcgaagc catttttcca cacgcataca ctctttccct
    37441 ttagggaaaa ttctcagcaa aggcatatgg tgttcaagaa gaatacattt gcaatctgtt
    37501 cgcactgaat cgataaactg cactaatttc ttaagcccgg taaagcgtcc agcctgcaca
    37561 tttgctttaa tatcaagaaa cgcatcatcc tggtcatata cccaaactgt ccctttttga
    37621 ttttcaagta tgcgaaaaac aaacttaacc gggtgatcag ggtaatccat ccagtcataa
    37681 aatccaggga aatcattaaa ctgcacattt atggtgagtg cgttatcgtc taaccactca
    37741 cagtctcgta cggcagccat gagatgaatg agtttgtcgt catcgactaa atcatcacga
    37801 caatcataag gataatcata atattgttta atcaaaacct tgaatatatc gacacaggaa
    37861 accagggagc ttttgatatc ctctggtaac tgattgtttt taaccgtatt aagtatgctt
    37921 tgttgcgtat atggcatcaa attattgtgc ggagctttta atgatatcat cgcgatctct
    37981 cttaaataaa aataaacgtc gcagataata aagctctcat taaaccaggc actatcagaa
    38041 atcgctcata actaacgtga gaagtattgt gtactggagg gagttaattt aacaatttga
    38101 atttacgtta taggttttac tgctactttg atattatttc gctctcctta actaaaaagt
    38161 taagtggaga gcgaagttaa tatgttaaac cacagggtat ttattaattt tttcagtctg
    38221 ttagtgtgcg attatcgata acaaaacgat atttcacatc accacgcagc attcgctcat
    38281 aggcttcatt aatttgatcg gcccgaatca tctctatatc agccacgatg ccatgttcgg
    38341 cgcaaaaatc gagcatctcc tgagtttctg gaatgccgcc aatcatagaa ccggctatcg
    38401 cacggcgttt catgatcagg ttgaaaactt ccggcgattt atgcggtgtc gcaggcgcac
    38461 caaccagcgt catggtgcca tcacgcttca gcaaggtggt aaaatcgtcg agattatgtg
    38521 gcgcagctac tgtattcaaa atgaaatcga aactcttcag atgagccgcc atctcatcgg
    38581 cattgcgtga gttaacaact tcatcggccc ccagggcttt tgccgcttcg cgttttgcct
    38641 cagaagtggt aaatgccacc acatgcgccc ccatcgcgtg ggccagcttg atccccatat
    38701 gtcccagacc gccgatgccg accacgccca cttttttacc cggcccggcc tgccagtgac
    38761 gtagcggcga atacgtggtg atccctgcac acaacaaagg agccaccgcc gccagctgct
    38821 cttgcgggtg acgaatacgc agaacatatc gctcatgaac gacgatctgt tgtgagtagc
    38881 cgcccagagt atggcccggt tcgtccggcg tcggcgagtt ataggtgccg gtcatgtgat
    38941 cacagtagtt ttccagcccg tcttcacact cttcgcaatg tttacaactg tcgacaatgc
    39001 agccgacacc gaccagatcg cccggcgcat gtttttctac ctgatcacca acggctacca
    39061 cacgccccac aatttcatga cccggtacgc aggggtaaac cgtccccgcc cactcggaac
    39121 ggacctggtg gagatcggaa tggcagacgc cacagtaagc gatttcgatt ttgacatcat
    39181 tcggtcccgg ttcacgccgt gtgatatcca tcggttcaag tggttgttta gcggaatatg
    39241 caccaacagc tttgatcttc attgtgttta ctcctgatta gctatgtgta tttggcgacg
    39301 cctgatatgt catcgcggca aaacgcgtcc attgaatata gccaatattt aaaccacccg
    39361 atccagcccc aacatgccgc gaacctgaat gaaacagagc agcaacgttc cccataaggc
    39421 catcgtcagg taggggctta taccgagaat attgaagccg ctttcaataa tttgcagaag
    39481 aaacagcgcc agcaccatac caattatccg cccgctgccg ccgtccggat taaccccacc
    39541 gagtactgcc gcgaggattg acaccagcaa gtacgattcg ccataagagg ccttagccga
    39601 gttgagtttc gacatcatca aaaatgccgc taccgcacaa agcaaggcgg aaatgacata
    39661 aacccaaatc agcacccgac gagtgttaat gccggagtaa agtgttgctc gttcgttaga
    39721 cccaatcagg taaatggctt taccgagcgg cgttttctcc agcaatatcc atagccccag
    39781 tgccactgcg gcaaacaacc acatcggtag cggaataccg aaccattgcg catgattcaa
    39841 ccacagcacc catgagggat aattggcaat ggcgctacca cctgtcacca gaatatttat
    39901 ccctttgagc aacgtcatca tcccaagcgt tgcaagaatt ggcgacactc gaataccagc
    39961 aatcaatacg ccgttacata aaccgattat caccgccgcg ccagcgcccg ccagtaacgt
    40021 agcgacaacc gtagcaatac ccggtggata ctgagtcgcc acccacgcca tcaccagtga
    40081 acaggcgtta gcagtggcta taattgacaa gttaatgcca ccgcaaagca tggtcaccgc
    40141 catagccaac gccagaatgc ccagcacggg catttgcgaa gcgacggact ggaaattact
    40201 tatcgaccag aaaatctccg gcatagtaat gctgaacgcg gcaacagtta gcaccagcag
    40261 gccgatcaag taaaactcaa cgttattacg ccacgatttt ttcatagcag actccggttc
    40321 tgatgctgac tccacgccgt ggcactaatg ctggcaacga tgatgatgcc ggtgatcaat
    40381 gtttgccagt aagacgagac tcccaataaa tttagcccgt tttgcatcac tgccaacaac
    40441 accacgccga gcaaagtacc ggttaacgtg ccgcgcccgc cgagcaaact agtgccgcca
    40501 agcaccaccg cagccagtac tgtcagctca taacccagaa gagaatcggg ggcgacagtc
    40561 atcaccgtcc acgactgcac tacacccgca gcgccagaca tcaatcccat atagccatag
    40621 acgaaaagtt gcagtttcag cacgctaaag ccgatgcgac tggctgattc gcggttcccg
    40681 ccaagggcat aaattttgcg ccctacactg gtgaaattca tgataaacgc tgttagcagc
    40741 accaccgtaa tcatggcgat cagcggcaga ccaaggccat agtcatagcc atcagcatcg
    40801 gtgtacttga acaacataac cccctgctca aaccacggcg gaaagtcgta cagccacaca
    40861 cctttactca accataacag caggccatag aaaatattca gcgtcgagat agtgatgatg
    40921 atagaaggca cccgtaggcg attaaccagt aaggcgttaa ttaagccaag taaaatgccg
    40981 atgcagcccg ccagtgcaaa cgcgacagcg aagttgccac caattttttg cagcaacagc
    41041 accatgccgt attgcgcaat gatggtcatt gctggaaacg aaatatcaat tccaccggaa
    41101 atcaacacca caaacaaacc acaggcgaga atagtcaaca tggcatagtt attggcgaga
    41161 tcgtacaaat taccgaatgt cagaaactcg tcgctgcgcc aggcaaggcc aacaaacagc
    41221 accacaatca gtaatgccag ccagaattca tggcgttttt tcagttcagc catttaccac
    41281 ctccgcaatc ctggcctgag aactgctgtc aggcaggaag ctatgggtga tctgaccttt
    41341 ttgcattacc aaaatccggt ggctttgata ccacgcttct tcaatttcat cgcagatcat
    41401 caataccgca atgccatgag ccgccagatc gctgataatg ccgtatattc ctgctttgtt
    41461 ggcgatatca acaccgactg tcgggctatc gagaatcaac agtcgtggcc caatcgccag
    41521 ccatttggcg atcgatactc gctgcgcgtt accaccagaa agcgtattca ccggaagatg
    41581 aggatcagag actttgatgg tcaatgcctt gattagcctg tccaccaggt cacgaacttt
    41641 agtttcactc agaaagccga agcgatcttt taccttgtga aaaacagtgc taatgatgtt
    41701 gtcttcaata gattgcgcca tcaccaaacc gcgcgacatg cgatcttccg aaacataacc
    41761 aataccgtgg cggatagcgt cctggttact atgcagtgta accggctggc cgttgatgag
    41821 gatctcgcca gcatccggtc gggtcatacc aaacagactc agacataatt ccgtgcgccc
    41881 cgcaccaagc aggccaacaa tcgataccac ttcgcccgct tccacccgca agttaatatt
    41941 tagatattcc ccatgacgac ttaaattacg cacctccagc accggggtgc tggattttcc
    42001 ctgccacaac tctcgcacct gatattcaaa ctcctggccg gtcatcagga aaccgagttg
    42061 ttttgtggtc atctctgcag ccggaaaagt cccgaccagc tcaccatctt tcagcactga
    42121 aatacggtcg gaaacttcca tcacttcttc cagacgatga ctgacgaaga ccacgcagat
    42181 cccgcgttca cgcaattgat gcaccacctg taataaccct tgcacttcct gatgggtcag
    42241 cgaagcggtt ggttcatcca tcacgatcaa ccgtgcgtcc tgcgccagtg cacggcaaat
    42301 agccaccagc tgacagcggg caattgaaag ctcagaaacg agtgtatcca gtggcaatgt
    42361 gacgttaata ctggtcattg ccgcctgcgc cacctcacgc agacgacggc ggttaacaaa
    42421 cagaccgtgg tgatagtgat tcacggcgat attctcccag acactcaggt taggaaataa
    42481 agagaggtcc tgataaatca cctgaatccc ctgcgccacc gaagcggcgg gtgtcagctt
    42541 tgaccagttt ttcccaccaa gcgtaatttc cgctccctca tccgggcgat aaacaccgga
    42601 cataatttta atcaacgtcg atttaccaca gccgttttgc ccggcaaggc agtgcacttc
    42661 acccgacata aagtcgagag aaacatcgcg cagcgctcgc gtggcatgaa acgttttgtt
    42721 gatatgacga agggaaagga aagtttccat aacatcccct ggcaataaga atcggggctt
    42781 tcgccccgaa gaaatggatt aataaagtga gtcgatattg tctttgttga ccagtaatac
    42841 cttatggaaa cggataattc gcttatccat atctacgtcg gccttaccca gattctgcat
    42901 ttctaatcca ggtttgatct cttcaccctt cagcaacgtg ctggcgacgg ctgcgagtgc
    42961 gtaacctgca gaggccggat cgtaagtaat cccttcggtg atatcaccac ttttaatcag
    43021 tgatgccgcc tgtgaaggga tcatcatgcc atagactgcg actttatttt tcgcccgttt
    43081 ctctttcacc gcacgtcccg cgccaatcgg accgtttgaa ccaaaggaga caaccgcttt
    43141 caagtcagga taggttttca tcaggtccag tgtggtacga cgtgagtcat ccacactctc
    43201 ggcaaccggc atgcggcggg taacttcatg catatccggg taatgctctt tctggtattt
    43261 caccagcaag tcagcccata agttatgctg cggcacggtc aaactaccca cgtaaatcac
    43321 atagccgccc ttgcccccca tgcgtttcgc catatgctca acatattcag cggcaaattt
    43381 ttcgttatca atgatttcaa tatcccagtt agcacttggc tgaccggggg attcgttggt
    43441 cagaaccaca attccggcat ctcgcgcttt tttgaatacc ggttccagca cgttggcatc
    43501 gtttggcacg atagtaattg cattaacctt acgggcgatt aaatcctcaa taattttaac
    43561 ttgttgcgga gcatcagtac ttgaaggccc cacctgtgag gcattaacac caaaggcgtt
    43621 acccgcctca accacacctt cgcccatgcg attaaaccac ggcataccat cgactttaga
    43681 gatattcacc acgacttttt ccgctgcctg gagcggcgca gaaattagcg cagcgcctaa
    43741 taacagcgaa gacaccatat tgataacaaa acgtttattc atcatttcag cctcattgca
    43801 gggtagtcag gaagtgttcg cccaaattag cgcgctggag agaataagaa ttttcgaata
    43861 tttttatgca gaataaacag ccctatttca ggcagctatt aaaaatatgg ttataaatat
    43921 ggacaaaacg ggcagcaaca ataagtgtga cattcatcac gtaaaaaata gcaaaataaa
    43981 caaaattagc gatattttat gtgtgtgagt ttatttcgcg tagataaata gttatctaca
    44041 caacgtcaat aagggcatat tcttcaaata taacgtccat ttctggtgaa tagcttcctt
    44101 ctgcctggaa aaaacgacgg tgttcattac gccaatattc aagactgagg tcaccttcac
    44161 cttccttacg ggcaagctcc acggtgacat cagaaaagcg cagtaaatgc aggccaatca
    44221 ctctgataac acatacaggc tcaccacggc tattttctac aatcttatac tcaccaatca
    44281 tcggaaatgc gttgtcttca atacatcccg ccagcgaacc acaggaagct gttttaacac
    44341 cagtcgcaat caacgttgcg aggtgatcgg ccaacgctgc tgaatcgcca aaagtacaaa
    44401 aggaagcatg gggatatttt tgtgagaatt tttcttttat ggtcatggca atatttttgc
    44461 gattacggaa aaacaaatca catcttaatt actgttggta accatcagca agagtatcat
    44521 tggtttttcg atactgaatc ttttttatcc gaagcaggtc acatttatgg cctgataaat
    44581 acctttgtta aaactcactt ttgtgtattt ctctcaaata atcccctgga aattatgccg
    44641 cgagattata aagttcagga tcattcatta gcaaaccatt cccgccccac tccctggggc
    44701 ttaaatctct tacaattcac cgttgcaggc gtttcaaatg cgcatcaacc tgccacactc
    44761 ccccacacca gttgcccttt atggaacgtt gcggttctcg gcgagatacg cgccaccgcc
    44821 tcggcggaac aggaggcgtc caccagcaca aagctggcat catcctgcgc ttttggccat
    44881 acacgctcgc ctttttcatt cagcggcaat acatcgccag tggctagaaa cagcgaacgg
    44941 gagaggttct gttcgttagg acgaatatag agctgcgcgt agagattggc tttttccagc
    45001 atgtcgccca gaccataagg cgaccagtgg tcgataacgc tgtcagtgcc agtcatcact
    45061 tttacgcctt tgtcgtgcaa ctgtttgagc ggcatatgca gcgtgccaat cggcaccgtc
    45121 gaggcgatag aaatttgctg cgccgccatc cgattcgcca gcgcatcgac ctgttgttcg
    45181 ttgagcgtag ccagcgcaaa ggcgtggctg atggtcaact tacctttcag ttgcggcgtt
    45241 ttctctaccg tttcaaccat ataattgatg gctgccacgc ccgacggagt ggtttcgtgc
    45301 aggtgaatat cgacaccttt gtcgtagtcc agcgcaatct gaaacatggt gtcgagggat
    45361 ttttccatcg cgccatcaac actggtcggg tccagcccgc cgacgtaatg cgcacccgcc
    45421 tgcatcgctt cgcgcattaa gggttccgat ttcgacagca gcaaaccgtg ctgcgggaag
    45481 gcgacgattt cacactcgaa gcccgcctga cgtcgcgcca gcaccgcctg caaattctgc
    45541 agatttttca ggccggaaac cggttcgata ttgcagtggc tgcgggcaat ggtggtgcct
    45601 ttcgactgca atagatcgat cagtttttcc gcccgctcct gcgtatacgg ttgtaactcc
    45661 ggcagcattt tctgctcgag tttgatcatg tcctggatag tggtgcctgc cggacgattg
    45721 agcgagcgcc acggcccgcc gtagaaggtt ttgtcgagat gaatatgcat gtcgcgagtg
    45781 gtgggtagca tcaacttacc gccagcgtca tagtgcggca gcgtggcgtc cggatgctgc
    45841 ttgttctcgc gcagggcgac aattttgccg tcctgaatct ccacggtctg gcgcgccgtg
    45901 cgggtctgca ccgccacacc gttttcgtag tcaaaaccgg tttccagcag cacgttatcg
    45961 agatagtaat gcgggtcagt gattttcatg gtgttgttcg cttcgcagtt tagggtgcca
    46021 gctaccgccg catgggcgag cggcacagag gtaccaaaca gcgcggcggc ggtgaccatc
    46081 ttaccgctct ggctcagaaa ttcacggcgg ctattgcttt ctttcatcct acgtccttac
    46141 gttttaataa tatgggtgcc cgtttcaccg cgcagcgccg caggcaggca ttccggcgtg
    46201 gtgataatca cttctttgcc gccctgctcc aggaacgtca ggctggcgat gatttttggc
    46261 aacatgctgc cgggcggaaa atgcccttcc tgcatatagc gagtcatggt ggcaatatcc
    46321 acccgatcca gcgcctgctg ctgcggttta ccaaagtgga tacagacttt ttcgacgccg
    46381 gtggtgatca ccagaatgtc ggcgtgaatt tcacgggcca gcagcgcggt agagagatct
    46441 ttgtcaataa ccgcgtccac gctttggtaa tcccccgctt cagtacgcac taccggaatt
    46501 ccaccgccgc ccgcgccaat tacgacaaaa ccttgttgga tcagcgcctt aatggcgggt
    46561 gcttcgacaa tacgtttcgg ttccggcgag gcgaccacgc ggcgatagcc ccgtccggca
    46621 tcttcaacaa aacaccagtc agggtttgcc ttttgtagtt tgtcacgctg gctttcactg
    46681 aagaatgcac caatgggctt ggtgggatgg gcaaaacctg gatcgttttt atccacttcc
    46741 acctgagtta ccacggtgac ggcttttttc tcgccgtgac gcgccagccg gttattcagc
    46801 gcctgttgga tcagatagcc gatgccgccc tgcgtatctg ccacacagtt cgccagcggc
    46861 gttaagggca gcccttcgcg ctcgtgggca atctccgcac ggcgtaaatc cagcccgacc
    46921 tgcggcccgt taccgtgggt cagcacaatg tcgtaatcgg aagccagcat ttccagcacc
    46981 gtatcggcca cggctttcac cgcctccgcc tgatgctcaa tcgactggct ggcgttatct
    47041 ttgataatgc tgttgccacc aatggcaacg accacaagct ctttcatgtt gttatgtccg
    47101 ctacagaggg tgattaggtt atgaccaacg ccagactgcc tgatgcgcta cgcttatcag
    47161 gcctacaatt ctcgggccat ccgtaggccg gataaggcgt tcacaccgca tccggcataa
    47221 acatgtaagt cagacgccgt aacgttcgca ccagccgaga atggctttct cgaagcaggc
    47281 gaatggtgga tgcacaatgc ccgcgccaat catgccgacg cccgcatctt tatgggcgat
    47341 ggcggtgttg atcaccggca gaatgccgct gctacccacg cgggtgatgt cgattgccga
    47401 cggcacgccc ataaaaccga gcagcggaat ggtgacgttg gggttttcgc caagggtgat
    47461 ttcgcgcatc tgacgggaga aatcgatagc ctcttccacc gtgccgccca ccagtgcgac
    47521 gattgcaggc gcggtcgcca tggcaaaccc gccaataccg taggtttctg tgatagcgct
    47581 gtcgccgata tccagccccg aatcttccgg cttataacca gcaaacatcg ggccgatgac
    47641 ctgctgcgct gggccggtaa accactgccc cggcaggccg ctgacccgca ggccgaactc
    47701 gacgccgtta cgcgccatgg tggtgaccac ggtgctgtat tcgatgccgt gcgccgcatc
    47761 catcgccgct ttacacatcg ccatccacgt cgggccggag aagtagtcgc tgctggcgac
    47821 aaactcgaac acttcgcgct gttgctcgac ggaatagcct gcctgaatga tccccggcgt
    47881 cagtgcctga atcagcagcg tcgtcccggc gttattgcgg ttatggcact catcgcccat
    47941 atgcagcgcc tgcgccagca ttaagcgcag atcgatctca ccgataattt tcatcgcgtc
    48001 gcgcagcatt ggcccctgca catcgcgcat ccagttgagg cggtcgatca cgctctgatc
    48061 gttggcaccc atacgcaaaa tcttcgccat ctgctcgctc atattggtat aagcgatgtt
    48121 gccgtaggtt ttgtttttca cgatgtgcat aaacatcgag gccgaggtaa cgcccgccat
    48181 cgatcccacg cagtcgtgtt cgtggcacgg cgagaaggtg atctccccgg aggccgccag
    48241 ttcagtcgcc tcatcgagat ctttcgccag cccttcgaac accaacgccc cggtgaccgc
    48301 gcctttcatc gcgccgcaca ttttttccca ggtgatcggc ggcccggcgt gaagaatggt
    48361 tttcggcgtc atgcccggca ccacgttaat cgcctgatca aaaccaatca gcaccggatg
    48421 cgactggata atgcgctcca gcgcctgctg gttagcggcg gcgattttgt ctgccagcgg
    48481 cgaatcggca atgttatcca gcgcctgcac cacctgcata ttgccctgcc ccggcggcgt
    48541 ccagtcgagt tgagtcactt ctacatgctg ctttttcagg tcatcgctaa acatggcgat
    48601 accgacgtta ataacgttca acggttggct aaacagtgac tggctcatca ggcttcctcc
    48661 cctttgcaga taaattcacg cgccagcaat ccggtattgg tgctgctgct cgccagaatc
    48721 actccggcat caagcagcat ctggctttgt tgttctaatg atggcgtatc gagatcggtg
    48781 cccagcacat aggcgagaat gatcaactcg cgtccttcgg cggcggcgat cgctttcgct
    48841 tctttgatcg cctcgatggt ggagccgacc ggatcttcat gcgatccaaa tccgagcaca
    48901 aaatccatca cgatcaccgc cacttctgga tcgcgcgctt cttcgatcaa gcgactgatg
    48961 cggttggtgg ggtcaatcat tggatgcggc ttgccgttgg tgaagtcgtc atcgccaaag
    49021 tcgaggaagg tgtgtttgat gctgcggttg atatcttgca ggcggaattc aggatcgggc
    49081 tgaatgttgc tgtagacatc gccatgtttt tccatcaccg cgaacatggt ttcgtcgcac
    49141 agcgtgccgc cgcagaacag gccacgtatg tatttctgct gcggttgcag acgcgcacgc
    49201 acatcagcaa tcaacggctg gttaagcgta tgcaggtcga gattttcctg tttcacgccg
    49261 gagagcatca ccgcttttag cgccgcctct ttgctgccgc gggcaaactg tagcccctgc
    49321 tcatccaccg gcgtttcaac gcgaccgagg aagcagacca ccaccggctt gcggcaggcg
    49381 cgcgcgcgtt ccagcacttt acgggccacc gcaggcgcgg gcggtttgga gataagcaca
    49441 atgatttcag tttgcggatc gttttccagc atcccgatgg cgtcgagcat catcaggccg
    49501 ccgattttct cgctcaggtc gcgcccgccg gtgccaatca gttgtgaaac gccgccacca
    49561 aattcatgaa tgcggacgct cagttcctgg ctgccggtgc cagatgcgcc aacaataccg
    49621 atgttgccac gacgcacggc gttgccaaaa cagagcgccg cgccgttaat aatcgccgta
    49681 ccgcagtctg gccccatcat cagcagccct ttttcgtggg ccagttgctt gagcgccagt
    49741 tcatcttcaa ctgagacgtt atcggaaaac agcatcacgt tgagatcgtt ttgcagcgcc
    49801 tgacgcgctt cgcgagcggc aaacagaccg ttgaccgaaa tcaccgccag gttactttcc
    49861 gggatatgct ttttggcgct ggcaatagtg gcgtaacgcg cctcgtgcga gccgctttgc
    49921 gctttgctat tgaacagttc ttcaatctcc gccagcaact gctcattgtc cgcacccgat
    49981 ttaccattga tgacaatcat caggtcgccg tttttcgcct gttccagctc cggcgtcagc
    50041 agtcctaaat ttttcagcac acctttgttc atttcggtcg ccatcgccac aaatgcctgc
    50101 tcgacgccgt cgagtttatt tgcacgcgtg gagatagaca tcagcgagac agaatcaaaa
    50161 taggtattcg gtttaatgac tattttaact gacataattc cctccgtagg tttggctcag
    50221 cgcacaacca tcggccatgc catacagcat gtcgcagccg gaactggagc caatatgttt
    50281 aattttttct attgcctgag ttgaattccc agggacgcca taaataatat cgtgaataaa
    50341 atgatgaata ttttcccggc agcgttgttg taatgcggct tccagcgtta tggcacttaa
    50401 taatgtggta ttatttctgc cgcgttgcag accgcgataa aattcctctt tgtatttttc
    50461 cgccggatgc ccggaaataa ataaaataag taccagtccg gtcagataat catcggctga
    50521 tggcgtaagg ccaatcccta accccatcat actggcgacc gctgcggcga tattttgttt
    50581 ttcgtttact gcctgaataa ctgcccgtcg tttaatatgt agttctttat ttaacgcctg
    50641 ataaaacgga ttatcgccgc gataattaaa cagggtttca ttttccccca ggtgctgatg
    50701 aataatgtcg tgccactgtt gccaggcgat aaggtgaaaa ttcacagcgg tcatttgcaa
    50761 ggttggggac agccaacgcc gacaacgact catctctata tgaagatgtt gaccaaccgt
    50821 aataccttga tcgtcaaact gaaccttatc accatgccgg aacagatcat caaagtgagt
    50881 gagtgccaac cgacaactgt ttggcgcatt gtcgtactct tcacaaagca gcgtcagcaa
    50941 ctgctggcga gccgggagtg cgatatttac cgctctggca aagacctgtt caacctgtcc
    51001 ttgcccccgc tgcgccagaa aatccgcatc cgcagttagc gcccacacac accgtctttc
    51061 tggtgtgttg atagcaagcc tcccggttta tgcacctgcg gcaatcagta actgcgcaat
    51121 ctcttcaaag ccccgttccc gcgccagttc cagtggcgtt ttgccatatt tatcggtcag
    51181 atgcgggctg gcaccgtgtt ccagcaataa ctgcacaatc gcctgctgtt taataccacc
    51241 atcattaagc acaatcgctt ccagtagcgg cgtccagcct acatggttgg tctggttaac
    51301 gttaatctcc gtatgcgcca aaagctcttt tacaatactt aaatggcctt tttcacaggc
    51361 aggcgtcagg ccgacaccgc caaaacgggt tacgcaatta agatcgggtt tagccggtaa
    51421 aataattcgt agtagcgtta aatcatcgtt cagacagcta attaaaaaag gatttaaaca
    51481 ggtatgatct tgcttattaa tatccgctcc ggcatcaatt aatgcctgaa cgcaagcata
    51541 ttgctgatat aaacttgcca gcgtaattgc cgttttcccc tgacgatcgc aggtattaat
    51601 atcgacaccc agcgcaaggc aggtttttac tttatcgata tcaccctgtt gtgcagccaa
    51661 taaatagtcg gcaggtagat tttttatact cattcacatt cccctggttt ttgtggctgt
    51721 tttcgatgaa ttgagaatag caacgataat ctgataaaag aacccgctta aatttaattc
    51781 gctgtatttc gcctttttgt tgaatgatgt tcaacaatct tttcgcagtg tgcggtagtg
    51841 caatatttgt ttctttgacc cgataccctt tcactcaatc aggttttatt tctctatagt
    51901 ctgcacatgt aagagtagct ttcgtccatg tctaaccaga ggggaacaag atgaacggac
    51961 tcacggcaac gggtgtcacc gtcggtattt gtgcagggct ttggcagtta gtgtcttcac
    52021 atgtcgggct ctctcaggga tgggaattat taggaaccat tggcttcgtc gccttttgca
    52081 gtttttatgc cgcaggcggc ggtaaatcgg ggtttatcag aagtctggcg gttaattatt
    52141 ccgggatggt gtgggcattt ttcgccgcgc tggctgccgg ttggctggcc tctgtaagtg
    52201 gactgtccgc gttctgggcg agcgtaatta ctaccgtacc cttctcggcg gtagtggtct
    52261 ggcaagggcg tttctggtta ctgtccttta ttcccggtgg ctttctcggc atgacgctgt
    52321 tttttgccag cgggatgaac tggacggtga cgttactggg ttttctggcg ggtaactgcg
    52381 tggggataat ttcagaatat ggtggacaaa aattaagcga agcgacgact aaacgcgacg
    52441 ggtattaaaa gttattcaaa aatgattatc tatctttaac cgatacctct acagtcatag
    52501 ctggagaaat tcatagtaga taatggcgag aatggtttaa tgaactcaat ttttaccgaa
    52561 gagaatctgt tggcatttac taccgctgcg cgttttggca gcttcagtaa agccgcagac
    52621 gagttgggtt taaccacttc cgccattagc tacaccatca agcgtatgga gacggggctg
    52681 gatgtggtgc tgttcactcg caacacccgc agcattgagt taaccgagtc cgggcgttat
    52741 tttttccgca aagctaccga cctgctgaat gattttcacg ccatcaaacg cagtatcgat
    52801 actatttcgc agggcataga agcacgggtg cgcatttgta ttaatcagct gctttatacg
    52861 cccaaacaca ccgcgcgctt attacaggtg ctgaaaaagc agtttcctac ctgccagatt
    52921 accgtgacga ccgaagtgta taacggcgtc tgggatgcga ttattaataa tcaggccaat
    52981 atcgccatcg gcgcacccga tacactactg gacggcggcg gtattgatta cactgaaatt
    53041 ggcgcgattc gctgggcttt tgctatcgcc ccggatcacc cgttagcctt tatgccggaa
    53101 cccatcgccg aaagccaact gcgtctctac cctaatatta tggtggagga caccgcgcat
    53161 acgattaata aaaaagtggg ctggttgctg cacgggcagg agtcaattct ggtgccagat
    53221 ttcaacacca aatgtcagtg ccagatttta ggtgaaggaa ttggtttttt gccggattac
    53281 atggtccgtg aggcgatgac gcaatccctg ctggttaccc gacaaatcca taatccgcgc
    53341 caggattcgc gcatgttact ggcgactcag cattctgcta cgggtcaggt gacgcagtgg
    53401 attaaaaaac aatttgcgcc aaatggcata ttaacgggga tctatcagga tttactgcat
    53461 cgggagaatt aatcgctgcc aacctcccga tgcgctgtga atagcggttt acatcaacca
    53521 cctgctttca ttacccattc agagataaat ttattacccg gtactggcgg agagtacaaa
    53581 tagccctgca aaaagtgaac gcctttaccg atcattaaat ccgcctgctc ctgggtttct
    53641 accccttccg ccacgatact cagaccaggc ttacgcgcta gttcgacaat attgtccaca
    53701 atatgaccgg agatttcgtc gacactcgcc atttgcacaa atgacttatc gatcttaata
    53761 aaatcgaccg ggaacgcctg caagtaacga taggtcgcat aacccgtacc aaagtcatcc
    53821 agcgcaaagg taatgttgtg ctgatgaagg ctgtcaaata tcgctctggc ttctggcgtt
    53881 accggaatag gattacgttc cgttagctcg agaaccagct tgattttatc gttacctaat
    53941 ttcttaacca ggttcagaca ctctttttca aatcccgctg ccaaaaaaca acccgccgag
    54001 acgttgatgc caatatggaa attgtccggc agcaaatgtt ttaccggcat cagaatatcc
    54061 gcagtctgtt tcatcagttg gcgggtcatt atgacaataa gaccggatga ctccgccaga
    54121 ggaataaact gatccggtgg gataattccc gtttgtggat gttcccagcg gacaagtacc
    54181 tcacagcccg tcagtacccc agtctgcgcg cagaaaaccg gttggatcca cggtttgaat
    54241 tcgtggtttt ccaacgccag actgatggct tcaggcgtga cgatatggtg acaacggtta
    54301 tcagggatat aaaaattatt tttatttccc gtgccactga tgacttgcgg atgatattga
    54361 aaaaagatat cccgccagaa ggtaatatca ctctggatgc ctagtttttc atacagctgc
    54421 ttcttttgat gtgaaattgt ctttgcactg cgatttctgt actgtgagat ttctgtaacc
    54481 gacattccct ccattagcag cttgagtaaa agccgttctt tttcggacac gataccaggc
    54541 aacgtcaaat tcaccgttgc cccgaactct tccaaaaaaa cactcaaatc atgcgaagcc
    54601 attgaacaca ccttgattaa atcttgtgcg ccagctaaat ctgcgagtct tcactctgac
    54661 tgataaagct ggctgcaaga aaatgacaca gagagccgaa ttatctcccg ttcggctctc
    54721 tctcctttta ctcattattc agatcagaat tgccacttaa tgccaaccat tgcagaggtg
    54781 tcattatatc ccctatcggc aacctgaacg cccacattcc cccagacatt caggttggca
    54841 tttagctgtc cttccacccc ggtttttatc tcagcaatat ttcgggctcc atcctgagtg
    54901 acggacacgc catccatact ggtgctgaaa tccttactgt tatgcagcca gttcacttct
    54961 acaaacggct ggaactcgcg ggatttaccg tcatccattt tatggtggct cttcagccag
    55021 gtttttacgc caagtcgggt ttgaacattg ccatcaccgt tgctatgaac gagggttccg
    55081 ttgctttcgc ggtgcttatc ggctttgact cccatccagg taacctgtgc ttgcggctga
    55141 acataccatt cattacgcgt tccctggctg ccattaaatt cagctaattt gtgtttgtat
    55201 ccagcttcca gtgaagcggt aaatcctttt gatttatagg attcactttg taagtcatcc
    55261 cctttcactg tgttatcaaa ccagctgtac tgcgcccaac tgtcgagata cgcgccatta
    55321 cgcgactcgt catcggcata ccaggtggca tagaggccgg tgctatatcc gttcacactc
    55381 gcttttgcac gataaccggt tcgcgaggaa atggttttgc tgtcgctgtt gccatatccc
    55441 gccatgaccc caacatgcca gctgtcgctg ccgttttggc tccactgcgc gacatcgcct
    55501 cccagttgca gaacatagcg attgctttgg gttttcagct ggccgctgcc atcacgccat
    55561 ttattacgac caccttcatg gcgcatccac atagtggttt gtttctgctc acccgtcacc
    55621 atgtcggtat agtacgtatt acccagacgc tcatgcagac gcgtggtgaa cattgtattc
    55681 gctgctgcaa ggttcgcaat gtagctaccc gcctccggtc gcaggtcatt atccacattc
    55741 agatccggac ccggcgtagg tgtcgggtta gggttcggct ctggattcgg gtttggctcc
    55801 ggattcggca tcgggtctgg ctccggctgc agttcaggag aatcactgcc gctggtcaga
    55861 taccagttac cactatttgc cccttgtcca cgcgcgagag tgtagtcata cgcccccgca
    55921 acgatacgac cagcctgaac aaattcgccc tcagacttac cgtctacatg gataagttcg
    55981 ataccgttaa gggttttcgc acctataccg ccagcgttat tcaccgtaac ggcagtcgtg
    56041 ccgctagtat cgccctcgac aaccaattta tcggttactg agtcatcgcc attcagtacc
    56101 gtattcatta ctagttgacc gttattaccg tggtagttcc ccttcaccac taacacattg
    56161 ccagcttgct gtcctgacat tccggtcatc agcgtaccgt tgttggtcag attgccgccc
    56221 agggtgtaat tcacagacgc agccgctctt ttttcagtgc tattattcaa cgccagggta
    56281 ccgttgttct caacgtttgc gctacccaat ccctgcgcat gacttaccag gacattagcc
    56341 gaattagcaa tgttcacatt cgccgtcagg ttgctgttat cgcccgcgat gtccagcgtg
    56401 ccgccctgaa tattcagctc tccgctcccc gttaacgaac cggttgaagt gcccccgttg
    56461 gtaaccgtca gactgccgcc atttaagctc agcagtgaat cggcgctgcc attgagcgtg
    56521 cccacggtct ggctgtgacc attcatatcc agttcagtct ctgccgccag acgcagttca
    56581 tgggtattac ccaacacgtt atcgttattc aacaaaagcg tcccactgcg cagatcggta
    56641 acaccggtat agtcgttgtc tttgttagaa agcgatacgg tctgaccttt ctggctgctg
    56701 aatgccaggt caccactgcc gctaatcttt gcgctgagat cggcggcatt ctcgctttta
    56761 ccgttagagc tcagcaccag agcatcgctg tcggtagcgt gtaaatcaag ctgggtcagg
    56821 ccgtaaccga tatacagacc gtcattgttt accccactcg tcagacgata gtcgtaagtg
    56881 ccgacggccg ctttttgccc attctgctga atatcacgtt gggcgctgct ggagaggatt
    56941 tgcccatttt tatcctgcaa ttgcagattg cccgcatcgc ccagaacttc cgcaccttgc
    57001 gcatcaacca acttaatggt gctgttacca tcatcaactt cagtaagcga taacgcggag
    57061 tcaatatcac gagatactga gcggacaacg tcactgtcag aaacctgaat cacaccctcg
    57121 ccgcgcaaat ccagcgtttt actaacgttg actgtccctt ctgtcatctg tgcacctgct
    57181 gccagggcac caaaatcaac cgttccgccg gagaatccca aagtgctaat ggagtgagcg
    57241 cccttaccca ctgttaccag gcttccctga cccgcagtga tcccgccttt ctgcagaaac
    57301 tcagcattct tttccagatt aaatgtcgtg ttctggaacg ccagtgaacc ctggaaccag
    57361 tctgtataag caaactcatc aaaggagaat tcgtgattcc ccatgtttat ttcaacaatg
    57421 cctctacctt caagatcgtt atcaaatacc caatctttat tggcattgat ttgcagtttg
    57481 ccatcaacat ccagttccgc acgtccgatg ttcttgtctt cagaaataac agctacagca
    57541 tcggaagcaa catcaatata tccgtagaat gcatagttat tgccggtcaa ctccaccgtc
    57601 ccactgtcga tacttattgt accgttgccg gagatcttat tggcaaaggt catgctatcc
    57661 tcagccttca ggtgtaattt cccgcggttg gtgatttctg cagagcctat attttgggtg
    57721 atccccaaag cgccattttt ctcaatcgtt actttgccgc taaaggcaga gttatccccg
    57781 gttaagtaag tcgtaccatt gagcgcattg atatagccca ggccctcgct gtcactgaca
    57841 atatccgcgg aaatagtcgc gtttttatcc gtgtggttta aggtgatttt cttctcggat
    57901 gtctttgccc acacaaactc aattttttcg gcatcaataa tccctgcagc cttcgcagca
    57961 cttccttcct gtgcacctaa cgctaactca gagttggtgc ttaaactaat agtcggcgca
    58021 gagattttac caccttccga aacagcaagt gttgtatcgg agttttgatc ataataaccc
    58081 aggctaattt tctcactggc attaacttca ccgccgttat taactgacag gtactgatta
    58141 ccaccgtaac tgccgtaaac gcccataaag aaggttttag aatttacctg gctgccttca
    58201 ccactgacat ttccctgcaa ataggtcaga cggctggtgc ccttaacatg gattttgccg
    58261 ccgttggaaa cattaaaata gccgcgatcg tgtctcatgc ctgagtttga ttcatacaaa
    58321 tcatcagcat ataactcgct gccagcattg gagacattca ggaaccccgt cccttttaac
    58381 aaaaagttaa gtgggccatt gattgttacc tttcctccgg taatatccaa cccaccacca
    58441 gaagcgagag tcagacgcgg acgggaagta tctgtcgcat tgattaccag attggcattg
    58501 tcagtcaccg taatacggta atcgatgctc tggttctctt tgccaaaatc aatagtttta
    58561 tcctggttta cgatgacatc atcggcgaat accagagatg aatataaact tatcgcgcta
    58621 attaaaacag cccgggactt ttttcctttt actctgctcc ccagctccga gcagacgctc
    58681 caacagttac gggacctgtt ccactttagc cgatatattt tattcatcac aatctccagc
    58741 aatacatcca aataaaacca agattgcata aacagcaacg cattaaatgc cattccggtt
    58801 actgttcatc gcatataaaa attcaaaaat tttgcatagc attgacaacc acatatctga
    58861 gtatgtagtt cagagggtaa taaaatagca agttactact gaaaacttat tttaagttaa
    58921 cactcttaac tttgtcatta cattcctccc ccagtctcta atacctgcgc attatatgta
    58981 tccaggaact caaatcaact caaaata
//
LOCUS       DAPGUL010000015        57964 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.015, whole genome shotgun sequence.
ACCESSION   DAPGUL010000015 DAPGUL010000000
VERSION     DAPGUL010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 57964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57964
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.015"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(30..509)
                     /gene="folK"
                     /locus_tag="RHX21_001067"
     CDS             complement(30..509)
                     /gene="folK"
                     /locus_tag="RHX21_001067"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HDV1986291.1"
                     /translation="MTVAYIAIGSNLASPLEQVNAALKALGDIPESHILAVSSFYRTP
                     PLGPQDQPDYLNAAVALETSLAPEELLNHTQRIELQQGRVRKAERWGPRTLDLDIMLF
                     GNEVINTERLTVPHYDMKNRGFMLWPLFEIAPELAFPDGETLREVVHTRAFDKLSKW"
     gene            complement(506..1924)
                     /gene="pcnB"
                     /locus_tag="RHX21_001068"
     CDS             complement(506..1924)
                     /gene="pcnB"
                     /locus_tag="RHX21_001068"
                     /EC_number="2.7.7.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polynucleotide adenylyltransferase PcnB"
                     /protein_id="HDV1986292.1"
                     /translation="MTLPRCTIFTRVANFCRKVLSREESEAEQAVARPQVTVIPREQH
                     AISRKDISENALKVMYRLNKAGYEAWLVGGGVRDLLLGKKPKDFDVTTNATPEQVRKL
                     FRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEGNVSDRTTSQRGQNGMLLRDNIFGS
                     IEEDAQRRDFTINSLYYSVADFTVRDYVGGMKDLKDGVIRLIGNPETRYREDPVRMLR
                     AVRFAAKLGMRISPETAEPIPRLATLLNDIPPARLFEESLKLLQAGYGYDTYKLLCEY
                     HLFQPLFPTITRYFTENGDSPMERIIEQVLKNTDTRIHNDMRVNPAFLFAAMFWYPLL
                     ETAQKIAQESGLTYHDAFALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQG
                     KRAWKLLEHPKFRAAYDLLALRAEVERNAELQRLVKWWGEFQVSAPPDQKGMLNELDE
                     EPSPRRRTRRPRKRAPRREGTA"
     gene            complement(1963..2889)
                     /gene="gluQRS"
                     /locus_tag="RHX21_001069"
     CDS             complement(1963..2889)
                     /gene="gluQRS"
                     /locus_tag="RHX21_001069"
                     /EC_number="6.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001432381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA glutamyl-Q(34) synthetase GluQRS"
                     /protein_id="HDV1986293.1"
                     /translation="MLPPYFLFKEMTDTQYIGRFAPSPSGELHFGSLIAALGSYLQAR
                     ARQGRWLVRIEDIDPPREVPGAAETILRQLEHYGLHWDGDVLWQSQRHHAYREALAWL
                     HEQGLSYYCTCTRARIQSIGGIYDGHCRVLHHGPDNAAVRIRQQHPVTQFTDQLRGII
                     HADEKLAREDFIIHRRDGLFAYNLAVVVDDHFQGVTEIVRGADLIEPTVRQISLYQLF
                     GWKVPDYIHLPLALNPQGAKLSKQNHAPALPKGDPRPVLIAALQFLGQQAEAHWQDFS
                     VEQILQSAVKNWRLTAVPESAIVNSTFSNASC"
     gene            complement(2926..3381)
                     /gene="dksA"
                     /locus_tag="RHX21_001070"
     CDS             complement(2926..3381)
                     /gene="dksA"
                     /locus_tag="RHX21_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002209354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-binding protein DksA"
                     /protein_id="HDV1986294.1"
                     /translation="MQEGQNRKTSSLSILAIAGVEPYQEKPGEEYMNEAQLAHFRRIL
                     EAWRNQLRDEVDRTVTHMQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKT
                     LKKVEDEDFGYCESCGVEIGIRRLEARPTADLCIDCKTLAEIREKQMAG"
     gene            complement(3559..4263)
                     /gene="sfsA"
                     /locus_tag="RHX21_001071"
     CDS             complement(3559..4263)
                     /gene="sfsA"
                     /locus_tag="RHX21_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HDV1986295.1"
                     /translation="MEFSPPLQRATLIQRYKRFLADVITPDGRELTLHCPNTGAMTGC
                     ATPGDTVWYSTSDNTKRKYPHTWELTQSQSGAFICVNTLWANRLTKEAILNESISELS
                     GYSSLKSEVKYGAERSRIDFMLQADSRPDCYIEVKSVTLAENEQGYFPDAVTERGQKH
                     LRELMSVAAEGQRAVIFFAVLHSAITRFSPARHIDEKYAQLLSEAQQRGVEILAYKAE
                     ISAEGMALKKSLPVTL"
     gene            complement(4278..4808)
                     /gene="thpR"
                     /locus_tag="RHX21_001072"
     CDS             complement(4278..4808)
                     /gene="thpR"
                     /locus_tag="RHX21_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414689.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2',3'-cyclic phosphodiesterase"
                     /protein_id="HDV1986296.1"
                     /translation="MSEPQRLFFAIDLPAEIREQIIHWRATHFPPEAGRPVAADNLHL
                     TLAFLGEVSAEKEKALSLLAGRIRQPGFTLTLDDAGQWLRSRVVWLGMRQPPRGLIQL
                     ANMLRSQAARSGCFQSNRPFHPHITLLRDASEAVTIPPPGFNWSYAVTEFTLYASSFA
                     RGRTRYTPLKRWALTQ"
     gene            4882..7311
                     /gene="hrpB"
                     /locus_tag="RHX21_001073"
     CDS             4882..7311
                     /gene="hrpB"
                     /locus_tag="RHX21_001073"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414690.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase HrpB"
                     /protein_id="HDV1986297.1"
                     /translation="MSSLPVAAVLSELLTALDCAPQVLLSAPTGAGKSTWLPLQLLAH
                     PGINGKIILLEPRRLAARNVAQRLAELLNEKPGDTVGYRMRAQNCVGPNTRLEVVTEG
                     VLTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVQQGLRDDLKLLIMSATLD
                     NDRLQQMLPEAPVVISEGRSFPVERHYLPLPAHQRFDEAVAVATAEMLRQESGSLLLF
                     LPGVGEIQRVQEQLASRIGSDVLLCPLYGALSLNDQRKAILPAPQGMRKVVLATNIAE
                     TSLTIEGIRLVVDCAQERVARFDPRTGLTRLITQRVSQASMTQRAGRAGRLEPGISLH
                     LIAKEQAERAAAQSEPEILQSDLSGLLMELLQWGCSDPAQMSWLDQPPTVNLLAAKRL
                     LQMLGALEGERLSAQGQKMAALGNDPRLAAMLVSAKNDDEAATAAKIAAILEEPPRMG
                     NSDLGVAFSRNQPAWQQRSQQLLKRLNVRGGEADSSLIAPLLAGAFADRIARRRGQDG
                     RYQLANGMGAMLDANDALSRHEWLIAPLLLQGSASPDARILLALPVDIDELVQRCPQL
                     VQQSDTVEWDDAQGTLKAWRRLQIGQLTVKVQPLAKPSEDELHQAMLNGIREKGLSVL
                     NWTAEAEQLRLRLLCAAKWLPEYDWPAVDDESLLATLETWLLPHMTGVHSLRGLKSLD
                     IYQALRGLLDWGMQQRLDSELPAHYTVPTGSRIAIRYHEDNPPALAVRMQEMFGEATN
                     PTIAQGRVPLVLELLSPAQRPLQITRDLSAFWKGAYREVQKEMKGRYPKHVWPDDPAN
                     TAPTRRTKKYS"
     gene            7507..10041
                     /gene="mrcB"
                     /locus_tag="RHX21_001074"
     CDS             7507..10041
                     /gene="mrcB"
                     /locus_tag="RHX21_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706097.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glycosyl
                     transferase/transpeptidase"
                     /protein_id="HDV1986298.1"
                     /translation="MAGNDREPIGRKGKPTRPVKQKVSRRRYEDDDDYDDYDDYEDEE
                     PMPRKGKGKGKGRKPRGKRGWLWLLLKLAIVFAVLIAIYGVYLDQKIRSRIDGKVWQL
                     PAAVYGRMVNLEPDMTISKNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMIRRPFD
                     FPDSKEGQVRARLTFDGDHLATIVNMENNRQFGFFRLDPRLITMISSPNGEQRLFVPR
                     SGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGASTLTQQLVKNL
                     FLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIRGFPLASLYY
                     FGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQQIIDQELYD
                     MLSARPLGVQPRGGVISPQPAFMQLVRQELQAKLGDKVKDLSGVKIFTTFDSVAQDAA
                     EKAAVEGIPALKKQRKLSDLETAIVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSI
                     GSLAKPATYLTALSQPKIYRLNTWIADAPIALRQPNGQVWSPQNDDRRYSESGRVMLV
                     DALTRSMNVPTVNLGMALGLPAVTETWIKLGVPKDQLHPVPAMLLGALNLTPIEVAQA
                     FQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLWTMQQVVQRGT
                     GRQLGAKYPNLHLAGKTGTTNNNVDTWFAGIDGSTVTITWVGRDNNQPTKLYGASGAM
                     SIYQRYLANQTPTPLNLVPPEDIADMGVDYDGNFVCSGGMRVLPVWTSDPQSLCQQSE
                     MQQQPSGNPFDQSSQPQQQPQQQPAQQEQKDSDGVAGWIKDMFGSN"
     gene            10261..12504
                     /gene="fhuA"
                     /locus_tag="RHX21_001075"
     CDS             10261..12504
                     /gene="fhuA"
                     /locus_tag="RHX21_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrichrome porin FhuA"
                     /protein_id="HDV1986299.1"
                     /translation="MARSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITV
                     TAAPAPQESAWGPAATIAARQSATGTKTDTPIQKVPQSISVVTAEEMALHQPKSVKEA
                     LSYTPGVSVGTRGASNTYDHLIIRGFAAEGQSQNNYLNGLKLQGNFYNDAVIDPYMLE
                     RAEIMRGPVSVLYGKSSPGGLLNMVSKRPTTEPLKEVQFKAGTDSLFQTGFDFSDSLD
                     DDGVYSYRLTGLARSANAQQKGSEEQRYAIAPAFTWRPDDKTNFTFLSYFQNEPETGY
                     YGWLPKEGTVEPLPNGKRLPTDFNEGAKNNTYSRNEKMVGYSFDHEFNDTFTVRQNLR
                     FAENKTSQNSVYGYGVCSDPANAYSKQCAALAPADKGHYLARKYVVDDEKLQNFSVDT
                     QLQSKFATGDIDHTLLTGVDFMRMRNDINAWFGYDDSVPLLNLYNPVNTDFDFNAKDP
                     ANSGPYRILNKQKQTGVYVQDQAQWDKVLVTLGGRYDWADQESLNRVAGTTDKRDDKQ
                     FTWRGGVNYLFDNGVTPYFSYSESFEPSSQVGKDGNIFAPSKGKQYEVGVKYVPEDRP
                     IVVTGAVYNLTKTNNLMADPEGSFFSVEGGEIRARGVEIEAKAALSASVNVVGSYTYT
                     DAEYTTDTTYKGNTPAQVPKHMASLWADYTFFDGPLSGLTLGTGGRYTGSSYGDPANS
                     FKVGSYTVVDALVRYDLARVGMAGSNVALHVNNLFDREYVASCFNTYGCFWGAERQVV
                     ATATFRF"
     gene            12555..13352
                     /gene="fhuC"
                     /locus_tag="RHX21_001076"
     CDS             12555..13352
                     /gene="fhuC"
                     /locus_tag="RHX21_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe3+-hydroxamate ABC transporter ATP-binding
                     protein FhuC"
                     /protein_id="HDV1986300.1"
                     /translation="MQEYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIG
                     HNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPPAEGMTV
                     RELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAM
                     LVAQDSCCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYL
                     VALRGGEMIAQGTPAEIMRGETLEMIYGIPMGILPHPAGAAPVSFVY"
     gene            13352..14242
                     /gene="fhuD"
                     /locus_tag="RHX21_001077"
     CDS             13352..14242
                     /gene="fhuD"
                     /locus_tag="RHX21_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-hydroxamate ABC transporter
                     substrate-binding protein FhuD"
                     /protein_id="HDV1986301.1"
                     /translation="MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWL
                     PVELLLALGIVPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVW
                     SAGYGPSSEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYED
                     FIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWG
                     STAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYG
                     ATLSAMHFVRVLDNAIGGKA"
     gene            14239..16221
                     /gene="fhuB"
                     /locus_tag="RHX21_001078"
     CDS             14239..16221
                     /gene="fhuB"
                     /locus_tag="RHX21_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-hydroxamate ABC transporter permease
                     FhuB"
                     /protein_id="HDV1986302.1"
                     /translation="MSKRIALFPALLLALLVIVATALTWMNFSQALPRSQWAQAAWSP
                     DINVIEQMIFHYSLLPRLAISLLVGAGLGLVGVLFQQVLRNPLAEPTTLGVATGAQLG
                     ITVTTLWAIPGAMASQFAALVGACVVGLIVFGVAWGKRLSPVTLILAGLVVSLYCGAI
                     NQLLVIFHHDQLQSMFLWSTGTLTQTDWGGVERLWPQLLGGVMLTLLLLRPLTLMGLD
                     DGVARNLGLALSLARLAALSLAIVISALLVNAVGIIGFIGLFAPLLAKMLGARRLLPR
                     LMLASLIGALILWLSDQIILWLTRVWMEVSTGSVTALIGAPLLLWLLPRLRSISAPDM
                     KVNDCVATERQHVLAFVLAGGVLLLMAVVVALSFGRDAHGWTWASGALLEDLMPWRWP
                     RIMAALFAGVMLAVAGCIIQRLTGNPMASPEVLGISSGAAFGVVLMLFLVPGNAFGWL
                     LPAGSLGAAVTLLIIMIAAGRGGFSPHRMLLAGMALSTAFTMLLMMLQASGDPRMAQV
                     LTWISGSTYNATDAQVWRTGIVMVILLAITPLCRRWLTILPLGGDTARAVGMALTPTR
                     IALLLLAACLTATATMTIGPLSFVGLMAPHIARMMGFRRTMPHIVISALVGGLLLVFA
                     DWCGRMVLFPFQIPAGLLSTFIGAPYFIYLLRKQSR"
     gene            complement(16256..17536)
                     /gene="hemL"
                     /locus_tag="RHX21_001079"
     CDS             complement(16256..17536)
                     /gene="hemL"
                     /locus_tag="RHX21_001079"
                     /EC_number="5.4.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="HDV1986303.1"
                     /translation="MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYL
                     YDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAQLVTEL
                     VPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTL
                     GQPNSPGVPADFAKHTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPE
                     FLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVVPDLTCLGKIIGGGMPVGAF
                     GGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGVHETLDELTTRLAEG
                     LLEAAEEAGIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHMMLDEGVY
                     LAPSAFEAGFMSVAHSMEDINNTIDAARRVFAKL"
     gene            17761..19182
                     /gene="clcA"
                     /locus_tag="RHX21_001080"
     CDS             17761..19182
                     /gene="clcA"
                     /locus_tag="RHX21_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H(+)/Cl(-) exchange transporter ClcA"
                     /protein_id="HDV1986304.1"
                     /translation="MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGT
                     LVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAP
                     EAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGR
                     MVLDIFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAV
                     FIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGM
                     QDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLV
                     FIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIA
                     GMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILA
                     RTLAKQEAEQLARSKAASASENT"
     gene            19206..19271
                     /locus_tag="RHX21_001081"
     CDS             19206..19271
                     /locus_tag="RHX21_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986305.1"
                     /translation="MAIIIGLEFAQLPMSFGAKYE"
     gene            19264..19608
                     /gene="erpA"
                     /locus_tag="RHX21_001082"
     CDS             19264..19608
                     /gene="erpA"
                     /locus_tag="RHX21_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster insertion protein ErpA"
                     /protein_id="HDV1986306.1"
                     /translation="MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSG
                     FQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNA
                     KSTCGCGSSFSI"
     gene            complement(19655..20278)
                     /locus_tag="RHX21_001083"
     CDS             complement(19655..20278)
                     /locus_tag="RHX21_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRIC cation channel family protein"
                     /protein_id="HDV1986307.1"
                     /translation="MLVYWLDIVGTAVFAISGVLLAGKLRMDPFGVLVLGVVTAVGGG
                     TIRDMALDHGPVFWVKDPTDLVVAMVTSMLTIVLVRQPRRLPKWMLPVLDAVGLAVFV
                     GIGVNKAFNAEAGPLIAVCMGVITGVGGGIIRDVLAREIPMILRTEIYATACIIGGIV
                     HATAYYTFSVPLETASMMGMVVTLLIRLAAIRWHLKLPTFALDENGR"
     gene            complement(20316..21116)
                     /gene="btuF"
                     /locus_tag="RHX21_001084"
     CDS             complement(20316..21116)
                     /gene="btuF"
                     /locus_tag="RHX21_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter substrate-binding
                     protein BtuF"
                     /protein_id="HDV1986308.1"
                     /translation="MAKSLFRALVALSFLAPLWLNAAPRVITLSPANTELAFAAGITP
                     VGVSSYSDYPPQAQKIEQVSTWQGMNLERIVALKPDLVIAWRGGNAERQVDQLASLGI
                     KVMWVDATSIEQIANALRQLAPWSPQPDKAEQAAQSLLDQYAQLKAQYADKPKKRVFL
                     QFGINPPFTSGKESIQNQVLEVCGGENIFKDSRVPWPQVSREQVLARSPQAIVITGGP
                     DQIPKIKQYWGEQLKIPVIPLTSDWFERASPRIILAAQQLCNALSQVD"
     gene            complement(21109..21807)
                     /gene="mtnN"
                     /locus_tag="RHX21_001085"
     CDS             complement(21109..21807)
                     /gene="mtnN"
                     /locus_tag="RHX21_001085"
                     /EC_number="3.2.2.16"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/S-adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HDV1986309.1"
                     /translation="MKIGIIGAMEEEVTLLRDKIENRQTISLGGCEIYTGQLNGTEVA
                     LLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADV
                     TAFGYEYGQLPGCPAGFKADDKLIAAAEACIAELNLNAVRGLIVSGDAFINGSVGLAK
                     IRHNFPQAIAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQS
                     SLMVESLVQKLAHG"
     gene            21891..23408
                     /gene="dgt"
                     /locus_tag="RHX21_001086"
     CDS             21891..23408
                     /gene="dgt"
                     /locus_tag="RHX21_001086"
                     /EC_number="3.1.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dGTPase"
                     /protein_id="HDV1986310.1"
                     /translation="MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPA
                     IRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDEL
                     TGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAAL
                     RLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWW
                     RGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVAD
                     LEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFM
                     YLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFS
                     HPDVEQLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTR
                     HRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ"
     gene            23538..24962
                     /gene="degP"
                     /locus_tag="RHX21_001087"
     CDS             23538..24962
                     /gene="degP"
                     /locus_tag="RHX21_001087"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine endoprotease DegP"
                     /protein_id="HDV1986311.1"
                     /translation="MKKTTLALSALALSLGLALSPLSATAAETSSATTAQQMPSLAPM
                     LEKVMPSVVSINVEGSTTVNTPRMPRNFQQFFGDDSPFCQEGSPFQSSPFCQGGQGGN
                     GGGQQQKFMALGSGVIIDADKGYVVTNNHVVDNATVIKVQLSDGRKFDAKMVGKDPRS
                     DIALIQIQNPKNLTAIKMADSDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLNA
                     ENYENFIQTDAAINRGNSGGALVNLNGELIGINTAILAPDGGNIGIGFAIPSNMVKNL
                     TSQMVEYGQVKRGELGIMGTELNSELAKAMKVDAQRGAFVSQVLPNSSAAKAGIKAGD
                     VITSLNGKPISSFAALRAQVGTMPVGSKLTLGLLRDGKQVNVNLELQQSSQNQVDSSS
                     IFNGIEGAEMSNKGKDQGVVVNNVKTGTPAAQIGLKKGDVIIGANQQAVKNIAELRKV
                     LDSKPSVLALNIQRGDSTIYLLMQ"
     gene            25117..26274
                     /gene="cdaR"
                     /locus_tag="RHX21_001088"
     CDS             25117..26274
                     /gene="cdaR"
                     /locus_tag="RHX21_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CdaR"
                     /protein_id="HDV1986312.1"
                     /translation="MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERI
                     GELHEGALLVLSQGRVVDIDDAVARHLHGVRQGINLPLRLEGEIVGVIGLTGEPENLR
                     KYGELVCMTAEMMLEQSRLMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDL
                     NQPRVVAIVEVDSGQLGVDSAMAELQQLQNALTTPERNNLVAIVSLTEMVVLKPALNS
                     FGRWDAEDHRKRVEQLITRMKEYGQLRFRVSLGNYFTGPGSIARSYRTAKTTMVVGKQ
                     RMPESRCYFYQDLMLPVLLDSLRGDWQANELARPLARLKAMDNNGLLRRTLAAWFRHN
                     VQPLATSKALFIHRNTLEYRLNRISELTGLDLGNFDDRLLLYVALQLDEER"
     gene            complement(26363..26749)
                     /locus_tag="RHX21_001089"
     CDS             complement(26363..26749)
                     /locus_tag="RHX21_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3461 family protein"
                     /protein_id="HDV1986313.1"
                     /translation="MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDKGEFFAK
                     SVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYIIDELDQICQRDRSEVDLKRKILD
                     DLRHLESVVTNKISEIEADLEKLTRK"
     gene            complement(27064..27888)
                     /gene="dapD"
                     /locus_tag="RHX21_001090"
     CDS             complement(27064..27888)
                     /gene="dapD"
                     /locus_tag="RHX21_001090"
                     /EC_number="2.3.1.117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase"
                     /protein_id="HDV1986314.1"
                     /translation="MQQLQNIIETAFERRAEITPANADTVTREAVNQVIALLDSGALR
                     VAEKIDGQWVTHQWLKKAVLLSFRINDNQVIEGAESRYFDKVPMKFADYDEARFQKEG
                     FRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
                     GVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYIGQSTRIYDRE
                     TGEIHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID"
     gene            complement(27919..30591)
                     /gene="glnD"
                     /locus_tag="RHX21_001091"
     CDS             complement(27919..30591)
                     /gene="glnD"
                     /locus_tag="RHX21_001091"
                     /EC_number="2.7.7.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     uridylyltransferase/uridylyl-removing protein GlnD"
                     /protein_id="HDV1986315.1"
                     /translation="MNTLPEQYANTALPTLPGQPQNPCVWPRDELTVGGIKAHIDTFQ
                     RWLGDAFDNGISAEQLIEARTEFIDQLLQRLWIEAGFSQIADLALVAVGGYGRGELHP
                     LSDIDLLILSRKKLPDDQAQKVGELLTLLWDVKLEVGHSVRTLEECMLEGLSDLTVAT
                     NLIESRLLIGDVALFLELQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPD
                     IKSSPGGLRDIHTLQWVARRHFGATSLDEMVGFGFLTSAERAELNECLHILWRIRFAL
                     HLVVSRYDNRLLFDRQLSVAQRLNYSGEGNEPVERMMKDYFRVTRRVSELNQMLLQLF
                     DEAILALPADEKPRPLDDEFQLRGTLIDLRDETLFMRQPEAILRMFYTMVRNSAITGI
                     YSTTLRQLRHARRHLQQPLCNIPEARKLFLSILRHPGAVRRGLLPMHRHSVLGAYMPQ
                     WSHIVGQMQFDLFHAYTVDEHTIRVMLKLESFASEETRQRHPLCVDVWPRLPSTELIF
                     IAALFHDIAKGRGGDHSILGAQDVVHFAELHGLNSRETQLVAWLVRQHLLMSVTAQRR
                     DIQDPEVIKQFAEEVQTENRLRYLVCLTVADICATNETLWNSWKQSLLRELYFATEKQ
                     LRRGMQNTPDMRERVRHHQLQALALLRMDNIDEEALHQIWSRCRANYFVRHSPNQLAW
                     HARHLLQHDLSKPLVLLSPQATRGGTEIFIWSPDRPYLFAAVCAELDRRNLSVHDAQI
                     FTTRDGMAMDTFIVLEPDGSPLSADRHEVIRFGLEQVLTQSSWQPPQPRRQPAKLRHF
                     TVETEVTFLPTHTDRKSFLELIALDQPGLLARVGKIFADLGISLHGARITTIGERVED
                     LFIIATADRRALNNELQQEVHQRLTEALNPNDKG"
     gene            complement(30653..31447)
                     /gene="map"
                     /locus_tag="RHX21_001092"
     CDS             complement(30653..31447)
                     /gene="map"
                     /locus_tag="RHX21_001092"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HDV1986316.1"
                     /translation="MAISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRI
                     CNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIK
                     DGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAE
                     GFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMK
                     DGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE"
     gene            31815..32540
                     /gene="rpsB"
                     /locus_tag="RHX21_001093"
     CDS             31815..32540
                     /gene="rpsB"
                     /locus_tag="RHX21_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HDV1986317.1"
                     /translation="MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLE
                     KTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLT
                     NWKTVRQSIKRLKDLETQSQDGTFEKLTKKEALMRTRELEKLENSLGGIKDMGGLPDA
                     LFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVA
                     ATVREGRSQDLASQAEESFVEAE"
     gene            32798..33649
                     /gene="tsf"
                     /locus_tag="RHX21_001094"
     CDS             32798..33649
                     /gene="tsf"
                     /locus_tag="RHX21_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HDV1986318.1"
                     /translation="MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKS
                     GAIKAAKKAGNVAADGVIKTKIDGNYGIILEVNCQTDFVAKDAGFQAFADKVLDAAVA
                     GKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIGVLVAAKG
                     ADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDIAMQSGKPKEIAEKMVEG
                     RMKKFTGEVSLTGQPFVMEPSKTVGQLLKEHNAEVTGFIRFEVGEGIEKVETDFAAEV
                     AAMSKQS"
     gene            33796..34521
                     /gene="pyrH"
                     /locus_tag="RHX21_001095"
     CDS             33796..34521
                     /gene="pyrH"
                     /locus_tag="RHX21_001095"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HDV1986319.1"
                     /translation="MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKEL
                     VELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNA
                     RLMSAIPLNGVCDSYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADV
                     VLKATKVDGVFTADPAKDPTATMYEQLTYSEVLEKELKVMDLAAFTLARDHKLPIRVF
                     NMNKPGALRRVVMGEKEGTLITE"
     gene            34812..35369
                     /gene="frr"
                     /locus_tag="RHX21_001096"
     CDS             34812..35369
                     /gene="frr"
                     /locus_tag="RHX21_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HDV1986320.1"
                     /translation="MISDIRKDAEVRMDKCVEAFKTQISKIRTGRASPSLLDGIVVEY
                     YGTPTPLRQLASVTVEDSRTLKINVFDRSMSPAVEKAIMASDLGLNPNSAGSDIRVPL
                     PPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKEISEDDDRRSQDDV
                     QKLTDAAIKKIEAALADKEAELMQF"
     gene            35461..36657
                     /gene="ispC"
                     /locus_tag="RHX21_001097"
     CDS             35461..36657
                     /gene="ispC"
                     /locus_tag="RHX21_001097"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HDV1986321.1"
                     /translation="MKQLTILGSTGSIGCSTLDVVRHNPEHFRVVALVAGKNVTRMVE
                     QCLEFSPRYAVMDDEASAKLLKTMLQQQGSRTEVLSGQQAACDMAALEDVDQVMAAIV
                     GAAGLLPTLAAIRAGKTILLANKESLVTCGRLFMDAVKQSKAQLLPVDSEHNAIFQSL
                     PQPIQHNLGYADLEQNGVVSILLTGSGGPFRETPLRDLATMTPDQACRHPNWSMGRKI
                     SVDSATMMNKGLEYIEARWLFNASASQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDM
                     RTPIAHTMAWPNRVNSGVKPLDFCKLSALTFAAPDYDRYPCLKLAMEAFEQGQAATTA
                     LNAANEITVAAFLAQQIRFTDIAALNLSVLEKMDMREPQCVDDVLSVDANAREVARKE
                     VMRLAS"
     gene            36846..37604
                     /gene="ispU"
                     /locus_tag="RHX21_001098"
                     /gene_synonym="uppS"
     CDS             36846..37604
                     /gene="ispU"
                     /locus_tag="RHX21_001098"
                     /gene_synonym="uppS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308203.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2E,6E)-farnesyl-diphosphate-specific
                     ditrans,polycis-undecaprenyl-diphosphate synthase"
                     /protein_id="HDV1986322.1"
                     /translation="MLSATQPLSEKLPAHGCRHVAIIMDGNGRWAKKQGKIRAFGHKA
                     GAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRH
                     NVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEK
                     VQQGNLQPDQIDEEMLNQHVCMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDV
                     LWPDFDEQDFEGALNAFANRERRFGGTEPGDETA"
     gene            37617..38474
                     /gene="cdsA"
                     /locus_tag="RHX21_001099"
     CDS             37617..38474
                     /gene="cdsA"
                     /locus_tag="RHX21_001099"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414717.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HDV1986323.1"
                     /translation="MLKYRLISAFVLIPVVIAALFLLPPVGFAIVTLVVCMLAAWEWG
                     QLSGFTTRSQRVWLAVLCGLLLALMLFLLPEYHRNIHQPLVEISLWASLGWWIVALLL
                     VLFYPGSAAIWRNSKTLRLIFGVLTIVPFFWGMLALRAWHYDENHYSGAIWLLYVMIL
                     VWGADSGAYMFGKLFGKHKLAPKVSPGKTWQGFIGGLATAAVISWGYGMWANLDVAPV
                     TLLICSIVAALASVLGDLTESMFKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFAC
                     LLLLVFRTL"
     gene            38486..39838
                     /gene="rseP"
                     /locus_tag="RHX21_001100"
     CDS             38486..39838
                     /gene="rseP"
                     /locus_tag="RHX21_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma E protease regulator RseP"
                     /protein_id="HDV1986324.1"
                     /translation="MLSFLWDLASFIVALGVLITVHEFGHFWVARRCGVRVERFSIGF
                     GKALWRRTDKLGTEYVIALIPLGGYVKMLDERAEPVVPELRHHAFNNKSVGQRAAIIA
                     AGPVANFIFAIFAYWLVFIIGVPGVRPVVGEIAANSIAAEAQIAPGTELKAVDGIETP
                     DWDAVRLQLVDKIGDESTTITVAPFGSDQRRDVKLDLRHWAFEPDKEDPVSSLGIRPR
                     GPQIEPVLENVQPNSAASKAGLQAGDRIVKVDGQPLTQWVTFVMLVRDNPGKSLALEI
                     ERQGSPLSLTLIPESKPGNGKAIGFVGIEPKVIPLPDEYKVVRQYGPFNAIVEATDKT
                     WQLMKLTVSMLGKLITGDVKLNNLSGPISIAKGAGMTAELGVVYYLPFLALISVNLGI
                     INLFPLPVLDGGHLLFLAIEKIKGGPVSERVQDFCYRIGSILLVLLMGLALFNDFSRL
                     "
     gene            39868..42300
                     /gene="bamA"
                     /locus_tag="RHX21_001101"
     CDS             39868..42300
                     /gene="bamA"
                     /locus_tag="RHX21_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamA"
                     /protein_id="HDV1986325.1"
                     /translation="MAMKKLLIASLLFSSATVYGAEGFVVKDIHFEGLQRVAVGAALL
                     SMPVRTGDTVNDEDISNTIRALFATGNFEDVRVLRDGDTLLVQVKERPTIASITFSGN
                     KSVKDDMLKQNLEASGVRVGESLDRTTIADIEKGLEDFYYSVGKYSASVKAVVTPLPR
                     NRVDLKLVFQEGVSAEIQQINIVGNHAFTTDELISHFQLRDEVPWWNVVGDRKYQKQK
                     LAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYVTVNITEGDQYKLSGVEVSGN
                     LAGHSAEIEQLTKIEPGELYNGTKVTKMEDDIKKLLGRYGYAYPRVQSMPEINDADKT
                     VKLRVNVDAGNRFYVRKIRFEGNDTSKDAVLRREMRQMEGAWLGSDLVDQGKERLNRL
                     GFFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWL
                     GTGYAVGINGTKNDYQTYAELSVTNPYFTVDGVSLGGRLFYNDFQADDADLSDYTNKS
                     YGTDVTLGFPINEYNSLRAGLGYVHNSLSNMQPQVAMWRYLYSMGEHPSTSDQDNSFK
                     TDDFTFNYGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVTLDTATYVPIDDD
                     HKWVVLGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAVYFPHQASNY
                     DPDYDYECATQDGAKDLCKSDDAVGGNAMAVASLEFITPTPFISDKYANSVRTSFFWD
                     MGTVWDTNWDSSQYSGYPDYSDPSNIRMSAGIALQWMSPLGPLVFSYAQPFKKYDGDK
                     AEQFQFNIGKTW"
     gene            42422..42907
                     /gene="skp"
                     /locus_tag="RHX21_001102"
                     /gene_synonym="hlpA"
                     /gene_synonym="ompH"
     CDS             42422..42907
                     /gene="skp"
                     /locus_tag="RHX21_001102"
                     /gene_synonym="hlpA"
                     /gene_synonym="ompH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone Skp"
                     /protein_id="HDV1986326.1"
                     /translation="MKKWLLAAGLGLALATSAQAADKIAIVNMGSLFQQVAQKTGVSN
                     TLENEFKGRASELQRMETDLQAKMKKLQSMKAGSDRTKLEKDVMAQRQTFAQKAQAFE
                     QDRARRSNEERGKLVTRIQTAVKSVANSQDIDLVVDANAVAYNSSDVKDITADVLKQV
                     K"
     gene            42911..43936
                     /gene="lpxD"
                     /locus_tag="RHX21_001103"
     CDS             42911..43936
                     /gene="lpxD"
                     /locus_tag="RHX21_001103"
                     /EC_number="2.3.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-(3-hydroxymyristoyl)glucosamine
                     N-acyltransferase"
                     /protein_id="HDV1986327.1"
                     /translation="MPSIRLADLAQQLDAELHGDGDIVITGVASMQSAQTGHITFMVN
                     PKYREHLGLCQASAVVMTQDDLPFAKSAALVVKNPYLTYARMAQILDTTPQPAQNIAP
                     SAVIDATAKLGNNVSIGANAVIESGVELGDNVIIGAGCFVGNNSKIGAGSRLWANVTI
                     YHEIQIGQNCLIQSGTVVGADGFGYANDRGNWVKIPQIGRVIIGDRVEIGACTTIDRG
                     ALDDTIIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAGSLKIGRYCMIGGASVINGH
                     MEICDKVTVTGMGMVMRPITEPGVYSSGIPLQPNKVWRKTAALVMNIDDMSKRLKSLE
                     RKVNQQD"
     gene            44041..44496
                     /gene="fabZ"
                     /locus_tag="RHX21_001104"
     CDS             44041..44496
                     /gene="fabZ"
                     /locus_tag="RHX21_001104"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDV1986328.1"
                     /translation="MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNV
                     SVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFK
                     RPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA"
     gene            44500..45288
                     /gene="lpxA"
                     /locus_tag="RHX21_001105"
     CDS             44500..45288
                     /gene="lpxA"
                     /locus_tag="RHX21_001105"
                     /EC_number="2.3.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP--UDP-N-acetylglucosamine
                     O-acyltransferase"
                     /protein_id="HDV1986329.1"
                     /translation="MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVL
                     KSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGT
                     VQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVH
                     QFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNA
                     YKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFARSTRGLIR"
     gene            45288..46436
                     /gene="lpxB"
                     /locus_tag="RHX21_001106"
     CDS             45288..46436
                     /gene="lpxB"
                     /locus_tag="RHX21_001106"
                     /EC_number="2.4.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-A-disaccharide synthase"
                     /protein_id="HDV1986330.1"
                     /translation="MTEQRPLTIALVAGETSGDILGAGLIRALKERVPNARFVGVAGP
                     RMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTKRFGELKPDVFVGIDAPDF
                     NITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVP
                     CRFIGHTMADAMPLDPDKNAARDVLGIPHDAHCLALLPGSRGAEVEMLSADFLKTAQL
                     LRQTYPDLEIVVPLVNAKRREQFERIKAEVAPDLSVHLLDGMGREAMVASDAALLASG
                     TAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTDYVSLPNLLAGRELVKELLQEECEP
                     QKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ"
     gene            46433..47029
                     /gene="rnhB"
                     /locus_tag="RHX21_001107"
     CDS             46433..47029
                     /gene="rnhB"
                     /locus_tag="RHX21_001107"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HDV1986331.1"
                     /translation="MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPARPIAGLN
                     DSKKLSEKRRLALYEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAP
                     EYVLIDGNRCPKLPMPAMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFA
                     QHKGYPTAFHLEKLAEHGATEHHRRSFGPVKRALGLAS"
     gene            47066..50548
                     /gene="dnaE"
                     /locus_tag="RHX21_001108"
     CDS             47066..50548
                     /gene="dnaE"
                     /locus_tag="RHX21_001108"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HDV1986332.1"
                     /translation="MSEPRFVHLRVHSDYSMIDGLAKTAPLVKKAAALGMPALAITDF
                     TNLCGLVKFYGAGHGAGIKPIVGADFNVQCDLLGDELTHLTVLAANNTGYQNLTLLIS
                     KAYQRGYGAAGPIIDRDWLIELNEGLILLSGGRMGDVGRSLLRGNSALVDECVAFYEE
                     HFPDRYFLELIRTGRPDEESYLHAAVELAEARGLPVVATNDVRFIDSSDFDAHEIRVA
                     IHDGFTLDDPKRPRNYSPQQYMRSEEEMCELFADIPEALANTVEIAKRCNVTVRLGEY
                     FLPQFPTGDMSTEDYLVKRAKEGLEERLAFLFPDEEERLKRRPEYDERLETELQVINQ
                     MGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVAYALKITDLDPLEFDLLFERFL
                     NPERVSMPDFDVDFCMEKRDQVIEHVADMYGRDAVSQIITFGTMAAKAVIRDVGRVLG
                     HPYGFVDRISKLIPPDPGMTLAKAFEAEPQLPEIYEADEEVKALIDMARKLEGVTRNA
                     GKHAGGVVIAPTKITDFAPLYCDEEGKHPVTQFDKSDVEYAGLVKFDFLGLRTLTIIN
                     WALEMINKRRAKNGEPPLDIAAIPLDDKKSFDMLQRSETTAVFQLESRGMKDLIKRLQ
                     PDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREEISYPDVQWQHESLKPVLEPTYG
                     IILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRSVFAEGAEKNGINAEL
                     AMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTADMDNTEKVV
                     GLVDECWRMGLKILPPDINSGLYHFHVNDDGEIVYGIGAIKGVGEGPIEAIIEARNKG
                     GYFRELFDLCARTDTKKLNRRVLEKLIMSGAFDRLGPHRAALMNSLGDALKAADQHAK
                     AEAIGQADMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLYLTGHPINQYLKE
                     IERYVGGVRLKDMHPTERGKVITAAGLVVAARVMVTKRGNRIGICTLDDRSGRLEVML
                     FTDALDKYQQLLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEAREKYARGLAISL
                     TDRQIDDQLLNRLRQSLEPHRSGTIPVHLYYQRADARARLRFGATWRVSPSDRLLNDL
                     RGLIGSEQVELEFD"
     gene            50561..51520
                     /gene="accA"
                     /locus_tag="RHX21_001109"
     CDS             50561..51520
                     /gene="accA"
                     /locus_tag="RHX21_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HDV1986333.1"
                     /translation="MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLR
                     EKSVELTRKIFADLGAWQIAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIV
                     GGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMQMAERFKMPIITF
                     IDTPGAYPGVGAEERGQSEAIARNLREMSRLGVPVVCTVIGEGGSGGALAIGVGDKVN
                     MLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAH
                     RNPEAMAASLKAQLLADLADLDVLSTEDLKNRRYQRLMSYGYA"
     gene            51619..53760
                     /gene="ldcC"
                     /locus_tag="RHX21_001110"
     CDS             51619..53760
                     /gene="ldcC"
                     /locus_tag="RHX21_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylase LdcC"
                     /protein_id="HDV1986334.1"
                     /translation="MNIIAIMGPHGVFYKDEPIKELESALVAQGFQIIWPQNSVDLLK
                     FIEHNPRICGVIFDWDEYSLDLCSDINQLNEYLPLYAFINTHSTMDVSVQDMRMALWF
                     FEYALGQAEDIAIRMRQYTDEYLDNITPPFTKALFTYVKERKYTFCTPGHMGGTAYQK
                     SPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFGAEQSYIVTN
                     GTSTSNKIVGMYAAPSGSTLLIDRNCHKSLAHLLMMNDVVPVWLKPTRNALGILGGIP
                     RREFTRDSIEEKVAATTQAQWPVHAVITNSTYDGLLYNTDWIKQTLDVPSIHFDSAWV
                     PYTHFHPIYQGKSGMSGERVAGKVIFETQSTHKMLAALSQASLIHIKGEYDEEAFNEA
                     FMMHTTTSPSYPIVASVETAAAMLRGNPGKRLINRSVERALHFRKEVQRLREESDGWF
                     FDIWQPPQVDEAECWPVAPGEQWHGFNDADADHMFLDPVKVTILTPGMDEQGNMSEEG
                     IPAALVAKFLDERGIVVEKTGPYNLLFLFSIGIDKTKAMGLLRGLTEFKRSYDLNLRI
                     KNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRKHDLPGLMLRAFDTLPEMIMTPHQAW
                     QRQIKGEVETIALEQLVGRVSANMILPYPPGVPLLMPGEMLTKESRTVLDFLLMLCSV
                     GQHYPGFETDIHGAKQDEDGVYRVRVLKMAG"
     gene            53817..54206
                     /locus_tag="RHX21_001111"
     CDS             53817..54206
                     /locus_tag="RHX21_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308216.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDV1986335.1"
                     /translation="MLGLKQVHHIAIIATDYAVSKAFYCDILGFTLQSEVYREARDSW
                     KGDLALNGQYVIELFSFPFPPERPSRPEACGLRHLAFSVDDIDAAVAHLESHNVKCEA
                     IRVDPYTQKRFTFFNDPDGLPLELYEQ"
     gene            54271..55569
                     /gene="tilS"
                     /locus_tag="RHX21_001112"
     CDS             54271..55569
                     /gene="tilS"
                     /locus_tag="RHX21_001112"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HDV1986336.1"
                     /translation="MTLTLNRQLLTSRQILVAFSGGLDSTVLLHQLVQWRTENPGVTL
                     RAIHVHHGLSANADAWVTHCENVCQQWQVPLVVERVQLAQEGLGIEAQARQARYQAFA
                     RTLLPGEVLVTAQHLDDQCETFLLALKRGSGPAGLSAMGEVSEFAGTRLIRPLLARTR
                     GELAQWALAHGLRWIEDESNQDDSYDRNFLRLRVVPLLQQRWPHFAEATARSAALCAE
                     QESLLDELLADDLAHCQTSQGTLQIAPMLAMSDARRAAIIRRWLAGQNAPMPSRDALV
                     RIWQEVALAREDASPCLRLGAFEIRRYQSQLWWIKSVTGQSETIVPWQTWLQPLELPA
                     GLGSVQLTAGGDIRPPRADEAVSVRFKAAGLLHIVGRNGGRKLKKIWQELGVPPWLRD
                     TTPLLFYGETLIAAAGVFVTQEGVAEGENGVSFVWQKTLS"
     gene            complement(55618..55878)
                     /gene="rof"
                     /locus_tag="RHX21_001113"
     CDS             complement(55618..55878)
                     /gene="rof"
                     /locus_tag="RHX21_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho-binding antiterminator"
                     /protein_id="HDV1986337.1"
                     /translation="MSMNDTYQPINCDDYDNLELACQHHLMLTLELKDGEKLQAKASD
                     LVSRKNVEYLVVEAAGETRELRLDKITSFSHPEIGTVVVSES"
     gene            complement(55865..56065)
                     /locus_tag="RHX21_001114"
     CDS             complement(55865..56065)
                     /locus_tag="RHX21_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeP family protein"
                     /protein_id="HDV1986338.1"
                     /translation="MEKYCELIRKRYAEIASGDLGYVPDALGCVLKVLNEMAADDALS
                     EAVREKAAYAAANLLVSDYVNE"
     gene            56231..56776
                     /locus_tag="RHX21_001115"
     CDS             56231..56776
                     /locus_tag="RHX21_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeQ family protein"
                     /protein_id="HDV1986339.1"
                     /translation="MALKATIYKATVNVADLDRNQFLDASLTLARHPSETQERMMLRL
                     LAWLKYADERLQFTRGLCADDEPEAWLRNDHLGIDLWIELGLPDERRIKKACTQAAEV
                     ALFTYNSRAAQIWWQQNQSKCVQFANLSVWYLDDEQLAKVSAFADRTMTLQATIQDGV
                     IWLSDDKNNLEVNLTAWQQPS"
     gene            56773..57195
                     /gene="arfB"
                     /locus_tag="RHX21_001116"
     CDS             56773..57195
                     /gene="arfB"
                     /locus_tag="RHX21_001116"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HDV1986340.1"
                     /translation="MIVISRHVAIPDGELEITAIRAQGAGGQHVNKTSTAIHLRFDIR
                     ASSLPEYYKERLLAASHHLISSDGVIVIKAQEYRSQELNREAALARLVAVIKDLTTEQ
                     KARRPTRPTRASKERRLASKAQKSSVKAMRGKVRSGRE"
     gene            57209..57919
                     /gene="nlpE"
                     /locus_tag="RHX21_001117"
                     /gene_synonym="cutF"
     CDS             57209..57919
                     /gene="nlpE"
                     /locus_tag="RHX21_001117"
                     /gene_synonym="cutF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706138.1"
                     /note="NlpE, an outer membrane lipoprotein, interacts
                     directly with CpxA, the sensor histidine kinase of the Cpx
                     system for response to envelope stress; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response activation lipoprotein
                     NlpE"
                     /protein_id="HDV1986341.1"
                     /translation="MVKKAIVTAMAVISLFTLMGCNNRAEVDTLSPAQAAELKPMPQS
                     WRGVLPCADCEGIETSLFLEKDGTWVMNERYLGAREEPSSFASYGTWARTADKLVLTD
                     SKGEKSYYRAKGDALEMLDREGNPIESQFNYTLEPAQSSLPMTPMTLRGMYFYMADAA
                     TFTDCATGKRFMVANNAELERSYLAARGHSEKPVLLSVEGHFTLEANPDTGAPTKVLA
                     PDTAGKFYPNKDCSSLGQ"
BASE COUNT        13605 a        14368 c        16151 g        13840 t
ORIGIN      
        1 aaaatattta tattcgtaat ataaataaat taccatttgc ttaatttgtc aaatgctctt
       61 gtatgtacga cttcacgcaa cgtctcccca tcaggaaacg ccagctccgg tgcaatctca
      121 aacagcggcc acagcataaa tccacgattc ttcatatcgt agtgcggaac ggtcaggcgt
      181 tcggtattta tcacttcatt accaaacagc atgatatcga gatccagcgt gcgtggtccc
      241 cagcgttcag ctttacgaac acgaccctgt tgcagttcta tgcgctgtgt atggttgagt
      301 aactcttccg gggcgagcga agtttcaagc gccacggcgg cgttgaggta atcgggttga
      361 tcttgcggcc ccagcggtgg ggtgcggtaa aacgaagaaa cggcaagaat gtggctttca
      421 gggatatcgc ctaatgcttt cagggcagca ttgacctgct ccagcggaga ggccagattg
      481 ctgcctatgg caatatacgc cactgtcatg cggtaccctc acgacgcggt gcgcgtttgc
      541 gtggacgacg agtacgacga cgcggtgacg gttcttcatc cagctcgtta agcatccctt
      601 tttgatctgg tggtgcggaa acctggaact caccccacca tttcaccaga cgctgcagtt
      661 cagcattacg ttcaacttca gctcgcaagg ccaacaggtc ataagccgca cggaacttag
      721 gatgctccag cagtttccat gcgcgtttac cctgacgacg ggacatacgc aactgcaact
      781 gccagatatc gcgggttaac gtcgtcagac gtttcgggat tgccagtgaa cggcaggctt
      841 cgtccagcac gtcgttcatc gccagcgcga aagcgtcgtg ataggtcagg ccgctttcct
      901 gggcaatctt ctgtgccgtc tccagcagtg ggtaccagaa catggcggca aacaggaacg
      961 ccgggttcac gcgcatatcg ttatggatac gcgtatcggt attcttcagc acctgttcaa
     1021 tgatccgctc catcgggctg tcgccatttt ccgtgaagta gcgggtaatg gtcgggaaca
     1081 gcggctggaa cagatgatat tcacacaaca gcttataggt atcgtaaccg tagcccgctt
     1141 gtagcagttt aagcgattct tcaaacaggc gtgccggtgg gatatcgttc aacagggtag
     1201 cgaggcgagg gatcggttct gcggtttccg ggctgatgcg catacccaat ttggcggcaa
     1261 aacgtaccgc gcgcagcata cgtaccggat cttcacggta gcgcgtttcc gggttaccaa
     1321 tcagacggat aacgccgtcc ttcagatcct tcataccgcc aacgtaatca cggacggtaa
     1381 aatccgctac gctgtaatag aggctgttga tagtgaaatc gcggcgctgg gcgtcttctt
     1441 cgatggagcc gaaaatgttg tcgcgcagca acatgccgtt ttgcccgcgt tgggaggtcg
     1501 tgcggtcgct gacgttacct tcgtggtgtc cacggaaggt cgcaacttcg ataatctccg
     1561 ggccaaacat cacatgagcc agacggaaac ggcgacccac caggcggcag ttacggaaca
     1621 gtttgcgcac ctgctcaggc gtggcgttag tggttacgtc aaaatctttc ggctttttgc
     1681 cgagtaacag gtcgcgcacg ccgccgccaa ccagccaggc ttcgtatccc gctttattga
     1741 gcctgtacat taccttcagg gcattttcac tgatatcttt gcgggaaata gcatgctgct
     1801 cacgcgggat caccgtcacc tgtggacggg cgactgcctg ttcagcctcg ctttcctcgc
     1861 ggcttagcac cttgcggcaa aaattagcga ctcgggtaaa aatagtacac ctcggtagtg
     1921 tcaaacatca ttcaggacaa aaaaatagcg gctaatcata gctcagcatg acgcatttga
     1981 gaatgttgaa tttacaattg ccgactcggg cacggcggta agccgccagt ttttgacggc
     2041 tgactgaagg atttgctcga cgctgaaatc ctgccagtgt gcttctgcct gctgccccag
     2101 aaattgaagt gccgcgatta gtaccgggcg tggatcgcct ttcggcaacg caggcgcatg
     2161 attctgcttg gaaagtttag cgccttgtgg attaagcgcc agcggcagat gaatgtaatc
     2221 tggcactttc cagccaaaaa gctggtacag cgagatttgc cttactgttg gttcaatcag
     2281 atcagcccca cgcactattt ctgtaacgcc ctggaaatga tcatcaacca caacagccag
     2341 gttgtaggcg aacaacccat cacggcgatg aatgataaaa tcttcccgtg ccagtttttc
     2401 gtcggcgtga ataatgccgc gcagctggtc agtaaattgc gtgaccggat gctgctggcg
     2461 gatacgcact gcggcattgt ctggtccatg atgcaacacc cggcaatgac cgtcgtaaat
     2521 accgccaatg ctttgaatac gcgcacgcgt acaggtgcag taataactta gtccttgttc
     2581 atgtaaccag gcgagtgctt cacgataggc gtggtgacgt tgcgattgcc agagaacatc
     2641 gccgtcccag tgcagaccgt aatgttccag ctggcgcagg atagtttctg cggcaccggg
     2701 aacttcacga ggcgggtcga tatcttctat gcgtaccagc cagcgacctt gccgggcgcg
     2761 agcctgcaaa tagctgccga gcgcggcgat cagagagcca aaatgaagct cgccggaagg
     2821 agagggggcg aagcggccaa tatactgtgt gtctgtcatc tctttgaaca aaaaataagg
     2881 cgggagcatt tcccgcctgt ggtaaacgtg atggaacggc tgtaattagc cagccatctg
     2941 tttttcgcga atttcagcca gcgttttgca gtcgatgcac agatcggctg tcgggcgcgc
     3001 ttccagacgg cgaataccaa tttcaacacc gcaggattcg cagtagccga aatcttcgtc
     3061 ttccactttt ttcagcgtct tctcgatctt tttgatcagc ttacgctcgc gatcgcggtt
     3121 acgcagttcg aggctgaact cttcttcctg ggctgcacgg tctaccgggt ccgggaagtt
     3181 ggctgcttca tcctgcatat gtgtaacggt gcgatcgact tcatccctga gttgattacg
     3241 ccatgcttcc agaatacgac ggaagtgcgc cagctgggct tcattcatat actcttcgcc
     3301 cggcttctcc tgatatggtt ccaccccagc gatggcgaga atactcaggg acgatgtttt
     3361 acggttttgc ccttcttgca tgttgcttct ccttaacacg cactatcgat ccccatgttc
     3421 gggggaaaaa tgaggccgct ataaatagca gatgcttttc cggatagcaa ttatctaaac
     3481 gtaacacttg acaactgtgt gaggaaaagc gtatttgcgc acgcgaccag aatgtaaatt
     3541 aaccagttac ttactttact acaatgtaac cggcagtgat tttttaagag ccatgccttc
     3601 agcagaaatt tccgctttgt aagccagaat ttctaccccc ctctgttgag cttctgacaa
     3661 tagttgcgcg tatttctcat cgatgtggcg cgcgggtgaa aaccgtgtaa tggctgaatg
     3721 cagcacggcg aaaaagataa ccgcacgctg gccttcagcc gctacgctca tcaactcccg
     3781 aaggtgtttc tgacctcgtt cagtgaccgc atcgggaaaa tatccctgtt cgttctccgc
     3841 taacgtaacc gatttcactt caatatagca gtctggacgc gaatccgcct gcaacataaa
     3901 gtcaatacgg ctgcgttctg cgccgtattt tacttcgctt ttcagcgagc tatagcctga
     3961 cagttctgaa attgattcat taaggatagc ctctttcgtc aacctgttag cccaaagcgt
     4021 gttgacgcaa ataaatgcgc cgctctggct ttgagttaat tcccaggtgt gtgggtattt
     4081 ccgtttggtg ttgtctgaag tcgaatacca gacggtatcg ccaggcgttg cacaaccggt
     4141 cattgcaccc gtattcgggc agtgtagcgt taattcgcga ccatcgggtg tgatcacatc
     4201 ggctaaaaaa cgtttgtaac gctgaattag cgtcgcgcgc tgtagagggg gagagaattc
     4261 cattgcgaca atccttgtta ttgcgttagc gcccagcgtt ttagcggcgt gtagcgtgtg
     4321 cgtccacggg caaacgagga ggcgtaaagg gtgaactccg tcaccgcata agaccagtta
     4381 aaacctggcg gcgggattgt caccgcctcg ctggcgtcgc gcaataaggt aatatgtgga
     4441 tgaaacggac gattgctttg aaaacaaccg ctgcgggcag cctgtgaacg gagcatattc
     4501 gccagctgga ttaagccgcg tggaggctga cgcatcccta accacaccac acgcgaacgc
     4561 agccattgtc cggcgtcatc aagcgtgagt gtgaaaccag gttgacgaat ccgtccggct
     4621 aaaagagaaa gcgccttctc tttctcggcg ctcacttcgc ctaaaaatgc cagagtcaga
     4681 tgcaaattat cggcggcgac cggacgtccc gcctcaggtg ggaagtgtgt ggcgcgccaa
     4741 tggataatct gttcgcggat ttctgcaggt aagtcgatag caaagaacag acgttgcggt
     4801 tcagacatgt gaggcactcg gttatgaatt accgcgatgc tacaatgtgg cgcgaagaat
     4861 gttaaccctc tggagcgttt tgtgtcgtcg ttgcccgttg ctgccgtctt atctgaatta
     4921 cttaccgctc tcgattgtgc gccgcaggta ttattaagtg cgccgaccgg ggccgggaaa
     4981 tcaacctggc tgccgctgca actgctggcg catcccggca ttaacgggaa aattatcctg
     5041 ctggagccgc gtcgtctggc ggcgcgtaac gtcgcgcaac gactggcgga gctgcttaac
     5101 gaaaagccag gcgataccgt tggctaccgg atgcgtgcgc aaaactgcgt cgggccgaat
     5161 acccgcctgg aagtggttac cgaaggcgtg ctgacgcgca tgatccagcg tgacccggaa
     5221 ctgagcggtg ttggattggt gatcctcgat gaatttcatg agcgcagctt gcaggcggat
     5281 ttggcgttgg cgctgttact cgatgtgcaa caaggtctgc gtgatgacct taaactgctg
     5341 attatgtcgg ctacgctgga taacgaccgc ttgcagcaaa tgctgccaga agcgcccgtc
     5401 gtcatctcag aagggcgctc gtttccggtt gaacgccatt atttaccgct gcccgcgcat
     5461 cagcgttttg acgaagccgt tgcggtagcc accgccgaaa tgctgcgtca ggaaagcgga
     5521 tcattactgt tatttttacc tggcgtcgga gaaattcagc gtgtgcagga acaactggct
     5581 tcgcgcatcg gcagtgatgt gttgctctgc ccgctgtatg gcgcgttgtc gctgaacgat
     5641 cagcgaaaag cgatcctccc ggcaccgcaa gggatgcgca aagtggtgct ggcgaccaat
     5701 attgctgaaa ccagtttaac cattgaaggt attcgtctgg tggtggattg tgcccaggag
     5761 cgtgtggcgc gttttgatcc gcgcacgggg cttacgcgac tgattactca acgcgttagc
     5821 caggcatcca tgacgcagcg tgccgggcgc gccgggcgtc tggagccggg tatcagcctg
     5881 catttaatcg ccaaagaaca agcagaacgc gccgcggcgc aaagtgaacc ggagatctta
     5941 caaagcgatc tttccggttt gctgatggaa ttactgcaat ggggatgcag cgatccggcg
     6001 cagatgagct ggctggatca accgccaacg gtgaatctac tggccgcgaa acgcctgtta
     6061 caaatgctgg gggcgctgga gggtgaacgg cttagtgcgc aggggcaaaa aatggcagcg
     6121 ctgggtaacg atccgcgttt agcggcaatg ctggttagcg cgaagaacga cgacgaagct
     6181 gctaccgcgg caaaaattgc cgccattctc gaagagccgc cacggatggg caatagtgac
     6241 ctgggcgtgg cgttttcgcg caatcaacca gcctggcagc aacgtagtca gcaactgtta
     6301 aaacgcttaa acgtacgtgg cggtgaggca gacagttcgc ttatcgcgcc gctacttgcc
     6361 ggggcgtttg ccgatcgcat tgctcgtcgc cgtgggcaag atggacgcta tcaactggca
     6421 aacggcatgg gagcgatgct cgatgccaac gacgcgctaa gccgccacga atggttgatc
     6481 gcaccgttat tattgcaggg cagcgcctcg ccggatgcgc ggattttact ggcgttaccg
     6541 gtcgatattg atgaattagt acaacgctgt ccgcagctgg tgcagcaatc tgacaccgtg
     6601 gaatgggatg acgcgcaagg tacgctgaaa gcctggcgtc ggctgcaaat cggtcagttg
     6661 acggtgaaag tgcagccact ggcgaaaccg tcagaagacg agttgcatca ggcgatgctt
     6721 aacggcattc gtgaaaaagg tttaagcgtg ctcaactgga cggcggaagc ggaacagcta
     6781 cgcttgcgtt tgttatgcgc cgcaaagtgg ttgccggaat atgactggcc agcggttgat
     6841 gatgaaagtt tattggcgac gctggaaacg tggctgctgc cacatatgac tggcgtacat
     6901 tcactacgcg gcctgaaatc actcgacatt tatcaggcac tacgcggatt acttgattgg
     6961 ggaatgcagc aacgtctgga tagtgaattg cctgcgcatt acactgtgcc gacgggaagc
     7021 cggatcgcca ttcgttatca tgaagataac ccgcccgcgc tggcggtgag aatgcaagag
     7081 atgtttggcg aggccaccaa tccgacgatc gcccaggggc gcgtgccgct ggtgctggag
     7141 ttgctttcac ctgcccaaag gccattacaa atcacacgag atttgagcgc cttctggaaa
     7201 ggagcgtacc gtgaggtgca aaaagagatg aaagggcgtt atcccaaaca tgtctggccg
     7261 gacgacccgg caaatactgc accgacgcga cggacgaaaa agtattcgta aggttggttt
     7321 tctccctctc cctgtgggag agggccgggg tgagggcatc agcgtgcgca ttccccctca
     7381 ccctaaccct ctccctcaag ggagagggga ccgatcgagc acaaattttg agagatatct
     7441 tcttctgtct tgtaacagaa gaacagaaaa tcgggctttt gcgcctgaat attgcggaga
     7501 aaaagcatgg ccgggaatga ccgcgagcca attggacgca aagggaaacc gacgcgtccg
     7561 gtcaaacaaa aggtaagccg tcgtcgttac gaagatgacg atgattacga cgattatgat
     7621 gactatgagg atgaagaacc gatgccgcgc aaaggtaagg gcaaaggcaa agggcgtaag
     7681 cctcgtggca aacgcggctg gctatggcta ctgctaaaac tggctatcgt ttttgccgtg
     7741 ctgatcgcca tttacggcgt ttatctcgat caaaaaattc gtagccgtat tgatggcaag
     7801 gtctggcaac tgcctgcggc agtttatggc cgaatggtca atcttgagcc agacatgacc
     7861 atcagcaaga acgagatggt gaagctgctg gaggcgaccc agtatcgtca ggtgtcgaaa
     7921 atgacccgtc ctggcgaatt taccgtgcag gccaacagca ttgagatgat tcgccgtccg
     7981 tttgatttcc cggacagtaa agaaggacag gtgcgcgcgc gtctgacctt tgatggcgat
     8041 catctggcga cgatcgtcaa tatggagaac aaccgtcagt tcggtttctt ccgtcttgat
     8101 ccgcgtctga tcaccatgat ctcttcgcca aacggtgagc agcgtctgtt tgtgccgcgc
     8161 agtggtttcc cggatttgct ggtggatact ttgctggcga cagaagaccg tcatttttac
     8221 gagcatgatg gaatcagtct ctactcaatc ggacgtgcgg tgctggcaaa cctgaccgcc
     8281 ggacgcacgg tacagggtgc gagtacgctg acgcaacagc tggtgaaaaa cctgttcctc
     8341 tccagcgagc gttcttactg gcgtaaagcg aacgaagctt acatggcgct gatcatggac
     8401 gcgcgttaca gcaaagaccg tattcttgag ctgtatatga acgaggtgta tctcggtcag
     8461 agcggcgaca acgaaatccg cggcttcccg ctggcaagct tgtattactt tggtcgcccg
     8521 gtagaagagc taagcctcga ccagcaggcg ctgttagtcg gtatggtgaa aggggcgtcc
     8581 atctacaacc cgtggcgtaa cccaaaactg gcgctggagc gacgtaatct ggtgctgcgt
     8641 ctgctgcaac agcaacagat tattgatcaa gaactctatg acatgttgag tgcacgtccg
     8701 ctgggtgttc agccacgcgg tggggtgatc tctccacagc cagcctttat gcaactggtg
     8761 cgtcaggagc tgcaggcgaa attaggcgat aaggtaaaag atctctccgg cgtgaagatc
     8821 ttcactacct ttgactcggt ggcccaggac gcggcagaaa aagccgccgt ggaaggcatt
     8881 ccggcactga agaaacagcg taagttgagc gatcttgaaa ctgcgattgt ggtcgtcgac
     8941 cgctttagtg gtgaagttcg tgcgatggtc ggtggttctg agccgcagtt tgcgggctac
     9001 aaccgtgcga tgcaggcgcg tcgttcgatt ggttcccttg caaaaccagc gacttatctg
     9061 actgccttaa gccagccgaa aatctatcgt ctgaatacgt ggattgcgga tgcgccaatc
     9121 gcgctgcgtc agccgaatgg ccaggtctgg tcaccgcaga atgatgaccg tcgttatagc
     9181 gaaagcggca gagtgatgct ggtggatgcg ttgacccgtt cgatgaacgt gccgacggta
     9241 aatctgggga tggcgctggg gctgcctgcg gttacggaga cctggatcaa actgggcgta
     9301 ccgaaagatc agttgcatcc ggttccggcg atgctgctgg gggcgttgaa cttaacgcca
     9361 atcgaagtgg cgcaggcgtt ccagaccatc gccagcggcg gtaaccgtgc accgctttct
     9421 gcactgcgtt cggtaattgc ggaagatggc aaggtgctgt atcagagctt cccacaggcg
     9481 gaacgcgctg ttccggcgca ggcggcgtat ctgacactat ggaccatgca gcaggtggta
     9541 caacgcggta cgggtcgtca gcttggggcg aaatacccga acctgcatct ggcagggaaa
     9601 acagggacta ccaacaataa cgtagatacc tggtttgcag gcattgacgg cagcacggtg
     9661 accatcacct gggtaggccg tgataacaac cagccgacca aactgtatgg agccagcggg
     9721 gcaatgtcga tttatcagcg ttatctggct aaccagacgc caacgccgct gaatcttgtt
     9781 ccgccagaag atattgcaga tatgggcgtg gactacgacg gcaactttgt ttgcagcggt
     9841 ggcatgcgtg tcttgccggt ctggaccagc gatccgcaat cgctgtgcca gcagagcgag
     9901 atgcagcagc agccgtcagg caatccgttt gatcagtctt ctcagccgca gcaacagccg
     9961 caacagcaac ctgctcagca agagcagaaa gacagcgacg gtgtagccgg ttggatcaag
    10021 gatatgtttg gtagtaatta acatctaagc gtgaaatacc ggatggcgag ttgccatccg
    10081 gtaaaataac atcccatcta agatattaac cctttctttt catctggttg tttattaacc
    10141 cttcaggaac gctcagattg cgtaccgctt gcgaacccgc cagcgtttcg aatattatct
    10201 tatctttata ataatcattc tcgtttacgt tatcattcac tttacatcag agatatacca
    10261 atggcgcgtt ccaaaactgc tcagccaaaa cactcactgc gtaaaatcgc agttgtagta
    10321 gccacagcgg taagcggcat gtctgtttat gcacaggcag cggttgaacc gaaagaagac
    10381 actatcaccg ttaccgctgc acctgcgccg caagaaagcg catgggggcc tgctgcaact
    10441 attgcggcgc gacagtctgc taccggcact aaaaccgata cgccgattca aaaagtgcca
    10501 cagtctattt ctgttgtgac cgccgaagag atggcgctgc atcagccgaa gtcggtaaaa
    10561 gaagcgctta gctacacgcc gggtgtctct gttggtacgc gtggcgcatc caacacctat
    10621 gaccacctga tcattcgcgg ctttgcggca gaaggccaaa gccagaataa ctatctgaat
    10681 ggcctgaagt tgcagggcaa cttctataac gatgcggtca ttgacccgta tatgctggaa
    10741 cgcgctgaaa ttatgcgtgg cccggtttcc gtgctttacg gtaaaagcag tcctggcggc
    10801 ctgttgaata tggtcagcaa gcgtccgacc accgaaccgc tgaaagaagt tcagtttaaa
    10861 gccggtactg acagcctgtt ccagactggt tttgacttta gcgattcgtt ggatgatgac
    10921 ggtgtttact cttatcgcct gaccggtctt gcgcgttctg ccaatgccca gcagaaaggg
    10981 tcagaagagc agcgttatgc tattgcaccg gcgttcacct ggcgtccgga tgataaaacc
    11041 aatttcacct tcctttctta cttccagaac gagccggaaa ccggttatta cggctggttg
    11101 ccgaaagagg gaaccgttga gccgctgccg aacggtaagc gtctgccgac agactttaat
    11161 gaaggggcga agaacaacac ctattctcgt aatgagaaga tggtcggcta cagcttcgat
    11221 cacgaattta acgacacctt tactgtgcgt cagaacctgc gctttgctga aaacaaaacc
    11281 tcgcaaaaca gcgtttatgg ttacggcgtc tgctccgatc cggcgaatgc ttacagcaaa
    11341 cagtgtgcgg cattagcgcc agcggataaa ggccattatc tggcacgtaa atacgtcgtt
    11401 gatgatgaga agctgcaaaa cttctccgtt gatacccagt tgcagagcaa gtttgccact
    11461 ggcgatatcg accacaccct gctgaccggt gtcgacttta tgcgtatgcg taatgacatc
    11521 aacgcctggt ttggttacga cgactctgtg ccactgctca atctgtacaa tccggtgaat
    11581 accgatttcg acttcaatgc caaagatccg gcaaactccg gcccttaccg cattctgaat
    11641 aagcagaaac aaacgggcgt ttatgttcag gatcaggcgc agtgggataa agtgctggtc
    11701 accctgggcg gtcgttatga ctgggcagat caagaatctc ttaaccgcgt tgctgggacg
    11761 accgataaac gtgatgacaa acagtttacc tggcgtggtg gtgttaacta cctgtttgat
    11821 aatggtgtaa caccttactt cagctatagc gaatcgtttg aaccttcttc gcaagttggg
    11881 aaggatggta atattttcgc accgtctaaa ggtaagcagt atgaagtcgg cgtgaaatat
    11941 gtaccggaag atcgtccgat tgtagttact ggtgccgtgt ataatctcac taaaaccaac
    12001 aacctgatgg cggaccctga gggttccttc ttctcggttg aaggtggcga gatccgcgca
    12061 cgtggcgtag aaatcgaagc gaaagcggcg ctgtcggcga gtgttaacgt agtcggttct
    12121 tatacttaca ccgatgcgga atacaccacc gatactacct ataaaggcaa tacgcctgca
    12181 caggtgccaa aacacatggc ttcgctgtgg gctgactata ccttctttga cggtccgctt
    12241 tcaggtctga cgctgggcac cggtggtcgt tatactggct ccagctatgg tgatccggct
    12301 aactccttta aagtgggaag ttatacggtc gtggatgcgt tagtgcgtta tgatctggcg
    12361 cgagtcggca tggcgggctc caacgtggcg ctgcatgtta acaacctgtt cgatcgtgaa
    12421 tacgtcgcca gctgctttaa cacttatggc tgcttctggg gcgcagaacg tcaggtcgtt
    12481 gcaaccgcaa ccttccgttt ctaatttctc ttttggggca cggatttccg tgcccatttc
    12541 acaagttggc tgttatgcag gaatacacga atcattccga taccactttt gcactgcgta
    12601 atatctcctt tcgtgtgccc gggcgcacgc ttttgcatcc gctgtcgtta acctttcctg
    12661 ccgggaaagt gaccggtctg attggtcaca acggttctgg taaatccact ctgctcaaaa
    12721 tgcttggccg tcatcagcct ccgtcagaag gggagattct tcttgatgcc cagccgctgg
    12781 aaagctggag cagcaaagcg tttgcccgca aagtggctta tttgccgcag cagcttcctc
    12841 cggcagaagg gatgaccgtg cgtgaactgg tggcgattgg tcgttacccg tggcatggcg
    12901 cgttggggcg ctttggggcg gcagatcgcg aaaaagtcga ggaagctatc tcgctggttg
    12961 gcttaaaacc gctggcgcat cggctggtcg atagtctctc tggcggcgaa cgtcaacggg
    13021 cgtggatcgc catgctggtg gcgcaggata gctgttgtct gttgctcgac gaaccgactt
    13081 cggcgctgga tatcgcccac caggttgatg tgctggcgct ggtgcaccgt ttaagtcagg
    13141 agcgtggcct gacggtcatt gccgtgttgc acgatatcaa tatggcggca cgctactgtg
    13201 attatctggt cgccctgcgc ggtggtgaaa tgattgctca gggaacgcct gcggaaatta
    13261 tgcgcggcga aactctcgaa atgatttatg gcatcccgat gggtattttg ccgcatccgg
    13321 cgggtgctgc acctgtgagt tttgtttatt gatgagcggc ttacctctta tttcgcgccg
    13381 tcgactgtta acggcgatgg cgctttctcc gttgttatgg cagatgaata ccgcccacgc
    13441 ggcggctatt gaccccaatc gtattgtggc gctggagtgg ttgccggtgg aattactgct
    13501 ggcgctcggc atcgtgcctt acggcgtggc ggataccatc aactatcgcc tgtgggtcag
    13561 cgaaccacca ttgccggact cagtgattga cgtcggtttg cgtacagaac ctaaccttga
    13621 actgctgacc gaaatgaaac cgtcgtttat ggtctggtcg gcaggatatg gcccttcatc
    13681 agaaatgctg gcacgtattg cgccgggtcg cggatttaac ttcagcgatg gcaaacagcc
    13741 gttggcgatg gcgcgtaaat cgctgacgga aatggcagat ttacttaacc tgcaaagcgc
    13801 agcggaaacg catttagcgc aatacgaaga ctttatccgc agcatgaaac cccgctttgt
    13861 gaagcgtggt gcacgcccgt tactgctgac gacgcttatc gatccgcgcc atatgctggt
    13921 cttcggtcca aacagcttgt tccaggaaat tctcgatgag tacggcatcc caaatgcctg
    13981 gcaaggggaa accaacttct ggggcagtac cgccgtcagt atcgatcgtc tggcggcgta
    14041 taaagacgtt gatgtgctct gttttgatca cgacaacagc aaagacatgg atgcgctaat
    14101 ggcaaccccg ctgtggcagg ccatgccgtt tgtccgcgcc ggacgctttc agcgcgtacc
    14161 cgcagtctgg ttttatggtg cgacgctctc ggcaatgcac tttgtgcgcg ttctggataa
    14221 cgccatcgga ggtaaagcgt gagtaaacga attgcgcttt ttccggcgtt attgctggcg
    14281 ctgctggtga ttgtcgctac ggcgctgacc tggatgaact tttcgcaggc gctgccgcgc
    14341 agtcagtggg cgcaggccgc ctggtcgccg gatattaacg tcatcgagca gatgattttt
    14401 cactacagct tgttaccacg tctggcgatt tctctactgg tgggcgcggg cctggggctg
    14461 gtgggcgtgc tgtttcagca agtgctgcgt aacccgctgg cggaaccgac gacgttgggc
    14521 gttgctacag gcgcgcaact ggggattacc gtcaccacgc tctgggcgat ccccggtgct
    14581 atggcgagcc agtttgccgc gctggtgggc gcttgtgtcg ttggcttaat cgtctttggc
    14641 gtcgcgtggg ggaaacggct ttcgccggtt acgcttattc tcgcggggct ggtggtgagc
    14701 ctttattgcg gggcaattaa tcagctactg gttatcttcc atcacgacca gctgcaaagc
    14761 atgttcctgt ggagcaccgg aacgctgacg caaaccgact ggggcggcgt tgagcgttta
    14821 tggccgcagc tgctgggcgg cgtgatgctg acgttactgc tacttcgtcc gttaaccctg
    14881 atggggcttg atgatggcgt ggcgcgcaat ctcgggctgg ccttatcgct cgcgcgtctg
    14941 gctgcgctgt cgctggcgat agtcatcagt gcgctgctgg tgaatgcggt ggggattatc
    15001 ggctttatcg ggttgttcgc gccactgctg gcaaaaatgc tgggggcgcg gcgtttgttg
    15061 ccacggttga tgctggcgtc gctgattggt gcgttaattc tgtggctttc tgatcaaatc
    15121 atcctctggc tgactcgcgt gtggatggaa gtgtccaccg gttcggtcac tgcgttgatc
    15181 ggtgcgccgc tgctactgtg gctgctgccg cgtttacgga gcattagcgc gccggatatg
    15241 aaggtcaacg attgtgtcgc gactgaacgc caacatgtgc tggcgtttgt cctcgcgggc
    15301 ggcgtgctgc tgttgatggc tgtggtagtg gcgctgtcgt ttggtcgtga tgcgcacggc
    15361 tggacgtggg cgagcggggc gttgcttgag gatttgatgc cctggcgctg gccgcgaatt
    15421 atggcggcgc tgtttgcggg cgtcatgctg gcggtggcgg gctgtattat tcagcggctg
    15481 accggaaacc cgatggcaag cccggaagtg ctggggatta gctctggcgc agcgtttggc
    15541 gtggtgttga tgctgtttct ggtgccgggt aatgcctttg gctggctgtt acctgcaggc
    15601 agtctcgggg cggcggtgac gctgttgatc attatgatcg ccgccggacg cggtggattt
    15661 tccccacacc gcatgttact ggcggggatg gcgttaagta ccgcgttcac catgcttttg
    15721 atgatgttgc aggcaagtgg tgacccgcga atggcgcaag tgctgacctg gatttccggt
    15781 tcgacctaca acgcgaccga tgcgcaggtc tggcgcaccg gaattgtgat ggtgattttg
    15841 ctggcgatta ccccgctgtg ccgccgctgg ctgaccattt taccgctggg tggtgatacc
    15901 gcccgagccg taggaatggc gctaacgccg acgcgaattg cgctgctgct gttagcggct
    15961 tgcctgacgg cgaccgcgac gatgactatt ggaccgttga gttttgttgg tttaatggca
    16021 ccgcatattg cgcggatgat gggctttcga cggacgatgc cgcacatcgt aatttcggcg
    16081 ctggtgggtg gtttactgct ggtgttcgct gactggtgtg ggcggatggt gctgtttcca
    16141 ttccagatcc cggcggggct gctgtcaacc tttatcggcg cgccatattt tatctatttg
    16201 ttgagaaagc agagccgtta attgaatgcc tcgcccggtg ggcgaggcaa aatcatcaca
    16261 acttcgcaaa cacccgtcgt gcagcatcga tggtgttatt gatatcttcc atgctgtgcg
    16321 ccacggacat aaagcccgct tcaaacgctg acggtgccag gtaaacacct tcgtccagca
    16381 tcatatggaa gaaacgctta aagcgttcca cgtcacaggc catcacatcc tgatagcacg
    16441 tcacggactc ggcgtcggta aagaaaatac cgaacatgcc gccaacgtgg ttaacgacca
    16501 gcggaattcc ggcttcttct gccgcttcca gcagaccttc tgccagacgt gttgtcagct
    16561 catccagcgt ttcgtgaacg cccggctgcg cgacttcatt cagacaggcg aaacccgctg
    16621 ccatcgcaat tgggttaccg gaaagcgtac ccgcctgata gaccggaccc gtcggggcca
    16681 gcgcatccat tacatcacga cgaccaccga atgcgcctac cggcattcca ccgccgatga
    16741 tttttccgag gcaggttaaa tctggcacta cgccgtaata atcctgtgca ccagccagtg
    16801 ccacgcggaa gccagtcatt acttcatcga tgatcagcaa tgcgccaaat tcgtcgcaca
    16861 gcgcgcgcag acctggcagg aactctggca gcggcggaac acagttcata ttgcctgcca
    16921 ccggctcaac gataatacag gcaatctctt gcgggtattg ctcaaacgcg gcgcgtacag
    16981 aagccagatc gttataagta caggttaagg tatgtttggc gaaatctgcc ggaacacccg
    17041 gcgagtttgg ctggcctaac gtgagtgcgc cagaaccggc tttcaccagc aggcagtcag
    17101 cgtgaccgtg gtaacaacct tcaaatttaa tgattttgtc gcgaccggta aaaccacggg
    17161 ccaggcggat ggcgctcatg gtcgcttcag tgccggagtt caccatgcgc accatatcca
    17221 tggtcgggac cagttcggtc accagttgcg ccattttcac ttccatttcg gttggtgcac
    17281 caaagcttaa accacgctcg gcggcttcaa tcacggcatt gcggattgcc ggatggttat
    17341 ggcccagcac catcggcccc caggaaccga cataatcgat ataggctttg ccatcaacat
    17401 cgtacagata agcgccgtcc gctttttcga taaacagtgg agtgccgccc acgccagtaa
    17461 aggcgcgaac aggggagttc acaccgccag ggatcagctc gcgcgctgcg ctgtaaagat
    17521 tttcagactt actcatggag ggttcctgat tcgtagaaaa agtgaatggc tgctattcta
    17581 tgttattcat aacaagttaa atactcgtca aacatcaggc tgcttgtact ggtgcaatcc
    17641 tgatttctta gagtataaaa gttttgtgca tttgaaacat tacgctttgc aaaggatttt
    17701 catggaacgt gcgagtaaaa tgccgtcatc ttatttgtat gaccaataag tgatcattgg
    17761 atgaaaactg atactccctc tttagaaaca ccgcaggccg cgcgcctgcg acgcagacaa
    17821 ctgattcgcc aacttcttga gcgcgataaa accccgttag ccattttgtt tatggcggca
    17881 gtcgtcggca cgcttgtcgg gctggcagcg gttgcttttg acaaaggtgt cgcctggttg
    17941 cagaaccaac gtatgggggc gctggtacat actgctgata attatccgct actgttaacc
    18001 gtcgcttttc tctgttcggc ggtgctggcg atgttcggct actttttggt gcgcaaatac
    18061 gcgcccgaag cagggggatc ggggatcccg gaaattgaag gggcgctgga agatcaacgt
    18121 cctgttcgct ggtggcgtgt attgccggtg aaattctttg gcgggctggg gacactcggc
    18181 ggaggcatgg tgctagggcg cgaaggacca accgtgcaga tcggcggcaa tatcggtcgc
    18241 atggtgcttg atattttccg cctgaaaggt gatgaagctc gccatacgct gctggcaacc
    18301 ggtgctgctg cggggctggc tgcggccttt aacgcgccgc tggcgggtat tttgtttatt
    18361 atcgaagaga tgcgtccgca gtttcgctat acgttaattt cgattaaagc ggtatttatt
    18421 ggcgtcatta tgtcgaccat tatgtaccgg atttttaatc atgaagttgc gttgattgac
    18481 gtcggtaaac tttctgatgc gccgcttaat acgctgtggc tttatctgat cctcggtatt
    18541 atttttggca ttttcggccc tatttttaat aaatgggtgc tggggatgca ggatttgctg
    18601 caccgtgtgc acggcggcaa tattaccaaa tgggtactga tgggtggtgc gattggcggt
    18661 ctgtgtggat tgctggggtt tgtggcacca gcaacgtcgg gcggcggttt taacctgatt
    18721 cctatcgcta ccgcggggaa tttcagcatg ggaatgctgg tgtttatctt cgtcgctcgg
    18781 gtcattacca ccttactctg cttctcttcc ggcgcgccgg gcggtatttt tgccccgatg
    18841 ctggcgctgg gtactgtgct gggaaccgct ttcggaatgg ttgccgttga gctgtttccg
    18901 caatatcacc tggaggcggg gacgtttgct attgccggaa tgggggcatt actggcggca
    18961 tctattcgcg cgccgttaac ggggatcatt ctggttctgg agatgaccga taactaccag
    19021 ctcattttgc caatgattat taccggtctt ggcgcaacac tattagcgca atttaccggc
    19081 gggaaaccgc tatactcggc gattcttgcg cgcacgctgg caaaacagga agctgagcaa
    19141 ctggcgcgaa gcaaggctgc atcagccagc gagaatactt gaacgaaata ccagggtatt
    19201 agataatggc gattattatt gggttagaat ttgcccaatt gccgatgtcg tttggagcaa
    19261 aatatgagtg atgacgtagc actgccgctg gagtttaccg acgcagcagc caacaaagtt
    19321 aaaagcctga tcgctgacga agataacccg aatctgaaat tacgcgtgta tatcaccggt
    19381 ggcggttgca gcggcttcca gtatggtttc acctttgatg atcaggtgaa cgaaggcgat
    19441 atgaccatcg aaaaacaggg cgttggcctg gtggttgatc cgatgagcct gcaatatctg
    19501 gtcggcggtt ccgttgacta caccgaagga ctggaaggtt ctcgtttcat cgtgaccaac
    19561 ccgaacgcga aaagcacctg cggttgcggt tcttccttta gcatctaatc tgttgttcat
    19621 gtgccggata aactatccgg cacatcttct ctcttcaacg cccattctca tccagcgcaa
    19681 acgtcggtag cttaagatgc caacgaatag ccgccagccg aatcaatagc gtcacgacca
    19741 tgcccatcat actggctgtt tccagtggta cggaaaatgt gtaataagcc gtagcgtgga
    19801 caataccgcc gataatacag gcagttgcgt agatttctgt acgtaaaatc atggggatct
    19861 cgcgggccag tacatcacga atgatcccgc cgccaacgcc agtaatgacg cccatacaaa
    19921 ccgcgattaa cggaccggct tccgcattaa aggctttatt cacgccaatg ccgacaaaca
    19981 ccgccagacc aacggcgtcc agcaccggca acatccattt tggtaagcgt cttggctggc
    20041 gcaccagcac gatggtcagc atgctggtga ccattgcaac gaccagatcg gtgggatctt
    20101 tcacccaaaa taccgggccg tgatccagcg ccatgtcgcg aattgttccg ccgcctactg
    20161 cggtaaccac gcccagtacc agaacaccaa aagggtccat acgcaatttt ccggctaaca
    20221 aaacgccgga gatggcaaat accgctgtgc cgactatatc cagccaatag acgagcattg
    20281 ttcaatcccc actgagcacc tgaaaaggtc aggcactaat ctacctgtga aagcgcatta
    20341 cagagctgtt gtgcagcgag gataatacgt gggcttgcac gttcaaacca gtcactcgtg
    20401 agaggaataa cgggaatttt gagctgttca ccccagtatt gtttgatttt aggaatttgg
    20461 tccggtccgc ctgtaatgac aatcgcctgt ggcgagcgtg ctaacacctg ttcgcggcta
    20521 acttgcggcc agggaacccg gctgtcttta aagatgtttt ctccgccaca aacttcgagt
    20581 acctggttct gaatcgactc ttttccactg gtaaatggcg gattaatgcc gaattgcaga
    20641 aaaacacgtt ttttaggttt atcagcatat tgcgctttca attgcgcgta ctgatccagc
    20701 agggattgcg cggcttgttc ggccttgtct ggttgcggac tccagggggc cagttgacgt
    20761 aacgcattgg caatttgttc aatgcttgtc gcatcgaccc acatcacttt tattcccagc
    20821 gaagccagct ggtcaacctg ccgctcggca ttacctccac gccaggcaat caccagatcg
    20881 ggtttcagcg cgacaatgcg ttccagattc atcccctgcc aggtggaaac ctgctcaatc
    20941 ttttgcgctt gtggaggata gtcggaatag ctgctgaccc caaccggcgt gatcccggcg
    21001 gcaaaggcaa gttcagtgtt ggcgggagaa agcgtgatga cgcgcggcgc ggcgttgagc
    21061 cacagtggcg caagaaaaga cagggcgacc agcgccctga acagtgactt agccatgtgc
    21121 aagtttctgc accagtgact caaccatcag gctggactgt ttagcggcaa cagccaggaa
    21181 ctcatcgaag ctaagatgag actgttgatc ggccacgtcg gagatggcgc gtacgacaac
    21241 aaacgggacg ttgaaattgt ggcagacatg ggcgattgcc gtcgcttcca tctctacagc
    21301 aatggcctgt gggaagttgt ggcggatttt cgccagacca acagaaccgt tgatgaaagc
    21361 gtcgccgcta acaatcaggc cacgtacagc gttaagattc agttcggcaa tgcaggcctc
    21421 agcggcagcg atcagtttat cgtcagcttt aaagcctgcc ggacagcctg gtaactgacc
    21481 gtattcataa ccaaatgccg tgacatccgc gtcgtgataa cgtgcttcgt ccgagacaac
    21541 gatatcgccc actttcagcg ttggtgccag gccaccggca gaaccggtgt taataatcac
    21601 atctggcttg cagtgttcca acagcagagt ggcacccagc gccgcagcga ctttaccgat
    21661 gcccgatttc agaagcgcaa cctcggttcc attcagttgg ccggtataga tttcgcaacc
    21721 gccgagactg atagtttgac ggttttcgat tttgtcacgc agcagcgtaa cttcttcttc
    21781 cattgcacca atgatgccga ttttcataga tttactcgcg ataagcccga tttgaaggca
    21841 tagtttacca tgcgcttacg gggaagcgta tttctcacgc gggagaggac atggcacaga
    21901 ttgatttccg aaaaaaaata aactggcatc gtcgttaccg ttcaccgcag ggcgttaaaa
    21961 ccgaacatga gatcctgcgg atcttcgaga gcgatcgcgg gcgtatcatc aactctccgg
    22021 caattcgtcg tctgcaacaa aagacgcagg tttttccatt ggagcgcaat gccgccgtgc
    22081 gcacgcgtct tacccactcg atggaagtcc agcaggtggg gcgctacatc gccaaagaaa
    22141 ttttaagccg tctgaaagag cttaaattgc tggaagcata cggcctggat gaactgaccg
    22201 gaccttttga aagcattgtt gagatgtcat gcctgatgca cgatatcggc aatccgccgt
    22261 ttggtcattt tggcgaagca gcgataaatg actggtttcg ccaacgtttg catccggaag
    22321 atgccgaaag ccagcctctg actgacgatc gctgcagcgt ggcggcacta cgtttacggg
    22381 acggggaaga accgcttaac gagctgcggc gcaagattcg tcaggactta tgtcattttg
    22441 aggggaatgc acaaggcatt cgtctggtgc atacattgat gcggatgaat ctcacctggg
    22501 cacaggttgg cggtatttta aaatataccc gtccggcgtg gtggcgtggc gaaacgcctg
    22561 agacacatca ctatttaatg aaaaagccgg gttattatct ttctgaagaa gcctatattg
    22621 cccggttgcg taaagaactt aatttggcgc tttacagtcg ttttccatta acgtggatta
    22681 tggaagctgc cgacgacatc tcctattgtg tggcagacct tgaagatgcg gtagagaaaa
    22741 gaatatttac cgttgagcag ctttatcatc atttgcacga agcgtggggc cagcatgaga
    22801 aaggttcgct cttttcgctg gtggttgaaa atgcctggga aaaatcacgc tcaaatagtt
    22861 taagccgcag tacggaagat cagtttttta tgtatttacg ggtaaacacc ctaaataaac
    22921 tggtacccta cgcggcacaa cgatttattg ataatctgcc tgcgattttc gccggaacgt
    22981 ttaatcatgc attattggaa gatgccagcg aatgcagcga tcttcttaag ctatataaaa
    23041 atgtcgctgt aaaacatgtg tttagccatc cggatgtcga gcagcttgaa ttgcagggct
    23101 atcgggtcat tagcggatta ttagagattt atcgtccttt attaagcctg tcgttatcag
    23161 actttactga actggtagaa aaagaacggg tgaaacgttt ccctattgaa tcgcgcttat
    23221 tccacaaact ctcgacgcgc catcggctgg cctatgtcga ggctgtcagt aaattaccgt
    23281 cagattctcc tgagtttccg ctatgggaat attattaccg ttgccgcctg ttgcaggatt
    23341 atatcagcgg tatgaccgac ctctatgcgt gggatgaata ccgacgtctg atggccgtag
    23401 aacaataacc aggcttttgt aaagacgaac aataaatttt taccttttgc agaaacttta
    23461 gttcggaact tcgcgctata aaacgaatct gaagaacaca gcaattttgc gttatctgtt
    23521 aatcgagact gaaatacatg aaaaaaacca cattagcact gagtgcactg gctctgagtt
    23581 taggtttggc gttatctccg ctctctgcaa cggcggctga gacttcttca gcaacgacag
    23641 cccagcagat gccaagcctt gcaccgatgc tcgaaaaggt gatgccttca gtggtcagca
    23701 ttaacgtaga aggtagcaca accgttaata caccgcgtat gccgcgtaat ttccagcagt
    23761 tcttcggtga tgattctccg ttctgccagg aaggttctcc gttccagagc tctccgttct
    23821 gccagggggg ccagggcggt aatggcggcg gccagcaaca aaaattcatg gcgctgggtt
    23881 ccggcgtcat cattgatgcc gataaaggct atgtcgtcac caacaaccat gttgttgata
    23941 acgcgacggt gattaaagtc cagctgagcg atggtcgtaa gttcgacgcg aagatggttg
    24001 gcaaagatcc gcgctctgat atcgcgctga tccaaatcca gaacccgaaa aacctgaccg
    24061 caattaagat ggcggattct gatgcactgc gcgtgggtga ttacaccgta gcgattggta
    24121 acccgtttgg tctgggagag acggtaactt ccgggattgt ctctgcgctg gggcgtagcg
    24181 gcctgaatgc cgaaaactac gaaaacttca tccagaccga tgcagcgatc aaccgtggta
    24241 actccggtgg tgcgctggtt aacctgaacg gcgaactgat cggtatcaac accgcgatcc
    24301 tcgcaccgga cggcggcaac atcggtatcg gttttgctat cccgagcaac atggtgaaaa
    24361 acctgacctc gcagatggtg gaatacggcc aggtgaaacg cggtgagctg ggtattatgg
    24421 ggactgagct gaattccgaa ctggcgaaag cgatgaaagt tgacgcccag cgcggtgctt
    24481 tcgtaagcca ggttctgcct aattcctccg ctgcaaaagc gggcattaaa gcgggtgatg
    24541 tgatcacctc actgaacggt aagccaatca gcagctttgc cgcactgcgt gctcaggtgg
    24601 gtactatgcc ggtgggcagc aaactgaccc tgggcttgct gcgcgacggt aagcaggtca
    24661 acgtgaatct ggaactgcag cagagcagcc agaatcaggt tgattccagc tccatcttca
    24721 acggcattga aggcgctgag atgagcaaca aaggcaaaga tcagggcgtg gtagtgaaca
    24781 acgtgaaaac gggcactccg gctgcgcaga tcggcctgaa gaaaggtgat gtgattattg
    24841 gcgcgaacca gcaggcagtg aaaaacatcg ctgaactgcg taaagtgctc gacagcaaac
    24901 cgtctgtgct ggcactgaac attcagcgcg gcgacagcac catctacctg ttaatgcagt
    24961 aatctccctc aaccccttcc tgaatacggg aaggggttct ccttacaatc tgtgaacttc
    25021 gccacaactc catacatctt catcatcctt tgggcatttg cacaatgccg tacgttacgt
    25081 acttccttat gctaagccgt gcataacgga ggacttatgg ctggctggca tcttgatacc
    25141 aaaatggcgc aggatatcgt ggcacgtacc atgcgcatca tcgataccaa tatcaacgta
    25201 atggatgccc gtgggcgaat tatcggcagc ggcgatcgtg agcgtattgg tgaattgcac
    25261 gaaggtgcat tgctggtact ttcacaggga cgagtcgtcg atatcgatga cgcggtagca
    25321 cgtcatctgc acggtgtgcg gcaggggatt aatctaccgt tacggctgga aggtgaaatt
    25381 gtcggcgtaa ttggcctgac aggtgaacca gagaacctgc gtaaatatgg cgaactggtc
    25441 tgcatgacgg ctgaaatgat gctggaacag tcgcggttga tgcacctgtt ggcgcaggat
    25501 agccgtttgc gggaagaact ggtgatgaac ctgattcagg ctgaggagaa tactcccgca
    25561 cttactgaat gggcgcaacg gctggggatc gatctcaatc aaccgcgagt ggtggctatt
    25621 gttgaggtcg acagcggtca gcttggcgtg gacagcgcaa tggcggagtt acaacaactg
    25681 caaaatgcgc tgactacgcc cgagcgtaat aatctggtgg cgattgtctc gctaaccgaa
    25741 atggtggtgt tgaaaccggc gttgaactct tttgggcgct gggatgcaga agatcatcgt
    25801 aagcgagttg aacaactgat tacccgcatg aaagagtacg gccagttgcg ttttcgcgtt
    25861 tcgctgggca actattttac cggtcctggc agtattgccc gatcctatcg tacggcgaaa
    25921 acgacgatgg tggtgggtaa acagcggatg ccagaaagtc gctgctattt ttatcaggat
    25981 ctgatgttac ctgtgttact cgacagtttg cgtggcgact ggcaggccaa tgaactggcg
    26041 cgaccgctgg cgcggctgaa agcgatggac aataatggct tgctgcgacg aacgctggcg
    26101 gcgtggtttc gccacaatgt gcaaccgctg gctacgtcaa aggcgctgtt tattcatcgt
    26161 aatactctgg agtatcggct taatcgtata tcggaactga ccgggcttga tttgggtaat
    26221 tttgatgaca ggttgctgct gtatgtggcg ttgcagctgg atgaagagcg gtaggttatg
    26281 cgttaaggtc gaggcggcgc tggctcattc ccctcagccc gaagggtaga ggggaatgtc
    26341 cgagttaacc gtcagttcgg cattatttac gcgttagttt ttccagatcg gcttcaatct
    26401 cgctgatctt attggttacg actgactcca ggtgacgtaa gtcgtcgagg atcttacgct
    26461 taagatcaac ttcgctgcgg tcacgctggc agatttgatc aagctcatca atgatatacc
    26521 gtagattcgg gctgatttcc tggacttctt tataaccctg acccacacca tcagcgacga
    26581 ccgttttacg ctgacgcgga tatttaaact taacgctctt ggcgaaaaac tcgcctttgt
    26641 ctttctggaa atagattttc agaatatcgt tgttggcttc ctgccggagg ctgtaacgat
    26701 caatttcttc aggattggta atacccagac ttttcagatt gtcgtacata gcgttacctc
    26761 aaaatgagtc agtaaattgt gcttatttta gcatttggcc tggcccgccc ggctcgactg
    26821 tgatcgcaga aagccttttt cttccagact tctatcatgg cgtaaaaatc aaaaaattac
    26881 ctgctttatt gtggtgatat tccatgggat ggattaacac atttatcttc gttttgcgaa
    26941 ttacatgaca gtccgaaaca agatgaaaaa gtatttaaaa aaggggggaa gaagaatgag
    27001 taggacgaat tattctgagc cagaaagcat acgggcagca tcatgctgcc cgtatatgta
    27061 ctcttaatcg atggtacgca gcagttcgtt aatgccgact ttgccgcgag ttttcgcgtc
    27121 aactttctta acgataaccg cacagtagag gctgtatttg ccatctttcg acggcagatt
    27181 acctgaaaca accacagacc ccgccggaac gcgaccgtag tggatttcgc cggtttcacg
    27241 gtcgtaaata cgggtgctct gaccaatgta tacgcccata gagatgacgg aaccttcttc
    27301 gacaatcacc ccttcaacca cttcggagcg tgcgccaatg aagcagttat cttcaataat
    27361 ggtcgggtta gcctgcagcg gctccagcac gccgccgatg cccacgccac cggaaaggtg
    27421 gacgttttta ccaatctgcg cacaagaacc gacggtcgcc caggtatcaa ccatcgtgcc
    27481 ttcatcaaca tatgcgccga tgttgacgta agacggcatc agcacggtgt tacgggcaat
    27541 aaatgcaccc tgacgtaccg ccgctggtgg cacaacgcgg aagccttctt tctggaaacg
    27601 tgcttcgtcg tagtcggcga atttcatcgg cactttgtcg aagtagcggc tttctgcccc
    27661 ttcgatcacc tgattatcat taatacggaa agagagcagc accgcttttt tcaaccactg
    27721 atgcgtcacc cactgaccgt caattttttc cgctacacgc agtgcaccgg aatccagcag
    27781 ggcgatcacc tgatttaccg cttcgcgggt aacggtgtct gcgttggctg gcgtgatctc
    27841 ggcacggcgt tcaaaagcgg tttcaataat gttctgtaac tgctgcattg ttaaactctt
    27901 ttcatatcag taaacacatc accctttatc gtttggattg agggcctctg tcaaccgctg
    27961 atgcacttcc tgctgcaact cgttattaag tgcacgccgg tcagcggtgg caattatgaa
    28021 taaatcttct actcgctcgc caatggttgt aattcgggca ccatgaagcg aaattcccag
    28081 atcggcaaaa attttcccga ctctcgccag cagtcctggc tggtcgagcg cgataagctc
    28141 aaggaacgat ttgcggtcgg tatgggtcgg caaaaacgtt acttcggttt caacagtaaa
    28201 atggcgtaat ttggcgggtt ggcgacgggg ctgcggtggc tgccagctac tttgcgtcag
    28261 tacttgctcc agaccaaacc gaataacctc atgacgatct gcggacagcg ggctgccatc
    28321 gggttccagc acgataaagg tatccatcgc cataccgtcg cgagtggtga aaatttgtgc
    28381 gtcgtgaaca cttaaattgc ggcggtctaa ttcggcacag acggcggcaa acagataggg
    28441 gcggtccggg ctccagataa aaatctcggt gcctccacgc gtagcctgcg ggctaagcaa
    28501 taccagcggt ttgcttaaat catgctgtaa taaatggcgg gcatgccagg ccagttgatt
    28561 tgggctatgg cggacaaaat agttagcacg acagcgtgac caaatttggt gcagcgcctc
    28621 ttcgtcgatg ttatccatgc gcagtagtgc cagtgcctgg agttggtgat ggcgaacccg
    28681 ttcgcgcata tccggcgtgt tttgcattcc gcgtcgtagc tgcttttcgg tggcaaaata
    28741 gagttcgcgc aacagacttt gcttccagct attccacagc gtttcgttgg tggcgcaaat
    28801 gtcagccact gtcaggcata ccagatagcg cagacgattt tccgtttgaa cttcttcggc
    28861 aaactgcttg atgacttcag ggtcctgaat atcgcggcgt tgtgctgtca ccgacatcag
    28921 caagtgctgg cgaaccagcc aggcaaccag ctgtgtttcg cgtgagttca gcccgtggag
    28981 ttctgcaaaa tgcactacat cctgagcacc gagaatggag tggtcgccgc cgcgtccttt
    29041 ggcgatatcg tgaaacagcg cggcgatgaa aatcagctca gttgacggca ggcgcggcca
    29101 gacgtccaca cacaacggat ggcgctggcg cgtttcttca ctggcaaaac tctccagttt
    29161 cagcatcacg cggatagtat gttcatccac cgtgtaggcg tggaacagat caaactgcat
    29221 ctgcccgacg atatgcgacc attgcggcat atacgcgccg agcacgctat ggcgatgcat
    29281 tggcaatagc ccgcgccgca ccgctccggg gtgacgcaga atgctcaaaa acagttttcg
    29341 tgcttccgga atattacaca gcggttgttg cagatggcga cgggcatggc gtaactggcg
    29401 cagcgtggtg gagtaaatgc cggtgatcgc actgttgcgc accatggtgt agaacatacg
    29461 caagatggct tccggctggc gcataaatag tgtttcatca cgcaggtcga ttagcgtacc
    29521 gcgtagctga aactcatcgt cgagtggacg tggtttttcg tcggcgggaa gggcgaggat
    29581 ggcttcatcg aacagttgca gcagcatctg gttgagttca ctgacgcggc gtgtaacgcg
    29641 gaagtaatcc ttcatcatcc gctcgaccgg ttcgttgcct tcaccactgt aattcagacg
    29701 ctgagcgacg ctaagttggc gatcgaataa cagacgatta tcgtaacggc tgacgaccag
    29761 atgcagggca aagcgaatac gccacagtat atgcagacat tcgtttaatt ccgcccgctc
    29821 cgctgaggtt aagaagccaa acccgaccat ttcatccagc gatgttgcgc caaaatgacg
    29881 gcgggccacc cattgcagag tgtgaatatc gcgcaagccg ccagggctac ttttgatgtc
    29941 tggttcaagg ttgtagctgg tgccatggta acgctgatgg cgctggttct gttcttcaac
    30001 tttcgccgcg tagaacttgt cggaaggcca gaatccttcg ctaaaaatat gtttttgcag
    30061 ttcgaggaag agcgcaacat cgccaattaa taagcgggat tcgattaaat tggtggcgac
    30121 ggttaaatcc gataaccctt ccagcatgca ctcttcaagc gtgcgcacac tatgaccgac
    30181 ttccagcttt acatcccaga gcagcgttaa cagctcgccc actttttgcg cctgatcgtc
    30241 cgggagcttt ttacggctta aaatcagtaa atcgatgtca gaaagtggat gcagctcgcc
    30301 acgaccgtag ccaccgacgg cgaccaatgc caggtcggca atctggctga atcccgcttc
    30361 aatccataat cgttgcagga gctggtcgat aaactcggtg cgcgcctcaa tcaactgttc
    30421 tgcagagatc ccattgtcaa aggcatcacc cagccaacgc tggaaagtat cgatatgggc
    30481 ttttatccca ccgacggtta attcatcacg gggccagacg catggatttt gcggttgacc
    30541 gggcagggtg gggagagcgg tgtttgcgta ctgttctgga agggtattca ttgtgcgcca
    30601 cccataagat taaattatcg cattaaaaaa gccggcattc gccggcttca tcttattcgt
    30661 cgtgcgagat tatcgccggg atggtgtcat ccttgcgtag cgtcaaaatt tcgcagccgt
    30721 tatcagtcac cacaatagta tgctcatatt gtgcagacaa gctgcgatct ttggttttta
    30781 ccgtccagcc atctttcatg gtgcggatct cttttttacc cgcgttgacc attggctcga
    30841 tggtgaacgt catcccaggt ttcagtacga cgttggtttc acgggagtca tagtgcagca
    30901 cctgcggttc ttcatggaag ccgcgaccaa taccgtgtcc gcaatattca cgaacgacgg
    30961 agaagccttc tgcttcgaca aatttctgaa tcgccgcacc gatttcgcgc agattaatgc
    31021 ctggtttgac catgcgcagc gccaggtaca ggctttcttg cgtgatgcgg cacagacgtt
    31081 cgcccatgat ggtcggctta ccgacgataa acattttcga ggtatcgccg tggaaaccat
    31141 ctttgattac ggtgacatca atgttaacga tatcgccatc tttcagcagc ttcgcatcgt
    31201 ccgggatacc gtggcacacc acttcattaa tagagatgca aacggatttc ggatagccgt
    31261 gatagccgag gcaggcagaa accgcgtgtt gttcattaac aatgtaatca ttacagatgc
    31321 gatccagctc gccggtgctg acgcccggtt taacatacgg ttcgatcatc tccagcactt
    31381 cggcagccag tcggccagcg acgcgcattt tttcgatatc ttctggggtc ttgattgaga
    31441 tagccattaa ttctgtccat cagcgtcggt gataccgaca atatatatgt aagtgccgtc
    31501 aatggtatca cacccgggca aattgagaat cattctgaat ttcgccaaac gtgccactga
    31561 aggttttcta taatagaaaa ttcgacatct gatgctgtac acagcgccaa caattattgg
    31621 tgtccatgac gtatttgtgg tataaagcgc gccggacttc cgatccattt cgtatacaca
    31681 gactggacgg aagcgacaat ctcactttgt gtaacaacac acacgtatcg gcacatattc
    31741 cggggtgccc tttggggtcg gtaatatggg atacgtggag gcataacccc aacttttata
    31801 tagaggtttt aatcatggca actgtttcca tgcgcgacat gctcaaggct ggtgttcact
    31861 tcggtcacca gacccgttac tggaacccga aaatgaagcc gttcatcttc ggtgcgcgta
    31921 acaaagttca catcatcaac cttgagaaaa ctgtaccgat gttcaacgaa gctctggctg
    31981 aactgaacaa gattgcttct cgcaaaggta aaatcctttt cgttggtact aaacgcgctg
    32041 caagcgaagc ggtgaaagac gctgctctga gctgcgacca gttcttcgtg aaccatcgct
    32101 ggctgggcgg tatgctgact aactggaaaa ccgttcgtca gtccatcaaa cgtctgaaag
    32161 acctggaaac tcagtctcag gacggtactt tcgaaaagct gaccaagaaa gaagcgctga
    32221 tgcgcactcg tgagctggag aaactggaaa acagcctggg cggtatcaaa gacatgggcg
    32281 gtctgccgga cgctctgttt gtaatcgatg ctgaccacga acacattgct atcaaagaag
    32341 caaacaacct gggtattccg gtatttgcta tcgttgatac caactctgat ccggacggtg
    32401 ttgacttcgt tatcccgggt aacgacgacg caatccgtgc tgtgaccctg tacctgggcg
    32461 ctgttgctgc aaccgtacgt gaaggccgtt ctcaggatct ggcttcccag gcggaagaaa
    32521 gcttcgtaga agctgagtaa taaggcttga taactccccc aaaatagttc gagttgcaga
    32581 aaggcggcaa gctcgagaat tcccgggagc ttacatcagt aagtgaccgg gatgagcgag
    32641 cgaagacaac gcatctgcgg cgcgaaatat gaagggggag agcccttata gaccaggtag
    32701 tacacgtttg gttagggggc ctgcatatgg cccccttttt cacttttata tctgtgcggt
    32761 ttaatgccgg gcagatcaca tctccgagga ttttagaatg gctgaaatta ccgcatccct
    32821 ggtaaaagag ctgcgtgagc gtactggcgc aggcatgatg gattgcaaaa aagcactgac
    32881 tgaagctaac ggcgacatcg agctggcaat cgaaaacatg cgtaagtccg gtgctattaa
    32941 agcagcgaaa aaagcaggca acgttgctgc tgacggcgtg atcaaaacca aaatcgacgg
    33001 caactacggc atcattctgg aagttaactg ccagactgac ttcgttgcaa aagacgctgg
    33061 tttccaggcg ttcgcagaca aagttctgga cgcagctgtt gctggcaaaa tcactgacgt
    33121 tgaagttctg aaagcacagt tcgaagaaga acgtgttgcg ctggtagcga aaattggtga
    33181 aaacatcaac attcgccgcg ttgctgcgct ggaaggcgac gttctgggtt cttatcagca
    33241 cggtgcgcgt atcggcgttc tggttgctgc taaaggcgct gacgaagagc tggttaaaca
    33301 catcgctatg cacgttgctg caagcaagcc agaattcatc aaaccagaag acgtatccgc
    33361 tgaagtggta gaaaaagaat accaggtaca gctggatatc gcgatgcagt ctggtaagcc
    33421 gaaagaaatc gcagagaaaa tggttgaagg ccgcatgaag aaattcaccg gcgaagtttc
    33481 tctgaccggt cagccgttcg ttatggaacc aagcaaaact gttggtcagc tgctgaaaga
    33541 gcataacgct gaagtgactg gcttcatccg cttcgaagtg ggtgaaggca tcgagaaagt
    33601 tgagactgac tttgcggcag aagttgctgc gatgtccaag cagtcttaat tatcaaaaag
    33661 gagccgcctg agggcggctt ctttttgtgc ccatcttgta aattcagcta acccttgtgg
    33721 ggctgcgctg aaaagcgacg tacaatgtcg ctagtattaa ttcatttcaa tcgttgacag
    33781 tctcaggaaa gaaacatggc taccaatgca aaacccgtct ataaacgcat tctgcttaag
    33841 ttgagtggcg aagctctgca gggcactgaa ggcttcggta ttgatgcaag catactggat
    33901 cgtatggctc aggaaatcaa agaactggtt gaactgggta ttcaggttgg tgtggtgatt
    33961 ggtgggggta acctgttccg tggcgctggt ctggcgaaag cgggtatgaa ccgcgttgtg
    34021 ggcgaccaca tggggatgct ggcgaccgta atgaacggcc tggcaatgcg tgatgcactg
    34081 caccgcgcct atgtgaacgc tcgtctgatg tccgctattc cattgaatgg cgtgtgcgac
    34141 agctacagct gggcagaagc tatcagcctg ttgcgcaaca accgtgtggt gatcctctcc
    34201 gccggtacag gtaacccgtt ctttaccacc gactcagcag cttgcctgcg tggtatcgaa
    34261 attgaagccg atgtggtgct gaaagcaacc aaagttgacg gcgtgtttac tgctgatccg
    34321 gcgaaagatc caactgcaac catgtacgag caactgactt acagcgaagt gctggaaaaa
    34381 gagctgaaag tcatggacct ggcggccttc acgctggctc gtgaccataa attaccgatt
    34441 cgtgttttca acatgaacaa accgggtgcg ctgcgccgtg tggtaatggg tgaaaaagaa
    34501 gggactttaa tcacggaata attcccgtga tggataaata agggtaagat tccgcataag
    34561 tatcgcgggg cgtaagtctg gttataaggc gttattgttg caggcagttt ggtcacggcc
    34621 agcgcgcagc aaccggtgcg tacacaagta cgtgaggatg gcgagcacta cccggggcca
    34681 aaatggcaaa taaaatagcc taataatcca gacgattacc cgtaatatgt ttaatcaggg
    34741 ctatacttag cacacttcca ctgtgtgtga ctgtctggtc tgactgagac aagttttcaa
    34801 ggattcgtaa cgtgattagc gatatcagaa aagatgctga agtacgcatg gacaaatgcg
    34861 tagaagcgtt caaaacccaa atcagcaaaa tacgcacggg tcgtgcttct cccagcctgc
    34921 tggatggcat tgtcgtggaa tattacggca cgccgacgcc gctgcgtcag ctggcaagcg
    34981 taacggtaga agattcccgt actctgaaaa tcaacgtgtt tgatcgttca atgtctccgg
    35041 ccgttgaaaa agcgattatg gcgtccgatc ttggcctgaa cccgaactct gcgggtagcg
    35101 acatccgtgt tccgctgccg ccgctgacgg aagaacgtcg taaagatctg accaaaatcg
    35161 ttcgtggtga agcagaacaa gcgcgtgttg cagtacgtaa cgtgcgtcgt gacgcgaacg
    35221 acaaagtgaa agcactgttg aaagataaag agatcagcga agacgacgat cgccgttctc
    35281 aggacgatgt acagaaactg actgatgctg caatcaagaa aattgaagcg gcgctggcag
    35341 acaaagaagc agaactgatg cagttctgat ttcttgaacg acaaaaacgc cgctcagtag
    35401 atccttgcgg atcggctggc ggcgttttgc tttttattct gtctcaactc tggatgtttc
    35461 atgaagcaac tcaccattct gggctcgacc ggctcgattg gttgcagcac gctggacgtg
    35521 gtgcgccata atcccgaaca cttccgcgta gttgcgctgg tggcaggcaa aaatgtcact
    35581 cgcatggtag aacagtgcct ggaattctct ccccgctatg ccgtaatgga cgatgaagcg
    35641 agtgcgaaac ttcttaaaac gatgctacag caacagggta gccgcaccga agtcttaagt
    35701 gggcaacaag ccgcttgcga tatggcagcg cttgaggatg ttgatcaggt gatggcagcc
    35761 attgttggcg ctgctgggct gttacctacg cttgctgcga tccgcgcggg taaaaccatt
    35821 ttgctggcca ataaagaatc actggttacc tgcggacgtc tgtttatgga cgccgtaaag
    35881 cagagcaaag cgcaattgtt accggtcgat agcgaacata acgccatttt tcagagttta
    35941 ccgcaaccta tccagcataa tctgggatac gctgaccttg agcaaaatgg cgtggtgtcc
    36001 attttactta ccgggtctgg tggccctttc cgtgagacgc cattgcgcga tttggcaaca
    36061 atgacgccgg atcaagcctg ccgtcatccg aactggtcga tggggcgtaa aatttctgtc
    36121 gattcggcta ccatgatgaa caaaggtctg gaatacattg aagcgcgttg gctgtttaac
    36181 gccagcgcca gccagatgga agtgctgatt cacccgcagt cagtgattca ctcaatggtg
    36241 cgctatcagg acggcagtgt tctggcgcag ctgggggaac cggatatgcg tacgccaatt
    36301 gcccacacca tggcatggcc gaatcgcgtg aactctggcg tgaagccgct cgatttttgc
    36361 aaactaagtg cgttgacatt tgccgcaccg gattatgatc gttatccatg cctgaaactg
    36421 gcgatggagg cgttcgaaca aggtcaggca gcgacgacag cattgaatgc cgcaaacgaa
    36481 atcaccgttg ctgcttttct tgcgcaacaa atccgcttta cggatatcgc tgcgttgaat
    36541 ttatccgtac tggaaaaaat ggatatgcgc gaaccacaat gtgtggacga tgtgttatct
    36601 gttgatgcga acgcgcgtga agtcgccaga aaagaggtga tgcgtctcgc aagctgagga
    36661 taatccggct acagagagtc gcgctatttg ttagcgtagg gcttcagtga tatagtctgc
    36721 gccatctgat cgtaagtagt tggctttata aggtcaggta tgccgtggtt ttacacggct
    36781 tttttttgta taggcttcag tattcctgag taccgtaaac cctgtcaggg aataaaaaac
    36841 gcgtgatgtt gtctgctact caaccactta gcgaaaaatt gccagcgcat ggctgccgtc
    36901 atgttgcgat cattatggac ggcaatggtc gctgggcaaa aaagcaaggg aagattcgtg
    36961 cctttgggca taaagccggg gcaaaatccg tccgccgggc tgtctctttt gcggccaaca
    37021 acggtattga ggcgttaacg ctgtatgcct ttagtagtga aaactggaac cgaccagcgc
    37081 aggaagtcag tgcgttaatg gaactgtttg tgtgggcgct cgatagcgaa gtaaaaagtc
    37141 tgcaccgaca taacgtgcgt ctgcgtatta ttggcgatac cagtcgcttt aactcgcgtt
    37201 tgcaagaacg tattcgtaaa tctgaagcgc taacagccgg gaataccggt ctgacgctga
    37261 atattgcggc gaactacggt ggacgttggg atatagtcca gggagtcaga caactggctg
    37321 aaaaggtgca gcaaggaaac ctgcaaccag atcagataga tgaagagatg ctaaaccagc
    37381 atgtctgtat gcatgaactg gcccctgtag atttagtaat taggactggg ggggagcatc
    37441 gcattagtaa ctttttgctt tggcaaattg cctatgccga actttacttt acagatgttc
    37501 tctggcccga tttcgatgaa caagactttg aaggggcgtt aaatgccttt gctaatcgag
    37561 agcgtcgttt cggcggcacc gagcccggtg atgaaacagc ctgatggggg tcgcttttgc
    37621 tgaagtatcg cctgatatct gcttttgtgt taatacccgt cgtcatcgcg gcgttgtttc
    37681 tgttgccgcc ggtggggttc gccatcgtaa cgctggtggt ctgcatgctg gcagcgtggg
    37741 aatggggaca gcttagcggt tttaccactc gttcgcagcg agtatggttg gcggtgttat
    37801 gcgggttatt gttggcgctg atgctttttc tgttgccgga atatcaccga aatattcatc
    37861 aaccgctggt tgaaatctca ctttgggctt cgctgggttg gtggattgtc gcgctattgc
    37921 tggtgctgtt ttacccaggt tccgcagcaa tctggcgtaa ctctaaaaca ttgcgcctta
    37981 tttttggcgt gctaaccatt gttcccttct tctggggcat gctggcgtta cgggcctggc
    38041 actacgacga gaatcattac agtggcgcaa tatggctgct ctatgtcatg atcctggtat
    38101 ggggcgctga ctctggcgca tatatgtttg gcaaattgtt tggtaaacat aagctggcac
    38161 cgaaggtttc tccgggtaaa acctggcaag gctttatagg tggactagcg accgcagcgg
    38221 taatctcatg gggttatggc atgtgggcga atctcgacgt cgctcccgtc accttactca
    38281 tttgctctat tgtcgcagcg ttagcctcag tgctcggcga tctgaccgag agtatgttta
    38341 agcgtgaagc aggaattaag gacagcggtc atttaattcc aggacacggt ggtattttag
    38401 atcgtattga tagcctgacg gctgcggtac cggtctttgc ttgcttgttg ttactggtat
    38461 tcaggacgct ttaacggaag gtaatatgct gagttttctc tgggatttgg cttcgttcat
    38521 cgttgcactg ggtgtactta tcaccgtgca tgaatttggt catttctggg ttgcccggcg
    38581 ttgtggtgtt cgcgttgagc gtttctcaat agggtttggt aaggcgctct ggcggcgaac
    38641 tgataagctc ggcaccgaat atgttatcgc cctgatcccg ctgggcggtt atgtcaaaat
    38701 gctggatgag cgcgcagaac cggtcgttcc ggaactccgc caccatgcct tcaataataa
    38761 atctgttggc caacgagcgg cgattattgc cgcaggtccg gttgcaaact tcatttttgc
    38821 tatctttgcc tactggctgg tttttattat tggtgtgcct ggcgtacgtc cggtggttgg
    38881 tgaaatagca gccaattcga tagctgcgga agcacaaatt gcaccaggta cggaactaaa
    38941 agccgtagat ggtatcgaaa cgcctgattg ggatgccgtg cgtttgcagt tggtcgataa
    39001 aattggcgat gaaagcacca ccattacagt agcgccattt ggcagcgatc aacggcggga
    39061 tgtaaagctc gatttacgtc actgggcgtt tgagcctgat aaagaagatc cggtatcttc
    39121 gctggggatt cgtcctcgtg ggccgcaaat tgaacctgta ctggaaaatg tgcagccaaa
    39181 ctcggcggca agcaaggcag gtttgcaagc aggcgacagg atcgttaaag tcgatggtca
    39241 gcccttaacg cagtgggtga cctttgtgat gcttgtccgg gataacccgg gtaaatcctt
    39301 agcgttagaa atcgaaaggc agggaagtcc cttgtctttg acattaatcc cggagagtaa
    39361 accgggtaat ggtaaagcga ttggttttgt cggtattgag ccgaaagtca ttcctttgcc
    39421 agatgagtat aaagttgtac gccagtatgg gccgttcaac gccatcgtcg aagccacgga
    39481 caaaacgtgg cagctgatga agctgacggt cagtatgctg ggaaaattga tcaccggtga
    39541 tgtgaaactg aacaacctca gtgggccgat ctctatcgcc aagggggctg ggatgacagc
    39601 ggaactcggg gtagtttatt acctgccgtt tcttgcgctt attagcgtga acttagggat
    39661 aattaacctg tttccgttgc ccgtacttga cggggggcat ctgctgttcc ttgcgatcga
    39721 aaagatcaag ggcggaccgg tatccgagcg ggttcaagac ttttgttatc gcattggctc
    39781 gattctgctg gtgctgttaa tggggcttgc acttttcaat gatttctctc ggttatgaga
    39841 gttagttagg aagaacgcat aataacgatg gcgatgaaaa agttgctcat agcgtcgctg
    39901 ctgtttagca gcgccaccgt atacggtgct gaagggttcg tagtgaaaga tattcatttc
    39961 gaaggccttc agcgtgtcgc cgttggtgcg gccctcctca gtatgccggt gcgcacaggc
    40021 gacacggtta atgatgaaga tatcagtaat accattcgcg ctctgtttgc taccggcaac
    40081 tttgaggatg ttcgcgtcct tcgtgatggt gatacccttc tggttcaggt aaaagaacgt
    40141 ccgaccattg ccagcattac tttctccggt aacaaatcgg tgaaagatga catgctgaag
    40201 caaaacctcg aggcttctgg tgtgcgtgtg ggcgaatccc tcgatcgcac caccattgcc
    40261 gatatcgaga aaggtctgga agacttctac tacagcgtcg gtaaatatag cgccagcgta
    40321 aaagctgtcg tgaccccgct gccgcgcaac cgtgttgacc taaaactggt gttccaggaa
    40381 ggtgtgtcag ctgaaatcca gcaaattaac attgttggta accatgcttt caccaccgac
    40441 gaactgatct ctcatttcca actgcgtgac gaagtgccgt ggtggaacgt ggtaggcgat
    40501 cgtaaatacc agaaacagaa actggcgggc gaccttgaaa ccctgcgcag ctactatctg
    40561 gatcgcggtt atgcccgttt caacatcgac tctacccagg tcagtctgac gccagataaa
    40621 aaaggtattt acgtcacggt gaacatcacc gaaggcgatc agtacaagct ttctggcgtt
    40681 gaagtgagcg gcaaccttgc cgggcactcc gctgaaattg agcagctgac taagatcgag
    40741 ccgggtgagc tgtataacgg caccaaagtg accaagatgg aagatgacat caaaaagctt
    40801 ctcggtcgct atggttatgc ctatccgcgc gtacagtcga tgcctgaaat taacgatgcc
    40861 gacaaaaccg ttaaattacg cgtgaacgtt gatgcgggta accgtttcta cgtgcgtaag
    40921 atccgttttg aaggtaacga tacctcgaaa gatgccgtcc tgcgtcgcga aatgcgtcag
    40981 atggaaggtg catggctggg aagcgatctg gtcgatcagg gtaaggagcg tctgaatcgt
    41041 ctgggcttct ttgaaactgt cgataccgat acccaacgtg ttccgggtag cccggaccag
    41101 gtagatgtcg tctacaaggt aaaagagcgc aacaccggta gcttcaactt tggtattggt
    41161 tacggtactg aaagtggcgt gagcttccag gctggtgtgc agcaggataa ctggttaggt
    41221 acaggttatg ctgttggtat caacgggacc aaaaacgatt accagaccta tgctgaactg
    41281 tcggtaacca acccgtactt cactgtagat ggtgtaagcc tcggtggtcg tctcttctat
    41341 aatgacttcc aggcagatga cgccgacctg tccgactata ccaacaagag ttatggtaca
    41401 gacgtgacgt tgggcttccc gatcaacgaa tataactcgc tgcgtgcagg tctgggttat
    41461 gtacataact ccctgtccaa catgcagcct caggttgcga tgtggcgtta tctgtactct
    41521 atgggtgaac atccgagcac ctctgatcag gataatagct tcaaaacgga cgacttcacg
    41581 ttcaactatg gttggaccta taacaagctt gaccgtggtt acttcccgac agatggttca
    41641 cgtgtcaacc tgaccggtaa agtgaccatt cctggatcgg ataacgaata ctacaaagtg
    41701 acgttagaca cggcgactta tgtgccgatc gatgacgatc acaaatgggt tgttctgggg
    41761 cgtacccgct ggggttatgg tgatggttta ggcggcaaag agatgccgtt ctacgagaac
    41821 ttctatgccg gtggttccag caccgtgcgt ggcttccagt ccaatacaat tggtccgaaa
    41881 gcagtttact tcccgcatca ggccagtaat tatgatccgg actatgatta cgaatgtgcg
    41941 actcaggacg gcgcgaaaga cctgtgtaaa tcggatgatg ctgtaggcgg taacgccatg
    42001 gcggttgcca gcctcgagtt catcaccccg acgccgttta ttagcgataa gtatgctaac
    42061 tcggttcgta cttccttctt ctgggatatg ggtaccgttt gggatacaaa ctgggattcc
    42121 agccaatatt ctggatatcc ggactatagt gatccaagca atatccgtat gtctgcgggt
    42181 atcgcattac aatggatgtc cccattgggg ccgttggtgt tctcctacgc ccagccgttc
    42241 aaaaagtacg atggagacaa ggcagaacag ttccagttta acatcggtaa aacctggtaa
    42301 gtgttctcca caaaggaatg tagtggtagt gtagcgatga ctttaggcga tcaatataag
    42361 atcgccgggc cacgcaaaga actgcaccct ccggtgcaaa tgggatggta aggagtttat
    42421 tgtgaaaaag tggttattag ctgcaggtct cggtttagca ctggcaactt ctgctcaggc
    42481 ggctgacaaa attgcaatcg tcaacatggg cagcctgttc cagcaggtag cgcagaaaac
    42541 cggtgtttct aacacgctgg aaaatgagtt caaaggccgt gccagcgaac tgcagcgtat
    42601 ggaaaccgat ctgcaggcta aaatgaaaaa gctgcagtcc atgaaagcgg gcagcgatcg
    42661 cactaagctg gaaaaagacg tgatggctca gcgccagact tttgctcaga aagcgcaggc
    42721 ttttgagcag gatcgcgcac gtcgttccaa cgaagaacgc ggcaaactgg ttactcgtat
    42781 ccagactgct gtgaaatccg ttgccaacag ccaggatatc gatctggttg ttgatgcaaa
    42841 cgccgttgct tacaacagca gcgatgtaaa agacatcact gccgacgtac tgaaacaggt
    42901 taaataagta atgccttcaa ttcgactggc tgatttagcg cagcagttgg atgcagaact
    42961 acacggtgat ggcgatatcg tcatcaccgg cgttgcgtcc atgcaatctg cacaaacagg
    43021 tcacattacg ttcatggtta acccaaaata ccgtgagcat ttaggcttgt gccaggcgtc
    43081 cgcggttgtc atgacccagg acgatcttcc tttcgcgaaa agtgccgcgc tggtagtgaa
    43141 gaatccctac ctgacttacg cgcgcatggc gcaaatttta gataccacgc cgcagcccgc
    43201 gcagaacatt gcacccagtg cggtgatcga cgcgacggcg aagctgggta acaacgtatc
    43261 gattggcgct aacgcggtga ttgagtccgg cgttgaactg ggcgataacg tgattatcgg
    43321 tgccggttgc ttcgtaggta ataacagcaa aatcggtgca ggttcgcgtc tctgggcgaa
    43381 cgtaaccatt taccatgaga tccagatcgg tcagaattgc ctgatccagt ccggaacagt
    43441 ggtaggcgca gacggctttg gttatgccaa cgatcgtggt aactgggtga agatcccaca
    43501 gattggtcgc gtaattattg gcgatcgcgt ggagatcggt gcctgcacaa ccatcgatcg
    43561 cggcgcgctg gatgacacta ttattggcaa tggcgtgatc attgataacc agtgccagat
    43621 tgcacataac gtcgtgattg gcgacaatac ggcggttgcc ggtggcgtca ttatggcggg
    43681 cagcctgaaa attggtcgtt actgcatgat cggcggagcc agcgtaatca acgggcatat
    43741 ggaaatatgc gacaaagtga cggttacggg catgggtatg gtgatgcgtc ccatcactga
    43801 accaggcgtc tattcctcag gcattccgct gcaacccaac aaagtctggc gcaaaaccgc
    43861 tgcactggtg atgaacattg atgacatgag caagcgtctg aaatcgcttg agcgcaaggt
    43921 taatcaacaa gactaacgtt ccatcttttg ttcgccaaac tttacggcct gtctcattct
    43981 tacgattgcg gcaggccgtg ttattattgt cgtttcttat attttgacag gaagagtatc
    44041 ttgactacta acactcatac tctgcagatt gaagagattt tagaacttct gccgcaccgt
    44101 ttcccgttct tactggtgga tcgcgtgctg gattttgaag aaggtcgttt tctgcgcgca
    44161 gtaaaaaatg tctctgtcaa tgagccattc ttccagggcc atttccctgg aaaaccgatt
    44221 ttcccgggtg tgctgattct ggaagcaatg gcacaggcaa caggtattct ggcgtttaaa
    44281 agcgtaggaa aactggaacc gggtgagctg tactacttcg ctggtattga cgaagcgcgc
    44341 ttcaagcgcc cggtcgtgcc tggcgatcaa atgatcatgg aagtcacttt cgaaaaaacg
    44401 cgccgcggcc tgacccgttt taaaggggtt gctctggtcg atggtaaagt agtttgcgaa
    44461 gcaacgatga tgtgtgctcg tagccgggag gcctgatacg tgattgataa atccgccttt
    44521 gtgcatccaa ccgccattgt ggaagagggc gcgtcaattg gcgcgaacgc acacattggt
    44581 cctttttgta tcgttggacc ccatgtcgaa attggtgagg gtaccgtact gaaatctcac
    44641 gttgtcgtga atggtcatac taaaattggc cgcgataatg agatttatca gttcgcctcc
    44701 atcggcgaag ttaaccagga tctgaaatat gctggcgaac cgacccgtgt ggaaatcggc
    44761 gatcgtaacc gcattcgcga aagcgtcacc attcatcgtg gcacagtcca gggcggtgga
    44821 ttgacgaagg tgggcagcga caacttactg atgatcaacg cgcacattgc gcacgattgt
    44881 acggtaggta accgctgtat tctcgccaac aacgcaacgc tggcgggtca cgtatcggtt
    44941 gacgacttcg cgatcatcgg cggcatgacc gcagtccatc agttctgcat cattggtgcg
    45001 cacgtgatgg ttggcggctg ctccggtgtg gcgcaggacg tccctcctta tgtcattgcg
    45061 cagggtaacc acgcaacgcc gttcggtgtc aatatcgaag ggctgaagcg ccgcggattc
    45121 agccgtgagg cgattaccgc tatccgcaat gcgtataagc tgatttatcg tagcggtaaa
    45181 acgctcgatg aagtgaaacc ggaaattgct gaactggcgg aaacatatcc ggaagtgaaa
    45241 gcctttaccg atttctttgc acgctcaacg cgcggtctga ttcgttaatg actgaacagc
    45301 gtccattaac gattgccctg gtcgccggag aaacctccgg cgatatcctg ggggccggtt
    45361 taatccgcgc tctgaaagaa cgtgtgccca acgcccgctt tgttggtgtt gccgggccac
    45421 gaatgcaggc tgaaggctgc gaagcctggt acgaaatgga agaactggcg gtaatgggca
    45481 ttgttgaagt gctcggtcgt ctgcgtcgct tactgcatat tcgtgccgat ctgacaaagc
    45541 gttttggcga actgaagcca gatgtttttg ttggtattga tgcgcccgac ttcaatatta
    45601 ctcttgaagg taacctcaaa aagcagggta tcaaaaccat tcattacgtc agtccatccg
    45661 tctgggcgtg gcgacagaaa cgcgttttca aaataggcag agccaccgat ctggtgctcg
    45721 catttctgcc tttcgaaaaa gcgttttatg acaaatacaa tgtaccgtgc cgctttatcg
    45781 gtcataccat ggctgatgcc atgccgttag atccagataa aaatgccgcc cgtgatgtgc
    45841 tggggatccc tcacgatgcc cactgcctgg cgttgctacc ggggagccgt ggcgcagaag
    45901 ttgaaatgct tagtgccgat ttcctgaaaa cggcccagct tttgcgccag acatatccgg
    45961 atctcgaaat cgtggtgcca ctggtgaatg ccaaacgccg cgagcagttt gaacgcatca
    46021 aagctgaagt cgcgccagac ctttcagttc atttgctgga tgggatgggc cgtgaggcga
    46081 tggtcgccag cgatgcggcg ctactggcgt cgggtacggc agccctggag tgtatgctgg
    46141 cgaaatgccc gatggtggtg ggatatcgca tgaagccttt taccttctgg ttggcgaagc
    46201 ggctggtgaa aactgattat gtctcgctgc caaatctgct ggcgggcaga gagttagtca
    46261 aagaattatt gcaggaagag tgtgagccgc aaaaactggc tgcggcgctg ttaccgctgt
    46321 tggcgaacgg gaaaaccagc cacgcgatgc acgatacctt ccgtgaactg catcagcaga
    46381 tccgctgcaa tgccgatgag caggcggcac aagccgttct ggagttagca caatgatcga
    46441 atttgtttat ccgcacacgc agctggttgc gggtgtggat gaagtcggac gcgggccgtt
    46501 agttggcgcg gtcgtcaccg ctgcggtgat ccttgacccg gcgcgcccga ttgccgggct
    46561 gaatgattcc aaaaagctga gcgaaaaacg ccgtctggcg ctctatgaag agatcaaaga
    46621 gaaagcgttg agctggagtc tgggccgcgc ggaaccccac gaaatcgacg agctgaacat
    46681 tcttcatgcg accatgctgg cgatgcagcg tgccgtcgct gggctgcata ttgcgccgga
    46741 atatgtgttg attgatggta accgctgccc gaaattaccg atgcctgcga tggctgtggt
    46801 gaaaggcgat agccgcgtac cggaaatcag tgccgcgtct atcctggcga aagtgacgcg
    46861 tgacgccgaa atggcggcgc tggatattgt tttcccgcaa tatggttttg cccaacacaa
    46921 agggtaccca accgcttttc atctggaaaa actggctgaa cacggcgcga ccgaacacca
    46981 tcggcgcagc tttgggcctg tcaaacgcgc actgggactt gcgtcctgat tcttgtgtcg
    47041 agattaagta aaccggaatc tgaagatgtc tgaaccacgt ttcgtacacc tgcgggtgca
    47101 cagcgactac tcgatgatcg atggcctggc caaaaccgca ccgctggtaa aaaaggcggc
    47161 ggcgttgggt atgccagcac tggcgatcac cgatttcacc aacctttgcg gtctggtgaa
    47221 gttctacgga gcgggacatg gcgcagggat taagcctatc gtcggggcag attttaacgt
    47281 ccagtgcgac ctgctgggtg atgagttaac ccacctgacg gtactggcgg cgaacaatac
    47341 cggctatcag aatctgacgt tgctgatctc aaaagcgtat cagcgcgggt acggtgccgc
    47401 cgggccgatc atcgatcgcg actggcttat cgaattaaac gaagggttga tccttctttc
    47461 cggcggacgc atgggcgacg tcggacgcag tcttttgcgt ggtaacagcg cgctggtaga
    47521 tgagtgtgtc gcgttttatg aagaacactt cccggatcgc tattttctcg agctgatccg
    47581 caccggcagg ccggacgaag aaagctatct gcacgcggcg gtggaactgg cggaagcgcg
    47641 cggtttgccc gtcgtggcga ccaacgacgt gcgctttatc gacagcagcg actttgacgc
    47701 acacgaaatc cgcgtcgcga tccacgacgg ctttaccctc gacgatccta aacgcccgcg
    47761 taactattcg ccgcagcaat atatgcgtag cgaagaggag atgtgtgagc tgtttgccga
    47821 catccccgaa gcccttgcca acaccgttga gatcgccaaa cgctgtaacg taaccgtgcg
    47881 tcttggtgaa tacttcctgc cgcagttccc gaccggggac atgagcaccg aagattatct
    47941 ggtcaagcgt gcaaaagagg gcctggaaga gcgtctggcc tttttattcc ctgatgagga
    48001 agaacgtctt aagcgccgcc cggaatatga cgaacgtctg gagactgaac ttcaggttat
    48061 caaccagatg ggcttcccgg gctacttcct catcgttatg gaatttatcc agtggtcgaa
    48121 agataacggc gtaccggtag ggccaggccg tggctccggt gcgggttcac tggtggccta
    48181 cgcgctgaaa atcaccgacc tcgatccgct ggaatttgac ctgctgttcg aacgtttcct
    48241 taacccggaa cgtgtctcca tgcctgactt cgacgttgac ttctgtatgg agaaacgcga
    48301 tcaggttatc gaacacgtgg cggacatgta cggtcgtgat gcggtatcgc agatcatcac
    48361 cttcggtaca atggcggcga aagcggtgat ccgcgacgta ggccgcgtgc tggggcatcc
    48421 gtacggcttt gtcgatcgta tctcgaaact gatcccgccc gatccgggga tgacgctggc
    48481 gaaagcgttt gaagccgagc cgcagttgcc ggaaatctac gaagcggatg aagaagttaa
    48541 ggcgctgatc gacatggcgc gcaaactgga aggggtcacc cgtaacgccg gtaagcacgc
    48601 cggtggggtg gttatcgcgc cgaccaaaat taccgatttt gcgccgcttt actgcgatga
    48661 agagggcaaa catccggtca cccagtttga taaaagcgac gttgaatacg ccggactggt
    48721 gaagttcgac ttccttggtt tgcgtacgct caccatcatc aactgggcgc tggagatgat
    48781 caacaagcgg cgggcgaaga atggcgagcc gccgctggat atcgccgcga tcccgctgga
    48841 tgacaagaaa agcttcgaca tgctgcaacg ctcggaaacc acggcggtat tccagcttga
    48901 atcgcgcggc atgaaggacc tgatcaagcg tctgcaacct gactgcttcg aagatatgat
    48961 cgcactggtg gcgctgttcc gcccaggtcc gttgcaatca gggatggtgg ataactttat
    49021 cgaccgtaaa catggtcgcg aagaaatctc ctatccggac gtacagtggc agcatgaaag
    49081 cctgaaaccg gtactggagc caacctacgg catcatcctg tatcaggaac aggtcatgca
    49141 gattgcgcag gtgctttctg gttataccct cggtggcgcg gatatgctgc gtcgtgcgat
    49201 gggtaagaaa aagccggaag agatggctaa gcagcgttct gtatttgctg aaggtgcaga
    49261 aaagaacgga atcaacgccg aactggcgat gaaaatcttc gacctggtgg agaaattcgc
    49321 gggttacgga tttaacaaat cgcactctgc ggcctatgct ttggtgtcat atcaaacgtt
    49381 atggctgaaa gcgcactatc cggcggagtt tatggcggcg gtaatgaccg ccgatatgga
    49441 caacaccgag aaggtggtgg gcctggtgga tgagtgctgg cggatggggc tgaaaatcct
    49501 gccaccagat ataaactccg gtctttacca tttccacgtc aacgacgacg gcgaaatcgt
    49561 gtatggtatt ggcgccatca aaggggtagg tgaaggtccg attgaggcca tcatcgaagc
    49621 ccgtaataaa ggcggctact tccgcgaact gtttgatctc tgcgcccgta ccgacaccaa
    49681 aaagttaaac cggcgggtgc tggaaaaact gatcatgtcc ggggcgtttg accgtcttgg
    49741 gccacaccgc gcggcgctga tgaactcgct gggtgatgcg ttaaaagcgg cagatcaaca
    49801 cgcgaaagcg gaagctatcg gtcaggccga tatgttcggc gtgctggccg aagagccgga
    49861 acaaattgaa caatcctacg ccagctgcca accgtggccg gagcaggtgg tattagatgg
    49921 ggaacgtgaa acgttaggcc tgtacctgac cggacaccct atcaaccagt atttaaaaga
    49981 gattgagcgt tatgtcggag gcgtaaggct gaaagacatg cacccgacag aacgtggtaa
    50041 agtcatcacg gctgcggggc tcgttgttgc cgcgcgggtt atggtcacca agcgcggcaa
    50101 tcgtatcggt atctgcacgc tggatgaccg ttccgggcgg ctggaagtga tgttgtttac
    50161 tgacgccctg gataaatacc agcaattgct ggaaaaagac cgcatactta tcgtcagcgg
    50221 acaggtcagc tttgatgact tcagcggtgg gcttaaaatg accgctcgcg aagtgatgga
    50281 tattgacgaa gcccgggaaa aatatgctcg cgggcttgct atctcgctga cggacaggca
    50341 aattgatgac cagcttttaa accgactccg tcagtctctg gaaccccacc gctctgggac
    50401 aattccagta catctctact atcagagggc ggatgcacgc gcgcggttgc gttttggcgc
    50461 gacgtggcgt gtctctccga gcgatcgttt attaaacgat ctccgtggcc tcattggttc
    50521 ggagcaggtg gaactggagt ttgactaata caggaatact atgagtctga atttccttga
    50581 ttttgaacag ccgattgcag agctggaagc gaaaatcgat tctctgactg cggttagccg
    50641 tcaggatgag aaactggata ttaacatcga tgaagaagtg catcgtctgc gtgaaaaaag
    50701 cgtagaactg acgcgtaaaa tcttcgccga tcttggtgca tggcagattg cgcaactggc
    50761 acgccatcca cagcgtcctt ataccctgga ttacgttcgc ctggcatttg atgaatttga
    50821 cgaactggct ggcgaccgcg cgtatgcaga cgataaagct atcgtcggtg gtatcgcccg
    50881 tctcgatggt cgtccggtga tgatcattgg tcatcaaaaa ggtcgtgaaa ccaaagaaaa
    50941 aattcgccgt aactttggta tgccagcgcc agaaggttac cgcaaagcac tgcgtctgat
    51001 gcaaatggct gaacgcttta agatgccaat catcaccttt atcgacaccc cgggggctta
    51061 tccgggcgtg ggcgcagaag aacgtggtca gtctgaagcc attgcacgca acctgcgtga
    51121 aatgtctcgc ctcggcgtac cggtagtttg tacggttatc ggtgaaggtg gttctggcgg
    51181 tgcgctggcg attggcgtgg gcgataaagt gaatatgctg caatacagca cctattccgt
    51241 tatctcgccg gaaggttgtg cgtccattct gtggaagagc gccgacaaag cgccgctggc
    51301 ggctgaagcg atgggtatca tcgctccgcg tctgaaagag ctgaaactga tcgactccat
    51361 catcccggaa ccgctgggtg gcgctcaccg taacccggaa gcgatggcgg catcgttgaa
    51421 agcgcaactg ctggcggatc tggccgatct cgatgtgtta agcactgaag atttaaaaaa
    51481 tcgtcgttat cagcgcctga tgagctacgg ttacgcgtaa ttcgcaaaag ttctgaaaaa
    51541 gggtcacttc ggtggccctt ttttatcgcc acggtttgag caggctatga ttaaggaagg
    51601 attttccagg aggaacacat gaacatcatt gccattatgg gaccgcatgg cgtcttttat
    51661 aaagatgagc ccatcaaaga actggagtcg gcgctggtgg cgcaaggctt tcagattatc
    51721 tggccacaaa acagcgttga tttgctgaaa tttatcgaac ataaccctcg aatttgcggc
    51781 gtgatttttg actgggatga gtacagtctc gatttatgca gcgatatcaa tcaacttaat
    51841 gaatatctcc cgctttatgc cttcatcaac acccactcga cgatggatgt cagcgtgcag
    51901 gatatgcgga tggcgctctg gttttttgaa tatgcgctgg ggcaggcgga agatatcgcc
    51961 attcgtatgc gtcagtacac cgacgaatat cttgataaca ttacaccgcc gttcacgaaa
    52021 gccttgttta cctacgttaa agagcggaag tacacctttt gtacgccggg gcatatgggc
    52081 ggcaccgcat atcaaaaaag cccggttggc tgcctgtttt atgatttttt cggcgggaat
    52141 accctcaagg ctgatgtctc tatttcggtc accgagcttg gttcgttgct cgaccacacc
    52201 gggccacact tggaagcgga agagtacatc gcgcggactt ttggcgcgga acagagttat
    52261 atcgttacca acggaacatc gacgtcgaac aaaattgtgg gtatgtacgc cgcgccatcc
    52321 ggcagtacgc tgttgatcga ccgcaattgt cataaatcgc tggcgcatct gttgatgatg
    52381 aacgatgtag tgccagtctg gctgaaaccg acgcgtaatg cgttggggat tcttggtggg
    52441 atcccgcgcc gtgaatttac tcgcgacagc atcgaagaga aagtcgctgc caccacgcag
    52501 gcacaatggc cggttcatgc ggtgattacc aactccacct atgatggctt gctctacaac
    52561 accgactgga tcaaacagac gctggatgtc ccgtcgatcc acttcgattc cgcctgggtg
    52621 ccgtacaccc attttcatcc gatctaccag gggaaaagtg gtatgagcgg cgagcgtgtt
    52681 gcgggaaaag tgatcttcga aacgcaatcg acccacaaaa tgctggcggc gttatcgcag
    52741 gcttcgctga tccacattaa aggcgagtat gacgaagagg cgtttaacga agcctttatg
    52801 atgcatacca ccacctcgcc cagttatccc attgttgctt cggttgagac ggcggcggcg
    52861 atgctgcgtg gtaatccggg caaacggctg attaaccgtt cggtggagcg ggcgctgcat
    52921 tttcgcaaag aggtccagcg gttgcgggaa gagtctgacg gttggttttt cgatatctgg
    52981 caaccgccgc aggtggatga agccgaatgc tggcccgttg cgccaggcga acagtggcac
    53041 ggctttaacg atgcggatgc cgatcatatg tttctcgatc cggttaaagt cactattttg
    53101 acaccgggga tggacgaaca gggcaatatg agtgaggagg ggatcccggc ggcgctggtg
    53161 gcaaaattcc tcgacgaacg tgggatcgta gtagagaaaa ccggccctta taacctgctg
    53221 tttctcttta gtattggtat cgataaaacc aaagcaatgg gattattgcg tgggttgacg
    53281 gaatttaaac gctcttacga tctcaacctg cggatcaaaa atatgctacc cgatctctat
    53341 gctgaagatc ccgatttcta ccgcaatatg cgtattcagg atctggcgca agggatccat
    53401 aagctgattc gtaaacacga tcttcccggt ttgatgttgc gggcattcga tactttgccg
    53461 gaaatgatca tgacgccaca tcaggcatgg cagagacaga ttaaaggtga agtagaaacc
    53521 attgcgctgg aacaactggt cggtagagta tcggcaaata tgatcctgcc ttatccaccg
    53581 ggcgtaccgc tgttgatgcc aggagaaatg ctgaccaaag agagccgcac ggtactcgat
    53641 tttctactga tgctttgttc cgtagggcaa cattaccccg gttttgaaac ggatattcac
    53701 ggcgcgaaac aggacgaaga cggcgtttac cgcgtacgag tcctaaaaat ggcgggataa
    53761 cttgccagag cggcttccgg gcgagtaacg tgctgttaac aaataaagga gacgttatgc
    53821 tgggtttaaa acaggttcac catattgcga ttattgcgac ggattatgcg gtgagcaaag
    53881 ctttctactg cgatattctt ggtttcacgc tgcaaagcga agtctatcgc gaagcgcgcg
    53941 actcgtggaa aggggatttg gcgcttaatg ggcaatatgt gattgagctt ttctcttttc
    54001 cgttcccgcc ggagcgcccc agccgaccgg aagcttgcgg cctgcgtcat ctggctttta
    54061 gcgttgatga catcgatgcg gcagtggcgc accttgaaag ccataacgtg aagtgtgaag
    54121 ccatccgtgt cgatccatac acgcaaaaac gcttcacctt ctttaacgat ccggacgggc
    54181 tgccgttgga actgtatgag cagtaaggct tgtcatcgcc gcatttgccc ggtaacgtgc
    54241 cgggcattgc tactgtaaaa tcgcaccatc atgacactca cgctcaatag acaacttctc
    54301 acctcacgcc agattctggt ggcctttagc ggcgggcttg actccaccgt tctgctgcat
    54361 cagttggtgc agtggcggac ggaaaatccg ggcgtcactc tgcgcgctat tcatgtgcat
    54421 cacggtttaa gtgccaatgc cgatgcctgg gttacgcatt gcgaaaacgt ctgccaacag
    54481 tggcaggtgc cgctggtggt cgaacgcgta caacttgcgc aagaggggct ggggattgag
    54541 gcccaagcgc ggcaggcgcg ttatcaggca tttgcccgta ccctattgcc cggcgaagtg
    54601 ctggtcaccg cgcaacatct cgacgatcaa tgtgaaacct ttctgctggc gctaaaacgc
    54661 ggtagcggcc ctgccgggct ttcggctatg ggggaagtct cggagtttgc cggaacacgg
    54721 cttatccgcc cgttgcttgc ccgcacgcgg ggggaactgg cgcagtgggc attggcgcat
    54781 ggtttacgct ggattgaaga cgaaagtaat caggacgact catacgatcg taactttctg
    54841 cgcctgcgtg tagtgccgtt attgcagcag cgttggccgc attttgccga agcaacggcc
    54901 cgcagcgccg cactttgtgc tgaacaagag agtctgttgg atgaactgct ggcggatgat
    54961 ttagcacact gccaaacgtc gcaggggacg ctgcagattg cgccaatgct agcgatgagt
    55021 gatgcccgtc gcgcggcgat tatccgccgc tggctggcag ggcagaatgc accgatgcct
    55081 tcccgcgacg cgctggtgcg gatctggcag gaagtggcgc tggcgcggga agatgcctcc
    55141 ccctgtttac gcttgggcgc gtttgaaatc cgccgatatc agtcgcaact gtggtggatt
    55201 aaatccgtca ccgggcaaag tgaaaccatt gtgccgtggc agacgtggct acaaccgctg
    55261 gaattaccgg cggggctggg aagcgtacag cttactgcgg gaggcgatat tcgccctccg
    55321 cgtgcagacg aagcggtcag cgtgcgtttc aaagcggcag gattgctgca tattgtcggg
    55381 cgcaacggcg gacgtaagct gaagaaaatc tggcaagagt taggcgtgcc gccgtggcta
    55441 cgtgacacca cgccactgct gttttatggc gaaacgctga ttgcggcggc aggggtattt
    55501 gtgacgcaag aaggtgtggc tgaaggtgag aatggcgtaa gttttgtctg gcagaaaacg
    55561 cttagttaag tgaaagccgg ataagacgca tcaaacgtcg catccggcga aagtcaatca
    55621 ggactcgctc accaccaccg taccgatttc cgggtggcta aagctggtaa ttttatccag
    55681 acgtagctca cgggtttcgc cagcggcctc gacgaccaga tactccacat ttttgcggga
    55741 gactaaatcg ctggcttttg cctgcaattt ttcgccatct ttcagctcaa gtgtcagcat
    55801 taaatgatgc tggcaggcga gctcaagatt atcgtaatca tcacaattga ttggttgata
    55861 cgtatcattc attgacataa tcgctcacca gtaagtttgc cgcagcgtat gctgcttttt
    55921 ccctgacagc ctcagaaagg gcgtcgtcgg cagccatttc attcagcact ttcaaaacgc
    55981 agcccagcgc gtccggaacg tatcctaagt ctccgctggc gatttccgcg taccgcttgc
    56041 gtattaactc acaatatttt tccacatgcc ctcctgtcag cactctgact taaccgtgga
    56101 tgcaagtcta agcctacgaa gataaactct gtttcgcaag gtgactatac cacactcatt
    56161 tctgcaatat cagcgccgca actgcacgta ttccgttaca atggcctcct gattcgaaag
    56221 gagttttctt atggcgctta aagcgacaat ttataaagcg acggttaatg tggccgatct
    56281 cgaccgcaac cagtttctcg atgcctctct gacgctggcg cgccaccctt cagaaaccca
    56341 ggagcgtatg atgctgcgct tgctggcgtg gctgaaatat gctgatgaac gtctgcaatt
    56401 tacccgtggt ttgtgtgccg atgatgagcc ggaagcgtgg ctgcgtaacg atcacctggg
    56461 cattgatttg tggattgagc tggggctgcc ggatgagcgg cggattaaga aagcctgcac
    56521 ccaggccgca gaagtggcgc tgtttaccta taatagtcgg gcggcgcaaa tctggtggca
    56581 gcaaaatcag agcaaatgtg tgcagtttgc caatctttcc gtctggtatc tggacgatga
    56641 acaactggcg aaagtaagcg cctttgccga tcgtaccatg acgctgcagg caacgattca
    56701 ggatggcgtg atctggttat cggacgataa gaataatctg gaagttaact taaccgcctg
    56761 gcaacaacct tcatgattgt gatttcccga catgttgcta ttcccgatgg tgagcttgag
    56821 atcaccgcca ttcgtgcgca gggcgcgggc gggcagcatg ttaataagac ctcaacggcc
    56881 attcatctgc gttttgacat tcgggcgtcc agcctgccag agtattacaa agagcgtcta
    56941 ctcgccgcca gccatcattt gatcagcagt gatggcgtga ttgtcattaa ggcacaggaa
    57001 taccgcagtc aggaactgaa ccgcgaagcc gcgctagccc ggctggtggc agtgattaaa
    57061 gatttaacaa cagaacaaaa agcccgacga cccacgcggc ccacccgtgc atcgaaagag
    57121 cgcaggctgg catcgaaagc acaaaaatca agcgtgaagg cgatgcgcgg caaagtacgc
    57181 agcggtcggg aataaaaaga aggaatagat ggtgaaaaaa gcgatagtga cagcgatggc
    57241 tgtaatcagc ctctttactc tgatgggatg taataaccgg gccgaagtcg atacgctttc
    57301 tccagcacag gctgccgaac tgaaaccgat gccgcaaagt tggcgcggcg tgctgccgtg
    57361 tgctgattgc gaaggaatcg aaacctctct gttcctcgaa aaagacggaa catgggtgat
    57421 gaatgagcgt tatctcggtg ctcgtgaaga accttcctcc ttcgcttcct acggtacatg
    57481 ggcgcgaacc gctgacaagc tggtattaac cgacagcaaa ggtgaaaagt catattatcg
    57541 ggcgaaaggc gatgcgctgg agatgctcga tcgtgaaggc aatccgattg aatcgcagtt
    57601 caactatacg ctggaaccgg cacaatctag tttacctatg acgccgatga ccctgcgagg
    57661 catgtatttt tatatggctg atgcggcgac cttcactgat tgcgcgaccg gaaaacgttt
    57721 catggtagcg aataacgcag agctggagcg tagctacctg gctgcgcgcg gtcacagtga
    57781 aaaaccggtg ttactgtcag tagaaggtca ctttacgctt gaggctaatc cggatactgg
    57841 tgcgccaacc aaagtattag cgcccgatac ggcgggtaaa ttttacccga ataaggattg
    57901 cagtagtttg gggcagtaaa cctgcttaag gcagaaacaa acgcaaaatt gcctgatgcg
    57961 ctgc
//
LOCUS       DAPGUL010000016        57433 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.016, whole genome shotgun sequence.
ACCESSION   DAPGUL010000016 DAPGUL010000000
VERSION     DAPGUL010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 57433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57433
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.016"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(134..3658)
                     /gene="nifJ"
                     /locus_tag="RHX21_001118"
     CDS             complement(134..3658)
                     /gene="nifJ"
                     /locus_tag="RHX21_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HDV1986342.1"
                     /translation="MITIDGNGAVASVAFRTSEVIAIYPITPSSTMAEQADAWAGNGL
                     KNVWGDTPRVVEMQSEAGAIATVHGALQTGALSTSFTSSQGLLLMIPTLYKLAGELTP
                     FVLHVAARTVATHALSIFGDHSDVMAVRQTGCAMLCAANVQEAQDFALISHIATLKSR
                     VPFIHFFDGFRTSHEINKIVPLADDTILDLMPQAEIDAHRARALNPEHPVIRGTSANP
                     DTYFQSREATNPWYDAVYDHVEQAMNDFSAATGRQYQPFEYYGHPQAERVIILMGSAI
                     GTCEEVVDELLTRGEKVGVLKVRLYRPFSAKHLLQALPGSVRSVAVLDRTKEPGAQAE
                     PLYLDVMTALAEAFNNGERETLPRVIGGRYGLSSKEFGPDCVLAVFSELNAAKPKARF
                     TVGIYDDVTNLSLPLPENTLPNSAKLEALFYGLGSDGSVSATKNNIKIIGNSTPWYAQ
                     GYFVYDSKKAGGLTVSHLRVSEQPIRSAYLISQADFVGCHQLQFIDKYQMAERLKPGG
                     IFLLNTPYSADEVWSRLPQEVQAVLNQKKARFYVINAAKIARECGLAARINTVMQMAF
                     FHLTQILPGDSALAELQGAIAKSYSSKGQDLVERNWQALALARESVEEVPLQPVNPHS
                     ANRPPVVSDAAPDFVKTVTAAMLAGLGDALPVSALPPDGTWPMGTTRWEKRNIAEEIP
                     IWKEELCTQCNHCVAACPHSAIRAKVVPPEAMENAPASLHSLDVKSRDMRGQKYVLQV
                     APEDCTGCNLCVEVCPAKDRQNPEIKAINMMSRLEHVEEEKINYDFFLNLPEIDRSKL
                     ERIDIRTSQLITPLFEYSGACSGCGETPYIKLLTQLYGDRMLIANATGCSSIYGGNLP
                     STPYTTDANGRGPAWANSLFEDNAEFGLGFRLTVDQHRVRVLRLLDQFADKIPAELLT
                     ALKSDATPEVRREQVAALRQQLNDVAEAHELLRDADALVEKSIWLIGGDGWAYDIGFG
                     GLDHVLGLTENVNILVLDTQCYSNTGGQASKATPLGAVTKFGEHGKRKARKDLGVSMM
                     MYGHVYVAQISLGAQLNQTVKAIQEAEAYPGPSLIIAYSPCEEHGYDLALSHDQMRQL
                     TATGFWPLYRFDPRRADEGKLPLALDSRPPSVALEETLLHEQRFRRLNSQQPEVAEQL
                     WKDAAADLQKRYDFLAQMAGKAEKSNTD"
     gene            3932..4198
                     /locus_tag="RHX21_001119"
     CDS             3932..4198
                     /locus_tag="RHX21_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015964583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing protein"
                     /protein_id="HDV1986343.1"
                     /translation="MRAAFWVGCAALLLSACSSEPVQQATAAHVAPGLKASMSSSGEA
                     NCAMIGGSLSVARQLDGTAIGMCALPNGKRCSEQSLAAGSCGSY"
     gene            complement(4195..4617)
                     /gene="hslJ"
                     /locus_tag="RHX21_001120"
     CDS             complement(4195..4617)
                     /gene="hslJ"
                     /locus_tag="RHX21_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein HslJ"
                     /protein_id="HDV1986344.1"
                     /translation="MKKVAALVALSLLMAGCVSNDKIAVTPEQLQHHRFVLESVNGKP
                     VTNDKNPPEISFGEKMMISGSMCNRFSGEGKLSNGELTAKGLAMTRMMCANPQLNELD
                     NTISEMLKEGAQVDLTANQLTLATAKQTLTYKLADLMN"
     gene            complement(4728..5717)
                     /gene="ldhA"
                     /locus_tag="RHX21_001121"
     CDS             complement(4728..5717)
                     /gene="ldhA"
                     /locus_tag="RHX21_001121"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HDV1986345.1"
                     /translation="MKLAVYSTKQYDKKYLQQVNESFGFELEFFDFLLTEKTAKTANG
                     CEAVCIFVNDDGSRPVLEELKKHGVKYIALRCAGFNNVDLDAAKELGLKVVRVPAYDP
                     EAVAEHAIGMMMTLNRRIHRAYQRTRDANFSLEGLTGFTMYGKTAGVIGTGKIGVAML
                     RILKGFGMRLLAFDPYPSAAALELGVEYVDLPTLFSESDVISLHCPLTPENYHLLNEA
                     AFDQMKNGVMIVNTSRGALIDSQAAIEALKNQKIGSLGMDVYENERDLFFEDKSNDVI
                     QDDVFRRLSACHNVLFTGHQAFLTAEALTSISQTTLQNLSNLEKGETCPNELV"
     gene            5925..8564
                     /locus_tag="RHX21_001122"
     CDS             5925..8564
                     /locus_tag="RHX21_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbH family protein"
                     /protein_id="HDV1986346.1"
                     /translation="MLGKYKAVLALLLLIILVPLTLLMTLGLWVPTLAGIWLPLGTRI
                     ALDESPRITRKGLIIPDLRYLVGDCQLAHITNASLSHPSRWLLYVGMVELDSACLAKL
                     PQTEQSPAAPKTLAQWQSMLPNTWINIDKLIFSPWQEWQGKLSLALTSDIQQLRYQGE
                     KVKFQGQLKGQQLTVSELDVVAFENQPPVKLVGEFTMPLVPDGLPVSGHATATLNLPQ
                     EPSLVDAELDWQENSGQLIVLARDNGDPLLDLPWQITRQQLTVSDGRWSWPYAGFPLS
                     GRLGVKVDNWQAGLENALISGRLSVLTQGQAGKGNAVLNFGPGKLSMDNSQLPLQLTG
                     EAKQADLILYARLPAQLSGSLSDPTLTFEPGALLRSKGRVIDSLDIDEIRWPLAGVKV
                     TQRGVDGRLQAILQAHENELGDFVLHMDGLANDFLPDAGRWQWRYWGKGSFTPMNATW
                     DVAGKGEWHDSTITLTDLSTGFDQLQYGTMTVEKPRLILDKPVVWVRDAQHPSFSGAL
                     SLDAGQTLFTGGSVLPPSTLKFSVDGRDPTYFLFKGDLHAGEIGPVRVNGRWDGIRLR
                     GNAWWPKQSLTVFQPLVPPDWKMNLRDGELYAQVAFSAAPEQGFRAGGHGVLKGGSAW
                     MPDNQVNGVDFVLPFRFADGAWHLGTRGPVTLRIAEVINLVTAKNITADLQGRYPWTE
                     EEPLLLTDVSVDVLGGNVLMKQLRMPQHDPALLRLNNLSSSELVSAVNPKQFAMSGAF
                     SGALPLWLNNEKWIVKDGWLANSGPMTLRLDKDTADAVVKDNMTAGSAINWLRYMEIS
                     RSSTKINLDNLGLLTMQANITGTSRVDGKSGTVNLNYYHEENIFTLWRSLRFGDNLQA
                     WLEQNARLPGNDCPQGKECEEKQ"
     gene            8561..8746
                     /locus_tag="RHX21_001123"
     CDS             8561..8746
                     /locus_tag="RHX21_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnbE family lipoprotein"
                     /protein_id="HDV1986347.1"
                     /translation="MKILLAALTSSFMLAACTPRIEVAAPKEPITINMNVKIEHEIII
                     KADKDVEELLETRSDLF"
     gene            8751..9080
                     /locus_tag="RHX21_001124"
     CDS             8751..9080
                     /locus_tag="RHX21_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707676.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbL family protein"
                     /protein_id="HDV1986348.1"
                     /translation="MMKKTLLLCAFLVGLVSSNVMALTLDEARTQGRVGETFYGYLVA
                     LKTDAETEKLVTDINAERKASYQQLAKQNNVSVDDIAKLAGQKLVARAKPGEYVQGIN
                     GKWVRKF"
     gene            complement(9252..10157)
                     /gene="feaR"
                     /locus_tag="RHX21_001125"
     CDS             complement(9252..10157)
                     /gene="feaR"
                     /locus_tag="RHX21_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator FeaR"
                     /protein_id="HDV1986349.1"
                     /translation="MNPAVDNEFQQWLSQINQVCGNFTGRLLTERYTGVLDTHFAKGL
                     KLSTVTTSGVNLSRTWQEVKGSDDAWFYTVFQLSGQAIMEQDERQVQIGAGDITLLDA
                     SRPCSLYWQESSKQISLLLPRTLLEQYFPHQKPVCAERLDADLPMVQLSHRLLQESMN
                     NPALSETESEAALQAMVCLLRPVLHQRESVQPRRERQFQKVVTLIDDNIREEILRPEW
                     IAGETGMSVRSLYRMFADKGLVVAQYIRNRRLDFCADAIRHAADDEKLAGIGFHWGFS
                     DQSHFSTVFKQRFGMTPGEYRRKFR"
     gene            10393..11892
                     /gene="feaB"
                     /locus_tag="RHX21_001126"
                     /gene_synonym="maoB"
                     /gene_synonym="padA"
     CDS             10393..11892
                     /gene="feaB"
                     /locus_tag="RHX21_001126"
                     /gene_synonym="maoB"
                     /gene_synonym="padA"
                     /EC_number="1.2.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415903.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetaldehyde dehydrogenase"
                     /protein_id="HDV1986350.1"
                     /translation="MTEPHVAVLSQVQQFLDRQHGLYIDGRPGPAQSEKRLAIFDPAT
                     GQEIASTADANEADVDNAVMSAWRAFVSRRWAGRLPAERERILLRFADLVEQHSEELA
                     QLETLEQGKSIAISRAFEVGCTLNWMRYTAGLTTKIAGKTLDLSIPLPQGARYQAWTR
                     KEPVGVVAGIVPWNFPLMIGMWKVMPALAAGCSIVIKPSETTPLTMLRVAELASEAGI
                     PDGVFNVVTGSGAVCGAALTSHPHVAKISFTGSTATGKGIARTAADHLTRVTLELGGK
                     NPAIVLKDADPQWVIEGLMTGSFLNQGQVCAASSRIYIEAPLFDTLVSGFEQAVKSLQ
                     VGPGMSPVAQINPLVSRAHCDKVCSFLDDAQAQQAELIRGSNGPAGEGYYVAPTLVVN
                     PDAKLRLTREEVFGPVVNLVRVADGEEALQLANDTEYGLTASVWTQNLSQALEYSDRL
                     QAGTVWVNSHTLIDANLPFGGMKQSGTGRDFGPDWLDGWCETKSVCVRY"
     gene            complement(11950..14223)
                     /gene="tynA"
                     /locus_tag="RHX21_001127"
     CDS             complement(11950..14223)
                     /gene="tynA"
                     /locus_tag="RHX21_001127"
                     /EC_number="1.4.3.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415904.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primary-amine oxidase"
                     /protein_id="HDV1986351.1"
                     /translation="MGSPSLYSARKTALALAVALSFAWQAPVFAHGGEAHMVPMDKTL
                     KEFGADVQWDDYAQIFTLIKDGAYVKVKPGAQTAIVNGQSLALQVPVVMKDNKAWVSD
                     TFINDVFQSGLDQTFQVEKRPHPLNALTADEIKQAVEIVKASADFKPNTRFTEISLLP
                     PDKEAVWAFALENKPVDQPRKADVIMLDGKHIIEAVVDLQNNKLLSWQPIKDAHGMVL
                     LDDFASVQNIINNSEEFAAAVKKRGITDAKKVITTPLTVGYFDGKDGLKQDARLLKVI
                     SYLDVGDGNYWAHPIENLVAVVDLEQKKIVKIEEGAVVPVPMTARPFDGRDRVAPAVK
                     PMQIIEPEGKNYTITGDMIHWRNWDFHLSMNSRVGPMISTVTYNDNGTKRKVMYEGSL
                     GGMIVPYGDPDIGWYFKAYLDSGDYGMGTLTSPIARGKDAPSNAVLLNETIADYTGVP
                     MEIPRAIAVFERYAGPEYKHQEMGQPNVSTERRELVVRWISTVGNYDYIFDWIFHENG
                     TIGIDAGATGIEAVKGVKAKTMHDETAKDDTRYGTLIDHNIVGTTHQHIYNFRLDLDV
                     DGENNSLVAMDPVVKPNTAGGPRTSTMQVNQYNIGNEQDAAQKFDPGTIRLLSNPNKE
                     NRMGNPVSYQIIPYAGGTHPVAKGAQFAPDEWIYHRLSFMDKQLWVTRYHPGERFPEG
                     KYPNRSTHDTGLGQYSKDNESLDNTDAVVWMTTGTTHVARAEEWPIMPTEWVHTLLKP
                     WNFFDETPTLGALKKDK"
     gene            complement(14471..16516)
                     /gene="paaZ"
                     /locus_tag="RHX21_001128"
     CDS             complement(14471..16516)
                     /gene="paaZ"
                     /locus_tag="RHX21_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation bifunctional
                     protein PaaZ"
                     /protein_id="HDV1986352.1"
                     /translation="MQQLASFLSGTWQSGRGRSRLIHHAISGEALWEVTSEGLDMAAA
                     RQFAIEKGAPALRAMTFIERAAMLKAVAKHLLSEKERFYALSAQTGATRADSWVDIEG
                     GIGTLFTYASLGSRELPDDTLWPEDELIPLSKEGGFAARHVLTSKSGVAVHINAFNFP
                     CWGMLEKLAPTWLGGMPAIIKPATATAQLTQAMVKSIVDSGLVPEGAISLICGSAGDL
                     LDHLDSQDVVTFTGSAATGQMLRVQPNIVAKSIPFTMEADSLNCCVLGEDVTPDQPEF
                     ALFIREVVREMTTKAGQKCTAIRRIIVPQALVNAVSDVLVARLQKVVVGDPAQEGVKM
                     GALVNAEQRADVQEKVNILLAAGCEIRLGGQADLSAAGAFFPPTLLYCPQPDETPAVH
                     ATEAFGPVATLMPAQNQRHALQLACAGGGSLAGTLVTADPQIARQFITDAARTHGRIQ
                     ILNEESAKESTGHGSPLPQLLHGGPGRAGGGEELGGLRAVKHYMQRTAVQGSPTMLAA
                     ISKQWVRGAKVEEDRIHPFRKYFEELQPGDSLLTPRRTMTEADIVNFACLSGDHFYAH
                     MDKIAAAESIFGERVVHGYFVLSAAAGLFVDAGVGPVIANYGLENLRFIEPVKPGDTI
                     QVRLTCKRKTLKKQRSAEEKPTGVVEWAVEVFNQHQTPVALYSILTLVARQHGDFVD"
     gene            16801..17730
                     /gene="paaA"
                     /locus_tag="RHX21_001129"
     CDS             16801..17730
                     /gene="paaA"
                     /locus_tag="RHX21_001129"
                     /EC_number="1.14.13.149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,2-phenylacetyl-CoA epoxidase subunit A"
                     /protein_id="HDV1986353.1"
                     /translation="MTQEERFEQRIAQETAIEPQDWMPDAYRKTLIRQIGQHAHSEIV
                     GMLPEGNWITRAPTLRRKAILLAKVQDEAGHGLYLYSAAETLGCAREDIYQKMLDGRM
                     KYSSIFNYPTLSWADIGVIGWLVDGAAIVNQVALCRTSYGPYARAMVKICKEESFHQR
                     QGFEACMALAQGSEAQKQMLQDAINRFWWPALMMFGPNDDNSPNSARSLAWKIKRFTN
                     DELRQRFVDNTVPQVEMLGMTVPDPDLHFDTESGHYRFGEIDWQEFNEVINGRGICNQ
                     ERLDAKRKAWEEGTWVREAALAHAQKQLARKVA"
     gene            17742..18029
                     /gene="paaB"
                     /locus_tag="RHX21_001130"
     CDS             17742..18029
                     /gene="paaB"
                     /locus_tag="RHX21_001130"
                     /EC_number="1.14.13.149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,2-phenylacetyl-CoA epoxidase subunit B"
                     /protein_id="HDV1986354.1"
                     /translation="MSNVYWPLYEVFVRGKQGLSHRHVGSLHAADERMALENARDAYT
                     RRSEGCSIWVVKASEIVASQPEERGEFFDPAESKVYRHPTFYTIPDGIEHM"
     gene            18038..18784
                     /gene="paaC"
                     /locus_tag="RHX21_001131"
     CDS             18038..18784
                     /gene="paaC"
                     /locus_tag="RHX21_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate-CoA oxygenase subunit PaaC"
                     /protein_id="HDV1986355.1"
                     /translation="MNQLTAYTLRLGDNCLVLSQRLGEWCGHAPELEIDLALANIGLD
                     LLGQARNFLSYAAELAGEGDEDTLAFTRDERQFSNLLLVEQPNGNFADTIARQYFIDA
                     WHVALFTRLMESRDPQLAAISAKAIKEARYHLRFSRGWLERLGNGTDVSGQKMQQAIN
                     KLWRFTAELFDADEIDIALSEEGIAVDPRTLRAAWEAEVFAGINEATLNVPQEQAYRT
                     GGKKGLHTEHLGPMLAEMQYLQRVLPGQQW"
     gene            18799..19296
                     /gene="paaD"
                     /locus_tag="RHX21_001132"
     CDS             18799..19296
                     /gene="paaD"
                     /locus_tag="RHX21_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415909.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate degradation protein PaaD"
                     /protein_id="HDV1986356.1"
                     /translation="MQRLATIAPPQVHEIWALLSQIPDPEIPVLTITDLGMVRNVTQM
                     GEGWVIGFTPTYSGCPATEHLIGAIREAMTTHGFTPVQVVLQLDPAWTTDWMTPDARE
                     RLRQYGISPPAGHSCHAHLPPEVRCPRCASVHTTLISEFGSTACKALYRCDSCREPFD
                     YFKCI"
     gene            19304..20374
                     /gene="paaK"
                     /locus_tag="RHX21_001133"
     CDS             19304..20374
                     /gene="paaK"
                     /locus_tag="RHX21_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate-CoA oxygenase/reductase subunit
                     PaaK"
                     /protein_id="HDV1986357.1"
                     /translation="MTTFHSLTVAKVEPETRDAVTITFAVPQPLQEAYRFRPGQHLTL
                     KASFDGEELRRCYSICRSYLPGEISVAVKAIEGGRFSRYAREHIRQGMTLEVMVPQGH
                     FGYQPQAERQGRYLAIAAGSGITPMLAIIATTLQTEPESQFTLIYGNRTSQSMMFRQA
                     LADLKDKYPQRLQLLCIFSQETLDSDLLHGRIDGEKLQSLGASLINFRLYDEAFICGP
                     AAMMDETEAALKALGMPDKTIHLERFNTPGTRVKRSVNVQSDGQKVTVRQDGRDREIV
                     LNADDESILDAALRQGADLPYACKGGVCATCKCKVLRGKVAMETNYSLEPDELAAGYV
                     LSCQALPLTSDVVVDFDAKGMA"
     gene            20371..21138
                     /locus_tag="RHX21_001134"
     CDS             20371..21138
                     /locus_tag="RHX21_001134"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-dehydroadipyl-CoA hydratase"
                     /protein_id="HDV1986358.1"
                     /translation="MSELIVSRQQQVLLLTLNRPAARNALNNALLTQLVNELEAAATD
                     SSISVCVITGNARFFAAGADLNEMAEKDLAATLNDTRPQLWARLQAFNKPLIAAVNGY
                     ALGAGCELALLCDVVVAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASKMVLSG
                     ESITAQQAQQAGLVSDVFPSDLTLEYALQLASKMARHSPLALQAAKQALRQSQEVALQ
                     AGLAQERQLFTLLAATEDRHEGISAFLQKRTPDFKGR"
     gene            21138..21926
                     /gene="paaB"
                     /locus_tag="RHX21_001135"
     CDS             21138..21926
                     /gene="paaB"
                     /locus_tag="RHX21_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA
                     isomerase"
                     /protein_id="HDV1986359.1"
                     /translation="MMEFILSHVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVER
                     DDTIRCLLLTGAGRGFCAGQDLNDRNVDPTGPAPDLGMSVERFYNPLVRRLAKLPKPV
                     ICAVNGVAAGAGATLALGCDIVIAARSAKFVMAFSKLGLVPDCGGTWLLPRVAGRARA
                     MGLALLGNQLSAEQAHEWGMIWQVVDDETLADTAQQLARHLATQPTFGLGLIKQAINS
                     AETNTLDTQLDLERDYQRLAGRSADYREGVSAFLAKRSPQFTGK"
     gene            21928..23355
                     /gene="paaC"
                     /locus_tag="RHX21_001136"
     CDS             21928..23355
                     /gene="paaC"
                     /locus_tag="RHX21_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-CoA dehydrogenase PaaC"
                     /protein_id="HDV1986360.1"
                     /translation="MMINVQTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRA
                     IDGIHARLNSRVTRGKLTAETCERTLKRLIPVTDIHALAAANLVIEAASERLEVKKAL
                     FAQLAEVCPPQTLLTTNTSSISITAIAAEVKNPERVAGLHFFNPAPVMKLVEVVSGLA
                     TAAEVVEQLCELTLSWGKQPVRCHSTPGFIVNRVARPYYSEAWRALEEQVAAPEVIDA
                     ALRDGAGFPMGPLELTDLIGQDVNFAVTCSVFNAFWQERRFLPSLVQQELVIGGRLGK
                     KSGLGVYDWRAEREAVVGLEAVSDSFSPMKVEKKSDGVTEIDDVLLIETQGETAQALA
                     IRLARPVVVVDKMAGKVVTIAAAAVNPDSATRKAIYYLQQQGKTVLQIADYPGMLIWR
                     TVAMIINEALDALQKGVASEQDIDTAMRLGVNYPYGPLAWGAQLGWQRILRLLENLQH
                     HYGEERYRPCSLLRQRALLESGYES"
     gene            23345..23767
                     /gene="paaI"
                     /locus_tag="RHX21_001137"
     CDS             23345..23767
                     /gene="paaI"
                     /locus_tag="RHX21_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyphenylacetyl-CoA thioesterase PaaI"
                     /protein_id="HDV1986361.1"
                     /translation="MSHKAWQNAHAMYENDACAKALGIDIISMDEGFAVVTMTVTAQM
                     LNGHQSCHGGQLFSLADTAFAYACNSQGLAAVASACTIDFLRPGFAGDTLTATAQVRH
                     QGKQTGVYDIEIVNQQQKTVALFRGKSHRIGGTITGEA"
     gene            23767..24972
                     /gene="paaJ"
                     /locus_tag="RHX21_001138"
                     /gene_synonym="paaE"
                     /gene_synonym="ydbW"
     CDS             23767..24972
                     /gene="paaJ"
                     /locus_tag="RHX21_001138"
                     /gene_synonym="paaE"
                     /gene_synonym="ydbW"
                     /EC_number="2.3.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase"
                     /protein_id="HDV1986362.1"
                     /translation="MREAFICDGIRTPIGRYGGALSGVRADDLAAIPLRELLVRNPRL
                     DAECIDDVILGCANQAGEDNRNVARMATLLAGLPQSVSGTTINRLCGSGLDALGFAAR
                     AIKAGDGDLLIAGGVESMSRAPFVMGKATSAFSRQAEMFDTTIGWRFVNPLMAQQFGT
                     DSMPETAENVAELLKISREDQDSFALRSQQRTAKAQSSGILAEEIVPVVLKNKKGVVT
                     EIQHDEHLRPETTLEQLRGLKAPFRANGVITAGNASGVNDGAAALIIASEQMAAAQGL
                     TPRARIVAMATAGVEPRLMGLGPVPATRRVLERAGLSIHDMDVIELNEAFAAQALGVL
                     RELGLPDDAPHVNPNGGAIALGHPLGMSGARLALAASHELHRRNGRYALCTMCIGVGQ
                     GIAMILERV"
     gene            24999..26312
                     /gene="paaF"
                     /locus_tag="RHX21_001139"
     CDS             24999..26312
                     /gene="paaF"
                     /locus_tag="RHX21_001139"
                     /EC_number="6.2.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetate--CoA ligase"
                     /protein_id="HDV1986363.1"
                     /translation="MITNTKLDPIETASVDELQALQTQRLKWTLKHAYENVPMYRRKF
                     DAAGVHPDDFRELSDLRKFPCTTKQDLRDNYPFDTFAVPMEQVVRIHASSGTTGKPTV
                     VGYTQNDIDNWANIVARSLRAAGGTPKDKIHVAYGYGLFTGGLGAHYGAERLGATVIP
                     MSGGQTEKQAQLIRDFQPDMIMVTPSYCLNLIEELERQLGGDASGCSLRVGVFGAEPW
                     TQAMRKEIERRLGITALDIYGLSEVMGPGVAMECLETTDGPTIWEDHFYPEIVNPHDG
                     TPLADGEHGELLFTTLTKEALPVIRYRTRDLTRLLPGTARTMRRMDRISGRSDDMLII
                     RGVNVFPSQLEEEIVKFEHLSPHYQLEVNRRGHLDSLSVKVELKESSLTLTHEQRCQV
                     CHQLRHRIKSMVGISTDVMIVNCGSIPRSEGKACRVFDLRNIVGA"
     gene            26413..27363
                     /gene="paaX"
                     /locus_tag="RHX21_001140"
     CDS             26413..27363
                     /gene="paaX"
                     /locus_tag="RHX21_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation operon negative
                     regulatory protein PaaX"
                     /protein_id="HDV1986364.1"
                     /translation="MSKLDTFIQHAVNAVPVSGTSLISSLYGDSLSHRGGEIWLGSLA
                     ALLEGLGFGERFVRTALFRLNKEGWLDVSRIGRRSFYSLSDKGLRLTRRAESKIYRAE
                     QPAWDGKWLLLLSEGLDKSTLADVKKQLIWQGFGALAPSLMASPSQKLADVQTLLHEA
                     GVADNVICFEAQIPLALSRAALRARVEECWHLTEQNAMYETFIQSFRPLVPLLKEAAD
                     ELTPERAFHIQLLLIHFYRRVVLKDPLLPEELLPAHWAGHTARQLCINIYQRVAPAAL
                     AFVSEKGETSVGELPAPGSLYFQRFGGLNIEQEAICQFTR"
     gene            27345..27935
                     /gene="paaY"
                     /locus_tag="RHX21_001141"
     CDS             27345..27935
                     /gene="paaY"
                     /locus_tag="RHX21_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation protein PaaY"
                     /protein_id="HDV1986365.1"
                     /translation="MPIYQIDGLTPVVPEESFVHPTAVLIGDVILGKGVYVGPNASLR
                     GDFGRIVVKDGANIQDNCVMHGFPEQDTVVEEDGHIGHSAILHGCIIRRNALVGMNAV
                     VMDGAVIGENSIVGASAFVKAKAEMPANYLIVGSPAKAIRELSEQELAWKKQGTHEYQ
                     VLVTRCKQTLHQVEPLREVEPNRKRLVFDENLRPKQ"
     gene            28166..29026
                     /gene="pdxI"
                     /locus_tag="RHX21_001142"
     CDS             28166..29026
                     /gene="pdxI"
                     /locus_tag="RHX21_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 4-dehydrogenase"
                     /protein_id="HDV1986366.1"
                     /translation="MSSNTFTLGTKSVNRLGYGAMQLAGPGVFGPPRDRHVAITVLRE
                     ALALGVNHIDTSDFYGPHVTNQIIREALYPYSDDLTIVTKIGARRGEDASWLPAFSPA
                     ELQKAVHDNLRNLGLDVLDVVNLRVMMGDGHGPAEGSIEASLTVLAEMQQQGLVKHIG
                     LSNVTPTQVAEARKIAEIVCVQNEYNIAHRADDAMIDALAHDGIAYVPFFPLGGFTPL
                     QSSTLSDVAASLGATPMQVALAWLLQRSPNILLIPGTSSVAHLRENMAAEKLHLSEEV
                     LSTLDGISRE"
     gene            29090..31395
                     /locus_tag="RHX21_001143"
                     /pseudo
     CDS             29090..31395
                     /locus_tag="RHX21_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415925.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2773 domain-containing bactofilin"
     gene            31566..32171
                     /locus_tag="RHX21_001144"
     CDS             31566..32171
                     /locus_tag="RHX21_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310037.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HDV1986367.1"
                     /translation="MTLYQIKPLFQSLLRPTMFWLYKHHVTANHITLAALALSLLTGL
                     LLVLVAQPILFLLLPIVLFIRMALNALDGMLARECNQQTRLGAILNETGDVISDIALY
                     LPFLFLPESNALLVILMLFCTILTEFCGLLAQTINGIRSYAGPFGKSDRALIFGLWGL
                     AVSIYPQWMQWNNLLWSIASILLLWTAINRCRSVLFMSAER"
     gene            32171..33067
                     /locus_tag="RHX21_001145"
     CDS             32171..33067
                     /locus_tag="RHX21_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HDV1986368.1"
                     /translation="MLEKSLATLFALLILATLINRFLLWRLPERKGGEVTLRIRTWWG
                     IVICFSLVISGPRWMTLTFFALISFLALKEYCTLISIHFPRWLYWVIPLNYLLIGFNC
                     FEMFLLFIPLSGFLISATWRVFVGEPSGFLHTVSAIFWGWIMTVFALSHAAWLLMFPS
                     MNIQGGALLVLFLLALTESNDIAQYLWGKSCGRRKVVPKVSPGKTLEGLVGGVITTMI
                     ASLIIGPLLTPLNTLQALLAGLLIGISGFCGDVVMSAIKRDIGVKDSGKLLPGHGGLL
                     DRIDSLIFTAPVFFYFIRYSCY"
     gene            33083..34840
                     /locus_tag="RHX21_001146"
     CDS             33083..34840
                     /locus_tag="RHX21_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional alpha/beta hydrolase/class I
                     SAM-dependent methyltransferase"
                     /protein_id="HDV1986369.1"
                     /translation="MENSRIPGEHFFTTSDNTALFYRHWPALQPGAKKVIVLFHRGHE
                     HSGRLQHLVDELAMPDTAFYAWDARGHGKTSGPRGYSPSLARSVQDVDEFVRFAASDS
                     QVGLEEVVVIAQSVGAVLVATWVHDYAPAIRGLVLASPAFKVKLYVPLARPALALWHR
                     LRGLFFINSYVKGRYLTHDRQRVASFNNDPLITRAIAVNILLDLYKTSERIVSDAAAI
                     TLPTQLLISGDDYVVHRQPQIDFYQRLRSPLKELHLLPGFYHDTLGEENRALAFEKMQ
                     SFISHLYANKSQKFDYQHEDCTGPSADRWRLLSGGPVPLSPVDLAYRFMRMAMKLFGA
                     HSAGLHLGMSTGFDSGSSLDYVYQNQPQGSNAFGRLVDKIYLNSVGWRGIRQRKTHLQ
                     MLIKQAVADLHAKGLAIRVVDIAAGHGRYVLDALENEPAVCDILLRDYSELNVAQGQE
                     MIAQRGMSGQVRFEQGDAFNPEELSALTPRPTLAIVSGLYELFPENEQVKNSLAGLAN
                     AIEPGGILIYTGQPWHPQLELIAGVLTSHKDGKPWVMRVRSQGEMDSLVRDAGFDKCT
                     QRIDEWGIFTVSMAVRRDN"
     gene            34830..36146
                     /locus_tag="RHX21_001147"
     CDS             34830..36146
                     /locus_tag="RHX21_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310040.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2/dual specificity phosphatase
                     family protein"
                     /protein_id="HDV1986370.1"
                     /translation="MITERRNVLLQGAGWLLLLAPFFFFTYGSLNQFTAVQDLNSHDI
                     PSQVFGWETAIPFLPWTIVPYWSLDLLYGFSLFVCSTTFEQRRLVHRLILATVMACCG
                     FLLYPLKFSFIRPEVSGVTGWLFSQLELFDLPYNQSPSLHIILCWLLWRHFRQHLAER
                     WRKVCGGWFLLIAISTLTTWQHHFIDVITGLAVGMLIDWMVPVDRRWNYQKPDQRRIK
                     IALPYVVGAGSCIVLMELMVMIQLWWSVWLCWPVLSLLIIGRGYGGLGAITTGKDSQG
                     KLPPAVYWLTLPCRIGMWLSMRWFCRRLEPVSKMTAGVYLGAFPRHIPAQNAVLDVTF
                     EFPRGRATKDRLYFCVPMLDLVVPEEGELRQAVAMLETLREEQGSVLVHCALGLSRSA
                     LVVAAWLLCYGHCKTVDEAISYIRARRSHIVLKEDHKAMLKLWENR"
     gene            complement(36197..36802)
                     /gene="azoR"
                     /locus_tag="RHX21_001148"
     CDS             complement(36197..36802)
                     /gene="azoR"
                     /locus_tag="RHX21_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HDV1986371.1"
                     /translation="MSKVLVLKSSILAGYSQSNQLSDYFVEQWREKHSADEITVRDLA
                     ANPIPVLDGELVGALRPSDAPLTPRQQEALALSDELIAELKAHDVIVIAAPMYNFNIS
                     TQLKNYFDLVARAGVTFRYTENGPEGLVTGKKAIVITSRGGIHKDGPTDLVTPYLSTF
                     LGFIGITDVKFVFAEGIAYGPEMAAKAQSDAKAAIDSIVAA"
     gene            37003..40905
                     /gene="hrpA"
                     /locus_tag="RHX21_001149"
     CDS             37003..40905
                     /gene="hrpA"
                     /locus_tag="RHX21_001149"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase HrpA"
                     /protein_id="HDV1986372.1"
                     /translation="MTEQQKLTFTALQQRLDSLMPRDRLRFSRRLHGVKKVKNPDAQQ
                     AIFQEMAKEIDQAAGKVLLREAARPEITYPDNLPVSQKKQDILEAIRDHQVVIVAGET
                     GSGKTTQLPKICMELGRGVKGLIGHTQPRRLAARTVANRIAEELKTEPGGCIGYKVRF
                     SDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLKELLP
                     RRPDLKIIITSATIDPERFSRHFNNAPIIEVSGRTYPVEVRYRPIVEEADDTERDQLQ
                     AIFDAVDELSQESPGDILIFMSGEREIRDTADALNKLNLRHTEILPLYARLSNSEQNR
                     VFQSHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQAS
                     ANQRKGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAA
                     FPFVEAPDKRNIQDGVRLLEELGAITTDEQASAYKLTPLGRQLSQLPVDPRLARMVLE
                     AQKHGCVREAMIITSALSIQDPRERPMDKQQASDEKHRRFHDKESDFLAFVNLWNYLG
                     EQQKALSSNAFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIHI
                     ALLTGLLSHIGMKDADKQEYTGARNARFSIFPGSGLFKKPPKWVMVAELVETSRLWGR
                     IAARIDPEWVEPVAQHLIKRTYSEPHWERAQGAVMATEKVTVYGLPIVAARKVNYSQI
                     DPALCRELFIRHALVEGDWQTRHAFFRENLKLRAEVEELEHKSRRRDILVDDETLFEF
                     YDQRISHDVISARHFDSWWKKVSRETPDLLNFEKSMLIKEGAEKISKLDYPNFWHQGN
                     LKLRLSYQFEPGADADGVTVHIPLPLLNQVEESGFEWQIPGLRRELVIALIKSLPKPV
                     RRNFVPAPNYAEAFLGRVTPLELPLLDSLERELRRMTGVTVDREDWHWDQVPDHLKIT
                     FRVVDDKNKKLKEGRSLQDLKDALKGKVQETLSAVADDGIEQSGLHIWSFGQLPESYE
                     QKRGNYKVKAWPALVDERDSVAIKLFDNPLEQKQAMWNGLRRLLLLNIPSPIKYLHEK
                     LPNKAKLGLYFNPYGKVLELIDDCISCGVDQLIDANGGPVWTEEGFAALHEKVRAELN
                     DTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALGLSDIKAQMGGLVYRGFVTGNGFK
                     RLGDTLRYLQAIEKRLEKLAVDPHRDRAQMLKVENVQQAWQQWINKLPPARREDEDVK
                     EIRWMIEELRVSYFAQQLGTPYPISDKRILQAMEQISG"
     gene            41177..41977
                     /locus_tag="RHX21_001150"
     CDS             41177..41977
                     /locus_tag="RHX21_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDV1986373.1"
                     /translation="MNITPFPTLSPATIDAINVIGQWLAQDDFSGEVPYQADCVILAG
                     NAVMPTIDAACKIARDQQIPLLISGGIGHSTTFLYSAIAQHPHYNTIRTTGRAEATIL
                     ADIAHQFWHIPHEKIWIEDQSTNCGENARFSIALLKQAVERVHTAIVVQDPTMQRRTM
                     ATFRRMTGDNPDAPRWLSYPGFVPQLGNNADSVIFINQLQGLWPVERYLSLLTGELPR
                     LRDDSDGYGPRGRDFIVHVDFPAEVIHAWQTLKHDAVLIEAMESRSLR"
     gene            42174..43613
                     /gene="aldA"
                     /locus_tag="RHX21_001151"
     CDS             42174..43613
                     /gene="aldA"
                     /locus_tag="RHX21_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HDV1986374.1"
                     /translation="MSVPVQHPMYIDGQFVTWRGDAWIDVVNPATEAVISRIPDGQAE
                     DARKAIDAAERAQPEWEALPAIERASWLRKISAGIRERASEISALIVEEGGKIQQLAE
                     VEVAFTADYIDYMAEWARRYEGEIIQSDRPGENILLFKRALGVTTGILPWNFPFFLIA
                     RKMAPALLTGNTIVIKPSEFTPTNAIAFAKIVDEIGLPRGVFNLVLGRGETVGQELAG
                     NPKVAMVSMTGSVSAGEKIMATAAKNITKVCLELGGKAPAIVMDDADLELAVKAIVDS
                     RVINSGQVCNCAERIYVQKGIYDQFVNRLGEAMQAVQFGNPAERNDIAMGPLINAAAL
                     ERVEQKVARAVEEGARVALGGKAVEGKGYYYPPTLLLDVRQEMSIMHEETFGPVLPVV
                     AFDTLEEAISMANDSDYGLTSSIYTQNLNVAMKAIKGLKFGETYINRENFEAMQGFHA
                     GWRKSGIGGADGKHGLHEYLQTQVVYLQS"
     gene            complement(43655..44656)
                     /gene="gap"
                     /locus_tag="RHX21_001152"
     CDS             complement(43655..44656)
                     /gene="gap"
                     /locus_tag="RHX21_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDV1986375.1"
                     /translation="MSKVGINGFGRIGRLVLRRLLEVKSNIDVVAINDLTSPKILAYL
                     LKHDSNYGPFPWSVDFTEDSLIVDGKSIAVYAEKEAKNIPWKAKGAEIIVECTGFYTS
                     AEKSQAHLDAGAKKVLISAPAGEMKTIVYNVNDDTLDGNDTIVSVASCTTNCLAPMAK
                     ALHDSFGIEVGTMTTIHAYTGTQSLVDGPRGKDLRASRAAAENIIPHTTGAAKAIGLV
                     IPELSGKLKGHAQRVPVKTGSVTELVSILGKKVTAEEVNNALKQATTNNESFGYTDEE
                     IVSSDIIGSHFGSVFDATQTEITAVGDLQLVKTVAWYDNEYGFVTQLIRTLEKFAKL"
     gene            44845..45375
                     /gene="cybB"
                     /locus_tag="RHX21_001153"
     CDS             44845..45375
                     /gene="cybB"
                     /locus_tag="RHX21_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415935.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b561"
                     /protein_id="HDV1986376.1"
                     /translation="MENKYSRLQISIHWLVFLLVIAAYCAMEFRGFFPRSDRPLINMV
                     HVSCGISILVLMVVRLLLRLKYPTPPIIPKPKPMMTGLAHLGHLVIYLLFIALPVIGL
                     VMMYNRGNPWFAFGLTMPYASEANFERVDSLKSWHETLANLGYFVIGLHAAAALAHHY
                     FWKDNTLLRMMPRKRS"
     gene            45620..45793
                     /locus_tag="RHX21_001154"
     CDS             45620..45793
                     /locus_tag="RHX21_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986377.1"
                     /translation="MKKLALILFMGTLVSFYADAGRKPCSGSKGGISHCTAGGKFVCN
                     DGSISASKKTCTN"
     gene            complement(45865..46014)
                     /gene="hokB"
                     /locus_tag="RHX21_001155"
     CDS             complement(45865..46014)
                     /gene="hokB"
                     /locus_tag="RHX21_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokB"
                     /protein_id="HDV1986378.1"
                     /translation="MKHNPLVVCLLIICITILTFTLLTRQTLYELRFRDGDKEVAALM
                     ACTSR"
     gene            46413..48053
                     /gene="trg"
                     /locus_tag="RHX21_001156"
     CDS             46413..48053
                     /gene="trg"
                     /locus_tag="RHX21_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein Trg"
                     /protein_id="HDV1986379.1"
                     /translation="MNTTPSQRLGFLHHIRLVPLFACILGGILVLFALSSALAGYFLW
                     QADRDQRDVTAEIEIRTGLANSSDFLRSARINMIQAGAASRIAEMEAMKRNIAQAESE
                     IKQSQQGYRAYQNRPVKTPADEALDTELNQRFQAYITGMQPMLKYAKNGMFEAIINHE
                     SEQIRPLDNAYTDILNKAVKIRSTRANQLAELAHQRTRLGGMFMIGAFVLALVMTLIT
                     FMVIRRIVIRPLQHAAQRIEKIASGDLTMNDEPAGRNEIGRLNRHLQQMQHSLGMTVG
                     TVRQGAEEIYRGTSEISAGNADLSSRTEEQAAAIEQTAASMEQLTATVKQNADNAHHA
                     SKLAQEASIKASDGGQTVSGVVKTMGAISTSSKKISEITAVINSIAFQTNILALNAAV
                     EAARAGEQGRGFAVVASEVRTLASRSAQAAKEIEGLISESVRLIDLGSDEVATAGKTM
                     STIVDAVASVTHIMQEIAAASDEQSRGITQVSQAISEMDKVTQQNASLVEEASAAAVS
                     LEEQAARLTEAVDVFRLHKHSVSAEPRGAGEPVSFATV"
     gene            complement(48091..49014)
                     /locus_tag="RHX21_001157"
     CDS             complement(48091..49014)
                     /locus_tag="RHX21_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310054.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV1986380.1"
                     /translation="MEKNSLFSQRIRLRHLHTFVAVAQQGTLGRAAETLNLSQPALSK
                     TLNELEQLTGARLFERGRQGAQLTLPGEQFLTHAVRVLDAINTAGQSLHRKEGLNNDV
                     VRVGALPTAALGILPSVIGQFHQQQKETTLQVATMSNPMILAGLKTGEIDIGIGRMSD
                     PELMTGLNYELLFLESLKLVVRPNHPLLQENVTLSRVLEWPVVVSPEGTAPRQHSDAL
                     VQSQGCKIPSGCIETLSASLSRQLTVEYDYVWFVPSGAVKDDLRHATLVALPVPGHGA
                     GEPIGILTRVDATFSSGCQLMINAIRKSMPF"
     gene            49231..50574
                     /locus_tag="RHX21_001158"
     CDS             49231..50574
                     /locus_tag="RHX21_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDV1986381.1"
                     /translation="MANSITADEIREQFSQAMSAMYQQEVPQYGTLLELVADVNLAVL
                     ENNPQLHEKMVNADELARLNVERHGAIRVGTAQELATLRRMFAIMGMYPVSYYDLSQA
                     GVPVHSTAFRPIDDASLARNPFRVFTSLLRLELIENEILRQKAAEILRQRDIFTPRCR
                     QLLEEYEQQGGFNETQAQEFVQEALETFRWHQSATVDEETYRALHNEHRLIADVVCFP
                     GCHINHLTPRTLDIDRVQSMMPECGIEPKILIEGPPRREVPILLRQTSFKALEETVLF
                     AGQKQGTHTARFGEIEQRGVALTPKGRQLYDDLLRNAGTGQDNLTHQMHLQETFRTFP
                     DSEFLMRQQGLAWFRYRLTPSGEAHRQAIHPGDDPQPLIERGWVAAQPITYEDFLPVS
                     AAGIFQSNLGNETQTRSHGNASREAFEQALGCPVLDEFQLYQEAEERSKRRCGLL"
     gene            50799..52454
                     /gene="opgD"
                     /locus_tag="RHX21_001159"
                     /gene_synonym="mdoD"
     CDS             50799..52454
                     /gene="opgD"
                     /locus_tag="RHX21_001159"
                     /gene_synonym="mdoD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucan biosynthesis protein OpgD"
                     /protein_id="HDV1986382.1"
                     /translation="MDRRRFIKGSMAMAAVCGTSGIASLFSQAAFAADSDIADGQTQR
                     FDFSILQSMAHDLAQTAWRGAPRPLPDTLATMTPQAYNSIQYDAEKSLWHNVENRQLD
                     AQFFHMGMGFRRRVRMFSVDPATHLAREIHFRPELFKYNDAGVDTKQLEGQSDLGFAG
                     FRVFKAPELARRDVVSFLGASYFRAVDDTYQYGLSARGLAIDTYTDSKEEFPDFTAFW
                     FDTVKPGATTFTVYALLDSASITGAYKFTIHCEKSQVIMDVENHLYARKDIKQLGIAP
                     MTSMFSCGTNERRMCDTIHPQIHDSDRLSMWRGNGEWICRPLNNPQKLQFNAYTDNNP
                     KGFGLLQLDRDFSHYQDIMGWYNKRPSLWVEPRNKWGKGTIGLMEIPTTGETLDNIVC
                     FWQPEKAVKAGDEFAFQYRLYWSAQPPVHCPLARVMATRTGMGGFPEGWAPGEHYPEK
                     WARRFAVDFVGGDLKAAARKGIEPVITLSSGEAKQIEILYIEPIDGYRIQFDWYPTSD
                     STDPVDMRMYLRCQGDAISETWLYQYFPPAPDKRQYVDDRVMS"
     gene            52594..52818
                     /locus_tag="RHX21_001160"
     CDS             52594..52818
                     /locus_tag="RHX21_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415943.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcH family protein"
                     /protein_id="HDV1986383.1"
                     /translation="MFPEYRDLISRLKNENPRFMSLFDKHNKLDHEIARKEGSDGRGY
                     NAEVVRMKKQKLQLKDEMLKILQQESVKEV"
     gene            52881..53417
                     /gene="rimL"
                     /locus_tag="RHX21_001161"
     CDS             52881..53417
                     /gene="rimL"
                     /locus_tag="RHX21_001161"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12-serine
                     acetyltransferase"
                     /protein_id="HDV1986384.1"
                     /translation="MTETIKVSESLELHAVAENHVTPLYQLICKNKTWLQQSLNWPQF
                     VQSEEDTRKTVQGNVMLHQRGYAKMFMIFKEDELIGVISFNRIEPLNKTAEIGYWLDE
                     SHQGQGIISQALQALIHHYAQSGELRRFVIKCRVDNPQSNQVALRNGFILEGCLKQAE
                     FLNDAYDDVNLYARIIDS"
     gene            complement(53412..54392)
                     /locus_tag="RHX21_001162"
     CDS             complement(53412..54392)
                     /locus_tag="RHX21_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LbetaH domain-containing protein"
                     /protein_id="HDV1986385.1"
                     /translation="MRKYRLSEEQRAFSYQEDGTKKNVLLRQIIAISDFNDVIAGTAG
                     GWIDRETVLAQEGNCWIYDQNAIAFGGTVISGNTRITGTSVLWGEVYATDNVWIDNSE
                     ISQGAYISDSVTIHDSLVCGQCRIFGHALINQHSMIVAAQGLTPDHQLLLQIYDRARV
                     SASRIVHQAQIYGDAVIRYAFIEHRAEVFDFASIEGNEENNVWLCDCAKVYGHAQVKA
                     GIEEDAIPTIHYSSQVAEYAIVEGNCVLKHHVLIGGNAVVRGGPILLDEHVVIQGESR
                     ITGAVIIENHVELTDHAVVEAFDGDTVHVRGPKVINGEERITRTPLAGLL"
     gene            54516..55508
                     /gene="tehA"
                     /locus_tag="RHX21_001163"
     CDS             54516..55508
                     /gene="tehA"
                     /locus_tag="RHX21_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate transporter/tellurite-resistance
                     protein TehA"
                     /protein_id="HDV1986386.1"
                     /translation="MQSDKVLNLPAGYFGIVLGTIGMGFAWRYASQVWQVSHWLGDGL
                     VILAMIIWGLLTSAFITRLIRFPHSVLAEVRHPVLSSFVSLFPATTMLVAIGFVPWFR
                     PLAVCLFSFGVVVQLAYAAWQTAGLWRGSHPEEATTPGLYLPTVANNFISAMACGALG
                     YTDAGLVFLGAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLSV
                     NGGEGDTLAKMLFGYGLLQLLFMLRLMPWYLSQPFNASFWSFSFGVSALATTGLHLGS
                     GSDNGFFHTLAVPLFIFTNFIIAILLIRTFALLMQGKLLVRTERAVLMKAEDKE"
     gene            55505..56098
                     /gene="tehB"
                     /locus_tag="RHX21_001164"
     CDS             55505..56098
                     /gene="tehB"
                     /locus_tag="RHX21_001164"
                     /EC_number="2.1.1.265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance methyltransferase TehB"
                     /protein_id="HDV1986387.1"
                     /translation="MIIRDENYFTDKYELTRTHSEVLEAVKVVKPGKTLDLGCGNGRN
                     SLYLAANGYDVDAWDKNAMSIANVERIKSIENLDNLHTRVVDLNNLTFDRQYDFILST
                     VVLMFLEAKTIPGLIVNMQRCTKPGGYNLIVAAMDTADYPCTVGFPFAFKEGELRRYY
                     EGWERVKYNEDVGELHRTDANGNRIKLRFATMLARKK"
     gene            56401..57069
                     /locus_tag="RHX21_001165"
     CDS             56401..57069
                     /locus_tag="RHX21_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3313 domain-containing protein"
                     /protein_id="HDV1986388.1"
                     /translation="MRTTSFAKVAALCGLLALSGCASKITQPDKYSGFLNNYSDLKET
                     TSATGKPVLRWVDPSFDQSKYDSIVWNPITYYPVPKPSTQVGQKVLDKILNYTNTEMK
                     EAIAQRKPLVTTAGPRSLIFRGAITGVDTSKEGLQFYEVVPVALVVAGTQMATGHRTM
                     DTRLYFEGELIDAATNKPVIKVVRQGEGKDLNNESTPMAFENIKQVIDDMATDATMFD
                     VNKK"
     gene            complement(57087..57433)
                     /gene="tnpA"
                     /locus_tag="RHX21_001166"
                     /pseudo
     CDS             complement(57087..57433)
                     /gene="tnpA"
                     /locus_tag="RHX21_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604919.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
BASE COUNT        14135 a        13685 c        15105 g        14508 t
ORIGIN      
        1 atgcctttat tgtcacagat tttattttct gttgggccat tgcattgcca ctgattttcc
       61 aacatataaa aagacaagcc cgaacagtcg tccgggcttt tttttagaat tggataatcc
      121 ttatccagag catttaatcg gtgttgcttt tttccgcttt tccggccatt tgtgccagga
      181 agtcatagcg tttttgcaaa tcagctgcag catctttcca taactgttct gccacttctg
      241 gctgctgcga attcagccga cggaaacgtt gctcgtgaag taacgtttct tccagtgcta
      301 ctgacggcgg gcgtgaatcc agcgccagcg gcagtttgcc ttcatcggca cgacgcggat
      361 cgaagcgata tagcggccag aagccggtag ctgtgagttg gcgcatctgg tcgtggctga
      421 gtgccagatc gtaaccatgc tcttcacatg ggctataagc gatgatcagc gatggccccg
      481 gatacgcttc cgcttcctga atcgctttca ccgtctggtt gagctgcgcg ccgagagaaa
      541 tctgcgccac ataaacatga ccgtacatca tcatactgac gccaagatct ttacgcgctt
      601 tacgtttgcc gtgctcgcca aatttagtta ctgcacccag cggtgtcgct ttcgacgcct
      661 gaccaccggt gttggaatag cattgcgtat ccagcaccag aatgttgacg ttttccgtca
      721 aacccaatac atgatccaga ccgccaaagc cgatatcgta agcccagcca tcaccaccaa
      781 tcagccagat tgatttttcc accagtgcat ctgcgtcacg cagcagttca tgtgcttcgg
      841 caacatcgtt gagttgctgg cgtaaagctg cgacctgttc tcgacgaacc tctggcgtag
      901 cgtctgattt caacgctgtc agtaattccg ccgggatttt atcggcaaat tgatccagca
      961 gacgcagcac gcggacacgg tgttgatcga ccgtcaggcg gaaaccaagg ccaaattcgg
     1021 cattatcttc aaacagagag ttcgcccatg ccggcccacg accgttggca tcggtggtat
     1081 acggtgtaga gggcaggtta ccgccataaa ttgaagaaca gccggtggcg ttagcgatca
     1141 acatccggtc gccatagagc tgagtcagca atttaatata cggcgtctcg ccacaaccgg
     1201 agcaagcacc tgaatattca aacagcggtg taatcagctg cgatgtacga atatcaatac
     1261 gttccagttt gctacggtcg atttctggca ggttgaggaa gaaatcgtaa ttgattttct
     1321 cttcttcgac atgttccagg cgcgacatca tattgatggc tttaatctct ggattctgac
     1381 ggtctttcgc cgggcaaact tcgacgcaca ggttacaacc ggtgcaatct tccggagcca
     1441 cctgcaagac atatttctgc ccgcgcatat cacgcgattt cacatccagc gaatgcaggc
     1501 tggcaggggc gttttccatc gcttcaggcg gtaccacttt tgcgcgaata gctgagtgtg
     1561 ggcaagcggc gacgcagtgg ttacattggg tacagagttc ctctttccag atggggatct
     1621 cttcggcgat attgcgtttt tcccagcgag tggtgcccat cggccaggtg ccgtctggcg
     1681 gcagcgccga aacggggagg gcatcaccaa gccctgcgag catcgctgcg gttacggttt
     1741 tcacgaaatc aggggcggca tcggaaacca ctggcggtcg attggcgctg tgcggattta
     1801 ccggttgcaa cggaacttct tctacggatt cacgcgccag cgccagagcc tgccagttgc
     1861 gttccaccag atcctggcct ttgctactgt aacttttggc aatcgcaccc tgcaattctg
     1921 cgagggcgct atcgccaggc agaatttgcg tcagatggaa aaaagccatc tgcatgacgg
     1981 tattaatacg ggccgccagg ccacattcgc gggcgatttt cgccgcgtta atcacataga
     2041 agcgcgcttt tttctgattt agcacggcct gaacttcctg cggcaagcgc gaccacactt
     2101 catctgcgct gtacggcgtg ttgagcagga aaatgccgcc aggttttaaa cgctcagcca
     2161 tctgatattt atcgataaac tgcaactggt ggcagccaac aaaatcagcc tgggaaatga
     2221 gataagcgga acgaatcggc tgttcgctca cgcgaaggtg agaaaccgtc aggccgcccg
     2281 cctttttgga gtcgtaaaca aaatagccct gtgcgtacca cggcgtggaa ttaccgataa
     2341 tcttgatatt gtttttggtc gcggaaacgc tgccatcact accaaggcca taaaacaagg
     2401 cttccagttt cgccgagttt ggcagggtgt tttccggcaa cggcagtgac agattggtca
     2461 catcatcgta aataccaacc gtaaagcgcg ctttcggttt agccgcgttg agctcggaaa
     2521 ataccgccag tacacagtcc gggccaaatt ctttggatga aagaccatag cgcccaccaa
     2581 tgacacgggg cagagtttcg cgctcgccat tattaaaggc ttctgccagt gcggtcatta
     2641 catccagata gagcggttct gcctgggcac cgggttcttt ggttctgtcc agtaccgcca
     2701 cgctgcgtac ggatcccggc agagcttgca gcaagtgttt ggcggagaag ggacggtaca
     2761 ggcgaacttt cagcacgcca actttttcgc cacgggttag caattcatca accacttctt
     2821 cacaggtgcc aatggcagag cccatcagga taatcacccg ttccgcttgc ggatgcccgt
     2881 aatattcaaa cggctgatac tgacgacctg tcgcggcaga gaaatcattc atcgcctgtt
     2941 caacatggtc atagaccgcg tcgtaccatg ggttggtggc ttcgcgagac tggaaataag
     3001 tgtcaggatt ggcggacgta ccgcggatca ccggatgttc cgggttgagc gcccgggcgc
     3061 gatgagcatc aatttcggcc tgcggcatga gatcaagaat agtgtcatcg gccagcggga
     3121 caattttatt gatttcgtgg gacgtgcgga aaccatcaaa gaaatgaata aatggcacgc
     3181 ggctcttcag cgttgcgatg tgcgaaatga gagcaaaatc ttgcgcttcc tggacgttag
     3241 ccgcacacaa catcgcgcaa cccgtctggc gcaccgccat aacgtcggaa tgatcgccaa
     3301 aaatagaaag tgcatgtgtg gcaacggtac gtgccgctac atgcaggaca aatggcgtca
     3361 gttcgcctgc cagtttgtac agcgtcggga tcatcagcag caaaccctgc gatgacgtaa
     3421 acgatgttga aagggcaccc gtctgcaaag cgccatgcac ggtagcgata gcacccgctt
     3481 ccgactgcat ttcaactacg cgtggtgtgt ctccccaaac gttctttaag ccgtttccgg
     3541 cccaggcatc agcctgttct gccatcgtgg aactgggggt aatagggtag atggcgataa
     3601 cttcactggt gcgaaacgcc accgaagcaa ccgcgccatt accgtcaata gtaatcatat
     3661 gacaccctta cattgcgcaa atgaggggcg cacgaaattg ctgcgcgccc agtagtaatc
     3721 cttcaatttt agcaaatggc tttcttctgc attttcgctt ttgtgtcccc cacatcagcg
     3781 taatgaatgt tttgatcaaa cagagggcaa aaaaatagcc ataaaaaagt aaaaatgcgg
     3841 ggcaacgcgc aggacagctc tcgacgtcgc cctctgtgct gcctattatt tatggcggtg
     3901 tcgtttggct tgaagatcag aggaagaaaa gatgcgagca gcgttttggg tagggtgtgc
     3961 cgctttattg ttgtcggcgt gtagtagtga acctgttcag caggcgactg cggcgcacgt
     4021 agcgccaggt ttaaaagcgt cgatgtccag tagtggagaa gcaaattgtg caatgatcgg
     4081 cggttcgctt tctgttgccc gtcaactgga tggtacggcg attgggatgt gtgcattacc
     4141 caacggcaaa cgctgtagtg aacagtcact tgccgccggg agctgtggca gctattaatt
     4201 cattaaatcc gccagcttat aagttaatgt ctgtttcgcg gtcgccagcg ttaactggtt
     4261 cgcggtcaga tccacttgtg caccttcttt cagcatttcg ctaatggtgt tatcgagttc
     4321 attaagctgc gggttagcgc acatcatacg ggtcattgcc agccctttgg ctgtcagttc
     4381 accattagac agtttgcctt caccgctaaa gcggttacac atgctgccgg aaatcatcat
     4441 tttttcacca aagctgattt ctggcggatt tttatcgttg gtcacgggct taccgtttac
     4501 gctttccagc acaaaacgat gatgctgtaa ctgttctggc gttacagcaa ttttgtcatt
     4561 acttacacat cccgccatca gcaggcttag cgcaacgagc gcggctactt tcttcattgt
     4621 ggttctcaat tacagtttct gactcagggc tattttaaga atagaggatg aaaggtcatt
     4681 ggggattatc tgaatcagct cccctggaat gcaggggagc ggcaagatta aaccagttcg
     4741 ttcgggcagg tttcgccttt ttccagattg cttaagtttt gcagcgtagt ctgagaaata
     4801 ctggtcagag cttctgctgt caggaatgcc tggtgcccgg taaatagcac gttgtggcag
     4861 gcagacaggc gacggaatac gtcatcctga attacgtcgt tggatttatc ttcaaagaat
     4921 agatcgcgtt cgttctcata cacgtccata cccaacgaac caattttctg atttttcagc
     4981 gcttcaattg ctgcctgaga atcaatcaat gcaccgcgac tggtattgac gatcatcacg
     5041 ccatttttca tctgatcgaa ggcggcttcg ttcaacagat ggtagttttc cggtgtcagc
     5101 gggcagtgca gagagataac gtctgattca gagaacaggg ttggcagatc gacatactcc
     5161 acaccgagtt ccagcgccgc tgcacttgga tacggatcga acgccagcag acgcatacca
     5221 aaacctttca gaatgcgcag catcgccaca ccgattttac cggtaccgat aacgcctgcc
     5281 gttttgccat acatagtaaa gccggtcaga ccttccagag agaagttagc gtcacgggta
     5341 cgctgatacg cgcggtgaat acggcggttc agcgtcatca tcataccgat ggcgtgttca
     5401 gcaacggcct ctggatcata ggctggaaca cggactactt tcagccccag ttcttttgcc
     5461 gcgtcaaggt cgacgttatt gaaaccggca cagcgcaggg cgatatattt aacgccgtgc
     5521 tttttcagct cttccagcac cgggcggctg ccgtcatcgt ttacgaaaat acataccgct
     5581 tcgcagccat tggcagtttt agcggttttt tccgtcagca gaaagtcaaa aaattccagc
     5641 tcaaagccaa aggactcgtt cacctgttgc aggtacttct tgtcgtactg ttttgtgcta
     5701 taaacggcga gtttcataag actttctcca gtgatgttga atcacattta agctactaaa
     5761 aatattttac aaaatttcaa atataattga aagctatggc gatattgaaa aattcatcaa
     5821 caactatgct tagtgtaggc gcaaccttca actgaacggt taaacatgcc acaatacccg
     5881 tattgaatgc ttaatttttc gctaaatcag gatattaact acccatgctg ggtaaatata
     5941 aagccgttct cgcgctgtta ttactgatta ttcttgtgcc gttgacgctg ctgatgacgc
     6001 tcgggctgtg ggttcccacg ctggcgggca tctggctacc gctcgggaca cgtattgcat
     6061 tagatgaaag cccacgcatt acgcgtaaag gtttaatcat tcccgatctc cgttatctgg
     6121 tgggagattg tcagcttgcg catatcacca acgccagcct ttcacatccc agccgctggt
     6181 tattgtacgt cggcatggta gaacttgatt ctgcttgtct ggcgaaattg ccgcagacgg
     6241 agcaatcgcc agctgctcca aaaaccctcg cgcagtggca gtccatgctg cctaacacct
     6301 ggatcaatat cgataaactg attttttctc cctggcagga atggcaggga aaactctctc
     6361 tcgcattaac ctctgatatc cagcaactgc gttatcaggg cgaaaaagtt aaatttcaag
     6421 gccaactgaa agggcaacaa cttacagtca gcgaactgga tgtcgtcgcg tttgaaaatc
     6481 agccgccggt taaactggtg ggggaattta ctatgccgct cgtgccggat ggacttcctg
     6541 taagtgggca tgctactgcg acgttaaact tgccgcagga accgtcactg gtggatgcag
     6601 agctggactg gcaggaaaat agcgggcaat tgattgtgct ggcacgggat aacggcgatc
     6661 cgttgctcga tttgccgtgg caaattactc gtcaacaatt gaccgtaagc gatggtcgct
     6721 ggagttggcc gtatgcaggt tttcctttga gtggccgact gggtgtcaaa gtcgacaact
     6781 ggcaggcagg gcttgagaac gctctgatca gcggacgact gagtgtgctg acccaggggc
     6841 aagcgggtaa aggcaacgcg gtgctaaatt ttggcccagg aaaattaagc atggataaca
     6901 gtcagttgcc tctgcagctg accggtgaag cgaaacaggc ggacctcatt ttatatgccc
     6961 gtttacctgc gcagctaagt ggaagtctgt ctgacccaac gctgaccttt gagccaggcg
     7021 cgttacttcg ttcaaaggga agagtcatcg attcgctgga catcgatgaa atccgctggc
     7081 ctttagcggg tgtaaaagtc acccaacgtg gtgttgacgg acgtttgcag gccattttgc
     7141 aggcgcatga aaatgaactg ggcgatttcg tgctgcatat ggatgggctg gcgaatgatt
     7201 ttctccctga cgcgggccgc tggcagtggc gctactgggg aaaaggcagt tttacaccga
     7261 tgaatgccac ctgggatgtc gcaggaaaag gtgaatggca tgacagcacg attacgctga
     7321 ccgacctctc caccggtttc gaccagttac aatacggtac gatgacggta gaaaagccgc
     7381 gattaattct cgacaagccc gtcgtctggg tacgtgacgc acagcatccc tccttcagcg
     7441 gcgcgctgtc actggacgcc gggcaaacgc tgttcactgg cggcagtgtg ttaccgccat
     7501 caaccttaaa atttagcgtc gatgggcgcg atccgacgta tttcctcttt aaaggcgatt
     7561 tacatgctgg tgagattggc ccggttcggg taaatggtcg ctgggacggt attcgtctgc
     7621 gcggtaacgc ctggtggcca aaacaatcac tgactgtatt ccagccgctg gtgccacccg
     7681 actggaagat gaacttacgc gatggtgaac tgtatgctca ggttgcattt tctgctgcgc
     7741 ctgaacaagg attccgcgcg ggaggacacg gcgtgttgaa aggcggtagt gcctggatgc
     7801 cagataatca ggttaacggt gtcgattttg tcctgccttt ccgttttgcc gatggagcct
     7861 ggcatctggg gactcgcggc cccgttacgt tgcgaattgc cgaagtgatt aatctggtga
     7921 cagcgaaaaa tattacggct gatttgcaag ggcgttatcc gtggactgaa gaagaaccct
     7981 tgctgttgac tgatgttagc gtcgatgtgt taggcggtaa cgtactgatg aaacaattac
     8041 gtatgccgca acatgacccg gcgctgttgc ggctgaataa tctctcatcc agcgaactgg
     8101 ttagcgccgt caatccgaaa caattcgcca tgtccggggc atttagtggt gcattgccgt
     8161 tatggctaaa caacgaaaaa tggatagtga aagatggttg gctggcaaat agcgggccaa
     8221 tgaccttgcg gctggataaa gacaccgcag atgcggtggt gaaagacaat atgactgcgg
     8281 gttcagcaat taactggttg cgctatatgg aaattagccg gtcatcgaca aaaattaact
     8341 tagataatct cggtttatta accatgcagg ccaacattac aggtaccagt cgcgttgatg
     8401 gtaaaagcgg tacggtaaac cttaattact atcatgaaga gaatattttt acgctgtggc
     8461 gcagtttacg ctttggcgat aatctccagg catggttgga gcagaacgca cgtctgccgg
     8521 gaaatgactg tccgcaagga aaagagtgtg aggaaaaaca atgaaaattt tactggctgc
     8581 gttgacgtca tcttttatgc tggctgcctg tacgccgcgt attgaagtcg ctgcgcccaa
     8641 ggaaccgatc actatcaata tgaacgttaa aattgagcat gagatcatca tcaaggcaga
     8701 caaagatgtc gaagagctgc ttgaaactcg tagcgatctt ttctgaggcg atgatgaaga
     8761 aaacattact tctttgtgcg tttcttgttg ggctggtaag cagcaatgta atggcattga
     8821 ctctggatga agccagaact caggggcggg taggtgaaac attttatggt tatctggttg
     8881 cgctgaaaac ggatgctgaa acagagaaat tagtaaccga cattaatgcc gaacgtaaag
     8941 cgagttacca acaactggca aagcaaaata atgtgtctgt agatgatatc gcgaaactcg
     9001 ccgggcaaaa gctcgtagct cgggccaaac cgggggaata tgtacaaggg ataaacggta
     9061 aatgggtgcg aaaattttaa tagcaaaacc gcaatatcgg gataacgcta caggagaaag
     9121 cgattgatct attttcctga aacaaggtga atattcaaaa actcctgtca aattgccttt
     9181 cgccctgaaa aatgcatagt caaatatctg ttttaactaa ttggcgttgc agtacacaca
     9241 acgccaatta gttagcggaa tttacgtcga tactcgcctg gcgtcatccc aaagcgttgc
     9301 ttaaataccg ttgaaaaatg actctggtca gaaaatcccc aatgaaagcc gatgcctgcc
     9361 agtttttcat catctgcggc atggcgaatc gcatctgcac aaaaatcgag acgacggtta
     9421 cgaatatatt gcgcgactac caaaccttta tcggcaaaca ttcggtacaa actacgtact
     9481 gacatacctg tctctccggc tatccactcc gggcgtaata tctcttcgcg aatattatcg
     9541 tctatcaacg taaccacttt ttgaaactga cgttcacgac gaggttgaac agattcccgc
     9601 tgatgaagta ccgggcgcag cagacacacc atcgcctgta gcgcagcttc actttctgtt
     9661 tcagaaagtg ccggattatt catgctctcc tgtaacaggc gatgactgag ttgcaccatg
     9721 ggtaagtcag cgtccagtct ttctgcgcag acaggttttt gatggggaaa atattgttcc
     9781 agcagagtgc gtggcaaaag taatgaaatc tgtttagaag actcctgcca gtaaagcgaa
     9841 caggggcgtg aggcatcgag taacgtaata tcgccagcgc caatctgcac ctgacgctca
     9901 tcctgctcca ttattgcctg accactaagc tgaaaaacgg tgtaaaacca ggcatcgtcg
     9961 ctgcctttta cttcctgcca ggtgcgggat aaattcaccc cgctggttgt cacggtactc
    10021 agctttagtc ctttggcaaa atgcgtgtcc agtacacccg tgtaacgctc agtcagcagg
    10081 cgtccggtaa aatttccgca tacctgattg atttgggaaa gccattgctg aaactcatta
    10141 tccactgcgg ggttcatggc acgttttcgc tctgtgaaat gtatttttat tgttgcattt
    10201 gtgttgcaat aaacgaagct aatgagcctg actataggaa ataagtcttg tcaggcatag
    10261 agacataagc ggttattgtc acgatttgcg gagcttgtca cagctgacaa agcgaatgtc
    10321 acagcgaaaa aagtgacttt tcttgtcgct gcgtacactg aaatcacact gggtaaataa
    10381 taaggaaaag tgatgacaga gccgcatgta gcagtattaa gccaggtcca acagtttctc
    10441 gatcgtcaac acggtcttta tattgatggt cgtccaggcc ccgcacaaag tgaaaaacga
    10501 ttggcgatct ttgatccggc caccgggcaa gaaattgcgt ctactgctga tgccaacgaa
    10561 gcggatgtag ataacgcagt catgtctgcc tggcgggcct ttgtctcgcg tcgctgggcc
    10621 gggcgattac ccgcagagcg tgaacgtatt ctgctacgtt ttgccgatct ggtggaacag
    10681 cacagtgagg agctggcgca actggaaacc ctggagcaag gcaagtcaat tgccatttcc
    10741 cgtgcttttg aagtgggctg tacgctgaac tggatgcgtt ataccgccgg gttaacgacc
    10801 aaaatcgcgg gtaaaacgct ggacttgtcg attcccttac cccagggggc gcgttatcag
    10861 gcctggacgc gtaaagagcc ggttggcgta gtggcgggaa ttgtgccatg gaactttccg
    10921 ttgatgattg gtatgtggaa ggtgatgcca gcactggcag caggctgttc aatcgtgatt
    10981 aagccttcgg aaaccacgcc actgacgatg ttgcgcgtgg cggaactggc cagcgaggct
    11041 ggtatccctg atggcgtttt taatgtggtc accgggtcag gtgctgtatg cggcgcggcc
    11101 ctgacgtcac atcctcatgt tgcgaaaatc agttttaccg gttcaaccgc gacgggaaaa
    11161 ggtattgcca gaactgctgc tgatcactta acgcgtgtaa cgctggaact gggcggtaaa
    11221 aacccggcaa ttgtattaaa agatgctgat ccgcaatggg ttattgaagg cttgatgacc
    11281 ggaagcttcc tgaatcaagg gcaagtatgc gccgccagtt cgcgaattta tattgaagcg
    11341 ccgttgtttg acacgctggt tagtggattt gagcaggcgg taaaatcgtt gcaagtggga
    11401 ccggggatgt cacctgttgc acagattaac cctttggttt ctcgtgcgca ctgcgacaaa
    11461 gtgtgttcat tcctcgacga tgcgcaggca cagcaagcag agctgattcg cgggtcgaat
    11521 ggaccagccg gagaggggta ttatgttgcg ccaacgctgg tggtaaatcc cgatgctaaa
    11581 ttgcgcttaa ctcgtgaaga ggtgtttggt ccggtggtaa acctggtgcg agtagcggat
    11641 ggagaagagg cgttacaact ggcaaacgac acggaatatg gcttaactgc cagtgtctgg
    11701 acgcaaaatc tctcccaggc tctggaatat agcgatcgct tacaggcagg gacggtgtgg
    11761 gtaaacagcc ataccttaat tgacgctaac ttaccgtttg gtgggatgaa gcagtcagga
    11821 acgggccgtg attttggccc cgactggctg gacggttggt gtgaaactaa gtcggtgtgt
    11881 gtacggtatt aatctggttc gctcataagt aaaaaacggc acctggtgcc gtttttttgt
    11941 ctgaaacaat cacttatctt tcttcagcgc ccctagcgtt ggcgtttcgt caaagaagtt
    12001 ccatggttta agcagagtat gtacccattc ggtcggcata atcggccact cttcggcgcg
    12061 ggccacatgt gtggtgccgg tggtcatcca gacaacggcg tcggtgttgt ccagcgactc
    12121 gttatcttta ctgtattgtc caagaccggt gtcatgagta gaacggttcg gatatttgcc
    12181 ttccgggaaa cgctcgccag gatgataacg cgttacccaa agctgcttgt ccataaagct
    12241 taaacgatga tagatccact cgtccggcgc gaactgggca ccttttgcta ccgggtgagt
    12301 accacctgca taaggaataa tttgatagga aactggattg cccatgcggt tctctttgtt
    12361 cgggttactc aacagacgaa tcgtgcccgg atcaaacttc tgcgcggcat cctgttcatt
    12421 gccgatgttg tactgattaa cttgcatggt actggtgcgt gggccaccgg cagtattcgg
    12481 ttttaccacc gggtccatcg ccaccaggct gttattctcg ccatctacat ccagatcgag
    12541 gcggaaatta taaatatgtt ggtgtgtagt acccacgata ttgtgatcga taagcgtgcc
    12601 gtagcgcgtg tcatctttcg ccgtctcatc gtgcatggtt ttcgctttaa cacctttcac
    12661 cgcttcgatg cccgtagcac cggcatcaat gccaatagtg ccgttttcat ggaagatcca
    12721 gtcaaaaatg tagtcatagt tacccactgt actgatccag cgcaccacca actcccggcg
    12781 ttcggtactg acgttgggct ggcccatttc ctgatgctta tactccggcc cggcataacg
    12841 ttcaaatacc gcgatagcac gagggatctc catcggtacg ccagtgtagt cggcgatggt
    12901 ttcattcagg agcactgcgt tagagggtgc atctttgcca cgtgcaattg gcgaggttag
    12961 cgtgcccata ccgtagtcac cagagtccag atacgcttta aagtaccagc caatatcagg
    13021 atcaccgtaa ggcacaatca tgccgccgag agaaccttcg tacatgactt tgcgtttggt
    13081 gccattgtcg ttataagtca cggtggagat cataggtccg acgcgcgagt tcatgctgag
    13141 gtgaaaatcc cagttccgcc agtgaatcat atcgccagta atggtgtaat ttttaccttc
    13201 aggctcaatg atttgcatag gcttaactgc cggagcaacg cggtcacggc catcaaatgg
    13261 gcgtgcggtc attggcaccg gaactactgc accttcttca atcttaacga tttttttctg
    13321 ttctaaatca acgaccgcca ccaggttttc gatgggatgt gcccagtagt tgccatcacc
    13381 gacatcaaga tagctgatga ctttgagcaa ccgggcatct tgtttcaggc catctttacc
    13441 atcgaaataa cctacggtca gcggcgtggt aatcactttc ttcgcatcag taataccgcg
    13501 cttcttcacg gcagcggcaa attcttcact gttgttaata atgttctgca cactggcgaa
    13561 atcatccagc aacaccatac cgtgggcgtc tttaatgggt tgccaggaga gcagtttgtt
    13621 gttttgcaga tccaccaccg cttcgatgat atgtttgccg tcgagcataa tgacgtcggc
    13681 tttgcgtggc tggtcaaccg gtttgttttc cagcgcaaac gcccagacag cttctttatc
    13741 tggcggtagc agggagatct cagtaaaacg ggtattgggt ttgaagtccg cggaagcttt
    13801 aacaatttca acggcctgtt taatttcgtc cgcagttagc gcattaagtg ggtgagggcg
    13861 cttttctacc tgaaaggttt gatccagccc ggactggaaa acatcgttaa taaaggtgtc
    13921 agaaacccag gctttattgt ctttcatcac taccggtact tgcagtgcca gagactgacc
    13981 attaacaatt gctgtttgcg caccaggctt cactttcacg tacgcgccat ctttaatcag
    14041 ggtaaagatc tgggcgtagt cgtcccactg cacatcggca ccaaattctt taagcgtttt
    14101 atccattggc accatatgcg cttcaccacc gtgggcaaat accggcgctt gccaggcgaa
    14161 acttaaggcg actgccaacg ccagggctgt tttacgggca gaatacagag aggggcttcc
    14221 cattattaac ctcgtcagat gttgtgttct tgttagcaac cgcgctctgt gggcggttta
    14281 gtcaggttca cattatcagt actgatgtaa aggggattgc ctgcacctgc caggttgttt
    14341 ggcaggtgtg ccagcttttc atacagtggg tgccctgaaa atacagatac acatcatgca
    14401 taacgtgaca acgtcacaaa atttggtgaa ataaaagggc aactattcgc cgttgccctt
    14461 cattcaccga ttaatcgaca aaatcaccgt gctgcctggc caccagcgtc agaattgaat
    14521 acagcgccac cggggtttga tgctgattga atacctctac cgcccattcc accacacctg
    14581 ttggtttttc ttctgcgcta cgctgttttt tcagcgtctt gcgcttacag gtgagacgca
    14641 cctggatggt atcgcctggc tttacgggtt cgataaagcg caagttttcc agcccataat
    14701 tagcaatgac cggaccgaca ccggcatcga caaacagacc cgcagccgca gaaagcacaa
    14761 aatacccatg caccacacgc tcaccgaaaa tagattcggc agcagcaatc ttatccatat
    14821 gcgcatagaa atgatcgccg ctgaggcaag caaagttaac aatatcggcc tctgtcattg
    14881 tgcggcgggg agtcaacagg ctgtcgcctg gttgcagctc ctcaaaatat ttgcggaacg
    14941 gatgaatacg atcttcttcg actttcgcac cgcgcaccca ctgtttactg atagcggcaa
    15001 gcatcgtcgg actaccctga acagcggttc gctgcatgta atgtttcacc gctcgtaaac
    15061 cacctaattc ttcaccgcct cctgcgcgac caggcccacc atgtaacagt tgtggcagtg
    15121 gggagccatg cccggtggat tcttttgccg attcctcatt gaggatctga attcgcccat
    15181 gcgtacgtgc cgcgtcggta ataaactgac gcgcaatttg cggatcagcc gtcaccagcg
    15241 ttcccgcaag gctaccgccg cctgcacaag ccagttgcag agcatgtcgc tggttttgtg
    15301 ctggcatcag cgttgcgaca gggccaaagg cttctgttgc atgtaccgcc ggtgtttcat
    15361 ccggctgcgg acagtacaat aaggttggcg ggaagaaggc acccgcagca gataaatccg
    15421 cctgaccacc gaggcgaatc tcgcatcctg cagccagcaa tatgttcact ttttcctgca
    15481 catcggcacg ctgctcagca tttaccagtg cgcccatttt cacgccttcc tgagcaggat
    15541 caccgaccac gactttctgt aatcgcgcaa ccagaacatc actgacagca ttaaccaatg
    15601 cctgcggcac aataatccgc cggattgccg tacatttttg cccggctttt gtggtcatct
    15661 cacgcacaac ttcacgaata aacagcgcaa actccggttg atccggggtg acatcttcgc
    15721 ccagtacgca gcagttcagg gaatcagctt ccatagtgaa ggggatagat ttggcgacga
    15781 tatttggctg aactcgcagc atctgtccgg tcgccgctga ccccgtgaaa gtcaccacat
    15841 cctggctgtc cagatgatcc aaaaggtcgc ccgcactacc gcagatcaga ctaattgcgc
    15901 cttcgggaac aagaccacta tcgacaattg atttcaccat cgcctgagtc agttgggccg
    15961 tcgcggtagc tggtttgatg atggctggca ttccgcccag ccacgttggt gccagctttt
    16021 ccagcattcc ccagcagggg aagttaaagg cgttaatatg cactgccacg cctgactttg
    16081 aggtcagtac atggcgcgcg gcaaatccac cttctttcga taaggggatc aattcatctt
    16141 ccggccacag cgtatcgtca ggcagctccc ggctaccgag gctggcgtaa gtaaataacg
    16201 tcccaatgcc accttcaata tcaacccaac tgtctgcccg cgttgcgcct gtttgcgcag
    16261 aaagagcata gaagcgctct ttttcactca gcagatgttt agcgaccgct ttaagcatcg
    16321 ccgcacgttc gataaaggtc atagcgcgaa gggcgggggc acctttttca atggcaaact
    16381 ggcgggcagc cgccatatca agaccttcac tggtcacttc ccataacgcc tcgccgctaa
    16441 tagcgtggtg aatcaaacgg ctacggcccc ggccagactg ccaggtaccg gataagaaac
    16501 tggctaactg ctgcatcgct actctccaga tgtttcacat ttctgttgct aatagttaaa
    16561 tcgcgaatca taaaaagcaa gggttctttt aacgaaatgt taactatgcg atctgtatag
    16621 caactgcgga aaacattaat gcactgataa ataatgattt ataaaaatag ggtgcgaaat
    16681 ccgtcacagt tcaagcatac aaaatttgtg attttagtta accattgtgt aactttcata
    16741 aaacaacgtg attcgttttt ttaattaatt cacgaaaact ggaatcgtaa aggtgatgac
    16801 gtgacccaag aagaacgctt tgagcaacgg atagcccagg aaacggctat cgagccgcag
    16861 gactggatgc ccgatgctta ccgaaagaca ctgatccgcc agattgggca gcatgcgcac
    16921 tccgagattg ttggtatgtt gcctgaaggt aactggatca ctcgcgcacc aaccttgcgg
    16981 cgtaaagcca ttctgttggc caaagtgcag gatgaagccg gtcatggtct gtatctctat
    17041 agcgccgccg aaacactggg ctgcgccaga gaagacatct accaaaaaat gctcgacgga
    17101 cggatgaaat attcctccat ctttaattat ccgacattga gttgggctga tatcggtgtt
    17161 atcggctggc tggtggatgg cgcagcgatc gtcaatcagg tggcgttatg ccgcacttct
    17221 tatggcccgt atgccagagc aatggtgaaa atctgcaaag aagagagttt tcaccagcgt
    17281 caggggtttg aagcctgcat ggcactggcg cagggcagcg aagctcaaaa gcagatgttg
    17341 caagacgcca ttaaccgttt ctggtggcca gccttaatga tgttcgggcc aaacgatgat
    17401 aactcgccaa acagcgccag aagtctcgcc tggaaaatca aacgtttcac caacgacgaa
    17461 ctccgccagc gtttcgtgga taacaccgtt ccacaggttg aaatgctcgg tatgaccgtt
    17521 cctgacccgg atctgcattt tgacactgaa agcggtcact accgctttgg tgagatcgac
    17581 tggcaggagt ttaacgaagt aattaacggt cgcggaattt gtaatcagga gaggctcgac
    17641 gccaaacgta aagcctggga agaaggtacc tgggtacggg aagcagcgct ggcccatgca
    17701 caaaaacaac ttgcccgtaa ggtcgcataa ggagattcaa aatgagtaat gtttactggc
    17761 cgttatacga agttttcgtg cgtggcaaac agggcttatc acaccgccat gttggcagtt
    17821 tacatgctgc cgatgagcgg atggcactgg aaaatgcccg tgatgcttac acccgtcgta
    17881 gcgaaggatg ttcaatttgg gtggtgaagg cgagtgaaat tgttgcctcg caaccggaag
    17941 aacgcggtga attttttgat ccggctgaaa gcaaggtcta tcgccatcca acgttttaca
    18001 ccatccctga tggcattgag cacatgtgag gtcggaaatg aatcagttaa cggcttacac
    18061 cttgcgcctg ggcgataact gtctggtgct ctcccagcgg ttgggggaat ggtgcggtca
    18121 cgcaccggaa ctggaaatcg atctcgcact ggcaaacatt ggcctcgatt tattaggtca
    18181 ggcacgtaac ttcttatcgt atgccgctga attagcggga gaaggtgatg aagataccct
    18241 ggccttcacc cgagacgagc gccagttcag caacttattg ttggttgaac aaccaaacgg
    18301 caattttgcc gacaccattg cacgccagta tttcatcgat gcatggcatg tggcgctctt
    18361 tacccgtctg atggaaagcc gtgatccgca actggcggcg atttctgcca aagcaattaa
    18421 agaagcgcgt tatcacctgc gttttagtcg tggctggctg gagcgactgg gcaatggtac
    18481 tgacgtatca gggcaaaaga tgcagcaggc catcaacaag ttgtggcgtt ttaccgccga
    18541 actgttcgat gccgacgaga ttgatattgc actgagtgaa gagggtattg cggttgatcc
    18601 acgcacttta cgcgcagcgt gggaagccga agtttttgcc gggatcaacg aagccacatt
    18661 gaacgtaccg caagagcagg cgtatcgcac tggcggtaaa aaaggactgc ataccgaaca
    18721 ccttggaccc atgctggcag aaatgcagta tctccagcgt gtcttgcccg gtcagcaatg
    18781 gtaacagagg agatgggtat gcaacgtctg gccaccattg caccgccaca ggttcatgag
    18841 atatgggcgc tactcagcca gatcccggac ccggagatcc cggtgctgac cattaccgat
    18901 ttaggcatgg tgcgtaatgt gacacagatg ggagaaggat gggtgatcgg ctttacgccg
    18961 acttattccg gttgtccggc aacggaacat ttgattggcg cgatacgtga ggcaatgaca
    19021 acccacgggt ttacccccgt tcaggttgtg ctgcaactcg acccggcatg gaccaccgac
    19081 tggatgaccc ccgatgcccg tgagcgtctg cgacagtatg gcattagccc gcccgccgga
    19141 cacagttgcc atgcccattt gccgccagaa gtacgttgcc cgcgctgcgc cagcgtccat
    19201 accacactta tcagtgaatt tggttccacg gcctgcaaag cattgtatcg ctgcgatagt
    19261 tgccgcgaac ctttcgatta tttcaaatgt atttgaggat gccatgacaa cgtttcattc
    19321 cttaacggtg gcaaaagtgg agccggaaac ccgtgatgcg gtgaccatta cctttgcggt
    19381 gccccagcct ttgcaggagg cgtatcgctt tcgccccggt caacatttga ccttaaaagc
    19441 cagctttgat ggtgaagaat tacgccgttg ttactccatt tgccgcagct atctgcctgg
    19501 cgaaattagt gtggcggtga aagccattga aggcggacgt ttctcccgct atgcccgcga
    19561 acacatccgc cagggtatga cgctggaggt catggtgccg caggggcatt tcggctatca
    19621 gccacaggcc gaacgccagg gccgctatct ggctattgca gcaggatcag gtattacgcc
    19681 aatgctggcg attatcgcca ccactttaca aaccgagcct gaaagtcagt tcaccctgat
    19741 ctacggtaac cgtaccagcc agagcatgat gtttcgccag gcactggcag acctgaaaga
    19801 caaatatcct cagcgtttac agttgttgtg cattttcagt caggaaaccc tcgacagcga
    19861 tctgcttcac gggcgtattg acggtgaaaa attacagtca cttggggcct cgctcattaa
    19921 ttttcgtctt tatgatgagg catttatttg tggtccggcg gcgatgatgg atgagacgga
    19981 agccgcctta aaagcactgg gaatgccaga taaaaccatt catctggagc ggtttaatac
    20041 gcctggcacg cgcgtcaaac gtagcgttaa cgtgcaaagt gacggacaaa aagtgactgt
    20101 acgtcaggat gggcgggatc gggaaatcgt gcttaatgcc gacgatgaaa gcattctcga
    20161 tgcggcattg cgccaggggg ctgatctgcc ctatgcctgc aaaggcggcg tctgtgcgac
    20221 ctgcaaatgc aaagtgctgc gtggcaaagt ggcgatggaa accaattaca gtctggaacc
    20281 ggatgaactg gccgcaggct atgtgttgag ttgccaggca ctgccgctga ccagcgatgt
    20341 ggtggttgac tttgacgcga aggggatggc atgagcgaac tgatcgtcag ccgtcagcaa
    20401 caagtattgt tgctgaccct taaccgtccc gccgcacgta atgcgctaaa taatgccctt
    20461 ctgacgcaac tggtaaatga actggaagct gcggctaccg atagcagcat ttcggtctgt
    20521 gtgattaccg gtaatgcacg cttttttgcc gctggggccg atctcaacga aatggcagaa
    20581 aaagatctcg cggccacctt aaacgataca cgcccgcagc tatgggcgcg attgcaggcc
    20641 ttcaacaaac ctctcatcgc agccgtcaac ggttacgcgc ttggtgcggg ttgcgaactg
    20701 gcattgttgt gcgatgtggt ggttgccgga gagaacgcgc gttttggttt gccggaaatc
    20761 actctcggca tcatgccagg cgcaggagga acgcaacgtt taatccgtag tgtcggtaaa
    20821 tcgttagcca gcaaaatggt gctgagcgga gaaagtatca ccgctcagca agcacagcag
    20881 gccgggctgg ttagcgacgt cttccccagc gatttaaccc tcgaatacgc cttacagctg
    20941 gcgtcgaaaa tggcacgtca ctcgccgctg gccttacaag cggcaaagca agcgctgcgc
    21001 cagtcgcagg aagtggcttt gcaagccgga cttgcccagg agcgacagtt attcaccttg
    21061 ctggcggcaa cagaagatcg tcatgaaggc atctccgctt tcttgcaaaa acgcacgccc
    21121 gactttaaag gacgctaatg atggaattca tcctcagtca tgtagaaaag ggcgtgatga
    21181 cactaacgct caaccgcccg gaacgcctga acagttttaa tgatgagatg cacgcacaac
    21241 tggcagagtg cctgaaacag gtcgagcgcg acgacactat ccgttgcctg ttacttacag
    21301 gtgccgggcg cggattttgt gctggtcagg atcttaacga tcgtaacgtt gatcccacag
    21361 gccccgcacc ggatttaggg atgtcagttg aacgtttcta taacccactg gtacgtcgcc
    21421 tggcaaaact gccaaaaccg gtgatctgtg cagtcaatgg cgtggcggca ggggctggcg
    21481 caacactggc actgggatgc gacatcgtta ttgctgcccg ttcagcaaaa ttcgtcatgg
    21541 cgtttagtaa gttaggttta gtacccgatt gcggtggaac ctggttactg ccacgcgttg
    21601 ctgggcgagc gcgcgccatg gggctggcac tgctggggaa tcaactgagt gctgaacagg
    21661 cgcacgaatg ggggatgatc tggcaggttg ttgatgatga aacgctggca gataccgcgc
    21721 aacagctggc acggcatctg gcgacacaac cgacatttgg tcttggactt atcaagcaag
    21781 cgataaatag cgctgaaacc aatacgctcg atacgcaact ggatctggaa cgtgactatc
    21841 agcgacttgc cggacggagc gcagattatc gtgaaggtgt cagtgcgttc ctggctaaac
    21901 gctcaccgca gttcacgggg aaatagcatg atgataaatg tgcaaactgt ggcagtgatt
    21961 gggagcggca ccatgggggc aggcattgct gaagttgccg ccagtcatgg acatcaggtt
    22021 ttactgtatg acatttctgc tgaagcgctg acccgcgcaa tcgacgggat acacgcgcgg
    22081 ctaaattcac gcgtgacgcg gggaaaactg actgctgaaa cctgtgaacg cacattgaaa
    22141 cgcctgatcc cggtgaccga tattcacgcg ctggcagcag cgaatctggt tattgaagcg
    22201 gcgtctgaac gtctggaagt taaaaaagcg ctctttgcac aactggcgga agtttgcccg
    22261 ccacaaacgc tattgaccac taacacttcg tcaatctcta taaccgcgat tgctgcggag
    22321 gtaaaaaatc ctgaacgtgt tgcggggctg cattttttta acccggcacc ggtgatgaag
    22381 ttggtggagg tggtcagtgg gctggcaacg gcagcggaag ttgtcgagca gttgtgtgaa
    22441 ctgacattga gttggggtaa gcagccagtg cgctgtcatt cgacccccgg atttatcgtt
    22501 aaccgtgtgg cgcgtcctta ttattccgag gcctggcggg cactggaaga gcaggttgct
    22561 gcaccagaag tgattgacgc tgcacttcgc gatggcgctg gtttcccgat ggggccgctg
    22621 gaattaaccg atctgattgg tcaggacgtc aattttgctg tcacctgttc ggtgtttaac
    22681 gctttctggc aggagcgtcg ttttttacct tcgctggtgc aacaggaact ggtgattggt
    22741 ggacggttgg gcaagaaaag tgggctgggc gtgtacgact ggcgcgcgga acgtgaggca
    22801 gttgttggcc tggaagcggt aagcgacagt tttagcccaa tgaaagtaga aaagaaaagt
    22861 gacggcgtca cggaaattga cgatgtttta ttgattgaga cacaaggcga gacggcacag
    22921 gcgctggcaa tacgactggc acgcccggtg gtagtggtcg acaaaatggc gggcaaggtg
    22981 gtgaccattg ctgcggcagc ggtgaacccg gactcagcga cccgcaaggc catttattac
    23041 ctgcaacagc agggcaaaac agtgctgcaa attgcagatt acccaggaat gctgatttgg
    23101 cgaacggtag caatgatcat caatgaagcc cttgatgcgc tgcaaaaagg cgtggcctct
    23161 gaacaggata tcgataccgc catgcgtctt ggggtgaatt atccatatgg cccgcttgcc
    23221 tggggagcgc aacttggctg gcagcgaata ttaaggctct tggaaaatct acaacatcac
    23281 tatggcgaag aacgctatcg cccatgttca ttgctgcgcc aacgagcgct tctggagagc
    23341 ggttatgagt cataaggcct ggcaaaatgc ccatgcaatg tatgagaacg atgcctgcgc
    23401 caaagcgctt ggcatcgaca ttatctcaat ggatgaaggc tttgctgtag tgaccatgac
    23461 cgtcactgca caaatgctta acggtcatca aagttgccac ggcgggcagc tattttcact
    23521 ggctgatact gcctttgcct acgcctgcaa tagccagggg ctggcagccg tcgcttctgc
    23581 ctgcacgatt gattttttgc gtccaggctt tgccggagac accttaactg ctactgcgca
    23641 ggtacgtcat cagggcaagc aaaccggtgt ttacgacatc gaaattgtta accaacaaca
    23701 aaaaacggtt gcgctgtttc gcggtaaatc tcaccgcatc ggcggcacca ttacaggaga
    23761 agcctgatgc gtgaagcctt tatctgtgac ggaattcgta cgccaattgg ccgctatggt
    23821 ggggcattat caggtgttcg ggctgacgat ctggctgcta tccctttgcg ggagctgctg
    23881 gtgcgaaacc cgcgtctcga tgcggagtgt atcgatgatg tgatcctcgg ctgtgctaat
    23941 caggcgggag aagacaaccg taacgtagcc cggatggcga cgttactggc ggggctgccg
    24001 cagagtgttt ccggcacaac cattaaccgc ttgtgtggtt ccgggctgga cgcactgggg
    24061 ttcgccgcac gggcgattaa agcgggcgat ggcgatttgc tgatcgctgg tggcgtggag
    24121 tcaatgtctc gggcaccgtt tgttatgggc aaggcaacca gtgcattttc tcgtcaggct
    24181 gagatgtttg ataccactat tggctggcga tttgtgaacc cgctcatggc tcaacaattt
    24241 ggaactgaca gcatgccgga aacggcagag aatgtagctg aactgttaaa aatatcgcga
    24301 gaagatcaag atagttttgc gctacgcagt cagcaacgta cggcaaaagc gcaatcctca
    24361 ggcattctgg ctgaggagat tgttccggtt gtgttgaaaa acaagaaagg cgttgtaaca
    24421 gaaatacaac atgatgagca tctgcgcccg gaaacgacgc tggaacagtt acgtgggtta
    24481 aaagcaccat ttcgtgccaa tggggtgatt accgcaggca atgcctccgg ggtgaatgac
    24541 ggagccgctg cgttgattat tgccagtgaa cagatggcag cagcgcaagg actgacaccg
    24601 cgggcgcgaa tcgtagccat ggcaaccgcc ggggtggaac cgcgcctgat ggggcttggt
    24661 ccggtgcctg caactcgccg ggtgctggaa cgcgcggggc tgagtattca cgatatggac
    24721 gtgattgaac tgaacgaagc gttcgcggcc caggcgttgg gtgtactacg cgaattgggg
    24781 ctgcctgatg atgccccaca tgttaacccc aacggaggcg ctatcgcctt aggccatccg
    24841 ttgggaatga gtggtgcccg cctggcactg gctgccagcc atgagctgca tcggcgtaac
    24901 ggtcgttacg cattgtgcac catgtgcatc ggtgtcggtc agggcatcgc catgattctg
    24961 gagcgtgttt gagcatatca acctgcgagt accctacaat gataaccaat acaaagcttg
    25021 acccgattga aaccgcgtct gttgatgagt tacaggcgtt gcaaacacaa cgtctgaaat
    25081 ggacgctcaa acacgcgtat gaaaatgtcc cgatgtatcg gcgcaaattt gacgcagcag
    25141 gcgtacatcc tgatgatttc agggaacttt cagatctgcg taaatttccc tgtaccacca
    25201 aacaggatct gcgcgacaac tatcccttcg acacctttgc cgtgccgatg gaacaagtgg
    25261 tgcgcattca tgcttcttcg ggaaccacag gtaaaccgac agttgtcggc tatacgcaaa
    25321 acgatattga taactgggcc aatattgtag cgcgttcctt gcgtgcggca ggtggcacgc
    25381 ccaaagacaa aattcatgtt gcctatggtt acggcctgtt tactggtggg ctgggcgcgc
    25441 actatggtgc cgaacgtctg ggcgctacgg tgatcccgat gtctggtggg cagacggaaa
    25501 aacaagcgca actgatccgc gattttcaac cagatatgat catggttacg ccatcttatt
    25561 gccttaacct gattgaagag ctggagcggc agttgggcgg tgatgccagc ggttgctcgc
    25621 tgcgggttgg agtgtttggt gctgagccgt ggacacaggc catgcgtaaa gagattgaac
    25681 ggcgtctggg gatcaccgca ctggatattt atggcctgtc agaagtgatg gggccggggg
    25741 tggcgatgga gtgtctggaa actaccgacg gcccaaccat ttgggaagat catttctatc
    25801 ctgaaattgt taatcctcat gacggcacac cgcttgccga tggtgaacat ggcgaactgt
    25861 tattcaccac gctgaccaaa gaagcattgc cggtcattcg ttaccgcacg cgtgatttaa
    25921 cccgactgtt accaggaacg gcgcggacta tgcgccgcat ggatcgcatc agcggacgca
    25981 gcgatgacat gttgatcatt cgcggtgtaa atgtcttccc gtcacaactg gaagaagaga
    26041 ttgtcaaatt cgaacattta tcgccccatt accaactgga ggtgaaccgc cgggggcatc
    26101 ttgattcact ttctgtgaaa gtggagttga aagaaagcag cctgacattg acgcatgagc
    26161 agcgttgcca ggtgtgccac cagctgcgcc atcggattaa gtcgatggtg gggatctcta
    26221 ccgatgtgat gatcgttaac tgtggcagta tcccgcgttc agaaggcaag gcgtgtcggg
    26281 tgtttgatct gcgcaatatt gttggtgcct gacgtgtcgt ctggccctgg tgaggtaaag
    26341 cgccagggcc agaagtcgat acgacctgtg ctatgattca taaatcacaa caataacaac
    26401 agactgaagc gaatgagtaa acttgatact tttatccaac atgctgtaaa cgctgttccg
    26461 gtcagtggca catctttgat ctcctctctg tatggtgatt cgctttccca tcgtggtggt
    26521 gaaatctggc ttggtagtct ggctgctttg ctggaagggc tgggatttgg tgagcgtttc
    26581 gtgcgcaccg ctttgtttcg tcttaataaa gaaggctggc tggatgtttc ccgcatcggg
    26641 cgacgcagtt tctatagcct cagtgataaa ggcttgcgcc tgacgcgacg ggcagaaagt
    26701 aaaatttatc gcgcagagca acctgcatgg gatggtaaat ggctcctgtt gctctcggaa
    26761 ggtttagata aatcaacgct ggctgatgtc aaaaagcagt tgatctggca aggttttggc
    26821 gcactggcac ccagcctgat ggcatcgccg tcgcaaaaac tggcggatgt acagacactt
    26881 ttgcatgaag cgggggtggc ggataacgtg atttgttttg aagcgcaaat accactggcg
    26941 ctttctcgtg cagcactgcg tgccagagtg gaagagtgct ggcatttaac tgaacaaaat
    27001 gccatgtacg aaacctttat tcagtcattc cgcccgctgg tgccgctgtt aaaagaggca
    27061 gcagacgagt taaccccgga gcgtgcattt catattcagc ttttactgat ccatttttat
    27121 cgccgtgtcg tccttaaaga cccattgttg ccagaggagt tgcttccggc gcactgggca
    27181 gggcatacgg cgcgtcagct gtgtatcaac atttatcagc gcgtagcgcc tgctgcttta
    27241 gcgttcgtta gtgaaaaagg tgaaacctcg gtcggtgaac tgcctgcgcc gggaagcctg
    27301 tattttcaac gttttggcgg tttgaatatt gaacaggagg cgatatgcca atttaccaga
    27361 tagatggtct gactccggtt gtgccagaag agagttttgt ccatccgaca gcggtattga
    27421 tcggcgatgt tattctaggc aagggcgttt acgttgggcc aaatgccagc ctgcgtggcg
    27481 attttggtcg tatcgtggtg aaagatggcg cgaacattca ggataattgc gttatgcacg
    27541 gttttcccga gcaggatact gtcgtggaag aagatggaca tattggtcat agcgctatcc
    27601 ttcatggttg cattatccgc cgcaatgcat tagtgggaat gaacgcggta gtgatggacg
    27661 gcgcggtgat tggcgagaac agcattgttg gcgcatccgc atttgtgaaa gccaaagcag
    27721 aaatgcctgc caattacctg attgtcggca gcccggcgaa agcgattcgt gaactcagtg
    27781 agcaggagct ggcatggaaa aagcagggta cgcatgagta tcaggtgctg gtgactcgtt
    27841 gtaagcagac gttgcatcaa gttgagccat tgcgggaagt tgaaccgaac aggaaacgtc
    27901 tggtatttga tgagaatctg cgaccgaaac agtaacgtcc agatactgaa cattctaatt
    27961 tttagcatgt gatacctaaa ccgcaacgct gatacaggtt gcggtttttt tattgccgga
    28021 tgcggcgctt tacgcgtttt gttttgtgtt tttcaggaca atagagcaac tcatccagta
    28081 atcttgttta cgccctcgca ttatttatct cttttcgttt ctatactgat ttttcttaat
    28141 ccgttttatt acagggcagg gtgcgatgag cagcaataca tttactctcg gtacaaaatc
    28201 cgttaaccgt cttggttatg gcgcgatgca actggcaggt cctggggttt ttggtccccc
    28261 aagagatcgc cacgtcgcta taactgtgct gcgcgaggcg ctggcattgg gcgtcaatca
    28321 cattgatacc agcgactttt atggtccgca cgtcaccaat cagattatcc gcgaagcgct
    28381 ttatccttac tctgacgacc tgacaattgt cactaaaatt ggtgcgcggc gtggagagga
    28441 cgcttcctgg ttgcccgcct tttctccggc agagttgcaa aaagcggtgc acgataatct
    28501 acgtaatctc ggcctggacg tactggatgt ggttaacctg cgcgttatga tgggagatgg
    28561 tcatggccca gcggaaggat cgattgaggc cagcctgacc gtgctggcag agatgcaaca
    28621 acaaggcctg gtaaaacata ttggcctgag caacgtcaca ccgacgcagg ttgcagaggc
    28681 gcgcaagatt gccgaaattg tctgtgtgca aaacgaatac aacatcgcgc accgtgctga
    28741 tgatgcaatg attgatgctt tggcccacga tggcattgcc tacgtgccgt tcttcccgct
    28801 cgggggcttt acaccgctgc aatcctctac gctgtcggat gttgctgcga gcctgggtgc
    28861 aacacccatg caggtggcgc tggcgtggct gttacaacgt tcaccgaata ttttgctgat
    28921 cccagggacg tcttctgttg cgcatttacg ggagaatatg gctgctgaaa aattgcatct
    28981 ttctgaggaa gtgttgtcta cgttggatgg tatttcgcga gaataacgaa tatacaaaag
    29041 ggaaagatgc atttcccttt tgtttctttt ttaatggcat ggagtgcata tgtttaagcc
    29101 caggatttgc agctggatag gtttacttcc cctgtttatg ctgagtcttc cagtacaggc
    29161 ggaacttcga tgtgttgcaa atgcagttga tattgaacca tttttttctg cagctaccgc
    29221 tgaagataaa caacaagttg aacaagctat caacagtagc gtgaatcttg tccccttcgg
    29281 tttatctgca tcggactgga aagtgcatcg tggcgattta gtggtagaag gtaatataga
    29341 gagtaatcaa aaattgattg ttcttggcaa tttgacagtc aaaggtaata tttccacttt
    29401 ctctctttct aatccatggg ttattctcgg taacgtgacg gcaacgaata tagttacgga
    29461 ttcaccactg ttaattaccg gttcgataaa tgcaagtgga ctggtattta tcgactcata
    29521 ttacgataat ccgtctacga ttaagggggt attaatgcgc gtgggatatt tatcaatgac
    29581 ataattgcac ctgttgttgc gtcttcgaca aatagtgaat tcatggtccg tgcgagtgac
    29641 aaaaatgaca ctgaaaatgt caaaaaagcg ctgatgataa taaatcctga tgcatattat
    29701 tggggtctaa taaatgatga agatgctctg aaagaaattt ttaagcgaag caatattcgc
    29761 atggcaggga atgtctgtaa tcagatgaaa aaagaagcgc tgtttcgccc taagccttct
    29821 cctgagttag tgcaggaatt gcaaatgctg gatgaaggca acgttgctgc atttgaagga
    29881 cgagatattg cgacatttga tcttgccata atgcgaactc tcccaaggct taaaggaatt
    29941 tcagctaacc tacgcaaaca acttattaat agcaatgatg aacaaacgat tgaaagtatg
    30001 gcgagatata tgcctgacaa tgagattctg gagttgaccg atcagcaatt gggttaccag
    30061 cctgttgttc tggggttgct cgaccgtgaa ccgctctctg tcgaaataat gacgcgaatg
    30121 agtcgtctac ctgatggtgt cggtccgttg aatcttgcgc tacgtgaaaa tctccctctg
    30181 gatatcgtaa tgactctggc gaaaagagat tgggatatga tcattcagga gctttataaa
    30241 gatgcgtggt tattgcctga atccattatt gatggctata tccgcagtga tgattcctct
    30301 attcgtcagg tcggtgctgg aggacaactc acctacaatc aggcaatgca gttggcgaac
    30361 gattcatcaa acaatgttgt cacaagctta acgttcaagc tggcagagat gaaacaccat
    30421 ggtcaattat tgcggatgac gccacaagag agtgacaaag ttgcagccta tttataccaa
    30481 aaattcgaga atgacgatga tctaatacgt gtgttatttt tagcattgcc agataactta
    30541 cagtttaatt ttgttaaaag gatggagaaa aaatcccctg cctacttttg ctgtcgggat
    30601 atgcaggtaa ttcactctga cgctgcttta caacggttat tgacacgttt caacgatcct
    30661 gaggggtgga gtaatctggc gaaaaatcag tatctgagca cgtcgatgaa acaaaaaatt
    30721 tggcaacgtg ctttatcgca tcggaaaaat aatccgaaag cagattcagc tgcgtatgaa
    30781 accagcgctg atatgatttt gtctgagctt atcagccacg gtgaagttga tgaccagatg
    30841 ctattaaatg ccaccgccct gatacgtttg gaagactggg actttttaga gagtgcatta
    30901 gttagttggg ataatttacc cgctgttgtc ctcaaggaat tacagcaaaa tacgccacgc
    30961 aatgatattt gggcgaagtt ttttctgagg caggaaaaca gctcccgtgc gcaggttgat
    31021 gaagcattac gcgtctatta tgcactcgac cccgatgcgt tagcacaact ggatgtactg
    31081 gcaaaacaac cggatcgtat atggtggagt acactggcga aaagcaatct cacatttttc
    31141 aagttcggcg cacttaacaa ccgccacaca ccgcctgcag tactggcggc agaaattgat
    31201 cccgagtggt ggattgtggc gatgaataat ccccgttttc cagttgatgt attaaaggcg
    31261 aggctgaaac gtgatccttt gctggcgtta gagcttgtta accctgaact ggatttagtc
    31321 cgccagctgg cgcttaacgg taagacgcgc gcaatacggg aacaagcgat gagaaaactt
    31381 gatgagttgt attgatccac aacgtaatat ttcttaaccc tttgattaat tggggataat
    31441 tattcctgac agtgagtccc caataccttg atatattctg aatttttaat gaagcggcgt
    31501 gttgcgatat ctccgtcagg ggaattgatg caccatagcg caaaccgaat tatcaaggat
    31561 tgataatgac gctctaccag ataaaaccgc tctttcagtc gctgttaagg ccgacgatgt
    31621 tttggcttta caagcaccac gttacagcga atcacatcac tcttgctgca ctggcgcttt
    31681 ctcttcttac cggattgctg ttggtgttgg tggcacaacc catcctcttt ttgctattgc
    31741 ccatcgtgct ttttatccgt atggcgctca atgcgctgga tggcatgttg gcgcgtgagt
    31801 gcaatcagca aacacgtctg ggggcgattt tgaatgaaac tggcgatgtt atttccgata
    31861 ttgcgctcta tttaccgttt ttatttttac cggaaagtaa cgcattactc gtaatactca
    31921 tgttattttg caccatattg actgagtttt gtggtttact cgcgcagaca attaacggta
    31981 ttcgcagtta tgccggtcca ttcggcaaaa gcgatcgtgc gttaatattt gggttgtggg
    32041 ggctggccgt ttccatttat ccacagtgga tgcaatggaa taatctttta tggagcattg
    32101 cttcaattct gcttctctgg actgcgatta atcgttgtcg gagtgtgctt tttatgagtg
    32161 ctgaaagata atgctggaaa aatctctggc aacacttttc gcgttgttaa ttttagcaac
    32221 gctgataaac cgttttctgc tatggcggtt accggagaga aaagggggtg aggttacatt
    32281 acgtattcgt acctggtggg gcatcgtcat ttgtttttca ctggtgattt caggtccacg
    32341 ctggatgacg ttgacgtttt ttgcgctgat aagttttctg gcattgaaag aatattgtac
    32401 gcttatatcc atacattttc cgcggtggtt atattgggtt attcctctta actatttgct
    32461 tatcggtttt aattgctttg agatgtttct gttatttata cctttgtctg ggtttctgat
    32521 atcagccacc tggcgagttt ttgtgggtga accctccggt tttctgcata ccgtgagcgc
    32581 tattttttgg ggctggataa tgaccgtttt cgccttgagt catgccgcct ggttattaat
    32641 gtttccatcc atgaatatcc agggcggggc gttactggtg ttatttcttt tggcattaac
    32701 cgagtcaaac gatattgcac agtatttatg gggaaaatcc tgcggcagaa gaaaagtggt
    32761 ccccaaagtc agcccgggaa aaacgctgga gggtctggtg gggggcgtca tcaccaccat
    32821 gattgcgtca ctgattattg gaccgttgct gacaccgcta aatacattac aggcattatt
    32881 agcgggtttg ttaattggta ttagtggttt ttgcggcgat gtcgtgatgt cagccatcaa
    32941 acgagatatt ggtgttaaag atagtggaaa actattacca ggacatggcg gactccttga
    33001 caggattgac tcattaattt tcaccgctcc ggtatttttt tattttattc gctacagctg
    33061 ttactgaagg aaaatagaga aaatggaaaa ttcacgcatc cctggggaac atttttttac
    33121 caccagtgat aatacagcgt tgttttatcg gcactggccc gctttacagc ccggggcgaa
    33181 aaaggtcatc gtcttatttc atcggggtca tgaacattct ggtcgtctac aacatctcgt
    33241 tgatgaactg gcgatgccag atactgcttt ttatgcatgg gatgcccggg ggcatggaaa
    33301 aacttcgggg ccgcgtggtt atagcccatc tcttgcgcgt tcagtgcagg atgtcgatga
    33361 atttgtccgt tttgctgcca gcgacagcca ggttggactg gaagaggtgg ttgtgatcgc
    33421 gcaaagcgtc ggcgcagtgc tggttgccac atgggttcat gattatgcgc ctgcaattcg
    33481 cgggctggtg ctggcttctc cggcctttaa ggttaaattg tatgtgccgc tggcacgtcc
    33541 tgcgctggcg ttatggcatc gtctgcgtgg tctgtttttt attaattcct atgtgaaagg
    33601 acgctatttg acccacgatc ggcaacgggt ggcgagtttc aataatgatc cgctgatcac
    33661 acgggcgatt gccgtcaata tcttgctcga tctctataaa acgtctgaac gtattgttag
    33721 cgatgcggcg gcgattacgc tccccacgca acttctgata tcaggcgatg actatgtggt
    33781 gcatcgccaa ccgcagatcg atttttatca gcgtttacgt agccctctca aagagctgca
    33841 tctgctgcca ggcttttatc acgacacgtt gggtgaagag aacagggcgc tggcatttga
    33901 aaaaatgcaa agctttatta gtcatttata tgctaacaaa tcgcaaaaat ttgattatca
    33961 gcatgaagac tgcacaggac catcagcgga tcgatggcgg ctactttctg gtggacccgt
    34021 gccattatcg ccggttgatt tggcgtatcg ctttatgcgt atggcgatga aattgttcgg
    34081 ggcgcactct gcgggcctgc atctcggaat gagcaccggc tttgattcag gcagttcgct
    34141 ggattatgtc tatcaaaatc aaccacaagg tagtaacgca ttcgggcgtt tagtcgacaa
    34201 aatctacctg aacagtgttg gctggcgcgg tattcgccag cgcaaaaccc atttacaaat
    34261 gctgattaaa caagccgttg ccgatctcca cgccaaaggt ttagccatcc gcgtggttga
    34321 cattgccgca gggcatgggc gctatgtact ggatgcgctg gagaatgaac ctgccgtatg
    34381 cgatattttg ttacgtgatt acagtgagtt aaatgttgca caggggcaag agatgattgc
    34441 ccaacgggga atgtctgggc aggtgcgttt tgaacagggc gatgcgttta acccggagga
    34501 actcagcgcg ttaactccgc ggcctacgct ggcgattgtc tctggcctgt atgagctttt
    34561 tcccgaaaat gagcaggtaa aaaactccct cgcaggtctt gccaatgcca tcgaaccggg
    34621 tggcattctc atctacaccg ggcagccgtg gcacccacaa ctggagctga ttgccggggt
    34681 gttaaccagt cataaagatg gtaaaccgtg ggtgatgcgc gtgcgttcgc aaggggagat
    34741 ggattcactc gtgcgtgatg ccggatttga taaatgcaca caacggattg atgagtgggg
    34801 tatttttacg gtttcgatgg cggtgcgtcg tgataactga acgtcggaac gtattgctac
    34861 aaggcgctgg ctggttattg ttgctggccc cgtttttctt cttcacctat ggatctctta
    34921 atcagttcac cgcggttcag gaccttaaca gccatgatat ccccagtcag gtattcggtt
    34981 gggaaacggc gatccctttt cttccctgga ctattgttcc ttactggagt ctggatcttt
    35041 tatatggatt ttcgctgttc gtttgtagca cgacattcga acagcgccga cttgtccacc
    35101 ggcttattct ggcaacggta atggcctgct gcggtttttt gctctatccg ctgaagttta
    35161 gttttatccg tcctgaagtg agtggggtga cgggatggct attttcgcaa cttgaactgt
    35221 ttgatctgcc ttataaccag tctccttcgc tgcatattat tctctgctgg ctactttggc
    35281 gtcactttcg tcagcatctg gctgagaggt ggcgtaaagt ctgtggcgga tggtttttac
    35341 tcatcgctat ttctactctg acgacctggc agcatcattt tattgatgtc atcacagggc
    35401 tggcggtagg tatgttgatt gactggatgg tgcccgtcga tcgtcgttgg aattatcaga
    35461 aacctgatca acgtcgaatc aaaatagcac tgccatatgt cgtaggcgcg ggctcgtgca
    35521 ttgtgttgat ggagctaatg gtgatgattc agttatggtg gtcagtctgg ttatgttggc
    35581 cagtattatc gctactcatt attggccgtg ggtacggtgg gcttggcgcg ataacaacag
    35641 ggaaagatag tcaggggaaa ctcccgcccg ccgtttactg gctgacattg ccctgccgca
    35701 tcgggatgtg gctgtctatg cgttggtttt gtcgtcgcct ggagccggtg agcaaaatga
    35761 ctgctggtgt ttatttaggg gcgtttccac gacatattcc ggcacagaat gcggttctgg
    35821 acgtcacctt tgaattccct cgcggacgag cgacaaaaga tcgactctat ttctgtgtac
    35881 cgatgctgga tctggtggtt ccggaagagg gggagctccg acaggccgtg gcgatgctgg
    35941 aaacattacg cgaagagcaa ggcagcgttc tggtccattg cgcgttggga ttatcgcgca
    36001 gtgcgctggt agtggcggca tggttgttat gttacggaca ctgtaaaacc gttgatgaag
    36061 cgattagtta tattcgagcc agacgttcgc atattgtgct taaggaagat cacaaagcga
    36121 tgctgaaatt atgggaaaac aggtaagtgg attgagatgt ggactgaact acagtccaca
    36181 tcaagatcgt gtccggttat gcagcaacaa tgctgtcgat ggccgctttc gcgtcagact
    36241 gcgctttcgc tgccatttcc ggaccgtatg cgatcccttc ggcgaagaca aatttcacat
    36301 cggtaatgcc gataaagccg aggaacgtgg acagatacgg cgtcaccagg tccgttggtc
    36361 catctttgtg gatcccaccg cggctggtaa taacgatggc ttttttaccc gttaccagac
    36421 cttccggacc gttctcggta tagcggaaag taacgcctgc gcgtgcaacc aggtcaaaat
    36481 agtttttcaa ctgagttgag atgttgaagt tatacatcgg tgccgcaata acgataacgt
    36541 cgtgggcttt cagctcggca atcagctcat cggaaagcgc cagagcttcc tgctgacgcg
    36601 gagtcagcgg cgcatcgctc ggacgcagtg caccaaccag ttcgccatcc agtaccggaa
    36661 tcggatttgc agccaggtcg cgaacggtga tttcatcagc ggagtgcttt tcgcgccatt
    36721 gttcaacaaa ataatcggac aactgattag actgagagta ccctgccagg atgctggatt
    36781 taagaactaa taccttgctc atggtgtttc cttatagatg tttgaatggg cgatgccccg
    36841 ttgcttgctg acactttatt cacaatcctg ccacagagat agcgcaataa atcgaagcct
    36901 atgttcgaat ttattgaaca acgcatagaa agccgcgatg tggtactcta tatctatcat
    36961 ttaaaagaaa attaatcagg cagactactg cccactaacg ttatgacaga acaacaaaaa
    37021 ttgaccttta cggccttgca gcagcggctg gattcgctga tgccgcgcga cagactgcgt
    37081 ttttctcggc gtctgcacgg tgttaagaag gttaaaaatc ctgatgcaca acaggccatt
    37141 ttccaggaga tggcgaaaga gattgaccag gcggcaggga aagtcctgct gcgtgaagcg
    37201 gcacgaccgg aaattactta tcctgacaat ttaccggtta gtcagaaaaa acaggacatt
    37261 ctcgaagcga ttcgtgatca ccaggtggtg atcgtcgccg gggaaacggg ttctggtaaa
    37321 acgactcagt taccgaaaat ctgtatggag ctggggcgcg gggttaaagg gctgatcggc
    37381 catacccagc cgcgtcgcct ggcggcaaga acggtggcga accgtattgc ggaagagctg
    37441 aaaacggagc cgggcggttg catcggttac aaagtgcgtt tcagcgatca cgttagtgat
    37501 aacacgatgg tcaagctgat gaccgacggt atcctgctgg cggagatcca gcaagaccgc
    37561 ctgctgatgc agtacgacac catcattatt gacgaagcac acgaacgcag cctgaatatc
    37621 gattttctgc tcggctattt gaaagagttg ctgccgcggc gtcctgacct aaaaatcatt
    37681 atcacttccg cgactatcga cccggaacgc ttttcgcgcc actttaataa tgcgccgatt
    37741 atcgaagtct ccggtcggac ctatccggtg gaagtgcgct atcgaccgat tgttgaagaa
    37801 gccgacgaca ccgagcgcga tcagttgcag gcgatttttg acgccgtaga cgaactgagt
    37861 caggaaagcc ctggcgacat tctgatcttt atgagtggtg agcgggaaat tcgcgatacc
    37921 gccgatgcgc tgaacaagct aaatctgcgt cataccgaaa tcttgccgct ttatgcgcgg
    37981 ctttcgaaca gcgaacagaa ccgcgtgttc cagtcgcaca gcggacggcg cattgtgctg
    38041 gcgaccaacg tcgcggaaac ctcgctgacc gtaccgggga ttaaatacgt tatcgacccc
    38101 ggtacagcac gtatcagccg ctacagctat cgcaccaaag tgcagcgttt gccgattgaa
    38161 cccatttcgc aggcgtctgc caatcagcgt aaaggccgct gtgggcgtgt gtccgaaggg
    38221 atctgtattc gtctctattc cgaagacgat ttcctttcgc gcccggagtt taccgatccg
    38281 gagattctgc gtaccaacct ggcctcggtt attttgcaga tgaccgcgct ggggctgggc
    38341 gatatcgctg cgttcccgtt tgtcgaagca ccggataaac gcaatatcca ggatggcgtg
    38401 cgtctgctcg aagaactggg cgcgatcacc acggatgaac aggccagcgc ctataaactg
    38461 acgccgctcg gtcgccagct ctcgcagttg cctgtcgatc cacgtctggc gcgtatggtg
    38521 ctggaagcgc aaaaacatgg ctgcgtgcgt gaggcgatga ttatcacgtc cgcgctttcc
    38581 attcaggatc cgcgcgagcg tccgatggat aaacagcagg catcggacga aaaacatcgt
    38641 cgcttccacg acaaagagtc tgacttcctc gcgtttgtga atctgtggaa ttatcttggc
    38701 gagcagcaaa aggcgctttc ttccaacgct ttccgtcgcc tgtgtcgtac cgattatctc
    38761 aactatctgc gcgtgcgcga atggcaggat atctacaccc agttgcgcca ggtggtgaaa
    38821 gaacttggca ttccggttaa cagcgaaccg gcggagtatc gcgaaattca cattgcgttg
    38881 ctgacgggtt tactttccca tatcggcatg aaagatgccg ataaacaaga atataccggc
    38941 gcacgtaacg cgcgtttctc catctttccc ggttctggtt tattcaaaaa accgccgaaa
    39001 tgggtaatgg tggcggaact ggtagaaacc agccgcctgt gggggcgcat tgctgcgcgt
    39061 atcgacccgg aatgggtgga gcctgtcgct cagcatttga ttaaacgcac ctacagcgaa
    39121 cctcactggg aacgggcgca gggcgcggtg atggcaacgg aaaaagtcac tgtttatggt
    39181 ttgccgattg ttgccgcgcg caaggtcaac tacagccaga tcgatccggc gttatgccgt
    39241 gaactcttta ttcgccatgc gctggtggaa ggtgactggc agacgcgtca cgcattcttc
    39301 cgtgaaaacc tgaaactgcg ggccgaagtg gaagagctgg aacacaaatc acgtcgccgc
    39361 gatattctgg ttgatgacga aacgttgttt gagttctacg accagcgcat cagccacgat
    39421 gtgatctctg cacgccactt cgacagctgg tggaaaaaag tcagccgcga aacccctgat
    39481 ttgctcaact ttgaaaaaag catgttgatc aaagagggcg cagaaaaaat cagcaagctg
    39541 gattacccga acttctggca tcagggcaat ctcaagctgc gtttgagcta tcagtttgag
    39601 cccggcgcgg atgctgacgg tgtgaccgta catattccgc tgccgttact taaccaggtt
    39661 gaggaaagcg ggtttgaatg gcagatcccc ggtctgcgcc gcgaactggt gattgctctg
    39721 attaaatcgt tgccgaaacc ggtacgccgt aattttgtac ccgcaccaaa ctacgccgaa
    39781 gcgtttttag gccgcgtcac accgctggag ttaccgttgc tcgacagcct tgagcgcgag
    39841 ttacggcgga tgaccggtgt taccgttgac cgcgaagact ggcactggga tcaggtgccc
    39901 gatcacctga aaatcacctt ccgcgtggtg gacgacaaaa ataagaagct aaaagaaggg
    39961 cgctcattac aggatctgaa agatgcgctg aaaggcaaag tgcaggaaac gctgtccgcg
    40021 gtggcggatg acggtatcga gcagagcggg ctgcatatct ggagctttgg gcaactgccg
    40081 gaaagctacg aacagaagcg cggcaactat aaagtgaagg cgtggccggc gctggtggat
    40141 gaacgtgaca gtgtggcgat caaactgttt gataacccgc tggagcaaaa acaggcaatg
    40201 tggaacggtc ttcgccgtct actgctgcta aatattccct cgccgatcaa gtatttacat
    40261 gagaagttac caaacaaagc caagcttgga ctgtacttta acccgtatgg caaagtgctg
    40321 gagctgatcg acgactgtat ctcctgcggt gtggatcaac tgatcgacgc caatggtggc
    40381 ccggtctgga cggaagaagg ctttgctgcg ctgcatgaga aagtgcgtgc cgaactgaac
    40441 gacacggtgg tagatattgc gaagcaggtc gagcaaattc ttacggcagt gttcaatatc
    40501 aacaaacgtc tgaaagggcg ggtggatatg accatggcac tggggctttc tgacattaaa
    40561 gcgcagatgg gcgggttggt atatcgcgga tttgtcactg gtaacggctt caaacggctg
    40621 ggcgacacgc tgcgatattt gcaggcgatt gaaaaacggc tggaaaaact ggcggttgat
    40681 ccacatcgcg accgtgctca gatgctgaaa gtcgaaaacg tccagcaggc gtggcagcaa
    40741 tggatcaaca aactgccgcc tgcacgtcgt gaggatgaag acgtgaaaga gatccgttgg
    40801 atgatagaag agttgcgcgt tagttacttc gctcaacaac ttggtacgcc ttatccgatt
    40861 tcagataagc gtattttgca ggcgatggag cagattagcg gttaaccctg ctatttgcct
    40921 gataaagaaa aaacccggta agcatttagc gccgggtttt ttattaattc taaaacggta
    40981 agggtaaaaa ttcaggaatt cagaaaaata caattctctg ctgcaagatg aataatgttt
    41041 atctacagca tttccttaaa agatatgtca ggcttgcgga gtggcggtta aggacatacg
    41101 acttcctcct ttcagagtgc tccgcttctc actattatct cacgcagtat tcttaaggga
    41161 acgataagga ggaaccatga acattacccc gtttccgacg ctttcgccgg caactataga
    41221 tgccataaat gttatcggac agtggctggc gcaggatgat ttctccggtg aggtgccgta
    41281 tcaggccgat tgcgtgatcc ttgcaggcaa tgcggttatg ccgactatcg acgcggcatg
    41341 taagattgct cgcgatcagc aaattccttt actgattagt ggtggtatcg gtcactcgac
    41401 aacttttttg tatagcgcca tcgcacagca tccgcactac aacactatcc gcaccactgg
    41461 cagagcagaa gcgaccatcc tggcggatat cgctcatcag ttctggcaca ttccgcatga
    41521 aaaaatctgg attgaagacc agtcaacaaa ctgcggtgaa aacgcacgct ttagcatcgc
    41581 gctattgaaa caggccgtag aacgagttca tacggctatc gttgttcagg accccaccat
    41641 gcagcggcgc acgatggcga cgttccgccg tatgactggg gacaatcccg atgcaccacg
    41701 ctggttaagt tatcccggat tcgttcctca gttaggaaat aacgcagaca gtgtaatctt
    41761 tattaatcag ttacaaggat tatggccggt tgagcgttat ctctcactac tcactggcga
    41821 gctgccgcgt ttacgcgatg atagcgatgg ctacggtccc cgcgggcgag attttatcgt
    41881 tcacgttgat tttccggcag aagtcatcca tgcatggcaa acgctgaaac atgatgcggt
    41941 gctcatcgag gcgatggaaa gtcgctcgtt acgttaaaaa ttgcccgttt gtgaaccact
    42001 tgtttgcaaa cgggcatgac tcctgacttt tatttctgcc ttttattcct tttacacttg
    42061 tttttatgaa gcccttcaca gaattgtcct ttcacgatgc cgtctctctg atgattgatg
    42121 ttaattaaca atgcattcac agaaaacaaa catataaatc acaggagtcg cccatgtcag
    42181 tacccgttca acatcctatg tatatcgatg gacagtttgt tacctggcgt ggagacgcat
    42241 ggattgatgt ggtaaaccct gctacagagg ctgtcatttc ccgcataccc gatggtcagg
    42301 ccgaggatgc ccgtaaggca atcgatgcag cagaacgtgc acaaccagaa tgggaagcgt
    42361 tgcctgctat tgaacgcgcc agttggttgc gcaaaatctc cgccgggatc cgcgaacgcg
    42421 ccagtgaaat cagtgcgctg attgttgaag aagggggcaa gatccagcag ctggctgaag
    42481 tcgaagtggc ttttactgcc gactatatcg attacatggc ggagtgggca cggcgttacg
    42541 agggcgagat tattcaaagc gatcgtccag gagaaaatat tcttttgttt aaacgtgcgc
    42601 ttggtgtgac taccggcatt ctgccgtgga acttcccgtt cttcctcatt gcccgcaaaa
    42661 tggctcccgc tcttttgacc ggtaatacca tcgtcattaa acctagtgaa tttacgccaa
    42721 ccaatgcgat tgcattcgcc aaaatcgtcg atgaaatagg ccttccgcgc ggcgtgttta
    42781 accttgtact ggggcgtggt gaaaccgttg ggcaagaact ggcgggtaac ccaaaggtcg
    42841 caatggtcag tatgacaggc agcgtctctg caggtgagaa gatcatggcg actgcggcga
    42901 aaaacatcac caaagtgtgt ctggaattgg ggggtaaagc accagctatc gtaatggacg
    42961 atgccgatct tgaactggca gtcaaagcca tcgttgattc acgcgtcatt aatagtgggc
    43021 aagtgtgtaa ctgtgcagaa cgtatttatg tacagaaagg catttatgat cagttcgtca
    43081 atcggctggg tgaagcgatg caggcggttc aatttggtaa ccccgctgaa cgcaacgaca
    43141 ttgcgatggg gccgttgatt aacgccgcgg cgctggaaag ggttgagcaa aaagtggcgc
    43201 gcgcagtaga agaaggggcg agagtggcgt tgggtggcaa agcggtagag gggaaaggat
    43261 attattatcc gccgacattg ctgctggatg ttcgccagga aatgtcgatt atgcatgagg
    43321 aaacctttgg cccggttctg ccggtggtcg catttgacac gctggaagag gctatctcaa
    43381 tggctaatga cagtgattac ggcctgacct catcaatcta tacccaaaat ctgaacgtcg
    43441 cgatgaaagc cattaaaggg ctgaagtttg gtgaaactta catcaaccgt gaaaacttcg
    43501 aagctatgca aggcttccac gccggatggc gtaaatccgg tattggcggc gcagatggta
    43561 aacatggcct gcatgaatat ctgcagaccc aggtggttta tttacagtcg taatgagtaa
    43621 aagaggcgga ggttttttcc tccgcctgtg cgcgtcagag tttagcgaat ttttcgaggg
    43681 tgcgaataag ctgcgtgacg aagccatatt cgttatcgta ccaggcgacc gttttcacca
    43741 gttgtaaatc gcccacggcg gtaatttccg tttgcgtggc atcaaacacc gaaccgaaat
    43801 ggctgccaat gatatcggaa gagactattt cttcatcggt ataaccaaat gactcgttat
    43861 tggtggttgc ttgtttaagt gcgttattca cctcttcggc agtcactttt tttccgagaa
    43921 tcgataccag ttcagtgacc gaacctgttt tcaccggcac gcgttgcgca tgacctttca
    43981 gtttgccgct cagttccggg atcaccagac caatggcttt tgccgccccc gtagtgtggg
    44041 gaatgatatt ttctgccgct gcgcgtgaag cacgtaaatc tttaccacgt gggccatcca
    44101 ccagtgactg ggtgccagta taggcatgaa tggtcgtcat cgtgccgact tctatcccga
    44161 aactgtcatg caaggctttg gccatcggcg caagacagtt agttgtgcat gacgccacgg
    44221 aaacaatggt gtcgttgcca tccagagtgt cgtcattgac gttataaacg atagttttca
    44281 tttcaccggc aggggcggaa atcaacacct tcttcgcacc agcatcaaga tgcgcctgcg
    44341 atttctcggc ggaggtataa aagccagtac attcgacaat gatttctgca cctttcgctt
    44401 tccacggaat atttttagcc tctttttcgg cgtaaaccgc gatacttttc ccatcaacga
    44461 taagtgaatc ttccgtaaaa tcaacgctcc aggggaatgg tccgtagttt gaatcatgtt
    44521 tcagcaggta ggcgagaatt tttggggaag tgagatcatt aatagcgaca acgtctatgt
    44581 tgcttttgac ttcaagtaat cgacgcaaca ccagtcgacc gatacgacca aaaccgttaa
    44641 taccaacttt actcatggtt ttctcctgtc aggaacattc ggatgaaaat tgatcctttc
    44701 caggcttaga ccaggattgt gggatgggca atctccattc ttacagtgaa acgtaacgta
    44761 ctgaaaacgg gtgaacaata tttaatgaaa ttttgagaaa agcccgttat gttaacggaa
    44821 aattatgtta aagcaggaaa tgttatggaa aataaatact caaggttaca aatcagcatt
    44881 cactggctgg tctttttgct ggttatcgca gcgtattgcg caatggagtt tcgtggtttc
    44941 ttcccacgta gcgatcggcc actcatcaac atggttcatg tttcctgtgg tatctcaatt
    45001 ctcgtgctga tggtggttcg tcttttgtta agactgaaat acccaacccc gccgattata
    45061 cctaagccaa aaccgatgat gacgggactg gcgcatttgg gacatttggt gatttatctc
    45121 ctgtttattg cgctgccagt gattggtttg gtgatgatgt ataaccgggg caacccgtgg
    45181 tttgcgtttg gtttgacgat gccttacgct tcagaggcca atttcgaacg ggttgatagc
    45241 ttaaagtcgt ggcatgagac gctggcgaat ctgggatatt ttgtgatcgg gttgcacgct
    45301 gcggctgcac tggcacacca ctatttctgg aaggacaaca cacttctacg catgatgccg
    45361 cgtaaacgtt cctgaaggat atttcaagaa aacgcctgta ctaaaaccga cccgtggtac
    45421 aggcgaagaa tacgggtcta catcggaagc gcctattata tttatttgta tgacaaataa
    45481 aaccataatc cttgcccata cgtccatctg gcttattttt aatcaattca cccgatcttt
    45541 gatctcatca acggtatcaa aataaaccag cgtataacgt tcaaatcgaa cataagattc
    45601 gataaaccat ggaggttata tgaaaaaact ggcacttatt ttgtttatgg gaacgcttgt
    45661 ttccttttat gccgatgccg ggcgcaaacc ctgttctggt tcgaaagggg ggatctcaca
    45721 ctgtacggca ggcggcaaat ttgtctgtaa tgatggttct attagtgcct cgaaaaaaac
    45781 atgcactaac tgaagtgtaa aaggggtgcc atgagaaaat gaatctgcta gtcagatgcg
    45841 cggggaaaat ccccgcgctt gcccttacct ggacgtgcag gccatgagcg cagcaacctc
    45901 cttatcaccg tcccggaacc gcagttcgta gagcgtttgt cgggtcagga gtgtgaatgt
    45961 cagaatcgta atgcagataa tgagcagaca caccaccaga gggttgtgct tcatagcctt
    46021 tctccttgcc ggatggcggg taagaggcta agatctgaat tgctaggttc attcgttggc
    46081 ctcggttgat agaaatatcg gtcggggcct tcgtctttct gattcccggt tagcctgaaa
    46141 acagaaagtc tcaggcaccc gcaggcatcc tatgaggttt ccttagggac gaaaataatc
    46201 acttcacgaa attgcgtgct gttttccaga atttttcgtc attcgggtta gccagtttag
    46261 ccattcgtta ctctcttcat tccaatagca ttaattttct ctgcaataat tgttgtaaaa
    46321 atgtgacgca aagaggtttt tggtcataag taattaccgt caagtgccga tgactttcta
    46381 tcaggagtaa acctggacga gagacaacgg taatgaatac aactccctca cagcgattag
    46441 gttttttgca tcacatcaga ctggttccgt tatttgcctg cattcttggc ggtatcttag
    46501 ttctattcgc attaagttct gctctggctg gctatttcct ctggcaggcc gatcgcgatc
    46561 agcgtgatgt tactgcggag attgagattc ggaccgggtt agcgaacagt tcagattttt
    46621 tgcgttcagc ccggatcaat atgattcagg ccggggctgc gagtcgtatt gcggaaatgg
    46681 aagcaatgaa gcgaaatatt gcgcaagccg aatcggagat taaacagtcg cagcaaggtt
    46741 atcgtgctta tcagaatcgg ccggtgaaaa cacctgctga tgaagccctc gacactgaat
    46801 taaatcaacg ctttcaggct tatatcacgg gtatgcaacc tatgttgaaa tatgccaaaa
    46861 atggcatgtt tgaagcgatt attaatcatg aaagtgagca gatccgaccg ctggataatg
    46921 cttataccga tattttgaac aaagccgtta agatacgtag caccagagcc aaccaactgg
    46981 cggaactggc ccatcagcgc acccgcctgg gtgggatgtt catgattggc gcgtttgtgc
    47041 ttgccctggt catgacgctg ataacattta tggtgatacg tcggatcgtc attcgtccac
    47101 tgcaacatgc cgcacaacgg attgaaaaaa tcgctagtgg cgatctgacg atgaacgatg
    47161 aaccggcggg tcgtaatgaa atcggtcgct taaatcgtca tttacagcaa atgcagcatt
    47221 cactggggat gacagtaggg actgttcgac agggtgcgga agagatttat cgtggcacca
    47281 gcgaaatttc agctggcaat gcggacctgt catctcgcac cgaagaacaa gcggcggcta
    47341 tcgaacaaac tgccgctagc atggagcaac tcactgcgac ggtgaaacag aatgcggata
    47401 acgcgcatca tgccagcaaa ctggcgcaag aggcttctat taaagccagc gatggcgggc
    47461 agacggtttc cggtgtagta aaaacgatgg gcgctatctc tacaagttcg aagaaaattt
    47521 ccgagatcac cgccgtcatc aacagtattg ctttccagac gaatattctg gcactgaatg
    47581 ctgccgttga agccgcgcga gcgggtgagc aaggccgtgg atttgccgtt gtcgccagcg
    47641 aagtacggac actcgcaagc cgcagcgccc aagcggcgaa agagattgaa ggcttgatca
    47701 gtgaatcagt caggttaatt gacctggggt cggatgaggt ggcaacggca gggaaaacca
    47761 tgagcactat tgttgatgcc gtcgcgagtg tcacacatat catgcaggaa atcgccgccg
    47821 cctcggatga acaaagtaga ggcataacgc aggttagcca ggcgatttct gaaatggata
    47881 aggtgacgca acagaatgct tctctggtag aagaggcctc agcggcggcg gtgtcccttg
    47941 aagaacaggc ggcacgatta actgaggcgg tggatgtatt ccgtctgcac aaacattctg
    48001 tgtcggcaga acctcgcgga gcgggtgaac cagttagttt cgctacggtg tgaaaatgtt
    48061 caaggaggga tcgacagatc ccttcacctt tcagaacggc attgattttc gaatagcgtt
    48121 aatcatcaac tggcaaccag aagagaacgt cgcatctacg cgggtcagta ttccaatcgg
    48181 ttcgcctgca ccatgtcccg gaacaggcag ggccaccagc gtggcatgac gcaggtcgtc
    48241 ttttacagcg ccagaaggga caaaccacac gtaatcgtat tcaaccgtaa gttgacgaga
    48301 tagcgaagca gacagcgttt cgatacaacc cgaaggaatt ttacagccct ggctctgcac
    48361 taatgcatct gaatgctggc gtggcgcagt gccttctggt gatacaacga ccggccattc
    48421 cagcacccgg cttagcgtta cgttctcctg aagtagcggg tgattagggc ggacaaccag
    48481 cttcaacgat tcaagaaaca gcagttcgta attaagcccg gtcatcagtt caggatctga
    48541 catccgacca atgccgatat cgatttcccc ggtttttaaa cccgccagaa tcatagggtt
    48601 actcattgtc gcaacttgca aggtcgtctc tttttgttgc tgatgaaact gacctataac
    48661 cgaaggtaat atccccagtg ccgcagtagg tagtgcacca accctgacga catcattatt
    48721 aagaccttct ttacgatgaa gcgactgtcc ggcagtgttg atggcgtcaa gaactctgac
    48781 tgcatgcgtt aaaaattgtt cgccgggtaa ggtaagttgc gccccctgac gaccacgctc
    48841 aaacaagcga gcgccagtca gctgctccag ttcattcaat gtcttagaga gcgcaggttg
    48901 actcaaatta agggtttcag ccgcgcgccc caaagttcct tgttgtgcga cagctacgaa
    48961 tgtatgaagg tggcgcaaac ggatgcgctg actaaacaga ctattttttt ccataagcga
    49021 tgttaaaaac gaagcggtgt cgctgacaag tgaagttgtt tgattatgat aacttgattg
    49081 caaaatatta ttaacaatta aagcaattat gttacagcaa aatggataat attgatgttt
    49141 tcgcggcgag atcacagttt gtaaattctt cccgcaagag tgaatgcggt tacctacact
    49201 ccagattact gaccactgga ggcagacact atggcgaaca gcatcacggc ggatgagatt
    49261 cgggaacagt tttcgcaggc aatgtcagcc atgtaccagc aagaagttcc gcaatatggc
    49321 acgctgctgg aactggtagc tgatgtgaat ctggctgtgc tggaaaacaa tcctcaactg
    49381 cacgaaaaaa tggtaaatgc agacgagctg gcgcgactga atgttgaacg tcatggggcg
    49441 attcgcgttg ggactgcaca agagcttgct actcttcggc ggatgtttgc cattatgggg
    49501 atgtacccgg tgagctatta cgatctctcg caggcagggg tgccggtaca ttcgacagca
    49561 tttcggccca ttgatgatgc ttctctggcg cgtaatccct tccgcgtttt tacctcctta
    49621 ctccgccttg agcttatcga gaacgaaatt ttgcgccaga aagcggcgga gattctacgt
    49681 cagcgcgata tcttcacccc acgttgtcga caactgttag aggaatatga gcagcagggc
    49741 ggttttaacg aaacacaggc acaggagttt gtgcaggaag ccctggaaac gtttcgctgg
    49801 caccagtcag caacggtaga tgaagaaacc tatcgcgcct tgcacaacga acatcggttg
    49861 attgctgatg tggtctgttt tcctggatgc catatcaacc acctgacacc acgtacgctg
    49921 gatattgacc gggtgcagtc gatgatgcct gaatgcggaa ttgaacccaa aattctcatc
    49981 gaggggccgc cgcgccgcga ggtaccgatt ttactacgcc agaccagctt taaagcactg
    50041 gaagagacgg tgttgtttgc ggggcagaaa cagggcacgc ataccgcgcg ctttggtgaa
    50101 attgagcagc gtggcgtggc attaacgccg aaagggcgac aactgtatga tgatcttctg
    50161 cgtaacgctg gaaccgggca ggataatctc actcaccaaa tgcatttaca ggaaaccttc
    50221 cgcacttttc ctgacagtga gtttttaatg cgtcagcaag ggctggcatg gttccggtac
    50281 cgtctgacgc cttcaggtga ggcgcatcgt caggcgattc atcccggaga cgatccacag
    50341 cccttaattg aacgtggttg ggtcgcggcg caacccatta cctatgaaga tttcttgccc
    50401 gttagcgcgg cggggatctt ccagtcaaat ctgggtaatg aaacgcagac acgcagtcac
    50461 ggtaatgcca gtcgcgaagc atttgagcag gcgttgggtt gtccggtttt ggatgagttc
    50521 cagctttacc aggaagcgga agaacgcagt aaacgtcgct gtggtttgct ttaaattctg
    50581 accatccgcc tttgcaaaaa tttgcctgat tttacaaacg aatcaggctc atcccatcga
    50641 cataaaaaaa atgccgattt atgcatattc tctcagttca acaattggat tattaataaa
    50701 tattgtctag agtgagcggt cataaataag cactttcttg ccgctgaaaa cgaccagcgc
    50761 gggaccattc acaacaccag aaggactcac tttcaggtat ggatcgtaga cgatttatta
    50821 aaggttcaat ggctatggcc gccgtgtgcg gtaccagcgg cattgcttct cttttttctc
    50881 aggcggcatt cgcggcagat tctgatattg ccgacgggca aacccagcgt tttgacttct
    50941 ccattctaca gtcaatggcg cacgacttag cgcaaacagc gtggcgtggt gcgcctcgtc
    51001 cgttacctga cacgctggcg acaatgacgc cgcaggctta taacagtatt caatacgacg
    51061 ccgaaaaatc gctctggcat aacgttgaga accgtcaact ggacgctcag ttcttccata
    51121 tgggaatggg attccgtcgc cgcgttcgta tgttttctgt agatccagca acacatctgg
    51181 cgcgtgaaat tcactttcgc ccggagttgt tcaaatacaa cgatgcgggt gttgatacaa
    51241 aacaattaga agggcaaagc gatctcggct ttgccggttt tcgcgtgttt aaagcccccg
    51301 aactggcgcg ccgtgatgta gtatcatttc tcggcgcgag ttatttccgc gccgttgatg
    51361 atacatatca atacggtttg tcggcccgcg gcctggcgat cgacacttac accgacagta
    51421 aagaagagtt ccccgacttt accgccttct ggtttgatac ggtaaaaccg ggggcaacta
    51481 cctttaccgt ttatgcgttg ctcgatagcg ccagcattac tggtgcctat aagttcacta
    51541 tccattgtga gaaaagtcag gtgattatgg atgtggaaaa tcacctgtat gcgcgcaaag
    51601 acattaaaca gctgggcatt gcgccgatga ccagtatgtt cagctgcggt actaatgaac
    51661 gtcggatgtg cgacaccatt catccgcaaa ttcatgactc tgatcgtctg tccatgtggc
    51721 ggggcaacgg cgagtggatt tgccgtccgc tgaataatcc gcaaaaattg cagttcaatg
    51781 cttacaccga caacaacccg aaagggtttg gtttattgca actggatcgt gacttctccc
    51841 attatcagga cattatgggc tggtataaca aacgcccaag tctgtgggtg gaaccgcgta
    51901 acaagtgggg taagggcacc atcggcctga tggaaatccc aacaacgggc gaaacgctgg
    51961 ataacattgt ctgcttctgg cagccagaaa aagctgtaaa ggcgggtgat gagtttgcat
    52021 tccagtatcg tctgtactgg agtgcgcaac cgcctgttca ttgcccatta gcgcgcgtta
    52081 tggcgacgcg taccggcatg ggcggtttcc cggaaggttg ggcgccaggt gaacactatc
    52141 ccgaaaaatg ggcgcgtcgt tttgccgtcg atttcgttgg tggtgatctg aaagctgccg
    52201 cacgaaaagg cattgagccg gtgattacgc tttccagtgg ggaagcgaag caaatcgaaa
    52261 ttctctatat tgaacccatt gatggttatc gtattcagtt tgactggtat ccgacttcgg
    52321 actccactga tccggtcgat atgcggatgt atctgcgttg tcagggcgac gctatcagtg
    52381 aaacatggct gtatcagtat ttcccgccag cgccggataa acgtcagtat gttgacgacc
    52441 gcgtgatgag ttaatcgttt tttcttcggc accttcttcg ggaggtgccg tctggttaaa
    52501 cacgatcccg ctcgcatttt tccctaagtt aaatgagtaa tctgatggtg tgtatttcag
    52561 atacaccttg tcagccacta acagggagtg cgtatgtttc cagaatatcg agatttaata
    52621 tcccgtctga aaaacgaaaa tcctcgcttt atgtccttgt tcgataaaca caataaactt
    52681 gatcatgaaa ttgccagaaa ggaaggttcc gacggtcgag ggtacaatgc ggaagtggtc
    52741 cgcatgaaaa aacaaaagct acagttaaaa gatgagatgc tcaaaatcct gcagcaggag
    52801 agcgtcaaag aggtataaac tttcctaagc cgccagccag gcggcttttt taacaactgc
    52861 atggattgac tggagataag atgactgaaa cgataaaagt aagcgaatca cttgaattac
    52921 atgctgttgc agaaaatcac gtcactcctc tttatcagtt aatctgtaaa aataaaacct
    52981 ggttacagca gtcgctaaac tggccgcagt tcgttcagag tgaagaggac acgcgaaaaa
    53041 cggtgcaggg taatgtgatg ttgcatcaac gcggctatgc caaaatgttc atgattttca
    53101 aagaagatga acttatcggc gttatctcgt ttaatcgtat tgaaccactg aataaaaccg
    53161 ctgaaatagg ctactggctg gacgaatctc atcaggggca ggggatcatt tctcaggcgc
    53221 tgcaggcatt gattcatcat tacgcccagt ctggtgaact tagacgcttc gtgatcaaat
    53281 gtcgggtgga caatccgcaa agcaaccagg tcgctttgcg caatggtttt atccttgaag
    53341 gttgcctgaa acaggctgag ttcctgaatg atgcctatga tgatgtgaac ttatacgcgc
    53401 gtattatcga ttcataataa ccctgccagc ggcgttcgcg taatgcgctc ctcgccgtta
    53461 atgacttttg gaccacggac atgaaccgtg tcgccatcaa aggcttcaac gacggcgtgg
    53521 tcggttaact ccacatggtt ttcaattatc accgcacctg taatacggct ctcaccttgt
    53581 attacaacgt gctcgtcgag cagaatcggt ccaccacgta ccacggcatt tccgccaatc
    53641 aagacatgat gttttaacac acaattacct tccacaatgg catattccgc cacctgcgaa
    53701 ctgtaatgaa tcgttggaat ggcatcttct tctatgccag ctttcacctg cgcgtgaccg
    53761 tagactttag cgcaatcgca tagccagacg ttgttctctt cattaccttc aatactggca
    53821 aaatcaaaaa cttcggcacg atgttcaata aaagcatacc ggatgacggc atcgccataa
    53881 atttgtgcct ggtggacaat acgcgaggcg ctaacccttg cgcgatcata aatttgtagc
    53941 aggagttgat ggtcaggcgt taagccttgt gctgcgacga tcatagaatg ttgattaatt
    54001 aaggcgtgac caaatattct acattgcccg caaaccagtg agtcatgaat ggtgacactg
    54061 tcacttatat atgcaccctg gctgatttca ctattatcga tccagacatt atccgttgcg
    54121 taaacctctc cccacagtac gctggtgccg gtgatgcgcg tattaccgga aatcaccgtt
    54181 ccgccgaacg caatagcatt ctggtcgtaa atccagcaat ttccttcctg tgctaacacc
    54241 gtttcgcgat cgatccagcc gccagcggtt cctgctatca catcgttaaa atcgctaatg
    54301 gcgataatct gccgtaataa cacatttttt ttagtgccat cttcctgata actaaaggct
    54361 cgctgttctt cacttagacg atatttgcgc atagcgtttt cccacaggtg acttactata
    54421 accgtagcaa attctgcggc tctggctatg ctcgagaaaa ttccataaaa tgcatttcaa
    54481 atatacttta taaattaaac aaaatgagta agaagatgca gagcgataaa gtgctcaatt
    54541 tgccggcagg ctactttggt attgtgttgg ggacgatagg gatgggattt gcctggcgct
    54601 atgccagcca ggtttggcag gtcagccact ggttagggga tgggctggtg attctggcga
    54661 tgatcatctg gggattatta actagcgcat ttattacccg actcatacgc tttccgcata
    54721 gcgtgctggc ggaagttcgc catccagtgc tgagcagttt tgtgagtttg tttccggcaa
    54781 cgacgatgct ggtggcgatt ggttttgttc cgtggtttcg cccactggcg gtgtgcctgt
    54841 tcagttttgg tgtcgtggtt cagttggctt atgccgcctg gcaaactgcg ggattatggc
    54901 gcggatctca ccctgaagaa gctaccacgc ctggactgta tctgccgaca gttgccaaca
    54961 actttatcag cgcaatggcc tgtggtgcgt tgggctacac cgacgccggt ctggtgtttt
    55021 taggcgcagg cgttttctca tggctaagcc ttgaaccggt gatcttgcag cgtctgcgca
    55081 gttcgggaga attacccacg gcactgcgga catcactcgg cattcagctc gctcctgcgc
    55141 tggtggcttg tagtgcctgg ctgagcgtca acggcggcga gggtgacacg ctggcgaaaa
    55201 tgcttttcgg ttatggactg ctgcaactgc tgtttatgct acgtctgatg ccatggtatc
    55261 tctcccagcc atttaatgct tcattctgga gtttctcgtt cggcgtatct gcactggcaa
    55321 ccaccggttt gcatctgggg agtggcagcg ataatggatt tttccatacg ctggcggtgc
    55381 cgctgtttat ctttaccaat tttattattg caatactgct catccgtact tttgcgcttc
    55441 tgatgcaggg aaaattgtta gtcagaaccg agcgcgccgt tttaatgaaa gcagaggaca
    55501 aagaatgatc attcgtgacg aaaactattt tactgataaa tatgaattaa cccgcacaca
    55561 ctctgaagta ctggaagcgg tgaaagtggt taaaccgggt aaaacgctgg atctgggctg
    55621 tggcaatggt cgtaacagtc tttacctggc agccaatggt tatgatgttg acgcatggga
    55681 taaaaatgcc atgagtatcg ccaacgtcga gcgcattaaa tccattgaaa atctggataa
    55741 tttacacacc cgagtcgttg atctgaataa cctcacattt gatagacagt acgattttat
    55801 tctttcgact gtggtactga tgttccttga ggctaaaacc atcccagggc tgattgtcaa
    55861 tatgcaacgt tgcactaaac ctggtggtta caacctgatt gtggcggcga tggataccgc
    55921 tgattatcca tgtaccgtcg gcttcccgtt tgccttcaaa gagggagaat tacgtcgata
    55981 ttacgaaggc tgggagaggg tgaaatacaa tgaagacgtc ggcgagctgc accgcaccga
    56041 cgccaacggt aatcgtatta aactgcgttt cgccacgatg ctggcacgta aaaaatgacc
    56101 cgctaagaat aaggcgcgtg aaaattcccc acgctgagat gatttactgt tcttcttttc
    56161 ggtaagcata ttttttatcg aagggatgtg aaattaatca cagtagtcga agttttttag
    56221 cagcttaact tactgaaatt taactactga tgattgactt agcccctttt tcggcattga
    56281 ctatgtcgtc tgaaaagggg ctgaaaaatt tattttcacc aacacttttt ttgccacaac
    56341 acgaagcggc gctttttgct ataacttaga aagtaatata atcatctcag gaaactattc
    56401 atgcgtacca catcatttgc gaaagttgca gctttatgcg gcttgttggc tctgtctggt
    56461 tgtgcctcta aaatcaccca gccagataaa tattctggtt ttttaaacaa ttactctgat
    56521 ttaaaagaaa caacctcagc aacaggtaaa cctgttttac gttgggtaga cccgagtttt
    56581 gatcaaagca aatatgacag catcgtctgg aacccaatca cttattatcc ggtaccaaaa
    56641 ccttctaccc aggtagggca gaaagttctg gataaaattt tgaactatac caacaccgaa
    56701 atgaaagaag cgatagcgca gcgtaaacca ctggttacca ccgctgggcc gcgtagtctg
    56761 attttccgtg gggccattac cggtgtagat accagcaaag aagggctgca attctatgaa
    56821 gtggttcctg ttgcattagt ggttgcgggg acgcaaatgg ctacaggcca ccgtaccatg
    56881 gatactcgcc tctattttga aggtgagctg attgatgcag cgactaataa accggttatc
    56941 aaagtcgttc gtcagggcga aggtaaagac ctgaataacg aaagtacgcc aatggctttc
    57001 gaaaatatta aacaagttat tgatgacatg gcgaccgatg ccaccatgtt tgacgttaac
    57061 aaaaagtagt tccagacgcg ccatcgttag atggcgcttt ttatccggtg cgccgtaaaa
    57121 ccccatcctt cagggcgggg atataaggcg cggttttcca cctgaccagg tgtttgctgt
    57181 tgttcaatgt attggcggat gacggatatt ggcgcacctc cgcagctact ggcaaaatag
    57241 ccaggactcc acaaaacgcc tttgtagtaa tacctgactg caatatctgg tcgatctcgt
    57301 cgcagtaacc tactcgatac gcctttgagg ctgtttacca gactggatat cgccagtttg
    57361 ggaggatagt taattaacaa atggacgtga tctggttcgc catccattta aaccagttca
    57421 gcttcaaaat cag
//
LOCUS       DAPGUL010000017        57362 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.017, whole genome shotgun sequence.
ACCESSION   DAPGUL010000017 DAPGUL010000000
VERSION     DAPGUL010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 57362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57362
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.017"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(106..651)
                     /gene="syd"
                     /locus_tag="RHX21_001167"
     CDS             complement(106..651)
                     /gene="syd"
                     /locus_tag="RHX21_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SecY-interacting protein"
                     /protein_id="HDV1986389.1"
                     /translation="MDDLTAQALKDFTARYCDAWHEEHKSWPLSEELYGVPSPCIIST
                     TEDAVYWQPQPFTGEQNVNAVERAFDIVIQPTIHTFYTTQFAGDMHAQFGDIKLTLLQ
                     TWSEDDFRRVQENLIGHLVTQKRLKLPPTLFIATLEEELEVISVCNLSGEVCKETLGT
                     RKRTHLASNLAEFLNQLKPLL"
     gene            719..1567
                     /gene="queF"
                     /locus_tag="RHX21_001168"
     CDS             719..1567
                     /gene="queF"
                     /locus_tag="RHX21_001168"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HDV1986390.1"
                     /translation="MSSYANHQALAGLTLGKSTDYRDTYDANLLQGVPRSLNRDPLGL
                     KADNLPFHGTDIWTLYELSWLNAKGLPQVAVGHVELDYTSVNLIESKSFKLYLNSFNQ
                     TRFNNWDEVRQTLERDLSTCAQGKVSVALYRLDELEGQPIGHFNGTCIDDQDITIDNY
                     EFTTDYLENATSGEKVVEETLVSHLLKSNCLITHQPDWGSIQIQYRGRQIDREKLLRY
                     LVSFRHHNEFHEQCVERIFNDLLRFCQPEKLSVYARYTRRGGLDINPWRSNSDFVPST
                     TRLVRQ"
     gene            1679..3043
                     /gene="ppnN"
                     /locus_tag="RHX21_001169"
                     /gene_synonym="ygdH"
     CDS             1679..3043
                     /gene="ppnN"
                     /locus_tag="RHX21_001169"
                     /gene_synonym="ygdH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide 5'-monophosphate nucleosidase"
                     /protein_id="HDV1986391.1"
                     /translation="MITHISPLGSMDMLSQLEVDMLKRTASSDLYQLFRNCSLAVLNS
                     GSLTDNSKELLSRFENFDINVLRRERGVKLELINPPEEAFVDGRIIRALQANLFAVLR
                     DILFVYGQIHNTVRFPNLNLDNSVHITNLVFSILRNARALHVGEAPNMVVCWGGHSIN
                     ENEYLYARRVGNQLGLRELNICTGCGPGAMEAPMKGAAVGHAQQRYKDSRFIGMTEPS
                     IIAAEPPNPLVNELIIMPDIEKRLEAFVRIAHGIIIFPGGVGTAEELLYLLGILMNPA
                     NKDQVLPLILTGPKESADYFRVLDEFVVHTLGENARRHYRIIIDDAAEVARQMKKSMP
                     LVKENRRDTGDAYSFNWSMRIAPDLQMPFEPSHENMANLKLYPDQPVEVLAADLRRAF
                     SGIVAGNVKEVGIRAIEEFGPYKINGDKEIMRRMDDLLQGFVAQHRMKLPGSAYIPCY
                     EICT"
     gene            3600..4889
                     /gene="sdaC"
                     /locus_tag="RHX21_001170"
     CDS             3600..4889
                     /gene="sdaC"
                     /locus_tag="RHX21_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease SdaC"
                     /protein_id="HDV1986392.1"
                     /translation="METTQTSTIASKDSRSAWRKTDTMWMLGLYGTAIGAGVLFLPIN
                     AGVGGMIPLIIMAILAFPMTFFAHRGLTRFVLSGKNPGEDITEVVEEHFGIGAGKLIT
                     LLYFFAIYPILLVYSVAITNTVESFMSHQLGMTPPPRAILSLILIVGMMTIVRFGEQM
                     IVKAMSILVFPFVGVLMLLALYLIPQWNGAALETLSLDTASATGNGLWMTLWLAIPVM
                     VFSFNHSPIISSFAVAKREEYGDMAEQKCSKILAFAHIMMVLTVMFFVFSCVLSLTPA
                     DLAAAKEQNISILSYLANHFNAPVIAWMAPIIAIIAITKSFLGHYLGAREGFNGMVIK
                     SLRGKGKSIEINKLNRITALFMLVTTWIVATLNPSILGMIETLGGPIIAMILFLMPMY
                     AIQKVPAMRKYSGHISNVFVVVMGLIAISAIFYSLFS"
     gene            4947..6314
                     /gene="sdaB"
                     /locus_tag="RHX21_001171"
     CDS             4947..6314
                     /gene="sdaB"
                     /locus_tag="RHX21_001171"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase II"
                     /protein_id="HDV1986393.1"
                     /translation="MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARNLLKDVTR
                     VVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDIDSIPGFIQDVNTHGRLMLANGQ
                     HEVEFPVDQCMNFHADNLSLHENGMRITALAGDKVVYSQTYYSIGGGFIVDEEHFGQQ
                     NSAPVEVPYPYSSAADLQKHCQETGLSLSGLMMKNELALHSKEELEQHLANVWEVMRG
                     GIERGISTEGVLPGKLRVPRRAAALRRMLVSQDKTTTDPMAVVDWINMFALAVNEENA
                     AGGRVVTAPTNGACGIIPAVLAYYDKFIREVNANSLARYLLVASAIGSLYKMNASISG
                     AEVGCQGEVGVACSMAAAGLAELLGASPAQVCIAAEIAMEHNLGLTCDPVAGQVQVPC
                     IERNAIAAVKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSRGGLAMK
                     IVACD"
     gene            6426..7181
                     /gene="xni"
                     /locus_tag="RHX21_001172"
     CDS             6426..7181
                     /gene="xni"
                     /locus_tag="RHX21_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417278.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flap endonuclease Xni"
                     /protein_id="HDV1986394.1"
                     /translation="MAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTH
                     AVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHDEMPALRAAFEQRGVPCWSTSGNE
                     ADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGV
                     QPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFQSLEGIYENLDAVAEKWRKKL
                     ETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR"
     gene            complement(7236..8384)
                     /gene="fucO"
                     /locus_tag="RHX21_001173"
     CDS             complement(7236..8384)
                     /gene="fucO"
                     /locus_tag="RHX21_001173"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417279.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HDV1986395.1"
                     /translation="MANRMILNETAWFGRGAVGALTDEVKRRGYQKALIVTDKTLVQC
                     GVVAKVTDKMDAAGLAWAIYDGVVPNPTITVVKEGLGVFQNSGADYLIAIGGGSPQDT
                     CKAIGIISNNPEFADVRSLEGLSPTNKTSVPILAIPTTAGTAAEVTINYVITDEEKRR
                     KFVCVDPHDIPQVAFIDADMMDGMPPALKAATGVDALTHAIEGYITRGAWALTDALHI
                     KAIEIIAGALRGSVAGDKDAGEEMALGQYVAGMGFSNVGLGLVHGMAHPLGAFYNTPH
                     GVANAILLPHVMRYNADFTGEKYRDIARVMGVKVEGMSLEEARNAAVEAVFALNRDVG
                     IPPHLRDVGVRKEDIPALAQAALDDVCTGGNPREATLEDIVELYHTAW"
     gene            complement(8412..9059)
                     /gene="fucA"
                     /locus_tag="RHX21_001174"
     CDS             complement(8412..9059)
                     /gene="fucA"
                     /locus_tag="RHX21_001174"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HDV1986396.1"
                     /translation="MERNKLARQIIDTCLEMTRLGLNQGTAGNVSVRYQDGMLITPTG
                     IPYEKLTESHIVFIDGNGKHEEGKLPSSEWRFHMAAYQSRPDANAVVHNHAVHCTAVS
                     ILNRSIPAIHYMIAAAGGNSIPCAPYATFGTRELSEHVAQALKNRKATLLQHHGLIAC
                     EVNLEKALWLAHEVEVLAQLYLTTLAITDPVPVLSDEEIAVVLEKFKTYGLRIEE"
     gene            9606..10922
                     /gene="fucP"
                     /locus_tag="RHX21_001175"
     CDS             9606..10922
                     /gene="fucP"
                     /locus_tag="RHX21_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose:H+ symporter permease"
                     /protein_id="HDV1986397.1"
                     /translation="MGNTSIQTQSYRAVDKDAGQSRSYIIPFALLCSLFFLWAVANNL
                     NDILLPQFQQAFTLTNFQAGLIQSAFYFGYFIIPIPAGILMKKLSYKAGIITGLFLYA
                     LGAALFWPAAEIMNYTLFLVGLFIIAAGLGCLETAANPFVTVLGPESSGHFRLNLAQT
                     FNSFGAIIAVVFGQSLILSNVPHQSQDVLDKMSPEQLSAYKHSLVLSVQTPYMIIVAI
                     VLLVALLIMLTKFPALQSDNHSDAKQGSFSASLSRLARIRHWRWAVLAQFCYVGAQTA
                     CWSYLIRYAVEEIPGMTAGFAANYLTGTMVCFFIGRFTGTWLISRFAPHKVLAAYALI
                     AMALCLISAFAGGHVGLIALTLCSAFMSIQYPTIFSLGIKNLGQDTKYGSSFIVMTII
                     GGGIVTPVMGFVSDAAGNIPTAELIPALCFAVIFIFARFRSQTATN"
     gene            10955..12730
                     /gene="fucI"
                     /locus_tag="RHX21_001176"
     CDS             10955..12730
                     /gene="fucI"
                     /locus_tag="RHX21_001176"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HDV1986398.1"
                     /translation="MKKISLPKIGIRPVIDGRRMGVRESLEEQTMNMAKATAALLTEK
                     LRHACGAAVECVISDTCIAGMAEAAACEEKFSSQNVGLTITVTPCWCYGSETIDMDPT
                     RPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLL
                     RFARAGLAVASMKGKSYLSLGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRID
                     QKIYDEAELEMALTWADKNFRYGEDENNKQYQRNAEQSRAVLRESLLMAMCIRDMMQG
                     NSKLADIGRVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEAILNSSFDWNGVREPFVV
                     ATENDSLNGVAMLMGHQLTGTAQVFADVRTYWSPEAIERVTGHKLDGLAEHGIIHLIN
                     SGSAALDGSCKQRDSEGNPTMKPHWEISQQEADACLAATEWCPAIHEYFRGGGYSSRF
                     LTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVELPKDVHDILNKRTNSTWPTTWFAPRL
                     TGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLASMLRIPVCMHNVEETKVYRPSA
                     WAAHGMDIEGQDYRACQNYGPLYKR"
     gene            12839..14257
                     /gene="fucK"
                     /locus_tag="RHX21_001177"
     CDS             12839..14257
                     /gene="fucK"
                     /locus_tag="RHX21_001177"
                     /EC_number="2.7.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417283.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculokinase"
                     /protein_id="HDV1986399.1"
                     /translation="MKQEVILVLDCGATNVRAIAVNRQGKIVARASTPNASDIAMENN
                     TWHQWSLDAILQRFADCCRQINSELTECHIRGIAVTTFGVDGALVDKQGNLLYPIISW
                     KCPRTAAVMDNIEQLISAQRLQAISGVGAFSFNTLYKLVWLKENHPQLLERAHAWLFI
                     SSLINHRLTGEFTTDITMAGTSQMLDIQQRDFSPQILQATGIPRRLFPRLVEAGEQIG
                     TLQNSAAAMLGLPVGIPVISAGHDTQFALFGAGADQNEPVLSSGTWEILMVRSAQVDT
                     SLLSQYAGSTCELDSQAGLYNPGMQWLASGVLEWVRKLFWTAETPWQMLIEEARLIAP
                     GADGVKMQCDLLSCQNAGWQGVTLNTTRGHFYRAALEGLTAQLQRNLQMLEKIGHFKA
                     SELLLVGGGSRNTLWNQIKANMLDIPVKVLDDAETTVAGAALFGWYGVGEFNSPEEAR
                     AQIHYQYRYFYPQTEPEFIEEV"
     gene            14259..14681
                     /gene="fucU"
                     /locus_tag="RHX21_001178"
     CDS             14259..14681
                     /gene="fucU"
                     /locus_tag="RHX21_001178"
                     /EC_number="5.1.3.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose mutarotase"
                     /protein_id="HDV1986400.1"
                     /translation="MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIR
                     ADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDI
                     IRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP"
     gene            14739..15470
                     /gene="fucR"
                     /locus_tag="RHX21_001179"
     CDS             14739..15470
                     /gene="fucR"
                     /locus_tag="RHX21_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose operon activator"
                     /protein_id="HDV1986401.1"
                     /translation="MKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQT
                     QGKILRNHGRAKYIHRQNQDSGDPFHIRLKSHYAHKADIAREALAWIEEGMVIALDAS
                     STCWYLARQLPDINIQVFTNSHPICHELGKRERIQLISSGGTLERKYGCYVNPSLISQ
                     LKSLEIDLFIFSCEGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEA
                     RIGHLDEVTHIISDERQVATSLVTA"
     gene            complement(15514..16614)
                     /gene="rlmM"
                     /locus_tag="RHX21_001180"
     CDS             complement(15514..16614)
                     /gene="rlmM"
                     /locus_tag="RHX21_001180"
                     /EC_number="2.1.1.186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010435097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (cytidine(2498)-2'-O)-methyltransferase
                     RlmM"
                     /protein_id="HDV1986402.1"
                     /translation="MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIY
                     ECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGE
                     LRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYT
                     GYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDL
                     GACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVC
                     DMVEKPAKVAALMAQWLVNGWCRETIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINA
                     QIQARQLYHDREEVTVHVRRIWAAVGGRRDER"
     gene            complement(16607..17002)
                     /locus_tag="RHX21_001181"
     CDS             complement(16607..17002)
                     /locus_tag="RHX21_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF423 domain-containing protein"
                     /protein_id="HDV1986403.1"
                     /translation="MTSRFMLIFAAISGFIFVALGAFGAHVLSKTMGAVEMGWIQTGL
                     EYQAFHTLAILGLAVAMQRRISIWFYWSSVFLALGTVLFSGSLYCLALSHLRLWAFVT
                     PVGGVSFLAGWALMLVGAIRLKRKGVSHE"
     gene            complement(17021..17938)
                     /gene="gcvA"
                     /locus_tag="RHX21_001182"
     CDS             complement(17021..17938)
                     /gene="gcvA"
                     /locus_tag="RHX21_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system transcriptional
                     regulator GcvA"
                     /protein_id="HDV1986404.1"
                     /translation="MSKRLPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSL
                     EDFLGLKLFRRRNRSLLLTEEGQSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLLP
                     SFAIHWLVPRLSSFNSAYPGIDVRIQAVDRQEDKLADDVDVAIFYGRGNWPGLRVEKL
                     YAEYLLPVCSPLLLTGEKPLKTPEDLAKHTLLHDASRRDWQTYTRQLGLNHINVQQGP
                     IFSHSAMVLQAAIHGQGVALANNVMAQSEIEAGRLVCPFNDVLVSKNAFYLVCHDSQA
                     ELGKIAAFRQWILAKAAAEQEKFRFRYEQ"
     gene            complement(18289..18516)
                     /locus_tag="RHX21_001183"
     CDS             complement(18289..18516)
                     /locus_tag="RHX21_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417289.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgdI/YgdR family lipoprotein"
                     /protein_id="HDV1986405.1"
                     /translation="MKKTAAIISACMLTFALSACSGSNYVMHTNDGRTIVSDGKPQTD
                     NDTGMISYKDANGNKQQINRTDVKEMVELDQ"
     gene            18708..19913
                     /gene="csdA"
                     /locus_tag="RHX21_001184"
     CDS             18708..19913
                     /gene="csdA"
                     /locus_tag="RHX21_001184"
                     /EC_number="3.13.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase CsdA"
                     /protein_id="HDV1986406.1"
                     /translation="MNVFNPAQFRAQFPALQDAGVYLDSAATALKPEAVVEATQQFYS
                     LSAGNVHRSQFAEAQRLTARYEAAREKVAQLLNAPDDKTIVWTRGTTESINMVAQCYA
                     RPRLQPGDEIIVSVAEHHANLVPWLMVAQQTGAKVVKLPLNAQRLPDVDLLPELITPR
                     SRILALGQMSNVTGGCPDLARAITFAHSAGMVVMVDGAQGAVHFPADVQQLDIDFYAF
                     SGHKLYGPTGIGVLYGKSELLEAMSPWLGGGKMVHEVSFDGFTTQSAPWKLEAGTPNV
                     AGVIGLSAALEWLADYDINQAESWSRSLATLAEDALAKRPGFRSFRCQDSSLLAFDFA
                     GVHHSDMVTLLAEYGIALRAGQHCAQPLLAELGVTGTLRASFAPYNTKSDVDALVNAV
                     DRALELLVD"
     gene            19913..20356
                     /gene="csdE"
                     /locus_tag="RHX21_001185"
     CDS             19913..20356
                     /gene="csdE"
                     /locus_tag="RHX21_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase sulfur acceptor subunit
                     CsdE"
                     /protein_id="HDV1986407.1"
                     /translation="MTNPQFAGHPFGTTVTAETLRNTFAPLSQWEDKYRQLIMLGKQL
                     PALPDELKAQAKEIAGCENRVWLGYTVTENGKMHFFGDSEGRIVRGLLAVLLTAVEGK
                     TVAELQAQSPLALFDELGLRAQLSASRSQGLNALSEAIIAAAKQV"
     gene            complement(20407..21213)
                     /gene="tcdA"
                     /locus_tag="RHX21_001186"
     CDS             complement(20407..21213)
                     /gene="tcdA"
                     /locus_tag="RHX21_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA cyclic N6-threonylcarbamoyladenosine(37)
                     synthase TcdA"
                     /protein_id="HDV1986408.1"
                     /translation="MSVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSW
                     AAEALARTGIGAITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRV
                     TVVDDFVTPDNVAQYMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQID
                     PTQIQVTDLAKTIQDPLAAKLRERLKSDFGVVKNSKGKLGVDCVFSTEALVYPQSDGT
                     VCAMKATAEGPKRMDCASGFGAATMVTATFGFVAVSHALKKMMAKAARQG"
     gene            complement(21290..22387)
                     /gene="mltA"
                     /locus_tag="RHX21_001187"
     CDS             complement(21290..22387)
                     /gene="mltA"
                     /locus_tag="RHX21_001187"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase A"
                     /protein_id="HDV1986409.1"
                     /translation="MKGRWVKYLLMGTVVAMLAACSSKPTDRGQQYKDGKFTQPFSLV
                     NQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRAGGDTRNMRQFGI
                     DAWQMEGADNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLPSRAEIYAGA
                     LSDKYILAYSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVLIDR
                     GEVKKEDMSMQAIRHWGETHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLVGRA
                     SVASDRSIIPPGTTLLAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFDIYQGIG
                     PEAGHRAGWYNHYGRVWVLKTAPGAGNVFSG"
     gene            22596..22672
                     /locus_tag="RHX21_001188"
     tRNA            22596..22672
                     /locus_tag="RHX21_001188"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:22630..22632,aa:Met,seq:cat)
     gene            complement(22747..24000)
                     /gene="amiC"
                     /locus_tag="RHX21_001189"
     CDS             complement(22747..24000)
                     /gene="amiC"
                     /locus_tag="RHX21_001189"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311701.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiC"
                     /protein_id="HDV1986410.1"
                     /translation="MSGSNTAISRRRLLQGAGAMWLLSVSQVSLAAVSQVVAVRVWPA
                     SSYTRVTVESNRQLKYKQFALSNPERVVVDIEDVNLNSVLKGMAAQIRADDPFIKSAR
                     VGQFDPQTVRMVFELKQNVKPQLFALAPVAGFKERLVMDLYPANAQDMQDPLLALLED
                     YNKGDLEKQVPPAQSGPQPGKAGRDRPIVIMLDPGHGGEDSGAVGKYKTREKDVVLQI
                     ARRLRSLIEKEGNMKVYMTRNEDIFIPLQVRVAKAQKQRADLFVSIHADAFTSRQPSG
                     SSVFALSTKGATSTAAKYLAQTQNASDLIGGVSKSGDRYVDHTMFDMVQSLTIADSLK
                     FGKAVLNKLGKINKLHKNQVEQAGFAVLKAPDIPSILVETAFISNVEEERKLKTATFQ
                     QEVAESILAGIKAYFADGATLARRG"
     gene            24232..25563
                     /gene="argA"
                     /locus_tag="RHX21_001190"
     CDS             24232..25563
                     /gene="argA"
                     /locus_tag="RHX21_001190"
                     /EC_number="2.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino-acid N-acetyltransferase"
                     /protein_id="HDV1986411.1"
                     /translation="MVKERKTELVEGFRHSVPYINTHRGKTFVIMLGGEAIEHENFSS
                     IVNDIGLLHSLGIRLVVVYGARPQIDANLAAHHHEPLYHKNIRVTDAKTLELVKQAAG
                     TLQLDITARLSMSLNNTPLQGAHINVVSGNFIIAQPLGVDDGVDYCHSGRIRRIDEDA
                     IHRQLDSGAIVLMGPVAVSVTGESFNLTSEEIATQLAIKLKAEKMIGFCSSQGVTNDD
                     GDIVSELFPNEAQARVEAQEEKGDYNSGTVRFLRGAVKACRSGVRRCHLISYQEDGAL
                     LQELFSRDGIGTQIVMESAEQIRRATINDIGGILELIRPLEQQGILVRRSREQLEMEI
                     DKFTIIQRDNTTIACAALYPFPEEKIGEMACVAVHPDYRSSSRGEVLLERITAQAKQS
                     GLSKLFVLTTRSIHWFQERGFTPVDIDLLPESKKQLYNYQRKSKVLMADLG"
     gene            complement(25625..27451)
                     /gene="recD"
                     /locus_tag="RHX21_001191"
     CDS             complement(25625..27451)
                     /gene="recD"
                     /locus_tag="RHX21_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit alpha"
                     /protein_id="HDV1986412.1"
                     /translation="MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSH
                     DAGEGHVCLPLSRLENNEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMIL
                     CGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAV
                     ALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGK
                     ALRQLPLTDEQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDL
                     PMMSRLIDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAGFTAERAGQLSRLTG
                     THVPAGTGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVKTVFQQDFTD
                     IEKRLLQSGEDYIAMLEEALAGYGRYLDLLQARAEPDLIIQAFNEYQLLCALREGPFG
                     VAGLNERIEQFMQQKRKIHRHPHSRWYEGRPVMIARNDSALGLFNGDIGIALDRGQGT
                     RVWFAMPDGNIKSVQPSRLPEHETTWAMTVHKSQGSEFDHAALILPSQRTPVVTRELV
                     YTAVTRARRRLSLYADERILSAAIATRTERRSGLAALFSSRE"
     gene            complement(27451..30993)
                     /gene="recB"
                     /locus_tag="RHX21_001192"
     CDS             complement(27451..30993)
                     /gene="recB"
                     /locus_tag="RHX21_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708611.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit beta"
                     /protein_id="HDV1986413.1"
                     /translation="MSDVAETLDPLRLPLQGERLIEASAGTGKTFTIAALYLRLLLGL
                     GGSAAFPRPLTVEELLVVTFTEAATAELRGRIRSNIHELRIACLRETTDNPLYERLLE
                     EIDDKAQAAQWLLLAERQMDEAAVFTIHGFCQRMLNLNAFESGMLFEQQLIEDESLLR
                     YQACADFWRRHCYPLPREIALVVFETWKGPQALLRDINRYLQGEAPVIKAPPPDDETL
                     ASRHAQIVARIDTVKQQWRDAVGELDALIESSGIDRRKFNRSNQAKWIEKISAWAEEE
                     TNSYQLPESLEKFSQRFLEDRTKAGGETPRHPLFEAIEQLLAEPLSIRDLVITRALAE
                     IRETVAREKRRRGELGFDDMLSRLDSALRSESGEVLAAAIRTRFPVAMIDEFQDTDPQ
                     QYRIFRRIWHHQPETALLLIGDPKQAIYAFRGADIFTYMKARSEVHAHYTLDTNWRSA
                     PGMVNSVNKLFSQTDDAFMFREIPFIPVKSAGKNQALRFVFKGETQPAMKMWLMEGES
                     CGVGDYQSTMAQVCAAQIRDWLQAGQRGEALLMNGDDARPVRASDISVLVRSRQEAAQ
                     VRDALTLLEIPSVYLSNRDSVFETLEAQEMLWLLQAVMTPERENTLRSALATSMMGLN
                     ALDIETLNNDEHAWDVVVEEFDGYRQIWRKRGVMPMLRALMSARNIAENLLATAGGER
                     RLTDILHISELLQEAGTQLESEHALVRWLSQHILEPDSNASSQQMRLESDKHLVQIVT
                     IHKSKGLEYPLVWLPFITNFRVQDQAFYHDRHSFEAVLDLNAAPESVDLAEVERLAED
                     LRLLYVALTRSVWHCSLGVAPLVRRRGDKKGDTDVHQSALGRLLQKGEPQDAAGLRTC
                     IEALCDDDIAWQTAQTGDNQPWQVNDALTAELNARTLQRLPGDNWRVTSYSGLQQRGH
                     GIAQDLMPRLDVDAAGVVSVVEEPTLTPHQFPRGASPGTFLHSLFEDLDFTQPVDPNW
                     VQEKLELGGFESQWEPVLTEWITAVLQAPLNETGVSLSQLSDRDKQVEMEFYLPISEP
                     LIASQLDALIRQFDPLSAGCPPLEFMQVRGMLKGFIDLVFRHEGRYYLLDYKSNWLGE
                     DSSAYTQQAMAAAMQAHRYDLQYQLYTLALHRYLRHRIADYDYDRHFGGVIYLFLRGV
                     DKEHPQQGIYTTRPNAGLIALMDEMFAGMTLEEA"
     gene            complement(30986..33874)
                     /gene="ptrA"
                     /locus_tag="RHX21_001193"
     CDS             complement(30986..33874)
                     /gene="ptrA"
                     /locus_tag="RHX21_001193"
                     /EC_number="3.4.24.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pitrilysin"
                     /protein_id="HDV1986414.1"
                     /translation="MPRSTWFKALLLFVALWAPLSQAETGWQPIQETIRKSDKDNRQY
                     QAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYP
                     QADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAE
                     RERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQAL
                     KDFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKG
                     IIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTLSDWLQKQGLVE
                     GISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKGIDKQYFDEL
                     ANVLDIDFRYPSITRDMDYVEWLADTMIRVPVEHTLDAVNIADRYDAKAVKERLAMMT
                     PQNARIWYISPKEPHNKTAYFVDAPYQVDKISEQTFADWQQKAANIALSLPELNPYIP
                     DDFSLIKSEKKYDHPELIVDESNLRVVYAPSRYFSSEPKADVSLILRNPKAMDSARNQ
                     VMFALNDYLAGLALDQLSNQASVGGISFSTNANNGLMVNANGYTQRLPQLFQALLEGY
                     FSYTATEDQLEQAKSWYNQMMDSAEKGKAFEQAIMPAQMLSQVPYFSRDERRKILPSI
                     TLKEVLAYRDALKSGARPEFMVIGNMTEAQATTLARDVQKQLGADGSEWCRNKDVVVD
                     KKQSVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQLRTEEQLG
                     YAVFAFPMSVGRQWGMGFLLQSNDKQPSFLWERYKAFFPTAEAKLRAMKPDEFAQIQQ
                     AVITQMLQAPQTLGEEASKLSKDFDRGNMRFDSRDKIVAQIKLLTPQKLADFFHQAVV
                     EPQGMAILSQISGSQNGKAEYVHPEGWKVWENVSALQQTMPLMSEKNE"
     gene            complement(34050..37418)
                     /gene="recC"
                     /locus_tag="RHX21_001194"
     CDS             complement(34050..37418)
                     /gene="recC"
                     /locus_tag="RHX21_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit gamma"
                     /protein_id="HDV1986415.1"
                     /translation="MLRVYHSNRLDVLEALMEFIVERERLDDPFEPEMILVQSTGMAQ
                     WLQMTLSQKFGIAANIDFPLPASFIWDMFVRVLPEIPKESAFNKQSMSWKLMTLLPQL
                     LDREDFTLLRHYLTDDSDKRKLFQLSSKAADLFDQYLVYRPEWLAQWETGHLVEGLGE
                     AQAWQAPLWKALVEYTHELGQPRWHRANLYQRFIETLESATTCPPGLPSRVFICGISA
                     LPPVYLQALQALGKHIEIHLLFTNPCRYYWGDIKDPAYLAKLLTRQRRHSFEDRELPL
                     FRDSENAGQLFNSDGEQDVGNPLLASWGKLGRDYIYLLSDLESSQELDAFVDVTPDNL
                     LHNIQSDILELENRAVAGVNIEEFSRSDNKRPLDPLDSSITFHVCHSPQREVEVLHDR
                     LLAMLEEDPTLTPRDIIVMVADIDSYSPFIQAVFGSAPADRYLPYAISDRRARQSHPV
                     LEAFISLLSLPDSRFVSEDVLALLDVPVLAARFDITEEGLRYLRQWVNESGIRWGIDD
                     DNVRELELPTTGQHTWRFGLTRMLLGYAMESAQGEWQSVLPYDESSGLIAELVGHLAS
                     LLMQLNIWRRGLAQERPLEEWLPVCRDMLNAFFLPDAETEAAMTLIEQQWQAIIAEGL
                     GAQYGDAVPLSLLRDELAQRLDQERISQRFLAGPVNICTLMPMRSIPFKVVCLLGMND
                     GVYPRQLAPLGFDLMSQKPKRGDRSRRDDDRYLFLEALISAQQKLYISYIGRSIQDNS
                     ERFPSVLVQELIDYIGQSHYLPGDEALNCDESEVRVKAHLTCLHTRMPFDPQNYQPGE
                     RQSYAREWLPAASQAGKAHSEFVQPLPFTLPETVPLETLQRFWAHPVRAFFQMRLQVN
                     FRTEDSEIPDTEPFILEGLSRYQINQQLLNALVEQDDAERLFRRFRAAGDLPYGAFGE
                     IFWETQCQEMQQLADRVIACRQPGQSMEIDLACNGVQITGWLPQVQPDGLLRWRPSLL
                     SVAQGMQLWLEHLVYCASGGNGESRLFLRKDGEWRFPPLAAEQALHYLSQLIEGYREG
                     MSAPLLVLPESGGAWLKTCYDAQNDAMLDDDSTLQKARTKFLQAYEGNMMVRGEGDDI
                     WYQRLWRQLTPETMEAIVEQSQRFLLPLFRFNQS"
     gene            complement(37431..37754)
                     /locus_tag="RHX21_001195"
     CDS             complement(37431..37754)
                     /locus_tag="RHX21_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDV1986416.1"
                     /translation="MSASLKNQQGFSLPEVMVAMVLMVMIVTALSGIQRTLMNSLASR
                     NQYQQLWRHGWQQTQLRAISPPANWQVNRMQTSQAGCVSISVTLVSPGGREGEMTRLH
                     CPNRQ"
     gene            complement(37739..38146)
                     /locus_tag="RHX21_001196"
     CDS             complement(37739..38146)
                     /locus_tag="RHX21_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417301.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2509 family protein"
                     /protein_id="HDV1986417.1"
                     /translation="MNREKGVSSLALVLMLLVLGSLLLQGMSQQDRSFASRVSMESQS
                     LRRQAIVQSALAWGKMHSWQTQPAVQCSQYAGTDARVCLRLLADNEALLVAGYEGVSL
                     WRTGEVIDGNIVFSPRGWSDFCPLKERALCQLP"
     gene            complement(38143..38706)
                     /locus_tag="RHX21_001197"
     CDS             complement(38143..38706)
                     /locus_tag="RHX21_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent protein"
                     /protein_id="HDV1986418.1"
                     /translation="MPVKEQGFSLLEVLIAMAISSVLLLGAARFLPALQRESLTSTRK
                     LALEDEIWLRVFTVAKHLQRAGYCHGSCTGEGLEIVGQGDCIIVQWDANSNGIWDREP
                     VKESDQIGFRLKEHVLETLRGATSCEGKGWDKVTNPDAIIIDTFQVVRQDVSGFSPVL
                     TVNMRAASKSEPQTVVDASYSVTGFNL"
     gene            complement(38697..39167)
                     /locus_tag="RHX21_001198"
     CDS             complement(38697..39167)
                     /locus_tag="RHX21_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent protein"
                     /protein_id="HDV1986419.1"
                     /translation="MKTQRGYTLIETLVAMLILVMLSASGLYGWQYWQQSQRLWQTAS
                     QARDYLLYLREDANWHNRDHSISVIREGTLWCLVSSAAGANTCHGSSPLVFVPRWPEV
                     EMSDLTPSLAFFGLRNTAWAGHIRFKNSTGEWWLVVSPWGRLRLCQQGETEGCL"
     gene            complement(39352..40146)
                     /gene="thyA"
                     /locus_tag="RHX21_001199"
     CDS             complement(39352..40146)
                     /gene="thyA"
                     /locus_tag="RHX21_001199"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HDV1986420.1"
                     /translation="MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPL
                     VTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWP
                     TPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLS
                     CQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHL
                     QLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGIKAPVAI"
     gene            complement(40153..41028)
                     /gene="lgt"
                     /locus_tag="RHX21_001200"
     CDS             complement(40153..41028)
                     /gene="lgt"
                     /locus_tag="RHX21_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HDV1986421.1"
                     /translation="MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRR
                     ANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFMADPLYLFRVWDGGMSF
                     HGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNF
                     PFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYI
                     RKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVI
                     MMVWAYRRSPQQHVS"
     gene            complement(41179..43425)
                     /gene="ptsP"
                     /locus_tag="RHX21_001201"
     CDS             complement(41179..43425)
                     /gene="ptsP"
                     /locus_tag="RHX21_001201"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDV1986422.1"
                     /translation="MLTRLREIVEKVASAPRLNEALNILVTDICLAMDTEVCSVYLAD
                     HDRRCYYLMATRGLKKPRGRTVTLAFDEGIVGLVGRLAEPINLADAQKHPSFKYIPSV
                     KEERFRAFLGVPIIQRRQLLGVLVVQQRELRQYDESEESFLVTLATQMAAILSQSQLT
                     ALFGQYRQTRIRALPAAPGVAIAEGWQDATLPLMEQVYQASTLDPALERERLTGALEE
                     AANEFRRYSKRFAAGAQKETAAIFDLYSHLLSDTRLRRELFAEVDKGSVAEWAVKTVI
                     EKFAEQFAALSDNYLKERAGDLRALGQRLLFHLDDANQGPNAWPERFILVADELSATT
                     LAELPQDRLVGVVVRDGAANSHAAIMVRALGIPTVMGADIQPSVLHRRTLIVDGYRGE
                     LLVDPEPVLLQEYQRLISEEIELSRLAEDDVNLPAQLKSGERIKVMLNAGLSPEHEEK
                     LGSRIDGIGLYRTEIPFMLQSGFPSEEEQVAQYQGMLQMFNDKPVTLRTLDVGADKQL
                     PYMPISEENPCLGWRGIRITLDQPEIFLIQVRAMLRANAATGNLNILLPMVTSLDEVD
                     EARRLIERAGREVEEMIGYEIPKPRIGIMLEVPSMVFMLPHLAKRVDFISVGTNDLTQ
                     YILAVDRNNTRVANIYDSLHPAMLRALAMIAREAEIHGIDLRLCGEMAGDPMCVAILI
                     GLGYRHLSMNGRSVARVKYLLRRIDYAEAENLAQRSLEAQLATEVRHQVAAFMERRGM
                     GGLIRGGL"
     gene            complement(43438..43968)
                     /gene="rppH"
                     /locus_tag="RHX21_001202"
     CDS             complement(43438..43968)
                     /gene="rppH"
                     /locus_tag="RHX21_001202"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001655775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA pyrophosphohydrolase"
                     /protein_id="HDV1986423.1"
                     /translation="MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGE
                     SAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLL
                     QLVSGDAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRRVMKEFASVVMSLQE
                     NTPKPQNASAYRRKRG"
     gene            44653..45342
                     /gene="mutH"
                     /locus_tag="RHX21_001203"
     CDS             44653..45342
                     /gene="mutH"
                     /locus_tag="RHX21_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutH"
                     /protein_id="HDV1986424.1"
                     /translation="MSQPRPLLSPPETEEQLLAQAQQLSGYTLGELAALAGLVTPENL
                     KRDKGWIGVLLEIWLGASAGSKPEQDFAALGVELKTIPVDSLGRPLETTFVCVAPLTG
                     NSGVTWETSHVRHKLKRVLWIPVEGERSIPLAQRRVGSPLLWSPNEEEDRQLREDWEE
                     LMDMIVLGQVERITARHGEYLQIRPKAANAKALTEAIGARGERILTLPRGFYLKKNFT
                     SALLARHFLIQ"
     gene            45411..46124
                     /locus_tag="RHX21_001204"
     CDS             45411..46124
                     /locus_tag="RHX21_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HDV1986425.1"
                     /translation="MLFAWITDPNAWLALGTLTLLEIVLGIDNIIFLSLVVAKLPTAQ
                     RAHARRLGLAGAMVMRLALLASIAWVTRLTNPLFTIFSQEISARDLILLLGGLFLIWK
                     ASKEIHESIEGEEEGLKTRVSSFLGAIVQIMLLDIIFSLDSVITAVGLSDHLFIMMAA
                     VVIAVGVMMFAARSIGDFVERHPSVKMLALSFLILVGFTLILESFDIHVPKGYIYFAM
                     FFSIAVESLNLIRNKKNPL"
     gene            46262..46480
                     /gene="ygdR"
                     /locus_tag="RHX21_001205"
     CDS             46262..46480
                     /gene="ygdR"
                     /locus_tag="RHX21_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein YgdR"
                     /protein_id="HDV1986426.1"
                     /translation="MKKWAVIISAVGLAFAVSGCSSDYVMATKDGRMILTDGKPEIDD
                     DTGLVSYHDQQGNAMQINRDDVSQIIER"
     gene            46588..47628
                     /locus_tag="RHX21_001206"
     CDS             46588..47628
                     /locus_tag="RHX21_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(H)-dependent aldo-keto reductase"
                     /protein_id="HDV1986427.1"
                     /translation="MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGI
                     NLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPD
                     QALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDT
                     LDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVG
                     LAEVSQYEGVELLAYSCLGFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAA
                     YVDIARRHGLDPAQMALAFVRRQPFVASTLLGATTMDQLKTNIESLHLELSEDVLAEI
                     EAVHQVYTYPAP"
     gene            complement(47660..48853)
                     /gene="lplT"
                     /locus_tag="RHX21_001207"
     CDS             complement(47660..48853)
                     /gene="lplT"
                     /locus_tag="RHX21_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid transporter LplT"
                     /protein_id="HDV1986428.1"
                     /translation="MSESVHTNTSLWSKGMKAVIVAQFLSAFGDNALLFATLALLKAQ
                     FYPEWSQPILQMVFVGAYILFAPFVGQVADSFAKGRVMMFANGLKLLGAASICFGINP
                     FLGYTLVGVGAAAYSPAKYGILGELTTGSKLVKANGLMEASTIAAILLGSVAGGVLAD
                     WHVLVALAACALAYGGAVVANIYIPKLAAARPGQSWNLINMTRSFLNACTSLWRNGET
                     RFSLVGTSLFWGAGVTLRFLLVLWVPVALGITDNATPTYLNAMVAIGIVVGAGAAAKL
                     VTLETVSRCMPAGILIGVVVLIFSLQHELLPAYALLMLIGVMGGFFVVPLNALLQERG
                     KKSVGAGNAIAVQNLGENSAMLLMLGIYSLAVMIGIPVVPIGIGFGALFALAITALWI
                     WQRRH"
     gene            complement(48846..51005)
                     /gene="aas"
                     /locus_tag="RHX21_001208"
     CDS             complement(48846..51005)
                     /gene="aas"
                     /locus_tag="RHX21_001208"
                     /EC_number="2.3.1.40"
                     /EC_number="6.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acyl-ACP--phospholipid
                     O-acyltransferase/long-chain-fatty-acid--ACP ligase"
                     /protein_id="HDV1986429.1"
                     /translation="MLFSFFRNLCRVLYRVRVTGDTQALKGERVLITPNHVSFIDGIL
                     LGLFLPVRPVFAVYTSISQQWYMRWLKSFIDFVPLDPTQPMAIKHLVRLVEQGRPVVI
                     FPEGRITTTGSLMKIYDGAGFVAAKSGATVIPVRIEGAELTHFSRLKGLVKRRLFPQI
                     TLHILPPTQVAMPDAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLSAMYRFG
                     AGKKCVEDVNFTPDSYRKLLTKTLFVGRILEKYSVEGERIGLMLPNAGISAAVIFGAI
                     ARRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLPEQLTQVRWVYLE
                     DLKADVTTADKVWIFAHLLMPRLAQVKQQPEEEALILFTSGSEGHPKGVVHSHKSILA
                     NVEQIKTIADFTTNDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPEL
                     VYDRSCTVLFGTSTFLGHYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRIL
                     EGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLSVPGIEEGGRLQLKGPNIMNG
                     YLRVEKPGVLEVPTAENVRGEMERGWYDTGDIVRFDEQGFVQIQGRAKRFAKIAGEMV
                     SLEMVEQLALGVSPDKVHATAIKSDASKGEALVLFTTDNELTRDKLQQYAREHGVPEL
                     AVPRDIRYLKQMPLLGSGKPDFVTLKSWVDEAEQHDE"
     gene            51591..52622
                     /gene="galR"
                     /locus_tag="RHX21_001209"
     CDS             51591..52622
                     /gene="galR"
                     /locus_tag="RHX21_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator GalR"
                     /protein_id="HDV1986430.1"
                     /translation="MATIKDVARLAGVSVATVSRVINNSPKASEASRLAVHSAMESLS
                     YHPNANARALAQQTTETVGLIVGDVSDPFFGAMVKAVEQVAYHTGNFLLIGNGYHNEQ
                     KERQAIEQLIRHRCAALVVHAKMIPDADLASLMKQMPGMVLINRILPGFENRCIALDD
                     RYGAWLATRHLIQQGHTRIGYLCSNHSISDAEDRLQGYYDALAESGIAANDRLVTFGE
                     PDESGGEQAMTELLGRGRNFTAVACYNDSMAAGAMGVLNDNGIDVPGEISLIGFDDVL
                     VSRYVRPRLTTVRYPIVTMATQAAELALALADNRPLPEITNVFSPTLVRRHSVSTPSL
                     EASHHATSD"
     gene            complement(52629..53891)
                     /gene="lysA"
                     /locus_tag="RHX21_001210"
     CDS             complement(52629..53891)
                     /gene="lysA"
                     /locus_tag="RHX21_001210"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HDV1986431.1"
                     /translation="MPHSLFSTDTDLTAENLLRLPAEFGCPVWVYDAQIIRRQIAALK
                     QFDVVRFAQKACSNIHILRLMREQGVKVDSVSLGEIERALAAGYNPQTHPDDIVFTAD
                     VIDQATLERVSELQIPVNAGSVDMLDQLGQVSPGHRVWLRVNPGFGHGHSQKTNTGGE
                     NSKHGIWYTDLPAALDVIQRHHLQLVGIHMHIGSGVDYAHLEQVCGAMVRQVIEFGQD
                     LQAISAGGGLSVPYQQGEEAVDTEHYYGLWNAAREQIARHLGHPVKLEIEPGRFLVAQ
                     SGVLITQVRSVKQMGSRHFVLVDAGFNDLMRPAMYGSYHHISALAADGRSLEHAPTVE
                     TVVAGPLCESGDVFTQQEGGNVETRALPEVKAGDYLVLHDTGAYGASMSSNYNSRPLL
                     PEVLFDNGQARLIRRRQTIEELLALELL"
     gene            54013..54948
                     /gene="lysR"
                     /locus_tag="RHX21_001211"
     CDS             54013..54948
                     /gene="lysR"
                     /locus_tag="RHX21_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator LysR"
                     /protein_id="HDV1986432.1"
                     /translation="MAAVNLRHIEIFHAVMTAGSLTEAAHLLHTSQPTVSRELARFEK
                     VIGLKLFERVRGRLHPTVQGLRLFEEVQRSWYGLDRIVSAAESLREFRQGELSIACLP
                     VFSQSFLPQLLQPFLARYPDVSLNIVPQESPLLEEWLSAQRHDLGLTETLHTPAGTER
                     TELLSLDEVCVLPPGHPLAVKKVLTPDDFQGENYISLSRTDSYRQLLDQLFTEHQVKR
                     RMIVETHSAASVCAMVRAGVGVSVVNPLTALDYAASGLVVRRFSIAVPFTVSLIRPLH
                     RPSSALVQAFSEHLQAGLPKLVTSLDAILSSATTA"
     gene            complement(54935..55627)
                     /gene="ygeA"
                     /locus_tag="RHX21_001212"
     CDS             complement(54935..55627)
                     /gene="ygeA"
                     /locus_tag="RHX21_001212"
                     /EC_number="5.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HDV1986433.1"
                     /translation="MKTIGLLGGMSWESTIPYYRLINEGIKQRLGGLHSAQVLLHSVD
                     FHEIEECQRRGEWDKTGDILAEAALGLQRAGAEGIVLCTNTMHKVADAIESRCTLPFL
                     HIADATGRAITGAGMTRVALLGTRYTMEQDFYRGRLTEQFSINCLIPEADERAKINQI
                     IFEELCLGQFTEASRAYYAQVIARLAEQGAQGVIFGCTEIGLLVPEERSVLPVFDTAA
                     IHAEDAVAFMLS"
     gene            complement(55756..57174)
                     /gene="araE"
                     /locus_tag="RHX21_001213"
     CDS             complement(55756..57174)
                     /gene="araE"
                     /locus_tag="RHX21_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-proton symporter AraE"
                     /protein_id="HDV1986434.1"
                     /translation="MVTINTESALTPRSLRDTRRMNMFVSVAAAVAGLLFGLDIGVIA
                     GALPFITDHFVLTSRLQEWVVSSMMLGAAIGALFNGWLSFRLGRKYSLMAGAILFVLG
                     SIGSAFATSVEMLIAARVVLGIAVGIASYTAPLYLSEMASENVRGKMISMYQLMVTLG
                     IVLAFLSDTAFSYSGNWRAMLGVLALPAVLLIILVVFLPNSPRWLAEKGRHIEAEEVL
                     RMLRDTSEKAREELNEIRESLKLKQGGWALFKINRNVRRAVFLGMLLQAMQQFTGMNI
                     IMYYAPRIFKMAGFTTTEQQMIATLVVGLTFMFATFIAVFTVDKAGRKPALKIGFSVM
                     ALGTLVLGYCLMQFDNGTASSGLSWLSVGMTMMCIAGYAMSAAPVVWILCSEIQPLKC
                     RDFGITCSTTTNWVSNMIIGATFLTLLDSIGAAGTFWLYTALNIAFVGITFWLIPETK
                     NVTLEHIERKLMAGEKLRNIGV"
BASE COUNT        14001 a        15451 c        14172 g        13738 t
ORIGIN      
        1 ttaaatgaaa ataacgattc ttatcttttt aagtattcgc ttatttcctg gcgatctcct
       61 acagagtctg taagagatct ctcacaacca gatggggtat ttggattaca gaagaggctt
      121 aagttgatta aggaattccg caagatttga ggctaaatgc gtccgtttac gtgttcccag
      181 cgtctctttg cacacttcac cggagagatt acacaccgag atgacctcta actcttcttc
      241 cagcgtcgcg ataaatagcg tgggcggcag ttttagcctt ttctgagtca ccagatgacc
      301 aatcagattt tcctgcaccc gacggaagtc gtcttcactc caggtttgca gcaatgtcag
      361 tttgatatcg ccaaactgcg cgtgcatatc cccggcaaac tgagtcgtat aaaaggtatg
      421 aattgtgggt tgtatcacaa tatcaaaagc gcgttcaacc gcgtttacat tttgttcccc
      481 ggtaaacggc tggggttgcc agtatacggc atcttcggta gttgaaataa tgcacggtga
      541 aggaacaccg tacagttcct cacttaacgg ccagctttta tgctcttcat gccacgcatc
      601 gcagtagcgt gcagtaaaat ctttcagggc ttgtgcggtc aaatcgtcca ctaatttctc
      661 tcttcactta aaccagatac acttgtcgtt tagtttatct ggtttatgac ggtgaaacat
      721 gtcttcttat gcaaaccatc aggcacttgc gggcctgact cttggaaaat caaccgatta
      781 ccgggatacc tatgacgcca acctactgca aggcgttcca cgcagcctga atcgcgaccc
      841 gctgggtctg aaagcggata acctgccttt tcacggtacg gatatctgga cgctgtatga
      901 actttcctgg ctgaatgcga aaggtttgcc gcaggtcgct gtcggtcatg ttgaacttga
      961 ttacaccagc gtaaatctga ttgagtcgaa gagttttaag ctctatctca acagttttaa
     1021 ccagacgcgt tttaataact gggatgaggt gcgccagacg ctggagcgcg acttaagcac
     1081 ttgcgcccag ggtaaggtta gcgtggcgtt atatcgtctt gatgaactgg aaggccagcc
     1141 gataggtcat ttcaatggca cctgcattga tgaccaggat atcactatcg ataactatga
     1201 attcactact gactatctgg agaatgccac cagcggtgaa aaagtagtgg aagagacgct
     1261 tgtcagccac ctgctgaaat caaactgcct gatcacccat caaccagatt ggggttcgat
     1321 ccaaattcag tatcgtggac gccaaattga cagagaaaaa ctgctgcgtt acctggtctc
     1381 attccgtcat cacaacgagt tccacgaaca gtgcgtggaa cgcatcttta atgacctgtt
     1441 acgcttctgc cagccagaga aattaagcgt ttacgcacgt tatacccgtc gtggcggtct
     1501 ggacattaac ccgtggcgca gtaatagcga ttttgtccca tcgaccacaa gactggttcg
     1561 gcaataaatt ttttctcaat tttgcgtgct ggattcacgc agaaggttgt gaaaggtcat
     1621 caggcagggc tattgtaatc aaagggaatg acgatattcg tcccataagg agtttttctt
     1681 gattacacat attagcccgc ttggctccat ggatatgttg tcgcagctgg aagtggatat
     1741 gcttaaacgc accgccagca gcgacctcta tcaactgttt cgcaactgtt cacttgccgt
     1801 actgaactcc ggtagtttga ccgataacag caaagaattg ctgtctcgtt ttgaaaattt
     1861 cgatattaac gtcctgcgcc gtgaacgcgg cgtaaagctg gaactgatta atcccccgga
     1921 agaggctttt gtcgatgggc gaattattcg cgctttgcag gccaacttgt tcgcggttct
     1981 gcgagacatt ctcttcgttt acgggcaaat ccataatacc gttcgttttc ccaacctgaa
     2041 tctcgacaac tccgtccaca tcactaacct ggtcttttcc atcttgcgta acgctcgcgc
     2101 gctgcatgtg ggtgaagcgc caaatatggt ggtctgctgg ggcggtcact caattaacga
     2161 aaatgagtat ttgtatgccc gtcgcgtcgg aaaccagctg ggcctgcgtg agctgaatat
     2221 ctgcaccggc tgtggtccgg gagcgatgga agcgccgatg aaaggtgctg cggtcggaca
     2281 cgcgcagcag cgttacaaag acagtcgttt tattggtatg acagagccgt cgattatcgc
     2341 cgctgaaccg cctaacccgc tggtcaacga attgatcatc atgccggata tcgaaaaacg
     2401 tctggaagcg tttgtccgta tcgctcacgg catcattatc ttccctggcg gtgtgggtac
     2461 ggcagaagag ttgctgtatt tgctgggaat tttaatgaac ccggccaaca aagatcaggt
     2521 tttaccattg atcctcaccg gcccgaaaga gagcgccgac tacttccgcg tactggacga
     2581 gtttgtcgta catacgctgg gcgaaaacgc gcgccgccat taccgcatca tcattgatga
     2641 cgccgctgaa gtcgctcgtc agatgaaaaa atcgatgccg ctggtgaaag aaaatcgccg
     2701 cgacactggt gacgcttaca gctttaactg gtcaatgcgc attgcaccag atttgcaaat
     2761 gccgtttgag ccgtctcacg agaatatggc taatctgaag ctttacccgg atcaacctgt
     2821 tgaagtgctg gctgccgacc tgcgccgtgc gttctccggt attgtggcgg gtaacgtaaa
     2881 agaagtcggt attcgcgcca ttgaagagtt tggtccttac aaaatcaacg gcgataaaga
     2941 gattatgcgt cgtatggacg acctgctaca gggttttgtt gcccagcatc gtatgaagtt
     3001 gccaggctca gcctacatcc cttgctacga aatctgcacg taatctcccc tcccccggtg
     3061 acgtttgttg ccgggttttc tcgtttttgg tcacttactc atcaactcat ttcatttgtt
     3121 atatgaatgt ttcttaccac cctcacgcga caaatatcat cacagttaat atgtcataca
     3181 atttatattg caacgcaaac gtttccctat tttcataaac cgtattttat cgctatgaaa
     3241 aagaaattat cgccatgatt aactaaaagt attgattttt tcagttcaac ctacatatat
     3301 tgcgcgcccc ggaagaagtc agatgtcgtt taatgggcaa atattgccct taaattctct
     3361 tttacttttg atttacagag taaagcgttg ggataatcta tcttccaagt agattattgt
     3421 atttgagatc aagatcactg atagatacat aacttgtgtg tatctttccg ccctcaaatt
     3481 attacggcgg taaatgatta agccatcgcc gatagacaga tttcattttt acggtcaggc
     3541 accttcccgg gctgaactgg ctaaaagctg aattatttgc attcctccag gagaaataga
     3601 tggaaacgac tcaaaccagc acgattgcgt cgaaagactc tcgtagtgcc tggcgcaaga
     3661 cagacaccat gtggatgctg ggcctttacg gcacggcaat cggcgcgggc gtgctgttcc
     3721 tgccaatcaa cgccggtgtt ggcggtatga tcccgctgat catcatggct atccttgcgt
     3781 tcccgatgac gttttttgct caccgcggcc tgactcgctt cgtactgtct ggtaaaaacc
     3841 cgggcgaaga catcaccgag gttgtagaag aacactttgg tattggcgca ggtaaactga
     3901 ttaccctgct ctatttcttc gctatctacc cgatcctgct ggtttatagc gtagcaatca
     3961 ccaatacagt tgaaagcttc atgtctcacc agctgggtat gacaccaccg ccgcgtgcga
     4021 ttctgtcgct gatcctgatc gtgggtatga tgaccatcgt tcgcttcggt gagcagatga
     4081 tcgttaaagc gatgagtatt ctggtattcc cgtttgttgg cgtactgatg ctgctggctc
     4141 tgtacctgat cccgcagtgg aacggcgcag cactggaaac gctgtctctg gacactgcat
     4201 ctgcaaccgg gaacggtctg tggatgaccc tgtggctggc aattccggta atggtgttct
     4261 cgttcaacca ctctccgatc atctcttctt tcgccgttgc gaagcgtgaa gagtacggcg
     4321 atatggcaga acagaaatgc tcgaagatcc ttgcattcgc acacatcatg atggtgctga
     4381 ccgtaatgtt cttcgtcttc agctgcgtac tgagcctgac tccggcagac ctggctgcgg
     4441 ctaaagagca gaacatctcg attctgtctt acctggctaa ccactttaac gcaccggtta
     4501 tcgcgtggat ggctccgatt atcgcgatta tcgctatcac caaatccttc ctcggccact
     4561 acctgggcgc acgtgaaggc ttcaacggta tggtgattaa atctctgcgt ggtaaaggta
     4621 agtctatcga aatcaacaag ctgaaccgta tcactgcgct gttcatgctg gtaacgacct
     4681 ggattgttgc caccctgaac ccgagcatcc tgggtatgat tgaaaccctg ggcggcccaa
     4741 tcatcgcgat gatcctgttc ctgatgccga tgtacgcaat tcagaaagta ccggcaatgc
     4801 gtaagtacag cggtcacatc agcaacgtat tcgttgtcgt gatgggtctg attgcaatct
     4861 ccgcaatctt ctactctctg ttcagctaag tcctttcgcg ccgctttcgg gcggcgcttc
     4921 ctccgtttta acgcgatgta tttcctatga ttagcgtatt cgatattttc aaaatcggca
     4981 ttggcccttc cagttctcat accgttggac caatgaaagc gggtaaacaa tttaccgacg
     5041 atctgattgc ccgtaatctg cttaaagacg tgacccgcgt ggtggttgac gtgtacggct
     5101 cgctctctct gaccggtaaa ggccaccaca ctgatatcgc cattattatg ggcctggcgg
     5161 gtaacctgcc ggataccgtg gatatcgatt ccatccctgg ttttattcag gatgtgaata
     5221 ctcatggtcg cctgatgctg gcaaacggtc agcatgaagt ggagttcccg gttgatcagt
     5281 gcatgaactt ccatgcagac aacctttctc tgcatgaaaa cggtatgcgc attaccgcgc
     5341 tggcgggcga taaagtcgtt tacagccaga cttactactc tattggcggt ggctttatcg
     5401 ttgatgaaga gcattttggc cagcagaata gcgcaccggt tgaagttcct tatccgtaca
     5461 gttcagcagc cgatctgcaa aaacattgtc aggaaaccgg gctgtcactc tctggcctga
     5521 tgatgaaaaa tgagctggcg ctgcacagca aagaagagct ggaacagcac ctggcgaacg
     5581 tatgggaagt catgcgtggc ggtattgagc gcggtatttc caccgaaggc gtgttgcctg
     5641 gcaaactgcg cgttccacgc cgtgctgcgg cactacgccg gatgctggtc agccaggata
     5701 aaaccaccac tgacccgatg gcggttgttg actggatcaa catgtttgca ctggcagtga
     5761 acgaagagaa cgctgctggc ggacgcgtgg tgactgcgcc gactaacggt gcgtgcggga
     5821 ttatcccggc agtgctggcg tactacgaca agtttatccg cgaagtgaac gctaactcac
     5881 tggctcgtta cctgctggta gccagtgcca ttggttctct ttataagatg aacgcgtcaa
     5941 tttctggtgc tgaagtcggc tgccagggtg aagttggtgt ggcgtgctca atggcggcgg
     6001 ctggtctggc agaactgtta ggtgcaagcc cggcgcaggt gtgcatcgcg gcggaaatcg
     6061 ccatggagca caacctcggt ctgacgtgtg acccggtcgc cggacaggtc caggtgccat
     6121 gcatcgagcg taacgccatt gcggcagtaa aagcggtgaa cgccgcacgt atggcgctac
     6181 gccgtaccag cgagccgcgc gtctgcctcg ataaagttat cgaaaccatg tacgaaacag
     6241 gtaaagatat gaacgccaag taccgcgaaa cctctcgcgg cggcctggca atgaagatcg
     6301 ttgcctgcga ttaatcgctc tccagaggcc tcgttttgcg aggcctcttc ccgatttctc
     6361 atccagccgt agcctgttcc ggcatcgaat gttaccctta tcgcctgatc tttaaggggg
     6421 ttatcgtggc tgttcatttg cttattgtcg atgcactgaa tcttattcgt cgcattcatg
     6481 ccgttcaggg atcgccctgt gtcgaaacct gccagcatgc gctcgatcag ctcattatgc
     6541 acagccagcc aacccacgcg gtcgccgttt ttgatgatga aaaccgcagt agcggctggc
     6601 gtcatcagcg tttaccagat tacaaagcgg gtcgaccgcc aatgccggaa gagttgcacg
     6661 acgagatgcc tgcattacgc gccgcctttg agcaacgcgg cgtcccgtgc tggtcaacca
     6721 gcggcaacga agccgatgac ttagccgcca cgctggcggt caaagtgaca caggccgggc
     6781 atcaggcaac gattgtttcg acagataaag gctactgtca gttactttca ccgacattac
     6841 gtattcgtga ttacttccag aaacgttggc tggatgcgcc atttatcgat aaagaatttg
     6901 gcgttcaacc gcagcagttg cccgattact ggggacttgc ggggatcagc agttcaaagg
     6961 taccgggtgt tgcgggaatc ggaccaaaaa gcgccacgca gctgctggtc gagtttcaga
     7021 gtctggaagg gatatatgag aatctggatg cggttgccga aaagtggcgc aaaaaattag
     7081 aaacccataa agagatggcg tttctgtgcc gcgatattgc ccgcttacaa accgatttgc
     7141 atatcgacgg caatttacag caattgcggt tggtacggta acggcgagcc ggatacgccg
     7201 caaacgtcgt atccggcatt atcacatcag cgcatttacc aggcggtatg gtaaagctct
     7261 acaatatcct caagcgttgc ttcacgcggg ttgccaccgg tacaaacatc atccagtgcc
     7321 gcctgcgcca gtgccggaat gtcttccttg cgtaccccaa catcacgcaa atgtggcgga
     7381 ataccgacat cacggttgag agcaaacacc gcttcaacag cggcattacg cgcctcttcc
     7441 aggctcatac cttccacttt cacgcccata acgcgcgcga tatcgcggta cttctcaccg
     7501 gtaaagtcag cgttatagcg catgacatgc ggtagcagga tggcgtttgc aacaccgtgt
     7561 ggagtgttat aaaacgcgcc cagtggatgc gccataccat gcaccaaccc taacccaaca
     7621 ttcgagaagc ccatacccgc aacatactgc ccgagcgcca tttcttctcc ggcatcctta
     7681 tcaccagcaa ccgatcctcg cagcgcccca gcaatgattt caatcgcttt aatgtgcagt
     7741 gcatcggtta gcgcccacgc gccacgggta atatacccct caatagcatg agtgagcgca
     7801 tcgacacccg tcgcagcttt cagcgctgga ggcataccat ccatcatgtc agcgtcaata
     7861 aacgccacct gcgggatatc atgcggatca acgcaaacaa acttgcgccg tttttcttcg
     7921 tcagtgatca cgtagttaat ggtcacttct gccgcagtgc ctgctgtggt ggggattgcc
     7981 agaatcggta cactggtttt attggtcggg gaaagtcctt ccaggctacg cacatcggca
     8041 aactccgggt tgttgctgat aatgccaatc gctttacaag tatcctgtgg agaaccacca
     8101 ccaatagcga tcaggtaatc cgcgccgcta ttctggaata caccgagccc ttctttgacg
     8161 acagtaattg ttgggttggg cactacgccg tcgtaaatcg cccatgccag ccctgcagca
     8221 tccatcttat cggtcacttt cgccaccacg ccgcattgca ccagcgtttt atcggtgacg
     8281 atcagcgcct tctgataacc acggcgtttc acctcatcgg ttaaagcccc aacagcaccc
     8341 cgaccaaacc atgccgtttc gttcagaatc attctgttag ccatcatcct tctccttgtt
     8401 gctttacgaa attactcttc aattcgtaac ccataggttt tgaatttctc cagcactacg
     8461 gcaatctctt catcgctcag cactggcacc gggtccgtaa tcgccagggt cgtcaggtaa
     8521 agttgcgcca gcacttcaac ttcatgcgcc agccataacg ctttttccag attcacctca
     8581 caagcgataa gcccatgatg ttgtaacaaa gttgccttac gatttttgag agcctgcgca
     8641 acatgttcag aaagttcacg tgttccaaag gtcgcataag gcgcgcaagg aatagaatta
     8701 ccgccagccg ccgcaatcat gtagtgaata gcggggatcg atcggttaag aatggaaact
     8761 gccgtgcaat gaacggcatg attgtgaaca accgcgttgg catccggtct gctttgatag
     8821 gccgccatat ggaaacgcca ttcgcttgag gggagctttc cttcctcatg tttaccgttg
     8881 ccatcaataa agacaatatg cgactccgtc agtttttcat atggaatgcc tgtaggcgta
     8941 atcagcatcc catcctgata acgtacactg acgttccccg ctgtcccctg gttcagtccc
     9001 aggcgggtca tttccaggca agtgtcaata atctgacgag caagtttatt tcgttccatt
     9061 agctacctct ctctgattca aaacagggca ataatgttgt tcctttcaca ctattgaatt
     9121 agccgtttaa ttacccacca tcttcttcct gattaaccag aaagaaattc acaagcttat
     9181 attttgtgac ctggttcaac taatcacagt aaataactgc aagttctctt tttataaccc
     9241 cattaaaaat gaccgctctt aaaaatattt atcaaaacgg tcatttttct attcactcaa
     9301 gccaggaatg cccgttttcg gcataaacaa ttaatacggt catctggttt gtgtttttta
     9361 tgatttattt tctgaaacgg gcatgaaatt tcgattatta aagtgatggt agtcacataa
     9421 agtcaccttc cagctaataa gtgtgaccgc cgtcatatta cagagcgttt tttatttgaa
     9481 aatgaatcca tgagttcatt tcagacaggc aaatattcac tgatatgaag cccgaactcg
     9541 ctggttttgc acttttgaaa acataaccga ttacgtgctt aagcttctga acctaagagg
     9601 atgctatggg aaacacatca atacaaacgc agagttaccg tgcggtagat aaagatgcag
     9661 ggcaaagcag aagttacatt attccattcg cgctgctgtg ctcactgttt tttctttggg
     9721 cggtagccaa taaccttaac gacattttat tacctcaatt ccagcaggct tttacgctga
     9781 caaatttcca ggctggcctg atccaatcgg ccttttactt tggttatttc attatcccaa
     9841 tccctgctgg gatattgatg aaaaaactca gttataaagc agggattatt accggattat
     9901 ttttatatgc cttgggcgct gcattattct ggcccgctgc agaaataatg aactacacct
     9961 tatttttagt tggcctattt attattgcag ccggattagg ttgtctggaa actgccgcaa
    10021 acccttttgt tacggtatta gggccggaaa gcagtggtca ctttcgctta aatcttgcgc
    10081 aaacatttaa ctcgtttggc gcaattatcg cggttgtctt tgggcaaagt cttattttgt
    10141 ctaacgtgcc acatcaatcg caagacgttc tcgataaaat gtctccagag caattgagtg
    10201 cgtataaaca cagcctggta ttatcggtac agacacctta tatgatcatc gtggctatcg
    10261 tgttactggt cgccctgctg atcatgctga cgaaattccc ggcattgcag agtgataatc
    10321 acagtgacgc caaacaagga tcgttctccg catcgctttc tcgtctggcg cgtattcgtc
    10381 actggcgctg ggcggtatta gcgcaattct gctacgttgg cgcacaaacg gcctgctgga
    10441 gctatttgat tcgctacgct gtagaagaaa ttccaggtat gactgcaggc tttgccgcta
    10501 actatttaac cggaaccatg gtgtgcttct ttattggtcg tttcaccggt acctggctca
    10561 tcagtcgctt cgcaccacac aaagtcctgg ccgcctacgc attaatcgct atggcactgt
    10621 gcctgatctc agccttcgct ggcggtcatg tgggcttaat agccctgact ttatgcagcg
    10681 cctttatgtc gattcagtac ccaacaatct tctcgctggg cattaagaat ctcggccagg
    10741 acaccaaata cggttcgtcc ttcatcgtta tgaccatcat tggcggcggt attgtcactc
    10801 cggtcatggg ttttgtcagt gacgcggcgg gcaacatccc cactgctgaa ctgatccccg
    10861 cactctgctt cgcggtcatc tttatctttg cccgtttccg ctctcaaacg gcaactaact
    10921 gaacatattt tccgaataaa gtgaggaatc tgtaatgaaa aaaatcagct taccgaaaat
    10981 tggtatccgc ccggttattg acggtcgtcg catgggtgtt cgtgagtcgc ttgaagaaca
    11041 aacaatgaat atggcgaaag ctacggccgc actgctgacc gagaaactgc gccatgcctg
    11101 cggagctgcc gtcgagtgtg tcatttccga tacctgtatc gcgggtatgg ctgaagccgc
    11161 tgcttgcgaa gaaaaattca gcagtcagaa tgtaggcctc accattacgg taacgccttg
    11221 ctggtgctat ggcagtgaaa ccatcgacat ggatccaacc cgcccgaaag ccatttgggg
    11281 ctttaacggc actgaacgtc ccggcgctgt ttacctggca gcggctctgg cagctcacag
    11341 ccagaaaggc atcccggcat tctccattta cggtcatgac gttcaggatg ccgatgacac
    11401 atcgattcct gccgatgttg aagaaaaact gctgcgcttt gcccgcgccg gtttggccgt
    11461 cgccagcatg aaaggtaaaa gctatctgtc gctgggcggc gtttcgatgg gtatcgccgg
    11521 ttctattgtt gatcacaact tctttgaatc ctggctggga atgaaagtcc aggcggtgga
    11581 tatgaccgaa ctgcgtcgcc gtatcgatca gaagatttac gacgaagccg aactggaaat
    11641 ggcactgacc tgggctgata aaaacttccg ctatggcgaa gatgaaaata acaaacagta
    11701 tcaacgcaat gccgagcaaa gccgcgcagt tctgcgcgaa agtttactga tggcgatgtg
    11761 tatccgcgac atgatgcaag gcaacagcaa actggccgat attggtcgcg tggaagaatc
    11821 acttggctac aacgccatcg ctgcgggctt ccaggggcaa cgtcactgga ccgatcaata
    11881 tcccaatggt gacaccgccg aagcgatcct taacagttca tttgactgga atggcgtgcg
    11941 cgaacccttt gtcgtggcga ccgaaaacga cagtcttaac ggcgtggcaa tgctaatggg
    12001 tcaccagctc accggcaccg ctcaggtatt tgccgatgtg cgtacctact ggtcaccaga
    12061 agcaattgag cgtgtaacgg ggcataaact cgatggactg gcagaacacg gcatcatcca
    12121 tttgatcaac tccggttctg ctgcgctgga cggttcctgt aaacaacgcg acagcgaagg
    12181 taacccgacg atgaagccgc actgggaaat ctctcagcaa gaggctgacg cttgcctcgc
    12241 cgctaccgaa tggtgcccgg cgatccacga atacttccgt ggcggcggtt actcttcccg
    12301 cttccttacc gaaggcggcg tcccgttcac catgacccgt gtcaacatca tcaaaggcct
    12361 gggaccggta ctgcaaatcg cggaaggctg gagcgtggaa ttgccgaagg atgtgcatga
    12421 catcctcaac aaacgcacca actcaacctg gccaaccacc tggtttgcac cgcgcctcac
    12481 cggtaaaggg ccgtttacgg atgtgtactc ggtaatggcg aactggggcg ctaaccatgg
    12541 ggttctgacc atcggccacg ttggcgcaga ctttatcact ctcgcctcca tgctgcgtat
    12601 cccggtatgt atgcacaacg ttgaagagac caaagtgtat cgtccttctg cctgggctgc
    12661 gcacggcatg gatattgaag gccaggatta ccgcgcttgc cagaactacg gcccgttgta
    12721 caagcgttaa tacattactc cctgatgtga tgcccggtcg ctccggctac cgggcctgaa
    12781 caagcaagag tggttagccg gataagcaat gttatccggc tatattgcag gagcgattat
    12841 gaaacaagaa gttatcctgg tactcgactg tggcgcgacc aatgtcaggg ccatcgcggt
    12901 taatcggcag ggaaaaattg ttgcccgcgc ctcaacgcct aatgccagcg atatcgcgat
    12961 ggaaaacaac acctggcacc agtggtcttt agacgccatt ttgcaacgct ttgctgattg
    13021 ctgtcggcaa atcaatagtg aactgactga atgccacatc cgcggtatcg ccgtcaccac
    13081 ctttggtgtg gatggcgctc tggtagataa gcaaggcaat ctgctctatc cgatcattag
    13141 ctggaaatgt ccgcgaacag cagcggttat ggacaatatt gaacagttga tctccgcaca
    13201 gcggttgcag gctatttctg gcgtcggagc ctttagtttc aatacgttat ataagttggt
    13261 gtggttgaaa gaaaatcatc cacaactgct ggaacgcgcg cacgcctggc tctttatttc
    13321 gtcgctgatt aaccaccgtt taaccggcga attcactact gatatcacga tggccggaac
    13381 cagccagatg ctggatatcc agcaacgcga tttcagtccg caaattttac aagccaccgg
    13441 tattccacgc cgactcttcc ctcgtctggt ggaagcgggt gaacagattg gtacgctaca
    13501 gaacagcgcc gcagcaatgc tcggcttacc cgttggcata ccggtgattt ccgcaggtca
    13561 cgatacccag ttcgcccttt ttggcgctgg tgccgaccaa aatgaacccg tgctctcttc
    13621 cggtacatgg gaaattttaa tggtccgtag cgcccaggtt gatacttcgc tgttaagtca
    13681 gtacgccggt tccacctgcg aactggatag ccaggcaggg ttgtataacc caggtatgca
    13741 atggctggca tccggcgtgc tggaatgggt gagaaaactg ttctggacgg ctgaaacacc
    13801 ctggcaaatg ttgattgaag aagctcgtct gatcgcgcct ggcgcggatg gcgtaaaaat
    13861 gcagtgtgat ttattgtcgt gtcagaacgc tggctggcaa ggagtgacgc ttaataccac
    13921 gcgggggcat ttctatcgcg cggcgctgga agggttaact gcgcaattac agcgcaatct
    13981 acagatgctg gaaaaaatcg ggcactttaa ggcctctgaa ttattgttag tcggtggagg
    14041 aagtcgcaac acattgtgga atcagattaa agccaatatg cttgatattc cggtaaaagt
    14101 tctcgacgat gccgaaacga ccgtcgcagg agctgcgctg ttcggttggt atggcgtagg
    14161 ggaattcaac agcccggaag aagcccgtgc acagattcat tatcagtacc gttatttcta
    14221 cccgcaaact gaacctgaat ttatagagga agtgtgaaat gctgaaaaca atttcgccgt
    14281 taatttctcc cgaactattg aaagtgctgg cagagatggg acatggagat gaaattattt
    14341 tttccgatgc tcactttccc gcccattcga tgggaccgca ggtgatccgc gctgatggcc
    14401 tgttggtgag cgacttgctc caggcgatta tcccgttatt tgagctggac agttatgcac
    14461 cgccgctggt gatgatggca gcggtagaag gtgacactct cgatcctgaa gtagaacgac
    14521 gttaccgtaa tgcgctttca ctacaagccc cgtgtcctga catcatccgc atcaatcgtt
    14581 ttgcgtttta tgaacgggcg caaaaagcct ttgcgatcgt tatcacaggc gaacgagcga
    14641 agtacgggaa tattctttta aaaaaagggg taacaccgta atctcatacc ggtacgcccg
    14701 catgacgcgg gcggttatcg aatgatgggg tgaaaaatat gaaagcggca cgccagcaag
    14761 cgatagtcga cctgctgctg aaccatacca gcctgaccac ggaagctctc tctgaacagc
    14821 taaaggtcag taaagaaacc attcgtcgcg atctcaatga attacagacg cagggtaaaa
    14881 ttctgcgcaa tcatggacgc gctaaatata tccaccgtca aaatcaagac agtggcgatc
    14941 cctttcacat ccggctgaaa agccattatg cgcataaagc agatatcgcg cgcgaggcgc
    15001 tcgcgtggat tgaagaaggg atggtgatag ccttagacgc cagttcaact tgctggtatc
    15061 tggcacgcca gttgcctgac atcaacattc aggtcttcac caatagccat ccgatttgcc
    15121 atgaactcgg taaacgcgaa cgcattcaac tgatcagttc cggcggcaca cttgagcgca
    15181 aatatggctg ttacgtcaat ccctcgctga tttcccaact taaatcgctg gaaatcgatc
    15241 tgtttatttt ttcttgtgaa gggatcgata gcagcggcgc attgtgggac tccaatgcca
    15301 tcaacgctga ttacaaatcg atgctattaa aacgtgccgc gcaatcgttg ttattgattg
    15361 ataaaagtaa atttaatcgt tcaggggaag cccgcatcgg gcatctggat gaggtaacgc
    15421 acattatttc tgatgagcgc caggttgcaa cttctttggt aacagcctga cggaaagggt
    15481 agcaggccgg agacgacgcc ccggccttgc ctgttatcgc tcgtcgcgac gaccacccac
    15541 cgcagcccag atgcggcgga cgtgcaccgt cacttcttcg cgatcgtgat acaactgccg
    15601 cgcctgaatc tgagcattta tgccatgttc atcaagctgt gcctgaatat acgccagatt
    15661 gtgtgacact tcttcgtagc gttttttcat cggcagtttg aggttgaaaa tggtttcacg
    15721 gcaccagcca ttaaccagcc actgcgccat caatgccgca actttcgccg gtttttcaac
    15781 catatcgcat accatccagg agatattgct gcgcgtcgga cggaatttga aaccgtcttc
    15841 ccgcagccac gtcacctgtc cggtatccat cagactttgc gccatcgggc cgttgtcgac
    15901 ggaataaacc cacatgttgc gcttcaccag ttggtaggtc cagccgccag ggcaagcgcc
    15961 taaatccacc gcccacatcc cgttcgccag gcgttcatcc cactcatccg caggaataaa
    16021 cacatgaaat gcctcttcca gtttgagcgt ggaacgactc ggcgcatctg ccggaaattt
    16081 caggcgcgga atgcccatat agaacggcga attattgttg ctgtatgagt aaccggtata
    16141 gcagcagcct ggtgcaataa agaatacatg cacaaccgga cgcttcggcg tttcatagtt
    16201 cgccagcacc ccggcatcgc gcaaggcagc gcgtagcgga acagtaaatt tacggcagaa
    16261 tttcagtaac tctttgcttt cgttggtatc ggcaacttca acacgcagtt caccgccctt
    16321 ctctactacg ccctgtaaca tgccgacaat gggggtaata cgatcttctg gcggcaaatg
    16381 ctgcaggagt tcccccacca caaaccactg gcgggcaaaa attaatgaac tgaacggcag
    16441 ctcacggatt aacttatcgc catcatcagg ttgataacat tcataaatga cataacccgc
    16501 attctctttc acgcgggcaa aaccgaaaat ttcccgctgg ccggctttat cggtaatttc
    16561 tgcggcgcac tctttttcaa agcccggacg gcacagcaat acaaccttat tcatgactta
    16621 cgcccttgcg ctttaaacgg atagcaccaa ctaacattaa cgcccagccc gcgaggaagc
    16681 tcacgccgcc aaccggagtg acaaacgccc acaaacgcag atgggacagc gccaggcaat
    16741 aaaggctgcc gctgaacaac accgtgccta acgcgaggaa aacgctactc cagtaaaacc
    16801 agatactgat gcgacgctgc attgccaccg ccagacctaa gatcgccagc gtatgaaacg
    16861 cctggtattc gaggccggtc tggatccagc ccatctcaac ggcccccatg gttttactta
    16921 acacatgcgc gccaaaagcg cccagagcca caaaaatgaa gccgctaatg gcggcgaaaa
    16981 tcagcatgaa acggctggtc atggtcgtac cctacgtaaa ttattgttca taacgaaagc
    17041 ggaatttttc ttgttcagca gcggctttcg ccaggatcca ttggcgaaag gcggctattt
    17101 tacccagttc agcctggctg tcatgacaaa ccagataaaa agcgttttta ctgaccagaa
    17161 catcattaaa cgggcaaaca agacgtccgg cctcgatttc agattgcgcc atcacgttat
    17221 ttgccaacgc cactccctgc ccgtgaatag ccgcttgcag caccatggcg ctatgactaa
    17281 aaattggccc ttgctgaacg ttgatatgat ttaaccccaa ctgtcgggta tatgtctgcc
    17341 agtcacggcg tgacgcatca tgtaataacg tatgtttagc cagatcttcc ggggtcttca
    17401 agggtttttc gcctgtcagc agtagcggcg aacacaccgg caataaatat tcggcgtaca
    17461 gtttttccac ccgtagcccc ggccagttgc cccgaccata aaatatcgcc acatcaacat
    17521 catccgccag cttatcttcc tgacgatcaa ccgcctggat tcgaacgtca attcccggat
    17581 aagctgaatt aaagctggaa agtcgcggaa ccaaccaatg aatggcgaaa ctggggagta
    17641 aactgaccgt caacgccccc ttggcgctac gggcctggag tttacgcgtc gcttcggtta
    17701 attgcgaaaa tatctctttg atatcgagga aatagctttg cccttcctcg gtcagcagga
    17761 gtgaacgatt acggcggcgg aacagtttta gccccaaaaa atcctcaaga gacttgattt
    17821 gatgacttac tgcggcctgg gtcacaaaaa gctcttctgc tgcgcgagtg aaacttaaat
    17881 ggcgtgctgc ggcatcaaaa actcgtaagg catttagcgg tggtaatcgt ttagacatgg
    17941 cttttaaact ttgatgttaa atgaatttaa caattagatc acactgtgta acctattagt
    18001 ttttttaatc tgagccatta taaattgtcc gttgagcttc taccagcaaa tacctatagt
    18061 ggcggcactt cctgagccgg aacgaaaagt tttatcggaa tgcgtgttct ggtgaacttt
    18121 tggcttacgg ttgtgatgtt gtgttgttgt gtttgcaatt ggtctgcgat tcagaccatg
    18181 gtagcaaagc tacctttttt cacttcctgt acatttaccc tgtctgtcca tagtgattaa
    18241 tgtagcaccg cctaattgcg gtgctttttt ttaccttgcg atcgcgaatt actgatccag
    18301 ttcgaccatc tctttcacgt cagtacggtt gatctgctgt ttgttgccat tagcgtcttt
    18361 atacgaaatc ataccggtat cgttatcagt ctgtggtttg ccgtcagaga cgatggtacg
    18421 tccgtcattg gtgtgcatca catagttcga accggaacag gcgctcaggg caaaagtcag
    18481 catacaggca gaaataattg cggcagtctt tttcatcatc ttctccttaa agcgattaat
    18541 aaatcttaat agtattgatt aacaggctaa aattaacgcc taacactatt cagcatatgt
    18601 tacttgcgcg gcttcgccag gatatccaga taattctgat ggttagcact ctccttgtat
    18661 caaagtgaat tttgcgtcac gatcggtgca tcaagccgag gagtaccatg aacgttttta
    18721 atcccgcgca gtttcgcgcc cagtttcccg cactacagga tgcgggcgtc tatctcgaca
    18781 gcgccgcgac cgcgcttaaa cctgaagccg tggttgaagc cacccaacag ttttacagtc
    18841 tgagcgccgg aaacgtccat cgcagccagt ttgccgaagc ccaacgcctg accgcgcgtt
    18901 atgaagctgc acgagagaaa gtggcgcaat tactgaatgc accggatgat aaaactatcg
    18961 tctggacgcg cggcaccact gaatccatca acatggtggc acaatgctat gcgcgtccgc
    19021 gtctgcaacc gggcgatgag attattgtca gcgtggcaga acaccacgcc aacctcgtcc
    19081 cctggctgat ggtcgcccaa caaactggag ccaaagtggt gaaattgccg cttaatgcgc
    19141 agcgactgcc ggatgtcgat ttgttgccag aactgattac tccccgtagt cggattctgg
    19201 cgttgggtca gatgtcgaac gttactggcg gttgcccgga tctggcgcga gcgattacct
    19261 ttgctcattc agccgggatg gtggtgatgg ttgatggtgc tcagggggca gtgcatttcc
    19321 ccgcggatgt tcagcaactg gatattgatt tctatgcttt ttcaggtcac aaactgtatg
    19381 gcccgacagg tatcggcgtg ctgtatggta aatcagaact gctggaggcg atgtcgccct
    19441 ggctgggcgg cggcaaaatg gttcacgaag tgagttttga cggcttcacg actcaatctg
    19501 cgccgtggaa actggaagct ggaacgccaa atgtcgctgg tgtcatagga ttaagcgcgg
    19561 cgctggaatg gctggcagat tacgatatca accaggccga aagctggagc cgtagcttag
    19621 caacgctggc ggaagatgcg ctggcgaaac gtcccggctt tcgttcattc cgctgccagg
    19681 attccagcct gctggccttt gattttgctg gcgttcatca tagcgatatg gtgacgctgc
    19741 tggcggagta cggtattgcc ctgcgggccg ggcagcattg cgctcagccg ctactggcag
    19801 aattaggcgt aaccggcaca ctgcgcgcct cttttgcgcc atataataca aagagtgatg
    19861 tggatgcgct ggtgaatgcc gttgaccgcg cgctggaatt attggtggat taatgacaaa
    19921 cccgcaattc gccggacatc cgttcggcac aaccgtaacc gcagaaacgt tacgcaatac
    19981 cttcgcaccg ttgtcgcaat gggaagataa atatcgccag ttgatcatgc tggggaaaca
    20041 gcttccggct ttgccagacg agttaaaagc gcaggctaaa gagattgccg gatgcgaaaa
    20101 ccgcgtctgg ctgggatata ccgtgactga aaacggtaaa atgcacttct ttggcgacag
    20161 cgaagggcgc attgtgcgcg gcctgttggc ggtgttgttg actgccgttg aggggaaaac
    20221 cgtcgccgaa ttgcaggcac agtcgccgct ggcattgttt gatgagctgg gattgcgtgc
    20281 acagcttagc gcctcacgca gccaggggtt gaatgcgtta agcgaggcga ttatcgctgc
    20341 ggcgaagcag gtttaagcac agaaccaggt cggataagac gttcgcgtcg catccgacct
    20401 gattgtttaa ccctgacgcg ccgctttcgc catcatcttc ttcagcgcat gagaaaccgc
    20461 aacaaaccca aaggtggcgg tcaccatcgt tgccgcgcca aatccagatg cacaatccat
    20521 ccgcttcggc ccttctgccg tggctttcat cgcacacaca gtaccgtctg actgcgggta
    20581 caccagcgct tcagtagaaa acacgcaatc gacgccgagc ttacctttac tgtttttcac
    20641 tacgccaaaa tcgcttttca ggcgctcgcg caacttcgcc gccagcggat cctgaatcgt
    20701 tttcgccaga tcggtaacct gaatctgcgt cgggtcaatc tgcccacccg cgccaccggt
    20761 cgtgaccagc gggattttat tgcgccgaca ataagcaatc agcgccgctt tgggccgtac
    20821 actatcaatg gcatcaatca cgtacgaata acccacgctc atatactgcg ctacgttatc
    20881 cggcgtcacg aaatcatcca ccaccgttac acggcactcc gggttaatct ggcgaatacg
    20941 ctccgccatg acttccgctt ttgccagccc gacgttatcg cgcagagcgt gaatttgccg
    21001 attggtattg gtgacgcaca catcatccat atcgataagc gtgattgcgc caatccccgt
    21061 gcgcgccagc gcttccgccg cccaggaacc gacaccaccg ataccaacca cacaaatatg
    21121 cgcgtcagca aacagttgca acgctttttc accatacaga cgcgctgtgc caccaaaacg
    21181 ctgacgccat gcatcactaa ttaccacaga catagcacct cagaattaaa aagggtgagg
    21241 ttatccctca ccctggcgta tccgtaaaaa cggtatacag aataacacat cagccgctaa
    21301 agacgttacc tgcgcccggg gcggttttca gcacccagac acgtccatag tggttgtacc
    21361 aacctgcgcg atgtccggct tccggcccga tcccttgata gatatcgaag tgttggcctt
    21421 tgattgcgcc accgacatcc agcgccacca tcagacgcaa ttcgtactga ccgttaaatt
    21481 tgccgttatt atccagcagc ggcacttctg ccagcaaggt agtacctggc ggaataattg
    21541 aacgatcgga ggcaacagaa gcacggccaa ccagcggcac cgcacttgcc cctttcaccg
    21601 gtgcaaaaga ttgcggttta aagaaaacga aagacgggtt ctgttccagc agctcgcgaa
    21661 cctcggcttc actgtgtgtt tcgccccaat gacgaatcgc ctgcatcgac atatcttctt
    21721 ttttcacttc gccacggtcg atcagcacct taccaatgct gcgataggca tgaccgtttt
    21781 tccctgcata gctgaaaaag ttaagcggac tgccatcacc aaagtcgata tacccgctac
    21841 cctgcacatc cataatgaag ttatccatca gggagttgct gtaagcgaga atatatttat
    21901 cactcagcgc ccctgcgtag atctccgcac gagacggcag acgaccacgt tttggcggca
    21961 tacggtaaat cggatactgg aactcgccct ggcgggtatg gcgcgcctga attaccggcg
    22021 tgtaatagcc tgtaaactgc acgttaccat agttgtcggc accttccatc tgccaggcat
    22081 caatgccgaa ctggcgcata ttgcgggtat caccgcctgc gcgcagccac tcttgcaccg
    22141 cgttataaac attactctgg ttgccataca gacgcggtga cgaattacgg atatggttaa
    22201 tttgctcggc aaaatcaccg gcgttaatcg gcgcgccaac ggcatctggc tggttcacca
    22261 gagagaaagg ctgggtaaat ttcccgtctt tatattgctg tccgcgatcg gttggtttgg
    22321 aagagcaggc ggcaagcatt gccacaaccg tgcccataag aaggtacttt acccaacgtc
    22381 ctttcattgt tctcttcttc aggttaaaaa ataaggcgca acgaagataa caaaccgccg
    22441 cgtttaatga aatgagcagc ctctccctga cgcaaatttt gcacaaaaaa taggctttag
    22501 tgatttgttt ttgttcaaaa tcatgccaaa tccgtgatcg gggtaaaaaa aaggttgcat
    22561 gaaaacgcga gcggagtata gtgcgcatcc acggacgcgg ggtggagcag cctggtagct
    22621 cgtcgggctc ataacccgaa ggtcgtcggt tcaaatccgg cccccgcaac caattattga
    22681 acaccctaac gggtgttttt ttgtttctgc tctcccataa aaaaagcgcc attcagcgcc
    22741 tttttatcat ccccttctcg ccagcgtcgc cccatcggca aaatacgctt taattcccgc
    22801 aagaatagac tccgcaactt cctgctggaa agtcgccgtt ttcagtttac gctcttcctc
    22861 aacgttactg ataaacgccg tttcgaccag aatggaggga atatcaggcg ctttcagcac
    22921 ggcaaacccg gcctgttcaa cctgattttt atgcagcttg ttgattttac cgagcttatt
    22981 cagcaccgct ttaccaaact taaggctgtc ggcaatggtc agcgactgca ccatatcgaa
    23041 catggtgtgg tcgacatagc ggtcaccgct tttgctcacg ccaccaatca agtccgaggc
    23101 gttctgggtc tgtgccagat attttgccgc agtactggtt gcgcctttgg ttgagagcgc
    23161 aaacactgag gaaccgctcg gctggcgact ggtaaaggcg tcggcatgga tagagacaaa
    23221 caggtcggca cgctgtttct gggcttttgc tacgcgcact tgcaacggaa tgaagatgtc
    23281 ttcattgcgc gtcatgtaca ccttcatatt gccctctttc tcgatcagag agcgcagacg
    23341 gcgagctatt tgcaatacca cgtctttttc gcgcgttttg tatttcccca ccgcaccgga
    23401 gtcttcgccg ccgtggccag ggtcaagcat aataacaata ggacgatcgc gccctgcttt
    23461 acccggttgt ggaccacttt gtgctggcgg cacctgcttt tcgaggtcgc ctttgttgta
    23521 atcctccagc agcgccagca gcgggtcctg catatcctgt gcattggccg gatagaggtc
    23581 catcaccaga cgctctttaa acccggcgac cggcgcaagg gcaaacagct gcggttttac
    23641 gttttgcttt aattcaaaaa ccatccgtac ggtctgcggg tcaaattgcc cgacgcgcgc
    23701 cgacttgatg aacgggtcgt ctgcacgaat ttgtgccgcc atccccttga gtaccgagtt
    23761 caggtttaca tcttcgatat ccaccaccac gcgttccggg ttactcaacg cgaactgctt
    23821 atatttcagc tgacgatttg attctaccgt cacgcgggtg tagctggacg caggccagac
    23881 gcgcaccgcc acgacctggc taaccgcagc caggctgacc tgacttacgc tcaatagcca
    23941 catagcgccc gcgccttgca gtaaacgacg acggctgatt gcagtgttgg atcctgacat
    24001 gcctctcccg agcaaaagaa atctaagctg tgtaacaagt aaacgactaa tttgaccgga
    24061 aactttagcg aaagacgcat aatctgtcat ctaataaacg gtaaacattc tttttatatt
    24121 cacggcatta ctgataaaaa agtcgctctc gcataaaatt tacacttgca ccctgcgaaa
    24181 aaacagaata aaaatacaat aatttcgaat aataatgcaa aggggtgtgc cgtggtaaag
    24241 gaacgtaaaa ccgagttggt cgagggattc cgccattcgg ttccctatat caatacccac
    24301 cggggaaaaa cgtttgtcat catgctcggc ggtgaagcca ttgagcatga gaatttctcc
    24361 agtatcgtta atgatatcgg gttgttgcac agcctcggca tccgtctggt ggtggtctat
    24421 ggcgcacgtc cgcagatcga cgcaaatctg gctgcgcatc accacgaacc gctgtatcac
    24481 aagaatatac gtgtgaccga cgccaaaaca ctggaactgg tgaagcaggc tgcgggaaca
    24541 ttgcaactgg atattactgc tcgcctgtcg atgagtctca ataacacgcc gctacagggc
    24601 gcgcatatca acgtcgttag tggcaatttt attattgccc agccgctggg cgtcgatgac
    24661 ggcgtggatt actgccatag cgggcgtatc cggcggattg atgaagacgc gatccatcgt
    24721 caactggaca gcggtgcaat agtgctaatg gggccggtcg ctgtttcagt cactggcgag
    24781 agctttaatc tgacctcgga agagattgcc actcaactag ccatcaaact gaaagctgaa
    24841 aagatgattg gtttttgctc ttcccagggc gttactaatg acgacggtga tattgtctca
    24901 gaacttttcc ctaacgaagc gcaagcgcgg gtagaagccc aggaagagaa aggcgattac
    24961 aactccggta cggtgcgctt tttgcgtggc gcagtgaaag cctgccgcag cggcgtgcgt
    25021 cgctgtcatt taatcagtta tcaggaagat ggcgcgctgt tgcaagagtt gttctcacgc
    25081 gacggtatcg gtacgcagat tgtgatggaa agcgccgagc agattcgtcg cgcaacaatc
    25141 aacgatattg gcggtattct ggagttgatt cgcccgctgg agcagcaagg tattctggtg
    25201 cgccgttctc gcgagcagct ggagatggaa atcgacaaat tcaccattat tcagcgcgat
    25261 aacacgacta ttgcctgcgc cgcgctctat ccgttcccgg aagagaagat tggggaaatg
    25321 gcctgtgtgg cagttcaccc ggattaccgc agttcatcac ggggcgaggt tctgctggaa
    25381 cgcattaccg ctcaggcgaa gcagagcggc ttaagcaaat tgtttgtgct gaccacgcgc
    25441 agtattcact ggttccagga acgtggattt accccggtgg atattgattt actgcccgag
    25501 agcaaaaagc agttgtacaa ctaccagcgt aaatccaaag tgttgatggc ggatttaggg
    25561 taagcgatga aaattgtcgg atgcgacatg cgtaacactc gtgcgtcgca tccggcaatt
    25621 acgtttattc ccgcgaacta aacaacgccg ccagaccact gcgccgctca gtacgagtgg
    25681 cgattgccgc acttaatata cgctcatcgg catacagcga cagacggcga cgcgcgcggg
    25741 tcaccgcggt gtataccagc tctcgcgtta ctaccggcgt gcgttggctc ggtaaaatca
    25801 acgccgcatg gtcgaactcc gatccctgcg atttatgtac cgtcatcgcc cacgtagttt
    25861 cgtgctctgg caagcgactc ggttgcacag acttaatatt gccgtccggc atcgcaaacc
    25921 agacgcgcgt cccctgcccg cgatccagcg caataccgat atcgccatta aacaacccaa
    25981 gcgcgctgtc attacgggca atcattaccg gtcgaccttc gtaccaacga gagtgcggat
    26041 gacgatgaat tttgcgcttc tgttgcataa actgctcaat tcgctcattc agtccagcca
    26101 cgccaaacgg cccttcccgc agggcgcaca aaagttggta ctcattgaac gcctgaatga
    26161 ttaaatccgg ctcggcacgc gcttgcagca gatccagata acgtccataa cccgcaagag
    26221 cttcctcaag catcgcaata taatcttctc cgctctgtaa aagccgtttt tcgatatcag
    26281 taaaatcctg ctgaaaaacg gttttcactg ccgttttatc accacggttg atcgccgcag
    26341 ctaactgacc aatgccagaa tcactgccga aacgatagct tttttgcagc aggcagagac
    26401 tgtcgcgcaa agatgccgct tctgtgccag ttcctgccgg aacgtgagtt cccgtcaggc
    26461 ggcttagctg cccggcacgc tcggcggtaa agccggcatt ggcataagcg cagatatcgc
    26521 ccagcacagc cccagcctca accgaggcca gttgatcacg atcgccgaga aagatcactc
    26581 gcgcatgatc gggcaaggcg tcgatcagtc tcgacatcat aggcagatcg atcattgacg
    26641 cttcatctac caccagcaca tcaagatgca gcgggttacc ggcatgatga cgtaaacgct
    26701 ggctacccgg ctgcgcaccc agcaatcggt gcaaagtact ggcatcttcc ggaatgcgtt
    26761 tcttttgttc atcggtcagc ggtaactgtc gcaaagcctt gccgagagat tcggttaagc
    26821 gcgcggcagc tttacccgtt ggtgcagcca gacggatacg gcagcgttcg ccgtcggcca
    26881 tttgaattaa cgctgccagt aacttcgcca cggtggtcgt tttaccggtg cctgggccgc
    26941 cggaaatcac cgagatccgc cgcgtcagcg ccactgccgc tgcaactttt tgccagttaa
    27001 tttcatcgct tactggaaaa agtttgtcca gggtttgcgc cagtagagct tcatcaacct
    27061 caatggcatg attcacctca ttgaagaagc gcgctaccgt ccgctcgtta caccacatgc
    27121 gattcaaata aagacgatcg ccacagagga tcatcggcgt gggttcatct cccctgctga
    27181 ccgcttgaga agccagcaag cattcttccc aattttgtag ctcaccgatt tcactgacac
    27241 aggtcgccaa cagcggatgc gacgcctcgt tattttccag tcgtgaaagc ggcaaacaga
    27301 cgtgtccctc tccggcatca tgacttaaca gtgccgccgc gagggtgacg gcaggatgtt
    27361 catctcccgc cacggtcagg gcaaattgca catccagcgg gcgtagctgt ttgtgctcca
    27421 cagcttccag taattgcttt tgcaatttca ttacgcctcc tccagggtca taccggcaaa
    27481 catctcatcc atcagggcaa tcaacccggc gttgggtcgg gttgtgtaaa tcccttgttg
    27541 cggatgttct ttatcaacgc cacgcaggaa cagatagata acgccgccaa agtgacgatc
    27601 atagtcgtaa tcagcaatgc gatggcgcag ataacgatgc agcgccaggg tataaagctg
    27661 atattgcaga tcatagcggt gtgcctgcat cgctgctgcc atagcctgtt gggtgtaagc
    27721 cgaactgtct tcacccagcc agttggattt atagtcgagc aggtaataac gcccttcgtg
    27781 gcggaatacc aggtcgataa agccttttaa catgccgcgt acctgcatga actccagcgg
    27841 cgggcagcca gcggatagcg ggtcaaactg gcgaattagt gcatcaagct ggctggcgat
    27901 gagcggttcg ctaatcggca ggtaaaactc catctccacc tgtttatcgc ggtcggaaag
    27961 ctgactcagg ctaacacccg tttcattgag aggtgcctgg aggacagccg tgatccactc
    28021 ggtcaacacc ggttcccact gcgattcaaa gccgccgagt tccagttttt cctgtaccca
    28081 gttcgggtca accggctggg taaaatcgag gtcttcaaac aaactgtgca agaatgtccc
    28141 cggtgacgca ccgcgcggga actgatgcgg tgttaacgtc ggttcttcaa cgacgctgac
    28201 cacgcctgcg gcatcaacat ccagccgtgg catcagatcc tgagcgatac cgtgaccacg
    28261 ctgctgcaag ccggagtagc tggtgacacg ccagttatcg ccgggcaatc gttgtagtgt
    28321 cctcgcattc agttctgcag ttaaagcatc attaacctgc cagggctggt tatcaccagt
    28381 ttgtgccgtt tgccaggcaa tatcatcatc gcataacgct tcaatacagg tgcgaagccc
    28441 tgccgcatct tgcggttccc ctttttgcag caaacgcccg agcgcacttt ggtggacgtc
    28501 ggtgtcacct tttttatcgc cacgacggcg caccagcggt gcaacgccga gactgcaatg
    28561 ccaaaccgaa cgcgtcagcg ccacgtaaag caaacgcaga tcttccgcca gacgttcgac
    28621 ctccgcgagg tcgacgcttt ctggcgcagc gttaagatcc aaaactgcct caaacgagtg
    28681 gcgatcgtga taaaacgcct gatcctggac gcggaaattg gtgataaacg gcagccagac
    28741 caatggatat tccagccctt tcgatttgtg gatcgtgaca atctgcacca gatgtttatc
    28801 actttcgaga cgcatttgtt ggctggaggc attactgtct ggctcgagga tatgttgcga
    28861 taaccagcgt accagcgcat gttcactttc cagctgcgtt ccggcttctt gtagcagttc
    28921 gctgatatgc aagatatcgg taagacgccg ctcaccgcct gccgttgcca gcaagttttc
    28981 agcaatgtta cgcgccgaca tcagcgcccg cagcatcggc ataacgccac gtttgcgcca
    29041 gatttgccga taaccatcga actcttcgac taccacatcc cacgcatgtt cgtcattgtt
    29101 cagcgtttcg atatccagcg cgttcagccc catcattgac gttgccagcg cactacgcag
    29161 ggtgttctca cgttcgggcg tcatcaccgc ctgcaacaac caaagcattt cctgcgcttc
    29221 cagagtttca aaaacactgt cgcggttcga aaggtaaacg gaagggattt ccagcaacgt
    29281 taaggcgtcg cgcacctggg cggcctcctg gcggctgcgc accagcacac tgatgtccga
    29341 agcacgcacc ggacgcgcgt cgtcgccgtt catcagcaac gcttcgcccc gctgtccggc
    29401 ttgtagccag tcgcggattt gcgcagcaca tacctgcgcc atggtacttt gatagtcgcc
    29461 aacgccgcag ctttcgcctt ccatcagcca cattttcatc gcaggctgcg tttcaccttt
    29521 aaacacaaaa cgtaacgcct gatttttccc ggctgatttc actggaataa acggtatttc
    29581 gcgaaacatg aacgcgtcat cagtctggct gaaaagcttg ttcacactgt tcaccattcc
    29641 tggtgcggaa cgccagttgg tgtctaaagt gtagtgggcg tgaacttcgc tacgcgcctt
    29701 catataagtg aagatatccg caccccggaa tgcatatatg gcctgtttcg ggtcgccaat
    29761 cagcaacaat gcggtttccg gctgatggtg ccagatacgg cgaaaaattc ggtactgctg
    29821 ggggtcggta tcctgaaatt catcaatcat tgccaccggg aatcgcgtac ggatcgccgc
    29881 tgccaacacc tcgccgcttt cgctacgcag cgcggaatcg agccgactta acatgtcatc
    29941 aaaacccaat tcgccacggc ggcgtttttc acgcgctact gtttcgcgga tctcagccaa
    30001 tgcgcgggtt atcaccagat cacggatcga caatggttct gcaagcagtt gttcgatcgc
    30061 ctcaaacagt ggatgtcgcg gggtttcccc cccggctttc gtgcgatctt ctaagaaacg
    30121 ctgagagaat ttttccagcg actccggtaa ctgataactg ttggtctctt cttctgccca
    30181 ggcgctgatc ttctcgatcc atttagcctg attgctacgg ttaaacttgc gtcgatcaat
    30241 accagaagat tcgatcagcg catccagttc acccactgcg tcgcgccact gctgttttac
    30301 cgtatcaata cgcgccacaa tttgcgcgtg gcgggaagcc agcgtttcat catcgggcgg
    30361 cggtgctttg ataaccggtg cttcgccttg cagataacga ttaatatcgc gcagcaacgc
    30421 ctgcggccct ttccaggttt caaagaccac cagggcaatt tcacgcggca gcgggtagca
    30481 gtggcgacgc cagaaatcgg cgcaggcctg gtagcgtagc agagactcat cttcaatcag
    30541 ctgctgctca aacagcatac cggattcaaa ggcattcagg ttgagcatgc gctggcaaaa
    30601 accgtgaata gtaaagactg ccgcttcatc catctgccgt tcggctaaca acaaccactg
    30661 cgcggcttgc gctttatcgt cgatctcttc cagcaggcgt tcgtacagtg gattgtcggt
    30721 ggtttcacgc agacaggcga tgcgcaactc gtggatattg ctacggatac gaccgcgcaa
    30781 ttctgccgtg gcagcctcgg taaaggtgac caccagcagt tcttcaacgg tcagcgggcg
    30841 gggaaaggcg gcggaaccgc ctagtccaag taacaggcgc aaatagagcg ccgcaatcgt
    30901 aaaggttttg cctgtgccgg cagaggcttc aatcaggcgc tcgccctgta agggcaagcg
    30961 caaaggatct agtgtctcgg cgacatcact cattcttttc actcatcagg ggcattgttt
    31021 gctgcaacgc gctgacgttc tcccacactt tccagccttc aggatgcaca tattcggctt
    31081 tcccgttctg gctgccggaa atctgcgaca ggatagccat gccttgcggc tcgaccaccg
    31141 cctgatggaa gaaatcagca agtttttgcg gcgtcagcag ttttatctgg gccacgattt
    31201 tatcacgcga atcgaagcgc atattgccgc gatcgaaatc tttacttaac ttcgatgctt
    31261 cttcgccgag cgtttgcggt gcctgcagca tctgggtaat taccgcctgc tggatttgcg
    31321 caaactcatc tggcttcatc gctcgcaatt ttgcctctgc ggttgggaaa aacgccttgt
    31381 aacgctccca caagaatgaa ggctgtttat cattgctttg caaaaggaag cccatgcccc
    31441 actgacgccc cacgctcatt ggaaacgcaa acacggcata gcccaattgt tcttcggtac
    31501 gcaactgatt gtagaaccac ggctgtacga tctgccccaa cagagagcta taggctgagc
    31561 tggtgtattc atcgtagcca gtcggtacaa ataccgctgc cagtgcggag tcggtgctgt
    31621 taccggcttt ttcaaagatg acggattgtt ttttatcgac cactacatct ttgtttcgac
    31681 accactctga accatcagcg cccaactgtt tttgcacatc gcgtgccagc gttgttgcct
    31741 gggcctcggt catgttgccg ataaccataa actctggtcg agcccctgat tttaaggcgt
    31801 cgcgataggc cagcacctct ttcaacgtaa tggagggcaa aattttacgc cgttcatctc
    31861 gcgagaagta cggcacttgc gagagcatct gcgcgggcat aatcgcctgc tcaaacgctt
    31921 tacccttttc tgcggaatcc atcatctggt tataccagga cttcgcctgc tcaagctgat
    31981 cttccgtagc ggtatagcta aagtacccct cgagcaatgc ctggaacagc tgcggcagac
    32041 gctgggtgta accattagca ttaaccataa ggccgttgtt agcgttggtg gaaaaactta
    32101 tgccaccaac cgacgcctgg ttgcttaact gatcaagcgc cagccctgcg agataatcat
    32161 tgagcgcaaa catcacctga ttgcgggcgc tgtccatggc tttcggatta cgcaaaatca
    32221 ggctgacatc agctttgggt tcgctggaaa aataacggct tggcgcatac accacgcgca
    32281 gattcgactc atcaacaatc agctctggat ggtcatattt cttctctgac ttaatcagcg
    32341 agaaatcgtc aggaatatag gggttaagct ccggtaagga gagcgcaata ttggcagctt
    32401 tttgctgcca gtcagcgaaa gtttgttcgc tgattttatc gacctgatac ggcgcatcga
    32461 caaaataagc cgttttattg tgcggctctt tcgggctgat ataccagata cgcgcattct
    32521 gcggcgtcat catcgccaga cgttctttta ctgctttagc atcgtaccga tcggcaatat
    32581 tgactgcatc cagcgtatgc tcaaccggaa cgcgaatcat ggtatctgcc agccattcga
    32641 cgtaatccat atcacgggtg atcgacggat aacggaagtc gatatccagc acattcgcca
    32701 gttcatcgaa gtattgttta tcaatgcctt tttcacgtaa cagattgaga tagctaaaaa
    32761 ttgccgccac aacctgatcg cgattagcca ggcctttatc ggttaaagac gcagagatcg
    32821 ctaatacgcc gctgttgccg ttgacgatag gatcggagtt ggcgctaatg ccctcaacta
    32881 atccctgctt ttgcagccag tcggaaagtg tacctgggct gcgattacca atcagatagg
    32941 taatcaattc atccgtttta ctacggaact tcgctgagtt gttatcgatg cgaaactcaa
    33001 cgcgcagaac tttacgcggc agtgccggga cgtaatgaat gataatgccc ttttgcgcgt
    33061 cggtgactac cggcacggtg atttccggtt ttttgctctc tttgttcggc acgcgaccaa
    33121 aggtgtccgc cgccattttt gccaactccg gcagcggttt attgctgtaa ataaccgcct
    33181 tcatcagatt ggcggaatag tacttctcgt ggaaatcttt cagcgcctgc tgcaccggat
    33241 taccaggttt atcgcttaaa gtttcgaggt taccaccaga aaactttgaa ccggggtgtg
    33301 ccgggttaat ggtttctgcg ctgacctgtg ccatgcgcat cccgtcacgc gtacgcgcca
    33361 tggttaattc agcgttcacc gcattacgct cacgttcggc atatttcttg tcgagcaaag
    33421 gttcagcaat agcatcggcc aggcggtcta ccgcaccagg caaggcgtcg ttctcaactt
    33481 ccagatagaa agccgtgcga tacggcgcag tgctggcatt gtgactaccg ccgtgcattt
    33541 tgagatattc ggccagactg tcagcctgcg ggtacttttt cgaccccatc agactcatat
    33601 gttcaaggta atgtgccagc ccctggtacg cctcgggatc ttccagcgac ccaacgggca
    33661 ccaccagcgc cgagagcgat ttaactgcct gcggatcaga aaccagcaag accaccatac
    33721 cgttatccag acgtatagcc tgatactggc ggttatcttt atcactttta cggatggttt
    33781 cctgaatcgg ctgccatccc gtttctgcct gacttaaggg tgcccaaagg gcaacaaaca
    33841 acaataatgc tttgaaccag gtgctgcggg gcattcacgg acctcataat caactttatt
    33901 ttctggccag attcaacagg ttaacgcaaa tcatctgcca gaatttaatc ttgtgctgca
    33961 cgagtcagcc tatgtctata tatccatcag tccgtgactg gtgcgcatca taaagtaagc
    34021 ggatagattg cgcaattttt atacagcact catgactgat taaagcgaaa cagcggtaac
    34081 aggaaacgtt gcgactgttc aacgatggcc tccattgtct ctggtgttaa ttgccgccag
    34141 agcctttgat accagatatc atcaccttcg ccacgcacca tcatgttgcc ttcgtaagcc
    34201 tgaaggaatt tcgtacgggc tttttgcaac gtggaatcgt catccagcat ggcatcgttt
    34261 tgcgcgtcat aacaggtttt tagccacgcg ccgccacttt caggtaacac cagcaatggc
    34321 gcggacatcc cttcacgata cccctcaatc agttgtgaga ggtaatgcaa agcctgttcg
    34381 gctgcaagcg gcggaaaacg ccactcgccg tctttgcgta gaaaaaggcg actttcacca
    34441 ttaccaccgc tggcacagta gacaaggtgt tccagccaaa gttgcattcc ctgcgccaca
    34501 cttaataaag agggacgcca gcgcaacagg ccatccggct gcacctgcgg caaccagcca
    34561 gttatctgca caccgttgca ggcgagatca atttccatac tctgccccgg ctggcgacag
    34621 gcaatgactc tgtcggcaag ctgctgcatc tcctggcact gtgtttccca gaaaatttca
    34681 ccaaaagcgc catacggtaa atcccctgcc gcccggaagc ggcggaacaa gcgttcggca
    34741 tcatcctgct caaccagtgc attcaataac tgctgattga tttgataacg gctaagccct
    34801 tccagaataa atggctcggt gtctgggatt tcgctgtctt cagtacggaa gttcacctgc
    34861 aaacgcatct ggaagaacgc ccgcaccgga tgtgcccaga atcgttgtag cgtttccagc
    34921 ggcacggttt ccggtaaggt aaacggcagc ggctgaacaa attcagaatg tgctttacca
    34981 gcctggctgg ccgcaggtag ccattcacga gcatagcttt gtcgttcgcc tggctggtag
    35041 ttttgcggat caaacggcat ccgggtatgg aggcaagtaa gatgcgcttt tacccttacc
    35101 tcgctttcat cacagttgag cgcttcatcg cccggtagat aatgactttg cccgatgtag
    35161 tcgatcagtt cctgcaccag taccgacggg aaacgttcac tgttatcctg aatggaacgc
    35221 ccgatatagc tgatatagag tttttgctgc gcggaaatta acgcttccag gaacaggtag
    35281 cggtcgtcat cgcgacggct acggtcgcca cgcttcggtt tctggctcat caggtcaaag
    35341 cccaatggcg caagctgacg tggataaacg ccgtcgttca ttcccagcag gcaaaccact
    35401 ttgaacggaa ttgaacgcat tggcatcaga gtacaaatgt taaccggtcc ggcgagaaaa
    35461 cgctggctga tacgttcttg atccagacgc tgcgccagtt catcacgcaa tagtgacagc
    35521 ggcaccgcgt cgccatactg cgcacctaaa ccttcggcga taatcgcctg ccattgttgt
    35581 tcgatcagcg tcatcgccgc ttcggtttcc gcatccggca ggaagaaggc gttgagcata
    35641 tcgcgacaaa ccggcaacca ctcttctagc ggacgctcct gtgccagccc gcgacgccag
    35701 atgtttagct gcattagcag tgaagccaga tgccccacca gttctgcaat taagccgctc
    35761 gattcatcat aaggtagaac cgattgccac tcgccctgcg cgctctccat cgcgtagccc
    35821 agcaacatac gcgtcaggcc aaatcgccag gtgtgttgtc cggtggtggg gagttccagc
    35881 tcgcgaacgt tgtcgtcatc tatcccccaa cgaatgccgg attcgttgac ccactggcgt
    35941 aaataacgca gcccttcttc ggtgatgtca aaccgcgccg ccagcaccgg cacatccagt
    36001 aatgccagca cgtcttccga cacaaagcgg ctgtctggca acgataacag gctgataaac
    36061 gcttccagta ccggatgcga ctgccgcgcc cgacggtcgg aaatggcgta aggcaggtaa
    36121 cgatccgcag gtgcgctacc aaacacagcc tgaataaacg gactgtagct gtcgatatca
    36181 gccaccatca cgatgatgtc gcgcggagta agtgtcgggt cttcttccag catcgccagc
    36241 aggcgatcgt gcaaaacttc aacttcacgc tgcgggctat ggcaaacgtg gaaggtgata
    36301 ctgctatcca gtggatcaag cgggcgtttg ttatcgctac gggaaaactc ttcgatgttc
    36361 acaccagcaa cggcacggtt ttccagttcc agaatgtcag actgaatgtt atgcagcagg
    36421 ttatctggcg tgacatcgac aaaggcgtcc agctcctggc tgctctccag gtcagaaagg
    36481 agataaatgt agtcgcgccc aagcttaccc catgaagcca gcagcgggtt gccgacatcc
    36541 tgttcaccat cgctgttaaa gagctgcccg gcattttcgc tatcacgaaa tagcggcaat
    36601 tcgcgatctt caaaactgtg tcgacgctga cgggtcagca gtttcgccag ataagcagga
    36661 tctttaatat cgccccagta ataacggcag gggttggtaa acaggagatg gatttcaata
    36721 tgtttaccca gcgcctggag cgcctggaga taaacaggcg gtaacgcgga aataccgcat
    36781 ataaagacgc gcgaaggtaa ccccggcggg caggtcgtcg cggactccag cgtttcgata
    36841 aagcgctgat agagattggc gcggtgccaa cgcggttgtc cgagttcatg ggtatattcc
    36901 accagcgcct tccacaacgg cgcttgccag gcctgtgctt ctcccagccc ttcaaccaaa
    36961 tgtcctgttt cccactgtgc cagccactcc gggcgataga ccagatactg gtcaaacagg
    37021 tccgccgctt ttgaggaaag ctggaacagt tttcgcttgt cgctatcgtc agtcagataa
    37081 tgccgcaaca gggtaaagtc ttcgcgatcc agcaattgcg gcagcagagt catcagtttc
    37141 cagctcatgc tctgtttgtt aaaggcgctc tctttgggga tctccggtaa cacccggacg
    37201 aacatatccc agataaagct cgctggcagc ggaaaatcaa tgtttgccgc aataccaaac
    37261 ttttgcgaca gggtcatttg cagccactgc gccataccgg tactttgcac cagaatcatc
    37321 tctggttcga aaggatcgtc cagccgttcg cgttcgacaa taaactccat caacgcttcc
    37381 agcacgtcca gacgattgga atggtagacc cttaacatag cggctcctga ctactgacga
    37441 ttcgggcaat gcaggcgggt catctcgcct tctctgcccc cgggtgaaac tagcgtaacg
    37501 ctgatgctga cacatcccgc ctgcgatgtc tgcattcggt tgacctgcca gttggcaggt
    37561 ggcgaaatcg cgcgcagttg cgtttgctgc caaccatgcc gccagagctg ttggtactgg
    37621 tttctgctgg cgagactgtt cattaatgtt cgctggatac ccgataacgc agtgacaatc
    37681 atcaccatca gcaccatcgc aaccattacc tccggcaggc taaagccttg ttgattcttc
    37741 agggaagctg acataacgcc ctctctttca gcggacaaaa atcgctccag ccgcgtggcg
    37801 aaaaaacaat gtttccatca atgacttcgc ctgttcgcca caacgaaacg ccttcataac
    37861 cggcaaccaa taaggcttca ttatctgcca gtaaacgcaa acaaacccgg gcatcggttc
    37921 cagcgtactg cgagcactga actgcgggct gcgtctgcca ggagtgcatt ttcccccacg
    37981 ccagcgccga ctgaacgatg gcctggcggc gcaatgactg actttccatg ctcacgcgag
    38041 aggcaaaact gcgatcctgc tgactcattc cttgcaatag caagctaccc aaaaccagca
    38101 gcatcagaac cagagccagt gacgaaacac ctttttcgcg gttcacaggt tgaatcctgt
    38161 cacgctatag ctggcatcca ccacggtttg cggttcagac ttactggcag cacgcatatt
    38221 aaccgtcaac accggcgaga agccgctgac atcctgacgt acgacctgaa aagtgtcgat
    38281 aatgatggca tccggattag tgactttatc ccagccctta ccttcacagg atgtcgcacc
    38341 gcgtagcgtt tccagcacat gctccttcag acgaaatcca atctggtcag actcttttac
    38401 cggttcgcga tcccagatac cgttactgtt cgcatcccac tgcacaatga tacagtcacc
    38461 ctgtccgaca atttccagcc cttcgccggt acagctgcca tgacaataac ccgccctctg
    38521 gagatgcttc gcgacggtaa atacccgcag ccagatttca tcttccagcg ccagcttacg
    38581 ggtgctcgtt aaactttcac gctgtaacgc aggcagaaag cgtgcagccc ccagcaacaa
    38641 tacgctactg atcgccatag caatcaacac ttccagcaga gaaaaacctt gctcttttac
    38701 aggcatcctt ctgtttctcc ttgctgacaa agccggagtc ttccccacgg cgaaaccacc
    38761 agccaccact cgcccgttga gtttttgaag cgaatatgcc cggcccatgc ggtattgcgc
    38821 aggccaaaga aagcaagcga aggtgtcagg tcgctcattt cgacttcggg ccagcgtggc
    38881 acaaagacca atggtgaact gccatgacag gtattggccc cagcagcgga actcacaagg
    38941 caccataacg tcccctccct gataacgctg atactgtggt cgcggttatg ccagttggca
    39001 tcttcacgta aatagagcaa atagtcccgc gcctggctgg cggtttgcca tagccgttgc
    39061 gactgctgcc agtattgcca gccatagagt ccacttgcgc ttagcatgac caaaatcagc
    39121 atcgcgacca gcgtttcaat cagcgtataa ccacgttgtg ttttcatgcc ggcagtatgg
    39181 agcgaggaga aaaaaagacg agggccagtt tctatttctt cggcgcatct tccggactat
    39241 ttacgccgtt gcaggacgtt gtaaaatttc gggaaggcgt ctcgaagaat ttaacggagg
    39301 gtaaaaaaaa ccgacgcaca ctggcgtcgg ctctggcagg atgtttcgta attagatagc
    39361 caccggcgct ttaatgcccg gatgtggatc gtagccttca atctcaaagt cttcgaaacg
    39421 gtagtcgaag atggattcgg gtttacgttt gataatcaac ttcggcagcg gacgcggttc
    39481 gcggcttaat tgcagatgag tttgatccat atgattgctg tacaggtgcg tgtcgccccc
    39541 cgtccagaca aaatcgccca cttccagatc acactgctgc gccatcatat gcaccagtaa
    39601 cgcgtagctg gcaatgttaa acggcaggcc gaggaaaacg tcacaggagc gctgataaag
    39661 ctggcaagag agtttgccgt ctgccacata gaactggaag aacgcatggc acggtgccag
    39721 cgccatttta tccagttcgc ctacgttcca cgctgaaaca ataatgcggc gcgaatccgg
    39781 gtcgtttttc agctggttca gtaccgtagt gatctggtca atatgacgac catctggcgt
    39841 tggccaggcg cgccactgtt taccatacac tggtccgagg tcgccgtttt catcggccca
    39901 ttcgtcccag atggtgacat tgttttcgtg tagataagca atgttagtgt cgccctgcag
    39961 aaaccacagc agttcgtgga tgatggaacg caggtggcaa cgtttagttg tcaccagcgg
    40021 gaatccatcc tgcaggttaa aacgcatctg atgaccaaaa atggaaagcg ttccggttcc
    40081 ggtacggtcg tttttctgtg tgccttcgtc gagcactttt tgcatcagtt ctaaatactg
    40141 tttcatggtt cctcaggaaa cgtgttgctg tgggctgcga cgatatgccc agaccatcat
    40201 gatcacaccc gcgacaatca tcgggatgga aagaatttgc cccatgctga tgtactgcac
    40261 ccaggcaccg gtaaactgcg cgtcgggctg gcggaaaaac tcaacaatga tgcgaaacgc
    40321 gccgtagcca atcaggaaca agccagagac agctcccatt gggcgcggtt tacgaatata
    40381 caggttgagg ataataaaca gcaccacacc ttccagcagc agctcgtaaa gctgtgatgg
    40441 gtggcgcggc agcacaccgt aagtgtcgaa aatggattgc cactgcgggt tggtttgcag
    40501 cagcaaaata tcttctgtac gggagcctgg gaacagcatg gcaaacggga agttcgggtc
    40561 aacgcggccc cacaattcac cgttaataaa gttgcccaga cgcccggcac caagaccaaa
    40621 cggaatgagt ggtgcgataa aatcagaaac ctggaagaag gaacgtttag tacggcgggc
    40681 aaagataatc atcaccacga taacgccaat caggccgccg tggaaagaca tgccgccgtc
    40741 ccagacacgg aacagataca gcggatcggc cataaactgc gggaaattgt agaacagaac
    40801 ataaccaata cgtcccccga ggaagacgcc gaggaagccc gcatagagta agttttcaac
    40861 ttcatttttg gtccagccgc tgcccggacg attcgcccgt cgtgttgcca gccacattgc
    40921 aaaaatgaaa cccaccagat acatcaggcc gtaccagtga agcgccacgg gtcctattga
    40981 gaaaatgacc ggatcaaact ccggaaaatg cagatagcta ctggtcatct gtcaccacaa
    41041 gttcttgtta tttcgctgaa agagaacagc gattgaaatg cgcgccgcag gtttcaggcg
    41101 ctccaaaggt gcgaataata gcacaagggg acctggctgg ttgccggata ccgttaaaag
    41161 atatgtatat gatccgcgct ataaccctcc gcgaatcagc ccgcccatgc cgcgacgctc
    41221 cataaaggct gcaacctgat ggcgaacttc ggtcgccagt tgcgcttcca gactacgctg
    41281 cgcaagattt tctgcttcgg cataatcaat gcgccgcagc aggtatttta cccgcgctac
    41341 agaacgtccg ttcatagaca gatggcgata cccaagccca atgaggattg ccacgcacat
    41401 gggatcgccc gccatttcac cgcacaaacg gagatcgatt ccatgtattt ccgcttcccg
    41461 ggcgatcatc gccagagctc gtaacattgc aggatgaaga ctgtcataaa tgttcgccac
    41521 ccgggtattg ttgcgatcaa cggccagaat gtattgagtc agatcgttgg tgccaacaga
    41581 gatgaaatcg acccgctttg ccagatgcgg cagcataaat accattgacg gcacttccag
    41641 catgatgccg atacgtggtt tgggaatttc gtaaccgatc atctcctcga cttcacgtcc
    41701 ggcacgttca atcaggcggc gtgcttcatc aacttcatcg aggcttgtga ccatcggcaa
    41761 cagaatattc aggttgcccg tagcggcatt agcacgcagc atcgcccgca cctggatcaa
    41821 gaagatctcc ggctgatcga gcgtaatgcg aatcccacgc caacccaggc atggattctc
    41881 ttcgctgatc ggcatgtaag gcagctgctt atctgctccg acatccagcg tacgcaaggt
    41941 gacgggttta tcattgaaca tttgcagcat cccctgatac tgcgccacct gttcttcttc
    42001 cgacgggaaa ccactttgca gcatgaatgg gatttcagtg cgataaagac cgatgccatc
    42061 aatacggctg cccagttttt cttcatgttc cgggcttaaa ccagcattga gcatgacttt
    42121 tatacgctca ccgcttttta actgcgcggg taaattgacg tcatcttccg ccagacggct
    42181 aagctcaatc tcttcactaa ttagccgctg atattcttgc agcagtaccg gctccggatc
    42241 gaccagcaat tcaccgcgat agccatcaac gatcagcgtc ctacgatgca gcaccgaagg
    42301 ctgaatatcc gcgcccatca cggtagggat ccccagcgca cgtaccatga tcgcagcatg
    42361 ggagttggct gcgccatctc gcacgacaac accgactaag cgatcctggg gcagctcagc
    42421 aagagttgtc gctgacagtt catctgccac cagaatgaaa cgttccggcc aggcgttcgg
    42481 cccttgatta gcgtcatcaa gatgaaacag caatcgctga cccagcgcac gtaaatcgcc
    42541 agcccgctct ttgagatagt tatcgcttag cgcggcaaac tgttcggcaa atttttcaat
    42601 gaccgttttt accgcccact ctgccaccga gcctttatca acctcggcaa acaattcgcg
    42661 acgcagccgg gtgtccgaaa gcaggtgcga gtaaagatcg aaaatagccg ccgtttcttt
    42721 ttgtgcaccg gcggcaaagc gtttgctgta gcggcgaaac tcgtttgccg cttcttccag
    42781 cgccccggtc agtcgttcgc gttccagagc cggatccagc gttgatgcct gatacacctg
    42841 ttccattaaa ggtaacgtgg catcctgcca gccttcggca atcgccacac caggtgctgc
    42901 cggtaatgcg cggattcgcg tctggcgata ttgcccaaac agggcagtca actgcgactg
    42961 agaaagaata gctgccatct gggtggcaag cgtcaccagg aaggattctt cactttcgtc
    43021 atactggcgc aactctcgtt gctgtaccac cagtacacca agcaactggc gacgttgaat
    43081 aattggtacg cctaaaaacg cgcggaaacg ttcttctttt acggagggga tgtatttgaa
    43141 gctggggtgc ttttgcgcat ctgcaaggtt tatcggttcc gccagcctgc caaccaggcc
    43201 gacgatccct tcatcaaacg cgagcgttac agtgcgaccg cgtggttttt tcagcccccg
    43261 ggtcgccatc aggtagtaac aacgtcgatc atgatcggcc aggtagaccg aacagacctc
    43321 ggtatccatc gcaagacaga tgtcggtaac cagaatattt aacgcctcat tcaggcgtgg
    43381 tgcgctggct accttttcga ctatttcgcg caggcgagtg agcataattg gcgtgactta
    43441 acctctttta cgtcgataag cagatgcgtt ttgtggtttt ggcgtatttt cctgcagtga
    43501 catcaccaca ctcgcgaact ctttcattac cctacggtag acatcacgtt taaatgacac
    43561 cacctgtctg accggatacc agtaacttac ccatcgccag ccgtcaaact ctggtgtact
    43621 gctggtttgc atattgattt ctgcatcgcc gctcaccagc tgcaagagaa accatttttg
    43681 tttttggccg atacaaaccg gcttcgtgtc ccaacgcacc aaacgtttcg gtaatttgta
    43741 gcgcaaccag ttacgcgttg aagcaaggat tcgaacgtct ttgcggctta atcctacttc
    43801 ttcaaacaat tcacggtaca tcgcctgctc tgcggattct ccggggttga ttccgccttg
    43861 cggaaattgc caggagtgct gaccaaatcg ccgggcccac attacctgcc cctggcgatt
    43921 acaaatcacg atacctacgt ttgggcggta gccatcgtca tcaatcaccg gactacctca
    43981 aaataaagct ttatatacga atgattgttt catactccag gaagacggta aaccactctc
    44041 tgcagggcat tacacactaa taacaattga ataactcaca gttatgtgca gagttataaa
    44101 cagaggaagg ggtggatagc cgtttttatt caccttttct gtggatagag ttgtgaagaa
    44161 ctacggaatt actacgggaa aacccggagc attctgaata agcccgatat agacatttta
    44221 aaatattcat tattagtcaa tgcattacat gtaatttgag taatgaaaaa gagtaattcg
    44281 tgacccaggt cacacctctc atttacgggt tggcgaaaga tcaaccaatg ccgtatttat
    44341 ccacagaatg tgccactaag ttaagcactg aaccactaaa aactggagtt tcatcgcacg
    44401 tcaaggctgt aaatggaaac agtagtggag gtttttcaca gttatcccag ctttctgtgg
    44461 ataacatggt gtaagatcct gtttattttc agtgaccaga tttggaaaac ctattgcagt
    44521 gttgcgcaac tcgattaccg gcagcctaaa aagcaatata aatcagggaa ttgaacaaca
    44581 catgtggaaa aagttacact gcgaatattc ggcacataat tgctgtttgt tttttaatca
    44641 aggtatcatg acatgtccca acctcgccca ctgctctctc ctcccgaaac tgaagaacag
    44701 ttgttagcgc aagcacagca actttctggt tatacattgg gagaactggc ggcacttgcc
    44761 gggcttgtta cgccagagaa tttaaaacgc gataagggct ggattggcgt gttactggag
    44821 atctggctag gtgccagcgc agggagtaaa cctgagcaag attttgccgc tctgggcgtg
    44881 gaacttaaaa ctatccctgt ggatagtctt ggtcgtccgc tggaaacaac attcgtttgt
    44941 gttgccccgt taacgggtaa tagcggggtg acctgggaaa ccagccatgt gcgccacaag
    45001 ctcaaacgcg tactgtggat accggttgaa ggcgagcgca gcatcccgct ggcgcagcgt
    45061 cgcgtaggat caccgttgct gtggagcccg aatgaagagg aagaccgaca gctacgcgaa
    45121 gactgggaag aattaatgga tatgattgtt ctcggtcagg ttgagcggat caccgctcgt
    45181 cacggggaat atttacagat aagaccgaaa gcagcgaatg cgaaagcgct taccgaagcc
    45241 attggtgccc ggggcgaacg gattctgacg ctgccacgcg gcttttattt gaagaagaat
    45301 ttcaccagtg cactactggc ccgtcatttt ctgatccagt agccatcgct ttgacctgcc
    45361 gctttccggg catataatta ccgcttcatt tttttggcag ggctttttag atgttatttg
    45421 catggataac cgatcctaac gcctggcttg cgctcggtac gctgacgctg ctggagatcg
    45481 ttcttgggat cgacaatatt attttccttt ctctggtggt ggcaaagctt cccacagcac
    45541 aacgtgctca tgcgcgccgt ctggggttgg cgggagccat ggttatgcgt ctggcgctgc
    45601 tggcatcaat cgcctgggtt acgcgcctga caaatccgct ttttacaata ttcagtcagg
    45661 aaatttctgc ccgtgatttg attctgcttc tgggtggctt gttccttatc tggaaagcca
    45721 gcaaggaaat ccacgaatcc attgaaggtg aagaagaagg gctgaaaaca cgcgtttcat
    45781 cattcctcgg cgctatcgtg cagattatgc tgctggatat tatctttagc ctcgactcgg
    45841 tgattacggc tgtgggtctg tcagatcacc tgtttattat gatggcagcc gtggtgattg
    45901 ccgtaggcgt gatgatgttc gccgcgcgct cgattggtga ttttgtcgaa cgccatcctt
    45961 cggtaaaaat gctggcgctc tctttcctga ttctggtggg ctttaccctg attctggaaa
    46021 gtttcgacat ccacgtaccg aaaggttaca tctacttcgc gatgttcttc tctattgcgg
    46081 ttgaaagcct caacttgatt cgcaacaaaa agaatccgct ctgatactcc gtacgctctc
    46141 ctgcgggagg gcgtactcac tccttttacc ctcacagttt aagattttcc tgctttcaag
    46201 atatataacg tcggtttata aacagactat tatcataggt aggccaaatg aggataaccg
    46261 gatgaaaaaa tgggcagtaa taatttctgc agtcggactg gcgtttgctg tttccgggtg
    46321 ttccagtgat tacgtcatgg cgaccaaaga tggccgtatg attttgaccg atggaaaacc
    46381 tgaaattgat gatgataccg ggctggtgag ttatcacgat cagcaaggta acgcgatgca
    46441 aattaaccgt gatgatgttt cgcaaattat tgaacgttaa caaataaggt cagcatccgg
    46501 ctggccttaa gatttttctc tttccctttt cccttccctc tgccattttt atattcctta
    46561 tgtcgtgatt ataaaaagga aacggctatg caatatcacc gtatacccca cagttcgctg
    46621 gaagtcagca cgctggggct tggcacgatg acgtttggtg aacagaacag cgaagccgac
    46681 gcccacgcac aactcgacta tgccgtcgct cagggcatta accttatcga cgttgccgaa
    46741 atgtacccag tacctccgcg ccccgaaacg caagggttaa ccgaaaccta cgtcggcaac
    46801 tggctggcga aacatggcag ccgcgaaaag ttaattatcg cctccaaagt gagcggaccg
    46861 tcgcgcaata atgacaaggg catccgcccg gatcaggcgc tggatcggaa gaatatccgc
    46921 gaagcgctgc atgacagcct caagcgccta cagactgatt acctcgatct ttatcaggtg
    46981 cactggccgc agcgcccgac caactgcttc ggcaaactcg gttatagctg gacggattct
    47041 gcgcctgcgg tttcgctgct ggatacgctg gacgcactgg cagagtacca acgcgcggga
    47101 aaaattcgtt atatcggcgt gtcgaacgaa actgcatttg gcgtaatgcg ctacctgcat
    47161 ctagcggaca aacacgatct gccgcgtatt gtcaccattc agaaccctta cagtctgtta
    47221 aaccgcagtt ttgaagtagg tctggcagaa gtcagccagt atgaaggggt cgaactgctg
    47281 gcctattcgt gcctgggttt cggcacgctg accgggaaat atctcaatgg tgcaaaaccc
    47341 gctggcgcac gtaatacgct ctttagtcgg ttcacccgct atagcggtga gcaaacgcaa
    47401 aaagccgtcg cggcgtatgt tgatatcgcc agacgtcatg gcctggaccc tgctcagatg
    47461 gcgctcgcgt ttgtacgccg tcaaccgttt gttgccagca ctctgctggg cgcaaccacg
    47521 atggatcagc tgaaaactaa catcgaaagt ttgcatctgg agttaagcga agacgtatta
    47581 gctgaaattg aagcggtgca tcaggtttat acttatccgg caccataaga ttaacgccgg
    47641 ttaaaaccgg cgttaaatat taatgacggc gctgccagat ccacagcgcc gttattgcca
    47701 gcgcaaacag cgcaccgaag ccaatgccaa tgggcacgac cgggatgcct atcattaccg
    47761 ccagcgagta aatgcccagc atcaacaaca tggcgctgtt ttcgccaagg ttttgtactg
    47821 caatcgcatt ccccgccccg acgctttttt taccccgctc ctgtagcaac gcattgagcg
    47881 gaacgacaaa aaagcccccc atcacgccaa tcagcatcaa caaggcatag gctggcagca
    47941 gctcgtgttg cagggaaaaa atcagtacca ccacgccaat caaaatcccg gctggcatac
    48001 agcgtgacac ggtttccagc gtaactaact tcgctgccgc acctgcgcca accacgatac
    48061 caatcgctac catcgcgttg agataggtgg gcgtagcgtt atcggtaatg cccagcgcca
    48121 ccggtaccca cagcaccaac aggaaacgca gcgtgacacc cgctccccag aataaactgg
    48181 tgcccaccag cgaaaaacgc gtttcaccat tgcgccatag cgaggtgcag gcattcagga
    48241 aactgcgggt catgttgatg agattccagg actgccccgg acgcgccgcc gccagtttgg
    48301 gaatgtagat attggcaacg accgcaccac cgtaggccag tgcgcatgcg gccagggcga
    48361 cgaggacatg ccagtcagcc agcacaccac cggctacgga accgagcaaa atcgccgcta
    48421 tggtagaagc ttccattaaa ccgttagctt tcactaactt actacccgtg gttaattcgc
    48481 cgagaatacc gtatttcgcc ggtgaatagg ctgcagcacc aacacccacc agcgtatagc
    48541 cgagaaacgg attgatacca aagcagatac tggctgcgcc cagcagcttc aggccgttgg
    48601 caaacatcat cacccggcct ttggcgaagc tatccgccac ctgcccgaca aacggcgcaa
    48661 aaagaatgta agcacctaca aacaccattt gcaggatggg ctggctccac tccggataga
    48721 actgcgcttt cagtaacgcc agagtggcaa acagtagggc attatcgcca aacgcagaga
    48781 gaaactgcgc cacgataacc gctttcatcc ccttcgacca caacgaagtg ttagtgtgca
    48841 ctgactcact catcgtgttg ttccgcttcg tctacccagc ttttcaacgt gacaaagtca
    48901 ggtttgccgc tgccaagtaa tggcatctgt ttcagatagc gaatatcgcg cggtacagca
    48961 agctccggca cgccgtgctc gcgggcatac tgttgcaact tatcgcgcgt cagttcgtta
    49021 tctgtggtga aaagcaccag tgcctcgcct ttgctggcat cgctcttaat cgcagtggca
    49081 tggactttat ctggcgaaac accaagtgcc agttgttcca ccatttccag cgacaccatt
    49141 tcgcctgcaa ttttggcaaa gcgttttgcg cggccctgaa tctgcacaaa gccctgctcg
    49201 tcaaaacgca caatatcgcc agtgtcatac cagccgcgct ccatttcgcc gcgaacattc
    49261 tcggcggtgg gcacttccag tacacctggc ttctccaccc gcagatagcc gttcattatg
    49321 ttcggccctt tcagttgcag gcgtccgccc tcttcgatac cagggaccga caacaggcgc
    49381 gcatccattc ctggtagaat acgccctacc gtaccgggtt tcgccgccat cggtacgttg
    49441 atagaaacga caggcgcgca ctcggttaca ccatagcctt caaggatgcg caggccaaat
    49501 ttatcctgcc aaagctgttt ggtactttct tgtagttttt ctgcgcctgc caccacatag
    49561 cgtagacgat agaagtcata cgggttggcg aaacgcgcgt agtgaccgag gaaagtcgag
    49621 gtaccgaaca acacggtgca actgcggtca tacaccaact ccggcacaat gcggtaatgc
    49681 agcgggcttg gataaaggaa cacttctgca cctgtaagca gtggcgtaaa caggcctacc
    49741 gtcagcccaa aggagtgaaa cagcggtaat gccgacataa agcgatcgtt ggtggtgaag
    49801 tcggcaatcg ttttaatctg ctcgacgttc gccagaatgc ttttatggct atggacgacg
    49861 ccttttggat ggccttcaga accggaggta aagaggatca gcgcctcttc ttccggctgc
    49921 tgttttacct gcgccaggcg cggcatcagc aaatgagcga agatccatac tttgtcggca
    49981 gtggtgacat ctgcttttaa atcttccaga tagacccagc gcacctgagt aagttgctcc
    50041 ggcagatgcc agagtttgcc tttatcgaga aactggcggg aagtgaagat ggttttgatt
    50101 tcagccgccg taatagcact ggtcagccct tttaccccag cagtgtagtt catcattgcg
    50161 ggaatgcggc gacgcgcgat ggccccaaaa atcactgccg cactgatgcc tgcattgggc
    50221 agcattaagc cgatgcgttc gccttcaaca ctgtattttt caaggatgcg tccaacaaac
    50281 agcgttttcg taagcaattt gcgataggag tctggggtaa agttgacgtc ttcgacacat
    50341 ttcttcccgg ctccgaagcg gtacattgca ctcagtaaag attcgtacag agtttcacgc
    50401 gggcgcaccg ccatacgcgc ttccatcatt atttgatgca gcatttcacc agcgattttg
    50461 cgacggtcac gggcacgcgg cgcatccggc atcgccacct gcgttggtgg caaaatatgc
    50521 agagtaattt gcgggaacaa gcgacgttta accagacctt tcaggcggct gaagtgcgta
    50581 agttccgccc cttcaatacg cacaggaata accgttgcac cagacttcgc cgcgacaaaa
    50641 cccgcgccat cgtagatttt catcagcgag cctgtagtgg tgatgcgtcc ttcagggaaa
    50701 atcaccactg gtcggccctg ttccaccaga cgtaccagat gtttaatagc cataggttgc
    50761 gtcgggtcga gaggaacaaa gtcgataaat gatttcagcc aacgcatata ccactgttgg
    50821 cttattgagg tgtaaacggc aaacactgga cgcacaggta aaaacagtcc aagcaaaatg
    50881 ccatcaataa aagagacgtg attaggcgta attagaacgc gctcgccctt cagtgcctgg
    50941 gtgtcacccg taacgcgaac gcgatacaaa acacggcaca aatttcgaaa aaagctaaaa
    51001 agcattccaa ctccctttgc tctgattcag taaaagcgaa tggagggaga ttacacgaga
    51061 taaagaacgc gagcgacagt aaattaggtg cgaaaaaaaa cctgcgcatc cgcgcaggtt
    51121 ggtgcaagag acagggtacg aagagcgtac cgaataatct caccaatcaa tacctctggg
    51181 atcttgattg tggtctgcac gacgactctt cgccagcgag aaaacgcaaa ggaatgaagg
    51241 gaaatgcaac gaggtgtgta aattgtcggt tactgttaca gattgatgac cggccaaaaa
    51301 aaacctgcgc atctgcgcag gctggtgtaa ttcatgtgct caacccgaag ttgacttcac
    51361 ctatcaatac ctctgggatc accactttag caacctgaag ccaaacgcca ccagcggtca
    51421 atcgcaacag catttcgcaa agtgtaacca aaggtttgca atctcttttt ttgtcttact
    51481 tatttgcgtt tggctcacat tcccacgatg aaaacacgcc accccttgaa ccaacgggcg
    51541 ttttccgtaa cactgaaaga atgtaagcgt ttacccacta aggtattttc atggcgacca
    51601 taaaggatgt agcccgactg gcaggcgttt cagtcgccac cgtttcccgc gtcattaata
    51661 attcacctaa agccagcgaa gcttcccggc tggctgtgca tagtgcaatg gagtctctta
    51721 gctatcaccc gaacgccaac gcccgtgcgc tggcgcagca gaccactgaa acggtcggtc
    51781 tgatcgttgg tgatgtttcc gatccgtttt tcggtgcaat ggtgaaagcg gtcgaacagg
    51841 tggcttatca caccggtaat ttcttattga ttggcaacgg ttaccacaac gaacaaaaag
    51901 agcgtcaggc tattgagcaa ctgatccgcc atcgctgtgc tgcgttggtc gtccatgcca
    51961 aaatgatccc ggatgccgat ttagcctcat taatgaaaca aatgcccggt atggtgctga
    52021 tcaaccgtat cctgcctggc tttgaaaacc gttgtattgc tcttgacgat cgttacggtg
    52081 cctggctggc aacgcgtcat ttaattcagc aaggtcatac ccgcattggt tatctgtgct
    52141 ctaaccactc tatttctgac gccgaagatc gtctgcaagg gtattacgat gcccttgctg
    52201 aaagtggtat tgcggccaat gaccggctgg tgacatttgg cgaaccagac gaaagcggcg
    52261 gcgaacaggc aatgaccgag cttttgggac gaggaagaaa tttcactgcg gtagcctgtt
    52321 ataacgattc aatggcggcg ggtgcgatgg gcgttctcaa tgataatggt attgatgtac
    52381 cgggtgagat ttcgttaatt ggctttgatg atgtgctggt gtcacgctat gtgcgcccgc
    52441 gcctgaccac cgtgcgttac ccaatcgtga cgatggcgac ccaggctgcc gaactggctt
    52501 tggcgctggc ggataatcgc cctctcccgg aaattactaa tgtctttagt ccgacgctgg
    52561 tacgtcgcca ttcagtgtca actccgtcgc tggaggcaag tcatcatgca accagcgact
    52621 aaccgcagtt aaagcaattc cagcgccagt aattcttcga tggtctggcg acggcgaatc
    52681 aaccgcgcct gaccattatc aaacagaact tctggtaaca gcggacggct gttgtagttg
    52741 gatgacattg atgcgccata tgcccctgta tcatgcagta ccagataatc acccgccttc
    52801 acttccggca aggcgcgggt ttcaacattt cccccttcct gctgggtaaa gacatcgccc
    52861 gattcacata atggcccggc gacgacggtt tccaccgttg gcgcgtgttc cagagaacga
    52921 ccatcagctg ccagggcact gatatggtgg taactaccgt acattgccgg gcgcatcaga
    52981 tcgttgaacc cagcatcaac cagcacaaag tggcggctac ccatttgttt gacgctccgc
    53041 acctgagtaa ttaatacgcc agactgcgct accaggaagc gacccggttc aatttccagt
    53101 ttcacagggt ggcccaaatg gcgggcgatt tgctcacgcg cggcattcca cagaccataa
    53161 taatgttcgg tatcaaccgc ctcttcaccc tgttgataag gaacagaaag cccaccgccc
    53221 gcagaaatag cctgtaaatc ctgaccgaat tcgatgacct gacgcaccat agcaccacac
    53281 acctgttcca gatgggcata atcaacgcca gaaccaatgt gcatgtgaat gccgaccagc
    53341 tgcagatgat gacgttgtat cacgtccagt gcggcgggca gatcggtgta ccagataccg
    53401 tgcttgctgt tttcgccacc ggtattggtt ttttggctat gtccgtgacc aaaccccggg
    53461 ttaacgcgca gccatacccg atgccctggc gaaacctggc ccagttggtc gagcatatca
    53521 acagaacccg cattcaccgg aatttgcaat tcactgacgc gttcaagcgt cgcctgatcg
    53581 ataacatctg ccgtaaaaac aatatcatcg gggtgcgttt gcggattgta acccgccgcc
    53641 aacgcacgct ctatttcgcc taacgagacg gaatccactt tcacgccctg ctcacgcatt
    53701 aagcgcaaaa tatgaatatt ggaacaggct ttctgtgcaa agcgcaccac atcaaactgt
    53761 ttcagcgctg caatctgccg acgaataatt tgcgcatcgt agacccacac cgggcagcca
    53821 aattcagcgg gcaaacgcag cagattttcg gcggtgagat cggtatcggt gctgaacagt
    53881 gaatgtggca taacaaactc cagatgagtg cttttttatg attacgccac atcataaaaa
    53941 gaataaaaaa tatcgattta tgtcgagtct atgcaaaaat gatatggatt accggattgc
    54001 gagagagcgc taatggccgc cgttaactta cgtcatattg aaatttttca tgcggtaatg
    54061 accgccggaa gcctgactga ggcagcacac ctgctacaca cctcacagcc aaccgtcagc
    54121 cgcgaactgg cgcgctttga gaaggtgatc gggctaaaat tgtttgagcg cgtacgtgga
    54181 cgattacatc ctaccgtgca aggactgcgt ctgtttgaag aagtgcaacg atcctggtac
    54241 ggactggatc gcattgtcag cgccgcagaa agtctgcgcg agtttcgcca gggagaactg
    54301 tctattgcct gcctgccggt cttttcgcaa tcttttttac cgcagctcct gcaacccttt
    54361 ctggcacgtt atcccgatgt cagcttaaat atcgtgcccc aggaatcacc gctacttgaa
    54421 gagtggctct cggcccagcg tcatgattta ggactcactg agacactcca tacgcctgcg
    54481 ggaacagaac gtaccgaatt actctcttta gatgaagtgt gtgtgttacc tccgggtcat
    54541 ccgctggcgg taaaaaaggt attaacgccg gatgattttc agggtgagaa ctacatcagc
    54601 ctttcccgta ctgacagcta tcgccagttg ctggatcagc tatttactga acatcaggtt
    54661 aaacgacgca tgatcgtaga aacccacagc gccgcgtcag tctgcgcaat ggtacgggcg
    54721 ggggtaggtg tttcggtggt taacccgctc accgcactgg attatgcggc aagcggttta
    54781 gtggtgcggc ggttcagtat tgcggttccg ttcaccgtca gcctgatccg ccccctgcac
    54841 cgcccgtcat cagcgctggt gcaggcgttt agtgagcatt tacaagcggg gttaccgaaa
    54901 ctggtcactt ctcttgacgc gattttgtcg tcagctacga cagcataaaa gcgacagcat
    54961 cctcggcatg gatcgccgcg gtatcaaaca caggcaaaac actgcgctct tctggcacca
    55021 gtaaaccaat ttctgtgcag ccaaaaatga cgccctgtgc gccctgttct gcaaggcgag
    55081 caatcacttg cgcataataa gcgcgtgacg cttcggtaaa ttgccccaga cacagttctt
    55141 caaaaataat ctgattaatt ttcgcccgtt catccgcttc aggaataaga caattgatgg
    55201 aaaattgttc cgtcagccgc ccgcgataaa aatcctgttc catggtgtaa cgcgtaccca
    55261 gcagcgccac acgagtcatt ccggccccgg taattgcacg tccggtggca tccgcaatgt
    55321 gtaagaaagg cagagtgcaa cgtgactcaa tggcatccgc cactttatgc atcgtattgg
    55381 tacataacac aataccttct gcgcccgccc gctgtaagcc aagcgccgcc tcagccagaa
    55441 tgtccccggt tttatcccat tccccgcgac gctggcactc ttctatttca tgaaaatcga
    55501 cgctatgtag cagcacttgc gcagagtgaa gcccaccaag ccgctgttta atgccttcat
    55561 ttatcagacg atagtaagga atggtggatt cccagctcat tcctcccagc aaaccaattg
    55621 ttttcattcc tctctcctga tgtgtgttac cgcaacaagg ctgaataagg aacgagacaa
    55681 acgcctcaac ggccaggtgc ccgatctcta ttaacgaaaa aagggccgga tgtacagcac
    55741 atccggcccg tgaaatcaga cgccgatatt tctcaacttc tcgcctgcca tcagtttgcg
    55801 ttcgatatgt tccagcgtga catttttggt ttccggaatg agccagaaag tgatgcccac
    55861 aaacgcaatg ttcagcgcag tgtagagcca gaacgtaccg gcagcgccaa tgctatcaag
    55921 cagtgtcagg aaggtcgcgc cgataatcat attcgacacc cagtttgtcg tcgtcgaaca
    55981 ggtaataccg aaatcgcggc atttcagcgg ctgaatttca gagcacagga tccacaccac
    56041 tggcgcggcg ctcatcgcat aaccggcaat acacatcatc gtcatgccaa cagagagcca
    56101 ggacaagcca ctggaagccg taccgttatc aaactgcatc aggcaatagc ccagcaccag
    56161 agtgcctaac gccatcacgc tgaaaccaat tttcagagcc ggtttacgac ctgctttatc
    56221 taccgtaaag accgcaatga aggtcgcgaa cataaaggtc agtcccacga ccagagtcgc
    56281 aatcatctgt tgttctgtgg tcgtaaagcc cgccattttg aagatacgcg gcgcatagta
    56341 catgatgatg ttcataccgg taaactgctg catcgcctgc aacaacatac cgagaaacac
    56401 agcacgacgg acgttacggt tgatcttaaa cagtgcccaa ccgccttgtt ttaacttcag
    56461 gctttcacga atttcgttga gttcttctcg cgctttttcc gacgtatcgc gcagcatacg
    56521 caacacttct tccgcctcaa tatgacgccc cttttccgcc agccagcgcg ggctatttgg
    56581 caggaagacc accagaataa tcagcaggac tgctggtaaa gcaagaaccc ccaacattgc
    56641 gcgccagtta ccgctataac tgaacgctgt atcggataaa aacgccagca cgatgccgag
    56701 tgtgaccatc aactggtaca tactgatcat cttaccgcga acgttttcac ttgccatttc
    56761 agaaagatac agaggagcgg tgtaagacgc gatcccgaca gcaatgccca gcaccacacg
    56821 agcggcgatt aacatctcta cgctggtcgc aaaagcggac cctatagaac cgagtacaaa
    56881 caggatggcc cccgccatca ggctgtattt acgacccagg cggaacgaca gccaaccatt
    56941 aaacagcgca ccaattgctg cgccgagcat catgctacta accacccatt cctgcaaacg
    57001 actggtcagc acaaagtgat cggtaatgaa cggcaacgct ccggcgatta cgccgatatc
    57061 aagaccaaat aacaatcctg cgaccgcagc agctaccgaa acaaacatat tcatacgccg
    57121 cgtatcccgc aaagaacgtg gcgttaaagc agattccgta ttgatagtaa ccattttttc
    57181 ctgccagcag agagtaagac atagtgaaaa aatacgtgaa caactcacgc aggtgtcagg
    57241 tcggaaacag cataaatatg gattaaattg ctacgacatg tcgttatgtg atggatattc
    57301 caattttcaa attaagttga attattgata ttattattaa ccacctaatt ttacagcaga
    57361 ta
//
LOCUS       DAPGUL010000018        57175 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.018, whole genome shotgun sequence.
ACCESSION   DAPGUL010000018 DAPGUL010000000
VERSION     DAPGUL010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 57175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57175
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.018"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            62..505
                     /gene="cmtB"
                     /locus_tag="RHX21_001214"
     CDS             62..505
                     /gene="cmtB"
                     /locus_tag="RHX21_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IIA"
                     /protein_id="HDV1986435.1"
                     /translation="MRLSDYFPESSISVIHSAKDWQEAIDFSMVSLLDKNYISENYIQ
                     AIKDSTINNGPYYILAPGVAMPHARPECGALKTGMSLTLLEQGVYFPGNDEPIKLLIG
                     LSAADADSHIGAIQALSELLCEEEILEQLLTASSEKQLADIISRG"
     gene            533..1921
                     /gene="cmtA"
                     /locus_tag="RHX21_001215"
     CDS             533..1921
                     /gene="cmtA"
                     /locus_tag="RHX21_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HDV1986436.1"
                     /translation="MENKSARAKVQAFGGFLTAMVIPNIGAFIAWGFITALFIPTGWL
                     PNEHFAKIVGPMITYLLPVMIGSTGGHLVGGKRGAVMGGIGTIGVIVGAEIPMFLGSM
                     IMGPLGGLVIKYVDKALEKRIPAGFEMVINNFSLGIAGMLLCLLGFEVIGPAVLIANT
                     FVKECIEALVHAGYLPLLSVINEPAKVLFLNNAIDQGVYYPLGMQQASVNGKSIFFMV
                     ASNPGPGLGLLLAFTLFGKGMSKRSAPGAMIIHFLGGIHELYFPYVLMKPLTIIAMIA
                     GGMSGTWMFNLLDGGLVAGPSPGSIFAYLALTPKGSFLATIAGVTVGTLVSFAITSLI
                     LKMEKTVETESEDEFAQSANAVKAMKQEGAFSLSRVKRIAFVCDAGMGSSAMGATTFR
                     KRLEKAGLAIEVKHYAIENVPADADIVVTHASLEGRVKRVTDKPLILINNYIGDPKLD
                     TLFNQLTAEHKH"
     gene            1936..3213
                     /locus_tag="RHX21_001216"
     CDS             1936..3213
                     /locus_tag="RHX21_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HDV1986437.1"
                     /translation="MKTKVAAIYGKRDVRLREFELPEITDNELLVSVISDSVCLSTWK
                     AALLGSEHKRVPDDLENHPVITGHECAGVIVEVGKNLTGKYKKGQRFVLQPAMGLPSG
                     YSAGYSYEYFGGNATYMIIPEIAINLGCVLPYHGSYFAAASLAEPMCCIIGAYHANYH
                     TTQYVYEHRMGVKPGGNIALLACAGPMGIGAIDYAINGGIQPSRVVVVDIDDKRLAQV
                     QKLLPVDLAASKGIELVYVNTKGMSDPVQTLRALTGDVGFDDIFVYAAVPAVVEMADE
                     LLAEDGCLNFFAGPTDKNFKVPFNFYNVHYNSTHVVGTSGGSTDDMKEAIALSATGQL
                     QPSFMVTHIGGLDAVPDTVLNLPDIPGGKKLIYNGVTMPLTAIADFAEKGKTDPLFKE
                     LARLVEETHGIWNEQAEKYLLAQFGVDIGEAAQ"
     gene            3210..4175
                     /gene="yggF"
                     /locus_tag="RHX21_001217"
     CDS             3210..4175
                     /gene="yggF"
                     /locus_tag="RHX21_001217"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphatase"
                     /protein_id="HDV1986438.1"
                     /translation="MMSLAWPLFRVTEQAALAAWPQTGCGDKNKIDGLAVTAMRQALN
                     DVAFRGRVVIGEGEIDHAPMLWIGEEVGKGDGPEVDIAVDPIEGTRMVAMGQSNALAV
                     MAFAPRDSLLHAPDMYMKKLVVNRLAAGAIDLSLPLADNLRNVARALGKPLDKLRMVT
                     LDKPRLSAAIEEATQLGVKVFALPDGDVAASVLTCWQDNPYDVMYTIGGAPEGVISAC
                     AVKALGGDMQAELIDFCQAKGDYTENRQIAEQERKRCKAMGVDVNRVYSLDELVRGND
                     ILFSATGVTGGELVNGIQQTANGVRTQTLLIGGADQTCNIIDSLH"
     gene            4197..4706
                     /gene="fumE"
                     /locus_tag="RHX21_001218"
     CDS             4197..4706
                     /gene="fumE"
                     /locus_tag="RHX21_001218"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarase E"
                     /protein_id="HDV1986439.1"
                     /translation="MATLTEDDVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVD
                     NDEEIVEYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQYWHYLNEQD
                     ETPGFADDMTWDFISNVNSITCNATLYDALKAMKFADFAVWSEARFSGMVKTALTLAV
                     TTTLKELTP"
     gene            4703..5416
                     /locus_tag="RHX21_001219"
                     /pseudo
     CDS             4703..5416
                     /locus_tag="RHX21_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708692.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside/nucleotide kinase family protein"
     gene            complement(5388..6065)
                     /locus_tag="RHX21_001220"
     CDS             complement(5388..6065)
                     /locus_tag="RHX21_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708691.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/molybdate ABC transporter ATP-binding
                     protein"
                     /protein_id="HDV1986440.1"
                     /translation="MLTLNKISYRWPGAATDCLCDISLQLKQGEWLALTGDNGAGKST
                     LLRVMAGLLTPTAGTVMLQQQAMKNLKNRQRAAKVGVLFQEAENQLFHSTVADEIAFG
                     LKLQKCPADEITQRTHAALQCCQLADTANSHPLDLHSAQRRMVAVACLEALSPPLLLL
                     DEPSRDFDENWLSVFESWLEKCGQRGTSVVAISHDAAFTRRHFSRVVRLEDGLIRNVN
                     PPDDIHP"
     gene            complement(6059..6736)
                     /locus_tag="RHX21_001221"
     CDS             complement(6059..6736)
                     /locus_tag="RHX21_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDV1986441.1"
                     /translation="MVTLEQFRYCPTHSTHPPFCYDFHYVKPGMVAIFGDNGSGKSTL
                     AQLMAGWYPDFLPGEITGTGTLLGTPIGHLPLNEQSATIQLVQQSPYLQLSGCTFSVE
                     EEVAFGPENLCLAEAEIMARIDAALTLTECQPLRHRHPATLSGGETQRVVIACAIAMQ
                     PKLLILDEAFSRLTPQASEMLLQRLQHWAFERGSLIILFERHRTPFLNYCQQAWQLQN
                     GALQPLC"
     gene            complement(6724..7431)
                     /locus_tag="RHX21_001222"
     CDS             complement(6724..7431)
                     /locus_tag="RHX21_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDV1986442.1"
                     /translation="MHPFTSLTLWALAACTTLILPAQTILPIYSAATFFCLIALKATR
                     RRAKYVVWLMFSLGAGLWLVHGGWLPEWLSGTPRSPERWSHAITLWLRILAIVSTSQL
                     WMQYVPVQCFIRALFASRLPPGVAYLFAGPLLVVEQLKRQLAIIHEAQRARGVPLDEG
                     WYQRLRAMPALIIPLTHNALNDLAVRGAALDMRAFRIHNRRTTLWAPADSTLQRVARY
                     TMILLMLTEFGAWIWLR"
     gene            complement(7432..8010)
                     /locus_tag="RHX21_001223"
     CDS             complement(7432..8010)
                     /locus_tag="RHX21_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDV1986443.1"
                     /translation="MARSHFSSQALVLIVISIAINMIGGQLASMVKLPIFLDSIGTLI
                     SAVLLGPVIGMLTGLLTNLLWGLLTNPIAAAFAPVAMVIGLVAGCLARAGWFRTLPKV
                     VVSGVIITLAVTVVAVPLRTALFGGVTGSGADLFVAWMHSMGQNLVESVAITVIGANL
                     VDKILTAVIVWLLLRQLPIRTTRHFPAMAAVR"
     gene            complement(8033..8464)
                     /locus_tag="RHX21_001224"
     CDS             complement(8033..8464)
                     /locus_tag="RHX21_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDV1986444.1"
                     /translation="MMTLPYPYSSSARFYALRLLPGQEVFSQLHAFAQQHQLHAAWIA
                     GCTGSLTDVALRYAGQEGTTLLNGTFEVISLNGTLEQSGEHLHLCVSDPHGTMLGGHM
                     MPGCTVRTTLELVIGSLEELAFSRQPCALSGYDELHISPVK"
     gene            8836..9855
                     /gene="epd"
                     /locus_tag="RHX21_001225"
     CDS             8836..9855
                     /gene="epd"
                     /locus_tag="RHX21_001225"
                     /EC_number="1.2.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="erythrose-4-phosphate dehydrogenase"
                     /protein_id="HDV1986445.1"
                     /translation="MTVRVAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGM
                     AHLLKYDTSHGRFAWEVRQERDQLFVGDDAIRVLHERSLQSLPWRELGVDVVLDCTGV
                     YGSREHGEAHIAAGAKKVLFSHPGSNDLDATVVYGVNQDQLRAEHRIVSNASCTTNCI
                     IPVIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAG
                     ITRFFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKANEVNLLLQKAAQGAFHGIV
                     DYTELPLVSVDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMA
                     TVAFR"
     gene            9905..11068
                     /gene="pgk"
                     /locus_tag="RHX21_001226"
     CDS             9905..11068
                     /gene="pgk"
                     /locus_tag="RHX21_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HDV1986446.1"
                     /translation="MSVIKMTDLDLAGKRVFIRADLNVPVKDGKVTSDARIRASLPTI
                     ELALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKDKLSNPVRLVKDYLDGVDVA
                     EGELVVLENVRFNKGEKKDDETLSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFADV
                     ACAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIA
                     NTFIAAQGHDVGKSLYEADLVDEAKRLLTTCNIPVPSDVRVATEFSETAPATLKSVND
                     VKADEQILDIGDASAQELAEILKNAKTILWNGPVGVFEFPNFRKGTEIVANAIADSEA
                     FSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLEERAKK"
     gene            11283..12362
                     /gene="fbaA"
                     /locus_tag="RHX21_001227"
     CDS             11283..12362
                     /gene="fbaA"
                     /locus_tag="RHX21_001227"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HDV1986447.1"
                     /translation="MSKIFDFVKPGVITGDDVQKVFQVAKENNFALPAVNCVGTDSIN
                     AVLETAAKVKAPVIVQFSNGGASFIAGKGVKSDVPQGAAILGAISGAHHVHQMAEHYG
                     VPVILHTDHCAKKLLPWIDGLLDAGEKHFAATGKPLFSSHMIDLSEESLQENIEICSK
                     YLERMSKIGMTLEIELGCTGGEEDGVDNSHMDASALYTQPEDVDYAYTELSKISPRFT
                     IAASFGNVHGVYKPGNVVLTPTILRDSQEYVSKKHNLPHNSLNFVFHGGSGSTAQEIK
                     DSVSYGVVKMNIDTDTQWATWEGVLNYYKANEAYLQGQLGNPKGEDQPNKKYYDPRVW
                     LRAGQTSMIARLEKAFQELNAIDVL"
     gene            12720..13580
                     /gene="mscS"
                     /locus_tag="RHX21_001228"
     CDS             12720..13580
                     /gene="mscS"
                     /locus_tag="RHX21_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small-conductance mechanosensitive channel MscS"
                     /protein_id="HDV1986448.1"
                     /translation="MEDLNVVDSINGAGSWLVANQALLLSYAVNIVAALAIIIVGLII
                     ARMISNAVNRLMISRKIDATVADFLSALVRYGIIAFTLIAALGRVGVQTASVIAVLGA
                     AGLAVGLALQGSLSNLAAGVLLVMFRPFRAGEYVDLGGVAGTVLSVQIFSTTMRTADG
                     KIIVIPNGKIIAGNIINFSREPVRRNEFIIGVAYDSDIDQVKQILTNIIQSEDRILKD
                     REMTVRLNELGASSINFVVRVWSNSGDLQNVYWDVLERIKREFDAAGISFPYPQMDVN
                     FKRVKEDKAA"
     gene            13719..14354
                     /gene="argO"
                     /locus_tag="RHX21_001229"
     CDS             13719..14354
                     /gene="argO"
                     /locus_tag="RHX21_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine exporter ArgO"
                     /protein_id="HDV1986449.1"
                     /translation="MFSYYFQGLALGAAMILPLGPQNAFVMNQGIRRQYHIMIALLCA
                     ISDLVLICAGIFGGSALLMQSPWLLALVTWGGVVFLLWYGFGAFKTAMSSNIELASAE
                     VLKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLDVEPKRWFALGTISASFLWF
                     FGLAILAAWLAPRLRTAKSQRIINLVVGCVMWFIALQLARDGIAHAQALFS"
     gene            14447..15187
                     /locus_tag="RHX21_001230"
     CDS             14447..15187
                     /locus_tag="RHX21_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative stress defense protein"
                     /protein_id="HDV1986450.1"
                     /translation="MKFKVIALAALMGISGMAAQANELPDGPHIVTSGTASVDAVPDI
                     ATLAIEVNVAAKDAATAKKQADERVAQYISFLELNQIAKKDISSANLRTQPDYDYQDG
                     KSILKGYRAVRTVEVTLRQLDKLNSLLDGALKAGLNEIRSVSLGVAQPDAYKDKARKA
                     AIDNAIHQAQELANGFHRKLGPVYSVRYHVSNYQPSPMVRMMKADAAPVSAQETYEQA
                     AIQFDDQVDVVFQLEPVDQQPAKTPAAQ"
     gene            15354..16250
                     /locus_tag="RHX21_001231"
     CDS             15354..16250
                     /locus_tag="RHX21_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417396.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV1986451.1"
                     /translation="MDIFISKKMRNFILLAQTNNIARAAEKIHMTASPFGKSIAALEE
                     QIGYTLFTRKDNNISLNKAGQELYQKLFPVYQRLSAIDNEIHNSGRRSREIVIGIDNT
                     YPTIIFDQLISLGDKYEGVTAQPVEFSENGVIDNLFDRQLDFIISPQHVSARVQELEN
                     LTISELPPLRLGFLVSRRYEERQEQELLQELPWLQMRFQNRANFEAMIDANMRPCGIN
                     PTIIYRPYSFMAKISAVERGHFLTVIPHFAWRLVNPATLKYFDAPHRPMYMQEYLYSI
                     RNHRYTATMLQHIAEDRDGTNH"
     gene            complement(16247..17725)
                     /gene="scpC"
                     /locus_tag="RHX21_001232"
     CDS             complement(16247..17725)
                     /gene="scpC"
                     /locus_tag="RHX21_001232"
                     /EC_number="2.8.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionyl-CoA:succinate CoA transferase"
                     /protein_id="HDV1986452.1"
                     /translation="METQWTRMTADEAAEIIQHNDMVAFSGFTPAGSPKALPTAIARR
                     ANEQHEAKKPYQIRLLTGASISAAADDVLSDADAVSWRAPYQTSSGLRKKINQGAVSF
                     VDLHLSEVAQMVNYGFFGDIDVAVIEASALAPDGRVWLTSGIGNAPTWLLRAKKVIIE
                     LNHYHDPRVAELADIVIPGAPPRRNSVSIFHAMDRVGTRYVQIDPKKIVAVVETNLPD
                     AGNMLDKQNPMCQQIADNVVTFLLQEMAHGRIPPEFLPLQSGVGNINNAVMARLGENP
                     EIPPFMMYSEVLQESVVHLLETGKISGASASSLTISADSLRKIYDNMDYFASRIVLRP
                     QEISNNPEIIRRLGVIALNVGLEFDIYGHANSTHVAGVDLMNGIGGSGDFERNAYLSI
                     FMAPSIAKEGKISTVVPMCSHVDHSEHSVKVIITEQGIADLRGLSPLQRARTIIDNCA
                     HPMYRDYLHRYLENAPGGHIHHDLSHVFDLHRNLIATGSMLG"
     gene            complement(17749..18534)
                     /gene="scpB"
                     /locus_tag="RHX21_001233"
     CDS             complement(17749..18534)
                     /gene="scpB"
                     /locus_tag="RHX21_001233"
                     /EC_number="7.2.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311816.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl-CoA decarboxylase"
                     /protein_id="HDV1986453.1"
                     /translation="MSYQYVNVVTINKVAVIEFNYGRKLNALSKVFIDDLMQALSDLN
                     RPEIRCIILRAPSGSKVFSAGHDIHELPSGGRDPLSYDDPLRQITRMIQKFPKPIISM
                     VEGSVWGGAFEMIMSSDLIIAASTSTFSMTPVNLGVPYNLVGIHNLTRDAGFHIVKEL
                     IFTASPITAQRALAVGILNHVVEVEELEDFTLQMAHHISEKAPLAIAVIKEELRVLGE
                     AHTMNSDEFERIQGMRRAVYDSEDYQEGMNAFLEKRKPNFVGH"
     gene            complement(18545..19540)
                     /gene="meaB"
                     /locus_tag="RHX21_001234"
     CDS             complement(18545..19540)
                     /gene="meaB"
                     /locus_tag="RHX21_001234"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl Co-A mutase-associated GTPase
                     MeaB"
                     /protein_id="HDV1986454.1"
                     /translation="MINEATLAESIRRLRQGERATLAQAMTLVESRHPSHQALSTQLL
                     DAIMPYCGNALRLGVTGTPGAGKSTFLEAFGMLLIREGLKVAVIAVDPSSPVTGGSIL
                     GDKTRMNDLARAEAAFIRPVPSSGHLGGASQRARELMLLCEAAGYDVVIVETVGVGQS
                     ETEVARMVDCFISLQIAGGGDDLQGIKKGLMEVADLLVINKDDGDNHTNVAIARHMYE
                     SALHILRRKYDEWQPRVLTCSALEKRGIDEIWHAIIDFKTALTASGRLQQVRQQQSVE
                     WLRKQTEEEVLHHLFANEDFDRYYRQTLLAVKNNTLSPRTGLRQLSEFIQTQYFD"
     gene            complement(19533..21677)
                     /gene="scpA"
                     /locus_tag="RHX21_001235"
     CDS             complement(19533..21677)
                     /gene="scpA"
                     /locus_tag="RHX21_001235"
                     /EC_number="5.4.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl-CoA mutase"
                     /protein_id="HDV1986455.1"
                     /translation="MSNEQEWQQLANKELSRREKTVDSLVQQTAEGIAIKPLYTEADL
                     DNLEVTGTLPGLPPYVRGPRATMYTAQPWTIRQYAGFSTAKESNAFYRRNLAAGQKGL
                     SVAFDLATHRGYDSDNPRVAGDVGKAGVAIDTVEDMKVLFDQIPLDKMSVSMTMNGAV
                     LPVLAFYIVAAEEQGVTPDKLTGTIQNDILKEYLCRNTYIYPPKPSMRIIADIIAWCS
                     GNMPRFNTISISGYHMGEAGANCVQQVAFTLADGIEYIKAAISAGLKIDDFAPRLSFF
                     FGIGMDLFMNVAMLRAARYLWSEAVSGFGAQDPKSLALRTHCQTSGWSLTEQDPYNNV
                     IRTTIEALAATLGGTQSLHTNAFDEALGLPTDFSARIARNTQIIIQEESELCRTVDPL
                     AGSYYIESLTDQIVKQARAIIQQIDEAGGMAKAIEAGLPKRMIEEASAREQSLIDQGK
                     RVIVGVNKYKLDHEDETDVLEIDNVMVRNEQIASLERIRATRDDAAVTAALNALTHAA
                     QHNENLLAAAVNAARVRATLGEISDALEVAFDRYLVPSQCVTGVIAQSYHQSEKSASE
                     FDAIVAQTEQFLADNGRRPRILIAKMGQDGHDRGAKVIASAYSDLGFDVDLSPMFSTP
                     EEIARLAVENDVHVVGASSLAAGHKTLIPELVEALKKWGREDICVVAGGVIPPQDYAF
                     LQERGVAAIYGPGTPMLESVRDVLNLISQHHD"
     gene            complement(21881..22774)
                     /gene="argP"
                     /locus_tag="RHX21_001236"
     CDS             complement(21881..22774)
                     /gene="argP"
                     /locus_tag="RHX21_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator ArgP"
                     /protein_id="HDV1986456.1"
                     /translation="MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLEN
                     MFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSL
                     ATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLG
                     ALDYLFVSSKPFAEKYFPNGVTRSALLKAPVVAFDHLDDMHQAFLQQNFDLPPGSVPC
                     HIVNSSEAFVQLARQGTTCCMIPHLQIEKELASGELIDLTPGLFQRRMLYWHRFAPES
                     RMMRKVTDALLDYGHKVLRQD"
     gene            22916..23101
                     /locus_tag="RHX21_001237"
     CDS             22916..23101
                     /locus_tag="RHX21_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001328908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986457.1"
                     /translation="MHFAQRVRALVVLNGVALLPLFAPWSGIPRPLYALFAGRKGMPA
                     IARYFMDELTTRLANGV"
     gene            23157..23816
                     /gene="rpiA"
                     /locus_tag="RHX21_001238"
     CDS             23157..23816
                     /gene="rpiA"
                     /locus_tag="RHX21_001238"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HDV1986458.1"
                     /translation="MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKG
                     QIEGAVSSSDASTEKLKSLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAALTR
                     EKIIASVAEKFICIADASKQVDILGKFPLPVEVIPMARSAVARQLVKLGGRPEYRQGV
                     VTDNGNVILDVHGMEILDPIAMENAINAIPGVVTVGLFANRGADVALIGTPDGVKTIV
                     K"
     gene            24072..25304
                     /gene="serA"
                     /locus_tag="RHX21_001239"
     CDS             24072..25304
                     /gene="serA"
                     /locus_tag="RHX21_001239"
                     /EC_number="1.1.1.95"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HDV1986459.1"
                     /translation="MAKVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDD
                     EQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVF
                     NAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYG
                     HIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTK
                     NMMGAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDP
                     FTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPL
                     HGGRRLMHIHENRPGVLTALNKIFAEQGVNIAAQYLQTSAQMGYVVIDIEADEDVAEK
                     ALQAMKAIPGTIRARLLY"
     gene            25533..25592
                     /gene="ibsC"
                     /locus_tag="RHX21_001240"
     CDS             25533..25592
                     /gene="ibsC"
                     /locus_tag="RHX21_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin IbsC"
                     /protein_id="HDV1986460.1"
                     /translation="MMRLVIILIVLLLISFGAY"
     gene            25925..25984
                     /locus_tag="RHX21_001241"
     CDS             25925..25984
                     /locus_tag="RHX21_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HDV1986461.1"
                     /translation="MMRLAIILIVLLLISFPAY"
     gene            complement(26085..26687)
                     /locus_tag="RHX21_001242"
     CDS             complement(26085..26687)
                     /locus_tag="RHX21_001242"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311809.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HDV1986462.1"
                     /translation="MTQLPELPLTLSRQEIRKMIRQRRRALTPEQQQEMGQQAATRMM
                     TYPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAGKRVYLPVLHPFSAGNLLFLNYHPQ
                     SELVMNRLKIHEPKLDVRDVLPLSRLDVLITPLVAFDEYGQRLGMGGGFYDRTLQNWQ
                     HYKTQPVGYAHDCQLVEKLPVEEWDIPLPAVVTPSKVWEW"
     gene            complement(26708..26891)
                     /gene="ssrS"
                     /locus_tag="RHX21_001243"
     ncRNA           complement(26708..26891)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="RHX21_001243"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(26933..27262)
                     /gene="zapA"
                     /locus_tag="RHX21_001244"
     CDS             complement(26933..27262)
                     /gene="zapA"
                     /locus_tag="RHX21_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HDV1986463.1"
                     /translation="MSAQPVDIQIFGRSLRVNCPPDQRDALNQAADDLNQRLQDLKER
                     TRVTNTEQLVFIAALNISYELAQEKAKTRDYAASMEQRIRMLQQTIEQALLEQGRITE
                     KTNQNFE"
     gene            27430..28008
                     /gene="ygfB"
                     /locus_tag="RHX21_001245"
     CDS             27430..28008
                     /gene="ygfB"
                     /locus_tag="RHX21_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708672.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0149 family protein YgfB"
                     /protein_id="HDV1986464.1"
                     /translation="MSIQNEMPGYNEMNQYLNQQGTGLTPAEMHGLISGMICGGNDDS
                     SWLPLLHDLTNEGMAFGHELAQALRKMHSGTSDALQDDGFLFQLYLPDGDDVSVFDRA
                     DALAGWVNHFLLGLGVTQPKLDKVTGETGEAIDDLRNIAQLGYDEDEDQEELEMSLEE
                     IIEYVRVAALLCHDTFTHPQPTAPEVQKPTLH"
     gene            28034..29359
                     /gene="pepP"
                     /locus_tag="RHX21_001246"
     CDS             28034..29359
                     /gene="pepP"
                     /locus_tag="RHX21_001246"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro aminopeptidase"
                     /protein_id="HDV1986465.1"
                     /translation="MSEISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPY
                     RQNSDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWFGRRLGQDAAPEK
                     LGVDRALAFSEINQQLYQLLNGLDVVYHAQGEYAYADEIVNSALEKLRKGSRQNLTAP
                     ATMIDWRPVVHEMRLFKSPEEIAVLRRAGEITALAHTRAMEKCRPGMFEYHLEGEIHH
                     EFNRHGARYPSYNTIVGSGENGCILHYTENECELRDGDLVLIDAGCEYKGYAGDITRT
                     FPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSMQEVTGEVVRIMVSGLVKLGILKG
                     DVDELIAQNAHRPFFMHGLSHWLGLDVHDVGVYGQDRSRILEPGMVLTVEPGLYIAPD
                     ADVPEQYRGIGIRIEDDIVITETGNENLTASVVKKPEEIEALMAAARKQ"
     gene            29356..30534
                     /gene="ubiH"
                     /locus_tag="RHX21_001247"
                     /gene_synonym="visB"
     CDS             29356..30534
                     /gene="ubiH"
                     /locus_tag="RHX21_001247"
                     /gene_synonym="visB"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-octaprenyl-6-methoxyphenyl hydroxylase"
                     /protein_id="HDV1986466.1"
                     /translation="MSVIIVGGGMAGATLALAISRLSHGALPVHLIEATAPESHAHPG
                     FDGRAIALAAGTCQQLARIGVWQSLADCATAITTVHVSDRGHAGFVTLAAEDYQLAAL
                     GQVVELHNVGQRLFALLRKAPGVTLHCPDRVANVARTQSHVEVTLESGETLTGRVLVA
                     ADGTHSALATACGVDWQQEPYEQLAVIANVATSVAHEGRAFERFTQHGPLAMLPMSDG
                     RCSLVWCHPLERREELLSWSDEKFCRELQSAFGWRLGKITHAGKRSAYPLALTRAARA
                     ITHRTVLVGNAAQTLHPIAGQGFNLGMRDVMSLAETLTQAHERGEDIGDYGILCRYQQ
                     RRQSDREATIGVTDSLVHLFANRWAPLVVGRNIGLMTMELFTPARDVLAQRTLGWVAR
                     "
     gene            30557..31759
                     /gene="ubiI"
                     /locus_tag="RHX21_001248"
                     /gene_synonym="visC"
     CDS             30557..31759
                     /gene="ubiI"
                     /locus_tag="RHX21_001248"
                     /gene_synonym="visC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent 2-octaprenylphenol hydroxylase"
                     /protein_id="HDV1986467.1"
                     /translation="MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLAADA
                     PPQLRVSAINAASEKLLTRLGVWQDILSRRASCYHGMEVWDKDSFGHISFDDQSMGYS
                     HLGHIVENSVIHYALWSKAQQASDITLLAPAELQQVAWGENETFLTLKDGSMLTARLV
                     IGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDAVARQVFHGEGILAFLPLS
                     DPHLCSIVWSLSPEEAQRMQQASEDEFNRALNIAFDNRLGLCKVESARQVFPLTGRYA
                     RQFAAHRLALVGDAAHTIHPLAGQGVNLGFMDAAELIAELKRLHRQGKDIGQYIYLRR
                     YERSRKHSSALMLAGMQGFRDLFSGTNPAKKLLRDIGLKLADTLPGVKPQLIRQAMGL
                     NDLPEWLR"
     gene            complement(31833..31916)
                     /locus_tag="RHX21_001249"
     CDS             complement(31833..31916)
                     /locus_tag="RHX21_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986468.1"
                     /translation="MSKNTKSKNHGIRKYNAKTEVKLVYFK"
     gene            32206..33300
                     /gene="gcvT"
                     /locus_tag="RHX21_001250"
     CDS             32206..33300
                     /gene="gcvT"
                     /locus_tag="RHX21_001250"
                     /EC_number="2.1.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system aminomethyltransferase
                     GcvT"
                     /protein_id="HDV1986469.1"
                     /translation="MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQIDEHHAVRTDA
                     GMFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVY
                     YFTEDFFRLVVNSATREKDLSWITQHAEPFGIEITVRDDLSMIAVQGPNAQAKAATLF
                     NDAQRQAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIALPNEKAADFWRALVEAGVKP
                     CGLGARDTLRLEAGMNLYGQEMDETISPLAANMGWTIAWEPADRDFIGREALEVQREH
                     GTEKLVGLVMTEKGVLRNELPVRFTDAQGNQHEGIITSGTFSPTLGYSIALARVPEGI
                     GETAIVQIRNREMPVKVTKPVFVRNGKAVA"
     gene            33324..33713
                     /gene="gcvH"
                     /locus_tag="RHX21_001251"
     CDS             33324..33713
                     /gene="gcvH"
                     /locus_tag="RHX21_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HDV1986470.1"
                     /translation="MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVD
                     LPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWI
                     FKIKASDESELESLLDATAYEALLEDE"
     gene            33832..36705
                     /gene="gcvP"
                     /locus_tag="RHX21_001252"
     CDS             33832..36705
                     /gene="gcvP"
                     /locus_tag="RHX21_001252"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase"
                     /protein_id="HDV1986471.1"
                     /translation="MTQTLSQLENSGAFIERHIGPDAAQQQEMLNAVGAQSLNALTGQ
                     IVPKDIQLATPPQVGAPATEYAALAELKAIASRNKRFTSYIGMGYTAVQLPPVILRNM
                     LENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAM
                     AKRVSKLKNANRFFVASDVHPQTLDVVRTRAETFGFEVIVDDAQKVLDHQDVFGVLLQ
                     QVGTTGEIHDYTALISELKSRKIVVSVAADIMALVLLTAPGKQGADIVFGSAQRFGVP
                     MGYGGPHAAFFAAKDEYKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNI
                     CTSQVLLANIASLYAVYHGPVGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLC
                     VEVADKAGVLARAEAAEINLRSDILNAVGITLDETTTRENVMQLFSVLLGDNHGLEID
                     TLDKDVAHDSRSIQPAMLRDDEILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIP
                     LGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAEGYQQMIAQLADWLVKLTGYDAVC
                     MQPNSGAQGEYAGLLAIRHYHESRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVAC
                     DKNGNIDLTDLRAKAEQAGDNLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDG
                     ANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVV
                     QIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKKASQVAILNANYIASRLQD
                     AFPVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLM
                     VEPTESESKVELDRFIDAMLAIRAEIDQVKAGVWPLEDNPLVNAPHIQSELVAEWAHP
                     YSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISEYQ"
     gene            36966..37709
                     /locus_tag="RHX21_001253"
     CDS             36966..37709
                     /locus_tag="RHX21_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDV1986472.1"
                     /translation="MAIALVTGGSRGIGRATALLLAQEGYTVAVNYQQNLHAAQEVMN
                     LITQAGGKAFVLQADISDENQVVAMFTAIDQHDEPLAALVNNAGILFTQCTVENLTAE
                     RINRVLSTNVTGYFLCCREAVKRMALKNGGSGGAIVNVSSVASRLGSPGEYVDYAASK
                     GAIDTLTTGLSLEVAAQGIRVNCVRPGFIYTEMHASGGEPGRVDRVKSNIPMQRGGQA
                     EEVAQAIVWLLSDKASYVTGSFIDLAGGK"
     gene            complement(37766..39199)
                     /gene="bglA"
                     /locus_tag="RHX21_001254"
     CDS             complement(37766..39199)
                     /gene="bglA"
                     /locus_tag="RHX21_001254"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708664.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase BglA"
                     /protein_id="HDV1986473.1"
                     /translation="MKKLTLPKDFLWGGAVAAHQVEGGWNKGGKGPSICDVLTGGAHG
                     VPREITKEVLPGKYYPNHEAVDFYGHYKEDIKLFAEMGFKCFRTSIAWTRIFPKGDEA
                     QPNEEGLKFYDDMFDELLKYNIEPVITLSHFEMPLHLVQQYGSWTNRKVVDFFVRFAE
                     VVFERYKHKVKYWMTFNEINNQRNWRAPLFGYCCSGVVYTEHENPEETMYQVLHHQFV
                     ASALAVKAARRINPEMKVGCMLAMVPLYPYCCNPDDVMFAQESMRERYVFTDVQLRGY
                     YPSYVLNEWERRGFNIKMEDGDLDVLREGTCDYLGFSYYMTNAVKAEGGTGDAISGFE
                     GSVPNPYVKASDWGWQIDPVGLRYALCELYERYQRPLFIVENGFGAYDKVEEDGSIND
                     DYRIDYLRAHIEEMKKAVTYDGVDLMGYTPWGCIDCVSFTTGQYSKRYGFIYVNKHDD
                     GTGDMSRSRKKSFNWYKEVIASNGEKL"
     gene            39244..39555
                     /locus_tag="RHX21_001255"
     CDS             39244..39555
                     /locus_tag="RHX21_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HDV1986474.1"
                     /translation="MQPNDITFFQRFQDDILAGRKTITIRDESESHFKTGDVLRVGRF
                     EDDGYFCTIEVTATSTITLETLTEKHAEQENMTLPELKKVIADIYPGQTQFYVIEFKC
                     L"
     gene            39719..40378
                     /locus_tag="RHX21_001256"
     CDS             39719..40378
                     /locus_tag="RHX21_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HDV1986475.1"
                     /translation="MVQKPLIKQGYSLAEEIANSVSHGIGLVFGIVGLVLLLVQAVDL
                     NASATAITSYSLYGGSMILLFLASTLYHAIPHQRAKMWLKKFDHCAIYLLIAGTYTPF
                     LLVGLDSPLARGLMIVIWSLALLGILFKLTIAHRFKILSLVTYLAMGWLSLVVIYEMA
                     VKLAAGSVTLLAVGGVVYSLGVIFYVCKRIPYNHAIWHGFVLGGSVCHFLAIYLYIGQ
                     A"
     gene            complement(40455..41435)
                     /gene="ygfZ"
                     /locus_tag="RHX21_001257"
     CDS             complement(40455..41435)
                     /gene="ygfZ"
                     /locus_tag="RHX21_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-modifying protein YgfZ"
                     /protein_id="HDV1986476.1"
                     /translation="MAFTPFPPRQPTASARLPLTLMTLDDWALATITGADSEKYMQGQ
                     VTADVSQMAEDQHLLAAHCDAKGKMWSNLRLFRDGDGFAWIERRSVREPQLTELKKYA
                     VFSKVTIAPDDERVLLGVAGFQARAALANLFSELPSKEKQVVKEGATTLLWFEHPAER
                     FLIVTDEATANMLTDKLRGEAELNNSQQWLALNIEAGFPVIDAANSGQFIPQATNLQA
                     LGGISFKKGCYTGQEMVARAKFRGANKRALWLLAGSASRLPEAGEDLELKMGENWRRT
                     GTVLAAVKLEDGQVVVQVVMNNDMEPDSIFRVRDDANTLHIEPLPYSLEE"
     gene            41678..41944
                     /gene="sdhE"
                     /locus_tag="RHX21_001258"
     CDS             41678..41944
                     /gene="sdhE"
                     /locus_tag="RHX21_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD assembly factor SdhE"
                     /protein_id="HDV1986477.1"
                     /translation="MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDEKRIFI
                     RLLECDDPDLFNWLMNHGKPADAELEMMVRLIQTRNRERGPVAI"
     gene            41925..42332
                     /locus_tag="RHX21_001259"
     CDS             41925..42332
                     /locus_tag="RHX21_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YgfX"
                     /protein_id="HDV1986478.1"
                     /translation="MVLWQSDLRVSWRAQWLSLLIHGLVAAVILLMPWPLSYTPLWMV
                     LLSLVVFDCVRSQRRINARQGEIRLLMDGRLRWQGQEWCIVKAPWMIKSGMMLRLRSD
                     GGKRQHLWLAADSMDEAEWRDLRRILLQQETQR"
     gene            complement(42372..42893)
                     /gene="fldB"
                     /locus_tag="RHX21_001260"
     CDS             complement(42372..42893)
                     /gene="fldB"
                     /locus_tag="RHX21_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin FldB"
                     /protein_id="HDV1986479.1"
                     /translation="MNMGLFYGSSTCYTEMAAEKIRDIIGPELVTLHNLKDDSPKLME
                     QYDVLILGIPTWDFGEIQEDWEAVWDQLDDLNLEGKIVALYGLGDQLGYGEWFLDALG
                     MLHDKLSTKGVKFVGYWPTEGYEFTSPKPVIADGQLFVGLALDETNQYDLSDERIQSW
                     CEQILNEMAEHYA"
     gene            43005..43901
                     /gene="xerD"
                     /locus_tag="RHX21_001261"
     CDS             43005..43901
                     /gene="xerD"
                     /locus_tag="RHX21_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HDV1986480.1"
                     /translation="MKQDLARIEQFLDALWLEKNLAENTLNAYRRDLSMMVEWLHHRG
                     LTLATAQSDDLQALLAERLEGGYKATSSARLLSAVRRLFQYLYREKFREDDPSAHLAS
                     PKLPQRLPKDLSEAQVERLLQAPLIDQPLELRDKAMLEVLYATGLRVSELVGLTMSDI
                     SLRQGVVRVIGKGNKERLVPLGEEAVYWLETYLEHGRPWLLNGVSIDVLFPSQRAQQM
                     TRQTFWHRIKHYAVLAGIDSEKLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTT
                     QIYTHVATERLRQLHQQHHPRA"
     gene            43926..44636
                     /gene="dsbC"
                     /locus_tag="RHX21_001262"
     CDS             43926..44636
                     /gene="dsbC"
                     /locus_tag="RHX21_001262"
                     /EC_number="5.3.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional protein-disulfide
                     isomerase/oxidoreductase DsbC"
                     /protein_id="HDV1986481.1"
                     /translation="MKKGFMLFTLLAAFSGFAQADDAAIQQTLAKMGIKSSDIQPAPV
                     AGMKTVLTNSGVLYITDDGKHIIQGPMYDVSGTAPVNVTNKMLLKQLNALEKEMIVYK
                     APQEKHVITVFTDITCGYCHKLHEQMADYNALGITVRYLAFPRQGLDSDAEKEMKAIW
                     CAKDKNKAFDDVMAGKSVAPASCDVDIADHYALGVQLGVSGTPAVVLSNGTLVPGYQP
                     PKEMKEFLDEHQKMTSGK"
     gene            44642..46375
                     /gene="recJ"
                     /locus_tag="RHX21_001263"
     CDS             44642..46375
                     /gene="recJ"
                     /locus_tag="RHX21_001263"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HDV1986482.1"
                     /translation="MKQQIQLRRREVDETADLPAELPPLLRRLYASRGVRSAQELERS
                     VKGMLPWQQLSGVEKAVEILYNAFREGTRIIVVGDFDADGATSTALSVLAMRSLGCSN
                     IDYLVPNRFEDGYGLSPEVVDQAHARGAQLIVTVDNGISSHAGVEHARSLGIPVIVTD
                     HHLPGETLPAAEAIINPNLRDCNFPSKSLAGVGVAFYLMLALRTFLRDQGWFDERGIA
                     IPNLAELLDLVALGTVADVVPLDANNRILTWQGMSRIRAGKCRPGIKALLEVANRDAQ
                     KLAASDLGFALGPRLNAAGRLDDMSVGVALLLCDNIGEARVLANELDALNQTRKEIEQ
                     GMQVEALTLCEKLERSRDTLPGGLAMYHPEWHQGVVGILASRIKERFHRPVIAFAPAG
                     DGTLKGSGRSIQGLHMRDALERLDTLYPGMMLKFGGHAMAAGLSLEEDKFELFQQRFG
                     ELVTEWLDPSLLQGEVVSDGPLSPAEMTMEVAQLLRDAGPWGQMFPEPLFDGHFRLLQ
                     QRLVGERHLKVMVEPVGGGPLLDGIAFNVDTALWPDNGVREVQLAYKLDINEFRGNRS
                     LQIIIDNIWPI"
     gene            46466..47564
                     /gene="prfB"
                     /locus_tag="RHX21_001264"
     CDS             join(46466..46540,46542..47564)
                     /gene="prfB"
                     /locus_tag="RHX21_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311790.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HDV1986483.1"
                     /translation="MFEINPVNNRIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQP
                     DVWNEPERAQALGKERSSLEAVVDTLDQMKQGLEDVSGLLELAVEADDEETFNEAVAE
                     LDALEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYLRWAESRG
                     FKTEIIEESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFS
                     SAFVYPEVDDDIDIEINPADLRIDVYRASGAGGQHVNRTESAVRITHIPTGIVTQCQN
                     DRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMEDNKSDIGWGSQIRSYVLDDSRIK
                     DLRTGVETRNTQAVLDGSLDQFIEASLKAGL"
     gene            47574..49091
                     /gene="lysS"
                     /locus_tag="RHX21_001265"
     CDS             47574..49091
                     /gene="lysS"
                     /locus_tag="RHX21_001265"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HDV1986484.1"
                     /translation="MSEQHAQGADAVVDLNNELKTRREKLANLREQGIAFPNDFRRDH
                     TSDQLHAEFDGKENEELEALNIEVAVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARD
                     DLPEGVYNEQFKKWDLGDILGAKGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGL
                     QDQEARYRQRYLDLISNDESRNTFKVRSQILSGIRQFMVNRGFMEVETPMMQVIPGGA
                     AARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFT
                     MMELYMAYADYKDLIELTESLFRTLAQDILGKTEVTYGDVTLDFGKPFEKLTMREAIK
                     KYRPETDMADLDNFDSAKAIAESIGIHVEKSWGLGRIVTEIFEEVAEAHLIQPTFITE
                     YPAEVSPLARRNDINPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFLDQVAAKDAG
                     DDEAMFYDEDYVTALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMRPVK"
     gene            complement(49134..49682)
                     /gene="idi"
                     /locus_tag="RHX21_001266"
     CDS             complement(49134..49682)
                     /gene="idi"
                     /locus_tag="RHX21_001266"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HDV1986485.1"
                     /translation="MQTEHVILLNAQGVPTGTLEKYAAHTADTLLHLAFSSWLFNAKG
                     QLLVTRRALSKKAWPGVWTNSVCGHPQLGESSEDAVIRRCRYELGVEITPPESIYPDF
                     RYRATDPSGIVENEVCPVFAARTTSALQINDDEVMDYQWCDLADVLHGIDATPWAFSP
                     WMVMQATNREARIRLSAFTQLK"
     gene            49737..49808
                     /locus_tag="RHX21_001267"
     CDS             49737..49808
                     /locus_tag="RHX21_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986486.1"
                     /translation="MINQVSVYRQPPVLSGCRQVKTI"
     gene            complement(49805..49930)
                     /locus_tag="RHX21_001268"
     CDS             complement(49805..49930)
                     /locus_tag="RHX21_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986487.1"
                     /translation="MNFLMRAIFSLLLLFTLSIPVISDCVAMAIESRFKYMMLLF"
     gene            complement(49932..51380)
                     /gene="uacT"
                     /locus_tag="RHX21_001269"
     CDS             complement(49932..51380)
                     /gene="uacT"
                     /locus_tag="RHX21_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417364.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urate/proton symporter UacT"
                     /protein_id="HDV1986488.1"
                     /translation="MSAIDSQLPSSSGQDRPTDEVDRILSPGKLIILGLQHVLVMYAG
                     AVAVPLMIGDRLGLSKEAIAMLISSDLFCCGIVTLLQCIGIGRFMGIRLPVIMSVTFA
                     AVTPMIAIGMNPDIGLLGIFGATIAAGFITTLLAPLIGRLMPLFPPLVTGVVITSIGL
                     SIIQVGIDWAAGGKGNPQYGNPVYLGISFAVLIFILLITRYAKGFMSNVAVLLGIVFG
                     FLLSWMMNEVNLSGLHDASWFAIVTPMSFGMPIFDPVSILTMTAVLIIVFIESMGMFL
                     ALGEIVGRKLSSHDIIRGLRVDGVGTMIGGTFNSFPHTSFSQNVGLVSVTRVHSRWVC
                     ISSGIILILFGMVPKMAVLVASIPQFVLGGAGLVMFGMVLATGIRILSRCNYTTNRYN
                     LYIVAISLGVGMTPTLSHDFFSKLPAVLQPLLHSGIMLATLSAVVLNVFFNGYQHHAD
                     LVKESVSDKDLKVRTVRMWLLMRKLKKNEHGE"
     gene            51816..53735
                     /gene="ygfT"
                     /locus_tag="RHX21_001270"
     CDS             51816..53735
                     /gene="ygfT"
                     /locus_tag="RHX21_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417363.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent uric acid utilization protein
                     YgfT"
                     /protein_id="HDV1986489.1"
                     /translation="MNKFIAAEAAECIGCHACEIACAVAHNQENWPLSHSDFRPRIHV
                     VGKGQAANPVACHHCNNAPCVTACPVNALTFQSDSVQLDEQKCIGCKRCAIACPFGVV
                     EMVDTIAQKCDLCNQRSSGTQACIEVCPTQALRLMDDKGLQQIKVARQRKTAAGKASS
                     VAQPSRSAALLPVNSRKGADKISASERKTHFGEIYCGLDPLQATYESDRCVYCAEKAN
                     CNWHCPLHNAIPDYIRLVQEGKIIEAAELCHQTSSLPEICGRVCPQDRLCEGACTLKD
                     HSGAVSIGNLERYITDTALAMGWRPDVSKVVPRSEKVAVIGAGPAGLGCADILARAGV
                     QVDVFDRHPEIGGMLTFGIPPFKLDKTVLSQRREIFTAMGIDFHLNCEIGRDITFSDL
                     TSEYDAVFIGVGTYGMMRADLPHEDAPGVIQALPFLTAHTRQLMGLPESEEYPLTDVE
                     GKRVVVLGGGDTTMDCLRTSIRLNAASVTCAYRRDEVSMPGSRKEVVNACEEGVEFQF
                     NVQPQYIACDEDGRLTAVGLIRTAMGEPGPDGRRRPRPVAGSEFELPADVLIMAFGFQ
                     AHAMPWLQGSGIKLDKWGLIQTGDVGYLPTQTHLKKVFAGGDAVHGADLVVTAMAAGR
                     QAARDMLTLFDTKAS"
     gene            53735..54223
                     /locus_tag="RHX21_001271"
     CDS             53735..54223
                     /locus_tag="RHX21_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417362.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDV1986490.1"
                     /translation="MKSLIIVNPADCIGCRTCEVACVVAHPSEQELNADVFLPRLKVQ
                     RLDSISAPVMCHQCENAPCVGACPVGALTMGEQVVQTNSARCIGCQSCVSACPFGMIT
                     IQSLPGDTRQQIVKCDLCEQREEGPACVESCPTQALQLLTERELRRVRQQRIVASGEN
                     PL"
     gene            complement(54259..55626)
                     /gene="ghxQ"
                     /locus_tag="RHX21_001272"
                     /gene_synonym="ygfQ"
     CDS             complement(54259..55626)
                     /gene="ghxQ"
                     /locus_tag="RHX21_001272"
                     /gene_synonym="ygfQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine/hypoxanthine transporter GhxQ"
                     /protein_id="HDV1986491.1"
                     /translation="MSGDILQTPDAPKPQGALDNYFKITARGSTVRQEVLAGLTTFLA
                     MVYSVIVVPGMLGKAGFPPAAVFVATCLVAGFGSLLMGLWANLPMAIGCVISLTAFTA
                     FSLVLGQQISVPVALGAVFLMGVIFTAISVTGVRTWILRNLPMGIAHGTGIGIGLFLL
                     LIAANGVGMVIKNPIEGLPVALGAFTSFPVMMSLLGLAVIFGLEKCRVPGGILLVIIA
                     ISIIGLIFDPAVKYHGLVAMPSLTGEDGKSLIFSLDIMGALQPTVLPSVLALVMTAVF
                     DATGTIRAVAGQANLLDKDNQIINGGKALTSDSVSSIFSGLVGAAPAAVYIESAAGTA
                     AGGKTGLTATVVGALFLLILFLSPLSFLIPGYATAPALMYVGLLMLSNVSKLDFNDFI
                     DAMAGLVCAVFIVLTCNIVTGIMLGFVTLVVGRVFAREWQKLNIGTVIITAALVAFYA
                     GGWAI"
     gene            complement(55662..56978)
                     /gene="guaD"
                     /locus_tag="RHX21_001273"
     CDS             complement(55662..56978)
                     /gene="guaD"
                     /locus_tag="RHX21_001273"
                     /EC_number="3.5.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311783.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine deaminase"
                     /protein_id="HDV1986492.1"
                     /translation="MSGEHTLKAVRGSFIDVTRTVDNPEEIASALRFIEDGLLLIKQG
                     KVEWFGEWEDGKHQIPDTIRVRDYRGKLIVPGFVDTHIHYPQSEMVGAYGEQLLEWLN
                     KHTFPTERRYEDLEYAREMSAFFIKQLLRNGTTTALVFGTVHPQSVDALFEAASHINM
                     RMIAGKVMMDRNAPDYLLDTAESSYHQSKELIERWHKNGRLLYAITPRFAPTSSPEQM
                     AMAQRLKEEYPDTWVHTHLCENKDEIAWVKSLYPDHDGYLDVYHQYGLTGKNCVFAHC
                     VHLEEKEWDRLSETKSSIAFCPTSNLYLGSGLFNLKKAWQKKVKVGMGTDIGAGTTFN
                     MLQTLNEAYKVLQLQGYRLSAYEAFYLATLGGAKSLGLDDLIGNFLPGKEADFVVMEP
                     TATPLQQLRYDNSVSLVDKLFVMMTLGDDRSIYRTYVDGRLVYERN"
     gene            complement(56996..>57175)
                     /locus_tag="RHX21_001274"
     CDS             complement(56996..>57175)
                     /locus_tag="RHX21_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417358.2"
                     /note="high-affinity transporter for xanthine; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine permease XanP"
                     /protein_id="HDV1986493.1"
                     /translation="LGVSYDPEIFKILPASIYVLVENPICAGGLTAILLNIILPGGYR
                     QENVLPGITSAEEMD"
BASE COUNT        13867 a        14244 c        15344 g        13720 t
ORIGIN      
        1 ccgcacgagt attttatttt taccgccgga cggtacccta aaaataaaat aaggataatt
       61 tatgcggctt agtgattatt ttccagaatc atcaatctca gttatacatt cagcaaaaga
      121 ttggcaggaa gctatcgatt tctcgatggt atcattgctg gataaaaact atatcagcga
      181 gaattacatt caggcaatta aagattccac cattaacaat ggcccttatt atattctcgc
      241 accaggcgtg gcaatgcctc atgcgcgacc ggaatgtggg gcgcttaaaa ccgggatgtc
      301 tttgacatta cttgaacaag gtgtttattt tccggggaat gacgaaccaa ttaaattact
      361 catcggactc tctgctgccg atgccgattc gcacattggc gctattcagg cgttaagtga
      421 attactgtgc gaagaagaaa tactcgaaca actcttaaca gcatcatcag aaaaacaatt
      481 agcggacatt atcagccgcg gataattact ctctcctcta caggataata ttatggaaaa
      541 caagtctgct cgtgcaaagg tccaggcttt tgggggcttt ttgactgcaa tggtcatccc
      601 caatattggt gcttttattg cctggggttt tattactgcg ttatttattc ccaccggttg
      661 gctgcctaac gaacatttcg ccaaaattgt cggcccgatg attacctatt tattgcccgt
      721 gatgattggt tctacaggtg gtcatctggt cggcggtaaa cgcggggcgg tcatgggcgg
      781 aataggtact attggtgtga tcgttggcgc agagatcccg atgttccttg gctcaatgat
      841 catggggccg ctcggtgggt tggtcataaa atatgtcgat aaggcactgg aaaaacgcat
      901 acctgccggt tttgagatgg ttatcaataa cttctcatta ggtatcgcgg ggatgctcct
      961 ttgtctgctg ggttttgaag tgatcggccc ggcggtgtta attgccaata ctttcgtcaa
     1021 agagtgtatc gaggcgctgg tacatgcggg ttatctgcct ctgctgtcag tcatcaatga
     1081 accggcgaaa gtgcttttcc ttaataatgc gatcgatcag ggcgtctatt atccgctggg
     1141 aatgcaacag gcttcggtta acggtaaatc catcttcttt atggtggcct ctaacccagg
     1201 tccgggcctg gggctgctgc tggcgtttac cttgtttggt aaagggatga gtaaacgttc
     1261 tgcgcccggg gcgatgatta ttcacttcct cggtgggatc cacgaactgt atttcccata
     1321 tgtgctgatg aagccgctga ctattattgc catgattgcg ggcggtatgt ctggtacctg
     1381 gatgtttaac ttactggacg gtggtctggt ggctggccca agtccggggt ctatctttgc
     1441 ttacctggca ctgacgccga aaggctcgtt cctggcgaca attgccggtg ttacggtagg
     1501 taccctggtg tcctttgcta ttacttcgct gatactgaag atggaaaaaa cggtggaaac
     1561 ggagagcgaa gatgagtttg ctcagtcagc caatgcggtt aaggcgatga aacaagaggg
     1621 tgcattctcg ttaagcaggg ttaagcgtat cgcctttgtt tgcgatgcgg ggatgggctc
     1681 cagtgcgatg ggcgcgacca ccttccgtaa acgcctggaa aaagcggggc tggcaataga
     1741 agtaaaacat tacgcgatag aaaacgtgcc tgcggatgcc gatatcgtcg ttactcatgc
     1801 cagtctggaa gggcgcgtga aacgtgttac ggataaaccg ctgatattga ttaataacta
     1861 tattggcgat ccaaaactcg acactttatt taatcaatta accgccgaac ataaacactg
     1921 attacagagg taaaaatgaa aaccaaagtt gctgctattt atggcaagcg ggatgtccgt
     1981 ctgcgcgaat ttgaactgcc agaaattacc gataatgaat tactggtgag tgtaatttct
     2041 gacagcgtct gtttatccac ctggaaagct gcgttactcg gtagtgaaca taaacgcgta
     2101 cccgacgatt tagaaaatca tccggtcatt accgggcatg aatgtgccgg ggttattgtc
     2161 gaagtgggta aaaatctcac tggcaaatat aaaaaaggcc agcgttttgt attgcaacca
     2221 gcgatggggt taccaagcgg atattcagcg ggctacagct acgaatattt tggcggcaat
     2281 gccacttata tgattattcc cgaaatcgcc attaatttgg gctgcgtatt accgtatcac
     2341 ggctcttatt ttgctgcggc gtcgctggca gagcctatgt gctgcattat tggtgcttat
     2401 catgccaatt atcacaccac gcaatatgtt tatgagcatc gcatgggcgt caaacctggc
     2461 ggcaatattg cactgctggc gtgtgcaggt ccgatgggca ttggcgctat cgattacgcc
     2521 attaacggcg gcatacaacc gtcgcgggtg gtggtggtcg atatcgacga caaacgtctg
     2581 gcgcaggtgc agaagctgct gccggtggat ctggcggcca gtaaaggcat tgagctggtg
     2641 tatgtgaata ccaaagggat gagcgatccg gtccagacgc tgcgggcgct gacaggagat
     2701 gtcgggttcg atgacatttt tgtttatgcg gcggtgcctg ctgtcgttga gatggctgac
     2761 gaattactgg cggaagatgg ctgtctgaac ttctttgccg ggccgacgga taaaaacttc
     2821 aaagtgccgt ttaatttcta caacgtccat tacaacagca cgcacgtagt cggtacatcc
     2881 ggcggttcaa cggacgacat gaaagaggcg attgcgttaa gcgccacggg gcagttgcag
     2941 ccgtccttta tggtcacgca tatcggtggg ctggatgcgg tgccagatac cgtgctcaat
     3001 ctgccggata tccctggcgg taaaaaactc atttataacg gcgtgaccat gccgctcact
     3061 gccattgccg attttgccga aaaaggcaaa accgatccgc tgtttaaaga gttggcgcgg
     3121 ctggttgagg aaacgcacgg catctggaat gaacaggccg agaaatatct gctggcacaa
     3181 tttggcgttg atatcgggga ggccgcgcaa tgatgtccct ggcgtggcca ttatttcgcg
     3241 ttacggaaca ggcagcgttg gctgcctggc cgcaaaccgg atgtggcgac aaaaataaaa
     3301 ttgatggcct ggcggtcacc gcgatgcgcc aggcattaaa cgacgtcgct tttcgtggac
     3361 gagtggttat cggcgaagga gaaattgacc atgcgccgat gctgtggatt ggcgaagagg
     3421 tgggcaaagg cgatgggcca gaagtcgata tcgcggttga cccgattgaa ggcacgcgga
     3481 tggtagcgat ggggcagagc aatgcgctgg cggtcatggc tttcgcccct cgagatagcc
     3541 tgttacatgc gcccgatatg tatatgaaaa agctggttgt taatcgactg gctgccgggg
     3601 cgattgatct gtctttgcct ctggcggaca acttgcgtaa cgtggcgcgg gcgttaggta
     3661 aaccgctgga caagctgcgc atggttacgc tggataaacc gcgcctgagt gccgcgattg
     3721 aagaagcaac acagctgggc gtgaaggttt tcgctctgcc ggatggcgat gtcgccgcca
     3781 gcgtgctgac ctgctggcag gataatcctt acgacgtgat gtacaccatc ggcggtgcgc
     3841 cagaaggcgt gatttctgcc tgtgccgtta aagcattagg tggggatatg caggccgagc
     3901 tgattgactt ttgtcaggct aaaggggatt acacggaaaa tcggcagatt gcagagcagg
     3961 agcgcaagcg ttgtaaggca atgggcgttg acgttaaccg tgtgtactcg ctcgatgaac
     4021 tggtgagggg gaacgatatc ctctttagcg ctacgggcgt gacgggcggc gagttggtga
     4081 acggtatcca acagacggcg aatggggtgc ggacgcagac attactgatc ggcggcgcgg
     4141 accaaacgtg taatataata gactccctgc attgatggtg atctatcgga agaccaatgg
     4201 cgacgctgac agaagatgat gtgcttgagc aactggatgc acaggacaat ttattttcat
     4261 ttatgaaaac tgcgcattct attttgctcc aggggatacg ccagtttctg ccgtcgctgt
     4321 ttgtcgataa cgatgaagag atcgtcgaat atgcagtgaa gccgttactc gcccaaagcg
     4381 gcccgcttga cgatattgat gttgcgctgc gtttgattta tgcgctgggg aaaatggata
     4441 aatggctgta tgccgatatc acgcactttt cccagtactg gcattacctg aacgaacagg
     4501 atgaaacgcc cggatttgcc gatgacatga cctgggattt tatcagcaac gtcaatagca
     4561 taacctgcaa tgcgacgctc tatgatgcgt taaaagcgat gaagttcgcc gatttcgccg
     4621 tctggtcaga ggcgcgtttt agcggaatgg tcaaaacggc gctgacgctg gcagtaacga
     4681 ccaccttaaa ggaattaacg ccgtgaaaat tgaattaacg gtgaatgggc tgaacgtgca
     4741 agcgcagtac catgatgaag agatagaacg cgtgcataaa ccgctactgc gtatgctggc
     4801 ggccttacag gcggtaagtt cgcagcgacg tacggtggtt tttctttgcg ctccgccggg
     4861 gacgggtaaa tctaccttaa ctaccttctg ggaatatctc gcgcaacaag acccggaact
     4921 gcccgctatt cagacgctcc cgatggatgg ttttcaccat tacaatagct ggctggacgc
     4981 gcatcaattg cgccccttca aaggcgcacc agagacattt gacgttgtga aactggcgga
     5041 aaatctgcgc taggtcgtgg aaggagattg tacgtggccg cagtacgatc gacaaaagca
     5101 tgatcctgtt gaagatgcgt tgcacgttac cgcaccactc gtcatcgtcg aaggaaactg
     5161 gttgttgctg gacgacgaga agtggtgcca gcttgcgcaa ttttgtgatt tctcgatctt
     5221 tatcaacgcg ccagctactg cgttgcggga acgactggta gggcgcaagc tggcgggagg
     5281 ggtatcgctg gcagacgcag aagcttttta tgaccgtacc gacgggccga atgttcgccg
     5341 ggtgctggaa gagagtctgc ctgcaaattt gaccttaatg atgaccgcta cgggtgaata
     5401 tcgtctggtg gattaacgtt cctgattaga ccatcttcca gtcgcaccac acgagagaaa
     5461 tgacgccggg taaatgcggc gtcatgactg attgctacga cgctcgtgcc tcgctggccg
     5521 cacttctcca gccagctttc aaacacgctc aaccaatttt cgtcaaaatc ccgactcggc
     5581 tcgtccagca gcaatagtgg cggagagagt gcttccaggc aggcgacggc gaccatccgt
     5641 cgctgcgcac tatgcagatc caacgggtgc gagttggcag tgtctgctaa ctgacaacat
     5701 tgcagggcag catgggtacg ttgagtgatt tcatccgccg ggcatttttg cagtttcaaa
     5761 ccaaatgcga tctcgtcagc gacggtgctg tgaaaaagtt ggttttccgc ttcctgaaac
     5821 agtacgccaa cctttgccgc gcgctggcgg tttttcaggt ttttcatcgc ctgttgttgc
     5881 agcataaccg taccggctgt gggcgtaaga agacctgcca ttactcgtaa cagcgtcgat
     5941 tttcccgcgc cattgtcgcc ggtcagcgcc aaccattcac cttgtttgag ttgcagagaa
     6001 atgtcgcaaa gacaatccgt tgccgcgcca ggccagcgat aagatatctt atttaacgtt
     6061 aacatagtgg ctggagcgct ccgttttgca attgccacgc ttgctggcag tagttcagga
     6121 aaggtgtgcg atgacgttca aaaagaataa tcagcgaacc acgttcaaac gcccagtgtt
     6181 gtaagcgctg caacagcatt tcgctggcct gcggagtcag gcggctaaag gcttcatcaa
     6241 gaattaagag ctttggctgc atcgcgatgg cgcaggcgat gaccacgcgc tgtgtctctc
     6301 caccggagag tgttgccggg tgacgatggc gcaacggctg gcactcggtc agagtcaggg
     6361 cggcatcaat ccgcgccata atctctgctt cagcaagaca cagattttct ggcccaaagg
     6421 caacttcttc ttccacgcta aaggtacagc cggagagctg caaatagggc gattgctgga
     6481 cgagctggat ggtggcggat tgttcattaa gcgggagatg cccaatgggc gtaccgagga
     6541 gcgtccccgt gcctgttatc tctcctggca gaaagtccgg ataccagccc gccatcagct
     6601 gtgccagcgt acttttgcca ctgccgttgt caccaaagat ggcgaccatc cccggtttga
     6661 catagtgaaa gtcataacag aacggaggat gcgttgagtg tgtcgggcaa taacggaact
     6721 gttctaacgt aaccatatcc acgctccgaa ttctgtcagc atcagcaaga tcatggtgta
     6781 acgcgctacg cgttgtaggg tgctatcggc tggtgcccac aacgttgttc gtcggttgtg
     6841 gatccgaaat gcccgcatat ccagcgccgc accacggaca gccagatcgt taagcgcatt
     6901 gtgtgttagc ggaataatta acgcgggcat cgcacgtaaa cgctgatacc agccctcatc
     6961 cagcggcacg ccgcgggcac gctgcgcttc atgaataatc gctaattgcc gttttaactg
     7021 ctcaacgacc aataacggcc cggcaaacag ataagcgacg cctggcggca ggcgagaagc
     7081 aaacagagcg cgaataaaac attgcacggg gacgtactgc atccacaact gtgaggttga
     7141 aacaatcgcc agaatccgca accagagcgt aatagcatgc gaccaccgtt ctggcgagcg
     7201 tggcgtgccg cttagccatt ctggtagcca gccaccgtgt accagccaca gcccggctcc
     7261 cagcgagaac atcagccaga cgacatattt tgcccgccgc cgcgtggcct ttagcgcaat
     7321 aaggcagaaa aaggtcgccg cgctatagat tggcaaaatg gtctgcgcgg gcaggataag
     7381 cgtggtgcag gccgccaatg cccacagtgt taatgaggta aatggatgca tttagcgcac
     7441 ggcagccatt gccggaaaat ggcgcgtggt gcgaatcggc agctggcgca gtaaaagcca
     7501 gacaatcacc gctgtaagaa ttttatcgac caggttcgcg cctatcaccg taatcgccac
     7561 cgactccacc aggttttgcc ccatcgagtg catccaggca acgaacaaat cggctccgct
     7621 accggtgaca ccgccgaaca gcgcagtacg cagcggtaca gcgacgaccg ttaccgcaag
     7681 cgtaataatc acgccgctga caacgacttt tggcagggtg cgaaaccaac ccgctcgcgc
     7741 caggcaaccg gcgaccaggc cgatgaccat cgcgacgggt gcaaatgcgg cggcgatcgg
     7801 gttggtcagc aatccccaga gtaaattggt cagtaagccg gtcagcattc cgatcaccgg
     7861 accaagcagt accgcgctaa taagtgtgcc gatggagtcg agaaatatag gtaatttgac
     7921 catgctggcc agttgcccgc cgatcatatt gatggcgata gatataacga tcaacaccag
     7981 tgcctgactg gaaaagtggc tacgcgccat aagaaaacct ctttgaaagt agttatttaa
     8041 cgggggaaat atgcaactcg tcgtaaccag aaagcgcgca aggttggcgg ctaaacgcca
     8101 gttcctcaag gctaccgatc accagttcaa gcgtggtccg cacggtacag ccgggcatca
     8161 tatgaccgcc aagcatcgtg ccgtgtggat cggaaacgca gagatgaaga tgctcaccac
     8221 tctgttccag cgtgccgttt agtgagatca cttcgaatgt accgttcagg agcgtggtgc
     8281 cttcttgccc ggcatagcgc aaggcgacgt cagtcaggct accggtacag cctgcaatcc
     8341 aggcggcatg aagttgatgc tgctgtgcaa aagcgtgtag ctgggaaaaa acttcctgcc
     8401 cggggaggag gcgcagtgcg taaaagcgtg cggaggaaga atatgggtag ggcaatgtca
     8461 tcattggagt actccgaaac tcggacgtat tgcggataat atcgacgctg catcagtcat
     8521 attctgatat aagtcagggt ttgtgacggc acaacgaaaa gattttgcta cgcttattcg
     8581 tgattctgca aagtggaata aattccacag gggcggggct gaaaacgtga cgtaagtcag
     8641 ataattgctt tctttgactg gacaatcatt ccttttattc cacgtttcgc ttatcctagc
     8701 tgaagcgttt cagtcgatta aatgttcgac aattaaccaa tcagtcgcag tttgcgacag
     8761 gtaaggtttc cccggacgat ttgctggatt actctgtctg gcaaatttgc tcagggaaaa
     8821 ccttgcagga gatctatgac cgtacgcgta gcgataaatg gcttcggtcg catcgggcgt
     8881 aatgtggttc gtgctttgta tgaatccgga cgccgggcgg aaattaccgt ggtggcaatc
     8941 aacgaactgg cggatgctgc gggcatggcg catttgttga aatatgacac cagccatggc
     9001 cgttttgcat gggaagtacg acaggaacgc gatcaacttt ttgttggtga tgacgccatc
     9061 cgcgtattgc atgaacgttc actgcaatcg ctcccctggc gtgaacttgg cgttgatgta
     9121 gtcctcgact gcaccggcgt atatggctcc cgcgagcatg gcgaagcgca tattgccgcc
     9181 ggggccaaaa aagtgctctt ttcacatcct ggcagtaacg atctcgacgc gaccgttgtt
     9241 tacggcgtca atcaggatca acttcgtgcg gaacaccgca tcgtttctaa cgcttcctgt
     9301 accacgaatt gcataattcc cgtcatcaaa ttgttagatg atgcgtacgg tattgagtcc
     9361 ggcacagtga ccacaattca ctccgccatg cacgatcaac aggttattga tgcataccat
     9421 cctgacctgc gtcgcacccg ggcagccagc cagtcgatca ttccggtcga tactaaactg
     9481 gccgccggta tcacacgatt ttttccgcaa tttaacgatc gctttgaagc gattgcggta
     9541 cgtgtgccaa ccataaatgt gacggcaatc gatttaagcg tgacggtgaa gaaacctgta
     9601 aaagccaatg aagtcaacct gttgctgcaa aaagcagcac aaggtgcatt tcatggtata
     9661 gttgactata cggaattgcc gttggtctct gtagatttta accacgatcc gcacagtgcc
     9721 attgtcgatg gcacccaaac ccgggtcagt ggcgcacacc tgatcaaaac gttggtctgg
     9781 tgcgataacg aatggggctt tgctaaccga atgctcgaca cgacgttagc tatggctact
     9841 gttgctttca ggtaagacgc aagcagcgtc tgcaaaactt ttagaatcaa cgagaggatt
     9901 caccatgtct gtaattaaga tgaccgatct ggatcttgct gggaaacgtg tatttatccg
     9961 tgcggatctg aacgtaccag taaaagacgg gaaagtaacc agcgacgcgc gtatccgtgc
    10021 ttctctgccg accatcgaac tggccctgaa acaaggcgca aaagtgatgg taacttccca
    10081 cctgggtcgt cctaccgaag gcgagtacaa cgaagaattc tctctgctgc cggttgttaa
    10141 ctacctgaaa gacaaactgt ctaacccggt tcgtctggtt aaagattacc tcgacggcgt
    10201 tgacgttgct gaaggtgaac tggttgttct ggaaaacgtt cgcttcaaca aaggcgagaa
    10261 gaaagacgac gaaaccctgt ccaaaaaata cgctgcactg tgtgacgtgt tcgtaatgga
    10321 cgcattcggt actgctcacc gcgcgcaggc ttctactcac ggtatcggta aattcgctga
    10381 cgttgcgtgc gcaggcccgc tgctggcagc tgaactggac gcgctgggta aagcactgaa
    10441 agaacctgct cgcccgatgg tggctatcgt tggtggttct aaagtatcta ccaaactgac
    10501 cgttctggac tccctgtcta aaatcgctga ccagctgatt gttggtggtg gtatcgctaa
    10561 cacctttatc gcggcacaag gccacgatgt gggtaaatcc ctgtacgaag ctgacctggt
    10621 tgacgaagct aaacgtctgc tgaccacctg caacatcccg gttccgtctg atgttcgcgt
    10681 agcaaccgag ttctctgaaa ctgcaccggc taccctgaaa tctgttaacg atgtgaaagc
    10741 tgacgagcag atcctggata tcggtgatgc ttccgctcag gaactggctg aaatcctgaa
    10801 gaatgcgaaa accattctgt ggaacggtcc ggttggcgtg ttcgaattcc cgaacttccg
    10861 caaaggtact gaaatcgtgg ctaacgctat cgcagacagc gaagcgttct ccatcgctgg
    10921 cggcggcgac actctggcag caatcgacct gttcggcatt gctgacaaaa tctcctacat
    10981 ctccactggc ggcggcgcat tcctcgaatt cgtggaaggt aaagtactgc ctgcagtagc
    11041 gatgctcgaa gagcgcgcta agaagtaaaa aatcacaggg cagggaaacc tgcccttgtt
    11101 tcagcgcgct tttagagcac gcattttttc atactctaaa taattcgagt tgcaggaagg
    11161 cgacaagaga gtgaatcccc aggagcttac ataagtaagt gactggggtg agcgaacgca
    11221 gacgcagcac atgcaacttg aagtatgacg agtataaggc ccgacgatac aggacaagag
    11281 acatgtctaa gatttttgat ttcgtaaaac ctggcgtaat cactggtgat gacgtacaga
    11341 aagttttcca ggtagcaaaa gaaaacaact tcgcactgcc agcagtaaac tgcgtcggta
    11401 ctgactccat caacgccgta ctggaaaccg ctgctaaagt taaagcgccg gttatcgttc
    11461 agttctccaa cggtggtgct tcctttatcg ctggtaaagg cgtgaaatct gacgttccgc
    11521 agggtgctgc tatcctgggc gcgatctctg gtgcgcatca cgttcaccag atggctgaac
    11581 attatggtgt tccggttatc ctgcacaccg accactgcgc gaagaaactg ctgccgtgga
    11641 tcgacggtct gctggacgcg ggtgaaaaac acttcgctgc taccggcaag ccgctgttct
    11701 cttctcacat gatcgacctg tctgaagaat ctctgcaaga gaacatcgaa atctgctcta
    11761 aatacctgga gcgtatgtcc aaaatcggca tgactctgga aatcgaactg ggttgcaccg
    11821 gtggtgaaga agacggcgtg gacaacagcc acatggacgc ttctgcactg tacacccagc
    11881 cggaagacgt tgattacgca tacaccgagc tgagcaaaat cagcccgcgt ttcaccatcg
    11941 cagcgtcctt cggtaacgta cacggtgttt acaagccggg taacgtggtt ctgactccga
    12001 ccatcctgcg tgattctcag gaatatgttt ctaagaaaca caacctgccg cacaacagcc
    12061 tgaacttcgt attccacggt ggttccggtt ctactgctca ggaaatcaaa gactccgtaa
    12121 gctacggcgt agtgaaaatg aacatcgata ccgataccca atgggcaacc tgggaaggcg
    12181 ttctgaacta ctacaaagcg aacgaagctt atctgcaggg tcagctgggt aacccgaaag
    12241 gcgaagatca gccgaacaag aaatactacg atccgcgcgt atggctgcgt gccggtcaga
    12301 cttcgatgat cgctcgtctg gaaaaagcat tccaggaact gaacgcgatc gacgttctgt
    12361 aagatattcc tttctgctta tctcaaggcc cgctctgcgg gtcttttttt cgccaaaagc
    12421 aaaattgcct gatgcgctac gcttatcagg cctacacgta tcctgcaata tattgaattt
    12481 gcaggttttt gtaggccgga taaggcgttc acgccgcatc cggcatgaca aagcgcacat
    12541 tgatatctgt ctgagccccg ctctgcgggg attttttcgc caaaagcaag gtgattcaga
    12601 tgagaaatct gtgatctatt tggcaaaatt atgctttatt gtttaccctt gtcagactgc
    12661 ccgtcataag gcggcggagt gtatttctcc attttgagtc agttgaaaag gaatattgaa
    12721 tggaagattt gaatgttgtc gatagcataa acggcgcggg aagctggctg gtagctaacc
    12781 aggcgctgct gctaagttat gcagtaaaca tcgtggcggc actcgcgatc atcatcgttg
    12841 gtttgattat cgcgcggatg atttccaacg cggtgaatcg cctgatgatc tcccgtaaaa
    12901 tcgatgccac tgttgctgat tttctctctg cattagtccg ttacggtatt atcgccttta
    12961 cgctaatcgc tgcactggga cgcgtgggtg tacaaaccgc gtccgtcatt gctgtactcg
    13021 gtgccgcagg cttagctgtt ggtctggctt tgcaggggtc actgtctaac ctggccgctg
    13081 gcgtgttact tgtcatgttc cgcccgttcc gtgccggaga atatgttgac ctcggcggcg
    13141 tagccggtac tgtgctgagt gtgcagattt tctccaccac catgcgtact gcagacggta
    13201 aaattatcgt tattccgaac ggtaaaatta ttgccggaaa tattattaac ttctcccgcg
    13261 agccagttcg ccgtaacgaa tttattattg gcgtggcgta tgattccgat atcgatcagg
    13321 ttaagcagat cctgaccaat attatccagt ctgaagatcg cattttgaaa gatcgcgaaa
    13381 tgactgtgcg cctgaacgaa cttggtgcat cgtcgattaa tttcgtggtc cgcgtctgga
    13441 gcaacagcgg cgatctgcaa aacgtgtact gggatgtgct ggagcgtatt aaacgtgaat
    13501 ttgatgccgc cggtatcagc ttcccgtacc cgcaaatgga tgtgaacttt aagcgggtga
    13561 aagaagacaa agctgcgtaa tcaacgctga ggccagataa tactctctgg cctctctctt
    13621 attagttatt ctgattgcca attaatatta tcaatttccg ctaataacaa tcccgcgata
    13681 tagtctctgc atcagatact taattcggaa tatccaacgt gttttcttat tactttcaag
    13741 gtcttgctct tggggcagct atgattctgc cgctcggccc acaaaatgct tttgtgatga
    13801 atcagggcat tcgtcgtcag tatcacatta tgattgcctt actttgcgct atcagcgatt
    13861 tggtcctgat ttgcgcgggg atttttggtg gtagcgcgtt attgatgcag tcgccgtggt
    13921 tgctggcgct ggtcacctgg ggcggcgtag tcttcttgct gtggtatggt tttggcgctt
    13981 ttaaaacagc gatgagtagt aatattgagt tagctagtgc cgaagtcctg aagcaaggca
    14041 gatggaaaat tatcgccacc atgttggcag tgacctggct gaatccgcat gtttacctgg
    14101 atacttttgt tgtactgggc agccttggcg ggcagcttga cgtcgaacca aaacgttggt
    14161 ttgcgctcgg gacaattagc gcctctttcc tgtggttctt tgggctggct attctcgcag
    14221 cctggctggc accgcgcctg cgcacggcaa aatcacagcg cattatcaat ctggtagtgg
    14281 gatgtgtcat gtggtttata gccttgcagc tggcgagaga cggtattgct catgcacaag
    14341 ccttgttcag ttaggcgcta tctgatggaa aaataaaaca gaggcgctaa gcttgcctcc
    14401 agaggtcctg aattttgggc aagtcaatta acacggagag actaacgtga agttcaaagt
    14461 tatcgccctg gcggcattaa tgggtattag cgggatggca gcgcaggcta acgaattgcc
    14521 ggatggaccg catattgtca cctccggtac ggcaagtgtg gatgcggtgc cagacattgc
    14581 cactcttgcg attgaagtta acgtggccgc gaaggatgcc gctacagcca agaaacaggc
    14641 agatgagcgc gtcgcacaat acatttcctt ccttgaactc aatcagatcg cgaaaaaaga
    14701 tatcagctca gcgaatttac gcacccagcc agattatgat tatcaggatg gtaaaagtat
    14761 cctgaaaggc taccgcgctg tgagaacggt ggaagtcacg ctccgtcagt tagacaaact
    14821 gaattccttg ctggatggcg cgctgaaggc gggtcttaac gaaattcgtt ctgtgtcgct
    14881 gggcgtggcg cagccggatg cctataaaga caaagcgcgt aaggcagcga ttgataacgc
    14941 gattcatcag gcgcaggaac tggcgaacgg ctttcatcgt aaactggggc cggtatatag
    15001 cgtgcgctac catgtttcca actatcagcc cagcccaatg gtgcggatga tgaaagccga
    15061 tgccgcgccg gtgtctgccc aggaaactta cgagcaggcc gctattcagt ttgatgatca
    15121 ggtcgatgtg gtcttccagt tagaacctgt ggatcaacaa cccgctaaaa cacctgcagc
    15181 acaataatac ttgtagcccg acgtattcgt cgggctaatg cctttacccg atattgcctc
    15241 ctttttctgt aattttctgt aaaaccatga cgtaatcacc tatctttgct cgcggtttca
    15301 tcaaggatag gctgactgaa acggttaagc ggacaaggat gcggggaggg gggatggaca
    15361 tttttatttc gaaaaagatg cgcaatttca ttttattagc gcaaaccaat aatattgccc
    15421 gggcggcaga aaaaatccat atgacggctt cgccatttgg taaaagcatt gccgcgctgg
    15481 aagaacaaat tggctatacg ctatttaccc gcaaagataa taatatcagc ctcaataaag
    15541 ccggtcagga actgtatcaa aaactgttcc cggtttatca acgactttct gcgattgata
    15601 atgaaatcca taactcaggg cgtcgttcac gagaaattgt gattggcata gataatactt
    15661 atccgacaat tattttcgat cagttgatta gtctcggaga taagtatgaa ggcgtgaccg
    15721 cccagccagt tgagttcagc gaaaacggtg ttatcgataa tctttttgac cgtcagttag
    15781 attttattat ctccccacag catgtatctg cacgagttca ggaactggaa aacctgacta
    15841 tcagtgaatt accaccgctg cgattgggct ttctcgtttc tcgccgttat gaagagcgtc
    15901 aagagcaaga gctgcttcag gagctgccct ggctacaaat gcgctttcaa aaccgggcta
    15961 acttcgaagc aatgattgat gcgaatatgc gaccttgtgg gatcaatccc accattattt
    16021 atcgtcccta cagttttatg gccaaaatca gcgccgtgga gcgcggacat tttctgacgg
    16081 tgatcccgca ttttgcctgg cgactggtga atccggcaac gctgaaatat tttgatgcgc
    16141 cgcacaggcc gatgtatatg caggaatatc tttattcaat cagaaatcat cgttataccg
    16201 ccacgatgct tcagcatatt gctgaagatc gtgacgggac aaaccattaa cccagcatcg
    16261 agccggttgc aattaaatta cggtgtaagt cgaagacgtg gctaagatcg tggtgaatat
    16321 gtccgccggg cgcattttcc agatagcgat gcagataatc ccgatacata ggatgtgcac
    16381 aattatcaat gatagtgcgg gcgcgttgaa gcggggaaag accgcgcaga tcggcgatcc
    16441 cttgttcggt gatgatcact ttgacgctgt gttcgctgtg atcaacatgg ctgcacattg
    16501 gcacgacggt tgagatcttg ccttctttag caatcgacgg agccataaag atcgacagat
    16561 acgcgttgcg ttcaaaatca ccgctgccgc cgatgccgtt catcagatcg accccggcta
    16621 cgtgcgttga gttggcatgc ccgtaaatat caaactccag gccgacgttc agagcgatga
    16681 cgcccagacg acggatgatt tccgggttat tggaaatctc ctgcggacgc aacacaatgc
    16741 ggctggcaaa gtaatccata ttgtcgtaaa tcttgcgcag ggaatcggcc gagattgtca
    16801 ggctggaggc gctggccccg ctgattttgc cggtttccag taaatgcacc accgattcct
    16861 gtagcacttc cgaatacatc atgaacggag gaatttccgg gttttccccc agacgcgcca
    16921 ttaccgcatt attgatattg cccacgccac tttgcagcgg cagaaattcc ggcggaatac
    16981 gcccatgcgc catttcctgc aataagaacg tgaccacgtt atcggcaatc tgctggcaca
    17041 tgggattttg cttatccagc atattaccgg cgtcgggcaa gttggtttcc acgacggcga
    17101 caatcttttt cggatcgatt tgcacatagc gggtaccgac gcgatccatt gcatggaaga
    17161 tcgacacgct attgcgccgc ggtggcgcgc caggaatcac aatatctgcc agttctgcaa
    17221 cgcgcggatc gtgatagtga ttaagttcaa tgatcacttt cttcgctcgc agcagccagg
    17281 tcggcgcatt accgatcccg ctggttaacc agactcgacc atccggtgcc agtgccgatg
    17341 cttcaatgac ggcaacatca atgtcgccga agaaaccgta attgaccatt tgcgccactt
    17401 cgctcaaatg caggtcaacg aaactcaccg cgccctgatt gatcttttta cgtaaaccgg
    17461 acgatgtttg atatggcgca cgccaggaaa cagcatcggc gtcagaaagt acatcgtcag
    17521 cggcggcgct gattgacgcc cccgtcagca ggcgaatttg atacggcttt ttggcctcat
    17581 gctgttcgtt agctctgcgg gcaatcgcgg tgggtagggc tttcggcgaa cccgccgggg
    17641 taaagccgct aaatgccacc atgtcgttat gctggataat ttctgccgct tcatcggcgg
    17701 tcatccttgt ccactgagtt tccattttta ctccttcgtt cgcagggatt aatgaccaac
    17761 gaaattaggt ttacgttttt cgaggaaagc gttcattcct tcctggtaat cttcgctgtc
    17821 ataaaccgcg cgtcgcatcc cctgaatacg ttcaaattca tcggagttca tggtgtgcgc
    17881 ttcgcccagt acacgcagct cttctttgat aacagcaatg gctaacggcg ctttctcaga
    17941 gatgtggtgc gccatttgta aggtgaaatc ttccagttct tccacttcca caacatggtt
    18001 gaggatgccg acagccaacg cgcgctgggc ggtgattggc gaagcggtaa aaatcagttc
    18061 tttgacaatg tggaagcccg cgtcgcgggt caggttgtga atgccgacca ggttatacgg
    18121 gacgccgagg tttacaggcg tcattgagaa ggttgaggta ctggcggcga taatcagatc
    18181 ggaactcatg atcatttcaa atgcgccacc ccaaacacta ccttccacca tcgaaatgat
    18241 cggtttcggg aatttttgga tcatgcgggt gatttgacgc aatggatcat cataggagag
    18301 cggatcgcga ccgccagacg gcagttcgtg aatatcgtgg cctgcggaga agactttgga
    18361 tccactcggc gcgcgcaaaa tgatacagcg aatttccggc cggttgagat cgcttaatgc
    18421 ctgcataaga tcatcaataa agactttact taaggcatta agtttgcggc catagttaaa
    18481 ctcaatgacc gccactttgt tgatagtgac aacgttaaca tactgataag acataaaaat
    18541 tcctttaatc aaaatattgc gtctggataa attcactgag ctgccgcagg ccggtgcgcg
    18601 gtgagagcgt attgtttttg accgctaaaa gcgtctggcg gtaatagcga tcgaaatctt
    18661 cattcgcgaa caggtgatgc agtacttctt cttcggtctg cttacgcagc cattccaccg
    18721 attgttgttg ccgcacttgt tgtaaacgac cactggcagt tagcgcggtt ttgaagtcga
    18781 tgatggcgtg ccagatctca tcgattccac gtttttccag tgcgctacaa gtcagaaccc
    18841 gtggctgcca ttcgtcgtat ttacgtcgca gaatatgcag ggcactctcg tacatatgcc
    18901 gggcaatggc gacattggta tggttatcgc catcgtcttt gttgataacg agcagatcag
    18961 ccacttccat cagccctttt ttaatgccct gcagatcatc gccgccaccg gcaatttgca
    19021 acgagataaa acagtccacc atgcgggcga cttccgtttc cgactgcccg acgccaaccg
    19081 tttcgacaat cactacgtca taacccgccg cttcgcataa cagcattaat tcccgcgctc
    19141 gctgactggc accgcccaga tgaccggagg atggtaccgg gcgaataaac gccgcttcgg
    19201 cacgcgccag gtcattcatg cgggttttat ccccgagaat gctaccgcca gtgaccgggc
    19261 tgctgggatc gaccgcaata accgcgacct ttaatccctc acgaatcaac aacatgccaa
    19321 aggcttcaag aaaggtactt ttccccgcgc cgggtgtgcc ggtaacgccc agtcgcaggg
    19381 cgttaccgca gtacggcata atggcatcaa gcagttgcgt acttagcgcc tgatgactcg
    19441 ggtgacggct ttccaccagc gtcatggcct gggcgagtgt ggcacgctca ccctgacgta
    19501 agcggcgaat actttctgcc agcgtggctt cattaatcat gatgctggct tatcagattc
    19561 agtacgtcgc gcacactctc gagcataggt gtacctggac cataaatcgc cgccacgccg
    19621 cgctcttgca ggaaggcgta atcctgcggt ggaatgacgc caccggcgac tacgcagata
    19681 tcttcgcgtc cccatttttt cagcgcttcg accagttccg ggatcagcgt tttatgaccg
    19741 gcagccagtg aggatgcgcc cactacgtga acgtcgtttt ctacggccag gcgggcgatc
    19801 tcttcaggtg tagagaacat cgggcttaaa tctacgtcga aaccgagatc ggaataggcg
    19861 ctggcgatca ctttcgcgcc gcgatcgtgt ccatcctggc ccatcttagc gatcagaatg
    19921 cgcgggcgac gaccattgtc ggcaaggaac tgctccgttt gcgcaacaat ggcatcgaac
    19981 tcggaggccg atttctcaga ctgatgatag ctttgcgcaa tcacgccggt aacacactgg
    20041 cttggcacca gataacggtc gaaagcgact tccagcgcat cggaaatttc acccagggtg
    20101 gcgcgaacgc gagcggcatt aacagcggca gccagcaggt tttcgttatg ctgtgcggcg
    20161 tgagtcaggg cgttcaacgc ggcggttacg gcggcatcat cacgggtggc gcgaatgcgt
    20221 tccagcgaag caatttgctc gttacgcacc atcacgttgt cgatctcaag tacatcggtt
    20281 tcgtcttcgt gatccagttt gtacttgttg acaccaacga tgacacgctt gccctggtcg
    20341 atcagcgact gttcgcgcgc tgaggcctct tcgatcattc gttttggcag acctgcttcg
    20401 atcgctttcg ccatgccacc ggcttcgtcg atctgttgga taatagctct ggcttgtttg
    20461 acgatttgat cggtcagcga ctcaatgtaa taggatccgg ccagtggatc gacggtgcgg
    20521 cagagttctg attcttcctg gatgatgatc tgggtgttgc gggcaatgcg tgctgagaaa
    20581 tcggtaggca aaccaagcgc ttcgtcaaag gcgttggtat gcagtgactg agtaccgccc
    20641 agcgtcgcag ccagcgcttc aatggtggtg cggataacgt tgttatacgg atcctgttca
    20701 gtcaggctcc agcctgaggt ctggcagtgg gtacgcagcg ccagtgattt cggatcctgt
    20761 gcgccaaatc cactgaccgc ttcgctccat aaataacgtg ccgcacgcaa catggcgacg
    20821 ttcataaaca gatccatgcc gataccgaag aagaacgaca ggcgaggagc gaagtcatca
    20881 attttcagtc cggcagagat tgctgctttg atgtactcaa tcccatcagc gagcgtaaat
    20941 gctacctgct gcacgcagtt ggcacccgct tcacccatgt ggtaaccgct gatactgatg
    21001 gtattaaatc gcggcatgtt gccggaacac caggcgatga tgtcggcgat aatgcgcatt
    21061 gacggttttg gcgggtaaat ataggtgttg cggcagaggt actctttgag gatatcgttc
    21121 tgaatggtgc cggtcagttt atcaggtgta acaccttgct cttctgcggc gacgatataa
    21181 aacgccagta ctggtagcac tgcgccattc atggtcatcg aaaccgacat tttatccagc
    21241 gggatctggt cgaacaggac tttcatatct tccacggtgt cgatagcgac gcccgctttg
    21301 ccgacgtcac ccgccacgcg tgggttatcg gagtcgtagc cacggtgggt ggcaaggtca
    21361 aacgcaacgg aaagaccttt ttgcccggcg gccaggttac ggcgataaaa agcgttggac
    21421 tcttttgctg ttgaaaaacc agcatactga cggatggtcc acggttgggc ggtatacata
    21481 gtggcacgcg ggccacgaac gtagggcggc aaaccaggaa gggtacctgt cacctccaga
    21541 ttatcgagat cggcttcggt atacagcggc ttgatggcga tcccttccgc ggtttgctga
    21601 accagcgagt cgacagtttt ctcccgacgg ctcaattcct tgttggcaag ctgttgccac
    21661 tcctgctcgt tagacattat ttgctccgta aaacgcaatc aaaatgaggg tatttgcgct
    21721 tacggtgagc tttttacgtg ggtttgtcgc cagcaaaaaa aatgcattca gacgtcgttt
    21781 tttgccgcct gagatttgtc tattttgtga tgtgattcaa ggaatacaaa aagaagtgag
    21841 gataacgcct gatatgtgct atcaggcatt atttgatgga ttaatcctga cgaaggactt
    21901 tgtgaccata atcgagcaac gcatcagtga ctttacgcat catgcggctt tcaggagcaa
    21961 agcggtgcca gtagagcatc cggcgttgaa atagccccgg cgttaagtca atcagttcac
    22021 cgctggccag ttctttctcg atttgcaggt gcgggatcat acagcaggtg gtgccctggc
    22081 gagcaagttg tacgaacgct tctgaagaat taacgatatg gcagggcacg ctgcctggag
    22141 gcagatcgaa gttttgctgc aaaaaggcct ggtgcatatc gtcaagatgg tcaaacgcga
    22201 ccactggcgc tttcagtaat gccgaacgcg ttacgccgtt agggaaatat ttttcggcaa
    22261 agggttttga gctgacgaac agatagtcga gcgcaccaag tttatcgaca agacagctcg
    22321 gcagcgcctg atgttgaata ctcaccgcgc cgaccacttc gccgcggcgc agacgttcct
    22381 gagtgcgggt ttcatcttct acctgcaagt tgaggcggat aggcgaatca gccaacacag
    22441 gagccagtgc aggaagcaac cacgtcgcca gactgtcggc gttgaccgcc agtgaaagca
    22501 gcagcggagt cgaaccggtt tgttcatcgc ccagccactc ttcttccagc aactccacct
    22561 ggcgcagcag tgccagcagt ttttgccctt gttccgtcgg gcgcggcggt acggtacgca
    22621 ccaacagcgg ctgcccgaac atattttcca gttgcttaat gcgctgtgag acggctgatt
    22681 gtgtaatgca cagcttttgt gccgcgcgct caaatcctcg ttcacgtatc accgcatcca
    22741 gtgcctgtaa tgttctgtag tccgggcgtt tcattgctgt tgtctgctcc tggtaaatgc
    22801 tttttcctgc actatgacac aattttgtgt caggttgcat ataccgaagc cgtcggcggg
    22861 taacatttgt attcgtggtt aaacgcgcag cttaaaagat cagggatttg cgctaatgca
    22921 tttcgctcag cgagttcgcg ccctggttgt gttgaatggc gtggcgttat tgcctctgtt
    22981 cgcaccgtgg agcggcatac ccagaccgtt gtatgcttta tttgcggggc gaaaggggat
    23041 gcccgccatt gcgcgatatt ttatggatga gttaaccacg cggcttgcca acggggtctg
    23101 aatcgctttt tttgtatata atgcgtgtga aatttcatac cacaggcgaa acgatcatga
    23161 cgcaggatga attgaaaaaa gcagtaggat gggcggcact tcagtatgtt cagcccggca
    23221 ccattgttgg tgtaggtaca ggttccaccg ccgcacactt tattgacgcg ctcggtacaa
    23281 tgaaaggcca gattgaaggg gccgtttcca gttcagatgc ttccactgaa aaactgaaaa
    23341 gcctcggcat tcacgttttt gatctcaacg aagtcgacag ccttggcatc tacgttgatg
    23401 gcgcagatga aatcaacggc cacatgcaaa tgatcaaagg cggcggcgcg gcgctgaccc
    23461 gtgaaaaaat cattgcttcg gttgcagaaa aatttatctg tattgcagac gcttccaagc
    23521 aggttgatat tctgggtaaa ttcccgctgc cagtagaagt tatcccgatg gcacgtagtg
    23581 cagtggcgcg tcaactggtg aaactgggcg gtcgtccgga ataccgtcag ggcgtggtga
    23641 ccgataatgg caacgtgatc ctcgacgtcc acggcatgga aatccttgac ccgatagcga
    23701 tggaaaacgc cataaatgcg attcctggcg tggtgactgt tggcttgttt gctaaccgtg
    23761 gcgcggacgt tgcgctgatt ggcacacctg acggtgtcaa aaccattgtg aaatgatctg
    23821 acgggggaac ctcccccgtt aaaaaaattc tcttcattaa atttggtgac atgtgtcacg
    23881 cttttaccag gcaattgtcg attgctctaa ataaatcctc taaaccagca tattcatcca
    23941 agaattacct ttgcgtgata tttcctcaac atcgcgacgc aaacgttcat attgccgcaa
    24001 tattattttt tgatatgttg aaaggcggat gcaaatccgc acacaacatt tcaaaagaca
    24061 ggattgggta aatggcaaag gtatcgctgg agaaagacaa gattaagttt ctgctggtag
    24121 aaggcgtgca ccaaaaggcg ctggaaagcc ttcgtgcagc tggttacacc aacatcgaat
    24181 ttcacaaagg cgcgctggat gatgaacaat taaaagaatc catccgcgat gcccacttca
    24241 tcggcctgcg atcccgtacc catctgactg aagacgtgat caacgccgca gaaaaactgg
    24301 tcgctattgg ctgtttctgt atcggaacaa accaggttga tctggatgcg gcggcaaagc
    24361 gcgggatccc ggtatttaac gcaccgttct caaatacgcg ctctgttgcg gagctggtga
    24421 ttggcgaact gctgctgcta ttgcgcggcg tgccggaagc caatgctaaa gcgcaccgtg
    24481 gcgtgtggaa caaactggcg gcgggttctt ttgaagcgcg cggcaaaaag ctgggtatca
    24541 tcggctacgg tcatattggt acgcaattgg gcattctggc tgaatcgctg ggaatgtatg
    24601 tttactttta tgatattgaa aacaaactgc cgctgggcaa cgccactcag gtacagcatc
    24661 tttctgacct gctgaatatg agcgatgtgg tgagtctgca tgtaccagag aatccgtcca
    24721 ccaaaaatat gatgggcgcg aaagagattt cgctaatgaa gcccggctcg ctgctgatta
    24781 atgcctcgcg cggtactgtg gtggatattc cggcgctgtg tgatgcgctg gcgagcaaac
    24841 atctggcggg ggcggcaatc gacgtattcc cgacggaacc ggcgaccaat agcgatccat
    24901 ttacctctcc actgtgtgaa ttcgacaacg tccttctgac gccacacatt ggcggttcga
    24961 ctcaggaagc gcaggagaat atcggcctgg aagttgcggg taaattgatc aagtattctg
    25021 acaatggctc aacgctctct gcggtgaact tcccggaagt ctcgctgcca ctgcatggtg
    25081 gtcgtcgtct gatgcacatc cacgaaaacc gtccgggcgt gctaactgcg ctgaacaaaa
    25141 tcttcgccga gcagggcgtc aacatcgccg cgcaatatct acaaacttcc gcccagatgg
    25201 gttatgtagt tattgatatt gaagctgacg aagacgttgc cgaaaaagcg ctgcaggcaa
    25261 tgaaagctat tccgggtacc attcgcgccc gtctgctgta ctaattcccc ttctctgaaa
    25321 attaacgggc aggtcactga cttgcccgtt tttttatccc ttctccacac cgttgccgcg
    25381 ttgcgcattc tactttgcga gtctgctcca gaaaataaat caaagtcaga tcaatgcgtt
    25441 gtgtttattt aatggggatt tacgatggcg ggacagcatg gggctgtaac ggtaaagccc
    25501 tcaccgaagc gagggcttaa aggagaaggg ttatgatgcg acttgtcatc atactgattg
    25561 tactgttact gataagtttc ggagcttatt aacagtcagt ctcaggggag gagtcatcct
    25621 cccttaccct tactcactaa attaggtcaa agaatcaacg atgtcaatca gggcgatgcg
    25681 gggtgcatcg ccctgaaccg aactttttga tagccacttc atcgcccacg tttactgccg
    25741 taatagatcc tttttcccaa aaattatctc tgttttgcat ggggtttttc gagcacgctc
    25801 gaagaaaaga tttaaaggta gatcaatgcg ttgtggttat ttaaagagag cttacgatag
    25861 ctgggcagca tggggctgta acggtaaagc cctcaccgaa gcgagggctt gaaggagaag
    25921 ggttatgatg cgacttgcca tcatactgat tgtactgtta ctcataagtt tcccagctta
    25981 ttaacagtca gtcacagggg aggagcaatc ctcccttacc cttactcact aaattaggtt
    26041 aaagaatcaa cgatgtcaat cagggcgatg caggtgtatc gcccttacca ctcccagact
    26101 ttcgacggtg taaccaccgc aggaagaggg atatcccact cttcaacggg gagtttttcc
    26161 accaactgac aatcatgcgc ataacccacc ggttgcgttt tatagtgctg ccagttttgt
    26221 aaggtccgat cataaaaacc accgcccatt cccaggcgct gaccgtactc atcaaaggcg
    26281 accagcggtg tgatcagcac gtctaatcgg gaaaggggta gcacgtcacg cacatccagt
    26341 tttggctcat ggatcttcaa cctgttcatc accagttcgc tttgcggatg gtaattcagg
    26401 aacagcaaat taccggcact aaagggatgc aaaactggaa gatatacgcg cttaccggcg
    26461 cgccagagtt gttctattag cggctgggtg tcgagttcac catcaaaaga gaggaataca
    26521 gcgaccgtat gcgccatcac caccggggga taagtcatca tccgggtagc ggcttgttga
    26581 cccatttcct gctgttgttc cggcgttaac gcacgacgac gttgccgaat cattttgcgg
    26641 atttcttgtc gggataatgt cagtgggagt tctggtagtt gcgtcatggc tggtgccaga
    26701 taagaaggga atctccgaga tgccgccgca ggctgtaacc cttgaaccct tggttcaagg
    26761 tgaatgtgtc gtcgcagttt taaggcttct cggacggacc gagcatgctc accaaccgcg
    26821 gagcgccaca ttcttgtggt atgaaatatc ggctcagggg actggcccgc ttgcgaacat
    26881 ctcagagaaa ttttgtcttc acggttactc taccacagta aaccgaaaag tgtcattcaa
    26941 agttttggtt agttttttcg gtgatgcgac cttgttcaag taacgcttgt tctatggtct
    27001 gctgcagcat ccgaatacgc tgttccatac ttgccgcgta gtcacgagtc ttcgcttttt
    27061 cttgcgctaa ctcatagctg atattcaatg cggcaatgaa gaccaactgt tcagtatttg
    27121 tgactctagt gcgttctttc agatcttgca accgttggtt cagatcgtcc gctgcctgat
    27181 tcaacgcatc cctttggtca ggcgggcagt tcacacgcag tgaacggcca aaaatttgga
    27241 tatcgacggg ttgtgcagac atgccacctt cctgctgatt gactgcgctg ccttcgtctt
    27301 tagacccatg gtctgcgaag gggcgacact atagctaccc tgatgagaag agacaagccc
    27361 ttttctggtc caccagggcc caaagtggta gcatatcatg aatattcctc cctttgacga
    27421 cgaatgctta tgtctataca gaacgaaatg cctggttaca acgaaatgaa ccagtatctg
    27481 aaccaacaag ggacgggtct gacccctgct gagatgcatg gtttaatcag tgggatgata
    27541 tgtggcggta acgatgacag ctcatggcta ccgctacttc acgacctgac gaacgaaggc
    27601 atggctttcg gtcatgagct ggcacaggca ctgcgtaaaa tgcactctgg caccagcgat
    27661 gccctgcagg atgacggctt cctttttcag ctttatctgc ctgatggcga tgatgtcagc
    27721 gttttcgatc gggctgatgc attggcaggt tgggtcaatc acttcctgct tggtcttggc
    27781 gttacgcaac cgaagctgga taaagtgacc ggcgaaaccg gtgaagctat cgacgatctg
    27841 cgtaacattg cgcaactggg ttacgacgaa gacgaagatc aggaagagct tgaaatgtcg
    27901 cttgaagaga tcatcgaata cgttcgtgtt gccgcgctgt tatgccacga cacctttact
    27961 catccgcaac cgaccgcgcc agaagtacaa aaaccgactc tacactaaaa acaaaaaacg
    28021 taaggagagt gttatgagtg agatatcccg gcaagagttt cagcgtcgcc gtcaggccct
    28081 ggtggagcaa atgcaacccg gcagcgccgc gctgattttt gctgcaccag aagtaacacg
    28141 tagcgccgac agcgaatacc cctatcgtca gaacagtgac ttctggtact tcaccggctt
    28201 taacgaaccg gaagcggtgc tggtgctgat taaaagcgat gacactcata accacagcgt
    28261 tctgtttaac cgcgttcgcg acctgacggc ggagatctgg tttggccgtc gcttaggcca
    28321 ggatgccgcg ccagagaaac tgggcgttga ccgcgcactg gcattcagcg aaatcaatca
    28381 gcaactttat caactactta acggcctgga tgtggtttac catgcccagg gcgaatatgc
    28441 atatgctgat gaaatcgtga acagtgcgct ggaaaaactg cgtaaaggtt cgcggcaaaa
    28501 tctcaccgca ccggcaacga tgatcgactg gcgtcctgtt gttcatgaaa tgcgcctgtt
    28561 caaatcgcca gaagagattg ccgtactccg ccgcgcggga gaaatcaccg ccctggcaca
    28621 tacccgggcg atggaaaaat gccgtccggg aatgttcgag taccatctgg aaggcgaaat
    28681 tcaccacgaa tttaaccgcc acggtgcgcg ctatccttcc tataacacca ttgtcggcag
    28741 cggtgaaaac ggctgcattt tgcactacac cgaaaacgag tgtgaactgc gtgacggtga
    28801 cctggtgttg attgacgcgg gttgtgaata caaaggttac gctggcgata ttacccgcac
    28861 cttcccggtc aacggcaaat tcactcaggc ccagcgtgaa atctacgaca ttgtgctgga
    28921 gtctctcgaa accagcttgc gcctgtatcg tccgggaact tccatgcagg aagtcaccgg
    28981 tgaagtggtg cgcatcatgg ttagcggcct ggtaaaactc ggcattctga aaggtgatgt
    29041 tgatgaactg atcgctcaga acgcccatcg tcctttcttt atgcatggcc ttagccactg
    29101 gttagggcta gatgtccatg acgttggcgt ttatggtcag gatcgctcgc gcattctgga
    29161 accggggatg gtactgaccg tagagcctgg tctgtatatc gcgccggatg cggatgtgcc
    29221 agaacaatat cgcggtatcg gcattcgtat tgaagacgac attgtgatta ccgaaaccgg
    29281 caacgaaaac ctcaccgcca gcgtggtgaa aaagccggaa gaaatcgaag cgttgatggc
    29341 agctgcgaga aagcaatgag cgtaatcatc gtcggtggcg gcatggcggg cgcgacgctg
    29401 gcgctggcta tttcccggtt aagtcacggg gcgttgccgg tacatttgat tgaagcgact
    29461 gcgccagagt cacatgctca tccgggcttt gatggacgag cgatagcgct ggcggcgggt
    29521 acctgtcagc aactggcgcg catcggcgtt tggcaatctc tggcggattg cgcaactgcc
    29581 atcaccaccg tgcatgtcag cgatcgtggt cacgctggat ttgtcaccct cgccgcagaa
    29641 gattaccaac tggcggcgct gggacaggtt gtcgaattgc acaatgtcgg gcaacggctg
    29701 tttgcattgc tgcgtaaagc acctggcgta acgctgcatt gccctgatcg cgtggctaac
    29761 gttgcccgta ctcagagtca cgttgaagtg acgctggaga gtggcgagac gctgacgggc
    29821 cgcgtgctgg tagccgctga tggcacccat tcagcgttag ccaccgcgtg cggcgttgac
    29881 tggcagcagg agccttacga acaactggca gtgattgcca acgttgctac ttctgttgcg
    29941 cacgaaggcc gcgcttttga acgcttcacg caacatggcc cgctggcgat gttgccgatg
    30001 tctgacggac gctgttcgct ggtctggtgt catccactgg aacggcgcga agagctgctg
    30061 tcgtggagtg acgagaagtt ttgccgtgaa ctccagtcgg cctttggctg gcgacttgga
    30121 aaaattaccc acgccggtaa acgcagtgct tatccgctgg cgttaacccg cgccgccaga
    30181 gctattaccc atcgtaccgt gctggtgggc aatgcggcgc aaactctgca cccgattgcc
    30241 gggcaagggt ttaacctcgg tatgcgagat gtcatgagcc ttgcggaaac cctgactcag
    30301 gcgcatgagc gcggagaaga catcggtgat tacggcatat tgtgccgcta tcagcagcgt
    30361 cgacagagcg atcgcgaagc aaccattggc gtcacggaca gccttgtaca tctttttgcc
    30421 aaccgttggg caccgctggt tgtcgggcgc aacatcggac tgatgacgat ggaattattc
    30481 accccggcac gcgatgtgct ggcgcagcgc accctcggtt gggtggcgcg ttgaaggcgg
    30541 ttttaaggaa taaacaatgc aaagtgttga tgtagccatt gttggcggcg gcatggtggg
    30601 gctggcggtt gcctgcggct tacaggggag cggcttacgc gttgccgtac tggagcagcg
    30661 cgtaccggaa cctctggcgg cggatgcacc accacaactg cgcgtttcgg ctatcaatgc
    30721 cgccagcgaa aaattactca cccgtcttgg cgtctggcag gacattctct ctcgtagggc
    30781 tagttgttat cacggtatgg aagtgtggga caaagacagt tttggtcaca tttcgtttga
    30841 cgatcaaagc atgggctata gccatcttgg gcatatcgtt gaaaactcag tgattcacta
    30901 cgcgctgtgg agcaaagcgc agcaggcgtc agatatcacc ctgttggccc ccgcagaatt
    30961 acagcaggtc gcctggggag aaaatgaaac tttcctgacg ctgaaagatg gcagcatgtt
    31021 aacggcgcgt ctggtgattg gcgcggacgg cgctaattcc tggttgcgca acaaagcaga
    31081 tattccgctg actttctggg attatcagca tcacgcgctg gtagcgacca ttcgcacgga
    31141 agaaccgcat gatgcggtgg cgcggcaggt tttccatggc gaaggcattc tggccttttt
    31201 accgcttagc gatccgcatc tttgctcgat tgtctggtca ctgtcgccag aggaagcgca
    31261 gcggatgcag caggcaagtg aagacgaatt taatcgcgcg ttaaatatcg cttttgataa
    31321 tcgcctgggc ttatgcaagg ttgagagcgc gcgtcaggtg ttcccactga cggggcgtta
    31381 tgcgcgccag tttgccgcgc accgtctggc gctggtgggc gacgccgcgc ataccattca
    31441 cccgctggcg gggcaggggg taaatcttgg ctttatggat gctgcagagc tgattgctga
    31501 actgaaacgg ttgcatcgtc agggtaaaga catcgggcag tacatttatc tgcgtcgcta
    31561 tgagcgtagc cgcaagcaca gttcggcgct gatgctggct ggtatgcagg gattccgcga
    31621 tctgttttcc ggtaccaatc cggcgaaaaa actgctgcgt gatattggtt tgaaactggc
    31681 cgacacgctt cctggcgtta aaccacaact catccgccag gcaatgggat taaacgattt
    31741 gcctgaatgg ctgcgttaaa aatttctctt ctgttgttta tttgataccc atcacacttt
    31801 catctcccgg ttttttcgcc gggagatttt cctcatttga aataaactaa tttcacctcc
    31861 gttttcgcat tatattttct aatgccatga ttttttgatt tagtgttttt tgacattttt
    31921 ttagttctta atattgcctt attcaaatta actttctaat ggcatcatct ttatatagaa
    31981 actagtgtgt tttttggttt tttattctgt cgcgattttg gcgtttttta accataagct
    32041 aatgtgatga tcaattttac cttatggtta acagtctgtt tcggtggtaa gttcaggcaa
    32101 aagagaacga ttgcgttggg gaccgggagt ggctccgatg ctgggtttcg tggtgataat
    32161 ttcaccatga aaagttgtca gccccgctta ttcaatgagg acaagatggc acaacagact
    32221 cctttgtacg aacaacacac gctttgcggc gctcgcatgg tggatttcca cggctggatg
    32281 atgccgctgc attacggttc gcaaatcgac gaacatcatg cggtacgtac cgatgccgga
    32341 atgtttgatg tgtcacatat gaccatcgtc gatctccgcg gcagccgcac ccgggagttt
    32401 ctgcgttatc tgctggcgaa cgatgtggcg aagctcacca aaagcggcaa agccctttac
    32461 tcggggatgt tgaatgcctc tggcggtgtg atagatgacc tcatcgtcta ctactttact
    32521 gaagatttct tccgcctcgt tgttaactcc gccacccgcg aaaaagacct ctcctggatt
    32581 acccaacacg ctgaaccttt cggcatcgaa attaccgttc gtgatgacct ttccatgatt
    32641 gccgtgcaag ggccgaatgc gcaggcaaaa gctgccacac tgtttaatga cgcccagcgt
    32701 caggcggtgg aagggatgaa accgttcttt ggcgtgcagg cgggcgatct gtttattgcc
    32761 accactggtt ataccggtga agcgggctat gaaattgcgc tgcccaatga aaaagcggcc
    32821 gatttctggc gtgcgctggt ggaagcgggt gttaagccat gtggcttggg cgcgcgtgac
    32881 acgctgcgtc tggaagcggg catgaatctt tatggtcagg agatggacga aactatttct
    32941 cctttagccg ccaacatggg ctggactatc gcctgggaac cggcagatcg tgactttatc
    33001 ggtcgtgaag ccctggaagt gcagcgtgag catggtacag aaaaactggt tggtctggtg
    33061 atgaccgaaa aaggcgtgct gcgtaatgaa ctgccggtac gctttaccga tgcgcagggc
    33121 aaccagcatg aaggcattat caccagcggt actttctccc cgacgctggg ttacagcatt
    33181 gcgctggcgc gcgtgccgga aggtattggc gaaacggcga ttgtgcaaat tcgcaaccgt
    33241 gaaatgccgg ttaaagtgac aaaacctgtt tttgtgcgta acggcaaagc cgtcgcgtga
    33301 tttacttttt tggagattga ttgatgagca acgtaccagc agaactgaaa tacagcaaag
    33361 aacacgaatg gctgcgtaaa gaagccgacg gcacttacac cgttggtatt accgaacatg
    33421 ctcaggagct gttaggcgat atggtgtttg ttgacctgcc ggaagtgggc gcaacggtta
    33481 gcgcgggcga tgactgcgcg gttgccgaat cagtaaaagc ggcgtcagac atttatgcgc
    33541 cagtaagcgg tgaaatcgtg gcggtaaacg acgcactgag cgattccccg gaactggtga
    33601 acagcgaacc gtatgcaggt ggctggatct ttaaaatcaa agccagcgat gaaagcgaac
    33661 tggaatcact gctggatgcg accgcatacg aagcattgtt agaagacgag taacggcttt
    33721 attcctcttc tgcgggagag gatcagggtg aggaaaattt atgcctcacc ctcactctct
    33781 tcgtaaggag agaggttcac aattcactgc acgtttcagg aaccatcgct catgacacag
    33841 acgttaagcc agcttgaaaa cagcggcgct tttattgaac gccatatcgg accggacgcc
    33901 gcgcaacagc aagaaatgct gaatgccgtt ggtgcacaat cgttaaacgc gctgaccggc
    33961 cagattgtgc cgaaagatat tcagcttgcg accccgccgc aggttggcgc accggcgacc
    34021 gaatacgccg cactggcaga actcaaggct attgccagtc gcaataaacg cttcacgtct
    34081 tacatcggca tgggttacac cgccgtgcag ctaccgccgg ttatcctgcg taacatgctg
    34141 gaaaatccgg gctggtatac cgcgtacact ccgtatcaac ctgaagtctc ccagggccgc
    34201 cttgaagcac tgctcaactt ccagcaggta acgctggatt tgactggact ggatatggcc
    34261 tctgcttctc ttctggacga ggccaccgct gccgccgaag caatggcgat ggcgaaacgc
    34321 gtcagcaaac tgaaaaatgc caaccgcttc ttcgtggctt ccgatgtgca tccgcaaacg
    34381 ctggatgtgg tccgtactcg tgccgaaacc tttggttttg aagtgattgt cgatgacgcg
    34441 caaaaagtgc tcgaccatca ggacgtcttc ggcgtgctgt tacagcaggt aggcactacc
    34501 ggtgaaattc acgactacac tgcgcttatt agcgaactga aatcacgcaa aattgtggtc
    34561 agcgttgccg ccgatattat ggcgctggtg ctgttaactg cgccgggtaa acagggcgcg
    34621 gatattgttt ttggttcggc gcaacgcttc ggcgtgccga tgggctacgg tggcccacac
    34681 gcggcattct ttgcggcgaa agatgaatac aaacgctcaa tgccgggccg tattatcggt
    34741 gtatcgaaag atgcagctgg caataccgcg ctgcgcatgg cgatgcagac tcgcgagcaa
    34801 catatccgcc gtgagaaagc gaactccaac atttgtactt cccaggtact gctggcaaac
    34861 atcgccagcc tgtatgccgt ttatcacggc ccggttggcc tgaaacgtat cgctaaccgc
    34921 attcaccgtt tgaccgatat cctggcggca ggcctgcaac aaaaaggtct gaagctgcgc
    34981 catgcgcact atttcgacac tctgtgtgtg gaagtggccg acaaggcggg cgtactggcg
    35041 cgtgccgaag cggctgaaat caacctgcgt agcgatatcc tgaacgcggt tgggatcacc
    35101 cttgatgaaa ccaccacgcg tgaaaacgta atgcagcttt tcagcgtgct gctgggcgat
    35161 aaccacgggc tggagatcga cacgctggac aaagacgtgg ctcacgacag ccgctctatt
    35221 cagcctgcga tgctgcgcga cgacgaaatc ctcactcatc cggtgtttaa tcgctaccac
    35281 agcgaaaccg aaatgatgcg ctatatgcac tcgctggagc gtaaagatct ggcgctgaat
    35341 caggcgatga tcccgctggg ttcctgcacc atgaaactga acgccgccgc cgagatgatc
    35401 ccaatcacct ggccggaatt tgccgaactg cacccgtttt gcccgccgga acaggctgaa
    35461 ggttatcagc agatgattgc gcagctggct gactggctgg tgaaactgac cggttacgac
    35521 gccgtttgta tgcagccgaa ctccggcgca cagggcgaat acgcgggcct gctggcgatt
    35581 cgtcattatc atgaaagccg caacgaaggg catcgcgata tctgcctgat cccggcttct
    35641 gcgcacggaa ctaaccccgc ttctgcacat atggcaggaa tgcaggtggt ggttgtggcg
    35701 tgtgataaaa acggcaacat cgatctgact gatctgcgcg cgaaagcgga acaggcgggc
    35761 gataacctct cctgtatcat ggtgacttat ccttctaccc acggcgtgta tgaagaaacg
    35821 atccgtgaag tgtgtgaagt cgtgcatcag ttcggcggtc aggtttacct tgatggcgcg
    35881 aacatgaacg cccaggttgg catcacctcg ccgggcttta ttggcgcgga cgtttcgcac
    35941 ctcaacctgc ataaaacttt ctgcattccg cacggcggtg gtggtccggg tatgggaccg
    36001 atcggtgtga aagcgcatct ggcaccgttt gtaccgggtc atagcgtggt gcaaatcgaa
    36061 ggcatgttaa cccgtcaggg cgcagtttct gcggcaccgt tcggtagcgc ctctatcctg
    36121 ccaatcagct ggatgtacat ccgcatgatg ggcgcagaag ggctgaaaaa agcaagccag
    36181 gtggcaatcc tcaacgccaa ctatattgcc agccgcctgc aggatgcctt cccggtgctg
    36241 tataccggtc gcgacggtcg cgtggcgcac gaatgtattc tcgatattcg cccgctgaaa
    36301 gaagaaaccg gcatcagcga gctggatatt gccaagcgcc tgatcgacta cggtttccac
    36361 gcgccaacga tgtcgttccc ggtggcgggt acgctgatgg ttgaaccgac tgaatctgaa
    36421 agcaaagtgg aactggatcg ctttatcgac gcgatgctgg ctatccgcgc agaaattgac
    36481 caggtgaaag ccggtgtctg gccgctggaa gataacccgc tggtgaacgc gccgcacatt
    36541 cagagcgaac tggtcgccga gtgggcgcat ccgtacagcc gtgaagttgc ggtattcccg
    36601 gcaggcgtgg cagacaaata ctggccgacg gtgaaacgtc tggatgatgt ttacggcgac
    36661 cgtaacctgt tctgctcctg cgtaccgatt agcgaatacc agtaattcac tgattcgact
    36721 attttctaaa ggcgcttcgg cgccttttta gtcagatgac aaagtacaaa agtgctcaga
    36781 cagtcccctc gcccctttgg ggagagggtg aggggaacag gccggcactg gcgcgaatat
    36841 ttaccctcac cccggccctc tccctgaaag ggcgaggggg aaaagcgtgc caacattgaa
    36901 gattgagcca gtttgttagc aatctcaaag atacgtcaac gaatgaattt ttctcggaaa
    36961 aacaaatggc tatagcactt gtgaccggtg gcagtcgcgg catcgggcgg gcaactgcat
    37021 tactgttggc gcaagaaggg tatacggtgg cggttaatta tcaacaaaac ctccacgcgg
    37081 cgcaggaagt gatgaactta ataacgcaag ccggtggcaa agcattcgtg ctccaggcgg
    37141 atatcagcga cgaaaaccag gtcgttgcga tgtttacagc aatcgatcag cacgatgaac
    37201 cgctagcagc gctggtcaat aacgccggga tcttgtttac ccagtgcacc gttgaaaacc
    37261 ttaccgcaga gcgaatcaac cgagtacttt ccaccaacgt gacgggatat tttctctgct
    37321 gccgcgaggc ggtaaaacgc atggcgctta aaaatggtgg cagtggcggc gctatcgtca
    37381 atgtctcttc ggtggcctca cggttgggtt cgccagggga atatgttgat tacgcggcat
    37441 cgaaaggggc gattgatacg ttaaccaccg gactatcgct ggaagtcgcc gcgcagggga
    37501 tccgggttaa ctgcgtgcgg ccagggttta tttataccga aatgcacgcc agcggcggcg
    37561 agcctggacg cgtcgatcgc gttaagtcga acatccccat gcagcgtggt ggacaggcag
    37621 aagaggtcgc gcaggccatt gtctggctac taagtgataa agcctcttac gtcacgggaa
    37681 gttttatcga tttggcgggc gggaaataaa acagggaagt tgtctgaccg gatgcaacaa
    37741 gtattgcatc cggtacttca tcgacttaaa gcttctcgcc gttgctggca atcacctctt
    37801 tgtaccagtt aaagctcttc ttacgtgaac gcgacatatc gccagtaccg tcgtcatgtt
    37861 tattcacata gataaagccg tagcgtttgc tgtactgccc ggtggtgaac gatacgcagt
    37921 cgatgcagcc ccacggtgtg tagcccatca gatccacacc atcgtaagtc actgcttttt
    37981 tcatctcttc aatatgggcg cgcaggtagt caatgcggta gtcgtcgttg atgctgccat
    38041 cttcttccac tttgtcgtaa gcgccaaaac cgttttcgac aataaacagc ggcctctgat
    38101 aacgctcata cagttcgcaa agggcatagc gcagacctac tggatcaatc tgccagcccc
    38161 agtcagacgc tttaacatac gggttcggta cgctgccttc aaaaccagag atcgcatcgc
    38221 cggtgccgcc ttcggccttc actgcgttgg tcatgtaata gctgaaacca agataatcgc
    38281 aggtgccttc acgcagtaca tcgagatcgc cgtcttccat tttgatgtta aatccgcgac
    38341 gctcccactc gttcaacaca taggacgggt aatagccgcg tagctgcaca tcggtaaaga
    38401 cgtagcgttc gcgcatcgac tcctgagcga acatcacatc gtccgggtta cagcagtagg
    38461 gatagagcgg caccatcgcc agcatacagc cgactttcat ctccgggtta atgcgacgcg
    38521 cagctttcac cgccagggcg ctggcgacaa actggtgatg cagcacctga tacatcgtct
    38581 cttccgggtt ctcatgctcg gtataaacca cgccggagca gcagtaaccg aacagcggtg
    38641 cacgccagtt acgctggttg ttaatttcgt tgaaggtcat ccagtatttg actttatgct
    38701 tatagcgttc aaacaccact tccgcgaaac ggacaaagaa atcaaccact ttacggttgg
    38761 tccagctacc gtattgctgc accagatgca gcggcatttc aaagtgggag agggtgatca
    38821 ccggttcgat gttgtatttc agcagttcat cgaacatatc atcgtagaac ttcagccctt
    38881 cttcgtttgg ctgagcttca tcaccttttg gaaaaatacg cgtccaggcg atggaagtcc
    38941 gaaaacattt gaagcccatt tcggcaaata gcttgatgtc ttccttgtag tgaccataaa
    39001 aatcaacggc ttcatggttt ggatagtatt tgcctggcaa gacttctttg gtgatttcgc
    39061 gcggcacgcc gtgtgcgcca ccggtcagaa cgtcacaaat gctcggccct ttgccgcctt
    39121 tgttccagcc gccttcgacc tgatgagcgg caactgcgcc gccccataag aaatctttcg
    39181 gtaaggtgag ttttttcact atcataggct ccagatgaat caattcttac aggaaatagt
    39241 accatgcagc caaacgacat cacttttttt caacgtttcc aggatgacat tctggctgga
    39301 cgtaaaacca tcaccatccg cgacgaatct gaatcgcact ttaaaacggg cgatgtgctg
    39361 cgcgttgggc gctttgaaga tgatggctat ttttgcacca tcgaagtcac cgcaacctca
    39421 accataacgc tggagacgct gacggaaaaa catgcagagc aggaaaatat gaccctgcct
    39481 gaactgaaaa aggtcattgc cgacatctat cccggccaga cacagtttta tgtgattgaa
    39541 tttaaatgcc tttaaattga actcacgcct gttagttgaa atttcgcatt taatttcatg
    39601 atttttcgga gattagtcca aaatcagaat ttattttagc taacaggtgt tcactggaac
    39661 tattctcagt tacgctggag aggtatacat gtgcgtgtac gtttctccgg agtaagttat
    39721 ggttcagaag cccctcatta agcagggata ttcgctggca gaggaaattg ccaacagcgt
    39781 cagtcacggc attgggctgg tgtttggtat cgttgggctg gtgttgctac tggttcaggc
    39841 ggtggatctc aatgccagcg ccacggcgat aaccagttat agcctatatg gcggcagtat
    39901 gatcctgctg ttcctcgctt cgacgctcta tcacgccatt ccccatcaac gggcaaaaat
    39961 gtggctgaag aaatttgacc attgcgccat ttacctgttg attgccggaa cctatacacc
    40021 gtttttgctg gtggggttag attctccgtt agcgcgcgga ttgatgattg ttatctggag
    40081 cctggcattg ctggggattc tgttcaaact gaccatcgcg caccgattta aaattttatc
    40141 tctggtgact tatctggcga tgggctggtt gtcgctggtg gtaatttatg aaatggcagt
    40201 taagctcgcg gcaggcagcg ttaccttact ggcggtaggc ggcgtggttt attcgctcgg
    40261 ggtgattttc tatgtctgca aacgcattcc gtacaatcat gccatctggc acggctttgt
    40321 actcggcggt agtgtgtgcc actttctggc gatctatttg tatattgggc aggcgtaatt
    40381 gctgtgcctt tgtctgcatg aaaagacaca tcagtgtcgc ttcaggcaat agatgcccga
    40441 agcgatatag aaatttactc ttcgagcgaa tacggcagcg gctcgatatg cagtgtattt
    40501 gcatcgtcgc gcacgcggaa gatgctgtcc ggttccatat cgttattcat caccacctgc
    40561 accacgacct gaccatcttc cagtttgacc gcagccagca ccgtaccggt acgacgccag
    40621 ttttcgccca ttttcagctc taagtcttca cctgcttctg gcagtcggct ggcgctacct
    40681 gccagtaacc agagcgcacg tttgttggca ccgcggaatt tggcccgcgc caccatctct
    40741 tgtccggtat aacagccttt cttaaagctg ataccgccca gcgcctggag attggtcgcc
    40801 tgtgggataa actgcccgct gttggcggca tcaatcaccg ggaaacccgc ttcaatgttt
    40861 aatgccagcc actgttggct attgttcagt tccgcttcac cgcgcagttt atcggtcagc
    40921 atattagcag tagcttcatc ggttacgatc aggaaacgtt ctgccgggtg ttcaaaccat
    40981 agcaaagtgg tcgcgccttc tttgactacc tgtttttctt tcgaaggcag ttcgctaaag
    41041 agatttgcca gcgcggcgcg cgcctgaaaa ccggcaacac caagcagcac acgctcgtcg
    41101 tctggcgcga tggtcacttt agagaatacc gcatattttt tcagttcagt cagctgcggt
    41161 tcacgcacgc tgcgccgttc aatccatgca aagccatcgc cgtcgcggaa cagacgtaaa
    41221 ttgctccaca ttttaccttt ggcgtcgcaa tgggcggcga gcaggtgctg atcttctgcc
    41281 atctggctga catctgctgt cacctgaccc tgcatatatt tttcgctgtc cgcgccagta
    41341 atggtggcaa gcgcccagtc atcaagcgtc atcagcgtca gcggtaaacg ggcagaagcc
    41401 gtaggctgac ggggaggaaa aggtgtaaaa gccataatag agtcctgagt tgcttaacgg
    41461 cgtattaatg actaatggta aaagagctat gaggcaatgc aagtgctttc actacgcgat
    41521 ctgtgccttc tgcgaggcga cttccaaaaa aatgaagcca ttgaattgtt gtgaattaat
    41581 ttcgcgatcg cgatggtgtt tactgatatt cccgtaaaag aaggcgaaaa acacgttaca
    41641 atagccgggt actggatttt cgtgagacag gaagaagatg gacattaaca acaaagcccg
    41701 cattcattgg gcatgccgcc gtggtatgcg cgaactcgat atttcaatca tgccgttttt
    41761 cgaacatgag tacgacagct taagcgatga cgaaaaacgc atctttattc gtctgctgga
    41821 atgtgacgat ccggacctgt ttaactggct gatgaatcac ggtaaaccgg ccgatgcaga
    41881 actggaaatg atggtccgac tcatccagac acggaaccgg gaacgtggtc ctgtggcaat
    41941 ctgatttgcg cgtctcctgg cgcgcacagt ggctttcctt gctgattcat gggctggttg
    42001 ccgctgttat tttactcatg ccctggccac tcagttacac cccgttatgg atggtgttac
    42061 tttcgctggt ggtgtttgat tgcgttcgca gccagcggcg tattaatgct cgccaggggg
    42121 aaattcgctt gttgatggac gggcgtttgc gttggcaagg gcaggagtgg tgcatcgtca
    42181 aagcaccgtg gatgattaag agcggcatga tgctgcgttt acgttctgat ggcggtaaac
    42241 ggcaacattt atggctggca gccgacagca tggacgaagc cgaatggcgg gatttacggc
    42301 ggattttgtt gcaacaagag acgcaaagat aaagatgacg gcaaagcata tgcgctaagc
    42361 cgtcagtgag atcaggcgta atgctctgcc atttcgttga ggatttgctc gcaccagctc
    42421 tgaatacgct cgtcgctaag gtcatactgg ttagtttcat ccagcgccag acccacgaac
    42481 agttgcccgt cagcaatcac cggtttcggg ctggtaaatt catatccttc cgttggccag
    42541 tagccgacga acttcacgcc tttggtcgag agtttgtcat gcagcatacc gagcgcatcg
    42601 aggaaccact cgccgtatcc cagttgatcg ccaagcccat acagcgcaac aattttacct
    42661 tcaaggttca ggtcgtcgag ctgatcccag acggcttccc agtcttcctg gatttcacca
    42721 aaatcccagg tcgggatacc cagaatgagc acatcgtact gctccattaa tttcggggag
    42781 tcgtccttga ggttatgtaa ggtcaccagt tctgggccga taatatcgcg gattttttct
    42841 gccgccattt cggtgtaaca ggtgctggaa ccgtaaaaaa gacccatatt cataacgtaa
    42901 gcttctcgat tctgctgtgg cttttgcggc tagtgtatca gaatcgcttt agtcacggca
    42961 caataaggca taatggatca aatgagtgac cataaggggc gcaagtgaaa caggatctgg
    43021 cacgcattga gcagtttctt gatgctctgt ggctggaaaa aaatctggct gaaaatacgt
    43081 tgaacgctta ccgtcgcgat ctgtcaatga tggtggagtg gttgcatcac cgcgggttga
    43141 cgctggcgac ggcgcaaagt gacgatttgc aggcattact ggcagaacgg ctggagggcg
    43201 ggtataaagc caccagctca gcgcgtttgc tgagtgcagt gcgccgattg ttccagtatc
    43261 tttatcgcga aaagtttcgt gaagacgatc ccagtgcgca tctcgcttca ccgaaattgc
    43321 cccagcgttt gccaaaagat ttaagcgaag cgcaggtcga acgtttatta caggcaccat
    43381 taattgatca gccactggag ctacgcgata aagccatgct tgaagtgttg tatgctaccg
    43441 ggctgcgtgt ctctgaactg gtcggactga caatgagtga tatcagcctg cgtcagggcg
    43501 tagtgcgggt cattggtaaa ggcaacaaag agcgcctggt accgttaggt gaagaggcgg
    43561 tttactggct ggaaacctat ctggaacatg ggcgtccgtg gctgctgaat ggtgtgtcaa
    43621 ttgacgtgtt gtttcccagc cagcgtgcgc agcagatgac gcgacagacc ttctggcacc
    43681 gcattaaaca ttatgctgtg ctggcgggta tcgacagcga aaagctgtca ccgcatgtat
    43741 tgcgtcacgc ttttgccacc catttattaa atcatggtgc ggatttacgc gtggtgcaga
    43801 tgctactggg ccacagcgac ctctccacca cgcaaattta tacgcatgtc gctaccgagc
    43861 gtctgcggca acttcatcaa cagcatcacc cgcgggcgtg atgtctgaaa agaacgggaa
    43921 gatttatgaa gaaaggtttt atgttgttta ctttgttagc ggcgttttca ggttttgctc
    43981 aggctgatga cgcggcaatt caacaaacgt tagccaaaat gggcatcaaa agcagcgata
    44041 ttcagcccgc gcccgtagct ggcatgaaga cagttctgac taacagcggc gtgttgtaca
    44101 tcaccgatga tggtaaacat atcattcagg ggccaatgta tgacgttagc ggcacggctc
    44161 cggtcaatgt caccaataag atgctgttaa agcagttgaa tgcgcttgaa aaagagatga
    44221 tcgtttataa agcgccgcag gaaaaacacg tcatcaccgt gtttactgat attacctgtg
    44281 gttactgcca caaactgcat gagcaaatgg cagactataa cgcgctgggg atcaccgtgc
    44341 gttatcttgc tttcccgcgc caggggctgg acagcgatgc agagaaagaa atgaaagcta
    44401 tctggtgtgc gaaagataaa aacaaagcgt ttgatgatgt gatggcaggt aaaagcgtcg
    44461 caccagccag ctgcgacgtg gatattgccg accattacgc acttggcgtc cagcttggcg
    44521 ttagcggtac tccggcagtt gtgctgagca atggcacact tgttccgggt taccagccgc
    44581 cgaaagagat gaaagaattc ctcgacgaac accaaaaaat gaccagcggt aaataattcg
    44641 cgtgaaacaa cagatacaac ttcgtcgccg tgaagtcgat gaaacggcag acttgcccgc
    44701 tgaattgcct cccttgctgc gccgtttata cgccagccgg ggcgtgcgca gtgcgcaaga
    44761 actggaacgc agtgttaaag gtatgttgcc ctggcagcaa ctgagcggcg tcgaaaaggc
    44821 cgttgagatc ctttacaacg cttttcgcga aggaacgcgg attattgtgg tcggcgattt
    44881 tgacgccgac ggcgcgacca gcacggctct aagcgtgctg gcgatgcgct cgcttggttg
    44941 cagcaatatc gactacctgg taccaaaccg tttcgaagac ggttacggct taagcccgga
    45001 agtggtcgat caggcccatg cccgtggcgc gcagttaatt gtcacggtgg ataacggtat
    45061 ttcctcccat gcgggggttg aacacgctcg ctcgttgggc attccggtta ttgttaccga
    45121 tcaccatttg ccaggcgaaa cattacccgc ggcggaagcg atcattaacc ctaacttgcg
    45181 cgactgtaat ttcccgtcga aatcactggc aggcgtgggt gtggcgtttt atctgatgct
    45241 ggcgctgcgc acctttttgc gcgatcaggg ctggtttgat gagcgtggca tcgcaattcc
    45301 taacctggca gaactgctgg atctggtagc gctggggaca gtagcggacg tcgtgccgct
    45361 ggacgctaat aatcgcattc tgacctggca ggggatgagt cgcatccgtg ccggaaagtg
    45421 ccgtccgggg attaaagcgc tgctggaagt ggcaaatcgc gatgcgcaaa aactcgccgc
    45481 cagcgattta ggttttgcgc tggggccacg tctcaatgct gccgggcgac tggacgatat
    45541 gtccgtcggt gtggcgctgt tgctgtgcga caacatcggc gaagcgcgcg tgctggcaaa
    45601 tgaactcgat gcgctaaacc agacgcgaaa agagatcgaa caaggaatgc aagttgaagc
    45661 cctgaccctg tgcgagaaac tggagcgaag tcgcgacacg ctacccggcg ggctggcaat
    45721 gtaccacccc gaatggcatc agggcgttgt cggtattctg gcttcgcgca tcaaagagcg
    45781 ttttcaccgt ccggttatcg cctttgcgcc agcaggtgat ggtacgctga aaggttcagg
    45841 tcgctccatt caggggctgc atatgcgtga tgcactggag cgattagaca cactctaccc
    45901 tggcatgatg ctgaagtttg gcggtcatgc gatggcggcg ggtttgtcgc tggaagagga
    45961 taaattcgaa ctctttcaac aacggtttgg cgaactggtt acagagtggc tggacccttc
    46021 gctattgcaa ggcgaagtgg tgtcagacgg tccgttaagc ccggccgaaa tgaccatgga
    46081 agtggcgcag ttgctgcgcg atgctggccc gtgggggcag atgttcccgg agccgctgtt
    46141 tgacggtcat ttccgtctgc tgcaacagcg gctggtgggc gaacgtcatt tgaaggtgat
    46201 ggtcgaaccg gtcggcggcg gtccactgct ggatggtatt gcttttaatg tcgataccgc
    46261 cctctggccg gataacggcg tgcgtgaagt gcaactggct tataagctcg atatcaacga
    46321 gtttcgcggc aaccgcagcc tgcaaattat catcgacaat atctggccaa tttagcgtca
    46381 tcttctctat aaaaaagagc gtggattggg tacaatcccg ctcttatcac cgcattttga
    46441 ctagctcaat aaaagaaatc agaccatgtt tgaaattaat ccggtaaata atcgcattca
    46501 ggacctcacg gaacgctccg acgttcttag ggggtatctt tgactacgac gccaagaaag
    46561 agcgtctgga agaagtaaac gccgagctgg aacagccgga tgtctggaac gaacccgaac
    46621 gcgcacaggc gctgggtaaa gagcgttcct ccctcgaagc cgttgtcgac accctcgacc
    46681 aaatgaaaca ggggctggaa gatgtttctg gtctgctgga actggctgta gaagctgacg
    46741 acgaagaaac ctttaacgaa gccgttgctg aactcgacgc cctggaagaa aaactggcgc
    46801 agcttgagtt ccgccgtatg ttctctggcg aatatgacag cgccgactgc tacctcgata
    46861 ttcaggcggg gtctggcggt acggaagcac aggactgggc gagcatgctt gagcgtatgt
    46921 atctgcgctg ggctgaatcg cgtggtttca aaactgaaat catcgaagag tcggaaggtg
    46981 aagtggcggg tattaaatcc gtgacgatca aaatctccgg cgattacgct tacggctggc
    47041 tgcgtacaga aactggcgtt caccgcctgg tgcgtaaaag cccgtttgac tccggcggtc
    47101 gtcgccacac atcgttcagc tctgcgtttg tttacccgga agttgatgat gatattgata
    47161 tcgaaatcaa cccggcggat ctgcgcattg acgtttatcg cgcgtccggc gcgggcggtc
    47221 agcacgttaa ccgtaccgaa tctgcggtgc gtattaccca catcccaacc gggatcgtga
    47281 cccaatgcca gaacgaccgt tcccagcaca agaacaaaga ccaggccatg aagcagatga
    47341 aagcgaagct ttatgaactg gagatgcaga agaaaaatgc cgagaaacag gcgatggaag
    47401 ataacaaatc cgacatcggc tggggcagcc agattcgttc ttatgtcctt gatgactccc
    47461 gcattaaaga tctgcgtacc ggggtagaaa cccgcaacac gcaggccgtg ctggacggca
    47521 gcctggatca atttatcgaa gcaagtttga aagcagggtt atgaggaacc aacatgtctg
    47581 aacaacacgc acagggcgct gacgcggtag tcgatcttaa caatgaactg aaaacgcgtc
    47641 gtgagaagct ggcgaacctg cgcgagcagg ggattgcctt cccgaacgat ttccgtcgcg
    47701 atcatacctc tgaccaattg cacgcagaat tcgacggtaa agagaacgaa gaactggaag
    47761 cgctgaacat cgaagtcgcc gttgctggcc gcatgatgac ccgccgtatt atgggtaaag
    47821 cgtctttcgt taccctgcag gatgtgggtg gccgcattca gctgtacgtt gcccgtgacg
    47881 atctgccgga aggcgtttac aacgagcagt tcaaaaaatg ggacctcggt gacatcctcg
    47941 gcgcgaaagg taaactgttc aaaaccaaaa ccggcgaact gtctatccac tgtaccgagc
    48001 tgcgtctgct gaccaaagca ctgcgtccgc tgccggataa attccacggc ttgcaggatc
    48061 aggaagcgcg ctatcgtcag cgttatctgg atctcatctc taacgatgaa tcccgtaaca
    48121 cctttaaagt gcgctcgcag atcctctctg gtattcgcca gttcatggtg aaccgcggct
    48181 ttatggaagt tgaaacgccg atgatgcagg tgatccctgg cggtgccgct gcgcgtccgt
    48241 ttatcaccca ccataacgcg ctggatctcg acatgtacct gcgtatcgcg ccggaactgt
    48301 acctcaagcg tctggtggtc ggtggcttcg agcgtgtatt cgaaatcaac cgtaacttcc
    48361 gtaacgaagg tatctccgta cgtcataacc cagagttcac catgatggaa ctctacatgg
    48421 cttacgcaga ttacaaagat ctgatcgagc tgaccgaatc gctgttccgt actctggcac
    48481 aggatattct cggtaagacg gaagtgacct atggcgacgt gacgctggac ttcggtaaac
    48541 cgttcgaaaa actgaccatg cgtgaagcga tcaagaaata tcgcccggaa accgacatgg
    48601 cggatctgga taacttcgac tctgcgaaag cgattgctga atctatcggt atccacgttg
    48661 agaagagctg gggtctgggc cgtatcgtta ccgagatctt cgaagaagtg gcagaagcac
    48721 atctgattca gccgaccttc attactgaat atccggcaga agtttctccg ctggcgcgtc
    48781 gtaacgacat taacccggaa atcacagacc gctttgagtt cttcatcggt ggtcgtgaaa
    48841 tcggtaacgg ctttagcgag ctgaatgacg cggaagatca ggcgcaacgc ttcctggatc
    48901 aggttgccgc gaaagacgca ggtgacgacg aagcgatgtt ctacgatgaa gattacgtta
    48961 ccgcactgga acatggctta ccgccgacag caggtctggg gattggcatc gaccgtatgg
    49021 taatgctgtt caccaacagc cataccatcc gcgacgttat tctgttcccg gcgatgcgtc
    49081 cggtgaaata agcattacgt tatgctcaca accccggcaa atgtcggggt tttttattta
    49141 agctgggtaa atgcagataa tcgtattctg gcttcgcgat ttgtcgcctg catcaccatc
    49201 cacggactga acgcccacgg cgtggcatca ataccgtgta atacatcagc taaatcacac
    49261 cattgataat ccatcacttc atcatcgttg atctgtaacg cactggtggt gcgtgcggca
    49321 aataccggac acacttcatt ttccacaatg ccactcggat cggtggcgcg gtagcgaaag
    49381 tcaggataga tagattcagg aggcgtaatt tccacgccaa gctcataacg gcaacggcgg
    49441 atcaccgcgt cttcgctgct ttctcccagt tgtgggtgcc cacaaaccga gttagtccac
    49501 acgccaggcc acgctttttt gctcagtgcg cggcgggtaa ctaataattg ccccttggca
    49561 ttaaacagcc aactggagaa cgcgagatgt aagagggtgt ctgccgtgtg tgcggcatac
    49621 ttttccagcg taccagtggg aactccctgt gcattcaata aaatgacgtg ttccgtttgc
    49681 ataatttctc acatgtaatt ctgatcactc atcattatag ataattgaag agtgaaatga
    49741 ttaaccaagt gagcgtttat cgacaaccgc ccgttttgag cggatgccga caggtaaaaa
    49801 ccatttaaaa aagtagcatc atatatttga agcgactttc aatggccatt gcaacacagt
    49861 cagaaatgac aggaatagag agagtaaaaa gcaacagcag actgaatata gcgcgcatta
    49921 aaaaattcat attattctcc atgctcattt ttcttcagct tgcgcatcag aagccacata
    49981 cgtactgtcc tgacttttaa atctttatca gagacggatt ccttcaccag gtcagcatga
    50041 tgctggtagc cattaaagaa gacattcagc acaacggcgc taagggttgc gagcataatg
    50101 ccgctatgca gcaacggttg cagtacggcc ggtaacttag aaaagaaatc gtgagagagc
    50161 gtcggagtca tgccaacgcc gagactgatc gccacaatat agaggttgta acggttggtg
    50221 gtgtagttac agcgcgacag aattcgaatc cctgtcgcca gtaccatgcc gaacatcacc
    50281 agcccagcac cgcccagcac aaattgcgga atggaggcga ccagcaccgc catttttggc
    50341 accatgccaa acaggattaa tataattccc gaagaaatac acacccagcg gctatgaacg
    50401 cgcgtcacgc taaccaggcc aacgttttgt gaaaatgacg tgtgggggaa gctgttaaac
    50461 gttccgccta tcattgtccc tacgccatcg acacgcagcc cgcgaataat atcgtgtgaa
    50521 gagagtttac gaccgactat ttcacccagt gccaggaaca tccccatcga ctcgataaac
    50581 acgatgatta acacggcagt catggtcaga atggaaacgg gatcgaaaat cggcatacca
    50641 aatgacatcg gcgtgacaat cgcaaaccat gaagcatcat gtagcccgga taaattgact
    50701 tcattcatca tccacgaaag taaaaagcca aatacaatcc ccagtaatac ggcgacgttg
    50761 gacataaatc ctttcgcata gcgagtaatg agcaagataa aaattaagac agcaaaggag
    50821 atacctaaat aaacgggatt accatattgc ggattccctt tacctccggc ggcccagtca
    50881 atacccacct gaatgatgct aagcccaata gaagtaataa ccacaccggt aaccagtggc
    50941 gggaataaag gcatcaagcg accgataagt ggcgctaata atgtggtgat aaaacccgcg
    51001 gcgatagtgg caccaaatat ccccagcagg ccgatatccg ggttcatccc aatggctatc
    51061 attggtgtta cagcagcaaa ggtcaccgac ataatcaccg gcaggcggat ccccataaag
    51121 cggccgatac cgatacattg caataatgtg acgatcccgc agcaaaagag atccgagcta
    51181 atgagcatcg caatagcttc ttttgagagg cccagtcggt caccaatcat aagaggaaca
    51241 gcgactgcac ctgcgtacat gacaaggacg tgttgcagac cgagtatgat cagctttcct
    51301 ggtgataata tgcggtcaac ctcatcagtt gggcggtctt gcccagaaga tgagggaagt
    51361 tgggaatcta tggcgctcat cagtgtttct cctttcgccc gccagagtaa aaagcaaccg
    51421 tttacgttaa tgaaactgtc taaacacatg ctcgtggagt gccagttttt gcgaggaagg
    51481 ggagttagag acaggaattg cggaggcaat cacataatcg tggttaaacc acgaaaatga
    51541 gaagagaacc tgacaatgaa attatctgta attttctcat attgatattt cattaatcat
    51601 tctggcatgt cgcactctcg catttaatcg tttttatctg gatagcgctc ttttggtcgg
    51661 caatgttgaa ataatgaaag cggcatagat tgaggggcaa taatttgaac tcagtcgcaa
    51721 aattataatt aaaacggtca tgctacctaa tatatgcccg tttattgcat cgcgaaattt
    51781 gagaagacat aactcattaa atgaaaggga tgcaaatgaa taagtttatc gctgctgaag
    51841 ctgcggaatg tataggctgt catgcttgtg aaattgcctg tgcggtggca cacaatcaag
    51901 aaaactggcc gctgagtcac agtgacttta gaccgcgtat ccacgttgta gggaaaggcc
    51961 aggctgcgaa tccggtggcc tgccatcact gcaacaatgc cccttgcgtt acggcttgtc
    52021 cggttaatgc tctgactttc cagtccgata gcgtacaact ggacgagcaa aaatgtattg
    52081 gttgtaaaag atgcgcaatc gcttgcccct ttggcgtcgt tgagatggtc gatacgattg
    52141 cgcagaaatg cgacctttgt aaccagcgca gttctggcac gcaagcctgt attgaagtct
    52201 gcccaacaca ggcgttacga ctgatggacg ataaagggtt acagcagata aaggtggccc
    52261 gccagcgcaa aacggcagca ggaaaagcgt catcagtcgc tcagccatct cgcagtgcag
    52321 cgttgctccc cgttaactcg cgtaaaggcg cagataaaat ttcagcgagt gaacggaaaa
    52381 cccactttgg cgaaatctat tgcgggctgg atccactgca agcgacttat gagagtgacc
    52441 gctgtgttta ttgtgccgaa aaagctaact gcaactggca ttgcccgctg cataacgcta
    52501 ttccggatta catccgtctg gtacaggaag gaaagattat tgaagcggca gaactttgcc
    52561 accagaccag ttccttacca gaaatctgcg gcagggtatg cccacaggac cgtctttgtg
    52621 aaggcgcatg tactttgaaa gatcactctg gcgcagtctc tatcggtaat ctggaacgct
    52681 acatcaccga taccgcgctg gcgatgggct ggcgtcccga tgtcagcaaa gttgttcccc
    52741 gtagcgaaaa agtggcggtg attggcgctg ggccagcagg gttagggtgt gctgatattc
    52801 tggcgcgcgc gggagttcag gttgatgtct ttgatcgcca tccagaaatt ggcggtatgc
    52861 tgacttttgg cattcctcct ttcaaactcg ataaaacggt attaagccag cggcgagaga
    52921 tattcaccgc aatgggaatc gactttcatc ttaactgtga aattggccgc gatattacct
    52981 ttagcgattt aacttctgaa tatgatgcag ttttcatcgg cgtggggact tacgggatga
    53041 tgcgagcaga tctgccgcat gaagatgcac ccggtgtcat tcaggctcta ccgttcctga
    53101 ctgcccatac ccgccagctc atgggattgc cggagtctga agagtatccg ctgacggacg
    53161 tggaaggtaa gcgagtcgtg gtattgggcg gtggcgatac gacaatggat tgtttgcgga
    53221 cttccattcg cctcaatgct gccagcgtga cctgcgcgta tcgtcgtgat gaagtcagta
    53281 tgccgggctc gcgcaaagag gtggttaatg cgtgcgagga aggtgtcgag tttcagttca
    53341 atgttcaacc gcaatatatc gcttgtgacg aagatgggcg tttaactgcg gtgggcctga
    53401 ttcgtaccgc catgggtgag ccggggccgg atggtcgccg tcgtcctcgt ccggtagcgg
    53461 gttcagagtt tgaattgccc gccgatgttc tgattatggc ctttggtttc caggcgcatg
    53521 ccatgccgtg gttgcagggc agcggaatta aactcgataa atggggcctg attcaaaccg
    53581 gtgacgtcgg gtatttacct acccagacgc atctgaaaaa agtctttgct ggtggggatg
    53641 cagttcatgg cgcggatctg gttgtcactg caatggccgc aggaaggcag gcggcgcgcg
    53701 atatgttaac tctgtttgat acgaaggcat cgtgatgaaa tcgttaatta tcgttaatcc
    53761 ggctgactgt attggctgcc gtacttgtga agtagcctgt gtggtcgctc acccttcaga
    53821 acaggagttg aatgccgatg tctttttacc ccggctgaag gtacagcgac tggacagcat
    53881 cagtgcgccg gtgatgtgcc atcagtgtga aaacgcccct tgtgttggcg cttgccccgt
    53941 gggggcgctg acgatgggcg agcaggtggt gcagaccaat tctgcccgtt gtattggctg
    54001 tcagagttgc gtcagtgcgt gcccgtttgg aatgatcacc attcagtcgt tgccggggga
    54061 tacccgacaa caaattgtga aatgcgatct ctgtgaacag cgggaagagg ggcctgcctg
    54121 cgttgaatct tgcccaacac aggcgctgca gttgcttact gaaagagaac tcaggcgagt
    54181 ccgccagcag cgtattgttg ccagcggtga gaatcctctg tgaaagaaat ctccgcgctg
    54241 aaaggcgcgg agaatctatt agattgccca accacccgcg taaaatgcga ccagtgcggc
    54301 agtaatgatc accgtaccaa tattcagctt ttgccattcg cgtgcaaaga cgcggcctac
    54361 gaccagtgtc acaaagccca gcataatacc ggtaacgata ttacaagtca gaacgatgaa
    54421 cacggcacac accaggccag ccatagcgtc aataaaatca ttgaaatcca gcttcgagac
    54481 gttacttaac atcagcaaac ctacgtacat cagagcgggt gcagtggcgt aaccagggat
    54541 caaaaatgac agcggtgata agaacagaat cagcaggaat aacgccccca ctacggttgc
    54601 ggttaaccct gttttacccc cggcggcggt tcctgccgct gattcgatat aaaccgctgc
    54661 gggcgctgcg cccaccaggc cggagaatat tgaacttact gagtcactgg tcagggcttt
    54721 gccgccgttg atgatctggt tgtctttatc caacaaattc gcctgaccgg cgacggcacg
    54781 gatggtgcca gtagcgtcga acactgcggt catcaccaat gccagtacac tcggaagtac
    54841 agttggctgg agtgcgccca taatatcgag gctgaaaatc agagacttac catcttcgcc
    54901 agtcaggctt ggcatcgcca ccagaccgtg gtatttcacc gctgggtcaa agattaagcc
    54961 gatgatcgaa attgcaataa tcaccaacaa gatcccgccg ggtacgcgac acttctccag
    55021 accgaagatg accgccagcc ccagcaagct catcatcacc gggaaggagg taaacgcacc
    55081 gagcgccact ggcaagcctt caatcgggtt tttgataacc atacccacac cgttagcagc
    55141 aatcagcagc agaaacagcc cgataccgat acctgtaccg tgagcgatac ccatcggtaa
    55201 attacgtaag atccaggtac gcacaccggt tacggaaata gcggtgaaga tgacgcccat
    55261 cagaaagacc gcgcccagtg cgacaggaac gctaatttgt tgcccgagta ccagactgaa
    55321 tgcggtaaat gccgtcaagg aaatcacaca accaatcgcc attggcaaat tggcccacaa
    55381 ccccatcagc aacgagccga agcccgcgac cagacaggtg gcaacaaaca cagctgcggg
    55441 aggaaaacct gctttgccca gcattcccgg aacgacgata acggaataaa ccatggccag
    55501 aaaggtcgtt aagccagcca gtacttcctg acgaacggta ctgccacgag cggtaatttt
    55561 aaaataatta tccagcgcgc cctgtggctt tggtgcgtcc ggtgtttgta ggatgtctcc
    55621 agacataatg atgtcctcac gaggatgtta aagttttatt attagttgcg ttcgtacacc
    55681 agacgaccat caacgtaggt gcggtagatc gaacggtcat cgcccaacgt catcatcacg
    55741 aacaatttgt cgactaaaga aacagagttg tcatagcgca gctgctgtag cggagtggcg
    55801 gtgggttcca tcaccacgaa atcagcctct ttgccaggta aaaagttgcc aatcaaatcg
    55861 tcaaggccca gagatttcgc tccgccgagc gtggccaggt aaaacgcttc atatgccgag
    55921 aggcgatagc cttgtaattg caatactttg taggcttcgt tcagcgtttg cagcatgttg
    55981 aaagtggttc cggcaccgat atccgttccc atgcccactt taactttctt ctgccatgct
    56041 tttttcaagt tgaataagcc gctgccgagg taaaggttgg aggtcggaca gaaagcaatg
    56101 ctggatttgg tttcgctgag acgatcccac tctttttctt cgagatggac gcagtgagca
    56161 aagacacagt ttttaccggt caggccgtac tgatggtaaa catccagata accatcatgg
    56221 tcaggataaa gcgatttcac ccaggcaatt tcatctttgt tttcacagag atgggtatgt
    56281 acccacgtat ccggatattc ttctttcagg cgttgcgcca tcgccatctg ttcaggagat
    56341 gaggtcgggg cgaagcgtgg cgtaatcgca tatagcagac gaccattttt gtgccagcgt
    56401 tcaatcagtt ctttgctttg gtgatagctg ctttcggcag tgtcgagcag ataatccggt
    56461 gcgttgcggt ccatcatcac cttaccggca atcatacgca tattgatatg actggcggct
    56521 tcaaacagcg catcaacaga ttgcggatga acagtgccaa acaccagcgc cgtggtggtt
    56581 ccgttacgta aaagctgctt gatgaagaat gccgacattt cgcgggcgta ctctaaatcc
    56641 tcataacgac gttcagtagg gaaggtgtgt ttattcaacc actccagcaa ttgttcacca
    56701 taggccccca ccatttcact ttgcggataa tggatatgtg tatcgacaaa gcccggtact
    56761 atcagtttgc cgcgatagtc gcgcacgcga atagtgtcag gaatttgatg ctttccgtct
    56821 tcccattcgc caaaccattc cacttttccc tgtttaatga gtaataaacc atcctcaata
    56881 aaccgcagcg cagaggcaat ctcttccggg ttatcgaccg tacgggtgac atcaataaaa
    56941 ctgcctcgta ccgctttcaa cgtgtgttct cctgacatca ttgactcctt tactgttaat
    57001 ccatctcttc cgctgaggta ataccaggca gaacgttttc ctgtcggtag ccaccaggga
    57061 ggataatatt taataaaatc gcagttaacc cgccagcaca aatagggttt tcaactaata
    57121 cataaataga ggctggcaat attttaaaaa tttcgggatc gtaggagacg ccaag
//
LOCUS       DAPGUL010000019        49213 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.019, whole genome shotgun sequence.
ACCESSION   DAPGUL010000019 DAPGUL010000000
VERSION     DAPGUL010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 49213)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49213)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49213
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.019"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            100..3834
                     /gene="yfaL"
                     /locus_tag="RHX21_001275"
     CDS             100..3834
                     /gene="yfaL"
                     /locus_tag="RHX21_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIDA-I family autotransporter adhesin YfaL/EhaC"
                     /protein_id="HDV1986494.1"
                     /translation="MRIIFLRKEYLSLLPSMIASLFSANGVAAAIDLCQGYDIKASCH
                     ASRQSLSGITQDWSVADGQWLVFSDMTNNASGGAVFLQQGAEFSLLPENETGMTLFAN
                     NTVTGEYNNGGAIFAKENSTLNLTDVIFSGNVAGGYGGAIYSSGTNDTGAVDLRVTNA
                     MFRNNIANDGKGGAIYTINNDVYLSDVIFDNNQAYTSTSYSDGDGGAIDVTDNNSDSK
                     HPSGYTIINNTAFTNNTAEGYGGAIYTNSATAPYLIDISVDDSYSQNGGVLVDENNSA
                     AGYGDGPSTAAGGFMYLGLSEVTFDIADGKTLVIGNTENDGAVDSIAGTGLITKTGSG
                     DLVLNADNNDFTGEMQIENGEVTLGRSNSLMNVGDTHCQDDPQDCYGLTIGSIDQYQN
                     QAELNVGSTQQTFVHALTGFQNGTLNIDAGGNVTVNQGSFAGIIEGAGQLTIAQNGSY
                     VLAGAQSMALTGDIVVDDGAVLSLEGDAADLTALQDDPQSIVLNGGVLDLSDFSTWQS
                     GTSYNDGLEVSGSSGTVIGSQDVVDLAGGDNLHIGGDGKDGVYVVVDASDGQVSLANN
                     NSYLGTTQIASGTLMVSDNSQLGDTHYNRQVIFTDKQQESVMEITSDVDTRSDAAGHG
                     RDIEMRADGEVAVDAGVDTQWGALMADSSGQHQDEGSTLTKTGAGTLELTASGTTQSA
                     VRVEEGTLKGDVADILPYASSLWVGDGATFVTGADQDIQSIDAISSGTIDISDGTVLR
                     LTGQDTSVALNASLFNGDGTLVNATDGVTLTGELNTNLETDSLTYLSNVTVNGNLTNT
                     SGAVSLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSVSDQLVMNGNTAGNTTVVVN
                     SITGIGEPTSTGIKVVDFAADPTQFQNNAQFSLAGSGYVNMGAYDYTLVEDNNDWYLR
                     SQEVTPPSPPDPDPDPTPDPDPTPDPIPAYQPVLNAKVGGYRNNLRAANQAFMMERRD
                     HAGGNGQTLNLRVIGGRYHYTAAGQLAQHEDTSTVQLSGDLFSGRWGDDGEWMLGAVG
                     GYSDNQGESRSNMTGTRADNQNHGYAVGLTSSWYQHGNQKQGAWLDSWLQYAWFSNDV
                     SEQEDGTDHYHSSGIIASLEAGYQWLPGRGVVIEPQAQVIYQGVQQDDFTAANRARVS
                     QSQGDDIQTRLGLHSEWRTAVHVIPTLDLNYYHDPHSTEIEEDGSTISDDAVKQRGEI
                     KVGVTGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW"
     gene            complement(3962..4684)
                     /locus_tag="RHX21_001276"
     CDS             complement(3962..4684)
                     /locus_tag="RHX21_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-demethylubiquinone
                     3-O-methyltransferase/2-octaprenyl-6-hydroxy phenol
                     methylase"
                     /protein_id="HDV1986495.1"
                     /translation="MNAEKSPENHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLR
                     LGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESG
                     IQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTL
                     NRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNP
                     LTNTFKLGPGVDVNYMLHTQNK"
     gene            4831..7458
                     /gene="gyrA"
                     /locus_tag="RHX21_001277"
     CDS             4831..7458
                     /gene="gyrA"
                     /locus_tag="RHX21_001277"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit A"
                     /protein_id="HDV1986496.1"
                     /translation="MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPV
                     HRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYML
                     VDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP
                     TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFP
                     TAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEK
                     IAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINM
                     VALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDP
                     IIELIRHAPTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYL
                     TEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELEL
                     VREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKG
                     KSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLP
                     LEQDERITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDEL
                     IGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRG
                     DGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMI
                     TDAGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAA
                     EGDDEIAPEVDVDDEPEEE"
     gene            7607..9295
                     /locus_tag="RHX21_001278"
     CDS             7607..9295
                     /locus_tag="RHX21_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416733.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2138 domain-containing protein"
                     /protein_id="HDV1986497.1"
                     /translation="MSGEKKAKGWRFYGLVGFGAIALLSAGVWALQYAGSGPEKTLSP
                     LVVHNNLQIDLNEPDLFLDSDSLSQLPKDLLTIPFLHDVLSEDFVFYYQNHADRLGIE
                     GSIRRIVYEHDLTLKDKLFSSLLDQPAQAALWHDKQGHLSHYMVLIQRSGLSKLLEPL
                     LFAATSDSQLSKTEISSIKINSETVPVYQLRYNGNNALMFATYQNKMLVFSSTDMLFK
                     DDQQDTEATAIAGDLLSGKKRWQASFGLEERAAEKTPVRQRIVVSARLLGFGYQRLMP
                     SFAGVRFEMGNDGWHSFVALNDESASVDTSFDFTPVWNSMPAGASFCVVVPYSHGIAE
                     EMLSHISQENDKLNGALDGAAGLCWYADSKLQTPLFVGQFDGTAEQAQLPGKLFTQNI
                     GAHESKAPEGVLPISQTQQGEAQIWRREVSSRYGQYPKAQAAQPDQLMSDYFFRVSLA
                     MQNKTLLFSLDDTLVNNALQTLNKNRPAMVDVIPTDGIVPLYINPQGVAKLLRNETLT
                     SLPKNLEPVFYNAAQTLLMPKLDALSQQPRYVMKLAQMEPGAAWQWLPITWQPL"
     gene            9292..9915
                     /locus_tag="RHX21_001279"
     CDS             9292..9915
                     /locus_tag="RHX21_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311139.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1175 domain-containing protein"
                     /protein_id="HDV1986498.1"
                     /translation="MRHGLLALICWLCCVVAHSEMLNVEQSGLFRAWFVRIAQEQLRQ
                     GPSPRWYQQDCAGLVRFAANETLKVHDSKWLKSNGFSSQYLPPEMTLTPGQRQLAQNW
                     NQGNGKTGPYVTAINLIQYNSQFIGQDINQALPGDMIFFDQGDAQHLMVWMGRYVIYH
                     TGSATKTDNGMRAVSLQQLMTWKDTRWIPNDSNPNFIGIYRLNFLAR"
     gene            9939..14452
                     /locus_tag="RHX21_001280"
                     /pseudo
     CDS             9939..14452
                     /locus_tag="RHX21_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000536590.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-2-macroglobulin family protein"
     gene            14453..16102
                     /locus_tag="RHX21_001281"
     CDS             14453..16102
                     /locus_tag="RHX21_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfaQ family protein"
                     /protein_id="HDV1986499.1"
                     /translation="MNWRRIVWLLALVTLPTLAEETPLQLVLRGAQHDQLYQLSSSGV
                     TKVSALPDSLTTPLGSLWKLYVYAWLEDTHQPEQPYQCRGNSPEEVYCCQAGESITRD
                     TALVRSCGLYFAPQRLHIGADVWGQYWQQRQAPAWLASLTTLKPETSVTVKSLLDSLA
                     TLPAQNKAQEVLLDVVLDEAKIGVASMLGSRVRVKTWSWFADDKQEIRQGGFAGWLTD
                     GTPLWVTGSGTSKTVLTRYATVLNRVLPVPTQVASGQCVEVELFARYPLKKITAEKST
                     TAVKPGVLNGRYRVTFTNGNHITFVSHGETTLLSEKGKLKLQSHLDREEYVARVLDRE
                     AKSTPPEAAKAMTVAIRTFLQQNANREGDCLTIPDSSATQRVSASPATTGARTMAAWT
                     QDLIYAGDPVHYHGSRATEGTLSWRQATAQAGQGERYDQILAFAYPDNSLSRWGAPRS
                     TCQLLPKAKAWLAKKKPQWRRILQAETGYNEPDVFAVCRLVSGFPYTDRQQKRLFIRN
                     FFTLQDRLDLTHEYLHLAFDGYPTGLDENYIETLTRQLLMD"
     gene            16107..16883
                     /locus_tag="RHX21_001282"
     CDS             16107..16883
                     /locus_tag="RHX21_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfaP family protein"
                     /protein_id="HDV1986500.1"
                     /translation="MRKIFLPLLLVALSPVVHSEGVQEVEIDAPLSGWHPVEGEDASF
                     SQSINYPASSVNMADDQNISAQIRGKIKNYAAAGKVQQGRLVVNGASMPQRIESDGSF
                     ARPYIFTEGSNSVQVISPDGQSRQKMQFYSTPGTGTIRARLRLVLSWDTDNTDLDLHV
                     VTPDGEHAWYGNTVLKNSGALDMDVTTGYGPEIFAMPAPVHGRYQVYINYYGGRSETE
                     LTTAQLTLITDEGSVNEKQETFIVPMRNAGELTLVKSFDW"
     gene            17158..20007
                     /gene="rcsC"
                     /locus_tag="RHX21_001283"
     CDS             17158..20007
                     /gene="rcsC"
                     /locus_tag="RHX21_001283"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416722.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     RcsC"
                     /protein_id="HDV1986501.1"
                     /translation="MKYLASFRTTLKASRYMFRALALVLWLLIAFSSVFYIVNALHQR
                     ESEIRQEFNLSSDQAQRFIQRTSDVMKELKYIAENRLSAENGVLSPRGRETQADVPAF
                     EPLFADSDCSAMSNTWRGSLESLAWFMRYWRDNFSAAYDLNRVFLIGSDNLCMANFGL
                     RDMPVERDTALKALHERINKYRNAPQDDSGSNLYWISEGPRPGVGYFYALTPVYLANR
                     LQALLGVEQTIRMENFFLPGTLPMGVTILDENGHTLISLTGPESKIKGDPRWMQERSW
                     FGYTEGFRELVLKKNLPPSSLSIVYSVPVDKVLERIRMLILNAILLNVLAGAALFTLA
                     RMYERRIFIPAESDALRLEEHEQFNRKIVASAPVGICILRTADGVNILSNELAHTYLN
                     MLTHEDRQRLTQIICGQQVNFVDVLTSNNTNLQISFVHSRYRNENVAICVLVDVSSRV
                     KMEESLQEMAQAAEQASQSKSMFLATVSHELRTPLYGIIGNLDLLQTKELPKGVDRLV
                     TAMNNSSSLLLKIISDILDFSKIESEQLKIEPREFSPREVMNHITANYLPLVVRKQLG
                     LYCFIEPDVPVALNGDPMRLQQVISNLLSNAIKFTDTGCIVLHVRADGDYLSIRVRDT
                     GVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLISMMDGDISVDSEPGMGS
                     QFTVRIPLYGAQYPQKKGVEGLSGKRCWLAVRNASLCQFLETSLQRSGIVVTTYEGQE
                     PTPEDVLITDEVVSKKWQGRAVVTFCRRHIGIPLEKAPGEWVHSVAAPHELPALLARI
                     YLIEMESDDPANALPSTDKAVSDNDDMMILVVDDHPINRRLLADQLGSLGYQCKTAND
                     GVDALNVLSKNHIDIVLSDVNMPNMDGYRLTQRIRQLGLTLPVIGVTANALAEEKQRC
                     LESGMDSCLSKPVTLDVIKQTLTVYAERVRKSRES"
     gene            complement(20207..20857)
                     /gene="rcsB"
                     /locus_tag="RHX21_001284"
     CDS             complement(20207..20857)
                     /gene="rcsB"
                     /locus_tag="RHX21_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RcsB"
                     /protein_id="HDV1986502.1"
                     /translation="MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINN
                     LPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLD
                     IEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLR
                     LFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTLSPADKD"
     gene            complement(20874..23546)
                     /gene="rcsD"
                     /locus_tag="RHX21_001285"
     CDS             complement(20874..23546)
                     /gene="rcsD"
                     /locus_tag="RHX21_001285"
                     /EC_number="2.7.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase RcsD"
                     /protein_id="HDV1986503.1"
                     /translation="MRQKETTATTRFSLLPGSITRFFLLLIIVLLVTMGVMVQSAVNA
                     WLKDKSYQIVDITHAIQKRVDNWRYVTWQIYDNIAATTSPSSGEGLQETRLKQDVYYL
                     EKPRRKTEALIFGSHDNSTLEMTQRMSTYLDTLWGAENVPWSMYYLNGQDNSLVLIST
                     LPLKDLTSGFKESTVSDIVDSRRAEMLQQANALDERESFSNMRRLAWQNGHYFTLRTT
                     FNQPGHLATVVAFDLPINDLIPPGMPLDSFRLEPDTTATGDNDNEKEGTDSVSIHFNS
                     TKIEIASALNSTDMRLVWQVPYGTLLLDTLQNILLPLLLNIGLLALALFGYTTFRHFS
                     SRSTESLPSTAVNNELRILRAINEEIVSLLPLGLLVHDQESNRTVISNKIADHLLPHL
                     NLQNITTMAEQHQGIIQATINNELYEIRMFRSQVAPRTQIFIIRDQDREVLVNKKLKQ
                     AQRLYEKNQQGRMTFMKNIGDALKEPAQSLAESAAKLNAPESKQLANQADVLVRLVDE
                     IQLANMLADDSWKSETVLFSVQDLIDEVVPSVLPAIKRKGLQLLINNHLKAHDMRRGD
                     RDALRRILLLLMQYAVTSTQLGKITLEVDQDESSEDRLTFRILDTGEGVSIHEMDNLH
                     FPFINQTQNDRYGKADPLAFWLSDQLARKLGGHLNIKTRDGLGTRYSVHIKMLAADPE
                     VEEEEERLLDDVCVMVDVTSAEIRNIVTRQLENWGATCITPDERLISQDYDIFLTDNP
                     SNLTASGLLLSDDESGVREIGPGQLCVNFNMSNAMQEAVLQLIEVQLAQEEVTESPLG
                     GDENAQLHASGYYALFVDTVPDDVKRLYTEAATSDFAALAQTAHRLKGVFAMLNLVPG
                     KQLCETLEHLIREKDVPGIEKYISDIDSYVKSLL"
     gene            24285..25409
                     /gene="ompC"
                     /locus_tag="RHX21_001286"
     CDS             24285..25409
                     /gene="ompC"
                     /locus_tag="RHX21_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpC"
                     /protein_id="HDV1986504.1"
                     /translation="MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYF
                     SDNKSEDGDQTYVRLGFKGETQVTDQLTGYGQWEYQIQGNTSEDNKENSWTRVAFAGL
                     KFQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYGSDNFMQQRGNGYATYRNTDFFG
                     LVDGLNFAVQYQGKNGSVSGEGMTNNGRGALRQNGDGVGGSITYDYEGFGIGAAVSSS
                     KRTDDQNFGLNGYGERYLGNGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSLGW
                     ANKAQNFEAVAQYQFDFGLRPSVAYLQSKGKNLGVVAGRNYDDEDILKYVDVGATYYF
                     NKNMSTYVDYKINLLDDNQFTRDAGINTDNIVALGLVYQF"
     gene            25521..26576
                     /gene="apbE"
                     /locus_tag="RHX21_001287"
     CDS             25521..26576
                     /gene="apbE"
                     /locus_tag="RHX21_001287"
                     /EC_number="2.7.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase ApbE"
                     /protein_id="HDV1986505.1"
                     /translation="MEISFTRVALLAAALFFVGCDQKPQPAKTHATEVTVLEGKTMGT
                     FWRASIPGIDAKRSAELKEKIQTQLDADDQLLSTYKKDSALMRFNDSQSLSPWPVSEA
                     MAEIVTTSLRIGAKTDGAMDITVGPLVNLWGFGPEQQPVQIPSQEQIDAMKAKTGLQH
                     LTVINQSHQQYLQKDLPDLYIDLSTVGEGYAADHLARLMEQEGISRYLVSVGGALDSR
                     GMNGEGQPWRVAIQKPTDKENAVQAVVDINGHGISTSGSYRNYYELDGKRLSHVIDPQ
                     TGRPIEHNLVSVTVIAPTALEADAWDTGLMVLGPEKAKEVVRREGLAVYMITKEGDSF
                     KTWMSPQFKSFLISEKN"
     gene            26650..27714
                     /gene="ada"
                     /locus_tag="RHX21_001288"
     CDS             26650..27714
                     /gene="ada"
                     /locus_tag="RHX21_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-binding transcriptional
                     regulator/O6-methylguanine-DNA methyltransferase Ada"
                     /protein_id="HDV1986506.1"
                     /translation="MKKATCLTDDQRWQSVLARDPNADGEFVFAVRTTGIFCRPSCRA
                     RHALRENVSFYANASEALAAGFRPCKRCQPDKANAQQHRLDKITHACRLLEQETPVTL
                     EALADHVAMSPFHLHRLFKATTGMTPKAWQQAWRARRLRESLAKGESVTTSILNAGFP
                     DSSSYYRKADETLGMTAKQFRHGGENLAVRYALADCELGRCLVAESERGICAILLGDD
                     DATLISELQQMFPAADNAPADLMFQQHVREVIASLNQRDTPLTLPLDIRGTAFQQQVW
                     QALRTIPCGETVSYQQLANAIGKPKAVRAVASACAANKLAIIIPCHRVVRGDGTLSGY
                     RWGVSRKAQLLRREAENEER"
     gene            27714..28364
                     /gene="alkB"
                     /locus_tag="RHX21_001289"
     CDS             27714..28364
                     /gene="alkB"
                     /locus_tag="RHX21_001289"
                     /EC_number="1.14.11.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA oxidative demethylase AlkB"
                     /protein_id="HDV1986507.1"
                     /translation="MLDLFADAEPWQEPLAAGAVILHRFAFNAAEQLIRDINDVASQS
                     PFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHDLCQR
                     AATAAGYPDFQPDACLINRYAPGAKLSLHQDKDEPDLRAPIVSVSLGLPAIFQFGGLK
                     RNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKAGFHPLTGDCRYNLTFRQAGKKE"
     gene            28440..30083
                     /gene="yojI"
                     /locus_tag="RHX21_001290"
     CDS             28440..30083
                     /gene="yojI"
                     /locus_tag="RHX21_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin J25 efflux ABC transporter YojI"
                     /protein_id="HDV1986508.1"
                     /translation="MELLVLVWRQYRWPFISVMALSLASAALGIGLIAFINQRLIETA
                     DTSLLVLPEFLGLLLLLMAVTLGSQLALTTLGHHFVYRLRSEFIKRILDTHVERIEQL
                     GSASLLAGLTSDVRNITIAFVRLPELVQGIILTIGSAAYLWMLSGKMLLVTAIWMAIT
                     IWGGFVLVARVYKHMATLRETEDKLYTDFQTVLEGRKELTLNRERAEYVFNNLYIPDA
                     QEYRHHIIRADTFHLSAVNWSNIMMLGAIGLVFWMANSLGWADTNVAATYSLTLLFLR
                     TPLLSAVGALPTLLTAQVAFNKLNKFALAPFKAEFPRPQAFPNWQTLELRNVTFSYQD
                     NAFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVSGEQP
                     EDYRKLFSAVFTDVWLFDQLLGPEGKPANPQLVEKWLAQLKMAHKLELSNGRIVNLKL
                     SKGQKKRVALLLALAEERDIILLDEWAADQDPHFRREFYQVLLPLMQEMGKTIFAISH
                     DDHYFIHADRLLEMRNGQLSELTGEERDAASRDAVARTA"
     gene            30301..31947
                     /gene="mqo"
                     /locus_tag="RHX21_001291"
     CDS             30301..31947
                     /gene="mqo"
                     /locus_tag="RHX21_001291"
                     /EC_number="1.1.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase (quinone)"
                     /protein_id="HDV1986509.1"
                     /translation="MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSA
                     TLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAGTGHSALMELNYTPQNADGSISI
                     EKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAAL
                     QQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIAS
                     LQKKSNFSLQLSSEVRALKRNDDNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLL
                     QESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGAPPMSVPHIDTRVLD
                     GKRVVLFGPFATFSTKFLKNGSLWDLMSSTTTSNVMPMMHVGLDNFDLVKYLVSQVML
                     SEEDRFEALKEYYPQAKKEDWRLWQAGQRVQIIKRDAEKGGVLRLGTEVVSDQQGTIA
                     ALLGASPGASTAAPIMLDLLEKVFGDRVSSPQWQATLKAIVPSYGRKLNGDVAATERE
                     LQYTSEVLGLKYDKPQAADSTPKPQLKPQPVQKEVADIAL"
     gene            complement(32096..32584)
                     /gene="eco"
                     /locus_tag="RHX21_001292"
     CDS             complement(32096..32584)
                     /gene="eco"
                     /locus_tag="RHX21_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease inhibitor ecotin"
                     /protein_id="HDV1986510.1"
                     /translation="MKTILPAVLFAAFATTSAWAAESVQPLEKIAPYPQAEKGMKRQV
                     IQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLESKTLEGWGYDYYVFDKVSSPVS
                     TMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDNVDVKYRVWKAEEKIDNAV
                     VR"
     gene            complement(32719..32883)
                     /locus_tag="RHX21_001293"
     CDS             complement(32719..32883)
                     /locus_tag="RHX21_001293"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986511.1"
                     /translation="MHTPIGVKPVAGSKEWREAWQKRAFAHISNGYKHIYIAINSPEI
                     FLLVCSLIRI"
     gene            32992..33486
                     /gene="napF"
                     /locus_tag="RHX21_001294"
     CDS             32992..33486
                     /gene="napF"
                     /locus_tag="RHX21_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-type protein NapF"
                     /protein_id="HDV1986512.1"
                     /translation="MKIDASRRGILTGRWRKASNGIRPPWSGDESHFLTHCTRCDACI
                     NACENNILQRGAGGYPSVNFKNNECSFCYACAQACPESLFSPRHTRAWDLQFTIGDAC
                     LAYQSVECRRCQDSCEPMAIIFRPTLSGIYQPQLNSQLCNGCGACAASCPVSAITAEY
                     LHAH"
     gene            33476..33739
                     /gene="napD"
                     /locus_tag="RHX21_001295"
     CDS             33476..33739
                     /gene="napD"
                     /locus_tag="RHX21_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone NapD"
                     /protein_id="HDV1986513.1"
                     /translation="MHTNWQVCSLVVQAKSERISDISTQLNAFPGCEVAVSDAPSGQL
                     IVVVEAEDSETLIQTIESVRNVEGVLAVSLVYHQQEEQGEETP"
     gene            33736..36222
                     /gene="napA"
                     /locus_tag="RHX21_001296"
     CDS             33736..36222
                     /gene="napA"
                     /locus_tag="RHX21_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase catalytic subunit NapA"
                     /protein_id="HDV1986514.1"
                     /translation="MKLSRRSFMKANAVAAAAAAAGLSVPGVARAVVGQQEAIKWDKA
                     PCRFCGTGCGVLVGTQQGRVVACQGDPDAPVNRGLNCIKGYFLPKIMYGKDRLTQPLL
                     RMKNGKYDKEGEFTPITWDQAFDVMEEKFKTALKEKGPESIGMFGSGQWTIWEGYAAS
                     KLFKAGFRSNNIDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGANMAE
                     MHPILWSRITNRRLSNQNVTVAVLSTYQHRSFELADNGIIFTPQSDLVILNYIANYII
                     QNNAINQDFFSKHVNLRKGATDIGYGLRPTHPLEKAAKNPGSDASEPMSFEDYKAFVA
                     EYTLEKTAEMTGVPKDQLEQLAQLYADPNKKVISYWTMGFNQHTRGVWANNLVYNLHL
                     LTGKISQPGCGPFSLTGQPSACGTAREVGTFAHRLPADMVVTNEKHRDICEKKWNIPS
                     GTIPAKIGLHAVAQDRALKDGKLNVYWTMCTNNMQAGPNINEERMPGWRDPRNFIIVS
                     DPYPTVSALAADLILPTAMWVEKEGAYGNAERRTQFWRQQVQAPGEAKSDLWQLVQFS
                     RRFKTEEVWPEELLAKKPELRGKTLYEVLYATPEVSKYPVSELAEDQLNDESRELGFY
                     LQKGLFEEYAWFGRGHGHDLAPFDDYHKARGLRWPVVNGKETQWRYSEGNDPYVKAGE
                     GYKFYGKPDGKAVIFALPFEPAAEAPDEEYDLWLSTGRVLEHWHTGSMTRRVPELHRA
                     FPEAVLFIHPLDAKARDLRRGDKVKVVSRRGEVISIVETRGRNRPPQGLVYMPFFDAA
                     QLVNKLTLDATDPLSKETDFKKCAVKLEKV"
     gene            36229..36924
                     /gene="napG"
                     /locus_tag="RHX21_001297"
     CDS             36229..36924
                     /gene="napG"
                     /locus_tag="RHX21_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-type protein NapG"
                     /protein_id="HDV1986515.1"
                     /translation="MSRSAKPQNGRRRFLRDVVRTAGGLAAVGVALGLQQQTARASGV
                     RLRPPGAINENAFASACVRCGQCVQACPYDTLKLATLASGLSAGTPYFVARDIPCEMC
                     EDIPCAKVCPSGALDREIESIDDARMGLAVLVDQENCLNFQGLRCDVCYRECPKIDEA
                     ITLELERNTRTGKHARFLPTVHSDACTGCGKCEKVCVLEQPAIKVLPLSLAKGELGHH
                     YRFGWLEGNNGKS"
     gene            36911..37774
                     /gene="napH"
                     /locus_tag="RHX21_001298"
     CDS             36911..37774
                     /gene="napH"
                     /locus_tag="RHX21_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinol dehydrogenase ferredoxin subunit NapH"
                     /protein_id="HDV1986516.1"
                     /translation="MANRKRDAGREALEKKGWWRSHRWLVLRRLCQFFVLGMFLSGPW
                     FGVWILHGNYSSSLLFDTVPLTDPLMTLQSLASGHLPATVALTGAVIITVLYALAGKR
                     LFCSWVCPLNPITDLANWLRRRFDLNQSATIPRHIRYVLLVVILVGSALTGTLIWEWI
                     NPVSLMGRSLVMGFGSGALLILALFLFDLLVVEHGWCGHICPVGALYGVLGSKGVITV
                     AATDRQKCNRCMDCFHVCPEPHVLRAPVLDEQSPVQVTSRDCMTCGRCVDVCSEDVFT
                     ITTRWSSGAKS"
     gene            37771..38220
                     /gene="napB"
                     /locus_tag="RHX21_001299"
     CDS             37771..38220
                     /gene="napB"
                     /locus_tag="RHX21_001299"
                     /EC_number="1.9.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311119.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase cytochrome c-type subunit"
                     /protein_id="HDV1986517.1"
                     /translation="MKSHDLKKALCQWTAMLALVVSGAVWAANGVDFSQSPEVSGTQE
                     GAIRMPKEQERMPLNYVNQPPMIPHSVEGYQVTTNTNRCLQCHGVESYRTTGAPRISP
                     THFMDSDGKVGAEVAPRRYFCLQCHVPQADTAPIVGNTFTPSKGYGK"
     gene            38230..38832
                     /gene="napC"
                     /locus_tag="RHX21_001300"
     CDS             38230..38832
                     /gene="napC"
                     /locus_tag="RHX21_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type protein NapC"
                     /protein_id="HDV1986518.1"
                     /translation="MGNSDRKPGLIKRLWKWWRTPSRLALGTLLLIGFVGGIVFWGGF
                     NTGMEKANTEEFCISCHEMRNTVYQEYMDSVHYNNRSGVRATCPDCHVPHEFVPKMIR
                     KLKASKELYGKIFGVIDTPQKFEAHRLTMAQNEWRRMKDNNSQECRNCHNFEYMDTTA
                     QKSVAAKMHDQAVKDGQTCIDCHKGIAHKLPDMREVEPGF"
     gene            38851..39468
                     /gene="ccmA"
                     /locus_tag="RHX21_001301"
     CDS             38851..39468
                     /gene="ccmA"
                     /locus_tag="RHX21_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001300065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis heme-transporting ATPase
                     CcmA"
                     /protein_id="HDV1986519.1"
                     /translation="MLEARELLCERDERTLFSGLSFTLNAGEWVQITGSNGAGKTTLL
                     RLLTGLSRPDAGEVLWQGQPLHQVRDSYHQNLLWIGHQPGIKTRLTALENLHFYHRDG
                     DTAQCLEALAQAGLAGFEDIPVNQLSAGQQRRVALARLWLTRATLWILDEPFTAIDVN
                     GVDRLTQRMAQHTEQGGIVILTTHQPLNVAESKIRRISLTQTRAA"
     gene            39465..40127
                     /gene="ccmB"
                     /locus_tag="RHX21_001302"
     CDS             39465..40127
                     /gene="ccmB"
                     /locus_tag="RHX21_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmB"
                     /protein_id="HDV1986520.1"
                     /translation="MMFWRIFRLELRVAFRHSAEIANPLWFFLIVITLFPLSIGPEPQ
                     LLARIAPGIIWVAALLSSLLALERLFRDDLQDGSLEQLMLLPLPLPAVVLAKVMAHWM
                     VTGLPLLILSPLVAMLLGMDVYGWQVMALTLLLGTPTLGFLGAPGVALTVGLKRGGVL
                     LSILVLPLTIPLLIFATAAMDAASMHLPVDGYLAILGALLAGTATLSPFATAAALRIS
                     IQ"
     gene            40169..40906
                     /gene="ccmC"
                     /locus_tag="RHX21_001303"
     CDS             40169..40906
                     /gene="ccmC"
                     /locus_tag="RHX21_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmC"
                     /protein_id="HDV1986521.1"
                     /translation="MWKTLHQLAIPPRLYQICGWFIPWLAIASVVVLTVGWIWGFGFA
                     PADYQQGNSYRIIYLHVPAAIWSMGIYASMAVAAFIGLVWQMKMANLAVAAMAPIGAV
                     FTFIALVTGSAWGKPMWGTWWVWDARLTSELVLLFLYVGVIALWHAFDDRRLAGRAAG
                     ILVLIGVVNLPIIHYSVEWWNTLHQGSTRMQQSIDPAMRSPLRWSIFGFLLLSATLTL
                     MRMRNLILLMEKRRPWVSELILKRGRK"
     gene            40903..41112
                     /gene="ccmD"
                     /locus_tag="RHX21_001304"
     CDS             40903..41112
                     /gene="ccmD"
                     /locus_tag="RHX21_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmD"
                     /protein_id="HDV1986522.1"
                     /translation="MTPAFASWNEFFAMGGYAFFVWLAVVMTVIPLVVLVVHSVMQHR
                     AILRGVAQQRAREARLRAAQQQEAA"
     gene            41109..41588
                     /gene="ccmE"
                     /locus_tag="RHX21_001305"
     CDS             41109..41588
                     /gene="ccmE"
                     /locus_tag="RHX21_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c maturation protein CcmE"
                     /protein_id="HDV1986523.1"
                     /translation="MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEIL
                     YGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKVTFTIYDAEGSVDVSYEGILPDL
                     FREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS"
     gene            41585..43528
                     /gene="ccmF"
                     /locus_tag="RHX21_001306"
     CDS             41585..43528
                     /gene="ccmF"
                     /locus_tag="RHX21_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis heme lyase CcmF"
                     /protein_id="HDV1986524.1"
                     /translation="MMPEIGNGLLCLALGIALLLSVYPLWGVARGDARMMASSRLFAW
                     LLFMSVAGAFLVLVNAFVVNDFTVTYVASNSNTQLPVWYRVAATWGAHEGSLLLWVLL
                     MSGWTFAVAIFSQRIPLDIVARVLAIMGMVSVGFLLFILFTSNPFSRTLPNFPIEGRD
                     LNPLLQDPGLIFHPPLLYMGYVGFSVAFAFAIASLLCGRLDSTYARFTRPWTLAAWIF
                     LTLGIVLGSAWAYYELGWGGWWFWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWT
                     LLLAISAFSLCLLGTFLVRSGVLVSVHAFASDPARGMFILAFMVLVIGGSLLLFAARG
                     HKVRSRVNNALWSRESLLLANNVLLVAAMLVVLLGTLLPLVHKQLGLGSISIGEPFFN
                     TMFTWLMVPFALLLGVGPLVRWGRDRPRKIRNLLIIAFISTLVLSLLLPWLFESKVVA
                     MTVLGLAMACWIAVLAIAEAALRISRGTKTTFSYWGMVAAHLGLAVTIVGIAFSQNYS
                     VERDVRMKSGDSVDIHEYRFTFRDVKEVTGPNWRGGVATIGVTRDGKPETVLYAEKRY
                     YNTAGSMMTEAAIDGGITRDLYAALGEELENGAWAVRLYYKPFVRWIWAGGLMMALGG
                     LLCLFDPRYRKRVSPQKTAPEAV"
     gene            43525..44082
                     /gene="dsbE"
                     /locus_tag="RHX21_001307"
     CDS             43525..44082
                     /gene="dsbE"
                     /locus_tag="RHX21_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbE"
                     /protein_id="HDV1986525.1"
                     /translation="MKRKVLLIPLIIFLAIAAALLWQLARNAEGDDPTNLESALIGKP
                     VPKFRLESLDNPGQFYQADVLTQGKPVLLNVWATWCPTCRAEHQYLNQLSAQGIRVVG
                     MNYKDDRQKAISWLKELGNPYALSLFDGDGMLGLDLGVYGAPETFLIDGNGIIRYRHA
                     GDLNPRVWEEEIKPLWEKYSKEAAQ"
     gene            44079..45131
                     /gene="ccmH"
                     /locus_tag="RHX21_001308"
     CDS             44079..45131
                     /gene="ccmH"
                     /locus_tag="RHX21_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis thiol:disulfide
                     oxidoreductase CcmH"
                     /protein_id="HDV1986526.1"
                     /translation="MRFLLGVLMLMISGSALATIDVLQFKDEAQEQQFRQLTEELRCP
                     KCQNNSIADSNSMIATDLRQKVYELMQEGKSKKEIVDYMVARYGNFVTYDPPLTPLTV
                     LLWVLPVVAIGIGGWVIYARSRRRVRVVPEAFPEQSVQEGKRAGYIVYLPGIVVALIV
                     AGVSYYQTGNYQQVKIWQQATAQAPALLDRALDPKADPLNEEEMSRLALGMRTQLQKN
                     PGDIEGWIMLGRVGMALGNASIATDAYATAYRLDPKNSDAALGYAEALTRSSDPNDNR
                     LGGELLRQLVRTDHSNIRVLSMYAFNAFEQQRFGEAVAAWEMMLKLLPANDTRRAVIE
                     RSIAQAMQHLSLQESK"
     gene            complement(45166..45813)
                     /gene="narP"
                     /locus_tag="RHX21_001309"
     CDS             complement(45166..45813)
                     /gene="narP"
                     /locus_tag="RHX21_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite response regulator protein NarP"
                     /protein_id="HDV1986527.1"
                     /translation="MPEATPFQVMIVDDHPLMRRGVRQLLELDPGFEVVAEAGDGASA
                     IDLANRLDIDVILLDLNMKGMSGLDTLNALRRDGVTAQIIILTVSDASSDVFALIDAG
                     ADGYLLKDSDPEVLLEAIRAGAKGSKVFSERVNQYLREREMFGAEEDPFSVLTERELD
                     VLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATILFLQQRGAQ"
     gene            46133..48724
                     /gene="yejO"
                     /locus_tag="RHX21_001310"
                     /pseudo
     CDS             46133..48724
                     /gene="yejO"
                     /locus_tag="RHX21_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311108.2"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter YejO"
BASE COUNT        11644 a        12039 c        13654 g        11876 t
ORIGIN      
        1 gccattgcat cgggttggac aatttacaaa agaaagataa cccatattgt ataatgcgtt
       61 taaatatgcc gtcttatata aaatgatggt cagattaata tgcggattat ctttctacgc
      121 aaggagtatt tatctctact cccgtcaatg attgcatctc ttttctctgc taacggtgtc
      181 gcggcggcca ttgatttatg ccagggatat gatatcaaag cgagttgtca cgccagcagg
      241 caaagccttt caggcattac gcaggactgg agtgtcgccg atgggcaatg gctggttttt
      301 tcggatatga ccaataatgc cagcggagga gccgtatttt tgcaacaagg agcggaattt
      361 tcactattac cagaaaatga aactggaatg actctgtttg ccaataacac cgttacagga
      421 gaatataata acggcggggc catatttgct aaagaaaact caacgctgaa tcttactgat
      481 gttatttttt ccggtaacgt cgcaggcggc tatggtggcg caatctattc ttctggtact
      541 aacgatactg gtgccgtcga tttacgtgtc actaacgcca tgtttcgcaa taacatcgct
      601 aatgatggca aaggtggcgc aatttatacc attaataatg acgtttattt aagtgatgtt
      661 atttttgata acaaccaggc atatacatca acaagttaca gtgatggcga tggcggggca
      721 atcgatgtta ccgataataa tagcgacagc aagcatcctt caggttatac gataataaat
      781 aacaccgcct ttacaaataa cactgccgaa ggttatggcg gggcgatata taccaatagc
      841 gcgacggctc cctatcttat tgatatttct gttgatgaca gctacagcca gaacggcggc
      901 gtgttagtgg atgagaacaa cagcgcagca ggctatggag atggtccttc cactgcggcg
      961 ggtggcttta tgtatctcgg cttaagtgaa gttacctttg atattgccga cggaaaaacg
     1021 ctggttattg gcaatacaga gaatgacgga gctgttgact ctattgctgg taccgggttg
     1081 atcaccaaaa caggttccgg cgatctggta cttaatgcag ataacaatga ctttactggt
     1141 gagatgcaga ttgaaaacgg tgaagttacc ctgggccgca gcaactccct gatgaatgtc
     1201 ggcgatacgc attgccagga cgatccgcaa gactgctacg gtctgacgat agggagtatt
     1261 gatcagtatc agaatcaggc tgagctaaac gttggctcga cccaacaaac ttttgtgcac
     1321 gcattgacgg gctttcagaa tggcacttta aatatcgatg ctggtggcaa cgttactgtt
     1381 aatcagggca gttttgctgg catcatcgaa ggtgctggtc agctcaccat tgcgcaaaac
     1441 ggcagctacg tgctggcagg ggcgcagtcg atggcgctaa ccggcgatat agtcgttgat
     1501 gatggtgcgg tgctttcgct ggaaggcgac gcggcagatc ttaccgctct ccaggacgat
     1561 ccgcagtcga tcgtgttaaa cggcggtgtg ctcgatctct ctgatttctc cacctggcag
     1621 agcggcacat catacaacga tggccttgaa gtcagtggca gcagcggaac ggttatcggc
     1681 agtcaggatg tggtagatct tgcaggtggc gacaatttgc atatcggcgg cgacgggaaa
     1741 gatggcgtct acgtggtggt cgatgcgagc gacgggcagg taagtctggc aaacaataat
     1801 agttatttgg gcacaacaca aatcgcctcc ggtacgctga tggtgagcga caactcgcag
     1861 cttggagata cccactataa ccgccaggtt atctttaccg ataagcaaca agaaagcgtg
     1921 atggagatta cctccgacgt tgacacgcgt tcagatgcgg caggccacgg acgtgatatt
     1981 gaaatgcgcg ccgacggtga agtggcagtt gatgcggggg tagacacgca gtggggcgca
     2041 ctgatggctg acagcagcgg gcagcatcag gatgagggta gcacattgac taaaacgggg
     2101 gctggtacac tggagctgac cgccagcggt acaacgcagt cggcggtacg tgtcgaagaa
     2161 ggcaccctga aaggtgatgt tgctgatatc cttccttatg cttcgtcact gtgggttggt
     2221 gatggggcaa cgttcgttac tggcgcggat caggatattc agtcaattga tgctatttcc
     2281 agcggcacta tcgacatcag cgatggtacg gttttgcgcc tgaccgggca ggatacttcc
     2341 gtcgccctta atgcctcact atttaacggc gatgggacgc tggtgaatgc caccgatggt
     2401 gtgacgttga caggtgagct taataccaac cttgaaactg acagcctgac ttatctttcc
     2461 aacgtgacgg ttaatggcaa tctgaccaat acgtccggtg cggttagcct gcaaaatggc
     2521 gtcgctggcg atacgctgac ggtaaacggt gattataccg gcggcggtac gctactgctc
     2581 gatagcgaat taaacggcga tgactcggta agcgatcaat tggtgatgaa cggtaatact
     2641 gctggcaaca caactgtggt ggttaactcc attacaggga ttggtgagcc gacatcgaca
     2701 ggcattaaag tggttgattt cgcagctgat cccacgcagt ttcaaaacaa tgcgcagttc
     2761 agtctggcag gcagcggcta cgtcaatatg ggagcgtatg actacacgct ggtggaagat
     2821 aacaacgact ggtatctgcg atcgcaagaa gtaacgccgc catcgccacc tgatccagac
     2881 cctgacccaa cacccgatcc tgacccaaca cccgatccaa tccccgctta ccagccggtg
     2941 ctgaatgcca aagttggcgg ttatcgcaat aatctgcggg cggcaaatca ggcgtttatg
     3001 atggagcgac gcgatcatgc aggtggcaat ggtcagacgc tgaatttacg tgttatcggc
     3061 ggacgttatc attacacggc ggcagggcaa ctggctcagc atgaagacac ttctacggtg
     3121 cagcttagcg gtgacctgtt tagcgggcgc tggggcgatg atggcgagtg gatgcttggg
     3181 gcggttggtg gctacagtga taatcagggc gagagccgct cgaatatgac cggaactcgc
     3241 gccgataacc agaaccacgg ttatgccgtt gggctgacct caagctggta tcagcacggt
     3301 aatcagaagc agggggcctg gctggatagc tggctgcaat acgcgtggtt tagcaatgat
     3361 gtttccgaac aagaagatgg cacagatcat taccactcgt cggggattat cgcctcgctg
     3421 gaggcggggt atcagtggtt accggggcgt ggtgtggtga ttgaaccgca ggcgcaggtg
     3481 atttatcagg gcgtgcagca ggatgatttt accgccgcta accgtgcgcg cgtgtcacaa
     3541 tcgcagggtg atgatattca gacgcggctg ggtttacaca gcgaatggcg taccgctgtt
     3601 catgtcatac caacattaga tctgaattat tatcacgatc cccattcgac ggaaattgaa
     3661 gaggatggca gcactatcag tgacgatgcg gtgaagcaac ggggtgaaat aaaagtggga
     3721 gtcacgggca atatcagtca gcgagtgtcc ctgcgcggca gcgtggcgtg gcagaaaggg
     3781 agtgatgatt ttgcccagac ggcagggttt ttgtcgatga cggtgaaatg gtaatcactg
     3841 tctagtcggc acggttgccg gatgcggcgt aaacgcctta tccggcctac ggggagcatt
     3901 tgtaggcctg ataagacgcg gcaagcgtcg catcaggcat tggctcggcc aaacaacaac
     3961 ctcacttatt ctgcgtgtgc agcatatagt tcacatccac gccggggccg agtttaaaag
     4021 tattagtgag cgggttgtaa tgtagcccgg ttatatgtcg ctctttaagg cttgtctgat
     4081 ctacccagcc aagcagttct gccggtttaa taaacttctt cacatcatgc gtgcctttgg
     4141 gcaccatgcg caaaatatat tccgcgccaa ccaccgccat cagccatgac ttgccgttgc
     4201 ggttaagcgt cgagaaaaag acatcgccgc ctggtttcac cagttgcgca caggctctga
     4261 ccactgactg cggatcgggg acgtgctcca gcatctccat gcaggtcacc acatcatact
     4321 gcccggcatg ttttgccgcg tgctcttcca cggtttcctg cacataatcc acctgaatgc
     4381 cgctttccag cgcgtgcagt tttgccacct gcaatggctc aaagcccata tccagaccgg
     4441 tcaccgtcgc gccttcgcgc gccatactct cggccagaat gccgccgcca caaccgacat
     4501 cgagcacctt tttgccaaat aaaccgccag cacgctcggc aatatagccc agacgcagcg
     4561 ggttaatgcg gtgcaacggt ttgaactcac cttcaagatc ccaccagcgg gaggcgacgg
     4621 cttcaaattt agcgatctct tcgtggtcta cgttatggtt ttccggcgat ttttcggcat
     4681 tcattggcac ttctactccg taattggcaa gacaaacgag tatatcaggc attggatgtg
     4741 aataaagcgt ataggtttac ctcaaactgc gcggctgtgt tataatttgc gacctttgaa
     4801 tccgggatac agtagaggga tagcggttag atgagcgacc ttgcgagaga aattacaccg
     4861 gtcaacattg aggaagagct gaagagctcc tatctggatt atgcgatgtc ggtcattgtt
     4921 ggccgtgcgc tgccagatgt ccgagatggc ctgaagccgg tacaccgtcg cgtactttac
     4981 gccatgaacg tactaggcaa tgactggaac aaagcctata aaaaatctgc ccgtgtcgtt
     5041 ggtgacgtaa tcggtaaata ccatccccat ggtgactcgg cggtttatga cacgatcgtc
     5101 cgtatggcgc agccattctc gctgcgttac atgctggtag acggtcaggg taacttcggt
     5161 tccatcgacg gcgactctgc ggcggcaatg cgttatacgg aaatccgtct ggcgaaaatt
     5221 gcccatgaac tgatggccga tctcgaaaaa gagacggtcg atttcgttga taactatgac
     5281 ggcacggaaa aaattcccga cgtcatgcca accaaaattc ctaacctgct ggtgaacggt
     5341 tcttccggta tcgccgtagg tatggcaacc aacatcccgc cgcacaacct gacggaagtc
     5401 atcaacggtt gtctggcgta tatcgatgat gaagacatca gcattgaagg gctgatggaa
     5461 cacatcccgg ggccggactt cccgacggcg gcaatcatta acggtcgtcg cggtattgaa
     5521 gaagcttacc gtaccggtcg cggcaaggtg tatatccgcg ctcgcgcaga agtggaagtt
     5581 gacgccaaaa ccggtcgtga aaccattatc gtccacgaaa ttccgtatca ggtaaacaaa
     5641 gcgcgcctga tcgagaagat tgcggaactg gtaaaagaaa aacgcgtgga aggcatcagc
     5701 gcgctgcgtg acgagtctga caaagacggt atgcgcatcg tgattgaagt gaaacgcgat
     5761 gcggtcggtg aagttgtgct caacaacctc tactcccaga cccagttgca ggtttctttc
     5821 ggtatcaaca tggtggcatt gcaccatggt cagccgaaga tcatgaactt gaaagacatc
     5881 atcgcggcgt ttgttcgtca ccgccgtgaa gtggtgaccc gtcgtactat tttcgaactg
     5941 cgtaaagctc gcgatcgtgc tcatatcctt gaagcattag ccgtggcgct ggcgaacatc
     6001 gacccgatca tcgaactgat ccgtcatgcg ccgacgcctg cagaagcgaa aactgcgctg
     6061 gttgctaatc cgtggcagct gggcaacgtt gccgcgatgc tcgaacgtgc tggcgacgat
     6121 gctgcgcgtc cggaatggct ggagccagag ttcggcgtgc gtgatggtct gtactacctg
     6181 accgaacagc aagctcaggc gattctggat ctgcgtttgc agaaactgac cggccttgag
     6241 cacgaaaaac tgctcgacga atacaaagag ctgctggatc agatcgcgga actgttgcgt
     6301 attcttggta gcgccgatcg tttgatggaa gtgatccgtg aagagctgga gctggttcgt
     6361 gaacagttcg gtgacaaacg tcgtactgaa atcaccgcca acagcgcaga cattaacctg
     6421 gaagatctga tcactcagga agatgtggta gtgacgctct ctcaccaggg ctacgttaag
     6481 tatcagccgc tttctgaata cgaagcgcag cgtcgtggcg ggaaaggtaa atctgccgca
     6541 cgtattaaag aagaagactt tatcgaccga ctgctggtgg cgaacactca cgaccatatt
     6601 ctgtgcttct ccagccgtgg tcgcgtctat tcgatgaaag tttatcagtt gccggaagcc
     6661 actcgtggcg cgcgcggtcg tccgatcgtc aacctgctgc cgctggagca ggacgaacgt
     6721 atcactgcga tcctgccagt gaccgagttt gaagaaggcg tgaaagtctt catggcgacc
     6781 gctaacggta ccgtgaagaa aactgtcctc accgagttca accgtctgcg taccgccggt
     6841 aaagtggcga tcaaactggt tgacggcgat gagctgatcg gcgttgacct gaccagcggc
     6901 gaagacgaag taatgctgtt ctccgctgaa ggtaaagtgg tgcgctttaa agagtcttct
     6961 gtccgtgcga tgggctgcaa caccaccggt gttcgcggta ttcgcttagg tgaaggcgat
     7021 aaagtcgtct ctctgatcgt gcctcgtggc gatggcgcaa tcctcaccgc aacgcaaaac
     7081 ggttacggta aacgtaccgc agtggcggaa tacccaacca agtcgcgtgc gacgaaaggg
     7141 gttatctcca ttaaggttac tgaacgtaat ggtttagtgg ttggcgcggt acaggtagat
     7201 gactgcgacc agatcatgat gatcaccgat gccggtacgc tggtacgtac tcgcgtttcg
     7261 gaaatcagca tcgtaggccg taacacccag ggcgtgatcc tcatccgtac tgcggaagat
     7321 gaaaacgtag tgggtctgca acgtgttgct gaaccggttg acgaggaaga tctggatacc
     7381 atcgatggca gtgccgcgga aggggacgat gaaatcgctc cggaagtgga cgttgacgac
     7441 gagccagaag aagaataatt ttacttcttc atgccaaaag ggagctatct cccttgtttg
     7501 aattgaaaag tccaggctgc aaagtctggg cttttgtcgt attagggcac ggtaaagttt
     7561 ggctgtgccc gtaaaaaatg gctggctata cacaaggaat gtggcaatga gtggtgaaaa
     7621 aaaggcgaaa ggctggcggt tctatggtct tgtaggtttt ggcgcaatag cactgctttc
     7681 cgctggcgtc tgggcgttgc aatatgctgg cagtgggcca gaaaaaacgt tgtcgccgct
     7741 ggtggtgcac aacaatctgc aaatcgatct caatgagccg gacctctttc tcgacagcga
     7801 ctctctgagc cagcttccca aagatctcct caccattccg tttctccacg atgttctgag
     7861 cgaagatttc gttttctatt atcagaatca tgccgatcgt ctgggcattg aaggcagcat
     7921 tcgtcgtatt gtctatgaac acgatctcac gctgaaagat aagctctttt cgtcactctt
     7981 agatcagccc gcgcaggcag cgctgtggca cgataaacaa ggccatcttt cacattatat
     8041 ggtgctgatc cagcgcagtg gtttaagcaa actgctggag ccattgttgt ttgccgctac
     8101 cagcgacagc cagttaagca aaacggaaat cagtagcatc aagataaata gtgaaactgt
     8161 tcctgtttat cagttgcgct ataacggcaa taacgccctg atgttcgcga cttatcagaa
     8221 caagatgctg gtgttttcca gcacggatat gttgtttaaa gatgatcagc aggataccga
     8281 agccacggcg atcgcaggtg atttgttgag cggcaaaaaa cgctggcaag caagctttgg
     8341 cctggaagag cgtgctgctg aaaaaacgcc agtacgccag cgcatcgtgg tcagcgccag
     8401 gttgctgggt tttggctacc agcggttaat gccttctttt gctggcgtac gcttcgaaat
     8461 gggtaacgac ggctggcaca gttttgtggc gttaaatgat gaatccgcca gcgtagatac
     8521 cagtttcgat tttacgccgg tctggaacag tatgcctgcc ggggccagct tctgtgtggt
     8581 ggtgccgtat tcacacggta ttgccgaaga gatgctttcg cacatcagtc aggaaaacga
     8641 caagttgaat ggggcgttag acggtgccgc ggggctgtgc tggtatgcag actcaaaatt
     8701 gcaaaccccg ctgtttgtcg gtcagtttga tggcactgcc gaacaggcgc aattgccagg
     8761 gaaactgttt acgcaaaata ttggtgcgca cgaaagcaaa gcgccagaag gtgttttgcc
     8821 gataagccag actcagcagg gcgaagcgca aatctggcgt cgcgaagtga gttcccgata
     8881 cggtcagtat ccgaaagcgc aggcggcgca acccgatcaa ttaatgtcgg attatttttt
     8941 ccgcgtgtcg ctggcgatgc aaaacaaaac gctgcttttc tccctcgatg acacgctggt
     9001 taataacgcc ctgcaaacac tgaataaaaa ccgcccggca atggtggatg taatacccac
     9061 tgatggcatc gttccgctct atatcaatcc acaaggcgtg gcgaaactgc tgcgtaacga
     9121 aacgttgacc agtctgccga agaatctcga accggttttt tataacgccg cacaaacttt
     9181 attaatgccg aagctggacg ctttatctca acaaccgcgt tatgtcatga agctggccca
     9241 gatggaaccc ggtgccgcct ggcagtggct acccataacc tggcagccgc tatgaggcac
     9301 gggctgctgg cgctgatttg ctggctgtgt tgtgttgttg cccatagcga aatgctgaat
     9361 gtcgaacaat ccgggctgtt tcgcgcctgg tttgtacgca ttgcacaaga acagctccgc
     9421 caggggccaa gtccacgctg gtatcagcag gattgtgcgg gcctggtgcg atttgcggcg
     9481 aacgagacgc tgaaagttca cgatagtaaa tggctaaaaa gtaacggttt ctctagccag
     9541 tatttgccgc cagagatgac gctaacacct ggacagcgtc aactggcgca aaactggaat
     9601 caggggaacg ggaaaaccgg cccctacgtg accgcgatta atttgattca gtacaacagc
     9661 cagtttattg gccaggacat aaaccaggcg ctgcctggcg atatgatttt tttcgatcag
     9721 ggcgatgccc agcacttaat ggtctggatg gggcgttacg tcatctacca caccggaagc
     9781 gccacgaaaa ctgacaacgg aatgcgcgca gtcagtctgc aacaacttat gacatggaag
     9841 gacacccgat ggatacccaa cgattccaat cccaatttca ttggcattta tcgtttaaat
     9901 tttctggcgc gatagcagcg tgcttgtccc tgtctcttgt gggaacaggg cttgctaatg
     9961 ctgatgattc gcttccttcc agtaactatg cgccgcccgc cgggggaaca ttctttttgc
    10021 ttgctgacag cagttttagc agcagtgaag aggcgaaagt gcgactggaa gcgcccgggc
    10081 gtgattatcg gcgctatcag atggaagagt acggcggcgt ggacgttcgc ctgtatcgta
    10141 ttcctgaccc gatggcattt ttgcgccagc agaaaaacct gcatcgcatt gtggtgcaac
    10201 cgcaatatct gggcgacggg ctgaacaata cgctgacctg gctgtgggat aactggtacg
    10261 gcaaatctcg ccgcgtaatg cagcgtactt tctcttctca gtcacggcag aatgtgactc
    10321 aggcattacc cgaattacat ctcggcaatg ccattattaa accttcccgt tatgtacaga
    10381 acaaccagtt ttccccgctg aaaaaatatc ccttggtgga acagttccgt tatccactat
    10441 ggcaggctaa accggtcgag ccgcagcaag gggtaaaact ggaaggcgca tccagcaatt
    10501 tcatctcgcc gcagccgggt aacatttata ttcctctcgg ccaacaagag ccgggactgt
    10561 acctcgtcga ggcgatggtt ggtgggtatc gggcgacgac ggtggtgttt gtttccgata
    10621 ccgtggcgct tagcaaagtg tcaggcaacg agcttctggt gtggaccgcg ggtaaaaaac
    10681 agggtgaagc gaagcccggc tcagagatct tgtggactga cggtcttggc gtgatgaccc
    10741 gcggtgtgac cgatgacagc ggtaccttgc agttacaaca tatatcgcca gaacgttcat
    10801 acattctggg taaggatgct gaaggcggtg tttttgtctc cgagaacttc ttctacgaaa
    10861 gcgaaatcta caacacccgc ttgtatattt ttaccgatcg cccgctatat cgcgcaggcg
    10921 atcgtgtcga tgttaaagtg atgggccgcg agttccacga tccgttgcat tcatccccca
    10981 tcgtcagcgc cccggcgaag ctttcggtgc tggacgctaa cggcagtctg ttgcaaaccg
    11041 tcgatgtcac gctggatgcg cgcaatggcg ggcagggaag tttccgcctg ccagaaaatg
    11101 ccgttgccgg aggttatgag ttacgtcttg cttaccgcaa tcaggtctat agcagcagtt
    11161 ttcgcgtggc aaactacatc aagccacatt tcgagattgg tttagctctc gacaaaaaag
    11221 agttcaaaac tggcgaagcg gtcagcggca aactgcaact gctctacccg gatggcgagc
    11281 cggtaaaaaa tgcccgcgtg cagttaagtt tgcgcgctca gcaattatca atggtcggta
    11341 acgatttgcg ttatgccgga cgtttccccg tgtcgctgga aggcagcgaa acggtgtccg
    11401 acgccagcgg tcatgtggcg ttaaatctcc ccgccgccga taaaccgagc cgttatttgt
    11461 taaccgtctc cgccagtgac ggcgcggcgt atcgtgtcac caccaccaaa gagatcctca
    11521 ttgaacgcgg tctggcgcat tactcattaa gtactgccgc acaatacagt aatagcggcg
    11581 agtcggttgt gttccgttat gccgcgctgg aatcttcaaa acaggttcct gttacgtatg
    11641 aatggttgcg tctcgaagac cgcacgagcc atagcggaga gctaccgtca ggcggcaaat
    11701 cctttaccgt caatttcgct aaacctggca actacaatct gacattacgc gataaagacg
    11761 gcttaattct cgctgggtta agttatgccg tcagcggtaa gggcagcacg gcgcatacgg
    11821 gtacggtaga tatcgtggcg gataaaacgc tgtaccagcc aggcgaaacc gcgaagatgc
    11881 tgattacctt tccggagcca attgatgaag cattattgac gctggaacgc gatcgcgtgg
    11941 aacagcagtc gctgctttcg catccggcaa actggctaac gctacaacgt ttaaacgata
    12001 cccagtatga agcccgggtt ccagtgagca attcctttgc gcctaacatc actttttcgg
    12061 tgctgtatac ccgtaatggt cagtacagtt ttcagaacgc cgggatcaaa gttgccgttc
    12121 ctcagcttga tatccgggtg aaaacggaca aaacccatta ccagcctggt gaactggtca
    12181 atgtcgaatt aacctcgtcg ctgaaaggta aacctgtttc tgcgcagcta acggtaggcg
    12241 tggtcgatga aatgatctac gcgctgcaac cagaaatcgc gccgaatatc ggcaaatttt
    12301 tctatccgct ggggcgtaac aatgtgcgta ccagctccag tctgtcgttt atcagctacg
    12361 accaggcgct ctccagcgag ccggttgcgc ctggcgcaac taaccgcagc gagcggcgag
    12421 taaaaatgct tgaacgtcca cggcgtgaag aggtggatac cgcggcatgg atgccgtcac
    12481 tcacaaccga taaacaaggc aaagcgtatt tcacgttcct gatgcctgat tcgttaaccc
    12541 gctggcgtat caccgcgcgt gggatgaacg gcgacgggct ggtcgggcag gggcgtgctt
    12601 atctgcgttc ggaaaaaaat ctctacatga agtggagtat gccaacggtg tatcgcgtgg
    12661 gcgacaaacc ggcggcagga ctgtttatct tcagtcagca ggataacgaa ccggtggcgc
    12721 tggtgactaa atttgcaggc gctgagatgc gccagacgct gacgctgcac aaaggggcga
    12781 attatatttc gctggcgcag aacattcagc aatctggctt gttaagcgca gaactgcaac
    12841 aaaatgggca agtgcaggac agcattagca caaaactgtc ttttgtggat aacagctggc
    12901 ccgttgaaca gcagaaaaat gtcatgctcg gcggtggcga gaacgcgctg atgttgcccg
    12961 agcaggctag caatatccgg ctacaaagta gcgaaacgcc gcaggagatt ttccgcaaca
    13021 atcttgatgc gttagtcgat ggaccatggg gtggcgtgat caacaccggt agccgtctga
    13081 tcccgctcag tctcgcctgg cgttcgcttg ccgatcatca aagtgccgcc gctaacgaca
    13141 ttcgtcagat gattcaggat aaccgtctgc ggctgatgca actggcgggg cccggagcgc
    13201 gctttacctg gtggggtgaa gatggcaatg gtgacgcctt ccttacggca tgggcatggt
    13261 acgccgactg gcaggccagc caggcgctcg gcgtaacgca acaaccggaa tactggcagc
    13321 atatgctcga cagttatgcc gagcaggcgg ataacatgcc gttattgcat cgggcgctgg
    13381 tgctggcgtg ggcacaggag atgaatctgc cgtgcaaaac gttgttgaaa gggttggatg
    13441 aagctatcgc ccggcgcgga actaaagatg aagatttctc tgaggaagac atccgcgata
    13501 tcaatgacag cctgatcctc gatacaccgg aatctccact ggcagatgcg gtggcaaacg
    13561 tcttaaccat gacgttgctg aaaaaagcgc agttgaagtc cacggtgatg ccacaggttc
    13621 agcaatatgc gtgggataaa gcggcaaaca gcaatcagcc gctggcgcac acggttgtgc
    13681 tgctcaatag cggtggtgac gctacccaga cggccgctat tttagtggtt tgaccgctga
    13741 gcaatccact attgagcgcg cgctggccat gaactggctg gcgaaatata tggcgacaat
    13801 gcctccagtt gttttgcctg cgcctgcggg cgcatgggct aaacataagt taactggagg
    13861 gggcgaagac tggcgttggg ttgggcaggg tgtgccggac attctctctt ttggtgacga
    13921 attatcgccg caaaatgtgc aggtccgctg gcgtgaaccg gcaaaaacgg ctcaacaaag
    13981 taacattccg gtgaccgttg aacgccagtt gtatcggctt atccccggtg aagaagagat
    14041 gagctttact ctgcagccgg tgaccagcaa tgagattgac agcgatgcgc tgtatctcga
    14101 tgaaattacg cttaccagcg agcaggatgc agttctgcgc tatggtcagg tggaagtacc
    14161 gctcccgccg ggagccgacg ttgagcgcac aacatggggc atttcagtca ataaacccaa
    14221 cgccgcgaaa cagcaggggc aattgctgga aaaagcgcgt aatgaaatgg gcgaactggc
    14281 ctatatggtg ccggtgaaag aactgacggg aacggtcact ttccgccatt tgctgcgctt
    14341 ctcgcaaaaa gggcaattcg ttctgcctcc tgctcgttat gtgcgttcct atgcacctgc
    14401 gcagcaaagt gttgcggcag ggagtgaatg gaccgggatg caggtgaaat aagtgaactg
    14461 gcgcagaatc gtctggctat tggcgttggt tactctgcca acgcttgcgg aggagacgcc
    14521 gttacaactg gtgctgcgcg gtgcgcagca cgatcaactg tatcagctgt cgtcatcagg
    14581 cgtgaccaaa gtctcagcat tacctgactc gctcaccacg ccgttaggga gtttgtggaa
    14641 actgtatgtt tacgcctggc tggaggatac ccatcaaccg gagcagccct accagtgtcg
    14701 cggaaactcc ccggaagagg tttattgttg tcaggctggg gagagcataa cgcgcgatac
    14761 cgcgctggta cgttcctgtg ggctctattt tgcgccgcag cggttgcata ttggcgcaga
    14821 tgtgtggggg caatactggc aacagcgtca ggcacctgcg tggttagcgt ctcttacaac
    14881 gctgaagcca gaaacctcgg taacggttaa atcgctgctc gattcattag cgacgttacc
    14941 tgcgcaaaac aaagctcagg aagtcttact ggatgtggtg ctggacgagg cgaaaatcgg
    15001 tgtcgcatcc atgctcggta gtcgggtacg ggtgaaaacc tggagctggt ttgccgatga
    15061 taaacaggaa atccgccagg gtggttttgc tggctggtta accgatggta caccgctgtg
    15121 ggttactggc agtggcacca gcaaaacggt actaacccgt tatgcgacgg tgcttaatcg
    15181 ggttttgcca gtgccgacgc aggttgccag tgggcaatgt gtagaggtgg agctgtttgc
    15241 ccgctatccg ctgaagaaaa tcacagcgga aaagagtacg acggcagtaa aacccggcgt
    15301 acttaatggg cgctatcgtg tgacgtttac taatggtaac cacattacgt ttgtcagcca
    15361 cggtgagacg accttactga gcgaaaaggg caaactgaaa ttgcagtcac atctcgatcg
    15421 tgaagagtac gttgccagag ttctggatcg cgaggcgaaa agtacgcccc ctgaggcagc
    15481 gaaagccatg accgtggcga ttcgcacttt tttacagcaa aacgccaatc gggaaggcga
    15541 ttgcctgacc atccctgaca gcagcgccac gcagcgtgtt tcggcttcgc cagctacgac
    15601 gggggcgcga acgatggccg cctggacgca ggatctcatc tatgcgggcg atccggttca
    15661 ttatcatggc agtcgcgcta ccgaagggac gctttcctgg cggcaagcca cggcccaggc
    15721 ggggcaggga gagcgttacg accagatact cgcgtttgct tatcccgaca acagccttag
    15781 ccgctgggga gcgccacgct caacctgcca gttattaccc aaagcgaaag cctggctggc
    15841 gaaaaaaaag ccgcagtggc ggcgtatatt acaagctgag acggggtaca acgaaccaga
    15901 cgtgtttgcg gtttgccgtt tagtctcagg tttcccctat accgatcggc agcagaaacg
    15961 gctgtttatt cgtaacttct ttacgcttca ggatcggctg gatttaaccc atgagtatct
    16021 gcacctggcc tttgatggtt atcccaccgg gcttgatgag aactatatcg aaacgctgac
    16081 ccgacaatta ttaatggact aatgctatgc gaaagatttt tcttccgttg ttactggtgg
    16141 cactttcgcc tgtcgttcac agtgaaggtg tgcaggaagt cgagattgac gcaccgctct
    16201 ctggctggca tccggtagag ggcgaagatg ccagtttttc acaatcgatc aattacccgg
    16261 cgtcgtccgt caacatggca gatgatcaaa atatctcagc gcagatccgc ggcaaaataa
    16321 agaattatgc tgcggcgggt aaagttcagc agggccggct ggtggtcaac ggtgccagta
    16381 tgccgcagag aattgaatcc gatggttcat ttgcacgccc ttatattttc actgaaggca
    16441 gcaacagcgt gcaggtcatc agcccggatg ggcaaagccg acaaaaaatg cagttttact
    16501 caacgccggg tacaggaacg attcgtgcac gtttacggct ggttctctcg tgggatacgg
    16561 acaataccga tctcgatctc catgttgtca cgcccgatgg cgaacacgcc tggtacggta
    16621 acaccgtgct gaaaaacagt ggtgcactgg atatggatgt cacgacgggg tacggacccg
    16681 agattttcgc catgccagca ccagttcacg ggcgctatca ggtgtatatc aactactatg
    16741 gtgggcgcag cgaaacggaa ttgacgaccg cccaactgac gctgatcacc gatgaaggat
    16801 cggtcaatga gaaacaggaa acatttattg taccgatgcg taatgctggc gagctgacgc
    16861 tggtgaaaag ttttgactgg tgatccatcc cttcacacaa cctggctctc tcttttttca
    16921 gataagactg ctgggcgatc tgccgacgcc aggatataat cattaacaag cgtcggcaga
    16981 ttggtcattt cttatttttc gtactgagaa ctgtccatct actccggctt tcctggttaa
    17041 ggcaatggtt tctaagcgat acgcattatt gcaatggtga cagaacattg cggtaacacg
    17101 cttttaccgc taccttaacc acactccatc ggtcacctga ggcggagctt cgcccctttg
    17161 aaataccttg cttcttttcg tacaaccctg aaagcctcgc gctacatgtt cagagcattg
    17221 gcgttagtgc tctggctgtt gattgctttt tcatccgttt tttacatcgt taatgcgtta
    17281 catcagcgag aatcggaaat tcgtcaggaa tttaatctga gttccgatca ggctcagcgc
    17341 tttattcaac gcacctctga tgtgatgaaa gagctgaagt acatcgccga aaatcgctta
    17401 tcggcagaaa acggtgtgct ttccccgcgt ggacgagaaa cgcaggcgga tgtgcctgcg
    17461 tttgaaccgc tgtttgccga ctccgattgt tccgcaatga gtaacacctg gcgaggttct
    17521 ctggagtcat tggcgtggtt tatgcgctac tggcgcgata atttttctgc ggcttacgat
    17581 ctcaaccggg tatttttaat cggcagtgat aacctctgca tggccaattt cggtctgcgt
    17641 gatatgccag tggaacgcga taccgcgttg aaagctttgc atgaacgcat caataaatat
    17701 cgaaatgcac cacaagatga tagcggcagt aacctctact ggatcagcga aggtccgcgc
    17761 cctggcgtcg ggtattttta cgcgttgacg ccagtttatc tggcgaaccg gttgcaggcg
    17821 cttttgggtg tcgagcagac catccggatg gagaactttt tcttaccggg tacgttgccg
    17881 atgggggtta ccattcttga tgaaaatggt cataccctga tttcgcttac cggaccagaa
    17941 agtaaaatta agggcgatcc tcgctggatg caggaacgct cctggtttgg ctatacggaa
    18001 gggttccggg agctggtgct gaagaaaaat ctgccaccct catcgctaag catcgtgtat
    18061 tcggtgccgg ttgataaggt gctggaacgc attcgcatgt tgatccttaa cgcaattttg
    18121 ctgaatgtgc ttgccggagc tgcattgttt actctcgcgc ggatgtacga gcgacgtatt
    18181 ttcattccgg cggaaagcga cgccctgcga ctggaagaac atgagcagtt caatcgcaag
    18241 attgtcgcct ccgcgccagt gggtatctgc attttgcgta ccgctgatgg cgtcaatatt
    18301 ttaagtaacg aactggcgca tacctatctc aatatgctta cgcatgagga ccgccaacga
    18361 ctgacgcaaa ttatctgtgg gcagcaggtc aattttgttg atgtcctgac cagcaacaat
    18421 accaatctgc aaatcagctt cgtccattcg cgctatcgta atgaaaacgt ggccatttgt
    18481 gtgctggtgg atgtttcttc gcgcgtgaag atggaagagt cgttgcagga gatggcacaa
    18541 gcagcggaac aggcgagcca gtcaaaatcg atgttccttg ccaccgtcag tcatgagctg
    18601 cgaacgccgc tgtatggcat tatcggtaac ctggatctgt tgcaaaccaa agagttaccg
    18661 aaaggcgtcg atcggctggt gacggcaatg aacaactctt ccagcctgtt gttgaaaatt
    18721 atcagcgata ttctcgattt ctcgaagatt gaatcggaac agttgaagat cgaaccgcgt
    18781 gagttttcac cgcgtgaagt gatgaaccac atcaccgcca actatttacc gctggtggta
    18841 cgcaagcagt taggcttgta ctgctttatt gaaccggatg tgccagtggc cttaaatggc
    18901 gacccgatgc gtttacagca ggtcatctcc aacctgttga gtaacgccat aaaattcacc
    18961 gataccggct gtatagtttt gcatgtccgc gctgatggcg attatctctc tatccgtgtt
    19021 cgcgataccg gcgtggggat tccggcgaaa gaagtggtgc gcttgtttga tcccttcttc
    19081 caggtcggaa cgggcgtaca gcgaaacttc caggggaccg gtctgggtct ggcgatttgt
    19141 gaaaaactga tcagcatgat ggacggcgat atctcggtag attcagaacc gggaatgggc
    19201 agccagttta ccgtgcgtat tccgttgtac ggcgctcagt acccgcagaa aaaaggcgtg
    19261 gaagggttga gtggtaaacg ctgctggctg gcggtccgca atgcgtcgct ctgtcagttc
    19321 ctggaaacca gtttgcagcg cagcggcatc gtcgttacaa catacgaagg gcaggaaccg
    19381 actcccgaag atgtgttaat tactgacgag gtagtgagta aaaaatggca gggtagagcg
    19441 gtagtgacct tctgtcgtcg ccatattggt attccgctgg agaaagcgcc aggggagtgg
    19501 gtacacagtg tggctgcccc gcatgagcta ccggcattgt tggcgcgtat ttatttgatc
    19561 gagatggaga gcgacgatcc tgctaacgct ctgccgtcga cggacaaagc ggtcagcgat
    19621 aatgacgata tgatgattct ggtcgtggat gatcatccga ttaaccgacg tctgctggca
    19681 gatcagttgg gatcgttggg ctatcaatgt aaaaccgcga atgatggtgt cgatgcgctt
    19741 aatgtactta gcaagaatca tattgatatc gtgcttagcg acgtcaacat gccaaatatg
    19801 gatggttacc gcttgacgca acgcattcgt cagttgggac tgacgttgcc ggtaatcgga
    19861 gtaactgcta atgcgttggc tgaagagaag cagcggtgtc tggagtccgg tatggacagc
    19921 tgcctgtcga agccggtaac gctggatgtg ataaaacaga cgctgacggt atatgccgag
    19981 agggtcagga aatcgcggga atcgtaggac ggataaggtg tttatgccgc atctggcatt
    20041 cagtgcaaat gccagatgcg acgctgacgc gtcttatctg gcctacttta atgtaatctg
    20101 ttgaaataat gggaatcgta ggccggataa ggcgtttacg ctgcatccgg caatcggtgc
    20161 aaatgccaga taagacacta acgcgtctta tctggcctac agatgattag tctttatctg
    20221 ccggacttaa ggtcacagaa gagagataat tcagcagggc gatatcgttc tcgacaccca
    20281 gcttcatcat cgcagatttc ttctggctac tgatggtttt aatactgcgg ttcagctttt
    20341 tagcgatctc ggtcaccagg aagccttccg caaacaggcg cagaacttca ctctcttttg
    20401 gcgagagacg cttgtcaccg taaccaccag cactgatttt ttccaacagg cgagaaacgc
    20461 tttccggggt aaatttcttc cctttctgca gcgcggcgag agctttcggc agatcggtcg
    20521 gtgcaccttg tttcagcacg atcccttcga tatccagatc caataccgca ctaagaatcg
    20581 ccgggttgtt gttcatggtc agaacaatga tcgacaggct tgggaaatgg cgcttgatgt
    20641 acttgattaa ggtaatgcca tcgccgtact tatcgccagg catggagaga tcggtaatca
    20701 acacatgcgc atccagtttc ggcaggttgt tgatcagtgc tgtagagtct tcaaattcgc
    20761 cgacaacatt cacccactca atttgctcaa gtgatttgcg aataccgaac aagactatcg
    20821 gatggtcatc ggcaataatt acgttcatat tgttcatgta ataggctacc ttgctacagc
    20881 aagctcttga cataactgtc aatgtcgctg atgtattttt ctattcctgg aacatccttc
    20941 tcacgaatca gatgttccag cgtttcacat aactgcttgc cgggtaccag atttagcatg
    21001 gcaaatacgc ctttaagacg atgagccgtt tgggctaacg cagcaaagtc actggttgct
    21061 gcttcagtat acagcctctt aacatcatcc ggtactgtgt ctacaaagag cgcataatag
    21121 ccgctggcat ggagttgcgc attttcatct ccgcccagag gcgattctgt cacctcttcc
    21181 tgcgccagtt gcacttcaat taattgtaag accgcttcct gcatagcgtt gctcatattg
    21241 aagttgacgc acaattgacc aggcccaatt tcccgtacgc cagactcatc atcgcttaaa
    21301 agcaagccag aggcagtaag attagacgga ttatccgtta aaaagatatc ataatcttga
    21361 ctaattaatc tttcatcggg tgtgatacag gttgcacccc aattttctaa ctggcgagtg
    21421 acaatattcc gaatttctgc cgaagtaaca tccaccatta cgcagacatc atccagtaaa
    21481 cgctcttctt cctcttcaac ttccgggtca gctgcgagca ttttgatatg cacagagtag
    21541 cgtgtaccaa gcccatcccg cgttttgatg tttaaatgac cgcccagttt acgtgccagt
    21601 tgatcgctca gccagaatgc cagcgggtcc gccttgccat agcgatcgtt ttgggtctgg
    21661 ttgataaacg ggaagtgcaa attatccatt tcatgaatac ttacgccttc tcccgtgtcc
    21721 agaatgcgga acgtcaggcg gtcttcggag gactcatcct gatcaacctc aagggtgatt
    21781 tttcccaatt gcgttgaggt cacggcatat tgcatcagta gcagcaaaat acgtcgtaag
    21841 gcatcgcgat cgccgcggcg catatcgtgt gctttcagat gattgttaat cagcagttgc
    21901 agacctttac gcttgatggc aggcaacact gaaggcacaa cttcatcaat taaatcctgc
    21961 acggagaaca gcaccgtctc acttttccag ctatcatccg caagcatgtt cgctaactgt
    22021 atttcatcaa ccagccgcac cagcacatct gcctgattcg ccagttgttt gctttccggg
    22081 gcgttgagtt tagccgcgct ctccgccagg gactgtgcgg gttctttcag cgcatcgcca
    22141 atgtttttca taaaggtcat ccgcccctgc tggtttttct catacagacg ctgcgcctgc
    22201 ttgagtttct tgtttaccag cacttcgcga tcctgatcgc gaataatgaa aatttgtgtg
    22261 cgcggcgcga cctggctgcg gaacatgcgg atctcataca gctcgttatt gatcgtcgcc
    22321 tgaataatcc cctgatgctg ttccgccatg gtggtgatgt tttgcagatt caaatgcggc
    22381 agcaaatgat cggcaatttt gttacttatg acagtgcggt tcgattcctg atcgtgaacc
    22441 agcaggccga gcggcagcag tgagactatc tcttcattaa ttgcccgtaa aatgcgcaat
    22501 tcgttattga ccgccgtgct gggtagactt tctgtactgc ggctggagaa atggcggaat
    22561 gtggtatagc caaataacgc cagcgccagc aaaccgatgt tcagcagcag tggcagcaga
    22621 atgttttgca acgtatccag caataaggtg ccataaggaa cctgccagac caggcgcata
    22681 tcggtagagt tgagtgccga ggcgatttca atcttcgtac tgttaaagtg gatactgacg
    22741 ctatccgttc cttctttctc attatcattg tctcccgttg ccgtcgtgtc tggctcaagg
    22801 cggaaactgt ccagcggcat acccggtggg atcaaatcat taatcggcag atcaaaagcc
    22861 acgaccgttg ccagatgtcc tggctggtta aaggtagtac gcaatgtaaa gtaatgaccg
    22921 ttctgccagg ccaggcggcg catgttagaa aagctttcgc gttcatcgag ggcgttggcc
    22981 tgttgcaaca tctctgcacg acgtgaatca acaatgtcgc tgacggtcga ttctttaaat
    23041 ccggaggtga gatctttaag gggtagggtt gagatcagca ccagactgtt atcctgacca
    23101 ttcaggtaat acatcgacca cggtacattt tctgcgcccc acaatgtatc cagataagtg
    23161 gacatccgct gagtcatctc aagcgttgag ttgtcgtgag agccaaagat taacgcttcc
    23221 gttttgcggc gtggtttctc cagatagtag acatcctgtt tcaggcgcgt ctcttgtaaa
    23281 ccttcgccgg aggaggggga ggtcgtcgcg gcaatgttgt cgtagatctg ccaggtcacg
    23341 taacgccagt tatcgacgcg cttttggata gcatgggtaa tgtcgacaat ctggtaactt
    23401 ttatctttca gccaggcgtt aacggcgctt tgtaccatta cacccatcgt caccagtaac
    23461 acaatgatca acagtaaaaa gaagcgggta atgctccccg gtaggagtga aaagcgggtc
    23521 gtggccgttg tctctttctg acgcattcgt gtttatgacc tgttaaaact tcgcgaagtg
    23581 atagggcagt ataaagggta cagtgtgaaa ttccagactc ttacctgatt gatgattctc
    23641 tattctcccg tgatatttat catcctgcat tgggggaaat agatgtacaa gcgccatttt
    23701 gctgtacaaa taacctacaa aaagcccaac aaaaataatt gcaaataaac aaagattgct
    23761 ggaaattatg cggatgttaa ttatttgtga aatagttaac aagcgttata gtttttctgt
    23821 ggtagcacag aataatgaaa agtgtgtaaa gaagggtaaa aaaaaccgaa tgcgaggcat
    23881 ccggttgaaa taggggtaaa cagacattca gaaatgaatg acggtaataa ataaagttaa
    23941 tgatgatagc gggagttatt ctagttgcga gtgaaggttt tgttttgaca ttcagtgctg
    24001 tcaaatactt aagaataagt tattgatttt aaccttgaat tattattgct tgatgttagg
    24061 tgcttatttc gccattccgc aataatctta aaaagttccc ttgcatttac attttgaaac
    24121 atctatagcg ataaatgaaa catcttaaaa gttttagtat catattcgtg ttggattatt
    24181 ctgcattttt ggggagaatg gacttgccga ctgattaatg agggttaatc agtatgcagt
    24241 ggcataaaaa agcaaataaa ggcatataac agagggttaa taacatgaaa gttaaagtac
    24301 tgtccctcct ggtcccagct ctgctggtag caggcgcagc aaacgctgct gaagtttaca
    24361 acaaagacgg caacaaatta gatctgtacg gtaaagtaga cggcctgcac tatttctctg
    24421 acaacaagtc agaagacggc gaccagacct atgtacgtct tggtttcaaa ggcgaaactc
    24481 aggttactga ccagctgacc ggttacggcc agtgggaata tcagatccag ggcaatacct
    24541 ctgaagacaa caaagaaaac tcctggaccc gtgtggcatt cgcaggtctg aaattccagg
    24601 atgttggttc tttcgactac ggtcgtaact acggcgttgt ttacgacgta acttcctgga
    24661 ccgacgtact gccagaattc ggtggcgaca cttacggctc tgacaacttc atgcagcagc
    24721 gtggtaatgg ctacgcaacc taccgtaaca ccgacttctt cggtctggtt gacggtctga
    24781 actttgctgt tcagtaccag ggcaaaaatg gtagcgtaag cggcgaaggc atgaccaaca
    24841 atggtcgtgg tgctctgcgt cagaatggcg acggtgtcgg cggatctatc acttatgatt
    24901 acgaaggctt cggtatcggt gctgcagttt ccagctccaa acgtactgat gatcagaact
    24961 tcggcctgaa cggttatggt gagcgttatt tgggtaacgg cgaccgcgct gaaacctaca
    25021 ctggtggtct gaaatacgac gctaacaaca tctacctggc tgctcagtac acccagacct
    25081 acaacgcaac tcgcgtaggt tccctgggtt gggcgaacaa agcacagaac ttcgaagctg
    25141 ttgctcagta ccagttcgac ttcggtctgc gtccatctgt agcatacctg cagtctaaag
    25201 gtaaaaacct gggtgtcgtt gctggtcgta actacgacga cgaagatatc ctgaaatatg
    25261 ttgatgttgg tgcgacctac tacttcaaca aaaacatgtc cacctacgtt gactacaaaa
    25321 tcaacctgct ggacgacaac cagttcactc gtgacgctgg catcaacact gataacatcg
    25381 tagctctggg tctggtttac cagttctaat ctcgattgat atcgaacaaa gggcctgcgg
    25441 gccctttttt cattgttttc agcgtacaaa ctcatttttt tggtgtactc ttgcgaccgt
    25501 tcgcatgagg ataatcacgt atggaaataa gctttacccg cgtggcactg ctggctgccg
    25561 cgctcttctt tgttggttgc gatcaaaaac cacaacccgc caaaacccac gctactgaag
    25621 ttaccgttct tgaaggcaaa accatgggta ccttctggcg tgccagcatc ccgggcattg
    25681 atgccaaacg cagtgccgaa cttaaagaaa agattcagac ccagctggac gccgacgatc
    25741 agctgctttc gacctataaa aaagattccg cgctgatgcg ctttaacgac tcgcaaagtt
    25801 tgtcgccgtg gccagtaagt gaagcgatgg ccgaaatcgt cactacctcg ctgcgcattg
    25861 gcgcgaagac cgatggtgcg atggatatta ccgtcgggcc gctggtgaat ctgtggggct
    25921 ttggcccgga acaacagccg gttcaaattc cgagccagga acagatcgat gcgatgaaag
    25981 ccaaaaccgg cttacagcac ctgacggtca tcaatcagtc gcatcagcaa tatctgcaaa
    26041 aagacctgcc ggatttatat atcgatctct ccaccgtcgg tgaaggttat gcggcggatc
    26101 acctggcacg cttgatggag caggaaggta tttcacgtta tctggtgtca gttggtggtg
    26161 ctctggatag ccgtggtatg aacggtgaag gccagccgtg gcgggtagcg attcaaaaac
    26221 caaccgataa agaaaacgcg gttcaggccg tggtggatat caacggtcat ggcattagca
    26281 cctctggcag ctaccgtaac tattacgaac tggacggcaa acgtctttct catgttatcg
    26341 atccgcaaac cgggcgtcct atcgaacaca atctggtatc cgtgacggtg attgccccga
    26401 cggcgctgga agccgatgcc tgggatactg gcttaatggt actcgggccg gagaaagcca
    26461 aagaggttgt tcgccgggaa gggctggcgg tctatatgat caccaaagaa ggtgatagct
    26521 ttaaaacctg gatgtcgccg cagtttaaaa gcttccttat cagcgaaaaa aattaaagcg
    26581 caagattgtt ggtttttgcg tgatggtgac cgggcagact aaaggctatc cttaaccagg
    26641 gagctgatta tgaaaaaagc cacatgctta actgacgatc aacgctggca atctgtctta
    26701 gcccgcgacc cgaatgccga cggcgaattc gttttcgccg tgcgtaccac aggcatcttt
    26761 tgccgtccgt cttgccgcgc cagacatgct ttgcgggaaa acgtctcctt ctacgcaaat
    26821 gccagcgagg cactcgccgc tggctttcgc ccctgcaaac gttgtcagcc agacaaagcc
    26881 aatgcccagc aacatcggtt ggataaaatt acccacgcct gtcgactgct ggaacaggaa
    26941 acgcctgtaa cgctggaagc cttagccgac catgtggcga tgagtccgtt ccatctgcat
    27001 cggttgttta aagcgactac cggaatgacg cctaaagcct ggcaacaggc ctggcgcgct
    27061 cgccgtttgc gcgaatcgct ggcgaaaggg gagagcgtga cgacgtctat tcttaacgcc
    27121 ggattccccg acagcagcag ttactaccgc aaagccgacg aaacgctggg catgacggct
    27181 aaacaattcc gtcacggtgg cgaaaatctg gcggtgcgtt acgcgctggc tgattgtgag
    27241 ctgggtcgtt gcctggtggc agaaagcgag cgggggattt gcgcgatatt gctgggcgat
    27301 gatgacgcga cactaatcag cgagttgcag cagatgtttc ccgctgccga caacgcgcct
    27361 gccgatctga tgtttcagca acatgtgcgt gaagtgatcg ccagcctcaa tcaacgcgat
    27421 acgccgctga cgttaccgct ggacattcgc ggcactgctt ttcagcaaca agtctggcag
    27481 gcactgcgca cgataccttg cggtgaaacc gtcagttatc agcaactggc taacgccatc
    27541 ggcaaaccga aagcggtacg ggccgttgcc agcgcctgtg ccgccaacaa gctggctatc
    27601 ataataccct gtcatcgggt ggtccgtggt gatggcacac tttccggtta ccgctggggc
    27661 gtgtcgcgta aagcgcaact gctgcgccgc gaagctgaaa atgaggagag gtaatgttgg
    27721 atctgtttgc cgatgctgaa ccgtggcaag agccactggc ggctggagcg gtaattttgc
    27781 accgttttgc ttttaacgct gcggagcaac tgatccgcga tattaatgac gttgccagcc
    27841 agtcgccgtt tcgccagatg gtcacccccg ggggatatac catgtcggtg gcgatgacca
    27901 actgtgggca tctgggctgg acgacccatc ggcaaggtta tctctattcg cccattgatc
    27961 cgcaaacaaa taaaccgtgg cccgccatgc cacaaagctt tcatgattta tgtcaacgtg
    28021 cggctacggc ggcgggctat ccggatttcc agccagatgc ttgtcttatc aaccgctacg
    28081 ctcctggcgc gaaactgtcg ctgcatcagg ataaagacga accggatctg cgcgcgccga
    28141 ttgtttctgt ttctcttggc ttacccgcga tttttcaatt tggtggcctg aaacgtaatg
    28201 atccgctcaa acgtttgttg ttggaacatg gcgatgtggt ggtatggggc ggtgaatcgc
    28261 ggctgtttta tcacggcatt caaccgctga aagcggggtt tcatccactc accggcgact
    28321 gccgctacaa cctgacattc cgtcaggcag gtaaaaaaga ataaaaataa gaattattat
    28381 tgctgtgcgc gcgaagatgt ttaaactgcg ggctgtaatt cattgtccgg gttttctgca
    28441 tggaacttct tgtacttgtc tggcggcagt atcgctggcc atttatcagt gtgatggcgc
    28501 taagcctcgc cagtgcggca ttaggcattg gcttaattgc ttttatcaat cagcgcctta
    28561 tcgaaacggc ggataccagt ctgctggtat tgccggagtt tctgggatta ttgctgctgt
    28621 tgatggcagt cactctcgga tcgcaactgg cgctcaccac tttggggcat cacttcgttt
    28681 accgactgcg tagtgaattt atcaagcgga ttctggatac ccacgtcgag cgcattgaac
    28741 aactcggtag cgcctcgttg ctggcgggat taaccagcga tgtgcgcaat atcaccattg
    28801 cttttgtgcg tcttccggaa ctggtgcagg ggatcattct cactatcggt tccgcggcgt
    28861 atctgtggat gctgtcgggc aaaatgttgc tggtaacggc tatctggatg gcgatcacca
    28921 tctggggtgg ttttgtactg gtggcgcggg tgtacaaaca tatggcgacc ctgcgtgaaa
    28981 ccgaagacaa gctgtacacg gattttcaaa ccgtactcga agggcgcaaa gagctgactc
    29041 tgaaccggga acgcgccgag tatgtgttta acaacctcta catccccgat gcgcaagagt
    29101 atcgccatca tattattcgc gcagacacct tccatcttag cgccgtgaac tggtcaaaca
    29161 tcatgatgct gggcgctatc ggcctggtgt tctggatggc gaacagtctc ggttgggctg
    29221 ataccaacgt tgctgcgacc tattcgttga cgctgttatt cctgcgtacg ccgctgcttt
    29281 cggcggttgg cgcattgccg acgctgctga cggcgcaggt ggcgtttaac aagctgaaca
    29341 aattcgcgct cgcgcctttc aaagctgagt ttccgcgccc gcaggctttt cccaactggc
    29401 aaacgctgga gctgcgtaac gtgacgttta gctatcagga taacgcgttt tccgttgggc
    29461 cgattaacct caccattaaa cgtggcgagc tgctgtttct gattggcggc aacggtagcg
    29521 gaaaatcgac gctggcgatg ttgttgacgg gcttgtatca gccacaaagc ggcgaaatct
    29581 tgctggatgg caaacctgtc agcggcgaac aaccggaaga ttatcgcaaa ctgttttcgg
    29641 cagtgtttac cgatgtctgg ctgtttgatc aactgctggg gccggagggt aaacccgcta
    29701 acccgcaact ggttgagaag tggctggcgc agctgaaaat ggctcataag cttgagttaa
    29761 gcaacgggcg tattgttaac ctgaagttat caaaagggca gaaaaaacgc gtggcgctgt
    29821 tgctggcgct ggcagaagaa cgcgatatta tcctgctgga tgaatgggcg gcggatcagg
    29881 atccacactt ccgtcgtgag ttttatcagg tgttgctgcc gctgatgcag gagatgggta
    29941 aaactatttt cgctatcagt catgatgatc attactttat ccacgccgac cgcctgctgg
    30001 aaatgcgcaa tgggcaactt agcgagctga cgggcgaaga gcgcgatgcc gcttcgcgtg
    30061 atgccgttgc ccggacggca taatattacg acgctgacct ggcggactgc tgccgtcagg
    30121 tcaatatgct aaaaatccct tcatttctaa taaccctata attaatcaac gaaattataa
    30181 tgtttctaaa attagaatat aatttataaa cattatttaa atgttgttac ttaagtgtta
    30241 ccgttgatgc cgcgcaaatc tcacctgcaa taaagcgact aaaagtaagg cattaacaag
    30301 atgaaaaaag tgactgccat gctcttctcg atggccgtgg ggcttaatgc cgtttcgatg
    30361 gcggcaaaag cgaaagcgtc cgaggagcag gaaactgatg tactgttgat tggcggcggc
    30421 attatgagcg ccacgttggg gacctattta cgcgagctgg agcctgaatg gtcgatgacc
    30481 atggtggagc gcctggaggg tgtcgcgcag gagagttcga acggctggaa taacgccgga
    30541 accgggcatt ctgcactgat ggaactgaac tacaccccgc aaaacgccga tggcagcatc
    30601 agtattgaaa aagcagtcgc cattaacgaa gcatttcaga tttcccgcca gttctgggcg
    30661 caccaggttg agcgcggcgt gctgcgtact ccgcgttcat ttatcaatac cgttccgcat
    30721 atgagctttg tctggggcga ggataacgtt aatttcctgc gcgcccgtta cgccgcgttg
    30781 caacaaagct cgctgtttcg cggtatgcgt tactctgaag atcacgcgca gatcaaagag
    30841 tgggcaccgt tagtgatgga agggcgcgat ccacaacaga aagtagcggc aacacgcaca
    30901 gaaattggca ctgatgtgaa ctatggcgag atcacccgcc agttaattgc ttccttacag
    30961 aagaaatcta acttctcgct gcaactcagc agcgaagtcc gcgccctaaa gcgtaatgac
    31021 gataacacct ggaccgttac cgttgccgat ctgaaaaacg gcactgcaca gaacatccgc
    31081 gccaaatttg tctttatcgg cgcgggcggt gcggcgctga agctattaca ggaatcgggg
    31141 attccggaag cgaaagacta cgccggtttc ccggtgggcg gacagttcct tgtttcggaa
    31201 aacccggacg tggttaatca ccatctggcg aaggtttacg gtaaagcatc cgttggcgca
    31261 ccaccgatgt cggttccgca tatcgatacc cgcgttctgg acggtaaacg cgtagtgctg
    31321 tttgggccat ttgccacctt ctcaaccaaa ttcctcaaaa acggttcatt gtgggatctg
    31381 atgagttcca ccaccacctc taacgtgatg ccgatgatgc acgtcgggct ggataatttc
    31441 gatctggtga aatatctggt gagtcaggtg atgttgagtg aagaggatcg ttttgaagcg
    31501 ttgaaagagt actatccgca ggcaaaaaaa gaggactggc gtttgtggca agcggggcag
    31561 cgcgtgcaga ttatcaagcg tgatgccgag aaaggtggcg tactgcgtct gggtactgaa
    31621 gtggtcagtg accagcaagg gaccattgcc gcgctgctgg gggcatcgcc aggggcgtca
    31681 accgccgcgc cgattatgtt ggatctgctg gaaaaagtat ttggcgatcg cgtttccagc
    31741 ccgcaatggc aggctacgtt gaaagcgatc gttccgtctt atggacgcaa gctgaacggt
    31801 gatgtagcgg caacagaacg cgagttgcag tacaccagcg aagtgctggg gctgaaatac
    31861 gacaagccgc aggcagcaga tagtacgcca aaaccgcagt tgaaaccgca acccgttcaa
    31921 aaagaagtgg cggatattgc gttgtaatga tgtgccacat ccggcatggt atgccggatg
    31981 tggcgtatgc tgataagacg cgccagcgtc gcatcaggca ccggctcggg cgttagatgt
    32041 cggatgcggc gtgaccgcct tattcggcct acggggtgcc gcacttcaca gcattttagc
    32101 gaactaccgc gttgtcaatt ttctcttccg ccttccagac gcggtacttc acatctacat
    32161 tgtctggcgt atacaccacg atcggcagct tgctgttgta acgcagcatt ccagcatcgc
    32221 ccagatacgc ggtgacaaat ttcttctctt tcttgccatc cgggcaggcc atcatcgtgg
    32281 aaaccggcga gctaacttta tcaaagacat aataatcata gccccagcct tccagcgttt
    32341 tgctttccag cttcccgccg agacgatgca aattgcaatc gacttccagc gtctgaccga
    32401 ttaacagttc tactttcagg gtagattcat cttcttgcgg ggttaactga atcacctgac
    32461 gcttcatccc tttttcagct tgtggataag gcgcgatttt ttccagtggc tggacgcttt
    32521 ctgccgccca ggcggaagtg gtagcgaaag cggcaaacaa tactgcaggt agaatggtct
    32581 tcattttttt gctttccttc ttcatttata ggttttcacc gatgatgtcg ctgaaggtta
    32641 acatattcat cagatttatt aatttgcttt atgaataact taaagaacat tcagacaatt
    32701 ttacctgctc ttttagtgtt aaattctgat gagggagcaa accagcagaa atatctctgg
    32761 tgaattaatc gctatataaa tatgtttata accatttgaa atgtgagcaa aagcccgttt
    32821 ttgccacgct tcccgccact cttttgatcc tgctacaggt tttaccccga tcggggtatg
    32881 catctttgac acatccttta atatcttagc ggctataaaa atggcttatt aattatgcgg
    32941 tttatttggt cgctctcaat tttcagagcg cgttaatgat ggaaggtcaa tgtgaagatt
    33001 gatgcatccc gtcggggcat actcactggt cgctggcgca aagccagtaa cggtatccgt
    33061 ccaccctggt ccggtgatga atctcatttt ctgacccatt gcacccgttg cgacgcctgt
    33121 attaatgctt gtgaaaacaa cattctgcaa cgcggcgcgg gcggctatcc gagcgttaat
    33181 ttcaaaaata acgagtgcag cttctgttac gcctgcgcgc aggcttgccc cgaatcgcta
    33241 ttttctccgc gccacaccag ggcctgggat ttgcagttca ccattgggga cgcgtgcctg
    33301 gcgtatcagt cagttgaatg ccgccgctgt caggatagct gtgagccaat ggcaattatc
    33361 tttcgcccga cgctctccgg aatctaccag ccgcaactta atagccaact ttgcaacgga
    33421 tgtggagcat gtgcagccag ctgtccggta tcagccataa ctgcggagta tctccatgca
    33481 cactaactgg caagtttgca gcctggtcgt gcaggccaaa agcgaacgaa tttcagacat
    33541 cagcacccaa ctgaacgcct ttcccggctg tgaagttgct gtcagcgacg cgccgagcgg
    33601 tcagttgatt gtggtggtgg aagcagaaga cagcgaaacg ctgatccaaa ccattgagtc
    33661 agtacgcaac gtagagggcg tgctggcggt gtcgctggtt tatcaccagc aggaagagca
    33721 aggtgaggaa acaccatgaa actcagtcgt cgtagcttta tgaaagctaa cgccgttgcg
    33781 gccgctgcgg cggctgccgg tctcagcgtg ccgggcgttg cccgcgccgt tgttggtcag
    33841 caggaagcca ttaaatggga taaagcgccg tgccgtttct gcggtactgg ttgcggcgtt
    33901 ctggtcggaa cgcagcaggg gcgtgtggtg gcctgtcagg gcgacccgga cgcaccggtt
    33961 aaccgtggcc tgaactgcat taagggctat ttcctgccca agatcatgta cggtaaagac
    34021 cgtttgacgc agccgctgct gcgtatgaaa aacggtaaat atgacaaaga aggcgaattt
    34081 accccaatca cctgggatca ggccttcgat gtgatggaag agaaattcaa aaccgccctg
    34141 aaagaaaaag gaccggaatc gatcggtatg ttcggttctg gtcagtggac tatctgggaa
    34201 ggttatgccg cgtccaagct gttcaaagcg ggcttccgtt cgaacaacat cgacccgaac
    34261 gcacgtcact gtatggcgtc ggcagtagtt ggctttatgc gtacctttgg tatggatgag
    34321 ccgatgggct gctatgacga catcgagcag gctgacgcgt ttgtgctgtg gggcgctaac
    34381 atggcggaga tgcacccgat cctctggtca cgcatcacta accgtcgtct ctctaaccag
    34441 aacgtcaccg tggcggtgct ttctacctac cagcatcgta gcttcgagct ggcggataac
    34501 ggcatcatct ttacgccgca atctgacctg gtgatcctga actacatcgc caactatatc
    34561 attcaaaaca atgcgataaa tcaggacttc ttcagcaagc acgttaacct gcgcaaaggg
    34621 gcgacggaca tcggctacgg tttacgtccg acccatccgc tggaaaaagc agcgaagaat
    34681 ccgggttctg acgcctccga accgatgagc tttgaagatt acaaagcctt cgttgctgag
    34741 tatacgctgg aaaaaactgc cgaaatgacc ggcgtgccga aagaccagtt agaacaactg
    34801 gcgcagctgt atgccgatcc gaacaagaaa gtcatctcct actggacgat gggcttcaac
    34861 cagcatactc gtggcgtgtg ggccaacaac ctggtctaca acctgcacct gctgaccggc
    34921 aaaatttccc agccgggttg cggtccgttc tccctgaccg ggcagccttc cgcgtgtggt
    34981 actgcgcgtg aagtgggcac ctttgctcac cgtctgcctg cggacatggt ggtaactaac
    35041 gagaaacatc gtgatatctg cgagaagaag tggaatatcc cgagcggcac cattccggcg
    35101 aaaatcggtc tgcatgcggt agcacaagac cgtgcgctga aagacggcaa gctgaatgtt
    35161 tactggacca tgtgtaccaa caacatgcag gccgggccga acatcaatga agagcgtatg
    35221 ccgggctggc gcgatccgcg caacttcatc atcgtctccg atccgtatcc gacagtcagt
    35281 gcgctggccg ccgacttgat cctgccgacc gcaatgtggg tagagaaaga gggcgcttac
    35341 ggtaacgccg aacgccgtac tcagttctgg cgtcagcagg tacaggcgcc aggcgaagcg
    35401 aaatcggatc tctggcagtt agtccagttc tcccgccgct tcaaaactga agaagtatgg
    35461 ccggaagagc tgctggcgaa gaaaccggaa ctgcgtggca aaacgctgta cgaagttctg
    35521 tatgccaccc ccgaagtgag caaataccct gtatccgaac tggcggaaga tcagctgaac
    35581 gatgaatccc gcgagctggg cttctatctg caaaaagggc tgttcgaaga gtacgcatgg
    35641 tttggtcgcg gtcacggtca cgatctggca ccgttcgatg actaccacaa agcgcgcggt
    35701 ctgcgctggc cggtggtgaa cggtaaagaa acgcagtggc gttacagcga aggtaacgac
    35761 ccgtacgtga aagcgggcga aggctacaag ttctacggta aaccggatgg caaagcggtg
    35821 atcttcgcgc tgccgttcga accggcggcg gaagcaccgg atgaagagta cgacctgtgg
    35881 ctctctaccg gacgcgttct ggagcactgg cacaccggca gtatgactcg ccgtgtacca
    35941 gaactgcacc gcgccttccc ggaagcggtc ctgtttattc acccgctgga tgcgaaagcg
    36001 cgcgatctgc gtcgtggcga caaagtgaaa gtggtttctc gccgtggcga agtgatctcg
    36061 attgtcgaaa cgcgcggtcg taaccgtccg ccacagggcc tggtgtacat gccgttcttc
    36121 gacgccgcac agctggttaa caaactgacg ctggatgcga ccgatccgct ctcgaaagag
    36181 acggacttca agaagtgcgc agtcaaactg gagaaggtgt aagccattat gtcccggtca
    36241 gcgaaacctc aaaatggtcg ccgccgcttt ctgcgcgatg tcgttcgcac agcaggcggg
    36301 ctggctgccg tgggtgtggc gctggggtta caacagcaaa ccgcacgcgc atctggcgtg
    36361 cggttgcgcc cgcccggagc cataaacgag aacgcctttg ccagtgcctg tgtgcgttgc
    36421 ggtcagtgtg ttcaggcttg cccttacgac accttaaaac tggcgacgct ggcttctggc
    36481 ctgtcggcgg gcacgccata ttttgtcgca cgggatattc cttgcgaaat gtgtgaggac
    36541 attccgtgcg ccaaagtgtg cccaagcggt gcgctggatc gtgagattga atcgatcgac
    36601 gacgcgcgga tggggctggc ggtactggtg gaccaggaaa actgtctcaa ctttcagggg
    36661 ctgcgctgcg atgtttgtta tcgcgaatgc ccgaaaattg atgaggccat caccctggag
    36721 ctggagcgca acacgcgtac cggtaagcac gcccgctttc tgccgacggt tcacagcgac
    36781 gcctgtaccg gttgcggtaa gtgcgaaaaa gtatgcgtgc tggaacaacc ggcaatcaag
    36841 gtgttaccgc tgtcactggc gaaaggggag ttaggtcacc attaccgctt cggctggctg
    36901 gaggggaaca atggcaaatc gtaaacgtga cgccgggcgc gaggcgctgg agaaaaaagg
    36961 ctggtggcgc agtcaccgtt ggctggtgtt acgtcgcctt tgtcagttct tcgtgctggg
    37021 gatgtttttg agcggtccgt ggtttggtgt gtggatctta cacggtaact acagcagtag
    37081 cctgttattc gacaccgttc cgctgaccga tccgctgatg acgctgcaaa gtcttgccag
    37141 tggtcatctg cctgccacgg tggcgttgac cggtgcggtg attatcaccg tgctctacgc
    37201 cctggcggga aagcgattat tttgcagctg ggtctgcccg ctgaacccga ttaccgactt
    37261 agcgaactgg ttacgcaggc gctttgacct caatcagtct gcgacgatcc ctcgccacat
    37321 tcgctacgtg ctgttggtgg tcattctggt gggatcagcc ttaactggca cgctcatttg
    37381 ggaatggatc aaccccgttt ctctgatggg gcgcagcctg gtaatgggct tcggcagcgg
    37441 cgcgctgctt attctcgcgc tgtttttatt tgatctactg gtcgttgaac acggctggtg
    37501 cgggcacatt tgtccggttg gcgcgctgta tggcgtgctg ggtagcaaag gtgtgattac
    37561 cgttgcggcc accgatcggc agaaatgtaa ccgctgtatg gattgttttc atgtttgccc
    37621 ggaaccgcat gtgctacgtg ccccggtgct ggatgaacaa agcccggtgc aggtcaccag
    37681 ccgcgattgc atgacgtgcg gtcgctgcgt ggatgtctgt tctgaggatg tatttacaat
    37741 aactacacga tggagttcgg gagcgaaatc atgaaaagcc atgacctgaa gaaagcgctg
    37801 tgtcaatgga cggcgatgct ggccctggtg gtaagcggcg cggtttgggc ggctaatggc
    37861 gtcgatttta gccagtcgcc ggaagtatcc gggacacagg aaggggccat tcggatgcca
    37921 aaagagcagg aacggatgcc gctgaactat gtgaatcagc cgccaatgat cccgcatagc
    37981 gttgaaggtt atcaggtaac gaccaatacc aaccgctgct tgcagtgcca cggtgtcgaa
    38041 agttatcgca ccactggcgc gccgcgtatc agtcctactc actttatgga cagcgacggc
    38101 aaagtgggcg cggaagtggc tccgcgtcgt tatttctgtc tgcaatgtca cgtaccgcag
    38161 gccgataccg cgccaatcgt ggggaatacc tttaccccat caaaaggtta cgggaaataa
    38221 gaggttatta tgggaaattc tgaccgtaag cctggtctga ttaagcgcct gtggaaatgg
    38281 tggcgtaccc ccagccgtct ggcgctgggg acgctgctgt tgatcggttt tgttggcggc
    38341 atcgtcttct ggggtggctt taacaccggg atggaaaaag ccaataccga agagttctgc
    38401 attagctgcc acgaaatgcg caacacggtg tatcaggaat acatggattc cgtgcactac
    38461 aacaaccgta gcggcgtccg tgcgacctgt ccggattgtc acgttccgca cgagtttgtg
    38521 ccgaagatga tacgcaagct caaagcaagt aaagagctgt atggtaaaat ttttggcgtt
    38581 attgacacgc cgcagaaatt tgaagctcat cgtctgacga tggcacagaa tgagtggcgg
    38641 cgcatgaagg acaataactc gcaggagtgc cgtaactgtc acaacttcga gtatatggat
    38701 acaaccgccc agaaatcggt tgccgcgaag atgcatgacc aggcggtgaa agatgggcaa
    38761 acctgtattg attgccataa agggatagcg cacaagctgc ccgatatgcg tgaagtcgag
    38821 ccaggttttt aacagggtta ttgcgtgggt atgcttgaag ccagagagtt actttgtgag
    38881 cgggatgaac gaaccttatt tagtggcttg tcatttacgc tgaacgcagg agagtgggta
    38941 caaatcaccg gtagcaacgg cgcggggaag acaacgcttc tccgtttgct gacggggttg
    39001 tctcgccctg acgcaggcga ggttctctgg caagggcagc ccttgcatca ggtacgcgac
    39061 agctaccatc aaaacctgtt atggataggc catcagccgg ggatcaaaac ccggctgacg
    39121 gcgttagaaa atctgcactt ttatcatcgc gatggcgata ccgcacaatg tctggaagcc
    39181 ctggcgcagg ccgggcttgc cggattcgaa gatattcctg taaatcagct ctcggccggg
    39241 caacaacgcc gcgtcgcttt agcgcgtctg tggctgaccc gtgccacgtt atggatcctc
    39301 gacgagcctt ttaccgcgat tgacgttaac ggcgtcgatc gtctgaccca gcgtatggcg
    39361 cagcatacgg agcagggggg gattgtgatt ctgactaccc accagccgct caacgttgct
    39421 gaaagtaaaa ttcgccgcat ttcactgacg caaacgaggg ccgcatgatg ttctggcgca
    39481 ttttccgtct tgagctgcgt gtagcgtttc gccatagcgc cgaaatcgcc aacccgctgt
    39541 ggttcttcct gattgtaatt accctttttc cgctcagtat cggtccggag ccgcaactgc
    39601 tggcgcgtat tgcaccgggc attatctggg ttgctgcgct gctttcatcc ttgctggcgc
    39661 tggaacgact gttccgtgac gatttgcagg acggcagtct tgaacaattg atgttgttgc
    39721 cgttaccctt gcccgccgtt gtgctggcga aggtgatggc gcactggatg gtaaccggtc
    39781 tgccgttact catcctttcg ccactggtag caatgctact gggaatggat gtttatggct
    39841 ggcaagtgat ggcgctgacg cttctgctgg gaacgcctac gcttggcttt ctcggtgcac
    39901 cgggtgtggc gttgacagtg ggacttaagc gcggtggtgt gctgctcagc atactggtgt
    39961 taccgctgac tatcccatta ctcatctttg ccaccgccgc gatggacgcg gcttccatgc
    40021 atttgcccgt tgacgggtat ctggcaattt taggcgcgtt gctggcaggc accgcgacat
    40081 taagtccttt tgcgacggcg gcagcgttac gaatcagcat tcaataacgc tggattactg
    40141 atttttgttc gagtctggta tcgaaactat gtggaaaaca ctgcatcaac tggcgatccc
    40201 tccacggctg tatcaaatct gtggctggtt tataccgtgg ctggcaattg ccagtgtggt
    40261 cgtgcttacc gtcggctgga tctggggatt cggctttgct ccggctgatt atcagcaggg
    40321 aaatagctac cgcattatct acctgcatgt gcctgcggcg atctggtcga tgggcattta
    40381 tgcatcaatg gcggtggcgg cttttattgg ccttgtctgg cagatgaaaa tggccaacct
    40441 ggcggtggcg gcgatggccc ccattggtgc cgtgtttacc tttattgccc tggttaccgg
    40501 ctctgcatgg ggaaaaccga tgtggggcac ctggtgggta tgggatgcac gtctgacttc
    40561 tgaactggtg ctgctgtttt tgtatgtggg tgtgattgcc ctgtggcacg ccttcgacga
    40621 ccgccgtctg gcgggccgtg cggcaggtat cctggtgctg attggcgtgg tgaatctgcc
    40681 gattattcat tactccgtgg agtggtggaa caccctgcat cagggatcaa cgcggatgca
    40741 gcaaagtatc gatccggcga tgcgttcgcc gctgcgctgg tcgatttttg gcttcctgct
    40801 gctgtctgcc acgctgacgc tgatgcggat gcgtaatttg attttgctga tggaaaaacg
    40861 ccgtccgtgg gtgagtgaac tgatactgaa aagaggccgt aaatgacccc tgcatttgct
    40921 tcctggaatg aatttttcgc aatgggcggt tacgcctttt ttgtctggct ggcggtggtg
    40981 atgaccgtta ttccgctggt ggttttggtc gtgcactcgg tgatgcagca tcgcgcaatt
    41041 ctgcgtggtg tggcgcaaca gcgggcgcgt gaggcgcgtt tacgtgctgc gcaacagcag
    41101 gaggctgcat gaatattcgc cgtaaaaacc gcttgtggat tgcctgtgcc gtgttggcag
    41161 ggctggcgct gactatcggt ctggtgctat atgcgctgcg ctcgaatatc gatctctttt
    41221 atacgccggg ggaaattctc tacggcaagc gtgaaactca gcaaatgccg gaagtcgggc
    41281 agcgtctgcg cgtcggcggg atggtgatgc cgggtagcgt gcagcgcgat cccaattcgc
    41341 taaaagtaac tttcaccatt tacgacgctg aaggttcagt agatgtctct tacgaaggca
    41401 ttttgccgga tctgttccgt gaagggcagg gcgttgtggt gcagggcgag ctggaaaaag
    41461 gcaatcatat cctcgcgaaa gaagtgctgg cgaaacacga cgaaaactac acgccgccag
    41521 aagttgagaa agcgatggaa gctaaccacc gtcgcccggc gagtgtttat aaggacccag
    41581 catcatgatg ccggaaattg gaaacgggct gctgtgcctg gcgttaggga ttgcgctgct
    41641 gctgtccgtg tatccgctat ggggcgtggc gcgcggagat gcgcgcatga tggcgtcttc
    41701 ccgcttgttt gcctggctgc tgtttatgtc tgtggctggc gcatttctgg tgctggtcaa
    41761 tgctttcgtg gtcaacgact ttaccgtcac ctatgttgcc agcaactcca atacccagct
    41821 tccggtgtgg tatcgcgtgg cggctacctg gggcgcgcat gaaggctcgc tactgctgtg
    41881 ggtgctgctg atgagcggct ggacctttgc ggtggcgatt tttagtcagc gtattccgct
    41941 ggatattgtg gcccgcgtac tggcgataat ggggatggtc agcgtcggct ttttgctgtt
    42001 cattctcttt acctctaacc cattctcacg cacgctgccg aacttcccga ttgaagggcg
    42061 cgatcttaac ccgctgttac aggatccggg gctgatcttc catccgcctc tgctttatat
    42121 ggggtacgtg ggtttctcgg tggcgtttgc ttttgccatt gcttctttgt tgtgcgggcg
    42181 tctggacagc acttatgcgc gttttactcg tccgtggacg ctggcggcgt ggatcttctt
    42241 gacgctcggc attgtgctcg gttccgcatg ggcctattac gaactcggct ggggcggctg
    42301 gtggttctgg gatccggtag aaaacgcctc gtttatgccg tggctggtgg ggactgcgct
    42361 gatgcactca ctggcggtca ctgaacaacg cgccagcttc aaagcgtgga cattactgct
    42421 ggcaatcagt gccttctcgt tgtgtctgct ggggactttc ctggtgcgtt ccggcgtgct
    42481 ggtatcggta cacgcgtttg cctctgatcc ggcacgcggt atgtttatcc tcgcctttat
    42541 ggtactggtg attggtggtt cgctgctgct gtttgccgcg cgtggacaca aagttcgctc
    42601 acgcgtaaac aatgcgctgt ggtcgcggga atctctgctg ttagcgaaca acgttttgct
    42661 ggtcgccgcg atgctggtgg tattactggg gacgctgctg ccgctggtgc acaagcaact
    42721 gggactgggc agtatttcga ttggcgaacc gttcttcaac accatgttta cctggctgat
    42781 ggtgccgttt gcgctgctgc ttggtgtcgg tcctctggtg cgctgggggc gcgatcgccc
    42841 acgtaaaatc cgcaatttat tgattatcgc cttcatctca acgctggtgc tgtcgctgct
    42901 gctgccgtgg ctgttcgaaa gcaaagttgt ggcgatgacg gtgctcggcc tggcaatggc
    42961 ctgctggatt gctgtgctgg caattgcgga agctgcgctg cgtatttcac gtggcacgaa
    43021 aaccaccttc agttattggg gaatggtggc ggctcacctg gggctggcag tgacaattgt
    43081 tggtattgcc tttagccaga actatagcgt tgagcgtgat gtgcgcatga agtccggcga
    43141 tagcgtcgat attcatgaat atcgcttcac cttccgtgat gtcaaagagg tgactggccc
    43201 gaactggcgt ggcggtgtgg cgactatcgg cgtaacgcgc gatggcaagc cggaaacggt
    43261 gctgtatgcg gaaaaacgtt attacaacac tgccgggtcg atgatgaccg aagcggcaat
    43321 tgacggcggc atcacgcgtg acctgtacgc cgcgctcggt gaagagctgg aaaacggcgc
    43381 gtgggccgtg cgtctttact acaaaccatt tgttcgctgg atttgggcgg gcgggctgat
    43441 gatggcgttg ggcggactgc tgtgtctgtt tgatcctcgc tatcgtaagc gcgtgagtcc
    43501 gcaaaaaact gcgccggagg ccgtatgaag cgcaaagtat tgttaattcc gttgattatc
    43561 ttcctggcga ttgccgcggc gctgctgtgg cagctggcgc gtaatgccga aggggatgat
    43621 ccgaccaatc tggaatcggc gctcattggc aagcctgtgc cgaagtttcg tctcgaatca
    43681 ctggacaatc cggggcagtt ttatcaggcg gatgtgctga ctcagggcaa accagtgctg
    43741 cttaacgtct gggcgacctg gtgtccgacc tgccgtgcgg aacatcaata tctgaatcag
    43801 ctttcagcgc agggcattcg cgtggtcggc atgaactata aagacgatcg ccagaaggca
    43861 atcagctggc tgaaagagct gggcaatcct tacgcgctaa gcctgtttga tggcgacggc
    43921 atgttagggc tggatctcgg tgtctatggc gcgccagaaa ccttccttat tgacggcaac
    43981 ggtatcattc gctatcgcca tgcgggcgat ctcaatcctc gcgtctggga agaagagatc
    44041 aagccgctgt gggagaaata cagtaaggag gccgcacaat gaggttttta ttgggcgtgc
    44101 tgatgctgat gatctccggc tcagcactgg cgaccatcga cgtgttgcag tttaaagatg
    44161 aagcacagga acaacagttc cgtcagctca ctgaagaact gcgctgcccg aaatgccaga
    44221 acaacagcat tgccgattcc aactcgatga ttgccaccga cctgcgtcag aaagtgtatg
    44281 aactgatgca ggaaggtaaa agtaaaaaag agattgtcga ttatatggtg gcgcgttacg
    44341 gcaacttcgt cacttacgat ccgccgttaa cgccgctgac cgtgctgctg tgggtgcttc
    44401 cggtagtggc tattggcatt ggcggttggg tcatatacgc ccgctcgcgg cgtcgggtac
    44461 gcgtagtgcc ggaagcgttt cctgaacaaa gcgtgcagga aggtaagcgt gccggatata
    44521 ttgtttatct gccgggtatt gtggtggcgt taattgtggc tggcgtcagc tactaccaga
    44581 ctggcaatta tcagcaggtg aaaatctggc agcaggccac ggcacaggct ccggcgttgc
    44641 tggacagggc gctggatccg aaagccgatc cgctcaacga agaagagatg tcgcgtcttg
    44701 cgctggggat gcgtactcaa ctgcaaaaaa atccgggaga tatagaaggc tggattatgt
    44761 tgggccgcgt tggcatggcg ctgggtaacg ccagtatcgc caccgatgca tacgctactg
    44821 cgtatcgcct cgatccgaaa aacagtgatg ccgcactggg ttatgctgaa gcgttgacac
    44881 gttcatctga tcccaacgac aaccgcctcg gcggcgaact gctgcgccag ttggtgagaa
    44941 cggaccatag caatatccgt gtgctaagca tgtatgcgtt taatgccttt gagcagcagc
    45001 gatttggcga agccgttgcc gcgtgggaga tgatgttgaa actcttacct gccaacgata
    45061 ctcgccgtgc ggtgattgaa cgtagtatcg cgcaggcgat gcaacatttg tcgctgcagg
    45121 agagtaaata aaaagaggcc cgatggtgat gccatcgggc tatttttatt gtgccccgcg
    45181 ttgttgcagg aacagaatgg tggccgccac gcgtgagcgg acattgagtt tacgcagcag
    45241 attgcgaata tgtactttta ctgtctgctc ggaaatattc aataccgagg caatctgttt
    45301 atttgacagc ccctgtgcca gctcgtgcag aacatccagc tcgcgctccg tcagcacgct
    45361 gaagggatct tcttccgcgc caaacatttc acgttcacgt aagtactgat tgacgcgttc
    45421 gctaaagact ttgctgcctt tcgctccggc acgaatcgct tccagcaata cttccgggtc
    45481 gctgtctttc aacagataac cgtctgcgcc tgcgtctatc agcgcaaaga catcgctgga
    45541 ggcatcggat acggtcagga taataatttg cgcggtaacg ccatccctgc gcaaggcatt
    45601 gagggtatcc aggccactca tacctttcat attgagatcc agcaagatca cgtcgatatc
    45661 cagtctattc gccagatcga tcgcgctcgc gccgtcgccc gcttcggcga ccacttcaaa
    45721 gccaggatca agctccagta actgacgaac accgcgtcgc ataagtggat gatcatccac
    45781 aatcatcacc tgaaaaggcg ttgcttcagg catagtagtc tcctgaggtt ttattagaat
    45841 cattatgttt gagcgtagcg ttggtaacgc taccaggcgc gtgaatgtta ccccatttta
    45901 tgtatggaca tgtagtgaaa actacaacct tgtcgttcgc tttggcatca ttttcattat
    45961 aaagacggaa ttttgcatca gcttctcatc aagaaaaaca actaaaaaat caatcacaat
    46021 acttgtgcat ttctttaaac agtttttaaa aactgactcc gggtatggag ctatgggtat
    46081 tttccgtacc caatgctttt aacagcaatt aatttcatag gatgaaagct caattcatca
    46141 atctggttct gtttctcttt gtcgttccgc aatatctgtt ctggtggcta cagcgttata
    46201 ttcacccata gcattggcat caacagttga gtatggtgag acagttgatg gtgttgtcct
    46261 ggaaaaagat atccagctgg tttatgggac cgccaataat acgaaaatca atcctggcgg
    46321 agaacagcat ataaaagaat ttggtgtaag tagtaatact gaaattaaag gagggtatca
    46381 gtacattgaa atgaatggta ccgcagaata ctcagtatta aatgacggtt atcaaattgt
    46441 tcaaatgggt ggcgcggcaa accagactac cctcaataat ggtgtgctac aggtttatgg
    46501 cgcagcgaat gatcccacga ttaaaggcgg gcgcttaatc gttgaaaaag atgggattac
    46561 cgtccttgcc gctatcgaaa agggaggatt actggaggtt aaagaggggg gattagcgat
    46621 tgcggtagat cagaaagcag gcggtgctat taaagcaagc acgcgggtca tggaggcatt
    46681 cggaacaaac cgtctcggtc agttcgaaat caagaatggt attgctaaca atatgctgtt
    46741 ggaaaacggc ggaagtttgc gagttgaaga aaatgacttc gcttataata ctactgtaga
    46801 tagtggcggc ttactggagg ttatggatgg cgggactgta actggcgttg ataaaaaagc
    46861 aggcggaaaa ttaattgtct caacgaatgc gctggaagtg agtggtacaa acagtaaagg
    46921 ccaatttagt ataaaagatg gtgtgtcaaa aaattatgaa ctggatgatg gttccgggct
    46981 cattgttatg gaggacacgc aggccattga tactatcctt gatgagcatg ccactatgca
    47041 atcgctggga aaggatactg gtacgaaagt gcaggcaaat gcggtatatg atctcggtcg
    47101 atcagatcag aatggaagta tcacgtattc ctcaaaagcc atttctgaaa atatggttat
    47161 caacaatggc cgcgctaacg tctgggctgg cacaatggtt aacgtttcag tcagagggaa
    47221 tgatggcatt cttgaggtca tgaagccgca aataaattat gcacccgcaa tgttggtggg
    47281 taaggtagtg gtttctgagg gcgcttcttt tagaacgcat ggtgccgtgg ataccagcaa
    47341 agcggacgtt tcgctcgaaa atagcgtatg gaccatcatt gccgatatca ctacgacgaa
    47401 ccaaaacacc ctcctcaact tagccaacct tgcgatgtct gacgcaaatg tgattatgat
    47461 ggatgagcca gtgactcgtt catcagtgac ggcaagtgcg gaaaatttca ttacgttgac
    47521 caccaatacc ctgtcgggaa acggcaattt ttatatgcgt accgatatgg ctaatcatca
    47581 gagcgatcag ctcaacgtca ccggtcaggc aacaggtgat ttcaaaatat tcgtgacgga
    47641 caccggtgcc agcccggcag caggagatag ccttacactg gtaacaacgg gcggcggtga
    47701 tgctgcattt acgttgggca atgccggagg cgttgttgat atcggtacgt atgaatatac
    47761 cttgctggat aatggcaacc atagctggag tttggcagag aatcgcgcgc aaattacccc
    47821 ttcaaccact gatgtgctga atatggcggc agcacaaccg ctggtatttg atgcagaact
    47881 ggacaccgtg cgtgagcgtc ttggtagcgt aaaaggcgtt aattacgata cggcgatgtg
    47941 gagttcggca attaacaccc gcaacaacgt gaccactgat gcgggcgctg gctttgagca
    48001 aacattgacc gggctgacgc tcggtatcga tagccgtttc tcccgtgaag aaaccagcac
    48061 aattcgcggc ttgttctttg gttactctca ttctgatatt ggttttgatc gcggcggcaa
    48121 aggcaatgtc gatagctata ccctgggggc ttatgccggt tgggagcatc agaacggtgc
    48181 ctatgttgat ggagtggtga aagttgaccg ttttgccaac accatccatt gcaagatgag
    48241 taatggggca acagcgtttg gcgattacaa tagtaacggc gcgggtgctc atgtcgagag
    48301 cgggttccgt tgggttgacg gattgtggag tgttagaccc tatctggcct ttaccggctt
    48361 taccacagat ggtcaggact acacgttatc aaacggcatg cgcgcggatg tgggaaatac
    48421 ccggatatta cgcgctgaag cgggaacggc ggtaagctat cacatggacc tgcaaaacgg
    48481 tacgacgctg gaaccctgac tgaaagccgc cgtgcgtcag gaatacgccg attctaacca
    48541 ggtgaaagtt aatgacgatg gcaaatttaa taatgatgtg gctggaaccc gtggcgttta
    48601 tcaggctggg ataaggtcat cgtttacccc gacgttaagc ggtcatttgt cagtcagcta
    48661 tggcaatggc gcaggggtag aatcgccgtg gaatactcag gcgggtgtgg tctggacgtt
    48721 ctgataacaa aaaataaaca ggctgtgatg tgtcacggtc tgtttatcga attaattgca
    48781 gatataaaaa aaaccaaccg taaaggttga ttttttcttg ggatttttgg tcggcacgag
    48841 aggatttgaa cctccgaccc ccgacacccc atgacgccgc ttgaaaaatg ctgagaaccg
    48901 cgcaatcgct ggtggtaggt actattcgca tgtataaaca aacagtgctt ttttagcaaa
    48961 atccgttcta tatacatcaa tgacttaggt ggtggtttct ccccatgcca caagtagtgt
    49021 tgagctttac tgaagccact ccattggcct ctacatggaa actaacaaga aaatgtcagt
    49081 tgaaggagtt ttataaattc atgttttctt cttcaggaca acccatcacc cgcaggcacc
    49141 gcctgcggga attttgcgac tgtgttcgtt ttaaattata gatgcatcac ctgatattcg
    49201 tgacatacaa act
//
LOCUS       DAPGUL010000020        48806 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.020, whole genome shotgun sequence.
ACCESSION   DAPGUL010000020 DAPGUL010000000
VERSION     DAPGUL010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 48806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48806
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.020"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(11..736)
                     /gene="phoU"
                     /locus_tag="RHX21_001311"
     CDS             complement(11..736)
                     /gene="phoU"
                     /locus_tag="RHX21_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HDV1986528.1"
                     /translation="MDSLNLNKHISGQFNAELESIRTQVMTMGGMVEQQLSDAITAMH
                     NQDSDLAKRVIEGDKNVNMMEVAIDEACVRIIAKRQPTASDLRLVMVISKTIAELERI
                     GDVADKICRTALEKFSQQHQPLLVSLESLGRHTIQMLHDVLDAFARMDIDEAVRIYRE
                     DKKVDQEYEGIVRQLMTYMMEDSRTIPSVLTALFCARSIERIGDRCQNICEFIFYYVK
                     GQDFRHVGGDELDKLLAGKDSDK"
     gene            complement(751..1524)
                     /gene="pstB"
                     /locus_tag="RHX21_001312"
     CDS             complement(751..1524)
                     /gene="pstB"
                     /locus_tag="RHX21_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HDV1986529.1"
                     /translation="MSMVETAPSKIQVRNLNFYYGKFHALKNINLDIAKNQVTAFIGP
                     SGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDNILTNSQDIALLRAKVGMVFQKPTP
                     FPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQ
                     RLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKQDYTVVIVTHNMQQAARC
                     SDHTAFMYLGELIEFSNTDDLFTKPAKKQTEDYITGRYG"
     gene            complement(1707..2597)
                     /gene="pstA"
                     /locus_tag="RHX21_001313"
     CDS             complement(1707..2597)
                     /gene="pstA"
                     /locus_tag="RHX21_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HDV1986530.1"
                     /translation="MAMVEMQTTAALAESRRKMQARRRLKNRIALTLSMATMAFGLFW
                     LIWILMSTITRGIDGMSLALFTEMTPPPNTEGGGLANALAGSGLLILWATVFGTPLGI
                     MAGIYLAEYGRKSWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMEHFSGWAGVIAL
                     ALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMISAITLKASVSGIMTGILLAI
                     ARIAGETAPLLFTALSNQFWSTDMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLIIT
                     LCVLLLNILARVVFAKNKHG"
     gene            complement(2597..3556)
                     /gene="pstC"
                     /locus_tag="RHX21_001314"
     CDS             complement(2597..3556)
                     /gene="pstC"
                     /locus_tag="RHX21_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008806729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstC"
                     /protein_id="HDV1986531.1"
                     /translation="MAATKPAFNPPGKKGDIIFSVLVKLAALIVLLMLGGIIVSLIIS
                     SWPSIQKFGLAFLWTKEWDAPNDIYGALVPIYGTLVTSFIALLIAVPVSFGIALFLTE
                     LAPGWLKRPLGIAIELLAAIPSIVYGMWGLFIFAPLFAVYFQEPVGNIMSNIPIVGAL
                     FSGPAFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRI
                     VLPFTKNGVIGGIMLGLGRALGETMAVTFIIGNTYQLDSASLYMPGNSITSALANEFA
                     EAESGLHVAALMELGLILFVITFIVLAASKFMIMRLAKNEGAR"
     gene            complement(3643..4683)
                     /gene="pstS"
                     /locus_tag="RHX21_001315"
     CDS             complement(3643..4683)
                     /gene="pstS"
                     /locus_tag="RHX21_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HDV1986532.1"
                     /translation="MKVMRTTVATVVAATLSMSAFSVFAEASLTGAGATFPAPVYAKW
                     ADTYQKETGNKVNYQGIGSSGGVKQIIANTVDFGASDAPLSDEKLAQEGLFQFPTVIG
                     GVVLAVNIPGLKSGELVLDGKTLGDIYLGKIKKWDDEAIAKLNPDLKLPSQNIAVVRR
                     ADGSGTSFVFTSYLAKVNEEWKNNVGTGSTVKWPIGLGGKGNDGIAAFVQRLPGAIGY
                     VEYAYAKQNNLAYTKLISADGKPVLPTEENFANAAKGADWSKTFAQDLTNQKGEDAWP
                     ITSTTFILVHKDQKKPEQGVEVLKFFDWAYKTGAKQANDLDYASLPDSVVEQVRAAWK
                     TNIKDSSGKPLY"
     gene            5486..5725
                     /locus_tag="RHX21_001316"
     CDS             5486..5725
                     /locus_tag="RHX21_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1819 family protein"
                     /protein_id="HDV1986533.1"
                     /translation="MTPFRYNSDLTSGSLQTRECRIITGLLLQELDEAAWDKAMYKEN
                     VLQKRTQSTVRRISSALRKRLEHLSSDFWAFAFLC"
     gene            complement(5913..6890)
                     /gene="intI2"
                     /locus_tag="RHX21_001317"
                     /pseudo
     CDS             complement(5913..6890)
                     /gene="intI2"
                     /locus_tag="RHX21_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_023994230.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class 2 integron integrase IntI2"
     gene            7222..7695
                     /locus_tag="RHX21_001318"
     CDS             7222..7695
                     /locus_tag="RHX21_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001355915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrA1"
                     /protein_id="HDV1986534.1"
                     /translation="MKLSLMVAISKNGVIGNGPDIPWSAKGEQLLFKAITYNQWLLVG
                     RKTFESMGALPNRKYAVVTRSSFTSDNENVLIFPSIKDALTNLKKITDHVIVSGGGEI
                     YKSLIDQVDTLHISTIDIEPEGDVYFPEIPSNFRPVFTQDFASNINYSYQIWQKG"
     gene            7790..8314
                     /gene="sat2"
                     /locus_tag="RHX21_001319"
     CDS             7790..8314
                     /gene="sat2"
                     /locus_tag="RHX21_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat2"
                     /protein_id="HDV1986535.1"
                     /translation="MKISVIPEQVAETLDAENHFIVREVFDVHLSDQGFELSTRSVSP
                     YRKDYISDDDSDEDSACYGAFIDQELVGKIELNSTWNDLASIEHIVVSHTHRGKGVAH
                     SLIEFAKKWALSRQLLGIRLETQTNNVPACNLYAKCGFTLGGIDLFTYKTRPQVSNET
                     AMYWYWFSGAQDDA"
     gene            8372..9160
                     /gene="aadA1"
                     /locus_tag="RHX21_001320"
     CDS             8372..9160
                     /gene="aadA1"
                     /locus_tag="RHX21_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014325834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA1"
                     /protein_id="HDV1986536.1"
                     /translation="MREAVIAEVSTQLSEVVGVIERHLEPTLLAVHLYGSAVDGGLKP
                     HSDIDLLVTVTVRLDETTRRALINDLLETSASPGESEILRAVEVTIVVHDDIIPWRYP
                     AKRELQFGEWQRNDILAGIFEPATIDIDLAILLTKAREHSVALVGPAAEELFDPVPEQ
                     DLFEALNETLTLWNSPPDWAGDERNVVLTLSRIWYSAVTGKIAPKDVAADWAMERLPA
                     QYQPVILEARQAYLGQEDRLASRADQLEEFVHYVKGEITKVVGK"
     gene            9236..9733
                     /locus_tag="RHX21_001321"
     CDS             9236..9733
                     /locus_tag="RHX21_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001444089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986537.1"
                     /translation="MRDLLKVVLSLVLAMASGQALADLPIVLVDEARLPYDYSPSNYD
                     ISPSNYDNSISNYDNSPSNYDNSESNYDNSSSNYDNSRNGNRRLIYSANGSRTFAGYY
                     VIANNGTTNFFSTSGKRMFYTPKGGRGVYGGKDGSFCGALVVINGQFSLALTDNGLKI
                     MYLSN"
     gene            9794..10165
                     /locus_tag="RHX21_001322"
     CDS             9794..10165
                     /locus_tag="RHX21_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986538.1"
                     /translation="MSYEPPRDGYTNGYIVDVMYDNRPSKYPAVFRTYVRIPDYVELD
                     NAEELADAIIREVELKEAWLTRVLGNSADPDASVGKWDRRLAQCGGIDEMSSGVQATY
                     FSPNGQLVGLVAYIDAEWMDE"
     gene            10575..10952
                     /locus_tag="RHX21_001323"
     CDS             10575..10952
                     /locus_tag="RHX21_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001271300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986539.1"
                     /translation="MSAAKALAYALCDKLESKKVDEVVRNLVSSGWNIREVAWEASSF
                     DHEMPYFDTGRDFDIGFPDTLSSKIEFLTANGSIVQARARLHFKQALIFAKASKHVAA
                     LKNSLDYYYGSSVIPPQNHGGYL"
     gene            10975..11127
                     /locus_tag="RHX21_001324"
                     /pseudo
     CDS             10975..11127
                     /locus_tag="RHX21_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011069623.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(11183..12799)
                     /locus_tag="RHX21_001325"
     CDS             complement(11183..12799)
                     /locus_tag="RHX21_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional antiterminator"
                     /protein_id="HDV1986540.1"
                     /translation="MVRLATFNDNVQVVHIGHLFRNSGHKEWRIFVWFNPMQERKWTR
                     FTHLPLLSRAKVVNSTTKQINKADRVIEFEASDLQRAKIIDFPNLSSFASVRNKDGAQ
                     SSFIYEAETPYSKTRYHIPQLELARSLFLINSYFCRSCLSSTALQQEFDVQYEVERDH
                     LEIRILPSSSFPKGALEQSAVVQLLVWLFSDQDVMDSYESIFRHYQQNREIKNGVESW
                     CFSFDPPPMQGWKLHVKGRSSNEDKDYLVEEIVGLEINAMLPSTTAISHASFQEKEAG
                     DGSTQHIAVSTESVVDDEHLQLDDEETANIDTDTRVIEAEPTWISFSRPSRIEKSRRA
                     RKSSQTILEKEEATTSENSNLVSTDEPHLGGVLAAADVGGKQDATNYNSIFANRFAAF
                     DELLSILKTKFACRVLFEETLVLPKVGRSRLHLCKDGSPRVIKAVGVQRNGSEFVLLE
                     VDASDGVKMLSTKVLSGVDSETWRNDFEKIRRGVVKSSLNWPNSLFDQLYGQDGHRGV
                     NHPKGLGELQVSREDMEGWAERVVREQFTH"
     gene            complement(12800..14326)
                     /locus_tag="RHX21_001326"
     CDS             complement(12800..14326)
                     /locus_tag="RHX21_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001243518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TniQ family protein"
                     /protein_id="HDV1986541.1"
                     /translation="MRNFPVPYSNELIYSTIARAGVYQGIVSPKQLLDEVYGNRKVVA
                     TLGLPSHLGVIARHLHQTGRYAVQQLIYEHTLFPLYAPFVGKERRDEAIRLMEYQAQG
                     AVHLMLGVAASRVKSDNRFRYCPDCVALQLNRYGEAFWQRDWYLPALPYCPKHGALVF
                     FDRAVDDHRHQFWALGHTELLSDYPKDSLSQLTALAAYIAPLLDAPRAQELSPSLEQW
                     TLFYQRLAQDLGLTKSKHIRHDLVAERVRQTFSDEALEKLDLKLAENKDTCWLKSIFR
                     KHRKAFSYLQHSIVWQALLPKLTVIEALQQASALTEHSITTRPVSQSVQPNSEDLSVK
                     HKDWQQLVHKYQGIKAARQSLEGGVLYAWLYRHDRDWLVHWNQQHQQERLAPAPRVDW
                     NQRDRIAVRQLLRIIKRLDSSLDHPRATSSWLLKQTPNGTSLAKNLQKLPLVALCLKR
                     YSESVEDYQIRRISQAFIKLKQEDVELRRWRLLRSATLSKERITEEAQRFLEMVYGEE
                     "
     gene            complement(14329..15996)
                     /locus_tag="RHX21_001327"
     CDS             complement(14329..15996)
                     /locus_tag="RHX21_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDV1986542.1"
                     /translation="MSATRIQAVYRDTGVEAYRDNPFIEALPPLQESVNSAASLKSSL
                     QLTSSDLQKSRVIRAHTICRIPDDYFQPLGTHLLLSERISVMIRGGYVGRNPKTGDLQ
                     KHLQNGYERVQTGELETFRFEEARSTAQSLLLIGCSGSGKTTSLHRILATYPQVIYHR
                     ELNVEQVVYLKIDCSHNGSLKEICLNFFRALDRALGSNYERRYGLKRHGIETMLALMS
                     QIANAHALGLLVIDEIQHLSRSRSGGSQEMLNFFVTMVNIIGVPVMLIGTPKAREIFE
                     ADLRSARRGAGFGAIFWDPIQQTQRGKPNQEWIAFTDNLWQLQLLQRKDALLSDEVRD
                     VWYELSQGVMDIVVKLFVLAQLRALALGNERITAGLLRQVYQDELKPVHPMLEALRSG
                     IPERIARYSDLVVPEIDKRLIQLQLDIAAIQEQTPEEKALQELDTEDQRHLYLMLKED
                     YDSSLLIPTIKKAFSQNPTMTRQKLLPLVLQWLMEGETVVSELEKPSKSKKVSAIKVV
                     KPSDWDSLPDTDLRYIYSQRQPEKTMHERLKGKGVIVDMASLFKQAG"
     gene            complement(15993..18101)
                     /locus_tag="RHX21_001328"
     CDS             complement(15993..18101)
                     /locus_tag="RHX21_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000267723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HDV1986543.1"
                     /translation="MWQINEVVLFDNDPYRILAIEDGQVVWMQISADKGVPQARAELL
                     LMQYLDEGRLVRTDDPYVHLDLEEPSVDSVSFQKREEDYRKILPIINSKDRFDPKVRS
                     ELVEHVVQEHKVTKATVYKLLRRYWQRGQTPNALIPDYKNSGAPGERRSATGTAKIGR
                     AREYGKGEGTKVTPEIERLFRLTIEKHLLNQKGTKTTVAYRRFVDLFAQYFPRIPQED
                     YPTLRQFRYFYDREYPKAQRLKSRVKAGVYKKDVRPLSSTATSQALGPGSRYEIDATI
                     ADIYLVDHHDRQKIIGRPTLYIVIDVFSRMITGFYIGFENPSYVVAMQAFVNACSDKT
                     AICAQHDIEISSSDWPCVGLPDVLLADRGELMSHQVEALVSSFNVRVESAPPRRGDAK
                     GIVESTFRTLQAEFKSFAPGIVEGSRIKSHGETDYRLDASLSVFEFTQIILRTILFRN
                     NHLVMDKYDRDADFPTDLPSIPVQLWQWGMQHRTGSLRAVEQEQLRVALLPRRKVSIS
                     SFGVNLWGLYYSGSEILREGWLQRSTDIARPQHLEAAYDPVLVDTIYLFPQVGSRVFW
                     RCNLTERSRQFKGLSFWEVWDIQAQEKHNKANAKQDELTKRRELEAFIQQTIQKANKL
                     TPSTTEPKSTRIKQIKTNKKEAVTSERKKRAEHLKPSSSGDEAKVIPFNAVEADDQED
                     YSLPTYVPELFQDPPEKDES"
     gene            complement(18088..18909)
                     /locus_tag="RHX21_001329"
     CDS             complement(18088..18909)
                     /locus_tag="RHX21_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heteromeric transposase endonuclease subunit
                     TnsA"
                     /protein_id="HDV1986544.1"
                     /translation="MAKANSSFSEVQIARRIKEGRGQGHGKDYIPWLTVQEVPSSGRS
                     HRIYSHKTGRVHHLLSDLELAVFLSLEWESSVLDIREQFPLLPSDTRQIAIDSGIKHP
                     VIRGVDQVMSTDFLVDCKDGPFEQFAIQVKPAAALQDERTLEKLELERRYWQQKQIPW
                     FIFTDKEINPVVKENIEWLYSVKTEEVSAELLAQLSPLAHILQEKGDENIINVCKQVD
                     IAYDLELGKTLSEIRALTANGFIKFNIYKSFRANKCADLCISQVVNMEELRYVAN"
     gene            complement(19069..20898)
                     /gene="glmS"
                     /locus_tag="RHX21_001330"
     CDS             complement(19069..20898)
                     /gene="glmS"
                     /locus_tag="RHX21_001330"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HDV1986545.1"
                     /translation="MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMT
                     RLRRLGKVQMLAQAAEEHPLHGGTGIAHTRWATHGEPSEANAHPHVSEHIVVVHNGII
                     ENHEPLREELKARGYTFVSETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTV
                     IMDSRHPDTLLAARSGSPLVIGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRR
                     SVNIFDKTGAEVKRQDIESNLQYDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQ
                     VDLSELGPNADELLSKVEHIQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYR
                     KSAVRRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMT
                     NAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLS
                     QDKRIEALAEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPL
                     ALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMP
                     HVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLAKSVTVE"
     gene            complement(21060..22430)
                     /gene="glmU"
                     /locus_tag="RHX21_001331"
     CDS             complement(21060..22430)
                     /gene="glmU"
                     /locus_tag="RHX21_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HDV1986546.1"
                     /translation="MLNNAMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAAN
                     ELGAAHVHLVYGHGGDLLKQALKDDNLNWVLQAEQLGTGHAMQQAAPFFADDEDILML
                     YGDVPLISVETLQRLRDAKPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATD
                     EQRQIQEINTGILIANGADMKRWLAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQ
                     RLSEVEGVNNRLQLSRLERVYQSEQAEKLLLAGVMLRDPARFDLRGTLTHGRDVEIDT
                     NVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAAACTIGPFARLRP
                     GAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANK
                     FKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKEGWR
                     RPVKKK"
     gene            complement(22781..23200)
                     /gene="atpC"
                     /locus_tag="RHX21_001332"
     CDS             complement(22781..23200)
                     /gene="atpC"
                     /locus_tag="RHX21_001332"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001251972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HDV1986547.1"
                     /translation="MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLT
                     AIKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKA
                     EEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM"
     gene            complement(23221..24603)
                     /gene="atpD"
                     /locus_tag="RHX21_001333"
     CDS             complement(23221..24603)
                     /gene="atpD"
                     /locus_tag="RHX21_001333"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017800291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HDV1986548.1"
                     /translation="MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQ
                     QQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEI
                     GEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNM
                     MELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRL
                     RVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEM
                     GVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPA
                     VDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVA
                     RARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSI
                     EEAVEKAKKL"
     gene            complement(24630..25493)
                     /gene="atpG"
                     /locus_tag="RHX21_001334"
     CDS             complement(24630..25493)
                     /gene="atpG"
                     /locus_tag="RHX21_001334"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HDV1986549.1"
                     /translation="MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRP
                     YAETMRKVIGHLAHGNLEYKHPYLEDRDVKRVGYLVVSTDRGLCGGLNINLFKKLLAE
                     MKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAY
                     DEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDT
                     LLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQE
                     LTEIVSGAAAV"
     gene            complement(25544..27085)
                     /gene="atpA"
                     /locus_tag="RHX21_001335"
     CDS             complement(25544..27085)
                     /gene="atpA"
                     /locus_tag="RHX21_001335"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HDV1986550.1"
                     /translation="MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGL
                     ADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRG
                     LLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIG
                     RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGAL
                     ANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLL
                     LRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQA
                     GDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGG
                     IRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFA
                     AERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFK
                     ATQSW"
     gene            complement(27098..27631)
                     /gene="atpH"
                     /locus_tag="RHX21_001336"
     CDS             complement(27098..27631)
                     /gene="atpH"
                     /locus_tag="RHX21_001336"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HDV1986551.1"
                     /translation="MSEFITVARPYAKAAFDFAVEHQSVERWQDMLAFAAEVTKNEQM
                     AELLSGALAPETLAESFIAVCGEQLDENGQNLIRVMAENGRLNALPDVLEQFIHLRAV
                     SEATAEVDVISAAALSEQQLAKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRAGDMVI
                     DGSVRGRLERLADVLQS"
     gene            complement(27646..28116)
                     /gene="atpF"
                     /locus_tag="RHX21_001337"
     CDS             complement(27646..28116)
                     /gene="atpF"
                     /locus_tag="RHX21_001337"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HDV1986552.1"
                     /translation="MNLNATILGQAIAFVLFVLFCMKYVWPPLMAAIEKRQKEIADGL
                     ASAERAHKDLDLAKASATDQLKKAKAEAQVIIEQANKRRSQILDEAKAEAEQERTKIV
                     AQAQAEIEAERKRAREELRKQVAILAVAGAEKIIERSVDEAANSDIVDKLVAEL"
     gene            complement(28178..28417)
                     /gene="atpE"
                     /locus_tag="RHX21_001338"
     CDS             complement(28178..28417)
                     /gene="atpE"
                     /locus_tag="RHX21_001338"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HDV1986553.1"
                     /translation="MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPD
                     LIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA"
     gene            complement(28464..29279)
                     /gene="atpB"
                     /locus_tag="RHX21_001339"
     CDS             complement(28464..29279)
                     /gene="atpB"
                     /locus_tag="RHX21_001339"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HDV1986554.1"
                     /translation="MASENMTPQDYIGHHLNNLQLDLRTFSLVDPQNPPATFWTINID
                     SMFFSVVLGLLFLVLFRSVAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIA
                     PLALTIFVWVFLMNLMDLLPIDLLPYIAEHVLGLPALRVVPSADVNVTLSMALGVFIL
                     ILFYSIKMKGIGGFTKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAG
                     ELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH"
     gene            complement(29288..29668)
                     /gene="atpI"
                     /locus_tag="RHX21_001340"
     CDS             complement(29288..29668)
                     /gene="atpI"
                     /locus_tag="RHX21_001340"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418195.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit I"
                     /protein_id="HDV1986555.1"
                     /translation="MSVSLVSRNVARKLLLVQLLVVIASGLLFSLKDPFWGVSAISGG
                     LAVFLPNVLFMIFAWRHQAHTPAKGRVAWTFAFGEAFKVLAMLVLLVVALAVLKAVFL
                     PLIVTWVLVLVVQILAPAVINNKG"
     gene            complement(30285..30908)
                     /gene="rsmG"
                     /locus_tag="RHX21_001341"
     CDS             complement(30285..30908)
                     /gene="rsmG"
                     /locus_tag="RHX21_001341"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HDV1986556.1"
                     /translation="MLNKLSLLLKDAGISLTDHQKNQLIAYVNMLHKWNKAYNLTSVR
                     DPNEMLVRHILDSIVVAPYLQGERFIDVGTGPGLPGIPLSIVRPEAHFTLLDSLGKRV
                     RFLRQVQHELKLENIEPVQSRVEEFPSEPPFDGVISRAFASLNDMVSWCHHLPGEQGR
                     FYALKGQMPEDEIALLPEEYQVESVVKLQVPALDGERHLVVIKANKI"
     gene            complement(30972..32861)
                     /gene="mnmG"
                     /locus_tag="RHX21_001342"
     CDS             complement(30972..32861)
                     /gene="mnmG"
                     /locus_tag="RHX21_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HDV1986557.1"
                     /translation="MFYPDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQ
                     MSCNPAIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRV
                     LYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLD
                     GKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVGRLKTGTPPRIDARTIDFSVLAQQ
                     HGDNPMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRSNLDRSPMYAGVIEGVGPRY
                     CPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENA
                     KIVRPGYAIEYDFFDPRDLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAA
                     RLSADKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTE
                     IGRELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAEAAAEVNAHLTAPLSREAS
                     GEDLLRRPEMTYEKLTTLTPFAPALTDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNE
                     NTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGM
                     LRRSA"
     gene            complement(33240..33683)
                     /gene="mioC"
                     /locus_tag="RHX21_001343"
     CDS             complement(33240..33683)
                     /gene="mioC"
                     /locus_tag="RHX21_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein MioC"
                     /protein_id="HDV1986558.1"
                     /translation="MADITLISGSTLGGAEYVAEHLAEKLEEAGFTTETLHGPLLEDL
                     PASGIWLVISSTHGAGDIPDNLSPFYEALQEQKPDLSAVRFGAIGIGSREYDTFCGAI
                     DKLEAELKNSGAKQTGETLKINILDHDIPEDPAEEWLGSWVNLLK"
     gene            complement(33773..34231)
                     /gene="asnC"
                     /locus_tag="RHX21_001344"
     CDS             complement(33773..34231)
                     /gene="asnC"
                     /locus_tag="RHX21_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator AsnC"
                     /protein_id="HDV1986559.1"
                     /translation="MENYLIDNLDRGILEALMGNARTAYAELAKQFGVSPGTIHVRVE
                     KMKQAGIITGARIDVSPKQLGYDVGCFIGIILKSAKDYPSALAKLESLDEVTEAYYTT
                     GHYSIFIKVMCRSIDALQHVLINKIQTIDEIQSTETLIVLQNPIMRTIKP"
     gene            34383..35375
                     /gene="asnA"
                     /locus_tag="RHX21_001345"
     CDS             34383..35375
                     /gene="asnA"
                     /locus_tag="RHX21_001345"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HDV1986560.1"
                     /translation="MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGT
                     QDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPD
                     EDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSEEFGLAPF
                     LPDQIHFVHSQELLSRYPDLDAKGRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDY
                     DDWSTPSELGHAGLNGDILVWNPVLEDAFELSSMGIRVDADTLKHQLALTGDEDRLEL
                     EWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAAVRESVPSLL"
     gene            complement(35380..36831)
                     /gene="viaA"
                     /locus_tag="RHX21_001346"
     CDS             complement(35380..36831)
                     /gene="viaA"
                     /locus_tag="RHX21_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase RavA stimulator ViaA"
                     /protein_id="HDV1986561.1"
                     /translation="MLTLDTLNVMLAVSEEGLIEEMIIALLASPQLAVFFEKFPRLKA
                     AITDDVPRWREALRSRLKDARVPPELTEEVMCYQQSQLLSTPQFIVQLPQILDLLHRL
                     NSPWAEQARQLVDANSTITSALHTLFLQRWRLSLIVQATTLNQQLLEEEREQLLSEVQ
                     ERMTLSGQLEPILADNNTAAGRLWDMSAGQLKRGDYQLIVKYGEFLNEQPELKRLAEQ
                     LGRSREAKSIPRNDAQMETFRTMVREPATVPEQVDGLQQSDDILRLLPPELATLGITE
                     LEYEFYRRLVEKQLLTYRLHGESWREKVIERPVVHKDYDEQPRGPFIVCVDTSGSMGG
                     FNEQCAKAFCLALMRIALAENRRCYIMLFSTEIVRYELSGPQGIEQAIRFLSQQFRGG
                     TDLASCFRAIMERLQSREWFDADAVVISDFIAQRLPDDVTSKVKELQRVHQHRFHAVA
                     MSAHGKPGIMRIFDHIWRFDTGMRSRLLRRWRR"
     gene            complement(36825..38321)
                     /gene="ravA"
                     /locus_tag="RHX21_001347"
     CDS             complement(36825..38321)
                     /gene="ravA"
                     /locus_tag="RHX21_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418202.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase RavA"
                     /protein_id="HDV1986562.1"
                     /translation="MAHPHLLAERISRLSSSLEKGLYERSHAIRLCLLAALSGESVFL
                     LGPPGIAKSLIARRLKFAFQNARAFEYLMTRFSTPEEVFGPLSIQALKDEGRYERLTS
                     GYLPEAEIVFLDEIWKAGPAILNTLLTAINERQFRNGAHVEKIPMRLLVAASNELPEA
                     DSSLEALYDRMLIRLWLDKVQDKANFRSMLTSQQDENDNPVPDALQVTDEEYERWQKE
                     IGEITLPDHVFELIFMLRQQLDKLPDAPYVSDRRWKKAIRLLQASAFFSGRSAVAPVD
                     LILLKDCLWYDAQSLNLIQQQIDVLMTGHAWQQQGMLTRLGAIVQRHLQLQQQQSDKT
                     ALTVIRLGGIFSRRQQYQLPVNVTASTLTLLLQKPLKLHDMEVVHISFERSALEQWLS
                     KGGEIRGKLNGIGFAQKLNLEVDSAQHLVVRDVSLQGSTLALPGSSAEGLPGEIKQQL
                     EELESDWRKQHALFSEQQKCLFIPGDWLGRIEASLQDVGAQIRQAQQC"
     gene            38544..40412
                     /gene="kup"
                     /locus_tag="RHX21_001348"
     CDS             38544..40412
                     /gene="kup"
                     /locus_tag="RHX21_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low affinity potassium transporter Kup"
                     /protein_id="HDV1986563.1"
                     /translation="MSTDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGV
                     ERDAVFGFLSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSARTTSML
                     VIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVPLSIIVLTLLFMIQKH
                     GTAMVGKLFAPIMLTWFLILAGLGLRSIIANPEVLHALNPMWAVHFFLEYKTVSFIAL
                     GAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLTLNYFGQGALLLKNPEAIKNP
                     FFLLAPDWALIPLLIIAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMES
                     GQIYIPFVNWMLYVAVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARQNWHW
                     NKYFVALILIAFLCVDIPLFTANLDKLLSGGWLPLSLGTVMFIVMTTWKSERFRLLRR
                     MHEHGNSLEAMIASLEKSPPVRVPGTAVYMSRAINVIPFALMHNLKHNKVLHERVILL
                     TLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETPNVEEVFHRCGLEGLSCRMME
                     TSFFMSHESLILGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI"
     gene            40579..40998
                     /gene="rbsD"
                     /locus_tag="RHX21_001349"
     CDS             40579..40998
                     /gene="rbsD"
                     /locus_tag="RHX21_001349"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709562.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HDV1986564.1"
                     /translation="MKKGTVLNSDISSVISRLGHTDTLVVCDAGLPIPKSTTRIDMAL
                     TQGVPSFMQVLGVVTNEMQVEAAIIAEEIKQHNPQLHETLLTHLEQLQKHQGNTIEIR
                     YTTHEQFKQQTAESQAVIRSGECSPYANIILCAGVTF"
     gene            41006..42511
                     /gene="rbsA"
                     /locus_tag="RHX21_001350"
     CDS             41006..42511
                     /gene="rbsA"
                     /locus_tag="RHX21_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter ATP-binding protein RbsA"
                     /protein_id="HDV1986565.1"
                     /translation="MEALLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKS
                     TMMKVLTGIYARDAGTLLWLGKETTFTGPKSSQEAGIGIIHQELNLIPQLTIAENIFL
                     GREFVNRFGKIDWKTMYAEADKLLAKLNLRFKSDKLVGDLSIGDQQMVEIAKVLSFES
                     KVIIMDEPTDALTDTETESLFRVIRELKSQGRGIVYISHRMKEIFEICDDVTVFRDGQ
                     FIAEREVASLTEDSLIEMMVGRKLEDQYPHLDKAPGDIRLKVDNLCGPGVNDVSFTLR
                     KGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVNRSPQDGLANGIVYISE
                     DRKRDGLVLGMSVKENMSLTALRYFSRAGGSLKHADEQQAVSDFIRLFNVKTPSMEQA
                     IGLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKADGLSIIL
                     VSSEMPEVLGMSDRIIVMHEGHLSGEFTREQATQEVLMAAAVGKLNRVNQE"
     gene            42516..43481
                     /gene="rbsC"
                     /locus_tag="RHX21_001351"
     CDS             42516..43481
                     /gene="rbsC"
                     /locus_tag="RHX21_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002882531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HDV1986566.1"
                     /translation="MTTQTVSGRRYFTKAWLMEQKSLIALLVLIAIVSTLSPNFFTIN
                     NLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAASIVGIEVNALVAVA
                     AALALGAAIGAVTGVIVAKGRVQAFIATLVMMLLLRGVTMVYTNGSPVNTGFTENADL
                     FGWFGIGRPLGVPTPVWIMGIVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNK
                     IKIIVYSLCGLLASLAGIIEVARLSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIV
                     GTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLVDNKKQ"
     gene            43506..44396
                     /gene="rbsB"
                     /locus_tag="RHX21_001352"
     CDS             43506..44396
                     /gene="rbsB"
                     /locus_tag="RHX21_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter substrate-binding protein
                     RbsB"
                     /protein_id="HDV1986567.1"
                     /translation="MNMKKLATLVSAVALSATVSANAMAKDTIALVVSTLNNPFFVSL
                     KDGAQKEADKLGYNLVVLDSQNNPAKELANVQDLTVRGTKILLINPTDSDAVGNAVKM
                     ANQANIPVITLDRQATKGEVVSHIASDNVLGGKIAGDYIAKKAGEGAKVIELQGIAGT
                     SAARERGEGFQQAVAAHKFNVLASQPADFDRTKGLNVMQNLLTAHPDVQAVFAQNDEM
                     ALGALRALQTAGKSDVMVVGFDGTPDGEKAVNDGKLAATIAQLPDQIGAKGVETADKV
                     LKGEKVQAKYPVDLKLVVKQ"
     gene            44522..45451
                     /gene="rbsK"
                     /locus_tag="RHX21_001353"
     CDS             44522..45451
                     /gene="rbsK"
                     /locus_tag="RHX21_001353"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HDV1986568.1"
                     /translation="MQNAGSLVVLGSINADHILNLQSFPTPGETVTGNHYQVAFGGKG
                     ANQAVAAGRSGANIAFIACTGDDSIGESVRQQLATDNIDITPVSVIKGESTGVALIFV
                     NGEGENVIGIHAGANAALSPALVEAQRERIANASALLMQLESPLESVMAAAKIAHQNK
                     TIVALNPAPARELPDELLALVDIITPNETEAEKLTGIRVENDEDAAKAAQVLHEKGIR
                     TVLITLGSRGVWASVNGEGQRVPGFRVQAVDTIAAGDTFNGALITALLEEKPLPEAIR
                     FAHAAAAIAVTRKGAQPSVPWREEIDAFLDRQR"
     gene            45455..46447
                     /gene="rbsR"
                     /locus_tag="RHX21_001354"
     CDS             45455..46447
                     /gene="rbsR"
                     /locus_tag="RHX21_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose operon transcriptional repressor RbsR"
                     /protein_id="HDV1986569.1"
                     /translation="MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVEAAIKELN
                     YAPSALARSLKLNQTHTIGMLITASTNPFYSELVRGVERSCFERGYSLVLCNTEGDEQ
                     RMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
                     SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTG
                     DFEFNGGFDAMRQLLSHPLRPQAVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDI
                     ELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPTLQQQRLQLTPILMERGSA"
     gene            complement(46413..47840)
                     /gene="mdtD"
                     /locus_tag="RHX21_001355"
     CDS             complement(46413..47840)
                     /gene="mdtD"
                     /locus_tag="RHX21_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter subunit MdtD"
                     /protein_id="HDV1986570.1"
                     /translation="MSDKKKRSMAGLPWIAAMAFFMQALDATILNTALPAIAHSLNRS
                     PLAMQSAIISYTLTVAMLIPVSGWLADRFGTRRIFTLAVSLFTLGSLACALSNSLPQL
                     VVFRVIQGIGGAMMMPVARLALLRAYPRNELLPVLNFVAMPGLVGPILGPVLGGVLVT
                     WATWHWIFLINIPIGIAGLLYARKHMPNFTTARRRFDITGFLLFGLSLVLFSSGIELF
                     GEKIVASWIALTVIVTSIGLLLLYILHARRTPNPLISLDLFKTRTFSIGIVGNIATRL
                     GTGCVPFLMPLMLQVGFGYQAFIAGCMMAPTALGSIIAKSMVTQVLRRLGYRHTLVGI
                     TVIIGLMIAQFSLQSPAMAIWMLILPLFILGMAMSTQFTAMNTITLADLTDDNASSGN
                     SVLAVTQQLSISLGVAVSAAVLRVYEGMEGTTTVEQFHYTFITMGIITVASAAMFMLL
                     KTTDGNNLIKRQRKSKPNRVPSESE"
     gene            complement(47863..48555)
                     /locus_tag="RHX21_001356"
     CDS             complement(47863..48555)
                     /locus_tag="RHX21_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312724.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDV1986571.1"
                     /translation="MPLSAQQLAAQKNLSYVLAEKLAQRILKGEYEPGTILPGEIELG
                     EQFGVSRTAVREAVKTLTAKGMVLPRPRIGTRVMPQSNWNFLDQELLTWWMTEENFHQ
                     VIDHFLVMRICLEPQACLLAATVGTAEQKAHLNTLMAEMAALKENFRRERWIEVDMAW
                     HEHIYEMSANPFLTSFASLFHSVYHTYFTSITSDTVIKLDLHQAIVDAIIQSDGDAAF
                     KACQALLRSPDK"
BASE COUNT        12275 a        12318 c        11807 g        12406 t
ORIGIN      
        1 gtctggtgaa ttatttgtcg ctatctttcc ccgccagcag tttatccagc tcatcgccac
       61 cgacgtgacg gaaatcctgc cccttcacgt agtagaagat aaactcacaa atattctggc
      121 agcggtcgcc aatacgttcg atagaacgcg cgcagaacag cgcagtaagt acgctcggaa
      181 tggtacgcga atcttccatc atgtaggtca tcagttgacg aacaatacct tcgtattcct
      241 gatcgacttt tttatcttca cgataaatac gtaccgcttc gtcaatgtcc atccgcgcga
      301 acgcgtccag cacgtcgtgc agcatctgga tggtatgacg gcccagcgac tccagactta
      361 ccagcaacgg ctgatgctgc tgggagaatt tctccagcgc agtacggcag attttgtccg
      421 ccacgtcgcc aatacgctcc agctcggcaa tggttttact gatcaccata accagtcgca
      481 ggtcgctcgc cgtcggctga cgtttggcga taatgcgcac gcaggcttca tcgatcgcca
      541 cttccatcat gttgacgttc ttgtcgcctt cgatgacgcg cttcgccaga tcgctgtcct
      601 ggttatgcat cgcggtgatt gcatcagaaa gctgctgctc caccatgccg cccatggtca
      661 tcacctgcgt gcggatactt tccagttcgg cgttgaactg gccggaaata tgtttattaa
      721 gattgagact gtccataacg cactcctgaa tcaaccgtaa cgaccggtga tgtagtcttc
      781 tgtttgtttc ttcgctggct tggtgaacag atcgtccgtg ttgctgaact caatcaattc
      841 gcccaggtac ataaacgccg tgtggtcgga acaacgcgca gcctgctgca tgttgtgggt
      901 gacgatcacc acggtgtaat cctgcttcag ttcggtgatc agctcttcaa tacgcccggt
      961 agagataggg tcgagcgccg aacacggttc gtcgagcagc agcacttccg ggcgaatggc
     1021 gataccacgc gcaatacaca gacgctgttg ctgaccacca gagagagagt aaccgctctg
     1081 gtgcaattta tctttggttt cgttccacaa tgcggctttg gtcaatgccc actgcacgcg
     1141 ctcgtccata tcggcacggg agagcttctc aaacagacga acgccaaaag cgatgttgtc
     1201 gtagatggac atcgggaacg gcgtcggttt ctggaacacc atgcccactt tcgcacgcag
     1261 cagggcgata tcctgagagt tggtcaggat gttgtcgcca tcaagcagaa tttcaccttc
     1321 cgcacgctgc tccgggtaca gttcaaacat tttgttgaag gtacgcagca gcgtcgattt
     1381 accgcagccg gacggcccga taaacgccgt aacctggttt ttggcgatat ccaggttgat
     1441 gtttttcagg gcatggaatt tgccgtagta gaagttcaaa ttacgaacct gaattttact
     1501 cggggcagtt tcaaccatac tcattgcaat cttttcctca tcgtgcctga tgcacttcgc
     1561 taatcaggct taccgtaggc cggatcaggc gttcacgccg catccggcaa agtgttaacc
     1621 gtgtacagag tcaaaaaggc gctcggtcgg tcccctcgcc cctctgggga gagggttagg
     1681 gtgaggggaa aaccgtgtca gcaatatcaa ccgtgtttat tcttcgcaaa aacaacgcgc
     1741 gccagaatgt tcagcagcag tacgcacagg gtaatgatca ataccccggc ccaggccaat
     1801 tgctgccatt ccgcaaacgg gctcatcgca aacttaaaga tcgtcaccgg caggttggcg
     1861 atcggctgca tcatgtccgt gctccagaac tggttggaga gcgcggtaaa cagcagcggc
     1921 gcggtttcac cagcaatacg ggcaatcgcc agcaggatac cggtcataat cccggacacc
     1981 gacgctttca gcgtaatcgc agagatcatc ttccacttcg gtgtacccag cgcataagcc
     2041 gcttcacgca ggctgtccgg caccagtttc agcatgttct cggtggtgcg gataacaatc
     2101 ggcacctgca acaacgccag ggcaatcacg cccgcccagc cggagaagtg ctccatctgc
     2161 gccaccacaa tggtgtaaac aaacagacca accacaatcg acggcgcaga gagcagaatg
     2221 tcgttaatga agcgaatcac ttctgccagc caggatttac gaccatattc cgccagataa
     2281 atccccgcca taatgcccag cggcgtaccg aataccgtgg cccacaaaat taacaggccg
     2341 ctacccgcca gggcgttcgc cagaccacca ccttccgtat tgggcggcgg cgtcatttca
     2401 gtgaacagcg ccagcgacat accatcgata ccgcgagtga tggtggacat taaaatccag
     2461 atcagccaga acagaccgaa ggccatcgtc gccatcgaga gcgtcagcgc aatacggttt
     2521 ttgaggcggc gacgcgcctg cattttgcgg cgagattcag ccagcgccgc agtggtttgc
     2581 atttcaacca tagccattag cgtgccccct cattcttagc caggcgcata atcataaact
     2641 tcgatgcggc gaggacgatg aaggtaatca caaacaggat caggcccagt tccatcagtg
     2701 cggcaacgtg cagaccggat tccgcttccg caaattcgtt cgccagcgca gaggtgatac
     2761 tgttgcccgg catatacagc gaggcgctgt cgagctggta ggtgttaccg atgataaagg
     2821 tcaccgccat ggtttcaccg agcgcgcggc ccagccccag catgatgccg ccgataacac
     2881 catttttggt gaacggaaga acgatacgcc agataacttc ccaggtggtg cagccaatac
     2941 cgtaggccga ctctttcatc atcaccgggg tttgttcgaa cacatcacgc attaccgccg
     3001 caatgtacgg aataatcatg atggcgagga tcacgcctgc cgcgaggata ccgataccaa
     3061 atgcggggcc agagaacagc gcgccaacaa tcgggatatt cgacatgata ttgccgaccg
     3121 gctcctgaaa gtaaacggcg aacagcggcg caaagataaa caggccccac atgccgtaaa
     3181 cgatacttgg aatggctgcc agcagctcaa tggcgatacc cagcgggcgt ttcagccagc
     3241 caggcgcaag ctcagtcagg aacagggcga taccgaaact caccgggacg gcgatcagca
     3301 gcgcgataaa cgaagtcacc aacgtaccgt agatcggcac cagcgccccg tagatatcgt
     3361 tcggcgcatc ccactctttg gtccacagga aagccagacc aaatttctga atgctcggcc
     3421 atgaggagat gatcagagag acaataatgc cacccaacat caatagcaca atcagcgccg
     3481 ccagttttac cagcacgctg aaaattatgt cgcccttttt acccggtggg ttaaaagcag
     3541 gcttggttgc agccataagt tactcttcag ttaaacgcgt ttacaaagtc attttgtaat
     3601 gccggatgcg gcgtaaaaca ccgcacccgg cctggagttt tattagtaca gcggcttacc
     3661 gctactgtct ttaatattgg tcttccacgc agcgcgaacc tgttccacta cgctatccgg
     3721 caggctggcg taatccaggt catttgcctg tttagccccg gttttatacg cccagtcgaa
     3781 gaacttcagg acttctacac cctgctctgg tttcttctga tctttgtgga ccaaaatgaa
     3841 cgtggtagag gtaataggcc atgcatcttc gcctttctgg ttggtcagat cctgagcgaa
     3901 ggttttgctc cagtctgcac cttttgctgc attagcgaag ttttcttcag tcggcaaaac
     3961 aggtttacca tcagcggaga tcagtttggt gtacgccagg ttgttttgct tcgcataagc
     4021 atattcaacg taaccaattg cacccggcag acgctgaacg aacgcagcga taccgtcgtt
     4081 acctttacca cccagaccga tcggccattt tacggtagag ccagtaccaa cgttgttttt
     4141 ccactcttca ttcactttcg ccaggtagct ggtgaagacg aaggaagtcc cggagccatc
     4201 tgcgcggcgt actacagcaa tgttctgtga aggcagtttc agatccggat tcagtttggc
     4261 gatggcttca tcatcccact tcttgatttt gccgaggtag atgtcgccga gggttttacc
     4321 atccagcacc agctcgccag acttcaaccc tggaatgtta accgccagca ccacgccgcc
     4381 aatcacggtc gggaactgga acagaccttc ctgagccagt ttttcgtcag acagcggcgc
     4441 gtcagaggca ccaaaatcaa cggtattagc gataatctgt tttacgccac cggaagaacc
     4501 gataccctgg tagttaactt tattaccggt ttctttctgg taagtgtcag cccatttggc
     4561 atacaccggc gcagggaagg ttgcacctgc acctgtcagg cttgcttctg caaacacaga
     4621 gaaagcactc atcgataagg tcgcggcgac aacagttgcg acggtggtac gcataacttt
     4681 cataatgtct cctgggagga ttcataaagc attgtttgtt ggctacgaga agcaaaatag
     4741 gacaaacagg tgacagttat atgtaaggaa tatgacagtt ttatgacaga gagataaagt
     4801 cttcagtctg atttaaataa gcgttgatat tcagtcaatt acaaacatta ataacgaaga
     4861 gatgacagaa aaattttcat tctgtgacag agaaaaagta gccgaagatg acggtttgtc
     4921 acatggagtt ggcaggatgt ttgattaaaa acataacagg aagaaaaatg ccccgctgtg
     4981 ggcggacaaa atagttggga actgggaggg gtggaaatgg agtttttaag gattatttag
     5041 ggaagagtga caaaatagat gggaactggg tgtagcgtcg taagctaata cgaaaattaa
     5101 aaatgacaaa atagtttgga actagatttc acttatctgg ttaactaatc tagctaacct
     5161 gccgctcagc ttagtacgat cctatatcca actgatcata atcctttcat cagtatccca
     5221 aattaaatcc ccctcctaga ctgcctcacc aacactttac agtgatcccg tatttccgga
     5281 caggtgattg atttttttcg cttgtacagg tgttaagcca cagttatctt gatgtggaca
     5341 ttatgcattg taatagccca ttaacatgcg ctaagagcat aaattaatat acagtaacaa
     5401 gcattacgag gtgctaatgt ttggaaagca gcctcttcca actacaataa taagttaact
     5461 atcctccacc cacaaataat tacaaatgac ccctttccgc tataactccg atctcaccag
     5521 cggctcgcta caaacccgag agtgtcgcat tattactggc ttgttactcc aagagcttga
     5581 tgaagctgcc tgggataaag ccatgtataa ggaaaatgtg cttcagaaac gcacgcaatc
     5641 tacggtaaga cgtatttctt cagcgcttag aaaacgccta gaacacctaa gctctgactt
     5701 ttgggctttt gcgtttttat gttaggcatt gtctggcaac tggaggaagt gtaatgacca
     5761 tgaatggtca ctgtgattga cagtatcttg cttaaactta tctgaacaat ggtagaactg
     5821 gctcatattt atcccctcta tgattgttta tctttttcac cataaaaagt atcaggggct
     5881 actcagggct acataaagat atttatctac ttttactgat tgataagtag catcagtcca
     5941 tccgcaggac tggtggtgcc ggcaaaatgc tgacccaaca catgcgtata gatttgcgtg
     6001 gtcttaacat cgttatgccc taagagttct tgcacagtgc gaatatcacg ccccgcttgt
     6061 aatagatgcg tagcaaacga gtgacgaaat gtatgacaag tgacacgctt gctaacgatg
     6121 cctgcttttt gtacggctgc cttcaatgcc tttcgcgcaa cggagtcatg cagatgatgg
     6181 cggcataatt tgccgttata cgggtggttg cagagcgtgc tggagggaaa gacaaacatc
     6241 cacgccgctt gtcgataagc agaagggtat ttgtgatcta aagcaaaagg cagcgatggc
     6301 cctacgcctt gtaagttgtc gtcttgctga ataagccgcg cttgctcaat gagttatttt
     6361 attgctggga ttaggcgcgt gggcagtagg ctgtttctgc ttttcccacc cttaccgtca
     6421 tgcacagtga tgcagccatt atcaaaatca aaatctttaa cccgcaaacg caagcattca
     6481 ttaatgcgca aacctgcacc atacagcagc gtaaaaataa cttggttgcg agtatccata
     6541 acctgcaaaa tgcgttgcac ttcatttgca gagataacag agggtagccg tctaggcttg
     6601 cttgcaggga tataatcaat atcgcccaac ggctgttgta aaaacctgtt gtacaaaaaa
     6661 gctagggcat ttaaagcgat tttctgcgtg tttatggcta catgtctgct gtttgctaag
     6721 ctggataaaa acagcctgac ctcttcactg cccatggtct gaggatgacg ttttttgtga
     6781 aacagaataa aacgcttaat ccagtgcagg taagtttttt cagttttcag cgcataacct
     6841 ttttgtcgca tatccgtgcg tatagaattt aaaaatggac tgttagacat aaaacgctcc
     6901 ttgtcttgca actgtctgcc tatacagcct attctagctg ggatttaaaa aagtgcctgt
     6961 tttttacgcc tagagatgct tgtttaccgg tagagtttta atttaatgct aaataaatta
     7021 aaatgttatg agttctttgg gtgagataat gtgcatcgtg caagcaggat agacggcatg
     7081 cacgatttgt aataacagag tgtcttgtat ttttaaagaa agtctattta atacaagtga
     7141 ttatattaat taacggtaag catcagcggg tgacaaaacg agcatgctta ctaataaaat
     7201 gttaacctct gaggaagaat tgtgaaacta tcactaatgg tagctatatc gaagaatgga
     7261 gttatcggga atggccctga tattccatgg agtgccaaag gtgaacagct cctgtttaaa
     7321 gctattacct ataaccaatg gctgttggtt ggacgcaaga cttttgaatc aatgggagca
     7381 ttacccaacc gaaagtatgc ggtcgtaaca cgttcaagtt ttacatctga caatgagaac
     7441 gtattgatct ttccatcaat taaagatgct ttaaccaacc taaagaaaat aacggatcat
     7501 gtcattgttt caggtggtgg ggagatatac aaaagcctga tcgatcaagt agatacacta
     7561 catatatcta caatagacat cgagccggaa ggtgatgttt actttcctga aatccccagc
     7621 aattttaggc cagtttttac ccaagacttc gcctctaaca taaattatag ttaccaaatc
     7681 tggcaaaagg gttaacaagt ggcagcaacg gattcgcaaa cctgtcacgc cttttgtacc
     7741 aaaagccgcg ccaggtttgc gatccgctgt gccaggcgtt aggcgtcata tgaagatttc
     7801 ggtgatccct gagcaggtgg cggaaacatt ggatgctgag aaccatttca ttgttcgtga
     7861 agtgttcgat gtgcacctat ccgaccaagg ctttgaacta tctaccagaa gtgtgagccc
     7921 ctaccggaag gattacatct cggatgatga ctctgatgaa gactctgctt gctatggcgc
     7981 attcatcgac caagagcttg tcgggaagat tgaactcaac tcaacatgga acgatctagc
     8041 ctctatcgaa cacattgttg tgtcgcacac gcaccgaggc aaaggagtcg cgcacagtct
     8101 catcgaattt gcgaaaaagt gggcactaag cagacagctc cttggcatac gattagagac
     8161 acaaacgaac aatgtacctg cctgcaattt gtacgcaaaa tgtggcttta ctctcggcgg
     8221 cattgacctg ttcacgtata aaactagacc tcaagtctcg aacgaaacag cgatgtactg
     8281 gtactggttc tcgggagcac aggatgacgc ctaacaattc attcaagccg acaccgcttc
     8341 gcggcgcggc ttaattcagg agttaaacat catgagggaa gcggtgatcg ccgaagtatc
     8401 gactcaacta tcagaggtag ttggcgtcat cgagcgccat ctcgaaccga cgttgctggc
     8461 cgtacatttg tacggctccg cagtggatgg cggcctgaag ccacacagtg atattgattt
     8521 gctggttacg gtgaccgtaa ggcttgatga aacaacgcgg cgagctttga tcaacgacct
     8581 tttggaaact tcggcttccc ctggagagag cgagattctc cgcgctgtag aagtcaccat
     8641 tgttgtgcac gacgacatca ttccgtggcg ttatccagct aagcgcgaac tgcaatttgg
     8701 agaatggcag cgcaatgaca ttcttgcagg tatcttcgag ccagccacga tcgacattga
     8761 tctggctatc ttgctgacaa aagcaagaga acatagcgtt gccttggtag gtccagcggc
     8821 ggaggaactc tttgatccgg ttcctgaaca ggatctattt gaggcgctaa atgaaacctt
     8881 aacgctatgg aactcgccgc ccgactgggc tggcgatgag cgaaatgtag tgcttacgtt
     8941 gtcccgcatt tggtacagcg cagtaaccgg caaaatcgcg ccgaaggatg tcgctgccga
     9001 ctgggcaatg gagcgcctgc cggcccagta tcagcccgtc atacttgaag ctaggcaggc
     9061 ttatcttgga caagaagatc gcttggcctc gcgcgcagat cagttggaag aatttgttca
     9121 ctacgtgaaa ggcgagatca ccaaggtagt cggcaaataa tgtctaacaa ttcgttcaag
     9181 ccgacgccgc ttcgcggcgc ggcttaactc aagcgttaga gagctgggga agactatgcg
     9241 cgatctgttg aaggtggttc taagcctcgt acttgcgatg gcatcggggc aggcacttgc
     9301 tgacctgcca attgttttag tggatgaagc tcgtcttccc tatgactact ccccatccaa
     9361 ctacgacatt tctccaagca actacgacaa ctccataagc aattacgaca atagtccatc
     9421 aaattacgac aactctgaga gcaactacga taatagttca tccaattacg acaatagtcg
     9481 caacggaaat cgtaggctta tatatagcgc aaatgggtct cgcactttcg ccggctacta
     9541 cgtcattgcc aacaatggga caacgaactt cttttccaca tctggcaaaa ggatgttcta
     9601 caccccaaaa ggggggcgcg gcgtctatgg cggcaaagat gggagcttct gcggggcatt
     9661 ggtcgtcata aatggccaat tttcgcttgc cctgacagat aacggcctga agatcatgta
     9721 tctaagcaac tagcctgctc tctaataaaa tgttaggcct caacatctag tcgcaagctg
     9781 aggggaacca ctagtgtcat acgaacctcc aagagacggt tacacaaacg ggtacattgt
     9841 tgatgtcatg tatgacaatc gcccaagtaa gtatccagct gtgttcagaa cgtacgtccg
     9901 aattccagac tatgtcgaac tagataacgc ggaggagctg gccgacgcaa tcattcgaga
     9961 ggttgagtta aaggaggcat ggctcacaag ggtcttgggg aactcagccg atcctgacgc
    10021 ttctgtgggc aagtgggacc ggcgcctagc gcagtgcggt ggtattgatg agatgtcaag
    10081 tggggtgcag gcaacatact tcagtccaaa cggtcagctg gtcggcttag tggcatacat
    10141 tgatgccgaa tggatggatg aatagctctg acgttacgat tcaggtgaga caaccagatg
    10201 ggcattgcgt acaagctcag ttgccaccga tgtggctacg agtctgatct tctttaccta
    10261 ggccaaggta tggcgatgct tcctgagcaa atagtcggaa cgtgcacatg ctgcgacaat
    10321 ctaacgacga tttctataaa tgaaagctac ggagtatgct cactttgtgg ggctaaggat
    10381 cgtgtgatat ttacaagcta tcagcatgag gcaaggccaa gaaatccctg ctatctagag
    10441 agaagtttca aatatcaatg cccaagatgc catgccttca gtatggagcc tccggatcta
    10501 ccggagatgc tttgggacta atgctccgct ttgcctcggg tatccgttcg acctatgttt
    10561 aagaggaaac gcacgtgtct gccgccaaag ctcttgccta tgcactttgt gacaagttgg
    10621 aaagcaaaaa agttgatgaa gtcgtacgaa atcttgtttc tagcggctgg aatattaggg
    10681 aagtggcctg ggaagcttcg tcctttgatc atgaaatgcc ctactttgac acggggcggg
    10741 acttcgatat tggatttcct gacacgctgt catccaagat tgagtttttg accgcgaatg
    10801 gatcaatcgt ccaagcacgt gctcgcctgc acttcaagca ggctctaatt tttgccaagg
    10861 cgtccaaaca tgtcgccgcg ctcaagaact cattggatta ctactatgga tcgtctgtaa
    10921 tcccccctca aaaccacgga ggctatttgt agaaaattcc attaatatga actcaaggtg
    10981 ttccctacgg acgaatcagc gatgaaggtg gtgtacctgg ctatccaggc ggcgaccaag
    11041 aaatggacga tgccgatccg caactggaag ccggccatga accgttttat gatcgaattt
    11101 ggtgaccgtt taaatggcca cctttaactg accggcaaaa gcacttacac aaaagggttt
    11161 acaggctctt tcagtcattc ctttaatgcg taaattgctc tctaaccact ctctcagccc
    11221 acccttccat atcctctctc gatacttgca gctcccccaa cccctttgga tgattcaccc
    11281 ctctatgccc gtcttgtcca tataattgat caaacaaact atttggccaa ttcaatgagc
    11341 tcttcaccac tccacgccgt atcttttcaa aatcattccg ccatgtttcg ctatcaacgc
    11401 cactcaacac tttggtagaa agcattttca ccccatccga tgcatccacc tctagcaata
    11461 caaattcact gccattacgt tgcaccccaa cggctttaat cactcttggt gagccatctt
    11521 tacacagatg taatcggcta cgcccaactt ttggcaaaac caaggtttct tcaaaaagca
    11581 cccgacatgc aaatttagtt tttagaattg aaagtagctc atcaaaagca gcaaatcgat
    11641 tagcaaaaat agagttgtaa ttggttgcat cctgcttccc acccacatct gccgctgcta
    11701 ggacaccacc taagtgtggc tcatcagtac taaccaaatt actattttca cttgttgttg
    11761 cttcttcttt ttctaaaata gtttggctac tttttcttgc cctgcgagat ttttcaattc
    11821 gactaggtct actaaaactt atccatgtcg gctcagcctc tatgactcgt gtgtctgtgt
    11881 ctatattggc tgtttcctca tcgtccaact gtagatgctc atcatcaaca actgactctg
    11941 ttgaaaccgc tatgtgctgc gtactaccat cacctgcctc cttttcctga aaagaggcat
    12001 ggctaatagc tgttgtgcta ggaagcatag cgttgatttc taaacctact atttcctcaa
    12061 ctaaataatc cttatcctcg ttagaagaac gtccttttac atgtaatttc caaccctgca
    12121 tgggcggagg gtcaaagcta aagcaccagc tttcaacgcc gttcttaatt tctctatttt
    12181 gttgatagtg cctaaaaata ctttcatacg aatccataac atcttgatcc gaaaacaacc
    12241 aaaccaaaag ctgcactacg gccgactgct ctaacgcccc tttaggaaac gatgaactgg
    12301 gtaagatcct tatctctaaa tgatctcgct caacctcata ctgaacgtcg aactcttgct
    12361 gtaaagcggt actgctcaaa cagcttcgac agaaatagga gttaattaaa aataatgacc
    12421 gagctagctc taactgtggg atgtgataac gagtcttgct atatggtgtt tcagcttcgt
    12481 aaataaatga actctgcgct ccatccttgt tgcgtacgga agcaaaggac gagagattag
    12541 gaaaatcgat tattttggct cgttgaagat ccgatgcttc aaactcaatc acacgatccg
    12601 ccttatttat ttgctttgtt gtactgttaa ccaccttagc tcgacttaat aaaggcaaat
    12661 gagtaaatcg agtccatttc cgttcttgca ttggattaaa ccaaacaaaa atacgccact
    12721 ccttatgacc cgagttacgg aataaatgac caatatgtac aacctgcaca ttgtcattaa
    12781 atgtagctag cctaaccact cactcttccc cataaaccat ttccaagaat ctttgtgctt
    12841 cctcagttat ccgctcttta gataacgttg cacttcttaa taatcgccag cgcctaagct
    12901 caacatcttc ctgtttaagc ttaataaaag cttggctaat ccgtctaatt tgataatctt
    12961 ccacactctc tgagtaacgc tttaagcaaa gcgctaccaa aggcagtttc tgtagatttt
    13021 ttgcaagaga ggttccgtta ggagtttgct ttaacagcca gctcgatgtc gctcttgggt
    13081 gatcaaggct actatctaga cgctttatga ttcttaatag ttgtcgtaca gcaattcgat
    13141 ctctttggtt ccaatcaact ctaggggcgg gtgccagacg ctcttgttga tgctgttgat
    13201 tccagtgaac tagccaatcc ctgtcatgtc ggtaaagcca agcgtatagc accccaccct
    13261 ctaaagactg tcttgccgcc ttaattcctt ggtatttatg cactagttgc tgccagtctt
    13321 tatgcttaac agataaatct tcagagttag gttgcacaga ctggctaaca ggtcttgtcg
    13381 ttatagagtg ctcagtaaga gcacttgcct gctgtagcgc ttctataacc gttagttttg
    13441 gcaataaggc ttgccacaca atactatgct gtaaataact aaaggctttt ctatgcttac
    13501 ggaatatact tttcagccaa cacgtgtcct tgttctctgc caactttaaa tccagtttct
    13561 ctagtgcctc atcactaaaa gtctgcctca ctctctccgc caccaagtca tgacgaatgt
    13621 gcttgctttt ggttagccct agatcctgcg ctaagcgctg ataaaacagc gtccactgct
    13681 caaggcttgg ggaaagctct tgcgctcgtg gagcatctaa cagaggggct atataagcag
    13741 ctagtgctgt taattgagat agggagtctt tggggtagtc tgaaagcagc tcagtatgac
    13801 ccaaagccca aaattgatgt cggtgatcat ctacagctct atcaaagaag actaaagcac
    13861 cgtgttttgg acaatatggc aaagcgggca aataccaatc tcgttgccaa aaggcttccc
    13921 catacctatt tagctgaaga gcaacgcaat cagggcagta tctaaagcgg ttatcgctct
    13981 taactctaga agcagcgact cctagcatta aatgcaccgc accttgcgct tggtactcca
    14041 ttaaccgaat agcttcgtct cggcgctcct tgcctacaaa cggagcatat aaagggaata
    14101 aggtatgctc ataaataagc tgctgaacag cgtaacgtcc tgtttgatgt agatgtcttg
    14161 ctatcacacc taaatgcgag ggcagaccta aggtagcgac caccttgcgg ttgccataca
    14221 cctcatccaa cagctgctta ggactaacaa tcccttgata aacgcctgcc cgtgcaatag
    14281 tgctataaat cagctcattc gagtacggaa caggaaagtt tctcatggct aacctgcttg
    14341 tttaaataag ctcgccatat ccactattac ccctttccct tttaaccgtt catgcatggt
    14401 tttttcaggt tggcgttgtg aatagatata acgtaaatcc gtatcaggca agctatccca
    14461 gtcgctgggc ttgactacct ttatagccga aaccttttta ctcttggagg gcttttctag
    14521 ttctgacact accgtttcgc cttccatcaa ccactgcaaa acaagaggca gtaacttttg
    14581 tcttgtcatc gttggattct ggctaaacgc ttttttaata gtgggaatta acaggcttga
    14641 atcgtaatcc tctttcagca tcagatataa atgacgctga tcttcggtat ctaactcttg
    14701 aagggctttt tcttctggtg tttgttcttg tatcgctgcg atatctagct gaagttggat
    14761 taaccgttta tcaatctcgg gaacgactag atcagaataa cgagcaatgc gttctgggat
    14821 acccgagcgt aatgcctcta gcatggggtg cacaggcttt aactcatctt gatacacttg
    14881 ccgcaataaa ccagcggtaa tacgctcatt gcctaaagct agcgcacgga gctgagcgag
    14941 tacaaaaagt tttactacaa tgtccatcac tccttggctt agctcatacc acacatcacg
    15001 gacctcatcc gataacagcg catctttgcg ttgtaaaagc tgtaattgcc aaagattatc
    15061 cgtaaaagcg atccactctt gattgggctt tccacgttgc gtttgttgta taggatccca
    15121 gaatatagct ccaaaccctg cccctctacg tgcagaccgc aaatcagcct caaaaatctc
    15181 tcgtgcttta ggggtaccaa tcaacatcac tggtacgcca ataatattca ccatcgtcac
    15241 aaaaaagttc agcatctctt gagatccacc cgaacgagag cggcttaaat gctgaatttc
    15301 atcaataacc aacaacccta aagcatgtgc attggctatt tgcgacatca aagccaacat
    15361 ggtttctata ccatgacgtt ttaagccata acgacgctca tagttcgagc ccaaggctcg
    15421 atccaacgct ctgaaaaaat tcaagcagat ttcttttagc gaaccattat gcgagcagtc
    15481 tattttcaaa tacaccacct gctctacatt gagttcacga tggtaaatca cctgaggata
    15541 cgtggctaga atacgatgaa gagaggtcgt cttcccacta ccagaacaac caattaacaa
    15601 taagctttgt gccgtagatc gtgcctcctc aaagcgaaat gtctccaact ctcccgtttg
    15661 aacacgctca taaccatttt gtaaatgctt ttgtaaatct cctgttttag gatttctgcc
    15721 tacgtagcca cctcgaatca tgaccgaaat acgctcactt agtagcaaat gcgtacctaa
    15781 tggctgaaaa tagtcatctg gaatacgaca aatggtatga gctctgataa cacgggactt
    15841 ttgcaagtca gaggaagtaa gctgtaaaga ggatttcagt gatgcagcac tattcactga
    15901 ctcttgtaat ggtggtaagg cctcgataaa aggattatca cgataagcct ctacccccgt
    15961 atcacgataa actgcttgaa tccgggtagc actcatgact catccttttc tggtggatcc
    16021 tgaaataatt caggcacgta tgtgggtagg ctgtaatctt cttgatcatc cgcttccact
    16081 gcgttgaaag gaataacttt agcctcatca cctgaagagc ttggcttcaa atgctccgca
    16141 cgttttttac gctccgaggt cacggcttct tttttattag ttttaatctg cttaatgcgt
    16201 gttgatttgg gctcagtagt actgggcgtt aacttattcg ctttctgaat ggtttgctga
    16261 ataaacgcct caagctccct gcgtttagtt aactcatcct gcttcgcatt ggctttattg
    16321 tgtttttctt gtgcttgtat atcccaaacc tcccaaaatg agagaccttt aaactgccga
    16381 ctacgttccg tcagattaca gcgccaaaat acacggctgc caacttgcgg aaacaaataa
    16441 atcgtatcaa ccagcactgg gtcataagcc gcttctaaat gttgaggtct agctatatca
    16501 gtgctccgct gcaaccaacc ctcacgcaga atctctgacc ccgagtaata caaaccccac
    16561 aaattaacgc caaatgaaga aatagagacc tttcggcgag gcagtaacgc tactcgcaac
    16621 tgctcttgct ccacagccct taaactacct gtacgatgct gcatacccca ttgccatagc
    16681 tggacaggaa tagacggtaa atctgtagga aaatcagcat ctcgatcgta tttatccatc
    16741 accagatggt tatttctgaa taagatcgta cgcaaaataa tttgtgtgaa ctcaaatacc
    16801 gacagagatg catctaacct atagtctgtt tcaccatggc ttttgatccg actgccctct
    16861 acaatgccag gtgcaaagga cttaaactcg gcttgtagtg ttctaaaagt gctttccact
    16921 atgcctttag catcgccacg tctaggtgga gcactttcca ctcgcacatt aaaactagaa
    16981 actaaggctt cgacctgatg actcattaat tcgccacggt ccgctagcaa cacatctggc
    17041 aaacctacac acggccagtc tgagctacta atctcaatat catgctgggc acaaatggcc
    17101 gttttgtcag agcaagcatt tacaaaagcc tgcatcgcca ccacataaga cggattttca
    17161 aagccgatat aaaagcccgt gatcatccga ctaaacacat caatcacaat gtaaagcgtt
    17221 ggtcttccta tgattttttg gcgatcatga tgatccacta aataaatatc agcaatcgtg
    17281 gcatcaatct cataacgact cccagggcct aacgcctgag aagtggctgt actacttaag
    17341 ggtcgtacgt cttttttata tacccctgct ttaactctag actttaagcg ctgagcttta
    17401 gggtattctc gatcataaaa ataacgaaac tgacgtagtg ttgggtaatc ctcttgggga
    17461 atgcgaggaa aatactgagc aaacaagtcc acaaatcgtc tataggcaac ggtggtcttt
    17521 gtaccttttt gatttaacag gtgcttttct atggtcaacc taaaaaggcg ttcaatctcg
    17581 ggcgttacct tggttccttc acccttacca tattctctgg ctcggccaat ctttgctgtt
    17641 cctgtcgctg aacgtctttc ccctggtgca ccgctgtttt tgtagtcagg aattaatgca
    17701 ttaggcgttt gaccacgctg ccagtaacgg cgtaacaact tataaactgt agccttagta
    17761 accttatgtt cttggaccac atgctcaacg agttcgcttc tgactttagg gtcgaaacga
    17821 tccttactat taataatagg aagaattttt cgataatcct cctcgcgctt ctggaagctg
    17881 acagaatcta cagacggctc ttctaaatca agatgtacat aagggtcatc agttctaact
    17941 aagcggcctt catctaaata ctgcattagc aacaactcag ccctagcttg tggaactcct
    18001 ttatcagcgc ttatttgcat ccagacaact tggccatcct ctatagccaa aatgcgatac
    18061 ggatcattat caaatagcac aacctcatta atttgccaca tagcgcaact cctccatatt
    18121 cactacttgg ctaatacaga gatctgcaca cttatttgcc ctgaaagact tataaatatt
    18181 gaacttaata aaaccatttg cggttaaggc tcgtatctca ctcaatgttt tgcctaactc
    18241 caaatcataa gcaatatcaa cctgcttaca gacattgata atgttttcat ctcctttttc
    18301 ttgcaggata tgggccaatg gggatagttg tgctaaaagc tccgcagaaa cttcttctgt
    18361 tttcactgaa taaagccatt caatattttc ttttactacg ggatttattt ctttatcagt
    18421 aaaaatgaac caaggaattt gcttttgctg ccaatagcga cgctctagtt ctagtttttc
    18481 taaggtacgc tcgtcttgta aggctgctgc aggtttgact tgaatagcaa actgctcaaa
    18541 aggaccatct ttgcagtcca ctaaaaaatc agtagacata acctgatcta caccacgaat
    18601 aacaggatgc ttaataccac tatctattgc aatctgcctg gtatcactag gtaataaggg
    18661 gaactgctcg cgtatatcta gcacgctgct ctcccactca agactgagaa aaacagcaag
    18721 ctctaagtca gatagcaaat gatggactcg tcccgtctta tgagaataaa tacggtggga
    18781 acgacctgaa gaaggaactt cttgtactgt tagccatgga atatagtctt taccatgccc
    18841 ttggccacgc ccctctttaa tacgacgggc aatttgcact tcagaaaatg aagagtttgc
    18901 tttagccata acaaaagtcc agtatgcttt ttcacagcat aactggactg atttcagttt
    18961 acaactattc tgtctagttt aagactttat tgtcatagtt tagatctatt ttgttcagtt
    19021 taagacttta ttgtccgccc acacccgctt acgcagggca tccatttatt actcaaccgt
    19081 aaccgatttt gccaggttac gcggctggtc aacgtcggta cctttgatca gcgcgacgtg
    19141 ataagccagt agctgcagcg gaacggtgta gaagattggt gcaatcacct cttccacatg
    19201 cggcatctcg atgatgtgca tgttatcgct acttacaaaa cccgcatcct gatcggcgaa
    19261 gacatacaac tgaccgccac gcgcgcgaac ttcttcaatg ttggatttta gtttttccag
    19321 caattcgttg ttcggtgcaa cgacgataac cggcatatcg gcatcaatca gcgccagcgg
    19381 accgtgtttc agttcacctg cagcgtaggc ttcagcgtga atgtaagaga tctctttcag
    19441 cttcaatgcg ccttccagcg cgattgggta ctgatcgcca cggcccagga acagcgcgtg
    19501 atgtttgtca gagaaatctt ctgccagagc ttcaatgcgt ttgtcctgag acagcatctg
    19561 ctcaatacgg ctcggcagcg cctgcagacc atgcacaatg tcatgttcaa tggaggcatc
    19621 cagacctttc aggcgagaca gcttcgccac cagcatcaac agcacagtta actgagtggt
    19681 gaatgcttta gtggatgcca cgccgatttc tgtaccggcg ttggtcatca gcgccagatc
    19741 ggattcgcgc accagagaag aacccggaac gttacagatt gccagcgaac caaggtaacc
    19801 cagctctttc gacagacgca ggcccgccag ggtatccgcg gtttcgccag actgtgacaa
    19861 ggtgatcatc aggctgttac gacgcacggc agatttacga tagcggaatt cagaggcgat
    19921 ttcgacgtcg cacggaatac ctgccagcga ttcaaaccag tagcgggaaa ccataccgga
    19981 gttataagaa gtaccacagg cgaggatctg aatatgctca accttcgaca gcagttcgtc
    20041 ggcgttcggt cccagctcgc ttaaatcaac ctgaccgtgg ctgatgcgcc cggtaagggt
    20101 gttttttatc gcgttcggct gttcgtagat ctctttctgc atgtagtgac ggtaaatacc
    20161 tttatcgccc gcgtcatatt gcagattgga ttcgatatcc tgacgtttta cttccgcgcc
    20221 agttttatcg aagatgttta ccgaacggcg agtaatttcc gcaatatcgc cctcttcaag
    20281 gaagataaag cgacgggtca ccggcaacag cgccagctgg tcagaagcga taaagttttc
    20341 gcccataccc aggccaatca ccagcggact accagaacgt gccgccagca gggtatccgg
    20401 gtgacgggag tccatgatca ctgtaccgta cgcaccgcgc agctgcggga tagcacgcag
    20461 aacagcctca cgcagagtcc cgccttgttt cagctcccag ttcaccagat gggcaattac
    20521 ttcggtgtct gtttcagaaa cgaaggtata gccacgcgct tttaactctt cacgcagcgg
    20581 ttcatggttt tcgatgatgc cgttatgcac caccacaatg tgttcagaaa catgcggatg
    20641 cgcgttagct tctgaaggtt caccgtgggt cgcccagcga gtgtgagcaa taccggtgcc
    20701 gccatgcaga ggatgttctt ccgctgcctg agccagcatc tggactttac cgaggcgacg
    20761 caggcgggtc atatgacctt ccgcatcaac aacggccaga ccggcagagt catatccgcg
    20821 gtattccaga cgacgtaaac cttcaagaag gatttctgct acatcacgtt gcgcgatcgc
    20881 gccaacaatt ccacacatag tttttgattc cgatttatat cgttgtcggt caacctgtat
    20941 gcccgttttt tcgggcgccc cgagccttgt agagagtggg gttattttta tagttactgc
    21001 ttgtgggagg gagattatgt tatctcctca tcccagatga ccggattacc cggccagaat
    21061 tactttttct ttaccggacg acgccagcct tctttctgag tctgcggcac acggctgata
    21121 gctaatgcat tttcgccgac attacgcgtc acagttgtac ccgcagcaat ggtcgcgcct
    21181 ttgcctactg ttaccggggc caccagctga gtgtcggaac cgacaaacac atcgtcgccg
    21241 ataatggtct taaatttatt cgcaccatcg tagttgcagg taattgttcc cgcgccgatg
    21301 ttaacgttat cgccaatttc cgcatcgccc aggtaagtca gatgcccggc tttcgagcct
    21361 ttacccagac gcgctttttt catctcaacg aagttaccaa cgtgtgcacc ttccagcaac
    21421 tcagcaccag gacgcagacg ggcaaacggg ccaatagtac aggccgctgc cagattcgcg
    21481 tcttccacaa cggtatacgg actgatttcg caatcatcgc caatcacgct gtttttaatc
    21541 acgcaaccgg tgccgatttt cacgcgatga ccgagagtca cgttgccctc gatgataacg
    21601 ttagtatcaa tttcaacatc gcgcccgtga gtaagcgtac cgcgcagatc aaaacgcgcc
    21661 ggatcgcgca gcataacgcc tgctaacagc agtttttcag cctgttcgga ctggtaaacg
    21721 cgctccagac gggagagttg caggcggtta ttcacacctt ctacttcgct taaacgttgc
    21781 ggatgaacgg cgacgatttc acgcccttcc tgatacgcca gcgcaataat gtcggtgatg
    21841 tagtattcgc cctgagcatt attgttggtc agcttcgcca gccagcgttt catatctgcg
    21901 ccgttagcga tcagaatgcc ggtgttgatc tcctgaatct gacgctgctc gtcggtggca
    21961 tctttgtgct caacaatgcc ggtaactttg ccattttcac gggtgatacg tccataaccg
    22021 gtcggatcat ccagtttcac cgtcagcaga ccaatgccac cctgcggttt agcatcacgc
    22081 aggcgctgga gtgtttcgac agagatcagc ggcacgtcgc cgtagagcat taaaatgtct
    22141 tcatcatcgg caaagaaagg tgcggcctgc tgcattgcat gacccgtacc cagctgctct
    22201 gcctgaagca cccagttaag gttgtcgtct ttcagcgcct gtttaagcag atcgccgccg
    22261 tgaccgtaca ccaggtgaac gtgcgctgcg cctaattcat tcgcagcatc aatgacatgc
    22321 tgaaccatcg ctttcccggc aagggtatgc agcactttcg gaagatcgga atacatgcgc
    22381 gtgcctttgc ctgcggcaag gatcactacg ctcatagcat tattcaacat acgcgtcctg
    22441 actgtaattt gagaacgaat ttaaaccgct tcaccttgaa aaaactacat ttttttcatc
    22501 gtgaaatgga cagaggataa attgttcaat aacggattat ccccgctgac gaaagtgcca
    22561 ttttcgacca tcgtcacgcc ttttgtctgc agaaaattaa ggcagtacct tcatttaagc
    22621 gtcaggtgga tgtttttgct cttatttcga tcaatgaata aacgggaaaa caggggtgtt
    22681 ttatatcagc aggatctatg tgaacgctct tcaggacgga tcacgcgtaa aaaaaagcca
    22741 gcctgtttcc agactggctt ttgtgctttt caagccggtg ttacatcgct tttttggtca
    22801 actcgataac gcgcagctgc gcgatcgctt tggccagttc cgcagacgcc tgagcgtaat
    22861 ctacgtcgcc gtgagagctg ctaatgtgct cttcagcctt acgtttcgct tccatggctc
    22921 gcgcttcgtc gagatcctgg ccgcgaattg cggtgtcggc cagaacggtc acgttgccag
    22981 gctgcacttc aagaatgccg ccagacagat agataaactc ttcgtgaccg tgctgtttca
    23041 cgatgcgaat cataccaggc ttaatggcgg tgagcagcgg tgcgtggcca gggtagatcc
    23101 ccagttcacc ttcgctaccc gttacctgga ttttctcgac cagaccagag aacatttgtt
    23161 gctctgcgct gacgacgtcc aggtggtaag tcattgccat atcaccctcc gattaaggcg
    23221 ttaaagtttt ttggcttttt ccacagcttc ttcgatggaa ccgaccatgt agaacgcctg
    23281 ctccggcagg tgatcgtatt cgccttccat gatgccttta aagccacgga tggtgtcttt
    23341 cagggagacg tatttacccg gagaaccggt gaatacttct gccacgaaga acggctggga
    23401 caggaagcgc tggatcttac gagcacgcgc taccaccagt ttgtcttctt cagacagttc
    23461 atccataccc aggatggcga tgatgtcttt cagttcctga taacgttgca ggatggactg
    23521 aacgccacgc gcggtgtcgt agtgttcctg accaaccacc agcgggtcca gctgacggct
    23581 ggtggagtcc agcgggtcaa cggccgggta gatacccaga gacgcgatct gacggctcag
    23641 taccacggtt gcgtcaaggt gcgcaaaggt ggttgccgga gacgggtcag tcaagtcatc
    23701 cgcaggtacg tatactgcct gtacggaggt gatagaacca gttttggtgg aggtgatacg
    23761 ttcctgcaga acgcccatct cttccgccag ggtcggctga taacctaccg ctgaaggcat
    23821 acggcccagc agtgcggata cttccgtacc ggccagggtg taacgataga tgttgtcaac
    23881 gaacagcaga acgtcacgac cttcgtcacg gaatttctca gccatggtca gaccggtcag
    23941 agcaacgcgc agacggtttc ccggcggctc gttcatctgg ccatacacca gggatacttt
    24001 gtcgataacg ttggagtcgg tcatttcgtg gtagaagtcg ttaccctcac gagtacgttc
    24061 acctacgccc gcaaacacag agtaaccgga gtgctcgatc gcgatgttac gaatgagctc
    24121 catcatgttt acggttttac ctacacccgc accaccgaac agaccaactt taccgccctt
    24181 agcgaacgga cacatcaggt cgataacttt gataccggtt tccagcagtt cctgagagtt
    24241 tgacagctct tcgtaggaag gtgctgcgcg gtgaatcgcc caacgctctt cttcaccgat
    24301 ctcgcctttc atgtcgaccg gttcacccag tacgttcatg atacggccca gagtcgcttt
    24361 acctaccggg acttcaatcg ggtgttcgag gtcttttaca tccagaccgc gacgcagacc
    24421 gtcggaggaa cccattgcga tggtacgtac gataccgccg ccgagctgct gctgaacttc
    24481 cagcaccaga cgctcattac cattttgcac ctcaagagca tcgtacacgc gcggtacggc
    24541 atcctgaggg aattcgacgt caactacggc gccgattacc tggacaatct ttccagtagc
    24601 catcttaaat cctctacgaa ataacctgtt taaaccgcgg cggcccccga gacgatctcg
    24661 gtgagttcct gagtaatgct ggcctgacga gctttgttgt ataccaactg cagctcttta
    24721 atcaggctgc cgccattgtc ggtcgcggct ttcatcgcca ccatacgggc ggcctgctcg
    24781 ctggccaggt tttcaaccac gccctgataa acctgagatt cgacataacg acgcagcagg
    24841 gtatccagca acgccttcgg atcgggttcg tacaggtaat cccaggattt atgtttcaga
    24901 tcatcatcat ctgatgccgg taacggcagc agctggctga tggtcggaac ctgagacatg
    24961 gtgttaataa atttgttgct gacaatgtaa agcttgtcca gacggccttc gtcgtaggcc
    25021 tgcaacatca cttttaccgg accgatcagt tcggacaggg aagggttatc ccccatgccg
    25081 gtgacctggg caacaacatt gccgcccacg gagttgaaga acgacacgcc tttcgagccg
    25141 atcattgcga ggtcgcattg aacgcctttg tcggtccagg tcttcatttc cgccagcagt
    25201 tttttgaaca ggttaatgtt caaaccaccg cacaaaccac ggtcggtcga caccaccagg
    25261 tagcccacgc gtttaacgtc gcggtcttcc aggtaagggt gcttatattc cagattaccg
    25321 tgtgcaaggt gaccaatcac tttgcgcatg gtttctgcat aaggacggct ggccgccatg
    25381 cgatcctgcg atttacgcat tttggaagcg gcgaccatct ccatcgcttt agtgatcttt
    25441 tgcgtgttct ggacgcttgc gatcttacta cgtatctctt ttgcgccggc catgagcttc
    25501 tcctcaatgc cttgcggcct gccctaaggc aagccgccag acgttaccag gattgggttg
    25561 ctttgaagga atcgaggatg cctttcagct tgccttcgat ttcgtcgttg tagccaccgg
    25621 tctggttgat ctcttgcatc aacggagcgt gatcacggtc gacgtaagcc agcagagcgg
    25681 cttcgaagct gccaattttc gacagttcaa catccgccag gtaaccacgt tctgctgcga
    25741 acagaaccag agactgctgc gcaacggaca tcggcgcata ctgtttctgt ttcagcagtt
    25801 cggtcacttt ctgaccgtgg tcaagctgct tacgtgttgc atcgtcaagg tcggatgcaa
    25861 actgagagaa cgctgccagt tcacgatact gtgccagagc ggtacggata ccaccggaca
    25921 gttttttcat gatcttggtc tgtgctgcac caccaacacg ggatacggaa atacccgggt
    25981 taaccgcagg acgaataccg gcgttgaaca ggttggtttc caggaagatc tgaccatcgg
    26041 taatggagat tacgttggtc ggaacgaacg cagaaacgtc acccgcctga gtttcgataa
    26101 tcggcagtgc ggtcagagaa ccggttttcc ctttcacttc acctttggtg aaggcttcaa
    26161 cgtattcggc gttaacacgt gcagcacgct ccagcagacg agagtggagg tagaaaacgt
    26221 cgcccgggaa tgcttcacgt cctggcggac gacggagcag cagggagatc tgacggtaag
    26281 caacagcctg tttagacagg tcatcgtaaa tgatcagcgc atcttcaccg cggtcacgga
    26341 agtattcgcc cattgcgcaa ccggcatacg gtgccaggta ttgcagtgca gcggattcag
    26401 acgcggttgc taccacaacg atggtgttag ccagtgcgcc gtgctcttcc agtttacgta
    26461 ccacgttaga aatggtggac gctttctggc cgatagcgac atagatacat ttgataccgg
    26521 aatcgcgctg gttgatgatg gcatcgatag ccagtgcggt tttacctgtc tgacggtcac
    26581 cgatgatcaa ttcacgctga ccacgaccga ttgggatcat ggagtcaacg gctttataac
    26641 cggtctgtac cggctgatct acggactgac gttcgataac gcccggagcg attgcttcta
    26701 cagcagagaa gccgtcgtga tccagcggac ctttaccgtc gattggtgca cccagagtgt
    26761 taaccacacg gcccagcagg ccacggccaa ccggaacttc caggatacgg ccagtacact
    26821 taactttcat gccttcggca aggtcagcgt acggacccat aacaaccgca cctacagagt
    26881 cgcgctcgag gttcagtgcg atagcgtaac ggttacccgg cagggagatc atttcaccct
    26941 gcatacaatc ggccaggccg tgaatgcgga taacaccgtc acttacagaa acaatagtac
    27001 cttcgttgtg agcttcactc acaacattga actgagcaat gcgctgcttg atcagttcgc
    27061 tgatttcggt ggaattcagt tgcatgctcc agtcccctta agactgcaag acgtctgcaa
    27121 ggcgctcaag acgaccgcgt acgctgccat caatgaccat atcacccgct cggatgataa
    27181 cgcctgccat tacagactta tcgattttgc aattcagctt aactttgcgt gacagacgtt
    27241 tttccatcgc agcagaaatt ttcgcgagct gttgttcact cagtgcggca gcggaaatga
    27301 cgtctacctc agcggtagcc tcactcacgg cacgcaggtg aataaactgc tccagaacat
    27361 ccgggagcgc gttaagacga ccattttcag ccataacccg aatcaggttc tgaccgtttt
    27421 cgtccagttg ctcaccacaa actgcgataa acgactcggc gagcgtttct ggcgcaagcg
    27481 cgccagagag aagctctgcc atttgttcgt ttttggttac ctcggcggca aacgccagca
    27541 tgtcctgcca gcgttctaca ctttggtgtt cgacggcaaa gtcaaaagct gctttggcgt
    27601 aggggcgagc taccgtaata aattcagaca tcagcccctc cctccttaca gttcagcgac
    27661 aagtttatcc acgatgtcgc tgttagcagc ttcatccacg gaacgttcga tgatcttctc
    27721 ggcgccagca acagccagga tagcaacttg cttacgcagc tcttcacggg cacgtttacg
    27781 ctcggcttca atttccgcct gcgcctgggc cacgatttta gtacgttcct gttctgcctc
    27841 agctttcgct tcgtccagaa tctgcgagcg gcgtttgttc gcctgctcga tgattacctg
    27901 ggcttccgct ttcgcttttt tcagctggtc ggtcgcgctg gcctttgcaa ggtcaaggtc
    27961 cttatgtgct cgttctgcgg aagcaaggcc gtcagcaatt tctttttgac gtttttcgat
    28021 ggctgccatt aatggcggcc atacgtactt catgcagaac agaacgaaca ggacaaacgc
    28081 gatggcctgg ccgaggattg ttgcgttaag attcacagca caatgcctct atttagttaa
    28141 cgttctgata ttgctcttta aataaaagca acgcttacta cgcgacagcg aacatcacgt
    28201 acagacccag acctacagcg atcatcggga tagcatccac cagacccata acgataaaga
    28261 actgagtacg cagcagagga atcagatcag gttgacgcgc tgcgccttcc aggaatttac
    28321 ccccgaggat gccgataccg atcgcagcac cgattgccgc cagacccatc atcacagcgg
    28381 cagccatgta cagcagatcc atattcaggt tttccatgac agtctccagt ttgtttcagt
    28441 taaaacgtag tagtgttggt aaattaatgt tcttcagacg ccatcgacag atagacgatc
    28501 gtcagaacca tgaagatgaa ggcttgcagc gtaatgatca ggatgtggaa aatggcccac
    28561 ggcacattca ggatccactg tgaccaccac ggcaacagac cagcaatcag aatgaaaatc
    28621 agctcaccgg catacatgtt accgaacagt cgcaaaccga gtgaaactgg tttggacagc
    28681 aggcttaccc cttcaaggat taagttgaca ggaatgaacg cccagtgatt gaacggctgc
    28741 agcgtcaact ctttcgtgaa gccgccgatg cctttcattt tgatgctgta gaacagaatc
    28801 aggataaata cgcccagtgc catagacagc gttacgttca cgtccgcaga cggaaccaca
    28861 cgcagtgcag gcagacccag tacatgttca gcaatgtacg gcagcaggtc gataggcagt
    28921 aaatccatca ggttcatcag gaatacccag acgaagatcg tcagggccag cggagcaatc
    28981 agcttgcttt tgccatggta catgtctttc acgctaccat taacaaagcc gatcaccagc
    29041 tcaatcgcgg tctgaaactt acctggcaca ccgctggtcg cctttttggc tacgctacgg
    29101 aataaaacca ggaacaacag acccagcacc accgagaaga acatggagtc aatattgatt
    29161 gtccagaagg tggctggggg gttttgtgga tccaccagcg agaatgtacg caggtccagc
    29221 tgaaggttat tcaggtggtg tcctatgtaa tcctgcggcg tcatattttc tgaagccatg
    29281 atgcctttta ccctttgttg ttaattacag ccggtgccag tatctgaacc accagcacca
    29341 aaacccacgt aacgatcagc ggcaagaata ccgcctttaa aaccgccaac gccaccacca
    29401 gtaacaccaa catcgccaga actttgaaag cttcgccaaa tgcgaatgtc caggccaccc
    29461 ggcctttcgc tggtgtatgc gcctggtgac gccaggcaaa tatcataaac aaaacgttag
    29521 gcagaaagac tgccaggccc ccgcttattg cagagacgcc ccagaagggg tctttgaggc
    29581 tgaacagcaa tccacttgct atcaccacca gtaactgaac gagcagaagc ttccgagcaa
    29641 cgtttcgact cacgagcgac acagacatca cgtttttcac tcctgctccc ttcgaggtat
    29701 gccgcgtgtc gtataaaact ttctttaagg cttagagtca agcatcaaaa agcggtcaaa
    29761 ttatacggtg cgcccccgtg atttcaaaca ataagtagcc aaaaggtgaa taaatgttta
    29821 aatatttttc cagtgcatac aattgcgact tttctgctaa ccctgttcga tcatgaaaaa
    29881 ctgtaaataa cgcgtaaaca ctggtgataa agcgtgcttc agatcacata ttgcgcatgt
    29941 tcgcgcacag catatttatt tacttggcaa atgatgcctt tgcaagttta tgatatttca
    30001 gtctaaaaac agatactgtt ttaataaatg acatttacac aacaaaaacc acccattgac
    30061 atttttaata atgttttaac agccaatgat ggttcttagc gccgattttt agcagactga
    30121 tattttcact aatgacttat tttctgctta ccaaaaaaag ccacgttatc ttgttgatgc
    30181 aaaagagtga acgtggcgtt aaatgtaacc agttatatca gtagaaaacc tggttgttgt
    30241 taacagtcta accggtcaat tttttatgat ttttttgata aaaattaaat tttatttgct
    30301 ttaatcacca ccagatgacg ttcgccatcc agggctggaa cctgaagttt aaccactgat
    30361 tcgacctgat attcttcggg caacaaagcg atttcatctt ccggcatttg ccctttcagc
    30421 gcgtagaaac ggccttgctc accaggaaga tggtggcacc agctcaccat atcgttcaga
    30481 gaggcaaaag cgcggctaat tacgccatca aatggcggct ctgaaggaaa ctcttctacc
    30541 ctgctctgta ctggttcaat attctccagt ttaagctcat gttgcacctg acgaaggaaa
    30601 cgcacgcgtt taccaaggct atccaacaga gtgaaatggg cttcaggacg cacgatagag
    30661 agtggaatgc ctggcagtcc tggtccggtg ccgacatcga taaaccgttc accttgcaga
    30721 tacggtgcca ccacaatgct atcgagaata tggcgtacca gcatctcatt aggatcgcgg
    30781 accgaagtca ggttgtacgc tttgttccat ttatgcagca tattcacgta ggcaataagc
    30841 tggtttttct ggtgatcggt aagcgaaata cctgcgtctt tcagcagtaa ggagagtttg
    30901 ttgagcacgg tgattacctg ttcttgatgc gttgcctggt aagcgggtgc ttaccaggca
    30961 tttttaatgc gttatgcgct acgacgcagc ataccctgtt ttttcagcca caccagcaga
    31021 atggagatgg ccgcaggcgt gacgccagaa atacgcgaag cttggccgat agaggctggt
    31081 ttgtgatcgt taagtttggc gatcacttcg ttagaaagac cggatacctg gcggtaatcc
    31141 agtgtcgcgg gtagcagggt gttctcgtta cgcagctgct tttcgatctc atcttgctgg
    31201 cgcgcgatat aaccttcgta tttaacctga atctcaacct gttccgccgc ctgttcgtct
    31261 gtcaacgcag gggcaaacgg cgtcagcgtg gttaattttt cataagtcat ttccggacga
    31321 cgcagcagat cttcaccact ggcttcacgg gaaagcggcg cagtcaggtg agcattcact
    31381 tcggctgcag cttccgccga cggggttacc caggtcgatt tcagacgctg acgctcacgc
    31441 tcgatattct caagtttctc gttaaagcgc gcccaacgtt cgtcatccac caggcccagt
    31501 tcacgaccga tttcagtcaa acgcagatcc gcattatctt cgcgtagcat cagacgatat
    31561 tctgcgcgcg aagtaaacat acgatacggt tctttggttc ctaaagtgca caggtcatca
    31621 actagtacgc cgagatacgc ctgagaacgt gccggagccc aaccttcttt gtcagcagac
    31681 agacgggcag cgttaagacc ggccagcaaa ccttgcgcag cggcttcttc gtaaccggta
    31741 gtgccgttaa tctgaccagc aaagaacagc ccctggataa acttgctctc cagcgtcggt
    31801 ttcaggtcgc gaggatcgaa gaagtcatac tcaatggcat aacccggacg cacgatcttc
    31861 gcgttttcca tcccctgcat agagcggacg atttgcatct gcacatcgaa cggcaggctg
    31921 gtggagatac cgttcggata aatttcatta gaggtcagtc cttccggttc aaggaagatc
    31981 tgatgctgat ttctgtcggc gaagcgcatg actttgtctt cgatcgacgg gcagtagcgt
    32041 gggccgacac cttcgatcac ccctgcgtac attgggctac gatcgaggtt actgcggatc
    32101 acatcatggg ttttctcgtt ggtatgagtg atataacacg gcacctgctg gggatgctgg
    32161 gacgcattgc ccataaacga gaataccggc attgggttat cgccatgctg ttgcgccagt
    32221 acgctaaagt cgatggttcg agcatcaata cgcggtggtg tcccggtttt cagacgacca
    32281 acgcgcagcg gcagttcacg caaacggcga gaaagcggaa tggacggcgg atcaccagca
    32341 cggccaccgc tgtaattatc cagaccgata tgaattttac cgtcgaggaa cgtcccaacg
    32401 gtgagcacga cggctttggc acggaacttc agtcccattt gggtaacagc accgaccacg
    32461 cgatcgtttt cgacaataag atcttcaacc gcctgctgga agatcatcag gttcggttgg
    32521 ttctccagcg ccgtacgtac cgcctgacgg tagagcacac gatccgcctg agctcgggta
    32581 gcgcgaaccg ccggtccttt gcttgcgttt agtatcctaa actggatacc cgcctgatcg
    32641 atcgctttcg ccatcagacc gccgagtgca tccacttctt ttaccagatg tcccttccca
    32701 ataccgccga tcgccgggtt gcagctcatc tgccccagag tgtcgatatt gtgtgtcaaa
    32761 agcagagtct gttgacccat acgcgccgcg gccatcgcgg cctcggtgcc tgcatgaccc
    32821 ccgccaatga taatgacgtc aaaaggatcc ggataaaaca tggtgattgc ctcgcataac
    32881 gcggtatgaa aatggattga agcccgggcc gtggattcta ctcaactttg tcggcttgag
    32941 aaagacccgg gatcctgggt attaaaaaga agatctattt atttagagat ctgttctatt
    33001 gtgatctctt attaggatcg cactgccctg tggataacaa ggatccggct tttaagatca
    33061 acaacctgga aaggatcatt aactgtgaat gatcggtgat cctggaccgt ataagctggg
    33121 atcagaatga ggggttatac acaactcaaa aactgaacaa ccgttgttct ttggataact
    33181 accggttgat ccaagcttcc tgacagagtt atccacagtg gatcgcacga tctgtatact
    33241 tatttgagta aattaaccca cgatcccagc cattcttctg ccggatcttc cggaatgtcg
    33301 tgatcaagaa tgttgatctt cagtgtttcg cctgtctgtt ttgcaccgga atttttgagt
    33361 tctgcctcga gtttatcgat agccccacaa aaggtgtcat attcacgact gccaataccg
    33421 attgcgccaa agcggactgc agaaagatcg ggcttctgtt cctgcaatgc ttcatagaaa
    33481 ggagaaaggt tgtccggaat atctccggca ccgtgggtgg agctgataac cagccagatc
    33541 cctgaggcag gtaaatcttc taacagcgga ccgtgcagcg tttcggtggt aaaacccgcc
    33601 tcttccagct tttcagccag gtgttctgct acatattcgg caccgccgag ggtgctgccg
    33661 ctgataagag tgatatctgc cataaaccgc cacctttatt aagagtggcg tattgtacgc
    33721 tgtgaacgcg ttgggatcta cctgtggaaa agtatgggat taaaaaagcc gatcagggct
    33781 tgatggtacg catgatcggg ttttgcagga cgatcaatgt ctcggtggac tgaatttcat
    33841 caattgtttg gatcttgttg ataagtacat gctggagagc gtcgatcgaa cggcacatca
    33901 cttttataaa gatgctgtag tggccggttg tgtaataggc ttcagtgact tcatcaaggc
    33961 tttccagctt tgccagcgcg gaagggtagt ctttggcgct ctttaatata atgccgataa
    34021 agcagcctac gtcataaccg agctgcttcg ggctgacatc aatacgcgcc ccggtaatga
    34081 tccccgcctg cttcattttc tctactcgaa cgtgaatcgt ccccggactg acgccaaatt
    34141 gtttcgccag ttcggcgtaa gcggtgcgcg cattgcccat taatgcttcc aggatgccac
    34201 ggtccagatt gtcgatcaga taattttcca taggattttc ttatgcggat tgatgattca
    34261 ttctatttta gccttctttt ttaatgaatc aaaagtgagt taggcttttt attgaatgat
    34321 tattgcatgt gtgtcggttt ttgttgctta atcataagca acaggacgca ggagtataaa
    34381 aaatgaaaac cgcttacatt gccaaacaac gtcaaattag cttcgtgaaa tctcactttt
    34441 ctcgtcaact ggaagaacgt ctggggctga tcgaagtcca ggcgccgatt cttagccgtg
    34501 tgggggatgg cacgcaggat aacttgtcgg gctgtgaaaa agcggtgcag gtaaaagtga
    34561 aagctctgcc tgatgcccag ttcgaagtgg ttcattcact ggcgaagtgg aaacgtcaga
    34621 ccttagggca acacgacttc agcgcgggcg aagggctgta cacgcacatg aaagcccttc
    34681 gccccgatga agaccgtctt tctccgttgc actcggtcta tgttgaccag tgggactggg
    34741 aacgcgtaat gggcgacggt gagcgtcaat tctcgactct gaaaagcacg gtagaggcga
    34801 tctgggcggg aattaaagca accgaagctg cggttagcga agagtttggc ctggcaccgt
    34861 tcctgccgga tcagatccac ttcgtacaca gccaggagtt actgtctcgt tatccggatc
    34921 ttgatgccaa agggcgtgag cgggcgatag cgaaagatct tggcgcggta ttccttgtcg
    34981 ggattggcgg caagctgagc gatggtcatc gccacgacgt gcgcgcaccg gattatgatg
    35041 actggagcac cccgtcagag ctgggccatg cgggtctgaa cggcgatatt ctggtgtgga
    35101 acccggtact ggaagatgcg tttgagcttt cctccatggg gatccgtgta gatgccgaca
    35161 cgctgaagca tcaactggcg ctgaccggtg acgaagatcg cctggagctg gagtggcatc
    35221 aggcgctgct gcgcggtgaa atgccgcaga ccatcggcgg cggtatcggc cagtctcgtt
    35281 tgactatgct gctgctgcaa ctgccgcata tcggccaggt tcagtgtgga gtatggccag
    35341 ctgctgttcg cgagagcgtc ccttctctgc tgtaataatt tatcgccgcc agcgtctgag
    35401 caggcggctt cgcatcccgg tatcaaagcg ccagatatga tcgaaaatgc gcatgatgcc
    35461 gggtttgccg tgtgccgaca tcgccacggc atgaaagcga tgctgatgta cccgctgcag
    35521 ctctttcact ttactcgtca cgtcgtcagg caaccgctga gcgataaaat cagaaatcac
    35581 caccgcatcg gcatcaaacc attccctgct ttgcaagcgt tccataatgg cgcgaaaaca
    35641 actggcaaga tcggtgccgc cacgaaactg ctggcttaaa aaacggattg cttgttcgat
    35701 gccttgtggg cctgaaagct cataacggac gatctcggtg gaaaatagca taatatagca
    35761 gcgccggttt tctgcgagag caatgcgcat caaggccagg cagaacgctt tcgcacactg
    35821 ttcattaaag ccgcccattg agccggaagt atccacacag acaataaacg gcccgcgcgg
    35881 ctgttcatcg taatctttat gtaccaccgg acgttcgatc actttttcac gccacgactc
    35941 accgtgcagg cgataggtga gcaactgttt ttccaccagc cgacggtaaa actcatactc
    36001 cagttccgtt atccctagtg tcgccagttc tggcggcagg agacgtaaaa tatcatcgct
    36061 ttgttgcaga ccatcaacct gctcaggaac cgtcgccggt tcgcgcacca tggtgcggaa
    36121 ggtttccatc tgcgcatcgt tgcgcggtat tgatttggct tcccgagaac gccccagctg
    36181 ctctgccagg cgtttcagtt ccggctgttc gttaagaaat tcaccgtatt tcacaatcaa
    36241 ctgatagtcg ccacgtttaa gctgaccggc gctcatatcc cacagacgac cagctgcagt
    36301 attgttatct gcgagaatcg gttcaagttg tccgctcagc gtcatgcgtt cctgaacttc
    36361 actcaacagt tgttcgcgtt cttcttctaa tagctgttga tttaacgtcg ttgcttgcac
    36421 gatcagactt aaacgccaac gctggagaaa aagcgtgtgt aacgctgaag tgatcgtgct
    36481 gttagcatca accaactgtc gggcttgttc tgcccatgga gaattcagac gatgcagtaa
    36541 gtccaggatc tgtggtagct gcacaataaa ctgtggcgtg gagaggagct ggctttgctg
    36601 atagcacatc acctcttcgg tgagttccgg cgggactcgg gcatctttca gccgactgcg
    36661 cagcgcttca cgccagcggg gaacatcatc agtgattgcc gccttcaggc gtgggaattt
    36721 ttcaaagaag accgccagct gcggtgaggc cagcagtgcg atgatcatct cttcgatcaa
    36781 tccctcttcg ctgacggcca gcatcacatt aagcgtatcc agcgttagca ttgttgtgcc
    36841 tggcgaatct gtgcaccgac atcctgtagg ctggcttcaa tgcgacctaa ccagtcgcca
    36901 gggataaaca gacatttttg ctgttcgctg aataaagcgt gttgcttgcg ccagtcgctt
    36961 tcaagctctt ccagttgttg ttttatttca ccaggcagac cttcagccga tgaaccggga
    37021 agtgccagcg tactgccttg taaacttaca tcgcgaacga caagatgttg ggcgctatca
    37081 acttccagat tcagtttctg ggcaaagccg ataccgttca gtttaccgcg aatttcacca
    37141 cctttgctca gccactgttc cagcgcgcta cgctcaaagg agatatgaac cacttccata
    37201 tcatgcagtt ttaacggttt ttgcagcagt agagtcagag tggaagcagt aacgttaaca
    37261 ggaagttgat actgctgacg acggctgaaa atgccgccca gacgaattac cgttaaggct
    37321 gttttatcgc tttgttgctg ctggagttgc aggtgacgtt gcacaatcgc gccaaggcga
    37381 gtcaacatcc cttgctgttg ccaggcgtga ccggtcatca atacatcaat ttgttgttgt
    37441 atcaaattca ggctttgcgc gtcataccac aggcaatctt tcagcaaaat gagatctacc
    37501 ggggcaacag cactgcgacc gctaaaaaag gcgctggcct gcaataatcg gatcgctttt
    37561 ttccagcgac gatccgagac ataaggcgca tccggtaatt tatccagttg ctggcgcagc
    37621 ataaaaatca gctcaaatac atgatcgggc agcgtaattt caccaatctc tttctgccag
    37681 cgttcatatt cttcatctgt gacctgcaag gcatcaggaa ccggattgtc gttttcatcc
    37741 tgttgactgg tcagcatgga gcggaaattc gctttatcct gcactttatc taaccacaga
    37801 cgaatcagca tgcggtcata taacgcttcc agactgctgt ctgcttccgg cagctcgttg
    37861 gaggccgcca ccagcagacg catcgggatt ttttctacgt gtgcaccgtt gcggaactgg
    37921 cgctcgttaa tggcggtgag caaggtatta agaattgccg ggcccgcttt ccagatctca
    37981 tccagaaaga caatttctgc ttccggcagg taaccgctgg ttaaacgttc atagcgccct
    38041 tcatctttta gcgcctgaat agaaagggga ccaaaaactt cttccggcgt ggagaagcgg
    38101 gtcatcagat attcaaacgc gcgggcattc tgaaaggcga attttaagcg ccgggcgatc
    38161 aaacttttgg caatacctgg cgggccaagg aggaacacac tttcaccact taatgccgct
    38221 aataaacaca agcggatggc gtggctacgt tcataaagcc ccttttccaa cgaactgctc
    38281 aggcgggaaa ttctttccgc taataaatga gggtgagcca taatgaagtg gcgtcctttc
    38341 gtcaaaagtt ctgcgtaaat tgcgagtata gacgtttctt gctggtggct aaaatagtct
    38401 caaagggggg gtatttttct ttgagccagg ttaatgtggc cgcatttagg agtacgattt
    38461 tgccgttaat cgtgcatact gtgcgctttt ttgtgggcca agggactaag cacacatttc
    38521 atatttcaac gaaagactag tctatgagca ctgataataa gcaatcattg cccgcgatta
    38581 ccctcgcggc gattggagtt gtctacggcg atattggtac cagcccgtta tatacacttc
    38641 gtgaatgttt gtccggccag tttggttttg gcgttgaacg cgatgccgtg tttggctttt
    38701 tatcgctgat cttctggctg ctaatctttg tggtttccat taaatatctc accttcgtga
    38761 tgcgggcaga taacgccggt gaggggggga tcctgacgtt gatgtcgctt gccgggcgta
    38821 atacgtcggc gcgaaccaca tcaatgctgg tgattatggg gctaatcggc ggcagctttt
    38881 tctatggtga agtcgtcata acacccgcta tttcggtgat gtcagccatt gaaggtctgg
    38941 aaatcgtcgc cccgcagctg gatacctgga tagttcccct ctcaattatc gttctcactt
    39001 tattatttat gattcaaaaa catggcacgg ctatggtcgg taagctgttt gcgccgatca
    39061 tgctgacctg gtttttgatt ctggcaggac tggggttacg tagcattatt gctaacccgg
    39121 aagtgctgca tgcgctgaat ccaatgtggg cggtgcattt cttccttgaa tacaaaacgg
    39181 tttcttttat tgcattaggg gcagtggtgt tgtcgattac gggggtcgag gcgctgtatg
    39241 ctgatatggg gcactttggt aagttcccta ttcgcctggc gtggttcacc gtcgtattac
    39301 cttccttgac ccttaattac ttcggtcagg gagcgctgtt gttaaagaac ccggaagcga
    39361 ttaagaaccc gttcttcctg ttggcaccgg actgggcgct gatcccgctg ctgatcatcg
    39421 ccgcactggc gacggtaatt gcctcgcagg cggttatctc tggcgtcttc tcattgacgc
    39481 gtcaggcggt acgtctggga tatttgtcgc cgatgcgcat tattcacacc tccgaaatgg
    39541 agtcagggca aatctatatt ccgtttgtga actggatgct ctatgtcgcg gtcgtgattg
    39601 tgattgtcag ctttgagcac tccagcaacc tggcggcggc gtacgggatt gcggtgaccg
    39661 gaaccatggt gctgacgtct attctctcga ctaccgtggc acgtcagaac tggcactgga
    39721 ataagtattt tgttgcgctg atcctgattg ctttcctttg tgtcgatatt ccattgttca
    39781 ccgctaacct cgataaactg ctctccggcg gctggttgcc attgagcctc ggtactgtga
    39841 tgtttatcgt gatgaccacc tggaagagcg agcgtttccg cttgctgcgg cggatgcatg
    39901 aacatggtaa ctctctggaa gcgatgattg cttcgctgga gaaatcaccg cctgttcgcg
    39961 tgcccgggac cgcggtgtat atgtcgcgtg caatcaacgt cattcccttt gcgctgatgc
    40021 ataaccttaa acataacaag gtattgcatg agcgggtgat tctgttaact ctgcgtaccg
    40081 aagacgcgcc atatgtccat aatgtccgtc gggtacagat tgaacaactg tcgcccactt
    40141 tctggcgcgt ggtggcaagt tatggttggc gagaaacgcc aaacgtggaa gaagttttcc
    40201 accgctgcgg tctggaagga ttaagttgcc ggatgatgga aacctccttc tttatgtcgc
    40261 atgagtcgtt gatcctcggc aaacgcccgt ggtatttgcg tctgcgcggc aagctgtact
    40321 tgctgctgca acgtaatgcg ctgcgtgcac cagatcaatt tgaaattccg ccaaacaggg
    40381 ttatcgaact gggtactcag gtcgaaatct aacgccagac gcctcctttc tccataaggg
    40441 ggcgtttttg ttttcatggt taatcaccat gtaaaacgtt tcgaggttga tcacatttcc
    40501 gtaacgtcac gatggttttc ccaactcagt caggattaaa ctgcgggtca gcgaaacgtt
    40561 tcgctgatgg agaaaaaaat gaaaaaaggc accgttctta attctgatat ttcatcggtg
    40621 atctcccgtc tgggacatac cgatacgctg gtggtgtgtg atgctggttt acccatcccc
    40681 aaaagtacaa cgcgtatcga tatggcatta acccagggtg taccttcttt tatgcaggtg
    40741 ctgggcgtcg tcacaaatga aatgcaggtc gaggctgcca ttatcgcgga agagatcaaa
    40801 caacataatc cgcaactcca cgaaacgttg ctcactcacc ttgagcagct gcaaaaacac
    40861 cagggaaata ccattgaaat tcgttacacc acgcatgaac aattcaaaca acaaaccgca
    40921 gaaagtcagg cggtaattcg cagcggagaa tgttctccgt atgcgaatat cattctctgt
    40981 gctggcgtga cgttctgagg ccgtcatgga agcattactt cagcttaaag gcatcgataa
    41041 agccttcccg ggcgtaaaag ccctctcggg cgcagcgtta aatgtctatc cgggccgcgt
    41101 gatggcgctg gtgggcgaaa acggcgcggg taaatccacc atgatgaaag tgcttactgg
    41161 tatctatgct cgcgatgccg gcacgctttt atggctgggg aaagaaacga catttaccgg
    41221 gccgaaatct tcccaggaag ccgggattgg gattatccat caggaactga acctgatccc
    41281 gcagttgacc attgccgaaa acattttcct cggtcgtgag tttgttaatc gctttggcaa
    41341 aattgactgg aaaaccatgt atgccgaagc ggataaattg ctggctaaac ttaacctgcg
    41401 ctttaaaagc gacaagctgg tgggcgatct ttccatcggt gaccagcaaa tggttgaaat
    41461 cgccaaagtg ctgagctttg agtcgaaagt catcattatg gatgaaccga ccgatgcgct
    41521 gaccgatacc gaaaccgaat ccctgttccg cgtcatccgc gagctgaaat cgcaaggccg
    41581 cggtattgtc tatatctccc accgcatgaa agaaatcttc gagatttgcg atgacgttac
    41641 cgtttttcgt gatgggcaat ttattgctga gcgcgaagtg gcatcactga ccgaagattc
    41701 gctgattgag atgatggtgg gtcgcaagct ggaagatcaa tatccgcacc tggacaaagc
    41761 gccgggagat atccgcctga aagtcgataa tctctgcgga cctggcgtta acgatgtctc
    41821 ttttacttta cgcaaaggcg aaattcttgg cgtctctggt ttgatgggcg caggtcgtac
    41881 cgaactgatg aaagtgctct acggcgcact accgcgcacc agcggttacg tcaccctgga
    41941 tgggcatgaa gtcgttaacc gttcaccgca ggatggcttg gcaaacggca ttgtgtatat
    42001 ctccgaagac cgtaaacgtg acggtttagt gttgggcatg tcagtaaaag agaacatgtc
    42061 gctgacagcg ctgcgctact tcagccgcgc tggcggcagt ttgaagcatg ccgatgaaca
    42121 gcaggctgtg agtgatttca ttcgtctgtt taatgtgaaa actccgtcga tggaacaggc
    42181 aattggtctg ctttccggtg gcaatcagca aaaagtggcg attgcccgcg gtctgatgac
    42241 acgccccaaa gtgttgatcc ttgatgaacc tacccgtggc gtagatgtcg gcgcgaaaaa
    42301 agagatctat caactgatta accagttcaa agccgatggc ttgagcatca ttctggtgtc
    42361 atcggagatg ccagaagtat taggcatgag cgatcgcatc atcgtcatgc atgaagggca
    42421 tctcagcggg gaatttactc gtgagcaggc cacccaggaa gtgttaatgg ctgccgctgt
    42481 gggcaagctt aatcgcgtga atcaggagta aaaaaatgac aacccagact gtctctggtc
    42541 gccgttattt cacgaaagcg tggctgatgg agcagaaatc gcttatcgct ctgctggtgc
    42601 tgatcgcgat tgtctcgacg ttaagcccga actttttcac catcaataac ttattcaata
    42661 ttctccagca aacctcagtg aacgccatta tggcggtcgg gatgacgctg gtgatcctga
    42721 cgtcgggcat cgacttatcg gtaggttctc tgttggcgct gaccggcgca gttgctgcat
    42781 ctatcgtcgg cattgaagtc aatgcgctgg tggctgtcgc tgctgctctc gcgttaggtg
    42841 ccgcaattgg tgcggtaacc ggggtgattg tagcgaaagg tcgcgtccag gcgtttatcg
    42901 ctacgctggt tatgatgctt ttactgcgcg gcgtgaccat ggtttatacc aacggtagcc
    42961 cagtgaatac cggctttact gagaacgccg atctgtttgg ctggtttggt attggtcgtc
    43021 cgctgggcgt accgacgcca gtctggatca tggggattgt cttcctcgcg gcctggtaca
    43081 tgctgcatca cacgcgtctg gggcgttaca tctacgcgct gggcggcaac gaagcggcaa
    43141 cgcgtctttc tggtatcaac gtcaataaaa tcaaaatcat cgtctattct ctttgtggtc
    43201 tgctggcatc gctggccggg atcattgaag tggcgcgtct ctcctccgca caacccacgg
    43261 cggggactgg ctatgagctg gatgctattg ctgcggtggt tctgggcggt acgagtctgg
    43321 cgggcggaaa aggtcgcatt gttgggacgt tgatcggcgc attaattctt ggcttcctta
    43381 ataatggatt gaatttgtta ggtgtttcct cctattacca gatgatcgtc aaagcggtgg
    43441 tgattttgct ggcggtgctg gtagacaaca aaaagcagta ataacgacta caggacatct
    43501 tgaatatgaa catgaaaaaa ctggctaccc tggtttccgc tgttgcgcta agcgccaccg
    43561 tcagtgcgaa tgcgatggca aaagacacca tcgcgctggt ggtctccacg cttaacaacc
    43621 cgttctttgt atcgctgaaa gatggcgcgc agaaagaggc ggataaactt ggctataacc
    43681 tggtggtgct ggactcccag aacaacccgg cgaaagagct ggcgaacgtg caggacttaa
    43741 ccgttcgcgg cacaaaaatt ctgctgatta acccgaccga ctccgacgca gtgggtaatg
    43801 ctgtgaagat ggctaaccag gcgaacatcc cggttatcac tcttgaccgc caggcaacga
    43861 aaggtgaagt ggtgagccac attgcttctg ataacgtact gggcggcaaa atcgctggtg
    43921 attacatcgc gaagaaagcg ggtgaaggtg ccaaagttat cgagctgcaa ggcattgctg
    43981 gtacatccgc agcccgtgaa cgtggcgaag gcttccagca ggccgttgct gctcacaagt
    44041 ttaatgttct tgccagccag ccagcagatt ttgatcgcac taaaggtttg aacgtaatgc
    44101 agaacctgtt gaccgctcat ccggatgttc aggctgtatt cgcgcagaat gatgaaatgg
    44161 cgctgggcgc gctgcgcgca ctgcaaactg ccggtaaatc ggatgtgatg gtcgtcggat
    44221 ttgacggtac accggatggc gaaaaagcgg tgaatgatgg caaactagca gcgactatcg
    44281 ctcagctacc cgatcagatt ggcgcgaaag gcgtcgaaac cgcagataaa gtgctgaaag
    44341 gcgagaaagt tcaggctaag tatccggttg atctgaaact ggttgttaag cagtagtttt
    44401 aatcaggttg tatgacctga tggtgacata aatacgtcat cgacagatga acgtgtaata
    44461 taaagaaaag cagggcacgc gccaccctaa cacggtggcg cattttatgg acatcccgaa
    44521 tatgcaaaac gcaggcagcc tcgttgttct tggcagcatt aatgctgacc acattcttaa
    44581 tcttcaatct tttcctactc caggcgaaac cgtaaccggt aaccactatc aggttgcatt
    44641 tggcggcaaa ggcgcgaatc aggctgtggc tgctgggcgt agcggtgcga atatcgcgtt
    44701 tattgcctgt acgggtgatg acagcattgg tgagagcgtt cgccagcagc tcgccactga
    44761 taacattgat attactccgg tcagcgtgat caaaggcgaa tcaacaggtg tggcgctgat
    44821 ttttgttaat ggcgaaggtg agaatgtcat cggtattcat gccggcgcta atgctgccct
    44881 ttccccggcg ctggtggaag cgcaacgtga gcgtattgcc aacgcgtcag cattattaat
    44941 gcagctggaa tcaccactcg aaagtgtgat ggcagcggcg aaaatcgccc atcaaaataa
    45001 gactatcgtt gcgcttaacc cggctccggc tcgcgaactt cctgacgaac tgctggcgct
    45061 ggtggacatt attacgccaa acgaaacgga agcagaaaag ctcaccggta ttcgtgttga
    45121 aaatgatgaa gatgcagcga aggcggcgca ggtactgcat gaaaaaggta tccgtactgt
    45181 actgattact ttaggaagtc gtggtgtatg ggctagcgtg aatggtgaag gtcagcgcgt
    45241 tcctggattc cgggtgcagg ctgtcgatac cattgctgcc ggagatacct ttaacggtgc
    45301 gttaatcacg gcattgctgg aagaaaaacc attgccagag gcgattcgtt ttgcccatgc
    45361 tgccgctgcg attgccgtaa cacgtaaagg cgcacaacct tccgtaccgt ggcgtgaaga
    45421 gatcgacgca tttttagaca ggcagaggtg acgcttggct acaatgaaag atgttgcccg
    45481 cctggcgggc gtttctacct caacagtttc tcacgttatc aataaagatc gcttcgtcag
    45541 tgaagcgatt accgccaaag ttgaagcggc gattaaagaa ctcaattacg cgccatcagc
    45601 tctggcgcgt agcctcaaac tcaatcaaac acataccatt ggcatgttga tcactgccag
    45661 taccaatcct ttctattcag aactggtgcg tggcgttgaa cgcagctgct tcgaacgcgg
    45721 ttatagtctc gtcctttgca ataccgaagg cgatgaacag cggatgaatc gcaatctgga
    45781 aacgctgatg caaaaacgcg ttgatggctt gctgttactg tgcaccgaaa cgcatcaacc
    45841 ttcgcgtgaa atcatgcaac gttatccgac agtgcctact gtgatgatgg actgggctcc
    45901 gttcgatggc gacagcgatc ttattcagga taactcgttg ctgggcggag acttagcaac
    45961 gcaatatctg atcgataaag gtcatacccg tatcgcctgt attaccggcc cgctggataa
    46021 aactccggcg cgcctgcggt tggaaggtta tcgggcggcg atgaaacgtg cgggtctcaa
    46081 cattcctgat ggctatgaag tcactggtga ttttgaattt aacggcgggt ttgacgctat
    46141 gcgccaactg ctatcacatc cgctgcgtcc tcaggccgtc tttaccggaa atgacgctat
    46201 ggctgttggc gtttaccagg cgttatatca ggcagagtta caggttccgc aggatatcgc
    46261 ggtgattggc tatgacgata tcgaactggc aagctttatg acgccaccat taaccactat
    46321 ccaccaaccg aaagatgaac tgggggagct ggcgattgat gtactcatcc atcggataac
    46381 ccagccgacc cttcagcaac aacgattaca acttactccg attctgatgg aacgcggttc
    46441 ggcttagatt tacgctgtct tttgatcaaa ttattaccat cggttgtttt cagaagcatg
    46501 aacattgctg ctgaagcaac agtaataatg cccattgtga taaacgtata gtggaattgt
    46561 tcgacagtcg ttgtgccttc cattccttca taaacgcgaa ggacggccgc acttacagca
    46621 acgcctaaac taatcgacag ttgctgcgtg accgccagaa cactgttacc gctgctggca
    46681 ttgtcatcgg tcagatcggc aagtgtgatg gtattcatcg cggtaaactg cgtcgacata
    46741 gccatcccta atataaacaa cggcaagatc agcatccata tagccattgc tggtgattgc
    46801 aaagagaact gagcgatcat tagcccaata atcaccgtga tccccactaa cgtatggcga
    46861 tagcccagac gacgtaagac ttgggtaacc atcgattttg caataatgga acctaacgct
    46921 gtcggtgcca tcatacagcc agcaataaac gcctgataac caaatcctac ctgtaacatc
    46981 aatggcataa ggaacggtac acagccggtc cccagacggg ttgcaatatt gcctacgata
    47041 ccgatcgaga aagtgcgggt tttaaataaa tctaatgaaa ttaatgggtt tggcgtgcgt
    47101 cgtgcatgga gaatatagag aagcagtaac ccgatgctgg tgacaattac cgtcaaggca
    47161 atccagctgg cgacaatctt ttccccgaat agctctattc cgcttgagaa gagaacaagg
    47221 ctgaggccaa acagcaaaaa gccagtgata tcgaatctgc gtcgtgcggt ggtgaaattg
    47281 ggcatatgtt tgcgcgcgta aagaaggccc gcaataccta tggggatatt gattaaaaat
    47341 atccagtgcc aggttgccca ggtgaccagc acgccgccaa gaacggggcc taaaattggc
    47401 cccaccagac ccggcatggc gacaaaattc aatactggaa gaagttcatt acgaggataa
    47461 gcgcgcagta aggccagccg agcaacaggc atcatcattg cgccgcctat cccctgaata
    47521 acccggaaga caaccagctg tggtagcgaa ttagaaagtg cgcaggccag agaacccaat
    47581 gtgaacagac tcacggcaag ggtaaaaatg cgacgcgtac cgaagcgatc ggctagccat
    47641 ccgcttaccg gaataagcat cgccaccgtc agcgtataac tgatgatggc tgattgcatc
    47701 gcgagaggag aacgattaag gctatgagcg attgcgggta aggcggtatt aagaatagtg
    47761 gcatcaagtg cctgcatgaa gaaggccatc gccgcgatcc acggcaaacc cgccatactg
    47821 cgcttctttt tatcgctcat tcaatgtcct gttatcgggt tatcacttat caggtgagcg
    47881 tagcagcgcc tgacaagctt taaatgccgc gtcgccatcg ctttggataa tcgcatcgac
    47941 aatcgcctga tgcagatcca gctttatcac tgtgtcgctg gtaattgacg tgaagtaagt
    48001 gtgataaacc gaatggaata gcgaggcgaa tgaggtcaaa aacggattgg cgctcatttc
    48061 atagatatgc tcatgccagg ccatatcgac ttcgatccag cgttcacggc gaaagttctc
    48121 ttttaatgcc gccatttcgg ccattaacgt attgagatgc gctttctgtt ccgcggtgcc
    48181 aaccgttgct gccagtaggc aggcttgcgg ctccagacag atacgcataa ccagaaagtg
    48241 atcgatgacc tgatgaaagt tctcttctgt catccaccag gtaagcaatt cctgatcaag
    48301 aaaattccag ttcgattgtg gcatgacccg agtaccaatt cgcggtcgcg gtaaaaccat
    48361 cccttttgcc gttaacgttt tgaccgcttc gcgtaccgct gtacgactca ctccaaattg
    48421 ctcgcccagc tcaatctcac cgggcaaaat ggtgccgggt tcatattcac cttttaagat
    48481 ccgttgcgcc agcttctcag ccagaacata cgaaaggttt ttctgtgcag ctaactgttg
    48541 tgcgcttaaa ggcattactt atcttccttt ttctttttat tcctccttag tatgccacca
    48601 ggaagtgtga ttacggttgc aaaaacggca aattgcttgt tttatggcac attaacgggg
    48661 cttttgctga aaaaatgcgc ggtcagaaaa ttattttaaa tttcctcttg tcaggccgga
    48721 ataactccct ataatgcgcc accactgaca cggaacaacg gcaaacacgc cgccgggtca
    48781 gcggggttct cctgagaact ccggca
//
LOCUS       DAPGUL010000021        48206 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.021, whole genome shotgun sequence.
ACCESSION   DAPGUL010000021 DAPGUL010000000
VERSION     DAPGUL010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 48206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 48206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..48206
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.021"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(258..521)
                     /gene="cedA"
                     /locus_tag="RHX21_001357"
     CDS             complement(258..521)
                     /gene="cedA"
                     /locus_tag="RHX21_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division activator CedA"
                     /protein_id="HDV1986572.1"
                     /translation="MRLVKPVMKKPLRQQNRQIISYVPRTEPAPPEHAIKMDSFRDVW
                     MLRSKYVAFVLMGESFLRSPAFTVPESAQRWANQIRQEGEVTE"
     gene            704..2965
                     /gene="katE"
                     /locus_tag="RHX21_001358"
     CDS             704..2965
                     /gene="katE"
                     /locus_tag="RHX21_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase HPII"
                     /protein_id="HDV1986573.1"
                     /translation="MSQHNEKNPHQHQSPLHDSSEAKPGMDSLAPEDGSHRPAAEPTP
                     PGAQPTAPGSLKAPDTRNEKLNSLEDVRKGSENYALTTNQGVRIADDQNSLRAGNRGP
                     TLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKSLSDITKADFLSDPNKIT
                     PVFVRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFV
                     HAVKPEPHWAIPQGQSAHDTFWDYVSLQPETLHNVMWAMSDRGIPRSYRTMEGFGIHT
                     FRLINAEGKATFVRFHWKPLAGKASLVWDEAQKLTGRDPDFHRRELWEAIEAGDFPEY
                     ELGFQLIPEEDEFKFDFDLLDPTKLIPEELVPVQRVGKMVLNRNPDNFFAENEQAAFH
                     PGHIVPGLDFTNDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHR
                     MGIDTNPANYEPNSINDNWPRETPPGPKRGGFESYQERVEGNKVRERSPSFGEYYSHP
                     HLFWLSQTPFEQRHIVDGFSFELSKVVRPYIRERVVDQLAHIDLTLAQAVAKNLGIEL
                     TDDQLNITPPPDVNGLKKDPSLSLYAIPDGDVKGRVVAILLNDEVRSADLLAILKALK
                     AKGVHAKLLYSRMGEVTADDGTVLPIAATFAGAPSLTVDAVIVPCGNIADIADNGDAN
                     YYLMEAYKHLKPIALAGDARKFKATIKVADQGEEGIVEADSADGSFMDELLTLMAAHR
                     VWSRIPKIDKIPA"
     gene            complement(3012..3770)
                     /gene="chbG"
                     /locus_tag="RHX21_001359"
     CDS             complement(3012..3770)
                     /gene="chbG"
                     /locus_tag="RHX21_001359"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HDV1986574.1"
                     /translation="MERLLIVNADDFGLSKGQNYGIIEACRNGIVTSTTALVNGQAID
                     HAVQLSRDEPSLAIGMHFVLTMGKPLTAMPGLTRDGVLGKWIWQLAEEDALPLEEITQ
                     ELASQYLRFIELFGRKPTHLDSHHHVHMFPQIFPIVVRFAAEEGIALRIDRQPLSNAG
                     DLPANLRSSQGFSSAFYGEEISEALFLQVLDDSSHRRERSLEVMCHPAFVDNLIRKSA
                     YCFPRLTELEVLTSASLKYAIAERGYRLGSYLDV"
     gene            complement(3783..5135)
                     /gene="celF"
                     /locus_tag="RHX21_001360"
                     /gene_synonym="chbF"
     CDS             complement(3783..5135)
                     /gene="celF"
                     /locus_tag="RHX21_001360"
                     /gene_synonym="chbF"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDV1986575.1"
                     /translation="MSQKLKVVTIGGGSSYTPELLEGFIKRYHELPVSELWLVDVEDG
                     KEKLDIIFELCQRMIDNAGVPMKLYKTLDRREALKDADFVTTQLRVGQLPARELDERI
                     PLSHGYLGQETNGAGGLFKGLRTIPVIFDIVKDVEELCPNAWVINFTNPAGMVTEAVY
                     RHTGFKRFIGVCNIPIGMKMFIRDVLMLKDSDDLSIDLFGLNHMVFIKDVLVNGKSRF
                     AELLDGVASGQLKASSVKNIFDLPFSEGLIRSLNLLPCSYLLYYFKQKEMLAIEMGEY
                     YKGGARAQVVQKVEKQLFELYKNPELKVKPKELEQRGGAYYSDAACEVINAIYNDKQA
                     EHYVNIPHHGHIDNIPADWAVEMTCKLGRDGATPHPRITHFDDKVMGLIHTIKGFEIA
                     ASNAALSGEFNDVLLALNLSPLVHSDRDAELLAREMILAHEKWLPNFADCIAELKKAH
                     "
     gene            complement(5240..6082)
                     /gene="chbR"
                     /locus_tag="RHX21_001361"
     CDS             complement(5240..6082)
                     /gene="chbR"
                     /locus_tag="RHX21_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ChbR"
                     /protein_id="HDV1986576.1"
                     /translation="MMQPVINAPEIATAREQQLFNGKNFHVFIYNKTESISGLHQHDY
                     YEFTLVLTGRYFQEINGKRVLLERGDFVFIPLGSHHQSFYEFGATRILNVGISKRFFE
                     QHYLPLLPYCFVASQVYRTNNAFLTYVETVISSLNFRETGLEEFVEMVTFYVINRLRH
                     YREEQVIDDVPQWLKSTVEKMHDKEQFSESALENMVTLSAKSQEYLTRATQRYYGKTP
                     MQIINEIRINFAKKQLEMTNYSVTDIAFEAGYSSPSLFIKTFKKLTSFTPKSYRKKLT
                     EFNQ"
     gene            complement(6090..6440)
                     /gene="chbA"
                     /locus_tag="RHX21_001362"
     CDS             complement(6090..6440)
                     /gene="chbA"
                     /locus_tag="RHX21_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIA"
                     /protein_id="HDV1986577.1"
                     /translation="MMDLDNIPDTQTEAEELEEVVMGLIINSGQARSLAYAALKQAKQ
                     GDFAAAKAMMDQSRMALNEAHLVQTKLIEGDAGEGKIKVSLVLVHAQDHLMTSMLARE
                     LITELIELHEKLKA"
     gene            complement(6491..7849)
                     /gene="chbC"
                     /locus_tag="RHX21_001363"
     CDS             complement(6491..7849)
                     /gene="chbC"
                     /locus_tag="RHX21_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIC"
                     /protein_id="HDV1986578.1"
                     /translation="MSNVIASLEKVLLPFAVKIGKQPHVNAIKNGFIRLMPLTLAGAM
                     FVLINNVFLSFGEGSFFYSLGIRLDASTIETLNGLKGIGGNVYNGTLGIMSLMAPFFI
                     GMALAEERKVDALAAGLLSVAAFMTVTPYSVGEAYAVGANWLGGANIISGIIIGLVVA
                     EMFTFIVRRNWVIKLPDSVPASVSRSFSALIPGFIILSVMGIIAWALNTWGTNFHQII
                     MDTISTPLASLGSVVGWAYVIFVPLLWFFGIHGALALTALDNGIMTPWALENIATYQQ
                     YGSVEAALAAGKTFHIWAKPMLDSFIFLGGSGATLGLILAIFIASRRADYRQVAKLAL
                     PSGIFQINEPILFGLPIIMNPVMFIPFVLVQPILAAITLAAYYMGIIPPVTNIAPWTM
                     PTGLGAFFNTNGSVAALLVALFNLGIATLIYLPFVVVANKAQNAIDKEESEEDIANAL
                     KF"
     gene            complement(7934..8254)
                     /gene="chbB"
                     /locus_tag="RHX21_001364"
     CDS             complement(7934..8254)
                     /gene="chbB"
                     /locus_tag="RHX21_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIB"
                     /protein_id="HDV1986579.1"
                     /translation="MEKKHIYLFCSAGMSTSLLVSKMRAQAEKYEVPVIIEAFPETLA
                     GEKGQNADVVLLGPQIAYMLPEIQRLLPNKPVEVIDSLLYGKVDGLGVLKAAVAAIKK
                     AAAN"
     gene            complement(8553..8891)
                     /gene="osmE"
                     /locus_tag="RHX21_001365"
     CDS             complement(8553..8891)
                     /gene="osmE"
                     /locus_tag="RHX21_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotically-inducible lipoprotein OsmE"
                     /protein_id="HDV1986580.1"
                     /translation="MNKNMAGILSAAAVLTMLAGCTAYDRTKDQFVQPVVKDVKKGMS
                     RAQVAQIAGKPSSEVSMIHARGTCQTYILGQRDGKAETYFVALDDTGHVINSGYQTCA
                     EYDTDPQAAK"
     gene            9093..9920
                     /gene="nadE"
                     /locus_tag="RHX21_001366"
     CDS             9093..9920
                     /gene="nadE"
                     /locus_tag="RHX21_001366"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HDV1986581.1"
                     /translation="MTLQQQIIKALGAKPQINAEEEIRRSVDFLKSYLRTYPFIKSLV
                     LGISGGQDSTLAGKLCQMAINELRQETGNESLQFIAVRLPYGVQADEQDCQDAIAFIQ
                     PDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMKAQYSIAGMTSGVVVGT
                     DHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLTALGCPEHLYKKAPTADLEDDR
                     PSLPDEVALGVTYDNIDDYLEGKNVPEQVARTIENWYLKTEHKRRPPITVFDDFWKK"
     gene            10150..11037
                     /gene="cho"
                     /locus_tag="RHX21_001367"
     CDS             10150..11037
                     /gene="cho"
                     /locus_tag="RHX21_001367"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease Cho"
                     /protein_id="HDV1986582.1"
                     /translation="MVRRLTSPRLEFEAAAIYEYPEHLRSFLNDLPTRPGVYLFHGES
                     DTMPLYIGKSINIRSRVLSHLRTPDEAAMLRQSRRISWICTAGEIGALLLEARLIKEQ
                     QPLFNKRLRRNRQLCALQLNEKRVDVVYAKEVDFSRAPNLFGLFANRRAALQALQSIA
                     DEQKLCYGLLGLEPLSRGRACFRSALKRCAGACCGKESHEEHALRLRQSLERLRVVCW
                     PWQGAVALKEQHPEMTQYHIIQNWLWLGAVNSLEEATTLIRTPAGFDHDGYKILCKPL
                     LSGNYEITELDPANDQRAS"
     gene            complement(10997..11572)
                     /gene="ves"
                     /locus_tag="RHX21_001368"
     CDS             complement(10997..11572)
                     /gene="ves"
                     /locus_tag="RHX21_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310475.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="environmental stress-induced protein Ves"
                     /protein_id="HDV1986583.1"
                     /translation="MEYFDMRKMSVNLWRNAAGETREICTFPPAKRDFYWRASIASIA
                     ANGEFSLFPGMERIVTLLEGGEMFLESADRFNHTLKPLQPFAFAADQVVKAKLTAGQM
                     SMDFNIMTRLDVCKAKVRIAERTFTTFGSRGGVVFVINGAWQLGDKLLTTDQGACWFD
                     GRHTLRLLQPQGKLLFSEINWLAGHSPDQVQ"
     gene            complement(11775..12260)
                     /gene="spy"
                     /locus_tag="RHX21_001369"
     CDS             complement(11775..12260)
                     /gene="spy"
                     /locus_tag="RHX21_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-independent periplasmic protein-refolding
                     chaperone"
                     /protein_id="HDV1986584.1"
                     /translation="MRKLTALFVASTLALGAANLAHAADTTTAAPADAKPMMHHKGKF
                     GPHQDMMFKDLNLTDAQKQQIREIMKGQRDQMKRPPLEERRAMHDIIASDTFDKAKAE
                     AQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQFNANFEKRLTERPAAKGKMPATA
                     E"
     gene            complement(12590..13558)
                     /gene="astE"
                     /locus_tag="RHX21_001370"
     CDS             complement(12590..13558)
                     /gene="astE"
                     /locus_tag="RHX21_001370"
                     /EC_number="3.5.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylglutamate desuccinylase"
                     /protein_id="HDV1986585.1"
                     /translation="MDNFLALTLTGKKPVITEREINGVRWRWLGDGVLELTPLTPPQG
                     ALVISAGIHGNETAPVEMLDALLGAISHGEIPLRWRLLVILGNPPALKQGKRYCHSDM
                     NRMFGGRWQLFAESGETCRARELEQCLEDFYDLGKESVRWHLDLHTAIRGSLHPQFGV
                     LPQRDIPWDEKFLTWLGAAGLEALVFHQEPGGTFTHFSARHFGALACTLELGKALPFG
                     QNDLRQFAVTASAIAALLSGESVGIVRTPPLRYRVVSQITRHSPSFEMHMASDTLNFM
                     PFEKGTLLAQDGEERFTVTHDVEYVLFPNPLVALGLRAGLMLEKIS"
     gene            complement(13551..14894)
                     /gene="astB"
                     /locus_tag="RHX21_001371"
     CDS             complement(13551..14894)
                     /gene="astB"
                     /locus_tag="RHX21_001371"
                     /EC_number="3.5.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-succinylarginine dihydrolase"
                     /protein_id="HDV1986586.1"
                     /translation="MNAWEVNFDGLVGLTHHYAGLSFGNEASTRHRFQVSNPRQAAKQ
                     GLLKMKALADAGFPQAVIPPHERPFIPVLRQLGFSGSDEQVLEKVARQAPHWLSSVSS
                     ASPMWVANAATIAPSADTLDGKVHLTVANLNNKFHRSLEAHVTESLLKAIFNDEEKFS
                     VHSALPQVALLGDEGAANHNRLGGHYGEPGMQLFVYGREEGNDTRPSRYPARQTREAS
                     EAVARLNQVNPQQVIFAQQNPDVIDQGVFHNDVIAVSNRQVLFCHQQAFARQSQLLAN
                     LRARVNGFMAIEVPATQVSVSDAVSTYLFNSQLLSRDDGSMMLVLPQECREHAGVWGY
                     LNELLAADNPISELKVFDLRESMANGGGPACLRLRVVLTEEERRAVNPAVMMNDTLFN
                     ALNDWVDRYYRDRLTAADLADPQLLRGGREALDVLSQLLNLGSVYPFQREGGGNG"
     gene            complement(14891..16369)
                     /gene="astD"
                     /locus_tag="RHX21_001372"
     CDS             complement(14891..16369)
                     /gene="astD"
                     /locus_tag="RHX21_001372"
                     /EC_number="1.2.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylglutamate-semialdehyde dehydrogenase"
                     /protein_id="HDV1986587.1"
                     /translation="MTLWINGDWITGQGASRVKRNPVSGEVLWQGNDADAAQVGQACR
                     AARAAFPRWARLSLAERQVVVERFAGLLERNKGELTAIIARETGKPRWEAATEVTAMI
                     NKIAISIKAYHVRTGEQRSEMPDGAASLRHRPHGVLAVFGPYNFPGHLPNGHIVPALL
                     AGNTIIFKPSELTPWSGEAVMRLWQQAGLPPGVLNLVQGGRETGQALSALEDLDGLLF
                     TGSANTGYQLHRQLSGQPEKILALEMGGNNPLIIDEVADIDAAVHLTIQSAFVTAGQR
                     CTCARRLLLKSGAQGDAFLARLVAVSQRLTPGNWDDEPQPFIGGLISEQAAQQVVTAW
                     QQLEAMGGRTLLAPRLLQSETSLLTPGIIEMTGVAGVPDEEVFGPLLRVWRYDSFEEA
                     ILMANNTRFGLSCGLVSPEREKFDQLLLEARAGIVNWNKPLTGAASTAPFGGIGASGN
                     HRPSAWYAADYCAWPMASLESDSLTLPATLNPGLDFSDEVVR"
     gene            complement(16366..17400)
                     /gene="astA"
                     /locus_tag="RHX21_001373"
     CDS             complement(16366..17400)
                     /gene="astA"
                     /locus_tag="RHX21_001373"
                     /EC_number="2.3.1.109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine N-succinyltransferase"
                     /protein_id="HDV1986588.1"
                     /translation="MMVIRPVERSDVSALMQLASKTGGGLTSLPANEATLSARIERAI
                     KTWQGELPKSEQGYVFVLEDSETGTVAGICAIEVAVGLNDPWYNYRVGTLVHASKELN
                     VYNALPTLFLSNDHTGSSELCTLFLDPDWRKEGNGYLLSKSRFMFMAAFRDKFNDKVV
                     AEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLS
                     QEAQDVIGQVHPQTAPARAVLEKEGFRYRNYIDIFDGGPTLECDIDRVRAIRKSRLVE
                     VAEGQPAQGDFPACLVANENYHHFRVVLARTDPATERLILTAAQLDALKCHAGDRVRL
                     VRLCAEEKTA"
     gene            complement(17397..18617)
                     /gene="astC"
                     /locus_tag="RHX21_001374"
     CDS             complement(17397..18617)
                     /gene="astC"
                     /locus_tag="RHX21_001374"
                     /EC_number="2.6.1.11"
                     /EC_number="2.6.1.81"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylornithine/acetylornithine transaminase"
                     /protein_id="HDV1986589.1"
                     /translation="MSQPITRENFDEWMIPVYAPAPFIPVRGEGSRLWDQQGKEYIDF
                     AGGIAVNALGHAHPELREALNEQASKFWHTGNGYTNEPVLRLAKKLIDATFADRVFFC
                     NSGAEANEAALKLARKFAHDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQPAYSQDFAP
                     LPADIRHAAYNDINSASALIDDSTCAVIVEPIQGEGGVVPASNAFLQGLRELCNRHNA
                     LLIFDEVQTGVGRTGELYAYMHYGVTPDLLTTAKALGGGFPVGALLATEECARVMTVG
                     THGTTYGGNPLASAVAGKVLELINTPEMLNGVKQRHDWFVERLNTINHRYGLFSEVRG
                     LGLLIGCVLNADYAGQAKQISQEAAKAGVMVLIAGGNVVRFAPALNVSEEEVTTGLDR
                     FAAACEHFVSRGSS"
     gene            19063..19869
                     /gene="xthA"
                     /locus_tag="RHX21_001375"
     CDS             19063..19869
                     /gene="xthA"
                     /locus_tag="RHX21_001375"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HDV1986590.1"
                     /translation="MKFVSFNINGLRARPHQLEAIVEKHQPDVIGLQETKVHDDMFPL
                     EEVAKLGYNVFYHGQKGHYGVALLTKETPIAVRRGFPGDDEEAQRRIIMAEIPSPLGN
                     VTVINGYFPQGESRDHPIKFPAKAQFYQNLQNYLETELKRDNPVLIMGDMNISPTDLD
                     IGIGEENRKRWLRTGKCSFLPEEREWMDRLMSWGLVDTFRHANPQTADRFSWFDYRSK
                     GFDDNRGLRIDLLLASQPLAECCVETGIDYEIRSMEKPSDHAPVWATFRR"
     gene            20036..20746
                     /locus_tag="RHX21_001376"
     CDS             20036..20746
                     /locus_tag="RHX21_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416264.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDV1986591.1"
                     /translation="MNAERKFLLACLIFALVIYAIHTFGLFDLLTDLPHLQTLIRQSG
                     LFGYSLYILLFIIATLFLLPGSILVIAGGIVFGPLLGTLLSLIAATLASSCSFLLARW
                     LGRDLLLKYVGHSHTFQAIEKGIARNGIDFLILTRLIPLFPYNIQNYAYGLTTIAFWP
                     YTLISALTTLPGIVIYTVMASDLANEGITLRFILQLCLAGLALFILVQLAKLYARHKH
                     VDLSASRRSPLTHPKNEG"
     gene            20751..21428
                     /gene="ydjY"
                     /locus_tag="RHX21_001377"
     CDS             20751..21428
                     /gene="ydjY"
                     /locus_tag="RHX21_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416265.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YdjY"
                     /protein_id="HDV1986592.1"
                     /translation="MSQHYSVSWKKGLAALCLLAVAGLSGCDQKENAAAKVEYDGLSN
                     SQPLRVDANNHTVTMLVQINGRFLTDDTRHGIVFKDGSNGHKSLFMAYATPKAFYEAL
                     KEAGGTPGENMTMDNKETTHVTGSKLDISVNWQGAAKAYSFDEVIVDSNGKKLDMRFG
                     GNLTAAEEKKTGCLVCLDSCPVGIVSNATYTYGAVEKRGEVKFKGNASVLPADNTLAT
                     VTFKITE"
     gene            21443..22150
                     /locus_tag="RHX21_001378"
     CDS             21443..22150
                     /locus_tag="RHX21_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDV1986593.1"
                     /translation="MMKIQSRKIWYYRITLIILLFAMLLAWALLPGVHEFINRSVAAF
                     AAVDQQGIERFIQSYGALAAVVSFLLMILQAIAAPLPAFLITFANASLFGAFWGGLLS
                     WTSSMAGAALCFFIARVMGREVVEKLTGKTVLDSMDGFFTRYGKHTILVCRLLPFVPF
                     DPISYAAGLTSIRFRSFFIATGLGQLPATIVYSWAGSMLTGGTFWFVTGLFILFALTV
                     VIFMAKKIWLERQKRNA"
     gene            22150..22698
                     /locus_tag="RHX21_001379"
     CDS             22150..22698
                     /locus_tag="RHX21_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HDV1986594.1"
                     /translation="MGLPPLSKIPFILRPQAWLHRRHYGEVLSPIRWWGRIPFIFYLV
                     SMFVGWLERKRSPLDPVVRSLVSARIAQMCLCEFCVDITSMKVAERTGSTDKLLAVAD
                     WRQSPLFSDEERLALEYAEAASVTPPTVDDALRTRLAAHFDAQALTELTALIGLQNLS
                     ARFNSAMDIPAQGLCRIPEKRS"
     gene            22708..23874
                     /locus_tag="RHX21_001380"
     CDS             22708..23874
                     /locus_tag="RHX21_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416268.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDV1986595.1"
                     /translation="MRHCGWLLGLLSLFSLATHASDWQEIKNEAKGQTVWFNAWGGDT
                     AINRYLDWVSGEMKTHYAINLKIVRLADAADAVKRIQTEAAAGRKTGGSVDLLWVNGE
                     NFRTLKEANLLQTGWAETLPNWRYVDTQLPVREDFSVPTEGAESPWGGAQLTFIARRD
                     VTPQPPQTPQALLEFAKANPGTVTYPRPPDFTGTAFLEQLLIMLTPDPAALKVAPDKA
                     TFARVTAPLWQYLDALHPYLWRKGKDFPPSPARMDALLKAGTLRLSLTFNPAHAQQKI
                     ASGDLPASSYSFGFNQGMIGNVHFVTIPANANASAAAKVVANFLLSPNAQLRKADPAV
                     WGDPSVLDPQKLPDGQRETLQSRMPQDLPPVLAEPHAGWVNALEQEWLHRYGTH"
     gene            23847..25382
                     /locus_tag="RHX21_001381"
     CDS             23847..25382
                     /locus_tag="RHX21_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310488.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDV1986596.1"
                     /translation="MATPLRYALIFLLWAMVAVIYAPLIPAALTLISPALSLTHWQAL
                     FADPQLPQALLATLVSTTIAAVGALLIALLVIVALWPWPKWQRMCARLPWLLAIPHVA
                     FATSALLLFAEGGLLYDYFPYFTPLMDKLGIGLGLTLAVKESAFLLWILAAVLSEKRL
                     LQQVIVLDSLGYSRWQCLNWLLLPSVAPALAMAMLAIVAWSLSVVDVAIILGPGNPPT
                     LAVISWQWLTQGDADQQTKGALASLLLMLLLAAYVLLSYLLWRSWRRTIPRVDGIRKP
                     ATPLLPGTTLASFLPLTGVLCVVLLAILADQSTINSEALINSLTMGLVATFIALLLLL
                     LWLEWGPQRRQLWLWLPILLPALPLVAGQYTLALWLNLDGSWTAVVWGHLLWVMPWML
                     FILQPAWQRIDSRLILIAQTLSWSRAKIFFYVKCPLMLRPTLIAFAVGFSVSIAQYMP
                     TLWLGAGRFPTLTTEAVALSSGGSNGIFAAQALWQLLLPLIIFALTALVAKWVGYVRQ
                     GLR"
     gene            25382..26035
                     /locus_tag="RHX21_001382"
     CDS             25382..26035
                     /locus_tag="RHX21_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDV1986597.1"
                     /translation="MLCVKNVSLRLPESRLLTNVNFTVDKGDIVTLMGPSGCGKSTLF
                     SWMIGALAGQFSCTGELWLNEQRIDMLPTAQRQIGILFQDALLFDQFSVGQNLLLALP
                     STLKGTARRNAVKDALDRAGLAETYHQDPATLSGGQRARVALLRALLAQPKALLLDEP
                     FSRLDVALRDSFRQWVFSEVRELAIPVVQVTHDLQDVPADSSVLDMAQWSENYNKLR"
     gene            26102..27409
                     /gene="ynjE"
                     /locus_tag="RHX21_001383"
     CDS             26102..27409
                     /gene="ynjE"
                     /locus_tag="RHX21_001383"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310490.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase YnjE"
                     /protein_id="HDV1986598.1"
                     /translation="MKRVSQMTALAMALGLACASSWAAELAKPLTLDQLQQQNGKAID
                     TRPSAFYNGWPQTLNGPSGHEPAALNLSASWLDKMSTEQLNAWIKQHNLKADAPVALY
                     GNGKDVDAVKTRLQKAGFTHISILSDALSEPSRLQKLPHFEQLVYPQWLHDLQQGKEV
                     TAKPAGDWKVIEAAWGAPKFYLISHIPGADYIDTNEVESEPLWNKVSDEQLKAMLAKH
                     GIRHDTTVILYGRDVYAAARVAQIMLYAGVKDVRLLDGGWQTWSDAGLPVERGTPPKV
                     KAEPDFGVKIPAQPQLMLDMEQARGLLHRQDASLVSIRSWPEFIGTTSGYSYIKPKGE
                     IAGARWGHAGSDSTHMEDFHNPDGTMRSADDITAMWKAWNIKPDQQVSFYCGTGWRAS
                     ETFMYARAMGWKNVSVYDGGWYEWSSDPKNPVATGERGPDSSK"
     gene            complement(27418..28038)
                     /locus_tag="RHX21_001384"
     CDS             complement(27418..28038)
                     /locus_tag="RHX21_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707357.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HDV1986599.1"
                     /translation="MLDRHLHPRIKPLLHQCVRVLDKPGITPDGLTLVGFAIGVLALP
                     FLALGWYLAALVVILLNRLLDGLDGALARRRGLTDAGGFLDISLDFLFYALVPFGFIL
                     AAPQQNALAGGWLLFAFIGTGSSFLAFAALAAKHQIDNPGYAHKSFYYLGGLTEGTET
                     ILLFVLGCLFPAWFAWFAWIFGALCWMTTFTRVWSGYLTLKSHQRQ"
     gene            28125..28532
                     /gene="nudG"
                     /locus_tag="RHX21_001385"
     CDS             28125..28532
                     /gene="nudG"
                     /locus_tag="RHX21_001385"
                     /EC_number="3.6.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP pyrophosphohydrolase"
                     /protein_id="HDV1986600.1"
                     /translation="MKMIEVVAAIIERDGKILLAQRPAQSDQAGLWEFAGGKVEPDES
                     QRQALVRELREELGIEATVGEYVTSHQREVSGRIIHLHAWHVPDFHGTLQAHEHQALV
                     WCSPEEALQYPLAPADIPLLEAFMALRAARPAD"
     gene            complement(28498..28770)
                     /locus_tag="RHX21_001386"
     CDS             complement(28498..28770)
                     /locus_tag="RHX21_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnjH family protein"
                     /protein_id="HDV1986601.1"
                     /translation="MSRALFAVVLAFPLIALANPHYRPDVEVNVPPEVFSSGGQSAQP
                     CTQCCVYQDKNYSEGAVIKAEGILLQCQRDDKTLSTNPLVWRRVKP"
     gene            29006..30349
                     /gene="gdhA"
                     /locus_tag="RHX21_001387"
     CDS             29006..30349
                     /gene="gdhA"
                     /locus_tag="RHX21_001387"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HDV1986602.1"
                     /translation="MDQTYSLESFLNHVQKRDPNQTEFAQAVREVMTTLWPFLEQNPK
                     YRQMSLLERLVEPERVIQFRVVWVDDRNQVQVNRAWRVQFSSAIGPYKGGMRFHPSVN
                     LSILKFLGFEQTFKNALTTLPMGGGKGGSDFDPKGKSEGEVMRFCQALMTELYRHLGA
                     DTDVPAGDIGVGGREVGFMAGMMKKLSNNTACVFTGKGLSFGGSLIRPEATGYGLVYF
                     TEAMLKRHGMGFEGMRVSVSGSGNVAQYAIEKAMEFGARVITASDSSGTVVDESGFTK
                     EKLARLIEIKASRDGRVADYAKEFGLVYLEGQQPWSVPVDIALPCATQNELDVDAAHQ
                     LIANGVKAVAEGANMPTTIEATELFQQAGVLFAPGKAANAGGVATSGLEMAQNAARLG
                     WKAEKVDARLHHIMLDIHHACVEHGGEGEQTNYVQGANIAGFVKVADAMLAQGVI"
     gene            complement(30466..31506)
                     /locus_tag="RHX21_001388"
                     /pseudo
     CDS             complement(30466..31506)
                     /locus_tag="RHX21_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416276.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
     gene            complement(31634..33595)
                     /gene="topB"
                     /locus_tag="RHX21_001389"
     CDS             complement(31634..33595)
                     /gene="topB"
                     /locus_tag="RHX21_001389"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDV1986603.1"
                     /translation="MRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGH
                     LLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHEASEIVHAG
                     DPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAIDRLRSNSEFVPLCV
                     SALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVA
                     KDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRISGQPAIV
                     TSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCR
                     YLPEEHFAGRHAVMNAISVHAPDLLPQPVVDPDIRNRCWDDKKVDAHHAIIPTARSSA
                     INLTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDIAKGKFVAKARFLAEAGWRTLL
                     GSKERDEENDGTPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQ
                     DKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHSLPEMAT
                     RPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTPVRQFRGIVAPGSGG
                     SADKKKAAPRKRSAKKSPPADEVGSGAIA"
     gene            complement(33600..34643)
                     /gene="selD"
                     /locus_tag="RHX21_001390"
     CDS             complement(33600..34643)
                     /gene="selD"
                     /locus_tag="RHX21_001390"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HDV1986604.1"
                     /translation="MSENSIRLTQYSHGAGCGCKISPKVLETILHSEQAKFVDPNLLV
                     GNETRDDAAVYDLGNGTSVISTTDFFMPIVDNPFDFGRIAATNAISDIFAMGGKPIMA
                     IAILGWPINKLSPEIAREVTEGGRYACRQAGIALAGGHSIDAPEPIFGLAVTGIVPTE
                     RVKKNSTAQAGCKLFLTKPLGIGVLTTAEKKSLLKPEHQGLATEVMCRMNIAGASFAN
                     IEGVKAMTDVTGFGLLGHLSEMCQGAGVQARVDYDAIPKLPGVEEYIKLGAVPGGTER
                     NFASYGHLMGEMPREVRDLLCDPQTSGGLLLAVMPEAENEVKTTAAEFGIELTAIGEL
                     VPARGGRAMVEIR"
     gene            complement(34760..35311)
                     /locus_tag="RHX21_001391"
     CDS             complement(34760..35311)
                     /locus_tag="RHX21_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H nitroreductase"
                     /protein_id="HDV1986605.1"
                     /translation="MDALELLINRRSASRLAEPAPTGEQLQNILRAGMRAPDHKSMQP
                     WHFFVIEGEGRERFSAVLEQGAIAAGSDDKAIDKARNAPFRAPLIITVVAKCEENHKV
                     PRWEQEMSAGCAVMAMQMAAVAQGFGGIWRSGALTESPVVREAFGCREQDKIVGFLYL
                     GTPQLKASTSINVPDPTPFVTYF"
     gene            35472..37328
                     /gene="sppA"
                     /locus_tag="RHX21_001392"
     CDS             35472..37328
                     /gene="sppA"
                     /locus_tag="RHX21_001392"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707347.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HDV1986606.1"
                     /translation="MRTLWRFIAGFFKWTWRLLNFVREMVLNLFFIFLVLVGVGIWMQ
                     VSGGDSKETASRGALLLDISGVIVDKPDSSQRFSKLSRQLLGASSDRLQENSLFDIVN
                     TIRQAKDDRNITGIVMDLKNFAGGDQPSMQYIGKALKEFRDSGKPVYAVGENYSQGQY
                     YLASFANKIWLSPQGVVDLHGFATNGLYYKSLLDKLKVSTHVFRVGTYKSAVEPFIRD
                     DMSPAAREADSRWIGELWQNYLNTVAANRLIPAQQVFPGAQGLLVGLTKTGGDTAKYA
                     LENKLVDALASSAEIEKALTKEFGWSKTDKNYRAISYYDYALKTPADTGDSIGVVFAN
                     GAIMDGEETQGNVGGDTTAAQIRDARLDPKVKAIVLRVNSPGGSVTASEVIRAELAAA
                     RAAGKPVVVSMGGMAASGGYWISTPANYIVANPSTLTGSIGIFGVITTVENSLDSIGV
                     HTDGVSTSPLADVSITRALPPEAQQMMQLSIENGYKRFITLVADARHSTPEQIDKIAQ
                     GHVWTGQDAKANGLVDSLGDFDDAVAKAAELAKVKQWHLEYYVDEPTFFDKVMDNMSG
                     SVRAMLPDAFQAMLPAPLASVASTVKSESDKLAAFNDPQNRYAFCLTCANVR"
     gene            37495..38511
                     /gene="ansA"
                     /locus_tag="RHX21_001393"
     CDS             37495..38511
                     /gene="ansA"
                     /locus_tag="RHX21_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HDV1986607.1"
                     /translation="MQKKSIYVAYTGGTIGMQRSEQGYIPVSGHLQRQLALMPEFHRP
                     EMPDFTIHEYTPLMDSSDMTPEDWQHIAEDIKAHYDDYDGFVILHGTDTMAYTASALS
                     FMLENLGKPVIVTGSQIPLAELRSDGQINLLNALYVAANYPINEVTLFFNNRLYRGNR
                     TTKAHADGFDAFASPNLPPLLEAGIHIRRLNTPPAPHGEGELIVHPITPQPIGVVTIY
                     PGISADVVRNFLRQPVKALILRSYGVGNAPQNKAFLQELQEASDRGIVVVNLTQCMSG
                     KVNMGGYATGNALAHAGVIGGADMTVEATLTKLHYLLSQELDTETIRKAMSQNLRGEL
                     TPDD"
     gene            38522..39163
                     /gene="pncA"
                     /locus_tag="RHX21_001394"
     CDS             38522..39163
                     /gene="pncA"
                     /locus_tag="RHX21_001394"
                     /EC_number="3.5.1.-"
                     /EC_number="3.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310502.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional nicotinamidase/pyrazinamidase"
                     /protein_id="HDV1986608.1"
                     /translation="MPPRALLLVDLQNDFCAGGALAVPEGDSTVDVANRLIDWCQSRG
                     EAVIASQDWHPANHGSFASQHCVEPYMPGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQ
                     KAIAAVFHKGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFT
                     VLDALQLGYKVNVITDGCRGVNIQPQDSAHAFMEMSAAGATLYTLADWEETQG"
     gene            complement(39324..39596)
                     /locus_tag="RHX21_001395"
     CDS             complement(39324..39596)
                     /locus_tag="RHX21_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707337.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeaC family protein"
                     /protein_id="HDV1986609.1"
                     /translation="MNLDDIINSMTPEVYQRLSTAVELGKWPDGVALTEEQKENCLQL
                     VMLWQARHNTEAQHMTIDTNGQMVMKSKQQLKEDFGISAKPIAMFK"
     gene            complement(39638..40051)
                     /gene="msrB"
                     /locus_tag="RHX21_001396"
     CDS             complement(39638..40051)
                     /gene="msrB"
                     /locus_tag="RHX21_001396"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HDV1986610.1"
                     /translation="MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVY
                     HCLICDAPLFHSETKYDSGCGWPSFYEPVSEESIRYIKDLSHGMQRIEIRCGNCDAHL
                     GHVFPDGPQPTGERYCVNSASLRFTDGENGEEING"
     gene            40393..41388
                     /gene="gapA"
                     /locus_tag="RHX21_001397"
     CDS             40393..41388
                     /gene="gapA"
                     /locus_tag="RHX21_001397"
                     /EC_number="1.2.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006322611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDV1986611.1"
                     /translation="MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYM
                     LKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLT
                     DETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAK
                     VINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKV
                     LPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTE
                     DDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK"
     gene            41472..42356
                     /locus_tag="RHX21_001398"
     CDS             41472..42356
                     /locus_tag="RHX21_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707334.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-hexose-6-phosphate mutarotase"
                     /protein_id="HDV1986612.1"
                     /translation="MIKKIFALPVIEQISPVLSRRKLDELDLIVVDHPQVKASFALQG
                     AHLLSWKPAGEEEVLWLSNNTPFKNGVAIRGGVPVCWPWFGPAAQQGLPAHGFARNLP
                     WTLKSHREDADGVALTFELTQSEETKKFWPHDFTLLAHFRVGKTCEIDLESHGEFETT
                     SALHTYFNVGDIAKVSVSGLGDRFIDKVNDAKEDVLTDGIQTFPDRTDRVYLNPQDCS
                     VINDEALNRIIAVGHQHHLNVVGWNPGPALSVSMGDMPDDGYKTFVCVETAYASETQK
                     VTKEKPAHLAQSIRVAKR"
     gene            complement(42407..43261)
                     /gene="yeaE"
                     /locus_tag="RHX21_001399"
     CDS             complement(42407..43261)
                     /gene="yeaE"
                     /locus_tag="RHX21_001399"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal reductase YeaE"
                     /protein_id="HDV1986613.1"
                     /translation="MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIEL
                     GLTLIDTAEMYADGGAEKVVGEALTGLRDNVFLVSKVYPWNAGGQKAINACEASLRRL
                     NTDYLDLYLLHWSGSFAFEETVAAMEKLIAQGKIRRWGVSNLDHADMQELWQLPGGNQ
                     CATNQVLYHLGSRGIEYDLLPWCQQQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHA
                     HNISAAQVLLAWVISHQGVMAIPKAATIAHVQQNAAVLEVELSSAELTMLDKAYPAPK
                     GKTALDMV"
     gene            complement(43351..44097)
                     /gene="mipA"
                     /locus_tag="RHX21_001400"
     CDS             complement(43351..44097)
                     /gene="mipA"
                     /locus_tag="RHX21_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="scaffolding protein MipA"
                     /protein_id="HDV1986614.1"
                     /translation="MTKLKLLALGVLIATSAGVAHAEGKFSLGAGVGVVEHPYKDYDT
                     DVYPVPVINYEGDNFWFRGLGGGYYLWNDATDKLSITAYWSPLYFKAKDSGNHQMRHL
                     DDRKSTMMAGLSYAHFTQYGYLRTTLAGDTLDNSNGIVWDMAWLYRYTNGGLTVTPGI
                     GVQWNSENQNEYYYGVSRKESARSGLRGYNPNDSWSPYLELSASYNFLGDWSVYGTAR
                     YTRLSDEVTDSPMVDKSWTGLISTGITYKF"
     gene            44533..46467
                     /gene="yeaG"
                     /locus_tag="RHX21_001401"
     CDS             44533..46467
                     /gene="yeaG"
                     /locus_tag="RHX21_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase YeaG"
                     /protein_id="HDV1986615.1"
                     /translation="MNIFDHYRQRYEAAKDEEFTLQEFLTTCRQDRSAYANAAERLLM
                     AIGEPVMVDTAQEPRLSRLFSNRVIARYPAFEEFYGMEDAIEQIVSYLKHAAQGLEEK
                     KQILYLLGPVGGGKSSLAERLKSLMQLVPIYVLSANGERSPVNDHPFCLFNPQEDAQI
                     LEKEYGIPRRYLGTIMSPWAAKRLHEFGGDITKFRVVKVWPSILQQIAIAKTEPGDEN
                     NQDISALVGKVDIRKLEHYAQNDPDAYGYSGALCRANQGIMEFVEMFKAPIKVLHPLL
                     TATQEGNYNGTEGISALPFNGIILAHSNESEWVTFRNNKNNEAFLDRVYIVKVPYCLR
                     ISEEIKIYEKLLNHSELTHAPCAPGTLETLSRFSILSRLKEPENSSIYSKMRVYDGES
                     LKDTDPKAKSYQEYRDYAGVDEGMNGLSTRFAFKILSRVFNFDHVEVAANPVHLFYVL
                     EQQIEREQFPQEQAERYLEFLKGYLIPKYAEFIGKEIQTAYLESYSEYGQNIFDRYVT
                     YADFWIQDQEYRDPDTGQLFDRESLNAELEKIEKPAGISNPKDFRNEIVNFVLRARAN
                     NSGRNPNWTSYEKLRTVIEKKMFSNTEELLPVISFNAKTSTDEQKKHDDFVDRMMEKG
                     YTRKQVRLLCEWYLRVRKSS"
     gene            46580..47863
                     /locus_tag="RHX21_001402"
     CDS             46580..47863
                     /locus_tag="RHX21_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeaH/YhbH family protein"
                     /protein_id="HDV1986616.1"
                     /translation="MTWFIDRRLNGKNKSMVNRQRFLRRYKAQIKQSISEAINKRSVT
                     DVDSGESVSIPTEDISEPMFHQGRGGLRHRVHPGNDHFVQNDRIERPQGGGGGSGSGQ
                     GQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKQNQQRQLTEYKTHRAGYTANGV
                     PANISVVRSLQNSLARRTAMTAGKRRELHALEENLAIISNSEPAQLLEEERLRKEIAE
                     LRAKIERVPFIDTFDLRYKNYEKRPDPSSQAVMFCLMDVSGSMDQSTKDMAKRFYILL
                     YLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYNP
                     AQWNIYAAQASDGDNWADDSPLCHEILAKKLLPVVRYYSYIEITRRAHQTLWREYEHL
                     QSTFDNFAMQHIRDQDDIYPVFRELFHKQNATAKD"
     gene            48010..>48206
                     /locus_tag="RHX21_001403"
     CDS             48010..>48206
                     /locus_tag="RHX21_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDV1986617.1"
                     /translation="MIQSTRISMGLFFKYFLSLTKIDPGQNYISLPSIKSSTHIALLF
                     MVSMGTQKLKAQSFFIFSLLLT"
BASE COUNT        11935 a        12600 c        11819 g        11852 t
ORIGIN      
        1 tctcatttaa atctaagtca cttacaatat aagtttaaga gcgacgccac aggatgaact
       61 atcaaaaata gctcatcatg attagcaaaa cttaaccatt ttaaaataaa taaacaatta
      121 aagaaaaaag atcacttatt tatagcaata gctcgtcaaa ggcagctttt tgttacaggt
      181 ggtttgaatg aatgtagcaa cgaaatgcag aatttcaggt catgtaactc ccggcaaaac
      241 cgggaggtat gtaatcctta ctcagtcact tccccttcct ggcggatctg atttgcccaa
      301 cgttgggcag attcaggcac agtaaacgcc ggtgagcgca gaaatgactc tcccatcagt
      361 acaaacgcaa catatttgct acgcagcatc cagacatcac gaaacgaatc catctttatc
      421 gcatgttctg gcggcgcggg ttccgtgcgt gggacatagc taataatctg gcggttttgc
      481 tggcggagcg gtttcttcat tactggcttc actaaacgca tattaaaaat tagaaaaact
      541 gtagtttagc cgatttagcc cctgtacgtc ccgctttgcg tgtatttcat aacaccgttt
      601 ccagaatagt ctccgaagcg ggatctggct ggtgatctat agttagagag ttttttgacc
      661 aaaacagcgg ccctttcagt aataaattaa ggagacgagt tcaatgtcgc aacataacga
      721 aaagaaccca catcagcacc agtcaccact acacgattcc agcgaagcga aaccggggat
      781 ggactcactg gcacctgagg acggatctca tcgtccagcg gctgaaccaa caccgccagg
      841 tgcacaacct accgcccctg ggagcctgaa agcccctgat acacgtaacg aaaaacttaa
      901 ttctctggaa gacgtacgca aaggcagtga aaattatgcg ctgaccacta atcagggcgt
      961 gcgcatcgcc gatgatcaaa actcactgcg tgccggtaac cgtggtccaa cgctgctgga
     1021 agattttatt ctgcgcgaga aaatcaccca ctttgaccat gagcgcatcc cggaacgtat
     1081 tgttcatgca cgcggatcag cagctcacgg ttatttccag ccatataaaa gcttaagcga
     1141 tatcaccaaa gcggatttcc tctcagatcc gaacaaaatc accccagtat ttgttaggtt
     1201 ctctaccgtt cagggtggcg ctggctctgc cgataccgtg cgtgatatcc gtggttttgc
     1261 caccaagttc tatactgaag agggtatttt tgacctcgtt ggcaataaca cgccaatctt
     1321 ctttatccag gatgcgcata aattccccga ttttgttcat gcggtaaaac cagaaccaca
     1381 ctgggcaatt ccacaagggc aaagcgccca cgatactttc tgggattatg tttctctgca
     1441 acctgaaact ctgcacaacg tgatgtgggc gatgtcggat cgcggcatcc cccgcagtta
     1501 ccgcaccatg gaaggcttcg gtattcacac cttccgcctg attaatgccg aagggaaggc
     1561 aacgtttgta cgtttccact ggaaaccact ggcaggtaaa gcctcactcg tttgggatga
     1621 agcacaaaaa ctcaccggac gtgacccgga cttccaccgc cgcgagttgt gggaagccat
     1681 tgaagcaggc gattttccgg aatacgaact gggcttccag ttgattcctg aagaagatga
     1741 attcaagttc gacttcgatc ttctcgatcc aaccaaactg atcccggaag aactggtgcc
     1801 cgttcagcgt gtcggcaaaa tggtgctcaa tcgcaatccg gataacttct ttgccgaaaa
     1861 cgaacaagca gcattccatc caggtcatat tgttcctggt ctggacttca ccaacgatcc
     1921 gctgttgcag ggacgtttgt tctcctatac cgatacacaa atcagtcgtc ttggtgggcc
     1981 gaatttccat gagattccga ttaaccgtcc gacctgccct taccacaact tccagcgtga
     2041 tggcatgcat cgtatgggga tcgacactaa cccggcgaat tacgaaccga actcgatcaa
     2101 cgataactgg ccgcgcgaaa caccgccggg accgaaacgc ggcggttttg aatcatatca
     2161 ggaacgcgtg gaaggaaata aagttcgtga gcgcagtcca tcgtttggcg aatattattc
     2221 ccatccgcat ctgttctggc taagtcagac gccattcgag cagcgccata ttgtcgatgg
     2281 tttcagtttt gagttaagca aagtcgttcg tccgtatatt cgtgagcgcg ttgttgacca
     2341 gctggcgcat attgatctca ctctggccca ggcggtggcg aaaaatctcg gtatcgaact
     2401 gactgacgac cagctgaata tcaccccacc tccggacgtc aacggtctga aaaaggatcc
     2461 atccttaagt ttgtacgcca ttcctgacgg tgatgtgaaa ggtcgcgtgg tagcgatttt
     2521 acttaatgat gaagtgagat cggcagacct tctggccatt ctcaaggccc tgaaggccaa
     2581 aggcgttcat gccaaactgc tctactcccg aatgggtgaa gtgactgcgg atgacggtac
     2641 ggtgttgcct atagccgcta cctttgccgg tgcaccttcg ctgacggtcg atgcggtcat
     2701 tgtcccttgc ggcaatatcg cggatatcgc tgacaacggc gatgccaact actacctgat
     2761 ggaagcctac aaacacctta aaccgattgc gctggcggga gacgcgcgca agtttaaagc
     2821 aacaatcaag gtcgctgacc agggtgaaga agggattgtg gaagctgaca gcgctgacgg
     2881 tagttttatg gatgaactgc taacgctgat ggcagcacac cgcgtgtggt cacgcattcc
     2941 taagattgac aaaattccgg cgtaaatatg gataaggtca cgtcccctgg ggagtgacct
     3001 taccacctta cttacacatc aagataacta cccaaccgat aaccacgctc agcaattgca
     3061 tatttcaacg acgctgatgt cagcacttcc agctccgtta accgtgggaa acagtaagca
     3121 ctcttgcgaa tcaaattatc gacaaacgcc ggatggcaca tgacttccag cgagcgttcc
     3181 ctgcgatggc tggaatcatc cagcacttgc aggaacagtg cctcgctaat ctcttcacca
     3241 taaaacgcgc tactgaatcc ctgcgaactg cgcagattag ccggtaaatc accagcgtta
     3301 gatagcggct gacggtcgat gcgcaacgca atcccctctt cagccgcaaa cctgacaaca
     3361 atcgggaaaa tctgcgggaa catatgcaca tgatgatggc tatcaagatg cgtaggtttg
     3421 cgtccaaata gctcaatgaa acgcaaatac tgactggcaa gctcctgagt aatttcttcc
     3481 agcggtaaag catcttcttc tgccaactgc cagatccatt ttcccagcac accatcgcgg
     3541 gttaaccccg gcatagctgt cagtggcttg cccatagtaa ggacaaagtg catccctatg
     3601 gccagactcg gttcatcacg actcaactgc accgcatggt caatagcctg cccattcacc
     3661 agcgccgtcg tcgatgtgac aatcccattg cgacaggcct cgataatgcc gtagttctga
     3721 cctttgctta agccaaaatc atcggcatta acaatcagta agcgttccat aatcagcctc
     3781 ggttaatgtg cttttttaag ctctgcgatg cagtcggcaa aatttggcag ccatttctcg
     3841 tgcgccagaa tcatctcgcg tgccagcagc tcagcatcgc gatcggaatg caccaacgga
     3901 ctaaggttta gcgccagtaa cacatcgtta aattctccgc taagtgcggc gttgctggca
     3961 gcaatctcga agcctttaat ggtgtgaatc agccccatca ctttatcatc gaaatgcgta
     4021 atgcgcggat gtggcgtcgc gccatcgcgc cccagcttac aggtcatttc taccgcccag
     4081 tctgccggaa tattatcaat atgcccatga tgcgggatat taacgtaatg ttcagcttgc
     4141 ttgtcgttgt agatagcgtt gatcacttcg cacgctgcat cagagtaata agccccaccg
     4201 cgctgttcca gttctttcgg cttaactttc aactccggat ttttatacag ctcaaaaagt
     4261 tgtttctcga ctttctgtac tacctgtgct cgtgcgccgc ctttgtagta ttcgcccatt
     4321 tcaatagcca gcatctcttt ctgcttgaag taatacagca gataagaaca tggcagcaga
     4381 tttaacgaac gaattaagcc ctcactaaat ggcagatcga aaatattttt tacagaggac
     4441 gcttttaact gccctgacgc cacaccatca agcaattcgg caaagcgcga cttgccattt
     4501 accagcacat ccttaatgaa caccatatgg ttgaggccga acagatcgat agataaatca
     4561 tcgctgtctt tcagcatcag aacatcgcga ataaacatct tcatgccgat cggaatatta
     4621 cacacgccga taaagcgttt aaatccggta tgacgataaa cggcttcagt gaccattccc
     4681 gccgggttag tgaagttaat cacccatgca ttcggacaaa gttcttcgac atcttttacg
     4741 atgtcaaaaa tcaccggaat ggtacgcaga cctttaaaca gaccgcccgc gccgttggtt
     4801 tcctgaccaa gataaccatg acttaatgga atacgttcat ccagttcgcg cgccggtaat
     4861 tggcctacgc gcagttgggt agtaacgaaa tcagcatctt tcaatgcttc gcggcgatcc
     4921 agcgttttat aaagcttcat cgggacgcca gcgttatcaa tcatccgttg gcagagttca
     4981 aaaatgatat ccagtttctc tttaccatct tcgacatcca ccagccataa ttcgctgacc
     5041 ggcaattcgt gataacgctt aataaatcct tccagtaact ccggggtata gctgctcccg
     5101 ccaccaatag tgacgacttt taatttctgg ctcataattt ctcccttcag tacagaatac
     5161 tgatatctgg catatctgcc cccccggaca taaataatcc agcaacagta cagatatgtg
     5221 aattgtcagg tataacgact tactgattaa attcagtcaa tttcttacga tagctcttag
     5281 gcgtaaagga cgttaatttc ttaaacgttt taataaacaa actcgggcta ctataaccgg
     5341 cctcaaacgc aatatccgtc acggaatagt tggtcatttc cagttgtttt ttggcaaaat
     5401 taatacggat ctcattaata atctgcattg gtgttttgcc ataatatcgt tgagtcgctc
     5461 gcgtcaaata ttcctgtgat ttggctgaca acgtcaccat attctccagc gccgattcac
     5521 taaactgctc tttatcatgc atcttttcta ccgtactttt cagccactgc ggtacatcat
     5581 caatcacctg ttcttcgcgg taatgacgta aacggttaat gacataaaaa gtaaccatct
     5641 caacaaactc ttccagccct gtttcgcgga aattcaatga agaaatcact gtttccacat
     5701 aggtgagaaa agcgttattg gtccggtata cctgcgaagc gacaaagcaa taaggcaaca
     5761 acggcaggta atgctgctca aaaaagcgtt tactgatccc aacgttcaat atacgcgtgg
     5821 caccaaactc ataaaaactt tgatggtgcg aacctaacgg aataaaaaca aaatcgcccc
     5881 gttccagtaa cacgcgctta ccgttaatct cctggaaata acgcccggtt aataccagag
     5941 taaattcata atagtcgtgc tgatgcagcc cgctgatact ctcagttttg ttatagataa
     6001 acacatggaa gtttttgcca ttaaacaact gctgttctcg ggcagtggca atttccggcg
     6061 cgttaatcac tggctgcatc atcgactcct tatgccttca gtttttcatg aagctcaatt
     6121 aattcagtaa tcagttcacg cgcaagcatg gacgtcatta aatgatcctg agcgtggacc
     6181 agcaccagac tcactttaat cttaccttcg cccgcatcgc cttcaatcag tttcgtctgt
     6241 accagatgcg cttcattcaa tgccatccgt gactgatcca tcatggcttt tgctgcagca
     6301 aaatcgccct gcttcgcctg tttcagtgcc gcatacgcca ggctgcgcgc ttgtccggag
     6361 ttgatgataa gccccatcac cacttcttcc agctcttcag cttctgtttg cgtatcagga
     6421 atattatcga gatccatcat acatcgttcc tctctcttct taccggcacg attacccgta
     6481 ccggcatcga ttaaaatttc agggcgttag cgatatcttc ttcgctttct tctttatcaa
     6541 tcgcattttg tgctttgtta gccaccacaa caaagggcag ataaattaac gttgcgatgc
     6601 caaggttgaa gagtgcgacc agcaatgcgg cgacgctacc gttggtgtta aagaaggctc
     6661 ccagaccggt tggcatggtc cacggtgcaa tattggtcac cggaggaata atgcccatgt
     6721 agtacgctgc gagggtgatt gccgccagaa tcggttgtac cagtacaaac gggataaaca
     6781 tcaccgggtt catgataatt ggcagaccaa acagaatcgg ttcgttaatc tggaagatgc
     6841 cggacggcag cgccagtttt gccacctgac gataatcagc acggcgagat gcgataaaga
     6901 tagccaggat caggcctaaa gtcgcaccac tgccaccgag gaaaataaag gagtccagca
     6961 tcggcttggc ccagatatgg aaggtcttac cggctgccag cgccgcttcg acggaaccat
     7021 attgctgata ggtcgcgata ttttccagcg cccacggcgt cataatgccg ttgtccagtg
     7081 cggtcagcgc cagcgcgcca tgaataccga agaaccagag cagtggaaca aagatcacat
     7141 aggcccagcc caccacgcta cccaacgatg ccagtggggt tgagatggta tccataatga
     7201 tctgatggaa gttggtgccc caggtattca acgcccaggc aataatcccc atcacggaaa
     7261 gaataataaa gccgggaatt aatgccgaga aggaacgcga tactgaagca ggtacgctgt
     7321 cgggcagttt aatgacccaa ttgcggcgga caataaaggt aaacatttct gccaccacca
     7381 ggccaataat aatcccggag atgatattcg ccccacctaa ccagtttgcg ccaaccgcat
     7441 aggcctcacc gacactatat ggggtgacgg tcataaatgc tgcaacggat aacaacccgg
     7501 ccgccagcgc atcgacttta cgctcttctg ccagcgccat gccaataaag aacggtgcca
     7561 ttaaagacat tatccctaat gttccgttat atacgttgcc gccaatacct ttcagaccat
     7621 taagtgtttc aatggttgag gcgtcgaggc gaatacctaa ggaataaaaa aacgacccct
     7681 ccccaaagct tagaaaaacg ttgttaatta atacaaacat ggcccccgca agggttaacg
     7741 gcattaagcg aataaagcca tttttgattg cattaacgtg tggctgcttt cctattttaa
     7801 ctgcaaaagg gaggagtacc ttttcaagcg atgcaataac attactcata gaaaaatacc
     7861 cttaaaaacc gcaatttaaa tattgcggta ttgatttatg aaataactct ttgacgggaa
     7921 aatttaaaat aaattaattt gctgcggctt ttttaatcgc tgcaaccgca gccttaagca
     7981 cgcctaaacc atcgactttg ccataaagca gcgagtcaat tacttcaacc ggtttgttgg
     8041 gtaacaaacg ctggatttcg ggcaacatat aagcaatctg cggccctaat aacacgacat
     8101 cggcattctg acctttttca ccagccagtg tttccggaaa tgcttcaata atgaccggaa
     8161 cttcatattt ttctgcctgt gcgcgcattt ttgataccag taaagaggta gacatgcccg
     8221 cagaacaaaa cagataaatg tgtttctttt ccataaaact gccctcatcg acgattatct
     8281 gtcagccaga cactccgcaa gccttaacct gcttccatgc tctgggtaac ttgcgaaacc
     8341 aacatgactt tttttgtggc tgaaaggagt atacggtata gacctgagca atagtatttc
     8401 tttgaccttg taaattgtct ctccttgacc tgcggttatg accctcttca catttcgggc
     8461 aaataattcg cgaagataat taagaactca ggccaaaaaa aaccggcgca atggccggtt
     8521 tccgttgtta ctcaagcttt cagacgaagt gattacttcg cagcctgtgg atcagtgtcg
     8581 tattcagcac aggtctgata accggagttg atgacatgtc cggtatcatc taacgcgaca
     8641 aagtaggttt ctgctttacc atcacgttga cccagaatgt aggtctggca agtaccacga
     8701 gcatggatca tgctcacttc agacgaaggt ttacccgcaa tttgtgcaac ctgcgcccgg
     8761 ctcatgcctt ttttgacgtc tttcaccaca ggctgtacaa actggtcttt ggtacgatca
     8821 taagccgtac aacccgccag catggttaat accgccgctg cactcagaat tcctgccata
     8881 ttcttgttca tattccgtcc tcttgtttat cagcgtgtta gataagcctg gaatacattg
     8941 ggcgcttttt caagcccgtg aacgaaacgg ctccgctttc agaggattcc tgtatgacgt
     9001 tttaaccacc attcagcccg ctgtcgcttg tcgtttcagt agcaacgggt tagctttaag
     9061 gaagttttgt cttttctgtc tggaggggtt caatgacatt gcaacaacaa ataataaagg
     9121 cgctgggcgc aaaaccgcag attaatgccg aagaggaaat tcgtcgtagt gtcgattttc
     9181 tgaaaagcta cctgcgaact tatccgttca ttaaatcact ggtgctcggg atcagcggcg
     9241 gtcaggactc cacgcttgcc ggtaagctgt gccagatggc gattaatgag ctgcgccagg
     9301 aaaccggcaa cgaatcactg caatttattg ccgtacgcct gccctatggt gttcaggccg
     9361 acgaacaaga ttgccaggat gccattgcct ttattcaacc ggatcgcgta ttaaccgtta
     9421 atatcaaggg cgcggtattg gctagcgagc aggcattgcg ggaagcaggc attgaactga
     9481 gcgattttgt ccgtggcaat gaaaaagcgc gtgagcggat gaaagcacaa tatagcattg
     9541 cgggtatgac cagcggtgtc gtggtgggca ccgatcatgc agcagaagcc attaccggat
     9601 tcttcactaa atatggtgac ggcggtacgg atattaatcc gctgtatcgt ctcaacaaac
     9661 gccagggtaa acagttgctg acggcattag gttgcccgga acacctttat aagaaagccc
     9721 caacggccga tctggaagat gatcgccctt ctctgccaga tgaagtggca ctcggcgtga
     9781 cctatgacaa tatcgacgac tatctggaag ggaaaaacgt acctgaacag gtcgccagaa
     9841 caatagagaa ctggtatctg aaaaccgaac ataaacgccg tccgccaatt accgttttcg
     9901 atgatttctg gaaaaagtaa taatttgcac ataatggttt gtgcgaaaaa gagtaatttg
     9961 ttcacgccgg atgcggcgtg aacgccttat tcgacctaca aaactatgca aattcaatat
    10021 attgcaggag tcgaataggc ctgacaggcg tagcacgtca gacggtgtaa cctttgtcat
    10081 cgacccgcct cttttttaat cgcttcccgc ctgttacact ggatagataa ccagcattcg
    10141 gagtcaacag tggtacggcg tttaacttct ccgcggctcg aatttgaagc tgcggcaatt
    10201 tatgaatatc ccgaacattt acgttcattc cttaatgact tacccacccg accaggggtg
    10261 tatctgtttc atggcgaaag tgacaccatg ccgctctata tcggcaaaag cattaacatc
    10321 cgcagccgcg tcctttctca tttacgtacc ccggatgaag ccgccatgct acggcaatcc
    10381 cgacgcatca gctggatctg caccgcaggc gaaatcggcg ctctgctcct tgaagcgcga
    10441 ttaatcaaag aacaacagcc gctgtttaat aaacggttgc gccgcaatcg ccagctctgt
    10501 gccctgcaat taaatgaaaa gcgcgtcgat gtggtgtatg ccaaagaggt ggatttttca
    10561 cgagccccca acctgtttgg cctgtttgcc aataggcgcg cagctttgca agcattgcag
    10621 agcatcgctg atgaacaaaa actttgttat ggcctgttgg gactggaacc gttaagtcgc
    10681 ggtcgtgcat gttttcgttc agcgctaaaa cgttgcgccg gagcatgctg cggtaaagag
    10741 agccatgagg aacatgcgct acgcttgcgc cagtctctgg agcgtttgcg ggtggtgtgt
    10801 tggccttggc aaggtgcggt ggcactgaaa gaacagcacc cggaaatgac tcaatatcat
    10861 attattcaaa actggctgtg gctgggggcg gttaattcgc tggaagaagc gacaacgtta
    10921 attcggacac ccgccgggtt tgatcacgac ggttataaaa ttctttgtaa gccgctgctt
    10981 tccggtaact atgaaattac tgaacttgat ccggcgaatg accagcgagc cagttgattt
    11041 cactgaacaa cagtttacct tgcggttgta aaagccgcag ggtgtgcctg ccatcgaacc
    11101 agcacgcgcc ctggtcggta gtgagcaatt tatcgcccag ttgccacgcc ccgttaatca
    11161 caaacaccac cccgccgcgt gagccaaagg tagtaaacgt acgttcggca attctgactt
    11221 tcgccttaca gacatccagg cgtgtcatga tgttgaaatc catcgacatc tgccctgccg
    11281 tcagtttcgc ttttaccacc tggtccgccg caaaggcaaa aggctgtaac ggttttaagg
    11341 tatggttaaa gcggtctgcg ctttcaagga acatctcgcc gccttccagc aacgtcacta
    11401 tcctttccat gccgggaaac aaagaaaact ccccattcgc cgcgatggat gcaatgctgg
    11461 cacgccagta aaaatcacgt tttgccggtg ggaaagtgca aatttcgcgc gtttcaccgg
    11521 cagcgtttcg ccacagattc accgacattt tacgcatatc aaagtattcc atactcgctc
    11581 ccggcccgtt cttttcattg ttatcgttca ggtaaccgtg gatggttatc ggcaactcgg
    11641 gtgatttacg ttagtggtga tcaggctttt tttacaactg tttgagaaga gaaaagaaaa
    11701 ccgccgatcc tgtccaccgc attactgcaa ggtagtggac aagaccggcg gtcttaagtt
    11761 ttttggctga aagattattc agcagttgca ggcattttac cttttgccgc tggacgttct
    11821 gtcagacgct tctcaaaatt agcattaaat tgctttttct gttccggcgt caggatgttg
    11881 taaattttgt tctgggtttc catgtgcgcc agcatgttag ctttgcgctg ttcttccatt
    11941 tttgcgatct gcgcttcagc ttttgcttta tcgaaggtat cgctggcaat gatgtcatgc
    12001 attgcgcggc gttcttccag cggcggacgt ttcatctggt cacgctggcc tttcatgatt
    12061 tcgcggatct gctgtttctg cgcgtcggtc aggttcaggt ctttgaacat catgtcctga
    12121 tgcggaccga acttgccttt gtggtgcatc atcggcttcg cgtcagccgg tgctgcggta
    12181 gtggtgtctg cggcatgggc caggttagcc gcgccaagag ccagggtaga ggcaacaaac
    12241 agtgcagtta atttacgcat attctatatc cttcctttca gttatttatt acggctttct
    12301 taagtagcgt gccgtgttga cgagattaac tttactgact ttagcgtcaa ttaatcagag
    12361 caacggtaaa acaatgaaag tgtaaaaaac acttttgcgc caattatgga gaaaaaaaga
    12421 aaatttgatg gagagtgatg agagaataat acaacacgat gattttgcag agattatgaa
    12481 gaactatacc ggatgactgg tgataaataa agcaaataac caggattaat ctgtattaat
    12541 ttataagaaa gcaacttaat acccgcagaa tgatttctgc gggtaagtat tagcttattt
    12601 tttcgagcat taatcccgcg cgtaatccca acgctaccaa cggattaggg aataacacat
    12661 actctacatc atgggttacg gtaaaacgtt cctctccgtc ctgcgccagc aatgttcctt
    12721 tctcaaacgg cataaaattc agcgtgtcac ttgccatatg catttcgaag gacggcgagt
    12781 ggcgagtaat ttgcgaaacc acccgataac ggagcggcgg tgttctcacg ataccgacac
    12841 tctcaccaga tagcagcgca gcaattgcgc tggcagttac tgcaaactgg cgaagatcgt
    12901 tttgcccaaa gggcaacgct ttgccaagtt ccagcgtaca ggccagcgcg ccaaaatgtc
    12961 tggcgctgaa atgggtaaac gtaccaccag gttcctgatg gaacaccagc gcctccagcc
    13021 ccgccgcacc cagccacgtc agaaatttct cgtcccaggg aatgtcgcgt tgcggtaata
    13081 caccgaactg cggatgcaag gagccacgaa ttgcggtatg tagatcaagg tgccagcgca
    13141 cagattcttt gcccaggtca taaaaatctt ccaggcactg ttccagttcg cgcgcccgac
    13201 aggtttctcc gctttcagca aatagctgcc aacgaccgcc aaacattcga ttcatatcgc
    13261 tatggcaata acgtttccct tgcttcagcg caggaggatt cccgaggatc accagcaacc
    13321 gccaacgtaa cgggatctcg ccgtgagata tcgcgccaag caacgcgtcc agcatctcca
    13381 caggtgccgt ctcattaccg tgtattcccg ctgaaatcac cagtgcgcct tgcggtggcg
    13441 ttaatggcgt cagttccagc acaccatcgc ccagccagcg ccagcgaacg ccgttgattt
    13501 ctcgctcggt gataaccggt tttttacccg ttaaggtcag agcaagaaaa ttatccattg
    13561 ccccctccct cgcgctggaa cggataaacc gaaccgagat tcagtaattg gctcaataca
    13621 tccagtgctt cccgccctcc gcgcagcaat tgcgggtcgg ccagatcggc agcagtaagg
    13681 cgatcgcggt agtaacgatc cacccagtca ttgagcgcat taaacagcgt atcgttcatc
    13741 atcaccgccg gattcaccgc ccggcgttct tcttctgtca ataccacccg caaccgcagg
    13801 cacgccgggc cgccgccatt cgccatgctt tcacgtaaat caaagacttt tagttcgcta
    13861 atcgggttgt cagcggcaag gagttcattg agataacccc atactccggc gtgttcccga
    13921 cactcctgag gcagcaccaa catcatggaa ccatcatcgc ggctcaacag ttggctgtta
    13981 aacagatagg tagacaccgc atccgacacg gaaacctgag ttgccggaac ttctatcgcc
    14041 ataaaaccgt tcacccgcgc acgcaggttt gccagtaact gtgactggcg agcgaacgcc
    14101 tgttggtggc aaaacagcac ctggcggtta ctcacggcaa tcacgtcatt atgaaaaacg
    14161 ccctggtcga taacgtccgg gttttgctgg gcgaaaatca cctgttgggg attcacctga
    14221 ttcagccttg ccaccgcctc gctggcttcg cgagtctgtc gcgccggata acgggaaggc
    14281 cgggtatcat tgccttcttc tcgcccgtag acaaaaagtt gcatacccgg ctcaccgtaa
    14341 tgaccgccga gacgattgtg gtttgccgcc ccctcatcac cgagcaacgc tacctgcggc
    14401 aacgccgaat gaacgctaaa tttctcttcg tcgttaaaaa tcgcttttaa aagtgattcg
    14461 gtgacgtgcg cttccagcga gcggtgaaat ttattgttca ggttggcaac ggtgagatgc
    14521 actttgccat ccagcgtatc ggcagatggc gcgatcgttg ccgcattggc tacccacatt
    14581 ggcgaagcgg aactgacgct ggaaagccag tgcggtgcct ggcgtgcaac tttttccagt
    14641 acctgctcat cgctaccact gaatcccaac tgacgcagca ccggaataaa cggacgctcg
    14701 tgcggcggga tcacggcctg ggggaatccc gcatcggcaa gggctttcat tttcagtaag
    14761 ccctgttttg ccgcctgtcg cgggttagac acctgaaaac ggtgacgggt agaggcttca
    14821 ttaccaaacg acaggccagc gtaatgatgc gtcagcccta ccagcccgtc gaaattaact
    14881 tcccaggcgt tcatcgcacc acctcatcgg aaaaatccag cccggggtta agcgttgcgg
    14941 gcaaagttaa cgagtccgac tccaggctcg ccataggcca tgcgcagtaa tctgcggcat
    15001 accaggcgct ggggcgatgg ttaccggatg caccaatgcc gccgaatggc gcggtactgg
    15061 cagcaccagt aagcggtttg ttccagttaa caatccccgc ccgcgcctcc agcaacagtt
    15121 gatcgaattt ttcccgctcg ggggaaacca gaccgcaaga gagtccgaag cgagtgttat
    15181 tcgccattag aatcgcttcc tcgaaagaat cataacgcca gacgcgcaat aacggtccga
    15241 acacctcttc atctggtacg ccagcaacgc ctgtcatttc aatgatcccc ggcgtcagca
    15301 acgatgtctc tgattgtaat aagcgcggcg caagcagggt tcgtccgccc atcgcttcca
    15361 gttgctgcca ggcagtaacc acctgctgtg cggcctgttc agaaatcagc ccgccaataa
    15421 acggctgcgg ttcgtcatcc cagttgcccg gcgttaatcg ctggctgacg gcaaccagac
    15481 gagcaagaaa cgcatcgccc tgcgctccgc ttttgagcaa taaacggcgg gcgcaggtgc
    15541 agcgttgccc ggctgtgaca aacgccgact gaatggtcag atggacagcc gcgtcgatat
    15601 ccgccacctc atcgataatt agcggattat taccgcccat ctcaagggcg agaattttct
    15661 ccggctgacc ggagagctgg cgatgcagct ggtagccggt attggcgcta ccggtaaaca
    15721 gcaaaccgtc gagatcctcc agcgcactca gcgcctgacc cgtttcacgc ccgccctgca
    15781 ccaggttcag tacgcccggc ggcaagccag cctgctgcca taaacgcatt accgcttcgc
    15841 cactccacgg tgtcagttcg ctgggtttaa agataatggt gttacctgcc agcaatgccg
    15901 gaacgatatg tccgttcggc aaatgaccag ggaaattata cggcccaaac accgccagca
    15961 cgccgtgcgg gcgatgtcgc aggctcgccg caccgtccgg catttcacta cgctgctcgc
    16021 cggtacgaac gtgatacgcc ttaattgata tcgcgatttt attgatcatc gccgtcactt
    16081 cggttgccgc ttcccagcgc ggcttacccg tttctctggc aataatcgcg gttaattcgc
    16141 ctttattcct ttccagcaat ccggcaaagc gttcgacaac gacctgacgt tcagccaatg
    16201 agagccgcgc ccagcgcgga aacgccgcac gggctgcgcg acaagcctgc ccgacctgag
    16261 cggcatcggc atcattgcct tgccataaca cctcgcccga taccggatta cgcttcacac
    16321 gcgatgcgcc ctggcccgtt atccagtcac cgttaatcca taaagtcatg ctgttttctc
    16381 ctctgcgcac aggcgcacca gacgaacgcg atcccctgcg tggcatttga gggcatccag
    16441 ttgtgcggcg gttaaaatca aacgctcggt tgccggatcg gtacgcgcca gcaccacgcg
    16501 gaaatggtga taattttcat tggcgaccag gcaggccgga aaatcgccct gcgcaggctg
    16561 cccttctgcc acttccacca gccgactttt acgaatggcg cgcacgcggt cgatgtcaca
    16621 ctcaagcgtt ggcccgccgt cgaagatgtc gatatagttg cggtaacgaa aaccttcttt
    16681 ctccagcacc gcgcgggcag gcgcggtttg cggatgtacc tgaccgatga cgtcctgggc
    16741 ttcctgggat aaaaagtggg tatagatcgg atgtttcggc atcagttctg caataaatgc
    16801 cttttgcccg gtgccgcaga gaaaatcggc gcggctaaaa tccatcgaaa agaagcgttt
    16861 accgaggctt tgccagaacg gtgaatagcc gtgttcgtca atcaccccgc gcatttcagc
    16921 aaccactttg tcattaaact tgtcgcgaaa agccgccata aacataaagc gcgatttcga
    16981 cagcaaatag ccgttgccct ctttgcgcca gtccgggtcg agaaacagcg tgcacagctc
    17041 gctgctgccg gtgtgatcgt tactgagaaa cagcgtcggc aatgcgttat agacattcag
    17101 ctcttttgag gcgtgaacca acgtgccgac gcgatagttg taccagggat cgttcagccc
    17161 aaccgccacc tcaatggcac aaatccccgc cacggtgcct gtctcgctat cttccagcac
    17221 gaacacatag ccctgctcac ttttgggcag ttcgccttgc caggttttga ttgccctttc
    17281 gatacgcgcc gaaagcgtgg cttcattggc gggaagcgac gtcaggccgc cgcccgtttt
    17341 gctggcaagc tgcatcagcg ccgagacatc tgatcgctca acgggacgga tgaccatcat
    17401 gatgaacctc ggctaacaaa gtgttcgcaa gcagctgcaa agcgatccag tccggtcgtc
    17461 acctcttctt cgctgacatt gagcgcaggc gcaaaacgca ccacgttgcc acccgcaatc
    17521 agtaccatca cgcctgcttt cgccgcttcc tgagagatct gtttcgcttg cccggcgtaa
    17581 tcggcattca gtacacagcc aatcagcaaa cctaagccgc gaacttcact gaacaaacca
    17641 tagcggtgat taatagtatt aagacgctca acaaaccagt cgtgacgctg tttaacgcca
    17701 ttaagcatct ctggtgtgtt gatgagctcc agcactttgc ctgccaccgc cgaggccagc
    17761 ggattaccgc cataggtggt gccatgagtg ccaacggtca tcacgcgggc gcactcttcg
    17821 gttgccaaca acgcaccgac cgggaaaccg ccgcccagcg ctttggcggt agttaacaga
    17881 tcaggcgtca cgccgtagtg catataggca tacagttccc cggtgcgccc gacgccggtt
    17941 tgtacttcat caaaaatcaa cagcgcattg tggcggttac acaattcacg cagaccttgt
    18001 aaaaacgcgt tgctggctgg caccacaccg ccttccccct ggatgggttc gacaatcacc
    18061 gcacaggtag agtcgtcaat cagcgcgctg gcagagttaa tatcgttata tgcagcatga
    18121 cgaatatccg ccggcagtgg cgcaaaatcc tgtgaatagg ctggctgccc acccgcactg
    18181 acagtaaaca gcgtgcgacc atgaaacgca tttttgaacg ccacgatgcc gctcttatgg
    18241 ctgccgtagc ggtcgtgagc gaatttacgc gccagtttta gcgccgcttc gttggcttcc
    18301 gcaccggagt tacaaaagaa gacgcgatcg gcaaacgtgg cgtcgatcaa ttttttcgcc
    18361 agtcgcagta ccggctcgtt ggtgtaaccg ttgccggtat gccagaactt actcgcctgt
    18421 tcgttcagcg cttcacgcag ttccggatgc gcatggccca gcgcgttcac cgcaatgcca
    18481 cccgcgaagt cgatatactc tttcccctgc tgatcccaca agcgcgaacc ttcgccacgt
    18541 accggtataa agggtgccgg agcgtaaaca ggtatcatcc attcatcaaa gttttcacgc
    18601 gtaattggct gagacatagc gacctctaca gtaaataatt cgttatttat atgttaacaa
    18661 taagtaatgt ttgcgctgta aatgtagatt gcagggttcg tgccagccag tgataaaagt
    18721 gcataaacgg cggaggctaa ctggaaatca aggagttata accaaaccat atgcatttaa
    18781 agtgcatata aagtgaatac gtttgcgatg tgggtgaata aaaagaataa aaaacgcaat
    18841 gttatgcaga agtaaaatat aattctggaa ttgtgatcat tgacgaaatt tactggaaat
    18901 tactgcgcca ttctgacgca gcgcgcacca aaagcgggca ttttttgcgc catcgttgac
    18961 atcattaaca accatcgatc aaatcactta acaacaggcg gtaagcaacg cgaaattctg
    19021 ctaccatcca cgcactcttt atctgaataa atggcagcga ctatgaaatt tgtctctttt
    19081 aatatcaacg gcctgcgcgc cagacctcac cagcttgaag ccatcgtcga aaagcaccaa
    19141 ccggatgtga ttggcctgca ggagacaaaa gttcatgacg atatgtttcc gctcgaagag
    19201 gtggcgaagc tcggctacaa cgtgttttat cacgggcaga aaggccatta tggcgtggcg
    19261 ctgctgacca aagagacgcc gattgccgtg cgtcgcggtt ttcccggtga cgacgaagaa
    19321 gcgcagcggc gaattattat ggcggaaatc ccctcgccgc tgggcaatgt caccgtgatc
    19381 aacggttact tcccgcaggg tgaaagccgc gaccatccga taaaattccc ggcaaaggcg
    19441 cagttttatc agaatctgca aaactatctg gaaaccgaac tcaaacgtga taatccggta
    19501 ctgattatgg gcgatatgaa tatcagccct acagatctgg atatcggcat tggcgaagaa
    19561 aaccgtaagc gctggctgcg taccggtaaa tgctctttcc tgccggaaga gcgcgaatgg
    19621 atggacaggc tgatgagctg ggggttggtc gataccttcc gccatgcgaa tccacaaaca
    19681 gcagatcgtt tctcatggtt tgattaccgc tcaaaaggtt ttgacgataa ccgtggtctg
    19741 cgcatcgacc tgctgctcgc cagccaaccg ctggcagaat gttgtgtaga aaccggcatc
    19801 gactatgaaa ttcgcagcat ggaaaaaccg tccgatcacg cccccgtctg ggcgaccttc
    19861 cgccgctaat ttagcagctc tcctggctca aactgggtca ggagaattaa ccttgagaaa
    19921 aatcaacaaa ctgtcagtaa tgatttgttg cctgccgtcc tttgttatac cgtcactgcg
    19981 tttttagttg tctgaccact tctctattat caagtttgat ataggaaact ccacgatgaa
    20041 cgctgagcgt aaatttcttt tggcctgtct tatttttgcg ctggtcattt acgctatcca
    20101 cactttcggt ttattcgatc tgctcaccga tttaccccac ttacagacac tcatccgcca
    20161 gagcggattg ttcggttata gcctctatat tctgttattc attattgcca ctctctttct
    20221 gttaccagga agcatactgg tgatcgctgg aggaatagtt tttggcccgc tcttagggac
    20281 actactctca ttaattgccg ccacgctcgc ctcctcgtgc tcattcctgc tggcgcgctg
    20341 gctgggacgt gatttactgc tgaaatacgt tggtcatagc catacctttc aggccattga
    20401 aaaaggcatt gcgcgtaacg gtattgattt tcttattctg acccgcttaa tcccgttgtt
    20461 tccttacaat attcaaaatt acgcttacgg attaaccaca atcgccttct ggccttatac
    20521 ccttatttcg gcactcacga ccctgcccgg tattgttatt tataccgtga tggcaagcga
    20581 tctcgccaat gaaggcatta cgctgcgctt tattttacaa ctctgtctgg cgggcctggc
    20641 gctgtttatt ctcgtccagc tcgcaaaact ctacgcccga cacaaacatg tggatctgtc
    20701 tgcttcgcgc cgcagcccac ttactcaccc aaaaaatgaa ggatagaacg atgtcgcaac
    20761 attattcagt gtcatggaaa aaaggactgg ctgcactctg cttactggct gttgccgggc
    20821 ttagcggctg cgatcaaaaa gagaatgcgg cggcaaaagt ggaatacgac ggactttcga
    20881 acagccaacc gctgcgcgtc gatgccaata accatacggt aaccatgctg gtgcaaatta
    20941 atggtcgttt cctcaccgac gacactcgtc acggtattgt gtttaaagat ggctccaacg
    21001 gacataaatc gctgtttatg gcttatgcga ccccgaaagc attttatgaa gccctgaaag
    21061 aggcaggtgg tacgccgggc gaaaacatga cgatggataa taaagaaacg actcatgtca
    21121 caggcagcaa actggatatt tcggtcaact ggcaaggggc ggcaaaagcg tattccttcg
    21181 atgaagtgat tgttgacagt aatggcaaga aactggacat gcgctttggc ggtaatttaa
    21241 cggcagcaga agagaagaaa acgggttgcc tggtgtgtct ggatagctgc ccagtcggca
    21301 tcgtcagcaa tgcaacatac acttatggtg cggtggaaaa acgcggcgaa gtgaaattca
    21361 aaggcaatgc ctcagttctc ccggcggata acacgctggc aacggttacc tttaaaatca
    21421 ccgaataaag ccaggataaa ggatgatgaa gatacaatcg cgtaaaatct ggtactaccg
    21481 tataaccctc atcatcctgt tgttcgctat gctgctcgca tgggcgctgc ttcccggcgt
    21541 ccatgagttt atcaatcgca gcgttgcggc gtttgccgcc gtggaccaac agggtataga
    21601 acgctttatt cagtcttacg gcgcactggc ggcagttgtc tcgttcttgt tgatgatttt
    21661 acaggccatt gctgcaccgc tacctgcgtt tttgatcacc tttgccaatg cgtcgctgtt
    21721 tggcgcgttc tggggcggct tgctgtcgtg gaccagttcg atggccggcg cggcgctgtg
    21781 cttttttatc gccagagtga tgggccgcga agtggtggaa aaattaaccg gcaaaaccgt
    21841 gcttgacagt atggacggct ttttcactcg ctacggcaaa cacaccatcc tggtctgtcg
    21901 gttattgcct tttgtccctt tcgatccaat cagctatgct gccggtctga cttcaatacg
    21961 ttttcgctcg ttttttatcg ccaccgggct tggtcaatta ccggcgacta ttgtttattc
    22021 ctgggcgggc agcatgttaa caggcggtac tttctggttt gtcaccggac tgtttattct
    22081 gtttgccctg accgtggtga tttttatggc gaagaaaata tggcttgagc gccagaagag
    22141 gaatgcctga tgggtttacc gccgcttagc aaaattcctt tcattttacg tccgcaggcg
    22201 tggctgcatc gtcgccatta cggcgaggtg ctaagcccga ttcgctggtg ggggcggatc
    22261 ccgtttatct tttatttggt gtcaatgttt gttgggtggc tggagcgcaa acgctcaccg
    22321 ctcgatccgg tagtgcgatc gcttgtcagc gcgcgcattg cgcaaatgtg cctgtgtgag
    22381 ttttgcgtgg atatcaccag tatgaaagtc gccgagcgta ccggcagcac cgataaactg
    22441 ctggcagtgg ctgactggcg gcaaagcccg ctcttcagcg atgaagaacg gctggcgctg
    22501 gagtacgccg aagccgcaag cgtaacgccg ccaacggtcg atgatgccct gcgcacccga
    22561 ctggctgcgc attttgacgc tcaggcgctc accgaactga cggcattgat cggcctgcaa
    22621 aacctgtcgg ctcgttttaa ttctgccatg gacattcccg ctcaggggct gtgccgtatt
    22681 ccggaaaaac gttcttaagg agagaagatg cgccattgtg ggtggttgct gggattgtta
    22741 tcgctgtttt ctctggcaac acatgccagt gactggcagg aaattaaaaa tgaggccaaa
    22801 gggcaaaccg tctggtttaa cgcctggggc ggcgataccg caattaaccg ctatctcgac
    22861 tgggttagcg gcgagatgaa aacccattac gctataaacc tgaagattgt tcgtctggcg
    22921 gatgccgcag acgcggtgaa gcgcattcag accgaagctg ctgccggacg taaaacgggc
    22981 ggctcggtgg atctgctctg ggtgaacggc gaaaacttcc gcaccttaaa agaggccaat
    23041 ttattacaaa cgggctgggc ggagactctg cccaactggc gctatgtcga cacacagctg
    23101 ccggtgcggg aagatttttc agtgcctaca gaaggggctg aatcgccctg gggcggcgca
    23161 caactgacgt ttatcgcccg ccgcgatgtt acgccacagc caccacaaac gccgcaagcc
    23221 ttactggagt ttgctaaagc caatcccggc acggttacct atccgcgccc accggacttt
    23281 accggcacgg cgtttcttga acagttgctg attatgctga cgcccgatcc cgccgcgtta
    23341 aaagttgccc cggataaagc cactttcgcc cgcgtcactg cgcccttgtg gcaatatctt
    23401 gacgcgctac atccctattt atggcgcaaa ggaaaggatt tcccgccttc gcccgcgcgg
    23461 atggatgctc tgctgaaagc cggcacattg cgcctgtcgc tgacctttaa ccctgctcat
    23521 gcccagcaaa aaatcgccag cggcgatttg cctgcaagca gttacagttt tggttttaac
    23581 caggggatga ttggcaacgt gcatttcgtc accattcctg ctaacgcaaa tgccagtgct
    23641 gcggcgaagg tggttgccaa cttcctgctc tcacccaatg cgcaactgcg taaagcggat
    23701 cccgctgtct ggggcgatcc ttctgttctc gatccgcaaa aactgcctga tgggcagcgc
    23761 gaaacattgc aatcaagaat gccgcaagat ctgccgccgg tactggctga accgcacgca
    23821 ggttgggtaa atgcgctgga acaagaatgg ctacaccgtt acggtacgca ttaatctttt
    23881 tgctgtgggc gatggtggcg gtgatttatg caccactgat cccggcagct ctcacgctga
    23941 tatcgcctgc tttgtcgttg acacactggc aggcgttatt tgccgatcca cagttaccgc
    24001 aggcattact ggcaacgctg gtgtcgacaa ccatcgcggc ggtcggggcg ttgttgattg
    24061 ccctgctggt gattgtggcg ctgtggcctt ggccgaaatg gcagcgtatg tgtgcccgtc
    24121 tgccgtggct gctcgccatt ccccatgtgg cttttgccac cagcgccctt ctgctctttg
    24181 ctgagggagg gctgctttat gactatttcc cgtatttcac tccgctaatg gacaaattgg
    24241 gtattgggct gggcctcacc cttgcagtga aagaaagcgc atttctgctg tggatcttag
    24301 cggcagtatt gagcgaaaaa cggctgttgc agcaggtcat tgtgctggat tcgctgggct
    24361 acagccgctg gcaatgcctg aactggctgc tcttgccctc cgtcgcacct gcactggcaa
    24421 tggcgatgtt ggcgattgtt gcctggtcgc tttcggtcgt ggatgtggcg attattcttg
    24481 ggccaggtaa tccaccgacg ctggcagtaa ttagctggca gtggttaact cagggcgacg
    24541 cggatcaaca aacgaaaggc gcactcgcca gtctgctgct gatgctgtta ctcgccgcct
    24601 acgttttgct gagctatctg ctatggcgca gctggcggcg cactattccc cgcgtagatg
    24661 gcattcgcaa gcctgccaca cctttattac caggcactac gctggcgagt tttttaccct
    24721 taaccggtgt gctgtgtgtg gttctgctgg cgatcctcgc ggatcagtcg acgatcaata
    24781 gtgaagcact catcaacagc ctgacaatgg ggctggtggc gacattcatc gctttgctcc
    24841 tgttactgct gtggctggaa tgggggccac agcgtcgcca gttgtggctc tggttgccca
    24901 ttctattgcc cgctctgcca ctggtggcgg gccagtacac gctggcgcta tggctgaacc
    24961 tggatggaag ctggacggcg gtggtctggg ggcatctgct gtgggtaatg ccgtggatgc
    25021 tgtttatcct gcaacccgcc tggcagcgca ttgattcacg gttaattttg attgcgcaaa
    25081 cactgagctg gtcgcgggcc aaaatcttct tttacgtgaa atgtccgctt atgctacgcc
    25141 ctacgctgat tgccttcgcg gtgggatttt cagtcagtat tgcgcagtat atgccgacgc
    25201 tgtggctggg cgcggggcgt tttccgacgc tcaccactga ggcggtggca ttaagcagcg
    25261 gcggcagcaa tggtattttc gccgcccagg ctttatggca actgctatta ccgcttatta
    25321 tttttgccct gaccgcgtta gtcgcaaaat gggtaggtta tgtcagacaa ggactccgct
    25381 aatgctctgc gtgaaaaatg tttcgctacg tttaccagaa agccgcttgc tgacaaacgt
    25441 taactttacg gtggataaag gtgacattgt cacgttaatg gggccgtctg gctgtggaaa
    25501 atccactctg ttttcatgga tgattggtgc actggctgga cagttttctt gtacaggtga
    25561 gctatggctc aatgagcaac ggattgacat gctacccacc gcacagcgtc agattggcat
    25621 tcttttccag gatgcactgt tatttgacca gttcagcgtc gggcaaaatt tactgctggc
    25681 gctaccgtcg acgctcaagg ggactgccag gcgcaatgcc gtgaaagacg cgcttgatcg
    25741 agcgggactg gctgaaactt atcaccagga ccctgcgaca ttatcaggcg gtcagcgagc
    25801 gcgggtggcc ctgctgcgcg cccttctcgc tcagccaaaa gcgttactcc tggatgagcc
    25861 attcagccgt cttgatgtgg ctctgcgcga tagttttcgc cagtgggtgt tcagcgaagt
    25921 tcgcgaactg gcgatcccgg tcgttcaggt aacgcacgat ctccaggatg ttcctgctga
    25981 tagttctgtt ctggatatgg cgcagtggtc agaaaattac aacaaactgc gataacgcaa
    26041 agtttttctc aatgcgtcag ttcagaatgg cgcactcaaa actacaatgt cgggattttc
    26101 gatgaaacgt gtttctcaaa tgaccgcgct ggcaatggct ttagggctgg cttgcgcttc
    26161 ttcgtgggcc gctgaactgg cgaagcctct tacacttgac cagcttcaac aacaaaatgg
    26221 caaagcgata gatactcgcc ccagcgcgtt ttataacggc tggccacaaa ccttaaatgg
    26281 cccttctggt catgaacctg ccgccttaaa cctctctgcc agctggcttg acaaaatgag
    26341 caccgaacag ctcaacgcgt ggatcaagca acataacctg aaagccgatg ccccggtagc
    26401 gctgtacggt aatggcaaag atgtcgacgc cgtcaaaacg cgactgcaaa aagcaggttt
    26461 tacgcatatc tccattctga gtgacgcgct aagcgaacct tcccgtctac aaaaactgcc
    26521 gcactttgag cagctggttt atccgcaatg gcttcacgac ctgcaacaag gtaaagaagt
    26581 tacggcgaaa cctgccggtg actggaaagt cattgaagcg gcctggggcg ctccaaaatt
    26641 ttaccttatc agccatattc ccggcgctga ctacatcgat accaacgaag tggaaagcga
    26701 accactgtgg aacaaagttt ctgatgaaca actaaaagcg atgctggcaa aacacggcat
    26761 tcgccatgac accacggtca ttctgtacgg gcgtgacgta tacgctgcag cgcgtgtggc
    26821 acaaattatg ctctacgctg gcgtgaaaga tgtgcgcctg ctggacggcg gctggcaaac
    26881 ctggtccgac gcgggtctgc ccgttgagcg cggtacgcca ccgaaagtga aagcggaacc
    26941 ggatttcggc gtgaagatcc cggcgcaacc gcagttgatg ctcgatatgg aacaggcccg
    27001 tggactgctg catcgccagg atgcatcgct ggtgagcatt cgttcgtggc cagaatttat
    27061 cggtacgacc agcggttaca gctatattaa accaaaaggt gaaatagccg gagcacgttg
    27121 gggacacgct ggtagcgact cgacgcatat ggaagatttc cataacccgg atggcaccat
    27181 gcgtagcgcc gatgatatta ccgctatgtg gaaagcatgg aatatcaaac cagatcagca
    27241 agtttcattc tactgcggca ccggctggcg cgcgtccgaa acctttatgt acgcacgcgc
    27301 catgggttgg aagaatgttt ccgtgtatga cggcggctgg tacgaatgga gcagcgatcc
    27361 aaaaaatccg gtagcaaccg gtgaacgcgg cccggacagt agcaaataac attgcaatta
    27421 ctgacgctgg tgcgacttca gcgtcagata cccactccac acccgcgtaa aggtcgtcat
    27481 ccagcacaac gcaccgaaga tccacgcaaa ccacgcaaac catgcaggga ataaacatcc
    27541 cagcacaaac agtaagatcg tttctgtgcc ttcggttaac ccgcccagat aataaaacga
    27601 tttatgcgca taaccgggat tatcaatctg atgtttcgcc gccagcgcag caaaagcgag
    27661 aaaactgctg cctgtgccga taaacgcaaa cagcagccag ccgcctgcca gggcgttttg
    27721 ctgcggtgcg gcgaggataa acccaaaagg taccagcgcg taaaaaagaa aatcgagaga
    27781 aatatcaaga aagccgcccg cgtcggtaag ccctctgcgc cgcgccagcg caccgtccag
    27841 accatcaagc agcctgttca acaaaatgac gacaagcgcc gccagatacc agcccagcgc
    27901 cagaaaaggc agtgccagca cgccgatggc aaatcccact aatgttaaac catctggcgt
    27961 aatgcccggt ttatcaagaa cccgcacgca ctgatgcaac aacggtttaa tccggggatg
    28021 aagatggcgg tctagcacag gcactcctta aatataaagc ctttctgatt gagcaacagt
    28081 gcggatatta tggcattttt cgcttatctg cccgtgtgta atttatgaaa atgattgaag
    28141 ttgttgccgc catcattgaa cgtgatggca aaattttact cgcgcaacgc cccgcccaga
    28201 gcgatcaggc gggattatgg gagtttgccg gtggtaaagt cgagccggat gaaagccagc
    28261 ggcaggcgct ggtgcgtgag ttacgcgaag aactgggcat cgaagcaact gtgggtgagt
    28321 atgttaccag ccatcagcga gaagtttcgg gccggattat ccatcttcat gcctggcacg
    28381 tacccgactt ccacgggacg ttacaggcac atgaacatca ggcgctggtc tggtgctcac
    28441 ctgaagaggc gctgcaatat ccgctggccc ctgctgacat tccattatta gaggcgttta
    28501 tggctttacg cgccgccaga ccagcggatt agtgctaagg gttttgtcat cccgctggca
    28561 ttgcagcagt attccctcgg ctttaattac cgcgccttca gaataatttt tatcctgata
    28621 aacgcagcac tgagtacagg gctgcgctga ctgcccgcct gaactgaaca cttctggcgg
    28681 tacgtttacc tccacgtccg gacgataatg cgggttagcc agtgcaatta atggaaatgc
    28741 taatactacg gcgaacaatg ctcgactcac agggaactcc ttaacgttat tgtctctgct
    28801 actgataacg gtagccgggt ggcaaaactt tagcgtctga gttatcgcat ttggttatga
    28861 gattactctc gttattaatt tgctttcctg ggtcattttt ttcttgctta ccgtcacatt
    28921 cttgatggta tagtcgaaaa ctgcaaaagc acatcacata aacaacataa gcacaatcgt
    28981 attaatatat aagggtttta tatctatgga tcagacatat tctctggagt cattcctcaa
    29041 ccatgtccaa aagcgcgacc cgaatcaaac cgagttcgcg caagccgttc gtgaagtaat
    29101 gaccacactc tggccttttc ttgaacaaaa tccaaaatat cgccagatgt cattactgga
    29161 gcgtctggtt gaaccggagc gcgtgatcca gtttcgcgtg gtatgggttg atgatcgcaa
    29221 tcaggtacag gtcaaccgtg catggcgtgt gcagttcagc tcagccatcg gcccgtacaa
    29281 aggcggtatg cgcttccatc cgtcagttaa cctctccatt ctcaaattcc tcggcttcga
    29341 acaaaccttc aaaaatgccc tgactaccct gccgatgggc ggtggtaaag gcggtagcga
    29401 ttttgacccg aaaggtaaaa gcgaaggcga agtgatgcgt ttctgccagg cgctgatgac
    29461 cgagctttat cgtcatctgg gcgcggatac cgacgttccg gcaggtgata tcggcgttgg
    29521 tggtcgtgaa gtcggcttta tggcggggat gatgaaaaag ctctccaaca ataccgcctg
    29581 cgtcttcacc ggtaagggcc tttcatttgg cggtagtctt attcgcccgg aagctaccgg
    29641 ctacggtctg gtttatttca cagaagcaat gttaaaacgc cacggtatgg gttttgaagg
    29701 gatgcgcgtt tccgtttctg gctccggcaa cgtcgcccag tacgctatcg aaaaagcgat
    29761 ggaatttggt gctcgtgtga tcactgcgtc agactccagc ggcactgtag ttgatgaaag
    29821 cggattcacg aaagagaaac tggcacgtct tatcgaaatc aaagccagcc gcgatggtcg
    29881 agtggcagat tacgccaaag aatttggtct ggtctatctc gaaggccaac agccgtggtc
    29941 tgtaccggtt gatatcgccc tgccttgcgc cacccagaac gaactggatg ttgacgccgc
    30001 gcatcagctt atcgccaatg gcgttaaagc cgtcgccgaa ggggcaaata tgccgaccac
    30061 catcgaagcg actgaactgt tccagcaggc aggcgtactg tttgcaccgg gtaaagcggc
    30121 taatgctggc ggtgtagcaa cgtcaggcct tgaaatggcg caaaacgctg cgcgcctggg
    30181 ctggaaagcc gagaaagttg acgcacgttt gcatcacatc atgctggata tccaccatgc
    30241 ctgtgttgag catggtggtg aaggtgagca aaccaactac gtgcagggcg cgaacattgc
    30301 cggttttgtg aaggttgccg atgcgatgct ggcgcagggt gtgatttaag ttgtaaatgc
    30361 ctgatggcgc tacgcttatc aggcctacaa atgggcacaa ttcattgcag ttacgctcta
    30421 atgcaggccg ggcaagcgca gcgcccccgg caaaatttca ggcgtttatg agtatttaac
    30481 ggatgatgct ccccagggaa catttcttat gggccaacgg catttcttac tgtagtgctc
    30541 ccaaaactgc ttgtcgtaac gataacacgc ttcaagttca gcatccgtta actttctgcg
    30601 atagcagcag atatgccagt aaagaaatcc cattagacta tttttttgat aatcttcttc
    30661 gctttcgaac aactcgtgcg cctttcgaga agcaagcatt atataatgcc aggccagttc
    30721 ttcttcaatt gtcccgtttt gaaaagctgt gcttgatatc gagatcatct atgataattc
    30781 cgccgcccat attagcttcg ccgaggattt accggagcga ttattagcgc aatcagagat
    30841 atagtctgag ggaaaaacag caaatttatt caacaaggcg ataacctgct ctggggcttc
    30901 ctccatgttt gctttaaagg tattggctcc atggtcgcca gaaagaaaat gctccattaa
    30961 ggcacaataa ctttcgctat cttcgatacc ccattgatcc tctaaagact cgcgtctttt
    31021 acttatgata tcgatcgagt caaaaggaag cacatgatat tggaaggtat ctttgccagg
    31081 ttcaggcttt cgcggccaga actccagcgt ttcagaccat tgcttatgat agaatcgata
    31141 aggtgcgatc aattgtagcg cctgtaactt ctcgatactg agcggctcaa tacctttagc
    31201 ctgataataa tgcagttgtt ctttttttgc tttaaaaccg gcccgaacaa taagccccat
    31261 cataattaat agataaagaa aagagcatcc cgcggtaatc aggcctcttt cattcaaacc
    31321 gttggatgtt atcgctgcga acacaaacat tacagcgaca acacatgtta aataaaaccc
    31381 ccacttacaa agcagcatgg ccttattttc tttaatcatc cgttcaaaat tactattaaa
    31441 tatttcccag ccattaaaag aatacttctc gctcccagga tggttttgta ataaaacttt
    31501 tttcatcaca ttccctgtta ttacatactt tagaggcgat aattttatcc atgcaaaaaa
    31561 aatatccaac gaattttctt gatccgctgg atatttcaga atatgactcg aatagcacga
    31621 aagattcact cgcttacgct atcgccccgc ttccgacttc atctgctggc ggactttttt
    31681 tcgcactacg tttacgcggt gcagcctttt tcttatcagc actgccacca ctgcccggag
    31741 ccacaatgcc gcgaaactgc cgcaccggcg tacgtttggc ttgatcaata agctgatata
    31801 gcgtccccac cagcggctgc ataaagtcct gatagcgaca ctgcttttcg ctgatttgcg
    31861 tcagcaccga ttcccagtgc gcggtcatgt ccggtcgcgt cgccatttct ggcagcgaat
    31921 ggaataacgc ttttccggcg tcggtagagt ggatatagcg cccttttttg gtcagaaaac
    31981 cacgcttgaa cagcagttca ataatcccgg cacgggttgc ttctgtcccc agaccatcgg
    32041 tcgcacgaag gatctttttc agatctttgt cctgcacaaa gcgcgcgatc ccggtcatcg
    32101 ccgaaagcag tgttgcatcg gtaaaatggc gcggcggctg ggtttgccgc tctaccactt
    32161 cacctttttc acacagcaac tcatcgcctt tcgccaccac aggcaatggc gtaccgtcgt
    32221 tttcttcatc gcgctctttg ctgcctaaca gcgtgcgcca gcctgcttca gcaagaaaac
    32281 gggctttagc gacaaatttg cctttggcaa tgtccagttc gataacacac ttgcggaaca
    32341 ccgcatccgg gcagaactgc atcaggtatt gacgggcaat caggttatag accttcgctt
    32401 cgttctccgt caggttgatc gcagaactcc gtgcggtcgg gatgatggcg tggtgcgcat
    32461 cgaccttttt gtcatcccaa cagcggttgc gtatatctgg atctaccact ggctgcggca
    32521 acagatctgg tgcatgaacg ctgatggcat tcatcaccgc gtggcgtccg gcaaaatgtt
    32581 cttctggcaa atagcgacaa tcggaacgcg gataagtgat tagcttgtgc gtttcgtaca
    32641 gcttctggca gatatcaagc acgttctgcg cgctcagacc aaagcgtttt gccgcttcaa
    32701 tctgcaacgc cgaaagcgaa aacggcagcg gcgcggattc tgattcccgt ttatcgttat
    32761 agctggtgac aatagccggt tgaccgctga tgcggttaac cacatgctcc gccagtggac
    32821 gatgtaacaa gcgcccttct tcatcctggt acggttcaca cgcttcgctc ggttgccaga
    32881 tagcggtaaa ccgctcatcg gcaggtgtca cgatatgtgc tttgacttca aagaagtctt
    32941 tcgccacgaa gttttcaatc tcttcatcgc ggcgcaccac cagcccaagc acgggcgtct
    33001 gcacgcgtcc gacggaaagc acgccctgat aaccggcatt gcgaccgaga atggtgtaag
    33061 cacgggtcat attgatgccg tacagccagt cggcacgcgc tcgcgccagc gcagaaacgc
    33121 acagcggtac aaactcactg ttggaacgaa gacggtcgat cgcccgctca accgcctgcg
    33181 ggttcaggtc gtttatcaag caacgctgca cctgctggcg cttttccggt gccagttgca
    33241 gatagtccag cacttcatcc accagcaatt gcccttcacg atccgggtcc ccggcgtgaa
    33301 cgatttcgct ggcttcatgc aggaagcgtt tgatgacgtt aagttgtttg gtcacggagg
    33361 gtcgtggctg taattgccac ttttccggga caatcggcaa atccgcaaga ttccagcgcg
    33421 catagcggct gtcgtaggcg tctggctgcg cctgctcaag caggtgaccg atacaccagg
    33481 tcaccacctg accattaccg cactcgataa agccatcgcc tttacggtgc ggtttgggca
    33541 ggacatcagc aatggcgcgc gccagactcg gtttttcggc aataaacaac cgcattgaat
    33601 taacggatct caaccatggc acgaccgccg cgcgctggca ccagttcgcc aatcgccgtc
    33661 agttcaatgc caaactcggc ggctgtagtt ttaacctcat tttctgcttc cggcatgacc
    33721 gccagcagca aaccgccaga agtttgcgga tcgcacagca gatcgcgcac ttcacgcggc
    33781 atttcaccca tcagatgacc gtagctggca aagttacgtt cggtgccgcc aggcactgcg
    33841 cccaacttaa tgtactcttc aacccccggc aattttggga tcgcgtcata gtcaacgcgc
    33901 gcctgcacac ctgcgccctg acacatttcg ctcaaatggc ccagcagacc aaaaccagta
    33961 acgtcggtca tcgcttttac gccttcgatg ttggcaaagg acgcacctgc gatgttcatc
    34021 cggcacatca cttccgtcgc cagtccctga tgttctggtt tcaacagtga ttttttctca
    34081 gccgtggtaa gaacgccgat ccccagcggt ttcgtcagga acagtttgca tccggcttgt
    34141 gcggtactgt ttttcttcac ccgctcggtc ggtacgatcc ccgttaccgc cagaccaaaa
    34201 atcggctccg gcgcatcgat ggagtgaccg ccagccagcg caatacccgc ctgacggcat
    34261 gcatagcgtc caccttcggt tacttcgcgg gcaatttctg gggaaagttt gttaatcggc
    34321 cagccgagga tcgcaatcgc cataatcggt ttgcccccca tcgcgaagat atcgctgatg
    34381 gcgttagtcg ccgcaatgcg gccaaaatcg aaaggattat caacgatcgg cataaagaag
    34441 tcggtggtac tgataacgct ggtgccattg cccagatcgt acaccgccgc atcgtcgcgg
    34501 gtctcattac ccacaagcaa attcggatca acaaacttcg cctgctcact gtgcaggatg
    34561 gtttccaaca cttttgggga aattttacag ccgcaaccag ctccgtggct gtattgggtc
    34621 aaacgaatcg agttctcgct catagacatc tcctgtcaat gcaatccggg tatggtaacc
    34681 ctcattccgt gaagtgataa gtgagagtgt ctgaattcct gcgcctttgc tcacaatcca
    34741 gacagtttcg cgacaattat cagaaataag ttacaaacgg agtcgggtcc gggacgttaa
    34801 tcgacgtaga tgctttcaac tgcggcgtgc cgaggtagag aaaaccgaca attttatcct
    34861 gctcacggca accgaatgct tcacgcacta ccggactttc agttaatgcg ccactgcgcc
    34921 agatgccgcc aaatccttgg gcaacggctg ccatttgcat cgccatgacc gcgcatccgg
    34981 cagacatttc ctgttcccat cgcgggactt tatgattttc ttcgcatttc gccaccaccg
    35041 tgatgatgag cggtgcgcgg aacggcgcat tacgggcttt gtcgatagct ttgtcatcac
    35101 taccggcagc aatcgccccc tgttccagta cggcgctgaa acgctcgcgc ccttcccctt
    35161 caatcacaaa aaaatgccac ggttgcatgg acttatggtc cggcgcacgc atacccgcac
    35221 gcaggatgtt ttgcagttgt tcacccgttg gcgcgggttc agccaggcgg gaggcgctac
    35281 ggcgattgat caatagttcg agtgcatcca tttgattaac tcctgtcgtg atatttattc
    35341 acaaaattaa cacgagagtg gattttgtta cagcacagtc cgcaattcct gctgacaagt
    35401 gccggttggg tcattacgat aaccacatct attgcgcctg tgacaggtgt gaccttaagt
    35461 tgggagaata catgcgaacc ctttggcgat ttattgccgg attttttaaa tggacgtggc
    35521 gtctgctgaa tttcgtccgt gaaatggtac ttaacctgtt ctttattttc ctcgtactgg
    35581 ttggtgtggg gatctggatg caggtcagtg gtggtgattc gaaagaaacg gccagtcgtg
    35641 gcgcactgct gctggacatt tctggtgtga tcgtcgataa acccgacagt tctcagcggt
    35701 ttagtaaatt aagccgccag ctgcttggtg ccagttccga tcgtctgcag gaaaactcac
    35761 tgtttgatat cgtcaacacc attcgccagg cgaaggacga ccgcaatatc accggtatcg
    35821 tgatggatct gaaaaacttc gcaggcggcg accagccgtc tatgcagtac atcggcaaag
    35881 ccctgaaaga gtttcgtgac agcgggaaac cggtttatgc cgttggcgag aactacagcc
    35941 aggggcaata ttatctcgcc agtttcgcca ataaaatttg gctgtcaccg caaggcgtgg
    36001 ttgatctgca cggttttgct accaacggtc tgtactacaa atcgttgctg gataagctga
    36061 aagtttccac ccatgtgttc cgcgtgggta cgtataaatc tgccgttgaa ccgtttattc
    36121 gtgatgatat gtcaccggca gcgcgcgaag ctgacagccg ctggattggt gagctgtggc
    36181 aaaactatct gaatactgtt gccgctaacc ggctgatccc tgctcagcag gtattccctg
    36241 gcgcgcaagg gttgcttgtg ggtttaacca aaaccggtgg cgataccgcg aaatatgcac
    36301 tggaaaacaa gctggtcgat gcactggcat cgagtgccga aatcgaaaaa gctctgacca
    36361 aagagttcgg ctggagtaag actgataaaa attatcgcgc catcagttat tacgattacg
    36421 cattgaaaac gccggcagat accggtgaca gcatcggtgt cgtcttcgct aatggcgcaa
    36481 ttatggatgg cgaggaaact caggggaatg ttggcggtga taccactgcg gcacaaatcc
    36541 gcgacgctcg ccttgacccg aaagtgaaag cgattgtcct gcgtgttaat agcccaggcg
    36601 gcagcgttac cgcgtctgaa gtgattcgcg ctgaactggc agcagcccgg gcagcgggta
    36661 agcctgtggt tgtatcgatg ggcggcatgg cggcatctgg tggttactgg atttccacgc
    36721 cagctaatta cattgtggct aaccccagca ccctgaccgg ttctatcggt atcttcggcg
    36781 tgatcaccac cgtagaaaat agtctggatt cgattggtgt tcatactgat ggtgtctcaa
    36841 cttcaccgct ggcggatgtt tctatcacca gggcactgcc gccggaagcg cagcagatga
    36901 tgcaattaag cattgagaat ggctataaac gctttatcac gctggttgct gatgcgcgtc
    36961 attcgacgcc ggagcaaatt gataaaatcg cccagggcca cgtctggacc ggtcaggatg
    37021 caaaagctaa cgggctggtc gatagtctcg gggatttcga tgatgcggtt gccaaagcag
    37081 cagagctggc aaaagtgaaa cagtggcatc tggaatacta cgttgatgaa ccgaccttct
    37141 tcgacaaagt gatggacaac atgtctggtt ctgtccgggc aatgttgcca gatgcgttcc
    37201 aggccatgtt acctgcaccg cttgcctcgg tagcctctac cgttaaaagt gaaagcgaca
    37261 agctggccgc gtttaacgac ccacaaaacc gttatgcgtt ttgcctgacc tgcgccaacg
    37321 tgcgttaagt cttgtactga gtggccgaca gatcgtcggc cacattattt tttacctcga
    37381 cgaatcctct tcccgctgtc tcgacccata tttccttatc cgcatagtat caggtgcgct
    37441 cctcctgcct cacgtatata cttttgctct ttcgatatca ttcatatcaa tatcatgcaa
    37501 aagaaatcaa tttacgtcgc ctacacgggc gggaccatcg ggatgcagcg ttccgagcag
    37561 ggttatattc cggtgtcagg tcatctacaa cgccaactgg cgctgatgcc ggaattccat
    37621 cgcccggaga tgccagattt caccattcat gaatatacgc cgttgatgga ttcttctgat
    37681 atgacgccgg aagactggca gcatattgct gaagatatta aagcgcacta tgacgactat
    37741 gatggttttg tcattctaca cggtaccgac acgatggcgt ataccgcctc tgcgctgtcg
    37801 ttcatgctcg agaatctcgg taaaccggtc attgtgacag ggtcacaaat cccgctggct
    37861 gagttacgct ctgacggaca aattaatctg ctgaatgcgt tgtacgttgc ggcgaattat
    37921 ccgatcaacg aagtaacgct ctttttcaat aaccgattgt atcgcggcaa ccgcactacc
    37981 aaagcccatg ccgatggttt tgatgcgttt gcctctccaa accttcctcc gttactggaa
    38041 gctggtatcc atattcgtcg tttgaatacg ccacccgccc cgcacggtga aggggaatta
    38101 atcgttcatc caatcacgcc acaaccaatt ggcgtagtga cgatttatcc ggggatttct
    38161 gctgatgtcg tgcgcaattt tctgcgccaa ccggtgaaag cattgattct gcgctcctat
    38221 ggcgtgggta atgcgccaca aaacaaagcc ttcctgcagg aattacaaga agccagcgat
    38281 cgcggtattg tggtggttaa cctgacacaa tgtatgtccg gtaaagtgaa catgggtggt
    38341 tatgccaccg gtaacgccct cgcccatgcc ggcgtaattg gcggtgcaga tatgactgta
    38401 gaagctacgc taaccaaact gcattacctg ctgagccagg aactggatac tgaaaccatt
    38461 cgcaaggcca tgagccaaaa cctgcgcggc gaactgacgc cggatgatta aggagactgc
    38521 aatgccccct cgcgccctgt tactggtcga tttacaaaat gatttctgtg ctggtggcgc
    38581 gctcgccgtg ccggaaggtg acagtacggt ggatgtcgct aaccgcctta ttgactggtg
    38641 ccagtcgcgc ggtgaagcgg ttatcgccag tcaggactgg cacccggcga atcacggcag
    38701 ttttgccagt cagcactgtg tagagcctta tatgccaggt caactcgacg gtttgccaca
    38761 aaccttctgg ccagatcact gtgtgcagaa cagtgaaggc gcacaattac atccgttact
    38821 gaaccaaaaa gcgatcgcag cggtgttcca taaaggcgaa aatcctttag ttgacagtta
    38881 cagtgccttt tttgataacg gccgtcggca gaaaacctct ctcgatgact ggttacgcga
    38941 tcatgaaatc gatgaattga tcgttatggg cctggctact gactattgcg tgaagtttac
    39001 cgtgctggac gcgttacagt taggttataa agtaaacgtg attaccgatg gttgtcgtgg
    39061 cgtgaatatc cagccccagg acagtgcgca cgcgtttatg gagatgtcag cagctggggc
    39121 aacgctatat acgctggcag actgggaaga gacgcagggg taatattagt tgaattcatc
    39181 tctggcctac atttcctcaa tgacattgta ggccagataa tacttgtcag tgttgcattt
    39241 aacctacttg cagctaaaac acgacgtcct aacaagtata tttgccctcc cttaataaca
    39301 ggcttaaata ctagataact cattcactta aacatagcaa taggctttgc tgagatacca
    39361 aaatcttctt ttaactgctg tttgctcttc atgaccatct gaccatttgt gtcaattgtc
    39421 atatgctgtg cttcggtatt atggcgggct tgccacagca tcaccagttg caggcaattc
    39481 tctttttgtt cctcggtcaa cgcaacgcca tcaggccatt tccccagttc aacggcggtc
    39541 gacaaacgct ggtatacctc aggcgtcatg ctgttgataa tgtcatcaag attcataatt
    39601 tttccgctcc tgtggaataa gttgctgaat cgttttttca accgttgatt tcttcgccgt
    39661 tttcgccatc ggtaaagcgt aaagaagcag agttaacaca ataacgttcg cctgttggtt
    39721 gcggcccgtc gggaaagaca tgccccagat gggcatcaca gttaccgcaa cgaatttcta
    39781 tgcgctgcat tccatgtgac aagtctttga tataacgaat ggattcttca ctcaccggtt
    39841 cgtagaaact gggccagcca cagccggaat catacttggt ttcggaatga aacagcgggg
    39901 catcgcagat caaacagtga tatacgccgt cacgcttgtt atgcagtaaa cgacccgtaa
    39961 atggcggttc tgtcccatga ttctgcgtca cgtaaaactg catctcggac aaattttttt
    40021 tcagttcttc tgccgaaggt ttattagcca tttgctcaca tctcacttta atcgtgctca
    40081 cattacgtga ctgattctaa caaaacatta acaccaactg gcaaaatttt gtcctaaact
    40141 tgatctcgac gaaatggctg cacctaaatc gtgatgaaaa tcacattttt atcgtaattg
    40201 ccctttaaaa ttcggggcgc cgaccccatg tggtctcaag cccaaaggaa gagtgaggcg
    40261 agtcagtcgc gtaatgctta ggcacaggat tgatttgtcg caatgattga cacgattccg
    40321 cttgacgctg cgtaaggttt ttgtaatttt acaggcaacc ttttattcac taacaaatag
    40381 ctggtggaat atatgactat caaagtaggt atcaacggtt ttggccgtat cggtcgcatt
    40441 gttttccgtg ctgctcagaa acgttctgac atcgagatcg ttgcaatcaa cgacctgtta
    40501 gacgctgatt acatggcata catgctgaaa tatgactcca ctcacggccg tttcgacggt
    40561 accgttgaag tgaaagacgg tcatctgatc gttaacggta aaaaaatccg tgttaccgct
    40621 gaacgtgatc cggctaacct gaaatgggac gaagttggtg ttgacgttgt cgctgaagca
    40681 actggtctgt tcctgactga cgaaactgct cgtaaacaca tcaccgctgg tgcgaagaaa
    40741 gtggttatga ctggtccgtc taaagacaac actccgatgt tcgttaaagg cgctaacttc
    40801 gacaaatatg ctggccagga catcgtttcc aacgcttcct gcaccaccaa ctgcctggct
    40861 ccgctggcta aagttatcaa cgataacttc ggcatcatcg aaggtctgat gaccaccgtt
    40921 cacgctacta ccgctactca gaaaaccgtt gatggcccgt ctcacaaaga ctggcgcggc
    40981 ggccgcggcg cttcccagaa catcatcccg tcctctaccg gtgctgctaa agctgtaggt
    41041 aaagtactgc cagaactgaa tggcaaactg actggtatgg cgttccgcgt tccgaccccg
    41101 aacgtatccg tagttgacct gaccgttcgt ctggaaaaag ctgcaactta cgagcagatc
    41161 aaagctgccg ttaaagctgc tgctgaaggc gaaatgaaag gcgttctggg ctacaccgaa
    41221 gatgacgtag tatctaccga tttcaacggc gaagtttgca cttccgtgtt cgatgctaaa
    41281 gctggtatcg ctctgaacga caacttcgtg aaactggtat cctggtacga caacgaaacc
    41341 ggttactcca acaaagttct ggacctgatc gctcacatct ccaaataagt tgagatgaca
    41401 ctgtgatcta aaaagagcga cttcggtcgc tctttttttt acctgataaa atgaagttaa
    41461 aggactgcgt catgattaag aaaatttttg cccttccggt catcgaacaa atctcccctg
    41521 tcctctcccg tcgtaaactg gatgaactgg acctcattgt ggtcgatcat ccccaggtaa
    41581 aagcctcttt tgcattacag ggcgcacacc ttctctcgtg gaaacctgcg ggtgaagaag
    41641 aagttctgtg gttgagcaac aacacaccgt tcaaaaatgg cgtcgctatt cgcggtggcg
    41701 taccggtttg ctggccgtgg tttggtccgg cggcacaaca aggtctgcct gcgcacggtt
    41761 ttgcccgcaa cctgccgtgg acgctgaaat cacatcgtga agatgctgat ggcgtagcgc
    41821 tgacttttga attgacgcaa agcgaagaga cgaaaaaatt ctggccgcac gactttacgc
    41881 tgttagcgca tttccgcgtg ggtaaaacct gtgaaatcga tcttgaatca catggcgaat
    41941 ttgaaaccac ctctgccctg catacctact ttaacgtggg tgatatcgct aaggtaagcg
    42001 tcagtgggct gggcgatcgc ttcattgata aagtaaatga cgcgaaagaa gatgtactga
    42061 ccgacggtat tcagaccttc cctgaccgta ccgatcgcgt gtatctgaat ccgcaagatt
    42121 gcagcgtgat taatgatgaa gcgctgaatc gtattatcgc cgtaggccac cagcatcatc
    42181 tgaacgttgt cggctggaac ccgggaccgg cgctttcagt tagcatgggc gacatgccgg
    42241 atgatggcta caaaacattt gtttgtgtag aaacggctta cgcttcagaa acgcaaaaag
    42301 tgaccaaaga gaaacctgca catctggcgc aatccattcg cgttgcgaaa cgttaatttg
    42361 cgttaatgtt gtgtgccggg tgcgatgcat ccggcacgta tcaacatcac accatatcca
    42421 gcgcagtttt tccttttggt gccggatacg ctttatccag catggttaat tccgctgacg
    42481 aaagttcgac ctcaagcaca gccgcattct gttggacatg ggcaatcgtg gccgcttttg
    42541 gaatcgccat cacaccctga tggctgatta cccacgccaa caatacttgt gccgcgctga
    42601 tattgtgagc atgtgcaatt tcgttgacta ccgcgttttt taacagtcca ttgcgcaacc
    42661 gcccggcctg ggctaatgga ctgtaagcca tcaccggcat ctgctgttgc tggcaccagg
    42721 ggagtagatc gtactcaatc cctcgtgaac cgagatggta aagcacctga ttagtggcac
    42781 actgatttcc ccccggcagc tgccagagtt cctgcatatc agcatgatca aggttagaaa
    42841 cgccccagcg gcggattttt ccctgggcga tcaatttttc catcgctgcc acagtctctt
    42901 caaaagcgaa actgccagac cagtgtaata agtagagatc gagataatca gtattgagac
    42961 ggcgtaaact ggcttcgcat gcatttatcg ctttttgccc gccagcattc cacggataga
    43021 ctttagagac gagaaagacg ttatcgcgca gaccggttaa tgcttcccca accacctttt
    43081 cggcaccgcc atcggcatac atttcggcgg tatcaatgag ggttaaaccg agctcaatgc
    43141 ccgcgcgtag tgcagcaact tctgttttgc gctgactggc atcttcgccc atataccatg
    43201 ttccctgccc tatggctggc agtgagacat cgccactaaa ttgaatcatt ttttgttgca
    43261 ttgtttcctc ccaggtattg caccaccgta atgcaaaaca gggcgtgacg ccctgttttt
    43321 atgcacaaaa tgccctggaa agatgcatta tcagaatttg taggtgatcc cggtagaaat
    43381 caggccagtc caggatttat ccaccatcgg gctgtcagta acttcatcag acagacgggt
    43441 atagcgcgcg gtaccgtaaa cactccagtc gccgaggaag ttgtagctgg cgctcagctc
    43501 caggtaaggg ctccagctgt cgttcgggtt atagccacgc agaccgctgc gagcggactc
    43561 tttgcgcgat acgccataat agtattcgtt ctggttttcg ctgttccact gcacaccgat
    43621 acccggggtc acggtcaggc cgccgttggt gtaacgatac aaccaggcca tatcccagac
    43681 gatgccgttg ctgttatcca gggtatcgcc agccagggtg gtacgcaggt aaccgtactg
    43741 ggtaaagtga gcataagaca gaccagccat catggtgctc ttacggtcat ccaggtgacg
    43801 catttggtga ttgccactgt ctttcgcttt gaagtaaagc ggcgaccaat aagcggtaat
    43861 tgaaagtttg tccgttgcgt cattccacag gtagtaacca ccacctaagc cacggaacca
    43921 gaagttatcg ccttcatagt tgattaccgg tactgggtaa acatcggtat cgtaatcttt
    43981 atatgggtgc tcaacgacac ctacgcctgc gcccagggaa aatttacctt cagcgtgcgc
    44041 tacgcctgca gacgttgcga taagcactcc aagtgccaga agtttgagtt tggtcacaat
    44101 taatcattcc ttaaacaaat gtttagcggg cgacaaagtt tacccgtcaa tacatcgaaa
    44161 cccaaccttt ttacgttttc attttttaaa gtaactgttt aattttcctg acgcggatga
    44221 caccgcgctt acagccaaat gaatttagcg ttactggcta ccctggtctt tacattaatt
    44281 atgcaaaatt tatggatgag ttgttgatat gccattgaaa ttaagaaagc cgtgcaggca
    44341 agttttccat ttgccatcta cgcttaattt tgaaggtgta tcaccgggca cgttgttctc
    44401 atcgtcgata aaatggcatg agagttgctg tgttttagca agagacgtcg ttcagtttac
    44461 ctcttccggg agcctctact attcatatga acggctctta acctgtgcta aaaaacgaaa
    44521 ggacggcata ccatgaatat attcgatcac tatcgccagc gatatgaagc tgccaaggac
    44581 gaagagttca cactgcagga gtttcttacc acttgtcggc aagatcgcag tgcttatgcc
    44641 aacgcggctg agcggctatt gatggctatc ggtgagcctg tcatggtcga tacagcccag
    44701 gaacccagac tttctcgact cttttctaac cgggtcattg cacgttatcc ggcatttgaa
    44761 gagttttacg gcatggaaga cgcgattgaa cagattgtct cttatctgaa acacgcggct
    44821 caggggctgg aagagaagaa acaaatcctg tatctgctgg ggcctgtggg tgggggtaaa
    44881 tcatcgcttg ctgagcgact gaaatcatta atgcagctcg taccgattta tgtattgagc
    44941 gccaacggtg agcgtagccc ggtcaacgat catccgttct gtcttttcaa tccgcaggaa
    45001 gatgctcaga ttctggaaaa agagtatggc attcctcgcc gttatctcgg caccatcatg
    45061 tcgccatggg cggcaaaacg cctgcatgaa tttggtggcg atatcactaa gttccgggta
    45121 gtgaaggtct ggccgtcaat tctgcaacaa attgctatcg ccaaaacgga acccggtgat
    45181 gagaacaacc aggacatctc cgcgctggtt gggaaagtcg atattcgtaa actcgaacac
    45241 tacgcgcaga atgacccgga cgcctacggc tattccggtg cgctgtgccg cgccaaccaa
    45301 gggatcatgg aatttgtcga gatgtttaaa gcaccgataa aagtgctgca tccgctgtta
    45361 accgccactc aggaaggtaa ctacaacggg acggaaggta tctccgccct gccgttcaac
    45421 gggattattc tcgcccactc gaacgaatcc gaatgggtca ctttccgtaa taacaaaaac
    45481 aacgaagcct tcctcgaccg tgtttacatc gtgaaggtgc cgtattgctt acgcatttcc
    45541 gaagagatca aaatctacga gaaattgctt aatcacagtg aattgactca cgccccctgc
    45601 gcccctggca cgctggaaac gctgtcacgt ttttccattc tttcgcgcct taaagagcca
    45661 gaaaactcca gcatttattc aaagatgcgg gtttatgatg gcgaaagtct gaaagacacc
    45721 gatcccaaag ccaagtcgta tcaggaatat cgtgactacg ccggtgtcga tgaagggatg
    45781 aacggtctgt cgacgcgttt tgcgtttaag atcctctccc gcgtgttcaa cttcgatcat
    45841 gtagaagtgg cggcaaaccc ggtccatctg ttctacgtcc tggaacagca gatcgagcgc
    45901 gagcagttcc cacaagagca ggcagaacgc tatctggagt tcctgaaagg ttatctgatc
    45961 ccgaaatatg ccgagtttat cggcaaagag atccagacgg cctaccttga atcctattcc
    46021 gaatatgggc aaaacatttt cgaccgttat gttacctacg cggatttctg gattcaggat
    46081 caggagtatc gcgatccgga taccgggcag ctgtttgacc gcgagtctct taacgccgag
    46141 ctggagaaaa tcgagaaacc ggcggggatc agtaatccaa aagatttccg caacgagatt
    46201 gttaacttcg tactgcgcgc cagagcgaat aacagcggac gcaatccgaa ctggaccagc
    46261 tatgaaaaac tgcgcacggt tatcgagaag aaaatgttct ccaataccga ggagctgttg
    46321 ccggttatct cgtttaacgc caaaacgtca accgacgagc agaagaaaca cgacgacttt
    46381 gtcgaccgta tgatggaaaa aggctacacc cgtaaacagg tgcgtttact gtgcgaatgg
    46441 tatttgcgcg tacgtaaatc gtcttaacaa ccctggcccg gtacacatgt taccgggcct
    46501 acaacgacag cgaaccgtgg gcctgagaag cggcaacaca ggcgtagcat acagttggca
    46561 aatgtagtac ggggggcata tgacctggtt tattgaccgg cgtctgaacg gcaaaaacaa
    46621 aagcatggtg aatcgccagc gttttttacg ccgttataaa gcgcaaatta aacagtcgat
    46681 ctccgaggcc attaataagc gttcggtgac tgacgtcgac agcggcgaat ccgtatccat
    46741 tcccacggaa gatattagcg aaccgatgtt tcatcagggg cgtggcggtc tgcgccaccg
    46801 cgtgcatccg ggcaatgacc atttcgtcca gaacgaccga attgaacgtc cccagggtgg
    46861 cggcggaggt tccggcagtg gtcagggcca ggccagccag gatggtgaag gtcaggatga
    46921 atttgtcttt cagatttcga aagatgagta tcttgatttg ctctttgaag atttggcctt
    46981 accgaatctg aaacaaaacc aacaacgcca gctgaccgaa tataaaacgc atcgggcggg
    47041 ttatactgct aacggcgttc cggccaatat cagcgttgtg cgttccttgc agaactcact
    47101 ggcgcgacgc acagccatga cggcaggcaa gcggcgggaa cttcatgcac tggaagagaa
    47161 tttggccatc atcagcaaca gtgaacctgc gcagctgctg gaagaggaac gtctgcgcaa
    47221 agaaattgca gaattacgtg ccaaaattga acgcgtccct tttattgaca ccttcgattt
    47281 acgttacaag aactacgaga agcggcccga tccctccagc caggcagtga tgttttgcct
    47341 gatggacgtt tccggttcaa tggatcaatc cactaaagat atggctaagc gtttttatat
    47401 tctgctgtat ctgttcctca gcagaacgta taagaacgtg gaagtcgtat acatccgcca
    47461 tcatacccag gcgaaagaag tcgatgaaca tgagtttttc tactcgcagg aaacaggcgg
    47521 caccattgtt tccagcgccc tgaaactgat ggatgaggta gtgaaagagc gttataaccc
    47581 ggcacagtgg aatatttacg ctgcacaagc atcggacggc gataactggg ccgatgactc
    47641 tccgctttgc catgaaatcc tggcgaaaaa attattacct gttgttcgtt attacagcta
    47701 tatcgaaatt acccgtcgtg cacatcagac attgtggcga gaatatgagc atctgcaatc
    47761 tactttcgac aactttgcga tgcagcacat ccgcgaccag gatgatattt atccggtgtt
    47821 ccgtgaactg tttcataaac aaaatgcaac agctaaagac taaaactatc agccaggtca
    47881 ttatcgcctg gctgattttt agcttactgt aaattatctc atttattaca tacattagct
    47941 tacaatcgct ttaaatatga cagcataacc tttacataat ttagttccag aaaacaatca
    48001 ttcggaaaaa tgattcagtc aacacgtatt tccatggggt tattctttaa atatttttta
    48061 tcgttaacga aaattgatcc tggtcaaaac tatatatctc tgccatcaat aaaatccagc
    48121 actcacattg ctctcctttt tatggtttct atgggtacac aaaaattaaa agctcaaagc
    48181 ttttttattt tcagtttatt gctgac
//
LOCUS       DAPGUL010000022        47605 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.022, whole genome shotgun sequence.
ACCESSION   DAPGUL010000022 DAPGUL010000000
VERSION     DAPGUL010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 47605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47605
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.022"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            6..81
                     /locus_tag="RHX21_001404"
     tRNA            6..81
                     /locus_tag="RHX21_001404"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:39..41,aa:Thr,seq:ggt)
     gene            121..236
                     /gene="rrf"
                     /locus_tag="RHX21_001405"
     rRNA            121..236
                     /gene="rrf"
                     /locus_tag="RHX21_001405"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            complement(467..1225)
                     /locus_tag="RHX21_001406"
     CDS             complement(467..1225)
                     /locus_tag="RHX21_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDV1986618.1"
                     /translation="MSQILLQPANAMITLENVNKWYGQFHVLKNINLTVQPGERIVLC
                     GPSGSGKSTTIRCINHLEEHQQGRIVVDGIELNEDIRNIERVRQEVGMVFQHFNLFPH
                     LTVLQNCTLAPIWVRKMPKKEAEALAMHYLERVRIAEHAHKFPGQISGGQQQRVAIAR
                     SLCMKPKIMLFDEPTSALDPEMVKEVLDTMIGLAQSGMTMLCVTHEMGFARTVADRVI
                     FMDRGEIVEQAAPDEFFAHPKSERTRAFLSQVIH"
     gene            complement(1233..2336)
                     /locus_tag="RHX21_001407"
     CDS             complement(1233..2336)
                     /locus_tag="RHX21_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709065.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDV1986619.1"
                     /translation="MTKVLLSQPSRPASHNSSRAMVWVRKNLFSSWSNSLLTIGCIWL
                     MWELIPPLLNWAFLQANWVGSTRADCTKAGACWVFIHERFGQFMYGLYPHDQRWRINL
                     ALLIGLVSIAPMFWKILPHRGRYIAVWAVIYPLIVWWLMYGGFFGLERVETRQWGGLT
                     LTLIIASVGIAGALPWGILLALGRRSHMPIVRILSVIFIEFWRGVPLITVLFMSSVML
                     PLFMAEGTNIDKLIRALVGVILFQSAYVAEVVRGGLQALPKGQYEAAESLALGYWKTQ
                     GLVILPQALKLVIPGLVNTIIALFKDTSLVIIIGLFDLFSSVQQATVDPTWLGMSTEG
                     YVFAALIYWIFCFSMSRYSQHLEKRFNTGRTPH"
     gene            complement(2346..3527)
                     /locus_tag="RHX21_001408"
     CDS             complement(2346..3527)
                     /locus_tag="RHX21_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDV1986620.1"
                     /translation="MSHRRSTVKGSLSFANPTVRAWLFQILAVVAVVGIVGWLFHNTV
                     TNLNNRGITSGFAFLDRGAGFGIVQHLIDYQQGDTYGRVFIVGLLNTLLVSALCIVFA
                     SVLGFFIGLARLSDNWLLRKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSA
                     FDLAFLSNRGLYIPSPQLGDGFIAFILAVVMAIVLSVGLFRFNKTYQIKTGQLRRTWP
                     IAAVLIIGLPLLAQWLFGAALHWDVPALRGFNFRGGMVLIPELAALTLALSVYTSAFI
                     AEIIRAGIQAVPYGQHEAARSLGLPNPVTLRQVIIPQALRVIIPPLTSQYLNIVKNSS
                     LAAAIGYPDMVSLFAGTVLNQTRQAIETIAMTMSVYLIISLTISLLMNIYNRRIAIVE
                     R"
     gene            complement(3595..4620)
                     /locus_tag="RHX21_001409"
     CDS             complement(3595..4620)
                     /locus_tag="RHX21_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HDV1986621.1"
                     /translation="MKKMMIATLAAASVLLAVANQAHAGATLDAVQKKGFVQCGISDG
                     LPGFSYADADGKFSGIDVDVCRGVAAAVFGDDTKVKYTPLTAKERFTALQSGEVDLLS
                     RNTTWTSSRDAGMGMAFTGVTYYDGIGFLTHDKAGLKSAKELDGATVCIQAGTDTELN
                     VADYFKANNMKYTPVTFDRSDESAKALESGRCDTLASDQSQLYALRIKLSNPAEWIVL
                     PEVISKEPLGPAVRRGDDEWFSIVRWTLFAMLNAEEMGINSQNVDEKAANPATPDMAH
                     LLGKEGDYGKDLKLDNKWAYNIIKQVGNYSEIFERNVGSESPLKIKRGQNNLWNNGGI
                     QYAPPVR"
     gene            complement(5051..5272)
                     /locus_tag="RHX21_001410"
     CDS             complement(5051..5272)
                     /locus_tag="RHX21_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986622.1"
                     /translation="MKRLIPVALLTALLAGCAHDSPCVPVYDDQGRLVHTNTCMKGTT
                     QDNWETAGAIAGGAAAVAGLTMGIIALSK"
     gene            complement(5525..8628)
                     /gene="acrF"
                     /locus_tag="RHX21_001411"
                     /pseudo
     CDS             complement(5525..8628)
                     /gene="acrF"
                     /locus_tag="RHX21_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417732.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit AcrF"
     gene            complement(8640..9797)
                     /gene="acrE"
                     /locus_tag="RHX21_001412"
     CDS             complement(8640..9797)
                     /gene="acrE"
                     /locus_tag="RHX21_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter periplasmic
                     adaptor subunit AcrE"
                     /protein_id="HDV1986623.1"
                     /translation="MTKHARFFLLPSFILISAALIAGCNDKGEEKAHVGEPQVTVHIV
                     KTAPLEVKTELPGRTNAYRIAEVRPQVSGIVLNRNFTEGSDVQAGQSLYQIDPATYQA
                     NYDSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVIAAK
                     ATVESARINLAYTKVTAPISGRIGKSTVTEGALVTNGQTTELATVQQLDPIYVDVTQS
                     SNDFMRLKQSVEQGNLHKENATSNVELVMENGQTYPLKGTLQFSDVTVDESTGSITLR
                     AVFPNPQHTLLPGMFVRARIDEGVQPDAILIPQQGVSRTPRGDATVLIVNDKSQVEAR
                     PVVASQAIGDKWLISEGLKSGDQVIVSGLQKARPGEQVKATTDTPADTASK"
     gene            10196..10858
                     /gene="acrS"
                     /locus_tag="RHX21_001413"
     CDS             10196..10858
                     /gene="acrS"
                     /locus_tag="RHX21_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter transcriptional
                     repressor AcrS"
                     /protein_id="HDV1986624.1"
                     /translation="MAKRTKAEALKTRQELIETAIAQFAQHGVSKTTLNDIADAANVT
                     RGAIYWHFENKTQLFNEMWLQQPSLRELIQEHLTAGLEHDPFQQLREKLIVGLQYIAK
                     IPRQQALLKILYHKCEFNDEMLAEGVIREKMGFNPQTLREVLQACQQQGCVANNLDLD
                     VVMIIINGAFSGIVQNWLMNMAGYDLYKQAPALVDNVLRMFMPDENITKLIHQTNELS
                     VM"
     gene            complement(10861..11040)
                     /locus_tag="RHX21_001414"
     CDS             complement(10861..11040)
                     /locus_tag="RHX21_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2556 family protein"
                     /protein_id="HDV1986625.1"
                     /translation="MIRKYWWLVVFAVFVFLFDTLLMQWIELLATETDKCRNMNSVNP
                     LKLVNCDELNFQDRM"
     gene            complement(11124..12008)
                     /gene="yhdJ"
                     /locus_tag="RHX21_001415"
     CDS             complement(11124..12008)
                     /gene="yhdJ"
                     /locus_tag="RHX21_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417728.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine-specific DNA-methyltransferase"
                     /protein_id="HDV1986626.1"
                     /translation="MRTGCEPTRFGNEAKTIIHGDALAELKKIPAESVDLIFADPPYN
                     IGKNFDGLIEAWKEDLFIDWLFEVIAECHRVLKKQGSMYIMNSTENMPFIDLQCRKLF
                     TIKSRIVWSYDSSGVQAKKHYGSMYEPILMMVKDAKNYTFNGDAILVEAKTGSQRALI
                     DYRKNPPQPYNHQKVPGNVWDFPRVRYLMDEYENHPTQKPEALLKRIILASSNPGDIV
                     LDPFAGSFTTGAVAVSSGRKFIGIEINSEYIKMGLRRLDVASHYSAEELAKVKKRKTG
                     NLSKRSRLSEVDPDLIAK"
     gene            12275..13504
                     /locus_tag="RHX21_001416"
     CDS             12275..13504
                     /locus_tag="RHX21_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020457636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDV1986627.1"
                     /translation="MANDKLSDMKLRALMRADVTKPKTIADGAGLSIRVTPSQKQTGN
                     DDKRPTNNLLWLFRYRNPHKSTNPLTLVLGRYPDLSLSAARAQRDKCKSWLADNLDPK
                     DQYKLTSTETLNPVTVRQALQYWVDNYAVHNRANYQRHQAQLDKHIFPYIGDMPLSLC
                     ETKHWLSCFDRTKKKSPVAAGYIFQMCKQALKYCRVRRYAFSNALDDLAIPDVGQKQA
                     KRDRVHSEAELADICNAITSETFFLPYYNALLKILLVFGARTNEVRLSETKEWDVKTW
                     VWTVPKEHAKGGEKIVRPVPEAIRPFILDLIEQHKDTGLLLGELKNPEAVSQWGRSIY
                     KRLGHSEPWTLHDLRRTFSTTLNDMGVAPHIVEGLLGHALGGVMAIYNRSQYLPEKLD
                     ALNKWVDKLSDLQKITN"
     gene            13843..14022
                     /locus_tag="RHX21_001417"
     CDS             13843..14022
                     /locus_tag="RHX21_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001439227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family phage regulatory protein"
                     /protein_id="HDV1986628.1"
                     /translation="MEMLTTKQVCALTTLSRVTIWRYEVSGMFPARVQLGPKRVAWHK
                     AEVEAWMKSRQPVQR"
     gene            14031..14312
                     /locus_tag="RHX21_001418"
     CDS             14031..14312
                     /locus_tag="RHX21_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986629.1"
                     /translation="MKQVTTAEAIRNYNGLLRNPLRQLTVGELTAQRMAAAQSLLQAC
                     IREGVNRPWTIVSRHAAMADSLVPFRISDSESWAMYLELKRGVRNEKRA"
     gene            14296..15984
                     /locus_tag="RHX21_001419"
     CDS             14296..15984
                     /locus_tag="RHX21_001419"
                     /inference="COORDINATES: protein motif:HMM:NF017116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986630.1"
                     /translation="MRNAPNVKLLPKDPFTEAIIFAGSDAWSHAKGWEEGMGKQVAGD
                     TTPPVYLGPRQLADLDNLRIIDDGRRSARVYLAGDIEQLQISTIADKLAVAGVKEARL
                     FKGIPDREPEKWNMDRLRDAALRGESLVGMLRKEERATAAATAKDIHDMTPVLMTTWP
                     NIGSNGQPLNTRPNVERLLDNYSISAKYNEISKDVEVLVPGVSSGSDARDNCAVSEIL
                     SLAALNRLPMSNIEGHIKTIAVRNTYNPVRDFINQREWDGRSRFADLLNTISTPDDYS
                     RDLLAMLVRRWLLSAVAAAYLEAGFWSKGVLVFQGEQSLGKTAWFKALLPPDNRNLVK
                     VGATIDPSNKDSVASAISHWLVELGELDATFRKADIAKLKAFISQDRDDLRRPYDRLE
                     SKYQRRTVFFASVNPKHFLADDTGNVRWWTIPVTAVNYEHGIDTQQLWAEVLSWFEAG
                     ERWWLDRDEEAMLEVVNEQHGQTDPIEEMILARFDWNSDRLAAYIEMTATDVLLSIGQ
                     DRPTKSQATQCGNILRKLTGRDARRTSKGRFYLMPPKVFGQQDHSYFDGPNRQF"
     gene            15994..16218
                     /locus_tag="RHX21_001420"
     CDS             15994..16218
                     /locus_tag="RHX21_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986631.1"
                     /translation="MSYRVYIIAFDPEHGTYTETEIMEGFATEQEAVDHARNRLPEVQ
                     QELAKLGENLLCSYRIRVVDSAEILPFLRS"
     gene            16979..17890
                     /locus_tag="RHX21_001421"
     CDS             16979..17890
                     /locus_tag="RHX21_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001536343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986632.1"
                     /translation="MNDVLSGLIRAALEHQGAHLRFDGNGDINQVIPVEPAAVRYLSL
                     NEVLTPKAGSQTTFNGIIAARSLVAAAGAEIIRIPGPMTQQADIDDEGNRRPLKQQEV
                     PRHYIVVAPGKFAAVADDAEITLSDAPYLVASYDDATAPSYGIGYTLTRQQLKHTFAD
                     PDTVLRAVNSAIEQGIARLADSVLLTDLNTKAATLTDATVDAVAKAAAAKGCRWADLS
                     AIAGTSAAGVTLGGDGTLRACAVKAELTDTIATTIVGDFSRAAVAIDDELRVTAKRIN
                     NGAVEIVVWCNAQALVPDSAYFWKYGA"
     gene            17893..18207
                     /locus_tag="RHX21_001422"
     CDS             17893..18207
                     /locus_tag="RHX21_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001536348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986633.1"
                     /translation="MGWGIKKVAAERAALSGEVLAAIEGAAMYTRHGDAEAPRIIVQP
                     AGYTGFIYSEEAAEKWVRRAFIELTPYQVERAVNYLASLVREHHREHQPKRQRNSWVN
                     RW"
     gene            18210..18377
                     /locus_tag="RHX21_001423"
     CDS             18210..18377
                     /locus_tag="RHX21_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986634.1"
                     /translation="MSKENAARQHVTVRLAPELVRQVERERTKLERRTGIRPSRSQVI
                     EKFLSSGLNGK"
     gene            18593..18910
                     /locus_tag="RHX21_001424"
     CDS             18593..18910
                     /locus_tag="RHX21_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000788502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986635.1"
                     /translation="MKNHDLYESMKEEARLILSETKRFQTISEKNPISYEAADLLASL
                     RNRLNAFENMTDEAGRIMRDEAESNASTLERKKWKPSSRISSGERAKRQAVKRGAILV
                     RGA"
     gene            18913..19122
                     /locus_tag="RHX21_001425"
     CDS             18913..19122
                     /locus_tag="RHX21_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986636.1"
                     /translation="MATNNNIYDAVLNVIGVADKMTNNNASQLTDAQKAALKNLSNAM
                     KSWKGITFGMRDITASDKPIDSKTA"
     gene            19132..19338
                     /locus_tag="RHX21_001426"
     CDS             19132..19338
                     /locus_tag="RHX21_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986637.1"
                     /translation="MLDRIHRKPEGMNPWPELVDAVLPKVLVCNTAEEMQEQRDYRTE
                     CALQLAAAALRAAGEHTLAENLLN"
     gene            19360..21639
                     /locus_tag="RHX21_001427"
     CDS             19360..21639
                     /locus_tag="RHX21_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDV1986638.1"
                     /translation="MANKKLNATITIGGAVSGSLRGAFGTVKKSTVEIGSAITHLSRE
                     QRQLNEAMKRYGQNSVMVDRLRGRYDAIVGQVERLRKAQERLNAVERASAANLAKRAE
                     LRGQMLDTVALGAAVAAPIKIAADRESHAVGIAKQLQGARDEAGKLTPVFWQMRKAVT
                     DLGHEIPLATNDLYDMAAAGLRMGVASNDILGFTRNTAKLAAALELDPGETAERFAKL
                     GTVFKLSQDQLMGLGDAINYLDDQTTAKGGEIIDFMARVGGSAGLVKITAGQVAAIGT
                     ALISMGETAETAGTSTAALFSKLAMGDKNTKAAREAFKELGLSAGQMSKAVQKDAIGA
                     MEMLFDRVRKLPEASRTGVLVDIFGQEHVGKIAKLVTGTKELASALEAVNGEASKGSV
                     HKEFQNTISTTNAQMVLLSNRMADVADNIGTVLLPSVNDAASTIGKFTTVVANFAQEH
                     PGLTKAVVGTAVALTSLKVATLAGGYAFTFLKGGALMVAKGLAGARAEMALTATGARL
                     MGASAAVARGGVIGLGRALVMNPIGAIAAGIAVAGLAIYKNWDMVKAAAIGFGRGMLE
                     GLQPVSDAISTVRQALTPLEPAFKVVGDAVKGVFNWFSNLLEPTKHTSDQLKSATDAG
                     QTFGKVVGEAISFVLTPLTALVDGFKWISENGGKILNTVGATIDKAKSWLPSWAGGTD
                     DDAPKAATPPGLTPPPAPAMANRSGSTSYTTEQTNHFTIHAAPGMNEDALARKVAETL
                     KRQQAVRGRSMMTDGAYQP"
     gene            complement(21723..22019)
                     /gene="fis"
                     /locus_tag="RHX21_001428"
     CDS             complement(21723..22019)
                     /gene="fis"
                     /locus_tag="RHX21_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001465625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator Fis"
                     /protein_id="HDV1986639.1"
                     /translation="MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNG
                     QDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN"
     gene            complement(22045..23010)
                     /gene="dusB"
                     /locus_tag="RHX21_001429"
     CDS             complement(22045..23010)
                     /gene="dusB"
                     /locus_tag="RHX21_001429"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HDV1986640.1"
                     /translation="MRIGQYQLRNRLIAAPMAGITDRPFRTLCYEMGAGLTVSEMMSS
                     NPQVWESDKSRLRMVHIDEPGIRTVQIAGSDPKEMADAARINVESGAQIIDINMGCPA
                     KKVNRKLAGSALLQYPDVVKSILTEVVNAVDVPVTLKIRTGWAPEHRNCEEIAQLAED
                     CGIQALTIHGRTRACLFNGEAEYDSIRAVKQKVSIPVIANGDITDPLKARAVLDYTGA
                     DALMIGRAAQGRPWIFREIQHYLDTGELLPPLPLAEVKRLLCAHVRELHDFYGPAKGY
                     RIARKHVSWYLQEHAPNDQFRRTFNAIEDASEQLEALEAYFENFA"
     gene            complement(23339..24220)
                     /gene="prmA"
                     /locus_tag="RHX21_001430"
     CDS             complement(23339..24220)
                     /gene="prmA"
                     /locus_tag="RHX21_001430"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HDV1986641.1"
                     /translation="MPWIQLKLNTTGANAEDLSDALMEAGAVSITFQDTHDTPVFEPL
                     PGETRLWGDTDVIGLFDAETDMNDVVAILENHPLLGAGFAHKIEQLEDKDWEREWMDN
                     FHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDSLDLTGK
                     TVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQ
                     PEEMKADVVVANILAGPLRELAPLISVLPVSGGLLGLSGILASQAESVCEAYADSFAL
                     DPVVEKEEWCRITGRKN"
     gene            complement(24232..25683)
                     /gene="panF"
                     /locus_tag="RHX21_001431"
     CDS             complement(24232..25683)
                     /gene="panF"
                     /locus_tag="RHX21_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312157.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/pantothenate symporter"
                     /protein_id="HDV1986642.1"
                     /translation="MQLEVILPLVAYLVVVFGISVYAMRKRSTGTFLNEYFLGSRSMG
                     GIVLAMTLTATYISASSFIGGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILA
                     RRYNAVTLNDMLFARYQSRLLVWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYET
                     GLLIFGISIALYTAFGGFRASVLNDTMQGLVMLIGTVVLLIGVVHAAGGLSNAVQTLQ
                     TIDPQLVTPQGADDILSPAFMTSFWVLVCFGVIGLPHTAVRCISYKDSKAVHRGIIIG
                     TIVVAILMFGMHLAGALGRAVIPDLTVPDLVIPTLMVKVLPPFAAGIFLAAPMAAIMS
                     TINAQLLQSSATIIKDLYLNIRPDQMQNETRLKRMSAVITLVLGALLLLAAWKPPEMI
                     IWLNLLAFGGLEAVFLWPLVLGLYWERANAKGALSAMIVGGVLYAVLATLNIQYLGFH
                     PIVPSLLLSLLAFLVGNRFGTSVPQATVLTTDK"
     gene            complement(25673..25915)
                     /locus_tag="RHX21_001432"
     CDS             complement(25673..25915)
                     /locus_tag="RHX21_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdT family protein"
                     /protein_id="HDV1986643.1"
                     /translation="MDTRFVQAHKEARWALGLTLLYLAVWLVAAYLPGVAPGFTGFPR
                     WFEMACILTPLLFIGLCWAMVKFIYRDIPLEDDDAA"
     gene            complement(26024..27373)
                     /gene="accC"
                     /locus_tag="RHX21_001433"
     CDS             complement(26024..27373)
                     /gene="accC"
                     /locus_tag="RHX21_001433"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009483995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HDV1986644.1"
                     /translation="MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLL
                     ADETVCIGPAPSVKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIF
                     IGPKADTIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKA
                     SGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFNNDMVYMEKYLENPRHVEIQVLADG
                     QGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFE
                     FLFENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHA
                     VECRINAEDPNTFLPSPGKITRFHAPGGFGVRWESHIYAGYTVPPYYDSMIGKLICYG
                     ENRDVAIARMKNALQELIIDGIKTNVDLQIRIMNDENFQHGGTNIHYLEKKLGLQEK"
     gene            complement(27384..27854)
                     /gene="accB"
                     /locus_tag="RHX21_001434"
                     /gene_synonym="fabE"
     CDS             complement(27384..27854)
                     /gene="accB"
                     /locus_tag="RHX21_001434"
                     /gene_synonym="fabE"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HDV1986645.1"
                     /translation="MDIRKIKKLIELVEESGISELEISEGEESVRISRAAPAASFPVM
                     QQAYAAPMMQQPAQSNAAAPATVPSMEAPAAAEISGHIVRSPMVGTFYRTPSPDAKAF
                     IEVGQKVNVGDTLCIVEAMKMMNQIEADKSGTVKAILVESGQPVEFDEPLVVIE"
     gene            complement(28832..29806)
                     /locus_tag="RHX21_001435"
     CDS             complement(28832..29806)
                     /locus_tag="RHX21_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDV1986646.1"
                     /translation="MQALLLEQQDGKTLASVQTLDESRLPEGDVTVDVHWSSLNYKDA
                     LAITGKGKIIRNFPMIPGIDFAGTVRTSEDPRFHAGQEVLLTGWGVGENHWGGLAEQA
                     RVKGDWLVAMPQGLDARKAMIIGTAGFTAMLCVMALEDAGVRPQDGEIVVTGASGGVG
                     STAVALLHKLGYQVVAVSGRESTHEYLKSLGASRILPRDEFAESRPLEKQVWAGAIDT
                     VGDKVLAKVLAQMNYGGCVAACGLAGGFTLPTTVMPFILRNVRLQGVDSVMTPPERRA
                     QAWQRLVADLPESFYTQAAKEISLSEAPNFAEAIINNQIQGRTLVKVN"
     gene            29958..31898
                     /gene="csrD"
                     /locus_tag="RHX21_001436"
     CDS             29958..31898
                     /gene="csrD"
                     /locus_tag="RHX21_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase E specificity factor CsrD"
                     /protein_id="HDV1986647.1"
                     /translation="MRLTTKFSAFVTLLTGLTIFVTLLGCSLSFYNAIQYKFSHRVQA
                     VATAIDTHLVSNDFSTLRPQITELMMSADIVRVDLLHGDKQVYTLARNGSYRPVGSSD
                     LFRELSVPLIKHPGMSLRLVYQDPMGNYFHSLMTTAPLTGAIGFIIVMLFLAVRWLQR
                     QLAGQELLETRATRILNGERGSNVLGTIYEWPPRTSSALDTLLREIQNAREQHSRLDT
                     LIRSYAAQDVKTGLNNRLFFDNQLATLLEDQEKVGTHGIVMMIRLPDFNMLSDTWGHS
                     QVEEQFFTLTNLLSTFMMRYPGALLARYHRSDFAALLPHRTLKEAESIAGQLIKAVDT
                     LPNNKMLDRDDMIHIGICAWRSGQDTEQVMEHAESATRNAGLQGGNSWAIYDDSLPEK
                     GRGNVRWRTLIEQMLSRGGPRLYQKPAVTREGQVHHRELMCRIFDGNEEVSSAEYMPM
                     VLQFGLSEEYDRLQISRLIPLLRYWPEENLAIQVTVESLIRPRFQRWLRDTLMQCEKS
                     QRKRIIIELAEADVGQHISRLQPVIRLVNALGVRVAVNQAGLTLVSTSWIKELNVELL
                     KLHPGLVRNIEKRTENQLLVQSLVEACSGTSTQVYATGVRSRSEWQTLIQRGVTGGQG
                     DFFASSQPLDTNVKKYSQRYSV"
     gene            32203..33246
                     /gene="mreB"
                     /locus_tag="RHX21_001437"
     CDS             32203..33246
                     /gene="mreB"
                     /locus_tag="RHX21_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000913396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreB"
                     /protein_id="HDV1986648.1"
                     /translation="MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQD
                     RAGSPKSVAAVGHDAKQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNS
                     FMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATG
                     SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERI
                     KHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALE
                     QCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALE
                     MIDMHGGDLFSEE"
     gene            33312..34415
                     /gene="mreC"
                     /locus_tag="RHX21_001438"
     CDS             33312..34415
                     /gene="mreC"
                     /locus_tag="RHX21_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HDV1986649.1"
                     /translation="MKPIFSRGPSLQIRLILAVLVALGIIIADSRLGTFSQIRTYMDT
                     AVSPFYFVSNAPRELLDGVSQTLASRDQLELENRALRQELLLKNSELLMLGQYKQENA
                     RLRELLGSPLRQDEQKMVTQVISTVNDPYSDQVVIDKGSVNGVYEGQPVISDKGVVGQ
                     VVAVAKLTSRVLLICDATHALPIQVLRNDIRVIAAGNGCTDDLQLEHLPANTDIRVGD
                     VLVTSGLGGRFPEGYPVAVVSSVKLDTQRAYTVIQARPTAGLQRLRYLLLLWGADRNG
                     ANPMTPEEVHRVANERLMQMMPQVLPSPDAMGPKLPEPATGIAQPTPQQPTTGNAATA
                     PAAPTQPAANRSPQRATPPQSGAQPPARAPGGQ"
     gene            34415..34903
                     /gene="mreD"
                     /locus_tag="RHX21_001439"
     CDS             34415..34903
                     /gene="mreD"
                     /locus_tag="RHX21_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001487551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HDV1986650.1"
                     /translation="MASYRSQGRWVIWLSFLIALLLQIMPWPDNLIVFRPNWVLLILL
                     YWILALPHRVNVGTGFVMGAILDLISGSTLGVRVLAMSIIAYLVALKYQLFRNLALWQ
                     QALVVMLLSLVVDIIVFWAEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFA
                     VQ"
     gene            34912..35505
                     /gene="yhdE"
                     /locus_tag="RHX21_001440"
     CDS             34912..35505
                     /gene="yhdE"
                     /locus_tag="RHX21_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase YhdE"
                     /protein_id="HDV1986651.1"
                     /translation="MTSLYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQY
                     VVRLAREKAQAGVAQTAQDLPVLGADTIVILNGEVLEKPRDAEHAAQMLRKLSGQTHQ
                     VMTAVALADSQHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFV
                     RKINGSYHAVVGLPLVETYELLSNFNALREKRDKHDG"
     gene            35495..36964
                     /gene="rng"
                     /locus_tag="RHX21_001441"
     CDS             35495..36964
                     /gene="rng"
                     /locus_tag="RHX21_001441"
                     /EC_number="3.1.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease G"
                     /protein_id="HDV1986652.1"
                     /translation="MTAELLVNVTPSETRVAYIDGGILQEIHIEREARRGIVGNIYKG
                     RVSRVLPGMQAAFVDIGLDKAAFLHASDIMPHTECVAGEEQKQFTVRDISELVRQGQD
                     LMVQVVKDPLGTKGARLTTDITLPSRYLVFMPGASHVGVSQRIESESERERLKKVVAE
                     YCDEQGGFIIRTAAEGVGEAELASDAAYLKRVWTKVMERKKRPQTRYQLYGELALAQR
                     VLRDFADAELDRIRVDSRLTYEALLEFTSEYIPEMTSKLEHYTGRQPIFDLFDVENEI
                     QRALERKVELKSGGYLIIDQTEAMTTVDINTGAFVGHRNLDDTIFNTNIEATQAIARQ
                     LRLRNLGGIIIIDFIDMNNEDHRRRVLHSLEQALSKDRVKTSVNGFSALGLVEMTRKR
                     TRESIEHVLCNECPTCHGRGTVKTVETVCYEIMREIVRVHHAYDSDRFLVYASPAVAE
                     ALKGEESHSLAEVEIFVGKQVKVQIEPLYNQEQFDVVMM"
     gene            37032..40832
                     /gene="yhdP"
                     /locus_tag="RHX21_001442"
     CDS             37032..40832
                     /gene="yhdP"
                     /locus_tag="RHX21_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA2 domain-containing protein YhdP"
                     /protein_id="HDV1986653.1"
                     /translation="MRRLPGILLLTGAALVVIAALLVSGLRIALPHLDAWRPEILNKI
                     ESATGMPVEASQLSASWQNFGPTLEAHDIRAELKDGGEFSVKRVTLALDVWQSLLHMR
                     WQFRDLTFWQLRFRTNTPITSGGGNDSLEASHISDLFLRQFDHFDLRDSEVSFLTPSG
                     QRAELAIPQLTWLNDPRRHRAEGLVSLSSLTGQHGVMQVRMDLRDDEGLLSNGRVWLQ
                     ADDIDLKPWLGKWMQDNIALETAQFSLEGWMTIDKGDVTGGDVWLKQGGASWLGEKQT
                     HTLSVDNLTAHITRENPGWQFSIPDTRITMDGKPWPSGALTLAWVPEQDVGGKDNKRS
                     DELRIRASNLELAGLEGIRPLAAKLSPALGDVWRSTQPSGKINTLALDIPLQAADKTR
                     FQASWSDLAWKQWKLLPGAEHFSGTLSGSVENGLLTASMKQAKMPYETVFRAPLEIAD
                     GQATISWLNNDKGFQLDGRNIDVKAKAVHARGGFRYLQPANDEPWLGILAGISTDDGS
                     QAWRYFPENLMGKDLVDYLSGAIQGGEADNATLVYGGNPQLFPYKHNEGQFEVLVPLR
                     NAKFAFQPDWPALTNLDIELDFINDGLWMKTDGVNLGGVRASNLTAVIPDYSKEKLLI
                     DADIKGPGKAVGPYFDETPLKDSLGATLQELQLDGDVNARLHLDIPLNGELVTAKGEV
                     TLRNNSLFIKPLDSTLKNLSGKFSFINSDLQSEPLTASWFNQPLNVDFSTKEGAKAYQ
                     VAVNLNGNWQPAKTGVLPEAVNEALSGSVAWDGKVGIDLPYHAGATYNIELNGDLKNV
                     SSHLPSPLAKPAGEPLAVNVKVDGNLNSFELTGQAGADNHFNSRWLLGQKLTLDRAIW
                     AADSKTLPPLPEQSGVELNMPPMNGAEWLALFQKGAAESVGGAASFPQHITLRTPMLS
                     LGNQQWNNLSIVSQPTANGTLVEAQGREINATLAMRNNAPWLANIKYLYYNPSVAKTR
                     GDSTPSSPFPTTERINFRGWPDAQIRCTECWFWGQKFGRIDSDITISGDTLTLTNGLI
                     DTGFSRLTADGEWVNNPGNERTSLKGKLRGQKIDAAAEFFGVTTPIRQSSFNVDYDLH
                     WRKAPWQPDEATLNGIIHTQLGKGEITEINTGHAGQLLRLLSVDALMRKLRFDFRDTF
                     GEGFYFDSIRSTAWIKDGVMHTDDTLVDGLEADIAMKGSVNLVRRDLNMEAVVAPEIS
                     ATVGVAAAFAVNPIVGAAVFAASKVLGPLWSKVSILRYHISGPLDDPQINEVLRQPRK
                     EKAQ"
     gene            40988..42433
                     /gene="tldD"
                     /locus_tag="RHX21_001443"
     CDS             40988..42433
                     /gene="tldD"
                     /locus_tag="RHX21_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease TldD"
                     /protein_id="HDV1986654.1"
                     /translation="MSLNLVSEQLLAANGLKHQDLFAILGQLAERRLDYGDLYFQSSY
                     HESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIVRD
                     SGDGKVQTLGAVEHSPLYTSVDPLQSMSREEKLDILRRVDKVAREADKRVQEVTASLS
                     GVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGASGGGGRFGYEFFLADLD
                     GEVRADAWAKEAVRMALVNLSAVAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRR
                     GTSVFSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQYNVLIENGILKGYMQ
                     DKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFG
                     GGQVDITSGKFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNG
                     VGVCGKEGQSLPVGVGQPTLKVDNLTVGGTA"
     gene            complement(42561..43490)
                     /gene="aaeR"
                     /locus_tag="RHX21_001444"
     CDS             complement(42561..43490)
                     /gene="aaeR"
                     /locus_tag="RHX21_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator AaeR"
                     /protein_id="HDV1986655.1"
                     /translation="MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDEL
                     QVKLLNRSTRSIGLTEAGRIYYQGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTM
                     AQNVLAGLTAKMLKEYPGLSVNLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGA
                     MPMVVCAAKSYLTQYGIPEKPADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRF
                     VTNDPMTLVRWLTAGAGIAYVPLMWVINEINRGELEILLPRYQSDPRPVYALYTEKDK
                     LPLKVQVVINSLTDYFVEVGKLFQEMHGRGKEK"
     gene            43673..43876
                     /locus_tag="RHX21_001445"
     CDS             43673..43876
                     /locus_tag="RHX21_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AaeX family protein"
                     /protein_id="HDV1986656.1"
                     /translation="MSLFPVIVVFGLSFPPIFFELLLSLAIFWLVRRVLVPTGIYDFV
                     WHPALFNTALYCCLFYLISRLFV"
     gene            43884..44816
                     /gene="aaeA"
                     /locus_tag="RHX21_001446"
     CDS             43884..44816
                     /gene="aaeA"
                     /locus_tag="RHX21_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-hydroxybenzoic acid efflux pump subunit AaeA"
                     /protein_id="HDV1986657.1"
                     /translation="MKTLIRKFSRTAITVVLVILAFIAIFNAWVYYTESPWTRDARFS
                     ADVVAIAPDVSGLITQVNVHDNQLVKKGQILFTIDQPRYQKALEEAQADVAYYQVLAQ
                     EKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAP
                     ADGWVTNLNVYTGEFITRGSTAVALVKQNSFYVLAYMEETKLEGVRPGYRAEITPLGS
                     NKVLKGTVDSVAAGVTNASSTRDDKGMATIDSNLEWVRLAQRVPVRIRLDNQQENIWP
                     AGTTATVVVTGKQDRDESQDSFFRKMAHRLREFG"
     gene            44822..46789
                     /gene="aaeB"
                     /locus_tag="RHX21_001447"
     CDS             44822..46789
                     /gene="aaeB"
                     /locus_tag="RHX21_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-hydroxybenzoic acid efflux pump subunit AaeB"
                     /protein_id="HDV1986658.1"
                     /translation="MGIFSIANQHIRFAVKLATAIVLALFVGFHFQLETPRWAVLTAA
                     IVAAGPAFAAGGEPYSGAIRYRGFLRIIGTFIGCIAGLVIIIAMIRAPLLMILVCCIW
                     AGFCTWISSLVRIENSYAWGLAGYTALIIVITIQPEPLLTPQFAVERCSEIVIGIVCA
                     IMADLLFSPRSIKQEVDRELESLLVAQYQLMQLCIKHGDGEVVDKAWGDLVRRTTALQ
                     GMRSNLNMESSRWARANRRLKAINTLSLTLITQSCETYLIQNTRPELITDTFREFFDT
                     PVETAQDVHKQLKRLRRVIAWTGERETPVTIYSWVAAATRYQLLKRGVISNTKINATE
                     EEILQGEPEVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGSGAMVMIAVVTS
                     LAMRLPNPRMVAIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCISLAVLGFFLGIE
                     VQKRRLGSMGALASTINIIVLDNPMTFHFSQFLDSALGQIVGCVLAFTVILLVRDKSR
                     DRTGRVLLNQFVSAAVSAMTTNVARRKENHLPALYQQLFLLMNKFPGDLPKFRLALTM
                     IIAHQRLRDAPIPVNEDLSAFHRQMRRTADHVISARSDDKRRRYFGQLLEELEIYQEK
                     LRIWQAPPQVTEPVHRLAGMLHKYQHALTDS"
     gene            46881..47153
                     /locus_tag="RHX21_001448"
     CDS             46881..47153
                     /locus_tag="RHX21_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="barstar family protein"
                     /protein_id="HDV1986659.1"
                     /translation="MNIYTFDFDEIESQEDFYRDFSQTFGLAKDKVRDLDSLWDVLMN
                     DVLPLPLEIEFVHLGEKTRRRFGALILLFDEAEEELEGHLRFNVRH"
     gene            complement(47209..47472)
                     /gene="yhcN"
                     /locus_tag="RHX21_001449"
     CDS             complement(47209..47472)
                     /gene="yhcN"
                     /locus_tag="RHX21_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417705.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide/acid stress response protein YhcN"
                     /protein_id="HDV1986660.1"
                     /translation="MKIKTTVAALSVLSVLSFGAFAADSIDAAQAQNREAIGTVSVSG
                     VASSPMDMREMLNKKAEEKGATAYQITEARSGDTWHATAELYK"
BASE COUNT        11877 a        11978 c        12386 g        11364 t
ORIGIN      
        1 agcgtgctga tatggctcag ttggtagagc gcacccttgg taagggtgag gtccccagtt
       61 cgactctggg tatcagcacc actttttagg ttaaagttcg gcagattaga aaagaatttg
      121 tctggcggca gtagcgcggt ggtcccacct gaccccatgc cgaactcaga agtgaaacgc
      181 cgtagcgccg atggtagtgt ggggtctccc catgcgagag tagggaactg ccagacatca
      241 aataaaacaa aaggctcagt cggaagactg ggccttttgt tttatctgtt gtttgtcggt
      301 gaacactctc ccaaccagga caaatccgcc gggagcggat ttgaacgttg cgaagcaacg
      361 gcccggaggg tggcgggcag gacgcccgcc ataaactgcc agacatcaaa tcaagcgaaa
      421 ggccatccga aaggatggcc tttttgcttt tcgaactaac attcaattaa tggattacct
      481 gcgataaaaa tgccctcgta cgctctgatt taggatgcgc aaaaaattca tcaggtgcag
      541 cttgttccac tatctcccca cgatccataa aaattacccg gtcagcgacg gtacgtgcaa
      601 accccatctc atgtgttaca cacaacattg tcatacccga ctgcgccagc ccaatcatcg
      661 tatccagcac ctctttcacc atctccggat cgagcgccga cgttggctca tcaaacaaca
      721 taattttcgg cttcatacac agcgaacgcg caatggcaac gcgttgctgc tgaccaccag
      781 aaatttgtcc gggaaactta tgcgcatgtt cggcaattct cacccgctca aggtaatgca
      841 tcgccagagc ttcagcctct ttctttggca tcttgcgtac ccaaatcggt gccagggtac
      901 agttctgtag aacggtcaga tgagggaaga gattgaaatg ctgaaagacc attcccactt
      961 cctgccggac gcgctcaata ttgcggatat cttcattaag ttcgatgcca tctaccacga
     1021 tccgtccctg ttgatgttct tccagatgat taatacaacg aatggttgtc gatttaccgg
     1081 aacctgaagg gccacacaga acgatccgtt ctcccggttg cacggttaaa tttatatttt
     1141 tcaaaacatg gaattgtcca taccatttat tgacgttttc cagcgtaatc atcgcgttag
     1201 caggttgcag taaaatttgg ctcatagtgt cctcaatgcg gtgtacgccc ggtgttaaaa
     1261 cgtttttcca gatgctggct atagcgcgac atgctgaaac agaagatcca gtagatcagc
     1321 gcggcgaaaa catacccttc cgtcgacata cccaaccagg tgggatcaac ggttgcctgc
     1381 tgaacgctac tgaaaagatc gaacaacccg ataatgatca ccaggctggt atctttgaag
     1441 agtgcgatga tggtatttac cagcccagga attaccagct tcaacgcctg tggcagaata
     1501 accagcccct gagttttcca gtaacccaac gccagcgact ctgccgcttc atattgccct
     1561 ttaggcagcg cctgtaatcc gcctcgcacg acttccgcaa catatgctga ctgaaacagg
     1621 atcacgccaa ccagcgcgcg gatcagtttg tcgatattgg tgccttctgc cataaacaaa
     1681 ggcagcatga ccgaagacat aaacaatacg gtaatcagcg gtacgccgcg ccagaactcg
     1741 ataaaaatga ccgataagat acgcacaatc ggcatatggg agcggcgacc taacgccagt
     1801 aagatccccc acggtagcgc ccccgcaatc ccaacggatg caataattaa agttagcgtc
     1861 agcccgcccc attgccgggt ttcaacccgc tccagaccaa aaaaaccgcc atacatcagc
     1921 caccagacaa tcagtgggta aatcaccgcc cagaccgcaa tatagcgacc gcgatgcggg
     1981 agtattttcc agaacattgg tgcgattgac acaaggccaa tcagtaatgc caggttaatt
     2041 cgccagcgtt ggtcgtgtgg gtaaagtcca tacataaact gaccaaatcg ttcgtggatg
     2101 aagacccaac aggcaccggc ttttgtgcag tcggcacgcg ttgagccaac ccaattagcc
     2161 tgcaaaaatg cccagttcag caacggtggg atcagttccc acatcaacca tatgcagcca
     2221 atagtcagca ggctattgct ccagctggag aacagatttt ttcgcaccca caccatcgcg
     2281 cggcttgagt tatggctcgc tgggcgcgag ggctgagaca gcaatacttt tgtcatcatg
     2341 actccttagc gttcaacgat cgcgatgcgg cggttataga tattcatcag cagcgagata
     2401 gtcaggctga taatcagata gaccgacatg gtcatggcta tcgtctcgat ggcttgcctc
     2461 gtctggttca gcacggtgcc agcaaacagc gaaaccatat cgggatagcc aatagcggcg
     2521 gcaagagagg agtttttgac gatgttgaga tactggctgg ttaacggcgg aataatcact
     2581 cgcagtgcct ggggaataat gacctggcgt agcgtaaccg ggttgggtaa tcccagtgac
     2641 cgagccgctt catgttgacc ataaggcact gcctggatcc cagcgcggat aatctcggcg
     2701 ataaatgcag atgtataaac cgaaagtgcc agcgttaagg ctgccagttc aggaattaaa
     2761 accatcccgc cgcggaagtt aaagcctcgt agggctggga catcccagtg tagtgctgcg
     2821 ccaaaaagcc attgcgccag taaaggcaaa ccaatgatca acactgcggc gatcggccag
     2881 gtgcggcgca gttgtccggt ctttatctgg tatgttttat taaagcggaa tagcccaaca
     2941 gaaaggacta tagccataac aacagccagg ataaacgcaa taaatccgtc tcccagctgc
     3001 ggtgacggaa tataaagccc acgattgctc aaaaaggcca gatcaaacgc gctcacagcc
     3061 tggcgtggtc cgggcaaatt gcgcaacacg gcaaagtacc agaagaagat ttgcagcagc
     3121 gggggaatat tacggaagat ctcaatataa attgtggata gttttcgtag cagccagtta
     3181 tccgaaagtc tcgccagacc gataaagaag cctaaaacag aagcgaacac aatacacaat
     3241 gcagaaacca gtagcgtatt gagtaagccg acaataaaaa cgcgtccgta ggtgtcgccc
     3301 tgctggtaat cgatcaaatg ctggacaata ccgaagccag cgccgcgatc cagaaaggca
     3361 aaacctgaag taatgccacg attattgaga ttcgttacag tgttgtgaaa taaccaacca
     3421 acaatgccga caacagcaac aacggcaagg atctggaata accaggcgcg aaccgtaggg
     3481 ttggcaaaag agagtgagcc tttaacggtt gagcggcgat gagacataga aacctcggaa
     3541 agcataacgc tgaagagagc gccgccgtag cgacgcccgt tacctcacac cgacttaacg
     3601 cacgggcggc gcgtactgaa taccgccgtt attccagaga ttattttgcc cacgtttaat
     3661 tttcagcggg ctttctgaac ctacgttacg ctcgaaaatt tccgagtagt tacccacctg
     3721 tttgatgatg ttataggccc atttattatc cagcttcaga tccttgccgt aatcgccttc
     3781 tttacccagc agatgtgcca tatcaggcgt tgctggatta gccgcttttt catcgacgtt
     3841 ctgggaattg atgcccatct cttcagcatt cagcatggcg aaaagcgtcc agcgtacaat
     3901 cgagaaccat tcatcatcgc cacgacgaac tgccggccca agcggttctt tagagataac
     3961 ctccggtaag acaatccatt cagctgggtt gcttaatttg atgcgcaggg catacagttg
     4021 cgactgatcc gaggccagcg tatcgcagcg accagattcc agtgccttcg ctgattcgtc
     4081 agagcgatcg aaagtcaccg gtgtgtactt catattgttt gccttgaaat agtcggcaac
     4141 gttgagttcg gtatcagtac ccgcctgaat acagacggta gcgccatcca gttctttcgc
     4201 gctttttagc cccgctttat cgtgcgtcag gaagccaatg ccgtcgtaat aagtgacgcc
     4261 ggtaaatgcc attcccatcc cggcatcgcg agatgaagtc caggtcgtat tacgggagag
     4321 caaatccact tcccctgact gtaaagcggt gaagcgttct tttgctgtga gtggggtata
     4381 tttcactttc gtgtcgtcac caaatacagc agcggcaaca ccacgacaaa catcaacatc
     4441 aatacctgaa aacttaccgt ctgcatcggc ataagagaac ccaggtaatc catcactgat
     4501 cccgcattgc acaaaacctt ttttctgaac ggcatcaagc gtcgcgccag catgcgcctg
     4561 atttgcaacg gcaagcagca cgctggcggc agccagtgtg gctatcatca tctttttcat
     4621 aatgcttcct gtgaggcgaa aattatcgtt ataggacgtt tgggaaacgt cttttacctg
     4681 tctgtggcca tcctcttata agcaaaagta gtgccagctt ttgcgcccga tttcgcgtcg
     4741 caataagctg agtgtagaca ggaaataata aaaacagcgc cccgcaatgg tgcgaaaatg
     4801 aaacatgcgc cacattttgg cgcaaaatat ttacgcgtgt tttactaagc agaataatga
     4861 ttgttagcgt gagtatattt ctggtgggaa gtgtgaaagt taaattgatg cgttatttcg
     4921 aaagcagcga aataacgcga tataacatgc taaatcagca gagaattagc cagcagaata
     4981 tagcaatatt ttatcttatg taaagatact gtatcgttaa acagagcgcg aaactccgcg
     5041 ccctgttcag ttatttcgac agagcgatga tccccatcgt caggccagca acagccgctg
     5101 ccccgccagc aatagcccca gccgtttccc agttatcctg agtcgtgcct ttcatacagg
     5161 tattggtgtg aaccagacga ccctgatcgt cataaaccgg aacgcagggc gaatcgtgag
     5221 cacagcccgc cagcaatgcg gtgagcaatg ccacaggaat taatcttttc atggtgttac
     5281 ctcagtaata aacgctaacg cttaataagt taactctctt attaacgagc tgaatgccat
     5341 tttatcaccg gaggttataa atcttgcgga atgaataatg acaaattatg tgaattgtaa
     5401 aaatagtgaa gggagcggga actatagaaa gcttttaaag agtgagcaga agaatatctt
     5461 attaattttt atgggtttca ctggaaataa taaaggcacc cgaaagcgcc tttatgtttc
     5521 tgatttatcc tttaaagcaa cggcggatca ccacaaagaa caccggtacg aagaagattg
     5581 ccagcaacgt tgcagagacc attcctccca ttaccccgat acccacagcg ttctgcgcgc
     5641 cactgccggc accgttactg atagctagcg gtaatacgcc gagaataaag gcgagagagg
     5701 tcatcaggat aggacgcaga cgcatacgta ctgccatcag tgtcgcttca acaacacctt
     5761 taccctcttt ctccatgaga tctttagcga actcaacaat caaaatagcg tttttggccg
     5821 acaagccaat tgtcgttagc aagcccacca taaagtagac gtcatttttt tgattaaaga
     5881 gtgttgccgc cagtagcacg ccgacaatcc ctaacggcac taccaacata accgagacag
     5941 gaattgacca gctttcatag agtgcagcaa ggcacaggaa aacaaccaca aaggaaattg
     6001 ctaccagagc gggagcctgg tttcccgata agcgttcctg atacgacata cccgtccagt
     6061 cataaccaat gcccgcaggt aattttgacg caaggttttc catcaacgcc atggcatcgc
     6121 cggaactggt tcctggcgcg gcttccccct gaatctccat tgacggcaga ccgttgtagc
     6181 gttccagtcg cggagagcca tacacccaat gtgaagtggt aaaggccgag aatggcacca
     6241 tttcgccgtt ggcgctgcgg acataaagtt tatcgacatc ttctggcagc atacggaatt
     6301 tggcatccgc ctgaacatac acctttttca cgcgaccacg gtcgatgaag tcgttaacgt
     6361 aagtcccacc caacgccgtt gaaatggtct gattgatgtc agaaagtgaa acacctaatg
     6421 cctgcgcctt ttcctggtca acttccagtt taaactgcgc ggtgtcttcc aggccattag
     6481 gacgcacgct gactaagctg gcaggatgtt gcgccgccat gccaagcaac tggttacggg
     6541 cctgggtcag ggcatcgtga cccagcccag cctgatcaat taactcaaag tcgaaacccg
     6601 ttgccgtgcc cagttcaaca atggctggca tattgaatgg aatgacaaaa ccgtcgcgga
     6661 tcttgcccaa ttccattttg gcacgatgga ttaccgcttc cgcactgttt tcatcactat
     6721 tacgctcttc ccacggtttc agactgacga aggccatacc ggcgttttgt gcctggccgc
     6781 tgaagctaaa gccgttaacc gtaaagacac tttcaacgtt cgctttctcg ttcttcagat
     6841 agtaatccgt cacttgatcc aacacttttt gcgtccgctc ttgcgtcgcg ccagcgggta
     6901 actgaatcat ggtcagaaag acaccctgat cctcttcagg taagaaggaa gacggaagac
     6961 gtaaaaacaa caccaccatt cctgcaacaa tcagcgcata gatcagtaaa tatcgtcctg
     7021 tggaaccgag gattttgccg acgctgttgg tgtagtggtt aacgctatga tcgaaggtgg
     7081 tattaaacca gccgaagaaa ccacccttat tttcgtgatg ctcagctgag gtgggtttga
     7141 gcagtgttgc acataacgca ggggtaagaa tcaatgccac cagaacagaa agcgccattg
     7201 ccgaaacgat ggtgatagag aactggcgat aaattgcccc agtagaaccg ccgaagaatg
     7261 ccatcggaat aaataccgct gacagcacca tcgcgatacc caccagtgcg ccctgaattt
     7321 gcgacatcga tttttccgtc gcttcttttg gcgggagctt atcctccatc atcacgcgct
     7381 cgacgttctc caccaccact atcgcatcat cgacgagcag cccgatggca agcaccatcc
     7441 cgaacatcgt tagtgtgttg atggagtaac caaaagcggc gaggatggca aacgtcccta
     7501 ataacaccac gggtaccgca atggtgggga tcagcgttgc tcgcatattc tgcaagaaca
     7561 gatacatcac caggaacacc agcataatgg cttcgaacag cgtttttacc acttcgtgaa
     7621 tagaaagctg gacgaatggc gtggtgtcat aagggtagag aaccttcatt ccctgcggga
     7681 agaatggctg taattccgcc agttttgcct taatggcttt cgcggtatcg agagcattcg
     7741 cgccggttgc cagcttaatc cccaggcccg ccgccggttt tccgttgata cgagcgataa
     7801 cgttatagtt ttcaccgcca agttcaactc gtgcgacatc tttcaggcgt accaccgagc
     7861 cgtcactgtt tacgcgcagg gttactttgc cgaattcttc cggatttttt aaccgcgtct
     7921 gagcaataat tgaggcgttc aactgttgcc ctggtaacgc tggcgttccg cccaactgtc
     7981 cggcagcgat ctgatcgttc tgtaccttca actggttaat cacatcaacc ggtgtcagtt
     8041 tatatttgtt tagcagatcg gcgtccagcc agatacgcat cgcatactgt gcgccgaaaa
     8101 gctgtacgtc accgacgcca ttcagacggc taagcgtatc tttaacgtta gaggccacat
     8161 agtccgagat atcgtcctgt gtggtgtctg ggttatcaga gacaaagccc gccaccatca
     8221 aatagctgct actggacttt tcaacactga tcccctgctg ctgaacctcc tgcggcagca
     8281 acggcgtggc gagctggagt ttgttctgca cctgcacttg cgcgatatca ggatcggtcc
     8341 cggactggaa ggtaagggta attgtcacgc taccggcgga atcgctggtg gaggacatat
     8401 acatcaggtt atcgataccg ttcatattct gttcgataac ctgcgtcacc gtatcctgca
     8461 cggtctgcgc atcagcgccc ggatagtttg ctgaaacaga aaccgcaggc ggtgcaatgg
     8521 ttggatactg agcgacgggt aattgtagat cgccagtgcg cccgccatca tcagaataat
     8581 ggccagcacc catgcaaata tcggtcgtcg aataaaaaag tttgccatgt cagattacct
     8641 tacttcgatg cagtatctgc gggggtatcg gtagtggctt taacctgctc tcccggacgc
     8701 gctttttgca ggccgctgac aatgacttga tcgccagatt tcagaccttc gctaatcaac
     8761 catttatcgc caatcgcctg actggcaacg acagggcgcg cttccacctg acttttatcg
     8821 ttaacaatca gcacggttgc atcaccacgc ggtgtgcggc taacgccttg ttgcgggata
     8881 agaatggcgt caggttggac gccttcatca atccgtgcgc gcacaaacat acccggcaaa
     8941 agcgtatgtt gcgggttagg gaagacggca cgtagggtta tggagccggt gctttcatca
     9001 acggtcacat cagagaattg cagcgtacct ttcaggggat aggtttgacc gttttccatg
     9061 accaactcta cgttgctggt ggcgttttcc ttatgcaaat ttccttgctc tacggattgc
     9121 ttcagcctca taaaatcgtt gctggattgg gtcacatcaa cgtagatagg atcgagctgc
     9181 tggacagtcg ccagttcagt cgtttgccca ttagtgacaa gagcgccttc ggtcacggtc
     9241 gatttgccga tacgtccgct aattggcgca gtcactttgg tataagcgag attgatgcga
     9301 gcgctttcga ctgtggcttt tgcggcaatc acggcggcat cggcctggcg agcatcagca
     9361 atggcctggt cgtactcctg ctggctgatg tatttcgtac ccacgagcgg aacgtaacgt
     9421 tttaccgtca aatgcgcgat ggcggcggcg gcttcacttt tcgccagttc gcctttcgcg
     9481 ctgtcataat ttgcctgata ggtcgcggga tcgatctggt acagggactg gcctgcttgt
     9541 acatcgctgc cttcagtgaa attacgattc agtacgatcc cgctaacctg tgggcgaact
     9601 tcggctatac ggtaagcatt ggtgcggcct ggtaattcag tcttaacttc taacggggcc
     9661 gttttcacaa tatgaacggt aacctgcggt tcaccgacgt gagctttctc ttctccctta
     9721 tcgttacaac cggcgattaa agccgcggag atcagaataa aggagggcag gaggaaaaac
     9781 ctggcatgtt tcgtcattac tattcctcaa aaaaccaaaa gcgcgttatt tacccagaaa
     9841 ggcaacgcgt taactcgcag aaagaaaaat acagtttgct atcctacaaa ttatcattcg
     9901 tcgatgtaag gaatagttat gaatactggc gtctcaaggc acataaacac aaaaaaagat
     9961 taatattcta ctgttttatt ttgacgcggg ttgaaagagg cagaattaaa acctcgtaaa
    10021 ttgaaatata tattcatgtg gcgaatgtat tttaggtaaa taatatatat tatttatttg
    10081 acgatttata gcaactcaat attagcctct cgtataaata cacattaggt gatagattaa
    10141 ccttcgctat tttctcactc tgtgtcgaat atatttattt cctgaataat taatcatggc
    10201 aaaaagaacc aaagccgaag ctctgaagac ccggcaagaa ctgattgaaa ctgccatcgc
    10261 ccagtttgcg cagcatggcg taagcaagac gacactcaac gacattgccg acgctgctaa
    10321 cgttacgcgt ggcgctatct actggcactt cgaaaacaag actcaactgt ttaatgagat
    10381 gtggttgcaa cagccttcat tgcgggagtt aatccaggaa cacttgacgg ctggattaga
    10441 gcatgacccg tttcaacaat tgcgtgaaaa attgattgtc ggcttgcaat atattgccaa
    10501 aattccccgc cagcaggcgt tgctgaaaat cttatatcac aaatgtgaat ttaatgatga
    10561 gatgctggcc gagggagtga tacgcgaaaa gatgggcttc aatccgcaga ctctccgcga
    10621 agtattgcag gcgtgtcagc aacaaggttg tgtagcaaat aacctcgatt tagatgttgt
    10681 gatgattatt attaatggtg ccttcagcgg aattgttcaa aactggttaa tgaatatggc
    10741 gggttatgat ctttataaac aagcccccgc tctggtcgat aacgtattaa gaatgttcat
    10801 gccagatgaa aacataacga aattaattca tcaaacgaat gaattaagtg tcatgtaaat
    10861 tcacattctg tcctgaaaat tcagttcgtc acagttaacc agttttagtg gattaactga
    10921 gttcatattg cggcatttgt ctgtttctgt tgccagcagt tcaatccact gcatcagtaa
    10981 agtatcaaac agaaaaacga agacagcgaa aacgacgagc caccaatact tgcgaatcat
    11041 tacctgagcc tgtgtatgtt taaccaagtc tggcaggaaa tatacacgaa atgaataatc
    11101 tgaaaaccag gcttacactt cctttacttt gcaatgagat cggggtcaac ttcgcttaac
    11161 cggcttcgtt ttgacaggtt gccggtcttt ctttttttca ctttcgccag ttcttccgca
    11221 gagtaatgcg acgcgacatc cagccgtcga agccccattt tgatgtactc gctgttgatc
    11281 tcaataccaa tgaattttcg cccgctggag acggctacgg caccggtagt aaagctaccg
    11341 gcaaacgggt cgagaacgat atcgcctggg ttggaagagg cgagaataat gcgtttcagt
    11401 aaggcttccg gtttttgcgt cgggtggttc tcatattcat ccatcaaata acgcacgcgc
    11461 ggaaaatccc agacgttacc cggtactttt tgatgattgt atggctgtgg aggatttttg
    11521 cgataatcga tcaacgcgcg ctgcgatccg gttttggctt ctaccagaat agcatcaccg
    11581 ttgaatgtgt agttctttgc gtctttcacc atcatcagga tgggttcgta catggagccg
    11641 tagtgttttt tcgcctgtac tccagaactg tcatatgacc agacgatgcg acttttgatg
    11701 gtaaaaagct tgcggcactg gagatcgata aagggcatgt tttccgtgct gttcatgatg
    11761 tacatgctgc cctgcttttt cagaacgcgg tggcactctg caatcacttc aaacagccag
    11821 tcgataaaca gatcttcttt ccaggcttcg atcagaccat caaaattttt accgatgtta
    11881 tatggtgggt cggcaaagat cagatcgaca ctttcggcgg ggatcttttt aagttcggca
    11941 agcgcatcac cgtgaataat ggtcttagct tcattaccaa accgggtcgg ttcacatcct
    12001 gttctcatgg tcactccctt tgtgacacct ataaaaaagg cgcttcccca tgccgagtag
    12061 cgccttttta atcaagcatt tagctaacct gaattagttc atgccgtatt ataggtgtgc
    12121 ttatcatcat aaatcacttt gaaacatcgt gagtaattta aagtaattcc aatctattga
    12181 tttttagatg tttattttta ttgctttcgt tcgtattgtt tcagtttgtt ttaatggtta
    12241 tcatgcattt agtgtaacta ttggtgtaac tattatggcc aatgacaaat tatcagacat
    12301 gaaactgcgc gccttaatgc gggctgatgt cacaaaaccg aaaaccatcg ctgatggtgc
    12361 aggtctgtcc atacgtgtga ccccttcaca gaaacagact ggcaatgatg acaagcgacc
    12421 gactaataac cttttatggc tattccgtta caggaaccct cataaaagca ctaacccatt
    12481 aacacttgtg ctgggccgct accctgattt gtcgttatct gccgcacgtg cacagagaga
    12541 caaatgtaag tcttggcttg ctgacaatct tgacccgaaa gatcaataca aacttacatc
    12601 gacagaaaca ttgaatcccg tgacagtaag gcaggctttg cagtactggg tagacaacta
    12661 tgctgttcat aaccgggcaa actatcaaag gcaccaggcg caattggata agcacatttt
    12721 tccctatata ggggatatgc ctttatcact atgcgaaacc aaacattggc tttcatgctt
    12781 tgatagaact aagaaaaaat ctccggtggc tgctggttac attttccaga tgtgcaagca
    12841 ggcccttaaa tattgccgag ttcgtcggta tgcgttcagc aatgctctgg atgatttggc
    12901 tattcctgat gtagggcaaa agcaagctaa aagggaccgt gtgcatagcg aagctgaact
    12961 ggcagacata tgtaatgcaa taacgtctga aacctttttt ctcccctatt acaatgcatt
    13021 gctaaaaata ttactggtct ttggcgctag aaccaatgag gtccgcctgt ctgaaactaa
    13081 ggaatgggat gttaaaacgt gggtttggac agtacccaaa gaacacgcca aaggcggcga
    13141 aaagattgtg cgtcccgtac ctgaagccat aaggccgttt atcttagacc tgattgagca
    13201 acataaagat actggcctgt tactcggtga gttgaagaac cccgaagctg tcagtcagtg
    13261 gggaagaagt atctacaaac gtctgggaca ttcagaaccg tggacgcttc acgatcttcg
    13321 ccgtacgttt tctaccacgc ttaatgatat gggggttgcg ccgcatattg tagaggggct
    13381 gttaggacat gcgcttggcg gtgtcatggc aatttacaat cggagtcagt atctgcccga
    13441 aaagttagac gccctaaata aatgggttga taaactttca gatttacaaa aaattacaaa
    13501 ttgattgtgg ctagataaaa caagcagtta gcggtggtgg tatttacctt tgtaaataaa
    13561 catttaagta gttaaatgct tgttttacct aggtaaattg catggtgaaa caataagtat
    13621 tatcttgaat ctgtgcttat cgagacgcac aaaaaagagc ccccagcagt accgagggct
    13681 ctgaaaagag tggggccgat tacaagtttt cgcggactga atcgaccccg aataccaaaa
    13741 aagccagtgg aatggctgca atggttgcgt tggttcataa cgcagtatca ctatatatca
    13801 ttgcatacca tatttccacc ggccctgttt gagggcagta aaatggaaat gttaacaaca
    13861 aagcaagtct gcgcattaac tactcttagc cgtgtgacca tttggcgcta tgaagtgtca
    13921 ggaatgtttc ctgcacgtgt tcagttaggt ccaaaaagag tggcgtggca taaggccgaa
    13981 gtagaggcct ggatgaaaag ccgccagcca gtacagcgct gaggtggctt atgaaacaag
    14041 tcaccactgc cgaagcaatc cgtaattata acggcctgtt gcgtaatccc ttacgccagt
    14101 taactgttgg cgaactcacc gcccagcgca tggcggctgc acaatcattg ttgcaagcgt
    14161 gcatccgcga aggtgtaaac cgcccgtgga ctattgtttc acgtcatgcc gctatggctg
    14221 atagcctggt gccgttccgt atcagcgatt ctgaatcatg ggcgatgtat ctggagttaa
    14281 aacgcggggt gcgaaatgag aaacgcgcct aacgttaagc tgttaccgaa agaccctttt
    14341 acggaagcca ttatttttgc cggttctgac gcctggagtc atgccaaggg ctgggaagaa
    14401 ggcatgggta aacaagttgc cggtgacacc actccgcccg tctatcttgg gccaagacaa
    14461 ctggctgatt tagataatct acgaattatc gacgatggtc gccggtctgc tcgggtatat
    14521 ctggccggtg atattgagca acttcaaatc agcactattg ctgacaagct ggcagtggct
    14581 ggagttaagg aagcccgttt atttaaaggt ataccagacc gcgaaccgga aaaatggaac
    14641 atggacaggc ttagagacgc cgccctacgc ggtgaaagcc tggtgggtat gctgcgcaaa
    14701 gaagaacgag caaccgccgc agcaactgca aaagacattc acgatatgac gcctgtatta
    14761 atgacaacct ggccaaatat tggaagcaat ggccagcctt taaacacgcg ccccaatgtt
    14821 gaacgtctat tagataacta cagcatttct gcaaaatata atgagattag caaggacgtt
    14881 gaggttttag tgcctggcgt tagtagcggt tcagatgctc gcgataactg cgctgtgagt
    14941 gaaattttaa gtctcgccgc actgaaccgg ttaccaatga gcaatattga aggtcatatc
    15001 aaaaccatcg ctgtgcgcaa tacttataat cctgtcaggg atttcatcaa tcagcgtgaa
    15061 tgggatggcc ggagccgatt tgcagaccta ctgaatacca tcagcacgcc agatgactac
    15121 agccgtgatc tgctggccat gctggtgcgt cgttggttgc tgtctgccgt ggcggctgct
    15181 tacttagaag cgggtttctg gtccaaaggc gtgctggttt tccagggcga gcagtcgctg
    15241 gggaaaacag catggtttaa agcgcttctg ccccctgaca atcgcaacct ggttaaggtg
    15301 ggagcaacta ttgaccctag caataaagac agcgtggcca gcgcaattag tcactggctt
    15361 gttgagctag gtgaactgga tgcgacgttc cgcaaggcgg atattgccaa gctcaaagca
    15421 tttatcagtc aggaccgtga tgacctgcgc cgcccttatg accggcttga atcgaagtac
    15481 cagcgccgca ctgtgttttt tgcatcggtc aaccccaaac acttccttgc tgacgatacc
    15541 gggaacgtgc gctggtggac tatccctgtg actgccgtta actacgagca tggcatagac
    15601 acacaacaat tatgggccga agttctttcc tggtttgagg caggtgaacg ctggtggctg
    15661 gatcgtgatg aagaagccat gctggaagta gtgaacgaac agcacgggca aactgacccg
    15721 attgaagaaa tgatattggc gcgttttgat tggaacagtg atcgcctggc tgcatatata
    15781 gaaatgactg caacggatgt tctgttgtct attgggcagg atcggccaac aaaatcccag
    15841 gcaacgcagt gcggtaacat tctgcgaaaa ctgactggaa gggatgcacg tagaacaagt
    15901 aaagggcgtt tttacctaat gccaccgaaa gtttttggac agcaagacca tagctatttt
    15961 gatgggccta accgacagtt ttgaggtgat actatgagtt atcgcgtata tatcattgct
    16021 tttgacccgg aacacggcac ctacaccgaa accgaaatca tggaaggttt cgccactgaa
    16081 caggaagcgg tagaccatgc tcgcaatagg ctgccagagg tgcagcagga actggccaag
    16141 ttgggtgaaa acctgctatg cagctaccgc ataagggtag tggattccgc tgaaatcttg
    16201 ccgtttctcc gctcataaca tcacaacagt tgttgcccat tgccctggcg aatgccgggg
    16261 ctttttttat ttccaaggtg acgcctaggt gtcattaatt tataaggtgt catggtaggt
    16321 gtcattgttc tcaagcccta acctgcaagg gttgcggcat tactaatgac acctatgaca
    16381 cctatgacac ctatgacagc atttttaaag aaaataacga ccactgtaat aatgtaacag
    16441 tggtcgttct actttataga aatgggtgtc atggtgtcac aggtgtcatt cattacagtg
    16501 tcttgtttgt atttttcttt aataatcagc gtgtttcccg ctatgacacc taatgacacc
    16561 tttccaacat aacgccgtca tggtgtcata ggtgtcatcg ccatctgctg ccaaaaaatg
    16621 ccgggtcctt cctggcggcc accccatgcg ggggcatatc acccgcatta ttcgacatct
    16681 gcgtgccatt ccaaaatcgt ttttatgatt atttcaggta aatcaagaat ttacatgatg
    16741 actatcaacg ccatgcagtg aaaccgtgtt atttacattg caaagcgaac acatatcaag
    16801 ggtaggaata atcctaaaat atcgtgattt ccgttagctg tagttatcca tagttattca
    16861 gcgtgtttca caatgataag tggctgattt tacttctaaa tttacacttt gtggccattg
    16921 tgttcggcga tcttcctggt attctctcaa taaatcctga gtaattgaga gaaccaaaat
    16981 gaatgacgta ctttctggac ttattcgcgc agccctggaa catcaaggcg ctcatcttcg
    17041 ctttgacggt aacggcgata tcaatcaagt tatcccggta gagcctgccg cagttcgcta
    17101 cctgtcactg aacgaagtgc tgacgccgaa agccggtagc cagaccacat tcaacggcat
    17161 cattgccgcg cgttccctgg tggccgctgc tggtgctgaa atcatccgca tccctggccc
    17221 catgacgcag caagctgata tcgacgacga aggcaaccgc cgcccgctga aacagcagga
    17281 agtgccgcgc cactacatcg ttgtagcgcc tggcaagttc gcagcagtgg ccgatgacgc
    17341 cgaaatcacc ctgagtgatg ccccttacct agtggccagc tatgacgacg ccacagcgcc
    17401 atcctacggc atcggctaca ccctgacgcg ccagcaactg aaacacacct ttgctgaccc
    17461 tgacaccgtg ctgcgtgccg tcaacagcgc tatcgagcag ggcattgccc gcctggctga
    17521 cagcgttcta ctgactgacc tgaacaccaa agccgcgaca ctgaccgacg ccaccgttga
    17581 tgctgttgca aaggctgccg ccgctaaggg ctgccgctgg gctgacctgt cagccatcgc
    17641 cggaaccagt gctgctggcg tgaccctggg cggtgacgga accctgcgcg cctgtgcggt
    17701 taaagccgaa ctgaccgaca ccattgcaac aaccattgtt ggcgatttta gccgtgcagc
    17761 cgtggcgatt gatgacgaac tgcgcgtaac agccaagcgc atcaacaacg gtgccgttga
    17821 gatcgtcgtg tggtgcaacg cacaggcgtt ggttccagat tctgcgtact tctggaaata
    17881 cggagcttaa tcatgggctg gggcatcaag aaagtggcgg cggaacgcgc cgccttatcg
    17941 ggcgaagtgc tggccgccat tgagggtgcc gccatgtaca cgcgacacgg cgatgctgaa
    18001 gcaccgcgca tcatcgtgca accagcaggc tacaccggct ttatctacag cgaagaagcg
    18061 gcggaaaagt gggtcaggcg cgcgtttatc gaattgacac cgtaccaggt ggaacgcgca
    18121 gtcaattatc tcgcctccct ggtgcgggaa caccaccggg agcatcagcc aaagcgccag
    18181 cgcaatagct gggtgaacag gtggtgatta tgagcaaaga aaacgcagca cgtcagcatg
    18241 tgactgttcg tctggcacct gaactggtgc gccaggtgga acgtgaaaga acaaaactgg
    18301 agcgcagaac aggcatccgt ccttcacgta gccaggtaat tgaaaagttt ctgagtagcg
    18361 ggctgaacgg caaataatgg ccaagaatac aggcttcacc ggttccctgt gccccaaata
    18421 accggcctga tttaatcatt catcgctcct cgggtgatgg gtgctggacc aggttggtgg
    18481 ttatcctgga cggtaaaaac cacacaagaa tccttgctgg ttgcgccgca ccgggaccat
    18541 gaaagcggcg cattcattct tacatcaaca accattgtta gcggccaata ctatgaaaaa
    18601 tcatgacctg tacgaatcaa tgaaggaaga agcgcgttta atccttagcg aaaccaaacg
    18661 ctttcagacc atttcagaga aaaatcctat cagctacgaa gcagccgacc tgctggcaag
    18721 ccttcgcaac cgtttaaacg cattcgaaaa catgaccgat gaagcgggcc gcatcatgcg
    18781 tgacgaagcg gaaagcaacg catccaccct ggagcgcaag aaatggaagc catccagccg
    18841 catcagttcc ggtgaacgtg ccaagcgcca ggcagtgaag cgaggcgcta tcctggtgcg
    18901 tggtgcataa gaatggcaac caacaataac atttatgacg ccgttctgaa cgttatcggc
    18961 gttgctgaca agatgacgaa caacaacgca agccaactga ccgacgcgca gaaggcagca
    19021 ctgaaaaacc ttagcaacgc gatgaaatcc tggaaaggta tcacgtttgg aatgcgtgac
    19081 atcacagcca gtgacaaacc aattgacagt aaaactgcat aaggggcaac catgctggac
    19141 cgtatccata gaaaaccgga aggaatgaac ccctggcctg aactggtgga tgcggtcctg
    19201 ccaaaagttc tggtgtgcaa tacagcggag gaaatgcagg aacagcgaga ctatcgcacc
    19261 gaatgcgctc tgcaactggc tgctgccgcc ttgcgggctg ctggtgaaca caccctggca
    19321 gaaaatttac ttaattagtt ctttgagagc aaaattatta tggccaataa gaagttgaat
    19381 gccacgatta ccataggagg tgccgtttcc ggcagcctcc gtggtgcgtt tggcacggtg
    19441 aagaaatcca ccgttgagat cggcagcgcc atcactcacc tgtcacgcga acagcgccag
    19501 ttgaatgaag caatgaagcg ctacgggcaa aactccgtga tggttgaccg cctgcgcggg
    19561 cgctatgatg ccattgtggg ccaggtggaa cgcctgcgga aagcgcagga gcgtttaaac
    19621 gcagtcgagc gcgccagcgc ggccaacctg gccaagcgtg ccgagttacg cgggcagatg
    19681 ctggacacgg tggcattagg tgccgcagtg gcggcaccca tcaagattgc tgccgatcgt
    19741 gaaagccacg ccgttggcat cgccaagcag ctacagggcg cacgcgacga agcaggcaag
    19801 ctgacgccgg tattctggca gatgcgcaag gctgtgaccg acctggggca cgaaatccca
    19861 ctggccacta atgacctgta cgatatggcc gccgctggcc tgcgcatggg cgtggcaagc
    19921 aatgacatcc tgggctttac ccggaacacg gccaaactgg ctgccgccct ggagctggac
    19981 cccggcgaaa ctgcggaacg cttcgccaag ctgggcaccg tgtttaaact gagtcaggat
    20041 cagttgatgg gcctgggtga cgccatcaac tacctggacg accagaccac ggccaaaggc
    20101 ggtgaaatca ttgactttat ggcgcgtgtt ggtggttccg ctggcctggt gaagattacc
    20161 gcaggccagg tggcagcaat cggcacggcg ctgattagca tgggtgagac ggcagagact
    20221 gccggaacgt caaccgctgc cctgttcagc aagctggcta tgggtgacaa gaacaccaaa
    20281 gccgcccgcg aagcgttcaa ggaattgggc ctgtcagccg gtcagatgtc caaagccgtc
    20341 caaaaggacg ccattggcgc aatggaaatg ctgtttgacc gcgttcgcaa actgccggaa
    20401 gcgtcacgca ctggcgtgct ggtagacatt tttggacagg aacacgttgg caagattgcc
    20461 aaactggtga ccggcaccaa agagcttgcc agcgccctgg aagccgtcaa cggcgaagcg
    20521 tccaaaggca gcgtacataa ggagttccag aacaccatca gcaccaccaa tgcgcagatg
    20581 gtcttactgt ccaaccgcat ggcagacgtg gccgacaata tcggcaccgt tctgttgccg
    20641 tctgtgaacg acgcagccag cacaatcggc aagttcacaa ctgttgtggc caacttcgcg
    20701 caggaacacc ccggcctgac caaagcggtg gtgggaaccg ctgttgccct gacttccctg
    20761 aaagtggcca ccctggctgg cggctatgcc tttacgttcc tcaagggcgg tgctttgatg
    20821 gttgctaagg gtttggcagg ggcaagggca gaaatggcgc tgacggccac cggagcgcgt
    20881 ttaatgggtg catccgcagc cgtggcacgc ggtggcgtca tcggcctggg gcgcgccctg
    20941 gtgatgaacc ctattggggc cattgccgct ggcatcgctg tggctggcct ggccatctat
    21001 aagaactggg acatggtgaa ggctgccgcc atcgggtttg gccgtgggat gctggaaggc
    21061 ttgcagccgg tatctgacgc catcagcacc gttcgccagg cactgacccc gctggaacct
    21121 gcattcaagg tggtgggtga tgcggttaaa ggcgtgttca actggttcag caacctactg
    21181 gagccaacga agcacaccag tgaccagctt aaatcagcca ccgacgctgg ccagacgttc
    21241 ggcaaggtgg tgggcgaggc cattagtttt gtgctgacgc cgctgacggc actggtggac
    21301 ggctttaagt ggatctccga gaacggcggc aaaatcctga acacggttgg cgcaaccatc
    21361 gacaaggcca aatcctggct gccgtcatgg gctggcggaa ctgatgatga cgcaccgaag
    21421 gcagcaacac cgccggggtt aactccacca ccagcaccgg caatggctaa ccgttccggc
    21481 agcaccagtt acaccaccga acagaccaac catttcacca tccatgcagc acctggcatg
    21541 aatgaagatg cgctggcccg taaagttgcc gaaacgctca aacggcagca ggctgtcaga
    21601 ggccgcagca tgatgactga cggggcatat cagccatagc aaaaccctgt gtaacttggc
    21661 gtgtaatcaa aaagcaaagg ggccaattgg ccccttttaa atcaactgct tacggcttat
    21721 ttttagttca tgccgtattt tttcaatttt ttacgcagcg taccacggtt gatgcccatc
    21781 atcagcgcag cacgggtctg gttaccacgg gtgtattgca tcaccatgtc caacaggggc
    21841 tgttctactt cagccagtac cagctcatag aggtcattca catcctgacc attcagttga
    21901 gcaaaatagt tcttcagtgc ctgtttaacc gagtcacgca ggggtttttg ggttacctga
    21961 tcctgagagt taacggtaga aacggtcagt acgtcagaat ttacgcgttg ttcgaacata
    22021 gttctgtcag ctctttattt ctgtttacgc aaaattttcg aagtatgcct ccaacgcctc
    22081 cagctgttcg ctggcatcct caatggcgtt gaatgtgcgc cgaaactggt catttggagc
    22141 gtgttcctgg agataccagg aaacgtgttt acgtgcaatt cggtaccctt ttgccggacc
    22201 ataaaagtca tgcagttccc gaacgtgcgc gcaaagcaag cgcttaacct ctgccaaagg
    22261 cagcgggggc agcaactccc cagtgtccag ataatgctgg atttcccgaa agatccaggg
    22321 tcttccctga gctgcgcggc ctatcatcag ggcatccgcc cctgtatagt cgagcacagc
    22381 tctggcttta agcgggtcag taatgtcgcc attcgcgata accggaatgg aaactttctg
    22441 cttaactgcc cgaatactgt cgtactcagc ttctccattg aacaaacagg cgcgtgtacg
    22501 gccatgaatg gtcagagcct gaatgccaca gtcttcagcc agttgggcaa tctcttcgca
    22561 gttacggtgt tccggtgccc agccggtgcg aatcttcagg gtaacaggaa cgtccactgc
    22621 attgacgacc tcggtaagga tcgatttaac gacatccggg tactgcaaga gggctgaacc
    22681 tgcgagcttg cgattcactt ttttagccgg gcaacccata ttgatatcaa taatctgggc
    22741 accgctttcc acgttaatac gtgctgcatc tgccatttct ttcggatcgc taccagcaat
    22801 ttgcacggtg cgaataccgg gttcatcaat gtgcaccatc cgtaaacgag atttgtcgct
    22861 ttcccaaacc tgtgggttag aagacatcat ctcggatact gtcaatccgg ctcccatctc
    22921 gtagcacaac gtccgaaaag gtctgtctgt aatgccagcc atgggcgctg cgatcaggcg
    22981 atttctgagc tgatattgtc cgatgcgcat gagttaagaa atgaccatac tgtgactgca
    23041 aggcggcgta tattacgcat tttttgcacg agatgaaagg ccaaactttg accaatcctc
    23101 tgagatggat caaagaattg catttaaaat gagcgtggtg cgataattac tcataaaaat
    23161 catcatatta gaaaatagtg actaaaattt acactcaaag aaatttgagt aagttctcaa
    23221 tttttcttta tgaatgaaaa ttttggcacg caaatttgcg taaataaccg gcaaatttac
    23281 gtgccttttg tgagcttgct cgcacttcgc cccgcgtcac cctacggcga tgcgaaggtt
    23341 aattcttacg accggtaata cggcaccact cttctttttc cacgaccggg tccagtgcga
    23401 agctatcggc ataagcttca caaacgctct ctgcctggct tgccagaata ccggaaaggc
    23461 ccagcaaacc gcctgaaacc ggcaggacgc tgattaacgg tgccagttca cgtaatgggc
    23521 ctgcaaggat gttagcgacc accacgtcgg ctttcatttc ttctggctga tctttcggta
    23581 agtagagttc cagacggtca gaaacgccat tacgttcggc gttgtcgcgg ctggcctgaa
    23641 tcgcctgcgg atcgatatca ataccaatgg cttttgctgc acccagtttc agcgccgcga
    23701 tcgccagaat gccggaacca cagccaaagt cgatgactgt tttaccggtt aaatcgaggc
    23761 tgtcgagcca ttgcaggcac agagaggtgg ttggatgggt acccgtacca aacgccagcc
    23821 ctggatctaa catcacgttg acggcgtttt cgtccggcac atcacgccag ctagggcaga
    23881 tccacagtcg ttcaccaaag cgcatcgggt ggaaattatc catccattcg cgctcccagt
    23941 ctttatcttc tagttgttcg attttatgcg cgaagcctgc gccgagcagc ggatggtttt
    24001 ccagaatcgc caccacgtcg ttcatatcgg tttcagcgtc gaacagacca atcacatcgg
    24061 tgtcgcccca caggcgcgtt tcgcccggca gcggctcaaa tactggcgta tcgtgggtat
    24121 cctgaaaagt gatagaaacg gcacccgctt ccatcagcgc atcgctaaga tcttccgcgt
    24181 tcgcgccggt ggtgttcagt ttcagttgga tccaaggcat ggcaaaactc tttatttatc
    24241 agtagtcaaa acggtagctt gcgggacgga tgtaccgaaa cggtttccga ccaggaaagc
    24301 cagcaaactt agtagtaacg agggcacaat agggtggaag cccaggtact gaatattcag
    24361 cgtcgcgagt acggcataca gcacgccgcc aacgatcatc gcacttagcg cgcctttggc
    24421 gttggcgcgt tcccagtaaa gacccagcac cagcggccac aggaaaacgg cttccagccc
    24481 accgaaggcc agcaaattca gccagatgat catttctggc ggcttccagg cggcaagcag
    24541 cagcaacgcg ccgagaacta acgtaattac cgccgacatc cgcttcagac gcgtctcgtt
    24601 ttgcatttga tccggacgga tattcagata gagatcttta atgatcgtag cggaactttg
    24661 cagcaactgg gcattgatcg tcgacatgat cgcagccata ggtgcagcca ggaagattcc
    24721 ggcagcaaac ggtggcagca cttttaccat taacgtcggg atcaccagat ccggtacggt
    24781 gagatcgggg atcactgcac gacctaacgc tccggccagg tgcataccga acatcaggat
    24841 tgcgactaca atcgtaccga tgatgatccc ccggtgtact gctttgctgt ctttataaga
    24901 gatacagcgc accgcagtat gcggcaggcc aatcacgcca aagcacacca gtacccagaa
    24961 cgacgtcata aaggcaggcg acagaatatc gtcagcgcct tgtggcgtaa ccagttgcgg
    25021 atcgatggtt tgcaaggtct gtactgcgtt gcttaagccg ccagcggcat gtaccacgcc
    25081 aataagcagc acaacggtgc caatcagcat cacaagccct tgcatggtgt cgttcagcac
    25141 gctggcgcga aagccaccaa aggcggtata taacgcaatg ctgataccaa aaatcagcag
    25201 cccggtttca taaggaatac ccgccgcggt ttccagcagg cgcgcaccgc cgataaactg
    25261 cacggtcatc gcaccaacga acgcaaccag caaactcaaa ctcgccagcc acaccagaag
    25321 acgactctgg tagcgggcaa acagcatatc gttcagcgtc actgcattgt agcggcgcgc
    25381 aagaatcgca aacttcttgc cgagaatacc gagtgaaagc cagactgcag gaagctgaat
    25441 catcgccagc aatacccagc ccagcccgta tttataagca gctcctggcc cgccgataaa
    25501 cgaactggca ctgatatagg tcgcggtgag cgtcatcgcc agcacaatac cgcccataga
    25561 gcggctgccg aggaaatact cattaaggaa ggtgccggtg ctccgtttac gcatcgcata
    25621 aacagagata ccgaacacca ccaccagata ggcgaccagc ggtagaatta cttcaagctg
    25681 catcgtcatc ctccagtggg atatcgcgat agataaattt caccatcgcc cagcacagtc
    25741 caataaacag tagcggcgtc aggatgcagg ccatctcaaa ccagcgcgga aagccggtaa
    25801 aaccgggggc aacgccaggt aagtaagcgg ctactaacca aactgccaga tacaaaaggg
    25861 tcagccccag cgcccagcgc gcctctttat gggcctgaac aaaacgagtg tccatttttt
    25921 gtccctgatg ggtgaagaaa gcgaggattg taccttatgg gggttgtcga tccccagtaa
    25981 taaaaaaggc cggaaaatcc ggccttttga cgcttttgca gtcttatttt tcctgaagac
    26041 cgagtttttt ctccagatag tggatgttag tgccaccatg ctggaagttc tcgtcattca
    26101 tgatgcggat ctgcagatca acgttggttt tgataccgtc gatgatcagc tcctgcagcg
    26161 cattcttcat gcgagcaatc gccacgtcac ggttttcacc gtagcaaatc agcttaccga
    26221 tcattgagtc atagtacggc ggtacggtgt agcccgcgta gatatgagac tcccaacgca
    26281 ctccaaaacc gccaggtgcg tggaaacggg tgattttgcc tgggcttggc aggaaggtgt
    26341 tcggatcttc ggcgttgata cgacattcca ccgcatggcc gcgaacgtga acttcttctt
    26401 gcttgatcga cagcggttga ccggcagcga tacgcagctg ttctttgatc aggtcaacgc
    26461 cggtgatcat ttctgtaacc gggtgttcta cctgaatacg ggtgttcatt tcgatgaaat
    26521 agaactcgcc gttttcgaac aggaactcga aagtacctgc accgcgatag ccgatatcaa
    26581 cacacgcttt agcacaacgt tcgccgatgt agcgacgcag ttccggtgta attcccggtg
    26641 ctggtgcttc ttcgaccact ttctggtgac gacgctgcat agagcagtca cgttccgcca
    26701 gatagatagc gttgccctga ccgtcagcca gtacctgaat ctcgacgtgg cgaggatttt
    26761 ccaggtattt ctccatgtaa accatatcgt tattgaatgc ggctttcgct tccgcacggg
    26821 tcatggagat ggattgtgcc agttcagcgt cgccgcgcac tacacgcata ccacgaccgc
    26881 cgccgccgcc ggaggctttg ataatcaccg gataacctat gcgtttagca atggcacggt
    26941 ttttatccat atcgtcgccc agcgggccgt cagaacctgg tacgcaagga acgcccgctt
    27001 ttttcatcgc cgcgattgcc gacactttgt cacccatcag gcgaatagtg tctgctttcg
    27061 ggccaatgaa gataaagccg gagcgttcaa cctgctcggc aaagttggcg ttctcggaga
    27121 ggaagccgta acccggatgg attgctactg cgccggtgat ttcagcggcg cttatgattg
    27181 ccgggatgtt cagataactt tttactgacg gagcagggcc aatacagacc gtttcatctg
    27241 ccagtaatac gtgttttaga tcgcgatccg cgctggagtg cacagcgaca gtcttgatgc
    27301 ccagttcttt acaggcacga agaatacgca atgcaatctc gccgcggttg gcaataacaa
    27361 ttttatccag catgttcgcc tcgttactcg atgacgacca gcggctcgtc aaattctacc
    27421 ggttgtccac tttcgaccag aattgctttc acggtaccgg atttgtccgc ttcgatctgg
    27481 ttcatcattt tcatggcttc aacgatgcac agggtatcgc ccacgttgac tttctgaccc
    27541 acttcgatga acgcttttgc gtccgggctt ggggtgcggt agaaagtacc aaccatcggg
    27601 gagcgtacga tgtgaccact gatttccgct gctgctggcg cttccatgga aggaacggtc
    27661 gccggagcgg ctgcgttaga ttgagctggc tgctgcatca ttggtgcagc gtaagcttgt
    27721 tgcatcacag ggaaacttgc ggcaggagct gcacggctga tgcgtactga ctcttcgcct
    27781 tcggagattt ccagttcgga gatgcctgat tcttcaacca gctcgatcag ttttttaatc
    27841 ttacgaatat ccatgagtgg gttccgtact ctttgtttag tgtgattgtg acaggcgttt
    27901 caccgccgtc tgtaaagcgt atgccccgac agctgtatgc atagcgataa attccagcag
    27961 gccgggacgc cggtctattt tgccccagag tgtcaatgtt agacttgacg gacattgtgc
    28021 agcgatctgc tgctatcctc cggcaaaaaa caaaatatac cttcgttgcg ccaatgtcac
    28081 cttttccgca gcgcaaaaac tgtgtcaggg aggacgaggt cgcacattat aacgatttcg
    28141 tagcaattgg cagctaaata ctggtcttat cagggaagat aatcaacagc taacatgtaa
    28201 ataaccttca acaccgtgta atttgcaaca agccgcacaa ttcacgaaat tagcgccatc
    28261 atcgacggaa cttcttataa cgtaaggtga aaagctgtaa agccagccct gcgaagatga
    28321 ggggctgcaa tgagataatc ttcacagacc acaaataatg tagggatgcc aggatcgcga
    28381 caagatagac gacattacgc agcggttgct ggggattacc caattttcac tgcatcgtct
    28441 ggatagatgt gaatgctaaa gcacgcaaaa tcaaccgact gacaattctc agcattaaat
    28501 aggttcgagt ggttaatttg tagtcaaata aaatcagatt attcacccca tgggaccaga
    28561 aatcagtaat aggttaagcg tagtgtcgcc caggcaaagc accataaacc taacaggcga
    28621 cggaggcata tcaataatgg ctgtttagag gagtatcaat gcgcatcaat ttgtggtcag
    28681 tcgaaatcat gactttccag tttggatgat gttgtacaac ttcctgacca aggtgttcga
    28741 cgaaagctgt ccggctaacc gcttttcccg ttaaccgatt gaataatgat gtcaaaatga
    28801 gttccctctc ttattattcc ttgctaaatg gttagttaac cttcaccagc gtgcgaccct
    28861 ggatctggtt attaatgatg gcctcggcaa agttcggtgc ctctgacaga gatatctctt
    28921 ttgccgcctg ggtatagaat gattccggta aatcggcgac cagtcgctgc caggcttgtg
    28981 cgcggcgttc tggtggcgtc attactgaat ccaccccttg caaacggaca ttacgcagaa
    29041 taaatggcat gaccgtggtt ggcagagtaa aaccacccgc cagaccacag gccgccacgc
    29101 agccgccgta attcatttgc gccagcactt ttgccagcac tttgtcgcca acagtgtcaa
    29161 ttgccccagc ccagacttgt ttttccagag gacgggattc ggcaaactca tcacgaggga
    29221 gaatacgact ggcacctaaa cttttcaggt attcatgggt actttcgcga ccggaaacgg
    29281 caacgacctg ataacccaac ttatgcagca gcgccacggc ggtactgccg acgccaccac
    29341 tggcacccgt cacgacaatc tccccgtcct gcgggcgaac accggcatct tccagcgcca
    29401 tcacacacag catggcggta aaaccggcag taccgataat cattgcttta cgcgcgtcca
    29461 gcccttgcgg catggcaacc agccagtcac ctttcactcg cgcctgctcc gccagcccac
    29521 cccagtggtt ttcaccaacg ccccagccag tgagtaacac ctcctgaccg gcatgaaaac
    29581 gcggatcttc gctggtgcgt acagttccgg caaaatcgat cccaggaatc atcggaaaat
    29641 tacggatgat ttttccctta ccggtaatcg ccagcgcatc tttatagttc aggctcgacc
    29701 agtgaacatc aaccgtgaca tcgccctccg gcaggcgact ttcgtcaagt gtctgtaccg
    29761 atgcgagagt tttgccgtcc tgctgttcta aaagtaacgc ctgcataagt ggtcctcatg
    29821 tgcatgatgg attggaaaat aatttctgaa gactatactc gctaatggaa aagcaaagcc
    29881 gatgaagcgc aataaattgc gagataaatc tgatttgcta gtatgcccgc ttcctcacta
    29941 tcggagttaa cacaaggatg agattaacga cgaaattttc ggcctttgtt acgctgctca
    30001 ccgggttaac aatttttgtg actttgctgg gctgttcgct aagtttctac aacgcaattc
    30061 agtataagtt tagtcatcgc gttcaggcgg tggcgacggc gattgatacc caccttgtgt
    30121 cgaatgactt cagcacatta aggccacaaa ttaccgaatt aatgatgtcg gcagatatcg
    30181 ttcgtgtaga cctgctccat ggtgataaac aggtttatac cctggccaga aatggtagtt
    30241 atcgtccggt tggctccagc gatctgtttc gcgaactgag tgttccgttg ataaagcatc
    30301 cggggatgtc gctgcgtctg gtttatcagg atccgatggg caactatttc cattctttaa
    30361 tgactaccgc gccgctcacg ggggcgattg gctttatcat tgttatgctc ttcctggcgg
    30421 tacgctggtt acaacggcaa cttgccgggc aagaattgct ggaaacccgg gctactcgta
    30481 tcttaaacgg tgagcgtggc tctaatgtgt tgggaaccat ctatgaatgg ccgcccagaa
    30541 ccagcagtgc gctagatacg ctgcttcgtg aaattcagaa cgcacgcgaa caacacagcc
    30601 gtcttgatac gctgatccgc tcttatgccg cccaggacgt gaaaaccggc ctcaataacc
    30661 gactcttttt cgataatcag ttagcaacgt tactggaaga tcaggagaaa gtaggtaccc
    30721 acgggatcgt gatgatgatt cgtctgccgg atttcaatat gttgagcgat acctgggggc
    30781 acagccaggt tgaagaacag ttcttcactc tgacgaatct gctgtcgaca tttatgatgc
    30841 gctaccctgg cgcactgctg gcgcgttacc accgcagtga ttttgctgcg ctgttaccgc
    30901 accggacgtt aaaagaggca gagagcatcg ccggtcagtt aatcaaagcc gtcgatacct
    30961 tgccgaacaa taaaatgctc gatcgcgacg atatgatcca cattggtatc tgcgcctggc
    31021 gtagtggtca ggataccgag caggtaatgg aacatgcaga gtctgccacg cgtaatgcgg
    31081 gattgcaggg cggcaatagc tgggctattt acgatgactc gttgcctgaa aaaggacgcg
    31141 gtaatgttcg ctggcgtacg cttatcgagc aaatgctcag tcgcggcggc ccgcgccttt
    31201 atcaaaaacc ggcggttact cgcgaaggtc aggttcatca tcgcgaactc atgtgccgca
    31261 tcttcgatgg taatgaagag gttagctcgg cggagtatat gccgatggtc ttgcagtttg
    31321 gcttatcgga agagtatgac cgtctgcaaa tcagccgtct tattccacta ttgcgttact
    31381 ggccagagga aaatctggcg attcaggtta ccgttgagtc gctgattcgc ccgcgttttc
    31441 agcgttggct gcgcgatacg ttaatgcaat gtgaaaaatc acaacgaaaa cgcataatta
    31501 ttgaacttgc agaggccgat gtaggtcaac atatcagtcg tttacaacct gttattcgtt
    31561 tagtgaatgc tttaggggta cgggtagccg tcaaccaggc tggtttgacg ctggtaagca
    31621 ccagttggat caaagaactt aatgttgagt tactcaagct ccatccgggg ctggtcagaa
    31681 acattgagaa gcgaacggag aaccagctgc tggttcaaag cctggtggaa gcctgctccg
    31741 ggaccagcac ccaagtttac gccaccggtg tgcgttcgcg aagcgagtgg cagaccctga
    31801 ttcagcgcgg tgttacaggc gggcaagggg attttttcgc gtcctcacag ccacttgata
    31861 ctaacgtgaa aaaatattca caaagatact cggtttaacc tgccgtttaa tctgttttca
    31921 cgtagaataa cgcgcgctgc gtctcatggg agtgtgcttg tctgctcgcc agattgttgc
    31981 agcacatatg cagatgaatg accttacgcg gttgcaaaca ggcgaggaat gctgctgatg
    32041 cattaagcct ttctggactc aggcagagat ttgtaacaaa ggaaacgaac tgcactaatt
    32101 ttcaccgtag cagatgattt ttgcgccttg tcgctgctgc gtgtggttgg taaagtaagc
    32161 ggattttctt ttccgcccca gctttcagga ttatccctta gtatgttgaa aaaatttcgt
    32221 ggcatgtttt ccaatgactt gtccattgac ctgggtactg cgaataccct catttatgta
    32281 aaaggacaag gcatcgtatt gaatgagcct tccgtggtgg ccattcgtca ggatcgtgcc
    32341 ggttcaccga aaagcgtagc tgcagtaggt catgacgcga agcagatgct gggccgtacg
    32401 ccgggcaata ttgctgccat tcgcccaatg aaagacggcg ttatcgccga cttcttcgtg
    32461 actgaaaaaa tgctccagca cttcatcaaa caagtgcaca gcaacagctt tatgcgtcca
    32521 agcccgcgcg ttctggtttg tgtaccggtt ggcgcgaccc aggttgaacg ccgcgcaatt
    32581 cgtgaatccg cgcagggcgc tggtgcccgt gaagtcttcc tgattgaaga accgatggct
    32641 gccgcaattg gtgctggcct gccggtttct gaagcgaccg gttctatggt ggttgatatc
    32701 ggtggtggta ccactgaagt tgctgttatc tccttgaacg gcgtggttta ctcctcttcc
    32761 gtgcgcattg gtggtgatcg tttcgacgaa gctatcatca actatgtgcg tcgtaattac
    32821 ggttctctga tcggtgaagc caccgcagaa cgtatcaagc acgaaatcgg ttcggcttac
    32881 ccgggcgatg aagtccgtga aatcgaagtt cgtggccgta acctggcaga aggtgttcca
    32941 cgcggtttta ccctgaactc caacgaaatc ctcgaagcac tgcaggaacc gctgaccggt
    33001 attgtgagcg cggtaatggt tgcactggaa cagtgcccgc cggaactggc ttccgacatc
    33061 tccgagcgcg gcatggtgct caccggtggt ggcgcactgc tgcgtaacct tgaccgtttg
    33121 ttaatggaag aaaccggcat tccagtcgtt gttgctgaag acccgctgac ctgtgtggcg
    33181 cgcggtggcg gcaaagcgct ggaaatgatc gacatgcacg gcggcgacct gttcagcgaa
    33241 gagtaatcgg atgcaggcag gggaaatgtc tgtttaccct gcctggtctg atacgagaat
    33301 acgcataact tatgaagcca atttttagcc gtggcccgtc gctacagatt cgccttattc
    33361 tggcggtgct ggtggcgctc ggcattatta ttgccgacag ccgcctgggg acgttcagtc
    33421 aaatccgtac ttatatggat accgccgtca gtcctttcta ctttgtttcc aatgctcctc
    33481 gtgaattgct ggatggcgta tcgcagacgc tggcctcgcg tgaccaacta gaacttgaaa
    33541 accgggcgtt acgtcaggaa ctgttgctga aaaacagtga actgctgatg cttggacaat
    33601 acaaacagga gaacgcgcgt ctgcgcgagc tgctgggttc cccgctgcgt caggatgagc
    33661 agaaaatggt gactcaggtt atctccacgg ttaacgatcc ttatagcgat caagttgtta
    33721 tcgataaagg tagcgttaat ggcgtttatg aaggccagcc ggtcatcagc gacaaaggtg
    33781 ttgttggtca ggtggtggcc gtcgctaaac tgaccagtcg cgtgctgctg atttgtgatg
    33841 cgacccacgc gctgccaatc caggtgctgc gcaacgatat ccgcgtaatt gcagccggta
    33901 acggttgtac ggatgatttg cagcttgagc atctgccagc gaatacggat attcgtgttg
    33961 gtgatgtgct ggtgacctcc ggtctgggtg gtcgtttccc ggaaggctat ccggtcgcgg
    34021 ttgtctcttc cgtaaaactc gatacccagc gcgcttatac tgtgattcag gcgcgtccga
    34081 ctgcaggact gcaacgtttg cgttatctgc tgctgctgtg gggcgcggat cgtaacggcg
    34141 ctaacccgat gacgccggaa gaggtgcatc gtgttgctaa tgaacgtctg atgcagatga
    34201 tgccgcaggt attgccttcg ccagacgcga tggggccaaa gttacctgaa ccggcaacgg
    34261 ggatcgctca gccgactccg cagcaaccga cgacaggaaa tgcagctact gcgcctgctg
    34321 cgcccacaca gcctgctgct aatcgctctc cacaaagggc tacgccgccg caaagtggtg
    34381 ctcaaccgcc tgcgcgtgcg ccgggagggc aatagtggcg agctatcgta gccagggacg
    34441 ttgggtaatc tggctctctt tcctcattgc gctgttgctg caaatcatgc cctggccgga
    34501 taacctgatt gttttccggc caaactgggt gttactcatc ttgttgtatt ggatcctggc
    34561 cttgcctcat cgcgtaaatg tgggcacagg ttttgtgatg ggtgccatac tggatctgat
    34621 cagcggctcg acgcttggcg tacgcgtatt ggcgatgagc atcattgctt acctggtggc
    34681 gctgaaatac cagcttttcc gcaacctcgc attatggcag caggcgctgg tcgtcatgtt
    34741 gctttcgctg gtggtggata ttattgtttt ctgggcagag tttttagtga ttaacgtctc
    34801 tttcagaccg gaagtgttct ggagtagtgt agtcaatggg gtgctctggc cgtggatttt
    34861 cttgctgatg cgtaaagtcc gtcagcagtt tgcagtgcaa taaaggtttc tatgacttct
    34921 ctgtatttag cttccggttc tccgcgtcgt caggagttac ttgcgcaact tggcgtgacc
    34981 tttgaacgta ttgttacagg cattgaggag cagcgtcagc cgcaggagag cgcgcagcag
    35041 tatgttgtgc gtctggcgcg cgagaaagca caggcgggtg tcgcgcaaac ggcgcaggat
    35101 ctcccggtgc tgggtgcgga tactatcgtt atcctgaatg gagaagtgct ggagaaaccg
    35161 cgcgacgcag agcatgcggc gcagatgttg cgcaaattat cgggtcagac ccatcaggtg
    35221 atgacggcag tggcgttggc cgacagccag cacattctcg attgcctggt ggtcaccgat
    35281 gtgactttca gaacgttaac agacgaagac atcgcgggct atgtcgccag cggtgaaccg
    35341 ttagataaag caggtgcata cggtattcag gggctgggtg gctgttttgt caggaagata
    35401 aatggcagct atcacgccgt agtcggctta ccgctggttg aaacgtatga attattaagt
    35461 aattttaacg cactgcgtga gaaaagggat aaacatgacg gctgaattgt tagtaaacgt
    35521 aacgccttcg gaaacgcgag tggcgtatat tgatggcggt attctgcagg aaattcatat
    35581 tgaacgtgag gcgcgacgcg gaatagtagg caatatctac aagggtcgtg taagtcgtgt
    35641 acttccgggt atgcaggcgg cttttgtaga tattgggctg gataaagccg cgtttcttca
    35701 tgcatccgat atcatgccgc acaccgaatg tgtggcgggt gaagaacaaa agcaattcac
    35761 ggtgcgcgac atctcggaac tggttcgtca ggggcaagat ctgatggtgc aggtggtgaa
    35821 agatccgctt ggcactaaag gtgcgcgcct gaccaccgat atcacgctgc cttctcgcta
    35881 tctggtgttt atgccagggg cttctcacgt tggggtttcc caacgtattg aaagcgaatc
    35941 agaacgtgaa cgcctgaaaa aagtggtcgc agagtattgc gacgagcagg gcgggtttat
    36001 catccgtacc gcagcggaag gggttggcga ggctgaactg gcctccgatg ccgcttatct
    36061 gaaacgcgtc tggaccaaag ttatggagcg taaaaaacgc ccgcagaccc gttatcagct
    36121 gtacggcgaa ctggcgctgg cgcagcgtgt tctgcgtgat ttcgccgacg ccgaactgga
    36181 ccgcattcgc gttgactcac gcctgactta cgaagcattg ctggagttta cctcggagta
    36241 cattcccgag atgaccagca agctggagca ttacaccgga cgccagccga ttttcgatct
    36301 ctttgatgtc gaaaacgaaa tccagcgagc gctggaacgc aaagtagaac tgaaatccgg
    36361 tggttatctg attatcgacc agaccgaagc gatgaccacc gtggacatca ataccggggc
    36421 gtttgtcggt catcgcaatc tggacgacac cattttcaat accaatattg aagcgacgca
    36481 ggctatcgct cgccagttac ggttgcgcaa tctgggcggg attatcatta ttgatttcat
    36541 cgatatgaat aatgaagatc accgccgacg cgtgctgcac tcgctggagc aggcattgag
    36601 caaagaccgg gtgaaaacta gcgttaatgg tttttcggcg ctggggctgg tggagatgac
    36661 gcgtaaacgc acccgcgaaa gcattgagca cgtactgtgt aacgaatgcc caacctgcca
    36721 cggtcgcgga acggtgaaaa ccgtggaaac ggtatgctat gaaatcatgc gcgagattgt
    36781 tcgtgtccac catgcttacg actccgaccg tttcctggtc tatgcttctc cggcagtagc
    36841 tgaagccttg aaaggcgaag agtcacactc gctggcggaa gtggaaattt tcgttggtaa
    36901 acaggttaaa gtacaaattg aaccgctcta taaccaggag cagtttgacg tcgtaatgat
    36961 gtaaacagat gctgggccgc catccggcaa agggtttttg agtcacattt ttagcagaca
    37021 aggagtgacg ggtgaggcga ttgccgggga ttttactgct tactggagcc gcgctcgttg
    37081 tgatcgctgc cctgctggtt agcggcctgc gtattgcttt accgcatctt gacgcctggc
    37141 gtccggaaat cctcaacaaa atagaatccg cgactggcat gccggtagaa gccagtcagc
    37201 tctcagccag ctggcagaat tttggcccga cgcttgaagc acacgacatc cgtgcagaac
    37261 taaaagatgg cggcgaattt tcggttaaac gcgttactct ggcgctggat gtctggcaga
    37321 gcttgttaca tatgcgctgg cagtttcgcg acctcacttt ctggcagctg cgctttcgca
    37381 ccaacactcc tatcaccagc ggtggtggta atgatagcct ggaagccagt cacatcagcg
    37441 atctgtttct tcgtcaattt gaccatttcg atctccgcga cagtgaagtc agttttctga
    37501 cgccatccgg tcagcgcgcc gagctggcga tcccacaact cacctggctg aacgatccac
    37561 gtcgacaccg tgcggaaggc ctggtaagcc tctccagcct taccggacag cacggcgtga
    37621 tgcaggtgcg catggatttg cgcgatgatg aggggttgtt aagcaatggt cgcgtctggc
    37681 tacaggcgga tgacatcgac ctgaagccgt ggctcggtaa atggatgcag gacaatattg
    37741 ctctggaaac ggcacagttc tcccttgaag gctggatgac gatcgacaaa ggcgatgtaa
    37801 ccggcggtga cgtctggctg aaacagggcg gtgccagctg gttgggcgag aagcaaacgc
    37861 atacgctgtc ggtggataat ctgaccgcgc atattacgcg tgaaaatccg ggctggcagt
    37921 tctctattcc cgatacacgg atcacgatgg acggcaaacc ctggccgagc ggagcattga
    37981 cgctggcctg ggtaccggaa caggacgttg gcggcaaaga caataaacgc agtgacgaac
    38041 tccggattcg cgccagtaat ctggagctgg caggcctgga gggcatacgc ccgctggccg
    38101 cgaaactttc acctgcactg ggtgatgttt ggcgctccac acaaccgagc ggcaagatta
    38161 acactctggc gctggatatc ccgcttcagg cggcagacaa gacccgtttt caggcatcgt
    38221 ggagcgatct ggcctggaag caatggaaat tattaccggg tgcggaacac ttctccggga
    38281 cgctttccgg cagcgttgaa aatggtttgc ttaccgcgtc gatgaagcag gcaaagatgc
    38341 cttacgaaac ggtattccgt gcgccactgg aaatcgccga cggccaggca actataagct
    38401 ggctgaacaa tgacaaaggt ttccagctgg atgggcgtaa tattgacgtt aaagccaaag
    38461 ccgtccatgc gcgcggcggt tttcgttacc tgcaacctgc taacgatgaa ccctggctgg
    38521 gtattctggc tggcatcagt accgatgatg gttcacaagc ctggcgctat ttcccggaaa
    38581 acttgatggg taaagacctg gttgattact taagtggcgc gattcagggc ggtgaagcgg
    38641 ataacgcgac gctggtttat ggtggcaatc cacaactctt cccctataaa cacaacgaag
    38701 gtcagtttga agtgctggtg ccgctgcgca acgcgaagtt tgccttccag ccggactggc
    38761 ctgcattaac taaccttgat attgaactgg actttattaa cgacggttta tggatgaaaa
    38821 ccgatggcgt taatctgggc ggcgtgcgcg cgagtaatct caccgcagtg atccctgact
    38881 actcgaaaga aaaactgctg attgacgctg acattaaagg tccgggtaaa gccgttggcc
    38941 cttactttga tgagacaccg ctgaaagatt ctctgggggc gaccctgcaa gaactccagc
    39001 tcgacggcga tgtgaatgct cgcttacatc ttgatatccc gctgaacggc gaactggtaa
    39061 ccgcgaaagg tgaagtgacg ctgcgtaata acagtctgtt tatcaaacca ctcgacagca
    39121 ccctgaaaaa tttgagcggt aaattcagct ttatcaatag cgatctgcaa agtgaaccac
    39181 tgacagcaag ctggtttaat cagccgttga acgtggattt ttccaccaaa gaaggggcaa
    39241 aagcctacca ggtagcggta aacctcaacg gtaactggca accggcgaaa accggcgttc
    39301 tgcctgaagc ggtgaacgaa gcattgagtg gcagcgtggc gtgggatggt aaagtgggca
    39361 ttgatctgcc ttatcatgct ggtgcgacct ataacataga gctgaacggc gatctaaaga
    39421 atgtgagcag tcacttacct tcaccgttag ccaaacctgc gggtgaacca ctagcggtaa
    39481 acgttaaggt tgatggcaat ctcaacagct ttgaattaac cggacaggct ggtgcggata
    39541 atcatttcaa tagccgctgg ttgctcggtc aaaagctgac gctcgatcgt gctatttggg
    39601 cggcagacag taaaacgctc ccgccgttgc cggaacaaag tggcgttgaa ctcaatatgc
    39661 cgccgatgaa tggtgccgag tggctggccc tgttccagaa aggcgctgcg gagagtgtcg
    39721 gtggtgcagc gagtttccca caacacataa cgttacgtac gcctatgttg tcactgggaa
    39781 atcagcaatg gaataacctg agtattgttt cgcaaccgac ggcaaatggc accctggttg
    39841 aagcgcaagg gcgtgaaatc aacgccacgc tagcgatgcg taataacgcg ccgtggctgg
    39901 cgaatatcaa atatctttat tacaacccga gcgtggcgaa aactcgtggt gattcaacgc
    39961 cgtcatcacc tttcccgaca acggagcgca ttaacttccg tggctggccg gacgcccaaa
    40021 tacgatgcac agagtgctgg ttctgggggc aaaaattcgg tcgcattgac agtgatatca
    40081 ccatttctgg cgatacgtta acgctgacca atggactgat tgatactggt ttctcgcggc
    40141 ttactgccga tggtgaatgg gttaataatc cggggaatga acgtacctcg ctgaaaggaa
    40201 aactgcgcgg gcagaaaatt gatgccgccg cagaattttt tggtgtcacg acgcccatac
    40261 gccagtcgtc atttaatgtg gattacgatt tacactggcg caaagcaccc tggcagccag
    40321 atgaagcgac gttgaatggc atcattcata ctcaactggg taaaggcgaa attaccgaaa
    40381 tcaataccgg acatgctggg caattgctgc gcttattgag cgtagatgcc ctgatgcgta
    40441 agctgcgttt tgatttcaga gacacttttg gcgaagggtt ctattttgac tccattcgca
    40501 gcaccgcgtg gattaaagac ggcgttatgc acaccgacga cacgctggtg gatggcctgg
    40561 aggcggatat cgccatgaaa gggtcggtaa atctggtacg tcgcgacctg aatatggaag
    40621 cggttgtcgc accagagatt tctgcgacgg tgggcgtggc tgcggctttt gcggttaacc
    40681 ccattgttgg cgcggcagtg tttgccgcca gtaaagtgct ggggccgctg tggagcaaag
    40741 tctccatttt gcgctatcac atttcgggtc cgctggacga tccgcaaatc aacgaagtgt
    40801 tgcgccaacc gcgtaaagaa aaagcgcaat gatttgacga gggcgcgtaa ttgccccaat
    40861 ctcatatgat aatcgttgcc aaaggccaac gagccggaac ataactgtag gccggatagg
    40921 gcgttcacgc cgcatccggc agccgtaaaa aatcctctac tgcagtaact aacgagtagc
    40981 aaaaacgatg agtctgaacc tggtaagtga acaattgcta gcggcgaacg gcctgaaaca
    41041 tcaggacttg ttcgcgatcc tcggtcaact ggccgaacgt cgccttgatt atggcgatct
    41101 ctattttcag tcgagctatc acgaatcctg ggttttagaa gaccgcatta ttaaagatgg
    41161 ttcttacaac atcgatcagg gcgttggtgt gcgtgcaatc agtggtgaaa aaaccggatt
    41221 tgcttacgca gaccaaatca gcctgctggc gctggaacag agtgcgcaag cggcgcgcac
    41281 catcgtccgt gatagtggtg atggcaaagt acagacgctg ggcgcggtag agcatagccc
    41341 gttgtatacc tcggtagatc cgctgcaaag catgagccgt gaagagaagc tggatatcct
    41401 gcgtcgcgtc gataaggttg cccgcgaagc ggacaagcgc gtacaagaag tgactgccag
    41461 cctcagcggc gtttatgaat taattctggt tgcggccacc gacggcacgc tggcggcgga
    41521 tgttcgtccg ctggtgcgtc tttccgtgag cgttctggtc gaagaagatg gcaaacgcga
    41581 acgcggtgcc agtggcggcg gcggtcgttt tggttatgag ttcttccttg ccgatcttga
    41641 cggcgaagtc cgtgcggatg catgggcaaa agaagcagtg cgtatggcgc tggtcaatct
    41701 ttctgccgtt gctgcaccag cgggcaccat gccggtagta cttggcgcag gttggccggg
    41761 cgtgctgttg catgaagcgg taggtcacgg tctggaaggc gacttcaacc gccgcggcac
    41821 ttcagtattt agtgggcagg tcggggagct ggtggcttca gaactgtgta ccgtggttga
    41881 tgacggcacg atggtcgatc gccgtggttc ggtggcgatt gatgacgaag gtacgccagg
    41941 ccagtacaac gtgctgattg agaacggcat tctgaaaggc tacatgcagg ataaactcaa
    42001 cgcgcgtttg atggggatga cgccgactgg caacggtcgc cgtgaatcct acgcccatct
    42061 gcccatgccg cgtatgacca acacctatat gctgccgggt aaatcgaccc cgcaggaaat
    42121 tattgaatcc gttgagtacg gtatctatgc accgaacttt ggtggcggtc aggtggatat
    42181 tacatccggc aaattcgttt tctccacttc agaagcgtat ctgattgaaa acggtaaagt
    42241 aacgaagccg gtgaaaggcg cgacgttgat tggttccggt atcgaaacca tgcagcagat
    42301 ttcgatggtt ggcaacgacc tgaaactgga taacggcgtg ggtgtctgcg gtaaagaagg
    42361 gcaaagtttg ccggttggcg tgggccagcc aacgctgaaa gttgataacc tgactgttgg
    42421 cggtactgcg taataatttc attattttca gaaggataat taatctttct acgtgcacga
    42481 acggtcccct cgctcctctg gggttagggt gaggggaacc cgttggcaca ggtttgtaga
    42541 acgtaacagt acaatatgaa ttacttctct ttcccgcgcc cgtgcatctc ctgaaacaat
    42601 ttaccgacct caacaaaata atccgtcagc gagttgatca cgacctgtac cttcagcggc
    42661 agcttatctt tttcggtata taacgcataa accgggcgtg gatctgactg ataacgcggc
    42721 agcaggatct ccagctcacc gcgattgatc tcgttgatca cccacatcag cggcacgtag
    42781 gcgatcccgg cacccgccgt tagccagcgc accagcgtca tcggatcatt agtcacaaat
    42841 ctcccttgcg ggatcaggcg agtcgagatc ccttccggtg caatcagttc aaattcattg
    42901 tcgggccgca cgctgtattc aagccatgaa tggctactta aatcggcggg tttttccggt
    42961 atgccgtatt gtgtgagata gcttttcgcg gcgcacacca ccattggcat cgcgccaaga
    43021 cggcgggaaa acaggctgga atcctgcaac gcgccgacgc ggatcaccac atccagaccg
    43081 tcggcaatca ggtcgggggc tggaattccg gtaaccagat tgacgctcaa acctgggtat
    43141 tctttcagca ttttggctgt cagcccggcg agaacatttt gtgccatagt tgaagaacag
    43201 ccaatgcgta gcgtcccgat gggggtgtta ttgaaggcat acagttgctc atgaacatcc
    43261 tgcacttcat gaagcatacg acggcagccc tggtagtaaa ttctaccggc ttcggtcagg
    43321 ccaatgctgc gtgtgctacg gtttaacagc tttacctgca actcatcttc cagttttgac
    43381 accgtctgac tgatggacga aacgctcatc tgtagctgtc tggcggcggc ggtaaaagag
    43441 ccaaattcaa ctactttggc aaacaccgac atgcgtttta gtcgttccat tattcactct
    43501 gacttaaaag tgatttagat cacataatat agataacagc ataacagtta cgctaatata
    43561 ttaaatatca atctacagca atgttgctct cgcccggctt tccatgccct tctctgcggc
    43621 gacagatgct gaaaataata acgcctgctc tctctttaca accaaggtca acatgagtct
    43681 gtttcccgtt atcgtggtgt ttgggctgtc cttcccaccg atattttttg aattgctttt
    43741 atcactggcg attttctggc tggtgcgccg ggtacttgtg ccaacaggta tctacgactt
    43801 tgtctggcat ccggcgttgt tcaacaccgc gctctattgc tgcttgtttt atttgatatc
    43861 gcgactgttc gtttgaggtt gaagtgaaaa cactaataag aaaattctcc cgtacggcca
    43921 tcacggtcgt attagtcatt ctggccttca tcgcaatttt taatgcctgg gtctattaca
    43981 ccgaatcccc ctggacgcgt gacgcgcgct ttagcgctga cgtcgttgcg atcgcgccgg
    44041 acgtttctgg actcattacc caggtgaatg ttcatgataa ccagctggtg aaaaaaggac
    44101 agatactgtt caccatcgac cagccgcgct atcaaaaggc gcttgaggaa gcgcaagccg
    44161 atgttgctta ttatcaggta ctggcacagg agaaacgcca ggaggccgga cgtcgtaacc
    44221 gtctcggtgt gcaggcgatg tctcgcgaag agatcgacca ggctaacaac gtactacaaa
    44281 cggttctgca tcagttagcg aaagcgcagg cgacccgcga tctggcaaaa ctggatcttg
    44341 aacgcacggt gatccgcgcg ccagcagatg gctgggtgac caacctcaac gtctataccg
    44401 gtgagtttat tactcgagga tcaacggcgg ttgcgctggt gaaacagaac tccttctatg
    44461 tactggccta tatggaagaa actaagctgg aaggggtgcg tccggggtat cgtgcagaga
    44521 tcacgccgct tggcagtaac aaagtgctga aagggactgt tgatagtgtt gccgcagggg
    44581 tcaccaacgc cagcagcacg cgtgacgaca aagggatggc gactatagac tctaaccttg
    44641 aatgggtgcg tcttgcgcaa cgtgttccgg ttcgtattcg tctcgacaac cagcaagaga
    44701 acatctggcc tgcgggcacc actgctacag tggtggtcac tggcaaacaa gatcgcgacg
    44761 aaagccagga ttcgttcttc cgtaaaatgg cccatcgcct gcgtgagttt ggttaatcac
    44821 gatgggtatt ttctccattg ctaaccaaca tattcgcttt gcggtaaaac tggcgaccgc
    44881 cattgtactg gcgctgtttg ttggctttca cttccagctg gaaacgccac gctgggcggt
    44941 actgacagcg gcgattgttg ccgccggtcc ggcctttgct gcgggaggtg aaccgtattc
    45001 tggcgctatt cgttatcgtg gctttttgcg catcatcggc acatttattg gctgtattgc
    45061 cggactggtg atcatcattg cgatgatccg cgcaccatta ttgatgattc tggtgtgctg
    45121 tatctgggcc ggtttttgta cctggatatc ctcgctggta cgaatagaaa actcgtacgc
    45181 gtgggggctg gccggttata ccgcgctgat cattgtgatc accattcagc cggaaccatt
    45241 gcttacgccg cagtttgccg tcgaacgttg tagcgagatc gttatcggta ttgtgtgtgc
    45301 gattatggcg gatttgctct tttctccgcg atcgatcaaa caagaagtgg atcgagagct
    45361 ggaaagtttg ctggtcgcgc aatatcaatt aatgcaactc tgtatcaagc atggcgatgg
    45421 tgaagttgtc gataaagcct ggggcgacct ggtgcgacgc accacggcgc tacaaggcat
    45481 gcgcagcaac ctgaatatgg aatcttcccg ctgggcgcgg gccaatcgac gtttaaaagc
    45541 gatcaatacg ctatcgctga cgctgattac ccaatcctgc gaaacttatc ttattcagaa
    45601 tacgcgcccg gaattgatca ctgatacttt ccgcgaattt tttgacacgc cggtagaaac
    45661 cgcgcaggac gtccacaagc agctcaaacg cctgcggaga gttatcgcct ggaccgggga
    45721 acgggaaacg cctgtcacca tttatagctg ggtcgcggcg gcaacgcgtt atcagcttct
    45781 caagcgcggc gttatcagta acacaaaaat caacgccacc gaagaagaga tcctgcaagg
    45841 cgaaccggaa gtcaaagtag agtcagccga acgtcatcat gcgatggtta acttctggcg
    45901 aaccacactt tcctgcattc tgggcacgct tttctggctg tggacgggct ggacttccgg
    45961 cagtggtgca atggtgatga ttgcggtagt gacgtcactg gcaatgcgtt tgccgaatcc
    46021 acgcatggtg gcgatcgact ttatctacgg gacgctggcc gcgctgccgt tagggctgct
    46081 ctactttttg gtgattatcc ctaataccca acagagcatg ttgctgctgt gtattagcct
    46141 ggcagtgctg ggatttttcc tcggtataga agtacagaaa cggcgactgg gctcgatggg
    46201 ggcgctggcc agcaccataa atattatcgt gctggataac ccgatgactt tccatttcag
    46261 tcagtttctc gacagcgcat tagggcaaat cgtcggctgt gtgctcgcgt tcaccgttat
    46321 tttgcttgtg cgggataaat cgcgcgacag gaccggacgt gtactgctta atcagtttgt
    46381 ttctgccgct gtttccgcga tgactaccaa tgtggcacgt cgtaaagaga accacctccc
    46441 ggcactttat cagcagctgt ttttgctgat gaataagttc ccaggggatt tgccgaaatt
    46501 tcgcctggcg ctgacgatga ttatcgcgca ccagcgcctg cgtgatgcgc cgatcccggt
    46561 taacgaggat ttatcggcgt ttcaccgaca aatgcgccgc acagcagacc atgtgatatc
    46621 tgcccgtagc gatgataaac gtcgtcggta ctttggccag ttgctggaag aactggaaat
    46681 ctaccaggaa aagctacgca tctggcaagc gccaccgcag gtgacggaac cggttcatcg
    46741 gctggcgggg atgctccata agtatcaaca tgcgttgacc gatagttaag tcaaaaccga
    46801 cgccaaaagc gtcggttttt tcatggctat acttagcgat gcacggcaga actcgccgcg
    46861 aaacgtgacg gtggcaacag atgaatattt atacctttga ttttgatgag attgagagtc
    46921 aggaggattt ttatcgtgac tttagccaaa cctttggtct ggcgaaagat aaggtacgcg
    46981 atctcgactc actatgggat gtgttaatga acgatgtcct gccgctacca cttgagattg
    47041 aatttgttca tctgggagag aaaacgcgtc gccgttttgg cgcgttaata ttgctgtttg
    47101 atgaggcaga ggaagagctg gaagggcatt tgcgttttaa tgttcgtcat tagcgcgaaa
    47161 aaaagccccc gaaccggggg caatatcgtc ggacaagacg atgagggttt atttgtacag
    47221 ttcagccgta gcgtgccagg tgtcaccgct acgagcttca gtaatctggt aggccgttgc
    47281 gcctttctct tccgcttttt tgttcagcat ttcacgcata tccattggcg aagacgccac
    47341 accacttacg gatacggtcc cgattgcttc acgattttgt gcttgtgcag catcaatgga
    47401 gtcggcagcg aatgcaccga aagagagaac agaaagtacg cttaatgcag ctacagtggt
    47461 tttgattttc atgattttta cctcgacata atcttttagc tgggtctttg tttcgtgacc
    47521 catatcacaa aatcaagtat acactaatta ttgaactaat taataccacg ctaactgttt
    47581 cagttgatac taagtgttaa aaatg
//
LOCUS       DAPGUL010000023        46177 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.023, whole genome shotgun sequence.
ACCESSION   DAPGUL010000023 DAPGUL010000000
VERSION     DAPGUL010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 46177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46177
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.023"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..152
                     /locus_tag="RHX21_001450"
     CDS             <1..152
                     /locus_tag="RHX21_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDV1986661.1"
                     /translation="RLLRRDRPDIAVRYYYKGVLWSPGYFANSCGGAPISVIRQYIEQ
                     QQTPG"
     gene            complement(283..1605)
                     /locus_tag="RHX21_001451"
     CDS             complement(283..1605)
                     /locus_tag="RHX21_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312649.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HDV1986662.1"
                     /translation="MTKFSVVVAGGGSTFTPGIVLMLLANQDRFPLRALKFYDNDGAR
                     QEVIAEACKVILKEKAPDIAFSYTTDPEVAFSDVDFVMAHIRVGKYPMRELDEKIPLR
                     HGVVGQETCGPGGIAYGMRSIGGVLELVDYMEKYSPNAWMLNYSNPAAIVAEATRRLR
                     PNAKILNICDMPIGIESRMAQIVGLQDRKQMRVRYYGLNHFGWWTSIEDLQGNDLMPQ
                     LRQYVSKHGYVPPQQDTHTEASWNDTYAKARDVQALAPDTLPNTYLKYYLFPDYVVQH
                     SNPEHTRANEVMEHREKQVFDACRAITAAGNSAAGKLEIDEHASYIVDLAAAIAFNTQ
                     ERMLLIVPNNGAIHNFDDEAMVEIPCLVGHNGPEPLVVGDIPQFQKGLMSQQVAVEKL
                     VVDAWEQRSYQHLWQAITLSKTVPSASVAKAILDELLKANKAYWPELR"
     gene            complement(1605..3221)
                     /locus_tag="RHX21_001452"
     CDS             complement(1605..3221)
                     /locus_tag="RHX21_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312650.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDV1986663.1"
                     /translation="MLSQIQRFGGAMFTPVLLFPFAGIVVGLAILLQNPMFVGESLTD
                     PNSLFAQIVHIIEEGGWTVFRNMPLIFAVGLPIGLAKQAQGRACLAVMVSFLTWNYFI
                     NAMGMTWGSYFGVDFTQDAVAGSGLTMMAGIKTLDTSIIGAIIISGIVTALHNRLFDK
                     KLPVFLGIFQGTSYVVIIAFLVMIPCAWLTLLGWPKVQMGIESLQAFLRSAGALGVWV
                     YTFLERILIPTGLHHFIYGPFIFGPAAVEGGIQMYWAQHLQEFSLSAEPLKSLFPEGG
                     FALHGNSKIFGAVGISLAMYFTAAPENRVKVAGLLIPATLTAMLVGITEPLEFTFLFI
                     SPLLFAVHAVLAASMSTVMYLFGVVGNMGGGLIDQVLPQNWIPMFSNHADMMLTQIAI
                     GLCFTLLYFVVFRTLILQFNMCTPGREDAEVKLYSKAEYKASRGQTTAAEPKKELDQA
                     AGILQALGGVGNISSINNCATRLRIALHDMSQTLDDEVFKKLGAHGVFRSGDAIQVII
                     GLHVSQLREQLDSLINSHQSAENVAITEAV"
     gene            3517..4233
                     /locus_tag="RHX21_001453"
     CDS             3517..4233
                     /locus_tag="RHX21_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDV1986664.1"
                     /translation="MIYKSIAERLRIRLNSADFTLNSLLPGEKKLAEEFAVSRMTIRK
                     AIDLLVAWGLVVRRHGSGTYLVRKDVLHQTASLTGLVEVLKRQGKTVTSQVLIFEIMP
                     APPAIASQLRIQINEQIYFSRRVRFVEGKPLMLEDSYMPVKLFRNLSLQHLEGSKFEY
                     IEQECGILIGGNYESLTPVLADRLLARQMKVAEHTPLLRITSLSYSESGEFLNYSVMF
                     RNASEYQVEYHLRRLHPEKS"
     gene            complement(4230..5891)
                     /locus_tag="RHX21_001454"
     CDS             complement(4230..5891)
                     /locus_tag="RHX21_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312652.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transporter"
                     /protein_id="HDV1986665.1"
                     /translation="MSDIALTVSILALVAVVGLFIGNVKFRGIGLGIGGVLFGGIIVG
                     HFVSQAGMTLSSDMLHVIQEFGLILFVYTIGIQVGPGFFASLRVSGLRLNLFAVLIVI
                     IGGLVTAILHKLFDIPLPVVLGIFSGAVTNTPALGAGQQILRDLGTPMEMVDQMGMSY
                     AMAYPFGICGILFTMWMLRVIFRVNVETEAQQHESSRTNGGALIKTINIRVENPNLHD
                     LAIKDVPILNGDKIICSRLKREETLKVPSPDTIIQLGDLLHLVGQPADLHNAQLVIGQ
                     EVDTSLSTKGTDLRVERVVVTNENVLGKRIRDLHFKERYDVVISRLNRAGVELVASGD
                     ISLQFGDILNLVGRPSAIDAVANVLGNAQQKLQQVQMLPVFIGIGLGVLLGSIPVFVP
                     GFPAALKLGLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLSVVGLKS
                     GGDFVNTLVNGEGLSWIGYGALITAVPLITVGILARMLAKMNYLTMCGMLAGSMTDPP
                     ALAFANNLHPTSGAAALSYATVYPLVMFLRIITPQLLAVLFWSIG"
     gene            complement(6087..6515)
                     /gene="ibpB"
                     /locus_tag="RHX21_001455"
     CDS             complement(6087..6515)
                     /gene="ibpB"
                     /locus_tag="RHX21_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709512.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock chaperone IbpB"
                     /protein_id="HDV1986666.1"
                     /translation="MRNFDLSPLMRQWIGFDKLANALQNAGESQSFPPYNIEKSDDNH
                     YRITLALAGFRQEDLEIQLEGTRLSVKGTPEQPKEEKKWLHQGLMNQPFSLSFTLAEN
                     MEVSGATFVNGLLHIDLIRNEPEPIAAQRIAISERPALNS"
     gene            complement(6627..7040)
                     /gene="ibpA"
                     /locus_tag="RHX21_001456"
     CDS             complement(6627..7040)
                     /gene="ibpA"
                     /locus_tag="RHX21_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006687722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock chaperone IbpA"
                     /protein_id="HDV1986667.1"
                     /translation="MRNFDLSPLYRSAIGFDRLFNHLENNQSQSNGGYPPYNVELVDE
                     NHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQKERTYLYQGIAERNFERKFQLA
                     ENIHVRGANLVNGLLYIDLERVIPEAKKPRRIEIN"
     misc_feature    complement(7034..7106)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01832"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ROSE (Repression Of Heat Shock gene Expression)
                     occurs in the 5'-region of heat shock genes and acts as an
                     RNA thermometer to modulate expression; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF01832"
     gene            7346..7678
                     /locus_tag="RHX21_001457"
     CDS             7346..7678
                     /locus_tag="RHX21_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418143.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceK/YidQ family lipoprotein"
                     /protein_id="HDV1986668.1"
                     /translation="MIRNVLLAFMICSGMTLLGGCSSVMSHTGGKEGTYPGTRASATM
                     IGDDETNWGTKSLAILDMPFTAVMDTLLLPWDVFRKDSSVRSRVEKSEANAQATNAVI
                     PPARMPDN"
     gene            complement(7680..8894)
                     /locus_tag="RHX21_001458"
     CDS             complement(7680..8894)
                     /locus_tag="RHX21_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312656.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3748 domain-containing protein"
                     /protein_id="HDV1986669.1"
                     /translation="MKQITFAPRNHLLTNTNTWTPDSQWLVFDVRPSGASFTGETIER
                     VNIHTGEVEVIYRASQGAHVGVVTVHPKSEKYVFIHGPENPDETWHYDFHHRRGVIAE
                     GGKVSNLDAMDITAPYTPGALRGGSHVHVFSPNGERVSFTYNDHVMHELDPALDLRNV
                     GVAAPFGPVNVQKQHPREYSGSHWCVLVSKTTPTPQPGSDEINRAYEEGWVGNHALAF
                     IGDTLSPKGEKVPELFIVELPQDEAGWKAAGDAPLSGTETTLPAPPRGVVQRRLTFTH
                     HRAYPGLVNVPRHWVRCNPQGTQIAFLMRDDNGIVQLWLISPQGGEPRQLTHNKTDIQ
                     SAFNWHPSGEWLGFVLDNRIACAHAQSGEVEYLTEHHANSPSADAVVFSPDGQWLAWM
                     EGGQLWITETDR"
     gene            8995..10059
                     /gene="cbrA"
                     /locus_tag="RHX21_001459"
     CDS             8995..10059
                     /gene="cbrA"
                     /locus_tag="RHX21_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418145.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin M resistance protein"
                     /protein_id="HDV1986670.1"
                     /translation="MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSK
                     PCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHA
                     FDLWMKSLIPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHITARYLVGADGANSM
                     VRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNAITDCYSWSISKDGYFIFGGAY
                     PMKDGQTRFTTLKEKMSAFQFQFGKTVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAG
                     FISASSLEGISYALDSADILRSVLLKQPEKLNTAYWRATRKLRLKLFGKIVKSRCLTA
                     PALRKWIMRSGVAHIPQLKD"
     gene            complement(10056..11190)
                     /locus_tag="RHX21_001460"
                     /pseudo
     CDS             complement(10056..11190)
                     /locus_tag="RHX21_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709507.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(11265..12413)
                     /gene="dgoD"
                     /locus_tag="RHX21_001461"
     CDS             complement(11265..12413)
                     /gene="dgoD"
                     /locus_tag="RHX21_001461"
                     /EC_number="4.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020077623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactonate dehydratase"
                     /protein_id="HDV1986671.1"
                     /translation="MKITKITTYRLPPRWMFLKIETDEGVVGWGEPVIEGRARTVEAA
                     VHELGDYLIGQDPSRINDLWQVMYRAGFYRGGPILMSAIAGIDQALWDIKGKVLNAPV
                     WQLMGGLVRDKIKAYSWVGGDRPADVIDGIKTLREIGFDTFKLNGCEELGPIDNSRAV
                     DAAVNTVAQIREAFGNQIEFGLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAE
                     YYPKLAAQTHIPLAAGERMFSRFDFKRVLEAGGISILQPDLSHAGGITECYKIAGMAE
                     AYDVTLAPHCPLGPIALAACLHIDFVSYNAVLQEQSMGIHYNKGAELLDFVKNKEDFS
                     MVGGFFKPLTKPGLGVEIDEAKVIEFSKNAPDWRNPLWRHEDNSVAEW"
     gene            complement(12410..13027)
                     /gene="dgoA"
                     /locus_tag="RHX21_001462"
     CDS             complement(12410..13027)
                     /gene="dgoA"
                     /locus_tag="RHX21_001462"
                     /EC_number="4.1.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-6-phosphogalactonate aldolase"
                     /protein_id="HDV1986672.1"
                     /translation="MQWQTKLPLIAILRGITPDEALAHVGAVIDAGFDAVEIPLNSPQ
                     WEQSIPAIVDAYGDKALIGAGTVLKPEQVDALARMGCQLIVTPNIHSEVIRRAVGYGM
                     TVCPGCATATEAFTALEAGAQALKIFPSSAFGPQYIKALKAVLPSDIAVFAVGGVTPE
                     NLAQWIDAGCAGAGLGSDLYRAGQSVERTAQQAAAFVKAYREAVQ"
     gene            complement(13011..13889)
                     /gene="dgoK"
                     /locus_tag="RHX21_001463"
     CDS             complement(13011..13889)
                     /gene="dgoK"
                     /locus_tag="RHX21_001463"
                     /EC_number="2.7.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxygalactonokinase"
                     /protein_id="HDV1986673.1"
                     /translation="MTARYIAIDWGSTNLRAWLYQSDHCLESRQSEAGVTRLNGKSPA
                     AVLAEVTTDWREEKTPVVMAGMVGSNVGWKVAPYLSVPACFSSIGEQLTSVGDNIWII
                     PGLCVSHDDNHNVMRGEETQLIGARALAPSSLYVMPGTHCKWVQADSQQINDFRTVMT
                     GELHHLLLNHSLIGAGLPPQENSADAFTAGLERGLNTPAILPQLFEVRASHVLGTLPR
                     EQVSEFLSGLLIGAEVASMRDYVAHQHAITLVAGTSLTARYQQAFQAMGCDVTAVAGD
                     TAFQAGIRSIAHAVAN"
     gene            complement(13886..14575)
                     /gene="dgoR"
                     /locus_tag="RHX21_001464"
     CDS             complement(13886..14575)
                     /gene="dgoR"
                     /locus_tag="RHX21_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-galactonate utilization transcriptional
                     regulator DgoR"
                     /protein_id="HDV1986674.1"
                     /translation="MTLNKTDRIVITLGKQIVHGKYVPGSPLPAEAELCEEFATSRNI
                     IREVFRSLMAKRLIEMKRYRGAFVAPRNQWNYLDTDVLQWVLENDYDPRLISAMSEVR
                     NLVEPAIARWAAERATSSDLAQIESALNEMIANNQDREAFNEADIRYHEAVLQSVHNP
                     VLQQLSIAISSLQRAVFERTWMGDEANMPQTLQEHKALFDAIRHQDGDAAEQAALTMI
                     ASSTRRLKEIT"
     gene            14853..15509
                     /locus_tag="RHX21_001465"
     CDS             14853..15509
                     /locus_tag="RHX21_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986675.1"
                     /translation="MKLNFKGFFKAAGLFPLALMLSGCISYALVSHTAKGSSGKYQSQ
                     SDTITGLSQAKDSNGTKGYVFVGESLDYLITDGADDIVKMLNDPALNRHNIQVADDAR
                     FVLNAGKKKFTGTISLYYYWNNEEEKALATHYGFACGVQHCTRSLENLKGTIHEKNKN
                     MDYSKVMAFYHPFKVRFYEYYSPRGIPDGVSAALLPVTVTLDIITAPLQFLVVYAVNQ
                     "
     gene            complement(15555..16367)
                     /gene="yidA"
                     /locus_tag="RHX21_001466"
     CDS             complement(15555..16367)
                     /gene="yidA"
                     /locus_tag="RHX21_001466"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HDV1986676.1"
                     /translation="MAIKLIAIDMDGTLLLPDHTISPAVKNAIAAARARGVNVVLTTG
                     RPYAGVHNYLKELHMELPGDYCITYNGALVQKAADGSTVAQTALSYDDYRFLEKLSRE
                     VGSHFHALDRTTLYTANRDISYYTVHESFVATIPLVFCEAEKMDPNTQFLKVMMIDEP
                     AILDQAIARIPQEVKEKYTVLKSAPYFLEILDKRVNKGTGVKSLADVLGIKPEEIMAI
                     GDQENDIAMIEYAGVGVAMDNAIPSVKEVANFVTKSNLEDGVAFAIEKYVLN"
     gene            complement(16482..16880)
                     /locus_tag="RHX21_001467"
     CDS             complement(16482..16880)
                     /locus_tag="RHX21_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418153.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidB family protein"
                     /protein_id="HDV1986677.1"
                     /translation="MGLFDEVVGAFLKGDAGKYQAILSWVEEQGGIQVLLEKLQSGGL
                     GAILSTWLSNQQGNQSVSGEQLESALGTNAVSDLGQKLGVDTSTASSLLAEQLPKIID
                     ALSPQGEVSPQANNDLLSAGMELLKGKLFR"
     gene            complement(17120..19534)
                     /gene="gyrB"
                     /locus_tag="RHX21_001468"
     CDS             complement(17120..19534)
                     /gene="gyrB"
                     /locus_tag="RHX21_001468"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HDV1986678.1"
                     /translation="MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVV
                     DNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLHAGG
                     KFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGET
                     EKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHY
                     EGGIKAFVEYLNKNKTPIHPNIFYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQR
                     DGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLIAVVSVKVPDPKFSS
                     QTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMT
                     RRKGALDLAGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKI
                     LNVEKARFDKMLSSQEVATLITALGCGIGRDEYNPDKLRYHSIIIMTDADVDGSHIRT
                     LLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATL
                     HTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTEADLSDEQ
                     TVTRWVNALVSELNDKEQHGSQWKFDVHTNAEQNLFEPIVRVRTHGVDTDYPLDHEFI
                     TGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFEQALDWLVKESRRGLSIQRYK
                     GLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALK
                     AANIDI"
     gene            complement(19563..20636)
                     /gene="recF"
                     /locus_tag="RHX21_001469"
     CDS             complement(19563..20636)
                     /gene="recF"
                     /locus_tag="RHX21_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HDV1986679.1"
                     /translation="MSLTRLLIRDFRNIETADLALSPGFNFLVGANGSGKTSVLEAIY
                     TLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERETAIGLTKDKQGDSKVRIDGTDG
                     HKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEPGFFTAWSNLKRLLKQ
                     RNAALRQVTRYEQLRPWDKELIPLAEQISTWRAEYSAGIAADMADTCKQFLPEFSLTF
                     SFQRGWEKETEYAEVLERNFERDRQLTYTAHGPHKADLRIRADGAPVEDTLSRGQLKL
                     LMCALRLAQGEFLTRESGRRCLYLIDDFASELDDERRGLLASRLKATQSQVFVSAISA
                     EHVIDMSDENSKMFTVEKGKITD"
     gene            complement(20636..21736)
                     /gene="dnaN"
                     /locus_tag="RHX21_001470"
     CDS             complement(20636..21736)
                     /gene="dnaN"
                     /locus_tag="RHX21_001470"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006177590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HDV1986680.1"
                     /translation="MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSL
                     TGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSG
                     RSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLF
                     ETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQI
                     GSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNE
                     KFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCE
                     NVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL"
     gene            complement(21741..23144)
                     /gene="dnaA"
                     /locus_tag="RHX21_001471"
     CDS             complement(21741..23144)
                     /gene="dnaA"
                     /locus_tag="RHX21_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HDV1986681.1"
                     /translation="MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPN
                     RFVLDWVRDKYLNNINGLLTSFCGADAPQLRFEVGTKPVTQTPQAAVTSNVAAPAQVA
                     QTQPQRAAPSTRSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADN
                     PGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNA
                     IEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEIN
                     GVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVR
                     ELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVA
                     DLLSKRRSRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREE
                     SHDIKEDFSNLIRTLSS"
     gene            23441..23521
                     /locus_tag="RHX21_001472"
     CDS             23441..23521
                     /locus_tag="RHX21_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986682.1"
                     /translation="MTIDKNWLNRSNKDPGRSLRFTHQPV"
     gene            23751..23891
                     /gene="rpmH"
                     /locus_tag="RHX21_001473"
     CDS             23751..23891
                     /gene="rpmH"
                     /locus_tag="RHX21_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001686914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HDV1986683.1"
                     /translation="MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKGRARLTV
                     SK"
     gene            23908..24267
                     /gene="rnpA"
                     /locus_tag="RHX21_001474"
     CDS             23908..24267
                     /gene="rnpA"
                     /locus_tag="RHX21_001474"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014172301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HDV1986684.1"
                     /translation="MVKLAFPRELRLLTPSQFTFVFQQPQRAGTPQITILGRLNSLGH
                     PRIGLTVAKKNVRRAHERNRIKRLTRESFRLRQHELPAMDFVVVAKKGVADLDNRALS
                     EALEKLWRRHCRLARGS"
     gene            24231..24488
                     /gene="yidD"
                     /locus_tag="RHX21_001475"
     CDS             24231..24488
                     /gene="yidD"
                     /locus_tag="RHX21_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HDV1986685.1"
                     /translation="MAPPLSPGSRVLIALIRVYQRLISPLLGPHCRFTPTCSSYGIEA
                     LRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFDTREH"
     gene            24491..26137
                     /gene="yidC"
                     /locus_tag="RHX21_001476"
     CDS             24491..26137
                     /gene="yidC"
                     /locus_tag="RHX21_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDV1986686.1"
                     /translation="MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAA
                     GSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLET
                     SPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNT
                     FTKTFVLKRGDYAVNVNYNVQNAGEKPLEISSFGQLKQSITLPPHLDTGSSNFALHTF
                     RGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYT
                     ANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLW
                     FISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQA
                     MRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAP
                     FALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLW
                     FPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS"
     gene            26243..27607
                     /gene="mnmE"
                     /locus_tag="RHX21_001477"
     CDS             26243..27607
                     /gene="mnmE"
                     /locus_tag="RHX21_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HDV1986687.1"
                     /translation="MSDNDTIVAQATPPGRGGVGILRISGFKAREVAETVLGKLPKPR
                     YADYLPFKDADGSVLDQGIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTIPG
                     LRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLV
                     EALTHLRIYVEAAIDFPDEEIDFLSDGKIEAQLNDVIADLDAVRAEARQGSLLREGMK
                     VVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLRE
                     ASDEVERIGIERAWQEIEQADRVLFMVDGTTTDAVDPAEIWPEFIARLPAKLPITVVR
                     NKADITGETLGMSEVNGHALIRLSARTGEGVDVLRNHLKQSMGFDTNMEGGFLARRRH
                     LQALEQAAEHLQQGKAQLLGAWAGELLAEELRLAQQNLSEITGEFTSDDLLGRIFSSF
                     CIGK"
     gene            27850..27924
                     /gene="tnaC"
                     /locus_tag="RHX21_001478"
     CDS             27850..27924
                     /gene="tnaC"
                     /locus_tag="RHX21_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophanase leader peptide"
                     /protein_id="HDV1986688.1"
                     /translation="MNILHICVTSKWFNIDNKIVDHRP"
     gene            28145..29560
                     /gene="tnaA"
                     /locus_tag="RHX21_001479"
     CDS             28145..29560
                     /gene="tnaA"
                     /locus_tag="RHX21_001479"
                     /EC_number="4.1.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709490.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophanase"
                     /protein_id="HDV1986689.1"
                     /translation="MENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSE
                     DVFIDLLTDSGTGAVTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHQG
                     RGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFD
                     TGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAK
                     KYDIPVVMDSARFAENAYFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPM
                     GGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYR
                     IAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIR
                     AVEIGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIK
                     GLTFTYEPKVLRHFTAKLKEV"
     gene            29651..30898
                     /gene="tnaB"
                     /locus_tag="RHX21_001480"
     CDS             29651..30898
                     /gene="tnaB"
                     /locus_tag="RHX21_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low affinity tryptophan permease TnaB"
                     /protein_id="HDV1986690.1"
                     /translation="MTDQAEKKHSAFWGVMVIAGTVIGGGMFALPVDLAGAWFFWGAF
                     ILIIAWFSMLHSGLLLLEANLNYPVGSSFNTITKDLIGNTWNIISGITVAFVLYILTY
                     AYISANGAIISETISMNLGYHANPRIVGICTAIFVASVLWLSSLAASRITSLFLGLKI
                     ISFVIVFGSFFFQVDYSILRDATSSTAGTSYFPYIFMALPVCLASFGFHGNIPSLIIC
                     YGKRKDKLIKSVVFGSLLALVIYLFWLYCTMGNIPRESFKAIISSGGNVDSLVKSFLG
                     TKQHGIIEFCLLVFSNLAVASSFFGVTLGLFDYLADLFKIDNSHGGRFKTVLLTFLPP
                     ALLYLIFPNGFIYGIGGAGLCATIWAVIIPAVLAIKARKKFPNQMFTVWGGNLIPAIV
                     ILFGITVILCWFGNVFNVLPKFG"
     gene            31030..32205
                     /gene="mdtL"
                     /locus_tag="RHX21_001481"
     CDS             31030..32205
                     /gene="mdtL"
                     /locus_tag="RHX21_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtL"
                     /protein_id="HDV1986691.1"
                     /translation="MSRFLICSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAF
                     SVYLAGMAAAMLFAGKVADRSGRKPVAIPGAALFIIASVFCSLAETSTLFLAGRFLQG
                     LGAGCCYVVAFAILRDTLDDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKFPWQSLF
                     WAMAMMGIAVLMLSLFILKETRPAAPAASDKPRENSESLLNRFFLSRVVITTLSVSVI
                     LTFVNTSPVLLMEIMGFERGEYATIMALTAGVSMTVSFSTPFALGIFKPRTLMITSQV
                     LFLAAGITLAVSPSHAVSLFGITLICAGFSVGFGVAMSQALGPFSLRAGVASSTLGIA
                     QVCGSSLWIWLAAVVGIGAWNMLIGILIACSIVSLLLIMFVAPGRPVAAHEEIHHHA"
     gene            32180..33139
                     /gene="yidZ"
                     /locus_tag="RHX21_001482"
     CDS             32180..33139
                     /gene="yidZ"
                     /locus_tag="RHX21_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator YidZ"
                     /protein_id="HDV1986692.1"
                     /translation="MKKSITTLDLNLLLCLQLLMQERSVTKAAKRINVTPSAVSKSLA
                     KLRAWFDDPLFVNSPLGLSPTPLMVSMEQNLAEWMQMSNLLLDKPHHQTPRGLKFELA
                     AESPLMMIMLNALSKQIYQRYPQATIKLRNWDYDSLDAITRGEVDIGFSGRESHPRSR
                     ELLSSLPLAIDYEVLFSDVPCVWLRKDHPALHQTWNLDTFLRYPHISICWEQSDTWAL
                     DNVLQELGRERTIAMSLPEFEQSLFMAAQPDNLLLATAPRYCQYYNQLHQLPLVALPL
                     PFDESQQKKLEVPFTLLWHKRNSHNPKIVWLRETIKNLYASMA"
     gene            33296..34045
                     /locus_tag="RHX21_001483"
     CDS             33296..34045
                     /locus_tag="RHX21_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709485.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="HDV1986693.1"
                     /translation="MATHFARGILTEGHLISVRLPSQCHQEARNIPPHRQSRFLASRG
                     LLAELMFMLYGIGELPEIVTLPKGKPVFSDKNLPSFSISYAGNMVGVALTTEGECGLD
                     MELQRATRGFHSPHAPDNHTFSSNESLWISKQNDPNEARAQLITLRRSVLKLTGDVLN
                     DDPRDLQLQPIAGRLKCAHVNHVEALCDAEDVLVWSVAVTPAIEKLSVWELDGKHSWK
                     SLPDIHSRANNPTSRMMRFAQLSTVKSFSPN"
     gene            34067..34633
                     /gene="yieF"
                     /locus_tag="RHX21_001484"
                     /gene_synonym="chrR"
     CDS             34067..34633
                     /gene="yieF"
                     /locus_tag="RHX21_001484"
                     /gene_synonym="chrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I chromate reductase YieF"
                     /protein_id="HDV1986694.1"
                     /translation="MSEKLQVVTLLGSLRKGSFNGMVARTLPKIAPASMEVNALPSIA
                     DIPLYDADVQQEEGFPATVEALAEQIRQADGVVIVTPEYNYSVPGGLKNAIDWLSRLP
                     DQPLAGKPVLIQTSSMGVIGGARCQYHLRQILVFLDAMVMNKPEFMGGVIQNKVDPQT
                     GEVIDQGTLDHLTGQLTAFGEFIQRVKI"
     gene            complement(34687..36024)
                     /gene="adeP"
                     /locus_tag="RHX21_001485"
     CDS             complement(34687..36024)
                     /gene="adeP"
                     /locus_tag="RHX21_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine permease AdeP"
                     /protein_id="HDV1986695.1"
                     /translation="MSQQHTTQASGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVY
                     IVFVNPQILGVAGMDTSAVFVTTCLIAAFGSIMMGLFANLPVALAPAMGLNAFFAFVV
                     VQAMGLPWQVGMGAIFWGAIGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMG
                     LKNAGVIVANPETLVSIGNLTSHSVLLGILGFFIIAILASRNIHAAVLVSIVVTTLLG
                     WMLGDVHYNGIVSAPPSVMTVVGHVDLAESFNLGLAGVIFSFMLVNLFDSSGTLIGVT
                     DKAGLADEKGKFPRMKQALYVDSISSVTGSFIGTSSVTAYIESSSGVSVGGRTGLTAV
                     VVGLLFLLVIFLSPLAGMVPGYAAAGALIYVGVLMTSSLARVNWQDLTESVPAFITAV
                     MMPFSFSITEGIALGFISYCVMKIGTGRLRDLSPCVIIVALLFILKIVFIDAH"
     gene            36191..36856
                     /gene="yieH"
                     /locus_tag="RHX21_001486"
     CDS             36191..36856
                     /gene="yieH"
                     /locus_tag="RHX21_001486"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate phosphatase"
                     /protein_id="HDV1986696.1"
                     /translation="MSQIEAVFFDCDGTLVDSEVICSRAYVTMFQEFGITLDPEEVFK
                     RFKGVKLYEIIDIVSLEHGVTLAKTEAEHVYRAEVARLFDSELEAIEGAGALLSAITA
                     PMCVVSNGPNNKMQHSMGKLNMLHYFPDKLFSGYDIQRWKPDPALMFHAAKAMNVNVE
                     NCILVDDSVAGAQSGIDAGMEVFYFCADPHNKPIVHPKVTTFTHLSQLPELWKARGWD
                     ITA"
     gene            36923..37396
                     /locus_tag="RHX21_001487"
     CDS             36923..37396
                     /locus_tag="RHX21_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein CbrB"
                     /protein_id="HDV1986697.1"
                     /translation="MSVSRRVIHHGLYFAVLGPLIGVLFLVLYIFFAKEPLVLLVIIQ
                     VLPLFLLLSITTGAIPALLTGVMVACLPEKIGSQKNYRCLAGGIGGVVITEIYCAVIV
                     HIKGMASSELFENILSGDSLVVRIIPALLAGVVMSRIITRLPGLDISCPETDSLS"
     gene            37445..38032
                     /locus_tag="RHX21_001488"
                     /pseudo
     CDS             37445..38032
                     /locus_tag="RHX21_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418173.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CbrC family protein"
     gene            complement(38094..38816)
                     /locus_tag="RHX21_001489"
     CDS             complement(38094..38816)
                     /locus_tag="RHX21_001489"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDV1986698.1"
                     /translation="MKLIITEDYQEMSRVAAHHLLGYMSKTRRVNLAITAGSTPKGMY
                     EYLTTLVKGKPWYDNCYFYNFDEIPFRGKEGEGVTITNLRNLFFTPAGIKEENIQKLT
                     IDNYREHDQKLAREGGLDLVVLGLGADGHFCGNLPNTTHFHEQTVEFPIQGEMVDIVA
                     HGELGGDFSLVPDSYVTMGPKSIMAAKNLLIIVSGASKAQALKNVLQGPVTEDVPASV
                     LQLHPSLMVIADKAAAAELALG"
     gene            complement(38831..40000)
                     /locus_tag="RHX21_001490"
     CDS             complement(38831..40000)
                     /locus_tag="RHX21_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709476.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HDV1986699.1"
                     /translation="MNIKIAALTLAIASGISAQWAIAADMPASPAPTIPVKQYVTQVN
                     ADNSVTFRYFAPGAKNVSVVVGVPVPDNIHPMTKDEAGVWSWRTPILKGNLYEYFFNV
                     DGVRSIDTGTAMTKPQRQVNSSMILVPGSYLDTRSVAHGDLIAITYHSNALQSERQMY
                     VWTPPGYTGMGEPLPVLYFYHGFGDTGRSAIDQGRIPQIMDNLLAEGKIKPMLVVIPD
                     TETDAKGIIPEDFVPQERRKVFYPLNAKAADRELMNDIIPLISKRFNVRKDADGRALA
                     GLSQGGYQALVSGMNHLESFGWLATFSGVTTTTVPDEGVAARLNDPAAINQQLRNFTV
                     VVGDKDVVTGKDIAGLKTELEQKKIKFDYQEYPGLNHEMDVWRPAYAAFVQKLFK"
     gene            complement(40027..41643)
                     /gene="bglH"
                     /locus_tag="RHX21_001491"
     CDS             complement(40027..41643)
                     /gene="bglH"
                     /locus_tag="RHX21_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate-specific porin BglH"
                     /protein_id="HDV1986700.1"
                     /translation="MFRRNLITSAILLMAPLAFSAQSLAESLTVEQRLELLEKALRET
                     QSELKKYKDEEKKKYTPATVNRSVSTNDQGYAANPFPTSSAAKPDAVLVKNEEKNASE
                     TGSIYSSMTLKDFSKFVKDEIGFSYNGYYRSGWGTASHGSPKSWAIGSLGRFGNEYSG
                     WFDLQLKQRVYNENGKRVDAVVMMDGNVGQQYSTGWFGDNAGGENYMQFSDMYVTTKG
                     FLPFAPEADFWVGKHGAPKIEIQMLDWKTQRTDAAAGVGLENWKVGPGKIDIALVRED
                     VDDYDRSLQNKQQINTNTIDLRYKDIPLWDKATLMVSGRYVTANESASEKDNQDNNGY
                     YDWKDTWMFGTSLTQKFDKGGFNEFSFLVANNSIASNFGRYAGASPFTTFNGRYYGDH
                     TGGTAVRLTSQGEAYIGDHFIVANAIVYSFGNDIYSYETGAHSDFESIRAVVRPAYIW
                     DQYNQTGVELGYFTQQNKDANSNKFNESGYKTTLFHTFKVNTSMLTSRPEIRFYATYI
                     KALENELDGFTFEDNKDDQFAVGAQAEIWW"
     gene            complement(41712..43124)
                     /gene="bglB"
                     /locus_tag="RHX21_001492"
     CDS             complement(41712..43124)
                     /gene="bglB"
                     /locus_tag="RHX21_001492"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase BglB"
                     /protein_id="HDV1986701.1"
                     /translation="MKAFPETFLWGGATAANQVEGAWQEDGKGISTSDLQPHGVMGKM
                     EPRILGKENIKDVAIDFYHRYPEDIALFAEMGFTCLRISIAWARIFPQGDEVEPNEAG
                     LAFYDRLFDEMAQAGIKPLVTLSHYEMPYGLVKNYGGWANRAVIDHFEHYARTVFTRY
                     QHKVALWLTFNEINMSLHAPFTGVGLAEESGEAEVYQAIHHQLVASARAVKACHSLLP
                     EAKIGNMLLGGLVYPLTCQPQDMLQAMEENRRWMFFGDVQARGQYPGYMQRFFRDHNI
                     TIEMTESDAEDLKHTVDFISFSYYMTGCVSHDESINKNAQGNILNMIPNPHLKSSEWG
                     WQIDPVGLRVLLNTLWDRYQKPLFIVENGLGAKDSVEADGSIQDDYRIAYLNDHLVQV
                     NEAIADGVDIMGYTSWGPIDLVSASHSQMSKRYGFIYVDRDDNGEGSLTRTRKKSFGW
                     YAEVIKTRGLSLKKITIKAP"
     gene            complement(43143..45020)
                     /gene="bglF"
                     /locus_tag="RHX21_001493"
     CDS             complement(43143..45020)
                     /gene="bglF"
                     /locus_tag="RHX21_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIABC"
                     /protein_id="HDV1986702.1"
                     /translation="MTELARKIVAGVGGADNIVSLMHCATRLRFKLKDESKAQAEVLK
                     KTPGIIMVVESGGQFQVVIGNHVADVFLAVNSVAGLDEKAQQAPENDDKGNLLNRFVY
                     VISGIFTPLIGLMAATGILKGMLALALTFQWTTEQSGTYLILFSASDALFWFFPIILG
                     YTAGKRFGGNPFTAMVIGGALVHPLILTAFENGQKADALGLDFLGIPVTLLNYSSSVI
                     PIIFSAWLCSILERRLNAWLPSAIKNFFTPLLCLMVITPVTFLLVGPLSTWISELIAA
                     GYLWLYQAVPAFAGAVMGGFWQIFVMFGLHWGLVPLCINNFTVLGYDTMIPLLMPAIM
                     AQVGAALGVFLCERDAQKKVVAGSAALTSLFGITEPAVYGVNLPRKYPFVIACISGAL
                     GATIIGYAQTKVYSFGLPSIFTFMQTIPSTGIDFTVWASVIGGVIAIGCAFVGTVMLH
                     FITAKRQPAQGAPQEKTPEVITPPEQGGICSPMTGEIVPLIHVADTTFASGLLGKGIA
                     ILPSVGEVRSPVAGRIASLFATLHAIGIESDDGVEILIHVGIDTVKLDGKFFSAHVNV
                     GDKVNTGDRLISFDIPAIREAGFDLTTPVLISNSDDFTDVLPHGTAQISAGEPLLSII
                     R"
     gene            complement(45154..45990)
                     /gene="bglG"
                     /locus_tag="RHX21_001494"
     CDS             complement(45154..45990)
                     /gene="bglG"
                     /locus_tag="RHX21_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional antiterminator BglG"
                     /protein_id="HDV1986703.1"
                     /translation="MNMQITKILNNNVVVVIDDQQREKVVMGRGIGFQKRAGERINSS
                     GIEKEYALSSHELNGRLSELLSHIPLEVMATCDRIISLAQERLGKLQDSIYISLTDHC
                     QFAIKRFQQNVLLPNPLLWDIQRLYPKEFQLGEEALTIIDKRLGVQLPKDEVGFIAMH
                     LVSAQMSGNMEDVAGVTQLMREMLQLIKFQFSLNYQEESLSYQRLVTHLKFLSWRILE
                     HASINDSDESLQQAVKQNYPQAWQCAERIAIFIGLQYQRKISPAEIMFLAINIERVRK
                     EH"
BASE COUNT        11303 a        12069 c        11457 g        11348 t
ORIGIN      
        1 gtaggttact gcgacgagat cgaccagata ttgcagtcag gtattactac aaaggcgttt
       61 tgtggagtcc tggctatttt gccaatagct gcggaggtgc gccaatatcc gtcatccgcc
      121 aatacattga acaacagcaa acacctggtt aggtggaaaa ccgcgcctta tatccccgcc
      181 ctgaaggacg gggatataag gcgcaccgga taaatttggt tatgcgccgt cagccgtgct
      241 aaagaatacg gaccagcacc caacagatgc cagtccacac aattaacgta actctggcca
      301 gtacgctttg ttggccttca gcaattcatc cagaatagct ttggcgaccg aggcgctcgg
      361 taccgttttc gacaacgtaa tcgcctgcca caggtgctga tatgaacgct gttcccaggc
      421 gtccacgacc agtttttcca ccgccacttg ctgactcatt aaccctttct gaaactgcgg
      481 gatatcgccg accaccagtg gttctggtcc gttgtgccca accagacacg ggatctcgac
      541 catcgcttca tcatcaaagt tatgaattgc cccgttgtta ggcacaatca gcaacatccg
      601 ctcctgagtg ttgaaggcaa ttgccgccgc cagatcgacg atgtatgacg catgttcgtc
      661 aatttccagc ttgcccgccg ctgaatttcc tgccgccgta atggcgcggc aagcatcgaa
      721 aacctgtttc tcgcgatgtt ccatcacctc attcgcgcgg gtatgttcag ggttggaatg
      781 ctgaacgacg taatccggga agagataata tttcagatag gtgtttggta atgtatccgg
      841 ggccagtgcc tggacatccc gcgcttttgc ataggtgtcg ttccagctcg cttcagtatg
      901 cgtatcttgc tgcggtggaa cataaccatg cttagagaca tattgccgca gctggggcat
      961 caggtcgttg ccctgcaaat cttcaattga tgtccaccag ccaaagtggt tcaggccgta
     1021 gtagcgcacg cgcatctgtt tgcgatcttg cagcccaaca atttgcgcca tccggctttc
     1081 aataccgatt ggcatgtcac agatgttgag gattttcgca ttcgggcgca gacgacgcgt
     1141 ggcttctgcg acaatggctg ccgggttgga gtagttgagc atccaggcat ttggtgaata
     1201 tttttccata taatccacca gttccaggac gccgccaatg gaacgcatgc cgtacgctat
     1261 tccgccgggt ccgcaagttt cctgaccaac aacgccgtgg cgcagcggga ttttttcatc
     1321 cagttcgcgc atcgggtatt tgccgacgcg gatgtgcgcc atgacaaaat caacgtcgct
     1381 gaatgccact tcaggatcgg tggtgtaact aaacgcaatg tccggcgctt tttctttaag
     1441 gatgacttta caggcttcgg caatcacttc ctgccgcgca ccatcgttat cataaaattt
     1501 cagtgcacga agcgggaaac ggtcctgatt cgccaggagc atcaacacga tgcctggcgt
     1561 aaaggtgctt ccaccgcctg cgacaaccac tgagaatttg gtcattatac tgcctccgta
     1621 atggcaacat tttctgctga ttgatgagaa ttaattaagc tatcgagctg ttcacgcagc
     1681 tgagatacat gcagaccaat gatcacctga atggcatcgc cactacggaa gacgccgtgc
     1741 gctcccagct ttttaaagac ttcgtcatcc agcgtttgtg acatgtcatg cagtgcaata
     1801 cgtagacgcg tcgcgcaatt gttgatgctg gagatattgc cgaccccgcc cagggcttgc
     1861 aggataccgg cagcctgatc caactctttt tttggctctg cagcggtggt ttggcctcgc
     1921 gaggctttat attcggcttt tgagtagagt ttcacttccg catcttcacg tcccggcgta
     1981 cacatgttga actgcagtat cagggtgcgg aaaaccacga agtacagcag ggtaaagcac
     2041 aacccaatgg cgatttgggt cagcatcata tccgcgtggt tgctgaacat cgggatccag
     2101 ttttgcggta aaacctggtc aatcagacct ccgcccatgt tgcccaccac accaaagaga
     2161 tacattacgg tcgacattga ggccgcaagc acagcgtgta ccgcaaacag caacggtgaa
     2221 atgaacagga aggtaaattc cagcggttcg gtaattccca ccagcatggc ggttaaggtt
     2281 gcggggatca gcaagcccgc cacttttacc cgattttccg gtgcggcagt gaagtacatc
     2341 gctaaagaaa tgcccacggc accaaagatt tttgagttac cgtgcagggc aaaaccgcct
     2401 tccgggaaca acgatttcag cggctcggcg ctcagactga actcttgcag atgctgcgcc
     2461 cagtacatct gaatgccgcc ttcaacagct gccggaccaa agataaacgg tccgtagatg
     2521 aagtggtgta aaccggttgg gatcagaata cgttcgagga aggtgtaaac ccacacccca
     2581 agcgcacccg ccgaacgcag gaacgcttgc agagattcaa tccccatttg tacttttggc
     2641 cagccgagca atgtcagcca ggcacagggg atcatcacca ggaaggcgat aatcaccaca
     2701 taagacgtcc cctggaaaat gccgagaaac accggcagtt ttttatcgaa cagacggtta
     2761 tgcagcgccg tcacaatgcc ggaaatgata attgcgccga taatgctggt atcgagggtt
     2821 ttaatcccgg ccatcattgt cagaccgcta cctgccaccg cgtcctgagt gaaatcgacg
     2881 ccgaagtaac ttccccaggt cattcccatc gcattaatga aatagttcca ggtcaggaaa
     2941 ctcaccatca ccgccagaca agcacgcccc tgcgcttgct tagcaaggcc aatgggtaaa
     3001 ccgacagcaa aaatcagcgg catattacgg aataccgtcc aaccgccctc ttcaataatg
     3061 tgtacgattt gcgcgaataa actgttcgga tcggtcagtg attccccgac aaacatcggg
     3121 ttttgcaaca agatggcaag acccaccaca atcccggcga agggaaacag cagcactggc
     3181 gtgaacatcg cgccgccaaa gcgttgaatt tgactgagca tttccacatc ctcttttctc
     3241 aattctgtaa gtaggaagcc tgattggtta tgcggcaggc ctggagcgag gataggaaga
     3301 tgcgatcggc agaacatgac gacccaatgg gattcgtgat cgctttcatg cttttcgttg
     3361 ggcggtagag atctacgttt tcgcgaaaaa gtagacctct gtgagcacag gtacacagca
     3421 tcgaacacat ctttaaaaaa aagatgtttt ttcaatcgat taagcagaac ttgtgtgcgc
     3481 attacccgag cttgcaggca aaaaagagat ctagagatga tctacaaaag cattgcggag
     3541 cggttaagaa ttcgacttaa ctccgcagat ttcacgctaa acagccttct tcccggtgaa
     3601 aaaaagctgg cggaagagtt tgcggtatcg cggatgacca tccgtaaagc cattgacctg
     3661 ctggtagcgt gggggctggt ggtccgccgc cacggtagtg gcacttacct ggtgcgcaaa
     3721 gatgtactgc atcaaaccgc cagtctgacc gggctggtgg aggtgttaaa acggcaggga
     3781 aaaacggtca ccagccaggt gctgattttt gaaatcatgc ctgcgcctcc ggccattgcc
     3841 agccagttac ggattcaaat caacgagcag atctacttct cccgtcgcgt tcgttttgtg
     3901 gaagggaaac cgctgatgct ggaagacagc tatatgccgg taaaactgtt ccgtaatctt
     3961 tcgctgcaac atctggaagg gtcgaagttt gaatatattg aacaagagtg cgggattttg
     4021 attggcggta attatgaaag cctgacgcca gtgctcgccg atagactgct ggcgcggcaa
     4081 atgaaggtag cggaacacac gccactgctg cggatcacct cgttgtcata tagcgagagc
     4141 ggggagtttt tgaattattc agtgatgttc agaaatgcca gcgaatacca ggtggagtac
     4201 catttacggc gactccaccc ggaaaagagt taaccgatac tccagaagag caccgccagt
     4261 aattgggggg tgataatgcg caggaacatt accaacggat agacagtggc gtaagagagc
     4321 gccgccgcac cgctggttgg atgaagatta ttagcaaacg ccagcgccgg aggatcggtc
     4381 atggagcctg ccagcatccc gcacatggtc aggtaattca ttttggctaa catccgcgcc
     4441 agaatgccaa cagtaatcag cggaacggcg gtgatcaggg caccataacc aatccagctt
     4501 agcccttcgc cattgaccag ggtattcaca aaatccccac cagatttcag accaacgacc
     4561 gagaggaaca gcacgatccc cagctcccgc agcgcgaggt tggcgcttgg cggcataaac
     4621 cagtacagct tgccgatact gccgatacgc ccgaggatca acgccataat cagcggtccg
     4681 cccgccagcc ccagtttcaa cgcggccggg aatcctggca caaagacggg aatagaacct
     4741 aacaatacgc ctagcccgat gccaataaac actggcagca tctgaacctg ttgcagtttt
     4801 tgctgcgcat tccccagcac attggcaacg gcatcaattg cggacggacg ccccaccaga
     4861 ttgaggatat cgccgaactg caggctgata tcgccactgg cgaccagttc gaccccggca
     4921 cggttcaggc gcgagataac aacgtcatag cgttctttaa agtgcaggtc gcgaatacgt
     4981 tttccgagca cgttttcatt ggtgaccacc acacgctcga cgcgcaaatc agtgcctttc
     5041 gtggacagcg aagtatcgac ctcctgacca atcaccagtt gcgcattatg taaatccgct
     5101 ggctgaccca ccagatgcag caaatcgccc agttggataa tggtatctgg cgaaggaact
     5161 tttagggttt cttcgcgttt cagacgcgag cagataattt tgtcgccgtt gagaatcggt
     5221 acatctttaa tggctaaatc atgcaggtta gggttctcaa cgcgaatatt gatagtcttg
     5281 atcagcgcgc cgccattggt gcgtgaagac tcgtgctgct gagcttctgt ctcgacattg
     5341 acgcggaaaa taacccgcaa catccacatg gtgaacaaaa tcccgcaaat gccgaatgga
     5401 tacgccatcg cgtaactcat ccccatctga tcgaccattt ccattggtgt acccaggtcg
     5461 cgcaaaatct gctgccctgc ccccagcgct ggcgtattgg taaccgcacc ggagaaaatc
     5521 cccagcacta ccggcagtgg aatatcaaac agtttatgca ggatggcggt aaccagacca
     5581 ccgatgatga cgatcagaac agcaaacagg ttgaggcgta atccggagac gcgcaatgag
     5641 gcaaagaagc ccggccctac ctgaatcccg atagtataaa cgaacaggat caggccaaat
     5701 tcctgaataa catgcagcat atcgctactt aatgtcatcc ccgcctgaga aacaaaatgg
     5761 ccgacgatga tcccaccaaa cagcacgccg ccaataccta atcctatgcc gcgaaatttg
     5821 acgttgccga taaacaaacc gacgactgcc accaaagcca gaatactgac cgttaatgct
     5881 atatcactca tcgtccattt ctcttgagat aacattttaa ttgctacgga ttatggctga
     5941 atcggtgaag cagatttgcc ttatagcgca cattatcacg ggaaagaacg tgccgaaata
     6001 tcttaaacag tcgaaattta acgcattgtt gagtaagtaa gacaaaaaaa gccccaccag
     6061 aatggcgggg caaagagaat agctagttag ctatttaacg cgggacgttc gctgatagcg
     6121 atacgctgcg ctgcgatggg ttcaggctca ttacgaatta aatcaatatg cagtaaaccg
     6181 tttacgaagg ttgcgccaga gacttccata ttttcagcca gcgtaaagct caggctaaat
     6241 ggctgattca taagcccttg atgcagccat tttttctctt cttttggctg ctccggcgtg
     6301 ccttttacgc tcaggcgcgt accttccagt tgaatctcta aatcttcctg acggaaacct
     6361 gccagcgcaa gggtaatgcg gtagtggtta tcgtcgcttt tctcaatgtt gtacggcggg
     6421 aagctctggc tttcaccggc gttttgcagt gcgttggcca gtttgtcaaa accgatccat
     6481 tgacgcatca gtggggataa atcgaagtta cgcatagtca tttctccttc taagaagcga
     6541 gtaagtacct gcaaatccga agattcgcat atgctccctg acggcgagca tggagatgtc
     6601 aggccgcgcc aggcggcctt agggaattag ttgatttcga tacggcgcgg ttttttcgct
     6661 tccggaatca cgcgttcgag atcgatatac agcaaaccat ttaccaggtt agcaccacga
     6721 acatgaatgt tctcagctaa ctggaatttg cgttcaaagt tgcgttcagc gatgccctgg
     6781 tacagatagg tgcgctcttt ttgttcgtcg gcgtgagcac ctttcaccac cagcagatta
     6841 tcctgggcgg taatttccag ttcgctctca gcaaaaccag ccacagcgat agcaatgcgg
     6901 taatggtttt cgtctaccag ttcaacgtta tacggagggt agccgccatt actctggctc
     6961 tggttgtttt ctaagtggtt aaacaaacgg tcaaatccaa tagcagaacg gtaaagcggg
     7021 gataaatcaa agttacgcat aatcaatagc tcctgaaatc agcgagaatg taagaccttc
     7081 cacaatggac aggtcaggta gccagaacac ccatcaggcg cgtcctcatc ggctacgatg
     7141 taaaaatggg tctggaaatg aacttttcaa gccttatcag cggacttttt tttgcagttt
     7201 atggtctatt gcatagactg agggggcagc acgaaacgtt aaagtgcgat agccgccaca
     7261 gtgcgacgta atgatgatgt tattttcagc aagggatcgc tataactcat caggccaaca
     7321 cccacgatca acagatgaat ttattatgat aagaaatgtg ttgttagcgt tcatgatatg
     7381 cagcggaatg acattactcg gaggatgctc cagcgtgatg tcccataccg gagggaaaga
     7441 aggaacgtat cccggcaccc gcgccagcgc aaccatgatt ggcgacgatg aaaccaactg
     7501 gggcactaag tcgctggcga ttctcgatat gccgtttacc gctgtgatgg acacgctttt
     7561 actgccgtgg gatgtgttcc gcaaagacag ctcggtgcgc tcgcgcgttg aaaaaagcga
     7621 agccaacgcg caagccacca atgcggttat tccaccggcc agaatgcctg ataactgatt
     7681 tagcgatcag tttcggtgat ccacagctgg ccgccttcca tccacgccag ccactgacca
     7741 tccggcgaga agaccacggc gtccgcagaa ggtgaattgg cgtggtgttc ggttaaatac
     7801 tcaacctcgc cgctttgcgc atgggcacaa gcaattcgat tatccagcac aaagcccaac
     7861 cattctcctg acggatgcca gttaaatgca gactgaatat ccgttttgtt atgggttaac
     7921 tggcgcggct cgccgccctg tggcgagata agccacagtt gcacaatgcc gttatcatca
     7981 cgcattaaaa acgcgatttg cgtaccctgc ggattacagc gcacccagtg gcgcgggacg
     8041 ttgactaacc ccggataagc ccgatggtgg gtaaaggtta aacgtcgctg cacgacgccg
     8101 cgcggtggcg cgggcagggt ggtttccgtt ccacttaacg gcgcatcacc tgccgctttc
     8161 cagccagctt catcttgcgg taactcaacg ataaacagct ccggcacttt ctcgcccttt
     8221 ggcgaaagtg tgtcgccaat aaacgccagc gcgtgatttc ctacccatcc ttcttcataa
     8281 gcacgattga tttcatcgct gccaggctgc ggcgtgggcg tggttttact caccagcacg
     8341 caccagtggc taccgctgta ttcacgcgga tgctgctttt gtacgttgac cgggccaaac
     8401 ggcgcagcaa caccgacgtt tcgcaaatcc agcgccggat cgagttcatg cattacatgg
     8461 tcgttatagg taaagctcac cctttcaccg ttcgggctaa agacatgcac atggctgcca
     8521 ccgcgcagcg ctcctggcgt atacggcgcg gtaatatcca ttgcatcgag attgctcacc
     8581 ttgccgcctt cagcaatgac tccgcgtcga tgatggaagt cgtaatgcca tgtttcatca
     8641 ggattttccg ggccatggat gaaaacatat ttctctgact tcggatgaac ggtcaccacg
     8701 ccgacgtgtg cgccctgtga cgcgcgatag ataacctcga cctcgcctgt atggatattc
     8761 acacgctcaa tggtctcgcc ggtaaacgac gccccagaag gacgcacgtc aaataccagc
     8821 cactggctgt cgggcgtcca ggtattggta ttggtgagca ggtgattacg gggagcaaag
     8881 gttatctgtt tcatggcgcg gtcctgatac aaaacggttc ccgccatcat acttcacaag
     8941 gacttcactt tcagacaata gtcttttgcc atcgtgatga atgtgagtga aaagatggaa
     9001 catttcgacg tggcgattat tggcctcggc ccggcaggat cggcgttggc gcgaaaatta
     9061 gcaggcaaaa tgcaggtgat cgcgctggat aaaaagcacc agtgtggtac tgaaggtttc
     9121 agcaaacctt gtggcggtct gctggcaccg gacgcgcagc gatcttttat tcgcgatggg
     9181 ctgacgcttc ctgtcgatgt gatcgctaat ccgcagattt tcagcgtcaa aaccgtcgac
     9241 gtcgccgcat cgctcacgcg taactaccag cgaagctata tcaatattaa tcgccatgct
     9301 ttcgacttgt ggatgaaatc gctgatcccc gccagcgttg aggtttatca cgacagcctg
     9361 tgtcgaaaaa tctggcgtga ggatgataaa tggcatgtca tttttcgtgc agacggctgg
     9421 gagcagcata ttaccgcccg ctatctggtc ggtgccgatg gtgccaactc gatggtgcgg
     9481 cgacatctct acccggatca tcaaatccgt aaatatgtcg caatccagca gtggttcgca
     9541 gagaaacatc cggtgccgtt ctactcctgc atctttgata atgcgataac tgactgttat
     9601 tcatggagta tcagcaaaga cggttatttt atctttggcg gtgcctatcc aatgaaagac
     9661 ggtcagacgc gtttcacgac gctgaaagag aaaatgagcg cctttcagtt ccagtttggt
     9721 aagacggtga aaagcgaaaa atgcacggtg ctgtttccct cgcgctggca ggattttgtc
     9781 tgcggtaagg acaacgcctt tctgattggt gaagcggcgg gatttatcag cgccagctcg
     9841 ctggagggga ttagctatgc gctggatagc gcagacattc tgcgttcggt gttactgaag
     9901 cagccagaga agctcaatac cgcttactgg cgcgccaccc gcaaactgcg tttaaaactc
     9961 ttcggcaaga tagtaaaaag ccgatgcctg accgcaccgg ctttaagaaa gtggattatg
    10021 cgcagtggtg tggcacatat tccacagttg aaggattagc caacgcgctt cacatcgccc
    10081 accagcagga tataagagag cgcgccaatc aacgcgacgg cggagatata aaccagtgca
    10141 ggtgcgaaac cgtaaccctg cgccaggtac cccaccacca gcggaacggt gatgccgccc
    10201 agaccaccgg cgaagttaaa cacgccgccg gttaaaccaa tcaggcgcat cggtgccaga
    10261 gagcaggacg ccgacaaacg ccgcgaggaa tggcaccgtg gtcataaagc ctgctttcag
    10321 cgccgtgatt cctttttcct gggttaaata gttcgggaac caggttaaga aaaaccacag
    10381 tgtagaagcc accgcaaatt gcccaagata aacgccgatc agtttacgat ggaacaccag
    10441 tttccagtct ttggctgtta acggctgacg cgcctctttc ttcaccggcg catcaccatc
    10501 caccagaccg ccgccatcac gaatgtaatc cagttcagct ttgctgatac ctttggtcag
    10561 gcgcggcggc tgataaacct taaaccaaat cagcgaccag ataatgccga taccaccagt
    10621 gacaatgaac acccagtgcc agctcaacat ctcctgaatc cagatcagca gcggcgtcag
    10681 aaacgccaga ccgacaaact gaccagacgt ataaaaacca acggcagaag cgcgttcatg
    10741 ttccgggaac cagctggtca ccatccggtt attggtcggg aaagcaggcg cttcgaaaat
    10801 accggttatc gcgcgcagac caattaatga cattaagccc gtggcaaagc cctggaataa
    10861 agtcgccact gaccagccaa atatcgcaat aaaataagtc acgcgagaac ctacgcgatc
    10921 taaaaaccaa ccgccgggga tctgacatag cgtataaagc caggcgaagg ccgaaaatac
    10981 atagcccatt tccgctttgg taatgccgaa ctcttcctga atatgggcgg aagccacggc
    11041 caggttggcg cggtcgacat aacaaatgac taccgtaata aagatcatca ccagcgtcag
    11101 ataacgccga cgccccggct ttgctgcatt aacgggaata tccatagcga gctttctcca
    11161 gattttgggc atagcgaagc cgctcaccat gccctgtaat ttacagaggg ttatattttt
    11221 gtattgctgt tttagtgccc gatgaggggc ttacgtggca ggaattacca ctctgctacg
    11281 ctgttatctt catgacgcca gagcggatta cgccagtccg gggcattttt actgaactca
    11341 atcactttag cttcgtcgat ttccacgcct aagcccggtt tcgttaacgg tttaaagaag
    11401 ccgccgacca tgctgaagtc ttctttgttt ttcacaaagt cgagtaactc cgcgcctttg
    11461 ttgtaatgaa ttcccatact ttgttcctga agtacggcgt tataggaaac aaagtcgata
    11521 tgcaggcaag ccgccagtgc aatcggtccg agcggacagt gcggcgcaag ggtcacgtca
    11581 taggcttctg ccattccggc gattttgtag cattcggtaa taccgcccgc gtgggagaga
    11641 tccggttgca gaatcgaaat accacctgcc tccagcacgc gtttaaaatc gaagcgtgag
    11701 aacatgcgtt cacccgccgc cagtggaata tgcgtttgtg ccgccagttt cgggtagtat
    11761 tcggcttgtt ccgccagcac cggctcctca ataaacagcg ggcgatacgg ctccagttct
    11821 ttaatcagca ctttcgccat cggcgcgctg acgcgaccgt ggaaatcaag accaaactca
    11881 atctgattgc caaaagcttc acgaatttgt gccacggtgt taaccgccgc atctaccgcg
    11941 cgggagttat caattggccc cagttcttca caaccgttca gtttgaaggt atcgaagccg
    12001 atttcgcgta gcgttttaat gccgtcgata acatccgccg gacgatcgcc gccaacccaa
    12061 ctgtaggctt taattttgtc gcgaaccagg ccgcccatca gttgccagac cggcgcattc
    12121 agcactttac ctttgatatc ccataacgcc tggtcaatcc cggcgatggc gctcatcagg
    12181 atcggaccgc cgcgatagaa tccggcgcga tacatcactt gccataagtc attgatgcgc
    12241 gatggatcct gaccaatcaa atagtcaccc agctcgtgaa ctgccgcttc caccgtacgg
    12301 gcgcggcctt cgatcacggg ctcgccccaa ccgaccacgc cttcatcggt ttcaattttc
    12361 aggaacatcc agcggggagg taaacgatac gtggtaattt tggtgatttt cattgcactg
    12421 cctctcgata cgccttaaca aatgctgctg cctgctgcgc ggtgcgctct acggattgcc
    12481 cggcgcgata gagatcgctg cctaagcccg cccctgcaca acctgcgtct atccactgcg
    12541 ccaggttttc tggcgtcacg ccgccaacgg caaagactgc gatgtccgat ggcaataccg
    12601 cttttaacgc tttgatgtat tgcggaccaa aagccgatga cggaaatatt ttcagcgcct
    12661 gcgcgcccgc ttcgagcgcg gtaaaggctt cggtcgccgt cgcgcagccg gggcagacgg
    12721 tcatgccgta gcccaccgca cggcggatca cttcactatg gatattgggc gtaacgatga
    12781 gctgacagcc catcctggcg agcgcatcga cctgttcagg tttcagtacc gtacctgcgc
    12841 caatcaacgc cttgtcgccg tacgcatcaa cgatggcggg aatgctttgc tcccattgtg
    12901 gggaattcag cgggatttca accgcgtcga acccggcgtc aatcaccgcg ccaacatgcg
    12961 ccagcgcctc gtcgggcgta ataccgcgca aaatggcgat cagcgggagt ttagtttgcc
    13021 actgcatgag cgatgctcct tataccagcc tgaaatgccg tgtcgcccgc caccgccgtc
    13081 acgtcgcaac ccatcgcctg aaaggcttgc tggtagcgcg cggtcagcga tgttccggcg
    13141 acaagggtga tggcgtgttg atgggccaca tagtcgcgca tactggcgac ctctgcgcca
    13201 atcaacaaac cagagagaaa ttcgctgacc tgttcgcggg gaagtgttcc cagcacatgc
    13261 gaggcgcgaa cttcaaaaag ctgcggcaat atggcgggcg tattaagacc acgctcaagg
    13321 ccagctgtga aggcatcggc agagttttcc tgcggcggca aacctgcgcc aatcaatgag
    13381 tgatttaaca gtaaatgatg taattcaccg gtcatcacgg tgcgaaaatc gttgatttgc
    13441 tggctatcgg cctgcaccca tttgcaatgg gttccgggca tgacataaag agaggaagga
    13501 gccagagctc gcgcgccgat caattgtgtt tcttcgccgc gcatcacatt gtggttatcg
    13561 tcatgagaga cacataatcc gggaataatc cagatattgt cgccaactga cgttaattgt
    13621 tcgccaatag acgaaaaaca ggcaggaaca gataaatacg gtgcaacttt ccagccgacg
    13681 ttgctgccaa ccattcctgc cattaccact ggcgttttct cttcacgcca gtcggtcgtg
    13741 acttctgcta acaccgcagc cggagatttt ccgttcaggc gcgtgacgcc tgcttctgat
    13801 tgcctgctct ccaggcagtg gtcgctctga taaagccagg cgcgcagatt ggtcgatccc
    13861 cagtcaattg cgatgtagcg agctgtcatg tgatttcctt taaccttcgt gtcgagctgg
    13921 cgatcatggt aagcgccgcc tgctctgccg catcgccgtc ctgatgtcgt atcgcatcga
    13981 acagcgcctt atgttcctgg agcgtttgcg gcatgttggc ctcatcgccc atccaggttc
    14041 gttcaaaaac cgcccgctgc agcgaactga tcgcaatgct aagttgctgt aacaccgggt
    14101 tatgcaccga ctgcagcacc gcctcgtggt agcgaatatc cgcttcgtta aacgcttcgc
    14161 ggtcctgatt gttggcaatc atctcgttca gcgccgattc aatctgcgcc agatcgctgg
    14221 aagtcgcgcg ctctgctgcc caacgggcaa tcgccggttc caccagattt cgcacttcgc
    14281 tcatggcact gataagccgt gggtcgtagt cattttccag cacccattgc agtacgtcag
    14341 tgtcgaggta attccactgg ttacgcggtg ccacaaacgc cccgcgataa cgtttcattt
    14401 caatcagccg cttcgccatc agcgaacgga acacctcacg gatgatgttg cgcgaggttg
    14461 caaactcctc acagagttcc gcctcagccg gaagcggcga gcctggcacg tatttgccgt
    14521 gaacgatctg tttacccagc gtaatgacaa tgcgatcggt tttattgaga gtcatggaga
    14581 gtccttgtgc tctgtatgtt cttctctact ttaccccgat cgatgcataa cgcggcaact
    14641 ttgtagtacc agcgtgatga cgttcgcgtt tgccgtgcgt gtaatgtagt acaaacttat
    14701 attgttgtac tacaatttag atcacaaaaa gaacaatgca taaaaaaatg acatgcgtcg
    14761 ggcagaaatc tgaaaaggga tatcaggcgc taaacaggag ggaaagaaga gtatgctttc
    14821 aacggcttag ctactcgttt aaaggattaa tcatgaagtt gaattttaag ggatttttta
    14881 aggctgccgg tttattccca ctggcgctga tgctttcagg ctgtatctcg tatgctctgg
    14941 tttcccatac cgcaaagggt agttcaggaa agtatcaatc gcagtcagac accatcactg
    15001 ggctatcgca ggcaaaagat agtaatggaa caaaaggcta tgtttttgta ggggaatcgc
    15061 tggattacct tatcactgat ggtgccgatg acatcgttaa gatgctcaat gatccagcac
    15121 ttaaccggca caatattcag gttgccgatg acgcaagatt tgttttaaat gcggggaaaa
    15181 agaaatttac cggcacaata tcgctttact actactggaa taacgaagaa gaaaaggcac
    15241 tggcaacgca ttatggtttt gcctgtggtg ttcaacactg taccaggtca ctggaaaacc
    15301 taaaaggcac aatccatgag aaaaataaaa acatggatta ctcaaaggtg atggcgttct
    15361 accatccatt taaagtgcga ttttatgaat actattcacc cagaggcatt ccggatggtg
    15421 tttccgcagc attactgcca gtgactgtta cgctggacat cattactgca ccgctgcaat
    15481 ttctggttgt atatgcagta aaccaataat cagtaagcgg gcaaacgcgt ttatgctgtt
    15541 tgcccgccca cagattaatt cagcacatac ttctcaatag caaacgccac gccatcttca
    15601 aggttagatt tggtgacaaa gttcgccact tctttcactg aaggaatagc gttatccatc
    15661 gccacaccga cgcctgcata ttcaatcatt gcgatatcgt tttcctgatc gccaatcgcc
    15721 atgatttctt ccggtttaat acctaacacg tcggccagtg atttcacccc cgtacctttg
    15781 ttaacgcgtt tatcgaggat ttcgaggaag tacggcgcac ttttcagcac ggtatatttc
    15841 tctttcactt cctgcggaat acgcgcgata gcctggtcga ggatggcggg ttcatcaatc
    15901 atcatcactt tcaggaactg ggtattgggg tccattttct ccgcttcgca gaacaccagc
    15961 ggaattgtgg caacgaagga ttcatgcacc gtgtagtagc tgatatcacg gttggcggtg
    16021 tacagcgtgg tgcggtccag ggcgtggaaa tgagaaccga cttcgcgaga gagtttttcc
    16081 aggaaacggt agtcgtcata gctgagagcg gtttgcgcca cggtgctacc atcagcggcc
    16141 ttctgtacca gcgcgccgtt ataagtaatg cagtagtcgc ccggcagttc catatgcagc
    16201 tctttcaggt aattgtgaac acctgcataa gggcgacccg tcgttagcac gacattcacg
    16261 ccacgggcgc gagctgcggc aatcgcattt ttaacggcgg gtgaaatggt gtgatcgggt
    16321 agcagaaggg tgccatccat atcgatagca atgagtttga tagccatgag ttccccaggt
    16381 agattagttc ctgacccatg ctaacgcgat tccgctcaaa aatcagtaca acacccgagg
    16441 gaaaaggggg atgcaacgcg ggttgcatgc tccccatttg cttagcggaa gagtttccct
    16501 ttcagcagtt ccatgcctgc ggaaagcaga tcgttattgg cttgtggtga cacttcacct
    16561 tgcggtgaga gcgcatcaat aatcttcggc aattgctctg ccagtaaact ggaagctgta
    16621 ctggtatcca cgccaagttt ttgcccgaga tcggacaccg catttgtgcc gagcgccgat
    16681 tccagttgct cgccactaac cgattgattg ccctgttgat tactcagcca ggttgagaga
    16741 atggccccta agccgccact ttgcagtttt tccagcagca cctgaatgcc gccctgctcc
    16801 tcaacccaac ttaaaatagc ctgatatttc cccgcatcgc ctttcagaaa ggcaccgaca
    16861 acttcatcaa aaagccccat gataatcacc tgtaaagcgt tacgtgttga cccaaaaagt
    16921 atagatttgc gggatgataa ttgcggattg cagaaataaa aagggcggag atgatctccg
    16981 cccttttctt atagtttctt gccggatgcg gcgtgaacgc cttatccggc ctacaaaatc
    17041 atgaaaattc aatacattgc aagattttcg taggcctgat aagcgtagcg catcaggcac
    17101 gctcgcatgg ttagcgccat taaatatcga tattcgccgc tttcagggcg ttctcttcaa
    17161 taaacgcacg gcgcggttca acggcgtcgc ccatcagcgt ggtgaacaac tggtcggcag
    17221 caatcgcatc tttaacggta acgcgcagca tacgacgact ttccgggtcc atagtggttt
    17281 cccacagctg ttccgggttc atctcgccca gacctttata acgctggatg gagaggccgc
    17341 gacgggactc tttcaccagc cagtccagcg cctgctcgaa gctggctacc ggctgacgac
    17401 gctcgccacg ttcgataaac gcatcttctt ccagcaagcc acgcagtttc tcacccagcg
    17461 tgcagatacg acgatattcg ccaccggtga taaactcgtg atccagcgga tagtcagtat
    17521 ccacaccgtg ggtacgcacg cgaacaatcg gctcgaacag gttttgttcg gcattggtgt
    17581 ggacatcaaa cttccactgg ctgccgtgct gttctttgtc gttcagttcg ctgaccagcg
    17641 cgttcaccca gcgggtaacg gtctgctcat cagagaggtc ggcttccgtc agcgtcggct
    17701 gatagataag ctctttcagc attgctttcg gataacgacg ctccatgcgg ttgatcattt
    17761 tctgcgtcgc gttgtactca gacaccagtt tctctaacgc ttcgccagcc aatgccggtg
    17821 cgctggcgtt ggtgtgcagc gttgcgccgt ccagcgcgat agagatctgg tactgatcca
    17881 tcgcttcgtc gtctttaatg tactgttcct gcttgccttt cttcactttg tacagcggcg
    17941 gctgagcgat gtagacgtga ccacgttcaa cgatttccgg catctgacga tagaagaagg
    18001 tcaacagcag cgtacgaatg tgcgagccgt cgacgtccgc atcggtcatg atgatgatgc
    18061 tgtgataacg cagtttgtcc gggttgtact cgtcacgacc gataccacag ccaagcgcgg
    18121 tgataagcgt cgccacttcc tgagaagaga gcatcttatc gaagcgcgct ttctcgacgt
    18181 tgaggatttt acccttcagc ggcagaatcg cctggttctt gcggttacgc ccctgcttcg
    18241 cagagccgcc cgcggagtcc ccttccacca ggtacagttc ggaaagcgcc ggatcgcgtt
    18301 cctggcagtc tgccagtttg cccggcaggc ccgctaagtc gagcgcacct ttacggcggg
    18361 tcatttcacg cgcgcgacgc gcagcttcac gggcacgggc agcatcgata attttgccaa
    18421 ctacgatttt cgcgtcggtt gggttttcca gcaggtattc tgccagcagt tcgttcatct
    18481 gctgttcaac cgccgatttc acctcagaag aaaccagttt gtctttggtc tgggaggaga
    18541 atttcgggtc cggcactttc acggaaacga ccgcaatcaa gccttcacgc gcatcgtcac
    18601 cggtggcgct gactttggct tttttgctgt agccttcttt gtccatgtag gcattcaggg
    18661 tacgggtcat cgccgcacgg aagcctgcca ggtgagtacc gccgtcacgc tgcggaatat
    18721 tgttggtaaa gcagtagatg ttttcctgga agccatcgtt ccactgcagc gccacttcaa
    18781 cgccaatacc gtctttttca gtggagaagt agaagatatt cgggtgaatc ggcgttttgt
    18841 tcttgtttag atattcaacg aacgccttga tgccgccttc atagtggaag tggtcttctt
    18901 tgccgtcgcg cttgtcgcgc agacgaatgg aaacgccgga gttgaggaac gacaactcac
    18961 gcagacgttt cgccagaatt tcatattcga actcggtcac attggtgaag gtttcgaggc
    19021 tgggccagaa acgcaccatg gtgccggttt tttcagtctc gccggtaacc gccagcgggg
    19081 cctgcggtac accgtgttcg tagatctgac ggtgaatttt accctcgcgc tggataacca
    19141 gctccagttt ttgcgacagg gcgtttacta ccgaaacacc aacgccgtgc agaccgccgg
    19201 acactttata ggagttatcg tcaaatttac cgcctgcgtg cagaacggtc atgatcactt
    19261 ccgccgccga tacgccctct tccgggtgaa taccggtcgg aatgccgcgc ccgtcatcct
    19321 gtacagagac agagttatcg gcgtgaatgg tgacgataat ttctttacag tgacccgcga
    19381 gcgcttcgtc gatagcgtta tctaccacct cgaataccat gtggtgcaga ccggtgccgt
    19441 catccgtgtc gccgatatac atacccgggc gcttacgcac cgcatccagc cctttcagga
    19501 ctttgatact ggaggagtca taagaattcg acatcaacgt ttctcgctca tttatacttg
    19561 ggttaatccg ttattttacc cttttccacg gtaaacatct tcgaattttc gtccgacatg
    19621 tctataacgt gttcagcact gatcgcgctg acaaagacct gtgattgcgt cgcttttaag
    19681 cggctggcaa gcagcccgcg acgctcatca tcaagctcag aggcaaaatc atctatcagg
    19741 tagagacacc gccgcccgct ttcacgggtg aggaactctc cttgcgccag acgtaaggcg
    19801 cacatcaaca gcttaagctg cccacgcgat aaggtatctt ccaccggcgc accgtcggcg
    19861 cgaatgcgta agtccgcttt gtgcgggccg tgcgcggtgt aggttagctg gcgatcgcgt
    19921 tcaaaattac gttccagcac ctcagcatat tctgtctctt tctcccagcc gcgctggaaa
    19981 gagaaagtca gagaaaactc agggagaaat tgcttacagg tatcagccat atcggccgcg
    20041 ataccggcgc tatactccgc gcgccaggtg ctgatttgct ccgccagcgg gatcagctct
    20101 ttatcccacg ggcgtagctg ttcgtaacgt gtcacctggc gcagcgccgc attgcgctgc
    20161 ttgagcaatc gcttgagatt gctccaggcg gtgaaaaatc cgggttcgtt gtgaaagcat
    20221 ccccagtcga ggaatgctct tctgtatttg gggccgccgt tgagtaaagt aaacccttct
    20281 ggcgttatca actgcattgg catcaggtgc gccagttccg cgaccttatg cccgtctgta
    20341 ccgtcgatgc ggactttgct gtcgccctgt ttgtctttgg ttaagccaat cgctgtctcg
    20401 cgctcttcgc cctgtaatcg cccgtggaga acaaacgcct cctgctcatg gcgaatgacg
    20461 cgaccaatct gcaaactgcg aaacgcccga ccatggccga gcgtatagat ggcttccagc
    20521 acgctggttt tgccactgcc gttggcacct accagaaagt taaagccggg agataaggcg
    20581 agatccgcgg tttcaatgtt gcggaaatcg cggatcaaca agcgggtgag ggacattaca
    20641 gtctcattgg catgacaaca taagccgcgc tctggctggc cgcatcttca atctgcacgc
    20701 tggaaaccga atcggtcagc atcatgcgga cgttttcgca tttcagcgcg ttcagaacat
    20761 ccagcacata actgacgttg aagccgattt ccatctccgc accgctatag gtaacgtcga
    20821 ggatctcttc cgcttcttcc tgttccgggt tgttggcggt gattttcagc tggttttcgc
    20881 tgacataaag acgtacgccg cggaatttct cgttagagag aatcgccgcg cgagcaaacg
    20941 cctgcttgag cagatcgcag ccagcttcca gatgtttgtc cgggttcttc ggcagaacgc
    21001 ggcgataatc cgggaagcga ccatccacca gtttggaggt gaagataaag tcgccaacgt
    21061 gggcgcgaat gttgttgctg ccaatctgta cgcgcagcgg attgtcgccg ccgtcgagca
    21121 tacgcatcag ttcaatcacg cctttacgcg gtacgatcac cgaatggctt ggcaaagatt
    21181 gaccaattgg cattgaacag accgccagac ggtggccgtc ggttgccacg gtgcgcagtt
    21241 cttcaccttc ggtttcaaac agcataccat ttaagtaata gcgaacgtcc tgatgcgcca
    21301 tagaaaactg ggtcgcttca atcagacgct tcatcgttgc ctgcggcagg gtaaattcga
    21361 cttcactctg ccagtcatcg aggttcggga aatccgccgc tggcagggta gacagcgaaa
    21421 aacggctacg cccggagcgt accagcatcc gttcaccttc cagctgcacg gcaatttccg
    21481 cgccttcagg cagaccacgg cagatatcaa agaatttgcg cgccggaacg gtcgtcgctc
    21541 ctggctcgtg tggctgaacc agcgcaacac gtgccaccat ttccatctcg agatcagtac
    21601 cggtcagcga caacgtaccg tcagcaacct gtaacagcag attaccgaga atcggtagcg
    21661 taggacgacc acctaacgga ccgctcacct gttgtagcgg ttttaataaa tgctcacgtt
    21721 ctacggtaaa tttcataggt ttacgatgac aatgttctga ttaaatttga aaaatcttct
    21781 ttgatatcgt ggctctcttc acgcaactgc tcgatcttac ggcaggcatg aagcaccgtc
    21841 gtgtggtcac gaccaccaaa cgcatcgcca atctccggca gactgtggtt agtcagctct
    21901 ttcgccagcg ccatcgccat ctggcgcgga cgcgccaccg agcgggatcg acgcttggaa
    21961 aggagatccg cgactttgat cttgtagtac tccgccaccg tcttctgaat attgtcgatg
    22021 gtgaccagtt tttcctgcaa tgccagcaag tcgcgcagcg cctcacgcac gaagtcgatg
    22081 gtgatcgccc gtccggtaaa gttggcattg gcaatgacgc ggttcagcgc cccttccagc
    22141 tcacgtacgt tagatcgtag acgcttggcg ataaagaacg ccacttcgcc cggcaaacga
    22201 atgtcgtttt cgtcggcctt tttcatcagg atcgccacac gggtttccag ctctggcggt
    22261 tcgatcgcca cagtcagtcc ccaaccgaag cgggatttca aacgatcctc aacgccgttg
    22321 atctctttcg gatagcgatc cgaggtgaga atgatctgtt gattaccttc cagcagggcg
    22381 ttgaaggtgt ggaaaaactc ttcctgagat cgttctttat tagcaaaaaa ctgaatatcg
    22441 tcgatcagca gtgcatctac ggaacggtag tagcgtttaa actcttcgat cgcgttgttt
    22501 tgcagggctt taaccatgtc ctgaacaaag cgctcggagt gcatataaac cactttggca
    22561 ttcggcttgc gcgccataat gccgttaccc accgcatgca gcaggtgagt tttacccaga
    22621 cccgtgccgc cataaaggaa caacgggtta taggcaccgc cagggttatc cgccacctgg
    22681 cgagccgccg cgcgcgccag ttggttagat ttaccttcaa cgaagttatc aaacgtgtgt
    22741 ttgacgttta cgttagaacg ataggtcggt tctgccgggg ccgggacgtt atcccaacct
    22801 gagcgcgtag aaggcgcagc acgttgcggc tgcgtttgcg ccacctgtgc aggggccgcg
    22861 acgttgctcg tcactgccgc ttgtggcgtt tgcgtcaccg gtttggtgcc gacttcaaaa
    22921 cgcagctgtg gggcatccgc tccgcagaaa ctggttagca gtccattgat attattaagg
    22981 tacttgtccc gtacccaatc gaggacaaaa cggtttggcg cgtacagggc cagcgtgtta
    23041 tcgctcagtt ccgcctgcaa tgggcgtatc cacatactga attctgtggc tggtaactca
    23101 tcctgcaatc gggcaagaca ctgctgccaa agcgaaagtg acacggcgga ctccactcga
    23161 acaaaagtcg ataatgacta aggctgaaac attcatgatt gttgacgtac gtcgaaaaga
    23221 ccctgcttga gggtgacgca cgaaccgctg tctgcggtta tatgcccgat caagatcctg
    23281 caaaacgatc gggaccgcgg atcatagcct aaactgcgca agagatcttc tgtttctcac
    23341 agattttccc gatttatcca caggactttc cagaactcgc taagtgtaaa cgatcctgcc
    23401 gcgaggcggg cacgatttac gccgcatatt ggaaaattta atgaccatag acaaaaattg
    23461 gcttaatcga tctaataaag atccaggacg atccttgcgc tttacccatc agcccgtata
    23521 atcctccacc cggcgcgcca tgctggtttc cactggtgtg aggtcgtaca ttttccctgc
    23581 gaaaaggtgc ggaaaagcgc ggtaaataag gaaagagaat tgactccgga gtgtacaatt
    23641 attacaatcc ggcctcttta atcacccatg gcttcggtgt ccatcgtttc atttttcggc
    23701 ggatatccaa taaagccatt gaatttattc aagtttaggt agaaatcgcc atgaaacgca
    23761 cttttcaacc gtctgtactg aagcgcaacc gttctcacgg cttccgtgct cgtatggcta
    23821 ctaaaaatgg tcgtcaggtt ctggcacgtc gtcgtgctaa aggccgcgct cgtctgaccg
    23881 tttctaagta ataaagctaa cccctgagtg gttaagctcg catttcccag ggagttacgc
    23941 ttgttaactc ccagtcaatt cacattcgtc ttccagcagc cacaacgggc tggcacgccg
    24001 caaattacca ttctcggccg cctgaattcg ctggggcatc cccgtatcgg tcttacagtc
    24061 gccaagaaaa acgttcgacg cgcccatgaa cgcaatcgga ttaaacgtct gacgcgtgaa
    24121 agcttccgtc tgcgccaaca tgaactcccg gctatggatt tcgtggtggt ggcgaaaaaa
    24181 ggggttgccg acctcgataa ccgtgctctc tcggaagcgt tggaaaaatt atggcgccgc
    24241 cactgtcgcc tggctcgcgg gtcctgatag ccctcattcg ggtctatcaa cgcctgatta
    24301 gtccgctact cgggccgcat tgtcgtttca ctccaacctg ttcaagctac ggaattgagg
    24361 cattgcgcag gtttggagtg ataaaaggca gttggttgac ggtgaaacgc gtattaaaat
    24421 gccacccttt acaccctggt ggtgacgatc ccgtcccgcc cggaccattt gataccagag
    24481 aacactaacg atggattcgc aacgcaatct tttagtcatc gctttgctgt tcgtgtcttt
    24541 catgatctgg caagcctggg agcaggataa aaacccgcaa cctcaggccc aacagaccac
    24601 gcagacaacg accaccgcag cgggtagcgc cgccgaccag ggcgtaccgg ccagtggcca
    24661 ggggaaactg atctcggtta agaccgacgt gcttgatctg accatcaaca cccgtggtgg
    24721 tgatgttgag caagctctgc tgcctgctta cccgaaagag ctgaactcta cccagccgtt
    24781 ccagctgttg gaaacttcac cgcagtttat ttatcaggca cagagcggtc tgaccggtcg
    24841 tgatggcccg gataacccgg ctaacggccc gcgtccgctg tataacgttg aaaaagacgc
    24901 ttatgtgctg gctgaaggtc aaaacgaact gcaggtgccg atgacgtata ccgacgcggc
    24961 aggcaacacg tttaccaaaa cgtttgtcct gaaacgtggt gattacgctg tcaacgtcaa
    25021 ctacaacgtg cagaacgctg gcgagaaacc gctggaaatc tcctcgtttg gtcagttgaa
    25081 gcaatccatc actctgccac cgcatctcga taccggaagc agcaacttcg cactgcacac
    25141 cttccgtggc gcggcgtact ccacgcctga cgagaagtat gagaaataca agttcgatac
    25201 cattgccgat aacgaaaacc tgaacatctc ttcgaaaggt ggttgggtgg cgatgctgca
    25261 acagtatttc gcgacggcgt ggatcccgca taacgacggt accaacaact tctataccgc
    25321 taatctgggt aacggcatcg ccgctatcgg ctataaatct cagccggtac tggttcagcc
    25381 tggtcagact ggcgcgatga acagcaccct gtgggttggc ccggaaatcc aggacaaaat
    25441 ggcagctgtt gctccgcacc tggatctgac cgttgattac ggttggttgt ggttcatctc
    25501 tcagccgctg ttcaaactgc tgaaatggat ccatagcttt gtgggtaact ggggcttctc
    25561 cattatcatc atcaccttta tcgttcgtgg catcatgtac ccgctgacca aagcgcagta
    25621 cacctccatg gcgaagatgc gtatgttgca gccgaagatt caggcaatgc gtgagcgtct
    25681 gggcgatgac aaacagcgta tcagccagga aatgatggcg ctgtacaaag ctgagaaggt
    25741 taacccgctg ggcggctgct tcccgctgct gatccagatg ccaatcttcc tggcgttgta
    25801 ctacatgctg atgggttccg ttgaactgcg tcaggcaccg tttgcactgt ggatccacga
    25861 cctgtcggca caggacccgt actacatcct gccgatcctg atgggcgtaa cgatgttctt
    25921 cattcagaag atgtcgccga ccacagtgac cgacccgatg cagcagaaga tcatgacctt
    25981 tatgccggtc atcttcaccg tgttcttcct gtggttcccg tcaggtctgg tgctgtacta
    26041 tatcgtcagc aacctggtaa ccattattca gcagcagctg atttaccgtg gtctggaaaa
    26101 acgtggcctg catagccgcg agaagaaaaa atcctgattc ggtgagtttt cgctaaaata
    26161 agggcggtca gttgaccgcc ttttttcttt tcgtagggcg gataagcacc gcgcatccgc
    26221 cacacaaagc aacaggaaca tcatgagcga taatgacact atcgtagccc aggccacgcc
    26281 tccgggacgt ggcggcgttg gcatcctgcg catctccggc ttcaaagccc gtgaagttgc
    26341 cgaaaccgtg ctgggtaaac tgcctaagcc gcgctacgcc gattatcttc cgtttaaaga
    26401 cgccgacggc agcgtgctcg atcaggggat tgcgctatgg ttccctggcc cgaactcgtt
    26461 caccggcgaa gatgtgctgg aactgcaagg tcatggcggt ccggtgatcc tcgacctgct
    26521 gttaaaacgc attctgacca ttcccggcct gcggattgct cgccctggtg agttttccga
    26581 acgcgcgttt cttaacgata aacttgactt agcccaggcc gaggcgattg ccgatcttat
    26641 cgacgccagt tcggaacagg cggcccgttc ggcacttaac tcgctgcaag gcgcattctc
    26701 cgcacgggtt aatcatctgg tagaagccct cacccacttg cgcatttacg tcgaagcggc
    26761 aattgatttc cccgatgaag agatcgattt cctctccgac ggaaaaattg aagcccagct
    26821 caatgacgtt attgccgatc ttgatgcagt gcgtgctgaa gcacgtcagg gtagtttgtt
    26881 gcgcgaaggg atgaaagtgg tgattgccgg acgtcctaac gccggtaaat cgagcctgtt
    26941 aaacgcgctg gcggggcgtg aagcggcaat cgtaaccgat atcgccggaa ctacgcgtga
    27001 cgtgctgcgt gagcatatcc acattgacgg aatgccgctg catatcatcg ataccgccgg
    27061 gctacgtgaa gccagtgacg aagtagaacg tattggtatc gagcgcgcgt ggcaggaaat
    27121 tgaacaggcc gaccgcgtgc tgtttatggt cgatggcacc acaacagacg ccgtggatcc
    27181 ggcagagatc tggccggaat ttattgcccg tctgccagcg aaactgccga tcaccgtggt
    27241 gcgcaataaa gccgatatca ccggcgaaac gctgggaatg agtgaagtga acggtcacgc
    27301 gttaattcgt ctctcggcaa ggactggtga aggcgtggac gtgctgcgta accatctcaa
    27361 acagagcatg ggctttgaca ccaacatgga aggcggcttc ctggcgcgtc gtcgccacct
    27421 acaggcgctg gaacaggcag cggaacatct acaacagggc aaagcgcaac tgttgggagc
    27481 ctgggcaggt gaactgctgg cggaagagtt gcgtctggca cagcagaact taagcgaaat
    27541 caccggggaa tttacttcag acgacctgct ggggcggatt ttctccagct tctgtattgg
    27601 taagtaaccg cgcttacgaa gccgcattct gactgtcaga tgcggcttcg cttcattgtt
    27661 accactcctg ttattcctca accctttttt taaacattaa aattcttacg taatttataa
    27721 tctttaaaaa aagcatttaa tattgctccc cgaacgattg tgattcgatt cacatttaaa
    27781 caatttcaga atagacaaaa actctgagtg taataatgta gcctcgtgtc ttgcgaggat
    27841 aagtgcatta tgaatatctt acatatatgt gtgacctcaa aatggttcaa tattgacaac
    27901 aaaattgtcg atcaccgccc ttgatttgcc cttctgtagc catcaccaga gccaaaccga
    27961 ttagattcaa tgtgatctat ttgtttgcta tatcttaatt ttgccttttg caaaggtcat
    28021 ctctcgttta tttacttgtt ttagtaaatg atggtgcttg catatatatc tggcgaatta
    28081 atcggtatag cagatgtaat attcacaggg atcactgtaa ttaaaataaa tgaaggatta
    28141 tgtaatggaa aactttaaac atctccctga accgttccgc attcgtgtta ttgagccagt
    28201 aaaacgtacc actcgcgctt atcgtgaaga ggcaattatt aaatccggta tgaacccgtt
    28261 cctgctggat agcgaagatg tgtttatcga tttactgacc gacagcggca ccggggcggt
    28321 gacgcagagc atgcaggctg cgatgatgcg cggcgacgaa gcctacagcg gcagtcgtag
    28381 ctactatgcg ttagccgagt cagtgaaaaa tatctttggt tatcaataca ccattccgac
    28441 tcaccagggc cgtggcgcag agcaaatcta tattccggta ctgattaaaa aacgcgagca
    28501 ggaaaaaggc ctggatcgca gcaaaatggt ggcgttctct aactatttct ttgataccac
    28561 gcagggccat agccagatca acggctgtac cgtgcgtaac gtctatatca aagaagcctt
    28621 cgatacgggc gtgcgttacg actttaaagg caactttgac cttgagggat tagaacgcgg
    28681 tattgaagaa gttggtccga ataacgtgcc gtatatcgtt gcaaccatca ccagtaactc
    28741 tgcaggtggt cagccggttt cactggcaaa cttaaaagcg atgtacagca tcgcgaagaa
    28801 atacgatatt ccggtggtaa tggactccgc gcgctttgct gaaaacgcct atttcatcaa
    28861 gcagcgtgaa gcagaataca aagactggac catcgagcag atcacccgcg aaacctacaa
    28921 atatgccgat atgctggcga tgtccgccaa gaaagatgcg atggtgccga tgggcggcct
    28981 gctgtgcatg aaagacgaca gcttctttga tgtgtacacc gagtgcagaa ccctttgcgt
    29041 ggtgcaggaa ggcttcccga catatggcgg cctggaaggc ggcgcgatgg agcgtctggc
    29101 ggtaggtctg tatgacggca tgaatctcga ctggctggct tatcgtatcg cgcaggtaca
    29161 gtatctggtc gatggtctgg aagagattgg cgttgtctgc cagcaggcgg gcggtcacgc
    29221 ggcattcgtt gatgccggta aactgttgcc gcatatcccg gcagaccagt tcccggcaca
    29281 ggcgctggcc tgcgagctgt ataaagtcgc cggtatccgt gcggtagaaa ttggctcttt
    29341 cctgttaggc cgcgatccga aaaccggtaa acaactgcca tgcccggctg aactgctgcg
    29401 tttaaccatt ccgcgcgcaa catatactca aacacatatg gacttcatta ttgaagcctt
    29461 taaacatgtg aaagagaacg cggcgaatat taaaggatta acctttacgt acgaaccgaa
    29521 agtattgcgt cacttcaccg caaaacttaa agaagtttaa ttaatactac agagtggcta
    29581 taaggatgtt agccactctc ttaccctaca tcctcaataa caaaaatagc cttcctctaa
    29641 aggtggcatc atgactgatc aagctgaaaa aaagcactct gcattttggg gtgttatggt
    29701 tatagcaggt acagtaattg gtggaggtat gtttgcttta cctgttgatc ttgccggtgc
    29761 ctggtttttc tggggtgcct ttatccttat cattgcctgg ttttcaatgc ttcattccgg
    29821 gttattgtta ttagaagcaa atttaaatta tcccgtcggc tccagtttta acaccatcac
    29881 caaagattta atcggtaaca cctggaacat tatcagcggt attaccgttg ccttcgttct
    29941 ctatatcctc acttatgcct atatctctgc taatggtgcg atcattagtg aaacgatatc
    30001 aatgaatttg ggttatcacg ctaatccacg tattgtcggg atctgcacag ccattttcgt
    30061 tgccagcgta ttgtggttaa gttcgttagc cgccagtcgt attacctcat tgttcctcgg
    30121 gctgaagatt atctcctttg tgatcgtgtt tggttctttt ttcttccagg tcgattactc
    30181 cattctgcgc gacgccacca gctccactgc gggaacgtct tacttcccgt atatctttat
    30241 ggctttgccg gtgtgtctgg cgtcatttgg tttccacggc aatattccca gcctgattat
    30301 ttgctatgga aaacgcaaag ataagttaat caaaagcgtg gtatttggtt cgctgctggc
    30361 gctggtgatt tatctcttct ggctctattg caccatgggg aatattccgc gagaaagctt
    30421 taaggcgatt atctcctcag gcggcaacgt tgattcgctg gtgaaatcgt tcctcggcac
    30481 caaacagcac ggcattatcg agttttgcct gctggtgttc tctaacttag ctgttgccag
    30541 ttcgttcttt ggtgtcacgc tggggttgtt cgattatctg gcggacctgt ttaagattga
    30601 taactcccac ggcgggcgtt tcaaaaccgt gctgttaacc ttcctgccac ctgcgttgtt
    30661 gtatctgatc ttcccgaacg gctttattta cgggatcggc ggtgccgggc tgtgcgccac
    30721 catctgggcg gtcattattc ccgcagtgct tgcaatcaaa gctcgcaaga agtttcccaa
    30781 tcagatgttc acggtctggg gcggcaatct tattccggcg attgtcattc tctttggtat
    30841 aaccgtgatt ttgtgctggt tcggcaacgt ctttaacgtg ttacctaaat ttggctaaat
    30901 ccttcaagaa gccagccatt cgctggcttc ttgcctctca ggaaatcact tatgtccaaa
    30961 tggcaactcg cctgatcctc cttcaccacg tatgctttgc gtcaccttac tatcaggacg
    31021 ctttagccta tgtcccgctt tttgatttgt agttttgccc tggttttact ttatcccgcc
    31081 gggattgata tgtacctcgt tggtttaccg cgcatcgccg ccgatctcaa tgccagcgaa
    31141 gcgcagttgc atattgcgtt ctccgtatat ctggcgggga tggcagctgc gatgttattt
    31201 gccggtaaag tggccgatcg ttcagggaga aagccggtcg ccatacccgg cgcggcgcta
    31261 tttattattg cctcggtgtt ctgttcactg gctgaaacca gcacgttatt tcttgcaggc
    31321 cgatttctac aggggttggg cgcaggctgt tgttacgtag tggcgttcgc tattttgcgc
    31381 gacacgctgg atgatcgacg tcgggctaaa gtgctgtcat tactcaacgg tattacctgc
    31441 atcattccgg tgttagcgcc agtgctcgga catctgatta tgcttaaatt cccgtggcag
    31501 agtctgttct gggcgatggc aatgatgggc atcgcggtac tgatgttgtc tttgtttatt
    31561 ttaaaagaaa cgcgcccagc ggcccccgca gcttcggata aaccacgaga aaatagcgag
    31621 tcgctgctta accgtttttt cctcagccgt gttgttatca ccaccctcag cgtttcggtg
    31681 atcctcactt tcgtcaacac gtcaccggta ttgctgatgg aaatcatggg gtttgagcgc
    31741 ggtgaatacg ccaccattat ggcgctgacc gctggcgtca gcatgaccgt ttcattctcc
    31801 acgccatttg cgctgggaat ttttaagcca cgtacgttga tgatcacctc gcaggtgtta
    31861 ttcctggcgg cggggatcac tcttgccgtt tcaccttccc atgcggtttc tctgtttggt
    31921 atcacgctga tttgcgccgg tttctcggta ggttttggtg tggcgatgag tcaggcgtta
    31981 gggccgtttt cattacgcgc gggcgtagcc agctcgacct taggtattgc gcaggtttgc
    32041 ggttcgtcac tgtggatttg gctggcagcg gtggttggta tcggcgcatg gaatatgctg
    32101 atcgggattc tgattgcctg tagcatagtg agcctgttgc tgattatgtt cgtcgcgcct
    32161 ggacgccccg ttgccgctca tgaagaaatc catcaccacg cttgatctca atctgctgct
    32221 ttgtctgcaa ctgctgatgc aggagcgcag cgtaaccaaa gcggcgaagc ggataaacgt
    32281 gacaccttcg gcggtgagta agtcgctggc aaagttaaga gcgtggtttg acgacccgct
    32341 ctttgtgaac tcaccgctgg gtctgtcgcc cacaccgctg atggtcagca tggagcaaaa
    32401 tctggcggag tggatgcaaa tgagcaacct gctgctggat aaaccgcacc accagacacc
    32461 gcgcggcctg aagtttgagc tggcggcgga atcaccgctg atgatgatca tgcttaatgc
    32521 gctgtcgaaa cagatctacc aacgttaccc gcaggcgacc atcaaattac gtaactggga
    32581 ttacgattcc ttagatgcca ttactcgtgg tgaagtggat atcggttttt ccggtcgcga
    32641 aagccatcct cgctcgcggg agctgttaag ctcgctaccg ttagccattg attatgaagt
    32701 gctgtttagt gatgtgccct gcgtctggtt acgcaaagat catccggcac tgcatcaaac
    32761 gtggaatctg gacaccttct tacgttatcc gcatatcagc atttgctggg aacagagcga
    32821 tacctgggcg ctggacaatg tgttacagga gctgggacgc gaacgcacga ttgctatgag
    32881 cctgccggaa tttgagcagt cactgtttat ggcagcgcaa cccgacaatc tgctactggc
    32941 gaccgcgccg cgctactgtc agtactacaa tcaactccat caactgccgt tggttgctct
    33001 tcctctcccg tttgacgaaa gccagcaaaa aaagctggaa gttcctttta ccctgctgtg
    33061 gcataaacgg aacagccata atccgaagat cgtctggtta cgggaaacca ttaaaaacct
    33121 ttacgcgtcg atggcataac cgaatcgtat gaaacgcgac ccaatttcac aataaaatgt
    33181 aaaaaagttg taataagctt gtctgaatcg aacttttagc cgctttagtc tgtccatcat
    33241 tccagtaaat gattactctt atattcataa tggaccatta agcatggagc gaaaaatggc
    33301 gactcacttt gcccgaggga ttttaacgga aggacatctg atttctgttc gtctcccctc
    33361 ccagtgtcat caagaagccc gaaacattcc ccctcatcgt caaagccgtt ttctggcgtc
    33421 cagaggttta ctcgcagaac tgatgttcat gctgtatggc attggcgaat tgccggaaat
    33481 cgtcaccctg ccgaaaggta aaccggtttt cagtgataaa aatttgcctt cgttttctat
    33541 ttcctatgcc gggaatatgg ttggcgtggc gttaacaacc gaaggtgaat gtggcctcga
    33601 tatggaacta cagcgtgcga cgcgcgggtt tcatagccca cacgcgcccg ataaccacac
    33661 cttttccagc aatgaatcgc tatggatcag taaacaaaac gatcctaacg aagcgcgggc
    33721 gcagctcatc acgctgcgcc gaagcgtgct aaaactaacc ggtgatgttt tgaatgacga
    33781 tccgcgcgat ctgcagctgc agcccattgc cggacgcctg aaatgtgctc atgtaaatca
    33841 tgtagaagcg ttatgcgacg cggaggacgt gctagtgtgg tccgtggcgg tcacgcccgc
    33901 gattgaaaag ctcagtgtct gggagttaga tggcaaacac agctggaaaa gcctgccgga
    33961 tattcacagc cgcgccaaca atcctaccag ccggatgatg cgttttgccc agctctctac
    34021 cgtgaagtct ttttcgccaa attgatagac aaccacagga gtcattatgt ctgaaaaatt
    34081 gcaggtggtt acgttactgg ggagcctgcg caaaggctca tttaatggca tggttgcacg
    34141 taccctgccg aaaattgctc cggcgagcat ggaagtcaat gcgttacctt ccattgccga
    34201 cattcccctg tatgacgctg acgtacagca ggaagaaggt tttccagcaa cggttgaagc
    34261 tctggcggaa cagatccgtc aggctgacgg tgtggtgatc gtcacgccgg aatataacta
    34321 ctcggtaccg ggtgggctga aaaatgccat cgactggctt tcccgcctgc cggatcaacc
    34381 gctggcgggt aaaccggtgt tgattcagac cagctcaatg ggcgtgattg gcggcgcgcg
    34441 ctgtcagtat cacctgcgcc agattctggt tttcctcgat gcaatggtga tgaacaagcc
    34501 ggaatttatg ggcggcgtga ttcagaacaa agttgatccg caaaccggag aagtgattga
    34561 tcagggtacg ctggaccacc tgaccgggca attgaccgca tttggtgagt ttattcagcg
    34621 agttaagatc taaataaaaa acccgccagt aatcatgcat ggcgggtttt taacgcgcta
    34681 tcgattttag tgagcgtcga taaagacaat cttcaggata aacagcagcg caacgatgat
    34741 tacgcacggg cttagatcac gcagacgtcc ggtaccgatt ttcatcacgc agtaggagat
    34801 aaagcccagc gcgatacctt cggtaatcga gaagctgaac ggcatcatca cggcggtaat
    34861 aaacgccgga acagattcag taagatcctg ccagttcacg cgtgccagac tggaagtcat
    34921 cagcacgcca acgtaaatca gcgcaccagc tgcagcgtag cctggcacca tccccgccag
    34981 cggcgacaga aagataacca gcaggaacag cagaccaaca accactgccg tcagaccggt
    35041 acgaccgcca accgatacgc cggaagagga ctcaatataa gccgtaacgg aagaagtacc
    35101 gataaacgaa ccggtcacgg aagagatact gtcgacatac agcgcctgct tcatgcgcgg
    35161 gaatttaccc ttctcatccg ccaggcctgc tttatcggtc acgccaatca gcgtaccgga
    35221 ggagtcaaac aggttgacca gcatgaaaga gaaaatcacc cctgccagcc cgaggttaaa
    35281 cgactcggct aaatctacat ggcccacgac agtcattacg ctcggcggcg cagaaacgat
    35341 gccattgtag tggacatcac ccagcatcca gcccagcagc gttgtcacca cgatggaaac
    35401 cagcaccgcc gcgtgaatgt tgcgcgaggc cagaatagcg atgatgaaga agccgaggat
    35461 ccccagcagc acgctgtgag aagtcaggtt accgatgctc accagcgttt ccgggttagc
    35521 gacaatcaca cctgcattct tcagtcccat cataccaatg aacagaccga taccgctggt
    35581 gatgcccaca cgcagactta ccggaatgtt ggcaatcatc cagtagcgaa cgcggaaaat
    35641 cgtcagtaac agcagaccaa tcgcccccca gaagattgcg cccatcccga cttgccacgg
    35701 caagcccatc gcctgcacaa ccacaaaagc gaagaacgca ttcaggccca tagcgggtgc
    35761 cagtgcaact ggcaggttag caaacagtcc catcataata ctgccgaatg cagcaatcag
    35821 acaggtagta acgaagacgg cgctggtatc catgccagca acgccaagaa tttgcgggtt
    35881 aacaaaaacg atgtaaacca tcgtcaggaa ggtggtaaaa ccggcgatca cttcggtccg
    35941 tgccgtcgtg ccatgttcgc gcagtttaaa cacgcgttcc agcatcccct ggccagaagc
    36001 ctgggttgtg tgttgttgac tcattatcta tttccgaaca aggagggaaa atccgtcgct
    36061 atcgtatacc aaaatgagac aatatggacg gctgaagata actttttttc attgtatttg
    36121 cttatacggc aacgattgcg tcatgcgaat tggcatgacg aaaacgttaa actaacgata
    36181 aaggaaagac atgtcccaga tagaagcggt atttttcgac tgcgacggta cgctggtcga
    36241 tagcgaggtc atttgctctc gcgcatatgt aacgatgttt caggaatttg gtattacgct
    36301 cgatcctgaa gaggtattca aacgtttcaa gggtgtaaaa ctgtacgaaa ttatcgatat
    36361 tgtttccctt gaacatggtg ttacgttagc gaaaacagaa gctgaacacg tttaccgtgc
    36421 agaagtcgct cggctgttcg attcagaact ggaagccatc gaaggggctg gagcgctcct
    36481 gtcagcgatc actgcgccaa tgtgtgtggt atctaacggc ccaaataaca aaatgcagca
    36541 ttctatgggc aagctgaata tgttgcacta cttcccggat aaactgttca gcggctacga
    36601 tattcagcgc tggaagccag acccggcgtt aatgttccat gcggcaaaag cgatgaatgt
    36661 aaatgtagaa aactgcattc tggttgatga ctcagttgcc ggtgcgcaat ctggtatcga
    36721 cgcaggtatg gaagtgttct acttctgcgc cgacccgcac aataagccga tcgttcaccc
    36781 gaaagtcacc acctttaccc atctttcgca gttaccggaa ctgtggaaag cgcgtggttg
    36841 ggatattacg gcatagttct tcacactccc ttcacttacc ccgcttaaat tggcgctcaa
    36901 aggtaagtta agggtgtttg atatgtctgt ttcacgtcgg gtaatacatc acggacttta
    36961 ttttgcggtt ttaggaccgt taattggtgt tctgtttctt gtcctctaca tattcttcgc
    37021 aaaagaaccg ctggttcttt tggtaataat acaggtactt ccattgtttc tcttattgtc
    37081 gattactacg ggagctattc ctgcattgtt aaccggcgtg atggtcgcct gtctgccgga
    37141 aaagatcggg tcacagaaaa attatcgttg tctggctggt ggcataggtg gcgtcgttat
    37201 caccgagatc tattgtgcag ttattgtaca tattaagggc atggcttcct cggagttgtt
    37261 tgaaaacatt ctttctggtg acagtctcgt tgtccgcatc attcctgcat tgctggcagg
    37321 tgtggtgatg agcagaatca ttacccgtct gcccggattg gatatttcat gtcctgaaac
    37381 agactcttta agttaagcgg gatactttat ctttgggcta ctcaaaagca gacaggatgt
    37441 tactatgact caaaatatca ggccgttacc ccaattcaaa tatcatccca agccactgga
    37501 aacaggcgca tttgaacagg ataaaaccgt agagtgcgat tgctgtgaac aacagacgtc
    37561 agtttattac tcgggtccct tttattgcgt tgatgaagtt gaacatctct gtccgtgatg
    37621 tattgcggac ggttctgctg ctgaaaagtt tgcaggtagt tttcaggatg atgccagcat
    37681 agaaggtgtt gaatttgagt atgatgaaga ggacgaattt gccggtatta agaacacata
    37741 tcctgatgaa atgctgaaag agttggttga acgcacgcca ggttatcatg gatggcaaca
    37801 ggaattctgg cttgcgcatt gtggcgattt ctgtgctttt atcggctatg tgggctggaa
    37861 tgatataaaa gatcgcctcg atgaatttgc caaccttgaa gaagattgtg agaatttcgg
    37921 tattagaaat tctgatctag ctaaatgcct gcaaaagggt ggtgattgtc agggttatct
    37981 cttccgctgt ctccactgcg gcaagctgag actgtggggt gatttttcgt agttatttaa
    38041 ataatgagaa caggccggag cgtaattcat acatccggcc ttatttcttc agcttaaccg
    38101 agcgctaatt ctgcggcagc ggctttatca gcgattacca tcagcgaagg atgcagctgc
    38161 aacacggaag ctggaacatc ttcggtaacc ggaccttgca gcacattttt cagtgcctgc
    38221 gctttacttg cgccactgac aattatcagc aagtttttcg ccgccatgat gcttttcggc
    38281 cccatcgtca cgtagctgtc aggcactaac gaaaagtcgc cgcccaactc accatgcgcc
    38341 acaatatcaa ccatctctcc ctggatcggg aactccacgg tttgctcatg gaaatgggtc
    38401 gtattcggca aattgccaca aaaatgacca tctgcaccta atcccagcac caccaaatcc
    38461 aggccgcctt cacgcgccag tttctgatca tgctcgcggt agttatcaat agtgagcttc
    38521 tggatattct cttctttgat ccccgcaggg gtgaaaaaca gattacgcag attggtaatc
    38581 gttacgcctt ctccctcttt gccgcgaaag ggaatttcat cgaaattata gaaatagcag
    38641 ttatcgtacc agggcttacc tttaaccagg gtggtgaggt attcatacat gcctttgggc
    38701 gtgctaccgg cggtaattgc caggttaaca cgacgcgtct tcgacatata accaagcaga
    38761 tggtgtgccg cgacacggct catttcctgg taatcttcgg taatgattaa tttcatctta
    38821 atgccttatt ttatttaaat aatttctgta cgaaggctgc ataggcaggc cgccagacat
    38881 ccatttcatg gttcaggccg ggatattcct ggtaatcaaa cttaattttt ttctgctcaa
    38941 gctcagtttt cagcccggcg atatccttgc cggttacgac atctttatca ccaacgacca
    39001 cagtaaaatt acgtagttgc tggttaatag ctgccggatc gttcagccgg gccgcgacac
    39061 cttcatccgg tacggttgtc gtggtaacac cactgaatgt ggccagccag ccaaagcttt
    39121 ccagatgatt cattccggaa accagcgcct ggtacccgcc ttgtgaaagc cctgccagcg
    39181 cgcgaccatc ggcatcttta cggacattaa aacgcttgct aatcagcggg ataatatcgt
    39241 tcatcagttc gcgatctgcc gctttagcat tcagcggata aaagacttta cgtctttcct
    39301 gaggcacgaa atcttcggga ataatgccct tcgcatcggt ttcggtatcc gggatcacca
    39361 ccagcatcgg tttaattttc ccttcagcca gcaggttatc catgatttgc gggatacgcc
    39421 cctgatcgat agcggaacgt ccggtatcac caaaaccgtg atagaaatag agcactggca
    39481 aaggctcgcc catgccggtg tatcctggcg gggtccagac atacatctga cgttcagatt
    39541 gcaatgcgtt ggagtggtaa gttatggcga tcaaatcacc atgcgcaaca gaacgcgtat
    39601 ccagataact gcctggcacc agaatcatac tggagttaac ctggcgctga ggcttagtca
    39661 ttgcggtgcc tgtatcaatg ctgcgtacac catcaacatt gaaaaaatac tcgtacaggt
    39721 tgcctttcag gataggtgtg cgccacgacc agactcctgc ttcgtctttg gtcatcgggt
    39781 gaatattgtc cggaaccgga acacccacca ctacagagac attttttgcc ccaggggcaa
    39841 agtagcgaaa ggtcacgctg ttatcggcat tgacctgagt cacatactgt ttcaccggga
    39901 tagtgggtgc cgggctggct ggcatatccg ctgctatggc ccactgagca gaaataccgc
    39961 tggcaatagc cagcgttaaa gcagcaattt ttatattcat cgtaatattc ctttcattaa
    40021 gttccattac caccagattt cagcctgggc accgacagca aactggtcgt ctttattgtc
    40081 ttcgaaggtg aagccatcca gttcgttttc cagggctttg atatacgtgg cgtagaaacg
    40141 aatttccgga cgcgaggtca acatactggt attgacttta aaggtatgga agagcgtggt
    40201 tttataacca gactcattaa atttattact attcgcatct ttgttttgct gggtgaaata
    40261 gcccagttca acacctgtct ggttatattg gtcccaaata taggccgggc gaacaaccgc
    40321 acgaatagat tcgaaatcag agtgtgcgcc tgtttcgtag ctataaatat cgttaccgaa
    40381 ggagtaaaca atcgcgttag ccacaataaa atgatcaccg atataggctt cgccctgcga
    40441 ggtcagacga actgctgttc cgccggtgtg atcaccataa taacgaccat taaaggtggt
    40501 aaatggactt gcgccagcat aacggccaaa gttactggcg atagagttat tcgcaaccag
    40561 gaaggagaat tcgttgaagc cacctttatc aaatttctgc gttaaagatg tgccgaacat
    40621 ccaggtatct ttccagtcat aatacccgtt attatcctga ttatcttttt ccgatgcgct
    40681 ttcgtttgcc gtgacataac gaccactcac cattaaggtc gctttatccc ataacgggat
    40741 atctttatag cgtaaatcaa tagtattggt attaatctgc tgtttgtttt gcaggctgcg
    40801 atcgtaatca tcgacatctt cgcgaaccag cgcgatatca attttacccg gaccgacttt
    40861 ccagttttcc agacctacac ccgctgcggc atcagtacgc tgcgttttcc agtccagcat
    40921 ctggatttca attttcggcg caccgtgttt acccacccag aaatcagcct ctggcgcaaa
    40981 gggcaggaaa cctttggtgg taacgtacat atcggagaac tgcatatagt tctcgccacc
    41041 ggcgttatcg ccaaaccagc cggtagagta ctgctgacca acgttaccat ccatcatcac
    41101 aacggcatca acccgtttgc cgttttcgtt gtagacacgt tgttttaact gcaaatcaaa
    41161 ccagccggag tattcgttac caaagcggcc cagagaacca atcgcccatg atttaggtga
    41221 accatgagag gcggtccccc aaccagaacg gtaatagccg ttgtaactaa agccaatttc
    41281 atctttcaca aatttactga aatctttcag agtcatggaa gaataaatcg agcctgtctc
    41341 actggcattt ttctcttcat ttttgaccag tacagcatca ggttttgcgg cactactggt
    41401 cgggaacgga ttggcggcat acccttgatc attcgtactt acgctacgat tcaccgtcgc
    41461 tggcgtatac tttttcttct cttcatcttt atactttttg agttcgcttt gcgtttctct
    41521 taacgccttt tctaataact caaggcgttg ttccaccgtt aatgattcag ccaatgattg
    41581 tgcagaaaag gctaacggtg ccattaataa gatggcagag gtaataagat ttcgtctaaa
    41641 cataatatcc ctttatggtg caaagaaaga attaacgcat cgcatccaga ctgttctgaa
    41701 tgcgacgata attaaggtgc tttaatggtt atttttttta atgacagccc ccgcgtcttg
    41761 atcacctctg cataccatcc gaagcttttc ttgcgtgttc ttgtgaggct tccttcgcca
    41821 ttatcatcac gatccacata aataaagccg tagcgcttag acatttgtga atgagatgca
    41881 ctgactaaat caattggccc ccaactggtg taccccataa tatccacacc atcggcaatc
    41941 gcttcattta cctgtaccag gtgatcgttt aaataggcaa ttcgataatc gtcctgtatc
    42001 gaaccatccg cttcaacgct gtcttttgcg cctaatccgt tctcgacaat aaataacggt
    42061 ttttgataac gatcccaaag cgtatttaac agaacccgta atccaaccgg atcaatttgc
    42121 cacccccact ctgaactttt cagatgcgga ttggggatca tattcagtat gttgccctgc
    42181 gcatttttat taatgctttc gtcgtgggaa acacaaccag tcatgtaata actaaaagag
    42241 atgaaatcga cggtatgttt taaatcttct gcgtcacttt cagtcatctc aatggtgata
    42301 ttgtggtcgc ggaagaaacg ctgcatatag ccgggatact ggccacgcgc ctgaacatca
    42361 ccaaagaaca tccagcgccg gttctcttcc atggcctgca acatatcctg tggctggcag
    42421 gtgagggggt aaaccagccc accgagaagc atattgccga ttttcgcttc ggggagcagg
    42481 ctatgacagg ctttaactgc ccgcgcactg gcaaccagtt gatggtggat agcctgataa
    42541 acttccgcct cgccactctc ttctgccagc cccacgcccg tgaatggcgc gtgtaacgac
    42601 atgttgattt cattaaacgt cagccataac gccactttat gttggtagcg agtaaagacc
    42661 gtgcgggcgt aatgctcgaa gtgatcgatg accgctcgat tagcccaacc gccgtagttt
    42721 ttcaccagcc catatggcat ttcgtaatgg gataacgtta ccagcggctt gatccccgcc
    42781 tgcgccattt catcaaacag ccgatcgtaa aacgctaacc ccgcttcatt cggttcgact
    42841 tcgtcgccct gagggaaaat tcgcgcccag gcaatggaaa tacgcagaca ggtgaagccc
    42901 atctcggcaa ataacgcgat atcttccggg taacggtgat aaaaatcgat ggcgacatct
    42961 ttgatattct ctttccccag gatgcgcggt tccatttttc ccattacgcc atgaggctgt
    43021 aaatctgagg tcgagatccc tttgccatct tcctgccagg caccttccac ctgattggca
    43081 gctgttgcgc caccccaaag aaatgtttct ggaaatgctt tcataattaa ctccttttat
    43141 cgttagcgaa tgatggataa cagcggttca cctgcgctta tctgcgccgt gccgtggggt
    43201 aatacgtccg taaaatcatc gctattactg attaataccg gcgtcgtcag atcaaatccg
    43261 gcctcgcgaa tagcagggat atcaaaagaa atcagccgat cgcctgtatt gaccttgtca
    43321 cccacgttga cgtgagcgga aaagaatttg ccgtccagtt ttacggtgtc gataccgaca
    43381 tgaatcagga tctccacacc atcatctgac tcaatgccaa tggcgtgtaa tgtggcgaac
    43441 aacgaagcaa ttcgacccgc aaccggagaa cgcacttcac caaccgaggg cagaatggca
    43501 atacctttac ccaacaggcc actggcaaac gtggtatcag cgacgtgaat gagcggcaca
    43561 atctctcccg tcatcggtga acagataccg ccctgctcag gtggtgtaat aacctctggt
    43621 gttttctctt gcggggcacc ctgcgctggc tgacgtttag cggtgatgaa atgaagcatc
    43681 accgtaccga caaatgcgca accgatggca atgacaccgc caataacgct ggcccagacg
    43741 gtgaaatcaa ttcccgttga cgggatggtt tgcatgaagg tgaaaatact tggcaaacca
    43801 aaggagtaga ctttcgtttg cgcgtagcca atgatggtgg cccccaaagc cccactgata
    43861 caggcgataa caaaggggta cttacgcggc aggttgacgc catataccgc tggttcggtg
    43921 ataccaaaca gactcgtcaa cgccgctgat cccgccacca cttttttctg cgcatcgcgt
    43981 tcgcagagga agacgccgag cgccgccccg acctgcgcca taatggcggg cattaacagc
    44041 gggatcatgg tgtcgtagcc cagcacggtg aagttattga tacacagcgg caccaggccc
    44101 cagtgcagtc cgaacatgac gaagatttgc cagaagccgc ccattaccgc gcccgcaaat
    44161 gcaggaaccg cctgataaag ccagagataa ccggcggcaa tcagttcgct tatccaggtt
    44221 gatagcggcc ccaccagcag aaaggtgacg ggtgtgataa ccatcagaca tagcaatggt
    44281 gtgaagaaat ttttgattgc cgacggtaac cacgcattaa gtcggcgttc cagaatgctg
    44341 cacaaccagg cagaaaaaat aatgggaata accgatgacg agtaattcaa caatgtgacc
    44401 ggaataccca ggaaatccag ccccagcgca tccgcttttt gcccgttctc gaaagcagtc
    44461 agaattaatg gatgcactaa cgctccacca atcaccatgg cagtaaatgg attaccgccg
    44521 aagcgtttcc ccgcggtgta tcccaggatt atcgggaaga accaaaacaa ggcatcactg
    44581 gcgctgaata aaattaaata agtaccactt tgttcggtcg tccactgaaa agtgagcgcc
    44641 agagccagca tacctttcaa gatcccggtt gccgccatca aaccgatcag aggcgtaaaa
    44701 atacctgaaa taacataaac aaagcggttt agcagattac ctttatcatc attttccggt
    44761 gcctgttgcg ctttttcgtc aaggcctgcc acactgttaa ccgccaggaa gacatcggcc
    44821 acatggttac ctatgaccac ctgaaactgg ccaccgcttt ccaccaccat aataataccg
    44881 ggggtctttt tcagtacctc tgcttgcgct ttgctttcat cctttaattt aaaacgtaat
    44941 cgcgttgcgc aatgcatcag actcacaatg ttatctgcgc ccccgactcc tgcgactatt
    45001 tttctggcta actccgtcat aacttgccct ctaccgcttt gcggcaaaac tccaaaaaaa
    45061 aacctgaaaa aaacggcctg acgtgaatca agcaattttt ttcaggtttt gcccgcttag
    45121 tgcggtaaca atcctttact cagtaataat atttcagtgt tctttgcgca cgcgctctat
    45181 atttatggct aaaaacataa tctctgcggg tgaaatttta cgttgatact gcaaaccaat
    45241 aaaaatggcg atccgttccg cacattgcca tgcttgcggg taattttgtt ttactgcttg
    45301 ttgtaatgat tcatcactat cgttaattga agcatgttca agaatacgcc aggataaaaa
    45361 cttcagatgt gtaaccagtc gctgataact caagctttct tcctggtaat taaggctgaa
    45421 ctgaaatttt attaattgca gcatttcgcg cattaactgc gtgacacctg caacatcctc
    45481 catatttccg ctcatttggg cactgaccag atgcatggca ataaagccca cttcatcttt
    45541 cggtaactgc acgcccaacc gtttatcaat aatggttaac gcttcttccc ctagctggaa
    45601 ctctttcggg taaagccgct ggatatccca cagcaacggg ttgggcagca acacgttttg
    45661 ctgaaagcgt ttaatcgcaa actggcaatg gtcagttagc gagatataaa tactgtcctg
    45721 taattttccc aagcgctcct gcgctaaaga gataatacga tcacaggttg ccatcacctc
    45781 aagaggaata tgacttaaga gttcgcttaa tcgcccgttc agttcatgac tgctcaaggc
    45841 atactctttt tctattccac ttgagttaat tctttcgcca gcgcgttttt gaaagccaat
    45901 tccgcgcccc atgacgactt tttcccgctg ttgatcatca ataaccacca caacattatt
    45961 gttgagaatt ttggtgattt gcatgttcat agcaaggacc ttttttataa acaaaaaaac
    46021 ccgacttcac cagtattctc tggttatgtc aggttttgcc tgcgaatgca gtaacaatcc
    46081 agtcatttat taatggtttt tataacgaac atccaggttc ggaaattaat ttaattgcgt
    46141 gcagagaaaa tagcaatgcg ctattgataa aaatatg
//
LOCUS       DAPGUL010000024        44955 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.024, whole genome shotgun sequence.
ACCESSION   DAPGUL010000024 DAPGUL010000000
VERSION     DAPGUL010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 44955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44955
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.024"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..476)
                     /locus_tag="RHX21_001495"
     CDS             complement(<1..476)
                     /locus_tag="RHX21_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HDV1986704.1"
                     /translation="MQDIQQETLNECTKTEQSALIVLWEIDLTEVGGDHYFFCNEQNE
                     KGEPVTWQGRQYQAYPIQGSGFEMNGKGASARPTLKVSNLHGMVTGMAEDLQSLVGGT
                     VVRRKVYARFLDAVNFVNGNSDADPEQEVISRWRIEQCSELSAVSASFVLSTPTET"
     gene            complement(476..832)
                     /locus_tag="RHX21_001496"
     CDS             complement(476..832)
                     /locus_tag="RHX21_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001347380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV1986705.1"
                     /translation="MEDCTVPEPEVFNWIPREGMETTRKPSVITVKFGDGYEQRRAGG
                     LNADLKTFKPVFRVTDEYSRAALDSFLSRHAGIRAFLWRPPKHNRTVRVVCREWSISD
                     NAMYTDFNCTFEEVTH"
     gene            complement(810..4037)
                     /locus_tag="RHX21_001497"
     CDS             complement(810..4037)
                     /locus_tag="RHX21_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001463338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDV1986706.1"
                     /translation="MATLRELIIKISANSRSFQSEISRASRMGQDYYRTMQNGGRQSA
                     AASREMRRALAEVTDQINTAKSSALNMAGAFAGAFATGHLISLADEWNSVNARLKQAS
                     QSSDDFQVSQRELMAISQRTGTAFSDNASLFARSAASMREYGYSSEEVLKVTEAISTG
                     LKLSGASTAEASSVITQFSQALAQGVLRGEEFNSVNESGDRVIRALAAGMGVARKDLK
                     AMADNGKLTADKVVPALISQLGALRDEYAAMPDTVSSSATKVENAFMAWVGGANEASG
                     VTKTLSGVLNGLAGNIDTVATAAGALVAVGVARYFGNMASSAGSATAGLITAARNEVA
                     LAEAQLRGTQIATARARAAVYRAQQAVVAARGTERQAAAEAKLTAAQASLTRNIAART
                     AAQTTLNTVTSVGSRLLSGALGLVGGVPGLVMLGATAWYTMYQNQEQARESARQYAAT
                     IDEIRQKTSAMSLPEASDNEEKTRQALDEQNRLIDEQKSKIKSLQEKIAGYQYVLANP
                     GWTTDNGFMINHMTSVKTVTEGLAEATNQLAVEQSRLTQMQGKAQSIQDVLAGLEERR
                     VALIRQQAAEQNKAYQSLLIMNGQHTEFNRLLGLGNELLQQRQGLVNVPLRLPQATLD
                     DKQQTALNNSERELALSRLKGEARERARLGYAADDLGFVGEAYQTARQNYINNSLDAW
                     RNNQANKPKAHKKTEAEKTEDIYKRLIKQQKEQIALAGQNTELAKMKYQVSQGELSTL
                     SEAQKKTLLQNAALIDQKKIREQLAAYESSLADSNASTRASNDAQLLGYGEGSRMRER
                     LQEMWSIRHEFEQKNNELLRQYQAGEIEEALWKQEKELNKKYLEERLSDQQDYYAKAD
                     ALRNNWNAGLQEGLTNWADSATDYASQAADAVVSTMDGLVSNISDALAGNVVDWRNWG
                     SSILQEVSKILMNAAIVNGLKSLSGAGGWLGTVGGWISGAVANAKGGVYTSANLSAYS
                     NTIVDTPTYFAFAKGAGLMGEAGPEAIMPLTRAADGSLGVRAIGNVNSGGGFVYSPVY
                     HISIQNQGSNGEIDARSARGLVDLIDSRVVSIMQSSRRDGGLYSA"
     gene            complement(4084..4362)
                     /locus_tag="RHX21_001498"
     CDS             complement(4084..4362)
                     /locus_tag="RHX21_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004967194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4035 domain-containing protein"
                     /protein_id="HDV1986707.1"
                     /translation="MMLALRMGRTLSELRREMSASEIMMWAEFDRFSPLGDERADFRA
                     AQIVSAVYGAQGVKVSLNDALLQWEKEQTEGVSDPFAGLEKALLIVSQ"
     gene            complement(4386..4757)
                     /locus_tag="RHX21_001499"
     CDS             complement(4386..4757)
                     /locus_tag="RHX21_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly chaperone"
                     /protein_id="HDV1986708.1"
                     /translation="MTKNIRNLALATMSGFRHKTVDVPEWEGATVVLREPSAEAWLRW
                     QEIVKAKDNETPLSVAERARRNLEADVELFIDVLCDTGLQPVFSEDDREQVIAVYGPV
                     HARLLRQSLELISDAGEVKKK"
     gene            complement(4772..5476)
                     /locus_tag="RHX21_001500"
     CDS             complement(4772..5476)
                     /locus_tag="RHX21_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001735010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunoglobulin domain-containing protein"
                     /protein_id="HDV1986709.1"
                     /translation="MSSNFERSQLTKIMISSAPVTAETLDSASYLGLSCTIKEVQFTA
                     GQKQDIDVTTLCSVEQENINGLGAASEISMSGNFYLNAAQNALRSAYDNDTTYGFKVI
                     FPSGNGFTFMAEVRQHTWSAGTNGVVAATFSLRLKGKPVLTTASLKVKVDLKSTLRVA
                     SGAKLEMAVEAAGGVPPYSYVWKKGGSPVSGQTAATFSKASASSGDAGAYTCEISDSA
                     SPVNKVTSTSCTVTVS"
     gene            complement(5536..5880)
                     /locus_tag="RHX21_001501"
     CDS             complement(5536..5880)
                     /locus_tag="RHX21_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3168 domain-containing protein"
                     /protein_id="HDV1986710.1"
                     /translation="MREATLYSLLSQLAGGQVYPYVVPLTEGKPAVSPPWLVFSVVSD
                     TASDVLDGQAESRITVQIDVWATVPDDADNIREQALDAVRKLAPSVISKTQGYDPDSR
                     LSRATLEFQVIA"
     gene            complement(5877..6326)
                     /locus_tag="RHX21_001502"
     CDS             complement(5877..6326)
                     /locus_tag="RHX21_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HDV1986711.1"
                     /translation="MMDFSLDFSGLADIARDLETLSRAENNKVLRDATRAGAEVMRDA
                     VVERAPERTGKLKKNVVVLTQRSKRRGEIISGVHIRGRNLRTGNSDNSMKASDPRNAF
                     YWRFVELGTINMPAHPFIRPAFDTTEELAAQVAIQRMNQAIDEVLSK"
     gene            complement(6323..6661)
                     /locus_tag="RHX21_001503"
     CDS             complement(6323..6661)
                     /locus_tag="RHX21_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001147815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HDV1986712.1"
                     /translation="MQAGRLRDRVIILNVTTARSPSGHPVETVTEGATVWAEVKGISG
                     REIISGGAETAQATVRVWMRFRRDVTATSRLKVLTGAFKGAILGIEGPPIPDARATRL
                     EILCSLKGNV"
     gene            complement(6670..6987)
                     /locus_tag="RHX21_001504"
     CDS             complement(6670..6987)
                     /locus_tag="RHX21_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HDV1986713.1"
                     /translation="MAAIVEKLRAQCRIDTDDATDDELLMLYFRAACRKAENFINRKL
                     YEETVPEGDPEGVLIADDVLLALMLLVGHWHENRENSSDVSKAPVPFGFSSLLEPYRF
                     IPL"
     gene            complement(7064..8281)
                     /locus_tag="RHX21_001505"
     CDS             complement(7064..8281)
                     /locus_tag="RHX21_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001566770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HDV1986714.1"
                     /translation="MKLHEMKQKRNTIAKDMRALHEKIGDNAWTDEQRAEWNRAKAEL
                     DALDEQIAREEELRRQDQAYVDESGPEERQNNEAENGKKAVEEKRAAAFNRFLRAGFA
                     ELNAEERNLMRELRAQSVTTDSQGGYTVPTQMRNKIIDTMKAYGGIASVAQLLTTSTG
                     QDITWSTSDGTTEEGELLAENTAATEQDVTFGTAILGAKKLSSKIIRVSNELLQDSGV
                     DIESYLANRIAQRIGRGEAKYLVQGTGTGSPLQPKGLAASVTGTIQTAASAAFTWKEM
                     NALKHAIDPAYRGGPKYRWAFNDATLQTIEEMEDGQKRPLWLPDIAGGTPATVLGIPY
                     VIDQAIDGIGTGKKFIFLGDFNRFIIRRVTYMELKRLVERYAEFDQVAFLAFHRFDCV
                     LEDVAAIKALTGK"
     gene            complement(8296..8895)
                     /locus_tag="RHX21_001506"
     CDS             complement(8296..8895)
                     /locus_tag="RHX21_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004104236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HDV1986715.1"
                     /translation="MNDRETRCYSGEVRAEQYDNAPTHILGYGSVFNSRSEPLWGFRE
                     IIKPGAFDDVLNDDVRGLFNHDPNFILGRSSAGTLSLSVDERGLRYDIVAPDTPTICD
                     LVLSPMLRGDINQSSFAFRVARDGESWYEDDEGIVIREITRISRLYDVSPVTYPAYQD
                     ADSGVRSMKAWQEARASGALKKAVNERMARERLLTLLNA"
     gene            complement(8888..10114)
                     /locus_tag="RHX21_001507"
     CDS             complement(8888..10114)
                     /locus_tag="RHX21_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000923128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDV1986716.1"
                     /translation="MLLDALFRSEPLENPSVPVTGEAAETDNIFARDVYVSPETSMKL
                     AAVYACIYVISSSVAQMPLHVMRKTNEHVQPARDHPLFWLVHDEPNAWQTSYKWRELK
                     QRHVLGWGNGYTWVKRNRRGEVTSLECCMPWETTLLNTGGRHTYGVYNEEGAFAVSPD
                     DMIHIRALGNNQKMGLSPIMQHAETIGMGMSGQQYTSAFFNGNARPAGIISVKNELNE
                     QSWGRLKNMWQRAVTALRSQENKTMLLPAQLDYRALTVSPVDAQIIDMTKLNRSMIAG
                     IFNVPAHMINDLEKATFSNITQQAIQFVRYTMMPWVANWEQELNRRLFTRTERAAGYY
                     VRFNLTGLLRGTPQERAQFYHFAITDGWMSRNEARAFEDMNPVDGLDEMLVSVNAANP
                     LNNFKDTKGKEEKNDE"
     gene            complement(10104..10265)
                     /locus_tag="RHX21_001508"
     CDS             complement(10104..10265)
                     /locus_tag="RHX21_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000811487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986717.1"
                     /translation="MKQLITDMTGLIGFGLLTAGVYLYAGLPASLMLSGCLLLLYALV
                     VSMRRKHAS"
     gene            complement(10262..12019)
                     /locus_tag="RHX21_001509"
     CDS             complement(10262..12019)
                     /locus_tag="RHX21_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016240704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HDV1986718.1"
                     /translation="MAKVADGIRYAERVVAGEIVAGEFVRLACQRFLDDLKYGEERGI
                     YFSEPRAQHILNFYKFVPHVKGALAGQPIELMDWHVFILINIFGFVIPLVNEETGEVV
                     MRSDGSGRPVMVRRFRTAYNEVARKNAKSTLSSGIGLYMTGADGEGGAEVYSAATTRD
                     QARIVFEDAKNMVRKARSTLGRLFDFNKLAIYQEQSASKFEPLSSDANNLDGLNIHCA
                     IIDELHAHKTRDVWDVLETATGARLQSLLFGITTAGFNKEGICYEQRDYAIKVLRGYN
                     SDVEGAVKDDSYFAIIYTLDEGDDPFDETVWQKANPGLGICKRWDDLRRLAKKAKEQV
                     SARVNFFTKHMNVWVTAESAWMDMIKWEKCEYIAPQHELKTYPMWVGVDLAHKIDICA
                     AAKLWRTDNGHVHADFKFWLPEGRLERCSRQQAELYRKWAEMDKLILTDGDVIDHAQI
                     KSDLLEWIGGENLRELGFDPWSAMQFSLALAEEGIPLVEVPQTVRNLSEAMKETESLV
                     YAGRFHHSNHPVMNWMMSNVTVKPDKNDNIFPNKSTPEAKIDGPVALFTAMSRFLVNG
                     GGVNDFLSTLDPDEDLLIL"
     gene            complement(12019..12501)
                     /locus_tag="RHX21_001510"
     CDS             complement(12019..12501)
                     /locus_tag="RHX21_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HDV1986719.1"
                     /translation="MSGPPKTPPRLHLIRGNPSKRPVKDSKKTAKKDEKGLPKIPQHL
                     GAQGKYWFRRMAEELNAEGIISQLDARALELLVEAYTEYRHHCEILDVEGYTYRTETQ
                     NGDVLIKAHPAAAMKADAWKRIRAMLAEFGMSPASRAKVNTAGPDDVDPLAELLKARD
                     "
     gene            complement(12649..12999)
                     /locus_tag="RHX21_001511"
     CDS             complement(12649..12999)
                     /locus_tag="RHX21_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001542815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDV1986720.1"
                     /translation="MPSRIPRACRKRGCAGTTTDSSGYCDKHRGEGWVQHQRGLSRHQ
                     RGYGSKWDAIRARILKRDNHLCQNCLRNGRAVEARTVDHIIPKAHGGTDADSNLQSLC
                     WPCHKAKTARERIN"
     gene            complement(13007..13207)
                     /locus_tag="RHX21_001512"
     CDS             complement(13007..13207)
                     /locus_tag="RHX21_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986721.1"
                     /translation="MKFQVAKLYRGKHFAGYGIAVDGELLEGQLSARTESRGGEPPTV
                     TVTFRLTAEHIENQPVIQLNRG"
     gene            13452..13937
                     /locus_tag="RHX21_001513"
     CDS             13452..13937
                     /locus_tag="RHX21_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDV1986722.1"
                     /translation="MPELVDPTDSLISFQYAFSNGLIKPSPCIVHPNMKVLLDDAEGT
                     PRFTYAFFEGENVKGVAIYVPAEFVEGKPCFGVGYAVADEYKAQGIGTQLLIASIEEM
                     QYGFRNSFNEFYVEAIVGVGNQASNKLAAKVLSDTPEPGTDSYSGKPINQYMKLFKTT
                     K"
     gene            complement(14178..14363)
                     /locus_tag="RHX21_001514"
     CDS             complement(14178..14363)
                     /locus_tag="RHX21_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rz1 family lipoprotein"
                     /protein_id="HDV1986723.1"
                     /translation="MRKLKMKLCALMLPLVVSACGSMPVAPQPCVKPPDPPAWIMQPA
                     PDWQTPLNGIISPSENG"
     gene            complement(14580..15113)
                     /locus_tag="RHX21_001515"
     CDS             complement(14580..15113)
                     /locus_tag="RHX21_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706619.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HDV1986724.1"
                     /translation="MSAKIKYGLSAAVLALIAAGASAPQILDQFLDEKEGNHTTAYRD
                     GSGIWTICRGATMVDGKPVIPGMKLSKEKCDQVNAIERDKALAWVERNIKVPLTEPQK
                     AGIASFCPYNIGPGKCFPSTFYKRLNAGDRKGACEAIRWWIKDGGRDCRIRSNNCYGQ
                     VIRRDQESALACWGIDQ"
     gene            complement(15169..15483)
                     /locus_tag="RHX21_001516"
     CDS             complement(15169..15483)
                     /locus_tag="RHX21_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1327 domain-containing protein"
                     /protein_id="HDV1986725.1"
                     /translation="MTQNYELIVKGIRNFENKVTVTLALRDKKRFDGEIFGLDISLDR
                     VEGAALEFYEAAARRSIRQVFLDVAAGLCEGDELLPETRPCSEARYTIKINSSDNSIT
                     GC"
     gene            complement(15488..15703)
                     /locus_tag="RHX21_001517"
     CDS             complement(15488..15703)
                     /locus_tag="RHX21_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II holin family protein"
                     /protein_id="HDV1986726.1"
                     /translation="MKSMDKISTGIAYGTSAGSAGYWFLQWLDQVSPSQWAAIGVLGS
                     LVLGFLTYLTNLYFKIREDKRKAARGE"
     gene            complement(15998..16072)
                     /locus_tag="RHX21_001518"
     tRNA            complement(15998..16072)
                     /locus_tag="RHX21_001518"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16037..16039),aa:Gly,seq:tcc)
     gene            complement(16076..16151)
                     /locus_tag="RHX21_001519"
     tRNA            complement(16076..16151)
                     /locus_tag="RHX21_001519"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16116..16118),aa:Thr,seq:tgt)
     gene            complement(16154..16230)
                     /locus_tag="RHX21_001520"
     tRNA            complement(16154..16230)
                     /locus_tag="RHX21_001520"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16194..16196),aa:Lys,seq:ttt)
     gene            complement(16232..16307)
                     /locus_tag="RHX21_001521"
     tRNA            complement(16232..16307)
                     /locus_tag="RHX21_001521"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(16272..16274),aa:Ile,seq:cat)
     gene            complement(16502..17191)
                     /locus_tag="RHX21_001522"
     CDS             complement(16502..17191)
                     /locus_tag="RHX21_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antiterminator"
                     /protein_id="HDV1986727.1"
                     /translation="MNNQYLQFVREQLIIATADLSGATKGQLEAWQENAMFDTGRYRR
                     KKIRYRDEVTGRMITRDSPPIPGKQSLAKGSSIALVSQVEFSTSSWRRAVLSLEEHHK
                     AWLLWCYSGSICWEYQIAITQWAWNEFNTQSGTRKIAGKTQERLKKLIWLAAQALKAE
                     LFGGEGYEYQELALLAGVTTKNWSKTFTRHWVAMKHIFHRLDSEALLFVMRTRSKQKA
                     AFSKQSVAKVD"
     gene            complement(17188..17547)
                     /locus_tag="RHX21_001523"
     CDS             complement(17188..17547)
                     /locus_tag="RHX21_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDV1986728.1"
                     /translation="MRIEFVLPYPPTVNTYWRRRGNTYFVSKVGERYRRDVALIVRQQ
                     RLKLNLSGRLAIKIIAEPPDKRRRDLDNILKAPLDALTHAGLLIDDEQFDEINIVRGL
                     PVPGGRLGIKITELECA"
     gene            complement(17560..18609)
                     /locus_tag="RHX21_001524"
     CDS             complement(17560..18609)
                     /locus_tag="RHX21_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF968 domain-containing protein"
                     /protein_id="HDV1986729.1"
                     /translation="MRILLRPVLVPELGLVVLRPGRESMQVFHNPRVLVEPEPKSMRG
                     LPSGVVPAVRQPLAEDKSLLPFFSDERVIRAAGGAGALSDWLLRHVKSCQWPHGDYHH
                     SEIVIHRYGTSAMVLCWHCDNQLRDQTSESLGQLAHQNLSAWMIDVIRHAMNGTQERE
                     LSLAELSWWAVCNQVADALPEAVLRRSLGVRAEKIRSLYRESDIVPGEQTATSILKQR
                     TKNLAPLPHAHQQQNPPQEKTVVCITVDPESPESFMRRPKRRRWLNEKYTRWVKTQPC
                     ACCGQPADDPHHLIGHGQGGMGTKAHDIFTLPLCREHHNELHADPLAFEEKHGSQVDL
                     IFRFLDHAFATGVLG"
     gene            complement(18611..18889)
                     /locus_tag="RHX21_001525"
     CDS             complement(18611..18889)
                     /locus_tag="RHX21_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986730.1"
                     /translation="MAHDTKLHNSDDSAVFASRHGRRSRTFKSDWFQHDPCTEEQAEW
                     LIHNYRRRGYEIKKALSLDYRHWIIYVRLPYSERPPRPSRTYQQRIWR"
     gene            complement(19186..19578)
                     /locus_tag="RHX21_001526"
     CDS             complement(19186..19578)
                     /locus_tag="RHX21_001526"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986731.1"
                     /translation="MKKLVLVAGVMIATVMLGGCAAKIDPALKAEAMKPLTCNDEKQC
                     DFYWKRAQFWLANNSSWKIQTATDTLISTYNPSPNSPFLAYQVSKMPNEDGSSRIFIK
                     PFCDNMFGCQPNPYQAVVSFKNFVKTGQ"
     gene            complement(19722..19877)
                     /gene="hokD"
                     /locus_tag="RHX21_001527"
     CDS             complement(19722..19877)
                     /gene="hokD"
                     /locus_tag="RHX21_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokD"
                     /protein_id="HDV1986732.1"
                     /translation="MKQQKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVF
                     TAYEPEE"
     gene            complement(20114..20779)
                     /locus_tag="RHX21_001528"
     CDS             complement(20114..20779)
                     /locus_tag="RHX21_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016235606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HDV1986733.1"
                     /translation="MTIADFKRPKLELPNGANKLLLHSCCAPCSGEVMEALQASGIDY
                     TIFFYNPNIHPQKEYLIRKDENIRFAEQHGVPFIDADYDTDNWFERAKGMEWEPERGI
                     RCTMCFDMRFERTALYAAENGFSVISSSLGISRWKNMQQVNECGRRAVAHYPGMVYWD
                     YNWRKQGGSSRMIEISKREKFYQQEYCGCVYSLRDTNLHRKSQGRPLIKIGQLHYGKE
                     EKE"
     gene            complement(20954..21379)
                     /locus_tag="RHX21_001529"
     CDS             complement(20954..21379)
                     /locus_tag="RHX21_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016232644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF977 family protein"
                     /protein_id="HDV1986734.1"
                     /translation="MAKVFTQEEREKIKGQVVELVRLSGRETLRQLEARTGATRYLMS
                     VLARELVASGDVYNSGYGLFPSEQARKDWQNARKKLSRAKVKKPAVVDPDLIWSLPDG
                     EIRRYDRRLNIICRECRKSEAMQRVLAFYQGNVRYFRRY"
     gene            complement(21395..22165)
                     /locus_tag="RHX21_001530"
     CDS             complement(21395..22165)
                     /locus_tag="RHX21_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1627 domain-containing protein"
                     /protein_id="HDV1986735.1"
                     /translation="METVSDALKALKKASSHVVAARLGISREEAVNELWELKRKGVVD
                     KTGHTWFLAGEGESRVTEERPVKSEAQDMLTGEVEQKVTADMMIEFIGQDGAKTCEEL
                     AGKFGVSTRKVASTLAVVTATGRLARVNQNGKFRYCMPGDNLPAEPKAALVTESDGKA
                     FPQPAGAALPVREAATQEEIKTETVADIVQPLPSFTETQADELIFPSLRRANLALRRA
                     KSDVQKWERVCAALRELNKHRDIVRQITDSSRRVVSEK"
     gene            complement(22187..22933)
                     /locus_tag="RHX21_001531"
     CDS             complement(22187..22933)
                     /locus_tag="RHX21_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDV1986736.1"
                     /translation="MKNIAAVGVLERIRRLAPQGSVPPYRTVEEWREWQLAEGRKRSE
                     EINRQNRQLRVEKILNRSGIQPLHSKCSFANYQVQNDGQKYALSQAKSIADELMTGCT
                     NFVFSGKTGTGKNHLAAAMGNRLMVKGRSVIIVTVSDVMSVLHDSYDNGKSGEKFLQE
                     LCGVDLLVLDEIGVQRETKNEQVVLHQIIDRRTASLCSVGMLTNLNHAAMSTLLGERI
                     MDRMTMNGGRWVTFNWDSWRPNVSNMRVVK"
     gene            complement(22940..23902)
                     /locus_tag="RHX21_001532"
     CDS             complement(22940..23902)
                     /locus_tag="RHX21_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310303.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDV1986737.1"
                     /translation="MSSKLHGLVWEGCAFTGMILSRVAVMARLADYSNDEGVSWPAIE
                     TIRRQIGARSESTVKSAIAELAKEGWLTKEERKVGGRNVSNIYRLNVEKLEAAAAAAR
                     ESYKPKRKISPAKNDPLTVDPSNIDPSTVDPSNFDGSTVDKKLPIRGAMIDPDPSVLK
                     PDPSDKRSSCPDASQPDPQTAEQDFLTRHPDAVVFSAKKRQWGSQEDLVCAQWIWGRI
                     VSLYEQAASYDGEITRPKEPNWTAWANDVRTMRMLDGRTHRQICEMFGRLQRDSFWVK
                     NIMSPAKLREKWDELVIRLGRSPAQRCVNHISEPDTEIPPGFRG"
     gene            complement(23925..24350)
                     /locus_tag="RHX21_001533"
     CDS             complement(23925..24350)
                     /locus_tag="RHX21_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HDV1986738.1"
                     /translation="MKIKHEHIRMAMNAWARPDGEKVPAAGITQAYFELGMTFPELYD
                     DSHPEALARNTQKIFRWVEKDTPDAVEKMQALLPAIEKAMPPLLVARMRSHSSEYYRE
                     IVERRDRLVKDVDDFVASAVVLYDQMNRGGPAGNAVVMH"
     gene            complement(24334..24615)
                     /locus_tag="RHX21_001534"
     CDS             complement(24334..24615)
                     /locus_tag="RHX21_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDV1986739.1"
                     /translation="MEELRIFLNSLSSDEQRMFACECGTSIGYLRKALSKGQVLGASL
                     CVLIERASNGEVTRQQLRPFDWMNIWPELEDTKTLTQPLSRSLIHENQA"
     gene            24716..25135
                     /locus_tag="RHX21_001535"
     CDS             24716..25135
                     /locus_tag="RHX21_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986740.1"
                     /translation="MDKYEFRRQQLIKIRDEKCDGKAVNVARKIGREPSYVSRMLYPE
                     GKKGKKRIADDMVEIIEESFGLPRGWMDGIVSSSTNTASSYETRVLTPRQRIFLDLLD
                     ELPESEADKLLKTLEEKKQYYNMIYEEIRKKKAQNAS"
     gene            25462..25761
                     /locus_tag="RHX21_001536"
     CDS             25462..25761
                     /locus_tag="RHX21_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986741.1"
                     /translation="MALYIDISAIAGQVRVIRAVTKRYASLFQKVSGECTEDIVNDFV
                     IELRGLIFSYKVTTIFADGSRETVRALRLKGCVKDFATTFWARKLDCIHNQFPLE"
     gene            25833..26051
                     /locus_tag="RHX21_001537"
     CDS             25833..26051
                     /locus_tag="RHX21_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986742.1"
                     /translation="MQKREPVIIAPDYTDDELYEWMRQKINAAQDLKWANEARAKQAE
                     NLSALEQDITRLEKAAALSIARMITYPR"
     gene            26074..26403
                     /locus_tag="RHX21_001538"
     CDS             26074..26403
                     /locus_tag="RHX21_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001387734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986743.1"
                     /translation="MEFKDLPMQFQEMAANIVRSQLATLDLSTVEKETIDTISGNVRR
                     AFIGLYEEKQLSDNQDLHEKYFLDLMDIINKGFGLLMEKKGIRIEPLENCFVTRSINS
                     FDSKQEN"
     gene            complement(26372..26647)
                     /locus_tag="RHX21_001539"
     CDS             complement(26372..26647)
                     /locus_tag="RHX21_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000505224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986744.1"
                     /translation="MGFDVNETLNSLIRKINDFDKTLQHAAARSDITLLAISYLASAM
                     NKDETVRKNLVDYIDSLQPGTFNPESFNHEKEHVKSVINSLVLNQKN"
     gene            27214..27435
                     /gene="kil"
                     /locus_tag="RHX21_001540"
     CDS             27214..27435
                     /gene="kil"
                     /locus_tag="RHX21_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707273.1"
                     /note="Rac prophage Kil protein; Kil overexpression leads
                     to morphological defects and inhibits cell division;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HDV1986745.1"
                     /translation="MIAHHFGTDEIPRQCVTPGDYVIHKGRTYIASVNNIKKQRLYIR
                     DFSTQHCIKETMIKVFLGRDGLPVKAESW"
     gene            27559..30030
                     /locus_tag="RHX21_001541"
     CDS             27559..30030
                     /locus_tag="RHX21_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease"
                     /protein_id="HDV1986746.1"
                     /translation="MSKVFICAAIPDEQAIKEEGAVAVATAIEAGDERRARAKFTWQF
                     LEQHPAAQDCAYKFLVCEDKPGMARPALDSWDTEYMQENHWDEESASFIPVEPESDPM
                     NVNFDKLSLEVQNAVLVKFGTCENITVDMVISAQELLQEDMATFDGHIVEALMKMPEV
                     NVMYSELKLLAIGWVKHKCNPGAKWPEIQAEMRIWKKRREDERKETGKYTSVVDLARA
                     RANQQHTENSTGKINPVIAATHREYKQTWKTLDDELAYALWPGDVDAGNIDGSIHRWA
                     KNEVIDNDREDWKRISASMRKQPDALRYDRQTIFGLVRERPIDIHKDPVALNKYITEY
                     LTTKGVFEDEGRNQSATDTLSAPVPETDAVETAIPDNEKTECKVEVEPSVEREGPFYF
                     LFTDKDGEKYGRANKLSGLGKALAAGATEITKEEYFARKNGTYSGSQQNTGASDTTAQ
                     PGSVKVTADEVNKIMQAANISQPDADELLAVSRGEFVEGISDPNDPKWVKGIQTRDSV
                     NQNQQETEQNDQKAEQNSPNALQNEPETKQPEPVAQQEVEKVCTACGQTGGGNCPDCG
                     AVMGDATYQETFDEEYQVEVQEDDPEEMEGAEHPHKENTGGNQHHASDNETGETADHS
                     IKVNGHQEITSTSRTCDHLMIDLETMGKNPDAPIISIGAIFFDPQTGDMGPEFSKTID
                     LETAGGVIDRDTIKWWLKQSREAQSAIMTDEIPLDDALLQLREFIDENSGEFFVQVWG
                     NGANFDNTILRRSYERQGIPCPWRYYNDRDVRTIVELGKAIDFDARTAIPFEGERHNA
                     LDDARYQAKYVSVIWQKLIPSQADF"
     gene            30092..30361
                     /locus_tag="RHX21_001542"
     CDS             30092..30361
                     /locus_tag="RHX21_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDV1986747.1"
                     /translation="MSEQYLITLDEWKPKRFSLPITNTTLVKYGKLGYIVPRPQKIRG
                     RWLIDRRAVFVGPGETGIAPEIHTGDDDALKEILTHVTEATKKQH"
     gene            30330..31448
                     /locus_tag="RHX21_001543"
     CDS             30330..31448
                     /locus_tag="RHX21_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase Arm DNA-binding
                     domain-containing protein"
                     /protein_id="HDV1986748.1"
                     /translation="MSPRPRKNSTDVAGLYEKFDRRTGRVYYQYKNPVTGKFHGLGTD
                     KCKAEKIASTANQRIAAAEAEYFMRKIDESPSATKRRGIRLKAWVDRYLKIQDTRLKN
                     GDIAATTHKEKTRMAAYLVSRLGNHPLKELEVRDFALILDEWLDKDMVSTARVNRGLW
                     VDIYKEAQHAGEVPPGWNPPEATRKPIPKVTRARLTMEDWQKIYNATPEKHFIRNAML
                     LAIVTGQRRDDICHMRFSDVWNEHLHITQGKTGMRLALPLTLRCDAIGITLKEVIDGC
                     RDRILSPYLIHSRHQKQPKPMSKDNLSDYFAKARDLAGIIPPAGKTPPTFHEQRSLSE
                     RLYRAQGIDTKTLLGHKVQATTDRYNDTRGQEWVKLVI"
     gene            31615..32409
                     /gene="potC"
                     /locus_tag="RHX21_001544"
     CDS             31615..32409
                     /gene="potC"
                     /locus_tag="RHX21_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter permease
                     PotC"
                     /protein_id="HDV1986749.1"
                     /translation="MIGRLLRGGFMTAIYAYLYIPIIILIVNSFNSSRFGINWQGFTT
                     KWYSLLMNNDSLLQAAQHSLTMAVFSATFATLIGSLTAVALYRYRFRGKPFVSGMLFV
                     VMMSPDIVMAISLLVLFMLLGIQLGFWSLLFSHITFCLPFVVVTVYSRLKGFDVRMLE
                     AAKDLGASEFTILRKIILPLAMPAVAAGWVLSFTLSMDDVVVSSFVTGPSYEILPLKI
                     YSMVKVGVSPEVNALATILLVLSLVMVIASQLIARDKTKGNTGDVK"
     gene            32406..33452
                     /gene="potD"
                     /locus_tag="RHX21_001545"
     CDS             32406..33452
                     /gene="potD"
                     /locus_tag="RHX21_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein PotD"
                     /protein_id="HDV1986750.1"
                     /translation="MKKWSRHLLAAGALALGMSAAHADDNNTLYFYNWTEYVPPGLLE
                     QFTKETGIKVIYSTYESNETMYAKLKTYKDGAYDLVVPSTYYVDKMRKEGMIQKIDKS
                     KLTNFSNLDPDMLNKPFDPNNDYSIPYIWGATAIGVNGDAVDPKSVTSWADLWKPEYK
                     GSLLLTDDAREVFQMALRKLGYSGNTTDPKEIEAAYNELKKLMPNVAAFNSDNPANPY
                     MEGEVNLGMIWNGSAFVARQAGTPIDVVWPKEGGIFWMDSLAIPANAKNKEGALKLIN
                     FLLRPDVAKQVAETIGYPTPNLAARKLLSPEVANDKTLYPDAETIKNGEWQNDVGAAS
                     SIYEEYYQKLKAGR"
     gene            33510..33971
                     /locus_tag="RHX21_001546"
     CDS             33510..33971
                     /locus_tag="RHX21_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001460774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3592 domain-containing protein"
                     /protein_id="HDV1986751.1"
                     /translation="MSQDSKVLSRAFLGIGLILLVISAIIFYYHFTFTKSAVHTEGII
                     VDAVWYNNHSNDVDDNGSWYPVVAFRPTPDYTLIFNSNIGSDFYEDSEGDRVNVYYPP
                     GHPEQAEINNPWVNFFKWGFVGIAGIIFGSVGLIITLPSTKKSRRKRKSRP"
     gene            33968..34306
                     /locus_tag="RHX21_001547"
     CDS             33968..34306
                     /locus_tag="RHX21_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986752.1"
                     /translation="MKKFIILLSLLILLPLVATSKPLIPIMKTLFTDVTGTVPDAEEI
                     ARKAELFRQQTGIAPFIVILPDINNEASLRQNGKAMLAHASSSLSNVKGSVLLLFTTR
                     EPRLIMITNG"
     gene            34409..34756
                     /locus_tag="RHX21_001548"
     CDS             34409..34756
                     /locus_tag="RHX21_001548"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986753.1"
                     /translation="MAVLQAQILKQPTPPLTYYPHPGQQHENAPPGSTNTLGFIAWAA
                     TFILFSWIFCYTTRFIYALKFAVAMTIANMGYQALCLYIDNSFAITRISPLWAGLIGV
                     CTFIAALLLTSKR"
     gene            complement(34895..35716)
                     /gene="cobB"
                     /locus_tag="RHX21_001549"
     CDS             complement(34895..35716)
                     /gene="cobB"
                     /locus_tag="RHX21_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HDV1986754.1"
                     /translation="MLSRRGHRLSRFRKNKRRLRERLRQRIFFRDKVVPEAMEKPRVL
                     VLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFDRDPELVQAFYNARRRQLQQP
                     EIQPNAAHLALAKLQDALGDRFLLVTQNIDNLHERAGNTNVIHMHGELLKVRCSQSGQ
                     VLDWTGDVTPEDKCHCCQFPAPLRPHVVWFGEMPLGMDEIYMALSMADIFIAIGTSGH
                     VYPAAGFVHEAKLHGAHTVELNLEPSQVGNEFAEKYYGPASQVVPEFVEKLLKGL"
     gene            complement(35732..36643)
                     /gene="nagK"
                     /locus_tag="RHX21_001550"
     CDS             complement(35732..36643)
                     /gene="nagK"
                     /locus_tag="RHX21_001550"
                     /EC_number="2.7.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HDV1986755.1"
                     /translation="MYYGFDIGGTKIALGVFDSGRQLQWEKRVPTPRDSYDAFLDAVC
                     ELVAEADQRFGCKGSVGIGIPGMPETEDGTLYAANVPAASGKPLRADLSARLDRDVRL
                     DNDANCFALSEAWDDEFTQYPLVMGLILGTGVGGRLIFNGKPITGKSYITGEFGHMRL
                     PVDALTMMGLDFPLRRCGCGQHGCIENYLSGRGFAWLYQHYYHQPLQAPEIIALYDQG
                     DEQARAHVERYLDLLAVCLGNILTIVDPDLVVIGGGLSNFPAITTQLADRLPRHLLPV
                     ARVPRIERARHGDAGGMRGAAFLHLTD"
     gene            complement(36672..37916)
                     /gene="lolE"
                     /locus_tag="RHX21_001551"
     CDS             complement(36672..37916)
                     /gene="lolE"
                     /locus_tag="RHX21_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit LolE"
                     /protein_id="HDV1986756.1"
                     /translation="MAMPLSLLIGLRFSRGRRRGGMVSLISVISTIGIALGVAVLIVG
                     LSAMNGFERELNNRILAVVPHGEIEAVDQPWTNWQEALDHVQKVPGIAAAAPYINFTG
                     LVESGVNLRAIQVKGVNPQQEQRLSALPSFVQGDAWRNFKAGEQQIIIGKGVADALKV
                     KQGDWVSIMIPNSNPEHKLMQPKRVRLHVAGILQLSGQLDHSFAMIPLADAQQYLDMG
                     SSVSGIALKMTDVFNANKLVRDAGEVTNSYVYIKSWIGTYGYMYRDIQMIRAIMYLAM
                     VLVIGVACFNIVSTLVMAVKDKSGDIAVLRTLGAKDGLIRAIFVWYGLLAGLFGSLCG
                     VIIGVVVSLQLTPIIEWIEKLIGHQFLSSDIYFIDFLPSELHWLDVFYVLVTALLLSL
                     LASWYPARRASNIDPARVLSGQ"
     gene            complement(37916..38617)
                     /gene="lolD"
                     /locus_tag="RHX21_001552"
     CDS             complement(37916..38617)
                     /gene="lolD"
                     /locus_tag="RHX21_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415635.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter
                     ATP-binding protein LolD"
                     /protein_id="HDV1986757.1"
                     /translation="MNKILLQCDNLCKRYQEGSVQTDVLHNVSFSVGEGEMMAIVGSS
                     GSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAELRNQKLGFIYQFHHLLPDF
                     TALENVAMPLLIGKKKPAEINSRALEMLKAVGLDHRANHRPSELSGGERQRVAIARAL
                     VNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQLEM
                     RDGRLTAELSLMGAE"
     gene            complement(38610..39809)
                     /gene="lolC"
                     /locus_tag="RHX21_001553"
     CDS             complement(38610..39809)
                     /gene="lolC"
                     /locus_tag="RHX21_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004976588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit LolC"
                     /protein_id="HDV1986758.1"
                     /translation="MYQPVALFIGLRYMRGRAADRFGRFVSWLSTIGITLGVMALVTV
                     LSVMNGFERELQNNILGLMPQAILSSEHGSLNPQQLPETAVKLDGVNRVAPITTGDVV
                     LQSARSVAVGVMLGIDPAQKDPLTPYLVNVKQTDLEPGKYNVILGEQLASQLGVNRGD
                     QIRVMVPSASQFTPMGRIPSQRLFNVIGTFAANSEVDGYEMLVNIEDASRLMRYPAGN
                     ITGWRLWLDEPLKVDSLSQQKLPEGSKWQDWRDRKGELFQAVRMEKNMMGLLLSLIVA
                     VAAFNIITSLGLMVMEKQGEVAILQTQGLTPRQIMMVFMVQGASAGIIGAILGAALGA
                     LLASQLNNLMPIIGVLLDGAALPVAIEPLQVIVIALVAMAIALLSTLYPSWRAAATQP
                     AEALRYE"
     gene            40071..41144
                     /locus_tag="RHX21_001554"
     CDS             40071..41144
                     /locus_tag="RHX21_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HDV1986759.1"
                     /translation="MKQKELWINQIKGLCICLVVIYHSVITFYPHLTTFQHPLSEVLS
                     KCWIYFNLYLAPFRMPVFFFISGYLIRRYIDSVPWGNCLDKRIWSIFWVLALWGVVQW
                     LALSALNQWLAPERDLSNASNAAYADSTGEFLHGMITASTSLWYLYALIVYFVVCKIF
                     SRLALPLFALFVLLSVAVNFVPTPWWGMNSVIRNLPYYSLGAWFGATLMTCVKEVPLR
                     RHLLMASLLTVLAVGAWLFTISLLLSLVSIVVIMKLFYQYEQQFGMRSTSLLNVIGSN
                     TIAIYTTHRILVEIFSLTLLAQMNAARWSPQVELTLLLVYPFVSLFICTVAGLLVRKL
                     SQRAFSDLLFSPPSLPAAVSYSR"
     gene            41272..44718
                     /gene="mfd"
                     /locus_tag="RHX21_001555"
     CDS             41272..44718
                     /gene="mfd"
                     /locus_tag="RHX21_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HDV1986760.1"
                     /translation="MPEQYRYTLPVKAGEQRLLGELTGAACATLVAEIAERHAGPVVL
                     IAPDMQNALRLHDEISQFTDQMVMNLADWETLPYDSFSPHQDIISSRLSTLYQLPTMQ
                     RGVLIVPVNTLMQRVCPHSFLHGHALVMKKGQRLSRDALRTQLDSAGYRHVDQVMEHG
                     EYATRGALLDLFPMGSELPYRLDFFDDEIDSLRVFDVDSQRTLEEVEAINLLPAHEFP
                     TDKAAIELFRSQWRDTFEVKRDPEHIYQQVSKGTLPAGIEYWQPLFFSEPLPPLFSYF
                     PANTLLVNTGDLETSAERFQADTLARFENRGVDPMRPLLPPQSLWLRVDELFSELKNW
                     PRVQLKTEHLPTKAANANLGFQKLPDLAVQAQQKAPLDALRKFLETFDGPVVFSVESE
                     GRREALGELLARIKIAPQRIMRLDEASDRGRYLMIGAAEHGFVDKVRNLALICESDLL
                     GERVARRRQDSRRTINPDTLIRNLAELHIGQPVVHLEHGVGRYAGMTTLEAGGITGEY
                     LMLTYANDAKLYVPVSSLHLISRYAGGAEENAPLHKLGGDAWSRARQKAAEKVRDVAA
                     ELLDIYAQRAAKEGFAFKHDREQYQLFCDSFPFETTPDQAQAINAVLSDMCQPLAMDR
                     LVCGDVGFGKTEVAMRAAFLAVDNHKQVAVLVPTTLLAQQHYDNFRDRFANWPVRIEM
                     ISRFRSAKEQTQILAEVAEGKIDILIGTHKLLQSDVKFKDLGLLIVDEEHRFGVRHKE
                     RIKAMRANVDILTLTATPIPRTLNMAMSGMRDLSIIATPPARRLAVKTFVREYDSLVV
                     REAILREILRGGQVYYLYNDVENIQKAAERLAELVPEARIAIGHGQMRERELERVMND
                     FHHQRFNVLVCTTIIETGIDIPTANTIIIERADHFGLAQLHQLRGRVGRSHHQAYAWL
                     LTPHPKAMTTDAQKRLEAIASLEDLGAGFALATHDLEIRGAGELLGEEQSGSMETIGF
                     SLYMELLENAVDALKSGREPSLEDLTSQQTEVELRMPSLLPDDFIPDVNTRLSFYKRI
                     ASAKTENELEEIKVELIDRFGLLPDPARTLLDVARLRQQAQKLGIRKLEGNEKGGVIE
                     FAEKNHVNPAWLIGLLQKQPQHYRLDGPTRLKFIQDLSERKTRIEWVRQFMRELEENA
                     IA"
BASE COUNT        11265 a        12004 c        10528 g        11158 t
ORIGIN      
        1 tccgtttccg tcggcgtgga cagtacaaaa gaggcactca ccgcgctcag ttcgctgcac
       61 tgctcgatgc gccagcggct gatcacctcc tgctccggat cggcgtcact gtttccgttg
      121 acgaagttca ccgcatccag aaaacgggcg taaaccttac gccggaccac cgttccgccg
      181 accagactct gcaggtcttc cgccatcccg gtgaccatgc cgtgcagatt agagactttc
      241 agcgttggcc ttgcactggc tcctttgccg ttcatctcaa atccacttcc ctgaatggga
      301 taggcctgat actgccgccc ctgccaggtg actggttcac ctttttcgtt ctgctcatta
      361 cagaagaaat aatgatctcc gccgacctct gtcagatcaa tttcccagag cacgatcagc
      421 gcggattgct ccgttttagt gcactcattg agtgtttcct gctgtatatc ctgcatcagt
      481 gagtgacctc ttcaaaggta cagttaaaat cggtatacat ggcattatcc gaaatgctcc
      541 actccctgca gacaacccgg acagtcctgt tgtgttttgg cggacgccac aaaaaagcac
      601 gaatcccggc atgacgggat aaaaaactgt ccagcgcggc acgggaatat tcatctgtga
      661 cacgaaatac cggtttaaac gttttcagat ccgcattcag accaccagcc cgtctctgtt
      721 catatccgtc accaaacttt accgtaataa ctgatggctt tcgtgtcgtc tccatcccct
      781 cacgggggat ccagttaaaa acttcaggct caggcactgt acaatcctcc atcccgacgc
      841 gatgactgca taattgacac aaccctgctg tcgatcagat ccaccagtcc cctggctgag
      901 cgcgcatcta tctcgccatt gctcccttgg ttctgaatgc tgatgtgata cacgggagaa
      961 taaacaaacc ccccgccact attcacattg ccaatggctc tgaccccaag agagccgtcc
     1021 gctgcccgtg tcagtggcat gatagcttca ggcccggcct cgcccatcag cccggcacct
     1081 ttcgcaaaag caaaatacgt cggtgtatcc acaatagtgt tactgtaagc actcagattt
     1141 gccgatgtgt aaacaccacc ttttgcgttt gccaccgccc ccgaaatcca tccgccgacc
     1201 gtaccaagcc accctccggc accggagagt gacttcagtc cgttaacaat ggccgcattc
     1261 atcagaattt ttgaaacttc ctggagaatt gaactccccc agtttctcca gtccacaaca
     1321 tttccggcca gtgcatcgga aatatttgat accagtccgt ccatagtgga aacgacagca
     1381 tctgccgcct gcgaagcata atcggtggca ctgtctgccc agttggtcag cccctcctgg
     1441 agtcctgcat tccagttatt acgtaaagca tcggcctttg cataataatc ctgctgatcg
     1501 ctgagacgct cttccagata ttttttattc agttctttct cctgtttcca cagggcttct
     1561 tcaatttctc cggcctgata ctgtctcagc agctcgttat ttttctgctc aaactcatgc
     1621 cggatactcc acatttcttg gagtcgttca cgcatccgtg agccttcacc atatcccagt
     1681 aactgcgcgt cgttagacgc ccgggtactg gcattactgt ccgccaggct gctttcatac
     1741 gcagcaagct gctcacgaat ctttttctgg tcgatgagtg ctgcattctg caaaagcgtt
     1801 tttttctgcg cttctgacag ggttgataat tcgccctgac tgacctgata tttcatctta
     1861 gccagttcag tattctgccc tgccagtgct atttgttctt tttgctgttt aatcagccgt
     1921 ttataaatat cttctgtttt ttccgcttcg gtctttttat gcgctttggg tttatttgcc
     1981 tggttatttc gccaggcatc cagtgagtta ttgatataat tctgtctggc tgtctgatac
     2041 gcctctccca caaagccgag atcatccgca gcataaccca agcgggcacg ctcacgggct
     2101 tcccccttca ggcgggacag agccagttcg cgctcgctgt tattcagtgc agtctgctgt
     2161 ttatcatcca gggttgcctg tggtagccgt aacggtacat tcaccagccc ctgtcgctgc
     2221 tgaagtaatt cattaccgag cccgagaagg cgattaaact cggtatgctg cccattcatg
     2281 atcaacaggg actgatacgc tttgttttgt tccgcggcct gttgacggat caacgccacc
     2341 cgtcgctcct ccagcccggc aagcacatcc tgaatggatt gcgctttgcc ctgcatttgt
     2401 gtgagacggg actgttcaac tgccagttga tttgttgctt ctgcaagccc ttctgtgaca
     2461 gtttttaccg acgtcatgtg gttaatcata aaaccgttat cggttgtcca gcccgggttt
     2521 gccagcacat actgatagcc agcaattttt tcctgtaagg atttaatctt acttttctgc
     2581 tcgtcaatta acctgttttg ctcatcaagt gcctgccgcg tcttttcctc attatctgac
     2641 gcttcaggaa gcgacattgc cgacgttttc tggcgaattt cgtcgattgt tgcggcatac
     2701 tggcgtgcag attctctggc ctgctcctga ttctgataca tcgtgtacca ggccgtcgcc
     2761 cccagcatga cgagtcccgg cacaccacca accaacccca gcgcaccact taacagacga
     2821 ctccccactg acgtgacagt attcagcgtt gtctgtgccg ctgttctggc cgcaatatta
     2881 cgggtaagtg acgcttgggc agctgtcagc ttcgcttctg ctgcggcctg cctttcggta
     2941 ccgcgagcag caacaaccgc ctgttgcgca cgataaaccg ccgcacgcgc cctggcggtt
     3001 gctatctgtg tcccccgaag ttgcgcttca gcaagagcca cttcgtttct ggctgcagta
     3061 attaatccgg cagttgcaga tccagcagaa gacgccatat tgccaaaata tcgggctacc
     3121 ccgacggcaa ccagagcacc ggcagcggtt gccacggtgt caatattgcc tgcaagacca
     3181 ttcagcaccc cggagagcgt cttcgtcact ccgcttgcct cgttcgcacc accaacccag
     3241 gccataaagg cgttttcaac tttggttgca gaggatgaaa ccgtatcagg cattgctgca
     3301 tattcatcac gcaacgcccc aagctgacta atcagtgcag gaacaacctt atcggcggtt
     3361 agttttccgt tatccgccat ggccttcaga tccttacggg caacgcccat tcccgcagcc
     3421 agcgcacgaa taacacgatc accgctctca ttcaccgagt taaactcttc accgcgcagc
     3481 actccctgcg ccagtgcctg actgaactgc gtgatcaccg aactggcttc tgctgtactg
     3541 gcaccggata atttcaggcc cgtggagatc gcctcggtga ctttcagtac ctcctcagaa
     3601 ctgtaaccat actcccgcat ggaagctgca gaacgggcaa aaaggctggc gttatcagaa
     3661 aacgccgtcc ccgttctctg gctgatcgcc attaattcac gttgtgatac ctgaaaatca
     3721 tcactggact gtgaggcctg cttcagacgg gcatttactg aattccactc atcggcgaga
     3781 gaaataagat gaccggtagc aaaagccccg gcaaatgccc ccgccatatt cagtgccgaa
     3841 gatttagctg tatttatctg atccgtcact tctgccagtg cacgccgcat ttcacgggat
     3901 gcagcagcgg actgccggcc tccgttctgc atggtacggt agtaatcctg ccccatacgc
     3961 gaagcccggg agatctctga ctggaatgac cgggaatttg ccgagatttt aataatcagt
     4021 tcacgtaatg tcgccacact cattctccgg acgaaaaaaa accgccgaag cggttatgtt
     4081 gactcactga gacactatta aaagcgcttt ttccagtccg gcaaatggat ctgatacgcc
     4141 ttctgtctgc tccttctccc actgaagaag cgcatcattc agtgacactt tgaccccctg
     4201 cgcaccgtaa acagctgaaa caatctgggc agcccggaaa tcagcccgtt cgtcccccag
     4261 cgggctgaac ctgtcaaatt ctgcccacat catgatttct gatgcggaca tttcccggcg
     4321 taactctgac aatgtgcgcc ccatcctgag cgccagcatc atcagaaaac gcatccccgg
     4381 aagcgctact tttttttaac ctcgccggca tcactgatca gttccagaga ctgccgaaga
     4441 agccgcgcat gcaccgggcc atacacggca atcacctgtt cacgatcatc ctctgaaaat
     4501 acgggttgca gtccggtatc acacagaaca tcaatgaaca gttcaacatc tgcctccaga
     4561 tttcggcggg cgcgctccgc aacggataac ggtgtctcat tatcttttgc tttaacgatc
     4621 tcctgccagc gcaaccaggc ttctgcagaa ggttcccgta atacaaccgt tgccccttcc
     4681 cattcaggca catcaacagt tttatggcga aaccccgaca tcgttgccag tgccagattg
     4741 cggatatttt tagtcatcac atctatcctc attaactgac ggtaacagtg caggaagtgg
     4801 aggtcacctt gttaacaggg cttgctgaat cagaaatctc gcaggtatac gcacccgcat
     4861 caccggatga tgctgatgcc ttactgaacg ttgccgccgt ctgtccggaa acaggagaac
     4921 cacctttctt ccagacataa gaataaggcg gcacaccacc cgcagcctca accgccattt
     4981 caagtttcgc tccggaagca acccgcagcg tgctttttaa atcaaccttc actttcagcg
     5041 aagctgtcgt cagcacaggt ttgcctttca gacgcaggga aaacgttgca gccacaacac
     5101 cattggttcc tgcagaccag gtatgctgac gcacttctgc cataaaggta aatccgttgc
     5161 ctgacggaaa aataacttta aagccatacg tggtgtcatt gtcataggca ctgcgcaacg
     5221 cgttctgggc agcattgagg taaaagttgc ctgacatgga aatctctgac gcggcaccaa
     5281 gaccgttaat attttcctgc tcaacagaac acagcgtggt gacatcaata tcctgctttt
     5341 gtccagcggt aaactgcact tctttgattg tacagctcag gccaagatag ctggcagaat
     5401 ccagggtttc tgctgttacc ggtgcagacg aaatcataat tttcgtcagt tgcgaacgct
     5461 caaaattaga ggacatactc gtctcctgaa aataaaaaac ccgccagcgg cgggtgggta
     5521 aaatcattaa cgacctcagg ctattacctg aaattcaagc gtggctctgc tcagacggga
     5581 atcaggatca taaccctgcg ttttagaaat aacggagggt gccagtttcc ttaccgcatc
     5641 aagcgcctgc tcacgaatat tatctgcgtc atcaggtact gtcgcccaga catcgatctg
     5701 cacggtaatt ctggattcag cctgcccatc aagcacatca gatgccgtgt cagacaccac
     5761 agaaaacacc agccacggcg gagataccgc aggctttccc tccgtcagcg ggaccacata
     5821 aggataaacc tgtcctccgg ccagctgaga caacagggaa tacagtgtgg cctccctcat
     5881 ttacttaaga cctcatcaat agcctgattc attcgctgta tggcaacctg cgccgccagc
     5941 tcctctgtcg tatcgaaagc cgggcgaatg aatggatgcg cgggcatgtt tatcgttccc
     6001 agctccacaa agcgccagta aaatgcattt cggggatcgc tggctttcat gctgttatca
     6061 ctgtttccgg ttcgcaggtt ccgtccgcga atgtggacac ccgagataat ttccccccga
     6121 cgctttgaac gctgagtgag aacaaccaca tttttcttca gtttcccggt tcgctccggc
     6181 gcacgttcaa caactgcatc ccgcataact tcagcaccgg cacgggtggc atcgcgcaga
     6241 accttattgt tttctgccct gctgagcgtc tccaaatccc gtgcaatatc cgccaggccg
     6301 gaaaaatcaa gactgaaatc catcacacat tccccttcag gctgcagagt atttcaagcc
     6361 gggtagcgcg tgcatccggt attggtggac cttctatacc cagaatggcc cctttaaatg
     6421 caccggtcag cactttcaga cgtgaagtcg ctgtcacatc gcgccggaat ctcatccaga
     6481 ctctgaccgt agcctgagcg gtttctgctc cgcctgagat tatctccctc ccgctgatac
     6541 ccttaacttc tgcccatacg gtagctccct ccgtcaccgt ctccaccgga tgccctgacg
     6601 gagagcgggc ggtggtgaca ttcagaataa ttacgcgatc acgtaatctg cccgcctgca
     6661 tgtctcctcc tacaaaggaa taaaacgata aggctccagc agagaagaaa aaccaaacgg
     6721 gactggtgcc ttgctgacat ctgaggaatt ttcccggttt tcgtgccagt gcccgaccag
     6781 caacatgagc gccagcaaaa catcatcagc tataagcacc ccttcaggat caccttccgg
     6841 caccgtctcc tcataaagct tacggttgat aaaattttct gccttgcggc aggcagcccg
     6901 gaaatacagc atcagtaact catcatcagt tgcatcatct gtatcaatac ggcactgcgc
     6961 cctgagtttt tccactattg ctgccatcag aaactcctgc ccgcaacact gtgcgggcat
     7021 aaaaaaaccg cgtcggcgcg gtctgtaact gaacaacgag tggttatttg ccagtgagcg
     7081 ccttgatggc tgccacatct tccagcacac agtcaaaacg atggaaagcc agaaatgcca
     7141 cctgatcaaa ctcagcataa cgctcaacca gacgtttcag ttccatataa gtaacgcggc
     7201 gaatgataaa gcggttgaaa tcccccagga aaatgaattt ttttccggta ccaatcccgt
     7261 caatagcctg atcaataaca taagggatcc ccagcacagt agccggcgta ccgcctgcaa
     7321 tatccggcag ccataacggg cgtttctgtc catcctccat ctcttcaata gtctgcaatg
     7381 tggcatcatt gaatgcccag cggtatttcg gcccaccacg atatgccgga tcaatggcat
     7441 gtttcagggc attcatttct ttccaggtga aagcggcaga ggctgcagtc tggatggttc
     7501 ccgtcaccga cgctgccagc ccttttggct gtaacggtga tcccgttccg gtcccctgaa
     7561 ccagatattt tgcctctcca cgaccaatac gctgggcaat acggtttgcc agataagatt
     7621 caatatccac cccactgtcc tggagcagct cattggacac acgaattatt tttgatgaca
     7681 gctttttagc ccccagaata gcggtcccga acgtcacatc ctgttccgtt gcggctgtat
     7741 tctccgccag cagttcgccc tcttcagtcg tgccatcaga cgttgaccag gtgatatcct
     7801 gcccggttga tgtggtcaga agttgcgcca cactggcaat cccgccataa gccttcatgg
     7861 tgtcaatgat tttgttacgc atctgcgtgg gcaccgtata tccgccctga gaatccgttg
     7921 ttacactctg agcccgcagt tcacgcatca gattacgctc ttcagcattc agttctgcaa
     7981 atccggcacg cagaaaacgg ttaaatgccg cagcgcgctt ctcttccacc gcctttttcc
     8041 cgttctccgc ctcattattc tggcgctctt ccggcccgga ctcatccaca tatgcctgat
     8101 cctgacggcg caactcttct tcacgggcga tttgctcatc cagcgcatcc agctcagctt
     8161 tcgccctgtt ccactctgcc cgttgctcat cagtccatgc gttatcacca attttttcat
     8221 gcagtgcacg catatccttt gcaatggtgt ttcgtttttg cttcatctca tgaagtttca
     8281 tcgtcagtag tatccttatg cattaagaag ggtcaaaaga cgctcacgcg ccattcgttc
     8341 gttaacagct ttcttcagcg caccactcgc ccgcgcttcc tgccaggctt tcattgagcg
     8401 gacaccagag tctgcgtcct gataggccgg atatgtcacc gggctgacgt catacagacg
     8461 agaaatgcgc gtgatttccc ggataacaat cccctcgtcg tcttcatacc agctctctcc
     8521 gtcacgggcg acacgaaacg cgaacgagga ctgattaatg tcaccacgca acattggaga
     8581 cagcaccagg tcacaaatag tcggagtatc cggtgcaaca atgtcataac gtaaaccgcg
     8641 ttcatccacc gacaatgaca acgtgccggc agaacttcgt ccgagaatga aattaggatc
     8701 atgattaaac aagccacgta catcatcatt cagtacatca tcaaaagccc ccggcttgat
     8761 gatttcacga aatccccaca gaggttctga acgactgtta aataccgagc cataccccag
     8821 aatgtgggtc ggggcattat catattgttc cgcccgcacc tccccgctgt aacagcgcgt
     8881 ttcacggtca ttcatcgttc ttttcctctt tgcctttcgt atctttaaag ttattcaacg
     8941 gatttgctgc atttacgctg accagcattt catccagacc gtcaaccggg ttcatatcct
     9001 caaatgccct ggcttcattc cgactcatcc agccatctgt aatggcaaag tgatagaact
     9061 gcgcacgctc ctgtggggtc ccacggagca accccgtgag gttgaaacga acgtaatacc
     9121 cggcagcccg ttctgtacgg gtaaacaggc gacggttaag ctcctgctcc cagttcgcaa
     9181 cccagggcat catcgtgtag cgaacaaact gaatcgcctg ctgcgtaata ttcgaaaatg
     9241 tggctttttc caggtcatta atcatgtgcg ccgggacatt aaaaatcccg gcaatcatcg
     9301 accggttcag cttggtcata tcaatgatct gagcatccac cggagaaact gtcagagcgc
     9361 ggtaatccag ttgcgcaggc agcaacatgg ttttattttc ctggctgcga agcgctgtca
     9421 ccgcccgctg ccacatattt ttaagcctgc cccagctttg ttcgttcagt tcatttttca
     9481 cagaaataat accggcagga cgggcattac cgttaaaaaa ggcgctggta tactgctggc
     9541 cactcattcc cataccaatg gtttcagcat gctgcatgat cgggctcagt cccattttct
     9601 gattgtttcc cagcgccctg atatggatca tgtcgtccgg acttaccgca aatgcaccct
     9661 cttcgttata caccccgtaa gtatgacgcc caccggtgtt aagtaacgtg gtttcccatg
     9721 gcatacagca ttcaaggctg gtaacctctc cacgacgatt acgttttacc cacgtataac
     9781 cattgcccca ccccagcaca tgacgctgct tcagttcccg ccacttatag ctggtctgcc
     9841 aggcattcgg ttcatcatga acgagccaga acaacggatg atcgcgtgca ggctgaacat
     9901 gctcattcgt ttttcgcatc acatgcaggg gcatctgagc cacactggat gaaataacat
     9961 aaatacaggc atagacagca gccagcttca tggatgtttc cggactgaca tacacatccc
    10021 gggcaaaaat attatccgtc tcagcggcct ctccggttac cggaaccgag ggattttcca
    10081 gaggctcact gcgaaacaga gcatcaagaa gcatgttttc tcctcatgga caccaccagt
    10141 gcataaagca gcaacaaaca gcccgacagc atcagagacg ctggcagacc tgcatacaga
    10201 taaacgccag cagtgagcaa accgaaaccg atcagcccgg tcatatcagt aataagctgt
    10261 ttcacagaat taacaggtcc tcatcaggat caagcgtgga cagaaagtca ttcacgcccc
    10321 cgccatttac cagaaagcgg ctcatggccg taaaaagcgc aacagggccg tcgattttgg
    10381 cttcaggcgt ggatttattc gggaagatgt tgtcgttttt gtccggtttt accgtaacgt
    10441 tagacatcat ccagttcatg accggatgat tgctgtgatg gaaacgcccg gcataaacca
    10501 gtgattccgt ttccttcatg gcctctgaca gattgcggac cgtctgcgga acctccacca
    10561 gcggtatccc ttcttcagcc agtgccaggc tgaactgcat tgcgctccac gggtcaaatc
    10621 ccagttccct gaggttttca ccgccaatcc attccagtaa gtcacttttt atctgagcat
    10681 gatcgataac atcaccatcc gtcaggatga gcttatccat ctccgcccac ttccggtaaa
    10741 gttctgcctg ctgccgcgag catcgctcca gccgtccttc cggaagccag aatttaaaat
    10801 cagcatgaac atgtccgtta tcggttcgcc atagttttgc cgccgcacag atatcaatct
    10861 tatgagcaag gtctacgccg acccacatgg gatatgtttt cagctcatgt tgtggagcaa
    10921 tgtattcgca cttctcccac ttaatcatat ccatccaggc agattcggca gtgacccaca
    10981 cattcatgtg tttggtaaaa aaattcaccc gcgcagagac ctgctccttc gcttttttcg
    11041 ccagacgacg cagatcatcc cagcgtttac agatgcccag gccaggattc gctttctgcc
    11101 agaccgtttc atcaaacgga tcatctccct catcgagcgt gtaaatgatc gcaaagtagg
    11161 agtcgtcttt taccgcgccc tccacgtcgc tgttatagcc tcgcaatacc ttgatggcgt
    11221 aatcacgctg ctcgtagcaa atcccttcct tgttaaagcc agccgtggtg atgccaaata
    11281 acagagactg cagacgggca ccggttgccg tttccagaac gtcccacacg tcacgggttt
    11341 tatgagcatg cagttcatca ataatggcgc agtggatgtt cagaccgtcc aggttgtttg
    11401 catccgagga aagcggttca aattttgatg cgctctgctc ctggtaaatc gccagcttgt
    11461 tgaagtcaaa caaccgcccg agtgtcgacc gggcttttct gaccatattt ttggcgtctt
    11521 caaacacgat tctggcctga tcacgcgtgg ttgcggctga atacacctca gccccgcctt
    11581 caccatctgc ccccgtcata tacagaccga tacccgatga cagggttgat tttgcgtttt
    11641 tacgggcaac ttcgttgtat gctgtccgga accggcgcac catcaccggg cgtccactgc
    11701 catcgctgcg catgacaact tccccggttt cttcattcac cagcggaatg acaaaaccaa
    11761 aaatattaat gaggataaac acatgccagt ccatcaactc aatgggctga cctgccagcg
    11821 cccctttcac atggggtaca aatttgtaga aattaaggat gtgctgtgca cgaggttcac
    11881 tgaaataaat cccccgctct tcgccgtact tcagatcatc aagaaaacgc tggcaggcca
    11941 gacggacaaa ttcgccagca acaatttctc ctgcaacaac acgttcggcg tagcggatcc
    12001 cgtcagccac ttttgccatc agtctctcgc ttttaaaagc tctgccagcg gatcaacatc
    12061 atccggtccg gcggtattta ctttcgcccg gcttgccggt gacataccaa actctgcaag
    12121 catcgcccga atccgcttcc aggcatcagc cttcatcgca gcagccgggt gtgccttgat
    12181 cagcacatcg ccattctgcg tttccgtgcg gtaggtataa ccctcaacat cgagtatttc
    12241 gcagtgatgc cggtattcgg tgtaggcttc caccagtaac tcgagcgcac gtgcatcgag
    12301 ctgagaaatg atcccttccg cattcagctc ttccgccatt cgcctgaacc agtacttccc
    12361 ctgcgcccct aaatgttgcg gaattttagg gagacctttt tcatcctttt tagcggtttt
    12421 tttggagtct ttaactggcc gctttgaggg gttacctcgt atcaaatgca ggcgtggcgg
    12481 ggttttcggg ggtccagaca taatcgattt tacctatcaa tcatttaatc acattccaaa
    12541 aaaaagtttt cgaacctgcg gcgatgcgag gaaaggtcag gcggcggtac tgagcagcca
    12601 gggttgcaga gatttgaccc gcccctcccc tacagatggg aactgttatc aattgatgcg
    12661 ttcgcgcgct gtttttgctt tatgacaggg ccagcacaga ctctgcaggt tactgtctgc
    12721 atccgtgcca ccatgagctt tcggaatgat gtggtccaca gttctggctt caacggctct
    12781 cccattgcgc aggcagttct gacacagatg attatcacgc ttcagtatgc gcgcacgtat
    12841 ggcatcccat ttcgagccat agccacgctg gtggcggctc agtccgcgtt gatgctgtac
    12901 ccatccttcg ccacgatgtt tatcgcagta accagaactg tctgtggttg tacctgcaca
    12961 tccacgctta cggcaggcgc gtgggattcg tgatggcata aatacctcac cccctgttca
    13021 gttgaatgac gggctgattc tcgatatgtt ctgctgtcag tctgaaagtc acagtgactg
    13081 ttggtggctc gcctccgcgt gactctgtcc tggcggaaag ctgcccttcc agtaactcac
    13141 catcaactgc aatcccatac cctgcgaaat gtttaccacg atacagttta gcgacctgaa
    13201 acttcataac tcttcctttt agacatgtta gacgtgaacc tgtcgcacgg cagagtcgcc
    13261 gaaagtttac ggtttaccca ggctcacagc tgaaagcctt tcttagatgt gcacatgcga
    13321 tatgctttga atgaattatt aaaaacttta ctctttttca aaatttcgaa tcctggctcg
    13381 ttaatgttaa agaattaaac gtaagaaagt agtatgttga atcgcttata tcaaaataca
    13441 taggactcaa aatgccagaa ctcgttgatc caacagactc attaattagt tttcaatacg
    13501 ccttttctaa tggtctgatt aagccttcac catgcatagt tcacccaaat atgaaggtgc
    13561 ttttggatga tgcagagggt acaccacggt ttacttatgc attctttgaa ggagaaaatg
    13621 ttaaaggtgt tgctatatat gtccctgcag agtttgttga aggtaaacca tgctttggcg
    13681 ttggctatgc agtagccgat gaatataaag cgcaaggcat cggtactcaa cttctcatcg
    13741 ccagcattga agaaatgcaa tacggattta gaaattcctt caatgaattc tatgtagagg
    13801 ctattgtcgg ggttggtaat caagcctcca acaaattagc tgcaaaagtt ttatctgata
    13861 ctcctgagcc agggacagat tcttactcag gaaaacctat caatcagtac atgaaacttt
    13921 tcaaaaccac aaaataacta ccattctggc gcagattttt gcgccttttc aggtttgcag
    13981 ttcacctgcc acgctttgtt atgcacctga atgtcccgct tcgtctgttg cattatcata
    14041 agtaatagcg taggttgaca ccttggctct ctttcgccac cggcgaatct ttagcggatt
    14101 atccttggcc gttttttatc tgagacattg ctcacgaatg tatagctgtg ccccttccag
    14161 ttgcttctgc atcgtcatca accgttctct gagggtgaaa taatcccgtt cagcggtgtc
    14221 tgccagtcgg gggctggttg cattatccac gctggtgggt ccggtggctt cacgcacggc
    14281 tgcggagcaa ctggcattga cccgcaggcg cttacgacca gcggcaacat cagcgcgcag
    14341 agtttcattt tcagctttcg cattggctaa ttctctcgag tactttgcat cgagcgcagc
    14401 aacatcacgc tgacgctgtt gcatgtcagc gatggtggca gtcgcctgct tcagctcact
    14461 gactttttta tcacgctgtt ctttgtaggc gatggcgtta tcacggtaat gattgaccgc
    14521 ccacgacagg cagacgatgg tgcagataac cagagtataa ataatcgctg cgactctgct
    14581 cactgatcta tcccccaaca ggctaatgcg ctttcctggt cacgacgaat aacctgtcca
    14641 tagcagttat ttgaacgtat gcggcaatcg cgcccaccat cttttatcca ccagcgaatc
    14701 gcctcgcatg cgcccttacg atcaccggca ttcagccgct tataaaacgt cgacgggaaa
    14761 cacttaccgg ggccaatgtt atagggacag aatgacgcta tacccgcttt ctgtggttcg
    14821 gtcagtggta ctttaatatt gcgctccacc catgccaacg ccttatcacg ttcaatagcg
    14881 ttaacctggt cgcatttttc cttcgacagc ttcattcccg gtatgacggg cttaccatcc
    14941 accattgtgg caccacgaca gatggtccat ataccggaac catcgcggta tgccgtagtg
    15001 tggttaccct ctttttcatc cagaaactgg tcaagtattt gaggagcaga cgcgcctgca
    15061 gcaatcagcg ccagaacagc agctgacagg ccgtatttga tttttgcgct catggatatt
    15121 tatcaggatg ctaccaatga aagatactgg aaagccaact gcaaaaagct aacaacctgt
    15181 aatcgagtta tcagaactgt taatttttat ggtataccgc gcctctgaac aggggcgcgt
    15241 ttctggcaac agctcgtccc cttcacataa cccggcagca acatccagga agacctgtct
    15301 gatgctcctt ctggctgctg cctcataaaa ctccagcgcg gcaccttcaa cacggtccag
    15361 cgagatgtcc aagccaaaaa tttcaccgtc aaagcgtttt ttgtcccgta acgctaaagt
    15421 taccgtaact ttattctcaa aattgcggat ccctttcaca atcagttcat agttttgagt
    15481 cattgaatta ctctccccgt gcagccttac gcttgtcttc tctgattttg aagtacagat
    15541 ttgtcagata agtcaggaag cccagaacca gactccccag tacaccaatc gcagcccact
    15601 gtgacggact gacctgatca agccactgta aaaaccagta gccagcactg cctgcggagg
    15661 tgccgtaggc aatgcccgtt gaaattttgt ccatggattt catagcctca cctccgcaaa
    15721 taacggatgg cgtagtttta cactgagaaa tgaaagggat ttgaaaagaa aaaaccgcaa
    15781 aagcgggcga aacgatatat acagaaagga aagcactcta tccaacaaac cacacccaca
    15841 gttaatcgga ataaaagcag agtgcttatg aatgatcgcc tgcccgaagg ttagtatttc
    15901 tgcacagcaa ttttgcaaaa aaaggcgatc attcataact taaacgtctt tcagtcactc
    15961 cgggatttcc catcatcgca gactgaaaga ctctaactgg agcgggcagc gggaatcgaa
    16021 cccgcatcat cagcttggaa ggctgaggta atagccatta tacgatgccc gcatatggtg
    16081 ccgactaccg gaatcgaact ggtgacctac tgattacaag tcagttgctc tacctactga
    16141 gctaagtcgg cactggaccg ccaccgggga ctcgaacctc gcacactcaa cttaaagggt
    16201 tgacgctctt tcctgatgag ctagtggcgg ctggtggccc ttgctggatt tgaaccagcg
    16261 acctggcgat tatgagtcgc tcgctctcac cactgagcta aagggccggg cgcaggataa
    16321 taacgttacg aaatcaatgt tgcaagcatt caaaaatcac ccttatctcc tccaccagcg
    16381 cattcaccat gtctatccga gataagtggc acaaaaaacc cgcttgtggg cgggttttgt
    16441 ttgcttttgc catcacgtac aaaatcggca aaatatcaga tttgcatgaa atatatgcct
    16501 ttcaatctac ttttgcaaca ctttgctttg aaaatgccgc cttttgtttt gaacgtgttc
    16561 tcattacaaa caataaagcc tcactatcaa gtcggtgaaa aatgtgtttc attgcaaccc
    16621 agtgacgagt aaatgttttg gaccagtttt tagttgtcac tcccgccagt aatgccagct
    16681 cctggtattc ataaccttcc ccaccaaaaa gttctgcttt taatgcctgc gccgccagcc
    16741 agattaattt tttcaggcgt tcctgcgttt tccctgcaat ttttctggta ccggattgag
    16801 tattaaattc attccacgcc cactgtgtta tcgcgatctg atattcccaa caaatactcc
    16861 cgctgtaaca ccacaacaac caggctttat gatgttcttc aagagacaga actgcccgtc
    16921 gccatgatga tgtcgaaaac tcaacctgac ttaccagagc aattgatgag cctttcgcca
    16981 gtgattgttt tcccggtatc ggtggactat cccgcgttat cattcttcca gtcacttcat
    17041 cgcggtaccg gattttttta cgcctgtaac gccctgtatc aaacatggca ttctcctgcc
    17101 aggcttcaag ctgacctttt gttgccccac tcaaatcagc ggtagcgata atgagctgct
    17161 cacgcacaaa ctgtaaatac tggttattca tgcgcactcc agttctgtga tttttatccc
    17221 cagccgacca ccaggaacag gcagtccgcg cacaatattg atttcatcaa actgctcgtc
    17281 gtctatgaga agtccggcat gcgtcagcgc atccagtggt gccttcagga tattgtccag
    17341 gtcgcggcgg cgcttatccg gtggctctgc aataattttt attgccagcc ttccggacag
    17401 gtttaatttc aaccgctgct ggcgaacaat tagtgccaca tcacggcgat aacgctcacc
    17461 gacttttgat acaaaatatg tgttgccacg acgtcgccag taagtattca ccgtcggcgg
    17521 ataaggcaaa acaaactcta tacgcatcag taacctcttt tacccgagca cgccggttgc
    17581 aaaggcgtga tcaagaaaac gaaaaattaa atcaacctgg gaaccatgct tttcttcgaa
    17641 cgccagcgga tccgcatgaa gttcgttgtg atgttcccgg cacaacggta gcgtgaaaat
    17701 atcgtgggcc tttgttccca tccctccctg accgtgacca atcaggtgat ggggatcgtc
    17761 ggctggctga ccacaacacg cacacggctg tgtcttcacc cagcgcgtat atttctcatt
    17821 tagccaacgg cgacgtttag gtcgcctcat gaaagattcc ggagactccg gatcaacggt
    17881 gatgcatacc accgtctttt cctgtggtgg gttctgttgc tggtgggcat gaggcaacgg
    17941 cgcaagattt tttgtgcgct gcttcagtat gctggtggcg gtctgctctc ccggtacgat
    18001 gtcgctttcg cggtacaagg agcggatttt ttccgcacgt acccccagag aacgacgtaa
    18061 tactgcctcc ggaagcgcgt ccgccacctg attgcagacc gcccaccaag ataattcagc
    18121 cagcgacaat tcccgctcct gcgtgccatt cattgcatgg cgtatgacgt caatcatcca
    18181 tgctgacagg ttttgatgag caagttgccc gagtgattcg gatgtctggt cacgcaactg
    18241 gttgtcgcag tgccagcaca acaccatcgc gctggtaccg taacgatgta tgacgatttc
    18301 actgtgatga tagtcaccat gaggccactg gcaggatttg acatgacgca acagccagtc
    18361 agacagcgcc ccagcgccgc cagcagcacg aatcacccgc tcatcgctga aaaatggcag
    18421 taatgattta tcctccgcca gcggctggcg aacggcaggg acgactccgg acggcagacc
    18481 gcgcatgctt ttcggttcag gctccaccag cactcgaggg ttatgaaata cttgcatgga
    18541 ttcacggccc ggcctaagga ccaccagccc gagttccggt accagaacag gtcgaagtaa
    18601 tatccgcacg ttacctccag atccgttgct ggtatgtgcg ggatgggcgc ggtgggcgtt
    18661 cggaataagg gagcctgaca tagattatcc agtgacgata atcgaggctg agggctttct
    18721 taatctcgta tccgcgtctg cgatagttat gaattagcca ttcggcctgt tcttcagtac
    18781 atgggtcatg ctggaaccag tcagatttga aagtgcggga acgccgcccg tgcctgctgg
    18841 caaagacggc agaatcatca gaattgtgta atttggtatc gtgcgccatc ggttgtctct
    18901 gctggcgcag caggtgccag ttgttcaggc tggcgtgcga attgtaaacc agaatgccag
    18961 gaaaaaacaa aacccgccga agcgggtatg ctaaaacaaa ctgaaagtaa tataccggac
    19021 ttgtaaagga acgatagaat aattattgga ttaaaccctg actcaatcca gatttcatag
    19081 acaacaacta cggactaatc atcacagtca tgtttgatag acttagtcca cattgggtga
    19141 gggtttacgg cgttttcact aataatttat cgtccaagct atacactact gccctgtttt
    19201 aacgaagttt ttaaaggaaa caactgcctg ataggggttt ggttgacagc caaacatatt
    19261 atcgcaaaaa ggcttgatga aaattcttga ggatccatct tcatttggca ttttactcac
    19321 ttgataagcg aggaatggac tatttggaga gggattataa gtggaaatta gcgtgtctgt
    19381 cgccgtttga attttccatg aggaattatt agccaaccag aattgcgctc gtttccaata
    19441 aaagtcacat tgcttttcat cattacatgt tagtggcttc attgcttctg ctttcaacgc
    19501 tggatcgatc tttgctgcac accctcccaa cattactgtt gcaatcatta cacctgcgac
    19561 taaaacaagt ttcttcatct ccctgcccca tcaataaaag ttcggttctc taataactag
    19621 agttaatcaa cggaaaaaac gccgaagcgg gttaagtgcg ggtgcgttga ggatgcctga
    19681 cacatcagag gtggcgaggg atttctcccc cgccaggtct cttactcctc aggttcgtaa
    19741 gctgtgaaga cagcgacctc cgtctggccg gttcggattc gtacctcgca gaggtctttc
    19801 ctcgttacca gtgccgtcac aatgacggtt aaacagatga cgatcagggc gattaacatc
    19861 gccttttgct gcttcatagc ctgcttctcc ttgcctttcg gcacgtaaga ggctaaccta
    19921 gatttgccgt tcatagattg agcctcagat taatgttaag cgtcttgcag gacgcgtaat
    19981 gttaactggg gcttttctct atctgccttt ggtgttcatg cctgagacag atagcctcaa
    20041 gcacccgcag ccattctact taactcccgt tacctcgcca atataaaatc aatcagaaag
    20101 gtgatccata aaatcactcc ttctcttctt ttccgtagtg gagttggcca attttgataa
    20161 gagggcgtcc ctgagatttg cggtgtagat tggtatcgcg cagagaatac acacagccac
    20221 aatattcctg ctgatagaat ttttcgcgct tgctgatttc aatcatacgg gacgagccgc
    20281 cctgcttgcg ccagttataa tcccagtaca ccatacccgg ataatgcgca acagctcgcc
    20341 gcccacactc gttaacctgc tgcatatttt tccagcgtga aatgcccagt gaactgctga
    20401 tcacactgaa accattttca gcagcgtaca acgctgtccg ctcaaaacgc atgtcaaaac
    20461 acatggtaca acggatcccc ctctcaggct cccattccat tcctttggca cgttcaaacc
    20521 agttgtcggt gtcgtaatca gcatcgataa acggcacgcc gtgttgttca gcaaagcgaa
    20581 tattttcatc cttacgaatt aaatactctt tctgaggatg aatgttcggg ttgtagaaaa
    20641 agatggtgta gtcgattccc gaggcctgaa gcgcctccat cacttcaccg gaacatggag
    20701 cacagcaaga gtgcagtagt agtttgtttg ccccgtttgg gagctccaat ttaggccgtt
    20761 tgaaatcagc aatagtcata aatattttta ttggggtcat gaaaatagca cagagtgtag
    20821 catcagagca ggtctatcgg gaatatatgt ctaaatctgg taatatctgg ttttgacgca
    20881 aagcggacaa ccacgctggc tctaccctgc gccatgaaaa tgtcaattca catctgaact
    20941 aatgctcttt aatctagtaa cgtctaaaat acctaacatt tccttgataa aatgccagta
    21001 cacgctgcat agcttcgctc ttccggcact cgcgacagat tatattcagg cgcctgtcgt
    21061 agcggcgtat ttcgccgtct ggtaacgacc agataaggtc cggatcaacc actgcaggtt
    21121 tcttcacctt tgcccttgag agttttttgc gagcattttg ccagtcctta cgcgcctgtt
    21181 cagacgggaa taacccgtaa ccagagttgt atacatcgcc actggcaacc agctctctgg
    21241 cgagaacact catcagatat cttgtcgcac ctgtcctggc ttccagttgc cgcaacgtct
    21301 cgcgaccgct cagacgtaca agttcaacaa cctgcccttt aattttttcc cgctcttctt
    21361 gtgtaaatac ttttgccata agcgcctccg gcaatcactt ttccgataca acacggcggg
    21421 aagaatcagt aatctgtcga acaatatccc ggtgcttgtt cagctcccgc agcgcggcgc
    21481 agactcgctc ccacttctga acatcacttt tcgccctgcg cagcgccagg tttgccctgc
    21541 gaagggacgg aaaaatcagc tcatctgctt gcgtttcggt aaacgatggc aacggctgca
    21601 caatgtccgc cacagtttct gttttaattt cttcctgtgt tgcggcttcc cggactggta
    21661 acgcagcacc tgctggctga ggaaaggcct taccatcact ttccgttacc agcgcggctt
    21721 tcggctctgc tggtaaatta tcgcccggca tgcagtaacg aaatttaccg ttctgattaa
    21781 cgcgtgccag ccgccccgtt gcggttacca ccgccagcgt ggaagcaacc ttgcgagtac
    21841 tgacaccgaa cttacccgcc agttcctcac acgttttagc cccatcctga ccgataaact
    21901 caatcatcat gtctgcggta actttttgtt cgacctcccc ggtcagcata tcctgtgctt
    21961 cagattttac tggccgctct tcggttaccc gggattcacc ttcgccagcc agaaaccagg
    22021 tgtgaccagt tttatcaacg acgccttttc ttttgagttc ccacagctcg ttgacagcct
    22081 cttcacgact gattccaagg cgagctgcca ccacatgtga agaggctttt ttcagtgctt
    22141 tcagtgcgtc agatacggtt tccattaaaa tttcctccgg acaaaattac ttcacaaccc
    22201 tcatattgct gacatttgga cgccagctat cccagttaaa cgtcacccat cgaccaccgt
    22261 tcatggtcat gcggtccata atcctctcac caagaagcgt actcattgcg gcatgattca
    22321 ggtttgttaa catcccgaca ctgcacagtg atgctgtccg gcgatcaatt atctggtgca
    22381 ataccacctg ctcgtttttc gtctcccgct gaacgcctat ttcatccagg accagcaaat
    22441 caaccccgca aagctcctgt aaaaattttt ccccggattt gccgttgtcg tagctgtcat
    22501 gcaacacgct catgacgtca gacacggtga cgataatcac gctgcgcccc ttcaccatca
    22561 gccggttgcc catcgccgct gcaaggtgat ttttcccggt gccggtttta ccgctgaaca
    22621 caaaattcgt gcacccggtc atcagttcgt cagctatgga tttggcctgg ctcagcgcgt
    22681 atttttgccc gtcgttctgc acctgataat ttgcaaacga gcatttgctg tgcagaggct
    22741 ggatgcccga acgattcagg attttttcca cccgcaactg gcgattctgg cggttaatct
    22801 cctcgctgcg ttttcgtcct tcagcaagtt gccattcccg ccactcctcc accgtccggt
    22861 acggtggaac cgacccctgt ggtgcaagtc tgcgaatacg ttcaagaacc ccaactgccg
    22921 caatgttttt catgacacgt caccccctga atcccggcgg tatttcagtg tccggttcag
    22981 aaatgtgatt cacgcaacgc tgcgcaggcg aacgccccag gcggataacc agttcatccc
    23041 atttttcccg gagttttgcc ggactcatga tgttttttac ccagaacgaa tcccgctgga
    23101 gacgcccaaa catttcacaa atttgtctgt gagttctgcc atccagcatc cgcattgtgc
    23161 gaacgtcatt ggcccatgct gtccagttgg gttctttcgg tctagtgatc tcgccatcat
    23221 agctggccgc ctgctcgtaa agactcacga ttcgtcccca gatccactgt gcgcacacca
    23281 aatcttcctg acttccccac tggcgttttt tcgcactgaa cacaaccgcg tcagggtgtc
    23341 gggttaaaaa atcctgttca gccgtctgcg ggtccggttg cgaagcgtcc ggacaagaag
    23401 atcttttatc tgacggatca ggttttaata ctgacggatc ggggtcaatc atcgcccccc
    23461 taatcggcag ttttttatca acagttgatc catcaaaatt tgacgggtca accgttgagg
    23521 ggtcaatatt tgacgggtca actgttaacg ggtcattttt tgccgggcta atttttcttt
    23581 tcggtttata tgactcacgc gccgccgccg cagctgcttc gagtttttcc acattaagcc
    23641 gatagatatt gcttacatta cgcccaccga ccttacgctc ttccttcgtc agccagccct
    23701 ctttcgccag ttctgcaata gccgatttca ctgtggattc acttcttgca ccgatctgac
    23761 gccggatagt ttcaatggca ggccatgaca cgccctcgtc attgctgtag tctgcaagac
    23821 gggccataac cgccaccctg gataagatca tgccggtgaa ggcgcaccct tcccagacaa
    23881 gaccatgaag cttgctgctc ataaaacccc cgaacaccgt gcttttagtg catcaccaca
    23941 gcattccctg ccgggccgcc gcgattcatc tggtcataca aaacaaccgc tgacgcaaca
    24001 aaatcatcga catccttcac cagccgatcc ctccgttcga cgatctcacg gtaatattca
    24061 gaactgtggc tgcgcatacg ggccaccagc aaaggcggca tcgccttttc gatcgccggt
    24121 aacagagcct gcattttttc aacagcatca ggggtgtctt tctctaccca gcggaaaatt
    24181 ttctgggtat tgcgagccag ggcttccgga tggctgtcgt catacagttc tgggaacgtc
    24241 atacccaact caaaataagc ctgggttatt ccagctgctg gaactttttc gccatcagga
    24301 cgcgcccagg cattcatcgc catgcggatg tgttcatgct tgattttcat gaatcaagct
    24361 cctagaaagt ggttgtgtta acgttttggt atcttccagc tcgggccaaa tattcatcca
    24421 atcaaaaggc cttagttgct gacgtgtaac ttcaccatta ctggctcgct caataaggac
    24481 acataacgat gcccctaaca cttgaccttt actcaatgcc tttcttagat aaccgatgct
    24541 ggtaccacac tcgcatgcaa acatacgctg ttcatctgac gaaagagaat tgagaaatat
    24601 tcttaattct tccatagcta ctccttagta aacacagcaa agaataccca caggtaaaca
    24661 aaagtcaata cccacaggtt gtttaccttg cggtaatcgc atctattatt tacctatgga
    24721 caaatatgaa tttagacgac agcaactcat caaaattcgt gatgagaaat gcgatggtaa
    24781 agcggttaac gtggccagaa agatcgggcg cgagccttct tatgtatcaa gaatgttgta
    24841 cccagagggg aaaaagggaa aaaaacggat cgctgatgat atggtggaga ttatcgaaga
    24901 gtcctttggg ttaccccggg gatggatgga tggtatcgtt tcatcatcaa cgaacacagc
    24961 ctccagttat gaaacaaggg ttctaacgcc acgacaacgt atttttttag atctcttaga
    25021 cgaactgcca gaaagtgaag cggataaatt attaaaaact cttgaagaga aaaaacagta
    25081 ttacaatatg atctacgaag aaatccgtaa aaagaaagca caaaacgcat catagctcac
    25141 caaacaacta gtcaccagtt aagacaccgc aaaaatttac ccatgggtat ttacttttta
    25201 aatacctatg ggtatccttc ttttcatacc aacccacccc gccccacaga atgcagggca
    25261 atacttcgag ttaccaggca gtggtcaggg gttaagtagc cagcccgagg cgtaagaaca
    25321 tgacggcagg gttcaacttt aataactatg cagcaggttt ttgttccgct accccggcgt
    25381 taaggggaaa cagaggattt ctcagtgggc gaagtcaaac atcagaatgg aaggcatcac
    25441 gggatcggca aagaagcagc aatggcgctt tatattgaca tcagcgccat tgccggacag
    25501 gtaagagtta tcagagcggt aactaagcgg tatgcgtctt tatttcagaa agtctctggt
    25561 gagtgcaccg aagatattgt caacgatttc gtcatcgaac tgcgaggact catcttcagt
    25621 tacaaggtga ccacaatttt tgcagatggc tcccgcgaaa ctgtcagagc cctgcggctt
    25681 aaaggatgtg tcaaagactt cgccaccaca ttctgggcaa gaaaacttga ttgtattcat
    25741 aaccaatttc ctctcgagta acagacccct cagaggatac cacctcgcct gacgtggtta
    25801 aaagcaggca atgcgaacca caaggagctg acatgcagaa acgagaacct gtcatcatcg
    25861 cgccagacta taccgatgat gaactttatg agtggatgcg ccagaaaatt aatgcagcgc
    25921 aggatttgaa atgggccaat gaagccaggg ctaagcaggc tgaaaatctg tccgctctgg
    25981 agcaggatat caccaggctg gaaaaagcag cggcattaag cattgccaga atgattacat
    26041 acccgcgtta atagctaacc aacgaggcta ataatggaat ttaaagattt accaatgcaa
    26101 ttccaggaaa tggcagcgaa tatagttcgt tcccaactgg cgactcttga cctgagtacc
    26161 gtagaaaaag aaaccatcga tactatatcc ggtaacgtgc gtcgtgcctt tatcggtctg
    26221 tacgaagaga agcagctctc tgataaccag gatttacatg aaaaatactt cctggatcta
    26281 atggacatca ttaataaggg gtttggcttg ttaatggaaa agaaagggat tcggatagaa
    26341 ccccttgaaa attgcttcgt aacaagaagc atcaattctt ttgattcaaa acaagagaat
    26401 taattacaga tttaacatgc tctttctcat gattgaagct ctcagggttg aaagtgcccg
    26461 gctgaagcga gtcgatataa tcaacgagat tctttcgtac cgtttcatct ttattcatgg
    26521 cagatgcaag gtatgaaatt gctaacaatg ttatatcact acgcgccgca gcatgctgta
    26581 gtgttttatc aaaatcatta attttccgta taagagagtt aagagtttca ttgacatcaa
    26641 accccatttc atcctcctga gggttagtaa ttaaggagtt ctccacgggt gaggtggagt
    26701 gcgtgcgccg gacacgggtg agcatccggc actgacagtt tactgaaagg atatctccct
    26761 gaaaagtcag ggcataacgc gaaagcgcac ggcgaagttg ttggttcata gatagcctgt
    26821 cgttaaattt tcgtcgaccg tgcgcttccg gttgtggcac tccgcgaaat ggcgcggcgg
    26881 taagtatggc ggggttattc cttccccgtt gaggacaccg ggttgtcagg ttgaccatac
    26941 gcttaagtga caaccccgct gcaacgccct ctgttatcaa ttttctggtg acgtttggcg
    27001 gtatcagttt tactccgtga ctgctctgcc gcccttttta aagtgaattt tgtgatgtgg
    27061 tgaatgcggc tgagcgcacg cggaacagtt aaaaccaaaa acagtgttat gggtggattc
    27121 tctgtatccg gcgttaattg ttaactggtt aacgtcacct ggaggcacca ggcaccgcat
    27181 caacaaagtt catttgtaaa aatggagata attatgattg ctcatcactt cggaactgat
    27241 gagattcctc gtcagtgcgt gactcccggt gattatgtta ttcataaagg aagaacatat
    27301 attgcttcgg taaacaacat taaaaaacaa cggctctata ttcgtgattt ttccacacaa
    27361 cactgtatta aggaaaccat gattaaagtc ttccttggtc gtgatggttt acctgtaaaa
    27421 gcagagtcat ggtgagcagc aataaaataa ctgccacaat acgacattca gcttaatgaa
    27481 tacatcagat ttgattctta tatgccagca atggcaggga tttgttcatc cttaaatctg
    27541 taatgaggtt aaaacaaaat gagtaaagtc tttatttgcg ccgccattcc ggacgaacag
    27601 gcaataaagg aagaaggtgc agttgctgta gccactgcca ttgaagccgg cgacgaacgc
    27661 cgcgcccgtg ccaaatttac ctggcaattc ctggagcaac atccggctgc tcaggactgc
    27721 gcttataaat ttcttgtctg tgaggataaa cccggcatgg cccgccctgc ccttgattcc
    27781 tgggataccg aatatatgca ggaaaaccac tgggatgagg aatccgcttc ctttattccg
    27841 gtcgaaccag aatccgatcc gatgaacgtc aattttgaca agctgtccct tgaagtacag
    27901 aacgcggtcc tagttaagtt cggtacatgt gaaaacatca ccgttgatat ggtgattagt
    27961 gcacaggaat tgttgcagga ggacatggca acattcgacg ggcatatcgt tgaggcattg
    28021 atgaaaatgc ctgaagttaa cgtcatgtat tcagagctta agctgctcgc catcgggtgg
    28081 gttaaacata aatgtaatcc aggtgccaaa tggcccgaaa ttcaggcaga gatgcgcatc
    28141 tggaaaaaac gtcgcgaaga tgaacgcaag gaaaccggaa aatacacgtc tgttgttgat
    28201 ctcgcccgcg ccagagccaa tcaacagcac actgaaaatt caacaggaaa aatcaacccg
    28261 gtcattgctg ccactcatcg cgaatacaag cagacatgga aaacactgga tgacgaactg
    28321 gcctacgctc tctggcctgg tgatgtggat gccggaaaca ttgacggcag catccatcgc
    28381 tgggcaaaaa atgaagttat cgacaacgac cgcgaagact ggaagcgtat ctcggcatca
    28441 atgcgcaaac agcctgatgc ccttcgctac gaccgccaga ctatttttgg ccttgtccgt
    28501 gaacgtccga tcgacattca caaagaccct gtggcactga acaaatacat tactgaatac
    28561 ctgactacaa agggcgtgtt tgaagatgaa ggaagaaatc agagcgcaac tgatactctc
    28621 tcggcgccag taccagaaac tgatgcagtg gaaacggcaa ttccggacaa cgaaaaaacc
    28681 gaatgcaaag tggaagtcga accatctgta gagcgtgagg ggccgttcta cttcctcttc
    28741 accgacaagg atggcgaaaa atacggtcgc gcaaacaaac tttctggtct gggtaaggca
    28801 ctggctgccg gggctactga aatcacgaaa gaagaatatt tcgcccgcaa aaacggtaca
    28861 tactcaggtt cacaacaaaa tactggtgca tctgacacga ccgcacaacc agggtcagta
    28921 aaagttaccg ctgacgaagt aaacaaaatt atgcaggcag ccaatatcag ccagcctgac
    28981 gccgatgaac tgcttgcagt atcacgtggt gaatttgttg aagggattag cgacccgaat
    29041 gatccgaaat gggttaaggg gatccagacc cgcgattctg tgaaccagaa ccagcaagaa
    29101 acggaacaga acgaccagaa agcggaacaa aacagcccaa atgcgttaca aaacgagcca
    29161 gaaacgaaac agcctgaacc agtggcgcaa caggaagtgg aaaaagtctg caccgcctgc
    29221 ggtcagaccg gcggcggcaa ctgccctgat tgtggcgcgg tgatgggcga cgcaacatac
    29281 caggaaacat tcgatgaaga gtatcaggtt gaagttcagg aagatgatcc ggaggaaatg
    29341 gaaggcgctg aacatccaca caaggagaat actggcggca atcagcatca tgccagcgat
    29401 aatgaaactg gcgagacggc agatcactca attaaggtga acggtcatca agaaatcaca
    29461 tccaccagca ggacgtgtga ccatctaatg atcgaccttg aaactatggg aaaaaatcct
    29521 gatgccccga tcatctcaat aggtgcaata tttttcgatc cgcaaaccgg agatatggga
    29581 ccggaattta gtaagactat cgatctggaa actgctggcg gagtcattga tcgggacacc
    29641 attaaatggt ggcttaagca atcacgcgaa gcgcaatctg ccattatgac cgatgaaatc
    29701 ccgttagatg atgcactgtt acaattgcgg gaatttatcg acgaaaactc cggtgaattt
    29761 tttgttcagg tctggggaaa tggagccaac ttcgacaaca cgattttgcg ccgttcatac
    29821 gaacggcagg ggatcccctg cccgtggcgt tactacaacg atcgcgatgt acgcacaatc
    29881 gttgagctgg ggaaagccat agacttcgat gccagaacgg ctattccatt cgaaggtgag
    29941 cgccataatg cacttgatga cgcccgttac caggcaaaat acgtttcagt tatctggcaa
    30001 aaactgatcc cgagtcaggc tgatttttaa tgttcaaccg tcgccagttg tcgttgatat
    30061 tctgcaactg gcgcgttccg gagtgatagc catgagcgaa cagtacctga taacgctcga
    30121 cgagtggaaa ccaaaacggt tcagtctccc aataacaaac actaccctgg tgaaatacgg
    30181 aaaactagga tacatcgttc caaggccaca aaaaattcgt gggcgttggc tgatagatcg
    30241 ccgagcagtg tttgttgggc ctggtgaaac gggaattgcg ccggaaattc atactggcga
    30301 tgatgatgca ctgaaggaga ttttaactca tgtcaccgag gccacgaaaa aacagcactg
    30361 acgtagccgg tctttacgaa aagtttgatc gcagaactgg cagagtttac taccagtata
    30421 aaaatcctgt gactggaaaa tttcacggac tcggaacaga caaatgtaag gcagaaaaaa
    30481 tcgcttccac agccaatcag cgaatagctg cagcagaagc tgaatatttc atgcgcaaaa
    30541 ttgatgaaag tccgtcagca acaaaacgtc ggggtatcag attaaaggca tgggttgatc
    30601 gatatctgaa aatacaggac acgcgactga aaaatggaga tattgcagct acaactcaca
    30661 aagaaaaaac ccgaatggct gcatacctgg tttcccgtct gggaaaccac ccattgaaag
    30721 aactggaagt aagagacttt gcattaatac tggatgagtg gctggataaa gacatggtca
    30781 gcacagcgag agtaaatcgt ggattatggg ttgatattta taaagaagca cagcatgcag
    30841 gggaagttcc tcctggatgg aatcctccgg aggctacccg taaaccgatc cctaaagtaa
    30901 ccagagccag gctcaccatg gaagactggc aaaaaattta caatgcaacg cctgaaaaac
    30961 actttatccg taacgcaatg cttcttgcga ttgttactgg tcagcgccgt gatgacattt
    31021 gccacatgcg tttttcagat gtgtggaacg aacacttgca tatcacccag ggaaaaaccg
    31081 gaatgcgtct ggcgttaccg cttacactac gctgtgatgc cattgggata acgttaaaag
    31141 aagttattga tgggtgccga gacagaatat taagtccata tctaatccat agtcggcacc
    31201 agaaacaacc gaagccgatg agtaaagaca acctgagcga ctactttgcc aaagcacggg
    31261 atctggctgg gataattcca ccagcaggaa aaactccgcc aacatttcat gaacaacgct
    31321 ctctatcaga acggctgtac cgtgcacagg gtatcgatac aaaaacatta ctaggacata
    31381 aagtccaggc aaccaccgat cgctataacg atactcgagg tcaggaatgg gttaagttgg
    31441 ttatttgaca aacaccatat ggaatatccg tcaccatctc aggaaaaaag tgttgtaaaa
    31501 tgcgtggcct agttttgggg aaacgttttg gagagatttt ggagaaagga aaaaattgaa
    31561 taaattcaaa atcctgaaag tgtcccgcct tatgaataaa aaggtggaac tcgaatgatc
    31621 ggtcgactgc ttcgcggcgg ttttatgacc gctatctacg cgtacctgta tatcccaatc
    31681 attattttga ttgtgaactc ctttaacagc tcgcgctttg gcatcaactg gcagggtttt
    31741 accaccaaat ggtatagcct gctgatgaac aacgacagcc tgttacaggc agcgcagcat
    31801 tcactaacaa tggcggtgtt ttcggcgaca tttgctacgc ttatcggttc actgacggca
    31861 gttgcgctgt accgttatcg ctttcgtggt aagccgttcg ttagcggaat gctgtttgtg
    31921 gtgatgatgt caccagatat cgtgatggcg atttctctgc tggtgctgtt tatgctgctg
    31981 ggtattcagc ttggcttctg gtcgctgctg ttctcgcata tcaccttctg cctgccgttt
    32041 gtggtggtga cggtgtattc gcgcctgaaa ggttttgacg tgcggatgct ggaagcggcg
    32101 aaagatctcg gtgccagtga atttaccatt ctgcgaaaaa tcattctgcc actggcaatg
    32161 cctgcggtgg cggcgggctg ggtgttaagc tttaccctgt cgatggacga tgtggtagtt
    32221 tcttcgttcg tcaccggacc aagttatgaa attctgccgt taaaaattta ttcgatggtc
    32281 aaagtcggcg tatcgccgga agttaacgcg ctggcaacca tattactggt gctgtcgctg
    32341 gtgatggtta ttgccagcca gcttattgct cgtgataaaa cgaaaggtaa cacaggggac
    32401 gttaaatgaa aaaatggtca cgccacctgc tcgcggcggg tgctctggca ctgggcatga
    32461 gcgccgctca cgccgatgac aacaacacgc tgtatttcta caactggacc gagtacgtgc
    32521 cgccaggact gcttgaacag ttcaccaaag aaaccggtat taaggttatc tattcgactt
    32581 acgagtcgaa cgaaaccatg tacgccaagc tgaaaacgta caaagacggt gcctatgacc
    32641 tggtggttcc ttcaacctat tacgtcgata aaatgcgtaa agaagggatg atccagaaga
    32701 tcgacaagtc gaagttaacg aacttcagca atctcgatcc agacatgctc aacaagccgt
    32761 ttgacccgaa taacgattac tccattccgt atatctgggg tgcgacggcg attggtgtta
    32821 acggtgatgc ggtggatccg aaatctgtca ccagctgggc cgatctgtgg aagcctgagt
    32881 acaaaggcag cctgctgttg accgacgatg cccgtgaagt gttccagatg gcgctgcgta
    32941 agctgggcta ctccggtaac accaccgatc cgaaagagat tgaagctgca tataacgagc
    33001 tgaaaaaact gatgccaaac gtcgcagcgt ttaactccga taacccagct aacccgtaca
    33061 tggaaggcga agttaacctc ggcatgatct ggaacggttc tgctttcgtt gcacggcagg
    33121 cgggtacgcc aattgacgtg gtgtggccga aagaaggcgg cattttctgg atggacagcc
    33181 tggcgatccc ggcaaatgcc aaaaacaaag aaggcgcgct gaaattgatc aacttcctgc
    33241 tgcgcccgga tgtggcaaaa caggttgctg aaactatcgg ttatccaacg ccaaaccttg
    33301 cggcgcgtaa gctgttaagc ccggaagtgg cgaacgataa aacgctctac ccggatgctg
    33361 aaaccattaa aaatggtgaa tggcagaatg acgttggcgc agccagcagc atttatgaag
    33421 agtattatca gaagctgaaa gcaggacgtt aattcagcaa gcgggcggtg gcattaccgc
    33481 ccgtttttta tttagcaagg atgtggctaa tgagtcagga cagtaaagtg ttatcccgcg
    33541 cttttctcgg tatcggtctg atattgctcg ttatttctgc aatcatcttt tattaccatt
    33601 ttacttttac caaaagcgcg gttcatacag aaggaatcat tgttgatgcc gtttggtaca
    33661 acaatcactc aaacgacgtc gatgataatg gttcctggta tccagtggtt gcctttcgcc
    33721 ctacgccaga ttacacgcta attttcaatt cgaatatcgg tagtgatttt tatgaagata
    33781 gcgaaggtga cagagtcaat gtctattatc cgccagggca tccagaacaa gccgaaataa
    33841 acaatccctg ggttaatttt tttaaatggg gctttgttgg catagcaggc attattttcg
    33901 gtagtgtcgg tctgataatc acgctcccct ccaccaaaaa atctcgcagg aaacggaagt
    33961 cccgcccatg aaaaaattca ttatactgct cagtttactg atactcctgc ctctggtagc
    34021 aaccagtaaa ccattgattc caataatgaa gacacttttt acggatgtta ccggtactgt
    34081 accggatgct gaagagatcg cacgtaaagc cgagcttttt cgccaacaaa cgggaattgc
    34141 accgtttatt gtgattttac ccgacattaa taatgaagcc agtctcagac aaaatggtaa
    34201 agcgatgctg gcgcatgcgt catcttcatt gagtaatgta aaaggaagtg ttctgttact
    34261 atttactacc cgcgaaccac ggttaattat gatcaccaac ggctaggttg aaagtggtct
    34321 ggacgataaa catctcggcc ttctgataga aaatcacacg ctggcttatt taaatgcaga
    34381 tctctggtat cagggaatca ataatgcatt ggctgttcta caagcacaga tattaaaaca
    34441 accgacgccg ccactgacgt attatccgca tccaggacaa cagcatgaaa atgctccccc
    34501 cggcagcacc aacacattag gttttatcgc ctgggctgcg acgtttatct tattttcctg
    34561 gatcttttgc tacacgactc gttttattta tgcgttaaaa tttgcagtgg cgatgactat
    34621 tgccaatatg ggttatcagg ctttatgttt gtatatcgat aatagctttg cgattaccag
    34681 aatatcgcca ctctgggcag ggctaattgg tgtctgtacg tttattgccg cattgttatt
    34741 gacgagtaaa cgataaaaga ggccggaaaa gtgcgcgtgt attatgccgg atggggcgcg
    34801 aacgccttat ccggcccaca aaacccgcaa attcaattaa ttgcgtcccc ttgtaggcct
    34861 gataagcgta gcgcatcagg caatgcttcc tgctttataa tcccttcagc aacttttcaa
    34921 caaactcagg caccacctgg cttgccgggc cgtaatattt ctcggcaaat tcattaccga
    34981 cctgacttgg ttcgagattc agttccacgg tgtgcgcgcc atgcagtttc gcttcgtgaa
    35041 caaacccagc cgccggataa acatgcccgg aagtaccaat ggcaatgaaa atatcagcca
    35101 tcgacaacgc catataaatt tcatccatgc cgagtggcat ttcgccaaac caaacgacgt
    35161 gcgggcgcaa gggtgccggg aactggcaac aatggcattt atcttctggc gtaacgtctc
    35221 cggtccagtc gagaacctga ccactttgcg aacaacgaac tttcagcaat tccccatgca
    35281 tatgaatgac attggtatta cctgcgcgtt catgcaggtt gtctatattc tgcgttacca
    35341 gcaaaaagcg atcgccgagg gcgtcttgca gtttagccag cgcaagatgc gcggcgttag
    35401 gctgaatttc tggctgctgc agctgtcgac gacgggcgtt ataaaacgct tgcaccagtt
    35461 caggatcgcg atcgaaacct tccggcgttg ccacatcttc aacccgatgt tcttcccaca
    35521 ggccatctgc ggcgcgaaag gtacgaatac ctgattccgc agaaatccct gcccctgtca
    35581 gtacgagtac tcttggtttt tccattgctt ccggcaccac tttatctctg aaaaaaatac
    35641 gctgacgcaa acgctcgcgc aggcggcgtt tatttttacg aaaacgactt aaccgatgac
    35701 cccgacgcga cagcatagca acctctgttg tttaatcggt tagatgtagg aaggccgcac
    35761 cacgcattcc tcccgcatca ccgtggcgcg cgcgttcaat gcgcggaaca cgagctacag
    35821 gtaagagatg acgaggcagc ctgtccgcca gttgcgttgt gattgccggg aaattcgata
    35881 agccaccacc aatgacgacc aggtcagggt caacaatggt caggatattt cccagacaaa
    35941 ccgctaataa atccagataa cgctcaacgt gcgcccttgc ctgctcatcg ccttgatcat
    36001 aaagcgcaat aatttcggga gcctgcaacg gttgatgata atagtgttga tacagccacg
    36061 caaaaccgcg accagacaga taattttcaa tgcagccatg ctgaccacag ccgcagcggc
    36121 gtaacgggaa atccaacccc atcatggtta acgcatcaac cggcagacgc atatggccaa
    36181 actcgccggt aatgtagctt ttaccggtaa tcggtttgcc gttgaaaatc agcctgccgc
    36241 caacgccggt gccgagaatc aaccccatca ccagtggata ttgagtaaat tcatcatccc
    36301 aggcttctga aagggcaaaa cagttggcat cgttatcaag gcgtacatcg cgatcaagac
    36361 gtgcgctcag gtcggcacgc agcggtttac cgctggcagc ggggacattg gcggcataca
    36421 gcgtaccatc ttctgtttcc ggcattcccg gaataccgat gccgacagaa cctttacagc
    36481 caaaacgttg gtcagcttca gctaccagct cacacactgc atctaaaaat gcgtcatagc
    36541 tgtcacgcgg tgtcggcacc cgcttttccc actgcaactg ccgaccgcta tcaaacacgc
    36601 caagcgcaat ttttgttcca ccaatatcaa acccgtaata cattgccgct ccttgtttta
    36661 atgtactgcc tttactggcc gctaaggact cgcgcagggt caatattact ggcgcgccgc
    36721 gccggatacc aacttgccaa aagactcagc aacaatgctg tgaccagtac gtagaagacg
    36781 tccagccagt gcaattccga tggcaggaaa tcaataaaat agatatcgct ggagaggaac
    36841 tgatgaccga tcaacttttc aatccactca ataatcgggg taagttgcag tgaaaccacc
    36901 acaccgataa tcaccccaca caggctgccg aacagccctg ccagcaatcc ataccagaca
    36961 aagatggcgc gaattaaacc atctttcgcc cccagcgttc ttaatactgc gatatcgcca
    37021 ctcttgtctt tcaccgccat cactaaggtg gagacgatgt tgaaacaggc cacgccaatc
    37081 accagtacca tcgccagata cataatggcg cggatcatct ggatatcgcg atacatatag
    37141 ccgtaagtac caatccaact tttaatataa acatagctgt tggtcacttc acccgcatcg
    37201 cgtaccagct tattggcgtt gaaaacatcc gtcattttaa gggcaatacc tgacacgctg
    37261 gaacccatat caagatattg ttgggcatcc gccagcggga tcatggcaaa actgtgatcg
    37321 agttgaccac tcaactgcaa aataccggca acgtgcaaac gcacacgttt tggctgcatc
    37381 agtttatgct cgggattcga gttggggatc ataatcgaca cccaatcccc ctgcttcact
    37441 ttcagcgcat ccgccacgcc tttgccgatg ataatttgct gttcgcccgc tttaaaattg
    37501 cgccacgcat cgccctggac aaacgagggt aatgcgctca gacgctgttc ctgttgcggg
    37561 ttaacgccct tcacctggat tgcgcgaaga ttcacgccac tttccaccag cccggtgaaa
    37621 ttgatatacg gcgcggcagc ggcaataccc ggcacttttt gcacgtgatc cagtgcttcc
    37681 tgccagttag tccacggctg atccaccgcc tcgatttcac catgcggcac caccgccaga
    37741 atacggttgt tcagttcgcg ttcaaagccg ttcatcgcgc ttaagccgac gatcaatacc
    37801 gccacgccga gggcaatgcc aatggtagaa ataacggaga tcagcgacac catgccgccg
    37861 cgccgccgtc cgcgactaaa acgcaggcca attaataacg ataaaggcat cgccattact
    37921 ccgcccccat caggctcagt tccgccgtca gacgaccatc acgcatttct aactggcggc
    37981 tcatacgttt cgccagttgc aggtcgtgag taaccaccag gaaggcggtg ccctgcaagc
    38041 gattcaattc cccaagcaac tggaagatgc tgtcggcgtt acgcgcatcg aggttaccgg
    38101 taggttcatc cgccagtacc aggcgcgggt tattcaccag cgcacgggca atcgccacac
    38161 gctggcgttc gccgccagaa agttcagatg ggcggtgatt cgcacgatga tccagcccca
    38221 ccgcttttaa catctcaagt gcacggctgt tgatttcagc gggctttttc ttgccaatca
    38281 gcagcggcat agccacgttt tccagggcgg taaaatccgg cagcaggtgg tgaaactgat
    38341 aaataaagcc cagcttctgg ttgcgcagct ctgctttcgc cgccgaagac agtttgctca
    38401 tcggttgacc gttaaagatc acatcgccgg aggttggcgt atccagcccg cccaacaagt
    38461 gcagcaaggt gcttttaccg gaaccagagc taccgacgat cgccatcatt tcaccttcgc
    38521 cgacgctgaa actgacattg tgcagcacat cggtttgcac actgccttcc tgatagcgtt
    38581 tgcacaggtt gtcgcattgc aacaggatct tattcataac gtaaagcctc agcgggttga
    38641 gtggcggcag cgcgccatga agggtaaagc gtagacagca gcgcgatagc catcgccacc
    38701 agcgcaataa caatgacctg taaaggttcg atagcgaccg gcagcgccgc gccatcaagc
    38761 aggacgccga ttatcggcat cagattattt aactggctgg caagcagggc gccaagcgcc
    38821 gctccgagga tcgcaccgat aatcccggcg ctggcccctt gcaccataaa gaccatcatg
    38881 atttgtcgcg gagttaagcc ttgcgtttgc aggatcgcta cttcgccctg cttctccatt
    38941 accatcagcc ctagtgaggt aataatgtta aacgccgcaa cggcgacaat caggctcagc
    39001 agtaaaccca tcatattttt ttccatgcgt acggcctgga acaactcgcc tttacgatca
    39061 cgccagtcct gccatttgct gccttcaggc agtttttgct gacttaatga gtcgactttc
    39121 agcggctcat ccagccacaa acgccagccg gtaatattgc ctgccggata acgcatcaga
    39181 cgcgaggcat cctcaatatt caccagcatt tcatagccat cgacttcact gttggcggcg
    39241 aaagtgccaa tcacattgaa caggcgctgg cttggaatac gccccatcgg cgtgaactgg
    39301 ctggcagatg gtaccatcac gcggatttga tcaccgcgat taacgcctag ctgtgaggca
    39361 agttgttcgc cgaggatgac attatatttc cccggctcga ggtcagtttg tttcacattg
    39421 accagatacg gtgtaagtgg atctttttgc gccgggtcga taccgagcat caccccgacc
    39481 gccacgctgc gcgcgctttg cagtaccaca tcaccggtag taataggtgc gacgcgatta
    39541 acgccgtcca gtttgactgc cgtttccggg agttgctgcg ggttaagaga gccatgctca
    39601 gaagagagaa ttgcctgtgg catcaggcca aggatgttgt tttgcagctc gcgctcaaag
    39661 ccgttcatca ctgacaatac tgtgaccagc gccatcaccc cgagggtaat gccgatggta
    39721 gaaagccagg agacgaaacg accgaagcga tccgctgcac gcccacgcat gtaacgcagg
    39781 ccaataaata gagcgacagg ttggtacatg aaatccgtct ggttgctgta gcaaagacac
    39841 gagtatataa gcgaaagcaa gatgggtaaa cgtctgaact gtaagtgatc gtcagggcta
    39901 atctgaaaag cccccgtgaa tcaatcggct aaattgccat gttttatcat caatcttgcc
    39961 gcctgatctt aatctgaaaa atcatccaat acagacagat acccattaca catagggtca
    40021 taacccgcag gatcaaccgc atgtaaatta aaaaagagcg tgttgtcctg atgaaacaaa
    40081 aagagctatg gattaaccag atcaaagggt tatgtatttg tctggtggtg atttatcact
    40141 cggtcattac cttttatccg catctgacca cttttcagca tccgttatcg gaagtcctga
    40201 gcaaatgctg gatctatttc aatctttacc ttgcaccctt tcgtatgccg gtttttttct
    40261 ttatttccgg ctatttgatt cgccgctata tcgacagcgt accgtgggga aattgtctcg
    40321 ataaacgcat ctggagcatc ttttgggtgc tggcgctttg gggcgtggtg cagtggctgg
    40381 cgttaagtgc gcttaaccag tggctggcac ctgagcgcga tttaagcaac gcttccaatg
    40441 ccgcgtatgc cgattccacc ggtgagttcc tgcacgggat gatcacagcc agcaccagct
    40501 tgtggtatct gtatgcgtta attgtctatt tcgtggtatg taaaattttt agccgtctgg
    40561 cgctgccact attcgccttg tttgtactgc tgagtgtggc ggttaatttc gttcccacgc
    40621 cgtggtgggg aatgaacagt gtgatccgca atttgcctta ttacagcctt ggcgcatggt
    40681 ttggcgcaac attaatgacc tgtgttaaag aggtgccgtt gcgccgccat ctgctgatgg
    40741 cttctttgct taccgttctg gcggtcggtg cctggttgtt tactatctcg ctgctgttgt
    40801 cgctggtatc gattgtggtg atcatgaagc tgttttatca atacgagcaa caattcggta
    40861 tgcgctccac cagcctgctg aatgtgattg gctccaacac cattgctatc tacaccaccc
    40921 atcgcattct ggttgaaata ttcagcttaa ctctgcttgc gcaaatgaac gcagcacgct
    40981 ggtcgccgca agtcgaactg acactcctgc tggtttatcc ctttgtcagt ttgttcatct
    41041 gtactgttgc gggcttgctg gtaagaaaac tttcacagcg tgcattcagc gatctgttgt
    41101 tctccccgcc ttcactgccc gctgccgtca gttactcccg ctaagccatc gccccagccg
    41161 gggcgattca atttgctaaa ccatgtcgat tacggataat gaacagcatt gcttatcaga
    41221 gatatgcccc catatgttga ggcatatcct aacgagaatc tgacaaccgt tatgcctgaa
    41281 caatatcgtt atacgctgcc cgtcaaagcg ggtgagcagc gtctgctggg cgagttaacc
    41341 ggcgcagcct gtgcaacgct ggtagcggaa attgccgaac gtcacgccgg tccggtggta
    41401 ctcattgcac cagatatgca aaatgctctg cgtttgcatg atgaaatcag ccagttcacc
    41461 gatcagatgg tgatgaatct ggcggactgg gaaactcttc cctacgacag tttttcgcct
    41521 catcaggaca ttatctcctc gcgcctttcc accctttacc agctaccgac gatgcagcgt
    41581 ggcgtactga ttgttccggt gaatacgctt atgcagcgcg tttgcccaca cagttttctc
    41641 cacggtcatg cgctggtgat gaaaaaaggt cagcgcctgt cacgagatgc attacgaacc
    41701 caactggaca gcgccggtta tcgccatgtt gaccaggtga tggagcacgg cgaatacgcc
    41761 acgcgcggcg cgttgctgga tctcttcccg atggggagtg agctgcctta tcgtcttgat
    41821 ttctttgatg atgaaatcga cagcctgcgg gtgtttgacg tcgacagcca gcgcacgctg
    41881 gaggaagtag aagcgatcaa tctgctgccc gcgcacgaat ttccgaccga taaagcggca
    41941 attgaactgt tccgcagcca gtggcgcgat accttcgaag tgaagcgcga tccggaacat
    42001 atttaccagc aagtgagtaa aggcacatta cctgccggga tcgagtactg gcagccattg
    42061 ttcttcagcg aaccactgcc gccgctgttc agttatttcc ctgccaatac cttgctcgtg
    42121 aatactggcg atctggaaac cagtgccgaa cgtttccagg ctgacacgct ggcgcgtttt
    42181 gagaatcgcg gcgtcgatcc gatgcgcccg ctgttgccac cacaatcgct ctggctgcgg
    42241 gtggacgagc tcttctcaga gctgaaaaac tggccccggg tgcagctaaa aactgaacat
    42301 ttaccgacaa aagccgcgaa tgccaattta ggtttccaga aactgccaga cctggccgtt
    42361 caggcgcaac aaaaagcgcc gctggatgcg ctgcgtaagt tcctcgagac tttcgacggt
    42421 ccggtggtgt tctcggtaga aagtgaaggt cgccgtgaag cgctgggtga actgctcgca
    42481 cgaattaaaa ttgctccgca acgcattatg cgtcttgatg aagccagcga ccgtgggcgt
    42541 tatctgatga ttggcgctgc cgaacatggt tttgtcgata aggtgcgtaa tctggcgctg
    42601 atctgcgaaa gcgatctgct cggtgaacgt gttgcccgcc gtcgtcagga ttctcgccgc
    42661 accatcaacc ccgatacact gatccgtaac cttgcggagc tgcatattgg tcagccggtg
    42721 gtccatctgg agcacggtgt cgggcgctat gccggaatga ccacgctcga agcgggcggc
    42781 attactggcg agtatttgat gctcacctat gccaacgacg ccaaactgta tgttccggtg
    42841 tcgtcactgc atctgattag ccgttacgca ggtggcgcgg aagaaaacgc cccgctgcat
    42901 aaacttggcg gcgatgcgtg gtcacgcgcg cggcagaaag cggcggaaaa agtgcgtgat
    42961 gtggcggcgg aattgctgga tatctacgcg caacgcgccg ccaaagaggg cttcgcgttt
    43021 aaacacgatc gtgagcagta tcagttgttc tgcgacagct tcccgtttga aaccacgccg
    43081 gatcaggcgc aggccattaa tgcggtactt agcgacatgt gtcagccgct ggcaatggat
    43141 cgtctggtgt gcggcgatgt tggctttggt aaaacagaag tggcgatgcg cgccgctttc
    43201 ctggcagtag ataaccacaa gcaggtggcg gtgttggtgc ctaccaccct tctcgcgcag
    43261 cagcattacg acaacttccg cgaccgtttc gccaactggc cggtacgtat cgaaatgatc
    43321 tcccgtttcc gcagcgccaa agagcagacg caaatccttg cggaagtggc ggaagggaaa
    43381 atcgatattc tgatcggtac gcacaaactg ctgcaaagtg acgtcaagtt taaagattta
    43441 ggcctgctga ttgtcgatga agaacaccgc ttcggggtgc gtcataaaga gcgtattaaa
    43501 gcgatgcgcg cgaacgtgga tattctgacg cttactgcaa cgccgatccc acgtacgctg
    43561 aatatggcaa tgagcggaat gcgtgacctg tcgattatcg ccacgccgcc cgcccgtcgt
    43621 ctggcagtta aaacctttgt ccgtgagtat gacagcctgg tggtccggga ggcgatcctg
    43681 cgtgaaattt tgcgcggagg acaggtttat tatctctaca atgatgtgga aaacattcag
    43741 aaagccgccg aacggctggc agaactggtg ccagaagcgc ggatcgccat cggtcacggg
    43801 cagatgcgcg agcgcgaact ggaacgggtg atgaatgatt tccatcatca acgtttcaac
    43861 gtgctggttt gtaccaccat tatcgaaacc gggatcgaca tcccgacagc caacaccatt
    43921 atcattgaac gtgcggatca cttcggtctg gcgcagctgc accagttacg cggtcgcgtc
    43981 ggacgttcgc atcatcaggc atatgcatgg ttgctgacac cgcatccaaa agcgatgact
    44041 accgatgcac aaaaacgtct tgaagcgatt gcctcgctgg aagatctcgg ggcaggtttt
    44101 gcgctggcaa cgcacgatct ggagattcgc ggcgcgggtg aactgcttgg cgaagaacaa
    44161 agtggctcaa tggaaaccat cggtttctcg ctgtatatgg agttgctgga aaacgccgtc
    44221 gatgcactga aatccggacg cgagccgtcg ctggaagatc tcaccagcca gcaaacagaa
    44281 gtcgagctgc ggatgccgtc gctattgcca gatgatttca ttcctgacgt gaatacgcgt
    44341 ttgtcgttct ataaacgtat tgccagcgcc aaaacggaaa acgaactgga agagatcaaa
    44401 gtcgagctta tcgatcgctt cggcctgctg ccggatccgg cgcgtaccct gctggatgtt
    44461 gcccgtctgc gccagcaagc gcagaaactg gggatcagga agctggaagg taatgagaaa
    44521 ggcggggtga tcgaatttgc cgagaagaat cacgttaatc cggcctggtt gattggtttg
    44581 ctgcaaaaac agccgcagca ttaccgcctt gatggtccga cgcgcctgaa atttattcag
    44641 gatttgagtg agcggaaaac gcgtatcgaa tgggtacgcc agtttatgcg tgaactggaa
    44701 gagaacgcga tcgcttaatg gtaaatcggg ggcgtttctg cgcccccatc tgcaacattt
    44761 acaaattctt tgcacttccc tgcactatcc gacactgtca ccatccataa ttcaggctta
    44821 tctgtttatt acaataacct tatatttatt atggattttt ggtgatgatc aaaacgcgtt
    44881 tttctcgctg gctaacgttt tttacgttcg ccgctgccgt ggcgctggcg ctaccggcaa
    44941 aagccaacac ctggc
//
LOCUS       DAPGUL010000025        43087 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.025, whole genome shotgun sequence.
ACCESSION   DAPGUL010000025 DAPGUL010000000
VERSION     DAPGUL010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 43087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43087
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.025"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            266..1888
                     /locus_tag="RHX21_001556"
     CDS             266..1888
                     /locus_tag="RHX21_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4049 domain-containing protein"
                     /protein_id="HDV1986761.1"
                     /translation="MKIGTVAGTNDSTTTIATNDMVQEHVTNFTKELFGYIANGIGDD
                     ISSIARTMLGEVVEKIDDWQIERFQQSIRDDKISFTIQTNHSEKYSMLSDMRAHILRR
                     DNNYQFIVTINSKNYGCYLDNTDINWCSIVYLLNNMTVNDDANDVAVTESYKPVWDWK
                     ISQFNVSDIKFETMINPQFADRTYFSNCSPVDPTSTRPTYFGDTDGSVGAVLYALFAT
                     GHLRIMAEGENFLSQLLNIEDEVLNVLLRENFNEQLDTNVNTIISILNRRDIVLESLQ
                     PYLVINKDAVTPCTFLGDQTGDRFSNICGDQFIIDLLKRIMSINENVHVLAGNHETNC
                     NGNYMQNFTRMKPLDEDTYAGIKDYPVCFYGPKYKIMANHHGITFDDQRKRYIIGPIT
                     VSSDEMTNALEPVELAAIINKKHHAVINGKKFKNSRAISCRSFNRYFSVSTDYRPKLE
                     ALLACSQMLVINQVVAHNGNGGRECIGETGTVLGLNARDSKHAGRMFSMHNCQINPGA
                     GPEITTPWKSYQHEKNRNGLMPLIRRRTMLQL"
     gene            2254..3321
                     /locus_tag="RHX21_001557"
     CDS             2254..3321
                     /locus_tag="RHX21_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HDV1986762.1"
                     /translation="MDKSKRHLAWWVVGALAVAAVVAWWLLRPAGVPEGFAVSNGRIE
                     ATEVDIASKIAGRIDTILVKEGQFVREGEVLAKMDTRVLQEQRLEAIAQIKEAQSAVA
                     AAQALLEQRQSETRAAQSLVNQRQAELDSVAKRHMRSRSLAQRGAISAQQLDDDRAAA
                     ESARAALESAKAQVSASKAAIEAARTNIIQAQTRVEAAQATERRIAADIDDSELKAPR
                     DGRVQYRVAEPGEVLAAGGRVLNMVDLSDVYMTFFLPTEQAGTLKLGGEARLILDAAP
                     DLRIPATISFVASVAQFTPKTVETSDERLKLMFRVKARIPPELLQQHLEYVKTGLPGV
                     AWVRVNEELPWPDDLVVRLPQ"
     gene            3318..6053
                     /gene="rbbA"
                     /locus_tag="RHX21_001558"
     CDS             3318..6053
                     /gene="rbbA"
                     /locus_tag="RHX21_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated ATPase/putative transporter
                     RbbA"
                     /protein_id="HDV1986763.1"
                     /translation="MTHLELVPVPPVAQLAGVSQHYGKTVALNNITLDIPARCMVGLI
                     GPDGVGKSSLLSLISGARVIEQGNVMVLGGDMRDPRHRRDVCPRIAWMPQGLGKNLYH
                     TLSVYENVDFFARLFGHDKAEREVRINELLTSTGLAPFRDRPAGKLSGGMKQKLGLCC
                     ALIHDPELLILDEPTTGVDPLSRAQFWDLIDSIRQRQSNMSVLVATAYMEEAERFDWL
                     VAMNAGEVLATGSAEELRQQTQSATLEEAFINLLPQAQRQAHQAVVIPPYQPENAEIA
                     IEARDLTMRFGSFVAVDHVNFRIPRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAW
                     LFGQPVDPKDIDTRRRVGYMSQAFSLYNELTVRQNLELHARLFHIPEAEIPARVAEMS
                     ERFKLNDVEDILPESLPLGIRQRLSLAVAVIHRPEMLILDEPTSGVDPVARDMFWQLM
                     VDLSRQDKVTIFISTHFMNEAERCDRISLMHAGKVLASGTPQELVEKRGAASLEEAFI
                     AYLQEAAGQSNEAEAPPVIHDTTHAPRQGFSLRRLFSYSRREALELRRDPVRSTLALM
                     GTVILMLIMGYGISMDVENLRFAVLDRDQTVSSQAWTLNLSGSRYFIEQPPLTSYDEL
                     DRRMRAGDITVAIEIPPNFGRDIARGTPVELGVWIDGAMPSRAETVKGYVQAMHQSWL
                     QDVASRQSTPASQSGLMNIETRYRYNPDVKSLPAIVPAVIPLLLMMIPSMLSALSVVR
                     EKELGSIINLYVTPTTRSEFLLGKQLPYIALGMLNFFLLCGLSVFVFGVPHKGSFLTL
                     TLAALLYIIIATGMGLLISTFMKSQIAAIFGTAIITLIPATQFSGMIDPVASLEGPGR
                     WIGEVYPTSHFLTIARGTFSKALDLTDLWQLFIPLLIAIPLVMGLSILLLKKQEG"
     gene            6053..7177
                     /locus_tag="RHX21_001559"
     CDS             6053..7177
                     /locus_tag="RHX21_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709253.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV1986764.1"
                     /translation="MRHLRNIFNLGIKELRSLLGDKAMLTLIVFSFTVSVYSSATVTP
                     GSLNLAPIAIADMDQSQLSNRIVNSFYRPWFLPPEMITADEMDAGLDAGRYTFAINIP
                     PNFQRDVLAGRQPDIQVNVDATRMSQAFTGNGYIQNIINGEVNSFVARYRDNSEPLVS
                     LETRMRFNPNLDPAWFGGVMAIINNITMLAIVLTGSALIREREHGTVEHLLVMPITPF
                     EIMMAKVWSMGLVVLVVSGLSLVLMVKGVLGVPIEGSIPLFMLGVALSLFATTSIGIF
                     MGTIARSMPQLGLLVILVLLPLQMLSGGSTPRESMPQMVQDIMLTMPTTHFVSLAQAI
                     LYRGAGFEIVWPQFLTLMAIGGAFFTIALLRFRKTIGTMA"
     gene            7236..7511
                     /locus_tag="RHX21_001560"
                     /pseudo
     CDS             7236..7511
                     /locus_tag="RHX21_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312384.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
     gene            7508..7867
                     /locus_tag="RHX21_001561"
     CDS             7508..7867
                     /locus_tag="RHX21_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HDV1986765.1"
                     /translation="MIKLKTPNSMEIAGQPAVITYVPELNAFRGKFLGLSGYCDFVSD
                     SIQGLQKEGELSLREYLEDCKAAGIEPYARTEKIKTFTLRYPESLSERLNNAAAQQQV
                     SVNTYIIETLNERLNHL"
     gene            complement(7987..8388)
                     /gene="nikR"
                     /locus_tag="RHX21_001562"
     CDS             complement(7987..8388)
                     /gene="nikR"
                     /locus_tag="RHX21_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-responsive transcriptional regulator
                     NikR"
                     /protein_id="HDV1986766.1"
                     /translation="MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRSALAQEA
                     TQQHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLK
                     GDMGDVQHFADDVIAQRGVRHGHLQCLPKED"
     gene            complement(8394..9200)
                     /gene="nikE"
                     /locus_tag="RHX21_001563"
     CDS             complement(8394..9200)
                     /gene="nikE"
                     /locus_tag="RHX21_001563"
                     /EC_number="7.2.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel import ATP-binding protein NikE"
                     /protein_id="HDV1986767.1"
                     /translation="MTLLNVCGLSHHYAHGGFSGKHQHQAVLNNVSLTLKSGETVALL
                     GRSGCGKSTLARLLVGLESPSQGNISWRGEPLAKLNRAQRKAFRRDIQMVFQDSISAV
                     NPRKTVREILREPMRHLLSLKKSEQLARASEMLKAVDLDDSVLDKRPPQLSGGQLQRV
                     CLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERF
                     CQRVMVMDNGQIVETQVVGDKLTFSSDAGRVLQNAVLPAFPVRRRTTEKV"
     gene            complement(9197..9961)
                     /gene="nikD"
                     /locus_tag="RHX21_001564"
     CDS             complement(9197..9961)
                     /gene="nikD"
                     /locus_tag="RHX21_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel import ATP-binding protein NikD"
                     /protein_id="HDV1986768.1"
                     /translation="MPQQIELRNIALQAAQPLVHGVSLTLQRGRVLALVGGSGSGKSL
                     TCAATLGILPAGVRQTAGEILADGKPVSPCALRGIKIATIMQNPRSAFNPLHTMHTHA
                     RETCLALGKPADDATLTAAIEAVGLENAARVLKLYPFEMSGGMLQRMMIAMAVLCESP
                     FIIADEPTTDLDVVAQARILDLLESIMQKQAPGMLLVTHDMGVVARLADDVAVMSQGK
                     IVEQGDVETLFNAPKHTVTRSLVSAHLALYGMELAS"
     gene            complement(9961..10794)
                     /gene="nikC"
                     /locus_tag="RHX21_001565"
     CDS             complement(9961..10794)
                     /gene="nikC"
                     /locus_tag="RHX21_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter permease subunit NikC"
                     /protein_id="HDV1986769.1"
                     /translation="MNFFLSSRWSVRLALIIIALLALIALTSQWWLPYDPQAIDLPSR
                     LLSPDTQHWLGTDHLGRDIFSRLMAATRVSLGSVMACLLLVLTLGLVIGGSAGLIGGR
                     VDQATMRVADMFMTFPTSILSFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISL
                     RQREFVLASRLSGAGHVRVFVDHLAGAVIPSLLVLATLDIGHMMLHVAGMSFLGLGVT
                     APTAEWGVMINDARQYIWTQPLQMFWPGLALFISVMAFNLVGDALRDHLDPHLVTEHA
                     H"
     gene            complement(10791..11735)
                     /gene="nikB"
                     /locus_tag="RHX21_001566"
     CDS             complement(10791..11735)
                     /gene="nikB"
                     /locus_tag="RHX21_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter permease subunit NikB"
                     /protein_id="HDV1986770.1"
                     /translation="MLRYVLRRFLLLIPMVLAASVIIFLMLRLGTGDPALDYLRLSNL
                     PPTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDFGISFASQRPVLDDMLNFLPATL
                     ELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSV
                     YLQWLPAMGYGGWQHIILPAVSIAFMSLAINARLLRASMLDVAGQRHVTWARLRGLND
                     KQTERRHILRNASLPMITAVGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPV
                     IQCFTLMMVVVFVVCNLIVDLLNAALDPRIRRHEGAHA"
     gene            complement(11735..13309)
                     /gene="nikA"
                     /locus_tag="RHX21_001567"
     CDS             complement(11735..13309)
                     /gene="nikA"
                     /locus_tag="RHX21_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter, nickel/metallophore
                     periplasmic binding protein"
                     /protein_id="HDV1986771.1"
                     /translation="MLSTLRRTLFALLACASFIVHAAAPDEITTAWPVNVGPLNPHLY
                     TPNQMFAQSMVYEPLVKYQADGSVIPWLAKSWTHSEDGKTWTFTLRDDVKFSNGEPFD
                     AEAAAENFRAVLDNRQRHAWLELANQIVDVKALSKTELQITLKSAYYPFLQELALPRP
                     FRFIAPSQFKNHETMNGIKAPIGTGPWILQESKLNQYDVFVRNENYWGEKPAIKKITF
                     NVIPDPTTRAVAFETGDIDLLYGNEGLLPLDTFARFSQNPAYHTQLSQPIETVMLALN
                     TAKAPTNELAVREALNYAVNKKSLIDNALYGTQQVADTLFAPSVPYANLGLKPRQYDP
                     QKAKELLEKAGWTLPAGKDIREKNGQPLRIELSFIGTDALSKSMAEIIQADMRQIGAD
                     VSLIGEEESSIYARQRDGRFGMIFHRTWGAPYDPHAFLSSMRVPSHADFQAQQGLADK
                     PLIDKEIGEVLATHDETQRQALYRDILTRLHDEAVYLPIIYISMMVVSKPELGNIPYA
                     PIATEIPFEQIKPVKP"
     gene            complement(13420..14007)
                     /gene="acpT"
                     /locus_tag="RHX21_001568"
     CDS             complement(13420..14007)
                     /gene="acpT"
                     /locus_tag="RHX21_001568"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase AcpT"
                     /protein_id="HDV1986772.1"
                     /translation="MYRIVLGKVSTLSAAPLPPGLREQAPQGPRRERWLAGRALLSHT
                     LSPLPEIIYGEQGKPAFAPETPLWFNLSHSGDDITLLLSDEGEVGCDIEVIRPRANWR
                     WLANAVFSLGEHAEMDAVHPDQQLEMFWRIWTRKEAIVKQRGGSAWQIVSVDSTYHSS
                     LSVSHCQLENLSLAICTPTPFTLTADSVQWIDSVN"
     gene            complement(14062..15111)
                     /locus_tag="RHX21_001569"
     CDS             complement(14062..15111)
                     /locus_tag="RHX21_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312350.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDV1986773.1"
                     /translation="METPQPDKTGMHILLKLASLVVILAGIHAAADIIVQLLLALFFA
                     IVLNPLVTWFIRRGVKRPVAITIVVVVMLITLTALVGVLAASFNEFISMLPKFNKELT
                     RKLFKLQEMLPFLNLHMSPERMLQRMDSEKVVTFTTALMTGLSGAMASVLLLVMTVVF
                     MLFEVRHVPYKMRFALNNPQIHIAGLHRALKGVSHYLALKTLLSLWTGVIVWLGLELM
                     GVQFALMWAVLAFLLNYVPNIGAVISAVPPMIQVLLFNGIYECILVGALFLVVHMVIG
                     NILEPRMMGHRLGMSTMVVFLSLLIWGWLLGPVGMLLSVPLTSVCKIWMETTKGGSKL
                     AILLGPGRPKSRLPG"
     gene            15243..16460
                     /locus_tag="RHX21_001570"
     CDS             15243..16460
                     /locus_tag="RHX21_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417930.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1986774.1"
                     /translation="MPEPVAEPALNGLRLNLRIVSIVMFNFASYLTIGLPLAVLPGYV
                     HDVMGFSAFWAGLVISLQYFATLLSRPHAGRYADLLGPKKIVVFGLCGCFLSGLGYLT
                     AGLTASLPVISLLLLCQGRVILGIGQSFAGTGSTLWGVGVVGSLHIGRVISWNGIVTY
                     GAMAMGAPLGVVFYHWGGLQALALIIMGVALVAILLAIPRPTVKASKGKPLPFRAVLG
                     SVWLYGMALALASAGFGVIATFITLFYDAKGWDGAAFALTLFSCAFVGTRLLFPNGIN
                     RIGGLNVAMICFSVEIIGLLLVGVATMPWMAKIGVLLAGAGFSLVFPALGVVAVKAVP
                     QQNQGAALATYTVFMDLSLGVTGPLAGLVMSWAGVPVIYLAAAGLVAIALLLTWRLKK
                     RPPEHVPEAASSS"
     gene            complement(16464..17021)
                     /gene="dcrB"
                     /locus_tag="RHX21_001571"
     CDS             complement(16464..17021)
                     /gene="dcrB"
                     /locus_tag="RHX21_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417929.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage sensitivity protein DcrB"
                     /protein_id="HDV1986775.1"
                     /translation="MRNLVKYVGIGLLVMGLAACDDKDTNATAQGSVAESNATGNPVN
                     LLDGKLSFSLPADMTDQSGKLGTQANNMHVWSDATGQKAVIVIMGDDPKEDLAVLAKR
                     LEDQQRSRDPQLQVVTNKAIELKGHKMQQLDSIISAKGQTAYSSVILGNVGNQLLTMQ
                     ITLPADDQQKAQTTAENIINTLVIQ"
     gene            complement(17094..17759)
                     /locus_tag="RHX21_001572"
     CDS             complement(17094..17759)
                     /locus_tag="RHX21_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine/7-aminomethyl-7-
                     deazaguanine transporter"
                     /protein_id="HDV1986776.1"
                     /translation="MNVFSQTQRYKALFWLSLFHLLVITSSNYLVQLPVSIFGFHTTW
                     GAFSFPFIFLATDLTVRIFGAPLARRIIFAVMIPALLISYVISSLFYMGSWQGFGALA
                     HFNLFVARIATASFMAYALGQILDVHVFNRLRQSRRWWLAPTASTLFGNVSDTLAFFF
                     IAFWRSPDAFMAEHWMEIALVDYCFKVLISIVFFLPMYGVLLNMLLKRLADKSEINAL
                     QAS"
     gene            17980..18225
                     /gene="tusA"
                     /locus_tag="RHX21_001573"
     CDS             17980..18225
                     /gene="tusA"
                     /locus_tag="RHX21_001573"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA"
                     /protein_id="HDV1986777.1"
                     /translation="MTDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIAD
                     DPATTRDIPGFCTFMEHELVAKETDGLPYRYLIRKGG"
     gene            complement(18327..20525)
                     /gene="zntA"
                     /locus_tag="RHX21_001574"
     CDS             complement(18327..20525)
                     /gene="zntA"
                     /locus_tag="RHX21_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase
                     ZntA"
                     /protein_id="HDV1986778.1"
                     /translation="MSTPDNHGKKAPQFAAFKPLTAVQNANDCCCDGACSSSPTLSEN
                     VSGTRYSWKVSGMDCAACARKVENAVRQLAGVNQVQVLFATEKLVVDADNDIRAQVES
                     AVQKAGYSLRDEQAAEEPQASRLKENLSLITLIVMMAISWGLEQFNHPFGQLAFIATT
                     LVGLYPIARQALRLIKSGSYFAIETLMSVAAIGALFIGATAEAAMVLLLFLIGERLEG
                     WAASRARQGVSALMALKPETATRLRNGEREEVAINSLRPGDVIEVAAGGRLPADGKLL
                     SPFASFDESALTGESIPVERATGDKVPAGATSVDRLVTLEVLSEPGASAIDRILKLIE
                     EAEERRAPIERFIDRFSRIYTPAIMAVALLVTLVPPLLFAASWQEWIYKGLTLLLIGC
                     PCALVISTPAAITSGLAAAARRGALIKGGAALEQLGRVTQVAFDKTGTLTVGKPRVTA
                     IHPATGISESELLTLAAAVEQGATHPLAQAIVREAQVAELAIPTAESQRALVGSGIEA
                     QVNGERVLICAAGKHPADAFAGLINELESAGQTVVLVVRNDDVLGIIALQDTLRADAA
                     TAISELNALGVKGVILTGDNPRAAAAIAGELGLEFKAGLLPEDKVKAVTKLNQHAPLA
                     MVGDGINDAPAMKAAAIGIAMGSGTDVALETADAALTHNHLRGLVQMIELARATHANI
                     RQNITIALGLKGIFLVTTLLGMTGLWLAVLADTGATVLVTANALRLLRRR"
     gene            complement(20599..21225)
                     /locus_tag="RHX21_001575"
     CDS             complement(20599..21225)
                     /locus_tag="RHX21_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysoplasmalogenase"
                     /protein_id="HDV1986779.1"
                     /translation="MLWSFIAVCLSAWLSVDASYRGPTWQRWVFKPLTLLLLLLLAWQ
                     APMFDAISYLVLAGLCASLLGDALTLLPRQRLMYAIGAFFLSHLLYTIYFASQMTLSF
                     FWPLPLVLLVLGALLLAIIWTRLEEYRWPICTFIGMTLVMVWLAGELWFFRPTAPALS
                     AFVGASLLFISNFVWLGSHYRRRFRADNAIAAACYFAGHFLIVRSLYL"
     gene            21366..21725
                     /locus_tag="RHX21_001576"
     CDS             21366..21725
                     /locus_tag="RHX21_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2500 domain-containing protein"
                     /protein_id="HDV1986780.1"
                     /translation="MSKPPLFFIVIIGLIIVAASFRFMQQRREKADNDMAPLQQKLVL
                     VSNKREKPINDRRSRQQEVTPAGTSMRYEASFKPQSGGMEQTFRLDAQQYHALTVGDK
                     GTLSYKGTRFVSFVGEQ"
     gene            complement(21728..21997)
                     /locus_tag="RHX21_001577"
     CDS             complement(21728..21997)
                     /locus_tag="RHX21_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1145 family protein"
                     /protein_id="HDV1986781.1"
                     /translation="MLINIGRLLMLCVWGFLILNLVHPFPRPLNIFVNVALIFTVLMH
                     GMQLALLKSTLPKDGPQMTTAEKVRIFLFGVFELLVWQKKFKVKK"
     gene            complement(21987..22583)
                     /gene="rsmD"
                     /locus_tag="RHX21_001578"
     CDS             complement(21987..22583)
                     /gene="rsmD"
                     /locus_tag="RHX21_001578"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase"
                     /protein_id="HDV1986782.1"
                     /translation="MKKPNHSGSGQIRIIGGQWRGRKLPVPDSPGLRPTTDRVRETLF
                     NWLAPVIVDAQCLDCFAGSGALGLEALSRYAAGATLIEMDRAVSQQLIKNLATLKAGN
                     ARVVNSNAMSFLAQKGTPHNIVFVDPPFRRGLLEETINLLEDNGWLADEALIYVESEV
                     ENGLPTVPANWSLHREKVAGQVAYRLYQREAQGESDAD"
     gene            22733..24229
                     /gene="ftsY"
                     /locus_tag="RHX21_001579"
     CDS             22733..24229
                     /gene="ftsY"
                     /locus_tag="RHX21_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HDV1986783.1"
                     /translation="MAKEKKRGFFSWLGFGQKEQTPEKETEVQNEQTVVEEIVQAQEP
                     VKASEQAVEEQPQAHTEAEAETFAADVVEVTEQVAESEKAQPEAEVVAQPEPVVEETP
                     EPVAIEREELPLPEDVNAEEVSPEEWQAEAETVEIVEAAEEEAAKEEITDEELEAQAL
                     AAEAAEEAVIVVPPAEEEQPVEEIAQEQEKPTKEGFFARLKRSLLKTKENLGSGFISL
                     FRGKKIDDDLFEELEEQLLIADVGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEM
                     GEILAKVDEPLNVEGKTPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFR
                     AAAVEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNIDVLIADTAGRLQNKS
                     HLMEELKKIVRVMKKLDVEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLD
                     GTAKGGVIFSVADQFGIPIRYIGVGERIEDLRPFKADDFIEALFARED"
     gene            24232..24900
                     /gene="ftsE"
                     /locus_tag="RHX21_001580"
     CDS             24232..24900
                     /gene="ftsE"
                     /locus_tag="RHX21_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HDV1986784.1"
                     /translation="MIRFEHVSKAYLGGRQALQGVTFHMQPGEMAFLTGHSGAGKSTL
                     LKLICGIERPSAGKIWFSGHDITRLKNREVPFLRRQIGMIFQDHHLLMDRTVYDNVAI
                     PLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLL
                     ADEPTGNLDDALSEGILRLFEEFNRVGVTVLMATHDINLISRRSYRMLTLSDGHLHGG
                     VGHE"
     gene            24893..25951
                     /gene="ftsX"
                     /locus_tag="RHX21_001581"
     CDS             24893..25951
                     /gene="ftsX"
                     /locus_tag="RHX21_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsX"
                     /protein_id="HDV1986785.1"
                     /translation="MNKRDAINHIRQFGGRLDRFRKSVGGSGDGGRNAPKRAKSSPKP
                     VNRKTNVFNEQVRYAFHGALQDLKSKPFATFLTVMVIAISLTLPSVCYMVYKNVNQAA
                     TQYYPSPQITVYLQKTLDDDAAAGVVAQLQAEQGVEKVNYLSREDALGEFRNWSGFGG
                     ALDMLEENPLPAVAVVIPKLDFQGTESLNTLRDRITQINGIDEVRMDDSWFARLAALT
                     GLVGRVSAMIGVLMVAAVFLVIGNSVRLSIFARRDSINVQKLIGATDGFILRPFLYGG
                     ALLGFSGALLSLILSEILVLRLSSAVAEVAQVFGTKFDINGLSFDECLLLLLVCSMIG
                     WVAAWLATVQHLRHFTPE"
     gene            26196..27050
                     /gene="rpoH"
                     /locus_tag="RHX21_001582"
     CDS             26196..27050
                     /gene="rpoH"
                     /locus_tag="RHX21_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoH"
                     /protein_id="HDV1986786.1"
                     /translation="MTDKMQSLALAPVGNLDSYIRAANAWPMLSADEERALAEKLHYH
                     GDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLV
                     SFAVHWIKAEIHEYVLRNWRIVKVATTKAQRKLFFNLRKTKQRLGWFNQDEVEMVARE
                     LGVTSKDVREMESRMAAQDMTFDLSSDDDSDSQPMAPVLYLQDKSSNFADGIEDDNWE
                     EQAANRLTDAMQGLDERSQDIIRARWLDEDNKSTLQELADRYGVSAERVRQLEKNAMK
                     KLRAAIEA"
     gene            27321..28424
                     /gene="livJ"
                     /locus_tag="RHX21_001583"
     CDS             27321..28424
                     /gene="livJ"
                     /locus_tag="RHX21_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     substrate-binding protein LivJ"
                     /protein_id="HDV1986787.1"
                     /translation="MNIKGKALLAGCIALAFSNMALAEDIKVAVVGAMSGPVAQYGDQ
                     EFTGAEQAVADINAKGGIKGNKLQIVKYDDACDPKQAVAVANKVVNDGIKYVIGHLCS
                     SSTQPASDIYEDEGILMITPAATAPELTARGYQLILRTTGLDSDQGPTAAKYILEKVK
                     PQRIAIVHDKQQYGEGLARAVQDGLKKGNANVVFFDGITAGEKDFSTLVARLKKENID
                     FVYYGGYHPEMGQILRQARAAGLKTQFMGPEGVANVSLSNIAGESAEGLLVTKPKNYD
                     QVPANKPIVDAIKAKKQDPSGAFVWTTYAALQSLQAGLNQSDDPAEIAKYLKANSVDT
                     VMGPLTWDEKGDLKGFEFGVFDWHANGTATDAK"
     gene            28574..28840
                     /locus_tag="RHX21_001584"
     CDS             28574..28840
                     /locus_tag="RHX21_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HDV1986788.1"
                     /translation="MSAVKKQRIDLRLTDDDKSMIEEAAAISNQSVSQFMLNSASQRA
                     AEVIEQHRRVILNEESWTRVMDALSNPPSPGEKLKRAAKRLQGM"
     gene            28847..29374
                     /locus_tag="RHX21_001585"
     CDS             28847..29374
                     /locus_tag="RHX21_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDV1986789.1"
                     /translation="MDDLTIEILTDDADYDLQRFDCGEEALNLFLTTHLVRQHRNKIL
                     RAYILCRNTPERQVLGYYTLCGSCFERAALPSKSKQKKIPYKNIPSVTLGRLAIDRSL
                     QGQGWGATLVAHAMKVVWSASLAVGIHGLFVEALNKKAHTFYQSLGFIPLVGENENAL
                     FFPTKSIELLFTQSD"
     gene            complement(29371..29754)
                     /gene="panM"
                     /locus_tag="RHX21_001586"
     CDS             complement(29371..29754)
                     /gene="panM"
                     /locus_tag="RHX21_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase autocleavage activator
                     PanM"
                     /protein_id="HDV1986790.1"
                     /translation="MKLTIIRLENFSDQDRIDLQKIWPEYSPSSLQVDDNHRIYAARF
                     NERLLAAVRVTLSGTEGALDSLRVREVTRRRGVGQYLLEEVLRNNPGVSCWWMADAGV
                     EDRGVMTAFMQALGFTAQQGGWEKR"
     gene            30178..31287
                     /gene="livK"
                     /locus_tag="RHX21_001587"
     CDS             30178..31287
                     /gene="livK"
                     /locus_tag="RHX21_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter substrate-binding protein LivK"
                     /protein_id="HDV1986791.1"
                     /translation="MKRNAKTIIAGMIALAISHTAMADDIKVAVVGAMSGPIAQWGDM
                     EFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVANKIVNDGIKYVIGHLCS
                     SSTQPASDIYEDEGILMISPGATNPELTQRGYQHIMRTAGLDSSQGPTAAKYILETVK
                     PQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKENID
                     FVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDAAEGMLVTMPKRYD
                     QDPANQGIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPLALVKDLKANGA
                     NTVIGPLNWDEKGDLKGFDFGVFQWHADGSSTAAK"
     gene            31335..32261
                     /gene="livH"
                     /locus_tag="RHX21_001588"
     CDS             31335..32261
                     /gene="livH"
                     /locus_tag="RHX21_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter permease LivH"
                     /protein_id="HDV1986792.1"
                     /translation="MSEQFLYFLQQMFNGVTLGSTYALIAIGYTMVYGIIGMINFAHG
                     EVYMIGSYVSFMIIAALMMMGIDTGWLLVAAGFVGAIVIASAYGWSIERVAYRPVRNS
                     KRLIALISAIGMSIFLQNYVSLTEGSRDVALPSLFNGQWVVGHSENFSASITTMQAVI
                     WIVTFLAMLALTIFIRYSRMGRACRACAEDLKMASLLGINTDRVIALTFVIGAAMAAV
                     AGVLLGQFYGVINPYIGFMAGMKAFTAAVLGGIGSIPGAMIGGLILGIAEALSSAYLS
                     TEYKDVVSFALLILVLLVMPTGILGRPEVEKV"
     gene            32258..33535
                     /gene="livM"
                     /locus_tag="RHX21_001589"
     CDS             32258..33535
                     /gene="livM"
                     /locus_tag="RHX21_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     permease LivM"
                     /protein_id="HDV1986793.1"
                     /translation="MKPMHIAMALLSAAMFFILAGVFMGVQLELDGTKLVVDTASDVR
                     WQWVFIGTAVVFFFQILRPAFQKGLKSVSGPKFILPAIDGSTVKQKLFLVALLVLAVA
                     WPFMVSRGTVDIATLTMIYIILGLGLNVVVGLSGLLVLGYGGFYAIGAYTFALLNHYY
                     GLGFWTCLPIAGLMAAAAGFLLGFPVLRLRGDYLAIVTLGFGEIVRILLLNNTEITGG
                     PNGISQIPKPTFFGLEFSRTAREGGWDTFSNFFGLKYDPSDRVIFLYLVALLLVVLSL
                     FVINRLLRMPLGRAWEALREDEIACRSLGLSPRRIKLTAFTISAAFAGFAGTLFAARQ
                     GFVSPESFTFAESAFVLAIVVLGGMGSQFAVILAAILLVVSRELMRDFNEYSMLMLGG
                     LMVLMMIWRPQGLLPMTRPQLKLKNGAAKGEQA"
     gene            33532..34299
                     /gene="livG"
                     /locus_tag="RHX21_001590"
     CDS             33532..34299
                     /gene="livG"
                     /locus_tag="RHX21_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter ATP-binding protein LivG"
                     /protein_id="HDV1986794.1"
                     /translation="MSQPLLSVNGLMMRFGGLLAVNNVNLELYPQEIVSLIGPNGAGK
                     TTVFNCLTGFYKPTGGTILLRDQHLEGLPGQQIARMGVVRTFQHVRLFREMTVIENLL
                     VAQHQQLKTGLFSGLLKTPSFRRAQSEALDRAATWLERIGLLEHANRQASNLAYGDQR
                     RLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNHHNTTILLIEHDMKLVM
                     GISDRIYVVNQGTPLANGTPEQIRNNPDVIRAYLGEA"
     gene            34301..35014
                     /gene="livF"
                     /locus_tag="RHX21_001591"
     CDS             34301..35014
                     /gene="livF"
                     /locus_tag="RHX21_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312328.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter ATP-binding protein LivF"
                     /protein_id="HDV1986795.1"
                     /translation="MEKVMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGK
                     TTLLGTLCGDPRATSGRIVFDDKDITDWQTAKIMREAVAIVPEGRRVFSRMTVEENLA
                     MGGFFAERDQFQERIKWVYELFPRLHERRVQRAGTMSGGEQQMLAIGRALMSNPRLLL
                     LDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVVLS
                     DTGDALLANEAVRSAYLGG"
     gene            35410..36726
                     /gene="ugpB"
                     /locus_tag="RHX21_001592"
     CDS             35410..36726
                     /gene="ugpB"
                     /locus_tag="RHX21_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     substrate-binding protein UgpB"
                     /protein_id="HDV1986796.1"
                     /translation="MKPLHYTASALALGLALMGNAQAVTTIPFWHSMEGELGKEVDSL
                     AQRFNAENPDYKIVPTYKGNYEQNLSAGIAAFRTGNAPAILQVYEVGTATMMASKAIK
                     PVYDVFKEAGIQFDESQFVPTVSGYYSDSKTGHLLSQPFNSSTPVLYYNKDAFKKAGL
                     DPEQPPKTWQDLADYAAKLKASGMKCGYASGWQGWIQLENFSAWNGLPFASKNNGFDG
                     TDAVLEFNKPEQVKHIAMLEEMNKKGDFSYVGRKDESTEKFYNGDCAMTTASSGSLAN
                     IREYAKFNYGVGMMPYDADAKDAPQNAIIGGASLWVMQGKNKETYTGVAKFLDFLAKP
                     ENAAEWHQKTGYLPITKAAYDLTREQGFYEKNPGADTATRQMLNKPPLPFTKGLRLGN
                     MPQIRVIVDEELESVWTGKKTPQQALDTAVERGNQLLRRFEKSTKS"
     gene            36824..37711
                     /gene="ugpA"
                     /locus_tag="RHX21_001593"
     CDS             36824..37711
                     /gene="ugpA"
                     /locus_tag="RHX21_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter permease
                     UgpA"
                     /protein_id="HDV1986797.1"
                     /translation="MSSSRPVFRSRWLPYLLVAPQLIITVIFFIWPAGEALWYSLQSV
                     DPFGFSSQFVGLDNFVALFHDSYYLDSFWTTIKFSTFVTVSGLLVSLFFAALVEYIVR
                     GSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGYDWNHAQNSGQAMFL
                     VVFASVWKQISYNFLFFYAALHSIPRSLIEAAAIDGAGPIRRFFKIALPLIAPVSFFL
                     LVVNLVYAFFDTFPVIDAATSGGPVQATTTLIYKIYREGFTGLDLASSAAQSVVLMFL
                     VIVLTVVQFRYVESKVRYQ"
     gene            37708..38553
                     /gene="ugpE"
                     /locus_tag="RHX21_001594"
     CDS             37708..38553
                     /gene="ugpE"
                     /locus_tag="RHX21_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter permease
                     UgpE"
                     /protein_id="HDV1986798.1"
                     /translation="MIENRPWLTIFSHTMLILGIAVILFPLYVAFVAATLDKQAVYAA
                     PMTLIPGTYLLENIHNIWVNGVGTNSAPFWRMLLNSFVMAFSITLGKITVSMLSAFAI
                     VWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASATATF
                     LFRQFFMTLPDELVEAARIDGASPMRFFCDIVFPLSKTNLAALFVITFIYGWNQYLWP
                     LLIITDVDLGTTVAGIKGMIATGEGTTEWNSVMAAMLLTLIPPVVIVLVMQRAFVRGL
                     VDSEK"
     gene            38555..39625
                     /gene="ugpC"
                     /locus_tag="RHX21_001595"
     CDS             38555..39625
                     /gene="ugpC"
                     /locus_tag="RHX21_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417907.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol 3-phosphate ABC transporter ATP
                     binding protein UgpC"
                     /protein_id="HDV1986799.1"
                     /translation="MAGLKLQAVTKSWDGKTQVIKPLTLDVADGEFIVMVGPSGCGKS
                     TLLRMVAGLERVTEGDIWINDQRVTEMEPKDRGIAMVFQNYALYPHMSVEENMAWGLK
                     IRGMGKQQIAERVKEAARILELDGLLKRRPRELSGGQRQRVAMGRAIVRDPAVFLFDE
                     PLSNLDAKLRVQMRLELQQLHRRLKTTSLYVTHDQVEAMTLAQRVMVMNGGVAEQIGT
                     PVEVYEKPASLFVASFIGSPAMNLLTGRVNNEGTHFELDGGIELPLNGGYRQYAGRKM
                     TLGIRPEHIALSSQAEGGVPLVMDTLEILGADNLAHGRWGEQKLVVRLAHQERPTAGS
                     TLWLHLAENQLHLFDGETGQRV"
     gene            39622..40365
                     /gene="ugpQ"
                     /locus_tag="RHX21_001596"
     CDS             39622..40365
                     /gene="ugpQ"
                     /locus_tag="RHX21_001596"
                     /EC_number="3.1.4.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDV1986800.1"
                     /translation="MSNWPYPRIVAHRGGGKLAPENTLAAIDVGAKYGHKMIEFDAKL
                     SKDGEIFLLHDDNLERTSNGWGVAGELNWQDLLRVDAGSWYSKAFKGESLPLLSQVAE
                     RCREHGMMANIEIKPTTGTGPLTGKMVALAARQLWAGMTPPLLSSFEIDALEAAQLAA
                     PELPRGLLLDEWRDDWRELTARLGCVSIHLNHKLLDKVRVMQLKDAGLRILVYTVNKP
                     QRAAELLRWGVDCICTDAIDVIGPNFTAQ"
     gene            complement(40352..40792)
                     /locus_tag="RHX21_001597"
     CDS             complement(40352..40792)
                     /locus_tag="RHX21_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2756 family protein"
                     /protein_id="HDV1986801.1"
                     /translation="MKRLLILTALLPFVGFAQPINTLNNPNQPGYQIPSQQRMQTQMQ
                     TQQIQQKGMLNQQLKTQTQLQQQHLENQINNNSQRVLQSQPGERNPARQQMLPNTNGG
                     MLNSNRNPDSSLNQQHMLPERRNGDMLNQPSTPQPDIPLKTIGP"
     gene            40912..42654
                     /gene="ggt"
                     /locus_tag="RHX21_001598"
     CDS             40912..42654
                     /gene="ggt"
                     /locus_tag="RHX21_001598"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HDV1986802.1"
                     /translation="MIKPTFLRRVAIAALLSGSCFSAAAAPPAPPVSYGVEEDVFHPV
                     RAKQGMVASVDATATQVGVDILKEGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLIR
                     SKNGNTTAIDFREMAPAKATRDMFLDDQGNPDSKKSLTSHLASGTPGTVAGFSLALDK
                     YGTMPLNKVVQPAFKLARDGFIVNDALADDLKTYGSEVLPNHENSKAIFWKEGEPLKK
                     GDTLVQANLAKSLEMIAENGPDEFYKGTIAEQIAQEMQKNGGLITKEDLAAYKAVERT
                     PISGDYRGYQVYSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYAY
                     ADRSEYLGDPDFVKVPWQALTNKAYAKSIADQIDINKAKPSSEIRPGKLAPYESNQTT
                     HYSVVDKDGNAVAVTYTLNTTFGTGIVAGESGILLNNQMDDFSAKPGVPNVYGLVGGD
                     ANAVGPNKRPLSSMSPTIVVKDGKTWLVTGSPGGSRIITTVLQMVVNSIDYGMNVAEA
                     TNAPRFHHQWLPDELRVEKGFSPDTLKLLEAKGQKVALKEAMGSTQSIMVGPDGELYG
                     ASDPRSVDDLTAGY"
     gene            complement(42692..42976)
                     /locus_tag="RHX21_001599"
     CDS             complement(42692..42976)
                     /locus_tag="RHX21_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhB family protein"
                     /protein_id="HDV1986803.1"
                     /translation="MITYHDAFAKANHYLDDADLPVVITLHGRFSQGWYFCFEAREFL
                     ETGDEAARLAGNAPFIIDKDSGEIHSLGTAKPLEEYLQDYEIKKATFGLP"
BASE COUNT        10164 a        10971 c        11953 g         9999 t
ORIGIN      
        1 ttaaaactcc atgaatacgg tggtatgtct ttttaatcct gccagtattt cataggtttt
       61 cttaatcgat tgtagaggca tgttctgatg acgcctttac aatctttagg gactttctct
      121 gctatgagat aagaaatttc atattatgct ttaaggctga atgatttgtg caaaatataa
      181 ttatttttcc atcgaacatg aggtgtatgt cataagatta aatgttaact atgcattcct
      241 cgcggtgaat tatatgaggt aaaagatgaa aattggaact gtggcaggca ctaacgacag
      301 tacaacgaca atcgcaacaa atgatatggt gcaagagcat gttactaact tcactaaaga
      361 actgtttggg tatattgcaa atggtatagg tgatgatata tcaagtattg ccaggacaat
      421 gctcggtgaa gttgtggaaa aaattgatga ttggcaaata gaacgtttcc aacaatctat
      481 tcgagatgac aaaatatcat ttaccataca aacgaatcat tcagaaaaat atagtatgct
      541 atcggacatg cgcgctcata ttctacgtag ggataataat tatcagttta ttgtgacaat
      601 taatagtaaa aattacggct gctatcttga taataccgat attaattggt gcagcattgt
      661 ttatttactt aataatatga cagtaaatga tgatgctaat gatgttgcag ttactgagtc
      721 gtacaaaccc gtctgggact ggaaaatatc gcaattcaat gtatctgata ttaaattcga
      781 aacaatgata aacccccagt tcgctgacag aacctatttc tccaattgtt cacctgttga
      841 tcccacaagt accagaccaa cctattttgg cgataccgat ggctcagtcg gtgcagtttt
      901 gtacgcgctt tttgcaacgg gacatttgag aatcatggct gaaggagaaa atttccttag
      961 ccagttgctt aatatagaag atgaagttct caacgtattg ctaagggaga actttaatga
     1021 gcaacttgac actaatgtta atacaataat cagtattctg aacagaagag atatagtttt
     1081 agaaagtctt cagccttatt tagttattaa taaagacgct gtgacgccat gtacgtttct
     1141 tggcgaccaa accggcgatc gatttagtaa tatctgtggc gatcaattta tcatcgattt
     1201 gttaaaacgc ataatgagta tcaatgaaaa tgttcatgta ttagctggaa atcatgaaac
     1261 gaattgcaat ggtaactata tgcagaactt cacgcgcatg aaaccacttg atgaggatac
     1321 ctacgctggg ataaaagatt atcctgtatg tttctatggc cccaaataca aaataatggc
     1381 aaatcatcat gggataactt ttgatgatca gcgaaaacgt tacattatag gaccgataac
     1441 agtctctagt gatgaaatga ccaatgctct cgaaccggtc gaattagcgg caattatcaa
     1501 taaaaagcac catgctgtaa ttaatggcaa aaagtttaaa aatagccggg ctatctcttg
     1561 tcgatccttt aatcgttatt tttctgtttc gacagattac agacctaaac ttgaagcact
     1621 attagcatgc tcacaaatgt tagttataaa tcaagttgtt gcacataacg gtaatggtgg
     1681 aagagaatgt ataggtgaaa cggggacagt tttaggtctt aacgcccgtg acagtaaaca
     1741 tgctggaaga atgttcagca tgcataattg ccaaattaac cctggtgcag ggcctgagat
     1801 aaccactccc tggaagtctt accagcatga aaaaaacaga aatggactta tgcctttgat
     1861 tagaaggcgc acaatgttac agctctgaac catagacaac atgaatatta atgttactat
     1921 ctggttgaga ctgttgataa aacgtaaaaa ggaatgctct gttcctgcaa ctgaacaggc
     1981 gtgaaacgcg atccaacagg atggataccg ttttgtcagc cagttttata gatcacactt
     2041 atgagtatgc gtgtttcatt tacggccagg aatgctgatg atgacaacat tactacccgt
     2101 tttcactaag ccttccccgt tggcgctcaa tgctctgcgc gctggtcgta tttgtcgttt
     2161 ccttcttatc ccggatggaa gaatccgctg aacgtcgttc ggcggcagtt gtaacacgcg
     2221 tcgtttgctt acagggatta tggcgggccg attatggata agagtaagcg ccatctggcg
     2281 tggtgggttg tcggggcact ggcggtggct gccgtcgtgg cgtggtggct gttgcgcccg
     2341 gcgggtgtgc cggaaggctt tgctgtcagc aatgggcgca ttgaagcgac ggaagtggat
     2401 atcgccagca aaattgccgg gcgtatcgac accattctgg tgaaagaagg ccagtttgtt
     2461 cgcgaaggtg aagtgctggc gaagatggat actcgcgtgt tgcaggaaca gcgactggaa
     2521 gccatcgcgc aaatcaaaga ggcacaaagc gccgttgccg ccgcgcaggc tttgctggag
     2581 caacgacaaa gcgaaactcg cgccgcgcag tcgctggtta atcaacgcca ggcagaactg
     2641 gactccgtag caaaacgtca tatgcgttcc cgttcactgg cccaacgagg ggctatttct
     2701 gcgcaacagc tggatgacga ccgcgccgcc gctgagagcg cccgagctgc gctggaatcg
     2761 gcaaaagctc aggtttctgc ttctaaagcc gctatagagg cggcacgtac caatatcatt
     2821 caggcgcaaa cccgcgtcga agcggcacaa gccactgaac ggcgcattgc cgcagatatc
     2881 gatgacagcg aactgaaagc cccgcgtgac ggacgcgtgc agtatcgggt tgccgagcca
     2941 ggggaagtgc tggcggcagg cggtcgggtg ctgaatatgg tcgatctcag cgacgtctat
     3001 atgaccttct tcctgccaac cgaacaggcg ggcacgctga aactgggtgg tgaagcccgg
     3061 ctgatcctcg atgccgcgcc agatctgcgt attccggcga ccatcagttt tgtcgccagt
     3121 gtcgcccagt tcacgccaaa aaccgtcgaa accagcgatg aacggctgaa actgatgttc
     3181 cgcgtcaaag cgcgtatccc accggaatta ctccagcagc atctggaata tgtcaaaacc
     3241 ggtttaccgg gcgtagcgtg ggtgcgggtg aatgaagaac ttccgtggcc tgacgacctc
     3301 gtggtgaggt tgccgcaatg acgcatctgg aactggttcc cgtcccgcct gtcgcgcaac
     3361 tggcgggcgt gagccagcat tatggaaaaa ccgttgcgct gaacaatatt actctcgata
     3421 ttccggcccg ctgtatggtc gggctgattg gtccggatgg cgtcgggaag tcgagcttat
     3481 tgtcgttgat ttccggtgcc cgcgtcattg agcagggcaa tgtgatggtg ctgggcggcg
     3541 atatgcgcga cccgaggcat cgccgcgacg tctgcccgcg catcgcctgg atgccgcagg
     3601 ggctgggcaa aaacctctac cacaccttgt cggtgtatga aaacgtcgat tttttcgctc
     3661 gcctgttcgg tcacgacaaa gcggagcggg aagtgcgaat taatgagctg ctgaccagca
     3721 cggggttagc accgtttcgc gatcgtccgg cagggaaact ctccggcggg atgaagcaaa
     3781 aacttgggct gtgctgcgcg ttaatccacg acccggaact gttgatcctt gatgagccaa
     3841 caacgggggt tgacccgctc tcccgcgccc agttctggga tctgatcgac agtattcgtc
     3901 agcggcagag caatatgagc gtgctggtcg ccaccgccta tatggaagag gccgaacgct
     3961 tcgactggct ggtagcgatg aatgccggag aagtgctggc aactggcagc gccgaagagc
     4021 tacggcagca aacgcaaagc gctacgctgg aagaagcatt tataaatctg ttaccgcaag
     4081 cgcaacgcca ggcgcatcag gcggtagtga tcccaccgta tcaacctgaa aacgcagaga
     4141 ttgccatcga agcgcgcgat ctgaccatgc gttttggttc cttcgttgcc gttgatcacg
     4201 ttaatttccg cattccacgc ggggagattt ttggattcct tggttcgaac ggctgcggta
     4261 aatccaccac catgaaaatg ctcaccggac tgctgcccgc cagcgaaggt gaggcgtggc
     4321 tgttcgggca accggttgat ccaaaagata tcgatacccg ccgtcgggtg ggctatatgt
     4381 cgcaggcgtt ttcgctctat aacgaactca ccgtgcggca aaaccttgag ttacatgccc
     4441 gtttgtttca catcccggaa gcggaaattc ccgcaagagt ggctgaaatg agcgagcgtt
     4501 ttaagctcaa cgacgttgaa gatattctgc cggagtcatt gccgctcggc attcgccagc
     4561 ggctttcgct ggcggtggcg gtgattcatc gcccggagat gttaatcctc gatgagccta
     4621 cttctggtgt cgatccggtg gcgagggata tgttctggca gttgatggtc gatctctcgc
     4681 gccaggacaa agtgactatc ttcatctcca cccacttcat gaacgaagcg gaacgttgcg
     4741 accgcatctc actgatgcac gccggaaaag tgcttgccag cggtacaccg caggaactgg
     4801 ttgagaaacg cggagccgcc agtctggaag aggcatttat cgcctatttg caggaagcgg
     4861 caggacagag caacgaagcc gaagcgccgc ccgtgataca cgacaccacc cacgcgccgc
     4921 gtcagggatt tagcctgcgc cgtctgttta gctacagccg ccgcgaagca ctggaactgc
     4981 gacgcgatcc ggtacgttcg acgctggcgc tgatgggaac agtgatcctg atgctgataa
     5041 tgggttacgg catcagtatg gatgtggaaa acctgcgctt tgcggtgctc gaccgcgacc
     5101 agaccgtcag tagccaggcg tggacgctca atctctccgg ttcccgttac tttatcgaac
     5161 agccgccgct caccagttat gacgagcttg atcgtcggat gcgtgcgggc gatataacgg
     5221 tggcaattga gatccctccc aatttcgggc gcgatatcgc gcgtggtacg cctgtggaac
     5281 tcggcgtctg gatcgacgga gcgatgccga gccgtgccga aacggtaaaa ggttacgtgc
     5341 aggcaatgca ccagagctgg ctacaggatg tggcgagccg acaatccaca cccgccagcc
     5401 aaagcgggct gatgaatatt gagacgcgct atcgctataa cccggacgta aaaagcctgc
     5461 cagcgattgt tccggcggtg atcccgcttc tgctgatgat gatcccgtca atgctaagcg
     5521 cccttagcgt ggtgcgggaa aaagagcttg ggtcgattat caacctttac gtgaccccca
     5581 ccacgcgtag tgaatttttg cttggtaaac agttgccata catcgcgctg gggatgctga
     5641 actttttcct gctctgcggc ctgtcggtgt ttgtgtttgg cgtaccgcat aaaggcagtt
     5701 tcctgacgct caccctggcg gcgctgctgt atatcatcat tgccaccgga atggggctgc
     5761 tgatctccac ctttatgaaa agccagattg ccgccatttt cggaacggcg attatcacgt
     5821 tgatcccggc gacacagttt tccgggatga tcgatccggt agcttcgctg gaagggcctg
     5881 gacgttggat cggcgaggtt tacccgacca gtcattttct gactatcgcc cgcggaacgt
     5941 tctcgaaagc gctggatctg actgatttgt ggcaactttt tatcccgttg ctgatagcca
     6001 tcccgctggt gatgggctta agtatcctgc tgctgaaaaa acaggaggga tgatgcgcca
     6061 tttacgcaat atttttaatc tgggtatcaa agagttgcgc agtctgctcg gtgataaagc
     6121 gatgctgacg ctgattgtct tctcgtttac ggtgtcggtg tattcgtcag cgaccgttac
     6181 gccaggatcg ttgaacctcg cgccgatcgc cattgccgat atggatcaat cgcagttatc
     6241 gaaccggatc gttaacagct tctatcgccc gtggtttttg ccaccggaga tgatcaccgc
     6301 cgatgagatg gatgccggac tggacgccgg acgttatacc tttgcgataa atattccgcc
     6361 taattttcag cgtgatgtcc tcgccggacg ccagccggat attcaggtga acgtcgatgc
     6421 cacgcgcatg agccaggcat ttaccggcaa tgggtatatc cagaatatta tcaacggtga
     6481 agtgaacagc tttgtcgcgc gctaccgtga taacagcgaa ccgttggtat cgctggaaac
     6541 ccggatgcgc tttaacccga accttgatcc cgcgtggttt ggcggggtga tggcaatcat
     6601 caacaacatt accatgctgg cgattgtatt gaccggatcg gcgctgatcc gcgagcgtga
     6661 acacggcacg gtggaacact tgttggtgat gccgataacg ccgtttgaga tcatgatggc
     6721 aaaggtctgg tcgatggggc tggtggtgct ggtggtgtcg ggattatcac tggtgctgat
     6781 ggtgaaaggc gtgctgggtg taccgattga aggctcgatc ccgctgttta tgctgggcgt
     6841 ggcgctcagt ctgtttgcca ccacgtcaat cggcattttt atggggacga tagcgcgttc
     6901 aatgccgcaa ctggggctgc tggtgattct ggtgctgctg ccgctgcaaa tgctttccgg
     6961 tggatccacg ccgcgcgaaa gtatgccgca gatggtgcag gacattatgc tgaccatgcc
     7021 gacgacacac tttgttagcc tcgcgcaggc cattctctac cggggtgccg gattcgaaat
     7081 cgtctggccg cagttcctga cgctgatggc aattggcggc gcgtttttca ccatcgcgct
     7141 gctgcgattc aggaagacga ttgggacaat ggcgtaagga agggaaactt gacttcatac
     7201 tgtgatgtca taaagtgaag tcataaggga atgtcatgta aacacaggta caggctttac
     7261 gaaagaaaca aaaaaacaca ctggatcagc tatttaaatc acctttacct caaggaatca
     7321 aatggactga tatagaatct ctggttaaag cgttaggcgg agaaattaag gaaggtaggg
     7381 ggtcgcgctg taagttcata ctaaatatga gcgttgcgtg tttccatcgg cctcatccgt
     7441 cgccagatac cgataaaggc gctgtagaaa gcgtgcgtga ctggttacta agtatagggg
     7501 taaaaccatg atcaaactga agacgccaaa ctctatggag attgccgggc aacctgctgt
     7561 tatcacttac gtgccagaac tgaatgcatt tcgtggcaaa ttcctgggct tgtcaggtta
     7621 ttgtgatttt gtctctgaca gcattcaggg gctgcaaaaa gaaggggaac tttccctgcg
     7681 agagtatctt gaggattgta aagctgcggg tattgagccg tatgcgcgta cagaaaagat
     7741 taagaccttt acgttacgct atccagaatc gctgagtgaa cgccttaata atgcggctgc
     7801 gcagcaacaa gtctctgtta atacctatat tattgaaaca ctgaatgagc gtttgaatca
     7861 tttataaatt ttagcggcgt acattacgca gaatatctgc ctttacagga tctatctatg
     7921 caactgaact taattttata aattaagttc agttaatatc ttttctttcc tcgtttcaga
     7981 aataactcaa tcttccttcg gcaagcactg caaatgcccg tgccgcacgc cgcgctgggc
     8041 gataacgtca tcggcaaaat gctgcacgtc gcccatatca cctttcagca cggcgatttc
     8101 cagacagtcg tcgtgattga tatgcacatg cagcgtggcg acggagagat cgtggtgatg
     8161 gtgctgggtg gagacaatgc ggctggctaa gtcgcgtttt tcgtgttcat acacatagga
     8221 gagcaccgcg aaaccttgcg tgccgtgctg ctgagtggcc tcctgggcca gggcgctacg
     8281 cagaatatcg cggatagctt cggaacggtt gttataacca cgacgctggc tcaggctgtc
     8341 cagcgtctcc agtaaatcgt catcaagcgt gatggtgact cgttgcattt gcgttaaacc
     8401 ttttctgtgg tgcgacggcg cacggggaat gcgggtaata ccgcgttttg tagcacacgt
     8461 ccggcgtcag aggaaaaggt taatttatct cccaccacct gggtttcgac gatttgtccg
     8521 ttgtccatca ccatcacccg ctgacagaag cgttccacca ggcgtaagtc gtgggtgatg
     8581 aacaggcagg cggtgccaaa ctgttgttgt agctttttca gcaggcgaat gacgcccgcc
     8641 tgtaacacga gatcaaggtt agaaacggct tcatccagaa tcagtagttt cggttcgacc
     8701 gccagcgcgc gagccaggca gacgcgctgg agctggccgc cgcttaactg cggtgggcgt
     8761 ttgtcgagaa cgctgtcatc gagatcgacc gccttcagca tttcgctggc gcgcgccagt
     8821 tgttcggatt ttttcagtga tagcaggtgg cgcatcggtt cacgcaggat ctcgcgcacg
     8881 gttttgcgcg gattcacggc gctgatggag tcctgaaata ccatctgaat atcgcggcgg
     8941 aacgctttac gctgggcgcg attgagtttc gccagcggtt cgccgcgcca gctaatattc
     9001 ccttgtgagg gagactctaa gcctaccagc agccgcgcga gggtgctttt tccgcagccg
     9061 ctgcgtccca gcagggcgac ggtttcgccg cttttcaggg tcagggaaac gttattcagc
     9121 accgcctgat gttgatgttt tccgctaaat ccaccgtggg catagtgatg ggaaaggccg
     9181 cagacgttaa gtaaggtcat gatgccagct ccataccgta gagggcgaga tgagcggaaa
     9241 ccaggctgcg cgtcaccgta tgtttggggg cgttaaacag cgtttctaca tcgccctgtt
     9301 cgacaatttt accttgtgac atcaccgcca cgtcatccgc cagacgcgcc acaacgccca
     9361 tatcatgggt gaccagcagc attcccggcg cttgtttttg cataatgctt tccagcagat
     9421 cgaggatgcg cgcctgtgct accacgtcga ggtcggtggt cggttcatcg gcgatgataa
     9481 acggtgattc acacagcacc gccatcgcaa tcatcatgcg ctgcaacatg ccgccgctca
     9541 tctcgaacgg gtacagcttc agcacgcgcg cggcgttttc cagccccacc gcttctatgg
     9601 cagcggtaag cgtagcgtca tcggcgggtt tccctaacgc caggcaggtt tcccgcgcgt
     9661 gggtgtgcat ggtgtgcagt ggattaaagg cgctgcgcgg gttctgcatg atggtggcaa
     9721 ttttgatgcc gcgcagggcg caaggcgaaa ccggtttgcc atcggctaaa atttcccccg
     9781 ccgtctggcg aacgccagcg ggcaaaatgc ccagcgtcgc ggcgcaggtt aatgatttcc
     9841 cgctgccgct accgccgact aacgccagca cgcgcccgcg ttgcagggtt aacgatacac
     9901 cgtgtaccag cggctgcgcg gcctgtagcg cgatattacg tagttcaatc tgttgcggca
     9961 ttagtgtgcg tgctccgtca ccagatgagg atccagatga tcgcgcagtg cgtcacccac
    10021 caggttaaag gccatcacgc tgataaacag cgccagcccc ggccagaaca tttgcagcgg
    10081 ctgggtccag atatactggc gcgcgtcgtt aatcatcacg ccccattcgg cggtcggcgc
    10141 ggtcacaccg aggccaagga aagacatccc cgcgacgtgc agcatcatat ggccgatatc
    10201 cagcgttgcc agcaccagca gcgaagggat caccgcgcct gccagatgat cgacaaacac
    10261 ccgcacatgg cccgcaccgg aaagccgtga cgccagcaca aactcgcgtt ggcgtagtga
    10321 aatcaccagg ctgcgcacca tgcgtgcata ccacgcccag tgcgacaggg cgatggcgat
    10381 aattacgttg gtcagcccgg tgccgagcac gccaaccata aagaacgaca gaatcgaggt
    10441 cgggaaggtc ataaacatat cggcgacgcg catggtggcc tgatcaacgc gtccgccaat
    10501 cagtccggcg ctgccgccaa tcaccagccc taatgtcagc accagcagca ggcaggccat
    10561 taccgaaccg agcgacacgc gggtcgccgc catcagccgc gagaaaatat cacgccctaa
    10621 gtgatcggtg cccagccagt gctgcgtatc cggcgaaagc aggcgcgacg gcagatcaat
    10681 agcctgaggg tcatacggca gccaccactg gctggtaagc gcaatcagcg ccagcagggc
    10741 gataatgatc agcgccaggc gtaccgacca gcgggaagag aggaaaaagt tcacgcgtgc
    10801 gctccttcat gacgacgaat gcgcgggtcc agcgcggcgt tgagcaaatc gacaatcaaa
    10861 ttacagacca caaaaaccac caccatcatc agcgtaaagc actggatcac cggatagtca
    10921 cggttaaaaa tcgccgacac cgcatagcgc ccgacgcccg gccaggcaaa gatgttttcg
    10981 ataatcatcg tcccgccgat cagttcgccg atgtgcatcc ccacggcggt gatcatcggc
    11041 agcgaggcat tgcgcaggat gtggcgacgt tcggtctgtt tgtcgttcag gccgcgcaga
    11101 cgcgcccagg tgacgtgacg ctgaccggcg acgtccagca tactggcgcg cagtaaacgc
    11161 gcgttaatcg ccagcgacat aaaggcaatg gaaaccgcag gcaaaatgat gtgctgccag
    11221 ccgccgtaac ccatcgcggg tagccattgc agatacaccg aaaacgccat caccagtaaa
    11281 aacgccagcc agaagttagg catcgacacg ccaagaaacg cgatgaaacg tacggcgaaa
    11341 tccggcagac ggtcgcggtg gcgcgccgcc cagataccga gcggtacgga agtgagcaga
    11401 attaatacca gcgccgcacc tgcaagttcc agcgtggcgg gcaggaagtt cagcatatcg
    11461 tccagtaccg ggcgttggct ggcgaatgag ataccaaagt caagatgcag cgccttccac
    11521 aaccaggtgc cgtactggac gtacagcggc tgatccagtc ccagcatggt gcgggtagag
    11581 gccagcatct ccggcgtcgg cggcaggtta gacagacgca aataatcgag cgccgggtcg
    11641 ccggtaccga ggcgcagcat cagaaaaatg atcaccgagg cggcgagcac catcgggatc
    11701 agcagcagaa agcggcgtaa tacgtaacgc aacattaagg tttcaccggt ttaatctgtt
    11761 cgaacggaat ttcggtggcg atcggcgcgt aggggatgtt acccagctcc ggttttgata
    11821 ccaccatcat cgagatgtag atgataggca gataaaccgc ctcgtcatgc agacgggtca
    11881 gaatgtcgcg atacagcgcc tgacgttgcg tttcgtcatg ggtcgccagc acttcgccga
    11941 tctctttatc aatcagcggc ttgtcggcta atccttgctg tgcctggaag tcagcgtgcg
    12001 acggtacgcg cattgaactc aggaaggcgt gtggatcgta tggcgcgccc caggtgcggt
    12061 ggaaaatcat gccaaaacga ccgtcgcgct gacgagcata gatactgctc tcttcttcgc
    12121 caatcagcga gacatctgcg ccaatctggc gcatatcagc ctgaatgatt tccgccatcg
    12181 atttgcttaa cgcatcggtg ccgatgaacg acagttcaat gcgcagcggc tgaccatttt
    12241 tctcgcggat gtctttgccc gcaggcagcg tccaaccggc tttttccagc aactctttcg
    12301 ctttctgcgg atcgtactgg cgcggtttca ggccgagatt agcgtaaggc acagaagggg
    12361 caaacagggt gtcggcgacc tgctgggtgc catataacgc gttatcaatc agcgattttt
    12421 tgtttaccgc gtaattaaga gcttcacgta ctgccagctc gttggtgggg gctttggcgg
    12481 tattgagcgc cagcatcacg gtttcgatcg gctgtgacag ttgggtgtgg taagccggat
    12541 tctggctaaa gcgggcgaag gtatcgagcg gtaataaccc ttcgtttccg tacagcaggt
    12601 cgatatcgcc agtttcaaac gccaccgcgc gggtagtcgg gtccgggatg acgttaaagg
    12661 tgatcttttt aatcgctggc ttttcgcccc agtagttttc gttacggacg aagacatcgt
    12721 actgattcag tttcgattcc tgcaaaatcc acggtccggt gccaatcggc gctttaattc
    12781 cgttcatggt ttcatggttt ttaaactgcg agggagcgat aaaacggaaa ggacggggca
    12841 gggccagttc ttgcaggaaa ggatagtagg cgcttttcag ggtaatttgc agctctgttt
    12901 tactgagtgc tttaacatca acaatctggt ttgccagctc cagccaggcg tgacgttgac
    12961 ggttatcgag cactgcgcgg aagttttctg ccgccgcctc ggcatcgaac ggttcaccgt
    13021 tggagaattt cacgtcatca cgcagggtga aggtccaggt tttaccatct tctgaatgag
    13081 tccagctttt tgccagccac gggatcaccg aaccgtctgc ctgatatttc accaatggtt
    13141 cataaaccat gctctgggcg aacatctggt taggcgtgta aaggtgcggg tttagtggcc
    13201 cgacattcac cggccaggcg gtggtgattt catctggtgc agcggcatgg acgataaaag
    13261 acgcacaagc cagcagcgca aatagagtgc ggcggagtgt ggagagcatg gtaaccccaa
    13321 tggattaaaa taggtggcgg aaataagtat gacgatttta agtattcgtc atactgatta
    13381 cctgttctgg atcaatagat gggcagtcgg gtgggcggat cagttaactg aatcgatcca
    13441 ttgcacactg tcggcggtga gcgtaaaggg ggtgggggtg cagatcgcca ggcttaaatt
    13501 ttcaagctga caatggctga ctgacagcga ggagtgatag gtgctgtcta cgctgacgat
    13561 ttgccaggcg ctgccgccac gctgtttaac gatggcttct ttgcgcgtcc agatgcgcca
    13621 gaacatttcc agttgctgat caggatgcac ggcgtccatc tcagcgtgtt ccccgaggct
    13681 gaatacggcg ttcgccagcc agcgccagtt ggcgcgcggg cgaatcactt cgatatcgca
    13741 gccgacttcg ccttcatcac tcaacagcag agtgatatcg tcaccgctat ggcttaagtt
    13801 gaaccatagc ggcgtttccg gcgcgaatgc aggtttgcct tgttcgccat agatgatctc
    13861 cggtagcggg gaaagcgtgt gcgaaagcaa tgcacgcccc gccagccagc gttcgcgtcg
    13921 tggaccttgc ggtgcttgct cgcgtaaacc cggtggcagt ggagctgcgc ttaaggtcga
    13981 aactttcccc agaactatcc gatacatatc agggccaacg tttaatggaa aatgaaagtg
    14041 cgtatcgtat cacttgtcgc ctcatcccgg taaccgactt ttcggtctgc ccggccccag
    14101 taaaatcgcc agtttgctgc cacctttcgt cgtttccatc cagattttac acacgctggt
    14161 taatggcacc gaaagtagca tccctaccgg gccgagcagc catccccaga ttaacaatga
    14221 aagaaatacc accatggtgg acatccccag gcgatggccc atcatccgtg gctctaaaat
    14281 attgccgatg accatatgga caactaaaaa caatgcgccg accagaatac attcgtaaat
    14341 accattaaac agcagcacct gaatcattgg cggtacggcg gaaattaccg cgccgatatt
    14401 gggcacgtag ttaagcaaaa acgccagtac tgcccacatc agcgcaaact gtacccccat
    14461 cagctccagc cccagccaga cgatgacacc tgtccataaa ctgagtagcg tcttcaatgc
    14521 aagatagtgc gaaacgcctt taagtgcgcg gtgtaatccc gcgatgtgaa tctgtggatt
    14581 attcagcgca aaacgcattt tgtaagggac gtggcgcact tcaaacagca taaaaactac
    14641 ggtcatcacc agcaaaagca cgctcgccat tgccccggaa agcccggtca ttagcgctgt
    14701 ggtgaaggta accacttttt ccgagtccat ccgctgcagc attcgctccg gcgacatatg
    14761 caaattaaga aaaggcaaca tctcctgcaa tttaaaaagt ttgcgcgtca gctccttatt
    14821 aaacttcggc agcatagaga taaattcgtt aaacgatgcc gccagtacgc cgaccagcgc
    14881 ggttagtgtg atcagcatca ccaccaccac aatcgtaatg gcaacggggc gttttactcc
    14941 ccgtcgaata aaccaggtaa cgagcgggtt gaggacgatg gcaaaaaaca gcgccagtaa
    15001 cagctgcaca atgatatctg ccgctgcgtg aatgcccgcg aggatcacta ccagcgaggc
    15061 cagcttgagc agaatgtgca tgcccgtttt atcgggttga ggggtttcca ttggggcttc
    15121 cttgtgactt tttgtattaa gtgtagcggg agtcacgcca gcaatattct gattcttact
    15181 gctgattttc acgtcagcac atggtaaaaa tgaaacactg ttgtaaaaat gtggtgatcc
    15241 tcatgcccga acccgtagcc gaacccgcgc taaacggatt gcgcctgaat ttgcgcattg
    15301 tctccattgt catgtttaac ttcgccagct acctcaccat cgggttgccg ctcgctgtat
    15361 taccgggcta tgtccatgat gtgatgggct ttagcgcttt ttgggcagga ttggttatca
    15421 gcctgcaata cttcgccacc ttgctgagcc gccctcatgc cggacgttac gccgatttgc
    15481 tgggacccaa aaagattgtc gtcttcggtt tatgcggctg ctttttgagc ggtctgggat
    15541 atctgacggc aggattaacc gccagtctgc ccgtcatcag cctgttatta ctttgccagg
    15601 gacgcgtgat ccttgggatt gggcaaagtt ttgccggaac gggatcgacc ctgtggggcg
    15661 ttggcgtggt tggctcgctg catatcgggc gggtgatttc gtggaacggc attgtcactt
    15721 atggggcgat ggcgatgggt gcgccgttag gcgtcgtgtt ttatcactgg ggcggcttgc
    15781 aggcgttagc gttaatcatt atgggcgtgg cgctggtggc cattttgttg gcgatcccgc
    15841 gtccgacggt aaaagccagt aaaggcaaac cgctgccgtt tcgcgcggtg cttgggagcg
    15901 tctggctgta cggtatggcg ctggcactgg cttccgccgg atttggcgtc atcgccacct
    15961 ttatcacgct gttttatgac gctaaaggtt gggacggtgc ggctttcgcg ctgacgctgt
    16021 ttagctgtgc gtttgtcggt acgcgtttgt tattccctaa cggcattaac cgtatcggtg
    16081 gcttaaacgt agcgatgatt tgctttagcg ttgagataat cggcctgcta ctggttggcg
    16141 tggcgactat gccgtggatg gcgaaaatcg gcgtcttact ggcgggggcc gggttttcgc
    16201 tggtgttccc ggcattgggt gtagtggcgg taaaagcggt tccgcagcaa aatcaggggg
    16261 cggcgctggc aacttacacc gtatttatgg atttatcgct tggcgtgact ggaccactgg
    16321 ctgggctggt gatgagctgg gcgggcgtac cggtgattta tctggcggcg gcgggactgg
    16381 tcgcaatcgc gttattactg acgtggcgat taaaaaaacg gcctccggaa cacgtccctg
    16441 aggccgcctc atcatcttaa aacttactga ataaccagcg tattaatgat gttttctgcg
    16501 gtggtctgcg ctttttgctg atcgtcagcg ggcagcgtaa tttgcatggt cagcagttga
    16561 ttacccacgt tacccagaat aacggaagag tacgccgtct ggcctttcgc ggagataata
    16621 ctgtctaact gctgcatttt gtgacctttc agctcaatgg ctttattggt taccacttgc
    16681 agctgcggat cgcggctacg ttgctgatct tccagacgct tcgccagcac cgccagatct
    16741 tctttcggat catcgcccat gatgacgatg actgctttct gcccggtggc gtcggaccag
    16801 acatgcatgt tattggcctg cgttcccagc ttaccgctct ggtcggtcat atccgctggc
    16861 agcgagaaac ttaacttgcc atcaagcagg ttgacgggat tcccggtagc gttactttcc
    16921 gcgaccgaac cctgcgccgt agcgttagtg tctttatcat cacaggccgc aagccccata
    16981 accagcaggc caattccgac atatttaacc agattgcgca ttgacttctt cctttcgata
    17041 aacggccata acggctcatt catccatctt atcacaactc tgataacgaa cctttaactc
    17101 gcctgcaaag cgttgatttc ggatttatct gccagtcttt tcaacagcat attgagtaat
    17161 acgccataca ttggcaggaa gaaaacgata ctgattaaca ctttgaaaca gtaatcgacc
    17221 agcgcgattt ccatccagtg ttcagccata aaggcatccg ggctacgcca gaaggcaatg
    17281 aagaaaaagg ccagcgtgtc actgacgtta ccgaacagtg tggacgctgt cggtgccagc
    17341 caccagcggc gactttgacg caggcggtta aaaacgtgca cgtcgaggat ttgccccagc
    17401 gcgtaggcca tgaaactggc ggtggcgata cgggcgacaa acaggttgaa gtgggcgagt
    17461 gcgccgaatc cctgccatga acccatatag aacagcgacg agatgacata ggagattaat
    17521 aacgcaggga tcattaccgc gaagataatg cgtcgggcca gcggtgcgcc aaaaatacgc
    17581 acggtcaggt cggtcgcgag aaagataaac ggaaaactaa acgcgcccca ggtggtatga
    17641 aaaccaaaaa tggagaccgg aagctggacc agatagttac tggaggtgat caccagcaga
    17701 tgaaataacg ataaccagaa caacgcctta tagcgttgag tttgcgagaa aacgttcata
    17761 ttgtaccttt ttgattaacc attggggtga gggaacccaa tacgtacgac acgtctgtta
    17821 tcttaacata ataacgtgct tacccttttt tcgagccgcc gcatgatact gctttacgtt
    17881 gacaatgcaa tggttaattt tcacgcaatc gttaacctgg tttgcttacg gactcacagg
    17941 gcgtaaacta gcgccgtttt tttaagtgat gagaagaaaa tgaccgatct cttttccagc
    18001 cctgaccaca cactcgacgc gcttggcctg cgctgcccgg aaccggtgat gatggtgcgc
    18061 aaaaccgtgc gcaatatgca gcctggcgaa actttactga ttatcgccga cgatccggcg
    18121 acgacccgcg atattcctgg gttttgtacc tttatggaac acgaactggt tgcgaaagag
    18181 acggatggac tgccttatcg ttatttgatt cgtaaaggcg gttgatgggg aaagattggc
    18241 ttcgatgccg ccttttcccc tcaccctaac cctctcccca gaggagcgag gggaccgatc
    18301 gcgctcaatg ttgcgatcgg tttgccttat ctcctgcgca acaatcttaa cgcattcgct
    18361 gttaccagca cggtcgcacc ggtatctgcc agcaccgcca gccatagtcc ggtcatccct
    18421 agcagcgtgg tgacgaggaa gatccctttc agccccagcg caatagtgat gttctggcgg
    18481 atattggcgt gagtggcgcg tgccagttca atcatttgca ccaggccgcg caggtggtta
    18541 tgggttaatg ctgcgtcggc ggtttccagc gccacgtctg tgccactgcc cattgcaatc
    18601 ccaatggcgg cagctttcat cgctggcgcg tcgttaatac catcaccgac catcgccagg
    18661 ggcgcatgtt gattcagctt ggtcaccgct ttgactttat cttccggcaa taggcccgct
    18721 ttaaactcca gccccagctc cccggcaatt gccgccgctg cgcgtggatt atcgccggtg
    18781 aggatcactc ctttaacccc cagcgcgttc agttcactga tggcagttgc tgcgtcggcg
    18841 cgcagggtat cctgcaatgc aatgataccc agcacgtcat cattacgtac taccagcaca
    18901 accgtttgcc cggcgctttc cagttcatta atcaaaccag caaatgcatc agcgggatgt
    18961 ttcccggcag cgcaaatcaa tacgcgctca ccgttaacct gcgcttcaat gccagacccg
    19021 accagcgccc gctgtgattc ggcggtggga atggcgagtt cagcaacctg tgcttcgcgt
    19081 acgatggcct gcgccagtgg atgcgtcgcg ccttgctcga ccgccgccgc cagtgtcagc
    19141 agttcagatt cactaatacc cgttgccgga tgaatcgcgg taacgcgcgg tttaccgacg
    19201 gtcagcgtac cggttttatc aaacgccacc tgagtaacac gacccagctg ttccagcgcc
    19261 gctccgcctt taatcaacgc cccacgacgt gccgctgctg ccagcccgga ggtaatcgcc
    19321 gcgggcgtgg agataactaa cgcacacggg cagccaatca gcagcagcgt caggccttta
    19381 taaatccact cttgccagct ggcggcaaac agcagcggcg gcaccagcgt taccagcagg
    19441 gcgacggcca taattgctgg cgtataaatg cggctgaaac ggtcgataaa ccgctcaatg
    19501 ggggcgcggc gctcttcggc ttcttcgatc agtttcagaa tccggtcaat ggcgctggca
    19561 cccggttctg acagcacttc cagcgttacc agacggtcta cgctggtggc tccagcaggg
    19621 actttatcgc ccgtcgcgcg ctccaccgga atggattctc cggtcagggc gctttcatca
    19681 aaactggcaa acggtgagag caatttaccg tcggcaggca aacgcccacc tgcggcgact
    19741 tcaatcacat cgccagggcg caggctgtta atcgccacct cttcccgctc accgttacgc
    19801 aggcgcgtgg cggtttctgg tttcagcgcc attaacgcgc tgaccccttg acgtgcgcgg
    19861 ctggcggccc agccttccag tcgttcgcca atcaaaaaca gcagcaacac catcgcagct
    19921 tcagccgttg cgccaataaa cagcgcacca atagcggcta cgctcattaa cgtttcaatg
    19981 gcgaagtagc tgccggattt gatcaaccgt aatgcctgac gagcaatcgg gtacagccca
    20041 accagcgtgg tcgcgataaa cgccagttgc ccgaacggat gattgaactg ctccagaccc
    20101 cagctgattg ccatcatcac gattagcgta atcagcgaca gattctcttt caggcgtgat
    20161 gcttgcggtt cttcggcggc ctgttcatcg cgcagggaat agcctgcttt ttgcaccgca
    20221 gattcaactt gtgcacgaat gtcattgtcg gcatcgacca ccagtttttc ggtggcgaac
    20281 aacacctgca cctgattcac gcctgcaagc tggcgcacag cattttctac cttgcgcgca
    20341 caggcggcgc agtccatgcc gctgactttc cagctatagc gggtgccgga gacgttttca
    20401 gagagcgttg gcgagctgga acatgcgccg tcgcagcaac agtcgttggc gttctgtacc
    20461 gcagttagcg gtttgaacgc agcaaattga ggggctttct tgccgtgatt gtcaggagtc
    20521 gacatggcat cctccggtta agttttttct cattaaccga aggatacact ctggagtcga
    20581 ctccagagtc aagttttatc agagatacag cgagcggacg atgaggaagt gaccggcaaa
    20641 gtagcaggcc gcagcaatcg cgttatccgc acggaagcgt cggcgatagt gactacccag
    20701 ccagacaaag ttactgataa acagcaacga agcgccgaca aacgcagaga gcgccggagc
    20761 ggtcggacgg aagaaccaca gttcacctgc cagccacacc atcaccagcg tcatgccgat
    20821 aaacgtgcag ataggccaac gatactcttc cagccgcgtc cagataatcg ccagtaacag
    20881 cgcgcccaga accagcagca ccagtggcag aggccagaag aaagagagcg tcatctgact
    20941 ggcgaaatag atggtgtaca gcaggtgcga gaggaaaaac gcgccgatgg cgtacatcag
    21001 acgttgacgt ggcaacaggg ttagcgcatc gcccagcagt gaggcgcaca gccccgccag
    21061 caccagatag ctaatggcgt cgaacatcgg cgcttgccag gccagtaaca gcaggagaag
    21121 aagggttaat ggtttaaata cccagcgttg ccaggttggc ccacgatacg atgcatccac
    21181 agatagccat gcggaaagac agacagcgat aaacgaccaa agcatcttag ttccttgaat
    21241 tcgttatttt ttcgtaagcg gaatgcctac ggtcttgctt ccagtttagt ggcgagggtg
    21301 gacggatgac aacaccataa ctggcagggt atgcttaatt ccgcattttc cgatgaggga
    21361 taaagatgag caaaccacct cttttcttta ttgttatcat tggcttaatc atcgtcgccg
    21421 catcgtttcg ttttatgcaa caacgacggg aaaaagctga taatgatatg gcaccactcc
    21481 agcaaaagct ggtgttggtg agcaacaagc gggaaaaacc gattaacgat cgccgttcgc
    21541 gccagcagga agtgactccg gcaggcacca gtatgcgcta tgaggcaagc ttcaaaccgc
    21601 aaagcggagg aatggagcag acgtttcgcc tcgacgccca gcagtaccac gccctgacag
    21661 tgggcgataa aggtacgctg agctataaag gaacgcgctt tgtcagcttt gtaggcgaac
    21721 aataaggtta ttttttaact ttaaatttct tctgccagac cagcagttca aacacgccga
    21781 aaaggaaaat ccgtaccttt tcggcggtgg tcatctgcgg gccatctttc ggtaaagtgg
    21841 atttcaatag cgccagctgc ataccatgca tcagcacggt aaaaatcagc gccacgttaa
    21901 cgaaaatatt cagcggacgt gggaagggat gcaccaggtt gaggattaaa aatccccaaa
    21961 cacagagcat taacaaacga ccaatattaa tcagcatcac tttctccttg tgcttcgcgt
    22021 tgatacagcc gataagccac ctgacccgcc actttttccc gatgtaatga ccagtttgcc
    22081 ggaacagtgg gcagaccgtt ttcgacttcg ctttcgacat aaatcagggc ttcgtcagcc
    22141 agccagccgt tatcttccag taaatttatc gtctcttcta acaagccacg gcggaacggt
    22201 ggatcgacaa acacgatatt atgcggtgtg cctttttgcg ccaggaatga cattgcgttg
    22261 ctgttcacca cgcgtgcatt gcctgctttt agtgtcgcca gattcttaat taactgctga
    22321 gaaaccgcgc gatccatctc aatcaacgtg gcccccgcag catagcgcga caacgcttcc
    22381 agccccagcg cgccgctccc ggcgaagcaa tccagacatt gggcgtcaac aatgaccgga
    22441 gccagccagt taaacaacgt ttcgcgtacg cggtcggtgg tggggcgcag acctgggcta
    22501 tcaggaaccg ggagtttacg gcctcgccac tgcccgccaa taatgcggat ttggccgctg
    22561 ccggaatgat tcggtttttt catgataaat tgctcaatcc gccagataac acatacttgc
    22621 aggcggtgat gtgaattaag ttaagtgata gactatttca tcattttttt agctgctatg
    22681 tacatagcgt taacgctgtg ccatgaagca acagcgagga gtgtagtcgc aaatggcgaa
    22741 agaaaaaaaa cgtggctttt tttcctggct gggctttggt caaaaagagc agaccccgga
    22801 aaaagagaca gaagttcaga atgaacaaac ggttgtagaa gaaatcgttc aggcgcaaga
    22861 gcctgtgaag gcttctgaac aagccgtcga agagcagccg caggcgcata ctgaggccga
    22921 ggcggaaact tttgctgccg acgttgtgga agtcactgaa caggttgctg aaagtgaaaa
    22981 agcgcagcct gaagcggaag tcgttgcaca accggaaccg gtcgtagaag aaacgccgga
    23041 gccagtggct atcgaacgtg aagagctgcc gttgccggaa gacgtcaacg ccgaagaggt
    23101 ttcgccagaa gagtggcagg ctgaagcgga aaccgtagag attgtcgaag cggcggaaga
    23161 agaagcggct aaagaagaaa tcaccgacga agagctggaa gcacaggcgc tggctgccga
    23221 agcggcagaa gaagcggtga tagtggttcc tccggcagaa gaagagcagc cggttgaaga
    23281 aattgcccag gagcaggaaa aaccgaccaa agaaggtttc ttcgcgcgcc tgaaacgcag
    23341 cctgttaaaa accaaagaaa atctcggttc cggatttatc agcctgttcc gcggtaaaaa
    23401 aatcgacgat gatctgtttg aagagctgga agaacagctg ttgatcgccg atgtgggcgt
    23461 ggaaaccaca cgtaaaatca tcaccaatct gacggaaggc gcatcccgca agcagcttcg
    23521 tgatgccgag gccctctatg gcctgctgaa agaagagatg ggcgagattc tggcgaaagt
    23581 cgatgagccg ctgaatgttg aaggtaaaac gccgttcgtg atcctgatgg taggcgtcaa
    23641 cggtgtgggt aaaaccacga cgattggtaa gctggcgcgt cagtttgagc agcagggtaa
    23701 atcggtgatg ctggcggcgg gcgatacttt ccgtgcagca gcggttgaac agcttcaggt
    23761 ctgggggcag cgcaacaata ttccggtgat tgcccagcat accggtgcgg attccgcctc
    23821 tgttatcttc gacgccattc aggccgctaa agcgcgtaat atcgacgtcc tgattgccga
    23881 taccgccgga cgcctgcaga acaaatcgca cctgatggaa gagttgaaga aaatcgtccg
    23941 cgtgatgaag aaactcgacg ttgaagcgcc gcatgaagtt atgctgacta tcgatgccag
    24001 caccgggcag aacgcggtaa gccaggccaa actgttccat gaagctgttg gcttaaccgg
    24061 catcacgcta acgaaactgg acggcacggc gaaaggcggg gtaattttct cggtggctga
    24121 ccagtttggt atccctatcc gctacattgg tgtcggcgaa cgtattgagg atttgcgtcc
    24181 gtttaaggcg gacgacttta tagaggcact ttttgcccga gaggattaac aatgattcgc
    24241 tttgaacatg tcagcaaggc ttatctcggt gggagacagg cgctgcaggg cgttacgttc
    24301 catatgcagc cgggtgagat ggcgtttctg accggtcatt ccggcgcagg gaaaagtacc
    24361 ctcctgaagc tgatctgtgg gattgagcgg cccagcgccg ggaaaatctg gtttagcggc
    24421 catgacatca cgcgtctgaa aaaccgtgaa gttccgtttc tgcgccgcca gattggcatg
    24481 attttccagg atcaccatct actgatggac cgtactgtct acgataacgt ggcaatcccg
    24541 ctgattatcg ccggtgccag cggtgacgat attcgtcgcc gggtgtcggc ggcactggat
    24601 aaagtcgggc tactggacaa agcgaagaac ttccctattc agctttctgg cggtgaacaa
    24661 cagcgtgttg gcattgcccg cgcggtggtg aacaagcccg cggtactgct ggcggacgaa
    24721 ccgactggta acctggacga cgcgttgtcg gaagggattc tacgtctgtt tgaagagttt
    24781 aaccgcgttg gggtaaccgt attgatggca acgcacgaca tcaacctgat ctcgcggcgt
    24841 tcctatcgca tgctcaccct gagcgatggt cacttgcatg gaggcgtggg ccatgaataa
    24901 gcgcgatgca atcaatcata ttcggcagtt tggcgggcgt ctggatcgct tccgtaaatc
    24961 ggtcggcggc tctggcgacg gcggtcgtaa cgcgccaaaa cgcgcgaaat cctcgccaaa
    25021 accggtaaat cgcaaaacca acgttttcaa cgaacaggtg cgctatgcct tccacggcgc
    25081 attgcaggat ctgaaaagca aaccgttcgc cacgttttta acggtgatgg ttatcgccat
    25141 ctccctgacg ctgcccagcg tctgttatat ggtgtacaaa aacgttaacc aggcggcgac
    25201 gcaatattat ccgtcaccgc aaatcactgt ttacttgcaa aaaacgctgg acgatgacgc
    25261 cgcagcaggc gtggtagcac agctacaggc cgagcagggc gtggagaaag tgaactatct
    25321 ttctcgtgaa gacgcactgg gcgagttccg taactggtct ggttttggtg gtgcgctgga
    25381 tatgctggaa gaaaacccgc ttccggcagt ggcggtggtg atcccgaaac tcgattttca
    25441 ggggacggaa tcactgaata cgctgcgtga tcgtatcacc cagattaacg gcattgacga
    25501 agtgcggatg gatgacagct ggtttgcccg tctggcggcg ttgaccgggc tggtcgggcg
    25561 cgtttccgcg atgatcggcg tgttgatggt ggcagcagtg ttcctcgtca tcggcaacag
    25621 tgtgcgtctg agcatctttg ctcgccgtga ctccattaac gtgcagaaac tgattggtgc
    25681 gacggatggt ttcatcctgc gcccgttcct gtacggaggc gcattgctgg gattttctgg
    25741 cgcattgctg tcattaattt tgtcagaaat tctggtactg cgtttgtcat cggcggttgc
    25801 agaagtggca caggttttcg gaacgaagtt tgatatcaat ggcttatcgt tcgatgaatg
    25861 cctgctgttg ctgctggttt gctctatgat tggctgggtg gcagcgtggc ttgccacggt
    25921 acaacattta cgccacttta cgcctgaata ataaaagcgt gttatactct ttccctgcaa
    25981 tgggttccgt agcagggaaa gagaccccgt tgtctcttcc cggtatttca tctctatgtc
    26041 acattttgtg cgtaatttat tcacaagctt gcattgaact tgtggataaa atcacggtct
    26101 gataaaacag tgaatgataa cctcgttgct cttaagctct ggcacagttg ttgctaccac
    26161 tgaagcgcca gaagatatcg attgagagga tttgaatgac tgacaaaatg caaagtttag
    26221 ctttagcccc agttggcaac ctggattcct acatccgggc agctaacgcg tggccgatgt
    26281 tgtcggctga cgaggagcgg gcgctggctg aaaagctgca ttaccatggc gatctggaag
    26341 cagctaaaac gctgatcctg tctcacctgc ggtttgttgt tcatattgct cgtaattatg
    26401 cgggctatgg cctgccacag gcggatttga ttcaggaagg taacatcggc ctgatgaaag
    26461 cagtgcgccg tttcaacccg gaagtgggtg tgcgcctggt ctccttcgcc gtccactgga
    26521 tcaaagcaga gatccacgaa tacgttctgc gtaactggcg tatcgtcaaa gttgcgacta
    26581 ccaaagcgca gcgcaaactg ttcttcaacc tgcgtaaaac taagcagcgt ctgggctggt
    26641 ttaaccagga tgaagtcgaa atggtggccc gtgaactggg cgtaaccagc aaagacgttc
    26701 gtgagatgga atcacgtatg gcggcacagg acatgacctt tgacctgtct tccgacgacg
    26761 attccgacag ccagccgatg gcaccggtgc tctatctgca ggataaatca tctaactttg
    26821 ccgacggcat cgaagatgat aactgggaag agcaggcggc aaaccgtctg accgacgcga
    26881 tgcagggtct ggacgaacgc agccaggaca tcatccgtgc gcgctggctg gacgaagaca
    26941 acaagtccac gttgcaggaa ctggctgacc gttacggtgt ttccgccgag cgtgtgcgcc
    27001 agctggaaaa gaacgcgatg aaaaaacttc gcgctgccat tgaagcgtaa tttctactac
    27061 taagcagaga accctggatg agaatccggg gtttttgttt tttgggcctc tacaataatc
    27121 aattccccct ccggcaaaac gtcaatcccc acgcagattg ttaataaact gtcaaaatag
    27181 ctattccaat atcataaaaa tggggtatgt tttagcagag tatgctgcta aagcacgggt
    27241 agtcatgcat aaaacgaaat aaagtgctga atcacaacac cacaacacac gtaataacca
    27301 gaagaatggg gattctcagg atgaacataa agggtaaagc gttactggca ggatgtatcg
    27361 cgctggcatt cagcaatatg gctctggcag aagatattaa agtcgcggtc gtgggcgcaa
    27421 tgtccggtcc ggttgcgcag tacggtgacc aggagtttac cggcgcagag caggcggttg
    27481 cggatatcaa cgctaaaggc ggcattaaag gcaacaaact gcaaatcgta aaatatgacg
    27541 atgcctgtga cccgaaacag gcggttgcgg tggcgaacaa agtcgttaac gacggcatta
    27601 aatatgtgat tggtcacctc tgttcttcat caacgcagcc tgcgtctgac atctacgaag
    27661 acgaaggcat tttaatgatc accccagcgg caaccgcgcc ggagctgacc gcccgtggct
    27721 atcagctgat cctgcgcacc accggcctgg actccgacca ggggccgacg gcggcgaaat
    27781 atattcttga gaaagtgaaa ccgcagcgta ttgctatcgt tcacgacaaa cagcaatacg
    27841 gcgaaggtct ggcgcgagcg gtgcaggacg gcctgaagaa aggcaatgct aacgtggtgt
    27901 tctttgatgg tatcaccgcc ggggaaaaag atttctcaac gctggtggcg cgtctgaaaa
    27961 aagagaatat cgacttcgtt tactacggcg gttatcaccc ggaaatgggg caaatcctgc
    28021 gtcaggcacg cgcggcaggg ctgaaaactc agtttatggg gccggaaggt gtggctaacg
    28081 tttcgctgtc taacattgcg ggcgaatcag cggaagggct gctggtgacc aagccgaaga
    28141 actacgatca ggttccggcg aacaaaccca ttgttgacgc catcaaagcg aaaaaacagg
    28201 atccaagtgg cgcgttcgtc tggaccacct acgccgcgct gcaatctttg caggcgggcc
    28261 tgaatcagtc tgacgatccg gctgaaatcg ccaaatacct gaaagcgaac tcggttgata
    28321 ccgtgatggg gccgctgacg tgggatgaga aaggcgatct gaaaggcttt gagttcggcg
    28381 tatttgactg gcacgccaac ggcacggcaa ccgatgcgaa gtaacagata gataaatgaa
    28441 aatgcccgat gcgctgaact gccatcgggt ttttttgtgt ttgtcgaaat ggttgtagaa
    28501 agattaaaca atccaggata tgcttaatgt acggtgacat accgtacata ttatacggag
    28561 caggagagtt cacatgtctg ctgttaaaaa gcagcgtatc gatctgcgtt taactgacga
    28621 tgacaaaagt atgattgagg aagcggcagc gatatctaat cagtccgtca gccaatttat
    28681 gttgaacagc gcttcgcagc gggctgcgga agtgattgaa cagcatcggc gggtgatcct
    28741 caatgaggaa tcctggacgc gggtgatgga tgcgctgagt aatccaccgt cacctggtga
    28801 aaagctaaaa cgtgcggcaa aacgtcttca gggaatgtaa taatttatgg atgatctgac
    28861 gatagagatt ctgaccgatg atgcagatta tgatctacag cgattcgact gcggcgagga
    28921 agcgttaaat ctctttctga cgacacatct cgttcgtcaa catcgcaaca aaattctgcg
    28981 agcgtatatc ctttgtcgca acactccaga acgtcaggtg ctgggatatt acacattatg
    29041 cggcagttgt tttgaacgag ccgcattgcc ctcgaaatcg aaacagaaaa aaattcccta
    29101 caaaaatatt cccagcgtta ctcttgggcg tctggcaatt gatcgttcat tacaggggca
    29161 gggatgggga gcaacactgg ttgctcatgc catgaaagtc gtctggtcag cctctttagc
    29221 ggtaggtatt cacggtcttt ttgtcgaggc gctgaataaa aaagcccata cgttttatca
    29281 atcgctgggc tttatcccgt tggtcggaga aaacgaaaat gcgttatttt tcccaaccaa
    29341 atccatcgaa ctgcttttca cacagagcga ttaacgcttc tcccagccgc cctgttgcgc
    29401 cgtaaatccc agtgcctgca taaacgccgt catcacaccg cgatcttcca cgcctgcatc
    29461 cgccatccac cagcatgaaa cgccaggatt gttacgcaaa acctcttcca gcagatattg
    29521 ccccacaccg cgacgtcggg tgacttcccg cacacgcagg gaatccagtg ctccctcggt
    29581 gccgcttaag gttacccgta cggcagcgag caggcgctcg ttaaaacgcg cggcgtagat
    29641 acggtggtta tcgtcaacct gtaaagagga aggggaatac tccggccaga ttttttgcag
    29701 gtcaatccgg tcctggtcgc taaagttttc taatcgaatg atggtcagct tcatgggtaa
    29761 cccgtgtaaa tcacaaaagt ggaaccagtg tagcgaaata atttaatcgg aggctttctc
    29821 ttttttattt cttttggcag gtgattaatt ttttaacagc aataattaca aagttaaaac
    29881 attagagaat gaaaaatacc cagcataatc ccctgaatgg tagtgaatta ttccgccctt
    29941 tgtgccgtta ttttatgctg acaaaggcac ttttttctgt ttatctatca ataaattcag
    30001 aatattatct gttcttaatc gactgaaaaa tagggatttt aatcactatt atcacaaaat
    30061 actgcgctaa acccttaatc agacaggcaa aaacagtgca gtataaaaaa agaacagtct
    30121 gatttgttaa cacataaaaa caaagcaaca caacatcacg aatggggatt tttgactatg
    30181 aaacggaatg cgaaaactat catcgcaggg atgattgcac tggcaatttc acacaccgct
    30241 atggctgacg atattaaagt tgccgttgtc ggcgcgatgt ccggcccgat tgcccagtgg
    30301 ggcgatatgg aatttaacgg cgcgcgtcag gcgattaaag acattaatgc caaaggggga
    30361 attaaaggcg ataagctggt gggcgtggaa tatgacgacg cctgcgaccc gaaacaagcc
    30421 gttgcggtcg ccaacaaaat cgttaacgac ggcattaaat acgttattgg tcatctgtgt
    30481 tcttcttcta cccaacctgc gtcagatatc tacgaagacg aaggtattct gatgatctcg
    30541 ccgggagcga ccaacccgga gctgacccaa cgcggttatc aacacattat gcgtactgcc
    30601 gggctggact cttcccaggg gcctacggcg gcaaaataca ttcttgagac ggtgaagccc
    30661 cagcgcatcg ccatcattca cgacaaacaa cagtatggcg aagggctggc gcgttcggtg
    30721 caggacgggc taaaagcggc taacgccaac gtcgtcttct tcgacggtat taccgccggg
    30781 gagaaagatt tctccgcgct gatcgcccgc ctgaaaaaag aaaacatcga cttcgtttac
    30841 tacggcggtt actacccgga aatggggcag atgctgcgcc aggcccgttc cgttggcctg
    30901 aaaactcagt ttatggggcc ggaaggtgtg ggtaacgcat cattgtcgaa tattgccggt
    30961 gatgctgccg aaggcatgtt ggtcactatg ccaaaacgct atgaccagga tccggcaaac
    31021 cagggcatcg ttgatgcgct gaaagcagac aagaaagatc cgtccgggcc ttatgtctgg
    31081 atcacctacg cggcggtgca atctctggcg actgcccttg agcgtactgg cagcgatgag
    31141 ccgctggcgc tggtgaaaga tttaaaagct aacggtgcaa acaccgtgat tgggccgctg
    31201 aactgggatg aaaaaggcga tcttaaggga tttgattttg gtgtcttcca gtggcacgcc
    31261 gacggttcat ccacggcagc caagtgatca tcccaccgcc cgtaaaatgc gggcgggttt
    31321 agaaaggtta ccttatgtct gagcagtttt tgtatttctt gcagcagatg tttaacggcg
    31381 tcacgctggg cagtacctac gcgctgatag ccatcggcta caccatggtt tacggcatta
    31441 tcggcatgat caacttcgcc cacggcgagg tttatatgat tggcagctac gtctcattta
    31501 tgatcatcgc cgcgctgatg atgatgggca ttgataccgg ctggctgctg gtggcggcgg
    31561 gattcgtcgg cgcaatcgtc attgccagcg cctacggctg gagtatcgaa cgggtagcct
    31621 atcgcccggt gcgtaactct aagcgcctga ttgcgctcat ctcggcaatc ggcatgtcca
    31681 tcttcctgca aaactacgtt agcctgaccg aaggttcgcg tgacgtggcg ctgcccagtc
    31741 tgtttaacgg gcagtgggtg gtgggccata gcgaaaactt ctctgcctct attactacca
    31801 tgcaggcggt gatttggatt gttaccttcc tcgccatgct ggcgctgacg attttcattc
    31861 gctattcccg tatggggcgc gcctgtcgtg cctgcgcgga agatctgaaa atggcgagcc
    31921 tgcttggcat caacaccgac cgggtgattg cgctgacctt tgtgattggc gcggcgatgg
    31981 cggcggtggc gggtgtgctg ctcggtcagt tctacggtgt gattaacccc tacatcggct
    32041 ttatggccgg gatgaaagcc tttaccgcgg cggtgctcgg cgggattggc agcattccgg
    32101 gggcgatgat tggcgggctg atcctgggga ttgcggaggc gctctcttct gcctatctga
    32161 gtacggaata taaagatgtg gtctcatttg ccctgctgat cctggtactg ctggtgatgc
    32221 cgaccggtat tctggggcgc ccggaggtag agaaagtatg aaaccgatgc atattgcaat
    32281 ggcgctgctc tctgccgcga tgttctttat cctcgctggc gtctttatgg gcgtacagct
    32341 ggagctggac ggcaccaaac tggtggtcga cacggcttcg gatgtccgtt ggcagtgggt
    32401 gtttatcggc acggcggtgg tctttttctt ccagattttg cgacctgctt tccagaaagg
    32461 gttgaaaagc gtttccgggc cgaagtttat tctgcccgcg attgatggct ccacggtgaa
    32521 gcagaaactg ttcctcgtgg cgctgttggt gcttgcggtg gcgtggccgt ttatggtttc
    32581 acgcgggacg gtggatatcg ccaccctgac catgatctac attatcctcg gcctcgggct
    32641 gaacgtggtg gtagggcttt ccggcctgct ggtgctgggg tacggcggtt tttacgccat
    32701 cggcgcttac acttttgcgc tgctcaatca ctattacggc ttgggcttct ggacctgtct
    32761 gccgattgcc gggttaatgg cagcggcggc gggcttcctg ctcggctttc cggtgctgcg
    32821 tctgcgtggt gattatctgg cgatcgttac cctcggcttc ggcgaaattg tgcgcatatt
    32881 gctgctcaat aacaccgaaa ttaccggcgg cccgaacgga atcagtcaga tcccgaaacc
    32941 gactttcttc ggccttgagt tcagccgtac cgcccgtgaa ggcggttggg acacgttcag
    33001 taatttcttt ggcctgaaat acgatccctc cgatcgcgtc atcttcctgt atctggtggc
    33061 gttgctgctg gtggtgctaa gcctgtttgt cattaaccgc ctgctgcgga tgccgctggg
    33121 gcgtgcgtgg gaagcgttgc gtgaagatga gatcgcctgc cgttcgctgg gcttaagccc
    33181 gcgtcgtatc aagctgaccg cttttaccat cagtgccgcg tttgccggtt ttgccggaac
    33241 gctgtttgct gcgcgccagg gctttgtcag cccggaatcc ttcacctttg ctgaatcggc
    33301 gtttgtactg gcgatagtgg tgctcggcgg tatgggatcg cagtttgcgg tgattctggc
    33361 ggcaattttg ctggtggtgt cgcgcgagtt gatgcgtgat ttcaacgaat acagcatgtt
    33421 aatgctcggt ggtttgatgg tgctgatgat gatctggcgt ccgcagggct tgctgcccat
    33481 gacgcgcccg caactgaagc tgaaaaacgg cgcagcgaaa ggagagcagg catgagtcag
    33541 ccattattat ctgtgaacgg cctgatgatg cgcttcggcg gcctgctggc ggtgaacaac
    33601 gtcaatcttg aactgtaccc gcaggagatc gtctcgttaa tcggccctaa cggtgccgga
    33661 aaaaccacgg tttttaactg cctgaccggt ttctacaaac ccaccggcgg caccatttta
    33721 ctgcgcgatc agcatcttga aggtttaccg gggcagcaaa ttgcccgcat gggcgtggtg
    33781 cgcaccttcc agcatgtgcg tctgttccgt gaaatgacgg taattgaaaa cctgctggtg
    33841 gcgcagcatc agcaactgaa aaccgggctg ttctctggcc tgttgaaaac gccttctttc
    33901 cgtcgcgccc agagcgaagc gctcgaccgc gccgccacct ggcttgagcg cattggtttg
    33961 ctggaacacg ccaaccgtca ggcgagtaac ctggcctatg gtgaccaacg ccgtctggag
    34021 attgcccgct gcatggtgac gcagccggag attttaatgc tcgacgaacc ggcggcaggt
    34081 cttaacccaa aagaaaccaa agagctggat gagctgattg ccgaactgcg caatcatcac
    34141 aacaccacta tcttgttgat tgaacacgat atgaagctgg tgatggggat ttcagaccga
    34201 atttatgtgg tcaatcaggg gacgccactg gcaaacggta cgccggagca aatccgtaat
    34261 aacccggacg tgatccgtgc ctatttaggt gaggcataag atggaaaaag tcatgttgtc
    34321 ctttgacaaa gtcagcgccc actacggcaa aatccaggcg ctgcatgagg tgagcctgca
    34381 tatcaatcag ggcgagattg tcaccctcat tggcgcgaac ggggcgggga aaaccacctt
    34441 gctcggcacg ttatgcggcg atccgcgcgc taccagcggg cgaattgtgt ttgatgataa
    34501 agacattacc gactggcaga cggcgaaaat catgcgcgaa gcggtagcga ttgtcccgga
    34561 agggcgtcgc gtcttctcgc ggatgacggt ggaagagaac ctggcgatgg gcggcttttt
    34621 tgccgaacgc gaccagttcc aggagcgcat aaagtgggtg tatgaactgt ttccacgtct
    34681 gcatgagcgc cgtgttcagc gggcaggcac catgtccggc ggtgagcaac aaatgctggc
    34741 gattggtcgc gcgctgatga gcaacccgcg tttgctgcta cttgatgagc catcgctcgg
    34801 tcttgcgccg attatcatcc agcaaatttt cgacaccatc gagcagctgc gcgagcaggg
    34861 gatgactatc ttcctcgtcg agcagaacgc caaccaggcg ctaaagctgg cggatcgcgg
    34921 ctacgtgctg gaaaacggcc atgtggtgct ctccgatacc ggcgacgcgc tgctggcgaa
    34981 cgaagcagtg agaagtgcgt atttaggcgg gtaataacac gttgattgat aaggagtcaa
    35041 aagactcctt tgagacaggt gacaaatgta aaattgcctg atgcgctgcg cttatcaggc
    35101 ctactgggtg agttgcaata tattgaattt gcacgatctt gtaggccgga taaggcgttt
    35161 acgccgcatc cggcatgaaa cgatgagtaa tctgtagagt ttgattcaga ccttctattt
    35221 tccgcttatc cgtgccccat ctcccatttt ccctcaccca cgccgtcacc gccttgtcat
    35281 ctttctgaca ccttactatc ttacaaatgt aacaaaaaag ttatttttct gtaattcgag
    35341 catgtcatgt taccccgcga gcataaaacg cgtgaattcg cgcattcggt acaacaagag
    35401 agataaacga tgaaaccgtt acattataca gcttcagcac tggcgctcgg actggcgtta
    35461 atggggaatg cacaggcagt gacgaccatt ccgttctggc attctatgga aggggaactg
    35521 ggtaaagagg tggattctct ggcccaacgt tttaacgccg aaaatccgga ttacaaaatt
    35581 gtaccgacct ataaaggcaa ctacgaacag aatttaagcg cggggattgc cgcatttcgt
    35641 accggcaacg ctccggctat tttgcaggtt tatgaagttg gcaccgccac catgatggca
    35701 tcgaaagcca ttaaaccggt atatgacgtg tttaaagagg cggggattca attcgatgag
    35761 tcgcagtttg tgccgacggt ttccggttac tactccgaca gcaaaacggg ccacttactc
    35821 tcccagccat tcaacagctc gacccccgtt ctctattaca acaaagacgc cttcaagaaa
    35881 gcaggattag acccggaaca accgccgaaa acctggcagg atctggcgga ctatgccgcg
    35941 aaactgaaag cctccggtat gaagtgcggc tacgccagcg gctggcaggg ctggatccaa
    36001 ctggaaaact ttagcgcctg gaacggtctg ccgtttgcca gcaaaaacaa cggctttgac
    36061 ggcacggacg cggtgctgga gttcaacaag ccggagcagg tgaaacacat cgccatgctc
    36121 gaggagatga acaagaaggg cgacttcagc tacgtcggtc gtaaggatga atccaccgag
    36181 aagttctata acggtgattg cgcgatgacc accgcctctt ccggttctct cgctaatatt
    36241 cgtgagtacg ccaaatttaa ctatggcgta ggcatgatgc cttacgacgc cgatgcgaaa
    36301 gatgcaccgc aaaacgccat tatcggcggg gccagcctgt gggtgatgca gggcaaaaat
    36361 aaagaaacgt ataccggcgt ggcgaagttc ctcgacttcc tcgcgaagcc agaaaacgct
    36421 gccgagtggc atcagaaaac cggttatctg ccaatcacca aagcagcgta tgacctgacc
    36481 cgtgagcagg gcttttacga gaaaaaccca ggggcggata ccgcgacgcg tcagatgctg
    36541 aataagccgc cgttgccgtt caccaaaggg ctgcgtctgg gcaacatgcc gcagatccgc
    36601 gtgattgtgg atgaagagct ggagagcgtg tggaccggta agaagacacc acagcaggca
    36661 ctggataccg ccgttgagcg tggaaatcag ttgctgcgcc gctttgagaa atcgacgaag
    36721 tcttaatcag tgtaatgtcg gatgcgtttc gcttatctga cctggcatcg cgtgtaggcc
    36781 ggataagcga agcgcatccg gcacagttca ggaattaacc gtaatgtcat catcccgtcc
    36841 ggtgttccgc tcgcgctggc tgccttatct gctggtcgcg ccgcagctca tcatcaccgt
    36901 tatctttttt atctggcctg cgggcgaagc gttgtggtac tcgctacaaa gcgtcgatcc
    36961 gtttggtttc tccagccagt ttgtcggcct ggataacttc gtcgcgctgt ttcatgacag
    37021 ctactatctc gactccttct ggacgacgat aaaattcagc acctttgtca ccgtcagcgg
    37081 tttgctggtg tcgctgttct tcgcggcgtt ggtggagtac atcgtgcgcg gcagccgttt
    37141 ctatcaaacc ttgatgctgc tgccgtatgc cgtggctccc gccgttgccg ccgtattgtg
    37201 gatcttcctg tttaaccccg gtcgtgggct gatcacccat tttctcgctg agttcggtta
    37261 tgactggaac catgcgcaga acagcggtca ggcaatgttt ctggtggtgt ttgcctcggt
    37321 gtggaagcaa atcagctaca actttctgtt cttctatgcc gcgctgcact ccattccccg
    37381 ttcattgatt gaagctgcag ccatcgacgg tgcaggccca attcgccgct tctttaagat
    37441 tgcgctgccg cttatcgctc cggtgagttt cttcctgctg gtagtgaacc tggtgtatgc
    37501 cttcttcgac accttcccgg tgatcgacgc cgccacgtcc ggcgggccgg ttcaggccac
    37561 cacgacgctg atttataaga tctaccgcga aggttttacc ggactggatc tggcttcgtc
    37621 tgccgcacag tcggtggtgt tgatgttcct cgtcatcgtg ctgacggtgg tgcagttccg
    37681 ctatgttgaa agcaaggtgc gttaccaatg attgagaacc gtccgtggct gacgatattc
    37741 agccatacca tgctgatcct cgggatcgcg gtgatcctct tcccgctgta cgtggcgttt
    37801 gtcgcggcga cgctggataa acaggccgtc tatgccgcgc cgatgacgct catccccggc
    37861 acatatctgc tggaaaatat ccacaacatc tgggttaacg gggtaggtac gaatagcgcg
    37921 ccgttctggc ggatgttgct taacagcttt gtgatggcgt tcagcattac gctcggcaaa
    37981 attaccgtct cgatgctctc ggcatttgcc attgtctggt ttcgttttcc gctacgtaac
    38041 ctcttcttct ggatgatttt tatcaccctg atgctgccgg ttgaagtacg tatcttcccg
    38101 acggtggaag tcatcgccaa cctgaagatg ctcgacagct acgccggttt aacgctgccg
    38161 ctgatggcct cggcgaccgc tactttcctg ttccgccagt tctttatgac gctgccggat
    38221 gagctggtgg aagccgcgcg gatcgacggc gcatcgccaa tgcgcttctt ttgcgacatc
    38281 gtttttccgc tctccaaaac taatctggcg gcgctgtttg tgatcacctt tatctacggc
    38341 tggaatcagt atttgtggcc gttgttgatt attaccgacg ttgatctcgg caccaccgtg
    38401 gcagggatca aagggatgat cgccactggc gaaggcacca cggaatggaa ctcagtgatg
    38461 gcggcgatgt tgttaaccct gatcccacca gtagtgattg ttttagtgat gcagcgtgcc
    38521 ttcgtgcgcg gcctggtcga tagtgagaaa taagatggca ggactgaaat tacaggcagt
    38581 aaccaaaagc tgggatggca aaacccaggt cattaaaccg ctgacccttg atgtggcaga
    38641 tggcgaattt atcgtgatgg tcgggccgtc tggctgcggg aaatcgacgc tgctgcgcat
    38701 ggttgccggg ctggagcggg tgaccgaagg cgatatctgg atcaacgacc agcgcgtgac
    38761 cgaaatggag ccgaaagatc gcgggattgc gatggtgttc cagaactacg cgctttatcc
    38821 gcatatgagc gtcgaagaaa acatggcgtg ggggctgaaa attcgcggca tgggcaagca
    38881 gcaaatagcc gagcgcgtta aagaagcggc gcgcattctg gagctggatg gcctgcttaa
    38941 gcgccgcccg cgcgagctat ccggcggtca gcgtcagcgt gtggcgatgg gtcgcgcgat
    39001 tgtgcgcgat ccggcggtgt tcctgtttga tgagccgctc tctaacctcg atgccaagct
    39061 gcgcgtgcag atgcgccttg agctgcaaca gctgcaccgt cgcctgaaaa cgacttcact
    39121 ctacgttact cacgatcagg ttgaagcgat gacgctcgcc cagcgagtaa tggtgatgaa
    39181 cggcggcgtt gccgaacaga ttggcacacc agttgaagtc tacgaaaagc ccgccagcct
    39241 gtttgtagcg agttttatcg gcagtccggc gatgaacctg ctgacaggcc gcgtgaataa
    39301 cgaaggcacg catttcgaac tggacggcgg tattgagctg ccgctaaacg gtggctaccg
    39361 tcagtatgcc gggcgtaaaa tgactctcgg cattcgcccg gaacatattg cgctaagctc
    39421 gcaggcagaa ggcggcgtac cgctggtgat ggacacgctg gagatcctcg gcgcagataa
    39481 cctggcgcac ggacgctggg gcgagcagaa gctggtggtg cgactggcgc atcaggagcg
    39541 cccgacggca ggcagcacgc tgtggctgca tctggcggaa aatcagctgc atctttttga
    39601 tggtgaaaca ggacaacgag tatgagtaac tggccttatc cccgcatcgt cgctcatcgt
    39661 ggcggcggta agctggcccc ggaaaacacc ctggcggcaa tcgacgtcgg ggcaaaatac
    39721 ggtcataaga tgatcgaatt tgacgcgaag ttatcgaaag atggcgagat cttcctgctc
    39781 catgacgaca atctcgaacg caccagcaac ggctggggcg tcgcgggtga actgaactgg
    39841 caggatttac tgcgcgtgga tgcgggcagt tggtacagca aagcgtttaa aggtgagtcg
    39901 ctgccgttgc tttcgcaggt ggcggaacgc tgtcgcgaac acgggatgat ggcgaatatc
    39961 gaaatcaaac ccaccactgg cactggacca ttaacgggca aaatggtggc gctggcggca
    40021 cgccaactgt gggccggtat gacgccgccg ctgctgtcat cgtttgagat tgatgcttta
    40081 gaagctgcac agctggcggc accggaactg ccgcgtggtt tattgcttga tgagtggcgc
    40141 gacgactggc gcgaactgac cgcgcggctg ggctgcgtct ctattcatct caatcataag
    40201 ttactcgata aagtgcgagt gatgcagttg aaagacgccg gactgcggat tctggtttat
    40261 accgtcaata aaccccagcg cgcggcagag ttgctgcgct ggggcgtgga ttgcatctgt
    40321 accgatgcga ttgacgtgat tggtccgaac tttacggccc aatagttttc aacggaatgt
    40381 caggctgcgg cgtgctgggc tgattcagca tgtcgccgtt tctcctctcc ggcagcatat
    40441 gctgctgatt caacgaacta tccggattac ggttgctgtt taacatcccg ccgttggtgt
    40501 tgggcagcat ttgctgccgg gcgggatttc gctcccccgg ctgtgactgc aacacccgct
    40561 gagaattatt gtttatctgg ttttctaaat gctgctgttg caactgagtt tgcgttttca
    40621 gttgctgatt cagcatccct ttttgctgga tttgctgagt ctgcatctgg gtttgcatcc
    40681 gctgctggct gggtatctga taccccggct ggttagggtt gttcagagta ttaatgggct
    40741 gtgcaaagcc gacaaacggc aggagtgccg taagaatcag aagtcgtttc atcgcgtatc
    40801 ctcctctgaa gatatccttt aagtttactc gcttcccgac aaaacgatga ttaattcaga
    40861 gttatatacc aggcttagct ggggttgccc cttaatctct ggagaataac gatgataaaa
    40921 ccgacgtttt tacgccgggt ggccattgct gctctgctct caggaagttg ttttagcgcc
    40981 gccgccgcgc ctcctgcgcc gcccgtctcg tatggtgtgg aggaagatgt cttccacccg
    41041 gtacgcgcga aacagggaat ggtagcgtct gtggacgcca ctgccactca ggtgggggtg
    41101 gatattctca aggagggcgg gaatgccgtt gatgccgccg tggcggtggg ctacgcgctg
    41161 gcggtaacgc atccgcaggc agggaatctg ggcggtggtg gttttatgct gatccgctcg
    41221 aaaaatggca ataccaccgc tatcgatttc cgcgaaatgg cacccgctaa agcgacccgc
    41281 gatatgttcc ttgatgacca gggcaacccg gacagcaaaa aatcactcac ttcgcatctg
    41341 gcttccggca caccaggtac ggtcgctggt ttctcgctgg cgttggataa gtacggcact
    41401 atgccgttga acaaagtggt gcagcccgcg ttcaaactgg cacgcgatgg ttttatcgtt
    41461 aacgatgctt tggcagacga tctcaaaacc tacggtagcg aagtgttgcc gaatcacgaa
    41521 aacagcaaag ctatcttctg gaaagagggc gaaccgctga aaaagggcga cacgctggtg
    41581 caggcgaacc tggcaaagag cctggagatg attgctgaaa acggcccgga cgaattctat
    41641 aaaggcacga ttgcggaaca gatcgcccag gagatgcaga aaaacggtgg cttgatcact
    41701 aaagaagatt tagcggccta taaagcggtc gaacgcactc cgataagcgg cgattatcgc
    41761 gggtatcagg tttactccat gccaccgcca tcctccggcg ggatccatat cgtacaaatc
    41821 ctcaatattc tggaaaactt cgatatgaag aaatacggct ttggcagcgc cgatgcgatg
    41881 caaatcatgg cagaagcgga gaaatacgcc tacgccgacc gctcggaata tcttggcgac
    41941 ccggattttg tcaaagtccc gtggcaggca ctgaccaata aagcctatgc caaatccatt
    42001 gccgatcaaa ttgatatcaa caaagcgaag ccgtccagtg agattcgccc tggcaagctt
    42061 gcgccttatg agagtaatca aactacccat tactctgtag tggataaaga cggtaacgcg
    42121 gtggcggtga cctatacgct gaacaccacc ttcggtacgg gtattgtcgc gggcgagagc
    42181 ggtattctgc ttaataacca gatggatgat ttctccgcca aaccgggcgt accgaacgtt
    42241 tacgggctgg tgggcggtga tgccaacgcc gtcgggccga acaaacgccc gctgtcgtcg
    42301 atgtcgccga ccattgtggt gaaagacggt aaaacctggc tggttaccgg tagcccaggc
    42361 ggtagccgga tcatcactac agtgctgcaa atggtggtga atagcatcga ttatggcatg
    42421 aacgtcgccg aagcgaccaa tgcgccgcgt ttccaccatc agtggttgcc ggacgagctg
    42481 cgtgtcgaaa aagggtttag cccggatacg ctcaagctgc tggaagcaaa aggtcagaaa
    42541 gtggcgctga aagaggcgat gggcagtaca caaagcatta tggttgggcc ggacggtgag
    42601 ttgtacggcg catccgaccc gcgctcggtg gatgatttaa cggcggggta ctaaggttag
    42661 cggccctctt cgtgggaaga gggctatttt gtcagggcaa gccgaaggta gcctttttta
    42721 tttcgtaatc ctgtagatat tcttccagcg gctttgccgt tcccagagaa tgaatttcac
    42781 cactgtcttt atcaataata aaaggtgcgt taccagctaa gcgcgcggcc tcatctccag
    42841 tttcgagaaa ttctcgtgct tcgaaacaga aataccagcc ctggctaaag cgtccatgta
    42901 gagtaatgac gaccgggaga tctgcatcat caaggtaatg gttcgctttc gcgaatgcgt
    42961 cgtgataagt aatcataatt ataataaata ttattgttga gtgttatatt attattcctg
    43021 tgtgatacat tgagcaaaga cgcgttcatc ttcgtcaaag atattattaa atgctggttt
    43081 tgaaaaa
//
LOCUS       DAPGUL010000026        42668 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.026, whole genome shotgun sequence.
ACCESSION   DAPGUL010000026 DAPGUL010000000
VERSION     DAPGUL010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 42668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42668
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.026"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            75..227
                     /gene="hokA"
                     /locus_tag="RHX21_001600"
     CDS             75..227
                     /gene="hokA"
                     /locus_tag="RHX21_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001135724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokA"
                     /protein_id="HDV1986804.1"
                     /translation="MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQGCYELAAFL
                     ACNLKE"
     gene            complement(415..627)
                     /gene="cspA"
                     /locus_tag="RHX21_001601"
     CDS             complement(415..627)
                     /gene="cspA"
                     /locus_tag="RHX21_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone/antiterminator CspA"
                     /protein_id="HDV1986805.1"
                     /translation="MSGKMTGIVKWFNADKGFGFITPDDGSKDVFVHFSAIQNDGYKS
                     LDEGQKVSFTIESGAKGPAAGNVTSL"
     gene            complement(908..1198)
                     /locus_tag="RHX21_001602"
     CDS             complement(908..1198)
                     /locus_tag="RHX21_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator"
                     /protein_id="HDV1986806.1"
                     /translation="MEYKDPMHELLSSLEQIVFKDETQKITLTHRTTSCTEIEQLRKG
                     TGLKIDDFARVLGVSVAMVKEWESRRVKPSSAELKLMRLIQANPALSKQLME"
     gene            1632..2342
                     /locus_tag="RHX21_001603"
     CDS             1632..2342
                     /locus_tag="RHX21_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3053 domain-containing protein"
                     /protein_id="HDV1986807.1"
                     /translation="MATGKSCSRWFAPLAALLMVVSLSGCFDKEGDQRKAFIDFLQNT
                     VMRSGERLPTLTADQKKQFGPFVSDYAILYGYSQQVNQAMDSGLRPVVDSVNAIRVPQ
                     DYVTQSGPLREMNGSLGVLAQQLQNAKLQADAAHSALKQTDDLKPVFDQAFTKVVTTP
                     ADALQPLIPAAQTFTQQLVMVGDYIAQQGTQVSFVANGIQFPTSQQASEYNKLIAPLP
                     AQHQAFNQAWTTAVTATQ"
     gene            complement(2392..3366)
                     /gene="ghrB"
                     /locus_tag="RHX21_001604"
     CDS             complement(2392..3366)
                     /gene="ghrB"
                     /locus_tag="RHX21_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312465.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate/hydroxypyruvate reductase GhrB"
                     /protein_id="HDV1986808.1"
                     /translation="MKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFA
                     EAEGLLGSNENVDAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTET
                     VADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMAL
                     AQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLF
                     GAEQFAKMKSSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLS
                     MANVVAVPHIGSATHETRYGMAACAVDNLIDALQGKVEKNCVNPHVAD"
     gene            complement(3470..4129)
                     /locus_tag="RHX21_001605"
     CDS             complement(3470..4129)
                     /locus_tag="RHX21_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family lipoprotein"
                     /protein_id="HDV1986809.1"
                     /translation="MKKRVYLIAAVVSGALAVSGCTTNPYTGEREAGKSAIGAGLGSL
                     VGAGIGALSSSKKDRGKGALIGAAAGAALGGGVGYYMDVQEAKLRDKMRGTGVSVTRS
                     GDNIILNMPNNVTFDSSSATLKPAGANTLTGVAMVLKEYPKTAVNVIGYTDSTGGHDL
                     NMRLSQQRADSVASALITQGVDASRIRTQGLGPANPIASNSTAEGKAQNRRVEITLSP
                     L"
     gene            4282..6615
                     /gene="bisC"
                     /locus_tag="RHX21_001606"
     CDS             4282..6615
                     /gene="bisC"
                     /locus_tag="RHX21_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418007.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin sulfoxide reductase"
                     /protein_id="HDV1986810.1"
                     /translation="MANSSSRYSVLTAAHWGPMLVETDGETVFSSHGALATGMENSLQ
                     SAVRDQVHSNTRVRFPMVRKGFLASPENPQGIRGQDEFVRVSWDEALDLIHQQHKRIR
                     EAYGPASIFAGSYGWRSNGVLHKASTLLQRYMALAGGYIGHLGDYSTGAAQAIMPYVV
                     GGSEVYQQQTSWPLVLEHSDVVVLWSANPLNTLKIAWNASDEQGLSYFSALRDSGKKL
                     ICIDPMRSETVDFFGDKMEWVAPHMGTDVALMLGIAHTLVENGWHDEAFLTRCTTGYA
                     VFASYLLGESDGIAKNAEWAAEICGVNAAKIRELAALFHQNTTMLMAGWGMQRQQFGE
                     QKHWMIVTLAAMLGQIGTPGGGFGLSYHFANGGNPTRRSAVLSSMQGSLPGGCDAVDK
                     IPVARIVEALENPGGAYQHNGMNRHFPDIRFIWWAGGANFTHHQDTNRLIRAWQKPEL
                     VVISECFWTAAAKHADIVLPATTSFERNDLTMTGDYSNQHLVPMKQVVPPRYEARNDF
                     DVFAELSERWEKGGYARFTEGKSQLQWLETFYNVARQRGASQQVELPPFAEFWQANQL
                     IEMPENPDSERFIRFADFCRDPLAHPLKTASGKIEIFSQRIADYGYPDCPGHPMWLEP
                     DEWQGNAEPEQLQVLSAHPAHRLHSQLNYSSLRELYAVANREPVTIHPDDAQARGITE
                     GDMVRVWNSRGQILAGAVISEGIKPGVICIHEGAWPDLDLTADGICKNGAVNVLTKDL
                     PSSRLGNGCAGNTALAWLEKYNGPELTLTAFEPPASS"
     gene            complement(6584..7024)
                     /locus_tag="RHX21_001607"
     CDS             complement(6584..7024)
                     /locus_tag="RHX21_001607"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDV1986811.1"
                     /translation="MIREAQRSELPAILELWLESTTWGHPFIKANYWRDCIPLVRDAY
                     LANAQNWVWEEDGKLLGFVSIMEGRFLAAMFVAPKAVRRGIGKALMQYVQQRYPHLML
                     EVYQKNQPAIDFYRAQGFHIVDCAWQDETQLPTWIMSWPVVQTL"
     gene            complement(7021..7584)
                     /gene="tag"
                     /locus_tag="RHX21_001608"
     CDS             complement(7021..7584)
                     /gene="tag"
                     /locus_tag="RHX21_001608"
                     /EC_number="3.2.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HDV1986812.1"
                     /translation="MERCGWVSQDPLYIAYHDNEWGVPETDSKKLFEMICLEGQQAGL
                     SWITVLKKRENYRACFHQFDPVKVAAMQEEDVERLVQDAGIIRHRGKIQAIIGNARAY
                     LQMEQNGEPFADFVWSFVNHQPQVTQATTLSEIPTSTSASDALSKALKKRGFKFVGTT
                     ICYSFMQACGLVNDHVVGCCCYPGNKP"
     gene            7742..8440
                     /locus_tag="RHX21_001609"
     CDS             7742..8440
                     /locus_tag="RHX21_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709326.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HDV1986813.1"
                     /translation="MIIKKSGGRWQLSLLASVVISAFFLNTAYAWQQEYIVDTQPGHS
                     TERYTWDSDHQPDYNDILSQRIQSSQRALGLEVNLAEETPVDVTSSMSMGWNFPLYEQ
                     VTTGPVAALHYDGTTTSMYNEFGDSTTTLTDPLWHASVSSLGWRVDSRLGDLRPWAQI
                     SYNQQFGENIWKAQSGLSRMTATNQNGNWLDVTVGADMLLNQNIAAYAALTQAENTTN
                     NSDYLYTMGVSARF"
     gene            8669..9877
                     /locus_tag="RHX21_001610"
     CDS             8669..9877
                     /locus_tag="RHX21_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1986814.1"
                     /translation="MTPSNYQRTRWLTLIGTIITQFALGSVYTWSLFNGALSAKLDAP
                     VSQVAFSFGLLSLGLAISSSVAGKLQERFGVKRVTMASGILLGLGFFLTAHSDNLMML
                     WLSAGVLVGLADGAGYLLTLSNCVKWFPERKGLISAFAIGSYGLGSLGFKFIDTRLLE
                     TVGLEKTFVIWGAIALVMIVFGATLMKDAPKQEVKTSNGVVEKDYTLAESMRKPQYWM
                     LAVMFLTACMSGLYVIGVAKDIAQSLAHLDVVSAANAVTVISIANLSGRLVLGILSDK
                     IARIRVITIGQVISLVGMAALLFAPLNAVTFFAAIACVAFNFGGTITVFPSLVSEFFG
                     LNNLAKNYGVIYLGFGIGSIFGSIIASLFGGFYVTFYVIFALLILSLALSTTIRQPEQ
                     KMLREAHGSL"
     gene            10201..11892
                     /gene="eptB"
                     /locus_tag="RHX21_001611"
     CDS             10201..11892
                     /gene="eptB"
                     /locus_tag="RHX21_001611"
                     /EC_number="2.7.8.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418002.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid A phosphoethanolamine
                     7''-transferase"
                     /protein_id="HDV1986815.1"
                     /translation="MRYIKSITQQKLSFLLAIYIGLFMNGAVFYRRFGSYAHDFTVWK
                     GVSAVVELAATVLVTFFLLRLLSLFGRRSWRILASLVVLFSAGASYYMTFLNVVIGYG
                     IIASVMTTDIDLSKEVVGLNFILWLIAVSALPLILIWNNRCRYTLLRQLRTPGQRIRS
                     LAVVVLAGIMVWAPIRLLDIQQKKVERATGVDLPSYGGVVANSYLPSNWLSALGLYAW
                     ARVDESSDNNSLLNPAKKFTYQAPQNVDDTYVVFIIGETTRWDHMGIFGYERNTTPKL
                     AQEKNLAAFRGYSCDTATKLSLRCMFVRQGGAEDNPQRTLKEQNIFAVLKQLGFSSDL
                     YAMQSEMWFYSNTMADNIAYREQIGAEPRNRGKPVDDMLLVDEMQQSLGRNPDGKHLI
                     ILHTKGSHFNYTQRYPRSFAQWKPECIGVDSGCTKAQMINSYDNSVTYVDHFISSVID
                     QVRDKKAIVFYAADHGESINEREHLHGTPRELAPPEQFRVPMMVWMSDKYLENPANAQ
                     AFAQLKKEADMKVPRRHVELYDTIMGCLGYTSPDGGINENNNWCHIPQTKVAAAN"
     gene            11984..12060
                     /locus_tag="RHX21_001612"
     tRNA            11984..12060
                     /locus_tag="RHX21_001612"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12018..12020,aa:Pro,seq:cgg)
     gene            12095..12228
                     /locus_tag="RHX21_001613"
     ncRNA           12095..12228
                     /ncRNA_class="other"
                     /locus_tag="RHX21_001613"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
     gene            12973..14580
                     /gene="dppA"
                     /locus_tag="RHX21_001614"
     CDS             12973..14580
                     /gene="dppA"
                     /locus_tag="RHX21_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter substrate-binding
                     protein DppA"
                     /protein_id="HDV1986816.1"
                     /translation="MRISLKKSGMLKLGLSLVAMTVAASVQAKTLVYCSEGSPEGFNP
                     QLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWH
                     DNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDD
                     NTVQFVLTRPEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQY
                     QKDSRIRYKAFDGYWGTKPQIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARM
                     KQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSA
                     KNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRM
                     AEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSC
                     AASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTV
                     FEPVRKEVKGYVVDPLGKHHFENVSIE"
     gene            14888..15907
                     /gene="dppB"
                     /locus_tag="RHX21_001615"
     CDS             14888..15907
                     /gene="dppB"
                     /locus_tag="RHX21_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter permease DppB"
                     /protein_id="HDV1986817.1"
                     /translation="MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGI
                     SPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGISMKSRIPVWEEFVPRFQATLEL
                     GVCAMIFATAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHW
                     NLTPVSGRVSDMVFLDDSNPLTGFMLIDTAIWGEDGNFIDAVAHMILPAIVLGTIPLA
                     VIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLA
                     GAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPR
                     IRHKK"
     gene            15917..16819
                     /gene="dppC"
                     /locus_tag="RHX21_001616"
     CDS             15917..16819
                     /gene="dppC"
                     /locus_tag="RHX21_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010426221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter permease DppC"
                     /protein_id="HDV1986818.1"
                     /translation="MSQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVVIVLF
                     IAIFANWIAPYNPAEQFRDALLAPPAWQEGGSMAHLLGTDDVGRDVLSRLMYGARLSL
                     LVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS
                     IGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAP
                     LIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAI
                     LLTVLAFNLMGDGLRDALDPKLKQ"
     gene            16830..17813
                     /gene="dppD"
                     /locus_tag="RHX21_001617"
     CDS             16830..17813
                     /gene="dppD"
                     /locus_tag="RHX21_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HDV1986819.1"
                     /translation="MALLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGS
                     GKSVSSLAIMGLIDYPGRVMAEKLEFNGQDLQRISEKERRNLVGAEVAMIFQDPMTSL
                     NPCYTVGFQIMEAIKVHQGGNKSTRRQRAIDLLNQVGIPDPASRLDVYPHQLSGGMSQ
                     RVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVA
                     EAAHKIIVMYAGQVVETGDAHAIFHAPRHPYTQALLRALPEFAQDKERLASLPGVVPG
                     KYDRPNGCLLNPRCPYATDRCRAEEPALNMLADGRQSKCHYPLDDAGRPTL"
     gene            17810..18814
                     /gene="dppF"
                     /locus_tag="RHX21_001618"
     CDS             17810..18814
                     /gene="dppF"
                     /locus_tag="RHX21_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP binding subunit
                     DppF"
                     /protein_id="HDV1986820.1"
                     /translation="MSTQEATLQQPLLQAIDLKKHYPVKKGMFAPERLVKALDGVSFN
                     LERGKTLAVVGESGCGKSTLGRLLTMIETPTGGELYYQGQDLLKHDPQAQKLRRQKIQ
                     IVFQNPYGSLNPRKKVGQILEEPLLINTSLSKEQRREKALSMMAKVGLKTEHYDRYPH
                     MFSGGQRQRIAIARGLMLDPDVVIADEPVSALDVSVRAQVLNLMMDLQQELGLSYVFI
                     SHDLSVVEHIADEVMVMYLGRCVEKGTKDQIFNNPRHPYTQALLSATPRLNPDDRRER
                     IKLTGELPSPLNPPPGCAFNARCRRRFGPCTQLQPALKDYGGQLVACFAVDQDENPQR
                     "
     gene            complement(18844..20115)
                     /locus_tag="RHX21_001619"
     CDS             complement(18844..20115)
                     /locus_tag="RHX21_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HDV1986821.1"
                     /translation="MQHNTLSKHNQKLPFTRYDFGWVLLCIGMAIGAGTVLMPVQIGL
                     KGIWVFITAAIIAYPATWVVQDIYLKTLSESDSCNDYTDIISHYLGKNWGIFLGVIYF
                     LMIIHGIFIYSLSVVFDSASYLKTFGLTDADLSQSLLYKVAIFAVLVAIASGGERLLF
                     KISGPMVVVKVGIIVVFGFAMIPHWNFANITAFPQASVFFRDVLLTIPFCFFSAVFIQ
                     VLNPMNIAYRKREADKVLATRLALRTHRISYITLIAVILFFAFSFTFSISHEEAVSAF
                     EQNISALALAAQVIPGHIIHITSTVLNIFAVLTAFFGIYLGFHEAIKGIILNLLSRII
                     DTKKINSRMLTLAICAFIVITLTIWVSFRVSVLVFFQLGSPLYGIVSCLIPFFLIYKV
                     AQLEKLRGFKAWLILLYGILLCLSPLLKLIE"
     gene            20591..20698
                     /locus_tag="RHX21_001620"
     CDS             20591..20698
                     /locus_tag="RHX21_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin Ldr family
                     protein"
                     /protein_id="HDV1986822.1"
                     /translation="MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK"
     gene            complement(20785..22464)
                     /gene="bcsG"
                     /locus_tag="RHX21_001621"
                     /pseudo
     CDS             complement(20785..22464)
                     /gene="bcsG"
                     /locus_tag="RHX21_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312445.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsG"
     gene            complement(22461..22652)
                     /gene="bcsF"
                     /locus_tag="RHX21_001622"
     CDS             complement(22461..22652)
                     /gene="bcsF"
                     /locus_tag="RHX21_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417994.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsF"
                     /protein_id="HDV1986823.1"
                     /translation="MMTISDIIEIIVVCALIFFPLGYLARHSLRRIRDTLRLFFAKPR
                     YVKPAGTLRRTEKARATKK"
     gene            complement(22649..24220)
                     /gene="bcsE"
                     /locus_tag="RHX21_001623"
     CDS             complement(22649..24220)
                     /gene="bcsE"
                     /locus_tag="RHX21_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsE"
                     /protein_id="HDV1986824.1"
                     /translation="MRDIVDPVFSIGISSLWDELRHMPAGGVWWFNVDRHEDAISLAN
                     QTIASQAETAHVAVISMDSDPAKIFQLDDSQGPEKIKLFSMLNHEKGLYYLTRDLQCS
                     IDPHNYLFILVCANNAWQNIPAERLRSWLDKMNKWSRLNHCSLLVINPGNNNDKQFSL
                     LLEEYRSLFGLASLRFQGDQHLLDIAFWCNEKGVSARQQLSVQQQNGIWTLVQSEEAE
                     IQPRSDEKRILSNVAVLEGAPPLSEHWQLFNNNEVLFNEARTAQAATVVFSLQQNAQI
                     EPLARSIHTLRRQRGSAMKILVRENTASLRATDERLLLACGANMVIPWNAPLSRCLTM
                     IESVQGQKFSRYVPEDITTLLSMTQPLKLRGFQKWDVFCNAVNNMMNNPLLPAHGKGV
                     LVALRPVPGIRVEQALTLCRPNRTGDIMTIGGNRLVLFLSFCRINDLDTALNHIFPLP
                     TGDIFSNRMVWFEDDQISAELVQMRLLAPEQWGMPLPLTQSSKPVINAEHDGRHWRRI
                     PEPMRLLDDAVERSS"
     gene            24493..24681
                     /locus_tag="RHX21_001624"
     CDS             24493..24681
                     /locus_tag="RHX21_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhjR family protein"
                     /protein_id="HDV1986825.1"
                     /translation="MNNNEPDTLPDPAIGYIFQNDIVALKQAFSLPDIDYADISQREQ
                     LAAALKRWPLLAEFAQQK"
     gene            24693..25436
                     /gene="bcsQ"
                     /locus_tag="RHX21_001625"
     CDS             24693..25436
                     /gene="bcsQ"
                     /locus_tag="RHX21_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsQ"
                     /protein_id="HDV1986826.1"
                     /translation="MAVLGLRGGVGTTTITAALAWSLQMLGENVLVVDACPDNLLRLS
                     FNVDFTHRQGWARAMLDGQDWRDAGLRYTSQLDLLPFGQLSIEEQENPQHWQTRLSDI
                     CSGLQQLKASGRYQWILIDLPRDASQITHQLLSLCDHSLAIVNVDANCHIRLHQQALP
                     DGAHILINDFRIGSQVQDDIYQLWLQSQRRLLPMLIHRDEAMAECLAAKQPVGEYRSD
                     ALAAEEILTLANWCLLNYSGLKTPVGSAS"
     gene            25433..28051
                     /gene="bcsA"
                     /locus_tag="RHX21_001626"
     CDS             25433..28051
                     /gene="bcsA"
                     /locus_tag="RHX21_001626"
                     /EC_number="2.4.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417990.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-forming cellulose synthase catalytic
                     subunit"
                     /protein_id="HDV1986827.1"
                     /translation="MSILTRWLLIPPVNARLIGRYRDYRRHGASAFSATLGCFWMILA
                     WIFIPLEHPRWQRIRAEHKNLYPHINASRPRPLDPVRYLIQTCWLLIGTSRKETPKPR
                     RRAFSGLQNIRGRYHQWMNELPERVSHKTQHLDEKKELGHLSAGARRLILGIIVTFSL
                     ILALICVTQPFNPLAQFIFLMLLWGVALIVRRMPGRFSALMLIVLSLTVSCRYIWWRY
                     TSTLNWDDPVSLVCGLILLFAETYAWIVLVLGYFQVVWPLNRQPVPLPKDMSLWPSVD
                     IFVPTYNEDLNVVKNTIYASLGIDWPKDKLNIWILDDGGREEFRQFAQNVGVKYIART
                     THEHAKAGNINNALKYAKGEFVSIFDCDHVPTRSFLQMTMGWFLKEKQLAMMQTPHHF
                     FSPDPFERNLGRFRKTPNEGTLFYGLVQDGNDMWDATFFCGSCAVIRRKPLDEIGGIA
                     VETVTEDAHTSLRLHRRGYTSAYMRIPQAAGLATESLSAHIGQRIRWARGMVQIFRLD
                     NPLTGKGLKFAQRLCYVNAMFHFLSGIPRLIFLTAPLAFLLLHAYIIYAPALMIALFV
                     LPHMIHASLTNSKIQGKYRHSFWSEIYETVLAWYIAPPTLVALINPHKGKFNVTAKGG
                     LVEEEYVDWVISRPYIFLVLLNLVGVAVGIWRYFYGPPTEMLTVVVSMVWVFYNLIVL
                     GGAVAVSVESKQVRRSHRVEMTMPAAIAREDGHLFSCTVQDFSDGGLGIKINGQAQIL
                     EGQKVNLLLKRGQQEYVFPTQVARVMGNEVGLKLMPLTTQQHIDFVQCTFARADTWAL
                     WQDSYPEDKPLESLLDILKLGFRGYRHLAEFAPSSVKGIFRVLTSLVSWVVSFIPRRP
                     ERSETAQPSDQALAQQ"
     gene            28062..30401
                     /gene="bcsB"
                     /locus_tag="RHX21_001627"
     CDS             28062..30401
                     /gene="bcsB"
                     /locus_tag="RHX21_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HDV1986828.1"
                     /translation="MKRKLFWICAVAMGMSAFPSFMTQATPATQPLINAEPAVAAQTE
                     QNPQVGQVMPGVQGADAPVVAQNGPSRDVKLTFAQIAPPPGSMVLRGINPNGSIEFGM
                     RSDEVVTKAMLNLEYTPSPSLLPVQSQLKVYLNDELMGVLPVTKEQLGKKTLAQMPIN
                     PLFITDFNRVRLEFVGHYQDVCENPASTTLWLDVGRSSGLDLTYQTLNVKNDLSHFPV
                     PFFDPRDNRTNTLPMVFAGAPDVGLQQASAIVASWFGSRSGWRGQNFPVLYNQLPDRN
                     AIVFATNDKRPDFLRDHPAVKAPVIEMINHPQNPYVKLLVVFGRDDKDLLQAAKGIAQ
                     GNILFRGESVVVNEVKPLLPRKPYDAPNWVRTDRPVTFGELKTYEEQLQSSGLEPAAI
                     NVSLNLPPDLYLMRSTGIDMDINYRYTMPPVKDSSRMDISLNNQFLQSFNLSSKQEAN
                     RLLLRIPVLQGLLDGKTDVSIPALKLGATNQLRFDFEYMNPMPGGSVDNCITFQPVQN
                     HVVIGDDSTIDFSKYYHFIPMPDLRAFANAGFPFSRMADLSQTITVMPKAPNEAQMET
                     LLNTVGFIGAQTGFPAINLTVTDDGSTIQGKDADIMIIGGIPDKLKDDKQIDLLVQAT
                     ESWVKTPMRQTPFPGIVPDESDRAAETQSTLTSSGAMAAVIGFQSPYNDQRSVIALLA
                     DSPRGYEMLNDAVNDSGKRATMFGSVAVIRESGINSLRVGDVYYVGHLPWFERLWYAL
                     ANHPILLAVLAAISVILLAWVLWRLLRIISRRRLNPDNE"
     gene            30408..31514
                     /gene="bcsZ"
                     /locus_tag="RHX21_001628"
     CDS             30408..31514
                     /gene="bcsZ"
                     /locus_tag="RHX21_001628"
                     /EC_number="3.2.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase"
                     /protein_id="HDV1986829.1"
                     /translation="MNVLRSGIVTMLLLAAFSVQAACTWPAWEQFKKDYISQEGRVID
                     PSDARKITTSEGQSYGMFFALAANDRVAFDNILDWTQNNLAQGSLKERLPAWLWGKKE
                     NSKWEVLDSNSASDGDVWMAWSLLEAGRLWKEQRYTDIGSALLKRIAREEVVTVPGLG
                     SMLLPGKVGFAEDNSWRFNPSYLPPTLAQYFTRFGAPWTTLRETNQRLLLETAPKGFS
                     PDWVRYEKDKGWQLKAEKTLISSYDAIRVYMWVGMMPDSDPQKARMLNRFKPMATFTE
                     KNGYPPEKVDVATGKAQGKGPVGFSAAMLPFLQNRDAQAVQRQRVADNFPGSDAYYNY
                     VLTLFGQGWDQHRFRFSTKGELLPDWGQECANSH"
     gene            31496..34969
                     /gene="bcsC"
                     /locus_tag="RHX21_001629"
     CDS             31496..34969
                     /gene="bcsC"
                     /locus_tag="RHX21_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026226.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsC"
                     /protein_id="HDV1986830.1"
                     /translation="MRKFTLNIFTLSLGLAVMPMVEAAPTAQQQLLEQVRLGEATHRE
                     DLVQQSLYRLELIDPNNPDVVAARFRSLLRQGDIDGAQKQLDRLSQLAPSSNAYKSSR
                     TTMLLSTPDGRQALQQARLQATTGHAEEAVASYNKLFNGAPPEGDIAVEYWSTVAKIP
                     ARRGEAINQLKRINADAPGNTGLQNNLALLLFSSDRRDEGFAVLEQMAKSNAGREGAS
                     KIWYGQIKDMPVSDASVSALKKYLSIFSDGDSVAAAQSQLAEQQKQLADPAFRARAQG
                     LAAVDSGMAGKAIPELQQAVRANPKDSEALGALGQAYSQKGDRANAVANLEKALALDP
                     HSSNNDKWNSLLKVNRYWLAIQQGDAALKANNPDRAERLFQQARNVDNTDSYAVLGLG
                     DVAMARKDYPAAERYYQQTLRMDSGNTNAVRGLANIYRQQSPEKAEAFIASLSASQRR
                     SIDDIERSLQNDRLAQQAEALENQGKWAQAAALQRQRLALDPGSVWITYRLSQDLWQA
                     GQRSQADTLMRNLAQQKPNDPEQVYAYGLYLSGHDHDRAALAHINSLPRAQWNSNIQE
                     LVNRLQSDQVLETANRLRESGKEAEAEAMLRQQPPSTRIDLTLADWAQQRRDYTAARA
                     AYQNVLTREPTNADAILGLTEVDIAAGDTAAARSQLAKLPATDNASLNTQRRVALAQA
                     QLGDTAAAQQTFNKLIPQAKSQPPSMESAMVLRDGAKFEAQAGDPKQALETYKDAMVA
                     SGVTTTRPQDNDTFTRLTRNDEKDDWLKRGVRSDAADLYRQQDLNVTLEHDYWGSSGT
                     GGYSDLKAHTTMLQVDAPYSDGRMFFRSDFVNMNVGSFSTNADGKWDDNWGTCTLQDC
                     SGNRSQSDSGASVAVGWRNDVWSWDIGTTPMGFNVVDVVGGISYSDDIGPLGYTVNAH
                     RRPISSSLLAFGGQKDSPSNTGKKWGGVRADGVGLSLSYDKGEANGVWASLSGDQLTG
                     KNVEDNWRVRWMTGYYYKVINQNNRRVTIGLNNMIWHYDKDLSGYSLGQGGYYSPQEY
                     LSFAIPVMWRERTENWSWELGASGSWSHSRTKTMPRYPLMNLIPTDWQEEAARQSNDG
                     GSSQGFGYTARALLERRVTSNWFVGTAIDIQQAKDYAPSHFLLYVRYSAAGWQGDMDL
                     PPQPLIPYADW"
     gene            35051..37039
                     /gene="hmsP"
                     /locus_tag="RHX21_001630"
     CDS             35051..37039
                     /gene="hmsP"
                     /locus_tag="RHX21_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417986.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator HmsP"
                     /protein_id="HDV1986831.1"
                     /translation="MRVSRSLTIKQMAMVAAVVLVFVFIFCTVLLFHLVQQNRYNTAT
                     QLESIARSVREPLSSAILKGDIPEAEAILASIKPAGVVSRADVVLPNQFQALRKSFIP
                     ERPVPVMVTRLFELPVQISLGVYSLERPANPQPIAYLVLQADSFRMYKFVMSTLSTLV
                     TIYLLLSLILTVAISWCINRLILHPLRNIARELNAIPAQELVGHQLALPRLHQDDEIG
                     MLVRSYNLNQQLLQRHYEEQNENAMRFPVSDLPNKALLMEMLEQVVARKQTTALMIIT
                     CETLRDTAGVLKEAQREILLLTLVEKLKSVLSPRMILAQISGYDFAVIANGVQEPWHA
                     ITLGQQVLTIMSERLPIERIQLRPHCSIGVAMFYGDLTAEQLYSRAISAAFTARHKGK
                     NQIQFFDPQQMEAAQKRLTEESDILNALENHQFAIWLQPQVEMTSGKLVSAEVLLRIQ
                     QPDGSWDLPDGLIDRIECCGLMVTVGHWVLEESCRLLAAWQERGIMLPLSVNLSALQL
                     MHPNMVADMLELLTRYRIQPGTLILEVTESRRIDDPHAAVAILRPLRNAGVRVALDDF
                     GMGYAGLRQLQHMKSLPIDVLKIDKMFVEGLPEDSSMIAAIIMLAQSLNLQMIAEGVE
                     TEAQRDWLAKAGVGIAQGFLFARPLPIEIFEESYLEEK"
     gene            37222..38508
                     /gene="dctA"
                     /locus_tag="RHX21_001631"
     CDS             37222..38508
                     /gene="dctA"
                     /locus_tag="RHX21_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylate transporter DctC"
                     /protein_id="HDV1986832.1"
                     /translation="MKTSLFKSLYFQVLTAIAIGILLGHFYPEIGEQMKPLGDGFVKL
                     IKMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEIVSTIALIIGLIIVNVVQPG
                     AGMNVDPATLDAKAVAVYADQAKDQGIVAFIMDVIPASVIGAFASGNILQVLLFAVLF
                     GFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGTLVQ
                     LGQLIICFYITCILFVVLVLGSIAKATGFSIFKFIRYIREELLIVLGTSSSESALPRM
                     LDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSQMDIVHQITLLI
                     VLLLSSKGAAGVTGSGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLVGNG
                     VATIVVAKWVKELDHKKLDDVLNNRAPDGKTHELSS"
     gene            38729..40225
                     /locus_tag="RHX21_001632"
     CDS             38729..40225
                     /locus_tag="RHX21_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDV1986833.1"
                     /translation="MQGTKIRLLAGGLLMMATAGYVQADALQPDPAWQQGTLSNGLQW
                     QVLTTPQRPSDRVEIRLLVNTGSLAESTQQSGYSHAIPRIALTQSGGLDAAQARSLWQ
                     QGIDPKRPMPPVIVSYDTTLFNLSLPNNRNDLLKEALSYLANATGKLTITPETINHAL
                     QSQDMVATWPADTKEGWWRYRLKGSTLLGHDPADPLKQPVEAEKIKDFYQKWYTPDAM
                     TLLVVGNVDARSVVDQINKTFGELKGKRETPAPVPTLSPLRAEAVSIMTDAVRQDRLS
                     IMWDTPWQPIRESAALLRYWRADLAREALFWHVQQALSASNSKDIGLGFDCRVLYLRA
                     QCAINIESPNDKLNSNLNLVARELAKVRDKGLPEEEFNALVAQKKLELQKLFAAYARA
                     DTDILMGQRMRSLQNQVVDIAPEQYQKLRQDFLNSLTVEMLNQDLRQQLSNDMALILL
                     QPKGEPEFNMKALQAAWDQIMAPSTAAATTSVATDDVHPEVTDIPPAQ"
     gene            complement(40321..41250)
                     /gene="kdgK"
                     /locus_tag="RHX21_001633"
     CDS             complement(40321..41250)
                     /gene="kdgK"
                     /locus_tag="RHX21_001633"
                     /EC_number="2.7.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417983.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxygluconokinase"
                     /protein_id="HDV1986834.1"
                     /translation="MSKKIAVIGECMIELSEKGADVKRGFGGDTLNTSVYIARQVDPA
                     ALTVHYVTALGTDSFSQQMLDAWHGENVDTSLTQRMENRLPGLYYIETDSTGERTFYY
                     WRNEAAAKFWLESEQSAAICEELANFDYLYLSGISLAILSPTSREKLLSLLRECRANG
                     GKVIFDNNYRPRLWASKEETQQVYQQMLECTDIAFLTLDDEDALWGQQPVEDVIARTH
                     NAGVKEVVVKRGADSCLVSIAGEGLVDVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLT
                     GGSAENAAKRGHLTASTVIQYRGAIIPREAMPA"
     gene            41482..42249
                     /gene="pdeH"
                     /locus_tag="RHX21_001634"
     CDS             41482..42249
                     /gene="pdeH"
                     /locus_tag="RHX21_001634"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417982.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase"
                     /protein_id="HDV1986835.1"
                     /translation="MIRQVIQRISNPEASIESLQERRFWLQCERAYTWQPIYQTCGRL
                     MAVELLTVVTHPLNPSQRLPPDRYFTEITVSHRMEVVKEQIDLLAQKADFFIEHGLLA
                     SVNIDGPTLIALRQQPKILRQIERLPWLRFELVEHIRLPKDSTFASMCEFGPLWLDDF
                     GTGMANFSALSEVRYDYIKIARELFVMLRQSPEGRTLFSQLLHLMNRYCRGVIVEGVE
                     TPEEWRDVQNSPAFAAQGWFLSRPAPIETLNTAVLAL"
     gene            42319..>42668
                     /locus_tag="RHX21_001635"
     CDS             42319..>42668
                     /locus_tag="RHX21_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417981.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HDV1986836.1"
                     /translation="MSKAGKITAAISVAFLLLIVVAIILIATFDWNRLKPTINQKVSA
                     ELNRPFAIRGDLGVVWERQKQETGWRSWVPWPHVHAEDIILGNPPDIPEVTMVHLPRV
                     EATLAPLALLTKTV"
BASE COUNT        10041 a        10816 c        11537 g        10274 t
ORIGIN      
        1 agtgaggcta ccctatgcct gaacaccata aggttagcct cttactcgtt ggaaatcaac
       61 acagggggct gggaatgccg cagaaatata gattactttc tttaatagtg atttgtttca
      121 cgcttttatt tttcacctgg atgataagag attcactgtg tgaattgcat attaaacagg
      181 ggtgttatga gctggcggca tttttagcct gcaatttaaa agagtaagag tcttcggcgg
      241 gaagttattc ccgcctttct tacggcgttg cgcattctca ttgcacccaa atttattttt
      301 cacaaaaata atactagatt ttattacgcg atcgattatt tatttcctga aaaacaaata
      361 aaaaaatccc cgccaaatgg cagggatctt agattctgtg cttttaagca gagattacag
      421 gctggttacg ttaccagctg ccgggccttt agcgccgctt tcgatggtga aggacacttt
      481 ctgaccttcg tccagagatt tgtaaccatc gttctggata gcagagaagt gtacgaacac
      541 gtctttagag ccatcgtcag gagtgatgaa gccgaagcct ttgtcagcgt tgaaccattt
      601 tacgatacca gtcattttac cggacatagt gtattacctt taataattaa gtgtgccttt
      661 cggcgatatg gcgtgcttta cagattttga agcgttaaag gaatgtgcac tacgaggggt
      721 atcaacgata actcttgaag ggacttgcct tactacactg ctttaatggt ctgtacgtca
      781 aaccgttgat gtgcattaag ccacgcattg gcgggtgatg caacaattat ttttcatatt
      841 tatgattaat cggttggaaa acggtcctgt catcaggacc gtaaacagca ataaagtgga
      901 taaaagtcta ttccatcaac tgcttactta atgccgggtt ggcttgaatc aaacgcatca
      961 attttagttc ggcacttgaa ggcttcacgc gtctggattc ccattccttt accatggcga
     1021 ctgatacgcc caaaacccgg gcgaaatcat cgatttttaa tcctgtccct tttcgtaact
     1081 gctcaatttc ggtacaggac gttgttctgt gcgtcagggt aattttctgc gtttcatctt
     1141 taaaaacaat ctgttccagg ctgctcaaca gctcatgcat tggatcttta tattccattg
     1201 aaaactcctc aaatcacact gcgggatcgt gaattgcatc gaagctcatt aagaatagtc
     1261 gggaaaagca gacacagcgg ggtgaagtca gggcatgctc tggctatgat tcgattcagc
     1321 cagtcattta gcgtgactta tagccaccta acgatctgat aaatgccgat atatctctta
     1381 ccactcctgg tttgtaaaga tttcgaaaat ctaaccttct gcgaaggcgt aaatctctgg
     1441 ctacaaaaaa agcaacggca ctatcatttt ttaacaatga aacaacaaat taaccttgtt
     1501 tcattttctc catgatttta ccaggaagat tacgtagaaa gggtatcctg caagcctgtc
     1561 ctggactatc cttgtcacgt cagacacgcg tgtgtcgttg tgcgcttttt ttgggtgaaa
     1621 ggagtaagaa aatggcgaca ggaaagtcct gctctcgctg gtttgcgcct cttgcggcgt
     1681 tattaatggt agttagcctg agtgggtgtt ttgataaaga aggcgatcag cgtaaagcgt
     1741 ttatcgactt cctgcagaat acagtgatgc gtagcggtga acgtctacca accctgactg
     1801 ccgatcagaa aaaacagttt ggtccttttg tctctgatta cgcgattctg tatggttatt
     1861 ctcagcaggt gaatcaggcg atggattccg gtctgcgccc ggtcgtagac agcgttaacg
     1921 caattcgcgt accgcaggat tacgttacgc aaagcggtcc gctgcgtgaa atgaacggtt
     1981 cgctgggtgt gctggcgcaa caactgcaaa atgcgaagtt gcaggccgat gctgcgcact
     2041 ctgcgctaaa acagaccgat gatttgaaac cggtctttga tcaggcattc accaaagtgg
     2101 taacgacgcc agctgatgca ttgcaaccgt tgattccggc tgcacaaact ttcacgcaac
     2161 aactggtgat ggttggagac tacattgctc agcaaggtac tcaggtgagc tttgtcgcaa
     2221 atggcatcca gttcccgact tcacagcagg caagtgaata taacaaactg attgcgccat
     2281 taccggcaca acatcaggcg tttaatcagg cctggactac agcagttact gcaacccaat
     2341 aaagagtaaa agcccgagcg attatcgggc tttacttcac gcagtcgcgg cttagtccgc
     2401 gacgtgcgga ttcacacagt tcttctcaac ctttccttgt aacgcatcaa tcaaattatc
     2461 cacggcacag gcggccatgc cataacgcgt ctcatgggtg gcagatccaa tatgcggtac
     2521 tgcgacgacg ttggccattg agagcaacgg cgaatctacg gacagtggct cttgttcgaa
     2581 gacatccagc ccggcggcgt gaatttcgcc tttctgcaat gcagcaatca gtgcattttc
     2641 atcaaccacc gggccacgtc cggcattaat gaaaatggcg gaggatttca ttttggcgaa
     2701 ttgttctgcg ccaaacagat gatgcgtctc atcagttaac ggcaggatca ggcaaacgaa
     2761 atctgactct tgtaacagag tatccaaatc gcagtagcgg gcgttgaagc gttcttctgc
     2821 ttctttatgg tggcggcgcg cgttatagag gatgggcatg ttgaagccaa agtgcgcacg
     2881 ttgtgccagc gccataccga tccgtcccat cccgacaatg cccagtgttt tatggtgaac
     2941 gtcagtgccg taccagtccg ggcctatgct cgcggtccat tcgcctgctt ttacccgttc
     3001 tgctacctcc acaacccgac gagcggtaga caacaccagc gccatcagcg tatcggcgac
     3061 ggtttctgtt aatacggttg gcgtgtgcat cagcagaatt tttcgggcgg taagcgcatc
     3121 gacatcaaaa ttgtcatagc cgacggagat cgttgatgtg gcacgcagtt tcggcatttt
     3181 ttccagcaat gcggcatcaa cattctcgtt tgaacccagt aaaccttcag cttcggcaaa
     3241 aattgctgca ttttgttcga cggtttgtgg gctgaggttt gccacctggt gaacggtgaa
     3301 atgctcttgc aggcgttgca gtaaatcatc aggtaaggct ttgtagagga taacggacgg
     3361 cttcatgctt ctctccattc actgataagg cgatcacctt agcctgaaat atgatgaagg
     3421 aaaactgaag aatgccaggt gatttctgca tcacctggca tgaaagggat tacagcgggc
     3481 ttaaggtaat ttctacacgg cggttttgcg ccttaccttc tgcggtgctg ttgctggcga
     3541 ttgggttagc cgggccaagg ccctgagtac ggatgcggct ggcgtccacg ccctgggtga
     3601 tcaacgcgct ggcaacggaa tccgcacgtt gctgggagag acgcatgttc aggtcgtgac
     3661 cacccgtgct gtcggtataa ccaatcacgt taaccgccgt tttcggatac tctttcagca
     3721 ccattgccac gccggtcagg gtgttagcgc ccgcaggttt cagggtcgcg ctgctgctgt
     3781 cgaaggtcac attgttcggc atattgagga taatgttatc cccgctgcgg gttacgctaa
     3841 caccagtgcc gcgcattttg tcacgcagct tcgcttcctg cacatccatg taataaccca
     3901 cgccgccgcc cagagctgcg cctgctgctg cgccaatcag cgcgccttta ccgcgatctt
     3961 tcttcgaaga agagagcgca ccaatacccg cgcccacgag agagcccaga cctgcgccga
     4021 tagcagattt acctgcttcg cgttcgccgg tgtaagggtt agttgtgcag ccagataccg
     4081 ccagagcgcc actcactacg gcggcaataa gataaacacg tttcttcatt gttaatcctt
     4141 aataaccttt ttattctttg ccacgggttc cgtggcggga gattatgccg cgtgaacatg
     4201 aagattattc ctgggaatac tcggaaattt gtaagtaata tttaactgct caatacatct
     4261 aacctttcag gagttttcgg tttggccaac tcatcctcac gatattccgt tctgactgcc
     4321 gcccattggg ggcccatgct ggttgaaacc gacggcgaaa ccgtgtttag ctcgcatggc
     4381 gcgttagcca caggaatgga aaactccttg cagagcgcgg ttcgcgacca ggttcacagc
     4441 aatacacggg tacgatttcc aatggtgcgc aaaggctttc tcgcgtcacc ggaaaacccg
     4501 caaggcattc gtgggcagga tgaatttgtt cgcgtgagtt gggatgaggc gctggatctt
     4561 attcaccaac aacataaacg cattcgtgag gcttatggtc cggcatcgat ttttgctggt
     4621 tcctacggct ggcgttcaaa cggcgtgctg cataaggcct cgacattatt acaacgctat
     4681 atggcgctgg caggcggtta tatcgggcat ctgggggatt attcgaccgg tgcggcacag
     4741 gcgatcatgc cgtatgtcgt gggtggcagc gaagtttatc aacagcaaac cagttggccg
     4801 ctggtgctgg aacatagcga tgtcgtggtg ttgtggagtg ctaacccact caatacgctg
     4861 aaaattgcgt ggaatgcatc tgatgagcag gggctttctt acttttccgc actgcgtgac
     4921 agcgggaaaa agctgatctg tattgatcca atgcgatcgg aaaccgtcga tttctttggc
     4981 gataaaatgg agtgggtggc accgcacatg ggcaccgatg ttgcgctgat gctggggatc
     5041 gcccatacgc tggtggaaaa tggttggcac gacgaagcgt ttctgacgcg ttgcaccaca
     5101 ggttatgccg tcttcgcctc ttatttgctg ggcgagagtg acggaatagc gaaaaacgcc
     5161 gaatgggcgg cagagatttg tggggttaac gcagcgaaaa tccgcgagct ggcggctctt
     5221 ttccaccaaa acacgaccat gctgatggct ggctggggaa tgcagcgcca acagtttggt
     5281 gagcaaaaac actggatgat cgtcacgctg gcggcaatgt tggggcaaat cggcacaccc
     5341 ggcggcggtt ttggtctttc ttatcatttt gccaatggtg gtaaccccac gcggcgttct
     5401 gcggtgctct cttccatgca gggcagcttg ccgggtggct gcgatgcggt ggataaaatc
     5461 cctgttgccc gcattgttga agcactggaa aaccctggtg gcgcatatca acacaacggt
     5521 atgaaccgac atttcccgga tattcgtttt atctggtggg cgggcggtgc caactttact
     5581 catcatcagg ataccaatcg tctgatccgt gcctggcaaa aaccggagct ggtggtgatc
     5641 tctgaatgct tctggacggc ggcggcgaaa cacgcggata tcgttctgcc tgcgactacc
     5701 tcttttgagc gtaatgatct caccatgacc ggtgattaca gtaatcagca tctggtgccg
     5761 atgaagcaag tggtgccgcc acgctatgaa gcgcgtaatg attttgatgt ttttgccgag
     5821 ttgagtgaac gttgggagaa gggcggctat gcgcggttta cggaaggaaa aagtcagctg
     5881 caatggctgg aaacgtttta taacgttgcc cggcagcgcg gggcaagcca gcaggttgaa
     5941 ttgccgccat ttgctgagtt ctggcaagcc aaccagttaa ttgagatgcc ggaaaacccg
     6001 gacagcgagc ggtttattcg cttcgctgat ttttgccgcg atccgctggc gcatccgtta
     6061 aaaaccgcca gcggcaagat tgaaatcttc tcacagcgta ttgccgatta cggttacccg
     6121 gattgccctg ggcatccaat gtggctggag ccggacgaat ggcagggcaa tgccgaacca
     6181 gaacagttgc aggtactttc tgcccatccg gcgcaccgcc tgcacagcca gctgaattac
     6241 agttctctgc gcgaattgta cgcggtagca aaccgtgagc ctgtcaccat tcatcctgac
     6301 gatgctcagg cgcgcggcat aaccgaaggg gatatggtgc gggtgtggaa ctcccgtggg
     6361 cagatccttg ccggagcggt cattagcgag ggaattaaac ctggcgtgat ttgcattcac
     6421 gaaggggcat ggccggatct ggatttaacc gctgacggta tttgtaaaaa cggcgcagtg
     6481 aacgtgctga ccaaagatct ccccagctcg cggctgggga atggctgtgc gggtaatacg
     6541 gcgctggcat ggctggaaaa atacaacggt ccggaactga cacttacagc gtttgaacca
     6601 ccggccagct cataatccag gtgggtagtt gggtttcatc ctgccatgcg caatcgacaa
     6661 tgtgaaaacc ctgcgcacgg taaaaatcta tcgccggttg atttttttga taaacctcca
     6721 gcatcagatg gggatagcgc tgctgcacat actgcatcag cgccttacca ataccgcgtc
     6781 tgacggcctt cggtgcgaca aacattgctg ccagaaatcg gccttccata atgctgacaa
     6841 aaccgagaag cttaccgtcc tcttcccaga cccagttttg cgcgttggca agataggcat
     6901 cccgcaccag cggaatgcag tcacgccagt aattcgcttt tataaaggga tgcccccagg
     6961 ttgtactttc cagccacagt tcgaggatcg cggggagttc tgaacgttgc gcttcccgaa
     7021 tcatggttta tttcccggat agcaacagca gccaaccaca tgatcattca ccagcccaca
     7081 tgcctgcata aaggagtaac agattgtggt gccgacaaac ttaaaaccac gttttttcag
     7141 tgccttagat agggcgtcgg aggcggacgt agatgtggga atttcgctca acgttgtggc
     7201 ttgtgtcacc tgtggctgat gatttacaaa cgaccagaca aagtcggcaa acggttcgcc
     7261 gttctgttcc atttgcaggt acgcccgcgc attaccaata attgcctgaa ttttccctcg
     7321 atggcggata atcccggcgt cctgtaccag tctttcgaca tcctcttcct gcattgctgc
     7381 gaccttcacc ggatcgaact gatgaaagca ggcgcgatag ttttcgcgtt ttttgaggac
     7441 ggtgatccac gataacccag cctgctgccc ttcaaggcag atcatttcga acagtttttt
     7501 actgtcagtt tcaggcacgc cccattcatt atcatggtag gcaatataaa gcgggtcctg
     7561 actcacccag ccgcaacgtt ccatactttc cctcgctatg tacccgatcg taaaaatttc
     7621 agccgctttt cttgacgcat cggtgaaaaa gtcaatattt aatacagggc tactatgccc
     7681 gatatccttc atacaatgac aataatattg ccgaattcgg ctcttccctg gagtcgtgtt
     7741 aatgatcata aaaaaaagcg gtggtcgctg gcagctaagc ctgctggcga gcgtggtaat
     7801 cagtgccttt tttctcaaca cagcttacgc ctggcaacaa gaatatatcg ttgatacgca
     7861 acccggacat tccacagagc gttacacctg ggatagtgat catcaacctg attacaacga
     7921 tattttgtcg caacgtattc aaagtagcca aagggcgctg ggactggaag tcaatctggc
     7981 ggaagaaact cctgtggatg tgaccagcag tatgagtatg ggctggaatt ttcctttata
     8041 tgaacaggtt acaaccggcc cggtcgcggc attacattac gatggcacaa ccacctcgat
     8101 gtataacgag tttggcgaca gtactaccac gctgaccgat ccgttatggc atgccagcgt
     8161 gagtagctta ggctggcgtg ttgactcccg gcttggcgat ctccgaccct gggcgcaaat
     8221 cagctataac cagcaatttg gcgagaatat ctggaaggcg caatcaggcc tgagccggat
     8281 gacggcgaca aaccagaacg gcaactggct ggatgtcacc gtaggcgctg atatgttgct
     8341 caatcaaaat attgccgcct atgccgcgct aactcaggca gaaaatacca ctaataatag
     8401 cgactatctg tatacgatgg gggttagcgc cagattttaa cgtaacagtc acaattgaaa
     8461 ccattgaata acaacagttg tggcgatagt gggtgctaac ttaccaaata ataaatttgg
     8521 tgaataattg tcgcgtcatt cattcctgaa ctaaggcatt tcattccgtt ctgatggcat
     8581 ttcatgccgt ttttccccag gcataaagtg cacttcgtta tggttgtcgg cagagatttt
     8641 tcctttttat tactgcagga atactgccat gacaccttca aattatcagc gtacccgctg
     8701 gctgacactc atcggtacaa tcattaccca gtttgcgctg gggtcggttt atacctggag
     8761 cctgtttaat ggcgcgcttt ccgccaagct ggatgcgccg gtaagccagg tcgctttctc
     8821 tttcggcttg ttaagtctgg ggctggcaat ttcatcttct gttgcgggca aattacagga
     8881 acgttttggc gttaaacgcg tcaccatggc ttccggcatt ttgctgggat taggcttctt
     8941 cctgaccgcg cattctgaca acctgatgat gctgtggtta agcgccggtg tgctggtcgg
     9001 tctggcggat ggcgcgggtt acctgctgac gctctctaac tgcgtgaagt ggttcccgga
     9061 gcgtaaaggt ctgatatccg cgttcgctat cggttcttat ggtctgggta gcctgggttt
     9121 caaatttatc gacacgcggc tgctggaaac ggtgggtctg gaaaaaacct ttgtgatttg
     9181 gggagcgatt gcgctggtga tgattgtttt cggcgcaacg ttaatgaaag acgcaccaaa
     9241 acaggaagtg aaaaccagca atggtgtggt ggagaaagat tacacgctgg cagagtcgat
     9301 gcgtaaaccg cagtactgga tgttagcggt aatgttcctg actgcctgca tgagcggcct
     9361 gtacgtgatt ggggtagcga aagatatcgc ccaaagtctg gcacaccttg atgtggtttc
     9421 cgcagctaat gcagtcactg ttatttccat cgccaacctt tcaggtcgtc tggttctggg
     9481 gatactgtct gacaaaatcg cccgtatccg tgttatcacc attggtcagg tgatttcgct
     9541 agtgggtatg gcggccctgc tgtttgcacc actgaatgca gtgacgttct ttgcagcgat
     9601 tgcctgcgtg gcatttaact ttggcggcac tattaccgtc tttccgtcac tggtcagtga
     9661 gttcttcggc ctcaataacc tggcgaaaaa ctacggtgtg atttacctcg gtttcggtat
     9721 cggtagcatt tttggttcga ttatcgcctc actgtttggc ggtttctatg tgaccttcta
     9781 cgtgattttc gccctgctga ttctgtcatt ggcgctttct acgacgattc gtcagccaga
     9841 gcagaaaatg ttgcgtgagg cgcatggctc cctttaatgc tcagccgcga gctactgggc
     9901 ttcagcttcc gtgtgcatca aacgcatcaa cgaaatgtat aaacaatgac tcgtaaaatt
     9961 tgggccagtt aactggccct ttttactgct ttttgtaacg ctaaagtctc ttttcaaact
    10021 tgcatttttg taaatttgtg cttcatgcac actctttccc cacacttttt cgctttgctg
    10081 tggtctactt attcgcgcgt gtagatttta cttatctgac tacctccgca cttttcccct
    10141 gccgggcctg aaaagccgct aagcagggtg ttatcacctg tttgtccagg gtttgtttgc
    10201 atgagataca tcaaatcgat tacacagcag aagctgagct ttttgcttgc aatctatatt
    10261 ggccttttta tgaatggcgc ggttttttat cgccgcttcg gcagctatgc gcacgatttt
    10321 accgtctgga aaggcgtttc tgctgttgtt gaactggccg ccaccgtact ggtgaccttc
    10381 tttttactac gtcttctatc gctgtttggc cgccgcagct ggcgtattct ggcgtcgctg
    10441 gtggtgctct tttccgcagg tgccagctat tacatgacct tccttaatgt ggtcattggt
    10501 tatggcatca tcgcttccgt catgaccacc gatatcgacc tgtcaaaaga agttgttggt
    10561 ctgaacttta ttctctggtt aatcgccgtt agtgcattgc ctcttatcct tatctggaat
    10621 aaccgctgtc gctacacctt gctccgacaa ctgcgaaccc cagggcagcg tattcgcagc
    10681 ctggcggtcg tcgtactggc gggtattatg gtttgggcac cgattcgttt gctggatatc
    10741 cagcagaaga aagtggagag ggcgaccggc gttgatttgc cgagttatgg cggtgtcgta
    10801 gcgaactctt atctgccatc aaactggctt tctgcgttgg ggctgtatgc ctgggcgcgg
    10861 gtcgatgaat cttccgataa taattcattg cttaatccgg cgaagaaatt cacttatcag
    10921 gcaccgcaaa acgttgatga cacttatgtc gtgtttatca tcggtgaaac cacgcgttgg
    10981 gaccatatgg gcattttcgg ctatgagcgt aataccacgc cgaaactggc ccaggagaaa
    11041 aatctggcgg cgttccgtgg ttactcctgt gataccgcaa ccaaactctc actgcgttgc
    11101 atgtttgtac gtcagggggg cgcggaagat aatccgcagc gcacattaaa agaacagaac
    11161 attttcgcgg ttctgaagca gttaggattc agttctgacc tctacgctat gcagagcgaa
    11221 atgtggttct acagcaacac gatggcggac aacattgctt atcgtgagca gattggtgcg
    11281 gagccacgta atcgtggcaa gccggtagat gatatgttgc tggtagacga aatgcagcaa
    11341 tcgctagggc gcaacccgga tggtaagcat ctgatcattc tgcataccaa aggttcgcat
    11401 tttaactaca cccagcgtta tccgcgtagc ttcgcgcagt ggaagccgga atgtattggt
    11461 gttgatagcg gctgtaccaa agcgcagatg atcaactcct atgacaactc ggtgacctat
    11521 gtggatcact ttatctccag cgtgattgat caggttcgcg ataagaaagc gattgtgttc
    11581 tacgcagctg accacggtga gtcaattaat gaacgcgagc acctgcacgg cacgccgcgt
    11641 gaactggcac cgccggagca gttccgcgta ccgatgatgg tctggatgtc agataaatat
    11701 ctggaaaatc cggccaatgc tcaggcattt gcgcagctga aaaaagaagc cgacatgaaa
    11761 gtgccacgcc gtcatgtaga gctgtacgac accatcatgg gttgtcttgg ctatacttca
    11821 ccggatggtg gaattaacga aaacaacaac tggtgtcaca tcccgcagac aaaagtggca
    11881 gcggctaact aagcggcctg ctgactttct cgccgatcaa aaggcatttt gctattaagg
    11941 gattgacgag ggcgtatctg cgcagtaaga tgcgccccgc attcggtgat tggcgcagcc
    12001 tggtagcgca cttcgttcgg gacgaagggg tcggaggttc gaatcctcta tcaccgacca
    12061 aattcgaaaa gcctgctcag cgagcaggct tttttgcatt tgaagcccat gaggatgaga
    12121 acctccgggg gcggggaggt tcgactcgag cgaagcgaga gaacgttgcg ccagcaacgg
    12181 cccgcagggc gagccacgaa gtggcgagta atcctctatc accgaccaaa ttcgaaaagc
    12241 ctgctcaacg agcaggcttt tttgcatttg tagctcatga ggatgagaac ctccgggggc
    12301 ggggaggttc gactcgacgt aggcctgata agacgcgtca gcgtcgcatc aggcaacggc
    12361 accgcactta ttgtcggatg cggcgtgaac gccttattcg acctacacgc cacacatttc
    12421 cctgccaaat ttgcgcccca tatctcacta tccattaacg gatttgtgac agaaaccatt
    12481 gtcttttttt atatttgctt aaatcttttt ttgcgttact tatggctgac cctggcattt
    12541 tccgctgtgc gttttagcgt tcatggtatt aatcgctcag atatccacct tttcctcaga
    12601 tttttttcat taaatgcata aaacttaatc accaaatgtt gctaaatatt aagctgattg
    12661 ttctggtcat gttggagtag cacaaatttc tctgctgcaa atagctgttt gaagtttttt
    12721 taatctttgt ttgtggattc tcaccgttgg tgtaaatccc ggttggctgt attgacgttt
    12781 tcacattctg ttgacagatt gtaggtcacg aggggcattt tatggaggat ccgcactgtt
    12841 acactgatgt taattagtac ggcatcccca cctcataacg ttgacccgac cgggcaaaaa
    12901 acaaaaaagg tcaggcagcg acaacccact gcaaagggtt aaaacaacaa acatcacaat
    12961 tggagcagaa taatgcgtat ttccttgaaa aagtcaggga tgctgaagct tggtctcagc
    13021 ctggtggcta tgaccgtcgc agcaagtgtt caggctaaaa ctctggttta ttgctcagaa
    13081 ggatctccgg aagggtttaa cccgcagctg tttacctccg gcaccaccta tgacgcctct
    13141 tccgtaccgc tttataaccg cctggttgaa tttaaaatcg gcaccactga agtgatcccg
    13201 ggcctcgctg aaaagtggga agtcagcgaa gacggtaaaa cctatacctt ccatctgcgt
    13261 aaaggtgtga agtggcatga caataaagaa ttcaaaccga cgcgcgaact gaacgccgat
    13321 gacgtggtgt tctcgttcga tcgtcagaaa aacgcgcaaa acccgtacca taaagtttct
    13381 ggcggtagct acgaatactt cgaaggcatg ggcttgccgg agctgatcag cgaagtgaaa
    13441 aaggtggacg acaacacagt tcagttcgtg ctgactcgcc cggaagcgcc gttcctcgct
    13501 gatctggcaa tggacttcgc ctctattctg tcaaaagaat atgctgatgc gatgatgaaa
    13561 gccggtacac cggaaaaact ggacctcaac ccaatcggaa ccggtccatt ccagttacag
    13621 cagtaccaaa aagattcccg tatccgctac aaagcgtttg atggctactg gggcaccaaa
    13681 ccgcagatcg atacgctggt cttctctatt acccctgatg cttccgtgcg ttacgcgaaa
    13741 ttgcagaaga atgaatgcca ggtgatgccg tacccgaacc cggcagatat cgctcgcatg
    13801 aagcaggata aatccatcaa cctgatggaa atgccggggc tgaacgtcgg ctacctctcg
    13861 tataacgtgc agaaaaaacc gctggatgac gtgaaagttc gccaggcact gacctacgcg
    13921 gtgaacaaag acgcgatcat caaagcggtt tatcagggcg cgggtgtatc agcgaaaaac
    13981 ctgatcccgc caaccatgtg gggctataac gacgacgttc aggattacac ctacgatcct
    14041 gaaaaagcga aagccttgct gaaagaagcg ggtctggaaa aaggtttctc catcgacctg
    14101 tgggcgatgc cggtacaacg tccgtataac ccgaacgctc gccgcatggc ggagatgatt
    14161 caggcagact gggcgaaagt gggcgtgcag gccaaaatcg tcacctacga atggggtgag
    14221 tacctcaagc gtgcgaaaga tggcgaacat cagacggtaa tgatgggctg gactggcgat
    14281 aacggggacc cggataactt cttcgccacc ctgttcagct gcgccgcctc tgaacaaggt
    14341 tctaactact caaaatggtg ctacaaaccg tttgaagatc tgattcaacc ggcgcgtgct
    14401 accgacgacc ataacaaacg cgttgaactg tacaagcaag cgcaggtggt gatgcacgat
    14461 caggctccgg cactgatcat cgctcactcc accgtgtttg aaccggtacg caaagaagtc
    14521 aaaggctatg tggttgatcc attaggcaaa catcacttcg aaaacgtctc tatcgaataa
    14581 ttaaaagcca tacaagactg atggcaaagg caaaactgcc tgatgtgctc cgcttatcag
    14641 gcctacgaaa attctgcaat gtattgaatt tgcacgattt tgtaggccgg ataaggcgtt
    14701 aacgccgcat ccggcataaa caaagcgcac tttgtcaaca atctgtatac ccggtggcgc
    14761 tgtgcctctg cgtgcagcgc catccggcag caatacttca ttctctgtcc gacaagggcg
    14821 ggaattgatt tgtgagcaat acagacacgc agttccaggc tgcgggtcac tatagagaat
    14881 ccgggttatg ttgcagttta ttctccgacg tttgggactc gtcatcccca cgtttatcgg
    14941 tattaccctt ctcacatttg cctttgtcca catgatcccg ggcgatccgg tgatgatcat
    15001 ggcaggcgaa cgtgggatct cccctgagcg tcacgcgcag ctgctggctg aactcggctt
    15061 agataaaccg atgtggcagc agtatctcca ttacatttgg ggcgtaatgc acggcgatct
    15121 aggcatttca atgaaaagcc gaattccagt atgggaagag ttcgtgccgc gctttcaggc
    15181 cacgctggaa cttggcgtct gcgcgatgat ttttgctacg gcagtcggta ttccggttgg
    15241 tgtgctggct gcggttaaac gcggttccat tttcgatcac acagcggttg gcctggcgct
    15301 gaccggctac tcgatgccga tcttctggtg gggcatgatg ctgatcatgc tggtttcggt
    15361 gcactggaac ctgacgcccg tctccggtcg cgtgagcgat atggtgttcc tcgatgactc
    15421 caatccgtta accggtttta tgctaatcga caccgccatc tggggtgaag acggcaactt
    15481 tatcgatgcc gtcgcccata tgatcttgcc tgccattgtg ctgggtacta ttccgctggc
    15541 ggtcattgtg cgtatgacac gctcctcgat gctggaagtg ctgggcgagg attacatccg
    15601 caccgcgcgc gccaaagggc taacccgcat gcgggtgatt atcgtccatg cgctgcgtaa
    15661 cgcgatgctg ccggtggtga ccgttatcgg cctgcaggtg ggaacattgc tggcgggggc
    15721 gattctgacc gaaaccatct tctcgtggcc cggtctggga cgctggttga ttgacgcact
    15781 gcaacgccgc gactatccgg tagtgcaggg cggcgtattg ctggtggcga cgatgattat
    15841 cctcgtcaac ttgctggtcg atctgctgta cggcgtggtg aacccgcgta ttcgtcataa
    15901 gaagtaaggg gacatcatgt cacaggttac tgaaaataaa gtgattagcg caccggtgcc
    15961 gatgaccccg ttacaggagt tctggcacta ttttaaacgc aacaaaggtg cggtcgtcgg
    16021 gctggtttac gtcgtcatcg tgctgttcat cgcgatcttt gccaactgga ttgcacccta
    16081 taacccggcg gaacagttcc gcgatgcact gctcgccccg ccagcctggc aggaaggcgg
    16141 cagcatggcg cacttgctgg gcaccgatga cgtaggccgt gatgtgctgt cgcgcctgat
    16201 gtacggtgcg cgcctgtcgc tgctggttgg ctgtctggta gttgtgttat cgctgattat
    16261 gggcgttatt ctcggcctga tcgccggtta ctttggcggc ctggtcgata acatcattat
    16321 gcgcgtggtc gatatcatgc tggcgctgcc aagtctgctg ctggcgctgg tgctggtggc
    16381 aattttcggc ccgtcgattg gtaacgccgc gctggcactg accttcgttg ccttgccgca
    16441 ctatgtgcgc ttaacccgcg ccgccgtgct ggtggaagtt aaccgcgatt acgtcaccgc
    16501 gtctcgcgtg gcgggtgccg gggcgatgcg tcagatgttt attaacatct tcccgaactg
    16561 ccttgcgccg ctgattgttc aggcgtcgct cggtttctct aacgccattc tcgatatggc
    16621 tgctcttggt ttcctcggca tgggggcaca gccgccaacg cctgagtggg gcaccatgct
    16681 ctccgacgtg ttgcagttcg cgcaaagcgc ctggtgggtc gtgaccttcc cgggtctggc
    16741 gatcctgctg acggtgctgg catttaacct gatgggtgac ggtctgcgtg acgcgctcga
    16801 tcccaaactg aagcagtaag aggttcgaga tggcgttatt aaatgtagat aaattatcgg
    16861 tgcatttcgg cgacgaaagc gcgccgttcc gcgccgtaga ccgcatcagc tacagcgtaa
    16921 aacagggcga agtggtcggg attgtgggtg agtccggctc cggtaagtcg gtcagttcac
    16981 tggcgattat ggggctgatt gattatccgg gccgcgtaat ggcagaaaaa ctggagttta
    17041 acggccagga tttgcagcgt atctcagaaa aagagcgccg caacctggtg ggtgccgaag
    17101 tggcgatgat cttccaggac ccgatgacca gccttaaccc gtgctacacc gtgggtttcc
    17161 agattatgga agcgattaag gtgcatcagg gcggcaacaa aagtacccgc cgtcagcgag
    17221 cgattgacct gctgaatcag gtcggtattc ccgatccggc atcgcgtctg gatgtttacc
    17281 cgcatcagct ttccggcggc atgagccagc gcgtgatgat cgccatggcg attgcctgtc
    17341 ggccaaaact gctgattgcc gatgaaccaa ccactgcgct ggacgtgacc attcaggcgc
    17401 aaatcatcga actactgctg gagctacagc agaaagagaa catggcgctg gtgttaatta
    17461 cccatgacct ggcgctggtg gcggaagcgg cacataaaat catcgtgatg tatgcaggcc
    17521 aggtggtgga aaccggtgat gcgcacgcca tcttccatgc gccgcgtcac ccgtatactc
    17581 aggcattgct gcgtgcgctg ccagaatttg ctcaggacaa agaacgtctg gcgtcgttgc
    17641 caggtgtcgt tcccggcaag tacgaccgcc cgaacggctg cctgcttaac ccgcgctgcc
    17701 cctatgccac tgacagatgt cgcgctgaag aaccggcgct gaatatgctc gctgacgggc
    17761 gtcagtccaa atgccattac ccacttgatg atgccgggag gccgacacta tgagtacgca
    17821 agaggccacc ctgcaacaac cgctgttgca ggctatcgac ctgaaaaaac attatccggt
    17881 gaagaaaggc atgttcgcgc cggaacgtct ggttaaagcg ctggatggcg tttcgtttaa
    17941 ccttgaacgt ggcaaaacgc tggcagtagt gggcgaatct ggctgcggta aatcgaccct
    18001 cggtcggttg ctgacgatga tcgaaacgcc caccggtggt gagctgtatt accaggggca
    18061 ggatctgctc aagcacgatc cgcaggcgca gaagctgcgt cggcagaaaa tccagattgt
    18121 cttccagaac ccttacggtt cgctgaatcc gcgtaaaaaa gttgggcaaa ttctcgaaga
    18181 gccgctgctt attaacacca gcttaagcaa agaacagcgt cgggaaaaag ccctgtcgat
    18241 gatggcgaaa gtcggcctga aaaccgagca ctatgaccgc tatccgcata tgttctccgg
    18301 cggacaacgt cagcgtatcg ctattgcccg tggtctgatg ctcgacccgg atgtggtgat
    18361 tgccgatgag ccggtttctg cgctggacgt ctcagtgcgt gcgcaggtgc tgaatctgat
    18421 gatggatttg cagcaggaac tggggctttc ttatgtcttt atctcgcacg acctgtcggt
    18481 tgtggagcac attgccgatg aagtgatggt gatgtacctg ggccgctgcg tggagaaggg
    18541 gacaaaggac caaatcttca ataacccgcg tcatccttac actcaggcgc tgctctccgc
    18601 gacgccgcgc ctgaacccgg acgatcgccg cgagcgcatc aagctcaccg gtgaactgcc
    18661 aagcccgctc aatccaccgc cgggttgcgc cttcaacgcc cgctgtcgtc gacgcttcgg
    18721 cccctgcacc cagttgcagc cagcactgaa agattacggc ggtcaactgg tggcctgctt
    18781 tgccgttgat caggatgaaa atccgcagcg gtaatgttca aaaccggagc cttgtgctcc
    18841 ggtttactca atcagcttca acagtggcga caagcatagc aaaatgccgt acagcagaat
    18901 cagccaggct ttaaatccgc gaagtttttc cagttgtgcg actttataga tcaggaaaaa
    18961 cggaatgagg cacgacacaa tgccatataa cgggcttccc aactgaaaga acaccagcac
    19021 cgatacacga aacgaaaccc aaatcgtcaa cgtaatgacg ataaaagcgc agatcgccag
    19081 agtcagcatg cgtgagttaa ttttcttggt atcaataatt cggcttaaca gattgagaat
    19141 aatgccttta atagcctcgt ggaaaccgag ataaatgcca aagaatgcgg tcagtacggc
    19201 aaagatattc agcaccgtag aggtgatatg aatgatatgt ccagggatca cctgcgcggc
    19261 cagcgccagt gccgagatat tttgttcaaa ggcagaaacg gcttcttcgt ggctaattga
    19321 gaaggtaaac gaaaaggcaa aaaacaggat caccgcgatg agcgtgatat aactaattcg
    19381 gtgggtacgc agcgcgagcc gggttgccag tactttatct gcttcccgtt tacgataggc
    19441 aatattcatt gggttaagta cctgaataaa taccgcagaa aagaagcaaa atggaatggt
    19501 aagcaggaca tcgcggaaaa agacggaggc ttgcgggaag gcggttatat tggcgaaatt
    19561 ccagtgcggg atcatcgcaa aaccgaacac gacaataatc cctactttga ccaccaccat
    19621 tggcccagaa atcttaaaca gtaatcgttc accaccagac gcaatcgcca ccagtacggc
    19681 gaaaatagcg actttataaa gtagagattg tgaaagatcg gcatcggtta aaccgaaggt
    19741 tttcaggtac gaggcgctgt cgaaaaccac ggagagagag tagataaaaa tcccgtggat
    19801 aatcatcaaa aagtagataa ccccgaggaa aattccccag ttcttcccca ggtaatgact
    19861 gataatatcg gtgtagtcat tacaggaatc gctttcagaa agggttttta aataaatgtc
    19921 ctgcactacc caggtggcag gataagcaat gatcgctgcg gtaataaata cccaaattcc
    19981 cttcaagcca atttgtactg gcatcagcac ggttccggca ccaatcgcca tgcctatgca
    20041 taataaaacc cagccgaagt cgtagcgtgt aaacggcaat ttctgattgt gtttcgatag
    20101 tgtgttgtgc tgcataaagt cctgtccaga aagaagtcgg cctcgcaaaa atgaataaac
    20161 ccagtttctc ttgcgcaaca ggtggagaag tcgaatacgc agtatgtaaa aaatgaggca
    20221 acagattcac tggggaggtc gcgaggaggc gcaattctac aaaattgcgc atttcactac
    20281 cagtctggag tcagcccgga tatgaactgc aactattgca aataaagaaa ttaagctgga
    20341 aggcatcgcg caatgaggaa gattgccggg tgctgacagt aaaaagcaat cgtaaaatca
    20401 gcggcaagcc ggaagggttc cggtgaggcg caatgttgcg ggggctttat ccctggtggc
    20461 attggttgct ggagagagaa aacccccgca cgttgcaggt atgtacctga caacataacg
    20521 ggggctaatc ttgaacctag accactcaag aatagccgcg aaacgttgtc attacaacac
    20581 aggcggctat atgacgctcg cagagctggg catggccttc tggcatgatt tagcggctcc
    20641 ggtcattgct ggcattcttg ccagtatgat cgtgaactgg ctgaacaagc ggaagtaacg
    20701 tgtcatgcgg gcgtcaggct gccgtaatgg caatttgcgc ccggaccagg ccgcaggggt
    20761 gaaactctgc ggcctttttc gtgcttactg cgggtaaggc acccagtcgc cgccgttcag
    20821 gcgaacgtac ggtttatcct ggtattgaat aactactgca tttgagttct cggagaccgg
    20881 tgctgtttgt ggcaacccac tggtgagttt tttccagtca acattgtctt cggtgaaaat
    20941 cttgccatca agaacgcgaa ccaccagatc ggagatagcc aggaagctgc tcggttggtc
    21001 aatgacaatc ggtgccccct gatgtggtgc cttcatgccg aagaatttca ccccaacggg
    21061 gacgtcggtg atagacgggc tagggatatc acgtaggcca gatacctgca ttctgtcgcc
    21121 cttcagcgcg ccgccgtgtt ccggcaccac gaccaccatc actttacgac ccgatttctc
    21181 cagttcagta aagaaggcgt ccagttcatc aaagaatttc tgcgcccgcg ctttgtaatc
    21241 cgctgttttg ctgacccccg gataatggtt gccgtcatgc agtggaagcg tgttgtagaa
    21301 cgtggcacta cggctatttt tatctttttc ggtaacgtcc agccagcggt taagcacggc
    21361 ggtatcgtca taaaccggcg aaccatcaaa gcccagcaaa ataaccggca gatttgtttg
    21421 atccatcaat tcagtctgca tgccgccatt ttcgcgaact tctttcaaaa aaccgccgaa
    21481 ctggccgtta tgccccatca tcaggtgctg ggtaaagccc agtttcgaaa ggttatcaaa
    21541 cagatagcag tcgttatttg ccggttgata cagattagtg tgcgaagtct gcccgcagct
    21601 ggcgcgcagt aaacggatcg ccgccgggcc actgtaggag gtggcggagt taaagttctt
    21661 gaactcaata tcgaaatgcg accacagtgg atgcgacatc aacccggcgg cttctatatc
    21721 cgactaggaa agcgaacaga tgttaatcac cagtagttca aatggctgag catcagcggg
    21781 cagcgaagac gggaaggtcg atttacgttt cgcctccgcg ttatagaaat tattcagcca
    21841 ggcgttaagg ttcgccgttg ttggcggtgc agtttgtgcg ggcatatcac ccactaccgg
    21901 tgcgccaccc gtcgccgcaa cggttgccgc tgcgttacca cccgtcgttg ttacagtggt
    21961 cgtcggttgt ccggctggcc acaaggagaa acttggtccc gccagggtaa gtacgttcag
    22021 ccatagcagt atggcaacca caaaaacggt aatgcgaatc cattgtgaca ggaataacca
    22081 ggccactaat aaaacaaaaa tggccccaat catctgccag ttaataaagc gtgtgacaag
    22141 gtcgattaaa taatcggtac tgaaccccgc cacctgcgaa ccctggctca ttatgctttc
    22201 cgggccaggc aaccaggtgt catgccagaa caaagcaaag ccgatcggca gggcaatcca
    22261 gtggcgcaag cgatgcaggc tgtagcgcgg aatgggcatc agcagaaacg cggcaaacac
    22321 caaattgagg agcggatgga agttaagata tcccgcccac aacaggccga acttaaccag
    22381 aaaatagaag ttccagccgg aaaggccgcg ccagtattgc cagagggaag aaggcatggc
    22441 ggtattttgt gtaaattgag tcattttttg gttgccctgg ctttttccgt gcggcgtaac
    22501 gtcccggccg gtttaacata acgaggttta gcaaagaaca aacgtaaggt gtcgcgaatg
    22561 cgtcgcaaag agtgccgcgc cagatagccc agcgggaaaa atatcagtgc gcaaacgaca
    22621 ataatttcaa tgatatcgct gatggtcatc atgatgagcg ctccacagca tcatctaaca
    22681 gtcgcatggg ttctggtatt cgtcgccagt ggcgaccatc gtgctcggca ttgatgaccg
    22741 gtttagaact ttgcgttaaa ggcagcggca tgccccattg ttctggggca agcaagcgca
    22801 tctgcaccag ctcggcactg atttgatcat cttcaaacca gaccatacgg tttgagaaaa
    22861 tgtcgccagt aggcaatggg aaaatatgat tcaacgcggt atccagatcg ttaatccgac
    22921 agaatgagag aaacagcacc agccgattac cgccaatggt catgatatcg ccggtacggt
    22981 tagggcgaca cagcgtcagg gcttgttcaa cgcggatacc cggtaccgga cgtagggcaa
    23041 ccagaacgcc tttaccgtgg gcaggtaata gagggttatt catcatgttg ttgacggcat
    23101 tacagaacac atcccacttc tggaaaccac gcagtttgag cggctgggtc attgacagca
    23161 aggtagtgat atcttccggc acatagcgac taaacttctg cccttgcacg ctttcgatca
    23221 tcgtcagaca acgggagagt ggcgcattcc acggaataac catatttgca ccgcaggcca
    23281 ataacaaacg ttcatcggtg gcgcgcaggc tagcggtatt ttcccgcacg aggattttca
    23341 tcgcactacc gcgctggcga cgcagggtat gaatgctgcg ggccagtggc tcgatttgcg
    23401 cattttgctg taaagaaaag accaccgtcg ccgcctgagc ggtacgggct tcattgaaca
    23461 ggacttcgtt attgttgaac agttgccagt gttccgatag cggcggcgca ccttccagta
    23521 cagcaacatt actcagaatg cgtttttcgt cgctgcgtgg ttggatctcc gcctcttcgc
    23581 tttgaactaa tgtccagata ccattttgtt gctgaacgct aagctgctga cgggcgctga
    23641 cccctttttc gttgcaccag aaggcaatat ccagcaaatg ttggtcaccc tgaaaacgca
    23701 aactggcaag accaaaaagt gaacggtatt cctcaagcaa caatgaaaat tgtttatcgt
    23761 tattatttcc gggattaatt accaaaagcg aacaatggtt taacctgctc catttattca
    23821 ttttatccaa ccatgagcga agccgctcgg caggaatgtt ttgccatgcg ttatttgcgc
    23881 aaacaagaat aaaaaggtaa ttatggggat caatagaaca ctgcaaatca cgggtcaaat
    23941 agtatagacc tttttcatga tttagcattg aaaataattt tattttttcc ggcccttgag
    24001 aatcatctaa ttgaaagatt ttcgccggat cgctgtccat gctaatgacc gcgacgtgtg
    24061 cggtttcagc ctgggatgca attgtttgat tcgccagact gatagcatct tcatggcgat
    24121 cgacgttaaa ccaccagacg ccgcctgctg gcatatgtcg cagctcatcc cataatgatg
    24181 agataccgat agagaataca gggtccacaa tgtccctcat gtcaccattt tgtctgatta
    24241 tcagtttact agcgaaagct aagaaataaa cctaccattg aaattaaaac ttatcagatt
    24301 tagcatgtga atcaatttag aaggtcacaa gacgtgtgat tttagtcttt tcgtttttaa
    24361 ctttttctgt tgcgtaacgg aaagtcaaaa agtgagcaaa ttcccgtctc gccgtaaaca
    24421 ataaaccggc gaaatgctca cggttagaat tgtctcatga acggtacggt tatttcatag
    24481 ggatcaagca aaatgaataa caatgaacca gatactctgc ctgatcccgc gataggctat
    24541 atcttccaga atgatattgt ggcgttaaag caggcatttt cactgcctga tattgattat
    24601 gccgatattt cccaacgcga acagttggcc gcggcattaa aacgctggcc gttgctggca
    24661 gagtttgcgc aacaaaagta ggggattggt gaatggccgt actgggattg cggggaggcg
    24721 tggggacaac aaccatcacc gccgcattag cctggtcatt acaaatgttg ggagaaaatg
    24781 ttctggtggt cgatgcctgc ccggacaact tgttgcgcct gtcatttaat gttgatttta
    24841 cccaccgtca gggctgggcc agagcgatgc tggatggcca ggactggcgt gacgctgggt
    24901 tgcgctacac ctcgcagctc gatttgctgc cttttggtca gttatccatt gaagaacaag
    24961 aaaatccaca gcactggcaa acccggctga gcgatatttg ctccggctta cagcaactaa
    25021 aagccagcgg gcgttaccag tggattttaa tcgacttacc gcgtgatgcc tcgcagataa
    25081 cccaccagct gctgagtttg tgcgatcact cgctggcaat cgtcaatgtg gatgccaact
    25141 gccatatccg actgcatcag caagcgctgc cggatggcgc acatattttg attaatgact
    25201 tccgtattgg cagtcaggtt caggacgata tttaccagct ttggttgcaa agccagcgcc
    25261 gattactgcc gatgctcatt catcgtgatg aagcgatggc tgaatgcctg gcggctaagc
    25321 aaccagtagg tgaatatcgc agtgatgcgc tggcggctga agagatactg acgctggcga
    25381 actggtgcct gttgaactac tccgggctga aaacgccagt cgggagtgca tcatgagtat
    25441 cctgacccgg tggttgctta tcccgccggt caacgcgcgg cttatcgggc gttatcgcga
    25501 ttatcgtcgt cacggtgcgt cggctttcag cgcgacgctc ggctgtttct ggatgatcct
    25561 ggcctggatt tttattccgc tggagcaccc gcgctggcag cgtattcgcg cagaacataa
    25621 aaacctgtat ccgcatatca acgcctcgcg tccgcgtccg ctggacccgg tccgttatct
    25681 cattcaaaca tgctggttac tgatcggtac atcgcgcaaa gaaacgccga aaccgcgcag
    25741 gcgggcattt tcaggtctgc agaatattcg tggacgttac catcaatgga tgaacgagct
    25801 gcctgagcgc gttagccata aaacacagca tcttgatgag aaaaaagagc tcggtcattt
    25861 gagtgccggg gcgcggcggt tgatcctcgg tatcatcgtc accttctcgc tgattctggc
    25921 gttaatctgc gttactcaac cgtttaaccc gctggcgcag tttatcttcc tgatgctgct
    25981 gtggggtgta gcgctgatcg tacggcggat gccggggcgc ttctcggcgc taatgttgat
    26041 tgtgctgtcg ctgaccgttt cttgccgtta tatctggtgg cgttacacct ctacgctgaa
    26101 ctgggacgat ccggtcagcc tggtgtgcgg gcttattctg ctcttcgctg aaacgtacgc
    26161 gtggattgtg ctggtgctcg gctacttcca ggtagtatgg ccgctgaatc gtcagccggt
    26221 gccattgccg aaagatatgt cgctgtggcc gtcggtggat atctttgtcc cgacttacaa
    26281 cgaagatctc aacgtggtga aaaatactat ttacgcctcg ctgggtatcg actggccgaa
    26341 agacaagctg aacatctgga tcctcgatga cggcggtagg gaagagtttc gccagtttgc
    26401 gcaaaacgtg ggggtgaaat atatcgcccg taccactcat gaacatgcga aagcgggcaa
    26461 catcaacaat gcgctgaaat atgccaaagg cgagttcgtg tcgattttcg actgcgacca
    26521 cgtaccaacg cgatcgttcc tgcaaatgac catgggctgg ttcctgaaag agaaacagct
    26581 ggcgatgatg cagacgccgc accacttctt ctcgccggac ccgtttgaac gcaacctggg
    26641 gcgttttcgt aaaacgccga acgaaggcac gctgttctat ggtctggtgc aggatggcaa
    26701 cgatatgtgg gacgccactt tcttctgcgg ttcctgtgca gtaattcgtc gcaaaccatt
    26761 ggatgaaatt ggcggtattg ctgtcgaaac ggtaaccgaa gatgcgcaca cgtctctgcg
    26821 cctgcaccgt cgtggctaca cctctgcata tatgcgtatt ccgcaggcgg cggggctggc
    26881 gaccgaaagt ctgtcggcgc atatcggtca gcgtattcgc tgggcacgcg ggatggtgca
    26941 aatcttccgt ctcgataacc cgcttaccgg taaagggctg aaattcgccc agcggctgtg
    27001 ctacgtcaac gccatgttcc acttcttgtc gggcattcca cgactgatct tcctgactgc
    27061 gccgctggcg ttcctgctgc ttcatgccta catcatctat gcgccagcgt tgatgatcgc
    27121 cctgttcgtg ctgccgcata tgatccatgc cagcctgacc aactccaaga tccagggcaa
    27181 atatcgccac tctttctgga gtgaaatcta cgaaacggtg ctggcgtggt atatcgcacc
    27241 accgacgctg gtggcgctga ttaacccgca caaaggcaaa tttaacgtca ccgccaaagg
    27301 tggactggtg gaagaagagt acgtcgactg ggtgatctcg cggccctaca tcttccttgt
    27361 cctgctcaac ctggtgggcg ttgcggtagg catctggcgc tacttctatg gcccgccaac
    27421 cgagatgctc accgtggtcg tcagtatggt gtgggtattc tacaacctga ttgttcttgg
    27481 cggcgcagtt gcggtatcgg tagaaagcaa acaggtacgc cgatcgcacc gcgtggagat
    27541 gacgatgccc gcggcaattg cccgcgaaga tggtcacctc ttctcgtgta ccgttcagga
    27601 tttctccgac ggtggtttgg ggatcaagat caacggtcag gcgcagattc tggaagggca
    27661 gaaagtgaat ctgttgctta aacgcggtca gcaggaatac gtcttcccga cccaggtggc
    27721 gcgcgtgatg ggtaatgaag ttgggctgaa attaatgccg ctcaccaccc agcaacatat
    27781 cgattttgtg cagtgtacgt ttgcccgtgc ggatacatgg gcgctctggc aggacagcta
    27841 cccggaagat aagccgctgg aaagtctgct ggatattctg aagctcggct tccgtggcta
    27901 ccgccatctg gcggagtttg cgccttcttc ggtgaagggc atattccgtg tgctgacttc
    27961 tctggtttcc tgggttgtat cgtttattcc gcgccgcccg gagcggagcg aaacggcaca
    28021 accatcggat caggctttgg ctcaacaatg atgataacgc gatgaaaaga aaactattct
    28081 ggatttgtgc agtggctatg gggatgagtg cgttcccctc tttcatgacg caggcgacgc
    28141 cagcaacgca accactgatc aatgctgagc cagctgtagc cgcccagacg gaacaaaatc
    28201 cgcaggtggg gcaagtgatg ccgggcgtgc agggcgctga tgcgccagtc gtggcgcaga
    28261 acggtccttc gcgtgatgtg aagctgacct ttgcgcaaat tgcgccgccg ccgggcagca
    28321 tggtgctacg tggcattaac ccgaacggca gcattgagtt tggtatgcgc agcgatgaag
    28381 tggtgacgaa ggcgatgctc aacctcgaat acacgccatc gccatcgtta ctgcctgtcc
    28441 agtcgcagtt aaaggtttat ctcaatgatg agctgatggg cgtgctgcca gtgaccaaag
    28501 aacagttggg taaaaaaacg ctggcgcaaa tgcccattaa cccactgttt attaccgact
    28561 tcaaccgtgt gcggctggag tttgtcggcc attatcagga cgtgtgcgaa aacccggcca
    28621 gcaccacgct ttggctggat gttgggcgga gcagtggact ggatctgacc tatcagaccc
    28681 tgaatgtgaa gaatgacctg tcacacttcc cggtgccatt ctttgatccg cgtgataacc
    28741 gcaccaacac cttgccgatg gtctttgcgg gtgcgccgga tgttgggctg caacaagcct
    28801 ctgccattgt cgcctcgtgg tttggttcgc gttctggctg gcgtgggcag aacttcccgg
    28861 tgctctataa ccaactgccg gatcgtaatg ccattgtctt tgcaaccaac gacaaacggc
    28921 cggacttcct gcgcgatcat ccggcggtaa aagccccggt gattgagatg attaaccatc
    28981 cgcagaatcc ttacgtcaaa ctgctggtgg tgtttggtcg tgacgacaaa gacctgttgc
    29041 aggcagcgaa aggtatcgct cagggtaaca ttctgttccg tggtgaaagc gtggtagtga
    29101 atgaagtgaa accgctgcta ccgcgtaagc cgtacgatgc gccgaactgg gtacgtaccg
    29161 atcgtccggt cacatttggc gaactgaaaa cctatgaaga acagttacaa tccagcggtc
    29221 ttgagccagc agcgattaac gtttcgctaa acctgccgcc ggatctctac ctgatgcgca
    29281 gtaccggcat tgatatggat attaattacc gctacaccat gccgccggtg aaagacagtt
    29341 cgcggatgga tatcagcctg aataaccagt tcctgcaatc cttcaacctg agcagcaaac
    29401 aggaggcgaa ccgcctgctg ctgcggattc cggtattaca aggtttgctg gatggcaaaa
    29461 cagatgtctc tattccggcg ctgaaactgg gcgcgaccaa ccagctgcgc ttcgactttg
    29521 agtatatgaa cccgatgccg ggcggttcgg tggataactg tattaccttc cagccggtgc
    29581 agaatcatgt ggtgattggt gacgactcca ccatcgactt ctcgaagtat taccacttca
    29641 tcccgatgcc ggatctacgc gcctttgcta acgcgggctt cccattcagc cggatggcgg
    29701 atctgtcgca aaccatcacc gtgatgccga aagcgcctaa cgaagcacag atggaaacgt
    29761 tgctgaatac tgttggtttt atcggcgcac agacgggctt cccggcgatt aatctgacgg
    29821 tgaccgatga tggcagcacc attcagggca aagatgccga catcatgatc atcggtggta
    29881 tcccggacaa actgaaagac gataagcaga tcgacctatt ggtgcaggcg accgaaagct
    29941 gggtgaaaac accgatgcgc cagaccccgt tccccggcat tgtgccggac gagagcgatc
    30001 gcgcggcaga aacccagtca acgctgacct cttccggtgc gatggcggcg gtgattggct
    30061 tccagtcgcc gtataacgac cagcgcagcg tgattgcgct gctggcagat agcccacgcg
    30121 gttatgaaat gcttaacgat gcggtgaacg atagcggcaa acgcgccacc atgttcggtt
    30181 cggtcgcggt gatccgcgag tccggtatca acagcctacg tgttggcgac gtttattacg
    30241 taggtcatct gccgtggttc gagcgcttgt ggtatgcgct ggcaaaccat ccgattctgc
    30301 tggcggtgct ggcggctatc agtgtgatat tgctggcatg ggtactgtgg cgtctgctgc
    30361 gaattattag tcgtcgtcgt cttaacccgg ataacgagta attgaagatg aatgtgttgc
    30421 gtagtggaat cgtgacgatg ctgctgttgg ctgcctttag tgttcaggca gcctgtacct
    30481 ggcctgcctg ggagcagttt aaaaaggatt acatcagtca ggaagggcgc gtcatcgacc
    30541 ccagcgacgc gcgcaaaatc accacctccg aagggcaaag ttacggtatg ttctttgccc
    30601 tggcggctaa cgaccgtgta gctttcgata atattctcga ctggacgcag aacaatctcg
    30661 ctcagggttc tttaaaagaa cgtttgcccg cctggctgtg gggcaagaaa gagaacagta
    30721 agtgggaagt gctggacagc aattcggcct ccgatggtga tgtctggatg gcctggtcgt
    30781 tgctggaggc ggggcgtttg tggaaagagc agcgttatac cgacatcggc agcgcgttgc
    30841 taaaacgtat cgcgcgggag gaagtggtga cggtgcctgg gctgggttcc atgttgttac
    30901 cgggcaaagt gggttttgct gaggataaca gctggcgttt taaccccagc tacctgccgc
    30961 cgacgctggc gcagtatttc acccgctttg gcgcgccgtg gaccacgctg cgcgaaacca
    31021 atcaacgttt attgctggaa accgccccga aaggtttttc gccagactgg gtgcgctatg
    31081 agaaagacaa aggctggcag ctaaaagccg aaaaaacatt gatcagcagc tacgacgcta
    31141 tccgcgttta catgtgggta ggcatgatgc ctgacagcga tccgcaaaaa gcgcggatgc
    31201 tcaaccggtt taaaccgatg gcgacattca ctgagaaaaa cggttatccg ccggaaaaag
    31261 tggatgtggc tacggggaaa gcgcagggta aaggaccggt cggtttttct gccgccatgc
    31321 tgcccttttt acaaaaccgc gatgcgcagg ccgttcagcg ccagcgcgtg gccgataact
    31381 ttcccggcag cgatgcctat tacaactatg tgctgaccct gtttggacaa ggctgggatc
    31441 aacaccgttt ccgcttctcg acaaaaggtg agttattacc tgactggggc caggaatgcg
    31501 caaattcaca ctaaacatat tcacgctttc cctcggtctg gccgtcatgc cgatggtcga
    31561 ggcagcacca accgctcagc aacagttgct ggagcaagtt cggttaggcg aagcgaccca
    31621 tcgtgaagat ctggtgcaac agtcgttata tcggctggaa cttattgatc cgaataaccc
    31681 ggacgtcgtt gccgcccgtt tccgttcttt gttacgtcag ggcgatattg atggcgcgca
    31741 aaaacagctc gatcggctgt cgcagttagc gccgagttca aatgcgtata aatcgtcgcg
    31801 gactacgatg ctactttcca cgccggatgg tcgtcaggca ctgcaacagg cacgattgca
    31861 ggcgacgacc ggtcatgcag aagaagctgt ggcgagttac aacaaactgt tcaacggtgc
    31921 gccgccggaa ggtgacattg ctgtcgagta ctggagtacg gtggcgaaaa ttccggctcg
    31981 ccgtggcgaa gcgattaatc agttaaaacg catcaatgcg gatgcaccgg gcaatacggg
    32041 cctgcaaaac aatctggcgc tattgctgtt tagtagcgat cgccgtgacg aaggttttgc
    32101 cgtcctggaa cagatggcaa aatcgaacgc cgggcgcgaa ggggcctcta aaatctggta
    32161 cgggcagatt aaagacatgc ccgtcagtga tgccagtgtg tcggcgctga aaaaatatct
    32221 ctcgatcttt agtgatggcg atagcgtggc ggctgcgcaa tcgcaactgg cagaacagca
    32281 aaaacagctg gccgatcctg ctttccgcgc tcgtgcgcaa ggtttagcgg cggtggactc
    32341 tggtatggcg ggtaaagcca ttcccgaact acaacaggcg gtgcgggcga acccgaaaga
    32401 cagtgaagct ctgggggcgc tgggccaggc gtattctcag aaaggcgatc gcgccaatgc
    32461 agtggcgaat ctggaaaaag ccctcgcact ggacccgcac agcagcaaca acgacaaatg
    32521 gaacagtctg ctgaaagtaa accgctactg gctggcgatc cagcagggcg atgctgcgct
    32581 gaaagccaat aatcctgacc gggcagaacg cctgttccag caggcgcgta atgtcgataa
    32641 caccgacagt tatgcagtgc tggggctggg cgatgtggcg atggcgcgaa aagattatcc
    32701 cgccgccgaa cgttattatc agcagacctt gcgtatggac agcggcaaca ctaacgccgt
    32761 gcgcgggctg gcaaatattt accgccagca atcgccagaa aaagctgaag cgtttatcgc
    32821 ctcgctctct gccagtcagc ggcgtagcat tgatgatatc gaacgcagcc tgcaaaacga
    32881 ccgtctggca cagcaggcag aggcactgga aaaccagggc aaatgggcgc aggcggcagc
    32941 acttcagcgg caacgactgg cgctggaccc cggcagcgta tggattactt accgactttc
    33001 gcaggatctc tggcaggccg gacaacgcag ccaggccgat acgttaatgc gcaatctggc
    33061 gcagcagaag ccgaacgacc cggagcaggt ttacgcttac gggctgtacc tctctggtca
    33121 tgaccacgac agagcggcgc tggcgcatat caacagcctg ccgcgcgcgc agtggaacag
    33181 caatattcag gagctggtta atcgactgca aagcgatcag gtgctggaaa ccgctaatcg
    33241 cctgcgagaa agcggcaaag aagctgaagc ggaagcgatg ctgcgtcagc aaccaccttc
    33301 cacgcgtatt gacctcacgc tggctgactg ggcgcagcag cgacgtgatt acaccgccgc
    33361 ccgcgctgca tatcagaatg tcctgacgcg ggagccaact aacgccgatg ccattctggg
    33421 gctgacggaa gtggatattg ctgccggtga cacagcggcg gcacgtagcc agctggcgaa
    33481 actgcccgct accgataacg cctcgctgaa cacacagcgg cgcgtggcgc tggcgcaggc
    33541 gcagcttgga gataccgcag cggcgcagca gacgtttaat aagttgatcc cgcaggcaaa
    33601 atctcagcca ccgtcgatgg aaagcgcgat ggtgctgcgc gacggtgcga agtttgaagc
    33661 gcaggcgggc gatccaaagc aggcgctgga aacctacaaa gacgccatgg tcgcatccgg
    33721 tgtgactacg acgcgtccgc aggataacga cacattcacc cgactgaccc gtaacgacga
    33781 gaaagatgac tggctgaaac gcggcgtgcg cagcgatgcg gcggacctct atcgccagca
    33841 ggatcttaac gtcacccttg agcatgatta ttggggatcg agcggcaccg gtggttactc
    33901 cgatctgaaa gcgcacacca ctatgttgca ggtggacgcg ccgtattctg acgggcggat
    33961 gttctttcgc agtgatttcg tcaatatgaa cgtcggcagt ttctccacta atgccgatgg
    34021 taaatgggat gataactggg gcacctgtac attacaggac tgtagcggca accgcagcca
    34081 gtcggattcc ggtgccagcg tggcggtcgg ctggcgaaat gacgtctgga gctgggatat
    34141 cggcaccacg ccgatgggct tcaacgtggt ggatgtggtc ggcggcatca gttacagcga
    34201 tgatatcggg ccgctgggtt acaccgttaa cgcccaccgt cggcccatct ccagttcttt
    34261 gctggccttt ggtgggcaaa aagactcccc gagcaatacc gggaaaaaat ggggcggtgt
    34321 gcgtgccgac ggcgtggggc taagcctgag ctacgataaa ggtgaagcaa acggcgtctg
    34381 ggcatcgctt agtggcgacc agttaaccgg taaaaatgtc gaagataact ggcgcgtgcg
    34441 ctggatgacg ggctattact ataaggtcat caaccagaac aatcgccgcg tcacaatcgg
    34501 cctgaacaac atgatctggc attacgacaa agacctgagt ggctactcac tcggtcaggg
    34561 cggttactac agcccgcagg aatacctgtc gtttgccata ccggtgatgt ggcgggagcg
    34621 cacggaaaac tggtcgtggg agctgggggc gtctggctcg tggtcgcatt cacgcaccaa
    34681 aaccatgccg cgttatccgc tgatgaatct gatcccgacc gactggcagg aagaagctgc
    34741 gcggcaatcc aacgatggcg gcagcagtca gggcttcggc tacacggcgc gggcattact
    34801 tgaacgacgt gttacttcca actggtttgt tggcacggca attgatatcc agcaggcgaa
    34861 agattacgca cccagccatt tcctgctcta cgtacgttat tccgccgccg gatggcaggg
    34921 tgacatggat ttaccgccgc agccgctgat accttacgcc gactggtaag ttttcagata
    34981 gcgcctctct taatgccgct gcgatcgggt atactcgggc ggcaatctgg gatttccggg
    35041 gggagacaat ttgcgcgtaa gtcgctcgtt aacaatcaag cagatggcaa tggtggcagc
    35101 cgttgtcctg gtgttcgttt ttattttttg caccgttttg ctgttccatc tggtccaaca
    35161 gaatcgctat aacacggcta cgcaactgga aagcattgct cgctctgtcc gcgaaccctt
    35221 atcttcagct attttgaaag gcgatattcc cgaagcggaa gctattcttg ccagcattaa
    35281 accggcaggc gtggtcagcc gtgccgatgt agtgctgcct aaccagttcc aggcgctgcg
    35341 taaaagtttt attccagagc gcccggtgcc ggtaatggtt actcgcctgt ttgagctacc
    35401 ggttcaaatc tcgctgggcg tttactcgct cgaacgtccg gcaaacccgc agccaattgc
    35461 ctatctggta ctacaggcgg attccttccg tatgtataag ttcgtgatga gcaccctctc
    35521 aacgttagtg accatttact tacttttgtc gcttatcctg accgtcgcca tcagctggtg
    35581 cattaaccgc ctgattttgc atccgttacg caatattgct cgcgaactta acgccatccc
    35641 agcccaggag cttgttggtc accaactggc attaccgcgt ctgcatcagg acgatgaaat
    35701 cggtatgttg gtgcgcagtt acaacctcaa ccagcaattg ctgcagcgcc attatgaaga
    35761 acagaacgaa aatgcgatgc gcttcccggt gtcggatttg ccgaacaaag ccttgctgat
    35821 ggagatgctg gagcaggttg tcgcgcgtaa acaaaccacc gcgctgatga tcatcacctg
    35881 tgaaaccctg cgtgatactg cgggcgtgct gaaagaggcg caacgagaaa ttctgctgct
    35941 gacgctggtg gaaaaactca aatcggtact gtcgccacgt atgatcctcg cgcagattag
    36001 cggttatgac tttgctgtca ttgccaacgg tgtacaggaa ccgtggcacg caatcacctt
    36061 aggtcagcaa gtgctcacta tcatgagcga gcgcctgccg attgaacgta ttcaactccg
    36121 tccgcactgt agcattggcg tggcgatgtt ctacggcgat ctcaccgccg aacagcttta
    36181 cagtcgcgct atttctgcgg catttaccgc tcgccataaa ggcaagaatc agattcagtt
    36241 ctttgatccg cagcagatgg aagccgccca gaagcggttg acggaagaga gcgatatcct
    36301 taatgcactg gaaaatcatc agtttgctat ttggttacag ccacaggtcg agatgaccag
    36361 cggaaaactg gtcagtgcgg aagtgttact gcgtatccag caaccggatg gcagttggga
    36421 cctgccggat ggcttaatcg atcgcattga gtgctgtggg ctgatggtta ccgtcggtca
    36481 ctgggtgctg gaagagtcct gtcgattgct tgcagcctgg caagagcgcg gcattatgct
    36541 gcccttgtcg gtaaacctct ctgcgctgca actgatgcac ccaaatatgg tggcggatat
    36601 gctggaactg ttaacccgct atcgcattca gccgggaaca ctgattctgg aagtgacaga
    36661 aagccgacgt attgacgacc ctcatgctgc ggtggcaatc ctccgtccgc tgcgcaatgc
    36721 cggagttcgg gtggcgctgg atgatttcgg catgggctac gcagggctgc gtcagctgca
    36781 gcatatgaaa tcgttgccaa tcgacgtact gaaaatcgac aaaatgtttg ttgaaggctt
    36841 gccggaagat agcagcatga ttgctgcaat tatcatgctg gcgcagagcc tgaacttaca
    36901 aatgattgcc gaaggcgtgg agactgaagc acaacgcgac tggctggcaa aagcgggcgt
    36961 tggtattgcc cagggcttcc tttttgctcg cccactccct attgaaatct tcgaagagag
    37021 ttacctggaa gaaaagtagc taccccaaac tgattacaaa actttaaaaa gtgctggttt
    37081 gtgcgagcca gctcaaactt tttaaccttt ttgtttcaat tatgatccag gtacatttct
    37141 gtgatgttgt ctgggtgtta ttttaaggcc gcaggtaccc cataacctta caagacctgt
    37201 ggttttacta aaggacaccc tatgaaaacc tctctgttta aaagccttta ctttcaggtc
    37261 ctgacagcga tagccattgg tattctcctt ggccatttct atcctgaaat aggcgagcaa
    37321 atgaaaccgc ttggcgacgg cttcgttaag ctcattaaga tgatcatcgc tcctgtcatc
    37381 ttttgtaccg tcgtaacggg cattgcgggc atggaaagca tgaaggcggt cggtcgtacc
    37441 ggcgcagtcg cactgcttta ctttgagatt gtcagtacca tcgcgctgat tattggtctt
    37501 atcatcgtta acgtcgtgca gcctggtgcc ggaatgaacg tcgatccggc aacgcttgat
    37561 gcgaaagcgg tagcggttta cgccgatcag gcgaaagacc agggcattgt cgccttcatt
    37621 atggatgtca tcccggcgag cgtcattggc gcatttgcca gcggtaacat tctgcaggtg
    37681 ctgctgtttg ccgtactgtt tggttttgcg ctccaccgtc tgggcagcaa aggccaactg
    37741 atttttaacg tcatcgaaag tttctcgcag gtcatcttcg gcatcatcaa tatgatcatg
    37801 cgtctggcac ctattggtgc gttcggggca atggcgttta ccatcggtaa atacggcgtc
    37861 ggcacactgg tgcaactggg gcagctgatt atctgtttct acattacctg tatcctgttt
    37921 gtggtgctgg tattgggttc aatcgctaaa gcgactggtt tcagtatctt caaatttatc
    37981 cgctacatcc gtgaagaact gctgattgta ctggggactt catcttccga gtcggcgctg
    38041 ccgcgtatgc tcgacaagat ggagaaactc ggctgccgta aatcggtggt ggggctggtc
    38101 atcccgacag gctactcgtt taaccttgat ggcacatcga tatacctgac aatggcggcg
    38161 gtgtttatcg cccaggccac taacagtcag atggatatcg tccaccaaat cacgctgtta
    38221 atcgtgttgc tgctttcttc taaaggggcg gcaggggtaa cgggtagtgg ctttatcgtg
    38281 ctggcggcga cgctctctgc ggtgggccat ttgccggtag cgggtctggc gctgatcctc
    38341 ggtatcgacc gctttatgtc agaagctcgt gcgctgacta acctggtcgg taacggcgta
    38401 gcgaccattg tcgttgctaa gtgggtgaaa gaactggacc acaaaaaact ggacgatgtg
    38461 ctgaataatc gtgcgccgga tggcaaaacg cacgaattat cctcttaatc tcatcactta
    38521 tgcccgcact cccttccccg agtgcgggtg tttgcgcata attgacccct gtgcctgaac
    38581 ttaccacctg ggtgagttca ggtttatttc acttcttccg tgacattttc atgttcttgc
    38641 ggtctaacac gaagtgtttt taacgtcatt tagactgacc gacaacgggc agttttttta
    38701 ttaccaggat agttgatcag gggttcacat gcagggcaca aaaattcgac ttttagcggg
    38761 cggtttgctg atgatggcca ctgctggcta tgtgcaggca gatgcgctcc agcctgatcc
    38821 agcatggcaa caggggacgc tttccaacgg tttacagtgg caagtgctga ccacccccca
    38881 gcgtcccagc gatcgtgttg aaattcgcct gctggttaat accggttcgc tcgccgaaag
    38941 tacacaacag agcggttaca gtcacgccat ccctcgtatt gcgctaacgc aaagcggtgg
    39001 ccttgacgca gcacaggcgc gttcattgtg gcagcagggg atcgacccta aacgcccgat
    39061 gccgccggta attgtctcgt atgacactac gctgtttaat ctgagtttgc ccaataaccg
    39121 taacgatttg ctgaaagagg cgctctctta cctggcaaat gccactggca aactgactat
    39181 cacaccagaa accatcaacc acgcgctgca aagtcaggac atggtggcaa cctggcctgc
    39241 cgatactaaa gagggctggt ggcgttatcg tctgaaagga tcaaccttgt taggtcacga
    39301 tcctgccgat ccgctgaaac aacccgttga agcggaaaaa attaaagatt tctatcagaa
    39361 atggtacacc ccggatgcaa tgacgctact ggtggtggga aacgtggatg cgcgctcggt
    39421 tgtcgaccaa atcaacaaaa cgtttggcga actgaaaggc aaacgtgaaa cgccagctcc
    39481 ggtgccgacg ctttctccgc tgcgtgcgga agcggtgagt attatgactg acgcggtgcg
    39541 tcaggaccgg ttatctatca tgtgggatac gccgtggcag ccgattcgtg aatcagccgc
    39601 actgctgcgc tactggcgtg cggacctggc ccgcgaggcg ctgttctggc atgttcagca
    39661 agcgttaagc gccagtaaca gcaaagacat cggtcttgga tttgactgcc gtgtgctgta
    39721 tctgcgtgcg cagtgtgcca tcaacatcga atcaccaaac gacaagctga acagcaacct
    39781 taatctggtg gcgcgtgaac tggcgaaggt tcgcgataaa ggtctgccgg aagaagagtt
    39841 caatgcgtta gtggcgcaaa agaaactgga gctgcagaaa ctgtttgccg cctatgcgcg
    39901 ggctgatacc gatattctga tgggtcagcg gatgcgttcg ttgcaaaatc aggtcgtcga
    39961 tatcgcgccg gagcagtatc agaaactgcg gcaggatttc cttaacagcc tgacggtgga
    40021 gatgttaaat caggatctgc gtcagcagtt gtcgaatgat atggcgttaa tactgctgca
    40081 gccgaaaggc gagccggaat ttaacatgaa agcgttgcag gcggcctggg atcaaatcat
    40141 ggccccatct accgccgctg cgaccacctc tgtcgccacg gatgacgtac atcctgaagt
    40201 gacggatatt ccacctgcac agtaatgcct gatggtgatg agttagcaca atcatcaggt
    40261 atttatggat gagctggata gaggggtaac actttatcca gccttttgca tatgctgctt
    40321 ttacgctggc atcgcctcac gcgggataat cgcgccgcga tactgaataa cggtacttgc
    40381 ggtcaggtgc ccgcgtttcg ccgcgttttc cgcactgccg cccgttaaac gtaccgccag
    40441 ataaccggca ctgaaagagt cgccagctgc ggtggtatcg atcacttttt ctttcggcag
    40501 tttcaccgcc ggaacatcca ctaacccttc gccagcaatg gacaccaggc aagaatccgc
    40561 cccgcgtttc accaccactt ctttcacgcc cgcgttatgg gtgcgcgcaa tgacgtcttc
    40621 caccggctgt tgaccccaca gcgcgtcttc gtcgtccagc gtcaggaagg cgatatccgt
    40681 gcattccagc atttgttggt acacctgctg tgtctcttct ttgctggccc acaggcgcgg
    40741 acgatagtta ttgtcgaaaa tcacttttcc gccgttggcg cggcattcgc gcagcaggga
    40801 aagcagcttt tcgcggctgg tcgggcttaa gatcgccagg ctaatcccgc tcaggtagag
    40861 ataatcgaaa ttcgccagct cttcgcaaat cgccgcagac tgctcgctct ccagccagaa
    40921 tttggcagcg gcttcgttac gccagtagta gaacgtacgt tcaccggtgc tgtcggtttc
    40981 aatgtagtaa aggcccggca gacggttttc catccgttgg gtcagggaag tatcaacgtt
    41041 ctcgccgtgc caggcgtcca gcatttgctg gctaaaactg tccgttccca gcgccgttac
    41101 gtaatgaacg gttaatgccg caggatcgac ctgacgggcg atatagacgg aagtgttcag
    41161 ggtatcgccg ccgaaaccgc gcttaacgtc cgcgcctttc tcggaaagct caatcatgca
    41221 ttcgccaatc acggcaatct ttttggacat agtcgtgaac ctgatctgta aaaaattagc
    41281 gttagtttgc gctgtggtgg tttgctggtc aaccatatta aaacagtgtt ccattatttt
    41341 tttgagccag gacgtattcc tgaaagattc cgttgtggag tgaggaaatt taccccggcc
    41401 aggcggtaaa gttctgccct tacgcgccga taatctttgt cgagtccggg cagcatcact
    41461 tttaaacaca ggacatcttt gatgataagg caggttatcc agcgaataag caaccctgaa
    41521 gcaagcatcg agagcttgca ggaacggcgt ttttggttgc agtgtgagcg tgcttacacc
    41581 tggcagccga tctatcaaac atgcggacgg ttaatggccg tggagctatt aacggtggtc
    41641 acgcatccct tgaacccttc gcaacgcctg ccgccggatc gctattttac tgaaatcacc
    41701 gtcagccatc ggatggaggt tgtgaaagag cagattgatt tgctggcgca aaaagccgac
    41761 ttctttatag agcacggcct gctggcatcg gtcaatattg atggccctac gctcatcgcc
    41821 ctgcgtcagc aaccaaaaat cctgcgccag attgagcgtc ttccctggct gcgtttcgaa
    41881 ctggtggagc atatccgtct gccgaaagat tcaacctttg cctcgatgtg tgaatttggc
    41941 ccgctgtggc tggatgattt tggtaccggg atggcaaatt tctctgcact aagtgaagtg
    42001 cgttatgact acatcaaaat cgcgcgagaa ctgtttgtga tgctgcgtca gtcgccggaa
    42061 ggacgcacac tcttttctca gcttttacat ctaatgaatc gctattgtcg cggggtgatt
    42121 gtcgagggcg tagaaacgcc ggaagagtgg cgtgatgttc agaactcgcc cgcattcgcc
    42181 gcacaaggct ggtttctttc acgcccggca ccgatagaaa cgctgaatac ggcggttctg
    42241 gcgctataag ctgcctcatt ttccgcctgg ctggactatc tttaggactg gcacaggaag
    42301 aatatgagga agcgaacgat gagcaaggca ggcaaaataa ccgctgcgat ttcagtggct
    42361 ttcttgttgt tgattgtcgt ggcgatcatt ttgattgcaa cttttgactg gaatcgactc
    42421 aaaccgacca tcaaccagaa agtctctgcg gagttgaatc gtccgttcgc tatccgtggc
    42481 gatctgggcg tggtgtggga gcggcaaaaa caagaaactg gctggcgcag ctgggtgccg
    42541 tggccccatg tacacgcgga agacatcatt cttggcaatc caccggatat tcccgaagtc
    42601 acgatggtgc atttgccacg cgtagaggca acgctggccc cgctggcgct gctgaccaaa
    42661 acggtctg
//
LOCUS       DAPGUL010000027        42219 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.027, whole genome shotgun sequence.
ACCESSION   DAPGUL010000027 DAPGUL010000000
VERSION     DAPGUL010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 42219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42219
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.027"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            14..620
                     /locus_tag="RHX21_001636"
                     /pseudo
     CDS             14..620
                     /locus_tag="RHX21_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001544752.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            723..1226
                     /locus_tag="RHX21_001637"
     CDS             723..1226
                     /locus_tag="RHX21_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HDV1986837.1"
                     /translation="MGMIGYFAEIDSEKINQLLESTEKPLMDNIHDTLSGLRRLDIDK
                     RWDFLHFGLTGTSAFDPAKNDPLSRAVLGEHSLEDGIDGFLGLTWNQELAATIDRLES
                     LDRSELRKQFSIKRLNEMEIYPGVTFSEELEGQLFASIMLDMEKLISAYRRMLRQGNH
                     ALTVIVG"
     gene            complement(1293..2750)
                     /gene="nuoN"
                     /locus_tag="RHX21_001638"
     CDS             complement(1293..2750)
                     /gene="nuoN"
                     /locus_tag="RHX21_001638"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416779.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoN"
                     /protein_id="HDV1986838.1"
                     /translation="MTITPQNLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIG
                     LNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNK
                     DEFYLLVLIAALGGILLANANHLASLFLGIELISLPLFGLVGYAFRQKRSLEASIKYT
                     ILSAAASSFLLFGMALVYAQSGDLSFVALGKNLGDGMLNEPLLLAGFGLMIVGLGFKL
                     SLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAIRVVLAII
                     AFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQTGEMSMEAVGVYLAGYL
                     FSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILAAVMTVMMLSLAGIPMTLGF
                     IGKFYVLAVGVQAHLWWLVGAVVVGSAIGLYYYLRVAVSLYLHAPEQPGRDAPSNWQY
                     SAGGIVVLISALLVLVLGVWPQPLISIVRLAMPLM"
     gene            complement(2757..4286)
                     /gene="nuoM"
                     /locus_tag="RHX21_001639"
     CDS             complement(2757..4286)
                     /gene="nuoM"
                     /locus_tag="RHX21_001639"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit M"
                     /protein_id="HDV1986839.1"
                     /translation="MLLPWLILIPFIGGFLCWQTERFGVKVPRWIALITMGLTLALSL
                     QLWLQGGYSLTQSAGIPQWQSEFDMPWIPRFGISIHLAIDGLSLLMVVLTGLLGVLAV
                     LCSWKEIEKYQGFFHLNLMWILGGVIGVFLAIDMFLFFFFWEMMLVPMYFLIALWGHK
                     ASDGKTRITAATKFFIYTQASGLVMLIAILALVFVHYNATGVWTFNYEELLNTPMSSG
                     VEYLLMLGFFIAFAVKMPVVPLHGWLPDAHSQAPTAGSVDLAGILLKTAAYGLLRFSL
                     PLFPNASAEFAPIAMWLGVIGIFYGAWMAFAQTDIKRLIAYTSVSHMGFVLIAIYTGS
                     QLAYQGAVIQMIAHGLSAAGLFILCGQLYERIHTRDMRMMGGLWSKMKWLPALSLFFA
                     VATLGMPGTGNFVGEFMILFGSFQVVPVITVISTFGLVFASVYSLAMLHRAYFGKAKS
                     QIASQELPGMSLRELFMILLLVVLLVLLGFYPQPILDTSHSAIGNIQQWFVNSVTTTR
                     P"
     gene            complement(4450..6291)
                     /gene="nuoL"
                     /locus_tag="RHX21_001640"
     CDS             complement(4450..6291)
                     /gene="nuoL"
                     /locus_tag="RHX21_001640"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit L"
                     /protein_id="HDV1986840.1"
                     /translation="MNMLALTIILPLIGFVLLAFSRGRWSENVSAIVGVGSVGLAALV
                     TAFIGVDFFANGEQSYSQPLWTWMSVGDFNIGFNLVLDGLSLTMLSVVTGVGFLIHMY
                     ASWYMRGEEGYSRFFAYTNLFIASMVVLVLADNLLLMYLGWEGVGLCSYLLIGFYYTD
                     PKNGAAAMKAFVVTRVGDVFLAFALFILYNELGTLNFREMVELAPAHFADGNNMLMWA
                     TLMLLGGAVGKSAQLPLQTWLADAMAGPTPVSALIHAATMVTAGVYLIARTHGLFLMT
                     PEVLHLVGIVGAVTLLLAGFAALVQTDIKRVLAYSTMSQIGYMFLALGVQAWDAAIFH
                     LMTHAFFKALLFLASGSVILACHHEQNIFKMGGLRKSIPLVYLCFLVGGAALSALPLV
                     TAGFFSKDEILAGAMANGHINLMVAGLVGAFMTSLYTFRMIFIVFHGKEQIHAHAVKG
                     VTHSLPLIVLLILSTFVGALIVPPLQGVLPQTTELAHGSMLTLEITSGVVAVVGILLA
                     AWLWLGKRTLVTSIANSAPGRLLSTWWYNAWGFDWLYDKVFVKPFLGIAWLLKRDPLN
                     SMMNIPAVLSRFAGKGLLLSENGYLRWYVASMSIGAVVVLALLMVLR"
     gene            complement(6288..6590)
                     /gene="nuoK"
                     /locus_tag="RHX21_001641"
     CDS             complement(6288..6590)
                     /gene="nuoK"
                     /locus_tag="RHX21_001641"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006683663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoK"
                     /protein_id="HDV1986841.1"
                     /translation="MIPLQHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASAL
                     AFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSEMRG"
     gene            complement(6587..7141)
                     /gene="nuoJ"
                     /locus_tag="RHX21_001642"
     CDS             complement(6587..7141)
                     /gene="nuoJ"
                     /locus_tag="RHX21_001642"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit J"
                     /protein_id="HDV1986842.1"
                     /translation="MEFAFYICGLIAILATLRVITHTNPVHALLYLIISLLAISGVFF
                     SLGAYFAGALEIIVYAGAIMVLFVFVVMMLNLGGSEIEQERQWLKPQVWIGPAILSAI
                     MLVVIVYAILGVNDQGIDGTPISAKAVGITLFGPYVLAVELASMLLLAGLVVAFHVGR
                     EERAGEVLSNRKDDSAKRKTEEHA"
     gene            complement(7153..7695)
                     /gene="nuoI"
                     /locus_tag="RHX21_001643"
     CDS             complement(7153..7695)
                     /gene="nuoI"
                     /locus_tag="RHX21_001643"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015959823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoI"
                     /protein_id="HDV1986843.1"
                     /translation="MTLKELLVGFGTQVRSIWMIGLHAFAKRETRMYPEEPVYLPPRY
                     RGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETKDGRWYPEFFRINFSRCIFC
                     GLCEEACPTTAIQLTPDFEMGEYKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDG
                     KDKGEAENEAKPIDVKSLLP"
     gene            complement(7710..8687)
                     /gene="nuoH"
                     /locus_tag="RHX21_001644"
     CDS             complement(7710..8687)
                     /gene="nuoH"
                     /locus_tag="RHX21_001644"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015875065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoH"
                     /protein_id="HDV1986844.1"
                     /translation="MSWISPELIEILLTILKAVVILLVVVTCGAFMSFGERRLLGLFQ
                     NRYGPNRVGWGGSLQLVADMIKMFFKEDWIPKFSDRVIFTLAPMIAFTSLLLAFAIVP
                     VSPGWVVADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFL
                     GLSLMGVVAQAGSFNMTDIVNSQAHVWNVIPQFFGFITFAIAGVAVCHRHPFDQPEAE
                     QELADGYHIEYSGMKFGLFFVGEYIGIVTISALMVTLFFGGWQGPLLPPFIWFALKTA
                     FFMMMFILIRASLPRPRYDQVMSFGWKICLPLTLINLLVTAAVILWQAQ"
     gene            complement(8684..11410)
                     /gene="nuoG"
                     /locus_tag="RHX21_001645"
     CDS             complement(8684..11410)
                     /gene="nuoG"
                     /locus_tag="RHX21_001645"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311194.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoG"
                     /protein_id="HDV1986845.1"
                     /translation="MATIHVDGKEYEVNGADNLLEACLSLGLDIPYFCWHPALGSVGA
                     CRQCAVKQYQNAEDTRGRLVMSCMTPASDGTFISIDDEEAKQFRESVVEWLMTNHPHD
                     CPVCEEGGNCHLQDMTVMTGHSFRRYRFTKRTHRNQDLGPFISHEMNRCIACYRCVRY
                     YKDYADGTDLGVYGAHDNVYFGRPEDGTLESEFSGNLVEICPTGVFTDKTHSERYNRK
                     WDMQFAPSICQQCSIGCNISPGERYGELRRIENRYNGTVNHYFLCDRGRFGYGYVNLK
                     DRPRQPVQRRGDDFITLNAEQAMQGAADILRQSKKVIGIGSPRASVESNFALRELVGE
                     ENFYTGIAHGEQERLQLALKVLREGGIYTPALREIESYDAVLVLGEDVTQTGARVALA
                     VRQAVKGKAREMAAAQKVADWQIAAILNIGQRAKHPLFVTNVDDTRLDDIAAWTYRAP
                     VEDQARLGFAIAHALDNSAPAVDGIEPELQSKIDVIVQALAGAKKPLIISGTNAGSIE
                     VIQAAANVAKALKGRGADVGITMIARSVNSMGLGIMGGGSLEEALTELETGRADAVVV
                     LENDLHRHASATRVNAALAKAPLVMVVDHQRTAIMENAHLVLSAASFAESDGTVINNE
                     GRAQRFFQVYDPAYYDSKTVMLESWRWLHSLHSTLLSREVDWTQLDHVIDAVVAKIPE
                     LAGIKDAAPDATFRIRGQKLAREPHRYSGRTAMRANISVHEPRQPQDIDTMFTFSMEG
                     NNQPTAHRSQVPFAWAPGWNSPQAWNKFQDEVGGKLRFGDPGVRLFETSENGLDYFTS
                     VPARFQPQDGKWRIAPYYHLFGSDELSQRAPVFQSRMPQPYIKLNPADAAKLGVNAGA
                     RVSFSYDGNTVTLPVEIAEGLTAGQVGLPMGMSGIAPVLAGAHLEDLKEAQQ"
     gene            complement(11463..12800)
                     /gene="nuoF"
                     /locus_tag="RHX21_001646"
     CDS             complement(11463..12800)
                     /gene="nuoF"
                     /locus_tag="RHX21_001646"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HDV1986846.1"
                     /translation="MKNIIRTPETHPLTWRLRDDKQPVWLDEYRSKNGYEGARKALTG
                     LSPDEIVNQVKDAGLKGRGGAGFSTGLKWSLMPKDESMNIRYLLCNADEMEPGTYKDR
                     LLMEQLPHLLVEGMLISAFALKAYRGYIFLRGEYIEAAVNLRRAIAEATEAGLLGKNI
                     MGTGFDFELFVHTGAGRYICGEETALINSLEGRRANPRSKPPFPATSGVWGKPTCVNN
                     VETLCNVPAILANGVEWYQNISKSKDAGTKLMGFSGRVKNPGLWELPFGTTAREILED
                     YAGGMRDGLKFKAWQPGGAGTDFLTEAHLDLPMEFESIGKAGSRLGTALAMAVDHEIN
                     MVSLVRNLEEFFARESCGWCTPCRDGLPWSVKILRALERGEGQPGDIETLEQLCRFLG
                     PGKTFCAHAPGAVEPLQSAIKYFREEFEAGIKQPFSNTHLINGIQPNLLKERW"
     gene            complement(12797..13297)
                     /gene="nuoE"
                     /locus_tag="RHX21_001647"
     CDS             complement(12797..13297)
                     /gene="nuoE"
                     /locus_tag="RHX21_001647"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoE"
                     /protein_id="HDV1986847.1"
                     /translation="MHENQQPQTEAFELSAAEREAIEHEMHHYEDPRAASIEALKIVQ
                     KQRGWVPDGAIHAIADVLGIPASDVEGVATFYSQIFRQPVGRHVIRYCDSVVCHINGY
                     QGIQAALEKKLNIKPGQTTFDGRFTLLPTCCLGNCDKGPNMMIDEDTHAHLTPEAIPE
                     LLERYK"
     gene            complement(13300..15102)
                     /gene="nuoC"
                     /locus_tag="RHX21_001648"
     CDS             complement(13300..15102)
                     /gene="nuoC"
                     /locus_tag="RHX21_001648"
                     /EC_number="1.6.5.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit C/D"
                     /protein_id="HDV1986848.1"
                     /translation="MVNNMTDLTAQEPAWQTRDHLDDPVIGELRNRFGPDAFTVQATR
                     TGVPVVWIKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHREGLPAADFSVFYHL
                     ISIDRNRDIMLKVALAENDLHVPTFTKLFPNANWYERETWDLFGITFDGHPNLRRIMM
                     PQTWKGHPLRKDYPARATEFSPFELTKAKQDLEMEALTFKPEEWGMKRGTENEDFMFL
                     NLGPNHPSAHGAFRIVLQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIE
                     YLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMT
                     PVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLDWMPKRLA
                     SYEKAALQNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKARPYSGYENF
                     DFEIPVGGGVSDCYTRVMLKVEELRQSLRILEQCLNNMPEGPFKADHPLTTPPPKERT
                     LQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSY
                     AHLQQIPAAIRGSLVSDLIVYLGSIDFVMSDVDR"
     gene            complement(15196..15858)
                     /gene="nuoB"
                     /locus_tag="RHX21_001649"
     CDS             complement(15196..15858)
                     /gene="nuoB"
                     /locus_tag="RHX21_001649"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoB"
                     /protein_id="HDV1986849.1"
                     /translation="MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEVNKNVFMGKLND
                     MVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADLMVVAGTC
                     FTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPP
                     RPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQSERERKRGERIAVTNLRTPD
                     EI"
     gene            complement(15874..16317)
                     /gene="nuoA"
                     /locus_tag="RHX21_001650"
     CDS             complement(15874..16317)
                     /gene="nuoA"
                     /locus_tag="RHX21_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoA"
                     /protein_id="HDV1986850.1"
                     /translation="MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARAR
                     SKNVPFESGIDSVGSARLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVE
                     AAIFIFVLLAGLVYLVRIGALDWTPARSRRERMNPETNSIANRQR"
     gene            complement(16949..17887)
                     /gene="lrhA"
                     /locus_tag="RHX21_001651"
     CDS             complement(16949..17887)
                     /gene="lrhA"
                     /locus_tag="RHX21_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LrhA"
                     /protein_id="HDV1986851.1"
                     /translation="MISANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQ
                     QMQRLEQLVGKELFARHGRNKLLTEHGIQLLGYARKILRFNDEACSSLMFSNLQGVLT
                     IGASDESADTILPFLLNRVSSVYPKLALDVRVKRNAYMAEMLESQEVDLMVTTHRPSA
                     FKALNLRTSPTHWYCAAEYVLQKGEPIPLVLLDDPSPFRDMVLATLNKADIPWRLAYV
                     ASTLPAVRAAVKAGLGVTARPVEMMSPDLRVLSGVDGLPPLPDTEYLLCYDPSSNNEL
                     AQVIYQAMESYHNPWQYSPISAPEGDDSLLIERDIE"
     gene            18807..20024
                     /gene="alaA"
                     /locus_tag="RHX21_001652"
     CDS             18807..20024
                     /gene="alaA"
                     /locus_tag="RHX21_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine transaminase AlaA"
                     /protein_id="HDV1986852.1"
                     /translation="MSPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPA
                     PFGFDAPDEILVDVIRNLPTAQGYCDSKGLYSARKAIMQHYQARGMRDVTVEDIYIGN
                     GVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDD
                     IRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQHNLIIFADEIYDKILYDDA
                     EHHSIAPLAPDLLTITFNGLSKTYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRL
                     CANVPAQHAIQTALGGYQSISEFITPGGRLYEQRNRAWELINDIPGVSCVKPRGALYM
                     FPKIDAKRFNIHDDQKMVLDFLLQEKVLLVQGTAFNWPWPDHFRIVTLPRVDDIELSL
                     SKFARFLSGYHQL"
     gene            20108..20707
                     /gene="yfbR"
                     /locus_tag="RHX21_001653"
     CDS             20108..20707
                     /gene="yfbR"
                     /locus_tag="RHX21_001653"
                     /EC_number="3.1.3.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-deoxynucleotidase"
                     /protein_id="HDV1986853.1"
                     /translation="MKQSHFFAHLSRLKLINRWPLMRNVRTENVSEHSLQVAMVAHAL
                     AAIKNRKFGGNVNAERIALLAMYHDASEVLTGDLPTPVKYFNSQIAQEYKAIEKIAQQ
                     KLVDMVPEELRDIFAPLIDEHAYSDEEKSLVKQADALCAYLKCLEELAAGNNEFLLAK
                     TRLEATLEARRSQEMDYFMEVFVPSFHLSLDEISQDSPL"
     gene            complement(20766..22598)
                     /locus_tag="RHX21_001654"
     CDS             complement(20766..22598)
                     /locus_tag="RHX21_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HDV1986854.1"
                     /translation="MNGELIWVLSLLAVAIVLFATGRVRMDAVALFVIVAFALSGTLT
                     VPEVFSGFSDPNVVLIAALFIIGDGLVRTGVATVMGTWLVKVAGNSEIKMLVLLMLTV
                     AGLGAFMSSTGVVAIFIPVVLSVAMRMQTSPSRLMMPLSFAGLISGMMTLVATPPNLV
                     VNSELLREGYHGFSFFSVTPIGLVVLVLGILYMLVMRFMLKGDTQTPQREGWTRRTFR
                     DLIREYRLTGRARRLAIRPGSPMIGQRLDDLKLRERYGANVIGVERWRRFRRVIVNVN
                     GVSEFRARDVLLIDMSAADVDLRQFCSEQLLEPMVLRGEYFSDQALDVGMAEISLIPE
                     SELIGKSVREIGFRTRYGLNVVGLKRNGVALEGSLADEPLLLGDIILVVGNWKLIGML
                     AKQGRDFVALNLPEEVSEASPAHSQAPHAIFCLVLMVALMLTDEIPNPVAAIIACLLM
                     GKFRCIDAESAYKSIHWPSIILIVGMMPFAVALQKTGGVALAVKGLMDIGGGYGPHMM
                     LGCLFVLSAVIGLFISNTATAVLMAPIALAAAKTMGVSPYPFAMVVAMAASAAFMTPV
                     SSPVNTLVLGPGNYSFSDFVKLGVPFTIIVMAVCVVMIPMLFPF"
     gene            complement(22685..23335)
                     /gene="hxpA"
                     /locus_tag="RHX21_001655"
     CDS             complement(22685..23335)
                     /gene="hxpA"
                     /locus_tag="RHX21_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexitol phosphatase HxpA"
                     /protein_id="HDV1986855.1"
                     /translation="MRCKGFLFDLDGTLVDSLPAVERAWSNWARRHGLAPEEVLAFIH
                     GKQAITSLRHFMAGKSEADIAAEFTRLEQIEATETEGITALPGAIALLNHLNKAGIPW
                     AIVTSGSMPVARARHKIAGLPAPEVFVTAERVKRGKPEPDAYLLGAQLLGLAPQECVV
                     VEDAPAGVLSGLAAGCHVIAVNAPADTPRLNEVDLVLHSLEQITVTKQPNGDVIIQ"
     gene            complement(23346..23840)
                     /locus_tag="RHX21_001656"
     CDS             complement(23346..23840)
                     /locus_tag="RHX21_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007371080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HDV1986856.1"
                     /translation="MEMTNAQRLILSNQYKMMTMLDPANAERYRRLQTIIERGYGLQM
                     RELDREFGELKEETCRTIIDIMEMYHALHVSWSNLQDQQSIDERRVTFLGFDAATEAR
                     YLGYVRFMVNVEGRYTHFDAGTHGFNAQTPMWEKYQRMLNVWHACPRQYHLSANEINQ
                     IINA"
     gene            complement(23923..24378)
                     /locus_tag="RHX21_001657"
     CDS             complement(23923..24378)
                     /locus_tag="RHX21_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF412 domain-containing protein"
                     /protein_id="HDV1986857.1"
                     /translation="MSTPDNRSVNFFSLFRRGQHYSKTWPLEKRLAPVFVENRVIKMT
                     RYAIRFMPPIAVFTLCWQIALGGQLGPAVATALFALSLPMQGLWWLGKRSVTPLPPAI
                     LNWFYEVRGKLQESGQVLAPVEGKPDYQALADTLKRAFKQLDKTFLDDL"
     gene            24716..25918
                     /gene="ackA"
                     /locus_tag="RHX21_001658"
     CDS             24716..25918
                     /gene="ackA"
                     /locus_tag="RHX21_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HDV1986858.1"
                     /translation="MSSKLVLVLNCGSSSLKFAIIDAVNGEEYLSGLAECFHLPEARI
                     KWKMDGNKQEAALGAGAAHSEALNFIVNTILAQKPELSAQLTAIGHRIVHGGEKYTSS
                     VVIDESVIQGIKDAASFAPLHNPAHLIGIEEALKSFPQLKDKNVAVFDTAFHQTMPEE
                     SYLYALPYNLYKEHGIRRYGAHGTSHFYVTQEAAKMLNKPVEELNIITCHLGNGGSVS
                     AIRNGKCVDTSMGLTPLEGLVMGTRSGDIDPAIIFHLHDTLGMSVDAINKLLTKESGL
                     LGLTEVTSDCRYVEDNYATKEDAKRAMDVYCHRLAKYIGAYTALMDGRLDAVVFTGGI
                     GENAAMVRELSLGKLGVLGFEVDHERNLAARFGKSGFINKEGTRPAVVIPTNEELVIA
                     QDASRLTA"
     gene            25993..28137
                     /gene="pta"
                     /locus_tag="RHX21_001659"
     CDS             25993..28137
                     /gene="pta"
                     /locus_tag="RHX21_001659"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HDV1986859.1"
                     /translation="MSRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPR
                     TGGDAPDQTTTIVRANSSTTTAAEPLKMSYVEGLLSSNQKDVLMEEIVANYHANTKDA
                     EVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLKERIELTRNSFG
                     GAKNTNITGVIVNKLNAPVDEQGRTRPDLSEIFDDSSKAKVNNVDPAKLQESSPLPVL
                     GAVPWSFDLIATRAIDMARHLNATIINEGDINTRRVKSVTFCARSIPHMLEHFRAGSL
                     LVTSADRPDVLVAACLAAMNGVEIGALLLTGGYEMDARISKLCERAFATGLPVFMVNT
                     NTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYINADWIDSLTATSERSRRLSPPAF
                     RYQLTELARKAGKRIVLPEGDEPRTVKAAAICAERGIATCVLLGNPAEINRVAASQGV
                     ELGAGIEIVDPEVVRESYVGRLVELRKNKGMTETVAREQLEDNVVLGTLMLEQDEVDG
                     LVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDPTAEQL
                     AEIAIQSADSAAAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGP
                     LQYDAAVMADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQG
                     MRKPVNDLSRGALVDDIVYTIALTAIQSAQQQ"
     gene            28327..29847
                     /gene="yfcC"
                     /locus_tag="RHX21_001660"
     CDS             28327..29847
                     /gene="yfcC"
                     /locus_tag="RHX21_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HDV1986860.1"
                     /translation="MSAITESKPTRRWAMPDTLVIIFFVAILTSLATWVVPVGMFDSQ
                     EVQYQVDGQTKTRKVVDPHSFRILTNEAGEPEYHRVQLFTTGDERPGLMNFPFEGLTS
                     GSKYGTAVGIIMFMLVIGGAFGIVMRTGTIDNGILALIRHTRGNEILFIPALFILFSL
                     GGAVFGMGEEAVAFAIIIAPLMVRLGYDSITTVLVTYIATQIGFASSWMNPFCVVVAQ
                     GIAGVPVLSGSGLRIVVWVIATLIGLIFTMVYASRVKKNPLLSRVHESDRFFREKQAD
                     VEQRPFTFGDWLVLIVLTAVMVWVIWGVIVNAWFIPEIASQFFTMGLVIGIIGVVFRL
                     NGMTVNTMASSFTEGARMMIAPALLVGFAKGILLLVGNGEAGDASVLNTILNSIANAI
                     SGLDNAVAAWFMLLFQAVFNFFVTSGSGQAALTMPLLAPLGDLVGVNRQVTVLAFQFG
                     DGFSHIIYPTSASLMATLGVCRVDFRNWLKVGATLLGLLFIMSSVVVIGAQLMGYH"
     gene            complement(29880..30422)
                     /gene="yfcD"
                     /locus_tag="RHX21_001661"
     CDS             complement(29880..30422)
                     /gene="yfcD"
                     /locus_tag="RHX21_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase YfcD"
                     /protein_id="HDV1986861.1"
                     /translation="MEQRRLASTEWVDIVNEENEVIAQASREQMRAQCLRHRATYIVV
                     HDGMGKILVQRRTETKDFLPGMLDATAGGVVQADEQLLESARREAEEELGIAGVPFAE
                     HGQFYFEDKNCRVWGALFSCVSHGPFALQEDEVSEVCWLTPEEITARCDEFTPDSLKA
                     LALWMKRNAKNEAVETETAE"
     gene            complement(30480..31031)
                     /gene="yfcE"
                     /locus_tag="RHX21_001662"
     CDS             complement(30480..31031)
                     /gene="yfcE"
                     /locus_tag="RHX21_001662"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311211.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HDV1986862.1"
                     /translation="MKLMFASDIHGSLPATERVLELFAQSGAQWLVILGDVLNHGPRN
                     ALPEGYAPAKVAERLNEVAHKVIAVRGNCDSEVDQMLLHFPITAPWQQVLLEKQRLFL
                     THGHLFGPENLPALNQNDVLVYGHTHLPVAEQRGEIFHFNPGSVSIPKGGNPASYGML
                     DNDVLSVIALNDQSIIAQVAINP"
     gene            complement(31087..31731)
                     /gene="yfcF"
                     /locus_tag="RHX21_001663"
     CDS             complement(31087..31731)
                     /gene="yfcF"
                     /locus_tag="RHX21_001663"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione transferase"
                     /protein_id="HDV1986863.1"
                     /translation="MSKPAITLWSDAHFFSPYVLSAWVALQEKGLSFHIKTIDLDSGE
                     HLQPTWQGYGQTRRVPLLQIDDFELSESSAIAEYLEDRFAPPTWERIYPLDLENRARA
                     RQIQAWLRSDLMPIREERPTDVVFAGAKKAPLTAEGKASAEKLFAMAEHLLALGQPNL
                     FGEWCIADTDLALMINRLVLHGDEVPERLVDYATFQWQRASVQRFIALSAKQSG"
     gene            31867..32514
                     /gene="yfcG"
                     /locus_tag="RHX21_001664"
     CDS             31867..32514
                     /gene="yfcG"
                     /locus_tag="RHX21_001664"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GSH-dependent disulfide bond oxidoreductase"
                     /protein_id="HDV1986864.1"
                     /translation="MIDLYFAPTPNGHKITLFLEEAELDYRLIKVDLGKGGQFRPEFL
                     RISPNNKIPAIVDHSPADGGEPLSLFESGAILLYLAEKTGLFLSHETRERAATLQWLF
                     WQVGGLGPMLGQNHHFNHAAPQTIPYAIERYQVETQRLYHVLNKRLENSPWLGGENYS
                     IADIACWPWVNAWTRQRIDLAMYPAVKNWHERIRSRPATGQALLKAQLGDERSDS"
     gene            32571..32933
                     /gene="folX"
                     /locus_tag="RHX21_001665"
     CDS             32571..32933
                     /gene="folX"
                     /locus_tag="RHX21_001665"
                     /EC_number="5.1.99.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin triphosphate 2'-epimerase"
                     /protein_id="HDV1986865.1"
                     /translation="MAQPAAIIRIKNLRLRTFIGIKEEEINNRQDIVINVTIHYPADK
                     ARTSEDINDALNYRTVTKNIIQHVENNRFSLLEKLTQDVLDIAREHHWVTYAEVEIDK
                     LHALRYADSVSMTLSWQR"
     gene            32954..33847
                     /locus_tag="RHX21_001666"
     CDS             32954..33847
                     /locus_tag="RHX21_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01777 family oxidoreductase"
                     /protein_id="HDV1986866.1"
                     /translation="MNIVITGGTGLIGRHLIPRLLELGHQITVMTRNPQKASSVLGPR
                     VTLWQGLADQSNLNGVDAVINLAGEPIADKRWTHEQKERLCQSRWNITQKLVDLINAS
                     DTPPSVLISGSATGYYGDLGEVVVTEEEPPHNEFTHKLCTRWEEIACRAQSDKTRVCL
                     LRTGVVLAPDGGILGKMLPPFRLGLGGPIGSGRQYLAWIHIDDMVNGILWLLDNELRG
                     PFNMVSPYPIRNEQFAHALGHALHRPAILRVPATAIRLLMGESSVLVLGGQRALPKRL
                     EEAGFAFRWYDLEEALADVVR"
     gene            complement(33895..34785)
                     /gene="rpnB"
                     /locus_tag="RHX21_001667"
     CDS             complement(33895..34785)
                     /gene="rpnB"
                     /locus_tag="RHX21_001667"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-promoting nuclease RpnB"
                     /protein_id="HDV1986867.1"
                     /translation="MTISTTSTPHDAVFKSFLRHPDTARDFIDIHLTAPLRKLCDLTT
                     LKLEPNSFIDEDLRQYYSDLLWSVKTQEGVGYIYVVIEHQSKPEELMAFRMMRYSIAA
                     MQNHLDAGYKELPLVIPMLFYHGCRSPYPYSLCWLDEFAEPAIARKIYSSAFPLVDIT
                     VVPDDEIMQHRKMALLELIQKHIRQRDLLGLVDQIVSLLVTGNTNDRQLKALFNYVLQ
                     TGDAQRFRAFIGEITERAPQEKEKLMTIADRLREEGAMQGKHEEALRIAQEMLEKGFD
                     HEVILTLTRLSPDDLIAQSH"
     gene            complement(34982..35755)
                     /gene="hisP"
                     /locus_tag="RHX21_001668"
     CDS             complement(34982..35755)
                     /gene="hisP"
                     /locus_tag="RHX21_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter ATP-binding protein
                     HisP"
                     /protein_id="HDV1986868.1"
                     /translation="MSENKLNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGK
                     STFLRCINFLEKPSEGAIVVNGQTINLVRDKDGQLKVADKNQLRLLRTRLTMVFQHFN
                     LWSHMTVLENVMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQGKYPVHLSGGQQQR
                     VSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHV
                     STHVIFLHQGKIEEEGAPEQLFGNPQSPRLQQFLKGSLK"
     gene            complement(35763..36479)
                     /locus_tag="RHX21_001669"
     CDS             complement(35763..36479)
                     /locus_tag="RHX21_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV1986869.1"
                     /translation="MIEILHEYWKPLLWTDGYRFTGVAITLWLLILSVVIGGVLALFL
                     AIGRVSSNKYIQFPIWLFTYIFRGTPLYVQLLVFYSGMYTLEIVKGTEFLNAFFRSGL
                     NCTVLALTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGFSTFKMYRCIILPSALRIAL
                     PAYSNEVILMLHSTALAFTATVPDLLKIARDINAATYQPFTAFGIAAVLYLIISYVLI
                     SLFRRAEKRWLQHVKPSSTH"
     gene            complement(36476..37162)
                     /gene="hisQ"
                     /locus_tag="RHX21_001670"
     CDS             complement(36476..37162)
                     /gene="hisQ"
                     /locus_tag="RHX21_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012124147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter permease HisQ"
                     /protein_id="HDV1986870.1"
                     /translation="MLYGFSGVILQGALVTLELAISSVVLAVIIGLIGAGGKLSQNRL
                     SGLIFEGYTTLIRGVPDLVLMLLIFYGLQIALNTVTEAMGVGQIDIDPMVAGIITLGF
                     IYGAYFTETFRGAFMAVPKGHIEAATAFGFTRGQVFRRIMFPAMMRYALPGIGNNWQV
                     ILKSTALVSLLGLEDVVKATQLAGKSTWEPFYFAIVCGVIYLVFTTVSNGVLLFLERR
                     YSVGVKRADL"
     gene            complement(37252..38034)
                     /gene="hisJ"
                     /locus_tag="RHX21_001671"
     CDS             complement(37252..38034)
                     /gene="hisJ"
                     /locus_tag="RHX21_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter substrate-binding
                     protein HisJ"
                     /protein_id="HDV1986871.1"
                     /translation="MKKLVLSLSLVLAFSSATAAFAAIPQNIRIGTDPTYAPFESKNS
                     QGELVGFDIDLAKELCKRINTQCTFVENPLDALIPSLKAKKIDAIMSSLSITEKRQQE
                     IAFTDKLYAADSRLVVAKNSDIQPTVESLKGKRVGVLQGTTQETFGNEHWAPKGIEIV
                     SYQGQDNIYSDLTAGRIDAAFQDEVAASEGFLKQPVGKDYKFGGPSVKDEKLFGVGTG
                     MGLRKEDNELREALNKAFAEMRADGTYEKLAKKYFDFDVYGG"
     gene            complement(38255..39037)
                     /gene="argT"
                     /locus_tag="RHX21_001672"
     CDS             complement(38255..39037)
                     /gene="argT"
                     /locus_tag="RHX21_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine/arginine/ornithine ABC transporter
                     substrate-binding protein ArgT"
                     /protein_id="HDV1986872.1"
                     /translation="MKKSILALSLLVGLSAAASSYAALPETVRIGTDTTYAPFSSKDA
                     KGDFVGFDIDLGNEMCKRMQVKCTWVASDFDALIPSLKAKKIDAIISSLSITDKRQQE
                     IAFSDKLYAADSRLIAAKGSPIQPTLDSLKGKHVGVLQGSTQEAYANETWRSKGVDVV
                     AYANQDLVYSDLAAGRLDAALQDEVAASEGFLKQPAGKDFAFAGSSVKDKKYFGDGTG
                     VGLRKDDTELTAAFNKALGELRQDGTYDKMAKKYFDFNVYGD"
     gene            complement(39303..39872)
                     /gene="ubiX"
                     /locus_tag="RHX21_001673"
     CDS             complement(39303..39872)
                     /gene="ubiX"
                     /locus_tag="RHX21_001673"
                     /EC_number="2.5.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin prenyltransferase UbiX"
                     /protein_id="HDV1986873.1"
                     /translation="MKRLIVGISGASGAIYGVRLLQVLRDVTDIETHLVMSQAARQTL
                     SLETDFSLREVQALADVTHDARDIAASISSGSFQTLGMVILPCSIKTLSGIVHSYTDG
                     LLTRAADVVLKERRPLVLCVRETPLHLGHLRLMTQAAEIGAVIMPPVPAFYHRPQSLD
                     DVINQTVNRVLDQFAITLPEDLFARWQGA"
     gene            complement(39967..41484)
                     /gene="purF"
                     /locus_tag="RHX21_001674"
     CDS             complement(39967..41484)
                     /gene="purF"
                     /locus_tag="RHX21_001674"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006820991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HDV1986874.1"
                     /translation="MCGIVGIAGVMPVNQSIYDALTVLQHRGQDAAGIITIDANNCFR
                     LRKANGLVSDVFEARHMQRLQGNMGIGHVRYPTAGSSSASEAQPFYVNSPYGITLAHN
                     GNLTNAHELRKKLFEEKRRHINTTSDSEILLNIFASELDNFRHYPLEADNIFAAIAAT
                     NRLIRGAYACVAMIIGHGMVAFRDPNGIRPLVLGKRDIDENRTEYMVASESVALDTLG
                     FDFLRDVAPGEAIYITEEGQLFTRQCADNPVSNPCLFEYVYFARPDSFIDKISVYSAR
                     VNMGTKLGEKIAREWEDLDIDVVIPIPETSCDIALEIARILGKPYRQGFVKNRYVGRT
                     FIMPGQQLRRKSVRRKLNANRAEFRDKNVLLVDDSIVRGTTSEQIIEMAREAGAKKVY
                     LASAAPEIRFPNVYGIDMPSATELIAHGREVDEIRQIIGADGLIFQDLNDLIDAVRAE
                     NPDIQQFECSVFNGVYVTKDVDQGYLDFLDTLRNDDAKAVQRQNEVENLEMHNEG"
     gene            complement(41521..42009)
                     /gene="cvpA"
                     /locus_tag="RHX21_001675"
     CDS             complement(41521..42009)
                     /gene="cvpA"
                     /locus_tag="RHX21_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin V production protein"
                     /protein_id="HDV1986875.1"
                     /translation="MVWIDYAIIAVIAFSSLVSLIRGFVREALSLVTWGCAFFVASHY
                     YTYLSVWFTGFEDELVRNGIAIAVLFIATLIVGAIVNFVIGQLVEKTGLSGTDRVLGV
                     CFGALRGVLIVAAILFFLDSFTGVSKSEDWSKSQLIPQFSFIIRWFFDYLQSSSSFLP
                     RA"
BASE COUNT        10603 a        11420 c        10536 g         9660 t
ORIGIN      
        1 atccttttgt tatattattt ctgatttcac tccctctgat tatttttacc aaccctgggt
       61 cactgcatta tcgccaacgc cccgacacgt cagtcctgag caattagaaa aaacagttcg
      121 ttatcttaca caaactgtgc atccacgtaa tgccgacaat attgataatc tgaataggtc
      181 cgtagagtat ataaaagagt tctttgtcag tagcggtgcc agagttaccg cgcagggcgt
      241 ccccgattgg ctattacgac tctgcgcctg gtagccagga ttacccttac ccgcaatgtc
      301 ctggctttat cccgatcggg gggactttat tgcctggtcg gcagaataca ggatatcaac
      361 gccgttcgtc aggtaaaaac ggcattgtta tcatcccggg atttatctgt ttattctatg
      421 aatgccccat ggtttattcc cggtattgat ttctctgacc acctgaatta ttggcaacac
      481 gatattcccg ccgtaatgat tactgacacc gctttttatc gtaataaaca ataccacttg
      541 cccggtgata cagcagacag attgaattat cagaaaatgg ctcagatggc gttataacct
      601 tgttacacaa cagtaaataa taaaaatttc tcgaggcggg tccagaaaca gcgacatgta
      661 cattttattt tccctcgtct gttttaagat gcgaaacata aaattcaatg gaggaaaaat
      721 aaatgggaat gattggttat tttgcagaaa ttgactcaga aaagattaac caactgcttg
      781 agtctactga aaaacctttg atggataata tacatgacac gctttcagga ttacgccgac
      841 tggatattga taaacgctgg gattttttac actttgggct gacaggcacc tctgcttttg
      901 atcccgcgaa gaatgatccg ctgagtcgtg ccgtgcttgg tgaacacagc ctcgaagatg
      961 gcatagatgg cttcctggga ttgacctgga atcaggagtt agccgcgaca atcgaccgac
     1021 tggaatcact ggatcgaagt gagctgcgta aacagttttc cattaagcga ctcaatgaaa
     1081 tggagattta tccgggagtg accttttcag aagagttaga ggggcaactc tttgcttcga
     1141 tcatgcttga tatggaaaag ctgattagcg cgtatcgacg tatgctgcga caagggaatc
     1201 atgcgctgac ggttattgtt gggtgatggt gtcagggcac caaaaaaaac cgccgaacat
     1261 gtcggcggct ttctgactta caaactgata gcttacatca gcggcattgc taaccgcaca
     1321 atgctaatca gcggttgtgg ccatacaccc agcaccagta ccaacagtgc agagatcagc
     1381 accacgatac cgcctgcgct gtactgccag tttgacggtg catcgcgacc cggttgttcc
     1441 ggggcgtgca ggtacaggct caccgccacg cgcaggtagt agtaaaggcc gattgccgaa
     1501 ccgacaacca cggcgcccac cagccaccac aagtgtgcct ggacaccgac cgccagcacg
     1561 tagaacttac caataaagcc cagcgtcatc ggaataccgg ccagagacag catcatcacc
     1621 gtcatcaccg ccgcgaggat cgggcgatgc cagaacagac cgcggtaaga gaacagggaa
     1681 tcagcatccg ggccacggta cgggctggac atcaggctga ccacgccgaa cgcgccgagg
     1741 ctgctgaaca gataaccggc caggtaaact cctaccgctt ccatcgacat ctcgcccgtt
     1801 tgcagcgcaa tcagcgccac cagcagatag ccgaggtgag agatagatga gtaaccgagc
     1861 agacgtttga tattggtctg gctcagcgcc atcaggttac cgaagatgat agaggcaaag
     1921 gcgataatcg ccagcactac ccgaatcgct tcgctgtcac ccaccggtgc gtagaggaac
     1981 agacgcatca ccacaccgaa gatagcgatt ttgctcgccg tcgccaggaa agtggaaacc
     2041 ggcgcaggcg cgccctggta tacgtctggc gtccacaggt ggaacggcac cagagagagt
     2101 ttgaagccga ggccaacaat catcagtccg aaacctgcca gcaacagcgg ctcgttgagc
     2161 ataccgtcgc cgaggttttt acccagcgcg acaaacgaca ggtcgccaga ctgtgcatac
     2221 accagcgcca taccaaacag caggaaagaa gacgctgcgg cagaaaggat ggtgtatttg
     2281 atactggctt ccagcgaacg tttctggcgg aaagcgtaac cgaccaggcc aaacagcggc
     2341 aaagagatca gttcaatacc gaggaacaaa gacgccagat ggttggcatt cgccagcagg
     2401 atcccgccca gcgcggcaat taacaccaac aggtagaact catccttgtt gtcgttatag
     2461 ccttcaagcc acgggtaggc gaaagtacag gtggcgaggc tcgccaacaa taccagcccg
     2521 gtgtaaagca tggcgaaacc atcaacgcgc atcagcggcg taacgtccat agcgcccgcc
     2581 tggccgacaa accagagcga aaccagcgcc gcgttaagcc caataaccga gagcgtagcg
     2641 ttgaggaaat gattgcgtcg ccacgcaatg gagagcatca caaccaccac cgtcaagccg
     2701 acgatcagca acggtagcag tgcgatcagg ttttgtggag ttattgtcat ggcgatttac
     2761 ggccttgtag tagtaacgga attaacaaac cactgctgga tattgccaat cgcggagtgc
     2821 gaggtatcca gaatcggctg cggatagaag cccagcagta ccagcagcac caccagcaac
     2881 aggatcataa acagctcacg cagcgacatc cctggcagtt cctggctggc aatctggctt
     2941 ttcgctttac cgaagtaagc gcgatgcaac atcgccagcg aataaacaga tgcaaagacc
     3001 agcccaaagg tagagataac ggtaatcacc gggacaacct ggaagctgcc gaacagaatc
     3061 ataaattcgc cgacgaagtt accggtgcca ggcatcccaa gcgttgccac cgcaaagaac
     3121 agcgacagtg ctggcagcca tttcatcttg ctccacagac cgcccatcat gcgcatgtcg
     3181 cgggtatgga tacgttcata aagctgacca caaagaataa acagacccgc cgccgacaag
     3241 ccgtgcgcaa tcatctggat taccgcgccc tggtaggcca actggctgcc ggtgtagata
     3301 gcaatcagca cgaagcccat gtgggaaacc gaggtgtagg cgatcagacg tttgatatcg
     3361 gtctgggcga aagccatcca cgcaccgtag aagatgccga taacccccag ccacatagcg
     3421 attggcgcaa actctgccga tgcgttcggg aacagcggca gggagaaacg cagcaaaccg
     3481 taagcggcag ttttcagcaa gatccccgcg aggtcaacgg aaccggcggt cggagcctga
     3541 gagtgcgcat ccggtagcca gccatgcagc ggaaccaccg gcattttgac tgcgaaggcg
     3601 atgaagaagc ccagcattaa caggtattcc acaccactgg acattggcgt attcagcagc
     3661 tcttcatagt tgaaggtcca gacgccggtc gcattgtagt gaacaaaaac cagcgccagg
     3721 atggcaatca acatcaccag gccactcgcc tgggtgtaaa tgaagaactt ggttgccgcc
     3781 gtgatacgcg ttttaccgtc agaggcttta tgcccccaca gtgcgatcag gaagtacatc
     3841 ggcaccagca tcatttccca gaagaagaag aacaggaaca tgtcgatggc aaggaacacg
     3901 ccgataacgc cgcccaggat ccacatcagg ttgaggtgga agaagccctg atatttttcg
     3961 atctctttcc acgaacatag taccgccagc acaccgagca gaccggtcag cacgaccatc
     4021 agcagcgaca gcccgtcaat ggcgagatga atagagatac caaaacgcgg gatccacggc
     4081 atgtcgaatt cagactgcca ctgcggaatt ccggcggatt gcgtcagtga ataaccgccc
     4141 tgcaaccaca gttgcagcga cagcgccagc gtcaatccca tggtgatcag cgcgatccag
     4201 cgtggcacct tgacgccaaa gcgttcggtc tgccagcaca ggaagccgcc aataaaggga
     4261 attaatatta gccagggtag taacatggcg atctttattc cttgtaaaag tcccgtcagg
     4321 accggatttt caacgaattc tcacgacaga aaattctctt cggactgggg gtagtgtcgg
     4381 atgcaccgcg aaggcggctt atccgaccta cgttcttata tgcccagggg caatcccaca
     4441 atccttaact caacgcagta ccatcaacag tgccagcacc acgaccgcac cgatgctcat
     4501 ggatgccaca taccagcgca gatagccgtt ctcacttaac agcagacctt tacctgcaaa
     4561 gcgggaaaga accgccggga tgttcatcat tgagttcagc ggatcgcgtt tcagcaacca
     4621 ggcaataccc aggaacggct tgacgaacac tttgtcgtac agccagtcaa agccccaggc
     4681 gttgtaccac caggtactca gcaggcggcc cggcgcactg ttggcgatgg aggtcaccag
     4741 agtacgttta cccagccaca gccaggctgc cagcagaatg ccgaccaccg cgaccacgcc
     4801 agaggtaatt tccagggtca acatgctgcc gtgcgccagt tccgtcgttt gcggaagcac
     4861 gccctgcagc ggcggtacaa tcagtgcgcc aacgaaggtg gaaaggatca gcagcacaat
     4921 cagcggcagg ctgtgagtta cccctttcac ggcgtgagcg tgaatttgtt cttttccgtg
     4981 gaagacgatg aaaatcatac ggaaggtgta gagcgaggtc ataaacgcac cgaccagacc
     5041 tgccaccatc agattgatat gaccattcgc catcgcaccc gcgaggatct catccttact
     5101 gaagaagccc gcagtgacca gcggcagtgc cgacagtgct gcgccgccca ccaggaagca
     5161 gagataaacc agcggaatag atttacgcag accgcccatc ttgaagatgt tctgttcgtg
     5221 atggcaggcc agaatgacgg aaccggatgc caggaacagc agcgctttaa agaacgcgtg
     5281 agtcatcaag tggaaaatcg ccgcatccca tgcctgcacg ccaagcgcga ggaacatgta
     5341 gccaatctgg ctcatggtag agtaagcgag aacacgtttg atgtcggtct gtaccagcgc
     5401 ggcaaaaccg gccagcagca gcgtaaccgc cccgacaata cccaccagat gcagaacttc
     5461 cggcgtcatc aggaacaggc cgtgggtacg ggcgatcagg tagacacccg cggttaccat
     5521 cgttgcggcg tggatcagcg cggagacagg cgtcgggcca gccatcgcat cggcaagcca
     5581 tgtctgcaac ggcaactgcg cagatttacc gaccgcaccg cccagcagca tcagcgtcgc
     5641 ccacatcagc atgttattgc cgtcagcaaa gtgcgctggt gccagttcca ccatttcgcg
     5701 gaagttcagg gtgcccagtt cgttgtaaag aatgaacagt gcgaaagcga ggaacacgtc
     5761 acccacacgg gtcacgacga acgctttcat tgccgctgcg ccattcttcg gatcggtgta
     5821 atagaaaccg atcagcagat aggagcacag gcccacgcct tcccagccga ggtacatcag
     5881 cagcaggttg tcggcaagca ccagaactac catgctggcg atgaacaggt tggtgtaggc
     5941 gaagaagcga gagtagccct cttcaccgcg catgtaccag gaggcgtaca tgtgaataag
     6001 gaaacccaca ccagtgacca ccgagagcat ggtcagcgac aggccgtcca gcaccagatt
     6061 gaaaccgatg ttaaagtcgc ctaccgacat ccacgtccac agcggctggc tgtatgactg
     6121 ctcgccgtta gcgaagaaat caacgccgat aaaggcggtt accagcgccg ccaggcccac
     6181 agagccaacg ccgacgatcg ccgaaacgtt ttcagaccag cgcccacggg agaacgccag
     6241 caggacgaag ccaatcaatg gcaaaataat ggttaaggca agcatgttca tccgcgcatc
     6301 tcacttactg aatcgatgtt caggttctgg cgacgacggt gaagttgcag cagcagcgca
     6361 aggccgatac tcgcttctgc cgccgcgagg ctgatggcga gaatgtacat cacctgaccg
     6421 tcggtctgac cccagtagct tccggcgacc acaaaggcca gcgcggaggc gttaatcatg
     6481 atttccagac caatcagcat aaacagcaga ttgcgacgga taaccagacc ggttaagcca
     6541 agaacgaata agattgccgc gaggatcagt ccatgttgta aggggatcat gcgtgctcct
     6601 ccgtttttct tttcgcgctg tcgtctttac gattgctcag cacttcaccc gcacgctctt
     6661 cacgaccgac gtggaaggcc acaaccagac ccgcgagcag cagcatagaa gccagttcca
     6721 ccgccagtac gtaaggcccg aacagcgtaa tacccactgc tttagcactg attggcgtac
     6781 cgtcgatacc ctgatcatta acaccaagga tggcgtaaac aatcaccacc agcatgatgg
     6841 ccgacaaaat tgccggacca atccacacct gcggtttcag ccactggcgt tcctgttcga
     6901 tttctgaacc gcccaggttg agcatcatca ccacgaacac gaacagcacc ataatggcac
     6961 ccgcgtagac gataatttcc agcgcaccgg cgaagtaagc gcccagtgag aagaacaccc
     7021 cggaaatcgc cagcagcgaa ataatcaggt acagcagtgc gtgtaccgga ttggtatggg
     7081 tgatcactcg caaggtcgca agtatggcta tcaggccaca gatataaaaa gcgaactcca
     7141 ttgcccctct ccttacggta acaggctctt gacgtcgata ggcttggctt cgttctctgc
     7201 ttcgccctta tctttgccgt cgattgccat acctgccatc cggtagaagt tatattccgg
     7261 gtatttgccc ggaccggaga tcagcagatc ctctttttcg taaaccagat cctggcgctt
     7321 gtattccccc atttcgaaat ccggggttaa ctgaatcgcc gtggtcggac aggcttcttc
     7381 gcacagacca cagaaaatgc agcgtgagaa gttgatgcgg aaaaattccg ggtaccagcg
     7441 accgtctttg gtttctgctt tttgcagcga gatacagccg accgggcagg ctaccgcgca
     7501 gaggttacag gctacgcaac gctcttcgcc gtccgggtcg cgggtcagaa cgatacgacc
     7561 acgataacgg ggcggcagat agaccggctc ttccgggtac attcgcgttt cgcgtttggc
     7621 gaacgcgtgc aggccgatca tccagatact acgaacctgg gtgccgaaac ctactaacaa
     7681 ttcttttaag gtcatggtct tattgcccct tattgcgcct gccagagaat gacagccgcc
     7741 gttaccagca agttgatcag cgtcagcggc aggcagattt tccagccgaa ggacattacc
     7801 tggtcataac gcggacgcgg taacgacgca cgaatcaaaa tgaacatcat cataaagaac
     7861 gcggttttca gcgcgaacca gatgaatggc ggtaacaacg ggccttgcca gccaccgaag
     7921 aacagcgtca ccatcaatgc agagatggtc acaatcccga tgtactcacc cacgaagaac
     7981 agaccgaact tcataccgga atattcaatg tggtaaccat ccgccagttc ctgctcggct
     8041 tccggctggt caaacgggtg acggtgacat accgccacgc ccgcgatggc aaaggtaata
     8101 aaaccaaaga attgcgggat aacgttccac acatgcgcct ggctgttgac gatgtcggtc
     8161 atgttgaatg aaccggcctg cgccaccacg cccatcaggg aaagcccgag gaacacttcg
     8221 tagctcaggg tctgcgcaga agcacgcatc gcacccagca acgagtattt gttgttactt
     8281 gaccagcccg caaacagcac cgcgtaaacc gccagacctg ccatcatcag gaagaacaaa
     8341 atcccgatgt tcaggtcggc aaccacccaa cccggactga ctggcacaat cgcaaaggcc
     8401 agcagcagcg aggtaaaggc aatcatcggt gccagggtaa agatgacgcg atccgagaat
     8461 ttcgggatcc agtcttcttt aaagaacatt ttgatcatgt ccgcaaccag ctggagcgaa
     8521 ccgccccagc caacacggtt aggtccgtaa cggttctgga acagacccag caggcgacgt
     8581 tcgccaaagc tcatgaatgc cccgcaggtg acaaccacca gcaggatcac caccgctttg
     8641 aggatggtca gcaggatctc aatcagttcc ggtgatatcc aactcattgt tgtgcctcct
     8701 tgagatcctc aagatgcgcg ccagccagca ccggagcaat gccggacata cccatcggca
     8761 aacccacctg ccctgccgtc agcccttcag cgatttcaac cggcagcgtg accgtgttgc
     8821 catcgtaact aaaggagacg cgagcgcctg cgttcacgcc caacttcgcg gcatccgctg
     8881 ggttgagttt gatgtacggc tgcggcatac ggctctggaa gaccggagca cgctgtgaca
     8941 attcatcgct gccaaacagg tggtaatacg gcgcgatacg ccatttcccg tcctgcggct
     9001 ggaagcgtgc cggtacgctg gtgaagtaat ccagaccatt ttcgctggtt tcaaacagac
     9061 gcacgcccgg atcgccaaag cgcagtttgc cgcccacttc gtcctggaat ttgttccacg
     9121 cctgcgggga gttccagccc ggcgcccagg caaacggcac ttgcgaacgg tgcgcagtcg
     9181 gctggttgtt accttccatc gagaaggtga acatggtgtc aatatcctgc ggctgacgcg
     9241 gctcatgaac gctgatattg gcgcgcatgg cggtacgacc gctgtaacgg tgcggttcac
     9301 gggccagttt ctgcccacga atacggaatg tcgcatccgg cgcagcatct ttgatacctg
     9361 ccagttccgg gattttcgcc acaacagcgt caatcacatg gtcgagctgc gtccagtcca
     9421 cttcacggct cagcagggtg ctgtgcagcg agtgtaacca gcgccagctt tccagcatga
     9481 cagttttgct gtcgtaataa gcaggatcgt aaacctggaa gaaacgttgg gcgcggcctt
     9541 cgttgttgat caccgtaccg tcgctttcag caaagctggc agcagaaagt accagatggg
     9601 cgttttccat aatcgctgtg cgttgatgat caaccaccat caccagcggc gctttagcca
     9661 gcgcagcatt cacgcgggta gcggaagcgt gacgatgcag atcgttttcc agcaccacca
     9721 ccgcgtcggc gcgtccggtt tccagttcgg tcaacgcttc ttcaagcgaa ccgccaccca
     9781 taatgcccag ccccatgctg ttgacggaac gggcaatcat ggtgatacca acgtcagcgc
     9841 cgcgaccttt cagggctttc gcgacgttag ccgcagcctg aatcacctct atgctaccgg
     9901 cgttcgtccc ggagataatc aacggtttct tcgcacctgc cagtgcctgc acgatgacgt
     9961 cgattttgct ttgcagctca ggttcgatac cgtcaaccgc tggcgcagag ttatccagcg
    10021 catgggcgat ggcaaaacct aaacgcgcct gatcttcaac cggtgcgcgg taagtccacg
    10081 ccgcgatatc atccagacgg gtgtcatcaa cgttggtaac aaacagcgga tgcttcgcac
    10141 gttgaccgat gttgaggatt gccgcaatct gccagtcagc cactttctgt gctgccgcca
    10201 tttcgcgcgc tttacctttc acagcctgac gcactgccag cgcgacgcgc gcgccggtct
    10261 gggtaacgtc ttcgcccagc accagtaccg catcgtaaga ttcgatttcg cgcagagccg
    10321 gagtataaat gccgccttca cgcagcactt tcagcgccag ttgcagacgt tcctgctcac
    10381 cgtgagcgat accggtgtag aagttttctt cgcccaccag ttcacgcagc gcaaagttgc
    10441 tttccacgct ggcacgcgga gaaccaatac cgatcacttt cttcgactga cgcagaatat
    10501 ctgccgcgcc ctgcattgcc tgttcggcgt tgagggtaat gaaatcatcg ccacgacgct
    10561 gtactggctg acgcggacga tccttcaggt tgacgtaacc gtaaccgaaa cgaccacggt
    10621 cgcagaggaa gtagtggttt accgtaccgt tgtaacggtt ttcgatacga cgcagttcgc
    10681 cgtaacgttc accggggctg atgttacagc cgatggaaca ttgctggcag atgctcggcg
    10741 caaactgcat atcccattta cggttgtaac gctcggagtg cgttttgtcg gtaaatacgc
    10801 cggtcgggca aatttcgacc aggttaccgg aaaattcgct ttccagcgtg ccgtcttccg
    10861 ggcgaccgaa gtagacgttg tcgtgcgcac cgtaaacgcc cagatctgta ccgtcagcgt
    10921 aatctttgta gtaacgcaca cagcggtagc aggcgatgca gcggttcatt tcgtgagaga
    10981 tgaatggccc caaatcctga ttacggtggg tacgtttggt gaaacggtag cgacggaagc
    11041 tgtgtccggt catcacggtc atatcctgaa gatggcagtt accgccttct tcacataccg
    11101 gacagtcgtg cgggtggttg gtcattaacc actcgaccac actttcacgg aactgtttcg
    11161 cttcttcgtc gtcaatggaa ataaaggtgc catcggaagc cggtgtcata caggacatca
    11221 ccaggcgacc acgcgtgtct tccgcgtttt ggtattgctt caccgcacac tggcggcaag
    11281 caccgacgct tcccagcgcc ggatgccagc aaaagtaagg aatatcaagg cccagagaca
    11341 gacaagcttc cagcaggttg tccgctccgt tgacctcgta ttctttgccg tctacatgaa
    11401 ttgtagccat tagcatgctt ccagttttct cggtcaggga ccgagcgtta atcgaaattc
    11461 ggttaccagc gctctttcag caggttcggc tgaatcccat taatcaaatg ggtattgctg
    11521 aacggctgtt tgattcccgc ctcaaattct tcgcggaaat atttgatggc gctctgtaac
    11581 ggctccactg caccaggtgc gtgggcacag aaagttttac ccgggcctaa gaatcgacac
    11641 agttgctcaa gtgtttcgat atcgcccggc tgaccttcac cacgctccag cgcacgcaga
    11701 attttcacgc tccacggcag accgtcgcgg cacggcgtac accagccgca ggattcacgg
    11761 gcgaaaaact cttccaggtt acgcaccagc gacaccatgt tgatctcatg gtcaaccgcc
    11821 atcgccagcg ccgtacccag acggcttccc gctttaccga tactttcgaa ttccatcggc
    11881 agatcaaggt gcgcttcggt caggaagtca gtccccgcgc cgcctggctg ccaggcttta
    11941 aatttcagac catcacgcat accaccggcg taatcttcga ggatctcgcg tgcggtggtg
    12001 ccgaacggca gttcccacag tcccggattt ttcacccgac cggagaagcc catcagcttg
    12061 gtgccagcat ctttactttt cgagatgttc tgataccact ccacgccgtt agcgaggatc
    12121 gccggaacgt tacacagggt ttcgacgttg ttgacacagg tcggtttgcc ccatacgccg
    12181 gaggttgccg ggaagggggg tttcgagcgt gggttagcac gacgcccttc cagggagttg
    12241 attaacgctg tttcttcccc gcagatgtag cgccctgccc cggtatggac gaacagttcg
    12301 aagtcgaaac ctgttcccat aatgtttttg ccaagcaagc ccgcttcagt ggcttcggca
    12361 atggcgcggc gcagatttac tgccgcttcg atatattcgc cacgcaggaa gatgtagcca
    12421 cggtaagctt tcagcgcaaa cgcggagatg agcatacctt ccaccagcag gtgcggcagt
    12481 tgctccatca gcaggcggtc tttataggtg cctggctcca tttcatcggc gttacacagc
    12541 aggtaacgga tgttcatgga ttcgtctttc ggcatcaggc tccatttcag gccggtagaa
    12601 aagcccgcgc caccgcgccc tttcagacca gcgtctttta cctgattaac gatttcgtcc
    12661 ggagacagcc cggtcagcgc cttacgcgcg ccttcgtaac cgtttttgct gcgatattcg
    12721 tccagccaca ctggctgttt gtcatcgcgc agacgccagg tcagcggatg cgtttcggga
    12781 gtacggataa tgtttttcat ttataccgct ccagcagttc agggatcgct tccggggtca
    12841 gatgcgcgtg agtatcctca tcgatcatca tgtttggccc tttatcacag ttccccaggc
    12901 agcaagttgg cagcagcgta aagcgaccgt caaatgtcgt ttgccctggt ttgatgttta
    12961 gctttttctc gagcgccgcc tgaataccct ggtaaccgtt gatatgacag accacgctgt
    13021 cgcaataacg gatcacatgg cggccaaccg gctggcggaa gatctggctg tagaacgttg
    13081 ccacaccttc gacgtcgctt gccggaatac ccagcacatc ggcgatcgcg tggatcgcac
    13141 catccggcac ccagccacgc tgcttctgaa cgattttcag cgcttcaatg gacgccgcac
    13201 gcgggtcttc gtagtggtgc atctcgtgct caatcgcttc acgctctgcc gcactcagct
    13261 caaaagcctc ggtttgtggt tgttgattct cgtgcataat tagcggtcca catctgacat
    13321 aacaaaatcg atactgccca gataaacaat caggtcagac accaggctgc cgcggatcgc
    13381 cgccggaatt tgctgcaaat gcgcataact cggcgtgcgg atacgagtgc gataactcat
    13441 ggtgctaccg tcgctggtca ggtagtaact gttgatcccc ttggtcgcct caatcatctg
    13501 gaaagattca ttggcaggca tcaccggccc ccacgacact tgcaggaagt gggtgatcag
    13561 ggtttcgata tgttgcagcg tgcgctcttt cggcggcggc gtggtcagcg ggtgatccgc
    13621 tttgaacggg ccttccggca tgttgttgag gcactgctca agaatgcgca gactctggcg
    13681 cagctcttcc actttcagca ttacgcgggt gtagcagtca gaaacaccac caccaaccgg
    13741 gatttcaaag tcgaagtttt catagccaga ataaggacgc gccttacgca cgtcgaagtc
    13801 gatcccggta gcacgcaggc ccgcgccagt ggtgccccac tccagcgcct ctttcgcgcc
    13861 ataggcggca acgccctggg aacgaccttt cagaatggta ttttgcagcg ccgctttctc
    13921 gtaagacgcc agacgtttcg gcatccagtc gaggaactca cgcagcaggc gatcccagcc
    13981 gcgcggcagg tcgtgcgcta cgccgccaat acggaaccac gccgggtgca tacggaaacc
    14041 cgtgatcgct tccaccagat cgtaaatttt ctgacgatcg gtaaaggcga agaacacggg
    14101 cgtcattgcg ccgacgtcct gaataaaggt cgagatgtac agcaggtggc tgttgatacg
    14161 gaacagttcg gagagcataa cgcgaatgac gttaacgcga tccggcacgg tgatcccggc
    14221 cagtttctct accgccagca cgtaaggcat ttcgttaacg cagccgccga ggtattcaat
    14281 acggtcggta tacggaatgt agctgtgcca ggactggcgc tcgcccattt tctccgcacc
    14341 acggtggtgg tagccgatgt ctggtacgca gtcgacaatc tcttcgccgt cgagttgtaa
    14401 aacgatacgg aaagccccgt gcgccgacgg gtggttcgga ccgaggttga ggaacatgaa
    14461 gtcctcgttt tcggtgccgc gcttcatccc ccactcttcc ggtttgaagg tcagggcttc
    14521 catctccaga tcctgtttgg ctttggtcag ctcaaacggc gagaattcgg tagcgcgcgc
    14581 cgggtaatct ttacgcagcg ggtgaccttt ccaggtttgc ggcatcatga tgcggcgcag
    14641 gttcgggtga ccgtcgaatg taatgccaaa cagatcccag gtttcacgct cataccagtt
    14701 agcgttcggg aacagtttgg tgaaggtcgg tacgtgcagg tcgttttctg ccagcgccac
    14761 cttcagcatg atgtcgcggt tacgatcgat agaaatcaga tggtagaaaa cggaaaaatc
    14821 cgcggcaggt aacccttcgc ggtgcgtgcg cagacgttcg tccatgccgt gtaagtcaaa
    14881 cagcatgacg taaggtttcg gcagtttctt taagaaatcg ccaacttcca gtaattgttc
    14941 acgcttgatc cacacaacgg gaaccccggt gcgagtcgcc tgaacagtaa aggcatccgg
    15001 cccaaaacgg ttgcgcagtt cgccaattac cggatcatca agatgatcgc gggtctgcca
    15061 ggcgggttct tgcgcggtta agtcggtcat attgttcacc attgcaaatg gtccgtggtg
    15121 actgtcggcg cagtaagctt cgcgaaatag atttaggaat aagcgaagaa aaatcccttt
    15181 gccgacaggc gcaaattaaa tctcgtcagg tgtacgcagg ttggttacgg caatgcgttc
    15241 accgcgcttg cgttcgcgct ctgattgcat attggcgcga taaacgccct gatcgccaac
    15301 cacccaggag agcggacgac gttctttacc gatagattcc tgcaacagca tcagtgcctg
    15361 catgtacgct tcaggacgcg gcgggcagcc cgggatatac acatcaaccg ggatgaattt
    15421 atcgacgccc tgcacaacgg aataaatatc gtacatacca ccagagttgg cacaggcacc
    15481 cattgagata acccattttg gttccagcat ctggtcatac agacgctgaa taaccggtgc
    15541 cattttggta aagcaggttc ctgcaaccac catcaggtca gcctgacgcg gcgaagcacg
    15601 caatacttct gcgccaaaac gcgccacgtc atgcaccgcg gtaaacgaag tcaccatttc
    15661 aacgtaacag caggaaagac cgaagttata cggccaaatt gagtttttac gaccccagtt
    15721 aaccatgtca ttgagcttgc ccataaacac gtttttgtta acttcttgct ccagagggtc
    15781 ggttacgatc tcctgctttt gcagggggta acggtcgttc tcaccgttgg gatctatgcg
    15841 ggtgagcgta taatccatct taatgcctcg cggttagcgt tgacgattag cgatactgtt
    15901 cgtttccggg ttcatacgct cgcggcgtga acgcgcgggc gtccagtcca gcgcgccaat
    15961 acgcaccaga taaaccagac ctgccagtaa cacaaaaata aaaattgcag cttccacaaa
    16021 gcctacccag ccgctttcgc ggatagaggt tgaccatgcg aacagataca gcgcttcaac
    16081 gtcgaagata acgaagaaca tggccaccag ataaaacttg gcggacaggc gtaagcgggc
    16141 ggagccgacc gagtcgatac cggattcaaa cggcacgttt ttcgacctcg cgcgtgcgcg
    16201 accgcctaaa aaccaaccgc ctaccagcat caggcaacac aggccaatgg caacgataag
    16261 aaagatagcg aatgcccagt gatgagcgat gacttcagtg gatgttgaca tactcattgc
    16321 ttactcatca aaagtagcgc cagattcact gctcttcacg gcagatggac gccacatcga
    16381 ttcatgggga ggaataaaaa aaaaccttac aatcactgta gaaattcttt tatacagcta
    16441 attgatgtgg tcttttactc ctttctataa ccttttgtca actttaacaa aagtttcttc
    16501 acattagttt acataatatc aacaccatta gcatttaatg ccctttcacc ccagatcctt
    16561 gacgactcca ggataattag atgttgttga atcgtgtccg ttgtgaagca atggaaaaaa
    16621 tacgggtcta ttttgacagg aatttgtgtc gattcctccc cccaaaagag agtattttct
    16681 tgatctgtga cacgcttttg tcattccata acaaaaacgc agcaacaaat ttacgtattt
    16741 tttaacatca ttgtagcagg tgattttttt caggcgatta tttgtgcgta cggggcgtga
    16801 atctctggtg attgaaaaat gaacagtttt gtacgttctg cacgatgtga agaaggttct
    16861 ttactaaaaa aaagccgctg gggtttaaaa cacccccagc ggctcgtttt ttacactatt
    16921 gtctcaggaa ttatctatcg tccgtcgatt actcgatatc cctttcaatc aacaatgaat
    16981 catccccttc cggagcagat attgggctgt attgccacgg attatggtag ctctccatcg
    17041 cctgatagat cacttgggcc agctcattat tactggacgg gtcatagcac agcaaatatt
    17101 cggtatcagg tagcggcggt aagccatcta ctccactcag cacacgcaag tccggactca
    17161 tcatctcgac cggccttgcc gtcacgccaa gaccggcttt cactgccgca cgaacggccg
    17221 gaagcgtcga ggcgacataa gccagtcgcc agggaatatc tgctttatta agcgtcgcca
    17281 gcaccatatc gcgaaacgga cttggatcat ccagcaatac aagagggatc ggctcacctt
    17341 tttgcaatac gtattccgct gcgcagtacc agtgtgttgg cgaggtacgc aggttcaatg
    17401 ccttaaacgc tgaaggacga tgggtggtta ccatcaaatc cacttcctgg gattccagca
    17461 tttctgccat ataggcatta cgtttaacgc ggacatccag cgctaatttc ggataaaccg
    17521 aactcacgcg atttaacagg aaaggtaaga tcgtatcggc agattcatct gaagcaccga
    17581 tagttaacac gccctgaaga ttactgaaca ttaatgatga gcaggcctca tcattaaaac
    17641 gcaggatttt cctggcgtaa ccaagaagtt gaatgccatg ttcagttaac agtttgttgc
    17701 gaccgtgacg agcgaacagt tctttcccaa cgagttgttc cagacgctgc atttgctgac
    17761 ttacggcgga ctgagtacga cacacagcgg cagctgcggc agcaaaagtg ttcagatcgg
    17821 caacagcaac aaatgttctc agcagatcga ggtcgaggtt aattatcgga cgatttgcac
    17881 ttatcatata ttatcactta ctggcggctc atactgagct ggttaatgct gtgcacacac
    17941 aaacaagcaa ttccatttgt aatgtgcctc cctggcagtt tcatccggaa cccggacgaa
    18001 agtaaaaatg catatgagtt gcactaaaaa agcgactcac attgttccgt tataatgcct
    18061 gaagtagatc acagaatata tcttcaggga tcgcatatct attaagttac tcactctttt
    18121 ctatttatga catgcgcgtg tttgtataaa tgtaaatgtg agtccttgtt ccactctcgt
    18181 gcagcatcgc tggtcatacg cgaacacgta caaacagcaa tggtgaggcg gcatcaagag
    18241 cagggatccg tcatttatgc gagcatttta ccccaaaaac cttttattta taagggtcat
    18301 tgcgaattat ctgatgcaaa gttatgttat gttaggcaaa gtaatcttct attattaata
    18361 agcacatcaa aacctttttg aatattaaat aataattaat tagcatcatc ctcattcatt
    18421 aattccgctt aacaatagtt tcacaccttg cccccattgc gacacctcgg aaatcatcac
    18481 gctgttaaac tctccgtaat gcggaaatat catcatcgcg tttcattagt gaattcttaa
    18541 atgaggcatt ttcacacaat tatcttacag ataaaaaaac cagacttaca attaagaatc
    18601 agaacaattc actatataac attgcatgtg aagcatatac acctcattat tttgtcatta
    18661 ttaagttatt aacagcacaa tcgagccttc ccctctggca aaatcttatt ctgcagacct
    18721 tcaaaacacc gtcctggggg agtacattgt tctaagctga cttccacggc agggagtggc
    18781 gataacagca aaaaaggtca agattcatgt cccccattga aaaatccagc aaattagaga
    18841 atgtctgtta tgacatccgt ggtccggtgc tgaaagaagc aaaacgcctg gaagaagaag
    18901 gtaacaaggt actgaaactg aacatcggca acccagcccc gttcggtttt gacgcgccag
    18961 atgaaatcct cgttgacgtg atacgcaacc tgcctaccgc tcaagggtat tgcgattcca
    19021 aaggtcttta ctccgcgcgt aaagccatca tgcagcacta tcaggctcgt ggcatgcgtg
    19081 atgttaccgt ggaagatatt tacatcggca atggtgtatc ggagcttatc gttcaggcaa
    19141 tgcaggcatt gctgaacagc ggggacgaaa tgttggttcc tgcaccagat tacccactat
    19201 ggaccgcggc ggtttcgctt tccagcggta aagcggtgca ttatctttgc gatgaatcct
    19261 ctgactggtt cccggacctc gatgatattc gcgctaaaat tacgcctcgt acgcgtggga
    19321 tcgttattat caacccaaat aacccaaccg gcgcggtata ttccaaagag cttttaatgg
    19381 agattgtgga gattgcacgt cagcataatc tcattatctt cgccgatgaa atttatgaca
    19441 aaattctcta cgacgacgct gagcatcact caattgcgcc gctggcacct gacctgctga
    19501 ccattacctt taatggactg tcgaaaacgt accgcgttgc aggcttccgt caggggtgga
    19561 tggtgttgaa cgggccgaaa aaacacgcca aaggctacat cgaaggtctg gaaatgctgg
    19621 cttcaatgcg cctgtgtgct aacgttcctg cgcaacacgc cattcagacc gcgctgggtg
    19681 gttatcagag catcagtgaa tttattaccc ctggcggtcg tctttatgag cagcgtaacc
    19741 gcgcgtggga attgatcaac gatattccgg gcgtttcctg cgtgaaacct cgtggtgcgc
    19801 tgtacatgtt cccgaaaatc gacgccaaac gctttaacat tcacgacgat cagaaaatgg
    19861 tgctggattt cctgttgcag gaaaaagttc tgttggtgca agggacggca ttcaactggc
    19921 cgtggccgga tcacttccgc attgtcacgc taccgcgtgt cgatgatatc gagctgtctt
    19981 tgagcaagtt cgcgcgtttc ctttctggtt atcatcagct gtaatcttaa tttcactgcc
    20041 ggagattgca tccggcagtg ttatcccgcc acaatgacct gatgatgtca tcatacgtaa
    20101 ggtcactatg aaacagagcc atttttttgc ccatctctcc cgcctgaaac tcattaaccg
    20161 ctggccgctc atgcgcaacg tgcggacgga aaatgtgtcc gaacacagtt tgcaggtagc
    20221 gatggtcgcc catgcgctgg cagctatcaa aaatcggaaa tttggcggta atgtcaacgc
    20281 cgaacgtatc gctttactgg cgatgtacca cgatgcctca gaagtgctca ccggcgatct
    20341 ccctactccg gtgaaatact tcaattcgca aatcgctcag gagtacaagg cgattgaaaa
    20401 aatcgctcag caaaaactgg tcgatatggt tccggaagag ctgcgggata tctttgcgcc
    20461 gttaattgac gagcatgcat atagcgatga agaaaaatcg ctggtgaaac aggcagatgc
    20521 actgtgtgca tatctgaaat gtctggaaga actcgcggcc ggaaataatg aattcttgct
    20581 ggcaaaaacg cgactggaag cgacgcttga agcgcgtcgc agccaggaga tggactactt
    20641 catggaagta tttgttccca gcttccatct ttcgctcgat gagattagcc aggattcacc
    20701 gctgtaagca gccggagtct gcgtcgcatc aggcaataag cgccggatgc gacatcaggc
    20761 tcttgtcaaa acggaaacag catcgggatc atcaccacac aaaccgccat cacgataatg
    20821 gtgaacggta cccccaactt cacaaagtca ctgaagctgt aatttcccgg acctaaaacc
    20881 agtgtgttaa caggtgaaga aaccggtgtc ataaaggcgg cggatgctgc catcgccacg
    20941 accatcgcga atggataagg cgacaccccc atcgttttgg cagcagccag cgcaatcgga
    21001 gccatcaaca ccgccgtcgc ggtattagag ataaatagcc caataaccgc cgacaagaca
    21061 aacaaacaac ccagcatcat atgtggcccg taaccaccgc caatgtccat cagccctttc
    21121 accgccagcg cgacacctcc cgttttctgt aatgccacag caaacggcat catcccaacg
    21181 atcaaaataa tgctcggcca gtgaatggat ttataggcgc tttcagcatc tatacagcgg
    21241 aatttcccca tcagcaggca ggcgatgata gcggcaacag gattaggaat ttcatctgtc
    21301 agcattaacg ccaccattag caccagacag aaaatggcat ggggtgcctg gctgtgcgcg
    21361 ggcgatgctt cactcacctc ttccggtaag ttcagcgcta cgaagtcgcg gccctgtttg
    21421 gccagcatac cgatcagttt ccagttaccc acaaccagga tgatatcgcc cagcagcaga
    21481 ggctcatccg ccagcgaacc ttccagcgcc acgccattgc gctttagccc caccacattc
    21541 agtccgtagc gggtacgaaa accaatttcg cgcaccgatt taccaatcag ttctgactca
    21601 ggaattaatg aaatctctgc catgcccaca tcaagggcct ggtcagaaaa atactcgccg
    21661 cgcagtacca tcggctccag caattgctca ctacaaaatt gccggagatc gacatcagcc
    21721 gcagacatat caataagcaa aacgtcacgc gcgcgaaatt cagaaacccc attaacgttc
    21781 acgataacgc gacgaaaacg ccgccagcgt tcaacaccga tgacgttagc gccataacgc
    21841 tcacgtaatt tgagatcatc cagccgttga ccaatcattg gcgatccggg gcgaatagcc
    21901 agacgtcgcg cacgcccggt cagtcgatat tcacggataa gatcgcgaaa ggttcgacgc
    21961 gtccagcctt cgcgctgcgg ggtctgggta tcccctttca gcatgaaacg catcactaac
    22021 atatacaaaa tacccagcac cagcacgacc aggccaatag gtgttacgct aaagaaactg
    22081 aagccgtgat agccttcacg cagcaattca ctgttgacta ccaggttcgg cggcgtcgcc
    22141 accagcgtca tcatgccgct aatcagcccg gcaaaactta acggcatcat cagacgtgac
    22201 ggcgaagttt gcatacgcat ggcaacgctt aacaccacgg gaataaagat agcgacaacg
    22261 ccggttgaac tcataaacgc gccaagcccc gcgacggtca gcatcaacaa aaccaacatt
    22321 ttgatttcac tgttgcccgc aactttgacc agccatgttc ccattacggt ggcaacaccg
    22381 gtacggacca aaccatcgcc aataataaac aaggcggcaa tcaggacaac gttaggatca
    22441 gaaaagccgg aaaatacttc tgggactgtc agcgttccgc ttaatgcaaa cgcgacaata
    22501 acaaacaaag cgaccgcatc catacgcact ctgcccgtcg caaacaagac gatggcaacg
    22561 gccagtaatg aaagaaccca aatcaattca ccgttcacaa cttatccttg ttaattgagg
    22621 gggatgactt gattctgcca taaaaaagcc ccgacgagac ggggctaaat catgatcagg
    22681 tgtttcactg aataataaca tcgccatttg gctgtttggt cacagtaatt tgctccagac
    22741 tgtggaggac caaatcgacc tcattcaggc gcggggtatc tgccggagcg ttaaccgcaa
    22801 tgacatggca acccgccgcc aggccagaaa gcacgccagc gggagcatct tccaccacca
    22861 cacactcctg cggcgcaagc cccagcagct gcgcgcctaa cagatacgca tcaggttctg
    22921 gttttccgcg cttcactcgc tcagcggtta caaacacctc tggtgcggga agccccgcta
    22981 ttttatggcg cgctcgcgct accggcatgg agccagaagt cacaatggcc cacggaatac
    23041 ctgctttatt caaatgattg agtaaggcga ttgcccccgg aagcgcggta ataccttcgg
    23101 tttccgtggc ctcgatttgc tccagacgcg taaactcggc ggcaatatca gcctcggatt
    23161 tgcccgccat aaaatggcgc agagaggtga tcgcctgttt accgtgaatg aaagccagca
    23221 cctcttccgg cgctaaccca tgacgtctgg cccagttgct ccacgcccgt tctaccgcag
    23281 gcagggaatc caccagcgtt ccatcaagat caaacagaaa acctttgcac cgcacgcggg
    23341 cctcctcagg cgttgataat ttgattaatt tcgttggcgc tcaaatggta ctgacgcggg
    23401 caggcatgcc acacattaag catgcgctga tatttttccc acattggcgt ctgggcgtta
    23461 aaaccgtgag ttccggcgtc aaaatgggta tagcgccctt ccacattaac cataaagcgg
    23521 acataaccga ggtaacgtgc ttcagtggcg gcgtcaaagc cgaggaaggt gacacgacgt
    23581 tcatcgatgg attgctggtc ctgcaaatta gaccaggaaa catgcaacgc atgatacatc
    23641 tccataatgt cgatgatagt gcggcaggtt tcttctttca gctcgccaaa ctcgcgatcc
    23701 agttcacgca tctgtaatcc ataaccacgc tcaatgattg tttgcaggcg acggtaacgt
    23761 tcagcatttg ccggatcgag catagtcatc atcttgtact ggttagacaa aataagacgt
    23821 tgcgcgttgg tcatttccat tgttgactcc tgtatcactc tactacggtg aaaaaaaaga
    23881 aggctgagta tgccttcttt tatatgcgta atcaggggtc aattacaaat catcaaggaa
    23941 agttttatcc agttgtttga aggcacgctt aagcgtgtca gctaatgcct ggtaatcagg
    24001 cttgccttca acgggtgcca acacctgtcc agactcctgc aatttaccgc gaacttcata
    24061 aaaccagttg aggattgcag ggggtaatgg cgtgacagaa cgcttgccca gccaccacaa
    24121 tccctgcatg ggtaaactta aggcgaacag ggcagtggca actgccggcc caagctgacc
    24181 gcccagggca atctgccagc agagagtaaa tacggcgatc ggcggcataa aacggatcgc
    24241 ataacgcgtc atcttgataa cgcgattttc gacaaagacc ggggcaaggc gtttttccag
    24301 cggccacgtc tttgagtaat gctgtccccg gcgaaacaag ctaaaaaaat taacagaacg
    24361 attatccggc gttgacatgc ttcacctcaa cttcacatat aaagattcaa aaatttgtgc
    24421 aaattcacaa ctcagcggga caacgttcaa aacattttgt cttccatacc cactatcagg
    24481 tatcctttag cagcctgaag gcctaagtag tacatattca ttgagtcgtc aaattcatat
    24541 acattatgcc attggctgaa aattacgcaa aatggcatag actcaagata tttcttccat
    24601 catgcaaaaa aaatttgcag tgcatgatgt taatcataaa tgtcggtgtc atcatgcgct
    24661 acgctctatg gctccctgac gtttttttag ccacgtatca attataggta cttccatgtc
    24721 gagtaagtta gtactggttc tgaactgcgg tagttcttca ctgaaatttg ccatcatcga
    24781 tgcagtaaat ggtgaagagt acctttctgg tttagccgaa tgtttccacc tgcccgaagc
    24841 acgtatcaaa tggaaaatgg acggcaataa acaggaagcg gctttaggtg caggcgccgc
    24901 tcacagcgaa gcgctcaact ttatcgttaa tactattctg gcacaaaaac cagaactgtc
    24961 tgcgcagctg actgctatcg gtcaccgtat cgtacacggc ggcgaaaagt ataccagctc
    25021 cgtagtgatc gatgagtctg ttattcaggg tatcaaagat gcagcttctt ttgcaccgct
    25081 gcacaacccg gctcacctga tcggtatcga agaagctctg aaatctttcc cacagctgaa
    25141 agacaaaaac gttgctgtat ttgacaccgc gttccaccag actatgccgg aagagtctta
    25201 cctctacgcc ctgccgtaca acctgtacaa agagcacggc atccgtcgtt acggcgcgca
    25261 cggcaccagc cacttctatg taacccagga agcggcaaaa atgctgaaca aaccggtaga
    25321 agaactgaac atcatcacct gccacctggg caacggtggt tccgtttctg ctatccgcaa
    25381 cggtaaatgc gttgacacct ctatgggcct gaccccgctg gaaggtctgg tcatgggtac
    25441 ccgttctggt gatatcgatc cggcgatcat cttccacctg cacgacaccc tgggcatgag
    25501 cgttgacgca atcaacaaac tgctgaccaa agagtctggc ctgctgggtc tgaccgaagt
    25561 gaccagcgac tgccgctatg ttgaagacaa ctacgcgacg aaagaagacg cgaagcgcgc
    25621 aatggacgtt tactgccacc gcctggcgaa atacatcggt gcctacactg cgctgatgga
    25681 tggtcgtctg gacgctgttg tattcaccgg tggtatcggt gaaaatgccg cgatggttcg
    25741 tgaactgtct ctgggcaaac tgggcgtgct gggctttgaa gttgatcatg aacgcaacct
    25801 ggctgcacgt ttcggcaaat ctggtttcat caacaaagaa ggtacccgtc ctgcggtggt
    25861 tatcccaacc aacgaagaac tggttatcgc gcaagacgcg agccgcctga ctgcctgatt
    25921 tcacaccgcc agctcagctg gcggtgctgt tttgtaaccc gccaaatcgg cggtaacgaa
    25981 agaggataaa ccgtgtcccg tattattatg ctgatcccta ccggaaccag cgtcggtctg
    26041 accagcgtca gccttggcgt gatccgtgca atggaacgca aaggcgttcg tctgagcgtt
    26101 ttcaaaccta tcgctcagcc gcgtaccggt ggcgatgcgc ccgatcagac tacgactatc
    26161 gtacgtgcga actcttccac tacgacggcc gctgaaccgc tgaaaatgag ctacgttgaa
    26221 ggtctgcttt ccagcaatca gaaagatgtg ctgatggaag agatcgtcgc aaactaccac
    26281 gctaacacca aagacgctga agtcgttctg gttgaaggtc tggtcccgac acgtaagcac
    26341 cagtttgccc agtctctgaa ctacgaaatc gctaaaacgc tgaatgcgga aatcgtcttc
    26401 gttatgtctc agggcactga caccccggaa cagctgaaag agcgtatcga actgacccgc
    26461 aacagcttcg gcggtgccaa aaacaccaac atcaccggcg ttatcgttaa caaactgaac
    26521 gcaccggttg atgaacaggg tcgtactcgc ccggatctgt ccgagatttt cgacgactct
    26581 tccaaagcta aagtaaacaa tgttgatccg gcgaagctgc aagaatccag cccgctgccg
    26641 gttctcggcg ctgtgccgtg gagctttgac ctgatcgcga ctcgtgcgat cgatatggct
    26701 cgccacctga atgcgaccat catcaacgaa ggcgacatca atactcgccg cgttaaatcc
    26761 gtcactttct gcgcacgcag cattccgcac atgctggagc acttccgtgc cggttctctg
    26821 ctggtgactt ccgcagaccg tcctgacgtg ctggttgccg cttgcctggc tgccatgaac
    26881 ggcgtagaaa tcggtgccct gctgctgact ggcggctacg aaatggacgc gcgcatttct
    26941 aaactgtgcg aacgtgcttt cgctaccggc ctgccggtat ttatggtgaa caccaacacc
    27001 tggcagactt ctctgagcct gcagagcttc aacctggaag ttccagttga cgatcacgag
    27061 cgtatcgaga aagttcagga atacgttgct aactacatca acgctgactg gatcgattct
    27121 ctgactgcca cttctgagcg cagccgtcgt ctgtctccgc cagcgttccg ttatcagctg
    27181 actgaacttg cgcgcaaagc gggcaaacgt atcgtactgc cggaaggtga cgaaccgcgt
    27241 accgttaaag cagccgctat ctgtgctgaa cgtggtatcg caacttgcgt actgctgggt
    27301 aatccggcag agatcaaccg tgttgcagcg tctcagggtg tagaactggg tgcaggcatt
    27361 gaaatcgttg atccagaagt ggttcgcgaa agctatgttg gtcgtctggt cgagctgcgt
    27421 aagaacaaag gcatgaccga aaccgttgcc cgcgaacagc tggaagacaa cgtggtgctc
    27481 ggtacgctga tgctggaaca ggatgaagtt gatggtctgg tttccggtgc tgttcacact
    27541 accgcaaaca ccatccgtcc gccgctgcag ctgatcaaaa ctgcaccggg cagctccctg
    27601 gtatcttccg tgttcttcat gctgctgccg gaacaggttt acgtttacgg tgactgtgcg
    27661 atcaacccgg atccgaccgc agaacagctg gcagaaatcg cgattcagtc cgctgattcc
    27721 gctgcagcct tcggtatcga accgcgcgtt gctatgctct cctactccac cggtacttct
    27781 ggtgcaggta gcgacgtaga aaaagttcgc gaagcaactc gtctggcgca ggaaaaacgt
    27841 cctgacctga tgatcgacgg tccgctgcag tacgacgctg cggtaatggc tgacgttgcg
    27901 aaatccaaag ctccgaactc tccggttgca ggtcgcgcta ccgtgttcat cttcccggat
    27961 ctgaacaccg gtaacaccac ctacaaagcg gtacagcgtt ctgccgacct gatctccatc
    28021 gggccgatgc tgcagggtat gcgcaagccg gttaacgacc tgtcccgtgg cgcactggtt
    28081 gacgatatcg tctacaccat cgcgctgact gcgattcagt ctgcacagca gcagtaatct
    28141 cgtcatcatc cgcagctttg cgctgcggat atctgaaccg gaaatagtca ctatttccgg
    28201 ttttttattc tcttaatttg cattaatcct ttctgattat cttgcttaac tgcgctgcat
    28261 caatgaattg cgccatctca ctttgcatac ttaccacttt gttttgtgca agggaatatt
    28321 tgcgctatgt ccgcaatcac tgaatccaaa ccaacaagaa gatgggcaat gcccgatacg
    28381 ttggtgatta tcttttttgt tgctatttta accagccttg ccacctgggt agttccggtg
    28441 gggatgtttg acagtcagga agtgcagtat caggttgatg gtcaaacaaa aacacgcaaa
    28501 gtcgtagatc cacactcatt tcgcattctg actaacgaag caggcgaacc tgagtatcac
    28561 cgcgtacagc tgttcacgac gggcgatgaa cgcccgggcc tgatgaactt cccgtttgaa
    28621 gggttaacct caggatcgaa atacgggaca gccgttggca tcatcatgtt tatgctggtg
    28681 attggcggcg cgtttggcat tgtgatgcgt acaggaacca ttgataacgg tatcctggcg
    28741 cttattcgcc atacccgcgg gaatgaaatt ctctttattc ctgcgctgtt tattctgttt
    28801 tcacttggcg gcgcggtatt tggtatgggg gaagaggccg tcgcctttgc cattatcatc
    28861 gcaccgctaa tggtccggct gggctatgac agtattacca ccgtcctggt gacctatatt
    28921 gccacgcaaa tcggttttgc cagttcgtgg atgaacccgt tttgtgtggt tgttgctcag
    28981 gggattgccg gcgttccggt gctttctggc tccgggttgc gcatcgtggt gtgggttatc
    29041 gccactctga ttggcctgat ctttaccatg gtgtacgcct cacgagtgaa aaagaatcct
    29101 cttctgtcac gcgtgcatga gtccgaccgc ttctttcgtg aaaagcaggc ggatgttgaa
    29161 caacgtccgt ttacctttgg tgactggctg gtattgattg tcctgaccgc cgtaatggtc
    29221 tgggtgattt ggggcgtgat cgttaatgcc tggtttattc cagaaattgc cagccagttc
    29281 ttcaccatgg gtctggtgat tggcatcatc ggcgttgttt tccgccttaa cggtatgacg
    29341 gttaatacca tggcttcatc cttcaccgaa ggggcgcgaa tgatgatcgc ccctgccctg
    29401 ctggtgggtt tcgccaaagg gattttgctg ctggtcggta atggtgaagc gggtgatgcc
    29461 agcgtgttaa atactatcct caacagcatt gccaatgcca ttagcggtct ggacaacgcg
    29521 gtcgcggcct ggtttatgtt gctcttccag gcggtattta atttcttcgt gacgtccggt
    29581 tctggtcagg cggcgttaac catgccgtta ctggcaccgc ttggcgatct ggtcggtgtt
    29641 aaccgtcagg ttaccgtgct ggctttccag tttggtgatg gcttcagtca catcatttac
    29701 ccgacctcag cttcgttaat ggcgacgctc ggtgtttgcc gggtggactt ccgtaactgg
    29761 ctgaaggtgg gcgcgaccct gcttggactg ctgtttatta tgtccagcgt cgtggtgatc
    29821 ggcgctcagt tgatgggcta ccactaaaaa tgttaagagc cgcaattgcg gctctttttt
    29881 cattctgccg tttcagtctc tacggcttca tttttggcat tgcgcttcat ccacaacgct
    29941 agcgctttca gcgagtctgg agtgaactca tcgcagcgtg cggtgatttc ttccggcgtc
    30001 agccagcaaa cttcactgac ttcatcttcc tgtagggcga agggaccgtg agagacgcag
    30061 ctgaacaatg cgccccagac acggcaattt ttatcttcga aatagaactg cccgtgctcg
    30121 gcaaagggga caccggcaat gcccaactct tcttccgctt cgcgacgcgc ggattccagc
    30181 agttgctcat cggcctgaac cacaccgcct gcggtcgcat ctaacatgcc gggtaaaaag
    30241 tcttttgtct cggtacgacg ctggaccaga attttgccca tgccatcatg cacgacgatg
    30301 taagttgcac gatgacgcag acactgtgcc cgcatttgtt cccggctggc ttgtgcaatg
    30361 acttcgttct cttcattgac aatatccacc cattcagtac ttgccaaacg acgctgttcc
    30421 attatcagga aaccttcttt ttctggcgct cttacggcgc attttgagtt gtgggtaaat
    30481 tacggattaa tcgcgacctg cgcaatgata ctttgatcat tgagtgcgat tacactaagt
    30541 acgtcattat ccagcatgcc ataactcgcc ggattaccgc ctttcggaat actcaccgag
    30601 ccggggttga agtggaaaat ctccccccgc tgttctgcca ctggcagatg ggtatgaccg
    30661 tacaccagca catcgttctg gtttaaagca ggtagatttt ccgggccaaa aagatgacca
    30721 tgcgtcaaaa acagacgttg tttttccagt aatacctgtt gccacggcgc ggttatcggg
    30781 aaatgcagca gcatttgatc cacttcgctg tcgcagttgc cgcgcacagc gataacctta
    30841 tgtgccactt cattaagccg ttcagcgact ttggctggcg cgtaaccctc cggtaaagca
    30901 ttacgcgggc cgtgattcaa cacgtcgcca aggatcacca gccactgggc accgctttgg
    30961 gcaaacaact ccagaacacg ttccgtcgcc ggtaacgacc catgaatgtc cgatgcaaac
    31021 atcagtttca tcactcactc ctcgtcgaaa aaacgtaagc tatgatactg gattctgtcg
    31081 ttgctatcag ccagattgct tcgccgaaag tgcaataaaa cgctggacag acgctcgctg
    31141 ccactggaat gtcgcataat ccaccaggcg ttctggcacc tcatcgccat gtagtaccag
    31201 gcggttaatc attagcgcca gatcagtatc agcaatgcac cattcaccaa ataaattcgg
    31261 ctgacccagt gctaacaaat gttctgccat cgcgaacagt ttctctgcac tggcttttcc
    31321 ctcggccgtt agtggcgctt ttttcgcccc cgcaaagaca acatccgtcg gacgctcttc
    31381 gcggatgggc atcagatcgc tgcgcagcca ggcctgaatc tgtcgtgcac gcgcacgatt
    31441 ttctaaatca agcggataaa tacgttccca ggtcggtggc gcaaatcgat cttccagata
    31501 ctccgcaatg gcagaagatt cactcaactc aaaatcatcg atttgtaata acggcacacg
    31561 gcgtgtctga ccgtaacctt gccacgtcgg ctgcaaatgt tcaccgctgt cgaggtcgat
    31621 ggtcttgata tgaaacgaca ggcctttttc ctgcaacgcc acccaggcgg ataacacata
    31681 aggggagaaa aagtgggcat ctgaccaaag cgtgatagcg ggtttactca ttatgtcctc
    31741 ggcaataaag ggggctggct atcaaactat agagcctttt tgtcactgtc acgtgacgaa
    31801 tactcacgta agtcgccgcg ctttctatac ttgtggtgtt cagatgatta aacaaccgga
    31861 gctgcaatga tcgatctcta tttcgccccg acacccaatg gtcacaaaat tacgctgttt
    31921 ctcgaagaag cagagcttga ttatcgcttg attaaggtag acctggggaa aggcggtcag
    31981 tttcgtccgg aatttttgcg catttcgccc aacaacaaaa ttccggcaat tgttgatcat
    32041 tctcctgccg atggcggcga accgttaagc ctctttgagt ctggtgccat tttgttgtat
    32101 ctggctgaga aaacaggact ctttttgagt catgaaacgc gtgagcgcgc cgccacatta
    32161 cagtggttat tctggcaggt aggcggactg gggccgatgc ttgggcaaaa tcatcatttt
    32221 aatcacgcag ccccccaaac cattccttac gctattgaac gttatcaggt tgaaactcag
    32281 cgtctttacc atgtactgaa caagcggctg gaaaactcgc cctggctggg aggcgagaac
    32341 tacagcattg cggatattgc ctgctggccg tgggttaatg cctggactcg ccagcgaatt
    32401 gacctcgcaa tgtatccggc agtcaagaac tggcatgagc ggatccgttc gcgccctgcc
    32461 accgggcagg cactgctaaa agcacaactc ggtgatgagc gttcggatag ttaacagaaa
    32521 caggttctcg tgtattattt catcctaagt aaaacaacgg agaacctgca atggcacaac
    32581 ctgccgctat tattcgtata aagaaccttc gtttacgtac gtttatcgga attaaggaag
    32641 aagaaattaa caaccgtcag gatattgtta tcaatgtgac gatccactac cccgccgata
    32701 aagcacgcac tagcgaagat atcaacgatg cgctgaatta tcgcaccgta acgaaaaaca
    32761 ttattcagca tgtagagaat aaccgtttct ctttgctgga aaaattaact caggatgtgc
    32821 tcgatatcgc acgtgaacat cactgggtga cgtatgctga agtggagatc gataaactgc
    32881 acgcgctgcg ctacgccgat tcggtatcca tgaccttaag ctggcagcgt taaccgccat
    32941 atcgggaggc tgcatgaaca tagtgatcac cggagggacg ggattaattg gtcgccattt
    33001 gattccacgt ttgctggagc tgggccatca aatcacggta atgacgcgta acccgcagaa
    33061 agccagttcc gttctcggcc ctcgggtgac actatggcaa gggcttgccg atcaaagcaa
    33121 cctcaacggc gttgatgcgg taatcaacct ggccggagaa ccgattgctg ataaacgctg
    33181 gactcacgag caaaaagagc gtctctgcca aagccgctgg aatatcacgc aaaaactggt
    33241 cgatttgatt aatgccagcg acacgccacc gtcggtactc atttccggct cggcaacggg
    33301 ctattatggc gatttaggtg aagtggtggt taccgaagag gaaccgccgc ataacgaatt
    33361 tacccataaa ctctgcaccc gctgggaaga aattgcctgc cgggcgcaaa gtgacaaaac
    33421 gcgagtgtgc ctgctgcgta ccggcgtagt gctggcaccg gatggcggta ttctcggtaa
    33481 aatgctgccg ccgtttcgtc ttggcctggg cgggccgatt ggttccggtc ggcagtatct
    33541 ggcctggatt catatcgatg atatggtcaa cggcattctc tggctgctgg ataacgagct
    33601 gcgcgggcca tttaatatgg tttcgcctta cccgatacgc aatgaacaat ttgcccatgc
    33661 gctcggtcat gcgctgcatc gcccggctat tttgcgcgtc cccgcaaccg ccattcggct
    33721 gttaatgggc gaatcttcag tactggtatt aggtggacaa cgcgcgctgc ctaaacggct
    33781 ggaagaagcg ggttttgcgt ttcgttggta cgatttagaa gaggcgctgg cggatgtcgt
    33841 tcgctgatgt ggtttactgc aaacatccgc cagttaactc ccggtgttac agggttagtg
    33901 gctttgcgcg ataagatcgt ctggtgaaag tcgggtcagc gtcaggatga cttcgtggtc
    33961 aaatcctttt tccagcatct cctgagcaat acgcagagct tcttcgtgtt tgccctgcat
    34021 tgcgccttct tcacgtaatc tgtcagcaat ggtcatcagt ttctcctttt cttgtggtgc
    34081 gcgttctgtt atctcaccaa taaatgcacg gaaacgctgg gcatctcccg tttgtaatac
    34141 ataattaaac agggctttta gctgtctgtc attagtgttc cctgtaacta gcagcgaaac
    34201 aatttggtcg actaatccca acagatcgcg ctgacgaata tgtttctgaa ttaactccaa
    34261 cagcgccatt ttgcgatgtt gcataatctc gtcatccggc accacggtaa tatccaccaa
    34321 cggaaaagcc gatgaatata ttttacgggc aatcgcaggc tcggcaaatt catcaagcca
    34381 gcagagtgaa taaggataag gacttctgca accatgataa aacagcatcg ggatcaccaa
    34441 tggaagctct ttatagcccg catcaagatg gttttgcatt gccgcaatgg aataacgcat
    34501 catgcgaaaa gccattaatt cttccggctt actttggtgc tctatcacta cataaatata
    34561 acccactccc tcctgcgttt tcacagacca caagaggtcg gaataatatt gccgcaggtc
    34621 ttcatcaata aaactgtttg gttccagttt aagcgtcgtt aaatcacaca gtttgcgcag
    34681 cggcgcggta agatgaatat caataaaatc ccgcgcggtg tctggatggc gtaaaaaaga
    34741 tttaaatacc gcatcatgcg gcgtggaagt tgtcgatatt gtcatggcgt tccgtcaccc
    34801 ctcaaattta agatgacgcg acaataacca cgattaacac ccaatgcagc aggcagtttt
    34861 tatctttgga cagcgaattc agaagtattt ttagcggact gcaactttta catttcagcg
    34921 gaagctgact cgcaaattcc ccttgaaaat actccggcag cgttagccac cggagaggca
    34981 attatttcag cgaaccttta aggaactgtt gcagacgagg gctttgcggg ttgccaaata
    35041 actgctccgg cgcgccttct tcctctattt tcccctgatg gaggaaaatg acgtgagtag
    35101 aaacatgacg agcaaagccc atttcgtgag tcactaccac catggttttc ccctcttctg
    35161 ccagctgctg cataatgcgc aacacttcgc ctaccagttc aggatcgagc gccgaggtag
    35221 gttcatcaaa cagtaaaact tccggttcca tcgccagcgc ccgcgcgata gaaacacgct
    35281 gttgctgacc gccggaaaga tgcaccggat atttcccctg tgcacgttcg tctatcccga
    35341 cttttgccag atacttcacc gcccgctcgc gcgcttcctg cttgctcagg cccaacacct
    35401 gaatcggcgc ttccatgacg ttttccagca ccgtcatatg gctccagaga ttgaagtgct
    35461 ggaataccat cgtcaggcgt gtgcgcagta agcgcagttg atttttatcg gcgactttga
    35521 gttgaccgtc tttgtcgcgc accagattga tcgtctggcc attgaccacg atcgcccctt
    35581 cactcggttt ttcgaggaag ttaatgcagc gcagaaaggt acttttcccc gatcccgacg
    35641 atccaatgat gcttattaca tctccggcat tcgcttgcag tgacacccct ttcagcactt
    35701 cgtgttcgcc atagcgtttg tgcaaatcga taacgtttaa tttattctcg gacatcgtat
    35761 tctcagtgcg ttgaagaagg tttcacatgc tgcaaccagc gtttttccgc tctgcgaaag
    35821 aggctgatca ggacataaga gatgattaaa tagagcaccg cggcaatgcc gaaggcagta
    35881 aaaggttgat acgtggcggc gttaatatcg cgggctattt tcagcagatc cggcaccgtg
    35941 gcagtaaatg ccaacgcagt agagtgcagc atcaggatca cttcgttgct gtatgccggt
    36001 aacgcaatac gcagcgcaga aggcaaaata atgcagcgat acattttaaa agtcgagaag
    36061 ccataggctc tggcggcttc aatttcccca tgcggaaccg aacggattgc cccagcaaaa
    36121 atctcggtag tgtaagcgca ggtgttaagc gtcagcgcca gcacggtaca gttcaggcca
    36181 ctgcggaaaa aggcgttaag aaactcggtc cccttaacaa tctccagcgt atacatgccg
    36241 gaatagaaca ccagcaactg aacatacagc ggcgtaccgc gaaaaatata ggtaaataac
    36301 cagattggaa actggatgta tttattactg gagacacgac caatcgccag aaacagcgcc
    36361 aggactccgc ctatcactac cgacaaaata agcagccaca gggtgatcgc cacaccagta
    36421 aagcgataac cgtcggtcca cagcagcggt ttccagtatt catgtaagat ttcgatcaca
    36481 gatcagccct cttcacaccc acggagtagc ggcgctcaag gaacagcagc acaccattgg
    36541 aaacggtggt gaaaaccaag taaatcacgc cacagacgat ggcgaaatag aacggttccc
    36601 aggtactttt gcctgccagc tgcgtggctt tgaccacatc ttccaggccg agtaacgaaa
    36661 ccagagcggt agatttaagg atcacctgcc agttgttgcc aatgcctggc agagcgtaac
    36721 gcatcatcgc cggaaacatg atccgccgaa acacttgccc acgagtaaaa ccaaacgccg
    36781 tcgccgcctc tatatgtcct ttcggcactg ccataaaagc accacggaac gtttcggtaa
    36841 aataagcacc gtagataaaa ccgagagtga taataccagc gaccatcgga tcgatatcaa
    36901 tctgcccgac gcccatcgcc tccgtcaccg tgtttagcgc aatctgcaaa ccgtagaaaa
    36961 tcagcagcat caacactaag tccggcacgc cacgaatcag cgtggtgtac ccttcgaaaa
    37021 tcagccccga aagccgattt tgcgagagct taccgccagc gccaattaaa ccgatgatta
    37081 cagcgagcac tacagagctg atagccagct ccagcgtgac gagcgcaccc tgtaaaataa
    37141 cacctgaaaa cccatacaac atgctgcctg tcctgtcgtg tgtggtgaat taccgcctct
    37201 tgtctccctc cggttacccg aagggagcgg gctttctttc accgatggcg attaaccacc
    37261 ataaacatca aaatcgaagt actttttcgc taatttctcg taagtaccgt cagcgcgcat
    37321 ttcggcaaag gctttgttca gtgcctcgcg cagttcgtta tcttctttac gcaggcccat
    37381 gccggtccct acgccaaaca gtttttcatc tttaacagac gggccaccga atttgtaatc
    37441 tttaccgaca ggttgtttga ggaaaccttc gctggcagcg acctcatcct ggaacgcggc
    37501 atcaatacgt ccggcagtca ggtcagaata aatgttgtcc tgcccctgat acgagacgat
    37561 ttcaatgcct tttggtgccc aatgttcatt accgaacgtc tcctgggtgg tgccctgcaa
    37621 tacgcctacc cgtttgcctt tcagcgactc gactgtcggc tgaatgtcag aatttttcgc
    37681 caccaccaaa cgagaatcgg cagcgtacag tttgtcggtg aaggctattt cttgctgacg
    37741 tttttccgta atggaaagcg atgacatgat ggcgtcaatc ttcttcgctt ttaaggacgg
    37801 gattaacgca tccagcggat tttcgacaaa cgtacattgc gtattgatgc gtttgcataa
    37861 ttcctttgcc agatcgatat cgaagccaac cagttcgcct tgtgaatttt ttgattcaaa
    37921 tggcgcatag gtcgggtcgg taccgatgcg gatgttttgc ggaatcgcag caaatgccgc
    37981 agttgcgctg gagaaggcca gaaccagaga gagcgatagc accagttttt tcataatgtc
    38041 ctcaactgac agtcttttta tagggaatat ttacaggttt gttacactta tcgtgccata
    38101 aaattgacca tcaaggcaaa atatcccgcc ccgttaggcg tattattttt cattaaaaat
    38161 gcttaagtat gcatttcaat gcaccacgat agtgcaacaa acctggcgtg caccatgatg
    38221 atcattccat caggcacagc ttccctgcga cgtatcagtc accgtagaca ttaaagtcaa
    38281 aatacttttt cgccatcttg tcgtaagtgc cgtcctgacg cagctctcca agcgccttat
    38341 taaacgcagc cgtcagttca gtatcatctt tacgtagccc tacaccggtg ccatcaccga
    38401 agtatttttt gtctttcact gatgagccag caaaggcgaa gtctttacca gcaggttgct
    38461 tgaggaatcc ttcgctggca gcaacttcat cctgcagtgc agcatccaga cgtcctgcag
    38521 ccagatcgga atagaccaaa tcctggttgg cataggccac cacatccaca cctttgctac
    38581 gccaggtctc gttagcgtaa gcttcctggg ttgatccctg cagcacacca acatgtttac
    38641 ctttcagtga atccagcgtt ggctgaatcg gcgaaccttt ggcggcaatc aaacgagaat
    38701 ctgcggcgta caacttgtcg gagaaagcaa tctcctgctg acgtttatcg gtaatggaga
    38761 gcgacgaaat aatggcgtcg atttttttcg ctttcagtga ggggatcagc gcgtcaaagt
    38821 cactggcaac ccaggtacat ttcacctgca tccgtttgca catctcgtta ccgagatcga
    38881 tatcaaagcc aacaaaatca cctttagcat ctttcgacga gaacggcgca taggtggtat
    38941 cggttccgat acgtaccgtc tccggtagcg ccgcatagct ggaagccgct gcggagagac
    39001 cgactaacaa agacagagcg agaatcgact tcttcataca taaccctcaa gtgaaaatgg
    39061 cttttttatg ttgtgtattg tgttgtgtgt ttgcaggctc tttcatgcag gtcttatgcc
    39121 atcttgacga caacagtaac attcaacgtt aaatgtgtta ataagacgtt gcattattgt
    39181 cctgaagttg aagatagcag gtatagcggt tgaatcgcag cgtttcgatt gaatggcaga
    39241 aacaaaatgt cgaggatttg atcgcggttg caaaattgcc ctgaaacagg gcaacagcgg
    39301 ggttatgcgc cctgccagcg ggcaaagaga tcttcaggaa gggttattgc aaactggtca
    39361 agaacacgat taaccgtctg atttatcaca tcatcaaggg attgcgggcg atgataaaac
    39421 gccggaacgg gaggcataat caccgcaccg atttctgccg cctgagtcat taaacgcaga
    39481 tgacctaagt gcaatggtgt ttcacgcacg cagagcacca acgggcgacg ctctttcagc
    39541 accacatctg ccgcacgggt cagtaagcca tcagtatagc tatggacaat gccggaaagg
    39601 gttttgattg aacagggtaa aatcaccatc cccagcgtct ggaaagaacc ggaagagatg
    39661 ctggcggcaa tatcgcgcgc atcgtgcgtg acatcggcta acgcctgcac ttcgcgcagg
    39721 gaaaaatccg tttcgaggga taaggtctgg cgcgccgcct ggctcattac cagatgcgtt
    39781 tcgatatctg tgacatcgcg cagaacctgt aataagcgca caccataaat cgcgccgctg
    39841 gcaccgctga tgcccacaat aagtcgtttc ataaatagtt gccctgtcag acttgcaggc
    39901 agactttgca ggatttcggc gggagttgca agtcagggtg ccagaccggc accctgagcg
    39961 aaggcatcat ccttcgttat gcatttcgag attttccact tcgttctgac gttgcactgc
    40021 tttggcgtcg tcattacgta aagtatcgag gaaatcgagg tagccctgat caacatcttt
    40081 ggtgacgtag acgccgttga acaccgagca ttcaaactgc tggatatccg ggttttcagc
    40141 gcgaacggcg tcgatcagat cgttcagatc ctggaaaatc aacccgtcag caccgatgat
    40201 ctggcgaatt tcatctactt cgcgaccgtg agcgatcagt tccgtagcgc tcggcatatc
    40261 gataccgtaa acgttcggga agcgaatttc cggtgccgca gaagcgaggt acactttctt
    40321 cgctccggct tcgcgtgcca tctcgataat ctgctcagaa gtggtgccac ggacgataga
    40381 gtcgtcgacc agcaggacgt ttttatcgcg gaactcggcg cggttggcgt tcagtttacg
    40441 gcgcacggac ttacgacgca gctgctggcc cggcatgatg aaggtgcggc caacatagcg
    40501 gtttttaacg aagccctggc ggtacggttt gcccagaata cgcgcaattt ccagcgcgat
    40561 atcacacgag gtttccggga tcgggatcac cacgtcgata tccagatctt cccattcgcg
    40621 ggcaattttc tcgcccagct tcgtgcccat attcacacgc gcgctgtaaa cggaaatttt
    40681 gtcgataaac gagtccgggc gagcaaagta tacatactca aacaggcacg gattgctgac
    40741 cggattgtca gcacattgac gggtaaacaa ctgcccttct tcagtaatgt aaatcgcttc
    40801 gccaggcgcg acgtcacgca ggaaatcaaa gcccagtgta tcgagcgcaa cgctttcgga
    40861 agcgaccata tattctgtgc ggttctcgtc aatatcacgt tttcccagta cgagcggacg
    40921 aataccgttc ggatcgcgga aagcaaccat accgtggccg ataatcatcg ccacacaggc
    40981 atacgcgccg cggattaagc ggtttgtagc agcgatggcg gcgaaaatgt tgtcggcttc
    41041 cagcgggtag tggcggaagt tgtccagctc gctggcgaag atattaagca gaatttccga
    41101 gtcggaagtg gtgttgatgt ggcggcgttt ttcttcaaac agttttttac gcaactcgtg
    41161 agcgttggtc agattgccgt tgtgggcaag cgtaatgcca tacggagagt taacgtaaaa
    41221 cggctgcgct tcagaggcgc tggagctgcc agccgtaggg taacgcacat gaccaatgcc
    41281 catattgccc tgcaaacgct gcatatggcg agcttcaaat acatcgctca ccagcccgtt
    41341 cgctttacgc aaacggaagc agttattggc atctatggtg atgatgccgg cggcatcctg
    41401 accgcgatgc tgaagcaccg ttaaggcatc ataaatcgac tggttaaccg gcataacacc
    41461 ggcgataccg acaataccgc acatacgtct ttttcctcgt taagccacat ctcagagcac
    41521 ttacgctctg ggcaagaaac ttgacgagct ttgcagataa tcaaaaaacc atctgatgat
    41581 aaaactgaac tgcggaatca gttgtgattt actccagtct tcgcttttcg acaccccggt
    41641 aaaggagtcg agaaagaaga gaatagcagc aacaatcaac acaccgcgca atgcaccgaa
    41701 acagacgccc agcacccgat cggtgcctga caaccccgtt ttctccacca gctggcctat
    41761 cacgaagttc acgatagcgc caacgatcag ggtggcgata aacaggaccg cgatggcaat
    41821 cccatttcga accagttcgt cttcaaagcc cgtaaaccag actgacaggt aagtgtagta
    41881 atgactggca acaaagaaag cacaacccca tgtcaccagc gataacgctt cacgaacaaa
    41941 gccgcggatc aggctaacca gagaggaaaa agcaatcacc gcgattatgg cgtaatcaat
    42001 ccagaccata tgtgtcccac gattttacgc cctgtcatcc tgttcggggc gcattctaac
    42061 agaaaaagaa aacgtttgcg tagggatttc cttcccgcgc atcaataaaa atggcgctga
    42121 aaaaatattc aacgccatcg actttttatg cctttgcggc atcggacaat gcgtgtcgga
    42181 tgcggcgtaa acgccttatc cgacctacgg ttctacccc
//
LOCUS       DAPGUL010000028        42201 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.028, whole genome shotgun sequence.
ACCESSION   DAPGUL010000028 DAPGUL010000000
VERSION     DAPGUL010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 42201)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42201)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42201
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.028"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..217)
                     /locus_tag="RHX21_001676"
     CDS             complement(<1..217)
                     /locus_tag="RHX21_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1986876.1"
                     /translation="MSGKPAARQGDMTQYGGSIVQGSAGVRIGAPTGVACSVCPGGVT
                     SGHPVNPLLGAKVLPGETDLALPGPLPF"
     gene            complement(377..589)
                     /gene="rpmE"
                     /locus_tag="RHX21_001677"
     CDS             complement(377..589)
                     /gene="rpmE"
                     /locus_tag="RHX21_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HDV1986877.1"
                     /translation="MKKDIHPKYEEITASCSCGNVMKIRSTVGHDLNLDVCSKCHPFF
                     TGKQRDVATGGRVDRFNKRFNIPGSK"
     gene            792..2990
                     /gene="priA"
                     /locus_tag="RHX21_001678"
     CDS             792..2990
                     /gene="priA"
                     /locus_tag="RHX21_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HDV1986878.1"
                     /translation="MPVAHVALPVPLPRTFDYLLPEGMTVKAGCRVRVPFGKQQERIG
                     VVVSVSDVSELPLNELKAVVEVLDVEPVFTHSVWRLLLWAADYYHHPIGDVLFHALPI
                     LLRQGRPAANAPMWYWFATEQGQAVDLNSLKRSPKQQQALAALRQGKIWRDQVATLEF
                     NDAALQALRKKGLCDLASETPEFSDWRTNYAVSGERLRLNTEQATAVGAIHSAADTFS
                     AWLLAGVTGSGKTEVYLSVLENVLAQGKQALVMVPEIGLTPQTIARFRERFNAPVEVL
                     HSGLNDSERLSAWLKAKNGEAAIVIGTRSALFTPFKNLGVIVIDEEHDSSYKQQEGWR
                     YHARDLAVYRAHSEQIPIILGSATPALETLCNVQQKKYRLLRLTRRAGNARPAIQHVL
                     DLKGQKVQAGLAPALITRMRQHLQADNQVILFLNRRGFAPALLCHDCGWIAECPRCDH
                     YYTLHQAQQHLRCHHCDSQRPVPRQCPSCGSTHLVPVGLGTEQLEQTLAPLFPGVPIS
                     RIDRDTTSRKGALEQQLAEVHRGGARILIGTQMLAKGHHFPDVTLVALLDVDGALFSA
                     DFRSAERFAQLYTQVAGRAGRAGKQGEVVLQTHHPEHPLLQTLLYKGYDAFAEQALAE
                     RRMMQLPPWTSHVIVRAEDHNNQHAPLFLQQLRNLILSSPLADDKLWVLGPVPALAPK
                     RGGRWRWQILLQHPSRVRLQHIISGTLALINTIPDSRKVKWVLDVDPIEG"
     gene            3146..4171
                     /gene="cytR"
                     /locus_tag="RHX21_001679"
     CDS             3146..4171
                     /gene="cytR"
                     /locus_tag="RHX21_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CytR"
                     /protein_id="HDV1986879.1"
                     /translation="MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRV
                     EKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDPFFSEIIRGIEVTAANHGYLVLI
                     GDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
                     LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVD
                     PQYIARGDFTFEAGSKAMQQLLDLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLS
                     IIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMHGQHVGSGSRLMDCELIIR
                     GSTRALP"
     gene            4263..5222
                     /gene="ftsN"
                     /locus_tag="RHX21_001680"
     CDS             4263..5222
                     /gene="ftsN"
                     /locus_tag="RHX21_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsN"
                     /protein_id="HDV1986880.1"
                     /translation="MAQRDYVRRSQPAPSRRKKSTSRKKQRNLPAVSPAMVAIAAAVL
                     VTFIGGLYFITHHKKEESETLQSQKVTGNGLPPKPEERWRYIKELESRQPGVRAPTEP
                     SAGGEVKTPEQLTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQ
                     QLAEQQRLAQQSRTTEQSWQQQTRTSQAAPVQAQPRQSKPASSQQPYQDLLQTPAHTT
                     AQSKPQQAAPVARAADAPKPTAEKKDERRWMVQCGSFRGAEQAETVRAQLAFEGFDSK
                     ITTNNGWNRVVIGPVKGKENADSTLNRLKMAGHTNCIRLAAGG"
     gene            5315..5845
                     /gene="hslV"
                     /locus_tag="RHX21_001681"
     CDS             5315..5845
                     /gene="hslV"
                     /locus_tag="RHX21_001681"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease subunit HslV"
                     /protein_id="HDV1986881.1"
                     /translation="MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVI
                     AGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADET
                     ASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELSAREIAEKALDIAGDIC
                     IYTNHFHTIEELSYKA"
     gene            5855..7186
                     /gene="hslU"
                     /locus_tag="RHX21_001682"
     CDS             5855..7186
                     /gene="hslU"
                     /locus_tag="RHX21_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019841241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase ATPase subunit"
                     /protein_id="HDV1986882.1"
                     /translation="MSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEEL
                     RHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRD
                     LTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQTEQQQEPSAARQAFR
                     KKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKI
                     KDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGESSGPDVSREG
                     VQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQA
                     LTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGA
                     RRLHTVLERLMEEISYDASDLSGQNITIDADYVSKHLDALVADEDLSRFIL"
     gene            7253..8179
                     /gene="menA"
                     /locus_tag="RHX21_001683"
     CDS             7253..8179
                     /gene="menA"
                     /locus_tag="RHX21_001683"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HDV1986883.1"
                     /translation="MTEQQISRTQAWLESLRPKTLPLAFAAIIVGTALAWWQGHFDPL
                     VALLALITAGLLQILSNLANDYGDAVKGSDKPDRIGPLRGMQKGVITQQEMKRALIIT
                     VVLICLSGLALVAVACHTLADFVGFLILGGLSIIAAITYTVGNRPYGYIGLGDISVLV
                     FFGWLSVMGSWYLQAHTLIPALILPATACGLLATAVLNINNLRDINSDRENGKNTLVV
                     RLGEVNARRYHACLLMGSLVCLALFNLFSLHSLWGWLFLLAAPLLVKQARYVMREMDP
                     VAMRPMLERTVKGALLTNLLFVLGIFLSQWAA"
     gene            8272..8757
                     /gene="rraA"
                     /locus_tag="RHX21_001684"
     CDS             8272..8757
                     /gene="rraA"
                     /locus_tag="RHX21_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E activity regulator RraA"
                     /protein_id="HDV1986884.1"
                     /translation="MKYDTSELCDIYQEDVNVVEPLFSNFGGRASFGGQIITVKCFED
                     NGLLYDLLEQNGRGRVLVVDGGGSVRRALVDAELARLAVQNEWEGLVIYGAVRQVDDL
                     EELDIGIQAMAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDI
                     E"
     gene            complement(8842..9087)
                     /gene="zapB"
                     /locus_tag="RHX21_001685"
     CDS             complement(8842..9087)
                     /gene="zapB"
                     /locus_tag="RHX21_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septal ring assembly protein ZapB"
                     /protein_id="HDV1986885.1"
                     /translation="MTMSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLSQEVQ
                     NAQHQREELERENNHLKEQQNGWQERLQALLGRMEEV"
     gene            9512..10357
                     /gene="glpF"
                     /locus_tag="RHX21_001686"
     CDS             9512..10357
                     /gene="glpF"
                     /locus_tag="RHX21_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol uptake facilitator protein GlpF"
                     /protein_id="HDV1986886.1"
                     /translation="MSQTSTLKGQCIAEFLGTGLLIFFGVGCVAALKVAGASFGQWEI
                     SVIWGLGVAMAIYLTAGVSGAHLNPAVTIALWLFACFDKRKVIPFIVSQVAGAFCAAA
                     LVYGLYYNLFFDFEQTHHIVRGSVESVDLAGTFSTYPNPHINFVQAFAVEMVITAILM
                     GLILALTDDGNGVPRGPLAPLLIGLLIAVIGASMGPLTGFAMNPARDFGPKVFAWLAG
                     WGNVAFTGGRDIPYFLVPLFGPIVGAIVGAFAYRKLIGRHLPCDICVVEEKETTTPSE
                     QKASL"
     gene            10380..11888
                     /gene="glpK"
                     /locus_tag="RHX21_001687"
     CDS             10380..11888
                     /gene="glpK"
                     /locus_tag="RHX21_001687"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDV1986887.1"
                     /translation="MTEKKYIVALDQGTTSSRAVVMDHDANIISVSQREFEQIYPKPG
                     WVEHDPMEIWATQSSTLVEVLAKADISSDQIAAIGITNQRETTIVWEKETGKPIYNAI
                     VWQCRRTAEICEHLKRDGLEDYIRSNTGLVIDPYFSGTKVKWILDHVEGSRERARRGE
                     LLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHTLDWDDKMLEVLDIPREMLPEV
                     RRSSEVYGQTNIGGKGGTRIPISGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNT
                     GEKAVKSENGLLTTIACGPTGEVNYALEGAVFMAGASIQWLRDEMKLINDAYDSEYFA
                     TKVQNTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNANHIIRATLESIAYQTRDV
                     LEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGL
                     AVGFWQNLDELQEKAVIEREFRPGIETTERNYRYAGWKKAVKRAMAWEEHDE"
     gene            12023..13033
                     /gene="glpX"
                     /locus_tag="RHX21_001688"
     CDS             12023..13033
                     /gene="glpX"
                     /locus_tag="RHX21_001688"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphatase"
                     /protein_id="HDV1986888.1"
                     /translation="MRRELAIEFSRVTESAALAGYKWLGRGDKNTADGAAVNAMRIML
                     NQVNIDGTIVIGEGEIDEAPMLYIGEKVGTGRGDAVDIAVDPIEGTRMTAMGQANALA
                     VLAVGDKGCFLNAPDMYMEKLIVGPGAKGTIDLNLPLADNLRNVAAALGKPLSELTVT
                     ILAKPRHDAVIAEMQQLGVRVFAIPDGDVAASILTCMPDSEVDVLYGIGGAPEGVVSA
                     AVIRALDGDMNGRLLARHDVKGDNEENRRIGEQELARCKAMGIEAGKVLRLGDMARSD
                     NVIFSATGITKGDLLEGISRKGNIATTETLLIRGKSRTIRRIQSIHYLDRKDPEMQVH
                     IL"
     gene            13130..13876
                     /gene="fpr"
                     /locus_tag="RHX21_001689"
     CDS             13130..13876
                     /gene="fpr"
                     /locus_tag="RHX21_001689"
                     /EC_number="1.18.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin--NADP(+) reductase"
                     /protein_id="HDV1986889.1"
                     /translation="MADWVTGKVTKVQNWTDALFSLTVHAPVLPFTAGQFTKLGLEID
                     GERVQRAYSYVNSPDNPDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDE
                     VPHCETLWMLATGTAIGPYLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEK
                     RYEGKLRIQTVVSRETAAGSLTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQMV
                     RDTQQLLKETRQMTKHLRRRPGHMTAEHYW"
     gene            complement(13881..14309)
                     /gene="uspD"
                     /locus_tag="RHX21_001690"
     CDS             complement(13881..14309)
                     /gene="uspD"
                     /locus_tag="RHX21_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspD"
                     /protein_id="HDV1986890.1"
                     /translation="MAYKHIGVAISGNEEDALLVNKALELARHNDAHLTLIHIDDGLS
                     ELYPGIYFPATEDILQLLKNKSDNKLYKLTKNIQWPKTKLRIERGEMPETLLEIMQKE
                     QCDLLVCGHHHSFINRLMPAYRGMINKMSADLLIVPFIDK"
     gene            complement(14336..14635)
                     /locus_tag="RHX21_001691"
     CDS             complement(14336..14635)
                     /locus_tag="RHX21_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF406 domain-containing protein"
                     /protein_id="HDV1986891.1"
                     /translation="MKDVVDKCSTKGCAIDIGTVIDNDNCTSKFSRFFATREEAESFM
                     TKLKELAAATSSADEGASVAYKIKELEGQVELDAAFTFSCQAEMIIFELSLRSLA"
     gene            complement(14847..15287)
                     /locus_tag="RHX21_001692"
     CDS             complement(14847..15287)
                     /locus_tag="RHX21_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HDV1986892.1"
                     /translation="MTIQQWLFSFKGRIGRRDFWIWIGLWFAGMLVLFSLAGKNLLDI
                     QTAAFCLVCLLWPTAAVTVKRLHDRGRSGAWAFLMIVAWMLLAGNWAILPGVWQWAVG
                     RFVPTLILVMMLIDLGAFVGTQGENKYGKDTQDVKYKADNKSSN"
     gene            15388..15987
                     /locus_tag="RHX21_001693"
     CDS             15388..15987
                     /locus_tag="RHX21_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiQ family protein"
                     /protein_id="HDV1986893.1"
                     /translation="MKPGCTLFFLLCSALTVTTAAHAQTPDTATTAPYLLAGAPTFDL
                     SISQFREDFNSQNPSLPLNEFRAIDSSPDKANLTRAASKINENLYASTALERGTLKIK
                     SIQMTWLPIQGPEQKAAKAKAQEYMAAVIRTLTPLMTKTQSQKKLQSLLTAGKNKRYY
                     TETEGALRYVVADNGEKGLTFAVEPIKLALSESLEGLNK"
     gene            16095..16862
                     /gene="tpiA"
                     /locus_tag="RHX21_001694"
     CDS             16095..16862
                     /gene="tpiA"
                     /locus_tag="RHX21_001694"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HDV1986894.1"
                     /translation="MRHPLVMGNWKLNGSRHMVHELVSNLRKELAGVAGCAVAIAPPE
                     MYIDMAKREAEGSHIMLGAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYH
                     KESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFE
                     GAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKVDANIAEQVIIQYGGSVNASNA
                     AELFAQPDIDGALVGGASLKADAFAVIVKAAEAAKQA"
     gene            complement(16917..17672)
                     /gene="cdh"
                     /locus_tag="RHX21_001695"
     CDS             complement(16917..17672)
                     /gene="cdh"
                     /locus_tag="RHX21_001695"
                     /EC_number="3.6.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol diphosphatase"
                     /protein_id="HDV1986895.1"
                     /translation="MKKAGLLFLVMIVIAVVAAGIGYWKLTGEESDTLRKIVLEECLP
                     NQQQNQNPSPCAEVKPNAGYVVLKDLNGPLQYLLMPTYRINGTESPLLTDPSTPNFFW
                     LAWQARDFMSKKYGQPVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVREQLDNNLAN
                     ISSRWLPLPGGLRGHEYLARRVTESELVQRSPFMMLAEEVPEAREHMGRYGLAMVRQS
                     DNSFVLLATQRNLLTLNRASAEEIQDHQCEILR"
     gene            complement(17779..18768)
                     /gene="sbp"
                     /locus_tag="RHX21_001696"
     CDS             complement(17779..18768)
                     /gene="sbp"
                     /locus_tag="RHX21_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter
                     substrate-binding protein Sbp"
                     /protein_id="HDV1986896.1"
                     /translation="MNKWGVGLTFLLAATSVMAKDIQLLNVSYDPTRELYEQYNKAFS
                     AHWKQQTGDNVVIRQSHGGSGKQATSVINGIEADVVTLALAYDVDAIAERGRIDKEWI
                     KRLPDNSAPYTSTIVFLVRKGNPKQIHDWNDLIKPGVSVITPNPKSSGGARWNYLAAW
                     GYALHHNNNDQAKAQDFVRALYKNVEVLDSGARGSTNTFVERGIGDVLIAWENEALLA
                     ANELGKDKFEIVTPSESILAEPTVSVVDKVVEKKGTKEVAEAYLKYLYSPEGQEIAAK
                     NYYRPRDAEVAKKYENAFPKLKLFTIDEEFGGWTKAQKEHFANGGTFDQISKR"
     gene            complement(19088..20050)
                     /gene="pfkA"
                     /locus_tag="RHX21_001697"
     CDS             complement(19088..20050)
                     /gene="pfkA"
                     /locus_tag="RHX21_001697"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014072359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDV1986897.1"
                     /translation="MIKKIGVLTSGGDAPGMNAAIRGVVRSALTEGLEVMGIYDGYLG
                     LYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIG
                     GDGSYMGAMRLTEMGFPCIGLPGTIDNDIKGTDYTIGFFTALSTVVEAIDRLRDTSSS
                     HQRISVVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVNEIKAGIAKGKKHAI
                     VAITEHMCDVDELAHFIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLL
                     LAGYGGRCVGIQNEQLVHHDIIDAIENMKRPFKGDWLDCAKKLY"
     gene            complement(20231..21133)
                     /gene="fieF"
                     /locus_tag="RHX21_001698"
     CDS             complement(20231..21133)
                     /gene="fieF"
                     /locus_tag="RHX21_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312867.1"
                     /note="FieF, a metal efflux transporter, is a member of
                     the CDF (cation diffusion facilitator) family of
                     transporters; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family cation-efflux transporter FieF"
                     /protein_id="HDV1986898.1"
                     /translation="MNQSYGRLVSRAAIAATAMASLLLLIKIFAWWYTGSVSILAALV
                     DSLVDIGASLTNLLVVRYSLQPADDNHSFGHGKAESLAALAQSMFISGSALFLFLTGI
                     QHLISPTPMTDPGVGVIVTIVALICTIILVSFQRWVVRRTQSQAVRADMLHYQSDVMM
                     NGAILLALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDEERQEI
                     IDIVTSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDSLPLVQAHMVADQVEQAILRRFP
                     GSDVIIHQDPCSVVPREGKRSMLS"
     gene            complement(21282..21782)
                     /gene="cpxP"
                     /locus_tag="RHX21_001699"
     CDS             complement(21282..21782)
                     /gene="cpxP"
                     /locus_tag="RHX21_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell-envelope stress modulator CpxP"
                     /protein_id="HDV1986899.1"
                     /translation="MRIVTAAVMASTLAVSSLSHAAEVGSGDNWHPGEELTQRSTQSH
                     MFDGISLTEHQRQQMRDLMQQARHEQPPVNVSELETMHRLVTAENFDENAVRAQAEKM
                     ANEQIARQVEMAKVRNQMYRLLTPEQQAVLNEKHQQRMEQLRDVTQWQKSSSLKLLSS
                     SNSRSQ"
     gene            21932..22630
                     /gene="cpxR"
                     /locus_tag="RHX21_001700"
     CDS             21932..22630
                     /gene="cpxR"
                     /locus_tag="RHX21_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response regulator transcription
                     factor CpxR"
                     /protein_id="HDV1986900.1"
                     /translation="MNKILLVDDDRELTSLLKELLEMEGFNVIVAHDGEQALDLLDDS
                     IDLLLLDVMMPKKNGIDTLKALRQTHQTPVIMLTARGSELDRVLGLELGADDYLPKPF
                     NDRELVARIRAILRRSHWSEQQQNNDNGSPTLEVDALVLNPGRQEASFDGQTLELTGT
                     EFTLLYLLAQHLGQVVSREHLSQEVLGKRLTPFDRAIDMHISNLRRKLPDRKDGHPWF
                     KTLRGRGYLMVSAS"
     gene            22627..24000
                     /gene="cpxA"
                     /locus_tag="RHX21_001701"
     CDS             22627..24000
                     /gene="cpxA"
                     /locus_tag="RHX21_001701"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress sensor histidine kinase CpxA"
                     /protein_id="HDV1986901.1"
                     /translation="MIGSLTARIFAIFWLTLALVLMLVLMLPKLDSRQMTELLDSEQR
                     QGLMIEQHVEAELANDPPNDLMWWRRLFRAIDKWAPPGQRLLLVTTEGRVIGAERSEM
                     QIIRNFIGQADNADHPQKKKYGRVELVGPFSVRDGEDNYQLYLIRPASSSQSDFINLL
                     FDRPLLLLIVTMLVSTPLLLWLAWSLAKPARKLKNAADEVAQGNLRQHPELEAGPQEF
                     LAAGASFNQMVTALERMMTSQQRLLSDISHELRTPLTRLQLGTALLRRRSGESKELER
                     IETEAQRLDSMINDLLVMSRNQQKNALVSETLKANQLWGEVLDNAAFEAEQMGKSFSV
                     NFPPGPWPLYGNPNALESALENIVRNALRYSHTKIEVGFAVDKDGITITVDDDGPGVS
                     PEDREQIFRPFYRTDEARDRESGGTGLGLAIVETAIQQHRGWVKAEDSPLGGLRLVIW
                     LPLYKRS"
     gene            complement(24106..24780)
                     /gene="yiiM"
                     /locus_tag="RHX21_001702"
     CDS             complement(24106..24780)
                     /gene="yiiM"
                     /locus_tag="RHX21_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418346.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-N-hydroxylaminopurine resistance protein"
                     /protein_id="HDV1986902.1"
                     /translation="MRYPVDVYTGKIQAYPEGKPSAIAKIQVDGELMLTELGLEGDEQ
                     AEKKVHGGPDRALCHYPREHYLYWAREFPEQAELFVAPAFGENLSTDGLTESNVYMGD
                     IFRWGEALIQVSQPRSPCYKLNYHFDISDIAQLMQNTGKVGWLYSVIAPGKVSADAPL
                     ELVSRVSDVTVQEAAAIAWHMPFDDDQYHRLLSAAGLSKSWTRTMQKRRLSGKIEDFS
                     RRLWGK"
     gene            complement(24929..25912)
                     /gene="kdgT"
                     /locus_tag="RHX21_001703"
     CDS             complement(24929..25912)
                     /gene="kdgT"
                     /locus_tag="RHX21_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709713.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate transporter"
                     /protein_id="HDV1986903.1"
                     /translation="MQIKRSIEKIPGGMMLVPLFLGALCHTFSPGAGKYFGAFTNGMI
                     TGTVPILAVWFFCMGASIKLSATGTVLRKSGTLVVTKIAVAWVVAAIASRIIPEHGVE
                     VGFFAGLSTLALVAAMDMTNGGLYASIMQQYGTKEEAGAFVLMSLESGPLMTMIILGT
                     AGIASFEPHVFVGAVLPFLVGFALGNLDPELREFFSKAVQTLIPFFAFALGNTIDLTV
                     IAQTGLLGILLGVAVIIVTGIPLIIADKLIGGGDGTAGIAASSSAGAAVATPVLIAEM
                     VPAFKPMAPAATSLVATAVIVTSILVPILTSIWSRKVKARAAKIEILGTVK"
     gene            complement(26172..26792)
                     /gene="sodA"
                     /locus_tag="RHX21_001704"
     CDS             complement(26172..26792)
                     /gene="sodA"
                     /locus_tag="RHX21_001704"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Mn]"
                     /protein_id="HDV1986904.1"
                     /translation="MSYTLPSLPYAYDALEPHFDKQTMEIHHTKHHQTYVNNANAALE
                     SLPEFANLPVEELITKLDQLPADKKTVLRNNAGGHANHSLFWKGLKKGTTLQGDLKAA
                     IERDFGSVDNFKAEFEKAAASRFGSGWAWLVLKGDKLAVVSTANQDSPLMGEAISGAS
                     GFPILGLDVWEHAYYLKFQNRRPDYIKEFWNVVNWDEAAARFAAKK"
     gene            27077..28111
                     /gene="rhaT"
                     /locus_tag="RHX21_001705"
     CDS             27077..28111
                     /gene="rhaT"
                     /locus_tag="RHX21_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose/proton symporter RhaT"
                     /protein_id="HDV1986905.1"
                     /translation="MSNAITMGIFWHLIGAASAACFYAPFKKVKKWSWETMWSVGGIV
                     SWIILPWAISALLLPNFWAYYSSFSLSTLLPVFLFGAMWGIGNINYGLTMRYLGMSMG
                     IGIAIGITLIVGTLMTPIINGNFDVLISTEGGRMTLLGVLVALIGVGIVTRAGQLKER
                     KMGIKAEEFNLKKGLVLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYV
                     VIMGGGAIINLGFCFIRLAKVKDLSLKADFSLAKSLIIHNVLLSTLGGLMWYLQFFFY
                     AWGHARIPAQYDYISWMLHMSFYVLCGGIVGLVLKEWNNAGRRPVTVLSLGCVVIIVA
                     ANIVGIGMAN"
     gene            complement(28108..28974)
                     /gene="rhaR"
                     /locus_tag="RHX21_001706"
     CDS             complement(28108..28974)
                     /gene="rhaR"
                     /locus_tag="RHX21_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418342.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator RhaR"
                     /protein_id="HDV1986906.1"
                     /translation="MAEVATVAHQLKLLKDDFFASDQQAVAVADRYPQDVFAEHTHDF
                     CELVIVWRGNGLHVLNDRPYRITRGDLFYIHADDKHSYASVNDLVLQNIIYCPERLKL
                     NLDWQGAIPGFNASAGQPHWRLGSMGMAQARQVIGQLEHESSQHVPFANEMAELLFGQ
                     LVMLLNRHRYTSDSLPPTSSETLLDKLITRLAASLKSPFALDKFCDEASCSERVLRQQ
                     FRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSNYFSVVFTRETGMT
                     PSQWRHLNSQKD"
     gene            complement(29030..29866)
                     /gene="rhaS"
                     /locus_tag="RHX21_001707"
     CDS             complement(29030..29866)
                     /gene="rhaS"
                     /locus_tag="RHX21_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator RhaS"
                     /protein_id="HDV1986907.1"
                     /translation="MTVLHSVDFFPSGNASVAIEPRLPQADFPEHHHDFHEIVIVEHG
                     TGIHVFNGQPYTITGGTVCFVRDHDRHLYEHTDNLCLTNVLYRSPDRFQFLAGLNQLL
                     PQELDGQYPSHWRVNHSVLQQVRQLVAQMEQQEGENDLPSTASREILFMQLLLLLRKS
                     SLQENLENSASRLNLLLAWLEDHFADEVNWDAVADQFSLSLRTLHRQLKQQTGLTPQR
                     YLNRLRLMKARHLLRHSEASVTDIAYRCGFSDSNHFSTLFRREFNWSPRDIRQGRDGF
                     LQ"
     gene            30154..31623
                     /gene="rhaB"
                     /locus_tag="RHX21_001708"
     CDS             30154..31623
                     /gene="rhaB"
                     /locus_tag="RHX21_001708"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HDV1986908.1"
                     /translation="MTFRNCVAVDLGASSGRVMLARYERECRSLTLREIHRFNNGLHS
                     QNGYVTWDVDSLESAIRLGLNKVCEEGIRIDSIGIDTWGVDFVLLDQQGQRVGLPVAY
                     RDSRTNGLMAQAQQQLGKRDIYQRSGIQFLPFNTLYQLRALTEQQPELIPHIAHALLM
                     PDYFSYRLTGKMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAWFGRPTHPGNVIG
                     HWICPQGNEIPVVAVASHDTASAVIASPLNGSRAAYLSSGTWSLMGFESQTPFTNDTA
                     LAANITNEGGAEGRYRVLKNIMGLWLLQRVLQEQQINDLPALISATQALPACRFIINP
                     NDDRFINPETMCSEIQAACRETAQPIPESDAELARCIFDSLALLYADVLHELAQLRGE
                     DFSQLHIVGGGCQNTLLNQLCADACGIRVIAGPVEASTLGNIGIQLMTLDELNNVDDF
                     RQVVSTTANLTTFTPNPDSEIAHYVAQIHSTRQTKELCA"
     gene            31620..32879
                     /gene="rhaA"
                     /locus_tag="RHX21_001709"
     CDS             31620..32879
                     /gene="rhaA"
                     /locus_tag="RHX21_001709"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HDV1986909.1"
                     /translation="MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDD
                     VSGFENPEGSLTGGIQATGNYPGKARNASELRADLEQAMRLIPGPKRLNLHAIYLESD
                     TPVSRDQIKPEHFKNWVEWAKANQLGLDFNPSCFSHPLSADGFTLSHADDSIRQFWID
                     HCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLNP
                     AHHIDAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAA
                     MLYVPQLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHDLFDRVHIGLDFFDASINR
                     IAAWVIGTRNMKKALLRALLEPTAELRKLEAAGDYTARLALLEEQKSLPWQAVWEMYC
                     QRHDTPAGSEWLESVRAYEKEILSRRG"
     gene            33330..34154
                     /gene="rhaD"
                     /locus_tag="RHX21_001710"
     CDS             33330..34154
                     /gene="rhaD"
                     /locus_tag="RHX21_001710"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HDV1986910.1"
                     /translation="MQNITQSWFVQGMIKATTDAWLKGWDERNGGNLTLRLDEADIAP
                     YHDNFHQQPRYIPLSQPMPLLANTPFIVTGSGKFFRNVQLDPAANLGIVKVDSDGAGY
                     HILWGLTNEAVPTSELPAHFLSHCERIKATNGKDRVIMHCHATNLIALTYVLENDTAV
                     FTRQLWEGSTECLVVFPDGVGILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSG
                     PTLDETFGLIDTAEKSAQVLVKVYSMGGMKQTISREELIALGKRFGVTPLASALAL"
     gene            34164..34478
                     /gene="rhaM"
                     /locus_tag="RHX21_001711"
     CDS             34164..34478
                     /gene="rhaM"
                     /locus_tag="RHX21_001711"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HDV1986911.1"
                     /translation="MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGAHNYAIY
                     LDKARNLLFAMVEIESEERWNAVASTDVCQRWWKYMTDVMPANPDNSPVSSELQEVFY
                     LP"
     gene            complement(34519..35913)
                     /locus_tag="RHX21_001712"
     CDS             complement(34519..35913)
                     /locus_tag="RHX21_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate porin"
                     /protein_id="HDV1986912.1"
                     /translation="MKKSILSLAIGLLLTCSTGMAKTQHLTLEQRMALLEERLEAAEM
                     RAAKAESQVKQLQTQQAAEIREIKAAQGNTPVNGQATAESAKKNATSPNLLLSGYGDL
                     KIYGDVEFNMDAESNHGLLAMTNADVNSDPTNEQWNLNGRILLGFDGMRKMDNGYFAG
                     FSAQPLGDMHGSVNIDDAVFFFGKENDWKVKVGRFEAYDMFPLNQDTFVEHSGNTAND
                     LYDDGSGYIYMMKEGRGRSNAGGNFLVSKQLDNWYFELNTLLEDGTSLYNDGNYHGRD
                     MEQQKNVAYLRPVIAWSPTEEFTVSAAMEANVVNNAYGYTDSKGNFVDQSDRTGYGMS
                     MTWNGLKTDPDNGIVVNLNTAYLDANNEKDFTAGINALWKRFELGYIYAHNKIDEFSG
                     VVCDNDCWIDDEGTYSIHTIHASYQFANVMDMENFNIYLGTYYSILDSDGDKKHGDDT
                     DDRYGARVRFKYFF"
     gene            36390..36836
                     /locus_tag="RHX21_001713"
     CDS             36390..36836
                     /locus_tag="RHX21_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HDV1986913.1"
                     /translation="MAALTASCIALNIQGNGAYSVLKQLATIALQNGFITDSHQFLQT
                     LLLREKMHSTGFGSGVAVPHGKSACVKQPFVLFARKAQAIDWKASDGEDVNCWICLGV
                     PQSGEEDQVKIIGTLCRKIIHQDFIHQLQQGDTDQVLALLNQTLSS"
     gene            36847..38298
                     /locus_tag="RHX21_001714"
     CDS             36847..38298
                     /locus_tag="RHX21_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418335.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIBC"
                     /protein_id="HDV1986914.1"
                     /translation="MESSLRIVAITNCPAGIAHTYMVAEALEQKARSLGHTIKVETQG
                     SSGVENRLSSEEIAAADYVILATGRGLSGDDRARFAGKKVYEIAISQALKNIDQIFSE
                     LPTNSQLFAADSGVKLGKQEVQSGSVMSHLMAGVSAALPFVIGGGILVALANMLVQFG
                     LPYTDMSKGAPSFTWVVESIGYLGFTFMIPIMGAYIASSIADKPAFAPAFLVCYLAND
                     KALLGTQSGAGFLGAVVLGLAIGYFVFWFRKVRLGKALQPLLGSMLIPFVTLLVFGVL
                     TYYVIGPVMSDLMGGLLHFLNTIPPSMKFAAAFLVGAMLAFDMGGPINKTAWFFCFSL
                     LEKHIYDWYAIVGVVALMPPVAAGLATFIAPKLFTRQEKEAASSAIVVGATVATEPAI
                     PYALAAPLPMITANTLAGGITGVLVIAFGIKRLAPGLGIFDPLIGLMSPVDSFYLVLA
                     IGLALNISFIIVLKGLWLRRKAKAAQQELVHEH"
     gene            38288..39358
                     /locus_tag="RHX21_001715"
     CDS             38288..39358
                     /locus_tag="RHX21_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDV1986915.1"
                     /translation="MNIELLQQLCEASAVSGDEQEVRDILINTLEPCVNEITFDGLGS
                     FVARKGNKGPKVAVVGHMDEVGFMVTHIDESGFLRFTTIGGWWNQSMLNHRVTIRTHK
                     GVKIPGVIGSVAPHALTEKQKQQPLSFDEMFIDIGANSREEVEKRGVEIGNFISPEAN
                     FACWGEDKVVGKALDNRIGCAMMAELLQTVNNPEITLYGVGSVEEEVGLRGAQTSAEH
                     IKPDVVIVLDTAVAGDVPGIDNIKYPLKLGQGPGLMLFDKRYFPNQKLVAALKSCAAH
                     NDLPLQFSTMKTGATDGGRYNVMGGGRPVVALCLPTRYLHANSGMISKADYEALLTLI
                     RGFLTTLTAEKVNAFSQFRQVD"
     gene            39358..41106
                     /locus_tag="RHX21_001716"
     CDS             39358..41106
                     /locus_tag="RHX21_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative frv operon regulatory protein"
                     /protein_id="HDV1986916.1"
                     /translation="MLNERQLKIVDLLEQQPRTPGELAQQTGVSGRTILRDIDYLNFT
                     LNGKARIFASGSAGYQLEIFERRSFFQLLQKHDNDDRLLALLLLNTFTPRAQLASALN
                     LPETWVAERLPRLKQRYERTCCLASRPGLGHFIDETEEKRVILLANLLRKDPFLIPLA
                     GITRDNLQHLSTACDNQHRWPLMQGDYLSSLILAIYALRNQLTDEWPQYPGDEIKQIV
                     EQSGMFLGDNAVRTLTGLIEKQHQQAQIISADNVQRLLQRVPGIASLNIIDTRLVENI
                     TGHLLRCLAAPVWIAEHRQSSMNNLKAAWPAAFDMSLHFITLLREQLDIPLFDSDLLG
                     LYFACALERHQNERQPIILLSDQNAIATINQLAIERDVLNCRVIIARSLSELVAIREE
                     IEPLLIINNSHYLLDDAVNNYITVKNIITAAGIEQIKHFLATAFIRQQPERFFSAPGS
                     FHYSNVRGESWQHITRQICAQLVAQHHITADEAQRIIAREGEGENLIVNRLAIPHCWS
                     EQERRFRGFFITLAQPVEVNNEVINHVLIACAAADARHELKIFSYLASILCQHPAEII
                     AGLTGYEAFMELLHKG"
     gene            complement(41156..>42201)
                     /locus_tag="RHX21_001717"
     CDS             complement(41156..>42201)
                     /locus_tag="RHX21_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YiiG family protein"
                     /protein_id="HDV1986917.1"
                     /translation="LLSSAIIVAIMSLGLTGCDDKKAETETLPPANSQPAAPAPEAKP
                     TEAPVAKAEAKPETPAQPVVDEQAVFDEKMDVYIKCYNKLQIPVQRSLARYADWLKDF
                     KQGPTGEERTVYGIYGISESNLAECEKGVKSAVALTPALQPIDGVAVSYIDAAVALGN
                     TINEMDKYYTQENYKDDAFAKGKTLHQTFLKNLEAFEPVAESYHAAIQEINDKRQLAE
                     LKNIEEREGKTFHYYSLAVMISAKQINNLISQDKFDAEAAMKKVSELETLVAQAKEAD
                     KGGMNFSFINSAGQYQLEAKKYVRRIRDKVPYSDWDKEQLQDANSSWMVEDSFPRALR
                     EYNEMVDDYNSLR"
BASE COUNT        10290 a        10941 c        10843 g        10127 t
ORIGIN      
        1 tgaacggcag cgggccgggc agggcaaggt cggtttcacc gggaaggacc tttgcaccga
       61 gcaggggatt gaccggatgg ccggacgtca ctccgccggg gcacaccgaa caggccacgc
      121 cggtgggggc accaatgcgc accccggctg aaccctgaac aatgctaccg ccatactgcg
      181 tcatgtcgcc ctgacgcgct gccggttttc cgctcatcgt aaaatccttt tgaaataaat
      241 aagaaccaga agcctagcgc cagtcaacaa caggaaatga taatgagtta acaccccgga
      301 atttttcaga atttataaaa ggcaaattac aggcacaaaa aaagcgccgt gcggcgcttt
      361 tttcggaaat ccggtcttat ttgctgcccg ggatgttgaa acgcttgttg aagcggtcaa
      421 cacggccacc ggtagcaaca tcacgctgtt tgccagtgaa gaatgggtgg cacttgctgc
      481 acacgtcgag gttcaggtca tgaccaacgg tggagcggat tttcattacg ttaccgcaag
      541 agcagctagc agtaatttct tcgtatttcg ggtgaatatc ttttttcatg ggaaaacctc
      601 ggtttaaggc cgcgtcgctc ttccagccct aacgccagac accacgcgat gttaaaagta
      661 tagcttcaat acgatcattt cgtacgaagg cgcgaaatca tacagaaatt aaccagcgta
      721 tgcaaactga tccgcactct tctacggcaa tgtgtatact aacccaccga atttcaagtc
      781 aggatgatgc tatgcccgtt gcccacgttg ccttgcccgt tccgcttcct cgtacctttg
      841 actatctgct gccagaaggc atgacggtta aagccgggtg tcgcgtgcgc gtgccgtttg
      901 gcaaacagca ggagcgcatc ggggttgtgg tgtcagttag cgatgtcagt gagctgccgc
      961 ttaacgagct gaaagcggta gtggaagtgc tggacgttga gccggtattt actcactccg
     1021 tctggcggtt actgctctgg gcggcagatt actatcatca tccgattggc gatgtgctgt
     1081 ttcatgcctt gccgatttta ctgcgccagg ggcggcctgc ggcgaacgcg ccgatgtggt
     1141 actggtttgc cactgaacaa ggccaggcgg tggatctgaa cagcctgaaa cgctccccca
     1201 agcaacaaca ggcgctggcg gcgttacggc aaggcaaaat ctggcgcgac caggtcgcca
     1261 cgctcgaatt taatgatgcc gcgttgcagg cgctacgcaa aaaaggtctg tgtgatttag
     1321 caagtgaaac accagagttt agcgactggc gaacgaacta tgccgtttct ggtgagcggt
     1381 tgcgattgaa taccgaacag gccaccgccg ttggcgcaat tcatagcgcg gcagatactt
     1441 tttctgcctg gctgctggcg ggcgttaccg gttccggtaa aacggaggtt tatctcagtg
     1501 tactggaaaa cgtgctcgct cagggcaaac aggcgctggt gatggtgccg gaaatcggcc
     1561 tgacaccgca aactatcgcc cgttttcgtg aacgttttaa tgcccccgtg gaagttctgc
     1621 attccggcct gaacgacagc gagcgtcttt cggcgtggtt gaaagcgaaa aatggcgagg
     1681 cggcgattgt catcggcacc cgctccgcgc tgtttacgcc gtttaaaaat ctcggggtga
     1741 ttgtcattga tgaagagcac gacagctcct acaagcagca ggaaggctgg cgctatcatg
     1801 cccgcgacct ggcggtttat cgtgcgcaca gcgagcaaat cccgattatt cttggctctg
     1861 caacacccgc actggaaacg ttatgcaacg tccagcagaa aaaataccgc ctgctgcgcc
     1921 tgacgcgtcg ggcggggaat gcgcgtccgg caattcaaca cgtgctggat ttaaaaggtc
     1981 agaaggtgca ggcggggctg gctccggcgt taatcacccg tatgcgccag catttacagg
     2041 ccgacaacca ggttatcctc tttcttaacc gccgtggctt tgcgcctgcc ttgctgtgcc
     2101 acgactgcgg ctggattgcc gaatgtccac gttgcgatca ctactacacg ctgcatcagg
     2161 cgcagcaaca tctgcgctgc caccactgtg acagtcagcg tccggtgccg cgccagtgcc
     2221 cttcctgcgg ttccacgcac ctggtacccg tagggctggg caccgaacag cttgagcaaa
     2281 cgctcgcgcc gctgttccct ggtgtgccca tttctcgtat cgaccgcgat accaccagcc
     2341 gcaaaggggc gctggaacag caactggcgg aagtgcatcg cggcggcgcg aggatcttga
     2401 ttggcacgca aatgctggcg aaaggtcacc actttccgga tgtgacgctg gtggcgttac
     2461 tggatgtgga cggcgcgctg ttttctgccg attttcgctc ggcagaacgt ttcgcccagc
     2521 tttacaccca ggtcgccggt cgtgccgggc gtgcgggtaa acagggcgaa gtggtgctgc
     2581 aaacgcacca tccggaacat cctctgttgc aaacgttgct ctataaaggc tacgacgcct
     2641 ttgccgaaca ggcgctggct gagcgacgca tgatgcagct gccgccgtgg accagccatg
     2701 tgattgtgcg tgcggaagat cataacaatc agcacgcgcc gctgttcctg caacaactgc
     2761 gtaatctgat cctctccagc ccgctggcag acgacaaact gtgggttctc ggcccggttc
     2821 cggctctggc acctaagcgt ggtggccgct ggcgctggca gatcttgttg cagcaccctt
     2881 cccgcgtgcg cttgcaacac atcattagtg gtacgctggc gcttattaat acaataccgg
     2941 attcccgcaa ggtgaaatgg gtgttggatg tcgatcccat cgaaggctaa tgcgcaaacg
     3001 ttgcgaggcg gatcgaaaaa ttcaatattc atcacacttt tcatgaaaat tctgtaaccg
     3061 ttttcacgcg ctatctgcta aaaatgttgc cgatgtgaag taaacatgga tgtagtacgc
     3121 ctgacgtgcc aggcgaggag tgagtgtgaa agcgaagaag caggaaactg ccgcgaccat
     3181 gaaagacgtt gccctcaagg caaaagtctc tacagcgacc gtctcccgag cattaatgaa
     3241 tcccgataaa gtctcccagg ccacccgtaa tcgggttgaa aaagcggccc gggaagtggg
     3301 ttatttaccg cagcctatgg ggcgcaacgt caagcgtaat gaatcccgca ccattctggt
     3361 gattgtcccg gatatctgcg atcccttctt tagcgaaatt attcgcggta tcgaagttac
     3421 ggcggcaaat cacggatatc tggtgctgat tggcgactgt gcgcatcaaa atcagcagga
     3481 aaaaaccttt atcgatttga tcatcaccaa gcaaattgat ggcatgttgt tgctgggttc
     3541 aaggctgccg tttgatgcca gcattgagga acagcgtaat ctgccgccga tggtgatggc
     3601 gaacgaattt gcaccggagc tggagctgcc tacagttcat atcgacaatc tgaccgccgc
     3661 atttgatgca gtaaattatt tatatgagca agggcataaa cggattggct gtatagccgg
     3721 tcccgaagag atgccgctgt gtcactaccg cctgcaaggc tatgttcagg cgctgcgtcg
     3781 ctgcggcatt atggttgatc cgcaatacat cgcccgtggc gacttcacct tcgaagccgg
     3841 aagcaaagcg atgcagcagc tgcttgatct tccacaaccg cctactgctg tcttctgcca
     3901 tagcgatgtg atggcgctcg gcgcactttc tcaggcaaaa cgccaggggc tgaaagtccc
     3961 ggaagacctt tccataatcg gttttgataa catcgacctg acgcaatttt gtgatccgcc
     4021 gctgacaacc atcgcgcagc cgcgttacga aatcggtcgg gaagctatgc tgttattgct
     4081 tgatcaaatg catgggcaac acgttggcag tggctctcgt ttaatggact gcgaacttat
     4141 catccgggga tcaacacgcg cgttacctta aagtaaacct ttaagactgc cgtgactggt
     4201 caaaggcccg ccgcttaagt aacatggcgg gctgacgaac gaataaatac agcgaaacga
     4261 tagtggcaca acgagattat gtacgccgca gccaaccggc accttcgcgg cgaaaaaaga
     4321 gcacctcacg gaaaaagcaa cgaaatctgc ctgcggtttc tcccgctatg gtcgctattg
     4381 ctgccgccgt tcttgtgacc tttatcggtg gtctgtactt cattacgcat cacaagaaag
     4441 aagagtccga gacgctgcaa agccagaaag tgaccggaaa cggactacca ccaaaaccag
     4501 aagaacgctg gcgctacatt aaagagctgg aaagtcgcca gccgggagtg cgtgcgccca
     4561 cagaaccttc tgccggtggt gaagtgaaaa cgccggagca actgacacca gaacaacgtc
     4621 agcttcttga acaaatgcag gctgatatgc gccagcagcc aacgcagctg gttgaagttc
     4681 cgtggaatga acagacgccg gaacagcgtc agcaaacgct acagcgccaa cgtcaggcgc
     4741 agcaattagc ggaacagcaa cgcctggctc agcagtcgcg tacgactgaa caaagctggc
     4801 agcagcagac gcgtacgtcg caagccgcac cggtacaggc gcaaccgcgc cagtctaaac
     4861 cggcttcttc tcagcagccg taccaggatc tgctgcaaac tcctgcgcac acgactgcgc
     4921 agtcgaagcc gcagcaagct gcgccagttg ctcgtgccgc tgacgcgcca aaaccgacgg
     4981 cggagaaaaa agacgaacgc cgctggatgg tgcagtgcgg ttcgttcaga ggcgcggaac
     5041 aggcagagac ggtacgtgct cagctggcgt tcgaaggctt tgactcgaaa atcaccacca
     5101 acaatggctg gaatcgtgtg gtcattggcc cggtgaaagg caaagagaac gcagacagca
     5161 ccctcaatcg gttgaagatg gcgggtcata caaactgcat tcggctcgcc gccgggggtt
     5221 gaaaccctca aaatcccccc catctataat tgcattatgc cccgtacttt tgtacggggt
     5281 ttgtactctg tattcgtaac caaggggtca gctcgtgaca actatagtaa gcgtacgccg
     5341 taacggccat gtggtcatcg ctggtgatgg tcaggccacg ttgggcaata ccgtaatgaa
     5401 aggcaacgtg aaaaaggtcc gccgtctgta caacgacaaa gtcatcgcgg gctttgcggg
     5461 cggtactgcg gatgctttta cgctgttcga actgtttgaa cgtaaactgg aaatgcatca
     5521 gggccatctg gtcaaagccg ccgttgagct ggcaaaagac tggcgtaccg atcgcatgct
     5581 gcgcaaactt gaagcactgc tggcagtcgc ggatgaaact gcatcgctta tcatcaccgg
     5641 taacggtgac gtggtgcagc cagaaaacga tcttattgct atcggctccg gcggccctta
     5701 cgcccaggct gcggcgcgcg cgctgttaga aaacactgaa cttagcgccc gtgaaattgc
     5761 tgaaaaggcg ttggatattg caggcgacat ttgcatctat accaaccatt tccacaccat
     5821 cgaagaatta agctacaaag cgtaaggatc tcccatgtct gaaatgaccc cacgcgaaat
     5881 cgtcagcgaa ctggataagc acatcatcgg ccaggacaac gccaagcgtt ctgtggcgat
     5941 tgctctgcgt aaccgctggc gtcgcatgca gctcaacgaa gagctgcgcc atgaagtgac
     6001 cccgaaaaat atcctgatga tcggcccgac cggtgtcggt aaaactgaaa tcgcccgtcg
     6061 tctggctaag ctggcgaatg cgccgttcat caaagttgaa gcgaccaaat tcaccgaagt
     6121 gggctacgtc ggtaaggaag tggattctat tattcgcgat ctgaccgatg ccgccgtgaa
     6181 aatggtacgc gtccaggcta tcgagaaaaa ccgttatcgc gctgaagaac tggcagaaga
     6241 acgtattctc gacgtgctga tcccaccggc taaaaacaac tggggacaga ccgaacagca
     6301 gcaggaaccg tccgctgctc gtcaggcatt ccgcaaaaaa ctgcgtgaag gccagcttga
     6361 tgacaaagaa atcgagatcg atcttgccgc agcaccgatg ggcgttgaaa ttatggctcc
     6421 tccgggcatg gaagagatga ccagccagct gcagtccatg ttccagaacc tgggcggcca
     6481 gaagcaaaaa gcgcgtaagc tgaaaatcaa agacgccatg aagctgctga ttgaagaaga
     6541 agcggcgaaa ctggtgaacc cggaagagct gaagcaagac gctatcgacg ctgttgagca
     6601 gcacgggatc gtgtttatcg acgaaatcga caaaatctgt aagcgcggcg agtcttccgg
     6661 tccggatgtt tctcgtgaag gtgttcagcg tgacctgctg ccgctggtag aaggttgcac
     6721 cgtttccacc aaacacggga tggtcaaaac tgaccacatt ctgtttatcg cttctggcgc
     6781 gttccagatt gcgaaaccgt ctgacctgat cccggaactg caaggtcgtc tgccaatccg
     6841 cgttgaactg caggcgctga ccaccagcga cttcgagcgt attctgaccg agccgaatgc
     6901 ctctatcacc gtgcagtaca aagcactgat ggcgactgaa ggcgtaaata tcgagtttac
     6961 cgactccggt attaaacgca tcgcggaagc ggcatggcag gtgaacgaat ctaccgaaaa
     7021 catcggtgct cgtcgtttac acactgttct ggagcgttta atggaagaga tttcctacga
     7081 cgccagcgat ttaagcggtc aaaatatcac tattgacgca gattatgtga gcaaacatct
     7141 ggatgcgttg gtggcagatg aagatctgag ccgttttatc ctataatcgc gttcaatcat
     7201 tttcatcatt gtttgatggg gctgaaaggc cccattttta ttggcgcgta ttatgactga
     7261 acaacaaatt agccgaactc aggcgtggct ggaaagttta cgacctaaaa ccctccccct
     7321 cgcctttgct gcaattatcg tcgggacagc gctggcatgg tggcaaggtc acttcgatcc
     7381 gctggtcgcc ctgctggcac taattaccgc cgggctatta cagatccttt ctaacctcgc
     7441 caatgattac ggcgatgcgg taaaaggcag cgataaacct gaccgcattg ggccgctacg
     7501 cggcatgcaa aaaggggtca ttacccagca agagatgaaa cgggcgctca ttattaccgt
     7561 cgtgctcatc tgtctctccg ggctggcact ggttgcagtg gcatgccata cgctggccga
     7621 ttttgtcggt ttcctgattc ttggcgggtt gtcgatcatt gccgctatca cctacaccgt
     7681 gggcaatcgt ccttatggtt atatcggtct gggtgatatt tccgtactgg ttttctttgg
     7741 ctggttgagt gtcatgggga gctggtattt acaggctcat acattgattc cggcactgat
     7801 ccttccggcg accgcatgcg gcctgctggc aacggcagta ctgaatatta ataacctgcg
     7861 tgatatcaat agcgaccgcg aaaatggcaa aaacacgctg gtggtgcgct taggtgaagt
     7921 gaacgcgcgt cgttatcatg cctgcctgct gatgggctcg ctggtgtgtc tggcgctgtt
     7981 taatctcttt tcgctgcata gcctgtgggg ctggctgttc ctgctggcgg caccattact
     8041 ggtgaagcaa gcccgttatg tgatgcggga aatggacccg gtggcgatgc gaccaatgct
     8101 ggaacgtact gtcaagggag cgttactgac taacctgctg tttgttttag ggatattcct
     8161 aagccagtgg gcagcataac tgacaaatat caattaacaa ttgatgattt tgccaacagc
     8221 ccacatagcg cgatatactg aaaattctcg cagcaactga atgttaagcc tatgaaatac
     8281 gatacttccg agctttgtga catctatcaa gaagatgtta acgtcgtgga accgctgttc
     8341 tccaactttg gcggacgggc gtcgtttggc ggacaaataa tcacggtaaa atgtttcgag
     8401 gacaacgggt tgctgtacga tctgctcgaa cagaatggcc gtggtcgtgt tcttgtcgtc
     8461 gatggcggtg gttctgttcg tcgcgcactg gtcgatgctg aactggcgcg tctggcagta
     8521 caaaatgaat gggaaggtct ggtcatttac ggcgcggtgc gtcaggtaga tgacctggaa
     8581 gagttggata tcggcatcca ggcgatggcg gcaattccgg ttggtgccgc tggcgaaggc
     8641 attggcgaaa gcgatgtccg cgtcaatttt ggcggtgtca ccttcttctc cggcgaccat
     8701 ctttatgccg acaataccgg gattattctt tcagaagatc cgctggatat tgaatgataa
     8761 gaaaggcacc gcaaggtgcc ttttttctgc gttacctgtt ggcctacaca gtaaagaaat
     8821 tacgcggaag atgaagcgta atcagacctc ttccatgcga cccagcaggg cctgcagacg
     8881 ttcctgccag ccgttctgct gttctttcag atggttgttc tcacgctcca gctcttcgcg
     8941 ctgatgctgg gcattttgaa cttcctgcga cagtgagttg tttttttctt tcagctcttc
     9001 gatttccatc tgcaacagag tgatggtatc aatcgcctgc tgtacttttg cttccagttt
     9061 ctcaaacact tctaatgaca ttgtcatacc tctcctgaat tgcaaggcgt tgatggataa
     9121 aaatcctcgt cccgattacc ggtgacgcct taataaatac gagcgcactt tagttagctc
     9181 cgattgtatg aagccgcgcc atcgctgtcc agcggcacgc cttgcagatt acggtttgcc
     9241 acacttttca tccttctcct ggtgacataa tccacatcaa tcgaaaatgt taataaattt
     9301 gttgcgcgaa tgatctaaca aacatgcatc atgtacaatc agatggaata aatggcgcga
     9361 taacgctcat tttatgacga ggcacacaca ttttaagttc gatatttctc gtttttgctc
     9421 gttaacgata agtttacagc atgcctacaa gcatcgtgga ggtccgtgac tttcacgcat
     9481 acaacaaaca ttaactcttc aggatccgat tatgagtcaa acatcaacct tgaaaggcca
     9541 gtgcattgct gaattcctcg gtaccgggtt gttgattttc ttcggtgtgg gttgcgttgc
     9601 agcactaaaa gtcgctggtg cgtcttttgg tcagtgggaa atcagtgtca tttggggact
     9661 gggggtggca atggccatct acctgaccgc aggggtttcc ggcgcgcatc ttaatcccgc
     9721 tgttaccatt gcattgtggc tgtttgcctg tttcgacaag cgcaaagtta ttccttttat
     9781 cgtttcacaa gttgccggcg ctttctgtgc tgcggcttta gtttacgggc tttactacaa
     9841 tttatttttc gacttcgagc agactcatca cattgttcgc ggcagcgttg aaagtgttga
     9901 tctggctggc actttctcta cttaccctaa tcctcatatc aattttgtgc aggctttcgc
     9961 agttgagatg gtgattaccg ctattctgat ggggctgatc ctggcgttaa cggacgatgg
    10021 caacggtgta ccacgcggcc ctttggctcc cttgctgatt ggtctactga ttgcggtcat
    10081 tggcgcatct atgggcccat tgacaggttt tgccatgaac ccagcgcgtg acttcggtcc
    10141 gaaagtcttt gcctggctgg cgggctgggg caatgtcgcc tttaccggcg gcagagacat
    10201 tccttacttc ctggtgccgc ttttcggccc tatcgttggc gcgattgtag gtgcatttgc
    10261 ctaccgcaaa ctgattggtc gccatttgcc ttgcgatatc tgtgttgtgg aagaaaagga
    10321 aaccacaact ccttcagaac aaaaagcttc gctgtaatat gactacggga caattaaaca
    10381 tgactgaaaa aaaatatatc gttgcgctcg accagggcac caccagctcc cgcgcggtcg
    10441 taatggatca cgatgccaat atcattagcg tgtcgcagcg cgaatttgag caaatctacc
    10501 caaaaccagg ttgggtagaa cacgacccaa tggaaatctg ggccacccaa agctccacgc
    10561 tggtagaagt gctggcgaaa gccgatatca gttccgatca aattgcagct atcggtatta
    10621 cgaaccagcg tgaaaccact attgtctggg aaaaagaaac cggcaagcct atctataacg
    10681 ccattgtctg gcagtgccgt cgtaccgcag aaatctgcga gcatttaaaa cgtgacggtt
    10741 tagaagatta tatccgcagc aataccggtc tggtgattga cccgtacttt tctggcacca
    10801 aagtgaagtg gatcctcgac catgtggaag gctctcgcga gcgtgcacgt cgtggtgaat
    10861 tgctgtttgg tacggttgat acgtggctta tctggaaaat gactcagggc cgtgtccatg
    10921 tgaccgatta caccaacgcc tctcgtacca tgttgttcaa catccatacc ctggactggg
    10981 acgacaaaat gctggaagtg ctggatattc cgcgcgagat gctgccagaa gtgcgtcgtt
    11041 cttccgaagt atacggtcag actaacattg gcggcaaagg cggcacgcgt attccaatct
    11101 ccgggatcgc cggtgaccag caggccgcgc tgtttggtca gttgtgcgtg aaagaaggga
    11161 tggcgaagaa cacctatggc actggctgct ttatgctgat gaacactggc gagaaagcgg
    11221 tgaaatcaga aaacggcctg ctgaccacca tcgcctgcgg cccgactggc gaagtgaact
    11281 atgcgttgga aggtgcggtg tttatggcag gcgcatccat tcagtggctg cgcgatgaaa
    11341 tgaagttgat taacgacgcc tacgattccg aatatttcgc caccaaagtg caaaacacca
    11401 atggtgtgta tgtggttccg gcatttaccg ggctgggtgc gccgtactgg gacccgtatg
    11461 cgcgcggggc gattttcggt ctgactcgtg gggtgaacgc taaccacatt atacgcgcga
    11521 cgctggagtc tattgcttat cagacgcgtg acgtgctgga agcgatgcag gccgactctg
    11581 gtatccgtct gcacgccctg cgcgtggatg gtggcgcagt agcaaacaat ttcctgatgc
    11641 agttccagtc cgatattctc ggcacccgcg ttgagcgccc ggaagtgcgc gaagtcaccg
    11701 cattgggtgc ggcctatctc gcaggcctgg cggttggctt ctggcagaac ctcgacgagc
    11761 tgcaagagaa agcggtgatt gagcgcgagt tccgtccagg catcgaaacc actgagcgta
    11821 attaccgtta cgcaggctgg aaaaaagcgg ttaaacgcgc gatggcgtgg gaagaacacg
    11881 acgaataatg taaatgccga atgaagcgtt tatgccgcat ccggtagtcc cgaaacgtgc
    11941 gggggcaacc ccgcacacat caataatccc tcccttcccc tgtgctacac ttcgcgccat
    12001 tccttactgc ttagagtttg ctatgagacg agaacttgcc atcgaatttt cccgcgtcac
    12061 cgaatcagcg gcgctggctg gctacaaatg gttaggacgc ggcgataaaa acaccgcgga
    12121 cggcgcggcg gtaaacgcca tgcgtattat gctcaaccag gtcaacattg acggcaccat
    12181 cgtcattggt gaaggtgaaa tcgacgaagc accgatgctc tacattggtg aaaaagtcgg
    12241 tactggtcgc ggcgacgcgg tagatattgc tgttgatccg attgaaggca cgcgcatgac
    12301 ggcgatgggc caggctaacg cgctggcggt gctggcagta ggcgataaag gctgcttcct
    12361 caatgcgccg gatatgtata tggagaagct gattgtcggg ccgggagcca aaggcaccat
    12421 tgatctgaac ctgccgctgg cggataacct gcgcaatgta gcggcggcgc tcggcaaacc
    12481 gttgagcgaa ctgacggtaa cgattctggc taaaccacgc cacgatgccg ttatcgctga
    12541 aatgcagcaa ctcggcgtac gcgtatttgc tattccggac ggcgacgttg cggcctcaat
    12601 tctcacctgt atgccagaca gcgaagttga cgtgctgtac ggtattggtg gcgcgccgga
    12661 aggcgtagtt tctgcggcgg tgatccgcgc attagatggc gacatgaacg gtcgtctgct
    12721 ggcgcgtcat gacgtcaaag gcgacaacga agagaatcgt cgcattggcg agcaggagct
    12781 ggcacgctgc aaagcgatgg gcatcgaagc cggtaaagta ttgcgcctgg gcgatatggc
    12841 gcgcagcgat aacgtcatct tctctgccac cggtattacc aaaggcgatc tgctggaagg
    12901 cattagccgc aaaggcaata tcgcgactac cgaaacgctg ctgatccgcg gcaagtcacg
    12961 caccattcgc cgcattcagt ccatccacta tctggatcgc aaagacccgg aaatgcaggt
    13021 gcacatcctc tgattgattt gatcgattga gccttccagt ccttcgggac tggaattttt
    13081 ttgttcggag aacgaagata aggcaagtca atcaaaacag gagaaaaaca tggctgattg
    13141 ggtaacaggc aaagtcacta aagtgcagaa ctggaccgac gccctgttta gtctcaccgt
    13201 tcacgccccc gtgcttccgt ttaccgccgg gcaatttacc aagcttggcc ttgaaatcga
    13261 cggcgaacgc gtccagcgcg cctactccta tgtaaactcg cccgataatc ccgatctgga
    13321 gttttacctg gtcaccgtcc ccgatggcaa attaagccca cgactggcgg cactgaaacc
    13381 aggcgatgaa gtgcaggtgg ttagcgaagc ggcaggattc tttgtgctcg atgaagtgcc
    13441 gcactgcgaa acgctatgga tgctggcaac cggtacagcg attggccctt atttatcgat
    13501 tctgcaacta ggtaaagatt tagatcgctt caaaaatctg gtcctggtgc acgccgcacg
    13561 ttatgccgcc gacttaagct atttgccact gatgcaggaa ctggaaaaac gctacgaagg
    13621 aaaactgcgc attcagacgg tggtcagtcg ggaaacggca gcggggtcgc tcaccggacg
    13681 gataccggca ttaattgaaa gtggggaact ggaaagcacg attggcctgc cgatgaataa
    13741 agaaaccagc catgtgatgc tgtgcggcaa tccacagatg gtgcgcgata cacaacagtt
    13801 gctgaaagag acccggcaga tgacgaaaca tttacgtcgc cgaccgggcc atatgacagc
    13861 ggagcattac tggtaagcgg ttacttatcg ataaacggca cgatgagcaa atccgcactc
    13921 atcttattga tcatcccgcg atatgccggc atcaaacggt tgataaatga gtgatgatga
    13981 ccacagacaa ggaggtcgca ctgctctttt tgcataattt ccagcagtgt ttccggcatt
    14041 tctccgcgtt caatacgcag ttttgtcttc ggccattgaa tatttttcgt cagtttatac
    14101 agcttgttat ccgacttatt cttcaacaat tgaagaatat cttctgttgc agggaagtag
    14161 atacccggat acaactcgct taagccatca tcaatatgaa ttaacgtcag gtgagcgtca
    14221 ttatgtctgg cgagctccag ggctttattc accagtaagg catcttcttc attcccggaa
    14281 attgccacgc caatgtgttt ataagccatg tttaactcct tctaaagcaa ctccatcaag
    14341 ctaacgaacg cagtgataac tcaaaaataa tcatctcggc ctggcatgag aaagtgaagg
    14401 ccgcatcaag ctcaacttgc ccctccagct ccttaatctt ataggccacg ctggcccctt
    14461 catctgcaga ggatgtagcg gcggcaagct ctttcagttt ggtcataaaa gactctgctt
    14521 cttcgcgggt ggcaaaaaag cgcgaaaact tactggtaca gttgtcgtta tcaatcaccg
    14581 taccgatatc aatcgcacat cctttagtac tgcatttatc tacgacatct ttcatagggc
    14641 acctctgtat attcgcctct ctgtcgatta cgacttaaga ataatgcgcc gttaagggaa
    14701 gaacaaacaa gtaatgatct tatggattac catttttttt gatattgctt aaggtgaaga
    14761 gttcagaagg attttccggg tattgtcatt tgcatcgtgg aaataacaat cccggaaaaa
    14821 aatagcagta agagatatat taaaggttaa ttacttgatt tattgtcggc tttatacttc
    14881 acatcctgag tatctttacc atatttattt tcgccttgtg tgccaacaaa cgcaccaaga
    14941 tcgataagca tcatcaccag aatcaacgtc gggacaaaac gccccaccgc ccattgccag
    15001 acacccggta aaatcgccca gttacccgcc agcagcatcc acgccacaat catcagaaat
    15061 gcccatgcgc cggaacgccc gcgatcatgc aagcgcttaa cagttactgc cgctgttggc
    15121 cagagcaagc acacaaggca aaacgccgcg gtctgaatat cgagtagatt cttacccgcc
    15181 agtgagaaaa gcaccagcat gcctgcgaac cacaggccta tccaaatcca gaaatcacgg
    15241 cgtccaatac gccctttaaa tgagaataac cattgctgta tggtcatgta agttccttga
    15301 tggttgtctt ttccaggatt ctaccctttt gacaagggcg acagatatcg ttttaatcgg
    15361 agccagtcat aacaaaaggt actgtcaatg aagccagggt gtacgctgtt ttttctctta
    15421 tgttctgcat taaccgttac aacagcggcg catgcacaaa caccagatac ggcaacgacc
    15481 gcgccttatc tgctggctgg agcccctact ttcgatctct ccatcagcca gtttcgagaa
    15541 gactttaaca gccagaatcc cagcctgcca ctgaacgaat ttcgtgccat cgacagcagt
    15601 cccgacaaag ccaatctcac tcgtgctgca agtaaaatta atgagaactt gtatgcttct
    15661 acagcgctgg agcgcggtac cttaaaaatc aaaagcattc aaatgacctg gctacccatc
    15721 caggggccag agcaaaaagc cgcgaaagcg aaagctcagg aatacatggc agcggtgatc
    15781 cgcacactca ccccattaat gaccaaaaca caaagccaga aaaaactgca gtcgctacta
    15841 acggcgggga aaaacaaacg ttattacacc gagacagaag gtgcactgcg ttatgttgtc
    15901 gcggacaacg gcgaaaaggg gctgaccttc gctgttgaac cgattaagct ggcgctatct
    15961 gaatcgcttg aaggtttgaa taaatgacaa aaagcaaagc ctttgtgccg atgaatctct
    16021 atactgtttc acagacctgc tgccctgcgg ggcggccatc ttcctttatt cgcttataag
    16081 cgtggagaat taaaatgcga catcctttag tgatgggtaa ctggaaactg aacggcagcc
    16141 gccacatggt tcacgagctg gtttctaacc tgcgtaaaga gctggcaggt gttgctggct
    16201 gtgcggttgc aatcgcacca ccggaaatgt atatcgatat ggcgaagcgc gaagctgaag
    16261 gcagccacat catgctgggt gcgcaaaacg tggacctgaa cctgtccggc gcattcaccg
    16321 gtgaaacctc tgctgctatg ctgaaagaca tcggcgcaca gtacatcatc atcggtcact
    16381 ctgaacgtcg tacttaccac aaagaatctg acgaactgat cgcgaaaaaa ttcgcggtgc
    16441 tgaaagagca gggcctgact ccggttctgt gcatcggtga aaccgaagct gaaaatgaag
    16501 cgggcaaaac tgaagaagtt tgcgcacgtc agatcgacgc ggtactgaaa actcagggtg
    16561 ctgcggcatt cgaaggtgcg gttatcgctt acgaacctgt atgggcaatc ggtactggca
    16621 aatctgcaac tccggctcag gcacaggctg ttcacaaatt catccgtgac cacatcgcta
    16681 aagttgacgc taacatcgct gaacaagtga tcattcagta cggcggctct gtaaacgcgt
    16741 ctaacgctgc agaactgttt gctcagccgg atatcgacgg cgcgctggtt ggtggtgctt
    16801 ctctgaaagc tgacgccttc gcagtaatcg ttaaagctgc agaagcggct aaacaggctt
    16861 aagtctgaca ggtgccggat ttcatatccg gcacttactt tccttaactc ttcgccttaa
    16921 cgcaaaatct cacactgatg atcctgaatt tcctcggctg aagcacggtt aagcgtcagt
    16981 agatttcgtt gtgtcgccag caatacaaat gagttatcac tctgccgtac catcgccagc
    17041 ccgtagcgtc ccatatgttc ccgcgcctca ggtacttctt ctgccagcat cataaatggg
    17101 ctgcgttgta ccagttcgct ttccgttacc cgacgcgcca ggtattcatg cccgcgcaaa
    17161 ccacctggca gtggcaacca gcggctgctg atgttcgcca gattgttatc cagctgttcg
    17221 cgcacatcag gacgaataca agagatatga atatgaaaat ggttttgcgt acgcccggtg
    17281 cgggagttga tcgccaaaga aaccgcgcga tcgggaaccg gctggccgta ttttttgctc
    17341 ataaaatcac gcgcctgcca agccaaccaa aagaagttcg gcgttgaagg atcggtcaac
    17401 aaaggacttt cagtaccgtt aatacgatac gttggcatca acagatattg cagtgggcca
    17461 ttaagatctt ttaaaaccac gtatccggca ttgggtttga cttccgcaca tggcgaagga
    17521 ttttgatttt gctgctgatt gggcaaacat tcctcaagga caatcttacg taatgtatcc
    17581 gactcttcac cggttaattt ccagtaacca ataccggcag ccacaacggc gataactatc
    17641 atcaccaaaa aaagaagacc cgcttttttc atcttttttt ccctgtacct caaagagatg
    17701 caagggtaac gcaaaatcgt gacaaataaa aaacccggtc gcgagaaacc accgggtttg
    17761 ataattatcc tggggaaatc agcgtttgct gatctgatcg aacgtaccgc cgttagcaaa
    17821 atgctctttt tgcgctttcg tccagccgcc gaactcttca tcaatggtga ataacttcag
    17881 ctttggaaac gcattttcgt actttttcgc cacctcagcg tcgcgcggac ggtagtagtt
    17941 tttcgcggca atttcctgac cttctggcga gtagagatat ttcaggtagg cttccgccac
    18001 ctctttagta ccttttttct cgaccacttt atcgaccacc gacacggttg gctctgcgag
    18061 gatagactca ctcggcgtga cgatttcgaa tttatctttc cccagttcat tcgctgccag
    18121 cagagcttcg ttttcccagg caatcagtac atcgccaatt ccgcgctcga caaaagtgtt
    18181 agtggagcca cgcgcgccag aatccagaac ttcgacgttt ttatacagtg cccgaacaaa
    18241 atcctgtgct tttgcctgat cgttgttgtt gtgatgcagc gcgtagcccc aggctgccag
    18301 gtagttccag cgcgcgccac cagagctttt cggattaggc gtgatcaccg aaacacccgg
    18361 tttaatcaga tcgttccagt catggatctg cttcggattt cccttacgta ccaggaaaac
    18421 aatggtggaa gtgtacggtg cggagttatc cggcagacgt ttgatccact ctttatcaat
    18481 ccgcccgcgt tccgcaattg cgtccacgtc ataggccaga gccagcgtga caacatcagc
    18541 ttcaataccg ttgattaccg acgtcgcttg tttacctgag ccaccgtgtg actgacgaat
    18601 caccacgtta tcaccagttt gctgtttcca gtgggcgctg aatgccttgt tgtactgttc
    18661 gtacaattcg cgcgttggat catatgaaac gttaagaagc tgaatatcct ttgccataac
    18721 gctggttgcc gccagcaaaa atgttaaccc tacgccccac ttgttcatcg cccgactctc
    18781 ttatgttgtg ttgtgatgag caaagcgtgc cagaaggtta accaaacatt aaagaataaa
    18841 aaaagattgg ctataacttg cgggtatatg ttgggggatt aaaaaggcgg aagaaatccg
    18901 cctcatattg ctgacaaagt gcgctttgtc catgccggat gcggcgcgaa cgccttatcc
    18961 ggcctacaaa agtttgcaaa ttcaataaat tgcagaattc atgtaggcct gataagcgaa
    19021 gcgcatcagg catttttgct tctgtcatcg gtttcaggct aaaggaatct gcctttttcc
    19081 gaaatcatta atacagtttt ttcgcgcagt ccagccagtc acctttgaac ggacgcttca
    19141 tgttttcgat agcgtcgatg atgtcgtggt gaaccagctg ttcgttctgg atacctacac
    19201 aacgaccgcc gtaacctgcc agcagcagat cgatagcgta agcgcccata cgggaagcca
    19261 gaatacggtc gtaaggcacc ggagaaccac cgcgctggat gtggcccagc acagttgcgc
    19321 gggtttcacg accggtttct ttctcgatga aatgcgccag ttcgtcaaca tcacacatat
    19381 gttcggtaat cgccacgatc gcgtgttttt tacctttcgc gatacccgct ttgatttcgt
    19441 ttaccaggtc ttcacggctg aattcaactt ccggaaccac aacgaattca cagccaccgg
    19501 caatggccgc agccagggtc agatcgccac aataacggcc catcacttcc accacggaaa
    19561 tacgctggtg agaagaagag gtgtcacgca gacggtcgat cgcttctaca acggtgctca
    19621 gcgcagtgaa gaaaccgata gtgtagtcag tgcctttgat gtcgttgtcg atagtgcccg
    19681 gcaggccgat gcacgggaag cccatttcgg tcagacgcat tgcacccatg taggaaccgt
    19741 caccgccgat aaccaccagc gcgtcgatcc cacgtttttt caggttttcg atagccacgg
    19801 cgcggatgtt ctcgtcgcgg aattccggga aacgcgcaga accgaggaac gtaccgccac
    19861 ggttgatcat gtcagacacg ctgtaacggt ctagctgtac catacggtct tcatacagac
    19921 ccagatagcc gtcataaatg cccattactt ccagaccttc tgtcagcgca gaacgaacaa
    19981 ccccgcgaat tgcggcgttc atgcctggcg catcaccgcc gcttgtcaac acaccgattt
    20041 tcttaatcat gactacctct gaactttgga atgcaaaata aaatctgttg ccggaagtct
    20101 tcttgcacat cgaagtgatc caacgaatgt gcaaatagta taacaatcac ttcctgctga
    20161 attgattcag gtcaggccaa atggcggtat tttatacaca aaatgcgggt ctggctctct
    20221 tttatactga ttatgaaagc atagaccgtt taccctccct gggtacgacg gaacaggggt
    20281 cctgatggat aattacatcc gatcccggaa aacgccgtaa aatagcctgc tctacctgat
    20341 ccgccaccat atgtgcctga accaaaggca gagagtcttc catttccaaa tgaatctgaa
    20401 taaagcgggt cggccctgac tgccgcgtgc gaagatcgtg agcgccgcta acacccggcc
    20461 aggaagtcac gatatcaata atttcttgcc gttcctcatc aggcaatgcg cgatccagta
    20521 atgactgtac cgcctcatat cccatgcgta acgcgctata taaaatatag atgccgattc
    20581 ccaatgcaaa cagagcatcg gcgcgatgcc agccgtacca ggacaacccc agcgccagca
    20641 gaattgcgcc gttcatcata acatcagact ggtaatgtag catatcagcc cgcaccgcct
    20701 ggctttgcgt ccgccgcacc acccaacgct gaaacgagac aaggataatc gtacaaatta
    20761 gcgccacaat tgtcacgata accccgacgc ctggatctgt catcggtgtt ggagatatca
    20821 gatgttgaat acccgtcaaa aacaggaata gtgccgaacc ggagataaac atactttgcg
    20881 ccagcgccgc gagggactct gctttaccgt gaccaaacga gtgattatcg tcggcaggtt
    20941 gcagggaata tcgcaccacc agtaaattcg tcaacgacgc gccgatatcc accagcgaat
    21001 ccaccagcgc ggcgagaata ctcaccgacc cggtatacca ccatgcaaaa attttaatca
    21061 gcaatagcaa cgaagccatc gccgtcgcag caatcgccgc ccgactgacc agccgtccat
    21121 aagattgatt cataaatact cccgctatca actgacgcta gtataacgga agcaaatcat
    21181 ctgcaatgca ttaagcagca ggcaaattga ggataaaaaa aacccccaca tcatgtgggg
    21241 gaagacaggg atggtgtcta tggcaaggaa aacagggttt actactggga acgtgagttg
    21301 ctactactca atagcttcaa cgatgaactt ttttgccatt gcgtcacgtc gcgcaactgc
    21361 tccattcgtt gttgatgttt ctcgtttaaa accgcttgct gctccggcgt taacaggcga
    21421 tacatttggt tgcggacttt tgccatctca acctgacgag caatttgctc attcgccatt
    21481 ttttctgcct gtgcgcgcac agcgttttca tcaaaatttt ctgcggtgac aaggcgatgc
    21541 attgtctcca gttcgctaac attaacagga ggctgttcgt gccgggcctg ttgcataaga
    21601 tctcgcatct gctgacgctg atgttcggtt aaacttatgc cgtcgaacat atggctctgc
    21661 gtactgcgct gcgtaagttc ttcacccgga tgccagttat cgcctgaacc gacttcagca
    21721 gcgtggctta atgaactgac tgccagcgtt gaggccatga cggcagcggt aactatgcgc
    21781 atcatttgct cccaaaatct ttctgtcgcg attcaacgat agagagttta cgattcaggc
    21841 tgcaaacatg cgtcaggggg tgtaaaacaa cgtaaagtca tggattagcg acgtctgatg
    21901 acgtaatttc tgcctcggag gtatttaaac aatgaataaa atcctgttag ttgatgatga
    21961 ccgagagctg acttccctat taaaggagct gctcgagatg gaaggcttca acgtgattgt
    22021 tgcccacgat ggggaacagg cgcttgatct tctggacgac agcattgatt tacttttgct
    22081 tgacgtaatg atgccgaaga aaaatggtat cgacacatta aaagcacttc gccagacaca
    22141 ccagacgcct gtcattatgt tgacggcgcg cggcagtgaa cttgatcgcg ttctcggcct
    22201 tgagctgggc gcagatgact atctcccgaa accgtttaat gatcgtgagc tggtggcacg
    22261 tattcgcgcg atcctgcgcc gttcgcactg gagcgagcaa cagcaaaaca acgacaacgg
    22321 ttcaccgaca ctggaagttg atgccttagt gctgaatcca ggccgtcagg aagccagctt
    22381 cgacgggcaa acgctggagt taaccggtac tgagtttacc ctgctctatt tgctggcaca
    22441 gcatctgggt caggtggttt cccgtgaaca tttaagccag gaagtgctgg gcaaacgcct
    22501 gacgcctttc gaccgcgcta tcgatatgca catttccaac ctgcgtcgta aactgccgga
    22561 tcgtaaagat ggtcacccgt ggtttaaaac cttgcgtggt cgcggctacc tgatggtttc
    22621 tgcttcatga taggcagctt aaccgcgcgc atcttcgcca tcttctggct gacgctggcg
    22681 ctggtgttga tgttggtttt gatgttaccc aagctcgatt cacgccagat gaccgagctt
    22741 ctggatagcg aacagcgtca ggggctgatg attgagcagc atgttgaagc ggagctggcg
    22801 aacgatccgc ccaacgattt aatgtggtgg cggcgtctgt tccgggcgat tgataagtgg
    22861 gcaccgccag gacagcgttt gttattggtg accaccgaag gccgcgtgat cggcgctgaa
    22921 cgcagcgaaa tgcagatcat tcgtaacttt attggtcagg ccgataacgc cgatcatccg
    22981 cagaagaaaa agtatggccg cgtggaactg gtcggtccgt tctccgtacg tgatggcgaa
    23041 gataattacc aactttatct gattcgtccg gccagcagtt ctcaatccga tttcattaac
    23101 ttactgtttg accgcccgct attactgctg attgtcacca tgttggtcag tacgccgctg
    23161 ctgttgtggt tggcctggag tctggcaaaa ccggcgcgta agctgaaaaa cgctgccgat
    23221 gaagttgccc agggaaactt acgccagcac ccggaactgg aagcggggcc acaggaattc
    23281 cttgccgcag gtgccagttt taaccagatg gtcaccgcgc tggagcgcat gatgacctct
    23341 cagcagcgtc tgctttctga tatctctcac gagctgcgca ccccgctgac gcgtctgcaa
    23401 ctgggtacgg cgttactgcg ccgtcgtagc ggtgaaagca aggaactgga gcgtattgaa
    23461 accgaagcgc aacgtctgga cagcatgatc aacgatctgt tggtgatgtc acgtaatcag
    23521 cagaaaaacg cgctggtaag cgagacattg aaagctaacc agttgtgggg cgaagtgctg
    23581 gataacgcgg cgttcgaagc agaacagatg ggcaagtcgt tttctgttaa cttcccgcct
    23641 gggccgtggc cgctgtacgg caatccgaac gccctggaaa gtgcgctgga aaacattgtt
    23701 cgtaatgctc tgcgttattc ccatacgaag attgaagtgg gctttgcggt agataaagac
    23761 ggtatcacca ttacggtgga cgacgatggt cctggcgtta gcccggaaga tcgcgaacag
    23821 attttccgtc cgttctatcg gaccgatgaa gcacgcgatc gtgaatctgg cggtacagga
    23881 ttggggctgg cgattgttga aaccgccatt cagcagcatc gtggctgggt gaaggcagaa
    23941 gacagcccgc tgggcggttt acggctggtg atttggttgc cgctgtataa gcggagttaa
    24001 actccgcatt tgtaggcagg ataaggcgtt tacgccgcat ccggcatttg agcaggatgc
    24061 ctgatgcgac gctgatagcg tcttatcagg cctacactcc gggggttatt ttccccacaa
    24121 ccgccgggaa aaatcttcga tcttgccgct cagtcggcgc ttttgcatcg ttcgcgtcca
    24181 gcttttcgat aacccggcag cggagagtaa acggtgatac tgatcgtcat caaacggcat
    24241 atgccatgcg atggcggcag cctcctgcac ggtcacatcg ctgacacggg aaaccaactc
    24301 cagcggcgcg tccgcagaca ctttccctgg cgctatcacg ctatacaacc atcccacttt
    24361 acccgtgttt tgcatcaact gcgctatatc gctgatatca aaatggtaat tgagtttata
    24421 gcaaggcgag cgcggctggc tgacctgaat taatgcctct ccccagcgga aaatatcgcc
    24481 catataaaca ttactttccg tcaggccgtc ggttgagagg ttttcaccaa acgcaggcgc
    24541 aacaaacaac tccgcctgtt ccggaaattc ccgcgcccag tagagataat gctcacgagg
    24601 ataatgacac agcgctctgt ctggcccgcc gtgaaccttt ttctccgcct gctcgtcacc
    24661 ttccagcccc agctccgtca gcatcaactc accatcaacc tggattttag caattgcgct
    24721 gggtttgcct tcgggataag cctgaatctt gcctgtgtat acatcaaccg gatatcgcat
    24781 ctgttccctc tccacgagaa atttccccat tagaccatat ttattttatg tcaggcgtgc
    24841 tgttttcgcg gtaagtatcc aggcaggaac tcaatagcaa accggacgaa cgttagttca
    24901 tccggctgtg gggattaagg aagcaggttt atttcaccgt acctaaaatt tcgattttcg
    24961 ctgctctggc tttgacttta cgtgaccaaa tagaggtaag aattggcacc agaatcgaag
    25021 tcacaatgac cgccgtcgct accagcgaag ttgctgccgg agccatcggt ttaaacgcag
    25081 gcaccatttc tgcaatcagc acaggtgtcg ctaccgcggc ccctgcggaa ctggaagcgg
    25141 caattccggc agtgccatcg ccaccgccaa tcaatttatc ggcgataatc aacggaatac
    25201 cggtcacgat aattactgcc acacccaaca ggatccccag caaaccagtc tgggcaatca
    25261 cagtcaaatc aatggtattg cccagcgcga aggcaaagaa tggaatcagc gtttgcaccg
    25321 ctttgctgaa aaattctcgt aattcagggt caaggttccc cagggcaaag cccaccagga
    25381 acggtaatac tgcgccgacg aaaacatgcg gttcaaacga ggcaatcccg gcagtgccca
    25441 gaataatcat cgtcatgagc ggcccggact ccaacgacat caacacaaat gccccagctt
    25501 cttctttcgt accgtactgc tgcatgatgg aagcgtaaag tccgccgttg gtcatatcca
    25561 tcgccgccac cagcgccagc gttgaaagtc cggcaaagaa tccaacttca acaccatgtt
    25621 ccggaataat acgcgaggca attgccgcaa ccacccacgc gacggcaatt ttagttacca
    25681 ccagcgtacc ggatttacgc agtaccgttc ccgtcgcgct taattttatt gacgccccca
    25741 tgcaaaaaaa ccacaccgcc agaatgggca ccgtaccggt aatcatcccg ttggtgaatg
    25801 ctccaaaata tttccccgcc cccggcgaga aggtgtggca cagtgcgcca aggaatagcg
    25861 ggacgagcat catccccccc gggattttct caatcgagcg ttttatctgc atttccatca
    25921 cctgtcggca tatttttaag ggctgatgcg taattcctca atggagcatc agtgttgatg
    25981 gaaacgaaga tagacattca tttaatcaat aaaagtgatc aaaaccacat caattgaaac
    26041 actgttttat ttttatcgga tcattgtttt tattttgaaa ttgatcacaa aaaaaccacc
    26101 gcagttggcg atggttcatt ttttaagctg atatgcggcc tatacgcctc attgcagcag
    26161 gcggcaaatg attatttttt cgccgcaaaa cgtgccgctg cttcgtccca gttcaccacg
    26221 ttccagaact ctttaatgta gtccggacgg cggttctgga atttcaggta gtaagcatgt
    26281 tcccacacat ccaggcccag aatcgggaag ccggaagcgc cagaaatagc ttcacccatc
    26341 agcggagaat cctggttagc agtagaaacc accgccagtt tatcgccttt cagcaccagc
    26401 catgcccagc cggaaccaaa gcgggaagct gccgcttttt caaattctgc tttgaagtta
    26461 tcaacggagc cgaagtcacg ttcgatagcc gctttcaggt caccctgcag ggtggtgcct
    26521 tttttcagac ctttccagaa caggctgtgg ttagcgtgac cgccagcgtt gttgcgcagt
    26581 acggttttct tgtctgctgg cagctggtcc agtttggtga tcagctcttc aaccggcagg
    26641 ttggcaaatt ctggcaggct ttccagcgcc gcgttggcgt tgtttacgta ggtctgatgg
    26701 tgtttggtgt ggtggatttc catggtctgc ttatcgaagt gcggttccag ggcatcgtaa
    26761 gcatacggca gggatggcag ggtatagctc atattcatct ccagtattgt cgggcggccg
    26821 attgttaatg ccgcgtaagc agttggttca ttatagttaa ttaaatgata ttgaaaatga
    26881 ttatcaatgc cgtacttttc gtaagggtat ggttttgcag gaaaatgccc gagatgtgaa
    26941 gcaaatcacc cacttaatgc cgtgattgcc agtaaatcga caacggcggc aacaggcgaa
    27001 aggttaatcg acagcacgat ttttacactc atctcgtcgg agatgtgacg cgacgaaaaa
    27061 tgatgaggat aagaagatga gtaacgcgat tacgatgggg atattttggc atttgatcgg
    27121 cgcggccagt gcagcctgtt tttacgctcc gttcaaaaaa gtaaaaaaat ggtcatggga
    27181 aaccatgtgg tcagtcggtg ggattgtttc gtggattatt ctgccgtggg ccatcagcgc
    27241 cctgttacta ccgaatttct gggcgtatta cagctcgttt agtctctcta cgctactgcc
    27301 tgtttttctg ttcggcgcta tgtgggggat cggtaatatc aactacggcc tgaccatgcg
    27361 ttatctcggc atgtcgatgg gaattggcat cgccattggc attacgttga ttgtcggtac
    27421 gctgatgacg ccaattatca acggcaattt cgatgtgttg attagcaccg aaggcggacg
    27481 catgacgttg ctcggcgttc tggtggcgct gattggcgta gggattgtaa ctcgcgccgg
    27541 gcagttgaaa gagcgcaaga tgggcattaa agccgaagag ttcaatctga aaaaagggct
    27601 ggtgctggcg gtgatgtgcg gcattttctc tgccgggatg tcctttgcga tgaacgccgc
    27661 aaaaccgatg catgaagccg ctgccgcact tggcgtcgat ccactgtatg tcgctctgcc
    27721 aagctatgtt gtcatcatgg gcggcggcgc gatcattaac ctcggtttct gttttattcg
    27781 tctggcaaaa gtgaaggatt tgtcgctaaa agccgacttc tcgctggcaa aatcgctgat
    27841 cattcacaat gtgttactct cgacactggg cgggttgatg tggtatctgc aattcttttt
    27901 ctatgcctgg ggccacgccc gcattccggc gcagtatgac tacatcagtt ggatgctgca
    27961 tatgagtttc tatgtattgt gcggcggtat cgtcgggctg gtgctgaaag agtggaacaa
    28021 tgcaggacgc cgtccggtaa cggtgttgag cctcggttgt gtggtgatta ttgtcgccgc
    28081 taacatcgtc ggcatcggca tggcgaatta atctttctgc gaattgagat gacgccactg
    28141 gctgggcgtc atcccggttt cccgggtaaa caccaccgaa aaatagttac tatcttcaaa
    28201 gccacattcg gtcgaaatat cactgattaa caggcggcta tgctggagaa gatattgcgc
    28261 atgacacact ctgacctgtc gcagatattg attgatggtc attccagtct gctggcgaaa
    28321 ttgctgacgc aaaacgcgct cactgcacga tgcctcatca caaaatttat ccagcgcaaa
    28381 gggacttttc aggctagccg ccagccgggt aatcagctta tccagcaacg tttcgctgga
    28441 tgttggcggc aacgaatcac tggtgtaacg atggcgattc agcaacatca ccaactgccc
    28501 gaacagcaac tcagccattt cgttagcaaa cggcacatgc tgactacttt catgctcaag
    28561 ctgaccgata acctgccgcg cctgcgccat ccccatgcta cctaagcgcc agtgtggttg
    28621 ccctgcgctg gcgttaaatc ccggaatcgc cccctgccag tcaagattca gcttcagacg
    28681 ctccgggcaa taaataatat tctgcaaaac cagatcgtta acggaagcgt aggagtgttt
    28741 atcgtcagca tgaatgtaaa agagatcgcc acgggtaatg cgataagggc gatcgttgag
    28801 tacatgcagg ccattaccgc gccagacaat caccagctca caaaaatcat gtgtatgttc
    28861 agcaaagaca tcttgcggat aacggtcagc cacagcgact gcctgctggt cgctggcaaa
    28921 aaaatcatct ttgagaagtt ttaactgatg cgccaccgtg gctacctcgg ccagagaacg
    28981 aagttgatta ttcgcaatat ggcgtacaaa tacgttgaga agattcgcgt tattgcagaa
    29041 agccatcccg tccctggcga atatcacgcg gtgaccagtt aaactctcgg cgaaaaagcg
    29101 tcgaaaagtg gttactgtcg ctgaatccac agcgataggc gatgtcagta acgctggcct
    29161 cgctgtggcg tagcagatgt cgggctttca tcagtcgcag gcggttcagg tatcgctgag
    29221 gcgtcagtcc cgtttgctgc ttaagctgcc gatgtagcgt acgcagtgaa agagaaaatt
    29281 gatccgccac ggcatcccaa ttcacctcat cggcaaaatg gtcctccagc caggccagaa
    29341 gcaagttgag acgtgatgcg ctgttttcca ggttctcctg caaactgctt ttacgcagca
    29401 agagcagtaa ttgcataaac aagatctcgc gactggcggt cgagggtaaa tcattttccc
    29461 cttcctgctg ttccatctgt gcaaccagct gtcgcacctg ctgcaatacg ctgtggttaa
    29521 cgcgccagtg agacggatac tgcccatcca gctcttgtgg cagcaactga ttcagcccgg
    29581 cgagaaactg aaatcgatcc ggcgagcgat acagcacatt ggtcagacac agattatcgg
    29641 tatgttcata cagatgccga tcatgatcgc gtacgaaaca gaccgtgcca ccggtgatgg
    29701 tatagggctg cccattaaac acatgaatac ccgtgccatg ttcgacaatc acaatttcat
    29761 gaaaatcatg atgatgttca ggaaaatccg cctgcgggag ccggggttct atcgccacgg
    29821 acgcgttacc agacggaaaa aaatccacac tatgtaatac ggtcatactg gcctcctgat
    29881 gtcgtcaaca cggcgaaata gtaatcacga ggtcaggttc ttaccttaaa ttttcgacgg
    29941 aaaaccacgt aaaaaacgtc gatttttcaa gatacagcgt gaattttcag gaaatgcggt
    30001 gagcatcaca tcaccacaat tcagcaaatt gtgaacatca tcacgttcat ctttccctgg
    30061 ttgccaatgg cccattttcc tgtcagtaac gagaaggtcg cgaattcagg cgctttttag
    30121 actggtcgta atgaaattca gcaggatcac attatgacct ttcgcaattg tgtcgccgtc
    30181 gatctcggcg catccagtgg gcgcgtgatg ctggcgcgtt acgagcgtga atgccgcagc
    30241 ctgacgctgc gcgaaatcca tcgttttaac aatgggctgc atagtcagaa cggctatgtc
    30301 acctgggatg tggatagcct tgaaagtgcc attcgccttg gattaaacaa ggtgtgcgag
    30361 gaagggattc gtatcgatag cattgggatt gatacctggg gcgtggactt tgtgctgctc
    30421 gaccaacagg gtcagcgtgt gggcctgccc gttgcttatc gcgatagccg caccaatggc
    30481 ctaatggcgc aggcacaaca acaactcggc aaacgcgata tttatcaacg tagcggcatc
    30541 cagtttctgc ccttcaatac gctttatcag ttgcgtgcgc tgacggagca acaacctgaa
    30601 cttattccac acattgctca cgctctgctg atgccggatt acttcagtta tcgcctgacc
    30661 ggcaagatga actgggaata taccaacgcc acgaccacgc aactggtcaa tatcaatagc
    30721 gacgactggg acgagtcgct actggcgtgg agcggggcca acaaagcctg gtttggtcgc
    30781 ccgacgcatc cgggtaatgt cataggtcac tggatttgcc cgcagggtaa tgagattcca
    30841 gtggtcgccg ttgccagcca tgataccgcc agcgcggtta tcgcctcgcc gttaaacggc
    30901 tcacgtgctg cttatctctc ttctggcacc tggtcattga tgggcttcga aagccagacg
    30961 ccatttacca atgacacggc actggcagcc aacatcacca atgaaggcgg ggcggaaggt
    31021 cgctatcggg tgctgaaaaa tattatgggc ttatggctgc ttcagcgagt gcttcaggag
    31081 cagcaaatca acgatcttcc ggcgcttatc tccgcgacac aggcacttcc ggcttgccgc
    31141 ttcattatca atcccaatga cgatcgcttt attaatcctg agacgatgtg cagcgaaatt
    31201 caggctgcgt gtcgggaaac ggcgcaaccg atcccggaaa gtgatgctga actggcgcgc
    31261 tgcattttcg acagtctggc gctgctgtat gccgatgtgt tgcatgagct ggcgcagctg
    31321 cgcggtgaag atttctcgca actgcatatt gtcggcggag gctgccagaa cacgctgctc
    31381 aaccagctat gcgccgatgc ctgcggtatt cgggtgatcg ccgggcctgt tgaagcctcg
    31441 acgctcggca atatcggcat ccagttaatg acgctggatg aactcaacaa tgtggatgat
    31501 ttccgtcagg tcgtcagcac caccgcgaat ctgaccacct ttacccctaa tcctgacagt
    31561 gaaattgccc actatgtggc gcagattcac tctacacgac agacaaagga gctttgcgca
    31621 tgaccactca actggaacag gcctgggagc tagcgaaaca gcgtttcgcg gcggtgggga
    31681 ttgatgtcga ggaggcgctg cgccaacttg atcgtttacc cgtttcaatg cactgctggc
    31741 agggcgatga tgtttccggt tttgaaaacc cggaaggttc gctgaccggg gggattcagg
    31801 ccacaggcaa ttatccgggc aaagcgcgta atgccagtga gctacgtgcc gatctggaac
    31861 aggctatgcg gctgattccg gggccgaaac ggcttaattt acatgccatc tatctggaat
    31921 cagatacgcc agtctcgcgc gaccagatca aaccagagca cttcaaaaac tgggttgaat
    31981 gggcgaaagc caatcagctc ggtctggatt ttaacccctc ctgcttttcg catccgctaa
    32041 gcgccgatgg ctttacgctt tcccatgccg acgacagcat tcgccagttc tggattgatc
    32101 actgcaaagc cagccgtcgc gtttcggcct attttggcga gcaactcggc acaccatcgg
    32161 tgatgaacat ctggatcccg gatggtatga aagatatcac cgttgaccgt ctcgccccgc
    32221 gtcagcgtct gctggcagca ctggatgagg tgatcagcga gaagctaaac cctgcgcacc
    32281 atatcgacgc cgttgagagc aaattgtttg gcattggcgc agagagctac acggttggct
    32341 ccaatgagtt ttacatgggg tatgccacca gccgccagac tgcgctgtgc ctggacgccg
    32401 ggcacttcca cccgactgaa gtgatttccg acaagatttc cgccgccatg ctgtatgtgc
    32461 cgcagttgct gctgcacgtc agccgtccgg ttcgctggga cagcgatcac gtagtgctgc
    32521 tggatgatga aacccaggca attgccagtg agattgtgcg tcacgatctg tttgaccggg
    32581 tgcatatcgg ccttgacttc ttcgatgcct ctatcaaccg cattgccgcg tgggtcattg
    32641 gtacacgcaa tatgaaaaaa gccctgctgc gtgcgttgct ggaacctacc gctgagctgc
    32701 gcaagctgga agcggcgggc gattacactg cgcgtctggc actgctggaa gagcagaaat
    32761 cgttgccgtg gcaggcggtc tgggaaatgt attgccaacg tcacgatacg ccagcaggta
    32821 gcgaatggct ggagagcgtg cgggcttatg agaaagaaat tttgagtcgc cgcgggtaaa
    32881 cactgccgga tgcggcgcga gcgccttatc cggcctacgg gtcggcaaca gttgtaggcc
    32941 tgataagacg cgacagcgtc gcatcaggca ttgattgccg gatgcggcac aagtgcctta
    33001 tccggcctac aggtcggcaa tagttgtagg cctgataaga cgcgacagcg tcgcatcagg
    33061 cattgattgc cggatgcggc acaagtgcct tatccggcct acaggtcggc aacagttgta
    33121 ggcctgataa gacgcgacag cgtcgcatca ggcattgatt gccggatgcg gcacaagtgc
    33181 cttatcaggc ctacaggtcg gcaatagttg taggcctgat aagacgcgac agcgtcgcat
    33241 caggcattga ttgccggatg cggcgcgagc gccttatccg gcctacgggt cgtgcatccg
    33301 acaacaccga atttacagga acacagaaca tgcaaaacat tactcagtcc tggtttgtcc
    33361 agggaatgat caaagccacc accgacgcct ggctgaaagg ctgggatgag cgcaacggcg
    33421 gcaacctgac gctacgcctg gatgaagccg atatcgcacc atatcacgac aatttccacc
    33481 aacaaccgcg ctatatcccg ctcagccagc ccatgccttt actggcaaat acaccgttta
    33541 ttgtcaccgg ctcgggcaaa ttcttccgta acgtccagct tgatcctgcg gctaacttag
    33601 gcatcgtaaa agtcgacagc gacggcgcgg gctaccacat tctttggggg ttaaccaacg
    33661 aagccgtccc cacttccgaa cttccggctc acttcctttc ccactgcgag cgcattaaag
    33721 ccaccaacgg caaagatcgg gtgatcatgc actgccacgc caccaacctg atcgccctca
    33781 cctatgtact tgaaaacgac accgcggtct tcactcgcca actgtgggaa ggcagcaccg
    33841 agtgtctggt ggtattcccg gatggcgttg gcattttgcc gtggatggtg cccggcacgg
    33901 acgaaatcgg ccaggcgacc gcacaagaga tgcaaaaaca ttcgctggtg ttgtggccct
    33961 tccacggcgt cttcggcagc ggaccgacgc tggatgaaac cttcggttta atcgacaccg
    34021 cagaaaaatc agcacaagta ttagtgaagg tttattcgat gggcggcatg aaacagacca
    34081 tcagccgtga agagttgata gcgctcggca agcgtttcgg cgttacgcca ctcgccagtg
    34141 cgctggcgct gtaaggagca aacatgatcc gcaaagcctt tgtcatgcag gtaaaccccg
    34201 acgcccacga agagtatcag cgtcggcata atcccatctg gccagaactg gaagcagtgc
    34261 tgaaatctca cggtgcgcat aactacgcca tctatctcga caaagcgcgt aatctgctgt
    34321 ttgccatggt agagattgaa tctgaagaac gctggaatgc ggttgccagt actgatgttt
    34381 gccaacgttg gtggaaatac atgaccgatg ttatgcccgc taacccggat aacagcccgg
    34441 tgagtagcga gctgcaagaa gtgttttacc tgccttaatg agttgcggtg ccggaaaata
    34501 tccagcaccg cgccttcatc agaagaagta tttaaagcga acgcgtgcgc cgtaacggtc
    34561 atcagtatca tcaccgtgtt ttttatcacc gtcgctatcc agaatggagt aatacgtccc
    34621 gaggtaaata ttaaagttct ccatatccat cacattagcg aactgataag acgcatgaat
    34681 ggtgtgaatg gagtacgtcc cttcatcatc aatccagcag tcgttatcac aaactacacc
    34741 gctgaattca tcaatcttat tgtgcgcgta gatataaccg agctcgaaac gtttccacag
    34801 cgcgttaatc ccggcagtga aatctttctc attattagca tctaaatagg cggtattaag
    34861 attaaccaca atgccattgt ccggatccgt tttcaggccg ttccaggtca tgctcatccc
    34921 atagccggta cgatcggact gatcgacaaa attacccttg ctatcggtat aaccataagc
    34981 attatttacc acgttcgctt ccatcgctgc ggaaacggtg aattcttccg tcggcgacca
    35041 ggcaattact gggcgcagat aagcaacatt tttctgctgc tccatatcgc gtccatgata
    35101 attaccgtca ttatataaag atgttccgtc ttcaagtaac gtatttaatt caaaatacca
    35161 gttatcgagt tgtttgctga cgaggaaatt accgccagcg ttagagcgcc cgcggccctc
    35221 tttcatcata tagatataac cgctgccatc gtcataaaga tcgttcgcag tattaccgga
    35281 atgttcaaca aaggtatcct gattcagcgg gaacatatcg taggcttcaa aacggcctac
    35341 tttgaccttc cagtcgtttt ctttaccaaa gaagaatacc gcatcatcga tatttactga
    35401 accgtgcata tcacccagcg gttgtgcgga gaacccggcg aaataaccgt tgtccatctt
    35461 tcgcataccg tcaaaaccta acagaatacg accattgaga ttccactgtt cattagtggg
    35521 atcgctattc acatcagcgt tggtcattgc cagcaggcca tgattacttt ccgcatccat
    35581 attaaattct acgtcgccgt agatttttaa atcgccataa cctgaaagca aaagattagg
    35641 tgaggtggca tttttctttg cagattccgc cgttgcctgt ccatttaccg gcgtattgcc
    35701 ctgagcggcc ttaatttcgc ggatctcagc ggcttgttgt gtctgcagct gtttaacctg
    35761 gctctctgct tttgctgccc gcatttctgc cgcttccagg cgttcttcca gcaatgccat
    35821 gcgttgttcc agcgttaaat gctgtgtttt tgccataccg gtactacatg tcaataataa
    35881 accgatggct aaagataata tcgatttttt cattatttac gttccctgaa ataaaggaga
    35941 ccctacgctt tccaaaagga atacgtatat agagaaatat aaagtgtgca ctttcgaatt
    36001 tttaatccaa cttcagcagg ccgatggata gtatcccgcg gcataatatg agtaaatccg
    36061 ctgatttcct ggaacgtgag gaatataaca atagtgccgt ttttaactaa atatcgtaaa
    36121 aaatattaga tatgattcaa actgactcat aagccacaaa tataaataac gtggcagcaa
    36181 aatatccgcg acaattaaac attcacaaaa tcattaaata atgatttttt attcacaaca
    36241 tttatttaac ccatcaatat gtgccttaca ccgcaaaatt tatccttcac tctgctttat
    36301 attgtcacga cttcacgaca tatccgcgct catcacaaac ccgccccgcc gttacaatta
    36361 actgaaatgt tttttcatgg agtccgataa tggcagctct tactgcaagc tgtattgccc
    36421 tgaatattca gggcaatggc gcttattccg ttctgaagca gttggcgaca atagcgttac
    36481 aaaacggttt tatcaccgac tcacaccagt tcctgcaaac cctgctgctg cgcgaaaaaa
    36541 tgcactctac tggatttggt tccggtgtcg ccgtgccgca cggtaaaagc gcctgcgtta
    36601 aacaaccgtt cgtattattc gcccgcaaag cgcaggctat tgactggaaa gccagcgatg
    36661 gcgaagacgt caattgctgg atctgcctcg gcgtgccgca aagcggcgaa gaggatcagg
    36721 tcaaaatcat cggcacactg tgtcgcaaaa ttatccacca ggattttatt catcaactgc
    36781 aacagggcga taccgaccag gtgcttgcct tgttaaatca aaccctcagc tcataaggaa
    36841 gtggcgatgg agtcatcctt acgtattgtc gcgatcacca actgccccgc cgggatcgct
    36901 cacacctaca tggtggcgga agccctggaa cagaaagccc gttctctcgg ccataccata
    36961 aaagtggaaa ctcaagggtc cagtggcgtt gaaaaccgct tatccagcga agagattgcc
    37021 gctgccgatt acgtcattct cgctaccggg cgtggcctga gcggtgatga tcgcgcgcgg
    37081 tttgccggga agaaagttta tgagattgcc atctcccagg cgttgaaaaa tatcgaccag
    37141 attttcagcg aattaccgac aaactcgcag ctttttgccg cagatagcgg cgtgaagctt
    37201 ggcaaacagg aagtgcaaag cggcagcgtg atgagccacc tgatggcggg cgtctctgcg
    37261 gcgctgccgt ttgtcatcgg cggtggtatc ctggtggcgc ttgccaacat gctggtgcag
    37321 ttcggtttgc cgtataccga tatgtcgaaa ggcgcgccgt cgtttacctg ggtagttgaa
    37381 tccatcggtt accttggctt cacctttatg atccccatca tgggcgctta tattgcctcg
    37441 tcgattgccg ataaaccggc tttcgctccg gcgtttctgg tttgctatct ggcgaacgac
    37501 aaagcgctgc tcggcaccca gtcgggtgcg ggattcctcg gcgcggtggt gctggggctg
    37561 gcgattggct atttcgtctt ctggttccgc aaagtgcgcc ttggcaaagc attacaaccg
    37621 ctgctcggtt caatgctgat cccgttcgtt actctgctgg ttttcggcgt gctcacttac
    37681 tacgttatcg ggccggtaat gtccgacctc atgggcgggc tgctccactt cctgaatacc
    37741 attcctccat caatgaagtt tgcggcagcg tttctggtcg gtgcgatgct ggcgttcgat
    37801 atgggcggcc ccatcaataa aaccgcctgg ttcttctgct tctcactgct ggaaaaacac
    37861 atttatgact ggtacgccat cgtcggcgtt gtcgcgttga tgccgcccgt tgcggcgggt
    37921 cttgcgacgt tcattgcgcc caaactgttt acccgacagg aaaaagaggc tgccagtagt
    37981 gccattgtgg tcggtgccac agtcgcaacc gaaccggcta taccttacgc tctggcagct
    38041 ccgttgccga tgattaccgc caatacgctg gcgggcggca ttaccggcgt gctggtgatc
    38101 gctttcggaa tcaaacgtct ggcacctggt ttgggtatct ttgacccgct gatcggcctg
    38161 atgtcgccgg tagattcgtt ttatctggtg ctggcgattg gcctcgcgct gaacatttca
    38221 ttcattatcg tcctgaaagg attgtggtta cgccgcaaag cgaaagccgc gcaacaggag
    38281 cttgtccatg aacattgagt tactgcaaca gttgtgcgaa gccagcgccg tcagcggcga
    38341 tgaacaggaa gttcgcgaca ttctgataaa cacgctggaa ccttgcgtga atgaaatcac
    38401 cttcgatggt ctgggcagct ttgttgcccg taaggggaat aaaggtccaa aagttgccgt
    38461 tgtcggacat atggatgaag tcggctttat ggtcacccac atcgacgaga gcggttttct
    38521 gcgttttacc accattggcg gctggtggaa tcagtcgatg ctcaaccacc gggtaaccat
    38581 acgcacacac aagggagtga aaatccctgg tgtgattggt tccgtcgcgc ctcatgcgtt
    38641 aacggaaaag caaaagcaac aaccgctgtc atttgatgag atgttcattg atattggcgc
    38701 gaacagtcgc gaagaggtgg aaaagcgcgg cgtggaaatt ggtaatttta ttagcccgga
    38761 agccaatttt gcctgctggg gcgaagataa agtggtcggc aaggcgttgg ataaccgcat
    38821 cggctgcgca atgatggctg aactattgca gacggtgaat aatcccgaaa ttacgctgta
    38881 tggcgttggc agtgtggaag aagaagttgg gctacgcggg gcgcaaacct cggcggaaca
    38941 cattaaaccg gacgtcgtga tcgtgttgga taccgccgta gcgggcgatg ttccgggcat
    39001 tgataacatt aaatacccgc tgaaactggg ccaggggccg gggctgatgc tgtttgacaa
    39061 gcgctacttc cccaaccaga aactggtagc agcgttaaaa agctgtgccg cacataacga
    39121 tttaccgctg caattttcca ccatgaaaac cggtgcgacg gatggcgggc gctacaacgt
    39181 gatgggcggc gggcgtccgg ttgtcgcgct gtgtctgcca actcgttatc tgcacgccaa
    39241 cagcggtatg atttcaaaag ccgattacga agctctgctc acgctgatac ggggttttct
    39301 gacgacctta actgcggaga aagtcaacgc gtttagccag ttccgtcagg tggattaatg
    39361 ctaaacgaac gccagttaaa gattgtcgat ctgctggagc aacagccgcg cacgcctggc
    39421 gagctggcgc aacagactgg cgtttcaggc aggaccatcc tgcgtgatat tgactatctc
    39481 aacttcaccc ttaacggcaa agcccgcatt ttcgccagtg gcagtgcggg ctatcagctg
    39541 gaaatcttcg agcgccgcag cttttttcag ttgctgcaaa agcacgataa cgacgatcgg
    39601 ctgctggcgc tgttattact gaatactttc actccccgtg cgcaactcgc ctcggcgctt
    39661 aatttgccag aaacgtgggt agcagagcgt ctgccccggt taaaacagcg ttatgaacgc
    39721 acttgttgcc tggccagccg ccctggtttg ggccatttca ttgatgagac agaagagaaa
    39781 cgcgttatct tgctggcgaa cttgctgcgc aaagatccgt ttttaattcc gctggcgggc
    39841 ataacacgag acaaccttca gcatttatcc acggcctgcg acaaccaaca ccgctggccg
    39901 ctcatgcagg gtgattatct ctccagcctg attctggcga tttacgccct gcgtaatcaa
    39961 ctgaccgatg agtggccgca atatcccggt gacgagataa aacaaatcgt tgaacaaagc
    40021 ggcatgtttc ttggtgataa cgctgtaaga accctgacag gtttgataga gaaacagcat
    40081 cagcaagcgc agataatttc tgccgataat gtgcagcggt tgctgcaaag ggtgccgggc
    40141 atcgcgtcat tgaatattat tgatacgcgg ctggttgaga acattaccgg gcatttatta
    40201 cgttgccttg ccgcaccagt gtggattgct gagcaccgcc aaagcagcat gaataacctg
    40261 aaagcagcct ggcctgcggc ctttgatatg agtctgcact ttattacgct actgcgtgaa
    40321 cagctcgata ttcccctttt cgacagcgat ctgctcggtt tgtattttgc ctgtgcgctg
    40381 gagcggcatc aaaacgaacg ccagccgatc attttgctct cggaccagaa cgcgattgcc
    40441 accattaatc agctcgccat tgagcgcgat gttttaaatt gtcgggtgat tattgcccgt
    40501 agcttaagcg agcttgttgc cattcgcgaa gagattgagc cgttattgat cattaacaac
    40561 agccattatt tactggatga cgcggtaaat aattacatca ccgtaaaaaa tatcattacg
    40621 gctgccggta tcgaacaaat aaaacatttt ctggcgacgg catttattcg ccagcaaccg
    40681 gagcgttttt tctctgcccc cggaagtttt cattattcga atgtacgcgg tgaaagctgg
    40741 caacatatta cccggcaaat ttgtgcgcaa ttagtcgcac aacaccatat taccgccgat
    40801 gaagcacaac gcatcatcgc ccgcgaaggc gaaggtgaaa acctgattgt taatcgcctc
    40861 gccatcccac attgctggag cgaacaggag cgacgttttc gtggattttt tattaccctc
    40921 gcccaaccag ttgaggtgaa taacgaagtc attaaccatg tcttgatcgc ctgcgccgcc
    40981 gccgatgcgc gtcatgagct aaaaatattt agctatctgg caagcatatt gtgtcagcat
    41041 ccggcggaga ttattgccgg gttaacagga tatgaggcat ttatggagtt acttcacaag
    41101 gggtgaactg tgtcggatgc gccgcatccg acactgcatt tatcatcaaa aacgtttaac
    41161 gcaggctatt atagtcatca accatttcgt tgtactcgcg taatgctctc gggaaagagt
    41221 cttcgaccat ccagcttgag tttgcgtcct gaagttgctc tttatcccag tcagagtacg
    41281 ggactttatc tctgatgcgg cgaacgtatt ttttagcctc gagttgatac tggcctgccg
    41341 aattaataaa cgagaaattc atgccgcctt tatccgcttc tttggcctgc gccactagcg
    41401 tttccagttc agacactttc ttcattgccg cttctgcatc aaacttatct tgcgatatca
    41461 ggttattaat ttgtttcgct gaaatcatga ctgccagaga gtagtagtgg aatgttttcc
    41521 cttctctttc ttcaatattt ttcagttccg caagctgacg cttatcatta atttcctgaa
    41581 tcgccgcatg ataagattcg gctacaggtt caaaggcttc cagatttttt aagaatgtct
    41641 ggtgcagcgt tttccctttc gcaaacgcat cgtctttata attttcctgg gtgtaatatt
    41701 tatccatttc gttaatggta ttacccaacg ccacggcagc atcgatataa ctcaccgcca
    41761 cgccatcaat tggttgcagc gcaggcgtta acgccacagc actttttacg cctttttcac
    41821 actcagcgag gttggattca ctaatgccgt agatgccata aacagtacgc tcttcaccgg
    41881 taggcccctg tttaaaatct ttcagccagt cagcataacg cgccagactg cgctgtaccg
    41941 ggatctgtaa cttgttgtag cacttgatat agacatccat tttttcgtcg aaaaccgctt
    42001 gttcatcgac caccggttgc gcaggtgttt caggtttagc ttctgctttt gcaacgggag
    42061 cttcagtagg tttcgcttca ggagctggtg cggcaggttg actattggca ggcgggagcg
    42121 tttctgtttc ggctttttta tcatcacaac ccgtcagacc gagggacatg atggcgacta
    42181 taatagcgga agataataaa t
//
LOCUS       DAPGUL010000029        41943 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.029, whole genome shotgun sequence.
ACCESSION   DAPGUL010000029 DAPGUL010000000
VERSION     DAPGUL010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 41943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41943
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.029"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..1114
                     /locus_tag="RHX21_001718"
     CDS             <1..1114
                     /locus_tag="RHX21_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001736301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDV1986918.1"
                     /translation="IFPNLEKAQAIFTPVMNGSVNIMSIMIAFLVARNMAISYEQDDL
                     LCGLTAIGAFFIVYTPYQMIDGQAFLTTKYLGAQGLFVAVIVALITSEIFCRLARNPK
                     ITITMPAAVPPAVARSFKVLLPIFFVMVFFSALNYCLTLISPAGLNDLIYTLIQTPLK
                     HMGTNIFAVIILGAVGNFLWVLGIHGPNTTSAIRETVFSEANLENLSWAAQHGTTWGA
                     PYPITWTSINDAFANCGGSGMTLGLLLAIFIASKRAEYRDLAKMSFIPGIFNINEPIM
                     FGLPIVLNPIMMVPFIMVPIVNCAIGYFFVSMEIIPPVAYAVPWTTPGPLIAFLGTGG
                     NWLALLVGFLCLGVATMIYLPFVIAANKVNNMTTNG"
     gene            1142..1453
                     /locus_tag="RHX21_001719"
     CDS             1142..1453
                     /locus_tag="RHX21_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001314746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDV1986919.1"
                     /translation="MFADEELVMELLVNAGQARSDAMEAIRCAGQKDWQGATQLMASS
                     ESACLQAHKIQTALISQDEGCGKIKVNLILIHAQDHLMNAILCQDLAREIISLRKELH
                     A"
     gene            1509..3182
                     /locus_tag="RHX21_001720"
     CDS             1509..3182
                     /locus_tag="RHX21_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate porin"
                     /protein_id="HDV1986920.1"
                     /translation="MNIKTLNVSLLSFSIITALFPLNAMATKLTIEQRLELLENELSQ
                     NKQELKATQNELGVYKSRLSTLQKSITENKYKSASLAEISATSPVADNIKNENGEQNS
                     SAAAHTINGSQQVAVIESKGDKTTIESVTLKDISKYIKDDIGFSYQGYFRSGWGTGNH
                     GSPQTYAAGSLGRFGNEMSGWFDLTLNQRVYNQDGKTANAVVTYDGNVGEQYNDAWFG
                     DSANENIMQFSDIYLTTRGFLPFAPEADFWVGKHKLPQYEIQMLDWKTLTTDVAAGVG
                     IENWALGVGLFDMSLSRDDVDVYSRDFSRTSQMNTNSVDVRYRNIPLWDDATLSLMAK
                     YSAPNKTDQQQDNENDNSYFEMKDSWMLTSVLRQNLQRDTFNEFTLQVANNSYASSFA
                     SFSDASNTMAHDRYYYGDHTNGIAWRLISQGEMYLTDNIIMANALVYSHGEDVYSYES
                     GAHSDFDSIRTVIRPAWIWNTWNQTGLELGWFKQQNKTQQGVTLNESAYKTTLWHALK
                     VGESILGSRPEIRFYGTYINILDNELSNFKFNENSKDEFMAGIQAEVWW"
     gene            3207..4646
                     /locus_tag="RHX21_001721"
     CDS             3207..4646
                     /locus_tag="RHX21_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000012594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDV1986921.1"
                     /translation="MSGFKKGFLWGGAVAAHQLEGGWNEGGKGISIADVMTAGAHGVP
                     REVTEGVIDGLNYPNHEAIDFYHRYKTDIQLFAEMGFKCFRTSIAWTRIFPQGDEQEP
                     NEEGLQFYDDLFDECLKQGMEPVVTLSHFEMPYHLVTKYGGWRNRKLIDFFIRFASTV
                     FTRYKEKVKYWMTFNEINNQVNFSESLCPFTNSGILYSPEEDINEREQIMYQAVHYEL
                     VASALAVQTGKSINPEFNIGCMIAMCPIYPLTCAPNDMMMATKAMHRRYWFTDVHARG
                     YYAQHMLNYFARKGFNLDITPEDNAILASGCVDFIGFSYYMSFTTQFSPDNPQLDYVE
                     PRDLVSNPYIDTSEWGWQIDPAGLRYSLNWFWDHFQLPLFIVENGFGAVDQRQADGTV
                     NDHYRIDYFASHIREMKKAVVEDGVDLIGYTPWGCIDLVSAGTGEMKKRYGMIYVDKD
                     NEGKGTLERIRKASFYWYRDLIANNGENI"
     gene            complement(4703..4921)
                     /gene="marB"
                     /locus_tag="RHX21_001722"
     CDS             complement(4703..4921)
                     /gene="marB"
                     /locus_tag="RHX21_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple antibiotic resistance protein MarB"
                     /protein_id="HDV1986922.1"
                     /translation="MKPLSSAIAAALILFSAQGVAEQTTQPVVTSCANVVVVPPSQEQ
                     PPFDLNHMGTGSDKSDALGVPYYNQHAM"
     gene            complement(4953..5336)
                     /gene="marA"
                     /locus_tag="RHX21_001723"
     CDS             complement(4953..5336)
                     /gene="marA"
                     /locus_tag="RHX21_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707445.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MDR efflux pump AcrAB transcriptional activator
                     MarA"
                     /protein_id="HDV1986923.1"
                     /translation="MSRRNTDAITIHSILDWIEDNLESPLSLEKVSERSGYSKWHLQR
                     MFKKETGHSLGQYIRSRKMTEIAQKLKESNEPILYLAERYGFESQQTLTRTFKNYFDV
                     PPHKYRMTNMQGESRFLHPLNHYNS"
     gene            complement(5356..5790)
                     /gene="marR"
                     /locus_tag="RHX21_001724"
     CDS             complement(5356..5790)
                     /gene="marR"
                     /locus_tag="RHX21_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310164.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple antibiotic resistance transcriptional
                     regulator MarR"
                     /protein_id="HDV1986924.1"
                     /translation="MKSTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFK
                     VLCSIRCAACITPVELKKVLSVDLGALTRMLDRLVCKGWVERLPNPNDKRGVLVKLTT
                     SGAAICEQCHQLVGQDLHQELTKNLTADEVATLEHLLKKVLP"
     gene            6002..6667
                     /gene="marC"
                     /locus_tag="RHX21_001725"
     CDS             6002..6667
                     /gene="marC"
                     /locus_tag="RHX21_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter MarC"
                     /protein_id="HDV1986925.1"
                     /translation="MLDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQS
                     LMASVYVFAIMMVAYYAGQLVMDTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAIDSP
                     EAKSKSEELEDEPSANIAFVPLAMPSTAGPGTIAMIISSASTVRQSSTFADWVLMVAP
                     PLIFFLVAVILWGSLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGILEIIK
                     TYH"
     gene            complement(6692..7882)
                     /gene="ydeA"
                     /locus_tag="RHX21_001726"
     CDS             complement(6692..7882)
                     /gene="ydeA"
                     /locus_tag="RHX21_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose MFS transporter"
                     /protein_id="HDV1986926.1"
                     /translation="MTTNTVSRKVAWLRVVTLAVAAFIFNTTEFVPVGLLSDIAQSFH
                     MQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLSFLSWSFT
                     VLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGLPLGRIV
                     GQYFGWRMTFFAIGIAALITLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSIYLLT
                     VVVVTAHYTAYSYIEPFVQNIAGFSANFATALLLLLGGAGIIGSVIFGKLGNQYASAL
                     VSTAIALLLVCLALLLPAANSEIHLGVLSIFWGIAMMIIGLGMQVKVLALAPDATDVA
                     MALFSGIFNIGIGAGALVGNQVSLHWSMSMIGYVGAVPAFAALIWSIIIFRRWPVTLE
                     EQTQ"
     gene            complement(8032..9145)
                     /gene="yneK"
                     /locus_tag="RHX21_001727"
                     /pseudo
     CDS             complement(8032..9145)
                     /gene="yneK"
                     /locus_tag="RHX21_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416044.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="putative protein YneK"
     gene            complement(9223..10104)
                     /locus_tag="RHX21_001728"
     CDS             complement(9223..10104)
                     /locus_tag="RHX21_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV1986927.1"
                     /translation="MDLTQLEMFNAVAEAGSITQAAAKVHRVPSNLTTRLRQLETELG
                     VDLFIRENQRLRLSPAGHNFLRYSQQILALVDEARSVVAGDEPQGLFSLGSLESTAAV
                     RIPATLAEFNHRYPKIQFSLSTGPSGTMLEGVLEGKLNAAFIDGPINHTAIDGIPVYR
                     EELMIVTPQGHAPVIRASQVNGSNIYAFRANCSYRRHFESWFHADGAAPGTIHEMESY
                     HGMLACVVAGAGIALIPRSMLESMPGHHQVEAWPLAEQWRWLTTWLVWRRGAKTRPLE
                     AFIQLLDVPDSAKQGYQ"
     gene            10205..11593
                     /gene="sad"
                     /locus_tag="RHX21_001729"
     CDS             10205..11593
                     /gene="sad"
                     /locus_tag="RHX21_001729"
                     /EC_number="1.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate-semialdehyde dehydrogenase"
                     /protein_id="HDV1986928.1"
                     /translation="MTITPATHAISINPATGEQLSVLPWAGANDIENALQLAAAGFRD
                     WRETNIDYRAEKLRDIGKALRARSEEMAQMITREMGKPINQARAEVAKSANLCDWYAE
                     HGPAMLKAEPTLVENQQAVIEYRPLGTILAIMPWNFPLWQVMRGAVPIILAGNGYLLK
                     HAPNVMGCAQLIAQVFKDAGIPQGVYGWLNADNDGVSQMIKDSRIAAVTVTGSVRAGA
                     AIGAQAGAALKKCVLELGGSDPFIVLNDADLELAVKAAVAGRYQNTGQVCAAAKRFII
                     EEGIASAFTERFVAAAAALKMGDPRDEENALGPMARFDLRDELHHQVEKTLAQGARLL
                     LGGEKMAGAGNYYPPTVLANVTPEMTAFREEMFGPVAAITVAKDAEHALELANDSEFG
                     LSATIFTTDETQARQMAARLECGGVFINGYCASDARVAFGGVKKSGFGRELSHFGLHE
                     FCNIQTVWKDRI"
     gene            11657..12583
                     /gene="glsB"
                     /locus_tag="RHX21_001730"
     CDS             11657..12583
                     /gene="glsB"
                     /locus_tag="RHX21_001730"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase B"
                     /protein_id="HDV1986929.1"
                     /translation="MAVAMDNAILENILRQVRPLIGQGKVADYIPALATVDGSRLGIA
                     ICTVDGQLFQAGDAQERFSIQSISKVLSLVVAMRHYSEEEIWQRVGKDPSGSPFNSLV
                     QLEMEQGIPRNPFINAGALVVCDMLQGRLSAPRQRMLEVVRGLSGVSDISYDTVVARS
                     EFEHSARNAAIAWLMKSFGNFHHDVTTVLQNYFHYCALKMSCVELARTFVFLANQGKA
                     IHIDEPVVTPMQARQINALMATSGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPHEMAI
                     AVWSPELDDAGNSLAGIAVLEQLTKQLGRSVY"
     gene            12583..12942
                     /locus_tag="RHX21_001731"
     CDS             12583..12942
                     /locus_tag="RHX21_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4186 domain-containing protein"
                     /protein_id="HDV1986930.1"
                     /translation="MQSLDPLFARLSRSKFRSRFRLGMKERQYCLEKGAPVIEQHAAD
                     FVAKRLAPALPANDGKQTPMRGHPVFIAQHATATCCRGCLAKWHNIPQGVSLSEEQQR
                     YIVAVIYHWLVVQMNQP"
     gene            13081..14499
                     /locus_tag="RHX21_001732"
     CDS             13081..14499
                     /locus_tag="RHX21_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310156.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDV1986931.1"
                     /translation="MHVHPISTFRLFQEGHLLRNSIAIFALTTLFYFIGAELRLVHEL
                     SLFWPLNGVMAGVFARYVWLNRLHYYAISYVAMLVYDAITTEWGLVSLVINFSNMMFI
                     VTVALLVVRDKRLGKNKYEPVSALRLFNYCLIAALLCAIVGAIGSVSIDSLDFWPLLA
                     DWFSEQFSTGVLIVPCMLTLAIPGVLPRFKAEQMMPAIALIVSVIASVVIGGAGSLAF
                     PLPALIWCAVRYTPQVTCLLTFVTGAVEIVLVANSVIDISVGSPFSIPEMFSARLGIA
                     TMAICPIMVSFSVAAINSLMKQVALRADFDFLTQVYSRSGLYEALKSPSLKQTQHLTV
                     MLLDIDYFKSINDNYGHECGDKVLSVFARHIQKIVGDKGLVARMGGEEFAVAVPSVNP
                     VDGLLMAEKIRKGVELQPFTWQQKTLYLTVSIGVGSGRASYRTLTDDFNKLMVEADTC
                     LYRSKKDGRNRTSTMRYGEEVV"
     gene            14726..16177
                     /gene="uxaB"
                     /locus_tag="RHX21_001733"
     CDS             14726..16177
                     /gene="uxaB"
                     /locus_tag="RHX21_001733"
                     /EC_number="1.1.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HDV1986932.1"
                     /translation="MKTLNRRDFPGAQYPERIIQFGEGNFLRAFVDWQIDLLNEHTDL
                     NSGVVVVRPIETSFPPSLSTQDGLYTTIIRGLNEKGEAVSDARLIRSVNREISVYSEY
                     DEFLKLAHNPEMRFVFSNTTEAGISYHAGDKFDDAPAVSYPAKLTRLLFERFSHFNGA
                     LDKGWIIIPCELIDYNGDALRELVLRYAQEWALPEAFIQWLDQANSFCSTLVDRIVTG
                     YPRDEVAKLEEELGYHDGFLDTAEHFYLFVIQGPKSLATELRLDKYPLNVLIVDDIKP
                     YKERKVAILNGAHTALVPVAFQAGLDTVGEAMNDAEICAFVEKAIYEEIIPVLDLPRD
                     ELESFASAVTGRFRNPYIKHQLLSIALNGMTKFRTRILPQLLAGQKAKGTLPARLTFA
                     LAALIAFYRGERNGETYPVQDDAHWLERYQQLWSQHRDRVIGTQELVAIVLAEKDHWE
                     QDLTQVPGLVEQVANDLDAILEKGMREAVRPLC"
     gene            16384..17298
                     /locus_tag="RHX21_001734"
     CDS             16384..17298
                     /locus_tag="RHX21_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416037.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bestrophin family protein"
                     /protein_id="HDV1986933.1"
                     /translation="MIVRPQQHWLRRIFVWHGSVLSKISSRLLLNFLFSIAVIFMLPW
                     YTHLGIKFTLAPFSILGVAIAIFLGFRNNAGYARYVEARKLWGQLMIASRSLLREVKT
                     TLPDSASVREFARLQIAFAHCLRMTLRKQPQAEVLAHYLKTEDLQPVLASNSPANRIL
                     LIMGEWLAVQRRNGQLSDILFISLNDRLNDISAVLAGCERIAYTPIPFAYTLILHRTV
                     YLFCIMLPFALVVDLHYMTPFISVLISYTFISLDCLAEELEDPFGTENNDLPLDAICN
                     AIEIDLLQMNDEAEIPAKILPDRHYQLT"
     gene            complement(17302..18060)
                     /gene="tam"
                     /locus_tag="RHX21_001735"
     CDS             complement(17302..18060)
                     /gene="tam"
                     /locus_tag="RHX21_001735"
                     /EC_number="2.1.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trans-aconitate 2-methyltransferase"
                     /protein_id="HDV1986934.1"
                     /translation="MSDWNPSLYLHFAAERSRPAVELLARVPLENIEYVADLGCGPGN
                     STALLNQRWPAARITGIDSSPAMIAEARSALPDCQFVEADIRNWQPVQALDLIFANAS
                     LQWLPDHYELFPHLVSLLNPQGVLAVQMPDNWLEPTHVLMREVAWEQNYPDRGREPLA
                     GVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQLFL
                     KRYHQMLEEQYPLQENGQILLAFPRLFIVARRME"
     gene            complement(18117..18407)
                     /gene="lsrG"
                     /locus_tag="RHX21_001736"
     CDS             complement(18117..18407)
                     /gene="lsrG"
                     /locus_tag="RHX21_001736"
                     /EC_number="5.3.1.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione
                     isomerase"
                     /protein_id="HDV1986935.1"
                     /translation="MHVTLVEINVHEDKIDEFIEVFRQNHLGSVQEEGNLRFDVLQDP
                     EVNSRFYIYEAYKDEDAVAFHKTTPHYKTCVAKLESLMTGPRKKRLFNGLMP"
     gene            complement(18431..19306)
                     /gene="lsrF"
                     /locus_tag="RHX21_001737"
     CDS             complement(18431..19306)
                     /gene="lsrF"
                     /locus_tag="RHX21_001737"
                     /EC_number="2.3.1.245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxy-5-phosphonooxypentane-2,4-dione
                     thiolase"
                     /protein_id="HDV1986936.1"
                     /translation="MADLDDIKDGKDFRTDQPQQNIPFILKGCGALDWGMQSRLSRIF
                     NPKTGKTVMLAFDHGYFQGPTTGLERIDINIAPLFEHADVLMCTRGILRSVVPPATNK
                     PVVLRASGANSILAELSNEAVALSMDDAVRLNSCAVAAQVYIGSEYEHQSIKNIIQLV
                     DAGMKVGMPTMAVTGVGKDMVRDQRYFSLATRIAAEMGAQIIKTYYVEKGFERIVAGC
                     PVPIVIAGGKKLPEREALEMCWQAIDQGASGVDMGRNIFQSDHPVAMMKAVQAVVHHN
                     ETADRAYELYLSEKQ"
     gene            complement(19333..20355)
                     /gene="lsrB"
                     /locus_tag="RHX21_001738"
     CDS             complement(19333..20355)
                     /gene="lsrB"
                     /locus_tag="RHX21_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter substrate-binding
                     protein LsrB"
                     /protein_id="HDV1986937.1"
                     /translation="MTLHRFKKIALLSALGIAAISMNVQAAERIAFIPKLVGVGFFTS
                     GGNGAQQAGKELSVDVTYDGPTEPSVSGQVQLINNFVNQGYNAIIVSAVSPDGLCPAL
                     KRAMQRGVRVLTWDSDTKPECRSYYINQGTPAQLGGMLVDMAARQVNKDKAKVAFFYS
                     SPTVTDQNQWVKEAKAKIAKEHPGWEIVTTQFGYNDATKSLQTAEGILKAYSDLDAII
                     APDANALPAAAQAAENLKNDKVAIVGFSTPNVMRPYVERGTVKEFGLWDVVQQGKISV
                     YVADALLKKGSMKTGDKLDIQGVGQVEVSPNSVQGYDYEADGNGIVLLPERVIFNKEN
                     IGKYDF"
     gene            complement(20367..21359)
                     /gene="lsrD"
                     /locus_tag="RHX21_001739"
     CDS             complement(20367..21359)
                     /gene="lsrD"
                     /locus_tag="RHX21_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter permease LsrD"
                     /protein_id="HDV1986938.1"
                     /translation="MRIRYGWELALAALLVIEIVAFGAINPRMLDLNMLLFSTSDFIC
                     IGIVALPLTMVIVSGGIDISFGSTIGLCAIALGVLFQSGVPMPLAILLTLLLGALCGL
                     INAGLIIYTKVNPLVITLGTLYLFAGSALLLSGMAGATGYEGIGGFPMAFTDFANLDV
                     LGLPVPLIIFLICLLVFWLWLHKTHAGRNVFLIGQSPRVALYSAIPVNRTLCALYAMT
                     GLASAVAAVLLVSYFGSARSDLGASFLMPAITAVVLGGANIYGGSGSIIGTAIAVLLV
                     GYLQQGLQMAGVPNQVSSALSGALLIVVVVGRSVSLHRQQIKEWLARRANNPLP"
     gene            complement(21359..22387)
                     /gene="lsrC"
                     /locus_tag="RHX21_001740"
     CDS             complement(21359..22387)
                     /gene="lsrC"
                     /locus_tag="RHX21_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter permease LsrC"
                     /protein_id="HDV1986939.1"
                     /translation="MLKFIQNNREITALLAVVLLFVFPGFLDRQYLSVQTLTMVYSSA
                     QILILLAMGATLVMLTRNIDVSVGSITGMCAVLLGMLLNAGYSLPVACVATLLLGLLA
                     GFFNGVLVAWLKIPAIVATLGTLGLYRGIMLLWTGGKWIEGLPAELKELSAPLLFGVS
                     AIGWLTIILVAFMAWLLAKTAFGRSFYATGDNLQGARQLGVRTEAIRIVAFSLNGCMA
                     ALAGIVFASQIGFIPNQTGTGLEMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQID
                     SVLVLLRIPAWWNDFIAGLVLLAVLVFDGRLRCALERNLRRQKYARFMTPPPSVKPAS
                     SGKNREAA"
     gene            complement(22381..23916)
                     /gene="lsrA"
                     /locus_tag="RHX21_001741"
     CDS             complement(22381..23916)
                     /gene="lsrA"
                     /locus_tag="RHX21_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter ATP-binding
                     protein LsrA"
                     /protein_id="HDV1986940.1"
                     /translation="MQTSDTRALPLLCARSVYKQYSGVNVLKGIDFTLHQGEVHALLG
                     GNGAGKSTLMKIIAGITPADSGTLEIGGNNYARLTPVHAHQLGIYLVPQEPLLFPSLS
                     IKENILFGMAKKQLSMQKMKNLLAALGCQFDLHSLAGSLDVADRQMVEILRGLMRDSR
                     ILILDEPTASLTPAETERLFSRLQELLATGVGIVFISHKLPEIRQIADRISVMRDGTI
                     ALSGKTSELSTDDIIQAITPAVREKSLSASQKLWLELPGNRPQHAAGTPVLTLENLTG
                     EGFRNVSLTLNAGEILGLAGLVGAGRTELAETLYGLRTLRGGRIMLNGKEINKLSTGE
                     RLLRGLVYLPEDRQSSGLNLDASLAWNVCALTHNLRGFWAKTAKDNATLERYRRALNI
                     KFNQPEQAARTLSGGNQQKILIAKCLEASPQVLIVDEPTRGVDVSARNDIYQLLRSIA
                     AQNVAVLLISSDLEEIELMADRVYVMHQGEITHSALTGRDINVETIMRVAFGDSQRQE
                     ASC"
     gene            24165..25118
                     /gene="lsrR"
                     /locus_tag="RHX21_001742"
     CDS             24165..25118
                     /gene="lsrR"
                     /locus_tag="RHX21_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LsrR"
                     /protein_id="HDV1986941.1"
                     /translation="MTINDSAISEQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTR
                     LKVSRLLEKGHQSGIIRVQINSRFEGCLEYETQLRRQFSLQHVRVIPGLADADVGGRL
                     GIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGI
                     GQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDD
                     ATIIRSGYISQGEQLMIGRKGAVGDILGYFFDAKGDVVTDIKIHNELIGLPLSSLKTI
                     PVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS"
     gene            25197..26789
                     /gene="lsrK"
                     /locus_tag="RHX21_001743"
     CDS             25197..26789
                     /gene="lsrK"
                     /locus_tag="RHX21_001743"
                     /EC_number="2.7.1.189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416028.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer-2 kinase"
                     /protein_id="HDV1986942.1"
                     /translation="MARLFTPSESKYYLMALDAGTGSIRAVIFDLEGNQIAVGQAEWR
                     HLAVPDVPGSMEFDLNKNWQLACECMRQALHNAGIAPEYIAAVSACSMREGIVLYNNE
                     GAPIWACANVDARAAREVSELKELHNNTFENEVYRATGQTLALSAIPRLLWLAHHRSD
                     IYRQASTITMISDWLAYMLSGELAVDPSNAGTTGLLDLTTRDWKPALLDMAGLRADIL
                     SPVKETGTLLGVVSSQAAELCGLKAGTPVVVGGGDVQLGCLGLGVVRPAQTAVLGGTF
                     WQQVVNLAAPVTDPEMNVRVNPHVIPGMVQAESISFFTGLTMRWFRDAFCAEEKLIAE
                     RLGIDTYTLLEEMASRVPPGSWGVMPIFSDRMRFKTWYHAAPSFINLSIDPDKCNKAT
                     LFRALEENAAIVSACNLQQIADFSNIHPSSLVFAGGGSKGKLWSQILADVSGLPVNIP
                     VVKEATALGCAIAAGVGAGIFSSMAETGERLVRWERTHTPDPEKHELYQDSRDKWQAV
                     YQDQLGLVDHGLTTSLWKAPGL"
     gene            27320..32740
                     /locus_tag="RHX21_001744"
     CDS             27320..32740
                     /locus_tag="RHX21_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter barrel domain-containing
                     lipoprotein"
                     /protein_id="HDV1986943.1"
                     /translation="MNRIYRVIWNCTLQVFQACSELTRRAGKTSTVNLRKSSGLTTKF
                     SRLTLGVLLALSGSASGASLEVDNDQITNIDTDVAYDAYLVGWYGTGVLNILAGGNAS
                     LTTITTSVIGANEDSEGTVNVLGGTWRLYDSGNNARPLNVGQSGTGTLNIKQKGHVDG
                     GYLRLGSSTGGVGTVNVEGEDSVLTTELFEIGSYGTGSLNITDKGYVTSSIVAILGYQ
                     AGSNGQVVVEKGGEWLIKNNDSSIEFQIGNQGTGEATIREGGLITAENTIIGGNATGI
                     GTLNVQDQDSVITVRRLYNGYFGNGTLNISNNGLINNKEYSLVGVQDGSHGVVNVTDK
                     GHWNFLGTGEAFRYIYIGDAGDGELNVSREGKVDSGIITAGMKETGTGNITVKDKNSV
                     ITNLGTNLGYDGHGEMDISNEGLVVSNGGSSLGYGETGVGNVSITTGGMWEVNKNVYT
                     TIGVAGVGNLNISDGGKFVSQNITFLGDKASGIGTLNLMDATSSFDTVGINVGNFGSG
                     IVNVSNGATLNSTGYGFIGGNASGKGIVNISTDSLWNLKTSSTNAQLLQVGVLGKGEL
                     NITTGGIVKARDTQIALNDKSKGDVRVDGQNSLLETFNMYVGTSGTGTLTLTNSGTLN
                     VEGGEVYLGVFEPAVGTLNIGAAHGEAAADAGYITNATKVEFGSGEGVFVFNHTNNSD
                     AGYQVDMLITGDDKDGKVIHDAGHTVFNAGNTYSGKTLVNDGLLTIASHTADGVTGMG
                     SSEVTIASPGTLDILASTNSAGDYTLTNALKGDGLMRVQLSSYDKMFGFTHATGTEFA
                     GVAQLKDSTFTLERDNTAALTHAMLQSDSENTTSVKVGEQSIGGLAMNGGTLIFDTDI
                     PAATLAEGYISVDTLVVGAGDYTWKGRNYQVNGTGDVLIDVPKPWNDPMANNPLTTLN
                     LLEHDDSHVGVQLVKAQTVIGSGGSLTLRDLQGDEVEADKTLHIAQNGTVVAEGDYGF
                     RLTTAPGDGLYVNYGLKALNIHGGQKLTLAEHGGAYGATADMSAKIGGEGDLAINTVR
                     QVSLSNGQNDYQGATYVQMGTLRTDADGALGNTRELNISNAAIVDLNGSTQTVETFTG
                     QMGSTVLFKEGALTVNKGGISQGELTGGGNLNVTGGTLAIEGLNARYNALTSISPNAE
                     VSLDNTQGLGRGNIANDGLLTLKNVTGELRNSISGKGIVSATARTDVELDGDNSRFVG
                     QFNIDTGSALSVNEQKNLGDASVINNGLLTISTERSWAMTHSISGSGDMTKLGTGILT
                     LNNDSAAYQGTTDIVGGEIAFGSDSAINMASQHINIHNSGVMSGNVTTAGDVNVMPGG
                     TLRVAKTTIGGNLENGGTVQMNSEGGKPGNVLTVNGNYTGNNGLMTFNATLGGDNSPT
                     DKMNVKGDTQGNTRVRVDNIGGVGAQTVNGIELIEVGGNSAGNFALTTGTVEAGAYVY
                     TLAKGKGNDEKNWYLTSKWDGVTPADTPDPINNPPVVDPEGPSVYRPEAGSYISNIAA
                     ANSLFSHRLHDRLGEPQYIDSLHSQGSASSMWMRHVGGHERSRAGDGQLNTQANRYVL
                     QLGGDLAQWSSNAQDRWHLGVMAGYANQHSNTQSNRVGYKSDGRISGYSAGLYATWYQ
                     NDANKTGAYVDSWALYNWFDNSVSSDNRSADDYDSRGVTASVEGGYTFEAGTFSGSEG
                     TLNTWYVQPQAQITWMGVKDSDHTRKDGTRIETEGDGNVQTRLGVKTYLNSHHQRDDG
                     KQREFQPYIEANWINNSKVYAVKMNGQTVGHEGARNLGEVRTGVEAKVNNNLSLWGNV
                     GVQLGDKGYSDTQGMLGVKYSW"
     gene            32949..33215
                     /gene="hipB"
                     /locus_tag="RHX21_001745"
     CDS             32949..33215
                     /gene="hipB"
                     /locus_tag="RHX21_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin HipB"
                     /protein_id="HDV1986944.1"
                     /translation="MMSFQKIYSPTQLANAMKLVRQQNGWTQSELAKKIGIKQATISN
                     FENNPDNTTLTTFFKILQSLELSMTLCDTKNASPESTEQQDLEW"
     gene            33215..34537
                     /gene="hipA"
                     /locus_tag="RHX21_001746"
     CDS             33215..34537
                     /gene="hipA"
                     /locus_tag="RHX21_001746"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system serine/threonine
                     protein kinase toxin HipA"
                     /protein_id="HDV1986945.1"
                     /translation="MPKLVTWMNNQRVGELTKLANGAHTFKYAPEWLASRYARPLSLS
                     LPLQRGNITSDAVFNFFDNLLPDSPIVRDRIVKRYHAKSRQPFDLLSEIGRDSVGAVT
                     LLPENETITRPIMAWEKLTEARLEEVLTAYKADIPLGMIREENDFRISVAGAQEKTAL
                     LRIGNDWCIPKGITPTTHIIKLPIGEIRQPNATLDLSQSVDNEYYCLLLAKELGLNVP
                     DAEIIKAGNVRALAVERFDRRWNAERTVLLRLPQEDMCQTFGLPSSVKYESDGGPGIA
                     RIMAFLMGSSEALKDRYDFMKFQVFQWLIGATDGHAKNFSVFIQAGGSYRLTPFYDII
                     SAFPVLGGTGIHISDLKLAMGLNASKGKKTAIDKIYPRHFLATAKVLRFPEVQMHEIL
                     SDFARMIPAALDNVKTSLPTDFPENVVTAVETNVLRLHGRLSREYGSK"
     gene            34849..35057
                     /locus_tag="RHX21_001747"
                     /pseudo
     CDS             34849..35057
                     /locus_tag="RHX21_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226947.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            35491..36054
                     /gene="fimA"
                     /locus_tag="RHX21_001748"
     CDS             35491..36054
                     /gene="fimA"
                     /locus_tag="RHX21_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial major subunit FimA"
                     /protein_id="HDV1986946.1"
                     /translation="MKLKHVGMIVVSVLAMSSAAVSAAEGDESVTTTVNGGVIHFKGE
                     VVNAACAIDSESMNQTVELGQVRSSRLAKAGDLSSAVGFNIKLNDCDTNVSSNAAVAF
                     LGTTVTRNDDTLALQSSAAGSAQNVGIQILDRTGEVLILDGATFSAKTDLIDGTNILP
                     FQARYIALGQSVAGTANADATFKVQYL"
     gene            36415..37125
                     /locus_tag="RHX21_001749"
     CDS             36415..37125
                     /locus_tag="RHX21_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HDV1986947.1"
                     /translation="MQTTRTPYSISFMATVLLLLLFACHSTVANAAVALGATRVIYPA
                     NQKQVLLPVTNNDPASVYLIQSWIENAGDQKDTQFVITPPLFSMQGKKENTLRIINAT
                     NHQLPGDRESLFWVNVKAIPAMEKDQKNENTLQLAIISRIKMFYRPTNLAMAPEEAPA
                     MLRFRRSGSKLTLINPTPYFITVTNMKAGNSNLPNTMVPPKGEVSVDITHAATGDISF
                     QTINDYGALTPRIKATMQ"
     gene            37167..39818
                     /locus_tag="RHX21_001750"
     CDS             37167..39818
                     /locus_tag="RHX21_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310137.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDV1986948.1"
                     /translation="MTAIRAAFKAYRMHQVLIMPRFARLTIALGLATAVFPVDAEYYF
                     NPRFLSNDLAESVDLSAFTKGREAPPGTYRVDIYLNDEFMTSRDITFIADDNNAELIP
                     CLSTDLLVSLGIKKSALLDNKEHSAEKHVPDNSACTPLQDRLADASTEFDVGQQHLSL
                     SVPQIYVGRMARGYVSPDLWEEGINAGLLNYSFNGNSINNRSNHNAGKSNYAYLNLQS
                     GINIGSWRLRDNSTWSYYSGSSNSSDSNKWQHINTSAERDIIPLRSRLTVGDSYTDGD
                     IFDSVNFRGLKINSTEAMLPDSQHGFAPVIHGIARGTAQVSVKQNGYDVYQTTVPPGP
                     FTIDDINSAANGGDLQVTIKEADGSIQTLYVPYSSVPVLQRAGYTRYALAMGEYRSGN
                     NLQSSPKFIQGSLMHGLEGNWTPYGGMQIAEDYQAFNLGIGKDLGLFGAFSFDITQAN
                     TTLADGTRHSGQSVKSVYSKSFYQTGTNIQVAGYRYSTQGFYNLSDSAYSRMSGYTVK
                     PPTGDTNEQTQFIDYFNLFYSKRGQEQISISQQLGNYGTTFFSASRQSYWNTSRSDQQ
                     ISFGLNVPFGDITTSLNYSYSNNIWQNDRDHLLAFTLNVPFSHWMRTDSQSAFRNSNA
                     SYSMSNDLKGGMTNLSGVYGTLLPDNNLNYSVQVGNTHGGNTSSGTSGYSSLNYRGAY
                     GNTNVGYSRNGDSSQIYYGMSGGIIAHADGITFGQPLGDTMVLVKAPGADNVKIENQT
                     GIHTDWRGYAILPFATEYRENRVALNANSLADNVELDETVVTVIPTHGAIARATFNAQ
                     IGGKVLMTLKYGNKSVPFGAIVTHGENKNGSIVAENGQVYLTGLPQSGKLQVSWGNDK
                     NSNCIVDYKLPEVSPGTLLNQQTAICR"
     gene            39832..40362
                     /locus_tag="RHX21_001751"
     CDS             39832..40362
                     /locus_tag="RHX21_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDV1986949.1"
                     /translation="MKYNNVIFLGLCLGLTTYSALSADSVIKISGRVLDYGCTVSSDS
                     LNFTVDLQKNSARQFPTTGSTSPAVPFQITLSECSKGTTGVRVAFNGIEDAENNTLLK
                     LDEGSNTASGLGIEILDGNMRPVKLNDLHAGMQWIPLVPEQNNILPYSARLKSTQKSV
                     NPGLVRASATFTLEFQ"
     gene            40375..40878
                     /locus_tag="RHX21_001752"
     CDS             40375..40878
                     /locus_tag="RHX21_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDV1986950.1"
                     /translation="MKRLHKRFLLATFCALFTATLQAVDVTITVNGRVVAKPCTIQTK
                     EANVNLGDLYTRNLQQPGSASGWHNITLSLTDCPVETSAVTAIVTGSTDNTGYYKNEG
                     TAENIQIELRDDQDATLKNGDSKTVIVDEITRNAQFPLKARAITVNGNASQGTIEALI
                     NVIYTWQ"
     gene            40937..41851
                     /locus_tag="RHX21_001753"
     CDS             40937..41851
                     /locus_tag="RHX21_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV1986951.1"
                     /translation="MGKTISIKVLFGIYLLLMAGKVFAFSCNVDGGSSIGAGTTSVYV
                     NLDPVIQPGQNLVVDLSQHISCWNDYGGWYDTDHINLVQGSAFAGSLQSYKGSLYWNN
                     VTYPFPLTTNTNVLDIGDKTPMPLPLKLYITPVGAAGGVVIKAGEVIARIHMYKIATL
                     GSGNPRNFTWNIISNNNVVMPTGGCTVDSRNVTVDLPDFPGSAEIPLGVYCSSEQKLS
                     FYLSGATTDSARQVFANTAPDATKASGVGVSLMRNGKILATGENVSLGTVNKSKVPLG
                     LSATYGQTGNKVSAGTVQSVIGVTFIYE"
BASE COUNT        11058 a         9573 c        10467 g        10845 t
ORIGIN      
        1 cattttcccc aaccttgaaa aagcacaagc tatttttact ccggtaatga atggttctgt
       61 aaatatcatg tcaattatga ttgctttcct ggtcgccagg aatatggcga ttagctatga
      121 gcaagatgat cttttatgcg gattaacggc aataggagca ttttttattg tttatacgcc
      181 atatcagatg atagatgggc aagcattcct gacgaccaaa tatctcggcg cgcaggggtt
      241 gtttgttgct gttatcgttg cattgatcac cagtgaaata ttttgtcgct tagctcgaaa
      301 cccaaaaatc accataacga tgccggcagc tgtaccgcct gcggtagcgc gttcatttaa
      361 agttttattg ccaatatttt ttgtcatggt gttcttttcc gcacttaatt attgcctgac
      421 actgatatcc ccggcaggac taaacgatct tatttacaca ttaatccaga cgccgctcaa
      481 acatatggga acgaatatct ttgcggtaat tatcctgggg gctgtgggta atttcctgtg
      541 ggtgctgggg atccacggac ctaataccac atcggcaatt cgagaaaccg ttttttctga
      601 ggctaatctg gagaatctct cctgggccgc tcaacatggc actacctggg gcgcgccata
      661 tccgattacc tggacttcta ttaatgatgc attcgccaac tgcggcggtt caggtatgac
      721 gttggggtta ttgttggcta tttttatcgc ttctaagcgt gcggaatacc gtgatctggc
      781 aaaaatgtca tttatccccg gtattttcaa tatcaatgaa ccgataatgt ttggccttcc
      841 tattgtactt aaccccatca tgatggtgcc gtttattatg gttcccattg ttaactgtgc
      901 cattggttac ttctttgttt cgatggaaat tattccaccg gttgcttatg ccgtgccctg
      961 gactacgccc ggacctttaa ttgctttcct cggaaccggg gggaactggc tggctttact
     1021 ggttggtttt ttatgtttag gtgtggcgac aatgatctat ttaccttttg ttattgccgc
     1081 caacaaagtc aataacatga caactaacgg ataattccat ttacccagga aggagattgt
     1141 gatgtttgca gatgaagaac ttgttatgga gttactggtc aacgcggggc aggcacgttc
     1201 tgacgcgatg gaagccatac gttgtgccgg gcaaaaagac tggcagggcg caactcagct
     1261 aatggccagt tctgaatctg cctgtcttca ggcacataag attcagaccg cattaattag
     1321 tcaggatgaa ggctgtggca aaataaaagt taatttaatt ctgattcatg cacaggatca
     1381 tttgatgaat gcaatattat gccaggattt agccagggaa attatttcat taagaaaaga
     1441 actccatgcc tgattttttc ctccagtgcg atagctggag gaaattatta tactcttaag
     1501 gataagtcat gaatataaag acgcttaacg tcagcctttt gtctttttct attattacag
     1561 cattgtttcc attgaacgcg atggcaacaa aattaaccat agagcagcgc cttgaattgc
     1621 ttgaaaatga attgtcgcaa aataaacaag agctgaaagc aacacagaat gaactgggag
     1681 tatataaatc ccgactttcg accttacaaa aaagcatcac ggaaaacaaa tataaatcag
     1741 cctcgcttgc tgaaatatca gcgacatctc ccgtcgctga taacatcaaa aatgaaaacg
     1801 gtgaacagaa ctcgtctgcc gcagcgcata ctataaatgg atcgcagcaa gttgccgtta
     1861 ttgaaagtaa aggcgacaaa accactatcg aaagcgtgac cctgaaagat atcagtaaat
     1921 atataaagga tgatattggg ttcagctatc aggggtactt ccgctcaggc tggggtactg
     1981 gtaatcacgg ctcaccacaa acttatgcag cgggttctct gggacgtttt ggtaatgaga
     2041 tgagcggttg gtttgacctg accttaaatc agcgtgttta taatcaggac ggtaaaacgg
     2101 caaatgcggt cgttacctat gatggcaacg tgggtgagca gtataacgat gcctggtttg
     2161 gtgacagtgc caatgaaaat atcatgcagt tcagcgatat ttacctgaca acgcgaggtt
     2221 ttttaccctt cgcaccagag gcagacttct gggtcggcaa acataaactc ccgcaatatg
     2281 agatccagat gctggactgg aaaaccttaa ccacggatgt cgccgcgggt gtggggattg
     2341 aaaactgggc acttggtgta gggctgtttg atatgtcctt aagccgtgat gatgtcgatg
     2401 tttactctcg tgatttttcg cgtaccagcc agatgaatac caattctgtg gatgttcgtt
     2461 atcgcaatat cccgttatgg gatgatgcga cattatcatt aatggctaaa tattccgcac
     2521 ctaataaaac ggatcaacaa caagataacg aaaatgacaa cagttatttt gaaatgaaag
     2581 atagctggat gctgacttct gttttacggc aaaacctgca acgcgatacg tttaatgaat
     2641 ttacgttaca ggttgccaat aattcctatg ccagcagttt tgccagtttc tcagatgcca
     2701 gtaatacgat ggcgcatgat cgctattact atggtgatca taccaatggg atcgcctggc
     2761 gtttaatctc tcagggcgag atgtatctta ctgacaatat tattatggct aacgcgcttg
     2821 tctattctca cggcgaagat gtttatagtt atgaaagtgg tgctcatagt gattttgaca
     2881 gtattcgcac tgtaataaga ccggcctgga tctggaatac atggaatcag acggggcttg
     2941 aattaggctg gtttaagcaa cagaacaaaa ctcagcaggg tgtaacacta aatgaatcgg
     3001 cttataaaac gacactctgg catgcattga aagtgggtga aagcatttta ggttcacgac
     3061 cagaaattcg cttctatgga acgtatatca atattctgga taacgaatta tcgaatttta
     3121 agtttaatga gaacagcaaa gacgagttta tggccggcat ccaggcggaa gtctggtggt
     3181 aatctatttt agttaaggag ttgtgtatgt caggatttaa aaaaggtttt ttatggggcg
     3241 gtgcggtagc cgcgcatcag ttggaaggtg gctggaatga aggaggaaaa ggcatcagca
     3301 tcgctgatgt gatgactgct ggcgctcacg gggtgccgcg tgaagtgaca gaaggcgtta
     3361 tcgacgggct taattatccc aatcatgaag caattgattt ttatcatcgc tataaaacag
     3421 atattcagtt atttgccgag atgggattca aatgctttcg aacttccatt gcctggacac
     3481 gaatctttcc gcaaggtgac gaacaggagc cgaatgaaga gggtttacaa ttttatgatg
     3541 atctgttcga tgaatgcctt aagcagggaa tggaacctgt ggtgacgctt tcacattttg
     3601 agatgcctta tcatctggtg acaaaatatg gtggctggcg aaaccgtaaa ctgatcgact
     3661 tttttatccg cttcgcatca acggtcttca cgcgctataa agaaaaagta aagtactgga
     3721 tgacgtttaa cgaaatcaat aatcaggtga atttcagcga aagcctgtgt ccatttacta
     3781 attccggtat cttgtattcg ccagaggaag atatcaatga gcgcgaacaa ataatgtacc
     3841 aggcggtaca ttacgagtta gttgccagtg ccctggcggt acagactgga aaatcgatca
     3901 atcctgaatt taacattggc tgtatgatcg ccatgtgtcc catctatcct ctgacgtgtg
     3961 cacccaacga tatgatgatg gccacgaaag caatgcatcg tcgttactgg tttactgatg
     4021 ttcatgctcg tggatattat gcgcaacata tgctgaatta ctttgccagg aaaggattca
     4081 acctcgatat cacaccagaa gataacgcga ttcttgccag tggttgtgtc gactttatcg
     4141 gctttagcta ctacatgtct tttacgacac aattttcgcc cgataacccg caactggatt
     4201 atgttgaacc acgagatttg gtcagcaacc cttatatcga tacatccgaa tggggatggc
     4261 aaattgatcc ggcagggcta cgttattcac tcaactggtt ctgggatcat ttccagttgc
     4321 cgctgtttat tgtcgaaaat ggatttggtg cggttgacca gagacaagct gacggcacgg
     4381 tgaacgatca ctatcgcatt gattactttg cttcccatat tcgggaaatg aaaaaagccg
     4441 tagttgaaga tggtgttgac ttaattggct acaccccgtg gggctgcatt gacctggttt
     4501 ctgccggaac aggggaaatg aaaaagcgct acggaatgat ttatgtcgat aaagacaacg
     4561 aagggaaggg aacgctggaa cggatacgta aagcgtcgtt ttactggtat cgggatctca
     4621 tcgccaacaa tggcgaaaat atttgagact tgaggaagat attacggaga tgtcaggctc
     4681 tgtgatcaga gcctgacaat aactacatag cgtgttgatt ataatagggc acgccgagcg
     4741 catccgactt atcactgcca gtacccatgt gatttaaatc aaacggtggt tgttcctgcg
     4801 atgggggaac aaccacgaca ttggcacaag aagtaacaac tggctgcgtg gtttgttccg
     4861 caacgccctg cgcggaaaag agaataagcg cagctgctat tgcggatgaa agtggtttca
     4921 tgatagcctc agtgacgttg tcacgttatc aactagctgt tgtaatgatt taatggatgt
     4981 aaaaagcgcg attcgccctg catattggtc atccggtatt tatgcggcgg aacatcaaag
     5041 taatttttga aggttcgggt cagagtttgt tgcgactcga agccatatcg ttctgccaga
     5101 tagagtatcg gctcgttact ttccttcagc ttttgcgcga tttccgtcat cttacggctg
     5161 cggatgtatt ggcctaatga atgaccggtt tcttttttaa acatccgttg caggtgccat
     5221 ttagagtaac ctgaacgctc tgacactttc tccagtgaca gtggcgattc caggttgtcc
     5281 tcgatccagt ccaaaatgct atgaatggta atagcgtcag tattgcgtct ggacatcgtc
     5341 atacctcttt tttgtttacg gcaggacttt cttaagcaaa tgctcaagtg ttgccacttc
     5401 gtccgccgtc aggttttttg ttaattcttg gtgcaggtcc tggccaacta attgatggca
     5461 ttgttcacat attgccgcgc cgctggtggt aagttttacc agtacgccgc gcttatcatt
     5521 cgggttcggc aacctttcaa cccagccttt acagaccagg cgatccagca tacgggtgag
     5581 tgctcccagg tcgaccgaca acactttttt cagttcaacc ggagtaatac acgccgcgca
     5641 gcggatagag cagagcacct taaactgtgc cgcggtaata tccagcggag acagatactc
     5701 gttaagcaga cgatctttct tctgattaac catatggatt aagcgaccca atggaataat
     5761 ttcattgaac agatcgctgg tacttttcac attagttgcc ctggcaagta attagttgca
     5821 ggggataata ttgcccaggc aagtataagt caaatgaatg aattgaccga tgccacgttt
     5881 tgctaaatcg gttcaagttt tggtcaatgc gatgtaaggc tagctaaaga gtgacacttt
     5941 atccttgttt accccttata cttttcgctg ataacccaga tacacaggat aacaaccacc
     6001 aatgttagat ttgtttaaag caattggcct ggggctggtg gtgttgctgc cgttagctaa
     6061 cccattaaca actgtcgcgc tatttcttgg tctggcaggc aacatgaaca gtgccgaacg
     6121 taatcgtcag tcgttgatgg cctcggtgta cgtatttgcc atcatgatgg tggcgtatta
     6181 cgccgggcaa ctggtgatgg atacatttgg catttcgatt cccggtctgc gaattgcagg
     6241 cggcttaatc gtcgcgttta tcggttttcg gatgcttttt ccgcaacaga aagcgattga
     6301 ttcaccggag gcgaaaagca agtcggaaga gctggaagat gaaccgagtg ccaatattgc
     6361 ctttgtacca ctggcaatgc caagtaccgc cggtccggga accatagcga tgattattag
     6421 ctcggcgtcc acagtgcgtc agagttcaac cttcgctgat tgggtactga tggttgcgcc
     6481 gccgctgatc tttttcctgg ttgcggttat tttgtgggga agcctacgca gctccggcgc
     6541 aattatgcgg ctggtgggca agggtggcat tgaagcgatc tcccgtctga tgggattcct
     6601 gctggtatgt atgggtgtgc agtttattat taacggcatc ctggaaatca ttaaaacgta
     6661 tcattaaaaa aggcccgaat gggcctttca actattgcgt ctgttcttcg agtgtcactg
     6721 gccagcggcg aaatataatg attgaccaaa ttaacgcggc aaaagcaggc accgcgccca
     6781 cataaccaat catcgacatt gaccagtgca gactcacctg attacctacc aacgcacccg
     6841 ccccgattcc aatattaaat atcccggaga atagcgccat cgcgacgtcg gtggcatctg
     6901 gtgccagcgc cagcacttta acctgcatac caagcccgat gatcatcatc gcgatccccc
     6961 agaaaatact cagcaccccg aggtgtattt cactgttcgc cgcaggtagc agcagtgcca
     7021 ggcacaccag caacagcgca atcgccgtac ttaccaacgc agacgcatac tgattaccca
     7081 gtttaccgaa aattacgctg ccaataatgc ccgcaccacc gagtaataac agtaatgccg
     7141 tggcaaagtt ggcgctgaat cccgcaatgt tttgcacaaa aggctcgata tagctgtatg
     7201 ccgtgtaatg ggcggtgaca accaccacag ttaacaaata aatgctcatc aatgccgggc
     7261 ggcggaacaa tagcgggagg cttttcaatg aaccggaatg ctcactgggc agtaagggaa
     7321 gtaacttaat caggcacaaa agggtgataa gcgccgcaat accaatcgcg aagaaggtca
     7381 ttcgccaacc gaaatactgg cccacaatac gcccgagagg taaacctaag accatcgcca
     7441 gtgctgtacc ggtggcaatt aaactcaatg cctgtgctcg cttcccggcc ggagccatac
     7501 ggatcgccag agacgccgta atcgaccaga aaatcgcatg cgcaaaagcc acaccaatgc
     7561 gactgatcac cagaacggta aagctccacg ataaaaacga cagtacatgg ctggcaataa
     7621 acaccacaaa caggcagatc agtaatttgc gccgttcaac ctggctggtc attaacataa
     7681 aaggcaatga cattagcgcc actacccatg cataaatggt caacataatg ccgacctgag
     7741 cggtttgcat gtgaaaactt tgcgcaatgt cagagagcag gccaacaggg acaaattcgg
     7801 tggtgttgaa gatgaaggcg gcgactgcca gcgtaacgac ccgtagccac gccactttgc
     7861 gggaaacagt gtttgttgtc ataacagatt atcgggtgag ttgcgaaaaa gtgatgaaat
     7921 gatcttaaaa cggttaatga tgtgaataca atgcatttgt gatctggatc gcgttttccg
     7981 tttctctgac gctgattctg ttccgcgtca gagagtcggt aacatcacgg tttaatgacg
     8041 ttcagggagg tctggcgttt tggcgattgc gggtataggt ggtctgacag gggagcgagg
     8101 cctgtttttc accaggtctt cgtgagtaac ttttggcggc gtttcatttt tacaaacagt
     8161 ttgagggtcc tgcgcgccat atgtttgata attttatcat cacttaatga tgctggcatc
     8221 aacacgtcat tcagatcact ttcattggga ttcataaatt ggtgatagtg caataacata
     8281 ttggcgaaaa ataaaaaaaa gtcctgaaaa tgaggagatt cttgttctgc taaaagggat
     8341 aaaaagcaga tgcagacttc gggtagtaca tgtttgttag aacctaatga atccatcagg
     8401 ctttgcaata aatcctcttt taattcgctg tccgttatgt cgagaatggc ggtgttcaag
     8461 ttaggatctt tattgacgaa ccatctgtga acctcagagt tattccataa tcgggggagt
     8521 atgacaaaat taccgcgaga gataaaattc aggacaagca aatcaaactg gcgtaagtaa
     8581 tctgcagcgg tatggtgatc cggaggcagg ggttcaatat gtggtgtatg cgctcttttg
     8641 atgggaacgc caaggttgat cattggaaat tgttcaataa aatcattcag aaacagaaat
     8701 agcacacgct cgacgccggt ctgaaatacg cgccccatag tgacaggctt tgggttggga
     8761 gcgcaaaaat attaatttct ccatcatggc gaaaattatc taaataaata gggcttaaat
     8821 ttattactac ctgaaattca atattttctt tgtgtcttcc attcttgacg ggataagtga
     8881 gtttaaactg aaccttttca ttgtatagcg tgtcgttacc ccgaaaagaa gtcctctgaa
     8941 tatatgataa gttatcaagg ttattaaata tcttttttgt ggctgagttg atgtttaaag
     9001 acgtgcgcca ctcttcatca catattattg tacttagcgc atcaataaag tcctttaaaa
     9061 cttcttttac ctgaggtgca atattacgta cgggaaaatc atcaggaaga gatatgtaat
     9121 tactgatgct tactggcgta accatatttg ccccatatag tcataagtca tcggaacatc
     9181 actatatagg gcatttgagc tgcaagaact atcaaaaata gctcattggt aaccctgttt
     9241 tgccgagtca ggcacatcca gtagttgaat aaatgcctca agcggacgcg ttttcgcacc
     9301 acgacgccag accagccagg ttgttaacca acgccattgc tcagctaacg gccacgcttc
     9361 aacctggtga tgccccggca tactttccag catagagcgt ggaataagcg caatgcctgc
     9421 tcctgcgacc acacaggcca acattccgtg ataagactcc atctcatgga tagttcccgg
     9481 agcggcaccg tcagcatgaa accagctctc gaagtggcga cgatacgaac aattggcgcg
     9541 gaaggcataa atgttactgc cgttaacctg actggcgcgg attactggcg catgaccttg
     9601 tggcgtgacg atcatcagct cctcgcggta taccggtatc ccgtcaatgg cagtatggtt
     9661 aatgggccca tcaataaatg ccgcattcag ttttccctcc agcactcctt ccagcatagt
     9721 gccggaaggg ccggtggaaa gtgaaaactg aattttggga taacgatggt tgaattccgc
     9781 cagcgtggcc ggaatgcgca ctgctgcggt gctttccagc gaaccaagag aaaataaacc
     9841 ttgcggctca tcgccagcga caacgctccg cgcttcatcc actaacgcga gaatttgttg
     9901 gctatagcgt aaaaagttat gcccggcagg agagagacgt aaacgctgat tctcgcgaat
     9961 aaacagatca acccccagtt ctgtttccag ctggcgtaga cgggtagtga gattcgacgg
    10021 cacgcgatgc acttttgctg cagcctgggt tatgctgcca gcttcggcaa ccgcgttgaa
    10081 catctccagt tgggtcagat ccataatatt ctcgattcgt gaataagtgg cttaatatta
    10141 ttcattttaa agcaagagta aatctgcgta tcttcatacc atgactcata aaggagatac
    10201 cccgatgacc attactccgg caactcatgc aatttcaata aatcctgcca cgggtgaaca
    10261 actttctgtg ctgccgtggg ctggcgctaa cgatatcgaa aacgcacttc agctggcggc
    10321 agcaggcttt cgcgactggc gcgagacaaa tatagattat cgtgctgaaa aactgcgtga
    10381 tatcggtaag gctctgcgcg ctcgtagcga agaaatggcg caaatgatca cccgcgaaat
    10441 gggcaaacca atcaaccagg cgcgcgctga agtggcgaaa tcggcgaatt tgtgtgactg
    10501 gtatgcagaa catggtccgg caatgctgaa ggcggaacct acgctggtgg aaaatcagca
    10561 ggcggttatt gagtatcgac cgttggggac gattctggcg attatgccgt ggaattttcc
    10621 gttatggcag gtgatgcgtg gcgcggttcc catcattctt gcaggtaacg gctacttact
    10681 taaacatgcg ccgaatgtga tgggctgtgc tcagctcatt gcccaggtgt ttaaagatgc
    10741 gggaatcccg caaggcgtat atggctggct gaatgccgac aacgacggtg tcagtcaaat
    10801 gattaaagat tcgcgcattg ctgctgtcac ggtgaccgga agtgttcgtg cgggagcggc
    10861 tattggcgca caggctggag cggcactgaa aaaatgcgta ctggaactgg gcggttcgga
    10921 tccatttatt gtgcttaacg atgccgatct ggaactggcg gttaaagcgg cggtagccgg
    10981 acgttatcag aataccggac aggtttgtgc agcggcaaaa cgctttatta tcgaagaggg
    11041 aattgcttct gcatttaccg aacgttttgt ggcagctgcg gcagccttga aaatgggcga
    11101 tccccgtgat gaagagaacg ctctcggacc aatggctcgt tttgatttac gtgatgagct
    11161 gcatcatcag gtggagaaaa ccctggcgca gggtgcgcgt ttgttactgg gcggggaaaa
    11221 gatggctggg gcaggtaact actatccgcc aacggttctg gcgaatgtta ccccagaaat
    11281 gaccgcgttt cgggaagaaa tgtttggccc tgttgcggca atcaccgttg cgaaagatgc
    11341 agaacatgcg ctggaactgg ctaatgatag tgagttcggc ctttcagcga ccatttttac
    11401 caccgacgaa acacaggcca gacagatggc ggcacgtctg gaatgcggtg gggtgtttat
    11461 caatggttat tgtgccagcg acgcgcgagt ggcctttggt ggcgtgaaaa agagtggctt
    11521 tggtcgtgag ctttcccatt tcggcttaca cgaattctgt aatatccaga cggtgtggaa
    11581 agaccggatc tgacgcgaca tattcagctc tgatatactc gcaggtcttt tcagacctgc
    11641 ggtccaggag tagaaagtgg cagtcgccat ggataatgca attttagaaa acatcttgcg
    11701 gcaagtgcgg ccgctcattg gtcagggtaa agtcgcggat tatattccgg cgctggctac
    11761 agtagacggt tcccgattgg gcattgctat ctgtaccgtt gacggacagc tttttcaggc
    11821 cggagacgcg caagaacgtt tttccattca gtctatttcc aaagtgctga gtctcgttgt
    11881 cgccatgcgt cattactccg aagaggaaat ctggcaacgc gtcggcaaag atccgtctgg
    11941 atcaccgttc aattctttag tgcaactgga aatggagcag ggtattccgc gtaatccgtt
    12001 tattaatgct ggtgcgctgg tggtttgcga tatgttgcaa gggcgattaa gcgcaccacg
    12061 gcaacgtatg ctggaagtcg tgcgcggctt aagcggtgtg tctgatattt catacgatac
    12121 ggtggtagcg cgttccgaat ttgaacattc cgcgcgaaat gcggctatcg cctggctgat
    12181 gaagtcgttt ggcaatttcc atcatgatgt gacaaccgtt ctgcaaaact actttcatta
    12241 ctgcgctctg aaaatgagct gtgtagagct ggcccggacg tttgtctttc tggctaatca
    12301 ggggaaagct attcatattg atgaacctgt ggtgacgcca atgcaggcgc ggcaaattaa
    12361 cgcgctgatg gcgaccagtg gtatgtacca gaacgcgggg gagtttgcct ggcgggtggg
    12421 gctaccggcg aaatctggcg ttggtggcgg tattgtggcg attgttccgc atgaaatggc
    12481 catcgctgtc tggagtccgg aactggatga tgcaggtaac tcgcttgcgg gtattgccgt
    12541 ccttgaacaa ttgacgaaac agttagggcg ttcggtttat taatgcagtc tctcgatcca
    12601 ctcttcgcgc gtttatcccg ttcaaaattt cgctctcgct ttcgtctggg catgaaagag
    12661 cgtcagtatt gcctggagaa aggcgcgcca gtcatcgaac aacatgcggc ggattttgtc
    12721 gctaaacgtc ttgctccggc attaccggct aatgacggta agcaaacccc catgcgcggg
    12781 catccggtgt ttatcgctca gcacgccacc gcgacctgct gtcgcggttg tctggctaag
    12841 tggcataaca ttccgcaggg tgtttcgtta agcgaagaac aacaacgtta tatcgtggcg
    12901 gtaatctatc actggctggt tgtacagatg aatcagccat gagaattgcg gaaaacgata
    12961 aaatagcatt cccagggtac ctttatttgc cgccgctgtt agcgaacatg ctatccttta
    13021 tgagaattta cttattacgt tgagataatt gccacccgca attgtatgga cagataatta
    13081 atgcatgtac accccatttc aactttccgt ttgttccagg aaggtcatct gctacgtaat
    13141 agcatcgcta tttttgcgct aaccacgctg ttctatttta ttggtgcaga gttacggctg
    13201 gttcacgaac tttctctttt ctggccgctg aatggcgtaa tggcgggggt gtttgcccgc
    13261 tatgtctggc ttaatcgact gcattactat gcgatcagtt atgtggcgat gctggtttat
    13321 gatgccataa ccaccgaatg gggactggtt tcactggtta tcaatttctc caatatgatg
    13381 tttattgtta ccgtcgcctt actggtcgtg cgggataagc gtctggggaa aaataagtat
    13441 gagccagtaa gtgccttacg gctatttaat tactgtctca ttgccgcatt attatgcgct
    13501 attgtcgggg cgattggttc ggtcagtatt gatagtctgg atttctggcc tttgcttgcg
    13561 gactggttca gtgagcaatt ctcaacgggc gttttgatcg tgccttgtat gctgacgttg
    13621 gctattcctg gagtgctgcc gcgctttaaa gcagaacaga tgatgcccgc catcgcgctt
    13681 attgtgtcgg ttattgcctc ggtagtcatt ggcggagcgg ggagtctggc gttcccgctg
    13741 cctgcattaa tctggtgtgc agtgcgctat acgccgcagg taacatgtct gttgaccttt
    13801 gtcaccggtg cggtggaaat cgtactggtg gcaaattcgg tgattgatat ctcggtcggt
    13861 tcgccgttct ccattccgga aatgttctcc gcacgtctcg gtattgccac gatggcgata
    13921 tgcccaatta tggtttcttt tagcgtggca gcgatcaatt cgctaatgaa gcaagttgcg
    13981 ctgcgagccg actttgattt tctgactcag gtttactcac ggtccggtct ttatgaggcg
    14041 ctgaaaagtc catcgctgaa acagacacaa catctgacgg tcatgctgct tgatattgac
    14101 tatttcaaaa gcattaacga taactatgga catgaatgtg gcgataaagt gttaagcgtg
    14161 tttgcccggc atattcagaa gattgtcggt gataaggggc tggtggcgcg catgggcggc
    14221 gaagaatttg ctgttgcagt gccgtcggtg aatcctgtcg atggtctgct aatggcggaa
    14281 aaaatccgta aaggcgttga actgcaacca ttcacctggc aacaaaaaac gctttatctc
    14341 acggtaagta ttggcgtcgg tagtggtcgc gcatcgtacc gaacgctgac cgatgatttt
    14401 aataaattga tggtcgaagc cgatacgtgt ctgtatcgct cgaagaaaga tgggcgcaac
    14461 cgtaccagca ctatgcgtta cggtgaggaa gttgtctgac atctttattc attccgcgcg
    14521 atttgaatgc aatgtgttct accactttat gatccaggaa aaggcgtatt tcctcgatta
    14581 aaccatgatc cgcgccacac ttttctcata aaactgctca ttaatcatca ggagttgatc
    14641 aaaacagggg ttcggcgtat taaagtttgc taacctgtcg taccaattca aacaggttgt
    14701 atgactaatc agaagggaac ccattgtgaa aacactaaat cgtcgcgatt ttcccggtgc
    14761 acagtatcca gaacgtatca ttcagtttgg tgaaggtaac ttcctgcgcg cctttgttga
    14821 ctggcaaatc gatctcctga atgagcacac cgatctgaat tctggcgtgg tcgttgttcg
    14881 tccgattgaa acttcattcc cgccgtcact gagcacgcag gatggtctgt acaccaccat
    14941 tatccgtggc ctgaatgaga agggggaagc ggtcagcgac gcgcgtctga ttcgctctgt
    15001 taatcgtgaa atcagcgtct acagtgaata cgatgaattc ctgaaactgg cgcacaatcc
    15061 ggaaatgcgc tttgttttct ctaacaccac cgaagcgggt atcagctacc atgcgggcga
    15121 taaattcgat gacgcgccag cggtaagcta tcccgcaaaa ctgacccgtc tgctgttcga
    15181 acgttttagc catttcaacg gtgcgctgga taaaggttgg atcatcatcc cgtgtgagtt
    15241 gatcgactac aatggcgacg cgttgcgtga actggtgctg cgctatgctc aagagtgggc
    15301 actgccagaa gcatttattc aatggttgga tcaggctaac agcttctgtt ctacgctggt
    15361 ggaccgtatc gttaccggtt atccgcgcga tgaagtggct aaactggaag aagaactggg
    15421 ttatcacgat ggtttcctcg acaccgctga acacttttac ctgtttgtga ttcaggggcc
    15481 gaaatcctta gcgactgaac tgcgtctgga caaatatccg ctcaacgtgc tgattgttga
    15541 cgatattaaa ccgtacaaag aacgcaaagt ggcaatcctc aacggtgcgc acaccgcgct
    15601 ggtgccggtg gcgttccagg cagggctgga taccgtaggt gaagcgatga acgatgctga
    15661 aatttgcgca ttcgttgaaa aagctatcta cgaagaaatt attccggtac tggatttgcc
    15721 tcgtgatgaa ctggaatctt tcgccagtgc agtcaccggg cgtttccgta acccgtacat
    15781 taagcatcag ctgctgtcta tcgcgctcaa cggtatgacc aagttccgca ctcgcatcct
    15841 gccgcagctg ctggcagggc agaaggcaaa aggcacactt ccggcgcgcc ttactttcgc
    15901 attagcggca ttgattgcct tctatcgtgg tgagcgtaac ggagaaacat atccggtaca
    15961 ggacgatgca cactggctgg aacgttatca gcaactctgg agccagcatc gtgaccgtgt
    16021 tatcggtacc caggaactgg tagcgattgt gttggcagaa aaagaccact gggagcagga
    16081 cctgacgcaa gtgcctggtc tggtcgagca ggttgctaat gacctggatg cgattcttga
    16141 aaaagggatg cgcgaagctg tacgtccgtt gtgctaataa caccgttact tctgaacccg
    16201 gtttcgaccg ggtttcttat ttcactatat tagttacaac atcctatgtg cctttatcat
    16261 taacagatgc cacatgcagc gcctgttaat gttgtaagct tgtaggtaat ttgtaagtag
    16321 cgtcttgaga atgtgatcgt aatcacgttt aatagggcga ctttttcacg cctgaagata
    16381 accatgattg ttcgtccaca acaacactgg ctgcgccgta tttttgtctg gcacggctca
    16441 gtattatcca agatatcatc gcgcttacta ctcaattttc tcttttctat cgctgttatt
    16501 ttcatgctgc cctggtacac gcatctgggc atcaaattca ccctcgcacc gttcagcatt
    16561 ctcggtgtcg ccatcgccat ttttcttggt tttcgtaata atgccgggta cgcccgttac
    16621 gttgaagcgc gaaaactttg ggggcagttg atgattgcct cacggtcgtt actgcgcgag
    16681 gtaaaaacga cattgccgga ttcggcaagt gtaagggagt ttgcccggtt gcaaatcgcc
    16741 ttcgcccact gtttacgcat gacattacgc aaacagccac aggcggaagt gctggctcat
    16801 tatctcaaga ctgaagatct tcagcctgta ctggcttcga actctccagc taaccgtatc
    16861 ttgttaataa tgggggagtg gttggcggtt cagcgccgca atgggcagct ttcagatatc
    16921 ctgtttatta gcctcaacga tcggcttaat gatatttcag cggtcctggc aggatgcgag
    16981 cgcattgcct atacgccaat tccctttgcc tacaccctga ttttgcatcg taccgtttat
    17041 ctgttttgta tcatgctgcc gttcgcgctg gtcgtggacc tgcattacat gacgcctttt
    17101 atctctgtgc tgatttccta cacttttatt tcgctggatt gtctggcgga agaactggaa
    17161 gatccgttcg gtactgaaaa caatgattta ccgctggatg ccatctgcaa cgctattgaa
    17221 attgacctgt tacagatgaa cgatgaagcc gaaattccag caaaaattct tcccgatcgt
    17281 cattaccagc tgacgtgata tttactccat acgccgggca acaataaaaa gacgcggaaa
    17341 tgccagcagt atctgtccgt tctcttgcag tggatactgc tcttccagca tctgatggta
    17401 gcgcttaaga aaaagctgct gttcgctctc ggtcagatcc tgtaaccacg gacgtaatcc
    17461 agtggcggtc acccaatcga taatcgcctg gtgtgacggc atctggtgat agtaggtggt
    17521 tcgccagata tcgacctcac atccggcttc gctcaaaata tcgtagtaag catgaacgcc
    17581 agccaacggc tcacgcccgc gatccgggta gttttgttcc caggcaactt cgcgcatgag
    17641 cacatgggtc ggctccagcc agttatctgg catctgtact gccagcacgc cctgcggatt
    17701 aagtaaagaa accagatgag gaaacaattc gtagtggtcg ggcagccatt gcagtgaggc
    17761 attagcaaaa atcagatcga gtgcctgtac cggttgccag ttgcggatgt ctgcttccac
    17821 gaactggcag tctggcaaag cactgcgcgc ttcagcaatc atcgccggag acgagtcgat
    17881 gcctgttatc ctggcagcag gccaacgttg gtttagaagg gcggtgctgt tacctgggcc
    17941 acagccaaga tcggcaacgt attcgatatt ctccagcggt actctggcaa gcagctccac
    18001 cgccggacgc gatcgttcag cggcaaagtg cagatataaa gaggggttcc agtcagacat
    18061 ttatttactc ccgtcagcgc gttaccccaa ttgtagataa aactgatgaa ttcgcctcac
    18121 ggcatcaacc cattgaacag acgtttttta cgcggcccgg tcattaaaga ttccagtttc
    18181 gcgacacagg ttttgtagtg gggcgtggtt ttatggaatg ccactgcgtc ttcatcttta
    18241 taggcttcgt agatataaaa gcgcgaattc acttctgggt cctgtaagac atcgaagcgc
    18301 aaattgcctt cttcctgtac agagcccagg tggttctggc gaaaaacttc gataaactcg
    18361 tcaatcttgt cttcatgaac gttaatttca accagtgtga cgtgcataat tcttctcctt
    18421 aaatccgcag ttactgtttt tcactcagat agagttcata tgcccgatca gccgtttcgt
    18481 tatggtgaac caccgcctgt acggctttca tcatcgccac cggatggtca gactggaaaa
    18541 tattacgccc catatccaca ccagaagcgc cctgatcgat agcctgccag cacatttcca
    18601 gcgcctcgcg ctccggtaat tttttaccgc cagcaataac aatgggtacc ggacatccgg
    18661 caacaatccg ttcaaaacct ttttcgacat aataggtttt gataatttgc gcccccattt
    18721 cagcggcgat tcgagtcgcg agcgagaaat aacgctgatc gcgcaccata tctttgccca
    18781 cgccagtcac ggccatggtc ggcattccca ctttcattcc ggcatcgacc agctgaataa
    18841 tatttttgat cgactgatgt tcatattcgc tgccgatata aacctgcgcc gccaccgcgc
    18901 aactgttcag gcgcacggcg tcatccatcg ataacgccac ggcttcatta cttaattccg
    18961 ccagaataga gttcgcacct gacgcccgca gtaccaccgg cttattggtc gctgggggaa
    19021 ctacgctgcg caaaatgccg cgcgtacaca ttaatacatc ggcatgttca aacagcgggg
    19081 cgatatttat atcaatgcgt tcaagtccgg tagtcggccc ctgaaaataa ccatggtcaa
    19141 aggccagcat cacggtttta cccgttttcg gattaaatat ccgcgataag cgtgactgca
    19201 ttccccaatc cagcgcaccg caacctttta ggataaaagg gatattttgt tgcggttgat
    19261 cggtacgaaa atctttacca tctttaatat cgtctaaatc tgccataact tactccggtt
    19321 aagtaatgca catcagaaat cgtatttgcc gatattctct ttgttgaata tcacgcgctc
    19381 cggtaacagt acgatgccat taccatccgc ttcgtagtca tagccctgaa cgctgtttgg
    19441 cgagacttcc acctgaccta cgccctggat atccagcttg tcgcccgttt tcattgatcc
    19501 ttttttcaat aatgcatccg cgacatacac tgaaattttg ccttgctgaa ccacatccca
    19561 caggccaaat tctttcaccg tgccgcgttc cacatatgga cgcatcacgt ttggcgtact
    19621 gaatccgaca atcgcaactt tgtcattttt caggttttct gcggcttgtg cggcagcggg
    19681 cagggcgttg gcgtcggggg cgataatggc gtcgagatcg ctatacgctt ttaatattcc
    19741 ttctgcggtt tgtaatgatt tagtggcatc gttatagcca aactgcgtag tgacaatttc
    19801 ccagccagga tgctctttgg cgattttcgc tttcgcttct ttcacccact ggttttggtc
    19861 cgtaacggtg gggcttgagt agaaaaacgc gactttggct ttgtctttat tcacctgacg
    19921 cgccgccata tccaccaaca tacctcccaa ctgggcgggc gttccctgat taatgtagta
    19981 agagcggcac tccggtttag tatcagagtc ccaggtcagc actctcacac cacgttgcat
    20041 ggcgcgtttc agtgccggac acaagccatc aggcgaaacc gcagaaacga taatggcgtt
    20101 ataaccttga ttgacgaagt tattaatcaa ctgtacctga ccagaaacac tgggttctgt
    20161 cggcccgtcg taggtcacat caacgctcag ctctttaccc gcttgttgtg cgccgttgcc
    20221 accgctggta aaaaatccca cgccaaccag tttgggaata aatgcaatac gctctgcggc
    20281 ctgcacattc atagagattg cggcaatgcc aagagcgcta agtaaggcga ttttcttaaa
    20341 gcgatgaagt gtcatgaaga tatcctttat ggcaatgggt tattggcccg acgcgccagc
    20401 cactctttaa tttgctggcg atgcaggcta acggaacgac ctacgacaac gacgataagt
    20461 agcgcaccgg aaagggcgct ggacacctga tttggcactc ctgccatttg caaaccttgt
    20521 tgcaaatatc ccactaataa aaccgcaatg gcggtgccga taatggaacc ggaaccacca
    20581 taaatattgg caccgccaag caccacggcg gtgatggcgg gcatcagaaa cgacgcaccg
    20641 agatcggaac gtgctgaacc aaaatacgac accagcagca cagcggcgac cgcagacgcc
    20701 agccccgtca tggcatagag cgcacataag gtgcggttaa ctggaatcgc gctataaagc
    20761 gccacgcgcg ggctttgccc aatcaaaaac acattacgtc cggcatgggt tttatgcagc
    20821 cagagccaga aaacgaggag acatatcagg aagataatca gcggaacggg gagtcccagc
    20881 acatccaggt tagcgaaatc tgtaaacgcc atcgggaatc caccaatacc ttcgtacccc
    20941 gtcgctccgg ccataccgga aagcagcaga gcgcttccgg caaacagata cagcgtgcca
    21001 agcgtaatca ccagcgggtt aactttggta tagataatta atccggcgtt gatcagcccg
    21061 cacaatgcgc cgagcagtaa ggtcaggagt atcgccagcg gcatcggcac accactttga
    21121 aacagtacgc ccaatgcaat ggcgcagagg ccgatggtcg aaccaaacga aatatcgatc
    21181 ccgccactga caatcaccat cgtcagcggt agggcgacaa tgccaatgca gataaagtca
    21241 ctggtgctga acagcaacat attgagatct aacatccgcg ggttaattgc accaaatgcg
    21301 acaatctcaa taacgagcag tgcggcaaga gccagttccc aaccgtagcg aatacgcatt
    21361 atgcggcctc ccgattttta cctgacgaag cgggtttaac ggatggcggt ggcgtcataa
    21421 agcgggcata tttttgccgc cgtagattac gttccagcgc acaacgcagg cgtccatcaa
    21481 acaccagcac cgccagcagc acgaggcccg cgataaaatc gttccaccat gccggaatgc
    21541 gcaacagcac cagtacgcta tcgatctgcg tcaggaacca tgcgccgagt accgcaccaa
    21601 tgatcgcacc ggaaccgccg agcaaactaa tgccgcccag cacgcaggct gcaattgctt
    21661 tcatctccag cccggtaccg gtctggttgg ggataaaacc aatctgcgaa gcaaacacaa
    21721 ttcccgccag tgccgccatg cagccgttca acgaaaatgc cacaatgcga atggcttccg
    21781 tacgaacacc cagttgacga gcgccctgta aattatcgcc cgtggcataa aaactgcgtc
    21841 caaacgccgt ctttgccagc agccaggcca taaatgccac cagaattatc gtcaaccaac
    21901 caatcgcgga aacgccaaac agcagcggtg cggagagctc tttcagttcg gcgggtaacc
    21961 cttcaatcca tttgccgcca gtccacagca acatgatgcc tctgtacaac cctaacgtgc
    22021 caagggtggc aacaatggca gggatcttta gccacgcgac caggacaccg ttgaaaaatc
    22081 ccgcgagcaa accaagcagt aaagtcgcga cacaggcaac aggtagtgaa tatcctgcgt
    22141 tcagtaacat ccccaacagc accgcgcaca ttccggtaat cgaacccact gaaacatcaa
    22201 tattgcgcgt aagcattacc agcgtcgcgc ccattgccag taggatcagg atttgcgcgc
    22261 tgctataaac catggtcagc gtttgcacac ttaaatactg gcggtcgaga aaaccgggga
    22321 atacaaacag cagcaccacc gccagcaatg ccgtgatttc acggttgttc tgaataaact
    22381 tcagcatgat gcctcctgac gctgactatc gccgaaggca acgcgcataa tagtctcgac
    22441 attaatatcg cgcccggtca gtgcagagtg ggtaatttcg ccctgatgca tcacatacac
    22501 acgatctgcc atcagttcga tctcttccag atcagaggag ataagcagca cagccacatt
    22561 ctgtgcggcg atgctgcgca acagctggta gatatcatta cgtgccgaga catccacgcc
    22621 gcgcgtcggc tcatcgacaa tcaatacttg cggcgaagct tccaggcatt tggcaatgag
    22681 gattttttgc tggttgccac cggataatgt ccgtgcagct tgttccggtt ggttaaattt
    22741 aatattcagc gcccgacgat aacgttccag ggtggcatta tctttcgcgg ttttcgccca
    22801 gaatccacga aggttatgag taagggcgca gacgttccag gccagcgaag catcgagatt
    22861 cagtccggat gactggcgat cttccggcag ataaaccaga ccgcgcagta aacgttctcc
    22921 agtggataat ttattgatct ctttaccatt cagcataatg cgtccgccac gcaaagtacg
    22981 cagaccatag agcgtctcgg ccagttctgt gcgtccggct cccaccagcc cagccaggcc
    23041 cagaatttct ccggcattga gcgtcaggct gacattcctg aaaccttcgc cggtcagatt
    23101 ttccagtgtc agcaccggcg ttccggcagc atgttgtggg cggttaccag gtaactccag
    23161 ccataatttt tggctggcag agagcgattt ttcccgtacc gctggggtga tggcctgaat
    23221 aatgtcgtcg gtagacagtt cgctggtttt gccgcttaag gcgatggttc cgtcgcgcat
    23281 cacgctaatt cgatcggcaa tctggcgaat ttccggcagc ttatgcgaga taaaaacaat
    23341 acccacgcca gtagcaagca gctcttgcaa gcgactaaac aagcgttcgg tttccgcagg
    23401 ggtaagcgag gcggtaggtt catcgaggat cagaatccgc gagtcgcgca tcagcccgcg
    23461 gaggatttcc accatttggc gatcggcgac atccagcgat cctgccagac tatgcagatc
    23521 aaactggcag cccagcgccg ccagcaagtt cttcattttt tgcatggaga gctgtttttt
    23581 tgccatccca aacaggatgt tttcttttat cgacaggctt gggaaaagca gcggttcctg
    23641 gggaacgaga taaatgccca gctgatgagc atgaactggc gttaatctgg cgtagttgtt
    23701 gcccccaatc tccagcgtac cgctatcagc aggggtaata ccggcaataa tcttcattaa
    23761 cgtcgattta ccggcaccat tgccgccgag cagggcgtgg acctccccct gatgcaacgt
    23821 aaaatcgatg cctttcagga cattgacccc tgaatactgt ttataaaccg agcgggcgca
    23881 aagtagcggt aacgcgcggg tatcactcgt ttgcatattt cccccgttca gttttgcagg
    23941 tgagttttga acaaatgtat ttctgctttt aatttgttca taaccttagg tggacattgc
    24001 acatatttcc gacgaataga tcacaattta tgctattttg attttcacgg ttgcgtttgt
    24061 tcatgctcgt agagtcaaac tgtggctgcc atcacagata taaatgcgca agaactgaac
    24121 aattgcatta aagatttaaa tatgttcaaa gtgaagaatg aattatgaca atcaacgatt
    24181 cggcaatttc agaacaggga atgtgtgaag aagaacaggt cgcgcggatc gcgtggtttt
    24241 actatcacga cgggctgacc cagagcgaga tcagcgatcg tctcggcctg acccgtttga
    24301 aagtgtcgcg cttgctggag aaagggcatc agtccggcat tattcgcgta cagattaatt
    24361 ctcgctttga aggctgtctg gaatatgaaa ctcaattacg tcgtcagttt tcgctgcaac
    24421 atgtccgggt gatccctggg cttgcggatg ctgatgtcgg cgggcgactg gggataggcg
    24481 cggcgcatat gttgatgagt ttacttcaac cacaacagat gctggcgatt ggttttggcg
    24541 aggcaaccat gaatacgctg caacgcttaa gtggttttat ttcgtcacag caaattcgcc
    24601 tggtcacgct ctccggtggc gtcggttctt atatgacggg tatcgggcag cttaacgcgg
    24661 cgtgcagtgt gaatattatt ccggctccgt tgcgggcatc ctccgctgac attgcccgta
    24721 cgctaaaaaa tgaaaattgc gtcaaagatg ttctgttagc cgcgcaagca gccgatgtgg
    24781 cgattgtcgg cattggggcc gtcagtcaac aggacgacgc gacgatcatt cgctccggtt
    24841 atatcagcca gggcgaacag ttaatgattg gtcgaaaagg ggcggttggc gacattttag
    24901 gctacttttt tgatgcaaaa ggtgacgttg tcacggatat taaaatacat aacgaactga
    24961 ttggcttacc tttaagctcg ctgaagacca tacccgtccg ggttggcgtg gcagggggag
    25021 aaaataaagc cgaagcaatt gccgctgcaa tgaaaggcgg ttatatcaac gcactggtta
    25081 ccgatcagga cacagcagcg gcgattttac gtagttaaat ttgcatgacc ttattaccgg
    25141 gaatgatgga gaacgtatag aggaacagac agaacgcata agccgaggat aatctaatgg
    25201 ctcgactctt taccccttca gaatcaaagt attacctgat ggcgctggat gcaggtaccg
    25261 gaagtattcg ggctgtgata ttcgacctgg aaggcaatca aatagcagtg ggacaggcgg
    25321 agtggcggca cctggcagta ccggacgttc ctggttctat ggaatttgat ctcaacaaaa
    25381 actggcaact ggcgtgtgag tgtatgcgcc aggcgctgca caacgccggc atagccccgg
    25441 agtatatcgc tgccgtttcg gcatgttcga tgcgtgaagg cattgtttta tataataatg
    25501 aaggagcccc gatctgggcc tgcgccaatg tggatgccag agcggcacgc gaagttagcg
    25561 aacttaaaga actgcacaac aatacctttg aaaacgaagt ttatcgcgcg accggacaaa
    25621 cactggcttt aagtgccatc cccagattac tttggctggc gcaccatcgt tccgatattt
    25681 accgtcaggc atcaaccatc accatgatca gcgactggct ggcctatatg ctcagcggcg
    25741 aactggcggt ggatccctct aacgctggca ccacgggact tcttgatcta accacccgtg
    25801 actggaaacc tgcattgctg gatatggctg gcctacgtgc cgatattctt tctcctgtca
    25861 aagaaaccgg cacattgctg ggcgtggtaa gttcacaagc ggcggaactc tgcggtctga
    25921 aggcgggcac tccggtggtc gttggaggag gcgacgtgca gcttggttgc cttgggttag
    25981 gcgttgtgcg tccggcacaa accgcggttc ttggcggcac attctggcag caagttgtaa
    26041 atttagccgc gccggtgaca gacccagaaa tgaacgtgcg cgttaatcct catgttattc
    26101 ctggcatggt acaagctgaa tctataagct tttttaccgg actcaccatg cgctggttcc
    26161 gcgatgcttt ctgtgccgaa gaaaaactga ttgccgaacg tttaggcatc gacacctata
    26221 cgctgctgga agagatggcc agtcgggtgc cgcctgggtc gtggggcgta atgccgatct
    26281 tctccgacag aatgcgcttt aaaacctggt atcacgctgc gccttccttt attaacttgt
    26341 ccattgaccc ggataaatgt aacaaagcga cattgttccg tgcgctggaa gaaaatgcgg
    26401 cgattgtatc agcgtgtaac ttgcagcaaa ttgctgattt ctcgaatatt catccttcat
    26461 cgttagtctt tgcaggcgga ggttcaaaag ggaaattatg gagtcaaatt ctcgctgatg
    26521 tctcgggatt acccgtcaat attccggtgg tcaaagaagc cactgcatta ggatgtgcca
    26581 ttgcagctgg cgtcggtgcc ggaatttttt catcaatggc agaaaccgga gaacgcctgg
    26641 ttcgctggga acggacgcac acaccagacc cggaaaagca tgaactttat caggattcac
    26701 gcgataagtg gcaggcagtt tatcaggatc agctggggct ggttgatcat ggactgacga
    26761 cgtcgttatg gaaagcgcct gggttatagt ttcattgaca gccacatcat gatgaccgtg
    26821 gctgttagtt tttgagtata gttattctta tttcccttct tttagagctg gcttgttaaa
    26881 agccagcttg cagattcatc gttccatcac cagtactata ttcaagggaa aattgctatt
    26941 tttcttaaag cattaagcac aacccttatt ttatagcgaa tattcctaaa gacactaatg
    27001 gatgcaaaag gggtttaata aacttcgatt tttagcaatt agtgctattc tttgttaaat
    27061 atgatgatga taattttcct attgaaagaa acagttttct tattaagcaa caataactca
    27121 tagttcatgt ttaaataaaa taagaactat gcaattttta atctatcaat tcgaaagcat
    27181 tagcaaatta gccaaattga caccttccca cctccaacta acactcaata cagacctctg
    27241 acaatttaat aagtttcatt tttaatgtct gacgactcat ctctttcgtg gctgtattgt
    27301 ttgtatatgg agcgtttata tgaatagaat ctatcgcgtg atatggaatt gcactctaca
    27361 ggtatttcag gcctgctcgg aattaactcg cagggcaggt aaaacatcga cggttaattt
    27421 gcgtaaatcc tctggactga caacgaaatt cagtagattg acgctgggtg ttttgctggc
    27481 actaagcggt tcagcgtctg gtgcaagtct ggaagttgat aatgatcaga ttaccaatat
    27541 tgatactgat gttgcttatg atgcctacct ggttggctgg tatggcactg gagtgcttaa
    27601 tattttggct ggcggtaatg cctccttaac cactattact accagcgtca ttggcgctaa
    27661 tgaggactca gagggcaccg ttaatgtttt gggtggcacc tggcgattgt atgatagcgg
    27721 aaataatgca aggcctttaa atgtgggtca atccggaacg gggacgctga atattaaaca
    27781 gaagggtcac gtcgatggag gctatttaag attaggttct tcgacaggag gcgtcgggac
    27841 ggtcaatgtt gagggagagg actctgttct gacgaccgaa ttattcgaaa tagggagtta
    27901 cggtacgggc tcattaaata ttacggataa gggttacgtc acgagttcaa tcgtcgccat
    27961 tttaggctat caggcgggca gtaatggcca ggttgtcgtt gaaaagggtg gcgagtggct
    28021 aataaaaaat aacgattcct caattgaatt tcaaattggt aatcaaggaa cgggggaagc
    28081 gactattcgc gagggtggac tgattacggc tgaaaacacg attatcggtg gcaatgctac
    28141 cggtatcgga accctgaatg tgcaggatca agactctgtc atcacggtac gcagactcta
    28201 taatggatat ttcggtaatg gcacactcaa tatttccaat aatggactaa ttaataacaa
    28261 agaatattca ttagtgggcg ttcaggacgg ttcccacggt gtcgtcaacg tgaccgataa
    28321 agggcattgg aatttcctcg gaacgggcga agctttccgc tatatctata tcggtgatgc
    28381 tggcgacggt gaacttaatg tctcgcgtga aggtaaagta gattcgggaa ttatcactgc
    28441 ggggatgaaa gaaacaggca caggcaacat tactgttaag gataagaact ccgttatcac
    28501 taatctcgga actaatcttg gttatgacgg ccacggcgaa atggatatca gtaatgaggg
    28561 gcttgttgtc agcaacggag gaagctcact cggttatgga gaaaccggcg tcgggaatgt
    28621 cagcatcacc acggggggga tgtgggaggt caataagaat gtctatacca ccattggtgt
    28681 tgcgggcgtc ggaaacctca atattagcga tggcggtaag ttcgtatcgc aaaatattac
    28741 ttttttgggc gataaagcaa gcggtatcgg cacactgaac ctgatggatg cgacatcatc
    28801 gttcgatact gtgggtatca atgtcggtaa ttttggtagc ggtatcgtaa atgtcagtaa
    28861 tggtgccacc cttaattcaa cgggctatgg atttatcgga ggaaatgcct ccggtaaggg
    28921 gatagttaat atttcaacgg acagtctctg gaatttaaag acatcatcta ctaacgcaca
    28981 attgctacag gtcggtgtat taggcaaggg tgaactgaat attaccaccg gaggtatagt
    29041 taaagcgcgt gatacacaga tagctctcaa tgacaaaagt aagggcgacg tgagggtgga
    29101 tgggcagaac tctcttcttg aaacattcaa tatgtacgta gggacatctg gtacgggtac
    29161 gttaaccctg acgaatagcg gcacgctgaa tgtcgaaggt ggagaagttt acttaggtgt
    29221 ttttgaacct gctgtaggaa cgctaaacat tggtgcagct cacggtgagg cggcggcaga
    29281 tgccgggtat ataaccaacg cgacgaaagt agagtttggt tctggcgaag gtgtttttgt
    29341 ctttaatcat actaataaca gtgatgccgg ctaccaggtc gatatgctga ttacaggtga
    29401 cgataaagac ggaaaagtga tccatgatgc aggccatacg gtgttcaatg cagggaatac
    29461 ttatagcggt aaaacgctgg tcaatgacgg cctcctgacc attgcgtctc atacggcaga
    29521 tggggtaacg ggcatgggtt cgagtgaagt caccattgca agccccggta cgctcgacat
    29581 tctcgcatca acgaacagtg caggagatta cacgctgacc aatgcgctca aaggcgatgg
    29641 cttgatgcga gtgcagctgt catcctacga caagatgttt ggctttaccc atgcaacagg
    29701 gactgaattc gccggtgttg cccaactgaa agacagtacc ttcactctgg aacgcgacaa
    29761 caccgctgcg cttactcacg cgatgttgca gtctgacagt gaaaatacca catcggtaaa
    29821 agtgggagag caatccattg gtggactggc tatgaatggc ggtacgctca ttttcgatac
    29881 ggatattcct gctgcgacgc ttgcagaggg atatatcagc gtcgatacgc tggttgtcgg
    29941 cgcgggtgac tacacctgga aaggccgtaa ctatcaggta aacgggacgg gcgacgtgct
    30001 tatcgacgtg cctaaaccgt ggaatgatcc catggcgaat aaccctctga cgacgctcaa
    30061 tttgctggaa cacgacgata gccatgtcgg cgttcaactg gtgaaggcgc aaacggttat
    30121 tgggtcgggt ggctcattaa cgttacgtga tttacagggc gacgaggtgg aagcggacaa
    30181 aacgttacac attgcgcaaa acggaacggt ggtcgccgag ggtgattatg gattccgcct
    30241 cacgaccgca ccaggtgatg gtttgtacgt taactatggg ctgaaagcgc tgaacatcca
    30301 tggtgggcaa aagctgacgt tagccgaaca tggcggagcc tatggcgcaa cggccgatat
    30361 gtcggcaaaa atcggtggtg aaggggatct ggcaatcaat acggtgcgac aggtttcgct
    30421 ttccaacggt cagaacgact atcagggggc aacctacgtt cagatgggga cattacgtac
    30481 cgatgcggat ggtgcacttg gcaacacccg ggaactgaac atcagcaacg cggccatcgt
    30541 cgatcttaat ggatcgacgc agacggtaga gacattcacc gggcagatgg gttcgactgt
    30601 tttgttcaaa gagggggcgc tgacggtaaa taaaggtggg atcagtcagg gtgaactgac
    30661 aggtggcgga aacctgaatg ttacaggggg aacgctggct atcgaggggc ttaatgcacg
    30721 ctacaatgcg ttaaccagca ttagcccaaa tgcggaagtc agcctcgata atactcaggg
    30781 gttaggcaga ggaaatattg ccaatgacgg tctgttaacg ctaaaaaacg tgactggcga
    30841 actgcgtaat agcataagcg ggaagggtat cgtgagcgca accgccagga cagatgtaga
    30901 gctggatggc gataatagcc gctttgtggg gcaattcaac attgatacag gcagcgcgct
    30961 cagcgtcaac gagcagaaaa acctgggtga tgcttccgtt atcaataatg gcctgctcac
    31021 catctccact gagcgtagct gggcgatgac gcacagtatc agcggtagcg gtgatatgac
    31081 aaaactgggt accgggatcc tgactcttaa caacgattcc gcggcgtatc agggtacgac
    31141 ggatatcgtg gggggggaaa ttgctttcgg ttccgactct gccattaata tggcaagtca
    31201 acacattaat atccataaca gcggtgtgat gtcgggaaat gtcaccactg caggtgatgt
    31261 gaacgttatg cctgggggga cactgcgtgt cgctaaaacc acaatcggcg gcaacctgga
    31321 gaatggcggc acggttcaaa tgaatagcga aggggggaaa ccggggaatg tactgaccgt
    31381 taacggcaac tataccggaa acaatggcct gatgacgttc aacgcgacgc tgggcggcga
    31441 taattcgccc accgataaaa tgaacgtgaa aggcgatacc caagggaaca ctcgcgttcg
    31501 ggttgataac attggcggcg tcggtgcaca aacggtcaac ggtattgaac tcattgaggt
    31561 tggcggtaat tctgcaggta acttcgcgct gaccaccgga actgtcgaag ctggggctta
    31621 cgtctacacg ctggctaaag ggaaggggaa tgacgagaaa aactggtatc tgaccagtaa
    31681 atgggacggc gtaacgccag cggatacgcc cgaccccatc aataatcccc ctgttgtgga
    31741 tccggaaggc ccatcagttt atcgcccgga ggccggaagc tatatcagca acattgccgc
    31801 agccaactcg ctgtttagcc atcgtttaca cgaccgtctg ggtgagccgc agtatataga
    31861 ttcactgcat tctcaggggt cggcaagcag tatgtggatg cgtcatgtcg gagggcacga
    31921 acgttcaagg gccggtgacg gtcagctaaa tactcaggct aaccgctatg tattgcagct
    31981 aggcggcgat ttggcgcagt ggagtagcaa cgcgcaggat cgctggcatc ttggcgtgat
    32041 ggcaggttac gctaatcagc acagtaatac tcagagtaat cgtgtgggtt ataaatcgga
    32101 tgggcgcatc agcggttaca gcgctgggct gtacgcgacc tggtatcaga acgatgcgaa
    32161 taagaccggc gcttatgttg acagctgggc gctgtataac tggtttgata acagcgtcag
    32221 ttccgataac cgttctgctg acgactatga ttctcgcggt gtgacggcct ctgttgaggg
    32281 tgggtatacc tttgaagcgg gaacatttag cggcagcgaa gggacgctga atacctggta
    32341 cgtccagcca caggcgcaaa tcacctggat gggtgtgaaa gattccgacc atacccggaa
    32401 agacggaacg cgcattgaaa cggaaggcga cggaaatgtg caaacgcgac ttggggtgaa
    32461 aacctacctg aacagccatc accagcgtga cgatggtaaa cagcgtgagt tccagcctta
    32521 cattgaagcg aattggatca acaacagcaa agtctacgcc gtgaagatga atggtcaaac
    32581 cgtaggccat gaaggtgcgc gtaatctcgg tgaagtacgt accggggttg aggcgaaagt
    32641 aaataacaac cttagcctgt gggggaatgt cggtgtgcaa ctaggtgata aaggctatag
    32701 cgatactcag ggcatgctgg gagtgaaata tagctggtaa accgtataag ccgcatgtcg
    32761 agatggcatg cggcttaata ttgccgactt caaaggcttt aaagcctccc ttttatccgc
    32821 gatcgcggat atcgcagcgt ttatcccgta cagcggataa gatgtgtttc cagattgact
    32881 ttatcctcac taaaggataa aactgataat atccccttaa gcggataaat ttgctgtgga
    32941 cgtatgacat gatgagcttt cagaagatct atagcccaac gcaattagcg aatgcaatga
    33001 aactggttcg ccagcaaaat ggctggacgc agagcgagct ggcgaaaaaa attggcatta
    33061 agcaggcgac aatttccaat ttcgaaaaca accctgacaa taccacgctc acgacatttt
    33121 ttaagatttt acagtcgctt gaactctcaa tgacactatg cgacacgaaa aatgcctcgc
    33181 cagaatcaac agaacagcaa gatctggagt ggtaatgcct aaacttgtca cttggatgaa
    33241 caaccagcgg gtaggcgagt taacgaagtt agccaacggc gcgcacacct ttaagtatgc
    33301 accggagtgg ttagccagcc gttatgccag accgttgtca ctttcgctgc cattgcagag
    33361 ggggaatatc acctcagatg ccgtatttaa cttcttcgat aacctgttac ccgatagccc
    33421 gattgtacgt gaccggatcg ttaaacgtta tcatgctaaa tccagacaac cgtttgattt
    33481 attgtcagaa atagggcgag acagcgttgg tgccgtaacg ttattacccg aaaatgaaac
    33541 cataacgcgc ccgataatgg catgggaaaa gcttactgaa gccaggcttg aagaagtatt
    33601 aacggcttat aaagcagata tccctctggg catgattaga gaagaaaatg actttcgcat
    33661 ctcggttgct ggcgcgcagg agaagacagc gctgcttaga ataggcaatg actggtgcat
    33721 tccgaaagga ataacgccga cgacgcacat cattaaatta ccgattggcg aaatcaggca
    33781 gcccaatgcg acgctcgatc tcagccaaag cgttgataat gagtattact gtctgctgct
    33841 ggcgaaagaa cttgggttga atgttccgga tgcagaaatc attaaagcgg gaaatgtgcg
    33901 cgcgttagcg gtcgaacgtt ttgacaggcg ttggaatgct gagcgaacgg ttttacttcg
    33961 cttgccacag gaggatatgt gtcagacatt cggtttacct tcatcggtga aatatgaatc
    34021 agatggaggc ccaggcatcg cgcggatcat ggcttttttg atggggtcca gcgaggcgct
    34081 gaaagatcgc tatgatttta tgaaattcca ggtcttccag tggttgattg gcgcaacgga
    34141 cggtcatgca aaaaacttct ccgtatttat tcaggctggc ggcagttatc gactcacgcc
    34201 attttacgac atcatttcag catttccggt ccttggcggt acgggaatac acatcagcga
    34261 tctcaaactg gcaatggggc ttaacgcatc caaaggcaaa aaaacggcaa tcgataaaat
    34321 ttatccgcga cattttttgg cgacagcaaa ggtgctgaga ttcccggaag tgcagatgca
    34381 tgaaatccta agtgactttg ccagaatgat tccggcagca ctggataacg tgaagacttc
    34441 attaccgaca gattttccgg agaacgtggt gacggcagtt gaaaccaatg tgttgaggtt
    34501 gcatggacgg ttaagccgag aatacggtag taagtgagat atggggtttg gtcgttgtta
    34561 atgagcacga caatcatgac cgccaacgac tggattcttc cttggtttat gctggtgcgc
    34621 ataatgtata ttatgttaaa tcatgtctga gtgatgcgaa gtgcttttct ggtagtcgtt
    34681 attcgttcag ggttcaagaa cttaagcctc tcctctttca taattggcct gtgcatggag
    34741 aaatagcctg gttattccct gccccatgct aagagcgcag tgtctgtcgc atagacactg
    34801 catacgaaaa caccagaggg tgctgttact tatttaagga cggatcaagc gggaatgagt
    34861 ccactccggt atcagaaatg gctacgtctc aatgaagtca ggcgaccgat gctgaatgaa
    34921 cattacgatg tcaccacagc agcctatgct gtcggttacg aaagctatcc catttcagtc
    34981 gggaatattc gcggatgttt ggagagtcac ccaagagaga tattaccagg ttaagaaagt
    35041 ctgtcggtca gctttaataa accctgcact tatctgttta gagcaattcg gtgttagttt
    35101 cagcaagcaa acattaacca tagctaatga tttatagcca tattaaccat tagtagccct
    35161 tgacctttcc tgacacttcc cttgttcgca ataatattct gtttagtcac ggtttataaa
    35221 taacatgcat aatgaaatcg tcatgttatt tagcgacata aaatgttttt gcaaatactc
    35281 tcttcaacaa gtgcagcaat aaacttgttg tgattaggtg tccttgtgat ttaaagatat
    35341 tatcgttctt cgtgaaatgt aataaccctg gaaactatat tctcagggca acaaccaatc
    35401 aagaatgatt cttgttttat aagcaataac agaatgactt aattgttaac tctctttatt
    35461 cagctactta aatataaatt ttggagaatt atgaaactca aacatgttgg tatgattgtc
    35521 gtttctgtgt tggcgatgtc gtctgctgcg gtaagcgcag ccgagggtga tgaatcagta
    35581 acgaccactg ttaatggcgg tgttattcat tttaaaggtg aagtggtaaa tgccgcttgt
    35641 gcaattgatt cagaatcaat gaaccaaacg gttgagctgg gtcaggttcg ttcttctcgc
    35701 ctggctaaag cgggtgacct cagctccgcc gttggcttca atatcaagct gaatgattgt
    35761 gataccaatg tttccagtaa tgcagctgtt gcattcctgg gtactactgt caccaggaat
    35821 gacgatacgt tagcgctgca gagttcagcg gcaggctctg cccaaaatgt cggtattcaa
    35881 attttggacc gtacgggtga ggtattaata cttgatgggg ccacttttag tgctaaaacc
    35941 gacttgattg atggcacgaa tatactgcca ttccaggctc gttatattgc tctcgggcag
    36001 tccgtagctg gtactgcaaa cgctgatgcg accttcaaag ttcaatatct ataattcaat
    36061 cttaaggtgg ctatacgtca tctgaaattg aaacagggtg tgtgtggcat ggctacgcac
    36121 acccgagcaa tttaccaata ttcatctcat ttttaatgag aaatggtttg tatttggagc
    36181 gctatgaaaa atcacataat atctaaacta tcaataaaca acagtagtta aacttactgt
    36241 tatttaaaat atttactttg tagcaaggtt ttcctattaa aagagaacca acatttatta
    36301 caaacgcatt aagtctggaa acccggcgac tcgccaatgt attagcaaca ttaatcgatt
    36361 gtctgatgta acggttttcc cgcttatcct cttaacacat ggagaatgca tcagatgcaa
    36421 actacgcgta ccccctactc tatttccttt atggcgacag tgttactttt attgctcttt
    36481 gcttgccata gcaccgttgc caacgcagct gtcgcactgg gtgcgacgcg ggtaatttat
    36541 ccggcaaacc agaaacaggt tttattgcct gtcacgaata atgatcctgc cagtgtctat
    36601 ctcattcagt catggataga aaatgcaggt gaccaaaaag acacccagtt tgtcattacc
    36661 ccaccgcttt tttccatgca aggtaaaaaa gagaatacgc tgcggataat caacgctact
    36721 aatcatcagt taccaggcga ccgtgaaagc ctgttctggg tgaatgttaa agctattcct
    36781 gctatggaaa aagaccagaa gaatgagaat acattacagc tggcaattat tagccgcata
    36841 aaaatgtttt atcgccccac gaacctggca atggcacctg aagaagcgcc tgcaatgctt
    36901 cggtttcgtc gcagcggtag caaactcacg cttattaatc caacgcccta tttcattacc
    36961 gtaacaaata tgaaagcagg aaatagcaat ctcccaaaca ccatggtgcc gccaaaaggt
    37021 gaagtatcgg tggatatcac gcatgctgca accggggata tcagttttca gacgatcaat
    37081 gattacggtg cattaactcc gcgtattaag gcaaccatgc agtaagccag tgacctaatt
    37141 aataataaac tcaatcggaa ttaataatga cagccattcg tgccgcattt aaggcatatc
    37201 gtatgcatca ggtgttaata atgcctcgct ttgcacggct taccattgcc cttggcttag
    37261 caactgcggt atttcccgtt gacgcagagt attattttaa tccacggttt ttaagcaatg
    37321 atcttgctga atctgtcgat ttatccgcct ttactaaggg acgcgaggca ccacctggta
    37381 catatcgggt cgacatttat ttgaacgatg aatttatgac tagtcgggat attactttta
    37441 ttgcagatga taataatgca gaactcatcc catgcctgag tacagatctt cttgtcagtc
    37501 ttggtataaa aaaatcagcg ttattagaca ataaagaaca ttcggcagaa aaacatgtgc
    37561 cggacaacag cgcatgcaca ccacttcagg atcgtttggc cgacgcatca actgagtttg
    37621 atgttggtca gcaacatttg tcactctccg ttccgcaaat ttatgttggc agaatggctc
    37681 gcggctatgt ttctcctgat ctgtgggaag aaggaataaa tgctgggctt ctaaactata
    37741 gttttaatgg taattctatt aataatcgta gtaaccataa tgcaggaaaa tcaaactatg
    37801 catatttgaa tttacagagt ggcatcaaca ttggtagttg gcgactgcgc gataactcaa
    37861 cgtggagtta ttacagtggg agtagcaatt catctgacag caataaatgg cagcatatca
    37921 atacgtcggc tgaacgtgac attattccct tacgctcacg gttaacggta ggtgatagtt
    37981 ataccgatgg cgatattttt gatagtgtga actttcgtgg cctcaaaata aattcaacag
    38041 aagcgatgtt gcccgatagc caacatggtt tcgctccggt gattcatggt attgcccgtg
    38101 gaaccgcaca agtgagtgta aaacagaacg gatacgatgt ttatcagact actgttccac
    38161 ccggcccttt tactattgat gatatcaact ctgcggccaa tggtggtgat ctgcaagtaa
    38221 ccataaaaga ggcagacggc agtattcaga cattatatgt tccttattcg tctgttccgg
    38281 ttctccaacg tgctggatat acgcgttatg cgcttgccat gggggaatat cgtagtggaa
    38341 ataacctgca aagctctccc aagttcatac aaggtagctt gatgcatggt ctggaaggaa
    38401 actggacacc ttatggcgga atgcaaattg cagaagatta tcaggccttc aaccttggta
    38461 ttgggaaaga tttaggactt tttggtgcct tttctttcga tatcacgcag gccaatacga
    38521 cacttgcaga tggcacccgt cacagtgggc aatcggttaa atccgtctac agcaaatcct
    38581 tctaccagac aggaaccaat atccaggtcg caggatatcg ctattctacg caaggttttt
    38641 ataacttatc cgacagtgcc tacagtcgaa tgagtggtta caccgtcaag cctcctaccg
    38701 gagacaccaa tgagcagaca caatttattg attattttaa tctgttctac agtaagcgtg
    38761 gtcaggaaca aataagcatc tctcagcagc ttggaaatta cggtacgaca tttttcagtg
    38821 ccagtcgcca aagttactgg aacacgtcac gcagcgacca gcaaatatca tttggattaa
    38881 atgtgccgtt tggtgatatt acgacttcgc tgaattacag ctattccaat aatatatggc
    38941 aaaacgatcg ggatcattta ctcgctttta cgcttaatgt tcccttcagt cattggatgc
    39001 gtacagacag tcagtcggca tttcgtaatt caaacgccag ttacagtatg tcaaacgatt
    39061 tgaaaggcgg catgaccaat ctatcggggg tttatggcac tctgctgccg gataataacc
    39121 tgaattatag cgttcaggtc ggtaacaccc acggaggtaa tacatcgtct ggcaccagtg
    39181 gttacagttc tcttaattat cgtggagctt acggtaatac gaatgtcggt tacagtcgga
    39241 atggtgacag cagccagatt tattacggaa tgagtggtgg gattattgct catgctgatg
    39301 gcatcacctt tggacagccg ctgggcgaca caatggttct ggttaaggct cctggcgctg
    39361 ataatgtcaa aatagagaac cagaccggaa ttcataccga ctggcgtggc tatgcaatat
    39421 taccatttgc gacagaatat agagaaaatc gtgtcgctct taacgcgaat tcccttgcag
    39481 ataatgttga actggatgaa accgtagtca ctgtcatccc aactcacggt gctattgcca
    39541 gagcaacatt taatgcacaa atcggcggga aagtattaat gacgttgaag tacggtaata
    39601 aaagcgttcc attcggtgca attgtcactc acggagagaa taaaaatggc agcattgtcg
    39661 cggaaaatgg tcaggtttat ctgactggac ttccacagtc agggaaatta caggtttcat
    39721 ggggcaatga taaaaactca aactgtattg tcgattacaa gcttcctgaa gtctctcctg
    39781 gaaccttgct gaaccagcag acagcaatct gtcgctaagg aacaatagat tatgaaatac
    39841 aataacgtta ttttcctcgg tttatgtctg gggttaacca cctattctgc tttatccgca
    39901 gatagcgtta ttaaaattag cgggcgcgtc ctcgattatg gctgcacagt ctcatcggat
    39961 tcgcttaatt ttaccgtaga tctccaaaaa aacagtgcca gacaatttcc aacgaccggt
    40021 agcacaagtc cagccgtccc ttttcagatt acgttaagtg aatgcagcaa agggacaacg
    40081 ggggttcggg ttgcatttaa cggtattgag gatgcagaaa ataatactct gttgaaactg
    40141 gatgagggaa gcaatacggc ctccggttta ggtatagaaa tactggacgg aaatatgcgt
    40201 ccggtgaaac tgaatgacct tcatgccggg atgcagtgga tcccactggt accagaacag
    40261 aacaatattt tgccttactc cgctcgtctg aagtcaactc agaagtccgt caatccggga
    40321 ctggtgaggg cttcggcaac ctttaccctt gaatttcaat aatcagagtc agatatgaaa
    40381 agacttcaca agaggttcct gttagctacg ttttgcgcgt tattcacagc aactctccag
    40441 gccgtcgatg tcactatcac tgttaatggt cgggtagtcg ctaaaccctg cactattcaa
    40501 accaaagaag ctaacgttaa tctcggggat ctttatacgc gcaatctgca acaacctggt
    40561 tctgcatctg gctggcacaa tattactttg tcattaaccg attgtccggt tgaaacaagt
    40621 gcagtgacgg caatcgtgac aggttcaact gacaatacgg gttattacaa aaatgaaggt
    40681 actgccgaaa atattcagat agagctgagg gatgaccagg atgcgacgtt aaaaaatggc
    40741 gatagcaaaa cggttattgt tgatgagatc actcgtaatg cacagtttcc acttaaggca
    40801 agagctatca cggtgaatgg aaacgcaagc cagggaacga tcgaggcgct aatcaatgtg
    40861 atctacacct ggcaataacg tcgattcgat tttcttagcc ttctttttaa atcaattttt
    40921 aaccttagga tatatcatgg gtaaaacaat cagtataaag gtcctgttcg gtatttatct
    40981 tctattaatg gcaggcaaag tttttgcctt cagttgtaat gtcgatggcg ggtcaagtat
    41041 tggagcaggt acaacctctg tttatgttaa tctcgaccct gtaatacagc cgggccagaa
    41101 tctggttgta gacttgtctc agcatataag ttgctggaat gattacggcg gctggtacga
    41161 cactgatcat ataaacctgg tacaaggctc agctttcgca ggctccctac agtcatataa
    41221 aggatcgctg tactggaata atgtgaccta ccccttcccg ttgacgacaa ataccaacgt
    41281 attggatatt ggtgataaga caccgatgcc attaccgtta aaactctata ttaccccagt
    41341 tggggcggcc ggtggagttg tcataaaagc gggggaagtc attgcccgta ttcatatgta
    41401 taaaattgca acattaggaa gcggaaatcc gcgtaatttt acgtggaata ttatttcaaa
    41461 taacaatgtt gttatgccaa caggcggctg caccgttgat agtcgtaatg tcaccgtgga
    41521 tctcccggac tttcctggaa gcgcagaaat accccttggc gtatattgct caagcgaaca
    41581 aaagctctca ttttatcttt cgggtgccac cactgacagt gcccgacaag tgtttgctaa
    41641 cacagcacca gatgcaacaa aagcatcggg agtgggtgtc tctctgatgc gtaatggaaa
    41701 aatactggct acgggagaaa atgtctcctt ggggacagta aataaaagca aagtacctct
    41761 gggtttaagc gcaacctatg gacaaacagg gaacaaagtt tcagccggaa ccgtccagtc
    41821 agtcattggt gtcactttta tctatgaata attgtgattt tgaccttagt ctatgcgctc
    41881 cattcacgaa aattgcgcgg ataattattt tgtgaaagct attatcctac acctgtaaga
    41941 aaa
//
LOCUS       DAPGUL010000030        41587 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.030, whole genome shotgun sequence.
ACCESSION   DAPGUL010000030 DAPGUL010000000
VERSION     DAPGUL010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 41587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41587
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.030"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            321..1889
                     /gene="cydA"
                     /locus_tag="RHX21_001754"
     CDS             321..1889
                     /gene="cydA"
                     /locus_tag="RHX21_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415261.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="HDV1986952.1"
                     /translation="MLDIVELSRLQFALTAMYHFLFVPLTLGMAFLLAIMETVYVLSG
                     KQIYKDMTKFWGKLFGINFALGVATGLTMEFQFGTNWSYYSHYVGDIFGAPLAIEGLM
                     AFFLESTFVGLFFFGWDRLGKVQHMCVTWLVALGSNLSALWILVANGWMQNPIASDFN
                     FETMRMEMVSFSELVLNPVAQVKFVHTVASGYVTGAMFILGISAWYMLKGRDFAFAKR
                     SFAIAASFGMAAVLSVIVLGDESGYEMGDVQKTKLAAIEAEWETQPAPAAFTLFGIPD
                     QEEETNKFAIQIPYALGIIATRSVDTPVIGLKELMVQHEERIRNGMKAYSLLEQLRSG
                     STDQAVRDQFNSMKKDLGYGLLLKRYTPNVADATEAQIQQATKDSIPRVAPLYFAFRI
                     MVACGFLLLAIIALSFWSVIRNRIGEKKWLLRAALYGIPLPWIAVEAGWFVAEYGRQP
                     WAIGEVLPTAVANSSLTAGDLIFSMVLICGLYTLFLVAELFLMFKFARLGPSSLKTGR
                     YHFEQSSTTTQPAR"
     gene            1905..3044
                     /gene="cydB"
                     /locus_tag="RHX21_001755"
     CDS             1905..3044
                     /gene="cydB"
                     /locus_tag="RHX21_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HDV1986953.1"
                     /translation="MIDYEVLRFIWWLLVGVLLIGFAVTDGFDMGVGMLTRFLGRNDT
                     ERRIMINSIAPHWDGNQVWLITAGGALFAAWPMVYAAAFSGFYVAMILVLASLFFRPV
                     GFDYRSKIEETRWRNMWDWGIFIGSFVPPLVIGVAFGNLLQGVPFNVDEYLRLYYTGN
                     FFQLLNPFGLLAGVVSVGMIITQGATYLQMRTVGELHLRTRATAQVAALVTLVCFALA
                     GVWVMYGIDGYVVKSTMDHYAASNPLNKEVVREAGAWLVNFNNTPILWAIPALGVVLP
                     LLTILTARMDKAAWAFVFSSLTLACIILTAGIAMFPFVMPSSTMMNASLTMWDATSSQ
                     LTLNVMTWVAVVLVPIILLYTAWCYWKMFGRITKEDIERNTHSLY"
     gene            3059..3172
                     /gene="cydX"
                     /locus_tag="RHX21_001756"
     CDS             3059..3172
                     /gene="cydX"
                     /locus_tag="RHX21_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-I oxidase subunit CydX"
                     /protein_id="HDV1986954.1"
                     /translation="MWYFAWILGTLLACSFGVITALALEHVESGKAGQEDI"
     gene            3172..3465
                     /gene="ybgE"
                     /locus_tag="RHX21_001757"
     CDS             3172..3465
                     /gene="ybgE"
                     /locus_tag="RHX21_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyd operon protein YbgE"
                     /protein_id="HDV1986955.1"
                     /translation="MSKIIATLYAVMDKRPLRALSFVMALLLAGCMFWDPSRFAAKTS
                     ELEIWHGLLLMWAVCAGVIHGVGFRPQKVLWQGIFCPLLADIVLIVGLIFFFF"
     gene            3615..4019
                     /gene="ybgC"
                     /locus_tag="RHX21_001758"
     CDS             3615..4019
                     /gene="ybgC"
                     /locus_tag="RHX21_001758"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system-associated acyl-CoA thioesterase"
                     /protein_id="HDV1986956.1"
                     /translation="MNTTLFRWPVRVYYEDTDAGGVVYHASYVAFYERARTEMLRHHH
                     FSQQALMAERVAFVVRKMTVEYYAPARLDDMLEIQTEITSMRGTSLVFTQRIVNAENT
                     LLNEAEVLVVCVDPLKMKPRALPKSIVAEFKQ"
     gene            4016..4708
                     /gene="tolQ"
                     /locus_tag="RHX21_001759"
     CDS             4016..4708
                     /gene="tolQ"
                     /locus_tag="RHX21_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tol-Pal system protein TolQ"
                     /protein_id="HDV1986957.1"
                     /translation="MTDMNILDLFLKASLLVKLIMLILIGFSIASWAIIIQRTRILNA
                     AAREAEAFEDKFWSGIELSRLYQESQGKRDNLTGSEQIFYSGFKEFVRLHRANSHAPE
                     AVVEGASRAMRISMNRELENLETHIPFLGTVGSISPYIGLFGTVWGIMHAFIALGAVK
                     QATLQMVAPGIAEALIATAIGLFAAIPAVMAYNRLNQRVNKLELNYDNFMEEFTAILH
                     RQAFTVSESNKG"
     gene            4712..5140
                     /gene="tolR"
                     /locus_tag="RHX21_001760"
     CDS             4712..5140
                     /gene="tolR"
                     /locus_tag="RHX21_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin uptake protein TolR"
                     /protein_id="HDV1986958.1"
                     /translation="MARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVE
                     VDLPDATESQAVSSNDNPPVIVEVSGIGQYTVVVEKDRLERLPPEQVVAEVSSRFKAN
                     PKTVFLIGGAKDVPYDEIIKALNLLHSAGVKSVGLMTQPI"
     gene            5205..6470
                     /gene="tolA"
                     /locus_tag="RHX21_001761"
     CDS             5205..6470
                     /gene="tolA"
                     /locus_tag="RHX21_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="HDV1986959.1"
                     /translation="MSKATEQNDKLKRAIIISAVLHVILFAALIWSSFDENIEASAGG
                     GGGSSIDAVMVDSGAVVEQYKRMQSQESSAKRSDEQRKMKEQQAAEELREKQAAEQER
                     LKQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAA
                     KKAAADAKKKAEAEAAKAAAEAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEK
                     AKAEAEKKAAAEKAAADKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAADKKAA
                     AAKAAAEKAAAAKAAAEADDIFGELSSGKNAPKTGGGAKGNNASPAGSGNTKNNGASG
                     ADINNYAGQIKSAIESKFYDASSYAGKTCTLRIKLAPDGMLLDIKPEGGDPALCQAAL
                     AAAKLAKIPKPPSQAVYEVFKNAPLDFKP"
     gene            6603..7895
                     /gene="tolB"
                     /locus_tag="RHX21_001762"
     CDS             6603..7895
                     /gene="tolB"
                     /locus_tag="RHX21_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001646851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tol-Pal system protein TolB"
                     /protein_id="HDV1986960.1"
                     /translation="MKQALRVAFGFLILWASVLHAEVRIVIDSGVDSGRPIGVVPFQW
                     AGPGAAPEDIGGIVAADLRNSGKFNPLDRARLPQQPGSAQEVQPAAWSALGIDAVVVG
                     QVTPNPDGSYNVAYQLVDTGGAPGTVLAQNSYKVNKQWLRYAGHTASDEVFEKLTGIK
                     GAFRTRIAYVVQTNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVT
                     FESGRSALVIQTLANGAVRQVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYVMDLA
                     SGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNINGGAPQRITWEGSQN
                     QDADVSSDGKFMVMVSSNGGQQHIAKQDLATGGVQVLSSTFLDETPSLAPNGTMVIYS
                     SSQGMGSVLNLVSTDGRFKARLPATDGQVKFPAWSPYL"
     gene            7930..8451
                     /gene="pal"
                     /locus_tag="RHX21_001763"
     CDS             7930..8451
                     /gene="pal"
                     /locus_tag="RHX21_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-associated lipoprotein Pal"
                     /protein_id="HDV1986961.1"
                     /translation="MQLNKVLKGLMIALPVMAIAACSSNKNASNDGSEGMLGAGTGMD
                     ANGGNGNMSSEEQARLQMQQLQQNNIVYFDLDKYDIRSDFAQMLDAHANFLRSNPSYK
                     VTVEGHADERGTPEYNISLGERRANAVKMYLQGKGVSADQISIVSYGKEKPAVLGHDE
                     AAYSKNRRAVLVY"
     gene            8461..9252
                     /gene="cpoB"
                     /locus_tag="RHX21_001764"
     CDS             8461..9252
                     /gene="cpoB"
                     /locus_tag="RHX21_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein CpoB"
                     /protein_id="HDV1986962.1"
                     /translation="MSSNFRHQLLSLSLLVGIAAPWAAFAQAPISSVGSGSVEDRVTQ
                     LERISNAHSQLLTQLQQQLSDNQSDIDSLRGQIQENQYQLNQVVERQKQILLQIDSLS
                     SGGAAAQSTSSDQSGAAASTTPTADAGTANAGAPVKSGDANTDYNAAIALVQDKSRQD
                     DAMVAFQNFIKNYPDSTYLPNANYWLGQLNYNKGKKDDAAYYFASVVKNYPKSPKAAD
                     AMFKVGVIMQDKGDTAKAKAVYQQVISKYPGTDGAKQAQKRLNAM"
     gene            9417..9492
                     /locus_tag="RHX21_001765"
     tRNA            9417..9492
                     /locus_tag="RHX21_001765"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9450..9452,aa:Lys,seq:ttt)
     gene            9628..9703
                     /locus_tag="RHX21_001766"
     tRNA            9628..9703
                     /locus_tag="RHX21_001766"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9661..9663,aa:Val,seq:tac)
     gene            9706..9781
                     /locus_tag="RHX21_001767"
     tRNA            9706..9781
                     /locus_tag="RHX21_001767"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9739..9741,aa:Lys,seq:ttt)
     gene            9932..10007
                     /locus_tag="RHX21_001768"
     tRNA            9932..10007
                     /locus_tag="RHX21_001768"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9965..9967,aa:Val,seq:tac)
     gene            10011..10086
                     /locus_tag="RHX21_001769"
     tRNA            10011..10086
                     /locus_tag="RHX21_001769"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10044..10046,aa:Lys,seq:ttt)
     gene            10233..10308
                     /locus_tag="RHX21_001770"
     tRNA            10233..10308
                     /locus_tag="RHX21_001770"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10266..10268,aa:Lys,seq:ttt)
     gene            10342..10417
                     /locus_tag="RHX21_001771"
     tRNA            10342..10417
                     /locus_tag="RHX21_001771"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10375..10377,aa:Lys,seq:ttt)
     gene            10448..10573
                     /locus_tag="RHX21_001772"
     ncRNA           10448..10573
                     /ncRNA_class="other"
                     /locus_tag="RHX21_001772"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
     gene            10822..11865
                     /gene="nadA"
                     /locus_tag="RHX21_001773"
     CDS             10822..11865
                     /gene="nadA"
                     /locus_tag="RHX21_001773"
                     /EC_number="2.5.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HDV1986963.1"
                     /translation="MSVMFDPDTAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVM
                     VAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEK
                     TILMPTLQAECSLDLGCPVEEFNAFCDAHPDRTVVVYANTSAAVKARADWVVTSSIAV
                     ELIDHLDSLGEKIIWAPDKHLGRYVQKQTGGDILCWQGACIVHDEFKTQALTRLQEEY
                     PDAAILVHPESPQAIVDMADAVGSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPD
                     KELLEAPTAGEGATCRSCAHCPWMAMNGLQSIAEALEQEGSNHEVHVDERLRERALVP
                     LNRMLDFAATLRG"
     gene            11903..12622
                     /gene="pnuC"
                     /locus_tag="RHX21_001774"
     CDS             11903..12622
                     /gene="pnuC"
                     /locus_tag="RHX21_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HDV1986964.1"
                     /translation="MDFFSVQNILVHIPIGAGGYDLSWIEAVGTIAGLLCIGLASLEK
                     ISNYFFGLINVTLFGIIFFQIQLYASLLLQVFFFAANIYGWYAWSRQTSQNEAELKIR
                     WLPLPKALSWLAVCVVSIGLMTVFINPVFAFLTRVAVMIMQALGLQVVMPELQPDAFP
                     FWDSCMMVLSIVAMILMTRKYVENWLLWVIINVISVVIFALQGVYAMSLEYIILTFIA
                     LNGSRMWINSARERGSRALSH"
     gene            complement(12619..13560)
                     /gene="zitB"
                     /locus_tag="RHX21_001775"
     CDS             complement(12619..13560)
                     /gene="zitB"
                     /locus_tag="RHX21_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family zinc transporter ZitB"
                     /protein_id="HDV1986965.1"
                     /translation="MAHSHSHTSSHLPEDNNARRLLYAFGVTAGFMLVEVVGGFLSGS
                     LALLADAGHMLTDTAALLFALLAVQFSRRPPTIRHTFGWLRLTTLAAFVNAIALVVIT
                     ILIVWEAIERFRTPRPVEGGMMMAIAVAGLLANILSFWLLHHGSEEKNLNVRAAALHV
                     LGDLLGSVGAIIAALIIIWTGWTPADPILSILVSLLVLRSAWRLLKDSVNELLEGAPV
                     SLDIAELKRRMCREIPEVRNVHHVHVWMVGEKPVMTLHVQVIPPHDHDALLDQIQHYL
                     MDHYQIEHATIQMEYQPCHGPDCHLNEGVSGHSHHHH"
     gene            complement(13674..14054)
                     /locus_tag="RHX21_001776"
     CDS             complement(13674..14054)
                     /locus_tag="RHX21_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgS-like family protein"
                     /protein_id="HDV1986966.1"
                     /translation="MKMTKLATLFLTATLSLASGAALAADSGAQTNNGQANAAADAGQ
                     VAPDARENVAPNNVDNNGVNTGSGGTMLHSDGSSMNNDGMTKDEEHKNTMCKDGRCPD
                     INKKVQTGDGINNDVDTKTDGTTQ"
     gene            14370..15422
                     /gene="aroG"
                     /locus_tag="RHX21_001777"
     CDS             14370..15422
                     /gene="aroG"
                     /locus_tag="RHX21_001777"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroG"
                     /protein_id="HDV1986967.1"
                     /translation="MNYQNDDLRIKEIKELLPPVALLEKFPATENAANTVAHARKAIH
                     KILKGNDDRLLVVIGPCSIHDPVAAKEYATRLLALREELKDELEIVMRVYFEKPRTTV
                     GWKGLINDPHMDNSFQINDGLRIARKLLLDINDSGLPAAGEFLDMITPQYLADLMSWG
                     AIGARTTESQVHRELASGLSCPVGFKNGTDGTIKVAIDAINAAGAPHCFLSVTKWGHS
                     AIVNTSGNGDCHIILRGGKEPNYSAKHVAEVKEGLNKAGLPAQVMIDFSHANSSKQFK
                     KQMDVCADVCQQIAGGEKAIIGVMVESHLVEGNQSLESGEPLAYGKSITDACIGWEDT
                     DALLRQLANAVKARRG"
     gene            complement(15580..16332)
                     /gene="gpmA"
                     /locus_tag="RHX21_001778"
     CDS             complement(15580..16332)
                     /gene="gpmA"
                     /locus_tag="RHX21_001778"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000301556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HDV1986968.1"
                     /translation="MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKL
                     LKEEGYSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAE
                     TAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDR
                     VIPYWNETILPRMKSGERVIIAAHGNSLRALVKYLDNMSEEEILELNIPTGVPLVYEF
                     DENFKPLKRYYLGNADEIAAKAAAVANQGKAK"
     gene            complement(16537..17577)
                     /gene="galM"
                     /locus_tag="RHX21_001779"
     CDS             complement(16537..17577)
                     /gene="galM"
                     /locus_tag="RHX21_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-epimerase"
                     /protein_id="HDV1986969.1"
                     /translation="MLNETPALAPDGQPYRLLTLRNNAGMVVTLMDWGATLLSARIPL
                     SDGSVREALLGCASPECYQDQAAFLGASIGRYANRIANSRYTFDGETVTLSPSQGVNQ
                     LHGGPEGFDKRRWQIVNQNDRQVLFALSSDDGDQGFPGNLGATVQYRLTDDNRISITY
                     RATVDKPCPVNMTNHVYFNLDGEQSDVRNHKLQILADEYLPVDEGGIPHDGLKSVAGT
                     SFDFRSAKIIASEFLADDDQRKVKGYDHAFLLQAKGDGKKVAAHVWSADEKLQLKVYT
                     TAPALQFYSGNFLGGTPSRGTEPYADWQGLALESEFLPDSPNHPEWPQPDCFLRPGEE
                     YSSLTEYQFIAE"
     gene            complement(17571..18719)
                     /gene="galK"
                     /locus_tag="RHX21_001780"
     CDS             complement(17571..18719)
                     /gene="galK"
                     /locus_tag="RHX21_001780"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001713229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HDV1986970.1"
                     /translation="MSLKEKTQSLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVL
                     PCAIDYQTVISCAPRDDRKVRVMAADYENQLDEFSLDAPIVAHENYQWANYVRGVVKH
                     LQLRNNSFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQE
                     AENQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMPKGVAVVIINSNFKRTL
                     VGSEYNTRREQCETGARFFQQPALRDVTIEEFNAVAHELDPIVAKRVRHILTENARTV
                     EAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVKAVIGDKGGVRMTGG
                     GFGGCIVALIPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC"
     gene            complement(18723..19769)
                     /gene="galT"
                     /locus_tag="RHX21_001781"
     CDS             complement(18723..19769)
                     /gene="galT"
                     /locus_tag="RHX21_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HDV1986971.1"
                     /translation="MTQFNPVDHPHRRYNPLTGQWILVSPHRAKRPWQGAQETPAKQV
                     LPAHDPDCFLCAGNVRVTGDKNPDYTRTYVFTNDFAALMSDTPDAPESNDPLMRCQSA
                     RGTSRVICFSPDHSKTLPELSVAALTEIVKTWQEQTAELGKTYPWVQVFENKGAAMGC
                     SNPHPHGQIWANSFLPNEAEREDRLQKEYFAEQKSPMLVDYVQRELADGSRTVVETEH
                     WLAVVPYWAAWPFETLLLPKAHVLRITDLTDAQRSDLALALKKLTSRYDNLFQCSFPY
                     SMGWHGAPFNGEENQHWQLHAHFYPPLLRSATVRKFMVGYEMLAETQRDLTAEQAAER
                     LRAVSDIHFREFGV"
     gene            complement(19779..20795)
                     /gene="galE"
                     /locus_tag="RHX21_001782"
     CDS             complement(19779..20795)
                     /gene="galE"
                     /locus_tag="RHX21_001782"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415280.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HDV1986972.1"
                     /translation="MRVLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVI
                     ERLGGKHPTFVEGDIRNEALMTEILHDHAIDTVIHFAGLKAVGESVQKPLEYYDNNVN
                     GTLRLISAMRAANVKNFIFSSSATVYGDQPKIPYVESFPTGTPQSPYGKSKLMVEQIL
                     TDLQKAQPDWSIALLRYFNPVGAHPSGDMGEDPQGIPNNLMPYIAQVAVGRRDSLAIF
                     GNDYPTEDGTGVRDYIHVMDLADGHVVAMEKLANKPGVHIYNLGAGVGNSVLDVVNAF
                     SKACGKPVNYHFAPRREGDLPAYWADASKADRELNWRVTRTLDEMAQDTWHWQSRHPQ
                     GYPD"
     gene            complement(21056..22528)
                     /gene="modF"
                     /locus_tag="RHX21_001783"
     CDS             complement(21056..22528)
                     /gene="modF"
                     /locus_tag="RHX21_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter ATP-binding protein
                     ModF"
                     /protein_id="HDV1986973.1"
                     /translation="MSSLQILQGTFRLSDTKTLQLPQLTLNAGDSWAFVGSNGSGKSA
                     LARALAGELPLLKGERQSQFSHITRLSFEQLQKLVSDEWQRNNTDMLGPGEDDTGRTT
                     AEIIQDEVKDAPRCMQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILD
                     EPFDGLDVASRQQLAERLASLHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGA
                     KEELLQQALVAQLAHSEQLEGVQLPEPDEPSARHALPTNEPRIVLNNGVVSYNDRPIL
                     NNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDI
                     KKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQQKLVQQWLDILGIDK
                     RTADAPFHSLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISE
                     GETQLLFVSHHAEDAPACITHRLEFVPDGGLYRYVLTKIY"
     gene            complement(22596..23384)
                     /gene="modE"
                     /locus_tag="RHX21_001784"
     CDS             complement(22596..23384)
                     /gene="modE"
                     /locus_tag="RHX21_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum-dependent transcriptional regulator"
                     /protein_id="HDV1986974.1"
                     /translation="MQAEILLTLKLQQKLFADPRRISLLKHIALSGSISQGAKDAGIS
                     YKSAWDAINEMNQLSEHILVERATGGKGGGGAVLTRYGQRLIQLYDLLAQIQQKAFDV
                     LSDDDALPLNSLLAAISRFSLQTSARNQWFGTITARDHDDVQQHVDVLLADGKTRLKV
                     AITAQSGARLGLDEGKEVLILLKAPWVGITQDEAVAQNADNQLPGIISHIERGAEQCE
                     VLMALPDGQTLCATVPVNEATSLQQGQNVTAYFNADSVIIATLC"
     gene            23513..23662
                     /gene="acrZ"
                     /locus_tag="RHX21_001785"
     CDS             23513..23662
                     /gene="acrZ"
                     /locus_tag="RHX21_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux pump accessory protein AcrZ"
                     /protein_id="HDV1986975.1"
                     /translation="MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQ
                     PGQNH"
     gene            23829..24602
                     /gene="modA"
                     /locus_tag="RHX21_001786"
     CDS             23829..24602
                     /gene="modA"
                     /locus_tag="RHX21_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDV1986976.1"
                     /translation="MARKWLNLFAGAALSFAVAGNALADEGKITVFAAASLTNAMQDI
                     ATQYKKEKGVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAVDKKAIDTATRQ
                     TLLGNSLVVVAPKASEQKDFIIDSKTNWTSLLNGGRLAVGDPEHVPAGIYAKEALQKL
                     GAWDTLSPKLAPAEDVRGALALVERNEAPLGIVYGSDAVASKGVKVVATFPEDSHKKV
                     EYPVAVVEGHNNATVKAFYDYLKGPQAAEIFKRYGFTTK"
     gene            24602..25291
                     /gene="modB"
                     /locus_tag="RHX21_001787"
     CDS             24602..25291
                     /gene="modB"
                     /locus_tag="RHX21_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HDV1986977.1"
                     /translation="MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGK
                     ALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERLYDWFGITFAFSWRGAVLAAAVM
                     SFPLMVRAIRLALEGVDVKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARS
                     LGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEW
                     LARISRERAGR"
     gene            25294..26352
                     /gene="modC"
                     /locus_tag="RHX21_001788"
     CDS             25294..26352
                     /gene="modC"
                     /locus_tag="RHX21_001788"
                     /EC_number="7.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein
                     ModC"
                     /protein_id="HDV1986978.1"
                     /translation="MLELNFSQTLGNHCLTINETLPANGITAIFGVSGAGKTSLINAI
                     SGLTRPQKGRIVLNGRVLNDAEKGICLTPEKRRVGYVFQDARLFPHYKVRGNLRYGMA
                     KSMVDQFDKLVALLGIEPLLDRLPGSLSGGEKQRVAIGRALLTAPELLLLDEPLASLD
                     IPRKRELLPYLQRLTREINIPMLYVSHSLDEILHLADRVMVLENGQVKAFGALEEVWG
                     SSVMNPWLPKEQQSSILKVTVLEHHPHYAMTALALGDQHLWVNKLDEPLQAALRIRIQ
                     ASDVSLVLQPPQQTSIRNVLRAKVVNSYDDNGQVEVELEVGGKTLWARISPWARDELA
                     IKPGLWLYAQIKSVSITA"
     gene            complement(26353..27171)
                     /gene="ybhA"
                     /locus_tag="RHX21_001789"
     CDS             complement(26353..27171)
                     /gene="ybhA"
                     /locus_tag="RHX21_001789"
                     /EC_number="3.1.3.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyridoxal
                     phosphate/fructose-1,6-bisphosphate phosphatase"
                     /protein_id="HDV1986979.1"
                     /translation="MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYQLIIVTG
                     RHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVNKALQLIEMLNEHHI
                     HGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFAL
                     THDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENV
                     VAFGDNFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI"
     gene            27326..28321
                     /gene="pgl"
                     /locus_tag="RHX21_001790"
     CDS             27326..28321
                     /gene="pgl"
                     /locus_tag="RHX21_001790"
                     /EC_number="3.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconolactonase"
                     /protein_id="HDV1986980.1"
                     /translation="MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVS
                     PDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYN
                     AGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSDDG
                     HLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTL
                     DMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQ
                     PRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH"
     gene            complement(28362..29315)
                     /locus_tag="RHX21_001791"
     CDS             complement(28362..29315)
                     /locus_tag="RHX21_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001473949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV1986981.1"
                     /translation="MKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEED
                     LHIQLFERTTRKVTLTKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLACIPT
                     AVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDFT
                     PLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLD
                     WFYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKD
                     AVLSPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIS"
     gene            29499..30551
                     /locus_tag="RHX21_001792"
     CDS             29499..30551
                     /locus_tag="RHX21_001792"
                     /EC_number="5.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalomesaconate tautomerase"
                     /protein_id="HDV1986982.1"
                     /translation="MKKIPCVMMRGGTSRGAFLLAEHLPEDQTQRDKILMAIMGSGND
                     LEIDGIGGGNPLTSKVAIISRSSDPRADVDYLFAQVIVHEQRVDTTPNCGNMLSGVGA
                     FAIENGLIAATSPVTRVRIRNVNTGTFIEADVQTPNGVVEYEGSARIDGVPGTAAPVA
                     LTFLNAAGTKTGKVFPTDNQIDYFDDVPVTCIDMAMPVVIIPAEYLGKTGYELPAELD
                     ADKALLARIESIRLQAGKAMGLGDVSNMVIPKPVLISPAQKGGAINVRYFMPHSCHRA
                     LAITGAIAISSSCALEGTVTRQIVPSVGYGNINIEHPSGALDVHLSNEGQDATTLRAS
                     VIRTTRKIFSGEVYLP"
     gene            30627..32060
                     /locus_tag="RHX21_001793"
     CDS             30627..32060
                     /locus_tag="RHX21_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HDV1986983.1"
                     /translation="MNKKSLWKLILILAIPCIIGFMPAPAGLSELAWVLFGIYLAAIV
                     GLVIKPFPEPVVLLIAVAASMVVVGNLSDGAFKTTAVLSGYSSGTTWLVFSAFTLSAA
                     FVTTGLGKRIAYLLIGKIGNTTLGLGYVTVFLDLVLAPATPSNTARAGGIVLPIINSV
                     AVALGSEPEKSPRRVGHYLMMSIYMVTKTTSYMFFTAMAGNILALKMINDILHLQISW
                     GGWALAAGLPGIIMLLVTPLVIYTMYPPEIKKVDNKTIAKAGLAELGPMKIREKMLLG
                     VFVLALLGWIFSKSLGVDESTVAIVVMATMLLLGIVTWEDVVKNKGGWNTLIWYGGII
                     GLSSLLSKVKFFEWLAEVFKNNLAFDGHGNVAFFVIIFLSIIVRYFFASGSAYIVAML
                     PVFAMLANVSGAPLMLTALALLFSNSYGGMVTHYGGAAGPVIFGVGYNDIKSWWLVGA
                     VLTILTFLVHITLGVWWWNMLIGWNML"
     gene            32243..34504
                     /locus_tag="RHX21_001794"
     CDS             32243..34504
                     /locus_tag="RHX21_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415292.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydratase"
                     /protein_id="HDV1986984.1"
                     /translation="MIKLSEKGVFLASNNEIIAEEHFTGEIKKEEAKKGTIAWSILSS
                     HNTSGNMDKLKIKFDSLASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGT
                     INGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTM
                     AVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPAPYVGPQDVALAIIGAVFKNGYVK
                     NKVMEFVGPGVSALSTDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQL
                     NPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEIDTLNQNLTDILREIEIESERVAH
                     GKAKLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPS
                     SQPVFMDLAKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREG
                     SKPANGQMSAVALMDARSIAATAANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQG
                     FVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTTDELIPSGETSSYRS
                     NPIGLAEFTLSRRDPGYVGRSKATAELENQRLAGNVSELTEVFARIKQIAGQEHIDPL
                     QTEIGSMVYAVKPGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQM
                     AEVPTFEVGDYIYIPGIKAALDNPGTTFKGYVIHEDAPVTEITLYMESLTAEEREIIK
                     AGSLINFNKNRQM"
     gene            complement(34646..35929)
                     /locus_tag="RHX21_001795"
     CDS             complement(34646..35929)
                     /locus_tag="RHX21_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative acyl-CoA thioester hydrolase"
                     /protein_id="HDV1986985.1"
                     /translation="MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPI
                     LSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVD
                     AAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPA
                     DWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENT
                     LGDSVDAGNHPAVALRTDGDQVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVT
                     NSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFN
                     AFGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGSVD
                     DNDEIQRNLNDTNYNRMWEYNNRGVGSKVVAEAKK"
     gene            complement(36081..36557)
                     /locus_tag="RHX21_001796"
     CDS             complement(36081..36557)
                     /locus_tag="RHX21_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase inhibitor"
                     /protein_id="HDV1986986.1"
                     /translation="MKLISNDLRDGDKLPHRHVFNGMGYDGDNISPHLAWDDVPAGTK
                     SFVVTCYDPDAPTGSGWWHWVVVNLPADTRVLPQGFGSGLVAMPDGVLQTRTDFGKTG
                     YDGAAPPKGETHRYIFTVHALDIERIDVDEGASGAMVGFNVHFHSLASASITAMFS"
     gene            complement(36616..37905)
                     /gene="bioA"
                     /locus_tag="RHX21_001797"
     CDS             complement(36616..37905)
                     /gene="bioA"
                     /locus_tag="RHX21_001797"
                     /EC_number="2.6.1.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase"
                     /protein_id="HDV1986987.1"
                     /translation="MTTDDLAFDQRHIWHPYTSMTSPLPVYPVASAEGCELILSDGRR
                     LVDGMSSWWAAIHGYNHPQLNAAMKSQIDAMSHVMFGGITHAPAIELCRKLVAMTPQP
                     LECVFLADSGSVAVEVAMKMALQYWQAKGEARHRFLTFRNGYHGDTFGAMSVCDPDNS
                     MHSLWKGYLPENLFAPAPQSRMDGEWDERDMVGFARLMAAHRHEIAAVIIEPIVQGAG
                     GMRMYHPEWLKRIRKMCDREGILLIADEIATGFGRTGKLFACEHAEIAPDILCLGKAL
                     TGGTMTLSATLTTREVAETISNGEAGCFMHGPTFMGNPLACAAANASLAILESGDWQQ
                     QVAAIEVQLREQLAPARDAEMVADVRVLGAIGVVETTRPVNMAALQKFFVEQGVWIRP
                     FGKLIYLMPPYIILPQQLQRLTAAVNRAVQDETFFCQ"
     gene            37992..39032
                     /gene="bioB"
                     /locus_tag="RHX21_001798"
     CDS             37992..39032
                     /gene="bioB"
                     /locus_tag="RHX21_001798"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HDV1986988.1"
                     /translation="MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVST
                     LLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAW
                     KNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEF
                     YGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPES
                     VPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMC
                     FMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMT
                     PDTDEYYNAAAL"
     gene            39029..40183
                     /gene="bioF"
                     /locus_tag="RHX21_001799"
     CDS             39029..40183
                     /gene="bioF"
                     /locus_tag="RHX21_001799"
                     /EC_number="2.3.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-amino-7-oxononanoate synthase"
                     /protein_id="HDV1986989.1"
                     /translation="MSWQEKINAALDARRAADALRRRYPVAQGAGRWLVADDRQYLNF
                     SSNDYLGLSHHPQIIRAWQQGAEQFGIGSGGSGHVSGYSVAHQALEEELAEWLGYSRA
                     LLFISGFAANQAVIAAMMAKEDRIVADRLSHASLLEAASLSPSQLRRFVHNDVTHLAR
                     LLASPCPGQQLVVTEGVFSMDGDIAPLAEIQQVTQQHNGWLMVDDAHGTGVIGEQGRG
                     SCWLQKVKPELLVVTFGKGFGVSGAAVLCSSTVADYLLQFARHLIYSTSMPPAQAQAL
                     RASLAVIRRDEGDARREKLVSLIARFRAGVQDLPFTLADSCSAIQPLIVGDNSRALQL
                     AEKLRQQGCWVTAIRPPTVPAGTARLRLTLTAAHEMQDIDRLLEVLHGNG"
     gene            40170..40925
                     /gene="bioC"
                     /locus_tag="RHX21_001800"
     CDS             40170..40925
                     /gene="bioC"
                     /locus_tag="RHX21_001800"
                     /EC_number="2.1.1.197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonyl-ACP O-methyltransferase BioC"
                     /protein_id="HDV1986990.1"
                     /translation="MATVNKQAIAAAFGRAAALYEQHADLQRQSADVLLAMLPQRKYT
                     HVLDAGCGPGWMSRHWRERHAQVTALDLSPPMLVQARQKDAADHYLAGDIESLPLATA
                     TFDLAWSNLAVQWCGNLSTALRELYRVVRPGGVVAFTTLVQGSLPELHQAWQAVDERP
                     HANRFLPPDEIEQSLNGVHYQHHIQPITLWFDDALSAMRSLKGIGATHLHEGRDPRIL
                     TRSQLQRLQLAWPQQQGRYPLTYHLFLGVIARE"
     gene            40918..>41587
                     /gene="bioD"
                     /locus_tag="RHX21_001801"
     CDS             40918..>41587
                     /gene="bioD"
                     /locus_tag="RHX21_001801"
                     /EC_number="6.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent dethiobiotin synthetase BioD"
                     /protein_id="HDV1986991.1"
                     /translation="MSKRYFVTGTDTEVGKTVASCALLQAAKAVGYRTAGYKPVASGS
                     EKTPEGLRNSDALALQRNSSLQLDYATVNPYTFAEPTSPHIISAQEGRPIESLVMSAG
                     LRALEQQADWVLVEGAGGWFTPLSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTA
                     QAIQHAGLTLAGWVANDVTPPGKRHAEYMTTLTRMIPAPLLGEIPWLAENPENAATGK
                     YINLA"
BASE COUNT         9966 a        10310 c        11099 g        10212 t
ORIGIN      
        1 aaatgggcat caaaaagaga taaattgttc tcgatcaaat tggctgaaag gcggtaattt
       61 agctataaat tgatcaccgt cgaaaaatgc aaatttgctt caacaaaaac ctgtttattg
      121 taaggatttt gcggcgtaat atatacgtgg gatcaatttg agtttttatt aacatgtttg
      181 caacctttct ttacgccgtt tttgtgtgca ttcacatggt atgatgaaag tgttcaaaca
      241 aatttctatt ggggcatgcg tgtgaccctt tctaacgggg ttcactctcg gagtcttcat
      301 gcgatgagca aggagtcatg atgttagata tagtcgaact gtcgcgctta cagtttgcct
      361 tgaccgcgat gtaccacttc ctttttgtgc cactgacgct cggtatggcg ttcctgctgg
      421 ccattatgga aacggtctac gtcctctccg gcaaacagat ttataaagat atgaccaagt
      481 tctggggcaa gttgtttggt atcaacttcg ctctgggtgt ggctaccggt ctgaccatgg
      541 agttccagtt cgggactaac tggtcttact attcccacta tgtaggggat atcttcggtg
      601 cgccgctggc aatcgaaggt ctgatggcct tcttcctcga atccaccttt gtaggtctgt
      661 tcttcttcgg ttgggatcgt ctgggtaaag ttcagcatat gtgtgtcacc tggctggtgg
      721 cgctcggttc aaacctgtcc gcactgtgga ttctggttgc gaacggctgg atgcaaaacc
      781 caatcgcgtc cgatttcaac tttgaaacta tgcgtatgga gatggtgagc ttctccgagc
      841 tggtgcttaa cccggttgct caggtgaaat tcgttcacac tgtagcgtct ggttatgtga
      901 ctggcgcgat gttcatcctc ggtatcagcg catggtatat gctgaaaggt cgtgacttcg
      961 ccttcgctaa acgctccttt gctatcgctg ccagcttcgg tatggctgct gttctgtctg
     1021 ttattgttct gggtgatgaa tccggctacg aaatgggcga cgtgcagaaa accaaactgg
     1081 ctgctattga agccgagtgg gaaacgcaac ctgcgcctgc tgcctttact ctgttcggca
     1141 ttcctgatca ggaagaggag acgaacaaat ttgcgattca gatcccttac gcactgggca
     1201 tcattgcaac gcgttccgtg gataccccgg ttatcggcct gaaagagctg atggtgcagc
     1261 atgaagaacg cattcgtaac gggatgaagg cgtactctct gctcgaacaa ctgcgttctg
     1321 gttctaccga ccaggcggtt cgtgaccagt tcaatagcat gaagaaagac ctcggttacg
     1381 gtctgctgct gaaacgctat acgccaaacg tggctgatgc gactgaagcg cagattcaac
     1441 aggcaaccaa agactccatc ccgcgtgtag cgccgctgta ctttgcgttc cgtatcatgg
     1501 tggcgtgtgg cttcctgctt ctggcaatca tcgcgctctc tttctggagt gtcatccgca
     1561 accgcattgg cgagaaaaaa tggcttctgc gcgccgcgct gtacggtatt ccgctgccgt
     1621 ggattgctgt agaagcgggc tggttcgtgg ctgaatatgg ccgccaaccg tgggctatcg
     1681 gtgaggtgct gccgacagct gtggcgaact cgtcactgac cgcaggcgat ctcatcttct
     1741 caatggtgct gatttgcggc ctgtataccc tgttcctggt ggcagaattg ttcttaatgt
     1801 tcaaatttgc acgcctcggc ccaagcagcc tgaaaaccgg tcgctatcac tttgagcagt
     1861 cttccacgac tactcagccg gcacgctaag acaggagtcg tcaaatgatc gattatgaag
     1921 tattgcgttt tatctggtgg ctgctggttg gcgttctgct gattggtttt gcagtcactg
     1981 acggtttcga catgggggtg ggcatgctca cccgtttcct cggtcgtaac gacaccgagc
     2041 gtcgaattat gattaactcc attgcaccac actgggacgg taaccaggtt tggctgatca
     2101 ccgcgggcgg cgcactcttt gctgcctggc cgatggtcta tgccgctgcg ttctccggct
     2161 tctatgtggc gatgatcctc gtgctggcgt ctttgttctt ccgtccggtc ggttttgact
     2221 accgctccaa gattgaagaa acccgctggc gtaacatgtg ggactggggc atcttcattg
     2281 gtagcttcgt tccgccgctg gtaattggtg tagcgttcgg taacctgttg cagggcgtac
     2341 cgttcaacgt tgatgaatat ctgcgtctgt actacaccgg taacttcttc cagttgctta
     2401 acccgttcgg cctgctggca ggcgtggtga gcgtagggat gatcattact cagggcgcaa
     2461 cctatctgca aatgcgtacc gtgggcgaac tgcacctgcg tacccgtgca acggctcagg
     2521 tggctgcgct ggtgacactg gtctgtttcg cactggctgg cgtatgggtg atgtacggta
     2581 tcgatggtta tgtcgtgaaa tcgacaatgg accattacgc agcctctaac ccactgaata
     2641 aagaagtggt tcgtgaagct ggcgcatggc tggttaactt caacaacacg ccaattctgt
     2701 gggctattcc ggcactgggt gtggttctgc cgctgctgac catcctgact gcacgtatgg
     2761 ataaagccgc gtgggcgttt gtgttctcct ccctgacgct ggcctgcatc atcctgacag
     2821 ccggtatcgc aatgttcccg tttgtgatgc cgtccagcac catgatgaac gcaagtctga
     2881 caatgtggga tgcaacttcc agccagctga cgcttaacgt catgacctgg gttgcggtgg
     2941 ttctggtacc gatcattctg ctctacaccg cctggtgtta ctggaaaatg ttcggtcgta
     3001 tcaccaaaga agatattgaa cgtaacaccc actctctgta ctaagtaagg agctaaaaat
     3061 gtggtatttc gcatggattc tgggaacgct tcttgcctgt tcgtttgggg taatcaccgc
     3121 gctggcgctt gaacacgtcg aatcaggcaa agccggtcaa gaagacatct gatgagtaag
     3181 attatcgcga ctttgtatgc ggtaatggac aagcgccccc tgcgggcgct ttccttcgtg
     3241 atggcgcttc tgttagcagg atgtatgttt tgggacccat ctcgttttgc cgcgaagacc
     3301 agtgaactgg aaatctggca tggtttattg ctgatgtggg ccgtctgtgc tggtgtgatt
     3361 cacggcgtgg gctttcgtcc gcagaaggtt ctttggcaag ggattttttg cccattgctt
     3421 gccgatattg ttctcattgt cgggctgatt ttcttcttct tttaaatcag aattctcttt
     3481 aaaaaattat gggccgctcc aggcccataa atttttacgc tcccttaact tgccctcatt
     3541 cccaaacctc aatcgcgcgc gtatagtagc agcgtttaaa agctctaact tttgttgcat
     3601 taccgggatg taaagtgaat acaacgctgt ttcgatggcc ggttcgcgtc tactatgaag
     3661 ataccgatgc cggtggtgtg gtgtaccacg ccagttacgt cgctttttat gaaagagcac
     3721 gcacagagat gctgcgtcat catcacttca gtcagcaggc gctgatggct gaacgcgttg
     3781 cctttgtggt acgtaaaatg acggtggaat attacgcacc tgcgcggctc gacgatatgc
     3841 tcgaaataca gactgaaata acatcaatgc gtggcacctc tttggttttc acgcaacgta
     3901 ttgtcaacgc cgagaatact ttgctgaatg aagcagaggt tctggttgtt tgcgttgacc
     3961 cactcaaaat gaagcctcgt gcgcttccca agtctattgt cgcggagttt aagcagtgac
     4021 tgacatgaat atccttgatt tgttcctgaa ggctagcctt ctggttaaac ttatcatgtt
     4081 gattttgatt ggtttttcaa tcgcatcttg ggccattatt atccagcgga cccgtattct
     4141 taacgcagcg gcgcgcgaag ccgaagcgtt tgaagataaa ttctggtctg gaatcgaact
     4201 ctctcgcctc tatcaagaga gccaggggaa acgggataat ctgactggtt cggaacaaat
     4261 cttttacagc gggttcaaag agtttgtgcg cctgcatcgt gccaatagcc atgcgccgga
     4321 agccgtagtg gaaggggcgt cgcgtgctat gcgtatctcc atgaaccgtg aacttgaaaa
     4381 tctggaaacg cacattccgt tcctcggtac ggttggctcc atcagcccgt atattggtct
     4441 gtttggtacg gtctggggga tcatgcacgc ctttatcgcc ctcggggcgg taaaacaagc
     4501 aacactgcaa atggttgcgc ccggtatcgc agaagcgttg attgcgactg caattggtct
     4561 gttcgccgca attccggcgg taatggctta taaccgcctc aaccagcgcg taaacaaact
     4621 ggaactgaat tacgacaact ttatggaaga gtttaccgcg attctgcacc gccaggcgtt
     4681 taccgttagc gagagcaaca aggggtaagc catggccaga gcgcgtggac gaggtcgtcg
     4741 cgatctcaag tccgaaatca acattgtacc gttgctggac gtactgctgg tgctgttgct
     4801 gatctttatg gcgacagcgc ccatcatcac ccagagcgtg gaggtcgatc tgccagacgc
     4861 tactgaatca caggcggtga gcagtaacga taatccgcca gtgattgttg aagtgtctgg
     4921 tattggtcag tacaccgtgg tggttgagaa agatcgcctg gagcgtttac caccagagca
     4981 ggtggtggcg gaagtgtcca gccgtttcaa ggccaacccg aaaacggtct ttctgatcgg
     5041 tggcgcaaaa gatgtgcctt acgatgaaat aattaaagca ctgaacttgt tacatagtgc
     5101 gggtgtgaaa tcggttggtt taatgacgca gcctatctaa acatctgcgt ttcccttgct
     5161 tgaaagagag cgggtaacag gcgaacagtt tttggaaacc gagagtgtca aaggcaaccg
     5221 aacaaaacga caagctcaag cgggcgataa ttatttcagc agtgctgcat gtcatcttat
     5281 ttgcggcgct gatctggagt tcgttcgatg agaatataga agcttcagcc ggaggcggcg
     5341 gtggttcgtc catcgacgct gtcatggttg attcaggtgc ggtagttgag cagtacaaac
     5401 gcatgcaaag ccaggaatca agcgcgaagc gttctgatga acagcgcaag atgaaggaac
     5461 agcaggctgc tgaagaactg cgtgagaaac aagcggctga acaggaacgc ctgaagcaac
     5521 ttgagaaaga gcggttagcg gctcaggagc agaaaaagca ggctgaagaa gccgcaaaac
     5581 aggccgagtt aaagcagaag caagctgaag aggcggcagc gaaagcggcg gcagatgcta
     5641 aagcgaaggc cgaagcagat gctaaagctg cggaagaagc agcgaagaaa gcggctgcag
     5701 acgcaaagaa aaaagcagaa gcagaagccg ccaaagccgc agccgaagcg cagaaaaaag
     5761 ccgaggcagc cgctgcggca ctgaagaaga aagcggaagc ggcagaagca gctgcagctg
     5821 aagcaagaaa gaaagcggca actgaagctg ctgaaaaagc caaagcagaa gctgagaaga
     5881 aagcggctgc tgaaaaggct gcagctgata agaaagcggc agcagagaaa gctgcagccg
     5941 acaaaaaagc agcagaaaaa gcggctgctg aaaaggcagc agctgataag aaagcagcgg
     6001 cagaaaaagc cgccgcagac aaaaaagcgg cagcggcaaa agctgcagct gaaaaagccg
     6061 ctgcagcaaa agcggccgca gaggcagatg atattttcgg tgagctaagc tctggtaaga
     6121 atgcaccgaa aacgggggga ggggcgaaag ggaacaatgc ttcgcctgcc gggagtggta
     6181 atactaaaaa caatggcgca tcaggggccg atatcaataa ctatgccggg cagattaaat
     6241 ctgctatcga aagtaagttc tatgacgcat cgtcctatgc aggcaaaacc tgtacgctgc
     6301 gcataaaact ggcacccgat ggtatgttac tggatatcaa acctgaaggt ggcgatcccg
     6361 cactttgtca ggctgcgttg gcagcagcta aacttgcgaa gatcccgaaa ccaccaagcc
     6421 aggcagtata tgaagtgttc aaaaacgcgc cattggactt caaaccgtaa tcgcgatgtt
     6481 gactgttcgg acggtcaaca tcaggcaccg gttgccacgg ggttctggta gttttgtgta
     6541 ttttagtttg ttaacattct gctaaattat cgtgggccat cggtccagat aagggagata
     6601 tgatgaagca ggcattacga gtagcatttg gttttctcat actgtgggca tcagttctgc
     6661 atgctgaagt ccgcattgtg atcgacagcg gtgtagattc cggtcgtcct attggtgttg
     6721 ttcctttcca gtgggcgggg cctggtgcgg cacctgaaga tattggcggc atcgttgctg
     6781 ctgacttgcg taacagcggt aaatttaatc cgttagatcg cgctcgtctg ccacagcagc
     6841 cgggtagtgc gcaggaagta caaccagctg catggtccgc actgggcatt gacgctgtag
     6901 ttgtcggtca ggtcactccg aatccggatg gttcttacaa tgttgcttat caacttgttg
     6961 acactggcgg cgcaccgggt actgtacttg ctcagaactc gtacaaagtg aacaagcagt
     7021 ggctgcgtta tgctggtcat accgccagtg atgaagtgtt tgaaaaactg accggcatta
     7081 aaggtgcgtt ccgtactcgt attgcctacg ttgttcagac caacggcggt cagttcccgt
     7141 atgaactgcg cgtatctgac tatgacggtt acaaccagtt tgtcgttcac cgttcaccgc
     7201 agccgctgat gtctccggcg tggtcaccag acggttctaa actggcttat gtgaccttcg
     7261 aaagcggtcg ttccgcgctg gttattcaga cgctggcaaa tggcgctgta cgtcaggtgg
     7321 cttcattccc gcgtcacaac ggtgcacctg cattctcgcc agacggcagc aaactggcat
     7381 tcgccttgtc gaaaaccggt agtctgaacc tgtacgtaat ggatttggct tctggtcaga
     7441 tccgccaggt gactgatggt cgcagtaaca ataccgaacc gacctggttc ccggatagcc
     7501 agaacctggc atttacttct gaccaggccg gtcgtccgca ggtttataaa gtgaatatca
     7561 acggcggtgc gccacaacgt attacctggg aaggttcgca gaaccaggat gcggatgtca
     7621 gcagcgacgg taaatttatg gtaatggtca gctccaatgg tgggcagcag cacattgcca
     7681 aacaagatct ggcaacggga ggcgtacaag ttctgtcgtc cacgttcctg gatgaaacgc
     7741 caagtctggc acctaacggc actatggtaa tctacagctc ttctcagggg atgggatccg
     7801 tgctgaattt ggtttctaca gatgggcgtt tcaaagcgcg tcttccggca actgatggac
     7861 aggtcaaatt ccctgcctgg tcgccgtatc tgtgataata attaattgaa tagtaaagga
     7921 atcattgaaa tgcaactgaa caaagtgctg aaagggctga tgattgctct gcctgttatg
     7981 gcaattgcgg catgttcttc caacaagaac gccagcaatg acggcagcga aggcatgctg
     8041 ggtgccggca ctggtatgga tgcgaacggc ggcaacggca acatgtcttc cgaagagcag
     8101 gctcgtctgc aaatgcaaca gctgcagcag aacaacatcg tttacttcga tctggacaag
     8161 tacgatatcc gttctgactt cgctcaaatg ctggatgcac atgcaaactt cctgcgtagc
     8221 aacccgtctt acaaagtcac cgtagaaggt cacgcggacg aacgtggtac tccggaatac
     8281 aacatctccc tgggtgaacg tcgtgcgaac gccgttaaga tgtacctgca gggtaaaggc
     8341 gtttctgcag accagatctc catcgtttct tacggtaaag aaaaacctgc agtactgggt
     8401 catgacgaag cggcatactc caaaaaccgt cgtgcggtac tggtttacta agagaattgc
     8461 atgagcagta acttcagaca tcaactattg agtctgtcgt tactggttgg tatagcggcc
     8521 ccctgggccg cttttgctca ggcaccaatc agtagtgtcg gctcaggctc ggtcgaagac
     8581 cgcgtcactc aacttgagcg tatttctaat gctcacagcc agcttttaac ccaactccag
     8641 caacaacttt ctgataatca atccgatatt gattccctgc gtggtcagat tcaggaaaat
     8701 cagtatcaac tgaatcaggt cgtggagcgg caaaagcaga tcctgttgca gatcgacagc
     8761 ctcagcagcg gtggtgcagc ggcgcaatca accagcagcg atcaaagcgg tgcggcggca
     8821 tcaacgacgc cgacagctga tgctggtact gcgaatgctg gcgcgccggt gaaaagcggc
     8881 gatgcaaaca cggattacaa tgcagctatt gcgctggtgc aggataaatc ccgccaggat
     8941 gacgcaatgg tggcatttca gaatttcatc aaaaattacc ctgattcaac ttacctgcca
     9001 aacgccaatt attggctggg tcagttaaac tacaacaagg gtaaaaaaga tgatgcggcg
     9061 tactattttg cttcggtagt gaaaaactat ccgaagtcac caaaggctgc tgatgcgatg
     9121 tttaaagtcg gcgtcatcat gcaggacaaa ggtgacaccg caaaagcgaa agccgtatac
     9181 cagcaggtta tcagtaaata ccctggtact gatggcgcta aacaggcaca aaaacgtctg
     9241 aacgcgatgt aatgcataac acacgaccag aagtcgcatt atttctggtc gtgtcgtgcg
     9301 aatcataagc agttgagtga tctgcatcga aatttttgtt gcgctcaagt ctgaaatcag
     9361 taatatatgc cgccgttgcc acgggatatc aaacaaaccg aaagcaacga aaaagtgggt
     9421 cgttagctca gttggtagag cagttgactt ttaatcaatt ggtcgcaggt tcgaatcctg
     9481 cacgacccac caatcgctaa ggtggaagcg gtagtaaaac gtgaaggata acgttgcatc
     9541 agcaacggcc cgaagggcga gacgaagtcg agtcatcctg cacgacccac cactaacata
     9601 gttagttgta gtatccagcg tagtattggg tgattagctc agctgggaga gcacctccct
     9661 tacaaggagg gggtcggcgg ttcgatcccg tcatcaccca ccaccgggtc gttagctcag
     9721 ttggtagagc agttgacttt taatcaattg gtcgcaggtt cgaatcctgc acgacccacc
     9781 agttttagca tcgaagacaa gatgttaagc gtgtaggata acgttgcgtc agcaacggcc
     9841 cgtagggcga gcgaagcgag tcatcctgca cgacccacca ctaattacgg tgggttcggt
     9901 ggaagtagtt tgtagtatcc agcgcagtat cgggtgatta gctcagctgg gagagcacct
     9961 cccttacaag gagggggtcg gcggttcgat cccgtcatca cccaccactc gggtcgttag
    10021 ctcagttggt agagcagttg acttttaatc aattggtcgc aggttcgaat cctgcacgac
    10081 ccaccaattt taacatcaaa ctcagatgtt aagcgtgaag gataacgttg cgccagcaac
    10141 ggcccgtagg gcaagcgaag cgagtcatcc tgcacgacac accaatctta aagattggcc
    10201 ccgagtagaa atctttcagg taacacccgt atgggtcgtt agctcagttg gtagagcagt
    10261 tgacttttaa tcaattggtc gcaggttcga atcctgcacg acccaccatc ctgaatgatt
    10321 aaagcagcat aatcccgcaa ggggtcgtta gctcagttgg tagagcagtt gacttttaat
    10381 caattggtcg caggttcgaa tcctgcacga cccaccaatg taaaaaagcg ccctaaaggc
    10441 gcttttttgc tatctgcgat actcaaagat tcgaacctgc agcaggtttg agttgagcgc
    10501 agcgaaacaa cggagccgct cgcggcgacg gcccgaaggg cgagcgaagc gagtcatcct
    10561 gcacgaccca ccaatgtaaa aaagcgccct aaaggcgctt ttttgctatt caggcatcct
    10621 caatttcact ttgtaaacct gatgacatcg tcagagctta ctgtgcaagc aactctacgt
    10681 cggtggaatt aggcgtaatt cgagtgactt ttccccacca ttcgactatc ttgtttagca
    10741 tataaaacaa attacaccga taacagcgaa tattacgcta atgtcggttt taacgttaag
    10801 cctgtaaaac gagatggtaa gatgagcgta atgtttgatc cagacacggc gatttatcct
    10861 ttccccccga agccgacgcc gttaagcatt gatgaaaaag cgtattaccg cgagaagata
    10921 aaacgtctgc taaaagaacg taatgcggtg atggttgccc actactatac cgatcccgaa
    10981 attcaacaac tggcagaaga aaccggtggc tgtatttctg attctctgga aatggcgcgc
    11041 ttcggtgcaa agcatcccgc ttctactttg ttagtcgctg gggtgagatt tatgggagaa
    11101 accgccaaaa ttctcagtcc ggaaaaaaca attctgatgc cgacacttca ggctgaatgt
    11161 tcactggatc tcggctgccc tgttgaagaa tttaacgcat tttgcgatgc ccatcccgat
    11221 cgtactgtcg tcgtctacgc caacacttct gctgcggtaa aagcgcgcgc agattgggtg
    11281 gtaacttcaa gcattgccgt cgaacttatt gatcatcttg atagtttggg tgaaaaaatc
    11341 atctgggcac ccgacaaaca tctggggcgt tacgtgcaaa aacagacggg tggagacatt
    11401 ctatgctggc agggtgcctg tattgtgcat gatgaattta agactcaggc gttaacccgc
    11461 ttgcaagaag aatacccgga tgctgccata ctggtgcatc cagaatcacc acaagctatt
    11521 gtcgatatgg cggatgcggt cggttccacc agtcaactga tcgctgctgc gaaaacattg
    11581 ccacatcagc ggcttatcgt ggcaaccgat cggggcattt tctacaaaat gcagcaggca
    11641 gtgccagata aagagttact ggaagcacca accgcaggtg agggtgcaac ctgccgcagc
    11701 tgcgcgcatt gtccgtggat ggccatgaat ggccttcagt ccatcgcaga ggcattagaa
    11761 caggaaggaa gcaatcacga ggttcatgtt gatgaaaggc tgcgagagag ggcgctggtg
    11821 ccgctcaatc gtatgctgga ttttgcggct acactacgtg gataacgaat aataaggcgt
    11881 aacgttacgc tttgggggaa agatggattt ttttagtgtg cagaatatcc tggtacatat
    11941 accaataggg gcaggcggtt atgatctctc atggatcgaa gcggtaggca cgatcgccgg
    12001 gttgctgtgt attggccttg ccagtctgga gaagatcagc aactacttct ttggcctgat
    12061 caacgtcacc ttgtttggca ttattttctt tcagattcag ctgtatgcca gcctgctatt
    12121 acaggtgttt ttctttgccg cgaatattta cggttggtat gcgtggtcgc gacaaaccag
    12181 tcagaacgag gcggagttga aaattcgctg gttgccattg ccgaaggcac tcagctggtt
    12241 ggcggtttgc gttgtttcga ttggtctgat gacggtattt atcaatccgg tgtttgcatt
    12301 tttgacccgc gtggcagtca tgatcatgca agcattagga ttacaggttg tgatgcctga
    12361 actgcaaccg gacgctttcc cgttctggga ttcatgcatg atggtgttat ctatcgtggc
    12421 aatgattctg atgacgcgta agtatgtgga aaactggctg ttgtgggtga ttattaacgt
    12481 gattagcgtc gttatttttg cacttcaggg cgtttacgcc atgtctctgg agtacatcat
    12541 cctgaccttt attgcgctca acggcagccg gatgtggatc aacagcgcac gtgaaagagg
    12601 ctcacgcgcg ctgtcccatt aatggtgatg atgtgaatgg ccagacaccc cttcattcag
    12661 gtggcagtct ggcccatgac aaggttgata ttccatctga atggtggcgt gctcaatctg
    12721 atagtgatcc atcaggtagt gttggatctg atccaacaag gcatcgtgat cgtgtggcgg
    12781 gatcacctgc acatgcaacg tcatcaccgg cttctcgcct accatccata catgtacatg
    12841 gtgcacattg cggacttccg ggatttcccg gcacatacga cgcttcagtt cagcgatatc
    12901 cagcgatacc ggtgcacctt caagtaattc attcacgcta tctttcaaca gtcgccacgc
    12961 gctacgcaga accagaagcg acaccagtat cgagagaatg gggtcagcag gtgtccagcc
    13021 agtccagata ataatcaacg cggcaataat agccccaacc gaacccagca ggtccccgag
    13081 cacatgcagt gccgctgctc gtacgttgag gtttttctct tcgctgccgt gatgaagtaa
    13141 ccagaaagaa agtatatttg ccagcaaccc agccacggca attgccatca tcatgccgcc
    13201 ctcgaccgga cgcggcgtgc ggaagcgttc tatcgcctcc cagacaatca aaatggtaat
    13261 taccacgagg gctatggcat tcacaaacgc cgcgagcgtg gtcagtctta gccaaccgaa
    13321 agtgtggcga atggtgggag gacgacgtga aaattgcacg gcgagtaggg cgaaaagcag
    13381 ggcggcagta tcggtcaaca tatgacccgc atcggccagc aatgccagag aaccagaaag
    13441 aaaaccacca acgacttcta ccagcataaa cccggcagtc acgccgaaag catacaacaa
    13501 gcgacgagca ttattatctt ctggcaggtg tgaggacgtg tgtgagtgtg agtgcgccat
    13561 gacgagtcat cccttaatta ttctcactta actttatgac atcatactgc ttttagaagt
    13621 gaaaaattaa aagggagaga ctccgctctc ccattattgg ctattttgca gggttactgc
    13681 gtggtaccgt cggttttggt atcgacatca ttattgatgc catcaccggt ttgtaccttt
    13741 ttattgatat ccggacagcg accatctttg cacatggtgt tcttgtgctc ttcatctttg
    13801 gtcattccgt cattgttcat tgaagaacca tccgaatgca gcattgtgcc accagaaccg
    13861 gtatttaccc cgttattgtc gacgttattt ggcgcgacat tttcacgggc gtcaggggct
    13921 acctggcccg catcagctgc ggcgtttgcc tggccgttat tagtttgcgc tccgctatcg
    13981 gcagccagtg cggcaccgct ggcaaggctt agagtggcag tcagaaataa tgtggccagt
    14041 tttgtcattt tcataggatg ctcctgttat ggtcgttatg tcggataacc tcttccaaca
    14101 gtgcatttgc aggtgaatat aaggcattgg tttaagattt cagccaggtt atgaaacgca
    14161 gcagagaatc ttgaaataat taacaaacaa aggagttaca gttagaaatt gtaggagaga
    14221 tctcgttttt cgcgacaatc tggcgttttt cttgctaatt ccaggattaa tccgttcata
    14281 gtgtaaaacc ccgtttacac attctgacgg aagatataga ttggaagtat tgcattcact
    14341 aagataagta tggcaacact ggaacagaca tgaattatca gaacgacgat ttacgcatca
    14401 aagaaatcaa agagttactt cctcctgtcg cattgctgga aaaattcccc gctactgaaa
    14461 atgccgcgaa tacggttgcc catgcccgaa aagcgatcca taagatcctg aaaggtaatg
    14521 atgatcgcct gttggttgtg attggcccat gctcaattca tgatcctgtc gcggcaaaag
    14581 agtatgccac tcgcttgctg gcgctgcgtg aagagctgaa agatgagctg gaaatcgtaa
    14641 tgcgcgtcta ttttgaaaag ccgcgtacca cggtgggctg gaaagggctg attaacgatc
    14701 cgcatatgga taatagcttc cagatcaacg acggtctgcg tatagcccgt aaattgctgc
    14761 ttgatattaa cgacagcggt ctgccagcgg caggtgagtt tctcgatatg atcaccccac
    14821 aatatctcgc tgacctgatg agctggggcg caattggcgc acgtaccacc gaatcgcagg
    14881 tgcaccgcga actggcatca gggctttctt gtccggtcgg cttcaaaaat ggcaccgacg
    14941 gtacgattaa agtggctatc gatgccatta atgccgccgg tgcgccgcac tgcttcctgt
    15001 ccgtaacgaa atgggggcat tcggcgattg tgaataccag cggtaacggc gattgccata
    15061 tcattctgcg cggcggtaaa gagcctaact acagcgcgaa gcacgttgct gaagtgaaag
    15121 aagggctgaa caaagcaggc ctgccagcac aggtgatgat cgatttcagc catgctaact
    15181 cgtccaaaca attcaaaaag cagatggatg tttgtgctga cgtttgccag cagattgccg
    15241 gtggcgaaaa ggccattatt ggcgtgatgg tggaaagcca tctggtggaa ggcaatcaga
    15301 gcctcgagag cggggagccg ctggcctacg gtaagagcat caccgatgcc tgcatcggct
    15361 gggaagatac cgatgctctg ttacgtcaac tggcgaatgc agtaaaagcg cgtcgcgggt
    15421 aaggtttaat tgtcggatgc gccgtcagag tggcgtatcc gatgaatcac cacaggcctg
    15481 ataagtcgcg cagcgtcgca tcaggcaatg tgctccattg ttagcaacaa aaaagccgac
    15541 tcacttgcag tcggctttct cattttaaac gaatgacgtt tacttcgctt taccctggtt
    15601 tgcaaccgcc gctgctttcg ctgcgatctc gtcagcatta cccagataat agcgtttcag
    15661 cggtttgaaa ttctcgtcga actcatacac cagcggcacg ccagtcggga tattaagctc
    15721 aagaatctct tcttcgctca tgttatcaag atatttcacc agcgcacgta aagagttacc
    15781 gtgtgcagcg atgatcacgc gctcaccgct cttcatacgc ggcagaatgg tttcattcca
    15841 gtaagggatc acgcggtcaa tggtcagcgc caggctttcc gtcagcggca gttctttttc
    15901 gctcagtttc gcgtaacgcg gatcgtgacc cggataacgc tcatcatctt tagtcagttc
    15961 cggcggagtc actgcaaaac cacgacgcca ctgtttcacc tgctcgtcgc catacttttc
    16021 agcagtttcc gctttgttca gaccctgcaa cgcaccgtag tgacgttcgt tcagtttcca
    16081 ggatttctca acgggcagcc atgcctgatc cagttcgtcc agcacattcc acagggtatg
    16141 gatagcgcgt ttcagcacag aggtgtaagc aaagtcaaag ctgtaacctt cctctttcag
    16201 cagcttacct gctgcttttg cttcgcttac gcctttctca gacagatcca cgtcgtacca
    16261 accggtgaaa cggttttctt tgttccactg actttcgcca tgacgaacca gaaccagctt
    16321 agttacagcc atatacttac tcctcaaatc attttttaat gataataatt ctcattatat
    16381 tgccgtgacg aagcaacagc aatgcttacg cataaccata gcgaaaatag tgtcgcagtg
    16441 taaggttgtt gtgaatattg agttgcaaat atgtcggtgt ttgctggtga tttgagcaat
    16501 ataaggataa agccctcatt acgagggctt caggtgctac tcagcaataa actgatattc
    16561 cgtcaggctg gaatactctt cgccaggacg caggaagcag tccggttgcg gccattcagg
    16621 gtggtttggg ctgtccggca gaaactcgct ttccagtgcc aggccttgcc agtcggcgta
    16681 aggttcagtt cctcttgatg gcgtgccgcc gaggaagttg ccggagtaga attgcagagc
    16741 cggagcggtg gtgtagacct tcagctgcaa tttttcatct gctgaccaga catgcgccgc
    16801 cactttcttg ccatcgcctt tggcctgtaa caagaatgcg tgatcgtaac ctttcacttt
    16861 gcgctgatcg tcgtcggcaa gaaactcact ggcgatgatt ttggcgctac ggaaatcaaa
    16921 agacgttccg gcgacagatt tcagaccgtc gtgcggaatg ccgccttcat caaccggcag
    16981 atattcgtcc gccagaatct gcaacttgtg attgcgcacg tcagactgct cgccgtcaag
    17041 attgaaatag acgtgattag tcatattcac cgggcaaggt ttatcaactg tggcgcgata
    17101 agtaatagag atacggttat cgtcggtcag acgatattgc accgtcgcgc cgagattacc
    17161 cgggaagccc tgatcgccat catctgaact cagggcaaac agcacctgac gatcgttctg
    17221 gttcacaatc tgccagcgac gtttgtcgaa cccttccggg ccgccgtgca gctggttaac
    17281 gccctgactt ggcgaaagcg tcacggtttc accgtcaaag gtataacggc tattggcgat
    17341 gcggttggca taacgaccaa tagaggcccc cagaaacgca gcctgatcct gatagcattc
    17401 cgggctggca cagccgagca gcgcctcgcg gacgctgcca tcggaaagcg gaatacgggc
    17461 ggaaagtaaa gtcgcacccc agtccatcag cgtgactacc atccctgcgt tgttacgcaa
    17521 agttaacagt cggtacggct gaccatcggg tgccagtgcg ggagtttcgt tcagcactgt
    17581 cctgctcctt gtgatggttt acaaacgtaa aaagtctctt taatacctgt ttttgcttca
    17641 tattgttcag cgacagcttg ctgtacggca ggcaccagct cttccgggat cagcgcgacg
    17701 atacagccgc caaatccgcc gccggtcatg cgtacgccac ctttgtcgcc aatcacagct
    17761 ttgacgattt ctaccagagt gtcaatttgc ggcacggtga tttcgaaatc atcgcgcata
    17821 gaggcatgag attccgccat caactcgccc atacgtttca ggtcgccttg ctccagcgcg
    17881 ctggcagctt caacggtgcg ggcgttttca gtcaggatat gacgcacgcg tttcgccacg
    17941 attgggtcca gctcatgtgc aacagcgttg aactcttcaa tggtgacatc gcgcagagct
    18001 ggctgctgga agaaacgcgc accggtttcg cactgttcac gacgggtgtt gtattcgctg
    18061 ccaaccaggg tacgtttgaa gttactgttg atgatgacga cagccacacc tttcggcatg
    18121 gaaactgctt tagtccccag tgagcggcag tcaatcagca aggcatgatc tttcttgccg
    18181 agtgcggaaa ttagctgatc catgatcccg cagttacagc caacaaactg gttttctgct
    18241 tcctgaccgt taagcgcgat ttgtgcgccg tccagcggca gatgataaag ctgctgcaat
    18301 acggttccga ccgcgacttc cagtgaagcg gaagaactta acccggcacc ctgcggcaca
    18361 ttgccgctga tcaccatgtc cacgccgccg aagctgttgt tacgcagttg cagatgtttc
    18421 accacgccac gaacgtagtt agcccattga tagttttcat gtgcgacaat gggcgcatcg
    18481 agggaaaact cgtcgagctg attttcataa tcggctgcca tcacgcgaac tttacggtca
    18541 tcgcgtggtg cacaactgat cacggtttga taatcaatcg cgcagggcag aacgaaaccg
    18601 tcgttgtagt cggtgtgttc accaatcaaa ttcacgcggc caggcgcctg aatggtgtga
    18661 gtggcagggt agccaaatgc gttggcaaac agagattgtg ttttttcttt cagactcatt
    18721 tcttacactc cgaattcgcg aaaatggata tcgctgactg cgcgcaaacg ctctgctgcc
    18781 tgttctgcgg tcaggtctcg ctgggtctct gccagcattt cataaccaac cataaattta
    18841 cgtacggtgg cggagcgcaa cagaggcgga taaaagtgcg cgtgcagctg ccagtgttga
    18901 ttctcttcgc cattaaatgg tgcgccgtgc cagcccatag agtaggggaa ggaacactgg
    18961 aagaggttgt cataacgact ggtcagcttt ttcaacgcca gcgccaaatc gctgcgctgg
    19021 gcgtcggtca aatcggtgat ccgcaaaacg tgggctttgg gcagcagtag cgtttcgaac
    19081 ggccaggcag cccagtaagg cacaacggct aaccagtgtt cggtttcgac aacggtacgg
    19141 ctaccgtctg ccagctcgcg ctgaacataa tccaccagca ttggtgattt ctgttcggca
    19201 aaatattctt tttgcaggcg gtcttcgcgc tcagcttcgt taggcaggaa gctatttgcc
    19261 caaatctgtc cgtgcggatg cgggttagag cagcccatcg ccgcaccttt gttttcaaag
    19321 acctgcaccc acgggtacgt ttttcccagc tctgcggttt gctcctgcca ggttttgacg
    19381 atttccgtca atgccgcaac gctcagttct ggcaacgttt tactgtgatc cggtgaaaag
    19441 cagatcaccc ggctggtacc gcgcgcgctc tggcaacgca tcaaaggatc gttgctttct
    19501 ggcgcatctg gcgtgtcaga catcaaggcc gcaaagtcat tagtgaaaac gtaagtcctg
    19561 gtgtaatcgg ggtttttatc gcctgtcacc cgcacattac ctgcgcagag gaagcaatct
    19621 ggatcgtgcg caggtaacac ctgtttggct ggcgtttcct gcgccccctg ccaggggcgc
    19681 ttagcgcggt gcggtgaaac cagaatccat tgcccggtga gcgggttgta gcggcgatgt
    19741 ggatgatcaa cgggattaaa ttgcgtcatg gtcgttcctt aatcgggata tccctgtgga
    19801 tggcgtgact gccagtgcca ggtgtcctgc gccatttcat cgagtgtgcg cgttacgcgc
    19861 cagttcagtt cacggtcggc tttgctggcg tccgcccagt aggccggaag gtcgccctcg
    19921 cgacgcggtg caaaatgata attaaccggt ttgccgcagg ctttgctgaa ggcattaacc
    19981 acgtccagca cgctgttgcc tacgccagcg ccgaggttgt agatgtgtac gcctggcttg
    20041 ttcgccagtt tttccatcgc cacgacgtga ccgtccgcca gatccattac gtggatgtaa
    20101 tcgcgtacgc cagtaccatc ttcggtcgga taatcgttac caaaaatcgc cagcgagtcg
    20161 cgacggccta cagcaacctg ggcgatgtat ggcatcaggt tattcggaat gccttgcgga
    20221 tcttcgccca tatcgcccga cggatgcgcg ccaaccgggt tgaagtagcg cagcagggca
    20281 atgctccagt ccggctgggc tttttgcaga tcggtgagga tctgttccac catcagcttg
    20341 cttttgccgt aagggctttg tggtgtgccg gtcgggaagc tttcaacgta tggaattttg
    20401 ggctgatcgc cataaacggt ggcggaggag ctaaaaataa agtttttgac gttagcggcg
    20461 cgcatggcgc taatcaggcg cagagtgccg ttgacattgt tgtcgtaata ttccagcggt
    20521 ttttgtaccg attcgccgac ggctttcagc ccggcgaagt ggatcacggt gtcgatagcg
    20581 tgatcgtgca gtatctcggt catcaacgct tcgttacgaa tatcgccttc aacaaacgtt
    20641 ggatgtttgc cgcctaaacg ctcgataaca ggcagtacgc tgcgcttact gttacagagg
    20701 ttatcaagaa tgatgacatc atgaccgttt tgcagtaatt gcacacaggt atgacttcca
    20761 atgtaaccgc taccaccggt aaccagaact ctcataattc gctccattag gcttatggta
    20821 tgaaataacc atagcataac aaagatgcga aaagtgtgac atggaataaa ttagtggaat
    20881 cgtttacaca agaatttagc cgttttttat gcgcgattaa gtgattataa aacagagggt
    20941 ttatgaatga ttgcgctttt tatctgaaaa aagaagcggt ttcatgcctg catgcgtcga
    21001 accgttggcc ggagagggcg cttaggccgc ctccggcaag gtcagcacta ccgactcaat
    21061 atatttttgt cagcacatag cgatagagtc caccgtccgg cacgaactca aggcgatggg
    21121 taatacaggc aggcgcatct tcagcgtggt gcgaaacaaa caacaattgc gtttcacctt
    21181 cgctaatcag cacatcaaca aaacggcgga taagctggcg attgagcgga tcaagcccct
    21241 gtagtggttc atcgagaata agcaacgtcg gatgtttcac cagtgcgcgg acgatcagcg
    21301 ccagacgctg ctgtccccag gaaagactat ggaacggagc gtcagccgta cgtttatcaa
    21361 tgccgagaat atccagccac tgctgcacca gtttttgctg gcgatccgaa acggcctgat
    21421 aaatgccaat cgaatcaaaa tagccagaaa gaatcacatt acgcacggta gtgctgaccc
    21481 ggtaatccag atgcaaacta ctgctgacgt aaccgatatg ctttttgata tcccagatgg
    21541 tttcgccgct gccgcgacgt cggccgaaaa gcgtcaaatc gttgctgtaa ccttgcggat
    21601 gatcgccagt aatcaggctt aataacgtcg attttcccgc accatttggc ccgacaattt
    21661 gccagtgctc gccaggattc acctgccagc taaggttatt aagaatgggg cgatcgttat
    21721 aagaaaccac gccattattc agcacaatgc gcggttcgtt ggtgggtaag gcgtgacgtg
    21781 ctgaaggttc atccggctcc ggcagttgca caccttcaag ctgttcgcta tgcgccagtt
    21841 gcgcgacgag tgcttgctgg agcagttcct ctttagcgcc cgtttccgct aacgtacaat
    21901 ccgccagcac gccagcaaac tggacaaatt ccgggatctc atcgaagcga ttgagcacca
    21961 gtaccagagt aataccggac tgatgtaacg aggcgagtcg ctcagccagc tgctgacgtg
    22021 aggcaacatc caggccatcg aacggctcat caagaatcaa caagtcaggc tccgacatca
    22081 gcgcctgaca cagcagggtt tttcgcgtct cgccagtgga aaggtattta aagcgtcggt
    22141 cgaggagggc ggtaataccg aactgctgcg ccagttgcat gcaacgcggt gcatccttaa
    22201 cttcatcctg aatgatctca gccgtagtgc gtccggtgtc atcttcgcca gggccgagca
    22261 tatcggtgtt attccgctgc cattcgtcgc tgacgagctt ttgcaattgc tcgaaggaga
    22321 gacgagtgat gtgggaaaac tggctttgcc gttcaccttt caaaagcgga agttcccccg
    22381 ccagcgcacg ggccagcgcc gactttccac ttccattcga accgacaaac gcccaactat
    22441 cacccgcgtt taacgttagc tgaggcaatt gcagcgtttt tgtgtcgcta agacgaaacg
    22501 tgccttgcaa aatttgcaac gatgacattt tatatcccat tttgtgcagc gattactgac
    22561 agggatacgt gtttcataac aaattgtcaa cacgcttagc atagcgtggc gataatcacg
    22621 ctgtcggcat taaagtaggc cgtgacattc tgtccttgct gaagagaagt cgcttcatta
    22681 accggcactg tggcgcacag tgtttgcccg tcgggtagcg ccattaatac ttcgcactgc
    22741 tctgcgccgc gctcaatatg actaataata cccggtaatt ggttgtcggc gttttgtgcg
    22801 accgcttcgt cctgagtaat gcctacccac ggcgctttta gcaatatcaa cacttctttg
    22861 ccttcatcca gccccagacg tgcgccgctt tgtgcggtaa ttgcgacttt caggcgtgtt
    22921 tttccgtcag ccagtaagac atcaacatgc tgttgaacgt catcatgatc gcgggcggtg
    22981 atggtgccga accactggtt acgggcgctg gtttgcagtg aaaaacgtga gatcgcggcc
    23041 agcaggctgt tcagcggcag ggcgtcatcg tcacttaaca catcaaaggc tttttgctgg
    23101 atttgcgcca gtaagtcata gagctgaatc agtcgctgac catagcgggt cagtactgcg
    23161 ccgccgccac ctttaccgcc tgttgcgcgc tcgaccagaa tatgctcact taactgattc
    23221 atctcgttaa tggcatccca ggcgctttta tagctgatac cggcatcttt cgctccctgg
    23281 ctaatggaac cggaaagcgc aatgtgtttt agtagcgaaa tgcggcgcgg gtcggcgaat
    23341 aatttttgtt ggagcttaag ggtgagaagg atttcggcct gcataacaat gtcctggcaa
    23401 aagtcttatt gtgacggaaa acgaacgcca cgcaaagctg accgcacaaa aggggagtgc
    23461 ttttctgtgc ttagcggtta gaatagtctc atgactatat ctggagttga ccatgttaga
    23521 gttattaaaa agtctggtat tcgccgtaat catggtacct gtcgtgatgg ccatcatcct
    23581 gggtctgatt tacggtcttg gtgaagtatt caacatcttt tctggtgttg gtaaaaaaga
    23641 ccagcccgga caaaatcatt gattccctga atgcccgctt agtcgggcat tttctttttc
    23701 tcaacttcct gcttttcctg ccgatatttt ttcttatcta cctcacaaag gttagtaata
    23761 actgctggga aaattccgag ttagtcgtta tattgtcgcc tacataacgt tacattaagg
    23821 ggttaccaat ggctcgtaaa tggttgaact tgtttgccgg ggcggcactc tctttcgctg
    23881 ttgctggcaa tgcactggca gatgaaggga aaatcacggt gttcgccgcc gcatcactga
    23941 ctaacgcaat gcaggacatt gctacgcagt ataaaaaaga gaaaggcgtg gatgtggttt
    24001 cttctttcgc ttcgtcatct actctcgccc gtcagattga agcgggtgcg cctgcggatc
    24061 tgtttatttc tgccgatcag aaatggatgg attatgcagt tgataaaaaa gcgatcgata
    24121 cagctacgcg tcagacactg ctcggcaata gcctggtcgt tgtagcaccg aaagccagcg
    24181 agcagaaaga tttcatcatc gacagcaaaa ctaactggac ttcgctgctg aatggcggtc
    24241 gcctcgcggt tggcgatccg gaacatgtcc ctgctggcat ttatgcaaaa gaagcactgc
    24301 aaaaactggg cgcatgggat acgctctccc cgaaactggc tccggcggaa gatgttcgtg
    24361 gcgcgctggc gttggtcgaa cgcaatgaag cgccgttggg cattgtttac ggttctgacg
    24421 cagttgccag caaaggggta aaagtggttg ccaccttccc ggaagattca cataaaaaag
    24481 tggaatatcc ggttgctgtt gtggaagggc ataacaatgc gacagtgaaa gcattttatg
    24541 attatctgaa gggaccgcag gctgcggaaa tctttaaacg ttacggattt acaaccaagt
    24601 aatgatactg accgatccag aatggcaggc agttttatta agcctgaaag tttcttccct
    24661 ggctgtgctg tttagcctgc cgtttgggat cttttttgcc tggttactgg tgcgttgcac
    24721 gtttccgggc aaagctttgc tcgacagcgt actgcatcta ccgctggtgt taccgcccgt
    24781 ggtcgtcggt tacttattat tagtttcgat gggacggcgc ggatttatcg gtgaacgtct
    24841 gtatgactgg tttggtatta ccttcgcctt tagctggcgc ggcgcggttc tcgctgccgc
    24901 cgtcatgtcg tttccgctaa tggtgcgggc aattcgtctg gcgctggaag gggttgatgt
    24961 caaactggaa caggccgcaa gaacactggg ggccgggcgc tggcgcgttt tctttactat
    25021 cacgttaccg ctgaccttac cgggaattat tgttggtacg gtactggctt ttgctcgttc
    25081 tctcggtgaa tttggcgcaa ccatcacctt tgtgtcgaac attcctggtg aaacgcgaac
    25141 cattccttct gccatgtata ccctgattca gacccccggc ggggaaagtg gcgcagcgag
    25201 actgtgcatt atttctattg cgctggcgat gatctccctg ttgatttcag aatggctggc
    25261 cagaatcagc cgtgaacggg cggggcgcta atcatgctgg aactgaattt ttcccagacc
    25321 ttgggcaacc attgcctgac tattaatgaa acgctgcccg ccaatggcat cactgctatc
    25381 tttggcgtct ccggtgccgg aaaaacttcg ctgattaacg ccatcagtgg actgacgcgc
    25441 ccgcaaaaag ggaggattgt cctcaatggt cgggtactaa atgatgccga aaaaggtatc
    25501 tgcctgacgc cagaaaaacg tcgcgttggc tatgtttttc aggatgcacg gctgttcccg
    25561 cattacaaag tgcgtggcaa tttgcgctac ggcatggcga aaagcatggt cgatcagttc
    25621 gataagctgg tggcgctttt aggcattgaa ccgttgcttg accgtttacc gggcagcctg
    25681 tccggaggcg aaaaacagcg cgtggcgatt ggtcgggctt tgctgacggc tccggaattg
    25741 ctgttgctgg atgaaccgct ggcgtcactg gatattccgc gtaaacgcga actgttgcct
    25801 tatctgcaac gtctgacgcg ggaaatcaac attccgatgt tgtatgtcag ccattcgctg
    25861 gatgagatcc tccatctggc agacagagtg atggtactgg aaaacggtca ggtgaaagcc
    25921 tttggcgcgc tggaagaagt ctggggtagt agcgtgatga atccgtggct gccgaaagag
    25981 caacaaagta gcattctgaa agtgacggta cttgagcatc atccgcatta cgcgatgact
    26041 gcgctggcgc tgggcgatca gcatttgtgg gtcaataagc tggacgaacc gctgcaagct
    26101 gcgctacgta tccgcattca ggcttccgat gtttctctgg ttttacaacc gccgcagcaa
    26161 accagcattc gtaacgtatt gcgggcaaaa gttgttaata gttatgacga caacggccag
    26221 gtggaagtgg agctggaagt cggcggtaaa acgctgtggg cgcgtatcag cccgtgggcc
    26281 agggatgaac tggcgatcaa acctggcctg tggctgtacg cgcaaattaa aagtgtgtcg
    26341 ataaccgcct gattaaatca ggtggctata aatgaactgg gcaatgctgt cggtggtgtt
    26401 atcaccaatc acaatgttgg cgcgcgcttt taccgcgtca tcggcgttgc ccatcgccac
    26461 gcctgtacca gcggcttcca gcatactgat atcattaaag ttatcgccga atgccacgac
    26521 gttttccatc gaccaacctt gcgcctcaac ccatttcgtc aaacgtttac ctttgctgtt
    26581 gccgccgcgt gcaatatcaa cctgatcgtg ccaggaccat tcacactcca gtcccagttc
    26641 atgttcgaca tgcttaccaa aatgctgcaa ttgcggcagg tcatcgtgcg tcagggcgaa
    26701 cttccatacg gcgttaactt gttgcgccgt ttcagccaga gaagcgactt gtgtgaaagt
    26761 cggacgctgt tccggcggca gggtttgcgc ccagttagac gtgcgaatga catgcccggt
    26821 cgggtgctca tagaccattg catcatcgac atacatcaga ccgtgaatgt ggtgttcatt
    26881 cagcatctca atgagttgca gggctttatt aacgggcatt gggtccgctt ccagcacggt
    26941 ttttgcatga taatcataca aataggtgcc attacagcaa atagcaggtg tatccagcgc
    27001 cagcgcctga taaaaaggat gaatagcgac gtgatggcga cctgtgacga tgattaattg
    27061 atagcctgct tcgcgagcgc gggccagggc ttctatcgat gaaggaagca gggtcttttt
    27121 cggggtcaat aaggtgccgt ctaagtcgag agcaatcacg cgtgtggtca tggcgtattc
    27181 cagattaagg ttaagaattt tcgtctgcgc gaatggtaca ccgataccac tatcggacaa
    27241 aattctgcgt tttaattcag cattcaccgc caaaagcgac taattttagc tgttacagtc
    27301 agttgctaaa tgcaaaggag cattcatgaa gcaaacagtt tatatcgcca gccctgagag
    27361 ccagcaaatt cacgtctgga acctgaatca tgaaggcgca ctgacgctga cacaggttgt
    27421 cgatgtgccg gggcaggtgc agccgatggt ggtcagcccg gacaaacgtt atctctatgt
    27481 tggtgttcgc cctgagtttc gcgtcctggc gtatcgtatt gccccggacg atggcgcact
    27541 gacctttgcc gcagagtctg cgctgccggg tagtccgacg catatttcca ccgatcacca
    27601 ggggcagttt gtctttgtag gttcttacaa tgcgggtaac gtgagcgtaa cgcgtctgga
    27661 agatggcctg ccagtgggcg tcgtcgatgt ggtcgagggg ctggacggtt gccattccgc
    27721 caatatctca ccggacaacc gtacgctgtg ggttccggca ttaaagcagg atcgcatttg
    27781 cctgtttacg gtcagcgatg atggtcatct cgtggcgcag gaccctgcgg aagtgaccac
    27841 cgttgaaggg gccggcccgc gtcatatggt attccatcca aacgaacaat atgcgtattg
    27901 cgtcaatgag ttaaacagct cagtggatgt ctgggaactg aaagatccgc acggtaatat
    27961 cgaatgtgtc cagacgctgg atatgatgcc ggaaaacttc tccgacaccc gttgggcggc
    28021 tgatattcat atcaccccgg atggtcgcca tttatacgcc tgcgaccgta ccgccagcct
    28081 gattaccgtt ttcagcgttt cggaagatgg cagcgtgttg agtaaagaag gcttccagcc
    28141 aacggaaacc cagccgcgcg gcttcaatgt tgatcacagc ggcaagtatc tgattgccgc
    28201 cgggcaaaaa tctcaccaca tctcggtata cgaaattgtt ggcgagcagg gactactgca
    28261 tgaaaaaggc cgttatgcgg tcgggcaggg accaatgtgg gtggtggtta acgcacacta
    28321 accgctgatt taaccggcgc agtctctcct gcgccggtgt attaacttat ctcctgtaac
    28381 gcatgtctct ggcgttcgac gatattggtc cacaaattgt ctttatcgtc agtccacaaa
    28441 ttaatcagca aggcaaaaaa gcgttcagct gccggagaaa gcacggcatc tttgcggcga
    28501 ataatcccca atgtccgacg tataacgggt tccaccagtg ggataccaat aatcgaagaa
    28561 tagggcgcat ggggcattgc cagaccagga agcgccgaaa tccccagtcc tgcctccact
    28621 agtcctaatg acgtcgaaag atgacgcact tcgtaaaacc agtccagctt ccagggcttg
    28681 tcggctagct gttgttctat caacaatcgg ttgccgctgg aggaacgtac gccaatcatt
    28741 ttgtaaccca ctaactcctg ccattctaca agctgctttt tggccaatgg atggtcacgc
    28801 cgacaggcca gcacgaatgg ctcgttgacc agtggggtaa aatcaatgga tgaatttgtg
    28861 acgttgttca tgtttatgcc aaagtctgat tcgttacaca gcaccgattc catgcaatta
    28921 ttcgtgcctt gttccagaat ccgcacttta atattgggat acagctcatt aaatttaccg
    28981 attgccagcg gtaaaaaata aaatactgcg gtcggaatac acgctaacgt caccatacca
    29041 cgatgataag cattcatatc acgaatatta aaaagcgttt catcgaattt ctttattaat
    29101 tcccgcgcct ccgggagcaa ccttttccct gcttttgtta acgtaacctt gcgagttgta
    29161 cgctcaaata gttgaatatg taaatcttcc tccatctttt ttattcttcg cgttaatgca
    29221 ggttgcgtaa tattgagtaa tttagcggca ttgttaaatg aactggactc tgccagtatg
    29281 acaaatgcct tcatacttga taattcatgc ttcattatta ctccggaaaa tggaagcgac
    29341 gattttgggt ggctggccgt taaaaatttt aactgcattt agccaactta aattaatgaa
    29401 aaaatgttat taatcgttga gctaaagtca ttagagatgc tttgccctta atgtaaccat
    29461 atcgcaataa gttatgtttt taaattgagg gcattattat gaaaaaaata ccctgcgtga
    29521 tgatgcgagg tggaacctcg aggggcgcgt tcttgttagc ggaacattta cccgaagatc
    29581 aaacgcagcg cgataaaata ttgatggcaa ttatgggttc cggtaacgat ctggaaattg
    29641 acggtattgg cggcggtaat ccgctgacca gtaaagtcgc cattattagc cgttccagcg
    29701 atccgcgtgc tgatgtcgat tatctgtttg ctcaagttat tgtccatgag caacgtgtcg
    29761 ataccacgcc taattgtggc aatatgctgt ctggtgttgg ggcattcgcc attgaaaatg
    29821 gtttgattgc agcgacttca ccagttaccc gcgtacgtat ccgcaacgtc aatactggta
    29881 cgttcatcga agctgatgtg caaacgccaa atggtgttgt cgagtacgag ggtagcgcca
    29941 gaattgacgg cgtaccgggt actgccgcac cggttgcgct cactttcctg aatgccgccg
    30001 gaaccaaaac cggaaaagtc ttcccgactg ataatcagat tgattatttt gacgatgtcc
    30061 cggtgacctg tatcgatatg gcgatgccag tcgtcattat tccggctgaa tatctgggaa
    30121 aaacaggtta tgaattaccg gcggaactgg atgccgacaa agcattatta gcacgcattg
    30181 aatctatccg tctacaagcg ggtaaagcaa tgggcttagg tgatgtcagt aatatggtta
    30241 tccctaaacc tgtgcttatt tctccagcgc agaaaggcgg ggcaattaat gtacgttatt
    30301 ttatgccgca ttcttgccat cgcgcgctgg cgataaccgg tgctattgct atttccagta
    30361 gttgtgcatt ggaaggcacc gtcacccgac aaatcgtccc ttctgtagga tacggcaata
    30421 tcaatattga acaccccagt ggtgcgctcg acgttcattt aagtaatgaa ggtcaggatg
    30481 ccacgacgtt acgcgcatct gttattcgga cgaccagaaa aatattttcc ggtgaagttt
    30541 atcttccctg aaaaaattcg ttgtcaggat aaggacaatc aataaaggac ttctgtatga
    30601 gtcatacaga aagaacagga ttttaaatga ataagaaatc gttatggaag ctaattctga
    30661 tattagcgat cccatgtatt attggtttta tgccagctcc ggcaggatta agcgaactgg
    30721 cgtgggtgct ttttggtatt tacctggcgg ccattgtggg tctggttatc aagcctttcc
    30781 cggaacctgt cgtactgtta attgccgttg ctgcctcaat ggtggtggtc ggtaacttat
    30841 ccgacggtgc gtttaagacc accgccgtat taagcggtta ctcttcaggt actacctggc
    30901 tggtgttctc ggcgtttacc ttaagcgccg catttgtgac caccggttta ggtaaacgta
    30961 ttgcctatct gctgattggt aaaatcggta acaccacgct gggtctgggt tacgttacgg
    31021 tattcctcga tctggtactg gctccggcaa caccgtctaa caccgcgcgt gcgggcggca
    31081 ttgtgttacc gatcatcaac agcgtggcgg tggctttggg gtccgaaccg gaaaaaagtc
    31141 cgcgtcgtgt cggacattac ctgatgatgt ccatttacat ggtcaccaaa accaccagct
    31201 atatgttctt taccgcaatg gcggggaaca ttctggcgct gaaaatgatc aacgacattc
    31261 tgcacctgca aattagctgg ggtggatggg cgctggccgc cggattgccg ggcatcatta
    31321 tgctgctggt caccccgctg gtaatttaca ccatgtatcc accagaaatt aaaaaggtgg
    31381 ataacaaaac catcgctaaa gcgggccttg ccgaactggg accgatgaaa atccgcgaaa
    31441 aaatgctgct cggtgtcttt gtgctggcgc tactgggctg gattttcagt aagtctctgg
    31501 gggttgatga atccactgtg gcaatcgttg ttatggcgac catgctgctg ctgggtatcg
    31561 ttacctggga agacgtggtt aaaaataaag gcggctggaa taccttaatc tggtacggcg
    31621 gtattatcgg attaagctcc ttattatcga aagttaaatt cttcgaatgg ttagctgaag
    31681 tctttaaaaa taacctggca tttgatggtc acggtaacgt tgctttcttc gttattattt
    31741 tcctcagcat tatcgtgcgt tatttcttcg cttccggtag tgcctatatc gttgctatgt
    31801 taccggtatt tgccatgctg gcgaacgtct ccggcgcacc gttaatgtta accgcgctgg
    31861 cactgttgtt ctccaactcc tatggcggca tggttactca ctatggcggc gcggcaggtc
    31921 cggtcatctt tggcgtgggt tataacgata ttaaatcctg gtggttggtc ggtgcggtac
    31981 tgacgatatt aaccttcctg gtgcatatca ccctcggcgt gtggtggtgg aatatgctga
    32041 tcggctggaa catgctgtaa atattctcgt catacttcaa gttgcatgtg ctgcgtctgc
    32101 gttcgctcac cccagtcact tacttatgta agctcctggg gattcactcg cttgtcgcct
    32161 tcctgcaact caaattattt agagtatatc catttattat ctttctgcgc acttcacggt
    32221 gcgcagatat ctggagcatt tgatgatcaa gttatctgaa aaaggcgtgt ttctcgccag
    32281 taataacgaa ataattgctg aagaacattt caccggcgaa attaaaaaag aagaagccaa
    32341 aaaaggcact attgcctggt ctattctctc ttcgcataat acgtccggaa atatggataa
    32401 acttaaaatt aagtttgatt cattagcctc tcacgatatt acctttgttg gtattgtaca
    32461 gaccgctaaa gcgtccggta tggaacgttt cccgctgccg tatgtgctga ccaactgcca
    32521 taactcactc tgcgccgtcg gcggcaccat taacggtgat gaccatgttt ttggtttatc
    32581 ggcagctcag cgttatggcg gtatttttgt gcctccgcat attgcggtca tccatcaata
    32641 tatgcgtgag atgatggcag gcggcggcaa aatgatcctc gggtcagaca gccacacccg
    32701 ttacggtgca ttagggacaa tggcagtcgg tgagggcggt ggtgagttgg taaaacagct
    32761 gcttaatgac acctgggata tcgactatcc gggagttgtt gcggtgcatc tgaccggaaa
    32821 accagcgccg tatgtggggc cgcaggatgt ggcgctggct atcattggcg cggtgttcaa
    32881 aaacggttac gtcaaaaaca aagtcatgga gttcgttgga ccgggcgtta gcgcgctctc
    32941 taccgatttc cgtaacagcg ttgacgtgat gaccacggaa accacctgtt taagctccgt
    33001 ctggcaaact gatgaagaag tgcataactg gctggcgctg cacggtcgcg gccaggatta
    33061 ctgccagctt aaccctcaac cgatggcgta ctacgatggc tgcatcagcg ttgatttaag
    33121 cgccatcaaa ccaatgattg cgctgccgtt ccacccgagc aacgtgtatg aaatcgacac
    33181 actgaaccag aacctgaccg acattctgcg tgagattgaa attgagtccg aacgcgtggc
    33241 gcacggtaaa gccaaactct cgctgctgga taaagtggaa aatggtcgcc tgaaagtgca
    33301 gcaggggatt atcgcgggct gttctggcgg taactacgaa aacgtcatcg cggcggcgaa
    33361 tgcactgcgc ggtcaatcct gtggcaatga caccttctcg ctggcagttt acccgtcatc
    33421 acagccggtg tttatggatc tcgccaaaaa aggtgtggta gcagatttga ttggcgcagg
    33481 cgcaatcatc agaaccgcgt tctgcggccc atgctttggc gcgggcgata cgccaatcaa
    33541 caacggatta agtattcgcc acaccacgcg taacttcccg aaccgcgaag gctctaagcc
    33601 agctaatggg cagatgtcag cggtggcgtt gatggacgct cgttctatcg ctgcgactgc
    33661 ggcaaacggt ggctatttaa cctctgccag cgaacttgat tgctgggaca acgtgccgga
    33721 gtacgccttc gatgtaacgc cgtataaaaa ccgtgtttat cagggctttg tgaaaggggc
    33781 aactcagcaa ccgctgattt acggaccgaa cattaaagac tggccggaat tgggtgcgct
    33841 gactgacaat atcgtcctga aagtgtgctc gaagatcctc gacgaagtga ccaccaccga
    33901 cgaactgatt ccttccggtg aaacctcttc ttatcgttca aatccgattg gtctggcgga
    33961 gtttaccctg tcacgccgcg atcccggtta tgttggcaga agtaaagcga ctgctgagct
    34021 ggaaaatcag cgtctggcgg ggaatgtcag cgagctgaca gaggtgtttg cgcgcattaa
    34081 gcagattgct ggtcaggagc atattgatcc gctgcaaact gaaattggca gcatggtata
    34141 tgcggtgaaa ccaggcgatg gttctgcgcg tgaacaggcg gcgagctgcc agcgtgtgat
    34201 tggcggtctg gcgaatattg ccgaagagta cgcgactaaa cgctaccgtt ctaacgtcat
    34261 caactggggg atgttaccgc tgcagatggc ggaagtgcca acctttgaag tgggggatta
    34321 catttacatc cctggcatta aagcggcgct ggataatccg ggtacgacgt ttaaaggtta
    34381 tgtgatccat gaagatgcgc cggtaacgga aattacgctc tatatggaaa gtctgactgc
    34441 tgaagagcgc gagattatca aggcgggtag tttgattaac ttcaataaaa accgtcagat
    34501 gtaaaaagcg ccatgtgaat gtaggtcgca ttcggcactt attgtcggat gcgatgcttg
    34561 cgcatcttat ccgacctacg aatcgcatcg aatctgtagg ccggataagg cgtttacgcc
    34621 gcatccggca aatagttaat agctcttact tcttcgcctc tgcaaccact ttactaccca
    34681 cgccgcggtt attgtattcc cacatgcggt tgtagttagt gtcattcaga ttgcgctgta
    34741 tttcgtcgtt atcatctacg ctgccggtat tacccgcaaa cggacgatta gagatcaccg
    34801 catcggccca cggtttagcc gtgttaaaac cttcgttgat ggcgctatca cggatcacca
    34861 cctgaccgtt ggtattggca tcaacatcca gcgagcggcc cagttgcgcc acaccatcac
    34921 cgaaagcatt gaaacggctg tttacggcga ggaaaccgta gtaaatgttg gacagcgtag
    34981 ccggtgcaaa cacatacgct tcttgctgag tacgtgagtt caccacgcgg aattcggtgt
    35041 tatcgaacac cactgcgccg cgaccagaaa cgatatccac atccccttca atgtagctgt
    35101 tggtcaccag cgtacgcggc tgacggttgg tttccagacg gttctgcaca ccgctgttgg
    35161 tgacaaagaa ggtgttctga cgaccgagaa tgttaacgtt gttaatctgt acctggtcac
    35221 catcagtacg cagtgccacc gccggatggt tacctgcatc tacgctatcg cccagcgtgt
    35281 tttcgatggt cagattttgc agttgcaggc cattgttttg tgaccagaag accgcagagc
    35341 agagaacacc gatactgtcg ctgcgtttgc tctggcagct atcgtacata taccacgctg
    35401 gtttacctgg catatatttg ccgcgcgggt tgacgtcgtg acgccagtcg gcagggctca
    35461 tgcccccatc aagggaaagc ccaatcttca catcaatcgg tttttcacct gtaccgtaca
    35521 gagtaattcc acccggagca gcagggacat acaccgttcc ctgatactca ccaggcatca
    35581 cggcaatata ctggcgcttg ttagtgcgct tgataattgc cgcatctacc gccgcctgaa
    35641 tcgtggtatg cgttacacct tgagtacccg ccgggccgac aacaaagtca ggttgcgcag
    35701 gcagggtaat cggggaagga ttccacgctg cagcacctgg tgtcagggat gcaaaatagt
    35761 gttgagcatc gaaattctgc gcttcttttg ccgacagaat cgggcgagaa gaggtaccag
    35821 gcgcggtttg atcagaagga cgttgatcgg gtggtgttga gctacaggcg gtcagcgtca
    35881 cgccaaaagc caatgccagc gccagacggg aaactgaaaa tgtgttcaca ggttgctccg
    35941 ggctatgaaa tagaaaaatg aatccgttga agcctgcttt tttatactaa cttgagcgaa
    36001 acgggaaggt aaaaagacaa aaagttgttt ttaatacctt taagtgatac cagatggcat
    36061 tgcgccatct ggcagagtga ttaactaaac atcgcagtaa tcgaggcgct tgccagagag
    36121 tggaaatgaa cgttaaaccc gaccatcgcg ccgctggcac cttcatcgac atcaatacgt
    36181 tctatatcca gcgcgtgaac ggtaaaaatg tagcgatgag tttcgccttt cggcggtgct
    36241 gcgccatcgt acccggtttt accaaagtcg gtacgcgtct gcaaaacgcc gtctggcatt
    36301 gctaccagac cagagccaaa cccttgcggt aatacgcggg tatcagcggg taagttaaca
    36361 actacccagt gccaccagcc ggagccggtt ggcgcatccg ggtcgtagca ggtgacaaca
    36421 aaacttttcg ttcccgcagg aacatcatcc cacgccagat gcggtgaaat attatcgcca
    36481 tcgtaaccca tgccgttaaa gacatgacga tgcggcaatt tatcgccatc gcgcagatcg
    36541 ttactgatga gtttcatgaa ccctcctttc ttgtttgcag aaagtgtagc cagaaaccct
    36601 cacgcggact tctcgttatt ggcaaaaaaa tgtttcatcc tgtaccgcgc ggttaaccgc
    36661 tgcggtcaga cgctgcaact gttgcgggag aataatatag ggcggcatca ggtaaatcag
    36721 tttgccaaaa ggccggatcc agacaccctg ttcgacaaag aatttttgca gcgccgccat
    36781 attcaccgga cgagtggttt cgactacgcc gattgccccc agcacgcgca catcggcaac
    36841 catttcggca tcacgggcgg gggcaagttg ctcgcgcagc tgtacttcaa tagccgccac
    36901 ctgttgctgc cagtcgccag attcgagaat cgccaggctg gcgtttgctg ccgcgcaggc
    36961 cagcggattg cccataaaag ttggcccatg cataaagcaa ccggcttcgc cgttactgat
    37021 ggtttccgca acctcgcgcg tggtgagcgt ggcggaaagg gtcattgtgc cgccggttaa
    37081 ggctttaccg aggcacaaaa tgtccggcgc gatttctgca tgttcacagg caaacagttt
    37141 gccggtacga ccaaatccgg tggcgatctc gtcggcaatc agcaagatac cttcgcgatc
    37201 gcacattttg cggattcgtt ttaaccattc cggatggtac atgcgcatcc cgcctgcgcc
    37261 ctggacaatc ggttcaatga tcaccgccgc gatttcatga cgatgcgccg ccatcaggcg
    37321 ggcaaagcca accatatcac gttcatccca ttcaccatcc atgcggcttt gcggggcggg
    37381 agcaaacaag ttttctggca gatagccttt ccacaggctg tgcattgagt tgtccggatc
    37441 gcacaccgac atcgcgccaa aggtatcgcc atgataacca ttgcggaagg tcagaaaacg
    37501 gtggcgcgct tcgcctttgg cctgccagta ctgcaacgcc attttcatcg ccacttccac
    37561 cgctacggag ccggagtccg cgagaaaaac gcattccagc ggttgcggcg tcattgccac
    37621 cagtttgcgg catagctcga tggcgggcgc atgggtgata ccgccaaaca tcacatgcga
    37681 catagcatca atttgcgact tcatcgccgc attaagctgc gggtgattat agccgtggat
    37741 cgccgcccac caggacgaca taccgtcaac caggcgtctg ccgtcagaca aaattagctc
    37801 gcaaccttcg gcgctcgcga ccggataaac cggcagaggg gaggtcatgg atgtgtatgg
    37861 gtgccagata tggcgttggt caaaggcaag atcgtccgtt gtcataatcg acttgtaaac
    37921 caaattgaaa agatttaggt ttacaagtct acaccgaatt aacaacaaaa aacacgtttt
    37981 ggagaagccc catggctcac cgcccacgct ggacattgtc gcaagtcaca gaattatttg
    38041 aaaaaccgtt gctggatctg ctgtttgaag cgcagcaggt gcatcgtcag catttcgatc
    38101 cacgtcaggt gcaggtcagc acgttgctgt cgattaagac cggagcttgt ccggaagatt
    38161 gcaaatactg cccgcaaagc tcgcgctaca aaaccgggct ggaagccgag cggttgatgg
    38221 aagttgaaca ggtgctggag tcggcgcgca aagcgaaagc ggcaggatcg acgcgcttct
    38281 gtatgggcgc ggcgtggaag aatccccacg aacgcgatat gccgtacctg gaacaaatgg
    38341 tgcagggggt aaaagcgatg gggctggagg cgtgtatgac gctgggcacg ttgagtgaat
    38401 ctcaggcgca gcgcctcgcg aacgccgggc tggattacta caaccacaac ctcgacacct
    38461 cgccggagtt ttacggcaat atcatcacca cccgcactta tcaggaacgc ctcgatacgc
    38521 tggaaaaagt gcgcgatgcc gggatcaaag tctgttctgg cggcattgtg ggcttaggcg
    38581 aaacggtaaa agatcgcgcc ggattattgc tgcaactggc aaacctgccg acgccgccgg
    38641 aaagcgtacc aatcaacatg ctggtgaagg tgaaaggcac gccgctggcg gataacgatg
    38701 atgtcgatgc ctttgatttt attcgcacca ttgcggtcgc gcggatcatg atgccgacct
    38761 cttacgtgcg cctttctgcc ggacgcgagc agatgaacga acagactcag gcgatgtgct
    38821 ttatggcagg cgcaaactcg attttctacg gttgcaaact gctgaccacg ccgaatccgg
    38881 aagaagataa agacctgcaa ctgttccgca aactggggct aaatccgcag caaactgccg
    38941 tgctggcagg ggataacgaa caacagcaac gtcttgaaca ggcgctgatg accccggaca
    39001 ccgacgaata ttacaacgcg gcagcattat gagctggcag gagaaaatca acgcggcgct
    39061 cgatgcgcgg cgtgctgccg atgccctgcg tcgccgttat ccagtggcgc aaggagccgg
    39121 acgctggctg gtggcggatg atcgccagta tctgaacttt tccagtaacg attatttagg
    39181 tttaagccat catccgcaaa ttatccgtgc ctggcagcag ggggcggagc aatttggcat
    39241 cggtagcggc ggttccggtc acgtcagcgg ttatagcgtt gcgcatcagg cgctggaaga
    39301 agaactggcc gagtggctgg gctattcgcg ggcactgcta tttatctctg gttttgccgc
    39361 taatcaggcg gtcattgccg cgatgatggc aaaagaggac cgcattgtcg ctgaccggct
    39421 tagccatgcc tcattgctgg aggctgccag tttaagcccg tcgcagcttc gccgttttgt
    39481 tcataacgat gtcactcatc tggcgcgact gcttgcttcc ccctgtccgg ggcagcaact
    39541 ggtggtgaca gaaggcgtgt tcagcatgga cggcgatatt gcgccactgg cggaaatcca
    39601 gcaggtaacg caacagcaca atggctggtt gatggtcgat gatgcccacg gcacgggcgt
    39661 tatcggggag caggggcgcg gcagctgctg gctgcaaaag gtaaaaccag aattgctggt
    39721 ggtgactttt ggcaaaggat ttggcgtcag tggggctgcg gtgctttgct ccagtacggt
    39781 ggcggattat ctgctgcaat tcgcccgcca ccttatctac agcaccagta tgccgcccgc
    39841 tcaggcgcag gcattacgtg cgtcactggc ggtcattcgc cgtgatgagg gggatgcacg
    39901 gcgcgaaaaa ctggtgtcac tcattgcgcg ttttcgtgcc ggagtacagg atttgccgtt
    39961 tacgctggct gattcatgca gcgccatcca gccattgatc gtcggtgata acagccgtgc
    40021 gttacaactg gcagaaaaac tgcgccagca aggctgctgg gtcacggcga ttcgcccgcc
    40081 aaccgtaccc gctggtactg cgcgactgcg cttaacgcta accgcagcgc atgaaatgca
    40141 ggatatcgac cgtctgctgg aggtgctgca tggcaacggt taataaacaa gccattgcag
    40201 cggcatttgg tcgggcagcc gcactctatg agcaacacgc agatctacag cgccagagtg
    40261 ctgacgtctt actggcaatg ctcccacagc gtaaatacac ccacgtactg gacgcgggtt
    40321 gtggacctgg ctggatgagc cgccactggc gggaacgtca cgcgcaggtg acggccttag
    40381 atctctcgcc gccaatgctt gttcaggcac gccagaagga tgccgcagac cattatctgg
    40441 cgggagatat cgaatccctg ccgttagcga ctgcgacgtt cgatcttgca tggagcaatc
    40501 tcgcagtgca gtggtgcggt aatttatcca cggcactccg cgagctgtat cgggtggtgc
    40561 gccccggagg cgtggtggcg tttaccacgc tggtgcaggg atcgttaccc gaactgcatc
    40621 aggcgtggca ggcggtggac gagcgtccgc atgctaatcg ctttttaccg ccagatgaaa
    40681 tcgaacagtc actgaacggc gtgcattatc aacatcatat tcagcccatc acgctgtggt
    40741 ttgatgatgc gctcagtgcc atgcgttcgc tgaaaggcat tggtgccacg catcttcatg
    40801 aagggcgcga cccgcgaata ttaacgcgtt cgcagttgca gcgattgcaa ctggcttggc
    40861 cgcaacaaca ggggcgatat cctctgacgt atcatctttt tttgggagtg attgctcgtg
    40921 agtaaacgtt attttgtcac cggaacggat accgaagtgg ggaaaaccgt cgccagttgt
    40981 gcacttttac aagccgcaaa ggcagtaggc taccggacgg caggttataa accggtcgcc
    41041 tctggcagtg aaaagacccc ggaaggctta cgtaatagcg acgcgctggc gttacagcgc
    41101 aacagcagcc tgcagctgga ttacgcaacg gtaaatcctt acaccttcgc agaacccacc
    41161 tcgccgcaca tcatcagcgc gcaagagggc aggccgatag aatcattggt aatgagcgcc
    41221 ggattacgcg cgcttgaaca acaggctgac tgggtgttag tggaaggcgc tggcggctgg
    41281 tttacgccgc tttctgacac tttcactttt gcagattggg taacacagga acaactgccg
    41341 gtaatactgg tagttggtgt gaaacttggc tgtattaatc acgcgatgtt aactgcacag
    41401 gcaatacaac acgccggact gactctggcg ggttgggtgg cgaatgatgt cacgcctcct
    41461 ggaaaacgtc acgctgaata tatgaccacg ctcacccgca tgattcccgc gccgctgctg
    41521 ggagagatcc cctggcttgc agaaaatcca gaaaatgcgg caactggaaa gtacataaac
    41581 cttgcct
//
LOCUS       DAPGUL010000031        40897 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.031, whole genome shotgun sequence.
ACCESSION   DAPGUL010000031 DAPGUL010000000
VERSION     DAPGUL010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 40897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40897
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.031"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(157..1014)
                     /gene="murI"
                     /locus_tag="RHX21_001802"
     CDS             complement(157..1014)
                     /gene="murI"
                     /locus_tag="RHX21_001802"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312925.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HDV1986992.1"
                     /translation="MATKLQDGNTPCLAATPSEPRPTVLVFDSGVGGLSVYDEIRHLL
                     PDLHYIYAFDNVAFPYGEKSEAFIVERVVAIVTAVQERYPLALAVVACNTASTVSLPA
                     LREKFDFPVVGVVPAIKPAARLTANGIVGLLATRGTVKRSYTHELIARFANECQIEML
                     GSAEMVELAEAKLHGEDVSLDALKRILRPWLRMKEPPDTVVLGCTHFPLLQEELLQVL
                     PEGTRLVDSGAAIARRTAWLLEHEAPDAKSADANIAFCMAMTPEAEQLLPVLQRYGFE
                     TLEKLAVLG"
     gene            complement(959..2803)
                     /gene="btuB"
                     /locus_tag="RHX21_001803"
     CDS             complement(959..2803)
                     /gene="btuB"
                     /locus_tag="RHX21_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent vitamin B12 receptor BtuB"
                     /protein_id="HDV1986993.1"
                     /translation="MIKKASLLTACSVTAFSAWAQDTSPDTLVVTANRFEQPRSTVLA
                     PTTVVTRQDIDRWQSTSVNDVLRRLPGVDITQNGGSGQLSSIFIRGTNASHVLVLIDG
                     VRLNLAGVSGSADLSQFPIALVQRVEYIRGPRSAVYGSDAIGGVVNIITTRDEPGTEI
                     SAGWGSNSYQNYDVSTQQQLGDKTRVTLLGDYAYTHGYDVVAYGNTGTQAQPDKDGFL
                     SKTLYGALEHNFTDAWSGFVRGYGYDNRTNYDAYYSPGSPLVDTRKLYSQSWDAGLRY
                     NGELIKSQLITSYSHSKDYNYDPHYGRYDSSATLDEMKQYTVQWANNVIVGHGSIGAG
                     VDWQKQTTTPGTGYVEDGYDQRNTGIYLTGLQQVGDFTFEGAARSDDNSQFGRHGTWQ
                     TSAGWEFIEGYRFIASYGTSYKAPNLGQLYGFYGNPNLDPEKSKQWEGAFEGLTAGVN
                     WRISGYRNDVSDLIDYDDHTLKYYNEGKARIKGVEATANFDTGPLTHTVSYDYVDARN
                     AITDTPLLRRAKQQVKYQLDWQLYDFDWGITYQYLGTRYDKDYSSYPYQTVKMGGVSL
                     WDLAVAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF"
     regulatory      complement(2868..3058)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            3172..4272
                     /gene="trmA"
                     /locus_tag="RHX21_001804"
     CDS             3172..4272
                     /gene="trmA"
                     /locus_tag="RHX21_001804"
                     /EC_number="2.1.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (uridine(54)-C5)-methyltransferase TrmA"
                     /protein_id="HDV1986994.1"
                     /translation="MTPEHLPTEQYEAQLAEKVVRLQSMMAPFSDLVPEVFRSPVSHY
                     RMRAEFRIWHDGDDLYHIIFDQQTKSRIRVDSFPAASELINQLMTAMIAGVRNNPVLR
                     HKLFQIDYLTTLSNQAVVSLLYHKKLDDEWRQEAEALRDALRAQNLNVHLIGRATKTK
                     IELDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALDVTKGSKGDLLELY
                     CGNGNFSLALARNFDRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNG
                     VREFNRLQGIDLKSYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLE
                     TLSQTHKVERLALFDQFPYTHHMECGVLLTAK"
     gene            complement(4312..4602)
                     /locus_tag="RHX21_001805"
                     /pseudo
     CDS             complement(4312..4602)
                     /locus_tag="RHX21_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312922.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YijD family membrane protein"
     gene            4660..5357
                     /locus_tag="RHX21_001806"
                     /pseudo
     CDS             4660..5357
                     /locus_tag="RHX21_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
     gene            complement(5367..5459)
                     /locus_tag="RHX21_001807"
                     /pseudo
     CDS             complement(5367..5459)
                     /locus_tag="RHX21_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312922.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1422 family protein"
     gene            complement(5459..6109)
                     /gene="fabR"
                     /locus_tag="RHX21_001808"
     CDS             complement(5459..6109)
                     /gene="fabR"
                     /locus_tag="RHX21_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor FabR"
                     /protein_id="HDV1986995.1"
                     /translation="MMGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGI
                     APTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGN
                     NPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVT
                     IVFSAGAEALDVGVEQRRQLEERLVLQLRMISKGAYYWYRREQEKTAIIPGNVKDE"
     gene            6440..7840
                     /gene="sthA"
                     /locus_tag="RHX21_001809"
     CDS             6440..7840
                     /gene="sthA"
                     /locus_tag="RHX21_001809"
                     /EC_number="1.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418397.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Si-specific NAD(P)(+) transhydrogenase"
                     /protein_id="HDV1986996.1"
                     /translation="MPHSYDYDAIVIGSGPGGEGAAMGLVKQGARVAVIERYQNVGGG
                     CTHWGTIPSKALRHAVSRIIEFNQNPLYSDHSRLLRSSFADILNHADNVINQQTRMRQ
                     GFYERNHCEILQGNARFVDEHTLALDCPDGSVETLTAEKFIIACGSRPYHPTDVDFTH
                     PRIYDSDSILSMHHEPRHVLIYGAGVIGCEYASIFRGMDVKVDLINTRDRLLAFLDQE
                     MSDSLSYHFWNSGVVIRHNEEYEKIEGCDDGVIMHLKSGKKLKADCLLYANGRTGNTD
                     SLALQNIGLETDSRGQLKVNSMYQTAQPHVYAVGDVIGYPSLASAAYDQGRIAAQALV
                     KGEATAHLIEDIPTGIYTIPEISSVGKTEQQLTAMKVPYEVGRAQFKHLARAQIVGMN
                     VGTLKILFHRETKEILGIHCFGERAAEIIHIGQAIMEQKGGGNTIEYFVNTTFNYPTM
                     AEAYRVAALNGLNRLF"
     gene            complement(7823..8740)
                     /gene="oxyR"
                     /locus_tag="RHX21_001810"
     CDS             complement(7823..8740)
                     /gene="oxyR"
                     /locus_tag="RHX21_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator OxyR"
                     /protein_id="HDV1986997.1"
                     /translation="MNIRDLEYLVALAEHRHFRRAADSCHVSQPTLSGQIRKLEDELG
                     VMLLERTSRKVLFTQAGMLLVDQARTVLREVKVLKEMASQQGETMSGPLHIGLIPTVG
                     PYLLPHIIPMLHQTFPKLEMYLHEAQTHQLLAQLDSGKLDCVILALVKESEAFIEVPL
                     FDEPMLLAIYEDHPWANRECVPMADLAGEKLLMLEDGHCLRDQAMGFCFEAGADEDTH
                     FRATSLETLRNMVAAGSGITLLPALAVPPERKRDGVVYLPCIKPEPRRTIGLVYRPGS
                     PLRSRYEQLAEAIRARMDGHFDKVLKQAV"
     gene            complement(9007..10380)
                     /gene="argH"
                     /locus_tag="RHX21_001811"
     CDS             complement(9007..10380)
                     /gene="argH"
                     /locus_tag="RHX21_001811"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HDV1986998.1"
                     /translation="MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKAL
                     VTVGVLTAEEQAQLEEALNVLLEDVRARPQQILESDAEDIHSWVEGKLIDKVGQLGKK
                     LHTGRSRNDQVATDLKLWCKDTVSELLTANRQLQSALVETAQNNQDAVMPGYTHLQRA
                     QPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEIDREQLAGWLGF
                     ASATRNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFNTGEAGFVELSDRVTSG
                     SSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDT
                     WLDCLHMAALVLDGIQVKRPRCQEAAQQGYANATELADYLVAKGVPFREAHHIVGEAV
                     VEAIRQGKPLEDLPLSELQKFSQVIDEDVYPILSLQSCLDKRAAKGGVSPQQVAQAIA
                     FAQARLG"
     gene            complement(10441..11217)
                     /gene="argB"
                     /locus_tag="RHX21_001812"
     CDS             complement(10441..11217)
                     /gene="argB"
                     /locus_tag="RHX21_001812"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418394.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HDV1986999.1"
                     /translation="MMNPLIIKLGGVLLDSEEALERLFSALVNYRESHQRPLVIVHGG
                     GCVVDELMKGLNLPVKKKNGLRVTPADQIDIITGALAGTANKTLLAWAKKHQIAAVGL
                     FLGDGDSVKVTQLDEELGHVGLAQPGSPKLINSLLENGYLPVVSSIGVTDEGQLMNVN
                     ADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAAKAEQLIEQGIITDGMIVKV
                     NAALDAARTLGRPVDIASWRHAEQLPALFNGMPMGTRILA"
     gene            complement(11225..12229)
                     /gene="argC"
                     /locus_tag="RHX21_001813"
     CDS             complement(11225..12229)
                     /gene="argC"
                     /locus_tag="RHX21_001813"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HDV1987000.1"
                     /translation="MLNTLIVGASGYAGAELVTYVNRHPHMNITALTVSAQSNDAGKL
                     ISDLHPQLKGIVDLPLQPMSDISEFSPGVDVVFLATAHEVSHDLAPQFLEAGCVVFDL
                     SGAFRVNDATFYEKYYGFTHQYPELLEQAAYGLAEWCGNKLKEANLIAVPGCYPTAAQ
                     LALKPLIDADLLDLNQWPVINATSGVSGAGRKAAISNSFCEVSLQPYGVFTHRHQPEI
                     ATHLGADVIFTPHLGNFPRGILETITCRLKSGVTQAQVAQVLQQAYAHKPLVRLYDKG
                     VPALKNVVGLPFCDIGFAVQGEHLIIVATEDNLLKGAAAQAVQCANIRFGYAETQSLI
                     "
     gene            12383..13534
                     /gene="argE"
                     /locus_tag="RHX21_001814"
     CDS             12383..13534
                     /gene="argE"
                     /locus_tag="RHX21_001814"
                     /EC_number="3.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylornithine deacetylase"
                     /protein_id="HDV1987001.1"
                     /translation="MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFK
                     DLGFNVEVQPVPGTRNKFNMLASIGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHD
                     GKLYGLGTADMKGFFAFILDALRDVDVTKLKKPLYILATADEETSMAGARYFAETTAL
                     RPDCAIIGEPTSLQPVRAHKGHISNAIRIQGQSGHSSDPARGVNAIELMHDAIGHILQ
                     LRDNLKERYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNELNG
                     LLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKLLGAKTEVVNYCTEA
                     PFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH"
     gene            14132..16783
                     /gene="ppc"
                     /locus_tag="RHX21_001815"
     CDS             14132..16783
                     /gene="ppc"
                     /locus_tag="RHX21_001815"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004203687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HDV1987002.1"
                     /translation="MNEQYSALRSNVSMLGKVLGETIKDALGEHILERVETIRKLSKS
                     SRAGNDANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPE
                     VIARTLRKLKNQPELSEDTIKKAVESLSLELVLTAHPTEITRRTLIHKMVEVNACLKQ
                     LDNKDIADYEHNQLMRRLRQLIAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWQGVP
                     NYLRELNEQLEENLGYKLPVEFVPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKAT
                     DLFLKDIQVLVSELSMVEATPELLALVGEEGAAEPYRYLMKNLRSRLMATQAWLEARL
                     KGEELPKPEGLLTQNEELWEPLYACYQSLQACGMGIIANGDLLDTLRRVKCFGVPLVR
                     IDIRQESTRHTEALGELTRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWQPSAE
                     TREVLDTCQVIAEAPQGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETL
                     DDLNNANDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIK
                     TCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLP
                     EITVSSLSLYTGAILEANLLPPPEPKESWRRIMDELSVISCDLYRGYVRENKDFVPYF
                     RSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQK
                     VVEDGKQSELEAMCRDWPFFSTRLGMLEMVFAKADLWLAEYYDQRLVDKALWPLGKEL
                     RNLQEEDIKVVLAIANDSHLMADLPWIAESIQLRNIYTDPLNVLQAELLHRSRQAEKE
                     GQEPDPRVEQALMVTIAGIAAGMRNTG"
     gene            16965..18698
                     /locus_tag="RHX21_001816"
     CDS             16965..18698
                     /locus_tag="RHX21_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709755.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase CptA"
                     /protein_id="HDV1987003.1"
                     /translation="MHSTEVQAKPLFSWKALGWALLYFWFFSTLLQAIIYISGYSGTN
                     GIRDSLLFSSLWLIPVFLFPKRIKIIAAVIGVVLWAASLAALCYYVIYGQEFSQSVLF
                     VMFETNTNEASEYLSQYFSLKIVLIALAYTAVAVLLWTRLRPVYIPKPWRYVVSFALL
                     YGLILHPIAMNTFIKNKPFEKTLDNLASRMEPAAPWQFLTGYYQYRQQLNSLTKLLNE
                     NNALPPLANFKDESGNEPRTLVLVIGESTQRGRMSLYGYPRETTPELDALHKTDPNLT
                     VFNNVVTSRPYTIEILQQALTFANEKNPDLYLTQPSLMNMMKQAGYKTFWITNQQTMT
                     ARNTMLTVFSRQTDKQYYMNQQRTQSAREYDTNVLKPFQDVLNDPAPKKLIIVHLLGT
                     HIKYKYRYPENQGKFDGNTDHVPPGLSAEELESYNDYDNANLYNDHVVASLIKDFKAA
                     DPNGFLVYFSDHGEEVYDTPPHKTQGRNEDNPTRHMYTIPFLLWTSEKWQATHPRDFS
                     QDVDRKYSLAELIHTWSDLAGLSYDGYDPTRSVVNPQFKETTRWIGNPYKKNALIDYD
                     TLPYGDQVGNQ"
     gene            18913..19764
                     /locus_tag="RHX21_001817"
     CDS             18913..19764
                     /locus_tag="RHX21_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDV1987004.1"
                     /translation="MYHDVSYLLSRLINGPLSLRQIYFASSNGPVPDLAYQVDFPRLE
                     IVLEGEFVDTGAGATLVPGDVLYVAAGGWNFPQWKTPATTFSVLFGKQQLGFSVVQWD
                     GKQYQNLAKQHVARRGPRIGSFLLQTLNEMQMQPQEQQTARLIVASLLSHCRDLLGSQ
                     IQTASRSQALFEAIRDYIDERYASALTRESVAQAFYISPNYLSHLFQKTGAIGFNEYL
                     NHTRLEHAKTLLKGYDLKVKEVAHACGFVDSNYFCRLFRKNTERSPSEYRRQYHSQLT
                     EKPTTPE"
     gene            complement(19751..20092)
                     /locus_tag="RHX21_001818"
     CDS             complement(19751..20092)
                     /locus_tag="RHX21_001818"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HDV1987005.1"
                     /translation="MAYLVAVTACVSGVAHTYMAAERLEKLCLLEKWGVSIETQGALG
                     TENRLADEDIRRADVALLITDIELAGAERFEHCRYVQCSIYAFLREPQRVMSAVRKVL
                     SAPQQTHLILE"
     gene            complement(20094..20972)
                     /locus_tag="RHX21_001819"
     CDS             complement(20094..20972)
                     /locus_tag="RHX21_001819"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418387.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[formate-C-acetyltransferase]-activating enzyme"
                     /protein_id="HDV1987006.1"
                     /translation="MTSSAGQRISCNVVETRRNDVARIFNIQRYSLNDGEGIRTVVFF
                     KGCPHLCPWCANPESISGKIQTVRREAKCLHCAKCLRDADECPSGAFERIGRDISLDA
                     LEREVMKDDIFFRTSGGGVTLSGGEVLMQAEFATRFLQRLQLCGVSCAIETAGDAPAS
                     KLLPLAKLCDEVLFDLKIMDATQARDVVKMNLPRVLENLRLLVSEGVNVIPRLPLIPG
                     FTLSRENMQQALDVLIPLNIRQIHLLPFHQYGEPKYRLLGKTWSMKEVPAPSSADVAT
                     MREMAERAGFQVTVGG"
     gene            complement(20938..23235)
                     /locus_tag="RHX21_001820"
     CDS             complement(20938..23235)
                     /locus_tag="RHX21_001820"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HDV1987007.1"
                     /translation="MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRA
                     KATAYILEHVEISIRDEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFA
                     ISEEDKRIYREELFPYWEKRSMKDFINGQMTDEVKAATSTQIFSINQTDKGQGHIIID
                     YPRLLNHGLGELVAQMQQHCQQQPENHFYQAALLLLEASQKHILRYAELAETMAANCT
                     DAQRREELLTIAEISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYM
                     LPFYQTSLTQGEDAAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLT
                     ENGRSAVNVLSFLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRLGTGIPQIF
                     NDEVVVPAFLNRGVSLEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHEN
                     EGNAALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR
                     DITDGGARYNFSGVQGIGIANLSDSLHALKGMVFDQQRLSFDELLSVLKANFATPEGE
                     KVRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVP
                     LGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVK
                     FTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA
                     GYSAFFVELSKEIQDDIIRRTAHQL"
     gene            complement(23286..23606)
                     /locus_tag="RHX21_001821"
     CDS             complement(23286..23606)
                     /locus_tag="RHX21_001821"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HDV1987008.1"
                     /translation="MTKIIAVTACPSGVAHTYMAAEALESAAKAKGWEVKVETQGSIG
                     LENELTAEDVASADMVILTKDIGIKFEERFAGKTIVRVNISDAVKRADAIMSKIEAHL
                     AQTA"
     gene            complement(23621..24700)
                     /locus_tag="RHX21_001822"
     CDS             complement(23621..24700)
                     /locus_tag="RHX21_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HDV1987009.1"
                     /translation="MNELVQILKNTRQHLMTGVSHMIPFVVSGGILLAVSVMLYGKGA
                     VPDAVADPNLKKLFDIGVAGLTLMVPFLAAYIGYSIAERSALAPCAIGAWVGNSFGAG
                     FFGALIAGIIGGIVVHYLKKIPVHKVLRSVMPIFIIPIVGTLITAGIMMWGLGEPVGA
                     LTNSLTQWLQGMQQGSIVMLAVIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTVVAI
                     AAVGICVPPLGMGLATLIGRKNFSAEERETGKAALVMGCVGVTEGAIPFAAADPLRVI
                     PSIMVGSVCGAITAALVGAQCYAGWGGLIVLPVVEGKLGYIAAVAVGAVVTAVCVNVL
                     KSLARKNGSSTDEKEDDLDLDFEIN"
     gene            25009..27510
                     /gene="ptsP"
                     /locus_tag="RHX21_001823"
     CDS             25009..27510
                     /gene="ptsP"
                     /locus_tag="RHX21_001823"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDV1987010.1"
                     /translation="MALIVEFICELPNGVHARPASHVETLCNTFSSQIEWHNLRTDRK
                     GNAKSALALIGTDTLVGDNCQLLISGADEQEAHQRLSQWLRDEFPHCDAPLAEVKSDE
                     LEPLPVSLTNLNPQIIRARTVCSGSAGGILTPISSLDLNALSNLPAAKGVDAEQSALE
                     NGLTLVLKNIEFRLLDSDGATSAILEAHRSLAGDTSLREHLLAGVSAGLSCAEAIVAS
                     ANHFCEEFARSSSSYLQERALDVRDVCFQLLQQIYGEQRFPAPGKLTQPAICMADELT
                     PSQFLELDKNHLKGLLLKSGGTTSHTVILARSFNIPTLVGVDIDALTPWQHQTIYIDG
                     NAGAIVVEPGEAVARYYQQEARVQDALREQQRVWLTQQARTADGIRIEIAANIAHSVE
                     AQAAFGNGAEGVGLFRTEMLYMDRTSAPGESELYNIFCQALESANGRSIIVRTMDIGG
                     DKPVDYLNIPAEANPFLGYRAVRIYEEYASLFTTQLRSILRASAHGSLKIMIPMISSM
                     EEILWVKEKLAEAKQQLRNEHIPFDEKIQLGIMLEVPSVMFIIDQCCEEIDFFSIGSN
                     DLTQYLLAVDRDNAKVTRHYNSLNPAFLRALDYAVQAVHRQGKWIGLCGELGAKGSVL
                     PLLVGLGLDELSMSAPSIPAAKARMAQLDSRECRQLLNQAMACRTSLEVEHLLAQFRM
                     TQQDAPLVTAECITLESDWRSKEEVLKGMTDNLLLAGRCRYPRKLEADLWAREAVFST
                     GLGFSFAIPHSKSEHIEQSTISVARLQAPVRWGDDEAQFIIMLTLNKHAAGDQHMRIF
                     SRLARRIMHEEFRNALVNAASADAIASLLQHELEL"
     gene            27522..28184
                     /gene="fsa"
                     /locus_tag="RHX21_001824"
     CDS             27522..28184
                     /gene="fsa"
                     /locus_tag="RHX21_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDV1987011.1"
                     /translation="MELYLDTANVAEVERLARIFPIAGVTTNPSIIAASKESIWEVLP
                     RLQKAIGDEGILFAQTMSRDAQGMVEEAKRLRDAIPGIVVKIPVTSEGLAAIKLLKKE
                     GITTLGTAVYSAAQGLLAALAGAKYVAPYVNRVDAQGGDGIRTVQELQTLLEMHAPES
                     MVLAASFKTPRQALDCLLAGCESITLPLDVAQQMLNTPAVESAIEKFEHDWNAAFGTT
                     HL"
     gene            28195..29298
                     /gene="gldA"
                     /locus_tag="RHX21_001825"
     CDS             28195..29298
                     /gene="gldA"
                     /locus_tag="RHX21_001825"
                     /EC_number="1.1.1.6"
                     /EC_number="1.1.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418380.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional L-1,2-propanediol
                     dehydrogenase/glycerol dehydrogenase"
                     /protein_id="HDV1987012.1"
                     /translation="MDRIIQSPGKYIQGADVINRLGEYLKPLAERWLVVGDKFVLGFA
                     QSTVEKSFKDAGLVVEIAPFGGECSQNEIDRLRGIAETAQCGAILGIGGGKTLDTAKA
                     LAHFMGVPVAIAPTIASTDAPCSALSVIYTDEGEFDRYLLLPNNPNMVIVDTKIVAGA
                     PARLLAAGIGDALATWFEARACSRSGATTMAGGKCTQAALALAELCYNTLLEEGEKAM
                     LAAEQHVVTPALERVIEANTYLSGVGFESGGLAAAHAVHNGLTAIPDAHHYYHGEKVA
                     FGTLTQLVLENAPVEEIETVAALSHAVGLPITLAQLDIKEDVPAKMRIVAEAACAEGE
                     TIHNMPGGATPDQVYAALLVADQYGQRFLQEWE"
     gene            29573..30190
                     /locus_tag="RHX21_001826"
                     /pseudo
     CDS             29573..30190
                     /locus_tag="RHX21_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418379.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1287 domain-containing protein"
     gene            complement(30217..31122)
                     /gene="yijE"
                     /locus_tag="RHX21_001827"
     CDS             complement(30217..31122)
                     /gene="yijE"
                     /locus_tag="RHX21_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418378.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine transporter YijE"
                     /protein_id="HDV1987013.1"
                     /translation="MSAAGKSNPLAISGLVVLTLIWSYSWIFMKQVTSYIGAFDFTAL
                     RCIFGALVLFIVLLLRGRGMRPTPFNYTLVIALLQTCGMVGLAQWALVSGGAGKVAIL
                     SYTMPFWVVIFAALFLGERLRRGQYFAILIAAFGLFLVLQPWQLDFSSMKSAMLAILS
                     GVSWGASAIVAKRLYARHPRVDLLSLTSWQMLYAALVMSVVALLVPQREIDWQPTVFW
                     ALAYSAILATALAWSLWLFVLKNLPASIASLSTLAVPVCGVLFSWWLLGENPGAVEGS
                     GIVLIVLALALVSRKKKEAVSVKRI"
     gene            complement(31216..33396)
                     /gene="katG"
                     /locus_tag="RHX21_001828"
     CDS             complement(31216..33396)
                     /gene="katG"
                     /locus_tag="RHX21_001828"
                     /EC_number="1.11.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase/peroxidase HPI"
                     /protein_id="HDV1987014.1"
                     /translation="MSTSDDIHNTTATGKCPFHQGGHDQSAGAGTTTRDWWPNQLRVD
                     LLNQHSNRSNPLGEDFDYRKEFSKLDYYGLKKDLKALLTESQPWWPADWGSYAGLFIR
                     MAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWA
                     DLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLG
                     ATEMGLIYVNPEGPDHSGEPLSAAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAG
                     PTSNVGPDPEAAPIEEQGLGWASTYGSGVGADAITSGLEVVWTQTPTQWSNYFFENLF
                     KYEWVQTRSPAGAIQFEAVDAPEIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRR
                     FLNDPQAFNEAFARAWFKLTHRDMGPKSRYIGPEVPKEDLIWQDPLPQPIYNPTEQDI
                     IDLKFAIADSGLSVSELVSVAWASASTFRGGDKRGGANGARLALMPQRDWDVNAAAVR
                     ALPVLEKIQKESGKASLADIIVLAGVVGVEKAASAAGLSIHVPFAPGRVDARQDQTDI
                     EMFELLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTALVGGMRVLGANFD
                     GSKNGVFTDRVGVLSNDFFVNLLDMRYEWKAADESKELFEGRDRETGEVKYTASRADL
                     VFGSNSVLRAVAEVYASSDAHEKFVKDFVAAWVKVMNLDRFDML"
     gene            complement(33725..34615)
                     /gene="metF"
                     /locus_tag="RHX21_001829"
     CDS             complement(33725..34615)
                     /gene="metF"
                     /locus_tag="RHX21_001829"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HDV1987015.1"
                     /translation="MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNS
                     IDRLSSLKPKFVSVTYGANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATHDELRTI
                     ARDYWNNGIRHIVALRGDLPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAK
                     SAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFK
                     QAKKFADMTNVRIPAWMAQMFDGLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYT
                     LNRAEMSYAICHTLGVRPGL"
     gene            complement(34964..37396)
                     /gene="metL"
                     /locus_tag="RHX21_001830"
     CDS             complement(34964..37396)
                     /gene="metL"
                     /locus_tag="RHX21_001830"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase II"
                     /protein_id="HDV1987016.1"
                     /translation="MSVIAQAGAKGRQLHKFGGSSLADVKCYLRVAGIMAEYSQPDDM
                     MVVSAAGSTTNQLINWLKLSQTDRLSAHQVQQTLRRYQCDLISGLLPAEEADSLISAF
                     VSDLERLTALLDSGINDAVYAEVVGHGEVWSARLMSAVLNQQGLPAAWLDAREFLRAE
                     RAAQPQVDEGLSYPLLQQLLVQHPGKRLVVTGFISRNNAGETVLLGRNGSDYSATQIG
                     ALAGVSRVTIWSDVAGVYSADPRKVKDACLLPLLRLDEASELARLAAPVLHARTLQPV
                     SGSEIDLQLRCSYTPDQGSTRIERVLASGTGARIVTSHDDVCLIEFQVPASQDFKLAH
                     KEIDQILKRAQVRPLAVGVHNDRQLLQFCYTSEVADSALKILDEAGLPGELRLRQGLA
                     LVAMVGAGVTRNPLHCHRFWQQLKGQPVEFTWQSDDGISLVAVLRTGPTESLIQGLHQ
                     SVFRAEKRIGLVLFGKGNIGSRWLELFAREQSTLSARTGFEFVLAGVVDSRRSLLSYD
                     GLDASRALAFFNDEAVEQDEESLFLWMRAHPYDDLVVLDVTASQQLADQYLDFASHGF
                     HVISANKLAGASDSNKYRQIHDAFEKTGRHWLYNSTVGAGLPINHTVRDLIDSGDTIL
                     SISGIFSGTLSWLFLQFDGSVPFTELVDQAWQQGLTEPDPRDDLSGKDVMRKLVILAR
                     EAGYNIEPDQVRVESLVPAHCEGGSIDHFFENGDELNEQMVQRLEAAREMGLVLRYVA
                     RFDANGKARVGVEAVREDHPLASLLPCDNVFAIESRWYRDNPLVIRGPGAGRDVTAGA
                     IQSDINRLAQLL"
     gene            complement(37399..38559)
                     /gene="metB"
                     /locus_tag="RHX21_001831"
     CDS             complement(37399..38559)
                     /gene="metB"
                     /locus_tag="RHX21_001831"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HDV1987017.1"
                     /translation="MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAH
                     DYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYG
                     GSYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKIC
                     HLAREVGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDV
                     VTELAWWANNIGVTGGAFDSYLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLY
                     HPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRFLGGLSLFTLAESLGGVESLI
                     SHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGFRAANKG"
     gene            38836..39153
                     /gene="metJ"
                     /locus_tag="RHX21_001832"
     CDS             38836..39153
                     /gene="metJ"
                     /locus_tag="RHX21_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015855437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="met regulon transcriptional regulator MetJ"
                     /protein_id="HDV1987018.1"
                     /translation="MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRR
                     QVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGINPET
                     WEY"
     gene            39337..39945
                     /locus_tag="RHX21_001833"
     CDS             39337..39945
                     /locus_tag="RHX21_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX family permuted papain-like enzyme"
                     /protein_id="HDV1987019.1"
                     /translation="MKNRLLILSLLVSVPAFAWQPQTGDIIFQISRSSQSKAIQLATH
                     SDYSHTGMLVIRNKKPYVFEAVGPVKYTPLKQWIAHGEKGKYVVRRVEGGLSVEQQQK
                     LAQTAKRYLGKPYDFSFSWSDDRQYCSEVVWKVYQNALGMRVGEQQKLKEFDLSNPLV
                     QAKLKERYGKNIPLEETVVSPQAVFDAPQLTTVAKEWPLFSW"
     gene            40090..40765
                     /locus_tag="RHX21_001834"
                     /pseudo
     CDS             40090..40765
                     /locus_tag="RHX21_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477181.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
BASE COUNT         9998 a        11273 c        10296 g         9330 t
ORIGIN      
        1 tttgcttttc tctgttgaga ttctcaggag aaccccgctg acccggcggc gtgtttgccg
       61 ttgttccgtg tcagtggtgg cgcattatag ggagttattc cggcctgaca agaggaaatt
      121 taaaataatt ttctgaccgc gcaacattca accaaatcag cctaaaactg ccagtttttc
      181 gagcgtttcg aagccgtaac gctgtaaaac gggcaataat tgttcagctt ctggcgtcat
      241 tgccatacaa aaggcaatat tcgcatcggc agattttgca tccggggctt catgttctaa
      301 caaccaggcc gttcggcgag caatcgctgc gccagaatcc accagccggg ttccctctgg
      361 cagcacttgt aacagttctt cttgtagtag agggaaatgg gtgcaaccca atacaacggt
      421 atctggcggc tctttcattc ttaaccacgg gcgtaggata cgttttagtg catccagaga
      481 aacatcttcg ccatgtagct tcgcttcagc caactcaacc atctctgccg agcccagcat
      541 ttctatctgg cattcattag cgaaacgcgc gatcagctca tgagtataag aacgtttaac
      601 tgttccgcgg gttgccagta atccgacaat gccatttgcc gtcagacgtg cagcaggttt
      661 aatcgccggc acgacaccaa caaccgggaa gtcgaacttt tcgcgtaatg caggaagtga
      721 aacggtactg gcagtgttgc aagcgaccac agccagcgca aggggataac gttcttgcac
      781 cgcggtgaca attgccacca ctcgctcaac aataaacgct tcgctttttt cgccatacgg
      841 gaaagcgacg ttatcgaaag cataaatgta atggagatcc ggtaagagat gccggatctc
      901 gtcatagacc gacaacccac cgacgccgga gtcaaacacc agcacggtgg gacgtggttc
      961 agaaggtgta gctgccagac aaggtgtatt cccgtcctgc agtttggtag ccatagactg
     1021 tctcataatc tttgtcgaac aggttggcta ttttaccacg aactgtcagg tgagaggtga
     1081 ccggatacgc aaccgcaaga tcccacaagc tcacaccgcc cattttaacg gtttgataag
     1141 gataagatga gtaatcctta tcatagcgag tgcctaaata ctgataagta ataccccagt
     1201 cgaagtcata caactgccag tcgagctggt atttcacctg ctgtttagca cggcgtaaca
     1261 acggcgtgtc ggtaatcgca ttgcgcgcat cgacataatc ataactcaca gtatgcgtca
     1321 gtggtccggt atcaaaattg gcggtcgcct cgacgccctt aatccgcgct ttcccttcgt
     1381 tgtaatattt cagggtgtga tcatcataat cgatcaagtc actgacatcg ttacgatatc
     1441 cggaaatacg ccagttcacc ccagcggtta agccttcaaa cgcgccttcc cactgtttgc
     1501 ttttctccgg gtccagattc ggatttccgt agaagccata cagttgcccc agatttggtg
     1561 ccttataaga tgtcccgtag gaagcaatga agcgataacc ttcgatgaat tcccaaccgg
     1621 cgctggtttg ccaggttcca tgacgaccaa actgtgagtt atcgtcgctg cgtgctgcgc
     1681 cttcaaaggt aaaatcgccg acttgttgca gcccggtcag atagatgcca gtattacgtt
     1741 gatcatatcc atcctcaaca taacctgtac ccggcgtcgt agtctgtttc tgccagtcga
     1801 cacccgcacc aatactaccg tgaccaacga tgacattgtt tgcccactgg acggtgtatt
     1861 gcttcatctc atcgagcgtc gccgacgaat cataacgacc ataatgggga tcgtagttgt
     1921 aatctttgct atggctatag ctggtaatga gttgtgattt aatcagttcg ccgttatagc
     1981 gcagcccggc gtcccaactt tgactataga gtttacgggt atcgaccaat ggtgaacccg
     2041 gagaataata cgcgtcataa ttggtacggt tatcatagcc atagccgcgc acaaagccgc
     2101 tccaggcatc agtaaagtta tgctccagcg cgccataaag cgttttactt aaaaaaccat
     2161 ctttatctgg ctgcgcttgc gttccggtat taccataggc aacaacatca taaccatgag
     2221 tataggcata atcgcccaac aacgttactc gtgtcttatc ccccagttgt tgctgtgtag
     2281 agacatcata gttttgataa ctattgcttc cccaccctgc tgaaatttcc gttccgggtt
     2341 catcgcgcgt cgtgatgata ttcaccaccc cacctattgc atcggaacca taaacggcgg
     2401 agcgtggccc acggatatat tcaacacgct ggacaagcgc aatagggaac tggctaaggt
     2461 cggcagaacc actcaccccc gccagattca ggcgtacgcc atcaattaac accaacacat
     2521 gactggcatt tgtaccgcga ataaaaatag atgagagctg acctgaaccg ccgttttggg
     2581 tgatatcgac gcccggaaga cggcgcagca catcattaac cgaggtcgac tgccagcggt
     2641 cgatatcctg acgcgtcaca acggtggttg gtgcaagcac agtgctgcgc ggctgttcaa
     2701 aacggttagc agtaacgacg agagtatccg ggctggtatc ctgtgcccaa gcggaaaagg
     2761 ctgtgacaga acacgccgtc agcagcgaag cttttttaat cattgtaaag catccacaat
     2821 agaagaagga tgccgcaggt ttcatcaata ttacgcgatg atgagaacca gatgcgacgt
     2881 tggccggcag gtcttcgggc ttggaggggt atctaagata ctaagagatg atgacttccc
     2941 accgaatggc agtgtccgca taacgcaatc atcgcacctt tccttaccgc tgcgcgtcag
     3001 ctccagattc gcactggatt ccctattaac tcacaggacc ggcaagtgga tgctacaggt
     3061 tgtaacaagt tactgtccag acgtagctca caaataggaa ttcatcaaga tctggacatc
     3121 tgatgagcaa tccctacaat cgccgcgtac tttaattttt caggatacat catgaccccc
     3181 gaacaccttc caacagaaca gtatgaagcg cagttagccg aaaaagtggt acgtttgcaa
     3241 agtatgatgg caccgttttc tgacctggtt ccggaagtgt ttcgctcgcc ggtcagtcat
     3301 taccggatgc gcgcggagtt ccgcatctgg cacgatggcg atgacctgta tcacatcatt
     3361 ttcgatcaac aaaccaaaag ccgcatccgc gtggatagct tccccgccgc cagtgaactt
     3421 atcaaccagt tgatgacggc gatgattgcg ggtgtgcgta ataatcccgt tctgcgccac
     3481 aagttgttcc agattgatta cctcactacg ctgagtaatc aggcggtggt ttccctgcta
     3541 taccataaga agctggatga tgagtggcgt caggaagcgg aggccctgcg cgatgcactg
     3601 cgcgcgcaga atctgaatgt gcatctgatt ggtcgggcaa cgaaaaccaa aatcgagctg
     3661 gatcaggatt acatcgatga acgtctgccg gtcgcaggga aagagatgat ctaccgtcag
     3721 gtagaaaaca gctttaccca gccgaacgcg gcgatgaata ttcagatgct ggaatgggcg
     3781 ctggacgtaa ccaaaggctc aaaaggcgat ttactggagc tgtactgcgg caacggtaac
     3841 ttttcattag cgctggcgcg caattttgat cgggtattag ccaccgaaat cgctaagccg
     3901 tcggttgctg ctgcgcaata caacatcgca gctaaccata ttgataacgt acaaattatt
     3961 cgtatggcgg cagaagaatt tactcaggcg atgaatggtg tgcgcgagtt taaccgcctg
     4021 caagggatcg acttaaagag ttatcagtgc gaaaccattt ttgtcgaccc accgcgcagc
     4081 ggtctggaca gtgaaaccga gaaaatggtg caggcgtatc cgcgtatttt gtacatctcc
     4141 tgtaacccgg aaacgttatg taagaatctg gaaacattaa gccagacgca caaggtcgaa
     4201 cgtctggctc tgtttgatca gttcccctac acgcaccata tggagtgcgg cgtattactg
     4261 accgcgaagt aaaacccatg ccggatgcgc cagcatccgg cataataccg attactcagc
     4321 aacttcctgc ttacggttac gcatcttcgc gccaatccag aacaccataa tgacggagag
     4381 tactgccggg aagaagttag agccgatatc cggatattcc gcacgaacta ccgtgctgta
     4441 cagcagtacg ccgagaataa aacaggcagc tgccagaccc ggcaagccta ccggcaagcc
     4501 taccggcata gtgcgattaa gataacgttg atgcaggcag taaaccgtca gcaccaggga
     4561 aataatcggg aatacagaaa atggcacaat ggagctaaac agcgggtgat gctgccaact
     4621 tactgattta gtgtatgatg gtgtttttga ggtgctccag tggcttctgt ttctatcagc
     4681 tgtccctcct gttcagctac tgacggggtg gtgcgtaacg gcaaaagcac cgccggacat
     4741 cagcgctatc tctgctctca ctgccgtaaa acatggcaac tgcagttcac ttacaccgct
     4801 tctcaacccg gtacgcacca gaaaatcatt gatatggcca tgaatggcgt tggatgccgg
     4861 gcaacagccc gcattatggg cgttggcctc aacacgattt tacgtcactt aaaaaactca
     4921 ggccgcagtc ggtaacctcg cgcatacagc cgggcagtga cgtcatcgtc tgcgcggaaa
     4981 tggacgaaca gtggggctat gtcggggcta aatcgcgcca gcgctggctg ttttacgcgt
     5041 atgacaggct ccggaagacg gttgttgcgc acgtattcgg tgaacgcact atggcgacgc
     5101 tggggcgtct tatgagcctg ctgtcaccct ttgacgtggt gatatggatg acggatggct
     5161 ggccgctgta tgaatcccgc ctgaagggaa agctgcacgt aatcagcaag cgatatacgc
     5221 agcgaattga gcggcataac ctgaatctga ggcagcacct ggcacggctg ggacggaagt
     5281 cgctgtcgtt ctcaaaatcg gtggagctgc atgacaaagt catcgggcat tatctgaaca
     5341 taaaacacta tcaataagtt ggagtcatta ccaaacagcg ctgcgaaagt accattaatc
     5401 gataagccag caactaacgc cagcagcagc gtacctctat cttgatttgc ttgtttcatt
     5461 actcgtcctt cacatttccc ggaataattg cggttttctc ttgttcacgg cgataccagt
     5521 aataagcccc tttcgaaatc attcgcagtt gcagtaccag tcgctcttct aattgccgac
     5581 gttgttcgac gccgacgtcc aacgcctcgg cacccgcact gaagacaatt gtcaccattg
     5641 cttcggcttg cgcttcagta aacgcacgcg gcatatggtt ttcgagttcc agatagtccg
     5701 caagttccgc aatgaagtgc tgaatttcac gcgcaacggc ggcacgaaac gcagcggagg
     5761 tgccggagcg ttcccgcaat aataaccgga aggcgttagg attattaccg atgaactcca
     5821 taaatgtgga gaccgaggtg cggatcacac tcccgccttt ggcgatacgc tgacgcgcct
     5881 ggcgcatgag ttggcgtagc attaaaccgc tctcatcaac catggtcaga cccagttcgt
     5941 ctacgtcgcg gaaatgccga taaaaagagg tgggagcaat gcccgcttca cgcgccactt
     6001 cacgcaaact caggctggcg aagctgcgtt cagcacttaa ttggctaaat gcggcttcca
     6061 ccagcgaacg gcgggttttt tctttttgtt gcgctcttac gcccatcacg atgtctgaat
     6121 ccttgccaaa agtactgctg gcactatacc agagaatgaa catactggat tgctccagta
     6181 ttgtgaatga acggtaacgc aataaaacat atttactgca attctttggc cggttctttt
     6241 acgtacagcg gaaacctgcc gcttaaacgg agagtatcgt cgataaaaat ccaataaaac
     6301 gtcagggcaa aagtaagaaa cagacaaagc aaaggccgct caggatatag ccagataaat
     6361 gacggggatc aattggctta cccgcgataa aatgttatca ttctgttgct tttatgtata
     6421 agaacaggta agccctacca tgccacattc ctacgattac gatgccatag taataggttc
     6481 cggccccggc ggcgaaggcg ctgcaatggg cctggttaag caaggtgcgc gcgtcgcagt
     6541 tatcgagcgt tatcaaaatg ttggcggcgg ttgcacccac tggggcacca tcccgtcgaa
     6601 agctctccgt cacgccgtca gccgcattat agaattcaat caaaacccac tatacagcga
     6661 ccattcccgg ctgctccgct cttcttttgc cgatatcctt aaccatgccg ataacgtgat
     6721 taatcaacaa acgcgcatgc gtcagggatt ttacgaacgt aatcactgtg aaatattgca
     6781 ggggaacgct cgctttgttg acgagcatac gttggcgctg gattgcccgg acggcagcgt
     6841 tgaaacacta accgctgaaa aatttattat tgcctgcggc tctcgtccat atcatccaac
     6901 agatgttgat ttcacccatc cacgcattta cgacagcgac tcaattctta gcatgcacca
     6961 cgaaccgcgc catgtactta tctatggtgc tggagtgatc ggctgtgaat atgcgtcgat
     7021 cttccgcggt atggatgtaa aagtggatct gatcaacacc cgcgatcggc tgctggcatt
     7081 tctcgatcaa gagatgtcag attctctctc ctatcacttc tggaacagtg gcgtagtgat
     7141 tcgccacaac gaagagtacg agaagatcga aggctgtgac gacggtgtga tcatgcatct
     7201 gaagtcgggt aaaaaactga aagctgactg cctgctctat gccaacggtc gcaccggtaa
     7261 tactgattcg ctggcgttac agaacattgg gctggaaact gacagtcgcg gacagctgaa
     7321 ggtcaacagc atgtatcaga ccgcacagcc gcacgtttac gcggtgggcg acgtgattgg
     7381 ttatccgagc ctggcgtcgg cggcctatga ccaggggcgc attgccgcgc aggcgctggt
     7441 gaaaggtgaa gccaccgcac atctgattga agatatccct accggcattt acaccatccc
     7501 ggaaatcagc tctgtgggca aaaccgaaca gcagctgacc gcgatgaaag tgccatatga
     7561 agtgggccgc gcccagttca aacatctggc acgtgcacaa atcgtcggca tgaacgtggg
     7621 cacgctgaaa attttgttcc atcgggaaac aaaagagatt ctgggcattc actgctttgg
     7681 cgagcgcgct gccgaaatta ttcatatcgg tcaggcgatt atggaacaga aaggtggcgg
     7741 caacactatt gagtacttcg tcaacaccac ctttaactac ccgacgatgg cggaagccta
     7801 tcgggtagct gcgctaaatg gcttaaaccg cctgttttaa cactttatcg aaatggccat
     7861 ccattcttgc gcggatggcc tctgccagct gctcatagcg gctgcgcagc ggtgagccag
     7921 gacgataaac caggccaatc gtgcggcgag gttccggctt aatacacggc aaataaacaa
     7981 ccccatcgcg tttgcgctcc ggcggcacag ccagcgcagg cagtaaagtg atcccgctac
     8041 ctgccgccac catgttacgc agtgtctcca ggctggtcgc gcggaagtgt gtatcttcat
     8101 ccgccccggc ttcaaagcag aaacccattg cctgatcgcg caaacagtga ccatcttcca
     8161 gcatcagcag tttttcccct gccagatcgg ccatcggtac gcattcgcgg ttcgcccacg
     8221 ggtgatcttc atagatagcc agcaacattg gctcatcaaa caacggcact tcaatgaatg
     8281 cttcgctctc tttcaccagc gcgaggatca cgcaatcgag tttgccactg tccagttgcg
     8341 ccagtaactg gtgggtctgt gcttcatgca gatacatttc cagctttgga aaggtctggt
     8401 gcagcatcgg gataatatgc ggtagcaggt acggtccaac cgtgggaatc aaaccaatat
     8461 gcagcggtcc ggacatcgtc tcgccctgct ggcttgccat ctctttaagg actttcacct
     8521 cacgcagcac ggtacgcgcc tgatccacca gcagcattcc cgcctgggtg aacaacactt
     8581 tacggctggt ccgctccagc aacatcacgc ccaactcatc ttccagctta cgaatttgcc
     8641 cgctaagcgt cggctggcta acgtggcagg aatctgccgc acgccgaaaa tggcggtgtt
     8701 cagccaatgc caccaggtac tcaagatcac gaatattcat tatccatcct ccatcgccac
     8761 gatagttcat ggcgataggt agaatagcaa tgaacgatta tccctatcaa gcattctgac
     8821 tgataattgc tcacagaaac ggagcggcac ctcttttaac ccttgaagtc actgcccgtt
     8881 tcgagagttt ctcaactcga ataactaaag ccaacgtgaa cttttgcgga tctccaggat
     8941 ccgctttttt ttgccataaa aaagcccggc gataagccag gctcaaattt gtacatataa
     9001 atgttcttac cccaaccgag cctgcgcaaa agcaatcgcc tgcgccacct gctgcggtga
     9061 gacgccgcct tttgccgcac gcttgtcgag gcacgattgc agcgacagaa tcggatagac
     9121 atcttcgtca atcacctgac tgaatttctg caactcactg agcggcagat cttccagcgg
     9181 tttgccctga cgaatggctt ccaccaccgc ttcaccaaca atatggtgcg cctcgcggaa
     9241 cggtacgcct ttcgccacca gataatccgc cagttcggtg gcgttggcgt aaccctgctg
     9301 agccgcttcc tggcaacgtg gacgtttcac ctgaatgccg tccagcacca gcgccgccat
     9361 atgcaggcag tccagccagg tatcgagcgc gtcgaacaga ccttctttgt cttcctgcat
     9421 atctttgttg taagccagcg gcaaaccttt cagcgtcatc atcatgccgg ttaacgcccc
     9481 ctgcacccga ccgcatttac cgcgaatcag ctccagcgca tccgggtttt tcttctgcgg
     9541 cattaatgat gaaccggaag tcacgcggtc agaaagctcc acaaaccccg cttcgccggt
     9601 gttaaagaaa atcagatctt cagcaaaacg cgacagatgc accatgccga tagcggcagc
     9661 agaaagcagt tccaacacat ggtcacggtc agaaacgctg tcgagactgt tacgggtcgc
     9721 cgaagcaaag cccagccagc ctgctaactg ttcacggtcg atttcatagg ccgttcccgc
     9781 cagcgcgcca cagcctagcg ggctgacatc cagacgctta agcgcatcct gcaaacggct
     9841 ttcatcacgc gccagcatct caacataggc caggcaccag tgcgcgaacg tcaccggctg
     9901 ggcgcgttgc aggtgagtgt aacctggcat taccgcgtcc tgattgtttt gtgcggtttc
     9961 caccagcgcc gattgcagct gccggttagc cgtcagtaac tcgctaacgg tatctttgca
    10021 ccacagtttc aggtcagtcg ctacctgatc attacggcta cgcccggtat gcagcttttt
    10081 gcctaactgg cccactttgt cgatcagttt gccttccacc cagctatgga tatcttcggc
    10141 gtcgctttca aggatttgtt gtggcctggc gcgaacatct tccagcaaca cgttcagcgc
    10201 ctcttccagt tgcgcctgct cttctgcggt taacacgcct accgtgacca gggctttgga
    10261 ccaggccaca gagccaacaa tatcctgctc cgccagacgg taatcaaagc gcagtgagtc
    10321 gttgaattgt ttgaaccgtt gatctgctgc ctgggtaaaa cgcccgcccc aaagtgccat
    10381 aactctgttt ccttattttg aaattcaatg ccggaaagct gcgcctccgg ccaacaaaac
    10441 ttaagctaaa atccgcgtac ccatcggcat accgttaaac agtgccggaa gctgctccgc
    10501 atgacgccag gaggcgatat ctaccggacg gcccagcgtg cgggccgcat ccagcgccgc
    10561 gttcactttc actatcatgc cgtcagtaat aatgccctgc tcaatcagtt gttctgcttt
    10621 cgcggcggtc atttcggcaa tgcgttgccc tttgccgtcg agaatgccgc tgacgtcgga
    10681 gagcaaaatc agatccgcgc ccagcgttgc cgccagcgcc gttgccgcct ggtcggcatt
    10741 gacgttcatc agttgccctt cgtctgttac gccaatggag ctgaccaccg gcagataacc
    10801 gttctccagc aaggagttga taagcttagg cgaacctggc tgcgccagtc caacatgacc
    10861 taactcttca tcaagctggg tcactttgac gctgtcgccg tcaccgagaa acaaacctac
    10921 ggccgcaatc tgatgtttct tcgcccatgc caacagggtt ttatttgccg ttcccgccag
    10981 tgctccggtg ataatgtcta tctgatcagc aggcgtcacc cgcaggccgt ttttcttttt
    11041 caccggcaga ttcagccctt tcatcagctc atccaccacg caaccgccgc cgtgcacaat
    11101 caccagcgga cgctgatgtg actcacgata attcaccagt gcgctaaaca gacgttccag
    11161 cgcctcttca ctatccagca gtacgccgcc cagtttgata attaatggat tcatcattgc
    11221 acccttaaat aagagactgc gtttccgcat agccgaaacg aatattggcg cactgtaccg
    11281 cttgtgccgc cgcgcctttc agtaagttgt cttcggtcgc cacaataatc aaatgctcgc
    11341 cctgaacggc aaacccgata tcgcaaaatg gcagcccaac gacatttttc agcgccggaa
    11401 cgcctttgtc atacagccgc accagcggtt tatgggcata cgcctgctgt aacacttgcg
    11461 cgacttgcgc ctgggtcaca cccgatttca ggcggcaggt aatggtttcg agaatgccgc
    11521 gcgggaaatt gcccagatgt ggggtgaaga taacgtcagc accgaggtgt gtggcgatct
    11581 ctggttgatg gcgatgagta aagacgccat acggttgcag gctaacttca caaaagctgt
    11641 ttgaaatggc cgctttacgc cctgcaccgc tcacgccgct ggtggcgttg atcaccggcc
    11701 actgattgag gtcaagaaga tcggcatcaa tcaacggttt cagcgccagc tgtgccgccg
    11761 tcggataaca gcccggcacc gcaatcaaat tcgcttcttt taatttatta ccgcaccact
    11821 ccgccagacc gtaggctgcc tgttccaaca gttccgggta ttgatgggta aagccgtaat
    11881 atttttcata gaaggtggcg tcgttaacac gaaacgcgcc ggaaaggtcg aacaccacgc
    11941 agcccgcttc aagaaactgc ggcgctaaat cgtggctaac ttcatgggcg gtggcgagaa
    12001 acactacgtc cacccctggg ctaaactcgc tgatatccga catcggctgc aacggcagat
    12061 caacgatgcc ttttagctgc ggatgcaaat cggagattaa ctttcccgca tcattgcttt
    12121 gcgctgaaac agtcaaagcg gttatgttca tatgcggatg gcgatttaca taggtcacta
    12181 gctctgcgcc agcgtagccg ctggcaccca caatcagcgt attcaacatc ggggctattc
    12241 accttcttat gtctggttgc caggttaaac gtaaaacatt caccttacgg ctggtgggtt
    12301 ttattacgct caacgttagt gtatttttat tcataaatac tgcatgaata ttgatactat
    12361 catgaccaga ggtgtgtcaa caatgaaaaa caaattaccg ccatttatcg agatttaccg
    12421 cgctctgatt gccacacctt caataagcgc cacggaagag gcactcgatc aaagcaatgc
    12481 agatttaatc actctgctgg cggactggtt taaagatttg ggcttcaatg tggaagtgca
    12541 gcctgttcca ggaactcgca acaaattcaa tatgctggca agtatcggac agggggctgg
    12601 cggcttgttg ctggcggggc ataccgatac ggtgccattt gatgacggtc gctggacgcg
    12661 cgatccgttt acactgacgg agcatgacgg caagctttac ggcttaggca ccgccgacat
    12721 gaaaggcttt tttgcgttta tccttgatgc gctacgcgat gtcgacgtca cgaaactgaa
    12781 aaaaccgctc tacattctgg cgactgctga tgaagaaacc agtatggccg gagcgcgtta
    12841 ttttgccgaa actaccgccc tgcgcccgga ttgcgccatc attggcgaac cgacgtcact
    12901 acaaccggta cgcgcacata aaggtcatat ctctaacgcc atccgtattc agggccagtc
    12961 ggggcactcc agcgatccag cacgcggagt taacgctatc gaactaatgc acgacgccat
    13021 cgggcatatt ttgcaattgc gcgataacct gaaagaacgt tatcactacg aagcgtttac
    13081 cgtgccatac cctacgctca acctcgggca tattcacggt ggcgacgctt ctaaccgtat
    13141 ttgcgcttgc tgtgagttgc atatggatat tcgtccgctg cctggcatga cactcaatga
    13201 acttaatggt ttgctcaacg atgcattggc tccggtgagc gaacgctggc cgggtcgtct
    13261 gacggtcgac gagctgcatc cgccgatccc tggctatgaa tgcccaccga atcatcaact
    13321 ggttgaagtg gttgagaaat tgctcggagc aaaaaccgaa gtggtgaact actgtaccga
    13381 agcgccgttt attcaaacgt tatgcccgac gctggtgttg gggcctggct caattaatca
    13441 ggctcatcaa cctgatgaat atctggaaac acggtttatc aagcccaccc gcgaactgat
    13501 aacccaggta attcaccatt tttgctggca ttaaaacgta ggccggataa ggcgctcgcg
    13561 ccgcatccgg cgctgttgcc aaactccagt gccgcaataa tgtcggatgc gatgcttgcg
    13621 catcttatcc gacctacagt gactcaaacg atgcccaacc gtaggccgga taaggcgctc
    13681 gcgccgcatc cggcactgtt gccaaactcc agtgccgcaa taatgtcgga tgcgatactt
    13741 gcgcatctta tccgaccgac agtgactcaa acgatgccca actgtaggcc ggataaggcg
    13801 ctcgcgccgc atccggcact gttgccaaac tccagtgccg caataatgtc ggatgcgata
    13861 cttgcgcatc ttatccgacc tacacctttg gtgttacttg gggcgatttt ttaacatttc
    13921 cataagttac gcttatttaa agcgtcgtga atttaatgac gtaaattcct gctatttatt
    13981 cgtttgctga agcgatttcg cagcatttga cgtcaccgct tttacgtggc tttataaaag
    14041 acgacgaaaa gcaaagcccg agcatattcg cgccaatgcg acgtgaagga tacagggcta
    14101 tcaaacgata agatggggtg tctggggtaa tatgaacgaa caatattccg cattgcgtag
    14161 taatgtcagt atgctcggca aagtgctggg agaaaccatc aaggatgcgt tgggagaaca
    14221 cattcttgaa cgcgtagaaa ctatccgtaa gttgtcgaaa tcttcacgcg ctggcaatga
    14281 tgctaaccgc caggagttgc tcaccacctt acaaaatttg tcgaacgacg agctgctgcc
    14341 cgttgcgcgt gcgtttagtc agttcctgaa cctggccaac accgccgagc aataccacag
    14401 catttcgccg aaaggcgaag ctgccagcaa cccggaagtg atcgcccgca ccctgcgtaa
    14461 actgaaaaac cagccggaac tgagcgaaga caccatcaaa aaagcagtgg aatcgctgtc
    14521 gctggaactg gtcctcacgg ctcacccaac cgaaattacc cgtcgtacac tgatccacaa
    14581 aatggtggaa gtgaacgcct gtttaaaaca gctcgataac aaagatatcg ctgactacga
    14641 acacaaccag ctgatgcgtc gcctgcgcca gttgatcgcc cagtcatggc ataccgatga
    14701 aatccgtaag ctgcgtccaa gcccggtaga tgaagccaaa tggggctttg ccgtagtgga
    14761 aaacagcctg tggcaaggcg taccaaatta cctgcgcgaa ctgaacgaac aactggaaga
    14821 gaacctcggc tacaaactgc ccgtcgaatt tgttccggtc cgttttactt cgtggatggg
    14881 cggcgaccgc gacggcaacc cgaacgtcac tgccgatatc acccgccacg tcctgctact
    14941 cagccgctgg aaagccaccg atttgttcct gaaagatatt caggtgctgg tttctgaact
    15001 gtcgatggtt gaagcgaccc ctgaactgct ggcgctggtt ggcgaagaag gtgccgcaga
    15061 accgtatcgc tatctgatga aaaacctgcg ttctcgcctg atggcgacac aggcatggct
    15121 ggaagcgcgc ctgaaaggcg aagaactgcc aaaaccagaa ggcctgctga cacaaaacga
    15181 agaactgtgg gaaccgctct acgcttgcta ccagtcactt caggcgtgtg gcatgggtat
    15241 tatcgccaac ggcgatctgc tcgacaccct gcgccgcgtg aaatgtttcg gcgtaccgct
    15301 ggtccgtatt gatatccgtc aggagagcac gcgtcatacc gaagcgctgg gcgagctgac
    15361 ccgctacctc ggtatcggcg actacgaaag ctggtcagag gccgacaaac aggcgttcct
    15421 gatccgcgaa ctgaactcca aacgtccgct tctgccgcgc aactggcaac caagcgccga
    15481 aacgcgcgaa gtgctcgata cctgccaggt gattgccgaa gcaccgcaag gctccattgc
    15541 cgcctacgtg atctcgatgg cgaaaacgcc gtccgacgta ctggctgtcc acctgctgct
    15601 gaaagaagcg ggtatcgggt ttgcgatgcc ggttgctccg ctgtttgaaa ccctcgatga
    15661 tctgaacaac gccaacgatg tcatgaccca gctgctcaat attgactggt atcgtggcct
    15721 gattcagggc aaacagatgg tgatgattgg ctattccgac tcagcaaaag atgcgggagt
    15781 gatggcagct tcctgggcgc aatatcaggc acaggatgca ttaatcaaaa cctgcgaaaa
    15841 agcgggtatt gagctgacgt tgttccacgg tcgcggcggt tccattggtc gcggcggcgc
    15901 acctgctcat gcggcgctgc tgtcacaacc gccaggaagc ctgaaaggtg gcctgcgcgt
    15961 gactgaacag ggcgagatga tccgctttaa atatggtctg ccagaaatca ccgtcagcag
    16021 cctgtcgctg tacaccgggg cgattctgga agccaacctg ctgccaccac ctgagccgaa
    16081 agagagctgg cgtcgcatta tggatgaact gtcagtcatc tcctgcgatc tctaccgtgg
    16141 ctacgtacgt gaaaacaaag attttgtgcc ttacttccgc tccgctacgc cggaacaaga
    16201 attgggcaaa ctgccgttgg gttcacgtcc ggcgaaacgt cgcccaaccg gcggcgtcga
    16261 gtcactacgc gccattccgt ggatcttcgc ctggacgcaa aaccgtctga tgctccccgc
    16321 ctggctgggt gcaggtacgg cgctgcaaaa agtggtcgaa gacggcaaac agagcgagct
    16381 ggaggctatg tgccgcgatt ggccattctt ctcgacgcgt ctcggcatgc tggagatggt
    16441 cttcgccaaa gcagacctgt ggctggcgga atactatgac caacgcctgg tagacaaagc
    16501 actgtggccg ttaggtaaag agttacgcaa cctgcaagaa gaagacatca aagtggtgct
    16561 ggcgattgcc aacgattccc atctgatggc cgatctgccg tggattgcag agtctattca
    16621 gctacggaat atttacaccg acccgctgaa cgtattgcag gccgagttgc tgcaccgctc
    16681 ccgccaggca gaaaaagaag gccaggaacc ggatcctcgc gtcgaacaag cgttaatggt
    16741 cactattgcc gggattgcgg caggtatgcg taataccggc taatcttcct cttctgcaaa
    16801 ccctcgtgct tttgcgcgag ggttttctga aatacttctg ttctaacacc ctcgttttca
    16861 atatatttct gtctgcattt tattcaaatt ctgaatatac cttcagatat ccttaaggaa
    16921 ttgtcgttac attcggcgat attttttcaa gacaggttct tactatgcat tccacagaag
    16981 tccaggctaa acctcttttt agctggaaag ccctgggttg ggcactgctc tacttttggt
    17041 ttttctctac tctgctacag gccattattt acatcagtgg ttatagtggc actaacggca
    17101 ttcgcgactc gctgttattc agttcgctgt ggttgatccc ggtattcctc tttccgaagc
    17161 ggattaaaat tattgccgca gtaatcggcg tggtgctatg ggcggcttct ctggcggcgc
    17221 tgtgctacta cgtcatctac ggtcaggagt tctcgcagag cgttctgttt gtgatgttcg
    17281 aaaccaacac caacgaagcc agcgagtatt taagccagta tttcagcctg aaaattgtgc
    17341 ttatcgcgct ggcctatacg gcggtggcag ttctgctgtg gacacgcctg cgcccggtct
    17401 atattccaaa gccgtggcgt tatgttgtct cttttgccct gctttatggc ttgattctgc
    17461 atccgatcgc catgaatacg tttatcaaaa acaagccgtt tgagaaaacg ttggataacc
    17521 tggcctcgcg tatggagcct gccgcaccgt ggcaattcct gaccggctat tatcagtatc
    17581 gtcagcaact aaactcgcta acaaagttac tgaatgaaaa taatgccttg ccgccactgg
    17641 ctaatttcaa agatgaatcg ggtaacgaac cgcgcacttt agtgctggtg attggcgagt
    17701 cgacccagcg cggacgcatg agtctgtacg gttatccgcg tgaaaccacg ccggagctgg
    17761 atgcgctgca taaaaccgat ccgaatctga ccgtgtttaa taacgtagtt acgtctcgtc
    17821 cgtacaccat tgaaatcctg caacaggcgc tgacctttgc caatgaaaag aacccggatc
    17881 tgtatctgac gcagccgtcg ctgatgaaca tgatgaaaca ggcgggttat aaaaccttct
    17941 ggatcaccaa ccagcagacg atgaccgccc gcaataccat gctgacggta ttttcgcgcc
    18001 agaccgacaa gcagtactac atgaaccagc aacgtacgca gagtgcgcgt gaatacgaca
    18061 ccaacgtgct gaagccgttc caggatgtgc tgaatgaccc tgcgccgaag aaactgatca
    18121 tcgttcatct gctgggtacg catatcaaat acaaataccg ctacccggaa aatcagggca
    18181 agtttgatgg caataccgat catgttccgc caggattaag cgcagaagag ctggaatcat
    18241 ataacgatta tgacaacgct aacctgtata acgatcatgt ggttgccagc ctgattaaag
    18301 actttaaagc ggcagacccg aacggattcc tggtttactt ctctgaccac ggtgaagagg
    18361 tttacgacac gccgccgcac aaaactcagg ggcgtaacga agacaacccg acgcgccaca
    18421 tgtacaccat tccgttcctg ctgtggacgt cggaaaaatg gcaagcgact catccccgtg
    18481 atttctcaca ggatgtcgat cgtaaataca gcctggcgga actgatccac acctggtcag
    18541 atttggcggg cttatcttac gacggttacg atccaacccg ttcagtggtg aatccgcagt
    18601 tcaaagaaac tacccgctgg attggtaacc cgtacaagaa aaacgcgctg atcgattacg
    18661 acactctgcc gtatggcgac caggtaggta atcagtaatt atcagccagg cgctatttgc
    18721 cggatgcgac gcttgacgcg tcttatccgg cctacagatc gcggcggtag gctggataag
    18781 gcgtttacgc cacatccggc aatacaactg ccgcaatgtt tacatcgaac tcccctcagg
    18841 ccacactttt caggtggcct tttttaataa tgccagttac tgttttcccg tctacatacc
    18901 taagggaata acatgtatca cgacgtcagc tatctgctct cccgcctgat caacggcccg
    18961 ctgtccctgc gccagattta ctttgccagc agtaacggcc cggtgcccga tcttgcgtat
    19021 caggtcgatt ttccacggct ggaaattgtg ctggaaggtg agtttgttga taccggcgct
    19081 ggagcaacgt tagttcccgg cgatgtgctg tacgttgccg ctggtggctg gaatttccca
    19141 caatggaaaa cacccgctac cacctttagc gtgctgtttg gcaaacagca actcggcttc
    19201 agcgtcgtgc aatgggatgg caaacaatat caaaatctgg cgaagcaaca cgtcgcccga
    19261 cgcggcccac gtataggttc ttttctgcta caaacgctca atgaaatgca aatgcagccg
    19321 caggagcagc aaacggcaag gcttatcgta gccagcctgc ttagccactg ccgcgatttg
    19381 ctcggcagcc aaatccagac cgcctcacgc agccaggcac tatttgaagc tattcgcgat
    19441 tatatcgacg aacgctatgc ctccgcgctt acccgcgaat ctgtcgcaca ggcattctat
    19501 atttcaccaa actatctctc gcacctgttt caaaaaacgg gggccattgg ttttaacgaa
    19561 tacctgaatc acacgcgact ggagcacgct aagacgttat tgaaaggcta tgacctgaag
    19621 gtaaaagaag tggcgcacgc ctgcggcttt gtcgacagca actacttctg ccgtctgttt
    19681 cgtaaaaaca ccgaacgctc gccgtcggaa tatcgccggc agtaccacag ccaactgaca
    19741 gaaaaaccga ctactccaga ataagatggg tttgctgcgg cgcagaaagc actttgcgca
    19801 ccgcgctcat tacccgctgc ggctcacgca ggaatgcgta gatgctgcat tgcacatagc
    19861 ggcaatgttc aaatcgctcg gcaccggcaa gctcgatatc cgtaatcaac agagcaacat
    19921 ccgcccgacg gatatcctcg tccgctaaac gattctccgt tcccagcgcg ccctgagttt
    19981 caatgctgac tccccacttc tctaacaggc acaacttttc cagccgttcc gccgccatat
    20041 aagtatgcgc cacgccactg acgcaggcgg ttactgccac caggtatgcc attttaacct
    20101 cccacggtaa cctgaaatcc ggcccgttct gccatttcgc gcatcgttgc cacatcggct
    20161 gacgacggcg caggcacctc tttcatcgac catgttttcc ccagcaggcg gtatttcggt
    20221 tcgccgtact gatgaaacgg taacagatgg atctgcctga tattcagcgg gatcagcaca
    20281 tccagcgcct gctgcatatt ctcccggctg agcgtgaaac cagggatcag cggtaaacgc
    20341 gggatcacgt tgacgccctc actcaccagc aaacgcagat tctccagcac gcgtggcagg
    20401 ttcatcttca ccacatcccg cgcctgagtc gcgtccatga tttttaaatc gaacaacact
    20461 tcatcgcaca atttcgccag cggtaacagc ttgctggctg gcgcgtctcc ggcagtttca
    20521 atggcacatg agacaccaca cagctgcagt cgctgtaaaa aacgggtagc aaactccgcc
    20581 tgcattaaca cttcgccgcc agaaagcgtg acgccgccgc cggacgtgcg aaaaaaaatg
    20641 tcatctttca tcacttcccg ttccagagcg tcaaggctga tatcgcgacc aatccgttca
    20701 aacgccccgg aggggcattc atccgcatca cgcaaacatt tcgcacagtg cagacatttc
    20761 gcctctctgc gtaccgtctg gattttgccg gagatcgact ccggattagc acaccacggg
    20821 caaagatgcg gacagccttt aaaaaagacc accgtacgaa tgccctcacc gtcattcagt
    20881 gaataacgct gaatgttgaa aatgcgcgcc acatcattgc ggcgcgtttc cacaacgtta
    20941 cagctgatgc gctgtccggc ggatgatgtc atcctggatc tccttcgaca gttcgacaaa
    21001 gaaggcgctg tatccggcaa cgcgcaccac cagcccggca taatcttgtg ggcgctgttg
    21061 cgcttcccgc aacgtgtcgg cgttcaccac gttaaactga atatgttgta acttaagctg
    21121 ggtaaacgcc cgtaagaagt cggccagttt gcgtaatccc gcttcacctt ccagggtcgc
    21181 cggagtgaat ttcacgttca gcaatgtacc gttagacagc agtgtgttat cgagcttact
    21241 gactgacttc agtaccgccg ttggcccttg tgcgtcctga cccagcatag gtgacaagcc
    21301 gccgtctgcc agctgttctc cggcaaaacg accgtctggc gtcgcgccaa ccaccgatcc
    21361 caacggaacg tgagcagaaa cggtatacga tcccggcgtg aagtagccgc cgcgcgggtt
    21421 ctggtatttt tccacttctt tgcagtagtg gcgcaacagt tcggcgctaa tgttatccac
    21481 ctcgtcgata tcgttaccgt atttctcaaa gcggttaatt aagcgagcgc ggactttttc
    21541 gccttctggc gttgcaaagt tggcttttaa taccgacagc aattcgtcaa aacttaaacg
    21601 ctgttgatca aaaaccatcc ctttcaacgc atggagagaa tcgctcaggt tggcgatacc
    21661 gatcccctgt acgccggaga agttataacg cgcgccgcca tcggtaatat cgcggccttt
    21721 ttccagacaa tcgctgataa aagacgagag cagcggtaca ggtgcccagt cgcgatggcc
    21781 gatatcgcaa atattactgc cttcaaccat cagggtgatg tagtggctga tcttggcacg
    21841 gatctgttcc agtaaacctt cataagtcag cgcggcattg ccttcatttt catgcaggca
    21901 gatttccatc actttcagca ggttaaacat cgcgatgtca tgcaagccgt aggttctgcc
    21961 gggaatagat aattccacac agcccactac ggaatagtcg cgcgcatctt ccagcgaaac
    22021 gccacggttg aggaacgctg gcaccaccac ttcatcgtta aagatttgcg gaataccggt
    22081 gccgaggcga atggtttcgg cggttttcat caggaacggc gtgtcgatca aggcgttagt
    22141 gcgcacgccg aggttcggtt gcggtaattg cacgctttga taggcgtcaa ggcaaaggaa
    22201 cgaaagcacg ttcaccgcgc tacgtccgtt ctcggttaac ccgccgagca gtgcggtata
    22261 gccggtcggg aaaccggcga aataacgcgc gctgctggtg gagcgcaaca gcacgatgtc
    22321 gttgcatttc acccataaag attcgagcag ttctttcagg aacgccgcat cttcgccctg
    22381 ggttaatgat gtctgataga acggcaacat atactggtcg aagcgcccca acgatagcga
    22441 actggcgttg gattcgtatt gcagaatgat gttcatgtac cagaataact ggcacgcctg
    22501 ccagaacgtc tgcggcttat gttgcgcgtt atggcgggag atctccgcaa tagtcagcag
    22561 ctcttcgcga cgctgggcat ctgtgcagtt tgccgccatc gtttccgcca gttcggcgta
    22621 acgcaaaatg tgtttctgcg aggcttccag cagtaacagc gctgcctgat aaaagtgatt
    22681 ctccggctgt tgctgacaat gttgctgcat ctgtgctacc agctccccca gcccgtgatt
    22741 cagcaggcgt gggtaatcaa taataatgtg cccctggcct ttatctgtct ggttgatgct
    22801 gaaaatctgc gtgctggtcg cggcttttac ttcatctgtc atctgcccgt tgatgaaatc
    22861 tttcatcgaa cgtttttccc agtacgggaa caactcttcg cggtagatac gtttatcttc
    22921 ttcgctgata gcaaagcggt cctgcggacg cgtcgggaat tgatccagct ctttcagcag
    22981 ccagtaaggg tccatttccg gcgacataat cccggcgcgc ggttttacgg tgcggttacc
    23041 ggcaatcagt tcttcatcac gaatcgaaat ttcaacatgt tcaaggatat acgctgttgc
    23101 tttcgcccgg cgcaatatca ccggttcgcc ttcggtttgc cgatggctgg cggtataaag
    23161 cagcgcccgc tccagcgaga tttcacgggt attggcaaac agtgcagttt tgaggcgaga
    23221 gatacgattc gtcatgagga actcctgtgg gaaagcgaac ccgcccttac gggcgggata
    23281 agaacttaag cggtttgcgc caggtgagct tcaattttgc tcataatggc atcagcacgt
    23341 tttaccgcat cgctgatgtt gacgcgcacg atggtcttgc cagcaaaacg ctcttcaaac
    23401 ttgatgccga tatctttagt cagaatcacc atatcggcgc tcgccacgtc ttccgcagtc
    23461 agttcatttt ccagaccaat tgagccctgg gtttctactt tcacttccca gcctttcgct
    23521 ttcgcggcac tttccagcgc ttctgctgcc atataggtat gggcaacacc tgaaggacat
    23581 gcggttactg caataatttt cgtcatggct tgttcctcaa ttaattaatt tcaaaatcca
    23641 aatccaggtc gtcttctttt tcatcagtcg aagacccatt tttacgcgcc agacttttca
    23701 gcacgttcac acaaacagcc gtcaccactg ctccgacagc cactgcggcg atataaccca
    23761 gcttgccttc aaccaccggc agtacaatca gaccacccca gcctgcatag cactgcgcac
    23821 cgaccagcgc cgcagttatc gcaccacaaa cagaaccaac catgatggaa ggaatgacac
    23881 gcagcggatc ggcagcggcg aaaggaatcg ccccttcagt aaccccaacg caccccatca
    23941 ccagcgccgc tttaccagtt tcgcgctctt ctgcggagaa atttttacga ccaatcagcg
    24001 tcgccagccc catccccagc ggtggaacac aaatcccaac agcggcaata gccaccacgg
    24061 tataaacacc ctgagcaacg caaatcagca tgaaggcata ggccactttg ttaaccggac
    24121 cgcccatatc gaacgccagc atcagaccca tgatcaccgc cagcataaca atgctgccct
    24181 gctgcatccc ctgaagccac tgagtcaggc tgttggtcaa cgcccctaca ggctcgccca
    24241 agccccacat catgatgcct gcggtaatca gtgtgccgac gataggaatg atgaagatag
    24301 gcatcaccga gcgcagaact ttatgcaccg gaattttctt caggtaatgc accacgatgc
    24361 cgccgataat cccggcgatc agcgcaccaa agaagcccgc accaaagctg ttaccaaccc
    24421 aggcaccgat agcgcacgga gccagcgcag aacgctctgc aatggagtaa ccaatgtaag
    24481 cggcgaggaa aggcaccatc agcgtcaaac ccgcaacgcc gatatcaaac agttttttca
    24541 gattcggatc ggctacggca tccggcactg cgcctttgcc atacaacatg acggaaaccg
    24601 ccagcaaaat accgcccgat accacgaagg gaatcatgtg tgaaacgccc gtcattaaat
    24661 gctgacgggt atttttcagg atctgcacca actcattcat aagctgctcc cgggcttgca
    24721 aaagcccatg tccatatttt tgatggagga aacaataggc aatcgcaggc ggagcaaaca
    24781 gtggataaaa aggccattta ctggactttt gtaatatcag tacaaaaatg cgatccgcct
    24841 cataacttgc gataatccgg aagcatgccg caaaacggcg tcttgtgaga cgcgtcgcaa
    24901 attgacggtt acattacatt tgtccagctt ttggcagatt tgtcacatgg caggccgttg
    24961 ccgtgcgctc ttatcctgta aacagaaaac cgtaccggga gagaggcaat ggccctgatt
    25021 gtggaattta tttgtgagct acctaacggc gtacatgcac gtccggcaag ccacgttgaa
    25081 acgctgtgta atactttttc atcacaaatt gagtggcata acctgcgcac tgaccgtaaa
    25141 ggcaacgcca aaagcgccct ggcgctgatt ggcaccgaca cgctggtggg cgataattgc
    25201 cagttactga tttccggggc cgacgaacag gaagcgcacc agcgtttaag ccaatggctg
    25261 cgcgatgaat tcccccactg cgatgcgccg ctggcggaag ttaaatctga cgaactggaa
    25321 ccactgccgg tttcattgac caatctgaat ccgcaaatta tccgcgcccg caccgtgtgc
    25381 agcggtagcg caggcggcat tctgacgccg atctcttctt tagatctcaa tgcgctgagt
    25441 aatcttcccg ctgccaaagg cgttgacgcc gaacaatccg cactggaaaa cggcctgacg
    25501 ctggtactga aaaacattga gtttcgtctg ctggatagcg acggtgctac cagcgcgatt
    25561 ctggaagcgc accgatccct ggctggcgat acttccctgc gcgaacattt actggcaggc
    25621 gtcagcgccg gattaagctg cgccgaagcg attgtcgcca gtgcgaatca cttttgcgaa
    25681 gagttcgccc gttccagcag cagctacctg caagaacgtg ccctggacgt acgcgacgtc
    25741 tgcttccagt tactccagca aatctacggt gagcaacgct tcccggcacc gggcaaactg
    25801 acgcagcccg ccatttgtat ggctgatgaa ctgactccca gccagttcct cgaactggat
    25861 aaaaatcacc tcaaaggtct gttactgaaa agtggcggca ccacctcaca taccgtaatt
    25921 cttgcccgtt cgttcaacat tccgacactg gttggtgtgg atattgatgc cctcactccg
    25981 tggcagcatc aaacgattta tatcgacggc aacgctgggg cgattgtggt tgagccaggg
    26041 gaagccgtag ctcgttatta tcagcaagaa gcccgcgtac aggacgccct tcgtgagcaa
    26101 cagcgtgtct ggctgaccca acaagcccgt accgctgacg gtatccgtat tgaaattgcc
    26161 gctaacatcg ctcactccgt ggaagcgcag gccgcattcg gcaatggtgc ggaaggcgtt
    26221 ggtttgttcc gcactgaaat gctctatatg gatcgcacca gtgcaccggg tgaaagcgag
    26281 ctgtacaaca ttttttgtca ggcgctggag tctgccaacg gacgcagcat tattgtgcgc
    26341 actatggaca ttggcggtga taaacccgtt gattatctga acattccggc agaagctaac
    26401 ccgttcctcg gttatcgcgc ggtgcgtatt tatgaagaat acgcgtcgtt gtttaccaca
    26461 caactacggt caatcctgcg cgcctctgct cacggcagcc tgaaaatcat gatcccgatg
    26521 atctcctcaa tggaagagat cttatgggtg aaagaaaaac tggcggaagc caaacagcaa
    26581 ctgcgtaacg aacacattcc gtttgatgag aagatccagc tcggcattat gctggaagtg
    26641 ccgtcggtga tgttcatcat cgatcaatgc tgcgaagaga ttgatttctt tagtattggt
    26701 agtaatgacc tgacgcaata tctgctggcg gtggatcgcg ataacgctaa ggttactcgt
    26761 cactacaaca gcctgaatcc ggcattcttg cgggcgctcg attacgccgt gcaggcggtg
    26821 catcgccagg gcaaatggat tggtctgtgc ggtgagctgg gagcgaaagg ttccgtgctg
    26881 ccgttgctgg tcggtttagg gctggatgaa ctcagcatga gcgcaccgtc aattccggcg
    26941 gcgaaagcgc gaatggcgca acttgatagc cgtgagtgcc gccagttgct caaccaggca
    27001 atggcctgcc gtacttcgct ggaagtggaa catctgctgg cgcaattccg catgacccaa
    27061 caggacgcac cgctggtcac cgccgagtgc atcacgctgg aaagtgactg gcgcagcaaa
    27121 gaagaagtgc tcaaaggcat gaccgataac ctgctgctgg cgggccgctg ccgctatccg
    27181 cgtaaactgg aagccgactt atgggcgcgc gaggccgttt tctctaccgg tctgggcttt
    27241 agttttgcca ttccccacag caaatcagaa cacattgagc aatccaccat cagcgtagcg
    27301 cgtctgcaag cgccggtgcg ctggggcgat gatgaagcgc aattcatcat tatgttaacc
    27361 ctgaacaaac acgctgcggg cgatcagcat atgcgcattt tctcgcgcct cgctcgccgc
    27421 atcatgcacg aagaattccg taacgcgctg gttaacgccg cctctgccga cgctatcgcc
    27481 agcctgctgc aacatgaact ggaactgtaa aaggaaacat catggaactg tatctggaca
    27541 ccgctaacgt cgcagaagtc gaacgtctgg cacgcatatt ccccattgcc ggggtgacaa
    27601 ctaacccgag cattatcgct gccagcaagg agtccatctg ggaagtgctg ccgcgtctgc
    27661 aaaaagcgat tggtgatgag ggcattctgt ttgctcagac tatgagtcgt gacgcgcagg
    27721 gtatggtgga agaagcgaag cgcctgcgcg acgccattcc gggcattgtg gtgaaaatcc
    27781 cggtgacttc cgaaggtctg gccgccatta agttgctgaa aaaagagggt attactacac
    27841 ttggcaccgc tgtatatagc gccgcacaag ggttattagc cgcactggca ggggcaaaat
    27901 acgttgctcc gtatgttaac cgcgtagatg cccagggcgg ggacggcatt cgtacggttc
    27961 aggagctgca aacgctgtta gaaatgcacg cgccagaaag catggtgctg gcggccagct
    28021 ttaaaacgcc gcgtcaggcg ctggactgtt tactggcagg atgtgaatcc atcaccctgc
    28081 ccttagatgt agcgcaacaa atgctcaaca cccctgcggt agagtcagct atagagaagt
    28141 tcgaacacga ctggaatgcc gcatttggca ctactcatct ctaaaggagc aattatggac
    28201 cgcattattc aatcaccggg taaatacatc cagggcgctg atgtgattaa tcgtctgggc
    28261 gaatacctga agccgctggc agaacgctgg ttagtggtgg gtgacaaatt tgttttaggt
    28321 tttgctcaat ccactgtcga gaaaagcttt aaagatgctg gactggtagt agaaattgcg
    28381 ccgtttggcg gtgaatgttc gcaaaatgag atcgaccgtc tgcgtggcat cgcggagact
    28441 gcgcagtgtg gcgcaattct cggtatcggt ggcggaaaaa ccctcgatac tgccaaagca
    28501 ctggcacatt tcatgggtgt tccggtagcg atcgcaccga ctatcgcctc taccgatgca
    28561 ccgtgcagcg cattgtctgt tatctacacc gatgagggtg agtttgaccg ctatctgctg
    28621 ttgccaaata acccgaatat ggtcattgtc gacaccaaaa tcgtcgctgg cgcacctgca
    28681 cgtctgttag cggcgggtat cggcgatgcg ctggcaacct ggtttgaagc acgcgcctgt
    28741 tcccgtagcg gcgctaccac tatggcgggc ggcaagtgta cccaggcggc gctggcactg
    28801 gcagaactgt gctacaacac tctgctggaa gaaggcgaaa aagcgatgct tgctgccgaa
    28861 cagcatgtag tgactccggc gctggagcgc gtgattgaag cgaacaccta tttaagcggt
    28921 gtaggctttg aaagtggtgg tctggctgcg gcgcacgcag tgcataacgg cctgaccgct
    28981 atcccggacg cgcatcacta ttatcacggt gaaaaagtgg catttggtac gctgacgcag
    29041 ctggttctgg aaaacgcacc ggttgaggaa atcgaaaccg tagctgcact tagccatgcg
    29101 gtaggtttgc caataactct cgctcaactg gatattaaag aagatgtccc ggcgaaaatg
    29161 cgaattgtgg cagaagcggc atgtgcagaa ggtgaaacca tccacaacat gcctggcggc
    29221 gcgacgccag atcaggttta cgccgctctg ctggtagccg accagtacgg tcagcgtttc
    29281 ctgcaagagt gggaataacc tactccaaac tcccggcttg tccgggagtt tgaacgcaaa
    29341 attgcctgat gcgctacgct tatcaggcct acgcaatctc tgcaatatat tgaatttgcg
    29401 tgcttttgta ggccggataa ggcgttcact ccgcatccgg cactctgtgc cagtaatctg
    29461 aaactcccac gttgttcagg aattttttat ccgcttctgg acattttctc tacagaacaa
    29521 tcgttagccc ggaaggtcga atctgtgact cttattttca cggacgaacc agatgaaagc
    29581 ttcactggcg ctgctcagcc tgctaacggc atttaccagc cactccttaa aatctcccgc
    29641 cgttccacca accgtggtac aaatccaggc caataccaac cttgccatcg cagacggtgc
    29701 cagacagcaa attggcagca cgctatttta cgatccggcg tatgtgcagc ttacttatcc
    29761 tggcggtgat gttccgcaag aacgcggtgt atgttccgat gtggtgatcc gcgcattgcg
    29821 cagccagaag gtcgatttgc agaaactggt tcactaagat atggcgaaga attttgctga
    29881 gtacccgcaa aaatggaagt taaagcgccc ggacagcaac atcgatcacc gtcgggtgcc
    29941 taatctggaa acctggttta gccgccatga taaaacacgc cccaccagca agaaccccag
    30001 tgactatcaa gcgggcgata ttgtctcctg gcgactggat aacgggctgg cacatattgg
    30061 ggtggtttca gatggcttcg cccgcgacgg tacgccgctg gtgatacata acattggcgc
    30121 aggcgcgcag gaagaagatg tgctgtttaa ctggcggatg gtggggcatt atcgttattt
    30181 tgttaaataa gagatcgccc cacatgaaga aaaaattcag atccttttta cactgacggc
    30241 ttcttttttc ttacggctca ccagcgccag tgccagcaca atcagcacaa taccgctacc
    30301 ctcaaccgcg ccaggattct caccgagcag ccaccaggaa aagagtacgc cgcaaacggg
    30361 aacggccagt gtgcttaagc tggcaatact ggcaggcaag tttttcaata caaacaacca
    30421 taagctccac gccagcgccg tcgccagaat cgcactgtag gccagcgccc agaacacggt
    30481 gggttgccag tcaatttcac gttgcggtac cagtaaagcg accacactca tcaccagcgc
    30541 cgcatacagc atctgccagg atgttaacga caataaatcc acgcgcggat gacgggcgta
    30601 aaggcgttta gcgacaatgg cgctcgcccc ccaactgaca ccggagagga tcgccagcat
    30661 ggcgcttttc atcgaagaga aatcgagttg ccacggctgc aacaccaaaa ataaaccgaa
    30721 agcggcaatc agaatcgcga aatattgccc acgtcgcagg cgttcaccga gaaacaacgc
    30781 ggcgaaaatc actacccaga acggcatggt atagctcagg atcgctactt tccccgctcc
    30841 gccgctgacc agcgcccact gcgccagacc aaccatccca caggtttgta acagggcaat
    30901 gactaaggtg taattaaacg gcgtcgggcg cattccgcga ccacgtaata aaaggacgat
    30961 gaataaaacg agagcgccga aaatgcagcg taaggcggtg aagtcgaagg caccgatgta
    31021 gctggtgact tgcttcatga aaatccagct ataactccag ataagtgtga gcacaaccag
    31081 gccactgatt gccagtgggt tgctctttcc tgcggcagac atgagagatc cagtgtgtag
    31141 ttttcctgtg gacactatac gccggtaaag aaacttcagc gactgcctga aaggcagtcg
    31201 ctgaagaagg tcagattaca gcatgtcgaa acggtcgagg ttcatcactt tcacccatgc
    31261 cgccacgaag tctttaacaa acttctcgtg ggcatcgctg ctggcgtaaa cttcagccac
    31321 cgcacgcagg actgagttag aaccaaatac cagatccgca cggctggctg tgtatttcac
    31381 ttcgccagtt tcacggtcac ggccttcgaa cagctctttc gattcgtccg ccgctttcca
    31441 ctcgtaacgc atatccagca aattcacgaa gaagtcattg ctcaatacgc caacgcggtc
    31501 agtgaagacg ccgtttttgc tgccatcgaa gttggcaccc agtacgcgca tcccgcccac
    31561 cagcgcagtc atttccggcg cggtcagcgt cagttgctgg gctttgtcga tcagcagtga
    31621 ctcggtggtg gaaacatcca gacgagcgcg atagttacgg aaaccgtcag caattggctc
    31681 cagcagttcg aacatctcaa tgtcagtctg atcctgacgc gcatcaacgc gacccggcgc
    31741 aaacggtaca tgaatgctca aacctgcggc gcttgcggct ttctcaacac caaccacacc
    31801 agccagcacg atgatatccg ccagcgaggc tttaccagac tctttctgga ttttctccag
    31861 aacaggcaga gcacgaacgg ctgcggcgtt cacatcccag tcgcgctgcg gcattaatgc
    31921 cagacgcgca ccgttggcac caccgcgttt gtcgccacca cggaaggtag aagcagatgc
    31981 ccaggccacc gataccagct cactaacaga cagaccagaa tccgcaatcg cgaatttcag
    32041 atcgataatg tcctgctcgg tcgggttgta gatcggctgc ggcagcggat cttgccagat
    32101 cagatcttct ttcggcactt ccggcccgat gtagcgagat ttcggcccca tatccctgtg
    32161 cgtcagtttg aaccaggcac gggcaaaggc ttcgttgaac gcctgcggat cgttgaggaa
    32221 acgacgagag atcttctcga actcaggatc aaaacgcagc gtcaggtcgg tcaccagcat
    32281 tgtcggttta cgtttcttcg acggatcaaa cggatccggg ataatttccg gtgcgtctac
    32341 cgcttcgaac tggattgcgc cagccgggct gcgggtctgt acccactcat acttgaacag
    32401 gttctcgaag aaatagttgc tccactgggt cggcgtctgg gtccagacta cttccagacc
    32461 agaggtaatg gcatctgcgc caacgccgct gccgtaagtg ctcgcccaac ctaaaccttg
    32521 ttcttcaatc ggtgcagctt ctggatcagg acctacattt gatgtcggac cggcaccgtg
    32581 ggttttaccc agcgtatgac cacccgcaat cagcgccacg gtttcttcgt cgttcatgcc
    32641 catgttgccg aaggtcgcgc ggatagctgc tgccgcagaa agcggttcgc cgctgtgatc
    32701 cgggccttcc gggttaacgt aaatcagacc catctcggtt gcacccagcg gtgctttcgc
    32761 cagcgcttcc ggatgacggt gagtcagcca ggctttttca tcaccccagt taacatccag
    32821 atccggttcc cagacgtctt cacgaccggc accaaaaccg aaggtacgga agccggagtt
    32881 ttctagcgcc acgttacccg cgaggataaa caggtcggcc caggagattt tctgaccata
    32941 tttctgtttg attggccaca acaggcgacg cgctttatcg aggcttacgt tatccggcca
    33001 ggagttcagc ggtgcaaaac gttgctgacc acgacccgcg ccaccgcgtc catcgattga
    33061 acggtaagtc cccgcgccgt gccaggccat acgaataaac agaccggcgt aactgcccca
    33121 gtcggctggc caccacggtt gagattctgt caacagggct ttcagatctt ttttcaggcc
    33181 gtagtaatct aatttgctga attctttgcg gtagtcaaag tcctcaccca gtgggttaga
    33241 acgattagaa tgttggttta acaggtcaac acgaagttga tttggccacc agtcgcgagt
    33301 ggttgtgccc gcccccgcac tctggtcgtg accgccctga tggaacgggc atttgccagt
    33361 ggctgtggtg ttatggatat cgtctgacgt gctcatcaat gtgctcccct ctacagtgtt
    33421 accgttacga tacacagcgt tagagagaag ttataattga attaatccac ggatgcgata
    33481 gttgagatct tacatattgt tggttaaaga gatgtagatc aaattgatct taattaagct
    33541 tttttgatta tgtccgaatt cggacaaatg ctttataaaa aagggtttta gcttcatatc
    33601 cttcaagtaa tgagggagaa aacaaggctg ataaccttat tttcccgccc tcatttcgag
    33661 gcagcatttt gtgctctgtt taaaatttgt gatcactgtg tgattttcac aaaagccaca
    33721 ctatttataa accaggtcga acccccagcg tatggcaaat cgcgtaactc atttcagcac
    33781 ggttaagcgt atagaagtgg aaatctttca ctccttcacg gcttaaaatc ttcaccatat
    33841 ccatggcaat attcgcgcca accagtttgc gggtttcggc atcatcatcc agaccgtcga
    33901 acatttgcgc catccacgcc ggaatacgca cgttggtcat atcggcaaat ttcttcgcct
    33961 gtttaaagtt agataccggc aaaattcccg gaataatttc cacatcaatg cccgccgata
    34021 cacagcggtc acgaaaacgc aggtagcttt cgacatcgaa gaagaactga gtaatcgcgc
    34081 ggttggctcc ggcatccact ttgcgtttca gattaagcaa atccgcctga gcgctttttg
    34141 cttccgggtg aacttccgga tacgccgcca cggagatatc gaaatctgcc acttctttta
    34201 acagcgtcac caggtcagaa gcatacattt ctggcttacc acttcccggc ggcagatcgc
    34261 cacgcagcgc cacgatatga cgaataccgt tattccagta gtcgcgtgca atggtgcgca
    34321 gctcgtcgtg cgtcgcatca atgcaagtaa gatgcggtgc cgcttccaga ccagtgcgat
    34381 ctttaatgcc tttaataatg ctgtgcgtac ggtcgcgctc gccggagttc gcgccatagg
    34441 tcaccgatac aaacttcggt ttcaggctgc taaggcgatc gatggagttc cacagggtct
    34501 gctccatttc actggtacgc ggcgggaaaa actcgaacga aacgttaatc tgcccctgga
    34561 cttctgccag gctctgattc agggcatccc gctggctggc gtgaaaaaag ctcatacctt
    34621 acctcatcaa tcgcttgtag ttatatgttg tgttgtgcac atctatccgt ttagacgtcc
    34681 agatgtaaag atgaaggaaa agccgaaggg cgtcaaccga aaaatgacca atgatggtga
    34741 ggaaaaatca gggaagatga aaaaacttca ggatggtaag aaaaagaaaa tccggtatgc
    34801 aaagcaaacc ggactgcaaa tataaactaa ccatgtactt attgcttctt gccggattcg
    34861 tcgtaaacgc ttaatccggc ctaatcctat gataattcaa tatatttcat tagaaaccat
    34921 aaacccgaaa acatgagtac cgggcattat taaatttctg aaattacaac aactgtgcca
    34981 gccggttgat atccgactga atcgccccgg cggtgacgtc gcgccccgcg ccaggcccac
    35041 ggatcaccag cgggttgtcg cgataccagc ggctttcgat ggcaaagacg ttatcgcacg
    35101 gcagcagtga tgccagcgga tggtcttcac gcaccgcctc cacgcccaca cgcgctttgc
    35161 cgttggcatc gaaacgcgcc acgtagcgta gcaccagccc catttcgcgg gccgcttcca
    35221 gccgttgcac catctgctcg ttaagttcat cgccattttc aaagaaatgg tcgatgctgc
    35281 cgccttcgca atgagcaggc accagcgatt ccacacgtac ctggtccggt tcaatgttgt
    35341 aacccgcttc acgcgccaga attaccagct tgcgcattac gtctttgccg gagaggtcgt
    35401 cacgcggatc aggctcggtt aagccctgct gccacgcctg atccaccagc tcggtaaacg
    35461 gcacgctacc gtcgaattgc aggaacagcc aggagagcgt gccggagaag atcccgctga
    35521 tcgacaaaat agtatcgccg ctgtcgatca gatcgcgcac ggtgtggttg atcggcaagc
    35581 ccgcaccgac ggtggaattg tacagccagt gacgcccggt tttttcgaag gcgtcgtgga
    35641 tctggcgata tttattgctg tcgctggctc ccgccagttt gttggcgctg ataacgtgga
    35701 aaccgtggct ggcgaaatca agatactgat cagcaagctg ctggctggcg gtaacgtcca
    35761 gcaccactaa atcatcatac ggatgggcgc gcatccacag gaacaacgac tcttcatcct
    35821 gctcaaccgc ttcatcgttg aagaaggcta acgcgcggct ggcgtccagc ccgtcatagc
    35881 tcaacaggct gcggcggctg tccaccacac ctgccagcac aaactcaaag ccggtacgtg
    35941 ccgaaagcgt gctctgctca cgggcgaaca gttccagcca acgggaaccg atattgccct
    36001 taccgaacaa taccaggccg atgcgttttt ctgcgcggaa gacggactga tgcagcccct
    36061 gaatcaggct ttcggtcggg ccggtgcgca gtactgccac caggctgatg ccgtcatcgg
    36121 actgccaggt aaattcgacc ggctggcctt tcagttgctg ccagaagcgg tggcaatgca
    36181 gcgggttacg ggtgacgcct gcaccgacca tcgccaccag cgccagcccc tgacgcaggc
    36241 gcagttcgcc aggtaatccc gcttcgtcga ggattttcag cgcactgtcg gccacttctg
    36301 aggtgtagca aaattgcagc aactggcgat cgttatgtac gccaaccgcc agcgggcgta
    36361 cctgcgcgcg tttcaggatt tggtcgatct ctttatgcgc cagtttgaaa tcctgactgg
    36421 cgggcacctg aaactcaatc aaacagacat catcgtggct ggtgacaata cgcgcaccag
    36481 taccggaggc cagcacgcgt tcaatgcgcg tggaaccttg atccggcgtg tagctacagc
    36541 gcagttgcag gtcgatttcg ctgccagaaa ccggctgtaa agtacgggcg tgaagaacgg
    36601 gagccgccag gcgcgccagt tcgctggcct catccagacg cagcaacggc agcaggcagg
    36661 catctttcac tttacgcggg tcggcactgt ataccccggc gacgtcgctc cagatggtta
    36721 cgcgagaaac acccgccagc gcaccgattt gtgtcgcgga atagtcggaa ccgttacgcc
    36781 ccagcagcac cgtttcaccg gcgttgttgc ggctgataaa tccggtcacc accagacgtt
    36841 tgcccggatg ttgcaccagc agctgttgca gcaacgggta agaaagccct tcatcaacct
    36901 gcggttgtgc ggcgcgttca gcgcgtaaaa actcgcgggc atcaagccag gccgctggca
    36961 gcccttgttg attaagtacc gcagacatca ggcgtgccga ccatacttcc ccgtggccca
    37021 ccacttccgc atacactgcg tcgttaatac cgctgtcgag cagcgccgtc aggcgctcaa
    37081 ggtcgctgac aaaagcgcta atgaggctat cggcttcttc agcgggtagc agaccgctaa
    37141 tcagatcaca ctgatagcga cgcagcgttt gttgaacctg atgcgcagag agacgatcgg
    37201 tctggcttag tttcaaccag ttaatcaact ggttagtggt gctaccggca gcggaaacca
    37261 ccatcatatc gtcaggctga gagtactccg ccataatgcc cgcgacacgc aaataacact
    37321 tcacatcagc cagactactg ccaccaaatt tatgcagctg acgacctttc gcccctgcct
    37381 gcgcaatcac actcattttt accccttgtt tgcagcccgg aagccatttt ccaggtcggc
    37441 aattaaatct tcgccatctt caataccggt ggagatacgc agcagcgtct cggagatccc
    37501 ggcggcagca cgcgcttctg gtgccatgcc tgcatgtgtc atggttgcgg cgtgagagat
    37561 taaactttcc actcccccta atgattccgc cagcgtaaac aacgacagcc cgcccaggaa
    37621 acgacgcagc gtctgctcat cgccatccag ttcaaaactc aacattgcgc caaagccttt
    37681 ttgctggcgc gcggcaattt catgcccctg attttccggc agcgacgggt gatacagttt
    37741 tttcaccaac ggctgggttt gcagatattt cacaatcgcc tgcgcgttgc gctgggccaa
    37801 ctccatgcgc ggcaccagcg ttcgcaaccc gcgtagcagc agatagctgt caaacgcgcc
    37861 gcccgtcacg ccaatattgt ttgcccacca ggcaagttca gtgacaacgt ccgggtcttt
    37921 agcaatcacc acgccagcca ccacgtcaga gtgaccgttc agatatttcg tgcatgaatg
    37981 caacaccaga tcggcaccta atgccagcgg attttgtaat gccgggctta agaaggtgtt
    38041 atccaccacg ctcaccgccc cgacttccct agccagatgg cagattttcg caatatccac
    38101 gacgcgtaac aatggattac ttgggctttc taccagtacc agtttgggtt tttctgccag
    38161 cgctgcccgt aatgcctgtt catcgccttg atcaacaaac aacacgcgat agcaaccgcg
    38221 tttcgccagg ctgtcgaaca ggcgatagct accgccgtag cagtcgtgcg gcgcaaccag
    38281 cagatcgcct ggtttcaaaa agacggtcgt taccaggtga atcgcggaca tgccggtatt
    38341 agtaagtact gcaccagcac cgccttccag ttctgccagc gcacgctgaa ccacatcgcg
    38401 cgttgggttg ccgcgacgcg agtaatcatg cgcgcgcggt tcattaaatc cggtaaagtt
    38461 ataggtactg gaaagatgga tcggtgggac aacgcaacca tactgttcgt cgtcatttaa
    38521 cccgctacgc actgcgatgg tggcctgttt acgcgtcatg tgatgaagtt ccctgggctt
    38581 ggtcggtgaa atgtcaggca ccagagtaaa cattgtgtta atggacgtca atacatctgg
    38641 acatctaaac ttctttgcgt atagattgag caaatcccaa atagccgtta aaattatatg
    38701 cattatcacg ccgacaggtg cattacacga tgtcacggta acgcctgtac ggtaaactat
    38761 gcgggtttac ggtcagtacc cacataaatt gtgtggtctg gtctcaattt attgacgaag
    38821 aggattaagt atctcatggc tgaatggagc ggcgaatata tcagcccata cgctgagcac
    38881 ggcaagaaga gtgaacaagt caaaaagatt acggtttcca ttcctcttaa ggtgttaaaa
    38941 atcctcaccg atgaacgcac gcgtcgtcag gtgaacaacc tgcgtcacgc taccaacagc
    39001 gagctgctgt gcgaagcgtt tctgcatgcc tttaccgggc aacctttgcc ggatgatgcc
    39061 gatctgcgta aagagcgcag cgacgaaatc ccggaagcgg caaaagagat catgcgtgag
    39121 atggggatta acccggagac gtgggaatac taaagcaaaa aagagcggcg cggagtggaa
    39181 tcgcctgatg cgctacgctt atcaggccta cgtcatattg caatttattg aatttgcacg
    39241 aacttgtagg ccggataagg cgttcacgcc gcatccggca taaacaacga gcacgttgtc
    39301 tgcgacccac cgctttttat acatggacgt ttaactatga aaaacaggct gctgatcctc
    39361 agcctgctgg tttctgtacc tgcctttgcc tggcagccac aaaccggcga catcatcttt
    39421 cagatctctc gctcatcgca aagtaaagcg atccaactgg cgacccattc cgattatagc
    39481 cacaccggta tgctggtgat acgcaacaaa aagccctacg tttttgaagc ggtcggcccg
    39541 gtgaaataca ccccgctcaa gcagtggatc gcccatggcg aaaagggcaa atacgttgtt
    39601 cgccgcgttg aaggcggact gagtgttgaa caacagcaaa aactggcgca aacggcaaaa
    39661 cgttatctcg gtaaaccgta tgatttcagc ttctcatgga gcgacgatcg ccagtactgt
    39721 tcggaagtgg tgtggaaggt ttaccagaac gcgctgggaa tgcgcgtggg cgagcagcag
    39781 aagttgaaag agttcgatct cagcaacccg ctggtccagg ctaagctcaa agaacgctac
    39841 ggcaaaaata ttccgcttga ggaaacggta gtttcaccac aagccgtttt cgacgcgcca
    39901 caactcacca cagtcgccaa agagtggccg ctgttttcgt ggtaatggat gatgaaaaaa
    39961 ataattcccg ccgtagtctg tttgttgctt tgtagttgca cgacctttcc gcaagctgtc
    40021 gctccggtaa acggtgatgc ctccaattag ttgaattaag gatataatac tcgcttttaa
    40081 ggttgtttca tggtcacagt taaccttcat tgcccccgtt gccagtccgt tcaggtttac
    40141 cgtcacgggc agaacccaaa aagacatgat cgattccgcg gccgtgactg tcaccgggta
    40201 tttcagctca gttactgtta cgagccccgt aaaccgggag ttaaagacca aatcgctgaa
    40261 atgactttca acggtgccgg ggttcgcgat actgcccgta cgctgaaaat cggcattaat
    40321 acagtcatcc gaactttaaa aaactctcgc cacgaagaat aacgtcatcc ccggtcgctc
    40381 atgctgatgt ggcactcatc tgcaaactta gtcagcaatg gagctttgtc ggcagtaaag
    40441 cgcgacagca ctggctctgg tacgtgtaca acacgaaaac tggtggtgtt ctggcctaca
    40501 cttttggccc ccggactgac gaaacctgtc gtgaattgcg ggcgctgctt acccttttac
    40561 catcggcatg ttgaccactg acgaatgggg tagttacgct agagagttac cgaaggagaa
    40621 gcatctgact ggtaagattt ttactcagca cattgagcgt aacaatctga ccctgagaac
    40681 ccgaatcaaa cgtctggccc gcagaaccat ctgtttctcg cgttctgtag aacttcatga
    40741 aaaagtcatc ggtgctttta tcgaaaatat atgttctact aattggagtc atcacccttc
    40801 tgataagctt tccttggatg attaccagac tgaatacaca gccaaagatt tttacctcat
    40861 tctgctcttt tttctcaaat gacatatatt atatttt
//
LOCUS       DAPGUL010000032        40442 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.032, whole genome shotgun sequence.
ACCESSION   DAPGUL010000032 DAPGUL010000000
VERSION     DAPGUL010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 40442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40442
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.032"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            115..1479
                     /locus_tag="RHX21_001835"
     CDS             115..1479
                     /locus_tag="RHX21_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308508.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1987020.1"
                     /translation="MNDYKMTPGERRVTWGLGTVFSLRMLGMFMVLPVLTTYGMALQG
                     ASEALIGIAIGIYGLTQAVFQIPFGLLSDRIGRKPLIVGGLAVFAAGSVIAALSDSIW
                     GIILGRALQGSGAIAAAVMALLSDLTREQNRTKAMAFIGVSFGITFAIAMVLGPIITH
                     KLGLHALFWMIAILATTGIALTIWVVPNSSTHVLNRESGMVKGSFSKVLAEPRLLKLN
                     FGIMCLHMLLMSTFVALPGQLADAGFPAAEHWKVYLATMLIAFGSVVPFIIYAEVKRK
                     MKQVFVFCVGLIVVAEIVLWNAQTQFWQLVVGVQLFFVAFNLMEALLPSLISKESPAG
                     YKGTAMGVYSTSQFLGVAIGGSLGGWIDGMFDGQGVFLAGAMLAAVWLAVASTMKEPP
                     YVSSLRIEIPADIAANEALKVRLLETEGVKEVLIAEEEHSAYVKIDSKVTNRFEVEQA
                     IRQA"
     gene            complement(1607..2098)
                     /gene="yajQ"
                     /locus_tag="RHX21_001836"
     CDS             complement(1607..2098)
                     /gene="yajQ"
                     /locus_tag="RHX21_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414960.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide binding protein YajQ"
                     /protein_id="HDV1987021.1"
                     /translation="MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDA
                     SKTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLDVPENIVHSGKTWFVEAKLKQGI
                     ESATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAMVRGGDLGQPFQFKN
                     FRD"
     gene            2266..3177
                     /gene="panE"
                     /locus_tag="RHX21_001837"
     CDS             2266..3177
                     /gene="panE"
                     /locus_tag="RHX21_001837"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HDV1987022.1"
                     /translation="MKITVLGCGALGQLWLTALCKQGHEVQGWLRVPQPYCSVNLVET
                     DGAIFNESLTANDPDFLATSDLLLVTLKAWQVSDAVKSLASTLPVATPILLIHNGMGT
                     IEELQNIQQPLLMGTTTHAARRDGNVIIHVANGITHIGPARQQDGDYSYLADILQTVL
                     PDVAWHNNIRAELWRKLAVNCVINPLTAIWNCPNGELRHHPQEIMQICEEVAAVIERE
                     GHHTSAEDLRDYVMQVIDATAENISSMLQDIRALRHTEIDYINGFLLRRARAHGIAVP
                     ENTRLFEMVKRKESEYERIGTGLPRPW"
     gene            3140..3730
                     /gene="yajL"
                     /locus_tag="RHX21_001838"
     CDS             3140..3730
                     /gene="yajL"
                     /locus_tag="RHX21_001838"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308505.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein deglycase YajL"
                     /protein_id="HDV1987023.1"
                     /translation="MSASALVCLAPGSEETEAVTTIDLLVRGGIKVTTASVASDGNLA
                     ITCSRGVKLLADAPLVEVADGEYDVIVLPGGIKGAECFRDSTLLVETVKQFHRSGRIV
                     AAICAAPATVLVPHDIFPIGNMTGFPTLKDKIPAEQWQDKRVVWDARVKLLTSQGPGT
                     AIDFGLKIIDLLVGREKAHEVASQLVMAAGIYNYYE"
     gene            complement(3784..5232)
                     /gene="thiI"
                     /locus_tag="RHX21_001839"
     CDS             complement(3784..5232)
                     /gene="thiI"
                     /locus_tag="RHX21_001839"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014168857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HDV1987024.1"
                     /translation="MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVV
                     RHWDNIEVRAKDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALVQYRDQL
                     EGKTFCVRVKRRGKHDFSSIDVERYVGGGLNQHIESARVKLTNPEVTVHLEVEDNRLL
                     LIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEI
                     GVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKIDDGQMGVILKRMMVRAASKVA
                     ERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTE
                     DFARTMPEYCGVISKSPTVKAVKSKIEAEEEKFDFSILDKVVEEANNVDIREIAQQTE
                     QEVVEVETVNGFGPNDVILDIRSIDEQEDKPLKVEGIDVVSLPFYKLSTKFGDLDQNR
                     TWLLWCERGVMSRLQALYLREQGFNNVKVYRP"
     gene            5438..5680
                     /gene="xseB"
                     /locus_tag="RHX21_001840"
     CDS             5438..5680
                     /gene="xseB"
                     /locus_tag="RHX21_001840"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HDV1987025.1"
                     /translation="MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQ
                     LARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE"
     gene            5680..6579
                     /gene="ispA"
                     /locus_tag="RHX21_001841"
     CDS             5680..6579
                     /gene="ispA"
                     /locus_tag="RHX21_001841"
                     /EC_number="2.5.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2E,6E)-farnesyl diphosphate synthase"
                     /protein_id="HDV1987026.1"
                     /translation="MDFPQQLEACVKQANQALSRFIAPLPFQNTPVVETMQYGALLGG
                     KRLRPFLVYATGHMFGVSTNTLDAPAAAVECIHAYSLIHDDLPAMDDDDLRRGLPTCH
                     VKFGEANAILAGDALQTLAFSILSDANMPEVSDRDRISMISELASASGIAGMCGGQAL
                     DLDAEGKHVPLDALERIHRHKTGALIRAAVRLGALSAGDKGRRALPVLDKYAESIGLA
                     FQVQDDILDVVGDTATLGKRQGADQQLGKSTYPALLGLEQARKKARDLIDDARQSLKQ
                     LAEQSLDTSALEALADYIIQRNK"
     gene            6604..8466
                     /gene="dxs"
                     /locus_tag="RHX21_001842"
     CDS             6604..8466
                     /gene="dxs"
                     /locus_tag="RHX21_001842"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HDV1987027.1"
                     /translation="MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVS
                     RSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKG
                     GLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMA
                     FEAMNHAGDIRPDMLVVLNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSG
                     VPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQ
                     FLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAA
                     KDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYKPIVAIY
                     STFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMT
                     PSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLAI
                     LNFGTLMPDAAKVAESLNATLVDMRFVKPLDEALILEMAASHEALVTVEENAIMGGAG
                     SGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLDAAGMEAKIKAWLA"
     gene            8646..9620
                     /gene="yajO"
                     /locus_tag="RHX21_001843"
     CDS             8646..9620
                     /gene="yajO"
                     /locus_tag="RHX21_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414953.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxyxylulose-5-phosphate synthase YajO"
                     /protein_id="HDV1987028.1"
                     /translation="MQYNPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPII
                     KRALEGGINFFDTANSYSDGSSEEIVGRALRDFARREDVVVATKVFHRVGDLPEGLSR
                     AQILRSIDDSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMH
                     ASQFAQALKLQKQHGWAQFISMQDHYNLIYREEEREMLPLCYQEGVAVIPWSPLARGR
                     LTRPWGETTARLVSDEVGRNLYKESDENDAQIAERLTGVSEELGATRAQVALAWLLSK
                     PGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHAVVGFK"
     gene            complement(9674..10192)
                     /gene="pgpA"
                     /locus_tag="RHX21_001844"
     CDS             complement(9674..10192)
                     /gene="pgpA"
                     /locus_tag="RHX21_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HDV1987029.1"
                     /translation="MTILPRHKDVAKSRLKMSNPWHLLAVGFGSGLSPIVPGTMGSLA
                     AIPFWYLMTFLPWQLYSLVVMLGICIGVYLCHQTAKDMGVHDHGSIVWDEFIGMWITL
                     MALPTNDWQWVAAGFVIFRILDMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAGILY
                     FIGHHWPLGILS"
     gene            complement(10170..11147)
                     /gene="thiL"
                     /locus_tag="RHX21_001845"
     CDS             complement(10170..11147)
                     /gene="thiL"
                     /locus_tag="RHX21_001845"
                     /EC_number="2.7.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-phosphate kinase"
                     /protein_id="HDV1987030.1"
                     /translation="MACGEFSLIARYFDRVRSSRLDVELGIGDDCALLNIPEKQTLAI
                     STDTLVAGNHFLHDIDPADLAYKALAVNLSDLAAMGADPAWLTLALTLPDVDEAWLES
                     FSDSLFDLLNYYDMQLIGGDTTRGPLSMTLGIHGFVPMGRALTRSGAKPGDWIYVTGT
                     PGDSAAGLAILQNRLQVADAKDADYLIKRHLRPSPRILQGQALRDLANSAIDLSDGLI
                     SDLGHIVKASDCGARIDLALLPFSDALSRHVEPEQALRWALSGGEDYELCFTVPELNR
                     GALDVALGHLGVPFTCIGQMTADIEGLCFIRDGEPVTFDWKGYDHFATP"
     gene            complement(11225..11644)
                     /gene="nusB"
                     /locus_tag="RHX21_001846"
     CDS             complement(11225..11644)
                     /gene="nusB"
                     /locus_tag="RHX21_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HDV1987031.1"
                     /translation="MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVD
                     VLYFRELLAGVATNTAYLDGLMKPYLSRLLEELGQVEKAVLRIALYELSKRSDVPYKV
                     AINEAIELAKSFGAEDSHKFVNGVLDKAAPVIRPNKK"
     gene            complement(11664..12134)
                     /gene="ribE"
                     /locus_tag="RHX21_001847"
     CDS             complement(11664..12134)
                     /gene="ribE"
                     /locus_tag="RHX21_001847"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HDV1987032.1"
                     /translation="MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQV
                     KDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLA
                     HVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA"
     gene            complement(12223..13326)
                     /gene="ribD"
                     /locus_tag="RHX21_001848"
     CDS             complement(12223..13326)
                     /gene="ribD"
                     /locus_tag="RHX21_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HDV1987033.1"
                     /translation="MQDEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQ
                     RAGEPHAEVHALRMAGEKAKGATAYVTLEPCSHHGRTPPCCDALIAAGVARVVASMQD
                     PNPQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQLKLGASLDGR
                     TAMASGESQWITSPQARRDVQRQRAQSHAILTSSATVLADDPALTVRWSELDEQTQAL
                     YPQQNLRQPVRIVIDSQNRVTPEHRIVQQPGETWFARTQEDSSEWPETVRTLLIPEHK
                     GHLDLVVLMMQLGKQQINSIWVEAGPTLAGALLQAGLVDELIVYIAPKLLGSDARGLC
                     TLPGLEKLADAPQFKFKEIRHVGPDVCLHLVGA"
     gene            complement(13330..13779)
                     /gene="nrdR"
                     /locus_tag="RHX21_001849"
     CDS             complement(13330..13779)
                     /gene="nrdR"
                     /locus_tag="RHX21_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HDV1987034.1"
                     /translation="MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVA
                     ELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGERE
                     VPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED"
     gene            13930..14469
                     /locus_tag="RHX21_001850"
     CDS             13930..14469
                     /locus_tag="RHX21_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414946.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3251 domain-containing protein"
                     /protein_id="HDV1987035.1"
                     /translation="MNTNVFRLLLLGSLFSLSACVQQSEVRQMKHSVSTLNQEMTQLN
                     KETVKITQQNRLNAKSSSGVYLLPGAKTPARLESQIGTLRMSLVNITPDADGTTLTLR
                     IQGESNDPLPAFSGTVEYGQIQGTIDNFQEINVQNQLINAPASVLAPSDVDIPLQLKG
                     ISVDQLGFVRIHDIQPVMQ"
     gene            14768..15652
                     /gene="tsx"
                     /locus_tag="RHX21_001851"
     CDS             14768..15652
                     /gene="tsx"
                     /locus_tag="RHX21_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-specific channel-forming protein Tsx"
                     /protein_id="HDV1987036.1"
                     /translation="MKKTLLAAGAVLALSSSFTVNAAENDKPQYLSDWWHQSVNVVGS
                     YHTRFGPQIRNDTYLEYEAFAKKDWFDFYGYADAPVFFGGNSDAKGIWNHGSPLFMEI
                     EPRFSIDKLTNTDLSFGPFKEWYFANNYIYDMGRNKDGRQSTWYMGLGTDIDTGLPMS
                     LSMNVYAKYQWQNYGAANENEWDGYRFKIKYFVPITDLWGGQLSYIGFTNFDWGSDLG
                     DDSGNAINGIKTRTNNSIASSHILALNYDHWHYSVVARYWHDGGQWNDDAELNFGNGN
                     FNVRSTGWGGYLVVGYNF"
     gene            complement(15829..16176)
                     /locus_tag="RHX21_001852"
     CDS             complement(15829..16176)
                     /locus_tag="RHX21_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH nuclease family protein"
                     /protein_id="HDV1987037.1"
                     /translation="MAIIPKNYARLESGYREKALKIYPWVCGRCSREFVYSNLRELTV
                     HHIDHDHTNNPEDGSNWELLCLYCHDHEHSKYTEADQYGTTVIAGEDAQKDVGEAKYN
                     PFADLKAMMNKKK"
     gene            complement(16305..17276)
                     /gene="secF"
                     /locus_tag="RHX21_001853"
     CDS             complement(16305..17276)
                     /gene="secF"
                     /locus_tag="RHX21_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecF"
                     /protein_id="HDV1987038.1"
                     /translation="MAQEYTVEQLNHGRKVYDFMRWDYWAFGISGLLLIAAIVIMGVR
                     GFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGFEEPMLQNFGSSHDIMVRMPPAE
                     GETGGQVLGSQVLKVINESTNQNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVY
                     VGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVS
                     DRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLT
                     MLIGVSIGTASSIYVASALALKLGMKREHMLQQKVEKEGADQPSILP"
     gene            complement(17287..19134)
                     /gene="secD"
                     /locus_tag="RHX21_001854"
     CDS             complement(17287..19134)
                     /gene="secD"
                     /locus_tag="RHX21_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecD"
                     /protein_id="HDV1987039.1"
                     /translation="MLNRYPLWKYVMLIVVIVIGLLYALPNLFGEDPAVQITGARGVA
                     ASEQTLIQVQKTLQEEKITAKSVALEEGAILARFDSTDTQLRAREALMGVMGDKYVVA
                     LNLAPATPRWLAAIHAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSDLRE
                     KGIPYTTVRKENNYGLSITFRDAKARDEAIAYLSKRHPDLVISSQGSNQLRAVMSDAR
                     LSEAREYAVQQNINILRNRVNQLGVAEPVVQRQGADRIVVELPGIQDTARAKEILGAT
                     ATLEFRLVNTNVDQAAAASGRVPGDSEVKQTREGQPVVLYKRVILTGDHITDSTSSQD
                     EYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEV
                     INIANIQSRLGNSFRITGINNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNI
                     EQGLEACLAGLLVSILFMIIFYKKFGLIATSALIANLILIVGIMSLLPGATLSMPGIA
                     GIVLTLAVAVDANVLINERIKEELSNGRTVQQAIDEGYRGAFSSIFDANITTLIKVII
                     LYAVGTGAIKGFAITTGIGVATSMFTAIVGTRAIVNLLYGGKRVKKLSI"
     gene            complement(19162..19494)
                     /gene="yajC"
                     /locus_tag="RHX21_001855"
     CDS             complement(19162..19494)
                     /gene="yajC"
                     /locus_tag="RHX21_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HDV1987040.1"
                     /translation="MSFFISDAVAATGAPAQGSPMSLILMLVVFGLIFYFMILRPQQK
                     RTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENGYIAIALNDTTEVVIKRDFVAAVL
                     PKGTMKAL"
     gene            complement(19517..20644)
                     /gene="tgt"
                     /locus_tag="RHX21_001856"
     CDS             complement(19517..20644)
                     /gene="tgt"
                     /locus_tag="RHX21_001856"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HDV1987041.1"
                     /translation="MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPE
                     EVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIR
                     KITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSME
                     MSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVG
                     EPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGH
                     LFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHN
                     LRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD"
     gene            complement(20700..21770)
                     /gene="queA"
                     /locus_tag="RHX21_001857"
     CDS             complement(20700..21770)
                     /gene="queA"
                     /locus_tag="RHX21_001857"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HDV1987042.1"
                     /translation="MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFT
                     DLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPK
                     PGAELLLGDDESINATMTARHGALFEVEFNDERSVLDILNSIGHMPLPPYIDRPDEDA
                     DRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVD
                     TIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPF
                     FDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRF
                     FSYGDAMFITYNPQAINERVGE"
     gene            21863..22444
                     /gene="acpH"
                     /locus_tag="RHX21_001858"
     CDS             21863..22444
                     /gene="acpH"
                     /locus_tag="RHX21_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP phosphodiesterase"
                     /protein_id="HDV1987043.1"
                     /translation="MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHM
                     HRRIDVLTDNLPEVREAREWFRSETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFV
                     CYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALR
                     DSWYDLDAHYDALETRFWQFYPRMMAQASHKAL"
     gene            complement(22449..24266)
                     /gene="malZ"
                     /locus_tag="RHX21_001859"
     CDS             complement(22449..24266)
                     /gene="malZ"
                     /locus_tag="RHX21_001859"
                     /EC_number="3.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308480.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin glucosidase"
                     /protein_id="HDV1987044.1"
                     /translation="MMLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDN
                     EEMSVSMHKQRSQQQPGVTAWRAAIDLSSGQPRRRYSFKLLWHDRQRWFTPQGFSRMP
                     PARLEQFAVDVPDIGPQWAADQIFYQIFPDRFARSLPREAEQDHVYYHHAAGQEIILR
                     DWDEPVTAQAGGSTFYGGDLDGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYR
                     HVDPQFGGDGALLRLRHNTQQLGMRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPES
                     PWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSIVRHWLKAPWSMDGW
                     RLDVVHMLGEAGGARNNMQHVAGITEAAKETQPEAYIVGEHFGDARQWLQADVEDAAM
                     NYRGFTFPLWGFLANTDISYDPQQIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDT
                     ARFKTLLGRDIARLPLAVVWLFTWPGVPCIYYGDEVGLDGKNDPFCRKPFPWQVEKQD
                     TALFALYQRMIALRKKSQALRRGGCQVLYAEDNVVVFVRVLNQQRVLVAINRGEACEV
                     VLPASPFLNVAQWQRKEGHGQLTNGILALPAISATVWMN"
     gene            complement(24422..25795)
                     /gene="proY"
                     /locus_tag="RHX21_001860"
     CDS             complement(24422..25795)
                     /gene="proY"
                     /locus_tag="RHX21_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline-specific permease ProY"
                     /protein_id="HDV1987045.1"
                     /translation="MESKNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSV
                     LLAYIIGGIAAYIIMRALGEMSVHNPAASSFSRYAQENLGPLAGYITGWTYCFEILIV
                     AIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATI
                     IIMIVAGFGIIIWGIGNGGQPTGIHNLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEII
                     GITAGEAKDPEKSIPRAINSVPMRILVFYVGTLFVIMSIYPWNQVGTAGSPFVLTFQH
                     MGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAPKIFSKTSRRGIPWVT
                     VLVMTTALLFAVYLNYIMPENVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVK
                     ALKFKVPGGVATTIGGLIFLLFIIGLIGYHPDTRISLYVGFAWIVVLLIGWMFKRRHD
                     RQLAENQ"
     gene            complement(25871..27190)
                     /gene="brnQ"
                     /locus_tag="RHX21_001861"
     CDS             complement(25871..27190)
                     /gene="brnQ"
                     /locus_tag="RHX21_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transporter carrier
                     protein BrnQ"
                     /protein_id="HDV1987046.1"
                     /translation="MTHQLRSRDIIALGFMTFALFVGAGNIIFPPMVGLQAGEHVWTA
                     AFGFLITAVGLPVLTVVALAKVGGGVDSLSTPIGKVAGVLLATVCYLAVGPLFATPRT
                     ATVSFEVGIAPLTGDSALPLFIYSLVYFAIVILVSLYPGKLLDTVGNFLAPLKIIALV
                     ILSVAAIVWPAGSISTATEAYQNAAFSNGFVNGYLTMDTLGAMVFGIVIVNAARSRGV
                     TEARLLTRYTVWAGLMAGVGLTLLYLALFRLGSDSASLVDQSANGAAILHAYVQHTFG
                     GGGSFLLAALIFIACLVTAVGLTCACAEFFAQYVPLSYRTLVFILGGFSMVVSNLGLS
                     QLIQISVPVLTAIYPPCIALVVLSFTRSWWHNSSRVIAPPMFISLLFGILDGIKASAF
                     SDILPSWAQRLPLAEQGLAWLMPTVVMVVLAIIWDRAAGRQVTSSAH"
     gene            complement(27597..28892)
                     /gene="phoR"
                     /locus_tag="RHX21_001862"
     CDS             complement(27597..28892)
                     /gene="phoR"
                     /locus_tag="RHX21_001862"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate regulon sensor histidine kinase PhoR"
                     /protein_id="HDV1987047.1"
                     /translation="MLERLSWKRLVLELLLCCFPAFILGAFFGYLPWFLLASVTGLLI
                     WHFWNLLRLSWWLWVDRSMTPPPGRGSWEPLLYGLHQMQLRNKKRRRELGNLIKRFRS
                     GAESLPDAVVLTTEEGGIFWCNGLAQQILGLRWPEDNGQNILNLLRYPEFTQYLKTRD
                     FSRPLNLVLNTGRHLEIRVMPYTHKQLLMVARDVTQMHQLEGARRNFFANVSHELRTP
                     LTVLQGYLEMMDEQPLEGAVREKALHTMREQTQRMEGLVKQLLTLSKIEAAPTHLLNE
                     KVDVPMMLRVVEREAQTLSQKKQTFTFEIDNGLKVSGNEDQLRSAISNLVYNAVNHTP
                     EGTHITVRWQRVPHGAEFSVEDNGPGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLA
                     IVKHAVNHHESRLNIESTVGKGTRFSFVIPERLIAKNSD"
     gene            complement(28950..29639)
                     /gene="phoB"
                     /locus_tag="RHX21_001863"
     CDS             complement(28950..29639)
                     /gene="phoB"
                     /locus_tag="RHX21_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate response regulator transcription
                     factor PhoB"
                     /protein_id="HDV1987048.1"
                     /translation="MARRILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNE
                     PWPDLILLDWMLPGGSGIQFIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDY
                     ITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPTSHRVMAGEEPLEMGPTEF
                     KLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALEPGGHDRMVQTV
                     RGTGYRFSTRF"
     gene            29829..31031
                     /gene="sbcD"
                     /locus_tag="RHX21_001864"
     CDS             29829..31031
                     /gene="sbcD"
                     /locus_tag="RHX21_001864"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease subunit SbcD"
                     /protein_id="HDV1987049.1"
                     /translation="MRILHTSDWHLGQNFYSKSREAEHQAFLDWLLETAQTHQVDAII
                     VAGDVFDTGSPPSYARTLYNRFVVNLQQTGCHLVVLAGNHDSVATLNESRDIMAFLNT
                     TVVASAGHAPQILPRRDGTPGAVLCPIPFLRPRDIITSQAGLNGIEKQQHLLAAITDY
                     YQQHYADACKLRGDQPLPIIATGHLTTVGASKSDAVRDIYIGTLDAFPAQNFPPADYI
                     ALGHIHRAQIIGGMEHVRYCGSPIPLSFDECGKSKYVHLVTFSNGKLESVENLNVPVT
                     QPMAVLKGDLASITAQLEQWRDVSQEPPVWLDIEITTDEYLHDIQRKIQALTESLPVE
                     VLLVRRSREQRERVLASQQRETLSELSVEEVFNRRLALEELDESQQQRLQHLFTTTLH
                     TLAGEHEA"
     gene            31028..34171
                     /gene="sbcC"
                     /locus_tag="RHX21_001865"
     CDS             31028..34171
                     /gene="sbcC"
                     /locus_tag="RHX21_001865"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308474.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease subunit SbcC"
                     /protein_id="HDV1987050.1"
                     /translation="MKILSLRLKNLNSLKGEWKIDFSREPFASNGLFAITGPTGAGKT
                     TLLDAICLALYHETPRLSNVSQSQNDLMTRDTAECLAEVEFEVKGEAYRAFWSQNRAR
                     NQPDGNLQVPRVELARCADGKILADKVKDKLELTATLTGLDYGRFTRSMLLSQGQFAA
                     FLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVALLTPEQV
                     QSLTASLQVLTDEEKQLLTAQQQEQQSLNWLTRLDELQQEASRRQQALQQALAEEEKA
                     QPQLAALSLAQPARNLRPHWERIAEHSAALAHTRQQIEEVNTRLQSTMALRASIRHHA
                     AKQSAELQQQQQSLNTWLQEHDRFRQWNNELAGWRAQFSQQTSDREHLRQWQQQLTHA
                     EQKLNALAAITLTLTADEVATALAQHAEQRPLRQHLVALHGQIVPQQKRLAQLQVAIQ
                     NVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQEARIKTLEAQRAQLQAGQPCPL
                     CGSTSHPAVEAYQALEPGVNQSRLLALENEVKKLGEEGAALRGQLDALTKQLQRDENE
                     AQSLRQDEQALTQQWQAVTASLNITLQPQDDIQPWLDAQDEHERQLRLLSQRHELQGQ
                     IAAHNQQIIQYQQQIEQRQQQLLTALAGYALTLPQEDEEESWLATRQQEAQSWQQRQN
                     ELTALQNRIQQLTPILETLPQSDDLPHSEETVALDNWRQVHEQCLALHSQQQTLQQQD
                     VLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQT
                     LVTQTAETLAQHQQHRPDGLALTVTVEQIQQELAQTHQKLRENTTSQGEIRQQLKQDA
                     DNRQQQQTLMQQIAQMTQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVHLANQQL
                     TRLHGRYLLQRKASEALEVEVVDTWQADAVRDTRTLSGGESFLVSLALALALSDLVSH
                     KTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKERIPVQIKVK
                     KINGLGYSKLESTFAVK"
     gene            34297..35481
                     /gene="araJ"
                     /locus_tag="RHX21_001866"
     CDS             34297..35481
                     /gene="araJ"
                     /locus_tag="RHX21_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414930.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter AraJ"
                     /protein_id="HDV1987051.1"
                     /translation="MKKVILSLALGTFGLGMAEFGIMGVLTELAHNVGISIPAAGHMI
                     SYYALGVVVGAPIIALFSSRYSLKHILLFLVALCVIGNAMFTLSSSYLMLAIGRLVSG
                     FPHGAFFGVGAIVLSKIIKPGKVTAAVAGMVSGMTVANLLGIPLGTYLSQEFSWRYTF
                     LLIAVFNIAVMASVYFWVPDIRDEAKGKLREQFHFLRSPAPWLIFAATMFGNAGVFAW
                     FSYVKPYMMFISGFSETAMTFIMMLVGLGMVLGNMLSGRISGRYSPLRIAAVTDFIIV
                     LALLMLFFCGGMKTTSLIFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAFN
                     LGSAVGAYCGGMMLTLGLAYNYVALPAALLSFAAMSSLLLYGRYKRQQAADSPVLAKP
                     LG"
     gene            complement(35624..36532)
                     /gene="mak"
                     /locus_tag="RHX21_001867"
     CDS             complement(35624..36532)
                     /gene="mak"
                     /locus_tag="RHX21_001867"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414928.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase"
                     /protein_id="HDV1987052.1"
                     /translation="MRIGIDLGGTKTEVIALGDAGEQLYRHRLPTPRDDYRQTIETIA
                     TLVDMAEQATGQRGTVGMGIPGSISPYTGVVKNANSTWLNGQPFDKDLSARLQREVRL
                     ANDANCLAVSEAVDGAAAGAQTVFAVIIGTGCGAGVAFNGRAHIGGNGTAGEWGHNPL
                     PWMDEDELRYREEVPCYCGKQGCIETFISGTGFATDYRRLSGHALKGSEIISLVEESD
                     PVAELALRRYELRLAKSLAHVVNILDPDVIVLGGGMSNVDRLYQTVGQLIKQFVFGGE
                     CETPVRKAKHGDSSGVRGAAWLWPQE"
     gene            36657..37568
                     /gene="rdgC"
                     /locus_tag="RHX21_001868"
     CDS             36657..37568
                     /gene="rdgC"
                     /locus_tag="RHX21_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-associated protein RdgC"
                     /protein_id="HDV1987053.1"
                     /translation="MLWFKNLMVYRLSREISLRAEEMEKQLASMAFTPCGSQDMAKMG
                     WVPPMGSHSDALTHVANGQIVICARKEEKILPSPVIKQALEAKIAKLEAEQARKLKKT
                     EKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGS
                     LPVVPLSMENPIELTLTEWVRSGSAAQGFQLLDEAELKSLLEDGGVIRAKKQDLTSEE
                     ITNHIEAGKVVTKLALDWQQRIQFVMCDDGSLKRLKFCDELRDQNEDIDREDFAQRFD
                     ADFILMTGELAALIQNLIEGLGGEAQR"
     gene            complement(37646..38065)
                     /locus_tag="RHX21_001869"
     CDS             complement(37646..38065)
                     /locus_tag="RHX21_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987054.1"
                     /translation="MYELLTPTINLQIHCTRYPMRSQNGGSTDLPRYWITLDKNVIWD
                     YPKDFIAGNGGVRNFHGETCWYPYLTDICSISDLLREYIDTPKAELLTKQFTSDKWGL
                     VNILRAADRRIGMRRLDQLRRKTHNIAALKIIARRSE"
     gene            complement(38269..38553)
                     /gene="ppnP"
                     /locus_tag="RHX21_001870"
     CDS             complement(38269..38553)
                     /gene="ppnP"
                     /locus_tag="RHX21_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HDV1987055.1"
                     /translation="MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEE
                     MTVISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL"
     gene            complement(38625..39302)
                     /locus_tag="RHX21_001871"
     CDS             complement(38625..39302)
                     /locus_tag="RHX21_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AroM family protein"
                     /protein_id="HDV1987056.1"
                     /translation="MSASLAILTIGIVPMQEVLPLLTEYIDEDNISHHSLLGKLSREE
                     VMAEYAPEAGEDTILTLLNDNQLAHVSRRKVERDLQGVVEVLDNRGYDVIILMSTANI
                     SSMTARNTIFLEPSRILPPLVSSIVEDHQVGVIVPVEEMLPVQAQKWQILQKSPVFSL
                     GNPIHDSEQKIIDAGKELLAKGADVIMLDCLGFHQRHRDLLQKQLDVPVLLSNVLIAR
                     LAAELLV"
     gene            complement(39560..39751)
                     /gene="yaiA"
                     /locus_tag="RHX21_001872"
     CDS             complement(39560..39751)
                     /gene="yaiA"
                     /locus_tag="RHX21_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YaiA"
                     /protein_id="HDV1987057.1"
                     /translation="MPTKPPYPREAYIVTIEKGKPGQTVTWYQLRADHPKPDSLISEH
                     PTAQEAMDAKKRYEDPDKE"
     gene            complement(39801..40325)
                     /gene="aroL"
                     /locus_tag="RHX21_001873"
     CDS             complement(39801..40325)
                     /gene="aroL"
                     /locus_tag="RHX21_001873"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase AroL"
                     /protein_id="HDV1987058.1"
                     /translation="MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMT
                     VAEIVEREEWAGFRARETAALEAVTAPSTVIATGGGIILTEFNRHFMQNNGIVVYLCA
                     PVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQV
                     ISEIRSALAQTINC"
BASE COUNT        10034 a        10816 c        10227 g         9365 t
ORIGIN      
        1 aaaacatacc tgacacacaa attactctcc tctgtaatat tttctcatta acactctgtt
       61 tacccaacat gcgctccgca ctacactatg tgggcatttt tttaaggggt ggtaatgaac
      121 gattataaaa tgacgccagg tgagaggcgc gtgacctggg gtttagggac cgtattctcg
      181 ttgcgcatgc tgggcatgtt tatggttctg ccggttctga ccacgtacgg catggctctg
      241 caaggtgcca gcgaagcatt aatcggtatt gccattggta tttatggtct gactcaggcc
      301 gtttttcaga ttccgtttgg cctgctttcc gaccgcattg gtcgcaaacc attaattgtc
      361 ggtgggctgg cggtgtttgc cgccggtagc gttatcgctg cgctttccga ctccatctgg
      421 ggaattattc tgggccgggc gctacaaggc tctggagcaa ttgccgccgc cgttatggcg
      481 ctgctttccg atctcacgcg cgaacaaaac cgcaccaaag cgatggcgtt tatcggcgtg
      541 agctttggca ttacctttgc cattgcgatg gtgcttggcc cgatcatcac tcacaaactt
      601 gggctgcacg cgctgttctg gatgatcgct attctggcaa caaccggcat tgcgttgacc
      661 atttgggttg tgcccaacag tagcactcac gtacttaatc gtgagtccgg aatggtgaaa
      721 ggcagtttca gtaaagtgct ggcggaaccg cggctgctaa aactcaactt tggcattatg
      781 tgtctgcaca tgcttctgat gtctacgttt gttgccctgc ccggacagct agctgatgcg
      841 gggttcccgg cggctgaaca ctggaaggtc tatctggcga cgatgttaat cgcctttggc
      901 tcggtcgtgc ctttcattat ctacgctgaa gttaagcgca aaatgaagca agtctttgtc
      961 ttctgcgtcg ggttgatcgt ggttgcggaa attgtgttgt ggaacgcaca aacgcagttc
     1021 tggcaactgg tggtcggcgt gcagcttttc tttgtggcgt ttaatttgat ggaagccctt
     1081 ctgccctcac ttatcagtaa agagtcgcca gcaggttaca aaggtacggc gatgggtgtc
     1141 tactccacca gccagtttct tggcgtggcg attggcggtt cgctgggcgg ctggattgac
     1201 ggcatgtttg acggtcaggg ggtatttctc gctggcgcaa tgctggccgc agtgtggctg
     1261 gcagtcgcca gtaccatgaa agaaccgccg tatgtcagca gtttgcgcat tgaaatcccg
     1321 gcggacattg ccgcaaacga agcgttaaaa gtgcgtttgc tggaaactga aggcgtcaaa
     1381 gaagtgttga ttgcagaaga agagcattca gcttatgtga aaatcgacag caaagtgaca
     1441 aatcgctttg aggttgaaca ggcaattcgt caggcataaa aaacgcggcg aattgcctgc
     1501 tgcgctacgc ttaccaggcc tacaaagttc ttgagttaca aaccgttgta ggccgaatca
     1561 ggcgttcatg ccgcatctga catgaacaaa acgcacattg tcgcgattaa tcgcggaagt
     1621 ttttgaactg gaacggctgg ccgagatcgc caccacgtac catcgccatg acagcctgca
     1681 aatcatcacg agatttgcca gtcacacgga tctcatcgcc ctgaatttgc gcctgcactt
     1741 tcagtttgct gtctttaatc atcttgacga ttttcttctg ggtcgcgctc tcaatgccct
     1801 gtttcagttt cgcttccaca aaccaggttt taccgctatg aacgatattt tccggtacat
     1861 ccagtgaact gccttcaatg ccgcgcttca gcagcttggc acgcagaata tccagcaact
     1921 gattgacctg gaagtcggac tcgctcaaca ctttgatggt tttgctggcg tcgttcagct
     1981 caaatgaggc ttcaacgtta cggaagtcaa aacgggactc cacttcgcga ctcgcgttat
     2041 cgaccgcgtt acgtgcttcc tgaagatcaa cttcagagac aatatcgaaa gatggcatct
     2101 tttcctctcc cttcattttt gatgcgaagc ataatacctg caaagttaaa taaccaacag
     2161 tcctgcacca ggacgtatcc cttaattgtg catagtcgca acagcatgca caattaaggg
     2221 atagccttat tgaacacccg gagtggttgc gggtgaggag gaacaatgaa aattaccgta
     2281 ttgggatgcg gtgccttagg gcaattatgg cttacagcac tttgtaaaca gggtcatgaa
     2341 gttcagggct ggctgcgcgt accgcaacct tattgtagtg tgaatctggt tgagacagat
     2401 ggtgcgatat ttaacgaatc gctgaccgcc aacgatcccg attttctcgc caccagcgat
     2461 ctgctcctgg tgacgctgaa agcatggcag gtttccgatg ccgtcaaaag cctcgcatcc
     2521 acactgcctg tagctacgcc aatactgtta attcacaacg gcatgggcac catcgaagaa
     2581 ttgcaaaaca ttcagcagcc attactgatg ggcaccacca cccatgccgc ccgccgcgac
     2641 ggcaatgtca ttattcatgt ggcaaacgga atcacgcata tcggtccggc acggcaacag
     2701 gatggcgatt acagttatct ggcggatatt ttgcaaaccg tgttgcctga cgttgcctgg
     2761 cataacaata ttcgcgccga gctgtggcgc aagctggccg tcaactgtgt gattaatcca
     2821 ctgaccgcca tctggaattg cccgaatggt gaattacgtc atcatccgca agaaattatg
     2881 cagatatgcg aagaagtcgc ggcagtgatc gagcgcgaag ggcatcatac ttcagcagaa
     2941 gatttgcgtg attacgtgat gcaggtgatt gatgccacag cggaaaatat ctcgtcgatg
     3001 ttgcaggata tccgcgcgct gcgccacacc gaaatcgact atatcaatgg ttttctctta
     3061 cgccgcgccc gcgcgcatgg gattgccgta ccggaaaaca cccgcctgtt tgaaatggta
     3121 aaaagaaagg agagtgaata tgagcgcatc ggcactggtt tgcctcgccc ctggtagtga
     3181 agagactgaa gccgtcacca ctatcgatct gctggttcgc ggcggtatca aagtcaccac
     3241 tgccagcgtc gccagcgatg gcaacctggc cattacctgc tcgcgcggcg tgaagctgct
     3301 ggcggatgcg ccgctggtcg aggtggctga tggcgaatat gacgtgatcg tactgcctgg
     3361 tggcattaaa ggcgcagagt gttttcgcga tagtaccctg ctggttgaaa ccgttaaaca
     3421 gttccaccgt tccgggcgta tcgtcgcggc tatttgcgcc gcgccagcca ccgtgctggt
     3481 gccgcacgat atcttcccga ttggtaatat gaccggcttc ccgacgctga aagacaaaat
     3541 tcccgctgaa caatggcagg acaagcgcgt cgtctgggat gcacgggtaa aattgctgac
     3601 cagccagggg ccggggacag ctatcgactt tggtctgaaa attatcgacc tgctggttgg
     3661 gcgcgagaaa gcccatgaag tggcatcaca actggtgatg gcggcaggga tttataatta
     3721 ttacgagtag tgtcggatgc ggtaagcgtc gcatctgacc agatgcgacg ttacaaccac
     3781 aaattacggg cgatatacct tcacattgtt aaagccctgc tcgcgcagat agagcgcctg
     3841 cagacggctc atcaccccgc gctcacacca cagtagccag gttctgttct ggtcgagatc
     3901 gccaaacttg gtgctcagtt tatagaacgg cagagaaact acatcaatcc cttcgacttt
     3961 cagtggctta tcttcctgtt catcgataga acggatatcg aggatcacgt cgttcgggcc
     4021 gaagccattg acggtttcca cttccaccac ttcctgctcg gtctgctggg cgatttcgcg
     4081 gatatcaacg ttattcgctt cttcaaccac tttatcgaga atgctgaagt cgaatttctc
     4141 ttcttccgct tcaatcttcg acttaaccgc tttcaccgtc gggcttttgg agataacacc
     4201 gcaatattcc ggcatcgtgc gagcaaagtc ttcggtgcca atctggcgag ccaggttgat
     4261 gatgtgctct ttgtcgtaag aaatcagcgg acgcaggatc agcgtatcgg agacgttatc
     4321 aatcaggcgc aggttggtca gcgtctgact ggacacctgg ccgagcgctt cgccggtgac
     4381 cagcgcctgt acgccgtaac gttcagccac tttagacgcg gcacgcacca tcatacgttt
     4441 gaggataacg cccatctgac cgtcgtcgat tttctcgaga atttccccga cgaccggttc
     4501 gaaattaata gcgacaaaac gcacgcggtg ggagctgcca aaacggttcc acagataatg
     4561 cgccacctga cgcacgccaa tttcatgcgc cgcgccgcca aggttaaaga aacagtaatg
     4621 cacgcggcag ccgcgacgca tcaacatata actggaaaca ccggagtcga aaccaccgga
     4681 aatgagcgac agcacatctt cctgggtgcc gatcgggaaa ccgccaatac cttcgtagcg
     4741 gcctttaatc agcaggagac gattgtcttc cacttccaga tggacagtca cttccggatt
     4801 ggtcagcttc acgcgcgcgg actcaatatg ctgatttaaa ccgccgccga cgtaacgttc
     4861 cacatcaatc gagctaaaat catgtttgcc acggcgcttc acgcgtacgc agaaggtttt
     4921 gccttccagc tgatcgcgat actgaaccaa cgctttctca aaaatatcgt gcatgtcggt
     4981 aaacggcacg tcttcgactt cgagaatatg gtggataccc ggaatacggg tcagggcgtc
     5041 gcgaatagcc agacgctggt tttcatcttt tgcgcgaact tcgatgttat cccagtggcg
     5101 gacgacagcg agcgtctcat catagtgctt taaaacgtta cgaatgttcc cggtaaggat
     5161 ttttataaag cgcaagcgca cagattggct tttgatggtg atttccggga acaatttaat
     5221 gataaacttc atggcggcaa tggttcgttg gcaagcctta agcgacttgt atagggaaaa
     5281 atacagcagc ccacacctgc ggctgcatcc aggcgcggaa gtataccact aacatcgctt
     5341 tgctgcgcac atcaccttac cattgcgcgt tatttgctat ttgccctgag tccgttacca
     5401 tgacggggcg aaaaatattg agagtcagac attcattatg ccgaagaaaa atgaggctcc
     5461 cgccagcttt gaaaaggcgc tgagcgagct ggaacagatt gtaacccgtc tggaaagtgg
     5521 cgacctgccg ctggaagagg cgctgaacga gttcgaacgc ggcgtgcagc tggcacgtca
     5581 ggggcaggcc aaattacaac aagccgaaca gcgcgtacaa attctgctgt ctgacaatga
     5641 agacgcctct ctaacccctt ttacaccgga caatgagtaa tggactttcc gcagcaactc
     5701 gaagcctgcg ttaagcaggc caaccaggcg ctgagccgtt ttatcgcccc actgcccttt
     5761 cagaacactc ccgtggtcga aaccatgcag tatggcgcat tattaggtgg taagcgtctg
     5821 cgacccttcc tggtttatgc caccggtcat atgtttggcg ttagcacaaa cacgctggac
     5881 gcacccgctg ccgccgtaga gtgtatccac gcttactcat taattcatga tgatttaccg
     5941 gcgatggatg atgacgatct gcgtcgcggt ttgccgacct gccatgtgaa gtttggcgaa
     6001 gcaaacgcga ttctcgctgg cgacgcttta caaacgctgg cgttctcgat tctaagcgat
     6061 gccaatatgc cggaagtgtc ggatcgcgac agaatttcga tgatttctga actggcgagc
     6121 gccagcggta ttgccggaat gtgcggtggt caggcattag atttagacgc ggaaggcaaa
     6181 cacgtacctc tggacgcgct tgagcgtatt catcgtcata aaaccggcgc attgattcgc
     6241 gccgccgttc gccttggtgc attaagcgcc ggagataaag ggcgtcgtgc tctgccagta
     6301 ctcgacaagt acgcagagag catcggcctt gccttccagg ttcaggatga catcctggat
     6361 gtggtaggag atactgcaac gttgggaaaa cgccagggtg ccgaccagca acttggtaaa
     6421 agtacctacc ctgcacttct gggtcttgag caagcccgga agaaagcccg ggatctgatc
     6481 gacgatgccc gccagtcgct gaaacaactg gctgaacaat cactcgatac ctcggcactg
     6541 gaagcgctag cggactacat catccagcgt aataaataaa caataagtat taataggccc
     6601 ctgatgagtt ttgatattgc caaatacccg accctggcac tggtcgactc cacccaggag
     6661 ttacgactgt tgccgaaaga gagtttaccg aaactctgcg acgaactgcg ccgctattta
     6721 ctcgacagcg tgagccgttc cagcgggcac ttcgcctccg ggctgggcac ggtcgaactg
     6781 accgtggcgc tgcactatgt ctacaacacc ccgtttgacc aattgatttg ggatgtgggg
     6841 catcaggctt atccgcataa aattttgacc ggacgccgcg acaaaatcgg caccatccgt
     6901 cagaaaggcg gcctgcaccc gttcccgtgg cgcggcgaaa gcgaatatga cgtattaagc
     6961 gtcgggcatt catcaacctc catcagtgcc ggaattggta ttgcggttgc tgccgagaaa
     7021 gaaggcaaaa atcgccgcac cgtctgtgtc attggcgatg gcgcgattac cgctggcatg
     7081 gcgtttgaag cgatgaatca cgcgggcgat atccgtcctg atatgctggt ggtcctcaac
     7141 gacaatgaaa tgtcgatttc cgaaaatgtc ggcgcgctca ataaccatct ggcacagctg
     7201 ctttccggta agctttactc ttcgctgcgc gaaggcggga aaaaagtttt ctctggcgtt
     7261 ccgccaatta aagagctgct caaacgtacc gaagaacata ttaaaggcat ggtagtgcct
     7321 ggcacgttgt ttgaagagct gggctttaac tacatcggcc cggttgacgg tcacgatgtg
     7381 ctggggctta tcaccacgct gaagaacatg cgcgacctga aaggcccgca gttcctgcat
     7441 atcatgacca aaaaaggtcg tggttatgaa ccggcagaaa aagaccccat cactttccac
     7501 gccgtgccta aatttgatcc ctccagcggt tgtttgccga aaagtagcgg cggtttgccg
     7561 agctattcaa aaatctttgg cgactggttg tgcgaaacgg cagcgaaaga caacaagctg
     7621 atggcgatta ctccggcgat gcgtgaaggt tccggcatgg tcgagttttc acgtaaattc
     7681 ccggatcgtt acttcgacgt ggcaatcgcc gagcaacacg cggtgacctt tgccgccggt
     7741 ctggcgattg gtgggtacaa acccattgtc gcgatttact ccactttcct gcaacgcgcc
     7801 tatgatcagg tgctgcatga cgtggcgatt caaaagctcc cggtcctgtt cgccatcgac
     7861 cgcgcgggca ttgttggtgc tgacggtcaa acccatcagg gcgcttttga cctctcttac
     7921 ctgcgctgta taccggaaat ggtcattatg accccgagcg atgaaaacga atgtcgccag
     7981 atgctctata ccggctatca ctataacgac ggcccgtccg cggtgcgcta cccgcgcggt
     8041 aacgcggttg gcgtggaact gacgccgctg gaaaaactgc caattggcaa aggcattgtg
     8101 aagcgtcgtg gcgagaaact ggcgatcctt aactttggta cgctgatgcc agacgcggcg
     8161 aaagtcgctg aatcgctgaa cgctacgctg gtcgatatgc gttttgtgaa accgcttgat
     8221 gaagcgttaa ttctggaaat ggccgccagc catgaagcgc tggtcaccgt agaagaaaac
     8281 gccattatgg gcggcgcagg cagcggcgtg aacgaagtgc taatggccca tcgtaaacca
     8341 gtacccgtgc tgaacattgg cctgcctgac ttctttattc cacaaggaac tcaggaagaa
     8401 atgcgcgccg aactcggcct cgatgccgcc ggtatggaag ccaaaatcaa ggcctggctg
     8461 gcataatccc tactccactc ctgctatgct taagaaatta ttcatagact ctaaataatt
     8521 cgagttgcag gaaggcggca aacgagtgaa gccccaggag cttacataag taagtgactg
     8581 gggtgaacga atgcagccgc agcacatgca acttgaagta tgacgagtat agcgggagtg
     8641 gcagcatgca atacaacccc ttaggaaaaa ccgaccttcg cgtttcccga ctttgcctcg
     8701 gctgtatgac ctttggcgag ccagatcgcg gtaatcacgc atggacactg ccggaagaaa
     8761 gcagccgtcc cataattaaa cgtgcactgg aaggcggcat aaatttcttt gataccgcca
     8821 atagctattc cgatggcagc agcgaagaga tcgttggtcg cgcactgcgg gatttcgccc
     8881 gtcgtgaaga cgtggtcgtt gcgacgaaag tgttccatcg cgttggtgat ttaccggaag
     8941 gattatcccg tgcacaaatt ttgcgctcta tcgacgacag cctgcgccgt ctcggcatgg
     9001 attatgtcga tatcctgcaa attcatcgct gggattacaa cacgccgatc gaagagacgc
     9061 tggaagccct gaacgacgtg gtaaaagccg ggaaagcgcg ttatatcggc gcgtcatcca
     9121 tgcacgcttc gcagtttgct caggccctga agctacaaaa acagcacggc tgggcgcagt
     9181 ttatcagtat gcaggatcac tacaatctga tttatcgcga agaagagcgt gagatgctgc
     9241 ctctgtgtta tcaggagggc gtggcggtga ttccgtggag cccgctggcg cgggggcgac
     9301 tgacgcgtcc gtggggagaa actaccgcac gactggtgtc tgatgaggtg gggagaaatc
     9361 tctataaaga aagcgatgaa aatgacgcgc agatcgcaga gcggttaacg ggcgtcagtg
     9421 aagaactcgg tgcaacacga gcacaagttg cgctggcctg gttgttgagt aaaccgggca
     9481 ttgccgcacc gattatcggt acatcgcggg aagaacagct tgatgagctg ctgaacgcgg
     9541 tggatatcac tttgaagcca gaacagattg ccgaactgga aacgccgtat aaaccgcatg
     9601 cggtcgtagg atttaaataa gagtccaggc ctgatgagac gcaacaagcg tcacatcagg
     9661 cactggtgca caactacgac agaataccca gcggccagtg atgaccgata aagtacagga
     9721 tacctgcgga gatcaccccg gcgacaatat catcgatcat gatccccatg ccgccatgta
     9781 cattgcgatc aaaccagcgg atcggccacg gcttccacat atccagaata cggaaaatca
     9841 caaacccggc ggcaacccac tgccagtcat tggtcggcag cgccatgagc gtgatccaca
     9901 taccaataaa ttcgtcccag acaatgctgc cgtgatcgtg cacgcccata tctttcgccg
     9961 tttgatgaca aagatagacg ccgatacaga tccccaacat caccaccagc gagtagagct
    10021 gccagggtaa aaaggtcatc agataccaga acggaatcgc tgccagcgat cccatcgtgc
    10081 caggaacgat tgggcttaat ccacttccga atccgacagc aagcagatgc cacggattac
    10141 tcatcttcag gcgacttttc gcgacatctt tatggcgtgg caaaatggtc atatcctttc
    10201 cagtcaaacg tgacaggttc gccgtcacga ataaaacaaa gcccttcgat atcggcggtc
    10261 atttgcccga tacaggtaaa cggtacgccc aggtgtccga gagccacatc cagcgcgcca
    10321 cggttcagtt ccggcacagt gaaacacaac tcgtaatctt caccgccaga gagcgcccag
    10381 cgcagcgcct gttccggttc aacatggcga gaaagcgcat cagaaaacgg cagcaatgcc
    10441 aggtcaatac gtgcgccgca gtcgctggct ttcacgatat gcccgagatc ggaaatcaga
    10501 ccgtcagaga gatcgatagc tgaatttgcc agatcgcgca gtgcctgtcc ctgtaaaata
    10561 cgcggcgatg gacggagatg acgtttgatc aagtagtccg catctttagc atcggcaacc
    10621 tgcaaacggt tttgcaaaat cgccagcccg gcggcgctat cgcccggtgt accggtcaca
    10681 tagatccagt cacccggttt cgctccagag cgcgttaagg ctcgtcccat cggaacaaag
    10741 ccgtggatac ccaacgtcat tgataatggc ccacgcgtgg tatcgccgcc aatgagttgc
    10801 atatcgtaat aattgagaag atcaaacaaa ctgtcgctga aggactcaag ccacgcttcg
    10861 tctacgtccg gtaaggttaa tgccagcgtc agccaggccg gatcggcccc catcgctgcc
    10921 agatcgctta ggttcaccgc cagtgcttta tacgccagat cagcaggatc gatatcatgg
    10981 aggaagtggt tgcccgccac cagcgtatca gtgctgatcg ccagggtctg tttctcgggg
    11041 atattgagaa gagcgcaatc gtcgccgatg cccagttcga catcaagacg agaacttctt
    11101 acacggtcaa aataacgggc aatcagggag aactcgccac atgccatacg ttatgcctca
    11161 gcaggtaaaa aagaaaaggc cggcgatcgc ggaacggtct tccgtgaatc taccggcctg
    11221 gatatcactt tttgttaggg cgaatcacag gtgctgcttt atcgagtacg ccgttgacga
    11281 acttatggct gtcttctgcg ccgaacgatt tcgccagttc gatcgcttcg ttaatggcca
    11341 ctttgtatgg cacatcgcta cgtttagaca gctcgtacag cgcaatgcgc agtactgctt
    11401 tttctacctg tcccagttct tccagcaggc gggacaggta tggcttcatc agtccgtcga
    11461 ggtatgcggt gttagtcgcc accccggcca gcagctcacg gaagtacagg acgtcaacgt
    11521 cttttacatc ctgttcagcc aggaactggt attcaacatc agcgatgtcg ttctgggaca
    11581 actgccagga gtagagcgcc tggacggcac actcacgagc gcggcgacga gcagcaggtt
    11641 tcacggattt ccccttacta atttcaggcc ttgatggctt tcaatacatt aatcatttca
    11701 agcgcggtca gtgcagcttc tgcacctttg ttgccagctt tggtgccagc acgttcgatc
    11761 gcttgttcaa tgctttcagt ggtcagaacc ccaaaagcaa ccggaatttc gctgtcctgg
    11821 gcaacatgcg ccaggccgtt gcttgcacca ccagcgacat attcaaagtg ggcagtgcca
    11881 ccacgaataa ccgtacccag cgcaatcacc gcgtcgtatt taccggtttt agccagtgca
    11941 cccgccgcca gcggcagctc ataggcacca ggcacccaaa caacggtaat gttttcatct
    12001 tttacctgac cgatacgttt cagtgcgtca attgcacctt ccagcaggct gtcattgata
    12061 aagttgttga aacgcgcgat ggtgatggcg acgcgagcgt ccggggtagc aacgttagct
    12121 tcaataatgt tcattttctt ccttcgggtt cgagtatggc cccgcagggg ggcggatttt
    12181 agcataatat ttcgtgcgct gcttcccttt cgagccggga gatcatgcac ccactaaatg
    12241 caggcaaaca tccgggccta catgacgtat ctctttgaat ttaaattggg gggcgtcggc
    12301 taatttctca agccctggca gcgtgcataa tccgcgggcg tcgctgccta atagtttagg
    12361 tgcgatatag acaatcagct catcgactaa acccgcctgc agcaatgcgc cagcgagcgt
    12421 tggccccgct tccacccaga tgctgttaat ttgctgttta cccagttgca tcatcagtac
    12481 aaccagatcc agatgacctt tatgctctgg aatcagcaag gtacgcaccg tttccggcca
    12541 ctcactagaa tcttcctgcg tacgcgcgaa ccaggtttcg ccgggctgct gcacaatgcg
    12601 atgttccggc gtcacgcgat tttggctatc aatcacaata cgtactggct ggcggagatt
    12661 ttgttgcggg tagagcgcct gagtttgttc atccagttca gaccaacgca ctgttaaggc
    12721 tggatcatcc gccagcaccg tggcgctgct ggttaaaatg gcatgacttt gtgcgcgctg
    12781 tcgttgtacg tcgcgccgcg cctgaggcga agtgatccac tggctttcgc cgctcgccat
    12841 cgccgtgcgg ccatcaagcg atgcgccaag ttttaactga atataaggaa agccggtgcg
    12901 catccgcttg agaaagcctt tattcaattg ctcggcttca ctcatcatca gcccgtggct
    12961 gacgtcaatg ccagcctgtt gcagacggta aagtccacgc ccagcgacct gcgggttagg
    13021 atcttgcatc gaggcaacca cgcgcgctac gccagcggcg atgagtgcgt cacagcacgg
    13081 tggcgtacga ccatgatggc tacagggttc gagtgtgaca taggcggtcg cacctttggc
    13141 tttttcaccc gccatacgca acgcgtgtac ttcggcatgt ggttcacccg cacgttggtg
    13201 gtaaccttca ccgacaattt cgccatcttt gacaatgacg cacccgacat tcgggttggg
    13261 atgcgtggta aaacgtcctc gttgcgccag ctttagcgcc cgcgccatgt aatactcgtc
    13321 ctgcacggct tagtcctcca ggcgcgcgat ctcttcgcca aattctttga tatcttcgaa
    13381 actgcggtag acagaggcaa aacggatata ggcgacttta tcgagctttt tcaattgctc
    13441 catcaccaga ttgccaatca tcttgctcgg tacttcgcgc tcaccggtgg cgcgcagctg
    13501 cgatttaata tgattgattg ccatttcgac gtcatcggaa ctcaccggac gtttttccag
    13561 cgcccgcagc attccgctac gcaatttctc ttcattaaac ggttcacgca cgtcgttgct
    13621 ttttacaaca cgcggcataa ccagctccgc cacttcaaag gtggtgaaac gttcattaca
    13681 caccagacac tgccgacggc ggcgtacgga tgaaccctcg cccacgagac gagagtcaat
    13741 taccttagtg tccacggcga aacagaatgg gcaatgcata cggcgtcctg accaggtggt
    13801 taacagaaat ctattttacc ctgaactgac gatacaacaa aggcgcaacg cttttgagat
    13861 aaaggatcga tgctttcgct gcttttaccc tctaccatta ggctaattgc gacgagaaag
    13921 ggacgaccta tgaatactaa cgtttttcga ctgctcctgc tgggaagcct gttcagcctt
    13981 agcgcctgtg tgcagcagag cgaagtgcga cagatgaaac acagcgtcag cacgctgaac
    14041 caggagatga cgcaactcaa taaagaaacg gtcaaaatca ctcagcaaaa caggctgaat
    14101 gcaaaatcca gcagtggggt ttaccttctg cctggagcga aaacaccggc aagactggaa
    14161 agccagatcg gtactttacg tatgtcgctg gtgaatatta cgcctgatgc agatggcacc
    14221 accctgacgc tacgtattca gggcgagtcg aatgatccct tgcccgcatt cagcggaact
    14281 gttgaatatg ggcaaattca gggaacaata gacaactttc aggaaatcaa tgtgcagaat
    14341 caattgatta atgcccctgc cagcgtcctc gcccccagcg atgttgatat tccgttacaa
    14401 ttaaagggga tttctgtgga tcagttaggc tttgtacgta tccacgacat tcaacctgtt
    14461 atgcagtaaa cgtatttcgg gacgattttg tgcgtcccgc aacatatttc cccgtcattt
    14521 tgttactctg cttacatcac ctggattgat agtaaaagtt tgcaacaagg gcgaaagtca
    14581 gtacaatccc cgcccgaatg tgtgtaaacg tgaacgcaat cgattacgta aatgatagaa
    14641 ctgtgaaacg aaacatattt ttgtgagcaa tgatttttat aataggctcc tctgtatacg
    14701 aaatatttag aaacgcaatt tgcgcctttt tcactcccgc aagggatttt caaacagtgg
    14761 catacatatg aaaaaaacat tactggcagc cggtgcggta ctggcgctct cttcgtcttt
    14821 tactgtcaac gcagctgaaa acgacaaacc gcagtatctt tccgactggt ggcaccagag
    14881 cgttaacgtt gtcggaagct atcacacccg ttttggaccg cagatccgca acgataccta
    14941 ccttgagtac gaagcattcg ctaaaaaaga ctggttcgac ttctatggtt atgcggatgc
    15001 gccggtattc ttcggcggta actccgatgc caaaggtatc tggaaccacg gctctccgct
    15061 gtttatggaa atcgaaccac gtttctccat cgacaagctg accaatactg accttagctt
    15121 cggtccgttc aaagagtggt acttcgcgaa caactacatt tacgacatgg gtcgtaataa
    15181 agatggtcgc cagagcacct ggtatatggg tctgggtacc gacatcgata ctggtctgcc
    15241 gatgagcctg tccatgaacg tctatgcgaa ataccagtgg cagaactatg gcgcagcgaa
    15301 cgaaaacgag tgggacggtt accgtttcaa aattaaatac tttgtgccga ttaccgatct
    15361 gtggggcggt cagctgagct acatcggctt caccaacttc gactggggtt ccgatttagg
    15421 ggatgacagc ggtaacgcaa tcaacggtat taagacccgt actaataact ctatcgcttc
    15481 cagccatatt ctggctctga actacgatca ctggcactac tctgtcgtag ctcgttactg
    15541 gcacgacggt ggtcagtgga acgacgatgc agaactgaac ttcggcaacg gcaacttcaa
    15601 cgttcgctct accggctggg gtggttacct ggttgtaggt tacaacttct gattatgaaa
    15661 atgccgggat ttattcccgg catttcagat tgttaacaac gtgcgctttg ttcatgccgg
    15721 atgcggcgta aacgctttgt ccgacccaca aaagcacgta aattcaatat attgctgaaa
    15781 taacgtagtc ctgataagcg tagcgcatca ggcaatttta cgttttaatc acttcttctt
    15841 gttcatcatc gctttcaggt cagcgaatgg gttgtacttc gcttcaccga catctttctg
    15901 cgcatcttcc cctgcgataa cggtcgtacc atactgatcc gcttcggtat atttcgaatg
    15961 ctcatgatcg tggcaataga gacaaagcaa ttcccagtta ctgccatctt ccgggttatt
    16021 ggtatggtcg tgatcaatgt ggtgaacagt aagttcacgc aggttggaat agacaaactc
    16081 gcgggaacag cgaccgcaga cccacggata gatttttaat gctttttcgc gatagccgct
    16141 ttctaaccgc gcatagtttt ttgggatgat agccatgaaa agttacctgg atgaaatgta
    16201 gggttacgcg cagtttccca agatgcgggg attttcgcaa tctccataca tcaaaaaaaa
    16261 tcccgatctt ctgaccggga ttttcaacat caacgggaac ttgattaagg cagaattgac
    16321 ggctgatccg ccccttcttt ttccactttc tgctgcaaca tgtgttcgcg cttcataccc
    16381 agtttcagag ccaacgcaga tgccacatag atggaagatg cagtaccgat ggaaacaccg
    16441 ataagcatgg tcagcgagaa gccttccagt accggaccac cgaagaggta cagcatcagg
    16501 ataaccatca aggtagtacc ggatgtgatc aaggtacggt gcagcgtctg ggtcaaggac
    16561 acgttaaaga tttcgtaagg cgtaccgcga cggatcttgc ggaagttttc acgaatacgg
    16621 tccgatacca cgatactgtc gttaagcgag taaccgataa ccgacatcaa cgatgccaca
    16681 atggtcaggt caatctcgat atggaataac gacaaaatac ccagcgtaat gataacgtcg
    16741 tgcgccagcg caataaccac ccctgccgcc agtcgccact caaagcggaa acctacgtac
    16801 acgaggatag acagcagcgc tgccatcaac gccatcgcac cggtttgcgc aaggtctgcc
    16861 cccacgctcg gaccgacgaa ctcaatacgc ttcactgctg cattctgatt ggtggattcg
    16921 ttaatcacct tcagaacctg gctgcccagc acctgaccgc cggtttcgcc ttcagcaggc
    16981 ggcatacgga ccatgatgtc gtggctgcta ccaaagtttt gcagcattgg ctcttcaaaa
    17041 ccggcttttt gcaatgcatc acgcattacg tcaatttcag ccggtttttc gagcgtaatt
    17101 tcgataaccg taccaccggt gaaatccagc ccccagttaa agccgcgcac gcccataata
    17161 acgatagcgg cgattaacag cagaccagag atgccgaaag cccagtagtc ccagcgcata
    17221 aagtcataga ctttacggcc gtggtttagt tgttcaacag tatattcctg tgccacatcg
    17281 cactcctcag attgacagct tcttgacgcg cttgccgcca tatagcaggt ttacgatggc
    17341 acgcgtaccg acaatcgcgg taaacatcga cgtcgccaca ccgataccgg tagtaatcgc
    17401 gaacccttta attgccccgg tacccactgc gtacaggatg atgactttaa tcagcgtggt
    17461 gatgttcgca tcgaagatag aactgaatgc gccacgataa ccttcatcaa ttgcctgttg
    17521 aacagtacgt ccgttgctca actcttcttt aatacgttcg ttgatcagta cgttcgcatc
    17581 gaccgccacc gcaagggtta agacgatacc cgcgatacct ggcatactca gcgttgcgcc
    17641 tggcaacagc gacataatgc cgacgattaa gatcaagttg gcaatcagag cactggtcgc
    17701 aatcagacca aacttcttat agaagatgat catgaacaga atagaaacca gcagaccggc
    17761 aaggcaagcc tccagcccct gttcaatgtt ctgcataccc agggttgggc caatggtacg
    17821 ttcttcaaca atctgaatcg gcgcgatcaa cgcaccggca cgcagcagca gtgacagctg
    17881 acgggcttcg ttcgggttgt tgatgccggt gatacggaag ctgttaccca gacgagactg
    17941 gatgttggcg atgttaatca cctcttcctg tttcaccaga accgcacgac catttgcatc
    18001 tttcttaccg ctgtctttgt actccacaaa cagggttgcc atcggtttgc cgatgttgtc
    18061 cttagtgaag ttagacatga tgttaccacc agcgctatcg agcgagatgt taacctgcgg
    18121 ttggttgtat tcgtcctggc tggaagtgga gtcggtgata tggtcaccgg tcagaattac
    18181 gcgtttgtac agcacaactg gctgaccttc gcgggtctgt ttcacttcag agtcgcccgg
    18241 tacgcgaccg gatgccgcag cggcctggtc aacgttggtg tttaccagac ggaattccag
    18301 cgttgccgtc gcacccagaa tctctttcgc acgcgcagtg tcctgaatac ctggcagttc
    18361 aacaacgata cggtcagcac cctgacgctg aaccaccggc tccgccacgc caagttggtt
    18421 tacacggtta cgcaggatat tgatgttctg ctgcaccgca tattcacgcg cttcactcag
    18481 acgagcatcg ctcattaccg cacgcagctg gttgctgccc tggctactaa tcaccaggtc
    18541 cggatggcgc ttgctcagat acgcaatggc ttcatcacga gctttagcat cgcggaaagt
    18601 aatgctcagg ccgtagttgt tttctttacg aacggtggta tacgggatgc ccttttcacg
    18661 cagatcgctg cgcaggctat cgatattttg ttcctggagt ttgccaagcg cggtgtccat
    18721 atccacttcc atcaggaagt gaacgccgcc acgcaggtca aggccgagct tcatcggctc
    18781 agcgtgaata gctgccagcc agcgcggcgt tgccggggca aggttaagcg ccacgacgta
    18841 tttgtcaccc ataacgccca ttaatgcttc acgagcgcgc agctgggtgt cagtggagtc
    18901 gaagcgcgca agaatagcgc cctcttccag tgccacagac ttagcagtta ttttttcttc
    18961 ttgtaacgtt ttctggacct ggatcagcgt ttgctcactg gcggcgactc cgcgcgcacc
    19021 agtgatctga acagccggat cctcaccaaa caggttggga agcgcataca gcagaccgat
    19081 gacaatcacc acgatcagca tgacgtactt ccacaaagga taacggttta acacggcaat
    19141 tcccttaggg aaaaatttta attacagcgc cttcatggtg cctttcggca ggacggcagc
    19201 tacgaagtca cgtttaataa ctacttcagt ggtgtcattc agcgcgatag caatgtagcc
    19261 gttttccgct actttggtta cgcgaccaac caggccaccg ttcgtcagaa cttcatcacc
    19321 tttggcaatg gagtccatca gctttttgtg ttctttggtg cgcttctgct gtggacgcag
    19381 gatcatgaaa tagaaaatca gaccgaatac caccagcatc aaaatcaaag acatcgggct
    19441 accttgcgcc ggtgcacccg ttgccgctac cgcatcagaa ataaaaaagc tcattaaatt
    19501 tccctcatta ttaatattaa tcaacgttca aaggtggtac ttctcgcccc tgacgctggt
    19561 aaaaatcagt tacgaagctc tctaatttac cctcttcaat agccttgcgt aaacccgcca
    19621 tcaaacgctg gtagtaacga aggttatgaa tggtgttgag tcgcgcgcct aatatttcgt
    19681 tgcaacggtc aagatgatgc aagtaagcgc gtgaataatt gcgacaggtg tagcaatcac
    19741 actcaggatc gagtgggcca gtatcgctct tatacttcgc attgcggatt ttcaccacgc
    19801 catcggtcac gaacaaatga ccatttcggg cgttgcgggt tggcattacg cagtcaaaca
    19861 tatcgatacc acgacgtacg ccttcaacca ggtcttctgg tttaccaacg cccatcaggt
    19921 aacgcggttt gtctgccgga atttgcgggc atacatgctc cagaatgcgg tgcatatctg
    19981 ctttcggctc acccacagcc agaccgccga cagcgtagcc atcaaaaccg atatctacca
    20041 gacctttaac agaaatatca cgtaaatctt cgtaaacgct gccctgaatg ataccaaaca
    20101 gcgcattttt gtttccgaga ctgtcaaaac gctcacggct acgcttcgcc caacgcagag
    20161 acatctccat ggagcgtttt gcgtaatccc agtcagcagg atacggcgta cactcatcaa
    20221 agatcatgac gatatccgaa ccaagatcgt actgaatctc cattgatttt tcaggatcga
    20281 ggaaaatcgg atcgccgttg atcgggttac ggaagtgcac gccctgttcg gtgattttac
    20341 gaatatcgcc aaggctgaag acctggaaac cgccggagtc ggtgaggatc ggccccttcc
    20401 actgcataaa atcgtgcaga tcgccgtgca gtttcatgat ttcctggccc gggcgcagcc
    20461 acaggtggaa ggtgttgccg aggataattt gcgcgccagt ggcttcaact tcttccggcg
    20521 tcatcccttt tacggtgccg taggtgccaa caggcataaa acaaggcgtt tccactacgc
    20581 cacgatcaaa gaccaggcgg ccacggcgtg cgcgaccgtc ggtggtgtcc agttcaaatt
    20641 tcattttttc tccactacgt cagaaaaaca gtccaacgtt ttaaaccagc gccgcggaat
    20701 tactccccga cgcgctcatt aattgcctgc ggattgtacg tgataaacat cgcatcaccg
    20761 taactaaaaa agcgatattt ctcttctacc gctgctttat aggcattcat ggtgtgttga
    20821 taaccggcaa aggccgaaac cagcataatc agcgtcgatt ccggcaggtg gaagtttgtc
    20881 accagcgcat cgaccacttt gtactggaag cccggataga taaagatttg ggtatcgtca
    20941 aagaacggtt cgataagatc gtttttcgcc gcctgagccg cgctttccag cgaacgtact
    21001 gaggtggtgc caaccgcaat cacccggtta ccgcgcgctt tcgccgccag taccgcgtct
    21061 accacatcct gcggcacttc agcgtattcc gagtgcatga tgtgatcttc aatggtgtcg
    21121 acgcgcaccg gctggaaggt gcccgcacca acgtgcaacg tcacaaacgc catctccacg
    21181 cctttggcgc gtaatttttc cagcaaaggt tcgtcaaaat gcagacctgc ggtcggggct
    21241 gcaaccgcgc ccggtttttc gctataaacg gtttgataaa gttcgcggtc agcgtcttcg
    21301 tccggacggt cgatatacgg cggcagcggc atatggccga tgctgttgag aatatccagc
    21361 accgagcgtt catcattaaa ttcgacttca aacagtgcgc cgtggcgcgc ggtcattgtt
    21421 gcgttaatac tttcgtcatc gcccagcagc agttctgcgc caggttttgg cgctttcgag
    21481 gcgcgaatat gcgcaagaat gcgtttgtcg tcgagcatcc gttcaaccag cacttcaatc
    21541 ttgccgccgc tggctttacg cccaaacagg cgcgccggga tcacgcgggt attattaaaa
    21601 accagaagat cgccggggtt gagcttatca agtaaatcgg tgaaagtacc gtgcgtcagc
    21661 gcgcccgtcg gcccgtccag cgacagtaaa cgacagctac tgcgttcagg catgggatag
    21721 tgggcaatca gggattcggg caattcaaag gagaaatcgg taacgcgcat gacactgact
    21781 cagactaaaa taagaggcgg gtagtctagt gccggggcgc tctccctgca acctttaccc
    21841 ccttttggat agaatataat cgatgaattt tttagctcac ctgcatttag cccatctcgc
    21901 ggaaagctcg ctttccggca atttactggc tgatttcgta cgcggaaatc ctgaagaaag
    21961 ttttccgccc gacgtcgtgg ctggcattca tatgcatcga cgtatcgacg tattaaccga
    22021 caatctgccg gaagtccgcg aagcacggga atggtttcgt agtgaaactc gccgcgttgc
    22081 gcctattacg ctggatgtca tgtgggatca ctttctttcc cgccactggt cgcagctgtc
    22141 gccggacttt ccgctacagg aatttgtctg ttatgcccgc gagcaagtga tgacgatttt
    22201 gccggactca ccgccacgtt ttatcaatct gaacaattac ttgtggtcag agcagtggct
    22261 ggtgcgctat cgcgatatgg atttcatcca gaacgtgtta aacggcatgg caagccgccg
    22321 cccacgtctg gatgccctgc gtgactcctg gtacgattta gacgctcatt atgacgccct
    22381 cgaaacccgc ttctggcagt tttatccgcg gatgatggcg caggcgtcac acaaggcgtt
    22441 ataaaacgtt agttcatcca taccgtagcc gaaatggcag gcaaagccag aatcccgttt
    22501 gtcagttgcc catggccttc tttgcgttgc cattgcgcga cattaagaaa cggtgacgcg
    22561 gggagcacca cttcacaggc ctcgccacgg ttgattgcca ccagtacacg ttgctgattc
    22621 agcacgcgga caaataccac tacgttatct tccgcataca gcacctgaca gccgccacga
    22681 cgcagcgcct gacttttctt acgcagcgca atcattcgct ggtacagcgc gaataacgcc
    22741 gtatcctgct tttccacctg ccaggggaac ggtttacggc aaaacggatc gtttttgcca
    22801 tccagtccta cttcatcacc gtaataaatg cacggtacac caggccaggt gaacagccag
    22861 accaccgcca gcggcaggcg cgcaatatcc cgaccgagca gcgttttaaa tcgcgcagta
    22921 tcgtggctgt cgagctgatt aaacatacgt aattgttgtt gatgagaaag ccctgcgcgg
    22981 taattatcca tccaggccat acaggtttgg gcatcaattt gctgcggatc gtaagagata
    23041 tcggtattgg caagaaatcc ccacaacggg aatgtgaagc cacgatagtt catggcggca
    23101 tcttccacat cggcctgtaa ccattgccgt gcatcgccaa aatgttcgcc gacaatatac
    23161 gcttccggct gggtttcttt cgccgcttcg gtgatcccag caacgtgctg catattattg
    23221 cgcgccccac ccgcctcccc cagcatatgc accacatcca gccgccagcc gtccatactc
    23281 cacggcgctt tcagccaatg gcggacaata ctgtcttccc cgcgataaat ttcattcacc
    23341 agactttccg actgataatc cagcttcggc aagctggcat agccaagcca gtcgagcgcc
    23401 gtgccatcat cactaaacga gtaccagtcg cgccagggcg attcagggtt gtgacaagct
    23461 ccccccgtgc cacgattgtg cctgtcaaac caggcatggg aatcgccact gtggttaaac
    23521 acgccatcca gcaccagccg cattcccagc tgctgcgtat tgtggcgtaa gcgcagcaac
    23581 gccccatcac cgccaaactg cggatcgaca tggcgataat cctcggtatc gtatttatgt
    23641 acgctgggag ctttaaacac cggattgaga tacagcgccg tcacgccaag ctttttcaga
    23701 tacggcagtt tttcgcttat cccgtccaga tcgccgccat agaacgttga tccgcccgcc
    23761 tgcgccgtga ccggttcatc ccagtcacgc aagatgatct cttgtccggc tgcatgatgg
    23821 taatagacat gatcctgttc agcttcacga ggaagactac gcgcaaaacg atcagggaag
    23881 atctgataaa aaatctgatc cgcagcccat tgtgggccga tatccggtac atcgacggca
    23941 aactgctcca gtcgtgccgg cggcattcgg ctgaagccct gcggtgtaaa ccaacgctgg
    24001 cgatcgtgcc acagcagttt gaaactgtaa cgccgccggg gttgtccgct ggagagatca
    24061 atcgccgcac gccatgcggt gacgccaggc tgctgctgac tgcgctgctt atgcatcgat
    24121 actgacattt cttcgttatc gtgttctgta cgcagcataa tgcgctgcgg tgggtcttcg
    24181 cccgtcagcc acagtgtaat gagcagttga tctttgcttt gtttaacaaa tgggggcacc
    24241 ggcaggtgcc atgcatttaa catcataatt cccctgtgat gaaaatctga tcaccttgcc
    24301 atagcctaat gcaggatcac tcatcatctg aaggatattt gggggaggag gacgggggcg
    24361 gataactttc ggaatagccg gatcaggatt tcctcctgaa ccggcttaca gaacgcaagg
    24421 attactggtt ttcagccagc tgacgatcgt ggcggcgttt aaacatccag ccaatcaaca
    24481 gcacaacaat ccacgcgaaa ccgacataca gcgagatacg cgtatccggg tgataaccaa
    24541 tcaacccgat aataaagagc aggaaaatca aaccgccgat ggtcgttgct accccacccg
    24601 gcactttaaa tttcagcgcc ttaacttctt ctggcggcaa acggcgacgg aaggcaattt
    24661 gcgacagcag gatcataatc cacacccaca ccgtggcgaa ggttgccagc gaagcgatca
    24721 ccaggaagac gttttccggc atgatgtagt tcagatacac cgcaaacagc agcgcggtag
    24781 tcatcaccag caccgtaacc cacggaatac cgcgacgcga cgttttgctg aaaattttcg
    24841 gcgcgctgcc ctgctctgcc ataccgtgga gcatacggcc tacgccaaat acgtcactgt
    24901 taattgccga cagcgaagca gtcagcacaa caaagttaag aatgctggcg gcaaaggtaa
    24961 tgcccatatg ctggaacgtc agcacgaacg ggctaccggc agtgccaacc tgattccacg
    25021 ggtagataga cataatgacg aacagcgtac cgacgtagaa caccagaata cgcatcggca
    25081 cggagttaat cgcacgcggt atcgattttt caggatcttt cgcttcaccg gcggtaatcc
    25141 cgataatttc gatcccaccg taagcaaaca tcaccatttg caacgacatc accatcccaa
    25201 gccagccgtt actgaagaag ccgccgttgc tccacaggtt atgaataccg gtcggttgcc
    25261 cgccgttgcc aatcccccag atgatgatgc cgaaaccggc gacaatcatg atgatgatgg
    25321 tggcgacttt aaagaacgag aaccagaatt ccagctcacc gaagaccttc acgctcatca
    25381 ggtttacggc gcaaatgatc agcaccacgc tcagtaccca aatccagtgc ggcaccgtcg
    25441 ggaaccagac acccatatag ataccaaaag cggtcacatc ggcgatggcg acaataagga
    25501 tttcaaagca ataggtccag ccggtaatgt aacctgccag cgggccgagg ttttcctgcg
    25561 cataacgcga gaaagagctg gctgccgggt tatgtaccga catttccccc agcgcacgca
    25621 taatgatata cgccgcgata ccaccgataa tataggccaa caacacgctc ggaccggcca
    25681 ttttgatggc gtctgccgaa ccgtaaaaca gcccggtgcc aattgctgaa cccagtgcca
    25741 taaagcgtat gtggcgggta cttagcccac gctttagctt gttcttactt tccatcaatt
    25801 cctaacccat caacacaata aaaaaccacg gggcatcgca gccccgtggt taaaacaaat
    25861 gttcagtgat ttagtgagcg ctggaggtca cctgacgacc tgccgcgcga tcccagataa
    25921 tggccagaac caccatcacc actgttggca ttaaccacgc cagaccttgt tcggccagcg
    25981 gtaaacgctg cgcccaggac ggtaagatat cgctgaatgc agatgctttg atcccgtcga
    26041 gaataccaaa aagcaggctg ataaacatcg gcggagcaat cacgcgggac gaattatgcc
    26101 accatgagcg tgtaaaactt aatacaacca gtgcgataca cggcggataa atagcggtca
    26161 gcaccggtac ggagatctgg atcagctggc ttaagccgag gttagaaacc accatcgaga
    26221 agccgccgag gataaacacc agcgtacgat aagagagcgg tacgtactgg gcaaagaatt
    26281 ctgcacaagc acaggtcagg ccaactgccg ttaccaggca ggcgatgaag attaacgccg
    26341 ccagcaggaa gctaccgccg ccgccaaagg tgtgctgaac gtaagcatgc agaatagcag
    26401 cgccgtttgc agactgatcg accagcgacg cgctgtctga acccagacgg aacagcgcca
    26461 ggtacagcag agtcagacca acacccgcca tcaggccagc ccagacggta taacgggtca
    26521 gcagacgcgc ttcggtaacg ccacgagaac gcgccgcgtt aacaataacg ataccaaaca
    26581 ccattgcgcc cagcgtatcc atggtcagat agccgttaac gaagccgtta gaaaacgcag
    26641 cgttttgata agcctcagtc gccgtgctga tagaacccgc cggccagaca atcgcggcaa
    26701 cagacaggat gaccagcgcg ataattttca gcggcgcaag gaagttgccc acggtatcca
    26761 gcagcttgcc cggatagagc gaaaccagaa taacgatagc gaaatagacc aggctgtaga
    26821 taaacagcgg cagcgcggaa tcaccagtca gcggcgcaat ccccacttca aaggaaacgg
    26881 tagctgtacg cggcgtagcg aaaagcggcc ccaccgccag gtaacaaacc gttgccagca
    26941 gtacgccagc gactttaccg attggcgtgc tgaggctgtc aacaccgccg ccaacttttg
    27001 ccagcgccac taccgttagt accggcagac caacggcagt aatgaggaag ccgaatgccg
    27061 cagtccagac gtgttcgcct gcctgcaagc cgaccattgg agggaaaata atgttacctg
    27121 cgccgacgaa caacgcaaat gtcataaagc ccagagcgat gatatcgcgc gatcttaatt
    27181 gatgggtcat aaatcatact gcctgtggat gtggtgttgt aacgttaaat ttttgtgcca
    27241 atccctgggg atgatacagc ggtatattta aacaatttta gcgggaaata ctcccaacca
    27301 ggcgcggcga agaatagttt ttcgatttac cgcgttaatg cagtcagtat gacagcacct
    27361 gaagcgcaat ttaaacgctt ataacgtttt aaagcaagga gggatctaaa aaccagaggt
    27421 atatagcgat aagaaatcac caaccagtat aaaacactat ttccgtgaaa aagacatggc
    27481 taatcatgcg aacaaaaaat caccaaccgt tgtaaaatct aacgcccgta ttttgactgc
    27541 aaagaaaata agccagcatc ggctggctta tggcaataaa agatgacaaa ggcggattaa
    27601 tcgctgtttt tggcaattaa acgttccggg ataacaaaac tgaaacgtgt tccttttcct
    27661 actgtactct caatattcag gcgactttcg tgatgattca ccgcatgttt cacgatcgct
    27721 aaccctaatc cgctaccgcc ggtttgccgg gaacgcgctt tatcaacgcg ataaaaacgc
    27781 tcggtcaggc gcggaatatg ctccggtgca atgcccggtc cgttatcttc aacgctaaat
    27841 tcggcaccgt gcggcactcg ctgccagcgt acggtgatat gcgtgccttc tggagtatga
    27901 ttcacggcgt tatagaccag gttcgaaatc gcactgcgta gctgatcttc gttgccagac
    27961 actttgaggc cgttatctat ctcaaaggta aatgtctgtt ttttctgact cagagtctga
    28021 gcctcacgct caacaacgcg cagcatcatc ggcacatcaa ccttttcatt gagcaaatgc
    28081 gtcggtgcgg cttctatttt cgacagcgtc agcaactgct tcaccagccc ttccatccgc
    28141 tgggtctgct cgcgcatggt gtgcaacgct ttttcgcgta ccgcgccttc cagcggctgc
    28201 tcatccatca tctccaggta accctgtaac acggtcaatg gcgtacgtaa ctcatggctc
    28261 acgttggcaa aaaagttacg ccgcgcccct tccagttgat gcatttgcgt gacatcacgc
    28321 gccaccatca gcaactgttt gtgggtataa ggcatgacgc gaatttccag atgccgcccg
    28381 gtgttgagca ccagattgag cgggcgagaa aaatcacgcg ttttcagata ttgcgtaaac
    28441 tccgggtaac gcagcaggtt aaggatgttc tgcccgttat cttccggcca gcgcaaacca
    28501 agaatttgtt gcgccagacc gttacaccag aaaataccgc cctcttcagt ggtcagcacc
    28561 actgcgtcgg gcagcgactc cgcgccgcta cgaaagcgtt taatcagatt gcccagttca
    28621 cggcggcgtt ttttatttcg cagctgcatc tggtgtaagc cgtatagtag cggttcccag
    28681 ctaccacgcc ccggtggcgg ggtcatacta cgatccaccc acagccacca tgaaaggcgc
    28741 aataaattcc agaaatgcca gataagcagt cccgttaccg atgccagcaa aaaccagggc
    28801 aggtaaccaa aaaatgcacc caggatgaaa gccgggaagc agcaaagtag cagctccagc
    28861 accagccttt tccacgacag ccgttccagc acgtaagata ctccagttaa gaaatcataa
    28921 gccctgctct gcgtccgatg agcaaggcgt taaaagcggg ttgaaaaacg atatcctgta
    28981 ccgcgcacgg tctgcaccat gcggtcatgc ccgcctggct ccagtgcttt acgtaggcga
    29041 cgaatgtgga catcgaccgt acgatcttcc acatacacgt tagttcccca gacgtggttt
    29101 aacagctgct cgcggctgta cacgcgctca ggatgcgtca taaaaaagtg cagcagttta
    29161 aattctgtcg gccccatctc cagcggctct tcgcccgcca tcactcggtg agatgtcggg
    29221 tcgagactta atccctgcat ctcaatcacc tcttccaccg ccattggcga aatacggcgc
    29281 attaccgctt tgattcgcgc caccagctcc ttcggcgaaa acggcttggt gatatagtca
    29341 tccgcgccgg tttcaaggcc gcgcacgcga tcttcttctt cccctctggc ggtcaacatc
    29401 accactggaa tatcccgggt catcgactcg cgcttgaggt gtttgatgaa ctggataccg
    29461 gagccgccag gtaacatcca gtcaaggaga attaaatccg gccagggttc attcagttga
    29521 ttcacagcac tgtcataatc ttccgcttcg accggctgaa agccattttg ttcgagcacg
    29581 aagcagacca tttcgcgaat tggagcttca tcttctacga ccagaatacg tctcgccatg
    29641 atttgccctg ttgtaataaa taggttgcga tcattaatgc gacgtcatta tgcgtcagat
    29701 ttatgacaga tttatgaaaa gctcgtcgca catatcttca ggttattgat ttccgtggcg
    29761 cagaaaaaag caaatggcac atctgtttgg gtataatcgc gcccatgctt tttcgccagg
    29821 gaatcgttat gcgcatcctt cacacctcag actggcatct cggccagaac ttctacagta
    29881 aaagccgcga agctgaacat caggcttttc ttgactggct gctggaaaca gcacaaaccc
    29941 atcaggtgga tgcgattatt gttgctggtg atgttttcga taccggctcg ccgcccagtt
    30001 acgcccgcac gttatacaac cgttttgttg tcaatttaca gcaaactggc tgtcatctgg
    30061 tggtactggc aggaaaccat gactcggtcg ccacgctgaa tgaatcgcgc gatatcatgg
    30121 cgttcctcaa tacgaccgtg gtcgccagcg ccggacatgc gccgcaaatc ttgcctcgtc
    30181 gcgacgggac gccaggcgca gtgctgtgcc ccattccgtt tttacgtccg cgtgacatta
    30241 ttaccagcca ggcggggctt aacggtattg aaaaacagca gcatttactg gcagcgatta
    30301 ccgattatta ccaacaacac tatgccgatg cctgcaaact gcgcggcgat cagcctctgc
    30361 ccatcatcgc cacgggacac ttaacgaccg tgggtgccag taaaagtgac gccgtgcgtg
    30421 acatttatat tggcacgctg gacgcgtttc cagcacaaaa ctttccacca gccgactaca
    30481 tcgcgctcgg gcatattcac cgcgcacaga ttattggcgg catggaacat gttcgctatt
    30541 gcggctctcc cattccactg agttttgatg aatgcggaaa gagtaaatat gtccatctgg
    30601 tgacattttc aaacggcaaa ttagagagcg tggaaaacct gaacgtaccg gtaacgcaac
    30661 ccatggcggt gctgaaaggc gatctggcgt cgattaccgc acagctggaa cagtggcgcg
    30721 atgtatcaca ggagccgcct gtctggctgg atatcgaaat cactactgat gagtatctgc
    30781 atgatattca gcgcaaaatc caggcattaa ccgaatcatt gcctgttgaa gtattgctgg
    30841 tacgccggag tcgtgaacag cgcgagcgtg tgttagccag ccaacagcgt gaaaccctca
    30901 gcgaactcag cgtcgaagag gtgttcaatc gccgtctggc actggaagaa ctggatgaat
    30961 cgcagcagca acgtctgcag catcttttca ccacgacgtt gcataccctc gccggagaac
    31021 acgaagcatg aaaattctca gcctgcgcct gaaaaacctg aactcattaa aaggcgaatg
    31081 gaagattgat ttcagccgcg agccgttcgc cagcaacggg ctgtttgcca ttaccggccc
    31141 aaccggtgcg gggaaaacca ccctgctgga cgccatttgt ctggcgctgt atcacgaaac
    31201 tccgcgtctc tctaacgttt cacaatcgca aaatgatctc atgacccgcg ataccgctga
    31261 atgtctggcg gaggtggagt ttgaagtgaa aggtgaagcg taccgtgcat tctggagcca
    31321 gaatcgggcg cgtaaccaac ccgacggtaa tttgcaggtg ccacgcgttg agctggcgcg
    31381 ctgcgccgac ggcaaaattc tcgccgacaa agtgaaagat aagctagaac tgacagcaac
    31441 gttaaccggg ctggattacg ggcgcttcac ccgttcgatg ctgctttcgc aggggcaatt
    31501 tgctgccttc ctgaatgcca aacccaaaga acgcgcggaa ttgctcgagg agttaaccgg
    31561 cactgaaatc tacgggcaaa tctcggcgat ggtttttgag cagcacaaat cggcccgcac
    31621 tgagctggag aagctgcaag cgcaggccag cggcgtcgcg ttgctcacgc cggaacaagt
    31681 gcaatcgctg acagcgagtt tgcaggtact tactgacgaa gaaaaacagt tacttaccgc
    31741 gcagcagcaa gaacaacaat cactaaactg gttaacgcgt ctggacgaat tgcagcaaga
    31801 agccagccgc cgtcagcagg ccttgcaaca ggcgttagcc gaagaagaaa aagcgcaacc
    31861 tcaactggcg gcgctcagtc tggcacaacc ggcacgaaat cttcgtccgc actgggaacg
    31921 catcgcagaa cacagcgcgg cgctggcgca tactcgccag cagattgaag aagtaaatac
    31981 tcgcttacag agcacaatgg cgcttcgcgc gagcattcgc caccacgcgg cgaagcagtc
    32041 agcagaatta cagcagcagc aacaaagcct gaatacctgg ttacaggaac acgaccgctt
    32101 ccgtcagtgg aacaacgaac tggcgggttg gcgtgcgcag ttctcccaac aaaccagcga
    32161 tcgcgagcat ctgcggcaat ggcagcaaca gttaacccat gctgagcaaa aacttaatgc
    32221 gcttgcggcg atcacgttga cgttaaccgc cgatgaagtt gctaccgccc tggcgcaaca
    32281 tgctgagcaa cgcccactgc gtcagcacct ggtcgcgcta catggacaga ttgttcccca
    32341 acaaaaacgt ctggcgcagt tacaggtcgc tatccagaat gtcacgcaag aacagacgca
    32401 acgtaacgcc gcacttaacg aaatgcgcca gcgttataaa gaaaagacgc agcaacttgc
    32461 cgatgtgaaa accatttgcg agcaggaagc gcgcatcaaa acgctggaag ctcaacgtgc
    32521 acagttacag gcgggtcagc cttgtccact ttgtggttcc accagccacc cggcggtcga
    32581 ggcgtatcag gcgctggagc ctggtgttaa tcagtctcga ttactggcgc tggaaaacga
    32641 agttaaaaag ctcggcgaag aaggtgcggc gctgcgcggg caactggacg ccttaacaaa
    32701 gcagcttcag cgcgatgaaa acgaagcgca aagcctccga caagatgagc aagcacttac
    32761 tcaacaatgg caagccgtca cggccagcct caatatcacc ttgcagccac aggacgatat
    32821 tcaaccgtgg ctggatgcac aagatgagca cgaacgccag ctgcggttac tcagccaacg
    32881 acatgaatta caagggcaga ttgccgcgca taatcagcaa attatccagt atcaacagca
    32941 aattgaacaa cgccagcagc agctcttaac ggcattggcg ggttatgcac tgacattgcc
    33001 acaggaagat gaagaagaga gctggttggc gacacgtcag caagaagcgc agagctggca
    33061 gcaacgccag aacgaattaa ccgcgctgca aaaccgtatt cagcagctga cgccgattct
    33121 ggaaacgttg ccgcaaagtg atgatctccc gcacagcgaa gaaactgtgg cgctggataa
    33181 ctggcggcag gttcatgaac aatgtctcgc attacacagc cagcagcaga cgttacagca
    33241 acaggatgtt ctggcggcgc aaagtctgca aaaagcccag gcgcagtttg acaccgcgct
    33301 acaggccagc gtctttgacg atcagcaggc gttccttgcg gcgctaatgg atgaacaaac
    33361 actaacgcag ctggaacagc tcaagcagaa tctggaaaac cagcgccgtc aggcgcaaac
    33421 gctggtcact cagacagcag aaacgctggc acagcatcaa caacaccgac ctgacgggtt
    33481 ggctctcact gtgacggtgg agcagattca gcaagagtta gcgcaaactc accaaaagtt
    33541 gcgtgaaaac accacgagtc aaggcgagat tcgccagcag ctgaagcagg atgcagataa
    33601 ccgtcagcaa caacaaacct taatgcagca aattgctcaa atgacgcagc aggttgagga
    33661 ctggggatat ctgaattcgc taataggttc caaagagggc gataaattcc gcaagtttgc
    33721 ccaggggctg acgctggata atttagtcca tctcgctaat cagcaactta cccggctgca
    33781 cgggcgctat ctgttacagc gcaaagccag cgaggcgctg gaagtcgagg ttgttgatac
    33841 ctggcaggca gatgcggtac gcgatacccg taccctttcc ggcggcgaaa gtttcctcgt
    33901 tagtctggcg ctggcgctgg cgctttcgga tctggtcagc cataaaacac gtattgactc
    33961 gctgttcctt gatgaaggtt ttggcacgct ggatagcgaa acgctggata ccgcccttga
    34021 tgcgctggat gccctgaacg ccagtggcaa aaccatcggt gtgattagcc acgtagaagc
    34081 gatgaaagag cgtattccgg tgcagatcaa agtgaaaaag atcaacggcc tgggctacag
    34141 caaactggaa agtacgtttg cagtgaaata actattcagc aggataatga atacagaggg
    34201 gcgaattatc tcttggcctt gctggtcgtt atcctgcaag ctatcacttt attggctacg
    34261 gtgattggta gccgttctgg tagttgtgat ggtggtatga aaaaagtcat tttatctttg
    34321 gctctgggca cgtttggttt ggggatggcc gaatttggca ttatgggcgt gctcacggag
    34381 ctggcgcata acgtaggaat ttcgattcct gctgccgggc atatgatctc gtattatgcg
    34441 ctgggagtgg tggtcggtgc gccaatcatc gcactctttt ccagccgcta ctcactcaaa
    34501 catatcttgt tgtttctggt ggcgttgtgc gtcattggca acgccatgtt cacgctctct
    34561 tcgtcttacc tgatgcttgc cattggtcgc ctggtttccg gctttccgca tggcgcattt
    34621 tttggcgtcg gcgcgatcgt gttatcaaaa attatcaaac ccggaaaagt caccgccgcc
    34681 gtggcgggga tggtttccgg gatgacagtc gccaatttgc tgggcattcc gctgggaacg
    34741 tatttaagtc aggaatttag ctggcgttac acctttttat tgatcgctgt ttttaatatt
    34801 gcggtgatgg catcggtcta tttttgggtg ccggatattc gcgacgaggc gaaaggaaag
    34861 ctgcgcgaac aatttcactt tttacgcagc ccggccccgt ggttaatttt cgccgccacg
    34921 atgtttggca acgcaggtgt gtttgcctgg ttcagctacg taaagccata catgatgttt
    34981 atttccggtt tttcggaaac ggcgatgacc tttattatga tgttagttgg gctagggatg
    35041 gtgttgggaa atatgctaag tggcaggatt tcaggacgtt attcaccact gcgcattgca
    35101 gcagtgactg actttataat tgtactggca ctgctgatgc tctttttctg cggcggcatg
    35161 aaaacaacgt cgcttatttt tgcttttatt tgttgcgcgg gattatttgc cctttcagca
    35221 cctctgcaaa tattgttact gcaaaatgcc aaaggcggag agttattagg tgccgcaggt
    35281 gggcaaatag cgtttaacct cggtagcgcc gtcggcgcat attgcggtgg tatgatgctg
    35341 acgctggggc tggcatataa ttacgtggcg ctgcctgccg ccctgctttc gtttgctgcg
    35401 atgtcatcgt tgctgctgta tggtcgctat aagcgccagc aagcggcgga tagtccggtg
    35461 ctggcgaaac cactggggta gattactgtc acggtgcgcg ttgcttattg ccggatgcgg
    35521 cgtgaacgcc ttatccgccc tacgcggttc tggcacattt tgtaggcctg ataagacgcg
    35581 gcaagcgtcg catcaggcat gatgcgccaa ttgcctggtt tttttactct tgtggccata
    35641 accacgcagc gccgcgtacg ccgctggaat caccgtgctt cgccttacgc actggcgttt
    35701 cacattcgcc gccgaagaca aattgtttaa tcaactgccc aaccgtttga tataaacggt
    35761 ctacattgct catcccgccc cccaggacaa ttacatccgg atcgagaata ttcacgacat
    35821 gtgccagcga ttttgccagc cgcagctcgt agcgacgcaa tgccagttcc gctaccggat
    35881 cgctttcttc aaccaggctg ataatttcac tgcctttcag cgcatgtccg ctcaaacgac
    35941 gataatctgt ggcaaatccc gtgcccgaaa taaaggtttc aatacaacct tgtttaccgc
    36001 aataacaagg gacttcctcg cgataacgca gttcgtcttc gtccatccaa ggtagcggat
    36061 tgtgtcccca ctcgcctgcc gtgccattgc cgccgatatg cgcccgccca ttgaatgcca
    36121 cgcccgcgcc gcatcccgtg ccgataatca cggcaaatac cgtctgtgct cccgctgccg
    36181 cgccatctac tgcttctgaa acggccagac agttggcgtc atttgccagc cgcacttccc
    36241 gctgcaaccg cgcgcttaag tctttatcga atggctgacc gttgagccag gttgaattgg
    36301 catttttcac cacgccggtg tagggcgaaa ttgagccagg aatgcccata cctaccgttc
    36361 cgcgctgccc tgtcgcctgc tccgccatat caaccaacgt ggcgatcgtt tcaatagtct
    36421 gccggtaatc atcacgcggc gtgggcagac gatggcggta caactgctcc cctgcatcgc
    36481 ccagtgcaat cacttcagtt ttggtgccgc ctaaatcgat acctatacgc acggtactct
    36541 ccttattttt ttcaatatca atagcgtaga gacggacaac cggattggca atgcaaggcc
    36601 gccgacaatt cgttatcatg cccgctaaat ttaacgacaa ggccgtggaa attatcatgc
    36661 tgtggttcaa aaatttaatg gtttaccgtc ttagccgcga gatttcgctg cgtgcagaag
    36721 agatggaaaa acagctagcc tcgatggcat ttaccccatg tggcagccag gacatggcga
    36781 agatgggctg ggttcctccg atgggatcgc acagcgatgc gttaacgcac gttgccaatg
    36841 gtcaaattgt tatctgcgca cgcaaagaag aaaaaatcct cccgtctccg gtgattaaac
    36901 aggcgctgga agcgaaaatc gccaaactgg aagcggaaca ggcgcgtaag ctgaagaaaa
    36961 ccgaaaaaga ttcgctgaaa gacgaagtgc tgcactctct gctgccgcga gctttcagcc
    37021 gttttagcca gacaatgatg tggatcgaca cggttaatgg tttgattatg gtggactgcg
    37081 ccagcgccaa aaaagcggaa gatacgctgg cattactgcg taaaagcctg gggtcgttac
    37141 ctgttgtacc attgagcatg gaaaacccga ttgaactgac gctaaccgaa tgggttcgct
    37201 ccggtagcgc agcacagggc ttccagttgc ttgatgaagc cgagctgaaa tcgttgctgg
    37261 aagatggcgg cgtgatccgt gcgaagaaac aagatctgac cagcgaagag atcaccaatc
    37321 acatcgaagc cggaaaagtg gtgactaaac tggcgctcga ctggcagcag cgcattcagt
    37381 ttgtgatgtg cgacgatggt tcgctcaagc gtctgaagtt ctgcgacgag ctgcgcgatc
    37441 aaaacgaaga tatcgaccgt gaagatttcg cccagcgttt tgatgccgat ttcatcctga
    37501 tgactggtga actggcagcg ttaattcaaa acctgattga aggattaggt ggcgaagcac
    37561 aacgttaatt gctgattttc ctttaatgcc ggatgcgacg cctgccgcgt cttatccggc
    37621 gtacgatgcc acaccaggca tataattatt cgctacggcg ggcaataatt tttagcgcag
    37681 caatattatg cgttttacgc cgtaactgat ctaatcgcct catccctatt cgcctgtcag
    37741 cagcacgcag aatattcact aacccccatt tatcgctggt aaattgtttt gttaacaact
    37801 ccgcttttgg ggtgtcaata tattcacgca ataaatcaga aattgaacaa atatccgtca
    37861 ggtaaggata ccagcaagtt tcaccgtgaa aattacgcac tccaccgtta cctgcaataa
    37921 agtctttcgg gtaatcccag atcacgtttt tatccaacgt gatccaataa cgcggtaaat
    37981 cggtgcttcc accattttgg ctgcgcatgg gataacgggt acagtgaatt tgcaggttga
    38041 tcgttggcgt cagtaattca tagatctccc gctgtaactt gctccagggg gcgttgtgtc
    38101 atcagttccg caaaaaatac ctggagatct tcactgatat ttatatcaac cttgatgaat
    38161 tatgaatata tcggaaattg aaaaaatcga agcaaaggaa atattattat gggttaaaga
    38221 gaggatattt cagaaaaatg ccctcccgtt caaggggaag gcgaggaatt acagatagcg
    38281 gcacagataa gaggtgggtt cggcaacttg cagatgaaac tcactgtgac cgggaacatt
    38341 aaacaccgaa ccggcttcat acacctgcca gtcggtcgcg tcaggcagta acacattcag
    38401 cgcgccactg attaccgtca tctcttccgg ctcagcggtg ctgaaggtgt attcgccttc
    38461 aaccataaca cccacgctgg cgcgaccagt gctgctgctg gaaaagccga ttgatttcac
    38521 tttgccggaa aagtactcat tactttgaag cataaactgg ccctgtctgg tagttgaaca
    38581 tctacttcac tataggggcc agaggcgctg actgtcacgc aaaattacac cagtaattcc
    38641 gcagccagcc gtgcaatcaa tacgttagac agcaagacag gaacatcgag ctgtttttgc
    38701 agtaaatcgc gatgacgttg gtgaaatcct aaacaatcca gcatgatgac atcagcccct
    38761 tttgccagta attctttccc ggcatcaatg attttttgtt ctgaatcatg aatggggtta
    38821 cccaatgaaa ataccggcga tttctgcaaa atttgccatt tttgcgcctg aacgggcagc
    38881 atctcctcaa ccggaacgat aacccccact tgatgatctt caacaataga ggaaaccagc
    38941 ggtggcaata tccgcgacgg ctcaagaaag atcgtattac gcgcagtcat actactaatg
    39001 tttgccgtac tcattaatat aatgacgtcg taaccccgat tatcgagtac ttcaaccaca
    39061 ccttgcaggt cacgctccac tttgcgacgc gaaacatggg ccagctggtt gtcatttaat
    39121 aatgtgagaa tggtgtcttc gcctgcttct ggcgcgtact ccgccatcac ttcttcacga
    39181 cttaacttcc ccagcaggct atgatgggaa atattatctt cgtcaatgta ttccgtcagg
    39241 agcggcaaaa cttcctgcat aggtacaatg ccgatggtca ggatcgccaa cgacgcactc
    39301 attgttcatc caccttactt ttctttcgtc gttaattacc gggcaagtgt gaagcaccac
    39361 tgctgacact tacttgtgct acaaatgaca aaaagcgtag cagcagacgt gcacggcata
    39421 atgtaaagat tccaaatgat tccagtaatg gattgttatt gtttaatatt ctaattatta
    39481 gaaaaacatg aattatgaaa aatgtgacgc agatcccttg tagtggcact cagaatccct
    39541 tccgagcagt ctgatgcggt cactctttgt cagggtcctc atagcgtttt ttcgcatcca
    39601 tcgcttcctg agccgtcgga tgttcactga tcaacgagtc tggtttagga tgatcggctc
    39661 tgagttggta ccaggttacc gtctgtcctg gctttccttt ttcaatcgtc actatatatg
    39721 cttcacgagg ataaggcggt ttcgttggca tcgttcttcc ttatttcacg ggatgaacgt
    39781 taagtatagg cgctctaaaa tcaacaattg atcgtctgtg ccagggcgct acgaatttca
    39841 gaaatcacct ggctgggttc gtttgttgcg tcgatgataa tatgcgcaac ttcgcgatat
    39901 agcgcatcgc gttcttccag cacttcctga acttcttcgc tcagcggttt tcccgttaag
    39961 gttggccgta aatcttcttc cggtgcagct tgcagtcggt taaccaggac tgatactggc
    40021 gcacacaaat aaaccacgat cccgttattt tgcataaagt gacgattaaa ttccgtcaga
    40081 ataatgccgc cgcctgtagc gataacggtg gatggcgcag ttaccgcttc cagcgccgcc
    40141 gtttctctgg cgcgaaatcc cgcccactct tccctttcga cgatctccgc gaccgtcata
    40201 ttgagctgtg attgcaacca ctgatcggta tcgacaaacc gacggttaag cgaatcggca
    40261 agggccattc cgaccgttgt tttaccacag ccccgaggcc cgatcagaaa aagaggttgt
    40321 gtcatcgtgg gttttcccca ataggtcgca atgcggcgaa agccggtgtc atgagaatag
    40381 cgatcatacc atcaaactag tacaatttcg attgtaaaga aaaaattcca cttaaagtga
    40441 aa
//
LOCUS       DAPGUL010000033        39276 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.033, whole genome shotgun sequence.
ACCESSION   DAPGUL010000033 DAPGUL010000000
VERSION     DAPGUL010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 39276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39276
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.033"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..2123)
                     /locus_tag="RHX21_001874"
     CDS             complement(<1..2123)
                     /locus_tag="RHX21_001874"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004149036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase"
                     /protein_id="HDV1987059.1"
                     /translation="MVSVTNNKQTPTESDDIDLGKIVGELIDHRKLIFAITTAFTVIA
                     VLYALLATPIYQSTALIQVEQKQGNVILDSLSQMLPDSQPQSAPEIALIQSRMILGKT
                     VDDLNLQAEIEPKYFPIFGRGLARLLGKEPGTISVSRFYLDSGSNDVPSEVTLTILGE
                     NNFEIEREGYSLKGKKGVLLEDKGVSILVDSIDAEAGSQFKITYISRLKAISNLLESL
                     NVADQGKDTGMLNLTFTGDNPTLISQVLSSITQNYLAQNVARQAAQDAKSLEFLNEQL
                     PKVRTDLDAAEDKLNSYRKQKDSVDLTMEAKSVLDQIVNVDNQLNELTFREAEISQLY
                     TKEHPTYKALMEKKQTLQTERNKLNKKVSSMPSTQQEVLRLSRDVESGRAVYLQLLSR
                     QQELNIAKSSAIGNVRIIDNAITEPEPVRPKKILVIVLGIIIGLFFSVGFVFVRVFLR
                     RGIESPEQLEEMGINVYASIPVSEWLTKNTNKNKRQKNESDKLLSVENPADLAVEAIR
                     SLRTSLHFAMMESKNNILMISGASPNAGKTFVSTNLAATIAMTGKKVLFIDSDLRKGY
                     VHKMLGSKNVKGLSDILSGQAKVESIIERVSEGDFDYICRGQTPPNPAELLMHPRFKE
                     LLSWASQNYELVIVDTPPILAVTDAAIIGKYAGTTLLVARFEANTAKEIAVSIKRFEQ
                     TGVVIKGCILNCVMKKASSYYSYGY"
     gene            complement(2140..2574)
                     /locus_tag="RHX21_001875"
     CDS             complement(2140..2574)
                     /locus_tag="RHX21_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019704361.1"
                     /note="Wzb shows phosphatase activity towards the
                     autophosphorylated Wzc protein, which induces colanic acid
                     biosynthesis; catalyzes the phosphorylation of UDP-glucose
                     dehydrogenase, an enzyme involved in colanic acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein tyrosine phosphatase"
                     /protein_id="HDV1987060.1"
                     /translation="MFNSVLVICTGNICRSPIAERLLQKLMPKKKIASAGVGALIGNS
                     ADPSAIAVAEKYHLSLDGHVGKQLSSSMARQYDLILVMEKHHLEQVTHISPESRGKTM
                     LLGHWMGGKEIPDPYRKSDEAFDLVYQLINQACRSWAEKMGQ"
     gene            complement(2580..3713)
                     /locus_tag="RHX21_001876"
     CDS             complement(2580..3713)
                     /locus_tag="RHX21_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001775085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide export protein"
                     /protein_id="HDV1987061.1"
                     /translation="MKKKLVRFSALALAIGFLSGCTIIPGQELNILRKNVVELPDSDY
                     DLDKLVNVYPMTPSLVDQLRPETVLARPNPQLDNLLRSYEYRIGVGDVLMVTVWDHPE
                     LTTPAGQYRSASDTGNWVNSDGTIFYPYIGKVQVAGKTISQVRQDIASRLTTYIESPQ
                     VDVSIAAFRSQKTYVTGEVMKSGQQPITNIPLTVMDAINNAGGLAPDADWRNVVLTHN
                     GKDTKISLYALMQKGDLSQNHLLYPGDILFIPRNDDLKVFVMGEVVKQATMKMDRSGM
                     TLAEALGNAEGISQAMSDATGVFVIRQLKGDKTGKIANIYQLNAQDASAMVLATEFQL
                     QPYDIVYVTTAPLVRWNRVISQLVPTITGVHDMTEAGKFIRTW"
     gene            complement(3859..5298)
                     /locus_tag="RHX21_001877"
                     /pseudo
     CDS             complement(3859..5298)
                     /locus_tag="RHX21_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227870.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="capsule assembly Wzi family protein"
     gene            5589..5711
                     /locus_tag="RHX21_001878"
     CDS             5589..5711
                     /locus_tag="RHX21_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987062.1"
                     /translation="MMIILTGSIFTAVEENLCVAASGFSNATAPGLAVTSALTT"
     gene            complement(6239..6752)
                     /locus_tag="RHX21_001879"
                     /pseudo
     CDS             complement(6239..6752)
                     /locus_tag="RHX21_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227873.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
     gene            complement(7145..8035)
                     /gene="galF"
                     /locus_tag="RHX21_001880"
     CDS             complement(7145..8035)
                     /gene="galF"
                     /locus_tag="RHX21_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GalU regulator GalF"
                     /protein_id="HDV1987063.1"
                     /translation="MANLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEI
                     VAAGIKEIVLVTHSSKNAVENHFDTSYELEALLEQRVKRQLLAEVQAICPPGVTIMNV
                     RQAQPLGLGHSILCARPVVGDNPFVVLLPDIILDGGTADPLRYNLAALIARFNETGRS
                     QVLAKRIPGDLSEYSVIQTKEPMVAEGQVARIVEFIEKPDEPQTLDSDLMAVGRYVLS
                     ADIWAELERTEPGAWGRIQLTDAIAELAKKQSVDAMLMTGESYDCGKKMGYMQAFVTY
                     GMRNLKEGAKFRESIKKLLA"
     gene            8794..10377
                     /locus_tag="RHX21_001881"
     CDS             8794..10377
                     /locus_tag="RHX21_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416567.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HDV1987064.1"
                     /translation="MEWIADPSIWVGLVTLVIIELVLGIDNLVFIAILAEKLPPAHRD
                     RARITGLMLAMVMRLLLLTSISWLVTLTQPLFSFRSFTFSARDLIMLFGGFFLLFKAT
                     IELSERLEGKDSNNPTQRKGAKFWGVVTQIVVLDAIFSLDSVVTAIGMVDHLLVMMAA
                     VVIAISLMLMASKPLTQFVNSHPTIVILCLSFLLMIGFSLVAEGFGFVIPKGYLYAAI
                     GFSVMIEVLNQLAIFNRRRFLSANQTLRQRTTEAVMRLLSGQKEDAELDAETASMLLD
                     HGNQQIFNPQERRMIERVLNLNQRTVSSIMTSRHDIEHIDLNAPEEEIRQLLERNQHT
                     RLVVTDGDDAEDLLGVVHVIDLLQQSLRGEPLNLRVLIRQPLVFPETLPLLPALEQFR
                     NARTHFAFVVDEFGSVEGIVTLSDVTETIAGNLPNEVEEIDARHDIQKNADGSWTANG
                     HMPLEDLVQYVPLPLDEKREYHTIAGLLMEYLQRIPKPGEEVQVGDYLLKTLQVESHR
                     VQKVQIIPLREDGEMEYEV"
     gene            10452..10790
                     /locus_tag="RHX21_001882"
     CDS             10452..10790
                     /locus_tag="RHX21_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDV1987065.1"
                     /translation="MRKKLAFLDTSLDDLRAFPESSRQEIGYQLGRIQQGLNPYDWKP
                     FSTIGPGVREIRTRDADGIYRVMYVAKFEEAVYVLHCFQKKTQTTSQSDIDLAKRRYK
                     ELVQERKNEN"
     gene            10780..11070
                     /locus_tag="RHX21_001883"
     CDS             10780..11070
                     /locus_tag="RHX21_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDV1987066.1"
                     /translation="MKIETFDSVWDAVSDTPGQAENMRIRAELVTIINNWIEQQGFNQ
                     AQAASALGVTQPRISELARGKIQIFSIDKLITMMAHAGLHIQRIEIQYPHAA"
     gene            complement(11123..12976)
                     /gene="asmA"
                     /locus_tag="RHX21_001884"
     CDS             complement(11123..12976)
                     /gene="asmA"
                     /locus_tag="RHX21_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane assembly protein AsmA"
                     /protein_id="HDV1987067.1"
                     /translation="MRRFLTTLMILLVVLVVGLSALVLLVNPNDFRDYMVKQVAARSG
                     YQLQLDGPLRWHVWPQLSILSGRMSLTAQGASQPLVRADNMRLDVALLPLLSHQLSVK
                     QVMLKGAVIQLTPQTEAVRSEDAPVAPRDNTLPDLSDDRGWSFDISSLKVADSVLVFQ
                     HEDDEQVTIRNIRLQMEQDPQHRGSFEFSGRVNRDQRDLTISLNGTVDASDYPHDLTA
                     AIEQVNWQLQGADLPKQGIQGQGSFQAQWQESHKRLSFNQISLTANDSTLSGQAQVTL
                     TEKPEWQLRLQFPQLNLDNLIPLNETANGENGAAQQGQSQSTLPRPVISSRIDEPAYQ
                     GLQGFTADILLQASNVRWRGMNFTDVATQMTNKSGLLEITQLQGKLNGGQVSLPGTLD
                     ATSINPRINFQPRLENVEIGTILKAFNYPISLTGKMSLAGDFSGADIDADAFRHNWQG
                     QAHVEMTDTRMEGMNFQQMIQQAVERNGGDVKAAENFDNVTRLDRFTTDLTLKDGVVT
                     LNDMQGQSPVLALTGEGMLNLADQTCDTQFDIRVIGGWNGESKLIDFLKEMPVPLRVY
                     GNWQQLNYSLQVDQLLRKHLQDEAKRRLNDWAERNKDSRNGKDVKKLLEKM"
     gene            complement(12998..13579)
                     /gene="dcd"
                     /locus_tag="RHX21_001885"
     CDS             complement(12998..13579)
                     /gene="dcd"
                     /locus_tag="RHX21_001885"
                     /EC_number="3.5.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCTP deaminase"
                     /protein_id="HDV1987068.1"
                     /translation="MRLCDRDIEAWLDEGRLSINPRPPVERINGATVDVRLGNKFRTF
                     RGHTAAFIDLSGPKDEVSAALDRVMSDEIVLDEGEAFYLHPGELALAVTLESVTLPAD
                     LVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSF
                     EPLSGPAARPYNRREDAKYRNQQGAVASRIDKD"
     gene            complement(13671..14312)
                     /gene="udk"
                     /locus_tag="RHX21_001886"
     CDS             complement(13671..14312)
                     /gene="udk"
                     /locus_tag="RHX21_001886"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HDV1987069.1"
                     /translation="MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVI
                     PEDCYYKDQSHLSMEERVKTNYDHPSAMDHSLLLEHLQALKRGSAIDLPVYSYVEHTR
                     MKETVTVEPKKVIILEGILLLTDARLRDELNFSIFVDTPLDICLMRRIKRDVNERGRS
                     MDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE"
     gene            14630..17947
                     /locus_tag="RHX21_001887"
     CDS             14630..17947
                     /locus_tag="RHX21_001887"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HDV1987070.1"
                     /translation="MSKQSQHVLIALPHPLLHLVSLGLVSFIFTLFSLELSQFGTQLA
                     PLWFPTSIMMVAFYRHAGRMWPGIALSCSLGNIAASILLFSTSSLNMTWTTINIVEAV
                     VGAVLLRKLLPWYNPLQNLADWLRLALGSAIVPPLLGGVLVVLLTPGDDPLRAFLIWV
                     LSESIGALALVPLGLLFKPHYLLRHRNPRLLFESLLTLAITLTLSWLSMLYLPWPFTF
                     IIVLLMWSAVRLPRMEAFLIFLTTVMMVSLMMAADPSLLATPRTYLMSHMPWLPFLLI
                     LLPANIMTMVMYAFRAERKHISESETRFRNAMEYSAIGMALVGTEGQWLQSNKALCQF
                     LGYSQEELRGLTFQQLTWPEDLNKDLQQVEKLISGEINTYSMEKRYYNRNGDVVWALL
                     AVSLVRHTDGTPLYFIAQIEDINELKRTEQVNQQLMERITLANEAGGIGIWEWVLKPN
                     IYSWDKRMFELYEIPPHIKPNWQVWYECVLPEDRQHAEKVIRDSLQSRSPFKLEFRIA
                     VKDGIRHIRALANRELNKEGEVERLLGINIDMTEVKQLNEALFQEKERLHITLDSIGE
                     AVVCIDMAMKITFMNPVAEKMSGWTQEEALGVPLLTVLHITFGDNGPLMENIYSADTS
                     RSAIEQDVVLHCRSGGSYDVHYSITPLSTLDGSNIGSVLVIQDVTESRKMLRQLSYSA
                     SHDALTHLANLASFEKQLRILLQTVNSTHQRHALVFIDLDRFKAVNDSAGHAAGDALL
                     RELASLMLSMLRSSDVLARLGGDEFGLLLPDCNVESARFIATRIISAVNDYHFIWEGR
                     VHRVGASAGITLIDDNNHQAAEVMSQADIACYASKNGGRGRVTVYEPQQAAAHSERAV
                     MSLDEQWRMIKENQLMMIAHGIASPRIPQARNLWLISLKLWSCEGEIIDEQTFRRSFS
                     DPALSHALDRRVFHDFFQQAAKAVTSKGLSIALPLSVAGLSSTTLVNELLEQLENSPL
                     PPRLLHLIIPADAILDHAESVQKLRLAGCRIVFSQVGRDLQIFNSLKVNMADYLLLDG
                     ELCANVQGNLMDEMLITIIQGHAQRLGMKTIAGPVVLPLVMDTLSGIGVDLIYGDVIA
                     DAQPLDLLVNSSYFAIN"
     gene            complement(17985..18842)
                     /gene="alkA"
                     /locus_tag="RHX21_001888"
     CDS             complement(17985..18842)
                     /gene="alkA"
                     /locus_tag="RHX21_001888"
                     /EC_number="3.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase 2"
                     /protein_id="HDV1987071.1"
                     /translation="MYTLNWQPPYDWSWMLGFLAARAVNGVETVADDYYARSLAVGEY
                     RGVVTAIPDIARHTLHINLSAGLEPVAAECLAKMSRLFDLQCNPQIVNGALGKLGAAR
                     PGLRLPGSVDASEQGVRAILGQLVSVAMAAKLTARVAQLYGERLDDFPDYVCFPTPQR
                     LAAADPQALKALGMPLKRAEALIHLANAALEGTLPMTIPGDVEQAMKTLQTFPGIGRW
                     TANYFALRGWQVKDVFLPDDYLIKQRFPGMTPAQIRRYAERWKPWRSYALLHIWYTEG
                     WQPDGTDEL"
     gene            18976..20328
                     /gene="yegD"
                     /locus_tag="RHX21_001889"
     CDS             18976..20328
                     /gene="yegD"
                     /locus_tag="RHX21_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416573.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HDV1987072.1"
                     /translation="MFIGFDYGTANCSVAVMRDGKPQLLKMENDSTLLPSMLCAPTRE
                     AVSEWLYRHHDVPADDDETQALLRRAIRYNREEDIDVTAKSVQFGLSSLAQYIDDPEE
                     VWFVKSPKSFLGASGLKPQQVALFEDLVCAMMLHIRQQAQAQLPDAITQAVIGRPINF
                     QGLGGDEANTQAQGILERAAKRAGFKDVVFQYEPVAAGLDYEATLQEEKRVLVVDIGG
                     GTTDCSLLLMGPQWRSRLDREASLLGHSGCRIGGNDLDIALAFKNLMPLLGMGGETEK
                     GIALPILPWWNAVAINDVPAQSDFYSSANGRLLNDLVRDAREPEKVALLQKVWRQRLS
                     YRLVRSAEESKIALSSVAETRASLPFISDELATLISQQGLESALNQPLARILEQVQLA
                     LDNAQEKPDVIYLTGGSARSPLIKKALTEQLPGIPIAGGDDFGSVTAGLARWAEVVFR
                     "
     gene            complement(20341..22283)
                     /gene="yegI"
                     /locus_tag="RHX21_001890"
                     /pseudo
     CDS             complement(20341..22283)
                     /gene="yegI"
                     /locus_tag="RHX21_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310906.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase YegI"
     gene            complement(22280..23041)
                     /gene="pphC"
                     /locus_tag="RHX21_001891"
     CDS             complement(22280..23041)
                     /gene="pphC"
                     /locus_tag="RHX21_001891"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase PphC"
                     /protein_id="HDV1987073.1"
                     /translation="MSWRLVYASAVGTSHISADLSCQDACQMQVAWLEDQQPLLSVFV
                     ADGAGSVSQGGEGAMLAVNEAMAYMSQKVQGGELGLNDVLATDIVLTIRQRLFAEAEA
                     KELAVRDFACTFLGLISSANGTLIMQIGDGGVVVDLGHGLQLPLTPMVGEYANMTHFI
                     TDDDAVSRLETYTSTERAHKVAAFTDGIQRLALNMLDNSPHVPFFTPFFNGLASATQE
                     QLDLLPELLKQFLSSPAVNERTDDDKTLALALWLP"
     gene            complement(23038..23697)
                     /locus_tag="RHX21_001892"
     CDS             complement(23038..23697)
                     /locus_tag="RHX21_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDV1987074.1"
                     /translation="MSEQITFATSDFASNPEPRCPCILLLDVSGSMNGRPINELNAGL
                     VTFRDELLADSLALKRVELGIVTFGPVHVEQPFTSAANFFPPILFAHGDTPMGAAITK
                     ALNMVEERKREYRANGISYYRPWIFLITDGAPTDEWQAAANKVFQGEEDKKFAFFSIG
                     VQGADMKTLAQISVRQPLPLQGLQFRELFSWLSSSLRSVSRSTPGTEVVLEAPKGWTS
                     V"
     gene            complement(23919..23978)
                     /gene="ibsA"
                     /locus_tag="RHX21_001893"
     CDS             complement(23919..23978)
                     /gene="ibsA"
                     /locus_tag="RHX21_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin IbsA"
                     /protein_id="HDV1987075.1"
                     /translation="MMKHVIILVILLVISFQAY"
     gene            complement(24251..24307)
                     /locus_tag="RHX21_001894"
     CDS             complement(24251..24307)
                     /locus_tag="RHX21_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HDV1987076.1"
                     /translation="MMKLLIIVVLLVISWPAY"
     gene            complement(24579..24635)
                     /locus_tag="RHX21_001895"
     CDS             complement(24579..24635)
                     /locus_tag="RHX21_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HDV1987077.1"
                     /translation="MMKLLIIVVLLVISYPAY"
     gene            24914..26161
                     /gene="mdtA"
                     /locus_tag="RHX21_001896"
     CDS             24914..26161
                     /gene="mdtA"
                     /locus_tag="RHX21_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter subunit MdtA"
                     /protein_id="HDV1987078.1"
                     /translation="MKGSYKSRWVIVIVVVIAAIAAFWFWQGRNDSQSAAPGATKQAQ
                     QSPAGGRRGMRSGPLAPVQAATAVEQAVPRYLTGLGTITAANTVTVRSRVDGQLMALH
                     FQEGQQVKAGDLLAEIDPSQFKVALAQAQGQLAKDKATLANARRDLARYQQLAKTNLV
                     SRQELDAQQALVSETEGTIKADEASVASAQLQLDWSRITAPVDGRVGLKQVDVGNQIS
                     SGDTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGKPLVVEAWDRTNSKKLSEGTL
                     LSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVDTEQNAVVIPTAALQMGNE
                     GHFVWVLNSENKVSKHLVTPGIQDSQKVVIRAGISAGDRVVTDGIDRLTEGAKVEVVE
                     AQSATTPEEKATSREYAKKGARS"
     gene            26161..29283
                     /gene="mdtB"
                     /locus_tag="RHX21_001897"
     CDS             26161..29283
                     /gene="mdtB"
                     /locus_tag="RHX21_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit MdtB"
                     /protein_id="HDV1987079.1"
                     /translation="MQVLPPSSTGGPSRLFIMRPVATTLLMVAILLAGIIGYRALPVS
                     ALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVITL
                     QFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPM
                     TQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAIT
                     GANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAPIRLGDVATVEQGAE
                     NSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVLSDRTT
                     NIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFS
                     INNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFS
                     LIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCARMLSQESLRKQN
                     RFSRASEKMFDRIIAAYGRGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKGFFPVQD
                     NGIIQGTLQAPQSSSFANMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQ
                     INLKPLDERDDRVQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQLTLQAT
                     SLDALSTWVPQLMEKLQQLPQLSDVSSDWQDKGLVAYVNVDRDSASRLGISMADVDNA
                     LYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKI
                     EQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITTQFQGST
                     LAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALLIAGS
                     ELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPREAIYQACLLRFRPILMTT
                     LAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTK
                     SRFARHEEEA"
     gene            29284..32361
                     /gene="mdtC"
                     /locus_tag="RHX21_001898"
     CDS             29284..32361
                     /gene="mdtC"
                     /locus_tag="RHX21_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit MdtC"
                     /protein_id="HDV1987080.1"
                     /translation="MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPV
                     IMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDIN
                     GAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFAST
                     QLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAISNANVRKPQG
                     ALEDGTHRWQIQTNDELKTAAEYQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTN
                     AKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIAQDRSPTIRSSLEEV
                     EQTLIISVALVILVVFLFLRSGRATIIPAVSVPVSLIGTFAAMYLCGFSLNNLSLMAL
                     TIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLL
                     LMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRLRGFGRML
                     VALQQGYGKSLNWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQA
                     DQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRDERSETAQ
                     QIIDRLRVKLAKEPGANLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRK
                     KLATLPELADVNSDQQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIY
                     QPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGL
                     SAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILI
                     IAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLI
                     GIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSG
                     GDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKPKQTVTE"
     gene            32362..33777
                     /locus_tag="RHX21_001899"
     CDS             32362..33777
                     /locus_tag="RHX21_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1987081.1"
                     /translation="MTDLPDSTRWQLWIVAFGFFMQSLDTTIVNTALPSMAQSLGESP
                     LHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFFTAIVLFTLGSLFCALSGTLNELL
                     LARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTFVTLPGQVGPLLGPALGGLLVEY
                     ASWHWIFLINIPVGIIGAIATLMLMPNYTMQTRRFDLSGFLLLAVGMAVLTLALDGSK
                     GTGLSPLAIAGLVAVGVVALVLYLLHARNNNRALFSLKLFRTRTFSLGLAGSFAGRIG
                     SGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQVVNRFGYRRVLVATT
                     LGLSLVTLLFMTTALLGWYYVLPFVLFLQGMVNSTRFSSMNTLTLKDLPDNLASSGNS
                     LLSMIMQLSMSIGVTIAGLLLGLFGSQHVSVDSGTTQTVFMYTWLSMALIIALPAFIF
                     ARVPNDTHQNVAISRRKRSAQ"
     gene            33774..35177
                     /gene="baeS"
                     /locus_tag="RHX21_001900"
     CDS             33774..35177
                     /gene="baeS"
                     /locus_tag="RHX21_001900"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     BaeS"
                     /protein_id="HDV1987082.1"
                     /translation="MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIK
                     HGNEQRLQLLSDALGEQYAQHGNWRFLRNNDRFVFQILRSFEHDNSEDKPGPGMPPHG
                     WRTQFWVVDQNNKVLVGPRAPIPPDGTRRPILVNGAEVGAVIASPVERLTRNTDINFD
                     KQQRQTSWLIVALATLLAALATFLLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSED
                     ELGKLAQDFNQLASTLEKNQQMRRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPE
                     TVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKAPVDLIPLLEVAGGAFRERFASRG
                     LKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLKISAEQHDKTVRLTFAD
                     SAPGVSDEQLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGG
                     VSITVELPLERDLQREV"
     gene            35174..35896
                     /gene="baeR"
                     /locus_tag="RHX21_001901"
     CDS             35174..35896
                     /gene="baeR"
                     /locus_tag="RHX21_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BaeR"
                     /protein_id="HDV1987083.1"
                     /translation="MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGD
                     QVLPYVRQTPPDLILLDLMLPGTDGLTLCREIRRFSDIPIVMVTAKIEEIDRLLGLEI
                     GADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLD
                     LTPAEFRLLKTLSHEPGKVFSREHLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAE
                     QSFIRAVYGVGYRWEADACRIV"
     gene            36073..36405
                     /locus_tag="RHX21_001902"
     CDS             36073..36405
                     /locus_tag="RHX21_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310915.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HDV1987084.1"
                     /translation="MAGWFELSKSSDNQFRFVLKAGNGETILTSELYTSKASAEKGIA
                     SVRSNSPQEERYEKKTASNGKFYFNLKAANHQIIGSSQMYATAQSRETGIASVKANGT
                     SQTVKDNT"
     gene            36614..36910
                     /locus_tag="RHX21_001903"
     CDS             36614..36910
                     /locus_tag="RHX21_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001307279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system ParD family
                     antitoxin"
                     /protein_id="HDV1987085.1"
                     /translation="MTYTDVRFLLTGGRKMARTMTVDLGDELREFIESLIESGDYRTQ
                     SEVIRESLRLLREKQAESRLQALRDMLAEGLSSGEAQPWEKDAFLRKVKAGIRK"
     gene            36912..37208
                     /locus_tag="RHX21_001904"
     CDS             36912..37208
                     /locus_tag="RHX21_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDV1987086.1"
                     /translation="MRIIKLMPKANEDLEGIWYYSYHHFGEPQADRYVEHLSDVLQIL
                     SNNNIGTPRPELGEGIFVLPFERHVIYFLQSPGEIIVIRILNQNQDATRHLHWS"
     gene            37311..38672
                     /gene="yegQ"
                     /locus_tag="RHX21_001905"
     CDS             37311..38672
                     /gene="yegQ"
                     /locus_tag="RHX21_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-hydroxyuridine modification protein YegQ"
                     /protein_id="HDV1987087.1"
                     /translation="MFKPELLSPAGTLKNMRYAFAYGADAVYAGQPRYSLRVRNNEFN
                     HENLQLGINEAHALGKKFYVVVNIAPHNAKLKTFIRDLKPVVEMGPDALIMSDPGLIM
                     LVREHFPEMPIHLSVQANAVNWATVKFWQQMGLTRVILSRELSLEEIEEIRNQVPDME
                     IEIFVHGALCMAYSGRCLLSGYINKRDPNQGTCTNACRWEYNVQEGKEDDVGNIVHKY
                     EPIPVQNVEPTLGIGAPTDKVFMIEEAQRPGEYMTAFEDEHGTYIMNSKDLRAIAHVE
                     RLTKMGVHSLKIEGRTKSFYYCARTAQVYRKAIDDAAAGKPFDTSLLETLEGLAHRGY
                     TEGFLRRHTHDDYQNYEYGYSVSDRQQFVGEFTGERKGDLAAVAVKNKFSVGDSLELM
                     TPQGNINFTLEHMENAKGEAMPIAPGDGYTVWLPVPQDLELNYALLMRNFSGETTRNP
                     HGK"
     gene            complement(39003..>39276)
                     /locus_tag="RHX21_001906"
     CDS             complement(39003..>39276)
                     /locus_tag="RHX21_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310918.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987088.1"
                     /translation="SGCAVHNDETSIGKFGLAYKSNIQRKLDNQYYTEAEASLARGRI
                     SGAENIVKNDAAHFCVTQGKKMQIVDLKTEGAGLHGVARLTFKCGE"
BASE COUNT         9397 a        10304 c         9825 g         9750 t
ORIGIN      
        1 ctatagccat agctataata gctactcgct tttttcatta cacaattcaa gatacaccct
       61 ttaataacta cgcctgtttg ttcaaagcgt ttaatactta cagcaatttc tttagcagta
      121 tttgcttcaa aacgagctac aagtagagtt gttccagcat atttcccgat tattgccgca
      181 tcggtaacag ccaaaattgg aggcgtatcg acaattacta attcatagtt ctgtgatgcc
      241 caagataata gttccttgaa tcgaggatgc atcagcaact ctgcaggatt aggtggtgtt
      301 tgtccacgac aaatataatc aaaatcaccc tcactgactc tttcgataat actttcaact
      361 ttcgcctggc cagataaaat atcagataaa cctttgacat ttttcgaacc caacattttg
      421 tgaacgtatc cttttcgaag atcagagtcg ataaacagaa ctttctttcc tgtcatcgcg
      481 attgtagcgg ctaaattcgt acttacgaat gttttacccg cattaggact agctccagag
      541 atcattaata tgttattttt cgactccatc attgcaaaat gaagactagt tcttaaactt
      601 ctgatagcct ccacagccaa atctgctggg ttttcaacag ataacaattt atcagactca
      661 tttttttgtc ttttattttt attagtgttt ttagtaagcc attctgatac agggatactc
      721 gcgtatacat tgattcccat ttcttctagc tgctcagggg actcgatacc tctccgcaag
      781 aatactctga cgaacacaaa acctacggaa aagaataacc caatgataat acctaaaaca
      841 atcacaagga tttttttggg tcttaccggt tccggttcag taattgcatt atcaataata
      901 cgtacgttac ctatggcact agatttggca atatttaact cttgctgtcg gctcagcaat
      961 tgtaaataca cagccctacc ggactcaaca tccctgctta atctcaaaac ctcttgttga
     1021 gtcgagggca ttgagctgac tttcttgttt aatttattcc tctccgtttg taatgtttgt
     1081 tttttctcca ttaacgcttt ataagttggg tgttctttcg tatatagctg agaaatctcg
     1141 gcttctctga aagtaagctc attaagttga ttatcaacgt ttactatctg atccaaaaca
     1201 gatttagcct ccattgttaa atcaacagag tctttttgct tacgatagct atttaactta
     1261 tcctcagctg catctaaatc agttcttacc tttggtaatt gttcattcaa aaactcaaga
     1321 ctttttgcat cttgagctgc ttgtcttgca acattttgcg caagatagtt ctgcgtaatg
     1381 ctacttaaaa cttgtgatat taaagtcgga ttatcacctg taaaagtcaa atttaacatc
     1441 ccagtatctt tcccttggtc tgctacattt aatgactcta acaagttgct aatcgctttc
     1501 agacgactta tataggttat tttaaattgg cttccagctt cggcatcgat ggagtctacg
     1561 agaattgaaa ctcccttatc ttccaacaga acaccctttt taccttttaa agaataccct
     1621 tcgcgctcaa tttcaaaatt attctcaccc aagatagtta aagtaacttc agagggtaca
     1681 tcattacttc cactatctaa atagaacctt gagactgata tagtcccggg ctctttaccc
     1741 agcaatcttg ccaaacctcg gccaaatatc gggaaatact ttggctcgat ttctgcttgt
     1801 aaatttagat catctacagt tttccctaat atcattcgag actgaattaa tgctatttca
     1861 ggagctgact gtggttggct atcaggaagc atctgactca gactatctaa aatgacgtta
     1921 ccttgttttt gctcaacctg tattagtgct gttgattgat atattggagt cgctagtaat
     1981 gcatagagca ctgctataac cgtaaaagct gttgtaatag caaaaattag cttgcgatga
     2041 tctattaact caccgacaat tttacctaaa tcgatatcat ccgattcagt aggtgtttgt
     2101 ttgttattcg ttacggatac catgcacttt atcctgatgt tattgaccca tcttttctgc
     2161 ccaactgcgg catgcttgat taattaattg gtatactaaa tcaaatgcct catcactttt
     2221 acggtatgga tcagggattt ctttccctcc catccaatga cctaaaagca ttgttttgcc
     2281 tcttgattca ggagatatat gagtcacttg ctcaagatgg tgcttttcca taaccaatat
     2341 taaatcatat tgacgagcca tagatgacga cagttgttta ccaacatgcc catctaagga
     2401 taaatggtat ttttctgcta cggctattgc cgaagggtca gctgaattcc ctattaaggc
     2461 gccaacacct gctgatgcta tctttttctt tggcatcagt ttttgcagca atctttccgc
     2521 aatcggtgaa cggcaaatgt tccctgtaca aatgactaaa actgaattaa acatctttat
     2581 caccaagtcc ttataaactt accagcttct gtcatatcgt gtacccccgt aatagtcggt
     2641 acgagttgtg aaatcactcg attccaacga accagcggag ctgtagtgac ataaacaata
     2701 tcataaggct gtagttggaa ctctgtggcc aacaccatag ctgatgcatc ttgtgcattt
     2761 aattggtaga tgtttgcaat ctttcctgtt ttatcccctt tcaactgccg gataacaaat
     2821 acacctgtag catcgctcat tgcctgtgaa atcccttctg cattacctaa tgcttcagcc
     2881 aaagtcatac cactacgatc catcttcata gttgcttgtt taactacttc ccccataaca
     2941 aacactttca gatcatcatt acggggtata aataaaatat caccaggata aagaagatgg
     3001 ttttgcgaca aatctccttt ttgcattagc gcatacagtg aaattttcgt atctttaccg
     3061 ttatgtgtta atacaacatt gcgccagtca gcatcaggtg ccagaccacc agcattatta
     3121 attgcatcca tcacagttag tgggatatta gtaatcggct gctggcctga cttcataact
     3181 tcaccagtaa catacgtttt ttgcgatcta aaggcagcaa tactgacatc aacttgaggg
     3241 ctttcgatat atgttgtcaa gcgactggca atatcctggc gtacctgact gattgtttta
     3301 ccagccacct gaactttacc tatatatgga tagaatatcg tgccgtcgga attaacccag
     3361 ttaccagtgt cgctagcgct acggtattgg cctgcaggcg ttgtcaattc gggatgatcc
     3421 caaacagtga ccataagtac atcgccaacc ccgatgcgat attcataact gcgtagtaaa
     3481 ttatccagct gtgggtttgg acgagcaagt acagtctccg gacgaagttg gtcgaccaag
     3541 ctcggggtca tcggatacac attaaccagt ttatcaaggt cgtagtcgct gtcaggaagc
     3601 tccactacgt tcttacgcag aatgtttaat tcctgaccag ggatgattgt acaaccagat
     3661 aaaaaaccaa tcgccaatgc taatgccgaa aatctaacaa gttttttctt cataatgcca
     3721 catcatcagt aaatcaaaat ttgccaattc ctgagcagtt gtcatagccg ttgcttccct
     3781 gccgacttat ggagagaaaa aagctgactg caacctgcag cgctaccacc ttccctcctc
     3841 tgttttcagc attcagcctc ataaactaaa cggtatctct atccctgcgc tggccccaac
     3901 gtcatcgctg tcgctgttgt tagcgttagt gtaccacagg gaggtattca gacgaaccga
     3961 ctgataaaca tcgccgctcc agcccagctg tatacctttt agagtatccg catgagggaa
     4021 tgctttgttg atcgactgat tctccgggtt aaccttcgcg tatactaagc gcgtgctcca
     4081 acgctggtta tcctccgtaa taagctaaac cttaccggca acgagttgac catcaccgcc
     4141 cattgcgtca cccagcggat aacccttctg atagtaacca tccttataga tatgatgcgt
     4201 ataactataa ttggtccggc tcatattgct gcgcgtatca tgcgcttcca ggtaccagtt
     4261 caccgcatcc ttcccccagc tctggtgccc ttcgatcccg ccgaggaaca tatttgccga
     4321 aggcagaaaa cccgactcat cctcgcctat catctgcccg tagaagctca ccggccagcc
     4381 aagagtgggc tcgagtttga acttaaaatc gaacccagcc agttggttac ccggttcatt
     4441 gggatcgttt gcggcggtat tgtctttacc ggttaaccca tcccagaaat tgctgagtga
     4501 ttcagggcgg ccttccccgc cccactgcat aatgcgcgac gcgcctaatt ctaatgactg
     4561 gaaaggtgag aaagtgaaac gaccgccgat aattttggca tgaggtaccg cgatatattg
     4621 attcatctgg ctggcggaga tctggtactg ccatggtccc acccagcgta accaccagat
     4681 ttcaggtgcc gcctgctcgg ctcgctgcat cagaaagcca gtcatcggtc gcatcgcatc
     4741 cccgcggatc aggctacctt catagcccgg tccccaccac tgtagtatct gaccaaaaga
     4801 gagccactgg ttccagaact tcaccgcacc gtaagcaccg ttgacattga agcgcgatcc
     4861 gttgctgatc cgctcccccc cttcgacgtt gccctgcaga tgaacatccc accactcgcc
     4921 gctgttgttg aacgccaagc ctaacgagtt atccgctggc tgtgtctgac caaacccctg
     4981 cggagtgccc ggctggtcgg tcgaagtgta gccggtgcca cggaaatctg cttttaaggc
     5041 agacagtcgc tggttaatac gcgccaagac cacttgttca gaagaatagg atggtttggc
     5101 cttttttagc gcccgggaga tctcttcctg gctcaacggc caagtcgaca ggctcagatg
     5161 gatcaccccg cgatcggaaa gccaggccaa gtcattacgt aagtcgttgt catttaacac
     5221 taacccggcc gcgtaagcct ggggtcccag tgaggaaagc aaacccaacg tcacggcaat
     5281 gcgcgcaatt tttatcattg tacaagatcc attttcagcc ccgttgtcgt atctgaataa
     5341 gaatgatggg aataccaaga tagagagcgc tcgcggcacc agctgacttc gctatgcaac
     5401 accggcgagg caagtacatt taccctaagc tgcttgttag ccttataaca tccactcagc
     5461 tcacaatgta ggcgaatttt accctacagg atatcaatga gacaggaaag ttaatgtcta
     5521 ggcgatatca gcagccgccc ctggccaact tctgaggata tccgtagaaa attgatagat
     5581 atctattggt gatgatcatc ctgaccgggt cgatatttac agccgttgaa gagaatctct
     5641 gtgtagcagc aagcggcttc agcaacgcta ccgcccctgg cttagcagtt accagcgcac
     5701 tgactacctg aacgacttaa ttattcatcg acctgtggat gaataattgg tcaggtcatg
     5761 attttggcgg cgttaagttt acgggatttc ggtcacaatt gggagtgctg ttaccaaata
     5821 tccatcaatt aatgccgcct atcgttctac ttacaaaaaa taagcgggtc atcaattaag
     5881 attattcatt gacttccagg gtcagaaatt ttcccggtac tgttacatca tcatgcatgt
     5941 agctaactta ctgtaaaaaa gggctttttc catagcgtac catctaatta tcagataatt
     6001 gcattatagt caaccactat tcccaatagt ttcctgcatc tagatattca ttgaatgtac
     6061 atcagctaac gtctcagcgc ttttaataaa cgtctgatca aggctatatc caggcaaata
     6121 ttcaataaca atgtagtaac acttcattat ttcataaata tgaattatca attaccggat
     6181 atatagtgga ttattttctt atttgtctaa ttaaccgacg aaaacttaac ttcccctgta
     6241 aaacaaatgg cgattaccag gcatgcaacc ccgccccatg agatattcac gctttccgga
     6301 tgagtggtac gttttgcagc agcagaaaca aagcgctgcc agcggcgcca agcaacaggt
     6361 tagcaatcac ttccgaaaca gaatgcgcat gaatgaccag ccgcgaataa cccaccacag
     6421 cggccacaac atagccggta ataatgaccg ctttacgcag accggaggag aaacgggcgc
     6481 tgagcaacca caggaagata gaccagaagg ccgcagagag cgcggaatgg ctgctaaagc
     6541 cggtgtagtc caactcgcga atccccaggc cccagcccat aaaggccagt ttagaggcgc
     6601 agacgatggc accgattgat accgaacagc aaactccacg gccacgccag caaccgcgac
     6661 gttttacaca gcatcaggac aataaacaac gccgctgagt tgggcagcaa aacggtgcta
     6721 tcgccaaaaa atgagatgag ttgccagttc atatacctgt gatccttcga taatgtccac
     6781 tgccgtgctc agggattatc cgtaatgtct ataccaggtc gcatgccaat tcatttcaca
     6841 tttttatgca tgcaagtgag atgtttaaag cggaaacatg atcgcagtca agttttattt
     6901 ttggctgacg ttgaccgctt tccatgcact ttaggaattg tcgcactaag tgactattca
     6961 taaagcatta ttgccgctac tccgactatt gcaccacaga tgccagagac aaactaccag
     7021 aagtctccga agccatacat ttctttacaa tcgatataac atttacgtta tgaataaatt
     7081 ttgcataacg ttatgagcgg caggacggat gttcagatcc tgtcgctcgg tctcaggctg
     7141 gcgttcaggc cagcagtttt ttaatgcttt cgcggaattt ggcgccctct ttcaggttac
     7201 gcattccgta ggtgacgaag gcctgcatat agcccatttt cttaccgcag tcatagcttt
     7261 cgccagtcat cagcatcgcg tcaacggact gcttcttcgc cagttcggca atggcgtcgg
     7321 tcagctggat acggccccag gcacccggct cggtacgttc cagttcggcc cagatatccg
     7381 ccgacagcac atagcgcccc accgccatca gatcggagtc cagggtctgc ggctcgtccg
     7441 gtttttcaat aaactcaacg atacgcgcca cctggccttc agccaccata ggctctttgg
     7501 tctggatgac ggagtattcg gagagatcgc ccggtatgcg tttcgccagc acctggctgc
     7561 ggccggtttc gttaaagcgg gcgatcaaag ccgcgaggtt atagcgcagc gggtcagcgg
     7621 tgccgccgtc aaggatgata tccggcagga gcaccacaaa cgggttgtcg ccgactaccg
     7681 ggcgggcgca gaggatggaa tgtcccaggc ccaacggctg cgcctgacgc acgttcatga
     7741 tggtcacgcc cggcgggcaa atggcctgca cttccgccag tagctggcgc ttcacgcgct
     7801 gttccagcag ggcttccagc tcataggagg tgtcgaagtg gttttccacc gcgttcttcg
     7861 aggagtgcgt caccagaaca atctctttga tcccggcggc gacgatttcg tcaacgatgt
     7921 actgaatcat tggcttatca acgatcggca gcatctcctt tggaattgcc tttgtggccg
     7981 gcagcatatg catgcctagt cctgcgaccg gaataaccgc tttcaaattc gccatattca
     8041 tcttcacctg tttggttgca aaacacgcgg ttttgcaaaa ttgtacatgt cacaaatcca
     8101 ttgaaactga taatacacgg atactgcccg ggcatatgcc cgccaaattc ttaaattcac
     8161 tgtcacgtaa aagaatacac aaaacgccct tttaccaaca gttagaactg agaataatct
     8221 tattctcgtt caggttattc agcggctcgt tcctttgctc cgcacgatgt ggctgagatg
     8281 cccgtctatc ggggcctgtt ggacgccgga cccgccgcgc gtatgcccga aaagaatata
     8341 tagataataa atttcgccag gcaatatact tcagtataaa cagccggata tgacgtcata
     8401 ttagcctgaa tccgcggcgg tgaactgcga tccgccctat tctgcactca cttcataata
     8461 tgaattatgc cggttttgtg agcgggcttc gcgcttcgct tctgctctgc gcatcagcgc
     8521 tcgccgtgac gaaccgcggg aggaagccct tttgccgccc tcgctgaaac gcagcggata
     8581 aagttctgat atcggcaagc ttattccatg gtcgccgcca tggtgttatt ttttcactgt
     8641 tattttccgg aacataattc ttatcggttc gcttaatccg ctggaaatat atccacccac
     8701 ggcagagcga tgtccgcgtc gttattgcat tttagactaa tcttatccat gatcgtggta
     8761 acacataccg cagtcgtaca ggttttaata catatggaat ggattgccga tccgtcaatc
     8821 tgggtaggtc tcgtcacgct ggtgattatc gaactggtgt tgggtatcga taacctggtc
     8881 tttatcgcta tcctcgccga gaagctccct cccgcccatc gcgaccgcgc gcggatcact
     8941 ggcctgatgc tggcgatggt gatgcgtctc ctgctgctga cctctatctc ctggctggtc
     9001 actctgactc aaccgctgtt cagcttccgc tcgtttacct ttagcgcccg cgacttaatc
     9061 atgctgtttg gtggtttctt cctgttgttc aaagccacaa tagagctgag cgaacggctg
     9121 gaaggaaaag acagcaataa ccccacacaa cgcaaaggtg cgaagttctg gggggtggtg
     9181 acacaaattg tggtactgga cgccatcttc tcactcgact cggtggttac cgccattggg
     9241 atggtcgacc atttactggt catgatggcc gccgtggtta tcgctatcag cctgatgttg
     9301 atggccagca agccgttaac ccagttcgtt aacagtcatc cgacgatcgt tattctctgc
     9361 ttaagcttcc tgttgatgat tggctttagc ctggtggcgg aaggtttcgg cttcgtcatt
     9421 ccgaaaggct atctgtacgc tgccattggt ttctcggtga tgatcgaggt gctcaatcag
     9481 ttggctatct ttaaccggag acgttttctt tccgctaacc agacgctgcg ccagcggact
     9541 accgaagcgg tcatgcgcct gcttagcggg caaaaagaag atgcggaact ggacgccgaa
     9601 accgcgtcca tgctgctgga tcatggtaac cagcagatct ttaatccgca ggaacggcgg
     9661 atgattgagc gggtacttaa tcttaaccag cgtaccgtca gcagcattat gacgtcgcgc
     9721 cacgatattg agcatatcga tctcaacgcg ccggaagaag aaatccgcca gttgctggag
     9781 cgaaatcagc atacgcggct ggtcgttact gatggcgatg acgcagaaga tttgctcggt
     9841 gttgttcacg ttatcgacct gttacaacag tcactgcgcg gcgaaccgct caacctgcgg
     9901 gtgttgattc gccagccgct ggtgttcccg gaaaccttgc cgttgttacc tgccctggag
     9961 cagttccgta atgcccgcac gcactttgct tttgtagtgg atgagtttgg ctcggtggaa
    10021 gggattgtga cattaagtga cgtcactgaa accattgccg gtaacttacc gaacgaagtg
    10081 gaagagatcg acgcccgcca tgatattcag aaaaatgcgg acggttcctg gacggcgaat
    10141 ggtcatatgc cgctggagga tctggtgcaa tatgtgccgc tgccgctgga tgaaaaacgt
    10201 gaatatcaca ccattgccgg actgttgatg gaatatttac agcgtattcc aaaacctggc
    10261 gaagaagttc aggtagggga ttatttgctt aaaacgttgc aggtggaaag ccatcgcgtg
    10321 cagaaggtgc agattatacc gctgcgtgag gatggcgaga tggagtacga ggtgtgataa
    10381 aacatcaaat gcgcaggttc aaactgcgca tttgctttat acaaaattta gtataatcta
    10441 aggatggagt aatgagaaaa aagctggctt ttcttgatac cagtcttgac gatttacgcg
    10501 catttccaga atcgtctcga caggaaattg gctatcaact cggcaggatc caacaaggct
    10561 taaacccata cgactggaaa cctttttcaa ctatcggccc tggtgtgcga gagattcgta
    10621 ctcgcgatgc tgatgggatc tatcgcgtca tgtatgtcgc aaaatttgaa gaagcggttt
    10681 acgtattgca ttgttttcaa aagaaaacac agactaccag tcaatcggat attgatttag
    10741 ccaaacgacg ctataaagaa cttgttcagg agcggaaaaa tgaaaattga aacctttgat
    10801 agtgtgtggg atgcggtgag tgacacccct ggacaagcgg aaaatatgcg gatccgtgcc
    10861 gagcttgtaa cgatcattaa taactggatt gaacaacaag ggtttaacca ggctcaggca
    10921 gcttctgctt taggggtcac tcaacctcgc atatctgaac ttgccagagg taagatccag
    10981 atctttagta tcgataaatt gatcaccatg atggctcatg caggattgca tattcaacgt
    11041 attgaaattc aatatccaca tgctgcttag tgctataaat acagatggcg acaaattgac
    11101 gccgccatct gcataacttg tcttacatct tctccagcaa cttcttcaca tctttgccat
    11161 tgcgggaatc tttattccgc tcggcccagt cgttaagacg gcgtttggct tcgtcctgta
    11221 agtgtttgcg cagtaactga tccacttgca ggctgtaatt gagttgctgc cagttgccat
    11281 aaacccgcag cggtactggc atttctttga ggaaatcaat cagtttgctt tccccgttcc
    11341 aaccgccaat cacacgaatg tcaaactggg tgtcgcaggt ttgatctgcc agattcaaca
    11401 tgccttcccc tgtcagcgcc agcactggcg attgaccttg catgtcgttt aacgtcacga
    11461 cgccatcctt caacgtcaaa tcggtggtaa agcggtcaag acgcgtcacg ttatcaaagt
    11521 tttcagcggc cttcacatca ccaccattac gttctaccgc ttgctgaatc atctgctgga
    11581 agttcatccc ttccatgcgc gtgtcggtca tttcgacatg tgcctgtcct tgccagttat
    11641 ggcggaatgc gtcggcatct atgtcagcac cggagaaatc accagccagt gacatctttc
    11701 cggtcaacga aatcggatag ttaaacgcct tcagaatggt accaatctca acgttttcca
    11761 gccgtggctg gaagtttatc cgcggattta ttgatgtcgc gtccagcgtg cccggcagtg
    11821 aaacctgtcc accgttaagc ttgccctgca gttgagtaat ttccagcaaa cccgacttgt
    11881 tggtcatttg cgtggcaaca tctgtaaaat tcattccgcg ccagcgcacg ttactggcct
    11941 gcaacaaaat atcagccgta aagccttgca gtccctgata ggccggttca tcaatacgcg
    12001 aagaaatgac cgggcgcggc aacgttgatt ggctctgccc ctgctgcgcg gcaccgtttt
    12061 caccgttcgc tgtttcatta agcgggatga ggttgtcaag attcagttgc gggaattgca
    12121 gtctcagctg ccattccggt ttctctgtca acgtgacctg tgcttgcccg ctcagcgtac
    12181 tgtcattagc ggtcaaacta atttggttaa atgaaaggcg tttatgtgac tcctgccact
    12241 gggcctggaa actcccctgc ccctgaatac cttgttttgg taaatctgca ccctgcaact
    12301 gccagttaac ttgttcaata gccgccgtta aatcatgcgg ataatcagaa gcatctaccg
    12361 taccgttaag ggatatcgtg agatcgcgct gatcgcgatt aacccgcccg gagaactcaa
    12421 atgagccacg atgttgggga tcttgttcca tttgcagacg gatattgcgg attgtcacct
    12481 gctcgtcatc ttcatgctgg aacaccagca cgctgtccgc caccttaaga ctggatatat
    12541 caaacgacca tccgcgatcg tctgacagat ccggcaaggt attgtcgcgt ggtgcaaccg
    12601 gggcatcttc actgcgtacc gcttccgtct gcggcgtcag ttggatcact gcccctttta
    12661 gcatcacctg cttaacgctc agttgatgac tcagcagtgg taaaagcgcc acgtccagac
    12721 gcatgttgtc tgcgcgaacc agtggctggc ttgcgccctg ggcggtgaga gacattcgcc
    12781 cggagaggat actaagctgc ggccagacgt gccaacgcag tggcccgtcg agctgcaatt
    12841 gataaccgct acgtgcagca acttgcttga ccatatagtc gcggaaatca ttcggattca
    12901 ccagcaatac taacgcagat aacccgacca ccagcacgac caggagtatc atcagcgtcg
    12961 tcagaaatcg tctcatggta tcctcaatgg gcctgaatta gtctttatcg attcggctgg
    13021 ctaccgcgcc ctgctggttg cgatatttcg catcttcacg gcggttgtaa ggtcgcgccg
    13081 ccgggccgga gagcggctca aagctcagcg caccaattaa catgcccgga cgcagcgcca
    13141 gcggcagctt accggagttg taaaactcca gcacaatgca gccagaccag cccggatcga
    13201 tacggtgcgc ggtgacgtgc accatcagcc ccagacgcgc cagtgaagaa cgcccgtcca
    13261 gccagcccac cagatcggct ggcagcgtca ccgactccag cgtcaccgcc agcgccagct
    13321 ctcctgggtg aagataaaac gcctcgccct cgtcgagcac gatttcatcg ctcatcacgc
    13381 ggtcaagcgc ggcgctcact tcatctttgg gaccgctcag atcgataaac gctgccgtgt
    13441 gaccacggaa ggtacgaaat ttattgccca ggcgcacatc caccgtcgcg ccgttaatac
    13501 gctccactgg cggacgtggg ttgatcgaca aacggccttc atcaagccag gcttcaatat
    13561 ctcggtcaca cagacgcatg gcattttctc ctttcgcgca tcactccctt aacgccaatt
    13621 acgtcaaggg cataccaggt tatcactgaa cggtacacaa tttatcaagc ttattcaaag
    13681 aactgactta ttttcgcttt caatatatcg atggcgatgc ggtttttccc gccgcgcggc
    13741 acgataatgt ccgcatattg tttagaaggc tcaatgaatt gcaggaacat cgggcgcacg
    13801 gttttttgat attgcgccat cactgaatcc attgaacgcc cacgctcgtt aacgtcacgc
    13861 ttgatgcggc gcatcaggca gatatccagc ggggtatcaa cgaaaattga gaagttaagt
    13921 tcgtcacgca aacgcgcatc cgttagcagc aaaatgcctt cgagaatgat gaccttcttc
    13981 ggctcaaccg tcaccgtttc tttcatacgc gtatgttcaa catagctgta aaccggcagg
    14041 tcaattgccg agccgcgttt caacgcttgt aaatgctcaa gcagcaggct gtgatccatc
    14101 gcgctgggat ggtcgtagtt ggtcttaacg cgttcttcca tcgacagatg gctttgatct
    14161 ttgtaatagc agtcttcggg aattacgccg atgtgttcat caccgacttg ctcacgcaat
    14221 tcacgataaa gggtactggc aataagactc ttgccggaag ccgatgcgcc agcgataccg
    14281 ataatgacgc actgatgaga ctgatcagtc atatatttag cgacctgatt aacctggatg
    14341 ttaggaaggg ggcgacgaag cgccaaacgc ggcaattata gggatttcat ccgtctgata
    14401 ccagtcgaat agcgttgccg cgcgctcaga gttaattgtt gacgaagaat tcccggtggc
    14461 aaattacgtt gatcagtttt atacaaggta aaaaatgtta tacgcagttg cgcaaattat
    14521 ccgcctttac gtcactttat gagcaattcg catataaaat gtaaaacttt tgtactagca
    14581 taaacacaga aacgaatact ggcgacctgg tcttgcggat aaagcggtaa tgagcaaaca
    14641 atcacagcat gtattaattg ccctgcccca cccgctgctt cacctggtca gtttaggttt
    14701 agtctcgttt atctttaccc ttttctcgct tgagctttcg cagtttggca cccaactcgc
    14761 cccactgtgg ttcccgacgt ccatcatgat ggtggcgttt tatcgccatg ccgggcgcat
    14821 gtggccggga attgcgctga gctgctcgct gggaaatatc gccgcatcca tcctgctttt
    14881 ttccaccagc tcgctgaaca tgacctggac gaccatcaat attgttgaag ccgtggtcgg
    14941 ggcagtgctg ctacgtaaat tgctgccgtg gtataacccc ttgcaaaatc tggctgactg
    15001 gctgcgtctg gcactcggca gcgccattgt tccgcctctg ttagggggtg ttctggttgt
    15061 cctgctgacg cccggagacg atcctctcag ggcatttttg atatgggtac tgtcagaatc
    15121 catcggcgct ctggcactgg tgccgctggg attgttattt aaaccacact atctgctgcg
    15181 ccatcgcaac ccacggttgc tttttgagtc gctgctcacg ttagccatca cactgacgtt
    15241 aagctggctt tcgatgctgt atctgccgtg gccttttact ttcattattg tgctgttgat
    15301 gtggagcgcc gtgcgcctgc cacgaatgga agcctttttg atcttcctta ccacggtgat
    15361 gatggtgtca ctgatgatgg ccgcggatcc ctccctgctt gctacgccgc gtacatacct
    15421 gatgagccat atgccgtggc taccgttttt gctgatcctg ctgcccgcca acatcatgac
    15481 catggtgatg tatgcctttc gtgcggaacg caaacacatt tccgaaagcg aaacccgctt
    15541 tcggaacgcg atggaatatt ccgccatcgg catggcatta gtgggcaccg aggggcaatg
    15601 gctgcaatcc aacaaagcgc tctgccagtt tctcggttac agtcaggaag aactgcgcgg
    15661 actcaccttt cagcaactga cctggccgga ggatctcaat aaagatctgc aacaggttga
    15721 aaagctgatc agcggtgaaa taaacaccta ttcaatggaa aaacgctact acaaccgcaa
    15781 tggcgatgtt gtctgggcgt tgcttgccgt ctcactggtg cgccacaccg atggtacgcc
    15841 gctctatttt atcgctcaga ttgaagacat taacgagcta aaacgcaccg aacaggtgaa
    15901 tcagcaactg atggagcgca tcacgctggc taacgaagcg ggcgggattg gcatctggga
    15961 gtgggtgctt aagccgaata tttatagctg ggataagcgg atgttcgagc tgtatgaaat
    16021 tcctccgcat atcaaaccga actggcaggt gtggtacgag tgcgtgctgc cggaagatcg
    16081 ccagcacgcc gaaaaagtga ttcgcgattc attgcaatcg cgctctccct ttaaactgga
    16141 atttcgcatt gccgtgaaag atggcatccg ccatatccgc gccctcgcca accgggaact
    16201 gaataaagaa ggcgaagtcg aacgtctgct cggcattaat atagatatga ccgaggttaa
    16261 acagcttaac gaggcattgt ttcaggaaaa agagcgcctg cacattacgc ttgattccat
    16321 cggtgaagcc gtggtctgta ttgatatggc gatgaaaatt acctttatga atccggtggc
    16381 ggagaagatg agcggctgga cgcaggaaga agcgttaggt gttccactcc tgacggtgtt
    16441 gcatattact tttggcgaca acggaccatt aatggagaac atttacagtg ccgacacctc
    16501 acgttccgcg attgaacaag atgtggtgtt gcactgccga agcggcggca gctacgacgt
    16561 gcattacagt attacgccgt taagtactct ggacggcagc aatattggtt cggttctggt
    16621 gattcaggac gtcaccgaat cgcgcaaaat gctgcgccag ctgagctaca gcgcctccca
    16681 tgatgcactg acgcatctcg ccaatctcgc cagttttgag aagcaactac gcatcctgct
    16741 gcaaacggta aacagtacac atcagcgaca tgcactggtg tttatcgatc ttgatcgctt
    16801 taaagcggtg aatgacagcg ccgggcacgc cgctggcgac gctttgttgc gcgaactggc
    16861 gtcattgatg ctgagtatgc tgcgctccag cgacgtgctg gcgcgactcg gtggcgatga
    16921 atttggtctg ctgctgccag attgtaatgt cgaaagtgcg cgttttatcg ctacacgcat
    16981 tatcagcgcc gtaaatgact atcactttat ctgggaagga cgtgtacatc gggtaggtgc
    17041 cagtgccggg attaccttga ttgatgacaa caatcatcag gcggctgaag tgatgtcgca
    17101 ggctgatatc gcctgttatg cctccaaaaa tggtggacgg ggccgggtga cggtttacga
    17161 accgcagcaa gctgccgcac atagcgaacg ggcggtgatg tcgcttgatg aacagtggcg
    17221 gatgattaaa gagaatcagt tgatgatgat cgcccacggt atcgcttcgc cgcggatccc
    17281 gcaagcgcgt aatttgtggc tgatttcact taagctctgg agttgcgaag gcgagattat
    17341 tgatgaacaa acatttcgtc gtagcttcag cgatccggca cttagccatg ctcttgaccg
    17401 acgggtattc cacgattttt tccagcaggc cgcaaaagcg gttaccagta aaggcttaag
    17461 catcgccctc cccctttccg ttgccggttt gagtagcacc acactggtaa atgaactgct
    17521 tgaacagctg gaaaacagcc ctttaccacc acggttatta catctgatta ttccggcaga
    17581 cgcgatttta gatcacgcag aaagcgtgca aaaactgcgg ctggcgggat gtcggatcgt
    17641 attcagtcag gtgggccgcg atctgcaaat cttcaactcg ctgaaagtaa atatggcaga
    17701 ttacctacta cttgatggtg agttatgcgc caacgtgcag ggaaatttga tggatgagat
    17761 gctgattacg atcattcagg ggcacgctca gcggctcggg atgaagacca tcgccgggcc
    17821 agtagtttta cccctggtga tggatacgct ttctggcatc ggcgtcgatt tgatttatgg
    17881 tgatgtgatt gccgatgccc aaccgctgga tttgctggtg aatagcagtt atttcgcgat
    17941 taactaaggc gtgcttcccc atcgcctgat gcggcgtatc aggcctacaa ttcgtccgtt
    18001 ccgtctggtt gccagccttc cgtataccag atatgcaaca gcgcataaga acgccagggc
    18061 ttccagcgtt cggcataacg gcggatttgt gccggtgtca ttcccggaaa tcgctgttta
    18121 atcagataat catccggcag gaaaacatct ttcacctgcc agccgcgcaa ggcgaaataa
    18181 ttcgccgtcc agcgcccgat acccggaaaa gtttgcagcg ttttcatcgc ctgctccaca
    18241 tcgcccggta ttgtcattgg taaggtgccc tccagcgccg catttgccag atgaatcagc
    18301 gcctctgccc gtttcaacgg catacctaac gcttttaatg cctgcggatc tgctgctgcc
    18361 agccgctgag gcgtggggaa gcagacataa tccggaaaat catccagccg ttcgccataa
    18421 agctgtgcca ctctggcggt caattttgcc gccatcgcca cgctcaccag ttggcctaaa
    18481 atcgcccgca cgccctgctc agaagcatca acactgccgg gtaaacgcaa tccgggccgc
    18541 gccgcgccta acttgcccaa cgcaccgtta acaatctgcg ggttacattg cagatcaaac
    18601 aggcggctca ttttcgccag acactctgcg gcaacaggtt ctaaacctgc acttaaattt
    18661 atgtgcagag tatggcgggc tatatccgga atagcagtca ccacgccgcg atattcgccc
    18721 accgccagac tacgggcata ataatcgtca gcgaccgttt ccacaccgtt caccgcacgg
    18781 gcggcgagaa atcccaacat ccacgaccag tcatatggcg gctgccagtt cagggtatac
    18841 atcgcatctc cttgttaatc cgctttcagc ataaacgtta ttcagacgct acgctttgct
    18901 ttcatattcc ggttgtcgcg acggcaacat ttcgctaaag tcacgcccct tcttcaccgg
    18961 catggggatt atttcgtgtt tattggtttt gattacggta cagcaaactg ttcagtggcg
    19021 gtcatgcgcg acggtaagcc gcaattactg aaaatggaaa acgacagcac gctgctgcct
    19081 tcaatgcttt gcgcgccaac gcgtgaagcg gtaagcgaat ggctgtaccg ccatcatgat
    19141 gttccggcag acgacgatga aacgcaggcg ctgttgcgtc gggcgattcg ttataaccgc
    19201 gaagaagata tcgatgttac ggcgaaaagc gtgcagttcg gtctttcctc actggcacag
    19261 tacattgatg atccagaaga ggtgtggttt gtgaaatcac caaaatcatt cctcggtgcc
    19321 agcggcttaa aaccgcagca ggtagcgctg tttgaggatc tggtctgcgc aatgatgttg
    19381 cacattcgcc agcaggcgca ggcgcagctg ccggatgcga ttactcaggc ggtgattggt
    19441 cgcccgatca acttccaggg gctgggcggc gatgaagcaa acacccaggc gcaagggatt
    19501 ctggaacgcg cggcaaagcg tgccgggttt aaggatgtgg tattccagta cgagccggtc
    19561 gcggctgggc tggattacga agccaccttg caggaagaaa aacgggtgct ggtggtggat
    19621 atcggcggtg gtacgactga ctgttcattg ctgctgatgg ggccgcagtg gcgttcgcgt
    19681 ctcgatcgtg aagccagcct gctgggtcac agtggttgcc gtattggcgg taacgatctg
    19741 gatatcgcgc tggcgtttaa aaacctgatg ccgttactgg gcatgggtgg cgaaaccgaa
    19801 aaaggcatcg ccctgccgat tctgccgtgg tggaatgcgg ttgccatcaa cgacgtacct
    19861 gcgcaaagtg atttctacag tagtgccaac ggtcgtctgc ttaacgatct ggtacgcgat
    19921 gcccgcgaac cggaaaaagt ggccctgtta cagaaagtct ggcgtcagcg tttaagctat
    19981 cgcctggtac gtagcgcaga agagagcaaa attgcgcttt caagcgtagc ggaaacccgc
    20041 gcctcactgc cgtttatcag cgatgaactg gctacgctga ttagccagca agggctggaa
    20101 agcgccctca accagccact ggcgcggatt ctggaacagg tgcaactggc gctggataac
    20161 gcccaggaaa aaccggatgt tatctatctg accggcggta gcgcccgttc accgctgatt
    20221 aaaaaagcgc tgacagaaca gttgccgggc attccgattg caggtggcga tgactttggc
    20281 tccgtcaccg ccgggctggc acgctgggcg gaagtggtgt ttcgttaatt gaaaactggc
    20341 tcagcaacgg cttaaatcag cctgcgcctg agccagtttt tctgccgcct gacgtagcgg
    20401 ttccatcaac ggcatggtcc gtgctggagc atgaaggcgg aatcgctgca actctgtcgc
    20461 accgacagtc agcgccgatt ccagccgatg tcgtttggcg gccatttttg ccattaccgc
    20521 ttgtctgtct gcaggcgtta ccgcttcgtt cggcctgaaa acaaaacggc gttcgcaact
    20581 cgctttccag tcgataaccg cctgggtcag atgatcacca aaacctttta cttgcttaac
    20641 gctccgtcgg gtaacgtctg cggcggtttc aataccaaaa gaccgtaacg ccgctttacg
    20701 cgctgggcct acgccgggaa tagaggcagc atcgataaaa aatccctcca gaaacttctg
    20761 cttctgccgt tcccttgcgt tgtcctgaag tgctgccaga gcgcgtttct cctcttccgg
    20821 taacccaaga atttcgtcct tcattttttc gagcatcgtc cgtttggcga taaaaccttc
    20881 cagcccgccc aactgttgga tctggctgac taaatggtca tagtccattt ttgcgcgatt
    20941 aaaagcctct cttcgtcgct ggacttctgc tttgtacgct ttgcttgtaa ggctgccaat
    21001 aatccagata gccgccagca cgggaaccaa aatgatataa cgcggttcta cctgaaggcc
    21061 gcaaagcagc agcgataacg ctgacagtgc gatctcaatc agaatgatgt attcacgccg
    21121 taacaggcct aaaggaagcg gcctgccagt cggttggaaa tgatcgggta atggcaattg
    21181 caatgctggc ggtgctactg acgccatcac catcgcccag actttcgcca gcacaaaatc
    21241 accgctggtg gtaatgacct cttcgccgag atcaataaaa tagataacgc cttgattatc
    21301 cagcgcacac cacgggcagt cggtcaaatg accggggtaa atatgcattg ccgaaacggt
    21361 acatttcttt aactgttggc gtagtaaatc aagtgccgct acccacgctt ttgccgtcgg
    21421 acgcccggtt gccacgccac tttccgtgaa tgcctgctga aacatggctt caacatcacc
    21481 cggtaacatc gacagcggaa tagatcgtgg cggcggtgtt aaaccacgtc gctgattatc
    21541 tgacgcgtag gcataacgga aatgggcaat atccgtctcc agtgcattcc ccgcatcaga
    21601 gataagcggc acaccagaat aaggatgccg cccaccaaac aagacgtgaa aaatcagcaa
    21661 cgcaaggcca aaattatcgt gattttctgt gcgttcaaag ccgataaatg acgacaaggt
    21721 ttgtagctct ggcggcgtaa aatacgacac gccgacttcg cataaatgca gcgtgccatt
    21781 ggcgttaatc tgaaaggagt cgctatcaat caacaccact ttgctgtcgc gacctaccat
    21841 aaagctgttc tggtttacgt cacccacgac gtgcccgtgc tcgtgaatcg tagcaaaaga
    21901 tgaagcaata ttgcgcgcaa catagagtag aaaatcccac gcacagtgag ggtaactctg
    21961 gcgacgatgt gccgcgggct atagatcata tgaatcggtt ctttaccaga aacttttggc
    22021 atcataaaac cgataacctt tccgcctcgt ccaccgtgaa gcgttgcctg cggccaggcg
    22081 acataattca acaattgcgc gtcagctgtc gcagccataa aggcaagttt gtcctgtttt
    22141 aaggcgggtg gcggcgtgtg ataaatcttg gcgacgctat cgacaaactc ctcgatatca
    22201 taaaccgcac cttcgccgcc tttgcccagt tcacggccag gcgtaacgca ctcaccagta
    22261 gcagtatata aagtgggttt catggtaacc acagcgccag tgccaacgtt ttatcatcat
    22321 cggtacgctc gtttaccgcc gggctggaca aaaactgctt taacaattca ggtaataaat
    22381 cgagttgttc ctgcgttgct gacgccagtc cattgaaaaa cggggtaaag aaaggcacat
    22441 gcggagaatt atccagcata tttaacgcca gtcgctgaat accatccgta aatgctgcaa
    22501 ctttatgcgc acgctcagta ctggtgtaag tttccagtct ggaaacagca tcgtcatcgg
    22561 taatgaagtg cgtcatattg gcatattccc ccaccatcgg cgtgagcggc agttgcaaac
    22621 cgtgacccaa atctaccacc acgccgccat cgccaatctg cataatcaag gtgccattag
    22681 ctgatgaaat caatcccaaa aacgtgcagg caaaatcgcg aaccgctaat tctttggctt
    22741 ccgcctcggc aaaaagtcgc tgacgaatgg tcagcacaat gtccgttgcg aggacatcat
    22801 taagccccaa ttccccgccc tgcacttttt gcgacatata agccatcgct tcattgacgg
    22861 cgagcatcgc accttcgcca ccctgcgaga cgctgcctgc gccatcagcg acaaataccg
    22921 acaataatgg ctgctggtct tctaaccagg caacctgcat ctggcaggca tcctggcaag
    22981 acaagtcagc gctgatgtgc gacgttccaa cggctgatgc ataaaccaga cgccagctca
    23041 cactgacgtc cagccttttg gcgcttccag cacaacttcc gttcccggcg tggagcggga
    23101 aaccgaacgc agcgaactgg ataaccagct aaacagttcg cggaattgta atccttgaag
    23161 aggcaaaggc tgacgaacgc tgatttgggc cagcgtcttc atatccgccc cctgaacacc
    23221 gatggaaaag aaggcaaact tcttatcttc ttccccctga aacaccttgt tggcagcagc
    23281 ctgccactca tcggttggtg cgccatcggt aatcaggaaa atccacggac gataatagga
    23341 aataccattg gcgcgatact cacgtttgcg ctcctcaacc atattcaggg ctttggtaat
    23401 ggcggcgccc attggtgtat ccccatgggc aaacaggatg ggcgggaaaa aattagcggc
    23461 actggtaaat ggttgttcca catgcaccgg gccgaacgtc acaataccga gttccactct
    23521 ttttaaggcc agcgaatcgg caagcagctc atcgcgaaag gtaaccaatc cggcgttaag
    23581 ttcattaata ggtctaccgt tcatagaacc agaaacatcc agcagcaaaa tgcaggggca
    23641 acgtggttcc gggttactgg caaaatcgct ggtggcaaac gtgatttgtt cgctcataag
    23701 aaatcctttc ttagagaatt attgaggtcc ggtatcatac cgattgcaat aatgaaataa
    23761 gagcaaacga agaaactttc agaattaggc ccggcggcgc agaaaatttt gctattcgcc
    23821 tcgcaagaac ggagagccgt cgattgacac taagggcgga gtgacataat ttcaggagtg
    23881 agggttaggg agaggtttcc cccctccccc tggtgttctt agtaagcctg gaagctaatc
    23941 actaagagta tcaccagtat gatgacgtgc ttcatcataa ccctttcctt attaaaagcc
    24001 ctcttctccg ggagagggtt tcccgtttca gcgtcccgct gaaatcgtcg gcttacctcc
    24061 tttcgccctg aatgcagtct atcgctaacg cgtgaacaaa atagtttcct ctgtgattat
    24121 tgcgtaacga ctcgcaaaga atatttgctg gcaggatcgc agactacaaa gcctgcggat
    24181 tgacaatctt atcgtgaagg cataatttca ggagtgaggg tagagcgggg tttcccccgc
    24241 cctggtagtc ttagtaagct ggccagctaa taactaagag caccacgatg atgagtagct
    24301 tcatcatgac cctttcctta tttaaggccc cttcctcggg aggggctttc ccgtttcagc
    24361 gtcccgctga aatcgtcggc ttacctcctt tcgccatgca cttagtctat cgctgacttg
    24421 cagataaaat agtttccagt gtgattattg cgtaacgtct cgcaaagaat ttttgctggc
    24481 aggatcgcag acggcaaagc ctgcggattg acaatcttat cgtgaaggca tactttcagg
    24541 agtgagggta gagcggggtt tcccccgccc tggtagtctt agtatgctgg gtagctaatc
    24601 actaagagca ccacgatgat gagtagcttc atcatgaccc tttccttatt taaggcccct
    24661 tcctcgggag gggctttccc gtttcagcat ccggctgaaa tctgcggctt acctcctttc
    24721 gccctgtatg cagtctatcg ctaacgcgta gataaaatag tttcctgtgt tattactgga
    24781 tgcgtgctcg caaatgtgcc cgccattcag acgattcccg atagtgtttc ataattcctc
    24841 catttttctc ccttattggc tggctacact agtatcattc cgcgaaacgt ttcaggaaga
    24901 gaaactctta acgatgaaag gcagttataa atcccgttgg gtaatcgtaa tcgtggtggt
    24961 tatcgccgcc atcgccgcat tctggttctg gcaaggccgc aatgactccc agagtgcagc
    25021 cccaggggcg acgaaacaag cgcagcaatc gccagcgggt ggtcgccgtg gtatgcgttc
    25081 cggcccatta gccccggttc aggcggcgac cgccgtagaa caggcagttc cgcgttacct
    25141 caccgggctt ggcaccatta ccgccgctaa tactgttacg gtgcgcagcc gcgtggacgg
    25201 tcaactgatg gcgttacatt tccaggaagg ccagcaggtc aaagcaggcg atttactggc
    25261 agaaattgac cccagccagt tcaaagttgc attagcacaa gcccagggcc aactggcaaa
    25321 agataaagcc acgcttgcta acgcccgccg tgatctggcg cgttatcagc aactggcaaa
    25381 aaccaatctc gtctcccgtc aggagctgga tgcccaacag gcgctggtca gtgaaaccga
    25441 aggcaccatt aaggctgatg aagcaagcgt cgccagcgcg cagctgcaac tcgactggag
    25501 ccgcatcacc gcaccagtcg atggtcgcgt tggtctcaag caggttgatg ttggtaacca
    25561 aatctccagt ggtgatacca ccggaattgt ggtgatcacc cagacgcatc ctatcgattt
    25621 agtctttacc ctgccggaaa gcgatatcgc tactgtagtg caggcgcaaa aagccggaaa
    25681 accgctggtg gtagaagcct gggatcgcac caattcgaag aaattaagtg aaggcacgct
    25741 gttaagcctc gataaccaaa tcgatgccac aaccggtacg attaaagtga aagcacgctt
    25801 taataatcag gatgatgcgc tgtttcccaa tcagtttgtt aacgcgcgca tgttagtcga
    25861 caccgaacaa aacgccgtag tgatcccaac agccgccctg caaatgggca atgaaggcca
    25921 ttttgtctgg gtgctgaata gcgaaaacaa ggtcagcaaa catctggtga cgccgggcat
    25981 tcaggacagt cagaaagtgg tgatccgtgc aggtatttct gcgggcgatc gcgtggtgac
    26041 agacggcatt gatcgcctga ccgaaggggc gaaagtggaa gtggtggaag cccagagcgc
    26101 caccactccg gaagagaaag ccaccagccg cgaatacgcg aaaaaaggag cacgctcctg
    26161 atgcaggtgt tacccccgag cagcacaggc ggcccgtcgc gcctttttat tatgcgtcct
    26221 gtcgccacca cgctgctgat ggtggcgatc ttactcgccg ggattatcgg ttatcgcgcc
    26281 ctgcccgttt cggcgctgcc ggaagtggac tatccgacca ttcaggtggt cacgctctac
    26341 ccaggtgcca gcccggatgt catgacctct gccgttaccg cgccgctaga acgccagttc
    26401 gggcagatgt ctggcctgaa acagatgtcg tcgcaaagtt ccggcggtgc gtcagttatc
    26461 actttgcagt tccagctaac attaccgctc gatgtcgccg agcaggaagt gcaggccgcg
    26521 attaacgctg cgaccaactt gttgccgagc gatctgccta acccgccggt ttacagcaaa
    26581 gtgaacccgg cagatccgcc gatcatgacg ctcgccgtca cctcaaccgc catgccgatg
    26641 acgcaagtgg aagatatggt ggaaacccgc gtcgcgcaga aaatctcgca gatttccggt
    26701 gtcggactgg tgacgctttc cggcggtcag cgtccggctg ttcgcgtcaa acttaacgct
    26761 caggcgattg ccgccctcgg cctgaccagc gaaaccgtgc gcaccgccat taccggcgct
    26821 aacgttaact cggcaaaagg tagcctcgac ggcccttccc gtgcggttac gctttccgct
    26881 aacgaccaga tgcaatccgc cgaagagtat cgccagctaa tcatcgccta ccagaacggc
    26941 gcgccaattc gtctgggcga tgtcgcaact gtagagcaag gtgcagaaaa cagctggctc
    27001 ggcgcgtggg cgaacaaaga acaggccatt gtgatgaatg ttcagcgcca gcccggtgct
    27061 aacattatct ccaccgccga cagcattcgg cagatgctgc cacagctcac tgagagtctg
    27121 ccgaaatcgg tgaaggtgac agtgctttcc gatcgcacca ccaatatccg cgcatccgtc
    27181 gatgatactc agtttgaatt gatgatggct atcgcgctgg tagtcatgat tatctacctg
    27241 tttttgcgca atattccggc gaccatcatt cccggtgttg ctgtaccgct gtcgttaatc
    27301 ggcactttcg cggttatggt gtttctcgat ttttcaatca ataacctgac actgatggcg
    27361 ttaactatcg ccaccggatt cgtggtcgat gacgccatcg tggtgatcga aaacatttcc
    27421 cgctatatcg aaaaaggcga aaaaccgttg gcggcggcgc tcaagggcgc aggtgaaatc
    27481 ggctttacca ttatctcgct gaccttctca ctgattgcgg tgttgatccc actgctgttt
    27541 atgggcgata tcgtcgggcg actgttccgc gaatttgcta ttaccctggc ggtagcgatt
    27601 ttgatctcag cggtggtgtc gctgaccctg acaccgatga tgtgcgcgcg gatgctcagc
    27661 caggagtcgt tgcgtaaaca gaaccgcttc tcccgtgcct cggaaaaaat gttcgacagg
    27721 ataatcgccg cctatggtcg tggactggcg aaagtgctga atcatccgtg gctgacctta
    27781 agcgtggcac tcagcacgct gctgcttagc gtgctgctgt gggtgttcat tccgaaaggt
    27841 ttcttcccgg tacaggacaa tggcattatt cagggcactt tgcaggcacc gcaatccagc
    27901 tcctttgcca atatggccca gcgacaacgc caggtcgcgg acgtgatttt gcaggatccg
    27961 gcagtgcaaa gcctgacctc atttgttggc gttgatggca ctaacccgtc gctgaacagt
    28021 gcacgtttac aaatcaacct caaaccgttg gatgaacgtg atgatcgggt gcaaaaagtc
    28081 atcgcccgtc tgcaaacggc ggtagataaa gtgccgggcg tcgatctctt cctgcaacca
    28141 acgcaggatc tgactattga tactcaggtc agccgcaccc agtaccagtt aaccttgcag
    28201 gccacgtcac tggatgcgct cagtacctgg gtgccacagt tgatggaaaa actccagcaa
    28261 ctgccacagc tttctgatgt ctccagcgac tggcaggaca aagggctggt ggcgtatgtc
    28321 aatgttgatc gcgacagcgc cagccgtctg gggatcagca tggcggatgt cgataacgcc
    28381 ctgtacaacg cgtttggtca gcggctgatt tccactattt atactcaggc caaccagtat
    28441 cgcgtggtgc tggagcacaa caccgaaaat accccaggcc tcgcggcgct ggataccatt
    28501 cgcctgacca gcagcgacgg cggcgtggtg ccgctaagct caattgccaa aattgagcag
    28561 cgttttgcgc cgctctccat caaccatctg gatcagttcc cggtaacgac catctccttt
    28621 aacgtgccgg ataactattc gctgggcgat gcggtgcagg cgattatgga caccgaaaag
    28681 acgctgaatc tgccggtgga tatcaccacg cagttccagg gcagcaccct cgccttccag
    28741 tcggcgctgg gcagcactgt ctggctgatt gtcgcggcgg tggtggcgat gtatatcgtg
    28801 ctcggcattc tgtacgagag ctttattcac ccgatcacca ttctctcgac gctacccacc
    28861 gcaggggttg gcgcactgct ggcgttgctg attgctggta gcgaactgga tgtgattgcg
    28921 attatcggca ttattttgct gatcggtatc gtgaagaaga acgccatcat gatgatcgac
    28981 ttcgcgctgg ctgccgagcg cgagcaaggc atgtcgccgc gcgaggcaat ctaccaggct
    29041 tgtctgttgc gttttcgtcc gatcctgatg accactctgg cggctctgct tggcgcgctg
    29101 ccgctgatgt tgagtaccgg ggtcggcgcg gaactgcgtc gtccgttagg tatcggcatg
    29161 gtcggcggtc tgattgtcag ccaggtgctg acgctgttta ccacgccggt gatttatttg
    29221 ctgttcgacc gcctggcatt gtggaccaaa agccgctttg cccgtcatga agaggaggcg
    29281 taagtgaagt tttttgccct cttcatttac cgcccggtgg cgacgatttt actgtcggtt
    29341 gccattaccc tgtgcggcat actgggcttc cgtatgctgc cggtcgcccc gctgccgcag
    29401 gtcgattttc cggtgattat ggtcagcgcc tcgctgcccg gtgcgtcacc agaaacaatg
    29461 gcgtcttccg ttgccacgcc gctggagcgc tcacttgggc gcattgccgg agtcagtgaa
    29521 atgacctcca gcagttcgct cggcagcacg cgtattattt tgcagtttga ttttgaccgg
    29581 gatatcaacg gcgcggcgcg cgatgtgcag gcggcgatca acgctgcaca aagtttgctg
    29641 cccagcggga tgcccagccg tccgacctat cgcaaagcta acccgtcgga tgcgccaatt
    29701 atgatcctca cgctgacatc cgatacttat tcgcagggtg aactgtacga ttttgcctcg
    29761 acgcagctgg ctccgacgat ttcgcaaatc gacggtgttg gtgatgtcga tgtcggcggc
    29821 agctcactgc ccgccgtacg cgtcgggctg aatccgcagg cgctgtttaa tcagggcgtc
    29881 tcgctggacg acgtacgcac tgccatcagc aatgccaacg tgcgtaaacc gcagggggcg
    29941 ctggaagatg gcactcaccg ctggcagatc cagaccaatg atgagctaaa aaccgccgcc
    30001 gaatatcagc cgctgattat tcattacaac aacggcggcg cggttcgtct gggcgatgtg
    30061 gcgacagtga ccgactctgt acaggatgta cgtaacgccg ggatgaccaa tgccaaaccg
    30121 gctattttgc tgatgatccg caagctgccg gaagccaata ttatccagac ggttgacagc
    30181 atccgggcaa aattaccgga gttgcaggaa accattccgg cggcgattga tctgcaaatt
    30241 gcccaggatc gctcccccac cattcgctcc tcgctggaag aagtcgagca aacgctgatt
    30301 atctcggtgg cgctggtgat tctggtggtg tttttattcc tgcgctcggg tcgcgccact
    30361 attattcccg ccgtttcggt gccggtttcg ctgattggta cgtttgcggc gatgtacctg
    30421 tgcggattca gtctcaataa cctttcgtta atggcgctca ccatcgctac tggtttcgtg
    30481 gtggatgacg ccatcgtggt gctggaaaac attgcccgtc atctggaagc gggaatgaaa
    30541 ccgttgcaag ccgcactgca aggtactcgc gaagtcggtt ttacggtgct gtcgatgagt
    30601 ctgtcactgg tggcggtgtt cctgccgctg ctgttgatgg gcggattgcc gggccgactg
    30661 ttacgcgagt ttgccgtgac gctttctgtc gccattggta tttcgttgct ggtttctctg
    30721 acattaacgc caatgatgtg tggctggatg ctgaaagcca gcaagccgcg cgagcaaaag
    30781 cgactgcgtg gttttggtcg catgttggta gccctgcaac aaggctacgg caagtcactg
    30841 aactgggtgc tcaatcatac ccgtctggtg ggcgtggtgc tgcttggcac cattgcgctg
    30901 aatatctggc tgtatatctc gatcccgaaa accttcttcc cggagcagga cactggcgtg
    30961 ctgatgggcg ggattcaggc ggatcagagt atttcgtttc aggcgatgcg cggtaagttg
    31021 caggatttca tgaaaattat ccgtgacgat ccggcagtgg ataatgtcac cggctttaca
    31081 ggcggttcgc gagtgaacag cgggatgatg tttatcaccc tcaagccacg cgacgaacgc
    31141 agcgaaacgg cgcagcaaat tatcgaccgt ctgcgcgtaa aactggcgaa agaaccgggg
    31201 gcgaatctgt tcctgatggc ggtacaggat attcgcgttg gtgggcgtca gtcgaacgcc
    31261 agctaccagt acacgttgtt atccgacgac ctggcggcac tgcgcgaatg ggagccgaaa
    31321 atccgcaaaa aactggcgac gttgccggaa ctggcggacg tgaactccga tcagcaggat
    31381 aacggcgcgg agatgaatct ggtttacgac cgcgacacca tggcacggct gggaatcgac
    31441 gtacaagccg ccaacagtct gttaaataac gccttcggtc agcggcaaat ctcgaccatt
    31501 taccagccga tgaaccagta taaagtggtg atggaagtgg atccgcgcta tacccaggac
    31561 atcagtgcgc tggaaaaaat gttcgttatc aataacgaag gcaaagcgat cccgctgtcg
    31621 tatttcgcta aatggcaacc ggcgaatgcc ccactatcgg tgaatcatca gggattatcg
    31681 gcggcctcga ccatttcgtt caacctgccg accggaaaat cgctctcgga cgccagtgcg
    31741 gcgatcgatc gcgcaatgac ccagcttggt gtgccttcga cggtgcgcgg cagttttgcc
    31801 ggaacagcgc aggtgttcca ggagacgatg aactcacagg tgatcctgat tatcgccgcc
    31861 atcgccacgg tgtatatcgt gctgggtatc ctttacgaga gttatgtgca cccgctgacg
    31921 attctctcca ccctgccctc ggcgggtgtt ggagcgctgc tggcgctgga gctgttcaat
    31981 gccccgttca gcctaatcgc cctgataggg atcatgctat taatcggcat cgtgaagaaa
    32041 aacgccatta tgatggtcga ttttgcgctt gaagcccaac ggcacggtaa cctgacgccg
    32101 caggaagcta ttttccaggc ctgtctgctg cgttttcgcc cgattatgat gactaccctg
    32161 gcggcgctgt ttggcgcgct gccgctggtg ttgtcgggcg gcgacggctc ggagctgcgg
    32221 caacccctgg ggatcaccat tgtcggcgga ctggtaatga gccagctcct tacgctgtat
    32281 accacgccgg tggtgtatct ctttttcgac cgtctgcggc tgcgtttttc gcgtaaacct
    32341 aaacaaacgg taaccgagta aatgacagat cttcccgaca gcacccgttg gcaattgtgg
    32401 attgtggctt tcggcttctt tatgcagtcg ctggacacca ccatcgtaaa caccgccctt
    32461 ccctcaatgg cgcaaagcct cggggaaagt ccgttgcata tgcacatggt cattgtctct
    32521 tatgtgctga ccgtggcggt gatgctgccc gccagcggct ggctggcgga caaagtcggc
    32581 gtgcgcaata ttttctttac cgccatcgtg ctgtttactc tcggttcact gttttgcgcg
    32641 ctttccggca cgctgaacga actgttgctg gcacgcgcgt tacagggcgt tggcggcgcg
    32701 atgatggtgc cggtcggcag attgacggtg atgaaaatcg taccgcgcga gcaatatatg
    32761 gcggcgatga cctttgtcac gttacccggt caggtcggtc cgctgctcgg tccggcgctc
    32821 ggcggtctgc tggtggagta cgcgtcgtgg cactggatct ttttgatcaa cattccggtg
    32881 gggattatcg gtgcgatcgc cacattgatg ttaatgccga actacaccat gcagacgcgg
    32941 cgctttgatc tttccggctt tttattgctg gcggttggca tggcggtatt aaccctggcg
    33001 ctggacggca gtaaaggtac aggtttatcg ccgctggcga ttgctggcct ggtcgcagtt
    33061 ggcgtggtgg cactggtgct ttatctgctg cacgccagaa ataacaaccg cgccctgttc
    33121 agtctgaaac tgttccgcac tcgtaccttt tcgctgggcc tggcggggag ctttgccgga
    33181 cgtattggca gtggcatgtt gccctttatg acaccggttt tcctgcaaat tggcctcggt
    33241 ttctcgccgt ttcatgccgg actgatgatg atcccgatgg tgcttggcag catgggaatg
    33301 aagcgaattg tggttcaggt ggtgaatcgc tttggttatc gtcgggtact ggtagcgacc
    33361 acgctgggtc tgtcgctggt caccctgttg tttatgacta ccgctctgtt gggctggtac
    33421 tacgttttgc cgttcgtcct gtttttacaa ggaatggtca actcaacgcg tttctcctcc
    33481 atgaacaccc tgacgctgaa agatctcccg gacaatctgg cgagcagcgg aaacagcctg
    33541 ctgtcgatga ttatgcaatt gtcgatgagt atcggcgtca ctatcgccgg gctgttgctg
    33601 ggactttttg gttcacagca tgtcagcgtc gacagcggca ccacacaaac cgtctttatg
    33661 tacacctggc ttagcatggc gttgatcatc gcccttccgg cgttcatctt tgccagagtg
    33721 ccgaacgata cgcatcaaaa tgtagctatt tcgcggcgaa aaaggagcgc gcaatgaagt
    33781 tctggcgacc cggtattacc ggcaaactgt ttctggcgat tttcgccacc tgcattgtct
    33841 tgctgatcag tatgcactgg gcggtgcgta tcagttttga gcgtggcttt attgattaca
    33901 tcaagcatgg taatgaacaa cgattacaac tgttaagtga tgcgcttggc gagcagtatg
    33961 cgcagcatgg caactggcgc ttcctgcgca acaatgatcg ctttgtcttt cagatcctgc
    34021 gttcatttga acacgataat tcggaagata aacccggccc gggtatgcca ccgcacggct
    34081 ggcgtaccca gttctgggtg gttgatcaaa acaacaaagt gctggttggt ccgcgagcgc
    34141 cgattccacc tgacggtaca cggcgaccca ttctggtcaa cggtgcggaa gttggcgcgg
    34201 tgatcgcctc ccccgttgag cggttaacgc gcaatactga tatcaatttc gataaacaac
    34261 agcggcaaac cagctggctg atcgtcgccc tggcaacgtt actcgcggcg ctcgccacct
    34321 ttctgctggc gcgcggtttg ctggcaccgg taaaacgact tgtcgatggc acgcacaaac
    34381 tggcggcggg cgatttcact acccgcgtaa cgcccaccag tgaagatgaa ctgggcaaac
    34441 tggcgcaaga cttcaaccag cttgccagca cgctggagaa aaaccagcaa atgcggcgcg
    34501 attttatggc cgatatttca cacgaactgc gtacgccatt agcggtgctg cgcggtgaac
    34561 tggaagccat tcaagatggc gtgcgcaaat tcacgccgga gacggtggcg tctttacagg
    34621 cggaagtcgg tacactgact aaactggttg acgatcttca tcagttgtcg atgtctgatg
    34681 aaggcgctct cgcctatcaa aaagcaccgg tagatttgat cccactgctg gaagtggcgg
    34741 gcggcgcatt tcgcgaacga tttgccagcc gtggcctgaa actgcagttt tccctgccag
    34801 acagtattac cgtatttggc gatcgcgacc gtttaatgca gttattcaat aacttactcg
    34861 aaaacagcct gcgctacact gatagcggcg gcagcctgaa aatctctgcc gagcagcacg
    34921 acaaaacggt gcgcctgacc tttgccgaca gtgcgccagg tgtcagtgac gagcagctac
    34981 aaaaattatt tgaacgtttt tatcgcaccg aaggttcccg caaccgcgcc agcggtggtt
    35041 ccgggctggg gctggcgatt tgcctgaaca ttgttgaagc acataatggc cgcattattg
    35101 ctgcccattc gccttttggc ggggtaagca ttacagtaga gttaccgctg gaacgggatt
    35161 tacagagaga agtatgaccg agttaccaat cgacgaaaac acaccgcgta ttttgatcgt
    35221 ggaagatgaa ccgaagctgg ggcagttgct cattgattat ctgcgtgctg cgagctatgc
    35281 gccgacgctt atcagccacg gcgatcaggt actgccgtat gtgcgccaga caccaccgga
    35341 tctgatcctg ttagatctga tgctccctgg caccgatggc ctgacgctgt gccgggaaat
    35401 tcgtcgtttt tctgacattc cgatcgtgat ggtgacggca aaaatcgaag agatcgatcg
    35461 cctgctgggg ctggagattg gcgcagatga ttatatctgt aagccgtaca gcccacggga
    35521 agtggtagcg cgcgtcaaaa ccattttgcg ccgttgcaaa ccgcagcgcg agttgcagca
    35581 acaggatgct gaaagcccgt tgattatcga cgaaggtcgt tttcaggctt catggcgcgg
    35641 taaaatgctt gacctgacgc ctgcggaatt tcgtctgctg aaaacgctct ctcatgaacc
    35701 aggaaaagtg ttctcccgcg agcatttgct caatcatctt tatgacgact accgcgtagt
    35761 aaccgaccgc accatcgaca gccacattaa aaacctgcgc cgcaagctgg aatctctcga
    35821 cgccgaacag tcatttatcc gcgccgttta cggcgttggt taccgctggg aagccgacgc
    35881 ctgccgcatc gtttagtttt agcgacatga ctttgttagc cggagatggc gttcagacca
    35941 gatccggcaa cattatccca cgcatggtca gcaaactgac attatctctc cgccctggca
    36001 ggcatcagaa aatcgctcat actttaatcg gtaaacagca cctttagatg caatttcaat
    36061 caaggagtca ttatggctgg ttggtttgaa ctcagtaaga gcagtgataa tcagttccgg
    36121 tttgtgctaa aagcgggcaa tggtgagact atcctcacca gcgagctgta tacctcaaaa
    36181 gcctctgcgg aaaagggcat cgcgtcggtg cgtagcaaca gcccgcaaga agaacgctat
    36241 gagaaaaaaa cggcaagtaa cggcaaattc tatttcaatc tgaaagccgc taatcatcaa
    36301 attatcggct ccagccagat gtacgccacc gcgcaatctc gtgaaaccgg aattgcctcc
    36361 gttaaagcca atggcacaag ccagacggtg aaagacaata cgtaattacg atgccgggcg
    36421 tgggttgttg gcgtccggct ttatatccaa ataacgctta gttattaata attaagagta
    36481 accgccgcca ttaaaatagt gggcactgac gagcactcgt tgtgctttct ttgtttacca
    36541 tcccatactt atcctcctga acatgttcat gtgccaaaat atcttctaat actttcgtga
    36601 cgctatccgg tttatgacat acactgatgt aagattttta cttacaggcg ggcgtaaaat
    36661 ggccagaacg atgacggttg atctcggcga tgagttgcgt gaatttatcg agtccttaat
    36721 tgaatccggc gactatcgca cccaaagcga agtgatccgt gagtcactgc gattacttcg
    36781 agaaaagcaa gcagagtctc gcctgcaagc gttacgtgac atgctcgcag aagggttgag
    36841 tagtggtgaa gctcagccgt gggaaaagga cgcgttctta cggaaggtga aagcagggat
    36901 aaggaaataa tgtgcgtatt attaaactca tgccaaaagc caatgaggat ttagaaggca
    36961 tctggtatta cagctatcac catttcggcg aaccacaagc cgacagatat gtggaacatc
    37021 tttcagacgt tctccagatt ctgagtaaca ataatatagg tacgcccaga cctgaattag
    37081 gcgaaggtat ttttgttctt ccttttgaac gccacgtcat ttatttcctg caatcaccag
    37141 gggaaattat cgtcattcgt atccttaacc aaaaccagga cgccaccaga catttacact
    37201 ggagctaaac ccgccgattg cgctacaatg cccgccctta aagtgggggc actcccctaa
    37261 ccgcttcatc aggtgaagcg gatctgacct gtcatcagaa cgagagaatt atgtttaaac
    37321 cggaactcct ttccccggcg ggaacgctga aaaatatgcg ttacgctttc gcttatggcg
    37381 cagatgctgt ttatgcgggc cagccgcgtt attccctgcg tgtgcgcaac aacgaattca
    37441 accacgaaaa tcttcagctc ggcatcaatg aagcccacgc gctggggaaa aagttttatg
    37501 tcgtggtcaa cattgcaccg cacaacgcca agctgaaaac ctttatccgt gacctgaaac
    37561 cggtggtgga aatggggccg gatgcgctga ttatgtccga tccagggctg attatgctgg
    37621 tgcgtgagca cttccctgaa atgccgatcc acctttcggt gcaggctaac gccgtgaact
    37681 gggcgacggt gaaattctgg cagcaaatgg gcctgacccg cgtgatcctc tctcgcgagc
    37741 tgtcgctgga agagattgaa gagatccgca atcaggtgcc ggatatggag atcgagatct
    37801 tcgttcacgg cgcgctgtgc atggcctact ccggtcgctg cctgctctct ggctatatca
    37861 acaagcgcga cccgaaccag ggcacctgca ccaacgcctg ccgctgggag tacaacgtcc
    37921 aggaagggaa agaagatgat gttggcaaca tcgtacacaa gtacgagccg attccggtgc
    37981 aaaatgttga gccgacgcta ggtatcggcg caccaaccga caaagtgttt atgatcgaag
    38041 aggcccagcg tccgggcgag tatatgaccg cgtttgaaga tgagcacggc acttacatca
    38101 tgaactcgaa agatctgcgc gccatcgccc atgtagaacg cctgaccaaa atgggcgtgc
    38161 attcgctgaa aatcgaaggt cgtaccaaat ctttctacta ttgtgcacgc accgcacagg
    38221 tttaccgcaa agctatcgat gacgccgctg cgggaaaacc gttcgatacc agcctgctgg
    38281 aaactctgga aggtctggcg catcgtggct ataccgaagg tttcctgcgt cgtcatactc
    38341 acgacgatta tcagaactac gaatacggtt attcagtttc tgaccgccag cagtttgttg
    38401 gtgagtttac cggtgagcgc aagggggacc tcgcggcggt agcggtgaaa aataaattct
    38461 ccgttggcga cagccttgag ctgatgacgc cgcaaggcaa cattaatttt acccttgagc
    38521 acatggaaaa cgccaaaggc gaagctatgc cgatagcacc aggcgatggt tatactgtgt
    38581 ggctcccggt cccgcaggat cttgagctca attacgcgct gctgatgcgt aatttctccg
    38641 gggaaaccac gcgtaatccc cacggtaagt gattaatttc gattattttt cccggatgga
    38701 aaattcttag aaaccgatca catacagctg catttattaa ggttatcatc cgtttcgctg
    38761 aaaaacataa cccataaaat gctagctgta ccaggaacca cctccttagc ctgtgtaatc
    38821 tcccttacac gggcttattt ttttatgcat aagccctatc tctggtaacc gtcttccatt
    38881 gaccacatcg atagaatctc ccttcatagc acgatgcctt tcacgtaacg gcatcgtgct
    38941 cgcacaggtt ccggctaagc acaaccagaa cgcgcatgtt tgacgcttac caaaaaatat
    39001 tctcactctc cacatttgaa tgtcagacga gcgacgccat gtaatcctgc accttctgtc
    39061 ttcaggtcaa ctatctgcat ttttttgccc tgagtaacac agaaatgggc tgcatcattt
    39121 tttactatat tttctgcacc agatattctg cccctggcta aagaagcttc ggcttcggtg
    39181 tagtattgat tatcgagttt acgctgaata ttacttttat atgcaagacc aaatttaccg
    39241 atacttgtct catcattatg cacagcacaa ccagac
//
LOCUS       DAPGUL010000034        38335 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.034, whole genome shotgun sequence.
ACCESSION   DAPGUL010000034 DAPGUL010000000
VERSION     DAPGUL010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 38335)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38335)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38335
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.034"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..745
                     /locus_tag="RHX21_001907"
     CDS             <1..745
                     /locus_tag="RHX21_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987089.1"
                     /translation="FRCATQIDKNSYQVLSSKNENVHAMDKFLISFSLKDNGAEYIMT
                     LRGSGFEYEEIPITINEYNSFMDFKNREFPLEQNRRLYAWDILQKKQSDIPERIKGYI
                     RQAFGDVSLGYAVLDDIVSKLKRGKFDLQIPGGGIKECDGWYIYEKIIDDNFAIVIES
                     LGFALKIYGGDERFRNGSSVVLEDEDYSLIYNFLVNAGCQQVELAEQVDAIVSANLAA
                     DSDITEEKICEKYKSTIEAFKKKQLALPV"
     gene            complement(835..1389)
                     /locus_tag="RHX21_001908"
     CDS             complement(835..1389)
                     /locus_tag="RHX21_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtfJ family protein"
                     /protein_id="HDV1987090.1"
                     /translation="MTLRKILALTCLLLPMMASAHQFETGQRVPPIGITDRGELVLDK
                     DQFSYKTWNSAQLVGKVRVLQHIAGRTSAKEKNATLIEAIKAAKLPHDRYQTTTIVNT
                     DDAIPGSGMFVRSSLESNKKLYPWSQFIVDSNGVARGAWQLDEESSAVVVLDKDGRVQ
                     WAKDGALTPEEVQQVMDLLQKLLK"
     gene            1714..1920
                     /locus_tag="RHX21_001909"
     CDS             1714..1920
                     /locus_tag="RHX21_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1107 domain-containing protein"
                     /protein_id="HDV1987091.1"
                     /translation="MKIFQRYNPLQVAKYVKILFRGRLYIKDVGAFEFDKGKILIPKV
                     KDKLHLSVMSEVNRQVMRLQTEMA"
     gene            complement(1982..3325)
                     /locus_tag="RHX21_001910"
     CDS             complement(1982..3325)
                     /locus_tag="RHX21_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDV1987092.1"
                     /translation="MLNSILVILCLIAVSAFFSMSEISLAASRKIKLKLLADEGNINA
                     QRVLNMQENPGMFFTVVQIGLNAVAILGGIVGDAAFSPAFHSLFSRYMSAELSEQLSF
                     ILSFSLVTGMFILFADLTPKRIGMIAPEAVALRIINPMRFCLYVCTPLVWFFNGLANM
                     IFRIFKLPMVRKDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTP
                     RENVIWFDLHEDEQSLKNKVAEHPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSLA
                     LNSGVQIRNTLIVPDTLTLSEALESFKTAGEDFAVIMNEYALVVGIITLNDVMTTLMG
                     DLVGQGLEEQIVARDENSWLIDGGTPIDDVMRVLDIDEFPQSGNYETIGGFMMFMLRK
                     IPKRTDSVKFAGYKFEVVDIDNYRIDQLLVTRIDSKATALSPKLPDAKDKEESVA"
     gene            complement(3648..4286)
                     /gene="msrA"
                     /locus_tag="RHX21_001911"
     CDS             complement(3648..4286)
                     /gene="msrA"
                     /locus_tag="RHX21_001911"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDV1987093.1"
                     /translation="MSLFDKKHLVSPADALPGRNTPMPVATLHAVNGHSMTNVPDGME
                     IAIFAMGCFWGVERLFWQLPGVYSTAAGYTGGYTPNPTYREVCSGDTGHAEAVRIVYD
                     PSVISYEQLLQVFWENHDPAQGMRQGNDHGTQYRSAIYPLTPEQDAAARASLERFQAA
                     MLAADDDRRITTEIANATPFYYAEDDHQQYLHKNPYGYCGIGGIGVCLPPEA"
     gene            4492..6225
                     /gene="tamA"
                     /locus_tag="RHX21_001912"
     CDS             4492..6225
                     /gene="tamA"
                     /locus_tag="RHX21_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex protein TamA"
                     /protein_id="HDV1987094.1"
                     /translation="MRYIRQLCCVSLLCLSGSTVAANVRLQVEGLSGQLEKNVRAQLS
                     TIESDEVTPDRRFRARVDDAIREGLKALGYYQPTIEFDLRPPPKKGRQVLIAKVTPGV
                     PVLIGGTDVVLRGGARTDKDYLKLLDTRPAIGTVLNQGDYENFKKSLTSIALRKGYFD
                     SEFTKAQLGIALGLHKAFWDIDYNSGERYRFGHVTFEGSQIRDEYLQNLVPFKEGDEY
                     ESKDLAELNRRLSATGWFNSVVVAPQFDKARETKVLPLTGVVSPRTENTIETGVGYST
                     DVGPRVKATWKKPWMNSYGHSLTTSTSISAPEQTLDFSYKMPLLKNPLEQYYLVQGGF
                     KRTDLNDTESDSTTLVASRYWDLSSGWQRAINLRWSLDHFTQGEITNTTMLFYPGVMI
                     SRTRSRGGLMPTWGDSQRYSIDYSNTAWGSDVDFSVFQAQNVWIRTLYDRHRFVTRGT
                     LGWIETGDFDKVPPDLRFFAGGDRSIRGYKYKSIAPKYANGDLKGASKLITGSLEYQY
                     NVTGKWWGAVFVDSGEAVSDIRRSDFKTGTGVGVRWESPVGPIKLDFAVPVADKDEHG
                     LQFYIGLGPEL"
     gene            6222..10001
                     /gene="tamB"
                     /locus_tag="RHX21_001913"
     CDS             6222..10001
                     /gene="tamB"
                     /locus_tag="RHX21_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex protein TamB"
                     /protein_id="HDV1987095.1"
                     /translation="MSLWKKISLGVVIVILLLLGSVAFLVGTTSGLHLVFKAADRWVP
                     GLDIGKVTGGWRDLTLSDVRYEQPGVAVKAGNLHLAVGLECLWNSSVCINDLALKDIQ
                     VNIDSKKMPPSEQVEEEEDSGPLDLSTPYPITLTRVALDNVNIKIDDTTVSVMDFTSG
                     LNWQEKTLTLKPTSLKGLLIALPKVAEVAQEEVVEPKIENPQPDEKPLGETLKDLFSR
                     PVLPEMTDVHLPLNLNIEEFKGEQLRVTGDTDITVRTMLLKVSSIDGNTKLDALDIDS
                     NQGIVNASGTAQLSDNWPVDITLNSTLNVEPLKGEKVKLKVGGALREQLEIGVNLSGP
                     VDMDLRAQTRLAEAGLPLNVEVNSKQLYWPFTGEKQYQADDLKLKLTGKMTDYTLSMR
                     TAVKGQEIPPATITLDAKGNEQQVNLDKLTVAALEGKTELKALLDWQQAISWRGELTL
                     NGINTAKEFPEWPSKLNGLIKTRGSLYGGTWQMEVPELKLTGNVKQNKVNVDGTLKGN
                     SYMQWKIPGLHLELGPNSAEVKGELGVKDLNLDATINAPGLDNALPGLGGTAKGLVKV
                     RGTVEAPQLLADITARGLRWQELSVAQVRVEGDIKSTDQIAGKLDVRVEQISQPDVSI
                     NLVTLNAKGSEKQHELQLRIQGEPVSGQLNLTGSFDRKEERWKGTLSNTRFQTPVGPW
                     SLTRDIALDYRNKEQKISIGPHCWLNPNAELCVPQTIDAGAEGRAVVNLNRFDLAMLK
                     PFMPETTQASGIFTGKADVAWDTTKEGLPQGSITLSGRNVQVTQTVNDAALPVAFQTL
                     NLTAELRNNRAELGWTIRLTNNGQFDGQVQVADPQGRRNLGGNVNIRNFNLAMINPIF
                     TRGEKAAGMVSANLRLGGDVQSPQLFGQLQVTGVDIDGNFMPFDMQPSQLAVNFNGMR
                     STLAGTVRTQQGEIYLNGDADWSQIENWRARVTAKGSKVRITVPPMVRMDVSPDVVFE
                     ATPNLFTLDGRVDVPWARIVVHDLPESAVGVSSDVVMLNDNLQPEEAKTASIPINSNL
                     IVHVGNNVRIDAFGLKARLTGDLNVVQDKQGLGLNGQINIPEGRFHAYGQDLIVRKGE
                     LLFSGPPDQPYLNIEAIRNPDATEDDVIAGVRVTGLADEPKAEIFSDPAMSQQAALSY
                     LLRGQGLESDQSDSAAMTSMLIGLGVAQSGQIVGKIGETFGVSNLALDTQGVGDSSQV
                     VVSGYVLPGLQVKYGVGIFDSIATLTLRYRLMPKLYLEAVSGVDQALDLLYQFEF"
     gene            10004..10345
                     /locus_tag="RHX21_001914"
     CDS             10004..10345
                     /locus_tag="RHX21_001914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcyclotransferase"
                     /protein_id="HDV1987096.1"
                     /translation="MRIFVYGSLRHKQGNSHWMTNAQLLGDFSIDNYQLYSLGHYPGA
                     VPGNGTVHGEVYRIDNATLAELDALRTRGGEYARQLIQTPYGSAWMYVYQRPVDGLKL
                     IESGDWLDRDK"
     gene            10557..10808
                     /gene="chpS"
                     /locus_tag="RHX21_001915"
     CDS             10557..10808
                     /gene="chpS"
                     /locus_tag="RHX21_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418645.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin ChpS"
                     /protein_id="HDV1987097.1"
                     /translation="MRITIKRWGNSSGMVIPNVVMKELNLRPGQSVEAQVSNNQLILT
                     PISRRYSLDELLAQCDMNATELSEQDVWGKSTPAGDEIW"
     gene            10802..11152
                     /gene="chpB"
                     /locus_tag="RHX21_001916"
     CDS             10802..11152
                     /gene="chpB"
                     /locus_tag="RHX21_001916"
                     /EC_number="4.6.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease toxin ChpB"
                     /protein_id="HDV1987098.1"
                     /translation="MVKKSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLG
                     MTLVAPITQGGNFARYAGFSVPLHCEEGDVHGVVLVNQVRMMDLRARLAKRIGLAAGE
                     VVEEALLRLQAVVE"
     gene            complement(11231..11761)
                     /gene="ppa"
                     /locus_tag="RHX21_001917"
     CDS             complement(11231..11761)
                     /gene="ppa"
                     /locus_tag="RHX21_001917"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001739810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic diphosphatase"
                     /protein_id="HDV1987099.1"
                     /translation="MSLLNVPAGKDLPEDIYVVIEIPANADPIKYEIDKESGALFVDR
                     FMSTAMFYPCNYGYINHTLSLDGDPVDVLVPTPYPLQPGSVIRCRPVGVLKMTDEAGE
                     DAKLVAVPHSKLSKEYDHIKDVNDLPELLKAQIAHFFEHYKDLEKGKWVKVEGWENAE
                     AAKAEIVASFERAKNK"
     gene            12071..13027
                     /gene="ytfQ"
                     /locus_tag="RHX21_001918"
     CDS             12071..13027
                     /gene="ytfQ"
                     /locus_tag="RHX21_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactofuranose ABC transporter
                     substrate-binding protein YtfQ"
                     /protein_id="HDV1987100.1"
                     /translation="MWKRLLVVSAVSAAMSSMALAAPLTVGFSQVGSESGWRAAETNV
                     AKSEAEKRGITLKIADGQQKQENQIKAVRSFVAQGVDAIFIAPVVATGWEPVLKEAKD
                     AEIPVFLLDRSIDVKDKSLYMTTVTADNILEGKLIGDWLVKEVNGKPCNVVELQGTVG
                     ASVAIDRKKGFAEAIKNAPNIKIIRSQSGDFTRSKGKEVMESFIKAENNGKNICMVYA
                     HNDDMVIGAIQAIKEAGLKPGKDILTGSIDGVPDIYKAMIDGEANASVELTPNMAGPA
                     FDALEKYKKDGTMPEKLTLTKSTLYLPDTAKEELEKKKNMGY"
     gene            13167..14669
                     /locus_tag="RHX21_001919"
     CDS             13167..14669
                     /locus_tag="RHX21_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDV1987101.1"
                     /translation="MTTDQHQEILRTEGLSKFFPGVKALDNVNFSLRRGEIMALLGEN
                     GAGKSTLIKALTGVYHADCGTIWLEGQTISPKNTAHAQQLGIGTVYQEVNLLPNMSVA
                     DNLFIGREPKRFGLLRRKEMEKRATELMASYGFSLDVREPLNRFSVAMQQIVAICRAI
                     DLSAKVLILDEPTASLDTQEVELLFGLMCQLRDRGVSLIFVTHFLDQVYQVSDRITVL
                     RNGSFVGCRETRELPQIELVKMMLGRELDTHALQRAGRTLLSDKPVAAFKNYGKKGTI
                     APFDLEVRPGEIVGLAGLLGSGRTETAEVIFGIKPADSGTALIKGKQQTLRSPHQASV
                     LGIGFCPEDRKTDGIIAAASVRENIILALQAQRGWLRPISRKEQQEIAQRFIRQLGIR
                     TPSTEQPIEFLSGGNQQKVLLSRWLLTRPQFLILDEPTRGIDVGAHAEIIRLIETLCA
                     DGLALLVISSELEELVGYADRVIIMRDRKQVAEIPLAELSVPAIMNAIAA"
     gene            14683..15705
                     /locus_tag="RHX21_001920"
     CDS             14683..15705
                     /locus_tag="RHX21_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313234.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV1987102.1"
                     /translation="MPQSLPDTTPPKRRFRWPTGMPQLAALLLVLLVDSLVAPHFWQV
                     VLQDGRLFGSPIDILNRAAPVALLAIGMTLVIATGGIDLSVGAVMAIAGATTAAMTVA
                     GFSLPIVLLSALGTGILAGLWNGILVAILKIQPFVATLILMVAGRGVAQLITSGQIVT
                     FNSPDLSWFGSGSLLFLPTPVIIAVLTLLLFWLLTRKTALGMFIEAVGINMRAAKNAG
                     VNTRIIVMFTYVLSGLCAAIAGIIVAADIRGADANNAGLWLELDAILAVVIGGGSLMG
                     GRFNLLLSVVGALIIQGMNTGILLSGFPPEMNQVVKAVVVLCVLIVQSQRFISLIKGV
                     RSRDKT"
     gene            15692..16687
                     /gene="yjfF"
                     /locus_tag="RHX21_001921"
     CDS             15692..16687
                     /gene="yjfF"
                     /locus_tag="RHX21_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease YjfF"
                     /protein_id="HDV1987103.1"
                     /translation="MIKRNLPLMITIGVFVLGYFYCLTQFPGFASTRVICNILTDNAF
                     LGIIAVGMTFVILSGGIDLSVGSVIAFTGVFLAKVIGDFGLSPLLAFPLVLVMGCAFG
                     AFMGLLIDALKIPAFIITLAGMFFLRGVSYLVSEESIPINHPVYDTLSSLAWKIPGGG
                     RLSAMGLLMLAVVVIGIFLAHRTRFGNQVYAIGGNATSANLMGISTRSTTIRIYMLST
                     GLATLAGIVFSIYTQAGYALAGVGVELDAIASVVIGGTLLSGGVGTVLGTLFGVAIQG
                     LIQTYINFDGTLSSWWTKIAIGILLFIFIALQRGLTVLWENRQSSPVTRVNIAQR"
     gene            complement(16720..17718)
                     /gene="fbp"
                     /locus_tag="RHX21_001922"
     CDS             complement(16720..17718)
                     /gene="fbp"
                     /locus_tag="RHX21_001922"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 fructose-bisphosphatase"
                     /protein_id="HDV1987104.1"
                     /translation="MKTLGEFIVEKQHEFSHATGELTALLSAIKLGAKIIHRDINKAG
                     LVDILGASGAENVQGEVQQKLDLFANEKLKAALKARDIVAGIASEEEDEIVVFEGCEH
                     AKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNKQVAAGYVV
                     YGSSTMLVYTTGCGVHAFTYDPSLGVFCLCQERMRFPEKGKTYSINEGNYIKFPNGVK
                     KYIKFCQEEDKSTNRPYTSRYIGSLVADFHRNLLKGGIYLYPSTASHPDGKLRLLYEC
                     NPMAFLAEQAGGKASDGKERILDIIPETLHQRRSFFVGNDHMVEDVERFIREFPDA"
     gene            17894..19267
                     /gene="mpl"
                     /locus_tag="RHX21_001923"
     CDS             17894..19267
                     /gene="mpl"
                     /locus_tag="RHX21_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-
                     meso-diaminopimelate ligase"
                     /protein_id="HDV1987105.1"
                     /translation="MRIHILGICGTFMGGLAMLARQLGHEVTGSDANVYPPMSTLLEK
                     QGIELIQGYDASQLDPQPDLVIIGNAMTRGNPCVEAVLEKNIPYMSGPQWLHDFVLRD
                     RWVLAVAGTHGKTTTAGMATWILEQCGYKPGFVIGGVPGNFEVSARLGESDFFVIEAD
                     EYDCAFFDKRSKFVHYCPRTLILNNLEFDHADIFDDLKAIQKQFHHLVRIVPGQGRII
                     WPENDINLKQTMAMGCWSEQELVGEQGHWQAKKLTTDASEWEVLLDGEKVGEVKWSLV
                     GEHNMHNGLMAIAAARHVGVAPADAANALGSFINARRRLELRGEANGVTVYDDFAHHP
                     TAILATLAALRGKVGGTARIIAVLEPRSNTMKMGICKDDLAPSLGRADEVFLLQPAHI
                     PWQVAEVAEACVQPAHWSGDVDTLADMVVKTAQPGDHILVMSNGGFGGIHQKLLDGLA
                     KKAEAAQ"
     gene            complement(19423..19974)
                     /locus_tag="RHX21_001924"
     CDS             complement(19423..19974)
                     /locus_tag="RHX21_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated protein"
                     /protein_id="HDV1987106.1"
                     /translation="MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGA
                     EIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALD
                     KLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKE
                     GNKPPKSARQIFQYLRELAENEG"
     gene            20068..21420
                     /gene="pmbA"
                     /locus_tag="RHX21_001925"
     CDS             20068..21420
                     /gene="pmbA"
                     /locus_tag="RHX21_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease PmbA"
                     /protein_id="HDV1987107.1"
                     /translation="MALAMKVISQVEAQRKILEEAVSTALELASGKSDGAEVAVSKTT
                     GISVSTRYGEVENVEFNSDGALGITVYHQNRKGSASSTDLSPQAIARTVQAALDIARY
                     TSPDPCAGVADKELLAFDAPDLDLFHPAEVSPDEAIELAARAEQAALQADKRITNTEG
                     GSFNSHYGVKVFGNSHGMLQGYCSTRHSLSSCVIAEENGDMERDYAYTIGRAMSDLQT
                     PEWVGADCARRTLSRLSPRKLSTMKAPVIFANEVATGLFGHLVGAIAGGSVYRKSTFL
                     LDSLGKQILPDWLTIEEHPHLLKGLASTPFDSEGVRTERRDIIKDGILTQWLLTSYSA
                     RKLGLKSTGHAGGIHNWRIAGQGLSFEQMLKEMGTGLVVTELMGQGVSAITGDYSRGA
                     AGFWVENGEIQYPVSEITIAGNLKDMWRNIVTVGNDIETRSNIQCGSVLLPEMKIAGQ
                     "
     gene            21604..21990
                     /gene="cybC"
                     /locus_tag="RHX21_001926"
     CDS             21604..21990
                     /gene="cybC"
                     /locus_tag="RHX21_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313240.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b562"
                     /protein_id="HDV1987108.1"
                     /translation="MRKSLLAILAVSSLVFSSASFAADLEDNMETLNDNLKVVEKADN
                     AAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLAN
                     EGKVKEAQAAAEQLKTTRNSYHKKYR"
     gene            complement(22035..22499)
                     /gene="nrdG"
                     /locus_tag="RHX21_001927"
     CDS             complement(22035..22499)
                     /gene="nrdG"
                     /locus_tag="RHX21_001927"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate
                     reductase-activating protein"
                     /protein_id="HDV1987109.1"
                     /translation="MNYHQYYPVDIVNGPGTRCTLFVSGCVHECPGCYNKSTWRVNSG
                     QPFTKAMEDQIINDLNDTRIKRQGISLSGGDPLHPQNVPDILKLVQRIRAECPGKDIW
                     VWTGYKLDELNAAQMQVVDLINVLVDGKFVQDLKDPSLIWRGSSNQVVHHLR"
     gene            complement(22657..24795)
                     /gene="nrdD"
                     /locus_tag="RHX21_001928"
     CDS             complement(22657..24795)
                     /gene="nrdD"
                     /locus_tag="RHX21_001928"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HDV1987110.1"
                     /translation="MTPHVMKRDGCKVPFKSERIKEAILRAAKAAEVDDADYCATVAA
                     VVSEQMQGRNQVDINEIQTAVENQLMSGPYKQLARAYIEYRHDRDIEREKRGRLNQEI
                     RGLVEQTNASLLNENANKDSKVIPTQRDLLAGIVAKHYARQHLLPRDVVQAHERGDIH
                     YHDLDYSPFFPMFNCMLIDLKGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASH
                     IYGGTTINRIDEVLAPFVTASYNKHRKTAEEWNIPDAEGYANSRTIKECYDAFQSLEY
                     EVNTLHTANGQTPFVTFGFGLGTSWESRLIQESILRNRIAGLGKNRKTAVFPKLVFAI
                     RDGLNHKKGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGVWE
                     NENGEQIHDGRNNLGVISLNLPRIALEAKGDEATFWKLLDERLVLARKALMTRIARLE
                     GVKARVAPILYMEGACGVRLNADDDVSEIFKNGRASISLGYIGIHETINALFGGEHVY
                     DNEQLRAKGIAIVERLRQAVDQWKEETGYGFSLYSTPSENLCDRFCRLDTAEFGVVPG
                     VTDKGYYTNSFHLDVEKKVNPYDKIDFEAPYPPLANGGFICYGEYPNIQHNLKALEDV
                     WDYSYQHVPYYGTNTPIDECYECGFTGEFECTSKGFTCPKCGNHDASRVSVTRRVCGY
                     LGSPDARPFNAGKQEEVKRRVKHLGNGQIG"
     gene            complement(25189..26844)
                     /gene="treC"
                     /locus_tag="RHX21_001929"
     CDS             complement(25189..26844)
                     /gene="treC"
                     /locus_tag="RHX21_001929"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HDV1987111.1"
                     /translation="MTHLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQHLDYLHK
                     LGVDAIWLTPFYVSPQVDNGYDVANYTAIDPTYGTLDDFDELVTQAKSRGIRIILDMV
                     FNHTSTQHAWFREALNKESPYRQFYIWRDGEPETPPNNWRSKFGGSAWRWHAESEQYY
                     LHLFAPEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLISKDPRFPEDLDGD
                     GRRFYTDGPRAHEFLHEMNRDVFTPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFN
                     FHHLKVDYPGGEKWTLAKPDFVALKTLFRHWQQGMHNVAWNALFWCNHDQPRIVSRFG
                     DEGEYRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESLNMFAELR
                     NDGRDADELLAILASKSRDNSRTPMQWSNGDNAGFTAGEPWIGLGDNYQQINVEAALA
                     DDSSVFYTYQKLIALRKQEAILTWGNYQDLLPNSPVLWCYRREWKGQTLLVIANLSRE
                     IQPWQAGQMRGNWQLVMHNYEEASPQPCAMNLRPFEAVWWLQK"
     gene            complement(26894..28315)
                     /gene="treB"
                     /locus_tag="RHX21_001930"
     CDS             complement(26894..28315)
                     /gene="treB"
                     /locus_tag="RHX21_001930"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS trehalose transporter subunit IIBC"
                     /protein_id="HDV1987112.1"
                     /translation="MMSKINQTDIDRLIELVGGRGNIATVSHCITRLRFVLNQPANAR
                     PKEIEQLPMVKGCFTNAGQFQVVIGTNVGDYYQALIASTGQAQVDKEQVKKAARQNMK
                     WHEQLISHFAEIFFPLLPALISGGLILGFRNVIGDLPMSNGQTLAQMYPSLQTIYDFL
                     WLIGEAIFFYLPVGICWSAVKKMGGTPILGIVLGVTLVSPQLMNAYLLGQQLPEVWDF
                     GMFSIAKVGYQAQVIPALLAGLALGVIETRLKRIVPDYLYLVVVPVCSLILAVFLAHA
                     LIGPFGRMIGDGVAFAVRHLMTGSFAPIGAALFGFLYAPLVITGVHQTTLAIDLQMIQ
                     SMGGTPVWPLIALSNIAQGSAVIGIIISSRKHNEREISVPAAISAWLGVTEPAMYGIN
                     LKYRFPMLCAMIGSGLAGLLCGLNGVMANGIGVGGLPGILSIQPSYWQVFALAMAIAI
                     IIPIVLTSFIYQRKYRLGTLDIV"
     gene            complement(28434..29381)
                     /gene="treR"
                     /locus_tag="RHX21_001931"
     CDS             complement(28434..29381)
                     /gene="treR"
                     /locus_tag="RHX21_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HDV1987113.1"
                     /translation="MQNRLTIKDIARLSGVGKSTVSRVLNNESGVSQLTRERVEAVMN
                     QHGFSPSRSARAMRGQSDKVVAIIVTRLDSLSENLAVQTMLPAFYEQGYDPIMMESQF
                     SPQLVAEHLGVLKRRNIDGVVLFGFTGITEEMLAHWQSSLVLLARDAKGFASVCYDDE
                     GAIKILMQRLYDQGHRNISYLGVPHSDVTTGKRRHEAYLAFCKAHKLHPVAALPGLAM
                     KQGYENVAKVITPETTALLCATDTLALGASKYLQEQRIDTLQLASVGNTPLMKFLHPE
                     IVTVDPGYAEAGRQAACQLIAQVTGRSEPQQIIIPATLS"
     gene            29566..29619
                     /gene="mgtL"
                     /locus_tag="RHX21_001932"
     CDS             29566..29619
                     /gene="mgtL"
                     /locus_tag="RHX21_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003933616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mgtA regulatory leader peptide MgtL"
                     /protein_id="HDV1987114.1"
                     /translation="MEPDPTPLPRRRLKLFR"
     gene            29760..32456
                     /gene="mgtA"
                     /locus_tag="RHX21_001933"
     CDS             29760..32456
                     /gene="mgtA"
                     /locus_tag="RHX21_001933"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HDV1987115.1"
                     /translation="MFKEIFTRLTRHLPSRLVHRDPLPGAQQTVNTVVPPSLSAHCLK
                     MAVMPEEELWKTFDTHPEGLNQAEVESAREQHGENKLPAQQPSPWWVHLWVCYRNPFN
                     ILLTILGAISYATEDLFAAGVIALMVAISTLLNFIQEARSTKAADALKAMVSNTATVL
                     RVINDKGENGWLEIPIDQLVPGDIIKLAAGDMIPADLRILQARDLFVAQASLTGESLP
                     VEKAATTRQPEHSNPLECDTLCFMGTTVVSGTAQAMVIATGANTWFGQLAGRVSEQES
                     EPNAFQQGISRVSMLLIRFMLVMAPVVLLINGYTKGDWWEAALFALSVAVGLTPEMLP
                     MIVTSTLARGAVKLSKQKVIVKHLDAIQNFGAMDILCTDKTGTLTQDKIVLENHTDIS
                     GKTSERVLHSAWLNSHYQTGLKNLLDTAVLEGTDEESARSLVSRWQKIDEIPFDFERR
                     RMSVVVAENTEHHQLVCKGALQEILNVCSQVRHNGEIVPLDDIMLRKIKRVTDTLNRQ
                     GLRVVAVATKYLPAREGDYQRADESDLILEGYIAFLDPPKETTAPALKALKASGITVK
                     ILTGDSELVAAKVCHEVGLDAGEVVIGSDIEMLSDDELANLAQRTTLFARLTPMHKER
                     IVTLLKREGHVVGFMGDGINDAPALRAADIGISVDGAVDIAREAADIILLEKSLMVLE
                     EGVIEGRRTFANMLKYIKMTASSNFGNVFSVLVASAFLPFLPMLPLHLLIQNLLYDVS
                     QVAIPFDNVDDEQIQKPQRWNPADLGRFMIFFGPISSIFDILTFCLMWWVFHANTPET
                     QTLFQSGWFVVGLLSQTLIVHMIRTRRVPFIQSCASWPLMIMTVIVMIVGIALPFSPL
                     ASYLQLQALPLSYFPWLVAILAGYMTLTQLVKGFYSRRYGWQ"
     gene            complement(32662..33048)
                     /gene="ridA"
                     /locus_tag="RHX21_001934"
     CDS             complement(32662..33048)
                     /gene="ridA"
                     /locus_tag="RHX21_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418664.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminobutanoate/2-iminopropanoate deaminase"
                     /protein_id="HDV1987116.1"
                     /translation="MSKTIATENAPAAIGPYVQGVDLGNMIITSGQIPVNPKTGEVPA
                     DVAAQARQSLDNVKAIVEAAGLKVGDIVKTTVFVKDLNDFATVNATYEAFFTEHNAAF
                     PARSCVEVARLPKDVKIEIEAIAVRR"
     gene            complement(33121..33582)
                     /gene="pyrI"
                     /locus_tag="RHX21_001935"
     CDS             complement(33121..33582)
                     /gene="pyrI"
                     /locus_tag="RHX21_001935"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase regulatory
                     subunit"
                     /protein_id="HDV1987117.1"
                     /translation="MTHDNKLQVEAIKRGTVIDHIPAQIGFKLLSLFKLTETDQRITI
                     GLNLPSGEMGRKDLIKIENTFLSEDQVDQLALYAPQATVNRIDNYEVVGKSRPSLPER
                     IDNVLVCPNSNCISHAEPVSSSFAVRKRANDIALKCKYCEKEFSHNVVLAN"
     gene            complement(33595..34530)
                     /gene="pyrB"
                     /locus_tag="RHX21_001936"
     CDS             complement(33595..34530)
                     /gene="pyrB"
                     /locus_tag="RHX21_001936"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HDV1987118.1"
                     /translation="MANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLKHKV
                     IASCFFEASTRTRLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDA
                     IVMRHPQEGAARLATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAM
                     VGDLKYGRTVHSLTQALAKFDGNRFYFIAPDALAMPQYILDMLDEKGIAWSLHSSIEE
                     VMAEVDILYMTRVQKERLDPSEYANVKAQFVLRASDLHNAKANMKVLHPLPRVDEIAT
                     DVDKTPHAWYFQQAGNGIFARQALLALVLNRDLVL"
     gene            complement(34534..34668)
                     /gene="pyrL"
                     /locus_tag="RHX21_001937"
     CDS             complement(34534..34668)
                     /gene="pyrL"
                     /locus_tag="RHX21_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyr operon leader peptide"
                     /protein_id="HDV1987119.1"
                     /translation="MVQCVRHFVLPRLKKDAGLPFFFPLITHSQPLNRGAFFCPGVRR
                     "
     gene            complement(34949..35344)
                     /locus_tag="RHX21_001938"
     CDS             complement(34949..35344)
                     /locus_tag="RHX21_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDV1987120.1"
                     /translation="MVERTAVFPAGRHSLYAEHRYSAAIRSGDLLFVSGQVGSREDGT
                     PEPDFQQQVRLAFDNLHATLAAAGCTFDDIIDVTSFHTDPEKQFEDIMTVKNEIFSAP
                     PYPNWTAVGVTWLAGFDFEIKVIARIPEQ"
     gene            complement(35475..36188)
                     /gene="bdcA"
                     /locus_tag="RHX21_001939"
     CDS             complement(35475..36188)
                     /gene="bdcA"
                     /locus_tag="RHX21_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDV1987121.1"
                     /translation="MGAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAA
                     EHLAQETGATAVFTDSADRDAVIDVVRKSGALDILVVNAGIGVFGDALELNADDIDRL
                     FKINIHAPYHASVEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGL
                     ARDFGPRGITINVVQPGPIDTDANPANGPMRDMLHGFMAIKRHGQPEEVAGMVAWLAG
                     PEASFVTGAMHTIDGAFGA"
     gene            36259..36852
                     /locus_tag="RHX21_001940"
     CDS             36259..36852
                     /locus_tag="RHX21_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313255.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDV1987122.1"
                     /translation="MVTKKQSRVPGRPRRFAPEQAVSAAKVLFHQKGFDAVSVAEVTD
                     YLGINPPSLYAAFGNKAGLFSRVLNEYVGTEAIPLADILRDDRPVGECLAEVLKEAAR
                     RYSQNGGCAGCMVLEGIHSHDPQARDIAVQYYHAAETAIYDYIARRHPQSAQCVTDFM
                     STVMSGLSAKAREGHSIEQLCATAALAGEAIKTILKE"
     gene            36997..37449
                     /gene="tabA"
                     /locus_tag="RHX21_001941"
     CDS             36997..37449
                     /gene="tabA"
                     /locus_tag="RHX21_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313256.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin biofilm protein TabA"
                     /protein_id="HDV1987123.1"
                     /translation="MIIGNIHNLQPWLPQELRQAIEHIKAHVTAETPKGKHDIEGNRL
                     FYLISEDMTEPYEARRAEYHARYLDIQIVLKGQEGMTFSTQPAGTPDTDWLADKDIAF
                     LPEGVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPARVRKAVVKMLMA"
     gene            37572..>38335
                     /locus_tag="RHX21_001942"
     CDS             37572..>38335
                     /locus_tag="RHX21_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDV1987124.1"
                     /translation="MSKISDLNYSQHITLADNFKQKSEVLNTWRVGMNNFARNAEGQD
                     NTRNILDPKTFLEFLVKIFTLGYVDFSKRSNEAGRNMMAHIESSSYIKNNDGSEIMKF
                     VMNNPEGERADLSKVEIEITLSAFTTMGTRQGHTAIIFQQPDGSTNRYEGKSFERKDE
                     SSLHLITNKILACYQREANKEIARLLNIPQELNNSQDLNNSQVSCKDSVDSTITDLLE
                     KPLNNALLAIRKEHLLLMPYVCNESISYLLGEKGIL"
BASE COUNT         9303 a         9453 c        10286 g         9293 t
ORIGIN      
        1 ctttcgttgc gcaactcaga ttgataaaaa tagttatcag gtactttcat caaaaaatga
       61 aaatgttcac gccatggata agtttcttat cagtttcagc cttaaagata acggagccga
      121 atatataatg acattgcgag gcagtggatt tgaatacgaa gaaattccca taacaataaa
      181 tgagtataac tcattcatgg atttcaaaaa ccgcgagttt ccgttagaac aaaacagacg
      241 attgtatgcc tgggatattc tgcagaaaaa acagtctgac ataccggaaa ggattaaagg
      301 ttatattcgc caggcgtttg gtgacgtgtc tttaggttat gctgtattgg atgatatagt
      361 aagtaaatta aaacggggta aatttgacct ccaaattcca ggaggtggaa ttaaagaatg
      421 cgatggatgg tatatttacg aaaaaataat tgatgataat tttgccatag tcatagaatc
      481 tttgggcttt gcgcttaaaa tctatggagg ggatgaacgt tttcgtaatg gttcctctgt
      541 tgttttggag gatgaagatt actctcttat ttataatttt ctggttaatg caggttgcca
      601 acaagtcgaa ttagccgaac aagtggatgc gatagtaagt gcgaatctgg ccgcagatag
      661 tgatattacc gaagaaaaga tttgcgagaa atataaatcg accattgagg cgtttaaaaa
      721 aaagcaacta gcgttaccag tatgagttcg gcgtaagaac tcagaggctt aattccccta
      781 tcccatagat aacgataggg gaaaattatt tttgcagaat ttatgttatt gccattattt
      841 gagcaacttt tgcagcaggt ccatcacttg ctgtacctct tccggtgtga gcgccccgtc
      901 tttggcccat tgcacgcgac cgtctttatc cagcaccact acagcggaac tttcttcatc
      961 cagctgccag gcaccgcgcg cgacgccatt gctatcgaca ataaactgcg accagggata
     1021 aagcttttta ttactctcca gactgctgcg cacaaacatc cctgaacccg gaatcgcgtc
     1081 gtcggtgtta acaatggtgg tggtctggta acgatcgtgc ggtaacttcg ctgctttaat
     1141 cgcttcaatc agcgtcgcgt ttttctcttt tgcagaggtg cgaccagcaa tatgttgcag
     1201 tactcgcact tttcccacta actgcgcgct gttccaggtt ttgtagctaa actgatcttt
     1261 atcaagcacc aactcgccac gatcggtaat gccaatcggc ggcactcgct gaccggtttc
     1321 gaactgatgt gcggaagcca tcatcggcaa cagcaggcag gtgagtgcca gaatcttgcg
     1381 tagggtcatg gtgtttcctt cttatgatat gcaggtgatc cgaccacttg ggtctgagtt
     1441 ttaatcatat gtgctattta tcgaatttcc cgcaagtgtg atgccagttt gcggtcaagc
     1501 gcacaaatca tatgaaaaat gaatgcttat actgaagacc gcgcttcggt aaaaagataa
     1561 ttctgaataa ttgtaacctt taggtaaaaa aagttatacg cggtggaaac attgcccgga
     1621 tagtctatag tcactaggca ttaaaatttg cgcctcataa tagttgggcc gattgtggca
     1681 ccgcaaaggc gtaatactca gcaggagata acaatgaaaa ttttccaacg gtacaaccca
     1741 cttcaggtgg cgaagtacgt aaagatcctg ttccgtggac ggttatacat caaggacgtt
     1801 ggcgcttttg aatttgataa gggtaagatt cttatcccaa aagtgaagga taagctgcat
     1861 ttgtcagtga tgtccgaagt taaccgtcag gttatgcgtc tgcaaacaga gatggcttaa
     1921 ccaaagtgct atgcagtaat aagacggctc ctgattcagg agccgttgat gtttctgggg
     1981 gttacgcgac gctttcttct ttatctttag cgtcaggcag ttttggcgaa agggcggtgg
     2041 ccttgctgtc gattcgggtc accagcagct ggtcgatgcg gtagttatcg atatccacca
     2101 cttcaaattt gtagccggcg aatttcaccg aatcggtgcg tttcgggatc ttacgcagca
     2161 taaacatcat aaagccgccg atggtttcgt agttgcccga ctgcgggaac tcgtcaatat
     2221 ccagcacgcg catgacgtcg tcaatcggag tgccgccgtc aatcagccat gagttctcat
     2281 cacgggcgac aatctgctct tccagcccct gaccgaccag atcgcccatc agcgtggtca
     2341 tcacgtcgtt gagggtgatg atccccacca ccagcgcgta ctcgttcatg atcaccgcga
     2401 agtcttcacc tgcggtttta aaactttcca acgcctctga aagggttaac gtatccggca
     2461 caatcagcgt gttgcggatt tgtacgccgc tgttcagtgc caggctttgg ttagccagca
     2521 cgcggttcag caggtcttta gaatcgacat agccgatgat gtggtcaata tcttcattac
     2581 agacgaggaa cttagagtgc ggatgttccg ccaccttatt cttcagactt tgctcatctt
     2641 cgtggagatc aaaccaaatc acgttttcac gcggtgtcat tgacgacgga acggtacggg
     2701 attccagctc aaagacgttt tcaatcagct cgtgttcctg tttacgtaac acgcccgcca
     2761 gcgcaccggc ttccactacc gcgtagatgt catcagaagt gatgtcatct ttacgtacca
     2821 ttggcagttt gaaaatacgg aagatcatgt tcgccaggcc gttgaagaac cacaccagcg
     2881 gggtgcaaac gtacaggcag aagcgcatcg ggttgatgat acgcaaagcc actgcttctg
     2941 gcgcaatcat accgatgcgt ttcggggtta aatccgcaaa caggataaac atgccagtca
     3001 ctaacgagaa agagagaata aagctcagtt gctcagagag ttctgccgac atatagcggg
     3061 agaacaggct gtgaaaagct ggagaaaatg ccgcatcacc gacgataccg ccgagaatcg
     3121 ccactgcgtt cagaccgatt tggaccacgg taaagaacat gccgggattt tcctgcatat
     3181 tcagaacgcg ttgggcattt atattgcctt catcagccag cagtttaagt ttgattttgc
     3241 gtgaagcggc aagcgagatc tcggacatcg agaagaacgc acttacagcg atcaaacaga
     3301 gtatgactaa aatactgttt aacatatctt atccgacctt tcaggccaga tcctcggaag
     3361 gggaagttga ttaatttgtg tgaaatacac attgaaagcc gattcgaaga aagtgaaccg
     3421 gcattttcag tggctagtat agcgtaaggt actgtaaagc cgccagaggg ttaaaattca
     3481 gactgctgat aaatgaaaaa ctggctgatg cgctatgccg atcaggccta cgcagtccac
     3541 gcaatatatt gattttggac gattttgtag gcctggcaag gcgtttacgc cgcatccggc
     3601 atagacaaat agcactttat caacaatcta catttgtacc cgtaacgcta tgcttccggc
     3661 ggcagacaga cgccaattcc gccaattcca cagtaaccat acgggttttt atgcagatat
     3721 tgctggtggt catcttcggc ataataaaac ggtgtggcgt tcgcgatttc cgtggtgatg
     3781 cgacgatcgt catcggcggc aagcatcgcc gcctgaaaac gttccagact ggcgcgagct
     3841 gcggcatcct gttctggggt cagcggataa atcgctgaac gatactgcgt gccgtggtca
     3901 ttgccctgac gcattccctg ggcgggatcg tgattctccc aaaatacttg tagcaactgt
     3961 tcatagctga tgacggaagg atcgtaaaca atgcgtaccg cttcggcatg acccgtatca
     4021 ccggagcaca cttcccgata agtcggattt ggcgtatagc cgccggtata gcctgcggcg
     4081 gtgctgtaaa cgccgggtaa ctgccagaac agtcgctcca caccccagaa acaacccatc
     4141 gcaaaaatgg caatctccat tccgtcaggt acattggtca ttgagtgacc gttgaccgca
     4201 tggagcgtgg ctacgggcat cggggtgtta cgtccaggca gggcatcggc gggggaaacc
     4261 agatgctttt tatcaaataa actcatggtg tcgctctccc gaaaatcggt cattggggtt
     4321 aaggttgtaa caagaggcgt atttgcacac aataaccgcc gtgaataggt ctaaagtaaa
     4381 acataagaaa tatttggggt ttagtctgct ttttaatcca tattactgga tttttgttaa
     4441 gccgtttaac ggcgttccag gggcaggaaa aaaggatatt caggagaaaa tgtgcgctat
     4501 atccgacagt tatgctgtgt aagcttactc tgcttaagcg gatctaccgt cgccgcgaac
     4561 gtccgtctac aggtcgaggg gttatcggga cagctggaaa agaacgttcg tgcgcagctt
     4621 tctacgattg aaagtgatga agtgacgcca gaccgtcgct ttcgcgcacg cgtcgatgat
     4681 gccatccgcg aaggtctgaa agcgctgggt tattaccagc cgaccattga atttgatctc
     4741 cgtccaccgc caaagaaagg gcggcaggta ttgatcgcca aagtcacgcc aggcgtgccg
     4801 gtgttaattg gcggcaccga tgtggtattg cgcggcggcg cgcggaccga taaagactat
     4861 ttgaaattgc tcgatactcg cccggctatt ggtacggtac tgaaccaggg cgattatgaa
     4921 aatttcaaaa agtccttaac cagcattgcg ttgcgtaaag gttatttcga tagcgaattt
     4981 accaaagcgc agctgggcat tgcgctcggc ctgcataaag ccttctggga tattgattat
     5041 aacagtggcg aacgttaccg ctttgggcat gtgacctttg aaggatcaca aatccgcgat
     5101 gaatacctgc aaaatctggt gccgtttaaa gagggcgatg agtacgaatc gaaagatctg
     5161 gcagaactga accgccgact ttctgctacc ggctggttta actcggtggt ggtggctcca
     5221 caatttgata aagcgcgcga aacgaaagta ttaccattga cgggcgtggt ttcgccgcgc
     5281 acagaaaaca ccatcgaaac cggggtcggt tactctacgg acgtagggcc acgtgttaag
     5341 gcaacgtgga aaaaaccatg gatgaactcg tacggtcata gcctgaccac cagtaccagt
     5401 atttccgcgc cggaacagac cctcgacttc agctataaaa tgccactgct gaagaatcca
     5461 ctggaacaat attatctggt gcagggcggt tttaagcgca ctgacctgaa cgataccgag
     5521 tctgactcca ctacgctggt ggcttctcgc tactgggatc tctccagcgg ctggcagcgt
     5581 gccattaacc tgcgctggag tctcgaccac tttacccagg gtgaaattac caacaccacg
     5641 atgctgtttt atcctggggt gatgattagc cgcacgcgtt ctcgcggtgg cctgatgcca
     5701 acctggggcg actcgcaacg ctactctatc gactactcca acacggcctg gggctcagat
     5761 gtcgatttct ccgttttcca ggcgcagaac gtctggatcc gcacactgta cgatcgccat
     5821 cgttttgtta cacgcggcac gctgggctgg attgaaaccg gtgatttcga caaagtaccg
     5881 ccggatctgc gtttcttcgc cgggggcgat cgcagtattc gcggctacaa atacaaatca
     5941 atcgctccga aatacgccaa cggtgacctg aaaggggcct cgaagttgat aaccggatcg
     6001 ctggagtacc agtacaacgt gaccggaaaa tggtggggcg cggtgtttgt cgatagcggc
     6061 gaagcggtaa gcgatattcg ccgcagcgac tttaaaaccg gtaccggggt cggcgtgcgc
     6121 tgggaatcgc cggtcgggcc aatcaaactc gattttgccg taccggtcgc ggataaagac
     6181 gaacacgggt tacagtttta catcggtctg gggccagaat tatgagttta tggaaaaaaa
     6241 tcagcctcgg cgtggttatc gttatcttgc tgttgctggg atcggtggcg tttctggtgg
     6301 gcaccaccag cggcctgcat ctggtattta aagcggcgga tcgctgggtg ccaggactgg
     6361 atattggcaa agtcaccggc ggctggcgcg atctcacctt gtctgacgtt cgttatgagc
     6421 agccaggcgt ggcggtaaaa gcgggcaatc tgcatctggc ggtcgggctt gagtgcctgt
     6481 ggaacagtag cgtttgtatt aatgacctgg cgctgaaaga cattcaggtc aacatcgaca
     6541 gtaaaaaaat gcctccttct gaacaggttg aagaagagga agatagcggc ccgctggatc
     6601 tctccacgcc gtatcccatc accctgacac gggtggcgct ggacaacgtc aacatcaaga
     6661 ttgatgacac cacggtatcg gtgatggact tcacctccgg cctgaactgg caggagaaaa
     6721 ccctgaccct gaaaccgacg tcgctgaaag gcctgttgat tgctttgccg aaagtggcgg
     6781 aagtggcgca ggaagaagtt gtcgaaccga aaattgaaaa tccgcagccg gatgaaaagc
     6841 cgctcggcga aacgctgaaa gatctctttt ctcgcccggt attgccggaa atgaccgacg
     6901 tgcatctgcc gctcaacctg aacattgaag agtttaaggg cgagcaactg cgcgtgacgg
     6961 gcgacacaga catcaccgtg cgcaccatgc tgctgaaagt gagcagcatc gacggcaata
     7021 ccaaactgga cgcgctggat atcgactcca accaggggat tgtcaacgcc agcggcacgg
     7081 cgcagctgtc agacaactgg ccggtggata tcaccctcaa cagcacactg aacgtggagc
     7141 cgttgaaagg tgaaaaggtg aagctgaaag tgggcggcgc gctgcgcgaa cagctggaga
     7201 taggcgttaa cctttctggt ccggtggata tggatttacg cgcccagacg cgactggcgg
     7261 aagccggatt gccgctcaac gtggaagtga acagcaaaca gctttactgg ccgttcactg
     7321 gagagaagca gtatcaggcg gatgatctga aactgaaact taccggcaaa atgaccgatt
     7381 acacgctctc tatgcgcacg gcagtgaagg gacaggagat cccgccagcc accattaccc
     7441 ttgatgccaa aggtaatgaa cagcaggtca atctcgacaa actcaccgtc gcggcgctgg
     7501 aagggaaaac tgaactcaaa gcgttgctcg actggcagca ggccattagt tggcgcggtg
     7561 agctaacgct taacggcatt aacaccgcca aagagttccc ggagtggccg tcgaaactca
     7621 atggcttgat taaaacccgc ggtagcctgt acggcggcac ctggcagatg gaggtgccag
     7681 aactgaagct gaccggtaac gtcaaacaga acaaagtgaa cgttgacggc acgctgaaag
     7741 gcaacagtta tatgcagtgg aagatcccag ggctgcatct ggaactgggg ccaaacagtg
     7801 ccgaagtgaa aggcgagctg ggggtaaaag atctcaatct tgatgccacc atcaacgcgc
     7861 cggggctgga taacgcgctg ccggggcttg gcggtacagc gaaagggctg gtgaaagtac
     7921 gcggcacggt ggaagcgcca caactactgg cagatatcac cgcgcgcggc ctgcgctggc
     7981 aggaactttc cgtggcgcag gttcgcgtgg aaggcgatat caaatccacc gatcagattg
     8041 cgggtaaact tgacgtacgc gttgagcaaa tctcgcagcc cgatgtgagt atcaacctcg
     8101 tcaccctgaa tgccaaaggt agcgaaaaac agcacgagct acagttgcgg attcagggcg
     8161 aaccggtttc cggacagctt aatctgacag gaagttttga tcgcaaagaa gaacgctgga
     8221 agggaacgct tagcaatacc cgcttccaga cgccagtcgg cccgtggtcg ctgacccgcg
     8281 atattgcgct ggattatcgc aacaaggagc aaaaaatcag catcgggcca cactgctggc
     8341 ttaacccgaa tgcggaactg tgcgtgccgc aaactatcga tgcgggggcc gaagggcgtg
     8401 cggtggtgaa tctcaaccgc ttcgacctgg cgatgctgaa accgtttatg ccagaaacca
     8461 ctcaggccag cggtatcttc acgggtaaag cggatgtcgc ctgggacacc acgaaagagg
     8521 ggctgccgca gggcagtatc accctttcgg ggcgtaacgt gcaggtaacg caaaccgtca
     8581 acgatgcggc gctgcccgtg gcgtttcaga cgctgaatct gacggcggag ttgcgtaaca
     8641 accgtgccga attgggctgg accatccgcc tgaccaataa cggccagttt gatggacagg
     8701 tgcaggtggc cgatccgcaa ggccgccgta atcttggtgg caacgtcaat atccgtaact
     8761 tcaaccttgc gatgataaac cccatcttta cccgtgggga aaaagctgcg gggatggtga
     8821 gtgccaactt acgtctgggt ggtgatgtgc aaagcccgca gttgtttggg cagctacagg
     8881 ttacgggtgt ggatatcgac ggcaacttta tgccgtttga tatgcagccg agccagcttg
     8941 cggtcaactt taacggtatg cgctcgacgc ttgccggtac agtacggacc cagcagggtg
     9001 agatctacct gaacggcgac gccgactgga gccagattga aaactggcgg gcgcgggtaa
     9061 cagcgaaggg cagtaaagtg cgtatcaccg tgccgccgat ggtacgaatg gatgtatcac
     9121 cagatgttgt atttgaggct acaccaaacc tgtttaccct tgatggtcgc gtggatgtcc
     9181 cgtgggcgcg catcgtggtg cacgatctgc cggaaagcgc ggtgggcgtc tccagcgatg
     9241 tggtgatgct taacgataac ctgcaaccgg aagaggcaaa aacggcgtcg attccgatta
     9301 acagcaacct gattgtccac gtcggcaaca atgtgcgcat tgacgccttt ggcctgaaag
     9361 cgcggctgac gggcgatctc aacgtcgttc aggacaaaca agggctgggc ctgaacgggc
     9421 agatcaacat ccctgaaggg cgcttccatg cctatggtca ggatctgatt gtgcgtaagg
     9481 gtgagttact gttctctggt ccgccggatc aaccgtatct taatatcgaa gctattcgta
     9541 acccggatgc tacagaagac gacgtaatcg ccggagttcg cgtcactggt ctggcggacg
     9601 aaccgaaagc ggagatcttc tctgacccgg ccatgtcgca acaggctgcc ttgtcttatt
     9661 tgctacgtgg acaagggctg gagagcgatc agagcgacag tgcggcgatg acctcaatgc
     9721 tgattggtct gggggttgca caaagtggtc agattgtggg taaaatcggc gagacgtttg
     9781 gcgtaagcaa tttagcgctc gacacccagg gagtaggcga ctcctcccag gtggtggtca
     9841 gcggctatgt attgccaggt ctgcaagtga aatacggcgt gggtatattt gactctatag
     9901 caacactcac gttacgttat cgcctgatgc ctaagctata tctggaagcc gtgtctggtg
     9961 tagaccaggc actggatttg ctctatcagt tcgagtttta gcaatgcgaa tatttgtcta
    10021 cggcagttta cgccacaaac aaggcaacag tcactggatg accaatgccc agttactggg
    10081 cgatttcagt atcgataact accagttgta tagcctgggc cactatccag gcgcagttcc
    10141 ggggaacgga acagtacacg gtgaagttta tcgtattgac aacgccacgc tggccgaact
    10201 tgatgccttg cgcaccaggg gcggtgaata cgcgcgccag ttgattcaga cgccgtacgg
    10261 gagtgcatgg atgtacgttt atcaacgacc cgtcgatgga ttaaagctaa ttgaaagcgg
    10321 cgactggtta gacagggata agtaaccata cgcatacgcc accttcgggt ggcgttgttt
    10381 tttgcgagac gactcgcatt ctgttttgta attccctcac cttttgcttt tctctccgag
    10441 ccgctttcca tatctgttaa cgcataaaaa actctgctgg cgttcacaaa tgcgcagggg
    10501 taaaacgttt cctgtagcac cgtgagttat actttgtata acttaaggag gtgcagatgc
    10561 gtattaccat aaaaagatgg gggaacagtt caggtatggt cattcctaat gttgtgatga
    10621 aagaacttaa cttacggccg gggcagagcg tggaggcgca agtgagcaac aatcaactga
    10681 ttctgacacc catttccagg cgctactcgc ttgatgaact gctggcacag tgtgacatga
    10741 acgccacgga acttagcgag caggatgtct ggggtaaatc cacccctgcg ggtgacgaaa
    10801 tatggtaaag aaaagtgaat ttgaacgggg agacattgtg ctggttggct ttgatccagc
    10861 aagcggccat gaacagcaag gtgctggtcg acctgcgctt gtgctctccg ttcaagcctt
    10921 taatcaactg ggaatgacgc tggtggcccc cattacgcag ggcggaaatt ttgcccgtta
    10981 tgccggattt agcgttcctt tacattgcga agaaggcgat gtgcacggcg tggtgctggt
    11041 gaatcaggtg cggatgatgg atctacgcgc ccggctggca aagcgtattg gtctggctgc
    11101 gggtgaggtg gtggaagagg cgttattacg tttgcaggcg gtggtggaat aaggtgtgtt
    11161 tatttatcgc gggcataaaa aacccctact aaccgaagcc cggcgttcag ggttattacg
    11221 ctagaagaac ttatttattc tttgcgcgct cgaaggaggc aacgatttca gctttagcgg
    11281 cttctgcgtt ttcccagcct tcaactttca cccacttgcc tttttcgagg tctttgtagt
    11341 gctcgaagaa gtgagcgatc tgtgctttca gcagttcagg cagatcgtta acgtctttaa
    11401 tgtgatcgta ttctttgctc agcttgctgt gcggaaccgc aaccagtttc gcatcttcac
    11461 cggcttcgtc ggtcattttc agaacgccaa caggacggca acggatcaca gaacccggct
    11521 gcagcgggta cggagtcggg accagtacgt caaccgggtc accgtccaga gacagggtgt
    11581 ggttgatgta accgtagttg cacggataga acattgcggt ggacatgaag cggtcaacga
    11641 acagtgcgcc gctctctttg tcgatttcgt atttgatcgg atctgcgtta gccgggatct
    11701 caataacaac gtagatgtct tccggcagat ctttacccgc agggacgttg agtaagctca
    11761 tgtctgtttc ctttaaaaat atgtggcaaa caagtgccga gtattatagc caactcgcgc
    11821 cgaatgtctt cgcttgtttt cttcttcatt ttccttttta gccagtttta agatggttta
    11881 aagagcagga aaatccataa ccgtagccgc atttttcata gtgagatgaa agcgattaca
    11941 aacttgtgat taacgtttta tttacttttt tgaagtgtga tgtaacgcaa tccgttacat
    12001 aacgaattgt ctatagtttt ttcgcgaaca tcttttcacc aataataatt accccgacga
    12061 ggacaaccct atgtggaaac gcttacttgt agtctctgca gtctcggcag ccatgtcgtc
    12121 tatggcgttg gccgctccat taaccgttgg attttcgcag gtcggatcgg aatccggctg
    12181 gcgcgccgca gaaaccaatg tggcgaaaag tgaagccgaa aagcgcggaa ttacgttgaa
    12241 aattgccgat ggtcagcaaa agcaggaaaa ccagattaaa gcggtacgtt ccttcgtcgc
    12301 gcaaggggtg gatgcgatct ttatcgctcc ggtggtagcg acgggttggg agccggtatt
    12361 aaaagaggcg aaagatgccg aaatcccggt cttcttgctt gaccgttcca tcgatgtgaa
    12421 agacaaatct ctctatatga ccactgtcac cgccgacaac atcctcgaag gcaagttgat
    12481 tggtgactgg ctggtaaaag aagtgaatgg caaaccatgc aacgtggtgg agctgcaggg
    12541 caccgttggg gccagcgtcg ccattgaccg taagaaaggc tttgccgaag ccattaagaa
    12601 tgcgccaaat atcaaaatta tccgctcgca gtcaggtgac ttcacccgca gcaaaggcaa
    12661 agaagtgatg gagagcttta tcaaagcgga aaacaacggc aaaaacatct gcatggttta
    12721 cgcccataac gatgacatgg tgattggtgc aattcaggca attaaagaag cgggcctgaa
    12781 accgggcaaa gatatcctga caggctctat cgacggcgtg ccggacatct acaaagcgat
    12841 gattgatggc gaagcgaacg ccagcgttga actgacgccg aacatggcag gccccgcttt
    12901 tgatgcgctg gagaaatata aaaaagacgg caccatgcct gaaaagctga ccctgaccaa
    12961 gtccaccctt tacctgcctg ataccgcaaa agaagagtta gagaagaaga aaaacatggg
    13021 gtattgaggg ttgctatgcc tgatgccgat tcgtaggccg gataaggcgc tcgcgccgca
    13081 tccggcgatg gtgcactgaa gcctgatgcg acgcttaccg cgtcttatca tgcctactgg
    13141 gagcacgctt tacaccgggg gaaaccatga cgaccgacca acaccaggaa atcctccgca
    13201 ccgaaggatt aagtaaattt ttccccggcg tcaaagcgtt agataacgtt aatttcagcc
    13261 tgcgccgtgg cgaaatcatg gcgctgctcg gtgaaaatgg ggcgggaaaa tcgacgctaa
    13321 tcaaagcatt aaccggtgtt taccacgccg attgtggcac catctggctg gaaggccaga
    13381 ctatctcacc gaaaaatacc gcccatgcac aacaactcgg catcggcacc gtctatcagg
    13441 aagtcaacct gctacccaat atgtcggtcg ctgataatct attcataggt cgcgaaccca
    13501 aacgtttcgg ccttctacgc cgtaaagaga tggaaaagcg cgccaccgaa ctgatggcat
    13561 cttacggttt ctccctcgac gtgcgggaac cgctcaaccg cttttcagtc gcgatgcagc
    13621 aaatcgtcgc catttgccgg gctatcgatc tctccgccaa agtgctgatc ctcgatgaac
    13681 ccaccgccag cctcgacact caggaagtag agttactgtt tggcctgatg tgtcagttgc
    13741 gcgatcgcgg cgtcagcctg atcttcgtta ctcactttct cgatcaggtc tatcaggtca
    13801 gcgatcggat caccgtctta cgcaacggca gtttcgtagg ctgtcgggaa acgcgcgagc
    13861 taccgcagat cgaactggta aaaatgatgc tggggcgcga gctggatacc cacgcgctac
    13921 agcgtgccgg gcgaacattg ttgagcgaca aacccgttgc cgcgttcaaa aattacggca
    13981 aaaaaggaac gatcgcaccg tttgatctcg aagtgcgccc cggcgagatc gtcggcctgg
    14041 caggcttgct gggatcagga cgtaccgaaa ccgccgaagt gatcttcggg atcaaacctg
    14101 ctgacagcgg cacggcgttg atcaaaggca aacagcaaac cctgcgatcg ccacatcagg
    14161 cttcggtact gggtatcggc ttctgcccgg aagacaggaa aaccgatggc atcatcgccg
    14221 ccgcctcggt gcgggaaaat atcatcctcg ctctccaggc ccagcgcggc tggctacgac
    14281 cgatttcccg caaagaacag caagagattg cccaacgctt tatccgccag cttggcattc
    14341 gcacaccttc aactgaacaa ccgattgaat ttctctccgg cggcaatcag caaaaagtgt
    14401 tgctttcacg ttggctactg actcgaccgc aatttctgat cctcgacgag ccaacccgcg
    14461 gcattgatgt tggtgcgcat gccgagatca tccgcctgat tgaaacgctg tgcgccgatg
    14521 gtctggcgct gctggtgatc tcttccgaac tggaagagct ggtgggctat gccgaccggg
    14581 tgattatcat gcgcgatcgc aaacaggtgg cggagatccc gctggcagag ctttccgttc
    14641 cggcgatcat gaacgccatt gcggcgtaag gagaacagtg tgatgcctca atctctcccg
    14701 gacactacgc ctccgaaaag gcgttttcgc tggccaacag gaatgccgca gctggcggca
    14761 ctgttgctgg tgctgctggt cgatagcctg gtggccccgc atttctggca ggtggtgctt
    14821 caggatgggc gtttgttcgg aagccctatc gacattctta accgtgcggc ccccgttgcg
    14881 ctactggcga ttggcatgac gctggttatc gccactggtg ggattgatct ctccgtaggg
    14941 gcggtgatgg ctatcgccgg agccacaacg gctgcgatga cggtcgcggg attcagcctg
    15001 ccaattgttt tgttaagcgc cctgggcact ggcatcctgg caggattgtg gaacggcata
    15061 ctggtagcga tcctcaaaat tcagccgttt gtcgccaccc tgatcctgat ggtcgccggg
    15121 cgcggtgtgg cgcaactgat cacctccgga cagatcgtca catttaactc accggatctc
    15181 tcctggttcg gcagtggatc gctgttgttc ctgccaacac cagtcattat tgcggtactg
    15241 acgcttctcc tgttctggct gttgacccgc aaaacggcac tggggatgtt tatcgaagcc
    15301 gttggtatca acatgcgggc ggcaaaaaat gccggggtaa acacgcggat catcgtcatg
    15361 ttcacctacg tgttgagcgg gctgtgtgcg gcgattgcgg gcattatcgt ggcggcggat
    15421 attcgcggtg ccgatgccaa caacgccgga ttatggctgg agctggacgc cattctcgcg
    15481 gtggtgattg gcggtggttc gctgatgggc ggacgtttta acctactgct ttcggtggtg
    15541 ggggcgctga ttattcaggg gatgaacacc ggaattttgc tttcgggctt tccgccggag
    15601 atgaaccagg tggtgaaagc ggtggtggtg ctttgcgtgc tgattgtcca gtcgcaacgc
    15661 tttatcagtc tgattaaagg agtgcgtagc cgtgataaaa cgtaatttgc cactgatgat
    15721 caccatcggc gtctttgtgc tgggttattt ctactgcctg acgcagtttc ccggttttgc
    15781 ttccacaaga gtgatctgca atatcctgac cgataatgcc tttcttggga taatcgccgt
    15841 tggcatgacc tttgtgatcc tctccggtgg gatcgatctc tccgtcggtt cggtgatcgc
    15901 ctttaccggc gtgtttctgg caaaagtgat tggcgatttc ggcctctcgc cgttgctggc
    15961 gtttccactg gtgctggtga tgggctgtgc ctttggcgca tttatggggc ttttgatcga
    16021 cgccctgaag atcccggcgt ttatcattac tctggcagga atgttctttt tgcgtggcgt
    16081 cagctatctc gtttcggaag agtcgatccc gataaatcat cctgtttatg acacgctctc
    16141 aagccttgca tggaaaatcc ctggcggcgg tcgtttaagt gcgatggggc tgctgatgct
    16201 ggcggtggtg gttatcggca tattcctcgc gcatcgtacc cgttttggta atcaggtata
    16261 cgccattggc ggcaacgcaa cgtcggcgaa cctgatgggg atttccactc gcagcaccac
    16321 tattcgcatt tatatgcttt ccaccggact ggcaacgctg gcggggattg tcttctcgat
    16381 ttatacccag gccggatatg cgctggcggg cgtaggtgtg gaactggacg ctatcgcctc
    16441 agtggtgatt ggcggtacgc ttttgagcgg tggcgttgga acggtattag ggacgctttt
    16501 tggcgtggcg attcagggac tgattcagac ttacataaac tttgatggca cgctgagctc
    16561 atggtggacg aaaatcgcca tcggtatttt gttgtttatt tttatagcat tacagcgtgg
    16621 attaacggtg ctgtgggaga atcgtcagag ttcgcctgtg acaagagtca acattgcgca
    16681 gcgataaaaa cgcctctccg tgtggagagg cgcaggagat tacgcgtccg ggaactcacg
    16741 gataaagcgt tcgacatctt caaccatatg gtcgttgccg acaaagaacg aacggcgctg
    16801 gtgcagggtt tccgggatga tatccagaat acgctctttg ccatcgctcg ctttaccgcc
    16861 cgcttgttcc gccaggaatg ccatcgggtt gcactcatac agcaaacgca gtttaccgtc
    16921 cgggtggctg gcggtgcttg ggtagagata aatcccacct ttcagcaggt tacggtggaa
    16981 atccgcaacc agtgagccga tataacgcga ggtatacggg cgattggtgg acttatcttc
    17041 ttcctggcag aatttaatgt acttcttcac cccgttcgga aacttaatgt agtttccttc
    17101 gttgatggag taggttttgc ctttctccgg gaagcgcatc cgttcctggc acaggcagaa
    17161 aacgccgagc gaaggatcgt aagtaaaggc gtgaacaccg catccggtgg tgtaaaccag
    17221 catggtagag gagccgtata ccacgtaacc tgcggcaacc tgtttgttac caggctggag
    17281 gaaatcttct tccgttaccg gcgtgccaac aggcgtaacg cggcggtaga tggagaaaat
    17341 ggtaccgaca gagacgttaa catcgatgtt ggacgagcca tccagggggt ccatcagcac
    17401 cacgtatttt gcgtgttcac agccttcaaa gacgacaatc tcatcttctt cttcagaggc
    17461 aatgcccgca acgatatcgc gtgctttcag tgcggctttc agtttttcat tagcgaacaa
    17521 gtcgagtttc tgctgaacct cgccctgcac gttctcagca ccgctggcac ccagaatatc
    17581 aaccagtcct gctttgttga tatcgcgatg gataatcttg gcgcccagtt ttattgccga
    17641 cagcaaagca gtgagctcac cggtagcatg agaaaactcg tgctgctttt cgacaataaa
    17701 ttcacctaac gttttcataa aactttccct gcaatgttta tggagtaaag cgaccgcaac
    17761 aatcttaaca aataatctca atgttgcgct caggtgaatc gcgccagcaa attgcggatt
    17821 atcctgaaat gcgtttctca cttgcccgac atatgcgtaa aatgagcggc agattaaaaa
    17881 aggatagtga cgtatgcgca ttcatatttt aggaatttgt ggcacgttta tgggcggtct
    17941 ggcgatgctg gcgcgccagt taggccatga agtaacgggt tcggacgcca atgtgtatcc
    18001 gccgatgagc accttacttg agaagcaagg cattgaactg attcagggtt acgatgccag
    18061 ccagctcgac ccgcagccgg atctggtgat tattggcaac gccatgaccc gtggaaatcc
    18121 gtgtgtggaa gcggtactgg aaaaaaacat cccttatatg tcaggtccgc agtggctgca
    18181 cgattttgtg ctgcgtgacc gttgggtgct ggccgtcgcc ggtacacacg gtaaaacgac
    18241 tacagcggga atggcgacct ggattctgga acagtgcggt tacaaaccag gatttgtgat
    18301 cggcggtgtg ccggggaact ttgaggtctc ggcgcgtctg ggcgaaagcg acttctttgt
    18361 tatcgaagcg gatgagtatg actgcgcctt cttcgacaaa cgctctaaat ttgtccatta
    18421 ctgcccgcgt acgctgatcc tcaacaacct tgagttcgat cacgccgata tctttgacga
    18481 cctgaaagcg atccagaaac agttccacca tctggtgcgt atcgttccgg ggcagggccg
    18541 tattatctgg ccggaaaacg acatcaacct gaaacagacc atggcgatgg gctgctggag
    18601 cgagcaggag ctggtgggcg agcagggtca ctggcaggcg aaaaagctaa ccaccgatgc
    18661 ttctgaatgg gaagtcttgc tggatggcga aaaagtgggc gaagtgaaat ggtcgctggt
    18721 aggcgaacat aatatgcata atggcctgat ggcgattgcg gcggcccgcc atgttggcgt
    18781 agcgccggca gatgccgcta acgcgctggg ttcgtttatt aatgctcgtc gccgtctgga
    18841 gttgcgtggt gaagcgaatg gtgtgacggt atatgacgat ttcgcccatc acccgacggc
    18901 gattctggca acgctggcgg cgctgcgtgg caaagttggt ggtacggcgc gcattattgc
    18961 tgtgctggag ccgcgctcga ataccatgaa aatggggatc tgcaaagacg atctggcacc
    19021 ttcattaggt cgtgccgatg aagtcttcct gctgcaaccg gcgcatattc cgtggcaggt
    19081 ggcagaagtg gcagaagcct gcgttcagcc tgcacactgg agtggcgatg tggatacgct
    19141 ggcagatatg gtggtgaaaa ccgctcagcc tggcgaccat attctggtga tgagcaacgg
    19201 cggttttggt gggatccatc agaaactgct ggatgggctg gcgaagaagg cggaagccgc
    19261 gcagtaattc ggccttagcc agatatagta tgcgtaggcc ggataaggcg ttcacgccgc
    19321 atccggcatt tgagcatagt gcctgatgcg acgcttgatg cgtcttatca ggcctacagg
    19381 tgcaccgtat ccggcaaacc atactcacat caacaacgaa aattaccctt cgttctccgc
    19441 taactcgcgc agatactgga aaatctggcg tgcggatttc ggcggcttat tcccttcttt
    19501 ctctttcttc gcgttgcgga tcagagtacg cagttgctga cgatcggcat cgggccacag
    19561 atttaatacc tcagcgatgg cgtcatcacc ttgatcgatc agacgatcgc gcaggttttc
    19621 cagtttatgg aacagcacca cctgctggtt gtgacggttt ttcagcttat ccagcgcctg
    19681 acgaataggc tctacgtcgc gctggcgcag catcttaccg atgagctgca actggcggcg
    19741 gcgaccttcc atcttaatac gctgggcgag ctcaatagcc gcgcgcagat ccgcatctaa
    19801 cgggatctta tccagcgcgt ttttccccag atcaacaatt tccgcgccaa ggcgttttag
    19861 ctcctcggca tcacgtttaa tttcactttt actgacccag ataatttcat cgtcttcgtc
    19921 ttcgatgtca tcaccgggaa cgtcgtcgag ccagtcttcg ggctgcttag tcatctcagg
    19981 ctccttaaaa aaagaggcta atgttaccag ttaagatgcg cactgaaaaa cggttctctg
    20041 ttagacttca gagaaactct ctacattatg gcacttgcaa tgaaagtaat ctctcaagtt
    20101 gaagcgcagc gcaagattct ggaagaagca gtttccactg cgctggagtt ggcctcaggc
    20161 aaatcggacg gtgcggaagt tgccgtcagc aagaccaccg gcattagcgt aagcacgcgt
    20221 tatggtgaag tggagaatgt tgaattcaat agcgatggcg cgctggggat cactgtttat
    20281 caccagaacc gcaaaggtag cgcatcatcc accgatttaa gcccgcaggc cattgcccgt
    20341 actgtacagg cggcgctgga tattgcccgt tatacctcgc cagatccctg tgccggcgtg
    20401 gcagacaaag agctgctggc ctttgacgca ccagatctcg acttgttcca ccctgcggaa
    20461 gtttccccgg atgaagccat tgaactggcg gcccgcgcag aacaggcggc attgcaggcg
    20521 gacaaacgca tcaccaatac cgaaggtggc agctttaaca gccactacgg tgtcaaagtt
    20581 tttggcaaca gccacggcat gttgcagggt tactgctcaa cgcgtcattc gctctccagc
    20641 tgtgtaattg ccgaagaaaa tggcgatatg gagcgtgatt acgcctacac cattggtcgt
    20701 gcgatgagcg atctgcaaac gccagagtgg gttggggccg actgtgctcg ccgtacttta
    20761 tcgcgtctgt caccgcgtaa actctccacc atgaaagcgc cagtcatttt tgccaatgaa
    20821 gtggcaaccg ggctttttgg gcatctggtg ggggcgatag cgggtggatc ggtttatcgt
    20881 aaatctacct tcctgctgga ttcgctgggt aaacaaattc tgccggactg gctgaccatt
    20941 gaagagcatc cgcatctgct gaaagggctg gcgtcgacgc cattcgacag cgaaggtgtg
    21001 cgcaccgagc gtcgcgatat tattaaagat ggcatcctga ctcagtggct gctgaccagc
    21061 tactcggcgc ggaaactggg gctgaaaagc accggacatg cgggcggtat tcacaactgg
    21121 cggattgccg gacaaggtct aagcttcgag cagatgctca aagagatggg caccgggctg
    21181 gtggtgacgg aattgatggg ccagggcgtg agtgccatta ccggtgatta ttcccgtggt
    21241 gcagcgggct tctgggtaga gaatggcgaa attcagtatc cggtgagcga aatcaccatc
    21301 gcaggtaatt taaaagatat gtggcgcaat attgtcaccg tcggtaacga tattgaaaca
    21361 cgcagtaata tacagtgtgg ttctgtgctg ttgccggaga tgaaaatcgc cggacagtaa
    21421 aaaaactggc gcgacctgcc gcgctataaa ctaaaaaatt acacaaaatc attcgcactg
    21481 catcgagacg gaaagtgaat gagggccggg gagcgtactc gcagtacgtg acccggtcga
    21541 atgagcgtag tcgtcgatga ggcagtgtga aggatgaagt gtaaataaaa aaggaagtga
    21601 gcaatgcgaa aaagcctgtt agctattctt gcagtctcct cgttggtatt cagttcggcg
    21661 tcatttgctg ctgatctcga agacaatatg gaaaccctca acgacaattt aaaagtggtc
    21721 gaaaaagccg ataacgcggc gcaagtcaaa gacgcgttaa cgaagatgcg cgccgcagcg
    21781 ctggatgcgc aaaaagcaac gccgccgaag ctcgaagata aatcaccgga cagcccggaa
    21841 atgaaagatt tccgccacgg tttcgacatt ctggtcggtc agattgacga cgcgctgaag
    21901 ctggcaaatg aaggtaaagt aaaagaagcg caggctgctg cagagcaact gaaaacgacc
    21961 cgcaattcat atcacaagaa gtatcgttaa ttcctcattt ccctgttgcc tgcactcagg
    22021 taacagggaa cttatcatcg caaatgatgc accacctgat tgctgctgcc gcgccagatc
    22081 agggaagggt cttttaaatc ctgcacaaat ttgccgtcga ccagcacgtt aatcaaatca
    22141 acaacctgca tttgcgcagc gttgagttcg tcgagtttat agcctgtcca cacccagatg
    22201 tctttacccg gacactcggc gcggatgcgt tgtaccagtt tcagaatatc cggcacgttt
    22261 tgcggatgca gcggatcgcc gccggagagg gaaataccct ggcgtttgat acgagtgtca
    22321 ttcagatcgt taatgatctg gtcttccatt gctttggtaa atggctgacc ggaatttacc
    22381 cgccatgtgc ttttgttata gcaaccgggg cattcatgaa cacacccgga gacaaacagg
    22441 gtgcaacgag tgccggggcc gttgacgatg tcgacaggat agtactgatg ataattcatt
    22501 atttcgcctg gcttatcagt ccgcgtgtag gctgcatccg gtaatcaatg cctgatgcga
    22561 cgctgtcgcg tcttatcaga cctggagcaa ttgccaaatg taggccggat aaggcgttta
    22621 cgccgcatcc ggcatttgct tagctcagag tgaagattaa cctatctgcc cattccccaa
    22681 atgtttaacg cggcgcttaa cttcttcctg cttaccagcg ttaaacggac gtgcatccgg
    22741 gctacctaaa tatccgcaca cgcggcgagt taccgacaca cgggaggcgt catggttacc
    22801 acatttcggg caagtgaagc ctttgctggt gcactcgaac tcaccggtaa agccacactc
    22861 gtagcactca tcaatcggtg tattggtgcc gtaatacggt acatgctgat agctgtaatc
    22921 ccagacatct tccagcgcct tcaggttgtg ctgaatgttt ggatactcgc cgtagcaaat
    22981 gaaaccaccg ttcgccagcg gcgggtaagg cgcttcaaag tcgatcttgt cgtacgggtt
    23041 caccttcttc tccacatcga ggtggaaact gttggtgtag taacctttat cggtcacgcc
    23101 cggcaccacg ccaaactcag cagtatcgag acggcagaag cgatcgcaca ggttttcact
    23161 cggcgtgctg tagagactga aaccataacc cgtttcttct ttccactgat ccactgcctg
    23221 acgcagacgt tcaacaatgg cgataccttt cgcgcgaagc tgctcgttgt cgtaaacatg
    23281 ctcgccgccg aacagcgcgt taatggtttc gtggatgccg atgtaaccca gcgaaataga
    23341 cgcacgaccg tttttgaaga tttcagaaac atcatcgtca gcattgagac gcacgccaca
    23401 agcaccttcc atatagagga tcggggccac gcgcgctttc acgccttcga gacgagcgat
    23461 acgggtcatc agcgccttac gtgccagcac cagacgttca tccagcagct tccagaaggt
    23521 ggcttcatcg ccttttgctt ccagagcaat acgcggcagg ttcaggctga tcacgccgag
    23581 gttgttacga ccatcgtgga tctgctcgcc gttttcattt tcccacacgc cgaggaagct
    23641 gcggcagccc atcggagttt taaacgaacc ggtgactttc actacctgat cgtagttcag
    23701 gatatccgga tacatgcgct tgcttgcgca ctccagcgcc agctgtttga tgtcgtagtt
    23761 cggatcgcct tttttatggt tcaggccatc gcgaatcgca aacaccagtt tcgggaacac
    23821 cgcagtttta cggtttttac cgaggcctgc gatacggtta cgcaggatcg attcctgaat
    23881 caggcgcgat tcccagctgg tgcccaggcc aaaaccaaag gttacaaacg gcgtctgacc
    23941 gttggcggtg tgcagggtgt ttacttcgta ctccagtgac tggaaggcat cgtagcactc
    24001 tttgatggtt cgagagttag cgtagccttc ggcgtccggg atgttccact cttctgcggt
    24061 cttgcgatgt ttgttgtagc tggcagtgac aaacggtgcc agcacttcat cgatacggtt
    24121 aatggtggtg ccgccataaa tatggctggc aacctgagca ataatctgcg cagttaccgc
    24181 ggttgccgta gagatcgact tcggcggttc aatctcggcg ttccccattt taaagccctg
    24241 ggtcagcatg cctttcaggt cgatcaacat gcagttgaac atcgggaaga acggtgagta
    24301 atcgagatcg tgatagtgaa tatcgccacg ctcatgtgcc tgcaccacgt cacgcggcag
    24361 caggtgctga cgtgcatagt gtttagccac gatcccggcc agcaggtcgc gctgggttgg
    24421 aatcaccttg ctgtctttgt tggcgttttc gttgagtaac gaggcgttgg tctgctcgac
    24481 cagaccacgg atctcctggt tcaggcgacc gcgtttttca cgttcaatgt cgcgatcgtg
    24541 acggtactcg atgtaagcac gagccagttg tttgtatgga cctgacatca gctgattttc
    24601 aactgcggtc tggatctcat tgatatccac ctggttgcgg ccctgcatct gctcgctgac
    24661 aaccgcggca acagtggcgc aataatcggc atcatcgact tccgctgctt tagctgcacg
    24721 cagaatcgct tctttgatgc gctctgattt aaacggcact ttgcagccgt ctcgtttcat
    24781 cacatgcggt gtcatgatcg ctccatattt ttaagaacag gttatccaca gaaattggga
    24841 aaggcgtttt ccggtttttt cgtttcgttt tccggtgctt tccgcaatcg ccatccgctt
    24901 atccacaacg ccgcaccttt ttcgtgggga gctgtagtag caattatagt cgattaatac
    24961 aacatattgg gttgggacgc attttaaagt ctatatatag tgctttgcat caaggatgtt
    25021 tgaacttttt ttgatgtagc tcaaagtaaa aagcagagcg tacggatgac gggcgctaca
    25081 gcgatatgta aattttttaa tgaatttgct ggttgaaaaa tcaacaaaaa caacatactg
    25141 acagacaaaa ccccggaatg accggcatta ccggggctta gggaagattt acttctgtaa
    25201 ccaccagaca gcctcaaaag gccgtaaatt catggcacag ggttgtggtg aggcttcttc
    25261 gtagttatgc atcacaagct gccagttgcc gcgcatttgc cctgcctgcc agggttggat
    25321 ctcacggcta aggttggcaa tgaccagcaa ggtttgcccc ttccattcac ggcgatagca
    25381 ccacaataca gggctgtttg gcagcagatc ctggtaattg ccccatgtca ggatggcttc
    25441 ctgcttacgc agtgcgatta acttttggta ggtgtaaaac accgaggaat catcggccag
    25501 cgcggcttct acgttgattt gttgatagtt atcgcccagg ccaatccacg gttcgccagc
    25561 cgtaaacccg gcattatcgc cgttgctcca ttgcatgggc gtgcgactgt tgtcacggga
    25621 tttactggcg aggattgcca ataactcgtc ggcatcacgc ccatcgttgc gcagctcggc
    25681 aaacatattg aggctctcta cgtcgcgata gtcagtaatg cgcgtgaaat gcgggttggt
    25741 catgccaatc tcttcgccct ggtagatata cggcgttccc tgcatgccat gcagcaccat
    25801 cgccagcatt tttgccgcag gcacgcggta ttcaccttca tcaccaaagc gagaaacaat
    25861 gcgcggctga tcgtggttac accagaacaa ggcattccat gctacgttgt gcattccttg
    25921 ttgccagtgg cggaacaatg ttttcaacgc cacaaagtca ggtttagcca gcgtccattt
    25981 ttcaccaccg ggataatcga ccttcaggtg atgaaaatta aaggtcatcg acaattcact
    26041 gcctgtcaga gccgcgtatc gctggcaatg ctcaaggctg gtggaggaca tttcacctac
    26101 ggtcattaac ccgcgtggcg taaacacatc gcggttcatc tcgtgcaaaa actcgtgtgc
    26161 tcgtggcccg tcggtgtaga agcgacgccc gtcgccgtcc aggtcttcag ggaaacgcgg
    26221 gtctttggag atcagattca ccacatccag gcgcaacccg tcgaccccac gatcggccca
    26281 gaactcacag acttttttca gctctgcgcg taccgctgga ttctcccagt tgagatccgc
    26341 ctgttctggt gcaaagagat gcaaatagta ctgttcgctt tccgcatgcc agcgccacgc
    26401 actaccgcca aattttgaac gccagttgtt cggtggcgtt tctggttctc catcgcgcca
    26461 gatataaaac tggcggtaag ggctttcttt gttcagcgcc tcgcgaaacc aggcatgttg
    26521 ggtagaggta tggttaaaca ccatatcgag aatgatacga atcccgcgcg attttgcctg
    26581 cgtcaccagt tcgtcaaaat cgtccagcgt gccgtaggtg ggatcaatcg ccgtatagtt
    26641 cgctacgtcg taaccgttat cgacctgggg agagacataa aagggggtta gccagatggc
    26701 atcaacgccc agtttatgca gatagtccag gtgttggata acgccacgta aatcgccggt
    26761 accgctaccc gtggtgtcct gaaaactctt tggataaatc tggtagataa cgccgttttg
    26821 ccaccagtgg ggaagatgag tcattacgtt attcctgcga atgcgagggg gcgcaattgc
    26881 gccccgaaga aaattaaaca atgtccagcg tgcccaggcg gtatttccgc tgatagataa
    26941 acgaggtgag tacaatcggg atgatgatgg cgatagccat tgccagcgca aacacctgcc
    27001 agtagctcgg ttgaatcgag agaattcccg gcaggccgcc tacgccgatg ccattcgcca
    27061 taacgccgtt caggccgcat agcaatcctg ccagaccaga accaatcatc gcgcacagca
    27121 tcgggaagcg atatttcagg ttgatgccgt acattgcagg ctcagtgacc ccaagccagg
    27181 cggagatcgc cgcaggcacg gagatctcgc gttcattgtg cttgcggctg gaaatgataa
    27241 tgcctatcac ggcggagccc tgagcgatat tcgacagcgc aatcagcggc cacactggcg
    27301 taccacccat gctttgaatc atctgcaaat caatagcaag cgtggtctgg tgtaccccgg
    27361 tgatcaccag cggggcgtac aggaagccaa acaatgccgc gccaatcgga gcaaagctgc
    27421 cggtcatcag gtgacgtacc gcaaaggcaa cgccatcgcc aatcatgcgt ccaaacggac
    27481 caatcagcgc atgggcgagg aacaccgcga ggatcagcga acagacgggc accaccacca
    27541 gatagaggta atccggcacg atgcgtttaa ggcgagtttc aataacgccc agcgccagcc
    27601 cggctaatag tgccgggatc acctgcgcct gatagcccac tttggcgatg ctgaacatgc
    27661 caaagtccca cacttccggc agctgctgcc cgagcagata agcgttcatc agctgggggg
    27721 aaaccagtgt cacgccaagc acgataccaa ggatcggcgt gccgcccatt tttttcaccg
    27781 ctgaccagca aatcccgacc ggcaggtaga agaagatcgc ttcaccgatc aaccacagaa
    27841 aatcgtagat cgtttgcagg gaagggtaca tttgtgccag cgtttgaccg ttgctcatgg
    27901 gcaaatcgcc gattacattg cgaaaaccga ggatcaaacc gccgctaatc aacgcgggca
    27961 gcaacgggaa gaagatctcc gcgaaatgag agatcaactg ctcatgccat ttcatattct
    28021 gccgggcggc tttttttacc tgctctttat caacctgcgc ctgtccggtt gacgctatca
    28081 gtgcttgata gtaatcaccc acgttggtgc caatcaccac ctgaaattgc ccggcattgg
    28141 tgaaacagcc tttcaccatg gggagttgct caatttcttt cggtctggca ttggccggtt
    28201 ggttgaggac aaagcgcagg cgagtaatac agtggctcac cgtcgcaata ttgccgcgcc
    28261 cgccgaccag ttcaatcaac cgatcgatat ccgtttggtt tattttgctc atcataaagc
    28321 cccatggcag atgacatttt tggttggctg cagaatatat tgcgcggaaa aatttaaaaa
    28381 cgggaacgtt cccgaaacgc agcgaagatc acaatttatc gttcaggaaa cgatcaggac
    28441 agggtggcgg ggatgatgat ttgttgcggt tcgctgcgcc cggttacctg tgcgatcaac
    28501 tggcaggccg cctggcgtcc agcttcggcg taaccgggat ctacggtgac gatctccgga
    28561 tggaggaatt tcattaacgg cgtattaccg acgctcgcca gttgcaaggt gtcgatgcgt
    28621 tgctcttgca ggtatttact tgcgccaagt gccagcgtgt cggttgcgca cagtaaggcg
    28681 gtagtttcag gcgtaatcac ttttgctacg ttctcatagc cttgcttcat agcaaggcct
    28741 ggcagggcgg caacgggatg cagtttatgc gctttgcaga acgccaggta ggcttcgtga
    28801 cgtcgcttac cggttgtcac gtcactgtgc ggcacgccga gataactgat attacgatgc
    28861 ccctggtcat acagccgttg catcaggatc ttgattgccc cttcgtcgtc ataacagacc
    28921 gaagcaaagc cttttgcgtc acgcgccagc agaaccagcg atgactgcca gtgggctaac
    28981 atttcttctg ttatgccagt aaaaccgaac agcactacgc cgtcgatatt acgccgtttc
    29041 agcaccccca aatgttcggc aactaattgc ggggaaaact gactttccat catgattggg
    29101 tcgtaacctt gttcatagaa cgctggcagc atggtttgaa cggcgagatt ttctgacaac
    29161 gaatccagac gggtaacaat gatggcgacc actttatcgc tttgcccacg catagcgcgc
    29221 gcagagcggg aaggggaaaa tccatgctga ttcatcactg cttcaacacg ctcgcgggtg
    29281 agctggctca cgccgctttc gttattcagc acccgggaaa ctgtagattt ccccacgccg
    29341 cttaagcgcg cgatatcttt gatggtcagc cgattttgca tcctgttgtc ctgtaacgtg
    29401 ttgtttaatt atttgagcct aactttaccc gtgcattcag caatgggtaa agtctggttt
    29461 atcgttggtt tagttgccag caggtattat atcgccatag atgctacgaa tattattgga
    29521 ttctccttat tatttgcggc gcttttttca cttaccggag gttatatgga acctgatccc
    29581 acgcctctcc ctcgacggag attaaaactt ttccggtaag cccgtctttt cacggcgtta
    29641 ccggatgcgt aaggccgtga cgttttaacg tccctgctca gctttattac cttcaggtaa
    29701 ggcttcgcca cgcctgaaga catttctgta ctgtttcaga cagtgcggag ggactcctta
    29761 tgtttaaaga aatttttacc cggctcactc gccatttacc ttcccgtctg gttcatcgtg
    29821 atccattgcc tggcgcgcag cagacagtga atacggtggt cccgccgtcc ttaagtgcgc
    29881 attgcctgaa aatggcggtg atgcccgaag aagaattgtg gaaaacgttc gacacccatc
    29941 cggaagggtt aaatcaggcg gaagtggaat ctgcccgcga acaacatggt gaaaataaat
    30001 tacccgcaca acaaccgtcg ccgtggtggg tacatttatg ggtctgctat cgcaacccct
    30061 ttaatatttt actcaccatt ctcggcgcta tttcttacgc cacggaagat ttatttgctg
    30121 cgggcgttat cgcgctaatg gtcgctattt ctacgttgct gaactttatt caggaagcac
    30181 gttccactaa agcggcagat gccctgaaag cgatggtcag caatactgcg acggtgctgc
    30241 gcgtaattaa cgacaaaggc gaaaatggct ggctggagat cccgatcgac cagctggtgc
    30301 ccggcgatat tataaaactg gcggcgggag atatgatccc ggcagattta cgtatcttgc
    30361 aggcgcggga tctgttcgtc gctcaggcgt cgttaaccgg tgagtctctg cccgtagaaa
    30421 aagccgctac cactcgccag ccggagcaca gcaatccgct ggagtgcgac acgctgtgtt
    30481 ttatgggcac caccgtggtg agcggcacgg cacaagcaat ggtgattgct acaggtgcca
    30541 atacctggtt tggtcaactg gcggggcgtg ttagtgagca ggaaagcgag ccgaatgcct
    30601 ttcagcaagg gatcagccgc gtcagtatgc tgctgattcg ctttatgctg gtgatggcac
    30661 cggtggtgct gttaatcaat ggctacacca aaggcgactg gtgggaagcg gcgctgtttg
    30721 cgctttcggt cgcggtaggc ctaacgccgg aaatgttgcc gatgattgtt acctcgacgc
    30781 tggcgcgcgg cgcagtaaag ctgtcgaaac agaaagtgat cgtcaaacat ctggatgcta
    30841 ttcagaactt tggcgcaatg gatattctgt gcactgataa aaccggcacc ctgacacagg
    30901 ataaaattgt gctggagaat cataccgata tctccggtaa aaccagcgaa cgcgtgctgc
    30961 atagcgcgtg gttgaacagt cattatcaga ccggacttaa aaacctgctc gatacagcgg
    31021 tgctcgaagg tacggatgaa gagtcagcgc gctcgctggt cagtcgttgg caaaaaatcg
    31081 atgagattcc gtttgatttc gagcgtcgcc ggatgtcggt ggtagtggca gaaaataccg
    31141 agcaccatca gctggtttgc aaaggcgcat tgcaggaaat cctcaatgtg tgttcgcaag
    31201 tgcgtcacaa tggcgagatt gtaccgctcg atgacatcat gctgcgtaag attaagcggg
    31261 ttactgatac gctgaatcgt caggggctgc gcgtggttgc ggtggcgacg aaatacctgc
    31321 cagcgcgtga aggagattac cagcgggcgg atgaatccga cctgatcctc gaaggatata
    31381 ttgctttcct tgatccgcca aaagagacaa ccgctccggc actgaaggca ttaaaagcga
    31441 gtggaattac cgtaaaaatc cttactggcg acagtgagtt agttgcagcg aaagtgtgcc
    31501 atgaagtggg gctggacgcg ggagaggtgg tcattggtag tgatattgaa atgctatctg
    31561 acgacgaact ggcaaatctt gcacagcgca ccacgctgtt tgcccgcctg acgccgatgc
    31621 ataaagaacg cattgtgacc ttactgaagc gcgaagggca tgtggttggc tttatgggcg
    31681 atggtattaa tgatgcgccc gccttacgcg ctgcggatat cggcatttct gtggacggcg
    31741 cggtagatat tgcccgtgaa gcggctgata tcatcctgct ggaaaaaagc ctgatggtgc
    31801 tggaagaggg ggttattgag ggacgtcgca ctttcgccaa catgctgaaa tacatcaaaa
    31861 tgacggcgag ctctaacttc ggtaatgtgt tcagcgtgct ggtagcgagt gctttcttgc
    31921 ccttcctacc gatgttgccg ttacacttgc ttattcagaa cctgctgtac gatgtgtcac
    31981 aggtggcgat cccgtttgat aacgtcgacg acgagcaaat tcaaaagccg cagcgttgga
    32041 atccggcgga tctggggcgc tttatgatct tcttcggacc gatcagctcg atcttcgata
    32101 ttttgacgtt ttgcctgatg tggtgggtat tccatgccaa cacgccggaa acgcaaacgc
    32161 tgttccagtc gggatggttt gtggtgggct tactgtcgca aacgctgatt gtgcatatga
    32221 tccgcacccg ccgtgtgccg tttattcaga gctgtgcatc gtggccgtta atgatcatga
    32281 ccgtgatcgt gatgattgtc gggatcgcat tgccgttttc accgctggcc agttatctgc
    32341 aattacaggc gttgccgtta agctatttcc cgtggctggt tgcgattctg gcagggtata
    32401 tgacgttaac ccagttggtg aaagggttct atagccgtcg ttacggctgg cagtaaagaa
    32461 taaactgggc atggtggccc ggattcagat tgcagacaaa gtgagttttg ttcatgccgg
    32521 atgcggcgta aacgcctaat ccggtctaca aattcaataa attgcaggaa tcacgtaggc
    32581 ctgataagcg tagcgcatca ggcgattttg cgtttgtcat cagacttaat ccgggcatga
    32641 tagcccggat ttccatcaag attagcgacg aacagcgatc gcttcgatct caatcttcac
    32701 gtctttcggc agacgggcaa cttcaacgca agaacgtgcc gggaaggcgg cgttgtgttc
    32761 ggtgaagaag gcttcgtaag tggcgtttac ggttgcgaag tcgttcagat cttttacaaa
    32821 cacggtagtt ttaacgatgt cgcccacttt cagaccagcg gcttcgacga tcgcttttac
    32881 gttatccagc gactgacgtg cctgtgcagc gacgtctgcc ggtacttcgc ccgttttcgg
    32941 atttaccggg atctgaccgg aggtgatgat catattgccc agatcaacgc cctgtacgta
    33001 agggccgata gctgccggtg cattttccgt cgcgatagtt ttgctcatga tttctccttt
    33061 attacagcgg taaaaagtct ggctcattat agggagccag acttttatta ccaaccgcaa
    33121 ttaattggcc agcaccacat tatgggaaaa ctctttttca cagtatttgc atttgagcgc
    33181 gatgtcattg gcgcgttttc gcacggcaaa gctggatgaa accggttcgg catggctgat
    33241 acagttgctg ttcgggcaga ccagcacatt gtcgatgcgc tccggcagac ttgggcgcga
    33301 tttacccacc acttcatagt tgtcgatacg gttaaccgtg gcttgcggcg catacaatgc
    33361 cagttgatct acctggtctt cactcaaaaa ggtattttcg attttgatca gatctttgcg
    33421 gcccatctcg ccagaaggca ggttcagacc gatggtgatg cgctgatccg tttcggtcag
    33481 cttgaacaga ctcaacagct taaaaccgat ctgggcgggg atatggtcaa ttaccgtgcc
    33541 gcgtttaata gcttcaacct gcaatttatt atcgtgtgtc atctctattt ccccttacag
    33601 taccagatcg cgattcagaa ccagtgccag taacgcctgg cgagcgaaaa tcccgttgcc
    33661 tgcctgctgg aagtaccagg cgtgtggcgt tttatcaaca tccgtcgcaa tctcatcaac
    33721 acgcggcagc ggatgcagca ctttcatatt ggctttggcg ttgtggagat cgctggcgcg
    33781 aagaacaaac tgcgctttca cgttggcgta ctcggacggg tccagacgct ctttttgcac
    33841 gcgggtcatg tacaggatgt caacttccgc catcacttct tcaatagagc tgtgcagact
    33901 ccaggcgatc cctttttcat caagcatatc cagaatgtat tgcggcattg ccagcgcgtc
    33961 cggcgcgatg aagtaaaaac ggttgccgtc gaacttcgct aacgcctgag tcagggagtg
    34021 aacggtgcgg ccatatttca ggtcaccaac cattgcgacg tggagattgt ccagacgccc
    34081 ctgggtttcc tgaatagtga ataagtccag caaggtttgc gtcggatgtt ggttggagcc
    34141 atcaccggca ttcagtaccg gtacattgcc ggaaaactcg gtggccaggc gcgccgcacc
    34201 ttcctgcgga tgacgcatca ctatcgcatc aacgtaagtg ctgataaccg aaatggtatc
    34261 ggccagcgtt tcgccctttt tacccagtga tgtattggcg ctgtcggaaa agcccaccac
    34321 gctggcaccc aggcggtgca tggaagtttc gaaagagagg cgggtacggg tagaggcttc
    34381 gaagaaacag ctggcaatga ctttgtgctt caacagctct ggttgcgggt ttgctttcag
    34441 tttcgccgct gtcgccagca ccagattaag gtcatcgcga ctaaggtcgt ttatggaaat
    34501 gatatgtttc tgatatagcg gattagccat cttttatctc ctgacgcctg ggcaaaaaaa
    34561 agcccctcga ttgaggggct gggaatgggt gatcaacggg aagaaaaacg gcaggccagc
    34621 gtcttttttc agacgcggta agacaaaatg tcgaacacac tgaaccatac atcctcccgg
    34681 caaattgtcc ggcattatac tcatcgtcag aagcggtgca agcatttgat gcaatatttt
    34741 gtcagcgcaa acggtttata tgaatttaaa gtcaaaatat atgcattttt atttactgtg
    34801 attctggagg ggaactgtcg ttcggtatca ataattgcag acatttcctg cttttttctt
    34861 tttcactttc acgcaatcag atatgcattt tattccattc atccgactta taggacggag
    34921 tgtgaaaacg aacggctaac actattgctt actgctcagg gatgcgcgct atcactttaa
    34981 tttcaaaatc aaagcctgcc agccatgtaa cacccaccgc cgtccagttt ggataaggtg
    35041 gggcgctaaa tatttcattt ttcaccgtca tgatgtcttc gaattgtttt tctggatcgg
    35101 tatgaaagct cgtaacatca atgatatcgt caaaagtgca tcccgcagct gccagggtcg
    35161 catgcaaatt atcaaatgcc agtctgactt gttgctgaaa atcgggttct ggtgttccgt
    35221 cctctcgact tcctacttgc ccggaaacaa acagcaaatc gccggaacga atagccgcag
    35281 aataacgatg ctcagcatac agtgaatgtc gtccagcagg gaaaacagcg gttctttcta
    35341 ccatttggtt atcctcaaga tttacgacat gaacagaaga tttatattta ccaggagccg
    35401 cttttagcgg acgacgtgag taaacaaaac ccagacatca tgggaaatgg ctgggcttaa
    35461 ttgagcgtag tcggttatgc gccaaacgcg ccatcaatgg tatgcatcgc gccggtaaca
    35521 aaactggctt ctggccctgc taaccatgcg accataccag cgacctcttc cggttgccca
    35581 tgtcttttga tggccataaa accatgcaac atatcgcgca ttggcccgtt ggcgggatta
    35641 gcgtcggtat caattggccc tggctggacg acgttgatgg tgatcccacg cggtccaaaa
    35701 tcacgggcca gcccgcgcgc catgccttgt agggcagatt tacttgcggc ataagcagcc
    35761 atgcctgcaa caggcatacg atcgccattc acggagccga tgattaagat gcgcccgcct
    35821 tcgggcatct gccgggcggc ttcaacagag gcatggtaag gagcatgaat attgattttg
    35881 aaaaggcgat caatatcgtc ggcatttaat tccagggcat cgccaaagac gccaatacct
    35941 gcatttacca ccaggatatc caatgcgccg ctcttacgaa cgacatcaat gacagcgtct
    36001 ctgtcagcac tatctgtgaa tactgctgtc gctccagtct cttgtgccag gtgttcagcg
    36061 gcatctttcg accccgcata ggtgaatcgt acattggccc catcggtgac gaaacgacgt
    36121 acgatagcgg caccgatacc acgactgcca ccgaggatga gaactgtctt acctgtaaaa
    36181 gcgcccataa ggactccttg atttattatg taacatgcat tacaaaactg ttttaacttt
    36241 ctgtcaataa gttttgtaat ggtcactaaa aaacaatctc gcgttccagg tcgtcccaga
    36301 cgtttcgctc ctgagcaggc agtctctgcg gcaaaagtgc tttttcacca aaaaggtttc
    36361 gatgctgtca gtgttgctga agttactgat tatcttggta ttaacccccc gagcctctac
    36421 gcggcttttg gcaataaggc tgggttattt agccgtgtac tcaatgaata tgtcggtacg
    36481 gaagctattc cgcttgccga tattcttcgt gatgatcgtc cggtagggga gtgcctggct
    36541 gaggtattaa aagaagcggc gcgcagatat agccaaaacg gcggctgcgc tggctgtatg
    36601 gttcttgaag gcattcatag tcatgatcca caagcgcgtg atattgccgt tcaatattat
    36661 cacgccgcag aaacggccat ttatgactat atcgccaggc ggcatccaca aagcgcacaa
    36721 tgtgtgactg attttatgag taccgtgatg tcagggcttt ctgcgaaggc acgggagggg
    36781 cactccatcg aacaactctg tgcaacagct gcactggcgg gggaagcgat aaaaactatt
    36841 ctcaaggagt gatgcgggcc ttgacccgaa aggcgggaac gcgcctgccg ataagttgtg
    36901 ataagacaat aattcacgcg ttaaggctag cggaattgat catcttttcg tataacgata
    36961 gaaatgaaac gttgttttaa ttaaggagtg gaaaagatga tcatcggaaa tattcataat
    37021 cttcagccgt ggctacccca ggagttacgc caggcgattg agcatatcaa agcacacgtt
    37081 acggcagaaa cgccaaaggg caagcacgat atcgaaggca atcgtctgtt ttatcttatc
    37141 tcggaagata tgaccgagcc gtacgaagct cgccgtgcgg agtaccatgc ccgctatctc
    37201 gacattcaga ttgtgttaaa aggtcaggaa ggcatgacct tcagcacaca acctgcaggt
    37261 acgccggata ccgactggtt agctgataaa gacatcgcat ttttgccgga aggtgttgat
    37321 gagaaaacag ttatccttaa tgaaggtgat tttgttgtgt tttatccggg ggaagtgcat
    37381 aaaccgctgt gcgcagtggg cgcgccagcc cgggttcgca aagcagtagt gaagatgctg
    37441 atggcgtgat gacttttcgc cgtaaataac tccaggttta cggcgagttt gtgaaaagag
    37501 cgttttttga tatttttttg tgagtaaaat ttgtaatgct tagacgttct tattaactca
    37561 aggagttcgt catgagcaaa atatcagatt tgaattattc tcaacacatt acattagccg
    37621 acaattttaa acaaaaaagt gaagttttaa atacctggcg tgttggaatg aataattttg
    37681 cccgtaatgc cgaggggcag gataacacaa gaaatatcct tgatcctaag acatttttgg
    37741 aatttttggt aaaaatattt actttaggtt atgtggattt tagcaaacgc tccaacgaag
    37801 cgggaagaaa tatgatggct catattgagt cctcatctta tatcaaaaat aatgatggca
    37861 gtgagataat gaagtttgtt atgaataatc ctgaagggga acgagcggat ttatctaagg
    37921 tggaaataga aatcacactt tccgctttca ctactatggg gactcgtcaa ggacatacgg
    37981 ctattatatt tcaacaacct gatggttcga ctaatcgtta tgaaggaaag tcctttgaaa
    38041 gaaaagatga gagttcatta cacctgatta ctaacaagat tctggcatgt taccaacgcg
    38101 aagctaacaa ggaaatagct cgtctattaa atattccgca ggagttaaat aattctcagg
    38161 acttgaataa ctcgcaggtg agttgtaaag attcagttga ttctacgatt acggatttat
    38221 tagaaaaacc attgaacaat gcattattag caataaggaa agaacatctg ctattaatgc
    38281 cttatgtatg taatgaatcg atttcatact tgcttggtga aaaagggata ctgaa
//
LOCUS       DAPGUL010000035        38021 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.035, whole genome shotgun sequence.
ACCESSION   DAPGUL010000035 DAPGUL010000000
VERSION     DAPGUL010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 38021)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38021)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38021
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.035"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(96..383)
                     /locus_tag="RHX21_001943"
     CDS             complement(96..383)
                     /locus_tag="RHX21_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebO family protein"
                     /protein_id="HDV1987125.1"
                     /translation="MNEVVNSGVMNIASLVVSVVVLLIGLILWFFINRASSRTNEQIE
                     LLEALLDQQKRQNALLRRLCEANEPEKADKKTIESQKSVEDDDIIRLVAER"
     gene            complement(458..601)
                     /gene="mgrB"
                     /locus_tag="RHX21_001944"
     CDS             complement(458..601)
                     /gene="mgrB"
                     /locus_tag="RHX21_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoP/PhoQ regulator MgrB"
                     /protein_id="HDV1987126.1"
                     /translation="MKKFRWVVLVVVVLACLLLWAQVFNMMCDQDVQFFSGICAINQF
                     IPW"
     gene            760..999
                     /locus_tag="RHX21_001945"
     CDS             760..999
                     /locus_tag="RHX21_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987127.1"
                     /translation="MRFIIRTVMLIALVWIGLLLSGYGVLIGSKENAAGLGLQCTYLT
                     ARGTSTVQYLHTKSGFLGITDCPLLRKSNIVVDNG"
     gene            complement(1142..1933)
                     /gene="kdgR"
                     /locus_tag="RHX21_001946"
     CDS             complement(1142..1933)
                     /gene="kdgR"
                     /locus_tag="RHX21_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator KdgR"
                     /protein_id="HDV1987128.1"
                     /translation="MANADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMS
                     KSTVYRFLQTMKTLGYVAQEGESEKYSLTLKLFELGARALQNVDLIRSADIQMREISR
                     LTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDLDEV
                     KQILEGVEYKRSTERTITSTEALLPVLDQVREQGYGEDNEEQEEGLRCIAVPVFDRFG
                     VVIAGLSISFPTLRFSEERLQEYVAMLHTAARKISAQMGYHDYPF"
     gene            2110..3483
                     /locus_tag="RHX21_001947"
     CDS             2110..3483
                     /locus_tag="RHX21_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416342.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1987129.1"
                     /translation="MPKVQADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIAT
                     DLHATPASSIWVVNAYQIAIVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSD
                     SLQMLTLARVIQGFGGAALMSVNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIA
                     AAILSIASWKWLFLINVPLGIIALLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLL
                     ITALSGFAQGQSLTLIAAELVVMVVVGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICT
                     SVCSFCAQMLAMVSLPFYLQTVLGRSEVETGLLLTPWPLATMVMAPLAGYLIERVHAG
                     LLGALGLFIMAAGLFSLVLLPASPADINIIWPMILCGAGFGLFQSPNNHTIITSAPRE
                     RSGGASGMLGTARLLGQSSGAALVALMLNQFGDNGTHVSLMAAAILTVIAACVSGLRI
                     TQPRSRA"
     gene            complement(3529..4410)
                     /gene="htpX"
                     /locus_tag="RHX21_001948"
     CDS             complement(3529..4410)
                     /gene="htpX"
                     /locus_tag="RHX21_001948"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014229823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease HtpX"
                     /protein_id="HDV1987130.1"
                     /translation="MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSVQGLMIMALLFGF
                     GGSFVSLLMSKWMALRSVGGEVIEQPRNERERWLVNTVATQARQAGIAMPQVAIYHAP
                     DINAFATGARRDASLVAVSTGLLQNMSPDEAEAVIAHEISHIANGDMVTMTLIQGVVN
                     TFVIFISRILAQLAAGFMGGNRDEGEESNGNPLIYFAVATVLELVFGILASIITMWFS
                     RHREFHADAGSAKLVGREKMIAALQRLKTSYEPQEATSMMAFCINGKSKSLSELFMTH
                     PPLDKRIEALRTGEYLK"
     gene            complement(4602..6650)
                     /gene="prc"
                     /locus_tag="RHX21_001949"
     CDS             complement(4602..6650)
                     /gene="prc"
                     /locus_tag="RHX21_001949"
                     /EC_number="3.4.21.102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxy terminal-processing peptidase"
                     /protein_id="HDV1987131.1"
                     /translation="MNMFFRLTALAGLLAIAGQTFAVEDITRADQIPVLKEETQHATV
                     SERVTSRFTRSHYRQFDLDQAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTELGD
                     ELRSGKLDVFYDLYNLAQKRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEA
                     ELNALWDSKVKFDELSLKLAGKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAF
                     AREIDPHTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAI
                     SVGDKIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGKGTKTRTVTLT
                     RERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDL
                     RSNGGGALTEAVSLSGLFIPAGPIVQVRDNNGKVREDSDTDGQVFYKGPLVVLVDRFS
                     ASASEIFAAAMQDYGRALVVGEPTFGKGTVQQYRSLNRIYDQMLRPEWPALGSVQYTI
                     QKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAATYVKSGDLTA
                     FGPELLKEHNARIAKDPEFQNIMKDIARFNAMKDKRNIVSLNYAVREKENNEDDATRL
                     ARLNERFKREGKPELKKLDDLPKDYQEPDPYLDETVNIALDLAKLEKARPAEQPAPVK
                     "
     gene            complement(6670..7368)
                     /gene="proQ"
                     /locus_tag="RHX21_001950"
     CDS             complement(6670..7368)
                     /gene="proQ"
                     /locus_tag="RHX21_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707288.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone ProQ"
                     /protein_id="HDV1987132.1"
                     /translation="MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVD
                     RVAGEMNLSKTQLRSALRLYTSSWRYLYGVKPGATRVDLDGNPCGELDEQHVEHARKQ
                     LEEAKARVQAQRAEQQAKKREAAAAAGEKEDAPRRERKPRPTTPRRKEGAERKPRAQK
                     PVEKAPKTVKAPREEQHTPVSDISALTVGQALKVKAGQNAMDATVLEITKDGVRVQLN
                     SGMSLIVRAEHLVF"
     gene            complement(7465..7962)
                     /gene="msrC"
                     /locus_tag="RHX21_001951"
     CDS             complement(7465..7962)
                     /gene="msrC"
                     /locus_tag="RHX21_001951"
                     /EC_number="1.8.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine (R)-S-oxide reductase"
                     /protein_id="HDV1987133.1"
                     /translation="MNKTEFYADLNRDFNALMAGETSFLATLANTSALLYERLTDVNW
                     AGFYLLEDDTLVLGPFQGKIACVRIPVGRGVCGTAVARNQVQRIEDVHAFDGHIACDA
                     ASNSEIVLPLVVKNQIIGVLDIDSTVFGRFTDEDEQGLRQLVAQLEKVLATTDYKKFF
                     ASVAG"
     gene            8092..9375
                     /gene="yebS"
                     /locus_tag="RHX21_001952"
     CDS             8092..9375
                     /gene="yebS"
                     /locus_tag="RHX21_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity lipid transport subunit YebS"
                     /protein_id="HDV1987134.1"
                     /translation="MALNTPQITPTKKITVRAIGEELPRGDYQRCPQCDMLFSLPEIN
                     SHQSAYCPRCQAKIRDGRDWSLTRLAAMAFTMLLLMPFAWGEPLLHIWLLGIRIDANV
                     MQGIWQMTKQGDTITGAMVFFCVIGAPLILVSSIAYLWFGNRLGMNLRPVLLMLERLK
                     EWVMLDIYLVGIGVASIKVQDYAHIQAGVGLFSFVALVILTTVTLSHLNVEELWERFY
                     PQRPATRRDEKLRVCLGCHFTGYPDQRGRCPRCHIPLRLRRRHSLQKCWAALLASIVL
                     LLPANLLPISIIYLNGGRQEDTILSGIMSLASSNIAVAGIVFIASILVPFTKVIVMFT
                     LLLSIHFKCQQGLRTRILLLRMVTWIGRWSMLDLFVISLTMSLINRDQILAFTMGPAA
                     FYFGAAVILTILAVEWLDSRLLWDAHESGNARFDD"
     gene            9344..11977
                     /gene="yebT"
                     /locus_tag="RHX21_001953"
     CDS             9344..11977
                     /gene="yebT"
                     /locus_tag="RHX21_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416348.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-binding membrane homeostasis protein YebT"
                     /protein_id="HDV1987135.1"
                     /translation="MSQETPASTTEAQIKNKRRISPFWLLPFIALMIAGWLIWDSYQD
                     RGNTVTIDFMSADGIVPGRTPVRYQGVEVGTVQDISLSDDLRKIEVKVSIKSDMKDAL
                     REETQFWLVTPKASLAGVSGLDALVGGNYIGMMPGKGKEQDHFVALDTQPKYRLDNGD
                     LMIHLQAPDLGSLNSGSLVYFRKIPVGKVYDYAINPNKQGVVIDVLIERRFTDLVKKG
                     SRFWNVSGVDANVSISGAKVKLESLAALVNGAIAFDSPEESKPAEAEDTFGLYEDLAH
                     SQRGVIIKLELPSGAGLTADSTPLMYQGLEVGQLTKLDLNPGGKVTGEMTVDPSVVTL
                     LRENTRIELRNPKLSLSDANLSALLTGKTFELVPGDGEPRKEFVVVPGEKALLHEPDV
                     LTLTLTAPESYGIDAGQPLILHGVQVGQVIDRKLTSKGVTFTVAIEPQHRELVKGDSK
                     FVVNSRVDVKVGLDGVEFLGASASEWINGGIRILPGDKGEMKASYPLYANLEKALENS
                     LSDLPTTTVSLSAETLPDVQAGSVVLYRKFEVGEVITVRPRANAFDIDLHIKPEYRNL
                     LTSNSVFWAEGGAKVQLNGSGLTVQASPLSRALKGAISFDNLSGASASQRKGDKRILY
                     ASETAARAVGGQITLHAFDAGKLAVGMPIRYLGIDIGQIQTLDLITARNEVQAKAVLY
                     PEYVQTFARGGTRFSVVTPQISAAGVEHLDTILQPYINVEPGRGNPRRDFELQEATIT
                     DSRYLDGLSIIVEAPEAGSLGIGTPVLFRGLEVGTVTGMTLGTLSDRVMIAMRISKRY
                     QHLVRNNSVFWLASGYSLDFGLTGGVVKTGTFNQFIRGGIAFATPPGTPLAPKAQEGK
                     HFLLQESEPKEWREWGTALPK"
     gene            12057..13496
                     /gene="rsmF"
                     /locus_tag="RHX21_001954"
     CDS             12057..13496
                     /gene="rsmF"
                     /locus_tag="RHX21_001954"
                     /EC_number="2.1.1.178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416349.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1407)-C(5))-methyltransferase
                     RsmF"
                     /protein_id="HDV1987136.1"
                     /translation="MAQHTVYFPDAFLTQMREAMPSTLSFDDFLAACQRPLRRSIRVN
                     TLKISVADFLQLTAPYGWTLTPIPWCEEGFWIERDNEDALPLGSTAEHLSGLFYIQEA
                     SSMLPVAALFADDNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHA
                     NISRCGISNVALTHFDGRVFGAAVPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESN
                     QEIAATQRELIDSAFHALRPGGTLVYSTCTLNQEENEAVCLWLKETYPDAVEFLPLGD
                     LFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPALPAPKYKVGNFPFSPVKD
                     REAGQIRQAAAGVGLNWDENLRLWQRDKELWLFPVGIEALIGKVRFSRLGIKLAETHN
                     KGYRWQHEAVIALASPDNMNAFELTPQEAEEWYRGRDVYPQAAPVADDVLVTFQHQPI
                     GLAKRIGSRLKNSYPRELVRDGKLFTGNA"
     gene            13614..13850
                     /locus_tag="RHX21_001955"
     CDS             13614..13850
                     /locus_tag="RHX21_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707284.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1480 family protein"
                     /protein_id="HDV1987137.1"
                     /translation="MKTSVRIGAFEIDDGELHGESPGDRTLTIPCKSDPDLCMQLDAW
                     DAETSIPALLNGEHSVLYRTRYDQQSDAWIMRLA"
     gene            13955..14146
                     /locus_tag="RHX21_001956"
     CDS             13955..14146
                     /locus_tag="RHX21_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebW family protein"
                     /protein_id="HDV1987138.1"
                     /translation="MFALVLFVCYLDGGCEDIVVDVYNTEQQCLYSMSDQRIRHGGCF
                     PIEDFIDGFWRPAQEYGDF"
     gene            complement(14147..14803)
                     /gene="pphA"
                     /locus_tag="RHX21_001957"
     CDS             complement(14147..14803)
                     /gene="pphA"
                     /locus_tag="RHX21_001957"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416352.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase"
                     /protein_id="HDV1987139.1"
                     /translation="MKQPAPVYQRIAGHQWRHIWLSGDIHGCLEQLRRKLWHCRFDPW
                     RDLLISVGDVIDRGPQSLRCLQLLEQHWVCAVRGNHEQMAMDALASQQMSLWLMNGGD
                     WFIALADNQQKQAKTALEKCQHLPFILEVHSRTGKHVIAHADYPDDVYEWQKDVDLHQ
                     VLWSRSRLGERQKGQGITGADHFWFGHTPLRHRVDIGNLHYIDTGAVFGGELTLVQLQ
                     "
     gene            complement(15199..15540)
                     /locus_tag="RHX21_001958"
     CDS             complement(15199..15540)
                     /locus_tag="RHX21_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebY family protein"
                     /protein_id="HDV1987140.1"
                     /translation="MMKKSILAFLLLTSSAAALAAPQVITVSRFEVGKDKWAFNREEV
                     MLTCRPGNALYVINPSTLVQYPLNDIAQKEVASGKTKAQPISVIQIDDPNNPGEKMSL
                     APFIERAEKLC"
     gene            complement(15553..16425)
                     /gene="copD"
                     /locus_tag="RHX21_001959"
     CDS             complement(15553..16425)
                     /gene="copD"
                     /locus_tag="RHX21_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis membrane protein CopD"
                     /protein_id="HDV1987141.1"
                     /translation="MLAFTWIALRFIHFTSLMLVFGFAMYGAWLAPLTIRRLLAKRFL
                     RLQQHAAVWSLISATAMLAVQGGLMGTGWADVFSPNIWQAVLQTQFGGVWLWQIVLAL
                     VTLIVALMQPRNMPRLLFMLTTAQFILLAGIGHATLNEGVTAKIHQTNHAIHLICAAA
                     WFGGLLPVLWCMQLIKGRWRHQAIQALMRFSWCGHFAVIGVLASGVLNALLITGFPPT
                     LTTYWGQLLLLKAILVMIMVVIALANRYVLVPRMRQDEDRAAPWFVWMTKLEWAIGAV
                     VLVIISLLATLEPF"
     gene            complement(16429..16803)
                     /gene="yobA"
                     /locus_tag="RHX21_001960"
     CDS             complement(16429..16803)
                     /gene="yobA"
                     /locus_tag="RHX21_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopC domain-containing protein YobA"
                     /protein_id="HDV1987142.1"
                     /translation="MTSTARSLRYALAILTTSLVTPSVWAHAHLTHQYPAANAQVTAA
                     PQAITLNFSEGVETGFSGAKITGPKNENIKTLPAKRNEQDQKQLIVPLADSLKPGTYI
                     VDWHVVSVDGHKTKGHYTFSVK"
     gene            16942..17172
                     /gene="holE"
                     /locus_tag="RHX21_001961"
     CDS             16942..17172
                     /gene="holE"
                     /locus_tag="RHX21_001961"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit theta"
                     /protein_id="HDV1987143.1"
                     /translation="MLKNLAKLDQTEMDKVNVDLAAAGVAFKERYNMPVIAEAVEREQ
                     PEHLRSWFRERLIAHRLASVNLSRLPYEPKLK"
     gene            17274..17930
                     /locus_tag="RHX21_001962"
     CDS             17274..17930
                     /locus_tag="RHX21_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HDV1987144.1"
                     /translation="MSFWKVAAAQYEPRKTSLTEQVAHHLEFVRAAARQQCQLLVFPS
                     LSLLGCDYSRRALPAPPDLSLLDPLCYAATTWRMTIIAGLPVEYNDRFIRGIAVFAPW
                     RKTPGIYHQSHGACLGRRSRTITVVDEQPEGMDMDPTCSLFTTGQCLGEPDLLASARR
                     LQFFSHQYSIAVLMANARGNSALWDEYGRLIVRADRGSLLLVGQRSSQGWQGDIIPLR
                     "
     gene            17954..18616
                     /gene="exoX"
                     /locus_tag="RHX21_001963"
     CDS             17954..18616
                     /gene="exoX"
                     /locus_tag="RHX21_001963"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease X"
                     /protein_id="HDV1987145.1"
                     /translation="MLRIIDTETCGLQGGIVEIASVDVIDGKIVNPMSHLVRPDRPIS
                     PQAMAIHRITEAMVADKPWIEDVIPHYYGSEWYVAHNASFDRRVLPEMPGEWICTMKL
                     ARRLWPGIKYSNMALYKTRKLNVQTPPGLHHHRALYDCYITAALLIDIMNTSGWTAEQ
                     MADITGRPSLMTTFTFGKYRGKAVSDVAERDPGYLRWLFNNLDSMSPELRLTLKHYLE
                     NT"
     gene            complement(18613..20673)
                     /gene="ptrB"
                     /locus_tag="RHX21_001964"
     CDS             complement(18613..20673)
                     /gene="ptrB"
                     /locus_tag="RHX21_001964"
                     /EC_number="3.4.21.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptidase B"
                     /protein_id="HDV1987146.1"
                     /translation="MLPKAARIPHAMTLHGDTRIDNYYWLRDDTRSQPEVLDYLQQEN
                     SYGHRVMASQQALQDRILKEIIDRIPQREVSAPYIKNGYRYRHIYEPGCEYAIYQRQS
                     AFSEEWDEWETLLDANKRAAHSEFYSMGGMAITPDNTIMALAEDFLSRRQYGIRFRNL
                     ETGNWYPELLDNVEPSFVWANDSWTFYYVRKHPVTLLPYQVWRHAIGTPASQDKLIYE
                     EKDDTYYVSLHKTTSKHYVVIHLASATTSEVRLLDAEMADAEPFVFLPRRKDHEYSLD
                     HYQHRFYLRSNRHGKNFGLYRTRLRDEQQWEELIPPRDNIMLEGFTLFTDWLVVEERQ
                     RGLTSLRQINRKTREVIGIAFDDPAYVTWIAYNPEPETARLRYGYSSMTTPDTLFELD
                     MDTGERRVLKQTEVPGFDAANYRSEHLWIVARDGVEVPVSLVYHRKHFRKGHNPLLVY
                     GYGSYGASIDADFSFSRLSLLDRGFVYAIVHVRGGGELGQQWYEDGKFLKKKNTFNDY
                     LDACDALLKLGYGSPSLCYAMGGSAGGMLMGVAINQRPELFHGVIAQVPFVDVVTTML
                     DESIPLTTGEFEEWGNPQDPQYYEYMKSYSPYDNVTAQAYPHLLVTTGLHDSQVQYWE
                     PAKWVAKLRELKTDDHLLLLCTDMDSGHGGKSGRFKSYEGVAMEYAFLVALAQGTLPA
                     TPAD"
     gene            complement(20882..21541)
                     /locus_tag="RHX21_001965"
     CDS             complement(20882..21541)
                     /locus_tag="RHX21_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance TerB family protein"
                     /protein_id="HDV1987147.1"
                     /translation="MANWLNQLQSLLGQSSSSTSSSADQGLGKLLVPGALGGLAGLLV
                     ANKSARKLLTKYGTNALLVGGGAVAGTVLWNKYKDKIRAAHQDEPQFGAQSTPLDERT
                     ERLILALVFAAKSDGHIDAKERAAIDQQLREAGVEEQGRVLIEQAIEQPLDPQRLATG
                     VRNEEEALEIYFLSCAAIDIDHFMERSYLNALGDALKIPQDVRDGIERDLEQQKRTLA
                     E"
     gene            complement(21868..22224)
                     /locus_tag="RHX21_001966"
     CDS             complement(21868..22224)
                     /locus_tag="RHX21_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310584.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YebF"
                     /protein_id="HDV1987148.1"
                     /translation="MKKRGAFLGLLLVSACASVFAANNETSKSVTFPKCEGLDAAGIA
                     ASVKRDYQQNRVARWADDQKIVGQADPVAWVSLQDIQGKDDKWSVPLTVRGKSADIHY
                     QVSVDCKAGMAEYQRR"
     gene            complement(22291..22581)
                     /gene="yebG"
                     /locus_tag="RHX21_001967"
     CDS             complement(22291..22581)
                     /gene="yebG"
                     /locus_tag="RHX21_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein YebG"
                     /protein_id="HDV1987149.1"
                     /translation="MAVEVKYVVIREGEEKMSFTSKKEADAYDKMLDTADLLDTWLTN
                     SPVQMEDEQREALSLWLAEQKDVLSTILKTGKLPSPQVVGAESEEEDASHAA"
     gene            22715..23893
                     /gene="purT"
                     /locus_tag="RHX21_001968"
     CDS             22715..23893
                     /gene="purT"
                     /locus_tag="RHX21_001968"
                     /EC_number="2.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent phosphoribosylglycinamide
                     formyltransferase"
                     /protein_id="HDV1987150.1"
                     /translation="MTLLGTALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRY
                     ADAPAMHVAHRSHVINMLDGDALRRVVELEKPHYIVPEIEAIATDMLIQLEEEGLNVV
                     PCARATKLTMNREGIRRLAAEELQLPTSTYRFADSESLFREAVAAIGYPCIVKPVMSS
                     SGKGQTFIRSAEQLAQAWEYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFC
                     APVGHRQEDGDYRESWQPQQMSPLALERAQEIARKVVLALGGYGLFGVELFVCGDEVI
                     FSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGLPVGGIRQYGPAASAVILPQLTSQN
                     VTFDNVQNAVGADLQIRLFGKPEIDGSRRLGVALATAESVVDAIERAKHAAGQVKVQG
                     "
     gene            complement(23949..24590)
                     /gene="kdgA"
                     /locus_tag="RHX21_001969"
                     /gene_synonym="eda"
     CDS             complement(23949..24590)
                     /gene="kdgA"
                     /locus_tag="RHX21_001969"
                     /gene_synonym="eda"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HDV1987151.1"
                     /translation="MKNWKTSAESILTTGPVVPVIVVKKLEHAVPMAKALVAGGVRVL
                     EVTLRTECAVDAIRAIAKEVPEAIVGAGTVLNPQQLAEVTEAGAQFAISPGLTEPLLK
                     AATEGTIPLIPGISTVSELMLGMDYGLKEFKFFPAEANGGVKALQAIAGPFSQVRFCP
                     TGGISPANYRDYLALKSVLCIGGSWLVPADALEAGDYDRITKLAREAVEGAKL"
     gene            complement(24627..26438)
                     /gene="edd"
                     /locus_tag="RHX21_001970"
     CDS             complement(24627..26438)
                     /gene="edd"
                     /locus_tag="RHX21_001970"
                     /EC_number="4.2.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydratase"
                     /protein_id="HDV1987152.1"
                     /translation="MNPQLLRVTNRIIERSRETRSAYLARIEQAKTSTVHRSQLACGN
                     LAHGFAACQPEDKASLKSMLRNNIAIITSYNDMLSAHQPYEHYPEIIRKALHEANAVG
                     QVAGGVPAMCDGVTQGQDGMELSLLSREVIAMSAAVGLSHNMFDGALFLGVCDKIVPG
                     LTMAALSFGHLPAVFVPSGPMASGLPNKEKVRIRQLYAEGKVDRMALLESEAASYHAP
                     GTCTFYGTANTNQMVVEFMGMQLPGSSFVHPDSPLRDALTAAAARQVTRMTGNGNEWM
                     PIGKMIDEKVVVNGIVALLATGGSTNHTMHLVAMARAAGIQINWDDFSDLSDVVPLMA
                     RLYPNGPADINHFQAAGGVPVLVRELLKAGLLHEDVNTVAGFGLSRYTLEPWLNNGEL
                     DWREGAEKSLDSNVIASFEQPFSHHGGTKVLSGNLGRAVMKTSAVPVENQVIEAPAVV
                     FESQHDVMPAFEAGLLDRDCVVVVRHQGPKANGMPELHKLMPPLGVLLDRCFKIALVT
                     DGRLSGASGKVPSAIHVTPEAYDGGLLAKVRDGDIIRVNGQTGELTLLVDEAELAARE
                     PHIPDLSASRVGTGRELFSALREKLSGAEQGATCITF"
     gene            complement(26673..28148)
                     /gene="zwf"
                     /locus_tag="RHX21_001971"
     CDS             complement(26673..28148)
                     /gene="zwf"
                     /locus_tag="RHX21_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HDV1987153.1"
                     /translation="MAVTQTAQACDLVIFGAKGDLARRKLLPSLYQLEKAGQLNPDTR
                     IIGVGRADWDKAAYTKVVREALETFMKETIDEGLWDTLSARLDFCNLDVNDTAAFSRL
                     GAMLDQKNRITINYFAMPPSTFGAICKGLGEAKLNAKPARVVMEKPLGTSLATSQEIN
                     DQVGEYFEECQVYRIDHYLGKETVLNLLALRFANSLFVNNWDNRTIDHVEITVAEEVG
                     IEGRWGYFDKAGQMRDMIQNHLLQILCMIAMSPPSDLSADSIRDEKVKVLKSLRRIDR
                     SNVREKTVRGQYTAGFAQGKKVPGYLEEEGANKSSNTETFVAIRVDIDNWRWAGVPFY
                     LRTGKRLPTKCSEVVVYFKTPELNLFKESWQDLPQNKLTIRLQPDEGVDIQVLNKVPG
                     LDHKHNLQITKLDLSYSETFNQTHLADAYERLLLETMRGIQALFVRRDEVEEAWKWVD
                     SITEAWAMDNDAPKPYQAGTWGPVASVAMITRDGRSWNEFE"
     gene            28486..29355
                     /gene="hexR"
                     /locus_tag="RHX21_001972"
                     /gene_synonym="yebK"
     CDS             28486..29355
                     /gene="hexR"
                     /locus_tag="RHX21_001972"
                     /gene_synonym="yebK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator HexR"
                     /protein_id="HDV1987154.1"
                     /translation="MNMLEKIQSQLEHLSKSERKVAEVILASPDNAIHSSIAAMALEA
                     NVSEPTVNRFCRSMDTRGFPDFKLHLAQSLANGTPYVNRNVNEDDSVESYTGKIFESA
                     MATLDHVRHSLDKSAINRAVDLLTQAKKIAFFGLGSSAAVAHDAMNKFFRFNVPVVYS
                     DDIVLQRMSCMNCSDGDVVVLISHTGRTKNLVELAQLARENDAMVIALTSAGTPLARE
                     ATLAITLDVPEDTDIYMPMVSRLAQLTVIDVLATGFTLRRGAKFRDNLKRVKEALKES
                     RFDKQLLNLSDDR"
     gene            29483..30925
                     /gene="pyk"
                     /locus_tag="RHX21_001973"
     CDS             29483..30925
                     /gene="pyk"
                     /locus_tag="RHX21_001973"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HDV1987155.1"
                     /translation="MSRRLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSP
                     EDHKMRADKVREIAAKLGRHVAILGDLQGPKIRVSTFKEGKVFLNIGDKFLLDANLGK
                     GEGDKEKVGIDYKGLPADVVPGDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNK
                     GINKLGGGLSAEALTEKDKADIKTAALIGVDYLAVSFPRCGEDLNYARRLARDAGCDA
                     KIVAKVERAEAVCSQDAMDDIILASDVVMVARGDLGVEIGDPELVGIQKALIRRARQL
                     NRAVITATQMMESMITNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQYPSETVAAM
                     ARVCLGAEKIPSINVSKHRLDVQFDNVEEAIAMSAMYAANHLKGVTAIITMTESGRTA
                     LMTSRISSGLPIFAMSRHERTLNLTALYRGVTPVHFDSANDGVAAASEAVNLLRDKGY
                     LMSGDLVIVTQGDVMSTVGSTNTTRILTVE"
     gene            complement(31056..32027)
                     /gene="lpxM"
                     /locus_tag="RHX21_001974"
                     /gene_synonym="msbB"
     CDS             complement(31056..32027)
                     /gene="lpxM"
                     /locus_tag="RHX21_001974"
                     /gene_synonym="msbB"
                     /EC_number="2.3.1.243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416369.1"
                     /note="LpxM is lauroyl-Kdo(2)-lipid IV(A)
                     myristoyltransferase, an enzyme characterized in
                     Escherichia coli and involved in biosynthesis of the form
                     of lipid A found in that species and some closely related
                     species; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase"
                     /protein_id="HDV1987156.1"
                     /translation="METKKNNSEYIPEFDKSFRHPRYWGAWLGVAAMAGIALTPPKFR
                     DPILARLGRFAGRLGKSSRRRALINLSLCFPERSEAEREAIVDEMFATAPQAMAMMAE
                     LAIRGPEKIQPRVDWQGLEIIEEMRRNNEKVIFLVPHGWAVDIPAMLMASQGQKMAAM
                     FHNQGNPVFDYVWNTVRRRFGGRLHARNDGIKPFIQSVRQGYWGYYLPDQDHGPEHSE
                     FVDFFATYKATLPAIGRLMKVCRARVVPLFPIYDGKTHRLTIQVRPPMDDLLEADDHT
                     IARRMNEEVEIFVGPRPEQYTWILKLLKTRKPGEIQPYKRKDLYPIK"
     gene            complement(32147..33469)
                     /gene="mepM"
                     /locus_tag="RHX21_001975"
     CDS             complement(32147..33469)
                     /gene="mepM"
                     /locus_tag="RHX21_001975"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein DD-endopeptidase MepM"
                     /protein_id="HDV1987157.1"
                     /translation="MQQIARSVALAFNNLPRPHRVMLGSLTVLTLAVAVWRPYVYHRD
                     ATPIVKTIELEQNEIRSLLPEASEPIDQAAQEDEAIPQDELDDKIAGEAGVHEYVVST
                     GDTLSSILNQYGIDMGDITQLAAADKELRNLKIGQQLSWTLTADGELQRLTWEVSRRE
                     TRTYDRTAANGFKMTSEMQQGEWVNNLLKGTVGGSFVASARNAGLTSAEVSAVIKAMQ
                     WQMDFRKLKKGDEFAVLMSREMLDGKREQSQLLGVRLRSEGKDYYAIRAEDGKFYDRN
                     GTGLAKGFLRFPTAKQFRISSNFNPRRTNPVTGRVAPHRGVDFAMPQGTPVLSVGDGE
                     VVVAKRSGAAGYYVAIRHGRSYTTRYMHLRKILVKPGQKVKRGDRIALSGNTGRSTGP
                     HLHYEVWINQQAVNPLTAKLPRTEGLTGSDRREFLAQAKEIVPQLRFD"
     gene            complement(33485..34417)
                     /gene="znuA"
                     /locus_tag="RHX21_001976"
     CDS             complement(33485..34417)
                     /gene="znuA"
                     /locus_tag="RHX21_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416371.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     ZnuA"
                     /protein_id="HDV1987158.1"
                     /translation="MLHKKTLLFAALSAALWGGATQAADAAVVASLKPVGFIASAIAD
                     GVTETEVLLPDGASEHDYSLRPSDVKRLQNADLVVWVGPEMEAFMQKPVSKLPEAKQV
                     TIAQLEDVKPLLMKSIHGDDDDHDHAEKSDEDHHHGDFNMHLWLSPEIARATAVAIHG
                     KLVELMPQSRAKLDANLKDFEAQLASTETQVGNELAPLKGKGYFVFHDAYGYFEKQFG
                     LTPLGHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVVESVARGTSVRMG
                     TLDPLGTNIKLGKTSYSEFLSQLANQYASCLKGD"
     gene            34496..35251
                     /gene="znuC"
                     /locus_tag="RHX21_001977"
     CDS             34496..35251
                     /gene="znuC"
                     /locus_tag="RHX21_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter ATP-binding protein ZnuC"
                     /protein_id="HDV1987159.1"
                     /translation="MTSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKS
                     TLVRVVLGLVTPDEGVIKRNGKLRIGYVPQKLYLDTTLPLTVNRFLRLRPGTHKEDIL
                     PALKRVQAGHLINAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALY
                     DLIDQLRRELDCGVLMVSHDLHLVMAKTDEVLCLNHHICCSGTPEVVSLHPEFISMFG
                     PRGAEQLGIYRHHHNHRHDLQGRIVLRRGNDRS"
     gene            35248..36033
                     /gene="znuB"
                     /locus_tag="RHX21_001978"
     CDS             35248..36033
                     /gene="znuB"
                     /locus_tag="RHX21_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter permease subunit ZnuB"
                     /protein_id="HDV1987160.1"
                     /translation="MIELLFPGWLAGIMLACAAGPLGSFVVWRRMSYFGDTLAHASLL
                     GVAFGLLLDVNPFYAVIAVTLLLAGGLVWLEKRPQLAIDTLLGIMAHSALSLGLVVVS
                     LMSNIRVDLMAYLFGDLLAVTPEDLIAIAIGVVIVVAILFWQWRNLLSMTISPDLAFV
                     DGVKLQRVKLLLMLVTALTIGVAMKFVGALIITSLLIIPAATARRFARTPEQMAGVAV
                     LVGMVAVTGGLTFSAFYDTPAGPSVVLCAALLFILSMMKKQAS"
     gene            complement(36180..37190)
                     /gene="ruvB"
                     /locus_tag="RHX21_001979"
     CDS             complement(36180..37190)
                     /gene="ruvB"
                     /locus_tag="RHX21_001979"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HDV1987161.1"
                     /translation="MIEADRLISAGTTLPEDVADRAIRPKLLEEYVGQPQVRSQMEIF
                     IKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLT
                     NLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGA
                     TTRAGSLTSPLRDRFGIVQRLEFYQVPDLQYIVSRSARFMGLEMSDDGALEVARRARG
                     TPRIANRLLRRVRDFAEVKHDGTISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKF
                     FGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATTRAWNHFGITPPE
                     MP"
     gene            complement(37199..37810)
                     /gene="ruvA"
                     /locus_tag="RHX21_001980"
     CDS             complement(37199..37810)
                     /gene="ruvA"
                     /locus_tag="RHX21_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012131997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HDV1987162.1"
                     /translation="MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQE
                     AIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAV
                     EREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATDDAE
                     QEAVAALVALGYKPQEASRMVSKIARPDASSETLIREALRAAL"
     gene            complement(37949..38014)
                     /gene="yobI"
                     /locus_tag="RHX21_001981"
     CDS             complement(37949..38014)
                     /gene="yobI"
                     /locus_tag="RHX21_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response small protein YobI"
                     /protein_id="HDV1987163.1"
                     /translation="MYIFITHFFTEYVIFKYLLPI"
BASE COUNT         9127 a         9791 c         9369 g         9734 t
ORIGIN      
        1 gttttaattt gaagcagttg caccatgata gtgcgtataa tcaggatgaa ttgagtaacc
       61 cttcaacgac ggggttactc aagattgagg aaggattatc gttcggcgac cagacgaata
      121 atatcgtcgt cttcaaccga tttttgactc tcaatggtct ttttatctgc tttctctggt
      181 tcgtttgctt cgcacaaacg acgtaacagt gcattttgac gtttttgctg atccagcaac
      241 gcctcaagca gttcaatctg ttcgttagtc cgagaactgg cacgattaat aaaaaaccac
      301 aagatgagcc cgataagaag aaccaccacc gatacaacca aagacgcaat gttcatcacg
      361 cctgaattta caacttcgtt catttcacca cctctgagta gaggcgctat tctaccactg
      421 ctggagagga agaaaatcta gtgctgaaaa aatgatatca ccacgggata aactggttaa
      481 tggcacaaat tccgctgaaa aattgtacat cctgatcgca catcatgttg aatacctgcg
      541 cccaaagcag caagcaagcc aacaccacga caaccagaac gacccatcga aactttttca
      601 ctccaatctc cgtttcacct accttatgtc attaaactag catgcgttag ttaaacagcg
      661 cctaactatg tcgatattcg tgctttttcg gaatgagtcg cttgcttcag cgcatattgc
      721 cgctacgatt aagcgaacat aaaaagagaa gaggttgtaa tgcgattcat cattcgcaca
      781 gttatgctga tagcactggt atggatagga ttattactca gcggatatgg cgttttgatt
      841 ggaagcaaag agaatgccgc aggattaggt ttgcaatgta cctatctgac tgccagaggc
      901 accagcacgg tacaatactt gcacactaaa agtggtttct tggggataac agattgccca
      961 ctgttacgta aaagcaatat cgtggtcgat aatggttaag ggtaataaat aaccagatcc
     1021 tcactcatga gtaaaatatt cttatagcaa gcgcgtttaa tataacgcac cttcaacttt
     1081 atttttctca tgctaaataa agaacctgtc tgtttgatat tccgacaggt tcttactctc
     1141 atcagaacgg atagtcgtga taacccattt gggcagaaat tttgcgcgct gcggtatgca
     1201 acattgcgac atattcctgt aaacgctctt cagagaaacg caacgtcggg aaggagatgc
     1261 tcaaaccggc aatgaccacg ccaaagcgat caaataccgg taccgcaatg catcgcagcc
     1321 cttcttcctg ctcttcgtta tcttcgccat acccctgctc gcgcacctgg tccagaacgg
     1381 gtaataacgc ttctgtactg gtgatggtcc gctcggtact gcgtttatac tccacgccct
     1441 caagaatttg cttcacttca tcgagatcgc gccatgccag cagtacctta ccaatcgcgg
     1501 tgctgtacag cggattacga cgcccaatcc gtgaatacat gcgcaaattg tacatagagt
     1561 caattttgtg aatgtaaaca atactgtctt cgtccagtgc gccgaggtgg atagtttctt
     1621 tggtcaggcg ggagatctca cgcatctgga tatctgcgct acgaattaaa tcgacgtttt
     1681 gtaacgcgcg agcgcccagt tcaaacaatt tcagggtcag ggaatatttc tccgactccc
     1741 cttcctgcgc cacataacct aaggttttca tggtctgtaa aaagcgataa acggtgcttt
     1801 ttgacatcat gacgcgctgc gacagctcgg ttatccctat ttcgcgctct tcacccagcg
     1861 cctgcaaaat gccaaaaact tttagcacgg aagatacaga atcaggctgt ttatccagat
     1921 ctgcgttagc catttatcac ctcattgcga gtgttttata aaaatcagaa ctgtttttta
     1981 ttataatttc gcaccagggt ggtcgcaatc catcttttgc cggttagtta caattctgcg
     2041 acatccaccg tgaatatcag tgctagaatc atacccctgt tgattattca ccaaagatat
     2101 aaaattccta tgccaaaagt tcaggccgac ggcctgccat tgccccagcg atacggtgcg
     2161 atattaacca ttgtgattgg tatttcgatg gctgtccttg acggcgcaat cgccaacgtc
     2221 gccctgccaa caatcgccac ggaccttcat gccacgccag ccagttccat ctgggtagtg
     2281 aacgcctatc aaatcgccat tgtcatctcc ctgctctcgt tttcgtttct gggcgatatg
     2341 tttggctatc gacgtattta taaatgcggt ctggtcgttt ttctgttgtc ttcactgttc
     2401 tgcgcccttt ctgattcgct gcaaatgctc acccttgcgc gtgtcataca aggtttcggc
     2461 ggtgcagcgt tgatgagcgt taataccgca cttatccgcc tgatctatcc acaacgtttt
     2521 ctggggagag ggatgggcat aaactcgttt attgttgccg tttcttctgc tgccgggccg
     2581 acaattgctg cagcaatcct ctccatcgca tcctggaaat ggttattttt aatcaacgta
     2641 ccgttaggta ttatcgccct gcttctggcg atgcgttttc tgccacccaa tggttctcgc
     2701 gccagtaaac cccgtttcga cctgcccagc gccgtgatga acgcgttaac cttcggcctg
     2761 cttatcactg cgttgagtgg tttcgctcag gggcaatcgc tgacgttaat tgctgcggaa
     2821 ctggtggtaa tggttgttgt tggtattttc tttattcgcc gccagctttc tcttcccgta
     2881 ccgctgctac cggtggattt actgcgtatc ccgctgtttt cactttctat ttgcacatct
     2941 gtttgctctt tctgcgcaca aatgctggca atggtttccc tgccctttta cctgcaaacc
     3001 gtgctcgggc gtagtgaagt cgaaacaggt ttacttctga caccgtggcc gttagcaacg
     3061 atggtgatgg ctccgttggc aggctatttg attgaacgcg tacatgcagg attgctgggt
     3121 gctctagggt tgttcatcat ggctgcgggg cttttttccc tggttctgct gcccgcgtca
     3181 cctgcggata tcaatattat ctggccgatg atcttatgtg gcgctggatt tggcttgttc
     3241 cagtcaccca ataaccacac cattattacc tccgctcctc gcgaacgtag cggtggagcc
     3301 agtggcatgt taggaacggc tcgtctactg ggtcagagta gcggcgcggc actggtggcg
     3361 ctgatgctaa atcagttcgg tgataatggt acgcacgttt cgctgatggc tgcggctatt
     3421 ctgacagtga ttgctgcctg tgtcagtggt ttacgtatca ctcagccacg atccagggca
     3481 taaaaaaagc gcgtcgatca ggacgcgctt tttagtattt acttcatatt acttcaggta
     3541 ttcacccgta cgcagagctt caattcgttt atccagcggc gggtgagtca tgaacaactc
     3601 actgagcgat ttcgacttac cgttaatgca gaaagccatc atgctggttg cttcttgcgg
     3661 ttcatagctg gttttcaggc gctgcagcgc ggcaatcatt ttctcgcgac caaccagttt
     3721 tgccgaaccg gcatcagcat ggaattcacg atgacgcgag aaccacatgg tgataatgct
     3781 cgccagaata ccaaacacca gttccagaac cgttgcaacc gcaaagtaga tcagcgggtt
     3841 gccgttgctc tcttcacctt catcacgatt tccgcccata aaacccgcgg caagctgcgc
     3901 cagaatacgg gaaataaaga taacgaaggt gttcaccacg ccctgaatca gcgtcatggt
     3961 gaccatatca ccattggcga tgtggctgat ttcgtgagca attaccgcct cggcttcatc
     4021 cgggctcatg ttctgcagca aaccggtgct gacagcaacc agagaggcat cacggcgcgc
     4081 accggttgca aaagcgttga tgtccggcgc atggtagata gccacttgcg gcatagcgat
     4141 ccctgcctga cgagcctggg ttgctacagt attaaccagc caacgttccc tttcgttacg
     4201 cggttgctcg atcacttccc cgccaacaga tcgtaatgcc atccatttgg acatcagaag
     4261 cgaaacgaag gaaccaccaa aaccgaacag caaggccatg atcatcagcc cctgaacgct
     4321 gctcgactgt atccctgtca ggctcagtac cagcccgaaa acgaccatta cggccaggtt
     4381 cgttagcagg aagagcgcga ttcgcatcat aattttcttt ttacctcagt ttaacaaaac
     4441 gcaatatgcg atacccacat cgtatgggtt acgcgactat tttcaagtct ggatagtgcg
     4501 taagtcacca gaaagacaca actttacatt ttgtagcatc tgatttacgg catcttgccg
     4561 ctgttaaaaa atcaggcaca atttcttgtg cctgattgat attacttgac gggagcgggt
     4621 tgttccgcgg gtctggcttt ttcaagcttc gccagatcga gtgcgatatt caccgtctca
     4681 tccagataag gatccggctc ctggtaatct ttcggtagat catccagctt cttcaactcc
     4741 ggtttacctt cgcgtttaaa gcgttcgttc aaacgcgcca gacgcgtcgc atcatcttca
     4801 ttattctctt tctcacgcac agcgtagttc agagaaacga tattgcgctt gtccttcata
     4861 gcgttgaagc gcgcgatatc cttcatgatg ttctggaact caggatcttt cgcgatacgc
     4921 gcattatgtt ccttcagcag ctccggccca aaggccgtta aatcgcctga tttcacataa
     4981 gtcgcggcat caatgctatc ccacggcagc gcgttatctt cgaatttctc acccgtttcc
     5041 gtttcttcat tacccgtcgg catgatgatg tctggcgtta cgcctttacg ttgcgtactg
     5101 ccgccgttaa cgcgatagaa tttctggatc gtgtactgca cagaacccag cgctggccat
     5161 tcaggacgta acatctgatc gtaaatacgg ttcaatgaac ggtattgctg aacggtgcct
     5221 ttaccaaacg tcggttcacc cacaaccagc gcacgaccgt aatcctgcat tgccgcggca
     5281 aagatttctg aagccgaagc actgaaacgg tcaaccagta ccaccagcgg gcctttatag
     5341 aacacctgcc cgtcggtatc gctgtcttca cgaaccttgc cgttgttatc gcggacctga
     5401 acaatgggac ccgcaggaat aaacagacct gagagcgata ccgcttcggt caacgcccca
     5461 ccgccattgc tacgcaggtc gatgatcaca ctgctgacat tctgtttttc cagtttctgc
     5521 agttgaactt tgacatcgtc tgtcaaaccc acatagaagc ccggaatatc cagcacgccg
     5581 actttctctt taccgacggt cttcaccgac attttaaccg cgcggtcttc gagacgaata
     5641 cgttcacggg tcaatgttac agtgcgggtc ttggtccctt taccagcagg taaaatttcc
     5701 agacgaactt tactgccctt cggcccttta attaaggcaa ccacatcatc aagacgccag
     5761 ccaatcacgt caaccatcgg cttgcctgtt tgaccaacac cgacaatttt gtcaccaacg
     5821 ctgatagctt tactcttcgc tgccggacca cctgccacca tcgaattgat aacggtgtag
     5881 tcatcatcca tttgcagcac tgcgccaata ccttccagcg acaaactcat ttcagtgttg
     5941 aactgttcgg tattacgcgg ggaaagatag ttggtatgcg ggtcgatttc acgcgcaaac
     6001 gccgtcattg ccagcgagaa aacatcttcg ctgttggttt gcgccagacg acgaatggca
     6061 aatttgtagc ggcgtgtcag ggtttcacga atttctttat ccgtttttcc tgccagcttc
     6121 aggcttaact cgtcgaattt gactttactg tcccacagcg cgttcaactc agcctcgttt
     6181 ttcggccagg gcgctttgct gcggtcaagg ttataagtgt cgttgccggt gaaatccatc
     6241 ggcttttcca gtaccgacaa agcgtactgg taacgctcaa aacggcgctt ttgcgccaga
     6301 ttgtagagat cgtagaaaac gtcgagtttg cctgaacgca gttcatcgcc taactcggtt
     6361 ttctttttcg cgaactgttc aacatcgctt gccagcagca cgttgtggct gtaatcgagc
     6421 agattcaggt agcggtcaaa gattttggcc gaaaatgcct gatcgaggtc gaactggcga
     6481 taatgagaac gggtgaagcg cgacgttacg cgctcactta ccgtcgcatg ctgcgtctct
     6541 tcctttaata ccggaatttg atcagcacgc gtgatatctt ctacagcgaa ggtctggcct
     6601 gctattgcaa gcaggccagc taacgcggta agcctaaaaa acatgttcat gcctggcccg
     6661 gcctccgttt cagaacacca ggtgttctgc gcgcacaatc aaagacatac ccgaattcag
     6721 ctggacgcgg acgccgtctt tggtgatttc taatacggtg gcatccatcg cgttttgacc
     6781 cgctttcacc ttcagggctt gtccgacagt cagagctgaa atgtcagaaa ccggggtgtg
     6841 ctgttcttcg cgaggtgctt ttactgtttt tggcgctttc tctaccggct tttgcgcacg
     6901 aggtttacgt tcagcgcctt ctttgcggcg tggcgtggtc ggacgtggct tgcgttcgcg
     6961 gcgcggtgcg tcttctttct caccagcagc tgcggcagct tcgcgttttt tcgcttgctg
     7021 ttcagcacgc tgtgcctgaa cacgcgcttt cgcttcttca agctgcttgc gagcatgctc
     7081 tacatgttgc tcgtccagct caccgcatgg gttgccgtca agatcgacac gcgttgcgcc
     7141 gggtttaaca ccgtaaagat aacgccagct cgaagtgtag agacgtaaag cggatcgtaa
     7201 ttgcgttttg ctcaggttca tttccccggc aacacgatcg accaaatcct gaaaaatacc
     7261 gattttcagc ggacgcgctt caccttccgc actgaaacag tggggaaaac gttcggccag
     7321 aaacgcgatt acttctttac tgctattcaa cttaggttga ttttccatga aatttcctga
     7381 ttacaacgga cgtagccaac aagcgcaggc atgaacaggc gtcattataa tgacgctacc
     7441 agtaaatgct acgttatccg ttgattatcc tgcgacgctc gcaaagaatt ttttgtaatc
     7501 cgtcgttgca agcacttttt caagctgtgc cacaagctga cgtaagcctt gctcgtcctc
     7561 gtctgtaaag cgaccgaaga cggtactatc gatgtcaaga acaccaataa tctgattttt
     7621 caccaccagc ggcagaacaa tttcagaatt actcgccgca tcacaggcaa tatgcccgtc
     7681 aaacgcgtga acatcctcga tacgctgcac ttgattgcgg gcaaccgcag tgccgcacac
     7741 cccgcgcccg acgggtatcc ggacacaggc aattttgccc tgaaatggtc cgagtaccag
     7801 tgtatcgtcc tcaagcaaat aaaaacctgc ccagtttacg tcagtgagac gctcgtataa
     7861 caacgcactg gtgttcgcaa gcgttgccag aaaactggtt tctcccgcca tcagcgcgtt
     7921 aaagtcgcga tttaaatccg cgtaaaattc tgttttgttc attatataat cacttgtttg
     7981 tcttacctgg aactgccagc ctattaaaat aagcattaaa tgcgttaatg ctcaagatca
     8041 ttcccatcat gggttaagat taatgttaat tcttattaca tttggcacgt catggctctt
     8101 aacacaccac aaattacgcc gacaaaaaag ataacagtga gggcaatcgg cgaggaactg
     8161 ccgcgtggtg attaccaacg ttgcccgcaa tgtgacatgc tgtttagcct gcccgagata
     8221 aattctcatc agagtgccta ttgtccgcgc tgtcaggcaa aaattcgcga cgggcgcgac
     8281 tggtcgctaa cgcgcctggc ggcaatggct ttcaccatgc tgttgctgat gccgtttgcc
     8341 tggggcgaac cgctgttgca tatctggctg ttaggtattc gtatcgacgc caacgtcatg
     8401 caaggcatct ggcaaatgac caaacagggc gatacgataa cgggggcgat ggtctttttc
     8461 tgcgttattg gtgcccccct cattctggtg tcctccatag catatttatg gtttggtaac
     8521 cgactgggaa tgaatttacg tccggtactg ctgatgcttg agcgacttaa agagtgggta
     8581 atgctggata tctacctggt cggcattggc gttgcttcta taaaggtaca ggattatgcc
     8641 catatccagg cgggtgtcgg cttgttctct tttgtggcgt tggtgatttt aacgacggtg
     8701 acgttgtcac atcttaatgt cgaggagctg tgggagcgat tttatccgca gcgccccgct
     8761 acgcgtaggg acgagaaact tcgtgtctgt cttgggtgcc attttaccgg ctatcctgat
     8821 cagcgtggtc gctgcccgcg ttgccatatc ccgctacgcc tgcgtcgccg tcatagtttg
     8881 caaaaatgct gggcggcgct gttagcgtca atcgttttgt tgttacctgc caacctgttg
     8941 cctatttcta tcatttatct gaacggagga cggcaggaag atacaattct ttccggaatt
     9001 atgtcgctgg caagtagcaa cattgcggtt gcgggaatcg tgtttatcgc cagtattctg
     9061 gtaccgttta ctaaagtgat cgtcatgttc actttactgt tgagcattca ttttaaatgc
     9121 cagcaaggtt tacgcacacg cattctgtta ctgcggatgg tgacctggat tggtcgctgg
     9181 tcgatgctcg acctgtttgt catatcttta accatgtcgc tgattaatcg cgatcagatc
     9241 ctcgctttta ctatgggacc ggctgcgttt tattttggcg cagccgtaat tttgactatt
     9301 cttgctgtgg aatggctgga cagccgctta ctttgggatg cacatgagtc aggaaacgcc
     9361 cgcttcgacg actgaagcgc agattaaaaa taaacgccgt atctcacctt tctggctgct
     9421 gcctttcatc gcgctaatga ttgccggttg gctgatttgg gacagttatc aggaccgggg
     9481 taataccgtc accatcgact ttatgtcggc ggatggtatt gtcccgggcc gtacgcctgt
     9541 tcgttatcag ggcgttgaag tcggaacagt gcaggatatc agcctcagcg acgatcttcg
     9601 taagattgaa gtcaaggtca gcatcaagtc cgatatgaaa gatgcgctgc gcgaagagac
     9661 tcaattctgg ctggtgacgc caaaagcatc gttggcaggt gtctctgggc tggacgccct
     9721 cgtcggtggg aactatatcg gcatgatgcc gggtaaaggt aaagagcagg atcactttgt
     9781 cgcactcgat acccaaccga aatatcggct ggacaatggc gatctgatga tccacctgca
     9841 agcccccgat ctcggttcgc tgaacagcgg ttcattggtc tatttccgca agatcccggt
     9901 gggaaaagtc tacgactatg ccatcaatcc caacaaacaa ggcgtggtga ttgatgtcct
     9961 gatcgagcgg cgttttaccg atctggtgaa aaaaggtagc cgtttctgga acgtttccgg
    10021 cgttgatgcc aatgtcagta tcagtggcgc gaaggtgaaa ctggaaagcc tggcggcact
    10081 ggttaacggt gcgattgcct tcgattcacc agaagagtcg aaacctgccg aggcggaaga
    10141 tacctttggt ctgtatgaag acctcgccca tagccagcgt ggcgtaataa taaaactgga
    10201 actgccgagt ggggccggat taaccgccga ctcgacgcca ttaatgtatc agggactgga
    10261 agtcggacag ctaactaaac tggatttaaa tcctggtggt aaagtcactg gggaaatgac
    10321 agttgatccc agcgtcgtta ccctgcttcg tgaaaatacc cgcatcgaat tacgtaatcc
    10381 gaaattatcc cttagcgatg ccaatctcag cgccctgctg actggcaaaa ccttcgagtt
    10441 ggtacccggc gatggcgagc cacgcaaaga gttcgttgtt gtgccaggcg aaaaagcact
    10501 gctgcatgaa cctgatgttc tgacgctgac cctgaccgcg ccggaaagtt acggtattga
    10561 tgctggtcag ccgctcattc ttcacggcgt gcaggtaggc caggttatcg atcgtaaact
    10621 caccagcaaa ggcgtcacct ttaccgtcgc catcgagcct cagcatcgag aactggtaaa
    10681 aggcgatagc aaatttgtcg tcaacagccg tgtcgacgtg aaggtggggc tggatggcgt
    10741 tgagtttctc ggtgccagcg cctcagaatg gattaacggc gggatacgta ttctgccggg
    10801 cgataaaggc gagatgaaag ccagctatcc actgtatgcc aatctggaaa aagcgctgga
    10861 gaacagcctt agcgatttac ccaccacaac cgtgagtttg agtgcagaga cgctgccgga
    10921 tgtgcaggca ggatcggtag tgctgtaccg taaatttgaa gttggtgaag ttattaccgt
    10981 gcgtccgcga gctaacgcgt ttgatatcga tctgcatatt aagccggagt atcgcaacct
    11041 tctgaccagc aatagcgtgt tctgggcaga aggcggggcg aaagttcagc tgaatggtag
    11101 tggcctgacc gtacaggcat ccccgctctc cagagcatta aaaggggcta ttagcttcga
    11161 taacctcagt ggtgccagcg ccagtcagcg taaaggcgac aaacgtattc tgtatgcttc
    11221 cgaaacagcg gcccgtgcgg ttggtgggca gattacgctt cacgctttcg atgccggaaa
    11281 actggcggtc gggatgccaa ttcgctatct cggtattgat atcgggcaaa tccagacgct
    11341 ggatctgatt accgcgcgca atgaagtaca ggcaaaggcg gtgctctatc cggaatatgt
    11401 ccagaccttt gctcgcggtg gtacgcgctt ctcagtggtc acaccgcaaa tttcggcagc
    11461 tggcgttgag catcttgata ctatcctcca gccgtatatc aacgtcgaac caggccgggg
    11521 caatcctcgc cgcgactttg aattacaaga ggccaccatt actgattcgc gttacctgga
    11581 tggcttaagc attattgttg aagcgccgga agccggttcg ttaggtattg gtacgcctgt
    11641 gctgttccgt ggtctggaag tcggtacggt tacaggaatg acgctgggga cattgtcaga
    11701 tcgcgtgatg attgcgatgc gcatcagtaa acgctatcaa cacctggtgc gtaacaattc
    11761 cgtcttctgg ttggcatcgg gttacagtct ggactttggt ctgacgggcg gcgtagtgaa
    11821 aaccggcacc tttaaccagt ttatccgtgg cggcatcgcc ttcgccacgc ctccgggtac
    11881 gccactggca ccgaaagccc aggaaggcaa acacttcctg ttgcaggaaa gtgaaccgaa
    11941 agagtggcgt gaatggggaa ctgcgcttcc caaataatgc ccactgctcc ggcgtgcctg
    12001 cgccggagcg tttatgctaa actgcgcgcc tgtttttttg ccagtggtac atgctcgtgg
    12061 cccaacacac cgtttatttc ccggacgcct ttctgacaca aatgcgcgaa gcgatgcctt
    12121 cgacgctctc atttgatgat tttcttgccg cctgtcagcg cccgttgcgc cgcagcattc
    12181 gcgttaatac gctgaaaatc tccgttgctg atttcctgca attaaccgct ccttatggct
    12241 ggacgcttac gccaattccg tggtgtgaag aaggtttctg gattgaacgc gacaatgaag
    12301 atgcattgcc attgggtagt accgccgagc atttaagcgg cctgttttat attcaggaag
    12361 ccagttcaat gttgcccgtt gccgccttgt ttgctgacga taatgcacca cagcgggtga
    12421 tggatgtcgc agctgcgcca ggctccaaaa cgacgcaaat tgccgcgcgg atgaataacg
    12481 aaggggcaat ccttgccaat gagttttccg ccagtcgggt aaaagtgtta catgccaata
    12541 tcagccgctg tggcatcagt aatgttgcgc tcacacattt tgatggccgc gtgtttggtg
    12601 cggcagtgcc agaaatgttc gatgccattt tgctggacgc tccctgctct ggcgaaggcg
    12661 tggtgcgtaa agatcccgat gcgctaaaaa actggtcacc agaaagcaat caggaaatcg
    12721 cagctacaca acgggagctt atcgacagcg cctttcatgc attacgtcct ggtggtacgc
    12781 tggtttactc gacctgtacc ttaaaccagg aagaaaacga agccgtttgc ctgtggctga
    12841 aagagactta ccccgacgca gtagagtttt taccacttgg cgatctcttc cctggtgcaa
    12901 acaaagcgct gaccgaagaa ggctttttgc atgttttccc acaaatttac gactgcgaag
    12961 gcttcttcgt tgctcgtctg cgtaaaactc aggcgattcc cgccttaccc gcccccaaat
    13021 acaaagtggg caatttcccg ttcagcccgg tgaaagatcg cgaagctgga caaattcgtc
    13081 aggcggctgc aggtgttggc ttaaactggg atgaaaacct gcgcctctgg cagcgtgaca
    13141 aagaactgtg gttgttcccg gtgggcattg aagccctgat cggtaaagtc cgattttctc
    13201 ggttggggat taaacttgcc gagacgcaca acaaaggtta tcgctggcag catgaagcgg
    13261 ttattgctct tgcctcaccc gataatatga atgcattcga gctgacaccg caggaagcgg
    13321 aggagtggta tcgcgggcgc gatgtttacc cgcaagccgc gccagtggcg gatgatgtat
    13381 tggttacttt ccagcatcaa ccgattggtt tagccaaacg gattggttcg cgattgaaaa
    13441 acagctatcc gcgtgaactg gtgcgcgatg ggaaactttt taccggtaac gcctgacagc
    13501 gcacaaaaaa agcgcacttt ttgactggca cattcggctg cctcaactag gctgaaaaat
    13561 ggtgcgatcg gactggtcgt accacaatcg gcagctaaat ggagagcacg aagatgaaaa
    13621 ccagtgtgcg cataggcgct tttgaaatcg acgacggcga attacacggt gaatcgccag
    13681 gtgatcgaac gttaaccatt ccttgtaaat ctgaccccga tttatgtatg caactggatg
    13741 cctgggatgc tgaaaccagt atccctgccc tgctaaatgg cgaacactct gtcctttacc
    13801 gtacccgtta cgatcaacaa tctgatgcct ggattatgcg tcttgcctga tccaaaaaga
    13861 acccgtcggc atggcgggtt atttgtcctg gttattcccc cgttgtaaaa tctctcctaa
    13921 acttaacggt acggcaccac acttcgggga tgaaatgttc gcgctggtac tttttgtttg
    13981 ctacctggat ggcggttgtg aagatattgt tgtggatgtc tacaacacgg aacagcagtg
    14041 tctttattct atgagcgatc aacggatccg ccatggcggt tgttttccga ttgaggattt
    14101 tatagatggt ttctggcgac cagcacagga gtatggtgat ttttaattat tgcaattgca
    14161 caagagtcag ttcgccccca aagacagcac cggtatcaat ataatgcagg ttgccaatat
    14221 ccacgcgatg tcgcaacggt gtatgaccaa accagaaatg atcagcacct gtaattccct
    14281 gccctttttg gcgttcacct aatcgcgagc ggctccacaa gacctgatgc aaatcaacgt
    14341 ccttttgcca ttcataaaca tcatctggat aatcggcatg agcaataaca tgtttgccgg
    14401 tacgactgtg tacttcaaga ataaagggca aatgctgaca tttttccagc gccgttttcg
    14461 cttgtttctg ttgattatct gccagcgcaa taaaccagtc gccgccattc atcaaccaca
    14521 aagacatctg ctgggatgcc agcgcatcca tcgccatctg ttcatgattg cctcttaccg
    14581 cacaaaccca atgttgttcc agtaactgca gacaacgtaa actttgcggc ccacgatcga
    14641 taacgtctcc tactgagata agtaaatctc gccacggatc aaaacgacaa tgccataatt
    14701 tgcggcgcaa ctgctcaaga caaccgtgta tatcgccaga aagccagata tgtcgccatt
    14761 gatgacccgc aattctctga taaacgggcg caggctgttt catcaatatt ttcctcccgc
    14821 gctaaagatc acataatctt aacaagaatg ttaaaaaacg ctggactcag acagtagagt
    14881 gtgtgttatg gttgactata aagtcagcga aggaaatgct tctggctttt aacagataaa
    14941 aagagaccga acacgattcc tgtattcggt ccagggaaat ggctcttggg agagagccgt
    15001 gcgctaaaag ttggcattaa tgcaggctta gttgccttgc cctttaagaa tagatgacga
    15061 cgccaggttt tccagtttgc gtgcaaaatg gtcaataaaa agcgtggtgg tcatcagctg
    15121 aaatgttaaa aaccgcccgt tctggtgaaa gaactgaggc ggttttttta ttggaaatca
    15181 aaaggctatt ttaggtaatt aacagagttt ttcagctcgt tctataaacg gtgccagact
    15241 cattttttcg ccgggattgt taggatcatc aatctgaatc accgaaatgg gttgggcttt
    15301 agtcttccca ctggcaactt ccttttgtgc gatatcgttt aaaggatact gcacgagggt
    15361 acttgggttg atgacataca aagcattacc cggtcggcaa gtcagcatca cctcttcgcg
    15421 attaaacgcc catttgtctt tacccacttc aaaacggctg acggtaatca cctgcggtgc
    15481 agccagcgcc gctgcagaac tggtgagtaa cagaaacgcc agaatacttt ttttcatcat
    15541 tttcgtaatc catcaaaaag gttcgagagt cgcaagcagg ctgatgatca ccagcactac
    15601 cgcacctatc gcccattcga gtttagtcat ccacacaaac cagggtgccg cacgatcttc
    15661 atcctgcctc atgcgcggta caagaacata acgattagcc agcgcaatga ccaccataat
    15721 catcaccagg atggctttga gcaataagag ttggccccag taagtcgtta gcgtgggggg
    15781 aaatccggta atcaacaatg cattaagcac gccgcttgcc agtacgccga tcaccgcaaa
    15841 atgcccgcac caggaaaaac gcatcagcgc ctgaatagcc tggtgtcgcc aacggccttt
    15901 gatgagttgc atacaccaga gcaccggcag taatccccca aaccacgccg ccgcacaaat
    15961 caggtgaatc gcgtgattag tctgatggat tttcgccgtt accccttcat tcagcgtcgc
    16021 atgcccgatt cccgccagca gaataaattg cgcggtagtg agcataaaca gcaaacgtgg
    16081 catattccgc ggttgcataa gggcgacgat caacgttacg agggcgagaa caatttgcca
    16141 taaccagacg ccaccaaact gcgtttgcaa aacagcctgc caaatgtttg gcgaaaatac
    16201 atctgcccat cccgttccca tcaacccgcc ctgaacggcg agcattgcag tggcactgat
    16261 caaactccag acggcagcgt gctgttgtaa acgcagaaaa cgcttcgcca gcaagcgacg
    16321 aatcgttaag ggggccagcc aggcaccgta cattgcgaag ccaaagacca gcatcagcga
    16381 ggtgaaatgg ataaatcgca gcgcgatcca ggtaaacgcc agcatgattt atttcacgct
    16441 aaaggtgtag tgtcctttcg ttttatgccc gtccaccgaa acaacatgcc agtcaacgat
    16501 gtaggttccg ggtttcagcg aatcggccag tggaacaatc agttgctttt ggtcctgctc
    16561 atttcgcttc gccggtaatg ttttaatatt ttcgtttttt ggccccgtga tttttgcacc
    16621 actgaatcct gtttcaacac cttccgagaa gtttaaagtg attgcctgcg gtgcagctgt
    16681 cacttgcgcg tttgccgcag gatactgatg cgttaaatgc gcatgtgccc agacggaagg
    16741 tgtcaccaac gaagtggtca ggattgccag cgcgtagcga agggagcgtg cagttgaagt
    16801 catattatct attccttttt gtaataactt ttttacagag cataaccttg tctaatgtct
    16861 gagtcgagga tcatcaattc cggcttgcca tcctggctca ctcttagtaa cttttgcccg
    16921 cgaatgatga ggagattaag aatgctgaag aatctggcta aactggatca aacagaaatg
    16981 gataaagtga atgtcgattt ggcggcggcc ggggtggcat ttaaagaacg ctacaatatg
    17041 ccggtgatcg ctgaagcggt tgaacgtgaa cagcctgaac atttgcgcag ctggtttcgc
    17101 gagcggctta ttgcccaccg tttggcttcg gtcaatctgt cacgtttacc ttacgagccc
    17161 aaacttaaat aaaacttata cagagttaca ctttcttaca taacgcctgc taaattatga
    17221 gtattttcta aaccgcaccc ataatttgca gtcattttga aaaggaagtc attatgtcgt
    17281 tctggaaagt tgcagcagcg caatatgagc ctcgtaaaac ctcactcacc gaacaggtag
    17341 ctcatcatct ggagtttgtg agggccgccg ccaggcaaca atgtcagctg ttagtttttc
    17401 catcgctttc tttactgggg tgtgattatt cgcgacgtgc ccttcctgcc ccacccgatc
    17461 tctcactgtt agacccgctt tgttatgccg caacgacctg gcgaatgacc atcattgccg
    17521 gccttcccgt tgaatataac gatcgcttta ttcgtggaat tgcggtgttc gcaccgtggc
    17581 gaaaaacgcc tgggatctac catcagagtc atggtgcatg tctgggtcgt cgttccagaa
    17641 ccatcacggt ggtcgatgaa caaccggaag gtatggatat ggacccgacc tgttcactgt
    17701 ttactacagg gcaatgtctg ggagaacccg acctgctggc gtcggcccgt cgcttacaat
    17761 ttttttcaca tcagtactcg attgccgtgc tgatggcaaa tgcccgtggt aacagtgcac
    17821 tatgggatga atatggtcgt ctcatcgttc gcgccgatcg tggttcatta ttgttagtcg
    17881 gtcagcgttc atcacagggt tggcaaggcg atatcattcc attacgctag gctttttcgg
    17941 cctggagcat gccatgttgc gcattatcga tacagaaacc tgcggtttgc agggagggat
    18001 cgttgagatt gcctctgttg atgtcattga cggaaaaatc gtcaacccca tgagccacct
    18061 ggtgcgcccc gatcgtccta ttagtccaca agcgatggcg attcatcgca tcaccgaagc
    18121 catggtcgcc gataaaccgt ggattgaaga tgtgatccca cactattacg gtagtgaatg
    18181 gtatgtcgcg cataacgcca gctttgaccg ccgcgtactg cctgagatgc ccggtgagtg
    18241 gatttgcact atgaaactgg cccgtcgttt gtggcctggg atcaagtaca gcaatatggc
    18301 gttatataaa acacgcaagc tcaatgtaca gacgccgccg ggcctgcatc atcaccgcgc
    18361 gttgtatgac tgttatatca ccgccgcgtt gcttatcgat attatgaaca cctccggctg
    18421 gacggcagaa cagatggccg atatcaccgg acgtccgtcg ttgatgacga ccttcacctt
    18481 tggcaaatac cgtggcaaag cggtttccga cgttgccgaa cgcgatccgg gctatctgcg
    18541 ctggttattt aataacctgg acagcatgag cccggagctg cgtttaacac tgaaacatta
    18601 tctggaaaat acttagtccg caggcgtagc gggtaatgtt ccctgcgcca gcgcgaccag
    18661 aaaagcatat tccatcgcta cgccttcgta cgatttaaag cgaccagatt taccgccatg
    18721 gcctgagtcc atgtcggtac agagcaataa aagatggtca tcggttttca gctcgcgcaa
    18781 tttagcgacc cattttgccg gttcccaata ttgcacctga gaatcgtgca aaccggtcgt
    18841 taccagtaaa tgcggataag cctgtgcggt gacgttgtca tatgggctgt agcttttcat
    18901 gtactcgtaa tattgcggat cctgcggatt cccccactct tcaaactcac cagtggtaag
    18961 aggaattgat tcatcaagca tcgttgttac aacatcaaca aacggtacct gggcgataac
    19021 gccgtggaat aattccgggc gttgattaat tgcaacgccc atcaacatgc cccccgcact
    19081 cccgcccatc gcataacaaa gcgaaggaga gccatagccc agttttaaca atgcatcgca
    19141 ggcatcaaga taatcattaa acgtattttt ctttttcaga aattttccgt cttcgtacca
    19201 ttgttgcccc agctcaccac cgccgcgaac atggacaatg gcgtagacaa agccacgatc
    19261 taacaaactc aagcggctaa aactgaaatc ggcatcaata cttgcgccgt aagaaccata
    19321 gccatacacc agcaacgggt tgtgtccttt gcgaaaatgt ttgcgatggt agaccaacga
    19381 aaccggaact tcgacgccat cacgggcgac tatccacagg tgttcactgc ggtaattcgc
    19441 cgcatcaaaa ccaggaactt ccgtttgttt taatacacga cgctcaccgg tatccatatc
    19501 cagttcaaac aaagtatctg gtgtggtcat ggaagaataa ccataacgca atcgcgcggt
    19561 ttcaggttct ggattgtagg caatccaggt cacataggcc ggatcatcaa aggcaatacc
    19621 aatgacttcc cgggtcttgc ggttaatttg gcgcaaactg gttaacccgc gctgacgctc
    19681 ttcaaccacc agccagtcgg taaacagcgt aaacccttcc agcataatgt tatcgcgtgg
    19741 cggaattaac tcttcccact gttgctcatc acgcaggcgg gtacggtata agccaaagtt
    19801 tttgccatgg cggttggaac gcagataaaa ccgatgctgg tagtgatcaa ggctgtattc
    19861 gtgatctttg cggcgcggca gaaaaacaaa cggctcggca tcggccattt ccgcgtccag
    19921 caggcgaact tcactggtgg tggcgctggc caaatgaatg actacatagt gcttcgaggt
    19981 cgttttatgc aggctgacgt aataggtatc gtctttttct tcgtagatca gtttatcttg
    20041 cgatgctggc gtaccgatgg cgtgacgcca gacctgataa ggcagcagcg tcaccggatg
    20101 cttgcgaaca tagtagaaag tccaggagtc atttgcccag acaaagctgg gttcaacgtt
    20161 atccagcagt tccgggtacc agttaccagt ttccagatta cgaaaacgaa tgccgtactg
    20221 gcgtcgggaa agaaaatctt ctgccagcgc cataatggtg ttatcgggcg taatcgccat
    20281 tccgcccatc gaataaaact cactatgagc tgcgcgctta ttggcatcga gcaatgtttc
    20341 ccactcatcc cactcttcac tgaatgccga ttgacgctgg tagatagcat attcacagcc
    20401 tggttcataa atatgccgat agcggtagcc atttttgatg tagggcgcag aaacttctcg
    20461 ttgcggaatg cggtcgatga tttcctttaa gatgcgatcc tgcaaggctt gttgtgaggc
    20521 catcacccga tgaccgtaac tattttcttg ttgcaggtag tccaggactt ctggctgaga
    20581 acgcgtatcg tcccgcagcc agtagtaatt atcgatgcgc gtatcgccat gaagcgtcat
    20641 ggcgtgggga atgcgggcgg cttttggtag catgttattg ttctttctgg ttgaaacatc
    20701 ttataagggt ggcaaaactc accggggatg caagcgaaac aggggagtca ttgcttagat
    20761 gatgacaggt aatggcgcgg atatcgaatg ttatgcagac agagaaaatc agcctgttca
    20821 aatggctgtg cgattctgga tagcccgaaa tagtcaactt caggctatcc agagagcgga
    20881 attattccgc caaagtgcgt ttttgctgtt cgagatcgcg ttcaatgccg tcacgaacat
    20941 cctgggggat tttcagcgcg tcacccagtg cattcaggta actgcgttcc ataaaatggt
    21001 caatatcaat agccgcgcaa ctcaggaaat agatttccag cgcctcttct tcattgcgga
    21061 ccccggtagc caggcgttgt ggatccagcg gttgttcgat tgcctgctca atgagtacac
    21121 gcccctgctc ttccacgccg gcttcacgca attgctggtc gattgccgca cgttctttgg
    21181 catcaatatg accatcactt ttagcggcaa agaccagcgc aaggatcaaa cgttctgtac
    21241 gctcatccag cggcgtactt tgcgcgccaa actgcggttc gtcctgatgc gccgcgcgaa
    21301 ttttatcttt gtatttattc cacagcaccg tacccgctac cgctccgccg ccaaccagta
    21361 acgcgttggt gccatatttc gtaagaagtt tacgtgctga tttatttgcg accagcagcc
    21421 cagccagtcc gcctaatgcg cctggcacta acagtttgcc caatccctga tccgcagacg
    21481 aggaggtaga agaactgctt tgcccaagca gggattgcag ttgatttaac cagttagcca
    21541 tatttgctcc tcaataacca tttttagtgc ctgtagcata gcggatgagg atgtcagaaa
    21601 atgtatatcg agacaaaaga tgcgcaaata agcggggcgg taggccgtta ttcaaagaaa
    21661 ttcgcgccag gtaaggtatt tactgtatat caggtgataa gggtatttta ggtgaaagta
    21721 gtttgtcgtt ttgagtggca ttgtttgatg ctgattgccc gatgcgacgc tgttgcgtct
    21781 tctcaggcct acgattgtgg tgcgttctgg ggcggacaag gcactcgcgc cgcatccgcc
    21841 aacggtcaat cgaattatca gaagccatta acgccgctga tattccgcca ttcccgcttt
    21901 gcagtccacg ctgacctggt aatgaatatc ggcactttta ccacgcacgg ttagcggtac
    21961 tgaccattta tcatctttac cctgaatgtc ctgcaaactg acccaagcca cgggatcggc
    22021 ctgaccgaca attttttgat catctgccca gcgcgccacg cgattttgtt gataatcacg
    22081 ttttacgctc gcggcaattc cggcagcatc cagaccttca cactttggga aagtgaccga
    22141 cttgctggtt tcattattgg cagcgaaaac tgatgcgcag gcagaaacca acaacagccc
    22201 taaaaacgcc cctctttttt tcatgttttt ctccatagca caatgattca ggagaaagca
    22261 tggtacaaat tgtcaggagc gcaagttgct tcaggccgcg tgtgaggcat cttcctcttc
    22321 ggattcagca ccgacgacct gtggggacgg taatttgccg gttttcagaa tggtgctcag
    22381 cacatctttt tgttctgcca gccatagcga aagggcttca cgttgctcgt cttccatttg
    22441 cactggagaa tttgtcagcc aggtgtcaag cagatccgcc gtatcaagca ttttatcata
    22501 agcatcggct tcctttttgc tggtaaacga cattttctct tcgccctcac gaatgactac
    22561 gtatttaact tcaaccgcca tttgcagcct ctcataataa ctgtgatttt atacagtgta
    22621 tttcttttcg gttgagaaat caacatcagc aataaagaca cacgcaaacg ttttcgttta
    22681 tactgcgcgc ggaattaatc aggggatatt cgttatgacg ttattaggca ctgcgctgcg
    22741 tccggcagca actcgcgtga tgttattagg ctccggtgaa ctgggtaaag aagtggcaat
    22801 cgagtgtcag cgtctcggcg tagaggtgat tgccgtcgat cgctatgccg acgcaccagc
    22861 catgcatgtc gcgcatcgct cccatgtcat taatatgctt gatggtgatg cattacgccg
    22921 tgtggttgaa ctggaaaaac cacattatat cgtgccggag atcgaagcta ttgccaccga
    22981 tatgctgatc caacttgaag aggaaggact gaatgttgtc ccctgcgctc gcgcaacgaa
    23041 attaacgatg aatcgcgagg gtatccgtcg cctggcggca gaagagctgc agctgcccac
    23101 ttccacttat cgttttgccg atagcgaaag ccttttccgc gaggcggttg ccgccattgg
    23161 ctatccctgc attgtaaaac cggtgatgag ctcttccggc aaggggcaga cgtttattcg
    23221 ttctgcagag caacttgctc aggcatggga atacgctcag caaggcggtc gcgccggagc
    23281 gggccgcgta attgttgaag gcgtcgttaa gtttgacttc gaaattaccc tgctaaccgt
    23341 cagcgcggtg gatggcgtcc atttctgtgc accagtaggt catcgccagg aagatggcga
    23401 ctaccgtgaa tcctggcaac cacagcaaat gagcccgctt gcccttgaac gtgcgcagga
    23461 gattgcccgt aaagtggtgc tggcactggg cggttatggt ctgtttggtg tcgagctgtt
    23521 tgtctgtggt gatgaggtga ttttcagtga ggtctcccct cgtccacatg ataccgggat
    23581 ggtgacgtta atttctcaag atctctcaga gtttgccctg catgtacgtg ccttcctcgg
    23641 acttcctgtt ggcgggatcc gtcagtatgg tcctgcagct tctgccgtta ttctgccaca
    23701 actgaccagt cagaatgtca cgtttgataa tgtgcagaat gccgtaggcg cagatttgca
    23761 gattcgttta tttggtaagc cggaaattga tggcagccgt cgtctgggtg ttgcgctggc
    23821 gaccgctgag agtgttgttg acgccattga acgcgcgaag cacgccgccg gacaggtaaa
    23881 agtacagggt taaacccggc aaaaaaacgc tacaaaaatg cccgatcgta gatcgggcgt
    23941 tttgactttt acagcttagc gccttctaca gcttcacgcg ccagcttagt aatgcggtcg
    24001 taatcgcccg cttccagcgc atctgccgga accagccagg aaccaccgat gcacagcacg
    24061 cttttcagcg ccaggtagtc acggtagtta gccggagaaa taccacccgt cgggcagaaa
    24121 cggacctggg agaacggacc cgcgatcgcc tgcagggctt tcacgccgcc gttagcttca
    24181 gccgggaaga atttgaactc tttcaaaccg tagtccatac ccagcatcag ttcggaaaca
    24241 gtgctgatcc ccggaattag aggaatagtc ccttcggtag cagctttcag cagcggctcg
    24301 gtcagacccg ggctaattgc gaactgtgca cccgcttcag tgacttctgc cagctgctgt
    24361 ggattcagca ccgtaccggc acccacaatc gcttcaggca cttctttggc gatagcacgg
    24421 atagcgtcaa ctgcacactc ggtacgcaga gtcacttcca gaacgcgcac cccaccagca
    24481 accaacgctt ttgccatcgg cactgcgtgt tccagttttt ttaccacgat aaccggtaca
    24541 accgggccgg tggtcaggat tgattctgca cttgttttcc agtttttcat cagagttttc
    24601 tctcgcctga ttacaaattt gtcgtcttaa aaagtgatac aggttgcgcc ctgttcggca
    24661 ccggacagtt tttcacgtaa ggcgctgaat aattcacgtc ctgtccccac gcgtgacgcg
    24721 ctcaggtcag gaatgtgcgg ttcgcgagca gccagttccg cttcgtctac cagcagcgtc
    24781 agttcgcctg tctgtccatt cacacgaatg atgtccccgt cgcgcacttt tgccagcagc
    24841 ccgccatcgt aggcttctgg tgttacgtgg atagctgacg gcactttacc tgaagcgccg
    24901 gagagtcgtc catcggtaac taacgcaatt ttgaaacacc ggtccaataa tacaccaagt
    24961 ggcggcatga gtttatgtaa ttctggcatt ccgttcgctt ttggcccctg atgacggaca
    25021 acaacgacac aatcgcggtc cagcaaaccc gcttcaaagg ccggcataac gtcatgctgg
    25081 ctttcaaaaa caaccgctgg cgcttcaatc acctggttct caaccggcac ggcagaggtt
    25141 ttcataaccg cacggcccag gttaccgctt aacacttttg tcccaccatg atgagagaaa
    25201 ggttgttcga aggaagcgat cacattgctg tcgagtgatt tttccgcccc ttcccgccag
    25261 tccagttcac cattattcag ccatggttca agggtataac gagacagacc aaagcctgcc
    25321 accgtattga catcttcatg cagcaggcct gctttgagca gttcacgcac cagaaccggt
    25381 acgccacctg ccgcctggaa gtggttaata tcggccggac cgttcgggta gagacgtgcc
    25441 atcagcggta caacatcaga aaggtcggag aagtcatccc agttaatctg aataccggcc
    25501 gcgcgcgcca tcgccaccag gtgcatggtg tggttagtgg aaccaccggt cgccagcaga
    25561 gcaacaatac cgttcaccac cactttctca tcgatcatct taccgatcgg catccattca
    25621 ttgccattac cggtcatgcg tgtaacctga cgcgcagcgg cagcggtcaa agcatcgcgc
    25681 agcggagaat ccggatgaac aaaagaagag cctggcaact gcatccccat aaattccacc
    25741 accatctggt tggtgttggc agtaccgtag aaagtacatg ttcccggcgc atggtaagac
    25801 gcggcttctg actccagtaa ggccatgcgg tccactttac cttcggcata aagctggcga
    25861 atacgcactt tttctttatt tggcaaaccg cttgccatcg gtccagacgg cacaaacacc
    25921 gcaggcaaat gaccaaacga cagggctgcc atcgtcagac ccgggacaat cttgtcgcac
    25981 acaccgagga acagagcacc atcaaacatg ttatgggaca gcccgaccgc cgcagacatc
    26041 gctatcactt cgcggcttag cagcgacaat tccattccat cctgcccctg ggtgacacca
    26101 tcacacatcg ccggaacacc gcccgcaacc tgaccaaccg cattcgcttc atgcagggct
    26161 ttacgaatga tttctggata gtgttcataa ggctggtgcg cggagagcat gtcgttatag
    26221 gaggtgatga tggcgatatt gttacgcaac atgcttttca aagaggcttt gtcttctggc
    26281 tggcaggcag cgaaaccgtg tgccaggtta ccgcatgcca actgcgaacg atgaacggtc
    26341 gaagttttcg cttgttctat ccgggcgaga taagcagagc gagtctcgcg cgaacgttca
    26401 atgattcgat ttgttacgcg taacaattgt ggattcataa aggctcctga aattgagttg
    26461 tcagagcagg atgattcaca acgcgtttca ttcagaggat ttatgactga aacgcctgta
    26521 accggagctc atagggcaaa aacgtttcag tcagtgtaat aaaaaaagcc tcgtgggtga
    26581 atccgcacga ggcctgaaag tgtaaaaatt gttctacaat ctgtgcaaga tcatgttacc
    26641 ggtaaaataa ccataaagga taagcgcaga tattactcaa actcattcca ggaacgacca
    26701 tcacgggtaa tcatcgccac cgaggcaacg ggtccccagg ttccggcctg atacggtttc
    26761 ggcgcatcat tgtccatcgc ccacgcctca gtaatggagt ctacccattt ccaggcttct
    26821 tccacttcgt cgcgacgaac aaacagtgcc tgaataccac gcatggtttc cagcagcaaa
    26881 cgttcatagg catccgccag atgcgtctga ttaaaggttt ctgaatagct cagatccagc
    26941 ttggtgattt gcaggttatg tttgtggtca aggccaggaa ctttattcag tacctggata
    27001 tccacgcctt catcaggttg cagacggata gtcagtttat tctgcggcag atcctgccac
    27061 gattctttaa acagattcag ttcaggtgtt ttgaaataga ccacgacttc agaacatttg
    27121 gtcggcagac gtttaccagt acgcaggtag aatggcacac cggcccagcg ccagttatca
    27181 atgtcgacgc ggatcgctac gaaggtttct gtattgctgc tcttgttcgc gccctcttct
    27241 tccagatatc ccggcacttt tttgccctgg gcgaagcccg cagtatattg cccgcgtacg
    27301 gttttttcgc gtacgttgga gcggtcgatg cggcgcagag acttcagtac tttcactttt
    27361 tcatcgcgga tgctgtctgc gctcaggtca gacggcggag acatcgcaat catgcagaga
    27421 atttgcagca ggtggttttg gatcatatcg cgcatctgac cggctttatc aaaatagccc
    27481 cagcgccctt cgatccccac ttcttctgcc acggtaatct caacatgatc aatggtgcga
    27541 ttgtcccagt tattcacaaa cagggagtta gcaaaacgca gcgccaacag gttcagcacc
    27601 gtttctttac caagatagtg gtcgatacgg taaacctggc actcctcgaa gtattcgcca
    27661 acctgatcat tgatttcctg cgaggtcgcc agcgacgtcc ccagcggttt ctccataact
    27721 acgcgtgccg gtttagcatt cagttttgcc tcaccaagcc ctttgcaaat tgcgccaaaa
    27781 gtgctgggcg gcatggcaaa gtagttaatg gtgatacgat ttttttgatc cagcatcgcg
    27841 ccgagacggc tgaatgcagc agtgtcattg acatcgagat tacaaaaatc cagacgtgca
    27901 ctcagggtgt cccataaacc ttcatcaata gtttctttca tgaaagtttc gagcgcctca
    27961 cggacaactt tggtataagc cgctttatcc cagtcagcac gccctacgcc gataatccgg
    28021 gtgtccgggt tgagctgacc ggctttttcc agttgataca gggaaggcag caatttacga
    28081 cgcgcaaggt cgcctttcgc gccgaaaatg accaggtcac aggcctgggc tgtttgcgtt
    28141 accgccatgt cattctcctt aagttaacta acccggtact taagccaggg tatacttgta
    28201 attttcttac ggtgcactgt actgctttta cgagcttgcg aaaactgtaa acgcttatcc
    28261 acccgtgcga ttacgggaaa agcgcgcaaa gtgcggcaaa actgataaaa aaatcatcgt
    28321 tttccattcg gtaaaaatct gacactgatc atgttatgaa aaaaaataac aactttttta
    28381 tctgcttttg tcattaacac ggcacacagg cgtaatatct gacaaaactg catttcgatt
    28441 tctttcagtg cggaaatcgt cattacccgt gagtctcttt acatcatgaa tatgctggaa
    28501 aaaatccagt ctcagctgga acatttgagc aaatcagagc gcaaagttgc cgaggtcatt
    28561 ctggcttcgc ccgataacgc gatccattcg agtattgctg ctatggcact ggaagccaat
    28621 gttagcgaac cgacggtgaa tcgtttctgt cgcagcatgg acacgcgcgg ttttcctgat
    28681 tttaaacttc atctggcaca gagtctggcg aatggcactc cctatgttaa tcgcaacgtc
    28741 aatgaagatg acagcgttga atcatacaca gggaaaatat ttgagtccgc aatggcaacg
    28801 ctcgatcatg tccgtcattc actggataaa tctgccatca accgcgccgt cgacttgctc
    28861 actcaggcaa aaaaaatcgc ctttttcgga ttaggctctt cagccgccgt tgcccacgat
    28921 gcgatgaata agttctttcg ttttaatgtt ccggtggtgt actccgatga tattgtgctg
    28981 caacgcatga gttgtatgaa ttgtagcgac ggagacgtgg tggtgctgat ttctcacact
    29041 ggaagaacaa aaaatctggt cgagctggcg cagctggctc gcgaaaacga cgcaatggtg
    29101 attgccctca cctctgcggg taccccgctc gcccgggaag caacgctggc aattaccctc
    29161 gacgtaccgg aagatactga catttatatg cccatggttt ctcgacttgc acagctgacc
    29221 gtgatagatg tgctggcgac aggatttact ttgcgacgcg gtgcaaaatt cagagataac
    29281 ttgaagcggg tcaaggaagc gctgaaggaa tcgcgttttg ataagcagtt acttaattta
    29341 agtgacgatc gctaaaaacg actgtcactg tcctaatctt atacgacatc cgaatgagat
    29401 taatttatcg ccatcgcggc gttatttcat tcggatttca tgttcaagca acacctggtt
    29461 gtttcagtca acggagtatt acatgtccag aaggcttcgc agaacaaaaa tcgttaccac
    29521 gttaggccca gcaacagatc gcgataataa tcttgaaaaa gttatcgcgg cgggtgccaa
    29581 cgttgtacgt atgaactttt ctcacggctc gcctgaagat cacaaaatgc gcgcggataa
    29641 agttcgtgag attgccgcaa aactggggcg tcatgtggct attctgggtg acctccaggg
    29701 gcccaaaatc cgtgtatcca cctttaaaga aggcaaagtt ttcctcaata ttggggataa
    29761 attcctgctc gacgccaacc tgggtaaagg tgaaggcgac aaagaaaaag tcggtatcga
    29821 ctacaaaggc ctgcctgctg acgtcgtgcc tggtgacatc ctgctgctgg acgatggtcg
    29881 cgtccagtta aaagtactgg aagttcaggg catgaaagtg ttcaccgaag tcaccgtcgg
    29941 tggtcccctc tccaacaata aaggtatcaa caaacttggc ggcggtttgt cggctgaagc
    30001 gctgaccgaa aaagacaaag cagacattaa gactgcggcg ttgattggcg tagattacct
    30061 ggctgtctcc ttcccacgct gtggcgaaga tctgaactat gcccgtcggc tggcacgcga
    30121 tgcaggatgt gatgcgaaaa ttgttgccaa ggttgaacgt gcggaagccg tttgcagcca
    30181 ggatgcaatg gatgacatca tcctcgcctc tgacgtggta atggttgcac gtggcgacct
    30241 cggtgtggaa attggcgacc cggaactggt cggcattcag aaagcgttaa tccgtcgtgc
    30301 gcgtcagcta aaccgagcgg taatcacggc gacccagatg atggagtcaa tgattactaa
    30361 cccgatgccg acgcgtgcag aagtcatgga cgtagcaaac gccgttctgg atggtactga
    30421 cgctgtgatg ctgtctgcag aaactgccgc tgggcagtat ccgtcagaaa ctgttgcagc
    30481 catggcgcgc gtttgcctgg gtgcggaaaa aatcccgagc atcaacgttt ctaaacaccg
    30541 tctggacgtt cagttcgaca atgtggaaga agctattgcc atgtcagcaa tgtacgcagc
    30601 taaccacctg aaaggcgtta cggcgatcat taccatgacc gaatcgggtc gtaccgcgct
    30661 gatgacctcc cgtatcagct ctggtctacc aattttcgcc atgtcgcgcc atgaacgtac
    30721 gctgaacctg actgctctct atcgtggcgt tacgccggtg cactttgata gcgctaatga
    30781 cggcgtagca gctgccagcg aagcggttaa tctgctgcgc gataaaggtt acttgatgtc
    30841 tggtgacctg gtgattgtca cccagggcga cgtgatgagt accgtgggtt ctactaatac
    30901 cacgcgtatt ttaacggtag agtaagtacg ttgccggatg cggcgaaaac gccacatccg
    30961 gcctacagtt caatgatagt tcaacagatt tcgaatattc tgaagcaaac ttgaacttat
    31021 catcaggcga aggcctctcc tcgcgagagg cttttttatt tgatgggata aagatctttg
    31081 cgcttatacg gctggatttc gcccggtttg cgagttttca gcaattttag tatccaggtg
    31141 tattgttctg gtcgcggacc aacaaaaatc tcgacttctt cattcatccg ccgcgcaatc
    31201 gtatgatcat ccgcctctaa cagatcatcc atcggtgggc gcacctgaat cgtcagacgg
    31261 tgcgtcttgc catcataaat cggaaacagc ggaacaacgc gcgcacggca cactttcatc
    31321 aaacgaccaa tcgcgggcaa cgtcgcttta taggtggcaa agaaatcaac aaattcgctg
    31381 tgctcagggc catgatcctg atcgggtaaa taatatcccc agtagccctg acgtaccgac
    31441 tggatgaatg gtttaatacc atcatttctc gcatgcagac gaccgccaaa acgacgacgc
    31501 accgtgttcc agacataatc aaaaaccggg ttgccctgat tatggaacat cgctgccatt
    31561 ttctgccctt gcgaggccat cagcatggca ggaatatcga cggcccaacc gtgcggcacc
    31621 agaaagataa ctttctcgtt attacgccgc atctcttcaa tgatctccag cccttgccag
    31681 tcaacgcgcg gctgaatttt ctccggcccg cgtattgcca actcagccat cattgccatc
    31741 gcttgcggcg cggtggcaaa catctcatca acaatcgctt cgcgttcagc ttcactacgt
    31801 tctggaaagc agagcgacag attgattaac gcacgacggc gtgagctttt tcccagtcgt
    31861 ccggcaaaac gtcccagccg tgccagaatg ggatcacgga actttggcgg cgttaaagcg
    31921 atacccgcca tcgctgctac gcccagccat gctccccagt agcgcgggtg gcgaaaggat
    31981 ttatcaaact caggaatgta ttcgctatta ttttttttcg tttccatgct tttccagttt
    32041 cggataaggc aaaaatcaat ctggtgatag tgtagcggcg caacttgccc cgcaccaaat
    32101 aaaaaaagcc ggtactgact gcgtaccggc tgcgaatgga tgttaattaa tcaaaccgta
    32161 gctgcggcac aatctctttg gcctgcgcca ggaattcgcg acgatcggag ccggtcagcc
    32221 cttcggtacg cggcagtttt gccgtcagcg ggtttacggc ctgctggttt atccatactt
    32281 catagtgcag atgtggcccg gttgaacgtc cggtattacc ggaaagcgcg atacggtcgc
    32341 cacgtttcac cttctgtccc ggtttcacca gaatcttgcg caagtgcata taacgcgtgg
    32401 tgtagctgcg accatgacga atagccacat aataacctgc tgcgccactg cgtttggcaa
    32461 ccaccacttc accgtcaccc actgaaagca ctggcgtacc ctgcggcatg gcgaaatcaa
    32521 cacctctgtg tggtgcaacg cgaccggtca caggattagt acgacgcggg ttaaagttag
    32581 acgagatacg gaactgtttc gccgtcggga atcgcaagaa tcctttcgcc agaccagtac
    32641 cgttacgatc gtagaatttg ccatcttcag cgcggatagc gtaataatct ttaccttctg
    32701 aacgcaaacg tacgcccagc agctggcttt gctcacgttt accatcaagc atttctcgag
    32761 acattaatac cgcaaattca tcgccttttt tcagtttgcg gaaatccatt tgccactgca
    32821 tggctttaat cactgcgctc acttcggcgc tggttaaacc ggcgtttctg gcgctggcaa
    32881 caaagctccc cccgacggta cctttcagca gattgttaac ccactctcct tgctgcattt
    32941 cgctggtcat tttaaaaccg ttagcggcag tacggtcata ggttcgggtt tcacgacgag
    33001 acacttccca ggtgaggcgc tgcagttcgc cgtccgcggt taatgtccag gagagttgtt
    33061 gaccgatttt caggttacgc aattctttgt cggcagcagc cagttgggtg atatcaccca
    33121 tatcaatacc atactgattg agaatgctgc ttagcgtatc gccagtggaa acaacatatt
    33181 catgcacgcc cgcttcaccg gcgattttgt catccagttc gtcctgggga atggcttcat
    33241 cttcttgtgc agcttgatca atcggctcac tggcttcagg taagagcgaa cgaatttcgt
    33301 tctgttccag ctcaatggtt ttgacaattg gcgtggcatc gcggtgataa acatagggcc
    33361 gccagacagc gacggccaga gtaagaacgg tgagcgaccc caacataacg cggtgtggtc
    33421 gcggtaaatt attaaacgcc agggcgacag agcgggctat ctgttgcacg taatcacttc
    33481 ctcattaatc tcctttcagg cagctcgcat actggttggc taattgactc aggaattctg
    33541 aatagcttgt tttacccagt ttgatattcg tccccagggg atccaacgtt cccatacgaa
    33601 cggatgtccc tcgtgcgacg ctctcaacga ccgctggcct gaactgtggc tcagcaaaaa
    33661 cgcaggttgc tttttgctca accaactgtg ttcttatttc atgtaaacgc tgcgcgccag
    33721 gttgaatctc agggttaacg gtaaaatgac caagcggtgt cagtccaaac tgtttttcga
    33781 aatagccgta agcatcgtga aaaacgaaat aacctttccc cttgagcggc gcgagctcgt
    33841 taccaacctg cgtttcggtt gaggctaatt gtgcctcaaa atccttcagg ttggcgtcaa
    33901 gtttggctcg actttgcggc ataagttcca ctaattttcc atggattgca accgctgtag
    33961 cccgcgctat ctctggggaa agccaaagat gcatgttgaa atcgccgtga tggtgatctt
    34021 cgtcactttt ttccgcgtgg tcgtgatcat catcatcgcc gtgaatactt ttcatcagta
    34081 gcggtttcac atcttcaagc tgcgcaatcg ttacctgctt cgcttctggt aatttgctta
    34141 ccggtttttg cataaacgct tccatctccg ggccaaccca aacgactaag tccgcgttct
    34201 gtaagcgttt tacatccgat ggacgcagtg aataatcatg ttctgaagcg ccgtcaggca
    34261 gtaaaacctc cgtttctgtt acaccatcag caatggcaga agcgatgaac ccaacgggtt
    34321 taagcgaagc gacaacggcg gcatctgcgg cctgtgttgc acctccccag agagcggcgg
    34381 ataatgctgc gaaaagaagc gtttttttat gtaacataat gcgaccaatc atcgtaatga
    34441 atatgagaag tgtgatatta taacatttca tgactactgc aagactaaaa ttaacatgac
    34501 aagtctggtt tccctggaaa atgtctcggt ttcttttggc caacgccgcg tcctctctga
    34561 tgtgtcgctg gaacttaaac ctggaaaaat tttgacttta cttgggccaa atggcgcagg
    34621 taagtcgaca ctggtacggg tagtgctcgg gctggtaaca cccgatgaag gggttatcaa
    34681 gcgcaacgga aaactgcgca tcggctatgt accgcagaag ctgtatctcg acaccacgtt
    34741 gccactgacc gtaaaccgtt ttttacgctt acgccctggt acacataaag aagatatttt
    34801 gcctgcactg aaacgtgtcc aggccgggca cctgattaac gcaccgatgc aaaagctctc
    34861 tggtggcgaa acgcagcgtg tactattagc gcgagcattg ttaaatcgcc cgcaattatt
    34921 agtgctggat gaacccactc aaggcgtgga tgtaaatggc caggtggcgt tatatgacct
    34981 tattgaccaa ctgcgtcgcg aactggattg tggcgtttta atggtctctc acgatctgca
    35041 tctggtaatg gcaaaaaccg atgaagtgct gtgtctgaat caccacattt gttgttccgg
    35101 cacaccggaa gttgtttccc tacatccgga gtttatttct atgtttggtc ctcgtggtgc
    35161 tgaacaactg ggtatctatc gccatcatca taatcatcgt cacgatttac agggacgaat
    35221 tgttttgcgt cggggaaatg atcgctcatg attgaattat tatttcccgg ttggttagcc
    35281 gggatcatgc tcgcctgtgc cgcgggtccg ctgggttcgt ttgtagtctg gcgtcgtatg
    35341 tcttatttcg gtgatacgct ggctcatgcc tcattacttg gcgtcgcgtt tggtttgttg
    35401 ctggacgtga atccattcta tgcggtaatt gccgttacgc tgctcctggc gggcggtctg
    35461 gtatggctgg agaagcgtcc acagctggcg attgacacgt tattagggat tatggcgcac
    35521 agtgccctgt cgctgggcct ggtggtcgtt agtctgatgt ctaacattcg tgttgatttg
    35581 atggcttacc tgttcggtga tttgctggca gtgacgccag aagatctcat cgctattgcg
    35641 attggcgtgg tcatcgtggt ggctattttg ttctggcaat ggcgcaattt gctgtcgatg
    35701 acgattagcc cggatctggc gtttgttgat ggtgtgaaat tacagcgcgt gaaattgttg
    35761 ttgatgctgg tgacggcatt gacgattggt gtagcgatga aatttgttgg cgcgttgatt
    35821 attacttcac tgctgattat tcctgcagct actgcgcgtc gctttgcccg tacgccggaa
    35881 cagatggctg gtgtcgctgt tttggtgggg atggtggcag taactggcgg tttaaccttt
    35941 tccgcgtttt acgatacgcc ggcgggtccg tcggtggtgc tatgtgcggc actgttattt
    36001 attctcagta tgatgaaaaa gcaggccagc taatctatcg ctgaacacat ttgtcggatg
    36061 cggcgcgagc gccttatccg acctacggtt cgctatctct ggctggcctg ataagacgcg
    36121 aacagtgtcg catcagacac actgccagtg tcggatgcgg cgcgagcgac caatccgact
    36181 tacggcattt ctggcggcgt tatgccaaag tgattccacg cccgcgtcgt cgccatacgc
    36241 ccacgcggtg tacgctgcaa aaagccttgc tgaatcaaat aaggttccag cacatcctca
    36301 atggtttcac gttcttcgcc aatggctgcc gcaaggttat ccagacctac cggcccacca
    36361 aagaacttat cgattaccgc cagcaataac ttgcggtcca tataatcgaa accttcagca
    36421 tcgacattca acatatccaa cgcctgagca gcgatatctg ccgagatggt gccatcgtgc
    36481 ttcacttcgg cgaaatcacg cactcgacgc agcagacggt tggcaatgcg cggcgtaccg
    36541 cgagctcgac gagcaacttc cagcgcgccg tcatcactca tctcaagccc cataaagcgt
    36601 gcgctgcgac tgacgatata ttgcagatcc ggcacctgat aaaactccag acgctgcaca
    36661 ataccaaaac gatcgcgcaa cggtgatgtc agcgaacctg cgcgcgtggt tgcaccaatc
    36721 agggtaaacg gcggcaaatc aattttaatg gagcgtgccg ccggaccttc accaatcatg
    36781 atatccagtt ggtagtcttc cattgccgga tacaacacct cttccaccac tggcgaaaga
    36841 cggtggatct catcaataaa caacacgtca tgcggttcaa ggttagtgag catcgctgcc
    36901 agatcgcccg ccttttccag caccggacca gaagtcgtgc gtaaattaac gcccatttca
    36961 ttggcgacga tgttggcaag cgtagtttta cccaaccccg gaggaccgaa aatcaacaga
    37021 tgatcgaggg catcgccgcg cagtttcgct gctttgatga aaatctccat ctgtgaacga
    37081 acctgcggct gaccaacata ctcttccagt aatttagggc gaatggcgcg atctgccaca
    37141 tcttccggca aagtggtacc ggcagaaatc agacggtctg cttcaatcat cctttacctc
    37201 ataacgcggc gcgtagggct tcgcgaatta atgtttcact gctggcgtca gggcgagcga
    37261 ttttgctcac catgcggctt gcctcttgtg gtttatagcc cagcgccacc agcgcggcaa
    37321 ctgcttcttg ttcagcatcg tcggtcgccg ggctggcagg tgatgtgagt accaggtcgg
    37381 cggctggcgt aaagagatcg ccatgcaaac ctttaaatcg gtctttcatt tcaacaatca
    37441 agcgttcggc ggtttttttg ccaatacccg gcagtttcac cagcgccccc acttcttcac
    37501 gctcaacggc attaacgaac tgctgcgctg acattccgga gaggatcgcc agcgccaact
    37561 tcgggccgac gccgttggtt ttgatcaact ctttgaacaa tgtgcgctct tgtttattgt
    37621 taaaaccgta cagcagttgc gcgtcttcac gcaccacaaa gtgggtgaaa acgatcgctt
    37681 cctgacccgc ttcagggagt tcataaaaac aggtcatcgg catatgcact tcatagccta
    37741 cgccgcccac ttcaattaac accagcgggg gttgtttttc aatgatgatg cctctgagtc
    37801 tgcctatcac atgacgctcc tgcgtaatga atcaaagata atgctgtatg ataaaaaaat
    37861 gctggataga tatccagcga aggatgaaga aaacttgcga ggtgtcccga tgatctgaaa
    37921 aatggcagag tataatttat tcaacaggtt atattggaag caaatatttg aatattacat
    37981 attcagtgaa gaaatgcgta ataaaaatat acattgcgac t
//
LOCUS       DAPGUL010000036        37326 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.036, whole genome shotgun sequence.
ACCESSION   DAPGUL010000036 DAPGUL010000000
VERSION     DAPGUL010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 37326)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37326)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37326
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.036"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            202..1575
                     /gene="aroP"
                     /locus_tag="RHX21_001982"
     CDS             202..1575
                     /gene="aroP"
                     /locus_tag="RHX21_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transporter AroP"
                     /protein_id="HDV1987164.1"
                     /translation="MMEGQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSA
                     GPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGSFAGFASGWNYWVL
                     YVLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVKVFGEMEFWFAIIK
                     VIAVVAMIIFGGWLLFSGNGGPQATVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLE
                     LVGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLMPWTRVTADTSPFVLIF
                     HELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALASVDKRGVPV
                     NTILVSALVTALCVLINYLAPESAFGLLMALVVSALVINWAMISLAHMKFRRAKQEQG
                     VVTHFPALLYPLGNWICLLFMAAVLVIMLMTPGMAISVYLIPVWLIVLGIGYLFKEKT
                     AKAVKAH"
     gene            complement(1618..2472)
                     /gene="ampE"
                     /locus_tag="RHX21_001983"
     CDS             complement(1618..2472)
                     /gene="ampE"
                     /locus_tag="RHX21_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase regulator AmpE"
                     /protein_id="HDV1987165.1"
                     /translation="MTLFTTLLVLIFERLFKLGEHWQLDHRLEAFFRRVKHFSLGRTL
                     GMTIIAMGVTFLLLRALQGVLFNVPTLLVWLLIGLLCIGAGKVRLHYHAYLTAASRND
                     SHARATMAGELTMIHGVPAGCDEREYLRELQNALLWINFRFYLAPLFWLIVGGTWGPV
                     TLMGYAFLRAWQYWLARYQTPHHRLQSGIDAVLHVLDWVPVRLAGVVYALIGHGEKAL
                     PAWFASLGDFHTSQYQVLTRLAQFSLAREPHVDKVETPKAAVSMAKKTSFVVVVVIAL
                     LTIYGALV"
     gene            complement(2469..3020)
                     /gene="ampD"
                     /locus_tag="RHX21_001984"
     CDS             complement(2469..3020)
                     /gene="ampD"
                     /locus_tag="RHX21_001984"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,6-anhydro-N-acetylmuramyl-L-alanine amidase
                     AmpD"
                     /protein_id="HDV1987166.1"
                     /translation="MLLEQGWLVGARRVPSPHYDCRPDDETPTLLVVHNISLPPGEFG
                     GPWIDALFTGTIDPQAHPFFAEIAHLRVSAHCLIRRDGEIVQYVPFDKRAWHAGVSQY
                     QGRERCNDFSIGIELEGTDTLAYTDAQYQQLAAVTRALIDCYPDIAKNMTGHCDIAPD
                     RKTDPGPAFDWARFRVLVSKETT"
     gene            3108..4001
                     /gene="nadC"
                     /locus_tag="RHX21_001985"
     CDS             3108..4001
                     /gene="nadC"
                     /locus_tag="RHX21_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HDV1987167.1"
                     /translation="MPPRRYNPDTRRDELLERINLDIPGAVAQALREDLGGTVDANND
                     ITAKLLPENSRSHATVITRENGVFCGKRWVEEVFIQLAGDDVTIIWHVDDGDVINANQ
                     PLFELEGPSRVLLTGERTALNFVQTLSGVASKVRHYVELLEGTNTQLLDTRKTLPGLR
                     SALKYAVLCGGGANHRLGLSDAFLIKENHIIASGSVRQAVEKASWLHPDAPVEVEVEN
                     LEELDEALKAGADIIMLDNFETEQMREAVKRTNGKALLEVSGNVTDKTLREFAETGVD
                     FISVGALTKHVQALDLSMRFR"
     gene            4204..4644
                     /gene="ppdD"
                     /locus_tag="RHX21_001986"
     CDS             4204..4644
                     /gene="ppdD"
                     /locus_tag="RHX21_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent pilin"
                     /protein_id="HDV1987168.1"
                     /translation="MDKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQ
                     TFVPYRTAVELCALEHGGLDTCDGGSNGIPSPTTTRYVSAMSVAKGVVSLTGQESLNG
                     LSVVMTPGWDNANGVTGWTRNCNIQSDSALHQACEDVFRFDDAN"
     gene            4654..6039
                     /gene="gspE"
                     /locus_tag="RHX21_001987"
     CDS             4654..6039
                     /gene="gspE"
                     /locus_tag="RHX21_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspE"
                     /protein_id="HDV1987169.1"
                     /translation="MNIPQLTALCLRYHGVLLDASEEVVHVAVVDAPSHELLDALHFA
                     TTKRIEITCWTRQQMEGHASRTQQTLPVAVQEKHQPKAELLTRTLQSALEQRASDIHI
                     EPADNAYRIRLRIDGVLHPLPDVSPDAGVALTARLKVLGNLDIAEHRLPQDGQFTVEL
                     AGNAVSFRIATLPCRGGEKVVLRLLQQVSQALDVNTLGMQPLQLADFAHALQQPQGLV
                     LVTGPTGSGKTVTLYSALQTLNTADINICSVEDPVEIPIAGLNQTQIHPRAGLTFQGV
                     LRALLRQDPDVIMIGEIRDGETAEIAIKAAQTGHLVLSTLHTNSTCETLVRLQQMGVA
                     RWMLSSALTLVIAQRLVRKLCPHCRRQQGEPIHIPDNVWPSPLPHWQAPGCVHCYHGF
                     YGRTALFEVLPITPVIRQLISANTDVESLETHARQAGMRTLFENGCLAVEQGLTTFEE
                     LIRVLGMPHGE"
     gene            6029..7231
                     /gene="hofC"
                     /locus_tag="RHX21_001988"
     CDS             6029..7231
                     /gene="hofC"
                     /locus_tag="RHX21_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein transport protein HofC"
                     /protein_id="HDV1987170.1"
                     /translation="MASKQLWRWHGITGDGNAQDGMLWAESRALLLMALQQQMVTPLS
                     LKRIAINSAQWRGDKSAEVIHQLATLLKAGLTLSEGLALLAEQHPSKQWQALLQSLAH
                     DLEQGIAFSNALLPWSEVFPPLYQAMIRTGELTGKLDECCFELARQQKAQRQLTDKVK
                     SALRYPIIILAMAIMVVVAMLHFVLPEFAAIYKTFNTPLPALTQGIMTLADFSGEWSW
                     LLVLFGFLLAIANKLLMRRPTWLIVRQKLLLRIPIMGSLMRGQKLTQIFTILALTQSA
                     GITFLQGVESVRETMRCPYWVQLLTQIQHDISNGHPIWLALKNTGEFSPLCLQLVRTG
                     EASGSLDLMLDNLAHHHRDNTMALADNLAALLEPALLIITGGIIGTLVVAMYLPIFHL
                     GDAMSGMG"
     gene            complement(7266..8309)
                     /gene="guaC"
                     /locus_tag="RHX21_001989"
     CDS             complement(7266..8309)
                     /gene="guaC"
                     /locus_tag="RHX21_001989"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008461816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HDV1987171.1"
                     /translation="MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQSW
                     SGVPIIAANMDTVGTFSMASALASFDILTAVHKHYSVEEWQAFINNSSADVLKHVMVS
                     TGTSDADFEKTKQILDLNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVV
                     TGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVS
                     DGGCTTPGDVAKAFGGGADFVMLGGMLAGHEESGGRIVEENGEKFMLFYGMSSESAMK
                     RHVGGVAEYRAAEGKTVKLPLRGPVENTARDILGGLRSACTYVGASRLKELTKRTTFI
                     RVQEQENRIFNNL"
     gene            complement(8465..8509)
                     /locus_tag="RHX21_001990"
     CDS             complement(8465..8509)
                     /locus_tag="RHX21_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987172.1"
                     /translation="MIIKTLKMSARKRN"
     gene            8534..9154
                     /gene="coaE"
                     /locus_tag="RHX21_001991"
     CDS             8534..9154
                     /gene="coaE"
                     /locus_tag="RHX21_001991"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HDV1987173.1"
                     /translation="MRYIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGA
                     PALHAIADHFGANMIAADGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQQ
                     ATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQA
                     TREARLAVADDVIDNNGAPDAIASDVARLHAHYLQLASQFVSQEKP"
     gene            9154..9897
                     /gene="zapD"
                     /locus_tag="RHX21_001992"
     CDS             9154..9897
                     /gene="zapD"
                     /locus_tag="RHX21_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapD"
                     /protein_id="HDV1987174.1"
                     /translation="MQTQVLFEHPLNEKMRTWLRIEFLIQQLTVNLPIVDHAGALHFF
                     RNVSELLDVFERGEVRTELLKELDRQQRKLQTWIGVPGVDQSRIEALIQQLKAAGSVL
                     ISAPRIGQFLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLPQAQRDSQVETWIAS
                     LNPLTQALTMVLDLIRQSAPFRKQTSLNGFYQDNGGDADLLRLNLSLDSQLYPQISGH
                     KSRFAIRFMPLDTENGQVPERLDFELACC"
     gene            9907..10104
                     /gene="yacG"
                     /locus_tag="RHX21_001993"
     CDS             9907..10104
                     /gene="yacG"
                     /locus_tag="RHX21_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor YacG"
                     /protein_id="HDV1987175.1"
                     /translation="MSETITVNCPTCGKTVVWGEISPFRPFCSKRCQLIDLGEWAAEE
                     KRIPSSGDLSESDDWSEEPKQ"
     gene            complement(10204..10593)
                     /gene="mutT"
                     /locus_tag="RHX21_001994"
     CDS             complement(10204..10593)
                     /gene="mutT"
                     /locus_tag="RHX21_001994"
                     /EC_number="3.6.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase MutT"
                     /protein_id="HDV1987176.1"
                     /translation="MKKLQIAVGIIRNENNEIFITRRAADAHMANKLEFPGGKIEMGE
                     TPEQAVVRELQEEVGITPQHFSLFEKLEYEFPDRHITLWFWLVESWEGEPWGKEGQPG
                     EWMSLVGLNADDFPPANEPVIAKLKRL"
     gene            complement(10653..13358)
                     /gene="secA"
                     /locus_tag="RHX21_001995"
     CDS             complement(10653..13358)
                     /gene="secA"
                     /locus_tag="RHX21_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDV1987177.1"
                     /translation="MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELK
                     GKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEM
                     RTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPG
                     MPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDE
                     ARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTE
                     RGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVI
                     IVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTG
                     TADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQ
                     PVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAG
                     RGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLEAGGLHIIGTERHESRR
                     IDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVT
                     KAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIRED
                     VFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERIL
                     AQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKD
                     PKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQ
                     LSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ"
     gene            complement(13420..13932)
                     /gene="secM"
                     /locus_tag="RHX21_001996"
     CDS             complement(13420..13932)
                     /gene="secM"
                     /locus_tag="RHX21_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414639.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secA regulator SecM"
                     /protein_id="HDV1987178.1"
                     /translation="MSGILTRWRQFGKRYFWPHLLLGMVAASLGLPALSNAAEPNAPA
                     KATTRNHEPSAKVNFGQLALLEANTRRPNSNYSVDYWHQHAIRTVIRHLSFAMAPQTL
                     PVAEESLPLQAQHLALLDTLSALLTQEGTPSEKGYRIDYAHFTPQAKFSTPVWISQAQ
                     GIRAGPQRLT"
     gene            complement(14163..15080)
                     /gene="lpxC"
                     /locus_tag="RHX21_001997"
     CDS             complement(14163..15080)
                     /gene="lpxC"
                     /locus_tag="RHX21_001997"
                     /EC_number="3.5.1.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-acyl-N-acetylglucosamine deacetylase"
                     /protein_id="HDV1987179.1"
                     /translation="MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDL
                     NPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIP
                     IMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTID
                     FNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVV
                     DDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVL
                     AKQEAWEYVTFQDDAELPLAFKAPSAVLA"
     gene            complement(15181..16332)
                     /gene="ftsZ"
                     /locus_tag="RHX21_001998"
     CDS             complement(15181..16332)
                     /gene="ftsZ"
                     /locus_tag="RHX21_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HDV1987180.1"
                     /translation="MFEPMELTNDAVIKVIGVGGGGGNAVEHMVRERIEGVEFFAVNT
                     DAQALRKTAVGQTIQIGSGITKGLGAGANPEVGRNAADEDRDALRAALEGADMVFIAA
                     GMGGGTGTGAAPVVAEVAKDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSL
                     ITIPNDKLLKVLGRGISLLDAFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMS
                     EMGYAMMGSGVASGEDRAEEAAEMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFE
                     TVGNTIRAFASDNATVVIGTSLDPDMNDELRVTVVATGIGMDKRPEITLVTNKQVQQP
                     VMDRYQQHGMAPLTQEQKPVAKVVNDNAPQTAKEPDYLDIPAFLRKQAD"
     gene            complement(16393..17655)
                     /gene="ftsA"
                     /locus_tag="RHX21_001999"
     CDS             complement(16393..17655)
                     /gene="ftsA"
                     /locus_tag="RHX21_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HDV1987181.1"
                     /translation="MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSR
                     GMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVYLALSGKHISCQNEIGMVPISEE
                     EVTQEDVENVVHTAKSVRVRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHL
                     ITCHNDMAKNIVKAVERCGLKVDQLIFAGLASSYSVLTEDERELGVCVVDIGGGTMDI
                     AVYTGGALRHTKVIPYAGNVVTSDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVE
                     VPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNEEILQLQEKLRQQGVKHHLAAGIVL
                     TGGAAQIEGLAACAQRVFHTQVRIGAPLNITGLTDYAQEPYYSTAVGLLHYGKESHLN
                     GEAEVEKRVTASVGSWIKRLNSWLRKEF"
     gene            complement(17652..18482)
                     /gene="ftsQ"
                     /locus_tag="RHX21_002000"
     CDS             complement(17652..18482)
                     /gene="ftsQ"
                     /locus_tag="RHX21_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ"
                     /protein_id="HDV1987182.1"
                     /translation="MSQAALNTRNSEEEVSSRRNNGTRLAGILFLLTVLTTVLVSGWV
                     VLGWMEDAQRLPLSKLVLTGERHYTRNDDIRQSILALGEPGTFMTQDVNIIQTQIEQR
                     LPWIKQVSVRKQWPDELKIHLVEYVPIARWNDQHMVDAEGNTFSVPPDRTSKQVLPML
                     YGPEGSANEVLQGYREMGQMLAKDRFTLKEAAMTARRSWQLTLNNDIKLNLGRGDTMK
                     RLARFVELYPVLQQQAQTDGKRISYVDLRYDSGAAVGWAPLPPEESTQQQNQAQAEQQ
                     "
     gene            complement(18484..19404)
                     /gene="ddlB"
                     /locus_tag="RHX21_002001"
     CDS             complement(18484..19404)
                     /gene="ddlB"
                     /locus_tag="RHX21_002001"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDV1987183.1"
                     /translation="MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKE
                     VDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKL
                     LWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAE
                     NALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLS
                     DETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPG
                     MTSHSLVPMAARQAGMSFSQLVVRILELAD"
     gene            complement(19397..20872)
                     /gene="murC"
                     /locus_tag="RHX21_002002"
     CDS             complement(19397..20872)
                     /gene="murC"
                     /locus_tag="RHX21_002002"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HDV1987184.1"
                     /translation="MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGY
                     QISGSDLAPNPVTQQLMNLGATIYFNHRPENVRDASVVVVSSAISADNPEIVAAHEAR
                     IPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAG
                     VHARLGHGRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFL
                     HNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLR
                     QDKEPMRVTLNAPGRHNALNAAAAVAVATEEGIDDEAILRALESFQGTGRRFDFLGEF
                     PLEPVNGKSGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRFTRTRDLYD
                     DFANVLTQVDTLLMLEVYPAGEAPIPGADSRSLCRTIRGRGKIDPILVPDPAQVAEML
                     APVLTGNDLILVQGAGNIGKIARSLAEIKLKPQTPEEEQHD"
     gene            complement(20926..21993)
                     /gene="murG"
                     /locus_tag="RHX21_002003"
     CDS             complement(20926..21993)
                     /gene="murG"
                     /locus_tag="RHX21_002003"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDV1987185.1"
                     /translation="MSGQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADR
                     MEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGM
                     GGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGN
                     PVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQS
                     GKGSQQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPA
                     LFVPFQHKDRQQYWNALPLEKAGAAKIIEQPQLSVDAVANTLAGWSRETLLTMAERAR
                     AASIPDATERVANEVSRAARA"
     gene            complement(21990..23234)
                     /gene="ftsW"
                     /locus_tag="RHX21_002004"
     CDS             complement(21990..23234)
                     /gene="ftsW"
                     /locus_tag="RHX21_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsW"
                     /protein_id="HDV1987186.1"
                     /translation="MRLSLPRLKMPRLPGFSILVWISTALKGWVMGSREKDTDSLIMY
                     DRTLLWLTFGLAAIGFIMVTSASMPIGQRLTNDPFFFAKRDGVYLILAFILAIITLRL
                     PMEFWQRYSATMLLGSIILLMIVLVVGSSVKGASRWIDLGLLRIQPAELTKLSLFCYI
                     ANYLVRKGDEVRNNLRGFLKPMGVILVLAVLLLAQPDLGTVVVLFVTTLAMLFLAGAK
                     LWQFIAIIGMGISAVVLLILAEPYRIRRVTAFWNPWEDPFGSGYQLTQSLMAFGRGEL
                     WGQGLGNSVQKLEYLPEAHTDFIFAIIGEELGYVGVVLALLMVFFVAFRAMSIGRKAL
                     EIDHRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIM
                     MLLRIDYETRLEKAQAFVRGSR"
     gene            complement(23234..24550)
                     /gene="murD"
                     /locus_tag="RHX21_002005"
     CDS             complement(23234..24550)
                     /gene="murD"
                     /locus_tag="RHX21_002005"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HDV1987187.1"
                     /translation="MADYQGKNVVIIGLGLTGLSCVDFFLARGLTPRVMDTRMTPPGL
                     DKLPEAVERHTGSLNDEWLMAADLIVASPGIALAHPSLSAAADAGIEIVGDIELFCRE
                     AQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDAECELYVLELS
                     SFQLETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRIYENAKVCVVNADDALT
                     MPIRGADERCVSFGVNMGDYHLNHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAA
                     LALADAAGLPRASSLKALTTFTGLPHRFEVVLEHNGVRWINDSKATNVGSTEAALNGL
                     QVDGTLHLLLGGDGKSADFSPLARYLNGDNVRLYCFGRDGAQLAALRPEVAEQTETME
                     QAMRLLAPRVQPGDMVLLSPACASLDQFKNFEQRGNEFARLAKELG"
     gene            complement(24553..25635)
                     /gene="mraY"
                     /locus_tag="RHX21_002006"
     CDS             complement(24553..25635)
                     /gene="mraY"
                     /locus_tag="RHX21_002006"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HDV1987188.1"
                     /translation="MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRM
                     IAHLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVL
                     VVLVGYGVIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLAGKDTPATQL
                     VVPFFKDVMPQLGLFYILLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWA
                     TGNMNFASYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGA
                     LGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWP
                     EPRVIVRFWIISLMLVLIGLATLKVR"
     gene            complement(25629..26987)
                     /gene="murF"
                     /locus_tag="RHX21_002007"
     CDS             complement(25629..26987)
                     /gene="murF"
                     /locus_tag="RHX21_002007"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HDV1987189.1"
                     /translation="MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALK
                     GERFDAHDFADQAKAGGAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARV
                     VALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELG
                     ANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMN
                     ADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLP
                     LPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYN
                     ANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESEACHVQVGEAAKAAGIDRVLSVGK
                     QSHAISTASGVGEHFADKTALITRLKSLIAEQQVITILVKGSRSAAMEEVVRALQENG
                     TC"
     gene            complement(26984..28471)
                     /gene="murE"
                     /locus_tag="RHX21_002008"
     CDS             complement(26984..28471)
                     /gene="murE"
                     /locus_tag="RHX21_002008"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HDV1987190.1"
                     /translation="MADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGH
                     QADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRFY
                     HEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGETSAVMGTVGNGLLGKVIPTENTTG
                     SAVDVQHELAGLVEQGATFCAMEVSSHGLVQHRVAALKFAASVFTNLSRDHLDYHGDM
                     EHYEAAKWLLYSEHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKA
                     IDVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALATLLALGYPLADLLKTAA
                     RLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDK
                     GKRPLMGAIAEEFADVAVVTDDNPRTEEPRAIINDILAGMLDAGHAKVMEGRAEAVTC
                     AVMQAKENDVVLVAGKGHEDYQIVGNQRLDYSDRVTVARLLGVIA"
     gene            complement(28458..30224)
                     /gene="ftsI"
                     /locus_tag="RHX21_002009"
     CDS             complement(28458..30224)
                     /gene="ftsI"
                     /locus_tag="RHX21_002009"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase FtsI"
                     /protein_id="HDV1987191.1"
                     /translation="MKAAAKTQKPKRQEEHANFISWRFALLCGCILLALAFLLGRVAW
                     LQVISPDMLVKEGDMRSLRVQQVSTSRGMITDRSGRPLAVSVPVKAIWADPKEVHDAG
                     GISVGDRWKALANALNIPLDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIH
                     LREESRRYYPSGEVTAHLIGFTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVI
                     EDISSTDSQAAHNLALSIDERLQALVYRELNNAVAFNKAESGSAVLVDVNTGEVLAMA
                     NSPSYNPNNLSGTPKEAMRNRTITDVFEPGSTVKPMVVMTALQRGVVRENSVLNTIPY
                     RINGHEIKDVARYSELTLTGVLQKSSNVGVSKLALAMPSSALVDTYSRFGLGKATNLG
                     LVGERSGLYPQKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSYGIYRPLSITKVD
                     PPVPGERVFPESIVRTVVHMMESVALPGGGGVKAAIKGYRIAIKTGTAKKVGPDGRYI
                     NKYIAYTAGVAPASQPRFALVVVINDPQAGKYYGGAVSAPVFGAIMGGVLRTMNIEPD
                     ALTTGDKNEFVINQGEGTGGRS"
     gene            complement(30240..30605)
                     /gene="ftsL"
                     /locus_tag="RHX21_002010"
     CDS             complement(30240..30605)
                     /gene="ftsL"
                     /locus_tag="RHX21_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000625658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HDV1987192.1"
                     /translation="MISRVTEALSKVKGSMGSHERHALPGVIGDDLLRFGKLPLCLFI
                     CIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSRVERIAT
                     EKLQMQHVDPSQENIVVQK"
     gene            complement(30602..31543)
                     /gene="rsmH"
                     /locus_tag="RHX21_002011"
     CDS             complement(30602..31543)
                     /gene="rsmH"
                     /locus_tag="RHX21_002011"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HDV1987193.1"
                     /translation="MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQ
                     LGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDL
                     GVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERF
                     AKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEE
                     IEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPITEEQLKKL
                     GGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA"
     gene            complement(31545..32003)
                     /gene="mraZ"
                     /locus_tag="RHX21_002012"
     CDS             complement(31545..32003)
                     /gene="mraZ"
                     /locus_tag="RHX21_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020325403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HDV1987194.1"
                     /translation="MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIHHPC
                     LLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHA
                     GLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL"
     gene            complement(32605..33609)
                     /gene="cra"
                     /locus_tag="RHX21_002013"
     CDS             complement(32605..33609)
                     /gene="cra"
                     /locus_tag="RHX21_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite repressor/activator"
                     /protein_id="HDV1987195.1"
                     /translation="MKLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVEKVMAVVRE
                     HNYHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQ
                     PDNEMRCIEHLLQRQVDAIIVSTSLPPEHPFYQRWANDPFPIVALDRALDREHFTSVV
                     GADQDDAEMLAEELRKFPAETVLYLGALPELSVSFLREQGFRTAWKDDPREVHFLYAN
                     SYEREAAAQLFEKWLETHPMPQALFTTSFALLQGVMDVTLRRDGKLPSDLAIATFGDN
                     ELLDFLQCPVLAVAQRHRDVAERVLEIVLASLDEPRKPKPGLTRIKRNLYRRGVLSRS
                     "
     gene            complement(33691..33777)
                     /locus_tag="RHX21_002014"
     CDS             complement(33691..33777)
                     /locus_tag="RHX21_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fruR/shl operon leader peptide"
                     /protein_id="HDV1987196.1"
                     /translation="MRNLQPNMSRWAFFAKSVGTWNKSSCRS"
     gene            complement(33789..34280)
                     /gene="ilvN"
                     /locus_tag="RHX21_002015"
     CDS             complement(33789..34280)
                     /gene="ilvN"
                     /locus_tag="RHX21_002015"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001563086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HDV1987197.1"
                     /translation="MRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLS
                     RMTIQTVGDEKVLEQIEKQLHKLVDVLRVSELGQGAHVEREIMLVKIQASGYGRDEVK
                     RNTEIFRGQIIDVTPSLYTVQLAGTSDKLDAFLASIRDVAKIVEVARSGVVGLSRGDK
                     IMR"
     gene            complement(34283..36007)
                     /gene="ilvI"
                     /locus_tag="RHX21_002016"
     CDS             complement(34283..36007)
                     /gene="ilvI"
                     /locus_tag="RHX21_002016"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020079613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 3 large subunit"
                     /protein_id="HDV1987198.1"
                     /translation="MEMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGID
                     HILVRHEQAAVHMADGLARATGEVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQ
                     VATSLIGYDAFQECDMVGISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVD
                     LPKDILNPANKLPYVWPESVSMRSYNPTTTGHKGQIKRALQTLVAAKKPVVYVGGGAI
                     TAGCHQQLKETVEALNLPVVSSLMGLGAFPATHRQALGMLGMHGTYEANMTMHNADVI
                     FAVGVRFDDRTTNNLAKYCPNATVLHIDIDPTSISKTVTADIPIVGDARQVLEQMLEL
                     LSQESAHQPLDEIRDWWQQIEQWRARQCLKYDTHSEKIKPQAVIETLWRLTKGDAYVT
                     SDVGQHQMFAALYYPFDKPRRWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGS
                     IQMNIQELSTALQYELPVLVVNLNNRYLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLA
                     EAYGHVGIQISHPHELESKLSEALEQVRNNRLVFVDVTVDGSEHVYPMQIRGGGMDEM
                     WLSKTERT"
     gene            36126..36170
                     /locus_tag="RHX21_002017"
     CDS             36126..36170
                     /locus_tag="RHX21_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987199.1"
                     /translation="MKRNDKILHYEGLN"
     gene            complement(36325..37269)
                     /gene="leuO"
                     /locus_tag="RHX21_002018"
     CDS             complement(36325..37269)
                     /gene="leuO"
                     /locus_tag="RHX21_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414618.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LeuO"
                     /protein_id="HDV1987200.1"
                     /translation="MPEVQTDHSETAELSKPQLRMVDLNLLTVFDAVMQEQNITRAAH
                     VLGMSQPAVSNAVARLKVMFNDELFVRYGRGIQPTARAFQLFGSVRQALQLVQNELPG
                     SGFEPASSERVFHLCVCSPLDSILTSQIYNHIEQIAPNIHVMFKSSLNQNTEHQLRYQ
                     ETEFVISYEDFHRPEFTSVPLFKDEMVLVASKNHPTIKGPLLKHDVYNEQHAAVSLDR
                     FASFSQPWYDTVDKQASIAYQGMAMMSVLSVVSQTHLVAIAPRWLAEEFAESLELQVL
                     PLPLKQNSRTCYLSWHEAAGRDKGHQWMEEQLVSICKR"
BASE COUNT         8954 a        10430 c         9140 g         8802 t
ORIGIN      
        1 tttcttttta agcaactcat cttcaaccat gcataaagcg ggtgcattcg ctgccgcata
       61 ccattattct tgatctgacg gaagtctttt tgtagcaatt caaacttctt tgatgtaaac
      121 aaattaatac aacaaacgga attgcaaact tacacacgca tcactgcgta gatcaaaaaa
      181 acaaccaccg cacgaggttt catgatggaa ggtcaacagc acggcgagca gctaaagcgc
      241 ggccttaaaa accgccatat tcagcttatc gcgctgggtg gcgcgatagg gaccgggtta
      301 ttcctgggta gcgcctccgt aatacagtcc gcagggccag ggattatcct gggttacgcc
      361 attgctggtt ttatcgcctt tctgatcatg cgtcagctgg gtgaaatggt ggtcgaagaa
      421 cctgtcgcag gctcctttag ccactttgct tataaatact ggggcagttt tgccggtttc
      481 gcctctggct ggaactactg ggtactgtac gttttagttg ccatggctga gctgactgcc
      541 gtgggtaaat acattcagtt ctggtatccg gaaatcccca cctgggtttc tgccgccgta
      601 ttctttgtgg tgattaacgc catcaacctg accaacgtta aagtgtttgg cgagatggag
      661 ttctggtttg ccattatcaa agttatcgcg gtggtagcga tgatcatctt cggcggctgg
      721 ctgctattca gtggcaacgg cggcccgcag gcgaccgtta gcaacctgtg ggatcagggt
      781 ggtttcctgc cgcacggctt caccgggctg gtgatgatga tggcgattat catgttctcg
      841 ttcggtggtc tggaactggt ggggatcacc gcagcagaag ctgataaccc ggagcaaagt
      901 ataccgaaag caactaacca ggttatctac cgcatcctga ttttctatat tggttcgtta
      961 gccgttctgc tctcactgat gccgtggacc cgcgttaccg ccgataccag tccgtttgtg
     1021 ctgatcttcc acgagttagg cgataccttt gtggcgaatg cgctgaacat cgtggtactg
     1081 actgcggcgc tctccgtgta caacagctgc gtatattgca acagccgtat gctgtttggt
     1141 ctggcacaac agggtaatgc gccaaaagcg ctggcgtctg tcgataaacg tggtgtacca
     1201 gtaaatacca ttctggtgtc tgcactggta acggcgttgt gcgtactgat taactacctt
     1261 gccccagagt ccgctttcgg actgttaatg gcgctggtgg tatctgcact ggtaatcaac
     1321 tgggcgatga ttagcctggc gcatatgaaa ttccgtcgcg ccaagcagga acaaggcgtg
     1381 gtaactcact tccctgctct gctttatccg ctgggtaact ggatctgcct gctgtttatg
     1441 gcggcggtac tggtgattat gctgatgacc ccaggaatgg cgatttcggt atacctgatc
     1501 ccggtatggc tgatcgtgtt aggtatcggc tatctgttta aagagaaaac cgccaaagcc
     1561 gtaaaagcgc attaatctct ctacgccctc acccgtacag ggtgagggca ataatcttta
     1621 caccaacgcc ccgtaaatcg tcagtagtgc aatcaccacc acgaccacga acgaggtttt
     1681 cttcgccatt gaaaccgctg ccttcggcgt ctccacctta tcgacatgcg gttcacgcgc
     1741 cagagagaac tgcgccagac gcgttaacac ctgatactgc gaagtatgga aatcacccag
     1801 cgaagcaaac caggctggta acgctttctc accatgaccg atcaaggcat ataccacacc
     1861 cgcaagacga accggcaccc aatccagtac atgaagcacg gcatcaatgc cggactgtaa
     1921 acgatgatgc ggcgtctgat atcgcgccag ccagtattgc catgcacgca aaaacgcata
     1981 ccccatcagc gtaacgggtc cccaggttcc ccccacaatc agccagaaca gcggtgcaag
     2041 ataaaaacga aagttaatcc acagcaatgc attttgcagc tcacgcaaat actcacgttc
     2101 gtcgcagcct gccgggacgc cgtgaatcat ggtgagttcg ccagccatcg tggcacgggc
     2161 atggctatca ttacgtgaag cagctgtcag ataagcatga taatgaagac gaactttacc
     2221 tgcgccaata cacagcaaac caatcagcag ccacaccagt agcgtgggaa cgttgaacaa
     2281 tactccctgc aatgcgcgta acagtaaaaa agtcacgccc atcgcaataa tggtcatgcc
     2341 taacgtgcgc ccgagagaaa aatgtttcac ccgccgaaag aacgcttcaa gacgatgatc
     2401 aagctgccag tgctcgccca acttaaacag gcgctcgaaa attaacacca gtaaggttgt
     2461 aaatagcgtc atgttgtctc cttgctgacc agcacacgaa accgtgccca atcaaatgca
     2521 ggaccgggat cggttttccg atccggcgca atatcacaat ggcccgtcat gtttttagcg
     2581 atatccggat agcaatcaat cagtgcccgc gtaaccgccg caagctgttg atactgcgca
     2641 tcggtatacg ccagcgtatc ggtgccttca agctcaatcc caatagaaaa atcattgcag
     2701 cgttcgcgcc cctgatactg agagactccc gcatgccatg cacgtttatc gaaaggaaca
     2761 tactggacta tttcaccatc acggcgaatc aaacagtgag cggagacgcg caaatgggcg
     2821 atttcagcaa agaaaggatg tgcctgcgga tcaatagttc cagtgaataa tgcgtcgatc
     2881 cacggaccgc caaactcgcc tggcggcagg ctaatattgt gcaccaccag cagggtgggt
     2941 gtttcgtcat ccgggcggca atcgtaatgt ggtgagggaa cgcggcgcgc gccaaccagc
     3001 cacccctgtt ctaacaacat gcaggatctc cttatatgtg gtgctaatac ccggttcaga
     3061 gtagcatgtt tctaccttat gattcgttag ctatctggag ttttaacatg ccgcctcgcc
     3121 gctataaccc tgacacccga cgtgacgagc tgctggaacg cattaatctc gatatccccg
     3181 gcgcggtggc ccaggcgctg cgggaagatt taggcggaac agtcgatgcc aacaatgata
     3241 ttacggcaaa acttttaccg gaaaattctc gctctcatgc cacggtgatc acccgcgaga
     3301 atggcgtctt ttgcggcaaa cgctgggttg aagaggtgtt tattcaactg gcaggcgacg
     3361 atgtcaccat aatctggcat gtggatgacg gcgatgtcat caacgccaat caacccttgt
     3421 tcgaacttga aggcccatcc cgcgtgctgt taacgggcga acgcactgcg cttaattttg
     3481 tgcaaaccct ttcaggagtt gccagtaagg tacgccacta tgtcgaattg ctggaaggca
     3541 ccaacacgca gttgttggat acgcgcaaaa ccttacccgg cctgcgttca gctctgaaat
     3601 acgcggttct ttgcggcggc ggagcgaatc accgtctggg gctttctgat gccttcctga
     3661 tcaaagaaaa ccatattatt gcctccggct cagtgcgcca ggcggtcgaa aaagcgtcct
     3721 ggctgcaccc ggatgcgcca gtagaagtcg aagtagagaa tctggaagaa cttgatgaag
     3781 ccctgaaagc aggagccgat atcatcatgc tggataactt cgaaacagaa cagatgcgcg
     3841 aagccgtcaa acgcaccaac ggcaaggcgc tactggaagt gtctggcaac gtcactgaca
     3901 aaacactgcg tgaatttgcc gaaacgggcg tggactttat ctccgtcggt gcgctaacta
     3961 aacacgtaca agcactcgac ctttcaatgc gttttcgcta atagttgaca gatttatccg
     4021 ctccatcgcg ggcggataat ctccccttcc ccaactttct tcgtaacgcc tcgcaaattt
     4081 cttgtctttc gctgcaacga aataaaaaac ctcggaatct gctttcccgt ttcgtttttt
     4141 gcccctcgcc tgtgctgatg gcgtttgcca aagtagcgcc aactaaatca aggagcgaaa
     4201 cagatggaca agcaacgcgg ttttacactt atcgaactga tggtggttat tggcatcatt
     4261 gccattttaa gcgccattgg tattcccgct tatcaaaact acctgcgcaa agccgcactc
     4321 accgacatgc tacaaacctt tgtgccttac cgtaccgccg tagagttgtg cgcgctggaa
     4381 catggtggat tagatacctg cgacggtggc agcaatggca ttccctcgcc taccaccacc
     4441 cgctatgttt cagccatgag tgtggcaaag ggcgtggtgt cgctgaccgg gcaagaaagt
     4501 ctcaatgggc taagcgtcgt catgacaccg ggttgggata acgcaaacgg cgtcaccggc
     4561 tggacgcgca actgcaatat tcaaagtgac agcgcattgc atcaagcctg cgaagatgtc
     4621 ttccgctttg atgacgccaa ctaaggagcg gcaatgaata ttccacagct cactgccctg
     4681 tgtctgcgtt atcatggagt cttgctggat gccagcgaag aggtggttca tgttgcggta
     4741 gtcgatgcac cttcgcatga gctactggac gcattgcatt tcgctaccac caaacgtatt
     4801 gagatcacct gctggacgcg ccaacaaatg gaaggtcacg ccagtcgcac acaacagaca
     4861 ttgcccgtag ctgttcagga gaagcatcag cccaaagcag agttgctaac tcgaacgtta
     4921 caatctgcgc tggaacaacg cgcgtctgat attcatatcg aaccagcgga caatgcctac
     4981 cgcatccgct tgcgtatcga cggcgtattg catcctttac cggatgtttc accggatgcc
     5041 ggagtcgcat taaccgccag attaaaagtg ctgggaaacc tggatattgc ggaacatcgc
     5101 ctgccgcagg acgggcaatt cactgtcgaa ctggcaggaa acgccgtctc atttcgtatt
     5161 gcgaccttac catgtcgggg tggtgaaaag gtggtattaa ggttgttaca gcaggtgagc
     5221 caggcactgg atgtcaacac gcttggaatg cagccgttac aactggcgga ctttgctcat
     5281 gccttgcaac aaccacaggg actggtgctg gtaactggcc ctacaggcag cggcaaaacg
     5341 gtcacgcttt atagtgccct gcaaacgctg aataccgctg acattaatat ttgtagcgtc
     5401 gaagatccgg ttgagatccc catagccgga ctaaaccaga cgcaaatcca tccgcgtgcc
     5461 ggactcacct ttcagggcgt gttgcgtgcg ttattgcgcc aggatcctga cgtcatcatg
     5521 atcggagaga tccgcgatgg cgaaacagca gagatcgcta ttaaagcggc gcaaactggt
     5581 cacctggtgt tgtctaccct acacactaat tccacctgcg aaacgctggt acgtttacag
     5641 caaatggggg tcgcccgctg gatgctatca tcggcgctta cgctggtaat agcccagcgt
     5701 ctggtacgca aactttgccc acattgtcgc cggcagcaag gggagcccat ccacattcca
     5761 gacaatgtat ggccatcgcc actgccccac tggcaggcac ccggttgtgt acattgctac
     5821 cacggttttt atggtcgtac ggccttattt gaagttctgc ccataacgcc ggtcattcgt
     5881 cagcttattt ccgctaatac cgacgttgaa tcgctggaaa cgcacgcacg acaggcgggt
     5941 atgcgtacgc tttttgaaaa cggctgcctg gccgtggagc aaggcttaac cacctttgaa
     6001 gagttaatcc gcgtactggg gatgccgcat ggcgagtaag caactctggc gctggcatgg
     6061 cataaccggc gacggcaatg cgcaagatgg gatgctatgg gcagagagcc gtgctttgct
     6121 gctcatggca ctacagcaac agatggttac cccacttagc ctgaagcgaa tcgccatcaa
     6181 ttctgcgcag tggcgaggag ataaaagcgc ggaagtcatt catcaactgg cgacgctact
     6241 caaagccggg ttaacgcttt ctgaagggct ggcactgctg gcggaacagc atcccagtaa
     6301 gcaatggcaa gcgttgctgc aatcgctggc gcacgatctc gaacagggca ttgctttttc
     6361 caatgcctta ttaccctggt cagaggtatt tccgccactc tatcaggcga tgatccgcac
     6421 gggtgaactg accggtaagc tggatgaatg ctgctttgaa ctggcgcgtc agcaaaaagc
     6481 ccagcgtcag ttgaccgaca aagtgaaatc agcgttacgt tatcccatca tcattttagc
     6541 gatggcaatc atggtggttg tggcaatgct gcattttgtt ctgccggagt ttgccgctat
     6601 ctataagacc ttcaacaccc cactaccggc actaacgcag gggatcatga cgctggcaga
     6661 ctttagtggc gaatggagct ggctgctggt gttgttcggc tttctgctgg cgatagccaa
     6721 taagttgctg atgcgccgac cgacctggct tatagtgcgg cagaaattgc tgttacgaat
     6781 cccgattatg ggttcactga tgcggggaca aaaactcacg cagatcttta cgattctggc
     6841 gctgacacaa agtgcaggca ttactttttt gcagggcgta gagagcgtca gagaaacaat
     6901 gcgctgcccg tactgggtgc aacttctgac acaaatccag cacgatatca gtaacggtca
     6961 tcccatctgg ctggcgctaa aaaataccgg ggagtttagc ccgctctgtt tgcaattagt
     7021 gagaacagga gaggcatccg gctcgctgga cctcatgtta gacaacctcg cccatcatca
     7081 tcgggataac acaatggcgc tggcggataa cctcgcagcc ttactggaac cggcgttgct
     7141 gatcataacg ggaggaatta tcggtacgct ggtggtggcg atgtatctgc caattttcca
     7201 tttaggcgat gcgatgagtg ggatgggata acgctggcgt gttgctccac accagcgttg
     7261 gaagattaca ggttgttgaa gatgcggttt tcttgttcct gcacacggat aaatgtggtg
     7321 cgcttggtca gttctttcag gcgtgaagcc ccaacgtatg tacaagctga acgcaggccg
     7381 cccaaaatat cacgcgcggt attttcaacc gggcctcgca gcggcagctt aacggtttta
     7441 ccttctgctg cgcgatattc cgcaacgccg ccaacgtgac gtttcatcgc agactcggag
     7501 ctcatgccgt agaacagcat aaatttctcg ccgttctcct caacgatgcg accgccgctc
     7561 tcttcgtggc ccgccagcat gccgccaagc atgacgaaat cggcaccgcc gccaaaggct
     7621 tttgcgacat cgcccggcgt ggtgcagcca ccgtcgctga cgatcattcc gcccagaccg
     7681 tgcgccgcat cggcacattc gattaccgca gaaagctgcg gataaccgac gcctgttttg
     7741 acgcgagttg tgcaaacaga acctgggcca atgccaactt taacgatatc agcaccggag
     7801 aggataagct cctcacacat ttcaccagtc actacgttgc cagcacaaat ggttttggtc
     7861 ggccacgctt cacgcgcttt cgcaacgaac tgcacgaagt gttcggaata accattcgcc
     7921 acatcaatac aaacgaagtt taatgccggg ttcaggtcga gaatctgttt agttttttcg
     7981 aaatccgcat cagacgtacc ggtagaaacc atcacatgtt tcagcacatc agcggaagaa
     8041 ttgttgataa acgcttgcca ctcttcgaca gaatagtgtt tatgcacagc agtcaaaata
     8101 tcaaaagaag ccagcgcaga ggccatagaa aatgtaccta cggtgtccat atttgcggcg
     8161 ataattggca cgccggacca gctctgacct gaatgtttga aggtgaattg acgttccagt
     8221 tcaacatcgg aacggctttt aagagtggag cgtttagggc ggatgagaac gtctttaaaa
     8281 cctaacttca gatcttcttc aatacgcatg tgcggattcc tggggttaat ggctataagg
     8341 gtaagagcgc aactccagtg acgctatcat acgcactaat caatgcggcg caagactgcg
     8401 aaattgtctt tttttacgct acaatcccat aaatttacct ggtaaatagt gagcgaacgt
     8461 ttcatcaatt tcgctttcgt gcactcattt ttaacgtttt gataatcatg atgaattccc
     8521 gggaatataa attatgaggt atatagttgc cttaacggga ggcattggca gtggcaagag
     8581 taccgttgcc aatgcgtttg ctgatctcgg aattaacgtc attgatgccg atattattgc
     8641 gcgtcaggtg gttgaaccag gtgcacctgc gctacatgcc attgctgatc actttggcgc
     8701 taacatgatt gctgctgatg gaacattgca gcgccgggcc ttgcgcgagc ggatcttcgc
     8761 caacccggaa gagaaaaact ggcttaacgc cctgctgcat ccgctgattc agcaagagac
     8821 gcaacaccag atccagcaag ctacttcccc ctatgtactg tgggttgtgc cattgctggt
     8881 agaaaactca ctgtataaaa aagcgaatcg agtgctggtg gtggatgtca gcccagaaac
     8941 gcaacttaag cgcaccatgc agcgcgatga tgtaactcgc gagcatgtcg aacaaatcct
     9001 tgctgctcag gcaacgcgcg aagcccgcct tgccgtggca gatgacgtca ttgataataa
     9061 cggcgcaccg gatgctatcg catcggatgt tgcccgcctg cacgcacact atttgcagct
     9121 tgcgtcgcag tttgtctcac aggaaaaacc gtaatgcaga cccaggtcct ttttgaacat
     9181 ccactaaatg aaaaaatgcg tacatggctg cgcattgagt ttttgattca gcaactcacc
     9241 gttaatttac ccatcgttga ccacgctggc gcgctgcatt tcttccgtaa tgtcagtgaa
     9301 ttactggatg ttttcgagcg cggcgaagtc cgcactgagc tgttgaaaga acttgaccgg
     9361 cagcaacgta aactccagac ctggattggc gtgcctggcg tggaccagag ccgtattgaa
     9421 gcattaattc agcagttaaa agcggcgggg agcgtattaa tttccgcgcc gcgtatcggg
     9481 caatttctgc gtgaagatcg tttgattgct ctggtgcgtc agcgactgag catcccaggc
     9541 ggctgttgca gctttgattt acctacattg cacatttggc tgcatctacc ccaggcgcag
     9601 cgcgacagcc aggtagaaac ctggattgcc agcctgaacc cgctcaccca ggcacttacc
     9661 atggtgctgg atttaattcg ccagtcggct cccttccgta aacaaaccag cctgaatggt
     9721 ttttatcagg ataacggtgg cgatgccgac ttgctgcgcc tgaatctgtc gctcgattca
     9781 cagctttatc cgcaaatttc cggacataag agccgttttg ccattcgttt tatgccgctg
     9841 gacactgaaa acggacaggt accggaacgt ctggatttcg aactggcctg ttgctaagga
     9901 gtgaaaatgt cagaaactat tacggtgaat tgcccaacct gcgggaaaac ggtggtgtgg
     9961 ggtgaaatca gcccgtttcg gccattttgc tccaaacgtt gtcagctgat cgacctcgga
    10021 gaatgggctg ctgaagaaaa acgaatcccc agcagtggcg atctttccga aagcgatgac
    10081 tggagcgaag agccaaagca gtgacatttg tctgatgccg cacgtaggcc tgataagacg
    10141 cggacagcgt cgcatcaggc atcttgtgca aatgtcggat gcggcgtgaa cgccttatcc
    10201 gacctacaga cgcttaagct tcgctattac cggttcattg gctggcggaa aatcatcggc
    10261 attaagaccg actagcgaca tccactcacc gggttgccct tctttacccc acggctcccc
    10321 ttcccagctt tcgaccagcc agaaccacag agttatatgc ctgtccggga attcatattc
    10381 cagtttttca aatagcgaaa aatgttgtgg ggtaatcccg acttcttcct gaagttcacg
    10441 caccaccgcc tgttccggcg tttcgcccat ttcaatttta ccgccgggaa actccagttt
    10501 attcgccatg tgcgcatctg ctgcgcgacg cgttataaag atttcattgt tctcgttgcg
    10561 aataatacct accgcaattt gcagcttttt cattgtctta aacctataaa aaaggcgcag
    10621 aatcctgcgc cttttacttc aactgttagc ttttattgca ggcgaccatg gcactgcttg
    10681 tattttttac cagaaccgca cgggcaagga tcgttacgtc ctactttgcg ctcaccggtt
    10741 tgcgccgcca gtgcagctgc ggctgcagag tcgtcatcct gatggctaag ctgctgcatt
    10801 tgcgctaaac gctcggcttc catacgacgc tgttgttcca gctcctcaac ctcttcaggc
    10861 atacgtacct ggactttgct cagcgtgctg ataacttcat attttaacga ctccagcatc
    10921 gctgcaaaca tggagaacga ttcacgtttg tattcctgct tcggatcttt ctgtgcatag
    10981 ccacgcaggt ggataccctg acgcagatag tccatcgctg ccaggtgctc tttccacagg
    11041 gagtcaagcg tttgcagcat gacgcctttc tcgaagtgac gcatcatctc agcaccaacc
    11101 acttcttctt tacgctgata cacttcgatg gactgcgcca gaatgcgctc acgcagcgtc
    11161 tcttcatgca gttctggttc tttatccagc cactcggcaa ttggtaaatc gaggtcgaaa
    11221 tcgttcttca gacgttcctg cagccccgga atatcccaca tttcttccag cgactgtggc
    11281 ggaatgtagg catcaatggt ggctttgaac acatcttcac gaatgctgtt gatggtttcg
    11341 ctcacatcgc tgacatccag cagttcgtta cgctgggagt aaatggcgcg acgctgatcg
    11401 ttagccacgt catcatattc cagcagttgc ttacgaatgt cgaagttacg gctttcaact
    11461 ttacgctggg cgttggcaat cgctttagtc acccacgggt gttcaatggc ttcgcctggc
    11521 ttcataccca gtttacgcat catgccggat actcggtcgg aagcaaaaat acgcatcagc
    11581 gcatcttcca tcgacaggta gaaacgggaa gaaccagcat ccccctgacg accagaacga
    11641 ccgcgcaact ggttatcgat acgacgggat tcgtgacgct cggtaccgat gatatgcagg
    11701 ccacctgctt ccagtaccgc atcgtgacgt acctgccagt cggctttaat tttttcaatt
    11761 tgctctgcgg tcggattttc cagcgcggca acttctgcct gccagctacc accgagcaca
    11821 atatctgtac cacgacccgc catattggtc gcgatagtca ccgcagccgg ataacctgcc
    11881 tgagcaacaa tcgccgcttc gttggcgtgg aatttggcgt tcaggacgtt gtgcttaata
    11941 ccggctttgg tcagttcgtt tgacaccagc tccgattttt cgatggagat agtacccacc
    12001 agcaccggct ggcctttcgc agtacgttct ttgatatctt caatgatcgc ctgaattttt
    12061 tccgcttcag tcatgtagac caggtccggc agatctttac gaatcattgg acggttggtc
    12121 ggaacaacga cggtatccag cttgtagatg gagctaaatt cgaaagcttc ggtatcagca
    12181 gtaccggtca tccccgccag tttttcatac agacggaagt agttctggaa ggtgatcgaa
    12241 gccagcgttt ggttttcgtt ctggatctgc acaccttctt tcgcttccac agcctggtgc
    12301 agaccatcgg accagcgacg gccctgcatg gtacgaccgg tgtgttcgtc aacgatgata
    12361 acttcaccat ctttaacgat gtagtcgacg tcgcgggtaa acagcgcatg agcgcgcagc
    12421 gccgccgtta cgtggtgcat cagcatgatg ttggccggag agtacagaga ctccccttca
    12481 tccatgatgc cctctttcac cagcagttct tcaatcagca ccagaccacg ttcggtcagg
    12541 ttcacctggc gagatttttc gtccaccgag aagtggcctt cgccctggaa ggtttcggag
    12601 tcttcttttt cctgacggat caggtgcgga ataattttat tcacgcgttt atacatttcc
    12661 gagctgtctt ctgccgggcc ggaaatgatc agcggtgtac gcgcttcatc gatcaggatg
    12721 gagtccactt cgtccaccag cgcatagtgc agtttacgct gtacacgttc ttcagggctg
    12781 aacgccatat tgtcgcgcag gtagtcaaag ccgtattcgt tgttcgtacc gtaagtgatg
    12841 tcagctgcgt aagcttcgcg ctttgccggt gctggcatgc ccggcaggtt gataccgaca
    12901 gtcaggccaa ggaattcaaa cagcggacgg ttgttttcgg cgtcacgttg cgccaggtag
    12961 tcgttgacgg taactacgtg cacgccttta ccggttagtg cgttcaggta agcaggcagc
    13021 gttgcggtca gggttttacc ttcaccggta cgcatttcgg cgatgcagcg ttcgttaaga
    13081 accataccgc cgagtaactg aacgtcgaag tgacgcatac caaagacgcg cttacttgcc
    13141 tcacgtacca cggcgaaagc ttccgggatc agattttcca gcacttcgcc tttttccaga
    13201 cgtgcacgaa actctgcggt tttccctttc agttcttcgt cggagagttt ttccatctcc
    13261 ggttccatgg cattgatgat gttgaccact ttgcgcatcc ggcgcagggt gcgatcgtta
    13321 cgactaccga aaactttagt taacaatttg attagcataa taaaatctca aacgccccgc
    13381 gttgcggagt taataaaatg aagtaaaggt ttattgttgt taggtgaggc gttgagggcc
    13441 agcacggatg ccttgcgcct ggcttatcca gacgggcgtg ctgaattttg cttgtggggt
    13501 aaaatgcgca taatcaatgc gataaccctt ttcagacggc gtgccttcct gggtcagcag
    13561 cgcgctgagc gtatccagta atgcaagatg ttgcgcctga agaggcaaag attcttcagc
    13621 aacgggcagt gtttgcggtg ccattgcgaa agaaagatga cggattaccg tgcgaatggc
    13681 atgttgatgc cagtaatcaa cggaatagtt cgaattcggg cggcgtgtgt tcgcttccag
    13741 caaggccaat tgaccaaagt taactttggc tgaaggctcg tggttgcggg ttgtcgcttt
    13801 tgcgggcgcg tttggttcgg cggcgttgct gagcgcaggc aaacctaaac tcgccgcaac
    13861 catccctaat aagagatgcg gccagaagta gcgtttacca aactgtcgcc agcgcgtcag
    13921 tattccactc acgttattgc catcccgatc gtattcaaac gtatttagcg cacaaatctt
    13981 atcattaaag cctgcagtcc acagcacgaa tgaagataag ttgtgcggaa aagtgcttaa
    14041 gaaaacagcg ttcgcaccgt tttttatagc tcttataaaa ttcaaaaaaa aacgactggt
    14101 tcacctggcc ggagagagtg ccagatttgc cagtcgaatt ttatacgaca gtataaatgt
    14161 cgttatgcca gtacagctga aggcgctttg aaggccaacg gcagttctgc gtcgtcctgg
    14221 aaggtcacat attcccaggc ttcctgtttc gccaggacag cctgcagcag tttgttattc
    14281 agtgcatgac cggatttata agcggtaaat gcaccaataa tattgtgacc acacatgaac
    14341 aagtcaccga tcgcatcgag cattttgtga cgcacaaatt cgtcttcaaa acgcaggccg
    14401 tcttcgttca gtacgcgata atcgtcaaca acgatggcac aatcgaagct gccgcccagg
    14461 cacaaaccac gggactgcag atattcgata tcacgcatga aaccgaacgt acgcgcacgg
    14521 ctgatctggc gcataaacgc atcagcggag aagttcatcg catagcgctg gttgctggaa
    14581 tcaatagccg gatggttaaa atcgatggtg aaatccagcg aaaaaccatt gtacggctta
    14641 aattcagccc acttatcgcc atcttcgaca cgaacagtct ctttgatgcg aacaaatttt
    14701 ttggcgcagt tcaactcgtc gataccggcg tcaagcagca ggtatacaaa cggagcggcg
    14761 ctgccgtcca tgatcgggat ttccggcgcg ttaacttcga taacaatgtt atcgatgccc
    14821 aagcccgcga gagcagcatt gaggtgctct acggttgaaa tccgtacatc atgctcgttg
    14881 accagacacg tacagagcat ggtatcacgc acagatttgg catcggccgg gaaatctacc
    14941 ggtggattca agtcggtgcg acgatagatg accccggtgt tggccggcgc agggcgtaac
    15001 gtcagggtga ctttcttgcc ggtatgtaaa ccgacacccg tcgcctgaac gatacgttta
    15061 agtgtccttt gtttgatcat cgtattatct cgccaaatta cctatccaac cgaagtgtac
    15121 tatacattcg gcgggccagt ttagcacaaa gagcctcgaa acccaaattc cagtcaattc
    15181 ttaatcagct tgcttacgca ggaatgctgg gatatccaga taatccggct ctttcgcagt
    15241 ttgcggcgca ttgtcattca cgactttagc aaccggcttc tgctcctggg tcagcggagc
    15301 catcccatgc tgctggtagc gatccatcac tggctgctga acctgcttat tggtcaccag
    15361 agtgatttca ggacgtttgt ccatgccgat acctgtcgca acaacggtta cgcgcagctc
    15421 gtcattcata tccgggtcaa gagaagtacc gataaccaca gtcgcgttgt cggaagcaaa
    15481 tgcacggatg gtgttaccta ccgtttcgaa ctcatccaga cgcaggtcga agcccgccgt
    15541 gatgttaacc agcacgccgc gcgcgccaga caggtcgata tcttccagca gcggagaaga
    15601 gatagccatt tcagcagctt cttccgcacg gtcttcaccg ctcgccacgc cagaacccat
    15661 cattgcgtag cccatctcag acattacggt gcgtacgtct gcaaagtcca cgttcatcaa
    15721 acccggacga gtaatcagtt cagcgatacc ttgcacagcg cctttcagta catcgttcgc
    15781 tgcgccaaac gcatccagca gggagatacc gcggcccaga actttcagca gtttgtcgtt
    15841 cgggatagtg atcagagagt ccacatgctt ggacagttca gtgatcccct gctccgcgaa
    15901 tgccatacgc ttcttgcctt caaagttgaa aggcttagtg acgacagcaa cggtcaggat
    15961 acccaaatct tttgccactt cagcgacgac tggtgctgca cctgtaccgg taccaccacc
    16021 catacccgca gcaataaaga ccatgtctgc accttccagc gccgcacgca atgcatcgcg
    16081 atcctcatca gccgcattgc ggccaacttc tggattagcg ccagcgccca gtcctttggt
    16141 gataccgcta ccgatttgaa tcgtctgtcc aaccgctgtt ttacgcagcg cttgtgcatc
    16201 ggtatttacc gcgaagaatt caacaccttc aatgcgctcg cgcaccatgt gttcaacagc
    16261 attaccgccg ccgccgccga cgccgatgac tttaatcacc gcgtcattgg taagttccat
    16321 tggttcaaac atagtttctc tccgatttgt gcctgtcgcc tgaggccgta atcatcgtcg
    16381 gcctcataaa aattaaaact cttttcgcag ccaactattg agtcgcttga tccacgagcc
    16441 aactgatgct gtaacacgtt tttctacttc agcttcaccg ttaagatgtg actctttccc
    16501 atagtgaagc aatcccaccg ccgtcgaata atacggctcc tgagcataat ccgttaaacc
    16561 ggtaatgttc agcggcgcgc cgatacgcac ttgcgtatga aacacgcgct gagcacaggc
    16621 tgcaagacct tcgatctgcg ctgcgccacc ggttaataca atgcctgccg ccaggtgatg
    16681 tttaacccct tgttggcgaa gcttttcctg caactgcaat atctcttcgt tgaccaggtt
    16741 gagcagctcg gtatagcgcg gctcgatcac ctctgccagg gtctgacgtt gcagactccg
    16801 tggcggacga ccgcctacgc tcggcacttc cacgctctca tcttttccaa cgatggaacc
    16861 cagcgcacaa ccgtggcgaa ctttaatcgc ttcggcgtcg cttggcggcg tgccaaaggc
    16921 gtaagcgata tcactggtca cgacattgcc agcataagga attaccttag tgtggcgcaa
    16981 tgccccaccg gtataaacgg cgatatccat tgtaccacca ccgatatcga cgacgcagac
    17041 acccagttca cgttcatctt ccgtcaatac cgaataactt gatgccagtc cggcaaatat
    17101 cagttggtca actttcagcc cacaacgttc aaccgctttg acgatgtttt tcgccatatc
    17161 gttgtgacat gtgatcaggt gcacttttgc ctgcatccgc acgcccgaaa gtcctaccgg
    17221 attcttgatc ccttcctgat agtcaatcgc atactcttgc gggatcacat gcagcacacg
    17281 atgttcatcg cgcacacgca ccgatttcgc ggtatggacg acgttttcca catcttcttg
    17341 cgtcacttct tcttcagaaa taggcaccat accaatttca ttctggcagc tgatgtgctt
    17401 accagaaagc gccagatata ccgaagagat ctgacaatct gccatcaatt ctgcctggtc
    17461 aatggcgcgt tgtacgcact tgaccacgga ttcgaggtcg ttcaccccgc ctttatccat
    17521 accacgtgac gggcagctgc ccacgccaat gatattgacc ataccgtcgg gcagaacttc
    17581 ccctactaaa gcggcaacct tcgcggtacc aatctccagt cctactacca gttttctgtc
    17641 cgtcgccttg atcattgttg ttctgcctgt gcctgatttt gttgctgagt agattcctct
    17701 ggcggcaagg gcgcccagcc tactgccgct ccagagtcat aacgcaaatc aacgtagcta
    17761 atccgtttgc catcggtttg cgcctgctgc tgtaaaaccg gataaagttc tacaaagcga
    17821 gccaaacgtt tcatcgtatc gccccggcca agattgagct taatatcgtt attcagcgtc
    17881 aactgccagg aacgccgcgc ggtcatcgcc gcttccttca gagtaaatct gtcctttgcc
    17941 agcatctgcc ccatttcgcg atagccctgc aacacttcat tggcgctgcc ttccgggcca
    18001 tacagcattg gaagcacctg cttgctggtg cgatctggcg gcacgctgaa ggtgtttcct
    18061 tccgcgtcta ccatgtgttg atcattccac cgcgcaatcg gcacatattc aaccagatga
    18121 atcttcaatt catcaggcca ctgctttctg acgctcacct gcttaatcca cggcaggcgt
    18181 tgttctattt gcgtctggat gatgttgaca tcctgggtca taaaggtacc cggctcaccc
    18241 aatgccagga tcgactgccg gatatcgtca ttacgcgtgt aatggcgttc accggtcaac
    18301 accagctttg agagcggcag gcgttgcgca tcttccatcc agcccaacac gacccagccg
    18361 ctcaccaaca ctgtcgttaa aacggtcagc aggaaaagga tccccgccag acgcgttcca
    18421 ttattgcggc gagaagaaac ctcttcttcg ctatttcgcg tgttcagagc agcctgcgac
    18481 atattagtcc gccagttcca gaattcgtac taccaactgc gagaagctca tacctgcctg
    18541 acgtgccgcc atcggcacca ggctgtggct ggtcataccc ggtgaggtat tggcttccag
    18601 cagataaaac tgtccatcgc tgtccagcat aacgtcaata cgtccccatc ctttgcaacc
    18661 taacgtcgtc catgctttca gcactaatgc ctgcaaattg gcctcttgtg acgcttccag
    18721 acctgcgggg cagaaatact gtgtctcatc agagagatac ttcgcctcat aatcatagaa
    18781 ggttccggac ggttgaatac gtattgacgg taaaatttct tcaccgagta tcgcaaccgt
    18841 gaactccggc ccacttagcc atttttcaat caatacttct tcatcgtgct gaaatgccaa
    18901 tcttaatgca tcttgtagag cattttctgc tactactttt gacattccca cactggaacc
    18961 ttcgcggctc ggcttaacga taaccggcaa acccagagca gaaatttctg ctaactgctt
    19021 atcgctcagg cctttttcaa actctgcgcg ggttaacgct acccacggcg cgaccggtaa
    19081 accggcacct tgccacagca gtttgctgcg tagtttatcc attgaaagcg cagatgccat
    19141 cactccgctg ccggtataag gcaagcccat cagctcgagc atgccctgca gcgtaccatc
    19201 ttcaccgccg cgaccgtgta gcgcgataaa cactttctga aaacccatcg acttcagttg
    19261 cgtcacgtcg acttctttcg ggtcgacagg atacgcatca ataccgcctt cacgcagccc
    19321 ggctaacacc gctgcgccag aattcagaga aacttcccgc tcagcggaag tcccgcccaa
    19381 caggaccgcg attttatcag tcatgttgtt cttcctccgg agtttgcggc ttcagtttga
    19441 tttcagctaa agaacgggca atttttccga tattaccagc cccctgaacg agaatcaggt
    19501 cgttaccggt taataccggt gccagcatct cggctacctg cgcagggtcc ggcaccagaa
    19561 tgggatcaat tttcccacgt ccacgaattg tgcgacacag cgaacggctg tccgctcccg
    19621 gaattggcgc ttcgccagcc ggatacactt ccagcatcaa cagggtatca acctgcgtca
    19681 gcacattggc gaaatcatca tacaggtcgc gcgtacgggt aaaacggtgc ggctgaaaca
    19741 gcattaccag gtttttatcc ggccagcctg cgcgcgccgc tttaatggtg gcgtcaactt
    19801 ccgtcgggtg gtggccgtag tcatcgacca gcattgccgt accgctttta ccattcactg
    19861 gctccagcgg gaattcaccg aggaaatcaa aacggcgccc agtcccctgg aagctctcca
    19921 gcgcacgtaa aatagcctcg tcatcaattc cctcttccgt agcaaccgca accgcagctg
    19981 cggcgttcag cgcgttatga cgacctggcg cattcagggt gacgcgcatc ggctctttgt
    20041 cctggcgcag cagcgtaaag tgcccctgcg ggccaatctg ctgataatct tctacacgca
    20101 cgtcggcatc ttcgctgaag ccgtaagtcg tggtctgacg tcccactcgc ggtaacaatt
    20161 cgcggatcac cggatcatca acacacatca ccgcacgacc gtaaaacggc aggttgtgca
    20221 gaaaattaat aaaagtctgt tttaaattct caaagtcgcc ctggtaggta tccatgtggt
    20281 cggcttcgat attggtgaca atcgccacca tcggttgcag atgcaggaac gatgcatcac
    20341 tctcatctgc ttcggcaatc aggtaccgac catgccccaa acgcgcatga acccccgccg
    20401 cttttaccag cccgccgtta acgaaggttg ggtcgagccc cgcttctgcg tagatgctgg
    20461 aaaccatcgc ggtggttgtc gttttgccgt gcgttcctgc aatggcgatg ccatgacgaa
    20521 aacgcattaa ctcagccagc atttcggcac gacggatcac cggaatacgc gcttcatgag
    20581 ctgcgacaat ttccgggtta tcggcagaaa tggcgctgga aacaacgacc acgctggcat
    20641 cacgtacgtt ttccgggcga tggttgaaat aaatcgtcgc tcccagattc attaactgct
    20701 gcgtgaccgg atttggcgct aaatcggaac cactgatctg ataaccttca ttggccagaa
    20761 cttcggcaat accgcccata ccggcaccac cgatgccgac aaaatgtatg tgccgaacgc
    20821 gacgcatttc gggcacgatg gaacgcagtt ttgccaattg ttgtgtattc attctttacg
    20881 ccattaactt cttaaattca tacgatgcaa aaggcatcgc tacaattacg cccgggcagc
    20941 ccggctcact tcatttgcca ctcgctcggt ggcatccgga atggatgcag cgcgggcgcg
    21001 ttctgccatg gttaataagg tttctcgcga ccacccggcc agggtgttgg cgacagcatc
    21061 cacgctaagc tgtggctgct cgataatttt ggctgcgccc gctttttcca gcggtagcgc
    21121 attccagtat tgctggcggt ctttatgttg aaacggcaca aacaacgccg gtagtcctgc
    21181 cgcggcgatt tcactcaccg ttaaagcacc ggagcggcaa acgacgacat ccgcccacgc
    21241 atacgccgcc gccatatcat caataaattc cgtcacttta tgctgcggtt gccccgcttc
    21301 ggcatacgcc tgttcaacgg attgttgcga acctttaccg ctctgatgcc agatagtgac
    21361 tgaatcaccc agtttcgcag caacctgcgg cattgtctgg ttaagaatgc gtgcgccctg
    21421 ggaaccaccc actaccagca cacgaaccgg accttcacgt ccagccaaac gttgctgcgg
    21481 caacggcagc gccagcacat cggtacgcac cgggttaccc accacttccg cattagggaa
    21541 agcgcctgga aacgcctgca tcactttggt ggcaatcttc gccagccatt tattggttaa
    21601 gcccgcaata ccgttttgtt catgaagtac aaccggaatg cctaacgacc acgcggccag
    21661 accacctgga cctgatacat agccgcccat accgagtacc acgtcaggtt tgtacgcttt
    21721 cataatcgcc cgcgcctgac gccaggcgtt gaagatacgc agcggcgcag ctatcagtgc
    21781 ttttatacct tttccacgca gaccagagat acgaatgaaa tcaatttcga tgccatgttt
    21841 tggcactaag tccgcttcca tacggtcggc agtccccagc cagcgaactt gccaaccctg
    21901 agccattaga tggtgcgcaa ccgccagtcc cgggaataca tgtccaccgg ttccgcctgc
    21961 catcaccatt aatcgctttc cttgaccact catcgtgaac ctcgtacaaa cgcctgcgct
    22021 ttctccagac gcgtttcata atcaatacgc aacagcatca tgatggctgt cgacataatc
    22081 agtaagctcg aaccaccgta actgatcagc ggcaatgtca gacctttggt cggtaacatc
    22141 cccgccgccg cgcctacgtt aaccagcgcc tggaagctaa accagatgcc aatagaacag
    22201 gcgagaaaac cggaaaaacg gtggtcaatt tctaacgctt tgcggccaat cgacatcgcg
    22261 cgaaaagcga cgaagaatac cattaaaagt gccagcacca caccgacata ccccagttct
    22321 tcgccgataa tggcgaaaat aaagtcagtg tgcgcttccg gcagatactc cagtttttgt
    22381 accgagttac ctaaaccttg tccccaaagt tcgccgcgac caaacgccat cagcgattgc
    22441 gttaactgat agccgctgcc aaagggatct tcccacgggt tccagaatgc ggtaacacgg
    22501 cggatacggt acggttcggc gagtatcagc aacacaaccg ctgaaatgcc cataccgata
    22561 atggcaatga actgccacaa tttcgctccc gccaggaaca acatcgccag cgtagtcaca
    22621 aacaacacca ccaccgtacc aaggtctggc tgtgccagca gtaacactgc caacaccaga
    22681 atcacgccca tcggtttcag gaagccgcgc aggttattac gtacttcgtc gcctttacgc
    22741 accagatagt tggcgatata acaaaacagc gacagttttg tcagctccgc aggctggata
    22801 cgcagcaaac cgagatcgat ccaacgcgat gcccctttaa ccgagctacc cactaccagc
    22861 acgatcatca gcaggatgat agatccgagc agcatcgtgg cactgtagcg ttgccagaac
    22921 tccatcggca gacgcagcgt aatgatcgcc agaatgaatg ccaggatcag atagacgcca
    22981 tcacgcttcg cgaagaagaa cggatcgttg gttaagcgtt gccctatggg cattgacgcc
    23041 gaggtcacca tgataaagcc aatcgccgca aggccgaagg tcagccacag taaggtgcga
    23101 tcgtacatga tcaggctgtc ggtatctttt tcccgcgagc ccatcaccca gccttttagc
    23161 gccgtggaga tccagaccag gatactgaat cctggcaggc gcggcatttt caggcgaggg
    23221 agagataaac gcatcaacct aactccttcg ccagacgggc aaactcattg cctcgttgtt
    23281 caaagttctt gaactgatca aggctggcac aggccgggga gagcagaacc atatcgcccg
    23341 gctgaacacg cggagccagc aagcgcatcg cctgttccat agtttcggtt tgttctgcca
    23401 cttccgggcg tagcgccgcc agctgcgcac cgtcacgacc aaaacagtac aaacgcacgt
    23461 tgtcgccatt cagatagcgc gccagtggac tgaagtccgc cgatttacca tcgccgccca
    23521 gcaacaaatg cagcgtgccg tctacctgca agccattcaa cgccgcttcc gtactgccga
    23581 cgttagtggc tttcgaatcg ttaatccagc gtacgccatt gtgctccagc accacttcaa
    23641 agcgatgcgg cagaccggtg aaggtggtta acgctttcag gctgctggcg cgcggcaaac
    23701 cagctgcgtc tgccagtgcc agtgctgcca gcgcattggt gtagttatgc tgcccggaaa
    23761 gtttcatctc tttcacgttc agcactttct cgcctttcac tcgcagccag gtttctccct
    23821 gctgatgatt caggtgatag tcacccatgt tgacgccaaa gctgacgcag cgttcatcag
    23881 caccgcgaat cggcattgtt aaggcatcat cagcattgac gacacaaact ttcgcatttt
    23941 cgtaaatacg caattttgcc gcacggtatt gctgcaaacc aaacggatag cggtccatat
    24001 gatcttcagt cacgttcaga atggtcgccg ccaccgcctg taagctggaa gtggtttcca
    24061 gctggaagct cgacagttcc agcacgtaca gttcgcactc agcatcaagc agcatcaacg
    24121 ctggcaggcc aatattgcca cccacaccaa cgttaacccc cgccgctttc gccatttcac
    24181 ccactagcgt ggtgaccgtg cttttgccgt tagaaccggt aatcgccaca atcggtgctt
    24241 gtgcttcgcg gcagaacagc tcgatatcgc caacgatttc gattccggca tcagcggcag
    24301 cgcttaagga tggatgcgcc agtgcaatac cgggactggc gacaatcaga tctgccgcca
    24361 tcagccattc atcattcaga ctgcccgtgt ggcgttctac ggcttcgggt aatttatcca
    24421 ggccaggcgg tgtcatacgc gtatccataa cgcgcggcgt cagaccgcga gcgaggaaaa
    24481 agtccacgca ggaaagccca gtgaggccca ggccgataat gacgacattt ttaccctgat
    24541 aatcagccat gattaacgta ccttcagcgt tgccagacca atcagaacca gcatcagcga
    24601 aataatccag aaacgcacaa tgacgcgcgg ttccggccag cctttcagtt catagtggtg
    24661 atgaatcggt gccatgcgga aaatacgttg tccgcgcagt ttaaaggagc cgacctgcag
    24721 gatgacagaa agcgtttcta ccacgaacac gccccccata atcaccagca ggaattcctg
    24781 acgtagcagt acggcgataa tgcctaacgc accacctaac gccagcgaac ctacatcgcc
    24841 cataaagacc tgcgccggat aggtgttaaa ccacaggaag cccagtcctg ccccgactat
    24901 cgcggtacag acaataacca gttcccctgc gtgtcgcaga tacggtatat gcaagtagct
    24961 ggcaaagttc atattgccgg tcgcccacgc caccagcgca aaaccaccgg cgacaaatac
    25021 ggtcggcata attgccaggc cgtcgagacc atcggtcagg tttaccgcgt tgccagtacc
    25081 cacaatgacg aagtaagcca gcagaatgta gaacagcccc agctgcggca tcacatcttt
    25141 aaagaatggg accaccagct gcgttgcggg cgtgtctttg ccggcaaggt acagggcgaa
    25201 ggcgacaccc agcgcaatga ccgacatcca gaaatacttc caacgagcga tcaacccttt
    25261 ggtgtcttta cgcaccactt tgcgataatc atcaacaaag ccaataacac cgtaacctac
    25321 cagcaccacc aacacgcacc agacgtacgg attggacggg taagcccaca gcagtacgga
    25381 gatcacaatc gccgtcagga tcataatccc gcccatggtc ggcgtaccgc gcttgctgaa
    25441 gtgtgattca ggaccgtcgt tacgcaccac ctgaccaaag gaaagttttt gcaaatgagc
    25501 aatcatacgc gggcccatcc acaatgagat gaacagcgcg gtcagcaggc tgacgatggc
    25561 gcgaaacgtc agataggaaa agacgttaaa gccggaataa tatttgacca aatgttcggc
    25621 cagccaaact aacatgtccc attctcctgt aaagcgcgta ctacctcttc catggcggca
    25681 ctacgtgaac ccttaactaa aatcgtaatt acctgttgct cagcaatcag tgatttaaga
    25741 cgcgtaatta acgcagtttt atcagcaaaa tgttcgccaa cgccgctggc ggtgctgata
    25801 gcatggcttt gtttacccac gcttaacacg cggtcaatac cagcagcttt tgccgcctcg
    25861 cccacctgta catggcaggc ttcgctttca gcgcccagtt ccgccatatc gcccaccacc
    25921 agcacgcggt agcccggcat ttcagccagt acctgaacag cggcggtcat tgaaccgaca
    25981 ttggcgttgt aggagtcgtc gagcagcaac tggttttctg ccagttggat ggggaacaga
    26041 cggcctggaa cagctttcag atttgccagc cccgctttga tagcatcaag cgttgcgccc
    26101 acggacatgg agagcgcagc ggctgccagc gcattcgcaa tattgtgacg ccccggcaac
    26161 ggcagcagaa catcgacgct accggttggg gtttgtaggg taaattccgt accgtgcgag
    26221 gtcacatgga tattggtggc ggtgaaatcg ctgttggcgg cattgggtga gaaacgccac
    26281 actttgcgtg agccaattac gctctgccag ttcagccagt cgttgttgtc ggcgttcata
    26341 atggcgatac cgttttccgg caggccgcta aagatttcac ctttcgcttt cgcgacaccc
    26401 gcaagcgagc caaaaccttc cagatgcgcc gctgccaggt tgttgaccag cgcagcttcc
    26461 gggcgagtca gactcacagt ccaggctatt tcgccctgat ggttcgcgcc aagttcaata
    26521 actgcgtaat cgtattccgg cgttaagcgc aacagcgtca tcggtacacc gatgtcgttg
    26581 ttgagattgc ctgccgtata aagcgtgttg ccgcactggc ttaaaatcgc cgccgtcatc
    26641 tctttaacgg aggttttgcc ggaggacccc gtcagagcaa ccacgcgcgc cggaacttgc
    26701 tggcgaaccc atgcagccag ttcaccaaac gccagacgcg tatccttgac gattaactgc
    26761 ggcaggtcga tgtccagcgg acggctaacc agtagtgcgc ctgcgccgcc agctttcgcc
    26821 tggtcggcaa aatcgtgggc atcaaaacgt tcgcctttca gggcaacaaa caggcagccc
    26881 ggcgtcagtt ttcgggtatc agtggttaca gcatcaaggg tgatatctgc accttgcagt
    26941 tcaccgttga gaatgtcggt aagttggcta agggttacgc taatcatgca atcaccccca
    27001 gcagacgcgc caccgtgacg cgatcggagt agtccagacg ctgattgcca acaatctggt
    27061 aatcttcatg gcctttgccc gcgaccagta ccacatcatt ctctttagcc tgcataacgg
    27121 cgcaagtcac cgcttcagca cggccttcca tcactttggc atgtccggca tctaacattc
    27181 ccgccagaat atcgttgatg atggcacgcg gttcttcggt acgcgggtta tcgtccgtca
    27241 ccaccgccac gtcagcaaac tcttcggcaa ttgcgcccat cagtggacgc ttacctttat
    27301 cgcgatcgcc accacagcca aagacgcacc acagcttgcc cgcacagtgc aggcgcgccg
    27361 cctgtaaggc tttttccagt gcatccggcg tatgcgcgta atccaccacc accgtcggtt
    27421 tgcctggcgc agtgaacact tccatacgtc cgcaaaccgg ttgcagacgc gcggcggttt
    27481 tcagcagatc agccagtgga tagccgagtg ccagcagtgt cgccagcgcg agcagcaggt
    27541 tgctgacgtt aaaagcgccc atcagatggc tttcaatttc gccatcgccc caacttgagc
    27601 taaagcgaat cgtcgcaccg ctgtcgtgat agttcacgtc gatcgctttt aaccagcgtc
    27661 cgtgacagtt cggattgata tgatcttcca ttgataccgc aaccgcgtcc ggcagttttg
    27721 ccagccagcg gcggcccact tcatcgtcgg cgttaataat cgcctgaccg caatgatgtt
    27781 cagaataaag cagccatttc gcagcttcgt agtgttccat atcaccatga taatcaaggt
    27841 gatcgcggct taagttggta aagaccgacg ccgcaaattt caatgccgcc acacggtgct
    27901 gtaccagccc gtgggaggaa acttccattg cgcaaaacgt cgcgccctgc tccaccagcc
    27961 ccgccagctc atgctgaaca tcgactgcgg aaccggtagt attttctgtc gggatcactt
    28021 tcccaagcag accgttacca acggtgccca ttaccgcgct ggtttcgcca agcagttggc
    28081 tccactgcgc cagcagctgg gtagtcgtgg ttttgccgtt ggtgcccgtt acgcctacga
    28141 gacgtaaatt gtcagagggt tcatggtaaa agcggcccgc cagtgcagat aaacgctcgt
    28201 tgagctggct gagatagatg accggtacgc cgtgcatttc acggatttca ccatcggtcg
    28261 cctcatcttt cgcctctgca ataatggcag ccacaccttg cgctatcgcc tgcgggatat
    28321 atcgacgccc gtccgcctga tgacctacta cagctacaaa gagatcgccc gccgcagcca
    28381 cacggctgtc gagtgtcatc tctcgcagtg ctcgcgaagg tgcgtctggc acccacggag
    28441 caagaaggtc gcgcaaatta cgatctgcca cctgtcccct cgccttgatt aatcacaaat
    28501 tcatttttat cgcccgttgt cagcgcatcc ggctcgatgt tcatggtacg caatacgccg
    28561 cccatgatgg caccaaagac cggcgcggaa acggcgccgc cgtagtattt acccgcctgc
    28621 ggatcgttga taacaacaac cagcgcgaag cgcggctgac tcgcaggcgc aacgcctgcg
    28681 gtataagcaa tatatttatt gatgtagcga ccgtccggcc cgaccttttt cgcggtaccg
    28741 gttttaatgg cgatacgata gcctttaatc gccgctttca cgccgccgcc gcctggtagc
    28801 gccacgcttt ccatcatatg caccacggtg cgaacaatgg attccgggaa gacacgttca
    28861 ccgggaaccg gggggtcaac tttggtaatc gacagtgggc gataaatgcc gtagctgccg
    28921 atagttgcgt agactcgcgc taactgtaac ggtgttacca ttagcccgta gccgaaagag
    28981 aaggtggccc tctctatgtc agaccaccgt tgtttttgag gatataagcc actgcgttct
    29041 ccgaccaacc ccaaattggt cgcttttccc agtccaaaac gtgagtaagt atctactaac
    29101 gctgaggacg gcatcgctaa cgccagcttg gaaacaccga cgttactcga cttctgtaat
    29161 accccggtca gggttaattc gctgtagcgt gccacgtctt tgatttcgtg gccgttaatt
    29221 cgataaggaa tggtattgag taccgagttt tcccgcacca cgccacgttg caacgcggtc
    29281 attaccacca tcggtttaac cgttgagccc ggttcaaaca cgtcggtgat ggtacggtta
    29341 cgcatcgcct ctttcggcgt gccgctcaga ttgttagggt tgtatgacgg gctgttagcc
    29401 atcgccagca cttcaccggt gttgacatcc accagcacgg cgctaccgga ttcagccttg
    29461 ttaaaggcca ccgcgttgtt cagttcgcga taaaccagcg cctgcaagcg ttcatcaata
    29521 ctcaacgcca ggttgtgcgc cgcctggctg tcagtagaag aaatatcttc aattacgcga
    29581 ccatagcggt ctttacgcac aatgcgctca cccggctgcc cggtaagcca tttatcgaaa
    29641 ctcttctcaa cgccctcaat cccttgacta tcgacgttag taaagccgat gaggtgagca
    29701 gtcacttcgc cggacggata gtaacggcga gactcttcac gcagatgaat ccccggcagt
    29761 ttcagttttt tgatgtagtc cgccatgtca gggttcacct gacgcgccag ataaataaag
    29821 cgccctttcg ggttggcgtt aatgcgggct gaaagctgat ccagcggaat attgagcgcg
    29881 ttagccagcg ccttccagcg gtcaccgacg ctgataccgc cagcgtcatg cacttctttc
    29941 gggtcagccc aaatcgcttt taccggcacg ctcaccgcta acgggcgacc agaacggtca
    30001 gtaatcatgc cgcgggaggt ggaaacttgc tgaacgcgaa gagaacgcat gtcgccctct
    30061 ttcaccagca tatccgggga gataacttgt aaccacgcta cgcgtccgag cagaaaagcc
    30121 agcgccagga gaatacagcc gcataacaac gcaaaacgcc aactgataaa gttggcatgt
    30181 tcttcctgac gttttggttt ctgcgttttc gccgctgctt tcatgcgtcg cgtttatcct
    30241 tatttttgca ctacgatatt ttcttgtgac ggatcaacat gctgcatttg cagcttttcc
    30301 gtggcgatcc tttccacccg gctatggtcg ccgagcgcat tctcttcaag gatcaggttg
    30361 cgccattcaa tgtctaaagc atctcgctcc agcaccagtt gttcgcgctg agcggtcagt
    30421 aaacgggtat ggtgcgccgt ggttaccaca gtcaccgccg tcaaaataat gcaaatgaac
    30481 aggcagagtg gcagcttccc aaatcgcaaa agatcgtcac cgataacacc aggcaatgca
    30541 tggcgctcgt ggcttcccat cgatccttta actttgctta gagcttctgt cactctgctg
    30601 atcatgcatt cgtcctctct gcaatacgca gaactgaact acgggcacga gggttctcag
    30661 ccacctcttc ttcgcccggc attaacttgc ctagtgctcg cagctgacgg ccacccagtt
    30721 ttttgagctg ctcttcagtt atcggtaacc ctgccggaac ttgcggaccg cggctgtttt
    30781 cacgcataaa acgtttcaca atacggtctt ccagcgagtg gaagctgatg atcgaaagcc
    30841 gcccacccgg ggccagcacg ttgagcgagc tttttagcgc ctgctctatc tcctccagtt
    30901 cactgtttac ccaaatgcgc accgcctgga aggtacgggt cgcgggatgt ttaaacttat
    30961 ctttcaccgg cgttgcagca gccacgactt ccgccagttc tttggtgcgg gtcatcggct
    31021 gttcgcggtt acgctcgaca atggcgcggg caatgcgttt ggcaaaacgc tcttcaccat
    31081 aggttttcaa tacccaggcg atatcggctt cttctgcggt ttgtagccat tcagcggctg
    31141 actgcccacg ggttgggtcc atacgcatgt ccagcggacc atcgcgcata aaggaaaagc
    31201 cgcgctcagc atcatcaagt tgcggtgaag agacgccaag atcgaggaga atgccgtcga
    31261 tcttgccgat aagatcgcgc tcggcaacgt attcgcccag cgcggagaaa ggtccgtgga
    31321 tgatggagaa gcgcggatca tcaatagtct tcgcaacggc gatagcctgc gggtcgcgat
    31381 cgatcgccag caaacgcccc tcttcgccaa gctgcgagag gatcagacgt gagtgaccac
    31441 cgcgaccaaa agtcccatca atgtagatgc catcaggacg gatattgagg ccattaacgg
    31501 cttcatccag cagcaccgta gtatgtttat agttttccat cattttatag agacaagtcc
    31561 tgcagtcgct ccgataagtc tccggtagcc aactgctctg cgtcgatatc ttccttgacc
    31621 tgttgatgcc aggttgtttc atcccacagc tcaaacttgt tgaactgtcc aaccagcatc
    31681 acttcttttg tcagcccggc atgttgccgc agtactggcg cgattaacaa tcgacctgcg
    31741 ccatccatct gacattcgct ggcatgacct aacagtaggc gctgcacacg gcgctcaacc
    31801 gggttcatgc tcgacagacg cgataatttt tgctcgataa tttcccattc aggcaggggg
    31861 taaagcagca ggcacgggtg atgaatgtca atggtgcaaa ccatttgacc ggcagcgttc
    31921 tcaagcagct gttcccggta acgggtaggc actgataagc gccctttgct gtcgagattg
    31981 actaacgttg ctccccggaa catgccagcc tcacccctta ttcccacttt gccccacaat
    32041 ttcccactga aaggagttta cggagcggag gaaaagcttg tcaagccagt cacaaggcat
    32101 accgaggtaa aaaacccgat gtttacggct aatatcagcg ttgtttattt tacgtccaac
    32161 gtgcgcagca aattaacgtt atgaatagct gtaagaaaaa atccctcatc gtcatcaccg
    32221 ttttaaaatg actcactatt ttccacagca aatataaagt gtcagtttgc gacgcgagcg
    32281 gcattttagg acatatcttc cccggttaac agtccctgtt gcgtctgtgt ggcgcttgat
    32341 gccagcgggt ttgcgcaaaa gcaaagaaaa gtgcttgtta aatcggcaat tcatctctgc
    32401 atgtaacaaa ataatgcaaa aacgcgctgt cgatatcact taattattgt gaatttcagc
    32461 tggtgattta attaacgggc gggtttaaaa gaacttatca ataatagtca ggaatagtct
    32521 tatttacttt aaggatattg atgtccattc ccgtactcta cgcgccagag ggaaattcac
    32581 ctggcgcgta tttttgttcg cggcttagct acggctgagc acaccgcgac gatagagatt
    32641 acgtttaatg cgcgttaaac caggttttgg cttacgcggt tcgtccaggc ttgccaggac
    32701 aatctccagc acacgctctg cgacatcgcg gtgacgttga gccactgcca gcaccgggca
    32761 ctgtaagaag tcgagcagtt cgttatcgcc aaaggtggca attgccaggt cagaaggcag
    32821 tttaccatcg cgacgtagcg ttacatccat caccccttgc aacaacgcaa acgacgttgt
    32881 gaacagcgcc tgcggcatcg gatgcgtttc cagccatttt tcgaataact gggcagccgc
    32941 ctcccgctca tagctgttgg catacaggaa atgcacttcg cgcggatcat ctttccaggc
    33001 agtacggaaa ccttgttcac gcaggaagct gacagaaagc tccggcagcg cgccaagata
    33061 aagcaccgtc tcggcgggaa acttacgtaa ctcttccgcc agcatttcgg catcatcctg
    33121 atcggcacca accacgctgg tgaagtgttc acgatcgagg gcgcggtcca gcgcgacaat
    33181 cgggaacggg tcgttagccc agcgttgata aaaaggatgc tcaggaggca acgacgtcga
    33241 aacaataatg gcatcgacct gacgctgtaa aaggtgctca atacagcgca tttcgttgtc
    33301 tggctgatct tctgagcagg caattagcag ttgataaccc cgttgccgcg cctggcgttc
    33361 aagatagtta gcgatgcggg tatagctggt gttctccaga tcggggatca caagaccaat
    33421 agaacgtgtg cgtccagcac gaagcccagc tgccacggcg ttcgggtggt aattgtgctc
    33481 acgcaccaca gccatgactt tttcaacggt tttgtcgctc acacggtatt gcttcgcttt
    33541 gccgttaata acatagcttg cagtggtccg cgacactccc gccagccgag cgatttcatc
    33601 cagtttcaca attgcccctt gcgtaaaatg taaaaaccat agccattgta ctggtatggg
    33661 ttaaattcat taacatctaa gcgcagaaaa ttaactgcgg caactgcttt tattccaggt
    33721 tcccactgat ttcgcaaaaa aagcccaacg tgacatgttg ggctgcaaat tgcgcactga
    33781 gatcattctc aacgcattat tttatcgccg cgcgaaagtc cgaccacacc agagcgagca
    33841 acttccacaa ttttcgccac atcgcgaatc gatgctaaaa atgcatcaag cttatcgctg
    33901 gtgcctgcta attgaacggt ataaagcgag ggggtgacat cgataatttg cccacggaat
    33961 atttccgtat tacgtttcac ttcgtcacgc ccgtaaccgc tggcctgaat tttcaccagc
    34021 atgatttccc gctcaacatg cgcgccctgc cccaactcac tcacgcgcaa gacatcgacc
    34081 agcttgtgta attgcttttc gatctgctca agcacttttt catcgcccac ggtctggatg
    34141 gtcatacgcg ataatgtcgg atcgtcggtt ggcgcaacgg tcaggctttc aatgttgtag
    34201 ccacgctggg aaaaaaggcc aatcacgcgg gataacgcgc ctgattcatt ttcgagtaag
    34261 actgataata tccggcgcat aatcaggttc tctccgtttt gcttaaccac atttcatcca
    34321 ttccgccccc gcgaatctgc atcgggtaga cgtgctcact gccatcgacg gtaacatcaa
    34381 caaacaccag gcgattattg cgcacctgtt ccagcgcctc gctaagtttg ctttccagct
    34441 catgcggatg agagatctgg atcccgacgt gaccataggc ttccgccaga cggacgaaat
    34501 cgggtagtga ttgcatataa gattgtgaat gacggccgga atagatcatg tcctgccact
    34561 gtttcaccat ccccagatag cggttattga gattcaccac cagtaccggc aactcgtatt
    34621 gcaacgcggt agacagttcc tggatgttca tctgaatact gccgtcgcca gtgacgcaaa
    34681 ccacggtttc ttctggcaac gccattttga cgcccagtgc cgcaggtaaa ccaaaaccca
    34741 tcgtgccgag gccaccggaa ttgatccagc gacgcggttt gtcgaatgga taataaagtg
    34801 cagcaaacat ctggtgctgc ccgacatcgg acgtcacgta agcgtctccc ttcgtcaacc
    34861 gccaaagagt ctcgatcacc gcctgcggtt taatcttttc actgtgagtg tcatatttca
    34921 ggcactgacg agcgcgccac tgttcaatct gctgccacca gtcgcggatc tcatccagcg
    34981 gttgatgggc ggattcttgc gacaggagtt caagcatttg ttcgaggacc tggcgagcat
    35041 cccccacaat cgggatatca gcagtcacgg ttttagaaat ggaagtagga tcaatatcga
    35101 tatgcagaac agtggcattt gggcagtact ttgccagatt attcgtcgtt cggtcatcaa
    35161 atcttacccc gacggcgaaa atcacatccg cgttatgcat cgtcatattg gcttcgtagg
    35221 tgccgtgcat tcccagcatg cccagcgcct gacgatgcgt tgccggaaat gcccccaggc
    35281 ccatcaatga ggaaacaacg ggcagattca acgcctccac cgtttctttc aactgctgat
    35341 ggcagcccgc cgtgattgcc ccaccgccta cgtagacaac cggttttttt gccgccacca
    35401 gcgtttgcag agcacgctta atttgccctt tatgtccggt agtagtggga ttgtaagaac
    35461 gcatactaac cgactccggc cagacatagg gtaatttgtt cgccggatta agaatatctt
    35521 tcggtaaatc aacgactact ggtccaggac gaccacttgc cgccagccag aaagcctttt
    35581 tcagcacctg cggaatgtct tccgtttgct taaccagaaa actgtgttta accaccggtc
    35641 gcgaaatccc caccatgtcg cactcctgaa aggcatcgta acctatcaac gaggtcgcta
    35701 cctgcccgga aaggacaact aatggaatgg aatccatata agcggtggcg atgccggtaa
    35761 tcgcattggt cgcccctgga cccgacgtta ccagcacgac gccgacttcc ccggtcgcac
    35821 gcgccaggcc atcggccata tgcaccgccg cctgctcatg acgaactaat atatgatcaa
    35881 taccacccac ggtatgcaat gcatcgtaaa tatcaaggac tgcgcctccg ggataaccga
    35941 atacttgttt aacgccctga tcgataagcg atcggacgac catctcggct ccagacaaca
    36001 tctccatggc ctgcctcact gtttgacgga aaaaatgtgt aaaacacatt aaccgtccga
    36061 tcttgcttaa gcaattggca gccagagaca taaacgcagg gtaataagaa taaacaggag
    36121 gaaaggtgaa aagaaacgat aaaatcctcc attacgaagg attaaattga caataaatcg
    36181 gctgaatccc acaacttaca gcaatttctc tattttttta attaatccta aaatagagag
    36241 cacacacatt cagaataaaa ttctacattc aataaaaaat gcagaataaa ccagacattc
    36301 atgtctggcc tattctgcat tcagttagcg tttgcaaatt gagactaatt gttcttccat
    36361 ccactgatgg cctttatcgc gcccggcagc ttcatgccag gagagataac aggttctgct
    36421 gttttgtttt aacggcagcg gtaatacctg taattctaag gattcagcga actcttcagc
    36481 cagccaacgc ggcgcaatag cgaccaaatg cgtttgcgac accacgctaa gtacgctcat
    36541 cattgccatg ccctgatacg cgatactggc ttgcttatct accgtgtcat accaaggttg
    36601 actaaatgac gcgaaacgat cgagcgaaac cgccgcatgt tgttcgttat aaacatcatg
    36661 tttcagtaac gggcccttaa ttgttggatg atttttgctg gctaccagca ccatttcatc
    36721 tttaaataat ggcacgctgg taaattcagg acgatggaag tcttcataac taatcacaaa
    36781 ctccgtttcc tgataacgca gctgatgttc agtgttctga tttaatgaag acttgaacat
    36841 aacatgtata tttggcgcaa tctgctcaat gtgattataa atctgcgagg tcagaatgct
    36901 gtctaacggg ctgcaaacac aaagatgaaa tacacgttca ctgctcgcgg gttcaaaacc
    36961 tgaaccaggc aattcatttt gtactagttg caatgcctga cgaactgagc caaaaagttg
    37021 aaatgcgcga gcagtcggtt gaataccacg gccataacga acaaaaagct cgtcattaaa
    37081 catcaccttc aggcgtgcaa cagcgttact gaccgcaggt tgcgacatac ccagaacatg
    37141 agcggcacgg gtaatgtttt gctcctgcat cacggcatcg aaaacggtta ataagttgag
    37201 atcgaccatg cgtagctgtg gcttgcttaa ctccgccgtc tctgaatgat ctgtttgtac
    37261 ctctggcata cttaactcca ctgtcacact taactccctt tcccttattg gaatgcagag
    37321 aaataa
//
LOCUS       DAPGUL010000037        36615 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.037, whole genome shotgun sequence.
ACCESSION   DAPGUL010000037 DAPGUL010000000
VERSION     DAPGUL010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 36615)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36615)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36615
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.037"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            130..633
                     /gene="dps"
                     /locus_tag="RHX21_002019"
                     /gene_synonym="pexB"
     CDS             130..633
                     /gene="dps"
                     /locus_tag="RHX21_002019"
                     /gene_synonym="pexB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001730644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein Dps"
                     /protein_id="HDV1987201.1"
                     /translation="MSTAKLVKSKATNLLYTRNDVSDSEKKATVELLNRQVIQFIDLS
                     LITKQAHWNMRGANFIAVHEMLDGFRTALIDHLDTMAERAVQLGGVALGTTQVINSKT
                     PLKSYPLDIHNVQDHLKELADRYAIVANDVRKAIGEAKDDDTADILTAASRDLDKFLW
                     FIESNIE"
     gene            1037..1783
                     /gene="glnH"
                     /locus_tag="RHX21_002020"
     CDS             1037..1783
                     /gene="glnH"
                     /locus_tag="RHX21_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter substrate-binding
                     protein GlnH"
                     /protein_id="HDV1987202.1"
                     /translation="MKSVLKVSLAALTLAFAVSSHAADKKLVVATDTAFVPFEFKQGD
                     KYVGFDVDLWAAIAKELKLDYELKPMDFSGIIPALQTKNVDLALAGITITDERKKAID
                     FSDGYYKSGLLVMVKANNNDVKSVKDLDGKVVAVKSGTGSVDYAKANIKTKDLRQFPN
                     IDNAYMELGTNRADAVLHDTPNILYFIKTAGNGQFKAVGDSLEAQQYGIAFPKGSDEL
                     RDKVNGALKTLRENGTYNEIYKKWFGTEPK"
     gene            1922..2581
                     /gene="glnP"
                     /locus_tag="RHX21_002021"
     CDS             1922..2581
                     /gene="glnP"
                     /locus_tag="RHX21_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015367581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter permease GlnP"
                     /protein_id="HDV1987203.1"
                     /translation="MQFDWSAIWPAIPLLIEGAKMTLWISVLGLAGGLVIGLLAGFAR
                     TFGGWIANHVALVFIEVIRGTPIVVQVMFIYFALPMAFNDLRIDPFTAAVVTIMINSG
                     AYIAEITRGAVLSIHKGFREAGLALGLSRWETIRYVILPLALRRMLPPLGNQWIISIK
                     DTSLFIVIGVAELTRQGQEIIAGNFRALEIWSAVAVFYLIITLVLSFILRRLERRMKI
                     L"
     gene            2578..3300
                     /gene="glnQ"
                     /locus_tag="RHX21_002022"
     CDS             2578..3300
                     /gene="glnQ"
                     /locus_tag="RHX21_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter ATP-binding protein
                     GlnQ"
                     /protein_id="HDV1987204.1"
                     /translation="MIEFKNVSKHFGPTQVLHNIDLNIAQGEVVVIIGPSGSGKSTLL
                     RCINKLEEITSGDLIVDGLKVNDPKVDERLIRQEAGMVFQQFYLFPHLTALENVMFGP
                     LRVRGANKEEAEKLARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKMMLF
                     DEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDG
                     DPQVLIKNPPSQRLQEFLQHVS"
     gene            3417..5639
                     /gene="ybiO"
                     /locus_tag="RHX21_002023"
     CDS             3417..5639
                     /gene="ybiO"
                     /locus_tag="RHX21_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415329.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel protein"
                     /protein_id="HDV1987205.1"
                     /translation="MRWILFILFCLLGAPAHAVSIPGVTTTTTTDSTTEPAPEPDIEQ
                     KKAAYGALADVLDNDTSRKELIDQLRTVAATPPAEPVPKIVPPTLVEEQTVLQKVTEV
                     SRHYGEALSARFGQLYRNITGSPHKPFNPQTFSNALTHFSMLAVLVFGFYWLIRLCAL
                     PLYRKMGQWARQKNRERSNWLQLPAMIIGAFIIDLLLLALTLFVGQVLSDNLNAGSRT
                     IAFQQSLFLNAFALIEFFKAVLRLIFCPNVAELRPFTIQDESARYWSRRLSWLSSLIG
                     YGLIVAVPIISNQVNVQIGALANVIIMLCMTVWALYLIFRNKKEITQHLLNFAEHSLA
                     FFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFVSG
                     MFSRWLAKTITLSPHTQRNYPELQKRLNGWLSAALKTARILTVCVAVMLLLSAWGLFD
                     FWNWLQNGAGQKTVDILIRIALILFFSAVGWTVLASLIENRLASDIHGRPLPSARTRT
                     LLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVKDIITGV
                     FIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGI
                     GSVVANYDVDRHEDADKANQALKDAVAELMENEEIRGLIIGEPNFAGIVGLSNTAFTL
                     RVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQTYQVLPAPGAAPAEPPPGEPTL
                     "
     gene            complement(5636..6562)
                     /gene="rlmF"
                     /locus_tag="RHX21_002024"
     CDS             complement(5636..6562)
                     /gene="rlmF"
                     /locus_tag="RHX21_002024"
                     /EC_number="2.1.1.181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415328.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(1618)-N(6))-methyltransferase
                     RlmF"
                     /protein_id="HDV1987206.1"
                     /translation="MSAQKPGLHPRNRHHSRYDLATLCQVNPELRQFLTLTPAGEQSV
                     DFANPLAVKALNKALLAHFYAVANWDIPDGFLCPPVPGRADYIHHLADLLAEASGTIP
                     ANASILDIGVGANCIYPLIGVHEYGWRFTGSETSSQALSSAQAIISANPGLNRAIRLR
                     RQKESGAIFNGIIHKNEQYDATLCNPPFHDSAAAARAGSERKRRNLGLNKDDALNFGG
                     QQQELWCEGGEVAFIKKMIEESKGFAKQVMWFTSLVSRGENLPPLYRALTDVGAVKVV
                     KKEMAQGQKQSRFIAWTFMNDEQRRRFVNRQR"
     gene            6838..7098
                     /locus_tag="RHX21_002025"
     CDS             6838..7098
                     /locus_tag="RHX21_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415327.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDV1987207.1"
                     /translation="MKKCLTLLIATVLSGISLTAYAAQPMSNLDSGQLRPAGTVSATG
                     ASNLSDLEDKLAEKAREQGAKGYVINSAGGNDQMFGTATIYK"
     gene            7362..9644
                     /locus_tag="RHX21_002026"
     CDS             7362..9644
                     /locus_tag="RHX21_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catecholate siderophore receptor Fiu"
                     /protein_id="HDV1987208.1"
                     /translation="MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQTNADDTL
                     VVEASTPSLYAPQQSADPKFSRPVADTTRTMTVISEQVIKDQGATNLTDALKNVPGVG
                     AFFAGENGNSTTGDAIYMRGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTD
                     YGRSAPTGSINMISKQPRNDSGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGE
                     KTHDAGRDKVKNERYGVAPSIAFGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSA
                     PSAGTAALNHSGKVDTHNFYGTDSDYDDSTTDTATMRFEHDINDNTTIRNTTRWSRVK
                     QDYLMTAIMGGASNITQPTSDVNSWTWSRTANTKDVSNKILTNQTNLTSTFYTGSIGH
                     DVTTGVEFTRETQTNYGVNPVTLPAVNIYHPDSSIHPGGLTRNGANANGQTDTFAIYA
                     FDTLQITRDFELNGGIRLDNYHTEYDSATACGGSGRGAITCPTGVAKGSPVTTVDTAK
                     SGNLVNWKAGALYHLTENGNVYINYAVSQQPPGGNNFALAQSGSGNSANRTDFKPQKA
                     NTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQNDDGTYSQYGKKRVEGYEISVAGNI
                     TPAWQVIGGYTQQKATIKNGKDVAQDGSSSLPYTPEHAFTLWSQYQATDDISVGAGAR
                     YIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLDFQLNVYNLFDTDYVASINKS
                     GYRYHPGEPRTFLLTANMHF"
     gene            9686..10363
                     /gene="ybiX"
                     /locus_tag="RHX21_002027"
     CDS             9686..10363
                     /gene="ybiX"
                     /locus_tag="RHX21_002027"
                     /EC_number="1.14.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415325.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKHD-type hydroxylase YbiX"
                     /protein_id="HDV1987209.1"
                     /translation="MMYHIPGVLSPQDVARFREQLEQAEWVDGRVTTGAQGAQVKNNQ
                     QVDTRSTLYAALQNEVLNAVNQHALFFAAALPRTLSTPLFNRYQNNETYGFHVDGAVR
                     SHPQNGWMRTDLSATLFLSDPQSYDGGELVVNDTFGQHRVKLPAGDLVLYPSSSLHCV
                     TPVTRGVRVASFMWIQSMIRDDKKRAMLFELDNNIQSLKSRYGESEEILSLLNLYHNL
                     LREWSEI"
     gene            10437..10703
                     /gene="ybiI"
                     /locus_tag="RHX21_002028"
     CDS             10437..10703
                     /gene="ybiI"
                     /locus_tag="RHX21_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-type zinc finger protein YbiI"
                     /protein_id="HDV1987210.1"
                     /translation="MASGWANDDAVNEQINSTIEDAISRARGEIPRGESLDECEECGA
                     PIPQARREAIPGVRLCIHCQQEKDLQKPAYTGYNRRGSKDSQLR"
     gene            10968..11228
                     /locus_tag="RHX21_002029"
     CDS             10968..11228
                     /locus_tag="RHX21_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDV1987211.1"
                     /translation="MKTINTVVAAMALSTLSFGVFAAEPVTASQAQNMNKIGVVSADG
                     ASTLDALEAKLAEKAAAAGASGYSITSATNNNKLSGTAVIYK"
     gene            complement(11456..12541)
                     /gene="hcxB"
                     /locus_tag="RHX21_002030"
     CDS             complement(11456..12541)
                     /gene="hcxB"
                     /locus_tag="RHX21_002030"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxycarboxylate dehydrogenase HcXB"
                     /protein_id="HDV1987212.1"
                     /translation="MESGHRFDAQTLHSFIQAVFRQMGSEEQEAKLVADHLIAANLAG
                     HDSHGIGMIPSYVRSWSQGHLQINHHAKIVKEAGAAVTLDGDRAFGQVAAHEAMALGI
                     EKAHQHGIAAVALHNSHHIGRIGYWAEQCAAAGFVSIHFVSVVGIPMVAPFHGRDSRF
                     GTNPFCVVFPRKDNFPLLLDYATSAIAFGKTRVAWHKGVPVPPGCLIDVNGVPTTNPA
                     VMQESPLGSLLTFAEHKGYALAAMCEILGGALSGGKTTHQETLQTSPDAILNCMTTII
                     INPELFGAPDCSAQTEAFAEWVKASPHDDDKPILLPGEWEVNTRRERQEQGIPLDAGS
                     WQAICDAARQIGMSEETLQAFCQQLAS"
     gene            complement(12682..13644)
                     /gene="ybiB"
                     /locus_tag="RHX21_002031"
     CDS             complement(12682..13644)
                     /gene="ybiB"
                     /locus_tag="RHX21_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein YbiB"
                     /protein_id="HDV1987213.1"
                     /translation="MDYRKIIKEIGRGKNHARDLDRDTARGLYAHMLNGEVPDLELGG
                     VLIALRIKGEGEAEMLGFYEAMQNHTIKLTPPAGKPMPIVIPSYNGARKQANLTPLLA
                     ILLHKLGFPVVVHGVSEDPTRVLTETIFELMGITPTLHGGQAQAKLDEHQPVFMPVGA
                     FCPPLEKQLAMRWRMGVRNSAHTLAKLATPFAEGEALRLSSVSHPEYIGRVAKFFSDI
                     GGRALLMHGTEGEVYANPQRCPQINLIDREGMRVLYEKQDTAGSELLPQAKDPETTAQ
                     WIERCLAGSEPIPESLKIQMACCLVATGEAATISDGLARVNQAF"
     gene            complement(13672..15822)
                     /gene="dinG"
                     /locus_tag="RHX21_002032"
     CDS             complement(13672..15822)
                     /gene="dinG"
                     /locus_tag="RHX21_002032"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase DinG"
                     /protein_id="HDV1987214.1"
                     /translation="MALTAALKAQIAAWYKALQEQIPDFIPRAPQRQMIADVAKTLAG
                     EEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQIYSKDLPLLKK
                     IIPDLKFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDELTPNNQEEQKRCAKLK
                     GDLDTYKWDGLRDHTDIAIDDDLWRRLSTDKASCLNRNCYYYRECPFFVARREIQEAE
                     VVVANHALVMAAMESEAVLPDPKNLLLVLDEGHHLPDVARDALEMSAEITAPWYRLQL
                     DLFTKLVATCMEQFRPKTIPPLAIPERLNAHCEELYELIASLNNILNLYMPAGQEAEH
                     RFAMGELPDEVLEICQRLAKLTEMLRGLAELFLNDLSEKTGSHDIVRLHRLILQMNRA
                     LGMFEAQSKLWRLASLAQSSGAPVTKWATREEREGQLHLWFHCVGIRVSDQLERLLWR
                     SIPHIIVTSATLRSLNSFSRLQEMSGLKEKAGDRFVALDSPFNHCEQGKIVIPRMRVE
                     PSIDNEEQHIAEMAAFFREQVESKKHLGMLVLFASGRAMQRFLDYVTDLRLMLLVQGD
                     QPRYRLVELHRKRVANGEHSVLVGLQSFAEGLDLKGDLLSQVHIHKIAFPPIDSPVVI
                     TEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRLLTKNYGKR
                     LLDALPVFPIEQPEVPEGIVKKKEKTKSPRRRRR"
     gene            15942..16424
                     /gene="ybiA"
                     /locus_tag="RHX21_002033"
     CDS             15942..16424
                     /gene="ybiA"
                     /locus_tag="RHX21_002033"
                     /EC_number="3.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-glycosidase YbiA"
                     /protein_id="HDV1987215.1"
                     /translation="MPVRAQRIQHVMQDTIINFYSTSDDYGDFSNFAAWPIKVDGKTW
                     PTSEHYFQAQKFLDEKYREEIRRVSSPMVAARMGRDRSKPLRKNWESVKEQVMRKALR
                     AKFEQHPELRALLLATAPAKLVEHTENDAYWGDGGNGKGKNRLGYLLMELREQLAIEK
                     "
     gene            complement(16656..18017)
                     /gene="rhlE"
                     /locus_tag="RHX21_002034"
     CDS             complement(16656..18017)
                     /gene="rhlE"
                     /locus_tag="RHX21_002034"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase RhlE"
                     /protein_id="HDV1987216.1"
                     /translation="MSFDSLGLSPDILRAVAEQGYREPTPIQQQAIPAVLEGRDLMAS
                     AQTGTGKTAGFTLPLLQHLITRQPHAKGRRPVRALILTPTRELAAQIGENVRDYSKYL
                     NIRSLVVFGGVSINPQMMKLRGGVDVLVATPGRLLDLEHQNAVKLDQVEILVLDEADR
                     MLDMGFIHDIRRVLTKLPAKRQNLLFSATFSDDIKALAEKLLHNPLEIEVARRNTASD
                     QVTQHVHFVDKKRKRELLSHMIGKGNWQQVLVFTRTKHGANHLAEQLNKDGIRSAAIH
                     GNKSQGARTRALADFKSGDIRVLVATDIAARGLDIEELPHVVNYELPNVPEDYVHRIG
                     RTGRAAATGEALSLVCVDEHKLLRDIEKLLKKEIPRIAIPGYEPDPSIKAEPIQNGRQ
                     QRGGGRGQGGGRGQQQPRRGEGGAKSASAKPAEKPSRRLGDAKPAGEQQRRRRPRKPT
                     AAQ"
     gene            18246..18917
                     /gene="cecR"
                     /locus_tag="RHX21_002035"
     CDS             18246..18917
                     /gene="cecR"
                     /locus_tag="RHX21_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415317.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CecR"
                     /protein_id="HDV1987217.1"
                     /translation="MNNPAMTIKGEQAKKQLIAAALAQFGEYGMNATTREIAAQAGQN
                     IAAITYYFGSKEDLYLACAQWIADFIGEQFRPHAEEAECLFAQPQPDRAAIRELILRA
                     CRNMIKLLTQDDTVNLSKFISREQLSPTAAYHLVHEQVISPLHSHLTRLIAAWTGCDA
                     NDTRMILHTHALIGEILAFRLGKETILLRTGWTAFDEEKTELINQTVTCHIDLILQGL
                     SQRSL"
     gene            18920..19915
                     /gene="hlyD"
                     /locus_tag="RHX21_002036"
     CDS             18920..19915
                     /gene="hlyD"
                     /locus_tag="RHX21_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308900.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secretion protein HlyD"
                     /protein_id="HDV1987218.1"
                     /translation="MKKPVVIGLAVVVLAAVVAGGYWWYQSRQDNGLTLYGNVDIRTV
                     NLSFRVGGRVESLAVDEGDAIKAGQVLGELDHKPYEIALMQAKAGVSVAQAQYDLMLA
                     GYRDEEIAQAAAAVKQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQAT
                     LKSAQDKLRQYRSGNREQDIAQAKASLEQAQAQLAQAELNLQDSTLIAPSDGTLLTRA
                     VEPGTVLNEGGTVFTVSLTRPVWVRAYVDERNLDQAQPGRKVLLYTDGRPDKPYHGQI
                     GFVSPTAEFTPKTVETPDLRTDLVYRLRIVVTDADDALRQGMPVTVQFGDEAGHE"
     gene            19908..21644
                     /locus_tag="RHX21_002037"
     CDS             19908..21644
                     /locus_tag="RHX21_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308899.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDV1987219.1"
                     /translation="MNDAVITLNGLEKRFPGMDKPAVAPLDCTIHAGYVTGLVGPDGA
                     GKTTLMRMLAGLLKPDSGNATVIGFDPIKNDGALHAVLGYMPQKFGLYEDLTVMENLN
                     LYADLRSVTGEARKQTFARLLEFTSLGPFTGRLAGKLSGGMKQKLGLACTLVGEPKVL
                     LLDEPGVGVDPISRRELWQMVHELAGEGMLILWSTSYLDEAEQCRDVLLMNEGELLYQ
                     GEPKALTQTMAGRSFLMTSPHEGNRKLLQRALKLPQVSDGMIQGKSVRLILKKEATPD
                     DIRHADGMPEININETTPRFEDAFIDLLGGAGTSESPLGAILHTVEGTPGETVIEAKE
                     LTKKFGDFAATDHVNFAVKRGEIFGLLGPNGAGKSTTFKMMCGLLVPTSGQALVLGMD
                     LKESSGKARQHLGYMAQKFSLYGNLTVEQNLRFFSGVYGLRGRAQNEKISRMSEAFGL
                     KSIASHATDELPLGFKQRLALACSLMHEPDILFLDEPTSGVDPLTRREFWLHINSMVE
                     KGVTVMVTTHFMDEAEYCDRIGLVYRGKLIASGTPDDLKAQSANDEQPDPTMEQAFIQ
                     LIHDWDKEHSNE"
     gene            21637..22770
                     /locus_tag="RHX21_002038"
     CDS             21637..22770
                     /locus_tag="RHX21_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV1987220.1"
                     /translation="MSNPILSWRRVRALCVKETRQIVRDPSSWLIAVVIPLLLLFIFG
                     YGINLDSSKLRVGILLEQRSEAALDFTHTMTGSPYIDATISDNRQELIAKMQAGKIRG
                     LVVIPVDFAEQMERANATAPIQVITDGSEPNTANFVQGYVEGIWQIWQMQRAEDNGQT
                     FEPLIDVQTRYWFNPAAISQHFIIPGAVTIIMTVIGAILTSLVVAREWERGTMEALLS
                     TEITRTELLLCKLIPYYFLGMLAMLLCMLVSVFILGVPYRGSLLILFFISSLFLLSTL
                     GMGLLISTITRNQFNAAQVALNAAFLPSIMLSGFIFQIDSMPAVIRAVTYIIPARYFV
                     STLQSLFLAGNIPVVLVVNVLFLIASAVMFIGLTWLKTKRRLD"
     gene            22781..23887
                     /locus_tag="RHX21_002039"
     CDS             22781..23887
                     /locus_tag="RHX21_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV1987221.1"
                     /translation="MFHRLWTLIRKELQSLLREPQTRAILILPVLIQVILFPFAATLE
                     VTNATIAIYDEDNGEHSVELTQRFARASAFTHVLLLKSPQEIRPTIDTQKALLLVRFP
                     ADFSRKLDTFQTAPLQLILDGRNSNSAQIAANYLQQIVKNYQQELLEGKPKPNNSELV
                     VRNWYNPNLDYKWFVVPSLIAMITTIGVMIVTSLSVAREREQGTLDQLLVSPLTTWQI
                     FIGKAVPALIVATFQATIVLAIGIWAYQIPFAGSLALFYFTMVIYGLSLVGFGLLISS
                     LCSTQQQAFIGVFVFMMPAILLSGYVSPVENMPVWLQNLTWINPIRHFTDITKQIYLK
                     DASLDIVWNSLWPLLVITATTGSAAYAMFRRKVM"
     gene            complement(23849..24259)
                     /locus_tag="RHX21_002040"
     CDS             complement(23849..24259)
                     /locus_tag="RHX21_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhQ family protein"
                     /protein_id="HDV1987222.1"
                     /translation="MKWQQRVRVATGLSCWQIMLHLLVVALLVVGWMSKTLVHVGVGL
                     CALYCVTVVMMLVFQRHPEQRWREVADVLEELTTTWYFGAALIVLWLLSRVLENNFLL
                     AIAGLAILAGPAVVSLLAKDKKLHHLTSKHRVRR"
     gene            24392..25153
                     /locus_tag="RHX21_002041"
     CDS             24392..25153
                     /locus_tag="RHX21_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HDV1987223.1"
                     /translation="MPDQTQQFSFKVLTINIHKGFTAFNRRFILPELRDAVRTVSADI
                     VCLQEVMGAHEVHPLHVENWPDTSHYEFLADTMWSDFAYGRNAVYPEGHHGNAVLSRY
                     PIEHYENRDVSVDGAEKRGVLYCRIVPPMTGKAIHVMCVHLGLREAHRQAQLAMLAEW
                     VNELPDGEPVLVAGDFNDWRQKANHPLKVQAGLDEIFTRVHGRPARTFPVQFPLLRLD
                     RIYVKNASASAPTALPLRTWRHLSDHAPLSAEIHL"
     gene            25150..26391
                     /gene="clsB"
                     /locus_tag="RHX21_002042"
     CDS             25150..26391
                     /gene="clsB"
                     /locus_tag="RHX21_002042"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase ClsB"
                     /protein_id="HDV1987224.1"
                     /translation="MKCSWREGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFE
                     DDVGKQLHAALLAAAQRGVKAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLF
                     GMRTNVFRRMHRKIVVIDARIAFIGGLNYSAEHMSSYGPEAKQDYAVRLEGPIVEDIL
                     QFELENLPGQSAARRWWRRHHKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQ
                     ARREVIIANAYFFPGYRFLHALRKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVK
                     GGVQVFEYRRRPLHGKVALMDDHWATVGSSNLDPLSLSLNLEANVIIHDRHFNQTLRD
                     NLNGIIAADCQQVDETMLPKRTWWNLTKSVLAFHFLRHFPALVGWLPAHTPRLAQVDP
                     PAQPTMETQDRVETENTGVKP"
     gene            26391..27347
                     /locus_tag="RHX21_002043"
     CDS             26391..27347
                     /locus_tag="RHX21_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0104 family protein"
                     /protein_id="HDV1987225.1"
                     /translation="MSKSHPRWRLAKKILTWLFFIAVIVLLVVYAKKVDWEEVWKVIR
                     DYNRVALLSAVGLVVVSYLIYGCYDLLARFYCGHKLAKRQVMLVSFICYAFNLTLSTW
                     VGGIGMRYRLYSRLGLPGSTITRIFSLSITTNWLGYILLAGIIFTAGVVELPDHWYVD
                     QTTLRILGIGLLMIIAVYLWFCAFAKHRHMTIKGQKLVLPSWKFALAQMLISSVNWMV
                     MGAIIWLLLGQSVNYFFVLGVLLVSSIAGVIVHIPAGIGVLEAVFIALLAGEHTSKGS
                     IIAALLAYRVLYYFIPLLLALICYLLLESQAKKLRAKNEAAM"
     gene            complement(27383..28096)
                     /locus_tag="RHX21_002044"
     CDS             complement(27383..28096)
                     /locus_tag="RHX21_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003570877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HDV1987226.1"
                     /translation="MNSRSANNITNDFQHEARILNSIWLITALGLVATAGLAWGAKYL
                     EITATKYDSPTMYVAIGLLLVCMYGLSKDINKINAVIAGVIYLFLLSLVAIVVASLAP
                     VPAIIVVFSTAGAMFLISMLAGLLFNVDPGSHRFIIMMTLTGLALVIIMNAALMSERP
                     VWVISCLMIVLWSGIISHGRNKLLELAGKCHSEELWSPVRCAVTGALTLYYYFIGFFG
                     ILAAIAITLVWQRHTRFFH"
     gene            complement(28166..28813)
                     /locus_tag="RHX21_002045"
     CDS             complement(28166..28813)
                     /locus_tag="RHX21_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001693847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HDV1987227.1"
                     /translation="MLLLIWWLTAAGVWATAGCAWIFQHLHWVTSQKSPGAFVFALAA
                     LIIGGLWLNNALKRLNVSGACLVYLLIILLVGFLFASLYTFSSIATVMGITGGMFAAM
                     ALICSCSNRVIPPVRQLYSYIFCGLSIAFVVNLILTSSFSVWLASILTVFIWGITAAC
                     EATTLEDLIRVADTSEISGSLRCIVPGAITLYFSILSVLFRITVTVLEFINGLVW"
     gene            complement(29015..29719)
                     /locus_tag="RHX21_002046"
     CDS             complement(29015..29719)
                     /locus_tag="RHX21_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HDV1987228.1"
                     /translation="MDRFPRSDSIVQPRAGLQTYMAQVYGWMTVGLLLTAFVAWYAAN
                     SAAVMELLFTNRVFLIGLIIAQLALVIVLSAMIQKLSAGVTTMLFMLYSALTGLTLSS
                     IFIVYTAASIASTFVVTAGMFGAMSLYGYTTKRDLSGFGNMLFMALIGIVLASLVNFW
                     LKSEALMWAVTYIGVIVFVGLTAYDTQKLKNMGEQIDTRDTSNLRKYSILGALTLYLD
                     FINLFLMLLRIFGNRR"
     gene            complement(29856..30308)
                     /gene="moaE"
                     /locus_tag="RHX21_002047"
     CDS             complement(29856..30308)
                     /gene="moaE"
                     /locus_tag="RHX21_002047"
                     /EC_number="2.8.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin synthase catalytic subunit MoaE"
                     /protein_id="HDV1987229.1"
                     /translation="MAETKIVVGPQPFSVGEEYPWLAERDEDGAVVTFTGKVRNHNLG
                     DSVKALTLEHYPGMTEKALAEIVDEARNRWPLGRVTVIHRIGELWPGDEIVFVGVTSA
                     HRSSAFEAGQFIMDYLKTRAPFWKREATPEGDRWVEARESDQQAAKRW"
     gene            complement(30310..30555)
                     /gene="moaD"
                     /locus_tag="RHX21_002048"
     CDS             complement(30310..30555)
                     /gene="moaD"
                     /locus_tag="RHX21_002048"
                     /EC_number="2.8.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin synthase sulfur carrier subunit"
                     /protein_id="HDV1987230.1"
                     /translation="MIKVLFFAQVRELVGTDATEVAADFPTVEALRQHMAAQSDRWAL
                     ALEDGKLLAAVNQTLVSFDHPLTDGDEVAFFPPVTGG"
     gene            complement(30548..31033)
                     /gene="moaC"
                     /locus_tag="RHX21_002049"
     CDS             complement(30548..31033)
                     /gene="moaC"
                     /locus_tag="RHX21_002049"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HDV1987231.1"
                     /translation="MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMI
                     IDGRHHKGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETL
                     CRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEAD
                     D"
     gene            complement(31036..31548)
                     /gene="moaB"
                     /locus_tag="RHX21_002050"
     CDS             complement(31036..31548)
                     /gene="moaB"
                     /locus_tag="RHX21_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor biosynthesis protein B"
                     /protein_id="HDV1987232.1"
                     /translation="MSQVSTEFIPTRIAILTVSNRRGEEDDTSGHYLRDSAQEAGHHV
                     VDKAIVKENRYAIRAQVSAWIASDDVQVVLITGGTGLTEGDQAPEALLPLFDREVEGF
                     GEVFRMLSFEEIGTSTLQSRAVAGVANKTLIFAMPGSTKACRTAWENIIAPQLDARTR
                     PCNFHPHLKK"
     gene            complement(31570..32559)
                     /gene="moaA"
                     /locus_tag="RHX21_002051"
     CDS             complement(31570..32559)
                     /gene="moaA"
                     /locus_tag="RHX21_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HDV1987233.1"
                     /translation="MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNK
                     GFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNG
                     YRLERDVANWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDAAFEVGFEKVK
                     VNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELL
                     RRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLF
                     GEGGVNLRDLLEDDTQQQALEARISAALREKKQTHFLHQNNTGITQNLSYIGG"
     regulatory      complement(32547..32691)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01055"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="molybdenum cofactor riboswitch; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="molybdenum cofactor"
                     /db_xref="RFAM:RF01055"
     gene            32956..33864
                     /gene="yvcK"
                     /locus_tag="RHX21_002052"
     CDS             32956..33864
                     /gene="yvcK"
                     /locus_tag="RHX21_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HDV1987234.1"
                     /translation="MRNRTLADLDRVVALGGGHGLGRVLSSLSSLGSRLTGIVTTTDN
                     GGSTGRIRRSEGGIAWGDMRNCLNQLITEPSVASAMFEYRFGGNGELSGHNLGNLMLK
                     ALDHLSVRPLEAINLIRNLLKVDTHLIPMSEHPVDLMAIDDQGHEVYGEVNIDQLTTP
                     IQELLLTPNVPATREAVHAINEADLIIIGPGSFYTSLMPILLLKEIAQALRRTPAPMV
                     YIGNLGRELSLPAANLKLESKLAIMEQYVGKKVIDAVIVGPKVDVSAVKERIVIQEVL
                     EASDIPYRHDRQLLHNALEKALQALG"
     gene            complement(34056..36077)
                     /gene="uvrB"
                     /locus_tag="RHX21_002053"
     CDS             complement(34056..36077)
                     /gene="uvrB"
                     /locus_tag="RHX21_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HDV1987235.1"
                     /translation="MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSG
                     KTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYV
                     PSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
                     LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFD
                     EEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRKVLLE
                     NNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGL
                     LVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYV
                     SATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVL
                     VTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLRE
                     GLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIG
                     ETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVP
                     MDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS"
BASE COUNT         8778 a         9714 c         9388 g         8735 t
ORIGIN      
        1 ttagttttgt ttttcacgct tgttaccact attagtgtga taggaacagc cagaatagcg
       61 gaacacatag ccggtgctat acttagtctc gttaattact gggacataac atcaagagga
      121 tatgaaatta tgagtaccgc taaattagtt aaatcaaaag cgaccaatct gctttatacc
      181 cgcaacgatg tctccgacag cgagaaaaaa gcaacagtag agttgctgaa tcgccaggtt
      241 atccagttta ttgatctttc tttgattacc aaacaagcgc actggaacat gcgcggcgct
      301 aacttcattg ccgtacatga aatgctggat ggcttccgca ccgcactgat cgatcatctg
      361 gataccatgg cagaacgtgc agtgcagctg ggcggtgtag ctctggggac cactcaagtt
      421 atcaacagca aaaccccgct gaaaagttac ccgctggaca tccacaacgt tcaggatcac
      481 ctgaaagaac tggctgaccg ttacgcaatc gtcgctaatg acgtacgcaa agcgattggc
      541 gaagcgaaag atgacgacac cgcagatatc ctgaccgccg cgtctcgcga cctggataaa
      601 ttcctgtggt ttatcgagtc taacatcgaa taaatccatc gctgatggtg cagaacttta
      661 gtacccgata aaagcggctt cctgacagga ggccgttttg ttttgcagcc cacctcaacg
      721 cacttattta gtgcatccat ctgctatctc cagctgatta agtaaatttt ttgtatccac
      781 atcatcacac aatcgttaca taaagattgt tttttcatca ggttttacgc taaataatca
      841 ctgtgttgag tgcacaattt tagcgcacca gattggtgcc ccagaatggt gcatcttcag
      901 ggtattgccc tataaatcgt gcatcacgtt tttgccgcat ctcgaaaaat caaggagttg
      961 caaaactggc acgatttttt catatatgtg aatgtcacgc aggggatcgt cccgtggata
     1021 gaaaaaagga aatgctatga agtctgtatt aaaagtttca ctggctgcac tgaccctggc
     1081 ttttgcggtt tcttctcatg ccgcggataa aaaattagtt gtcgcgacgg ataccgcctt
     1141 cgttccgttt gaatttaaac agggcgataa atatgtgggc tttgacgttg atctgtgggc
     1201 tgccatcgct aaagagctga agctggatta cgaactgaag ccgatggatt tcagtgggat
     1261 cattccggca ctgcaaacca aaaacgtcga tctggcgctg gcgggcatta ccatcaccga
     1321 cgagcgtaaa aaagcgatcg atttctctga cggctactac aaaagcggcc tgttagtgat
     1381 ggtgaaagct aacaataacg atgtgaaaag cgtgaaagat ctcgacggga aagtggttgc
     1441 tgtgaagagc ggtactggct ccgttgatta cgcgaaagca aacatcaaaa ctaaagatct
     1501 gcgtcagttc ccgaacatcg ataacgccta tatggaactg ggcaccaacc gcgcagacgc
     1561 cgttctgcac gatacgccaa acattctgta cttcatcaaa accgccggta acggtcagtt
     1621 caaagcggta ggtgactctc tggaagcgca gcaatacggt attgcgttcc cgaaaggtag
     1681 cgacgagctg cgtgacaaag tcaacggcgc gttgaaaacc ctgcgcgaga acggaactta
     1741 caacgaaatc tacaaaaaat ggttcggtac tgaaccgaaa taataacgct acacctgtaa
     1801 aacgcactgg cagttccctc tcccctatgg ggagaggatt agggtgaggg gcgcaaaccc
     1861 gctccggggc cattaattac cctgaatttg attatttaca ccacggtaac aggaacaaca
     1921 tatgcagttt gactggagtg ccatctggcc tgccattccg cttctgattg aaggtgccaa
     1981 aatgaccctg tggatttcgg tcctcggtct ggcaggcggt ctggtaatcg gattgctggc
     2041 aggttttgca cgcaccttcg gtggttggat agccaaccac gtcgcgctgg tctttattga
     2101 agtgatccgc ggcacaccta tcgtcgtcca ggtgatgttt atctatttcg ccctgccgat
     2161 ggcgtttaac gacttacgca tcgacccatt tactgcggcg gtggtcacca tcatgatcaa
     2221 ctccggcgcg tacattgcgg aaatcacgcg tggtgcggtg ctgtctattc acaaaggttt
     2281 tcgtgaagca ggactggcgc tcggtctttc acgttgggaa accattcgct acgtcatttt
     2341 accgctggca ctgcgtcgta tgctgccgcc gctgggtaac cagtggatca tcagcattaa
     2401 agacacctcg ctgtttattg ttatcggcgt ggcggaactg acccgtcagg ggcaagaaat
     2461 tattgccggt aacttccgcg cccttgagat ctggagcgcc gtggcggtgt tctatctgat
     2521 tattaccctg gtgctgagct ttattctgcg tcgtctggaa agaaggatga aaatcctgtg
     2581 attgaattta aaaacgtctc caagcatttt ggtccaaccc aggtgctgca caatatcgat
     2641 ttgaacattg ctcagggcga agtcgtggtg attatcgggc cgtccggttc cggtaaatcg
     2701 accctgctgc gctgcatcaa caaactggaa gaaatcacct ccggcgatct gattgtcgat
     2761 ggcctgaagg ttaacgatcc gaaagttgac gagcgcctga ttcgccagga agcgggtatg
     2821 gtgttccagc agttttacct cttcccgcat ctgacggcgc tggaaaacgt catgtttggt
     2881 ccgctacgcg tgcgtggcgc gaacaaagaa gaggcggaaa aactggcgcg tgagctgctg
     2941 gcgaaagtcg gtctggcaga acgtgcacat cactaccctt ccgaactttc tggtggtcaa
     3001 cagcagcgtg tggcgattgc ccgcgcgctg gcggtgaagc cgaaaatgat gctgtttgat
     3061 gaaccgactt ccgctcttga cccggaactg cgccatgaag tgctgaaggt tatgcaggat
     3121 ctggctgaag aagggatgac gatggtgatc gtgacccacg aaatcggttt tgccgagaaa
     3181 gtagcttcgc ggctgatctt tatcgacaaa ggccggattg cggaagatgg cgatccgcag
     3241 gtattgatca agaacccgcc gagccagcgc ttgcaggaat ttttgcagca cgtctcttaa
     3301 cttctctgcc tccctttcac ccgaaaggga ggcacaccag attcctctca tttaaaatcg
     3361 cccctccccc agcatctata cttatctttt tgctctgttt tctcactgga ggagtcatgc
     3421 ggtggatcct gttcatcctc ttctgcctgc tgggcgcacc tgcccacgcg gtatccatac
     3481 ccggcgttac aaccacaacg acaacggact caacgactga accggccccg gaaccggata
     3541 tcgaacaaaa aaaagcggcc tatggcgcac tggcggatgt gctggataac gacacctcgc
     3601 gtaaagaatt gatcgaccag ttgcgtactg tcgccgcgac gccccctgcg gaaccggtcc
     3661 cgaagatcgt gccgccgacg ctggttgaag agcaaaccgt gctgcaaaag gtcaccgaag
     3721 tcagccgcca ttatggtgaa gccctttccg cccgtttcgg acaactttat cgcaatatca
     3781 ccggctcccc gcataagccg tttaatccac aaaccttcag caatgcgttg acccattttt
     3841 caatgttagc ggtattagtg tttggttttt actggctgat tcgtctgtgc gcactgccgc
     3901 tgtatcgcaa aatgggccag tgggcgcggc aaaaaaatcg cgaacgcagc aactggctgc
     3961 agcttccggc gatgattatc ggggcgttta ttatcgacct actgttactg gcactgacat
     4021 tgtttgtcgg ccaggtatta agcgacaacc tgaatgcggg cagtcgcacc atcgctttcc
     4081 aacaaagttt gtttctcaac gcctttgccc tgattgaatt tttcaaagcc gtactacgcc
     4141 tgattttttg cccaaacgtg gctgaactgc gcccgttcac gattcaggac gagagcgccc
     4201 gttactggag tcgtcgcctg agctggttaa gcagtttgat aggttatggc ctgattgtgg
     4261 ccgtgccgat tatctctaat caggtgaatg tacagatagg tgcgctggcg aacgtcatca
     4321 ttatgctgtg catgaccgtc tgggcgttgt acctgatctt tcgtaataaa aaagagatta
     4381 cccagcattt gctcaacttt gcggagcatt cgctggcctt tttcagcctg tttatccgcg
     4441 cctttgcgct ggtgtggcac tggctggcaa gcgcctattt tatcgtgctg tttttctttt
     4501 cgttgttcga tccgggcaac agcctgaaat ttatgatggg tgcaacggtg cgcagcctgg
     4561 cgattattgg tattgcagcg tttgtttccg gtatgttttc ccgctggctg gcaaaaacca
     4621 tcactctctc gccacatact cagcgtaact atccagagtt gcaaaaacgg ctgaatggct
     4681 ggctttcggc ggcgctgaaa acggcgcgta ttctgaccgt ctgcgtggcg gtaatgttgc
     4741 tgttgagcgc atggggattg ttcgatttct ggaactggct gcaaaacggc gcggggcaga
     4801 aaaccgtaga tatcctgatc cgtatcgcac ttattctttt tttctcggcg gttggctgga
     4861 cggtgctcgc cagtttgatc gaaaaccggc tggcttcgga tattcatggc cgcccgctac
     4921 ccagcgcccg tacgcgtacc ctgctgacgc tgttccgtaa cgcgctggcg gtgattatca
     4981 gtaccatcac catcatgatt gtgttgtcgg aaatcggcgt caatatcgcg ccattgctgg
     5041 caggtgccgg ggcattaggt ctggctatct cgtttggttc gcaaacgctg gtgaaagata
     5101 ttatcaccgg ggtatttatt cagtttgaaa acggcatgaa cactggagat ttggtaacta
     5161 tcgggccgtt gaccggcaca gtggaacgga tgtcgattcg ctccgtgggc gtgcgccagg
     5221 ataccggggc gtatcacatc attccgtggt cttcgataac cacctttgct aacttcgtcc
     5281 gcggtattgg ttcggtagtg gcaaactacg atgttgatcg ccatgaagat gctgataaag
     5341 ccaatcaggc actgaaagat gcggtagcgg aattgatgga aaacgaagaa attcgcgggc
     5401 tgattattgg tgaaccgaat tttgccggga ttgtcggctt aagcaatacc gcgtttacac
     5461 tgcgtgtttc gttcaccacg ctgccactca aacagtggac ggtacgcttt gccctcgaca
     5521 gccaggtgaa aaaacatttc gacctggcgg gcgttcgcgc gccagtgcag acttatcagg
     5581 tgctgcctgc tccgggcgcg gccccggctg aaccgccgcc gggggagcca acgctttaac
     5641 gttggcgatt aacaaaacgg cggcgctgct cgtcgttcat aaaggtccag gcaataaagc
     5701 gactctgctt ttgcccctgg gccatctctt tttttaccac cttcaccgcg cccacgtcgg
     5761 tcagagcacg atacaacggc ggtaagtttt caccacgaga taccagcgag gtaaaccaca
     5821 tcacctgctt cgcgaagcct ttgctctctt caatcatctt tttgataaag gcgacttcac
     5881 caccttcaca ccacaactcc tgttgctgac caccaaagtt cagtgcatcg tctttgttca
     5941 gccccaggtt acggcgttta cgctcactac ctgcccgcgc tgcagcggcg gaatcgtgga
     6001 atggcgggtt acacaaggtc gcgtcgtatt gctcgttttt atggatgatg ccgttaaaaa
     6061 ttgccccact ctctttttgc cgacgcagac gaatggcgcg gttaagcccc ggattagcac
     6121 tgataatcgc ctgcgcactg cttaacgcct ggctgctggt ttcactaccg gtaaaacgcc
     6181 agccatattc atgtacgcca atcagcggat aaatacagtt cgcaccaacg ccgatatcca
     6241 gaatgctggc attcgctgga attgttccgc ttgcttcagc cagtaaatcg gcaaggtgat
     6301 gaatataatc cgcccggccc ggtactggtg ggcagagaaa accgtcgggg atatcccagt
     6361 tcgctacggc gtaaaaatgg gccagcaacg ccttattgag cgccttcacc gccagcggat
     6421 tggcaaagtc tacgctttgc tccccggcgg gtgtaagcgt gaggaattgc ctgagttcag
     6481 gattgacctg acaaagcgtg gcgagatcgt agcggctgtg atgacggttg cgcggatgca
     6541 accccggttt ctgggcggac atagcattct cctttaagca gcggcgtaag atacccgcat
     6601 aacgcgacag ggtaaatatc tggctgcgtt tatcattccc caaaacctta acatggctat
     6661 ggtttatggc aattcatcat aaaaatcagc attatgcatg tcattgattt gtcttatttt
     6721 gtaaaaatat atcgttcaaa aaataagcac atctctgtca attttttgcg tcattttcat
     6781 cgcccaggcg acctacactt atcaggcact acccgttgta tttatgagga tgtcattatg
     6841 aaaaagtgcc tcacactact gattgccacc gtcctgagcg gaatctctct cacggcttat
     6901 gccgcgcaac cgatgagtaa cctggacagc ggtcagctac ggcccgccgg taccgtttcg
     6961 gcaactggcg catcaaacct aagcgatctg gaggataaac tggcagaaaa agcgcgcgag
     7021 caaggcgcga aaggttatgt cattaattcc gcaggcggaa atgaccagat gttcggtact
     7081 gcaaccatct acaaataacc ccaccaacgt aactgcattc gcctctggat gcagttttcg
     7141 cctgttttgt aatcaaaaaa catcaaatat gaacgcaatg taaataaatg tatttctttt
     7201 tcgcgcaatg ggtgatagaa aatcgcgcca attgataatg cttatcaaaa ttattatcac
     7261 ttgcacgaac actatcacga gattaacagt ggcatcgcat ccgcagagag gctttctcgt
     7321 ggcagtgaaa atttcaacat ataaaaaaag tcacctgcaa aatggaaaac aatcgcaatt
     7381 tccctgccag acaatttcat tcgctcacgt tctttgccgg tctttgtatt ggcatcacgc
     7441 ctgtggctca ggcactcgcc gccgaagggc aaactaacgc ggatgacacg ctggttgtcg
     7501 aagcatcaac gccttcgctt tatgcgccac aacaatctgc cgatccgaaa ttctcgcgtc
     7561 cggtagcgga tactacccgc acgatgacgg tgatttctga acaagtgatt aaagatcagg
     7621 gcgcaaccaa ccttaccgac gcgctcaaaa acgtccccgg cgtgggtgcg ttttttgcgg
     7681 gtgagaacgg taactccacc actggcgacg ccatttatat gcgcggtgct gatacctcta
     7741 acagtattta tattgatggc attcgcgata tcggcagcgt ctcgcgcgac accttcaata
     7801 ctgagcaggt cgaagtgatt aaagggcctt ccggcaccga ctacgggcgc agcgcgccga
     7861 cgggctcgat caatatgatc agcaagcagc cgcgcaatga ttccggcatt gacgcctccg
     7921 ccagtattgg cagcgcctgg ttccgccgcg gcacgctgga cgtcaatcag gtcattggtg
     7981 ataccactgc ggtgcgcctg aatgtgatgg gcgaaaaaac gcacgatgcc ggacgcgaca
     8041 aagtcaaaaa tgagcgttac ggcgtcgccc cttctatcgc ttttggcctt ggtacagcga
     8101 atcgtttgta tcttaattat ctgcatgtca cccagcacaa cacgccagac ggcggcattc
     8161 cgaccatcgg tttgccgggt tattctgccc catctgcggg aacagcggct ctgaatcatt
     8221 ccggaaaagt tgatactcat aacttttacg gcacggattc cgattacgac gattcgacca
     8281 ccgacaccgc caccatgcgt tttgagcacg acatcaacga taacaccacc attcgcaata
     8341 ctacccgttg gtcgcgcgta aagcaggatt acctgatgac ggcgattatg ggcggggcgt
     8401 cgaatattac tcagcccacc agcgatgtga atagctggac ctggtcacgc acggcgaata
     8461 ccaaagatgt gagtaataaa attctcacca accagaccaa cctgacctcg acgttctata
     8521 ccggttctat cggtcatgat gtcactaccg gcgtggaatt tacccgtgaa acgcagacta
     8581 actacggcgt taatccggtg acgttacccg cggtaaatat ttatcatcct gacagcagca
     8641 ttcatcccgg cggcctgacg cgcaacggcg caaacgccaa tggtcagacg gataccttcg
     8701 caatttacgc cttcgatacg ctgcaaatca cccgtgattt tgagctgaac ggcgggatcc
     8761 gtctggataa ttatcatact gaatatgaca gtgccaccgc ctgcggcggc agcggacgcg
     8821 gtgccatcac ctgcccaact ggtgtggcaa aaggttctcc ggtcaccacc gtcgacaccg
     8881 ccaagtcggg caatctggtg aactggaaag ccggggcgct gtatcacctg acggaaaacg
     8941 gtaatgtcta tattaactat gccgtttccc agcagcctcc gggcggcaac aacttcgccc
     9001 ttgcgcagtc tggcagcggt aacagtgcca accgcaccga ttttaaaccg caaaaagcca
     9061 acaccagcga gattggcacc aaatggcagg ttctggataa acgcctgttg ctcaccgccg
     9121 cgctattccg tactgatatc gaaaatgaag ttgagcaaaa tgatgacgga acttactcgc
     9181 aatacggtaa gaaacgtgtc gaaggctatg agatatccgt ggccgggaat atcactcccg
     9241 cgtggcaggt gattggcggc tatacccagc aaaaagcaac catcaaaaac ggcaaagatg
     9301 ttgcccagga tggttcctca tcgctgccgt ataccccgga gcacgccttc accttatgga
     9361 gccagtatca ggcaaccgat gatatctctg ttggcgcggg cgcacgctat atcggcagta
     9421 tgcataaagg ttcagacggc gcggtgggaa cgccagcgtt taccgaaggt tactgggtcg
     9481 ccgatgccaa actggggtat cgggttaatc gcaatctcga cttccagcta aacgtttaca
     9541 acctgtttga taccgattac gtcgcctcaa tcaacaagag cggctaccgt tatcacccgg
     9601 gcgagccaag aaccttcttg ctcacagcca atatgcattt ctgattcaga tgtggggcgc
     9661 aggccccact ttttggagaa cttgtatgat gtaccacatt cccggcgtgt tatcgccaca
     9721 ggacgtcgcc cggtttcgcg aacaactgga acaagccgaa tgggtggatg gacgcgtcac
     9781 caccggcgca caaggtgcgc aagttaagaa caatcaacag gtcgacaccc gcagcacgtt
     9841 atacgccgcc ctgcaaaatg aggtgctgaa cgcggttaac caacatgctt tattctttgc
     9901 cgcggccttg ccgcgtaccc tttccacgcc gctgtttaat cgctatcaga acaatgaaac
     9961 ctatggtttc catgtggatg gcgcagtacg cagccatcca caaaacggct ggatgcgtac
    10021 tgacctttct gccacgctgt ttttaagcga tccacaaagc tacgacggcg gcgaactggt
    10081 cgttaatgac accttcggac aacatcgggt aaaactcccg gcaggcgatc tcgtgttgta
    10141 tccctccagc agcctgcatt gcgtgacacc cgtaacccgc ggcgtacgag tggcatcatt
    10201 tatgtggatc cagtcgatga tccgcgatga taaaaagcgc gccatgctgt ttgaactgga
    10261 caacaatatt cagtcgctga aaagccgcta cggcgaaagt gaagagatcc tgtcgctgct
    10321 taatctttat cataatctgc tgcgggaatg gtcggagatc tgatgcttga actgcccgag
    10381 ttcgtccctg gattagctac acttaactgt acaagtattg atatggggag gtcgatatgg
    10441 catccggttg ggctaacgat gacgccgtca acgaacagat caacagtaca attgaagatg
    10501 cgatttcccg cgctcggggt gaaattccgc gcggcgaaag cctggatgaa tgtgaagagt
    10561 gcggtgcccc catcccgcag gcccgtcggg aagccattcc tggcgtgcgc ttatgtattc
    10621 attgtcagca ggagaaagat ttacaaaaac cagcttatac aggatataat cgcagaggtt
    10681 cgaaagacag ccagttacgt taactacaac tggcgagatg catagcgagt ataatttgta
    10741 ttttgcgtgg cattccgtgc ctttaacgct gctgtgactg ccacgcggta taaaacaagt
    10801 tcataagtac aacaaataaa tggtttatca gtaggttaga tatcaatcaa tttatttgaa
    10861 caaggcggtc aattctcttc gattttatct ctcgtaaaaa aacgtgatac tcatcacatc
    10921 gacgaaacaa cgtcacttat acaaaaatca cctgcgagag attaattatg aaaactatca
    10981 atactgttgt tgctgctatg gctctttcaa ctctgtcatt tggcgtgttt gccgcggaac
    11041 cggtaacggc atcccaggca cagaacatga ataaaatcgg cgtggtttct gccgatggcg
    11101 catccaccct cgatgccctg gaagcgaaac tggctgagaa agccgcggca gccggtgcca
    11161 gtggatacag catcacttcc gccaccaaca acaataaatt aagcggtact gcggtaattt
    11221 ataagtaatt cgtaggacgg ataaggcgtt tacgccgcat ccggcaacag atgcctgatg
    11281 cgacgctacc gcgtcttatc aggcctacaa aatccgaacc gttggacgga tcaggcgttt
    11341 acgctacgtc cagcacaagt atttccctgt ctgtttgccg acagacgcat atgctctaac
    11401 cctcattgat cctatattac ccttgtttgc ccgtccgtta ctggacgggc tttttttagc
    11461 tggctaactg ctgacagaaa gcctgcaacg tctcttccga cataccaatc tgccgcgccg
    11521 catcacaaat ggcctgccag cttcccgcat ccaatggaat cccctgctcc tgccgttcgc
    11581 gacgcgtgtt cacttcccac tcgcccggta gcaaaatcgg cttatcatca tcatgcggcg
    11641 aggctttcac ccactcggca aaggcttcgg tctgcgcgct acaatccggc gcgccgaaga
    11701 gttccgggtt gatgatgata gtggtcatgc agttaagaat ggcatcggga ctggtttgta
    11761 acgtttcctg atgcgtcgtt ttaccgccgg aaagcgcccc gccaagaatt tcacacatcg
    11821 ctgcaagggc gtagccttta tgttcggcaa aggtcaacag cgaacccaac ggcgactcct
    11881 gcattaccgc cggattggtc gtcggcacgc cgttaacgtc aatcaggcaa cctggcggca
    11941 cggggacgcc tttatgccag gcgacgcggg ttttgccaaa tgcaatggcg ctggtggcgt
    12001 aatcaagcaa cagcgggaaa ttatctttac gagggaaaac cacacagaac ggattggtgc
    12061 caaagcggct gtcgcgaccg tggaacggcg cgaccattgg aataccgacc acgctaacaa
    12121 agtggataga gacaaacccc gccgctgcac actgctccgc ccagtaaccg atacggccga
    12181 tatgatgcga gttatgtagc gccacggcgg caataccgtg ctgatgcgct ttctcaatcc
    12241 ccagcgccat cgcttcatgt gccgcgacct gaccaaatgc gcgatcgcca tcgagcgtga
    12301 ctgccgcccc cgcctcttta acgattttgg catgatggtt aatttgcaga tgcccctgac
    12361 tccaggaacg cacatagctt gggatcatgc caataccatg agaatcatgc cctgccaggt
    12421 ttgccgcgat taaatgatcg gccactaatt tcgcttcttg ttcctcgcta cccatctgac
    12481 gaaatacagc ctgaataaaa ctgtgcagcg tctgagcatc aaagcgatga ccactttcca
    12541 tggttaactc ctgtttatgt tatgtgtttg ttgttttttt atgctgcacg ccgggcgtgg
    12601 gaaggtcaat aaagatgcag gaatttcata ttgcggtggg gtaaaagccg gatgacatgg
    12661 ctcatccggc tgagaaaaga attaaaatgc ctgattaacg cgcgccaggc cgtcgctgat
    12721 agttgccgct tcacccgtag ccaccaggca gcaagccatc tggattttca gcgattcggg
    12781 aatcggttcg ctgccagcaa ggcaacgctc aatccactgc gccgtggttt ccggatcttt
    12841 tgcttgtggc agtaactcgc taccagcagt gtcctgtttt tcatacagca cccgcatccc
    12901 ttcacggtca atgagattga tctgcgggca gcgctgcgga ttagcataca cttcaccttc
    12961 agtaccatgc attagtagcg cccgcccgcc gatatcgcta aagaacttcg cgacgcgtcc
    13021 aatgtattcc ggatgcgaaa cgctggaaag acgcagcgcc tcaccttcgg caaatggcgt
    13081 cgccagtttc gccagggtat gtgcactgtt acgcacgccc atccgccagc gcatcgccag
    13141 ttgtttttcc agcggcgggc aaaacgcgcc gactggcata aacaccggtt gatgttcgtc
    13201 gagcttcgcc tgcgcctgcc cgccgtgcaa cgttggcgta atacccatca attcaaaaat
    13261 ggtttcagtc agcacgcggg ttggatcttc gctaaccccg tgaaccacca caggaaaacc
    13321 gagtttgtgc aggagaatcg ccaacaacgg cgtcaggttg gcctgtttac gcgcgccgtt
    13381 gtaactgggg atgacaatcg gcatcggctt gcctgcaggc ggcgtcagct tgatggtgtg
    13441 attttgcatg gcttcgtaaa agccgagcat ctctgcttcc ccttcccctt tgatacgtag
    13501 cgcaatcaat acgccgccca actcaaggtc agggacttca ccattgagca tatgggcata
    13561 cagaccgcgc gcagtatccc ggtctaaatc gcgcgcgtgg tttttcccgc gcccgatctc
    13621 tttaatgatt ttgcgatagt ccatttacga ctccttacct gactcacatc attaacgccg
    13681 ccgacggcgt ggggatttcg ttttttcttt ctttttaact ataccttcag ggacttccgg
    13741 ttgctctatc ggaaataccg gtaatgcatc cagtagtcgc ttgccataat ttttggtcag
    13801 caagcgtttg tcgtagataa ccacttcgcc ccagcaaccg tggcttcgaa tcagtcgccc
    13861 aacctgctga atcaggttaa acgaggcgct cggcaggctt tgcacctcaa acggatagcg
    13921 gttgaggctt ttcagccatt ccccttcggt gatcaccacc gggctgtcga tgggcggaaa
    13981 agcgattttg tggatatgca cctggctgag cagatcacct ttcaaatcaa gcccttcggc
    14041 aaatgactgt aagcccacca gcacactatg ctcaccgttg gcaacgcgtt tgcggtgcag
    14101 ttcaactaag cgataacgcg gctgatcgcc ctgcaccagc agcatcaggc gtaaatccgt
    14161 cacatagtcg agaaagcgct gcatcgcccg tccgctggca aacagtacca acataccgag
    14221 atgttttttg ctctccacct gctcacggaa aaaggccgcc atttcggcaa tatgctgctc
    14281 ttcgttgtcg atggaaggct caacgcgcat ccggggaata acaattttgc cctgttcgca
    14341 gtggttaaag ggggaatcca gcgccacaaa acggtcgccc gctttctctt tcagcccgct
    14401 catctcctgc aaacgcgaaa aactgttcag cgaacgcaag gttgcggagg tgacaataat
    14461 gtgcggaata ctgcgccaca gcagcctttc cagctgatcg ctgacacgta tccccacgca
    14521 gtgaaaccag agatgcagct gcccttcgcg ctcttcccgc gtcgcccatt tggtcaccgg
    14581 cgcaccggaa gattgcgcca gagacgccag ccgccagagt ttgctttgcg cctcgaacat
    14641 ccccaacgcg cggttcatct gcaaaatcaa ccgatgcaga cgcacaatat cgtggctgcc
    14701 ggttttctca cttaaatcgt taagaaataa ctccgccaga ccacgcagca tctcggtgag
    14761 ttttgccagc cgctggcaga tctccagcac ttcatcaggc agttcgccca tcgcaaaacg
    14821 gtgctctgcc tcctgcccgg caggcatgta gagattgaga atgttgttta acgaggcgat
    14881 aagctcatac aactcttcac aatgcgcatt caaacgttca gggatcgcca gcggtgggat
    14941 ggtcttcggg cgaaactgct ccatgcaggt agcgaccagt ttcgtgaaca agtccagctg
    15001 tagtcgatac cagggcgcgg tgatttcggc actcatctcc agcgcatccc gggccacatc
    15061 tggcaggtga tgaccttcgt ccagcaccag cagcagattt ttcgggtcag gtagtacggc
    15121 ttcgctttcc atcgccgcca tcaccagcgc atggtttgcc accaccactt ccgcttcctg
    15181 aatctcccga cgagcaacaa aaaacgggca ttcacgatag tagtaacagt tgcggttgag
    15241 gcagctggct ttgtcggtac ttaaacgacg ccagagatcg tcatctatag cgatatcagt
    15301 atgatcgcgc agaccatccc atttataagt gtcgagatcg cccttcagct tcgcacaacg
    15361 tttttgctct tcctgattat ttggcgtcag ttcgtcgtca agaaacgcca gcagatcctg
    15421 ttgcgtgggc tcagtgctgg cgagcgccgt cagattacgc gggcaaacgt agcgcccacg
    15481 cccaaaagcg gcagtgaatt taagatcggg aatgatcttt ttcagcagcg gtaaatcttt
    15541 gctgtaaatc tgatcctgca acgccacgtt ggcggtactc accaccagcg ttttttgctc
    15601 ttcgcgggca atggcgatgc cggggatcaa ataggagagc gttttcccaa cgccggtggg
    15661 ggcttcaatc gccagatgcc gcccttcttc tccggccagc gttttggcga cgtccgcaat
    15721 catctgccgc tgcggcgcac ggggaataaa gtcggggatc tgttcctgaa gcgccttata
    15781 ccaggcggca atttgcgctt taagcgcggc ggttaatgcc atgagaaaac ctgaaatact
    15841 gtataaacag ccaatattgt ggcatttttc ggttttcagg ggtaatggtt tttctgtttc
    15901 tggaaagcgg ctcgcaataa ccaccaacat aatgcggttt aatgcccgtt cgagcacaaa
    15961 ggatccaaca cgtcatgcaa gacaccatca taaatttcta cagcaccagc gatgactacg
    16021 gtgatttttc taactttgcc gcctggccca tcaaggttga cgggaaaacc tggcccacct
    16081 cagaacacta ttttcaggca caaaaattcc ttgatgaaaa ataccgcgaa gagatccgtc
    16141 gggtttcttc ccctatggtc gccgcacgca tggggcgcga tcgttctaag cctctgcgta
    16201 aaaactggga gtcggtcaaa gaacaggtga tgcgaaaagc acttcgcgct aaattcgaac
    16261 agcatccaga actgcgtgcg ctcttgctgg caaccgcgcc cgcaaaactg gttgagcata
    16321 cggaaaacga tgcttactgg ggagacggtg gtaatggtaa gggcaagaat cgactgggct
    16381 accttttaat ggagttgcgc gaacaattgg ctatagagaa gtaacgtctc ggtggcttat
    16441 gggcggtaaa acagataaat tttttcccgt gttctcaaat tgctgacaag tgcttgttgt
    16501 gaaatgccgg atgcggcgta aacgccttat ccggcctaca aaagcatgca aattcaatat
    16561 attgcagagt tcacgtaggc ctgataagcg tagcgcatca ggcagttttg cgtttgttca
    16621 tcagcctgat gccgggcata gcccggcata aaagattact gcgcagcggt aggtttacgc
    16681 ggacggcggc gacgttgttg ttcgcctgcc ggtttggcat cgccgaggcg gcgagacggt
    16741 ttttctgcag gtttcgcgct tgcagatttt gcgccacctt ccccacggcg tggttgctgt
    16801 tgaccgcgac caccaccttg cccacgaccg ccgccacgtt gctggcgacc gttctggatc
    16861 ggttcggctt tgattgacgg gtccggctca tagcccggaa tcgcaatgcg cgggatctct
    16921 tttttcagca gtttttcgat atcacgcagc agtttgtgtt catcaacaca caccaacgac
    16981 aacgcttctc cggtggctgc ggcacgaccg gtacgcccga tacggtggac ataatcttcc
    17041 ggtacgtttg gcagttcata gttgacgacg tgcggcaact cttcgatatc cagaccgcgc
    17101 gcagcgatgt cagttgccac cagtacgcga atgtcacccg atttaaaatc ggccagcgca
    17161 cgggtacgcg caccttgcga tttattaccg tggatcgccg cactgcggat gccatcttta
    17221 ttgagctgtt cagccagatg gttagcgcca tgtttggtac gggtaaacac cagcacctgc
    17281 tgccagttcc ctttgccaat catgtgcgac aacagttccc gtttacgttt cttatcgaca
    17341 aagtgaacgt gctgtgtcac ctgatcagac gcggtattgc ggcgtgccac ttcgatttcc
    17401 agcgggttgt gcaacagttt ttccgccagg gctttaatat cgtcagagaa ggtcgcagag
    17461 aacagcaggt tctggcgttt cgctggcagt tttgttaaca cgcgacggat atcgtggata
    17521 aagcccatgt cgagcatgcg gtcagcttca tcgaggacga ggatttcaac ctgatccagc
    17581 ttcactgcat tttgatgttc caggtccagc aaacgtcccg gtgttgccac cagaacatca
    17641 acgccgccgc gcagcttcat catttgcggg ttaatgctga caccgccaaa caccaccagc
    17701 gaacgaatgt tcaaatattt gctgtaatca cggacgtttt cgccaatctg cgcagccagt
    17761 tcacgggtcg gggtaagaat gagcgcacgt accggacgac gccctttggc gtgcggctgg
    17821 cgagtgatca ggtgttgcaa cagcggcagc gtaaagcccg ctgttttacc ggtaccggtc
    17881 tgggcgctag ccatcaggtc gcggccttcc agcaccgcag ggatcgcctg ctgctgaata
    17941 ggggtgggtt cacggtaacc ctgctcggca acggcgcgca ggatatcagg gcttaaaccc
    18001 aaagaatcga aagacataac tactccgaac cgccccgacc gttaccggtg tagttttcag
    18061 ggagatactg aaaaggaaaa tgacaaaaac cacaatgtca tgagggagcg gagtgtagca
    18121 gtttttgtga cacagcgcat aaattatccc tgtgactggc gtagccaaaa ttcttagcca
    18181 tactggacaa ctcccctatg gagtcataat cttaatcaat catttgatta agaatggact
    18241 gtgcgatgaa taatcctgcc atgacaatca agggtgaaca ggcgaaaaaa cagctgattg
    18301 ctgccgcact ggcgcagttt ggtgaatatg gaatgaacgc caccacccgc gagatagccg
    18361 cccaggccgg gcagaatatc gctgccatca cctattactt cggttcgaaa gaagatttgt
    18421 acctcgcctg cgcccaatgg attgccgatt tcattggcga gcagtttcgt ccgcacgccg
    18481 aagaagccga atgcttgttc gcacaaccac agcctgatcg cgcagctatc cgtgaactga
    18541 tccttcgcgc ctgcaggaac atgattaagc tgctcaccca ggatgacacc gtcaacctca
    18601 gcaagtttat ctcccgtgag cagctctctc ccacggcagc ctaccacctg gtgcacgaac
    18661 aggtgattag tccgctacac agccacctga cacgcctgat tgccgcctgg accggctgcg
    18721 acgccaacga tacccgcatg atccttcaca cccatgcgtt gattggtgag attctggcgt
    18781 tccgtcttgg caaagaaacc attttgttac gtaccggctg gaccgcgttc gatgaagaaa
    18841 agaccgaact gatcaaccag acggtgacct gtcatatcga cctgattttg caaggattat
    18901 cgcaaaggag tttgtagtga tgaaaaaacc tgtcgtgatc ggactggcgg tagtggtact
    18961 tgccgccgtg gttgccggag gctactggtg gtatcaaagc cgccaggata acggcctgac
    19021 gctgtatggc aacgtggata ttcgtacggt gaatcttagt ttccgtgttg gggggcgcgt
    19081 tgaatcgctg gcggtggacg aaggtgatgc tatcaaagcg ggccaggtgc tgggcgaact
    19141 ggatcacaag ccgtatgaga ttgccctgat gcaggcgaaa gcgggcgtct cggtggcaca
    19201 ggcgcagtat gacctgatgc ttgccgggta tcgcgatgaa gaaatcgctc aggccgccgc
    19261 tgcggtgaaa caggcgcaag ccgcctatga ctatgcgcag aacttctata accgccagca
    19321 agggttgtgg aaaagccgca ctatttcggc aaatgacctg gaaaatgccc gctcctcgcg
    19381 cgaccaggcg caggcaacgc tgaaatcagc acaggataaa ttgcgtcagt accgttccgg
    19441 taaccgtgaa caggacatcg ctcaggcgaa agccagcctc gaacaggcgc aggcgcaact
    19501 ggcgcaggcg gagctgaatt tacaagactc aacgttgata gcaccgtctg atggcacgct
    19561 gttaacgcgc gcggtggagc caggcacggt tctcaatgaa ggtggcacgg tgtttaccgt
    19621 ttcactaacg cgtccggtgt gggtgcgcgc ttatgttgat gaacggaatc ttgaccaggc
    19681 ccagccgggg cgcaaagtgc tgctttatac cgatggtcgc ccggacaagc cctatcacgg
    19741 gcagattggt ttcgtttcgc cgactgctga atttaccccg aaaaccgtcg aaacgccgga
    19801 tctgcgtacc gacctcgtct atcgcctgcg tattgtggtg accgacgccg atgatgcgtt
    19861 acgccaggga atgccagtga cggtacaatt cggtgacgag gcaggacatg aatgatgccg
    19921 ttatcacgct gaacggcctg gaaaaacgct ttccgggcat ggacaagccc gccgtcgcgc
    19981 cgctcgactg taccattcac gccggttatg tgacggggct ggtggggccg gatggtgcag
    20041 gtaaaaccac gctaatgcgg atgctggcgg gattactgaa acccgacagc ggcaatgcca
    20101 cggtgattgg ctttgatccg atcaaaaacg acggcgcgct gcacgccgtg ctcggctata
    20161 tgccgcagaa atttggtctg tatgaagatc tgacggtgat ggagaacctc aatctgtacg
    20221 cggatttgcg cagcgtcacc ggcgaggcac gtaagcaaac ttttgctcgc ctgctggagt
    20281 ttacatctct tggcccgttt accggacgcc tggcgggcaa gctctccggt gggatgaaac
    20341 aaaaactcgg cctggcctgt accctggtgg gcgaaccgaa agtgttgctg ctcgatgaac
    20401 ccggcgtcgg cgttgaccct atctcacggc gcgaactgtg gcagatggtg catgagctgg
    20461 cgggcgaagg gatgttaatc ctctggagta cctcgtatct cgacgaagcc gagcagtgcc
    20521 gtgacgtgtt actgatgaac gaaggcgagt tgctgtatca gggagaacca aaagccctga
    20581 cacaaaccat ggccggacgc agctttctga tgaccagtcc acacgagggc aaccgcaaac
    20641 tgttgcaacg cgccttgaaa ctgccgcagg tcagcgacgg catgattcag gggaaatcgg
    20701 tacgtctgat cctcaaaaaa gaggccacac cagacgatat tcgccatgcc gacgggatgc
    20761 cggaaatcaa catcaacgaa actacgccgc gttttgaaga tgcgtttatt gatttgctgg
    20821 gcggtgccgg aacctcagaa tcgccgctgg gtgcaatatt gcatacggta gaaggcacac
    20881 ccggcgagac ggtgatcgaa gcgaaagaac tgaccaagaa atttggtgat tttgccgcca
    20941 ccgatcacgt caactttgcc gttaaacgtg gggagatttt tggtttgctg gggccaaacg
    21001 gcgcgggtaa atcgaccacc tttaagatga tgtgcggttt gctggtgccg acctctggcc
    21061 aggcgctggt gctggggatg gatctgaaag agagttccgg taaagcgcgc cagcatctcg
    21121 gctatatggc gcaaaaattt tcgctctacg gcaacctgac ggtcgaacag aatttacgct
    21181 ttttctctgg tgtgtatggc ttacgcggtc gggcgcagaa cgaaaaaatc tcccgtatga
    21241 gcgaggcatt tggcctgaaa agtattgcct cacacgccac cgatgaactg ccattaggtt
    21301 ttaaacagcg gctggcgctg gcctgttcgc tgatgcatga accggacatt ctgtttctcg
    21361 acgaaccgac gtccggcgtt gatcctctca cccgccgtga attttggcta catatcaaca
    21421 gcatggtaga gaaaggcgtc acggtgatgg tcaccaccca ctttatggat gaagcggaat
    21481 attgcgaccg cattggcctg gtgtaccgtg ggaaattaat cgccagcggc acgccggacg
    21541 atttgaaagc acagtcggct aacgatgagc aacccgatcc caccatggag caagccttta
    21601 ttcagttgat ccacgactgg gataaggagc atagcaatga gtaacccgat cctttcctgg
    21661 cgtcgcgtgc gggcgctgtg cgtcaaagag acgcggcaga tcgttcgcga tccgagtagc
    21721 tggctgattg cggtagtgat cccgctgttg ctgctgttta tttttggtta cggcattaac
    21781 ctcgactcca gcaagctgcg ggtcgggatt ttactggaac agcgtagcga agcggcgctg
    21841 gatttcaccc acactatgac cggttcgccc tacatcgacg ccaccatcag cgataaccgt
    21901 caggaactga tcgccaaaat gcaggcgggg aaaattcgcg gtctggtggt tattccggtg
    21961 gatttcgccg aacagatgga gcgcgccaac gccaccgcac cgattcaggt gatcaccgac
    22021 ggcagtgagc cgaataccgc taactttgtg caggggtatg tcgaagggat ctggcagatc
    22081 tggcaaatgc agcgagcgga ggacaacggg cagacttttg aaccgcttat tgatgtacaa
    22141 acccgctact ggtttaaccc ggcggcgatt agccagcact tcattatccc cggtgcggtg
    22201 accatcatca tgacggtcat cggcgcgatt ctcacctcgc tggtggtggc gcgagaatgg
    22261 gaacgcggca ccatggaggc tctgctctct acggagatta cccgcacgga gctgctgctg
    22321 tgtaagctga tcccctatta ctttctcggg atgctggcga tgctgctgtg tatgctggtg
    22381 tcggtgttta ttctcggcgt gccgtatcgc gggtcgctgc tgattctgtt ttttatctcc
    22441 agcctgtttt tactcagtac cctggggatg gggctgctga tttccacgat tacccgcaac
    22501 cagttcaatg ccgctcaggt cgccctgaac gccgcgttcc tgccgtcgat tatgctctct
    22561 ggctttattt ttcagatcga cagtatgccc gcggtgatcc gcgcggtgac gtacattatt
    22621 cccgctcgtt atttcgtcag caccctgcaa agcctgttcc tcgccgggaa tattccagtg
    22681 gtgctggtgg taaacgtgct gtttttgatc gcttcggcgg tgatgtttat cggcctgacg
    22741 tggctgaaaa ccaaacgtcg gctggattag ggagaagagc atgtttcatc gcttatggac
    22801 gttaatccgc aaagagttgc agtcgctgct gcgcgaaccg caaacccgcg cgattctgat
    22861 tttacctgtg cttattcagg tgattctgtt cccgttcgcc gccacgctgg aagtgactaa
    22921 cgccaccatc gccatctacg atgaagataa cggcgagcat tcggtggagc tgacccaacg
    22981 ttttgcccgc gccagcgcct ttactcatgt gctgctgctg aaaagcccac aggagatccg
    23041 cccaaccatc gacacacaaa aggcgttact actggtgcgt ttcccggctg acttctcgcg
    23101 caaactggat accttccaga ccgcgccgtt gcagttgatc ctcgacgggc gtaactccaa
    23161 cagtgcgcaa attgccgcca actacctgca acagatcgtc aaaaattatc agcaggagct
    23221 gctggaagga aaaccgaaac ctaacaacag cgagctggtg gtacgcaact ggtataaccc
    23281 gaatcttgac tacaaatggt ttgtggtgcc gtcgctgatc gccatgatca ccactatcgg
    23341 cgtaatgatc gtcacttcac tttccgtcgc ccgcgaacgt gaacaaggta cgctcgatca
    23401 gctactggtt tcgccgctca ccacctggca gatcttcatc ggcaaagccg taccggcgtt
    23461 aattgtcgcc accttccagg ccaccattgt gctggcgatt ggtatctggg cgtatcaaat
    23521 ccccttcgcc ggatcgctgg cgctgttcta ctttacgatg gtgatttacg gtttatcgct
    23581 ggtgggattc ggtctgttga tttcatcact ctgctcgaca caacagcagg cgtttatcgg
    23641 cgtgtttgtt tttatgatgc ccgccattct cctttccggt tacgtttctc cggtggaaaa
    23701 catgccagta tggctgcaaa acctgacgtg gattaaccct attcgccact ttacggacat
    23761 taccaagcag atttatttga aggatgcgag tctggatatt gtgtggaata gtttgtggcc
    23821 gctactggtg ataacggcca cgacagggtc agcggcgtac gcgatgttta gacgtaaggt
    23881 gatgtaactt cttatctttc gccagcaaag acactaccgc cgggccggca aggattgcca
    23941 gccctgcaat tgccagcaaa aagttgtttt ccagtacacg ggacaacagc cacagcacaa
    24001 tcagcgctgc gccaaaatac caggtcgtgg tcagctcttc cagcacgtct gccacctcac
    24061 gccagcgttg ctcggggtgg cgctgaaaca ccaacatcat cactaccgtg acacaataca
    24121 gtgcgcataa tcccacgccg acgtgaacca gagtcttact catccagccc accaccagca
    24181 gcgccactac cagtaaatgc aacataatct gccagcaact tagaccagtt gcgacacgaa
    24241 cacgttgttg ccacttcatg gcttctctcc tgaagaattt atctctactt actcagagta
    24301 ccgaacttta cggaaaattc cgtaagaccg cacctttttg tgacgccgac tacactattt
    24361 caatgagata agaggcaaag acaggaaaat tatgcccgat caaacacaac aattttcgtt
    24421 caaggtgctc accatcaaca ttcacaaagg ttttaccgcg tttaaccgac gcttcatttt
    24481 gccggaactt cgcgacgcgg tgcgtaccgt cagcgccgat attgtttgcc tgcaggaagt
    24541 gatgggcgcg cacgaagttc atccgctgca tgtggaaaac tggcccgata cctcgcacta
    24601 cgagtttctc gccgacacga tgtggagcga ttttgcctac ggtcgcaatg ccgtataccc
    24661 ggaagggcat cacggcaacg ccgtactgtc gcgttatccc attgaacatt atgagaatcg
    24721 cgatgtttcg gtcgatggtg cggaaaagcg cggcgtgctc tactgccgca ttgtgccacc
    24781 gatgaccgga aaagcgattc atgtgatgtg cgtacatctg ggcctgcgtg aggcgcaccg
    24841 tcaggcgcag cttgcgatgc tcgccgaatg ggtgaatgag ctaccggacg gcgaaccggt
    24901 attggtggcg ggtgatttca atgactggcg gcaaaaagct aatcatccgt taaaagtgca
    24961 ggccggactg gatgagattt ttacccgcgt ccacggacgc ccggcgcgca cgtttccggt
    25021 gcaatttcct ctactacgac tggacaggat ctacgtcaaa aatgccagcg ccagcgcgcc
    25081 aaccgcgttg ccgctgcgga catggcgaca cctttctgat catgcccctt taagtgcgga
    25141 gattcattta tgaaatgtag ctggcgcgaa ggcaataaga tccagttgct ggaaaacggc
    25201 gagcaatatt atcccgcggt gtttaaggcg attggcgagg cacaagaacg catcattctt
    25261 gaaacgttta tctggtttga ggatgacgtc ggcaaacagc tgcatgcggc actactggca
    25321 gcagcgcaac gcggggttaa agcggaagtc ttgctggatg gctacggttc gccggatctc
    25381 agcgatgagt ttgtcaatga actgacggca gctggcgtgg tatttcgcta ctacgatccc
    25441 cgccctcgcc tttttggtat gcgcaccaat gtgtttcgcc ggatgcatcg caaaattgtg
    25501 gtgatcgacg cgcgtatcgc ctttattggc gggctgaatt actccgccga gcatatgtcc
    25561 agctacggtc cagaggctaa acaggattac gcggtacgcc ttgaagggcc gattgtcgaa
    25621 gatattctcc agtttgagct ggaaaacctg cctggacaga gcgcggcacg acgctggtgg
    25681 cgacgtcatc acaaagcgga agagaaccgc cagccgggag aagcgcaggt attgctggtc
    25741 tggcgcgata acgaagaaca tcgcgatgat attgaacgtc actatctgaa aatgctcact
    25801 caggcgcggc gagaagtcat tatcgccaac gcctacttct tccccggcta tcgattttta
    25861 cacgccttgc gtaaagcggc acggcgcggg gtgcggatca aactgatcat tcagggcgaa
    25921 ccggatatgc cgattgtcag agtcggtgcg cgcttgctgt ataactatct ggttaaaggc
    25981 ggcgttcagg tatttgagta ccgccgccgc ccgctccacg gcaaagtggc attgatggac
    26041 gatcactggg cgacagtagg gtccagtaat ctcgatccgc tcagtttgtc actgaatctc
    26101 gaagcaaatg tcatcatcca cgatcgtcat tttaaccaga cgctgcgcga taatctgaac
    26161 ggcattattg ccgcagattg tcagcaggtc gatgagacca tgctgccgaa acgcacctgg
    26221 tggaacctga ccaaaagcgt gctggcgttc cactttttac gccacttccc ggcgctggtt
    26281 ggctggcttc cggcacacac accacgtctg gcgcaggttg atccgcccgc acaaccgaca
    26341 atggaaacgc aggatcgggt agaaactgaa aacacggggg taaaaccctg atgagtaaat
    26401 cacacccgcg ctggcgctta gcaaagaaga tcctcacctg gctgtttttt atcgcggtga
    26461 ttgtgttgct ggtggtctac gccaaaaaag tggactggga agaggtctgg aaggtcatcc
    26521 gcgactacaa tcgcgttgcg ctgcttagtg cggtcgggct ggtggtcgtc agctatctga
    26581 tttacggctg ctatgacctg ctcgcccgct tttactgcgg tcacaaactg gcgaagcgcc
    26641 aggtgatgct ggtgtcgttt atctgctacg ccttcaacct gacgctcagt acctgggtcg
    26701 gcggcattgg tatgcgctat cgtttgtact cccgactagg gttaccgggc agcactatta
    26761 cgcggatttt ctcgctcagt attaccacca actggctggg ctatatttta ctggcaggga
    26821 ttatctttac cgcaggcgtg gtggagttgc cggatcactg gtatgtcgat caaactacgc
    26881 tgcgtattct cggcattggc ttactgatga ttatcgcggt ttatttgtgg ttttgcgctt
    26941 tcgcgaagca ccgccatatg accatcaaag ggcaaaagct ggtgctgcct tcatggaaat
    27001 tcgccctcgc tcagatgctg atttccagcg ttaactggat ggtaatgggg gcgattatct
    27061 ggctgttact tggtcaaagc gtgaactatt tctttgtact gggcgtgtta ctggttagta
    27121 gtattgctgg cgtcatcgtg catattccgg cggggatcgg tgtgctggaa gcggtgttta
    27181 tcgcactact ggctggggag catacctcga aagggagcat tatcgccgcc ctgctcgctt
    27241 atcgcgtcct gtattacttt atcccgctgc tgctggcgct gatctgttac ctgctactgg
    27301 aaagccaggc gaagaagcta cgggcgaaaa atgaagcggc gatgtgaagt ttagttaagt
    27361 tctttagtat ctgcatttac gactaatgaa aaaaacgcgt atgcctttgc cagacaagcg
    27421 ttatagctat cgcggcaagt atcccaaaga agccgataaa atagtaatag agtgttaatg
    27481 cacctgtaac agcgcaacga accggactcc acaactcttc actatggcat ttccccgcca
    27541 attcaaggag cttatttcgt ccatgcgaga taatgcctga ccataacaca atcattaagc
    27601 aacttattac ccaaacgggt cgttcactca ttaatgcggc attcatgatg atcaccaggg
    27661 ccaaccctgt caacgtcatc ataatgataa aacggtgaga accaggatca acattaaata
    27721 ataaaccggc cagcatactg attaaaaaca tcgcgcccgc agtgctgaac acgacgataa
    27781 tggcaggtac aggagctaaa cttgcaacga caatcgccac caaagagagt aaaaacagat
    27841 atattacgcc tgcgatgacg gcatttatct tgttgatatc cttacttaag ccatacatac
    27901 aaactaataa taaccctatg gcgacataca ttgttggtga atcatatttg gttgccgtaa
    27961 tttcgagata cttagctccc caggccagtc ctgcggttgc caccaaacct aaagcggtaa
    28021 tgagccatat gctgtttaat atcctggctt cgtgctgaaa atcattagtt atgttatttg
    28081 ctgagcgcga attcattatt tttatatcct taagttaaat atcattatct attccaatta
    28141 acgcaataaa actcgtcaat tcgcactacc acactaaacc attaataaat tcaagaactg
    28201 ttacagtaat tctaaagagg acgcttaaaa tactaaaata gagtgttatt gccccaggaa
    28261 cgatacagcg aagagaacct gaaatttcag aggtgtcggc aacacggatc aaatcttcca
    28321 gtgttgttgc ttcacaggca gccgtaatgc cccagataaa gacagtcaaa atactcgcta
    28381 accacacgga aaaactgctg gtaaggatca ggttaacaac aaaagcaata ctcaaaccac
    28441 agaaaatata tgaatataac tgtctgactg gtgggataac cctattacta caagagcaaa
    28501 tcagcgccat tgcggcaaac atccctcccg taattcccat taccgtcgct atgctcgaaa
    28561 aggtataaag gctggcgaag agaaagccaa caagaaggat tattagcaga tagaccagac
    28621 atgcgcctga tacattcagt cttttcaggg cgttgtttaa ccagagacca cctattatca
    28681 gcgcagccaa agcgaagaca aacgcacctg gagacttttg tgacgtaacc caatgcaaat
    28741 gctgaaatat ccaggcacag cctgccgtag cccatactcc agctgctgtt aaccaccaaa
    28801 tgagaagcag cattttgctg agcgaagcac ttttttgctg taattgagta gcagtggatt
    28861 gtctgttcaa atgcgttatc tgtccctgaa attacgtagt ggacatagtc tggcatttgc
    28921 cgcgattcag ttctcatgta aatgagcgga atagtcttta taaaatccga aaaaaatccc
    28981 ggctccaggc cgggatcagc aggaagaaga gaatttaacg gcggttgccg aagatccgca
    29041 acaacatcag gaacaggttg atgaagtcca gatacaaggt taacgcgcca agaatggaat
    29101 atttgcgcag gttcgacgtg tcgcgggtat caatctgctc acccatattt ttcagtttct
    29161 gcgtgtcata cgccgtcaat ccgacaaaga caatcacgcc gatgtaggta actgcccaca
    29221 tcaatgcttc gcttttcaac cagaagttga ccagcgatgc cagcacaatg ccgattaacg
    29281 ccataaacag catattgcca aagccactta aatcgcgctt cgtggtgtaa ccgtacaggc
    29341 tcattgcgcc gaacatcccg gcagtaacga cgaaagtact ggcgatagaa gcagcggtat
    29401 agacaatgaa tatactggaa agcgtaagac ccgtcagcgc cgaataaagc ataaagagca
    29461 tcgtcgttac acctgcgctc agcttttgaa tcatcgctga taacacaata accaatgcta
    29521 attgcgcgat gatcagaccg attaaaaaga cacggttagt gaacaacagc tccatcacgg
    29581 ccgcggaatt agccgcatac caggcaacaa atgcggtcag caacaagcca acggtcatcc
    29641 aaccatagac ttgcgccata taagtttgca agccagcccg gggttgtacg attgaatcag
    29701 aacgtgggaa tctgtccatg acgatctcct gaagatataa ggaatatctt aaggatactg
    29761 caaaatgatg aggctgtgca tcgacgcagc gtaaacgtat gtactgagcg gtgaaattgc
    29821 cggacgcagc ggtgccttat ccggctaaca aaaaactacc agcgttttgc cgcctgctga
    29881 tcgctctccc gggcttcaac ccagcggtcg ccttccggcg tggcttcgcg cttccagaac
    29941 ggtgcgcggg ttttgagata atccataata aactgcccgg cttcaaacgc actgctgcga
    30001 tgcgcactgg tgacaccgac aaaaacgatt tcatcgcccg gccataattc cccgatgcgg
    30061 tgaatcacag tgacgcgccc cagcggccag cggttacgcg cttcatcaac aatttctgcc
    30121 agtgcttttt cagtcatccc cggatagtgt tcgagggtta atgctttgac gctgtcgccc
    30181 aggttatggt tgcgcacctt accagtaaag gtgactaccg caccgtcttc gtcacgctcc
    30241 gccagccacg ggtactcttc tcctacgctg aacggctgcg gaccaacaac aattttggtt
    30301 tctgccatct taacctccgg ttaccggcgg gaagaaagct acttcgtcgc cgtcagtcag
    30361 cggatggtca aaactcacca gcgtctggtt gacggcagcc agtaatttgc catcttccag
    30421 cgccagcgcc cagcgatcgc tctgcgcagc catgtgctgg cgtaacgctt caacagttgg
    30481 gaaatccgca gccacttcgg ttgcatctgt tcccaccaac tcgcgcacct gggcgaaaaa
    30541 aagaacttta atcatccgct tccaccttaa agtcacccga cttgccgccg ctcttcgcca
    30601 gcaaacgtac cggaccaatc accatatctt tttgcaccgc tttgcacatg tcataaatgg
    30661 tcagcgccgc cacggaggcc gcggttaatg cttccatttc gacaccggtt ttcccggtca
    30721 ggcggcataa ggtttctata cgcacccgat tgtgctccgg ctcggcctgt aaattgactt
    30781 caactttgct gagcatcagc ggatgacaga gcgggatcag atcccaggtg cgttttgccg
    30841 cctgaatacc ggcaatacgc gcagtggcaa atacgtcgcc tttgtggtgg cgaccatcaa
    30901 taatcatcgc cagcgtctcg ctgcgcatgg tgacaaaggc ttccgcccgc gcttcacgca
    30961 cggtttccgc tttggcggag acatccacca tgtgcgcttc gccagcggcg ttgatatggg
    31021 tcagttgcga catacttatt tcttcaaatg tggatggaaa ttacacggac gcgtacgggc
    31081 atccagctgc ggcgcgatga tattttccca tgcggtacgg cacgctttgg tcgaacccgg
    31141 catggcgaaa atcagcgttt tgttggcgac gcccgctacc gcacgagatt gcaacgtgga
    31201 agtgccaatc tcttcaaaag acaacatccg gaacacttca ccaaaacctt caacttcacg
    31261 gtcgaacaac ggcagcaatg cttcgggagc ctgatcacct tccgtcaggc cagtaccacc
    31321 cgtaatcaat accacttgta catcgtcgct ggcgatccac gcagatacct gagcgcgaat
    31381 agcgtagcgg ttttctttca caatggcttt atcgacaacg tgatggcccg cttcttgcgc
    31441 cgaatcgcgc agatagtgac cggaggtatc gtcttcttca ccgcgacgat tagaaaccgt
    31501 aagaatagca atacgggtcg ggataaattc agtgcttacc tgactcatct gatctctcct
    31561 tttgacgttt tagccgccaa tgtacgataa gttttgcgta ataccggtgt tgttttgatg
    31621 caggaaatgg gtctgtttct tctcccgcag cgccgctgaa atacgcgctt ccagcgcctg
    31681 ttgctgggta tcgtcttcca gcagatcgcg caggttaacg ccgccttcac caaacaggca
    31741 gagatggagt ttaccaatgg aggaaacgcg caggcggttg caagtggcgc agaagtcttt
    31801 ttcatacggc atgataaggc caatctctcc ggcgtaatct ggatggcaaa agacttgcgc
    31861 gggaccgtcg ctgcgttgac gtaattggtg gatccagccg cgacgcagta gctcgtcacg
    31921 cagaacctga ccagagatgt gatgcttacg gaagagctcg ctgccctcgc ccgtttccat
    31981 cagttcgatg aaacgcagct ggatagggcg atgctggatc cagttcagaa aggtgtcgag
    32041 ctggtgatga ttaacatcac gcatcagcac ggtattgact ttgaccttct caaaaccgac
    32101 ctcaaatgca gcatcaatcc ccgccatgac ctggttgaat ttatcctgcc cggtaatagc
    32161 gtgaaactgg cgggcgtcca gactgtcgac actgacgtta atgccagtaa gtcccgcatc
    32221 gcgccagttc gccacatcgc gttccagacg gtaaccattg gtggtgaccg caatctggcg
    32281 gatagcgtcg ttttcccgca cagcggcgat gatatcggta aagtcgcggc gtaaagacgg
    32341 ctcaccgcct gtcaggcgca ctttttcggt gcccagactg gcgaaggcgc gcgtaacccg
    32401 gcgaatttca tcgacggtaa gaaagccttt attggtgacg ccgctcggtt tgtagccatc
    32461 cggcaggcag taggtgcaac gaaagttaca cacatcggta atcgacaggc gcaagtagta
    32521 aaacttacgc gcaaatgcat cagtcagttg tgaagccatg tacacctttc cagatacggg
    32581 aggcgaagtc atttcttcct tcgccctggt ggcaatcttt acgagcattg tcacggccaa
    32641 agcaccgtat cagttgaccc aggtgcagag gctagagtgt ttagtggtta tgccgatact
    32701 agcgtgtaaa tgagattttt accatccaca ctttcgctat gtaatcatgt atatagcgtc
    32761 atgatcgtgc tatttcgcta cagaataagg gaaaatggcg gttttacttt gatatacatc
    32821 atcagggagg catagcgtgc atcgtccttt agaggtagaa gaaaatagtt tgtatcctca
    32881 atattggcag gttaattgct gtttccccgc aatttgcgct actgtagcgc ggataatctg
    32941 actccaggaa actatatgcg caatcgtacg ctggctgatc ttgatcgtgt cgttgctctc
    33001 ggcggagggc atggactggg acgcgttctc tcatcacttt cgtctttggg ttctcgttta
    33061 acgggtatcg tcaccaccac cgataatggt ggctcgacgg ggcgtattcg ccgttcagaa
    33121 ggcggcattg cctggggcga tatgcgcaac tgcctcaacc agctgataac ggaaccgagc
    33181 gtcgcctccg cgatgtttga ataccgtttt ggtggcaatg gcgaactttc cggtcataat
    33241 ctcggaaact tgatgttaaa ggcgctggat caccttagcg tgcggcctct ggaagccatc
    33301 aatttaattc gtaatctgct gaaagtggat acgcatttga ttccaatgtc agagcatcct
    33361 gttgatctga tggcgattga cgatcagggg catgaagttt acggcgaggt caatatcgac
    33421 cagttaacta cgccgattca agagttattg ttaacgccta atgtacccgc aacgcgtgag
    33481 gcggttcacg ctatcaatga agcggatctc atcattattg ggcctggcag tttttatacc
    33541 agcctgatgc caattctgct gctgaaggaa atcgcccagg cattacgccg cacgccagcg
    33601 ccgatggttt atatcggcaa tctggggcgt gagttgagtt tacctgcggc taatttgaag
    33661 ctggaaagca agctggcaat tatggagcag tatgttggta aaaaggtcat tgatgcggtc
    33721 atcgtcgggc caaaagtgga tgtctcggcg gtgaaagagc ggattgtaat ccaggaggta
    33781 ctggaggcca gcgatattcc gtatcgtcat gaccgccagt tgttacataa cgcgctggaa
    33841 aaggcgttac aggctttagg ttaacggaaa tccgaaggaa aattccggct tcctattgaa
    33901 gacaaagtgc gcgttgttta tgccggatgc ggcgtgaacg ccttatccgg cctacaaacc
    33961 gcgcaaattc aatatattgc ggagaaaatg taggcctgat aagcgtagcg catcaggctg
    34021 ttttccgttt gtcatcagtc ttcttcgcta tcctgttacg atgccgcgat aaacagctca
    34081 cgcagctgat gcaactggtc acgaatttgc gccgcttctt cgaactccag attctgcgcg
    34141 tgttgcatca tcaacccttc cagctcatgg attttctgct gcaacgcttt aggcgacata
    34201 tccatcggca cattatccgg ctcaacaatc ggtcgcgatt ttcctctgcc cttcgctttg
    34261 gttttagcaa tgttctgccc caacgccagg atatcgacca ctttcttgtt caagccttgc
    34321 ggcgtaatgc cgtgttcctc gttgtacttc tgctgtttct cgcggcgacg ttcggtttcg
    34381 ccaatcgctt tcgccattga tggggtgatc ttatcgccgt agagaatcgc tttaccgtta
    34441 acgttacgtg ccgcacgacc aatggtctgg atcaacgaac gttcggaacg caggaagcct
    34501 tctttgtcag cgtcgaggat cgccaccagc gaaacttccg gcatatccag accttcacgc
    34561 agtaagttga tccctaccaa tacgtcgaac tcacccagac gcaagtcgcg gataatctcc
    34621 atacgttcga cggtgtcgat atctgagtga agataacgca cgcgctcgcc atgttcttcg
    34681 agatattcgg taagatcttc cgccatccgc ttggtcagtg tggtgaccag tacgcgttcg
    34741 ttaattgccg ctcgctgacg aatctccgaa agaagatcat caacctgtgt cgccaccggc
    34801 cgcacttcga taatcgggtc aagcaatccg gttggacgca ccacctgatc caccacatcg
    34861 ccgccggatt tttccagctc gtaattaccc ggcgtcgccg aaacatagat ggtttgcggc
    34921 gctaatgctt cgaactcttc aaacttaagc ggacggttat ccagcgctga tggcaggcgg
    34981 aagccgtact ccaccagtgt ctctttacgc gcccggtcac cgcgatacat gccgccaatt
    35041 tgtggaatgg tgacgtgaga ttcatcgacc accagcagcc catcagcagg gaggtaatca
    35101 aacagcgtcg gcggtggctc acccggtcca cgaccggaga ggaagcgcga gtagttttca
    35161 atccccgaac agtagcccag ctcgttcatc atctccagat caaactgggt acgctgggtc
    35221 agccgctgct cttccagcag tttgttgttt tccaacagca ctttgcgtct ggcggccagc
    35281 tcttctttga tctcctccat cgcctgtacg atgcgctcgc gcggtgtgac gtagtgcgtt
    35341 ttcgggtaga tggtaaaacg tggaatagtg gaaacaatct gcccggtcag cgggtcaaat
    35401 aacgacaatc gttccacttc ctcgtcaaac agttccacgc gaagtgcaat gtcatccgat
    35461 tctgccggga agatatctat cacctcgcca cgaacgcgga aagtaccacg ctggaatgct
    35521 tgatcattac gagcgtattg cagctccgcc agtcggcgca gaatcgcgcg ctgatcgata
    35581 atcataccga ccgtgagatg gagcatcatc ttgagatata aatcaggatc gcccagacca
    35641 taaatcgcgg aaacagacgc caccacaacc acatcacgcc gctccagcat cgctttggtg
    35701 gcggacaaac gcatctgctc aatatgttcg ttaaccgagg catctttctc aatgaaagtg
    35761 tcggaactcg gtacataggc ttccggctga tagtagtcgt agtaggaaac gaaatattcc
    35821 accgcgtttt ccgggaagaa ctctttcatt tcgccataca gctgggccgc cagcgttttg
    35881 ttgggcgcaa gtaccatggt tgggcgctga aggtcagcaa tgacattggc aatggtgaag
    35941 gttttcccgg agccagtcac gccaagtaac gtctggtgcg ccaggccatc ttccagcccc
    36001 tcttcgagac gtcgaatcgc ctctggctga tcgccagaag gtttaaaagc ggaattcagt
    36061 ttgaacggtt tactcatgag tcgctacctg aaggagttgg gcgggcaggt atgtaatttt
    36121 actcgtcgta cttaattatg ccaacaaatt atactggata aaaaaacagt tcatcaccat
    36181 aatatttctg ttacagcgta aactccgctg tcaatcatga gcaaaattta ctctgtggcg
    36241 agataaaact ccggccttac cgggttatcc ccaaagcaac ggctttttta acatttgtca
    36301 agatgagtga tgacagtttt atggcaagag atgcctgttc agtgactgcc attgcattta
    36361 tctaaccagt taaaaaataa aagatatttc attgagccgt ctttaacgcc aattcgcgtg
    36421 caagccgcgt attctctcgc ttgcctcgtg ttttctaact ctaatacaca tggttatcca
    36481 caggaatagt ggataactgt ctgcagcccc tatcccccgc cgcctgggca attcccacat
    36541 tcgccgcatg atgcggaagt aaaatttttt tcgtgattat tttagaattt aattggttaa
    36601 attgcagtca atcga
//
LOCUS       DAPGUL010000038        36256 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.038, whole genome shotgun sequence.
ACCESSION   DAPGUL010000038 DAPGUL010000000
VERSION     DAPGUL010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 36256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36256
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.038"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            331..945
                     /gene="evgA"
                     /locus_tag="RHX21_002054"
     CDS             331..945
                     /gene="evgA"
                     /locus_tag="RHX21_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-sensing system DNA-binding response
                     regulator EvgA"
                     /protein_id="HDV1987236.1"
                     /translation="MNAIIIDDHPLAIAAIRNLLIKNDIEILAELTEGGSAVQRVETL
                     KPDIVIIDVDIPGVNGIQVLETLRKRQYSGIIIIVSAKNDHFYGKHCADAGANGFVSK
                     KEGMNNIIAAIEAAKNGYCYFPFSLNRFVGSLTSDQQKLDSLSKQEISVMRYILDGKD
                     NNDIAEKMFISNKTVSTYKSRLMEKLECKSLMDLYTFAQRNKIG"
     gene            950..4543
                     /gene="evgS"
                     /locus_tag="RHX21_002055"
     CDS             950..4543
                     /gene="evgS"
                     /locus_tag="RHX21_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-sensing system histidine kinase EvgS"
                     /protein_id="HDV1987237.1"
                     /translation="MKFLPYIFLLCCGLWSTISFADEDYIEYRGISSNNRVTLDPLRL
                     SNKELRWLASKKNLVIAVHKSQTATLLHTDSQQRVRGINADYLNLLKRALNIKLTLRE
                     YADHQKAMDALEEGEVDIVLSHLVASPPLNDDIAATKPLIITFPALVTTLHDSMRPLT
                     SSKPVNIARVANYPPDEVIHQSFPKATIISFTNLYQALASVSAGQNDYFIGSNIITSS
                     MISRYFTHSLNVVKYYNSPRQYNFFLTRKESVVLNEVLNRFVDALTNEVRYEVSQNWL
                     DTGNLAFLNKPLELTEHEKQWIKQHPDLKVLENPYSPPYSMTDENGSVRGVMGDILNI
                     ITLQTGLNFSPITVSHNIHAGTQLNPGGWDILPGAIYSEDRENNVLFAEAFITTPYVF
                     VMQKAPDSEQTLKKGMKVAIPYYYELHSQLKEMYPEVEWIKVDNASAAFHKVKEGELD
                     ALVATQLNSRYMIDHYYPNELYHFLIPGVPNASLSFAFPRGEPELKDIINKALNAIPP
                     SEVLRLTEKWIKMPNVTIDTWDLYSEQFYIVTTLSVLLVGSSLLWGFYLLRSVRRRKV
                     IQGDLENQISFRKALSDSLPNPTYVVNWQGNVISHNSAFEHYFTADYYKNAMLPLENS
                     ESPFKDVFSNTHEVTAETKENRTIYTQVFEIDNGIEKRCINHWHTLCNLPASEHAVYI
                     CGWQDITETRDLIHALEVERNKAINATVAKSQFLATMSHEIRTPISSIMGFLELLSGS
                     GLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIESGNYQLQPQWVDIPSLVQNTCHS
                     FGAIAASKSIALSCSSTFPEHYLVKIDPQAFKQVLSNLLSNALKFTTEGAVKITTSLV
                     HIDDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQQTGSGLGLMICKELIKNM
                     QGDLSLESHPGIGTTFTITIPVEITQQVATVEAKAEQPITLPEKLSILIADDHPTNRL
                     LLKRQLNLLGYDVDEATDGVQALHKVSMQHYDLLITDVNMPNMDGFELTRKLREQNSS
                     LPIWGLTANAQANEREKGLNCGMNLCLFKPLTLDVLKTHLSQLHQVAHIAPQYRHLDI
                     EALKNNTANDLQLMQEILMTFQHETHKDLPAAFHALEAGDNRTFHQCIHRIHGAANIL
                     NLQKLINISHQLEITPVSDDSKPEILQLLNSVKEHIAELDQEIAVFCQQND"
     gene            complement(4599..5744)
                     /gene="yfdE"
                     /locus_tag="RHX21_002056"
     CDS             complement(4599..5744)
                     /gene="yfdE"
                     /locus_tag="RHX21_002056"
                     /EC_number="2.8.3.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416872.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA:oxalate CoA-transferase"
                     /protein_id="HDV1987238.1"
                     /translation="MTNNESKGPFEGLLVIDMTHVLNGPFGTQLLCNMGARVIKVEPP
                     GHGDDTRTFGPYVDGQSLYYSFINHGKESVVLDLKNDHDKSIFINMLKQADVLAENFR
                     PGTMEKLGFSWERLQEINPRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYP
                     DAPPVRVGTSLADLCGGVYLFSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMA
                     YIATGKSPQRLGNRHPYMAPFDVFDTQDKPITICCGNDKLFSALCQALELTELVNDPR
                     FSSNILRVQNQAILKQYIERTLKTQAAEVWLARIHEVGVPVAPLLSVAEAINLPQTQV
                     RNMLIEAGGIMMPGNPIKISGCADPHVMPGAATLDQHGEQIRQEFSS"
     gene            complement(5818..6762)
                     /gene="yfdV"
                     /locus_tag="RHX21_002057"
     CDS             complement(5818..6762)
                     /gene="yfdV"
                     /locus_tag="RHX21_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter YfdV"
                     /protein_id="HDV1987239.1"
                     /translation="MLTFFIGDLLPIIVIMLLGYFSGRRETFSEDQARAFNKLVLNYA
                     LPAALFVSITRANREMIFADTRLTLVSLVVIVGCFFFSWFGCYKFFKRTHAEAAVCAL
                     IAGSPTIGFLGFAVLDPIYGDSVSTGLVVAIISIIVNAITIPIGLYLLNPSSGADGKK
                     NSNLSALISAAKEPVVWAPVLATILVLVGVKIPAAWDPTFNLIAKANSGVAVFAAGLT
                     LAAHKFEFSAEIAYNTFLKLILMPLALLLVGMACHLNSEHLQMMVLAGALPPAFSGII
                     IASRFNVYTRTGTASLAVSVLGFVVTAPLWIYVSRLVS"
     gene            complement(6832..8526)
                     /gene="oxc"
                     /locus_tag="RHX21_002058"
     CDS             complement(6832..8526)
                     /gene="oxc"
                     /locus_tag="RHX21_002058"
                     /EC_number="4.1.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxalyl-CoA decarboxylase"
                     /protein_id="HDV1987240.1"
                     /translation="MSDQLQMTDGMHIIVEALKQNNIDTIYGVVGIPVTDMARHAQAE
                     GIRYIGFRHEQSAGYAAAASGFLTQKPGICLTVSAPGFLNGLTALANATVNGFPMIMI
                     SGSSDRAIVDLQQGDYEELDQMNAAKPYAKAAFRVNQPQDLGIALARAIRVSVSGRPG
                     GVYLDLPANVLAATMEKDEALTTIVKVENPSPALLPCPKSVTSAISLLAKAERPLIIL
                     GKGAAYSQADEQLREFIESAQIPFLPMSMAKGILEDTHPLSAAAARSFALANADVVML
                     VGARLNWLLAHGKKGWAADTQFIQLDIEPQEIDSNRPIAVPVVGDIASSMQGMLAELK
                     QNTFTTPLVWRDILNIHKQQNAQKMHEKLSTDTQPLNYFNALSAVRDVLRENQDIYLV
                     NEGANTLDNARNIIDMYKPRRRLDCGTWGVMGIGMGYAIGASVTSGSPVVAIEGDSAF
                     GFSGMEIETICRYNLPVTIVIFNNGGIYRGDGVDLSGAGAPSPTDLLHHARYDKLMDA
                     FRGVGYNVTTTDELRHALTTGIQSRKPTIINVVIDPAAGTESGHITKLNPKQVAGN"
     gene            complement(8580..9830)
                     /gene="frc"
                     /locus_tag="RHX21_002059"
     CDS             complement(8580..9830)
                     /gene="frc"
                     /locus_tag="RHX21_002059"
                     /EC_number="2.8.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formyl-CoA transferase"
                     /protein_id="HDV1987241.1"
                     /translation="MSTPLQGIKVLDFTGVQSGPSCTQMLAWFGADVIKIERPGVGDV
                     TRHQLRDIPDIDALYFTMLNSNKRSIELNTKTAEGKEVMEKLIREADILVENFHPGAI
                     DHMGFTWEHIQEINPRLIFGSIKGFDECSPYVNVKAYENVAQAAGGAASTTGFWDGPP
                     LVSAAALGDSNTGMHLLIGLLAALLHREKTGRGQRVTMSMQDAVLNLCRVKLRDQQRL
                     DKLGYLEEYPQYPNGTFGDAVPRGGNAGGGGQPGWILKCKGWETDPNAYIYFTIQEQN
                     WENTCKAIGKPDWITDPAYSTAHARQPHIFDIFAEIEKYTVTIDKHEAVAYLTQFDIP
                     CAPVLSMKEISLDPSLRQSGSVVEVEQPLRGKYLTVGCPMKFSAFTPDIKAAPLLGEH
                     TAAVLQELGYSDDEIAAMKQNHAI"
     gene            complement(10342..10974)
                     /locus_tag="RHX21_002060"
     CDS             complement(10342..10974)
                     /locus_tag="RHX21_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdX family protein"
                     /protein_id="HDV1987242.1"
                     /translation="MKRLIMATMVTAILASSTVWAADNAPVAAQQQTQQVQQTQKTAA
                     AERISEQGLYAMRDVQVARLALFHGDPEKAKELTNEASALLSDDSTEWAKFAKPGKKT
                     NLNDDQYIVINASVGISESYVATPEKEAAIKIANEKMAKGDKKGAMEELRLAGVGVME
                     NQYLMPLKQTRNALADAQKLLDKKQYYEANLALKGAEDGIIVDSEALFVN"
     gene            11270..11545
                     /gene="ypdI"
                     /locus_tag="RHX21_002061"
     CDS             11270..11545
                     /gene="ypdI"
                     /locus_tag="RHX21_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis lipoprotein YpdI"
                     /protein_id="HDV1987243.1"
                     /translation="MKVNLILFSLFLLVSIMACNVFAFSISGGGSERSYKETEKTSAM
                     TTTHSTKLQPSQAILFKMREDAPPLNLTEETTPPFPTKANYLIHPVR"
     gene            complement(11622..11864)
                     /locus_tag="RHX21_002062"
     CDS             complement(11622..11864)
                     /locus_tag="RHX21_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdY family protein"
                     /protein_id="HDV1987244.1"
                     /translation="MIYLWMFLALCIVCVSGYIGQVLNVVSAVSSFFGMVILAALIYY
                     FTMWLTGGNELVTGIFMFLAPACGLMIRFMVGYGRR"
     gene            12217..13137
                     /gene="lpxP"
                     /locus_tag="RHX21_002063"
     CDS             12217..13137
                     /gene="lpxP"
                     /locus_tag="RHX21_002063"
                     /EC_number="2.3.1.242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311285.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid IV(A) palmitoleoyltransferase"
                     /protein_id="HDV1987245.1"
                     /translation="MFPQCKFSREFLHPRYWLTWFGLGVLWLWVQLPYPVLCFLGTRI
                     GAMARPFLKRRESIARKNLELCFPQHSAEEREKMIAENFRSLGMALVETGMAWFWPDS
                     RVRKWFDVEGLDNLKRAQMQNRGVMVVGVHFMSLELGGRVMGLCQPMMATYRPHNNQL
                     MEWVQTRGRMRSNKAMIGRNNLRGIVSALKKGEAVWFAPDQDYGRKGSSFAPFFAVEN
                     VATTNGTYVLSRLSGAAMLTVTMVRKADYSGYRLFITPEMEGYPTGENQAAAYMNKII
                     EKEIMRAPEQYLWIHRRFKTRPVGESSLYI"
     gene            13493..13564
                     /gene="ypdK"
                     /locus_tag="RHX21_002064"
     CDS             13493..13564
                     /gene="ypdK"
                     /locus_tag="RHX21_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_077777854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein YpdK"
                     /protein_id="HDV1987246.1"
                     /translation="MKYFFMGISFMVIVWAGTFALMI"
     gene            complement(13629..14867)
                     /gene="alaC"
                     /locus_tag="RHX21_002065"
     CDS             complement(13629..14867)
                     /gene="alaC"
                     /locus_tag="RHX21_002065"
                     /EC_number="2.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine transaminase"
                     /protein_id="HDV1987247.1"
                     /translation="MADTRPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMG
                     NPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLRRAISRWYQDRYDVEIDPESEAI
                     VTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNE
                     LERAIRESYPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVY
                     DGWKAPSIMQVPGARDVAVEFFTLSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDYG
                     TFTPLQVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWMVEMPKASMYVWAKI
                     PEPYAAMGSLEFAKKLLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRIRQAIRGIKA
                     MFRADGLLPASSKHIHENAE"
     gene            15244..16941
                     /gene="ypdA"
                     /locus_tag="RHX21_002066"
     CDS             15244..16941
                     /gene="ypdA"
                     /locus_tag="RHX21_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     YpdA"
                     /protein_id="HDV1987248.1"
                     /translation="MHEIFNMLLAVFDRAALMLICLFFLIRIRLFRELLHKSAHSPKE
                     LLAVTAIFSLFALFSTWSGVPVEGSLVNVRIIAVMSGGILFGPWVGIITGVIAGIHRY
                     LIDIGGVTAIPCFITSILAGCISGWINLKIPKAQRWRVGILGGMLCETLTMILVIVWA
                     PTTELGIDIVSKIGIPMILGSVCIGFIVLLVQSVEGEKEASAARQAKLALDIANKTLP
                     LFRHVNSESLRKVCEIIRDDIHADAVAITNTDHVLAYVGVGEHNYQNGDDFISPTTRQ
                     AMNYGKIIIKNNDEAHRTPEIHSMLVIPLWEKGVVTGTLKIYYCHAHQITSSLQEMAV
                     GLSQIISTQLEVSRAEQLREMANKAELRALQSKINPHFLFNALNAISSSIRLNPDTAR
                     QLIFNLSRYLRYNIELKDDEQIDIKKELYQIKDYIAIEQARFGDKLTVIYDIDEEVNC
                     CIPSLLIQPLVENAIVHGIQPCKGKGVVTISVAECGNRVRIAVRDTGHGIDLKVIERV
                     EANEMPGNKIGLLNVHHRVKLLYGEGLHIRRLEPGTEIAFYIPNQRTPVASQATLLL"
     gene            16956..17690
                     /gene="ypdB"
                     /locus_tag="RHX21_002067"
     CDS             16956..17690
                     /gene="ypdB"
                     /locus_tag="RHX21_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator YpdB"
                     /protein_id="HDV1987249.1"
                     /translation="MKVIIVEDEFLAQQELSWLIKEHSQMEIVGTFDDGLDVLKFLQH
                     NRVDAIFLDINIPSLDGVLLAQNISQFAHKPFIVFITAWKEHAVEAFELEAFDYILKP
                     YQESRITGMLQKLEAAWQQQQTSSTPAATVTRENDTINLVKDERIIVTPINDIYYAEA
                     HEKMTFVYTRRESYVMPMNITEFCSKLPPSHFFRCHRSFCVNLNKIREIEPWFNNTYI
                     LRLKDLDFEVPVSRSKVKEFRQLMHL"
     gene            17703..18560
                     /locus_tag="RHX21_002068"
     CDS             17703..18560
                     /locus_tag="RHX21_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDV1987250.1"
                     /translation="MKAPGLPADQQFFADLFSGLVLNPQLLGRVCFASQPASLPVGSL
                     CIDFPRLDIVLRGEYGNLLEAKQQRLVEGEMLFIPARAANLPVNNKPVMLLSLVFAPT
                     WLGLSFYDSRTTSLLHPARQIQLPSLQRGEGEAMLTALTHLSRSPLEQNIIQPLVLSL
                     LHLCRNVVNMPPGNSQPRGDFLYHSICNWVQDNYAQPLTRESVAQFFNITPNHLSKLF
                     AQHGTMRFIEYVRWVRMAKARMILQKYHLSIHEVAQRCGFPDSDYFCRVFRRQFGLTP
                     GEYSARFQG"
     gene            complement(18563..21058)
                     /gene="ptsP"
                     /locus_tag="RHX21_002069"
     CDS             complement(18563..21058)
                     /gene="ptsP"
                     /locus_tag="RHX21_002069"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDV1987251.1"
                     /translation="MLTIQFLCPLPNGLHARPAWELKEQCSQWQSEITFINHRQNAKA
                     DAKSSLALIGTGTLFNDSCSLNISGSDEEQARRVLEEYIQVRFIDSDSVQPTQAELTA
                     HPLPRSLSRLNPDLLYGNVLASGVGVGTLTLLQSDSLDSYRAIPASAQDSTRLEHSLA
                     TLAEQLNQQLRERDGESKTILSAHLSLIQDDEFAGNIRRLMTEQHQGLGAAIISNMEQ
                     VCAKLSASASDYLRERVSDIRDISEQLLHITWPELKPRNNLVLEKPTILVAEDLTPSQ
                     FLSLDLKNLAGMILEKTGRTSHTLILARASAIPVLSGLPLDAIARYAGQPAVLDAQCG
                     VLAINPNDAVSGYYQVAQTLADKRQKQQAQAAAQLAYSRDNKRIDIAANIGTALEAPG
                     AFANGAEGVGLFRTEMLYMDRDSAPDEQEQFEAYQQVLLAAGDKPIIFRTMDIGGDKS
                     IPYLNIPQEENPFLGYRAVRIYPEFAGLFRTQLRAILRAASFGNAQLMIPMVHSLDQI
                     LWVKGEIQKAIVELKRDGLRHAETITLGIMVEVPSVCYIIDHFCDEVDFFSIGSNDMT
                     QYLYAVDRNNPRVSPLYNPITPSFLRMLQQIVTTAHQRGKWVGICGELGGESRYLPLL
                     LGLGLDELSMSSPRIPAVKSQLRQLDSEACRELARQACECRSAQEIEALLTAFTPEED
                     VRPLLALENIFVDQAFSNKEQAIQFLCGNLGVNGRTEHPFELEEDVWQREEIVTTGVG
                     FGVAIPHTKSQWIRHSSISIARLAKPVDWQSEMGEVELVIMLTLGANEGMNHVKVFSQ
                     LARKLVNKNFRQSLFAAQDAQSILTLLETELTF"
     gene            complement(21083..22120)
                     /gene="ypdE"
                     /locus_tag="RHX21_002070"
     CDS             complement(21083..22120)
                     /gene="ypdE"
                     /locus_tag="RHX21_002070"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDV1987252.1"
                     /translation="MDLSLLKALSEADAIASSEQEVRQILLEEADRLQKEVRFDGLGS
                     VLIRLNESTGPKVMICAHMDEVGFMVRSISREGAIDVLPVGNVRMAARQLQPVRITTR
                     EECKIPGLLDGDRQGNDVSAMRVDIGARSYDEVMQAGIRPGDRVTFDTTFQVLPHQRV
                     MGKAFDDRLGCYLLVTLLRELHDAELPAEVWLVASSSEEVGLRGGQTATRAVSPDVAI
                     VLDTACWAKNFDYGAANHRQIGNGPMLVLSDKSLIAPPKLTAWIETVAAEIGVPLQAD
                     MFSNGGTDGGAVHLTGTGVPTVVMGPATRHGHCAASIADCRDILQMEQLLSALIQRIT
                     RETVVQLTDFR"
     gene            complement(22120..23205)
                     /gene="ypdF"
                     /locus_tag="RHX21_002071"
     CDS             complement(22120..23205)
                     /gene="ypdF"
                     /locus_tag="RHX21_002071"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDV1987253.1"
                     /translation="MTLLASLRDWLKAQQLDAVLLSSRQNKQPHLGISTGSGYVVISR
                     ESAHILVDSRYYADVEARTQGYQLHLLDATHTLATIARQIIADEQLQTLGFEGQQVSW
                     ETAHRWQSELNAKLVSATPDVLRQIKTPEEVEKIRLASGIADRGAEHIRRFIQAGMSE
                     REIAAELEWFMRQQGAEKTSFDTIVASGWRGALPHGKASDKIVAAGEFVTLDFGALYQ
                     GYCSDMTRTLLVNGEGVSAESHPLFNVYQIVLQAQLAAISAIRPGVRCQQVDEAARRV
                     ITEAGFGDYFGHNTGHAIGIEVHEDPRFSPRDTTTLQPGMLLTVEPGIYLPGQGGVRI
                     EDVVLVTPQGAEVLYAMPKTVLLTGEA"
     gene            complement(23220..24467)
                     /locus_tag="RHX21_002072"
     CDS             complement(23220..24467)
                     /locus_tag="RHX21_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HDV1987254.1"
                     /translation="MAIKKRSATVVPGASGAAAAVKNPQASKSSFWGELPQHVMSGIS
                     RMVPTLIMGGVILAFSQLIAYSWLKIPADIGIMDALNSGKFSGFDLSLLKFAWLSQSF
                     GGVLFGFAIPMFAAFVANSIGGKLAFPAGFIGGLMSTQPTQLLNFDPSTMQWATSSPV
                     PSTFIGALIISIVAGYLVKWMNQKIQLPDFLLAFKTTFLLPILSAIFVMLAMYYVITP
                     FGGWINGGIRTVLTAAGEKGALMYAMGIAAATAIDLGGPINKAAGFVAFSFTTDHVLP
                     VTARSIAIVIPPIGLGLATIIDRRLTGKRLFNAQLYPQGKTAMFLAFMGISEGAIPFA
                     LESPITAIPSYMVGAIVGSTAAVWLGAVQWFPESAIWAWPLVTNLGVYMAGIALGAVI
                     TALMVVFLRLMMFRKGKLLIDSL"
     gene            complement(24489..24815)
                     /locus_tag="RHX21_002073"
     CDS             complement(24489..24815)
                     /locus_tag="RHX21_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-like phosphotransferase enzyme IIB
                     component 1"
                     /protein_id="HDV1987255.1"
                     /translation="MSKKLIALCACPMGLAHTFMAAQALEEAAVEAGYEVKIETQGAD
                     GIQNRLTAQDIAEATIIIHSVAVTPEDNERFESRDVYEITLQDAIKNAAGIIKEIEEM
                     IASEQQ"
     gene            complement(25034..25999)
                     /gene="glk"
                     /locus_tag="RHX21_002074"
     CDS             complement(25034..25999)
                     /gene="glk"
                     /locus_tag="RHX21_002074"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucokinase"
                     /protein_id="HDV1987256.1"
                     /translation="MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAV
                     IRVYLEEHKVEVKDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFT
                     AVSMAIPMLKKEHLIQFGGAEPIEGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGH
                     VDFAPNSEEEAIILEILRAEIGHVSAERVLSGPGLVNLYRAIVKADNRLPENLKPKDI
                     TERALADSCTDCRRALSLFCVIMGRFGGNLALNLGTFGGVFIAGGIVPRFLEFFKASG
                     FRAAFEDKGRFKEYVHDIPVYLIVHDNPGLLGSGAHLRQTLGHIL"
     gene            26203..27459
                     /locus_tag="RHX21_002075"
     CDS             26203..27459
                     /locus_tag="RHX21_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion channel protein"
                     /protein_id="HDV1987257.1"
                     /translation="MLHPRARTMLLLSLPAVAIGIASSLILIVVMKIASVLQNLLWQR
                     LPGTLGIAQDSPLWIIGVLTLTGIAVGLVIRFSQGHAGPDPACEPLIGAPVPPSALPG
                     LIVALILGLAGGVSLGPEHPIMTVNIALAVAIGARLLPRVNRMEWTILASAGTIGALF
                     GTPVAAALIFSQTLNGSSEVPLWDRLFAPLMAAAAGALTTGLFFHPHFSLPIAHYGQM
                     EMTDILSGAIVAAIAIAAGMVAVWCLPRLHAMMHQMKNPVLVLGIGGFILGILGVIGG
                     PVSLFKGLDEMQQMVANQAFSTSDYFLLAVIKLAALVVAAASGFRGGRIFPAVFVGVA
                     LGLMLHEHVPAVPAAITVSCAILGIVLVVTRDGWLSLFMAAVVVPNTTLLPLLCIVML
                     PAWLLLAGKPMMMVNRPKQQPPHDNV"
     gene            27574..27900
                     /locus_tag="RHX21_002076"
     CDS             27574..27900
                     /locus_tag="RHX21_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2502 domain-containing protein"
                     /protein_id="HDV1987258.1"
                     /translation="MFRSLFLAAALMAFTPLAANAGEITLLPSIKLQIGDRDHYGNYW
                     DGGHWRDRDYWHRNYEWRKNRWWRHDNGYHRGWDKRKAYERGYREGWRDRDDHRGKGR
                     GHGHRH"
     gene            complement(28030..29268)
                     /locus_tag="RHX21_002077"
     CDS             complement(28030..29268)
                     /locus_tag="RHX21_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HDV1987259.1"
                     /translation="MTNYRVESSSGRAARKMRLALMGPAFIAAIGYIDPGNFATNIQA
                     GASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAE
                     IIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGL
                     LLFVAAAYIVELIFSQPNLAQLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSS
                     LTQHLHGGSRQQRYSATKWDVAIAMTIAGFVNLAMMATAAAAFHFSGHTGVADLDEAY
                     LTLQPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFIRFHIPLWVRRTVTMLP
                     SFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSDSKLMGDLVNSKRVKQTGWV
                     IVVLVVALNIWLLVGTALGL"
     gene            29604..30806
                     /gene="nupC"
                     /locus_tag="RHX21_002078"
     CDS             29604..30806
                     /gene="nupC"
                     /locus_tag="RHX21_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease NupC"
                     /protein_id="HDV1987260.1"
                     /translation="MDRVLHFVLALAVVAILALLVSSDRKKIRIRYVIQLLVIEVLLA
                     WFFLNSDVGLGFVKGFSEMFEKLLGFANEGTNFVFGSMNDQGLAFFFLKVLCPIVFIS
                     ALIGILQHIRVLPVIIRAIGFLLSKVNGMGKLESFNAVSSLILGQSENFIAYKDILGK
                     ISRNRMYTMAATAMSTVSMSIVGAYMTMLEPKYVVAALVLNMFSTFIVLSLINPYRVD
                     ASEENIQMSNLHEGQSFFEMLGEYILAGFKVAIIVAAMLIGFIALIAALNALFATVTG
                     WFGYSISFQGILGYIFYPIAWVMGVPSSEALQVGSIMATKLVSNEFVAMMDLQKIAST
                     LSPRAEGIISVFLVSFANFSSIGIIAGAVKGLNEEQGNVVSRFGLKLVYGSTLVSVLS
                     ASIAALVL"
     gene            complement(30856..33045)
                     /locus_tag="RHX21_002079"
     CDS             complement(30856..33045)
                     /locus_tag="RHX21_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor domain-containing phosphodiesterase"
                     /protein_id="HDV1987261.1"
                     /translation="MFVEHNLIKNIKIFTLAFTLTVVLIQLSRFISPLAIIHSSYIFL
                     AWMPLCVMLSILFIFGWRGVVPVLCGMFCTNLWNFHLSFLQTAVMLSSQTFVVLCACA
                     ILRWQLGTRWRYGLTSRYVWQRLFWLGLVTPIGIKCSMYLVGSFFDFPLKISTFFGDA
                     DAIFTVVDLLSLFTAVLIYNMLFYYLTRMIVSPHFAQILWRRDIAPSLGKEKRAFTLS
                     WLAALSVLLLLLCTPYENDFIAGYLVPVFFIIFTLGVGKLRYPFLNLTWAVSTLCLLN
                     YNQNFLQGVETEYSLAFILAVLISFSVCLLYMVRIYHRSEWLNRRWHLQALTDPLTLL
                     PNFRALEQAPEQEAGKSFCCLRIDNLEFMSRHYGLMMRVHCIRSIYRTLLPLMQENEK
                     LYQLPGSELLLVLSGPETEGRLQHMVNILNSRQIHWNNTGLDMGYGAAWGRFDGNQET
                     LQPLLGQLSWLAEQSCAHHHVLALDSREEMVSGQTTKQVLLLNTIRTALDQGDLLLYA
                     QPIRNKEGEGYDEILARLKYDGGIMTPDKFLPLIAQFNLSARFDLQVLESLLKWLATH
                     PCDKKGPRFSVNLMPLTLLQKNIAGRIIRLFKRYHISPQAVILEITEEQAFSNAESSM
                     YNIEQLHKFGFRIAIDDFGTGYANYERLKRLQADIIKIDGVFVKDIVTNTLDAMIVRS
                     ITDLAKAKSLSVVAEFVETQQQQALLHKLGVQYLQGYLIGRPQPLVD"
     gene            complement(33253..33328)
                     /locus_tag="RHX21_002080"
     tRNA            complement(33253..33328)
                     /locus_tag="RHX21_002080"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(33293..33295),aa:Ala,seq:ggc)
     gene            complement(33368..33443)
                     /locus_tag="RHX21_002081"
     tRNA            complement(33368..33443)
                     /locus_tag="RHX21_002081"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(33408..33410),aa:Ala,seq:ggc)
     gene            33664..34023
                     /locus_tag="RHX21_002082"
     CDS             33664..34023
                     /locus_tag="RHX21_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311301.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding transcriptional regulator"
                     /protein_id="HDV1987262.1"
                     /translation="MFKERMTPDELARLTGYSRQTINKWVRKEGWTTSPKPGVQGGKA
                     RLVHVNEQVREYIRNAERPEGQGEAPALSGDAPLEVLLVTLAKEMTPVEQKQFTSLLL
                     REGIIGLLQRLGIRDSK"
     gene            34025..34417
                     /locus_tag="RHX21_002083"
     CDS             34025..34417
                     /locus_tag="RHX21_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416898.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding transcriptional regulator"
                     /protein_id="HDV1987263.1"
                     /translation="MKRLRNKMTTEELAECLGVAKQTVNRWIREKGWKTEKFPGVKGG
                     RARLILVDTQVCEFIQNTPAFHNTPMLMEAEERIAEYAPGARAPAYRQIINAIDNMTD
                     IEQEKVAQFLSREGIRNFLARLDIDESA"
     gene            complement(34469..35884)
                     /gene="gltX"
                     /locus_tag="RHX21_002084"
     CDS             complement(34469..35884)
                     /gene="gltX"
                     /locus_tag="RHX21_002084"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HDV1987264.1"
                     /translation="MKIKTRFAPSPTGYLHVGGARTALYSWLFARNHGGEFVLRIEDT
                     DLERSTPEAIEAIMDGMNWLSLEWDEGPYYQTKRFDRYNAVIDQMLEEGTAYKCYCSK
                     ERLEALREEQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQEGSVVFDDQIRGPI
                     EFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALK
                     APVPVYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSHGDQEI
                     FTREEMIKYFTLNAVSKSASAFNTDKLLWLNHHYINALPPEYVATHLQWHIEQENIDT
                     RNGPQLADLVKLLGERCKTLKEMAQSCRYFYEDFAEFDADAAKKHLRPVARQPLEVVR
                     DKLAAITDWTAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGK
                     TRSIERINKALAFIAERENQQ"
     gene            36143..36218
                     /locus_tag="RHX21_002085"
     tRNA            36143..36218
                     /locus_tag="RHX21_002085"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:36176..36178,aa:Val,seq:tac)
BASE COUNT         9509 a         9126 c         8479 g         9142 t
ORIGIN      
        1 gcacattatc ccaggaacgt tggaggccta atttaaatga ggtgcaaaaa aaacaacaga
       61 ggactaaacc gtggcttttg caatacaatt cttacgcctg taggattagt gagaagactt
      121 atagtgctaa tgtgaaacta taaatcatcg gtacaatccc tgattttatt gttgacattt
      181 catatatgcc gactatttat atggtatact tgtcgaatta tcttaaagga agctcaaatt
      241 ttcttatttt tattgagaaa atgagatgat gccttatgtc tgtattacta cagggagaag
      301 ggagatgctt cattgcaaag ggaataatct atgaacgcaa taattattga tgaccatcct
      361 cttgctatcg cagcaattcg taatttattg atcaaaaacg atattgaaat cttagcagag
      421 ttgactgaag gcggaagtgc cgttcagcgg gtggaaacac ttaagcctga tatcgtcatc
      481 attgatgtcg atatccccgg agttaacggt atccaggtgt tagaaacgct gaggaagcgc
      541 caatatagcg gaattattat tatcgtctcc gctaaaaatg accattttta cgggaaacat
      601 tgtgctgatg ctggcgctaa tggtttcgtg agtaaaaaag aaggcatgaa caatatcatt
      661 gcggctattg aagctgcaaa aaatggctac tgctatttcc ccttctctct caaccggttt
      721 gttggaagtt taacgtccga ccagcaaaaa ctcgactcct tatcgaaaca agaaattagt
      781 gtcatgcgct atattcttga tggcaaggat aataatgaca ttgctgaaaa aatgttcatc
      841 agcaacaaaa ctgtcagcac ttataaaagt cgcctgatgg aaaaattaga atgtaaatca
      901 ctgatggatc tttacacatt cgcacaacgt aacaaaatcg gctaaccaca tgaagttttt
      961 accctatatt tttcttctct gttgtggtct ttggtcgacc ataagtttcg cagacgaaga
     1021 ttacatcgaa tatcgtggca tcagtagtaa caaccgtgtc acacttgatc cactacgtct
     1081 gagcaacaag gaattacgtt ggttagcgag caaaaaaaat cttgtgattg cagtacataa
     1141 gtcccaaacg gctacgttgt tgcataccga ttcgcagcaa cgggttcgtg gtattaatgc
     1201 tgattattta aatcttttaa aaagagcgtt aaatatcaaa ttaacactcc gggaatacgc
     1261 cgatcatcaa aaagcaatgg acgcgctgga agaaggtgaa gtcgatatag tgttatcaca
     1321 tttagttgct tcgccgcctc ttaatgatga cattgctgca accaaaccac tgataattac
     1381 ctttccggcg ctggtcacca cccttcacga ttcaatgcga ccgcttacct catcaaaacc
     1441 agtaaatatt gctcgagtag caaattatcc ccctgacgag gtaattcatc aatcatttcc
     1501 aaaagcaaca attatctctt ttacaaattt atatcaggca ttagcatccg tctcagccgg
     1561 acagaatgat tactttattg gtagtaacat cattaccagc agtatgattt cccgctattt
     1621 cactcactcc ttaaatgtag tgaaatatta taactcaccg cgtcaatata attttttctt
     1681 gaccagaaaa gaatctgtcg ttcttaatga agtactcaat cgatttgttg atgctttgac
     1741 aaatgaagtt cgctatgaag tatcacaaaa ttggcttgat acaggaaacc tggcctttct
     1801 gaacaaacca ttagaactca ctgaacatga aaaacaatgg attaagcagc atcccgattt
     1861 aaaggtgctg gaaaatcctt actcgccccc ctattctatg acggatgaaa atggctcggt
     1921 tcggggcgtt atgggggaca ttcttaatat tattaccttg caaacaggtt taaatttttc
     1981 tccgatcacc gtttcacaca atatccatgc tggaacacag ctgaatcccg gcggatggga
     2041 tatattaccc ggtgctattt atagtgaaga tagagaaaat aatgttttat ttgctgaagc
     2101 cttcataaca acgccttacg tttttgtcat gcaaaaagcg cctgacagtg aacaaacatt
     2161 aaaaaaagga atgaaagttg ccattccata ttattatgag cttcattcgc aattaaaaga
     2221 gatgtatccg gaggtagagt ggataaaagt cgataacgcc agcgctgcat ttcacaaggt
     2281 caaggaaggc gaacttgatg ctctggtcgc gacacagtta aattcacgtt acatgatcga
     2341 ccattactat cctaatgaac tttatcattt tcttattccc ggcgttccga atgcatcgct
     2401 ttcgttcgct tttcctcgcg gagaaccgga acttaaggat attattaata aagcactgaa
     2461 tgcaatcccc ccaagcgaag ttctgcgcct gaccgaaaaa tggattaaaa tgcccaatgt
     2521 gaccattgac acatgggacc tctatagcga gcaattttat attgttacga cattatccgt
     2581 tttattagtt ggcagtagcc ttttatgggg attctacctg ttacgctcag ttcgtcgtcg
     2641 taaagtcatt cagggtgatt tagaaaacca aatatcattc cggaaagcac tctcggattc
     2701 cttaccgaat ccaacttatg ttgtaaactg gcaaggtaat gtcattagtc acaatagtgc
     2761 atttgaacat tatttcactg cggattacta caaaaatgca atgttgccat tggaaaacag
     2821 tgaatcaccc tttaaagatg tgttttctaa tacgcatgaa gtcacagcag agacgaaaga
     2881 aaaccgaaca atatacacac aggtatttga aatcgataat ggcatcgaga aaagatgcat
     2941 taatcactgg catacattat gtaatctgcc agccagcgaa catgctgttt atatttgtgg
     3001 ttggcaagat attaccgaga cgcgtgattt aattcatgca ctcgaagtag agagaaataa
     3061 agcgatcaat gcaactgtcg caaaaagtca gtttctggca acaatgagtc acgaaataag
     3121 aacaccaata agctccatta tgggcttcct ggaacttctg tcgggttctg gtcttagcaa
     3181 ggagcaacgg gtggaggcga tttcacttgc ctacgccacc ggacaatcac tcctcggctt
     3241 aattggtgaa atccttgatg tcgacaaaat tgaatcgggt aactatcaac ttcaaccaca
     3301 atgggtcgat attcctagtt tagtccagaa cacttgtcac tctttcggtg cgattgctgc
     3361 aagcaaatcg atcgcattaa gttgcagcag tacgtttcct gaacattacc tggttaagat
     3421 cgaccctcag gcgtttaagc aggtcttatc aaatttactg agtaatgctc tcaaatttac
     3481 caccgagggg gcagtaaaaa ttacgacctc cctggttcac attgatgaca accacgctgt
     3541 aatcaaaatg acgattatgg attctggaag tggattatca caggaagaac aacaacaact
     3601 gtttaaacgt tatagccaaa caagtgcagg tcgtcagcaa acaggttctg gtttaggctt
     3661 aatgatctgc aaagaattaa ttaaaaacat gcagggtgat ttgtcattag aaagtcatcc
     3721 aggcatagga acaacattta cgatcactat cccggtagaa attacccaac aagtggcgac
     3781 tgtcgaggca aaagcagaac aacctatcac actacctgaa aagttgagca tattaatcgc
     3841 ggatgatcat ccgaccaaca ggctattact caaacgccag ctaaatctat taggatatga
     3901 tgttgacgaa gccactgatg gtgtgcaagc gctacacaaa gtcagtatgc aacattatga
     3961 tctgcttatt actgacgtta atatgccgaa tatggatggt tttgagttga ctcgcaaact
     4021 ccgtgagcaa aattcgtcct tacccatctg ggggcttaca gccaacgcac aggctaacga
     4081 acgtgaaaaa gggttaaatt gcggcatgaa cttatgtttg ttcaaaccgt tgaccctgga
     4141 tgtactgaaa acacatttaa gtcagttaca ccaggttgcg catattgcac ctcagtatcg
     4201 ccaccttgat atcgaagccc tgaaaaataa tacggcgaac gatctacaac tgatgcagga
     4261 gattctcatg actttccagc atgaaacgca taaagatcta cccgctgcgt ttcatgcact
     4321 agaagctggc gataatagaa ctttccatca gtgtattcat cgcatccacg gtgcggctaa
     4381 catcctgaat ttgcaaaagt tgattaatat tagccatcag ttagaaataa cacctgtttc
     4441 agatgacagt aagcctgaaa ttcttcagct gctgaactct gtaaaagaac acattgcaga
     4501 gctggaccag gagattgctg ttttctgtca gcaaaatgac taaatagcgg ctcccacaat
     4561 gttcaaatgt gggagctatt taccagcaca tcttacattt atgatgagaa ctcctggcga
     4621 atttgctccc catgctggtc gagcgttgcc gctcccggca taacatgcgg gtccgcgcag
     4681 ccactgattt ttatcggatt acccggcatc attattcccc cggcttcaat caacatattt
     4741 ctcacctgag tttgtggcaa attaatggcc tcagccacac ttaataacgg cgcgacgggt
     4801 acaccaactt catgtattct ggctaaccaa acttcagctg cctgcgtttt taacgtccgc
     4861 tcaatatatt gtttaagaat agcctggttt tgtacgcgta aaatattgct gctaaatctg
     4921 ggatcattaa ccagttccgt aagctccagt gcctggcata acgcagaaaa aagcttgtca
     4981 ttaccacaac aaatcgtaat cggcttatcc tgagtatcga aaacatcaaa aggtgccatg
     5041 tagggatggc gatttcccag gcgttgtggt gacttccctg tcgcaatata tgccatcaga
     5101 ccatgctcca gaaaactcag cgtggcatca aacatcgcta tatcgacatg cgcccctctt
     5161 tggctctttt cgcggccata aagtgcactc actattccgc tgaataaata aacaccgccg
     5221 catagatccg caagagaggt accaacacgc actggcggag catcagggta ccctgtttcc
     5281 atcattatcc cgctcattgc ctgaatgatg gtatcgtagg caggagcatc ttttagcgga
     5341 ccggtatgtc cgaaacctga cgatgaagca tatatgaggc gcgggttgat ttcttgtaac
     5401 ctttcccatg aaaaccccag tttttccatt gtacctgggc gaaaattctc agctaataca
     5461 tcagcttgtt taagcatatt tataaatata cttttatcgt gatcattctt taaatcaaga
     5521 accacactct ctttaccatg attaataaaa ctgtaataga gtgactgtcc atccacatag
     5581 ggaccaaatg tgcgggtatc atcaccatga cctggtggct caactttaat tacccttgcg
     5641 cccatattac aaagaagttg agttccgaaa ggtccattaa ggacatgtgt catatcgata
     5701 actaataagc cttcaaacgg ccctttgctt tcattatttg tcatttgctt atgccttgaa
     5761 aaaagccgaa ggtgaaaaga cacttcggca tttatgtaaa atcaataaca tgattaatta
     5821 tgaaaccagt cgactgacat aaatccacaa gggagccgtg acgacaaaac ccagtacgct
     5881 cacagccaat gacgctgtac cagtgcgggt gtagacatta aaccggctgg caataatgat
     5941 tccggagaat gccggcggta atgcgcctgc cagtaccatc atctgcaaat gttcgctgtt
     6001 caaatgacat gccataccaa cgagaagcag cgccagtggc atcagaatca gcttcaggaa
     6061 ggtgttataa gcaatttcgg cactaaactc gaatttatgt gcagccaggg tcaaccccgc
     6121 agcgaatacc gctacccctg agttagcctt tgcaatcaga ttaaaggttg ggtcccatgc
     6181 tgccggaatt tttaccccaa ccagcaccag gatcgttgcc agaacaggtg cccatactac
     6241 aggctccttt gccgcagaaa ttaatgcgct cagattacta ttcttcttac catccgctcc
     6301 tgaggaagga ttcagcaaat acagaccaat aggaatagta attgcgttaa caataataga
     6361 aataattgct accactaaac ctgttgatac ggaatcacca taaataggat cgagaactgc
     6421 aaaccccagg aatccaatgg taggtgaacc tgcaattaat gcacatacag ctgcttctgc
     6481 atgggtacgt ttaaaaaatt tgtagcaacc aaaccaggag aaaaagaaac atccgacaat
     6541 aaccacaagt gatacaaggg tcagacgagt gtccgcaaaa atcatttccc tgtttgcccg
     6601 ggtaatagat acaaatagag ccgcaggaag agcgtagttt aataccagtt tattaaatgc
     6661 ccgggcttga tcttctgaaa aagtttctcg tctgccgcta aaataaccca acagcatgat
     6721 tacgataata ggcaataaat cgccaataaa aaatgttagc ataatagtat ttccgataag
     6781 ggtcccctca ccatcgcata atgagttggc aagaggagac gatgtcagta tttaattacc
     6841 agcgacttgt tttgggttaa gtttggtaat atggccactt tcagttcctg ctgcagggtc
     6901 gatgaccaca ttaataatgg tcggtttgcg cgactgaata ccggtggtta aagcatgacg
     6961 aagttcatct gtcgtggtga cgttatagcc aacgccacga aacgcatcca ttaatttgtc
     7021 ataccttgca tggtgcaaca gatctgttgg tgatggtgca ccagcgccac tgagatcaac
     7081 accgtctcct ctgtagatgc cgccattatt aaaaataacg atcgtcaccg gcaggttata
     7141 tcgacaaatc gtttcaatct ccatcccact gaaaccaaaa gcactatcac cttcaatggc
     7201 gacaaccgga gaaccagagg tcacgctagc accgatggca tagcccatac cgatgcccat
     7261 gacaccccag gtaccacaat ccagacgacg acgtggttta tacatatcaa taatatttcg
     7321 tgcattatcc agggtatttg caccttcatt aactaaataa atatcctggt tctcacgcaa
     7381 tacatcgcgc acagcactta atgcattaaa gtaatttaat ggttgggtat ctgtacttaa
     7441 tttttcatgc attttttgtg cattttgctg cttgtggata tttaaaatat cgcgccatac
     7501 cagtggagtc gtaaatgtgt tttgtttcag ttctgccagc ataccttgca tactggatgc
     7561 aatatcgcca acgactggca cagcaatggg gcggttgctg tcaatttcct gcggttcaat
     7621 atccagttga ataaactgtg tatctgccgc ccatcctttt ttaccgtgtg ccagtaacca
     7681 attcagtcgt gcaccaacaa gcatgacaac gtcagcattt gccagggcaa acgaacgcgc
     7741 agctgccgca gaaagtggat gcgtatcttc gaggatccct ttcgccatag acattggcag
     7801 gaatggaatc tgggcacttt caataaattc acgaagctgt tcgtcagctt gtgaatacgc
     7861 cgcgcctttg ccaaggataa ttaatggccg ttcagctttt gctaaaagcg aaattgcgct
     7921 agtgactgac ttcgggcatg gcaataatgc tggcgacgga ttttcaactt ttacaatcgt
     7981 ggttaacgct tcgtcttttt ccatcgtcgc ggccaggaca tttgctggca aatcaagata
     8041 aactccgcca gggcgacccg atactgagac ccggatagcg cgtgccaatg caatgccaag
     8101 atcctgcggc tgattaacgc gaaatgctgc tttggcatac ggttttgccg cattcatttg
     8161 gtccagctct tcataatcac cttgctgtag gtcgacgatc gcgcggtcgc tggagccgct
     8221 aatcatgatc atcggaaaac catttaccgt tgcgttggcc aatgcggtca aaccattgag
     8281 gaatcctggc gcagacactg tcaggcagat ccctggtttt tgggtaagaa aaccgcttgc
     8341 cgcagcggca tagcctgccg actgctcatg acgaaaacca atataacgaa tgccttccgc
     8401 ctgggcatgg cgcgccatat ccgtcacagg aatacctaca acaccataaa tagtgtcaat
     8461 attattctgt tttaatgctt caacgatgat atgcatacca tctgtcattt gaagttgatc
     8521 tgacatgatt aataacctcg aaatttttat aaattgggag ccagaagccc ccgttaatat
     8581 cagatggcgt ggttttgctt cattgcagca atttcatcgt cgctataacc cagctcctgc
     8641 aatacagcag cggtatgttc acctaatagc ggcgcagctt taatatctgg cgtaaaggca
     8701 gagaatttca ttggacaacc aactgtcaga tattttccac gcaacggttg ttccacttcg
     8761 acaacactgc cactttggcg caaagaggga tcaagtgaaa tttctttcat acttaaaacc
     8821 ggtgcacaag gaatatcaaa ttgagtcaaa taggccaccg cttcatgttt atcaatagtg
     8881 acagtgtatt tttcgatttc agcaaaaata tcgaaaatat gtggctgtcg ggcatgggct
     8941 gtactgtatg ccggatcggt aatccaatct ggtttgccga tggctttgca ggtgttttcc
     9001 cagttttgct cctgaatagt gaaataaata taggcgttag gatcggtttc ccaaccttta
     9061 catttcagga tccagccagg ctgaccgcca ccacccgcat tacctccgcg gggaactgca
     9121 tcaccaaatg tgccattcgg atactgcggg tattcttcca gataacccaa tttatcgaga
     9181 cgctgctggt cgcgtaattt cacgcggcaa aggttcaata cggcatcctg cattgacatg
     9241 gtgactcgtt gcccacgccc cgttttttcg cgatgcagca aagcagcaag taaaccgatc
     9301 agtaaatgca ttccggtgtt gctgtcaccc aacgctgcag cgcttaccag cggcggaccg
     9361 tcccaaaaac ccgtagtgga tgccgcgcca cccgctgcct gagcaacgtt ttcataggct
     9421 tttacattca cataaggcga acactcatca aaccctttga tcgaaccaaa aatcagacgt
     9481 ggattgattt cttgaatatg ctcccaggtg aaacccatgt gatcaatggc ccctggatga
     9541 aagttctcga ctaagatatc agcttcgcgg atcagctttt ccattacctc tttgccttcc
     9601 gctgttttgg tatttaactc aatagaacgt ttgttactgt taagcatggt gaagtaaagc
     9661 gcatcgatat caggaatatc tcgcagctgg tgacgcgtta cgtcaccaac gccgggacgt
     9721 tcaattttaa taacgtcagc gccaaaccag gccagcattt gagtacaaga tgggccagat
     9781 tgcacaccgg tgaaatcgag aactttaatt ccttgaagtg gagttgacat agcaatacct
     9841 attagttaat taaatatgtg ttaatttagc gtttatttaa ggcataacgc ctctataaat
     9901 aatccgcaaa atatcgtcgt agctgcactc gatattttta cattcctgta tcaagtgctg
     9961 aaaatcattt catcgctact tccaattcct ttctgcatgg taagtagtga ggacgaaaag
    10021 aagaatatga taaatattgg ttcgtggtaa tcagagagag tcgcgacatt tgtgatgtta
    10081 ttcttacaac tgtaagaagc gccggtgatt tacaagtaag ggtatgatta cgctttttaa
    10141 agcgtaccat aaaatataac atattaaatg atttgtgatg acacgggatt attgcggttt
    10201 actttgagga atataaaatg cgagtttata gaacagcgag cgccaaataa ttttatgacc
    10261 acaacctgtc gtattgtggt cataaaaaat tgtcgtctgg agggagttaa atcctttacc
    10321 tcaatatact gccagtcagc attagttcac aaacagtgct tcgctatcga cgatgattcc
    10381 atcttccgca cctttaagcg ccaggtttgc ctcgtagtat tgctttttat caagcagttt
    10441 ctgcgcatca gcaagtgcat tacgagtctg tttaagcggc atcagatatt ggttttccat
    10501 tacaccaaca ccggccaggc gaagctcttc cattgcgccc tttttatccc ctttcgccat
    10561 tttttcattg gcaattttta tcgcggcttc tttttcgggt gtcgctacat aactctcaga
    10621 aattccgaca gatgcattaa tgacaatata ttggtcatca ttgagattgg tctttttacc
    10681 tggcttagcg aactttgccc attcggtact gtcatctgac aacaaagcgg aagcttcatt
    10741 ggtcagttct tttgcctttt ccggatcgcc atgaaacaga gccaggcgcg ctacctgcac
    10801 gtcacgcatc gcatataaac cttgttcaga gatacgctct gctgctgccg ttttctgggt
    10861 ttgctgaact tgctgagttt gctgttgtgc cgctaccggt gcattatcag cagcccatac
    10921 agttgaagat gccagaatag ctgtgaccat cgtagccata attaaacgtt tcatacttac
    10981 ctcattcttt aacagtttta gaaaacgccg ccatcatatt gggtgagcat gaaatgagaa
    11041 atcagagagc aacggtcatt ttgaaagggt tatcttacag ttgtagttat tatcgcaaga
    11101 agtattttag tcttacaatt gtaggaatat gcttcctgtc acagagaact attcttatgt
    11161 accacaaaga gatgtcattt attatatcga tgtaaatatt gattaattaa atgtaaatac
    11221 agccataaca tcgtatgttc tcagtgaacc attttcagga taactttcta tgaaagtaaa
    11281 cttaatactt tttagcttat ttttattggt ctctattatg gcatgcaatg tttttgcatt
    11341 ttccatttct ggtggtggaa gtgagaggag ctataaagag acggaaaaaa catcagcgat
    11401 gacgacaact cactctacaa aacttcagcc atcacaggca attttgttta agatgagaga
    11461 agatgcgcca ccattaaacc tcacagaaga aaccacgccc ccttttccga caaaggcgaa
    11521 ttatcttatt catcctgtgc gatagcgtct gtcacatggc aggtgagcaa tcatgtctga
    11581 tgctgatgtg aacacctgcc caaatgagcc atcctgaccc actatcgcct gccatacccc
    11641 accataaagc gaatcatcaa gccacaagcc ggggcaagaa acataaatat ccccgtcacc
    11701 agttcattac cgcctgttaa ccacatggtg aagtaataaa tgagtgcagc gaggatcacc
    11761 atgccgaaga aagaagagac cgccgatacc acgttcagta cctgaccgat gtatccgctt
    11821 acgcagacaa tacacagggc gagaaacatc cataaataaa tcatagctca acctcctgcc
    11881 gcgctaaaaa acctgtaact tcagtcactt taatagtaag acaatcctta acctctggca
    11941 atttttgcta agcatcaatg aaaacagcat gttaaatgca agactgttgt gtacggaaaa
    12001 atatttactt tgcacgatta ataatcagta gctgaaagca gtcagcgagt gataaagtac
    12061 agataccgca ttcatgctcc tcgtggttat gtcctgacta gtctttacac tctttacagg
    12121 aaccattgtc gtacatgatg gcctaatcaa ttgagtgtac cgctgtcgac atggaatctt
    12181 ctgcgataca acaattcgta tctacagaag gtaactatgt ttccacaatg caaattttcc
    12241 cgcgagtttc tgcatcctcg ctactggctc acatggtttg ggcttggtgt actctggctt
    12301 tgggtacagc ttccttatcc tgttctctgc tttctcggca cgcgtattgg cgcaatggcg
    12361 cgaccattcc tgaaacggcg tgaatctatc gcccgtaaaa acctggaact ttgcttcccg
    12421 cagcattctg cggaagaacg cgagaagatg attgccgaaa actttcgttc actcggcatg
    12481 gcgctggtag aaaccggcat ggcgtggttc tggcccgaca gtcgcgtacg taaatggttt
    12541 gatgttgaag ggctggataa ccttaaacgc gcacaaatgc aaaatcgcgg cgtaatggtt
    12601 gtcggcgtcc attttatgtc gctggaactg ggcggccgcg tgatgggact ttgtcagcca
    12661 atgatggcta cctatcgtcc acataataat cagctgatgg aatgggtgca gacccgtggt
    12721 cgcatgcgct ctaacaaagc gatgatcggc agaaataatc tgcgcggcat tgtcagtgca
    12781 ctgaagaaag gtgaagcggt atggtttgct cccgatcagg attatggtcg taaaggcagc
    12841 tccttcgcgc cgttctttgc ggtagaaaat gtcgccacaa ccaatggcac ctatgttctc
    12901 tcccgtctct ctggcgcagc catgttgacc gtaacgatgg taagaaaagc ggattacagc
    12961 ggatatcgtt tgttcatcac cccagagatg gaaggctacc cgacaggtga aaatcaagcc
    13021 gctgcctata tgaacaagat tatcgagaaa gaaatcatgc gcgcaccgga gcagtacctc
    13081 tggatccacc gtcgctttaa aacgcgcccg gtgggagaat cgtcgttata catttaacaa
    13141 actgctctga ctctttacct cctcacataa gccataataa cctcatggtt tttatggctt
    13201 ttttcttaag gttttttcct tcgctgaata tctaattatt accgtcagaa attaaactgt
    13261 cgccgatatg agacacctgt aagttactaa aagtaaataa gaaaatgcct cttgtctcgt
    13321 ttcagtttta ggcgtacatt agcgccgtct cgagcagttt agctcagaat tctggggtga
    13381 tgcccacggt aaaatacagg acttttaagg tcgttttgcc cggtgtcaac tcactgtatc
    13441 aggtgtaatg aagtcattca ggcgtaacag caattacgcg gagagatgta aagtgaaata
    13501 tttctttatg ggcatttctt ttatggtcat cgtttgggcc ggtacttttg ccctgatgat
    13561 ctaaaagcaa actgtgcaat gaaaaacagg agccatcagg ctcctgtttg catttctgag
    13621 gtcggtgttt attccgcgtt ttcgtgaata tgtttgctgc tggcgggtag taaaccgtcg
    13681 gcacggaaca tcgctttaat cccacgaatc gcctgacgaa tacggtcgcg gttttcaatc
    13741 agtgcaaagc gcacatgcgt atcaccatag tcgccaaagc caatccccgg agagacacag
    13801 accttcgctt cgttaagcaa tttcttggca aattccagcg agcccatggc agcatacggt
    13861 tccggtattt tcgcccagac atacatcgaa gccttcggca tttcgaccat ccagcccgct
    13921 tcatgcagcc ctttaaccaa tacatcacgg cggcgtttgt actgttcggc aatgtcgcgc
    13981 acgcactgtt gatcgccctc cagcgccgca atcgccgcca cctgcaacgg cgtaaaggtg
    14041 ccgtaatcgt gatagctttt aatacgtgcc agcgcactga ccagcgtttt gttgccaacc
    14101 ataaagccga tacgccagcc cgccatgttg tagcttttcg acagcgtaaa gaactcgacc
    14161 gccacatcgc gtgcacctgg cacctgcatg attgacggcg ctttccagcc atcgtagacg
    14221 atatcggcat aggccaggtc atggaccacc agcacatcgt agcgcttcgc cagcgccaca
    14281 accttttcga agaactccag ttccacgcat tgcgcggttg ggttcgacgg gaagccgagg
    14341 atcatcatct tcggtttcgg ataactttca cgaatggcgc gctccagttc gttgaagaaa
    14401 tcgacacctt ccaccagcgg cactgagcgt acctgagccc cggcaatcac cgcgccgtaa
    14461 atatgaatgg ggtaacttgg attcggcacc agcactgtgt caccgtgatc cagtgtcgcc
    14521 agcatcagat gcgccaggcc ctctttcgaa ccaatagtga cgatggcttc tgattccggg
    14581 tcgatttcaa cgtcgtagcg atcctgatac cagcgggaaa tggcgcgacg tagccgcgga
    14641 ataccgcgtg aagtggagta accatgcgtg tccgggcgct gggccacagt acataatttt
    14701 tcgacgatat gcggcggagt cgcaccgtcc gggttaccca tactgaaatc gataatatct
    14761 tcgccgcgcc gacgcgcagc cattttcagt tcagcggtaa tgttaaaaac atagggcggg
    14821 agacgatcaa tgcgcgtaaa gcgacgttca gggcgagtgt cagccataat ttcctcagat
    14881 taacgttagc gcccggaccg tccgagcgac gctgccacga tggtggctgt tttgaaaata
    14941 gcctgattaa tttctgtctg tccagcgttt tagaacattt ttattaatga cgttaaatga
    15001 ggaactctgc tttaaaaaca ggaaaattat ctgcgctaac aagaaaatta ccactcattt
    15061 tattaacata ataatttcaa taaatttact aaccagaagt gcattatcaa gagatgcatt
    15121 gctaatacac catttatcta tcaatcccct tttaaaattg tggtttttcc tcaaaaacgg
    15181 cctgctggtc atcagccttc aggttaccta tcatagaggt ttaatcctta ttcagagtca
    15241 cccgtgcacg aaatattcaa catgctgctg gcggtcttcg atcgggcagc gttaatgctt
    15301 atctgcctgt tctttctcat ccgtatccgt ctgtttcgcg aactgttgca caagtcggcg
    15361 cactccccaa aagagttgct cgccgttacc gccattttct cgctgttcgc cctgttcagc
    15421 acctggtccg gcgttcctgt agaaggttcg ctggtgaacg tacgtattat cgcggtgatg
    15481 tcaggcggga ttctgtttgg cccgtgggtg ggcatcatta ccggcgtgat tgcgggtatt
    15541 caccgttatt taattgatat cggcggcgtg acggcgatcc cctgctttat caccagcatt
    15601 ctggcgggtt gtatatcggg ctggatcaac ctgaaaatcc ccaaagcgca gcgctggcgc
    15661 gtcggtattc tcggcggcat gttgtgtgaa acgttgacca tgattctggt gattgtctgg
    15721 gcaccgacca cagagcttgg gatcgatatc gtctctaaaa tcggcattcc gatgatcctc
    15781 ggcagcgtct gtatcggctt tattgtgctg ctggtgcaaa gcgttgaggg cgaaaaagag
    15841 gccagcgccg cgcggcaggc caagttggcg ctggatatcg ccaacaaaac gctacctctg
    15901 tttcgccatg tcaatagcga gtcattacgc aaagtttgtg aaattattcg cgatgacatt
    15961 cacgccgatg cggtggcgat taccaatacc gatcatgtgc tggcctatgt tggcgtgggt
    16021 gaacataact atcagaatgg cgatgacttc attagcccga ctacccgtca ggcgatgaat
    16081 tacggaaaaa tcatcattaa aaacaatgat gaagcccacc gcacaccaga gattcattcc
    16141 atgctggtga tcccattgtg ggagaaaggc gttgtgaccg gaacgctgaa aatttactac
    16201 tgccacgcgc atcagataac ctcgtcatta caggaaatgg cggttggtct gtcgcaaatc
    16261 atctccacgc aactggaggt ttcacgcgcc gagcagctac gtgaaatggc aaataaggca
    16321 gagcttcgcg ccctgcaaag caaaattaat ccccattttc tgtttaacgc tctgaacgct
    16381 atttcatcgt cgatccgtct gaatccggat accgctcgcc agctgatctt taatctgtcg
    16441 cgttatctgc gctataacat tgaattaaaa gacgatgagc aaatcgatat caaaaaagag
    16501 ctgtatcaaa ttaaagacta tattgccatt gagcaggccc gctttggcga caagctcacg
    16561 gttatctatg atattgatga agaggtgaat tgctgcattc ccagcctgct gatccagccg
    16621 ttggtggaga atgccattgt ccacggtatc cagccttgca aaggtaaagg cgttgtcacc
    16681 atcagcgttg cagagtgcgg caatcgggta cgcattgcgg tgcgggatac cgggcacggc
    16741 atcgatctaa aggtgattga gcgggtcgaa gcgaatgaaa tgccgggcaa taaaattggc
    16801 ctgctgaatg ttcatcatcg cgtgaagtta ttgtatggcg aggggctgca tatccgccgc
    16861 ctggaaccag gaacggaaat tgcgttttac attcctaacc aacgcacccc agtcgcctca
    16921 caggctacgt tattgctttg agccggagtg atattgtgaa agtcatcatt gttgaagacg
    16981 aattcctggc acaacaggaa ctgagctggc taattaaaga gcacagccag atggagattg
    17041 tcggcacctt tgacgacggt ctggacgtgt tgaagttttt gcagcataac cgcgtcgacg
    17101 ccatttttct ggatatcaat attccgtcgc tggatggtgt gttgctggcg caaaacatca
    17161 gccagttcgc ccataaaccg tttattgtgt tcatcaccgc gtggaaagaa catgcggtag
    17221 aagcgtttga actggaggcg tttgactaca ttctcaaacc gtatcaggag tcacgcatta
    17281 ccgggatgct gcaaaaactg gaagcggcct ggcaacaaca gcagaccagc agtacgcctg
    17341 ccgcgacggt aacgcgtgag aatgacacca ttaatctggt gaaagatgag cgaataatcg
    17401 tcacccccat taacgatatc tattacgccg aagcgcacga gaaaatgacc tttgtttata
    17461 cgcggcgtga atcctacgta atgccgatga acattaccga attttgcagc aaactgccgc
    17521 cgtcgcattt tttccgctgc catcgctcat tttgtgtcaa tctgaacaaa atccgcgaga
    17581 tcgaaccgtg gtttaataac acctacattc tgcgactgaa agatctggat tttgaagtgc
    17641 cggtcagccg cagcaaagtt aaagaattcc gccagttaat gcatctttaa tcgggaactt
    17701 tcatgaaagc accaggcttg cccgccgatc aacaattttt cgccgatctg ttcagcggcc
    17761 tggtgcttaa cccgcaacta ctggggcgcg tctgttttgc cagccagcct gcctcgttgc
    17821 cggtgggcag tttatgtatt gattttcccc gtctggatat cgtgctgcgc ggcgaatacg
    17881 gcaatctgct ggaagcaaag cagcaacgtt tggtggaagg agaaatgctg tttattccgg
    17941 cgcgcgcggc taatttaccg gtcaacaaca aaccggtgat gctgttaagc ctggtgttcg
    18001 ctccgacctg gcttgggtta tcgttttacg atagccgcac cacgtcgttg ttgcatcctg
    18061 ctcgccagat ccagcttccc agcctgcaac gcggtgaagg tgaagcgatg cttaccgccc
    18121 tcacccatct tagccgttcg ccgctggagc aaaatatcat tcagccgctg gtgttaagtt
    18181 tgctgcatct ttgccgtaac gtggtgaata tgccgccggg caattcgcag ccgcgcggcg
    18241 attttctcta tcacagcatt tgtaactggg ttcaggataa ttatgcccag ccgctcaccc
    18301 gcgagagcgt ggcgcagttt tttaatatca cgcccaatca tctgtcaaaa ctgtttgctc
    18361 agcatggaac gatgcgtttt atcgagtatg tgcgttgggt gcgaatggcg aaggcgagga
    18421 tgattttgca gaaatatcat ctgtcaattc atgaagtggc acagcgttgc ggttttccgg
    18481 atagcgacta tttttgtcgc gttttccggc gtcagtttgg tctgacgccg ggagagtaca
    18541 gcgcccgttt tcagggctaa cgtcagaagg ttaattctgt ttccagcagc gtcaggatac
    18601 tttgtgcatc ttgcgcggca aacaacgact ggcggaagtt tttattcacc agtttacgcg
    18661 ccagctgcga gaagactttc acatgattca tcccttcgtt agcacccagc gtcagcatga
    18721 tcaccagttc gacttcgccc atttctgact gccagtcaac cggtttcgcc agccgggcaa
    18781 tgctgatact ggaatgacgg atccactgag atttggtgtg cgggatcgcc acgccaaaac
    18841 caacgccagt ggtgacaatc tcttcccgct gccagacatc ctcttccagc tcgaacggat
    18901 gttcagtgcg cccgttaacg ccgaggttac cgcacaggaa ctggatcgcc tgctctttat
    18961 tgctaaaggc ctgatcaacg aagatattct ccagcgccag cagcgggcga acgtcttctt
    19021 ccggcgtaaa ggcggtgagt aacgcttcaa tttcctgcgc gctgcggcat tcacacgcct
    19081 gacgcgccag ttcccgacac gcctcgctat ccagttgacg aagctggctt ttcaccgccg
    19141 gaatgcgcgg gctactcata ctcagctcat ccaggcccag cccaagcagt agcggcagat
    19201 aacggctttc accgcccagt tcaccgcaaa tgcctaccca tttgccccgc tgatgcgcag
    19261 tggtaacaat ctgctgcaac atgcgcagga acgatggcgt aatcgggtta tatagcggcg
    19321 atacgcgcgg gttattacga tcgaccgcat acagatactg ggtcatatcg ttggagccga
    19381 tactgaagaa atcgacctca tcgcagaagt gatcgatgat gtagcacacc gacggcactt
    19441 ccaccatgat acccagcgta atcgtctctg catgacgcag gccatcgcgc ttaagctcaa
    19501 cgatcgcttt ttggatctcg cccttcaccc ataagatctg atcgaggctg tggaccatcg
    19561 ggatcatcaa ctgggcgttg ccgaaactgg cggcgcgcaa aatggcccgc agttgagtgc
    19621 ggaacaggcc agcaaattcc gggtaaatac gtaccgcgcg atagccgagg aacgggttct
    19681 cttcctgggg aatattcaga taaggaatgc ttttatcgcc tccgatgtcc attgtgcgga
    19741 agataatcgg cttgtcgccc gctgccagta gcacctgctg gtaggcttca aattgctcct
    19801 gctcgtccgg cgcgctgtcg cgatccatat agagcatttc ggtacggaac agcccgacgc
    19861 cttccgcgcc gttggcaaac gcgccaggcg cttccagagc ggtgccaata ttcgccgcga
    19921 tatcaatacg cttgttatca cgggaataag ccagctgcgc ggcagcctgc gcctgttgtt
    19981 tttggcgttt atccgccagc gtctgcgcga cctgataata accgctcacc gcgtcattcg
    20041 ggttaatcgc cagcacgccg cactgggcgt caagcactgc aggttgcccg gcataacggg
    20101 caatcgcatc cagcggcagg ccgctcagta ccgggatcgc cgaggcgcgg gccagaatca
    20161 gggtatgcga ggtgcgcccg gttttctcca gaatcatgcc cgcaagattt tttaaatcca
    20221 ggcttaaaaa ctggcttggg gttaaatcct cggccaccag aatagtcggt ttttccagca
    20281 ccagattgtt gcgcggcttc agttccggcc aggtaatatg cagcaactgt tcgctaatat
    20341 cgcgaatgtc gctaacacgt tcgcgcagat aatcgctggc agaagcagaa agtttggcgc
    20401 aaacctgctc catattgctg atgatcgccg cccccagccc ctgatgctgt tctgtcatca
    20461 ggcgacggat attgcctgca aattcatcat cctgaatcag cgacaaatgg gcgctgagga
    20521 tagttttgct ttcgccgtca cgctcacgca attgctggtt cagttgctcg gcaagcgttg
    20581 ccaggctgtg ctccagccgg gtggaatctt gcgcactggc ggggattgcc cgataactgt
    20641 cgaggctgtc gctttgtaac agggtcagcg tacccacgcc gacgccgctt gccagcacat
    20701 tgccgtacag taaatccggg ttaaggcggc ttaatgaacg cggcagcgga tgcgccgtca
    20761 gttctgcctg cgttggctga acgctgtcgc tgtcgataaa gcgcacctgg atgtactctt
    20821 ccagcacgcg ccgcgcctgc tcttcatcgc tgccgctaat gttcaggctg caactgtcat
    20881 taaatagggt gccggtgcca atcagcgcca gcgagctttt ggcatcggcc tttgcgttct
    20941 ggcgatggtt aataaaagtg atttcgcttt gccactggct gcactgttct ttaagttccc
    21001 acgccggacg agcatgtaga ccgttaggca aaggacagag aaattgaatc gttaacataa
    21061 ccgctccggg ttaatcagga gatcatctga aatccgtcag ttgaacaacc gtctcacgcg
    21121 taatacgttg aataagggca gataaaagtt gctccatctg caaaatgtcg cggcaatcgg
    21181 caatcgacgc ggcgcaatgt ccgtggcggg tggcaggccc catcaccact gtgggtacgc
    21241 cggtaccggt taagtgcacc gctccaccgt ccgtgccgcc gttactgaac atatccgcct
    21301 gtaacggcac gccaatttct gccgccacgg tttcaatcca ggcggtgagt tttggcggcg
    21361 caatcagtga cttgtcgctt aacaccagca tcgggccgtt accaatctgg cgatggttag
    21421 ccgcgccata atcaaagttt ttcgcccagc aggcggtatc aagcacaatg gcgacgtccg
    21481 gcgacaccgc gcgggtggca gtttgcccgc cgcgtaatcc cacctcttcg ctggaacttg
    21541 ccaccagcca cacttccgca ggcagttcgg cgtcgtgcag ctcacgtagt aacgtcacca
    21601 gcagatagca accgaggcga tcatcaaagg ctttccccat cacccgctgg tgggggagaa
    21661 cctgaaaagt ggtatcgaac gtgacgcgat cgcctggacg aattcccgcc tgcatcactt
    21721 cgtcatacga gcgcgcgcca atatccacgc gcatggcgct gacatcattc ccctgccggt
    21781 cgccgtcaag caggcctgga attttgcact cttcacgggt ggtgatgcgc accggctgca
    21841 gctggcgggc agccatgcgt acattgccaa ccggcagcac atcaatcgcc ccttcgcggg
    21901 agatgctgcg caccataaat cccacttcgt ccatatgcgc acagatcatc accttcggac
    21961 ctgtcgattc attcaggcgg atcagcaccg atcccagacc atcaaatcgc acttcttttt
    22021 gcaggcgatc cgcttcttcc agcaggatct gccgcacttc ctgttccgag gaggcgatcg
    22081 catctgcctc gctcaacgct tttaatagcg ataaatccat tatgcctctc ccgtgagcaa
    22141 cactgttttc ggcatggcgt agagcacttc tgcgccttgc ggggtgacca gcacaacatc
    22201 ctcgatgcgc acgccccctt gccctggcaa ataaatcccc ggctccacgg tcagtaacat
    22261 gcctggctgt agcgtcgtgg tatcccgcgg tgaaaagcgc ggatcttcgt gtacttcaat
    22321 gccaatagca tgaccggtgt tgtgaccaaa atagtcgcca aatcctgcct cggtaatcac
    22381 ccgacgcgcg gcttcgtcaa cctgctggca gcgcacgccg gggcgaattg cagagattgc
    22441 tgcgagctgt gcctgcaaaa caatctgata gacgttaaac agcggatgag attcggcgct
    22501 caccccttcg ccattcacca gcaaggtgcg cgtcatatca gagcagtagc cctgatacag
    22561 cgcaccgaaa tcgagagtga caaactcgcc cgctgcaaca atcttgtcgc tggctttgcc
    22621 gtgcggcagc gccccacgcc agccactggc gacaatggtg tcaaaagagg ttttttctgc
    22681 gccctgctgg cgcataaacc actccagttc agcggctatc tcgcgctcgc tcatccccgc
    22741 ctgaataaag cggcgaatat gctctgcacc gcgatcggca atcccactgg caaggcggat
    22801 tttctccacc tcctctggcg ttttgatttg ccgcagcaca tccggcgtgg cgctaaccag
    22861 tttcgcattg agttcagact gccagcggtg cgcggtttcc caactcacct gctggccttc
    22921 aaaaccgagc gtttgcaact gctcatcggc aatgatttgc ctggcgatgg ttgcaagcgt
    22981 gtgcgtcgcg tcaagcaaat gcagctggta gccttgcgtg cgggcttcca catccgcgta
    23041 atatcgcgaa tccaccagaa tgtgcgcact ttctcggcta atcaccacat aaccagatcc
    23101 ggtggagatc cccagatgcg gctgtttgtt ctgccgtgat gagagaagca ctgcatccag
    23161 ttgttgcgcc ttaagccagt cgcgcagcga agcgagtaat gtcatctgga ttttccttct
    23221 tacaggctat cgattaacaa tttgccttta cggaacatca tcagacgcag gaacaccacc
    23281 atcagcgcag ttatgactgc ccccagcgcg atccccgcca tgtagacgcc gaggttagtg
    23341 accagtggcc atgcccagat agcggattcc gggaaccatt gcactgcgcc cagccagaca
    23401 gcggcggttg agccgacaat cgcgccaacc atatacgacg gaatggcggt gatggggctt
    23461 tccagtgcaa acggaattgc accctcacta atccccataa aggcaaggaa catcgcggtc
    23521 ttaccctgcg gataaagttg tgcgttgaac aggcgtttgc cggttaaacg acggtcaata
    23581 atggtcgcca gacccagacc aatcggcgga ataacgatag cgatagaacg tgcggtgacc
    23641 ggtaatacgt ggtcagtggt aaagctgaag gcaacaaaac ctgcggcttt gttgatcggg
    23701 ccaccaaggt cgattgctgt cgccgcggcg atccccattg cgtacatcag cgcgcccttc
    23761 tcacctgcgg cagtcagcac ggtacggata ccgccgttga tccagccacc aaatggtgtg
    23821 atgacgtagt acatcgccag catgacaaaa atagcggaaa gaatcggtag caaaaatgtg
    23881 gttttgaacg ctaacaggaa atccggtaac tggattttct ggttcatcca tttcacaagg
    23941 taaccggcaa cgatagaaat aatcagcgca ccaataaagg tggacggcac cggcgaagag
    24001 gtcgcccatt gcatagtgct gggatcgaag ttcagcagtt gcgtcggctg ggtagacatc
    24061 aagccgccga taaaaccagc cggaaacgcc agtttgccac cgatagagtt cgccacaaaa
    24121 gcagcaaaca tcggaatggc aaaaccaaac aacacgccgc cgaaggactg cgacaaccag
    24181 gcaaatttca gtaaggagag gtcgaaaccg gagaatttcc cgctattaag agcatccatg
    24241 atgccgatat cagcaggaat tttaagccag ctataagcaa tcaactggct gaaagcgagg
    24301 atcacaccgc ccataattaa ggttggcacc atgcgtgaaa tccctgacat cacatgctgc
    24361 gggagttcac cccagaagct gcttttagag gcctgcggat tcttaactgc cgctgccgca
    24421 ccggatgcgc caggcacaac ggttgcactg cgttttttaa tggccataac aattatccct
    24481 gtcgaatatt actgttgttc agaggcaatc atctcttcga tttctttgat gatgcccgca
    24541 gcgtttttaa ttgcgtcctg caaagtgatt tcataaacgt cgcgtgattc gaaacgttcg
    24601 ttatcttccg gggtaactgc cacggaatgg atgatgatgg tcgcttcggc gatatcctgc
    24661 gccgtcaggc gattctggat gccgtccgcg ccctgggttt caattttcac ttcataaccg
    24721 gcttctaccg ccgcttcttc cagcgcctga gcggccataa aggtgtgagc caggcccatc
    24781 gggcaggcac ataaggcaat cagtttctta ctcatcgtta attcctcgtt cagtgatagt
    24841 tgacgagtga aattatgaac gtgcaaaaca aatcgccgtt accagacaaa taatgcattt
    24901 actggagaat taatcccgct gtacggaagt gtgacgcagg tcggccttgt gaggggacac
    24961 aaagaaaaat tgaattaact gtatgattta aaagattatc gggagagtta cctcccgata
    25021 taacaggaag gatttacaga atgtgaccta aggtctggcg taaatgtgca ccggaaccga
    25081 gaagacccgg attgtcatgg acgatgagat acaccggaat atcatggaca tattctttaa
    25141 agcgcccttt atcttcaaat gcggcacgga aaccagaggc tttgaagaac tcaaggaagc
    25201 gcggcacgat accgcccgca ataaacacgc cgccaaatgt cccgagattg agcgccagat
    25261 tgccgccaaa acggcccata atgacgcaaa acagcgacaa cgcacggcgg caatcggtgc
    25321 agctgtcagc cagcgcgcgt tcagtaatat cttttggctt gagattttct ggcaggcggt
    25381 tgtcagcttt cacaattgcg cgatacaaat tcaccagccc tgggccagaa agcacgcgtt
    25441 ccgccgaaac atgaccaatt tccgcacgca atatttcgag gataatggcc tcttcttcac
    25501 tattcggcgc aaaatcaacg tgaccgcctt cgcccggcaa gcttacccaa cgcttatcga
    25561 catggaccag atgcgcaacc ccaagccccg ttccggcacc gtaaaccgca ataggcttac
    25621 cttctatcgg ctctgcgcca ccaaactgaa tcagatgctc ttttttcagc atcgggatcg
    25681 ccatcgatac agcggtaaaa tcgttaataa tttccagatg gctaaaaccg agattctttt
    25741 tcatttcggc aattgagaac gcccaggtat ggttggtcat tgccacccag tcaccggtaa
    25801 ttgggcaagc gatggcaata cagccgtctt tcacctcgac cttatgttct tcaagataaa
    25861 cgcgaatgac cgcttcgagg ctggggtaat caagccctga ataggtctta gcctgcgaga
    25921 tttcaccact ggcaatatca cacagagcaa gacgtgcgtt ggtgccgccc acatcaccga
    25981 ctaatgcata ctttgtcatt cttcaactgc tccgctaaag tcaaaataat tctttctcac
    26041 actgtaaata cctgggggca taacaacaac gccggaaagg caggctccct gtaaatatcg
    26101 atctgggtca cacaattact ttatcgtttc agcaccaatt gcagcgatgc ctttttgcaa
    26161 gctgggcaaa ctaagtatct gaccccgcat aaggaataga acatgctcca tccgcgagcc
    26221 agaaccatgt tgttattatc gctccccgcc gtggcaattg ggattgcgtc cagtcttatt
    26281 ctgattgtgg tgatgaaaat cgcctcggta ttacagaatt tgctctggca acgactgccg
    26341 ggaactctgg ggatagccca ggattcaccc ctctggatca tcggtgtatt aacgctaacg
    26401 ggtattgcgg tggggttggt tatccgtttc agccagggtc atgccggacc agaccccgcc
    26461 tgtgaaccgc tgatcggcgc accggttccg ccctctgcgc taccaggact tatcgtagca
    26521 ttaattctcg gtcttgctgg cggcgtcagc ctggggccgg aacatccgat catgaccgtc
    26581 aatatcgccc ttgcggttgc cattggcgct cgtctgttac cgcgcgtcaa ccgaatggag
    26641 tggactattt tagcctctgc cggaaccatc ggcgcgctgt ttggtacacc tgttgcggcg
    26701 gcgttgatat tttcgcaaac cttaaatggc agtagtgaag ttccgctatg ggatcgtctt
    26761 tttgcgccgt taatggcggc agcagctggt gcacttacta ccggattatt tttccatccc
    26821 catttttcac tgcccattgc gcattacgga cagatggaaa tgaccgatat tctcagcggt
    26881 gcaattgtcg cggcgattgc catcgcagca gggatggtcg ccgtatggtg cttaccacgg
    26941 ttgcacgcga tgatgcatca aatgaaaaat ccggtgctcg tgctgggtat tggcggattt
    27001 attctcggta ttctgggggt tattggtgga ccagtttcgc tgtttaaagg gctggatgag
    27061 atgcagcaga tggtggcaaa tcaggctttc agcaccagcg attacttttt gctggcggta
    27121 attaaacttg ccgccctggt cgttgctgcc gccagtggct ttcgcggtgg gcgaatcttc
    27181 ccggcagtgt ttgtcggcgt ggcattaggg ttgatgctgc atgagcacgt tcccgccgta
    27241 ccagcggcaa taaccgtttc ctgcgctatt ctcggcatcg tgctggtggt aacacgcgat
    27301 ggctggttaa gtctttttat ggcggcagtc gttgtaccca ataccacatt gctaccgctg
    27361 ctctgtatcg tcatgcttcc ggcatggctg ttattagcag gtaagccgat gatgatggtc
    27421 aatcgtccga agcaacagcc accccacgat aacgtttagc aaaaaatgct ctcctttatg
    27481 atttaagagt tatggcgatg atacggggct ttacctcccc gtaatattgc gttaacaggc
    27541 cgctgacggc ttcgatcgtg aaggagaata acaatgttca ggtcactgtt tctggcggcc
    27601 gccctgatgg catttacccc gcttgcagca aacgcaggtg aaatcaccct actgccatca
    27661 atcaaattac aaattggcga tcgcgatcat tacggtaatt actgggacgg tggtcactgg
    27721 cgagatcgtg attactggca tcgcaattat gagtggcgca aaaaccgctg gtggcgtcat
    27781 gataatggct atcatcgtgg ctgggataag cgtaaagcgt atgagcgtgg ctatcgtgaa
    27841 ggctggcgcg atcgtgacga tcatcgcgga aaaggccgcg gacatggaca ccgccattaa
    27901 acacattcgc caatggagca caaggcctga tgcgtcttat caggcctaca aaccggctct
    27961 ttaacgcgta gggcggataa ggcgtttacg ccgcatccgc caatggtgcc aaatgcgaca
    28021 ccagttgaac tacaatccca gcgccgttcc taccagcaac cagatattca gcgccacgac
    28081 cagcaccaca atcacccagc ctgtctgttt tacgcgtttg ctgttcacca gatcgcccat
    28141 caacttgctg tcactggtga aaatcagcag tggaaccagc gccagggcga taccaaaact
    28201 taacagcacc tgactcataa ccagaatccg tgtcggatct aatcccatca gaatgacaat
    28261 aaatgacggc agcatggtga ctgtacgacg cacccacagc gggatatgga agcgaatgaa
    28321 cccctgcatc accacctgcc ctgccagtgt ccccaccacc gttgaggaca gtccggcagc
    28381 aaccaggctt aacccaaaga ccgttgccgc agcatggctt aacaacggtt gcagcgtcag
    28441 ataagcctca tcaagatcgg caacaccagt atgaccagaa aagtggaacg ccgccgcagc
    28501 tgtagccatc atcgccagat tgacaaaacc ggcaatagtc atggcgatag ccacatccca
    28561 tttggtggcg gaataacgtt gttgacgcga accgccatgt aaatgttgag tgagcgaaga
    28621 gtgcaaataa atcacatgcg gcataatcgt cgcccctaac acgcctgctg ccaggaagac
    28681 cgcctccgaa gtaggtaaac ttgggatcac cattccttta cccagctgcg ccaggttagg
    28741 ctgggagaaa atcaactcga caatgtaagc cgcggcaaca aacaatagca acccgccaat
    28801 cactttctcc aacggttttt gcccgcgacg ttgcagcatt aaaatcagga aagtcgcgat
    28861 ccccgtcagc accgcgccct gcaacaacga aacaccaaga atgagtttaa aaccgatcgc
    28921 cgcaccaata aattccgcca ggtcggttgc catcgcaata atttctgcct gaacccaata
    28981 gaaccacact acgggacgcg gatagtgatc gcgaatctgc tccgccagat ttttaccggt
    29041 ggcaatccct agtttggcag agaggatctg aatcagcatc gccatcaggt tggcccaaac
    29101 gacaacccac agtagctgat agccgaagct ggcacccgcc tgaatattgg tcgcaaagtt
    29161 accgggatcg atataaccaa tcgccgcaat gaacgcaggt cccattaatg cgagcctcat
    29221 cttgcgcgcc gcccgtccgc tgctactctc aacgcgatag ttcgtcatct tgtgcctcta
    29281 aaacatagcc tttgctatgt ttcatgctat gccaaacgag aatgattatc aaattcattt
    29341 aaatgggttg tggtgatttc tctgatagac caggattatg actacgaaaa gattgatgac
    29401 ttgaatgtta tggttatgtt taatgttagc acatttacat aactttcagc ttccatacac
    29461 aacatagcag aaatgtatga cagctcacta tttttgaagc ttgtcacagg acgtcattat
    29521 agtgtgtgtc agatctcgtt ttccttaacc atgttacata gaatgtgcac ggaaatttaa
    29581 cctgcctcat atttggagca aatatggacc gcgtccttca ttttgtactg gcacttgccg
    29641 ttgttgcgat tctcgcactg ctggtaagca gcgaccgcaa aaaaattcgt atccgttatg
    29701 ttattcaact gcttgttatc gaagtgttac tggcgtggtt cttcctgaac tccgacgttg
    29761 gtttaggctt cgtgaaaggc ttctccgaaa tgttcgaaaa actgctcgga tttgccaacg
    29821 aagggactaa cttcgtcttt ggtagcatga atgatcaagg cctggcattc ttcttcctga
    29881 aagtgctgtg cccaatcgtc tttatctctg cactgatcgg tattctccag cacattcgcg
    29941 tgttgccggt gattatccgc gcaattggtt tcctgctctc caaagtcaac ggcatgggca
    30001 aactggaatc ctttaacgcc gtcagctccc tgattctggg tcagtctgaa aactttattg
    30061 cctataaaga tatcctcggc aaaatctccc gcaatcgtat gtacaccatg gcagcaacgg
    30121 cgatgtccac cgtatctatg tccatcgttg gtgcatacat gaccatgctg gagccgaaat
    30181 atgtcgttgc ggcgctggta ctgaacatgt tcagcacctt tatcgtgctg tcgctgatca
    30241 acccttaccg tgttgatgcc agtgaagaaa acattcagat gtccaacctg cacgaaggtc
    30301 agagcttctt cgaaatgctg ggtgaataca ttctggcagg tttcaaagtt gccattatcg
    30361 ttgccgcaat gctgattggc tttatcgccc tgatcgccgc gctgaacgca ctgtttgcca
    30421 ccgtgactgg ctggtttggc tacagcatct ccttccaggg catcctgggc tacatcttct
    30481 atccgattgc atgggtgatg ggtgttccgt ccagcgaagc actgcaagtg ggtagtatca
    30541 tggcgaccaa actggtttct aacgagttcg ttgcgatgat ggatctgcag aaaattgctt
    30601 ccacgctctc tccgcgtgct gaaggcatca tctctgtgtt cctggtttcc ttcgctaact
    30661 tctcttcaat cggaattatt gcaggtgcag ttaaaggcct gaatgaagag caaggtaatg
    30721 tggtttctcg cttcggtctg aaactggttt acggctctac cctggtgagt gtgctgtctg
    30781 cgtcaatcgc agcactggtg ctgtaagacc atacataaaa aagccgggga taattccccg
    30841 gcttttttac gcctgttaat caactaatgg ctgcgggcgt ccaatcaaat acccttgcag
    30901 atattgcacc ccgagcttat gcaatagcgc ctgctgctgt tgcgtctcga caaactccgc
    30961 gaccacactc aatgacttcg ctttcgccag atcggtaatt gatctcacaa tcatcgcatc
    31021 cagcgtattc gtgacaatat ctttcacaaa gacgccatca attttgatga tatcagcctg
    31081 caaacgcttt aaccgttcgt agttggcata tccggtgcca aagtcatcaa tcgcaatccg
    31141 gaaaccaaac ttatgcagct gctcgatgtt gtacatgctg ctttctgcgt tagaaaacgc
    31201 ctgctcctcg gtgatctcaa gaatgaccgc ctgcggggag atgtgataac gcttaaacag
    31261 acgaataatc cgcccggcaa tattcttttg cagcagcgtg agcggcatta aattgactga
    31321 aaagcgcggg ccttttttgt cgcaagggtg tgttgccagc cacttcaaca aggattccag
    31381 cacttgcaaa tcaaaacgcg cgctaagatt aaactgagca ataaggggca gaaacttatc
    31441 cggggtcata atgccgccgt catatttcag tcgcgcgagg atctcatcat aaccttcacc
    31501 ctctttgttg cgaattggct gggcgtagag cagcaaatca ccctgatcta acgccgtgcg
    31561 aatggtattc agcaatagca cctgtttagt ggtctgcccg gaaaccatct cctctcggct
    31621 atccagcgcc agcacatgat gatgtgcgca ggattgctcc gccagccagc ttaactgccc
    31681 caacaagggt tgcagggttt cctgatttcc atcaaaacgc ccccaggcag caccatagcc
    31741 catatccagc ccggtattgt tccagtgaat ttgccgacta ttcaggatgt taaccatatg
    31801 ctggagtcgc ccttccgttt ccggcccgct cagcactaac agcagttcac tacccggcaa
    31861 ttgatacaac ttttcgtttt cctgcatcaa cggcagcagc gtacggtaaa ttgatcggat
    31921 acagtgaacg cgcatcatta acccgtaatg acgactcata aactcaagat tatcaatgcg
    31981 caggcagcaa aaactcttgc ccgcctcttg ctccggcgct tgttccaacg cacgaaagtt
    32041 gggcaggagc gttaacggat cggtcagcgc ctgcaaatgc cagcggcgat taagccattc
    32101 actgcgatga taaatgcgca ccatatagag caggcaaacg ctaaaggaaa tcagcaccgc
    32161 aagaataaat gccagcgaat attcggtttc caccccttgc aaaaagttct ggttgtaatt
    32221 cagcaggcaa agcgttgaaa cagcccaggt gagatttaaa aacggatagc gaagcttacc
    32281 gaccccgagg gtaaagatga tgaagaaaac gggtaccagg taaccggcaa taaagtcgtt
    32341 ttcataaggt gtgcacaaca gaagtagcag cacgcttaac gctgccagcc agcttaaggt
    32401 aaatgcgcgt ttctctttgc ccaacgacgg agcgatatcc ctgcgccaca atatctgcgc
    32461 aaagtgggga cttacaatca tgcgagtgag atagtagaaa agcatgttgt aaatcagcac
    32521 cgcggtgaaa aggcttagca aatcaacgac cgtgaaaatg gcatccgcat cgccgaaaaa
    32581 ggtggatatc tttagcggga aatcaaagaa gctccccaca agatacatgc tgcatttgat
    32641 gccgatcggc gtcaccaaac caagccagaa cagacgttgc cagacatatc ggctggtcaa
    32701 tccataacgc caacgcgtcc ccagctgcca gcgtaatatt gcgcaggcac ataacacgac
    32761 aaacgtctgg ctgctgagca tgaccgcagt ctgtaaaaaa gagagatgaa agttccacag
    32821 attggtgcaa aacatcccgc ataaaacggg aacgacaccg cgccagccaa agataaacaa
    32881 gattgacagc attacgcaca gtggcatcca cgccagaaag atataactgg aatggataat
    32941 ggcaagtggc gaaataaaac gggaaagctg aataagtacc acggtgagcg taaacgctag
    33001 tgtgaatatc ttgatatttt ttatcaggtt atgctccaca aacatgagta cactactctc
    33061 actgatcggg gttttcaggc acacaaataa taagtttatt cgcatcgcga agcaaacaag
    33121 ggccagcctg ttgccgattt ttcatccaat gatgctttca ccaggcggcg ctaacccgga
    33181 cgtagactgt attacaaaag cggcaaaaag cagagacaaa aaacccccgc tttgcagcga
    33241 gggttggaaa tttggtggag ctaagcggga tcgaaccgct gacctcttgc atgccatgca
    33301 agcgctctcc cagctgagct atagccccac gatgcgttta cgtaccaaat ttgctgggtg
    33361 caaaatttgg tggagctaag cgggatcgaa ccgctgacct cttgcatgcc atgcaagcgc
    33421 tctcccagct gagctatagc cccgtcacgt aaagcttgtc gagttgacgg gcggcatcat
    33481 atgaattccg cccgaatgtg tcaacggcaa attgcaacgt gtagtttcaa tcgctgaaaa
    33541 atcaggcaaa tgaacaattt tggaaaaccg ctcgcattca gtagttattc atgtcacggt
    33601 ttcctgtaaa gtggtgctat aaaatgaact actaatagac ccacatacat tcagggaatt
    33661 gttatgttca aggagaggat gacgccagat gaacttgcca gactgaccgg ctatagccgc
    33721 cagaccatta ataaatgggt acgcaaggaa ggctggacga cgtcaccaaa accaggcgtc
    33781 cagggtggca aagcccgact ggttcacgtc aatgaacagg ttcgtgaata tattcgtaat
    33841 gctgaacgtc cagaaggtca gggagaagcg cctgcccttt ctggtgatgc gccgcttgaa
    33901 gtattgctgg tgacactggc gaaagagatg acgccagttg aacaaaaaca gtttacatcc
    33961 ttgcttctgc gggaagggat tatcggattg ttacaacgct tagggattcg cgatagcaaa
    34021 taatatgaaa agattacgca ataaaatgac caccgaagaa ctggctgaat gcctcggtgt
    34081 ggctaaacaa actgttaacc gttggatcag agaaaaaggc tggaaaacgg aaaaatttcc
    34141 cggcgtgaaa ggcggtcgtg ccagacttat tctggtcgat acgcaagttt gcgagtttat
    34201 tcagaacacg cctgcgttcc ataacacacc aatgttgatg gaagctgaag agagaattgc
    34261 tgaatacgct cctggagcac gcgccccggc gtatcgacaa atcatcaacg cgatagataa
    34321 tatgacagac attgagcagg aaaaagtcgc gcaatttttg tcacgtgaag gaattcgcaa
    34381 tttcctcgcc cgtctcgata ttgacgaatc agcataaata aaaaacggca ggatattatc
    34441 tcctgccgtt tatcttttta cacgctaatt actgctggtt ttcgcgttca gcaataaagg
    34501 ccagcgcttt gttgatacgc tcaatgctac gtgtcttacc gattgcgtga acggtaacat
    34561 ccagtgccgg agactgcccc gcaccggtta cggcgacacg cagcggcata ccaactttac
    34621 ccatacccac ttccagctca tccgccgtcg cctgaatagc gtgatgaacg ttttcagcgg
    34681 tccagtcagt aatcgcggcc agtttgtcac gaaccacttc cagcggctga cgcgctaccg
    34741 gacgcagatg ttttttcgcg gcgtcggcat cgaactcagc aaaatcttcg tagaaataac
    34801 ggcagctctg tgccatctct ttcagcgtct tgcagcgttc gcccagcagt ttcaccagat
    34861 cagccagctg cgggccgtta cgggtatcga tattttcctg ctcaatgtgc cactgtaagt
    34921 gagtagcaac atactccggc ggcagcgcgt taatgtagtg atggttcagc cacagcagct
    34981 tgtcggtgtt gaacgcactg gcagatttgc tgacggcatt caaagtgaag tatttgatca
    35041 tctcttcacg agtgaagatt tcctgatcgc cgtgggacca gcccagacgc accagatagt
    35101 tcagcagtgc ttctggcaaa taaccgtcat cacgatactg cattacgctg actgccccgt
    35161 gacgtttgga cagttttttg ccgtcatcgc cgttgatcat agaaacgtgc gcgtaaaccg
    35221 gtaccggcgc tttcagggct ttaagaatgt tgatctggcg tggcgtgttg ttgatatggt
    35281 cttcgccacg gataacgtgg gtgatttcca tatcccagtc atcgacaacc acacagaagt
    35341 tataggttgg ggaaccatcg gtacggcgga taataagatc gtccagttcc tggttgctga
    35401 actcgatcgg accacggatc tgatcgtcaa aaacaacaga accttcctgc gggttagcaa
    35461 aacgtacgac acacggctca tcatcagcgt gatgctcatg actgtggcgg cagcgaccgt
    35521 cataacgcgg cttctcacct ttcgccattt gttcttcgcg cagcgcttcc aggcgctctt
    35581 tagagcaata gcatttataa gcagtgccct cctccagcat ctgatcgatc actgcgttgt
    35641 agcgatcaaa acgtttggtc tggtagtacg gaccttcatc ccactccagg ctcagccagt
    35701 tcatgccatc cataatggct tcgatagctt ccggcgtgga acgctcaaga tcggtgtctt
    35761 caatacgcag cacgaactca ccgccgtggt tacgtgcaaa aagccaggag taaagagcag
    35821 tacgcgcgcc gccaacgtgc agatagcctg ttgggcttgg cgcgaagcga gttttgattt
    35881 tcatgaaatg gccttacgtt tagaaagatg ccgacaaccg gcaaatcctg gaaaaattga
    35941 gtgggcgata ttctatcact cccgcctgat tcctcaatgt agttcgggtt tctaccttac
    36001 gcattattgt tttcgttgac aaattgcgca acacggtctg ttttgcgatc atcttgctta
    36061 aatttacgac gaacgaacaa tttctttaga aaatgcgttg actcattttg aactctccct
    36121 ataatgcgac tccacacagc gggggtgatt agctcagctg ggagagcacc tcccttacaa
    36181 ggagggggtc ggcggttcga tcccgtcatc acccaccaac tactttatgt agtctccgcc
    36241 gtgtagcaag aaattg
//
LOCUS       DAPGUL010000039        35704 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.039, whole genome shotgun sequence.
ACCESSION   DAPGUL010000039 DAPGUL010000000
VERSION     DAPGUL010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 35704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35704
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.039"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..327
                     /locus_tag="RHX21_002086"
     CDS             <1..327
                     /locus_tag="RHX21_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2170 family protein"
                     /protein_id="HDV1987265.1"
                     /translation="ESALIIKMNDYGDLQINILFTSRQMIIETFICPVSSISNPDEFN
                     TFLLRNQKMMPLSSVGISSVQQEEYYIVFGALSLKSSLEDILLEITSLVDNALDLAEI
                     TEEYSH"
     gene            346..1044
                     /locus_tag="RHX21_002087"
     CDS             346..1044
                     /locus_tag="RHX21_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspA/IM30 family protein"
                     /protein_id="HDV1987266.1"
                     /translation="MGILKSLFTLGKSFISQAEESIEETQGVRMLEQHIRDAKAELDK
                     AGKSRVDLLARVKLSHDKLKDLRERKASLEARALEALSKNVNPSLINEVAEEIARLEN
                     LITAEEQVLSNLEVSRDGVEKAVTATAQRIAQFEQQMEVVKATEAMQRAQQAVTTSTV
                     GASSSVSTAAESLKRLQTRQAERQARLDAAAQLEKVADGRDLDEKLAEAGIGGSNKSS
                     AQDVLARLQRQQGE"
     gene            1095..1754
                     /locus_tag="RHX21_002088"
     CDS             1095..1754
                     /locus_tag="RHX21_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjfK family protein"
                     /protein_id="HDV1987267.1"
                     /translation="MSGFFQRLFGKDNKPAIARGPLGLHLNSGFTLDTLAFRLLEDEL
                     LIALPGEEFTVAAVSHIDLGGGSQIFRYYTSGDEFLQINTTGGEDIDDIDDIKLFVYE
                     ESYGISKESHWREAINAKVMGAMILNWQEKRWQRFFNSEEPGNIEPVYMLEKVENQNH
                     AKWEVHNFTMGYQRQVTEDTYEYLLLNGEESFNDLGEPEWLFSRALGVDIPLTSLHII
                     G"
     gene            1772..2170
                     /locus_tag="RHX21_002089"
     CDS             1772..2170
                     /locus_tag="RHX21_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF350 domain-containing protein"
                     /protein_id="HDV1987268.1"
                     /translation="MHILDSLLAFSAYFFIGVAMVIIFLFIYSKITPHNEWQLIKNNN
                     TAASLAFSGTLLGYVIPLSSAAINAVSIPDYFAWGGIALVIQLLVFAGVRLYMPALSE
                     KIINHNTAAGMFMGTAALAGGIFNAACMTW"
     gene            2180..2818
                     /locus_tag="RHX21_002090"
     CDS             2180..2818
                     /locus_tag="RHX21_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1190 domain-containing protein"
                     /protein_id="HDV1987269.1"
                     /translation="MARKRKSRNNSKIGHGAISRIGRPHNPFEPRRNRYAQKYLTLVL
                     MGGAVFLIVKGWSESSDVDNDGDGTFYSTVQDCIDDGNNADICARGWNNAKAAFYADV
                     PKNMTQQNCQSKYENCYYDNVEQSWIPVISGFLLSRVIRKDRDEQFVYNSGGSSFASR
                     PVWRNTSGDYSWRSGSGKKESYSSGGFTTKKASTVSRGGYGRSSSARGHWGG"
     gene            2821..3984
                     /locus_tag="RHX21_002091"
     CDS             2821..3984
                     /locus_tag="RHX21_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="HDV1987270.1"
                     /translation="MLRHNVPVRRDLDQIAANNGFDFHIIDNEIYWDESRAYRFTLRQ
                     IEEQIEKPTAELHQMCLEVVDRAVKDEEILTQLAIPPLYWDVIAESWRARDPSLYGRM
                     DFAWCGNAPVKLLEYNADTPTSLYESAYFQWLWLEDARRSGIIPRDADQYNAIQERLM
                     SRFSELYSREPFYFCCCQDTDEDRTTVLYLQDCAQQAGQESRFIYIEDLGLGVGGVLT
                     DLDDNVIQRAFKLYPLEWMMRDDNGPLLRKRREQWVEPLWKSILSNKGLMPLLWRFFP
                     GHPNLLASWFEGEKPQIAAGESYVRKPIYSREGGNVTIFDGQNNVVDHADGDYADEPM
                     IYQAFQPLPRFGDSYTLIGSWIVDDEACGMGIREDNTLITKDTSRFVPHYIAG"
     gene            4068..5693
                     /locus_tag="RHX21_002092"
     CDS             4068..5693
                     /locus_tag="RHX21_002092"
                     /EC_number="1.3.8.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418608.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isovaleryl-CoA dehydrogenase"
                     /protein_id="HDV1987271.1"
                     /translation="MHWQTHTVFNQPIPLNNSNLYLSDGALCEAVTREGAGWDSDFLA
                     SIGQQLGTAESLELGRLANVNPPELLRYDAQGRRLDDVRFHPAWHLLMQALCTNRVHN
                     LAWEEDARSGAFVARAARFMLHAQVEAGSLCPITMTFAATPLLLQMLPTPFQDWTTPL
                     LSDRYDSHLLPGGQKRGLLIGMGMTEKQGGSDVMSNTTRTERLEDGSYRLVGHKWFFS
                     VPQSDAHLVLAQTTGGLSCFFVPRFLPDGQRNAIRLERLKDKLGNRSNASCEVEFQDA
                     IGWLLGQEGEGIRLILKMGGMTRFDCALGSHAMMRRAFSLAIYHAHQRHVFGNPLIQQ
                     PLMRHVLSRMALQLEGQTALLFRLARAWDRRADAKEALWARLFTPAAKFVICKRGMPF
                     VAEAMEVLGGIGYCEESELPRLYREMPVNSIWEGSGNIMCLDVLRVLNKQAGVYDLLS
                     EAFVEVKGQDRYFDRAVRRLQQQLRKPAEELGREITHQLFLLGCGAQMLKYASPPMAQ
                     AWCQVMLDTRGGVRLSEQIQNDLLLRATGGVCV"
     gene            complement(5810..6085)
                     /gene="yjfN"
                     /locus_tag="RHX21_002093"
     CDS             complement(5810..6085)
                     /gene="yjfN"
                     /locus_tag="RHX21_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418609.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease activator YjfN"
                     /protein_id="HDV1987272.1"
                     /translation="MKQLLASPSLQLVTYPASATAQSAEFASADCVTGLNEIGQISVS
                     NISGDPQDVERIVALKADEQGASWYRIITMYEDQQPDNWRVQAILYA"
     gene            complement(6234..6563)
                     /gene="bsmA"
                     /locus_tag="RHX21_002094"
     CDS             complement(6234..6563)
                     /gene="bsmA"
                     /locus_tag="RHX21_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313192.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm peroxide resistance protein BsmA"
                     /protein_id="HDV1987273.1"
                     /translation="MVSRKRNSVIYRFASLLLVLMLSACSALQGTPQPAPPVTNHPQE
                     IRRDQTQGLQRIGSVSTMVRGSPDDALAEIRAKAVAAKADYYVVVMVDETIVTGQWYS
                     QAILYRK"
     gene            6745..7494
                     /gene="yjfP"
                     /locus_tag="RHX21_002095"
     CDS             6745..7494
                     /gene="yjfP"
                     /locus_tag="RHX21_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HDV1987274.1"
                     /translation="MIEIESRELADIPVLHAYPVGQKDTPLPCVIFYHGFTSSSLVYS
                     YFAVALAQAGLRVIMPDAPDHGSRFSSDEARRLNQFWQILLQSMQEFTTLRAAIAEEN
                     WLLDDRLAVGGASMGAMTALGITARHPTVKCTASMMGSGYFTSLARSLFPPLIPETAA
                     QQNEFNNIIAPLAEWEATNHLEQLGDRPLLLWHGLDDDVVPADESLRLQQALSETGRD
                     KLLTCSWQPGVRHRITPEALDAAVTFFRQHL"
     gene            complement(7491..8246)
                     /gene="ulaR"
                     /locus_tag="RHX21_002096"
     CDS             complement(7491..8246)
                     /gene="ulaR"
                     /locus_tag="RHX21_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator UlaR"
                     /protein_id="HDV1987275.1"
                     /translation="MTEAQRHQILLEMLAQLGFVTVEKVVERLGISPATARRDINKLD
                     ESGKLKKVRNGAEAITQQRPRWTPMNLHQAQNHDEKVRIAKAASQLVNPGESVVINCG
                     STAFLLGREMCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSEN
                     SLYAGHWMFTSGKGLTAEGLYKTDMLTAMAEQKMLSVVGKLVVLVDSSKIGERAGMLF
                     SRADQIDMLITGKNANPEILQQLEAQGVSILRV"
     gene            complement(8354..9418)
                     /gene="ulaG"
                     /locus_tag="RHX21_002097"
     CDS             complement(8354..9418)
                     /gene="ulaG"
                     /locus_tag="RHX21_002097"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003856017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HDV1987276.1"
                     /translation="MSKVKSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLG
                     CTGIWLKSEGGTNVCVDFWCGTGKQSHGNPLMKQGHQMQRMAGVKKLQPNLRTTPFVL
                     DPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPKTCVDLWIGWGVPKER
                     CIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDDRAVNYLFKTPG
                     GSLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADMLRMGEALNAKV
                     VIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHY
                     PRGFDDCFTIEPDLPFKSFL"
     gene            9773..11170
                     /gene="ulaA"
                     /locus_tag="RHX21_002098"
     CDS             9773..11170
                     /gene="ulaA"
                     /locus_tag="RHX21_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418614.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDV1987277.1"
                     /translation="MEILYNIFTVFFNQVMTNAPLLLGIVTCLGYILLRKSVSVIIKG
                     TIKTIIGFMLLQAGSGILTSTFKPVVAKMSEVYGINGAISDTYASMMATIDRMGDAYS
                     WVGYAVLLALALNICYVLLRRITGIRTIMLTGHIMFQQAGLIAVTLFIFGYSMWTTII
                     CTAILVSLYWGITSNIMYKPTQEVTDGCGFSIGHQQQFASWIAYKVAPFLGKKEESVE
                     DLKLPGWLNIFHDNIVSTAIVMTIFFGAILLSFGIDTVQAMAGKVNWTVYILQTGFSF
                     AVAIFIITQGVRMFVAELSEAFNGISQRLIPGAVLAIDCAAIYSFAPNAVVWGFMWGT
                     IGQLIAVGILVACGSSILIIPGFIPMFFSNATIGVFANHFGGWRAALKICLVMGMIEI
                     FGCVWAVKLTGMSAWMGMADWSILAPPMMQGFFSIGIAFMAVIIVIALAYMFFAGRAL
                     RAEEDAEKQLAEQSA"
     gene            11186..11491
                     /gene="ulaB"
                     /locus_tag="RHX21_002099"
     CDS             11186..11491
                     /gene="ulaB"
                     /locus_tag="RHX21_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIB"
                     /protein_id="HDV1987278.1"
                     /translation="MTVRILAVCGNGQGSSMIMKMKVDQFLTQSNIDHTVNSCAVGEY
                     KSELSGADIIIASTHIAGEITVTGNKYVVGVRNMLSPADFGPKLLEVIKEHFPQDVK"
     gene            11501..11965
                     /gene="ulaC"
                     /locus_tag="RHX21_002100"
     CDS             11501..11965
                     /gene="ulaC"
                     /locus_tag="RHX21_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIA"
                     /protein_id="HDV1987279.1"
                     /translation="MKLRDSLAENKSIRLQAEANTWQEAVKIGVDLLVAADVVEPRYY
                     QAILDGVEQFGPYFVIAPGLAMPHGRPEEGVKKTGFSLVTLKKPLEFNHDDNDPVDIL
                     ITMAAVDANTHQEVGIMQIVNLFEDEENFDRLRACRTEQEVLDLIDRTNAAA"
     gene            11979..12629
                     /gene="ulaD"
                     /locus_tag="RHX21_002101"
     CDS             11979..12629
                     /gene="ulaD"
                     /locus_tag="RHX21_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HDV1987280.1"
                     /translation="MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGV
                     RAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVA
                     KEFNGDVQIELTGYWTWEQAQQWRDAGIQQVVYHRSRDAQAAGVAWGEADITAIKRLS
                     DMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAASPVEAARQFKRSIAELWG"
     gene            12639..13493
                     /gene="ulaE"
                     /locus_tag="RHX21_002102"
     CDS             12639..13493
                     /gene="ulaE"
                     /locus_tag="RHX21_002102"
                     /EC_number="5.1.3.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase UlaE"
                     /protein_id="HDV1987281.1"
                     /translation="MLSKQIPLGIYEKALPAGECWLERLRLAKTLGFDFVEMSVDETD
                     ERLSRLDWSREQRLALVNAIVETGVRVPSMCLSAHRRFPLGSEDDAVRAQGLEIMRKA
                     IQFAQDVGIRVIQLAGYDVYYQEANNETRRRFRDGLKESVEMASRAQVTLAMEIMDYP
                     LMNSISKALGYAHYLNNPWFQLYPDIGNLSAWDNDVQMELQAGIGHIVAVHVKDTKPG
                     VFKNVPFGEGVVDFERCFETLKQSGYCGPYLIEMWSETAEDPAAEVAKARDWVKARMA
                     KAGMVEAA"
     gene            13493..14179
                     /gene="ulaF"
                     /locus_tag="RHX21_002103"
     CDS             13493..14179
                     /gene="ulaF"
                     /locus_tag="RHX21_002103"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase UlaF"
                     /protein_id="HDV1987282.1"
                     /translation="MQKLKQQVFEANMELPRYGLVTFTWGNVSAIDRERGLVVIKPSG
                     VAYETMKAADMVVVDMSGKVVEGEYRPSSDTATHLELYRRYPSLGGIVHTHSTHATAW
                     AQAGLAIPALGTTHADYFFGDIPCTRGLSEEEVQGEYELNTGEVIIETLGDAEPLHTP
                     GIVVYQHGPFAWGKDAHDAVHNAVVMEEVAKMAWIARSINPQLNHIDSFLMNKHFMRK
                     HGPNAYYGQK"
     gene            complement(14308..14583)
                     /locus_tag="RHX21_002104"
     CDS             complement(14308..14583)
                     /locus_tag="RHX21_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDV1987283.1"
                     /translation="MFSRVLALLAVLLLSANTWAAIEINNHQARNMDDMQSLGVIYIN
                     HNFATESEARQALNEETDAQGATYYHVILMREPGSNGNMHASADIYR"
     gene            14910..15305
                     /gene="rpsF"
                     /locus_tag="RHX21_002105"
     CDS             14910..15305
                     /gene="rpsF"
                     /locus_tag="RHX21_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020456251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HDV1987284.1"
                     /translation="MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGR
                     RQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPM
                     VKAKDERRERRDDFANETADDAEAGDSEE"
     gene            15312..15626
                     /gene="priB"
                     /locus_tag="RHX21_002106"
     CDS             15312..15626
                     /gene="priB"
                     /locus_tag="RHX21_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N"
                     /protein_id="HDV1987285.1"
                     /translation="MTNRLVLSGTVCRTPLRKVSPSGIPHCQFVLEHRSVQEEAGFHR
                     QAWCQMPVIVSGHENQAITHSITVGSRITVQGFISCHKAKNGLSKMVLHAEQIELIDS
                     GD"
     gene            15631..15858
                     /gene="rpsR"
                     /locus_tag="RHX21_002107"
     CDS             15631..15858
                     /gene="rpsR"
                     /locus_tag="RHX21_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HDV1987286.1"
                     /translation="MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRI
                     TGTRAKYQRQLARAIKRARYLSLLPYTDRHQ"
     gene            15900..16349
                     /gene="rplI"
                     /locus_tag="RHX21_002108"
     CDS             15900..16349
                     /gene="rplI"
                     /locus_tag="RHX21_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HDV1987287.1"
                     /translation="MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNI
                     EFFEARRAELEAKLAEVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADA
                     VTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE"
     gene            complement(16461..17432)
                     /locus_tag="RHX21_002109"
     CDS             complement(16461..17432)
                     /locus_tag="RHX21_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001422748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HDV1987288.1"
                     /translation="MKIKVSAGIIGAVLMLSASQSWAVTLKLSHNQDKSHPVHKAMEF
                     FAKKSKEYSNGDITIRIYPNGTLGTQRETMELIRSGAIPLVKTNAAEMEAFENSYKLF
                     SLPYLFRDRDHYYQVMQGDIGRKILDSTKSKGYFGLTFYDGGARSFYGNKPVLKPDDL
                     KGMKVRVQPSPGAVEMIKVMGGNPTPLDYGELYTALQQGVVDMAENSVMALTTMRHGE
                     VAKSFSLDEHTMVPDVVLMSNAAFDKLSPENQAVILKAAKESMSYMKDLWSEEEKQEF
                     AKLDKMGVKVYQVDKAPFIEKVQPMYANFAKDNPALAPMLADIQAAK"
     gene            complement(17485..18786)
                     /locus_tag="RHX21_002110"
     CDS             complement(17485..18786)
                     /locus_tag="RHX21_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HDV1987289.1"
                     /translation="MDYWLPIIVLFGAFFFMLALGVPIVYAIGLSTLASISTQLDFNS
                     ALSVVSQKLASGLDSFTLLAIPFFILSGNIMNHGGIARRLINFARILGGRLPGSLAHC
                     NILANMLFGAISGSAVASAAAMGGVMHPQQVKEGYDPAFSTAVNVASAPTGLLIPPSN
                     TLIVYSLVSGGTSIAALFLAGYVPGILLGLALMVIAGIIAVRRGYPKPERPTLRQAGV
                     AIWMAISSIFLIVLIMGGVLSGIFTPTEASAIAVIYTLFLALVLYREISVKDLPKIFL
                     ESVITTAIVLLLIGSSMGMSWAMSNADVPFLILDLLNTISDNPIIILLIINIILLIIG
                     TFMDMTPAVLIFTPIFLPVVTELGMDPIHFGIVMVLNMCIGICTPPVGSVLFVGCSVS
                     KLPINKIIKPMLPFYAVMVLVLAMVTYIPQISMALPRALGY"
     gene            complement(18829..19305)
                     /locus_tag="RHX21_002111"
     CDS             complement(18829..19305)
                     /locus_tag="RHX21_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012311688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HDV1987290.1"
                     /translation="MRNIIRSINALLAALNITILAIIVACVTWQVAARFIFTSPSIFT
                     DELSRLLFICLGLFGGAYTAGQNRHLAIDLLPMMLKGKARRHLFLCIQIIVIIFATII
                     MVYGGGLLTMDTFDSGQTSPALGWQMGYIYMSIPISGVLIIIYTIDMVLTELKQPL"
     gene            complement(19326..21407)
                     /locus_tag="RHX21_002112"
     CDS             complement(19326..21407)
                     /locus_tag="RHX21_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005766390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HDV1987291.1"
                     /translation="MSQLDDTILDALTHVTFPKGFAQAEPAWVVTVDGVDYPLWQTDA
                     LVVGSGAAGLRAAVELKRRQQNVLIATAGLYMGTSACSGSDKQTLFTAATAGNGDNFT
                     KLAEALASGGAMDHDTAYVEAVGSLHTLGGLQYLGLELPEDRYGAILRYQTDHDEAGR
                     ATSCGPRTSRLMVKVLLEEVQRLAIPVLTSATVIKLLHQRDENGEDRVAGAILATGHR
                     AHNPWGLAIVTAPNVVLATGGPGELYRDSVYPHKCFGSLGLALEEGLTLTNLTESQFG
                     IGTPRSTFPWNLSGTYVQVIPYIYSVDAEGNEYNFLADYYRTTQELASNIFRKGYQWP
                     FHATRVMDFGSSLLDMAVAQEQQSGRQVFMDFNRNPEAVPGDLPFSLDRLDDDVRAYL
                     ENNDALAPSPIERLQRMNPLSISLYKMHGYDLTTQPLQFAMNNQHMNGGIEVDIWGQT
                     SLPGCFAVGEVAGTHGVTRPGGAALNAGQVFAVRLARFIGCTQKRNIDGDIAQLVAPT
                     LASIREIITQAHDNGTGMPLSVVREKIQARMSDHAGFICHADKVRRATRDALLLSEFV
                     QRHGLAIKHVGEVAELFMWRHMALTSAAVLTQLTHYIDAGGGSRGARIILDRDGNSIP
                     QTRNGFCDAWRFRSERTEDKKDKLLIHYCNGIFHVRETPVREFPIIRGIWFEKNWPGF
                     LNGTIYQPQDE"
     gene            complement(21404..22945)
                     /locus_tag="RHX21_002113"
     CDS             complement(21404..22945)
                     /locus_tag="RHX21_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl CoA:acetate/3-ketoacid CoA transferase"
                     /protein_id="HDV1987292.1"
                     /translation="MRKITTAEALAAQIQDGATIAISGNGGGMVEADHILAAIEARFL
                     QTGHPRDLTLIHSLGIGDRDCKGTNRFAHAEMLKRIIAGHFTWSPKMQALVKNNTIEA
                     YCFPGGVIQALLREIGAGRPGLFTHVGLGSFVDPRNGGGKSNECTTDDLVELIEIDGE
                     TKLRYRPFKVDYAILRGTYADPRGNVSLEEEAIDMDSYSMALAAHNSGGKVFVQVRDV
                     LEAGAIEPRRVKLPGILVDGIVEHREQPQTYLGGYDLTISGQHRRLSSNDAIELVSHP
                     VRRLIARRAARELVAGASTNFGFGIPGGIPGVALREGVPYQSLWLSVEQGVHNGMMLD
                     DAFFGCARNADAIIPSLDQFEFYSGGGIDITFLGMGEMDQYGNVNVSHLNGNLIGPGG
                     FLEIAQNARKVVFCGTFDAKGSKIDVTPDGLHITQSGQIPKLVTQVEKITFSAAYAQQ
                     SGQEVLYITERAVFQLTAEGVELIEIAPGVEIERDILPYMAFRPIIKHPRLMESSLFT
                     PMEDA"
     gene            complement(22955..23731)
                     /locus_tag="RHX21_002114"
     CDS             complement(22955..23731)
                     /locus_tag="RHX21_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HDV1987293.1"
                     /translation="MSDQPVLFSRVAASCRLTLNREDKCHAINEEMIESLDHYLNEIE
                     NDTTLRLVELTATGDKFFCAGGDIKSWSAYSPLDMGRKWIKRGNDVFNRLRNLPQLTV
                     ANLNGHTIGGGIELALCCDIRIARPGAKFSNPEVMLGMVPGWMGIERVLNQVGPVVGR
                     QMLMLGKRLTAQEAQAANLIDEVVEIEQVESWMANQLAQLEKCGPVALAHIKQLILAL
                     ENKHADYPHQLLAGLMSATQDCQQATRAFAEKSSVSFHNQ"
     gene            complement(23741..24583)
                     /locus_tag="RHX21_002115"
     CDS             complement(23741..24583)
                     /locus_tag="RHX21_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDV1987294.1"
                     /translation="MRDLLQRPDLFSINTATLGYKTPLPAIIDACAARGIGAIAPWRR
                     ELQGEDLQQIARQLAASKMNVSGLCRSTYYTAPTLAERKLAIDDNRRALDDAAVLNAA
                     CYMQVVGGLPTGTKDLYEAREQVKQGIRQLLPHSKDVGVPIALEPLHPMTAADRSCLC
                     TLRQALDWCDELDPDGEFGLGVAVDVYHVWWDPDLASQILRAGKRILAFHVSDWLVPT
                     TDLVNDRGMPGDGVINIPSIRRLVENAGFNGAIELEIFSPYWWQKDINSTLDISVDRI
                     AHYC"
     gene            complement(24593..25384)
                     /locus_tag="RHX21_002116"
     CDS             complement(24593..25384)
                     /locus_tag="RHX21_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709993.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-ketoacyl-ACP reductase"
                     /protein_id="HDV1987295.1"
                     /translation="MKSTRPVAVITGAARGIGKGCALELARGGFNLLINDRPDADSVE
                     KLHITQQECLAEGVEVICFPADVGDLSLHEEMLDAAQNQWGRLDCLLNNAGISVKKRG
                     DLLDLEPDSFDQNIAINTRAPFFLAQAFSKRLLAQPKPEAELPHRSIIFVSSINAIML
                     AMNRGEYTIAKTAVSAAARLFAARLCNEQIGVYEVRPGLIKTDMTIPATAYYDELIAK
                     GLVPWGRWGYPADIASTVRAMAEGKLIYTCGQAVAIDGGLSMPRF"
     gene            25594..26232
                     /locus_tag="RHX21_002117"
     CDS             25594..26232
                     /locus_tag="RHX21_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002431731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HDV1987296.1"
                     /translation="MYLDTSHAQNLKEKLLLCAVNEFAEYGYEGARVDNIVKAAGCSK
                     QTVYHHFGNKENLFIEVLEYTWNDIREKERELDISGLSPVIAIEKIIDFTWDYYINNP
                     WFLKIVHSENQSKGVHYKKSKRLAEINHAHLQSMASLLEEGQRQKTFKKDIDPLQINI
                     NIAALGAYYLINQYTLGMVYHISMVSPEALEARRRVIKETILSWLLVNPARG"
     gene            complement(26233..26862)
                     /locus_tag="RHX21_002118"
     CDS             complement(26233..26862)
                     /locus_tag="RHX21_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418627.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OapA family protein"
                     /protein_id="HDV1987297.1"
                     /translation="MPGRFELKPTLVKIWHAPDNFRLMDPLPPMHRRGIIIAAIVLII
                     GILLPGDETRQMPVVTREAQLDMQSPPPGEAQLQAHLVTPQNDPDQVAPVAPEPIQEG
                     QPEEPPVAETQSFQPESGIDQQWRTYRVEPGKTLAQLFRDHNLPPTDVYAMAQVEGAD
                     KPLSNLQNGQIVKIRQNANGVVTGLTIDTENNQQVLFTRQPDGNFIRAR"
     gene            27081..27701
                     /gene="fklB"
                     /locus_tag="RHX21_002119"
     CDS             27081..27701
                     /gene="fklB"
                     /locus_tag="RHX21_002119"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015742582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HDV1987298.1"
                     /translation="MTTPTFDTIEAQASYGIGLQVGQQLSESGLEGLLPEALVAGIAD
                     ALEGKHPAVPVDVVHRALREIHERADAVRRQRFQAMAAEGVKYLEENAKKEGVNSTES
                     GLQFRVINQGEGAIPARTDRVRVHYTGKLIDGTVFDSSVARGEPAEFPVNGVIPGWIE
                     ALTLMPVGSKWELTIPQELAYGERGAGASIPPFSTLVFEVELLEIL"
     gene            28010..29422
                     /gene="cycA"
                     /locus_tag="RHX21_002120"
                     /gene_synonym="dagA"
     CDS             28010..29422
                     /gene="cycA"
                     /locus_tag="RHX21_002120"
                     /gene_synonym="dagA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine/D-alanine/glycine transporter"
                     /protein_id="HDV1987299.1"
                     /translation="MVDQVKVVADDQAPAEQSLRRNLTNRHIQLIAIGGAIGTGLFMG
                     SGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFASDLLGPWAGYF
                     TGWTYWFCWVVTGMADVVAITAYAQFWFPDLSDWVASLAVIVLLLTLNLATVKMFGEM
                     EFWFAMIKIVAIVSLIVVGLVMVAMHFQSPTGVEASFAHLWNDGGWFPKGLSGFFAGF
                     QIAVFAFVGIELVGTTAAETKDPEKSLPRAINSIPIRIIMFYVFALIVIMSVTPWSSV
                     VPEKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAPKA
                     FAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVIGAFTMITTVSAILFMFVWTIILC
                     SYLVYRKQRPHLHEKSIYKMPLGKLMCWVCMAFFVFVVVLLTLEDDTRQALLVTPLWF
                     IALGLGWLFIGKKRAAELRK"
     gene            complement(29467..30129)
                     /gene="ytfE"
                     /locus_tag="RHX21_002121"
     CDS             complement(29467..30129)
                     /gene="ytfE"
                     /locus_tag="RHX21_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster repair protein YtfE"
                     /protein_id="HDV1987300.1"
                     /translation="MAYRDQPLGELALSIPRASALFRKYDMDYCCGGKQTLARAAARK
                     ELDVEVIEAELAKLAEQPIEKDWRSAPLAEIIDHIIVRYHDRHREQLPELILQATKVE
                     RVHADKPSVPKGLTKYLTMLHEELSSHMMKEEQILFPMIKQGMGSQAMGPISVMESEH
                     DEAGELLEVIKHTTNNVTPPPEACTTWKAMYNGINELIDDLMDHISLENNVLFPRALA
                     GE"
     gene            complement(30237..31202)
                     /locus_tag="RHX21_002122"
     CDS             complement(30237..31202)
                     /locus_tag="RHX21_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313215.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDV1987301.1"
                     /translation="MISGVLYALLAGLMWGLIFVGPLIVPEYPAMLQSMGRYLALGLI
                     ALPIAWLGRVRLRQLARRDWLTALMLTMMGNLIYYFCLASAIQRTGAPVSTMIIGTLP
                     VVIPVFANLLYSQRDGKLAWGKLAPALICIGIGLASVNIAELNHGLPDFDWARYTSGI
                     VLALVSVVCWAWYALRNARWLRENPDKHPMMWATAQALVTLPVSLIGYLVACYWLNTQ
                     TPDFSLPFGPRPLVFISLMIAIAVLCSWVGALCWNVASQRLPTVILGPLIVFETLAGL
                     LYTFLLRQQMPPLMTLSGIALLVIGVVIAVRAKPEKPLTESVSES"
     gene            complement(31311..32171)
                     /gene="qorB"
                     /locus_tag="RHX21_002123"
     CDS             complement(31311..32171)
                     /gene="qorB"
                     /locus_tag="RHX21_002123"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H:quinone oxidoreductase"
                     /protein_id="HDV1987302.1"
                     /translation="MIAITGATGQLGHYVIESLMKTVPASQIVAIVRNPAKAQALTAQ
                     GITVRQADYGDEAALTSALQGVEKLLLISSSEVGQRAPQHRNVINAAKAAGVKFIAYT
                     SLLHADKSPLGLADEHIETEKMLADSGIVYTLLRNGWYSENYLASAPAALEHGVFIGA
                     AGDGKIASATRADYAAAAARVISEAGHEGKVYELAGDSAWTLTQLAAELTKQSGKQVT
                     YQNLSEADFAAALKSVGLPDGLADMLADSDVGASKGGLFDNSKTLSKLIGRPTTTLAE
                     SVSHLFNVNN"
     gene            32259..32639
                     /locus_tag="RHX21_002124"
     CDS             32259..32639
                     /locus_tag="RHX21_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418633.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDV1987303.1"
                     /translation="MSQVSLSQQLKEGNLFAEQCPSREVLKHVTSRWGVLILVALREG
                     THRFSDLRRKIGGVSEKMLAQSLQALEQDGFLNRIAYPVVPPHVEYSLTPLGEQVSEK
                     VAALADWIELNLPEVLAVRDERAA"
     gene            complement(32768..34711)
                     /gene="cpdB"
                     /locus_tag="RHX21_002125"
     CDS             complement(32768..34711)
                     /gene="cpdB"
                     /locus_tag="RHX21_002125"
                     /EC_number="3.1.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2',3'-cyclic-nucleotide 2'-phosphodiesterase"
                     /protein_id="HDV1987304.1"
                     /translation="MIKFSATLLATLIAASVNAATVDLRIMETTDLHSNMMDFDYYKD
                     TATEKFGLVRTASLINDARNEVKNSVLVDNGDLIQGSPLADYMSAKGLKAGDIHPVYK
                     ALNTLDYTVGTLGNHEFNYGLDYLKNALAGAKFPYVNANVIDARTKQPMFTPYLIKGT
                     EVVDKDGKKQTLKIGYIGVVPPQIMGWDKANLSGKVTVNDITETVRKYVPEMREKGAD
                     VVVVLAHSGLSADPYKVMAENSVYYLSEIPGVNAIMFGHAHAVFPGKDFADIEGADIA
                     KGTLNGVPAVMPGMWGDHLGVVDLQLSNDSGKWQVTQAKAEARPIYDIANKKSLAAED
                     SKLVETLKADHDATRQFVSKPIGKSADNMYSYLALVQDDPTVQVVNNAQKAYVEHYIQ
                     GDPDLAKLPVLSAAAPFKVGGRKNDPASYVEVEKGQLTFRNAADLYLYPNTLIVVKAS
                     GKEVKEWLECSAGQFNQIDPNSTKPQSLINWDGFRTYNFDVIDGVNYQIDVTQPARYD
                     GECQMINANAERIKNLIFNGKPIDPNAMFLVATNNYRAYGGKFAGTGDSHIAFASPDE
                     NRSVLAAWIAEESKRAGEIHPAADNNWRLAPITGDKKLDIRFETSPSDKAAAFIKDKG
                     QYPMNKVATDDIGFAIYQVDLSK"
     gene            34901..35641
                     /gene="cysQ"
                     /locus_tag="RHX21_002126"
     CDS             34901..35641
                     /gene="cysQ"
                     /locus_tag="RHX21_002126"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'(2'),5'-bisphosphate nucleotidase CysQ"
                     /protein_id="HDV1987305.1"
                     /translation="MLDQVCQLARNAGDAIMQVYDGTKPMDVVSKADNSPVTAADIAA
                     HTVIMDGLRTLTPDIPVLSEEDPPGWEVRQHWQRYWLVDPLDGTKEFIKRNGEFTVNI
                     ALIDHGKPILGVVYAPVMNVMYSAAEGKAWKEECGVRKQIQVRDARPPLVVISRSHAD
                     AELKEYLQQLGEHQTTSIGSSLKFCLVAEGQAQLYPRFGPTNIWDTAAGHAVAAAAGA
                     HVHDWQGKPLDYTPRESFLNPGFRVSIY"
BASE COUNT         8658 a         8843 c         9227 g         8976 t
ORIGIN      
        1 gagagcgcat taattattaa aatgaatgat tatggcgatt tgcaaatcaa tattcttttt
       61 acttcccgcc aaatgattat cgaaaccttt atttgtccgg taagtagtat cagcaatcca
      121 gatgaattta ataccttctt attaagaaat cagaagatga tgccgttgtc atcggtagga
      181 atctccagcg tgcaacagga agagtattac attgttttcg gggcgttatc gcttaaatct
      241 tctcttgaag atatcctgct tgagataacc tcgctggtag ataacgcatt ggatctggct
      301 gaaattacag aagaatattc acactaatta caaggacggg tatttatggg aattttaaaa
      361 agtttattta cgctggggaa atcgtttatc tcccaggcgg aagaatccat tgaagaaacc
      421 cagggcgtgc gcatgctgga acagcatatt cgtgacgcta aagctgaact cgataaagcc
      481 ggaaaatctc gcgttgatct gctggcgcgg gtgaaattaa gtcacgataa gctgaaagat
      541 ttacgtgagc gcaaagccag tctggaagcc cgtgcgctgg aagcgttaag caagaacgtt
      601 aatccgtcgt tgattaacga agttgctgaa gaaatcgcgc gccttgagaa tctcattacc
      661 gctgaagagc aagtgttgtc gaatctggaa gtctcccgtg atggcgtgga aaaagcagtt
      721 acagcgacag cgcagcgtat cgctcagttt gagcagcaaa tggaagtcgt taaagccact
      781 gaagccatgc agcgtgcaca acaggctgta acaacctcta ccgttggcgc atcttccagc
      841 gtttcgacag cggcagaatc cttaaaacgc ctgcaaacgc gtcaggccga acgtcaggct
      901 cgcctggatg ctgctgcaca gttggaaaaa gtcgcagacg gtcgcgatct tgatgaaaag
      961 ctggcggaag ccggaattgg cggtagcaat aaaagtagcg cccaggatgt attagcaaga
     1021 ctgcaacgcc aacagggcga gtaatttttt tgccagcctc gctaaaaggc tggcaactat
     1081 tttaaggata aaatatgtct ggttttttcc agcgtctgtt tggcaaggat aataagcctg
     1141 ctatcgctcg cggtccgctg ggacttcatc tcaatagtgg ctttacgctc gacacgttag
     1201 cgtttcgttt gctggaagat gaattgctga ttgcgctgcc gggtgaggaa tttacggtag
     1261 ccgctgtcag ccacatcgat ctgggcggcg gtagtcagat tttccgctac tacacttcag
     1321 gcgatgaatt tctgcaaatc aataccaccg gcggcgaaga tattgatgac attgatgata
     1381 tcaagctctt tgtctatgaa gagagctacg gtatcagtaa agagagtcac tggcgcgagg
     1441 cgatcaacgc caaagtgatg ggggcaatga tcttaaactg gcaggaaaaa cgctggcagc
     1501 gattttttaa cagcgaagaa ccgggaaata tcgaacccgt ctacatgctg gaaaaagtag
     1561 aaaatcaaaa ccatgccaaa tgggaggtcc ataattttac catgggctac caacgccaag
     1621 taaccgaaga tacttacgaa tatttgctgt taaatggtga ggaatctttt aacgatctcg
     1681 gcgagccaga gtggttattt tcgcgcgcgt tgggtgtcga tatcccgctg acatcacttc
     1741 atattattgg ttaattacaa ggacgtttac aatgcatata ctggattcac ttcttgcctt
     1801 tagcgcctat ttttttattg gcgtggctat ggtgattatt tttcttttta tctattctaa
     1861 aattacaccg cacaacgaat ggcagttaat caaaaacaat aataccgcgg cttcactggc
     1921 gttcagtggt acattgttag gttacgttat cccattatcc agtgcggcaa tcaatgcggt
     1981 gagtattcca gactatttcg cctggggcgg gattgcactg gtgattcagt tactcgtttt
     2041 tgctggtgtc agactttata tgcccgcatt aagcgaaaaa attattaatc acaataccgc
     2101 agcaggaatg tttatgggaa ccgccgcgct ggctggcggt atttttaacg cagcttgtat
     2161 gacatggtaa tggacgatca tggccagaaa acgcaaatca agaaataaca gtaaaattgg
     2221 tcacggagcg atcagtcgca ttggaagacc gcataatcct tttgagccgc gccgcaatcg
     2281 ctacgcacaa aaatacttaa cgttggtgct aatgggcggt gccgtttttt taatagtcaa
     2341 aggatggagt gaaagtagcg atgtcgataa cgacggcgac ggaacgtttt actcgacagt
     2401 gcaggattgt attgatgacg gtaataatgc cgacatttgc gcgcgtggct ggaataacgc
     2461 caaagcggcg ttttatgccg atgttccgaa gaatatgact cagcagaact gtcagtctaa
     2521 gtatgaaaat tgttactacg acaacgttga acagagttgg atcccggtaa tatctggatt
     2581 tttgttaagc cgggttattc gtaaagatcg cgatgagcag tttgtttata acagcggcgg
     2641 atcctcattt gcttcccgcc ccgtctggcg caacacttcc ggtgattact cctggcgctc
     2701 cggttctggc aaaaaagagt cttactcttc aggcggcttt accaccaaaa aagcgtcaac
     2761 cgtttcgcgc ggcggctatg gtcgttcttc cagcgcccgt gggcattggg gaggctaatc
     2821 atgctgagac acaacgttcc tgtgcgacgg gatctggacc agatcgccgc taacaacggt
     2881 ttcgactttc atatcatcga caatgaaatc tattgggatg agagtcgggc ttaccgtttt
     2941 actctgcgcc agattgaaga gcagatcgaa aaaccgactg cggaactgca tcagatgtgc
     3001 cttgaggtgg tggatcgcgc ggttaaagac gaagagatcc tgacgcaact ggcgatcccg
     3061 ccgttgtact gggatgtgat cgccgaaagc tggcgcgcac gcgatccttc gctgtatggc
     3121 cggatggatt ttgcctggtg tggcaatgcg ccggtgaagc tgctggagta caacgccgat
     3181 acgccgacct cgttgtatga gtcggcttat ttccagtggt tgtggctgga ggatgcccgg
     3241 cgcagcggca ttattccgcg tgatgccgat cagtacaatg ccattcagga acgcctgatg
     3301 tcgcgcttta gtgagcttta cagtcgggaa ccgttttatt tttgctgctg tcaggacacc
     3361 gatgaagaca ggactaccgt gctgtacttg caggactgcg cccagcaggc agggcaggag
     3421 tcgcggttta tctacattga agatctcggt ttgggcgtcg gcggcgtact gaccgatctt
     3481 gatgataatg tcatccagcg tgcatttaag ctgtatccgc tggagtggat gatgcgtgac
     3541 gataacggtc cgctgctgcg caagcgtcgc gagcaatggg tggagccgtt atggaaaagt
     3601 atcttgagta ataaagggct aatgccgctg ctttggcgct tcttccctgg tcatcctaac
     3661 cttcttgcat cctggtttga aggtgaaaaa ccgcagattg ccgctggcga aagctatgtg
     3721 cgtaaaccga tctactcgcg cgaaggcggc aacgtcacca ttttcgacgg tcagaataac
     3781 gtcgttgacc acgctgatgg tgattacgcc gatgaaccga tgatctacca ggcgtttcaa
     3841 cctctgccgc gatttggcga tagctacaca ctcatcggta gctggattgt cgatgatgaa
     3901 gcgtgcggaa tggggatccg tgaagataac acgctgatca ccaaagacac ctctcgtttc
     3961 gttccgcatt acattgctgg ctaagaatgt tttagcaatc tctttctgtc aggaatccat
     4021 ggcagtgacc atactaaagg tgactgccat tgatggaggg agacacagtg cactggcaaa
     4081 ctcacaccgt ttttaatcaa cctataccat taaataacag caacttatac ctgtctgatg
     4141 gcgcgctctg cgaagcggta acgcgtgaag gtgctggctg ggatagcgat tttctagcca
     4201 gtattggtca gcagttagga acggctgaat cccttgaact ggggcggctg gcgaatgtga
     4261 atccgcctga attattgcgc tacgatgcgc aaggacgccg tctggacgat gtgcgttttc
     4321 accccgcctg gcacctgctg atgcaggcgc tatgtaccaa tcgggtgcac aatcttgcct
     4381 gggaagaaga cgctcgctcc ggcgcatttg tggcgcgcgc ggcgcgtttt atgttacatg
     4441 cgcaggttga ggcggggtcg ttatgtccga taaccatgac ctttgccgcc acgccattgt
     4501 tgttacagat gttacccacg ccgtttcagg actggaccac gccgctgctg agcgatcgct
     4561 acgattctca cttattgcca ggtgggcaaa aacgcggttt gttgattggc atgggaatga
     4621 cggaaaagca gggcggttcc gatgtcatga gcaacaccac ccgcacagag cgcctggaag
     4681 atggctctta tcggctggtg gggcataaat ggtttttctc ggtgccgcaa agcgatgcgc
     4741 atctggtgct ggcgcagact acgggcggtt tgtcctgctt ttttgtgccg cgctttttgc
     4801 ctgacgggca acgcaacgcg attcgcctcg agcggctgaa agataagctg ggtaatcgct
     4861 ctaacgccag ctgcgaagtg gagtttcagg atgccattgg ctggttgttg gggcaggaag
     4921 gggaaggaat tcgtctgatc ctgaaaatgg gtgggatgac gcgttttgat tgcgccctgg
     4981 gtagccatgc catgatgcgc cgtgcgttct cgctggcgat ttatcatgca catcaacgcc
     5041 atgtttttgg taatccattg atccaacagc cccttatgcg tcatgtctta agtcgcatgg
     5101 cacttcagct tgaagggcaa acggcgttgc tgtttcgtct tgcgcgagcg tgggaccggc
     5161 gtgccgatgc caaagaagct ctgtgggcgc gtttatttac acctgcggca aaatttgtga
     5221 tctgcaaaag aggtatgccg tttgtggccg aagcgatgga ggtgctgggc ggcattggtt
     5281 attgcgagga gagcgagctg ccgcggcttt accgggagat gccggtaaac agtatttggg
     5341 aaggttccgg caatattatg tgcctggatg tgctgcgcgt tctcaataaa caagcgggcg
     5401 tatacgactt attgtcggaa gcatttgtgg aagtgaaagg gcaggatcgc tattttgatc
     5461 gcgcggttcg tcgtttacag cagcagctgc gtaagccagc tgaagaactg gggcgagaga
     5521 ttactcatca gctattcctg ctgggctgcg gtgcgcaaat gttgaaatat gcctctccgc
     5581 caatggcgca ggcgtggtgt caggtgatgt tagatacgcg cggcggcgta cggttgtcag
     5641 agcagatcca gaatgattta ttgctgcggg cgacgggggg agtgtgtgtg taagcgtata
     5701 cgactgatgc gacgctggtt tcgattaact caatgaaata tgtgaaaatt gtaggccgga
     5761 caaggcgctc gcgccgcatc cggcattgtt catttgctgt agatgacact catgcataca
     5821 ggatcgcctg tacgcgccag ttatcaggct gctggtcttc gtacatggta ataatgcggt
     5881 accatgacgc accttgttca tcggccttta acgccacgat acgttccacg tcctgcggat
     5941 cccctgaaat attgctaact gagatctgac ctatttcatt caggcccgtc acgcagtcag
     6001 cactggcgaa ttctgcagac tgtgccgtgg cgctcgcagg ataagtcact aattgcagcg
     6061 agggtgaggc aagtaattgt ttcatcgtca gctccatttt tcgtttcccc acatgttgca
     6121 gggcattcca tcgcggtaat aaacgcccag gcttccagcc ggtaatttat tgtgcacagg
     6181 taaacgcata gggacgcaaa gcaatgtaaa gctgactatg taagttgtct gatttattta
     6241 cggtacaaaa tggcttgtga ataccactgt cctgtcacga tggtttcgtc caccatgacg
     6301 acaacgtaat aatcagcttt tgcagcgaca gctttcgctc tgatttctgc taaagcgtca
     6361 tccggagaac cccgaaccat cgtgcttacg ctacctattc gctgtaaccc ttgcgtctgg
     6421 tcgcggcgaa tctcttgcgg atggttcgtt actggcggtg ctggctgtgg cgtaccttgc
     6481 agtgcgctac aggcacttaa catcaacacc aataataaac tggcaaaccg gtaaataacg
     6541 ctattacgtt tcctgctaac catagtgtag tgccttatta atttaacttt gggggaatgt
     6601 tcccgaattg ttacctggta cgcgattttc gaatgaaaac gtgacgaaag cgtaacccac
     6661 atctcaacat tatgaactaa taccgccagc agaaacttgt gctaaggatt tcttcatgtc
     6721 ataccagaca aaaaggagag acagatgatt gaaatagaat cacgcgagct ggcagatatt
     6781 cccgttcttc atgcttatcc tgtcgggcaa aaagataccc cgttaccgtg cgtaattttt
     6841 tatcacggct ttacttcatc cagcctggtg tatagctatt ttgccgttgc gctggcgcag
     6901 gctggtttgc gggtgatcat gccggatgcg cccgatcacg gtagccgttt tagtagcgac
     6961 gaagcgcggc ggttaaatca attctggcaa atcttgctac aaagtatgca ggaattcact
     7021 actttacgtg cggcaatagc cgaagaaaac tggctgcttg atgaccgtct ggcagtcggt
     7081 ggcgcgtcga tgggcgcgat gacggcactg ggaattaccg ctcgccaccc cacggtgaaa
     7141 tgtaccgcca gcatgatggg atcgggctat tttacatcgc tcgcccgttc actgtttcca
     7201 ccgctgatac ctgaaacggc agcacagcag aatgaattca ataacattat cgcgccgctg
     7261 gcagagtggg aagcgacaaa ccacctggaa caacttgggg acagacctct actgctgtgg
     7321 catggcctcg acgatgacgt tgtgcctgcc gacgaatcac tacgtttgca gcaggcctta
     7381 agcgagacgg gacgggataa actgctaacc tgttcatggc agccaggcgt gcgtcaccgc
     7441 attacgcctg aggcgttaga tgctgccgtg acatttttcc gccagcatct ttaaacacgc
     7501 agaatgctga ccccttgcgc ttccagttgt tgcaggattt ccgggttagc atttttgccg
     7561 gtgatcagca tatcgatttg atcggcacgg ctaaaaagca ttcccgcgcg ttcgccaatc
     7621 ttactgctat caaccagtac caccagtttc cctaccacgc tcagcatctt ctgctctgcc
     7681 attgctgtca gcatatcggt tttatacaac ccttctgcgg tcagcccttt tccgctggta
     7741 aacatccagt gcccggcata gagactgttt tcgctgccct gcgggcttaa agtgatggac
     7801 tgacttttgt tgtactgtcc acccataatg atcacgctgt catgttcttg atcgatcagg
     7861 taatttgcca gcggtagata attagtgatg atttgcactg gcttgccaca catttcccgc
     7921 ccaagcagaa acgcggtgga gccgcagttg atgactacgc tttcgcccgg attaaccagc
     7981 tgcgaggctg ctttagcgat acgtactttt tcatcgtgat tctgcgcctg atgcagattc
     8041 atcggcgtcc agcgcgggcg ctgctgggta atagcttctg cgccattgcg cacctttttc
     8101 agtttgccgc tttcgtcaag tttattgata tcgcgtcgcg cagtggcagg cgaaattccc
     8161 agacgctcaa cgactttctc aacggtcaca aagcccaatt gtgcgagcat ttccaggagg
     8221 atttgatgtc tttgtgcttc agtcatgagc tattccgata aaatttgatt tttttagatg
     8281 atatttgaaa tagccaggaa atactacgcc ggatagcgcg aacttctcca cgctatccgg
     8341 tataaacgac agattacagg aatgacttga acggcagatc cggttcaata gtgaagcaat
     8401 catcgaaacc gcgcggatag tggtactcga agttgtcttt atccagcggc caggtaaatt
     8461 tgccgccaac ctgccagata aacggcttga agccatactt cagacgatct tttttcatct
     8521 cccacagcac gcggatctct tgcggatcgg cctggaagtt tgaccagatg tcgtggtgga
     8581 acgggataac cactttcgca ttcagggctt cacccatacg cagcatatcg gcgctggtca
     8641 ttttgtcggt aataccgcgc gggttctcac catacgatcc taacgccaca tcgatctgat
     8701 gttcgttacc gtgcttcgca taatagttag agtagtggga gtcgccgctg tgatacaggg
     8761 agccgccagg cgttttgaac agatagttca ccgcgcgatc gtccatgccg tccggcagta
     8821 cgccagccgc tttttgatcg gcaggcaggg tgatcagtgc agtacggtcg aaagcgtcaa
     8881 gcgcatgaat ttcaatgtct ttcactttta caacatcgcc cggtttgacc acgatgcaac
     8941 gctctttcgg tacgccccag ccaatccaca aatcaacgca ggttttcggt ccaatgaatg
     9001 gtacgtcatc agcacagttc tgcatcacgg cagcagcgac gttaacgtcg atatgatcgt
     9061 tgtgatcgtg agtcgccagt accgcgtcga tctggcgaat cgcaaacgga tcaagaacaa
     9121 acggggtggt gcgtaggttt ggctgcagtt ttttcacgcc agccatgcgc tgcatctggt
     9181 gaccctgttt cattaacggg ttaccgtgac tttgtttgcc agtgccgcac cagaaatcaa
     9241 cgcaaacgtt ggtgccacct tctgatttca accagatccc ggtgcagcct agccaccaca
     9301 tcgcaaatgt gccaggggcg acctgctctt gttcaatttc ttcattcagc cagctacccc
     9361 actccgggaa agtgctcagg atccaggatt ctcgggtgat acttttcact ttactcatcg
     9421 ccatttacct tcatgatagt tcaattcgaa tcaatatgtg attggttttg attaatcctg
     9481 acactatttt ttcaggaagg caatgaccat tttttgactt tttgccaggg aagtggttgt
     9541 tgattttgag tgtggaaaga tttaatggaa tgtgtaattc aattaactaa atgaatttaa
     9601 atgaatagtt gtttcgttgt gtgaatccca ttctatccat gtggaattat ttgcgggtcg
     9661 cgtcacattt aatcataaat aatcttgttg tgattacttt tgaaaattag agtgagtgca
     9721 caacattccg ggtgtgtgga atacccggtt acctcttctt caggagatcg ttatggagat
     9781 cctctacaac atctttaccg tgttttttaa ccaggtcatg accaatgccc cgttgttgct
     9841 gggtattgtg acctgtctgg gctacatcct actgcgcaaa agtgtcagcg ttattattaa
     9901 aggcacgatt aaaaccataa ttggtttcat gttgttgcag gcagggtccg gcatcctcac
     9961 cagcaccttc aaaccggtgg tggcgaaaat gtccgaagtc tacggcatta acggcgcaat
    10021 ttccgatact tacgcgtcga tgatggcaac catcgaccgc atgggcgatg cctatagctg
    10081 ggtaggttac gcggtgttgt tagcgctggc gttgaacatc tgttacgtgc tgctgcgtcg
    10141 cattaccggt attcgtacca tcatgctgac tggtcatatc atgttccagc aggcggggct
    10201 gattgccgtt acgttgttta ttttcggcta ctccatgtgg acgaccatta tctgcacggc
    10261 gattctggtt tcgctctact ggggcattac ctccaacata atgtacaagc cgactcagga
    10321 agtgacggac ggctgcggtt tctccatcgg tcaccagcaa cagtttgcat catggattgc
    10381 ctataaagtt gcgccgttcc tcggcaaaaa agaggaaagc gttgaagacc tcaaactgcc
    10441 aggctggctg aatattttcc acgacaacat cgtctccacg gcgattgtga tgaccatctt
    10501 ctttggtgcc attctgctct ccttcggtat cgacaccgtg caggcgatgg caggcaaagt
    10561 gaactggacg gtgtacatcc tgcaaactgg tttctccttc gcggtggcga tcttcatcat
    10621 cactcagggc gtgcgcatgt ttgtggcgga actctctgaa gcatttaacg gtatctccca
    10681 gcgcctgatc cctggtgcgg ttctggcgat tgactgtgcg gctatctata gcttcgcgcc
    10741 gaacgccgtg gtttggggct ttatgtgggg caccatcggt cagctgattg cggttggcat
    10801 cctggtcgcc tgcggttcct cgatcctgat tattccaggc tttatcccga tgttcttctc
    10861 caacgccacc atcggcgtgt tcgctaacca cttcggtggc tggcgtgcgg cgctgaagat
    10921 ttgtctggtg atggggatga tcgaaatctt tggttgcgtc tgggcggtga aacttaccgg
    10981 tatgagtgcc tggatgggta tggcggactg gtcgattctg gcaccgccga tgatgcaggg
    11041 cttcttctcc atcggtatcg cctttatggc cgtcatcatt gtaattgcac tggcttatat
    11101 gttcttcgct ggccgcgcac tgcgcgcaga agaagatgca gaaaaacaac tggcagaaca
    11161 gtctgcttaa taaggagttt tgattatgac cgtacgtatt ctggctgtgt gtggcaacgg
    11221 acaaggcagt tccatgatca tgaagatgaa agtggaccag tttttaaccc aatcaaacat
    11281 tgaccacacg gtaaacagct gcgcggttgg cgaatacaaa agcgagttga gcggcgcgga
    11341 tatcatcatc gcttctacgc acattgcggg cgaaatcacc gtgaccggca acaaatacgt
    11401 ggttggtgtg cgcaacatgc tctctcctgc cgactttggc ccgaaactgc tggaagtgat
    11461 caaagaacat ttcccgcagg atgtgaagta aggacgcgcc atgaaattac gtgattcgct
    11521 ggctgaaaat aaatccatcc gcctgcaggc cgaagcaaat acctggcagg aagcggtgaa
    11581 aatcggcgtt gacctgctgg tagcggcaga tgtggtagag ccgcgttact accaggcgat
    11641 tctggatggc gttgaacagt ttggtcctta tttcgttatc gctccggggc tggcaatgcc
    11701 gcacgggcgt ccggaagagg gcgttaagaa aaccggtttc tctctggtaa cgctgaaaaa
    11761 gccgctggaa tttaaccacg acgacaacga tccggtggat atcctcatca ccatggcggc
    11821 ggttgatgcc aacactcacc aggaagtggg catcatgcag atcgtcaacc tgtttgaaga
    11881 tgaagagaat ttcgaccgtt tacgcgcctg ccgtaccgag caggaagtac tggatctcat
    11941 tgaccgcacc aacgcggcag cttaagaagg aattgaacat gtcattaccg atgttgcaag
    12001 tcgcgctgga caaccagaca atggatagcg cctacgaaac cactcgcctg attgccgaag
    12061 aagtcgacat tatcgaagtg ggtaccattc tgtgcgtggg cgaaggcgtg cgtgcggttc
    12121 gcgatctgaa agcgctctac ccgcacaaaa tcgtactggc tgacgccaaa attgccgatg
    12181 caggcaaaat cctttcgcgt atgtgcttcg aagccaacgc tgactgggtg accgtgattt
    12241 gttgtgcgga tatcaacacc gccaaaggtg cgctggacgt ggcaaaagag tttaacggcg
    12301 acgtgcagat cgaactgacc ggttactgga cctgggaaca ggcgcaacag tggcgcgatg
    12361 caggtattca gcaggtggtt tatcaccgca gccgtgacgc gcaggccgct ggcgtggcat
    12421 ggggtgaagc cgatatcact gcgatcaaac gtctttccga tatgggcttc aaagtcaccg
    12481 tcaccggtgg cctggcgctg gaagatctgc cgctgttcaa aggcattcca attcatgtgt
    12541 ttatcgccgg tcgcagcatc cgtgatgccg cttctccggt tgaagccgcg cgtcagttca
    12601 aacgttccat cgccgaactg tggggctaag gagcggatat gttgtccaaa caaatcccgc
    12661 ttggcatcta tgaaaaagcg ctccccgccg gggagtgctg gctggaacgc ctgcgactgg
    12721 caaaaacgtt gggcttcgat tttgtcgaga tgtcggtaga tgaaactgac gagcgcctgt
    12781 cgcgcctcga ctggagccgc gagcagcgtc tggcgctggt gaatgcgatt gttgaaaccg
    12841 gcgtgcgtgt gccgtccatg tgcctttctg cccatcgtcg ttttccgttg ggcagcgaag
    12901 atgacgcggt gcgggcgcag gggctggaga ttatgcgtaa agccatccag ttcgcccagg
    12961 acgttggcat tcgcgtgatc cagctggcgg gctatgacgt ttactatcag gaagccaata
    13021 acgaaacgcg tcgtcgtttc cgtgacggcc tgaaagagag cgttgagatg gcaagccgcg
    13081 cgcaggtgac gctggcgatg gagatcatgg attatccgtt gatgaactcc atcagcaagg
    13141 cgctgggtta cgcgcactat ctcaacaacc cgtggttcca gctctacccg gatatcggca
    13201 acctgtcggc gtgggacaac gatgtgcaga tggagttgca ggccggaatc gggcatatcg
    13261 tcgcggtaca tgtgaaagac accaaacctg gcgtcttcaa aaacgtgccg tttggcgaag
    13321 gtgtagtgga tttcgaacgt tgtttcgaaa cgctcaaaca gagtggctat tgcgggccgt
    13381 acctgattga gatgtggagc gaaacggcgg aagacccggc ggcagaagtg gcgaaagcgc
    13441 gtgattgggt gaaagcgcgc atggcgaaag cgggcatggt ggaggcggca taatgcaaaa
    13501 gctaaaacag caggtatttg aagccaacat ggagctgccg cgctacgggc tggtgacctt
    13561 tacctggggc aacgtcagcg ctatcgaccg cgaacgcggg ctggtggtga tcaagcccag
    13621 cggcgttgcc tacgaaacca tgaaagcggc cgatatggtg gtggttgata tgagcggcaa
    13681 ggtggtggaa ggggagtatc gcccatcttc cgacactgcg acgcatctcg aactctaccg
    13741 tcgttacccg tcgcttggcg gcattgtcca tacccactcc actcatgcca ccgcatgggc
    13801 gcaggcgggg ctggcaattc cggcgctagg caccacgcac gccgactact tctttggcga
    13861 tatcccgtgc acgcgcggat taagcgaaga agaggtgcag ggcgagtatg aactgaacac
    13921 cggcgaagtg attatcgaaa cgctgggtga cgccgagccg ctgcatacgc cggggattgt
    13981 ggtgtatcag cacgggccgt tcgcctgggg gaaagatgct cacgatgcgg tgcataacgc
    14041 ggtagtgatg gaagaagtgg cgaaaatggc gtggattgcg cgcagtatta acccacaact
    14101 gaatcacatc gacagcttcc tcatgaataa acacttcatg cgtaagcacg gtcctaacgc
    14161 ttattacggg cagaagtaaa acacgcgctg cggaaatttc cttcttcggg agataactgg
    14221 tctaattccg cagccgtttt tcaaaaaaag ccccctgcga agggggcaaa gcaaactatg
    14281 gcaatgtttc gttggttata cctggtgcta gcgataaata tccgcgctgg cgtgcatatt
    14341 gccgttactc cccggttccc gcatcagaat tacgtggtag tacgttgcgc cctgcgcatc
    14401 tgtttcttca tttaatgcct gacgtgcttc actttcagtg gcgaaattat gattgatata
    14461 aatcacgcct aagctttgca tatcgtccat atttctggcc tggtggttat tgatttcaat
    14521 ggctgcccat gtatttgcac ttagcaaaag cacagccaga agggctaaaa ctcgactgaa
    14581 catagatacc tcctcgacgg ctgactttgt gtgctctcct ctgtgatgat cttctgattt
    14641 aattttaatc aatgataaag aagttgatgg tgaccatttc tgatgcagtt gttcaaaaaa
    14701 acaccatgat gaagtgtgat gaactccaaa tcagcggttt agaggttaat tgcgaaaggg
    14761 gagatttatt tcggctctgc ccttgagttt agcggggcat acaagtacta taacgcgtca
    14821 tttttcagcc gacctttaac acgttccttg cctccccggg attcggctga cccagacagg
    14881 aggctgaata atccgtaagg agcaattcga tgcgtcatta cgaaatcgtt tttatggtcc
    14941 atcctgacca gagcgaacag gttccgggca tgatcgagcg ctacactgct gccatcactg
    15001 gtgcagaagg caagatccac cgtctggaag actggggccg ccgtcagctg gcttacccga
    15061 tcaacaaact gcacaaagca cactacgttc tgatgaacgt tgaagctccg caggaagtga
    15121 tcgatgagct ggaaactacc ttccgcttca acgatgccgt tatccgcagc atggttatgc
    15181 gtaccaagca cgctgttacc gaagcatctc cgatggttaa agcgaaagac gagcgccgtg
    15241 agcgtcgcga tgatttcgca aacgaaaccg ctgatgatgc tgaagctggg gattctgaag
    15301 agtaatttct gatgaccaac cgtctggtgt tgtccggcac cgtgtgcagg actccccttc
    15361 gaaaggtcag tccatcagga attcctcact gccagttcgt gcttgagcat cgttctgtgc
    15421 aggaggaagc cggctttcac cggcaggcat ggtgtcaaat gcccgttatt gttagcggac
    15481 acgaaaacca ggccattact cacagtataa cggtcggcag tcgcataacc gttcaggggt
    15541 tcatttcatg ccacaaggca aagaacggac tgagcaaaat ggttttgcat gccgagcaga
    15601 ttgaattgat agattctgga gactagccat atggcacgtt atttccgtcg tcgcaagttc
    15661 tgccgtttca ccgcggaagg cgttcaagag atcgactata aagatatcgc tacgctgaaa
    15721 aactacatca ccgaaagcgg taagattgtc ccaagccgta tcaccggtac ccgtgcaaaa
    15781 taccagcgtc agctggctcg cgctatcaaa cgcgctcgct acctgtccct gctgccgtac
    15841 actgatcgcc atcagtaatc ggtcacggtc cattaatacg actttgagag gataaggtaa
    15901 tgcaagttat tctgcttgat aaagtagcaa acctgggtag cctgggtgat caggtaaacg
    15961 ttaaagcggg ctatgctcgt aacttcctgg taccgcaggg taaagctgtt ccagctacca
    16021 agaaaaacat tgaattcttc gaagcacgtc gcgctgaact ggaagctaaa ctggctgaag
    16081 ttctggcagc tgctaatgct cgcgctgaga aaatcaatgc actggaaact gttaccatcg
    16141 cgtctaaagc tggcgacgaa ggtaaactgt tcggttccat cggtactcgc gacatcgctg
    16201 acgctgtaac tgcagctggc gttgaagtgg ctaagagcga agttcgtctg ccgaacggcg
    16261 ttctgcgtac cactggcgaa cacgaagtga gcttccaggt tcacagcgaa gtattcgcga
    16321 aagtgatcgt aaacgtagta gctgaataat tcgttattca acgagacgta aaaacgccga
    16381 ccattggtcg gcgttttgct tttgtagcga gcacttgcag atatcgataa gggccacaat
    16441 aagcagccct acgaagataa ttacttagct gcctgaatat cagccagcat tggggcaagg
    16501 gctgggttgt ccttagcgaa gtttgcgtac attggctgta ctttctcgat aaacggagct
    16561 ttatctacct ggtagacttt cacgcccatt ttatccagtt tcgcaaattc ttgtttctct
    16621 tcctcgctcc acaagtcttt catatagctc attgattctt tagctgcttt taatataact
    16681 gcctgatttt ccgggctaag tttatcaaac gcagcattgc tcatcagaac cacatcggga
    16741 accatagtgt gttcgtcaag gctgaaggat tttgccactt caccgtgacg catggtggtc
    16801 agcgccatca cgctgttttc tgccatatcg accacaccct gctgtaaggc tgtatacaac
    16861 tcgccgtaat ccagtggcgt cgggttaccg cccatgactt tgatcatttc aactgcgcca
    16921 gggcttggct ggacacggac tttcatgcct ttcagatcgt ctggtttcag tactggttta
    16981 ttgccataga aactgcgggc gcctccatca taaaaagtca gcccgaaata acctttgctt
    17041 ttcgttgagt cgaggatttt tctcccgata tcgccctgca tgacctgata ataatgatca
    17101 cgatcgcgga acaaataagg caggctaaat aatttatagg aattttcaaa tgcttccatt
    17161 tctgccgcat tggtttttac cagtggaata gcgccagaac gaatcagctc cattgtttct
    17221 cgttgagtac ccaatgttcc atttggataa atacgaatag taatatcacc gttagagtac
    17281 tctttgctct ttttcgcaaa gaactccatc gctttatgaa caggatgaga cttatcctga
    17341 ttatgactca gttttaatgt cactgcccag gactggcttg cggataacat aagaacagca
    17401 ccgataatgc cagcggatac ttttattttc atagatgttc cttttctaat aaatatggcg
    17461 gcaggtgccg ctagtgaatg cgcatcagta acccagtgct cttggcaatg ccatactgat
    17521 ttgcggaata taggtcacca ttgccagcac caataccatc acggcataga atggcagcat
    17581 aggtttgata attttattaa tcggtaattt agatacacta caaccgacaa ataacacact
    17641 gcctacaggc ggagtacaaa taccgataca catgttcagc accatgacaa taccaaagtg
    17701 aatcgggtcc atgcccagtt cggtgacaac cggtaaaaat atcggcgtaa aaatcagtac
    17761 cgccggtgtc atatccataa aagtgccgat aatcaacagg ataatattga taataagcag
    17821 gattattatt gggttgtcag aaatagtgtt aagcaaatcg agaatcagga agggaacgtc
    17881 agcgtttgac attgcccatg acattcccat cgaagaacca attaataaca agacaattgc
    17941 agtggtaata acggattcca gaaatatttt aggtaaatct ttaactgaga tttcacgata
    18001 aagaaccagt gcaaggaaaa gggtataaat taccgcaatt gcggaggctt cggttggagt
    18061 aaaaataccg cttagtacgc cacccataat taacacaatc aggaaaatac tggagatagc
    18121 catccatatc gcaacgccag cctggcgcaa agtcggacgt tctggttttg gataaccgcg
    18181 acgtacagcg ataataccgg ctattaccat cagtgccaga cccagcaaaa tccccggaac
    18241 ataacccgcc aggaacagtg cggcaataga agtaccacca ctgaccagtg aatagacgat
    18301 taacgtatta cttggtggaa taagcaaacc cgtcggggca gaggcaacgt taaccgcagt
    18361 actgaatgcc gggtcgtagc cctctttaac ctgttgcgga tgcatgacgc cgcccatcgc
    18421 agccgccgaa gccacggctg aaccagaaat tgccccgaac agcatattgg cgagaatatt
    18481 acagtgggca agtgagcctg gcagacgacc gccgagaata cgggcaaagt tgattaatcg
    18541 tcgcgctatt cctccatgat tcataatgtt gccagacaag ataaaaaatg ggattgccaa
    18601 caacgtaaaa ctatctaacc cggaggctaa cttttgggaa accacactca atgctgagtt
    18661 gaaatcgagt tgtgtggaaa ttgatgccag tgtcgataaa ccaatggcat aaacaatagg
    18721 tacacctaat gccaacataa aaaagaaggc accaaataac acaataatcg gtaaccagta
    18781 atccataatt tctccattcc tactatggtt ggttgttgtt tgttatcttt agagtggttg
    18841 tttaagttcg gttaaaacca tatctatggt gtatataata ataagtacac cactaatcgg
    18901 gatgctcata tagatatatc ccatttgcca gcctaaagcg ggcgaggtct gacctgaatc
    18961 gaatgtatcc atcgttaata gcccaccacc atataccata atgatggttg cgaagataat
    19021 aacgataatc tgaatacaca aaaataaatg acgtcgggct tttcctttca gcatcatagg
    19081 tagcaggtca atcgccagat gccggttttg ccctgcggtg tatgccccac caaaaagtcc
    19141 aagacaaata aagagcaaac ggctgagttc atctgtaaaa atactggggc tagtaaatat
    19201 aaatcgtgca gccacctgcc acgtcacaca tgccacgatg atcgccaaaa tggtaatgtt
    19261 caatgctgca agcagagcat taatagatct aattatattt cgcatagtga ttaacctttg
    19321 caatatcatt catcctgtgg ctggtaaatt gtcccattaa gaaaaccagg ccagtttttt
    19381 tcaaaccaaa tacctcggat aataggaaac tcacgaacag gtgtttctct gacgtgaaag
    19441 ataccgttgc aataatgaat aagtagttta tcttttttat cctcagtacg ctctgaacga
    19501 aagcgccagg catcacaaaa accatttcgt gtttgcggaa tagaatttcc atccctgtcg
    19561 agaataatac gtgctccccg actaccacca cctgcgtcaa tataatgcgt taattgcgtt
    19621 aatacggcgg cagaagtcag tgccatatgc cgccacataa acagctcggc aacttcaccc
    19681 acatgtttga tagccaatcc atgccgttgg acaaattcgc tcaatagcag ggcatcgcga
    19741 gtggcgcgtc ggactttatc ggcatggcaa ataaatcccg catggtcaga cattcgtgcc
    19801 tgaatttttt ctctcacaac cgacaacggc atcccggtcc cgttatcgtg cgcctgagta
    19861 atgatctctc ttatagaagc cagtgtagga gctaccagct gtgctatatc tccatcaata
    19921 ttccgctttt gcgtgcaacc aataaaacgt gccagacgaa cagcaaaaac ctgcccggca
    19981 ttcaatgctg caccaccagg gcgagtgacg ccgtgtgtgc cagcaacttc ccccacggcg
    20041 aaacagccgg gcagggaggt ttgtccccag atatccactt caatgccgcc attcatatgc
    20101 tgattattca tggcaaactg caaaggctgt gtggtgagat cgtaaccgtg catcttatac
    20161 agcgagatag acagcggatt cattcgttgc agccgttcga tgggcgatgg tgccagagcg
    20221 tcgttatttt ccagatacgc gcgaacgtcg tcgtccagtc gatctaatga gaacggcagg
    20281 tcacccggca ccgcttcagg attgcgattg aaatccataa atacctgacg ccctgattgc
    20341 tgctcttgcg ctactgccat atctaacaag ctggagccaa aatccatcac ccgcgtggcg
    20401 tggaacggcc actgatagcc tttacggaaa atgtttgaag ccagctcctg ggtggtgcga
    20461 tagtaatccg cgaggaagtt atactcgtta ccctcagcat ccacggaata gatatacggg
    20521 atcacctgta cataggtgcc ggataaattc cacggaaacg tgctacgcgg cgtgcctata
    20581 ccaaactggc tttcggtcag attggttagc gtcagacctt cctccagcgc cagccccagc
    20641 gagccgaagc atttatgtgg ataaacactg tcgcgataaa gctcgccagg ccctcctgtt
    20701 gccagtacca cattgggcgc agtcacaatt gccagccccc atgggttatg ggcgcgatga
    20761 ccggtcgcga ggattgcccc tgccacgcgg tcttcgccgt tttcgtcacg ctgatgcagc
    20821 agtttaatca ctgttgcact ggtcaacact ggaatggcga ggcgctgtac ttcttccaac
    20881 agcactttca ccattaacct tgaggtacgc ggcccacacg aggttgcacg cccggcttcg
    20941 tcatggtcgg tttgataacg aagaatcgcg ccatagcgat cttccggtaa ttccagacca
    21001 agatattgca acccgcctag agtgtgcaga gaacctaccg cttcgacata agcggtgtcg
    21061 tgatccatcg ccccaccgct cgccagtgcc tctgccagtt tggtgaagtt gtcgccgttg
    21121 cccgcggtag cggcggtaaa tagtgtctgt ttatcggaac cagaacatgc cgacgtcccc
    21181 atatataacc cggcggtagc gatcagcaca ttttgctggc ggcgtttaag ttcaactgcc
    21241 gcacgtaatc ctgctgcacc actgccgact accagggcat ctgtttgcca gagtgggtaa
    21301 tcaacaccgt ctaccgtgac aacccatgcg ggctctgcct gtgcaaaacc ctttgggaaa
    21361 gtaacgtgcg tcagcgcatc aaggatggtg tcatcaagct gactcatgca tcctccatcg
    21421 gcgtaaacag gctactttcc atcaggcgtg ggtgcttgat aattggacgg aaagccatat
    21481 acggcagaat gtcgcgctca atctccacac ccggcgcgat ttcaattaat tcaacgcctt
    21541 ctgccgttaa ctggaatact gcgcgttcag tgatatacaa cacttcctga ccactttgct
    21601 gtgcgtaggc ggcgctaaaa gtgatttttt ccacctgggt aaccagttta gggatttgac
    21661 ctgactgggt gatatgcaag ccatctggcg ttacatcaat cttgctacct ttggcgtcga
    21721 acgtgccgca gaacaccact ttacgggcgt tttgcgcaat ttcgagaaaa ccgccgggac
    21781 caatgagatt gccattgaga tgggatacgt tgacgttacc gtactgatcc atctctccca
    21841 tgccgaggaa ggtgatatcg attcctccgc cactgtagaa ctcaaattga tcgagtgatg
    21901 gaataatggc atcggcgttg cgggcgcagc cgaaaaacgc atcatccagc atcataccgt
    21961 tatgcacgcc ttgctcgacg ctcagccata aactttggta aggcacgcct tcgcgcagcg
    22021 ctacgcctgg aataccccca ggaataccaa agccaaagtt ggttgaagcg ccagctacca
    22081 gttcgcgtgc cgcccgacgg gcaatcaggc gacgtaccgg atgactaacc agttcaatgg
    22141 cgtcgttaga actcagacgg cgatgttggc cgctgatggt caggtcgtaa ccgccaagat
    22201 aggtttgtgg ttgttcgcgg tgttcaacga tgccatcaac cagaatgccc ggtaatttga
    22261 cccggcgtgg ttcaatcgcg ccagcttcca gcacatcgcg tacctgtacg aacactttgc
    22321 cgccgctgtt gtgtgctgcc agcgccatgg aatagctatc catatcaatc gcttcttctt
    22381 caaggctgac gttgcctcga ggatcggcat aagtgccacg caaaatcgcg taatccactt
    22441 tgaaagggcg ataacgaagt ttggtttcac cgtcgatttc aatcagttct accaggtcgt
    22501 cggtagtgca ttcattcgac ttaccgccgc cattgcgtgg atcaacaaac gatcccagcc
    22561 caacgtgggt aaaaagcccc ggacgtccgg cgccgatctc ccgtagcagt gcctgaatca
    22621 cgccaccagg aaagcagtag gcttcaatcg tgttattttt taccagcgcc tgcattttgg
    22681 gcgaccaggt aaagtgcccg gcaataatgc gtttgagcat ctctgcgtgc gcaaaacggt
    22741 tagtgccttt gcagtcgcga tcgccaatac ccagcgagtg gattagcgtc aggtcgcgag
    22801 ggtgtccggt ttgcaggaaa cgcgcttcaa tagcagccag aatatggtcg gcttccacca
    22861 tgccgccgcc gttaccgcta atggcaatgg ttgcgccgtc ctgaatttgc gccgccagtg
    22921 cctcggcggt tgttatctta cgcatacaat ttccttattg attatggaag ctcacgctac
    22981 ttttttcggc aaaggcgcgc gtcgcctgct ggcaatcctg agtggcggac attaatccgg
    23041 ccagtagctg gtgcgggtaa tcggcatgtt tattttccag tgccagaatc agttgcttaa
    23101 tatgcgccag tgccaccgga ccgcattttt ccagctgcgc taactggttc gccatccagc
    23161 tttccacctg ttctatttct accacttcat caattaaatt cgccgcctgg gcttcctgcg
    23221 ccgtcaggcg tttacccagc atcagcatct ggcgaccgac caccggacca acctgattaa
    23281 gcacacgttc aatgcccatc cagccaggca ccatgccgag catcacttcc gggttagaga
    23341 atttcgcgcc ggggcgggca atacgaatat cgcagcacaa ggccagttca ataccaccgc
    23401 cgatggtatg accgttgaga ttcgcaacgg ttaattgggg taagtttcgc aggcgattaa
    23461 aaacgtcatt accgcgttta atccattttc tgcccatatc taatggcgaa taggccgacc
    23521 acgatttaat atcgccgccc gcacaaaaga atttatcgcc ggttgccgtt aattcgacta
    23581 atcgtaatgt ggtgtcgttt tcaatttcat ttaaataatg gtcgagagat tcgatcatct
    23641 cttcgttaat agcatgacat ttatcttcac ggttcaatgt caggcggcag gaagccgcca
    23701 ctctgctgaa cagaacgggt tggtcactca tgatcattcc ttaacaataa tgcgcgatgc
    23761 gatcgacgct aatatccagc gtgctgttaa tatctttctg ccaccagtaa ggcgagaata
    23821 tttccagttc aatagcacca ttaaatccgg cgttttcaac cagccgacga attgacggaa
    23881 tattgatgac gccatctccc ggcataccac ggtcattgac cagatcagtg gtcggcacta
    23941 accagtcgga aacatgaaac gcgaggatgc gttttccggc acgcaggatc tgactggcga
    24001 gatccgggtc ccaccaaaca tggtagacat ctaccgccac gccgaggcca aattcgccat
    24061 cgggatcgag ttcatcacac cagtccagcg cctgacgtaa cgtgcacaga caggaacgat
    24121 cggctgcggt catcgggtgc agcggctcca gtgcaattgg cacgccgaca tctttcgaat
    24181 gtggcagcaa ctggcgaatc ccttgtttca cttgttcccg cgcttcatat agatctttag
    24241 tgcccgttgg cagaccgcca accacctgca tataacaggc ggcattcagt acagcggcgt
    24301 cgtccagcgc ccggcggtta tcgtcaatcg ccagtttgcg ctccgccagc gtcggtgcgg
    24361 tgtagtaggt gctacggcac aaaccggaaa cgttcatctt actggcggca agctgacggg
    24421 cgatctgctg gagatcttcg ccctgcaact ccctgcgcca gggggcaatt gcgccaatac
    24481 cgcgtgcagc gcaggcatca ataatggcgg gtagcggcgt tttatagccc agtgttgcgg
    24541 tattgatact gaataaatcc gggcgttgta acagatctct catgattcag cctcagaagc
    24601 gcggcatact taagccgccg tcgatggcga ccgcctgacc acaggtgtaa atcagtttac
    24661 cttccgccat cgcgcggacg gtggaagcaa tatcagccgg ataaccccaa cgtccccacg
    24721 gcaccagacc tttggcaatc agttcgtcgt aataagccgt tgccggaata gtcatatcag
    24781 ttttgatgag acctgggcgc acttcataaa cgccaatttg ttcattacaa aggcgagcag
    24841 caaatagacg agcagcggca gaaacggcgg ttttggcaat ggtgtattcg ccgcgattca
    24901 tcgccagcat gatggcgttg atggaactga cgaaaataat cgagcggtgc ggcagttccg
    24961 cttccggttt cggctgtgcc agtaagcgct tactgaatgc ctgagcaagg aagaacggcg
    25021 cgcgggtgtt aatggcaatg ttttgatcga agctgtctgg ttcgaggtcg aggaggtcac
    25081 cgcgtttttt cactgaaatc ccggcgttat tgagcaggca gtccagacgc ccccactggt
    25141 tttgcgccgc gtcgagcatc tcttcatgca aggagagatc gccgacatcg gcagggaagc
    25201 aaatgacttc cacgccttct gccaaacatt cttgttgtgt gatatgcagt ttttctacgc
    25261 tgtcggcatc gggacgatcg ttaatcagca ggttaaaccc gccacgagca agctccagcg
    25321 cacagccctt tccaatacca cgagcggctc cggtaatcac ggcaactgga cgagtggatt
    25381 tcatacaata accctctttt gaatattgtt ttctttagtg atgattagct tgcgactggc
    25441 aggtaaaaag atcaaccatc tagttggttg atctgcgaga gtgatcacag gtaatttgat
    25501 aactcaatga aattacgact tttatccttt ttgctgtcgc tgagatcaaa tccggttatg
    25561 atagccatca cgaagaggaa gtggggaagt ggaatgtatc ttgataccag tcacgcacaa
    25621 aacctgaagg aaaaattgct gctatgtgcg gttaatgaat ttgccgaata tggttatgaa
    25681 ggggccagag tagataatat tgttaaggca gcagggtgta gtaaacagac ggtttatcac
    25741 cactttggta ataaagaaaa tttgtttatt gaagtactgg aatatacctg gaacgatatt
    25801 cgcgaaaaag agagagagct tgacatttca gggctttctc cggttattgc gatcgagaaa
    25861 ataattgatt ttacttggga ttattacatc aataatccgt ggtttttaaa aattgtccat
    25921 agtgaaaacc aaagtaaggg tgtgcattat aaaaaatcaa aacgcctcgc tgaaattaac
    25981 catgcacatt tgcagtcaat ggcttcgtta ttagaagaag ggcagcgaca gaaaaccttt
    26041 aagaaagata ttgatccctt acaaatcaat attaatatcg ccgcactggg tgcatattat
    26101 ttaataaacc agtacacact ggggatggtt tatcacatta gcatggtttc acctgaggct
    26161 ttggaagcca gacgcagagt gatcaaagag accatcctga gctggctttt ggtgaaccct
    26221 gcccgtgggt aatcagcgtg cgcggatgaa attaccatca ggttggcggg tgaacagtac
    26281 ttgctgatta ttttccgtat caatggttaa gccggtaacc accccattcg cattttgacg
    26341 gattttaaca atctgaccat tttgcaggtt actgagcggt ttatccgcgc cctcgacctg
    26401 ggccatagcg tacacatctg taggcggcaa attatggtcg cggaacagct gggcaagggt
    26461 cttgcctggt tctacgcgat atgtccgcca ctgttgatcg ataccacttt ccggttggaa
    26521 agattgtgtc tctgcaacag gtggctcttc aggttgacct tcctgaatag gttccggcgc
    26581 gaccggggcg acctgatccg gatcgttttg cggcgtcact aaatgtgcct gtagctgtgc
    26641 ttcacctggg gggggtgatt gcatatctaa ctgcgcttcg cgggtgacaa caggcatctg
    26701 gcgtgtttca tctccaggca gaagaatacc gataatcagc actattgccg caataatgat
    26761 tccccggcga tgcatcggcg gcaacgggtc catgaggcga aagttatctg gtgcgtgcca
    26821 gattttcacc agagttggtt ttagttcaaa gcgcccaggc atggttttcc tccagctccg
    26881 cgtcgtgttc ctcaatcata gcgcagtaat aagctaacgc tatgatgtcc gtggtattac
    26941 cgctgttttt gtattcatgc ggattatccc tattgtttct gtttccctgg gatttgtcac
    27001 tcatcccgcg acaaagtttt accagaagaa gcgtggctga tatcctgccc gctactttat
    27061 accctaagaa aggaaatacg atgaccaccc caacttttga caccatcgaa gcgcaagcaa
    27121 gctacggcat tggtttgcag gtagggcaac aactgagtga atctggcctg gaagggctgc
    27181 tgccagaagc actggttgca ggtattgccg atgcgctgga aggcaaacat ccggctgttc
    27241 cggttgatgt ggtgcatcgc gcgctgcgtg aaatccacga gcgcgccgat gccgttcgtc
    27301 gtcagcgttt ccaggcgatg gctgctgaag gtgtgaaata cctggaagaa aacgccaaaa
    27361 aagaaggtgt gaatagcacc gaatctggcc tgcaattccg cgtgatcaac cagggtgaag
    27421 gcgcaattcc ggcacgtacc gaccgcgttc gtgttcatta caccggtaaa ctgatcgacg
    27481 gcaccgtgtt tgacagctcc gttgctcgtg gtgaacccgc tgaatttccg gttaatggcg
    27541 tgatccctgg ctggattgaa gcactgactc tgatgccggt aggttctaaa tgggaactga
    27601 ctatcccgca ggaactggca tatggcgagc gcggcgcagg cgcatccatc cctccgttca
    27661 gcaccctggt gtttgaagtc gaactgctgg aaatcctcta agcagcgcat tctgttcccc
    27721 tcgaaccaga ggggagcagg cattcagcaa taaacccttc agtttgccaa acggcgctat
    27781 tttgtgttgc aaagaccccg taagcgtgta tttttgtgag ctgtttcgcg ttatcaccgt
    27841 gatatgacac tcactttaaa cataaaatta acattagatc taaatcttag tattcatccc
    27901 gcgtattgtt acctaatatc gatgagtccc gatacagatt cgtcgtatca tagactgact
    27961 aaaggccgta gagcctgaac aacacagaca ggtacaggaa gaaaaaaaca tggtagatca
    28021 ggtaaaagtc gttgccgatg atcaggctcc ggctgaacag tcgctacggc gcaatctcac
    28081 aaaccgacat attcagctta ttgccattgg cggtgccatt ggtacggggt tgtttatggg
    28141 gtctggcaaa acgattagcc ttgccgggcc gtcgatcatt ttcgtttata tgatcattgg
    28201 ttttatgctc tttttcgtga tgcgggcaat gggggaattg ctgctttcga atctggaata
    28261 caaatctttt agtgacttcg cttccgattt actcgggccg tgggcaggat atttcactgg
    28321 ctggacttac tggttctgct gggttgtaac cggtatggca gacgtggtgg cgatcacggc
    28381 ttatgctcag ttctggttcc ccgatctctc cgactgggtc gcctcgctgg cggtgatagt
    28441 gctgctgctg acgctcaacc ttgccaccgt gaaaatgttc ggtgagatgg agttctggtt
    28501 tgcgatgatc aaaatcgtcg ccatcgtgtc gctgattgtc gtcggcctgg tcatggtggc
    28561 gatgcacttt cagtcaccga ccggtgtgga agcgtcattc gcgcatttgt ggaatgacgg
    28621 cggctggttc ccgaaaggtt taagtggctt ctttgccgga ttccagatag cggttttcgc
    28681 tttcgtgggg attgagctgg taggtacaac agctgcggaa accaaagatc cggagaaatc
    28741 actgccgcgt gcaattaact ctattccgat ccgtatcatt atgttctacg tcttcgcgct
    28801 gattgtaatt atgtccgtga cgccgtggag ttcggtagtc ccggagaaaa gcccgtttgt
    28861 tgaactgttc gtgttggtgg gtttgcctgc ggctgccagc gtgatcaact ttgtggtgct
    28921 gacctctgcg gcgtcttccg ctaacagcgg cgtcttctct accagccgta tgctgtttgg
    28981 tctggcgcag gaaggtgttg cgccgaaagc gttcgctaaa ctttctaagc gcgcagtacc
    29041 cgcgaaaggg ctgacgttct cgtgtatctg tctgctcggc ggcgtggtga tgttgtatgt
    29101 gaatcctagt gtgattggcg cgttcacgat gattacaacc gtttccgcga ttctgtttat
    29161 gttcgtctgg acaattatcc tttgctcgta cctggtgtac cgcaaacagc gtcctcatct
    29221 gcatgagaag tcgatctaca agatgccgct cggcaagctg atgtgctggg tatgtatggc
    29281 gttctttgtg ttcgtggtcg tgttgctgac actggaagat gacactcgcc aggcgctgct
    29341 ggttaccccg ctgtggttta tcgcgctggg gttgggctgg ctgtttattg gtaagaagcg
    29401 ggctgctgaa ctgcggaaat aaccgcatta tcatgctgga tggcgcaatg ccatccagct
    29461 tttagatcac tcacccgcca gcgcgcgtgg gaacagtaca ttgttttcca ggctgatgtg
    29521 atccatcagg tcatcaatca gttcattaat gccgttatac atcgctttcc aggtggtgca
    29581 ggcttccggc ggcggtgtga cgttattggt agtgtgtttg attacttcca gcagttcacc
    29641 cgcttcatcg tgctcgcttt ccattacgct gattggcccc attgcctggc tgcccatgcc
    29701 ttgtttgatc atcgggaaga ggatctgctc ttctttcatc atgtggctgg aaagctcttc
    29761 atgcagcata gtcaggtatt ttgtcagccc ttttggcacg ctcggtttgt cggcgtgaac
    29821 gcgctcgact ttagtcgctt gcaggatcag ctccggcaac tgctcgcggt gacgatcgtg
    29881 gtagcgcacg atgatatggt caatgatttc tgccagcggg gcgctacgcc agtctttctc
    29941 aatcggttgt tcagcgagct ttgctagttc agcttcaatg acctcaacat ccagttcttt
    30001 acgtgccgcc gcgcgcgcca gcgtctgctt accgccacag cagtaatcca tatcatattt
    30061 acgaaacaga gctgaagcgc gaggaataga gagcgccagt tcacctaaag gttggtcgcg
    30121 ataagccata gctgatacct cattcttaat aagataagat gtattttaaa tgcatcttta
    30181 aggcaaaagc tataaccctt acgtagcaga ggcttattta actcactgcc agcgtgtcaa
    30241 ctttctgaga cagattcagt taaaggtttt tctggttttg ctctgaccgc gatgaccacg
    30301 ccaatcacta acagcgcgat accgctcagc gtcattagcg gcggcatttg ctggcggagt
    30361 aaaaaggtgt acagcaaacc tgccagcgtt tcgaaaacaa tcagcggccc gagaatcact
    30421 gtcggtaatc gctggctggc gacgttccag cagagtgcgc caacccatga gcaaagcacg
    30481 gctatcgcaa tcatcagact aataaacacc agcggacggg ggccaaaggg tagggagaag
    30541 tccggcgttt gcgtattcag ccagtaacaa gcgacgagat agccgataag tgaaaccggc
    30601 agtgtgacca gcgcctgcgc tgttgcccac atcatcggat gtttgtcggg attttcccgc
    30661 agccagcggg cgttgcgcag ggcataccac gcccagcaga ccacggaaac taacgctagc
    30721 acgatgccag aggtataacg tgcccagtca aaatcgggga gtccgtggtt taactcagca
    30781 atattcacac tcgcgaggcc gatgccaata caaatcagtg ccggggcgag ttttccccac
    30841 gcgagtttgc cgtcgcgctg gctataaagc agattggcaa agacaggaat gaccaccggc
    30901 agggtgccga taatcatcgt ggaaacaggc gcgccagtac gttgaatggc actggcaagg
    30961 cagaagtaat aaatgaggtt gcccatcata gtgagcatca aggcggtaag ccagtcgcga
    31021 cgcgccaact gacgcagacg cacgcgtccc agccaggcaa tgggcagcgc aattaaccct
    31081 aacgccagat aacgccccat cgactgcaac atcgccgggt attccggtac gatcaacggc
    31141 ccgacaaaaa taagccccca catcaaccct gctaacaggg cgtacagcac gccgctaatc
    31201 attactggca tccattgatc tgtcagaaga aacgttcagg aagcagatat gattgctccc
    31261 ggcatcccgt cattatcaga gaggatgcgg gaggatgcca ctttaattaa ctagttatta
    31321 acattaaaaa gatggcttac gctttcggct aacgttgtcg ttgggcggcc aatcaatttg
    31381 ctaagcgttt tgctgttatc aaacagacca cctttcgatg cgccaacgtc agaatccgcc
    31441 agcatatccg ccagtccgtc aggcagtccg acgcttttca gtgccgcggc gaaatcagct
    31501 tcactcagat tttgataggt aacctgtttg ccgctctgtt tggtcagctc tgccgctaac
    31561 tgtgtcaacg tccaggcact atcgcccgcc agttcgtaaa ccttgccttc gtgaccggct
    31621 tcgctaatca cgcgtgccgc agctgccgca taatctgccc gcgttgctga ggcgattttg
    31681 ccatcgcccg ccgcaccgat aaatacgccg tgttccagtg ctgccggggc gctggcgagg
    31741 tagttttcgc tgtaccagcc gttgcgcagc agggtgtaaa cgatgccaga atcagccaac
    31801 attttctccg tctcaatgtg ctcatcggcg aggccgagcg gagatttatc cgcgtgaagc
    31861 agactggtat aagcgataaa tttcacacca gccgcctttg cggcattaat aacattacga
    31921 tgctgcgggg cacgttgacc cacttcgctg gaagagatca gcagtagttt ttccactccc
    31981 tgaagtgcag atgtcagtgc ggcttcatcg ccgtagtcag cctgacgcac ggtaatgcct
    32041 tgtgctgtca gtgcctgggc ttttgccgga ttacgaacga tagccactat ttggctggca
    32101 ggaaccgttt tcatcaagga ttcaataaca tagtgaccaa gttggccagt ggcaccagta
    32161 attgcgatca taggaagtct ccatcgtttg tcttgtgttt aaatacgcta acacctaaac
    32221 ttacttttag taagtacgta caaaaaggta agtatgagat gagtcaggtt agcctgtcgc
    32281 aacaactgaa agagggaaat ctcttcgctg aacagtgtcc gtcgcgcgag gtgttgaaac
    32341 acgtcaccag ccgttggggg gtgttgattc tggtggcgct acgcgaaggt actcatcgct
    32401 ttagcgacct gcggcgcaaa atcggtgggg tgagtgaaaa gatgcttgcg cagtcgttac
    32461 aggcgttaga acaggatggt tttcttaacc gtatcgcgta tccggtggtg ccgccgcatg
    32521 tggaatatag cctcacgccg ctgggcgagc aggtgagcga aaaggttgct gcactggcgg
    32581 actggattga gttgaatttg cccgaggtgt tagcggtgcg ggatgaacgt gcggcataac
    32641 tgccggatgc gctgagctta tctggtctac ggtgcatggc ttgtagggcg gataagatgc
    32701 gccagcatcg catccgccaa taaatgccgg atgcggttga tgatttgcag gccgaaaaag
    32761 aagtgtatta cttactcaaa tccacctgat aaatcgcaaa cccgatatca tcggtcgcga
    32821 ctttattcat cggatattgc cctttatctt taataaacgc tgcggcttta tctgacggag
    32881 aggtttcgaa acggatatcc agtttcttat cgccagttat cggtgctaaa cgccagttgt
    32941 tatccgccgc cgggtgaatt tcccccgcac gtttcgactc ttcagcaatc cacgctgcca
    33001 gcaccgagcg gttctcatcc ggtgaagcaa aagcgatatg gctgtcgccc gtaccggcaa
    33061 atttgccgcc gtaagcgcga tagttattgg tggcaacgag gaacatggcg ttcggatcaa
    33121 tcggcttgcc gttaaagatc aggttcttaa tcctttccgc attggcatta atcatctggc
    33181 actcgccgtc ataacgggcg ggctgggtaa catcaatctg ataattcaca ccatcaatca
    33241 catcaaagtt ataggtgcgg aaaccatccc agttgatgag tgactgtggt ttcgtgctgt
    33301 taggatcaat ctggttaaac tgtccggcgg agcactccag ccactctttc acctctttac
    33361 cgctggcttt caccacaatc agcgtattgg gatagagata aagatcggcg gcattacgga
    33421 aagtcagctg acctttttcc acctccacat agcttgccgg gtcatttttg cgaccaccaa
    33481 ctttaaacgg tgcggcagct gaaagcaccg gcagttttgc cagatccgga tcgccctgaa
    33541 tgtaatgctc gacatacgct ttttgcgcgt tgttcaccac ctgcacggtc ggatcgtcct
    33601 gcaccagcgc cagatagcta tacatattgt cggcagattt accgattggc ttgctgacga
    33661 actggcgtgt ggcatcgtga tcggctttga gtgtttctac cagcttgctg tcttccgccg
    33721 cgagggattt tttattggcg atgtcgtaaa tcggtcgtgc ttccgctttc gcctgcgtca
    33781 cctgccattt accgctgtca ttactgagtt gtaagtcgac cacaccaaga tgatcgcccc
    33841 acatgcccgg cattaccgcc ggaacaccat tcagcgtgcc tttggcgata tcagcccctt
    33901 cgatatcagc aaaatcttta cccgggaaaa cggcgtgagc atgaccaaac ataatggcgt
    33961 taacacccgg aatttcactg aggtaataaa ctgagttttc cgccatcact ttatacggat
    34021 cggcagacag accagaatgc gccagaacga caacgacatc ggcacctttc tcgcgcattt
    34081 caggcacgta tttgcgcacg gtttcggtaa tatcattcac cgtcactttc ccggataaat
    34141 tagctttatc ccagcccatg atttgtggcg ggacgacgcc aatatagcca atcttcagcg
    34201 tctgtttttt tccgtcttta tcgaccactt cggtgccttt aattaaatac ggtgtaaaca
    34261 ttggctgttt ggttctggcg tcaatgacgt tggcatttac ataagggaat ttcgctcccg
    34321 ccagcgcatt tttcaggtaa tccagaccgt agttaaactc gtggttgcca agcgtgccga
    34381 cggtatagtc cagcgtattt aatgccttat agaccgggtg aatatcacct gcttttaaac
    34441 ctttcgccga catgtaatct gcaagcggac tcccctgaat caaatcgccg ttatcgacca
    34501 gtacgctgtt tttcacttca ttgcgggcat cgttaatcag gcttgcggta cgtaccagtc
    34561 cgaatttttc cgtggcggtg tctttgtaat aatcgaaatc catcatgttg ctatgcagat
    34621 cagtggtttc catgatacgc agatcgaccg tcgctgcatt cacactggcg gcaatcagcg
    34681 tggccaggag cgttgcgcta aacttaatca tcagggacat ccttttatca tcgggaatac
    34741 gaaagaaaag ggagaataaa cgtcttactt atagaacagt gaagaatgcc acaattttac
    34801 gctttgaaaa tgatgacact atcacagttg gcgcattcat taacgatagg gtataagtaa
    34861 aacaataagt taacaccgct cacagagacg aggtggagaa atgttagatc aagtatgcca
    34921 gcttgcacgg aatgcaggcg atgccattat gcaggtctac gacgggacga aaccgatgga
    34981 cgtcgtcagc aaagcggaca attctccggt aacggcagcg gatattgccg cacacaccgt
    35041 tatcatggac ggtttacgta cgctgacacc ggatattccg gtcctttctg aagaagatcc
    35101 tcccggttgg gaagtccgtc agcactggca gcgttactgg ctggtagatc cgctggatgg
    35161 tactaaagag tttattaaac gtaatggcga atttaccgtt aacattgcgc tcatcgacca
    35221 cggcaaaccg attttaggtg tggtgtatgc gccggtaatg aacgtaatgt acagcgcggc
    35281 agaaggcaaa gcgtggaaag aagagtgcgg cgtgcgcaag cagattcagg tccgtgatgc
    35341 gcgcccgccg ctggtggtta tcagccgttc ccatgcagat gcggagctga aagagtatct
    35401 gcaacagctt ggcgaacatc agaccacgtc catcggctct tcgctgaaat tctgcctggt
    35461 ggcggaaggg caggcgcagc tgtacccgcg cttcggacca acgaatattt gggacaccgc
    35521 cgctggacat gctgtggccg cagctgccgg agcgcacgtt cacgactggc agggtaaacc
    35581 gctggattac actccgcgcg agtcgttcct gaatccgggg ttcagagtgt ctatttacta
    35641 aattcagatg gcagaaacag tgtatttcct gattctgcca tcctgatttc tcccaaccta
    35701 aaaa
//
LOCUS       DAPGUL010000040        34870 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.040, whole genome shotgun sequence.
ACCESSION   DAPGUL010000040 DAPGUL010000000
VERSION     DAPGUL010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 34870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34870
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.040"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(141..1784)
                     /gene="yeeO"
                     /locus_tag="RHX21_002127"
     CDS             complement(141..1784)
                     /gene="yeeO"
                     /locus_tag="RHX21_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416491.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic metabolite efflux MATE transporter YeeO"
                     /protein_id="HDV1987306.1"
                     /translation="MLRHILTAKNLLSNPIFKFPNCLPFLSTVCCICRQFVGENLCSF
                     ADSPSLFEMWFHFLQLRSALNISSALRQVVHGTRWHAKRKSYKVLFWREITPLAVPIF
                     MENACVLLMGILSTFLVSWLGKDAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLG
                     KRDRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAGDATTEVKALALTYLEL
                     TVLSYPAAAITLIGSGALRGAGNTKIPLLINGSLNILNIIISGILIYGLFSWPGLGFV
                     GAGLGLTISRYIGAVAILWVLAIGFNPALRISLKSYFKPLNFSIIWEVMGIGIPASVE
                     SVLFTSGRLLTQMFVAGMGTSVIAGNFIAFSIAALINLPGSALGSASTIITGRRLGVG
                     QIAQAEIQLRHVFWLSTLGLTAIAWLTAPFAGVMASFYTQDPQVKHVVVILIWLNALF
                     MPIWSASWVLPAGFKGARDARYAMWVSMLSMWGCRVVVGYVLGIMLGWGVVGVWMGMF
                     ADWAVRAVLFYWRMVTGRWLWKYPRPEPQKCEKKPVVSE"
     gene            1789..1864
                     /locus_tag="RHX21_002128"
     tRNA            1789..1864
                     /locus_tag="RHX21_002128"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1822..1824,aa:Asn,seq:gtt)
     gene            complement(1902..2852)
                     /gene="cbl"
                     /locus_tag="RHX21_002129"
     CDS             complement(1902..2852)
                     /gene="cbl"
                     /locus_tag="RHX21_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator Cbl"
                     /protein_id="HDV1987307.1"
                     /translation="MNFQQLKIIREAARQDYNLTEVANMLFTSQSGVSRHIRELEDEL
                     GIEIFVRRGKRLLGMTEPGKALLVIAERILNEASNVRRLADLFTNDTSGVLTIATTHT
                     QARYSLPEVIKAFRELFPEVRLELIQGTPQEIATLLQNGEADIGIASERLSNDPQLVA
                     FPWFRWHHSLLVPHDHPLTQISPLTLESIAKWPLITYRQGITGRSRIDDAFARKGLLA
                     DIVLSAQDSDVIKTYVALGLGIGLVAEQSSGEQEEENLIRLDTRHLFDANTVWLGLKR
                     GQLQRNYVWRFLELCNAGLSVEDIKRQVMESSEEEIDYQI"
     gene            complement(2954..3871)
                     /gene="nac"
                     /locus_tag="RHX21_002130"
     CDS             complement(2954..3871)
                     /gene="nac"
                     /locus_tag="RHX21_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen assimilation transcriptional regulator
                     NAC"
                     /protein_id="HDV1987308.1"
                     /translation="MNFRRLKYFVKIVDIGSLTQAAEVLHIAQPALSQQVATLEGEFN
                     QQLLIRTKRGVTPTDAGKILYTHARAILRQCEQAQLAVHNVGQALSGQVSIGFAPGTA
                     ASSITMPLLQAVRAEFPEVVIYLHENSGAVLNEKLINHQLDMAVIYEHSPVAGVSSQA
                     LLKEDLFLVGTQDCPGQSVDVNAIAQMNLFLPSDYSAVRLRVDEAFSLRRLTAKVIGE
                     IESIATLTAAIASGMGVAVLPESAARSLCGAVNGWMSRITTPSMSLSLSLNLPARANL
                     SPQAQAVKELLMSVISSPVMEKRQWQLVS"
     gene            4198..4273
                     /locus_tag="RHX21_002131"
     tRNA            4198..4273
                     /locus_tag="RHX21_002131"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4231..4233,aa:Asn,seq:gtt)
     gene            4435..5697
                     /locus_tag="RHX21_002132"
     CDS             4435..5697
                     /locus_tag="RHX21_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDV1987309.1"
                     /translation="MSLTDAKIRTLKPSDKPFKVSDSHGLYLLVKPGGSRHWYLKYRI
                     NGKESRIALGAYPAVSLSDARQQREGVRKMLALNINPVQQRAAERGSRTPDKVFKNVA
                     LAWHKSNRKWSQNTADRLLASLNNHIFPVIGNLPVSELKPRHFIDLLKRIEEKGLLEV
                     ASRTRQHLSNIMRHAVHQGLIDTNPAANLGGVTTPPVRRHYPALPLERLPELLERIGA
                     YHQGRELTRLAVLLMLHVFIRSSELRFARWSEIDFTNRVWTIPATREPIIGVRYSGRG
                     AKMRMSHIVPLSEQSIAILKQIKDITGNNELIFPGDHNPYKPMCENTVNKALRVMGYD
                     TKKDICGHGFRAMACSALMESGLWAKDAVERQMSHQERNTVRMAYIHKAEHLEARKAM
                     MQWWSDYLEACRESYAPPYTIGKNKFIP"
     gene            complement(5891..7195)
                     /gene="ybtS"
                     /locus_tag="RHX21_002133"
     CDS             complement(5891..7195)
                     /gene="ybtS"
                     /locus_tag="RHX21_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin biosynthesis salicylate synthase
                     YbtS"
                     /protein_id="HDV1987310.1"
                     /translation="MKISEFLHLALPEEQWLPTISGVLRQFAEEECYVYERQPCWYLG
                     KGCLARLHINADGTQATFIDDAGEQQWAVDSITDCARRFMAHPQVKGRRVYGQVGFNF
                     AAHARGIAFNAGEWPLLTLTVPREELIFEKGNVTVYADSADGGRRLCEWVKEASTTTQ
                     NAPLAVDTALNGEAYKQQVARAVAEIRRGEYVKVIVSRAIPLPSRIDMPATLLYGRQA
                     NTPVRSFMFRQEGREALGFSPELVMSVTGNKVVTEPLAGTRDRMGNPEHNKAKEAELL
                     HDSKEVLEHILSVKEAIAELEAVCLPGSVVVEDLMSVRQRGSVQHLGSGVSGQLAENK
                     DAWDAFTVLFPSITASGIPKNAALNAIMQIEKTPRELYSGAILLLDDMRFDAALVLRS
                     VFQDSQRCWIQAGAGIIAQSTPERELTETREKLASIAPYLMV"
     gene            complement(7223..8503)
                     /gene="ybtX"
                     /locus_tag="RHX21_002134"
     CDS             complement(7223..8503)
                     /gene="ybtX"
                     /locus_tag="RHX21_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin-associated zinc MFS transporter
                     YbtX"
                     /protein_id="HDV1987311.1"
                     /translation="MSDVQSNVKPLTLTTGRVIFAIAGVYVTQSLVSALSMQSLPALV
                     RAAGGSLALAGATTLFMLPWALKFIWAPWIERWRLPPGSQERRSRMLILRGQVALAAI
                     LMIAAAIGWFGREGGFPDTQIVALFVLFMVAGTVASTIDIASDGFCVDQLTRAGYGWG
                     NSVQVGGSYLGMMCGGGVFLMLSAASGWPVAMLMMAMLIMALSFPLWRITEPTRTAPI
                     PHVPALGYALRRKQARLGLLLVLMLNSGMRFVLPLLAPLLLDHGLSMSALGALFSGGN
                     IAAGIAGTLAGGLLMKYTSPGRALLTAYGVQGIALLAVVMTFMMAPGHLLLPILQCLV
                     IVQSISLACALVCLYATLMSLSSPLQAGVDFTLFQCTDAAIAILAGVIGGVVAQHFGY
                     AACFLFAGVFTLLAAWVAYIRLHSARELMTSAID"
     gene            complement(8496..10298)
                     /gene="ybtQ"
                     /locus_tag="RHX21_002135"
     CDS             complement(8496..10298)
                     /gene="ybtQ"
                     /locus_tag="RHX21_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin ABC transporter
                     ATP-binding/permease protein YbtQ"
                     /protein_id="HDV1987312.1"
                     /translation="MKDNNPADNLAWRVNWRQLISSVGSQARMLRRSMLALLLAAFMQ
                     GIAFACLYPIIDALLRGDAPQLLNWAMAFSVAAIVTLVLRWYGLGFEYRGHLAQATHE
                     LRLRLGEQLRRVPLEKLQRGRAGEMNALLLGSVDENLNYVIAIANILLLTIVTPLTAS
                     LATLWIDWRLGLVMLLIFPLLVPFYYWRRPAMRRQMQTLGEAHQRLSGDIVEFAQGMM
                     VLRTCGSDADKSRALLAHFNALENLQTRTHRQGAGATMLIASVVELGLQVVVLSGIVW
                     VVTGTLNLAFLIAAVAMIMRFAEPMAMFISYTSVVELIASALQRIERFMAIAPLPVAE
                     QSEMPERYDIRFDNVSYRYEEGDGHALNHVSLTFPAASMSALVGASGAGKTTVTKLLM
                     RYADPQQGQISIGGVDIRRLTPEQLNSLISVVFQDVWLFDDTLLANIRIARPQATRQE
                     VEEAARAAQCLEFISRLPQGWLTPMGEMGGQLSGGERQRISIARALLKNAPVVILDEP
                     TAALDIESELAVQKAIDNLVHNRTVIIIAHRLSTIAGAGNILVMEEGQVVEQGTHAQL
                     LSHHGRYQALWQAQMAARVWRDDGVSASGEWVHE"
     gene            complement(10285..11997)
                     /gene="ybtP"
                     /locus_tag="RHX21_002136"
     CDS             complement(10285..11997)
                     /gene="ybtP"
                     /locus_tag="RHX21_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin ABC transporter
                     ATP-binding/permease protein YbtP"
                     /protein_id="HDV1987313.1"
                     /translation="MALAGLAALTSLGALLFLAWSLRDIRATPDAIPAWPLGGVIGCV
                     VLTFVLRLQAFNTSHYAAFHLENILRSRLARKALQLPPGVLQQMGSGSVAKVMLDDVK
                     SLHIFVADSTPLYARAIIMPLATIVILFWLDWRLAIATLGVLAFGSVVLVLARQRSED
                     MAQRYHKAREQVSAAVIEFVQAMPVVRTFDSGSTSFLRYQRALEEWVDVLKTWYRKAG
                     FSARFSFSILNPLPTLFVLIWSGYGLLHYGSFDFIAWVAVLLLGSGMAEAVMPMMMLN
                     NLVAQTRLSIQRIYQVLAMPELSLPQSDQQPQEASITFEQVSFHYPQARTGAALQEVS
                     FHVPAGQIVALVGPSGAGKSTVARLLLRYADPDKGHIRIGGVDLRDMQTDTLMKQLSF
                     VSQDNFLFADTIANNIRLGAPDTPLEAVIAAARVAQAHDFISALPEGYNTRVGERGVF
                     LSGGQRQRITIARALLQDRPILVLDEATAFADPENEAALIKALAAAMRGRTVIMVAHR
                     LSMVTQADVILLFSDGQLREMGNHTQLLAQGGLYQRLWQHYQQAQHWVPGGTQEEVVE
                     NERQ"
     gene            12254..13213
                     /gene="ybtA"
                     /locus_tag="RHX21_002137"
     CDS             12254..13213
                     /gene="ybtA"
                     /locus_tag="RHX21_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin transcriptional regulator YbtA"
                     /protein_id="HDV1987314.1"
                     /translation="MTESPQTQSEISIHQLVVGKPANDGNIPAQCELLRCSLQEGMDI
                     LLWRGHFARPETLQLHDDLGRINFSCILEGTSRFAIQGLRRHTDWELARNRHYITHTP
                     DCRGSASYCGRFESITLSFSPATLALWVPDISADIKNKIDSHCCCQQQRCNAETHLTA
                     QALRHALMRMHGGFSHEQKPSTLWLQGQSLVMLSLVLDEHREDASCLSCHFNPMERQK
                     LLRAKDLLLADLTQAPGVAELARESGLSVLKIKRGFRVLFNNSVYGLFQAERMQEARR
                     RLANGNTSVMTVAADLGYANASHFSAAFQKQFGVTPSTFKRVM"
     gene            13404..19511
                     /gene="irp2"
                     /locus_tag="RHX21_002138"
     CDS             13404..19511
                     /gene="irp2"
                     /locus_tag="RHX21_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin non-ribosomal peptide synthetase
                     HMWP2"
                     /protein_id="HDV1987315.1"
                     /translation="MISGAPSQDSLLPDNRHAADYQQLRERLIQELNLTPQQLHEESN
                     LIQAGLDSIRLMRWLHWFRKNGYRLTLRELYAAPTLAAWNQLMLSRSPENAEEETPPD
                     ESSWPNMTESTPFPLTPVQHAYLTGRMPGQTLGGVGCHLYQEFEGHCLTASQLEQAIT
                     TLLQRHPMLHIAFRPDGQQVWLPQPYWNGVTVHDLRHNDAESRQAYLDALRQRLSHRL
                     LRVEIGETFDFQLTLLPDNRHRLHVNIDLLIMDASSFTLFFDELNALLAGESLPAIDT
                     RYDFRSYLLHQQKINQPLRDDARAYWLAKASTLPPAPVLPLACEPATLREVRNTRRRM
                     IVPATRWHAFSNRAGEYGVTPTMALATCFSAVLARWGGLTRLLLNITLFDRQPLHPAV
                     GAMLADFTNILLLDTACDGDTVSNLARKNQLTFTEDWEHRHWSGVELLRELKRQQRYP
                     HGAPVVFTSNLGRSLYSSRAESPLGEPEWGISQTPQVWIDHLAFEHHGEVWLQWDSND
                     ALFPPALVETLFDAYCQLINQLCDDESAWQKPFADMMPASQRAIRERVNATGAPIPEG
                     LLHEGIFRIALQQPQALAVTDMRYQWNYHELTDYARRCAGRLIECGVQPGDNVAITMS
                     KGAGQLVAVLAVLLAGAVYVPVSLDQPAARREKIYADASVRLVLICQHDASAGSDDIP
                     VLAWQQAIEAEPIANPVVRAPTQPAYIIYTSGSTGTPKGVVISHRGALNTCCDINTRY
                     QVGPHDRVLALSALHFDLSVYDIFGVLRAGGALVMVMENQRRDPHAWCELIQRHQVTL
                     WNSVPALFDMLLTWCEGFADATPENLRAVMLSGDWIGLDLPARYRAFRPQGQFIAMGG
                     ATEASIWSNACEIHDVPAHWRSIPYGFPLTNQRYRVVDEQGRDCPDWVPGELWIGGIG
                     VAEGYFNDPLRSEQQFLTLPDERWYRTGDLGCYWPDGTIEFLGRRDKQVKVGGYRIEL
                     GEIESALSQLAGVKQATVLAIGEKEKTLAAYVVPQGEAFCITDHRNPALPQAWHTLAG
                     TLPCCAISPEISAEQVADFLQHRLLKLKPGHTAGADPLPLMNSLAIQPRWQAVVERWL
                     AFLVTQRRLKPAAEGYQVCAGEEREDEHPHFSGHDLTLSQILRGARNELSLLNDAQWS
                     PESLAFNHPASAPYIQELATICQQLAQRLQRPIRLLEVGTRTGRAAESLLAQLNAGQI
                     EYVGLEQSQEMLLSARQRLAPWPGARLSLWNADTLATHAHSADIIWLNNALHRLLPED
                     PGLLATLQQLAVPGALLYVMEFRQLTPSALLSTLLLTNGQPEALLHNSADWAALFSAA
                     AFNCQHGDEVAGLQRFLVQCPDRQVRRDPRQLQAALAGRLPGWMVPQRIVFLDALPLT
                     ANGKIDYQALKRRHTPEAENPAEADLPQGDIEKQVAALWQQLLSTGNVTRETDFFQQG
                     GDSLLATRLTGQLHQAGYEAQLSDLFNHPRLADFAATLRKTDVPVEQPFVHSPEDRYQ
                     PFALTDVQQAYLVGRQPGFALGGVGSHFFVEFEIADLDLTRLETVWNRLIARHDMLRA
                     IVRDGQQQVLEQTPPWVIPAHTLHTPEEALRVREKLAHQVLNPEVWPVFDLQVGYVDG
                     MPARLWLCLDNLLLDGLSMQILLAELEHGYRYPQQLLPPLPVTFRDYLQQPSLQSPNP
                     DSLAWWQAQLDDIPPAPALPLRCLPQEVETPRFARLNGALDSTRWHRLKKRAADAHLT
                     PSAVLLSVWSTVLSAWSAQPEFTLNLTLFDRRPLHPQINQILGDFTSLMLLSWHPGES
                     WLHSAQSLQQRLSQNLNHRDVSAIRVMRQLAQQQNVPAVPMPVVFTSALGFEQDNFLA
                     RRNLLKPVWGISQTPQVWFDHQIYESEGELRFNWDFVAALFPAGQVERQFEQYCALLN
                     RMAEDESGWQLPLAALVPPVKHAGQCAERSPRVCPEQSQPHIAADESTVSLICDAFRE
                     VVGESVTPAENFFEAGATSLNLVQLHVLLQRHEFSTLTLLDLFTHPSPVALADYLAGV
                     TTVEKTKRPRPVRRRQRRI"
     gene            19599..29090
                     /gene="irp1"
                     /locus_tag="RHX21_002139"
     CDS             19599..29090
                     /gene="irp1"
                     /locus_tag="RHX21_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin polyketide synthase HMWP1"
                     /protein_id="HDV1987316.1"
                     /translation="MDNLRFSSAPTADSIDASIAQHYPDCEPVAVIGYACHFPESPDG
                     ETFWQNLLEGRECSRRFTREELLAVGLDAAIIDDPHYVNIGTVLDNADCFDATLFGYS
                     RQEAESMDPQQRLFLQAVWHAMEHAGYAPGAVPHKTGVFASSRMSTYPGREALNVTEV
                     AQVKGLQSLMGNDKDYIATRAAYKLNLHGPALSVQTACSSSLVAVHLACESLRAGESD
                     MAVAGGVALSFPQQAGYRYQPGMIFSPDGHCRPFDASAEGTWAGNGLGCVVLRRLRDA
                     LLSGDPIISVILSSAVNNDGNRKVGYTAPSVAGQQAVIEEALMLAAIDDRQVGYIETH
                     GTGTPLGDAIEIEALRNVYAPRPQDQRCALGSVKSNMGHLDTAAGIAGLLKTVLAVSR
                     GQIPPLLNFHTPNPALKLEESPFTIPVSAQAWQDEMRYAGVSSFGIGGTNCHMIVASL
                     PDALNARLPNTDSGRKSTALLLSAASDSALRRLATDYAGALRENADASSLAFTALHAR
                     RLDLPFRLAAPLNRETAEALSAWAGEKSGALVYSGHGASGKQVWLFTGQGSHWRTMGQ
                     TMYQHSTAFADTLDRCFSACSEMLTPSLREAMFNPDSAQLDNMAWAQPAIVAFEIAMA
                     AHWRAEGLKPDFAIGHSVGEFAAAVVCGHYTIEQVMPLVCRRGALMQQCASGAMVAVF
                     ADEDTLMPLARQFELDLAANNGTQHTVFSGPEARLAVFCATLSQHDINYRRLSVTGAA
                     HSALLEPILDRFQDACAGLHAEPGQIPIISTLTADVIDESTLNQADYWRRHMRQPVRF
                     IQSIQVAHQLGARVFLEMGPDAQLVACGQREYRDNAYWIASARRNKEASDVLNQALLQ
                     LYAAGVALPWADLLAGDGQRIAAPCYPFDTERYWKERVSPACEPADAALSAGLEVASR
                     AATALDLPRLEALKQCATRLHAIYVDQLVQRCTGDAIENGVDAMTIMRRGRLLPRYQQ
                     LLQRLLNNCVVDGDYRCTDGRYVRARPIEHQQRESLLTELAGYCEGFQAIPDTIARAG
                     DRLYEMMSGAEEPVAIIFPQSASDGVEVLYQEFSFGRYFNQIAAGVLRGIVQTRQPRQ
                     PLRILEVGGGTGGTTAWLLPELNGVPALEYHFTDISALFTRRAQQKFADYDFVKYSEL
                     DLEKEAQSQGFQAQSYDLIVAANVIHATRHIGRTLDNLRPLLKPGGRLLMREITQPMR
                     LFDFVFGPLVLPLQDLDAREGELFLTTAQWQQQCRHAGFSKVAWLPQDGSPTAGMSEH
                     IILATLPGQAVSAVTFTAPSEPVLGQALTDNGDYLADWSDCAGQPERFNARWQEAWRL
                     LSQRHGDALPVEPPPVAAPEWLGKVRLSWQNEAFSRGQMRVEARHPAGEWLPLSPAAP
                     LPAPQTHYQWRWTPLNVASIDQPLTFSFSAGTLARSDELAQYGIIHDPHASSRLMIVE
                     ESEDTLALAEKVIAALTASAAGLIVVTRRAWRVEENEALSASHHALWALLRVAANEQP
                     ERLLAAIDLAENTPWETLHQGLSAVSLSQRWLAARGDTLWLPSLAPNTGCAAELPANV
                     FTGDSRWHLVTGAFGGLGRLAVNWLREKGARRIALLAPRVDESWLRDVEGGQTRVCRC
                     DVGDAGQLATVLDDLAANGGIAGAIHAAGVLADAPLQELDDHQLAAVFAVKAQAASQL
                     LQTLRNHDGRYLILYSSAAATLGAPGQSAHALACGYLDGLAQQFSTLDAPKTLSVAWG
                     AWGESGRAATPEMLATLASRGMGALSDAEGCWHLEQAVMRGAPWRLAMRVFTDKMPPL
                     QQALFNISATEKAATPVIPPADDNAFNGSLSDETAVMAWLKKRIAVQLRLSDPASLHP
                     NQDLLQLGMDSLLFLELSSDIQHYLGVRINAERAWQDLSPHGLTQLICSKPEATPAAS
                     QPEVLRHDADERYAPFPLTPIQHAYWLGRTHLIGYGGVACHVLFEWDKRHDEFNLAIL
                     EKAWNQLIARHDMLRMVVDADGQQRILATTPEYHIPRDDLRALSPEEQRIALEKRRHE
                     LSYRVLPADQWPLFELVVSEIDDCHYRLHMNLDLLQFDVQSFKVMMDDLAQVWRGETL
                     APLAITFRDYVMAEQARRQTSAWHDAWDYWQEKLPQLPLAPELPVVETPPETPHFTTF
                     KSTIGKTEWQAVKQRWQQQGVTPSAALLTLFAATLERWSRTTTFTLNLTFFNRQPIHP
                     QINQLIGDFTSVTLVDFNFSAPVTLQEQMQQTQQRLWQNMAHSEMNGVEVIRELGRLR
                     GSQRQPLMPVVFTSMLGMTLEGMTIDQAMSHLFGEPCYVFTQTPQVWLDHQVMESDGE
                     LMFSWYCMDNVLEPGAAEAMFNDYCAILQAVIAAPESLKTLASGIAGHIPRRRWPLNA
                     QADYDLRDIEQATLEYPGIRQARAEITEQGALTLDIVMADDPSPSAAMPDEHELTQLA
                     LPLPEQAQLDELEATWRWLEARALQGIAATLNRHGLFTTPEIAHRFSAIVQALSAQAS
                     HQRLLRQWLQCLTEREWLIREGESWRCRIPLSEIPEPQEACPQSQWSQALAQYLETCI
                     ARHDALFSGRCSPLELLFNEQHRVTDALYRDNPASACLNRYTAQIAALCSAERILEIG
                     AGTAATTAPVLKATRNTRQSYHFTDVSAQFLNDARARFHDESQVSYALFDINQPLDFT
                     AHPEAGYDLIVAVNVLHDASHVVQTLRRLKLLLKAGGRLLIVEATERNSVFQLASVGF
                     IEGLSGYRDFRRRDEKPMLTRSAWQEVLVQAGFANELAWPAQESSPLRQHLLVARSPG
                     VNRPDKKAVSRYLQQRFGTGLPILQIRQREALFTPLHAPSDTPTEPAKPTPVAGGNPA
                     LERQVAELWQSLLSRPVARHHDFFELGGDSLMATRMVAQLNRRGIARANLQDLFSHST
                     LSDFCAHLQAATSGEDNPIPLCQGDGEETLFVFHASDGDISAWLPLASALNRRVFGLK
                     AKSPQRFATLDQMIDEYVGCIRRQQPHGPYVLAGWSYGAFLAAGAAQRLYAKGEQVRM
                     VLIDPVCRQDFCCENRAALLRLLAEGQTPLALPEHFDQQTPDSQLADFISLAKTAGMV
                     SQNLTLQAAETWLDNIAHLLRLLTEHTPGESVPVPCLMVYAAGRPARWTPAETEWQGW
                     INNADDAVIEASHWQIMMEAPHVQACAQHITRWLCATSTQPENTL"
     gene            29087..30187
                     /gene="ybtU"
                     /locus_tag="RHX21_002140"
     CDS             29087..30187
                     /gene="ybtU"
                     /locus_tag="RHX21_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin biosynthesis oxidoreductase YbtU"
                     /protein_id="HDV1987317.1"
                     /translation="MMPSASPKQRVLIVGAKFGEMYLNAFMQPPEGLELVGLLAQGSA
                     RSRELAHAFGIPLYTSPEQITRMPDIACIVVRSTVAGGTGTQLARHFLTRGVHVIQEH
                     PLHPDDISSLQTLAQEQGCCYWVNTFYPHTRAGRTWLRDAQQLHRCLAKTPPVVHATT
                     SRQLLNSTLDLLLLALGVDAAAVECDVVGSFSDFHCLRLFWPEGEACLLLQRYLDPDD
                     PDMHSLIMHRLLLGWPEGHLSLEASYGPVIWSSSLFVADHQENAHSLYRRPEILRDLL
                     GLTRSAAPLSWRDCCETVGPEGVSWLLHQLRSHLAGEHPPAACQSVHQIALSRLWQQI
                     LRKTGNAEIRRLTPPHHDRLAGFYNDDDKEAL"
     gene            30184..30987
                     /gene="ybtT"
                     /locus_tag="RHX21_002141"
     CDS             30184..30987
                     /gene="ybtT"
                     /locus_tag="RHX21_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002212799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin biosynthesis thioesterase YbtT"
                     /protein_id="HDV1987318.1"
                     /translation="MTQSAMCIPLWPARNGNTAHLVMCPFAGGSSSAFRHWQAEQLAD
                     CALSLVTWPGRDRLRHLEPLRSITQLAALLANELEASVSPDTPLLLAGHSMGAQVAFE
                     TCRLLEQRGLAPQGLIISGCHAPHLHSERQLSHRDDADFIAELIDIGGCSPELQENQE
                     LMSLFLPLLRADFYATESYHYDSPDVCPPLRTPALLLCGSHDREASWQQVDAWRQWLS
                     HVTGPVVIDGNHFYPIQQARSFFTQIVRHFPHAFSAMTALQKQPSTSER"
     gene            30991..32568
                     /gene="ybtE"
                     /locus_tag="RHX21_002142"
     CDS             30991..32568
                     /gene="ybtE"
                     /locus_tag="RHX21_002142"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="yersiniabactin biosynthesis salycil-AMP ligase
                     YbtE"
                     /protein_id="HDV1987319.1"
                     /translation="MNSSFKSLIEQYPLPIAEQLRHWAARYASRIAVVDAKGSLTYSA
                     LDAQVDELAAGLSSLGLRSGEHVIVQLPNDNAFVTLLFSLLRLGVIPVLAMPSQRALD
                     IDALIELAQPVAYVIQGENHAELARQMAHKHACLRHVLVAGETVSDDFTPLFSLHGER
                     QAWPQPDVSATALLLLSGGTTGTPKLIPRRHADYSYNFSASAELCGISQQSVYLAVLP
                     VAHNFPLACPGILGTLACGGKVVLTDSASCDEVMPLIAQERVTHVALVPALAQLWVQA
                     REWEDSDLSSLRVIQAGGARLDPTLAEQVIATFDCTLQQVFGMAEGLLCFTRLDDPHA
                     TILHSQGRPLSPLDEIRIVDQDENDVAPGETGQLLTRGPYTISGYYRAPAHNAQAFTA
                     QGFYRTGDNVRLDEVGNLHVEGRIKEQINRAGEKIAAAEVESALLRLAEVQDCAVVAA
                     PDTLLGERICAFIIAQQVPTDYQQLRQQLTRMGLSAWKIPDQIEFLDHWPLTAVGKID
                     KKRLTALAVDHYRHSAQ"
     gene            32699..34720
                     /gene="fyuA"
                     /locus_tag="RHX21_002143"
     CDS             32699..34720
                     /gene="fyuA"
                     /locus_tag="RHX21_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore yersiniabactin receptor FyuA"
                     /protein_id="HDV1987320.1"
                     /translation="MKMTRLYPLALGGLLLPAIANAQTSQQDESTLVVTASKQSSRSA
                     SANNVSSTVVSAPELSDAGVTASDKLPRVLPGLNIENSGNMLFSTISLRGVSSAQDFY
                     NPAVTLYVDGVPQLSTNTIQALTDVQSVELLRGPQGTLYGKSAQGGIINIVTQQPDST
                     PRGYIEGGVSSRDSYRSKFNLSGPIQDGLLYGSVTLLRQVDDGDMINPATGSDDLGGT
                     RASIGNVKLRLAPDDQPWEMGFAASRECTRATQDAYVGWNDIKGRKLSISDGSPDPYM
                     RRCTDSQTLSGKYTTDDWVFNLISAWQQQHYSRTFPSGSLIVNMPQRWNQDVQELRAA
                     TLGDARTVDMVFGLYRQNTREKLNSAYDMPTMPYLSSTGYTTAETLAAYSDLTWHLTD
                     RFDIGGGVRFSHDKSSTQYHGSMLGNPFGDQGKSNDDQVLGQLSAGYMLTDDWRVYTR
                     VAQGYKPSGYNIVPTAGLDAKPFVAEKSINYELGTRYETADVTLQAATFYTHTKDMQL
                     YSGPVGMQTLSNAGKADATGVELEAKWRFAPGWSWDINGNVIRSEFTNDSELYHGNRV
                     PFVPRYGAGSSVNGVIDTRYGALMPRLAVNLVGPHYFDGDNQLRQGTYATLDSSLGWQ
                     ATERMNISVYVDNLFDRRYRTYGYMNGSSAVAQVNMGRTVGINTRIDFF"
BASE COUNT         7729 a        10437 c         9458 g         7246 t
ORIGIN      
        1 gattaacagt ccgccgttct accgactgaa ctacagagga atcgtgagaa cgaggcgaat
       61 attagcgatg cccacccaca atgtcaaagc ctgtttttta aatttgaaat cgtttgctga
      121 aataatctgc attttgtcgt ttattccgac acaactggct ttttttcaca cttttgcggc
      181 tcgggtcgag ggtatttcca tagccaacgt ccagtaacca ttcgccagta aaacagcacg
      241 gcccgcacag cccagtcggc aaacattccc atccagacac caaccacacc ccagccaagc
      301 atgattccca gcacataacc gactacaacc cgacaacccc acatgctcaa catcgaaacc
      361 cacatggcgt aacgggcatc acgagcacct ttaaatccag cgggtagcac ccatgaggcg
      421 gaccaaatag gcataaataa agcatttagc caaatcagaa tcacaacgac atgtttaacc
      481 tgtggatcct gggtgtaaaa cgatgccata accccggcaa agggagccgt tagccaggcg
      541 atggccgtta atccaagagt ggaaagccag aacacatgcc gcaactgaat ctctgcttgc
      601 gctatctgcc ctacccccaa ccttcggcct gtaatgatcg tagaagcaga gccgagcgca
      661 cttccgggta agttgataag agccgcaatt gaaaacgcga taaaatttcc ggcaataaca
      721 ctggtcccca tcccggcaac gaacatttgg gttaataacc gaccactggt aaataacact
      781 gattcgacac tcgcgggaat accaatcccc atgacttccc agataatgct aaaattcagc
      841 ggtttaaaat agctctttaa cgaaatcctt agcgcaggat taaaaccaat cgccagcacc
      901 cacaaaattg caactgcgcc aatataacga gaaatggtta aacccagccc tgccccgaca
      961 aatcccagtc ccggccagga gaaaaggccg taaatcaata tgccgctaat aataatatta
     1021 agaatattca ggctaccgtt aatcaatagc ggtattttcg tattccctgc accacgaagt
     1081 gccccgctac caataagagt gatggcagct gctggataac tgagtaccgt cagctccaga
     1141 taagtcaacg ccagtgcttt aacttctgtc gtggcatcac ccgcgacgaa atcaataatt
     1201 tgttcgccaa aatgatgaat aagcgttgcc aacagtacgg caaacaacgt catgatcacc
     1261 aatgactgcc gcgtcgccac cctcgctcgt cgtcgatccc gcttaccgag actaaatgcc
     1321 acaacgacag tagtaccaag atcgatagca gcaaaaaaag ccataatgac catattgaag
     1381 ctgtccgcca atcccacgcc ggccatcgca tcttttccca gccagctgac cagaaaagtg
     1441 ctcagaatcc ccatcaacag gacacaggca ttctccatga agataggaac agcaagcggg
     1501 gttatctcgc gccagaacaa cactttgtag ctcttgcgtt tagcgtgcca gcgagtgccg
     1561 tgaacaacct ggcgtaaagc agaggagata ttcaaagccg accttaattg cagaaagtga
     1621 aaccacattt caaataatga gggagaatca gcaaagctgc aaagattttc gccaacaaat
     1681 tgtctgcaaa tgcaacaaac tgttgataga aacggcaaac agttggggaa tttaaaaatc
     1741 gggtttgaca aaagattttt cgccgttaag atgtgcctca acaacgattc ctctgtagtt
     1801 cagtcggtag aacggcggac tgttaatccg tatgtcactg gttcgagtcc agtcagagga
     1861 gccaaattcc tgaaaagccc gcttttatag cgggattttt gctatatctg ataatcaatt
     1921 tcctcttcac tgctttccat cacctgccgc ttgatatcct caactgacag tcctgcatta
     1981 caaagttcca gaaagcgcca gacatagtta cgctgaagtt gtcctcgctt cagtcccaac
     2041 cagacagtat tagcatcaaa aagatgccgc gtatccaggc ggattaaatt ctcttcctct
     2101 tgttcgccac tggattgctc ggcaactaat ccgatcccaa gcccaagagc aacataggtt
     2161 ttaatgacat cagaatcctg cgcacttaat acaatatctg ccagcaaacc tttgcgggca
     2221 aatgcgtcat caatacgtga gcgccccgta atcccctgtc ggtaagtgat taacggccac
     2281 ttcgctattg attccagcgt caatggtgaa atttgcgtca agggatgatc gtgtggaaca
     2341 agcaaactat ggtgccaacg aaaccacggg aaggcgacga gctgcgggtc attactcaaa
     2401 cgctcgctgg cgataccaat atcagcttcg ccattttgca acaatgtcgc aatttcctgt
     2461 ggcgtcccct ggattagctc gagccgaacc tccgggaaaa gttcgcgaaa agctttaatg
     2521 acctctggca agctataacg tgcctgagta tgcgtcgttg caatagtgag aacgccagac
     2581 gtatcgttgg taaacaggtc tgcaagccga cgaacattac tggcttcatt cagaatacgt
     2641 tctgcaatga ccagtaatgc tttgcccggt tcagtcatgc ccagcagtcg cttacctcgt
     2701 cgaacaaata tttcgatgcc aagttcatcc tccagttccc gaatatgacg gctgacgcct
     2761 gactgtgagg taaaaagcat attcgcaacc tctgtcaggt tgtaatcctg acgtgcagcc
     2821 tcgcggatta tctttagttg ttggaaattc acggtaaact ccgggcagtt cagatttccc
     2881 gttattgtta aagtctaatg cccggcataa caaataataa aaacccgcat cttattccat
     2941 cccgatataa cacttagctc accaattgcc actgcctttt ttccatcact ggagaactaa
     3001 tcactgacat taacaactct ttcactgcct gtgcctgtgg cgataagttc gctctggcgg
     3061 gtaaatttaa tgacaaagag agactcatgg aaggagtggt aatgcgtgac atccacccgt
     3121 ttactgcgcc acataacgaa cgcgcggccg attcgggtaa tactgcaacg cccatgccgc
     3181 tggcaatcgc tgcggtaagc gtggcaatag actcaatttc accaatgact tttgccgtga
     3241 gtcgccgtag ggaaaaagcc tcatcaacac gaagtctaac agcactgtaa tcactgggaa
     3301 gaaagaggtt catttgcgca atagcattaa catcaacgct ttgccccgga caatcttgag
     3361 tccctaccag gaaaagatct tctttcagta aagcctgact ggatacacca gccacagggg
     3421 aatgctcata aatcaccgcc atatcgagtt ggtgatttat cagtttttcg ttaagcactg
     3481 caccgctatt ttcatgaaga tagataacga cctccgggaa ttcagcgcga accgcctgta
     3541 ataagggcat ggtgatggat gacgcagcgg ttcctggcgc aaagccaatc gagacttgcc
     3601 ccgataatgc ctgaccaacg ttatgcaccg ccagttgggc ctgctcacac tgacgtaaaa
     3661 tggcccgcgc atgggtatag agaatttttc cggcgtcagt tggcgtaacg ccccgttttg
     3721 tgcgaatcaa aagttgttga ttaaactcac cttccagtgt ggcaacctgc tggctgagcg
     3781 ctggttgtgc gatatgcaat acttcagcag cctgggtcag gctaccaata tctacaattt
     3841 ttacgaagta tttcaggcgt ctgaagttca tgttgcctcc ggtttttaag agtcggccca
     3901 agtgccgcca ttacttacaa ccagaatgca agatgcttgc cagttctatt ttggcgttga
     3961 tgcgcaagct aaccaactgt caaataagag attatgatag attcgtcatt ggctcttttt
     4021 atctgcagtc gcattcacct gccctataaa aggagggtat gcaccacgat ggttcattac
     4081 ccaataagat tgaaagctca ccactttgtt gaaattggca gcaaacaaac aaaaaaatgc
     4141 atttcaccct ttgacatcac catgcactgc cattaatatg cgccccgttc acacgattcc
     4201 tctgtagttc agtcggtaga acggcggact gttaatccgt atgtcactgg ttcgagtcca
     4261 gtcagaggag ccaatttgct gttttcatgc atccttgcga atcattatat gatgttggtt
     4321 caacaggtta gcgtgaaaac tcttcccggt gcattttgat tttaccctcc gcatcgggaa
     4381 aaattggtgg tcaaatctgg ggtcaggtta gttcgataat ggagcgaccc ccatatgtcc
     4441 cttaccgacg cgaaaatccg cactctcaaa ccttctgata aaccctttaa agtctccgat
     4501 tcccacggtc tgtatctgct ggtcaagccg ggtggctcac gtcactggta tctcaagtac
     4561 cgtattaacg gtaaagaatc gcgcattgcg ctgggtgcct atcctgccgt ctccctctct
     4621 gatgcgcgac agcagcgtga aggtgtccgt aaaatgctgg cgctgaatat caacccggta
     4681 cagcagcggg ctgctgaacg tggctcacga acaccggata aagtttttaa aaacgtggcg
     4741 ctggcgtggc ataaaagtaa ccggaaatgg tcgcagaaca ccgctgaccg tctgcttgcc
     4801 agcctgaaca atcacatctt tccggtcatt ggcaacctgc ctgtatcaga acttaaaccc
     4861 cgtcatttca ttgacctgct gaaaaggatc gaggaaaaag gtctgctgga agttgcgtcc
     4921 cgcacgcggc agcacctgag taacataatg cgccatgcgg ttcatcaggg gttaatcgat
     4981 acgaacccgg cagcaaatct tggcggcgtg accacacctc ctgtcagacg gcactatcct
     5041 gccctgccac tggagcggct gcctgaactg cttgaacgta ttggggcata tcatcagggt
     5101 cgtgaactga cgcggttggc cgtcctgctg atgctgcatg tgttcattcg ctccagtgaa
     5161 ctgcgtttcg cccgctggtc agagattgat ttcacaaacc gagtctggac gatacccgcg
     5221 acgcgagaac ccattattgg agtgcgttat tccggccgcg gggccaaaat gcgaatgtcg
     5281 catatcgtcc ccctctcaga acagtccatc gccattctga aacagattaa ggatatcacc
     5341 ggtaataatg aactgatctt ccccggcgac cataacccgt ataagccaat gtgtgaaaac
     5401 acggtcaata aggcactgcg ggtgatgggc tacgacacga aaaaggatat ctgcggtcac
     5461 ggcttccggg caatggcatg cagtgcgctg atggaatcgg gtttatgggc aaaggacgca
     5521 gtagaacgcc agatgagtca tcaggagcgc aataccgtgc gcatggctta tattcataag
     5581 gcagagcacc tagaagcccg caaagcgatg atgcagtggt ggtcggatta tctggaagca
     5641 tgccgagaat cttatgcacc gccttataca attggtaaaa ataagtttat cccatagtat
     5701 actaacgaat cccacactct ggcaaattac caccacctct acaggaggtg gttctatata
     5761 gacttttatc aacttcatga cgaaaaacac ctattttatc caaaaagaag acaatagagt
     5821 cacagaggaa tcaaagagcg actcaattgt ctttggacag tctggttgtg aggttagaaa
     5881 acagttactc ctacaccatt aaatagggcg caatgctcgc taatttctcc cgggtttccg
     5941 tcagttcgcg ttccggtgta gattgcgcga tgattcccgc ccccgcttgt atccagcagc
     6001 gctggctgtc ctgaaatacg gaacgcagaa ctagcgccgc atcgaagcgc atatcgtcca
     6061 gcagcagaat tgcgccggaa tagagctctc gcggcgtctt ctcaatttgc ataatcgcgt
     6121 tcagggcagc gtttttaggg atacctgagg cggtaatcga cggaaacagc acggtaaacg
     6181 catcccaggc atccttgttt tccgcaagct gaccgctcac gccggacccc agatgctgaa
     6241 cgctgccgcg ctggcgaacc gacattaaat cttcaaccac cacgctgccc ggcaggcaaa
     6301 cggcctccag ttcagcaatc gcttctttga cagaaaggat atgctcaagc acctctttac
     6361 tgtcgtgcag cagttctgcc tctttcgcct tattatgctc cgggtttccc atgcgatcgc
     6421 gggtgcccgc aagcggttca gtgaccactt tattgcccgt cactgacatc accagttccg
     6481 ggctaaagcc cagcgcttcg cgtccttcct gacggaacat aaacgagcgc acaggtgtat
     6541 ttgcctgccg cccgtataac agcgtggcgg gcatatcaat ccgcgatggc aggggaatag
     6601 cgcgcgagac aatcactttg acatactcgc cacggcggat ctccgcaacg gcgcgtgcaa
     6661 cctgttgttt atacgcctcg ccattgaggg cggtatccac cgccagtggt gcgttctgcg
     6721 tcgttgtact ggcctctttt acccactcac acaaacgtcg gcccccgtcg gcggagtccg
     6781 cataaacggt gacatttccc ttttcaaaaa taagttcttc acggggaacg gttaacgtca
     6841 gcagcggcca ctccccggcg ttaaaggcaa tcccccgcgc atgcgccgca aagttgaacc
     6901 caacctgtcc ataaacccga cgtcctttca cctgaggatg tgccataaaa cgacgcgcgc
     6961 agtcggtaat ggaatccacc gcccattgtt gctccccggc atcatcaata aatgtcgcct
     7021 gcgttccgtc ggcattaatg tgcaaccgtg ccaggcaccc tttgcctaaa taccaacagg
     7081 gttgacgctc atagacataa cactcttctt ctgcgaactg gcgtaaaacg ccagaaatcg
     7141 tcggcagcca ttgttcctct ggtaacgcca ggtgtaaaaa ttcactgatt ttcatccctt
     7201 acctctctgt gttattcccg gatcaatcaa ttgcgcttgt catcagttct cttgccgaat
     7261 gcagccggat ataagcaacc cacgccgcca gcaacgtgaa taccccggca aacaggaagc
     7321 aggccgcata gccaaaatgt tgagcaacaa cgccgccgat aacaccagcc aggatggcga
     7381 ttgccgcgtc agtacattga aagagggtga agtcgacacc ggcctgcaaa ggcgatgaaa
     7441 gcgacatcag cgtggcgtaa agacagacca gcgcgcaggc cagcgaaatg gactggacaa
     7501 taaccagaca ctggagaatc ggcagcaaca gatgacccgg cgccatcatg aacgtcatca
     7561 ccaccgccag cagcgcgatc ccctggacgc cataagccgt caacagcgct ctgccgggtg
     7621 aggtgtattt catcagtaat ccgccggcca gcgttcctgc tatgcccgct gcaatattgc
     7681 cgccgctgaa cagcgcgccc aacgcagaca tgctcaaccc atgatccaac aacagcggcg
     7741 ccagaagagg cagcacaaac cgcatacctg aattcagcat taataccagc agtaagccca
     7801 ggcgcgcctg cttcctcctt agcgcataac ctaacgccgg aacatgcggg ataggcgctg
     7861 ttcgcgtcgg ctccgtaatg cgccacagcg ggaatgacag cgccataatc agcatcgcca
     7921 tcatcagcat ggcgacaggc cagccggatg ctgccgacaa cattaggaac accccgccgc
     7981 cgcacatcat tcccagatag ctgccgccga cctgcacgct gtttccccag ccgtaacccg
     8041 cgcgagtcag ttgatcgacg caaaagccgt cgctggcgat atcaatggtg gaagcgaccg
     8101 tgcctgccac cataaacaga acaaataacg cgacgatttg cgtatcggga aatcctcctt
     8161 ctcgcccaaa ccagccaatc gctgcggcaa tcatcaggat cgccgctagc gcgacctgac
     8221 cacgcaggat taacatccgc gaacggcgtt cctggctacc gggcggaagc cgccagcgtt
     8281 cgatccacgg cgcccaaata aacttcagcg cccagggcag catgaacagg gttgtcgcac
     8341 cggcaagcgc cagcgatccg ccagcagcgc gcaccagcgc gggtaaggac tgcatagaca
     8401 gcgccgatac cagactctgc gtcacataga cgccggcaat agcaaaaatc acccgcccgg
     8461 tcgtcaacgt cagcggtttc acattcgact gaacatcact catgcaccca ctctccagac
     8521 gcggaaaccc cgtcgtcgcg ccacacgcgc gcggccattt gcgcctgcca cagcgcctga
     8581 taacgtccat gatgtgagag caattgtgca tgagtaccct gctcaaccac ctgtccctct
     8641 tccatcacca gaatgtttcc ggccccggcg atggtggata aacggtgagc gatgataatc
     8701 accgtccggt tgtgaaccag gttatcgatc gctttttgca ccgccagctc gctttcaata
     8761 tccagcgcgg cagtcggttc atcgagaatg acgaccggcg cgtttttcaa taacgctctg
     8821 gcaatggaaa tccgctggcg ctcgccgccc gatagctggc cgcccatctc tcccattggc
     8881 gtcagccagc cttgcggaag acgggaaata aactcaaggc actgcgccgc gcgggcggcc
     8941 tcttctacct cctgccgcgt cgcctgtggg cgcgcgatac ggatattcgc cagcagcgtg
     9001 tcatcaaaca gccagacatc ctggaaaaca acagaaatca ggctattgag ctgttccggc
     9061 gtcaggcggc gaatatcgac gccgccaata gaaatctgcc cttgctgcgg atcggcatag
     9121 cgcattaaca gtttggtgac cgtagttttg cctgcgccgg aggcacccac cagcgcgctc
     9181 atactggctg ccgggaacgt caaagaaaca tgattaagcg cgtggccgtc gccttcttcg
     9241 tagcgatagc tgacgttgtc aaagcggata tcgtaacgtt ccggcatctc gctttgctct
     9301 gcgacgggaa gcggtgctat cgccataaac cgctcaatcc gttgcagggc gctggcgatc
     9361 agttccacaa ccgaggtgta gctgataaac atcgccatcg gttctgcgaa gcgcataatc
     9421 atcgcgacgg cggcaatcaa aaaggcgagg ttcagagtgc ccgtcactac ccagacgatc
     9481 ccggataaca ccaccacctg taggcccaac tccacgacgc tggcgatcag catcgtcgcg
     9541 ccagcgccct gacggtgagt gcgggtctgt aagttttcca gcgcattgaa atgcgccagc
     9601 agcgcccggc ttttatcggc atcgctgccg caggtgcgca ataccatcat cccctgagca
     9661 aattcaacga tatcgccgct cagacgctgg tgcgcttccc ccagcgtctg catttgtcgc
     9721 cgcatcgccg ggcggcgcca gtaataaaac ggcaccagca gagggaagat cagcaacatc
     9781 accagcccca gccgccagtc tatccacaat gtcgccagcg acgccgtcag cggcgtgaca
     9841 atggtgagca gcaaaatatt ggctatcgca ataacataat tgaggttttc atccacgctg
     9901 cccagcagca aggcgttcat ttcacccgcc ctgccgcgct ggagcttctc cagcggcacg
     9961 cggcgtaact gctcgccaag tcgcaggcgc aactcatggg tggcctgcgc cagatgacca
    10021 cggtattcaa agcccaggcc ataccagcgt agcaccagcg tcacaattgc ggcgacgctg
    10081 aaggccatag cccagttaag aagttgcggc gcgtctcccc gtaacagcgc atcaatgatc
    10141 ggataaagac aggcaaaggc gatcccctgc atgaatgccg ccagcaacag cgccagcata
    10201 ctgcgtcgca gcatcctggc ctgactgcca acgctggaga taagctggcg ccagttgacg
    10261 cgccaggcca ggttatccgc aggattattg tctttcattt tccaccacct cttcctgtgt
    10321 tccacccggc acccaatgct gcgcctgctg atagtgttgc cagagccgtt gatacaggcc
    10381 gccctgcgcc aacagttgcg tatggttccc catttccctg agctgtccgt cggaaaacag
    10441 caatatcaca tcggcctgag tcaccattga gagacgatgc gcgaccatga tgaccgtccg
    10501 gccacgcatg gccgccgcga gcgccttgat aagcgccgct tcgttttccg ggtcagcaaa
    10561 cgccgtcgcc tcatcgagca ccaggatggg gcgatcctgc aaaagcgccc gggcgatagt
    10621 aatgcgctgc cgctggccgc cggagagaaa taccccacgt tccccgactc gtgtgttgta
    10681 accttctggc agagcgctaa taaaatcatg ggcctgcgcc actctggccg ccgctattac
    10741 cgcctccagc ggcgtatccg gcgcgcccag acgaatgtta ttggctatcg tgtcggcaaa
    10801 aaggaagttg tcctgagaca caaacgagag ttgcttcatc agggtgtccg tctgcatatc
    10861 acgcagatcc acgcctccaa tacggatatg gcctttgtcc gggtcggcgt aacgcagcag
    10921 caagcgcgcc acggtgcttt ttccggcgcc gcttggcccg accagcgcca caatttgccc
    10981 ggcaggcaca tgaaagctca cctcctgcaa cgcggcgcca gtacgcgctt gcggataatg
    11041 aaagctcacc tgctcaaagg taatgctcgc ctcttgcggc tgctggtcag actgcggcag
    11101 cgataactcc ggcatcgcga gaacctgata aatacgctga atgcttaaac gcgtttgcgc
    11161 gaccaggtta ttgagcatca tcattggcat tacggcttcg gccattccgc tgcccagcag
    11221 taaaacggcc acccacgcga taaaatcgaa actgccatag tgcagcaggc cgtatcccga
    11281 ccagatcagg acaaacaggg tcgggagagg attcagaatc gagaaggaaa aacgcgctga
    11341 aaaaccggct ttgcgatacc aggttttgag cacatcgacc cactcttcaa gggctcgttg
    11401 atagcgcaaa aaactggtgc tgccgctatc aaacgttctc accacgggca tggcctgcac
    11461 gaactcaatc accgccgcgc taacctgctc gcgcgcctta tgataacgct gagccatatc
    11521 ttccgaacgc tggcgggcga gcacgagaac aaccgatcca aacgccagta cccccagcgt
    11581 cgcgattgcc agccgccagt ccagccagaa caagataacg attgtcgcca gcggcatgat
    11641 gatcgcgcgg gcatagagcg gcgtgctgtc ggccacaaaa atatgtaacg acttcacgtc
    11701 atccagcatc actttcgcca ctgacccgct gcccatttgc tgtaacacgc caggcggaag
    11761 ctgcaatgct ttacgggcta acctgctgcg cagaatgttc tccagatgaa aagccgcgta
    11821 atgagaggtg ttgaacgcct gtaagcgcag aacaaaagtt aagaccacgc agccgatcac
    11881 gccgcccagc ggccaggccg gaatagcgtc aggcgtcgcg cgaatgtcac gcaggctcca
    11941 cgctagaaaa aggagcgccc ccaggctggt taatgccgcc agccccgcca gcgccatagc
    12001 taaaataacc ttcctgcgaa ccggtgtaat cacctgccag agaggaaatc gggacagcga
    12061 ttcagtattg gatgattgag atgacatggg agtaactgaa tttcctgatg aatttttacg
    12121 gacgccaaaa acgacaattc agggtggcgt tctgagaatt aatgtgaata ataaccatta
    12181 tcaataactc atctacccca ttcggttcta tttatacccg cattggtcta agccacaggg
    12241 agataaccag gtcatgacgg agtcaccgca aacgcaatct gaaatctcta ttcaccagtt
    12301 ggtggtcggg aaacctgcaa acgatggcaa tattcctgct cagtgtgaac tgctgcgctg
    12361 ttcgttgcag gaaggtatgg atattttgct ctggaggggc cattttgcgc ggcctgagac
    12421 gttgcagcta cacgacgatc tgggcaggat taacttctcg tgcatcctgg aaggcacatc
    12481 gcgctttgcg attcagggac tccggcgcca caccgactgg gagcttgcgc gcaatcgcca
    12541 ttacattacc catacgccag actgtcgcgg cagcgcctcc tattgtggcc gattcgagag
    12601 cattaccctc tccttcagcc ctgcaaccct cgcgttgtgg gtgccggata ttagcgcgga
    12661 cattaagaat aagatcgact cccactgctg ttgccagcag cagcgttgta atgctgaaac
    12721 ccacttaacg gctcaggcct tgcgtcacgc gctgatgcgc atgcacggcg gcttcagtca
    12781 tgaacaaaag ccgtcgacgc tatggttgca ggggcaaagt ctggtcatgc tcagtctggt
    12841 gctggatgaa catcgcgaag acgccagttg cctctcctgc cacttcaacc cgatggaacg
    12901 ccagaaactg ctgcgggcga aggatctgct gctggctgat ctgacgcaag cgccgggcgt
    12961 cgcggagctg gccagagagt ccggtctgag cgttctcaaa attaagcgag gcttccgcgt
    13021 tctgttcaac aacagcgtct atggcctgtt tcaggctgaa cgaatgcagg aagccagaag
    13081 acgcctggcc aacggcaata cctccgtcat gacggtggcg gccgatctgg gctatgccaa
    13141 cgccagccat ttctctgccg ccttccagaa acagtttggc gtaacccctt cgacctttaa
    13201 acgcgtgatg taaccggggt cgcgcccccc taaactcctc cctgacagag gcccggatac
    13261 cccatccggg cctctgttct ttccgcctgt taccaacccg aaacgggcat aaataaaccc
    13321 gtttcgggta gcatccaatt gttaataatt attattctca tatgagcaat gcttttcggt
    13381 aagacgtgcc atcaggagga agaatgattt ctggcgcacc atctcaggat tcgctgttac
    13441 cggacaaccg ccacgcggct gattaccaac aattacgcga gcggctcata caggaactga
    13501 atttaacgcc gcagcagtta catgaagaga gcaacctgat ccaggccggc ctggattcca
    13561 taagattgat gagatggtta cactggtttc gtaaaaatgg ctaccgcctt acccttcgcg
    13621 agctgtatgc cgcccccacg ctggcggcat ggaaccagtt aatgctcagc cggtcgcctg
    13681 agaacgcgga agaagaaacg ccgcccgacg aatcatcctg gccgaacatg accgaaagta
    13741 cccccttccc attgacgcca gtacagcacg cctacctgac gggccgcatg ccggggcaga
    13801 cgcttggcgg cgtgggttgc cacctgtatc aggagtttga aggccattgt ctgacggcgt
    13861 cgcagctgga gcaggccatc acgaccttgc tgcaacgcca cccaatgctg catatcgcct
    13921 ttcgccccga cgggcagcag gtctggctac cgcaacctta ctggaacggc gtcaccgttc
    13981 atgatttacg ccataacgac gctgaaagcc gccaggccta tctggacgca ctgcgccagc
    14041 gcctgagcca ccgtctttta cgcgtggaaa tcggcgaaac gtttgatttt cagctgacgc
    14101 tcttgccgga caatcgccac cgcctccatg tcaatattga cctgctgatt atggatgcct
    14161 ccagctttac gcttttcttc gatgagctta acgccctgct ggccggagaa tcgctgccgg
    14221 ctatcgacac ccgctatgat ttccgctcgt atttgctgca ccagcagaag atcaatcaac
    14281 cactgagaga cgacgcgcgc gcttactggc tggcgaaagc atcgacgctt ccccccgcgc
    14341 ccgtcttgcc gctggcctgc gaacccgcca cgctacgtga agtccgtaat acccgacgcc
    14401 gcatgattgt cccggcaaca cgctggcacg cctttagcaa ccgggccggc gagtatggcg
    14461 tgacgccgac aatggcgctg gcgacctgtt tttctgccgt gctggctcgc tggggcggcc
    14521 tgacgcgact gctgcttaac atcaccttat tcgaccgcca gccgctgcac ccggcggttg
    14581 gcgcgatgct tgccgacttc accaatattc ttctgctgga taccgcctgc gatggcgata
    14641 ccgtcagcaa cctggcgcgt aaaaaccagc tcacgtttac ggaggactgg gagcatcgcc
    14701 actggtccgg cgtcgaatta ctccgtgaac tcaaacgcca gcagcgctac ccccacggcg
    14761 ccccggtggt atttaccagc aatctggggc gttccctcta cagcagccgc gcagaatcgc
    14821 cgttgggcga gccggaatgg ggcatctcgc aaacgccgca ggtctggata gatcatctgg
    14881 cgttcgagca tcacggcgag gtctggctac aatgggacag caacgacgcg ctgttccctc
    14941 cggcgttagt cgaaacattg ttcgacgcct actgccagtt gattaaccaa ctctgcgatg
    15001 acgaaagcgc ctggcaaaag ccgttcgcag atatgatgcc cgccagccag cgcgcgatac
    15061 gcgaacgggt caacgccacc ggcgccccca ttcccgaagg cttgctgcat gaaggcattt
    15121 tccgtatcgc tctgcaacag ccgcaggcgc tggcggtaac ggacatgcgt tatcagtgga
    15181 attatcatga gctgacagac tatgcccgcc gttgcgcggg caggttaatc gagtgcgggg
    15241 ttcagcccgg cgataatgtg gctatcacga tgtcgaaagg cgcaggacaa cttgttgcgg
    15301 ttctggccgt cctgctggcc ggggcggttt acgttccggt ttcgctggat cagcctgccg
    15361 cacggcgcga gaaaatctac gctgacgcca gcgtccggct ggtgctcatt tgtcagcacg
    15421 acgccagcgc cgggtcagac gatattcccg tccttgcctg gcagcaggcc attgaggcgg
    15481 agccgatcgc caacccggta gtacgcgccc ccacgcaacc ggcctacatt atctacacct
    15541 ccggctctac cggtacgccg aaaggggtag tcatttctca ccggggagcg cttaacacct
    15601 gttgcgatat caatacccgc tatcaggttg gcccgcatga cagggtgctg gccctctccg
    15661 ccctacattt tgatttatcg gtttacgaca tttttggcgt actgcgcgcg ggcggcgcgc
    15721 tggtgatggt gatggaaaat caacggcgcg atcctcacgc atggtgtgag ctgatccagc
    15781 gccatcaggt cacgctctgg aacagcgtcc cggcgctgtt cgatatgctg ctgacctggt
    15841 gtgaaggttt cgccgacgcc acgccggaaa acctgcgcgc agtgatgctt tccggcgact
    15901 ggatcgggct tgacctcccc gcccgttatc gggccttccg gccacaagga caatttatcg
    15961 cgatgggcgg cgccaccgag gcgtctatct ggtctaacgc ctgcgaaatt cacgacgtcc
    16021 ccgcccactg gcgctccatc ccttacggtt ttccgctaac caaccaacgc taccgggtgg
    16081 tggatgaaca gggccgggac tgccctgact gggtgccggg tgaattatgg attggcggca
    16141 ttggggtcgc ggaaggctat ttcaacgatc ccctgcgtag cgagcagcaa tttttgacgc
    16201 tcccggacga gcgctggtat cgcaccggcg atctcggctg ctactggcca gatggcacaa
    16261 tcgagttcct cggtcgtcgc gacaagcagg tcaaagtcgg aggatatcgc atcgagctgg
    16321 gcgaaatcga aagcgcgctc agccagctgg cgggggtgaa acaagcaacc gttctggcga
    16381 tcggcgaaaa agaaaaaacg ctggcggcat acgttgttcc tcaaggcgag gctttttgca
    16441 ttaccgatca tcggaacccg gcactgccgc aggcgtggca cacgcttgcg ggaacgttgc
    16501 cctgttgcgc catctcgcca gagatctccg cagaacaggt agccgatttc cttcagcatc
    16561 gcctgctaaa actgaagccg ggtcacaccg ctggcgccga tcctctcccc ctgatgaact
    16621 cactcgctat ccagccgcgc tggcaggccg tggtggaacg ctggttagca tttctggtga
    16681 cacaacggcg actgaagccc gctgctgaag gttatcaggt ctgtgctggt gaagaacgcg
    16741 aggatgagca cccgcacttc agcggacatg atttaacgtt atcgcaaatt cttcgcggtg
    16801 cccgtaacga actgtcgtta ctgaacgacg cgcagtggtc gccggaaagc ctggccttta
    16861 accatccggc cagcgccccg tatattcagg aactggcgac aatttgccaa cagcttgcac
    16921 agcgcttaca gcgcccgata cgcctgcttg aggtgggaac ccgcactggc cgcgccgcag
    16981 aatcgctgtt agcacagctc aacgccggac agattgagta tgtcgggctt gagcagagcc
    17041 aggagatgct gctgagcgcc cggcagaggc tcgccccctg gcctggcgcc cgtctgtccc
    17101 tctggaatgc agacacgctt gcgacgcacg ctcactcggc ggacattatc tggcttaata
    17161 acgccctgca tcgtctgctg ccggaagatc ccgggctcct tgcgacatta caacagcttg
    17221 ccgttcccgg cgcgctgctc tacgtgatgg agtttcgcca gttaacgccg tccgccctgc
    17281 tcagcacgct cctgttaacc aatgggcagc cggaggcctt gctgcataac agcgccgact
    17341 gggcggcatt atttagcgcg gccgccttca actgtcagca tggcgatgag gtcgcggggt
    17401 tacaacgctt cctcgtacaa tgtcctgaca ggcaggtgcg ccgcgatccc cgtcaacttc
    17461 aggccgccct cgctggacgt ctgccggggt ggatggtgcc gcaacggatc gtcttcctcg
    17521 acgccttacc gctgacggct aacgggaaaa ttgactacca ggcgctgaag cgtcgtcata
    17581 cccctgaagc ggaaaacccg gccgaagcgg atttacccca gggcgacatt gaaaaacagg
    17641 ttgccgccct ctggcagcaa ctcttatcaa ctggcaatgt caccagagaa accgacttct
    17701 tccagcaagg cggcgatagc ctgctggcga cccgtctgac cgggcaactt catcaggcag
    17761 gttatgaagc gcaattaagc gacctgttta atcatccccg gctggcggat tttgccgcca
    17821 cactgcggaa aaccgacgtc ccggtcgaac aaccattcgt ccactcccct gaagatcgct
    17881 accagccctt tgcgcttacc gacgtgcagc aggcttacct ggtggggcgt cagccgggct
    17941 ttgccctggg cggcgtcggc tcacatttct ttgttgaatt tgaaattgcc gatctggacc
    18001 tcacccggct ggagacggtc tggaaccgat taatcgcccg ccacgatatg ctgcgcgcca
    18061 tcgtgcgtga tggacagcaa caggtgctcg aacagacgcc cccctgggtg atacccgcac
    18121 acaccctcca tacgcctgaa gaggcgttgc gggtgcgcga aaaactggcg catcaggtac
    18181 tcaaccccga agtgtggccg gtattcgatc tccaggtcgg atacgtggac gggatgcctg
    18241 cccgcctgtg gctgtgtctg gataacctgt tgcttgacgg tctcagcatg cagatcctgc
    18301 tggcggagct ggagcacggc taccgctacc cgcaacagct gcttccgccg ctgcccgtca
    18361 ccttcaggga ttatctgcaa caaccctcgc tacagtcgcc caatccagat tctctggcat
    18421 ggtggcaggc gcagcttgat gatattcctc cggcgcctgc gttgccgctg cgctgcttgc
    18481 ctcaggaggt tgaaacaccg cgcttcgccc gcctgaacgg cgcgctggac agcacgcgct
    18541 ggcatcggct gaaaaaacgg gcggctgacg cccatctcac cccgtcggcc gtactgttgt
    18601 cggtgtggtc aacggttctc tctgcatgga gtgcacagcc tgagttcacg cttaacctta
    18661 cgcttttcga caggcgaccg ctgcacccgc aaatcaacca gattctgggc gatttcacct
    18721 cgctgatgct gctgagctgg catcccggcg aaagctggct gcacagcgcg cagtcactac
    18781 agcagcggct gagccagaac ctcaaccacc gcgatgtgtc agccatccgc gtgatgcgtc
    18841 aactggcgca acagcaaaac gtgcctgccg ttccgatgcc cgtcgtcttt accagcgcgc
    18901 tgggctttga gcaggataac ttcctcgccc ggcgtaatct gctcaaaccg gtctggggca
    18961 tctcccagac gccgcaggtc tggttcgatc accagattta tgaatccgaa ggcgaactgc
    19021 gctttaactg ggattttgtc gccgcgctgt ttcctgccgg gcaggtggag cgccagtttg
    19081 aacagtattg cgcattgcta aaccgaatgg ccgaggatga aagcggctgg caactgccgc
    19141 tcgccgcgct ggtgcctccc gttaaacacg cagggcaatg cgcagagcgc tcaccgcgcg
    19201 tatgccctga gcaatctcag ccacacattg cggcggacga gagcaccgtc agcctgattt
    19261 gcgacgcctt ccgcgaggtg gttggcgagt ctgtcacgcc cgcagaaaac ttctttgagg
    19321 cgggcgcaac gtcgctgaat ctggtgcaac tgcacgtttt attacaacgt cacgaatttt
    19381 ccaccctgac gttgcttgac ctcttcaccc acccttctcc tgttgccctg gccgattatc
    19441 tggccggcgt caccacggtg gagaaaacaa aacgacctcg ccctgttcgc cgtcgtcagc
    19501 ggcggatata gcgcgaagca aactgatttt ccccggaacg ccatcgcgaa cgcatggcgt
    19561 tccattgact ttgtgaatct taggaaacgg gaccgattat ggataacttg cgcttctctt
    19621 ctgcgccgac agcagattcc attgatgcat cgatcgctca acactacccg gactgcgaac
    19681 ctgtcgcggt tatcggctac gcctgccatt ttcctgaatc gccggatggc gaaacgttct
    19741 ggcaaaatct gctggaaggt cgtgaatgca gccgacgctt tacgcgcgaa gagcttctgg
    19801 ccgtcggtct ggatgccgcc atcattgacg atcctcatta tgtcaatatc ggtacggtgt
    19861 tagacaacgc cgactgcttc gacgccaccc tgtttggcta ttcgcgacag gaagcggagt
    19921 cgatggaccc gcagcagcgc ctatttttgc aggcggtctg gcatgcgatg gaacatgccg
    19981 gttatgcccc cggcgccgtc ccccataaga ccggcgtttt cgcctcttcc cggatgagta
    20041 cctaccccgg tcgcgaagca ttgaacgtga cagaagtcgc gcaggtaaaa ggtctgcaat
    20101 ctctgatggg caatgataaa gactatattg ccacccgcgc cgcgtacaaa ctcaacctgc
    20161 acggcccggc gttatcggta cagaccgcct gctccagctc gctggttgcc gtgcatctgg
    20221 cctgtgaaag cctgcgcgca ggcgaatccg atatggcggt tgccggcggc gtggcgctct
    20281 ctttccccca gcaggcaggc taccgctacc agcccggaat gattttctct cctgatggtc
    20341 actgtcgtcc ctttgacgcc tcggctgagg gcacctgggc cggtaacggt ctcggctgcg
    20401 tggtgctgcg tcgcctgaga gacgcgctgc tgtcaggcga tccgattatc tcggtgatcc
    20461 tctccagcgc ggtcaacaac gacggcaaca gaaaggtcgg ctataccgcc ccttccgtcg
    20521 cagggcaaca ggcagtcatc gaagaggcgt taatgctggc ggccatcgac gacaggcagg
    20581 taggttacat tgaaacccac ggcaccggca caccgctggg cgacgcgatt gaaattgaag
    20641 cgttacgcaa cgtctatgcg cctcgcccgc aggatcagcg ctgtgcgctc ggttccgtga
    20701 aaagtaacat gggccatctg gataccgcgg cgggcattgc cggactgctg aaaaccgttc
    20761 tggcagtcag tcgcgggcaa attcctccct tactgaattt tcacaccccc aacccggcgc
    20821 tgaaacttga agagagcccc tttaccatac cggtgtcggc acaggcatgg caggacgaaa
    20881 tgcgctatgc gggcgtctcc tcctttggta ttggcggcac caactgccat atgatcgtcg
    20941 cctcgctgcc cgacgcgctc aacgcgcgcc tccccaatac ggatagcggc agaaaaagta
    21001 ccgcgctgct gctcagcgcc gccagcgaca gcgcgttgcg gcggctggcg acggattatg
    21061 ccggggcgct gagagagaat gcggatgcca gctctctggc cttcacagcc ctgcacgcgc
    21121 gccgtctcga tctccccttc cgcctggcgg cgccattaaa ccgtgaaacc gccgaggcgc
    21181 tcagcgcctg ggccggtgag aaatcggggg cgctggttta cagcggccac ggcgccagcg
    21241 gcaagcaggt gtggctgttt accggccagg gctcgcactg gcgcactatg ggtcaaacga
    21301 tgtaccagca ctcaacggcg tttgccgaca cgctggatcg ctgtttttcc gcctgtagcg
    21361 aaatgctcac gccgtcactg cgcgaagcga tgtttaaccc cgattcggcg caactggaca
    21421 atatggcctg ggcgcagccg gcgattgtcg cgtttgaaat cgcgatggcg gcgcactggc
    21481 gtgctgaagg actgaagcca gacttcgcca ttgggcattc cgtcggtgaa tttgccgctg
    21541 ctgttgtctg cggacactat acgattgaac aggtcatgcc actggtttgt cggcgcggcg
    21601 cgctaatgca gcagtgcgca agcggcgcga tggtggcggt atttgcagac gaagacacgc
    21661 tgatgccgct ggctcgccag tttgagctgg atctcgccgc caataacggt acgcaacata
    21721 cggtattttc cggaccggaa gcccgtctcg cagtattttg cgccacgctc tcgcagcatg
    21781 acattaacta tcgtcgcctg agcgtaaccg gtgcggcgca ctccgcttta ctggagccga
    21841 tactcgatcg gttccaggac gcctgcgcgg gactgcacgc ggagccgggg caaataccga
    21901 ttatttccac gctcaccgcc gacgtcattg atgagtcaac gctcaaccag gcggattact
    21961 ggcgccgaca catgcgccag ccggtgcgtt ttatccagag tattcaggtg gcgcatcagc
    22021 tcggcgcccg cgtttttctg gagatggggc ccgatgccca gttggttgct tgcgggcagc
    22081 gcgaataccg cgataacgca tactggatag ccagcgcccg gcgtaacaaa gaggcgagcg
    22141 atgtcctcaa tcaggccctg ctccagcttt acgctgccgg cgtcgcccta ccgtgggccg
    22201 acctgctggc gggcgatgga caacgtatcg ctgcgccatg ttatccgttt gatactgagc
    22261 gttactggaa agagcgcgtc tccccggcct gcgagcctgc cgacgcagcg ctgtctgccg
    22321 ggctggaggt ggcgagtcgc gccgcgacag cgctcgatct ccctcgcctg gaagcgctta
    22381 aacagtgcgc cacgcgactg cacgccatct acgtcgatca actggtacaa cgctgtaccg
    22441 gcgatgccat tgagaacggc gtggacgcca tgaccatcat gcgccgtgga cgtctgctgc
    22501 cccgctacca gcagctactc cagcgcctgc tgaataactg cgtggtcgac ggcgattacc
    22561 gctgcaccga cgggcgatac gtccgcgccc gccccattga acatcaacag cgggaatcac
    22621 tgctgacgga acttgccggt tattgtgaag gttttcaggc tattcccgac accatcgccc
    22681 gtgccggcga tcggttatat gaaatgatga gcggcgcgga agaaccggtg gcgattatct
    22741 tcccgcaaag cgcctccgac ggcgtggaag tgctgtatca ggaattcagc tttggccgct
    22801 atttcaacca aatcgccgcc ggggtattac gcggcattgt ccagacgcgt cagccccgcc
    22861 agccgttgcg tattcttgaa gttggcggcg gaaccggcgg caccaccgcg tggctgctgc
    22921 cggaactcaa cggcgttccg gcactggagt accatttcac cgatatctcg gcgctgttca
    22981 cccgtcgcgc ccagcagaaa ttcgccgact atgattttgt gaagtatagc gagctggatc
    23041 tcgaaaaaga ggcgcagtct cagggtttcc aggcacagtc ttacgatctt atcgtggcag
    23101 cgaacgtgat tcacgccacc cgccatattg gccgcacgct cgataatctg cgccccctgc
    23161 tcaagccggg cgggcgcctg ctgatgcgcg aaatcaccca gccaatgcgt ctgtttgact
    23221 tcgttttcgg cccgctggtt cttccgctac aggatctcga cgcccgcgaa ggtgagttat
    23281 tcctcaccac cgctcagtgg caacaacagt gccgccacgc cggattcagc aaagtggcgt
    23341 ggctaccgca ggatggcagc ccgaccgccg ggatgagcga acatatcatt ctcgccacgc
    23401 tgcccggtca ggcggttagc gccgtaacat tcaccgcgcc atcagaaccc gtgttggggc
    23461 aggcgctgac ggataacggt gattatctcg ccgactggtc tgattgcgca ggtcagcccg
    23521 aacggtttaa cgcccgctgg caggaggcct ggcgtctgct ttcacagcgt catggcgacg
    23581 ctctgcctgt ggaaccgccc cccgtcgccg ccccggagtg gctggggaag gttcgcttaa
    23641 gctggcaaaa cgaagccttt tcccgcggtc agatgcgcgt tgaagcccgt catcctgctg
    23701 gcgagtggct gccgctatcg cccgccgcgc ctcttcctgc gccgcagacg cattatcaat
    23761 ggcgctggac gcccctcaac gtcgccagca ttgaccaacc gcttaccttt agcttcagcg
    23821 ccggtacgct tgcgcgcagc gacgagctgg cgcaatacgg catcattcac gatccgcacg
    23881 cctcttcgcg actgatgatt gttgaggaga gcgaggatac gctggcctta gcggagaaag
    23941 tgatagcagc gctcaccgcc agcgcagccg gattgattgt ggttactcgc cgcgcgtggc
    24001 gagtcgagga aaatgaagca ctctctgcat cccatcacgc gctatgggcc ttgcttcgcg
    24061 tcgcggccaa cgaacagccg gaacggttgc ttgccgccat cgatctcgcc gaaaacaccc
    24121 cgtgggaaac gctgcatcaa gggttgagcg cagtctcact atcacagcgc tggctcgccg
    24181 cacggggtga caccctttgg ctcccttcac tggcgcccaa tacgggatgc gccgctgaat
    24241 taccggcaaa cgtgtttacc ggcgatagcc gctggcatct ggtgaccgga gcgtttggcg
    24301 gattaggccg ccttgccgtg aactggctca gagaaaaagg ggcgcgacgc atcgccctgc
    24361 tggcgccgcg cgtggatgag tcatggctac gcgacgtgga gggcgggcag acgcgcgtct
    24421 gccgttgtga tgtgggcgat gccgggcaac tggccacggt tcttgacgat ctggcggcca
    24481 acggcggcat tgccggagcg attcatgccg ctggcgtatt ggctgacgcg cccttgcagg
    24541 agcttgatga ccaccagctg gctgccgttt tcgcggtaaa agcgcaggcg gcaagccagc
    24601 tgttgcaaac cctgcgcaac cacgacggac gctatcttat tctctactct tccgctgccg
    24661 ccaccctcgg cgcgccgggt cagagcgccc atgcgctggc ctgcggctac ctggacgggc
    24721 tggcccagca gttttccacc cttgatgcgc cgaaaacgct ctctgtcgcc tggggcgcat
    24781 ggggagaaag cggtcgggcg gccacgccgg aaatgctggc gacgctcgcc agccgaggta
    24841 tgggcgcgtt aagcgatgcc gaaggctgct ggcacctgga acaggcggtg atgcgcggcg
    24901 ccccgtggcg actggcgatg cgcgttttta ccgacaaaat gcccccgtta caacaggctc
    24961 tgtttaacat cagcgccaca gaaaaagccg caacgccggt cattcctcct gctgatgaca
    25021 acgcctttaa cggcagcctg agcgatgaaa cagcggtgat ggcatggctg aaaaagcgga
    25081 ttgcggttca gctaaggctg agcgatccgg cgtcactgca tccaaaccag gatctgttgc
    25141 aactcggcat ggactcgctg ctcttccttg aactcagtag cgatattcag cactacctgg
    25201 gcgtacgcat caatgcggaa cgggcgtggc aggatctgtc tcctcatgga ctcacgcagc
    25261 ttatctgttc taagccagag gcgacgcctg ccgcttcgca gccggaagtg ttgcggcacg
    25321 acgccgacga gcgttatgcg cccttccctt tgacgcccat tcagcacgcc tactggctgg
    25381 ggcgaaccca cctcattggc tatggcggcg tcgcctgtca cgtcctgttt gagtgggata
    25441 aacgccacga tgagttcaat ctcgccatac tggagaaagc atggaaccag ctcatcgcac
    25501 gccacgatat gttgcgtatg gtggttgatg ccgacgggca gcagcgaatc ctggcgacaa
    25561 cgccggagta tcacatcccg cgtgacgatc tgcgcgcgct ttccccggaa gaacagcgca
    25621 tcgcgctgga aaaacggcgg catgaactga gctatcgcgt tttgcctgcc gaccagtggc
    25681 ctctttttga gctggtggtc agcgaaatcg acgattgcca ttaccgtctg catatgaacc
    25741 tcgacctttt gcagtttgat gtgcagagtt ttaaagtcat gatggacgac ctggcgcagg
    25801 tctggcgcgg tgaaacgctg gcgccgctcg ctattacctt ccgtgattat gtgatggctg
    25861 aacaggcgcg ccgacagaca tcggcatggc acgatgcctg ggattactgg caggaaaaac
    25921 tgccgcaact gcccttagcg ccagagctgc cggtggttga gacgcccccg gaaacgccac
    25981 acttcaccac cttcaaatcg acgatcggca agacagaatg gcaggccgtg aaacagcgct
    26041 ggcagcagca aggcgtcaca ccgtctgccg cgctgctcac gctgtttgcc gccacccttg
    26101 agcgctggag ccgtaccaca acatttacgc tgaacctgac gttcttcaat cgccagccga
    26161 tccatccgca aatcaaccag ttgattggtg attttacctc cgtcacgctg gttgatttta
    26221 acttctcagc gccggtgacg ttgcaagagc agatgcaaca gacccaacag cgcctctggc
    26281 aaaacatggc gcacagtgaa atgaacggtg ttgaggtgat ccgtgagctg ggccgcctgc
    26341 gcggatcaca acgtcaaccg ctgatgccgg tagtgtttac cagtatgctg gggatgacgc
    26401 tggaaggcat gactatcgat caggcgatga gccatctgtt cggcgaaccc tgctatgtat
    26461 tcacgcaaac gccgcaggtc tggctggatc atcaggtcat ggagagcgac ggcgagttga
    26521 tgtttagctg gtactgcatg gacaacgtgc tggaacccgg cgctgccgag gcgatgttta
    26581 atgactattg cgccatcctg caagccgtca tcgccgcccc tgaaagcctg aagactctcg
    26641 ccagcggcat cgccgggcac attccccgcc gacgctggcc gctgaacgcg caggcggact
    26701 acgacctgcg ggatattgag caggcgacgc tcgaataccc cggcatccgg caggccagag
    26761 cggaaataac cgaacagggc gcgttgacgc tggatatcgt gatggccgac gatccgtcgc
    26821 catcagcggc gatgcctgat gagcacgaac ttacccaact ggcgctgccg ttgcctgagc
    26881 aggcgcagct tgatgagctg gaggcgacct ggcgctggct ggaggcgcgt gcgctacagg
    26941 ggatcgcggc tacgctaaat cgtcacggcc tgtttaccac gccggagatc gcccatcgct
    27001 ttagcgcaat agtacaggcg ctgtccgcgc aagcgtctca ccagcgtctg ctgcgccagt
    27061 ggctacagtg tctgacggaa agagagtggt taatccgcga aggtgaaagc tggcgctgcc
    27121 gcattccgct cagcgagatt cctgagcctc aggaagcgtg cccgcaaagc caatggagcc
    27181 aggcgctggc gcagtatctg gaaacctgca tcgcccggca cgacgccctc ttctccgggc
    27241 ggtgttctcc gctggaattg ctgttcaacg agcagcatcg cgttaccgac gcgctgtatc
    27301 gcgacaaccc cgccagcgcc tgtctgaatc gctataccgc gcagattgcc gccttgtgca
    27361 gcgcagaacg gattctggag attggcgccg gaaccgcagc cactaccgcg ccggtgctga
    27421 aggccacgcg gaacacgcgg cagtcgtacc acttcacgga cgtctccgcg cagttcctca
    27481 atgacgccag agcccgtttc catgatgaat cgcaggtgtc ttatgccttg ttcgacatca
    27541 accagccgct ggatttcacc gcccacccgg aggcgggtta cgacctgatc gttgccgtca
    27601 atgtgctcca cgacgccagc catgtcgtcc agacgttgcg cagattaaaa ctgttgctga
    27661 aagccggcgg acgtttgctg atcgttgaag cgacggagcg aaacagcgta ttccagctgg
    27721 cgagcgtggg ctttattgag ggattaagcg gataccgcga tttccgccgc cgggatgaga
    27781 aaccgatgct cacccgctcc gcatggcagg aggttctcgt tcaggccggg tttgcaaacg
    27841 agctggcgtg gcccgcgcag gaatcgtcgc cgctgcgcca gcatctgctg gtggcgcgtt
    27901 cgcctggcgt aaatcgcccg gataaaaaag ccgtgagccg ctatttacag cagcgctttg
    27961 gcaccggtct gcccatttta cagatccggc aaagagaagc gttatttacg ccgctgcatg
    28021 ccccgtctga tacgccgact gagccagcca aacccacgcc agttgccggg gggaatccgg
    28081 cgctggaaag acaggtggct gaactctggc aatcgctgct gtctcgcccc gtggcaaggc
    28141 atcacgactt tttcgaactg ggtggcgaca gcctgatggc gacaaggatg gtcgcgcagc
    28201 taaaccggag agggattgct agggctaacc ttcaggatct gttcagccat tcgacgctga
    28261 gcgacttctg cgcccatcta caggcggcta cgtcaggaga ggacaacccg ataccccttt
    28321 gccagggcga cggtgaggaa accctgtttg tcttccacgc ttcagacggc gatatcagcg
    28381 cctggctgcc gctcgctagc gcgttgaaca ggcgcgtttt cggcctgaaa gcaaaatcgc
    28441 cgcagcgctt tgccacgctc gaccagatga tcgatgagta tgtcgggtgc atccgtcgtc
    28501 agcagcctca cggcccttat gtgctggcgg gttggtcgta tggcgcgttt cttgcggcgg
    28561 gcgccgcaca gcgcctgtac gccaaaggcg agcaggttcg gatggtgtta atcgatcccg
    28621 tgtgccgaca ggatttctgt tgcgaaaacc gggcggccct gctgcgcctg ttagccgaag
    28681 gacaaacgcc tctggcactg cccgaacatt tcgaccagca gacgcccgac agccagcttg
    28741 ccgactttat cagcctcgct aaaacggccg gtatggtgtc gcaaaacctg acgctgcaag
    28801 cggcagaaac gtggctcgac aacatcgcgc atctgctgcg tttactgact gagcatacgc
    28861 cgggcgaaag cgttccggtc ccctgtctca tggtgtatgc cgccgggaga cccgcgcgct
    28921 ggacgccagc agaaaccgag tggcagggct ggataaacaa cgccgacgac gctgtgattg
    28981 aagccagcca ctggcaaatc atgatggaag ccccccacgt tcaggcttgt gcgcaacaca
    29041 ttacgcgctg gctttgcgca acctcaacgc aaccggagaa cacgttatga tgccgtccgc
    29101 ctccccaaaa caacgcgtac tgattgtggg cgccaaattt ggcgaaatgt acctgaatgc
    29161 ctttatgcag cccccggagg ggctggaact ggtcggcctg ctggcgcagg gaagcgcccg
    29221 ttcaagagag ctggctcatg cgtttggcat tccgctgtat acctcgccgg aacagataac
    29281 caggatgccg gatatcgcct gtattgtcgt gcgttcgacc gtcgccggag gaaccggtac
    29341 gcagcttgcc agacactttc tgacgcgcgg cgtacacgtc attcaggagc atcccctcca
    29401 cccggatgac atcagttcct tacaaacgct ggcgcaggaa cagggctgct gctattgggt
    29461 aaacacgttt tatccgcata cgcgcgcggg acgcacatgg cttcgcgatg ctcagcagct
    29521 gcatcgctgc ctggctaaga cgccgccggt agtccacgcc accaccagcc gacagttgct
    29581 caactccact ctggatttgt tgttgctggc tctgggcgtt gatgccgccg ccgtggagtg
    29641 cgacgtggtt ggcagcttta gcgattttca ctgtctgaga ctcttctggc cggagggaga
    29701 agcctgcctg ctgcttcagc gctatctcga tcctgacgat ccagatatgc atagccttat
    29761 catgcaccgc ctgctgctgg gctggccgga aggtcatctt tcgctggagg cgagctacgg
    29821 ccccgtcatc tggtcatcca gcctgtttgt cgcagaccat caggagaacg cccacagcct
    29881 ctaccgcaga ccggagatcc tgcgcgatct gctgggtctg acgcgcagcg cggcgcccct
    29941 gagctggcgc gactgctgcg aaaccgtcgg gccggagggc gtcagctggt tgctacacca
    30001 gttgcgcagc catctggcgg gcgaacatcc accagcggcc tgccaaagcg tacatcagat
    30061 cgcgttatca cgtttatggc agcagatttt acgtaagacc ggcaatgcgg agatcagacg
    30121 cctgacaccg ccgcaccacg accggttagc cggtttctac aacgatgatg ataaggaggc
    30181 gctgtgacgc aatctgcaat gtgcatcccg ctgtggcccg cccggaacgg caatactgcg
    30241 catctggtca tgtgcccttt cgctggcggc agcagtagcg cgtttcgcca ctggcaagct
    30301 gagcaactgg ctgattgcgc gctttctctg gtgacctggc cggggcgcga tcgccttcgc
    30361 catctggaac cgctcagaag cattacacaa ctggcggcac tgctggcgaa cgagctggaa
    30421 gcatccgtat cgcctgacac gccgctttta ctcgccgggc acagcatggg ggcgcaggtg
    30481 gcgtttgaaa cctgccgact tctggagcaa cgggggcttg cgccacaagg actgattatt
    30541 tccgggtgcc atgccccgca tctgcattct gaacgccagc tcagccatcg cgatgatgcc
    30601 gactttatcg ctgagctgat agacattggc ggatgttctc ctgaactgca ggaaaaccag
    30661 gaattaatgt cgctgtttct tcctcttctg cgcgctgatt tttacgccac cgagagctat
    30721 cactacgact cgcccgacgt ctgtccgccg ctgcgcacgc ctgcgctgtt attgtgcggc
    30781 agccacgatc gcgaagcctc ctggcagcag gtcgatgcct ggcgtcagtg gctgagccac
    30841 gttacaggcc cggtggtgat tgacggcaat catttctatc ccattcaaca agcccggtcc
    30901 ttttttacgc agattgtccg ccattttccc cacgcatttt ctgcaatgac cgcgttgcaa
    30961 aaacagccca gtacttcaga aaggtgacgc atgaattctt cctttaaatc tctgattgaa
    31021 cagtatccct tacccattgc cgaacagttg cgccactggg cggcccgtta tgcctcgcga
    31081 attgccgtcg ttgatgcaaa ggggtcgtta acctacagcg cgcttgatgc acaagttgac
    31141 gaacttgccg caggtctgtc atcactgggt ttgcgttcgg gggagcatgt aattgtgcag
    31201 cttcccaacg acaacgcgtt tgttaccctg ctgttctcct tgttaagact gggcgttatc
    31261 cccgtgctgg cgatgccctc gcaacgggcg ctggatatcg acgcgctgat tgagctggcg
    31321 caacccgtcg cttacgttat tcaaggggaa aaccacgcag agctggcccg acagatggcg
    31381 cacaaacacg cctgcttgcg tcatgttctg gtcgctggag agaccgtgag cgacgatttt
    31441 acgccgctct tctcccttca cggtgagcga caggcatggc cgcagcctga tgtttccgcc
    31501 accgcgttgt tgttgctctc aggcggcaca accggcacgc ccaaactcat cccgcgccga
    31561 catgccgact atagctataa cttcagcgct tctgctgaac tgtgcggcat cagccaacag
    31621 agcgtgtatc tcgccgtcct cccggtggcg cataactttc cgctggcctg ccccggtatt
    31681 ctgggaacgc ttgcctgcgg cggaaaagtg gtgctgaccg acagcgccag ctgtgatgag
    31741 gtgatgcctt taatcgcgca ggaaagagtg actcacgtcg ccctggttcc ggcgctggcg
    31801 caattatggg tgcaggccag ggagtgggaa gacagcgacc tttcgtcgct gcgcgtcatt
    31861 caggcaggcg gcgcccggct cgacccgacg cttgctgagc aggttatcgc cacctttgac
    31921 tgtaccctgc aacaggtttt cggtatggcg gaaggcctgc tctgttttac ccggctggac
    31981 gatccgcatg ccaccattct ccacagccag gggcgcccgt tgtcccctct ggatgaaatc
    32041 cgcatcgttg atcaagacga gaacgacgtc gcgccgggcg aaaccgggca attgttaacg
    32101 cgcggccctt ataccatttc gggctattac cgcgcccctg cccacaacgc gcaggccttt
    32161 accgcgcaag ggttttaccg cacaggcgac aatgtcaggc tggatgaggt agggaacctg
    32221 cacgttgagg gacgcataaa agagcagatc aaccgcgccg gagaaaaaat agccgcggct
    32281 gaagtggaat cggcactgct gcgtttagcg gaagtgcaag attgcgcggt ggtcgccgcg
    32341 ccggacacgc tgcttggcga gcggatttgc gcgtttatca tcgcgcagca ggtgccaact
    32401 gactatcagc agttgcgtca acaactgacc cgtatggggc tcagcgcgtg gaaaattcct
    32461 gaccaaatcg agtttctgga ccactggccg ctcaccgccg tcggcaagat agacaaaaaa
    32521 cgcctgacgg ctctcgccgt cgaccattat cgccattctg cccaataagc gcaaaccgac
    32581 ccgaaacagg ttgaaataaa cccgtttcgg gtagcaccac tattagaaat agttatcatt
    32641 ttcaattcac cattgtcggt atttttggcg tttcgccgtc ttacagggac tcacaacaat
    32701 gaaaatgaca cggctttatc ctctggcctt ggggggatta ttgctccccg ccattgctaa
    32761 tgcccagact tcacagcaag acgaaagcac gctggtggtt accgccagta aacaatcttc
    32821 ccgctcggca tcagccaaca acgtctcgtc tactgttgtc agcgcgccgg aattaagcga
    32881 cgccggcgtc accgccagcg acaaactccc cagagtcttg cccgggctca atattgaaaa
    32941 tagcggcaac atgctttttt cgacgatctc gctacgcggc gtctcttcag cgcaggactt
    33001 ctataacccc gccgtcaccc tgtatgtcga tggcgtccct cagctttcca ccaacaccat
    33061 ccaggcgctt accgatgtgc aaagcgtgga gttgctgcga ggcccacagg gaacgttata
    33121 tggcaaaagc gctcagggcg ggatcatcaa catcgtcacc cagcagccgg acagcacgcc
    33181 gcgcggctat attgaaggcg gcgtcagtag ccgcgacagt tatcgaagta agttcaacct
    33241 gagcggcccc attcaggatg gcctgctgta cggcagcgtc accctgttac gccaggttga
    33301 tgacggcgac atgattaacc ccgcgacggg aagcgatgac ttaggcggca cccgcgccag
    33361 catagggaat gtgaaactgc gtctggcgcc ggacgatcag ccctgggaaa tgggctttgc
    33421 cgcctcacgc gaatgtaccc gcgccaccca ggacgcctat gtgggatgga atgatattaa
    33481 gggccgtaag ctgtcgatca gcgatggttc accagacccg tacatgcggc gctgcactga
    33541 cagccagacc ctgagtggga aatacaccac cgatgactgg gttttcaacc tgatcagcgc
    33601 ctggcagcag cagcattatt cgcgtacctt cccttccggt tcgttaatcg tcaatatgcc
    33661 tcagcgctgg aatcaggatg tgcaggagct gcgcgccgca accctgggcg atgcgcgtac
    33721 cgttgatatg gtgtttgggc tgtaccggca gaacacccgc gagaagttaa attcagccta
    33781 cgacatgccg acaatgcctt atttaagcag taccggctat accaccgctg aaacgctggc
    33841 cgcatacagt gacctgacct ggcatttaac cgatcgtttt gatatcggcg gcggcgtgcg
    33901 cttctcgcat gataaatcca gtacacaata tcacggcagc atgctcggca acccgtttgg
    33961 cgaccagggt aagagcaatg acgatcaggt gctcgggcag ctatccgcag gctatatgct
    34021 gaccgatgac tggagagtgt atacccgtgt agcccaggga tataaacctt ccgggtacaa
    34081 catcgtgcct actgcgggtc ttgatgccaa accgttcgtc gccgagaaat ccatcaacta
    34141 tgaacttggc acccgctacg aaaccgctga cgtcacgctg caagccgcga cgttttatac
    34201 ccacaccaaa gacatgcagc tttactctgg cccggtcggg atgcagacat taagcaatgc
    34261 gggtaaagcc gacgccaccg gcgttgagct tgaagcgaag tggcggtttg cgccaggctg
    34321 gtcatgggat atcaatggca acgtgatccg ttccgaattc accaatgaca gtgagttgta
    34381 tcacggtaac cgggtgccgt tcgtaccacg ttatggcgcg ggaagcagcg tgaacggcgt
    34441 gattgatacg cgctatggcg cactgatgcc ccgactggcg gttaatctgg tcgggccgca
    34501 ttatttcgat ggcgacaacc agttgcggca aggcacctat gccaccctgg acagcagcct
    34561 gggctggcag gcgactgaac ggatgaacat ttccgtctat gtcgataacc tgttcgaccg
    34621 tcgttaccgt acctatggct acatgaacgg cagcagcgcc gtcgcgcagg tcaatatggg
    34681 tcgcaccgtc ggtatcaata cgcgaattga tttcttctga ttattgtaaa agggataccg
    34741 aaaaggtatc ccttttacac cactagttaa aaccagtaac tcagcagagt cgcaaaaaat
    34801 attaatccat agtgattatt taaacaatga aattgcgatt aggacaaata gatttaactt
    34861 tctcgttcct
//
LOCUS       DAPGUL010000041        34336 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.041, whole genome shotgun sequence.
ACCESSION   DAPGUL010000041 DAPGUL010000000
VERSION     DAPGUL010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 34336)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34336)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34336
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.041"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..801)
                     /locus_tag="RHX21_002144"
     CDS             complement(<1..801)
                     /locus_tag="RHX21_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase family protein"
                     /protein_id="HDV1987321.1"
                     /translation="MNPSDAIEAIEKPLSSLPYSLSRHILEHLRKLTRHEPVIGIMGK
                     SGAGKSSLCNALFQGEVTPVSDVHAGTREVRRFRLSGHGHSMVITDLPGVGESRDRDA
                     EYEALYRDILPELDLVLWLIKADDRALSVDEYFWRHILHRGHQQVLFVVTQADKTEPC
                     HEWDMAGIQPSPAQAQNIREKTEAVFRLFRPVHPVVAVSARTGWELDTLVSALMTALP
                     DHAASPLMTRLQDELRTESVRSQAREQFTGAVDRIFDTAESVCIASVAR"
     gene            2032..3516
                     /locus_tag="RHX21_002145"
     CDS             2032..3516
                     /locus_tag="RHX21_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001405821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3987 domain-containing protein"
                     /protein_id="HDV1987322.1"
                     /translation="MSFGQPCDEFPLSSLPPLIRDAVIEAQQITQAPLGLVAASALGA
                     VSLVCQNLIDVCRLNTLRGPVSLFFLTLAESGERKTAVDKLLMKPLYQQEMQLYSRYK
                     SELAVWKNKEELLKAQKKALLSKLNKELRKGADESETLRQLEVLQKNSAEEPVRYKFI
                     FNDATTAAIKNQLCGKWRSVGIMSDEAGIIFDGYTLSELPFINKMWDGSVLSVDRKNE
                     PEQMIENARMTLSLMVQPGLFDRYMERKGSVARDSGFLARCLISKPATTQGKRFINGA
                     VIPGGSLTAFHERLMELARGSIEKSSEDERYCLHFSPEAQKIFIEHYNVLEQDLSPSG
                     PLSPFRGHVSKKTENIARIAALFQYFSYGEGKISADIMTSAVVISSWYTDEYKKLFAL
                     PDESELQQKDAEELFDWLIEECRGECPPRVRKNYILQCGPGRFRNRKKLNALLNILES
                     QFRLSVVPEGKTMYVLLPQIASLKLSDVSGIFTSGYHYNKLRAK"
     gene            complement(3838..4440)
                     /locus_tag="RHX21_002146"
     CDS             complement(3838..4440)
                     /locus_tag="RHX21_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001590672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987323.1"
                     /translation="MKPQYQTRYELLHESYQKWLTGFTRHAVSWGVCHPNIYYFHNLT
                     PGWVSFNGEKPEIAIVPQSLHRLIYGPDKRTTPPLDDDLIVNLCTSEHLLVHHPMLEG
                     ILLSECERLRQRSLANKLISLFRQFGGTELRLKLVWLCWLDLMTGNCLDDWTENLKRK
                     SEKELEEWIINRQKQSAALTDLMDQYVLLAYRTTVDDKRT"
     gene            complement(4527..4733)
                     /locus_tag="RHX21_002147"
     CDS             complement(4527..4733)
                     /locus_tag="RHX21_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001564245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
                     /protein_id="HDV1987324.1"
                     /translation="MITPVSLMDDQMVDMAFITQLTGLTDKWFYKLIKDGDFPAPIKM
                     GRSSRWLKSEVEAWLQARIAQSRP"
     gene            5492..5641
                     /locus_tag="RHX21_002148"
     CDS             5492..5641
                     /locus_tag="RHX21_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin activation protein"
                     /protein_id="HDV1987325.1"
                     /translation="MEKVISHTRYKLTSAELEAFNSVVDHWLAELTMNKLYDRVPASV
                     WKYVI"
     gene            6461..7030
                     /locus_tag="RHX21_002149"
     CDS             6461..7030
                     /locus_tag="RHX21_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus Gp2 family protein"
                     /protein_id="HDV1987326.1"
                     /translation="MTYKYNPFWQQRIRETVRHALDVHPRLTALRVDLRLPDVPAATD
                     AAVISRFINALKARIDAYQKRKHREGKRVHSSTLHYVWAREFGELKGKKHYHLLLLVN
                     RDTWCRAGDYRAPGSLAGMIKQAWCSALGVDVGCHATLVHFPAWPAVWLERDDDTGFQ
                     QVLERAGYLAKEHTKARGTGERNFGCSRG"
     gene            7197..7598
                     /locus_tag="RHX21_002150"
     CDS             7197..7598
                     /locus_tag="RHX21_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004020115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987327.1"
                     /translation="MYAKSFLALDGNGRLTGARTAQTAPYDRYTCHLCGSALRYHPQY
                     DTERPWFEHTDDGLTKHGHECPYVRPERREVRLIKRLQQFVPDALPVVRKASWHCRQC
                     HHDYYGEQYCTNCQTGGFSIPRTTQEEICEF"
     gene            7586..8020
                     /locus_tag="RHX21_002151"
     CDS             7586..8020
                     /locus_tag="RHX21_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001556209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HDV1987328.1"
                     /translation="MRILNCYMANDSKGHFVTAKEAAKHNRRDVLCCVSCGCPLTLQR
                     GNDGQQPWFEHDQMTVAEKILLRCTWLDPAEKEARRLHLQGMTVLDYTVKVRKWFCVM
                     CDEDYEGEKCCPRCGTGVYSRAWGRQEVPSEDARADNPLQRL"
     gene            8789..9015
                     /locus_tag="RHX21_002152"
                     /pseudo
     CDS             8789..9015
                     /locus_tag="RHX21_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229544.1"
                     /note="with IlvB catalyzes the formation of 2-acetolactate
                     from pyruvate, the small subunit is required for full
                     activity and valine sensitivity; E.coli produces 3
                     isoenzymes of acetolactate synthase which differ in
                     specificity to substrates, valine sensitivity and affinity
                     for cofactors; also known as acetolactate synthase small
                     subunit; frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
     gene            complement(9017..9799)
                     /locus_tag="RHX21_002153"
     CDS             complement(9017..9799)
                     /locus_tag="RHX21_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HDV1987329.1"
                     /translation="METKQKERIRRLIEILKKTDRIHLKDAARMLEVSVMTIRRDLHQ
                     EDEPLPLTLLGGYIVMVHKPAPSMPVIQDVPRNHRDDLPIAILAAGMVNENDLIFFDN
                     GQEIPLVISMIPDAITFTGICYSHRVFVALNEKPNVTAILCGGTYRARSDAFYDASNS
                     SPLDSLNPRKIFISASGVHDHFGVSWFNPEDLATKRKAMARGLRKILLARHALFDEVA
                     SASLAPLSAFDVLISERPLPADYVTHCRNASVKIITPDSEDE"
     gene            10102..11022
                     /gene="rbsK"
                     /locus_tag="RHX21_002154"
     CDS             10102..11022
                     /gene="rbsK"
                     /locus_tag="RHX21_002154"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HDV1987330.1"
                     /translation="MDIAVIGSNMVDLITYTNQMPKEGETLEAPAFKIGCGGKGANQA
                     VAAAKLNSKVLMLTKVGDDIFADNTIRNLESWGINTTYVEKVPCTSSGVAPIFVNANS
                     SNSILIIKGANKFLSPEDIDRAAEDLKKCKLIVLQLEVQLETVYHAIEFGKKNGIEVL
                     LNPAPALRELDMSYACKCDFFIPNETELEILTGMSVDTYDHIRLAARSLVDKGLNNII
                     VTMSEKGALWMTRDQEVHVPAFKVNAVDTSGAGDAFIGCFSHYYVQSGDVEAALKKAA
                     LFAAFSVTGKGTQSSYPSIEQFNEFLTLNE"
     gene            11050..12366
                     /gene="fucP"
                     /locus_tag="RHX21_002155"
     CDS             11050..12366
                     /gene="fucP"
                     /locus_tag="RHX21_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose:H+ symporter permease"
                     /protein_id="HDV1987331.1"
                     /translation="MNDKNIIQMPDGYLNKTPLFQFILLSCLFPLWGCAAALNDILIT
                     QFKSVFSLSNFASALVQSAFYGGYFLIAIPASLVIKKTSYKVAILIGLTLYIGGCTLF
                     FPASHMATYTMFLAAIFAIAIGLSFLETAANTYSSMIGPKAYATLRLNISQTFYPIGA
                     ASGILLGKYLVFSEGESLEKQMSGMNAEQIHNFKVLMLENTLEPYKYMIMILVVVMVL
                     FLLTRFPTCKVAQTSHHKRPSAMDTLRYLARNPRFRRGIVAQFLYVGMQVAVWSFTIR
                     LALELGDINERDASNFMVYSFACFFIGKFIANILMTRFNPEKVLILYSVIGALFLAYV
                     ALAPSFSAVYVAVLVSVLFGPCWATIYAGTLDTVDNEHTEMAGAVIVMAIVGAAVVPA
                     IQGYIADMFHSLQLSFLVSMLCFVYVGVYFWRESKVRTALAEVTAS"
     gene            12378..13391
                     /locus_tag="RHX21_002156"
     CDS             12378..13391
                     /locus_tag="RHX21_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HDV1987332.1"
                     /translation="MSTRINLWRALFGEKPRILLENSDFTVTSFRYDSGVEGLKIANS
                     RGHLIILPWMGQMIWDAQFDGHGLTMCNMFRQPKPATEVIETYGCFAFHSGLLANGCP
                     SAEDTHLLHGEMACAAMDEAWLELDGDMLRLNGRYEYVMGFGHHYLAQPTVVLHKSST
                     LFDIKMAVTNLASVDMPLQYMCHMNYAYIPNATFSQNIPDEILRLRESVPSHVNPTAQ
                     WLAFNQRIMQGEASLSTLSQPEFYDPEIVFFADKLDAYTDQPEFRMISPDGTTFVTRF
                     YSAELNYVTRWILYNGEQQVAAFALPATCRPEGYLAAQRNGTLIQVAPQQTRTFTVTT
                     GIE"
     gene            13813..14097
                     /locus_tag="RHX21_002157"
     CDS             13813..14097
                     /locus_tag="RHX21_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001751479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDV1987333.1"
                     /translation="MEQKTLSVEPRRSFSNEFKLQMVKLALQPRGSVARIAREHDIND
                     NLLFKWLRLSLIKGRISRRLPVTNSSGIGVELLPVEMTLDERPYPVFYAR"
     gene            complement(14313..15569)
                     /locus_tag="RHX21_002158"
     CDS             complement(14313..15569)
                     /locus_tag="RHX21_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011815933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDV1987334.1"
                     /translation="MDFFRFLMSDVLSEPAVLVGLIALIGLIAQKKPVTECIKGTVKT
                     IMGFVILGAGAGLVVSSLGDFANIFQHAFGIQGVVPNNEAIVSVAQKSFGKEMAMIMF
                     FAMVINIMIARFTPWKFIFLTGHHTLFMSMMVAVILATAGMTGITLIAVGSLVVGVAM
                     VFFPAIAHPYMKKVTGSDDVAIGHFSTLSYVLAGFIGSKFGNKEHSTEDMNVPKSLLF
                     LRDTPVAISFTMSIIFLVTCLFAGADAVKELSGGKNWFMFSIMQSITFAAGVYIILQG
                     VRMVIAEIVPAFKGISDKLVPNARPALDCPVVFPYAPNAVLVGFLSSFAAGLIGMFTL
                     YLLNMIVIIPGVVPHFFVGAAAGVFGNATGGRRGAILGAFAQGLLITFLPVFLLPVLG
                     DIGFANTTFSDADFGALGILLGIIVR"
     gene            complement(15582..15869)
                     /locus_tag="RHX21_002159"
     CDS             complement(15582..15869)
                     /locus_tag="RHX21_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004717867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDV1987335.1"
                     /translation="MKITVVCGNGLGTSLMMEMSIKSILKDLSVSADVDHVDLGSAKG
                     TPSDIYVGTKDIAEQLAAQSVAGKIVALENMIDKKAMRERLSVVLTELGAL"
     gene            complement(15885..16328)
                     /locus_tag="RHX21_002160"
     CDS             complement(15885..16328)
                     /locus_tag="RHX21_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001497294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDV1987336.1"
                     /translation="MLKNLLNTEVVQVVEQVKDWREAVAISCRPLIENGSIEPRYVDA
                     IYHSHDTIGPYYVVGPGIAMPHARPEEGANKLSLALTLIPSGVNFDADENDPVKLLIV
                     LAATDSTSHIEAISQLAKLFDNEKDIQAILTAKTTQDILSVIARY"
     gene            16599..17630
                     /locus_tag="RHX21_002161"
     CDS             16599..17630
                     /locus_tag="RHX21_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDV1987337.1"
                     /translation="MEKTRKRRGTGRVTLQEVANFAGVGTMTVSRALRTPEQVSDKLR
                     EKIEQAVEELGYIPNRTAGALASGHSHTVAVLVPSLTDKASSRFMQSLQQVLNKNEFQ
                     LLLGCHEYNQLKETEILMTLLQGNPAALVIFGSQLADKTHQILEKTNIPTINVVGSPF
                     SPAQITIETAFFEASYKLTEHLLEQGYKNIGFIGAHMDNRLQRQQLNGWHKAMLSHYQ
                     NSDLVITMPDAPSLQLGRYALNEILLRQPELDAVICSHEEIALGIMFECQRRLLKIPG
                     NIAVACLDGSDNCDQTHPTLTSIRIDYKKMGIETGKLLIGLLNNNHDESEESRIVQFN
                     YQIELRQST"
     gene            18385..19008
                     /locus_tag="RHX21_002162"
     CDS             18385..19008
                     /locus_tag="RHX21_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDV1987338.1"
                     /translation="MRTRIDYLANKYSFTELNESPRLRRQWQDVLEECRQTEAGPEER
                     LRIALLNVDYVTSFELPFRLLLTRTPQLIAALREEWGLSQKNVVFNDKRFGCVYSLKA
                     SLSGVPDTFRYHLSHRIRRMVGNENTSSPYQQIAREVKAPRERLKHALEAGLLVTALD
                     GLFWFGSQRIAADVLRLRKSGMPVVTTTAEVHDNLTGTTRKVPAYHL"
     gene            19097..19312
                     /locus_tag="RHX21_002163"
     CDS             19097..19312
                     /locus_tag="RHX21_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987339.1"
                     /translation="MARSDYDIINLSPEHELNEWLAERGYAGQADNRNRVAEIVTRKL
                     QDSFYMNVSWDALNTACKDVCFPFSPP"
     gene            19454..21220
                     /locus_tag="RHX21_002164"
     CDS             19454..21220
                     /locus_tag="RHX21_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020231833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ShlB/FhaC/HecB family hemolysin
                     secretion/activation protein"
                     /protein_id="HDV1987340.1"
                     /translation="MRHRQDNLLANRTLLPGMVSGQCAFKLRTFSPVARYFSLLPCLC
                     ILSFSSPAAMLSPGDRSAIQQQQQQLLDENQRQRDALERSAPLTITPSPETSAGTEGP
                     CFTVSRIVVSGATRLTSAETDRLVAPWVNQCLNITGLTAVTDAVTDGYIRRGYITSRA
                     FLTEQDLSGGVLHITVMEGRLQQIRAEGADLPARTLKMVFPGMEGKVLNLRDIEQGME
                     QINRLRTEPVQIEISPGDREGWSVVTLTALPEWPVTGSVGIDNSGQKNTGTGQLNGVL
                     SFNNPLGLADNWFVSVGRSSDFSVSHDARNFAAGVSLPYGYTLVDYTYSWSDYLSTID
                     NRGWRWRSTGDLQTHRLGLSHVLFRNGDMKTALTGGLQHRIIHNYLDDVLLQGSSRKL
                     TSFSVGLNHTHKFLGGVGTLNPVFTRGMPWFGAESDHGKRGDLPVNQFRKWSVSASFQ
                     RPVTDRVWWLTSAYAQWSPDRLHGVEQLSLGGESSVRGFKEQYISGNNGGYLRNELSW
                     SLFSLPYVGTVRAVAALDGGWLHSDRDDPYSSGTLWGGAAGLSTTSDYVSGSFTAGLP
                     LVYPDWLAPDHLTVYWRVAVAF"
     gene            21233..31222
                     /gene="cdiA"
                     /locus_tag="RHX21_002165"
     CDS             21233..31222
                     /gene="cdiA"
                     /locus_tag="RHX21_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="contact-dependent inhibition effector tRNA
                     nuclease"
                     /protein_id="HDV1987341.1"
                     /translation="MNQPPVHFTYRLLSYLVSAIIAGQPLLPAVGAVITPQNGAGMDK
                     AANGVPVVNIATPNGAGISHNRFTDYNVGKEGLILNNATGKLNPTQLGGLIQNNPNLK
                     AGGEAKGIINEVTGGNRSLLQGYTEVAGKAANVMVANPYGITCDGCGFINTPHATLTT
                     GRPVMNADGSLQALEVTEGSITINGAGLDGTRSDAVSIIARATEVNAALHAKDLTVTA
                     GANRITADGRVSALKGEGDVPKVAVDTGALGGMYARRIHLTSTESGVGVNLGNLYARD
                     GDITLDASGRLTVNNSLATGAVTAKGQGVTLTGDHKAGGNLSVSSRSDIVLSNGTLNS
                     DKDLSLTAGGRITQQNEKLTAGRDVTLAAKNITQDTASQINAARDIVTVASDTLTTQG
                     QITAGRNLTASATTLTQDGILLAKGHAGLDAGTLNNSGAVQGASLTLGSTTLSNSGSL
                     LSGGPLTVNTRDFTQSGRTGAKGKVDITASGKLTSTGSLVSDDVLVLKAQDVTQNGVL
                     SGGKGLTVSAQALSSGKKSVTHSDAAMTLNVTTVALDGENSAGDTLLVQADKLSTAAG
                     AQLQSGKNLSINARDARLAGTQAAQQTMAVNASEKLTHSGKSSAPSLSLSAPELTSSG
                     VLVGSALNTQSQTLTNSGLLQGEASLTVNTQRLDNQQNGTLYSAADLTLDIPDIRNSG
                     LITSDNGLTLNTASLSNPGKIIADTLNVRATTLDGDGLLQGAGALALAGDTLSQGRNG
                     RWLTAGDLSLRGKTLHTAGTTQGQNLTVQADNWANSGSVLATGNLTASATGQLTSTGD
                     IMSQGDTTLNAATTDNRGSLLSAGTLSLDGNSLDNRGTVQGDHVTIRQNSVTNSGTFT
                     GIAALTLAARMASPQPALMNNGGSLLTSGDLTITAGSITSSGHWQGKRVLITADSLAN
                     SGAIQAADSLTARLTGELVSTAGSKVTSNGEMALSALNLSNSGQWIAKNLTLKANSLT
                     SAGDITGVDTLTLTVNQTLNNQANGKLLSAGVLTLKADSVTNDGQLQGNVTTITAGQL
                     TNGGHLQGETLTLAASGGVNNRSGGVLMSRNALNVSTATLSNQGTIQGGGGVSLNATD
                     RLQNDGKILSGSNLTLTAQVLANTGSGLVQAATLLLDVVNTVNGGRVLATGSADVKGT
                     TLNNTGTLQGTDLLVNYHTFSNSGTLLGTSGLGVKGSSLLQNGTGRLYSAGNLLLDAQ
                     DFSGQGQVVATGDVTLKLIAALTNHGTLAAGKTLSVTSQNAITNGGVMQGDAMVLGAG
                     EAFTNNGTLTAGKGNSVFSAQRLFLNAPGSLQGGGDVSLNSRSDITISGFTGTAGSLT
                     MNVAGTLLNSALIYAGNNLKLFTDRLHNQHGDILAGNSLWVQKDASGGANTEIINTSG
                     NIETHQGDIVVRTGHLLNQREGFSATTTTRTNPSSIQGMGNALVDIPLSLLPDGSYGY
                     FTREVENQHGTPCNGHGACNITMDTLYYYAPFADSATQRFLSSQNITTVTGADNPAGR
                     IASGRNLSAEAERLENRASFILANGDIALSGRELSNQSWQTGTENEYLVYRYDPKTFY
                     GSYATGSLDKLPLLSPEFENNTIRFSLDGREKDYTPGKTYYSVIQAGGDVKTRFTSSI
                     NNGTTTAHAGSVSPVVSAPVLNTLSQQTGGDSLTQTALQQYEPVVVGSPQWHDELAGA
                     LKNIAGGSPLTGQTGISDDWPLPSGNNGYLVPSTDPDSPYLITVNPKLDGLGQVDSHL
                     FAGLYELPGAKPGQAPRETAPSYTDEKQFLGSSYFLDRLGLKPEKDYRFLGDAVFDTR
                     YVSNAVLSRTGSRYINGLGSDTEQMRYLMDNAARQQKGLGLEFGVALTAEQIAQLDGS
                     ILWWESVTINGQTVMVPKLYLSPEDITLHNGSVISGNNVQLAGGNITNSGGSINAQNG
                     LSLDSTGYIDNLNAGLISAGGSLDLSAIGDISNISSVISGKTVQLESVSGNISNITRR
                     QQWNAGSDSRYGGVHLSGTDTGPVATIKGTDSLSLDAGKNIDITGATVSSGGTLGMSA
                     GNDINIAANLISGSKSQSGFWHTDDNSASSTTSQGSSISAGGNLAMAAGHNLDVTASS
                     VSAGHSALLSAGNDLSLNAVRESKNSRNGRSESHESHAAVSTVTAGDNLLLVAGRDVA
                     SQAAGVAAENNVVIRGGRDVNLVAESAGAGDSYTSKKKKEINETVRQQGTEIASGGDT
                     TVNAGRDITAVASSVTATGNISVNAGRDVALTTATESDYHYLETKKKSGGFLSKKTTH
                     TISKDSASREAGSLLSGNRVTVNAGDNLTVEGSDVVADQDVSLAAGNHVDVLAATSTD
                     TSWRFKETKKSGLMGTGGIGFTIGSSKTTHDRREAGTTQSQSASTIGSTAGNVSITAG
                     KQAHISGSDVIANRDISITGDSVVVDPGHDRRTVDEKFEQKKSGLTVALSGTVGSAIN
                     NAVTSAQETKESSDSRLKVLQATKTALSGVQAGQAAAMATATGDPNATGVSLSLTTQK
                     SKSQQHSESDTVSGSTLNAGNNLSVVATGKNRGDNRGDIVIAGSQLKAGGNTSLDAAN
                     DVLLSGAANTQKTTGRNSSSGGGVGVSIGAGGNGAGISVFASVNAAKGSEKGNGTEWT
                     ETTIDSGKTVTINSGRDTVLNGAQVNGNRIIADVGHDLLISSQQDTSKYDSKQTSVAA
                     GGSFTFGSMTGSGYIAASRDKMKSRFDSVAEQTGMFAGDGGFDITVGRHTQLDGAVIA
                     STATPDKNHLDTGTLGFSDLHNEADYKVSHSGISLSGGGSFGDKFQGNMPGGMISAGG
                     HSGHAEGTTQAAVAEGTITIRDRDNQKQNLANLSRDPVHANDSISPIFDKEKEQRRLQ
                     TVGLISDIGSQVADIARTQGELNALKAAQDKYGPVPADATEEQRQAYLAKLRDTPEYK
                     KEQEKYGTGSEIQRGIQAATAALQGLAGGNLAGALAGASAPELAHLLKSTEKDPAVNA
                     IAHAILGGAVAAMQGNNVAAGAAGAATGELAARAIAGMLYPGVKQSDLSEEQKQTIST
                     LATVSAGLAGGLTGNSTASAAVGAQSGKNAVENNYLSEEQSLTFDKELSECRNSGRDC
                     QNVIDKWKKISDEQSAEIDQKLKDNPLEAQVIDKEVAKGGYDMAQRPGWLGNIGVEVM
                     TSDEAKAYVQQWNGRDLTKIDVNSPEWTKFAVFASDPENQAMLVSGGLLVKDITKAAI
                     SFMSRNTATATVNASEVGMQWGQGNMKQGMPWEDYVGKSLPADARLPKNFKTFDYYDG
                     ATKTATSVKSMDTQTMAKLANPNQVYSSIKGNIDAAAKFKEYALSGRELTSSMISNRE
                     IQLAIPADTTKTQWAEINRAIEYGKSQGVKVTVTQVK"
     gene            31222..31725
                     /locus_tag="RHX21_002166"
     CDS             31222..31725
                     /locus_tag="RHX21_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CdiI family contact-dependent growth inhibition
                     immunity protein"
                     /protein_id="HDV1987342.1"
                     /translation="MAFNKDQDYWANIFVTPDFLSVETYSGLGMTGRDPLFSPRLLQP
                     DVDDKSLGEEILQALSDSRTLDVLEDRVAFFDLEKSKEQYAAWIATLMEKYGYRTKRA
                     LFKNMKKVGIHLVNDVITIRPSFHEKLEAWSGNRINESDYVVLPADSSPTEIGSGLRL
                     ALSRCKG"
     gene            32208..33421
                     /locus_tag="RHX21_002167"
     CDS             join(32208..32499,32499..33421)
                     /locus_tag="RHX21_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558238.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDV1987343.1"
                     /translation="MTKNTRFSPEVRQRAIRMVLESQDEYDSQWAAICSIAPKIGCTP
                     ETLRVWVRQHERDTGGGDGGLTTAERQRLKELERENRELRRSNDILRQASAYFGEGGV
                     RPPLEKMMPLLDKLREQYGVGPVCSELHIAPSTYYHCQQQRHHPDKRSARAQRDDWLK
                     KEIQRVYDENHQVYGVRKVWRQLLREGIRVARCTVARLMAVMGLAGVLRGKKVRTTVS
                     QKAVAAGDHVNRQFVAERPDQLWVADFTWVSTWQGFVYVAFIIDVFAGYIVGWRVSSS
                     METAFVLDALEQALWARRPSGTIHHSDKGSQYVSLTYTQRLKEAGLLASTGSTGDSYD
                     NAMAESINGLYKAEVIHRKRWKNRTEVELSTLTWVDWYNNRRLLERLGHIPPAEAEKA
                     YYASIGNDDLAA"
     misc_feature    32489..32605
                     /locus_tag="RHX21_002167"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01497"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="AL1L pseudoknot; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /db_xref="RFAM:RF01497"
     gene            complement(33464..33676)
                     /locus_tag="RHX21_002168"
                     /pseudo
     CDS             complement(33464..33676)
                     /locus_tag="RHX21_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001311740.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase family
                     protein"
     gene            33730..34155
                     /locus_tag="RHX21_002169"
     CDS             33730..34155
                     /locus_tag="RHX21_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001373091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HDV1987344.1"
                     /translation="MELQDWRKEPRKNYSNEFKLRMVELASQPGACVAQIARENGVND
                     NVIFKWLRLWQNEGRVSRRLPVTTSSDTGVELLPVEITPDEQKEPVAAIAPSLSTSTQ
                     TRVSASSCKVEFRHGNMTLENPSPELLTVLIRELTGRGR"
     gene            34152..>34336
                     /gene="tnpB"
                     /locus_tag="RHX21_002170"
     CDS             34152..>34336
                     /gene="tnpB"
                     /locus_tag="RHX21_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017901265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HDV1987345.1"
                     /translation="MISLPSGTRIWLVAGVTDMRKSFNGLGEQVQHVLNDNPFSGHLF
                     IFRGRRGDTVKILWADA"
BASE COUNT         8845 a         8098 c         9171 g         8222 t
ORIGIN      
        1 gcgtgcaaca gaggcaatac agacgctctc cgccgtgtca aatatccggt ccaccgcacc
       61 ggtaaactgt tcacgggcct gagaccggac agattccgtg cgcagctcgt cctgcaggcg
      121 ggtcatcagg ggactggcgg catggtcggg aagcgctgtc atgagcgcac tgaccagcgt
      181 atccagttcc cagccggtgc gggccgatac ggccacaacc ggatgtacgg gccggaacag
      241 acggaatacc gcctccgttt tttcgcgaat attctgtgcc tgtgcgggag aaggctgaat
      301 accggccata tcccattcat ggcagggctc cgttttgtcg gcctgcgtca ccacaaacag
      361 cacctgctga tgtccccggt gcaggatgtg tcgccagaaa tactcatcca cagacagggc
      421 gcggtcatcg gctttaatca gccacagcac caggtccagt tcgggcagaa tgtcacggta
      481 cagggcttca tactctgcat ccctgtcccg gctctcgccc accccgggca ggtcagtgat
      541 aaccatgctg tgaccgtggc cactcagacg gaagcgccgc acttcccggg tgccggcgtg
      601 aacatcactg accggggtga cctccccctg aaacagtgca ttacagagtg aggatttacc
      661 ggccccgctt ttacccataa tgccaatcac gggttcgtga cgggtgagtt tgcgcagatg
      721 ttccaggatg tgacgggaaa gtgagtaagg cagggaggag agcggttttt caattgcctc
      781 aatggcatca gacggattca tacatgtatt cccggtgaaa aaagacaaaa ccccgcgcac
      841 cggaaaggtg gcgggggatt cacggagata atatctgtct gaaattgttt tgaatcgatg
      901 ggattgttgc gtattaacat gaaggagatc aggacttatc cgttactggg tgatctcctt
      961 ccatgaaaat acgccgttat tgttaaacag caggctgatt tctccgtaaa ggggaaaata
     1021 tttatcggct gtatgattat caggtgtgtc tgtgtttact gctgtgagta ttttttagtg
     1081 tattgtgggg gagatgtcag tgggagatat taaatttacg tttataatta tcttacttct
     1141 tctgtgtgtt ttttataaga gtgcacacgt aatgatatct gttgatacca tgtggttaag
     1201 tgtttccctt cctggtcatg cgtaatgatt aaatgctttt gtgacaccat tcttccggtc
     1261 tgaatattta tcccgttctt ttttatttgt gcagtgatac tgtcggaaga gaattcagta
     1321 atgtgaggtg tcctggtcag gataatatct gctgagatat tattagttga gtgtgttttt
     1381 actgagcaaa agctggcttt taattcctgt actgaaacac tgtcgctcgt ccggggttaa
     1441 ctgaaactgg atgatgatgt aaaatgaagg ctgtttttgt gtttgtcgaa gaagtgttat
     1501 tttaatccat tctcatcatt ggctggcgat tatacagaag tatttgaaga aaaaatggtg
     1561 cattttatct gtgtcagcag ggaagaagta ttttattgat gtatcagtat taaatggttt
     1621 ttgttattta taaaaatgtc atcttgtcca tagaatattg tactcagcat tcagtgcagg
     1681 aactgtagtc ttctttattt tattcttctt caggaggggg ggtgattcct gaaggcgtta
     1741 ttcccggtgt tctgtttatg attcttcccg gcaggaaacc ggtatctgca atacccggga
     1801 tgatgctttt tgttcgtacg tggttgtgta aaatttgaat agtggatgtg ctccgaaggg
     1861 aaggagggga cacacagatt cattttgtct ttcttcagca gcaaaataca ctgtggttat
     1921 tatttaacca ttaaatcaac aaaattttta cctcatattg atttgactgc tatttttgct
     1981 attaatagcc agaattgcag tgcttttata tctgtgtata gtgaggttac tatgtcattc
     2041 ggtcagcctt gtgatgagtt tcccctgagt tcgctgcctc cactcattcg tgatgccgtt
     2101 attgaagctc agcaaattac gcaggctccc cttgggcttg tggcagcgtc tgccctgggc
     2161 gctgtttcac ttgtctgcca gaatctgatt gatgtctgca gactgaatac actgcggggg
     2221 ccggtctctc tttttttcct gacgcttgcc gagtccggag aacgaaaaac cgcagtggac
     2281 aaattattaa tgaagcccct gtaccagcag gagatgcagt tatattccag atacaaaagt
     2341 gaactggctg tctggaaaaa caaggaagag cttttaaagg ctcagaaaaa agcattgttg
     2401 tcaaaactga ataaagaact ccgcaaaggc gcggatgagt cagaaaccct cagacaactg
     2461 gaagtacttc agaaaaacag tgcggaagaa cctgtgaggt ataaattcat ttttaatgat
     2521 gccacgactg cggcaattaa gaatcagctt tgtggtaaat ggcgttcagt gggtattatg
     2581 tcagatgaag ccggtattat atttgatgga tataccctgt ctgagttgcc ttttattaac
     2641 aaaatgtggg atggctctgt attgtctgtg gacagaaaga atgaacccga acagatgatt
     2701 gaaaatgcca gaatgacgtt atccctcatg gtgcaacccg gtctttttga ccgatatatg
     2761 gagcgaaaag gttctgttgc cagggacagt ggttttcttg cccgttgtct tatcagtaaa
     2821 cctgcaacca cgcaggggaa acgctttatt aacggagctg tgattccggg aggatcatta
     2881 acggcatttc atgaacgatt aatggaactg gccagaggca gtattgaaaa atccagtgag
     2941 gatgaacggt attgtctgca tttttcgcct gaagcgcaaa aaatatttat tgagcactat
     3001 aatgttctgg agcaggattt atccccttcc ggacccttaa gcccgtttcg gggacatgtt
     3061 tcaaaaaaaa cagaaaacat tgcaagaatt gcagcgttat ttcagtattt cagctatggt
     3121 gaagggaaaa tctctgccga tatcatgacg tctgctgtcg taataagttc gtggtacaca
     3181 gatgaatata aaaaattatt tgcgttacct gatgaatctg aactgcagca gaaggacgcc
     3241 gaggagctgt tcgactggct cattgaggag tgccgcggag aatgcccgcc ccgtgtcagg
     3301 aaaaattata ttctccagtg tggcccgggc cggttcagaa acaggaaaaa actgaacgca
     3361 ttgctgaaca ttcttgaatc tcagttcagg ctttctgtcg tgccggaagg aaaaaccatg
     3421 tatgttctgc ttccccagat agccagttta aagttgtctg atgtctctgg tatttttacc
     3481 tcgggttatc actacaataa gctgagagcg aagtaaccgg tgagcagttt ttctccatta
     3541 tgcttcagac ttagatgatt gattattatg gggatttcat caccgatatt cagatgtatg
     3601 aatatcggtg atgaactaaa gctcaggagc tgcgtggtgg tgatgaatca acaggcatat
     3661 aactgatacc cgccggtcag aagttccagc ctgcgacttt cctgtctgcg tgcccgcagt
     3721 ccggcgttca ggtgcagcgt gtgacagaac gcacggagag cgaaacggca ggcagacagg
     3781 ccgttcagtc agccctggca ccctgcccgg ataccagctt ccctgaaaca actggcatca
     3841 ggtgcgctta tcgtcaaccg ttgtgcggta tgccaggagc acgtactgat ccatcagatc
     3901 cgtcagtgct gcgctctgct tctgacggtt gatgatccat tcctccagct ctttttctga
     3961 tttccgtttc agattctccg tccagtcgtc aaggcagttt ccggtcatta aatcaagcca
     4021 gcaaagccag accagtttga ggcgcaactc cgtgccacca aactgacgga agaggctgat
     4081 cagtttattt gccagcgaac gctgcctcag acgttcacat tcagacagga gaatgccttc
     4141 cagcatcgga tgatgaacca acagatgttc actggtgcat aaattcacta tcagatcatc
     4201 atccaggggc ggcgtggtcc gtttgtccgg accataaatc agccggtgca gactctgggg
     4261 tacgatggca atctccggtt tttcaccatt gaatgacacc cacccgggcg tcagattatg
     4321 gaagtagtag atattcggat gacacacgcc ccaggatacg gcgtgccggg tgaagccggt
     4381 cagccatttc tggtagcttt cgtggagcag ctcgtaacgg gtctgatact gtggtttcat
     4441 tttcatattc ctcacggggg ataacaggca gcagaacgcc gccggcaggc cggagactgc
     4501 gtctgctgca gatgaacggt taagaattac ggacgggact gtgcaatacg cgcctgcagc
     4561 caggcttcca cttcgctttt cagccatcgg gagctgcggc ccattttgat gggcgcagga
     4621 aagtcaccat ccttgatgag tttgtaaaac cacttatcgg tcaggccggt cagttgagtg
     4681 ataaatgcca tgtcgaccat ctggtcatcc atcagtgaaa ctggggtgat catgagaatg
     4741 ttcctccgga tgttgttaaa ccagccggtg tggtcatgaa aacaacgcac caccttcacc
     4801 ggcataacaa ccggggagaa acgtaaaaaa taatcgggaa tgtgaccgcc aggagataaa
     4861 cggggaggtt acggtggctg agccgtaccg gtatgccggg tggttgttac gaaacgatgc
     4921 ttccgcacgc gtgcgcgata aagaagggat gattttcgtg aggaagaggg gaaaactggc
     4981 gttctgataa ttgcagagtt atttacgggg cggttacgat ggggcagacc gtgtccggtg
     5041 ggcaggcgac aggtatcacc gatgggataa gactgtctga ttggtattat aaatatataa
     5101 gagagatcaa acacatgaga tcaaatacat gagttcatat atgtgaaata aacacggtga
     5161 gtgtgatcag tgggcatgat gagaacgcag tagcaacaga ctgcgctatc cctgatagct
     5221 ggcgtataac ccgcgtatat aaaacgtatc tgcaatgtac gtgaacagag tgcattaagc
     5281 atccgtctga gcggtaaaca tatccgacct ggtgagtgac agtctgagag accggttaag
     5341 tggtggctcg ggagtaatga gtttggggtg ggtaccagaa tgccagtctg gcggtatgct
     5401 gacagtatca cgttaattgc agcataaagt gatgagaggc taatggaagt taaaaccaaa
     5461 gcagttccgt cgttgttcat cccgggagac gctggaaaaa gtgatttccc acacgcgtta
     5521 taaacttacc tctgcggaac tggaagcctt caactctgtg gttgatcact ggctggcaga
     5581 actgacaatg aacaagcttt acgatcgtgt tcccgcttca gtctggaaat atgtcatctg
     5641 agcgttcggt aatcacaact gcatcgcgcc aggtgttatc cgctttgtga ttcttattgg
     5701 ctcttctcag gttattaaaa gctgaatatg ttccttttgt cgggaaccag gataataccg
     5761 ggaacgttaa gcggtatagc gacaacaaag aattcgaaat caaaagggaa tggtgccgga
     5821 ggcgtgggcg gtaatgggct gattttcagg tattaccggc ttacagcgtg tggttgatat
     5881 tgaggggctg tgagtttcac gtatttgtca gaaacccaga cgagttttcc tgtatgggac
     5941 gaaataaggc agcggcaata catggaaaaa tttaatatgg tatgaaggag aacctgtcgg
     6001 ttacgcttaa tataaccggt acactgtcag ctcaggggat acatgaaccg ttatctcacc
     6061 agctacacag tatatacaca ctgacgctga cagtagtcag caggaccaca ataatcagtg
     6121 ccagcagtat ggtaacgata cggtctgtat tccggtaata gccgaagggg tcgacagaac
     6181 cacaatacgg gcaacacaca gtattatgag taatcgcgtt tccacagtcc cagcacttct
     6241 ttttgcgtat caccataact ccctcctcac agccttaccc gtaaccggtt ttttacatta
     6301 aaaaaacaac gctgaaaatt caaccgtcag tccggagacg accgttcggg ttatctcaga
     6361 gtgcctgaga tattgcctgg ttggagatca cttcagggac tctgcgcatt ttttacggcg
     6421 tggttaatcc gtatgaacga aaccatacgg agatttaacc atgacctaca aatacaaccc
     6481 cttctggcag caacgtattc gtgagacggt gcggcacgca ctggatgttc atccccgtct
     6541 gacggcattg cgggttgatc tgcgtctccc ggatgtaccg gcagcaacgg acgcggctgt
     6601 gatatcccgc ttcatcaatg ccctgaaagc ccgaatcgac gcttaccaga aacgtaagca
     6661 tcgggaaggt aaacgcgtgc attcctcgac cctgcattac gtctgggccc gggagttcgg
     6721 ggagcttaaa ggcaaaaaac actatcacct gctgctgctg gtcaaccggg atacctggtg
     6781 tcgtgccggc gattaccgcg ctccggggtc actggccgga atgattaaac aggcgtggtg
     6841 cagtgccctg ggagtggatg tcgggtgcca tgccacgctg gtgcattttc cggcctggcc
     6901 ggcggtgtgg ctggaacgcg atgatgacac tggctttcag caggtgctgg aacgtgctgg
     6961 ctatctggcg aaggagcata ccaaagctcg cggcaccggt gagcgcaact ttggctgcag
     7021 tcgtggctga gcccgacaga cgacttatct gaccttagtg tgatgacgcg ttcacagcga
     7081 ccacactgat tttcccttct gagactgaac tgaaaaccgc tattcacacc tgaccacgct
     7141 gcccgtaccg ggacggctgt tgcctgcgtg tcgtctggcg gctgaggaat atgacgatgt
     7201 acgcaaaatc ctttctcgca cttgatggca acgggcgtct gactggtgcc cgtaccgcac
     7261 agactgcacc ttacgatcgc tacacttgcc acctttgcgg cagtgcactc agataccacc
     7321 cgcaatacga cactgaacgt ccctggtttg aacacactga cgacgggctg actaagcacg
     7381 gtcatgagtg cccttatgtc agaccggaac gcagggaggt acgcttgatt aagcgtctgc
     7441 agcaattcgt accggatgcc ttacccgtgg tgcgtaaagc cagctggcac tgcagacaat
     7501 gtcaccacga ttattatggg gagcagtact gcacaaactg ccagaccgga ggattcagta
     7561 ttccccggac aactcaggag gaaatatgcg aattctgaac tgttatatgg cgaatgacag
     7621 caaggggcat tttgttacgg cgaaagaagc agcgaagcac aaccgccggg acgttttgtg
     7681 ctgtgtgtcc tgtggatgcc cgttaacact tcagcggggc aatgacggac aacaaccgtg
     7741 gtttgaacat gaccagatga ctgtcgctga gaaaatcctg ctgcgatgca cctggcttga
     7801 cccggcagag aaagaggccc gtcgtttgca tctgcagggt atgacggttc tggattatac
     7861 ggtgaaggtg agaaagtggt tttgtgtgat gtgtgacgaa gattatgaag gagaaaagtg
     7921 ctgcccgcgt tgtggtaccg gggtatacag cagggcgtgg gggcggcagg aggtgccgtc
     7981 ggaagatgcc agggctgata atccgttaca gaggttgtaa tggttgcctc tggcgcagtt
     8041 tgcggtgatg ccgttcccgg gaatggattg ccagtgcggg gactgtggag cttaattccg
     8101 gtgttggtgg cctttccgtt gattttatgc caacagcccc cctgtgactg acaggctgcc
     8161 tcgtcattcc attcgtatct ccagtaacag ggggtgtatt ttattgtgcc ggttcaggcg
     8221 tgcgtttccc ggcgcgtctg caccggctta accaaattca acagggataa aatagtgtaa
     8281 ataaccgaag tattacttgc agaatcgggg gaagcatccg gggttttatt caacaggcat
     8341 gggaggctcc ggctctgaca gacattgtac tgtggaatgt tgttacaggt tggggcggca
     8401 accgtgccag gagaccatga gccgttcacg gcattaaagg ccacacttca gtcgtttaca
     8461 ttccctgtgg tggcaggcat cttccgttaa ggcgtcagag cgttaccaac gttatgttgt
     8521 catggctcac ctttcatagt cgatgcttat ctggtgactg aaactagccg cagataaaga
     8581 gtgtgaagtt gataccatgg agtggagtga cgtgcaggca ggagattcgc tctatgcagg
     8641 gttgtgagat gaattcaaac cggctgtcag cgccagtaat atttgaagat tcgtccggtt
     8701 gttatccagt gtgcattaaa aacccagaca ttatggacaa tacaacggct tccataacag
     8761 ggaggagcct gtttattatc cgggcgtaat gactaacctt tgtgggcttt ttcccgtcgt
     8821 gcttttaacg ttgaaggcat tttctgcctg ccgattcagg acagcgacaa aagccatatc
     8881 agactattgg tcaatgatga ccagcgtctg gagtagatga taagccaaat tgataaactg
     8941 gaatatgtga tgaaagtgca acgtaatcag tccaatccga cgatgtttaa caagagtacg
     9001 gtgttttttc agtaagtcat tcgtcttctg aatcaggtgt aatgatcttt acagaagcat
     9061 tccggcagtg cgtaacataa tctgccggta acggacgctc gctaatcaga acatcaaatg
     9121 cagagagcgg tgcgaggctg gcagaggcta cttcatcgaa caaggcgtgg cgggcgagca
     9181 aaattttcct tagtccacgg gccatcgctt tacgcttagt ggcaagatct tcgggattaa
     9241 accagctgac gccaaagtga tcatgtacac cgctggcgga aataaatatt tttcgcggat
     9301 tgagagagtc taatggcgaa gagttactgg catcgtaaaa agcatcactt ctggcacgat
     9361 acgtaccacc acaaagtatt gctgtcacat taggtttttc attcaacgca acaaagacac
     9421 gatgtgagta acagatgcca gtgaaggtga ttgcatccgg gatcatgctt ataacgagcg
     9481 gtatctcctg gccattatca aagaagatca gatcattttc attaaccatt ccggcggcca
     9541 gaattgcaat aggtaagtca tcacgatgat ttctcggaac gtcctggatt actggcatgg
     9601 atggtgcggg tttatgcacc attacaatat agccacccag tagggtcagt ggcagaggtt
     9661 catcttcctg atggagatcg cgacgaatag tcattacaga aacttccagc attcgtgccg
     9721 cgtctttcaa atggattctg tcggttttct taagtatttc aatcaaacgt cggatacgct
     9781 ctttttgctt cgtttccatc aactctctcc gtaaaatgtt ataaaaataa cattatggca
     9841 ttagtaaaca ttgttttagt taccatacta tacgaccgac cctttgaaat gaaaagggta
     9901 tagactgctg aattttcggt attaatcctg ttaggttgct tatgattaga tagtgttggc
     9961 ctgagtgata agactggaag tctattaaat aaacatcgag ttgatgtgct aatcgcgatc
    10021 tcagtcacaa atgatgtaaa agtaacatgc taatgttatt taaataccat tgttatgcga
    10081 aagtttataa gaggtagtga aatggacatt gcagttattg gttccaatat ggtggatctc
    10141 attacttaca ctaatcagat gcctaaagaa ggagaaactc tggaagcacc tgccttcaaa
    10201 atcggatgtg gtgggaaagg tgctaatcaa gcggtggcgg cggctaaatt gaattcaaaa
    10261 gtcctgatgc tgactaaagt aggtgatgat atttttgcgg ataatactat tcgtaatctc
    10321 gaatcatggg gaattaatac cacttatgtt gagaaagtcc cctgtaccag cagtggtgtt
    10381 gcaccgatct ttgttaatgc caactcgagc aatagtatat taataattaa gggagcgaat
    10441 aaatttcttt ccccggaaga tatcgatcga gctgcagaag atctgaaaaa atgcaaattg
    10501 atcgttttac aactggaagt tcaactggaa acagtttacc acgcgattga gtttggtaag
    10561 aaaaatggta ttgaagtgtt attaaatccg gctccggcat tgcgtgagtt agatatgtct
    10621 tatgcctgca aatgtgattt ctttatcccg aatgaaacag aactggaaat attaaccggt
    10681 atgtcggttg atacttatga tcatattcgt ttggccgcac gttcgttagt tgataaaggg
    10741 ctgaacaata ttattgttac catgagcgaa aaaggcgcat tatggatgac ccgcgatcag
    10801 gaagtccatg ttcctgcatt caaagtaaat gctgttgata ctagtggcgc tggtgacgca
    10861 tttattggtt gcttttccca ttattatgtt caaagcggtg atgttgaagc cgctttgaaa
    10921 aaagccgctc tctttgccgc tttcagcgtc acagggaaag gtacgcaatc atcttatccg
    10981 agtattgaac aatttaatga atttttaacc ttaaacgaat aatcatcctg cacagttaaa
    11041 ggtagcacta tgaacgataa aaacatcatt cagatgcctg atgggtatct gaataagact
    11101 cccttgttcc agtttatttt gttatcgtgt ttattcccgc tatggggatg cgcagctgca
    11161 ttaaatgaca tattaatcac tcaattcaaa agtgtatttt cgctaagtaa ctttgcttca
    11221 gcattggtgc agagcgcatt ttatggaggt tattttttaa ttgcaatacc agcatccctt
    11281 gtgattaaaa agaccagtta taaggtggca attttaattg gcctgacgct gtatattggt
    11341 ggttgtacac tttttttccc tgcctcgcat atggcaacct acactatgtt ccttgcagct
    11401 atttttgcga ttgcgattgg cctgagtttc cttgaaactg cagcgaacac atacagttca
    11461 atgatcggtc caaaagccta tgccacattg cggctcaata tcagccagac cttttatccg
    11521 attggtgctg cgtctggtat tttattgggc aaatatctgg ttttctccga gggggaaagc
    11581 cttgaaaagc agatgtcagg aatgaacgcc gagcaaattc acaactttaa ggtgctgatg
    11641 ttagagaaca cccttgaacc gtataagtat atgattatga ttctggttgt ggtcatggtg
    11701 ttgttccttt taacccgctt cccaacctgt aaagtggcac agacaagtca ccataaacgc
    11761 ccgtcagcaa tggatacgct gcgctatctg gctagaaatc cgcgctttcg tcgcggtatt
    11821 gtggcgcagt tcctttatgt gggtatgcag gtcgcagtat ggtcatttac catccgtctg
    11881 gcgctggagt tgggcgatat caacgaacgt gatgcttcaa acttcatggt ctatagcttt
    11941 gcctgcttct ttattggcaa gtttatagcc aatatcctta tgacgcgttt taatccggaa
    12001 aaagtattga ttctctattc cgttataggg gcgctgttcc tggcatatgt tgcactggct
    12061 ccaagtttca gcgcggtcta tgtcgccgtc ctggtaagtg ttttgtttgg cccttgctgg
    12121 gcgacgatct atgcaggaac actggataca gttgataacg aacatacaga aatggcagga
    12181 gcagtcattg ttatggctat tgtcggtgcc gcggtggttc cggcaattca gggatatatt
    12241 gcagatatgt tccactcact acagctttca ttcctggttt ctatgctctg ctttgtctat
    12301 gtcggagtct acttctggcg tgaaagcaaa gtacgtaccg cactggctga agtcacagcg
    12361 tcctgaggag aaccgttatg agtacgcgta ttaatttgtg gcgggcgctt tttggcgaga
    12421 aacctcgtat cttgctggaa aatagtgatt ttactgtcac gtcttttcga tatgacagcg
    12481 gtgtcgaggg gcttaaaatt gcaaacagtc gtggacattt gattattctt ccctggatgg
    12541 ggcagatgat ttgggatgcg caatttgatg gacacggcct caccatgtgc aatatgtttc
    12601 gccagcctaa accggcgaca gaggtgatag agacctatgg ctgttttgct tttcattcag
    12661 gtttgctggc taatggctgc ccatctgcgg aagatactca tctgctacac ggtgaaatgg
    12721 cctgtgccgc gatggatgaa gcatggctgg aattagacgg agatatgtta cgccttaacg
    12781 ggcgttacga gtatgtaatg ggtttcggtc atcattatct ggctcagcca acagtggtcc
    12841 ttcacaaatc ctctacactg ttcgatatta agatggccgt aaccaatctg gcttctgtag
    12901 atatgccact acaatatatg tgccacatga attatgcata tataccaaat gctacattca
    12961 gccagaatat cccggacgaa atattaagat tgcgtgaatc agtgccttcg catgttaatc
    13021 ccaccgctca gtggctggcg tttaatcaac ggattatgca gggagaagcc tctctgtcga
    13081 cgctgagtca accggaattt tatgatccag aaattgtctt ctttgcagac aaactggacg
    13141 cttatacaga tcagccagag tttcgcatga tctctcccga tggcactacg tttgttactc
    13201 gtttctacag tgctgaacta aattatgtga cacgctggat cctttataac ggagagcaac
    13261 aggtagccgc ctttgcatta cctgcaacct gtcggcctga ggggtatctt gccgcgcaac
    13321 gtaatggcac gctgattcag gttgcaccgc agcaaacgcg cacttttaca gtcaccacag
    13381 gaattgaata accactcaag gcctgaacag cggcgcgctt atcgttaagg taagcgcgtt
    13441 tttttacccg ccaggacaag actatgatag cgttgccctt atagacgatc acattatcgt
    13501 ccactccaaa tttgcgcaac tactgtagag tggtgtgctc cacagcttct ttgaggagct
    13561 taacctccat tgttttctta ccgagcaagc actgcaactc ttttatttat ttgtagtggt
    13621 caacaaaaac tggtcacaat ttcagttttt ttccagtatc tattttccga ttcgttcggc
    13681 ggtaatccac cgttatattc atgaggccgg agtgcactat aaaagtgtat gcgtaaaccg
    13741 actgctgtat gtagccatta agccagtatt ggtaacatag gtacccacct tttcaactag
    13801 tggacacctg ttatggaaca aaaaacatta tcagttgaac cccgcaggtc attttcaaat
    13861 gagtttaaac ttcaaatggt taaactggct ttacaaccaa ggggttctgt tgcccgtatt
    13921 gcccgggagc atgatatcaa tgataatctt ctgttcaaat ggctcaggct ctcgctgatc
    13981 aaagggcgta tatcacggcg tcttccggta acgaactctt ctggcattgg cgttgaatta
    14041 ttacctgtgg agatgacgct ggatgagcgg ccttaccccg ttttttacgc gaggtaatta
    14101 tgaagatcaa tgactagccg tcgaaccgtg tgcatgaact gctgcactga aacttctcag
    14161 ctgtaaaata atccttacgc tacgtacttc tcggagcgct tacgattaat cggatgcagt
    14221 cctgactgga agaaagaaaa atggagaaaa taagaggaat taatatcctc cacgttcctg
    14281 aaatcctgga ggatattaat gtcatcaaaa tattagcgaa cgataatccc taacaaaata
    14341 cccagtgcgc caaagtcagc atcactgaag gtggtgttag caaaaccaat atcacccagc
    14401 accggcaata agaatactgg caggaaggta ataagcaagc cctgagcgaa ggcacccaaa
    14461 atcgcaccac gacgtccacc cgttgcatta ccgaataccc ctgcagctgc acctacgaag
    14521 aagtgcggca ccacaccagg aataatcacg atcatgttca gcagatacaa cgtgaacata
    14581 ccgattaaac ctgcagcaaa gctactcagg aaaccaacca gtacagcgtt aggtgcgtaa
    14641 gggaagacga ctgggcaatc gagagcaggt ctggcattcg gaaccagctt gtctgaaata
    14701 cctttgaatg ccgggacaat ctccgcaatc accatgcgca caccctgcag aatgatgtac
    14761 acgccagctg cgaaggtaat ggattgcatg atagagaaca tgaaccagtt tttaccaccg
    14821 ctaagctctt tcaccgcatc tgcacccgca aacaggcacg tcaccaggaa aattatgctc
    14881 atggtaaaag agatagcaac cggcgtgtcg cgcaagaaca gcagactttt cggcacattc
    14941 atgtcttcag tcgagtgctc tttattacca aacttgctgc cgatgaaacc ggccaataca
    15001 taagataatg ttgagaagtg gccgatggca acgtcatcag aaccggtcac tttcttcatg
    15061 tacggatgcg caatagccgg gaaaaagacc attgccacgc caacaaccaa agagccaacg
    15121 gctataagcg taatgccggt catgcctgct gttgccagaa ttaccgctac catcatcgac
    15181 ataaacaacg tgtgatgacc ggtcaggaag ataaatttcc acggtgtgaa acgggcaatc
    15241 ataatgttga taaccatcgc aaagaacata atcatcgcca tttctttccc gaagcttttc
    15301 tgcgctacgg aaacaatggc ttcattgttc ggcactacac cctgaatacc aaaggcatgc
    15361 tggaaaatgt ttgcgaagtc acccagtgac gacacaacta aacccgcccc tgcgcctaaa
    15421 atcacaaacc ccataatggt cttgacggta cctttaatgc attcggttac cggttttttc
    15481 tgtgcaatca ggccaatcag ggcgattaaa ccgaccagca ctgcgggttc ggaaagtaca
    15541 tcgctcatca aaaaacgaaa gaaatccata tcgcccccag cttacagtgc gcctaattcg
    15601 gttaatacca cggacaaacg ttctctcatg gctttcttat caatcatatt ttccagtgcg
    15661 acgattttgc ctgcgacaga ctgcgcggct aactgctcgg caatgtcttt ggtgccgaca
    15721 tagatatcac tcggcgtccc tttcgcggag cccaggtcga cgtgatcaac atcagcgctg
    15781 acggacaaat ccttcaaaat gcttttaatg ctcatttcca tcatcaggct ggtgcctaag
    15841 ccgttaccgc aaaccactgt aattttcata aatgttcctc tggattaata gcgcgcaata
    15901 acagacaaaa tgtcctgcgt cgttttggcc gtcaaaatgg cctgtatgtc tttttcgtta
    15961 tcgaataact tggcgagttg agaaatcgct tcaatgtggc tggtactgtc ggttgcagcc
    16021 agcacaatca gtaatttcac tggatcgttt tcatcggcat caaaattcac acctgaaggg
    16081 atcagggtca gtgctaatga cagcttgtta gccccctctt ccgggcgcgc atgaggcatc
    16141 gcaataccag ggccaaccac atagtacgga ccgatagtgt cgtgcgagtg atagatcgca
    16201 tcaacataac gcggttcgat agagccgttt tcaatcaacg gtcggcatga aatcgccacg
    16261 gcttcccgcc agtctttgac ctgttccacg acctgaacga cctctgtatt taatagattt
    16321 tttaacatgc tactgataac tcccgatgat aattaacagg agagtagata ttttacgcat
    16381 taattaatgt gatgattgtc gcatttgata gcgctatctg ataacgctac caatctttgt
    16441 gatagcgcta tcatttctct gccgccatgc tttggctata ttcggttcct gcatatacaa
    16501 tgcaacagga tatttgctac cgtgggcaaa aactggaaag agtaatggta aaataaaagt
    16561 aatgaaaaca gctggttgta attatccatg gagtcgaaat ggaaaaaaca cgtaagcgcc
    16621 gtggtaccgg acgggtgacg ctgcaggagg tcgctaactt tgcaggtgtc ggaaccatga
    16681 ccgtttcccg cgcgctgaga acaccggaac aggtttctga caagctgagg gaaaagatag
    16741 aacaggccgt agaagagttg ggttatattc ccaacagaac tgctggcgcc cttgcatctg
    16801 gtcacagtca tacagtcgcc gtactggttc cttccctgac agataaagcc agctcccgct
    16861 ttatgcagtc gttgcaacag gtgcttaata aaaatgaatt ccagctactg cttgggtgtc
    16921 atgagtataa tcagctcaaa gaaactgaaa ttctgatgac gcttcttcaa ggcaacccgg
    16981 cggcgttagt tatttttggt tctcagttgg ctgataaaac tcaccagata cttgagaaaa
    17041 caaatatacc taccattaac gttgtcggtt cccctttcag tccggctcaa attaccatcg
    17101 aaacagcatt ttttgaagca tcatataaac tgaccgaaca tctgctggaa cagggttata
    17161 agaatatcgg atttatcggt gcgcatatgg acaaccgcct gcaacgtcag caactgaacg
    17221 gttggcataa agcaatgttg agccattacc agaactctga tcttgttatc accatgccgg
    17281 atgccccaag tctgcaattg gggcgttacg cattaaacga gatattactg cgacaaccag
    17341 agctggatgc tgtgatttgc agccacgaag agattgcgct gggtatcatg tttgagtgcc
    17401 agcggcgttt gttaaaaatc cctggaaata tcgctgtagc ttgtcttgac ggttcagaca
    17461 attgcgatca aacacaccca actttgacat ccatccgtat tgactacaaa aaaatgggga
    17521 tagagacagg taagttactg attggactat tgaataataa tcatgatgaa tcagaagagt
    17581 cgcgtatcgt gcaattcaac taccagatag aattacgtca gagtacatga gcctaaaaga
    17641 gcgctattac aaagttagct attgtggtag gaatagccgt ttccggctat tccccgcgca
    17701 gatccggatg tatgctgcta acgcatccat tcctacttca ggtatttggc gtagaagcgg
    17761 atgctaaaaa cttgccgtaa aaccgcaata tcagcccgca gtgtcgctct ccagattatc
    17821 cattcctata ttgatgacaa cgacaggtaa gactgtgact caccaaactt ggatgttttt
    17881 ctgagcttaa agctcgttgc gtgaataagg cgagagtcag cgaatctcat cgaggcccgc
    17941 agcaccggct gcaataagga tatagagcag caatctaccg tcaacgtcaa aaacacggaa
    18001 gccttgcaaa cgggatgcgt tcatataaac aacatggagc agcaacagta cgatgcctgt
    18061 tgttgctcag tcaggacctt ttctgccatg cgcgagccag cgtcacgatt gatgaagaat
    18121 gttctcaact gattaattta ctgcaacaga cgtggctggt aataagcgct ggcggacaat
    18181 gcagggtgaa agactgtttt caggttgtcc gttcaggtat gttagatcag ttcgttgcgc
    18241 taaagacaac agttcagtcc cttatgttac ccgctatggc aaccattgtc cggtgataac
    18301 cgggcgtgtc atctgtgctt tcgttgattc ttatggactg ataaagtttt gtcagctgaa
    18361 tctttatacg gaattctttt cagtatgcgt acacgaattg attatctggc gaataaatac
    18421 tcttttacag agctgaatga atctccacgt cttcgccggc agtggcagga tgttctggag
    18481 gagtgccgac agacagaggc cgggccagaa gaacggttgc gtattgcact gctgaatgtg
    18541 gattacgtca ccagttttga actgcctttt cgcttgttgc ttacccgtac accacaactg
    18601 attgctgcgc tgcgtgaaga atggggcctc agccagaaaa atgtggtgtt caacgataaa
    18661 cgttttggct gcgtgtacag cctgaaggcc agcctttccg gtgtgccgga tacattccgg
    18721 tatcatctgt ctcatcgtat tcgccggatg gtcgggaatg aaaacacatc atcgccatac
    18781 caacagattg cccgggaagt gaaagcgccc cgtgaacggc tgaagcatgc gctggaggcg
    18841 gggttgctgg tgactgcact ggacggcctg ttctggttcg gcagtcagcg tattgcggct
    18901 gatgtcctga ggctgagaaa gagcggaatg ccggtggtga caacgaccgc ggaggtgcat
    18961 gataatctga cgggaacaac ccgcaaagta ccggcctacc atctctgatt cgaccatcag
    19021 ggggaatatt gctctggcag cagcagtacg acattcttta tccccgagcc tgaaaacatg
    19081 tgctaaggaa acgggaatgg caaggtccga ttacgatatt atcaatctgt ctccggaaca
    19141 tgaactgaat gagtggctgg cagagagagg ttatgccgga caggcggata accgtaaccg
    19201 ggtggcagaa attgttaccc gcaaattgca ggacagcttt tatatgaacg tttcctggga
    19261 tgcactgaac acggcatgca aggatgtctg ttttcctttc tcccctccgt aaaacacaac
    19321 tctgatcaca tttctgacat ttttcccgga ctttacataa caggattgtt tctgtatgtt
    19381 ttttatctgg tgtaaatttc agcactgaca ttccgcttac gttaatttac actggatatc
    19441 ccacgaggag aatatgcggc accggcagga taacttactg gcaaacagaa cattgttgcc
    19501 tggtatggtt tccggtcagt gcgcatttaa gctccgcact ttctctccgg tggcacgcta
    19561 tttttccctc ctcccctgcc tttgtattct ttcgttttcg tctccggcag ccatgctgtc
    19621 tccgggtgac cgcagtgcaa ttcagcagca acagcagcag ttgctggatg aaaaccagcg
    19681 tcagcgtgat gcgctggagc gcagtgcgcc gctgactatc acgccgtctc cggaaacgtc
    19741 tgccggtact gaaggcccct gctttacggt gtcacgcatt gttgtcagtg gggccacccg
    19801 actgacgtct gcagaaaccg acagactggt ggctccgtgg gtgaatcagt gtctgaatat
    19861 caccggcctg actgcggtca cggatgccgt gacggacggc tatatacgcc ggggatatat
    19921 caccagccgg gcctttctga cagagcagga cctttcaggg ggcgtactgc acataacggt
    19981 catggaaggc aggctgcagc aaatccgggc ggaaggcgct gaccttcctg cccgcaccct
    20041 gaagatggtt ttcccgggaa tggaggggaa ggttctgaac ctgcgggata ttgagcaggg
    20101 gatggagcag attaatcgtc tgcgtacgga gccggtacag attgaaatat cgcccggtga
    20161 ccgtgaggga tggtcggtgg tgacactgac ggcattgccg gaatggcccg tcacagggag
    20221 cgtgggtatc gacaacagcg ggcagaagaa taccggtacg gggcagttaa atggtgtcct
    20281 ttcctttaat aatccgctgg ggctggctga caactggttt gtcagcgtgg gacggagcag
    20341 tgacttttcg gtgtcacatg atgcgaggaa ttttgccgcc ggtgtcagtc tgccgtatgg
    20401 ctataccctg gtggattata cgtattcatg gagtgactac ctcagcacca ttgataaccg
    20461 gggctggcgg tggcgttcca cgggagacct gcagactcac cggctgggac tgtcgcatgt
    20521 cctgttccgt aacggggaca tgaagacagc actgaccgga ggtctgcagc accgcattat
    20581 tcacaattat ctggatgatg ttctgcttca gggcagcagc cgtaaactca cttcattttc
    20641 tgtcgggctg aatcacacac acaagtttct ggggggtgtc ggaacactga atccggtatt
    20701 cacacggggg atgccctggt tcggcgcaga aagcgaccac gggaaaaggg gagacctgcc
    20761 cgtaaatcag ttccggaaat ggtcggtgag tgccagtttt cagcgccccg tcacggacag
    20821 ggtgtggtgg ctgaccagcg cttatgccca gtggtcaccg gaccgtcttc atggtgtgga
    20881 acaactgagc ctcgggggtg agagttcagt gcgtggcttt aaggagcagt atatctccgg
    20941 taataacggc ggttatctgc gaaatgagct gtcctggtct ctgttctccc tgccatatgt
    21001 gggaactgtc cgtgcagtgg ctgcactgga cggcggctgg ctgcactctg acagagatga
    21061 cccgtactcg tccggcacgc tgtggggtgg tgctgccggg ctcagcacca ccagtgacta
    21121 tgtttccggt tcgttcactg ccgggctgcc tctggtttac ccggactggc ttgcccctga
    21181 ccatctcacg gtttactggc gcgttgccgt cgcgttttaa gggattatta ccatgaatca
    21241 gcctcccgtt cacttcactt accgcctgct gagttacctg gtcagtgcga ttatcgccgg
    21301 gcagccgttg ttaccggctg tgggggccgt catcacccca caaaacgggg ccggaatgga
    21361 taaagcggca aatggtgtgc cggtcgtgaa cattgccacg ccgaacgggg ccgggatttc
    21421 gcataaccgg tttacggatt acaacgtcgg gaaggaaggg ctgattctca ataatgccac
    21481 cggtaagctt aatccgacgc agcttggtgg actgatacag aataacccga acctgaaagc
    21541 gggcggggaa gcgaagggta tcatcaacga agtgaccggc ggtaaccgtt cactgctgca
    21601 gggctatacg gaagtggccg gcaaagcggc gaatgtgatg gttgccaacc cgtatggtat
    21661 cacctgtgac ggctgtggtt ttatcaacac gccgcacgcg acgctcacca cgggcagacc
    21721 tgtgatgaat gccgacggca gcctgcaggc gctggaggtg actgaaggca gtatcaccat
    21781 caatggcgcg ggcctggacg gcacccggag cgatgccgta tccattattg cccgtgcaac
    21841 ggaagtgaat gccgcgcttc atgcgaagga tttaactgtc actgcaggcg ctaaccggat
    21901 aactgcagat ggtcgtgtca gtgcactgaa gggcgaaggt gatgtgccga aagttgccgt
    21961 tgataccggc gcgctcggtg gaatgtacgc caggcgtatt catctgacct ccactgaaag
    22021 tggtgtcggg gttaatcttg gtaaccttta tgcccgcgat ggcgatatca ccctggatgc
    22081 cagcggcaga ctgactgtca acaacagtct cgccacgggg gccgtcactg caaaaggtca
    22141 gggcgtcacc ttaaccggcg accataaagc gggaggtaac ctgagcgtca gcagccggag
    22201 cgatatcgtt ctcagcaatg gaacgcttaa cagcgacaag gacctcagcc tgaccgccgg
    22261 cggcagaatc actcaacaga atgaaaaact gactgccggc cgggatgtaa cgcttgccgc
    22321 gaaaaacatc acacaggata ccgccagcca gattaacgcg gcccgcgata ttgtgactgt
    22381 cgccagtgac acgctgacaa cacagggaca gataaccgcc gggcggaatc tcacggccag
    22441 cgccaccacg ctgacacagg acggaatatt gctggcgaaa ggtcatgcgg gactcgatgc
    22501 cggcacgctg aataacagtg gtgctgttca gggggcttcc ctgacgctcg gcagtacaac
    22561 gctcagcaac agtggctccc tgctcagtgg cggtcccctg accgtgaata cccgcgactt
    22621 tacccagagc ggccgcactg gcgcgaaggg caaagtggat atcacggcca gtgggaaact
    22681 gaccagtaca ggttcgctgg tgagcgatga tgtactggtg ctgaaggcgc aggatgtgac
    22741 acagaacggt gtgctgtccg gcggcaaagg gctgacggtc agtgcgcagg cgctgagctc
    22801 cggtaaaaaa tcggtcaccc acagcgatgc tgcgatgacg ctgaatgtga caacagtggc
    22861 gctggacggg gaaaacagtg ccggtgacac cctcctggtt caggcagaca aactgagtac
    22921 cgcagcgggc gcacagcttc agagcggtaa aaatctcagc atcaacgcca gagatgcacg
    22981 tcttgcaggt acgcaggcag cacaacagac catggcggtg aacgccagtg aaaagctcac
    23041 ccacagcggg aaaagcagcg ccccgtcgct cagcctcagt gcgccggaac tgaccagcag
    23101 cggtgtgctt gttggttccg ccctgaatac acagtcacag accctgacca acagtggtct
    23161 gttgcagggg gaggcctcac tcaccgttaa cacacagagg cttgataatc agcagaacgg
    23221 cacgctgtac agtgctgcag acctgacgct ggatataccg gacatccgca acagcgggct
    23281 tatcaccagt gataatggtt taacgttaaa cactgcctcc ctcagcaatc cgggaaaaat
    23341 catcgctgac acgctgaacg tcagggcgac cacgctggat ggtgatggtc tgttgcaggg
    23401 cgccggtgca ctggcgcttg caggcgacac cctctcacag ggccgtaacg gacgctggct
    23461 gacggcgggc gacctctccc tccggggtaa aacactgcat accgcaggga ccacgcaggg
    23521 acagaatctc accgtgcagg cggacaactg ggcgaacagt ggctccgtgc tggcaaccgg
    23581 taaccttact gcttcggcaa ccggtcagtt gaccagtacc ggcgatatca tgagccaggg
    23641 tgacaccacg ctgaacgcag ccaccacgga caaccggggc agtctgcttt cggccggcac
    23701 gctctccctt gatggaaatt cactggataa ccgcggcact gtccagggtg accatgtcac
    23761 gattcgccag aacagtgtca ccaacagtgg cacgttcacc gggatcgccg cgctgacgct
    23821 tgccgcccgt atggcatccc ctcaacctgc gctgatgaat aacggaggtt cattgctgac
    23881 cagcggcgat ctgacaatca ccgcaggcag tattaccagt tccggacact ggcagggcaa
    23941 acgggtgctg atcaccgcag acagtctggc aaacagcggg gcgatccagg cggctgacag
    24001 cctgactgca cgtctgacgg gtgagctcgt cagcacagcg ggcagcaaag tcacctcgaa
    24061 cggtgaaatg gcgctcagtg cactgaattt aagcaacagc ggacaatgga ttgcaaaaaa
    24121 tctgaccctg aaggcgaact cactgaccag tgcgggtgac atcaccggtg tggatactct
    24181 cacgctcacg gtgaatcaga cgctgaacaa tcaggcgaac ggaaaactgc tcagtgcagg
    24241 tgtgctgacg ctgaaggcag acagtgtcac aaacgacggg caattacagg gaaatgtcac
    24301 caccatcacg gcaggacaac tcacaaacgg cgggcatctg cagggcgaaa cgctgacgct
    24361 ggccgcctcc ggtggcgtga acaaccgttc cggtggtgtt ctgatgagcc ggaatgcact
    24421 gaatgtcagt actgcgaccc tgagtaacca gggcacgata cagggtggtg gcggggtttc
    24481 cctgaacgcc acagaccgtc tgcagaacga cggcaaaatc ctctccggca gtaacctcac
    24541 gctgacggcg caggtgctgg cgaataccgg cagtggactg gtacaggctg ccaccctgct
    24601 gctggatgtg gtgaatactg tcaacggcgg acgcgtactt gccaccggca gtgccgacgt
    24661 taaaggaacc acgctgaata ataccggtac gcttcagggt acggacctgc tggtgaatta
    24721 ccacacattc agcaacagcg gtaccctgct gggaacctcc gggcttggcg tcaagggcag
    24781 ttcactgctg caaaatggta cagggcggct gtacagtgca ggcaacctgc tgcttgacgc
    24841 tcaggacttc agtggtcagg ggcaggtggt ggccaccggt gatgtcacac tgaaactgat
    24901 tgctgccctc acgaatcatg gtaccctggc cgcagggaaa accctttccg tcacgtcgca
    24961 aaatgccatc accaacggcg gtgtcatgca gggtgatgcc atggtgctcg gtgccggaga
    25021 ggcattcacc aacaatggaa cgctgactgc cggtaaaggc aacagtgttt tcagcgcaca
    25081 gcgtcttttc cttaacgcac cgggttcact tcagggcggt ggcgatgtga gtctgaacag
    25141 ccggagtgat atcaccatca gtggttttac cggcacggca ggcagtctga caatgaatgt
    25201 ggccggtacc ctgctgaaca gtgcgctgat ttatgcgggg aataacctga agctgtttac
    25261 agaccgtctg cataaccagc atggtgatat cctggccggc aacagtctgt gggtacagaa
    25321 ggatgcttcc ggcggtgcaa acacagagat tatcaatacc tccgggaata ttgagacgca
    25381 tcagggcgat attgttgtaa ggaccgggca tcttctgaac cagcgggagg gattttctgc
    25441 cacaacaaca acccggacta acccctcatc cattcaggga atgggaaatg ctctggttga
    25501 tattcccctt tcccttcttc ctgacggcag ctatggctat ttcacccgtg aagttgaaaa
    25561 tcagcacggt acgccctgca acgggcacgg ggcatgcaat atcacaatgg atacgcttta
    25621 ttattacgcg ccgtttgctg acagtgccac acagcgcttt ctcagcagcc agaacatcac
    25681 aacagtaacc ggtgctgata atccggcagg ccgcattgcg tcagggcgta atctttctgc
    25741 tgaggctgaa cgactggaaa accgggcgtc atttatcctg gcgaatgggg atatcgcact
    25801 ttcgggcaga gagttaagca atcagagctg gcagacgggg acagagaatg aatatctggt
    25861 ataccgctac gacccgaaaa cgttttacgg tagctatgcc acaggctctc tggataaact
    25921 gcccctgctg tcaccggaat ttgaaaacaa taccatcaga ttttcactgg atggccggga
    25981 aaaagattac acgcccggta agacgtatta ttccgttatt caggcgggcg gggatgttaa
    26041 gacccgtttt accagcagta tcaataacgg aacaaccact gcacatgcag gtagtgtcag
    26101 tccggtggtc tctgcacctg tactgaatac gttaagtcag cagaccggcg gagacagtct
    26161 gacacagaca gcgctgcagc agtatgagcc ggtggtggtt ggctctccgc aatggcacga
    26221 tgaactggca ggtgccctga aaaatattgc cggaggttcg ccactgaccg gtcagaccgg
    26281 tatcagtgat gactggccac tgccttccgg caacaatgga tacctggttc cgtccacgga
    26341 cccggacagt ccgtatctga ttacggtaaa cccgaaactg gatggtctcg gacaggtgga
    26401 cagccatttg tttgccggac tgtatgagct tcctggagcg aagccgggtc aggcgccacg
    26461 tgaaacggct ccgtcgtata ccgatgaaaa acagtttctg ggctcatcgt attttcttga
    26521 ccgcctcggg ctgaaaccgg aaaaagatta tcgtttcctg ggggatgcgg tctttgatac
    26581 ccggtatgtc agtaacgcgg tgctgagccg gacgggttca cgttatatca acggactggg
    26641 ttcagacacg gaacagatgc ggtatctgat ggataacgcg gccagacaac agaaaggact
    26701 gggattagag tttggtgtgg cgctgacagc tgaacagatt gctcagcttg acggcagcat
    26761 actgtggtgg gagtcagtca ccatcaacgg acagacagtc atggtcccga aactgtatct
    26821 gtcgccggaa gatatcaccc tgcataacgg cagcgttatc agcgggaaca acgtgcagct
    26881 tgcgggtggc aatatcacca acagcggcgg cagcatcaac gcacaaaacg gcctctcgct
    26941 cgacagtacc ggctatatcg acaacctgaa tgcggggctg ataagcgcgg gcggtagcct
    27001 ggacctgagc gccatcgggg atatcagcaa tatcagctca gtcatcagcg gtaaaaccgt
    27061 acaactggaa agcgtgagtg gcaacatcag caatatcacc cggcgtcagc aatggaatgc
    27121 gggcagtgac agccgatatg gtggtgtgca tctcagcggt acggacaccg gtccggttgc
    27181 gaccattaaa ggcactgatt cactttcact ggatgcaggg aaaaacattg atattaccgg
    27241 ggcaacggtc tcgtccggtg gaacccttgg aatgtctgcg ggtaatgata tcaacattgc
    27301 cgcaaacctg ataagcggga gcaaaagtca gtccggtttc tggcacactg atgacaacag
    27361 tgcatcatcc accacctcac agggcagcag catcagcgcc ggcggtaacc tggcgatggc
    27421 tgcaggccat aatctggatg tcacggcatc ctctgtttct gccgggcaca gcgccctgct
    27481 ttctgcaggt aacgacctga gtctgaatgc agtcagggaa agcaaaaaca gtcgcaacgg
    27541 caggtcagaa agtcatgaaa gccacgcagc agtgtccacg gtgacggcgg gcgataacct
    27601 cctccttgtt gctggtcgtg atgttgccag tcaggctgcc ggtgtggctg cggaaaataa
    27661 cgtggtcatc cggggcggac gtgatgtgaa cctggtggca gagtctgctg gtgcaggcga
    27721 cagctatacg tcgaagaaaa agaaagagat taacgagaca gtccgtcagc agggaacgga
    27781 aatcgccagc ggtggtgaca ccaccgtcaa cgcaggacgg gatatcaccg ctgttgcgtc
    27841 atccgttacc gcaaccggca atatcagcgt gaatgccggt cgtgatgttg ccctgaccac
    27901 ggcgacagaa agtgactatc actatctgga aacgaagaaa aaaagcggag gttttctcag
    27961 taagaaaacc acccacacca tcagtaagga cagtgcctcc cgtgaagcag gctccctgct
    28021 gtcggggaac cgcgtgaccg ttaacgccgg tgataacctg acggtagagg gttcggatgt
    28081 ggtggctgac caggatgtgt cactggcggc gggtaaccat gttgatgttc ttgctgccac
    28141 cagtacagat acgtcctggc gctttaagga aacgaagaaa tccggtctga tgggtaccgg
    28201 cggtattggt ttcaccattg gcagcagtaa gacaacgcac gaccgccgcg aggccgggac
    28261 aacgcagagt cagagtgcca gtaccatcgg ctccactgcc ggtaatgtca gtattaccgc
    28321 gggcaaacag gctcatatca gcggttcgga tgtgattgcg aaccgggata tcagcattac
    28381 cggtgacagt gtggtggttg acccggggca tgaccgtcgt actgtggacg aaaaatttga
    28441 gcagaagaaa agcgggctga cggttgccct ttccggcacg gtgggcagtg ccatcaataa
    28501 tgcggtcacc agtgcacagg agacgaagga gagcagtgac agccgtctga aagtcctgca
    28561 ggccacaaag acagcgctgt ctggtgtgca ggccggacag gctgcggcaa tggccaccgc
    28621 aaccggtgac ccgaatgcga cgggagtcag cctgtcgctt accacccaga aatcgaaatc
    28681 acaacaacat tctgaaagtg acacagtatc cggcagtacg ctgaatgccg ggaataatct
    28741 gtctgttgtc gcaaccggca aaaacagggg cgataaccgc ggagatattg tgattgcagg
    28801 aagccagctt aaggccggtg gtaacacaag cctggatgcc gcgaatgatg ttctgttgag
    28861 tggcgctgca aacacacaaa aaacaacggg caggaacagc agcagtggcg gtggcgtggg
    28921 tgtcagtatc ggtgccggtg gtaacggtgc cggtatcagc gtctttgcca gcgttaatgc
    28981 ggcaaaaggc agcgagaaag gtaacggtac tgagtggact gaaaccacaa tagatagcgg
    29041 taaaaccgtc accatcaaca gtggtcggga tacggtactg aacggtgctc aggtcaacgg
    29101 caacaggatt atcgccgatg tgggccacga cctgctgata agcagccagc aggacaccag
    29161 taagtacgac agtaaacaga ccagcgtggc tgccggcggc agttttacct ttggctccat
    29221 gaccggctca ggttacatcg ctgcctcccg ggataagatg aagagccgct ttgattccgt
    29281 tgctgaacaa accggaatgt ttgccggtga cggcggcttc gacattacag tgggcagaca
    29341 tacccaactg gatggtgcgg tgattgcctc cactgccaca ccggataaaa accacctgga
    29401 taccggaacg ctggggttca gtgaccttca caacgaagcg gattataaag tcagtcacag
    29461 tggaatcagt ctgagcggtg gtggcagctt cggggataaa tttcagggta acatgccggg
    29521 tggcatgata tccgccggag gtcacagcgg acatgcggaa ggaacgactc aggccgcagt
    29581 ggcagaaggc actatcacca tccgggacag ggacaatcag aagcagaatc tggcgaacct
    29641 gagccgtgac cctgtgcacg ctaatgacag tatcagcccg atatttgaca aggagaagga
    29701 gcagaggcgt ctgcagacag tggggcttat cagtgacatt ggcagtcagg tggcagatat
    29761 cgcgcggacg cagggggaac tgaatgcatt gaaggctgcg caggataaat atgggcctgt
    29821 tccggcggat gcgacggaag aacagcggca ggcatatctg gcaaaactgc gtgatacgcc
    29881 ggaatacaaa aaggaacagg aaaagtatgg cactggcagt gagattcagc gaggtataca
    29941 ggccgcgaca gccgcgcttc agggactggc gggtggtaat ttagcggggg ctctggccgg
    30001 agcttctgca ccggaactgg cgcatctgct gaaatcaaca gaaaaagacc cggcagtaaa
    30061 cgccattgct cacgccattc tgggcggtgc agtagcggca atgcagggta ataatgttgc
    30121 tgccggtgca gcaggcgcag caacgggaga gctggcagcc agagcgattg ccggaatgct
    30181 gtatccggga gtgaagcagt cagacctcag tgaagagcag aagcagacga taagtacgct
    30241 ggctactgtg tcagcagggc tggccggcgg tctaaccgga aacagcaccg catcagcagc
    30301 agtgggagca cagagcggga agaatgctgt tgagaataat taccttagtg aagagcagtc
    30361 tctgactttt gacaaggagc tatcggaatg ccggaattcc gggagggact gtcagaatgt
    30421 tatcgataaa tggaagaaaa tcagtgatga acagagtgca gaaatcgatc agaagctgaa
    30481 agacaatccg ctggaagccc aggttattga taaggaagtt gcgaagggcg gatatgatat
    30541 ggcgcagcgc ccaggttggc tgggtaacat tggtgtggaa gtaatgacca gtgatgaagc
    30601 caaagcctat gttcagcagt ggaatggacg ggatctgaca aaaatagatg taaacagccc
    30661 tgaatggact aagtttgcag tgtttgcttc tgatcctgaa aatcaggcca tgctggtcag
    30721 cggaggtttg ctggtaaaag atataactaa agcggctata tcattcatga gtcgcaatac
    30781 agcgacagcg acggtcaacg catcagaagt tggaatgcag tggggacagg gaaatatgaa
    30841 acagggtatg ccgtgggagg attatgttgg gaaatctctt cccgctgatg cccgtttacc
    30901 aaagaacttt aagacctttg attactatga tggtgctacc aaaactgcta ccagtgtaaa
    30961 atcaatggat acgcaaacta tggcgaaatt ggctaatccg aatcaggttt acagttcgat
    31021 aaaaggaaac atcgatgctg cggctaagtt taaagaatat gcactctctg ggcgagaatt
    31081 aacttcatca atgatctcta acagggagat acagctcgct attcctgctg acacaactaa
    31141 aacacagtgg gcagaaataa acagggctat tgagtacggt aaatctcagg gcgtcaaagt
    31201 gacggtaacg caggtgaaat aatggctttt aataaagatc aggattactg ggcgaatata
    31261 tttgttacac cagatttttt gagtgttgaa acttattcag gattaggaat gacaggcaga
    31321 gatccattgt tttcaccacg tttattacag cctgatgtag atgataaaag cctaggtgag
    31381 gagatcctac aggcattgtc tgacagccgt acactagatg ttttggaaga tcgagtagct
    31441 tttttcgatc ttgaaaaaag taaagagcaa tatgcagctt ggatagctac tctgatggag
    31501 aagtatggtt atagaactaa acgtgcatta tttaaaaaca tgaaaaaagt tggtatccat
    31561 ctggtaaatg atgttatcac aatccggcct tcattccatg aaaagctgga agcatggagt
    31621 ggtaacagga tcaatgaatc tgactatgtg gtgcttcctg cagacagttc cccaaccgaa
    31681 atcggctcag gtcttcgcct ggccttgagt cgctgcaaag gttaacctag atatcccgcc
    31741 catcactggc gggatttttg tgtgcttcca agcatatcat cttgacgcgt ttttcgggcg
    31801 cgcgtcatcg gcggcgcata cgaacgatcg tggtctgacg atggttgatt tattttgttg
    31861 cacaagggca acagcttatc tggtacccga ggctggctat gaagtgctga gtcgggtaat
    31921 tgcgtcatag tgggctcaaa cgtttgacga tgatgctgac cagaagctat tctggaccag
    31981 atcttacacc tctcaggcct cgttaaaata aaggaggaat gaatcgaacc agacagaaat
    32041 gaaaggccgg agttatagca gaggctaatc ctgagtaaaa cagtgcatca atactaggac
    32101 gttagtggag cacttttcat ctgacattga cagcaatgta tattatatcg gtttgaaccg
    32161 tcccgggaat cctggagact aaactccctg agaaagaggt aaacaggatg actaaaaata
    32221 ctcgtttttc ccccgaagtc cgtcagcgag cgattcgtat ggttctggaa agtcaggatg
    32281 agtatgattc acagtgggcg gcaatttgtt ccattgcccc aaaaattggc tgtacgccgg
    32341 agactctgcg tgtctgggtt cgccagcatg agcgggatac cgggggcggt gatggtgggc
    32401 tcaccaccgc tgaacgtcag cgtctgaaag agctggagcg tgaaaatcgt gaactgcgcc
    32461 gcagtaacga tatccttcgc caggcttccg cttattttgc gaaggcggag ttcgaccgcc
    32521 tctggaaaaa atgatgccgc tgctggataa gctgcgtgag cagtacgggg tcggaccggt
    32581 atgcagcgaa ctgcatattg ccccgtcaac gtattaccat tgtcagcaac agcgacatca
    32641 tccggataaa cgcagtgccc gtgcgcagcg cgatgactgg ctgaagaaag agatacagcg
    32701 cgtatacgat gaaaatcacc aggtatacgg tgtgcgtaaa gtctggcgtc agttgttacg
    32761 ggaaggtatc agagtggcca gatgcactgt ggcacgtctc atggcagtta tgggacttgc
    32821 cggtgttctc cggggtaaaa aggtccgcac taccgtcagc cagaaagccg ttgccgcagg
    32881 cgaccacgta aaccgtcagt tcgtggcaga acgtccagac cagttgtggg tggctgattt
    32941 tacctgggta agcacatggc agggcttcgt ttatgtggcg ttcatcattg atgtgttcgc
    33001 cggatacatc gtgggatggc gggtctcatc atccatggaa acggcattcg tgctggatgc
    33061 actggagcag gcgttgtggg cccgtcggcc gtccggcaca atccaccaca gtgataaagg
    33121 ttctcagtat gtatcgctga cctacacgca gcggcttaag gaagccggct tactggcatc
    33181 aacagggagt actggtgact cgtatgacaa cgcgatggcg gagagcatca atggccttta
    33241 caaagcggag gtaatacacc gtaagcgctg gaaaaaccgg acagaagtgg agctgtccac
    33301 acttacgtgg gtggactggt ataacaatcg acgattgctg gaaaggctgg gccatatccc
    33361 accggcagaa gcagaaaaag cttattatgc ttccatcgga aacgatgatc tggcagcctg
    33421 agttcacaga taaaacactc tcttggaaac ccggggcggt tcagacagta cataaatact
    33481 gcgcttccca gtcgataaac aacacggaaa aacgtcgttt ttttctgcgg gcgatatctg
    33541 caaccagatg aaataaaaca gtggaatcct tacctccgga aaaagacaga caaatctcct
    33601 caaaagtatc aaaaacccag ttaatccgtt ccacagcagc ccgggtaagc gtaaactgac
    33661 cgccgtatgt agccatcaga cgagaattgg taacttagac gcccatctga tatagacgga
    33721 catctaagta tggaattaca ggactggcga aaagaacctc gtaaaaacta ttcgaatgaa
    33781 ttcaaacttc gtatggtgga actggcatca caacctggag cttgtgttgc acagattgca
    33841 cgtgaaaatg gcgtcaatga taatgttatt ttcaaatggc tcaggctctg gcagaacgaa
    33901 gggcgtgttt cgcggcgtct tccggtaacg acctcttctg acactggcgt tgaattatta
    33961 cctgtagaaa taacgccgga tgagcagaaa gaacctgtgg cggccattgc gccgtcttta
    34021 tccacttcca ctcagaccag agtcagtgcc agttcctgca aggtggaatt ccgtcacggt
    34081 aacatgacgc tggaaaatcc atcgccagag ctgctcacgg tgttgatccg tgaactgacc
    34141 gggaggggaa gatgatctca ctcccatcag gtacccgtat ctggctcgtt gccggcgtta
    34201 ccgatatgcg taaatccttc aacggactgg gagaacaggt acaacatgtg ctgaatgata
    34261 atcccttctc cggtcacctg tttatcttcc gtggccgacg gggtgacacc gtcaaaattc
    34321 tttgggctga tgctga
//
LOCUS       DAPGUL010000042        33855 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.042, whole genome shotgun sequence.
ACCESSION   DAPGUL010000042 DAPGUL010000000
VERSION     DAPGUL010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33855
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.042"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(105..2174)
                     /gene="glyS"
                     /locus_tag="RHX21_002171"
     CDS             complement(105..2174)
                     /gene="glyS"
                     /locus_tag="RHX21_002171"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HDV1987346.1"
                     /translation="MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGT
                     VQWFAAPRRLALKVANLAEAQPDREIEKRGPAIAQAFDAEGKPSKAAEGWARGCGITV
                     DQAERLTTDKGEWLLYRAHVKGESTEALLPNMVATSLAKLPIPKLMRWGASDVHFVRP
                     VHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPEILRERGKVIAD
                     YEERKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPAEA
                     LVYTMKGDQKYFPVYANDGKLLPNFIFVANIESKDPQQIISGNEKVVRPRLADAEFFF
                     NTDRKKRLEDNLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAEQIGADVNHATRAGLL
                     SKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVAC
                     ALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLNLDLQTLTEEAV
                     RLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKA
                     VSHFRTLEAAAALAAANKRVSNILAKSDEVLSDRVNASTLKEPEEIKLAMQVVVLRDK
                     LEPYFAEGRYQDALVELAELREPVDAFFDKVMVMVDDKELRLNRLTMLEKLRELFLRV
                     ADISLLQ"
     gene            complement(2184..3095)
                     /gene="glyQ"
                     /locus_tag="RHX21_002172"
     CDS             complement(2184..3095)
                     /gene="glyQ"
                     /locus_tag="RHX21_002172"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HDV1987347.1"
                     /translation="MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMT
                     CLRALGPEPMAAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSL
                     KELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVT
                     GEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDF
                     LFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRI
                     RTLTKAVAEAYYASREALGFPMCNKDK"
     gene            complement(3190..3489)
                     /locus_tag="RHX21_002173"
     CDS             complement(3190..3489)
                     /locus_tag="RHX21_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YsaB family lipoprotein"
                     /protein_id="HDV1987348.1"
                     /translation="MMMNAFFPAMALMVLVGCSTPSPVQKAQRVKVDPLRSLNMEALC
                     KDQAAKRYNTGEQKIDVTAFEQFQGSYEMRGYTFRKEQFVCSFDADGHFLHLSMR"
     gene            3664..4659
                     /gene="wecH"
                     /locus_tag="RHX21_002174"
     CDS             3664..4659
                     /gene="wecH"
                     /locus_tag="RHX21_002174"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyltransferase WecH"
                     /protein_id="HDV1987349.1"
                     /translation="MQPKIYWIDNLRGIACLMVVMIHTTTWYVTNAHSVSPVTWDIAN
                     VLNSASRVSVPLFFMISGYLFFGERSAQPRHFLRIGLCLIFYSAIALLYIALFTSINM
                     ELALKNLLQKPVFYHLWFFFAIAVIYLVSPLIQVKNVGGKMLLVLMVVIGIIANPNTV
                     PQKIDGFEWLPINLYINGDTFYYILYGMLGRAIGMMDTQHKALSWVSAALFATGVFII
                     SRGTLYELQWRGNFADTWYLYCGPMVFICAIALLTLVKNTLDTRTIRGLGLISRHSLG
                     IYGFHALIIHALRTRGIELKNWPILDIIWIFCATLAASLLLSMLVQRIDRNRLVS"
     gene            complement(4701..5138)
                     /locus_tag="RHX21_002175"
     CDS             complement(4701..5138)
                     /locus_tag="RHX21_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312472.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiaB family inner membrane protein"
                     /protein_id="HDV1987350.1"
                     /translation="MDNKISTYSPAFSIVSWIALVGGIVTYLLGLWNAEMQLNEKGYY
                     FAVLVLGLFSAASYQKTVRDKYEGIPTTSIYYMTCLTVFIISVALLMVGLWNATLLLS
                     EKGFYGLAFFLSLFGAVAVQKNIRDAGINPPKETQVTQEEYSE"
     gene            complement(5184..5525)
                     /locus_tag="RHX21_002176"
     CDS             complement(5184..5525)
                     /locus_tag="RHX21_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709350.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987351.1"
                     /translation="MKTSKTVAKLLFVVGALVYLVGLWISCPLLSGKGYFLGVLMTAT
                     FGNYAYLRAEKLGQLDNFFTHICQLVALITIGLLFIGVLNAPINAYEMVIYPIAFFVC
                     LFGQMRLFRSV"
     gene            complement(5694..7148)
                     /gene="xylB"
                     /locus_tag="RHX21_002177"
     CDS             complement(5694..7148)
                     /gene="xylB"
                     /locus_tag="RHX21_002177"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HDV1987352.1"
                     /translation="MYIGIDLGTSGVKVILLNEQGEVVASQTEKLTVSRPHPLWSEQD
                     PEQWWQATDRAMKALGDQHSLQDVKALGIAGQMHGATLLDAQQRVLRPAILWNDGRCA
                     QECTLLEARVPQSRVITGNLMMPGFTAPKLLWVQRHEPEIFRQIDKVLLPKDYLRLRM
                     TGEFASDMSDAAGTMWLDVAKRDWSDVMLQACDLSRDQMPALYEGSEITGALLPEVAK
                     AWGMATVPVVAGGGDNAAGAVGVGMVDANQAMLSLGTSGVYFAVSEGFLSKPESAVHS
                     FCHALPQRWHLMSVMLSAASCLDWVAKLTGLCNVPALIAAAQQADESAEPVWFLPYLS
                     GERTPHNNPQAKGVFFGLTHQHGPNELARAVLEGVGYALADGMDVVHACGIKPQSVTL
                     IGGGARSEYWRQMLADISGQQLDYRTGGDVGPALGAARLAQIAANPEKSLIELLPQLP
                     LEQSHLPDAQRYAAYQPRRETFRRLYQQLLPLMA"
     gene            complement(7220..8542)
                     /gene="xylA"
                     /locus_tag="RHX21_002178"
     CDS             complement(7220..8542)
                     /gene="xylA"
                     /locus_tag="RHX21_002178"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HDV1987353.1"
                     /translation="MQAYFDQLDRVRYEGSKSSNPLAFRHYNPDELVLGKRMEEHLRF
                     AACYWHTFCWNGADMFGVGAFNRPWQQPGEALALAKRKADVAFEFFHKLHVPFYCFHD
                     VDVSPEGASLKEYINNFAQMVDVLAGKQEESGVKLLWGTANCFTNPRYGAGAATNPDP
                     EVFSWAATQVVTAMEATHKLGGENYVLWGGREGYETLLNTDLRQEREQLGRFMQMVVE
                     HKHKIGFQGTLLIEPKPQEPTKHQYDYDAATVYGFLKQFGLEKEIKLNIEANHATLAG
                     HSFHHEIATAIALGLFGSVDANRGDAQLGWDTDQFPNSVEENALVMYEILKAGGFTTG
                     GLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKIAARMIEDGELDKRIAQRYSGWNS
                     ELGQQILKGQMSLADLAKYAQEHNLSPVHQSGRQEQLENLVNHYLFDK"
     gene            8908..9900
                     /gene="xylF"
                     /locus_tag="RHX21_002179"
     CDS             8908..9900
                     /gene="xylF"
                     /locus_tag="RHX21_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose ABC transporter substrate-binding
                     protein"
                     /protein_id="HDV1987354.1"
                     /translation="MKIKNILLTLCTSLLLTNVAAHAKEVKIGMAIDDLRLERWQKDR
                     DIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEA
                     KQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDIVPQGNYFLMGGSPVDNN
                     AKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVAS
                     NDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTVYKPITLLANTAAE
                     IAVELGNGQEPKADTTLNNGLKDVPSRLLTPIDVNKNNIKDTVVKDGFHKESEL"
     gene            9978..11519
                     /gene="xylG"
                     /locus_tag="RHX21_002180"
     CDS             9978..11519
                     /gene="xylG"
                     /locus_tag="RHX21_002180"
                     /EC_number="7.5.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose ABC transporter ATP-binding protein"
                     /protein_id="HDV1987355.1"
                     /translation="MPYLLEMKNITKTFGSVKAIDNVCLRLNAGEIVSLCGENGSGKS
                     TLMKVLCGIYPHGSYEGEIIFAGEEIQASHIRDTERKGIAIIHQELALVKELTVLENI
                     FLGNEITHNGIMDYDLMTLRCQKLLAQVSLSISPDTRVGDLGLGQQQLVEIAKALNKQ
                     VRLLILDEPTASLTEQETSVLLDIIRDLQQHGIACIYISHKLNEVKAISDTICVIRDG
                     QHIGTRDAAGMSEDDIITMMVGRELTALYPNEPHTTGDEILRIEHLTAWHPVNRHIKR
                     VNDVSFSLKRGEILGIAGLVGAGRTETIQCLFGVWPGQWEGKIYIDGKQVDIRNCQQA
                     IAQGIAMVPEDRKRDGIVPVMAVGKNITLAALNKFTGGISQLDDAEEQKCILESIQQL
                     KVKTSSPDLAIGRLSGGNQQKAILARCLLLNPRILILDEPTRGIDIGAKYEIYKLINQ
                     LVQQGIAVIVISSELPEVLGLSDRVLVMHEGKLKANLINHNLTQEQVMEAALRSEHHV
                     EKQSV"
     gene            11497..12678
                     /gene="xylH"
                     /locus_tag="RHX21_002181"
     CDS             11497..12678
                     /gene="xylH"
                     /locus_tag="RHX21_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose ABC transporter permease XylH"
                     /protein_id="HDV1987356.1"
                     /translation="MSKSNPSEVKLAVPTSGGFSGLKSLNLQVFVMIAAIIAIMLFFT
                     WTTDGAYLSARNVSNLLRQTAITGILAVGMVFVIISAEIDLSVGSMMGLLGGVAAICD
                     VWLGWPLPLTIIVTLVLGLLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGT
                     TVSPTSAAMSQIGQSYLPASTGFIIGALGLMAFVGWQWRGRMRRQALGLQSPASTAVV
                     GRQALTAIIVLGAIWLLNDYRGVPTPVLLLTLLLLGGMFMATRTAFGRRIYAIGGNLE
                     AARLSGINVERTKLAVFAINGLMVAIAGLILSSRLGAGSPSAGNIAELDAIAACVIGG
                     TSLAGGVGSVAGAVMGAFIMASLDNGMSMMDVPTFWQYIVKGAILLLAVWMDSATKRR
                     S"
     gene            12756..13934
                     /gene="xylR"
                     /locus_tag="RHX21_002182"
     CDS             12756..13934
                     /gene="xylR"
                     /locus_tag="RHX21_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator XylR"
                     /protein_id="HDV1987357.1"
                     /translation="MFTKRHRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEED
                     FRARIDKIKDWLGDGVIADFDDKQIEQALADVDVPIVGVGGSYHLAESYPPVHYIATD
                     NYALVESAFLHLKEKGVNRFAFYGLPESSGKRWATEREYAFRQLVAEEKYRGVVYQGL
                     ETAPENWQHAQNRLADWLQTLPPQTGIIAVTDARARHILQVCEHLHIPVPEKLCVIGI
                     DNEELTRYLSRVALSSVAQGARQMGYQAAKLLHRLLDKEEMPLQRILVPPVRVIERRS
                     TDYRSLTDPAVIQAMHYIRNHACKGIKVDQVLDAVGISRSNLEKRFKEEVGETIHAMI
                     HAEKLEKARSLLISTTLSINEISQMCGYPSLQYFYSVFKKAYDTTPKEYRDVNSEVML
                     "
     gene            complement(14042..14866)
                     /locus_tag="RHX21_002183"
     CDS             complement(14042..14866)
                     /locus_tag="RHX21_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein bax"
                     /protein_id="HDV1987358.1"
                     /translation="MILTPIRRYGAMILMLLTLVFSSEVLAKTHTTTASQKSHLTKAS
                     NKQVSSKQEYSRNSAKSSSLPDLRKYPSGTPRKKAFLRTVMPYITSQNAAITAERNWL
                     ISKQYQGQWSPAERARLKDIAKRYKVKWSGNTRKIPWNTLLERVDIIPTSMVATMAAA
                     ESGWGTSKLARNNNNLFGMKCMKGRCTNAPGKVKGYSQFSSVKESVSAYVTNLNTHPA
                     YSSFRKSRAQLRKADQEVTATAMIHKLKGYSTKGKSYNNYLFAMYQDNQRLIAAHM"
     gene            15186..17216
                     /gene="malS"
                     /locus_tag="RHX21_002184"
     CDS             15186..17216
                     /gene="malS"
                     /locus_tag="RHX21_002184"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HDV1987359.1"
                     /translation="MKLAACFLTLLPGFAVAASWTSPGFPAFSEQGTGTFVSHAQLPK
                     GTRPLTLNFDQQCWQPADAIKLNQMLSLQPCSNTPPQWRLFRDGKYTLQIDTRSGTPT
                     LMISIQNAAEPVANLVRECPKWDGLPLTLDVSATFPEGAAVRDYYSQQIAIVKNGQIT
                     LQPAATSNGLLLLERAETDAPAPFDWHNATVYFVLTDRFENGDPSNDQSYGRHKDGMA
                     EIGTFHGGDLRGLTNKLDYLQQLGVNALWISAPFEQIHGWVGGGTKGDFPHYAYHGYY
                     TQDWTNLDANMGNEADLRTLVDSAHQRGIRILFDVVMNHTGYATLADMQEYQFGALYL
                     SGDEVKKTLGERWSDWKPAAGQTWHSFNDYINFSDKTGWDKWWGKNWIRTDIGDYDNP
                     GFDDLTMSLAFLPDIKTESTTASGLPVFYKNKTDTHAKVIEGFTPRDYLTHWLSQWVR
                     DYGIDGFRVDTAKHVELPAWQQLKTEASAALREWKKANPDKALDDKPFWMTGEAWGHG
                     VMQSDYYRHGFDAMINFDYQEQAAKAVDCLAQMDTTWQQMAEKLQGFNVLSYLSSHDT
                     RLFREGGDKAAELLLLAPGAVQIFYGDESSRPFGPTGSDPLQGTRSDMNWQDVSGKSA
                     ANVAHWQKISQFRARHPAIGAGKQTTLSLKQGYGFVREHGDDKVLVIWAGQQ"
     gene            17394..18647
                     /gene="avtA"
                     /locus_tag="RHX21_002185"
     CDS             17394..18647
                     /gene="avtA"
                     /locus_tag="RHX21_002185"
                     /EC_number="2.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--pyruvate transaminase"
                     /protein_id="HDV1987360.1"
                     /translation="MTFSLFGDKFTRHSGITLLMEDLNDGLRTPGAIMLGGGNPAQIP
                     EMQDYFQTLLTDMLESGKATDALCNYDGPQGKTELLTLLAGMLREKLGWDIEAQNIAL
                     TNGSQSAFFYLFNLFAGRRADGRVKKVLFPLAPEYIGYADAGLEEDLFVSARPNIELL
                     PEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELLKLDALANQHGIPLVID
                     NAYGVPFPGIIFSEARPLWNPNIVLCMSLSKLGLPGSRCGIIIANEKIITAITNMNGI
                     ISLAPGGIGPAMMCEMIKRNDLLRLSETVIKPFYYQRVQETIAIIRRYLPEDRCLIHK
                     PEGAIFLWLWFKDLPITTEQLYQRLKARGVLMVPGHNFFPGLDKPWPHTHQCMRMNYV
                     PEPEKIEAGVKILAEEIERAWAESH"
     gene            complement(18799..19272)
                     /locus_tag="RHX21_002186"
     CDS             complement(18799..19272)
                     /locus_tag="RHX21_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDV1987361.1"
                     /translation="MNRFIIADATKCIGCRTCEVACAVSHQENQDCAALSPDEFISRI
                     RVIKDHSWTTAVACHQCEDAPCANVCPVDAISREHGHIFVEQSRCIGCKSCMLACPFG
                     AMEVVSSRKKARAIKCDLCWHRETGPACVEACPTKALQCMDVEKVQRHRLRQQPV"
     gene            complement(19374..20222)
                     /gene="yiaJ"
                     /locus_tag="RHX21_002187"
     CDS             complement(19374..20222)
                     /gene="yiaJ"
                     /locus_tag="RHX21_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator YiaJ"
                     /protein_id="HDV1987362.1"
                     /translation="MGKEVMGKKENEMAQEKERPAGSQSLFRGLMLIEILSNYPNGCP
                     LAHLSELAGLNKSTVHRLLQGLQSCGYVTTAPAAGSYRLTTKFIAVGQKALSSLNIIH
                     IAAPHLEALNIATGETINFSSREDDHAILIYKLEPTTGMLRTRAYIGQHMPLYCSAMG
                     KIYMAFGHPDYVKSYWENHQHEIQPLTRNTITELPAMFDELAHIRESGAAMDREENEL
                     GVSCIAVPVFNIHGRVPYAVSISLSTSRLKQVGEKNLLKPLRETAQAISNELGFTVRD
                     DQGAIT"
     gene            20423..21421
                     /gene="yiaK"
                     /locus_tag="RHX21_002188"
     CDS             20423..21421
                     /gene="yiaK"
                     /locus_tag="RHX21_002188"
                     /EC_number="1.1.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydro-L-gulonate 2-dehydrogenase"
                     /protein_id="HDV1987363.1"
                     /translation="MKVTFEQLKAAFNRVLISRGVDSETADACAEMFARTTESGVYSH
                     GVNRFPRFIQQLENGDIIPDAQPKRITSLGAIEQWDAQRSIGNLTAKKMMDRAIELAA
                     DHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLI
                     VAIPSTPITMVDMSMSMFSYGMLEVNRLAGRQLPVDGGFDDEGNLTKEPGVIEKNRRI
                     LPMGYWKGSGMSIVLDMIATLLSDGASVAEVTQDNSDEYGISQIFIAIEVDKLIDGPT
                     RDAKLQRIMDYVTTAERADENQAIRLPGHEFTTLLAENRRNGITVDDSVWAKIQAL"
     gene            21433..21900
                     /locus_tag="RHX21_002189"
     CDS             21433..21900
                     /locus_tag="RHX21_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HDV1987364.1"
                     /translation="MIFGHIAQPNPCRLPAAIEKGLDFLRATDFNALEPGVVEIDGKN
                     IYAQIIDLTTREAVENRPEVHRRYIDIQFLAWGEEKIGIAIDTGNNKVSESLLEQRDI
                     IFYHDSEHESFIEMIPGSYAIFFPQDVHRPGCILQTASEIRKIVVKVALTALN"
     gene            22018..22491
                     /gene="yiaM"
                     /locus_tag="RHX21_002190"
     CDS             22018..22491
                     /gene="yiaM"
                     /locus_tag="RHX21_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate TRAP transporter small
                     permease YiaM"
                     /protein_id="HDV1987365.1"
                     /translation="MKKILEAILAINLAVLSCIVFINIILRYGFQTSILSVDELSRYL
                     FVWLTFIGAIVAFMDNAHVQVTFLVEKLSPAWQRRVALVTHSLILFICGALAWGATLK
                     TIQDWSDYSPILGLPIGLMYAACLPTSLVIAFFELRHLYQLITRSNSLTSPPQGA"
     gene            22494..23771
                     /gene="yiaN"
                     /locus_tag="RHX21_002191"
     CDS             22494..23771
                     /gene="yiaN"
                     /locus_tag="RHX21_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate transporter large permease
                     YiaN"
                     /protein_id="HDV1987366.1"
                     /translation="MAVLIFLGCLLGGIAIGLPIAWALLLCGAALMFWLDMFDVQIMA
                     QTLVNGADSFSLLAIPFFVLAGEIMNAGGLSKRIVDLPMKLVGHKPGGLGYVGVLAAM
                     IMASLSGSAVADTAAVAALLVPMMRSANYPVNRAAGLIASGGIIAPIIPPSIPFIIFG
                     VSSGLSISKLFMAGIAPGMMMGATLMLTWWWQASRLNLPRQQKATMQEIWHSFVSGIW
                     ALFLPVIIIGGFRSGLFTPTEAGAVAAFYALFVATVIYREMTFATLWHVLIGAAKTTS
                     VVMFLVASAQVSAWLITIAELPMMVSDLLQPLVDSPRLLFIVIMVAILIVGMVMDLTP
                     TVLILTPVLMPLVKEAGIDPIYFGVMFIINCSIGLITPPIGNVLNVISGVAKLKFDDA
                     VRGVFPYVLVLYSLLVVFVFIPDLIILPLKWIN"
     gene            23784..24770
                     /gene="yiaO"
                     /locus_tag="RHX21_002192"
     CDS             23784..24770
                     /gene="yiaO"
                     /locus_tag="RHX21_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate transporter
                     substrate-binding protein YiaO"
                     /protein_id="HDV1987367.1"
                     /translation="MKLRSVTYALFIAGLAAFSTSSLAAQSLRFGYETSQTDSQHIAA
                     KKFNDLLQERTKGELKLKLFPDSTLGNAQAMISGVRGGTIDMEMSGSNNFAGLSPVMN
                     LLDVPFLFRDTAHAHKTLDGKVGDDLKASLEGKGLKVLAYWENGWRDVTNSRAPVKTP
                     ADLKGLKIRTNNSPMNIAAFKVFGANPIPMPFAEVYTGLETRTIDAQEHPINVVWSAK
                     FFEVQKYLSLTHHAYSPLLVVINKAKFDGLSPEFQQALISSAQEAGNYQRKLVAEDQQ
                     KIIDGMKEAGVEVITDLDRKAFSDALGTQVRDMFVKDVPQGADLLKAVDEVQ"
     gene            24774..26270
                     /gene="lyxK"
                     /locus_tag="RHX21_002193"
     CDS             24774..26270
                     /gene="lyxK"
                     /locus_tag="RHX21_002193"
                     /EC_number="2.7.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-xylulokinase"
                     /protein_id="HDV1987368.1"
                     /translation="MTQYWLGLDCGGSWLKAGLYDREGREAGVQRLPLCALSPQPGWA
                     ERDMAELWQCCMAVIRELLTHSGVSGEQIVGIGISAQGKGLFLLDKNNKPLGNAILSS
                     DRRAMEIVRRWQEDGIPEKLYPLTRQTLWTGHPVSLLRWLKEHEPERYAQIGCVMMTH
                     DYLRWCLTGVKGCEESNISESNLYNMSLGEYDPCLTDWLGIAEINHALPPVVGSAEIC
                     GEITAQTAVLTGLKAGTPVVGGLFDVVSTALCAGIEDEFTLNAVMGTWAVTSGITRGL
                     RDGEAHPYVYGRYVNDGEFIVHEASPTSSGNLEWFTAQWGEISFDEINQAVASLPKAG
                     GDLFFLPFLYGSNAGLEMTSGFYGMQAIHTRAHLLQAIYEGVVFSHMTHLNRMRERFT
                     DVHTLRVTGGPAHSDVWMQMLADVSGLRIELPQVEETGCFGAALAARVGTGVYRDFSE
                     AQRDLQHPVRTLLPDMTAHQLYQQKYQRYQHLIAALQGFHARIKEHIL"
     gene            26267..26929
                     /gene="ulaD"
                     /locus_tag="RHX21_002194"
     CDS             26267..26929
                     /gene="ulaD"
                     /locus_tag="RHX21_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HDV1987369.1"
                     /translation="MSRPLLQLALDHSSLEAAQRDVMQLKDSVDIVEAGTILCLNEGL
                     GAVKALREQCPDKIIVADWKVADAGETLAQQAFGAGANWMTIICAAPLATVEKGHAMA
                     QRCGGEIQIELFGNWTLDDARDWHRIGVRQAIYHRGRDAQASGQQWGEADLARMKALS
                     DIGLELSITGGITPADLPLFKDIRVKAFIAGRALAGSANPAQVAGDFHAQIDAIWGGK
                     RA"
     gene            26922..27782
                     /locus_tag="RHX21_002195"
     CDS             26922..27782
                     /locus_tag="RHX21_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418039.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HDV1987370.1"
                     /translation="MRNHPLGIYEKALAKDLSWPERLVLAKSCGFDFVEMSVDETDER
                     LSRLDWSTAQRTSLVAAMIETGVGIPSMCLSAHRRFPFGSRDDAVRQRAREIMSKAIR
                     LARDLGIRTIQLAGYDVYYEDHDEGTRQRFAEGLAWAVEQAAASQVMLAVEIMDTAFM
                     NSISKWKKWDEMLASPWFTVYPDVGNLSAWGNDVPAELKLGIDRIAAIHLKDTQPVTE
                     QSPGQFRDVPFGEGCVDFVGIFKTLHKLNYRGSFLIEMWTEKAKEPVLEIIQARRWIE
                     ARMQEAGFIC"
     gene            27776..28471
                     /gene="araD"
                     /locus_tag="RHX21_002196"
     CDS             27776..28471
                     /gene="araD"
                     /locus_tag="RHX21_002196"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDV1987371.1"
                     /translation="MLEQLKADVLAANLALPAHHLVTFTWGNVSAVDETRQWMVIKPS
                     GVEYDVMTADDMVVVEIASGKVVEGSKKPSSDTPTHLALYRRYAEIGGIVHTHSRHAT
                     IWSQAGLDLPAWGTTHADYFYGAIPCTRQMTAEEINGEYEYQTGEVIIETFEERGRSP
                     AQIPAVLVHSHGPFAWGKNAADAVHNAVVLEECAYMGLFSRQLAPQLPAMQNELLDKH
                     YLRKHGANAYYGQ"
     gene            complement(28503..29318)
                     /locus_tag="RHX21_002197"
     CDS             complement(28503..29318)
                     /locus_tag="RHX21_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDV1987372.1"
                     /translation="MLELSMTLPIKVQNGGLFISRGVGRHPARRLESWEIIFVEKGRL
                     TIQEEERIFLVDAGESLLLWPNRQHVGVEDFPADLKFYWLHFEVKAPDSDPRWLTHLS
                     VPQQTKVVDPQALVALFRQFLSEQEKHQRTPALEFIVLLILQQLTRDARLDEQADGAG
                     TTLAWKAQKLIRTQYHRPLSTALLARELYCNADYLGRVYRRVFHLTLTEAIHRQRVRE
                     AEKLLISEARSLTEVAALCGFNDVGYFRQIFRKHTGLTPAAWKRRYSKEHINS"
     gene            29544..30944
                     /locus_tag="RHX21_002198"
     CDS             29544..30944
                     /locus_tag="RHX21_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1987373.1"
                     /translation="MTSTPITTADIAKGKIDDALSVREKIGYGLGDAGGTVITCLIMN
                     FLTFFYTDVFGLTPALVGTLFIALRVFDAISDPVMGVIADRTQSRWGRFRPWQLWIAI
                     PIGIIGILTFTVPDASMGVKITWAFGTYLLLSVGYTAINVPYCALINTMTTRHNEVIS
                     CQSWRFVLCGVAGFLVSVGLPWMVDLFGQGNAARGYQLGVGVLCAIAVVMFLCCFFWV
                     RERVPLSTMGKFTLREHLAGLRNNDQLLLMLVMSFLLINVFNIRGGGYMYFITYVLQG
                     STGYTSLFFTMVTFASIIGSVIVSPLTRRFDTVKIYYYTNLLLAALAVLMWFLPSGPA
                     YQTLWLAVILGNGVILGFTLPLHFSLMAFADDYGEWKTRVRSSGMNFAFNLFFIKLAW
                     ASSAGIISLLFIFVAYQPGVENQTASSLGGITAMETLLPALFHLLLAGAIRFCKLNNP
                     MMSRIATDLRQRHVQP"
     gene            30955..32934
                     /locus_tag="RHX21_002199"
     CDS             30955..32934
                     /locus_tag="RHX21_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003581012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 127 protein"
                     /protein_id="HDV1987374.1"
                     /translation="MNISEVDLRKLTVSDPFLGQYQQLVRDVVISYQWDALNDRIPEA
                     EPSHAIENFRIAAGLQEGEFYGMVFQDSDVAKWLEAVAWSLCQKPDAELEKTADEVIE
                     LIASAQCEDGYLNTYFTVKAPEERWSNLAECHELYCAGHLIEAGVAFFQATGKRRLLE
                     VVCRLADHIDRVFGPDEDKLQGYPGHPEIELALMRLYEVTEEPRYLALTNYFVEQRGV
                     QPHYYDQEYEKRGQTSHWHTYGPAWMVKDKAYSQAHLPLAQQQTAIGHAVRFVYLMTG
                     VAHLARLSHDDSKRQDCLRLWNNMAQRQLYITGGIGSQSSGEAFSSDYDLPNDTVYAE
                     SCASIGLMMFARRMLEMEGDSQYADVMERALYNTVLGGMALDGKHFFYVNPLEVHPKS
                     LKFNHIYDHVKPIRQRWFGCACCPPNIARVLTSIGHYLYTPREDALYINIYAGNSMEV
                     PVENGTLRLRVSGNYPWQEQVTIAVESPQPVRHTLALRLPDWCTQPQIILNGEEVEQD
                     IRKGYLHITREWQEGDTLNLTLPMPVRRVYGNPLVRHVAGKVAIQRGPLVYCLEQADN
                     GESLHNLWLPTDAPFTTFEGKGLFSHKILIQAPGYRYEQSNPEQQPLWHYDSAPAKRQ
                     PQTLTFIPWFSWANRGEGEMRIWVNEEKHRHPEVG"
     gene            complement(33055..33795)
                     /locus_tag="RHX21_002200"
     CDS             complement(33055..33795)
                     /locus_tag="RHX21_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MipA/OmpV family protein"
                     /protein_id="HDV1987375.1"
                     /translation="MLINRNIVALFALPFMASATASELSIGAGAAYNESPYRGYNENT
                     KAIPLISYEGDSFYVRQTTLGFILSQSEKNELSLTASWMPLEFDPADNDDYAMQQLDK
                     RDSTAMAGVAWYHHERWGTVKASAAADVLDNSNGWVGELSVFHKMQIGRLSLTPALGV
                     LYYDENFSDYYYGISESESRRSGLASYSAQDAWVPYVSLTAKYPIGEHVVLMASAGYS
                     ELPEEITNSPMIDRNESFTFVTGVSWRF"
BASE COUNT         8254 a         8751 c         8550 g         8300 t
ORIGIN      
        1 tatgagataa tctttattca gcagaagatt attaaaggtt gctgtattat ttagcgataa
       61 taaaaaaagc ctgccagatg gcaggctttt taataacggc gttattactg caacagcgaa
      121 atatccgcaa cgcgcaggaa cagttcgcgc agtttctcca gcatggtcag acggttgaga
      181 cgcaattctt tgtcatcaac catgaccatc actttatcga agaaagcatc aaccggctca
      241 cgcagctctg ccagttcgac cagcgcatcc tggtaacgac cttccgcaaa gtacggctcc
      301 agcttgtcac gtagcaccac aacctgcatc gccagtttaa tttcttccgg ctctttcagg
      361 gtagaggcat tcacgcggtc gctcagcact tcgtcagatt tcgccaaaat gttggagaca
      421 cgcttgttcg ccgccgccag tgcagcagct gcttcaaggg tacggaagtg cgataccgct
      481 ttcatgcggg catcgaaatc agccggacga gtcggacgac gcgccagtac cgcctggatg
      541 gtgtcaacgg tgtaaccttc gtcctgatac caggcgcgga agcgaccgag cataaagtcg
      601 ataacatcat caaccacgtt ggcgttagtc agcttatcgc catacagacg cactgcttct
      661 tcggtcagcg tttgcagatc aaggttgagg ttcttctcaa cgataattcg cagcacgcca
      721 agtgcggcac gacgcagcgc aaacgggtct ttgtcgcctt tcggatgctg gccgataccg
      781 aagatacccg ccagagtatc catcttgtca gcaatcgcca gcgcacaggc taccgggtta
      841 gacggcaggt catcaccggc aaagcgcggc tgatactgct cattcagcgc caccgcgaca
      901 tcttccgctt cgccatcgtg acgcgcatag tgcatcccca taacgccctg ggtgtcggtg
      961 aactcgaaga ccatgttggt catcaggtca cacttagaca gcaggcccgc acgggttgcg
     1021 tggttaacgt cagcgccaat ctgttcagca atccagccag ccagcgcctg gatgcggtca
     1081 gttttgtcgc gcagcgtacc cagctgttgc tggaacagca cggtttgcag gcgcggcagg
     1141 ttatcttcca gacgtttttt acggtcggta ttgaagaaga actcggcatc cgccagacgt
     1201 ggacgaacga ctttctcgtt accagagata atttgctgcg gatctttcga ttcgatgttg
     1261 gcaacgaaga tgaagttcgg cagcagtttg ccatcgttcg catacaccgg gaagtatttc
     1321 tggtcacctt tcatggtgta aaccagggct tcagccggca ccgcgaggaa tttctcttcg
     1381 aattttgcgg tcagaacgac cggccactcc accagcgaag ccacttcttc cagcaggctt
     1441 tcgcttaagt cagcgttacc gccaatctta cgcgctgctt cttcggcatc ggctttaatc
     1501 ttcgctttac gttcttcgta atcggcgatg actttcccgc gctcacgcag aatttccgga
     1561 tactgatcgg cgttgtcgat ggtgaattcc ggttcgccca taaagcggtg gccgcgaatc
     1621 acgcgatcgg actgaatgcc cagaatggtt gccggaatga ctttgtcgcc cagcagcagg
     1681 gtcacggtgt gcaccggacg cacgaagtgc acgtcgcttg cgccccaacg catcagtttc
     1741 gggatcggca gtttcgccag agaagtcgca accatattcg gcagcagtgc ttcggtgctt
     1801 tcgcccttca catgggcgcg atacagcagc cattcgcctt tatcggtagt cagacgctca
     1861 gcctggtcaa cggtaatacc gcaaccacgc gcccaacctt ctgccgcttt gctcggtttg
     1921 ccttcagcgt cgaacgcctg ggcaatcgcc gggccgcgtt tttcgatttc acgatccggt
     1981 tgcgcttccg ccaggttagc tactttcagc gccagacgac gcggagcagc aaaccattga
     2041 acggtgccgt gtgcgaggcc agcgttatcc agctccgcag taaaattcgc agcaaaggac
     2101 tcagccaggc tgcgcagtgc ttttggtggc agctcttcag tgccgatttc caccagaaaa
     2161 gttttctcag acatagccgc ctcttactta tctttgttgc acatcgggaa gccgagggct
     2221 tcacgggaag cgtagtatgc ttctgccact gctttggtca gggtgcgaat gcgcagaatg
     2281 tagcgctgac gctcggtgac ggagatggct ttacgcgcat ccagcaggtt gaagctgtgg
     2341 gcggctttca gaatacgctc gtaggctggc agcggcagcg gattttccag cgccagcagc
     2401 tgctgcgctt ctttctcgta ctgctcaaag caggtgaaca ggaagtccac atccgcgtat
     2461 tcgaagttgt aagtggactg ctccacttcg ttctgatgga acacgtcgcc gtaggtggtt
     2521 ttacccagcg ggccgtcgct ccagaccagg tcgtaaacgc tgtctacgcc ctgaatgtac
     2581 atggccagac gttccagacc gtaggtgatc tcgccggtaa ccggtttaca ctccagacca
     2641 ccaacctgct ggaagtaagt gaactgcgtc acttccatgc cgtttagcca cacttcccag
     2701 cccagtcccc aggcacccag agtcgggttt tcccagttat cttccacgaa acggatgtcg
     2761 tgaatagtcg ggtccatgcc cagctctttc agagaaccga ggtacagctc ctgaatattg
     2821 tccggcgatg gcttaatgac cacctggaac tgatagtagt gctgtaaacg gttggggttt
     2881 tcgccgtagc gaccatcggt cgggcgacga gaaggctgaa cataagcagc cgccatcggt
     2941 tctggcccca gcgcgcgcag acaggtcatt gggtgagagg ttcccgcgcc gacttccatg
     3001 tccaatggtt gaacaatggt gcagccctgg cgagcccagt aatcctgtaa ggtcaggatc
     3061 aagccctgga aggtcctggt atcaaacttt tgcatattat ttcgtgctgg atacgtgtgg
     3121 atttaaagga agggatcagt atacccgctg gatggaagat atacagtacg aaacgggaaa
     3181 aagcagggct taacgcatgg aaagatgcaa aaaatggcca tctgcgtcaa aagaacagac
     3241 aaactgctct ttacggaagg tataaccgcg catttcatag cttccctgga actgttcgaa
     3301 ggcggtgacg tcgatttttt gctcgccggt gttataacgt tttgccgcct gatccttgca
     3361 taacgcttcc atattcaacg aacgcagagg atcaaccttt acccgttgtg ctttctgcac
     3421 gggtgacggt gtagaacaac ccactagcac cataagcgcc attgccggaa agaaagcgtt
     3481 catcatcatt aaattaccgt ctggtttgca ggtgagtctt attatttata tcggtatagt
     3541 ggctgatatc ttacgaattt ccttaagcct ctataagctg tagtgataaa actcagatta
     3601 ttccagtgcg ccaaccaaat gatttatcgg tcagactttt tttaaccaga tacagagaca
     3661 cagatgcagc ccaaaattta ctggattgat aacctgcgag ggatagcgtg tttaatggtg
     3721 gtgatgattc acaccactac ctggtatgtg accaatgctc atagtgttag ccccgtcaca
     3781 tgggatatcg ccaatgttct gaattctgcc tctcgtgtca gcgtgccgct atttttcatg
     3841 atttccggct atctcttttt tggcgaacgc agcgcccagc cgcgccattt cttgcgtatc
     3901 ggcttatgtc tgatttttta tagcgcaatc gcactgctct acattgcgct gtttacctcc
     3961 atcaatatgg agttagcgct gaaaaacctg ctgcaaaagc cagtgtttta ccacttgtgg
     4021 tttttcttcg cgattgcggt gatttatctg gtttcaccgc tgattcaggt gaagaacgtc
     4081 ggcggaaaaa tgttgctggt gctaatggtg gtgattggca ttatcgctaa cccaaacaca
     4141 gtgccgcaga aaattgacgg ttttgaatgg ctgccaatta acttatatat caatggcgat
     4201 actttttact acattctgta tggcatgttg ggccgcgcta tagggatgat ggacacacag
     4261 cataaagcac tgtcgtgggt gagcgccgcg ctgtttgcga cgggggtttt tattatctct
     4321 cgcgggacat tatatgaatt gcagtggcgc ggaaattttg ccgatacctg gtatctttac
     4381 tgtgggccga tggtttttat ctgcgcaatc gcgctattga ctctggttaa aaacacgctg
     4441 gatacgcgta ccattcgcgg acttggctta atctcccgcc attcattggg tatatacgga
     4501 ttccacgcct tgattatcca tgcgctgcgc acccggggaa ttgagcttaa aaattggcca
     4561 atactggata ttatttggat cttttgcgcg acgttggcag cgagtttgtt actttctatg
     4621 ctggtacaac gaatcgacag aaacagatta gtgagttaag taaaagcccg ttcacattgg
     4681 actgaccggg cttacgtgaa ttattcgctg tattcttcct gggtaacctg tgtttctttt
     4741 ggcgggttta ttccggcatc acgaatattc ttctgcaccg ctactgcacc aaacaagctt
     4801 aagaagaaag ccagtccata aaaacctttt tcactgagta ataatgtcgc attccacaga
     4861 cctaccatca gtaatgcaac agagataata aagacagtca ggcaggtcat ataataaatg
     4921 gaagtggtcg gtatgccttc atacttgtcc cgaacggtct tttgataaga cgcagcagaa
     4981 aacagtccta acaccagtac ggcaaaataa tacccttttt catttaactg catctctgca
     5041 ttccatagcc ctaacagata ggtaacgata ccaccaacga gagctatcca tgacacaata
     5101 ctaaaggccg gtgaataggt tgatattttg ttgtccatca cagtattcct ttcattcctg
     5161 aatgtgtaag agctttatgt tgctcatacc gagcgaaaca aacgcatttg accaaacaag
     5221 cagacaaaaa aggcgatggg gtagatcacc atttcataag cattgatagg tgcatttaaa
     5281 acaccgataa acaagagacc gatagtgatt aacgcaacta actggcagat atgggtaaaa
     5341 aaattatcca gttgcccgag tttttctgcg cgaagatatg catagttacc aaaagttgct
     5401 gtcattaaca cgccaagaaa atagcctttt ccacttagca atgggcatga gatccatagc
     5461 ccaaccagat aaaccagcgc cccgacaaca aataatagtt ttgccacagt ttttgaggtt
     5521 ttcataacga tctccatatc taccagcgat acattacgag taaccaacga aagacaaaac
     5581 tgaaaaatgc cattaacaaa tgattttcag aataaattca tactaaatat taattaatta
     5641 gtgagatata tagatgtgaa ttatccccca cccggtcagg caggggataa cgtttacgcc
     5701 attaatggca gaagttgctg atagaggcga cggaacgttt cacgtcgtgg ctgataagcg
     5761 gcataacgct gcgcatctgg tagatgcgac tgttctaacg gtagctgcgg caacaactca
     5821 atgagcgatt tctctggatt cgccgcaatc tgcgccagcc ttgctgcgcc cagtgctggc
     5881 cccacatccc cccccgtacg gtaatcgagc tgctgaccgc tgatatccgc cagcatctga
     5941 cgccagtact cactacgcgc cccgccacca atcaacgtaa cactttgcgg tttaatgccg
     6001 caggcatgca cgacatccat gccatctgcc agcgcataac ccacgccttc cagcactgct
     6061 cgcgccagtt cattggggcc atgttgatga gtcaaaccaa agaaaacccc cttcgcctgg
     6121 ggattattgt gtggtgtacg ctcgccggaa agataaggca gaaaccaaac tggctcggca
     6181 ctttcatcag cctgttgagc tgcagcgatt aaagctggga cattgcacag gccggttaat
     6241 ttcgcgaccc aatccagaca cgatgctgca ctcagcatta cagacattaa atgccaacgc
     6301 tgcggtagcg catggcaaaa gctgtgtaca gcgctttctg gcttgcttaa gaacccttcg
     6361 ctgacagcaa aatagacccc cgacgtcccc agcgataaca ttgcctgatt agcatcaacc
     6421 attcccacac caactgcacc agctgcattg tcgccaccgc ctgcaacaac tggcaccgtc
     6481 gccatacccc acgctttcgc aacttcaggt aacaaagcac cagtaatttc gctgccttcg
     6541 tataatgcgg gcatctggtc acgagataag tcgcaagcct gcagcatgac gtcactccag
     6601 tcacgctttg cgacatccag ccacatggtg ccagctgcgt cagacatatc gctggcaaac
     6661 tcccccgtca tacgcagacg caagtaatct ttcggtaata atactttgtc gatttgacgg
     6721 aatatctccg gctcatgccg ctgaacccat agcaatttag gcgcagtaaa tccgggcatc
     6781 atcaggttgc cggtaatcac tcgtgattgc ggaactctcg cttccagcaa agtgcactct
     6841 tgcgcacagc gcccgtcgtt ccacaaaatg gcagggcgca atacccgttg ttgagcatcc
     6901 agtaaggttg ctccatgcat ctggccggca atacccaatg ctttaacgtc ctgcagagaa
     6961 tgctgatcgc ccagagcttt cattgcgcga tcagttgcct gccaccactg ttccgggtct
     7021 tgttccgacc agagtggatg cgggcgcgaa acggtcagct tttccgtttg cgaagcaacc
     7081 acctcaccct gctcgttgag caaaataact tttacgcccg aggtgccaag atctatcccg
     7141 atatacatat cgatcgttcc ttaaaaaaat gcccggtatc gctaccgata accgggccaa
     7201 cggactgcac agttagccgt tatttgtcga acagataatg atttaccaga ttttccagtt
     7261 gctcctggcg accactctga tgcaccggag acaaattatg ttcctgagca tatttggcta
     7321 aatctgccag tgacatttgg cctttcagga tttgctggcc caattcgcta ttccagccgg
     7381 aataacgctg cgcgatgcgt ttatccagct cgccatcttc aatcatgcgc gctgcaattt
     7441 tcagcgccag tgccatcgta tccatcgcgc cgatatgacc gtaaaacaga tcatatttat
     7501 cagtactttg acgacgtact ttggcatcga agttcagacc accggtggtg aaaccgcctg
     7561 ctttgagaat ttcatacatc accagcgcat tctcttccac actgttcggg aactggtcgg
     7621 tgtcccagcc cagttgcgca tcgccacggt tggcgtcgac agaaccgaac aggccaagcg
     7681 caatggcggt ggcaatttca tgatggaaag agtgacctgc cagcgtcgcg tggttagctt
     7741 caatgttcag tttaatctct ttttccagac caaactgttt caggaagcca tagaccgtcg
     7801 cggcatcgta atcatattga tgtttggtcg gttcttgcgg tttcggttcg ataagcaacg
     7861 tgccctggaa accgatttta tgtttatgct caaccaccat ctgcataaag cggcccagct
     7921 gttcacgctc ctgacgcaag tcggtattta acagcgtttc gtaaccttca cgaccgcccc
     7981 acaggacata gttttcaccg cccaatttat gggttgcttc catcgctgta acaacttgcg
     8041 ttgccgccca actgaagact tcaggatctg ggttcgtcgc cgcacccgcg ccatagcgag
     8101 ggtttgtaaa gcagttagcg gttccccaca gcagcttcac gccgctctct tcttgcttgc
     8161 ctgccaggac atcaaccatt tgcgcaaaat tattgatgta ctcttttaac gacgcgccct
     8221 caggggaaac atccacatcg tggaagcaat aaaatggcac atgtaacttg tggaaaaact
     8281 caaatgcgac atctgcttta cgcttcgcca acgccagtgc ctcaccaggc tgctgccacg
     8341 gacgattaaa cgcccccaca ccaaacatgt ccgccccgtt ccagcagaat gtgtgccagt
     8401 agcaggcggc aaaacgcaag tgctcttcca tacgcttgcc caacaccagt tcgtcgggat
     8461 tgtagtgacg gaatgctaac gggtttgagg attttgagcc ttcataacga acgcgatcga
     8521 gctggtcaaa ataggcttgc atattgaact ccataatcag gtaatgccgc gggtgatgga
     8581 tgatgtcgta atattgggca ctccctttca gttgctcaat tatgttattt cacactgcta
     8641 ttgagataat tcacaagtgt gcgctcgctc gcaaaataaa atggaatgat gaaactgggt
     8701 aattcctcga agagaaaaat gcaataagta caattgcgca acaaaagtaa gatctcggtc
     8761 ataaatcaag aaataaacca aaaatcgtaa tcgaaagata aaaatctgta attgttttcc
     8821 cctgtttagt tgctaaaaat tggttacgtt tatcgcggtg attgttactt attaaagctg
     8881 tcctctaact acagaaggcc ctacaccatg aaaataaaga acattctact caccctttgc
     8941 acctcacttc tgcttaccaa cgttgcggca cacgccaaag aagtcaaaat aggtatggcg
     9001 attgatgatc tccgtcttga acgctggcaa aaagatcgag atatttttgt gaaaaaggca
     9061 gaatctctcg gcgcgaaagt atttgtacag tctgcaaatg gcaatgaaga aacacaaatg
     9121 tcgcagattg aaaacatgat aaaccggggt gtcgatgttc ttgtcattat tccgtataac
     9181 ggtcaggtat taagtaacgt tgtaaaagaa gccaaacaag aaggtattaa agtattagct
     9241 tacgatcgta tgattaacga tgcggatatc gatttttata tttctttcga taacgaaaaa
     9301 gtcggtgaac tgcaggcaaa agccctggtc gatattgttc cgcaaggtaa ttacttcctg
     9361 atgggcggct cgccggtaga taacaacgcc aagctgttcc gcgccggaca aatgaaagtg
     9421 ttaaaacctt acgttgattc cggaaaaatt aaagtcgttg gtgaccaatg ggttgatggc
     9481 tggttaccgg aaaacgcatt gaaaattatg gaaaacgcgc taaccgccaa taataacaaa
     9541 attgatgctg tagttgcctc aaacgatgcc accgcaggtg gggcaattca ggcattaagc
     9601 gcgcaaggtt tatcagggaa agtagcaatt tccggccagg atgcggatct cgcaggtatt
     9661 aaacgtattg ctgccggtac gcaaactatg acggtgtata aacctattac gttgttggca
     9721 aatactgccg cagaaattgc cgttgagttg ggcaatggtc aggaaccaaa agcagatacc
     9781 acactgaata atggcctgaa agatgtgccc tcccgcctcc tgacaccgat cgatgtgaat
     9841 aaaaacaaca tcaaagacac ggtagttaaa gacggattcc acaaagagag cgagctgtaa
     9901 gcgttacgcc ccggcgcgga gcgggggcgt gatttctctc catgccgcgt gaatgaattg
     9961 gcttaggtgg agtcgttatg ccttatctac ttgaaatgaa gaacattacc aaaaccttcg
    10021 gcagtgtgaa ggcgattgat aacgtctgct tgcggttgaa tgctggcgaa atcgtctcac
    10081 tttgtgggga aaatgggtct ggtaaatcaa cgctgatgaa agtgctgtgt ggtatttatc
    10141 cccatggctc ctacgaaggc gaaattattt ttgcgggaga agagattcag gcgagtcaca
    10201 tccgcgatac cgaacgcaaa ggtatcgcca tcattcatca ggaattggcc ctggtgaaag
    10261 aattgaccgt gctggaaaat atcttcctgg gtaacgaaat aacccacaat ggcattatgg
    10321 attatgacct gatgacgcta cgctgtcaga agctgctcgc acaggtcagt ttatccattt
    10381 cacctgatac ccgcgttggc gatttagggc ttgggcaaca acaactggtt gaaattgcca
    10441 aggcacttaa taaacaggtg cgcttgttaa ttctcgatga accgacagcc tcattaactg
    10501 agcaggaaac gtcggtttta ctggatatta ttcgcgatct acaacagcac ggtatcgcct
    10561 gtatttatat ttcgcacaaa ctcaacgaag tcaaagcgat ttccgatacg atttgcgtta
    10621 ttcgcgacgg acagcacatt ggtacgcgtg atgctgccgg aatgagtgaa gacgatatta
    10681 tcaccatgat ggtcgggcga gagttaaccg cgctttaccc taatgaacca cataccaccg
    10741 gagatgaaat attacgtatt gaacatctga cggcatggca tccggtcaat cgtcatatta
    10801 aacgagttaa tgatgtctcg ttttccctga aacgtggcga aatactgggt attgccggac
    10861 tcgttggtgc cggacgtacc gagaccattc agtgcctgtt tggcgtgtgg cccggacaat
    10921 gggaaggaaa aatttatatt gatggcaaac aggtagatat tcgtaactgt cagcaagcca
    10981 tcgcccaggg gattgcgatg gtacccgaag acagaaagcg cgacggcatc gttccggtaa
    11041 tggcggttgg taaaaatatt accctcgccg cactcaataa atttaccggt ggcattagcc
    11101 agcttgatga cgcggaagag caaaaatgta ttctggaatc aattcagcaa ctcaaagtta
    11161 aaacgtcgtc ccccgatctt gctattggac gtttgagcgg cggcaatcag caaaaagcga
    11221 tcctcgcccg ctgtctgtta ctcaacccgc gcattctcat tcttgatgaa cctaccaggg
    11281 gtattgatat tggcgcgaaa tatgagatct acaaattaat taaccaactc gtccagcagg
    11341 gtattgccgt tattgtcatc tcttccgaat tacctgaagt gctcggcctt agcgatcgtg
    11401 tactggtgat gcatgaaggg aaactaaaag ccaacctgat aaatcataac ctgactcagg
    11461 agcaggtgat ggaagccgca ttgaggagcg aacatcatgt cgaaaagcaa tccgtctgaa
    11521 gtgaaattgg ccgtaccgac atccggtggc ttttctgggc tgaaatcact gaatttgcag
    11581 gtcttcgtga tgattgcagc tatcatcgca atcatgctgt tctttacctg gaccaccgat
    11641 ggtgcctact taagcgcccg taacgtctcc aacctgttac gccagaccgc gattaccggc
    11701 atcctcgcgg taggaatggt gttcgtcata atttctgctg aaatcgacct ttccgtcggc
    11761 tcaatgatgg ggctattagg tggcgtcgcg gcgatttgtg acgtctggtt aggctggcct
    11821 ttgccactta ccatcattgt gacgttggtt ctgggactgc ttctcggtgc ctggaacgga
    11881 tggtgggtcg cgtaccgcaa agtcccttca tttattgtca ccctcgcggg catgttggca
    11941 tttcgcggca tactcattgg catcaccaac ggcacgactg tatcccccac cagcgccgcg
    12001 atgtcacaaa ttgggcaaag ctatctcccc gccagtaccg gcttcatcat tggcgcgctt
    12061 ggcttaatgg cttttgttgg ttggcaatgg cgcggaagaa tgcgccgtca ggctttgggt
    12121 ttacagtctc cggcctctac cgcagtagtc ggtcgccagg ctttaaccgc tatcatcgta
    12181 ttaggcgcaa tctggctgtt gaatgattac cgtggcgttc ccactcctgt tctgctgctg
    12241 acgttgctgt tactcggcgg aatgtttatg gcaacgcgga cggcatttgg acgacgcatt
    12301 tatgccatcg gcggcaatct ggaagcagca cgtctctccg ggattaacgt tgaacgcacc
    12361 aaacttgccg tgttcgcgat taacggatta atggtagcca tcgccggatt aatccttagt
    12421 tctcgacttg gcgctggttc accttctgcg ggaaatatcg ccgaactgga cgcaattgca
    12481 gcatgcgtga ttggcggcac cagcctggct ggcggtgtgg gaagcgttgc cggagcagta
    12541 atgggggcat ttatcatggc ttcactggat aacggcatga gtatgatgga tgtaccgacc
    12601 ttctggcagt atatcgttaa aggtgcgatt ctgttgctgg cagtatggat ggactccgca
    12661 accaaacgcc gttcttgatt ttgattaaaa ttttctcaaa gccggttacg tattaccggt
    12721 tttgagtttt tgcatgattc agcaggaaaa gaaccatgtt tactaaacgt caccgcatca
    12781 cattactgtt caatgccaat aaagcctatg accggcaggt agtagaaggc gtaggggaat
    12841 atttacaggc gtcacaatcg gaatgggata ttttcattga agaagatttc cgcgcccgca
    12901 ttgataaaat caaggactgg ttaggagatg gcgtcattgc cgacttcgac gacaaacaga
    12961 tcgagcaagc gctggctgat gtcgacgtcc ccattgttgg ggttggcggc tcgtatcacc
    13021 ttgcagaaag ttacccaccc gttcattaca ttgccaccga taactatgcg ctggttgaaa
    13081 gcgcattttt gcatttaaaa gagaaaggcg ttaaccgctt tgctttttat ggtcttccgg
    13141 aatcaagcgg caaacgttgg gccactgagc gcgaatatgc atttcgtcag cttgtcgccg
    13201 aagaaaagta tcgcggagtg gtttatcagg ggttagaaac cgcgccagag aactggcaac
    13261 acgcgcaaaa tcggctggca gactggctac aaacgctacc accgcaaacc gggattattg
    13321 ccgttactga cgcccgagcg cggcatattc tgcaagtatg tgaacatcta catattcccg
    13381 taccggaaaa attatgcgtg attggcatcg ataacgaaga attgacccgc tatctgtcgc
    13441 gtgtcgccct ttcttcggtc gctcagggcg cgcggcaaat gggctatcag gcggcaaaac
    13501 tgttgcatcg attattagat aaagaagaaa tgccgctaca gcgaattttg gtcccaccag
    13561 ttcgcgtcat tgaacggcgc tcaacagatt atcgctcgct gaccgatccc gccgttattc
    13621 aggccatgca ttacattcgt aatcacgcct gtaaagggat taaagtggat caggtactgg
    13681 atgcggtcgg gatctcgcgc tccaatcttg agaagcgttt taaagaagag gtgggtgaaa
    13741 ccatccatgc catgattcat gccgagaagc tggagaaagc gcgcagtctg ctgatttcaa
    13801 ccaccttgtc gatcaatgag atatcgcaaa tgtgcggtta tccatcgctg caatatttct
    13861 actctgtttt taaaaaagca tatgacacaa cgccaaaaga gtatcgcgat gtaaatagcg
    13921 aggtcatgtt gtagcgatga tgagaattgt cggcgtcaca tcagggaact cagcacagcc
    13981 acctgatgcg agcaaaagcc ttatccgacc aacaaatcag ataaggctca aggaaatgca
    14041 attacatatg cgccgcgatt aaccgttggt tatcctggta cattgcgaac aggtagttat
    14101 tataactctt ccctttggtc gagtagccct tcagcttgtg aatcatcgct gtggcagtca
    14161 cttcctgatc cgctttacgc agctgcgcac gcgatttacg gaacgaagag taagccggat
    14221 gcgtattgag gttagtgaca taggcgctca ccgattcttt gacagaacta aactgtgagt
    14281 accctttcac tttacccggc gcattggtac aacgtccttt catgcatttc atgccgaaaa
    14341 gattgttgtt gttgcgcgcc agcttcgacg ttccccaacc gctttctgct gcagccatcg
    14401 tcgccaccat actggtaggg ataatgtcta cgcgttcaag caaggtattc cacgggattt
    14461 ttcgcgtatt accagaccac ttcaccttgt agcgtttggc gatgtctttc agacgcgcac
    14521 gctcagcagg tgaccattgg ccctgatact gttttgaaat cagccagtta cgttctgcag
    14581 taatggctgc attttggctg gtaatgtaag gcattacggt ccggagaaac gcctttttcc
    14641 ttggtgttcc ggaagggtat tttcgcaaat caggaagtga actactcttt gcactattgc
    14701 gagaatactc ttgtttactg cttacctgtt tattactagc tttagttaag tgggactttt
    14761 gactcgctgt tgttgtgtgc gtcttcgcta acacctcact cgaaaacacc agagtgagta
    14821 acataagaat catcgcccca tatcgtcgta tgggagtcaa aatcatcagg tctcctggtc
    14881 ggatttaatc attccaacac cttatatttt tcacaaattt gagagttgaa tctcaaatca
    14941 tatcaaaaat agctgtcaag agcaccccaa ggaatagtcc aaatctgaaa ctatgtcacg
    15001 tgttaacgat tcagattggc gctaaatcgc agaaaatgtg gggtttatcg caaaattcag
    15061 ccgttttttg cgcgagatcg ctcacccttg cttctcatcc tgtggactta ccgctcaggg
    15121 atgagttttg tctggcttat cgctggcaaa ctgtctgaaa tcgcagcaat aaggactcat
    15181 ccaccatgaa actcgccgcc tgttttctga cactccttcc tggcttcgcc gttgccgcca
    15241 gctggacttc tccggggttc cctgccttta gcgaacaggg aacgggaaca tttgtcagcc
    15301 acgcgcagtt gcccaaaggt acgcgtccac tcacgctaaa ttttgaccaa cagtgctggc
    15361 agcctgcaga tgcgataaaa ctcaatcaga tgctttccct gcaaccttgt agcaacacgc
    15421 cgcctcaatg gcgattgttc agagacggca aatatacgct gcaaatagac acccgctccg
    15481 gtacgccaac attgatgatt tccatccaga acgccgccga accggtagca aacctggtcc
    15541 gtgaatgccc gaaatgggat ggattaccgc tcacgctgga tgtcagcgcc actttcccgg
    15601 aaggagccgc cgtacgggat tattacagcc agcaaattgc gatagtgaag aacggtcaaa
    15661 taacgttaca acccgctgct accagcaacg gtttactcct gctggaacgg gcagaaactg
    15721 acgcccctgc ccctttcgac tggcataacg ccacggttta ctttgtgctg acagatcgtt
    15781 tcgaaaacgg cgatcccagt aatgaccaga gttacggacg tcataaagac ggtatggcgg
    15841 aaattggcac ttttcacggc ggcgatttac gcggcctgac caacaaactg gattacctcc
    15901 agcagttggg cgttaatgct ttatggataa gcgccccatt tgagcaaatt cacggctggg
    15961 tcggcggcgg tacaaaaggc gatttcccgc attatgccta ccacggttat tacacacagg
    16021 actggacgaa tcttgatgcc aatatgggca acgaagccga tctacggacg ctggttgata
    16081 gcgcacatca gcgcggtatt cgtattctct ttgatgtcgt gatgaaccac accggctatg
    16141 ccacgctggc ggatatgcag gagtatcagt ttggcgcgtt atatctttct ggtgacgagg
    16201 tgaaaaaaac gctgggtgaa cgctggagcg actggaaacc tgccgccggg caaacctggc
    16261 atagctttaa cgattacatt aatttcagcg acaaaacagg ctgggataaa tggtggggaa
    16321 aaaactggat cagaacggat atcggcgatt acgacaatcc tggattcgac gatctcacta
    16381 tgtcgctggc ctttttgccg gatatcaaaa ccgaatcaac taccgcttct ggtctgccgg
    16441 tgttctataa aaacaaaacg gatactcacg ctaaagtcat cgaaggcttt acacctcgcg
    16501 attacttaac ccactggtta agtcagtggg tccgcgacta tgggattgat ggttttcggg
    16561 tcgataccgc caaacatgtt gagttgcccg cctggcagca actgaaaacc gaagccagcg
    16621 ccgcgcttcg cgaatggaaa aaagctaacc ccgacaaagc attagatgac aaacctttct
    16681 ggatgaccgg tgaagcctgg ggccacggcg tgatgcaaag tgactactat cgccacggct
    16741 tcgatgcgat gatcaatttc gattatcagg agcaggcggc gaaagcagtc gattgtctgg
    16801 cgcagatgga tacgacctgg cagcaaatgg cggagaaatt gcagggtttc aacgtgttga
    16861 gctacctctc gtcgcatgat acccgtctgt tccgtgaagg gggcgacaaa gcagcagagt
    16921 tattactatt agcgccaggc gcggtacaaa tcttttatgg cgatgaatcc tcgcgtccgt
    16981 tcggtcctac aggttctgat ccgctgcaag gtacacgttc ggatatgaac tggcaggatg
    17041 ttagcggtaa atctgccgcc aacgtcgcgc actggcagaa aatcagccag ttccgcgccc
    17101 gccatcccgc aattggcgcg ggcaaacaaa cgacactttc gctgaagcag ggctacggct
    17161 ttgttcgtga gcatggcgac gataaagtgc tggtcatctg ggctgggcaa cagtgacttt
    17221 tccggcttcc cgttcgtcag tacctcggga agccgccaac caggataaaa tgtcagccct
    17281 aatcagcgtt gcaggataaa gcaccgctca ctctccaaca gaccgatttg caccccagca
    17341 aatgtagcgt tattgttacc ttccttgcta cagagttcga cagatatccc gctatgacat
    17401 tctccctttt tggtgacaaa tttacccgcc actccggcat tacgctgctg atggaagatc
    17461 tgaacgacgg tttacgcacg cctggcgcga ttatgctcgg cggcggtaat ccggcgcaga
    17521 tcccggaaat gcaggactac ttccagacgc tactgaccga catgctggaa agtggcaaag
    17581 cgactgatgc actgtgcaat tacgacggtc cacaggggaa aacggagcta ctcacactgc
    17641 ttgccggaat gctgcgcgag aagttgggtt gggatatcga agcacagaat attgcactaa
    17701 caaacggcag ccagagcgcg tttttctact tatttaatct gtttgccgga cgccgtgccg
    17761 atggtcgggt caaaaaagtg ctgttcccgc tggcaccgga atacattggc tacgctgacg
    17821 ccggactgga agaagatctg tttgtctctg cgcgtccgaa tattgaactg ctgccggaag
    17881 gccagtttaa ataccacgtc gattttgagc atctgcatat tggcgaagaa accgggatga
    17941 tttgcgtctc ccggccgacg aatccaacag gcaatgtgat tactgacgaa gagttgctga
    18001 agcttgacgc gctggcgaat caacacggca ttccgctggt gattgataac gcttatggcg
    18061 tcccgttccc gggtatcatc ttcagtgaag cgcgcccgct atggaatccg aatatcgtgc
    18121 tgtgcatgag tctttccaag ctggggctgc ctggctcccg ctgcggcatt atcatcgcca
    18181 atgaaaaaat catcactgcc atcaccaata tgaacggcat tatcagcctg gcacctggcg
    18241 gtattggtcc ggcgatgatg tgtgaaatga ttaagcgtaa cgatctgctg cgcctgtctg
    18301 aaacagtcat caaaccgttt tactaccagc gtgttcagga aactatcgcc atcattcgcc
    18361 gctatttacc ggaagatcgc tgcctaattc ataaaccaga aggagccatt ttcctctggc
    18421 tatggtttaa ggatttgccc attacgaccg agcaactcta ccagcgcctg aaagcacgcg
    18481 gcgtgctgat ggtgccgggg cacaacttct tcccagggct ggataaaccg tggccgcata
    18541 cgcatcaatg tatgcgcatg aactacgtac cagagccgga gaaaattgag gcgggggtga
    18601 agattctggc ggaagagata gaaagagcct gggctgaaag tcactaaaaa ttgcctgatg
    18661 cgctacgctt atcaggccta catgatttct gcaatatatt gaatttgcaa gaatttgtag
    18721 gccggataag gcgtttacgc cgcatctggc ataaacaaag cgcactattc cggcgttgag
    18781 aaacgccgga aaaacgtttc aaacaggctg ctgccgtagc cgatgccgct gcactttctc
    18841 gacatccatg cactgcaacg cctttgtcgg gcaggcttca acacaggccg gccccgtctc
    18901 ccgatgccag cacagatcgc acttaatcgc cctcgccttt ttgcgcgaag aaacgacctc
    18961 catcgcacca aacgggcaag ccagcataca gcttttacag ccaatacaac gtgattgttc
    19021 aacgaaaata tgcccatgtt cgcggcttat cgcgtcaaca gggcagacat tcgcgcacgg
    19081 tgcatcttca cactgatgac aggctactgc cgtggtccag ctgtggtctt taatgacacg
    19141 aatacgggaa ataaactcgt ctggtgacaa cgcagcgcaa tcctgattct cctgatgcga
    19201 cactgcgcaa gccacttcac aggtacggca accgatacat ttcgtcgcat ccgcaataat
    19261 aaaccggttc atgatcactc ctttgcacta aaacagcaga gtgccagaga gcgcgtccct
    19321 actgctttga tccaacgaag gaaatgttaa agttttggca cttgtccaaa gcgttatgtg
    19381 atcgcgccct ggtcgtccct gacagtaaat cccagttcat tagaaatagc ctgcgcggtt
    19441 tcacgcagtg gtttcaggag atttttctcc cccacctgtt tcagacgtga tgtcgaaagc
    19501 gaaatcgaca cggcgtacgg cacccgccca tgaatattaa acaccggaac agcaatacag
    19561 gagacgccga gttcgttttc ttctctgtcc atcgccgctc cgctttcacg aatgtgcgcc
    19621 agttcgtcga acatcgcggg cagctcggta atggtattgc gggttaacgg ctggatctca
    19681 tgctgatggt tttcccagta tgacttcacg tagtccgggt gaccaaacgc catgtagatc
    19741 ttgcccattg cggaacagta gagcggcata tgctggccaa tataggcacg ggttcgcagc
    19801 atcccggttg tgggttccag cttataaatc aaaatagcgt gatcgtcttc gcggctggag
    19861 aagttaatgg tttcaccagt ggcgatgttc agtgcctcaa gatgcggagc ggcgatatga
    19921 atgatattca gcgaagacag cgccttctgc ccgacggcaa taaatttggt agtcaggcgg
    19981 taactccctg cggcgggcgc ggtggtcaca tagccgcagg actgtaatcc ctgcaataag
    20041 cgatggacgg tactcttatt taaaccagcc agctccgaaa gatgcgccaa cggacaaccg
    20101 tttggatagt tgctcaaaat ctcaatcagc atcaacccgc gaaacagact ctggcttccg
    20161 gctggacgct ctttttcctg cgccatctcg ttctcttttt ttcccatcac ttctttcccc
    20221 attttgtcgc gtcctgatgg tagcgcaaag tgtgccgtag ttcacgatct cgacagataa
    20281 tttataacca cttgattttt atgtcttttg aaattcatca atcagattgc tttgttaaaa
    20341 agtgatcgat atatttgaaa tcaagtttcg catattgaaa ttttaagcca aaaaagcgat
    20401 caaaaaaaca aggaagcctg ggatgaaagt gacatttgag cagttaaaag cagcctttaa
    20461 tcgggtctta atttcacgcg gcgttgacag cgaaacggct gacgcctgtg cagagatgtt
    20521 cgcccgcacc accgaatccg gcgtttattc tcacggcgtt aatcgtttcc ctcgtttcat
    20581 tcaacaactg gaaaacggcg atatcattcc tgatgcccaa cccaaacgta taaccagcct
    20641 cggcgcaatt gaacagtggg atgcccagcg ttcgatcggc aacctgacgg cgaaaaagat
    20701 gatggatcgc gccattgaac tggctgccga tcacggtatt ggtctggtgg cacttcgtaa
    20761 tgccaaccac tggatgcgcg gcggcagcta cggctggcag gcggcggaaa aaggctatat
    20821 tggcatttgc tggaccaact ccatcgccgt aatgccgccg tggggcgcaa aagagtgtcg
    20881 cattggcact aacccgctga tcgtcgccat tccttccacg ccgatcacca tggtcgatat
    20941 gtcgatgtcg atgttctctt acggcatgtt agaagttaac cgcctggcgg gccgtcagct
    21001 cccggtcgat ggtggctttg atgatgaggg caatttgacc aaagaacctg gcgttatcga
    21061 gaagaatcgc cgcattttgc cgatgggcta ctggaaaggt tctggcatgt cgattgtgct
    21121 ggatatgatc gctactctcc tttccgacgg cgcatcggtt gccgaagtca cccaggacaa
    21181 cagcgacgaa tacggcattt cacaaatttt tattgccatt gaagtggaca agcttatcga
    21241 cggtcccacc cgcgatgcca agctgcaacg tatcatggat tacgttacta ccgctgaacg
    21301 cgctgacgaa aaccaggcca tccgcttacc cggccacgaa tttactaccc tgctggccga
    21361 aaaccgccgt aacggtatta ccgttgatga cagcgtgtgg gccaaaatcc aggcgttata
    21421 aggagataag tcatgatttt tggacatatc gcgcagccca atccgtgccg tttgcccgcc
    21481 gccattgaaa aggggctcga ttttctgcgc gctaccgatt tcaacgccct ggagccgggc
    21541 gttgtcgaaa tcgacggcaa aaatatttat gcgcaaatta tcgatttaac cacacgcgaa
    21601 gcggtggaaa accgtccgga agtgcatcgt cggtatatcg atattcagtt tctggcgtgg
    21661 ggtgaagaga aaatcggcat tgctattgat acgggaaata ataaagtcag cgaatcacta
    21721 ttagagcagc gcgatattat tttttatcat gacagtgaac atgaatcatt tatagaaatg
    21781 ataccgggca gctacgcaat tttctttccg caggatgttc accgaccagg ttgtattttg
    21841 caaacagcct ctgagatacg aaaaattgtg gttaaagtcg cattaacggc gctgaattaa
    21901 tcgaataatc gtctacgcca gaacgactgg gtaatgttat tgctctaact atattaataa
    21961 tttaggttgc tgcacatgca acttgaatta tgacagacat agcctcaagg aatagctatg
    22021 aaaaaaatac ttgaagcaat actggcgatt aatctcgccg tactttcctg tattgtgttt
    22081 ataaacatta ttttaagata tggttttcag acaagcattt tatctgtaga tgaattgtca
    22141 cgttatttat ttgtctggtt aacatttatt ggcgcgattg tggcttttat ggataacgcc
    22201 cacgttcagg tcacctttct ggtggagaaa ctctcccccg catggcaacg acgagtcgct
    22261 ctggttaccc attccttaat cttatttatt tgtggcgcac tggcctgggg cgcaacgcta
    22321 aaaacaattc aggactggag cgattattca ccgatcctcg gtttacccat cggcctgatg
    22381 tatgccgctt gtctgcccac cagcctcgtt atcgcattct ttgaactgcg tcatttatat
    22441 caactcatca cgcgtagcaa ttctctaacg tcgccaccgc aaggagctta atcatggctg
    22501 tgctgatttt tctgggctgt ctgttgggtg gtattgctat cggtttgcct attgcctggg
    22561 cactgttgtt gtgcggggcg gcgttaatgt tctggctgga catgtttgat gtccagatca
    22621 tggcacaaac gctggtgaac ggagccgata gcttctccct gctggcgatt ccgttctttg
    22681 tgctggcggg tgaaatcatg aatgcgggcg gcttgtcaaa acgcattgtt gacctgccga
    22741 tgaaactggt ggggcataaa ccaggcgggc tgggctacgt cggcgtgctg gcagctatga
    22801 ttatggcgag cctttctggt tctgccgttg cggataccgc cgccgttgcc gctctactgg
    22861 tgccgatgat gcgcagcgcc aactacccgg tcaaccgggc ggcggggctg attgcctctg
    22921 gcggcattat cgcgccaatt attccccctt ccattccgtt tattatcttc ggcgtttcca
    22981 gcggattatc catcagtaag ctgtttatgg cgggcattgc ccctggcatg atgatgggcg
    23041 caacgctgat gcttacctgg tggtggcagg ccagtcgcct taatttaccc cgccagcaaa
    23101 aagcaacgat gcaggaaatc tggcactctt ttgtctccgg tatctgggcg ctgtttcttc
    23161 cagtcatcat tattggcggg tttcgctccg gtctgtttac ccctaccgaa gccggggccg
    23221 ttgctgcttt ctatgcgctg tttgtcgcca cagttattta ccgtgaaatg accttcgcca
    23281 cactttggca tgtactcatt ggcgcggcga aaaccacctc agtggttatg tttctggtgg
    23341 cctcggcaca agtttccgcc tggctgatta ccattgctga actgccgatg atggtttctg
    23401 atttactgca accgttggtc gattcaccgc gtctgctgtt tatcgtcatt atggtggcta
    23461 tcctgattgt cggcatggtc atggatttaa cgccgacggt attaattctt accccggtat
    23521 taatgccttt agttaaagag gcaggaatcg atccgattta tttcggtgtc atgtttatca
    23581 ttaactgctc aatcggctta attacaccgc ctatcggtaa tgtacttaac gttatttcag
    23641 gggtggcaaa actcaaattc gatgatgcag tcagaggcgt tttcccttac gtcctggttt
    23701 tatattcatt attagtcgta tttgttttta ttcccgatct catcatcctc cctttgaaat
    23761 ggattaatta aaaggaaaat attatgaaat tacgctctgt aacctacgca ttattcattg
    23821 ctggcctggc tgcattcagc acatcttctc tggcggcgca atctttacgt ttcggttatg
    23881 aaacctcaca aaccgactcg caacatattg cggcgaaaaa attcaatgat ttattgcagg
    23941 agagaaccaa aggcgagctg aaattaaaat tgtttccgga tagcaccctc ggtaacgcgc
    24001 aggcgatgat cagcggcgta cgtggcggca ccatcgatat ggaaatgtcc ggctcgaata
    24061 actttgccgg gttatcacca gtgatgaact tgcttgatgt ccctttcctg ttccgcgata
    24121 ccgctcacgc gcataaaacg ctcgacggca aagtcggtga tgatctgaaa gcctcacttg
    24181 aaggtaaagg actaaaagta ctggcctact gggaaaacgg ctggcgcgat gtcaccaact
    24241 cgcgcgcacc ggttaaaacc cccgccgacc tgaaagggct gaaaattcgc accaacaata
    24301 gcccgatgaa tatcgccgca ttcaaagtct ttggcgctaa cccgatcccg atgccgtttg
    24361 ccgaagtcta taccgggctg gaaacccgca ctatcgacgc tcaggaacac ccgatcaacg
    24421 tcgtctggtc agcaaaattt ttcgaagtgc agaagtacct ttctctgacg caccacgcct
    24481 attccccgct tctggtggtg atcaacaaag cgaagtttga tggcttaagc ccggagttcc
    24541 agcaagcgct aatttcatct gcgcaggaag cgggtaacta ccagcgcaaa ctggttgccg
    24601 aagatcagca aaaaatcatc gacggcatga aagaagcggg cgtggaagtc atcaccgatc
    24661 tcgaccgcaa agcctttagc gacgcactgg gtactcaggt ccgcgacatg tttgtaaaag
    24721 atgttccgca gggtgctgat ctactgaaag ccgtggatga ggtgcaataa accatgacgc
    24781 aatactggct ggggttagat tgtggcggta gctggctgaa agccgggctg tatgaccgcg
    24841 aaggccggga ggcaggcgtg cagcgcctgc cgctgtgcgc attaagcccg cagccaggtt
    24901 gggcagagcg cgatatggca gaactgtggc aatgctgcat ggctgtcatt cgcgaactgc
    24961 ttacccattc cggcgttagc ggggaacaaa ttgtcggtat cggtatctcc gcacaaggaa
    25021 aaggcttgtt tttgctggat aaaaacaaca agccgctcgg taacgccatt ttgtcctcgg
    25081 atcgccgggc gatggaaatc gttcgtcgct ggcaggaaga tggcatcccg gaaaaactct
    25141 acccgttgac ccgacaaacc ttgtggaccg ggcatccggt gtcgctgtta cgctggctga
    25201 aagagcacga accggaacgc tacgcgcaaa ttggctgcgt gatgatgacg cacgactacc
    25261 tgcgctggtg tttaaccggc gtcaaaggct gtgaagagag caatatttcc gagtccaacc
    25321 tctacaacat gagtcttggg gaatatgacc cgtgcctcac cgactggctg gggattgctg
    25381 aaatcaatca cgccctgccg cctgttgtcg gatctgccga aatctgcggg gagatcaccg
    25441 ctcagacagc cgtactgacc ggtctgaaag cgggtacgcc cgttgtcggc ggcctgtttg
    25501 atgtggtttc caccgcactc tgcgccggga tcgaagacga atttaccctt aatgcggtga
    25561 tgggcacctg ggcggtgacc agcggcataa cccgcggttt acgtgacggt gaagcgcatc
    25621 cgtatgtcta tggtcgctac gttaacgatg gtgaatttat cgttcacgaa gccagcccca
    25681 cctcttccgg caacctcgaa tggtttaccg cacagtgggg agaaatctcg tttgatgaga
    25741 tcaaccaggc cgttgccagc ttgccgaagg ccggtggcga tctctttttc ctgccgttcc
    25801 tgtacggcag caacgccggg ctcgagatga ccagcggttt ctacgggatg caggccattc
    25861 acacccgcgc acacctgttg caggccattt atgaaggggt ggtgttcagc catatgaccc
    25921 acctcaaccg gatgcgcgaa cgttttactg atgtgcacac cctgcgcgtc actggcggcc
    25981 cggcgcactc cgatgtctgg atgcaaatgc tggcggacgt cagcggtctg cgtatcgagc
    26041 tgccgcaggt ggaagaaacc ggctgttttg gcgcggcact tgccgcccgt gtcggcaccg
    26101 gagtttatcg cgatttcagc gaagctcaac gtgacttaca gcacccggta cgcaccctgc
    26161 tgccggatat gaccgcccat cagctttacc aacaaaaata ccaacgctat cagcatctca
    26221 ttgccgcact tcagggcttt cacgcccgca tcaaggagca catattatga gccgaccact
    26281 tctgcaactg gcactcgacc actcatcact tgaagccgca cagcgcgacg tgatgcagtt
    26341 aaaagacagc gtcgatattg tcgaagcggg caccattctc tgtttaaacg aagggcttgg
    26401 cgcggtgaaa gccttgcgcg aacagtgccc tgacaaaatc atcgttgccg actggaaggt
    26461 cgccgacgct ggtgaaacgc tcgcgcaaca ggcatttggc gcaggcgcta actggatgac
    26521 catcatctgc gccgcaccgc tcgcgacggt ggaaaaaggc cacgcgatgg cgcaacgctg
    26581 cggtggtgaa attcagatcg agctgttcgg taactggacg ctggacgacg cccgcgactg
    26641 gcatcgtatt ggcgtgcggc aggcgattta tcatcgcggt cgtgatgcac aggccagcgg
    26701 gcaacagtgg ggcgaagccg atctggcacg catgaaggcg ctttccgata tcggccttga
    26761 gctttccatt accggcggga ttacccctgc tgacctgccg ctgtttaaag atattcgcgt
    26821 gaaagcgttt attgccgggc gagcactggc aggctcagca aatccggcgc aggtggctgg
    26881 cgatttccat gcgcaaatcg acgctatctg gggaggcaag cgtgcgtaat catccgttag
    26941 ggatttatga aaaggcgctg gcgaaagatc tctcctggcc ggagcggctg gtgctggcaa
    27001 aaagctgcgg ttttgatttt gtcgaaatgt cggtggatga aaccgacgaa cggctttcac
    27061 gtcttgactg gagcaccgca caaaggactt cgctggttgc cgcgatgatc gaaacgggtg
    27121 ttgggatccc gtcgatgtgc ctgtccgcac atcgtcgctt tccttttggt agccgtgacg
    27181 acgcggtacg ccagcgagca cgggagatca tgagcaaagc gattcgtctg gcacgcgatc
    27241 tcggcatacg caccatccag ctggcgggct acgacgtcta ttacgaagac cacgatgaag
    27301 gcacccggca acgttttgct gaagggctgg cgtgggcggt cgaacaggcg gcggcatcac
    27361 aagtcatgct agcggtggag attatggaca ccgcgtttat gaactccatc agtaaatgga
    27421 aaaagtggga cgagatgctc gcctcgccgt ggttcaccgt ctacccggac gttggcaacc
    27481 tcagcgcctg gggcaatgat gttcccgccg aactgaaact gggcattgac cgtatcgccg
    27541 cgatccacct gaaagacacc cagccagtta ccgagcaaag tcccggacag ttccgcgacg
    27601 tgccgtttgg cgaaggctgc gtcgatttcg ttggcatctt caaaacgctg cataaactga
    27661 actatcgcgg ttctttcctg attgagatgt ggaccgaaaa agccaaagag ccggtgctgg
    27721 agattattca ggcgcggcgt tggattgaag cgcgtatgca ggaggctgga tttatatgtt
    27781 agagcaactg aaagccgacg tgctggcggc gaatctggcg cttcccgctc accatctggt
    27841 gacgttcacc tggggcaatg tcagcgcggt agacgaaacg cggcaatgga tggtaatcaa
    27901 accttccggc gtcgagtatg acgtgatgac cgccgacgat atggtggtgg ttgagatagc
    27961 cagcggcaag gtggtggaag gtagcaaaaa gccctcgtcc gacacgccaa cgcatctggc
    28021 gctttaccgt cgctacgccg aaatcggtgg cattgtgcat acccactcac gccacgccac
    28081 catctggtcg caggccgggc tggatctccc cgcctggggc accacgcacg ctgattattt
    28141 ctatggtgcc atcccctgca cgcgacagat gaccgcagag gagattaacg gcgaatatga
    28201 atatcagacc ggcgaagtga tcattgaaac cttcgaagaa cgtggcagga gtccggcaca
    28261 aatcccggcg gtgctggtgc attctcatgg cccgttcgca tggggtaaaa acgccgccga
    28321 tgccgtgcat aacgccgtag tactcgaaga atgcgcctat atgggcctat tctcgcgcca
    28381 gcttgcgccg cagctccctg cgatgcaaaa cgaactgctg gataagcact acctgcgtaa
    28441 gcatggggcc aatgcctatt acgggcagta atccctcacg ccggggcttc atcgccccgg
    28501 cactacgaat tgatatgttc cttgctgtaa cgccgcttcc acgctgctgg cgttaaaccg
    28561 gtgtgcttgc gaaaaatctg ccggaaatag ccaacgtcat taaacccgca caacgcagcc
    28621 acttcagtga gcgatcgcgc ttcgctaatt aacagctttt cggcttcgcg cactcgctgg
    28681 cgatggattg cttctgttaa cgtcagatga aacacccgcc ggtagacgcg cccaagataa
    28741 tcggcattgc agtacagctc gcgggctaaa agcgccgtgg aaagcgggcg atgatattgc
    28801 gtgcggatca gtttctgcgc tttccaggca agggtggtgc ctgcgccatc ggcctgttca
    28861 tcaagacgcg cgtcacgggt gagctgctgc aaaatcagca gcacaataaa ctccagcgcc
    28921 ggagtgcgtt gatgcttttc ctgttcgctt aagaactggc gaaacagggc caccagcgcc
    28981 tgcggatcga caaccttcgt ttgttgcggc acgctaagat gagtaagcca gcgagggtcg
    29041 ctatccggcg ctttaacctc aaaatgcagc cagtaaaatt tgagatcggc gggaaaatcc
    29101 tccaccccaa catgttgtcg attcggccag agtaataaac tctctcccgc atcgaccaga
    29161 aatatccgtt cttcttcctg aatcgttaat cgaccttttt cgacaaagat aatttcccat
    29221 gactccagcc gccttgcagg atgcctccct acgccgcggg aaataaataa tccaccattt
    29281 tgcactttaa tcggtaacgt catggataat tcgagcattg atatgtaatt tcccgcttat
    29341 tcattaatga ttaaacacat taccttttga ttattaatca aaaacattaa tttcacctga
    29401 tccatttcac acttttaaat tcaggtcgga atcgtcacct ttttttactc ttttctcacc
    29461 ttgttgatat tcccgttcac ggcagaatta atcaggtcat tgcaataaaa ctaaaaattg
    29521 cttcctattc acgaggaata tctatgacct ctacaccgat tactaccgct gatatcgcta
    29581 aaggtaaaat tgacgatgcg ttatctgtac gggaaaaaat aggctacggc ctgggtgacg
    29641 ctggcggcac cgtaataact tgcctgatca tgaactttct cacctttttc tacaccgacg
    29701 tttttggatt aactccggcg ctggttggca cgctgtttat tgcactgcgc gtgtttgatg
    29761 ccatctccga cccggtgatg ggcgtcattg ccgaccggac gcaaagtcgc tgggggcgct
    29821 ttcgtccgtg gcagttatgg attgccattc ccatcggcat tatcggcatc ctgacgttca
    29881 ccgtgccaga tgccagcatg ggagtaaaaa tcacctgggc gttcggcact tacctgctcc
    29941 tttcagtcgg ttataccgcc atcaacgtac cgtactgcgc gctgatcaac accatgacca
    30001 cccgccacaa tgaagtgatc tcctgccagt cctggcgatt cgttctctgc ggcgtagcgg
    30061 gatttctggt ttcggtaggc ttaccgtgga tggtagatct cttcggtcag ggcaacgctg
    30121 cacgcggcta tcaactgggc gtcggcgtat tgtgcgccat tgccgtggtg atgttcctgt
    30181 gctgtttttt ctgggttcgt gaacgggtgc cgctctccac aatggggaaa tttaccctgc
    30241 gcgaacatct tgccgggctg cggaacaacg accaactgct gctgatgctg gtcatgtctt
    30301 tcctgctgat taacgtcttt aatattcgcg gcggtgggta tatgtacttc attacctacg
    30361 tcttacaagg cagtacgggc tacacgtcgc tgttcttcac catggtcacc ttcgcctcca
    30421 ttatcggctc ggtgattgtc agcccgttaa cgcggcgttt cgataccgtc aaaatttatt
    30481 actacaccaa cctgctcctc gctgcactgg cggtgttgat gtggttcctg ccctccggcc
    30541 cggcttatca aacgctgtgg ctggcggtga tcctcggtaa tggcgtgatt cttggcttca
    30601 cattgccatt gcacttctca ttgatggcct ttgccgatga ctacggcgag tggaaaaccc
    30661 gcgtacgttc ttccggcatg aacttcgcct tcaatctgtt tttcatcaag ctagcctggg
    30721 cctccagcgc cgggatcatc agcctgctgt ttatttttgt cgcctaccag cctggcgtgg
    30781 aaaaccagac cgccagttcg cttggcggga tcacggcgat ggaaacattg ctgcctgcgc
    30841 tattccacct gctgctggca ggggcgatcc gcttttgcaa actcaataat cctatgatgt
    30901 cgcgcatagc taccgacctg cgtcagcgtc atgtacagcc ttaaggagca caagatgaac
    30961 atttcggaag tcgatctgcg taaactgacg gtcagcgatc cgttcctcgg tcagtaccaa
    31021 caactggtcc gcgacgtggt gatttcttat cagtgggatg ccttgaacga tcgtatccca
    31081 gaagcggaac ccagccatgc gattgaaaac tttcgcattg ccgccggact tcaggagggt
    31141 gaattttacg ggatggtgtt tcaggacagc gacgtcgcca aatggctgga agcggtagcc
    31201 tggtcgctgt gccagaagcc ggacgccgaa ctggaaaaaa ccgccgacga ggtaatcgaa
    31261 ctgatcgcct ccgcccaatg cgaagacggc tatctcaata cttactttac ggtaaaagca
    31321 cccgaagaac gctggagcaa tcttgcggag tgtcatgaac tttactgcgc cggtcatctg
    31381 attgaagccg gagtcgcctt cttccaggcc acgggaaaac gacgcttgct ggaggtggtt
    31441 tgccgtctgg ccgatcatat cgaccgcgta tttggtccag atgaagacaa gctgcagggt
    31501 tatcccggtc atccggaaat tgaactggcg ctgatgcgtc tctacgaagt caccgaagag
    31561 ccgcgctacc tggcgctgac gaactatttt gtcgaacagc gtggtgtgca accgcactat
    31621 tacgaccagg aatatgaaaa gcgcgggcag acctcgcact ggcacaccta cggcccggcg
    31681 tggatggtga aagacaaagc ctacagccag gcacatttgc cccttgcgca acagcaaacc
    31741 gccatcggtc acgcggtacg ttttgtctat ctgatgaccg gcgtcgcgca tctcgcgcgt
    31801 ttaagtcacg atgacagcaa gcgtcaggac tgcctgcggc tgtggaacaa tatggcccag
    31861 cgtcagttat atattaccgg cggcattggc tcacagagca gcggtgaagc gttcagcagc
    31921 gattacgatc tgccgaatga cacggtatac gctgaaagtt gcgcctccat cggcctgatg
    31981 atgtttgccc gacgaatgct ggaaatggaa ggcgacagtc aatatgccga tgtgatggag
    32041 cgcgcactgt acaacaccgt gctcggcggc atggcgctgg acggcaaaca tttcttctat
    32101 gtgaatccgc tggaagtaca tccaaaatcg ctgaaattca accatatcta cgatcacgtt
    32161 aaaccgatcc gccagcgttg gtttggctgc gcttgttgtc cgccaaatat cgcccgcgtg
    32221 ctgacctcga ttggtcatta tctctacacg ccgcgtgaag atgcgttgta tatcaacata
    32281 tacgcaggaa acagcatgga agtgccggta gaaaatggca cactgcgcct gcgggttagc
    32341 gggaactatc cgtggcagga gcaggtgaca attgcggtcg aatcgcccca gccggtgcgt
    32401 catacgctgg ctttacgtct gccggactgg tgcacacagc cgcagatcat attgaatggg
    32461 gaagaggtcg agcaggatat tcgtaaaggg tatttgcaca ttacccgcga atggcaggag
    32521 ggcgatacgc tgaatctgac tttgccgatg ccggtacgcc gcgtttacgg taacccgctg
    32581 gtgcgtcacg tcgccggaaa agtggcgatt cagcgcggcc cgctggtgta ttgcctggaa
    32641 caggccgaca acggcgagtc actgcataat ctgtggctgc ccaccgatgc gccatttacg
    32701 acatttgaag gcaagggatt gtttagccat aagatcttaa tccaggcacc gggttaccgg
    32761 tatgaacaga gcaatccaga gcagcaaccg ctgtggcatt acgacagcgc gccagccaaa
    32821 cgccagccgc aaactctgac ctttatcccg tggtttagct gggctaaccg gggcgaaggc
    32881 gaaatgcgga tctgggtgaa tgaggaaaag catcgccatc cggaggttgg ataaggcgct
    32941 cgcgccgcat ccaacgtagg gagcacattg cctgatgcga cgcttaacac gtcttatcag
    33001 gcatacgagt cggtgcgaga gcgtaggcca gccgcaccga catccaccgg tgaattaaaa
    33061 acgccagctc acgccggtga caaaggtaaa actctcatta cgatcaatca tcgggctgtt
    33121 ggtaatctct tccggcagct cgctgtatcc tgcgctcgcc atcaatacga cgtgctctcc
    33181 tatcgggtat tttgccgtca ggctgacata gggcacccag gcatcctgcg cggaataact
    33241 tgccagaccg ctacgacggg actcactctc tgaaatgcca tagtaatagt cactgaaatt
    33301 ctcgtcataa tagagaacgc ccagcgcagg tgtcagcgac aggcgaccta tctgcatttt
    33361 gtggaatacc gatagctccc ccacccagcc gttgctgtta tccagaacgt ccgcagccgc
    33421 agaggctttc acagttcccc aacgctcgtg gtgataccag gcaacccccg ccatagccgt
    33481 actatcacgc ttatcaagct gttgcatggc ataatcgtca ttatcggcag ggtcaaattc
    33541 cagcggcatc caggatgcgg tcaggctaag ttcatttttt tcactttgcg acagaataaa
    33601 acctaacgtg gtctgacgaa cataaaaaga atcaccttca taactaatca ggggaattgc
    33661 ctttgtattt tcattataac cgcgataagg cgattcatta taagccgcac cggcaccaat
    33721 ggataattca gaagcagttg cgcttgccat aaaaggcaac gcaaataacg ccacaatatt
    33781 gcggttaatt aacatgttcg gtattccatt ttaaaataag ataaaaaaga gtcggcatag
    33841 taatgcttac aattt
//
LOCUS       DAPGUL010000043        33701 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.043, whole genome shotgun sequence.
ACCESSION   DAPGUL010000043 DAPGUL010000000
VERSION     DAPGUL010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33701
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.043"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            192..371
                     /locus_tag="RHX21_002201"
     CDS             192..371
                     /locus_tag="RHX21_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309858.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein"
                     /protein_id="HDV1987376.1"
                     /translation="MAEHRGGSGNFAEDREKASDAGRKGGQHSGGNFKNDPQRASEAG
                     KKGGQQSGGNKSGKS"
     gene            457..957
                     /locus_tag="RHX21_002202"
     CDS             457..957
                     /locus_tag="RHX21_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HDV1987377.1"
                     /translation="MNMKTIEDVFIHLLSDTYSAEKQLTRALAKLARATSNEKLSQAF
                     HAHLEETHGQIERIDQVVESESNLKIKRMKCVAMEGLIEEANEVIESTEKNEVRDAAL
                     IAAAQKVEHYEIASYGTLATLAEQLGYRKAAKLLKETLEEEKATDIKLTDLALNNVNK
                     KAENKA"
     gene            1003..1509
                     /locus_tag="RHX21_002203"
     CDS             1003..1509
                     /locus_tag="RHX21_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HDV1987378.1"
                     /translation="MNRIEHYHDWLRDAHAMEKQAESMLESMASRIDNYPELRARIEQ
                     HLSETKNQIVQLETILDRNDISRSVIKDSMSKMAALGQSIGGIFPSDEIVKGSISGYV
                     FEQFEIACYTSLLAAAKNAGDTVSIPIIEAILNEEKQMADWLIQHIPQTTEKFLIRSE
                     TDGVEAKK"
     gene            complement(1569..2207)
                     /gene="ompW"
                     /locus_tag="RHX21_002204"
     CDS             complement(1569..2207)
                     /gene="ompW"
                     /locus_tag="RHX21_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpW"
                     /protein_id="HDV1987379.1"
                     /translation="MKKLTVAALAVTTLLSGSAFAHEAGEFFMRAGSATVRPTEGAGG
                     TLGSLGGFSVTNNTQLGLTFTYMATDNIGVELLAATPFRHKIGTRATGDIATVHHLPP
                     TLMAQWYFGDASSKFRPYVGAGINYTTFFDNGFNDHGKEAGLSDLSLKDSWGAAGQVG
                     VDYLINRDWLVNMSVWYMDIDTTANYKLGGAQQHDSVRLDPWVFMFSAGYRF"
     gene            2447..2536
                     /locus_tag="RHX21_002205"
                     /pseudo
     CDS             2447..2536
                     /locus_tag="RHX21_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460692.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
     gene            2564..3307
                     /locus_tag="RHX21_002206"
     CDS             2564..3307
                     /locus_tag="RHX21_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0259 family protein"
                     /protein_id="HDV1987380.1"
                     /translation="MSITAQSVYRDTGNFFRNQFMTILLVSLLCAFITVVLGHVFSPS
                     DAQLAQLNDGVPVSGSSGLFDLVQNMSPEQQQILLQASAASTFSGLIGNAILAGGVIL
                     IIQLVSAGQRVSALRAIGASAPILPKLFILIFLTTLLVQIGIMLVVVPGIIMAILLAL
                     APVMLVQDKMGIFASMRSSMRLTWANMRLVAPAVLSWLLAKTLLLLFASSFAALTPEI
                     GAVLANTLSNLISAILLIYLFRLYMLIRQ"
     gene            3337..3876
                     /locus_tag="RHX21_002207"
     CDS             3337..3876
                     /locus_tag="RHX21_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation protein A"
                     /protein_id="HDV1987381.1"
                     /translation="MKQFLDFLPLVVFFAFYKIYDIYAATAALIVATAIVLIYSWVRF
                     RKVEKMALITFVLVVVFGGLTLFFHNDEFIKWKVTVIYALFAGALLVSQWVMKKPLIQ
                     RMLGKELTLPQPVWSKLNLAWAVFFILCGLANIYIAFWLPQNIWVNFKVFGLTALTLI
                     FTLLSGIYIYRHMPQEDKS"
     gene            3981..4379
                     /gene="yciA"
                     /locus_tag="RHX21_002208"
     CDS             3981..4379
                     /gene="yciA"
                     /locus_tag="RHX21_002208"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioester hydrolase YciA"
                     /protein_id="HDV1987382.1"
                     /translation="MSTTHNVPQGDLVLRTLAMPADTNANGDIFGGWLMSQMDIGGAI
                     LAKEIAHGRVVTVRVEGMTFLRPVAVGDVVCCYARCVQKGTTSVSINIEVWVKKVASE
                     PIGQRYKATEALFKYVAVDPEGKPRALPVE"
     gene            complement(4419..5138)
                     /gene="tonB"
                     /locus_tag="RHX21_002209"
     CDS             complement(4419..5138)
                     /gene="tonB"
                     /locus_tag="RHX21_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB system transport protein TonB"
                     /protein_id="HDV1987383.1"
                     /translation="MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQP
                     ISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKP
                     VKKVQEQPKRDIKPVESRPASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQ
                     PQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPG
                     KPGSGIVVNILFKINGTTEIQ"
     gene            5362..5658
                     /locus_tag="RHX21_002210"
     CDS             5362..5658
                     /locus_tag="RHX21_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415767.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciI family protein"
                     /protein_id="HDV1987384.1"
                     /translation="MLYVIYAQDKADSLEKRLSVRPAHLARLQLLHDEGRLLTAGPMP
                     AVDSNDPGAAGFTGSTVIAEFESLEAAQAWADADPYVAAGVYEHVSVKPFKKVF"
     gene            5957..7210
                     /gene="kch"
                     /locus_tag="RHX21_002211"
     CDS             5957..7210
                     /gene="kch"
                     /locus_tag="RHX21_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated potassium channel protein"
                     /protein_id="HDV1987385.1"
                     /translation="MSHWATFKQTATNLWVTLRHDILALAVFLNGLLIFKTIYGMSVN
                     LLDIFHIKAFSELDLSLLANAPLFMLGVFLVLNSIGLLFRAKLAWAISIILLLIALIY
                     TLHFYPWLKFSIGFCIFTLVFLLILRKDFSHSSAAAGTIFAFISFTTLLFYSTYGALY
                     LSEGFNPRIESLMTAFYFSIETMSTVGYGDIVPVSESARLFTISVIISGITVFATSMT
                     SIFGPLIRGGFNKLVKGNNHTMHRKDHFIVCGHSILAINTILQLNQRGQNVTVISNLP
                     EDDIKQLEQRLGDNADVIPGDSNDSSVLKKAGIDRCRAILALSDNDADNAFVVLSAKD
                     MSSDVKTVLAVSDSKNLNKIKMVHPDIILSPQLFGSEILARVLNGEEINNDMLVSMLL
                     NSGHGIFSDNDEQETKADSKESVQK"
     gene            complement(7265..7438)
                     /locus_tag="RHX21_002212"
     CDS             complement(7265..7438)
                     /locus_tag="RHX21_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciY family protein"
                     /protein_id="HDV1987386.1"
                     /translation="MKRSRTEVGRWRMQRQASRRKSRWLEGQSRRNMRIHSIRKCILN
                     KQRNSLLFAIYNI"
     gene            7581..9041
                     /gene="cls"
                     /locus_tag="RHX21_002213"
     CDS             7581..9041
                     /gene="cls"
                     /locus_tag="RHX21_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDV1987387.1"
                     /translation="MTTVYTLVSWLAILGYWLLIAGVTLRILMKRRAVPSAMAWLLII
                     YILPLVGIIAYLAVGELHLGKRRAERARAMWPSTAKWLNDLKACKHIFAEENSSVAAP
                     LFKLCERRQGIAGVKGNQLQLMTESDDVMQALIRDIQLARHNIEMVFYIWQPGGMADQ
                     VAESLMAAARRGIHCRLMLDSAGSVAFFRSPWPELMRNAGIEVVEALKVNLMRVFLRR
                     MDLRQHRKMIMIDNYIAYTGSMNMVDPRYFKQDAGVGQWIDLMARMEGPIATAMGIIY
                     SCDWEIETGKRILPPPPDVNIMPFEQASGHTIHTIASGPGFPEDLIHQALLTAAYSAR
                     EYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSMLVGWASRAFFTELLAAG
                     VKIYQFEGGLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLAIDDKGFGADLAAVQ
                     DDYISRSRLLDARLWLKRPLWQRVAERLFYFFSPLL"
     gene            9076..9405
                     /locus_tag="RHX21_002214"
     CDS             9076..9405
                     /locus_tag="RHX21_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309775.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciU family protein"
                     /protein_id="HDV1987388.1"
                     /translation="MDMDLNNRLTEDETLEQAYDIFLELAADNLDPADVLLFNLQFEE
                     RGGAELFDPAEDWQEHVDFDLNPDFFAEVVIGLADSEDGEINDVFARILLCREKDHKL
                     CHIIWRE"
     gene            complement(9458..10462)
                     /gene="oppF"
                     /locus_tag="RHX21_002215"
     CDS             complement(9458..10462)
                     /gene="oppF"
                     /locus_tag="RHX21_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide/oligopeptide ABC transporter
                     ATP binding protein OppF"
                     /protein_id="HDV1987389.1"
                     /translation="MNAVTEGRKVLLEIADLKVHFEIKDGKQWFWQPPKTLKAVDGVT
                     LRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGHVAWLGKELLGMKPDEWRAVRSD
                     IQMIFQDPLASLNPRMTIGEIIAEPLRTYHPKMSRQEVRERVKAMMLKVGLLPNLINR
                     YPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSL
                     IFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNPLHPYTRALMSAVPIPDPDLE
                     KNKTIQLLEGELPSPINPPSGCVFRTRCPIAGPECAKTRPVLEGSFRHAVSCLKVDPL
                     "
     gene            complement(10459..11472)
                     /gene="oppD"
                     /locus_tag="RHX21_002216"
     CDS             complement(10459..11472)
                     /gene="oppD"
                     /locus_tag="RHX21_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide/oligopeptide ABC transporter
                     ATP binding protein OppD"
                     /protein_id="HDV1987390.1"
                     /translation="MSVIETATVPLAQQQADALLNVKDLRVTFSTPDGDVTAVNDLNF
                     SLRAGETLGIVGESGSGKSQTAFALMGLLAANGRIGGSATFNGREILNLPEHELNKLR
                     AEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKNMSKAEAFEESVRMLDAVKMPEARK
                     RMKMYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREF
                     NTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDVFYQPVHPYSIGLLNAVPRLD
                     AEGETMLTIPGNPPNLLRLPKGCPFQPRCPHAMEICSSAPPLEEFTPGRLRACFKPVE
                     ELL"
     gene            complement(11484..12392)
                     /gene="oppC"
                     /locus_tag="RHX21_002217"
     CDS             complement(11484..12392)
                     /gene="oppC"
                     /locus_tag="RHX21_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HDV1987391.1"
                     /translation="MMLSKKNSETLENFSEKLEVEGRSLWQDARRRFMHNRAAVASLI
                     VLVLIALFVILAPMLSQFAYDDTDWAMMSSAPDMESGHYFGTDSSGRDLLVRVAIGGR
                     ISLMVGVAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFF
                     GQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTSGIVIRHIVPNV
                     LGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPA
                     GFLVVTLFCFNFIGDGLRDALDPKDR"
     gene            complement(12407..13327)
                     /gene="oppB"
                     /locus_tag="RHX21_002218"
     CDS             complement(12407..13327)
                     /gene="oppB"
                     /locus_tag="RHX21_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppB"
                     /protein_id="HDV1987392.1"
                     /translation="MLKFILRRCLEAIPTLFILITISFFMMRLAPGSPFTGERTLPPE
                     VMANIEAKYHLNDPIMTQYFSYLKQLAHGDFGPSFKYKDYSVNDLVASSFPVSAKLGA
                     AAFFLAVILGVSAGVIAALKQNTKWDYTVMGLAMTGVVIPSFVVAPLLVMIFAIILHW
                     LPGGGWNGGALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRR
                     IILRHALKPALLPVLSYMGPAFVGIITGSMVIETIYGLPGIGQLFVNGALNRDYSLVL
                     SLTILVGALTILFNAIVDVLYAVIDPKIRY"
     gene            complement(13413..15044)
                     /gene="oppA"
                     /locus_tag="RHX21_002219"
     CDS             complement(13413..15044)
                     /gene="oppA"
                     /locus_tag="RHX21_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707150.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein OppA"
                     /protein_id="HDV1987393.1"
                     /translation="MTNITKRSLVAAGVLAALMAGNVALAADVPAGVTLAEKQTLVRN
                     NGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWDNKDAKVWTFHL
                     RKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDL
                     GVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAYT
                     LKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTYNNMPI
                     ELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKA
                     QGDMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLTINLLYN
                     TSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADYNEPT
                     SFLNTMLSNSSMNTAHYKSPAFDSIMAETLKVTDEAQRTALYTKAEQQLDKDSAIVPV
                     YYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH"
     gene            15328..15624
                     /locus_tag="RHX21_002220"
     CDS             15328..15624
                     /locus_tag="RHX21_002220"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987394.1"
                     /translation="MRFLLANTFCKIVKQFSFIDRIRIYSLHPCLNKHLSIQSNRDWL
                     SMSIFSDYSSSSEMHNNLTIDYYLALSSTKGSGITNIISIILQQAQDYDVAKIT"
     gene            complement(15781..16428)
                     /gene="ychE"
                     /locus_tag="RHX21_002221"
     CDS             complement(15781..16428)
                     /gene="ychE"
                     /locus_tag="RHX21_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter YchE"
                     /protein_id="HDV1987395.1"
                     /translation="MIQTFFDFPVYFKFFIGLFALVNPVGIIPVFISMTSYQTAAARN
                     KTNLTANLSVAIILWISLFLGDTILQLFGISIDSFRIAGGILVVTIAMSMISGKLGED
                     KQNKQEKSETAVRESIGVVPLALPLMAGPGAISSTIVWGTRYHSISYLFGFFVAIALF
                     ALCCWGLFRMAPWLVRVLRQTGINVITRIMGLLLMALGIEFIVTGIKGIFPGLLN"
     gene            16905..19580
                     /gene="adhE"
                     /locus_tag="RHX21_002222"
                     /gene_synonym="adhC"
     CDS             16905..19580
                     /gene="adhE"
                     /locus_tag="RHX21_002222"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDV1987396.1"
                     /translation="MAVTNVAELNALVERVKKAQREYASFTQEQVDKIFRAAALAAAD
                     ARIPLAKMAVAESGMGIVEDKVIKNHFASEYIYNAYKDEKTCGVLSEDDTFGTITIAE
                     PIGIICGIVPTTNPTSTAIFKSLISLKTRNAIIFSPHPRAKDATNKAADIVLQAAIAA
                     GAPKDLIGWIDQPSVELSNALMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTP
                     VVIDETADIKRAVASVLMSKTFDNGVICASEQSVVVVDSVYDAVRERFATHGGYLLQG
                     KELKAVQDVILKNGALNAAIVGQPAYKIAELAGFSVPENTKILIGEVTVVDESEPFAH
                     EKLSPTLAMYRAKDFEDAVEKAEKLVAMGGIGHTSCLYTDQDNQPARVSYFGQKMKTA
                     RILINTPASQGGIGDLYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAEN
                     MLWHKLPKSIYFRRGSLPIALDEVITDGHKRALIVTDRFLFNNGYADQITSVLKAAGV
                     ETEVFFEVEADPTLSIVRKGAELANSFKPDVIIALGGGSPMDAAKIMWVMYEHPETHF
                     EELALRFMDIRKRIYKFPKMGVKAKMIAVTTTSGTGSEVTPFAVVTDDATGQKYPLAD
                     YALTPDMAIVDANLVMDMPKSLCAFGGLDAVTHAMEAYVSVLASEFSDGQALQALKLL
                     KEYLPASYHEGSKNPVARERVHSAATIAGIAFANAFLGVCHSMAHKLGSQFHIPHGLA
                     NALLICNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAAKIEKL
                     LAWLETLKAELGIPKSIREAGVQEADFLANVDKLSEDAFDDQCTGANPRYPLISELKQ
                     ILLDTYYGRDYVEGETAAKKEAAPAKAEKKAKKSA"
     gene            complement(19882..20499)
                     /gene="tdk"
                     /locus_tag="RHX21_002223"
     CDS             complement(19882..20499)
                     /gene="tdk"
                     /locus_tag="RHX21_002223"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HDV1987397.1"
                     /translation="MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRF
                     GAGKVSSRIGLSSPAKLFNQNSSLFDEIRAEHEQQAIHCVLVDECQFLTRQQVYELSE
                     VVDQLDIPVLCYGLRTDFRGELFIGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQA
                     GRPYNEGEQVVIGGNERYISVCRKHYKEALQVGSLTAIQERHRHD"
     gene            21104..21517
                     /gene="hns"
                     /locus_tag="RHX21_002224"
     CDS             21104..21517
                     /gene="hns"
                     /locus_tag="RHX21_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator H-NS"
                     /protein_id="HDV1987398.1"
                     /translation="MSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEE
                     SAAAAEVEERTRKLQQYREMLIADGIDPNELLNSLAAVKSGTKAKRAQRPAKYSYVDE
                     NGETKTWTGQGRTPAVIKKAMDEQGKSLDDFLIKQ"
     gene            complement(21661..22569)
                     /gene="galU"
                     /locus_tag="RHX21_002225"
     CDS             complement(21661..22569)
                     /gene="galU"
                     /locus_tag="RHX21_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDV1987399.1"
                     /translation="MAAINTKVKKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQY
                     VVNECIAAGITEIVLVTHSSKNSIENHFDTSFELEAMLEKRVKRQLLDEVQSICPPHV
                     TIMQVRQGLAKGLGHAVLCAHPVVGDEPVAVILPDVILDEYESDLSQDNLAEMIRRFD
                     ETGHSQIMVEPVADVTAYGVVDCKGVELAPGESVPMVGVVEKPKADVAPSNLAIVGRY
                     VLSADIWPLLAKTPPGAGDEIQLTDAIDMLIEKETVEAYHMKGKSHDCGNKLGYMQAF
                     VEYGIRHNTLGTEFKAWLEEEMGIKK"
     gene            complement(22771..23784)
                     /gene="rssB"
                     /locus_tag="RHX21_002226"
     CDS             complement(22771..23784)
                     /gene="rssB"
                     /locus_tag="RHX21_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RssB"
                     /protein_id="HDV1987400.1"
                     /translation="MTQPLVGKQILIVEDEPVFRSLLDSWFSSLGATTVLAADGVDAL
                     ELLGGFTPDLMICDIAMPRMNGLKLLEHIRNRGDQTPVLVISATENMADIAKALRLGV
                     EDVLLKPVKDLNRLREMVFACLYPSMFNSRVEEEERLFRDWDAMVDNPAAAAKLLQEL
                     QPPVQQVISHCRVNYRQLVAADKPGLVLDIAALSENDLAFYCLDVTRAGHNGVLAALL
                     LRALFNGLLQEQLAHQNQRLPELGALLKQVNHLLRQANLPGQFPLLVGYYHRELKNLI
                     LVSAGLNATLNTGEHQVQISNGVPLGTLGNAYLNQLSQRCDAWQCQIWGTGGRLRLML
                     SAE"
     gene            complement(23876..24781)
                     /gene="rssA"
                     /locus_tag="RHX21_002227"
     CDS             complement(23876..24781)
                     /gene="rssA"
                     /locus_tag="RHX21_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase RssA"
                     /protein_id="HDV1987401.1"
                     /translation="MRKIKIGLALGSGAARGWSHIGVINALKKVGIEIDIVAGCSIGS
                     LVGAAYACDRLSALEDWVTSFSYWDVLRLMDLSWQRGGLLRGERVFNQYREIMPETEI
                     ENCSRRFAAVATNLSTGRELWFTEGDLHLAIRASCSIPGLMAPVAHNGYWLVDGAVVN
                     PIPISLTRALGADIVIAVDLQHDAHLMQQDLLSFNVSEENSENGDSLPWHARLKERLG
                     SITTRRAVTAPTATEIMTTSIQVLENRLKRNRMAGDPPDILIQPVCPQISTLDFHRAH
                     AAIAAGQLAVEKKMDELLPLVRTNI"
     gene            24894..25352
                     /locus_tag="RHX21_002228"
     CDS             24894..25352
                     /locus_tag="RHX21_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YchJ family protein"
                     /protein_id="HDV1987402.1"
                     /translation="MSQLCPCGSAVEYSLCCHPYVSGEKVAPDPEHLMRSRYCAFVMQ
                     DADYLIKTWHPSCGAAALRAELMAGFAHTEWLGLTVFEHCWQDADNIGFVSFVARFTE
                     GGKTGAIVERSRFLKENGQWYYIDGTRPQFGRNDPCPCGSGKKFKKCCGQ"
     gene            25402..26244
                     /gene="purU"
                     /locus_tag="RHX21_002229"
     CDS             25402..26244
                     /gene="purU"
                     /locus_tag="RHX21_002229"
                     /EC_number="3.5.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formyltetrahydrofolate deformylase"
                     /protein_id="HDV1987403.1"
                     /translation="MHSLQRKVLRTICPDQKGLIARITNICYKHELNIVQNNEFVDHR
                     TGRFFMRTELEGIFNDSTLLADLDSALPEGSVRELNPAGRRRIVILVTKEAHCLGDLL
                     MKANYGGLDVEIAAVIGNHDTLRSLVERFDIPFELVSHEGLSRNEHDQKMADAIDAYQ
                     PDYVVLAKYMRVLTPEFVARFPNKIINIHHSFLPAFIGARPYHQAYERGVKIIGATAH
                     YVNDNLDEGPIIMQDVIHVDHTYTAEDMMRAGRDVEKNVLSRALYKVLAQRVFVYGNR
                     TIIL"
     gene            26404..26488
                     /locus_tag="RHX21_002230"
     tRNA            26404..26488
                     /locus_tag="RHX21_002230"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:26438..26440,aa:Tyr,seq:gta)
     gene            26535..26666
                     /locus_tag="RHX21_002231"
     ncRNA           26535..26666
                     /ncRNA_class="other"
                     /locus_tag="RHX21_002231"
                     /product="RtT sRNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00391"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="rtT sRNA, processed from tyrT transcript; Derived
                     by automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00391"
     gene            complement(26850..27527)
                     /gene="narI"
                     /locus_tag="RHX21_002232"
     CDS             complement(26850..27527)
                     /gene="narI"
                     /locus_tag="RHX21_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase subunit gamma"
                     /protein_id="HDV1987404.1"
                     /translation="MQFLNMFFFDIYPYIAGAVFLIGSWLRYDYGQYTWRAASSQMLD
                     RKGMNLASNLFHIGILGIFVGHFFGMLTPHWMYEAWLPIEVKQKMAMFAGGASGVLCL
                     IGGVLLLKRRLFSPRVRATTTGADILILSLLVIQCALGLLTIPFSAQHMDGSEMMKLV
                     GWAQSVVTFHGGASQHLDGVAFIFRLHLVLGMTLFLLFPFSRLVHIWSVPVEYLTRKY
                     QLVRARH"
     gene            complement(27527..28237)
                     /gene="narJ"
                     /locus_tag="RHX21_002233"
     CDS             complement(27527..28237)
                     /gene="narJ"
                     /locus_tag="RHX21_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HDV1987405.1"
                     /translation="MIELVIVSRLLEYPDAALWQHQQEMFEAIAASKNLSKEDAHALG
                     IFLRDLTAMDPLDAQAQYSELFDRGRATSLLLFEHVHGESRDRGQAMVDLLAQYEQHG
                     LQLNSRELPDHLPLYLEYLSQLPQSEAVEGLKDIAPILALLSARLQQRESRYAVMFDL
                     LLKLANTAIDSDKVAEKIADEARDDTPQALDAVWEEEQVKFFADKGCGDSAITAHQRR
                     FAGAVAPQYLNITTGGQH"
     gene            complement(28234..29772)
                     /gene="narH"
                     /locus_tag="RHX21_002234"
     CDS             complement(28234..29772)
                     /gene="narH"
                     /locus_tag="RHX21_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HDV1987406.1"
                     /translation="MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTSREGVEYAWFNNV
                     ETKPGQGFPTDWENQEKYKGGWIRKINGKLQPRMGNRAMLLGKIFANPHLPGIDDYYE
                     PFDFDYQNLHTAPEGSKSQPIARPRSLITGERMAKIEKGPNWEDDLGGEFDKLAKDKN
                     FDNIQKAMYSQFENTFMMYLPRLCEHCLNPACVATCPSGAIYKREEDGIVLIDQDKCR
                     GWRMCITGCPYKKIYFNWKSGKSEKCIFCYPRIEAGQPTVCSETCVGRIRYLGVLLYD
                     ADAIERAASTENEKDLYQRQLEVFLDPNDPKVIEQAIKDGIPLSVIEAAQQSPVYKMA
                     MEWKLALPLHPEYRTLPMVWYVPPLSPIQSAADAGELGSNGILPDVESLRIPVQYLAN
                     LLTAGDTKPVLRALKRMLAMRHYKRAETVDGKVDTRALEEVGLTEAQAQEMYRYLAIA
                     NYEDRFVVPSSHRELAREAFPEKNGCGFTFGDGCHGSDTKFNLFNSRRIDAIDVTSKT
                     EPHP"
     gene            complement(29769..33512)
                     /locus_tag="RHX21_002235"
     CDS             complement(29769..33512)
                     /locus_tag="RHX21_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit alpha"
                     /protein_id="HDV1987407.1"
                     /translation="MSKFLDRFRYFKQKGETFADGHGQLLNTNRDWEDGYRQRWQHDK
                     IVRSTHGVNCTGSCSWKIYVKNGLVTWETQQTDYPRTRPDLPNHEPRGCPRGASYSWY
                     LYSANRLKYPMMRKRLMKMWREAKALHSDPVEAWASIIEDADKAKSFKQARGRGGFVR
                     SSWQEVNELIAASNVYTIKNYGPDRVAGFSPIPAMSMVSYASGARYLSLIGGTCLSFY
                     DWYCDLPPASPQTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGT
                     KTVAVTPDYAEIAKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDNPSQYFTDYVRRY
                     TDMPMLVMLEERDGYYAAGRMLRAADLVDALGQENNPEWKTVAFNTNGEMVAPNGSIG
                     FRWGEKGKWNLEQRDGKTGEETELQLSLLGSQDEIAEVGFPYFGGDGTEHFNKVELEN
                     VLLHKLPVKRLQLADGSTALVTTVYDLTLANYGLERGLNDVNCATSYDDVKAYTPAWA
                     EQITGVSRSQIIRIAREFADNADKTHGRSMIIVGAGLNHWYHLDMNYRGLINMLIFCG
                     CVGQSGGGWAHYVGQEKLRPQTGWQPLAFALDWQRPARHMNSTSYFYNHSSQWRYETV
                     TAEELLSPMADKSRYTGHLIDFNVRAERMGWLPSAPQLGTNPLTIAGEAEKAGMNPVD
                     YTVKSLKEGSIRFAAEQPENGKNHPRNLFIWRSNLLGSSGKGHEFMLKYLLGTEHGIQ
                     GKDLGQQGGVKPEEVDWQDNGLEGKLDLVVTLDFRLSSTCLYSDIILPTATWYEKDDM
                     NTSDMHPFIHPLSAAVDPAWEAKSDWEIYKAIAKKFSEVCVGHLGKETDIVTLPIQHD
                     SAAELAQPLDVKDWKKGECDLIPGKTAPHIMVVERDYPATYERFTSIGPLMEKIGNGG
                     KGIAWNTQSEMDLLRKLNYTKAEGPAKGQPMLNTAIDAAEMILTLAPETNGQVAVKAW
                     AALSEFTGRDHTHLALNKEDEKIRFRDIQAQPRKIISSPTWSGLEDEHVSYNAGYTNV
                     HELIPWRTLTGRQQLYQDHQWMRDFGESLLVYRPPIDTRSVKEVIGQKSNGNPEKALN
                     FLTPHQKWGIHSTYSDNLLMLTLGRGGPVVWLSEADAKDLGIADNDWIEVFNSNGALT
                     ARAVVSQRVPAGMTMMYHAQERIVNLPGSEITQQRGGIHNSVTRITPKPTHMIGGYAH
                     LAYGFNYYGTVGSNRDEFVVVRKMKNIDWLDGEGNDQVQESVK"
BASE COUNT         8627 a         8483 c         7944 g         8647 t
ORIGIN      
        1 caataatttt ctctaagtca cttattcctc aggtaattgt taatatatcc agaatgttcc
       61 tcaaaatata ttttccctct atcttctcgt tgcgcttaat ttgactaatt ctcattagcg
      121 actaatttta atgagtgtcg acacacaaca ctcatattaa tgaaacaatg caacgcaacg
      181 ggagaaataa catggccgaa catcgtggtg gttcaggaaa tttcgccgaa gaccgtgaga
      241 aggcatccga cgcaggccgt aaaggcggtc agcatagcgg cggtaatttt aaaaatgatc
      301 cgcaacgcgc atctgaagcg ggtaaaaaag gcggtcaaca aagcggtggt aataaatcag
      361 gtaaatcctg attcaccgtt aattattaat atcagctgat aaagataatt gcatctgcgg
      421 gccgtatggc tcgcagtgat ttcactggag aaaaatatga atatgaagac cattgaagat
      481 gtatttattc acctgctttc agatacctac agcgcagaaa aacaattaac ccgggcactg
      541 gcaaaactcg caagagcaac atcaaatgaa aaattaagtc aggcttttca tgcgcacctc
      601 gaggaaactc atggacagat tgaacgtatt gatcaagttg tggagtccga atcgaacctg
      661 aaaattaagc gcatgaaatg tgtggcaatg gaaggtctta ttgaagaagc taatgaggtc
      721 atcgaaagta ccgagaaaaa cgaagtgcgt gatgccgcac tgattgccgc agcacagaaa
      781 gtcgagcatt atgagattgc cagttacggg acattagcga cgctggctga acaattaggt
      841 taccgtaaag cagcgaagct tctgaaagaa accctggaag aagaaaaggc caccgacatc
      901 aaactgactg atctggccct taataacgta aataagaaag ccgaaaataa agcctgaaat
      961 atgaatttta acttttagtc attttataaa gaggacattt tcatgaatcg tattgaacat
     1021 tatcatgact ggttacgtga cgcccacgca atggaaaagc aagccgaatc tatgcttgaa
     1081 tccatggcca gtcgtataga taattatcct gaactacgcg ctcgtattga acaacatctt
     1141 agtgaaacca aaaaccagat tgttcaactg gaaactattc ttgatcgtaa tgacatttca
     1201 cgttcagtca ttaaagattc catgagtaaa atggctgcgc ttgggcagtc aatcggtggt
     1261 atattccctt ctgatgaaat agttaaaggc tctattagcg gatatgtctt cgagcaattt
     1321 gaaatcgcct gttacacctc actattagca gcagcaaaaa atgccggtga tacagtctca
     1381 attccgatca tcgaagcgat tttaaatgag gaaaagcaaa tggccgactg gctgattcag
     1441 catattccgc aaacaactga gaaattttta attcgttctg aaactgatgg cgtagaagcg
     1501 aagaaataat accctttata ccatgtcctt attgaccccg tatattacgg ggtcgttttt
     1561 gtgcggaatt aaaaacgata tcctgctgag aacataaaca cccacggatc gaggcgtacg
     1621 ctatcgtgtt gctgtgcacc gcctagctta taattggcgg tggtatcgat atccatgtac
     1681 cacactgaca tgttaaccaa ccagtcacgg ttaatcagat aatcaacccc cacctgcccg
     1741 gcagctcccc aggaatcttt cagactgaga tcggaaagcc ccgcctcttt gccatgatcg
     1801 ttaaatccat tatcaaagaa ggtggtgtag ttaataccgg ccccaacgta aggacggaat
     1861 ttgctgctgg catcaccaaa ataccactgc gccatcagtg ttggcggcag atggtgaacg
     1921 gttgcaatat cgccggtcgc ccgggtgccg attttatggc ggaacggcgt cgctgccagt
     1981 aattccacac caatgttgtc ggtcgccata taagtaaacg tcaagcccag ttgagtgtta
     2041 ttggtcacgc tgaatccacc cagacttcct aacgtaccac cagcaccttc tgttggacgt
     2101 acggttgcag aacctgcacg cataaaaaat tcgcctgctt catgcgcaaa ggcactgcca
     2161 gaaagaagag ttgttactgc caaagccgcc actgttaact ttttcatatc cgctccgtcg
     2221 ttatggttat aaaaacgtga cgaatatacc tacattggag taacaaatga tcctacatag
     2281 atcacattac atatgataat tcaccattta ttgatctgga ttaatttaga agttgcattg
     2341 agaatcctgg ttaatgtgat ttaaatcaat ttttaaatat tttctctacg caaatattaa
     2401 ctcgatcgcc acttgccgcg gtttgcccac gcctgaaggc cagcaattac ctccgcttta
     2461 caaagatatg cttttccata caagacctga tgctgccacc cgaggcttaa ccagggtaca
     2521 attgcccgct aattaacacc tgcataaaac tcaaggagag tgcatgtcta tcacggcgca
     2581 gtccgtatac cgtgacaccg gaaatttctt ccgtaatcaa tttatgacca ttctgttggt
     2641 atcgttgcta tgtgcgttta tcacagtggt gttagggcat gttttctcac ccagtgatgc
     2701 acagcttgcg cagctcaatg acggcgtgcc cgttagcggc agtagtgggt tgttcgacct
     2761 ggttcagaat atgtcaccgg aacagcaaca aattttgctg caggcttcag cggcgtccac
     2821 tttttcagga ttaatcggta acgccattct cgccggaggc gtaatattaa ttatccagct
     2881 ggtgtctgcg ggtcagagag tcagtgcgct gcgagctatt ggtgccagtg cgccgatatt
     2941 gcccaagtta tttattctga tttttctgac taccctttta gtacagattg gcatcatgct
     3001 ggtggtcgtt ccgggaatta tcatggccat tttactggcc ctggcaccgg tgatgctggt
     3061 acaggacaaa atgggcattt ttgcctcgat gcgtagcagt atgcggctga cttgggcgaa
     3121 tatgcgtctg gtggcacccg cagtactgag ctggttgctg gcaaaaacac tgttgctgct
     3181 ttttgcctct tcttttgccg cattaacccc ggaaattggt gccgtactgg cgaacacctt
     3241 gagcaacctg atttctgcca tattgctcat ctatctgttc cgcctgtata tgttgattcg
     3301 ccaataacct taagcatttg attacggaat cgtaaaatga agcagtttct tgatttttta
     3361 ccgctggttg tctttttcgc gttttacaag atttatgaca tctacgcggc tactgcggcg
     3421 ctgatcgtcg ccacggcgat tgtgcttatc tatagctggg ttcgctttcg taaggttgag
     3481 aagatggccc tgatcacttt tgttctggtg gtcgtcttcg gtggcttgac gctgttcttc
     3541 cacaatgatg agtttattaa atggaaggtt acagtcattt atgctctgtt tgcgggagcc
     3601 ctgttagtca gccaatgggt gatgaaaaag ccgctaattc agcggatgct gggtaaagaa
     3661 ctcacgctgc cgcaaccggt atggtcgaag ctaaatctgg cttgggctgt tttctttatc
     3721 ctttgcggtc tggcaaacat ctacatcgca ttctggctgc cgcaaaatat ttgggtcaac
     3781 tttaaagtct ttggcctgac cgcccttacc ttaatcttca cattgttaag cggtatctat
     3841 atctaccgcc acatgccgca ggaagataaa tcctaaccag actgccagtc cttcggggct
     3901 ggcgctgtat ctcctctgtt ctcctcagga aaatcatagt agcatcgcgc ctgtgatttt
     3961 ccttttaagt cggttttacc atgtctacaa cacataacgt ccctcagggc gatcttgttt
     4021 tacgtacttt agccatgccc gccgatacca atgccaatgg tgacatcttt ggtggttggt
     4081 taatgtcaca aatggatatt ggcggcgcta ttctggcgaa agaaattgcc cacggtcgcg
     4141 tagtgactgt gcgggttgaa ggaatgactt tcttacggcc ggttgcggtc ggcgatgtgg
     4201 tgtgctgcta tgcacgctgt gtccagaaag ggacgacatc ggtcagcatt aatattgaag
     4261 tgtgggtgaa aaaagtagcg tctgaaccaa tcgggcaacg ctataaagcg acagaagcat
     4321 tatttaagta tgtcgcggtt gatcctgaag gaaaacctcg cgccttacct gttgagtaat
     4381 agtcaaaagc ctccggtcgg aggcttttga ctttctgctt actgaatttc ggtggtgccg
     4441 ttaattttaa acaggatatt caccacaatc ccactgcctg gcttacccgg ctcataacgc
     4501 catctgcgca tcgcattttt cacctcacgc tcaaacatgt tcgcaggctt ggctgagagg
     4561 atttgtacgt tatccacgcg accatccggc gtgacgtcaa atttaacttt aacctgccct
     4621 tcaatgcgca atgcctgtgc tcgtgccgga tactgcggct gattacggct taatgcgcgt
     4681 ggtcctgaag ccacactggt aaccggcttg ctggttgcag ccgttgccgt acttgatgtc
     4741 aggcgcgcgg gtgccgtatt ttcaaacggt gatgccggac gcgactctac gggtttgata
     4801 tcgcgttttg gctgctcctg tacctttttc accggcttcg gttttggctt aggtttcggc
     4861 ttcggctttt caatgaccac cggtgcttct tttggcggtt cggggatcgg ctcaggttcc
     4921 ggttctggct ctaccaccgg ctccggtggc ggctgaacgg cttgtggcgg ttcgagatca
     4981 gcaggcgcaa ccatcgtgac agaaattggc tgcgcaggcg caggtagttc aataacctga
     5041 tgtaccgagg tatagagcag acccgccaca acagcaccat gaatgcagac cgaaagtaac
     5101 gtcggccagg ggaagcggcg aggtaaatca agggtcattg aagtcataat catttcagta
     5161 gaaaaaccag gtctcgattt taaatgcaaa tagcaatcat attcaataag gcaagacgat
     5221 caggatcagt gaaaatgtca tttttggcgt aattgacctt actttatgca tggtcttaac
     5281 aaagacatca tctttccgtt gcagatcttc gccctttcaa ataacgtact ttacaacttt
     5341 cccgaacaag gagttgtgcc cgtgttgtat gttatttacg ctcaagacaa agctgatagc
     5401 ctcgaaaaac gcctttccgt tcgtccggca catttagcac gtttacagtt actgcatgat
     5461 gaaggtcgtt tgttgacagc tggtccaatg ccagcggtag acagtaacga tccaggggct
     5521 gcgggattta ctggctcaac cgttattgct gaatttgaat cgctggaagc agctcaggcc
     5581 tgggccgatg ctgacccgta cgtagcggca ggtgtctatg aacacgtttc agtgaaacca
     5641 tttaagaaag tgttctgaat agagattcaa tatttaaggg cacggttttt gcaaccgtgt
     5701 tcttgtttgg cctttcctta tagccggtca gtgcattcac taccacaagc agataataac
     5761 tttatctgta tttctttata tgatgtgaac atattcagga aaatgccctt tcctgacgca
     5821 gagttgctcg ctcaaaacct ttgattactg ccgataaagt catctactat tgtttaacac
     5881 attcacgcgc tgcatgtatg ttcagaaaat gtgcacgcta agataattaa acaaaattgt
     5941 ggttacagag gtatcagtga gtcactgggc tacattcaaa caaacagcaa caaatttatg
     6001 ggtgacccta cggcacgaca ttctcgcgct ggccgtcttt ttaaatggat tgcttatttt
     6061 taaaacaatc tatggtatgt cggtcaattt gcttgatatt ttccatatca aagcattttc
     6121 agagttggat ctctccttgc tggcaaacgc cccactattt atgctcggcg tctttcttgt
     6181 cctgaactcc attggcttac tgttccgggc aaagctcgca tgggcaatca gtatcatttt
     6241 gttgttgata gcgctaattt acaccctgca tttttatccc tggctgaaat ttagtattgg
     6301 attttgcatt tttacgctgg tgtttttgct gatactgcgc aaagacttct cccacagtag
     6361 cgccgcagcc gggacaattt ttgcatttat tagtttcacg acattactgt tttactcaac
     6421 ctacggtgcg ctttatttaa gcgaaggttt taatccgcga atagaaagtt tgatgaccgc
     6481 gttctatttt tcgatagaaa ccatgtcaac cgtcggctat ggcgatattg tccctgtttc
     6541 tgaatcagca cgattgttca ctatttcggt cattatttcc ggcattaccg tttttgccac
     6601 atctatgacc tcaatttttg gtccgcttat ccgcggggga ttcaacaaac ttgtaaaagg
     6661 aaacaatcat acaatgcatc gtaaagatca ttttattgtt tgcggacatt cgattctcgc
     6721 catcaatacg atcctgcaac tgaatcaacg cggacaaaac gtaacggtta tcagcaactt
     6781 gcctgaagat gatatcaagc aacttgagca acgcttaggc gataacgctg atgttatccc
     6841 cggtgacagt aatgacagtt cagtattaaa gaaagcggga atcgatcgtt gccgggccat
     6901 tctggcgctg agtgataacg atgcagataa cgcgtttgtt gtactctcgg caaaagatat
     6961 gagcagtgat gtcaaaacag ttctcgccgt cagtgatagc aaaaacctga ataagattaa
     7021 gatggtacat ccggatatca ttctctcacc gcaactgttt ggcagcgaaa ttctggcgcg
     7081 agttttaaat ggtgaagaga ttaataatga tatgctcgtt tcaatgttgt tgaactccgg
     7141 tcatggcatt ttcagcgata acgatgaaca agaaacgaaa gctgacagta aagaatcagt
     7201 gcaaaaatag agtttaaaga cgaaagagta aacttattgg gcaccgcaat ggtgcccagt
     7261 atatttagat attgtagatc gcaaacaata acgagttacg ctgtttgttt agaatgcact
     7321 tcctgatgct gtggatacgc atatttcggc gcgattgccc ctcaagccaa cgcgatttac
     7381 gtcggctagc ctgacgctgc atgcgccagc gccccacttc cgttctactc cgcttcatgt
     7441 taactactct atgcaataac agaatggtca ttataccccc acccccgacg ctgaccagtg
     7501 cttttcccgc gtttttattt gccagatgaa tccatatgcg taaactcata acaatgcgct
     7561 ttcaaaagga tttctaatct atgacaaccg tttatacgtt ggtgagttgg ttggccattc
     7621 tgggatactg gttgctcatt gcaggcgtaa ctttacgcat tctaatgaaa cgacgcgcag
     7681 ttccctccgc gatggcctgg ctgttgatta tttacattct gccgttagtc ggaattattg
     7741 cctatcttgc cgttggcgag ctccatttag gcaaacgccg cgctgagcgc gccagagcga
     7801 tgtggccttc caccgcaaaa tggcttaacg accttaaagc ctgtaagcat atcttcgccg
     7861 aagaaaatag cagtgtcgct gcgccattat tcaagctttg cgagcgtcgt caggggatcg
     7921 ctggggtcaa agggaatcag ctacaactga tgaccgagtc agatgatgtg atgcaggcgt
     7981 taatccgcga catccagctc gcgcgccata atattgagat ggtgttttat atctggcagc
     8041 ccggcggcat ggcggaccag gtggctgaat cattaatggc ggctgcacgg cgtggtattc
     8101 attgccgatt gatgctcgac tccgccggga gtgtggcttt tttccgcagc ccgtggcccg
     8161 agctaatgcg taatgccggt attgaagtgg tcgaagcctt aaaggtcaat ctgatgcgtg
     8221 tgtttttacg ccgtatggac ctgcgccaac atcgcaagat gatcatgatc gataattaca
     8281 tcgcgtacac cggcagcatg aatatggtcg atcctcgcta cttcaaacaa gatgcgggcg
     8341 tagggcaatg gattgatctg atggcgcgta tggaaggccc catcgccacc gcgatgggga
     8401 ttatttattc ctgcgactgg gagattgaaa ccggaaaacg tattctgccg ccaccaccag
     8461 atgtcaatat tatgccgttt gaacaggcca gcggtcacac cattcacaca attgcttctg
     8521 gccccggctt tccggaagat ctcattcacc aggcattatt gactgcggct tattcggcgc
     8581 gtgaatattt gatcatgacc acgccctact ttgtgccaag cgatgattta cttcatgcga
     8641 tttgcacggc ggcgcagcgc ggggtggatg tcagtattat ccttccgcga aaaaatgact
     8701 cgatgctggt cggctgggcc agtcgcgcat tctttacgga acttcttgct gctggggtta
     8761 aaatttatca gtttgaaggc gggttactgc ataccaagag cgtgctggtc gatggcgaac
     8821 taagtctggt tggcaccgtt aaccttgata tgcgtagtct gtggctgaat ttcgagatta
     8881 ccctggcaat cgacgataaa ggttttggtg cagaccttgc cgccgttcag gacgattata
     8941 tttcgcgttc acgtctgctc gatgcccgtt tatggctaaa acgtccatta tggcaacgtg
     9001 tcgccgagcg actgttttac ttcttcagtc cgttgctgta aaacgtcgcc aacagaggtt
     9061 aaacaggtag tgactatgga tatggatcta aacaatcgcc tgactgaaga tgaaacgctt
     9121 gagcaggcct acgatatttt tctcgaactg gctgccgaca atctcgatcc agctgatgtt
     9181 ctgctgttca atcttcagtt tgaagagcgc ggcggcgcgg agttattcga tccggcggaa
     9241 gactggcagg aacatgttga tttcgatttg aacccagact tttttgccga agtggtgatt
     9301 ggtctggcgg acagtgaaga tggtgaaatc aacgatgttt tcgcccgcat tctgttatgc
     9361 cgcgaaaaag atcacaaact ttgccatatc atctggcggg aataaataat cgcttttagc
     9421 gtgaaaaagg gctgacaact gtcagccctt attgtgttta aagcggatcg actttcaggc
     9481 aagaaacggc gtgtctgaaa ctcccctcca gaacaggacg tgttttggcg cactccggac
     9541 cggcaatcgg gcaacgggta cggaaaacac aaccggaagg cgggttgatc ggcgacggta
     9601 attccccttc cagtaactgg atggttttgt tcttctccag atccggatca ggtatgggga
     9661 ctgccgacat caatgccctg gtgtaaggat gtagtggatt gtggtagacc tcatcatagg
     9721 tccccagttc taccgcatgg ccgagataca tcaccaacac acgatcggaa atgtgtttta
     9781 ccacggccag gtcatgagcg ataaaaatta atgacaatcc catctcacgt tgcagctgct
     9841 ggagcaggtt gaccacctgc gcctgaattg acacgtccag cgccgaaacc ggctcatcgc
     9901 agataatcag cttcggttca agaataagag cacgagcaat cccgatacgc tggcactgcc
     9961 caccggagaa ctcatgcgga tagcggttaa tcaggttagg caataacccg actttcagca
    10021 tcatcgcctt cacgcgctcg cgaacttcct ggcgtgacat tttcggatga taagtacgca
    10081 gtggttcagc gatgatctcg ccgatggtca tacgcgggtt tagcgatgcc aacggatcct
    10141 ggaaaatcat ctgaatatca ctgcgaacgg cacgccattc atcgggcttc atgcccagca
    10201 actctttacc taaccaggca acatgaccgt cggtcgcctt gaccaaaccg atgatggcgc
    10261 gagcaaaggt ggacttaccg catcccgatt cccctaccac acctaatgtt tccccttcat
    10321 acaggcgaag agtgacacca tcgacggctt tgagcgtttt cggcggttgc cagaaccact
    10381 gtttgccatc tttgatttca aagtgcactt taagatcggc gatttcaagg aggacttttc
    10441 ttccttcagt tacagcattc ataacagttc ctccaccggt ttaaagcaag cacgcagacg
    10501 gccaggcgta aactcttcca gcggcggtgc gctactacaa atttccatcg catgtggaca
    10561 acgtggctgg aacgggcaac ctttcggtaa tcgcagcaag tttggcggat tacccgggat
    10621 ggtcaacatt gtttcacctt ccgcatcaag acgcggcacc gcgttgagca aaccgataga
    10681 ataaggatga acgggttgat aaaagacatc gcgcgcattg ccatattcca tcgtgcgccc
    10741 ggcgtacatt accagcactt tgtcgcagat ccccgccacc acgccaagat cgtgggtgat
    10801 cataatgatg gcggtattaa attcccgctt cagttcattt aatagcgtca tgatctgcgc
    10861 ctgtacggtg acgtccagcg cagtagtggg ttcatccgca atcagtagct taggtcgaca
    10921 tagcaatgcc atcgcaatca tgactcgctg acgcatgccg ccagaaaatt cgtgcgggta
    10981 cattttcatg cgtttacgcg cttccggcat ttttaccgca tcgagcatcc gcaccgactc
    11041 ttcaaacgcc tcagctttgc tcatgttctt atgcagcatc agcacttcca ttaactgctc
    11101 accgacgcgc atatagggat tcaacgaagt cattgggtcc tgaaaaatca ttgagatttg
    11161 ttcagcgcgc agtttattga gttcatgctc tggcaaattg aggatttcac gcccattgaa
    11221 ggttgccgat ccgccaatac gtccgttggc agccaacagg cccatcaacg caaatgcagt
    11281 ttgcgattta cccgaaccag actcacctac aatacccagc gtttctccgg cacgtaggga
    11341 aaaattcaaa tcattgaccg ccgtgacgtc gccgtccggg gtactaaagg tgacacgcaa
    11401 atctttcacg ttcagcagtg cgtcagcctg ttgttgtgcg agcggcacag ttgcagtttc
    11461 aattacgctc atggctgcac tccttaacga tctttcgggt cgagggcatc acgcaagcca
    11521 tcgccgataa agttgaaaca aaacagcgtc accacgagga atcccgctgg gaacaacaat
    11581 aaccatggag agacttccat cgagttcgcg ccatcactca gcaatgcacc ccagctgctt
    11641 aacggctctt gcgtacccaa ccccaggaag ctaaggaaag attcaaagag gatcatgctg
    11701 ggcaccagaa gtgatgcgta gaccaccacc acaccgagta cattcggcac aatgtggcga
    11761 ataacaatgc ccgatgtcga tacaccgcca acttgtgccg cctcaataaa ctctttgcgc
    11821 ttcagactca gggtttgccc acgcacaata cgagccatat ccagccagga aaccatgcct
    11881 atcgccacga aaatcagcag gatgttttga ccgaaaaagg tcaccagcaa aatgacgaag
    11941 aacatgaatg ggaaggagtt gaggatttcc agcagacgca tcattaccga atccacttta
    12001 ccgcccagat aaccggaaag cgaaccataa agtgtcccga cgaccactgc caccagtgcc
    12061 gcagcaacac cgaccatgag tgagatacgc ccgccaatcg caacgcgcac aagcaggtcg
    12121 cgaccggatg agtcagtacc aaagtagtga ccggactcca tatccggggc gctggacatc
    12181 atcgcccagt cagtatcgtc ataggcaaac tgcgaaagca tcggtgccag gattacaaat
    12241 aacgcgatca gcaccagcac tatcagactg gcaaccgccg cacggttatg cataaaacgt
    12301 cgacgtgcgt cctgccacaa gctgcgccct tcgacctcca gcttttcact gaaattttcc
    12361 agcgtctcgc tgtttttctt acttaacatc atcgcgagct ccagtatcag taacggattt
    12421 tcgggtcgat aaccgcatat agcacatcga caatggcatt aaacaaaatg gttaaagcac
    12481 caaccaggat ggtcaggctt aacactaagg aatagtcacg gttcaatgcg ccattaacga
    12541 acagttgccc aatccccggc aaaccataaa tggtttcgat aaccatagaa ccggtaataa
    12601 tgccgacaaa tgcggggccc atataggaga gcacgggtaa cagagcaggt tttaatgcgt
    12661 ggcgtaaaat gatccgccgc ataggtaacc ctttcgcccg ggcagtacga ataaaattgg
    12721 agtgtaatac ttcaatcata gagccacggg taatacgcgc aatactggcg atataggcga
    12781 gtgacaacgc caccatcggc aatatcatga atttaagcgc cccaccattc cagccaccgc
    12841 ccggcagcca atgcaaaatg atcgcaaata tcatgactaa taatggcgca accacaaaac
    12901 tggggataac aaccccggtc attgccagcc ccatcacggt atagtcccat ttggtgtttt
    12961 gttttaatgc ggcaataacg ccagcactaa cacccagtat taccgcaagg aaaaatgctg
    13021 cggctcccag tttggcagaa acgggaaaac tggatgccac caggtcattg accgaataat
    13081 ctttatattt aaacgatgga ccgaaatcac cgtgcgccag ttgtttcagg tagctgaaat
    13141 actgtgtcat gatcggatca ttaagatgat atttcgcttc gatattggcc atcacttcag
    13201 gcggtaaagt acgttcgccg gtaaaagggc ttcccggcgc gaggcgcatc ataaagaacg
    13261 aaatagtaat aagaataaat agcgtcggaa tcgcttccag acagcgacgt agaataaatt
    13321 ttaacattgc cctaccttct ggcctgtgcc ttctgtaatg cgataaaaat cagacaccgt
    13381 ggagcaggac actcctgccc cacgtattgc cattagtgct tcacaatgta catattccgg
    13441 gtataggtat tatccaacgg atctttgccg gtatagccac caacccacgg tttcaccaga
    13501 cgcgcattca cgtagtaata aacaggaaca atggccgaat ccttatccag ctgttgttct
    13561 gctttagtgt acagagctgt gcgctgcgcc tcgtcagtca ctttcagcgt ttccgccata
    13621 atgctgtcaa aggccgggct cttataatgc gcggtattca tcgagctgtt cgaaagcatg
    13681 gtgttcagga aggaagttgg ttcgttgtag tcagcacacc agcctgcacg ggccacatca
    13741 aaagtaccct ggtgacgggt gtcgaggaac gttttccact cctggttaac cagtttgacg
    13801 tttacaccaa tgtttttctt ccacaatgaa gaggcagcaa tcgccagctt tttatgcaga
    13861 tcggaggtgt tatacaacag gttgatggtc aacggtttgt ctgcggtata acccgcttca
    13921 gccagcagtt ttttcgcttc ttcgttacgt ttttcctggc tccagccaaa ccattccggc
    13981 tgagtcaatt ttgcgccatc agtatacggt ggagtgtaac cataggcggg catgtcgccc
    14041 tgcgctttca ctttattaac aatgatatcg cggtccatac ctagtttcag tgcggtacgc
    14101 acacgcacat cgttgaatgg cggtttctgg ttgttaatct cgtaatagta agtgcacagg
    14161 tatggatcaa cgtgaacttc gtccgggatc tcttttttca gcttctggaa caattcgatc
    14221 ggcatgttgt tataagtcat gtcgatttca ccactacggt agcggttgac atcggtaact
    14281 tcagaagcaa taggcaaata ggttacctgg ttaataacgg ttttcgcgtt gttccagtag
    14341 gtcgggctgc gttcaagaac gattcgttcg tttacgaccc aatcttttaa ggtataggca
    14401 ccgttggtga cgatattacc aggctgggtc catttttcgc cgaatttctc gatagcggct
    14461 tttggcaccg gtgaagttga tgggtgaaca agtaatttat agaagtacgg aacgggttca
    14521 cttaaggtga cttctaatgt gtgatcatca atagctttca cgccgagatc ggtaatcggt
    14581 tttttccctt caagaatttc atcaataccg gcgatatgcc catattgcag ataactggca
    14641 tacggagaag cagtgttcgg atcaacagaa cgttgccagc tatacacaaa gtcttgtgct
    14701 gtgactggcg tgccatcaga ccatttcgca tctttacgca aatggaaggt ccagactttc
    14761 gcgtctttat tatcccagga ttcagcgacg ccaggtgctg gatgaccgtc aagatcgctg
    14821 accagtaagc cttcaaacag gtctcggctg atattagact ccggaacacc ttcaattttg
    14881 tgcggatcta atgactgaac ttctgaacca ttgttacgta ccagtgtttg tttttccgcc
    14941 agtgtgacgc ctgcgggtac atcagctgcc agcgcgacat tccctgccat tagcgcagcc
    15001 agaacgccag ctgctactaa acttctcttg gtgatgttgg tcattgtttt ttggactccc
    15061 tcattataat tactggtatt aaccagcatg tgtaatcccg gattgggacc ctgcacaggc
    15121 tcggagactt tctgctgtca ggttacttta tcgttacgta ttactatcac cgactttatt
    15181 tattctggtg attcagacga tcaccttatg tcgattcgta ctgtgtctcc cctgtcgaga
    15241 cacattattc tttcgcgacg ctctttaatt gttaattatt ctcattacca ataaagaatc
    15301 gtctggcggt tgcccggaaa gtaccaaatg cggttcttac tcgccaatac attttgcaaa
    15361 attgttaagc aattctcttt tattgaccgt atcagaatct atagcttgca tccatgcctt
    15421 aacaaacatc tttcaattca atcaaataga gattggctaa gcatgtctat cttttctgat
    15481 tacagttcca gtagtgaaat gcacaataat ttaacaattg attattattt agcactttcc
    15541 tctaccaaag gcagtggaat tactaatatc atttcaatta ttcttcagca agcccaggat
    15601 tatgatgtgg cgaaaataac atgatggtga ggagaagcag ttaaggaaat ccttataact
    15661 aactgtaatt tgagaagaat attttaccta ttccttttgc ttttgataac tgcgcgggaa
    15721 caaagtaaaa ataatgacga agtaaacgga gcatggcagc tccgtttcat ttgaaaggaa
    15781 ttaattaagc aggccgggga aaatcccctt aataccagta acgataaatt caatccccaa
    15841 tgccatcagc aatagcccca taatacgcgt aatcacgttg atgccggtct ggcgtaaaac
    15901 ccgtaccagc cacggtgcca tgcggaacaa tccccagcaa cataaagcga acaatgcaat
    15961 agccacaaag aaaccaaaca gatagctaat gctgtgataa cgcgtacccc agacgatggt
    16021 agaactgatc gcccctggcc ccgccatcaa cggcaacgcc aatggcacca caccaatgct
    16081 ttcacgtacc gcggtttctg atttttcttg cttgttctgt ttatcctcgc caagcttgcc
    16141 gctgatcatc gacatcgcta tcgtcaccac caggatgccc ccggcgatac ggaacgaatc
    16201 aattgatata ccaaaaagtt gcagaatcgt gtcgccgaga aaaagcgaga tccacaagat
    16261 aatggccaca gacaggttgg ctgtaaggtt agttttgttt cgcgctgccg ctgtctgata
    16321 actggtcatg ctgataaaga cgggaataat ccctaccggg ttgaccagcg caaataaccc
    16381 gatgaaaaat ttgaagtaaa cgggaaaatc aaaaaaggtc tgaatcacgg ttagctccga
    16441 agcaaaagcc ggataatgtt agccataaat aaggttgaaa agacgcgctg acaatacgcc
    16501 ttttgacagc atttttcacc tcctaactac ttaaaattgc tatcattcgt tattgttatc
    16561 tagttgtgca aaacatgcta atgtagccac caaatcatac tacaatttat taactgttag
    16621 ctataatggc gaaaagcgat gctgaaaggt gtcagctttg caaaaatttg atttggatca
    16681 cgtaatcagt acccagaagt gagtaatctt gcttacgcca cctggaagtg acgcattaga
    16741 gataataact ctaatgttta aactctttta gtaaatcaca gtgagtgtga gcgcgagtaa
    16801 gcttttgatt ttcataggtt aagcaaatca tcaccgcact gactatactc tcgtattcga
    16861 gcagatgatt tactaaaaaa gtttaacatt atcaggagag cattatggct gttactaatg
    16921 tcgctgaact taacgcactc gtagagcgtg taaaaaaagc ccagcgtgaa tatgccagtt
    16981 tcactcaaga gcaagtagac aaaatcttcc gcgccgccgc tctggctgct gcagatgctc
    17041 gaatcccact cgcgaaaatg gccgttgccg aatccggcat gggtatcgtc gaagataaag
    17101 tgatcaaaaa ccactttgct tctgaatata tctacaacgc ctataaagat gaaaaaacct
    17161 gtggtgttct gtctgaagac gacacttttg gtaccatcac tatcgctgaa ccaatcggta
    17221 ttatttgcgg tatcgttccg accactaacc cgacttcaac tgctatcttc aaatcgctga
    17281 tcagtctgaa gacccgtaac gccattatct tctccccgca cccgcgtgca aaagatgcca
    17341 ccaacaaagc ggctgatatc gttctgcagg ctgctatcgc tgccggtgct ccgaaagatc
    17401 tgatcggctg gatcgatcaa ccttctgttg aactgtctaa cgcactgatg caccacccag
    17461 acatcaacct gatcctcgcg actggtggtc cgggcatggt taaagccgca tacagctccg
    17521 gtaaaccagc tatcggtgta ggcgcgggca acactccagt tgttatcgat gaaactgctg
    17581 atatcaaacg tgcagttgca tctgtactga tgtccaaaac cttcgacaac ggcgtaatct
    17641 gtgcttctga acagtctgtt gttgttgttg actctgttta tgacgctgta cgtgaacgtt
    17701 ttgcaaccca cggcggctat ctgttgcagg gtaaagagct gaaagctgtt caggatgtta
    17761 tcctgaaaaa cggtgcgctg aacgcggcta tcgttggtca gccagcctat aaaattgctg
    17821 aactggcagg cttctctgta ccagaaaaca ccaagattct gatcggtgaa gtgaccgttg
    17881 ttgatgaaag cgaaccgttc gcacatgaaa aactgtcccc gactctggca atgtaccgcg
    17941 ctaaagattt cgaagacgcg gtagaaaaag cagagaaact ggttgctatg ggcggtatcg
    18001 gtcatacctc ttgcctgtac actgaccagg ataaccaacc ggctcgcgtt tcttacttcg
    18061 gtcagaaaat gaaaacggct cgtatcctga ttaacacccc agcgtctcag ggtggtatcg
    18121 gtgacctgta taacttcaaa ctcgcacctt ccctgactct gggttgtggt tcttggggtg
    18181 gtaactccat ctctgaaaac gttggtccga aacacctgat caacaagaaa accgttgcta
    18241 agcgagctga aaacatgttg tggcacaaac ttccgaaatc tatctacttc cgccgtggct
    18301 ccctgccaat cgcgctggat gaagtgatta ctgatggcca caaacgtgcg ctcatcgtga
    18361 ctgaccgctt cctgttcaac aatggttatg ctgatcagat cacttccgta ctgaaagcag
    18421 caggcgttga aactgaagtc ttcttcgaag tagaagcgga cccgaccctg agcatcgttc
    18481 gtaaaggtgc agaactggca aactccttca aaccagacgt gattatcgcg ctgggtggtg
    18541 gttccccgat ggacgccgcg aagatcatgt gggttatgta cgaacatccg gaaactcact
    18601 tcgaagagct ggcgctgcgc tttatggata tccgtaaacg tatctacaag ttcccgaaaa
    18661 tgggcgtgaa agcgaaaatg atcgctgtca ccaccacttc tggtacaggt tctgaagtca
    18721 ctccgtttgc ggttgtaact gacgacgcta ctggtcagaa atatccgctg gcagactatg
    18781 cgctgactcc ggatatggcg attgtcgacg ccaacctggt tatggacatg ccgaagtccc
    18841 tgtgtgcttt cggtggtctg gacgcagtaa ctcacgccat ggaagcttat gtttctgtac
    18901 tggcatctga gttctctgat ggtcaggctc tgcaggcact gaaactgctg aaagaatatc
    18961 tgccagcgtc ctaccacgaa gggtctaaaa atccggtagc gcgtgaacgt gttcacagtg
    19021 cagcgactat cgcgggtatc gcgtttgcga acgccttcct gggtgtatgt cactcaatgg
    19081 cgcacaaact gggttcccag ttccatattc cgcacggtct ggcaaacgcc ctgctgattt
    19141 gtaacgttat tcgctacaat gcgaacgaca acccgaccaa gcagactgca ttcagccagt
    19201 atgaccgtcc gcaggctcgc cgtcgttatg ctgaaattgc cgaccacctg ggtctgagcg
    19261 caccgggcga ccgtactgct gctaagatcg agaaactgct ggcatggctg gaaacgctga
    19321 aagctgaact gggtattccg aaatctatcc gtgaagctgg cgttcaggaa gcagacttcc
    19381 tggcgaacgt ggataaactg tctgaagatg cgttcgatga ccagtgcacc ggcgctaacc
    19441 cgcgttaccc gctgatctcc gagctgaaac agatcctgct ggatacctac tacggtcgtg
    19501 attatgtaga aggtgaaact gcagcgaaaa aagaagccgc tccggctaaa gctgagaaaa
    19561 aagcgaaaaa atccgcttaa tcagtagcgc tgtctggcaa tataaacggc cccttctggg
    19621 gccgtttttt tgtttaccca aagcaacttt tccataaacc gacagcatta gccttcatca
    19681 tatttgcgac gatgtataac gcctaaacac agggatattg tactttacag gtcacaagtc
    19741 aacgtcggtg cttaagagcc ctgtgaggcg tatagcggcg ttaaaaaact gccgagaagg
    19801 gtatatagcc cggaagaagt gcgtaaaacg aactgacagg ataaaagtgc cctgctcacc
    19861 ctgtcagtaa agaaattctt attaatcgtg gcgatgcctt tcctgaatag ccgttaatga
    19921 gccgacttgt aacgcctctt tatagtgttt acggcataca gaaatgtatc gttcattacc
    19981 accaattacc acctgctcac cttcgttata aggtctgcct gcttgatcaa gacgcagcac
    20041 catgcttgct ttacggccac aaaaacagat ggtttttaat tcaaccagtt tgtcggacca
    20101 tgccagtaag tattggctgc caataaataa ttcacctcga aaatcggtac gtaaaccata
    20161 acaaagtacg ggtatatcga gttgatcgac aacctccgat aattcatata cttgttgtct
    20221 ggttaaaaac tggcattcat caaccagtac gcaatgaatt gcctgctgtt catgttccgc
    20281 acgaatctca tcaaataatg atgaattttg gttaaataat tttgcaggcg atgacaaacc
    20341 tatacgcgaa ctgactttcc cggcaccaaa gcgatcatca atttctgccg tatatacgac
    20401 agtgcgcatg ccgcgttcct ggtaattgta tgaagattgc aacaatgctg tagacttacc
    20461 cgcattcatt gcggaatagt agaaatatag ctgtgccatc agccacaggc cctcaatgat
    20521 atgaaataaa gttggctgga gtttatcata attcgtcagt ttttcagctc aacagtatgc
    20581 acagaagtgg gtatatgcgt tctcccttac gaagccttgc ataatccttc tgagctatca
    20641 ttacaactgc ctcgcttgtt ataagcgggt aaatgactgc tggtaactat tcacaatctt
    20701 taacctgttg cgcaagtaat agccctctgt tgacctccag gagatagtgc aatactaagt
    20761 ccatgctctt attgcgactg ttctactttt catcattcgc ttaataggga attctcgtaa
    20821 acacaactaa tacagaagac tgaaaggtcg tcagcctacg ataatctccc cataaaatgt
    20881 gacatgaatc aggaagtttt aacctcacgt gctgcgaaat catcggtgta aatagggcta
    20941 tatgccgcgt cttttctggc taattttatg aaaagatatt tattggcggc acaaaataaa
    21001 gaacaatttt gaattcctta cattcctggc tattgcacaa ctgaatttaa ggctctatta
    21061 ttacctcaac aaaccacccc aatataagtt tgagattact acaatgagcg aagcacttaa
    21121 aattctgaac aacatccgta ctcttcgtgc gcaggcaaga gaatgtacac ttgaaacgct
    21181 ggaagaaatg ctggaaaaat tagaagttgt tgttaacgaa cgtcgcgaag aagaaagcgc
    21241 ggctgctgct gaagttgaag agcgcactcg taaactgcag caatatcgcg aaatgctgat
    21301 cgctgacggt attgacccga acgaactgct gaatagcctt gctgccgtta aatctggcac
    21361 caaagctaaa cgtgctcagc gtccggcaaa atatagctac gttgacgaaa acggcgaaac
    21421 taaaacctgg actggccaag gccgtactcc agctgtaatc aaaaaagcaa tggatgagca
    21481 aggtaaatcc ctcgacgatt tcctgatcaa gcaataatct tttgtagatt gcacttgctt
    21541 aaaatcccgc cagcggcggg attttttatt gtccggttta agacaattta ataagaataa
    21601 gctataaaaa aacggcgtcg attgctcaac gccgtttcgt ggataacacc gatacggatg
    21661 ttacttctta atgcccatct cttcttcaag ccaggcttta aattccgtgc caagggtgtt
    21721 atgacgaata ccgtattcaa cgaaggcctg catgtaacct aatttattac cgcagtcatg
    21781 gctcttccct ttcatatgat aggcttccac cgtttctttt tcgatcagca tatcaattgc
    21841 gtcggtgagc tgaatttcat caccagctcc cggaggggtt tttgccagca acggccaaat
    21901 atccgcgcta agtacgtaac gacccacaat agcgagatta gacggcgcaa catccgcttt
    21961 cggtttttct accacaccaa ccatcggtac gctttcaccc ggcgctaatt caacgccttt
    22021 gcaatccaca acgccatatg cggtcacatc agcaaccggt tcaaccatga tctggctatg
    22081 acccgtttca tcaaagcggc ggatcatctc tgccaggtta tcctgtgaca aatcggattc
    22141 atattcatcc agaataacat caggcaaaat aacagctacc ggttcatcac ccactaccgg
    22201 gtgagcacac aataccgcgt gtcccaggcc tttcgccaga ccctgacgaa cttgcataat
    22261 agttacgtgc ggcggacaaa tagactgcac ttcatcaagc agttgacgtt ttacacgttt
    22321 ttccagcatt gcttccagtt caaaactggt atcaaagtgg ttttcaatag agtttttaga
    22381 tgagtgtgta accagcacaa tttcagtaat gccagccgca atacattcat tcacgacgta
    22441 ttgaattaat ggcttatcga caagtggcag catctctttc gggatggctt tcgtcgccgg
    22501 caacatcctg gttcctaatc ccgcaacggg gataacggct tttttgactt tcgtattaat
    22561 ggcagccatt taaattctcc tggactgttc gtgttttgaa cgtgttcata tttctgtatc
    22621 gcatcccagt atatcagcac cccgaagggg ctaagttctg aaaaggaggc gagttagcat
    22681 aattaagaca attacttata cgaatggcga cgatagtacc accagccgac attagcaggt
    22741 aatgcaaatt tagcccgcgt tatcgtttgc tcattctgca gacaacatca agcgcagtcg
    22801 accaccggtt ccccatattt ggcattgcca ggcatcgcat cgctggctca attgattcaa
    22861 ataagcgtta cctaaagtgc ctaacggaac accattactg atttgcacct ggtgttcgcc
    22921 ggtatttaac gtcgcattca gacccgcaga aaccagaatg agatttttca gttcgcgatg
    22981 ataatagcca actaatagcg gaaactgccc cggcagattg gcctgacgaa gtaaatggtt
    23041 tacctgcttc aataacgcgc ccaactctgg caaccgttga ttttggtgtg caagctgttc
    23101 ctgtaataat ccgttaaaca atgcgcgtaa taacaaggca gcaagtacgc cattatgtcc
    23161 agctcgggtg acatcaaggc aataaaatgc cagatcgttt tccgaaagtg cggcaatatc
    23221 aagcaccagg ccgggtttgt ccgcggcaac caattgacga taattaaccc ggcaatggga
    23281 aatcacctgc tgaaccggcg gttgtagttc ctgtaataat ttcgccgctg cggcagggtt
    23341 atcaaccatt gcatcccagt cgcgaaaaag cctttcctct tcctcaacgc gcgaattaaa
    23401 catgctggga tagagacagg caaaaaccat ctcgcgcaag cgattcagat ctttaactgg
    23461 tttcagcaaa acatcttcaa cgcccagacg taacgctttg gcaatatctg ccatattttc
    23521 ggtggcagat atcaccagaa ccggtgtctg gtcacctctg ttgcgtatat gttccagcag
    23581 tttaagcccg ttcattcgtg gcatcgcgat atcacatatc atcaggtctg gagtgaaacc
    23641 tcccagcaac tcaagggcat ccaccccatc agccgccagt accgttgtcg ctcccaatga
    23701 ggaaaaccac gaatccagaa gcgagcgaaa taccggctca tcttcaacaa tgagaatctg
    23761 ttttccgacc aatggctgcg tcatgttctc tcccctgact ggctttactc aatagtggca
    23821 tgctattgcc acctgcgcct gtcagaatta acttaagtgt agataaaaat tctggtcaaa
    23881 tgttggtgcg taccaacggc aaaagttcgt ccattttctt ttccactgcc agctgtccgg
    23941 ccgcaatggc agcgtgcgcg cgatggaaat caagcgtaga tatttgcggg caaacaggtt
    24001 gaatcagaat atcgggcgga tcacctgcca tgcggttcct tttaaggcgg ttctccagca
    24061 cctggataga agtggtcata atctctgttg ccgttggcgc tgtcaccgcc cgacgtgtcg
    24121 ttatgctgcc taacctttct ttcagacgcg catgccacgg cagagaatca ccattctcgc
    24181 tattttcttc actgacatta aaggagagca aatcttgttg catcaaatga gcatcgtgct
    24241 gcaggtcaac cgctatcaca atatcagccc ccaatgcacg cgtgagggaa ataggaattg
    24301 ggttaacgac tgctccatca accagccagt agccgttatg tgcaacaggt gccatgagtc
    24361 ctggaatact gcatgatgcg cgaatagcaa gatggagatc gccttcagta aaccataatt
    24421 cacgtcccgt acttaaattg gtggcaacag ccgcaaagcg acgggaacaa ttttcgatct
    24481 ctgtttccgg cattatttcg cggtattgat tgaagacacg ctcgccgcgc agtaacccac
    24541 cgcgctgcca ggagagatcc atcaggcgta aaacatccca ataactgaaa gaggtcaccc
    24601 aatcttccag cgcagataat cgatcgcatg cataggcagc gcccaccagc gaaccaattg
    24661 aacatcctgc aacgatatca atttcaatac ccactttttt tagcgcatta ataacgccaa
    24721 tatgcgacca acctctcgcc gcgccagatc ccagcgccag ccctattttt atctttctca
    24781 ttattcccgc aagattcccc tggaatgcaa tcgtagccac atcgctactg ctcggttaac
    24841 atagtgctac tcaggcggtt aatacgccgt tattgtttcc agggagatta tttgtgtctc
    24901 agctttgtcc ctgtggtagt gctgtcgagt atagcctatg ttgccaccct tatgtgtctg
    24961 gtgaaaaggt tgcacctgat ccagaacatc tcatgcgttc gcgttactgc gcttttgtga
    25021 tgcaagacgc agattattta ataaagacct ggcatccctc ttgtggagca gcggcgttac
    25081 gtgccgaatt gatggccgga tttgcgcata ctgaatggtt gggattgacc gtatttgaac
    25141 attgttggca ggacgccgac aatatcggat ttgtcagttt tgttgctcga tttaccgaag
    25201 gtggtaaaac aggtgcaata gttgaacgtt cgcgattttt gaaagaaaac ggtcaatggt
    25261 actatattga cggtacacgt ccgcagtttg gtcgcaacga tccctgccct tgtggttcag
    25321 gtaaaaaatt taaaaagtgc tgcggccaat aatggttgac ggtacggttt agcaaacact
    25381 ctcaacaagg tttttccagc aatgcattca ctccaacgta aagttctgcg tactatttgt
    25441 ccggaccaaa aaggtctgat cgcacgtatt accaatattt gctacaagca cgagttaaat
    25501 atcgtacaga acaatgaatt tgttgatcac cgtaccgggc gcttttttat gcgcacggaa
    25561 ctggaaggga tttttaatga ttccaccctg ctggcggatc tcgatagcgc attgccagaa
    25621 ggctccgtgc gtgagctgaa tcctgccggt cgtcgccgga tagtgattct ggtcactaaa
    25681 gaagcgcatt gccttggcga tttgttgatg aaagccaatt acggcggcct ggatgtcgaa
    25741 atcgcggcag ttattggtaa ccacgatact ttacgttctc tggttgagcg ttttgatatt
    25801 ccgtttgagc tggtaagcca tgaagggtta agccgcaacg agcacgatca aaagatggcg
    25861 gacgccattg atgcttatca acctgactat gtggtgctgg cgaagtatat gcgggtatta
    25921 acgccggaat ttgtggcacg cttcccgaat aaaatcatca atattcacca ttcattcctg
    25981 cctgcgttta tcggcgcacg tccttatcac caggcctatg aacgtggtgt gaagattatt
    26041 ggcgcaaccg ctcactatgt gaatgacaat ctggacgaag gcccaatcat catgcaggac
    26101 gttattcatg tcgatcatac ctacacagct gaagatatga tgcgcgcagg tcgtgacgtc
    26161 gagaaaaacg tcttaagtcg tgcgctatac aaagtactgg cacagcgcgt ctttgtttac
    26221 ggtaatcgga cgattattct ttaatcgcca gcaaaaataa ctggttacct ttaatccgtt
    26281 acggatgaaa attacgcaac cagttcattt ttctcaacgt aacactttac agcggcgcgt
    26341 catttgatat gatgcgcccc gcttcccgat aagggagcag gccagtaaaa agcattaccc
    26401 cgtggtgggg ttcccgagcg gccaaaggga gcagactgta aatctgccgt catcgacttc
    26461 gaaggttcga atccttcccc caccaccatc actttcaaaa gtccgtgaac tctcaaacga
    26521 atccgcgatt aaatattctg cccatgcggg gaaggatgag aagcctcgac caaggttcga
    26581 ctcgagcgcc agcgagagag cgttgccgca ggcaacgacc cgaagggcga agcgcgcagc
    26641 gttgagtaat ccttccccca ccaccatcac ttccttaaat aatcaaaacc tgttactccg
    26701 agctaatttt gcccgatggc accacgttta ccgggcctac aatatcctcc cctgtaggtc
    26761 ggataagcga agcgcatccg acaactcacc ccgcaccgtg cccataaaaa aaccccgccg
    26821 aagcagggtc tatgtgaact aaaattcgct tagtgacgag cgcgcaccag ctggtactta
    26881 cgtgtcagat actccaccgg tacgctccag atgtgtacca gacgcgagaa cgggaacagc
    26941 aggaataacg tcatccccag caccaggtgc agacggaaga taaacgccac accatcgagg
    27001 tgttgagaag cgccaccgtg gaaggtcacc accgactgcg cccagccaac cagtttcatc
    27061 atctcgctac cgtccatatg ctgagcggag aacggaatgg tcaacaggcc cagcgcgcac
    27121 tggataacga gcagcgacag gatcaggata tccgctccgg tagtggttgc acgcacgcgt
    27181 gggctgaaca gacgacgctt cagcaacagc acgccgccaa tcagacacag cacgccgctg
    27241 gcaccaccag caaacatcgc cattttctgt ttcacttcaa tcggcagcca ggcttcatac
    27301 atccagtgcg gcgtcagcat accgaagaag tgaccaacaa aaatccccag aataccgata
    27361 tggaacaggt tcgacgccag gttcatccct ttgcgatcca gcatctggct ggacgccgcg
    27421 cgccaggtgt actgcccgta gtcataacgc agccagctac caatcaggaa gaccgccccg
    27481 gctatgtacg ggtagatatc aaagaagaac atattcagga attgcattag tgctgtcctc
    27541 cggtggtgat attcagatat tgcggcgcga cggcaccggc aaagcgacgc tgatgagcag
    27601 tgattgctga atcaccgcag cctttgtcag caaagaattt aacctgctct tcttcccaga
    27661 cagcatccag cgcctgcggc gtatcatcgc gcgcttcgtc ggcaattttt tccgccactt
    27721 tgtcgctgtc gatagcggta ttggccaatt tcagcagcag atcaaacatc acggcataac
    27781 ggctttcacg ctgttgcaga cgcgcgctca gcaatgccag aatcggcgcg atatctttca
    27841 aaccttccac ggcttcgctt tgcggcagct gcgacaggta ctccagatac agcggcagat
    27901 ggtccggtaa ttcgcggctg tttaactgca agccgtgctg ctcgtactgc gccagcaggt
    27961 ccaccatcgc ctggccgcgg tcacgggatt caccgtgaac atgttcaaat agcaacagtg
    28021 acgtggcgcg gccacggtcg aacagttcgc tgtactgggc ctgggcatcg agcggatcca
    28081 tcgccgttaa atcgcgcagg aaaatgccca gcgcatgggc atcttctttc gacagatttt
    28141 tcgacgcagc aatcgcctca aacatctctt gttgatgctg ccataaggca gcatccggat
    28201 attcaaggag acgcgataca atcacgagtt cgatcatgga tgcggctccg ttttgctggt
    28261 cacatcgatg gcatcgatac gacggctgtt gaacagattg aatttggtat ctgaaccgtg
    28321 gcagccatca ccaaaggtaa agccgcagcc atttttctcc gggaaggctt cccgtgccag
    28381 ttcacgatga ctactcggca ccacaaagcg atcttcgtag ttagcaatcg ccagataacg
    28441 gtacatctcc tgtgcctggg cttcggtcag accgacctct tccagcgcac gggtatcaac
    28501 tttaccgtca acggtttcag cacgtttgta atgacgcatc gccagcatac gtttcagtgc
    28561 gcgcagtacc ggtttggtat caccggcggt cagcagattc gccagatact gtaccggaat
    28621 acgcaagctt tcgacgtctg gcagaatgcc gttgctaccc agctcacccg cgtctgccgc
    28681 agactgaatc ggagacagag gcggcacgta ccagaccatc ggcagtgtgc gatattctgg
    28741 atgcagcggc agcgccagtt tccattccat tgccatttta taaaccggcg actgctgtgc
    28801 ggcttcaata acgctcagcg gaataccgtc tttaatcgcc tgctcgatga ctttcggatc
    28861 gttcggatcg aggaacacct ccagctgacg ctggtaaaga tctttctcgt tctcggtgct
    28921 ggctgcacgt tcaatcgcgt cggcatcgta cagcagcacg ccaagataac ggatacgacc
    28981 gacacaggtt tctgagcaca cggtcggctg acccgcttca atacgcggat agcagaagat
    29041 gcacttctca gacttaccgc tcttccagtt gaagtagatt tttttgtacg ggcatccggt
    29101 gatgcacata cgccagccac ggcatttatc ctggtcgatc aggacgatgc catcttcttc
    29161 acgcttgtaa atcgcaccgc tcgggcaggt cgccacacat gccgggttca ggcagtgttc
    29221 gcacaggcgc ggcaaataca tcataaaggt gttttcgaac tggctataca tcgccttctg
    29281 gatgttgtcg aagttcttgt ctttcgccag cttgtcaaac tcaccgccca ggtcatcttc
    29341 ccagttcggc cctttttcga ttttcgccat ccgttcgccg gtaatcagcg aacgcggacg
    29401 ggcaatcggc tgcgatttgc tgccttccgg cgcggtatgc aggttctgat agtcaaaatc
    29461 gaacggctcg taataatcgt cgatccccgg cagatgcggg ttagcgaaga ttttacccag
    29521 cagcatggca cggttaccca tgcgcggctg cagtttgccg ttgattttac ggatccagcc
    29581 gcctttgtat ttttcctggt tttcccagtc agtcgggaag ccctggcccg gcttggtttc
    29641 cacgttgttg aaccacgcgt attccacgcc ttcacggctg gtccagacgt ttttacaggt
    29701 aactgaacag gtgtggcagc cgatgcactt atcgagattc agcaccatgc cgacttgtga
    29761 acgaattttc attttacgct ctcctgtacc tggtcattgc cttcgccatc taaccagtca
    29821 atgttcttca tcttacgcac tacaacaaac tcatcgcggt tagaacctac ggtgccgtag
    29881 tagttaaagc cgtatgccag atgggcatag ccgccgatca tatgcgtcgg tttcggcgtg
    29941 atacgggtga ccgagttatg gataccacca cgctgttggg taatttccga accaggcagg
    30001 ttaacgatac gttcctgcgc gtggtacatc atggtcatcc ctgccggaac acgctggctg
    30061 acaaccgcac gggcagtcag agcaccgttg ctgttgaata cttcaatcca gtcgttatcg
    30121 gcgataccca gatctttggc atcggcttca ctcaaccaga ccaccggacc accgcgacct
    30181 aaagtcagca tcagcaggtt gtcgctgtag gtggagtgga taccccactt ctggtgcggc
    30241 gtcaggaagt tgagcgcttt ttccgggttg ccgttggatt tctggcctat cacttctttc
    30301 accgaacggg tgtcgatcgg cggacgataa accagcaggc tttcaccgaa atcacgcatc
    30361 cactggtgat cctgatacag ttgctgacga ccagtgagcg tacgccatgg gatcagctcg
    30421 tgaacgttgg tgtaaccggc gttgtaagaa acgtgttcat cttccagacc agaccaggtc
    30481 gggctggaga taattttgcg cggctgtgcc tgaatatcgc ggaagcggat cttctcgtct
    30541 tctttattca gcgccagatg cgtatggtca cgaccggtaa attcgctcag ggcagcccag
    30601 gctttcacgg ctacctgacc gttggtttcc ggtgccagtg tcaggatcat ctctgccgca
    30661 tcaattgcgg tgttcagcat cggctggcct ttcgccggac cttccgcttt ggtgtagttg
    30721 agcttacgca gcagatccat ctcgctctgg gtgttccagg caatcccttt accgccatta
    30781 ccgattttct ccatcagcgg gccgatagag gtaaagcgtt cgtaagtcgc cggataatca
    30841 cgctctacga ccataatgtg tggcgcggtt ttacctggga tcaggtcgca ctcgcctttt
    30901 ttccagtctt tcacatccag cggctgcgcc agttcagcgg cagagtcatg ctggataggc
    30961 agcgtgacga tgtcggtttc tttacccaga tggccgacgc acacttcgga gaatttcttc
    31021 gcgatggctt tgtagatttc ccagtcgctt ttcgcttccc aggccggatc gaccgccgca
    31081 gacagcgggt gaataaacgg atgcatatcc gaagtattca tgtcgtcttt ttcgtaccag
    31141 gtcgccgtcg gcaaaatgat gtcggaatag agacaggtgc tcgacagacg gaagtccagc
    31201 gtaaccacca gatccagctt gccttccaga ccattgtcct gccagtccac ttcttccggc
    31261 ttcacgccgc cctgttgccc cagatcttta ccctggatac cgtgctccgt ccccagcagg
    31321 tacttgagca taaactcatg acctttaccg gaagaaccga gcaggttaga acgccagatg
    31381 aacaggttgc gcgggtggtt tttaccgttt tctggttgtt ctgccgcaaa acggatggaa
    31441 ccctctttca gggatttcac cgtatagtcc accggattca tcccggcttt ttccgcttcg
    31501 ccagcgatag tcagcgggtt agtgcctaac tgcggtgcag acggcagcca gcccatgcgt
    31561 tccgcacgga cgttaaagtc gatcaagtgt ccggtatagc gggatttgtc cgccatcggt
    31621 gacagcaact cttccgccgt gacggtttca taacgccact ggctggagtg gttatagaaa
    31681 taagaagtgc tgttcatgtg acgcgccgga cgctgccagt caagggcaaa cgccagcggc
    31741 tgccagccgg tttgcggacg cagtttttcc tgacctacat agtgcgccca gccgcccccg
    31801 ctctgaccga cacagccgca gaaaatcagc atgttgatca gaccacgata gttcatatcg
    31861 aggtgatacc agtggttcag ccccgcaccg acgataatca tcgaacgacc gtgcgtttta
    31921 tcagcgttat cggcaaattc acgggcgatg cgaataatct ggctgcgaga aacgccggta
    31981 atctgctcgg cccaggccgg ggtataagct ttcacatcgt catagctggt tgcacagtta
    32041 acgtcgttca ggccacgttc cagaccgtag tttgccagcg tcagatcata aacggtggtc
    32101 accagggcgg tgctgccatc agccagttgc aggcgtttca ccggcagttt gtgcagcagc
    32161 acgttttcca gttccacttt gttgaagtgt tccgtgccgt cgccaccaaa gtacgggaag
    32221 cctacctcag cgatctcatc ctggctaccc agcaggctca gttgcagctc ggtttcttcg
    32281 ccagttttgc cgtcgcgctg ctcaagattc catttgccct tctcgcccca gcggaagcca
    32341 atagaaccgt tcggcgcaac catttcgcca ttggtattaa aggcgacagt tttccattcc
    32401 ggattgtttt cctggcccag cgcatcaacc agatcagcag cgcgcagcat acgacctgca
    32461 gcgtagtaac cgtcgcgttc ttccagcatc accagcatcg gcatgtcggt gtagcgacgc
    32521 acatagtcgg tgaaatactg gcttgggttg tcgaggtgga attcacgcag cattacgtgg
    32581 cccatcgcca gcgccattgc cgcatcggtg ccctgtttcg gtgccagcca cagatcgcac
    32641 agtttggcga tttcagcgta gtctggtgtg acggcaacag ttttggtccc tttgtaacgc
    32701 acttcagtaa agaagtgagc atccggggta cgcgtctgcg gcacgtttga cccccaggcg
    32761 atgatgtagc tggagttgta ccagtcagca gattccggta cgtcagtttg ctcgccccag
    32821 gtttgcggag acgcaggagg caagtcgcag taccagtcgt agaagcttaa gcaagtaccg
    32881 ccaatcagcg agagatagcg tgcacccgat gcgtaagaaa ccatcgacat tgccggaatt
    32941 ggcgagaaac cagcaacacg gtccgggccg tagtttttga tggtgtaaac gttagatgcg
    33001 gcgatcagtt cgttcacctc ctgccaggaa gaacgaacaa atccaccgcg tccacgcgcc
    33061 tgcttaaagc ttttcgcttt atcggcgtct tcaatgatag aagcccatgc ctcaaccgga
    33121 tcgctatgca gcgccttcgc ttcacgccac attttcatca ggcgtttgcg catcatcggg
    33181 tatttcaggc ggttggcact gtaaagatac caggagtagc tggcaccgcg cgggcagccg
    33241 cgaggttcat ggtttggcag atccggacgg gtacgcggat agtcagtctg ctgggtttcc
    33301 caggtgacca gaccgttttt gacgtagatt ttccagctgc aggagccggt gcagtttacc
    33361 ccgtgggtag agcggacgat tttgtcatgc tgccaacgct ggcgatatcc atcctcccag
    33421 tcacggttgg tattgagaag ctggccatgc ccatcggcaa aggtttcacc cttctgtttg
    33481 aagtagcgaa accggtccag gaatttactc atcggttttc tcctgtggga gcctgtcggc
    33541 cctctgataa atcgacattg ctaatgttta agggcaaggt aacgctctga aacagcgtgg
    33601 gaattgataa cgatcaagag tgatggggat gaaaaataaa gtaaattcct aagatacccc
    33661 tttaggataa ttaacagaca ccacataaca gactgtaaat t
//
LOCUS       DAPGUL010000044        33175 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.044, whole genome shotgun sequence.
ACCESSION   DAPGUL010000044 DAPGUL010000000
VERSION     DAPGUL010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33175)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33175)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33175
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.044"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(382..476)
                     /locus_tag="RHX21_002236"
     tRNA            complement(382..476)
                     /locus_tag="RHX21_002236"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(440..442),aa:Sec,seq:tca)
     gene            769..2151
                     /locus_tag="RHX21_002237"
     CDS             769..2151
                     /locus_tag="RHX21_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418114.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide family
                     transporter"
                     /protein_id="HDV1987408.1"
                     /translation="MKSEVLSVKEKIGYGMGDAASHIIFDNVMLYMMFFYTDIFGIPA
                     GFVGTMFLVARALDAISDPCMGLLADRTRSRWGKFRPWVLFGALPFGIVCVLAYSTPD
                     LSMNGKMIYAAITYTLLTLLYTVVNIPYCALGGVITNDPTQRISLQSWRFVLATAGGM
                     LSTVLMMPLVNLIGGDNKPLGFQGGIAVLSVVAFMMLAFCFFTTKERVEAPPTTTSMR
                     EDLRDIWQNDQWRIVGLLTIFNILAVCVRGGAMMYYVTWILGTPEVFVAFLTTYCVGN
                     LIGSALAKPLTDWKCKVTIFWWTNALLAVISLAMFFVPMQASITMFVFIFVIGVLHQL
                     VTPIQWVMMSDTVDYGEWCNGKRLTGISFAGTLFVLKLGLAFGGALIGWMLAYGGYDA
                     AEKAQNSATISIIIALFTIVPAICYLLSAIIAKRYYSLTTHNLKTVMEQLAQGKRRCQ
                     QQFTSQEVQN"
     gene            2161..4479
                     /gene="yicI"
                     /locus_tag="RHX21_002238"
     CDS             2161..4479
                     /gene="yicI"
                     /locus_tag="RHX21_002238"
                     /EC_number="3.2.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HDV1987409.1"
                     /translation="MKISDGNWLIQPGLNLIHPLQVFEVEQQDNEMVVYAAPRDVRER
                     TWQLDTPLFTLRFFSPQEGIVGVRIEHFQGALNNGPHYPLNILQDVKVTIENTERYAE
                     FKSGNLSARVSKGEFWSLDFLRNGERITGSQVKNNGYVQDTNNQRNYMFERLDLGVGE
                     TVYGLGERFTALVRNGQTVETWNRDGGTSTEQAYKNIPFYMTNRGYGVLVNHPQCVSF
                     EVGSEKVSKVQFSVESEYLEYFVIDGPTPKAVLDRYTRFTGRPALPPAWSFGLWLTTS
                     FTTNYDEATVNSFIDGMAERNLPLHVFHFDCFWMKAFQWCDFEWDPLTFPDPEGMIRR
                     LKAKGLKICVWINPYIGQKSPVFKELQEKGYLLKRPDGSLWQWDKWQPGLAIYDFTNP
                     DACKWYADKLKGLVAMGVDCFKTDFGERIPTDVQWFDGSDPQKMHNHYAYIYNELVWN
                     VLKDTVGEEEAVLFARSASVGAQKFPVHWGGDCYANYESMAESLRGGLSIGLSGFGFW
                     SHDIGGFENTAPAHVYKRWCAFGLLSSHSRLHGSKSYRVPWDYDDESCDVVRFFTQLK
                     CRMMPYLYREAARANARGTPMMRAMMMEFPDDPACDYLDRQYMLGDNVMVAPVFTEAG
                     DVQFYLPEGRWTHLWHNDELDGSRWHKQQHSFLSLPIYVRDNTLLALGNNDQRPDYVW
                     HEGTAFHLFNLQDGHEAVCEVPATDGSVIFTLKAARTGNTITVTGAGEAKNWTLCLRN
                     VVKVNGLQDGSQAESEQGLVVKPQGNALTITL"
     gene            complement(4532..6241)
                     /locus_tag="RHX21_002239"
     CDS             complement(4532..6241)
                     /locus_tag="RHX21_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HDV1987410.1"
                     /translation="MKFIGKLLLYILIALLVVIAGLYFLLQTRWGAEHISAWVSENSD
                     YHLAFGAMDHRFSAPSHIVLENVTFGRDGQPATLVAKSVDIALSSRQLTEPRHVDTIL
                     LENGTLNLTDQTAPLPFKADRLQLRDMAFNSPNSEWKLSAQRVNGGVVPWSPKAGKVL
                     GTKAQIQFSAGSLSLNDVPATNVLIEGSIDNDRVTLTNLGADIARGTLTGNAQRNADG
                     SWQVENLRMADIRLQSEKSLTDFFAPLRSVPSLQIGRLEVIDARLQGPDWAVTDLDLS
                     LRNMTFSKDDWQTQEGKLSMNASEFIYGSLHLFDPIINAEFSPQGVALRQFTSRWEGG
                     MVRTSGNWLRDGKTLILDDVAIAGLEYTLPKNWQQLWIETTPGWLNSLQLKRFSASRN
                     LIIDIDPDFPWQLTALDGYGANLTLVTDHKWGVWSGSANLNAAAATFNRVDVRRPSLA
                     LTANSSTVNISELSAFTEKGILEATASVSQTPQRQTHISLNGRGVPVNILQQWGWPKL
                     PLTGDGNIQLTASGDIQANVPLKPTVSGQLHAVNAAKQQVTQTMNAGIVSSGEVTSTE
                     PVR"
     gene            complement(6362..7753)
                     /gene="xanP"
                     /locus_tag="RHX21_002240"
     CDS             complement(6362..7753)
                     /gene="xanP"
                     /locus_tag="RHX21_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine/proton symporter XanP"
                     /protein_id="HDV1987411.1"
                     /translation="MSVSTLESENAQPVAQTQNSELIYRLEDRPPLPQTLFAACQHLL
                     AMFVAVITPALLICQALGLPAQDTQHIISMSLFASGVASIIQIKAWGPVGSGLLSIQG
                     TSFNFVAPLIMGGTALKTGGADVPTMMAALFGTLMLASCTEMVISRVLHLARRIITPL
                     VSGVVVMIIGLSLIQVGLTSIGGGYAAMSDNTFGAPKNLLLAGVVLALIILLNRQRNP
                     YLRVASLVIAMAAGYALAWFMGMLPESNEPMTQELIMVPTPLYYGLGIEWSLLLPLML
                     VFMITSLETIGDITATSDVSEQPVSGPLYMKRLKGGVLANGLNSFVSAVFNTFPNSCF
                     GQNNGVIQLTGVASRYVGFVVALMLIVLGLFPAVSGFVQHIPEPVLGGATLVMFGTIA
                     ASGVRIVSREPLNRRAILIIALSLAVGLGVSQQPLILQFAPEWLKNLLSSGIAAGGIT
                     AIVLNLIFPPEKQ"
     gene            8033..9238
                     /gene="gltS"
                     /locus_tag="RHX21_002241"
     CDS             8033..9238
                     /gene="gltS"
                     /locus_tag="RHX21_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HDV1987412.1"
                     /translation="MFHLDTLATLVAATLTLLLGRKLVHSVSFLKKYTIPEPVAGGLL
                     VALALLVLKKSMGWEVNFDMSLRDPLMLAFFATIGLNANIASLRAGGRVVGIFLIVVV
                     GLLVMQNAIGIGMASLLGLDPLMGLLAGSITLSGGHGTGAAWSKLFIERYGFTNATEV
                     AMACATFGLVLGGLIGGPVARYLVKHSTTPNGIPDDQEVPTAFEKPDVGRMITSLVLI
                     ETIALIAICLTVGKIVAQLLAGTAFELPTFVCVLFVGVILSNGLSMMGFYRVFERAVS
                     VLGNVSLSLFLAMALMGLKLWELASLALPMLAILVVQTIFMALYAIFVTWRMMGKNYD
                     AAVLAAGHCGFGLGATPTAIANMQAITERFGPSHMAFLVVPMVGAFFIDIVNALVIKL
                     YLMLPIFAG"
     gene            9241..10107
                     /locus_tag="RHX21_002242"
     CDS             9241..10107
                     /locus_tag="RHX21_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312555.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987413.1"
                     /translation="MKKRRKEPETLREHCRHIFGDEPPVLCVWETEFDYADAELKALA
                     AKEWQQISVWDLSAYYVLNLVYNEPMQIELFRYLFPLCLAQWHETVLAGGYGDHFEES
                     LMKALCRPYLWQEMMNASQRQQVRQFLLDTALQRMDNERGFNNVLCWLAVFNTLGGAA
                     PLIHSLWSRWWALDTPGKAVCAIQYAAHLIYPIEANPLWSQEWIGWGHPLGHKDGWSS
                     DNRAFLRQMLTPEMIVAGVQAAAEILRGEPEGAMAARIAQDAYEAMDILTIQIEDLLR
                     DLSCDESGHALE"
     gene            complement(10092..12173)
                     /gene="recG"
                     /locus_tag="RHX21_002243"
     CDS             complement(10092..12173)
                     /gene="recG"
                     /locus_tag="RHX21_002243"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HDV1987414.1"
                     /translation="MKGRLLDAVPLSSLTGVGAALSNKLAKINLHTVQDLLLHLPLRY
                     EDRTHLYPIGELLPGVYATVEGEVLNCNISFGGRRMMTCQISDGSGILTMRFFNFSAA
                     MKNSLATGRRVLAYGEAKRGKYGAEMIHPEYRVQGDLSTPELQETLTPVYPTTEGVKQ
                     ATLRKLTDQALDLLDTCAIEELLPPELSQGMMTLPEALRTLHRPPPTLQLSDLETGQH
                     PAQRRLILEELLAHNLSMLALRAGAQRFHAQPLSANDTLKNKLLAALPFKPTGAQARV
                     VAEIERDMALDVPMMRLVQGDVGSGKTLVAALAALRAIAHGKQVALMAPTELLAEQHA
                     NNFRNWFAPLGIEVGWLAGKQKGKARLAQQEAIASGQVQMIVGTHAIFQEQVQFNGLA
                     LVIIDEQHRFGVHQRLALWEKGQQQGFHPHQLIMTATPIPRTLAMTAYADLDTSVIDE
                     LPPGRTPVTTVAIPDTRRTDIIDRVRHACITEGRQAYWVCTLIEESELLEAQAAEATW
                     EELKLALPELNVGLVHGRMKPVEKQAVMASFKQGELHLLVATTVIEVGVDVPNASLMI
                     IENPERLGLAQLHQLRGRVGRGAVASHCVLLYKTPLSKTAQIRLQVLRDSNDGFVIAQ
                     KDLEIRGPGELLGTRQTGNAEFKVADLLRDQAMIPEVQRLARHIHERYPQQAKALIER
                     WMPETERYSNA"
     gene            complement(12179..12868)
                     /gene="trmH"
                     /locus_tag="RHX21_002244"
     CDS             complement(12179..12868)
                     /gene="trmH"
                     /locus_tag="RHX21_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(18)-2'-O)-methyltransferase
                     TrmH"
                     /protein_id="HDV1987415.1"
                     /translation="MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVG
                     VHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNA
                     VDFREIDYTRPTCILMGQEKTGITQEALALADQDIIIPMIGMVQSLNVSVASALILYE
                     AQRQRQNAGMYLRENSMLPEAEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEAD
                     ADWWATMQAAG"
     gene            complement(12875..14983)
                     /gene="spoT"
                     /locus_tag="RHX21_002245"
     CDS             complement(12875..14983)
                     /gene="spoT"
                     /locus_tag="RHX21_002245"
                     /EC_number="3.1.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional GTP
                     diphosphokinase/guanosine-3',5'-bis pyrophosphate
                     3'-pyrophosphohydrolase"
                     /protein_id="HDV1987416.1"
                     /translation="MYLFESLNQLIQTYLPEDQIKRLRQAYLVARDAHEGQTRSSGEP
                     YITHPVAVACILAEMKLDYETLMAALLHDVIEDTPATYQDMEQLFGKSVAELVEGVSK
                     LDKLKFRDKKEAQAENFRKMIMAMVQDIRVILIKLADRTHNMRTLGSLRPDKRRRIAR
                     ETLEIYSPLAHRLGIHHIKTELEELGFEALYPNRYRVIKEVVKAARGNRKEMIQKILS
                     EIEGRLQEAGIPCRVSGREKHLYSIYCKMVLKEQRFHSIMDIYAFRVIVNDSDTCYRV
                     LGQMHSLYKPRPGRVKDYIAIPKANGYQSLHTSMIGPHGVPVEVQIRTEDMDQMAEMG
                     VAAHWAYKEHGETSTTAQIRAQRWMQSLLELQQSAGSSFEFIESVKSDLFPDEIYVFT
                     PEGRIVELPAGATPVDFAYAVHTDIGHACVGARVDRQPYPLSQPLTSGQTVEIITAPG
                     ARPNAAWLNFVVSSKARAKIRQLLKNLKRDDSVSLGRRLLNHALGGSRKLNEIPQENI
                     QRELDRMKLATLDDLLAEIGLGNAMSVVVAKNLQHGDASIPPATQSHGHLPIKGADGV
                     LITFAKCCRPIPGDPIIAHVSPGKGLVIHHESCRNIRGYQKEPEKFMAVEWDKETAQE
                     FITEIKVEMFNHQGALANLTAAINTTTSNIQSLNTEEKDGRVYSAFIRLTARDRVHLA
                     NIMRKIRVMPDVIKVTRNRN"
     gene            complement(15002..15277)
                     /gene="rpoZ"
                     /locus_tag="RHX21_002246"
     CDS             complement(15002..15277)
                     /gene="rpoZ"
                     /locus_tag="RHX21_002246"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013511051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HDV1987417.1"
                     /translation="MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEEND
                     KTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR"
     gene            complement(15332..15955)
                     /gene="gmk"
                     /locus_tag="RHX21_002247"
     CDS             complement(15332..15955)
                     /gene="gmk"
                     /locus_tag="RHX21_002247"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HDV1987418.1"
                     /translation="MAQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQP
                     RPGEVHGEHYFFVNHDEFKEMISRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLD
                     IDWQGAQQIRQKMPHARSIFILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEMSHY
                     AEYDYLIVNDDFDTALTDLKTIIRAERLRMSRQKQRHDALISKLLAD"
     gene            16213..17895
                     /gene="ligB"
                     /locus_tag="RHX21_002248"
     CDS             16213..17895
                     /gene="ligB"
                     /locus_tag="RHX21_002248"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312549.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigB"
                     /protein_id="HDV1987419.1"
                     /translation="MKVWMAILISILCWQSSVWAVCPAWSPARAQEEISRLQQQIKQW
                     DDDYWKEGKSEVEDGVYDQLSARLTQWQRCFGSEPRDVMMPPLNGAVMHPVAHTGVRK
                     MVDKNALSLWMRERSDLWVQPKVDGVAVTLVYRDGKLNKAISRGNGLKGEDWTQKVSL
                     ISAVPQTVSGPLANSTLQGEIFLQREGHIQQQMGGINARAKVAGLMMRQDDSDTLNSL
                     GVFVWAWPDGPQLMTDRLKELATAGFTLTQRYTRAVKNADEVARVRNEWWKAKLPFVT
                     DGVVVRGAKEPESRHWLPGQAEWLVAWKYQPVAQVAEVKAIQFAVGKSGKISVVASLA
                     PVMLDDKKVQRVNIGSVRRWQEWDIAPGDQILVSLAGQGIPRIDDVVWRGAERTKPTP
                     PENRFNSLTCYFASDVCQEQFISRLVWLGSKQVLGLDGIGEAGWRALHQTHRFEHIFS
                     WLLLTPEQLQNTPGIAKSKSAQLWHRFNLARKQPFTRWVMAMGIPLTRAALNASDERS
                     WSQLLFSTEQFWQQLPGTGSGRARQVIEWKENAQIKKLGSWLAAQQITGFEP"
     gene            complement(17892..18509)
                     /locus_tag="RHX21_002249"
     CDS             complement(17892..18509)
                     /locus_tag="RHX21_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312548.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HDV1987420.1"
                     /translation="MLLHILYLVGITAEAMTGALAAGRRRMDTFGVIIIATATAIGGG
                     SVRDILLGHYPLGWVKHPEYVIIVATAAVLTTIVAPVMPYLRKVFLVLDALGLVVFSI
                     IGAQVALDMGHGPIIAVVAAVTTGVFGGVLRDMFCKRIPLVFQKELYAGVSFASAVLY
                     IALQHYVSNHDVVIISTLVFGFFARLLALRLKLGLPVFYYSHEGH"
     gene            complement(18801..19625)
                     /gene="dinD"
                     /locus_tag="RHX21_002250"
     CDS             complement(18801..19625)
                     /gene="dinD"
                     /locus_tag="RHX21_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312547.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein D"
                     /protein_id="HDV1987421.1"
                     /translation="MNEHHQPFEEIRHYGTEGQEFWSARELAPLLDYRDWRNFQKVLA
                     RATQACEASNQAASDHFVETTKMVVLGSGAQRELEDVHLSRYACYLVVQNGDPAKPVI
                     AAGQTYFAIQTRRQELADDEAFRQLREDEKRLFLRNELKEHNKQLVEAAQQAGVATAI
                     DFAIFQNHGYRGLYGGLDQKAIHQRKGLKKSQKILDHMGSTELAANLFRATQTEEKLK
                     RDGVNSKQQANTTHFDVGSKVRQTIQELGGTMPEELPTPQVSIKQLENSVKITEKK"
     gene            complement(19846..20709)
                     /locus_tag="RHX21_002251"
     CDS             complement(19846..20709)
                     /locus_tag="RHX21_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HDV1987422.1"
                     /translation="MIRSMTAYARREIKGEWGSATWEMRSVNQRYLETYFRLPEQFRS
                     LEPVVRERIRSRLTRGKVECTLRYEPDVSAQGELILNEKLAKQLVTAANWVKMQSDEG
                     EINPVDILRWPGVMAAQEQDLDAIAAEILAALDGTLDDFIVARETEGQALKALIEQRL
                     EGVTAEVVKVRAHMPEILQWQRERLVAKLEDAQVQLENNRLEQELVLLAQRIDVAEEL
                     DRLEAHVKETYNILKKKEAVGRRLDFMMQEFNRESNTLASKSINAEVTNSAIELKVLI
                     EQMREQIQNIE"
     gene            20836..21552
                     /gene="rph"
                     /locus_tag="RHX21_002252"
     CDS             20836..21552
                     /gene="rph"
                     /locus_tag="RHX21_002252"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006803115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HDV1987423.1"
                     /translation="MRPAGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIE
                     EGVPRFLKGQGQGWITAEYGMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAV
                     DLKALGEFTITLDCDVLQADGGTRTASITGACVALADALQKLVENGKLKTNPMKGMVA
                     AVSVGIVNGEAVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLTLL
                     ALARGGIESIVATQKAALAN"
     gene            21618..22259
                     /gene="pyrE"
                     /locus_tag="RHX21_002253"
     CDS             21618..22259
                     /gene="pyrE"
                     /locus_tag="RHX21_002253"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HDV1987424.1"
                     /translation="MKPYQRQFIEFALGKQVLKFGEFTLKSGRKSPYFFNAGLFNTGR
                     DLALLGRFYAEALVDSGLEFDLLFGPAYKGIPIATTTAVALAEHHDLDLPYCFNRKEA
                     KDHGEGGNLVGSALQGRVMLVDDVITAGTAIRESMEIIQANGATLAGVLISLDRQERG
                     RGEISAIQEVERDYNCKVISIITLKDLIAYLEEKPEMAEHLAAVKAYREEFGV"
     gene            complement(22296..22892)
                     /gene="slmA"
                     /locus_tag="RHX21_002254"
     CDS             complement(22296..22892)
                     /gene="slmA"
                     /locus_tag="RHX21_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion factor SlmA"
                     /protein_id="HDV1987425.1"
                     /translation="MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVS
                     EAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKDTTARLRLIVLLLLGFGERN
                     PGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYTTDETLLAS
                     QILAFCEGMLSRFVRSEFKYRPTDDFDARWPLIAAQLQ"
     gene            complement(22999..23457)
                     /gene="dut"
                     /locus_tag="RHX21_002255"
     CDS             complement(22999..23457)
                     /gene="dut"
                     /locus_tag="RHX21_002255"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HDV1987426.1"
                     /translation="MMKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLDDAVELA
                     PGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVW
                     NRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ"
     gene            complement(23435..24655)
                     /gene="coaBC"
                     /locus_tag="RHX21_002256"
     CDS             complement(23435..24655)
                     /gene="coaBC"
                     /locus_tag="RHX21_002256"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418096.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HDV1987427.1"
                     /translation="MSLAGKKIVLGVSGGIAAYKTPELVRRLRDRGADVRVAMTEAAK
                     AFITPLSLQAVSGYPVSDSLLDPAAEAAMGHIELGKWADLVILAPATADLIARVAAGM
                     ANDLVSTICLATPAPVAVLPAMNQQMYRAAATQHNLEVLASRGLLIWGPDSGSQACGD
                     IGPGRMLDPLTIVDMAVAHFSPVNDLKHLNIMITAGPTREPLDPVRYISNHSSGKMGF
                     AIAAAAARRGANVTLVSGPVSLPTPPFVKRVDVMTALEMEAAVNASVQQQNIFIGCAA
                     VADYRAATVAPEKIKKQATQGDELTIKMVKNPDIVAGVAALKDHRPYVVGFAAETNNV
                     EEYARQKRIRKNLDLICANDVSQPTQGFNSDNNALHLFWQDGDKVLPLERKELLGQLL
                     LDEIVTRYDEKNRR"
     gene            24827..25495
                     /gene="radC"
                     /locus_tag="RHX21_002257"
     CDS             24827..25495
                     /gene="radC"
                     /locus_tag="RHX21_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418095.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HDV1987428.1"
                     /translation="MKNNSQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTL
                     AKEMLENFGSLYGLLTSEYEQFSGVHGIGVAKFAQLKGIAELARRYYNVRMREESPLL
                     SPEMTREFLQSQLTGEEREIFMVIFLDSQHRVITHSRLFSGTLNHVEVHPREIIREAI
                     KINASALILAHNHPSGCAEPSKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAE
                     RGWI"
     gene            25712..25948
                     /gene="rpmB"
                     /locus_tag="RHX21_002258"
     CDS             25712..25948
                     /gene="rpmB"
                     /locus_tag="RHX21_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008457442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HDV1987429.1"
                     /translation="MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEK
                     RFVTLRVSAKGMRVIDKKGIDTVLAELRARGEKY"
     gene            25969..26136
                     /gene="rpmG"
                     /locus_tag="RHX21_002259"
     CDS             25969..26136
                     /gene="rpmG"
                     /locus_tag="RHX21_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010847629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDV1987430.1"
                     /translation="MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVR
                     QHVIYKEAKIK"
     gene            26234..27043
                     /gene="mutM"
                     /locus_tag="RHX21_002260"
     CDS             26234..27043
                     /gene="mutM"
                     /locus_tag="RHX21_002260"
                     /EC_number="3.2.2.23"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-formamidopyrimidine
                     glycosylase/DNA-(apurinic or apyrimidinic site) lyase"
                     /protein_id="HDV1987431.1"
                     /translation="MPELPEVETSRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRL
                     SDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVDLVMSNGKV
                     LRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMD
                     NKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLK
                     DFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQK"
     gene            complement(27082..27561)
                     /gene="coaD"
                     /locus_tag="RHX21_002261"
     CDS             complement(27082..27561)
                     /gene="coaD"
                     /locus_tag="RHX21_002261"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HDV1987432.1"
                     /translation="MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKP
                     MFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQL
                     AHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA"
     gene            complement(27569..28846)
                     /gene="waaA"
                     /locus_tag="RHX21_002262"
     CDS             complement(27569..28846)
                     /gene="waaA"
                     /locus_tag="RHX21_002262"
                     /EC_number="2.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A) 3-deoxy-D-manno-octulosonic acid
                     transferase"
                     /protein_id="HDV1987433.1"
                     /translation="MLELLYTALLYLIQPLIWIRLWVRGRKAPAYRKRWGERYGFYRH
                     PLKPGGIMLHSVSVGETLAAIPLVRALRHRYPDLPITVTTMTPTGSERVQSAFGKDVQ
                     HVYLPYDLPDALNRFLNKVDPKLVLIMETELWPNLIAALHKRKIPLVIANARLSARSA
                     AGYAKLGKFVRRLLRRITLIAAQNEEDGARFVALGAKNNQVTVTGSLKFDISVTPQLA
                     AKAVTLRRQWAPHRPVWIATSTHEGEESVVIAAHQALLQQFPNLLLILVPRHPERFPD
                     AINLVRQAGLSYITRSSGEVPSTSTQVVVGDTMGELMLLYGIADLAFVGGSLVERGGH
                     NPLEAAAHAIPVLMGPHTFNFKDICARLEQASGLITVTDATTLAKEVSSLLTDADYRS
                     FYGRHAVEVLYQNQGALQRLLQLLEPYLPPKTH"
     gene            29259..30317
                     /gene="rfaQ"
                     /locus_tag="RHX21_002263"
     CDS             29259..30317
                     /gene="rfaQ"
                     /locus_tag="RHX21_002263"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptosyltransferase
                     RfaQ"
                     /protein_id="HDV1987434.1"
                     /translation="MDKPFRRILLIKMRFHGDMLLTTPVISSLKKNYPDAKIDVLLYQ
                     DTIPILSENPEINALYGIKNKKAKASEKIANFFHLIKVLRANKYDLIVNLTDQWMVAI
                     LVRLLNARVKISQDYHHRQSAFWRKSFTHLVPLQGGNVVESNLSVLTPLGLDSLVKQT
                     TMSYPPASWKRMRRELDHAGVGQNYVVIQPTARQIFKCWDNAKFSAVIDALHARGYEV
                     VLTSGPDKDDLACVNEIAQGCQTPPVTALAGKVTFPELGALIDHAQLFIGVDSAPAHI
                     AAAVNTPLISLFGATDHIFWRPWSNNMIQFWAGDYREMPTRDQRDRNEMYLSVIPAAD
                     VIAAVDKLLPSSTTGTSL"
     gene            30314..31438
                     /locus_tag="RHX21_002264"
     CDS             30314..31438
                     /locus_tag="RHX21_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDV1987435.1"
                     /translation="MIVAFCLYKYFPFGGLQRDFMRIAQTVAARGHHVRVYTQSWEGE
                     CPDVFELIKVPVKSHTNHGRNAEYFAWVQKHLREHPVDKVVGFNKMPGLDVYYAADVC
                     YAEKVAQEKGFFYRLTSRYRHYAAFERATFEQGKPTQLLMLTDKQIADFQKHYQTEAE
                     RFHILPPGIYPDRKYSQQPANSREIFRKKNGITEQQYLLLQVGSDFTRKGVDRSIEAL
                     ASLPDSLRHNTLLYVVGQDKPRKFEALAEKRGVRSNVHFFSGRNDVSELMAAADLLLH
                     PAYQEAAGIVLLEAITAGLPVLTTAVCGYAHYIVDANCGEAIAEPFRQETLNEILRKA
                     LTQSSLRQAWAENARHYADTQDLYSLPEKAADIITGGLDG"
     gene            31431..32228
                     /gene="rfaP"
                     /locus_tag="RHX21_002265"
     CDS             31431..32228
                     /gene="rfaP"
                     /locus_tag="RHX21_002265"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312532.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptose(I) kinase RfaP"
                     /protein_id="HDV1987436.1"
                     /translation="MVELKEPFATLWRGKDPFEEVKTLQGEVFRELETRRTLRFEMAG
                     KSYFLKWHRGTTLKEIIKNLLSLRMPVLGADREWNAIHRLRDVGVDTMYGVAFGEKGM
                     NPLTRTSFIITEDLTPTISLEDYCADWATNPPDVRVKRMLIKRVATMVRDMHAAGINH
                     RDCYICHFLLHLPFSGKEEELKISVIDLHRAQLRTRVPRRWRDKDLIGLYFSSMNIGL
                     TQRDIWRFMKVYFAAPLKDILKLEQGLLSQAEAKATKIRERTIRKSL"
     gene            32244..>33175
                     /gene="waaO"
                     /locus_tag="RHX21_002266"
                     /gene_synonym="rfaI"
     CDS             32244..>33175
                     /gene="waaO"
                     /locus_tag="RHX21_002266"
                     /gene_synonym="rfaI"
                     /EC_number="2.4.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001540083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide
                     3-alpha-galactosyltransferase"
                     /protein_id="HDV1987437.1"
                     /translation="MSAHYFNPQEMINKTIIFDERPAASVASSFHVAYGIDKNFLFGC
                     GVSITSVLLHNNDVSFVFHVFIDDIPEADIQRLAQLAKSYRTCIQIHLVNCERLKALP
                     TTKNWSIAMYFRFVIADYFIDQQDKILYLDADIACQGNLKPLITMDLANNVAAVVTER
                     DANWWSLRGQSLQCNELEKGYFNSGVLLINTLAWAQESVSAKAMSMLADKAIVSRLTY
                     MDQDILNLILLGKVKFIDAKYNTQFSLNYELKKSFVCPINDETVLIHYVGPTKPWHYW
                     AGYPSAQPFIKAKEASPWKNEPLMRPVNSNYARY"
BASE COUNT         7878 a         8192 c         8853 g         8252 t
ORIGIN      
        1 gaacaaatta atcttgatgg cagtctgatt attggtgaag tttatagtca gtttttttcg
       61 ccagcggtta aagaaataga atagtcgtat aaaaaagggt gttctggggc gagtaaaaca
      121 acatcttcac cttaatggcg atacagttgg ctgagagtca gcaggggggc aaatcacctg
      181 caaataaaca cggcgcatac tggcgtgaat atcgcggatg cgttcgagga cagaagaacc
      241 gacaggcgga ttcttcagcc gctcatcgtc catcacaaaa ccttagacca ggtattcctg
      301 aagccgattg aatattgagc agtagaaaat atctggattg acagtattac aaggggttgg
      361 agaacgtcag gagaggcatt ttggcggaag atcacaggag tcgaacctgc ccgggaccgc
      421 tggcggcccc aactggattt gaagtccagc cgcctcaccg gagacgacga tcttccgcgc
      481 ctcgattgct acatggaggc ggggcgcatt atagctactt ccttgagttt ctacatcccc
      541 cagatcagtt ttttccgcct aatacacgca gcgtattatc acgaaagcat tatagttcat
      601 ataaaaccca tattttacaa tgatatatga gcggaattaa cgctaccacg atcacataaa
      661 acaagaatca taaattaata accagatatc ggaatattcg ctctcacagg gatggtttac
      721 aaaatgcgtt atcggtctca gcacccctat agcatcaagg aaaagcagat gaagagtgaa
      781 gtgttgtccg ttaaagagaa aattggttat ggcatgggag acgccgccag ccacattatt
      841 ttcgataacg taatgttata tatgatgttc ttttataccg atatttttgg cattcctgcc
      901 ggatttgtcg gaaccatgtt tttggtcgct cgtgcactgg atgcgatttc cgatccttgc
      961 atggggttgt tggccgatcg aacgcgctct cgctggggta aatttcgtcc gtgggtactg
     1021 tttggcgcac tgccattcgg gatcgtctgt gtactggcct atagcacgcc agatctcagt
     1081 atgaacggca aaatgatcta tgcagcaatt acttacaccc tacttacctt actttatacc
     1141 gtcgtcaata tcccttactg cgcattgggt ggtgtaatca ccaatgaccc gactcagcgt
     1201 atctcgctgc aatcctggcg ttttgtgctg gcgaccgcgg gaggcatgct ttctactgtt
     1261 ctgatgatgc cactggttaa tttaattggc ggtgataata aaccactcgg tttccagggc
     1321 ggtatcgcgg tcctttccgt ggtggcattc atgatgctgg cattttgttt cttcaccact
     1381 aaagaacgcg ttgaagcacc acctacaaca acgtctatgc gggaagattt acgtgatatc
     1441 tggcaaaacg accagtggcg gattgtcggt ttactaacca ttttcaatat cctggcggtg
     1501 tgcgtacgcg gtggggcgat gatgtattac gtcacatgga ttttgggcac gccggaagtg
     1561 tttgtcgctt ttctcaccac ttattgcgtg ggtaacctga ttggttccgc actggcaaaa
     1621 cctctgaccg actggaaatg taaagtcact atcttctggt ggacgaacgc cctgctggca
     1681 gtgattagcc tcgcgatgtt ctttgttccc atgcaggcca gcatcactat gtttgtcttc
     1741 atcttcgtga ttggtgtgtt gcatcaactg gtgacaccta tccagtgggt aatgatgtcc
     1801 gataccgtcg actacggcga gtggtgcaat ggtaaacgcc tgaccgggat cagttttgct
     1861 ggcacgctgt ttgtgctcaa actggggttg gccttcggcg gcgctcttat cggctggatg
     1921 ctggcttatg gcggatatga tgcggcagaa aaagcgcaga acagcgccac gattagcatc
     1981 attattgcgc tattcacgat tgttccggcg atctgttatt tgctgagcgc gattatcgct
     2041 aaacgctact actcactcac gacgcacaat ctgaaaaccg ttatggaaca gctggctcag
     2101 ggtaaacgcc gttgccagca acaattcacc tctcaagaag tgcagaacta aggaacggca
     2161 atgaaaatta gcgatggaaa ctggttgatt caacctggcc tcaatttgat tcacccgctt
     2221 caggtgttcg aggttgaaca gcaggataat gaaatggtgg tctatgctgc cccccgtgat
     2281 gtgcgtgaac gtacctggca gcttgatact cctttattta cgttgcgctt tttctcccca
     2341 caggaaggta ttgtcggtgt gcggattgag cattttcagg gggcgctgaa taacggtcct
     2401 cattatccgc tcaatatttt gcaggacgtg aaggtcacaa tcgaaaacac agaacgttat
     2461 gctgagttta aaagtggcaa cttaagcgcg cgtgtcagca aaggtgagtt ctggtcactg
     2521 gattttctgc gcaacggcga acgtattacc ggtagtcagg tgaaaaataa tggctacgtg
     2581 caggacacga ataatcaacg caattatatg tttgagcggc ttgatcttgg cgttggcgaa
     2641 acagtttacg gtctgggaga gcgctttact gccctggtgc gcaatggcca gacggtagag
     2701 acctggaacc gggacggcgg cacaagtact gaacaggcgt ataaaaatat cccgttctac
     2761 atgactaacc gtggttatgg ggtactggtc aatcatcccc agtgtgtctc ttttgaagtg
     2821 ggatcggaga aagtctccaa agtgcagttc agcgttgaga gtgaatatct cgaatacttt
     2881 gttatcgacg gcccgacgcc gaaagcggta cttgatcgtt atacccgctt tactggtcgt
     2941 ccggcgctgc cgcccgcgtg gtccttcggc ctgtggctaa ccacttcatt taccaccaac
     3001 tacgacgaag cgacggtaaa cagctttatc gatggtatgg cggaacgcaa tctgccgctg
     3061 catgttttcc actttgactg tttctggatg aaagccttcc agtggtgcga ttttgagtgg
     3121 gacccgctga ctttccctga cccggaaggg atgatccgcc gcctgaaagc gaaaggactg
     3181 aaaatctgcg tctggattaa cccctatatc ggtcaaaaat cccccgtctt taaagagtta
     3241 caagagaaag gctatttact caaacgcccg gacggttcgc tatggcagtg ggataaatgg
     3301 cagccaggtc tggcgattta tgactttacc aatccggatg cctgcaaatg gtacgccgac
     3361 aaactgaaag gtctggtcgc gatgggcgtt gattgcttta agaccgactt tggcgaacgt
     3421 atcccaactg atgttcagtg gtttgacggt tccgatccgc agaaaatgca taaccattat
     3481 gcgtacatct acaacgaact ggtgtggaac gtgctcaagg acaccgttgg tgaggaagaa
     3541 gctgtcttgt ttgcccgctc ggcctccgtc ggtgcgcaga aattcccggt acactggggt
     3601 ggcgattgtt acgctaacta cgaatcaatg gcggaaagcc tgcgcggtgg tttgtctatt
     3661 ggcctttcag gttttggctt ctggagccac gatatcggcg gctttgaaaa taccgctccg
     3721 gcgcacgttt acaaacgctg gtgcgcgttt ggtttgctct ccagccatag ccgtttacac
     3781 ggtagcaaat cttatcgtgt gccgtgggac tacgatgatg agtcctgtga tgtggtgcgc
     3841 ttcttcacgc aactgaaatg ccgcatgatg ccgtatctgt atcgtgaagc tgcgcgtgcg
     3901 aacgcgcggg gtacgccgat gatgcgggcc atgatgatgg agttcccgga cgatccggct
     3961 tgtgattacc ttgaccgtca atacatgtta ggcgacaacg tgatggttgc gccggtgttc
     4021 actgaagcgg gcgatgtgca gttctacctg ccggaaggtc gctggacaca cctgtggcac
     4081 aacgatgagc tcgacggtag tcgctggcat aaacagcagc acagcttcct gagtctgccc
     4141 atttatgtgc gtgataacac cctactggcg ctgggcaaca acgatcaacg tcccgattac
     4201 gtgtggcacg aaggcacggc attccacctc tttaatctgc aagacgggca tgaagccgtc
     4261 tgtgaagtgc ccgctactga cggatcggtg atctttactt taaaagcagc acgtactggc
     4321 aacacgatta ctgtgactgg tgcgggcgag gcgaagaact ggacgctgtg cctgcgcaat
     4381 gttgtgaaag taaatggtct gcaagacggt tcgcaggctg aaagtgagca ggggctggtg
     4441 gtgaagcctc aagggaatgc gctgacaatt acgttgtaat ctattgatgg aatgccgggt
     4501 acgtctgagt cgtacccggc gagattgatg tttaccgcac cggctccgtc gatgtaactt
     4561 caccgctgga aacgatgcca gcattcatgg tttgagtcac ttgctgcttt gcggcgttca
     4621 cggcatgcaa ttgcccgcta accgtaggtt tcaacgggac attggcctga atatcgccac
     4681 tggcggtaag ctgaatattg ccgtcgccag tcaacggtaa tttaggccat ccccactgtt
     4741 gcaaaatatt caccggcaca ccgcgtccat tcaggctgat atgtgtctga cgttgtggcg
     4801 tttgtgaaac actggcggtg gcttccagaa tgcctttttc agtaaatgca ctcagttcgc
     4861 tgatattcac cgtgctgctg ttggcggtca gcgccagcga cgggcgacga acatcaacac
     4921 gattgaatgt cgcggcggcg gcattcagat tcgccgagcc actccagacg ccccatttat
     4981 gatcggtaac cagcgtcagg ttggcaccgt aaccatcgag cgcggtgagc tgccacggga
     5041 agtcagggtc gatatcaatg atcagattgc ggctggcgct aaatctcttc agttgcaggc
     5101 tgtttaacca accgggtgtc gtttctatcc acaactgttg ccagtttttc ggcaaggtat
     5161 attccagccc ggcaattgcc acatcatcaa ggatcaacgt tttcccgtca cgcagccagt
     5221 tccctgacgt tctgaccata cccccttccc agcggctggt gaactggcgc agcgctacgc
     5281 cctgcgggga aaattccgcg tttataatcg ggtcaaataa atgcagcgaa ccataaatga
     5341 actcgctagc gttcatcgac agtttgcctt cctgtgtctg ccagtcatct ttactgaagg
     5401 tcatgttgcg caagctgaga tcgaggtcgg tcaccgccca gtccggacct tgcaaacgag
     5461 catcgatcac ttccaggcga ccaatctgca acgacgggac agagcgtaat ggcgcaaaga
     5521 agtcggttag cgatttttcg ctttgtagac gtatatccgc catgcgcagg ttttccactt
     5581 gccagctgcc gtcggcgtta cgctgcgcgt ttccggttaa tgtcccgcgg gcgatgtcgg
     5641 cacccaggtt agtcagcgta acgcgatcgt tatcaatact gccttcaatc agtacattgg
     5701 tggcaggaac atcattgagc gaaagcgatc cggcactaaa ctgaatctgc gccttcgtac
     5761 ccagcacttt accggctttt ggtgaccacg gaactacgcc gccatttacc cgctgcgcgc
     5821 tcagtttcca ttcgctattc gggctattaa acgccatatc acgcagttgc agacgatcgg
     5881 ctttgaacgg tagcggcgcg gtctggtcgg tgagattcag cgtcccgttt tccagcagga
     5941 tggtatcgac atggcgtggt tcggtcagtt gccgactgct tagcgcaatg tcgacacttt
     6001 ttgccaccag ggtcgcgggc tggccatcac ggccaaacgt gacgttctcc agcacgatat
     6061 gagatggcgc ggaaaaacgg tgatccatcg ccccgaaggc cagatgatag tcgctattct
     6121 cggaaaccca tgcgctgata tgttctgctc cccagcgggt ttgcagaaga aaatagaggc
     6181 cagcgatcac cactaacaga gcgatgagaa tgtagagaag cagcttccca ataaatttca
     6241 tggtcttcca tcccgtgaaa tgcacataag ggagttatgc acgatttacg cgcaatcctc
     6301 aaggcgggaa tggtgaaaga ggtgagactg cggcggtaat tatcttaccg ccgccagtga
     6361 attactgttt ttctggtggg aaaatcagat tcagcacgat ggcagtaata ccgcccgcgg
     6421 cgatcccgga ggagagcagg tttttcagcc attcaggggc aaactgcaaa atcagcggct
     6481 gctgagacac gcccagacca accgccagcg acagcgcgat aatcagaatc gcccgacggt
     6541 tcagcggctc acgagaaacg atacgcacac cggaggcggc gatggtgcca aacattacaa
     6601 gcgttgcgcc gcccagaacc ggttctggaa tgtgttgtac aaaaccgctc actgccggga
     6661 acagacccag cacgatcaac atcagcgcga cgacaaaacc gacatagcgg ctggcaacac
     6721 cagtcaactg gatcactccg ttgttttgcc cgaagcagga gttcgggaag gtgttaaaca
     6781 ccgccgaaac aaacgagttc aggccgtttg ccagcacgcc acctttcagg cgtttcatgt
     6841 acagcggacc ggacactggc tgttcggaaa cgtcagaggt cgccgtgata tcgccaatgg
     6901 tttccagcga agtgatcata aagaccagca tcagcggcag cagcagactc cattcaatgc
     6961 caagaccgta atagagcggc gttggcacca taatcagttc ttgcgtcatc ggttcgttgc
     7021 tttctggcaa catgcccata aaccacgcca gcgcatatcc ggccgccatc gcaatcacca
     7081 gtgaggccac gcgtaagtaa gggttacgtt gacggttaag caggataatt aaggctaaga
     7141 ccacgcctgc cagcagcaga tttttcggtg cgccgaaggt gttatcgctc atggctgcgt
     7201 aaccgccgcc aatggacgtt aacccaacct gaattagcga caggccgata atcatcacca
     7261 caacgccaga aaccagcggc gtaataatgc ggcgcgccag atgcagaacg cgggagatca
     7321 ccatctcggt gcaacttgcc agcatcaacg tgccgaacaa agccgccatc atggtaggaa
     7381 catcagcacc accggttttc agcgcggtac cgcccataat cagcggggca acaaagttga
     7441 agctggtgcc ctgaatagac aacagcccgg agccaaccgg accccaggcc ttaatttgaa
     7501 taatcgatgc cacaccggag gcaaacagcg acatactaat aatgtgttgc gtgtcttgtg
     7561 ccggtaaacc cagcgcctgg cagattaata gcgctggcgt gatcaccgca acgaacatcg
     7621 ccagcagatg ctgacaggcg gcaaacaggg tttgaggaag cggcggacga tcttcaagac
     7681 ggtaaatcag ttcgctgttt tgagtctgcg caaccggttg cgcattttct gactcgaggg
     7741 tggaaacaga catcgaaaac aatcccgtgg tagcaaagcg ggcattttag ctgaccgaaa
     7801 gagaaaagca aacgtttgcc acatcctcat ctaaatattt aaatgagata aatgcacttt
     7861 tttatataac ttttggtatt tttctgctta aaatccatgc catttgttca ttaacagctg
     7921 agaatttgac ccaggaaagc ataactcgat acccgtcata gttcatgaag ttgccactgc
     7981 gcgatgaagt atgacgagta tgaaagagtg atgcggatac aaaggagtaa ctatgtttca
     8041 tctcgatact ttagcaacgc ttgttgccgc aacgctgacg ttgctgctcg ggcgtaagtt
     8101 ggtccattcc gtctcctttt tgaagaaata caccataccg gaacctgttg cgggtggttt
     8161 gttggtggcg ctggcgctac tagtactgaa aaaaagcatg ggctgggaag tcaactttga
     8221 tatgtccctg cgcgatccgt taatgctggc tttcttcgcc accattggcc tgaacgccaa
     8281 cattgccagt ttgcgtgccg gtgggcgtgt ggttggcatc ttcttgattg tggttgttgg
     8341 tctgttggtg atgcaaaatg ccattggcat tggtatggct agcctgttag ggcttgatcc
     8401 gctgatgggg ctgttggccg gttctattac gctttccggc ggtcacggta cgggcgctgc
     8461 gtggagtaaa ttgttcattg aacgttatgg cttcaccaat gcgacggaag tggcgatggc
     8521 ctgtgcaacg ttcggtctgg tgctgggcgg cttgattggc ggtccggtgg cgcgctatct
     8581 ggtgaaacac tccaccacgc cgaacggtat tccggatgac caggaagtcc cgacggcgtt
     8641 tgaaaagccg gatgtgggcc gcatgatcac ctcgctggtg ctgattgaaa ctatcgcgct
     8701 gattgctatc tgcctgacgg tggggaaaat tgttgcgcaa cttttggctg gcactgcttt
     8761 tgaactgccg accttcgtct gtgtactgtt tgttggcgtg attctgagca acggtctgtc
     8821 aatgatgggc ttttaccgcg tctttgagcg tgcggtatcc gtgctgggta acgtaagcct
     8881 gtcgttgttc ctggcgatgg cgctgatggg gctgaaactg tgggagctgg cttcgctggc
     8941 gctgccgatg ctggcgattc tggtggtaca gaccatcttc atggcgttgt atgccatctt
     9001 cgttacctgg cgcatgatgg gcaaaaacta cgatgcggca gtgctggctg cgggtcactg
     9061 tggttttggc ctcggtgcaa cgccaacggc aatcgccaac atgcaggcga tcactgaacg
     9121 ctttggcccg tcgcacatgg cgtttttggt ggtgccgatg gtcggtgcgt tctttatcga
     9181 tatcgtcaat gcgctggtga ttaagctgta tttaatgttg ccgatttttg ccggttaaaa
     9241 atgaaaaagc gtcggaagga accggaaacg ctacgtgaac actgtcgcca tatttttggt
     9301 gatgagccgc cagtgctctg tgtatgggaa acggaatttg attacgcaga tgccgaactc
     9361 aaggcgctgg cggctaaaga gtggcagcag atcagcgtat gggatttgag tgcttactat
     9421 gtactcaatc tcgtttataa cgaaccgatg caaatagagt tgtttcgcta tctgtttccg
     9481 ctctgcctgg cgcaatggca tgaaaccgtt ttagctggcg gttatggtga tcacttcgaa
     9541 gaatccttaa tgaaggcatt gtgtcggccc tatctctggc aggagatgat gaatgcttcc
     9601 caacgccagc aggtacggca atttttactg gacaccgcgt tgcagcgtat ggataacgag
     9661 cgtggtttca ataacgttct ttgctggctg gcggtgttca atactctggg tggggccgcg
     9721 ccgttaattc attctctctg gtcgcgctgg tgggcgctgg atacgccagg aaaagcggtg
     9781 tgtgctattc agtatgccgc gcatctaatt tatcccatag aagccaatcc gttatggtcg
     9841 caagaatgga taggctgggg gcatccatta ggccataaag atggctggtc ctctgataat
     9901 cgcgcttttc ttcgccaaat gttaacacct gaaatgattg tggctggcgt acaggcagcg
     9961 gctgaaattc tgcgtggtga accggaaggc gcaatggcgg cgcgaattgc acaggatgcg
    10021 tatgaggcaa tggatatcct cactatccag attgaagatt tactgcgtga cttgtcttgt
    10081 gatgagtctg gtcatgcgtt ggagtaacgt tccgtctccg gcatccagcg ttctatcagg
    10141 gcttttgctt gttgtgggta acgttcgtga atatgtcgcg ccaggcgctg aacttccggg
    10201 atcatcgcct gatcgcgcag taaatccgcc actttaaact cagcattacc cgtctgacgc
    10261 gtacctaaca gttcacccgg tccgcgaatc tctaagtctt tctgtgcaat cacaaaaccg
    10321 tcgttgctgt cgcgcagcac ttgcagccga atttgcgcgg ttttggagag cggcgttttg
    10381 tagagcagca cgcagtgaga agccaccgca ccacgaccta cacgcccgcg aagctggtgt
    10441 aactgcgcca gacccagacg ctccgggttt tcgataatca tcagactggc gttaggcaca
    10501 tcaacgccga cttcaataac ggttgtggca accagcaggt gtagctcacc ttgtttaaac
    10561 gacgccatca ccgcctgttt ctcgacaggt ttcatccgcc cgtgtaccag gccaacgttc
    10621 aactctggta gcgccagttt caactcttcc caggtagctt ccgccgcctg cgcttccagc
    10681 aattccgact cttcaatcaa cgtacaaacc cagtatgcct gacgaccttc agttatgcag
    10741 gcgtggcgca cgcggtcaat gatgtcggta cggcgggtat caggaatagc gaccgtagtc
    10801 actggcgtgc ggcctggcgg cagctcatct atcaccgagg tatcgagatc ggcatacgca
    10861 gtcattgcca gcgtgcgggg gatcggcgtg gcggtcatga tcaactgatg cggatggaag
    10921 ccctgctgct ggcctttctc ccacaatgcc agacgctgat gcacgccaaa acgatgctgt
    10981 tcgtcgataa tcaccagcgc caggccgtta aactgcacct gttcctggaa gatggcgtgt
    11041 gtaccgacaa tcatctgcac ctgaccgctg gcgatggctt cctgctgtgc cagccgtgct
    11101 ttacctttct gcttaccggc gagccagccc acttcgatac cgagcggtgc aaaccagttg
    11161 cggaagttat tggcgtgctg ctcggcgagt aattcggttg gtgccatcaa tgctacctgt
    11221 ttgccgtggg caatcgcacg caacgcggcg agggcggcga ccagcgtttt accggaacct
    11281 acatcgccct gcaccagacg catcatcggc acatccagcg ccatatcgcg ctcgatctcc
    11341 gccactacgc gtgcctgtgc gcccgttggc ttgaacggta aggcggcgag gagtttattt
    11401 ttcagcgtgt cattggcgct cagcggctgg gcatgaaaac gctgtgctcc ggcacgtaag
    11461 gctaacatgc tgaggttgtg cgccagcagt tcttccagaa tcagacgacg ttgcgccgga
    11521 tgctgcccgg tttccagatc gctaagctgt agcgtcggtg gcgggcggtg caaagtgcgc
    11581 aacgcttccg gtagcgtcat cattccttgt gacagttccg gcggcaggag ttcttcaatg
    11641 gcgcaggtgt cgagcagatc cagcgcctgg tcggttaatt tacgcagcgt ggcctgcttt
    11701 acgccttccg ttgttggata aaccggcgtg agcgtttcct gtaattctgg cgtgctgaga
    11761 tcgccctgca cgcggtattc cgggtggatc atctccgcac catatttacc gcgctttgct
    11821 tcgccataag ccagtacacg gcggcccgtc gccaggctat ttttcattgc cgcgctgaaa
    11881 ttgaaaaagc gcatggtgag gatgccggaa ccgtcgctga tctggcaggt catcatccgc
    11941 cgaccgccga aggagatatt gcagttcagc acttcgcctt ccaccgtggc ataaacgccc
    12001 ggcagtagtt ctccgatggg gtagagatgg gtgcgatctt cgtagcgcag gggaaggtgt
    12061 aagagtagat cctgcacggt atgcaggttg attttcgcca gtttgttact aagtgctgcg
    12121 ccaacgcccg ttagggaact gagtgggaca gcatctaaca ggcgaccttt catggcactt
    12181 accctgcagc ctgcatagta gcccaccagt cggcatcagc ttcgatctcg ccttgctgat
    12241 tgacgtgggg ataaggcagg cctttgcgtt ttgcgacttt cgccagcacc ggatagccgc
    12301 cttcaaacaa caggcgttgt tgctctgctt ccggcaacat gctgttttca cgcaggtaca
    12361 tgcctgcatt ttgccgctga cgctgggctt cgtaaagaat gagggctgag gcaacggaaa
    12421 cattcagcga ctgcaccatg ccgatcatcg gaatgatgat gtcctgatcc gccagggcca
    12481 atgcttcctg cgtgatgccc gttttctcct gtcccatcaa aatgcaggtc gggcgagtgt
    12541 aatcaatttc gcggaaatcg acagcgttat cagaaagatg ggttgccaga atctgcattc
    12601 cctggccttt gagatgagcg acggcatcgc caatggtgcg gtgtgttttc acctgtaccc
    12661 agctgttact acccgccgct gccgaagcca tggtgcgcat gcggctacca ggccagacgg
    12721 cgtgaacttc atgtacgcca acggcatctg cggtacgaat aatcgcagaa acgttatgag
    12781 gtttgtggac ctgctccatg cagacggtca gatcaggctg ccgcctggcg agcatttcgc
    12841 agatgcgtgc ataacgtgtt gggttcataa aacattaatt tcggtttcgg gtgactttaa
    12901 tcacgtctgg catcacgcgg attttgcgca tgatattcgc cagatgcaca cggtcacgag
    12961 cggtcagacg aataaaggcg ctgtagacgc gaccatcttt ctcttccgta ttcaaacttt
    13021 gaatattcga ggtcgtggtg ttaattgccg ccgtcaggtt tgccagcgca ccctgatgat
    13081 tgaacatctc caccttgatt tcggtgatga actcctgcgc cgtctcttta tcccattcca
    13141 cagccataaa cttctctggc tctttctggt agccacggat gttacggcag gattcatggt
    13201 ggatcaccag acctttaccg gggctgacgt gggcgataat cgggtcgcca ggaatggggc
    13261 ggcagcattt cgcaaaggtg atcagcacgc catcagcgcc tttgatcggc agatgcccgt
    13321 ggctttgagt cgccggtgga atggaggcgt ccccatgttg tagatttttc gcgaccacca
    13381 cgctcattgc gttaccaagg ccgatttctg ccagcagatc gtcaagcgtt gccagcttca
    13441 tgcgatccag ctcgcgctga atattttcct gcgggatttc attcagctta cggctaccac
    13501 ccaaagcatg gttgagcaga cgacggccca ggcttacaga atcatcacgc ttgaggtttt
    13561 tcagcaactg acgaattttg gcgcgcgctt ttgagctaac gacaaagttc agccacgcgg
    13621 cattcgggcg agcgcccggt gcggtaatga tttcaacggt ttgaccgctg gtaagcggct
    13681 gcgacagcgg gtaaggctgg cggtcaacgc gtgcgcccac gcaggcatga ccgatatcgg
    13741 tatgcactgc ataagcgaag tcgacgggcg ttgcaccggc aggcagctcg acaattcgcc
    13801 cttccggtgt gaaaacgtaa atctcatccg ggaagagatc ggatttaacg ctctcgataa
    13861 attcaaacga actaccggcg ctctgttgca gctccagcag gctttgcatc cagcgctggg
    13921 cgcggatttg tgcggtagta ctggtttcgc cgtgctcttt ataagcccag tgcgcggcaa
    13981 cacccatctc cgccatctga tccatatctt cggtacggat ctggacctca accggcacgc
    14041 cgtgcgggcc aatcatcgag gtgtgcaacg actgatagcc gttcgcttta ggaatggcga
    14101 tatagtcttt cacgcgaccc ggacgcggct tgtacaggct atgcatttgc ccgagcacgc
    14161 gataacaggt gtcagaatca ttgacgatca cgcggaaagc gtagatgtcc atgattgagt
    14221 gaaaacgctg ctctttgagc accattttgc agtaaatcga ataaagatgc ttttcgcgac
    14281 cactgacgcg gcacggtatt cccgcttcct gcaaacgccc ttcgatttca gagaggattt
    14341 tttggatcat ctctttacgg ttgccgcgcg cggctttcac cacttcttta attacgcggt
    14401 aacgattggg atacagcgcc tcaaaaccca gctcttcgag ttcggtttta atgtggtgga
    14461 tacctaaacg gtgcgccaac gggctataaa tttcgagagt ttcacgggcg atgcggcgac
    14521 gtttgtccgg gcgaagtgag cccagcgtgc gcatgttgtg ggtacggtcg gcaagtttga
    14581 tgagaatgac gcggatatcc tgcaccatcg ccataatcat cttgcgaaag ttttcggcct
    14641 gcgcctcttt cttatcgcgg aacttgagct tatcaagttt cgacaccccc tctaccagct
    14701 cggcgacgct tttaccaaaa agctgttcca tgtcctggta ggtggcggga gtatcttcaa
    14761 tcacgtcatg cagcagcgcc gccatcagcg tttcatagtc gagtttcatc tcggccagaa
    14821 tgcaggcaac cgctaccggg tgcgtgatat agggttcacc gcttgaacgt gtttgcccct
    14881 cgtgagcatc acgtgcaacg agatacgcct gccgcagacg cttgatttgg tcttccggca
    14941 ggtaggtttg aatcagttga ttcaggcttt caaacagata caagggcgac ccgctttgtg
    15001 attaacgacg accttcagca atagcggtaa cggcttgtaa ttcagcggct tcctgctctt
    15061 gctgttcctg gcgttcgcga acgtcgagga tctggttgtt gatcagacct tcttcgattt
    15121 cgcgcagcgc gattacagtg gttttatcgt tttcttccgg taccagcgga tcctttccgc
    15181 ctacctgcat ctgacgagcg cgacgcgcgg cgaccagtac caggtcaaaa cggttaccaa
    15241 ttttctctac agcgtcctga acagttacgc gtgccatact taaaaagctc cacaggtgaa
    15301 gaaatgactg ggcatgatac tgaaatcagg ttcagtctgc caacaatttg ctgattaaag
    15361 cgtcatgacg ctgcttttgg cggctcatgc gcagacgttc ggcgcgaata atggtcttca
    15421 aatcggtcaa cgcggtatcg aagtcatcat tcacaatcag ataatcatat tcggcgtaat
    15481 ggctcatttc tgcaacagct tgcgccatac gctttgcaat gacctcttcg ctgtcctgac
    15541 cgcgaccgcg tagacggcgg tccagttcaa ttttggacgg cggtaaaata aagatactcc
    15601 gcgcgtgcgg cattttctgg cgaatttgct gcgcgccctg ccagtcgata tcgagaaaaa
    15661 catcgacacc ggtcgccagt acttgctcaa tggcctcacg cgaagtgcca tagtaattac
    15721 caaaaacttc tgcgtgttcg aggaacgcat ctctgctaat catttcttta aattcatcat
    15781 gattaacaaa gaaataatgt tcaccgtgga cttcaccagg acgcggttgg cgtgtggtgt
    15841 gtgaaacaga aacctgggtg tcatacaacg gttgggtttt taataaagcc tgaatcaggc
    15901 tggatttacc cgcgccactg ggggcagaaa caatataaag cgtgccttga gccatgagta
    15961 tctttcgtat gtgattagcg aaataaagcc tacatacgag cttattatac acggcgcggc
    16021 catgtgacgt agcccttgct cacacttttt gcgcaaagtt gttgcgtttt gcgtagctgc
    16081 ttccgcattt gcctgtcatt cactgcaata aagacgattt tcaggaagcg tcctcgcaga
    16141 ctccgttttt gccactcggc tttgctttca tcacgttgta tatctgcctg actacctaca
    16201 gcggaggtga tgatgaaagt atggatggcg atattaataa gtatcttgtg ctggcaatca
    16261 tctgtgtggg cggtctgtcc ggcctggtcg ccagccagag cacaggaaga aatttcccgc
    16321 ctgcaacagc aaataaaaca gtgggacgat gactactgga aggaaggaaa aagtgaggtg
    16381 gaagacggtg tttacgatca gttaagcgcc cgtcttacgc agtggcaacg ctgctttggg
    16441 agcgagcccc gcgacgtgat gatgccgcct ttaaatggtg cggttatgca tccggttgcc
    16501 catacgggtg tacgcaaaat ggtggataaa aacgcattaa gtctgtggat gcgagaacgt
    16561 agcgatcttt gggtgcagcc aaaagttgat ggcgttgcgg taaccctggt ttatcgggac
    16621 gggaaactga acaaagcaat cagtcgcggt aatggcctga aaggcgagga ctggacgcag
    16681 aaagttagct taatttccgc tgtgccgcaa accgttagcg ggcctttagc caacagtacg
    16741 cttcaggggg aaatatttct ccagcgcgag gggcatatcc aacaacaaat ggggggaata
    16801 aatgcccgcg caaaagttgc tggcctgatg atgcgccagg acgatagcga cacgctgaat
    16861 tctctgggcg tttttgtctg ggcatggccg gatggaccgc agttaatgac cgatcgttta
    16921 aaggagctgg ctaccgcagg ttttactcta acgcagaggt atacccgtgc ggttaaaaat
    16981 gctgatgagg ttgcgcgcgt acgcaatgag tggtggaaag cgaaattacc cttcgtcacc
    17041 gatggcgtgg ttgtgcgagg ggcgaaagaa cccgaatccc gccattggct accaggccag
    17101 gcagaatggc tggtggcctg gaaatatcaa cctgtagctc aggttgccga agtgaaggcg
    17161 attcagtttg cggtgggtaa gagcggtaaa atatcggtgg ttgcgtcact cgcacctgtc
    17221 atgctggatg ataaaaaagt ccagcgggtg aatattggtt ccgtcaggcg ctggcaggag
    17281 tgggatattg cgcctggtga tcagatcctc gtcagccttg ccggtcaggg tattcctcgc
    17341 attgatgatg tggtctggcg cggtgcagaa cgtacaaaac cgacaccacc agaaaaccgc
    17401 tttaactcgt tgacctgcta ctttgcttct gatgtttgtc aggaacagtt catttcacgc
    17461 ttagtctggc tggggtcaaa acaggttctg gggctggatg gtattggtga ggccggctgg
    17521 cgcgcgctgc atcagactca tcgctttgag catatctttt cctggctttt attaacgcca
    17581 gagcaattac agaacacgcc ggggatcgcg aaaagtaaaa gtgcgcagct atggcatcgg
    17641 tttaatctgg ctcgtaagca gccttttact cgctgggtga tggcaatggg aataccgcta
    17701 acccgggcgg cgcttaatgc cagtgatgaa cggtcctggt cgcaactttt atttagcacg
    17761 gagcagttct ggcagcagct gccggggact ggatcggggc gcgccagaca ggttattgaa
    17821 tggaaggaaa atgcgcaaat caagaagctg ggcagttggc tggctgccca gcagatcaca
    17881 ggttttgaac cttagtgtcc ttcgtggctg tagtaaaaga ccggtaatcc cagcttaagg
    17941 cgtagcgcca gtaagcgggc aaaaaagccg aataccaggg tggagataat taccacatca
    18001 tggttagaaa catagtgttg cagcgcgatg tacagcacgg cggaggcaaa tgagacaccg
    18061 gcatacaact ctttctggaa taccagtggg atacgtttac agaacatatc gcgcaaaacg
    18121 ccgccaaaca cgccggtggt taccgccgcg acaacggcaa taattgggcc gtgccccata
    18181 tccagtgcaa cctgtgcgcc gatgatagaa aagaccacca gtccaagcgc atcgagcacc
    18241 agaaacactt tgcgcaggta aggcattaca ggagcaacga tagtggtgag tactgcggcg
    18301 gtagcgacga taatcacata ttccgggtgt ttgacccagc cgagcggata gtggcccagc
    18361 agaatatcgc gcactgaccc tccgccaatt gcggtggcgg tcgcaataat aattacgcca
    18421 aatgtatcca tgcggcgtcg cccggccgcc agagcccccg tcatggcttc ggcagtaatg
    18481 ccaaccaaat acaaaatgtg taacagcatg gttctctccc taaaaatctg tctggcaggg
    18541 tagcgatttg tgcgtattgt cacgattgag attttttaag gtgagaggaa attgataact
    18601 tgtagttatg tgaaatcgct attttctgta gcgtagatgc attcttctga cttcttgtct
    18661 gagaaaatgc ataagaaaaa ataggttaaa attgaggggt ggaaaagaaa ggtgcaatgt
    18721 ttagccattg tgttcaccgc acctggactt tggcttacgc atcgggtatc tcaatcaaca
    18781 aaaagagttt ttagtttctg ctatttcttc tctgtaattt ttacactgtt ttccaactgc
    18841 ttgatgctga cctgcggggt cggcaactcc tcaggcatgg ttccgccaag ttcctgaatg
    18901 gtttgcctca ccttgctacc cacgtcaaag tgtgtggtat tagcttgctg ttttgaattc
    18961 acgccatccc gcttgagttt ttcttctgtt tgggtagctc gaaagagatt agccgccagt
    19021 tctgttgaac ccatatgatc caggatcttc tgactctttt tcagcccctt ccgctgatgg
    19081 atggctttct gatctaatcc accatacagc ccccggtaac catgattctg aaatatggcg
    19141 aaatcgatag ctgtcgctac cccagcttgc tgcgctgcct caaccaattg tttgttatgt
    19201 tctttcaatt catttctcag aaaaagacgc ttttcgtctt cacgaagttg cctgaaagct
    19261 tcatcgtcag ccagctcctg ccgtcgggtc tggatagcaa aataagtttg ccctgccgca
    19321 ataaccggtt tcgcagggtc gccgttttgt actaccaggt aacaggcata gcgggagaga
    19381 tgaacatctt caagttctcg ttgagcccct gaacctaata caaccatttt ggtggtttca
    19441 acgaaatggt cagatgcagc ttgattgctg gcttcgcacg cttgagtcgc gcgggccagt
    19501 accttttgaa aattgcgcca gtcccgataa tccagtaacg gtgccaattc tctagctgac
    19561 caaaattctt gcccttcagt gccataatgc cgtatttctt caaaaggttg atgatgttcg
    19621 ttcattgccc actccatgtg atatcgattg caaagaaagt aaatctgtaa ctgtatttat
    19681 atacagttgt gagtatctca cgttctcagt gtgctgggca aaaaaacatc gcaaaatctg
    19741 gagcaggcac gcaaaacaga attgaagttg cggggaagaa aaatgccgct ctgtttgagt
    19801 gggcggcatt tgtgaaggct gaaaagtaag aattggcgtt acgagttatt caatgttctg
    19861 aatctgctcg cgcatctgct caatcaacac tttcagctca atcgcggagt ttgtcacttc
    19921 ggcattgata gacttcgacg caagagtgtt cgactcgcgg ttgaattcct gcatcataaa
    19981 gtccagacga cgaccaacgg cttctttttt cttcagaatg ttgtaggtct ctttgacatg
    20041 cgcttccagg cggtccagtt cttcggcaac gtcaattcgt tgtgccagca gaaccagctc
    20101 ctgctccaga cggttgtttt ccaactgaac ctgagcatct tccagcttcg cgaccagacg
    20161 ctcacgctgc cattgcagga tttccggcat atgggcgcgg actttgacca cttcggcggt
    20221 gacgccttcc agacgctgct cgatcaatgc tttcagtgcc tgaccttcgg tttcgcgcgc
    20281 gacaataaag tcgtccagcg taccatccag cgccgcgaga atttcagcgg caatggcgtc
    20341 aagatcctgc tcctgggctg ccatcacgcc cggccagcgt agaatatcaa ccgggttgat
    20401 ttccccttcg tcactctgca tttttaccca gttcgcggca gttaccagct gtttagccag
    20461 tttttcgttg aggatcagct caccttgcgc gctaacatct ggctcatagc gcagggtaca
    20521 ttccacttta ccgcgcgtca ggcgagaacg aatacgctcg cgaacgacag gttcaaggct
    20581 acggaactgc tccggcagac gaaagtaagt ttccagataa cgctggttta ccgagcgcat
    20641 ttcccaggtt gcgctccccc attcaccctt gatttcacgc cgggcgtagg cggtcatact
    20701 gcggatcata gacgttcctg tttataaaag gagaggtgga aggattatag ccatcgatgc
    20761 cttgtcagga taggaataac cgccggaagt ccgtataatg cgcagccaca tttgtttcaa
    20821 gccggagatt tcaatatgcg tccagcaggc cgtagcaata atcaggtgcg tcccgttacc
    20881 ctgactcgta actatacaaa acatgcagaa ggctcggtgc tggtcgaatt tggcgatacc
    20941 aaagtgttgt gtaccgcctc tattgaagaa ggcgtgccgc gcttcctgaa aggtcagggc
    21001 cagggctgga tcaccgcaga gtacggcatg ctgccacgtt ctacccacac ccgtaacgct
    21061 cgtgaagcgg cgaaaggtaa gcagggtgga cgcacaatgg aaatccagcg tctgatcgcc
    21121 cgtgctcttc gcgcggcagt agatttgaaa gcgctgggtg agttcaccat tacgctggac
    21181 tgcgacgtgc ttcaggctga tggtggcacg cgtaccgcgt cgattacggg tgcctgcgtg
    21241 gcgctggcag atgcgctaca gaagctggtg gaaaacggca agctgaaaac caatccgatg
    21301 aaagggatgg tagccgcagt ttctgtcgga attgtgaacg gcgaagcggt ttgcgatctg
    21361 gaatacgttg aagactctgc cgcagagacc gacatgaacg tagtgatgac cgaagacggg
    21421 cgcatcattg aagtgcaggg gacggcagaa ggcgagccgt tcacccatga agagctactc
    21481 accttgttgg ctctggcccg agggggaatc gaatccattg tagcgacgca gaaggcggcg
    21541 ctggcaaact gatttttaag gcgactgatg agtcgccttt tttttgtctg tagaaaagta
    21601 agatgaggag cgaaggcatg aaaccatatc agcgccagtt tattgaattt gcgcttggca
    21661 agcaggtgtt aaagtttggc gagtttacgt tgaagtccgg gcgcaaaagc ccctatttct
    21721 tcaacgccgg gctgtttaat accgggcgcg atctggcact gttaggccgt ttttacgctg
    21781 aagcgttggt ggattccggc cttgagttcg atctgctgtt tggccctgct tacaaaggga
    21841 tcccgattgc gaccactacc gccgtggcgc tggcggagca tcatgacctt gacctgccgt
    21901 actgctttaa ccgcaaagag gcaaaagacc acggtgaagg cggcaatctg gttggtagcg
    21961 cgttacaagg acgcgtaatg ctggtagatg atgtgatcac cgccggaacg gcgattcgcg
    22021 aatcgatgga gattattcag gctaatggcg cgacgcttgc tggcgtattg atttcgcttg
    22081 atcgtcagga acgggggcgc ggcgagattt cggcgattca ggaagttgag cgtgattaca
    22141 actgcaaagt gatctctatc atcaccctga aagatctgat tgcctatctg gaagagaagc
    22201 cggaaatggc ggaacatctg gcggcggtta aggcctatcg cgaagagttt ggcgtttaaa
    22261 gaaactcgcc ggatgaaaag tcatccggcg tcatattact gcaactgcgc ggcaattagc
    22321 ggccagcggg cgtcaaaatc atccgtcggg cggtatttaa attcgctgcg gacaaaacgt
    22381 gacagcatac cttcacagaa ggccaggatc tggcttgcca gcagggtttc atcggtggtg
    22441 taaccttcac cctcacgcat tctcttttca cgcaatacct gacgcagctg cgcttcaata
    22501 cgctcgaaca gctggttgat acgcccttgc aggcgatcct gttcaaacat tagcgcatga
    22561 ccagtgagga tgcgggtcag gccaggatta cgctcaccaa aaccgagaag cagcaacaca
    22621 atcagacgca ggcgcgctgt ggtgtctttc tcatctttca gaatcaggtt gatgcgagta
    22681 atcaggctat cttcgataaa ctcaatcagg ctatcgaaca tgcgggtctt actggggaag
    22741 tggcgataca gtgccgcttc ggaaacgccg acagaggcgg ccagttttgc cgtcgtgata
    22801 cgttggcttc catcgctgga ttccagcatc agcgccagag actgaagtat ttcctcgcga
    22861 cggttccttt tcgcagtttg tttttctgcc atgttacaaa atacccctga aaataagcac
    22921 ttgccaggcg gcacccacgc tatgaccgca aacgaaatgt ttgcggctat gttatgacgt
    22981 tattcggatg cgtatgtgtt actgacgacc agagtgacca aagccgcctt caccgcggtc
    23041 ggtggcgtcg aaatcttcca ccagattaaa ttcagcctgt actaccggaa caaaaatcat
    23101 ctgggcgatg cgttcgccag gttgaatggt gaagctgtcc tgaccacggt tccacacgga
    23161 aatcatcaac tggccctgat agtcagaatc gatcaatcct accaggttac caagcacgat
    23221 accgtgctta tgtcccaatc cggagcgcgg cagcatcatt gccgccagtg aaggatcggc
    23281 aatatgaatc gccagcccgg tcggaaccag cgtagtgtca cccggagcca gttctacggc
    23341 gtcgtcgaga caggcacgca ggtcaagtcc ggcagagcca gaggtggcat aagtcgggag
    23401 cggaaattcc ttcccaacgc gcgggtccag aatcttaacg tcgatttttt tcatcataac
    23461 gggtcacgat ctcgtcgagt aataattggc caaggagctc tttgcgctca agcggtaaga
    23521 ctttatctcc gtcctgccag aaaaggtgta atgcgttgtt gtcgctgtta aatccttgag
    23581 ttggctggga aacatcgttc gcgcagatca gatcaaggtt tttacggata cgtttttgcc
    23641 gggcgtattc ttccacatta tttgtttcgg cggcaaatcc aacgacgtag ggtcgatggt
    23701 cttttagtgc ggcaacgcct gcgacgatat cggggttttt aaccattttt attgttaatt
    23761 catcaccctg cgtggcctgc tttttgattt tctctggggc cacggtagct gcgcgataat
    23821 ccgccacggc ggcgcagccg ataaaaatat tttgctgctg tacagaagca ttcacggcgg
    23881 cttccatttc cagcgcggtc atcacatcaa cacgtttaac aaacggtggc gtcggtagtg
    23941 aaaccggacc tgataccagc gtgacgttcg cgccacgacg ggcagcggcg gcggcgatag
    24001 caaaacccat cttgccggag ctgtgattag agatataacg cacgggatcg agcggttcac
    24061 gcgtcgggcc ggcggtaatc ataatgttca gatgtttcag gtcgttgacg ggcgaaaaat
    24121 gcgctaccgc catatccaca atggttaacg gatcgagcat tcgcccagga ccgatatcac
    24181 cacaagcctg actgccactg tctggccccc agatgagcaa accacgggaa gcaagcacct
    24241 ctaaattatg ctgcgtggca gcggcacggt acatctgctg gttcatggcg gggagcacgg
    24301 ctacaggcgc aggtgtagcc agacaaatcg tcgataccag gtcattcgcc attccggcag
    24361 caacacgggc aatcaaatct gccgtggcag gggcgagaat cactaaatca gcccatttac
    24421 ccagctcaat atggcccata gcggcttcgg ctgccgggtc cagcagactg tcggaaacgg
    24481 gataaccaga aaccgcctgc aagctaagtg gggtgataaa ggcttttgcc gcttcggtca
    24541 tggctacgcg gacgtcggcc ccgcgatcgc gcaaacgacg caccagttca ggggttttat
    24601 aggcagcaat accgccgcta acgccgagaa cgattttttt accggccagg ctcatgatga
    24661 tttttcctgt tgggtgacac cagaagttgg cgattttatc acaatacttt tgttgtcgtg
    24721 ccttcacctg agaatcactt tgcgaggcgc tttccaggat tgaaaactgg ccgtcgattt
    24781 aacggaacgg ctatgacagg atgcgagcac cacaaaggag gtgaaggtga aaaacaattc
    24841 acagctgttg atgccgcgcg aaaaaatgct gaagtttggt attagcgcct taacggatgt
    24901 cgagctgctg gcgctatttc tgcgtaccgg aacgcgcggt aaagatgtat taaccctggc
    24961 aaaagagatg ctggagaatt tcggctctct ttatggcttg ttaacctctg aatatgaaca
    25021 atttagtggc gttcatggaa ttggcgtggc gaaatttgcc cagttaaagg ggattgctga
    25081 actggcgcgg cgttactaca acgtgcggat gcgtgaagaa agccctttac tcagcccgga
    25141 gatgacgcgg gaatttttac aaagccagct cacgggtgag gagcgggaga tctttatggt
    25201 gatctttctc gactcacaac accgggttat aacgcatagc cgactttttt ccggcacgct
    25261 aaaccatgtt gaagtccatc ctcgggaaat tatccgcgaa gcgataaaaa taaacgcctc
    25321 ggcgctgatc cttgcacata atcacccttc gggttgtgct gaacccagta aagcggataa
    25381 actcattact gaacggataa taaagagttg tcagttcatg gatttacgcg tgctcgacca
    25441 tatcgtgatt gggcgtggag agtatgtttc ttttgccgaa cgcggctgga tttaacccgc
    25501 tatgcgcgat ccttcgggat ctttgtctgt tcgggacttg agcacatcgc tgagtcagcg
    25561 tatactacgc cacctttgag aatctcgggt ttggcatttg ggcctggcaa tcgagagttc
    25621 acatagaact gcgatgaccg ggctgtaaag cctgacgagg cgccaatacc ccatacgaag
    25681 ctcgagctaa tttgattttt ggagaataga catgtcccga gtctgccaag ttactggcaa
    25741 gcgtccggtg accggtaaca accgttccca cgcactgaac gcgactaaac gccgtttcct
    25801 gccgaacctg cactctcacc gtttctgggt tgagagcgag aagcgttttg tcaccctgcg
    25861 cgtatctgct aaaggtatgc gtgtaatcga taaaaaaggc atcgatacag ttctggctga
    25921 actgcgtgcc cgtggcgaaa agtactaagt acttagagga aataaatcat ggctaaaggt
    25981 attcgtgaga aaatcaagct ggtttcttct gctggtactg gtcacttcta taccactacg
    26041 aagaacaaac gtactaagcc ggaaaaactg gaactgaaaa aattcgatcc agttgttcgt
    26101 cagcacgtga tctacaaaga agcgaaaatc aaataattct cgctttgatg taacaaaaaa
    26161 cctcgctccg gcggggtttt ttgttatctg cttgccccca tattgattgc atctgttcat
    26221 tcctggagat gctatgcctg aattacccga agttgaaacc agccgtcgcg gcatagaacc
    26281 gcatctcgtt ggtgcaacca ttcttcatgc agtggtgcgc aacggacgct tgcgctggcc
    26341 ggtttcagaa gagatctacc gtttaagcga ccaaccagtg cttagcgtgc agcggcgggc
    26401 taaatatttg ctgctggagc tgcctgaggg ctggattatc attcatttgg ggatgtctgg
    26461 cagcctgcgc atccttccag aagaacttcc ccctgaaaag catgaccatg tggatttggt
    26521 gatgagcaac ggtaaagtgc tgcgctacac cgatccgcgc cgctttggtg cctggctgtg
    26581 gaccaaagag ctggaagggc ataatgtgct ggcccatctt ggaccggagc cgctcagcga
    26641 cgatttcaat ggtgagtatc tgcatcagaa gtgcgcgaag aaaaaaacgg cgattaaacc
    26701 gtggctgatg gataacaagc tggtggtagg ggtagggaat atctatgcca gcgaatcact
    26761 gtttgcggcg gggatccatc cggatcggct ggcgtcatca ctgtcgctgg cagagtgtga
    26821 attgttagct cgggtgatta aagcggtgtt gctgcgttcg attgagcagg gtggtacaac
    26881 gctgaaagat tttctgcaaa gtgatggtaa accgggctat ttcgcgcagg aattgcaggt
    26941 ttacgggcga aaaggcgagc cgtgtcgggt gtgcggtacg ccgattgtgg cgactaaaca
    27001 tgcgcagcgg gcaacgtttt attgtcggca gtgccagaag taattcatgc gcgccggatg
    27061 gcataccatc cggcataaac gctacgctaa cttcgccatc agcgcctgat ggacattctc
    27121 cggcaggaaa tgggtgacat cgccctgatg gcgcgccacc tctttcacca acgatgaaga
    27181 gataaacgac cactctttcg acggcatcag aaacacactt tccagttccg gcattaagtg
    27241 gcgattcata tgcgccagct gcatttcata ttcaaaatcc gccaccgcac gcaggccacg
    27301 aatcagcacc gtagcgtgtt gattacgggc gaagttcgcc atcaaatcac taaacccgac
    27361 cacttccacg ttccccagat gcgcggttgc ctgctgtgcc agcgccacac gctcttccag
    27421 ggtaaacatc ggttttttac tggggctggc ggcaatcgcc agaataacgt gatcgaacat
    27481 ttgcgtggcg cgcgtcacga tatcgatatg accattggta atgggatcga aagtaccagg
    27541 ataaatcgcc cgtttttgca taacaacctc aatgcgtttt cggtggcagg taaggttcca
    27601 gcagttgaag cagacgctgt agcgcgccct ggttttgata cagtacttca acggcatgac
    27661 ggccatagaa actacggtaa tcggcgtcgg tgagtaaaga ggacacctct tttgcaagcg
    27721 tagtggcatc ggtaacggta atcagcccgc ttgcctgctc cagccgcgcg caaatgtctt
    27781 taaagttaaa agtatgcggc cccatcaata ccggaatagc gtgtgcggca gcttccagcg
    27841 gattatgccc accacgttca accagtgaac cgccaacaaa ggcgagatcg gcaatgccgt
    27901 acagtaacat caactcgccc atcgtatcgc caaccacaac ctgcgtgctg gtggagggga
    27961 cttcccctga agagcgtgtg atatagctta gtccagcctg gcggacaaga ttaatcgcat
    28021 ccgggaagcg ttctggatga cggggtacca ggatgagcaa taaattcggg aattgctgta
    28081 acaatgcctg atgtgcggcg atcaccacac tctcttcgcc ttcgtgagtg ctggtggcaa
    28141 tccataccgg gcggtgtggt gcccactggc ggcgcagcgt cacggcttta gcagccaact
    28201 gcggcgttac agaaatatcg aatttcaggc taccggtaac ggtcacctga ttattttttg
    28261 cgcccagcgc cacaaaacgt gcaccatctt cttcattttg cgcagcaatc agcgtaatac
    28321 gacgcagcaa gcgacggacg aatttaccca gtttggcata acctgcggcc gagcgggcag
    28381 agagtcgcgc gttagcgatc accagcggaa ttttacgttt gtgtagcgcc gcaatcaggt
    28441 taggccatag ttcggtttcc ataatcaaca ccagtttggg gtcgacttta ttcaggaaac
    28501 ggttgagcgc atcgggcagg tcatacggca gataaacgtg ctgaacatcc ttcccgaaag
    28561 ccgattgtac gcgctccgaa ccggttggcg tcatggttgt aacggtaatc ggtaaatcag
    28621 gataacgatg gcgcagcgcg cgcaccaacg ggatcgccgc cagagtttca ccgacggaga
    28681 cggagtgcag cataatgccg cctggtttta gcggatggcg gtaaaaaccg taacgttcac
    28741 cccagcgttt tcgataggcc ggagccttac gtccgcgcac ccagagccgt atccagatca
    28801 gcggctgaat aaggtagaga agggcggtgt aaagcaattc gagcatagta aatagctgac
    28861 ttatggatgt gctggggatt ctatgtattt agctgtggct ttaccattac ttttcccgtt
    28921 tttgacttaa atagcaattt acccgccaat tcttgctgaa catctatact ttttttgtat
    28981 ttttatgcga ttcattgatt tctgctgtac gtgcaggaag gaatcgcaga gcaacagtga
    29041 aagaatatgg ttgctaatga ttttatttga ttgatttctt tattgaaaat caacaatgtg
    29101 cttaaaaatc attcgggtcg gattgccgcg aaagaagtga tacactagcg cgtcaatatc
    29161 agtgcggtat cagtattcag gtagctgttg agcctggggc ggtagcgtgc tttttctgct
    29221 tcaccttaat cggataatct caacaaaaag agttacttgt ggataagcca tttcgaagaa
    29281 ttttgctcat taagatgcgt tttcatgggg atatgttatt aactactccc gtcattagtt
    29341 cgctgaaaaa aaattaccct gacgcaaaaa tcgatgtgct gctttatcag gacaccatcc
    29401 cgatcctgtc tgaaaatcca gagattaacg cgctctacgg cataaaaaat aaaaaagcaa
    29461 aagcctcaga aaaaattgcc aacttttttc atctcatcaa ggtattacgt gccaataagt
    29521 atgaccttat cgtcaatctt accgatcaat ggatggttgc tatactggtt cgcttattaa
    29581 atgcccgtgt gaaaatttcc caggattatc atcatcggca gtctgctttt tggcgtaaaa
    29641 gtttcaccca tttggtgccg ttgcagggtg gaaatgtggt ggaaagtaac ttatccgtgc
    29701 tgacaccatt gggacttgat tcgttggtga agcagacaac catgagttac ccgcctgcaa
    29761 gctggaaacg tatgcgtcgc gaacttgatc acgctggtgt tggacaaaat tatgtggtta
    29821 tccaacctac ggcgcggcaa atcttcaaat gctgggacaa cgccaagttt tccgctgtga
    29881 ttgatgcctt acatgctcgt ggttatgaag tcgttctgac gtccggcccg gataaagacg
    29941 atctggcctg cgtcaatgaa attgcgcagg gatgccagac gccaccagta acggcgctgg
    30001 ctggaaaggt gaccttcccg gaacttggtg cgttaatcga tcatgcgcag ctgtttattg
    30061 gcgttgattc cgcaccggcg catattgccg ctgcagttaa tacgccgctg atatcgctgt
    30121 ttggtgcgac agaccatatt ttctggcgtc cctggtcaaa taacatgatt caattctggg
    30181 cgggagatta ccgggaaatg ccaacgcgcg atcagcgtga ccgaaatgag atgtatcttt
    30241 cggttattcc ggcggcagat gtcattgctg ctgtcgataa attactgccc tcctccacga
    30301 caggtacgtc gttatgatcg ttgctttttg tttatataaa tattttccct ttggcggttt
    30361 gcagcgtgat tttatgcgta ttgctcagac agtcgccgcc cgaggtcatc atgttcgggt
    30421 ttatacccag tcgtgggaag gcgaatgccc tgatgtattt gaactgatca aagtgccggt
    30481 taaatcgcat accaatcacg ggcgcaatgc ggagtatttt gcctgggtgc aaaaacattt
    30541 acgcgaacat cccgtcgata aagtcgttgg attcaacaaa atgccggggc tggacgttta
    30601 ttatgccgct gatgtttgtt atgccgagaa agtagcgcag gaaaaaggct ttttctatcg
    30661 cctgacgtca cgttatcgcc attatgccgc ctttgagcgg gcaaccttcg aacagggcaa
    30721 gccgacacag ctgctgatgc tgacagataa gcaaatcgcc gatttccaga aacattatca
    30781 gactgaagcg gagcgttttc atattctgcc accggggatt tatcctgatc gtaaatatag
    30841 ccagcagcca gccaatagcc gtgaaatctt ccgtaagaag aatggaataa ccgaacaaca
    30901 atatttattg ttgcaggtcg gttcagactt cacgcgtaaa ggtgtcgatc gttccattga
    30961 agcacttgct tcgttaccgg attcgctgcg ccacaacaca ttgctatatg ttgttgggca
    31021 ggataaaccg cgaaaatttg aggcactggc agaaaaacgc ggcgtgcgca gtaatgttca
    31081 cttcttctcg gggcgcaacg atgtctcgga attaatggcg gcggcggatt tattactgca
    31141 tcctgcctac caggaagcgg cgggaattgt gctgctggaa gcgattactg caggattacc
    31201 ggtactaaca actgccgttt gtggctatgc gcattatatt gtcgacgcta attgcggcga
    31261 ggctattgct gagccattcc gccaggaaac attgaatgag attttacgca aagcgttaac
    31321 gcaatcttca ttgcgccagg cttgggcgga aaatgcgcga cattatgctg atacacaaga
    31381 tttatacagt ctgccagaga aagcggcgga tatcataacg ggtggtctgg atggttgaac
    31441 ttaaagagcc gtttgccacg ttatggcgcg gcaaagatcc ttttgaggaa gttaaaacct
    31501 tgcagggtga ggtatttcgt gaactggaaa ctcgccgtac tctgcgcttt gaaatggcgg
    31561 gcaaaagcta ttttctcaaa tggcatcgcg gcacgaccct gaaagagata atcaaaaatt
    31621 tactctcatt gcggatgcca gtattaggcg ctgaccgcga atggaatgcg attcatcgac
    31681 tgcgggatgt cggcgttgat actatgtatg gggtggcatt tggcgaaaaa ggcatgaatc
    31741 cgctgaccag aacttcattt attattaccg aagatctgac accaaccata agtctggaag
    31801 attactgtgc tgactgggcg accaacccac cagatgttcg cgtaaagcgt atgcttatta
    31861 agcgtgtcgc gacgatggtg cgcgatatgc atgctgcggg cattaatcac cgtgactgtt
    31921 atatctgtca tttcctgctg cacttgcctt tttccggtaa ggaagaggag ttaaaaattt
    31981 cggtaattga cctgcaccgg gcgcagcttc gcacgcgcgt tccacgtcgt tggcgcgata
    32041 aagatcttat tgggctttat ttttcttcga tgaatatcgg cctgactcag cgggatatct
    32101 ggcggtttat gaaagtgtat tttgccgccc cgcttaaaga cattctcaag ctggaacaag
    32161 gactgctgtc gcaagcagaa gcaaaagcca caaaaatcag ggaaagaacg attcgaaaat
    32221 cgttgtaatt tccggagaga aatatgagtg cccactattt taatccacaa gagatgatca
    32281 ataagacaat catcttcgat gaaaggccag cggcgtcagt ggcatcatca ttccatgttg
    32341 cttatggcat tgataaaaac tttctttttg gttgtggtgt ttcaatcacg tcagttttgt
    32401 tacataacaa cgacgtgagt tttgttttcc acgtttttat tgatgatatc cctgaagccg
    32461 atatccagcg tttagcccaa ttggcgaaaa gctatcgtac ctgtatccag atccatctgg
    32521 taaattgtga acggcttaag gcattaccga cgaccaaaaa ttggtctatt gccatgtatt
    32581 tccgttttgt aattgcagat tactttattg atcaacaaga taagatcctt tacctggatg
    32641 ctgatatcgc ctgtcaggga aacttaaagc cgctgataac aatggatctt gccaataacg
    32701 ttgctgctgt tgttactgaa cgcgatgcta actggtggtc gttacggggt caaagtctgc
    32761 agtgtaatga acttgaaaag ggttacttta attcaggtgt cctgttaatt aatacactag
    32821 cgtgggcgca ggagtccgtt tctgctaaag cgatgtcgat gcttgctgat aaagccatcg
    32881 tttcccgttt aacctatatg gatcaagata tccttaatct tatcctgtta gggaaagtta
    32941 aattcattga tgctaaatac aatacgcaat ttagtttaaa ttatgaatta aaaaaatcat
    33001 ttgtttgtcc aattaatgat gaaaccgtat taattcatta tgtcggcccg acaaaaccct
    33061 ggcattactg ggccggttat ccaagtgcgc aaccttttat caaagccaaa gaagcatcgc
    33121 cctggaaaaa tgaaccgtta atgcggccag ttaactcaaa ctatgctcgt tattg
//
LOCUS       DAPGUL010000045        33048 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.045, whole genome shotgun sequence.
ACCESSION   DAPGUL010000045 DAPGUL010000000
VERSION     DAPGUL010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 33048)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33048)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33048
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.045"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(11..259)
                     /gene="hybG"
                     /locus_tag="RHX21_002267"
     CDS             complement(11..259)
                     /gene="hybG"
                     /locus_tag="RHX21_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation factor HybG"
                     /protein_id="HDV1987438.1"
                     /translation="MCIGVPGQVLAVGEDIHQLAQVEVCGIKRDVNIALICEGNPADL
                     LGQWVLVHVGFAMSIIDEDEAKATLDALRQMDYDITSA"
     gene            complement(272..613)
                     /gene="hypA"
                     /locus_tag="RHX21_002268"
     CDS             complement(272..613)
                     /gene="hypA"
                     /locus_tag="RHX21_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HDV1987439.1"
                     /translation="MHELSLCQSAVEIIQRQAEQHDVKRVTAVWLEIGALSCVEESAV
                     RFSFEIVCHGTVAQGCDLHIVYKPAQAWCWDCSQVVEIHQHDAQCPICHGERLRVDTG
                     DSLIVKSIEVE"
     gene            complement(606..1094)
                     /gene="hybE"
                     /locus_tag="RHX21_002269"
     CDS             complement(606..1094)
                     /gene="hybE"
                     /locus_tag="RHX21_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase-2 assembly chaperone"
                     /protein_id="HDV1987440.1"
                     /translation="MTEEIAGFQTSPKAQVQAAFEEIARRSMHDLSFLHPSMPVYVSD
                     FTLFEGQWTGCVITPWMLSAVIFPGPDQLWPLRKVSEKIGLQLPYGTMTFTVGELDGV
                     SQYLSCSLMSPLSHSMSIEEGQRLTDDCARMILSLPVTNPDVPHAGRRALLFGRRSGE
                     NA"
     gene            complement(1087..1581)
                     /locus_tag="RHX21_002270"
     CDS             complement(1087..1581)
                     /locus_tag="RHX21_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HyaD/HybD family hydrogenase maturation
                     endopeptidase"
                     /protein_id="HDV1987441.1"
                     /translation="MRILVLGVGNILLTDEAIGVRIVEALEQRYILPDYVEILDGGTA
                     GMELLGDMANRDHLIIADAIVSKKSAPGTMMILRDEEVPALFTNKISPHQLGLADVLS
                     ALRFTGEFPKKLTLVGVIPESLEPHIGLTPTVEAMIEPALEQVLAALRESGVEAIPRE
                     AIHD"
     gene            complement(1581..3284)
                     /gene="hybC"
                     /locus_tag="RHX21_002271"
     CDS             complement(1581..3284)
                     /gene="hybC"
                     /locus_tag="RHX21_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 large subunit"
                     /protein_id="HDV1987442.1"
                     /translation="MSQRITIDPVTRIEGHLRIDCEIENGVVSKAWASGTMWRGMEEI
                     VKNRDPRDAWMIVQRICGVCTTTHALSSVRAAESALNIDVPVNAQYIRNIILAAHTTH
                     DHIVHFYQLSALDWVDITSALQADPTKASEMLKGVSTWHLNSPEEFTKVQNKIKDLVA
                     SGQLGIFANGYWGHPAMKLPPEVNLIAVAHYLQALECQRDANRVVALLGGKTPHIQNL
                     AVGGVANPINLDGLGVLNLERLMYIKSFIDKLSDFVEQVYKVDTAVIAAFYPEWLTRG
                     KGAVNYLSVPEFPTDSKNGSFLFPGGYIENADLSSYRPITSHSDEYLIKGIQESAKHS
                     WYKDEAPQAPWEGTTIPAYDGWSDDGKYSWVKSPTFYGKTVEVGPLANMLVKLAAGRE
                     STQNKLNEIVAIYQKLTGNTLEVAQLHSTLGRIIGRTVHCCELQDILQNQYSALITNI
                     GKGDHTTFVKPNIPATGEFKGVGFLEAPRGMLSHWMVIKDGIISNYQAVVPSTWNSGP
                     RNFNDDVGPYEQSLVGTPVADPNKPLEVVRTIHSFDPCMACAVHVVDADGNEVVSVKV
                     L"
     gene            complement(3281..4459)
                     /gene="hybB"
                     /locus_tag="RHX21_002272"
     CDS             complement(3281..4459)
                     /gene="hybB"
                     /locus_tag="RHX21_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase cytochrome b subunit"
                     /protein_id="HDV1987443.1"
                     /translation="MSHDPQPLGGKIISKPVMIFGPLIVICMLLIVKRLVFGLGSVSD
                     LNGGFPWGVWIAFDLLIGTGFACGGWALAWAVYVFNRGQYHPLVRPALLASLFGYSLG
                     GLSITIDVGRYWNLPYFYIPGHFNVNSVLFETAVCMTIYIGVMALEFAPALFERLGWK
                     VSLQRLNKVMFFIIALGALLPTMHQSSMGSLMISAGYKVHPLWQSYEMLPLFSLLTAF
                     IMGFSIVIFEGSLVQAGLRGNGPDEKSLFVKLTNTISVLLAIFIVLRFGELIYRDKLS
                     LAFAGDFYSVMFWIEVLLMLFPLVVLRVAKLRNDSRMLFLSALSALLGCATWRLTYSL
                     VAFNPGGGYAYFPTWEELLISIGFVAIEICAYIVLIRLLPILPPLKQNDHNRHEASKA
                     "
     gene            complement(4449..5435)
                     /gene="hybA"
                     /locus_tag="RHX21_002273"
     CDS             complement(4449..5435)
                     /gene="hybA"
                     /locus_tag="RHX21_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 operon protein HybA"
                     /protein_id="HDV1987444.1"
                     /translation="MNRRNFIKAASCGALLTGALPSVSHAAAENRPPIPGSLGMLYDS
                     TLCVGCQACVTKCQDINFPERNPQGEQTWSNNDKLSPYTNNIIQVWTSGTGVNKDQEE
                     NGYAYIKKQCMHCVDPNCVSVCPVSALKKDPKTGIVHYDKDVCTGCRYCMVACPYNVP
                     KYDYNNPFGALHKCELCNQKGVERLDKGGLPGCVEVCPAGAVIFGTREELMAEAKKRL
                     ALKPGSEYHYPRQTLKSGDTYLHTVPKYYPHLYGEKEGGGTQVLVLTGVPYENLDLPK
                     LDDLSTGARSENIQHTLYKGMMLPLAVLAGLTVLVRRNTKNDHHDGGDDHES"
     gene            complement(5438..6556)
                     /gene="hybO"
                     /locus_tag="RHX21_002274"
     CDS             complement(5438..6556)
                     /gene="hybO"
                     /locus_tag="RHX21_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 small subunit"
                     /protein_id="HDV1987445.1"
                     /translation="MTGDNTLIHSHGINRRDFMKLCAALAATMGLSSKAAAEMAESVT
                     NPQRPPVIWIGAQECTGCTESLLRATHPTVENLVLETISLEYHEVLSAAFGHQVEENK
                     HNALEKYKGQYVLVVDGSIPLKDNGIYCMVAGEPIVDHIRKAAEGAAAIIAIGSCSAW
                     GGVAAAGVNPTGAVSLQEVLPGKTVINIPGCPPNPHNFLATVAHIITYGKPPKLDDKN
                     RPTFAYGRLIHEHCERRPHFDAGRFAKEFGDEGHREGWCLYHLGCKGPETYGNCSTLQ
                     FCDVGGVWPVAIGHPCYGCNEEGIGFHKGIHQLANVENQTPRSQKPDVNAKEGGNVSA
                     GAIGLLGGVVGLVAGVSVMAVRELGRQQKKDNADSRGE"
     gene            complement(6745..7032)
                     /locus_tag="RHX21_002275"
     CDS             complement(6745..7032)
                     /locus_tag="RHX21_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2623 domain-containing protein"
                     /protein_id="HDV1987446.1"
                     /translation="MNNHFGKGLMAGLKATHADSAVNVTKFCADYKRGFVLGYSHRMY
                     EKTGDRQLSAWEAGILTRRYGLDKEMVMDFFRENNSCSTLRFFMAGYRLEN"
     gene            complement(7151..8038)
                     /locus_tag="RHX21_002276"
     CDS             complement(7151..8038)
                     /locus_tag="RHX21_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311911.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HDV1987447.1"
                     /translation="MPRLTAKDFPQELLDYYDYYAHGKISKREFLNLAAKYAVGGMTA
                     LALFDLLKPNYALATQVEFTDPEIVAEYITYPSPNGHGEVRGYLVKPAKMSGKTPAVV
                     VVHENRGLNPYIEDVARRVAKAGYIALAPDGLSSVGGYPGNDDKGRELQQQVDPTKLM
                     NDFFAAIEFMQRYPQAAGKVGITGFCYGGGVSNAAAVAYPELACAVPFYGRQAPTADV
                     AKIEAPLLLHFAELDTRINEGWPAYEAALKANNKVYEAYIYPGVNHGFHNDSTPRYDK
                     SAADLAWQRTLKWFDKYLS"
     gene            8195..9235
                     /gene="gpr"
                     /locus_tag="RHX21_002277"
     CDS             8195..9235
                     /gene="gpr"
                     /locus_tag="RHX21_002277"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HDV1987448.1"
                     /translation="MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNALES
                     QRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDM
                     WPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
                     KALYVGISSYSPERTQKMVELLHEWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVG
                     CIAFTPLAQGLLTGKYLNGIPQDSRMYREGNKVRGLTPKMLTEANLNSLRLLNEMAQQ
                     RGQSMAQMALSWLLKDERVTSVLIGASRAEQLEENVQALNNLTFSTEELAQIDQHIAD
                     GELNLWQASSDK"
     gene            complement(9275..9769)
                     /locus_tag="RHX21_002278"
     CDS             complement(9275..9769)
                     /locus_tag="RHX21_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00645 family protein"
                     /protein_id="HDV1987449.1"
                     /translation="MERFLENAMYASRWLLAPVYFGLSLALVALALKFFQEIIHVLPN
                     IFSMAESDLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISENKEKLNWLGKMDA
                     TSLKNKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLT
                     RHNH"
     gene            9960..10844
                     /gene="yghA"
                     /locus_tag="RHX21_002279"
     CDS             9960..10844
                     /gene="yghA"
                     /locus_tag="RHX21_002279"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(+)-dependent aldehyde reductase"
                     /protein_id="HDV1987450.1"
                     /translation="MSHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPVPDCGEKTYVGS
                     GRLKDRKALVTGGDSGIGRAAAIAYAREGADVAISYLPVEEEDAQDVKKIIEECGRKA
                     VLLPGDLSDEKFARSLVHEAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAIN
                     VFALFWLTQEAIPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVA
                     EKGIRVNIVAPGPIWTALQISGGQTQDKIPQFGQQTPMKRAGQPAELAPVYVYLASQE
                     SSYVTAEVHGVCGGEHLG"
     gene            complement(11116..11541)
                     /gene="exbD"
                     /locus_tag="RHX21_002280"
     CDS             complement(11116..11541)
                     /gene="exbD"
                     /locus_tag="RHX21_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB system transport protein ExbD"
                     /protein_id="HDV1987451.1"
                     /translation="MAMHLNENLDDNGEMHDINVTPFIDVMLVLLIIFMVAAPLATVD
                     VKVNLPASTSTPQPRPEKPVYLSVKADNSMFIGNDPVTDETMITALNALTEGKKDTTI
                     FFRADKTVDYETLMKVMDTLHQAGYLKIGLVGEETAKAK"
     gene            complement(11548..12282)
                     /gene="exbB"
                     /locus_tag="RHX21_002281"
     CDS             complement(11548..12282)
                     /gene="exbB"
                     /locus_tag="RHX21_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system-associated acyl-CoA thioesterase"
                     /protein_id="HDV1987452.1"
                     /translation="MGNNLMQTDLSVWGMYQHADIVVKCVMIGLILASVVTWAIFFSK
                     SVEFFNQKRRLKREQQLLAEARSLNQANDIAADFGSKSLSLHLLNEAQNELELSEGSD
                     DNEGIKERTSFRLERRVAAVGRQMGRGNGYLATIGAISPFVGLFGTVWGIMNSFIGIA
                     QTQTTNLAVVAPGIAEALLATAIGLVAAIPAVVIYNVFARQIGGFKAMLGDVAAQVLL
                     LQSRDLDLEASAAAHPVRVAQKLRAG"
     gene            12534..13721
                     /gene="metC"
                     /locus_tag="RHX21_002282"
     CDS             12534..13721
                     /gene="metC"
                     /locus_tag="RHX21_002282"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HDV1987453.1"
                     /translation="MADKKLDTQLVNAGRSKKYTLGAVNSVIQRASSLVFDSVEAKKH
                     ATRNRANGELFYGRRGTLTHFSLQQAMCELEGGAGCALFPCGAAAVANSILAFVEQGD
                     HVLMTNTAYEPSQDFCSKILSKLGVTTSWFDPLIGADIVKHLQPNTKIVFLESPGSIT
                     MEVHDVPAIVAAVRSVVPDAIIMIDNTWAAGVLFKALDFGIDVSIQAATKYLVGHSDA
                     MIGTAVCNARCWEQLRENAYLMGQMVDADTAYITSRGLRTLGVRLRQHHESSLKVAEW
                     LAEHPQVARVNHPALPGSKGHEFWKRDFTGSSGLFSFVLKKKLSNEELANYLDSFSLF
                     SMAYSWGGYESLILANQPEHIAAIRPQGEIDFSGTLIRLHIGLEDVDDLIADLDAGFA
                     RIV"
     gene            13861..14520
                     /locus_tag="RHX21_002283"
     CDS             13861..14520
                     /locus_tag="RHX21_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDV1987454.1"
                     /translation="MAVIQDIIAALWQHDFAALADPHIVSVVYFVMFATLFLENGLLP
                     ASFLPGDSLLILAGALIAQGVMDFLPTIAILTAAASLGCWLSYIQGRWLGNTKTVKGW
                     LAQLPAKYHQRATCMFDRHGLLALLAGRFLAFVRTLLPTMAGISGLPNRRFQFFNWLS
                     GLLWVSVVTSFGYALSMIPFVKRHEDQVMTFLMILPIALLTAGLLGTLFVVIKKKYCN
                     A"
     gene            complement(14560..15459)
                     /gene="yqhC"
                     /locus_tag="RHX21_002284"
     CDS             complement(14560..15459)
                     /gene="yqhC"
                     /locus_tag="RHX21_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001407451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YqhC"
                     /protein_id="HDV1987455.1"
                     /translation="MKREEICRLLADKVNKLKNKENSLSELLPDVRLLYGETPFARTP
                     VMYEPGIIILFSGHKIGYINERVFRYDANEYLLLTVPLPFECETYATSEVPLAGLRLN
                     VDILQLQELLMDIGEDEHFQPSMAASGINSATLSEEILCAAERLLDVMERPLDARILG
                     KQIIREILYYVLTGPCGGALLALVSRQTHFSLISRVLKRIENKYTENLSVEQLAAEAN
                     MSVSAFHHNFKSVTSTSPLQYLKNYRLHKARMMIIHDGMKASAAAMRVGYESASQFSR
                     EFKRYFGVTPGEDAARMRAMQGN"
     gene            15653..16816
                     /gene="yqhD"
                     /locus_tag="RHX21_002285"
     CDS             15653..16816
                     /gene="yqhD"
                     /locus_tag="RHX21_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HDV1987456.1"
                     /translation="MNNFNLHTPTRILFGKGAIAGLREQIPHDARVLITYGGGSVKKT
                     GVLDQVLDALKGMDVLEFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTK
                     FIAAAANYPENIDPWHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDK
                     QAFHSAHVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAE
                     GILLTLIEDGPKALKEPENYDVRANVMWGATQALNGLIGAGVPQDWATHMLGHELTAM
                     HGLDHAQTLAIVLPALWNEKRETKRAKLLQYAERVWNITEGSDDERIDAAIAATRNFF
                     EQLGVPTHLSDYGLDGSSIPALLKKLEEHGMTQLGENHDITLDVSRRIYEAAR"
     gene            16921..17748
                     /gene="dkgA"
                     /locus_tag="RHX21_002286"
     CDS             16921..17748
                     /gene="dkgA"
                     /locus_tag="RHX21_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417485.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-didehydrogluconate reductase DkgA"
                     /protein_id="HDV1987457.1"
                     /translation="MANPTVIKLQDGNVMPQLGLGVWQASNEEVITAIQKALEVGYRS
                     IDTAAAYKNEEGVGKALKNASVNREELFITTKLWNDDHKRPREALLDSLKKLQLDYID
                     LYLMHWPVPAIDHYVEAWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVTPVINQ
                     IELHPLMQQRQLHAWNATHKIQTESWSPLAQGGKGVFDQKVIRDLADKYGKTPAQIVI
                     RWHLDSGLVVIPKSVTPSRIAENFDVWDFRLDKDELGEIAKLDQGKRLGPDPDQFGG"
     gene            17948..18874
                     /locus_tag="RHX21_002287"
     CDS             17948..18874
                     /locus_tag="RHX21_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjP/YqhG family protein"
                     /protein_id="HDV1987458.1"
                     /translation="MKIILLFLAALASFTVHAQPPSLTVEQTVRHIYQNYKSDATAPY
                     FGETGERAITSARIQQALTLNDNLTLPGNIGWLDYDPVCDCQDFGDLVLESVAITQTD
                     ADHADAVVRFRIFKDDKEKTTQTLKMVAENGRWVIDDIVSNHGSVLQAVNSENEKTLA
                     ALASLQKEQPEAFVAELFEHIADYSWPWTWVVSDSYRQAVNAFYKTTFKTANNPDEDM
                     QIERQFIYDNPICFGEESLFSRVDEIRVLEKTADSARIHVRFTLTNGNNEEQELVLQR
                     REGKWEIADFIRPNSGSLLKQIEAKTAARLKQ"
     gene            18925..19182
                     /gene="yqhH"
                     /locus_tag="RHX21_002288"
     CDS             18925..19182
                     /gene="yqhH"
                     /locus_tag="RHX21_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein YqhH"
                     /protein_id="HDV1987459.1"
                     /translation="MKTIFTVGAVVLATCLLSGCVNEQKVNQLASNVQTLNAKIARLE
                     QDMKALRPQIYAAKSEANRANTRLDAQDYFDCLRCLRMYAE"
     gene            complement(19225..21444)
                     /locus_tag="RHX21_002289"
     CDS             complement(19225..21444)
                     /locus_tag="RHX21_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HDV1987460.1"
                     /translation="MSSISLIQPDRDLFSWPQYWAACFGPAPFLPMSREEMDQLGWDS
                     CDIILVTGDAYVDHPSFGMAICGRMLEAQGFRVGIIAQPDWSSKDDFMRLGKPNLFFG
                     VTAGNMDSMINRYTADRRLRHDDAYTPDNVAGKRPDRATLVYTQRCKEAWKDVPVILG
                     GIEASLRRTAHYDYWSDTVRRSVLVDSKADMLMFGNGERPLVEVAHRLAMGEPISEIR
                     DVRNTAIIVKEALPGWSGVDSTRLDTPGKIDPIPHPYGEDLPCADNKPVAPKKQEAKA
                     VTVQPPRPKPWEKTYVLLPSFEKVKGDKVLYAHASRILHHETNPGCARALMQKHGDRY
                     VWINPPAIPLSTEEMDSVFALPYKRVPHPAYGNARIPAYEMIRFSVNIMRGCFGGCSF
                     CSITEHEGRIIQSRSEDSIINEIEAIRDTVPGFTGVISDLGGPTANMYMLRCKSPRAE
                     QTCRRLSCVYPDICPHMDTNHEPTINLYRRARDLKGIKKILIASGVRYDIAVEDPRYI
                     KELATHHVGGYLKIAPEHTEEGPLSKMMKPGMGSYDRFKELFDTYSKQAGKEQYLIPY
                     FISAHPGTRDEDMVNLALWLKKHRFRLDQVQNFYPSPLANSTTMYYTGKNPLAKIGYK
                     SEDVFVPKGDKQRRLHKALLRYHDPANWPLIRQALEAMGKKHLIGSRRDCLVPAPTIE
                     EMREARRQNRNTRPALTKHTPMATQRQTPATAKKASSTQSRPVNAGAKKRPKAAVGR"
     gene            complement(21555..22967)
                     /gene="ftsP"
                     /locus_tag="RHX21_002290"
     CDS             complement(21555..22967)
                     /gene="ftsP"
                     /locus_tag="RHX21_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsP"
                     /protein_id="HDV1987461.1"
                     /translation="MSLSRRQFIQASGIALCAGAVPLKASAAGQQQPLPVPPLLESRR
                     GQPLFMTVQRAHWSFTPGTRASVWGINGRYLGPTIRVWKGDDVKLIYSNRLTENVSMT
                     VAGLQVPGPLMGGPARMMSPNADWAPVLPIRQNAATLWYHANTPNRTAQQVYNGLAGM
                     WLVEDEVSKSLPIPNHYGVDDFPVIIQDKRLDNFGTPEYNEPGSGGFVGDTLLVNGVQ
                     SPYVEVSRGWVRLRLLNASNSRRYQLQMSDGRPLHVISGDQGFLPAPVSVKQLSLAPG
                     ERREILVDMSNGDEVSITCGEAASIVDRIRGFFEPSSILVSTLVLTLRPTGLLPLVTD
                     SLPMRLLPTEIMAGSPIRSRDISLGDDPGINGQLWDVNRIDVTAQQGTWERWTVRADE
                     PQAFHIEGVMFQIRNVNGAMPFPEDRGWKDTVWVDGQVELLVYFGQPSWAHFPFYFNS
                     QTLEMADRGSIGQLLVNPVP"
     gene            complement(23042..23779)
                     /gene="plsC"
                     /locus_tag="RHX21_002291"
                     /gene_synonym="parF"
     CDS             complement(23042..23779)
                     /gene="plsC"
                     /locus_tag="RHX21_002291"
                     /gene_synonym="parF"
                     /EC_number="2.3.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acylglycerol-3-phosphate O-acyltransferase"
                     /protein_id="HDV1987462.1"
                     /translation="MLYIFRLIITVIYSILVCVFGSIYCLFSPRNPKHVATFGHMFGR
                     LAPLFGLKVECRKPADAESYGNAIYIANHQNNYDMVTASNIVQPPTVTVGKKSLLWIP
                     FFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRISIWMFPEGTRSRGRGLLPFK
                     TGAFHAAIAAGVPIIPVCVSTTSNKINLNRLHNGLVIVEMLPPIDVSQYGKDQVRELA
                     AHCRSIMEQKIAELDKEVAEREAAGKV"
     gene            complement(24012..26270)
                     /gene="parC"
                     /locus_tag="RHX21_002292"
     CDS             complement(24012..26270)
                     /gene="parC"
                     /locus_tag="RHX21_002292"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HDV1987463.1"
                     /translation="MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRR
                     IVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDSACYEAMVLMAQPFSYRYPLVDG
                     QGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR
                     LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTE
                     AEIITSRAEIRKIYENGRGSVRMRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRN
                     KKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGL
                     DGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEI
                     IRNEDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGI
                     LASERKMNNLLKKELQADAQAYGDDRRSPLQEREEAKAMSEHDMLPSEPVTIVLSQMG
                     WVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITLPSARGQ
                     GEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITL
                     PENAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARG
                     EDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDRVEID
                     SPRRASSGDSEE"
     gene            complement(26816..27298)
                     /locus_tag="RHX21_002293"
     CDS             complement(26816..27298)
                     /locus_tag="RHX21_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDV1987464.1"
                     /translation="MTNLTLDVNIIDFPSIPVAMLPHRCSPELLNYSVAKFIMWRKET
                     GLSPVNQSQTFGVAWDDPATTAPEAFRFDICGSVSEPIPDNRYGVSNGELTGGRYAVA
                     RHVGELDDISHTIWGIIRHWLPASGEKMRKAPILFHYTNLAEGVTEQRLETDVYVPLA
                     "
     gene            complement(27351..27743)
                     /gene="ygiW"
                     /locus_tag="RHX21_002294"
     CDS             complement(27351..27743)
                     /gene="ygiW"
                     /locus_tag="RHX21_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OB fold stress tolerance protein YgiW"
                     /protein_id="HDV1987465.1"
                     /translation="MKKFAAVIAVMALCSAPVMAAEQGGFSGPSATQSQAGGFQGPNG
                     SVTTVESAKSLRDDTWVTLRGNIVERISDDLYVFKDASGTINVDIDHKRWNGVTVTPK
                     DTVEIQGEVDKDWNSVEIDVKQIRKVNP"
     gene            27895..28554
                     /gene="qseB"
                     /locus_tag="RHX21_002295"
     CDS             27895..28554
                     /gene="qseB"
                     /locus_tag="RHX21_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator QseB"
                     /protein_id="HDV1987466.1"
                     /translation="MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAP
                     YDAVILDLTLPGMDGRDILREWREKGQREPVLILTARDALEERVEGLRLGADDYLCKP
                     FALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
                     LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGE
                     K"
     gene            28551..29900
                     /gene="qseC"
                     /locus_tag="RHX21_002296"
     CDS             28551..29900
                     /gene="qseC"
                     /locus_tag="RHX21_002296"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_306641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     QseC"
                     /protein_id="HDV1987467.1"
                     /translation="MKFTQRLSLRVRLTLIFLILASVTWLLSSFVAWKQTTDNVDELF
                     DTQLMLFAKRLSTLDLNEINAADRMAQTPNKLKHGHVDDDALTFAIFTHDGRMVLNDG
                     DNGEDIPYSYQREGFADGQLVGDKDQWRFVWMTSPDGKYRIVVGQEWEYREDMALAIV
                     AGQLIPWLVALPIMLIIMMVLLGRELAPLNKLALALRMRDPDSEKPLNATGVPSEVRP
                     LVESLNQLFARTHAMMVRERRFTSDAAHELRSPLTALKVQTEVAQLSDDDPQARKKAL
                     LQLHYGIDRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLQSSVMDIYHTAQQAKID
                     VRLTLNAHGIKRTGQPLLLSLLVRNLLDNAVRYSPQGSVIDVTLNADNFIVRDNGPGV
                     MPEALARIGERFYRPPGQTATGSGLGLSIVQRIAKLHGMNVEFGNAEQGGFEAKVSW"
     gene            complement(29946..30278)
                     /locus_tag="RHX21_002297"
     CDS             complement(29946..30278)
                     /locus_tag="RHX21_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2645 family protein"
                     /protein_id="HDV1987468.1"
                     /translation="MLKHKIQTIFEALLYIMLTYWLIDAFFAFNKYDWMLESGGNICS
                     IPSVSGEDRILQAMIAAFFLLTPLIILILRKLFMREMFEFWVYVFSLGICLVCGWWLF
                     WGRFIFCY"
     gene            30597..31178
                     /gene="mdaB"
                     /locus_tag="RHX21_002298"
     CDS             30597..31178
                     /gene="mdaB"
                     /locus_tag="RHX21_002298"
                     /EC_number="1.6.5.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH:quinone oxidoreductase MdaB"
                     /protein_id="HDV1987469.1"
                     /translation="MSNILIINGAKKFAHSNGQLNDTLTEVADGTLRDLGHDVRIVRA
                     DSDYVVKAEVQNFLWADVVIWQMPGWWMGAPWTVKKYIDDVFTEGHGTLYASDGRTRK
                     DPSKKYGSGGLVQGKKYMLSLTWNAPMEAFTEKDQFFHGVGVDGVYLPFHKANQFLGM
                     EPLPTFIANDVIKMPDVPRYTEEYRKHLVEIFG"
     gene            31209..31523
                     /locus_tag="RHX21_002299"
     CDS             31209..31523
                     /locus_tag="RHX21_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDV1987470.1"
                     /translation="MLTVIAEIRTRPGQHHRQAVLDQFAKIVPTVLKEEGCHGYAPMV
                     DCAAGVSFQSMAPDSIVMIEQWESIAHLEAHLQTPHMKAYSEAIKGDVLEMNIRILQP
                     GI"
     gene            complement(31570..32901)
                     /locus_tag="RHX21_002300"
     CDS             complement(31570..32901)
                     /locus_tag="RHX21_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1987471.1"
                     /translation="MKLTINEKIGFGAGNMAIAIVMMSLAMIITYFYTDVFGLKPVDL
                     GILLFSVRILDAVIDPVVGTMTDITNTRWGKYRPWLLFMSIPFGISIWLMFTTPDTDY
                     SVKLLWAWATYVLLTLTYTLIAIPYVSLISVITDDPQERLSANGYRFVMTKIAMFAVT
                     IIVPLSAMYLGKNNVQLGYQIAMGTMGILATCLCLYCFFSVRERIYHPKPSLGMAAQF
                     RLLIKNDQWLILGAVIAIIMFGGIIRNSVAAYYAKYYLSGGDALISPFLTSGVIASVL
                     AMIACTWLTRLYDKIKIFRYTQLLAFVVGGAMYFVQPNSIVLAFTFYIVVTFLTDIQL
                     PIYWASIAESVDYGEMKTGQRVSGLAFGGILFFQKFGMGLAGGFIGIALAYLDYQPGV
                     EQTPQALWGICLLMTIIPAILNLLTGLIMRFYLINNEYYEQIKARLQTAEE"
BASE COUNT         8319 a         8717 c         8229 g         7783 t
ORIGIN      
        1 aagctaatca tcacgcgctg gtaatgtcgt aatccatttg gcgcagtgcg tctaatgtgg
       61 ctttggcttc atcttcgtcg atgatgctca tggcaaatcc gacgtgtacc agcacccact
      121 ggcccagcag atcggcaggg ttaccttcac aaatcagggc gatattcacg tcgcgcttga
      181 taccacatac ttcaacctgc gcaagctggt gaatatcttc accgacagcc agcacctggc
      241 ctggaacgcc aatacacatt attaactccg gttattcaac ttcaatactt ttgacgatca
      301 gcgaatcgcc ggtatcgaca cgcaaccgct cgccatgaca gatcggacac tgcgcatcgt
      361 gctgatgaat ctccaccacc tggctgcaat cccagcacca ggcctgggcg ggtttataga
      421 cgatatgtaa atcgcaccct tgcgccaccg ttccgtggca gacaatttca aaactaaaac
      481 ggacggcgct ctcctcaacg caggagagcg cgccaatttc cagccacacg gcggtgacgc
      541 gcttaacatc gtgctgctcc gcctgccgtt ggataatttc aacggcgctc tggcaaagcg
      601 acaactcatg cattttcgcc actcctgcga ccaaacagca gggcgcgacg ccctgcgtgt
      661 ggtacatccg gattcgtgac tggcagcgaa aggatcattc gtgcgcagtc atccgtcagg
      721 cgttggccct cttcaatcga catactgtgc gaaagcggtg acatcagcga acaggagagg
      781 tattgcgaaa caccgtccag ttcgccaacg gtaaaggtca tggtgccata cggcagttgc
      841 agaccaattt tttcactcac tttgcgcagc ggccagagtt gatccgggcc ggggaagata
      901 actgcactca gcatccacgg ggtgatcaca caccccgtcc actgaccttc gaacagcgta
      961 aaatcagaaa catacaccgg cattgaagga tgcagaaaag agagatcgtg catcgaacgc
     1021 cgggcaattt cttcaaacgc tgcctgtact tgcgccttcg gggaggtctg gaaacctgct
     1081 atctcttcag tcatgaatcg cctcccgtgg gatggcttcc acgcctgatt cgcgcagcgc
     1141 agccagaacc tgctcaagcg caggttcaat cattgcttca accgtcggcg ttaagccgat
     1201 gtgtggctcc agcgattccg ggatcacgcc gaccagggtc agctttttcg gaaactcgcc
     1261 ggtgaagcgc agggccgaca agacgtcggc caggccaagc tgatgcggag agattttgtt
     1321 ggtaaacaac gccggaactt cttcatcccg caggatcatc atcgttcccg gcgcgctctt
     1381 cttcgacaca atggcatccg caataatcag atgatcgcga tttgccatgt cgccaagcag
     1441 ctccattccc gccgtgccgc catcgaggat ctcaacataa tccggcagaa tgtatcgttg
     1501 ctctaacgct tcgacaatcc gcacaccgat ggcttcatcg gtcagcaaaa tattgccgac
     1561 ccctaagact aaaatacgca ttacagaacc ttcactgaaa ccacttcgtt gccgtcggca
     1621 tccactacgt gtaccgcaca ggccatgcac gggtcgaagg agtgaatggt acgcaccact
     1681 tccagcggtt tattcggatc agcaaccggt gtacccacca gcgactgctc gtaaggaccg
     1741 acgtcatcat tgaagttacg cggaccagag ttccaggttg atggaacaac tgcctggtag
     1801 ttgctgatga taccgtcttt gatcaccatc cagtgagaga gcataccgcg cggcgcttcg
     1861 aggaagccaa cacctttgaa ctcacccgtt gccggaatgt tcggtttcac aaaggtggtg
     1921 tgatcgcctt tgccgatatt ggtgatcagt gcactgtatt ggttttgcag gatatcctgc
     1981 aattcacagc agtgaacggt acgaccaata atacggccca gcgtggagtg cagctgtgcc
     2041 acttccagcg tgttgccagt cagtttctga taaatcgcaa cgatttcatt cagtttgttc
     2101 tgggtagatt ctcgacctgc cgccagtttc accagcatat tagccagcgg ccccacttct
     2161 accgttttgc cgtagaaagt cggtgatttc acccaggaat atttcccgtc gtcagaccaa
     2221 ccatcataag ccggaatggt ggtaccttcc cacggcgcct gtggcgcttc gtctttatac
     2281 caggagtgct tcgcgctttc ctgaatgcct ttgatcaggt attcatcgga atgagaagtg
     2341 atcggacgat acgaggacag atccgcattc tcaatgtagc cgcccgggaa caggaagctg
     2401 ccgtttttgc tgtcggtcgg gaattccggc acgctcaggt agttcaccgc acctttaccg
     2461 cgcgtcagcc attccgggta gaacgcggcg ataaccgcgg tatcaacctt ataaacctgc
     2521 tcaacaaagt cgctcagttt gtcgatgaaa gacttgatgt acatcaggcg ctcaaggttc
     2581 aacacgccca acccgtcgag gttgattggg ttcgcgacac cacccactgc caggttctga
     2641 atgtgcggcg ttttaccgcc cagcagcgcc acgacgcggt tagcgtcacg ctggcactcc
     2701 agcgcctgca ggtagtgcgc taccgcaatc aggttcactt ccggcggcag tttcatcgcc
     2761 gggtgacccc agtagccatt agcgaaaata cccaactgac cgctggcaac cagatctttg
     2821 atcttgttct gaactttagt gaactcttcc ggactgttca gatgccaggt cgaaacgcct
     2881 ttcagcattt cggaggcttt ggttgggtca gcttgcagtg cagaagtgat gtccacccag
     2941 tccagcgccg aaagctgata gaaatgaacg atatggtcat gcgtggtgtg cgcagccaga
     3001 atgatgttac ggatgtattg cgcgttaacc ggaacgtcga tattcagcgc actttctgcc
     3061 gcacgaacgg aagacagcgc gtgagtggta gtacatacgc cacagatacg ttgcacaatc
     3121 atccatgcat cgcgcggatc gcggtttttc acgatctctt ccatgccgcg ccacatggta
     3181 ccggaagccc atgctttcga aacgacgcca ttttcgattt cgcaatcgat gcgtaaatgc
     3241 ccctcaatac gggttaccgg atcaatagta attctctggc tcatgctttg ctcgcctcat
     3301 gacgattatg atcgttttgt tttaaaggag gaagtatcgg cagtagacga atgagtacga
     3361 tgtaagcgca aatctcaata gccacaaaac caatagaaat caacagttct tcccaggtcg
     3421 ggaagtaggc gtaaccgccg cccgggttga atgccaccag cgaataggtc agacgccagg
     3481 ttgcacaacc taacagtgcg ctcagtgctg acaggaacag catgcgggaa tcattacgca
     3541 gcttcgccac acgcagaacg accagcggga agagcatcag caggacttca atccagaaca
     3601 tcacggagta gaagtcaccg gcaaacgcta acgacagctt gtcgcgatag ataagctcgc
     3661 caaagcgcag cacgatgaaa atcgccagca acacactgat ggtgttggtc agcttaacaa
     3721 acagactctt ttcatccgga ccgttgccac gcagacccgc ctgcaccagc gaaccttcaa
     3781 agatgacaat cgagaagccc atgatgaacg ccgtcagcag cgagaacagc ggcaacattt
     3841 catagctctg ccacaacgga tgcaccttgt agcccgccga gatcatcagc gaccccattg
     3901 aagactggtg catggtcggc agcagcgcac cgagcgcgat gatgaagaac atcaccttgt
     3961 ttagtcgctg tagcgacacc ttccacccca gacgttcaaa cagtgccgga gcaaactcca
     4021 gtgccatcac gccgatatag atggtcatac agaccgccgt ctcgaacagt accgagttca
     4081 cgttgaagtg acccggaatg tagaagtacg gcaggttcca gtagcgaccc acgtcgatag
     4141 tgatcgacaa gccacccagt gagtaaccaa acagactcgc caacagcgcc ggacgcacca
     4201 gcggatggta ttgcccacgg ttaaagacgt ataccgccca cgccagcgcc cagccgccac
     4261 aggcaaagcc ggtgccaatc agcaggtcaa acgcgatcca cacgccccac gggaagccgc
     4321 cgttcaggtc agagacagag cccagaccga acaccagacg cttcacaatc aggagcatac
     4381 agatgacgat taacggtcca aaaatcatga ccggtttact gatgattttg ccgcccagcg
     4441 gttgtggatc atgactcatg atcgtctcct ccgtcgtgat ggtcgttttt ggtgttgcga
     4501 cgaaccagca cggttaagcc cgccagcaca gccagtggta gcatcatgcc tttatacagg
     4561 gtgtgttgaa tattttcgga acgcgcaccg gtagaaagat cgtccagttt cggcaggtcg
     4621 agattttcat aaggcacacc cgtcagtacc agaacctgag taccgccgcc ctctttctcg
     4681 ccgtacagat gcggataata tttcggcacc gtatgcaggt aagtgtcgcc agatttcagc
     4741 gtctgacgcg gatagtggta ttcgctgcca ggcttcagcg ccagacgttt tttcgcctcc
     4801 gccatcagct cttcacgcgt accaaaaatt accgcgcccg ccgggcacac ttctacgcag
     4861 ccaggcaaac cgcctttatc gagacgttcc acacctttct ggttgcacaa ctcgcactta
     4921 tgcagcgcac caaacgggtt gttgtagtcg tacttcggca cgttgtatgg gcaggcgacc
     4981 atgcagtaac ggcaaccggt gcacacatct ttgtcgtaat ggacaatgcc ggttttcgga
     5041 tcttttttca gcgcagagac cgggcacaca gagacacagt tcggatcgac gcagtgcata
     5101 cactgtttct taatgtacgc gtagccgttc tcctcctggt ctttgttgac ccctgtgccg
     5161 ctggtccaca cctgaatgat gttattggta tacggcgaca gtttgtcgtt gttcgaccag
     5221 gtctgttccc cttgcgggtt acgttcaggg aagttgatat cctgacactt ggtgacgcaa
     5281 gcctggcagc ctacgcacaa ggtcgagtcg tacaacatcc ccagcgatcc cggaattggc
     5341 gggcggtttt cagcagccgc atgactgaca gacggcagcg cgcccgtcag caatgccccg
     5401 caggaggctg ctttaataaa attacgtctg ttcacggtta ttctccccgt gagtcagcgt
     5461 tatctttctt ttgctgacga cccagttcac gcaccgccat cacgctgaca ccggcaacca
     5521 gcccaaccac accgccgagc aaaccaatag cgcctgcaga gacgttgccg ccctctttag
     5581 cgttaacatc cggtttctgt gaacgcggag tctgattttc gacgttggca agctgatgga
     5641 tgcctttatg gaagccgata ccttcttcgt tacagccata gcatgggtga ccaatcgcta
     5701 ccggccacac gccgccaaca tcgcagaatt gcagcgttga gcagttgccg taagtttctg
     5761 gccctttaca gccgaggtgg tacaggcacc agccttcacg gtggccttca tcaccgaact
     5821 ctttggcaaa acgaccagca tcgaagtgcg ggcgacgttc gcagtgttcg tgaatcagac
     5881 ggccataggc gaaggtcgga cgatttttgt catccagttt cggcggtttg ccgtaagtga
     5941 tgatgtgcgc aacggtcgcg aggaagttgt gcgggttcgg cgggcagccc ggaatattga
     6001 taacggtttt gcctggcaga acttcttgca ggctgactgc gccagttggg ttaactccag
     6061 ctgcggcaac accgccccac gcagagcagg aaccgatagc gataatcgct gctgcgcctt
     6121 ctgccgcttt gcggatgtga tccacaatcg gctcaccagc aaccatgcaa taaataccgt
     6181 tatcttttaa tgggatggaa ccatccacaa ccaacacata ctgccctttg tacttctcaa
     6241 gtgcgttatg tttgttctct tcgacctgat gaccgaaggc ggcggaaagc acttcgtgat
     6301 actccagaga gatagtctcc agcacgaggt tttctaccgt tggatgcgtt gcacgaagca
     6361 gagattccgt acaaccggtg cactcctgcg cgccaatcca gataactggc ggacgctgcg
     6421 ggttagtaac cgattcggcc atctctgcag cggctttgct acttaacccc atggtggcgg
     6481 ctaatgctgc acaaagcttc atgaaatcac gacggttaat gccgtgagaa tggatgaggg
     6541 tgttatctcc agtcatttat agttattccg ttgcgaagac ctggcatata ttttgcctca
     6601 atcgcaaaat caataatgcg atcgatgcgc catttaccac acatttatta tggttatcga
     6661 tatcatgata ctgcggcggg gcgctaaaac gaagggaaga agcattagtg taattaatta
     6721 aagcaagata atacgtatgt ttgatcaatt ttcgaggcga taaccggcca taaaaaagcg
     6781 caacgtagaa caggaattat tctcacgaaa gaaatccatt accatctctt tatccagtcc
     6841 atagcggcgc gtcagaatac ccgcttccca ggcgctaagc tggcgatctc cggtcttttc
     6901 gtacatccgg tgtgagtagc ctaatacaaa accgcgttta taatcggcac agaattttgt
     6961 cacattaacc gcactgtcgg catgcgttgc ttttaatccc gccattaagc ctttaccaaa
     7021 atggttattc atcgttcacc tcattcgtta tatatcgcca tatatagcga tattttaggc
     7081 aaagaacgac ttttgcgcac gctatttttt catgcttgtt taagacgtaa tccagtaaga
     7141 gataaaccta tcaggagaga tatttatcga accatttcag tgtcctttgc caggcaagat
     7201 cggcggcaga tttgtcataa cggggcgtgg aatcattatg gaatccgtga ttaacccccg
     7261 gatagatata cgcctcataa accttattat tggctttcaa cgccgcctcg taagcaggcc
     7321 agccctcgtt gattcgggtg tccagttccg cgaagtggag tagtaaaggc gcttcaatct
     7381 tcgccacatc ggcagtgggt gcctgacgac cataaaacgg caccgcgcag gccagttccg
     7441 gatacgcgac agccgccgcg ttcgatacgc caccgccata gcaaaatccg gtaataccca
     7501 ctttgcctgc cgcttgcgga tagcgttgca taaactcaat tgcggcaaag aaatcattca
     7561 tcagtttggt tggatcaacc tgctgttgca gctcacgacc tttatcatca tttcccggat
     7621 aacctccaac ggaacttaag ccgtcaggtg ccagggcgat ataccccgcc ttcgccactc
     7681 gccgtgccac atcttcgata tacggattca gtccacgatt ctcatgcacc actaccacgg
     7741 ctggcgtttt gccgctcatt tttgcgggtt tcaccagata accccgtacc tcgccgtgac
     7801 catttggcga aggatacgtg atgtactcag caacaatctc cgggtcggta aactctacct
     7861 gagtcgccag cgcataattt ggcttgagca aatcaaacaa cgctaatgcc gtcatcccgc
     7921 ccaccgcata cttcgccgca aggttgagga actcacgttt cgagattttc ccgtgagcgt
     7981 aatagtcgta gtaatccaac aactcttgtg ggaaatcttt ggcggttaaa cgcggcatcg
     8041 ttgcactcct caactggtgt ttttttaagc aaagcataag cacgtgtttt tgcccagttt
     8101 ttcgtcactc tgtgagccag actacgggat acgcgctggc gaatcgctaa actagaaaca
     8161 ttgtttcgaa attgaacggt ggaaaggaga ggtcatggtc tggttagcga atcccgaacg
     8221 ttacgggcag atgcaatacc gctattgcgg aaaaagcggt ttacgcctgc ccgcgttatc
     8281 gctcggttta tggcacaatt tcggtcacgt taacgcgctg gaatcacagc gtgcgatcct
     8341 gcgtaaagcg tttgatttgg gcattacgca ctttgattta gccaacaatt acgggccgcc
     8401 tccaggaagc gcagaagaga actttggtcg cctgctgcgg gaggattttg ccgcttatcg
     8461 cgatgaactg attatctcta ccaaggctgg ctacgatatg tggcccggcc cttacggctc
     8521 tggcggttca cgtaaatacc tgctcgccag cctcgaccaa agcctgaagc gtatggggct
     8581 tgagtatgtc gatatctttt actctcatcg cgtcgatgaa aatacgccga tggaagaaac
     8641 cgcctctgcg ctggctcatg cggtacaaag cggtaaggcg ctgtatgtcg ggatctcctc
     8701 ttactcgcca gagcggacgc aaaaaatggt cgagttgctg cacgagtgga aaattccgct
     8761 tttaattcat caaccttcgt acaatttact gaaccgctgg gtggataaaa gcggcctgct
     8821 ggataccctg caaaataacg gcgtgggctg tattgccttt actcctctgg ctcagggatt
     8881 gctgaccgga aaatatctca acggcattcc gcaagattca cggatgtatc gtgaagggaa
     8941 taaagttcgt ggtctgacac cgaaaatgct taccgaagcc aacctcaaca gcctgcgctt
     9001 attgaatgaa atggcacagc agcgtggaca atcaatggcg caaatggcgt taagttggtt
     9061 gctgaaagat gagcgagtga cgtcggtatt gattggtgcc agccgcgcgg agcaacttga
     9121 ggagaacgtg caggcgctga ataatctgac atttagcacc gaggagctgg cgcagattga
     9181 tcagcatatc gccgatggcg agctgaatct gtggcaggcg tcgtccgata aatgacctgt
     9241 taataacggg cgcgcgaacc gcgcccgaat cagatcagtg attatgacga gtcagtcggt
     9301 caagatagcc catcacaaat gcagaaagca caaacgtcag atggataatg acgtaccaca
     9361 tcagtttgtt atccgggaca tttttcgcat ccataaagac gcgcagtagg tgaatggaag
     9421 aaattgccac aatcgacgct gctactttgt ttttcagcga cgttgcgtcc attttcccca
     9481 gccagttcag cttctctttg ttctcggaga tatccagctg tgagacgaaa ttctcataac
     9541 cggaaaacat caccatcacc agcaaaccgc caaccagcgt catatccacc agcgacagca
     9601 acacgaggat caaatctgat tccgccatcg agaagatatt cggcagtacg tgaataatct
     9661 cctggaagaa cttcagcgcc agggcaacta acgccagcga aaggccaaag tacacggggg
     9721 caagcagcca gcgagaagca tacattgcat tttcaagaaa acgttccata cattcctgtc
     9781 gtgtagttaa aacgggcaac agtatatcgc aattgagtaa acagcacgca acagcaaatc
     9841 aacatatacg ttaaaccttt gtcgcataat tctgaggttt agggatcttc ctggttccct
     9901 tatcaacgca tcgagagcgt ctacccttaa aggacgttga acctgaaggg agaaaaacga
     9961 tgtctcattt aaaagacccg accacgcagt attacactgg tgaatatccc aaacagaaac
    10021 aaccgacgcc aggcatccag gcgaagatga caccggtacc ggattgcggc gagaaaacct
    10081 atgttggtag cggtcgcctg aaagatcgta aagcactggt gacagggggc gattccggaa
    10141 taggtcgcgc tgccgccatc gcttacgcgc gtgaaggggc tgacgtggcg atcagttatc
    10201 ttcccgtgga agaagaagac gctcaggatg tgaaaaagat cattgaagaa tgcggacgca
    10261 aagccgttct gctgccaggc gatttaagcg atgagaaatt cgcccgttcg ctggttcacg
    10321 aagcgcataa ggcgttaggc gggctggata ttatggcgct ggtcgccggg aaacaggttg
    10381 ccattccgga tattgcagac ctcaccagcg aacagtttca aaagaccttt gccattaacg
    10441 ttttcgcgct gttctggcta acccaggaag cgatccccct gctaccgaaa ggtgcaagta
    10501 tcatcaccac ttcgtcaatc caggcatacc agccaagtcc gcatttactg gactatgcgg
    10561 ctacgaaggc ggcgattctg aactacagcc gtggcctggc aaaacaggtc gcggagaaag
    10621 gtattcgggt gaatattgtc gcgccaggcc cgatctggac agcactgcaa atttccggcg
    10681 gacaaacgca ggataagatc ccgcagtttg gtcagcaaac gccgatgaag cgtgcggggc
    10741 aaccggcgga actggcccct gtatatgttt atctggcaag tcaggagtcg agctacgtca
    10801 ccgcagaagt gcacggtgtg tgcggcggcg agcatttagg ttaaaaaaat gcccggttgt
    10861 gaaaagcaac cgggcatcat tgtgaattca ctcttacctg atgtggcgaa aacgccttat
    10921 ccgcctacaa acgcatgaag attcaacatg ttgcaataga ttttgtaggc ctgataagcg
    10981 tagcgcatca ggcattgagc acctaatgcc ggatgcgtcg tgaacgcctt atccggccta
    11041 caaacgcacg aagattcaac ctgttgcaat agattttgta ggcctgatga gcgtagcgca
    11101 tcaggcaatt ctactttact tcgctttggc ggtttcttcg ccgaccagac ctatcttcag
    11161 gtaacccgcc tgatgcagcg tatccattac cttcatcaac gtctcgtaat cgacggtttt
    11221 gtccgctcgg aagaagatgg tggtgtcttt cttgccttcg gttaacgcat tcaacgccgt
    11281 aatcattgtt tcatcggtga ccggatcgtt accgataaac atcgagttgt ctgccttcac
    11341 cgacagataa accggttttt ccgggcgcgg ctgcggcgtg ctggtagaag caggcaagtt
    11401 caccttcaca tctaccgtcg ctaacggtgc cgccaccata aagataatca gcagaaccaa
    11461 catcacgtcg ataaacggcg tcacgttgat atcatgcatt tcgccgttat cgtcgaggtt
    11521 ttcgttaaga tgcattgcca tcggatatta tcctgcgcgt aatttttgtg cgacacgaac
    11581 cggatgcgca gcggcgctgg cttccagatc caggtcacgg ctttgcagca acaatacctg
    11641 cgctgcaaca tcacccagca tcgctttaaa gccgccaatc tggcgtgcaa atacgttata
    11701 gataacgacc gcaggaatcg ctgccacgag gccgattgcc gttgctaaca gagcttctgc
    11761 gatacccggc gcaacgactg ccaggttagt ggtctgcgtt tgcgcgatac caataaagct
    11821 gttcatgatg ccccagaccg taccaaacag accaacgaac ggagaaatcg cgccgatggt
    11881 tgccagatag ccgttaccgc ggcccatttg acgacccact gcggcgaccc gacgctccag
    11941 acggaagctg gtacgttctt taataccttc gttatcgtcg ctgccttctg acagttccag
    12001 ctcattctgc gcttcattga gcaaatgcag gcttaagctt ttgctaccaa aatcagcggc
    12061 gatatcgttg gcctggttta aggaacgcgc ttcagccagc agttgctgct cgcgcttaag
    12121 gcgacgcttc tgattgaaga actctacgct cttactgaag aagattgccc aagtgactac
    12181 ggaggccaaa ataagcccaa tcatcacgca cttaacgaca atatcggcgt gctgatacat
    12241 accccagacg gaaaggtccg tctgcattaa attattaccc actgtgtatc tccaggacgc
    12301 aagtcacaaa atctgcgcat aataatatca aaatgacgtc gaattgatag tcgttctcat
    12361 tactatttgc atactgccgt acctttgctt tcttttcctt gcgtttacgc agtaaaaaag
    12421 tcaccagcac gccatttgcg aaaattttct gctttatgcc aattcttcag gatgcgcccg
    12481 cgaatattca tgctagttta gacatccaga cgtataaaaa caggaatccc gacatggcgg
    12541 acaaaaagct tgatactcaa ctggtgaatg caggacgcag caaaaaatac actctcggcg
    12601 cggtaaatag cgtgattcag cgcgcttctt cgctggtctt tgacagtgtg gaagccaaaa
    12661 agcacgcgac gcgcaatcgc gccaatggcg agttgttcta tggacggcgc ggaacgttaa
    12721 cccatttctc cttacaacaa gcgatgtgtg aactggaagg tggcgcaggc tgcgcgctat
    12781 ttccctgcgg ggcggcagcg gttgctaatt ccattcttgc ttttgtcgaa cagggcgatc
    12841 atgtgttgat gaccaacacc gcctatgaac cgagtcagga tttctgtagc aaaatcctca
    12901 gcaaactggg cgtaacgaca tcgtggtttg atccgctgat tggtgccgat atcgttaagc
    12961 atctgcagcc aaacactaaa atcgtgtttc tggaatcgcc aggctccatc accatggaag
    13021 tccacgacgt tccggcgatt gttgccgccg tgcgcagtgt ggtcccggat gccatcatta
    13081 tgatcgacaa cacctgggca gccggtgtgc tgtttaaggc gctggatttt ggcatcgatg
    13141 tttccattca ggccgctacc aaatatctgg ttgggcattc agatgcgatg attggcactg
    13201 ccgtgtgcaa tgcccgttgc tgggagcagc tgcgggagaa tgcctatctg atgggccaga
    13261 tggtcgatgc cgataccgcc tatataacca gccgtggcct gcgcacatta ggtgtgcgtt
    13321 tgcgtcaaca tcatgaaagc agtctgaaag tggctgaatg gctggcagaa catccgcaag
    13381 ttgcgcgagt taaccaccct gctctgcctg gcagtaaagg ccacgaattc tggaaacgag
    13441 actttacagg cagcagcggg ctattttcct ttgtgcttaa gaaaaaactc agtaatgaag
    13501 agctggcgaa ctatctggat agcttcagtt tattcagcat ggcctactcg tggggcgggt
    13561 atgaatcgtt gatcctggca aatcaaccag aacatatcgc cgccattcgc ccacaaggcg
    13621 agatcgattt tagcgggacc ttgattcgcc tgcatattgg tctggaagat gtcgacgatc
    13681 tgattgccga tctggacgcc ggttttgcgc ggattgtata acattgccac ttttggacaa
    13741 ttttgcagac attttattgt gaaaagtctt aaattgttgc gtccgggatc aaggcgtccc
    13801 ggacgattca ggagtacaat aggcaaataa aggcttaaac gctgttccac aggaaagtcc
    13861 atggctgtta ttcaagatat catcgctgcg ctctggcaac acgactttgc cgcgctggcg
    13921 gatcctcata ttgttagcgt tgtttacttt gtcatgtttg ccacgctgtt tttagaaaac
    13981 ggcctgctgc ccgcctcatt tttgccaggc gacagcttgt tgatactggc aggcgcattg
    14041 attgcccagg gggttatgga ttttctgcct acgattgcga ttctgaccgc cgcagcaagt
    14101 ctgggctgct ggctaagtta tattcagggg cgctggttag ggaataccaa aacggtgaaa
    14161 ggctggctgg cacagcttcc tgctaaatat caccagcgcg ccacctgcat gtttgaccgc
    14221 cacggtctgc tggcgctgct ggctggacgt tttcttgcat ttgtccgtac gctgctgcca
    14281 accatggcgg gaatttccgg tctgccaaac cgccgtttcc agtttttcaa ctggttaagc
    14341 ggattgctgt gggtcagcgt ggtaaccagt ttcggctatg ccttaagtat gattccgttc
    14401 gttaaacgcc atgaagatca ggtaatgacg ttcctgatga tcctgccaat tgccttgtta
    14461 accgctggct tgttaggcac gctgtttgtg gtgattaaaa aaaaatactg taacgcctga
    14521 cgattttccc tgttcccggt tgctgtaccg ggaacgtatt taattcccct gcatcgcccg
    14581 cattcttgcc gcatcttccc ccggcgtcac accgaagtaa cgtttaaact cacggctaaa
    14641 ttgcgatgcg ctttcatagc cgacgcgcat cgctgctgcg ctggccttca tgccgtcatg
    14701 gatgatcatc atccgcgcct tatgcagacg gtaattcttc aaatactgca acggcgaggt
    14761 actggtgaca gacttaaaat tatggtggaa cgccgatacg ctcatgttgg cttctgccgc
    14821 cagttgctcg acgctcaggt tttcggtgta tttattctca atccgtttca gcacgcggct
    14881 aatcagactg aagtgagtct ggcgactgac cagcgccagt aacgcgccgc cgcaaggtcc
    14941 ggtcagcacg tagtacagaa tttcgcggat gatctgtttg ccgagaatac gcgcatccag
    15001 tggtcgctcc atcacgtcga gtaaccgctc cgccgcgcat aaaatctctt ctgataacgt
    15061 ggcggagtta atcccgctgg ctgccatcga cggctggaaa tgctcatctt cgccaatgtc
    15121 catcaacagt tcctgtaact gcaaaatatc gacattgaga cgcaaccctg ccagcggcac
    15181 ctctgacgtg gcataggttt cgcactcaaa cggcaacggc accgtcagca gcaggtattc
    15241 attggcatca taacgaaaca cgcgttcatt gatataaccg attttatgcc cggaaaagag
    15301 aattatgatg ccaggctcgt acatcaccgg tgtacgtgcg aaaggcgtct cgccatacaa
    15361 caaacgcaca tcgggcaaca gttctgacaa actattttct ttatttttca gtttattaac
    15421 tttatccgcc agcaagcggc aaatctcttc acgtttcata tcgcgtaatt tcttaggaat
    15481 aatgcggcaa tttgattgtg cgcaattttg tagcatttct ccagcactct ggagaaatag
    15541 gcaagacatt ggcagaaatg agcattgaga gccagggcgc tggcgatcac aatgaaaaac
    15601 atcaggcaga tcgttctctg ccctcatatt ggcccagcaa agggagcaag taatgaacaa
    15661 ctttaatctg cacaccccaa cccgcattct gtttggtaaa ggcgcaatcg ctggtttacg
    15721 cgaacaaatt cctcacgatg ctcgcgtatt gattacctac ggtggcggca gcgtgaaaaa
    15781 aaccggcgtt ctcgatcaag ttctggatgc cctgaaaggc atggacgtgc tggaatttgg
    15841 cggtattgag ccaaacccgg cttatgaaac gctgatgaac gccgtgaaac tggttcgcga
    15901 acagaaagtg actttcctgc tggcggttgg cggcggttct gtactggacg gcaccaaatt
    15961 tatcgccgca gcggctaact atccggaaaa tatcgatccg tggcacattc tgcaaacggg
    16021 cggtaaagag attaaaagcg ccatcccgat gggctgtgtg ctgacgctgc cagcaaccgg
    16081 ttcagaatcc aacgcaggcg cggtgatctc ccgtaaaacc acaggcgaca agcaggcgtt
    16141 ccattctgcc catgttcagc cggtatttgc cgtgctcgat ccggtttata cctacaccct
    16201 gccgccgcgt caggtggcta acggcgtagt ggacgccttt gtacacaccg tggaacagta
    16261 tgttaccaaa ccggttgatg ccaaaattca ggaccgtttc gcagaaggca ttttgctgac
    16321 gctgatcgaa gatggtccga aagccctgaa agagccagaa aactacgatg tgcgcgccaa
    16381 cgtcatgtgg ggggcgacgc aggcgctgaa cggtttgatt ggcgctggcg taccgcagga
    16441 ctgggcaacg catatgctgg gccacgaact gactgcgatg cacggtctgg atcacgcgca
    16501 aacactggct atcgtcctgc ctgcactgtg gaatgaaaaa cgcgagacca agcgcgctaa
    16561 gctgctgcaa tatgctgaac gcgtctggaa catcactgaa ggttccgatg atgagcgtat
    16621 tgacgccgcg attgccgcaa cccgcaattt ctttgagcaa ttaggcgtgc cgacccacct
    16681 ctccgactac ggtctggacg gcagctccat cccggctttg ctgaaaaaac tggaagagca
    16741 cggcatgacc caactgggcg aaaatcatga cattacgttg gatgtcagcc gccgtatata
    16801 cgaagccgcc cgctaagctt tttacgcctc aaactttcgt tttcgggcat ttcgtccaga
    16861 cttaagttca caacacctca ccggagcctg ctccggtgag ttcatataaa ggaggaacgt
    16921 atggctaatc caaccgttat taagctacag gatggcaatg tcatgcccca gctgggactg
    16981 ggcgtctggc aagcaagtaa tgaggaagta atcaccgcca ttcaaaaagc gttagaagtg
    17041 ggttatcgct cgattgatac cgccgcggcc tacaagaacg aagaaggtgt cggcaaagcc
    17101 ctgaaaaatg cctcagtcaa cagagaagaa ctgttcatca ccactaagct gtggaacgac
    17161 gaccacaagc gcccccgcga agccctgctc gacagcctga aaaaactcca gcttgattat
    17221 atcgacctct acttaatgca ctggcccgtt cccgctatcg accattatgt cgaagcatgg
    17281 aaaggcatga tcgaattgca aaaagaggga ttaatcaaaa gcatcggcgt gtgcaacttc
    17341 cagatccatc acctgcaacg cctgattgat gaaactggcg tgacgcctgt gataaaccag
    17401 atcgaacttc atccgctgat gcaacaacgc cagctacacg cctggaacgc gacacacaaa
    17461 atccagaccg aatcctggag cccattagcg caaggaggga aaggcgtttt cgatcagaaa
    17521 gtcattcgcg atctggcaga taaatacggc aaaaccccgg cgcagattgt tatccgctgg
    17581 catctggata gcggcctggt ggtgatcccg aaatcggtca caccttcacg tattgccgaa
    17641 aactttgatg tctgggattt ccgtctcgac aaagacgaac tcggcgaaat tgcaaaactc
    17701 gatcagggca agcgtctcgg tcccgatcct gaccagttcg gcggctaaca tgcaaattct
    17761 cccggtggcg gtaatgttcc gctaccggac ttttcagaaa tcatttattc ccctcgcgtc
    17821 ccgcccgttg ttactcttcc ttgttcagga atgccaaata taaggacatc atcatgcaga
    17881 gccggaagct cttaaaagaa caactcatct atatccggga taaacgcaac ggagaggtga
    17941 aaaacagatg aaaataatac ttctgttttt agcagccctg gcaagtttta ccgtacacgc
    18001 acagcccccc tcactgaccg tagaacaaac agtccggcat atttatcaga actataaatc
    18061 agatgccact gccccttatt ttggtgaaac cggagagcgg gcgataactt ctgcgcgtat
    18121 tcaacaggcg cttaccctga acgacaatct tacgctgccg ggcaatattg gctggctgga
    18181 ttatgatccg gtttgtgatt gtcaggattt tggcgatctg gtgctagaaa gcgttgcgat
    18241 aacccaaact gacgccgatc atgccgatgc cgttgtgcgc tttcgtatct ttaaagatga
    18301 taaagaaaag accacgcaga cactgaaaat ggtggcggaa aatggtcgtt gggtcattga
    18361 cgatattgtc agcaatcatg gcagcgtctt acaagcagtt aatagcgaga atgaaaaaac
    18421 gctggccgct ttagcttcgt tgcaaaaaga acagccggaa gcctttgttg ccgaactctt
    18481 tgaacatatt gctgattata gctggccgtg gacgtgggtg gtttccgact cttaccgcca
    18541 ggcggttaat gccttctata aaaccacctt caagacggcc aataatcccg atgaagatat
    18601 gcaaatagaa cggcaattta tttacgacaa tccgatctgt tttggcgaag agtcgctatt
    18661 ttcacgcgtt gatgaaattc gagtcctgga gaaaaccgcc gattccgccc gcattcatgt
    18721 tcgttttacg ctgaccaatg gcaacaacga agagcaagaa ctggttttac agcggcgcga
    18781 aggcaagtgg gaaatcgctg attttatccg cccgaacagc ggcagcctac ttaagcagat
    18841 tgaggcaaaa accgccgcca gattaaagca atgagctgaa ttaaataaca attagccgga
    18901 acaataaata aaagggaaca ctatatgaaa acgattttca ccgtgggagc tgttgttctg
    18961 gcaacctgct tgctcagtgg ctgcgtcaat gagcaaaagg tcaatcagct ggcgagcaat
    19021 gtgcaaacat taaatgccaa aatcgcccgg cttgagcagg atatgaaagc actacgccca
    19081 caaatctatg ctgccaaatc cgaagctaac agagccaata cgcgtcttga tgctcaggac
    19141 tattttgatt gcctgcgctg cttgcgtatg tacgcagaat gataaaaaaa tccccggcag
    19201 catgtcagtt gccggggatt ttttttaacg tccaaccgcc gctttagggc gtttcttcgc
    19261 accagcattc accggacgag attgcgtaga cgacgctttt tttgccgtag caggcgtctg
    19321 acgctgggtc gccatcggcg tatgtttcgt caacgccgga cgggtattgc ggttctggcg
    19381 acgagcttca cgcatctctt caatggttgg cgcaggcact aagcaatcgc gacggctgcc
    19441 aatcagatgc tttttgccca tcgcttccag cgcctggcgg attaacggcc agtttgccgg
    19501 atcgtggtaa cgcaacaacg ctttatgcaa acgacgctgt ttgtcgccct tcggtacgaa
    19561 gacgtcttcg ctcttataac caatcttcgc cagcgggttt ttcccggtgt aatacatggt
    19621 ggttgagttc gccagcggcg atgggtagaa gttctgtacc tggtcgagac ggaaacgatg
    19681 ctttttcagc cacagcgcca gattcaccat atcttcatca cgcgtaccgg ggtgcgcgga
    19741 gatgaaatag gggatcagat actgctcttt acctgcctgt tttgagtaag tatcgaacag
    19801 ctctttaaag cggtcatagc tgcccatgcc cggcttcatc atcttcgata acggcccttc
    19861 ttcggtatgt tccggggcaa tcttcagata accgccgacg tgatgggtcg ccaactcttt
    19921 gatatagcgc ggatcttcca cggcgatgtc ataacgtacg cctgaggcga tgaggatttt
    19981 tttaatgcct ttcagatcac gcgcacggcg atagaggttg atcgtcggtt cgtggttagt
    20041 gtccatgtgc ggacaaatat ccggataaac gcacgacaaa cggcgacaag tttgttcagc
    20101 gcgtggcgat ttgcagcgca acatatacat gttggcagtt ggcccaccga gatcggaaat
    20161 cacgcccgta aaacctggaa cggtgtcgcg gatcgcttcg atctcattaa tgatcgaatc
    20221 ttccgaacgg ctctgaataa tgcgcccttc gtgctcggta atagaacaga aagaacagcc
    20281 gccaaagcag ccgcgcataa tgttgaccga aaaacggatc atttcgtaag ccggaatacg
    20341 ggcattgcca taggccggat gtggcacgcg cttgtacggc agcgcaaaaa cgctgtccat
    20401 ctcttcggta gaaagcggga tagcaggcgg gttgatccac acatagcggt caccgtgttt
    20461 ttgcatcaat gcgcgggcgc agcctgggtt ggtttcgtgg tgcagaatgc gcgaagcatg
    20521 ggcgtacagc actttatcgc ccttcacttt ctcgaaagaa ggcagcaaca cgtaggtttt
    20581 ttcccacggt ttcgggcgcg gtggctgcac ggttacggct ttggcttcct gctttttcgg
    20641 tgccaccggt ttgttatccg cgcacggcaa atcttcacca tacggatgcg ggattgggtc
    20701 gatttttcca ggggtatcaa gacgggtgga atccacgccg ctccagccag gcagcgcctc
    20761 tttcacgata atcgcggtat tacgcacatc gcggatttca ctaatcggct cgcccatcgc
    20821 cagacggtgc gccacctcca ccagcggacg ctcaccgtta ccaaacatca gcatgtcggc
    20881 tttcgaatcc accagcacgg aacggcgcac ggtatcggac cagtaatcat aatgtgcggt
    20941 acggcgcaga ctagcctcaa taccgccgag gatcaccggt acatctttcc acgcctcttt
    21001 acaacgctgg gtataaacca gtgtggcgcg atccgggcgc ttacccgcga cgttatccgg
    21061 cgtgtaggca tcgtcatgac gtaaacggcg atcggcggta taacggttga tcatcgaatc
    21121 catgttgcca gcagtaacac cgaaaaacag attcggttta cccagacgca tgaaatcgtc
    21181 tttgctgctc cagtctggct gggcgatgat cccgacgcga aagccctgtg cttccagcat
    21241 acgaccgcaa atcgccatcc cgaagcttgg gtgatcgaca tacgcgtcgc cagtaaccaa
    21301 aatgatgtcg cagctatccc agccaagttg atccatctct tcacgagaca tcggcaaaaa
    21361 cggtgccggt ccaaaacagg cggcccagta ctgcggccag gagaacaggt cgcgatccgg
    21421 ttggatcagg gagatagagc tcattttgct tccagaaatg ataaaaaaat aatcaaaggc
    21481 cggggattat aagccggaac gaaagagaaa tcgaaaggta ttccatactc gccctcctcg
    21541 ggcgagtatg aagattacgg taccggattg accaaaagtt gccctatcga gccacggtcc
    21601 gccatttcca gcgtctgact gttgaagtag aacgggaagt gcgcccagga aggctgaccg
    21661 aaataaacaa gcagctccac ttgtccgtca acccaaacgg tatctttcca gcctctgtct
    21721 tccgggaacg gcatcgcgcc attcacgtta cggatctgga acattacgcc ttcaatatgg
    21781 aacgcttgcg gctcgtccgc gcgtaccgtc cagcgttccc acgttccttg ctgcgcggtg
    21841 acatcaatac ggttgacgtc ccacagctgt ccattaatac ccgggtcatc acccagactg
    21901 atatcgcgac tgcgaattgg cgaaccagcc atgatttcag ttggcagcaa gcgcatcgga
    21961 agactgtctg tgaccagcgg cagaaggccg gttgggcgca gcgttagcac cagggtagaa
    22021 accagaatac tggatggctc aaagaagccg cgaatacgat caacaatgct cgccgcttcg
    22081 ccacaggtga tcgacacttc atcgccgttg ctcatatcca ccagaatctc gcggcgctcg
    22141 cccggtgcca gcgaaagttg cttcaccgat acaggagcag gcaggaatcc ctgatcgcca
    22201 gaaatcacat gtaacgggcg accatcgctc atctgtagtt gatagcgacg agagttcgac
    22261 gcgttcagca gtcgcaagcg cacccagcca cgcgagactt caacgtacgg gctttgtaca
    22321 ccgttaacca gcagcgtatc accaacaaag ccgccgcttc ccggttcgtt gtattctggc
    22381 gtaccaaagt tatccagccg tttatcctgg ataatgaccg gaaaatcatc cacaccataa
    22441 tggttgggga taggcagcga cttgctgact tcatcttcca ccagccacat tccggcaagg
    22501 ccgttataga cctgctgagc cgtgcggttg ggagtattgg cgtgatacca cagagtagct
    22561 gcgttctggc gaatgggcag tacgggtgcc cagtcagcgt ttggcgacat catccgtgcc
    22621 ggaccgccca tcagcgggcc tggtacctgt agcccggcca ccgtcattga gacattttct
    22681 gtcaggcggt tgctgtaaat aagcttaaca tcgtcgccct tccagacgcg gatagtcggc
    22741 cccaggtaac gaccattgat tccccagacc gacgcgcgtg tccctggcgt aaatgaccag
    22801 tgcgcacgtt gtacagtcat aaacagcggt tgcccacggc gagattcaag tagcggcgga
    22861 acgggtagcg gttgctgttg cccggctgcg ctggccttca ggggaacagc gcctgcacaa
    22921 agtgcaatcc ccgatgcctg aatgaactga cgccgactga gtgacatatt tgctccatgt
    22981 aaaactggct aaagtaatac cgtgcaggaa agtgttcccc gcaaaaatac agattgccga
    23041 cttaaacttt tccggcggct tcgcgttctg cgacttcttt atcgagctcg gcgatttttt
    23101 gttccattat cgaacgacaa tgggcagcca gctcacgaac ctgatctttg ccatactgac
    23161 tgacgtcaat tggcggcagc atttcgacaa tcaccagacc gttgtgcagt cgattaagat
    23221 taatcttatt cgaagttgta gagacgcaca cgggaataat cgggacgccc gccgcaattg
    23281 ccgcgtgaaa tgctccagtc ttgaacggta gcaggccgcg accacggctg cgggttcctt
    23341 ccgggaacat ccagatggaa atacggcgtt ttttgaaatg attcacgact tccgcaatgg
    23401 tgccgtgagc tttagtgcga ttgtttctgt cgatcaataa gttgccggtt aaccagtaca
    23461 actgcccgaa gaaggggatc cacagcaagc tctttttacc taccgtcacc gtcggcggtt
    23521 gcacaatgtt cgatgctgtc accatgtcat agttgttctg gtggttagcg atatagatag
    23581 cattgccgta gctttcagca tctgcaggtt tgcggcactc aactttcagg ccgaacagcg
    23641 gcgcaagacg gccaaacata tgcccaaagg tggccacatg tttcgggtta cgcgggctga
    23701 aaaggcagta aatggagccg aatacacaga ctaagatgct gtaaatcacg gtaataataa
    23761 gacgaaagat atatagcata acaccctctg aaggtctgag agactggcat tgtacgtcac
    23821 ctgaaatcag gttagggcat tgttaaaagc cgctctctgg aaaagcgtat tgttaatcgc
    23881 aacgcatgaa taaacaacgg tttcaaggga atttttatcg tttccggggg ttgaatacgc
    23941 tgccggatga cgacttaacg tttcatccgg cgttccttgc aagcgggagg aaacaggccc
    24001 tccccggcat attactcttc gctatcaccg ctgctggcac ggcgaggaga gtcgatctca
    24061 acacgatcga tacgctgcaa accgcgcatc aacgtaccgc ggcgtccacg ttcgccagtg
    24121 actttctgta actcttccgg gcgcagttta attttgcgtt tcccaacatg aatggtcagc
    24181 gtgctttgcg gcggcagaac gtacaattgc gccagaccat cttctccacg cgcggcttct
    24241 gccgatggaa tgttgataat cttgttgcct ttgcccttcg acagctgcgg cagatcgctt
    24301 accgggaaca tcaacatacg gcctgcctga gtgattgcca gcagcatatc ggaagcatct
    24361 tcaatcacca ccggcggcat aacatgggca ttttccggta aggtgatcaa agccttacct
    24421 gcacggttac gcgccaccag atcgttaaag gtgcagacga aaccgtaacc cgcatcggaa
    24481 gccatcagca gtttctgatc gtcgctttcc atcagcatat ggtcaacggt cgccccaggc
    24541 ggcaacgtta atttgccggt gagtggttcg ccctgaccac gcgccgacgg cagcgtaatc
    24601 gggtcgatgg catagctacg accggtggaa tcaacaaaca ctaccggttg gttgctctta
    24661 cctttcaccg ccgctttgaa gctatcaccc gctttataat tcaggcccgg cgcgtcgata
    24721 tcatggcctt tagcgctgcg tacccagccc atctgcgaca gcacaatggt gacaggttca
    24781 gacggcagca tgtcgtgctc gctcatcgct ttcgcttctt cgcgttcctg caacggcgaa
    24841 cgacgatcgt caccgtaggc ttgcgcgtct gcctgcagtt ctttcttcag caggttattc
    24901 attttacgct cggaagccaa aatgccctgc aactggtcgc gctctttttc cagttcactc
    24961 tgctcaccgc gaatcttcat ctcttccagt ttggcaagat gacgcagttt cagttcgagg
    25021 atcgcttccg cctgggtttc cgtaaggcca aaccgcgaca tcagcgccgg tttcggttca
    25081 tcttcattac gaatgatctc aatcacttcg tcgatattga gaaacgccac cagcaaacct
    25141 tcgaggatat gcaggcgctt gaggactttc tccagacgat agttcagtcg gcggcgcacg
    25201 gtatcgcgac ggaacaccag ccattcggag aggatttcca gcaggttttt caccgccgga
    25261 cgaccatcca gaccgatcat attgaggtta atgcgatagc tcttttccag atcggtggta
    25321 gcgaagaggt ggttcatcac ctgatccata tccacgcggt tggaacgcgg cacaatcacc
    25381 agacgggtcg ggttctcgtg gtcagattca tcgcgcagat cgtcaaccat cggcagcttt
    25441 ttgttgcgca tttgcgcagc aatttgctcc agtacgcgcg cacctgaaac ctgatgcggc
    25501 aatgcgctga taaccaccgc gccatcttct ttcttccaca ccgcgcgcat acgcactgaa
    25561 ccacgtccgt tctcgtagat tttacggatc tcggcgcgcg aagtgataat ttccgcttca
    25621 gtcggataat ccggcccctg cacgatatcc agcagctgat cgagcgtggt tttcggttgg
    25681 tcgattaatg cgattgccgc ctgagccact tcacgcaggt tatgcggtgg aatatcggtc
    25741 gccatgccga cggcaatacc ggtggtgccg ttaagcaaaa tgtttggcag acgggcaggc
    25801 agcattttcg gctcctgcaa agtgccgtcg aagtttggca cccagtcagc cgtcccctgc
    25861 cccagctcgc tcaatagcag ctcggaatat ttcgacaacc gggattcggt gtaacgcatt
    25921 gccgcgaacg atttcggatc gtccggcgcg ccccagttcc cctgaccatc aaccagcgga
    25981 taacggtaag agaacggctg cgccatcagg accatcgctt cataacaggc gctatcgccg
    26041 tgcggatggt atttacccag tacgtcaccg acggtacggg ccgatttttt aaatttggcg
    26101 ctggcattca ggcccagttc agacatcgca tacacaatgc ggcgctgaac aggtttcaga
    26161 ccatcaccaa taaacggcaa cgcacggtcc atgatcacgt acatggagta gtttaagtag
    26221 gcgttttccg taaattcatg tagcgcaagg cgctctgcca tatcgctcat taattctgat
    26281 tcctcaactt attcgccagc cttcaaaggg gcaatattgc cggagatact acattatctg
    26341 ccgcgtcgag tcacaggaga tcagcgtgaa tagcgccgcc ggacgtgctc cgacggcgat
    26401 aaaggcatca atgtgccttg atatacaact ctttgctgta gacttgatcg gcatagaggg
    26461 cagcacaagg ttgcgcccat gccacaccac tcggcatggg ggtccgctcc gggcgattcg
    26521 agaagttgag gttatgcgag tccagggaag cctaaagcat caaagtagtc gactgtaagt
    26581 atacggttca gcccagttta gctgtgtctc caccagtgcc ccgcgcctcc tgccataagt
    26641 gcggcttgct catgggtacc cccgagacgg cttacggcgc accggataat aaatttcgcg
    26701 tatacatggt attccttacc ggagaaatta taagtccaac aacaatacgc ctgtggcatt
    26761 gttcgctcaa acttatcgcg agtgatttgg ctcacactcc ggtaaagatt ccccatcacg
    26821 ccaacggcac ataaacatcc gtttccagtc gctgctctgt caccccttcg gcaagattgg
    26881 tgtagtgaaa cagaatcggt gctttacgca ttttctcgcc gcttgcaggc agccagtggc
    26941 gaataatgcc ccatatcgtg tgtgaaatat cgtccagctc gccaacgtgg cgggccacgg
    27001 cataacgtcc accggtaagt tcaccattgc tcacaccata acgattatcg ggaatcggtt
    27061 cgctaacgct gccgcagata tcaaagcgaa acgcttccgg tgcggtggtg gcagggtcgt
    27121 cccaggcgac gccaaaagtc tggctttggt taacaggaga aagccccgtc tctttacgcc
    27181 acatgataaa tttcgccaca ctgtagttga gcaactcagg gctacagcgg tgcggcaaca
    27241 tcgccacagg gattgatggg aaatcgataa tgtttacatc cagtgtcagg tttgtcattt
    27301 tgcctccctg cgaaattatt cccgggaacg cgtcccggga gcggtaacaa ttacggattt
    27361 actttgcgga tctgtttgac gtcaatttca acagaattcc agtctttatc gacttcaccc
    27421 tgaatctcaa ccgtatcttt cggcgtcacc gtcacaccgt tccagcgttt gtggtcgata
    27481 tcaacattga tagtaccgct ggcatcttta aacacgtaga gatcgtcaga gatgcgttca
    27541 acgatattgc cgcgcagggt tacccaggtg tcgtcacgca gggattttgc gctttctacg
    27601 gtcgttacgc tgccgttcgg cccctggaat cctccggcct gactttgcgt tgccgatggg
    27661 ccagaaaaac cgccctgctc tgctgccatc accggtgcgc tgcacagggc cattactgcg
    27721 attactgctg cgaatttttt catgtttatt actcccttta atgtctgttt ccgagcattt
    27781 aacaagatag tccttaacaa cttcttaagg gaaaaaaata aaatttagtg ctgtacagag
    27841 cgcgttacaa cacggtttac tggcagcaaa tacggttatc gcagggatga aaaaatgcga
    27901 attttactga tagaagatga catgctgatt ggcgacggca tcaaaacggg ccttagtaaa
    27961 atgggtttta gcgtcgactg gtttacacaa ggtcgtcagg gaaaagaggc gctttatagc
    28021 gcgccttatg atgcggtgat cctggattta accttaccag gcatggatgg tcgcgatatt
    28081 ttgcgcgaat ggcgagaaaa aggtcagcgt gagccggtac tgatcctgac cgcgcgcgat
    28141 gcgctggagg aacgtgtaga agggctgcgt ctgggagctg acgattatct gtgtaaacct
    28201 tttgcgttga tagaagtcgc cgccaggctg gaagctctga tgcgccgaac caacggccag
    28261 gccagcaacg agctgcgcca cggtaacgtc atgctcgacc ccggcaaacg tatcgccacg
    28321 ctggctggcg aacccttaac actgaaacca aaagaatttg ccctgctgga attactgatg
    28381 cgtaacgctg gtcgggtact gccgcgcaaa ctgattgaag agaaactgta tacctgggac
    28441 gaagaggtca ccagtaatgc cgttgaagtg catgtgcatc atctgcgacg caaactcggt
    28501 agtgatttta ttcgtaccgt gcatggtatt ggctacacat taggtgagaa atgaaattta
    28561 cccaacgtct tagtctgcgc gtcaggctga cgctaatctt tttaattctg gcctcggtga
    28621 cctggctgct ttccagcttt gtcgcctgga aacaaacaac ggataacgtc gatgaattgt
    28681 tcgacaccca actgatgctg tttgccaagc ggttaagtac gctcgatctc aacgaaatca
    28741 acgcggcgga tcgcatggca cagacgccaa ataaattaaa acacggtcat gttgatgacg
    28801 atgcgctgac ctttgccatc tttacccacg acggcagaat ggtccttaac gatggcgata
    28861 acggagaaga tattccttat agctatcaac gggaaggttt tgctgacggg caactggtgg
    28921 gcgataaaga tcaatggcgt tttgtctgga tgacctcacc tgatggcaaa tatcgcatcg
    28981 ttgttggtca ggaatgggaa taccgtgaag acatggcgct ggcgattgtt gccgggcaat
    29041 tgatcccgtg gctggtcgca ctgccgatta tgttaatcat catgatggta ctattgggtc
    29101 gtgaactcgc gccgctgaac aaactggcgc tggcgctgcg tatgcgtgac cctgactcgg
    29161 aaaaaccact aaacgcgact ggcgtaccca gcgaagtgcg tccgttggtt gagtcgctaa
    29221 atcaactgtt cgcccgcaca catgcgatga tggttcgtga acgacgcttt acctccgacg
    29281 cagctcacga actacgtagc ccgttaacgg cgctgaaagt gcaaaccgaa gttgcgcagc
    29341 tttctgacga tgatccgcaa gcgcggaaaa aagcgctgct tcaattacat tacgggatcg
    29401 atcgcgctac tcgtctggtt gatcaactgc tcactctatc gcggctggac tcactggata
    29461 accttcagga cgtcgcggag atcccgcttg aagatctcct gcaatcgtcg gtgatggata
    29521 tttaccacac ggcgcagcag gcgaaaattg acgtgcgact gacactcaat gcccacggca
    29581 tcaaacgcac cggacaaccg ctattgctaa gtttgttggt gcgaaatttg ctggataacg
    29641 ccgtgcgcta cagtccacag ggcagcgtga tagacgtcac gctgaatgct gataatttca
    29701 tcgtgaggga taacggcccc ggtgtgatgc cagaggctct ggcgcgaatt ggcgaacgct
    29761 tctatcgccc ccccggacaa accgctaccg gcagtggact tgggctatcg attgtccagc
    29821 gaatcgccaa attgcatggc atgaatgttg agtttgggaa tgcggaacaa ggtggatttg
    29881 aggcgaaggt aagctggtaa cttctctgtc tatgagagcc gttaaaacga ctctcataga
    29941 ttttactaat agcaaaatat aaaccgtccc caaaaaagcc accaaccaca aaccagacaa
    30001 ataccgagcg aaaatacata tacccaaaac tcgaacattt cccgcataaa gagttttctt
    30061 aagataagaa taataagtgg cgtaagaaga aaaaatgctg caatcattgc ttgcaatata
    30121 cgatcttcgc ctgaaacgga aggtatactg caaatattgc ctcccgactc aagcatccag
    30181 tcatacttat tgaaagcaaa aaaagcatct attaaccaat aagtaagcat tatgtataac
    30241 agagcttcaa atattgtttg aattttatgc tttaacatat atcagtacgc tcataaaaat
    30301 ccatttataa ttatcaacat gacacgttga tattttcatc ttttacttat tcaaagccat
    30361 attttcaatc ccaaaaaaaa ccgaaccaaa cgtgtaaatt attccggtgc gagtaagaat
    30421 tatgaggaat ggctatcagt attgtcattt tcagaaaata tttatcctgc atcggtgagt
    30481 cagagctaga tcagactttt gctaaattcg caaaagactt tgcacatttt gctaatttca
    30541 ccgtaccgct ctgtgacgta ctatagtcga caaacgtctc accttgaggt taaaaaatga
    30601 gtaacatcct gattatcaac ggcgcgaaaa aattcgccca ctccaatggt caactgaacg
    30661 acaccctgac cgaagtcgcg gatggcacac tgcgcgacct cgggcatgat gtccgcatcg
    30721 ttcgcgccga cagcgactac gttgtcaaag cggaagtaca aaactttctc tgggctgatg
    30781 tggtgatctg gcagatgcca ggctggtgga tgggcgcgcc gtggacagtg aaaaaatata
    30841 ttgatgatgt attcaccgaa ggtcatggaa cgctgtatgc cagcgatggt cgtacccgca
    30901 aagatccgtc gaaaaaatac ggttccggcg gcctggtaca gggcaaaaaa tatatgcttt
    30961 ctctaacctg gaacgcacca atggaagcct tcaccgaaaa agatcagttc ttccacggcg
    31021 ttggcgttga cggtgtgtat ctgccgttcc ataaagcaaa ccaattcctc ggtatggaac
    31081 cgctgccgac atttatcgct aatgacgtga taaaaatgcc tgatgttccc cgctatactg
    31141 aagaatatcg caagcatctt gtggaaattt ttggttaact agagctcagg ctttagaagg
    31201 agttaaccat gcttaccgta atcgcagaaa tccgtactcg tcctggtcaa catcaccgtc
    31261 aggcggtatt ggatcagttt gctaaaatcg ttccaaccgt actgaaagaa gaaggttgcc
    31321 acggctatgc gccaatggtg gattgcgctg ctggcgtgag tttccagtct atggcaccgg
    31381 attctatcgt gatgattgag cagtgggaaa gcatcgcgca tcttgaagcg catctgcaaa
    31441 ccccgcacat gaaggcgtac agcgaagcca taaaaggcga cgtgctggag atgaatattc
    31501 gtattctgca gccagggatt taatatttct gaaaagaggc cggtgctgct tgttgccggc
    31561 catttatttt cactcttccg ccgtttgtaa ccgtgctttt atctgttcgt aatattcatt
    31621 attaatcaga taaaatctca tgatgagtcc ggtaagcagg ttaagtatcg cgggaatgat
    31681 cgtcattaac aggcagatcc cccacagcgc ctgtggtgtt tgttctacgc ctggttgata
    31741 atccagatag gctaaagcga ttccgataaa gccccctgcc agccccatac cgaacttttg
    31801 gaaaaagaga atcccgccaa atgccaggcc agaaacacgt tgccccgttt tcatttcacc
    31861 gtaatccacg gactcagcaa tggatgccca ataaatggga agctggatat ccgtcaggaa
    31921 agtcaccaca atataaaatg taaaagctag cactatagaa tttggttgca cgaaatacat
    31981 cgcaccaccc accacgaacg ccagtaattg ggtataacga aatattttta ttttgtcata
    32041 gagacgagta agccaggtgc aagcgatcat agccagaact gaggcgatca cgcctgaagt
    32101 taaaaacggt gaaattaaag catccccacc actcaggtaa tattttgcat aatatgcagc
    32161 gacagagtta cgaataatcc cgccaaacat aatgatcgca attacagcgc ccaaaatgag
    32221 ccattgatca tttttgatca gtaaccgaaa ctgcgcggcc ataccgagac tgggttttgg
    32281 atggtagatg cgctctctca cgctaaaaaa acaatacagg cataaacacg ttgccagaat
    32341 acccattgtc cccattgcta tttgataacc cagttgtacg ttattcttcc caagatacat
    32401 tgcagataaa ggaacaataa ttgttacggc gaacatggca atttttgtca taacaaaacg
    32461 ataaccattg gcgctcaatc tctcttgtgg atcatccgtg ataacgctga ttaatgaaac
    32521 ataaggaata gcgattaacg tataggtcaa ggtaagtaac acataggtag cccaggccca
    32581 taaaagctta actgaataat cggtatcagg tgtggtgaac atcaaccaaa tgcttatccc
    32641 aaacggtatt gacataaaaa gcaaccatgg ccgatatttt ccccaacgtg tattcgttat
    32701 gtctgtcatt gttcccacaa ctggatcaat cacagcatca agaatacgta cagaaaataa
    32761 cagaatacct aagtcgacgg gtttcagacc aaatacatcc gtgtaaaaat aagtgatgat
    32821 catggctaaa gacatcatta ctatcgcaat ggccatatta ccggcaccaa aacctatctt
    32881 ttcatttatt gtcagtttca tacacagcac tcattaatca catgaaatta tattaaaaac
    32941 aaatgtatcg gaactcattc agcacataac tttacgattg agaataaatg cattggtaga
    33001 taccacaaca aaccactgag ttaatattga gcagcatcac ataaaaac
//
LOCUS       DAPGUL010000046        32558 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.046, whole genome shotgun sequence.
ACCESSION   DAPGUL010000046 DAPGUL010000000
VERSION     DAPGUL010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 32558)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32558)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32558
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.046"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(250..2010)
                     /locus_tag="RHX21_002301"
     CDS             complement(250..2010)
                     /locus_tag="RHX21_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415425.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HDV1987472.1"
                     /translation="MTQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVW
                     SVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVH
                     YPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTR
                     QSDNQTVYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPE
                     IPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGA
                     HPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDL
                     FKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSD
                     IYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLG
                     LATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQ
                     TLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAH
                     QSLLKAYEKLQRAKAAFWAK"
     gene            2140..2832
                     /locus_tag="RHX21_002302"
     CDS             2140..2832
                     /locus_tag="RHX21_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HDV1987473.1"
                     /translation="MKAFDLHRMAFDKVPFDFLGEVALRSLYTFVLVFLFLKMTGRRG
                     VRQMSLFEVLIILTLGSAAGDVAFYDDVPMVPVLIVFITLALLYRLVMWLMAHSEKLE
                     DLLEGKPVVIIEDGELAWSKLNNSNMTEFEFFMELRLRGVEQLGQVRLAILETNGQIS
                     VYFFEDDKVKPGLLILPSDCTQRYKVVPESADYACIRCSEIIHMKAGEKQLCPRCANP
                     EWTKASRAKRVT"
     gene            3031..4119
                     /gene="serC"
                     /locus_tag="RHX21_002303"
     CDS             3031..4119
                     /gene="serC"
                     /locus_tag="RHX21_002303"
                     /EC_number="2.6.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoserine/phosphohydroxythreonine
                     transaminase"
                     /protein_id="HDV1987474.1"
                     /translation="MAQIFNFSSGPAMLPAEVLKQAQQELRDWNGLGTSVMEVSHRGK
                     EFIQVAEEAEKDFRDLLNVPSNYKVLFCHGGGRGQFAAVPLNILGDKTTADYVDAGYW
                     AASAIKEAKKYCTPNVFDAKVTVDGLRAVKPMREWQLSDNAAYMHYCPNETIDGIAID
                     ETPDFGKDVVVAADFSSTILSRPIDVSRYGVIYAGAQKNIGPAGLTIVIVREDLLGKA
                     NIACPSILDYSILNDNGSMFNTPPTFAWYLSGLVFKWLKANGGVAEMDKINQQKAELL
                     YGVIDNSDFYRNDVAKANRSRMNVPFQLADSALDKLFLEESFAAGLHALKGHRVVGGM
                     RASIYNAMPLEGVKALTDFMVEFERRHG"
     gene            4190..5473
                     /gene="aroA"
                     /locus_tag="RHX21_002304"
     CDS             4190..5473
                     /gene="aroA"
                     /locus_tag="RHX21_002304"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HDV1987475.1"
                     /translation="MESLTLQPIASVDGTINLPGSKSVSNRALLLAALAHGKTVLTNL
                     LDSDDVRHMLNALTALGVSYTLSADRTRCEIIGNGGPLHAEGALELFLGNAGTAMRPL
                     AAALCLGSNDIVLTGEPRMKERPIGHLVDALRLGGAKITYLEQENYPPLRLQGGFTGG
                     NVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQ
                     HYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIKGGTVKVTGIGRNSMQGDIRF
                     ADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNI
                     YNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFS
                     LVALSDTPVTILDPKCTAKTFPDYFEQLARISQAA"
     gene            5642..6406
                     /gene="ycaL"
                     /locus_tag="RHX21_002305"
     CDS             5642..6406
                     /gene="ycaL"
                     /locus_tag="RHX21_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706828.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallopeptidase YcaL"
                     /protein_id="HDV1987476.1"
                     /translation="MKNTKLLLAIATSAALLTGCQNTHGIDTNMAISSGLNAYKAATL
                     SDADAKAIANQGCAEMDSGNQVASKSSKYGKRLAKIAKALGNNINGTPVNYKVYMTSD
                     VNAWAMANGCVRVYSGLMDMMNDNEIEGVLGHELGHVALGHSLAEMKASYAIVAARDA
                     ISATSGVASQLSRSQLGDIAEGAINAKYSRDKESEADDFSFDLLKKRGISTQGLVGSF
                     EKLASLDGGRTQSMFDSHPPSTERAQHIRDRIASGK"
     gene            6579..7262
                     /gene="cmk"
                     /locus_tag="RHX21_002306"
     CDS             6579..7262
                     /gene="cmk"
                     /locus_tag="RHX21_002306"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HDV1987477.1"
                     /translation="MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLA
                     LAALHHHVDVASEDALVPLASHLDVRFVSTNGNLEVILEGEDVSGEIRTQEVANAASQ
                     VAAFPRVREALLRRQRAFRELPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRML
                     QLQEKGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTTLSIEQVIEKALQ
                     YARQKLALA"
     gene            7373..9046
                     /gene="rpsA"
                     /locus_tag="RHX21_002307"
     CDS             7373..9046
                     /gene="rpsA"
                     /locus_tag="RHX21_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HDV1987478.1"
                     /translation="MTESFAQLFEESLKEIETRPGSIVRGVVVAIDKDVVLVDAGLKS
                     ESAIPAEQFKNAQGELEIQVGDEVDVALDAVEDGFGETLLSREKAKRHEAWITLEKAY
                     EDAETVTGVINGKVKGGFTVELNGIRAFLPGSLVDVRPVRDTLHLEGKELEFKVIKLD
                     QKRNNVVVSRRAVIESENSAERDQLLENLQEGMEVKGIVKNLTDYGAFVDLGGVDGLL
                     HITDMAWKRVKHPSEIVNVGDEITVKVLKFDRERTRVSLGLKQLGEDPWVAIAKRYPE
                     GTKLTGRVTNLTDYGCFVEIEEGVEGLVHVSEMDWTNKNIHPSKVVNVGDVVEVMVLD
                     IDEERRRISLGLKQCKANPWQQFAETHNKGDRVEGKIKSITDFGIFIGLDGGIDGLVH
                     LSDISWNVAGEEAVREYKKGDEIAAVVLQVDAERERISLGVKQLAEDPFNNWVALNKK
                     GAIVTGKVTAVDAKGATVELADGVEGYLRASEASRDRVEDATLVLSVGDEVEAKFTGV
                     DRKNRAISLSVRAKDEADEKDAIATVNKQEDANFSNNAMAEAFKAAKGE"
     gene            9206..9490
                     /gene="ihfB"
                     /locus_tag="RHX21_002308"
     CDS             9206..9490
                     /gene="ihfB"
                     /locus_tag="RHX21_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006819309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit beta"
                     /protein_id="HDV1987479.1"
                     /translation="MTKSELIERLATQQSHIPAKTVEDAVKEMLEHMASTLAQGERIE
                     IRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG"
     gene            9697..11961
                     /locus_tag="RHX21_002309"
     CDS             9697..11961
                     /locus_tag="RHX21_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309023.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC family protein"
                     /protein_id="HDV1987480.1"
                     /translation="MKITTVGVCIICGIFPLLILPQLPGTLTLAFLTLFACVLAFIPV
                     KTVRYIALTLLFFVWGILSAKQILWAGETLTGATQDAIVEITATDGMTTHYGQITHLQ
                     GRRIFPAPGLVLYGEYLPQAVCAGQQWSMKLKVRAVHGQLNDGGFDSQRYAIAQHQPL
                     TGRFLQASVIEPNCSLRAQYLASLQTTLQPYPWNAVILGLGMGERLSVPKEIKNIMRD
                     TGTAHLMAISGLHIAFAALLAAGLIRSGQIFLPGRWIHWQIPLIGGICCAAFYAWLTG
                     MQPPALRTVVALATWGMLKLSGRQWSGWDVWICCLAAILLMDPVAILSQSLWLSAAAV
                     AALIFWYQWFPCPEWQLPPVLRAVVSLIHLQLGITLLLMPVQIVIFHGISLTSFIANL
                     LAIPLVTFITVPLILAAMVVHLSGPLILEQGLWFLADRSLALLFWGLKSLPEGWINIA
                     ERWQWLSFSPWFLLVVWRLNAWRTLPAMCVAVGLLMCWPLWQKPRPDEWQVYMLDVGQ
                     GLAMVIARNGKAILYDTGLAWPEGDSGQQLIIPWLHWHNLEPEGVILSHEHLDHRGGL
                     DSILHTWPMLWIRSPLNWEHHQPCVRGEAWQWQGLRFSVHWPLQASNDKGNNHSCVVK
                     VDDGTNSILLTGDIEVPAEQKMLSRYWQQVQTTLLQVPHHGSNTSSSLPLIQRVNGKV
                     ALASASRYNAWRLPSNKVKHRYQQQGYQWLDTPHQGQVTVNFSAQGWRISSLREQILP
                     RWYHQWFGVPVDNG"
     gene            11998..13746
                     /gene="msbA"
                     /locus_tag="RHX21_002310"
     CDS             11998..13746
                     /gene="msbA"
                     /locus_tag="RHX21_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A ABC transporter ATP-binding
                     protein/permease MsbA"
                     /protein_id="HDV1987481.1"
                     /translation="MHNDKDLSTWQTFRRLWPTIAPFKAGLIVAGVALILNAASDTFM
                     LSLLKPLLDDGFGKTDRSVLVWMPLVVIGLMILRGITSYVSSYCISWVSGKVVMTMRR
                     RLFGHMMGMPVSFFDKQSTGTLLSRITYDSEQVASSSSGALITVVREGASIIGLFIMM
                     FYYSWQLSIILIVLAPIVSIAIRVVSKRFRNISKNMQNTMGQVTTSAEQMLKGHKEVL
                     IFGGQEVETKRFDKVSNRMRLQGMKMVSASSISDPIIQLIASLALAFVLYAASFPSVM
                     DSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFTILDSEQEKDEGKRV
                     IERATGDVEFRNVTFTYPGRDVPALRNINLKIPAGKTVALVGRSGSGKSTIASLITRF
                     YDIDEGEILMDGHDLREYTLASLRNQVALVSQNVHLFNDTVANNIAYARTEQYSREQI
                     EEAARMAYAMDFINKMDNGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEAT
                     SALDTESERAIQAALDELQKNRTSLVIAHRLSTIEKADEIVVVEDGVIVERGTHNDLL
                     EHRGVYAQLHKMQFGQ"
     gene            13743..14729
                     /gene="lpxK"
                     /locus_tag="RHX21_002311"
     CDS             13743..14729
                     /gene="lpxK"
                     /locus_tag="RHX21_002311"
                     /EC_number="2.7.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetraacyldisaccharide 4'-kinase"
                     /protein_id="HDV1987482.1"
                     /translation="MIEKIWSGESPLWRLLLPLSWLYGLVSGAIRLCYKLKLKRAWRA
                     PVPVVVVGNLTAGGNGKTPVVVWLVEQLQQRGIRVGVVSRGYGGKAESYPLLLSADTT
                     TAQAGDEPVLIYQRTDAPVAVSPVRSDAVKAILAQHPDVQIIVTDDGLQHYRLARDVE
                     IVVIDGVRRFGNGWWLPAGPMRERAGRLKSVDAVIVNGGVPRSGEIPMHLLPGQAVNL
                     RTGTRCDVAQLEHVVAMAGIGHPPRFFATLKMCGVQPEKCVPLADHQSLNHADVSALV
                     SAGQTLVMTEKDAVKCRAFAEENWWYLPVDAQLSGDEPAKLLTQLTSLASGN"
     gene            14766..15998
                     /locus_tag="RHX21_002312"
     CDS             14766..15998
                     /locus_tag="RHX21_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaQ family DNA glycosylase"
                     /protein_id="HDV1987483.1"
                     /translation="MSLPHLSLADARNLHLAAQGLLNKPRRQASLEDIPATISRMSLL
                     QIDTINIVARSPYLVLFSRLGNYPAQWLDESLARGELMEYWAHEACFMPRSDFRLIRH
                     RMLAPEKMGWKYKDAWMQEHEAEIAQLIQHIHDKGPVRSADFEHPRKGASGWWEWKPH
                     KRHLEGLFTAGKVMVIERRNFQRVYDLTHRVMPDWDDERDLVSQTEAEIIMLDNSARS
                     LGIFREQWLADYYRLKRPALAAWREARAEQQQIIAVHVEKLGNLWLHADLLPLLERAL
                     AGKLTATHSAVLSPFDPVVWDRKRAEQLFDFSYRLECYTPAPKRQYGYFVLPLLHRGQ
                     LVGRMDAKMHRQTGILEVISLWLQEGIKPTTMLQKGLRQAITDFASWQQATRVTLGRC
                     PQGLFTDCRTGWEIDPVA"
     gene            16050..16232
                     /gene="ycaR"
                     /locus_tag="RHX21_002313"
     CDS             16050..16232
                     /gene="ycaR"
                     /locus_tag="RHX21_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YcaR"
                     /protein_id="HDV1987484.1"
                     /translation="MDHRLLEIIACPVCNGKLWYNQEKQELICKLDNLAFPLRDGIPV
                     LLETEARVLTADESKS"
     gene            16229..16975
                     /gene="kdsB"
                     /locus_tag="RHX21_002314"
     CDS             16229..16975
                     /gene="kdsB"
                     /locus_tag="RHX21_002314"
                     /EC_number="2.7.7.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="HDV1987485.1"
                     /translation="MSFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGADR
                     IIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCAFSDDTVIVNVQGDEP
                     MIPATIIRQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGYALYFSRATI
                     PWDRDRFAEGLETVGDNFLRHLGIYGYRAGFIRRYVNWQPSPLEHIEMLEQLRVLWYG
                     EKIHVAVAQEVPGTGVDTPEDLERVRAEMR"
     gene            17129..18022
                     /locus_tag="RHX21_002315"
     CDS             17129..18022
                     /locus_tag="RHX21_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcbJ family phosphotransferase"
                     /protein_id="HDV1987486.1"
                     /translation="MEQLRAELSHLLGEKLSRIECVNEKADTALWALYDSQGNPMPLM
                     ARSFSTPGKARQLAWKTTMLARSGTVRMPTIYGVMTHEEHPGPDVLLLERMRGVSVEA
                     PARTPERWEQLKDQIVEALLAWHRQDSRGCVGAVDNTQENFWPSWYRQHVEVLWTTLN
                     QFNNTGLTMQDKRILFRTRECLPALFEGFNDNCVLIHGNFCLRSMLKDSRSDQLLAMV
                     GPGLMLWAPREYELFRLMDNSLAEDLLWSYLQRAPVAESFIWRRWLYVLWDEVAQLVN
                     TGRFSRRNFDLASKSLLPWLA"
     gene            complement(17999..18778)
                     /gene="elyC"
                     /locus_tag="RHX21_002316"
     CDS             complement(17999..18778)
                     /gene="elyC"
                     /locus_tag="RHX21_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope biogenesis factor ElyC"
                     /protein_id="HDV1987487.1"
                     /translation="MLFTLKKVIGNMLLPLPLMLLIIGAGLALLWFSRFQKTGKIFIS
                     IGWLALLLLSLQPVADRLLRPIESTYPTWNNSQKVDYIVVLGGGYTWNPQWAPSSNLI
                     NNSLPRLNEGIRLWRENPGSKLIFTGGVAKTNTVSTAEVGARVAQSLGVPHEQIITLD
                     LPKDTEEEAAAVKQAIGDAPFLLVTSASHLPRAMIFFQQEGLNPLPAPANQLAIDSPL
                     NPWERAIPSPVWLMHSDRVGYETLGRIWQWLKGSSGEPRQE"
     gene            18914..19699
                     /gene="cmoM"
                     /locus_tag="RHX21_002317"
     CDS             18914..19699
                     /gene="cmoM"
                     /locus_tag="RHX21_002317"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine 5-oxyacetic acid(34)
                     methyltransferase CmoM"
                     /protein_id="HDV1987488.1"
                     /translation="MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDHVLAEMGPQ
                     KLRVLDAGGGEGQTAIKMAERGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAA
                     QDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNM
                     VAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREK
                     HQQRDCYEALLELETRYCRQEPYITLGRYIHVTARKPQSKDKV"
     gene            19696..21018
                     /gene="mukF"
                     /locus_tag="RHX21_002318"
     CDS             19696..21018
                     /gene="mukF"
                     /locus_tag="RHX21_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukF"
                     /protein_id="HDV1987489.1"
                     /translation="MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLD
                     GEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYR
                     LTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAEEGGDEFHWHRNVYAPL
                     KYSVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLREL
                     QDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIG
                     YDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDEPWALTYANADRLLDMRDEEMALR
                     DEEVTGELPEDLEYEEFNEIREQLAAIIEEQLAVYKTRQVPLDLGLVVREYLSQYPRA
                     RHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY"
     gene            20999..21703
                     /gene="mukE"
                     /locus_tag="RHX21_002319"
     CDS             20999..21703
                     /gene="mukE"
                     /locus_tag="RHX21_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415443.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukE"
                     /protein_id="HDV1987490.1"
                     /translation="MSSTNIEQVMPVKLAQALANPLFPALDSALRSGRHIGLDELDNH
                     AFLMDFQEYLEEFYARYNVELIRAPEGFFYLRPRSTTLIPRSVLSELDMMVGKILCYL
                     YLSPERLANEGIFTQQELYDELLTLADEAKLLKLVNNRSTGSDVDRQKLQEKVRSSLN
                     RLRRLGMVWFMGHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMPIENHLQ
                     LNDETEENQPDSGEEE"
     gene            21703..26163
                     /gene="mukB"
                     /locus_tag="RHX21_002320"
     CDS             21703..26163
                     /gene="mukB"
                     /locus_tag="RHX21_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukB"
                     /protein_id="HDV1987491.1"
                     /translation="MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTM
                     AAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVV
                     GVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLNERQARVLPLNELKDKLEAM
                     EGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLR
                     DYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMR
                     HANERRVHLDKALEFRRELHTSRQQLAAEQYKHVDMARELAEHNGAEGDLEADYQAAS
                     DHLNLVQTALRQQEKIERYEADLDELQIRLEEQNEVVAEAIERQEENEARAEAAELEV
                     DELKSQLADYQQALDVQQTRAIQYNQAIAALNRAKELCHLPDLTADSAAEWLETFQAK
                     ELEATEKMLSLEQKMSMAQTAHSQFEQAYQLVVAINGPLARNEAWDVARELLREGVDQ
                     RHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKNFDIDELEALHQELEARI
                     ASLSDSVSNAREERMALRQEQEQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEEFTS
                     SQDVTEYLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAERFG
                     GVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQVTEHLEGLTDCPEDLYLIEGD
                     PQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPEVPLFGRAARESRIESLHAEREVLS
                     ERFATLSFDVQKTQRLHQAFSRFIGSHLAVAFESDPEAEIRQLNSRRVELERALSNHE
                     NDNQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQ
                     FGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFALTEVAQRRAHFSY
                     SDSAEMLSGNSDLNEKLRERLEQAEAERTRAREALRGHAAQLSQYNQVLASLKSSYDT
                     KKELLNDLQRELQDIGVRADSGAEERARIRRDELHAQLSNNRSRRNQLEKALTFCEAE
                     MDNLTRKLRKLERDYFEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADDL
                     RSMSDKALGALRLAVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQHLRERIRQDIIR
                     TDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGL
                     QNVSFGQVNSVRLNVNVRETHAMLLDVLSEQHEQHQDLFNSNRLTFSEALAKLYQRLN
                     PQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSIL
                     VMVVQSWEDESRRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPE
                     NISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGSDEAPSQAS"
     gene            26424..28271
                     /gene="ldtD"
                     /locus_tag="RHX21_002321"
     CDS             26424..28271
                     /gene="ldtD"
                     /locus_tag="RHX21_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HDV1987492.1"
                     /translation="MLLNMMCGRRLSAISLCLAVTFAPLFNAQADEPEVIPGDSPVAV
                     SEQGEALPQAQATAIMAGIQPLPEGAAEKARTQIESQLPAGYKPVYLNQLQLLYAARD
                     MQPMWENRDAVKAFQQQLAEVAIAGFQPQFNKWVELLTDPGVNGMARDVVLSDAMMGY
                     LHFIANIPVKGTRWLYSSKPYALATPPLSVINQWQLALDKGQLPTFVAGLAPQHPQYA
                     AMHESLLALLSDTKPWPQLTGKATLRPGQWSNDVPALREILQRTGMLDGGPKITLPGD
                     DTPTDAVVSPSAVTVETAETKPMDKQTTSRSKPAPAVRAAYDNELVEAVKRFQAWQGL
                     GADGAIGPATRDWLNVTPAQRAGVLALNIQRLRLLPTELSTGIMVNIPAYSLVYYQNG
                     NQVLDSRVIVGRPDRKTPMMSSALNNVVVNPPWNVPPTLARKDILPKVRNDPGYLESH
                     GYTVMRGWNSREAIDPWQVDWSTITASNLPFRFQQAPGPRNSLGRYKFNMPSSEAIYL
                     HDTPNHNLFKRDTRALSSGCVRVNKASDLANMLLQDAGWNDKRISDALKQGDTRYVNI
                     RQSIPVNLYYLTAFVGADGRTQYRTDIYNYDLPARSSSQIVSKAEQLIR"
     gene            28452..29000
                     /locus_tag="RHX21_002322"
     CDS             28452..29000
                     /locus_tag="RHX21_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcbK family protein"
                     /protein_id="HDV1987493.1"
                     /translation="MDKFDANRRKLLALGGVALGAAILPTPAFATLSTPRPRILTLNN
                     LHTGESIKAEFFDGRGYIQEELAKLNHFFRDYRANKIKSIDPGLFDQLYRLQGLLGTR
                     KPVQLISGYRSIDTNNELRARSRGVAKKSYHTKGQAMDFHIEGIALSNIRKAALSMRA
                     GGVGYYPRSNFVHIDTGPARHW"
     gene            29027..29674
                     /gene="gloC"
                     /locus_tag="RHX21_002323"
     CDS             29027..29674
                     /gene="gloC"
                     /locus_tag="RHX21_002323"
                     /EC_number="3.1.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003035823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase GloC"
                     /protein_id="HDV1987494.1"
                     /translation="MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDD
                     SGLTLMQILLTHGHLDHVGAAAELAQHYGVPVFGPEKEDEFWLQGLPAQSRMFGLEEC
                     QPLTPDRWLNEGDTISIGNVTLQVLHCPGHTPGHVVFFDDRAKLLISGDVIFKGGVGR
                     SDFPRGDHNQLISSIKDKLLPLGDDVTFIPGHGPLSTLGYERLHNPFLQDEMPVW"
     gene            complement(29896..31086)
                     /gene="aspC"
                     /locus_tag="RHX21_002324"
     CDS             complement(29896..31086)
                     /gene="aspC"
                     /locus_tag="RHX21_002324"
                     /EC_number="2.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009653304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate transaminase"
                     /protein_id="HDV1987495.1"
                     /translation="MFENITAAPADPILGLADLFRADERPGKINLGIGVYKDETGKTP
                     VLTSVKKAEQYLLENETTKNYLGIDGIPEFGRCTQELLFGKGSALINDKRARTAQTPG
                     GTGALRVAADFLAKNTSVKRVWVSNPSWPNHKSVFNSAGLEVREYAYYDAENHTLDFD
                     ALINSLNEAQAGDVVLFHGCCHNPTGIDPTLEQWQTLAQLSVEKGWLPLFDFAYQGFA
                     RGLEEDAEGLRAFAAMHKELIVASSYSKNFGLYNERVGACTLVAADSETVDRAFSQMK
                     AAIRANYSNPPAHGASVVATILSNDALRAIWEQELTDMRQRIQRMRQLFVNTLQEKGA
                     NRDFSFIIKQNGMFSFSGLTKEQVLRLREEFGVYAVASGRVNVAGMTPDNMAPLCEAI
                     VAVL"
     gene            complement(31271..32359)
                     /gene="ompF"
                     /locus_tag="RHX21_002325"
     CDS             complement(31271..32359)
                     /gene="ompF"
                     /locus_tag="RHX21_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpF"
                     /protein_id="HDV1987496.1"
                     /translation="MMKRNILAVIVPALLVAGTANAAEIYNKDGNKVDLYGKAVGLHY
                     FSKGNGENSYGGNGDMTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQTGNK
                     TRLAFAGLKYADVGSFDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVAT
                     YRNSNFFGLVDGLNFAVQYLGKNERDTARRSNGDGVGGSISYEYEGFGIVGAYGAADR
                     TNLQEAQPLGNGKKAEQWATGLKYDANNIYLAANYGETRNATPITNKFTNTSGFANKT
                     QDVLLVAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVD
                     YIINQIDSDNKLGVGSDDTVAVGIVYQF"
BASE COUNT         7958 a         7889 c         8736 g         7975 t
ORIGIN      
        1 aattttaaaa attaacaaat gagttgaatt ttttccgcat cctccgctaa aacagttaat
       61 taaaagggag catcaggcga ataaagtaac aatatcgatc gtatttatta aatacaaatt
      121 accgatattt aaccttataa ttacaattat tttattaatg caaatatatg taaagcgggg
      181 cattaaaaaa acgccccgta atataactca gactaatcat taagcctaca ttgcgtaggc
      241 tatttgattt tattttgccc agaatgctgc tttggcgcgc tgcagctttt cgtaggcctt
      301 caacaacgac tgatgcgcag caaacgcgtg cagatcgcta tctaccggtt gcaggccgta
      361 aaacgccgct tcgccgctca ttgccgcact ggcggcttct acggcatctg cgccgtacat
      421 gcgaacaaac gcattcagat attgcagcgg ctggcgatct tcttcctgtg ccagtaataa
      481 caacgtttgc aggcagcgat aatagttggc gcgttccgga ctaaatactg atgagttaaa
      541 ctccatcgtc cattcggtcc agaccagagc ctgttccaga tcgccaccag ccagcgccag
      601 catggctttt aattcaccga tacgcagggt gtaccaaccg ttatccgacc cggtcgccag
      661 acccaacagc tcacgcacgc gggtaaagtc atcaaaacct tcttcatcca gttgctcgat
      721 gaggttcagg taatcttctt tttcccactc gctgcctggt agcgaaagaa tcgtttcacg
      781 taaatggctg cccatactgt tattcgcgag ccacagatct tcagccggat aaatatcgga
      841 catgccaggc acgataatac ggcaagcata aacgcccaga tgctcgtaat cggcaatata
      901 aacttcttta tcttctttgt tgaagatagc catcagtgtg gcgaactctt cttccgtggt
      961 gccggagaaa ttccagtcca caaacggata atcggcatcc tgcttgaaca ggtcccagga
     1021 gattaaaccg ctggaatcga taaagtgcgt ttcgaggttg gtatgttcag cgacttcttc
     1081 atcatcgaag gttggcggag taaacacatc caaatctttc aggccacgac cttgcagcag
     1141 ctcggtcacg gtacgttcca gtgctacgcc aaaatcagga tgcgcaccga aagaggcaaa
     1201 gcaggtaccg ttagcaggat tgaacagtac cacgcaaatc accggatact ggccgccaag
     1261 cgaaccgtca taagcgaaga ttgggaaacc ctccgcttcc agcgtttcga tggcttcaac
     1321 tactgctggg taacgcgcca gcacgtctgc cgggatctct ggcaggctga tgctttcagc
     1381 aataatgcgg tttttcacgt agcgttcgaa aacttcagac aatccctgaa cgcgtgcttc
     1441 gttgcgggta ttacctgcgg acataccgtt ggagacgtac aggttaccaa tgatattcat
     1501 cggaatataa acggtctgat tgtcggactg acgcgtaaac ggcaggccgc aaataccacg
     1561 atcttcgtta ccggattgta ggtcaatcag catgctgccg gtcagttcat tctccggatc
     1621 ataaaacgcg cgcagacggt catcgagtag tccttctggc acatcgtcat tttcggtcag
     1681 tgggaaccat ttttcgttgg gataatgcac gaacggaccg ttggcgatgg tttcgcccag
     1741 ccagaaatca gcaaaaaagt agttggttga gagacgctcg aaatattcac caagtgcaga
     1801 agccagcgcc gcttttttgg ttgcgccttt accgttggta aaacacagtg cgcactcttt
     1861 gtcgcgaata tgtacagacc agacgttagg cacaggattc agccaggagg cctcttcaat
     1921 ctgaaagccg aggtctgaaa gtttttgctg gaagcgagcg atggaatctt ccagagcggc
     1981 atctttgccg gggataaatg tttgcgtcat gaaaatcact ttagtcgtac ggaaagcgcg
     2041 caataatacg ggttttatct caaaggcgct atcaccgccg ccatgccgat gaactgttga
     2101 ctatgctttt agcggataaa ccacgataag agcataaaaa tgaaggcgtt cgatctccac
     2161 cgtatggcat ttgataaagt gccttttgat ttccttggcg aagttgcact acgtagtctt
     2221 tatacctttg tactggtttt tctgttcctc aaaatgaccg gaagacgcgg tgtgcgacag
     2281 atgtcgctgt ttgaagtgtt aatcattctc acgctgggtt cagcggcggg agatgtggcg
     2341 ttttatgatg atgtgccgat ggtgccggta cttatcgtct ttatcactct ggcgttgtta
     2401 taccgcctgg taatgtggtt gatggcgcac agtgaaaaac tggaagattt actggaaggt
     2461 aagccggttg ttattattga agatggcgag ctggcctggt cgaaactcaa taactccaac
     2521 atgacggaat ttgagttctt tatggagcta cgattgcgtg gcgtggagca gctggggcag
     2581 gtacgtctgg cgattctcga aaccaacggg caaatcagtg tctatttctt tgaagatgac
     2641 aaggtgaaac cgggtttact tattttaccc agtgattgta cgcagcgtta caaagtggtg
     2701 ccggagtcgg cggactatgc ctgtattcgt tgtagtgaaa tcattcatat gaaagcgggg
     2761 gaaaaacaat tatgtccgcg ctgtgcaaat ccagaatgga cgaaggcaag tcgggcaaaa
     2821 cgggtgacct gacagtaaaa acatcggctt tttgctaata atccgagaga ttcttttgtg
     2881 tgatgcaagc cacatttttg ccctcaacgg ttttactcat tgcgatgtgt gtcactgaat
     2941 gataaaaccg atagccacag gaataatgta ttacctgtgg tcgcaatcga ttgaccgcgg
     3001 gttaatagca acgcaacgtg gtgaggggaa atggctcaaa tcttcaattt tagttctggt
     3061 ccggcaatgc taccggcaga ggtgcttaaa caggctcaac aggaactgcg cgactggaac
     3121 ggtcttggta cgtcggtgat ggaagtgagt caccgtggca aagagttcat tcaggttgca
     3181 gaggaagccg agaaggattt tcgcgatctt cttaatgtcc cctccaacta caaggtatta
     3241 ttctgccatg gcggtggtcg cggtcagttt gctgcggtac cgctgaatat tctcggtgat
     3301 aaaaccaccg cagattatgt tgatgccggt tactgggcgg caagtgccat taaagaagcg
     3361 aaaaaatact gcacgcctaa tgtctttgac gccaaagtga ctgttgatgg tctgcgcgcg
     3421 gttaagccaa tgcgtgaatg gcaactctct gataatgctg cttatatgca ttactgcccg
     3481 aatgaaacca tcgacggtat cgccatcgac gaaacgccag acttcggcaa agatgtggtg
     3541 gtcgccgccg acttctcttc aaccattctt tcccgtccga ttgacgtcag ccgttatggc
     3601 gtgatttacg ctggcgcgca gaaaaatatc ggcccggctg gcctgacaat cgtcatcgtt
     3661 cgtgaagatt tgctgggcaa agcgaatatc gcgtgtccgt cgattctgga ttattccatc
     3721 ctcaacgata acggctccat gtttaacacg ccgccgacat ttgcctggta tctatctggt
     3781 ctggtcttta aatggctgaa agcgaacggc ggtgtagctg aaatggataa aatcaatcag
     3841 caaaaagcag aactgctata tggggtgatt gataacagcg atttctaccg caatgacgtg
     3901 gcgaaagcta accgttcgcg gatgaacgtg ccgttccagt tggcggacag tgcgcttgac
     3961 aaattgttcc ttgaagagtc ttttgctgct ggccttcatg cactgaaagg tcaccgtgtg
     4021 gtcggcggaa tgcgcgcttc tatttataac gccatgccgc tggaaggcgt taaagcgctg
     4081 acagacttca tggttgagtt cgaacgccgt cacggttaat gccgaaattt tgcttaatcc
     4141 ccacagccag cctgtggggt ttttatttct gttgtagaga gttgagttca tggaatccct
     4201 gacgttacaa cccatcgcta gtgtcgatgg cactattaat ctgcccggtt ccaagagcgt
     4261 ttctaaccgc gctttattgc tggcggcatt agcacacggc aaaacagtat taaccaatct
     4321 gctggatagc gatgacgtgc gccatatgct gaatgcatta acagcgttag gggtaagcta
     4381 tacgctttca gccgatcgta cgcgttgcga aattatcggt aacggcggtc cattacacgc
     4441 agaaggtgcc ctggagttgt tcctcggtaa cgccggaacg gcaatgcgtc cgctggcggc
     4501 agctctttgt ctgggtagca atgatattgt gctgaccggt gagccgcgta tgaaagaacg
     4561 cccgattggt catctggtgg atgcgctgcg cctgggcggg gcgaagatca cttacctgga
     4621 acaagaaaat tatccgccgt tgcgtttaca gggcggcttt actggcggca acgttgacgt
     4681 tgatggctcc gtttccagcc aattcctcac cgcactgtta atgactgcgc ctcttgcgcc
     4741 ggaagatacg gtgattcgta ttaaaggcga tctggtttct aaaccttata tcgacatcac
     4801 actcaatctg atgaagacgt ttggtgttga aattgaaaat cagcactatc aacaatttgt
     4861 cgtaaaaggc gggcagtctt atcagtctcc gggtacttat ttggtcgaag gcgatgcatc
     4921 ttcggcttct tactttctgg cagcagcagc aatcaaaggc ggcactgtaa aagtgaccgg
     4981 tattggacgt aacagtatgc agggtgatat tcgctttgct gatgtgctgg aaaaaatggg
     5041 cgcgaccatt tgctggggcg atgattatat ttcctgcacg cgtggtgaac tgaacgctat
     5101 tgatatggat atgaaccata ttcctgatgc ggcgatgacc attgccacgg cggcgttatt
     5161 tgcaaaaggc accaccacgc tgcgcaatat ctataactgg cgtgttaaag agaccgatcg
     5221 cctgtttgcg atggcaacag aactgcgtaa agtcggtgcg gaagtagaag aggggcacga
     5281 ttacattcgt atcactccac cggaaaaact gaactttgcc gagatcgcga catacaatga
     5341 tcaccggatg gcgatgtgtt tctcgctggt ggcgttgtca gatacaccag tgacgattct
     5401 tgatcccaaa tgtacggcca aaacatttcc ggattatttc gagcagttgg cgcggattag
     5461 ccaggcagcc tgaatgaaca acgggcaata aatagccaaa tctttcttta tcaaaacgtc
     5521 ggcacattgt cggcgttttt tttcggacct tgtgagtcat tttgattaat ggtagcgtcg
     5581 cttgtcaatg taagttgttg atacataata tttatatatg attaatcaac ggatgattca
     5641 catgaagaat actaaattac tgctggcgat tgcgacctct gcagcattac tgacagggtg
     5701 tcaaaatacc cacggtattg ataccaatat ggctatcagc tccggtttaa atgcctataa
     5761 agcagcaaca ttaagcgatg ccgatgcaaa agcgattgcc aatcagggct gtgccgaaat
     5821 ggacagcggc aatcaagtcg caagtaaatc cagcaagtac ggtaaacgtc tggcaaaaat
     5881 cgccaaagca ttgggtaaca atattaatgg cacgccggtc aactataagg tttatatgac
     5941 cagcgacgtc aacgcatggg cgatggcgaa cggctgtgtc cgtgtctaca gtggcctgat
     6001 ggacatgatg aatgacaacg aaattgaagg tgttctgggc catgaactgg gccacgtcgc
     6061 gttgggtcac tcgctggctg aaatgaaagc ttcttatgcg atcgttgccg cacgcgatgc
     6121 catttcagct accagcggag tggcttccca gctttcccgc tcacaattgg gtgatatcgc
     6181 agaaggcgct attaatgcta aatactcccg tgataaagag tccgaagcag atgatttctc
     6241 ctttgatctg ttgaagaaac gtggcatcag cacccagggg ctggttggca gctttgaaaa
     6301 actggctagt ctggatggcg gtcgcaccca gtccatgttt gactctcacc caccatcaac
     6361 agagcgtgcg caacacatcc gtgatcgtat cgcctctggt aagtaaatca ttgtcatctt
     6421 tcgggctggt cttctgccag cccgctataa ttgcgcaata aatccccatc tgaatacaga
     6481 caaaactggt ttttgcacac aacgttaacg atttgtggcg tcggcgcgta taatgcgcgc
     6541 ggttatgtta acggtacgcc tgttttaagg agataaagat gacggcaatt gccccggtta
     6601 ttaccattga tggcccaagc ggtgcaggga aaggcacctt gtgtaaggct atggcggaag
     6661 cattgcaatg gcatctgctg gattcgggtg caatttatcg cgtactggca ttggcggcat
     6721 tacatcacca tgttgatgtt gcgtcagaag atgcgctggt accgctggca tcccatctgg
     6781 atgtacgttt tgtgtcaacc aatggcaatc tggaagtgat cctcgaaggg gaagatgtca
     6841 gcggcgaaat tcgtactcag gaagtggcga atgcagcttc acaagtcgcg gcattcccac
     6901 gcgttcgtga agcattattg cgtcgccaac gcgcgtttcg cgaattacca ggcctgattg
     6961 ccgatggccg cgacatggga acggtggtat tccctgatgc gccagtgaaa attttccttg
     7021 acgcctcctc ggaagaacgt gcgcatcgcc gcatgctaca gttgcaggag aagggcttta
     7081 gtgttaactt tgagcgcctt ttggccgaga tcaaagaacg cgacgaccgc gatcgtaacc
     7141 gagcggtagc gccactggtt ccggcagccg atgctttagt gttggattcc accaccttaa
     7201 gcattgagca agtgattgaa aaagcgctac aatacgcgcg ccagaaattg gctctcgcat
     7261 aagcgaccga atttgcagta cccccgttgc aatggaatga cagcgggtat gttaaacaac
     7321 cccatccggc atggagccag gtggacgtta aatataaacc tgaagattaa acatgactga
     7381 atcttttgct caactctttg aagagtcctt aaaagaaatc gaaacccgcc cgggttctat
     7441 cgttcgtggc gttgttgttg ctatcgacaa agacgtagta ctggttgacg ctggtctgaa
     7501 atctgagtcc gccatcccgg ctgagcagtt caaaaacgcc cagggcgagc tggaaatcca
     7561 ggtaggtgac gaagttgacg ttgctctgga cgcagtagaa gacggcttcg gtgaaactct
     7621 gctgtcccgt gagaaagcta aacgtcacga agcctggatc acgctggaaa aagcttacga
     7681 agatgctgaa actgttaccg gtgttatcaa cggcaaagtt aagggcggct tcactgttga
     7741 gctgaacggt attcgtgcgt tcctgccagg ttctctggta gacgttcgtc cggtgcgtga
     7801 cactctgcac ctggaaggca aagagcttga atttaaagta atcaagctgg atcagaagcg
     7861 caacaacgtt gttgtttctc gtcgtgccgt tatcgaatcc gaaaacagcg cagagcgcga
     7921 tcagctgctg gaaaacctgc aggaaggcat ggaagttaaa ggtatcgtta agaacctcac
     7981 tgactacggt gcattcgttg atctgggcgg cgttgacggc ctgctgcaca tcactgacat
     8041 ggcctggaaa cgcgttaagc atccgagcga aatcgtcaac gtgggcgacg aaatcactgt
     8101 taaagtgctg aagttcgacc gcgaacgtac ccgtgtatcc ctgggcctga aacagttggg
     8161 cgaagatccg tgggtagcta tcgctaaacg ttatccggaa ggtaccaaac tgactggtcg
     8221 cgtgaccaac ctgaccgact acggctgctt cgttgaaatc gaagaaggcg ttgaaggcct
     8281 ggtacacgtt tccgaaatgg attggaccaa caaaaacatc cacccgtcca aagttgttaa
     8341 cgttggcgat gtagtggaag ttatggttct ggatatcgac gaagaacgtc gtcgtatctc
     8401 cctgggtctg aaacagtgca aagctaaccc gtggcagcag ttcgcggaaa cccacaacaa
     8461 gggcgaccgt gttgaaggta aaatcaagtc tatcactgac ttcggtatct tcatcggcct
     8521 ggacggcggc atcgacggcc tggttcacct gtctgacatc tcctggaacg ttgcaggcga
     8581 agaagcagtt cgtgaataca aaaaaggcga cgaaatcgct gcagttgttc tgcaggttga
     8641 cgcagaacgt gaacgtatct ccctgggcgt taaacagctc gcagaagatc cgttcaacaa
     8701 ctgggttgct ctgaacaaga aaggcgctat cgtaaccggt aaagtaactg cagttgacgc
     8761 taaaggcgca accgtagaac tggctgacgg cgttgaaggt tacctgcgtg cttctgaagc
     8821 atcccgtgac cgcgttgaag acgctaccct ggttctgagc gttggcgacg aagttgaagc
     8881 taaattcacc ggcgttgatc gtaaaaaccg cgcaatcagc ctgtctgttc gtgcgaaaga
     8941 cgaagctgac gagaaagatg caatcgcaac tgttaacaaa caggaagatg caaacttctc
     9001 caacaacgca atggctgaag ctttcaaagc agctaaaggc gagtaattct ctgactcttc
     9061 gggattttta ttccgaagtt tgttgagttt acttgacaga ttgcaggttt cgtcctgtaa
     9121 tcaagcacta agggcggcta cggccgccct taatcaatgc agcaacagca gccgcttaat
     9181 ttgcctttaa ggaaccggag gaatcatgac caagtcagaa ttgatagaaa gacttgccac
     9241 ccagcaatcg cacattcccg ccaagacggt tgaagatgca gtaaaagaga tgctggagca
     9301 tatggcctcg actcttgcgc agggcgagcg tattgaaatc cgcggtttcg gcagtttctc
     9361 tttgcactac cgcgcaccac gtaccggacg taatccgaag actggcgata aagtagaact
     9421 ggaaggaaaa tacgttcctc actttaaacc tggtaaagaa ctgcgcgatc gcgccaatat
     9481 ttacggttaa gtttttactc aaacttgaac gcgagaaaag cacctgtcgg gtgctttttt
     9541 catttctcta atcaggaact ggaagctgcc tcgcagagtt ttgagcagtt ttcacccttt
     9601 cgttaaattc ttctgaatgt gcctcgggga acgcaaaatt cccaccagac aaccgctcaa
     9661 caaagttgca cactttccat aaacagggag gggggcatga aaataacgac agtcggcgta
     9721 tgcataattt gcggaatttt tccgttgctg attttgcccc aattgcctgg gacattaacc
     9781 cttgcgtttc tgactctctt cgcctgcgta ctggcattta tccctgttaa aaccgtccgt
     9841 tatatcgcgc tgacgttgct gtttttcgtt tggggcatat tatcagcaaa gcaaattttg
     9901 tgggcaggag aaaccttaac tggcgcgacg caggatgcaa ttgttgagat cactgcaact
     9961 gacggcatga ccactcatta cggtcaaatt actcatctac aaggtcgacg tatattccct
    10021 gcgccaggcc ttgtgctgta tggcgaatat cttccgcaag cggtttgtgc tggacaacaa
    10081 tggtcaatga aactcaaagt tcgtgcggtt catggccaac ttaatgatgg cggctttgat
    10141 agccagcgtt atgccattgc ccagcatcaa ccgctcaccg gccgctttct gcaggcaagt
    10201 gttattgaac cgaattgtag cctgcgtgca cagtatctgg cgtcactaca aacaacgctg
    10261 caaccctatc cgtggaatgc ggttattctt ggtttaggta tgggggaacg gttatccgtc
    10321 cccaaagaaa tcaaaaatat catgcgcgat actggaacgg cgcatttaat ggcgatatcg
    10381 ggattgcaca tcgcttttgc ggcgttgctg gctgccggac tcattcgcag tggacaaatt
    10441 tttctgcctg ggcgctggat ccactggcaa ataccattaa ttggtgggat ctgctgtgct
    10501 gctttttatg cctggttgac gggaatgcaa cctcctgcat tgcgtaccgt ggtggcgctt
    10561 gctacgtggg gaatgcttaa gttaagtggg cgacagtgga gtggctggga tgtatggata
    10621 tgttgtctgg cggcaatttt gctgatggat cctgttgcca ttctctcgca aagtttatgg
    10681 ctctctgccg ctgcggtcgc ggcactgatt ttttggtacc agtggtttcc ctgtcctgag
    10741 tggcaactgc cgccggtatt gcgtgcagtt gtttccctca ttcatttgca actgggaatc
    10801 acactcctgc ttatgcctgt gcaaatcgtc atatttcatg gcattagtct gacctcgttt
    10861 attgcaaatc tattagcaat tcccttggtg acatttatca cggttccgtt gatcctcgcc
    10921 gcgatggttg tgcatttaag cgggccgtta atcctggagc aagggttatg gtttcttgcc
    10981 gaccggtctt tggctttact tttctggggg ttaaagagtt tgccagaagg gtggatcaac
    11041 attgctgaac gttggcaatg gctatcattt tccccatggt tcttactggt ggtatggcga
    11101 ttaaacgcct ggcgaacgtt gccagcaatg tgtgtggctg taggcttgct gatgtgctgg
    11161 ccgctgtggc aaaaacctcg acctgacgag tggcaggtgt acatgcttga tgtcgggcaa
    11221 gggctggcaa tggtgatagc cagaaacggc aaagcgattc tctatgacac aggactggcc
    11281 tggcccgaag gggatagtgg gcaacaactg attatcccct ggctccactg gcataatctt
    11341 gaaccggaag gcgttattct gagtcatgaa catctggatc accggggagg gctggactca
    11401 atattgcaca catggccgat gttatggatc agaagtccgt taaactggga acatcatcag
    11461 ccctgtgtgc gtggcgaagc gtggcaatgg caaggattgc gtttcagcgt gcactggcct
    11521 ttacaagcta gcaacgataa aggaaataac cattcctgtg tggttaaggt tgatgacggg
    11581 acgaatagca ttcttctaac cggtgatatt gaagtccccg ctgaacaaaa gatgctaagc
    11641 cgttactggc agcaagtgca gacaacattg cttcaggtac ctcaccatgg cagtaatacc
    11701 tcatcatcgt tgccattaat tcagcgagtg aatggaaaag tggcactcgc atcggcatcg
    11761 cgctataacg catggcgatt gccctctaat aaagttaagc atcgctatca acagcaagga
    11821 tatcaatggc ttgatactcc acatcagggt caagtgacgg tcaatttttc agcgcaaggc
    11881 tggcggatta gcagcctcag agagcaaatt ttacctcgtt ggtatcatca gtggtttggc
    11941 gtgccagtgg ataacgggta gaatatgcgg ctatttcaac aaatgctggt tttttgaatg
    12001 cataacgaca aagatctctc tacgtggcag acgttccgcc gactgtggcc aaccattgcg
    12061 ccttttaaag cgggtctgat cgtggcgggc gtagcgttaa tcctcaacgc agccagcgat
    12121 accttcatgt tatcgctcct taagccactt cttgatgatg gctttggtaa aacagatcgc
    12181 tccgtgctgg tgtggatgcc gctggtggtg atcgggctga tgattttacg tggtatcacc
    12241 agctatgtct ccagctactg tatctcctgg gtatcaggaa aggtggtaat gaccatgcgt
    12301 cgccgcctgt ttggtcacat gatgggaatg ccggtttcat tttttgacaa acagtcaacg
    12361 gggacgctgt tgtcacgtat cacctacgat tccgaacagg ttgcttcttc ttcttccggc
    12421 gcactgataa cggttgtgcg tgaaggtgcg tcaatcatcg gcctgttcat catgatgttc
    12481 tattacagtt ggcaactgtc gatcattttg attgtgctgg caccgattgt ttcgattgcg
    12541 attcgcgtag tatcgaagcg ttttcgcaac atcagtaaaa acatgcagaa caccatgggg
    12601 caggtgacca ccagcgccga acaaatgctg aagggccaca aagaagtatt gattttcggt
    12661 ggtcaggaag tggaaacgaa acgctttgat aaagtcagca accgaatgcg tcttcagggg
    12721 atgaaaatgg tttcagcctc ttccatctct gatccgatca ttcagctgat cgcctctttg
    12781 gcgctggcgt ttgttctgta tgcggcgagc ttcccaagtg tcatggatag cctgactgcc
    12841 ggtacgatta ccgttgtttt ctcttcaatg attgcactga tgcgtccgct gaaatcgctg
    12901 accaacgtta acgcccagtt ccagcgcggt atggcggctt gtcagacgct gtttaccatt
    12961 ctggacagtg agcaggagaa agatgaaggt aagcgcgtga tcgagcgtgc gactggcgac
    13021 gtggaattcc gcaatgtcac ctttacttat ccgggacgtg acgtacctgc attgcgtaac
    13081 atcaacctga aaattccggc agggaagacg gttgctctgg ttggacgctc tggttcgggt
    13141 aaatcaacca tcgccagcct gatcacgcgt ttttacgata ttgatgaagg cgaaatcctg
    13201 atggatggtc acgatctgcg cgagtatacc ctggcgtcgt tacgtaacca ggttgctctg
    13261 gtgtcgcaga atgtccatct gtttaacgat acggttgcta acaacattgc ttacgcacgg
    13321 actgaacagt acagccgtga gcaaattgaa gaagcggcgc gtatggccta cgccatggac
    13381 ttcatcaata agatggataa cggtctcgat acagtgattg gtgaaaacgg cgtgctgctc
    13441 tctggcggtc agcgtcagcg tattgctatc gctcgagcct tgctgcgtga tagcccgatt
    13501 ctgattctgg atgaagctac ctcggctctg gataccgaat ccgaacgtgc gattcaggcg
    13561 gcactggatg agttgcagaa aaaccgtacc tctctggtga ttgcccaccg cttgtctacc
    13621 attgaaaagg cagacgaaat cgtggtcgtc gaggatggtg tcattgtgga acgcggtacg
    13681 cataacgatt tgcttgagca ccgcggcgtt tacgcgcaac ttcacaaaat gcagtttggc
    13741 caatgatcga aaaaatctgg tctggtgaat cccctttgtg gcggctattg ctgccactct
    13801 cctggttgta tggcctggta agtggcgcga tccgtctttg ctataaacta aaactgaagc
    13861 gcgcctggcg tgcccccgta ccggttgtcg tggttggtaa tctcaccgca ggcggcaacg
    13921 gaaaaacccc ggtcgttgtc tggctggtgg aacagttgca acagcgcggt attcgcgtgg
    13981 gggtcgtatc gcggggatat ggtggtaagg ctgaatctta tccgctgtta ttgtcggcag
    14041 ataccacaac agcacaggcg ggtgatgaac ctgtgttgat ttatcaacgc actgatgcgc
    14101 ctgttgcggt ttctcccgtt cgttctgatg cggtaaaagc cattctggcg caacaccctg
    14161 atgtgcagat catcgtaacc gacgacggtt tacagcatta ccgtctggcg cgtgatgtgg
    14221 aaattgtcgt tattgatggt gtgcgtcgct ttggcaatgg ctggtggttg ccggcggggc
    14281 caatgcgtga gcgagcgggg cgcttaaagt cggttgatgc ggtaatcgtc aacggtggtg
    14341 tccctcgcag cggtgaaatc cccatgcatc tgctgccggg tcaggcggtg aatttacgta
    14401 ccggtacgcg ttgtgacgtt gctcagcttg aacatgtagt ggcgatggcg gggattgggc
    14461 atccgccgcg cttttttgcc acgctgaaga tgtgtggcgt acaaccggaa aaatgtgtac
    14521 cgctggccga tcatcagtct ttgaaccatg cggatgtcag tgcgttggta agcgccgggc
    14581 aaacgctggt aatgactgaa aaagatgcgg tgaaatgccg ggcctttgca gaagaaaatt
    14641 ggtggtattt gcctgtagac gcacagcttt caggtgatga accagcgaaa ctgcttacgc
    14701 aactaacctc gctggcttct ggcaactagt tacgccgcgg cagcgttcga ttgatggagt
    14761 catgaatgtc gctgccgcac ctctcccttg ctgatgcgcg taatcttcac cttgccgcac
    14821 aaggcctgtt aaacaaaccc cgccgtcaag cgtcgttgga ggatattccg gcaacgatct
    14881 cccgcatgtc cttgctgcaa atcgatacca tcaatattgt tgcccgtagt ccatatctgg
    14941 tgcttttcag tcgtctggga aattatcctg cccagtggct ggatgagtct ctggcgcgtg
    15001 gcgaattaat ggaatactgg gcgcatgaag cctgctttat gccgcgtagc gactttcgtc
    15061 ttattcgcca ccgcatgctg gcacctgaaa aaatgggctg gaaatacaaa gacgcctgga
    15121 tgcaggaaca tgaggcggaa attgcacagt taattcagca tattcatgat aaggggccgg
    15181 tacgttcagc cgattttgag catcctcgta aaggtgcaag cggctggtgg gaatggaagc
    15241 cgcataaacg gcatctggaa ggtttattta ctgccggaaa ggtgatggtg attgaacggc
    15301 gcaacttcca gcgcgtttat gatttaaccc accgtgtcat gcctgactgg gatgatgagc
    15361 gcgatctcgt ttcgcaaaca gaagcagaaa tcatcatgct ggataacagt gcgcgtagcc
    15421 tgggaatatt ccgcgaacag tggctggcag attactatcg gctgaaacgt ccggcactgg
    15481 cggcgtggcg cgaagcgagg gctgaacagc agcaaatcat tgctgtgcat gttgaaaaat
    15541 tgggcaatct ttggctgcat gctgatttgc tgccgctact cgagcgtgcg ctggccggaa
    15601 agctcactgc aacgcacagc gcggtacttt cgccttttga tcctgttgtc tgggatcgca
    15661 aacgcgcaga gcagcttttt gattttagct accggctgga gtgctatacc ccagcgccga
    15721 aacgccagta tggctatttt gttctgccat tattacatcg tgggcaatta gttgggcgaa
    15781 tggatgccaa aatgcatcgc cagacaggca tccttgaagt tatctctctg tggttacagg
    15841 aaggcattaa accaacgaca atgctgcaaa aagggttacg tcaggcgatt actgatttcg
    15901 cgagctggca gcaggcaacg cgggtgacat taggacgctg cccgcaaggt ctctttactg
    15961 attgccgcac tggctgggaa atagaccccg tcgcataaat gattatgata agatttatgc
    16021 attcataacc cgatccatct ggaggaacta tggatcatcg tctgcttgaa atcattgcct
    16081 gcccggtttg caacggaaaa ctttggtata accaagaaaa acaagaactt atttgcaaac
    16141 tggacaacct ggctttcccg ctgcgtgatg gcattccagt gttgctggaa acggaagccc
    16201 gcgtgctgac tgctgatgag agtaaatcat gagttttgtg gtcattattc ccgcgcgcta
    16261 cgcgtcaacg cgtctgcccg gtaaaccatt ggttgatatt aatggcaaac ccatgattgt
    16321 tcatgttctt gaacgtgctc gcgaatcagg tgccgatcgc atcatcgtgg caaccgatca
    16381 tgaggatgtc gcccgcgccg ttgaagccgc tggcggtgaa gtatgtatga cgcgcgccga
    16441 tcaccagtca gggacagaac gcctggcgga agttgtcgaa aaatgcgcat tcagcgacga
    16501 cacggtgatc gttaatgtgc agggtgatga accgatgatc cctgcgacaa tcattcgtca
    16561 ggttgctgat aacctcgctc agcgtcaggt gggtatggcg actctggcgg tgccaatcca
    16621 caatgcggaa gaagcgttta acccgaatgc ggtgaaagtg gttctcgacg ctgaagggta
    16681 tgcactgtac ttctctcgcg ccaccattcc ttgggatcgt gatcgttttg cagaaggcct
    16741 tgaaaccgtt ggcgataact tcctgcgtca tcttggtatt tatggctacc gtgcaggctt
    16801 tatccgtcgt tacgtcaact ggcagccaag tccgttagaa cacatcgaaa tgttagagca
    16861 gcttcgtgtt ctgtggtacg gcgaaaaaat ccatgttgct gttgctcagg aagttcctgg
    16921 cacaggtgtg gatacccctg aagatcttga gcgcgttcgc gctgaaatgc gctaatttca
    16981 cttcacgaca cttcagccaa ttttgggagg agtgtcgtac cgttacgatt ttcctcaatt
    17041 tttcttttca acaattgatc tcattcaggt gacatctttt atattggcgc tcattatgaa
    17101 agcagtagct tttatgaggg taatctgaat ggaacagctg cgtgccgaat taagccattt
    17161 actgggcgaa aaactcagtc gtattgagtg cgtcaatgaa aaagcggata cggcgttgtg
    17221 ggctttgtat gacagccagg gaaacccaat gccgttaatg gcaagaagct ttagtacgcc
    17281 cggaaaagcc cgacaactgg catggaaaac caccatgctg gcaagaagtg ggactgtccg
    17341 tatgccgact atttatggtg tgatgacgca tgaagaacac cccggccccg atgtcctgct
    17401 actggagcgg atgcgtggtg tttcggtgga ggcaccagcc cgaacaccag aacgctggga
    17461 acaactcaaa gaccaaatcg ttgaagcctt actggcctgg caccgtcagg acagtcgcgg
    17521 ttgcgtcggc gcggtcgaca atactcagga aaatttctgg ccctcatggt accggcaaca
    17581 tgttgaagtg ctatggacca cgctcaatca gttcaataac accggtctga cgatgcagga
    17641 taagcggatc ctgtttcgca ctcgcgaatg tctcccggca ttatttgaag gctttaacga
    17701 caattgtgtg ctgattcacg gtaacttctg tttacgcagc atgttgaaag attcgcgcag
    17761 cgatcagtta ctggcgatgg tcgggccggg actaatgctt tgggcaccgc gagaatacga
    17821 actgttccga ctaatggata attctctggc ggaagatttg ctctggagtt acctgcaacg
    17881 cgcgccagtg gcggagtcgt tcatctggcg gcgttggttg tatgtgttat gggatgaagt
    17941 tgcgcaactg gttaataccg gacgatttag tcggcgcaac ttcgatctgg catcaaaatc
    18001 actcttgccg tggctcgcct gacgaacctt ttagccactg ccagatacgg ccaagcgttt
    18061 catagccaac acgatcgcta tgcatcaacc agaccggaga agggattgcc cgttcccacg
    18121 ggttaagcgg cgagtcgatg gccaactgat tcgccggggc tggtagcgga tttaaccctt
    18181 cctgctgaaa aaagatcatc gcccgcggca gatgtgatgc ggaggtcacc agcaggaaag
    18241 gggcgtcacc aatcgcctgt ttcactgccg cagcttcttc ttcggtatct tttggcaaat
    18301 ccagggtgat aatttgctcg tgcggcacgc ccagcgattg cgcaactctg gcacctactt
    18361 ccgctgtact caccgtattg gtttttgcta cgcctcccgt gaagatcagt tttgatcccg
    18421 gattttcgcg ccataagcga ataccttcat tcaggcgtgg cagactgtta ttgattaaat
    18481 tagagctcgg tgcccactgt gggttccagg tataaccacc tccgagcacc acgatatagt
    18541 ccactttttg cgaattattc catgtcggat aggtgctttc gatgggacgc agcaggcggt
    18601 cggctaccgg ttgcaaactc aataacaaga gtgccagcca cccaatgcta ataaaaatct
    18661 tcccggtttt ttgaaaacgg ctaaaccaca gcagcgccag gccagcgcca ataattaaca
    18721 acatcagcgg aagtggcagc aacatattgc caatcacttt tttcagtgta aaaagcatcc
    18781 tttctggttc cttttttaac catatagcaa gggatcgcca gcgatattac accagacggg
    18841 ttcattctcg ccgtggctgt gacaaaatag cgtctttatc agaaaacgtc ttagccaacc
    18901 ggtggagaaa gcaatgcagg atcgcaattt tgatgatatt gcggaaaagt tttcccgtaa
    18961 catttacggc accaccaaag ggcagcttcg acaggctatt ctgtggcagg atctcgatca
    19021 cgtgctggcg gaaatgggcc cgcaaaaact gcgtgtgctg gatgctggcg gtggtgaagg
    19081 gcagaccgca atcaaaatgg ccgagcgtgg gcatcaggtc attttatgcg atctttctgc
    19141 gcagatgatc gaccgcgcaa aacaggcggc agaagcaaaa ggtgtgagcg acaacatgca
    19201 atttatacat tgcgccgctc aggatgttgc ttcgcatttg gaaacgcccg ttgatctgat
    19261 attgttccat gcggtgctcg agtgggtggc cgatccccgc agtgtattgc agaccctgtg
    19321 gtcagtgttg cgtccaggcg gcgtgttgtc gttaatgttc tacaatgcgc atggtttgtt
    19381 gatgcataac atggtcgccg ggaattttga ttacgtgcag gcgggaatgc cgaaaaagaa
    19441 aaaacggacg ctttcgccag attatccacg cgacccggcg caggtttatc tgtggctgga
    19501 agaagctggt tggcaaatta tgggtaagac aggcgttcgc gtgtttcatg attatctgcg
    19561 cgagaagcac cagcagcgcg actgctatga agcattactt gaattagaaa cgcgttattg
    19621 ccgtcaggaa ccgtatatta ccctggggcg ttatattcat gtcaccgcgc gcaaaccgca
    19681 gagcaaggat aaagtatgag tgaattttcc cagacagtcc ccgaactggt tgcctgggcc
    19741 agaaaaaatg acttctccat ctcgctgccg gtagaccgac tctcttttct gctggcggtt
    19801 gccacgctga acggcgagcg tctggatggt gagatgagtg aaggcgagct ggtggatgca
    19861 ttccgccatg tgagtgatgc gtttgagcaa accagcgaaa ccatcggcgt gcgcgccaat
    19921 aacgcgatca acgacatggt gcgtcaacgt ctgctgaacc gctttaccag cgagcaggcg
    19981 gaagggaacg caatttaccg tctgacgccg ctcggcatcg gcattactga ctactacatc
    20041 cgtcagcgcg agttttctac gctgcgtctt tctatgcagt tgtcgattgt ggcgggtgag
    20101 ctcaaacgcg cagcagatgc cgccgaagag ggcggtgatg aatttcactg gcaccgtaat
    20161 gtctatgcgc cactgaaata ttcggtagca gaaattttcg acagtatcga cctgacgcaa
    20221 cgtctgatgg acgaacagca gcagcaggtg aaggacgata tcgcccagtt gctgaacaaa
    20281 gactggcggg cggcgatttc cagctgtgaa ttgttgcttt cggaaacttc cgggacgctg
    20341 cgtgaattgc aggatacgct ggaagcggca ggcgacaaat tgcaggctaa tctgttgcgc
    20401 attcaggatg cgacgatgac ccatgacgat ctgcatttcg tcgatcgtct ggtgttcgat
    20461 ctgcagagca aactcgatcg tattatcagt tggggccagc aatccatcga cttgtggatt
    20521 ggctacgacc gccacgtaca caaatttatt cgtaccgcga tcgatatgga taaaaaccgc
    20581 gtctttgctc agcggttacg tcagtcggta caaacctatt ttgatgagcc gtgggcgcta
    20641 acttatgcca atgccgatcg tctgctggat atgcgtgacg aagagatggc actgcgcgat
    20701 gaagaagtga ctggggaact tcctgaggat ctggaatacg aagagtttaa cgagatccgc
    20761 gaacagctgg cggcgatcat cgaagaacaa cttgccgtgt acaaaaccag acaagtgccg
    20821 ctggatcttg gtctggtggt acgcgaatat ctgtcacagt atccgcgtgc acgtcacttt
    20881 gacgttgcgc gtattgttat tgatcaggcg gtacgtcttg gcgtagcgca agcagatttc
    20941 accggactgc cagcgaaatg gcagccgatt aatgattacg gagccaaggt acaggcgcat
    21001 gtcatcgaca aatattgaac aagtgatgcc ggttaagctg gcgcaggcgc tggcgaatcc
    21061 gttatttccg gcgctggaca gcgccttacg ttcaggccgc catattggcc tcgacgaact
    21121 ggataatcat gcattcctga tggattttca ggaatatctg gaagagtttt acgcgcgtta
    21181 taacgttgag cttattcgcg caccagaagg gttcttctat ttacgcccac gttccaccac
    21241 gctgatccct cgttccgtct tgtcggaact ggatatgatg gtcgggaaaa tcctctgtta
    21301 tctctatctc agcccggaac ggctggcgaa tgaggggatt ttcacccagc aggaactgta
    21361 cgacgaactg ctcaccctgg ccgatgaagc aaaactgctg aaactggtga acaaccgttc
    21421 aaccggttca gacgttgacc gtcagaagtt gcaggagaaa gtacgttctt cgctcaaccg
    21481 tctgcgtcgt ttaggcatgg tgtggtttat gggccacgac agcagcaagt ttcgcattac
    21541 cgaatcggtg ttccgcttcg gagccgatgt gcgtgctggc gacgatcccc gtgaagcaca
    21601 gcgtcgcctg attcgtgatg gcgaagcaat gccgattgaa aatcatctgc aactcaacga
    21661 tgaaaccgaa gaaaatcagc cagatagcgg agaggaagaa taatgattga acgcggtaaa
    21721 tttcgctcac tgacgctgat taactggaac ggcttttttg cccgaacttt tgaccttgac
    21781 gagctggtca cgacgctttc tggcggtaac ggggcgggta aatccaccac catggcggcg
    21841 ttcgttacgg cgctgatccc cgacctgacc ctgctgcatt tccgtaacac tacggaagcc
    21901 ggggccacca gcggttcgcg cgataaaggt ctgcacggta agctgaaagc gggtgtctgt
    21961 tattcgatgc tcgacaccat taactcgcgc caccagcgcg tggtggtcgg tgtgcgtctg
    22021 caacaggttg ccggacgcga tcgtaaagtg gatatcaagc cgtttgccat tcagggactg
    22081 ccgatgtcgg tgcagccgac acagctggtg accgaaaccc tgaacgaacg ccaggcgcgc
    22141 gtgctgccgc ttaacgagct gaaagacaag ctcgaggcga tggaaggcgt gcagtttaaa
    22201 cagttcaact ccattactga ttaccactcg ctgatgttcg atctgggcat catcgcgcgt
    22261 cgtctgcgct ccgcatctga ccgtagcaaa ttctatcgtc tgatcgaagc ttcgctgtat
    22321 ggcgggatct ccagtgccat tacccgttct ctgcgcgact acctgttgcc ggaaaacagc
    22381 ggcgtgcgta aagcgttcca ggacatggaa gcggcgctgc gtgaaaaccg tatgacgctg
    22441 gaagcgattc gtgtcaccca gtcggaccgt gacctgttta agcatctgat cagcgaagct
    22501 accaactacg tggcggcgga ctacatgcgt cacgccaacg agcgccgtgt ccatctcgac
    22561 aaagccctgg agtttcgtcg cgagttacat acttcgcgtc agcaactggc ggctgagcag
    22621 tacaaacacg tcgatatggc gcgtgagctg gcagagcaca acggtgccga aggcgatctg
    22681 gaagcggatt atcaggcggc cagcgatcac ctgaacctgg tgcaaaccgc actgcgtcag
    22741 caggagaaga tcgaacgcta cgaagcggat ctcgatgagc tgcagatccg tctggaagag
    22801 caaaacgaag tggtggcaga agccatcgaa cgccaggaag agaacgaggc tcgcgcggaa
    22861 gctgccgaac tggaagtgga cgagctgaaa agccagcttg ctgactacca gcaggcgctg
    22921 gacgtccagc aaacgcgcgc gatccagtat aaccaggcga ttgctgcgct taatcgcgcc
    22981 aaagaactgt gccatctgcc ggacttaacc gccgacagcg ccgccgaatg gctggaaacc
    23041 ttccaggcga aagagctgga agcgactgaa aaaatgctct ctcttgagca gaaaatgagc
    23101 atggcgcaaa ccgcgcacag ccagtttgag caggcttatc agctggtggt ggcaatcaac
    23161 ggcccgctgg cgcgtaacga ggcgtgggat gtcgctcgcg aactattgcg cgaaggggtc
    23221 gatcagcgtc acctggcaga gcaggttcaa ccgttgcgga tgcgcttaag tgaactggaa
    23281 cagcgtctgc gcgagcagca agaagccgaa cgcctgctgg cagacttctg caaacgtcag
    23341 ggcaagaatt ttgatattga tgaactggaa gctctgcatc aggagctgga agcgcgcatt
    23401 gcctctcttt ccgatagcgt gtctaacgcc cgtgaagagc gcatggcact gcgccaggaa
    23461 caggaacagc tgcagtctcg cattcagagt ttgatgcagc gtgcgccggt ttggctggca
    23521 gcgcaaaaca gtctcaacca gttgagcgag cagtgcggtg aagagtttac ctccagccag
    23581 gacgtcaccg aatatctgca acagttgctg gagcgtgagc gagaggcgat tgttgaacgc
    23641 gatgaagtgg gcgcgcgcaa aaacgctgtc gatgaagaga tcgaacgttt aagccagcct
    23701 ggcggctctg aagatcagcg tctgaacgcg ctggcggagc gttttggcgg cgtgctgctg
    23761 tcagaaattt atgacgacgt tagcctggaa gatgcgccgt acttctcagc gctgtatggc
    23821 ccgtcacgcc acgccatcgt ggtgccagat ctgtcacagg taactgaaca cctggaaggc
    23881 ttgaccgatt gcccggaaga tctctatctg atcgaaggag atccgcagtc attcgatgac
    23941 agcgtgttca gcgttgatga gctggaaaaa gcggtagtgg tgaaaatcgc cgatcgtcag
    24001 tggcgttatt cacgtttccc ggaagtgccg ctgtttggtc gtgctgcgcg tgaaagccgt
    24061 attgaaagcc tccatgccga gcgtgaagtg ctttccgaac gcttcgccac gctctccttt
    24121 gatgtacaga aaactcagcg tctgcatcag gcgttcagcc gctttatcgg cagtcatctg
    24181 gcggttgcgt ttgagtctga cccggaagca gaaatccgtc aactgaacag ccgtcgcgtc
    24241 gaactggagc gggcgttgag taatcatgaa aatgataacc agcagcagcg tattcagttt
    24301 gagcaggcga aagaaggcgt tacggcgctg aaccgcattc tgccgcgtct caacctgttg
    24361 gctgatgaca gcctggcgga tcgcgtcgat gaaatccgcg aacgtctgga tgaagcccag
    24421 gaagccgcgc gttttgttca gcagtttggc aatcaactgg cgaaactgga accgatcgtt
    24481 tcggtattgc agagcgaccc ggaacagttc gaacagctaa aagaagatta cgcgtactct
    24541 cagcagatgc agcgcgatgc ccgtcagcag gcgtttgccc tgacggaagt ggcgcagcgt
    24601 cgtgcgcact ttagctattc tgactcggca gaaatgctga gcggtaatag cgatctcaac
    24661 gaaaagctgc gtgaacgtct ggaacaggcg gaagcggagc gtactcgcgc tcgtgaagcg
    24721 ttgcgtggtc acgcagcgca gttgagtcag tacaaccagg tgctggcttc gctgaaaagt
    24781 tcttacgaca ccaaaaaaga gctactcaac gatctgcaac gtgaattgca ggatatcggc
    24841 gtgcgcgccg atagcggggc agaagagcgg gcgcgaattc gccgtgacga gctgcatgcg
    24901 caactgagta ataaccggtc ccgccgcaac cagctggaaa aagcactgac tttctgcgaa
    24961 gcggagatgg acaatctgac ccgcaaactg cgcaagctgg agcgggatta ctttgagatg
    25021 cgcgagcagg tagtgaccgc caaagcgggc tggtgtgcag tgatgcgcat ggtgaaagat
    25081 aacggcgttg aacggcgctt acaccgtcgc gagctggctt atctctccgc tgatgatttg
    25141 cgctctatgt cggataaggc attgggtgcg ctgcgtctgg cggtggcgga taacgaacat
    25201 ctgcgcgacg tgctgcgcat gtcggaagat ccaaaacgtc cggaacgtaa aattcagttc
    25261 ttcgtggcgg tttatcagca tctgcgtgaa cgtattcgtc aggatattat tcgtaccgat
    25321 gatccggtgg aagccatcga gcagatggaa atcgaactta gccgactgac cgaggagtta
    25381 acctcccgcg aacagaaact ggcgatcagt tcccgcagcg tggcgaacat cattcgcaaa
    25441 accattcagc gcgagcagaa ccgtatccgt atgctcaacc aggggttgca gaacgtatcg
    25501 tttggtcagg tgaacagcgt acgtctgaac gtgaacgtgc gtgaaacgca cgccatgctg
    25561 ctggatgtgc tctctgaaca gcacgagcag catcaggatc tgtttaacag caaccgtctg
    25621 accttctcgg aagcgctggc gaaattgtat cagcgtctta atccgcagat tgatatgggg
    25681 cagcgcacgc cgcagaccat tggcgaagaa ctgctggatt accgcaacta tctggaaatg
    25741 gaagttgagg ttaatcgtgg ttccgatggc tggttgcgcg cagagtctgg tgcattgtcg
    25801 accggtgagg cgattggtac cggtatgtcg attctggtga tggtggtaca aagctgggaa
    25861 gatgaatctc gccgcctgcg cggtaaagat atctctcctt gccgcctgct gttcctcgat
    25921 gaagcagcgc gactggatgc tcgttctatc gccacgctgt ttgaattgtg tgaacgtttg
    25981 caaatgcagc tcatcatcgc agcgccggaa aatatcagcc cggagaaagg caccacctat
    26041 aaactggtgc gtaaagtctt ccagaatacc gaacacgttc acgtcgtcgg cctgcgagga
    26101 tttgcgccgc aactccctga aacgcttcca ggaagtgacg aagcgccttc tcaggcgagt
    26161 taaaattaag gcggcagcaa tgccgccttt tctttttccg aaaactccgt ttctgcacta
    26221 aaaaagtggc acattacggc gcgcttttct ttaaacttct ttacattagg ttatgtaaaa
    26281 acgtatcggc gtttatatac tgaagataag cctgatgagt aacaggcttg ctcgtcatac
    26341 tttcgtgagt attggcgttg tacaggcaag tcgtaaaata acagcctggc tattcagagt
    26401 atgataaaaa cagggggcaa gggatgttgc ttaatatgat gtgtggtcgt cggctgtcgg
    26461 caatcagttt gtgcctggcc gtaacattcg ctccactgtt caatgcgcag gccgatgagc
    26521 ctgaagtaat ccctggcgac agcccggtgg ctgtcagtga acagggcgag gcactgccgc
    26581 aggcgcaagc cacggcaata atggcgggga tccagccatt gcctgaaggt gcggcagaaa
    26641 aagcccgcac gcaaatcgaa tctcaattac ccgcaggtta caagccggtt tatcttaacc
    26701 agcttcaact gttgtatgcc gcacgcgata tgcaacccat gtgggaaaac cgtgatgctg
    26761 ttaaagcctt ccagcaacag ctggcagagg tggcgattgc cggtttccag ccgcagttta
    26821 ataaatgggt agagttactg accgatcctg gtgttaacgg gatggcacgc gacgtagtgc
    26881 tctctgatgc gatgatgggc tatctccatt tcattgcaaa tattccggtc aaaggcactc
    26941 gctggctata tagcagtaaa ccttatgcac ttgcaacgcc gccgctctcg gtgattaacc
    27001 aatggcagct ggcgctggat aaaggtcaat tgcctacgtt tgttgctgga ctggcaccgc
    27061 agcatccgca atatgcggcg atgcatgaat cgttactggc cttactcagt gacaccaaac
    27121 cgtggcccca actgaccggc aaagcaacgt tgcgcccagg gcagtggagt aacgacgtac
    27181 cggcgttgcg cgaaatattg caacgcacag gcatgttgga cggggggccg aaaattactc
    27241 tacctggcga tgacacgcca actgacgcgg tagtcagccc atccgctgtt actgttgaaa
    27301 cagcagaaac taagccgatg gacaagcaaa cgacatctcg tagtaaacct gcgcctgccg
    27361 ttcgcgccgc ctacgataat gaactggtgg aagccgttaa acgttttcag gcatggcaag
    27421 gattgggggc agatggtgct attggcccgg caacacgtga ctggttaaac gtaacgcccg
    27481 cccagcgtgc tggcgtgttg gctctcaaca tccagcgatt gcgcttgctg ccaacagagc
    27541 tttctaccgg gatcatggtt aacattccgg cctattcgct ggtctactat cagaacggca
    27601 atcaggtgct ggattcgcga gtcattgtcg gtcgccccga tcgcaaaacg ccgatgatga
    27661 gcagtgccct taacaacgta gtggtaaacc cgccgtggaa cgtacctcca actctggcac
    27721 gcaaagatat tctgccaaaa gtgcgcaacg atccgggata tctcgaaagc catggctata
    27781 cggtgatgcg cggctggaac agcagagaag cgattgaccc atggcaggtt gactggtcta
    27841 caatcacggc ctcgaattta ccgttccgct tccagcaggc tccaggccca cggaactcgc
    27901 tggggcgcta taaattcaat atgccgagtt cagaggccat ttatttgcat gacacgccga
    27961 accacaatct gttcaagcgt gatacacgcg cattgagctc aggctgtgta cgagtgaata
    28021 aagcttccga tctggcgaat atgctgttgc aggatgcagg ctggaatgac aaacgtattt
    28081 ctgatgcgct gaagcagggt gatacacgtt acgtcaatat tcggcagtcg attccggtga
    28141 atctctacta cctgacggcc tttgttggtg cagatggtcg tacccagtat cgtacagata
    28201 tttacaatta tgatctgcct gcgcgatcca gctcgcaaat cgtatcgaaa gcggaacaat
    28261 taatcaggta aatgaagtag ttcggggaaa tcagttgtcg taataattag catgattggg
    28321 ggcgattctc tgcagcctcc gtcactgctg gggttgagtc atcttgacgt ctgctttacg
    28381 ggcggttaag gtgcctcttg tgcgccagaa gtgcatataa acgataacat tgacctgtag
    28441 acttgattat catggacaaa ttcgacgcta atcgccgcaa attgctggcg cttggtggcg
    28501 ttgcactcgg tgccgccatc ctgccgaccc ctgcgtttgc aacactctct accccacgcc
    28561 cgcgcatttt gacactcaat aatcttcata ccggagagtc aatcaaagcg gagtttttcg
    28621 atggcagagg ctatattcag gaagaattgg caaaacttaa ccattttttc cgcgattacc
    28681 gcgcgaacaa aataaagtcc atcgacccag gattattcga ccagttgtat cgcctgcaag
    28741 ggttgttagg cacgcgcaaa ccggtgcaac tcatttccgg ttatcgttct attgatacca
    28801 acaatgaact acgcgcccgc agccgtggag tagcgaagaa aagctatcac actaaaggcc
    28861 aggcgatgga tttccatatt gaaggtatcg cgttaagcaa tattcgcaaa gccgcgttat
    28921 ctatgcgcgc aggtggtgta ggatattatc cacgtagtaa ctttgtgcat attgataccg
    28981 ggccagcacg gcactggtag taattgctta acgaaacagg ggcagtatga actatcgtat
    29041 tattccggtc accgcattct cccagaactg ttcattaatc tggtgtgaac aaacccgtct
    29101 ggccgcactg gtcgatcctg gcggcgatgc ggaaaaaatc aaacaggaag ttgatgacag
    29161 cggcctgaca ctgatgcaga tcctgctgac gcatggtcat ctggaccacg ttggcgcagc
    29221 ggcggaactg gcgcaacatt acggcgtgcc ggtttttggc ccggaaaaag aagatgagtt
    29281 ctggctgcaa ggcttgcctg cgcaaagtcg tatgtttggt ctggaagagt gccagccgct
    29341 gacgccagat cgttggctga acgaaggcga taccatcagc atagggaatg tgactttaca
    29401 ggtgttacat tgccctgggc atacgccggg tcatgtcgtg ttttttgatg atcgggcaaa
    29461 gctgctgatt tctggcgatg ttattttcaa aggcggagta gggcgcagtg acttcccgcg
    29521 tggcgatcat aatcaactga tttcttcaat caaagataaa ttgctgccac tgggggatga
    29581 cgttacattt attccgggtc acggaccatt atccacactt ggttatgaac gcctgcataa
    29641 tcccttcctg caagacgaaa tgcccgtctg gtaaggcaca taaaaaagcc cgcttttaat
    29701 gcgggcctgg atttctggca aagtgcgctt tgtttatgcc ggatgcggca cgagcgcctt
    29761 atccggccta caaaatcgtg caaattcaaa atattgcagg ggacgcgtag gcctgataag
    29821 cgtagcgcat caggcaatgt tgcgtttgtc atcagtctca gcccgctttt cagcgggctt
    29881 cattgttttt aatgcttaca gcactgccac aatcgcttcg cacagcggag ccatgttatc
    29941 tggtgtcatc ccggccacat ttacgcgacc agaagcaacc gcatatacgc caaactcttc
    30001 gcgcagacgc agcacttgtt cttttgtcag gccactgaag gagaacatgc cgttctgttt
    30061 gatgataaag ctgaagtcgc ggtttgcgcc tttttcctgc agcgtattga cgaacaactg
    30121 acgcatacgc tgaatacgct ggcgcatatc agtcagctct tgttcccaaa tcgcacgtaa
    30181 cgcatcgttg ctcaggatgg tggcaacaac agaagcgccg tgtgctggtg ggttagagta
    30241 gttagcgcga atcgccgctt tcatttggct gaatgcgcga tcaacggttt cactgtcggc
    30301 agcaaccaga gtacaagcgc caacacgctc gttgtacagg ccaaagtttt tagagtagga
    30361 actggcaaca atcagctctt tatgcatagc cgcgaaagcg cgcagtcctt cagcatcttc
    30421 ttccagacca cgggcaaaac cctggtaagc gaagtcaaac agcggtaacc agcctttctc
    30481 aactgagagt tgtgccagtg tctgccattg ttccagcgta gggtcgatac cggttgggtt
    30541 atggcagcag ccatggaaca gcactacgtc gccagcctga gcttcattca ggctgttaat
    30601 cagtgcatcg aagtcaagag tgtgattttc cgcatcataa taagcgtatt cacgaacttc
    30661 cagacctgca gagttaaaga cgctcttatg gttcggccag cttgggttgc tcacccacac
    30721 tcgcttaacg ctggtatttt ttgccaggaa atcggcagct acgcgtagtg cgccagtgcc
    30781 ccccggagtc tgtgccgtgc gagcacgttt gtcattgatc agggcgctac ctttaccaaa
    30841 cagcagttcc tgagtgcagc gaccaaattc agggatgccg tcaatgccga ggtaattttt
    30901 ggtggtttca ttttcgagca gatactgttc agcctttttc acgctggtca gtaccggggt
    30961 tttgcccgtc tcatctttat agacaccaat cccgaggtta attttgccgg gacgttcatc
    31021 ggcacgaaac agatcggcca ggcccagaat cgggtcggca ggagcggcgg taatgttctc
    31081 aaacatgacg aggttccatt atggttacag aagggaagtc cgctatcagg gtaacgggag
    31141 atttacaaaa ttccaactat tactgatgaa aacgcaggct gtttttgcaa gacgtgagat
    31201 tgctctggaa ggtataaaaa aaacaggacc aaagtcctgt tttttcggca tttaacaaag
    31261 aggtgtgcta ttagaactgg taaacgatac ccacagcaac ggtgtcgtct gaacctacgc
    31321 ccagtttgtt gtcagaatcg atctggttga tgatgtagtc aacataggtg gacatgtttt
    31381 tgttgaagta gtaggttgcg cccacttcaa agtagttcac cagatcaaca tcaccgatac
    31441 cttctacgtc tttcgcttta gatttggtgt aagcgatgga cggacgcaga ccgaaatcga
    31501 actggtattg cgcaactaac agaacgtctt gcgttttgtt ggcgaagccg ctggtgtttg
    31561 taaatttatt agtgatcggc gtagcgttac gggtttcacc gtagttcgct gccaggtaga
    31621 tgttgttcgc gtcgtacttc agaccagtag cccactgttc agctttttta ccgttgccaa
    31681 gaggttgagc ttcttgcagg ttggtacggt cagctgcacc ataagcacca acgataccaa
    31741 agccttcgta ttcgtagctg atagaaccgc caacaccgtc gccgttagaa cggcgtgcag
    31801 tgtcacgctc gtttttaccc aggtactgaa cagcgaagtt caggccatca accagaccaa
    31861 agaagttgga gttacgatag gtagcaacgc cgccaacacg accaacgaag aagtcatcgc
    31921 tgtatgcagt atcaccacca aattctggca gcatatcggt gtaacccagt gcatcataaa
    31981 ccacaccgta gttacggccg taatcgaaag aaccaacgtc agcgtattta agacccgcga
    32041 atgccagacg cgttttgtta ccagtttgag cgtcagcgcc ttcagagttg ttaccctgga
    32101 agttatattc ccactgacca taaccggtca gatcggaatt gatttgagtt tcccctttaa
    32161 aaccaagacg ggcataggtc atgtcgccat tgccaccgta actgttttca ccgttaccct
    32221 tggaaaaata atgcagacca acagctttac cgtacagatc tactttgttg ccatctttgt
    32281 tatagatttc tgcagcgttt gcagtacctg ctactaacag agcagggacg atcactgcca
    32341 gaatattgcg cttcatcatt atttattacc ctcatggttt tttttatgac acctgccact
    32401 gccttcaata agttctgtca ataaaaattt acggaactat tgatgagagt ttggtgtctt
    32461 tatgtgtctg caggcatctt tccattcaaa ctaacgtttc gctaccgtga aagtgctaca
    32521 aagataaaga tttagtttca aaaagaaaaa atatgtaa
//
LOCUS       DAPGUL010000047        32314 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.047, whole genome shotgun sequence.
ACCESSION   DAPGUL010000047 DAPGUL010000000
VERSION     DAPGUL010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 32314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32314
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.047"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(90..1136)
                     /gene="aroH"
                     /locus_tag="RHX21_002326"
     CDS             complement(90..1136)
                     /gene="aroH"
                     /locus_tag="RHX21_002326"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroH"
                     /protein_id="HDV1987497.1"
                     /translation="MNRTDELRTARIESLVTPAELALRYPVTPGVAAHVTDSRRRIEK
                     ILNGEDKRLLVIIGPCSIHDLTAAMEYATRLQSLRNQYQSRLEIVMRTYFEKPRTVVG
                     WKGLISDPDLNGSYRVNHGLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGA
                     IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMT
                     IYQTSGNPYGHIIMRGGKKPNYHADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRR
                     QLEVCEDICQQIRNGSTAIAGIMAESFLREGTQKIVGSQPLTYGQSITDPCLGWEDTE
                     RLVEKLASAVDTRF"
     gene            complement(1293..2126)
                     /gene="ppsR"
                     /locus_tag="RHX21_002327"
     CDS             complement(1293..2126)
                     /gene="ppsR"
                     /locus_tag="RHX21_002327"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="posphoenolpyruvate synthetase regulatory
                     kinase/phosphorylase PpsR"
                     /protein_id="HDV1987498.1"
                     /translation="MDNAVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVE
                     NESRARAVKDQIDAIYHQTGVRPLVFYSIVLPEIRAIILQSEGFCQDIVQALVAPLQQ
                     EMKLDPTPIAHRTHGLNPNNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSR
                     CGKTPTSLYLAMQFGIRAANYPFIADDMDNLVLPASLKPLQHKLFGLTIDPERLAAIR
                     EERRENSRYASLRQCRMEVAEVEALYRKNQIPWINSTNYSVEEIATKILDIMGLSRRM
                     Y"
     gene            2459..4837
                     /gene="ppsA"
                     /locus_tag="RHX21_002328"
     CDS             2459..4837
                     /gene="ppsA"
                     /locus_tag="RHX21_002328"
                     /EC_number="2.7.9.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate synthase"
                     /protein_id="HDV1987499.1"
                     /translation="MSNNGSSPLVLWYNQLGMNDVDRVGGKNASLGEMITNLSGMGVS
                     VPNGFATTADAFNQFLDQSGVNQRIYELLDKTDIDDVTQLAKAGAQIRQWIIDTPFQP
                     ELENAIREAYAQLSADDENASFAVRSSATAEDMPDASFAGQQETFLNVQGFDAVLVAV
                     KHVFASLFNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASSGVMFSIDTESGFDQV
                     VFITSAWGLGEMVVQGAVNPDEFYVHKPTLAANRPAIVRRTMGSKKIRMVYAPTQEHG
                     KQVKIEDVPQEQRDIFSLTNEEVQELAKQAVQIEKHYGRPMDIEWAKDGHTGKLFIVQ
                     ARPETVRSRGQVMERYTLHSQGKIIAEGRAIGHRIGAGPVKVIHDISEMNRIEPGDVL
                     VTDMTDPDWEPIMKKASAIVTNRGGRTCHAAIIARELGIPAVVGCGDATERMKDGENV
                     TVSCAEGDTGYVYAELLEFSVKSSSVETMPDLPLKVMMNVGNPDRAFDFACLPNEGVG
                     LARLEFIINRMIGVHPRALLEFDDQEPQLQNEIREMMKGFDSPREFYVGRLTEGIATL
                     GAAFYPKRVIVRLSDFKSNEYANLVGGERYEPDEENPMLGFRGAGRYVSDSFRDCFAL
                     ECEAVKRVRNDMGLTNVEIMIPFVRTVDQAKAVVEELARQGLKRGENGLKIIMMCEIP
                     SNALLAEQFLEYFDGFSIGSNDMTQLALGLDRDSGVVSELFDERNDAVKALLSMAIRA
                     AKKQGKYVGICGQGPSDHEDFAAWLMEEGIDSLSLNPDTVVQTWLSLAELKK"
     gene            complement(4894..6540)
                     /gene="fadK"
                     /locus_tag="RHX21_002329"
     CDS             complement(4894..6540)
                     /gene="fadK"
                     /locus_tag="RHX21_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310435.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="medium-chain fatty-acid--CoA ligase"
                     /protein_id="HDV1987500.1"
                     /translation="MKVTLTFNEQRRAAYRQQGLWGDASLADYWQQTARAMPDKIAVV
                     DNHGASYTYSALDHAASCLANWMLAKGIESGDRIAFQLPGWCEFTVIYLACLKIGAVS
                     VPLLPSWREAELVWVLNKCQAKMFFAPTLFKQTRPVDLILPLQNQLPQLQQIVGVDKL
                     APATSSLSLSQIIADNTPLTTAITTHGDELAAVLFTSGTEGLPKGVMLTHNNILASER
                     AYCARLNLTWQDVFMMPAPLGHATGFLHGVTAPFLIGARSVLLDIFTPDACLALLEQQ
                     RCTCMLGATPFVYDLLNVLEKQPADLSALRFFLCGGTTIPKKVARECQQLGIKLLSVY
                     GSTESSPHAVVNLDDPLSRFMHTDGYAAAGVEIKVVDDARKTLPPGCEGEEASRGPNV
                     FMGYFDEPELTARALDEEGWYYSGDLCRMDEAGYIKITGRKKDIIVRGGENISSREVE
                     DILLQHPKIHDACVVAMPDERLGERSCAYVVLKAPHHSLSLEEVVAFFSRKRVAKYKY
                     PEHIVVIEKLPRTASGKIQKFLLRKDIMRRLTQDVCEEIE"
     gene            complement(6597..6890)
                     /locus_tag="RHX21_002330"
     CDS             complement(6597..6890)
                     /locus_tag="RHX21_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin family protein"
                     /protein_id="HDV1987501.1"
                     /translation="MSQNATVNVDIKLGVNKFHVDEGHPHIILAANPDINEFRKLMKA
                     CPAGLYKQDDAGNIHFDSAGCLECGTCRVLCGNTILEQWQYPAGTFGIDFRYG"
     gene            complement(6887..8176)
                     /locus_tag="RHX21_002331"
     CDS             complement(6887..8176)
                     /locus_tag="RHX21_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDV1987502.1"
                     /translation="MSEDKFDAIVVGAGVAGSVAALVMARAGLDVLVIERGDSAGCKN
                     MTGGRLYAHTLEAIIPGFAVSAPVERKVTREKISFLTEESAVTLDFHREQPDVPQHAS
                     YTVLRNRLDPWLMEQAEQAGAQFIPGVRVDALVREGNKVTGVQAGDDILEANVVILAD
                     GVNSMLGRSLGMVPASDPHHYAVGVKEVIGLTPEQINDRFNITGEEGAAWLFAGSPSD
                     GLMGGGFLYTNKDSISLGLVCGLGDIAHTQKSVPQMLEDFKQHPAIRPLISGGKLLEY
                     SAHMVPEGGLAMVPQMVNDGVMIVGDAAGFCLNLGFTVRGMDLAIASAQAAATTVIAA
                     KEREDFSASSLAQYKRELEQSCVMRDMQHFRKIPALMENPRLFSQYPRMVADIMNEMF
                     TIDGKPNQPVRKMIMGHAKKIGLINLLKDGIKGATAL"
     gene            complement(8232..9170)
                     /locus_tag="RHX21_002332"
     CDS             complement(8232..9170)
                     /locus_tag="RHX21_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit alpha"
                     /protein_id="HDV1987503.1"
                     /translation="MSQLNSVWVFSDNPERYAELFGGAQQWGQQVYAIVQNTDQAQAV
                     MPYGPKCIYVLEQNDALQRTENYAESIAALLKDKHPAMLLLAATKRGKALAARLSVQL
                     NAALVNDATAVDIIDGHICAEHRMYGGLAFAQEKINSPLAIITLAPGVQEPCTSDTSH
                     QCPTETVPYVAPRHEILCRERRAKAASSVDLSKAKRVVGVGRGLAAQDDLKMVHELAA
                     VLNAEVGCSRPIAEGENWMERERYIGVSGVLLKSDLYLTLGISGQIQHMVGGNGAKVI
                     VAINKDKNAPIFNYADYGLVGDIYKVVPALISQLSR"
     gene            complement(9190..9954)
                     /locus_tag="RHX21_002333"
     CDS             complement(9190..9954)
                     /locus_tag="RHX21_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein"
                     /protein_id="HDV1987504.1"
                     /translation="MKIITCFKLVPEEQDIVVTPEYTLNFDNADAKISQFDLNAIEAA
                     SQLATDDDEIAALTVGGSLLQNSKVRKDVLSRGPHSLYLVQDAQLEHALPLDTAKALA
                     AAVEKIGFDLLIFGEGSGDLYAQQAGLLVGEILQLPVINAVSAIQRQGNTLVIERTLE
                     DDVEVIELSVPAVLCVTSDINVPRIPSMKAILGAGKKPVNQWQASDIDWSQSAPLAEL
                     VGIRVPPQTERKHIIIDNDSPEAIAELAEHLKKALN"
     gene            10270..11181
                     /locus_tag="RHX21_002334"
     CDS             10270..11181
                     /locus_tag="RHX21_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDV1987505.1"
                     /translation="MYQRCFDNASETLFVAGKTPRLSRFAISDDPKWESGHHVHDNET
                     ELIYVKKGVARFTIDSSLYVAHADDIVVIERGRLHAVASDVNDPATTCTCALYGFQFQ
                     GAEENQLLQPHSCPVIAAGQGKEVIKTLFNELSVILPQSKNSQTSSLWDAFAYTLAIL
                     YYENFKNAYRSEQGYIKKDVLIKDILFYLNNNYREKITLEQLSKKFRASVSYICHEFT
                     KEYRISPINYVIQRRMTEAKWSLTNTELSQAEISWRVGYENVDHFAKLFLRHVGCSPS
                     DYRRQFKNCFAEQEILSEFPQPVSLVG"
     gene            complement(11224..12375)
                     /locus_tag="RHX21_002335"
     CDS             complement(11224..12375)
                     /locus_tag="RHX21_002335"
                     /EC_number="1.3.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310429.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HDV1987506.1"
                     /translation="MDFSLTEEQELLLASIRELITTNFPEEYFRTCDQNGTYPREFMR
                     ALADNGISMLGVPEEFGGIPADYVTQMLALMEVSKCGAPAFLITNGQCIHSMRRFGSA
                     EQLRKTAESTLETGDPAYALALTEPGAGSDNNSATTTYTRKNGKVYINGQKTFITGAK
                     EYPYMLVLARDPQPKDPKKAFTLWWVDSSKPGIKINPLHKIGWHMLSTCEVYLDNVEV
                     EESDMVGEEGMGFLNVMYNFEMERLINAARSTGFAECAFEDAARYANQRIAFGKPIGH
                     NQMIQEKLALMAIKIDNMRNMVLKVAWQADQHQSLRTSAALAKLYCARTAMEVIDDAI
                     QIMGGLGYTDEARVSRFWRDVRCERIGGGTDEIMIYVAGRQILKDYQNK"
     gene            complement(12389..13984)
                     /locus_tag="RHX21_002336"
     CDS             complement(12389..13984)
                     /locus_tag="RHX21_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl CoA:acetate/3-ketoacid CoA transferase"
                     /protein_id="HDV1987507.1"
                     /translation="MKPVKPPRINGRVPVLSAQEAVNYIPDEATLCVLGAGGGILEAT
                     TLITALADKYKQTQTPRNLSIISPTGLGDRADRGISPLAQEGLVKWALCGHWGQSPRI
                     SELAEQNKIIAYNYPQGVLTQTLRAAAAHQPGIISDIGIGTFVDPRQQGGKLNEVTKE
                     DLIKLVEFDNKEYLYYKAIAPDIAFIRATTCDSEGYATFEDEVMYLDALVIAQAVHNN
                     GGIVMMQVQKMVKKATLHPKSVRIPGYLVDIVVVDPDQSQLYGGAPVNRFISGDFTLD
                     DSTKLSLPLNQRKLVARRALFEMRKGAVGNVGVGIADGIGLVAREEGCADDFILTVET
                     GPIGGITSQGIAFGANVNTRAILDMTSQFDFYHGGGLDVCYLSFAEVDQHGNVGVHKF
                     NGKIMGTGGFIDISATSKKIIFCGTLTAGSLKTEIADGKLHIVQEGRVNKFIRELPEI
                     TFSGKIALERGLDVRYITERAVFTLKEDGLHLIEIAPGVDLQKDILDKMDFTPVISPE
                     LKLMDERLFIDAAMGFVLPEAAH"
     gene            complement(14128..14886)
                     /gene="aroD"
                     /locus_tag="RHX21_002337"
     CDS             complement(14128..14886)
                     /gene="aroD"
                     /locus_tag="RHX21_002337"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDV1987508.1"
                     /translation="MKTVTVKDLVIGTGAPKIIVSLMAKDIARVKSEALAYREADFDI
                     LEWRVDHFADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNR
                     AAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRK
                     MQSFDADIPKIALMPQSTSDVLTLLTATLEMQEQYADRPIITMSMAKTGVISRLAGEV
                     FGSAATFGAVKKASAPGQISVNDLRTVLTILHQA"
     gene            complement(14917..15783)
                     /gene="ydiB"
                     /locus_tag="RHX21_002338"
     CDS             complement(14917..15783)
                     /gene="ydiB"
                     /locus_tag="RHX21_002338"
                     /EC_number="1.1.1.282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinate/shikimate dehydrogenase"
                     /protein_id="HDV1987509.1"
                     /translation="MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKAGLPFTYMAFEV
                     DNDSFPGAIEGLKALKMRGTGISMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLR
                     GYNTDGTGHIRAIKESGFDIKGKTMVLLGAGGASTAIGAQGAIEGLKEIKLFNRRDEF
                     FDKALAFAQRVNENTDCVVTVTDLADQQAFAEALASADILTNGTKVGMKPLENESLVN
                     DISLLHPGLLVTECVYNPHMTKLLQQAQQAGCKTIDGYGMLLWQGAEQFTLWTGKDFP
                     LEYVKQVMGFGA"
     gene            complement(15795..17060)
                     /locus_tag="RHX21_002339"
     CDS             complement(15795..17060)
                     /locus_tag="RHX21_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310425.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1987510.1"
                     /translation="MSQNKAFSTPFILAVLCIYFSYFLHGISVITLAQNMSSLAEKFS
                     TDNAGIAYLISGIGLGRLISILFFGVISDKFGRRAVILMAVIMYLLFFFGIPACPNLT
                     LAYGLAVCVGIANSALDTGGYPALMECFPKASGSAVILVKAMVSFGQMFYPMLVSYML
                     LNNIWYGYGLIIPGILFVLITLMLLKSKFPSQLVDASVANELPQMNSKPLVWLEGVSS
                     VLFGVAAFSTFYVIVVWMPKYAMAFAGMSEAEALKTISYYSMGSLVCVFIFAALLKKM
                     VRPIWANVFNSTLATITAAIIYLYPSPLVCNAGAFVIGFSAAGGILQLGVSVMSEFFP
                     KSKAKVTSIYMMMGGLANFVIPLITGYLSNIGLQYIIVLDFTFALLALITAIIVFIRY
                     YRVFIIPENDVRFGERKFSTRLNTIKHRG"
     gene            complement(17287..18501)
                     /locus_tag="RHX21_002340"
     CDS             complement(17287..18501)
                     /locus_tag="RHX21_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1987511.1"
                     /translation="MKNPYYPTALGLYFNYLVHGMGVILMSLNMASLETLWQTNAAGV
                     SIVISSLGIGRLSVLLFAGLLSDRFGRRPFIMLGMCCYMAFFFGILHTNNIIIAYVFG
                     FLAGMANSFLDAGTYPSLMEAFPRSPGTANILIKAFVSSGQFLLPLIISLLVWAELWF
                     GWSFMIAAGIMFINALFLYRCTFPPHPGHRLPVIKKTTSSTEHRCSIIDLASYTLYGY
                     ISMATFYLVSQWLAQYGQFVAGMSYTMSIKLLSIYTVGSLLCVFITAPLIRNTVRPTT
                     LLMLYTFISFIALFTVCLHPTFYVVIIFAFVIGFTSAGGVVQIGLTLMAERFPYAKGK
                     ATGIYYSAGSIATFTIPLITAHLSQRSIADIMWFDTTIAAIGFLLALFIGLRSRKKTR
                     HQSLKENVAPGG"
     gene            complement(18601..18957)
                     /locus_tag="RHX21_002341"
     CDS             complement(18601..18957)
                     /locus_tag="RHX21_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707588.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiL family protein"
                     /protein_id="HDV1987512.1"
                     /translation="MNAYELQALRHIFAMTIDECATWIAQTGDSESWRQWENGKCAIP
                     DRVVEQLLAMRQQRKKHLHAIIEKINNRIGNNTMRFFPDLTAFQQVYPDGNFIDWKIY
                     QSVAAELYAHDLERLC"
     gene            complement(19093..19200)
                     /gene="rprA"
                     /locus_tag="RHX21_002342"
     ncRNA           complement(19093..19200)
                     /ncRNA_class="antisense_RNA"
                     /gene="rprA"
                     /locus_tag="RHX21_002342"
                     /product="antisense sRNA RprA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00034"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00034"
     gene            complement(19386..20498)
                     /gene="ydiK"
                     /locus_tag="RHX21_002343"
     CDS             complement(19386..20498)
                     /gene="ydiK"
                     /locus_tag="RHX21_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter YdiK"
                     /protein_id="HDV1987513.1"
                     /translation="MVNVRQPRDVAQILLSVLFLAIMIVACLWIVQPFILGFAWAGTV
                     VIATWPVLLRLQKIMFGRRSLAVLVMTLLLVMVFIIPIALLVNSIVDGSGPLIKAISS
                     GDMTLPDLAWLNTIPVIGAKLYAGWHNLLDMGGTAIMAKVRPYIGTTTTWFVGQAAHI
                     GRFMVHCALMLLFSALLYWRGEQVAQGIRHFATRLAGVRGDAAVLLAAQAIRAVALGV
                     VVTALVQAVLGGIGLAVSGVPYATLLTVLMILSCLVQLGPLPVLIPAIIWLYWTGDTT
                     WGTVLLVWSGVVGTLDNVIRPMLIRMGADLPLILILSGVIGGLIAFGMIGLFIGPVLL
                     AVSWRLFAAWVEEVPPPTDQPEEILEELGEIEKPNK"
     gene            20887..23943
                     /locus_tag="RHX21_002344"
     CDS             20887..23943
                     /locus_tag="RHX21_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDV1987514.1"
                     /translation="MIPQISQAPGVVQLVLNFLQELEQQGFTGDTATSYADRLTMSTD
                     NSIYQLLPDAVVFPRSTADVALIARLAAQERYSSLIFTPRGGGTGTNGQALNQGIIVD
                     MSRHMNRIIEINPEEGWVRVEAGVIKDQLNQYLKPFGYFFAPELSTSNRATLGGMINT
                     DASGQGSLVYGKTSDHVLGVRAVLLGGDILDTQPLPVELAETLGKSNTTIGRIYNTVY
                     QRCRQQRQLIIDNFPKLNRFLTGYDLRHVFNDEMTEFDLTRILTGSEGTLAFITEARL
                     DITPLPKVRRLVNVKYDSFDSALRNAPFMVEARALSVETVDSKVLNLAREDIVWHSVS
                     ELITDVPDKEMLGLNIVEFAGDDEALIDERVNALCARLDELIASHQAGVIGWQVCREL
                     AGVERIYAMRKKAVGLLGNAKGAAKPIPFAEDTCVPPEHLADYIAEFRALLDSHGLSY
                     GMFGHVDAGVLHVRPALDMCDPQQEILMKQISDDVVALTAKYGGLLWGEHGKGFRAEY
                     SPAFFGEELYAELRKVKAAFDPHNRLNPGKICPPEGLDAPMMKVDAVKRGTFDRQIPI
                     AVRQQWRGAMECNGNGLCFNFDARSPMCPSMKITQNRIHSPKGRATLVREWLRLLADR
                     GVDPLKLEQELPESGVSLRTLIARTRNSWHANKGEYDFSHEVKEAMSGCLACKACSTQ
                     CPIKIDVPEFRSRFLQLYHTRYLRPLRDHLVATVESYAPLMARAPKTFNFFINQPLVR
                     KLSEKHIGMVDLPLLSVPSLQQQMVGHRSANMTLEQLEALNAEQKARTVLVVQDPFTS
                     YYDAQVVADFVRLVEKLGFQPVLLPFSPNGKAQHIKGFLNRFAKTAKKTADFLNRMAK
                     LGMPMVGVDPALVLCYRDEYKLALGEERGEFNVLLANEWLASALESQPVATVSGESWY
                     FFGHCTEVTALPGAPAQWAAIFARFGAKLENVSVGCCGMAGTYGHEEKNHKNSLGIYE
                     LSWHQAMQRLPRNRCLATGYSCRSQVKRVEGTGVRHPVQALLEIIK"
     gene            23940..24350
                     /gene="menI"
                     /locus_tag="RHX21_002345"
     CDS             23940..24350
                     /gene="menI"
                     /locus_tag="RHX21_002345"
                     /EC_number="3.1.2.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA hydrolase"
                     /protein_id="HDV1987515.1"
                     /translation="MIWKRKITLEALNAMGEGNMVGLLDIRFEHIGDDTLEATMPVDS
                     RTKQPFGLLHGGASVVLAESIGSVAGYLCTEGEQKVVGLEINANHVRSAREGRVRGVC
                     KPLHLGSRHQVWQIEIFDEKGRLCCSSRLTTAIL"
     gene            24450..24638
                     /locus_tag="RHX21_002346"
     CDS             24450..24638
                     /locus_tag="RHX21_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416200.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiH family protein"
                     /protein_id="HDV1987516.1"
                     /translation="MSTQLDPTQLAIEFLRRDQSNLSPAQYLKRLKQLELEFADLLTL
                     SSAELKEEIYFAWRLGVH"
     gene            25187..25555
                     /gene="sufA"
                     /locus_tag="RHX21_002347"
     CDS             25187..25555
                     /gene="sufA"
                     /locus_tag="RHX21_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold SufA"
                     /protein_id="HDV1987517.1"
                     /translation="MDMHSGTFNPQDFAWQGLTLTPAAAIHIRELVAKQPGMVGVRLG
                     VKQTGCAGFGYVLDSVSEPDKDDLLFEHDGAKLFVPLQAMPFIDGTEVDFVREGLNQI
                     FKFHNPKAQNECGCGESFGV"
     gene            25564..27051
                     /gene="sufB"
                     /locus_tag="RHX21_002348"
     CDS             25564..27051
                     /gene="sufB"
                     /locus_tag="RHX21_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416198.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HDV1987518.1"
                     /translation="MSRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVR
                     AISAKRNEPEWMLEFRLNAYRAWLEMEEPHWLKAHYDKLNYQDYSYYSAPSCGNCDDT
                     CASEPGAVQQTGANAFLSKEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYREKLA
                     EQGIIFCSFGEAIHDHPELVRKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCP
                     MELSTYFRINAEKTGQFERTILVADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKN
                     AEVKYSTVQNWFPGDNNTGGILNFVTKRALCEGENSKMSWTQSETGSAITWKYPSCIL
                     RGDNSIGEFYSVALTSGHQQADTGTKMIHIGKNTKSTIISKGISAGHSQNSYRGLVKI
                     MPTATNARNFTQCDSMLIGANCGAHTFPYVECRNNSAQLEHEATTSRIGEDQLFYCLQ
                     RGISEEDAISMIVNGFCKDVFSELPLEFAVEAQKLLAISLEHSVG"
     gene            27061..27807
                     /gene="sufC"
                     /locus_tag="RHX21_002349"
     CDS             27061..27807
                     /gene="sufC"
                     /locus_tag="RHX21_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008500629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HDV1987519.1"
                     /translation="MLSIKDLHVSVEDKAILRGLSLDVRPGEVHAIMGPNGSGKSTLS
                     ATLAGREDYEVTGGTVEFKGKDLLALSPEDRAGEGIFMAFQYPVEIPGVSNQFFLQTA
                     LNAVRSYRGQETLDRFDFQDLMEEKIALLKMPEDLLTRSVNVGFSGGEKKRNDILQMA
                     VLEPELCILDESDSGLDIDALKVVADGVNSLRDGKRSFIIVTHYQRILDYIKPDYVHV
                     LYQGRIVKSGDFTLVKQLEEQGYGWLTEQQ"
     gene            27782..29053
                     /gene="sufD"
                     /locus_tag="RHX21_002350"
     CDS             27782..29053
                     /gene="sufD"
                     /locus_tag="RHX21_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HDV1987520.1"
                     /translation="MAGLPNSSNALQQWHHLFEAEGTKRSPQAQQHLQQLLRTGLPTR
                     KHENWKYTPLEGLTNSQFVSIAGEISPQQRDALALTLDAVRLVFVDGRYVSALSDATE
                     GSGYEVSINDDRQGVPDAIQAEVFLHLTESLAQSVTHIAVKRGQRPAKPLLLMHITQG
                     VAGEEVNTAHYRHHLDLAEGAEATVIEHFVSLNDARHFTGARFTINVAANAHLQHIKL
                     AFENPVSHHFAHNDLLLADDATAFSHSFLLGGAVLRHNTSTQLNGENSTLRINSLAMP
                     VKNEVCDTRTWLEHNKGFCNSRQLHKTIVSDKGRAVFNGLINVAQHAIKTDGQMTNNN
                     LLMGKLAEVDTKPQLEIYADDVKCSHGATVGRIDDEQMFYLRSRGINQQDAQQMIIYA
                     FAAELTEALRDEGLKQQVLARIGQRLPGGAR"
     gene            29050..30270
                     /gene="sufS"
                     /locus_tag="RHX21_002351"
     CDS             29050..30270
                     /gene="sufS"
                     /locus_tag="RHX21_002351"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase SufS"
                     /protein_id="HDV1987521.1"
                     /translation="MTFSVDKVRADFPVLSREVNGLPLAYLDSAASAQKPSQVIDAEA
                     EFYRHGYAAVHRGIHTLSAQATEKMENVRKRASLFINARSAEELVFVRGTTEGINLVA
                     NSWGNSNVRAGDNIIISQMEHHANIVPWQMLCARVGAELRVIPLNPDGTLQLETLPTL
                     FDEKTRLLAITHVSNVLGTENPLAEIITLAHQHGAKVLVDGAQAVMHHPVDVQALDCD
                     FYVFSGHKLYGPTGIGILYVKEALLQEMPPWEGGGSMIATVSLSEGTTWTKAPWRFEA
                     GTPNTGGIIGLGAALEYVSALGLNSIAEYEQNLMHYALSQLESVPDLTLYGPQNRLGV
                     IAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAYYNVPAMCRASLAMYNTHEEVD
                     RLVTGLQRIHRLLG"
     gene            30283..30699
                     /gene="sufE"
                     /locus_tag="RHX21_002352"
     CDS             30283..30699
                     /gene="sufE"
                     /locus_tag="RHX21_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfuration protein SufE"
                     /protein_id="HDV1987522.1"
                     /translation="MALLPDKEKLLRNFLRCANWEEKYLYIIELGQRLPELRDEDRSP
                     QNSIQGCQSQVWIVMRQNAQGIIELQGDSDAAIVKGLIAVVFILYDQMTPQDIVNFDV
                     RPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAAALS"
     gene            30848..31852
                     /gene="ldtE"
                     /locus_tag="RHX21_002353"
     CDS             30848..31852
                     /gene="ldtE"
                     /locus_tag="RHX21_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase LdtE"
                     /protein_id="HDV1987523.1"
                     /translation="MKRASLLTLTLIGAFSAIQAAWAVDYPLPPTGSRLVGQNQTYTV
                     QEGDKNLQAIARRFDTAAMLILEANNTIAPVPKPGTTITIPSQLLLPDAPRQGIIVNL
                     AELRLYYYPPGENIVQVYPIGIGLQGLETPVMETRVGQKIPNPTWTPTAGIRQRSLER
                     GIKLPPVVPAGPNNPLGRYALRLAHGNGEYLIHGTSAPDSVGLRVSSGCIRMNAPDIK
                     ALFSSVRTGTPVKVINEPVKYSVEPNGMRYVEVHRPLSAEEQQNVQTMPYTLPAGFTQ
                     FKDNKAVDQKLVDKALYRRAGYPVSVSSGATPAASNAPSVESAQNGEPEQGNMLRATQ
                     "
     gene            complement(31916..32152)
                     /gene="lpp"
                     /locus_tag="RHX21_002354"
     CDS             complement(31916..32152)
                     /gene="lpp"
                     /locus_tag="RHX21_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein lipoprotein Lpp"
                     /protein_id="HDV1987524.1"
                     /translation="MKATKLVLGAVILGSTLLAGCSSNAKIDQLSSDVQTLNAKVDQL
                     SNDVNAMRSDVQAAKDDAARANQRLDNMATKYRK"
BASE COUNT         8218 a         7971 c         8229 g         7896 t
ORIGIN      
        1 atattatggc taaccagagc aagcagtaat gtgctgagaa gacaacaagt tgcgcagaaa
       61 tgcccatccc atcaggaatg ggcacgcatt cagaagcggg tatctaccgc agaggcgagt
      121 ttttcgacca ggcgttcggt atcttcccag cccagacacg ggtcggtaat ggattgaccg
      181 taagtgagcg gctgactgcc gacgattttt tgcgttcctt cgcgcaggaa actttccgcc
      241 ataattccag caatcgccgt agagccattg cggatttgct gacaaatatc ctcacaaact
      301 tctaactggc gacggtgctg cttctggcag ttaccgtggc tgaaatccac caccagatgt
      361 tcaggtaaat caaactcgtg cagcgtatcg caggctgcgg cgatatcatc ggcatgataa
      421 ttcggttttt tgccgccacg cataataatg tggccatacg ggttgccgct ggtctgatag
      481 atggtcatct gaccattttt gtctggcgag aggaacatat ggctggcgcg ggctgcgcgg
      541 atagcatcca cggcaatccg cgtgttgcca tcggtaccat ttttaaaacc taccggacag
      601 gagagtgccg aagccatttc acggtggatc tgactttcgg tagtacgtgc gccaatcgcg
      661 ccccaactga ttaaatcagc aataaactga ccggtcacca tatcgaggaa ctcagtcgcg
      721 gtagggacac ccagctcatt tacctgtaaa agtaatttgc gcgccagctc cagaccgtga
      781 tttacccgat agctgccgtt taaatccgga tcggagatta gccctttcca gccgacaaca
      841 gttcgtggtt tttcaaaata ggtgcgcatt acgatttcca gccgtgactg gtactggttg
      901 cgcagcgact gcagacgggt ggcgtactcc attgcagcgg tgagatcgtg gatcgagcag
      961 gggccaataa taaccaacag tcgcttatct tcaccattca gtattttttc aattctgcgg
     1021 cgggagtcgg tgacatgggc ggcgacgcca ggcgttacgg gataccgtag cgcgagttcg
     1081 gcgggcgtta ccaggctctc aatacgcgca gtacggagtt cgtcagttct gttcattaca
     1141 agtctcagaa atttgttgct tctacggcag gactgccggg aagtgatgcg catcacgata
     1201 aaccaatcgc tgctgatttc aagtgcgagg tgtgtcacac ctcgccgggt ggttagcatg
     1261 ataacaaaaa aataagctaa tgcactagtt ctctagtaca ttcggcgact aaggcccatg
     1321 atatcgagga tcttggtggc aatctcttct accgaataat tggtactgtt aatccacggg
     1381 atctgatttt tacggtacaa cgcttccact tccgcgactt ccatcctgca ctgacgaagc
     1441 gaggcatagc gactgttctc ccgacgttcc tcgcgaatcg ccgccagacg ttccgggtcg
     1501 atagtcaggc cgaacaattt gtgctgaagc ggtttgagcg acgcgggtag caccagatta
     1561 tccatatcgt cggcaataaa ggggtagttt gccgcgcgga taccaaattg cattgccaga
     1621 tacagactgg tgggggtttt accacagcga gaaacgccga gcaggatcac ctgagcctgg
     1681 tccagattgc gcaacgaaat accgtcatcg tgggcaaggg tgtaatcaat cgccgcaatg
     1741 cgcgcatcat atttattgag attattaggg ttaaggccat gggtacgatg agcaatcggc
     1801 gttggatcca gtttcatctc ttgttgtagc ggggcaacca gcgcctgaac gatatcctgg
     1861 caaaagcctt cactttgcaa gatgatggcg cgaatctccg gcaacacgat ggagtagaag
     1921 accagcgggc gcacacctgt ctggtgataa attgcgtcaa tctgatcctt cactgcccgt
     1981 gcacggctct cattttcgac aaacggcagc gtaatgctgc tgatagtgac gggaaattgt
     2041 gacattactg cgtgtcctaa tacctccgca gttattgccg taccatcaga aatataaaaa
     2101 acgtggcgat caacagcatt atccattttg ttcttcccgt gatgcagaca taattctatg
     2161 aaagcataaa ttaaaaacgc acagaagcgt aggacgtaat gtctggttta taaaatgaac
     2221 cttcaatttt attttttatg aaaacagcat ttcattttta tggtttcgtt tataccgatg
     2281 gtttatgtgg aaattgtcga atagagcagg tttgcgcaac gctgggatca gtcttaaaaa
     2341 gtaaaaaaat atatttgctt gaacgattca ccgttttttt catccggtta aatatgcaaa
     2401 gataaatgcg cagaaatgtg tttctcaaac cgttcattta tcacaaaagg attgttcgat
     2461 gtccaacaat ggctcgtcac cgctggtgct ttggtataac caactcggca tgaatgatgt
     2521 agacagggtt gggggcaaaa atgcctccct gggtgaaatg attactaacc tttccggaat
     2581 gggtgtttcc gttccgaatg gtttcgccac aaccgccgac gcgtttaacc agtttctgga
     2641 ccaaagcggc gtaaaccagc gcatttatga actgctggat aaaacggata ttgacgatgt
     2701 tacccagctt gcgaaagcgg gcgcgcaaat ccgccagtgg attatcgaca ctcccttcca
     2761 gcctgagctg gaaaatgcca tccgcgaagc ttatgcacag ctttccgccg atgacgaaaa
     2821 cgcctctttt gcggtgcgct cctccgctac tgcagaagat atgccggacg cttcctttgc
     2881 cggtcagcag gaaaccttcc tcaacgttca gggttttgac gccgttctcg tggcagtgaa
     2941 acatgtattt gcttctctgt ttaacgatcg cgccatctct tatcgtgtgc accagggtta
     3001 cgatcaccgt ggcgtggcgc tctccgccgg tgttcaacgg atggtgcgct ctgacctcgc
     3061 atcttctggc gtgatgttct ccattgatac cgaatccggc tttgaccagg tggtgtttat
     3121 cacttccgca tggggccttg gtgaaatggt cgtgcagggc gcggttaacc cggatgagtt
     3181 ttacgtccat aaaccgacac ttgcagcgaa tcgcccggct atcgtgcgtc gcaccatggg
     3241 gtcgaaaaaa atccgcatgg tttacgcgcc gacccaggag cacggcaagc aggttaaaat
     3301 cgaagacgta ccgcaggaac agcgtgacat cttctcgctg accaacgaag aagtgcagga
     3361 actggcaaaa caggccgtac aaattgagaa acactacggt cgcccgatgg atattgagtg
     3421 ggcgaaagat ggccacaccg gcaaactgtt cattgtgcag gcgcgtccgg aaaccgtgcg
     3481 ctcacgcggt caggtcatgg agcgttatac gctgcattca cagggtaaga ttatcgccga
     3541 aggccgtgct atcggtcatc gcatcggcgc gggtccggtg aaagtcatcc atgacatcag
     3601 cgaaatgaac cgcatcgaac ctggcgacgt gctggtcact gacatgaccg acccggactg
     3661 ggaaccgatc atgaagaaag catctgccat cgtcaccaac cgtggcggtc gtacctgtca
     3721 cgcggcgatc atcgctcgtg aactgggcat tccggcggta gtgggctgtg gtgatgcaac
     3781 agaacggatg aaagacggtg agaacgtcac tgtttcttgt gccgaaggtg ataccggtta
     3841 cgtctatgcg gagttgctgg aatttagcgt gaaaagctcc agcgtagaaa cgatgccgga
     3901 tctgccgttg aaagtgatga tgaacgtcgg taacccggac cgtgctttcg acttcgcctg
     3961 cctgccgaac gaaggcgtgg gccttgcgcg tctggaattt atcatcaacc gtatgattgg
     4021 cgtccaccca cgcgcactgc ttgagtttga cgatcaggaa ccgcagttgc aaaacgaaat
     4081 ccgcgagatg atgaaaggtt ttgattctcc gcgtgaattt tacgttggtc gtctgactga
     4141 agggatcgcg acgctgggtg ccgcgtttta tccgaagcgc gtcattgtcc gtctctctga
     4201 ttttaaatcg aacgaatatg ccaacctggt cggtggtgag cgttacgagc cagatgaaga
     4261 gaacccgatg ctcggcttcc gtggcgcggg ccgctatgtt tccgacagct tccgcgactg
     4321 cttcgcgctg gagtgtgaag cagtgaaacg agtgcgcaac gacatggggc tgaccaacgt
     4381 tgagatcatg atcccgttcg tgcgtaccgt agatcaggcg aaagcggtgg ttgaagaact
     4441 ggcgcgtcag gggctgaaac gtggcgagaa cgggctgaaa atcatcatga tgtgtgaaat
     4501 tccgtccaac gccttgctgg cagagcagtt cctcgaatat ttcgacggct tctcaattgg
     4561 ctcaaacgat atgacacagc tggcgctcgg tctggatcgt gactccggcg tggtgtctga
     4621 attgttcgat gagcgcaacg atgcggtgaa agcattgctg tcgatggcta tccgtgccgc
     4681 gaagaaacag ggcaaatatg tcgggatttg cggtcagggt ccgtccgacc atgaagactt
     4741 tgccgcatgg ttgatggaag aggggatcga tagcctgtct ctgaacccgg acaccgtggt
     4801 gcaaacctgg ttaagcctgg ctgaactgaa gaaataaaat aaatccccgg cggcgttcag
     4861 tcgccgggtt tatgtgatcc ccgaagataa aacttattca atctcttcac agacatcctg
     4921 cgttaatcgc cgcataatat cttttcttaa caaaaacttt tgtattttac ctgaggcagt
     4981 gcgcggtagt ttttcgatta ccacgatatg ttcaggatat ttatattttg cgacccgttt
     5041 acggctaaaa aaagccacca cctcttccag cgataatgaa tgatgcggcg ctttcagcac
     5101 gacataagcg catgatcgtt cacctaaacg ttcatcgggc attgcaacca cacaggcatc
     5161 gtgaatttta ggatgctgca ataaaatatc ttccacttca cggctgctaa tattttcgcc
     5221 gccgcggaca ataatatctt ttttgcgtcc ggtaattttt atatagccag cctcatccat
     5281 acggcagaga tcgccgctgt aataccagcc ttcttcatcc agcgcacggg cggttaattc
     5341 aggttcatca aaatatccca taaacacatt ggggccacgc gaggcttctt caccttcgca
     5401 acctggcggt aaggtcttgc gtgcgtcatc gaccacttta atctctacac ctgcggcagc
     5461 gtaaccatcg gtgtgcataa agcgcgacaa aggatcatcg agattcacca ccgcatgcgg
     5521 cgaactttct gtggaaccat aaacacttaa taatttaatg ccgagctgct ggcattcacg
     5581 cgccactttt ttggggattg tggttccgcc gcaaagaaag aaacgcagcg ctgacaggtc
     5641 cgcgggttgt ttctctagta cattcaaaag atcatagaca aacggcgttg cgcctagcat
     5701 acaggtgcaa cgctgctgct caagcagcgc gagacacgca tcaggagtga aaatatctaa
     5761 caacacgctg cgagcgccaa ttaagaatgg tgccgttacg ccatgcagaa agcccgttgc
     5821 gtggccgagt ggcgcaggca tcataaagac atcctgccag gtcagattca gccgcgcgca
     5881 ataagcccgc tcactggcga gaatattgtt atgcgttagc atcacgccct ttggcagacc
     5941 ctcggttccg gaggtaaaca gcaccgcagc taattcatcg ccgtgggtcg ttatcgccgt
     6001 ggtcagtggg gtattgtcgg cgataatctg acttaatgag agggaagagg tggcgggagc
     6061 cagtttgtcc acgccgacaa tttgttgtag ttgtggaagc tgattttgca gcggcaggat
     6121 taaatctacc gggcgcgttt gtttaaacaa cgtcggtgca aagaacattt ttgcctgaca
     6181 cttattgagc acccacacca gttctgcttc ccgccaggaa ggcaacagcg gcacggaaac
     6241 cgcaccgatt ttcaggcagg caagatagat aacggtaaat tcacaccagc caggcagttg
     6301 aaatgcgatg cgatcgcctg attcaatacc cttcgctaac atccagtttg ccagacagct
     6361 cgcggcgtga tcgagcgcgc tataggtgta cgatgcacca tgattatcga ccacggcaat
     6421 tttgtctggc atcgcacgag cggtctgctg ccagtaatcg gccagcgaag catcgcccca
     6481 tagcccttgc tgacgatacg ccgcacgacg ttgttcgttg aacgttaatg tcactttcat
     6541 gttggactct cgaaacagaa catcaggccc gagatgcggg cctgtgggat gcatgattag
     6601 ccgtagcgaa aatcaatacc gaaggtgcct gcgggatatt gccactgttc gagaatagtg
     6661 ttaccgcaca gcacccgaca ggtgccgcac tccagacaac cggcagaatc aaaatgaatg
     6721 ttgccggcgt catcctgctt ataaagtccg gcagggcagg ctttcattaa tttacggaat
     6781 tcattgatat cgggatttgc cgccagaatg atatgcgggt ggccctcatc aacatggaat
     6841 ttattgacgc ctaatttgat gtcgacgtta accgtagcgt tctggctcat agcgcggttg
     6901 ctcccttaat gccatctttc agcaagttga tcagcccaat tttcttcgca tgtcccatga
     6961 tcattttgcg taccggctgg tttggtttgc cgtcaatggt gaacatctcg ttcatgatgt
     7021 cggcgaccat tcgtgggtat tggctaaaca ggcgcgggtt ttccatcagc gccgggatct
     7081 tgcggaaatg ctgcatatcg cgcatgacgc agctttgttc cagctcacgt ttgtattgcg
     7141 ccagactgct ggcggagaaa tcctcgcgtt ctttggcggc gatcaccgtt gtggcggcag
     7201 cctgagccga tgcaatggct aaatccatgc cacgaactgt aaaacccaaa ttcaggcaga
     7261 agcctgcggc gtcaccaacg atcatcacgc catcgttaac catctgcggc accattgcca
     7321 gaccgccttc tggcaccata tgcgcggaat attcaagcag tttgccgccg ctaattagtg
     7381 ggcgaatggc ggggtgttgt ttaaaatctt ccagcatttg cggcacgctt ttttgcgtat
     7441 gggcgatatc acccaatcca caaaccagcc ccaaggatat ggaatccttg ttggtataga
     7501 gaaatccccc gcccatcagg ccgtcagaag gggaaccggc aaacagccag gcggcacctt
     7561 cctcgcccgt aatattaaag cgatcgttga tctgttctgg tgtgaggcca ataacctctt
     7621 taacaccaac agcgtaatga tgcggatcgg aagcgggaac cattcccagc gagcggccaa
     7681 gcatcgagtt aacgccatca gccagaatca ccacattcgc ttcgagaata tcatccccag
     7741 cctgcacgcc agtgaccttg tttccttcac gaaccagcgc atcgacgcga acgcctggga
     7801 taaactgcgc gcccgcctgc tcggcttgtt ccatcaacca cgggtccaga cgattacgca
     7861 atacggtata agatgcgtgt tgcggaacat ctggttgctc gcggtgaaaa tcgagggtaa
     7921 cggcgctttc ttcggttaag aaggagattt tctcgcgtgt gaccttgcgt tctaccggcg
     7981 ctgatactgc aaagcctgga atgattgctt caagtgtgtg ggcataaaga cgcccgccgg
     8041 tcatgttttt acatccggca ctgtcgccgc gttctatcac caggacatcc agcccggctc
     8101 gcgccatgac cagtgcggca acgctaccag caacgcccgc accgaccaca atggcatcaa
     8161 atttgtcttc cgacatgcgt tatgctccct tcccgctgcg tttacagcgg gagatgtggt
     8221 tgaaagggga attagcggct caactggcta atcagggcag ggacgacttt gtagatatcg
     8281 cccaccagac cgtagtcggc ataattgaag attggcgcat ttttatcttt attgatggcg
     8341 acaatcactt ttgcgccgtt gccgccaacc atatgctgga tctgcccgga gatccccagc
     8401 gtcaggtaga gatcggattt cagcaacacg ccggagacac cgatataacg ttcacgctcc
     8461 atccagttct cgccttcggc aattggacgt gaacagccga cttcagcatt cagcaccgcc
     8521 gccagttcgt ggaccatttt caggtcatcc tgcgccgcca gaccacgacc gacgccaacc
     8581 acacgttttg ctttgctcag gtccacgctg cttgcggctt tcgcacggcg ttcgcgacag
     8641 agaatttcat gacgcggagc aacataaggt accgtttctg tcgggcactg atgagaggta
     8701 tcactggtgc acggttcctg aacaccgggt gcaagggtaa tgatcgccag cgggctgttg
     8761 atcttttcct gagcgaacgc taacccgcca tacatccggt gttcggcgca aatgtgacca
     8821 tcgataatat ccaccgccgt ggcatcgttc accagcgccg cattcagttg cacacttaac
     8881 cgtgctgcca gagctttacc acgtttcgtc gcggccaaca gcaacatagc ggggtgttta
     8941 tctttcagca gggcagcaat gctttcggcg taattttcag tgcgttgcag cgcgtcgttt
     9001 tgctcaagaa cataaataca ttttggacca taaggcataa ctgcctgcgc ctggtcggta
     9061 ttttgtacaa tggcatacac ctgttggccc cattgctgag cgccgccaaa cagttcagca
     9121 taacgttcag gattatcgct aaagacccag acgctgttta attgactcat cgtttcttct
     9181 ccgtaggctt cagttcaggg ctttcttcag atgttccgcc agctcggcaa tggcctccgg
     9241 cgaatcgtta tcgataatga tgtgcttacg ttctgtttgc ggcggtacgc gaatgccgac
     9301 cagttcagca agtggcgcgc tctggctcca gtcaatatca cttgcctgcc actgatttac
     9361 cggtttttta cccgcgccga gaatggcttt catcgaagga atgcgtggca cgttaatatc
     9421 ggaggtgacg cagagcacgg ctggaacaga gagttcaata acttcaacat catcttcaag
     9481 cgtgcgttca atcaccagtg tattgccctg acgctgaata gcactcactg cattaatcac
     9541 cggaagttgc agaatttctc cgaccagcaa gccagcctgc tgggcataaa ggtcgccgga
     9601 accttcacca aagatcagta aatcgaagcc gatcttttca actgctgccg ccagcgcttt
     9661 tgcggtatcg agaggcagtg catgttcaag ttgcgcatcc tgcaccaaat acaggctgtg
     9721 cggcccgcgg gatagcacgt ctttgcgcac tttcgagttc tgcaacaatg agccgccaac
     9781 ggtcagcgcg gctatctcat cgtcatctgt tgcgagctgg cttgcagctt caatggcatt
     9841 gagatcgaac tggctgattt tggcgtcggc attgtcgaaa ttcagggtgt attctggagt
     9901 gacaacaatg tcctgttctt caggcaccag cttaaagcag gttattattt tcatgatttc
     9961 tcctgtgagt cgcatacgga accatctccg atggaaggta aaaatggcct gaaaatagtg
    10021 tgcgatagcg gtgcggggtt ttcgacggag caagctgttt tccttgccaa caatcttgca
    10081 aaaaaaatgc gatcgctaaa acaaaagtgc aatttgcggc aatatagtta ttccatgacc
    10141 gtacaatctt gcattcagtg taaataatct tgtttagctc tcgctaaacg cggttgtata
    10201 accgcaatac acgccgtatt ttatccggca tatattgttt ttgcttgctc atggaatagg
    10261 gaggttgtca tgtatcaacg ctgttttgat aatgccagtg aaacgctgtt tgtcgccggt
    10321 aaaacgccac ggctttcacg ttttgcaatt agcgatgatc caaaatggga gtctggacat
    10381 cacgttcatg acaatgaaac cgagctgatt tacgtcaaga aaggggtagc aaggtttacc
    10441 atcgattcat cgttatatgt cgcacatgcc gatgatatag tggtgataga acgcggcagg
    10501 ctgcatgcgg tggcctctga cgttaacgat ccggcaacga cgtgtacctg tgcgctgtac
    10561 ggctttcagt ttcagggggc tgaggaaaat cagctactgc aaccgcattc ttgtccggta
    10621 attgccgcgg ggcagggaaa agaagtcata aaaaccttat ttaatgagct aagtgtgatt
    10681 ttgccgcaaa gtaaaaatag ccaaacatct tcgttatggg atgcatttgc ctatacgtta
    10741 gccattcttt actacgaaaa ttttaaaaat gcttatcgtt cggagcaggg gtatattaaa
    10801 aaagatgttc tgataaaaga tattcttttc tatctgaata ataattatcg cgaaaaaatc
    10861 actttagaac agttatcgaa aaaatttcgt gccagcgtca gttatatttg ccatgaattt
    10921 accaaagagt atcgtatttc ccctattaac tatgttattc aacggcgtat gacggaagca
    10981 aaatggtcac tcactaatac tgaattatca caggcagaga tctcctggcg tgtgggttat
    11041 gaaaatgtcg atcactttgc caaactgttt ttgcgccatg tcggttgttc gcccagcgat
    11101 taccgtagac aatttaaaaa ctgttttgcg gaacaagaaa tcctatctga atttcctcaa
    11161 ccggtaagtc ttgttggata aatctggcgg cgcagtttgt taagaagctg cgccgcctgc
    11221 agattatttg ttctgatagt ctttcaggat ctgccgacct gctacgtaaa tcataatttc
    11281 gtctgtaccg ccgccgatac gttcacaacg gacatcacgc cagaagcggg agacgcgcgc
    11341 ttcatcggta tagcccagac cgcccatgat ttgaatcgca tcatcaatga cttccattgc
    11401 ggtacgtgcg caatacagtt ttgccagcgc cgcgctggtg cgcagtgact gatgctgatc
    11461 ggcttgccat gccactttca gcaccatgtt gcgcatgttg tcgatcttaa tcgccatcag
    11521 cgccagtttt tcctggatca tctggttatg accaatgggc ttaccaaaag cgatacgttg
    11581 gttggcatag cgggcggcat cttcaaaggc gcattcggca aagccggtgc tgcgcgcggc
    11641 gttgatcagg cgctccatct caaagttgta catcacattg aggaaaccca ttccttcttc
    11701 gcccaccatg tcgctctctt caacctccac gttgtcgaga tagacttcgc aggtgctgag
    11761 catatgccag ccgattttat gcagcgggtt aatcttaatg ccgggcttac tggagtcgac
    11821 ccaccacagg gtgaaggctt ttttgggatc tttcggttgc ggatcgcgcg ccaacaccag
    11881 catatacggg tactctttcg caccggtaat aaaggttttt tgtccgttga tgtagacctt
    11941 gccgttttta cgcgtgtaag tggtagtggc actgttgtta tctgagccag cacctggttc
    12001 cgtcaacgcc agggcatagg cgggatcacc cgtttccagg gtgctttctg ccgttttacg
    12061 tagctgctct gcagaaccga aacggcgcat actgtgaata cattgaccgt tggtgatcaa
    12121 aaatgccgga gcaccgcatt ttgacacttc catcagcgcc agcatttggg tgacgtaatc
    12181 cgcagggata ccaccaaatt cttccggcac gccaagcatg gaaataccgt tatccgccag
    12241 cgcccgcata aactcacgcg gatatgtccc gttttgatcg caggtgcgga aatactcttc
    12301 cggaaagtta gtcgtaatca gttcgcgaat actggccagc agcagttctt gttcttcagt
    12361 taaagaaaaa tccatcatta tactcctgtt aatgagccgc ttcaggcagg acaaaaccca
    12421 tcgccgcatc gataaataat ctttcgtcca tcagtttgag ttctggcgaa atcactgggg
    12481 tgaagtccat tttgtcgaga atatcttttt gtaaatcgac gccaggggcg atttcgatta
    12541 aatgcaggcc gtcttctttc agcgtgaata cagcacgttc ggtgatgtaa cgaacatcca
    12601 gtccccgttc gagcgcgatt tttccgctaa aagtaatttc cggtagttcc cgaataaatt
    12661 tatttacccg tccttcctgg acgatatgca atttgccatc ggcaatttct gtttttaaac
    12721 tgcccgcagt taacgtgccg cagaaaataa ttttcttcga ggtggcactg atatcaataa
    12781 atccaccggt acccatgatt ttgccattga atttatgcac gccgacgtta ccgtgctggt
    12841 cgacttcagc aaaactcaaa taacaaacat ccagaccacc accgtgataa aaatcaaact
    12901 gggacgtcat atccagaatg gcgcgggtat tcacgttcgc gccaaaggcg ataccctgtg
    12961 aagtaattcc gccaatcgga cctgtttcta ccgtcagaat aaagtcatca gcacaacctt
    13021 cttcccgggc gaccaggcca ataccgtcag caataccgac gccgacattc cccaccgcgc
    13081 ctttacgcat ttcgaataat gcacgccgcg caactaattt acgttggttt aggggcaggc
    13141 taagtttggt gctgtcatca agggtgaagt caccagaaat aaaacggtta accggcgcac
    13201 cgccatacag ttggctttga tccggatcga ccaccacaat atccaccaga taacccggaa
    13261 tacggacaga tttaggatgc agcgtggctt tcttaaccat tttctgcacc tgcatcatca
    13321 caataccgcc gttattgtgc accgcctggg caataaccaa tgcgtcgaga tacatcacct
    13381 catcttcaaa agtggcgtag ccttcactgt cgcaggtggt agcgcgaatg aaggcgatat
    13441 ctggcgcaat cgctttgtaa tagagatatt ctttgttatc aaactcgacc agtttaatca
    13501 ggtcttcttt cgtgacttca ttcagtttgc cgccttgctg gcgtggatcg acaaatgtcc
    13561 cgatgccaat atcactaata ataccaggct ggtgggctgc ggcggcgcgt aaggtttgtg
    13621 taagtacacc ttgtggatag ttataagcaa taattttatt ttgttctgcg agttcagaaa
    13681 tacgcggcga ttgtccccag tgaccacata atgcccattt caccagacct tcttgcgcca
    13741 gaggactaat accgcggtcg gcgcgatcgc caagccctgt tggactaata atcgataaat
    13801 tacgtggcgt ttgagtctgt ttatatttat cagcaagagc agtaattaac gtggtggctt
    13861 ccagaatacc gccgccagcg cctaacacac aaagtgttgc ttcgtcggga atataattca
    13921 ccgcttcctg tgccgacagg accggcactc gtccattaat acgaggtggt tttacaggtt
    13981 tcattgttaa ttcctgattc agatgtgatt ttccctacgc cagatggaga attagcgcac
    14041 agagactcac gaaatatttt tattaaatac ggttaaatat attttttaag ttcggcgggg
    14101 agggtgttcc cgccgaaata ttattgctta tgcctggtgt aaaatagtta ataccgtgcg
    14161 taaatcattt accgagattt gccctggtgc agaggctttt tttaccgcac caaaagttgc
    14221 cgccgagcca aatacttcac cagccagacg agaaattacg ccagtttttg ccatcgacat
    14281 cgtgatgatt ggacgatcgg catactgctc ctgcatctcc agggtcgcgg taagcaacgt
    14341 cagcacatcg ctggtacttt gcggcatcag cgcaatctta ggaatatcgg cgtcgaagga
    14401 ctgcattttg cgcagacggg caatgatttc ttcggcttcc ggcgttttat ggaagtcatg
    14461 gttggacatg acaactttca catcatgcgc gtgggcgtag gcgacggttt ctttaacctg
    14521 atcatcgccg gtaaataact ccagatcgat catatcaacc aggccgctgt cgatggctgc
    14581 acgattgaga gcaatataag cctcggtgga aatcgcctgc tcgccgcctt ctttggcact
    14641 gcggaaggta aacagcagcg gtttttctgg catggtttca cggagaattt ttgccgccgc
    14701 catgacagac tccacattgg agaggtcggc aaagtggtcc acacgccatt ccagaatatc
    14761 aaagtccgct tcacgatagg cgagagcttc ggatttcacg cgggcgatat ctttcgccat
    14821 cagcgagacg atgattttag gtgcgcccgt accaatgacg agatctttta cagttacggt
    14881 tttcattttt taccctttct gcacgcggtc agcctgtcag gcaccgaacc ccatgacctg
    14941 tttaacatat tccagaggga aatctttgcc agtccataac gtgaactgtt cagccccttg
    15001 ccacaacaac atgccgtatc catcaatcgt tttgcaacca gcttgttgcg cctgctgcaa
    15061 taacttcgtc atatgcgggt tatacacgca ttcagtgacc agcagtcccg gatgtaacag
    15121 actgatatca ttaactaatg attcattctc aaggggtttc atacccactt ttgtgccatt
    15181 ggttaaaatg tcggcggaag ccagggcttc agcaaaggct tgctgatcgg cgagatcggt
    15241 aaccgtgacg acacaatcgg tgttttcgtt aacccgctgc gcgaaggcga gggctttatc
    15301 gaagaactca tcccgacggt taaagagttt aatttctttt aaaccttcaa ttgccccctg
    15361 cgcgccaatc gccgttgagg cacctccggc ccctaacagc accattgttt tgcctttgat
    15421 atcaaaaccg ctctctttaa tggctcgaat atggcccgtg ccgtcggtgt tatagccgcg
    15481 caggtaacca tcatcattaa cgatggtgtt gatggcaccc accagtttgg ctgctggcgt
    15541 taattcatca acatattcac acgccagttg tttgttcggc attgatatac cagttccgcg
    15601 cattttgagg gcttttaatc cttcaattgc tccgggaaaa ctatcgttat ccacttcaaa
    15661 ggccatatag gtaaatggca atcccgcttt ttctaaggct ttattctgca tttcaggcga
    15721 taaactgtgg cggataggat aggccatcag cccaatcaat tcgtattttg cggtaacatc
    15781 cataattaac tcctttaacc tctatgctta attgtgttta atcgggtgct aaatttgcgc
    15841 tcgccaaacc gcacatcatt ctcaggaata ataaaaacgc ggtaatagcg gataaaaaca
    15901 ataattgcgg taatcagggc cagcagcgcg aaagtaaaat cgagaacaat gatatattgc
    15961 aggccgatgt tcgacagata accggtaatc agcggaataa caaagttagc cagtccaccc
    16021 atcatcatat aaatactggt gactttggct ttgctttttg gaaaaaactc tgacatgacc
    16081 gaaacaccga gctgtaaaat gccgccagct gctgagaaac cgataacaaa ggcgccggca
    16141 ttacacacca gtggagaagg gtacaggtag ataatggctg ctgttattgt tgccagtgta
    16201 gagttaaata cattagccca gatgggccgg accatttttt tcagtagtgc ggcaaaaata
    16261 aagacacaga ccaacgagcc catactgtaa taagagatgg tttttaatgc ctcagcttct
    16321 gacataccag caaaagccat cgcatatttg ggcatccaca ccacaatcac ataaaaggtc
    16381 gagaatgcgg ctacaccgaa cagtaccgat gaaacacctt ccagccagac taacggtttg
    16441 ctgttcattt gcggtaattc attagctacg ctggcgtcca ccaactggct ggggaatttg
    16501 cttttcaaca gcatcagcgt gatcagtaca aataggatgc ctggaataat cagcccatag
    16561 ccgtaccaga tgttattgag caacatatag ctcaccagca ttgggtagaa catttgtccg
    16621 aatgacacca tcgctttaac cagtatgacc gccgaaccag aggctttcgg aaagcattcc
    16681 atgagcgcgg ggtagccacc cgtatccagc gctgagttag cgatacctac gcacactgcc
    16741 agaccgtagg cgagagttaa attcgggcaa gcgggaatac caaagaagaa tagcagatac
    16801 attattactg ccattaatat caccgcccga cgaccaaact tatcggagat cacaccgaag
    16861 aataaaatac tgatcaatcg ccccaaaccg ataccggaaa ttaaataggc aatgcccgcg
    16921 ttgtcagtgg aaaacttttc cgccagagat gacatgtttt gggcaagcgt aataacacta
    16981 atgccgtgca ggaagtagct gaagtaaata caaagaacag ccaggataaa tggcgtgctg
    17041 aaagccttat tttgagacat tttcacagct ccttgctgaa agataatttc gttaccgtac
    17101 gtattgttct ccgacggttt acataattac tatactgaag atgattttcc ctgggtacat
    17161 ggcataaagt ttatgtttcc aggaatattg catgtcatag tttgtttttg atcgcgattt
    17221 tccttagtta gcgcagaaag agttatttat ccgtaagatc ttgcatgacc tgaaaagaat
    17281 attgcattac ccacccggag cgacattttc ctttagcgac tgatgccgcg tttttttgcg
    17341 gctgcgtaag ccgataaaca gtgccagtaa aaaaccgatg gcagcgatgg tggtatcgaa
    17401 ccacataata tcggcaatac ttctttggga cagatgagcc gtaatcaacg gaatagtaaa
    17461 ggtcgcaata ctgcccgcac tgtaatagat ccctgtagct ttacctttag cgtaagggaa
    17521 acgttcagcc attaacgtca ggccaatttg cacaacacct ccagcagagg taaaaccaat
    17581 gacaaaagca aatattatca ccacataaaa tgtgggatgc aggcagacgg taaacagagc
    17641 aataaatgag ataaaggtgt acagcatcag taatgttgtt gggcgaacgg tattacgaat
    17701 gagtggagcg gtaataaata cacaaagcag cgaacccacg gtgtagatac tgagtagttt
    17761 aatcgacata gtgtatgaca tgcctgcaac aaattgtccg tactgtgcca gccactggct
    17821 aaccagataa aacgttgcca ttgagatata gccatataag gtataactgg ctaaatcgat
    17881 aattgaacag cgatgttccg tagagctggt ggttttcttt atgacaggta agcgatgacc
    17941 cggatggggt gggaacgtac aacggtataa aaacagagcg ttaataaaca taatgcctgc
    18001 agcaatcata aaggaccaac cgaaccacag ttcagcccac actaacaggc taatgattag
    18061 cggtaataaa aattgtccgc tggaaacaaa tgctttaatt aaaatattgg ctgtcccagg
    18121 tgagcgtgga aaagcttcca tcaaactggg ataagtgcct gcatcgagaa aactgtttgc
    18181 cattcctgcc agaaagccaa aaacataagc gataatgatg ttattggtgt gcaggatgcc
    18241 aaaaaagaag gccatatagc agcacatccc gagcatgata aaagggcggc gaccaaagcg
    18301 atcggataat aatcctgcaa aaagcaagac acttaatcga ccaatgccca gcgatgagat
    18361 aactatcgag acacccgcgg cattagtctg ccaaagtgtc tccagcgagg ccatattcag
    18421 gctcatcaaa atgacgccca taccatgcac caggtaatta aaatacaacc caagtgcggt
    18481 agggtaatag ggatttttca taggttctac ttagcaaagg tgctttaaaa agtgtagcga
    18541 tgttgtgtca gtatccgttc attattgttg taacaacgac aattcctttt tgtggagaaa
    18601 ttaacaaagc cgctccagat cgtgtgcata taattcagcg gctaccgatt gatagatctt
    18661 ccagtcaata aaattgccat cagggtagac ttgttgaaac gcggttaagt cggggaaaaa
    18721 acgcatggtg ttgttgccga tgcggttatt tattttctct atgatggcat gaagatgttt
    18781 ttttcgttgc tgacgcatag ccaacagttg ctcgactaca cgatcaggaa tggcgcattt
    18841 gccattttcc cactgacgcc agctttcact gtcaccggtc tgggcaatcc aggtcgcgca
    18901 ttcatcaata gtcatggcaa aaatatggcg aagtgcctgg agttcataag cgttcatcgt
    18961 gtaatggctg catgaaataa acaataaaat ataaataaca ttatcagcct gctgacggct
    19021 tgaagagagt cacagtatct tgtgcaacat tattggaaag agtgaggggc gaggtagcga
    19081 agcggaaaaa tgttaaaaaa aagcccatcg tgggagatgg gcaaagacta cacacagcaa
    19141 ttcgttgttt cactcagggg atttccatgc ttataaatca atatgttgat ttataaccgt
    19201 aagctaatag taggcatacg gactttttgc gtcgatcaga ttcgtctcat tagtttaaaa
    19261 actgtaaaga atttgcgaca ggtactacca gctgaatggc ggtaagcagg aaaatatggg
    19321 gaagagcaat caaatatcaa ttagcggggg ttaacaatca ggcggcagag ccgcctgatg
    19381 agaaattact tattcggttt ctcgatttcg ccaagttctt cgagaatttc ttccggttgg
    19441 tccgtcggcg gcgggacttc ttccacccac gcggcaaaca gacgccagga aacggctaac
    19501 agaaccggac caataaacag accgatcatc ccgaaagcaa tcaaaccacc aataacacca
    19561 gagaggatca ggatcagcgg taaatcggca cccatgcgaa ttaacattgg gcggatgacg
    19621 ttatccagcg tgccaaccac accgctccac actaacaata ccgttcccca ggtggtatcg
    19681 ccagtccagt agagccagat aatcgccgga atcagtaccg gcaacgggcc aagttggaca
    19741 aggcaggaga ggatcattaa caccgttagc aacgttgcat aaggtacgcc ggatacggcg
    19801 aggccgatac cgccaagcac tgcctgtact aacgccgtca ccaccacacc cagcgccacc
    19861 gcgcggatag cctgtgccgc cagcagtacg gcggcatctc cgcgaacgcc tgccagacgg
    19921 gttgcaaaat ggcgaatgcc ttgtgccacc tgttcaccgc gccagtacag cagggcactg
    19981 aagagaagca tcagcgcaca atgcaccata aagcgcccga tatgcgccgc ctgcccaacg
    20041 aaccaggtgg tggtggtgcc aatataaggg cggactttcg ccatgatcgc cgtccccccc
    20101 atatccagca agttgtgcca gcctgcatac agcttcgcgc caatcaccgg aatggtatta
    20161 agccacgcca gatcgggtaa cgtcatgtcg ccgctggaaa tggctttaat tagcgggccg
    20221 ctgccgtcga cgatactgtt aaccagcaaa gcaataggga tgataaacac catcactaat
    20281 aacagcgtca tcaccagaac ggcgagagag cggcggccaa acatgatctt ttgcaaacgt
    20341 aacaataccg gccaggtggc gataaccacc gtaccggccc atgcaaagcc gagaataaag
    20401 ggttgaacaa tccacagaca tgccacaatc atgatggcta aaaacagcac cgaaagcaga
    20461 atttgtgcga catccctggg ctgacgaaca tttaccataa ctacttttca ccttttttgt
    20521 gcgtcaaatc gtcgacgcga cgtgaacacg cgaaactcac ctgcataatg atgagcaatt
    20581 tcagcggttt ttaacaggcc gattctgccc ttaattctga tgggcgtgtt agaaaaaaat
    20641 gtggtacaac aactcaggca acacgcaaac gatttactcg tcgtatttca agttgcatgt
    20701 gctgcggcta cgttcgttca ccccagtcac ttactattgt aagctcctgg agttcactcg
    20761 cttgccgcct tcctgcaact cgaaatccat agagtaaata aacatcacct ttcagtacgc
    20821 tattgcagcc gcctgaaaga atagtgtatc gacctacatc acagaccgca ggaaagggtc
    20881 aatataatga ttccacagat ttcccaggca cccggcgtcg ttcaactggt gcttaatttt
    20941 ttgcaagagc tggagcaaca aggttttacc ggcgatacgg cgacaagtta tgccgatcgt
    21001 ctgacaatgt cgaccgacaa cagtatttac caacttctcc ccgatgcggt ggtatttccg
    21061 cgttcaaccg cagatgtggc gctgatcgcc cgtcttgccg cgcaggaacg ctactcatcg
    21121 ctgatcttta ccccccgcgg cggcggcacc ggcactaacg gtcaggcgct caaccagggg
    21181 attattgttg atatgtcccg ccatatgaac cgcatcatcg aaattaaccc tgaagagggc
    21241 tgggtgcgcg ttgaggccgg ggtgataaaa gatcaactca atcagtacct gaaaccgttc
    21301 ggctactttt ttgcgccgga actttcgacc agcaaccggg caacgctcgg tgggatgatc
    21361 aataccgatg catccggtca gggatcgctg gtctatggca aaacgtcaga tcacgtactt
    21421 ggcgtacgcg cggtgttgtt ggggggcgat attctcgata cgcaaccttt acccgtcgaa
    21481 ttggcggaaa cgctgggtaa atccaatacc acaatcgggc gaatttataa cacggtttat
    21541 caacgttgcc gtcagcaacg ccagttaatc atcgacaact tccccaaact taaccgcttt
    21601 cttaccggtt acgatctgcg tcatgtcttt aacgatgaga tgaccgagtt cgacctgacg
    21661 cgcattctga cgggttcaga agggacgctg gcctttatta ccgaagcgcg gctggatatt
    21721 acgcccttgc ctaaagtgcg ccgtctggtg aacgtcaaat atgactcttt tgactccgcg
    21781 ctgcgtaacg cgccgtttat ggttgaggcg cgggcgcttt cggtagagac ggtggactca
    21841 aaagtgctga atctggcgcg ggaagatatt gtctggcatt ccgtcagcga gttgattacc
    21901 gatgtgcctg acaaagagat gctcgggctg aacattgtgg agtttgctgg tgatgatgag
    21961 gcgctgattg atgagcgggt aaatgcactc tgtgcgcggt tggatgagct gatcgccagt
    22021 catcaagcag gtgtcatcgg ctggcaggtg tgccgtgagc tggcgggggt tgaacgtatc
    22081 tatgcaatgc gcaaaaaagc cgttggtctg cttggcaatg ccaaaggtgc cgctaagcca
    22141 attccgtttg ctgaggatac ctgcgtaccg ccggaacatc tggccgatta tattgctgaa
    22201 tttcgcgcgc tgctcgacag ccacggctta agctacggta tgttcggtca cgtcgacgca
    22261 ggtgtcttgc acgtccgtcc ggcactggat atgtgcgatc ctcaacaaga gattttgatg
    22321 aagcaaattt ctgatgacgt ggtggcgctg actgcgaaat acggtggttt gttgtggggc
    22381 gagcacggca aaggttttcg cgctgaatac agcccggcgt ttttcggtga ggaactttat
    22441 gcagaactgc gcaaagtgaa agcggcattt gacccgcata accgactcaa cccagggaag
    22501 atttgcccgc cagaaggtct cgatgcgccg atgatgaaag tggacgcggt gaagcgcggt
    22561 acattcgatc ggcagatccc cattgcggta cgccagcagt ggcgcggtgc gatggagtgt
    22621 aacggcaacg gtttatgctt caactttgat gcccgtagtc cgatgtgtcc gtcgatgaag
    22681 atcacccaga accggattca ttcaccgaaa gggcgcgcaa cgctggtgcg tgaatggctg
    22741 cgtttgttgg cggatcgcgg cgttgatcca ctcaaactgg aacaagaact gcctgaatcc
    22801 ggcgtcagtt tgcggacgtt aattgcccgc acgcgcaata gctggcatgc gaataaaggc
    22861 gaatatgact tctcacacga agtcaaagag gcgatgtcgg gctgtctggc ctgtaaagct
    22921 tgttcgaccc agtgccccat caaaattgat gtgccggagt ttcgctctcg tttcctgcag
    22981 ctctatcata cccgttattt acgtccgctg cgcgaccacc tcgtcgctac ggtcgagagc
    23041 tacgcgccgc tgatggcacg cgcgccgaaa acctttaact tcttcattaa ccagccgctg
    23101 gtgcgcaaac tctcggaaaa acatatcggc atggttgatt tgccactgct gtcggtcccc
    23161 tcgctacaac aacaaatggt ggggcatcgc tcggcaaaca tgacgctgga acagcttgaa
    23221 gctctcaatg cagagcagaa agcgcgcacg gtgttggtgg tgcaggaccc ctttaccagc
    23281 tattacgatg cgcaagtggt ggcggatttt gtccgtctgg ttgaaaaatt aggtttccag
    23341 ccggtgttac tgccattttc gccaaatggc aaagcccagc atattaaagg ttttcttaat
    23401 cgttttgcga agacggcgaa aaagacggcg gatttcctca accgtatggc gaagctgggg
    23461 atgccaatgg tgggcgtcga tccggcgctg gtactttgtt atcgcgatga atataaactg
    23521 gcgctgggcg aggaacgtgg cgagtttaac gtcttactgg cgaatgaatg gctggcaagc
    23581 gcacttgagt cacagccagt ggctacagtc agcggtgaat catggtattt ctttggtcac
    23641 tgtaccgagg ttaccgcctt gccgggcgcg ccagcacaat gggccgcgat atttgcccgt
    23701 tttggcgcga aactggaaaa tgtcagcgtg ggttgctgcg gcatggcagg gacttacgga
    23761 catgaagaga aaaaccataa aaattcgctc gggatctatg agttatcctg gcatcaggct
    23821 atgcagcgac tgccgcgtaa ccgctgtctg gcgaccggat attcctgccg tagccaggtc
    23881 aaacgggttg aaggcacggg ggtacgccat cctgtgcagg ctttactgga gattattaaa
    23941 tgatatggaa acgaaaaatc accctggaag cactgaatgc tatgggtgaa ggaaacatgg
    24001 tggggttgct ggatattcgc tttgaacata ttggtgatga cacccttgaa gcgacaatgc
    24061 cagtagactc gcggacaaag cagcctttcg ggttgctgca tggaggcgca tccgtggtgc
    24121 tggccgaaag tatcggttcc gttgccggtt atttatgtac tgaaggtgag caaaaagtgg
    24181 ttggcctgga aatcaatgct aaccacgtcc gctcggcacg agaagggcgg gtgcgcggcg
    24241 tatgcaaacc gttgcatctc ggttcgcgtc accaggtctg gcagattgaa atcttcgatg
    24301 agaaagggcg tttgtgctgt tcgtcacgat tgacgaccgc cattttgtga cgttgtcacc
    24361 agaaaagtgt gacgcatatt gcttttggtc attatctgca cagtaaacgg tggtatactg
    24421 tgcaggtctt gtctaaaagc gaggatgcta tgtctactca acttgatccc acccagctgg
    24481 ccattgaatt tttacgccgt gaccagagca atctttcacc tgcccaatat ctcaaacgtc
    24541 tgaaacaact agaacttgaa tttgctgacc tgcttactct ctcttctgct gaattaaaag
    24601 aagaaatcta ctttgcctgg cgtctgggcg tgcattgatc ctgacttaat gccgcaagtt
    24661 cgccaaatcg acctggatta acctccgtcc aggttcgatg accttcttaa tactgcttat
    24721 ctacccgcct gatattgttc aaaaataata ctaatcgcag tttgtgttaa aacggcgggt
    24781 tagctttatg agattattct tatcgcccct tcaagagcta agccactgag agtgccggag
    24841 ataagcgccg gatggggtag aaacccttaa gcctgtgtcg cacagactta agggttttct
    24901 tatttctgaa cgctgcactt ttttacctat ctcttaaata gtcattttca atacaacttt
    24961 ttctttttca tcacagcctt aatgctcctt agataataac cattatctaa caatgagata
    25021 cctaattctt agcgtgcctg ttaacccaca catcagggtc tatgcttatt aaaagcaggc
    25081 aaaaagcatg ttttacggta aagcccctgc gtttgctggg ttgaactgat aatcattatc
    25141 actaacatgc tgttatacgc tgaaagcgat gaagtgaggt aaatcgatgg acatgcattc
    25201 aggaaccttt aacccacaag atttcgcctg gcaaggctta acgctgacac ccgcagcggc
    25261 gatacacatc cgtgagctgg tggcaaagca gccgggtatg gtcggcgtgc gcttaggcgt
    25321 gaagcaaacg ggctgcgcgg gctttggcta tgtgctcgac agtgttagcg agccggacaa
    25381 agacgatctg ctgtttgaac acgacggcgc gaagctgttt gtcccgctgc aagcgatgcc
    25441 gtttattgat ggcacggaag tcgatttcgt tcgtgaagga cttaatcaga tattcaaatt
    25501 tcacaaccct aaagcccaga atgaatgtgg ctgtggcgaa agctttgggg tataggcggt
    25561 actatgtctc gtaatactga agcaactgac gatgtcaaaa catggaccgg cggcccgctg
    25621 aattataaag aaggattctt cacccagtta gccaccgatg agctggcaaa ggggataaac
    25681 gaagaggtgg tgcgcgcaat ttcggcgaag cgtaatgagc cggagtggat gctggagttt
    25741 cgtctaaacg cctatcgcgc atggctggag atggaagaac cgcactggtt gaaagcgcac
    25801 tacgacaagc tgaattatca ggattacagc tactactcag caccatcgtg cggtaattgt
    25861 gacgacactt gcgcgtctga acctggcgcg gtgcagcaaa ctggcgcgaa cgccttttta
    25921 agtaaagagg tggaggcggc gtttgagcag ttgggcgttc ccgtgcggga aggcaaagag
    25981 gtggcggtgg atgccatttt cgactctgtt tcggttgcca ctacttatcg cgaaaaactg
    26041 gcggagcagg gaattatttt ctgttccttt ggtgaggcga tccacgatca cccggaactg
    26101 gtgcgtaaat atctcggcac cgtggtgccg gggaatgaca acttctttgc cgcgcttaat
    26161 gcggcggtag cctctgacgg tacgtttatt tatgtgccta aaggcgtgcg ctgcccgatg
    26221 gaactttcca cctattttcg cattaacgcg gaaaaaactg ggcagtttga gcgcaccatt
    26281 ctggtggccg acgaagacag ctacgtcagc tacattgaag gctgttccgc tccggtgcgt
    26341 gacagctatc agttacacgc ggcagtggtg gaagtcatca tccataaaaa cgccgaggtg
    26401 aaatattcca cggtacaaaa ctggttccct ggcgataaca acaccggcgg tattctcaac
    26461 ttcgtcacca agcgtgcttt gtgcgaaggc gaaaacagca aaatgtcatg gacgcaatca
    26521 gaaaccgggt cagcgattac gtggaaatat cccagctgca ttttgcgcgg cgataactcc
    26581 attggtgagt tttactcagt ggcgctgacc agcggtcatc agcaagcgga taccggcacc
    26641 aagatgatcc acatcggtaa aaacaccaaa tcgaccatta tctcgaaagg gatctctgcc
    26701 ggacatagtc agaacagtta tcgcggctta gtgaaaatca tgccgacggc aaccaatgcg
    26761 cgcaatttca ctcagtgcga ctcaatgctg attggcgcta attgtggggc gcataccttc
    26821 ccgtatgtcg aatgtcgcaa taacagcgca caactggagc acgaggcaac gacatcacgt
    26881 attggtgaag atcaactgtt ttactgcctg caacgcggga tcagcgaaga agacgccatc
    26941 tcgatgattg ttaacggttt ctgcaaagac gtgttctcag aactgccgct ggaatttgcc
    27001 gttgaagcac aaaaactcct cgccatcagt cttgaacaca gcgtcggata aggaataaac
    27061 atgttaagta ttaaagattt acacgtcagc gtggaagata aagctatcct gcgtggatta
    27121 agcctcgacg ttcgtcccgg cgaagttcac gccattatgg ggccaaacgg ttcgggcaaa
    27181 agtaccttat cggcaacgct tgccgggcga gaagattatg aagtgacggg cggcacggtt
    27241 gagttcaaag gcaaagattt gcttgcgctg tcgccggaag atcgtgcagg cgaaggcatc
    27301 tttatggcct tccagtatcc ggtggagatt cccggcgtca gtaaccagtt tttcctgcaa
    27361 acggcactta atgcggtgcg cagctatcgc ggccaggaaa cgctcgaccg ctttgatttt
    27421 caggatttga tggaagagaa aatcgctctc ctgaagatgc cggaagattt attaacccgt
    27481 tcggtaaacg ttggtttttc cggcggcgag aaaaagcgca acgatatttt gcaaatggcg
    27541 gtgctggaac cggagttatg cattcttgat gagtcggact ccgggctgga tattgacgca
    27601 ttaaaagtgg tcgccgatgg cgtgaactcg ctgcgtgatg gcaagcgctc attcatcatt
    27661 gttacgcact accaacgcat tctcgactac atcaagcctg attacgttca tgtgctatat
    27721 cagggacgaa ttgtgaaatc cggcgatttc acgttggtca aacaactgga ggagcagggt
    27781 tatggctggc ttaccgaaca gcagtaatgc gctgcaacag tggcatcact tgtttgaagc
    27841 tgaagggaca aaacgctcac cgcaagcaca gcagcattta caacaattgc tgcgtaccgg
    27901 actgccgaca cgtaaacatg aaaactggaa atatacgccg ctggaagggc tgaccaatag
    27961 ccagtttgtc agcattgcgg gagagatatc cccacagcag cgagatgcct tagcgttaac
    28021 gttagacgct gtgcggctgg tatttgtcga tggacgttac gtgtcagcac tgagcgatgc
    28081 gactgaaggc agcgggtatg aagtgagcat taacgacgac cgtcaggggg tacccgacgc
    28141 tattcaggcg gaagtgtttc tgcatttgac ggaaagcctg gcacaaagcg tgacgcatat
    28201 cgccgtgaag cgcggtcaac ggccggcaaa gccattgctg ttaatgcata ttacccaggg
    28261 cgtggcaggt gaagaggtca acactgccca ttaccgacat catctggatc tggcggaagg
    28321 tgccgaagca acggtgatcg aacattttgt cagccttaat gatgctcgtc acttcaccgg
    28381 cgcacggttc actatcaatg tcgcagcgaa cgcccacttg cagcatatca agctggcgtt
    28441 tgaaaacccg gtcagtcacc actttgccca taacgatttg ttgctggctg acgatgccac
    28501 cgcatttagc catagtttcc tgctgggtgg cgcagtgtta cgacacaaca ccagtacgca
    28561 actcaatggc gaaaacagca cgctgcggat caatagcctg gcgatgccgg tgaaaaacga
    28621 ggtgtgtgat acccgtacct ggctggaaca caataaaggt ttttgtaaca gccgacagtt
    28681 gcacaaaact atcgtcagcg acaaaggccg cgcggtattt aacggtttga tcaacgtcgc
    28741 gcagcacgcc atcaaaacgg atggtcagat gaccaacaat aatctgctga tgggcaaact
    28801 ggcggaagtg gatacaaaac cgcagctgga aatctatgca gatgatgtga aatgcagcca
    28861 cggcgcgacg gtggggcgta ttgatgatga acagatgttc tatctgcgct cgcgcgggat
    28921 caatcagcag gatgcccagc agatgatcat ttacgccttt gctgccgaac tgacggaagc
    28981 actgcgtgat gaggggctta aacagcaggt gctggcccga atcggtcaac ggctgccagg
    29041 aggtgcaaga tgactttttc cgtcgacaaa gtgcgggccg actttccggt gctttcgcgt
    29101 gaggtaaacg gtttgccgct ggcttatctc gacagcgccg ccagtgcaca gaaaccgagc
    29161 caggtgattg acgccgaggc cgagttttat cgtcatggct acgcggcggt gcatcgcggt
    29221 attcatacct taagcgctca ggcgaccgag aaaatggaga acgtgcgcaa gcgggcatcg
    29281 ctgtttatta atgcccgttc ggcggaagag ctggtgttcg tccgcggcac gacggaaggg
    29341 atcaatctgg tcgccaatag ctggggcaac agcaatgtgc gggcgggcga taacatcatc
    29401 atcagtcaga tggagcacca cgctaacatt gtcccctggc agatgctttg cgcacgcgtt
    29461 ggcgcagagc tgcgtgtgat ccctctcaac cccgacggta cgctgcaact ggagacgctg
    29521 cctacgctgt ttgatgagaa aactcgcctg ctggcaatta ctcatgtctc caacgtgctg
    29581 ggaacagaaa atccgctggc ggaaataatc acgcttgcgc accagcatgg cgcaaaagtg
    29641 ctggtggatg gcgctcaggc ggtgatgcat catccggtgg atgttcaggc gctggattgc
    29701 gacttttacg tgttctccgg gcataaactg tatggcccca ccggaattgg cattctttat
    29761 gtgaaagaag ccttgttgca ggagatgccg ccgtgggaag ggggcggttc tatgatcgcc
    29821 accgtcagcc tgagtgaagg cactacctgg accaaagcac catggcggtt tgaagccggt
    29881 acacccaata ccgggggcat cattggtctt ggcgcggcgc tggagtatgt ttcggcgctg
    29941 gggcttaata gcatagccga gtatgaacag aatctgatgc attatgcgct atcacagctg
    30001 gaatctgtac cggatctcac tctctatggc ccacaaaaca ggcttggcgt tattgctttt
    30061 aatctcggta aacaccacgc ctatgatgtt ggcagttttc tcgataatta cggcattgct
    30121 gtgcgtaccg gacatcactg cgctatgcca ttaatggcct attacaacgt ccctgcgatg
    30181 tgtcgggcgt cgctggccat gtataacacc catgaagaag tggatcgtct ggtgaccgga
    30241 ctgcaacgta ttcaccgtct gctgggataa cagggaggca ctatggcttt attgccggat
    30301 aaagaaaaat tgctgcgtaa ttttttacgc tgcgccaatt gggaagagaa atatctctac
    30361 attattgagc tgggccagcg tctgccagaa ttacgcgacg aagaccgaag cccacaaaat
    30421 agcattcagg gctgccagag tcaggtgtgg attgtcatgc gccagaatgc gcagggaatt
    30481 attgaattgc agggcgacag cgatgcggcg attgtgaaag ggcttattgc ggtcgtattt
    30541 attctctacg atcagatgac gccgcaggat attgtcaatt tcgatgtgcg tccgtggttt
    30601 gaaaaaatgg cgctcaccca acatctcacc ccatctcgtt cacaaggtct ggaagcgatg
    30661 attcgcgcaa ttcgcgccaa agccgctgca cttagctaaa ctaaagggac agctttcatc
    30721 cggttggctc acattgccgg atggtcaatg tttacactga cctgcacagg agtgttttgg
    30781 tttcaggtga acataagcgc catccgacgt ttcagcgtga gtctccggca aatacaggag
    30841 gtttacaatg aaacgcgcgt ctttgcttac actcacgctt atcggcgctt ttagcgccat
    30901 ccaggctgcc tgggcggttg attatccgct accaccaacc ggaagccgac tggttgggca
    30961 aaatcaaacg tatacggtgc aagaagggga taaaaacctt caggctattg cccgacgttt
    31021 tgatactgcg gcaatgttga tccttgaagc caataacact atcgccccgg tgccaaaacc
    31081 tggtacgacg ataactattc cttcacaact gttattacct gatgcaccgc gtcaggggat
    31141 tatcgttaac cttgcagagc tgcgccttta ttattatccg ccgggagaaa atattgtgca
    31201 ggtttatcca ataggtattg gattgcaggg gctggaaacg ccggtgatgg aaacgcgtgt
    31261 tgggcagaaa atccctaacc caacctggac gcctacggca ggcattcgtc aacgttcgct
    31321 ggagcgtggc attaaattac cgccagtcgt tcctgccgga ccaaataacc cgctaggacg
    31381 ttacgcactg cgcctcgcgc atggtaatgg cgaatacctc attcatggta ccagtgcgcc
    31441 ggacagcgtc ggtttgcgcg tcagttcagg gtgtattcgc atgaatgcac cggatattaa
    31501 agccttgttc tccagcgtgc ggacgggaac gccggtgaaa gtgatcaacg aaccggtgaa
    31561 atattccgtg gaacctaacg ggatgcgtta tgttgaagta catcgaccac tatcagcaga
    31621 agaacagcaa aacgttcaga caatgccata cacactgcca gcaggcttta cgcaatttaa
    31681 agacaataag gctgtagatc agaagttagt cgataaagcg ttgtatcgtc gggcagggta
    31741 tccggtttcg gtgagcagtg gagcaactcc cgcagccagc aatgcgcctt cagtagagtc
    31801 agcgcagaat ggtgaaccag agcaagggaa tatgttacgc gcgacgcagt agcggtaaac
    31861 ggcagacaaa aaaaatggcg cacaatgtgc gccatttttc acttcacagg tactattact
    31921 tgcggtattt agtagccatg ttgtccagac gctggttagc acgagctgcg tcatctttag
    31981 cagcctgaac gtcggaacgc attgcgttca cgtcgttgct cagctggtca actttagcgt
    32041 tcagagtctg aacgtcagaa gacagctgat cgattttagc gttgctggag caacctgcca
    32101 gcagagtaga acccaggatt accgcgccca gtaccagttt agtagctttc attattaata
    32161 ccctctagat tgagttaatc tccatgtagc gttacaagta ttacacaaag ttttttatgt
    32221 tgagaatatt tttttgatgg gaaggcactt atttttgatc gttcgctcaa agaagcatcg
    32281 aacgctgggt tttagataaa aaaattgaga gaaa
//
LOCUS       DAPGUL010000048        31671 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.048, whole genome shotgun sequence.
ACCESSION   DAPGUL010000048 DAPGUL010000000
VERSION     DAPGUL010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 31671)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31671)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31671
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.048"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(145..1086)
                     /gene="fabY"
                     /locus_tag="RHX21_002355"
                     /gene_synonym="yiiD"
     CDS             complement(145..1086)
                     /gene="fabY"
                     /locus_tag="RHX21_002355"
                     /gene_synonym="yiiD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001666856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid biosynthesis protein FabY"
                     /protein_id="HDV1987525.1"
                     /translation="MYHLRVPQTEEELERYYQFRWEMLRKPLHQPKGSERDAWDAMAH
                     HQMVVDEQGNLVAVGRLYINADNEASIRFMAVHPDVQDKGLGTLMAMTLESVARQEGV
                     KRVTCSAREDAVEFFAKLGFVNQGEITTPTTTPIRHFLMIKPVATLDDILHRGDWCAQ
                     LQQAWYEHIPLSEKMGVRIQQYTGQKFITTMPETGNQNPHHTLFAGSLFSLATLTGWG
                     LIWLMLRERHLGGTIILADAHIRYSKPISGKPHAVADLGALSGDLDRLARGRKARVQM
                     QVEIFGDETPGAVFEGTYIVLPAKPFGPYEEGGNEEE"
     gene            complement(1131..1568)
                     /gene="dtd"
                     /locus_tag="RHX21_002356"
     CDS             complement(1131..1568)
                     /gene="dtd"
                     /locus_tag="RHX21_002356"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HDV1987526.1"
                     /translation="MIALIQRVTRASVTVEGEVTGEIGAGLLVLLGVEKDDDEQKANR
                     LCERVLGYRIFSDAEGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSKGASPDRA
                     EALYDYFVERCRQQEMNTQTGRFAADMQVSLVNDGPVTFWLQV"
     gene            complement(1565..2437)
                     /locus_tag="RHX21_002357"
     CDS             complement(1565..2437)
                     /locus_tag="RHX21_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor BrkB family protein"
                     /protein_id="HDV1987527.1"
                     /translation="MLKTIQDKARHRTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSL
                     LSLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFLPATGDVIQRYIEQFVANSNKMT
                     AVGACGLIVTALLLMYSIDSALNTIWRSKRARPKIYSFAVYWMILTLGPLLAGASLAI
                     SSYLLSLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAA
                     LLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYR
                     KLKQAAEQEEDDEP"
     gene            complement(2431..3030)
                     /gene="yihX"
                     /locus_tag="RHX21_002358"
     CDS             complement(2431..3030)
                     /gene="yihX"
                     /locus_tag="RHX21_002358"
                     /EC_number="3.1.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709685.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphatase"
                     /protein_id="HDV1987528.1"
                     /translation="MLYIFDLGNVIVDIDFNRVLGAWSDLTRIPLASLKKSFHMGEAF
                     HQHERGEISDEAFAEALCHEMALPLSYEQFSHGWQAVFVALRPEVIAIMHKLREQGHR
                     VVVLSNTNRLHTTFWPEEYPEIRDAADHIYLSQDLGMRKPEARIYQHVLQAEGFSPSD
                     TVFFDDNADNIEGANQLGITSILVKDKTTIPDYFAKVLC"
     gene            complement(3129..3914)
                     /locus_tag="RHX21_002359"
     CDS             complement(3129..3914)
                     /locus_tag="RHX21_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418320.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDV1987529.1"
                     /translation="MSLTELTGNPRHDQLLMLIAERGYMNIDELANLLDVSTQTVRRD
                     IRKLSEQGLITRHHGGAGRASSVVNTAFEQREVSQTEEKKAIAEAVADYIPDGSTIFI
                     TIGTTVEHVARALLNHNHLRIITNSLRVAHILYHNPRFEVMVPGGTLRSHNSGIIGPS
                     AASFVADFRADYLVTSVGAIESDGALMEFDVNEANVVKTMMAHARNILLVADHTKYHA
                     SAAVEIGNVAQVTALFTDELPPAALKSRLQDSQIEIILPQEDA"
     gene            complement(3948..4844)
                     /gene="yihV"
                     /locus_tag="RHX21_002360"
     CDS             complement(3948..4844)
                     /gene="yihV"
                     /locus_tag="RHX21_002360"
                     /EC_number="2.7.1.184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418319.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfofructose kinase"
                     /protein_id="HDV1987530.1"
                     /translation="MIRVACVGITVMDRIYYVEGLPTESGKYVARNYTEVGGGPAATA
                     AVAAARLGAQVDFIGRVGDDDTGNSLLAELESWGVNTRYTKRYNQAKSSQSAIMVDTK
                     GERIIINYPSPDLLPDAEWLEEIDFSQWDVVLADVRWHDGAKKAFTLARQAGVMTVLD
                     GDITPQDISELVALSDHAAFSEPGLARLTGVKEMASALKQAQTLTNGHVYVTQGSAGC
                     DWLENGGRQHQPAFKVDVVDTTGAGDVFHGALAVALATSGDLAESVRFASGVAALKCT
                     RPGGRAGIPDCDQTRSFLSLFV"
     gene            5012..5908
                     /gene="yihU"
                     /locus_tag="RHX21_002361"
     CDS             5012..5908
                     /gene="yihU"
                     /locus_tag="RHX21_002361"
                     /EC_number="1.1.1.373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfolactaldehyde 3-reductase"
                     /protein_id="HDV1987531.1"
                     /translation="MAAIAFIGLGQMGSPMASNLLQQGHQLRVFDVNAEAVRHLVDKG
                     ATPAANPAQAAKDAEFIITMLPNGDLVRSVLFGENGVCESLSTDALVIDMSTIHPLQT
                     DKLIADMQAKGFSMMDVPVGRTSANAITGTLLLLAGGTAEQVERATPILMAMGSELIN
                     AGGPGMGIRVKLINNYMSIALNALSAEAAVLCEALNLPFDVAVKVMSGTAAGKGHFTT
                     SWPNKVLSGDLSPAFMIDLAHKDLGIALDVANQLHVPMPLGAASREVYSQARAAGRGR
                     QDWSAILEQVRVSAGMTAKVKM"
     gene            5932..6810
                     /gene="yihT"
                     /locus_tag="RHX21_002362"
     CDS             5932..6810
                     /gene="yihT"
                     /locus_tag="RHX21_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfofructosephosphate aldolase"
                     /protein_id="HDV1987532.1"
                     /translation="MNKYTINDITRASGGFAMLAVDQREAMRMMFAAAGAPAPVADSV
                     LTDFKVNAAKALSPYASAILVDQQFCYRQVVEQNAIAKSCAMIVAADEFIPGNGIPVD
                     SVVIDRKINPLQIKQDGGKALKLLVLWRSDEDAQQRLDMVKEFNELCHSHGLVSIIEP
                     VVRPPRRGDKFDREQAIIDAAKELGDSGADLYKVEMPLYGKGPQQELLCASQRLNDHI
                     NMPWVILSSGVDEKLFPRAVRVAMTAGASGFLAGRAVWASVVGLPDNELMLRDVCAPK
                     LQQLGDIVDEMMAKRR"
     gene            6827..8068
                     /gene="yihS"
                     /locus_tag="RHX21_002363"
     CDS             6827..8068
                     /gene="yihS"
                     /locus_tag="RHX21_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418316.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfoquinovose isomerase"
                     /protein_id="HDV1987533.1"
                     /translation="MKWFNTLSHNRWLEQETDRIFDFGKNSVVPTGFGWLGNKGQIKE
                     EMGTHLWITARMLHVYSVAAAMGRPGAYSLVDHGIKAMNGALRDKKYGGWYACVNDEG
                     VVDASKQGYQHFFALLGAASAVTTGHPEARKLLDYTIEIIEKYFWSEEEQMCLESWDE
                     AFSKTEEYRGGNANMHAVEAFLIVYDVTHDKKWLDRAIRVASVIIHDVARNNHYRVNE
                     HFDTQWNPLPDYNKDNPAHRFRAFGGTPGHWIEWGRLMLHIHAALEARCEQPPAWLLE
                     DAKGLFNATVRDAWAPDGADGIVYTVDWEGKPVVRERVRWPIVEAMDTAYALYTVTGD
                     RQYETWYQTWWEYCIKYLMDYENGSWWQELDADNKVTTKVWDGKQDIYHLLHCLVIPR
                     IPLAPGMAPAVAAGLLDINAK"
     gene            8206..9108
                     /locus_tag="RHX21_002364"
     CDS             8206..9108
                     /locus_tag="RHX21_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709679.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose-1-epimerase"
                     /protein_id="HDV1987534.1"
                     /translation="MQITNMHCSGQTVSLAAGDYHATIVTVGAGLAELTFQGCHLVIP
                     HKPEEMPLAHLGKVLIPWPNRIANGCYRYQGQEYQLPINEHSSKAAIHGLLAWRDWQI
                     SELTATSVTLTAFLPPSYGYPFMLASQVVYSLNAHTGLSVEIASQNIGTVAAPYGVGI
                     HPYLTCNLTSVDEYLFQLPANQVYAVDEHANPTTLHHVDELDLNFTQAKKIAATKIDH
                     TFKTANDLWEMTITHPQQALSVSLCSDQLWVQVYSGEKLQRQGLAVEPMSCPPNAFNS
                     GIDLLLLESGKPHRLFFNIYGQRK"
     gene            9307..11343
                     /gene="yihQ"
                     /locus_tag="RHX21_002365"
     CDS             9307..11343
                     /gene="yihQ"
                     /locus_tag="RHX21_002365"
                     /EC_number="3.2.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfoquinovosidase"
                     /protein_id="HDV1987535.1"
                     /translation="MDTPRPQLLDFQFHQNNDSFTLHFQQRLILTHSKDNPCLWIGSG
                     IADIDMFRGNFSIKDKLQEKIALTDAIVSQSPDGWLIHFSRGSDISATLNISADDQGR
                     LLLELQNDNLNHNRIWLRLAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQ
                     TYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALW
                     EDKATLRFECADTYISLLEKLTALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMR
                     NAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSENYPQLDSCIKQWNQEGVQFLAYI
                     NPYVASDKDLCEEAAKRGYLAKDAAGGDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKK
                     NMIELGCGGWMADFGEYLPTDTYLHNGVSAEIMHNAWPALWAKCNYEALEETGKLGEI
                     LFFMRAGSTGSQKYSTMMWAGDQNVDWSLDDGLASVVPAALSLAMTGHGLHHSDIGGY
                     TTLFEMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFARMTSVFT
                     TLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAHTYTLKYQYLLGRDILVAPVHEEGRS
                     DWTLYLPEDNWVHAWTGEAFRGGEVTVNTPIGKPPVFYRADSEWAALFASLKSI"
     gene            11389..12774
                     /locus_tag="RHX21_002366"
     CDS             11389..12774
                     /locus_tag="RHX21_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1987536.1"
                     /translation="MSHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFY
                     TDVLGLPGTYGGIIFLISKFFTAFTDMGTGIMLDSRRKIGPKGKFRPFILYASFPVTL
                     LAIANFVGTPFDVTGKTVMATILFMLYGLFFSMMNCSYGAMVPAITKNPNERASLAAW
                     RQGGATLGLLLCTVGFVPVMNLIEGNQKLGYIFAATLFSLFGLLFMWICYSGVKERYV
                     ETQPTNPAQKPGLLQSFRAIAGNRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLNDP
                     ILLSYMGFFSMGCIFIGVFLMPGAVRRFGKKKVYIGGLLIWVLGDLLNYFFGGGSVSF
                     VAFSCLAFFGSAFVNSLNWALVSDTVEYGEWRTGVRSEGTVYTGFTFFRKVSQALAGF
                     FPGWMLTQIGYVPNVAQADHTIEGLRQLIFIYPSALAVVTIVAMGCFYSLNEKMYVRI
                     VEEIEARKRTA"
     gene            12817..14220
                     /locus_tag="RHX21_002367"
     CDS             12817..14220
                     /locus_tag="RHX21_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1987537.1"
                     /translation="MSDHNPLTLKLNLREKIAYGMGDVGSNLMLCIGTLYLLKFYTDE
                     LGMPAYYGGIIFLVAKFFTAFTDMLTGFLLDSRKNIGPKGKFRPFILYAAVPAALIAT
                     LQFIATTFCLPVKTTIATALFMMFGLSYSLMNCSYGAMIPAITKNPNERAQLAAYRQG
                     GATIGLLICTVAFIPLQSLFSDSTVGYACAALMFSIGGFIFMMLCYRGVKEHYVDTTP
                     TGHKASILKSFCAIFRNPPLLVLCIANLCTLAAFNIKLAIQVYYTQYVLNDINLLSWM
                     GFFSMGCILIGVLLVPLTVKCFGKKQVYLAGMVLWAVGDILNYFWGSNSFTFVMFSCV
                     AFFGTAFVNSLNWALVPDTVDYGEWKTGIRAEGSVYTGYTFFRKISAALAGFLPGIML
                     TQIGYVPNIAQSDATLQGLRQLIFIWPCALAIIAALTMGFFYTLNEKRFALIIEEINQ
                     RKNKEMATEEKTASVTL"
     gene            14288..14980
                     /gene="ompL"
                     /locus_tag="RHX21_002368"
     CDS             14288..14980
                     /gene="ompL"
                     /locus_tag="RHX21_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpL"
                     /protein_id="HDV1987538.1"
                     /translation="MKKINAIILLSSLTSASVFAGAYVENREAYNLASDQGEVMLRVG
                     YNFDMGAGIMLTNTYNFQREDELKHGYNEIEGWYPLFKPTDKLTIQPGGLINDKSIGS
                     GGAVYLDVNYKFVPWFNLTVRNRYNHNNYSSTDLSGELDNNDTYEIGTYWNFKITDKF
                     SYTFEPHYFMRVNDFNSSNGKDHHWEITNTFRYRINEHWLPYFELRWLDRNVEPYHRE
                     QNQIRIGTKYFF"
     gene            complement(15071..16336)
                     /locus_tag="RHX21_002369"
     CDS             complement(15071..16336)
                     /locus_tag="RHX21_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1987539.1"
                     /translation="MLTKKKWALFSLLTLCGGTIYKLPSLKDAFYIPMQEYFHLTNGQ
                     IGNAMSVNSFVTTVGFFLSIYFADKLPRRYTMSFSLIATGLLGVYLTTMPGYWGILFV
                     WALFGVTCDMMNWPVLLKSVSRLGNSEQQGRLFGFFETGRGIVDTVVAFSALAVFTWF
                     GSGLLGFKAGIWFYSLIVIAVGIIIFFVLNDKEEAPSVEVKKEDGASKNTSMTSVLKD
                     KTIWLIAFNVFFVYAVYCGLTFFIPFLKNIYLLPVALVGAYGIINQYCLKMIGGPIGG
                     MISDKILKSPSKYLCYTFIISTAALVLLIMLPHESMPVYLGMACTLGFGAIVFTQRAV
                     FFAPIGEAKIAENKTGAAMALGSFIGYAPAMFCFSLYGYILDLNPGIIGYKIVFGIMA
                     CFAFSGAVVSVMLVKRISQRKKEMLAAEA"
     gene            complement(16438..17418)
                     /locus_tag="RHX21_002370"
     CDS             complement(16438..17418)
                     /locus_tag="RHX21_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM barrel protein"
                     /protein_id="HDV1987540.1"
                     /translation="MVTINNARKILQRVDTLPLYLHAYAFHLNMRLERVLPADLLDIA
                     SENNLRGVKIHVLDGERFSLGNMDDKELSAFGDKARRLNLDIHIETSASYKASIDEAV
                     AIALKTGASSVRFYPRYEGNLRDVLSIIANDIAYVRETYQDSGLTFTIEQHEDLKSHE
                     LVSLVKESEMESLSLLFDFANMINANEHPIDALKTMAPHITQVHIKDALIVKEQGGLG
                     HKACISGQGDMPFKALLTHLICLGDDEPQVTAYGLEEEVDYYAPAFRFEDEDDNPWIP
                     YRQMSETPLPENHLLDARLRKEKEDAINQINHVRNVLQQIKQEANHLLNH"
     gene            complement(17426..18136)
                     /locus_tag="RHX21_002371"
     CDS             complement(17426..18136)
                     /locus_tag="RHX21_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTRA domain-containing protein"
                     /protein_id="HDV1987541.1"
                     /translation="MAENQSTVENAKEKLDRWLKDGITTPGGKLPSERELGELLGIKR
                     MTLRQALLNLEAESKIFRKDRKGWFVTQPRFNYSPELSASFQRAAIEQGREPSWGFTE
                     KNRTSDIPETLAPLIAVTPSTELYRITGWGALEGHKVFYHETYINPEVAPGFIEQLEN
                     HSFSAVWEKCYQKETVVKKLIFKPVRMPGDISKYLGGSAGMPAILIEKHRADQQGNIV
                     QIDIEYWRFEAVDLIINL"
     gene            complement(18353..20176)
                     /gene="typA"
                     /locus_tag="RHX21_002372"
     CDS             complement(18353..20176)
                     /gene="typA"
                     /locus_tag="RHX21_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-dependent GTPase TypA"
                     /protein_id="HDV1987542.1"
                     /translation="MIEKLRNIAIIAHVDHGKTTLVDKLLQQSGTFDSRAETQERVMD
                     SNDLEKERGITILAKNTAIKWNDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAF
                     DGPMPQTRFVTKKAFAYGLKPIVVINKVDRPGARPDWVVDQVFDLFVNLDATDEQLDF
                     PIVYASALNGIAGLDHEDMAEDMTPLYQAIVDHVPAPDVDLDGPFQMQISQLDYNSYV
                     GVIGIGRIKRGKVKPNQQVTIIDSEGKTRNAKVGKVLGHLGLERIETDLAEAGDIVAI
                     TGLGELNISDTVCDTQNVEALPALSVDEPTVSMFFCVNTSPFCGKEGKFVTSRQILDR
                     LNKELVHNVALRVEETEDADAFRVSGRGELHLSVLIENMRREGFELAVSRPKVIFREI
                     DGRKQEPYENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIG
                     FRSEFMTMTSGTGLLYSTFSHYDDVRPGEVGQRQNGVLISNGQGKAVAFALFGLQDRG
                     KLFLGHGAEVYEGQIIGIHSRSNDLTVNCLTGKKLTNMRASGTDEAVVLVPPIRMTLE
                     QALEFIDDDELVEVTPTSIRIRKRHLTENDRRRANRAPKDD"
     gene            20549..21958
                     /gene="glnA"
                     /locus_tag="RHX21_002373"
     CDS             20549..21958
                     /gene="glnA"
                     /locus_tag="RHX21_002373"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--ammonia ligase"
                     /protein_id="HDV1987543.1"
                     /translation="MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFF
                     EEGKMFDGSSIGGWKGINESDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYD
                     RDPRSIAKRAEDYLRSTGIADTVLFGPEPEFFLFDDIRFGSSISGSHVAIDDIEGAWN
                     SSTQYEGGNKGHRPAVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAG
                     QNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLS
                     KNGVNLFAGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPGYEAPVMLA
                     YSARNRSASIRIPVVSSPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEA
                     MDKNLYDLPPEEAKEIPQVAGSLEEALNELDLDREFLKAGGVFTDEAIDAYIALRREE
                     DDRVRMTPHPVEFELYYSV"
     gene            22132..23181
                     /gene="glnL"
                     /locus_tag="RHX21_002374"
     CDS             22132..23181
                     /gene="glnL"
                     /locus_tag="RHX21_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulation protein NR(II)"
                     /protein_id="HDV1987544.1"
                     /translation="MATGTQPDAGQILNSLINSILLIDDNLAIHYANPAAQQLLAQSS
                     RKLFGTPLPELLSYFSLNIELMQESLEAGQGFTDNEVTLVIDGRSHILSVTAQRMPDG
                     MILLEMAPMDNQRRLSQEQLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLSKALP
                     DPSLLEYTKVIIEQADRLRNLVDRLLGPQLPGTRVTESIHKVAERVVTLVSMELPDNV
                     RLIRDYDPSLPELAHDPDQIEQVLLNIVRNALQALGPEGGEIILRTRTAFQLTLHGER
                     YRLAARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHSGKIEFTS
                     WPGHTEFSVYLPIRK"
     gene            23193..24602
                     /gene="glnG"
                     /locus_tag="RHX21_002375"
     CDS             23193..24602
                     /gene="glnG"
                     /locus_tag="RHX21_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulation protein NR(I)"
                     /protein_id="HDV1987545.1"
                     /translation="MQRGIVWVVDDDSSIRWVLERALAGAGLTCTTFENGAEVLEALA
                     SKTPDVLLSDIRMPGMDGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYL
                     PKPFDIDEAVALVERAISHYQEQQQPRNIQLNGPTTDIIGEAPAMQDVFRIIGRLSRS
                     SISVLINGESGTGKELVAHALHRHSPRAKAPFIALNMAAIPKDLIESELFGHEKGAFT
                     GANTIRQGRFEQADGGTLFLDEIGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRI
                     IAATHQNLEQRVQEGKFREDLFHRLNVIRVHLPPLRERREDIPRLARHFLQVAARELG
                     VEAKLLHPETEAALTRLAWPGNVRQLENTCRWLTVMAAGQEVLIQDLPGELFESTVAE
                     STSQMQPDSWATLLAQWADRALRSGHQNLLSEAQPELERTLLTTALRHTQGHKQEAAR
                     LLGWGRNTLTRKLKELGME"
     gene            24714..24824
                     /locus_tag="RHX21_002376"
     CDS             24714..24824
                     /locus_tag="RHX21_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YshB family small membrane protein"
                     /protein_id="HDV1987546.1"
                     /translation="MLESIINLVSSGAVDSHTPQTAVAAVLCAAMIGLFS"
     gene            complement(25053..26426)
                     /gene="hemN"
                     /locus_tag="RHX21_002377"
     CDS             complement(25053..26426)
                     /gene="hemN"
                     /locus_tag="RHX21_002377"
                     /EC_number="1.3.98.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312816.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HDV1987547.1"
                     /translation="MSVQQIDWDLALIQKYNYSGPRYTSYPTALEFSEDFGEQAFLQA
                     VARYPERPLSLYVHIPFCHKLCYFCGCNKIVTRQQHKADQYLDALEQEIVHRAPLFAG
                     RHVSQLHWGGGTPTYLNKAQISRLMKLLRENFQFNADAEISIEVDPREIELDVLDHLR
                     AEGFNRLSMGVQDFNKEVQRLVNREQDEEFIFALLNHAREIGFTSTNIDLIYGLPKQT
                     PESFAFTLKRVAELNPDRLSVFNYAHLPTIFAAQRKIKDADLPSPQQKLDILQETIAF
                     LTQSGYQFIGMDHFARPDDELAVAQREGVLHRNFQGYTTQGDTDLLGMGVSAISMIGD
                     CYAQNQKELKQYYQQVDEQGNALWRGIALTRDDCIRRDVIKSLICNFRLDYAPIEKQW
                     DLHFADYFAEDLKLLAPLAKDGLVDVDEKGIQVTAKGRLLIRNICMCFDTYLRQKARM
                     QQFSRVI"
     gene            complement(26615..27124)
                     /gene="yihI"
                     /locus_tag="RHX21_002378"
     CDS             complement(26615..27124)
                     /gene="yihI"
                     /locus_tag="RHX21_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Der GTPase-activating protein YihI"
                     /protein_id="HDV1987548.1"
                     /translation="MKPSSSNSRSKGHAKARRKTREELDQEARDRKRQKKRRGHAPGS
                     RAAGGNTTSGSKGQNAPKDPRIGSKTPIPLGVTEKVTKQHKPKSEKPMLSPQAELELL
                     ETDERLDALLERLEAGETLSAEEQSWVDAKLDRIDELMQKLGLSYDDDEEEEEDEKQE
                     DMMRLLRGN"
     gene            27706..28338
                     /locus_tag="RHX21_002379"
     CDS             27706..28338
                     /locus_tag="RHX21_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418301.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HDV1987549.1"
                     /translation="MTNLNYQQTHFVMSAPDIRHLPSDTGIEVAFAGRSNAGKSSALN
                     TLTNQKSLARTSKTPGRTQLINLFEVADGKRLVDLPGYGYAEVPEEMKRKWQRALGEY
                     LEKRQSLQGLVVLMDIRHPLKDLDQQMIEWAVDSNIAVLVLLTKADKLASGARKAQLN
                     MVREAVLAFNGDVQVETFSSLKKQGVDKLRQKLDTWFSEMQPVEETQDGE"
     gene            complement(28719..31505)
                     /gene="polA"
                     /locus_tag="RHX21_002380"
     CDS             complement(28719..31505)
                     /gene="polA"
                     /locus_tag="RHX21_002380"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HDV1987550.1"
                     /translation="MVQIPQNPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLN
                     MLRSLIMQYKPTHAAVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHAMVKAM
                     GLPLLAVSGVEADDVIGTLAREAEKAGRPVLISTGDKDMAQLVTPNITLINTMTNTIL
                     GPEEVVNKYGVPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEP
                     EKIAGLSFRGAKTMAAKLEQNKEVAYLSYQLATIKTDVELELTCEQLEVQQPAAEELL
                     GLFKKYEFKRWTADVEAGKWLQAKGAKPAAKPQETSVADEAPEVTATVISYDNYVTIL
                     DEETLKAWIAKLEKAPVFAFDTETDSLDNISANLVGLSFAIEPGVAAYIPVAHDYLDA
                     PDQISRERALELLKPLLEDEKALKVGQNLKYDRGILANYGIELRGIAFDTMLESYILN
                     SVAGRHDMDSLAERWLKHKTITFEEIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQL
                     HLKMWPDLQKHKGPLNVFENIEMPLVPVLSRIERNGVKIDPKVLHNHSEELTLRLAEL
                     EKKAHEIAGEEFNLSSTKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLP
                     KVILEYRGLAKLKSTYTDKLPLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVR
                     NEEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHLSRDKGLLTAFAEGKDIHRATAAE
                     VFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLARQLNIPRKEAQKYMDLYFERYPGV
                     LEYMERTRAQAKEQGYVETLDGRRLYLPDIKSSNGARRAAAERAAINAPMQGTAADII
                     KRAMIAVDAWLQAEQPRVRMIMQVHDELVFEVHKDDVDAVAKQIHQLMENCTRLDVPL
                     LVEVGSGENWDQAH"
BASE COUNT         7685 a         8200 c         7854 g         7932 t
ORIGIN      
        1 gctcctgaac agtgatgtag caagacacgt atggagccaa cgaagaataa aaatttatag
       61 agttcttatt taatataacc gaaatagcca aggactaata taaatgacct gaatgagaga
      121 ggcagcaccg cccctctcca tcagctactc ttcttcgttc ccgccctctt catacgggcc
      181 aaatggcttc gcgggcagaa cgatatacgt gccttcaaac actgcacccg gcgtctcgtc
      241 gccaaagatt tcgacctgca tctgcacccg tgcttttcgt ccgcgcgcca gacggtcgag
      301 atcgccgctt aaggcaccga ggtcggctac cgcatgaggt ttaccgctaa tcggcttgct
      361 gtagcggata tgcgcatccg caagaataat cgttccgccg aggtggcgtt cacgcagcat
      421 cagccagata agtccccaac cggtgagcgt cgccagtgag aataaactcc cggcaaacag
      481 cgtatggtgc ggattctgat tgccggtttc tggcatggta gtgataaatt tttgcccggt
      541 atattgctga atgcgcacgc ccattttttc actaagcggg atatgttcgt accacgcctg
      601 ttgcagctgc gcgcaccagt cgccgcgatg cagaatgtca tccagagtgg cgacgggctt
      661 aatcatcaaa aaatggcgaa tcggcgtggt ggttggcgtg gtgatttctc cctgattaac
      721 aaaccccagc ttggcgaaaa actccaccgc gtcttcacgg gcgctacagg tcacgcgctt
      781 aacgccttcc tgacgcgcca ccgactccag ggtcatcgcc atcagcgtgc ctaacccttt
      841 gtcctgcacg tcgggatgaa cggccataaa gcgaatggac gcttcattgt cggcattaat
      901 atacagtcgg cctaccgcca ccagattacc ctgctcgtcg acgaccatct ggtgatgcgc
      961 catcgcatcc cacgcgtcgc gttccgaacc ttttggttga tgcaggggct tacgcaacat
     1021 ttcccagcga aactgatagt aacgctctaa ttcttcttct gtttgtggaa cccgaaggtg
     1081 atacatagcg atactctctc ttgtttcccg tgacaaccct ggaagctggc tcatacctgc
     1141 aaccagaatg tcacggggcc atcattgacc agcgatacct gcatatccgc agcgaagcgt
     1201 cctgtttgcg tgttcatctc ttgctgacgg cagcgttcga cgaaatagtc atataacgcc
     1261 tctgcgcgat ccggtgatgc acctttggag aaacttgggc gcatcccccg ttcggtatct
     1321 gcggcgaggg taaactggga aaccaccagc acactgccgc ccgcctgttg cacgttgaga
     1381 ttcatcttgc cttcggcatc gctaaagatg cggtagccga gcacacgctc gcacagacgg
     1441 tttgctttct gttcgtcgtc atccttttcg acacccaata acaccaaaag tcccgcgcca
     1501 atttcgcccg tcacttctcc ctccacggtg acgctggcac gggttacgcg ttgaattaat
     1561 gcaatcatgg ttcgtcgtct tcttcttgtt cagctgcttg ttttagtttg cggtattccc
     1621 cgagagtgac agtaatttcc gcgccaagca agacgataca ccatgtccag tagacccaaa
     1681 caaagagaat ggggatcacc gccagcacac cgtaaatgag ctgatatgac gggaacatgg
     1741 tgatataaag cgcgaaacct ttctttcctg cttcgaacag gagtgcggcg acaaacgcgc
     1801 cgacaatcgc gtcgcggtta ggtacgcgga tggtaggaac aatgctgtac agcaaccaga
     1861 aggagatcca cgacaacagc aacggaaaaa tacgcagcac gttgtcgatg acagtattga
     1921 gatcgctcgc ccagcgcagg gagagcaaat aggaactgat cgccagactg gcccctgcca
     1981 gcagcggccc cagcgttaaa atcatccagt acacggcgaa cgagtaaatt tttggtcgcg
     2041 ctcgtttact gcgccagatg gtattcaacg cgctatcgat ggagtacatc aacaataacg
     2101 cggtgacgat cagcccgcac gccccaacgg cggtcatctt gttggaattg gcaacaaatt
     2161 gttcgatata ccgctgaata acatcgccag tagcaggcag aaagttggca aaaataaagt
     2221 gacgtaactg aatgctgacg tcggaaaaca tgggaaaagc ggcgaaaagc gcaaaaacaa
     2281 cggcaaccag cggcactaat gagagcaacg acacataggc aaggttacct gccagggttg
     2341 tcatgttgtc ctcatcaatg cgttgccaga gtagttttag ccaggcccat agtggacggg
     2401 tacggtgcct ggctttgtcc tgaatggttt ttagcataac accttcgcga aatagtccgg
     2461 gatggtggtt ttatctttca ccagaatact ggtaatgccc agctgattgg ctccttctat
     2521 attatcggcg ttatcgtcga aaaagaccgt atcgctgggt gaaaaacctt ccgcctgcaa
     2581 aacatgctgg taaattcgtg cttcaggttt gcgcatcccc agatcttgcg acagatagat
     2641 atggtcagca gcatcacgaa tttccgggta ttcttccggc cagaaggtgg tatgcaggcg
     2701 gttggtattg gaaagcacca ccacgcgatg cccctgctca cgcagtttat gcatgatggc
     2761 gatcacttcc gggcgcagcg caacaaacac cgcctgccag ccgtgagaga actgctcgta
     2821 gcttagcggt agagccatct catgacacag cgcctctgcg aacgcttcgt cgctaatttc
     2881 cccacgctca tgctgatgaa acgcctcccc catatgaaaa ctcttcttaa gcgatgccag
     2941 cggaatacgc gttaaatcgc tccaggctcc cagcacacgg ttaaagtcga tatcgacaat
     3001 cacattacct aaatcaaaga tatagagcat ttttgcctcc tttcgcgcca caagaaatta
     3061 actgtagcgg gaaaggatgg gtttggctat gtggcaaggt atgaagccag gtcaacagtc
     3121 acaaaaatct acgcgtcttc ctggggaagg atgatttcaa tttggctgtc ttgtaagcgt
     3181 gattttagcg cagcgggcgg cagctcgtcg gtaaagagcg cagtgacctg tgccacgtta
     3241 ccaatttcaa ccgccgccga agcatgatac ttagtgtgat cggcgaccag cagaatattt
     3301 ctcgcgtgcg ccatcatcgt tttcaccacg ttagcttcgt ttacatcaaa ctccatcaac
     3361 gcgccatcgc tctcaatcgc cccaacgctt gttaccagat aatcagcacg aaaatcagcc
     3421 acaaaggacg ccgctgaagg gccaatgatc ccgctattat gagagcgcaa cgtaccgccg
     3481 ggcaccatca cttcaaagcg cgggttgtgg taaagaatat gcgccacacg caggctgttg
     3541 gtgattatcc gcaaatgatt atggttaagt aacgcccggg caacatgctc aacagtcgta
     3601 ccaatggtga taaatattgt tgaaccatca ggaatatagt ctgccaccgc ttcggcaatc
     3661 gctttttttt cctcggtttg cgaaacctca cgctgctcga acgccgtatt aacgacgctg
     3721 gaagcccgac ccgcgccacc gtgatggcgc gtaatcaggc cttgctcgct taatttacga
     3781 atatcccggc ggaccgtctg cgtggagaca tccagcagat ttgccagctc atcaatattc
     3841 atatacccac gctcggcgat cagcatgagg agttggtcgt gccgcgggtt accggttagt
     3901 tcggtaaggc tcatgaaaat tcctcgaaaa accatcaccc tggcatttta tacaaaaagt
     3961 gacaaaaaag atcgggtttg atcacagtca gggatcccgg ctcgtccacc gggacgtgtg
     4021 cattttaacg ccgctacacc gctggcgaag cggactgact ccgctaaatc cccacttgtt
     4081 gccagcgcca ccgccaaagc gccgtgaaaa acatcacccg cacctgtggt atctaccaca
     4141 tcaactttga aggccggttg atgctgacgc ccaccatttt ccagccagtc gcagcctgcg
     4201 ctaccctggg tcacatagac atgaccattt gtgagcgttt gtgcctgttt tagcgcactg
     4261 gccatctctt tcacgcccgt taagcgcgcc agacccggtt ctgaaaaggc cgcgtgatcg
     4321 cttaatgcca ccagctcact gatatcctgc ggcgtaatgt ccccgtccag aacggtcatc
     4381 acacccgcct gacgggccag ggtgaaggct tttttagcgc cgtcgtgcca gcgtacatct
     4441 gccagcacaa catcccactg agagaaatca atttcctcca accactctgc gtcaggcagc
     4501 agatccgggc tggggtagtt aatgattatc cgctcgcctt tggtatccac catgatggcg
     4561 gattgcgaag atttcgcctg gttataccgt ttggtgtaac gggtgttaac gccccaggat
     4621 tccagctctg ccagcaggct gttgcccgtg tcgtcatcac ctacgcgacc aataaaatcg
     4681 acctgcgccc ccagccttgc cgccgcaacc gctgccgtcg ccgctggccc gccaccaact
     4741 tccgtataat ttctcgccac gtatttaccg ctctccgtcg gtaacccttc cacgtaatag
     4801 atgcgatcca tcacggttat acctacacaa gcaacacgaa tcatggttat tccttaaaca
     4861 ttttgggatg cgttcatttt aatttcacca attgtttaaa aagtgacggc tgtcaatttt
     4921 ttgacgataa attacaaata cgatcaaaaa cagacaagca aagcatgtca taaatgacaa
     4981 aaagtgacat cactgtattc aggagagggt tatggcagca atcgcgttta tcggtttagg
     5041 acaaatgggt tcgccaatgg cgagcaattt attgcagcaa gggcaccaac ttcgcgtctt
     5101 tgatgtgaat gccgaggctg tgcggcatct ggtagacaaa ggcgcgactc ccgccgccaa
     5161 cccggcgcag gccgctaaag atgccgaatt tatcattacc atgttgccga atggcgatct
     5221 ggtgcgcagc gtgttgttcg gtgagaacgg cgtttgcgaa agcttatcta ccgatgcgct
     5281 ggtcattgat atgtcgacca tccatccgct gcaaaccgat aaattgattg ccgatatgca
     5341 agccaaaggc ttcagcatga tggatgttcc ggtaggccgt acttctgcaa atgccattac
     5401 cggtactctg ttactgctgg ctggaggcac cgctgaacaa gttgaacgtg ccacgccgat
     5461 cctgatggcg atgggcagtg agttgatcaa cgctggcggt ccgggcatgg ggatccgcgt
     5521 taagctcatc aacaactata tgagcatcgc gctcaatgcg ctttcggcag aagctgccgt
     5581 tttgtgcgaa gccctgaatc ttcccttcga tgttgccgtc aaagtgatga gcggtaccgc
     5641 cgccggtaaa ggccacttca ccacttcctg gccaaacaaa gtcctcagcg gagatctttc
     5701 tcccgccttc atgatcgatc ttgcccataa ggatcttggc atcgcccttg atgtcgccaa
     5761 ccagctgcat gtgccaatgc cgctgggggc cgcctcacgg gaggtttata gccaggcgcg
     5821 cgcagcgggt cgcggtcgcc aggactggtc cgccattctg gaacaggtcc gtgtcagtgc
     5881 cgggatgact gccaaagtaa aaatgtaacg actggataaa ggaataaatg aatgaataag
     5941 tacaccatca acgacattac gcgcgcatcg ggcggttttg ccatgctggc ggtcgatcag
     6001 cgcgaagcca tgcgcatgat gtttgccgcg gctggggcac ccgctccggt agccgatagc
     6061 gttttaactg atttcaaagt taacgctgca aaggccctct cgccttatgc ctcggcgatt
     6121 ctggtagatc aacaattctg ctaccgccag gtggttgagc aaaacgcgat tgccaaaagt
     6181 tgcgccatga ttgtcgccgc cgatgaattc attcctggca acggtattcc ggtcgatagc
     6241 gtggttattg accgcaaaat caacccgcta caaatcaaac aagacggtgg caaagcctta
     6301 aaactgctgg tgctgtggcg tagtgatgaa gatgcgcagc aacgtctgga tatggtgaaa
     6361 gagttcaacg aactgtgcca ctcacacggt ctggtaagca ttattgagcc agtcgtccgc
     6421 ccaccgcgtc gtggcgataa attcgatcgc gaacaagcga tcatcgatgc cgccaaagag
     6481 ctgggcgaca gtggcgctga cctctacaaa gttgaaatgc cgctttatgg caaaggtccg
     6541 caacaagagc ttctctgtgc ttcacaacgt ctgaatgacc atatcaatat gccatgggtg
     6601 atcctctctt ccggtgtcga cgaaaaactg ttcccgcgtg ccgtacgcgt ggcaatgacg
     6661 gcgggcgcat cgggattcct ggcaggccgt gcagtctggg catcggtcgt cggtttacca
     6721 gacaacgagc tgatgctgcg tgacgtttgc gcaccgaaat tacaacaact tggcgatatc
     6781 gtcgacgaaa tgatggctaa acgccgctaa aatgaggata aaaggaatga aatggtttaa
     6841 caccctaagc cacaaccgtt ggctggaaca ggaaaccgac cgcatctttg attttggtaa
     6901 aaattccgta gtgccgactg gttttggctg gttaggcaat aaagggcaaa tcaaagaaga
     6961 gatgggcacc catctgtgga tcaccgctcg tatgttgcac gtttattccg ttgctgcggc
     7021 gatgggtcga cctggcgctt actcgttggt tgatcacggt atcaaagcca tgaacggcgc
     7081 actgcgtgat aaaaaatatg gcggctggta tgcctgcgtg aatgacgagg gcgtggtgga
     7141 tgcctccaaa cagggctatc aacacttctt tgctctgctg ggtgccgcca gcgccgtcac
     7201 aacgggtcac ccggaagcgc gcaagctgct cgattacacc attgaaatta tcgagaaata
     7261 tttctggagc gaagaagagc agatgtgcct ggaatcctgg gacgaagcct tcagcaaaac
     7321 cgaagagtac cgcggcggca atgccaatat gcacgcggtg gaagctttct tgattgttta
     7381 tgacgtcact cacgacaaaa aatggctgga tcgcgcgatt cgcgtggctt ccgtgattat
     7441 ccacgacgtc gccagaaata atcattatcg cgttaacgaa cacttcgata cccagtggaa
     7501 tccgctgccg gattacaaca aagataaccc ggcgcatcgc ttccgcgcgt tcggaggtac
     7561 accaggccac tggatcgaat ggggccgttt aatgctgcac atccatgctg ccctggaagc
     7621 ccgttgcgaa caaccaccag catggctgct agaagatgcc aaaggtctgt ttaacgccac
     7681 cgtgcgcgat gcctgggcac ccgatggcgc ggacgggatt gtttataccg ttgactggga
     7741 aggaaaaccg gtggtccgcg aacgtgtacg ttggcctatc gtcgaagcaa tggatacggc
     7801 ctacgcgctc tacaccgtca ctggcgatcg ccagtatgaa acctggtatc aaacatggtg
     7861 ggagtactgc attaagtacc tgatggacta tgaaaatggt tcctggtggc aggagctgga
     7921 tgcggacaat aaggtcacca ccaaagtctg ggacggcaaa caggatattt atcacctgct
     7981 gcattgcctg gtgatcccgc gtatcccgtt agcgcccggc atggctccag cggttgcagc
     8041 gggtctgctg gatattaatg cgaaataact gatctgaaaa tagggtgcgg gttttcccct
     8101 ctccctaacc ctctccccaa aggggcgagg ggaccgtccg gtgcagtttt tgggtttgac
     8161 atcagcctca cgggaggctg tatgtcgtta attaaggtgc cttgtatgca aatcaccaat
     8221 atgcattgca gtggacagac cgtttcactt gccgcggggg attatcacgc gaccattgtg
     8281 accgtcggtg ctggtctggc tgaattaacc tttcagggtt gtcatttagt catcccgcac
     8341 aaacccgaag agatgccgct ggcgcatctg ggtaaagtgc ttattccgtg gccgaaccgg
     8401 atcgccaacg gctgttaccg ctatcagggg caggaatatc agttacccat taatgaacat
     8461 agttcaaaag ccgctattca cgggctgctt gcctggcgag actggcaaat tagtgaatta
     8521 accgccacca gcgttaccct gacagctttt ctgccgccca gttacggcta tccgtttatg
     8581 ctggcttcac aagttgttta ttcgctcaac gcacacacgg gtctttccgt tgagatcgca
     8641 agccagaata tcggcactgt cgcagcgcct tatggcgtgg gtattcatcc ttatttaacc
     8701 tgcaacttaa catctgttga tgaatatctg ttccagcttc cggcaaacca ggtttatgcc
     8761 gtcgatgagc acgcgaatcc gacaacgctt caccacgttg atgagctgga tttaaatttc
     8821 acgcaggcga aaaaaatagc cgcgacaaaa atcgaccaca cctttaaaac cgctaatgat
     8881 ttgtgggaaa tgaccattac ccatccacag caggcgcttt cggtaagcct ttgttccgat
     8941 caactctggg tgcaggttta tagcggtgaa aaattacagc gtcagggact ggcagttgaa
     9001 cctatgagtt gcccgcctaa cgcctttaat tcaggtatcg acttattatt actggaatca
     9061 ggaaaaccgc accgcctgtt ttttaatatt tacggacaga gaaaataact tgtattgatt
     9121 agcagtcaaa atcattgaag aacatttcac tcgctaaagg caacattatg tatcttcaat
     9181 ttattaagtt aaaaacagct cagcttctgt aaagttttta tatatcagtt ttatgagaat
     9241 cattttatat aagcctgtaa taacaggaag gcaacaatct cgttctcaac tctatggaga
     9301 ttagttatgg atacgccacg tccacagtta ttagattttc aatttcatca gaataacgac
     9361 agttttaccc tacattttca acaacgtctt attttaaccc atagcaaaga taatccttgt
     9421 ttatggattg gctcaggtat agcggatatc gatatgttcc gcggtaattt cagcattaaa
     9481 gataaactac aggagaaaat tgcgcttacc gacgccatcg tcagccagtc accggatggt
     9541 tggttaattc atttcagccg tggttctgac attagcgcca cgctgaatat ctctgccgac
     9601 gatcagggcc gtttattgct ggaactacaa aacgacaacc ttaaccacaa ccgcatctgg
     9661 ctgcgccttg ccgcacagcc ggaagatcat atctacggct gcggtgaaca gttttcctac
     9721 tttgatctgc gcggcaaacc gttcccactg tggaccagtg aacaaggcgt tggtcgcaac
     9781 aaacaaacct atgtcacctg gcaggccgac tgcaaagaaa atgcgggcgg cgactattac
     9841 tggactttct tcccgcagcc tacgtttgtc agcacgcaga agtattactg ccatgttgat
     9901 aacagttgct acatgaactt cgactttagt gccccggaat accatgaact ggcgctgtgg
     9961 gaagacaaag caacgctgcg ttttgaatgt gctgacacat acatctccct gttagaaaaa
    10021 ttaaccgccc tgctgggacg ccagccagaa ctgcccgact ggatttatga cggggtgacg
    10081 ctcggtattc agggcggcac tgaggtgtgc cagaagaaac tggacaccat gcgtaacgcg
    10141 ggcgtgaagg tcaacggcat ctgggcgcag gactggtccg gtattcgtat gacctctttt
    10201 ggcaaacgcg taatgtggaa ctggaagtgg aacagcgaaa actacccgca actggactca
    10261 tgcattaagc agtggaacca ggagggcgtg cagttcctgg cctatatcaa cccgtatgtt
    10321 gccagcgata aagacctctg cgaagaagcg gcaaagcgcg gctatctggc aaaagatgcc
    10381 gccggtggcg attatctggt ggaatttggc gagttctacg gcggcgttgt cgatctcact
    10441 aatcctgaag cctacgcttg gttcaaggaa gtgatcaaaa agaacatgat tgaactcggc
    10501 tgcggcggct ggatggctga cttcggcgag tatctgccca ccgacactta cctgcataac
    10561 ggcgtcagcg ccgaaattat gcataacgcc tggcccgcgc tgtgggcgaa gtgtaactac
    10621 gaagcccttg aagaaacggg caagctcggc gagatccttt tctttatgcg cgccggttct
    10681 accggtagcc agaaatactc caccatgatg tgggcgggcg accagaacgt cgactggagt
    10741 ctcgacgatg gcctggcgtc ggttgtcccg gcggcgctgt cgctggcaat gaccggacat
    10801 ggcctgcatc acagcgacat tggcggttac accaccctgt ttgagatgaa gcgcagcaaa
    10861 gagctgttgc tgcgctggtg cgatttcagc gccttcacgc cgatgatgcg cacccacgaa
    10921 ggtaaccgtc ctggcgacaa ctggcagttt gacggcgacg cagaaactat cgcccatttt
    10981 gcccgtatga cctccgtctt caccaccctg aaaccttacc tgaaagaggc tgtcgcgctg
    11041 aatgcgaagt ccggcctgcc ggttatgcgc ccgctgttcc tgcattacga agacgatgcg
    11101 cacacttaca ccctgaaata tcagtacctg ttaggtcgcg acattctggt cgctccggtg
    11161 catgaagaag gccgtagcga ctggacgctc tatctgccgg aggataactg ggtccacgcc
    11221 tggacgggtg aagcgttccg gggcggggaa gttaccgtta atacgcccat cggcaagccg
    11281 ccggtctttt atcgcgccga tagcgaatgg gcggcactgt tcgcgtcgtt aaaaagcatc
    11341 taatcacatc cgcccgtggg gaaactcatg ggcaaaggga gaacatcgat gagtcacatc
    11401 acaacggaag atccagcaac tttacgcctg ccctttaaag agaaactctc ttacggtatt
    11461 ggcgacctgg cctctaacat cctgctagat atcggtacgc tttatctttt gaagttttat
    11521 accgacgttc tggggctgcc aggcacctat ggcggcatta tctttttgat ttcaaaattc
    11581 tttactgcgt ttaccgatat gggtaccggc attatgttgg attcccgacg caagatcggt
    11641 ccaaaaggta agttccgtcc ttttattctg tatgcgtcat tcccggtcac cttactggcg
    11701 atcgccaact ttgtcggcac accgtttgat gtcaccggta aaacggtgat ggccactatt
    11761 ctgtttatgc tttacggact gtttttcagc atgatgaact gctcctacgg cgcaatggtc
    11821 ccggcaatca ccaaaaaccc caacgaacgc gcctcactgg cggcatggcg tcagggcggc
    11881 gctacgctgg gcctgctgct gtgcacggtg ggattcgtgc cagttatgaa tcttatcgaa
    11941 ggtaatcaga aacttggcta tatcttcgcc gccacgctgt tttcactgtt cggcctgctg
    12001 tttatgtgga tctgctactc aggcgtgaaa gagcgttatg tcgaaaccca accaaccaat
    12061 ccggcgcaaa agcctggcct gttgcaatct ttccgcgcaa ttgccggtaa ccgcccactg
    12121 ttcattctgt gtattgccaa cctctgcacc ttaggggcgt ttaacgtcaa gctcgccatt
    12181 caggtctatt acacccagta cgtacttaac gatcccatcc tgttgtcgta tatgggattt
    12241 ttcagcatgg gctgtatttt catcggcgtg ttcctgatgc ctggcgcagt cagacgtttt
    12301 ggtaagaaga aggtctatat cggcggcctg ctgatttggg tgctgggcga tctgctcaac
    12361 tatttcttcg gcggcggctc ggtcagcttt gtggcgttct cctgcctggc gttcttcggc
    12421 tcagcgtttg ttaacagcct gaactgggcg ctggtttccg acaccgtcga gtacggcgag
    12481 tggcgcaccg gcgtgcgttc ggaaggcacg gtctacaccg gcttcacctt ctttcgcaaa
    12541 gtgtctcagg cgctggctgg tttcttcccc ggctggatgc tgacgcaaat tggctatgtg
    12601 ccgaacgtcg cacaggctga ccacaccatt gaagggttac gccagttgat cttcatctac
    12661 ccaagcgcac tggcggtagt caccattgtg gcgatgggtt gcttctacag cctgaacgag
    12721 aagatgtatg tccgcattgt ggaagagata gaagcccgta aacgcacggc gtaataataa
    12781 taaacgacgc cctgcggggc gttataagga gtgattatgt ctgaccataa tccactgaca
    12841 ttaaaactga atctgcggga aaaaatcgcc tatggtatgg gcgacgtcgg ttcgaattta
    12901 atgctctgca tcggtactct gtatctcctc aaattttata ccgatgaatt agggatgcct
    12961 gcttactatg gcgggattat ctttctggtg gcgaagtttt ttaccgcgtt taccgatatg
    13021 ctcaccggat ttttactcga ctcgcggaaa aatattgggc ctaaaggcaa atttcgtccc
    13081 tttattttat atgcagcggt tccggcggcg ttaattgcaa cgctccagtt tatcgccacc
    13141 accttttgtt tgccggttaa aacgacgatt gccaccgcgc tgtttatgat gtttggactt
    13201 tcatacagtc tgatgaactg ctcgtatggt gcgatgatcc cggcaattac caaaaacccg
    13261 aatgagcgcg cgcagctcgc ggcttaccgc cagggtggtg caaccatagg gctattgatt
    13321 tgtaccgtgg cgtttattcc gttgcagtcg cttttttctg actcaaccgt cggttatgcc
    13381 tgtgcggcac ttatgttctc cattggcggc tttattttta tgatgctgtg ctacagaggc
    13441 gtcaaagagc attatgtgga cacaacgcca accggacata aagccagtat tctcaaatca
    13501 ttttgcgcga tatttcggaa tccgccattg ctggttttat gcattgctaa cttgtgtacc
    13561 ctggcggcat ttaatatcaa actggcgatt caggtctatt acacccagta tgtgctgaat
    13621 gatattaatt tattgtcgtg gatgggattc ttcagtatgg gatgcatcct catcggcgta
    13681 ttactggtgc cattaactgt aaaatgtttt ggtaaaaaac aggtttatct ggctggcatg
    13741 gtgctgtggg cggtgggtga tatactgaat tatttctggg gaagtaactc tttcactttc
    13801 gtcatgttct cttgtgtcgc cttttttggc acggcctttg taaacagcct gaactgggca
    13861 ctggtaccag ataccgtaga ttacggtgaa tggaaaaccg gtattcgtgc cgaaggttct
    13921 gtttataccg gttatacctt ctttcgtaaa atttctgccg cacttgctgg cttcttgcca
    13981 ggcattatgc tgacgcaaat tggttatgtt cccaacatcg cgcaaagcga tgcgacatta
    14041 cagggtttgc gtcagctcat ttttatctgg ccttgtgcac tggcaattat tgctgcattg
    14101 acgatgggat tcttttacac actcaatgaa aaacggtttg cattgattat tgaggaaatc
    14161 aaccaacgca aaaataaaga gatggcgaca gaagaaaaaa cggcttccgt aacgttataa
    14221 atgtcaatag ccgctatttc catcctggtg ggtggcggcc tccctacgtt taaaaaatgg
    14281 acttattatg aaaaagatta atgcaataat tttattatct tctctgacct ctgcctcggt
    14341 atttgctggc gcatacgtcg aaaacaggga ggcatataat cttgcctccg atcagggcga
    14401 ggttatgcta cgtgtgggtt ataacttcga tatgggtgcg ggtattatgt taaccaatac
    14461 ctacaacttt cagcgagaag atgaactaaa acatggatat aacgaaattg aaggctggta
    14521 tccgttattt aaaccaaccg ataaattaac catccagccc ggtggcttaa ttaatgataa
    14581 gagtatcggt tcgggtggtg cagtgtatct ggacgtcaac tataaatttg taccatggtt
    14641 taatctgaca gtacgaaatc gctataacca taataactat agttcaacag atttgagcgg
    14701 ggaactggat aataatgaca cctatgaaat tggcacctac tggaatttta aaatcaccga
    14761 taaattttcc tatacatttg agccacatta cttcatgcga gtgaatgact ttaatagtag
    14821 caacgggaaa gatcatcatt gggaaatcac taacaccttc cgttaccgta ttaatgaaca
    14881 ctggctccct tatttcgaat tgcgctggtt agaccgcaac gtcgaaccgt accaccgcga
    14941 gcaaaaccag atccgtatcg ggacgaagta tttcttctga tgtgaaactg ccggatgcgg
    15001 cgtaaacgcc ttatccggcc tacggttgat acggttttca ttggccggat taagcacatc
    15061 cggccattaa ttaagcttca gccgccagca tctctttctt acgttggcta atacgcttaa
    15121 ccagcattac ggaaaccacc gcaccactga atgcgaagca ggccataatg ccaaacacga
    15181 ttttgtagcc aataatcccc ggatttaaat ccagaatgta gccatacaga ctgaagcaga
    15241 acatcgccgg agcgtaacca ataaagctac ccaacgccat cgccgcacct gttttatttt
    15301 cagcaatttt tgcttcgccg ataggtgcaa aaaatacggc tcgctgtgta aagactatcg
    15361 cgccaaagcc cagcgtacat gccatcccta aatagaccgg catactttcg tgcggcagca
    15421 taatcaacag tacgagcgca gcggtactaa tgataaaggt gtagcataga tatttacttg
    15481 gcgatttcag gatcttatct gaaatcatgc caccaatcgg tccaccaatc attttcagac
    15541 agtattggtt aatgatgccg taagccccca ccagcgcaac gggcaataga tagatgtttt
    15601 tcaggaatgg aatgaagaat gtcaggccac agtaaaccgc gtaaacgaag aagacgttaa
    15661 aagcgataag ccagatagtt ttgtctttca gcaccgaggt catactggtg tttttcgatg
    15721 ctccgtcttc ttttttcacc tcaacggacg gtgcctcttc tttgtcattc agaacaaaga
    15781 aaatgataat gcctacggca atcacaataa gggaatagaa ccagatgcct gctttaaaac
    15841 ccaataagcc actgccaaac caggtaaata ctgccaacgc agaaaatgcc accacggtat
    15901 cgacaatgcc acgccctgtt tcgaagaagc caaacaaccg accttgttgt tcgctattgc
    15961 ccaatcgact taccgacttg agcaagaccg gccagttcat catgtcgcaa gtaacgccaa
    16021 atagcgccca gacaaagagg atgccccaat accccggcat tgtcgtcaaa taaacaccca
    16081 gtaatcctgt cgcaatgagt gagaatgaca tggtgtatct gcgcggtagt ttatcggcaa
    16141 aataaataga cagaaaaaaa cccactgtcg tgacaaatga gtttaccgac atagcattac
    16201 caatttgacc attggtcaaa tggaaatatt cctgcatcgg gatataaaac gcatctttca
    16261 gcgacggtaa tttataaatt gtaccgccac acaatgttaa tagactaaat aacgcccatt
    16321 tctttttcgt gagcataaca tcccctaagc gatttttaaa atcactgttt tataggcaat
    16381 aagataccga ccattcatat ggaatggttt tattaactgc gtatgagtta aaacttatta
    16441 gtggttcaga agatggtttg cctcttgttt gatttgttgt agtacgttac gcacatgatt
    16501 tatctgatta attgcatctt ctttttcttt acgtaaccgc gcatccagta aatgattttc
    16561 tggcaatggt gtttcactca tctggcgata agggatccac ggattatcat cttcgtcttc
    16621 aaagcggaac gccggcgcat agtaatcaac ctcttcttcc aggccatatg ccgtcacctg
    16681 cggctcatca tcacccaggc agataaggtg cgttaataac gctttgaacg gcatatcacc
    16741 ctgacctgaa atacaggctt tatgacccag gccaccctgt tctttaacga tcaaggcatc
    16801 tttgatatgg acctgggtaa tatgcggtgc catcgttttt aaggcgtcga tgggatgctc
    16861 atttgcattg atcatgttcg caaaatcaaa cagtaaggaa agagactcca tctcactttc
    16921 tttgaccagc gacaccagct catgactttt taaatcttca tgctgctcga tcgtaaaagt
    16981 caggccgctg tcctgatacg tttcccgtac ataggcaatg tcgttagcga taatcgataa
    17041 tacgtcgcgc aaattacctt cataacgtgg ataaaaacgt acggacgatg ccccagtttt
    17101 caacgcgatg gcgacggctt cgtcaataga tgccttatat gaggcgctgg tttcaatatg
    17161 aatatcaagg ttcagacggc gggctttatc tccaaaggca gagagttctt tatcgtccat
    17221 attaccaaga gaaaaacgct cgccatccag aacatggatt ttgacgccac gtagattatt
    17281 ttcacttgcg atatcaagta aatcagcagg caacactctt tccagccgca tatttaaatg
    17341 aaaggcataa gcatgtaaat aaagaggaag agtgtcgaca cgttgtagaa tctttcttgc
    17401 gttatttatt gtcaccataa aacacctaca gattaatgat gaggtctacg gcctcaaatc
    17461 gccaatattc aatatctatc tggacaatat tgccttgctg gtcggcgcga tgcttttcaa
    17521 ttaagatcgc tggcataccc gcagaaccgc caagatactt gctgatatca cccggcattc
    17581 tgacgggttt gaaaatcaat ttttttacta ccgtctcttt ttggtagcac ttttcccaga
    17641 ctgcagaaaa tgagtggttt tcaagttgtt caataaaacc cggagcaact tcaggattaa
    17701 tatatgtttc gtgatagaaa actttatgtc cttccagcgc cccccagccg gtgatgcgat
    17761 agagttcagt tgatggtgtc actgcaatca gtggcgcgag cgtctcggga atatcgctgg
    17821 tacggttttt ctcggtaaac ccccaggaag gctctcgtcc ttgctcaatt gcggcccgct
    17881 gaaagctcgc tgacagctcc ggactgtaat taaatcgcgg ctgggtcacg aaccacccct
    17941 tacgatcctt acggaagatt ttggattctg cctcgaggtt caacaacgcc tggcgcagcg
    18001 tcatacgttt aatgcccagc agttctccca gctctctttc tgaagggagt tttccacccg
    18061 gcgtggtgat gccatctttc aaccaccgat ccagtttctc ttttgcattt tctacggtgg
    18121 attgattctc cgccattgtt taatcctttt ggtttaaacc agatgaagca tcttacgctt
    18181 acgccaaaaa agaaagcaat taacggcgta tgactttgca gataattgtg acaaagctct
    18241 ctattgacgt aatcccagac ttataaggga gatactcgca ttggtgtgcg ctcacgacag
    18301 gtaaaaaaaa acctgccagc gatggcaggt tttttataac taaaaaacga aattaatcgt
    18361 ctttcggtgc gcggttggcg cgacgacgat cgttttcagt caggtgacgt ttacgaatac
    18421 ggatagaggt cggagtcact tctaccagtt cgtcatcatc gatgaactcc agagcttgtt
    18481 ccagagtcat gcggataggc ggaaccagaa caacggcttc gtcagtaccg gaagcacgca
    18541 tgttggtcag tttcttacca gtcaggcagt ttaccgtcag gtcgttagag cggctgtgaa
    18601 taccgataat ctgaccttcg taaacttctg caccgtgacc gaggaacagc ttaccgcgat
    18661 cctgcagacc gaacagcgcg aacgcgaccg ctttaccctg accgttagag atcagtacgc
    18721 cgttctgacg ctgacccact tcacccggac gtacgtcgtc gtagtggctg aaggtggagt
    18781 acagcagacc agtaccggaa gtcatggtca tgaactcaga acggaagcca atcagaccac
    18841 ggcttgggat cacgtagtcg agacgtacgc ggcctttacc gtctggattc atgtttttca
    18901 ggtcgccttt acgttcgccc agcgcctgca ttacagaacc ctgatgctgt tcttcaacgt
    18961 ccagagtcac gttttcatac ggctcttgtt tacgaccgtc gatttcacgg aagataactt
    19021 tcggacggga taccgccagt tcgaaacctt cacgacgcat gttttcgatc agaacagaca
    19081 ggtgcagttc gccacgacca gaaacgcgga acgcatcggc gtcttcggtt tcttctacgc
    19141 gcagcgcaac gttgtgtacc agttctttgt tcagacgatc caggatctga cgagacgtta
    19201 cgaacttacc ttctttaccg cagaacggcg aggtgttaac gcagaagaac atagaaacgg
    19261 tcggctcatc aacggagagt gccggcagcg cttcaacgtt ttgcgtgtcg caaacggtgt
    19321 cagaaatgtt cagttcgcca aggcccgtga tcgcaacgat atcgccagct tccgccagat
    19381 cggtttcgat acgttccaga ccgaggtggc ccagcacttt accgactttc gcgttgcggg
    19441 ttttgccttc gctatcgatg atagtgacct gctggttcgg cttcacttta ccgcgcttga
    19501 tgcggccaat gccgataacg ccaacatagc tgttgtaatc gagctgagaa atctgcatct
    19561 ggaacggacc gtcaaggtca acgtccggcg caggaacgtg atcaacaatc gcctgataca
    19621 gcggggtcat gtcttccgcc atatcttcgt ggtccagacc cgcgataccg ttcagcgcag
    19681 aagcgtaaac gatcgggaag tccagctgct cgtcggtcgc gtcgaggtta acgaacagat
    19741 cgaatacctg atccacaacc caatcaggac gcgcgccagg gcggtcaact ttgttgataa
    19801 caacaatcgg cttcaggccg taagcaaacg cttttttggt tacgaagcgc gtttgcggca
    19861 tcgggccgtc aaatgcgtca accaccagca gcactgagtc taccatggac attacacgtt
    19921 caacttcacc accgaagtcg gcgtgccccg gggtatcaac gatgttgata cggtaatcat
    19981 tccatttgat agcggtgttt ttcgcgagga tggtaatccc acgctctttc tccaaatcgt
    20041 tggagtccat cacgcgctct tgggtttcgg cacgagagtc gaacgtaccg gattgttgga
    20101 gcagcttgtc taccagggtg gttttaccat ggtctacgtg cgcgatgatg gcgatattac
    20161 gcaatttttc gatcacaact ttgcctcagg cattagaaat agcgcgttat tgtacacgga
    20221 ttaatcgcac tacaaaacag gatcacaaac atcctccgca aacaagtatt gcagagtccc
    20281 tttgtgatcg ctttcacgga gcataaaaag ggttatccaa aggtcattgc accaacatgg
    20341 tgcttaatgt ttccattgaa gcactatatt ggtgcaacat tcacatcgtg gtgcagccct
    20401 tttgcacgat ggtgcgcatg ataacgcctt ttaggggcaa tttaaaagtt ggcacagatt
    20461 tcgctttatc ttttttacgg cgacacggcc aaaataattg cagatttcgt taccacgacg
    20521 accatgacca atccaggaga gttaaagtat gtccgctgaa cacgtactga cgatgctgaa
    20581 cgagcacgaa gtgaagtttg ttgatttgcg cttcaccgat actaaaggta aagaacagca
    20641 cgtcactatc cctgctcatc aggtgaatgc tgaattcttc gaagaaggca aaatgtttga
    20701 cggctcctcg attggcggct ggaaaggcat taacgagtcc gacatggtgc tgatgccaga
    20761 cgcatccacc gcagtgattg acccgttctt cgccgactcc accctgatta tccgttgcga
    20821 catccttgaa cctggcaccc tgcaaggcta tgaccgtgac ccgcgctcca ttgcgaagcg
    20881 cgccgaagat tacctgcgtt ccactggcat tgccgacacc gtactgttcg ggccagaacc
    20941 tgaattcttc ctgttcgatg acatccgttt cggatcatct atctccggtt ctcacgttgc
    21001 tatcgacgat atcgaaggcg catggaactc ctccacccaa tatgaaggtg gtaacaaagg
    21061 tcaccgtccg gcagtgaaag gcggttactt cccggttccg ccggtagact ctgctcagga
    21121 tattcgttct gaaatgtgtc tggtgatgga acagatgggc ctggtggttg aagcccatca
    21181 ccacgaagta gcgactgctg gtcagaacga agtggctacc cgcttcaata ccatgaccaa
    21241 aaaagctgac gaaattcaga tctacaaata tgttgtgcac aacgtagcgc accgcttcgg
    21301 taaaaccgcg acctttatgc caaaaccgat gttcggtgat aacggctccg gtatgcactg
    21361 ccacatgtct ctgtctaaaa acggcgttaa cctgttcgca ggcgacaaat acgcaggtct
    21421 gtctgagcag gcgctgtact acattggcgg cgtaatcaaa cacgctaaag cgattaacgc
    21481 cctggcaaac ccgaccacca actcttataa gcgtctggtc ccgggctatg aagcaccggt
    21541 aatgctggct tactctgcgc gtaaccgttc tgcgtctatc cgtattccgg tggtttcttc
    21601 tccgaaagca cgtcgtatcg aagtacgttt cccggatccg gcagctaacc cgtacctgtg
    21661 ctttgctgcc ctgctgatgg ccggtcttga tggtatcaag aacaagatcc atccgggcga
    21721 agccatggac aaaaacctgt atgacctgcc gccagaagaa gcgaaagaga tcccacaggt
    21781 tgcaggctct ctggaagaag cactgaacga actggatctg gaccgcgagt tcctgaaagc
    21841 cggtggcgtg ttcactgacg aagcaattga tgcgtacatc gctctgcgtc gcgaagaaga
    21901 tgaccgcgtg cgtatgactc cgcatccggt agagtttgag ctgtactaca gcgtctaata
    21961 gttgaagttg tactacccgg cgcaacaacg ccgggattta gttgccgtgg aaactttcag
    22021 cccatctctg catgggcttt tttctccgtc aattctctga tgcttcgcgc tttttatccg
    22081 taaaaagcta taatgcacta aaatggtgca acctgttcag gagactgctt tatggcaaca
    22141 ggcacgcagc ccgatgctgg gcagatcctc aactcgctga ttaacagtat tttgttaatc
    22201 gatgacaacc tggcgatcca ttacgccaac cccgccgcgc aacaactgct cgcccaaagc
    22261 tcccgcaaat tgtttggtac accgttaccg gaactgttga gctacttctc attaaatatc
    22321 gagctgatgc aagaaagtct ggaggcgggg caaggtttta ccgataacga agtgacgctg
    22381 gtcatcgacg ggcgctcgca tatcctttct gtgacggccc agcgtatgcc ggacggcatg
    22441 atcctgctgg agatggctcc gatggataac cagcgccgct taagtcagga acagctacag
    22501 cacgcccagc aggttgctgc ccgtgattta gtgcgcggcc tggcacatga gattaaaaat
    22561 ccgcttggcg gtttacgtgg cgcggcgcag ctgctcagca aagcgttacc tgacccatca
    22621 ctactcgaat ataccaaagt gattatcgaa caggcggacc ggctgcgaaa tctggtcgac
    22681 cgtctgttgg ggccgcagct gcccggtacg cgcgttaccg aaagtattca caaagtggct
    22741 gaacgcgtgg taacgctggt gtcgatggaa ctgccggaca acgtgcggtt gattcgtgat
    22801 tacgatccca gcctgccgga actggcgcac gacccggatc aaattgaaca ggtcttgctg
    22861 aatattgtgc gcaatgcgct acaggcgctg gggccggaag gcggtgaaat cattctgcgt
    22921 acccgcaccg cgtttcaact gaccttacac ggcgagcgct accggctggc ggcgcggatt
    22981 gatgtggaag ataacgggcc gggcattccg cctcatttgc aggatacgct gttttacccg
    23041 atggtcagcg gccgcgaagg tggcaccggg cttggcttat ccatcgctcg taatttgatt
    23101 gatcagcatt caggcaaaat tgaatttacc agttggccag ggcataccga gttctcggtt
    23161 tacctgccta tcaggaaata aaggtgacgt ttatgcaacg agggatagtc tgggtagtcg
    23221 atgacgatag ttccatccgt tgggtgcttg aacgtgcgct cgctggagcg ggtttaacct
    23281 gtacgacatt tgagaacggc gcggaagtac tggaggcgct ggcgagcaaa acgccggatg
    23341 tgctgctttc agatattcgt atgccgggaa tggacgggct ggcgctgctc aagcagatta
    23401 aacagcgcca tccaatgctt ccggtcatca ttatgaccgc acattccgat ctggatgctg
    23461 ccgtcagcgc ctatcaacaa ggggcgtttg attatctgcc caaaccgttt gatatcgacg
    23521 aagcagtggc gctggttgag cgcgctatca gtcattacca ggaacagcag cagccgcgta
    23581 atattcagct taacggccca acgaccgata tcatcggcga agcgccagcc atgcaggacg
    23641 tgttccgtat tatcggtcgg ctttcgcgtt cttctattag cgtgctgatt aacggcgaat
    23701 ccggcaccgg taaagaactg gtcgctcatg ccctgcatcg ccacagtccg cgcgccaaag
    23761 cgccgtttat cgcgctgaat atggcagcta tcccaaaaga tttgatcgaa tcagaactgt
    23821 ttggccacga gaaaggcgcg tttactggcg cgaataccat tcgtcagggg cgttttgaac
    23881 aggccgatgg cggtacatta ttcctcgacg aaattggtga tatgccgctg gatgtgcaga
    23941 cgcgtttgct gcgcgtgctg gcagacggtc agttttaccg cgttggcggc tatgcgccgg
    24001 tgaaagtgga tgtgcggatt atcgctgcca ctcaccagaa tctcgaacag cgagtgcagg
    24061 aaggtaagtt ccgtgaggat ctgttccacc gcctgaacgt tatccgcgtt catctgccgc
    24121 cgctgcgcga acgtcgggaa gatattcccc gtctggcgcg ccatttttta caggttgccg
    24181 cgcgcgaact gggcgtagaa gcgaagttgc tgcatccgga aaccgaagct gctctgacgc
    24241 gtctggcgtg gccaggcaac gtacgccagc tggaaaacac ctgccgctgg ctaacggtga
    24301 tggccgccgg gcaggaagtg ttgattcagg atttgcccgg cgaactgttt gaatcaacgg
    24361 ttgcggagag tacttcgcaa atgcaaccgg acagttgggc gacactttta gcgcagtggg
    24421 cagacagagc gctgcgttcc ggtcatcaaa atctgctttc cgaagcgcag ccagagctgg
    24481 agcggacgtt actgacgacc gcgttgcgac atacgcaggg gcataaacag gaagcggcgc
    24541 ggctactcgg ctggggccgc aacaccctga cgcgtaagtt aaaagagctg gggatggagt
    24601 gattcacagc ttgtgtgtaa agattgatta ttgagcgcaa attgctggta ttttgcgctt
    24661 tactgttccg ataagttcag tatgatcttg cccggaaaac ggggagagtc attatgctgg
    24721 aatcaataat taatctggta tcgagtggcg cagttgacag ccacacaccg caaactgccg
    24781 ttgctgccgt gctgtgtgcc gcgatgattg ggctgtttag ctgaagctcg ttgtttatgc
    24841 cggatgcgga gaaagtcgta ggcctgataa gacgcgacca gcgccgcatc aggcatcatg
    24901 ctcagatgcc tgatgcggcg taaacgcctt atccggccta caaaagcaat aatttcaaca
    24961 ggttttgttg cccagcgcat caggcaatct tgttctcagc acattgatgg cgctttcgtt
    25021 ttctactttg taaacgaagc gccattcact atttaaatca cccgagagaa ctgctgcatc
    25081 cgcgctttct ggcgcagata ggtatcaaag cacatgcaaa tgttgcggat cagcaagcga
    25141 cctttcgccg tcacctgtat tcccttctca tccacatcca ccagcccatc ttttgctaac
    25201 ggggcgagca gcttgagatc ttccgcaaag taatcagcga agtgcaaatc ccactgtttc
    25261 tcaatagggg cgtaatccag acggaagttg cagatgagcg acttaatcac atcgcggcga
    25321 atacagtcat cacgcgttag cgcaatacca cgccacagcg cattgccttg ttcatccact
    25381 tgctgatagt actgcttcaa ctctttctgg ttctgcgcgt agcagtcgcc aatcatgctg
    25441 atggcggaaa cgcccatccc cagcagatcg gtatcgccct gagtggtgta gccctggaag
    25501 ttacgatgca gcacgccttc acgctgggcc accgccagct cgtcatccgg acgggcaaag
    25561 tgatccatac cgataaactg atagcccgat tgcgtcagga aggcgatggt ttcctgcagg
    25621 atatcgagtt tttgctgcgg actcggcagg tcagcatctt tgattttgcg ctgagcagca
    25681 aaaatggtcg gcagatgcgc gtagttaaag acactcagac gatcggggtt cagctccgcc
    25741 acacgtttca gggtaaaggc gaaactctcc ggcgtctgtt tcggcaggcc gtaaatcagg
    25801 tcgatgttgg tggaggtaaa accaatctca cgcgcatggt taagcagtgc aaagatgaac
    25861 tcttcatcct gctcgcggtt aaccagacgt tgcacttctt tgttgaagtc ctgcacgccc
    25921 atgctcaggc gattaaagcc ttcggcgcgt aaatgatcga gtacatccag ttcgatttcc
    25981 cgcggatcga cttcgatcga aatctccgca tcggcattga actggaagtt ttcgcgcagc
    26041 agcttcatca ggcggctgat ttgcgcttta ttcagatacg tcggcgttcc gccgccccag
    26101 tgcaattggc tgacgtgacg cccggcgaac agcggtgcac gatggacgat ttcttgctcc
    26161 agcgcgtcca gatactgatc ggccttgtgc tgctggcgag taacaatctt attgcaaccg
    26221 cagaagtaac aaagcttatg gcagaacggg atatgtacgt agagagataa tggacgctca
    26281 ggatagcgcg ccacggcttg taaaaacgcc tgttcgccga agtcttctga aaactccagc
    26341 gcggtcgggt acgaggtgta tcgtggcccg gaatagttat atttctggat cagggccaga
    26401 tcccagtcga tttgctgtac agacatgctc actccttccg atggcgtctc tggcggctac
    26461 ggcgtaccgg cggatgcccg tttcgggtca tcagccggtt gcgcagccac ttttgtcgcc
    26521 gcgacaaccg ctgtagttta acgaataacc acaccagata acatataacc ggaagggtta
    26581 tcagcagaac gggaaggccc acggcggcaa tccgttagtt gccccgcagc agacgcatca
    26641 tgtcttcttg cttctcgtct tcttcctctt cttcgtcatc gtcataagag aggccgagtt
    26701 tctgcatcaa ctcatcaata cgatccagtt tagcatccac ccaggattgc tcttcggcac
    26761 tcagggtttc gcctgcttcc agacgttcca gcagcgcatc cagacgctca tccgtttcca
    26821 gtaattccaa ctccgcctgc ggtgaaagca taggtttctc actcttcggt ttgtgctgtt
    26881 tggtgacttt ttcagtcacg cccaatggaa taggggtttt actgccaata cgtggatctt
    26941 ttggtgcgtt ctggcctttg ctgcctgacg tggtgtttcc gcccgctgcg cggctgcccg
    27001 gcgcatgacc acgacgtttt ttctgacgct tgcgatcacg agcttcctga tccagctcct
    27061 cgcgtgtttt tcgacgcgct tttgcatgac ctttgctgcg tgagtttgaa gatgatggtt
    27121 tcataatggt tcgtctttta gccgttttat tcagtataga tttgcggcgg aatctaacag
    27181 aaagcaagca aagaaaaaag gcgacagatt actctgtcgc cttttttcct gactcataac
    27241 ccttaacggg tcttacaatc cttgcaggcc gccaacacac cctgtttttc ctttagccgg
    27301 aacaatccgt gttgattcca tttccgttta attacgtctc cggacgtttg tcttcctgac
    27361 aatcctctgt cttcgcctcc tggcgctcct gaccctcatc ctgagtcatt gttcctgtta
    27421 gcgtcctcgc tctatgggtg ctactttacg cctttgcttt aaacaaacaa tcaaccgcca
    27481 tcagtatttg cacattttca gagttttata taaaagcaat tcactgattt atatagctta
    27541 tttgacatgc atcgcagaat tttctctgct atttcgcata aagactatcg gcaatgtctc
    27601 acaaagcgta tggcttttac ttacaacgct cacgccgaaa aatccgcctt ttattatggt
    27661 tcaggtataa tcgccacaaa gctttgactg acggagacga ccgctttgac taatttgaat
    27721 tatcaacaga cgcattttgt gatgagtgcg cctgatattc gccacctacc ttccgatacc
    27781 ggaattgaag tggcttttgc aggccgttcc aacgcaggta aatccagcgc gctgaacacg
    27841 ctgactaacc agaaaagcct ggctcgtacc tcaaaaaccc cagggcgcac ccagcttatc
    27901 aacctgtttg aagtggctga cggcaagcgt ctggttgact tgcctgggta cggttatgcg
    27961 gaagtcccgg aagagatgaa gcgcaaatgg cagcgtgcgc tcggcgaata cctcgaaaaa
    28021 cgtcagagcc tgcaaggtct ggtggtgcta atggatattc gccatccgct gaaagatttg
    28081 gatcagcaga tgattgagtg ggcggtagac agcaatatcg ccgttctggt gctgctgacc
    28141 aaagcggaca aactggcaag cggcgcacgt aaagcgcaat tgaatatggt gcgtgaagct
    28201 gtactggcgt ttaacggtga tgtgcaggtt gaaacgtttt cttcgttgaa gaaacaaggc
    28261 gtggacaagc tgcggcagaa actggatacc tggtttagcg agatgcagcc tgtagaagaa
    28321 acgcaggacg gcgaataatt ttcttgcctt aatgcttgtg ccggatgtgg cgtatccggc
    28381 ccgtaaattc aatagattac aattctaccg ttggcctgat aaacatagcg catcaggcat
    28441 tacggatctt ttctttcgcc caataaaaaa cgccccagtc attactgact ggggcggcta
    28501 aaatattcag ccaaatccga ttacgtgaag taaaaggtct gaaagataga acatcttacc
    28561 tctgtaccct acgcgactaa ctttactctt ttttgttcag ttcagaaagc actttttgta
    28621 attttttttc agttgttgca taggaatttc taatagccat cacaaaacgt gacagcttat
    28681 gttgcttact tacgaaaaaa ggcatgttca ggcgaatctt agtgcgcctg atcccagttt
    28741 tcgccactcc ccacttccac cagcaacggc acatccagac gggtacagtt ttccatcagt
    28801 tgatgaatct gcttcgcgac ggcatcaaca tcatctttat gaacttcaaa taccagttca
    28861 tcgtgtacct gcatgatcat acgtacacgc ggttgctcag cctgtaacca cgcatcaacg
    28921 gcaatcatcg cccgtttgat aatgtcggcg gcggttccct gcattggcgc gttaatggct
    28981 gcacgttcag ccgctgcacg acgagcacca ttgctggatt tgatatccgg cagatacaga
    29041 cggcgtccgt ccagcgtttc aacgtagccc tgctctttcg cctgagcacg ggtgcgttcc
    29101 atatactcca gcacgccagg gtagcgttcg aagtaaaggt ccatgtactt ctgcgcttct
    29161 ttacgtggaa tgttcaattg ccgcgccaga ccgaaagcac tcatgccata aatcagacca
    29221 aagttgatcg ctttcgcgct acggcgttgc tcgctggtga cggtttccag tggcaaacca
    29281 aacacttctg ccgccgttgc ccggtggata tcttttcctt ccgcgaatgc ggtcagcaag
    29341 cctttgtcac gcgaaagatg cgccataatg cgcagttcaa tctgcgagta gtccgctgag
    29401 acaatcacat aatcctctgg cgcaataaac gcctggcgga tacgacgacc ttcttcgtta
    29461 cgcaccggaa tgttttgcag gttaggatcg gttgacgata aacgtcccgt tgcagttact
    29521 gcctggtgat aagaggtatg cacacgcccg gttttcgggt tgatcatcag cggcagcttg
    29581 tcggtgtagg tcgatttcag cttcgccaga ccacgatact ccagaatcac ttttggcaac
    29641 ggatagtcca gcgccagttc ttccagtacc tcttccgacg ttgacggcgc gccacccggc
    29701 gttttcttca gcggtttaat gccctgtttt tcaaagagaa tggtttgtaa ctgcttggtg
    29761 gaagaaaggt taaattcctc acctgcaatt tcatgcgctt tcttttccag ctcagccaga
    29821 cgaagggtga gctcttcaga atgattgtgc agcactttcg gatcgatctt cacaccgtta
    29881 cgttcaatgc gtgaaagcac cggcaccagc ggcatttcga tattctcgaa gacgttcaac
    29941 ggccctttgt gtttttgcag atccggccac attttcagat gcaactgcaa ggtgacatct
    30001 gcatcttcgg cggcgtaacg tccggcttct tcgagggcaa tctggttaaa ggtcagttga
    30061 tttttgcctt taccagcaat ctcttcaaaa gtgatggttt tgtgcttcaa ccaacgttcc
    30121 gcgaggctgt ccatatcgtg acgcccggca acgctattga gaatgtagga ctccagcatg
    30181 gtatcaaacg caatcccacg cagttcaatg ccgtagttcg ccagaatacc gcgatcgtat
    30241 ttcaggtttt gcccgacctt cagcgccttt tcatcttcca gcagcggttt tagcaactcg
    30301 agtgcacgct cgcgagagat ttgatcgggc gcatcaagat aatcatgagc aaccggaata
    30361 tatgccgcta cgcctggctc gatagcaaaa gaaagcccga ccaggttagc agagatgtta
    30421 tcaaggctgt cggtttcggt atcaaatgca aataccggcg ctttttccag cttcgcaatc
    30481 cacgctttca gtgtttcttc atcaaggatg gtgacgtagt tgtcataaga aatcaccgtt
    30541 gccgtcactt ctggtgcttc gtctgcaaca ctggtttcct gtggcttcgc ggctggtttt
    30601 gcccctttgg cctgtaacca tttgcccgct tcgacatcag cagtccagcg tttgaactca
    30661 tactttttga acagccccaa caactcttcc gctgccggtt gctgcacttc cagttgttca
    30721 caggtcagct ccagttcaac gtcggtttta atcgtcgcca gctggtatga gagataagca
    30781 acttctttgt tttgctcgag cttcgctgcc attgttttcg cgccacggaa gctcaaccca
    30841 gcaatttttt ctggctcggc atacagcgta tccagtccgc caagaccttg cagcaatgcc
    30901 tgcgcggttt tttcaccgac gcccggtacg ccaggaatgt tatcagagga gtcacccatc
    30961 agcgccagga aatcgatgat cagttctggc ggcacgccgt acttattcac cacctcttcc
    31021 ggtccgagga tggtattcgt catggtattg ataagcgtaa tatttggcgt caccagttgc
    31081 gccatatctt tatcgccagt gctgatcagc accggacgcc cggctttttc ggcttcgcgc
    31141 gccagagtac cgataacgtc gtccgcttct acgccagaaa ccgccagcag cggcagtccc
    31201 atcgctttaa ccatcgcgtg caagggttcg atttgtgcac gcagatcgtc cggcattggc
    31261 gggcgatgtg atttgtaatg ttcaaacagt tcatcacgaa aggtttttcc cttggcgtca
    31321 aagaccaccg ctgcatgcgt cggtttatat tgcatgatca gactgcgcag catgttgagg
    31381 acaccataca tcgcaccggt cggctcgcct gcgctgttag tcagcggggg aaacgcgtga
    31441 tatgcgcgat aaagataaga tgaaccatct acaaggataa gtggattttg ggggatctga
    31501 accataatgt ccgtgcctgt ttatcagatt atgggtaaag gatgccacag acaggatgaa
    31561 aacatgagtt tttcaccgct tttcgtgaaa atcttttgta gatcttctgg atcgctcgca
    31621 aatcgtcatg tggataactt tgtgcataaa ttatttacat cgcttttaat t
//
LOCUS       DAPGUL010000049        31057 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.049, whole genome shotgun sequence.
ACCESSION   DAPGUL010000049 DAPGUL010000000
VERSION     DAPGUL010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 31057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31057
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.049"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..231
                     /gene="tuf"
                     /locus_tag="RHX21_002381"
     CDS             <1..231
                     /gene="tuf"
                     /locus_tag="RHX21_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312930.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDV1987551.1"
                     /translation="RHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVT
                     LIHPIAMDDGLRFAIREGGRTVGAGVVAKVLS"
     gene            461..844
                     /gene="secE"
                     /locus_tag="RHX21_002382"
     CDS             461..844
                     /gene="secE"
                     /locus_tag="RHX21_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007665874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HDV1987552.1"
                     /translation="MSANTEAQGSGRGLEAMKWVVVVALLLVAIVGNYLYRDIMLPLR
                     ALAVVILIAAAGGVALLTTKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTA
                     VMSLILWGLDGILVRLVSFITGLRF"
     gene            846..1391
                     /gene="nusG"
                     /locus_tag="RHX21_002383"
     CDS             846..1391
                     /gene="nusG"
                     /locus_tag="RHX21_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005280494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HDV1987553.1"
                     /translation="MSEAPKKRWYVVQAFSGFEGRVATSLREHIKLHNMEDLFGEVMV
                     PTEEVVEIRGGQRRKSERKFFPGYVLVQMVMNDASWHLVRSVPRVMGFIGGTSDRPAP
                     ISDKEVDAIMNRLQQVGDKPRPKTLFEPGEMVRVNDGPFADFNGVVEEVDYEKSRLKV
                     SVSIFGRATPVELDFSQVEKA"
     gene            1550..1978
                     /gene="rplK"
                     /locus_tag="RHX21_002384"
     CDS             1550..1978
                     /gene="rplK"
                     /locus_tag="RHX21_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006121495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HDV1987554.1"
                     /translation="MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNA
                     KTDSIEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKIS
                     RAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED"
     gene            1982..2686
                     /gene="rplA"
                     /locus_tag="RHX21_002385"
     CDS             1982..2686
                     /gene="rplA"
                     /locus_tag="RHX21_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HDV1987555.1"
                     /translation="MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFVESVDV
                     AVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGANAEAAKAAGAELVGMEDLAD
                     QIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQ
                     VRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPTQAKGVYIKKVSISTTM
                     GAGVAVDQAGLSASVN"
     gene            3099..3596
                     /gene="rplJ"
                     /locus_tag="RHX21_002386"
     CDS             3099..3596
                     /gene="rplJ"
                     /locus_tag="RHX21_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002438625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HDV1987556.1"
                     /translation="MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKA
                     GREAGVYMRVVRNTLLRRAVEGTPFECLKDAFVGPTLIAYSMEHPGAAARLFKEFAKA
                     NAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRD
                     AKEAA"
     gene            3663..4028
                     /gene="rplL"
                     /locus_tag="RHX21_002387"
     CDS             3663..4028
                     /gene="rplL"
                     /locus_tag="RHX21_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HDV1987557.1"
                     /translation="MSITKDQIIEAVAAMSVMDVVELISAMEEKFGVSAAAAVAVAAG
                     PVEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKD
                     DAEALKKALEEAGAEVEVK"
     gene            4348..8376
                     /gene="rpoB"
                     /locus_tag="RHX21_002388"
     CDS             4348..8376
                     /gene="rpoB"
                     /locus_tag="RHX21_002388"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004870488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDV1987558.1"
                     /translation="MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPE
                     GQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRL
                     VIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD
                     KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTE
                     QILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQ
                     LEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDLLAKLSQSGHKRIE
                     TLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSE
                     DRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGN
                     RRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGS
                     SQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEG
                     PNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLD
                     EEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMG
                     ANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDE
                     MYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQ
                     NMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPN
                     VGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVK
                     DSSLRVPNGVSGTVIDVQVFTRDGVEKDKRTLEIEEMQLKQAKKDLSEELQILEAGLF
                     SRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLE
                     AKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYD
                     ENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQ
                     RAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDL
                     PTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGK
                     AQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMP
                     ESFNVLLKEIRSLGINIELEDE"
     gene            8453..12676
                     /gene="rpoC"
                     /locus_tag="RHX21_002389"
     CDS             8453..12676
                     /gene="rpoC"
                     /locus_tag="RHX21_002389"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HDV1987559.1"
                     /translation="MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETI
                     NYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERM
                     GHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQIL
                     TEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLT
                     KRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRN
                     NRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGK
                     QGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLAT
                     TIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLH
                     PLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVL
                     GLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAK
                     TSLKDTTVGRAILWMIVPKGLPYSIVNQALGKKAISKMLNTCYRILGLKPTVIFADQI
                     MYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKV
                     IDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQL
                     AGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTR
                     RLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADI
                     LVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHIINKGEA
                     IGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGK
                     LVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITE
                     VSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDV
                     LIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFE
                     ARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERV
                     ERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLR
                     KATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFI
                     SAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAGEA
                     PAAPQVTAEDASASLAELLNAGLGGSDNE"
     gene            12889..13428
                     /locus_tag="RHX21_002390"
     CDS             12889..13428
                     /locus_tag="RHX21_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-shock protein C"
                     /protein_id="HDV1987560.1"
                     /translation="MKQEVEKWRPFGHPDGDIRDLSFLDAHQAVYVQHHEGKEPLEYR
                     FWVTYSLHCFTKDYEHQTNEEKQSLMYHAPKESRPFCQHRYNLARTHLKRTILALPES
                     NVIHAGYGSYAVIEVDLDGGDKAFYFVAFRAFREKKKLRLHVTSAYPISEKQKGKSVK
                     FFTIAYNLLRNKQLPQPSK"
     gene            complement(13838..14971)
                     /gene="thiH"
                     /locus_tag="RHX21_002391"
     CDS             complement(13838..14971)
                     /gene="thiH"
                     /locus_tag="RHX21_002391"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HDV1987561.1"
                     /translation="MKTFSDRWRQLDWDDIRLRINGKTAVDVERALNASQFTRDDMMA
                     LLSPAASGYLEQLAQRAQRLTRQRFGNTVSFYVPLYLSNLCANDCTYCGFSMSNRIKR
                     KTLDEADIARESAAIREMGFEHLLLVTGEHQAKVGMDYFRRHLPALREQFSSLQMEVQ
                     PLAETEYAELKQLGLDGVMVYQETYHEATYARHHLKGKKQDFFWRLETPDRLGRAGID
                     KIGLGALIGLSDNWRVDCYMVAEHLLWLQQHYWQSRYSVSFPRLRPCTGGIEPASIMD
                     ERQLVQTICAFRLLAPEIELSLSTRESPWFRDRVIPLAINNVSAFSKTQPGGYADNHP
                     ELEQFSPHDDRRPEAVAAALIAQGLQPVWKDWDSYLGRASQRL"
     gene            complement(14968..15738)
                     /gene="thiG"
                     /locus_tag="RHX21_002392"
     CDS             complement(14968..15738)
                     /gene="thiG"
                     /locus_tag="RHX21_002392"
                     /EC_number="2.8.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418418.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HDV1987562.1"
                     /translation="MLRIADKTFDSHLFTGTGKFASSQLMVEAIRASGSQLVTLAMKR
                     VDLRQHNDAILEPLIAAGVTLLPNTSGAKTAEEAIFAAHLAREALGTNWLKLEIHPDA
                     RWLLPDPIETLKAAETLVQQGFVVLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQG
                     LETRAMLEIIIQQATVLVVVDAGIGVPSHAAQALEMGADAVLVNTAIAVADDPVNMAK
                     AFRLAVEAGLLARQSGPGSRSHFAHATSPLTGFLEASA"
     gene            complement(15740..15940)
                     /gene="thiS"
                     /locus_tag="RHX21_002393"
     CDS             complement(15740..15940)
                     /gene="thiS"
                     /locus_tag="RHX21_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HDV1987563.1"
                     /translation="MQILFNDQPMQCAAGQTVHELLEQLDQRQAGAALAINQQIVPRE
                     QWAQHIVQDGDQILLFQVIAGG"
     gene            complement(15924..16679)
                     /gene="thiF"
                     /locus_tag="RHX21_002394"
     CDS             complement(15924..16679)
                     /gene="thiF"
                     /locus_tag="RHX21_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418420.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole biosynthesis adenylyltransferase ThiF"
                     /protein_id="HDV1987564.1"
                     /translation="MNDRDFMRYSRQILLDDIALDGQQKLLDSQVLIIGLGGLGTPAA
                     LYLAGAGVGTLVLADDDDVHLSNLQRQILFTTEDIDRPKSQVSQQRLTQLNPDIQLTA
                     LQQRLTGEALKDAVARADVVLDCTDNMATRQEINAACVALNTPLITASAVGFGGQLMV
                     LTPPWEQGCYRCLWPDNQEPERNCRTAGVVGPVVGVMGTLQALEAIKLLSGIETPAGE
                     LRLFDGKSSQWRSLALRRASGCPVCGGSNADPV"
     gene            complement(16672..17307)
                     /gene="thiE"
                     /locus_tag="RHX21_002395"
     CDS             complement(16672..17307)
                     /gene="thiE"
                     /locus_tag="RHX21_002395"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709787.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HDV1987565.1"
                     /translation="MYQPDFPPVPFRLGLYPVVDSVQWIERLLDAGVRTLQLRIKDRR
                     DEEVEADVVAAIALGRRYNARLFINDYWRLAIKHQAYGVHLGQEDLQATDLNAIRAAG
                     LRLGVSTHDDMEIDVALAARPSYIALGHVFPTQTKQMPSAPQGLEQLARHVERLADYP
                     TVAIGGVSLARAPAVIATGVGSIAVVSAITQAADWRLATAQLLEIAGVGDE"
     gene            complement(17307..19202)
                     /gene="thiC"
                     /locus_tag="RHX21_002396"
     CDS             complement(17307..19202)
                     /gene="thiC"
                     /locus_tag="RHX21_002396"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HDV1987566.1"
                     /translation="MSATKLTRREQRAHAQHFIDTLEGTAFPNSKRIYITGTHPGVRV
                     PMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAINVQQGLAKLRQPWID
                     ARGDTEELTVRSSDYTKARLADDGLDELRFSGVLTPKRAKAGRRVTQLHYARQGIITP
                     EMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANI
                     NHPESEPMIIGRNFLVKVNANIGNSAVTSSIEEEVEKLVWSTRWGADTVMDLSTGRYI
                     HETREWILRNSPVPIGTVPIYQALEKVNGIAEDLTWEAFRDTLLEQAEQGVDYFTIHA
                     GVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSL
                     GDGLRPGSIQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEE
                     LEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKE
                     DVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYH
                     DETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAATQTIEMGMADMSENFRARGGEI
                     YLRKEEA"
     regulatory      complement(19282..19382)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(19434..19910)
                     /gene="rsd"
                     /locus_tag="RHX21_002397"
     CDS             complement(19434..19910)
                     /gene="rsd"
                     /locus_tag="RHX21_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma D regulator"
                     /protein_id="HDV1987567.1"
                     /translation="MLNQLDNLTERVRGSNKLVDRWLHVRKHLLVAYYNLVGIKPGKE
                     SYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLARAAKIWPQLEANTQQ
                     IMDYYDSSLETAIDHDNYLEFQQVLSDIGEALEARFVLEDKLILLVLDAARVKHPA"
     gene            20005..20778
                     /gene="nudC"
                     /locus_tag="RHX21_002398"
     CDS             20005..20778
                     /gene="nudC"
                     /locus_tag="RHX21_002398"
                     /EC_number="3.6.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) diphosphatase"
                     /protein_id="HDV1987568.1"
                     /translation="MDRIIEKLDHGWWVVSHEQKLWLPKGELPYGEAANFDLVGQRAL
                     QIGEWQGEPVWLVQQQRRHDMGSVRQVIDLDVGLFQLAGRGVQLAEFYRSHKYCGYCG
                     HEMYPSKTEWAMLCSHCRERYYPQIAPCIIVAIRRDDSILLAQHTRHRNGVHTVLAGF
                     VEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGDIVIDPK
                     ELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYE"
     gene            20818..21882
                     /gene="hemE"
                     /locus_tag="RHX21_002399"
     CDS             20818..21882
                     /gene="hemE"
                     /locus_tag="RHX21_002399"
                     /EC_number="4.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="HDV1987569.1"
                     /translation="MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAG
                     DFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTVPDAMGLGLYFEAGEGPRFTSP
                     VTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGS
                     SKAFTVIKKMMYADPQALHALLDKLAKSVTLYLNAQIKAGAQAVMIFDTWGGVLTGRD
                     YQQFSLYYMHKIVDGLLRENDGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIA
                     DARRRVGNKVALQGNMDPSMLYAPPARIEEEVATILAGFGHGEGHVFNLGHGIHQDVP
                     PEHAGVFVEAVHRLSEQYHR"
     gene            21892..22563
                     /gene="nfi"
                     /locus_tag="RHX21_002400"
     CDS             21892..22563
                     /gene="nfi"
                     /locus_tag="RHX21_002400"
                     /EC_number="3.1.21.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease V"
                     /protein_id="HDV1987570.1"
                     /translation="MDLASLRAQQIELASSVIREDRLDKDPPDLIAGADVGFEQGGEV
                     TRAAMVLLKYPSLELVEYKVARIATTMPYIPGFLSFREYPALLAAWEMLSQKPDLVFV
                     DGHGISHPRRLGVASHFGLMVDVPTIGVAKKRLCGKFEPLSSEPGALAPLMDKGEQLA
                     WVWRSKARCNPLFIATGHRVSVDSALAWVQRCMKGYRLPEPTRWADAVASERPAFVRY
                     TANQP"
     gene            22606..23196
                     /locus_tag="RHX21_002401"
     CDS             22606..23196
                     /locus_tag="RHX21_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjaG family protein"
                     /protein_id="HDV1987571.1"
                     /translation="MLQNPIHLRLERLESWQHVTFMACLCERMYPNYAMFCQQTGFGD
                     GQIYRRILDLIWETLTVKDAKVNFDSQLEKFEEAIPSADDFDLYGVYPAIDACVALSE
                     LVHSRLSGETLEHAVEVSKTSITTVAMLEMTQAGREMSDEELKENPAVEQEWDIQWEI
                     FRLLAECEERDIELIKGLRADLREAGESNIGIIFQQ"
     gene            23383..23655
                     /gene="hupA"
                     /locus_tag="RHX21_002402"
     CDS             23383..23655
                     /gene="hupA"
                     /locus_tag="RHX21_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017460010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein HU-alpha"
                     /protein_id="HDV1987572.1"
                     /translation="MNKTQLIDVIAEKAELSKTQAKAALESTLAAITESLKEGDAVQL
                     VGFGTFKVNHRAERTGRNPQTGKEIKIAAANVPAFVSGKALKDAVK"
     gene            23668..24363
                     /locus_tag="RHX21_002403"
     CDS             23668..24363
                     /locus_tag="RHX21_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1481 domain-containing protein"
                     /protein_id="HDV1987573.1"
                     /translation="MNSFNEGVVSPLLSFWRRSLMLAGALLLTACSHNSSLPPFTASG
                     FAEDQGAVRIWRKDSGDNVHLLAVFSPWRSGDTTTREYRWQGDNLTLININVYSKPPV
                     NIRARFDDRGDLSFMQRESDGEKQQLSNDQIDLYRYRADQIRQISDALRQGRVVLRQG
                     RWHAMEQTVTTCEGQTIKPDLDSQAIAHIERRQSRSSVDVSVAWLEAPEGSQLLLVAN
                     SDFCRWQPNEKTF"
     gene            complement(24365..24790)
                     /gene="zraP"
                     /locus_tag="RHX21_002404"
     CDS             complement(24365..24790)
                     /gene="zraP"
                     /locus_tag="RHX21_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc resistance sensor/chaperone ZraP"
                     /protein_id="HDV1987574.1"
                     /translation="MKRNTKIALVMMALSAMAMGSTSAFAHGGHGMWQQNAAPLTSEQ
                     QTAWQKIHNDFYAQSSALQQQLVTKRYEYNALLAANPPDSSKINAVAKEMENLRQSLD
                     ELRVKRDIAMAEAGIPRGAGMGMGYGGCGGGGHMGMGHW"
     gene            25028..26404
                     /gene="zraS"
                     /locus_tag="RHX21_002405"
     CDS             25028..26404
                     /gene="zraS"
                     /locus_tag="RHX21_002405"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     ZraS"
                     /protein_id="HDV1987575.1"
                     /translation="MRFMQRSKDSLAKWLSAILPVVIVGLVGLFAVTVIRDYGRETAA
                     ARQTLLEKGSVLIRALESGSRVGMGMRMHHAQQQALLEEMAGQPGVRWFAVTDEQGTI
                     VMHSNSGMVGKQLYSPQEMQQLHPGDEEAWRRIDSADGEPVLEIYRQFQPMFAAGMHR
                     MRHMQQYAATPQAIFIAFDASNIVSAEDREQRNTLIILFALATVLLASVLSFFWYRRY
                     LRSRQLLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQL
                     AQVMAKEADRLNRVVSELLELVKPTHLALQAVDLNTLINHSLQLVSQDANSREIQLRF
                     TANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVTVSESGAGVKISVTDSGKG
                     IAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGSTFTLWLPVN
                     ITRKDPQG"
     gene            26401..27726
                     /gene="zraR"
                     /locus_tag="RHX21_002406"
     CDS             26401..27726
                     /gene="zraR"
                     /locus_tag="RHX21_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent response regulator
                     transcription factor ZraR"
                     /protein_id="HDV1987576.1"
                     /translation="MTHDNIDILVVDDDISHCTILQALLRGWGYNVALANSGRQALEQ
                     VREQVFDLVLCDVRMAEMDGIATLKEIKALNPAIPVLIMTAYSSVETAVEALKTGALD
                     YLIKPLDFDNLQATLEKALAHTHSIDAETPAVTASQFGMVGKSSAMQHLLSEIALVAP
                     SEATVLIHGDSGTGKELVARAIHASSARSEKPLVTLNCAALNESLLESELFGHEKGAF
                     TGADKRREGRFVEADGGTLFLDEIGDISPMMQVRLLRAIQEREVQRVGSNQTISVDVR
                     LIAATHRDLAAEVNAGRFRQDLYYRLNVVAIEVPSLRQRREDIPLLAGHFLQRFAERN
                     RKAVKGFTPQAMDLLIHYDWPGNIRELENAVERAVVLLTGEYISERELPLAIAGTPIP
                     LGQSQDIQPLVEVEKEVILAALEKTGGNKTEAARQLGITRKTLLAKLSR"
     gene            complement(27723..29012)
                     /gene="purD"
                     /locus_tag="RHX21_002407"
     CDS             complement(27723..29012)
                     /gene="purD"
                     /locus_tag="RHX21_002407"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HDV1987577.1"
                     /translation="MKVLVIGNGGREHALAWKAAQSPLVETVFVAPGNAGTALEPALQ
                     NVAIGVTDIPALLDFAQNEKIDLTIVGPEAPLVKGVVDTFRAAGLKIFGPTAGAAQLE
                     GSKAFTKDFLARHKIPTAEYQNFTEVEPALAYLREKGAPIVIKADGLAAGKGVIVAMT
                     LEEAEAAVHDMLAGNAFGDAGHRIVIEEFLDGEEASFIVMVDGEHVLPMATSQDHKRV
                     GDKDTGPNTGGMGAYSPAPVVTDEVHQRTMERIIWPTVKGMAAEGNTYTGFLYAGLMI
                     DKQGNPKVIEFNCRFGDPETQPIMLRMKSDLVELCLAACEGKLDEKTSEWDERASLGV
                     VMAAGGYPGDYRTGDVIHGLPLEEVADGKVFHAGTKLADNEQVVTSGGRVLCVTALGH
                     TVAEAQKRAYALMTDIHWDDCFCRKDIGWRAIEREQN"
     gene            complement(29024..30613)
                     /gene="purH"
                     /locus_tag="RHX21_002408"
     CDS             complement(29024..30613)
                     /gene="purH"
                     /locus_tag="RHX21_002408"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HDV1987578.1"
                     /translation="MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLL
                     AEKGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAIMEEHQIQPIDMVV
                     VNLYPFAQTVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEM
                     DDNEGSLTLATRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNL
                     NFIKKQDMRYGENSHQQAAFYIEENVKEASVATATQVQGKALSYNNIADTDAALECVK
                     EFAEPACVIVKHANPCGVAIGNSILDAYDRAYKTDPTSAFGGIIAFNRELDAESAQAI
                     ISRQFVEVIIAPSASEEALKITAAKQNVRVLTCGQWGERVPGLDFKRVNGGLLVQDRD
                     LGMVGAEELRVVTQRQPTEQELRDALFCWKVAKFVKSNAIVYAKNNMTIGIGAGQMSR
                     VYSAKIAGIKAADEGLEVKGSSMASDAFFPFRDGIDAAAAAGVTCVIQPGGSIRDDEV
                     IAAADEHGIAMLFTDMRHFRH"
BASE COUNT         7341 a         8052 c         8483 g         7181 t
ORIGIN      
        1 cgtcatactc cgttcttcaa aggctaccgt ccgcagttct acttccgtac tactgacgtg
       61 actggtacca tcgaactgcc ggaaggcgta gagatggtaa tgccgggcga caacatcaaa
      121 atggttgtta ccctgatcca cccgatcgcg atggacgacg gtctgcgttt cgcaatccgt
      181 gaaggcggcc gtaccgttgg cgcgggcgtt gtagcaaaag ttctgagcta attgccgata
      241 acatttgacg caatgcgcac taaaagggca tcatttgatg ccctttttgc acgctttcgt
      301 accagaacct ggctcatcag tgattttctt tgtcataatc attgctgaga caggctctgt
      361 tgagggcgta taatccgaaa agctaatacg cgtttcgatt tggtttgcct cgcgatcgcg
      421 gggtgaaaat gtttgtagaa aacttctgac aggttggttt atgagtgcga ataccgaagc
      481 tcaaggaagc gggcgcggcc tggaagcgat gaagtgggtc gttgtggtgg cattgctcct
      541 ggtggcgatt gtcggcaact acctttatcg cgacattatg ctgccgctgc gtgcgctggc
      601 cgtagtaatt ctgattgctg cagcgggtgg tgtcgcgctg ttaacgacaa aaggtaaagc
      661 taccgttgct tttgcccgtg aagcgcgtac cgaagtccgt aaggtcattt ggccgactcg
      721 ccaggaaaca ttgcacacca cgctgattgt ggctgcggtt accgcagtaa tgtcactgat
      781 cctgtgggga ctggatggta ttctggttcg cctggtatcc tttatcactg gcctgaggtt
      841 ctgagatgtc tgaagctcct aaaaagcgct ggtacgtcgt tcaggcgttt tccggttttg
      901 aaggccgcgt agcaacgtcg ctacgtgagc atatcaaatt acacaacatg gaagatttgt
      961 ttggtgaagt catggtacca accgaagaag tggttgaaat ccgtggcggt cagcgtcgca
     1021 aaagcgaacg taaattcttc cctggctacg tcctcgttca gatggtgatg aacgacgcga
     1081 gctggcacct ggtgcgcagc gtaccgcgtg tgatgggctt catcggcggt acttccgatc
     1141 gtcctgcgcc aatcagcgat aaagaagtcg atgcgattat gaaccgcctg cagcaggttg
     1201 gtgataagcc gcgtccgaaa acgctgtttg aaccgggtga aatggtccgt gttaatgatg
     1261 gtccgttcgc tgacttcaac ggtgttgttg aagaagtgga ttacgagaaa tctcgtctga
     1321 aagtgtctgt ttctatcttc ggtcgtgcga ccccggtaga gctggacttc agccaggttg
     1381 aaaaagccta acccagcgat caaaaaagcg gcgatttaat cgttgcacaa ggcgcgagat
     1441 tggaatacaa tttcgcgcct tttgttttta tgggccttgc ccgtaaaacg attttttata
     1501 tcacggggag cctctcagag gcgttattac ccaacttgag gaatttataa tggctaagaa
     1561 agtacaagcc tatgtcaagc tgcaggttgc agctggtatg gctaacccga gtccgccagt
     1621 aggtccggct ctgggtcagc agggcgtaaa catcatggaa ttctgcaaag cgttcaacgc
     1681 aaaaactgat tccatcgaaa aaggtctgcc gattccggta gtaatcaccg tttacgctga
     1741 ccgttctttc actttcgtta ccaagactcc gccggcagca gttctgctga aaaaagcggc
     1801 tggtatcaag tctggttccg gtaagccgaa caaagacaaa gtgggtaaaa tttcccgcgc
     1861 tcagctgcag gaaatcgcgc agaccaaagc tgccgacatg actggtgccg acattgaagc
     1921 gatgactcgc tccatcgaag gtactgcacg ttccatgggc ctggtagtgg aggactaaga
     1981 aatggctaaa ctgaccaagc gcatgcgtgt tatccgcgag aaagttgatg caaccaaaca
     2041 gtacgacatc aacgaagcta tcgcactgct gaaagagctg gcgactgcta aattcgtaga
     2101 aagcgtggac gtagctgtta acctcggcat cgacgctcgt aaatctgacc agaacgtacg
     2161 tggtgcaact gtactgccgc acggtactgg ccgttccgtt cgcgtagccg tatttaccca
     2221 gggtgcaaac gctgaagctg ctaaagctgc aggtgctgaa ctggtaggta tggaagatct
     2281 ggctgaccag atcaagaaag gcgaaatgaa ctttgacgtt gttattgctt ctccggatgc
     2341 aatgcgcgtt gttggccagc tgggccaggt tctgggtccg cgcggcctga tgccaaaccc
     2401 gaaagtgggt actgtaacac cgaacgttgc tgaagcggtt aaaaacgcta aagctggcca
     2461 ggttcgttac cgtaacgaca aaaacggcat catccacacc accatcggta aagtggactt
     2521 tgacgctgac aaactgaaag aaaacctgga agctctgctg gttgcgctga aaaaagcaaa
     2581 accgactcag gcgaaaggcg tgtacatcaa gaaagttagc atctccacca ccatgggtgc
     2641 aggtgttgca gttgaccagg ctggcctgag cgcttctgta aactaatgcc tttacgtggg
     2701 cggtgatttt gtctacaatc ttacccccac gtataatgct taatgcagac gtatatccga
     2761 gatattcggg ttgtggcaag gcggcaactg agtgagtcgc caggagcata gctaactatg
     2821 tgactggtgc gaacgaagga agccaacgcc gtcacaagct gaatagcgac ggatagaaaa
     2881 gatttgttcg ttggagcctg gcctatccag gcctccgtcg aagaccgcag gagtttcgca
     2941 agaaacttaa tcccctgcgt agacggtgac agaacgctaa gattattctt ttatattctg
     3001 gcttgtttct gctcaccgta attaagacgc tctctccgtt tggaggagtg aagtgagttc
     3061 cagagatttt ctctggcaaa catccaggag caaagctaat ggctttaaat cttcaagaca
     3121 aacaagcgat tgttgctgaa gtcagcgaag tagccaaagg cgcgctgtct gcagtagttg
     3181 cggattcccg tggcgtaact gtagataaaa tgaccgaact gcgtaaagca ggtcgcgaag
     3241 ctggcgtata catgcgtgtt gttcgtaaca ccctgctgcg ccgtgctgtt gaaggtactc
     3301 cgttcgagtg cctgaaagac gcgtttgttg gtccgaccct gattgcatac tctatggaac
     3361 acccgggcgc tgctgctcgt ctgttcaaag agttcgcgaa agcgaatgca aaatttgagg
     3421 tcaaagccgc tgcctttgaa ggtgagctga tcccggcgtc tcagatcgac cgcctggcaa
     3481 ctctgccgac ctacgaagaa gcaattgcac gcctgatggc aaccatgaaa gaagcttcgg
     3541 ctggcaaact ggttcgtact ctggctgctg tacgcgatgc gaaagaagct gcttaatcgc
     3601 agttatcttt ttaacgcatt cgcttacgta taaacttatt ctgatattca ggaacaattt
     3661 aaatgtctat cactaaagat caaatcattg aagcagttgc agctatgtct gtaatggacg
     3721 ttgtagaact gatctctgca atggaagaaa aattcggtgt ttccgctgct gctgctgtag
     3781 ctgtagctgc tggcccggtt gaagctgctg aagaaaaaac tgaattcgac gtaattctga
     3841 aagctgctgg cgctaacaaa gttgctgtta tcaaagcagt acgtggcgca actggcctgg
     3901 gtctgaaaga agctaaagac ctggtagaat ctgcaccggc tgctctgaaa gaaggcgtga
     3961 gcaaagacga cgcagaagca ctgaaaaaag ctctggaaga agctggcgct gaagttgaag
     4021 ttaaataagc caacccttcc ggttgcagcc tgagaaatca ggctgatggc tggtgacttt
     4081 ttagtcacca gcctttttgc gctgtaaggc gccagtagcg tttcacactg tttgactact
     4141 gctgtgcctt tcaatgcttg tttctatcga cgacttaata tactgcgaca ggacgtccgt
     4201 tctgtgtaaa tcgcaatgaa atggtttaag cgtgatagca acaggcattg cggaaagtgt
     4261 tccattttcc ggtcaacaaa atagtgttgc acaaactgtc cgctcaatgg acagatgggt
     4321 cgacttgtca gcgagctgag gaaccctatg gtttactcct ataccgagaa aaaacgtatt
     4381 cgtaaggatt ttggtaaacg tccacaagtt ctggatgtac cttatctcct ttctatccag
     4441 cttgactcgt ttcagaaatt tatcgagcaa gatcctgaag ggcagtatgg tctggaagct
     4501 gctttccgtt ccgtattccc gattcagagc tacagcggta attccgagct gcaatacgtc
     4561 agctaccgcc ttggcgaacc ggtgtttgac gtccaggaat gtcaaatccg tggcgtgacc
     4621 tattccgcac cgctgcgcgt taaactgcgt ctggtgatct atgagcgcga agcgccggaa
     4681 ggcaccgtaa aagacattaa agaacaagaa gtctacatgg gcgaaattcc gctcatgaca
     4741 gacaacggta cctttgttat caacggtact gagcgtgtta tcgtttccca gctgcaccgt
     4801 agtccgggcg tcttctttga ctccgacaaa ggtaaaaccc actcttcggg taaagtgctg
     4861 tataacgcgc gcatcatccc ttaccgtggt tcctggctgg acttcgaatt cgatccgaag
     4921 gacaacctgt tcgtacgtat cgaccgtcgc cgtaaactgc ctgcgaccat cattctgcgc
     4981 gccctgaact acaccacaga gcagatcctc gacctgttct ttgaaaaagt tatctttgaa
     5041 atccgtgata acaagctgca gatggaactg gtgccggaac gcctgcgtgg tgaaaccgca
     5101 tcttttgaca tcgaagctaa cggtaaagtg tacgtagaaa aaggccgccg tatcactgcg
     5161 cgccacattc gccagctgga aaaagacgac gtcaaactga tcgaagtccc ggttgagtac
     5221 atcgcaggta aagtggttgc taaagactat attgatgagt ctaccggcga gctgatctgc
     5281 gcagcgaaca tggagctgag cctggatctg ctggctaagc tgagccagtc tggtcacaag
     5341 cgtatcgaaa cgctgttcac caacgatctg gatcacggcc catatatctc tgaaacctta
     5401 cgtgtcgacc caactaacga ccgtctgagc gcactggtag aaatctaccg catgatgcgc
     5461 cctggcgagc cgccgactcg tgaagcagcg gaaagcctgt tcgagaacct gttcttctcc
     5521 gaagaccgtt atgacctgtc tgcggttggt cgtatgaagt tcaaccgttc tctgctgcgc
     5581 gaagaaatcg aaggttccgg tatcctgagc aaagacgaca tcattgatgt tatgaaaaag
     5641 ctcatcgata tccgtaacgg taaaggcgaa gtcgatgata tcgaccacct cggcaaccgt
     5701 cgtatccgtt ccgttggcga aatggcggaa aaccagttcc gcgttggcct ggtacgtgta
     5761 gagcgtgcgg tgaaagagcg tctgtctctg ggcgatctgg ataccctgat gcctcaggat
     5821 atgatcaacg ccaagccgat ttccgcagca gtgaaagagt tcttcggttc cagccagctg
     5881 tctcagttta tggaccagaa caacccgctg tctgagatta cgcacaaacg tcgtatctcc
     5941 gcactcggcc caggcggtct gacccgtgaa cgtgcaggct tcgaagttcg agacgtacac
     6001 ccgactcact acggtcgcgt atgtccaatc gaaacccctg aaggtccgaa catcggtctg
     6061 atcaactctc tgtccgtgta cgcacagact aacgaatacg gcttccttga gactccgtat
     6121 cgtaaagtga ccgacggtgt tgtaactgac gaaattcact acctgtctgc tatcgaagaa
     6181 ggcaactacg ttatcgccca ggcgaactcc aacctggatg aagaaggcca cttcgtagaa
     6241 gacctggtaa cttgccgtag caaaggcgaa tccagcttgt tcagccgcga ccaggttgac
     6301 tacatggacg tatccaccca gcaggtggta tccgtcggtg cgtccctgat cccgttcctg
     6361 gaacacgatg acgccaaccg tgcattgatg ggtgcgaaca tgcaacgtca ggccgttccg
     6421 actctgcgcg ctgataagcc gctggttggt actggtatgg aacgtgctgt tgccgttgac
     6481 tccggtgtaa ctgcggtagc taaacgtggt ggtgtcgttc agtacgtgga tgcttcccgt
     6541 atcgttatca aagttaacga agacgagatg tatccgggtg aagcaggtat cgacatctac
     6601 aacctgacca aatacacccg ttctaaccag aacacctgta tcaaccagat gccgtgtgtg
     6661 tctctgggtg aaccggttga acgtggcgac gtgctggcag acggtccgtc caccgacctc
     6721 ggtgaactgg cgcttggtca gaacatgcgc gtagcgttca tgccgtggaa tggttacaac
     6781 ttcgaagact ccatcctcgt atccgagcgt gttgttcagg aagaccgttt caccaccatc
     6841 cacattcagg aactggcgtg tgtgtcccgt gacaccaagc tggggccgga agagatcacc
     6901 gctgacatcc cgaacgtggg tgaagctgcg ctctccaaac tggatgaatc cggtatcgtt
     6961 tacattggtg cggaagtgac cggtggcgac attctggttg gtaaggtaac gccgaaaggt
     7021 gaaactcagc tgaccccaga agaaaaactg ctgcgtgcga tcttcggtga gaaagcctct
     7081 gacgttaaag actcttctct gcgcgtacca aacggtgtat ccggtacggt tatcgacgtt
     7141 caggtcttta ctcgcgatgg cgtagaaaaa gacaaacgta cgctggaaat cgaagaaatg
     7201 cagctcaaac aggcgaagaa agacctgtct gaagaactgc agatcctcga agcgggtctg
     7261 ttcagccgta tccgtgctgt gctggtagcc ggtggcgttg aagctgagaa gctcgacaaa
     7321 ctgccgcgcg atcgctggct ggagctgggc ctgacagacg aagagaaaca aaatcagctg
     7381 gaacagctgg ctgagcagta tgacgaactg aaacacgagt tcgagaagaa actcgaagcg
     7441 aaacgccgca aaatcaccca gggcgacgat ctggcaccgg gcgtgctgaa gattgttaag
     7501 gtatatctgg cggttaaacg ccgtatccag cctggtgaca agatggcagg tcgtcacggt
     7561 aacaagggtg taatttctaa gatcaacccg atcgaagata tgccttacga tgaaaacggt
     7621 acgccggtag acatcgtact gaacccgctg ggcgtaccgt ctcgtatgaa catcggtcag
     7681 atcctcgaaa cccacctggg tatggctgcg aaaggtatcg gcgacaagat caacgccatg
     7741 ctgaaacagc agcaagaagt cgcgaaactg cgcgaattca tccagcgtgc gtacgatctg
     7801 ggcgctgacg ttcgtcagaa agttgacctg agtaccttca gcgatgaaga agttatgcgt
     7861 ctggctgaaa acctgcgcaa aggtatgcca atcgcaacgc cggtgttcga cggtgcgaaa
     7921 gaagcagaaa ttaaagagct gctgaaactt ggcgacctgc cgacttccgg tcagatccgc
     7981 ctgtacgatg gtcgcactgg tgaacagttc gagcgtccgg taaccgttgg ttacatgtac
     8041 atgctgaaac tgaaccacct ggtcgacgac aagatgcacg cgcgttccac cggttcttac
     8101 agcctggtta ctcagcagcc gctgggtggt aaggcacagt tcggtggtca gcgtttcggg
     8161 gagatggaag tgtgggcgct ggaagcatac ggcgcagcat acaccctgca ggaaatgctc
     8221 accgttaagt ctgatgacgt gaacggtcgt accaagatgt ataaaaacat cgtggacggc
     8281 aaccatcaga tggagccggg catgccagaa tccttcaacg tattgttgaa agagattcgt
     8341 tcgctgggta tcaacatcga actggaagac gagtaattct cgctcaaaca ggtcactgct
     8401 gtcggggtaa aacccggcag cggattgtgc taactccgac gggagcaaat ccgtgaaaga
     8461 tttattaaag tttctgaaag cgcagactaa aaccgaagag tttgatgcga tcaaaattgc
     8521 tctggcttcg ccagacatga tccgttcatg gtctttcggt gaagttaaaa agccggaaac
     8581 catcaactac cgtacgttca aaccagaacg tgacggcctt ttctgcgccc gtatctttgg
     8641 gccggtaaaa gattacgagt gcctgtgcgg taagtacaag cgcctgaaac accgtggcgt
     8701 catctgtgag aagtgcggcg ttgaagtgac ccagactaaa gtacgccgtg agcgtatggg
     8761 ccacatcgaa ctggcttccc cgactgcgca catctggttc ctgaaatcgc tgccgtcccg
     8821 tatcggtctg ctgctcgata tgccgctgcg cgatatcgaa cgcgtactgt actttgaatc
     8881 ctatgtggtt atcgaaggcg gtatgaccaa cctggaacgt cagcagatcc tgactgaaga
     8941 gcagtatctg gacgcgctgg aagagttcgg tgacgaattc gacgcgaaga tgggtgcgga
     9001 agcaatccag gctctgctga agagcatgga tctggagcaa gagtgcgaac agctgcgtga
     9061 agagctgaac gaaaccaact ccgaaaccaa gcgtaaaaag ctgaccaagc gtatcaaact
     9121 gctggaagcg ttcgttcagt ctggtaacaa accagagtgg atgatcctga ccgttctgcc
     9181 ggtactgccg ccagatctgc gtccgctggt tccgctggat ggtggtcgtt tcgcgacttc
     9241 tgacctgaac gatctgtatc gtcgcgtcat taaccgtaac aaccgtctga aacgtctgct
     9301 ggatctggct gcgccggaca tcatcgtacg taacgaaaaa cgtatgctgc aggaagcggt
     9361 agacgccctg ctggataacg gtcgtcgcgg tcgtgcgatc accggttcta acaagcgtcc
     9421 tctgaaatct ttggccgaca tgatcaaagg taaacagggt cgtttccgtc agaacctgct
     9481 cggtaagcgt gttgactact ccggtcgttc tgtaatcacc gtaggtccat acctgcgtct
     9541 gcatcagtgc ggtctgccga agaaaatggc gctggagctg ttcaaaccgt tcatctacgg
     9601 caagctggaa ctgcgtggtc ttgctaccac cattaaagct gcgaagaaaa tggttgagcg
     9661 cgaagaagct gtcgtttggg atatcctgga cgaagttatc cgcgaacacc cggtactgct
     9721 gaaccgtgca ccgactctgc accgtctggg tatccaggca tttgaaccgg tactgatcga
     9781 aggtaaagct atccagctgc acccgctggt ttgtgcggca tataacgccg acttcgatgg
     9841 tgaccagatg gctgttcacg taccgctgac gctggaagcc cagctggaag cgcgtgcgct
     9901 gatgatgtct accaacaaca tcctgtcccc ggcgaacggc gaaccaatca tcgttccgtc
     9961 tcaggacgtt gttctgggtc tgtactatat gacccgtgac tgtgttaacg ccaaaggcga
    10021 aggcatggtg ctgactggcc cgaaagaagc agaacgtctg tatcgctctg gtctggcttc
    10081 tctgcatgcg cgcgttaaag tgcgtatcac cgagtatgaa aaagatgcaa acggtgaatt
    10141 agtagcgaaa accagcctga aagacacgac tgttggccgt gccattctgt ggatgattgt
    10201 accgaaaggt ctgccttact ccatcgtcaa ccaggcgctg ggtaaaaaag caatctccaa
    10261 aatgctgaac acctgctacc gcattctcgg tctgaaaccg accgtaattt ttgcggacca
    10321 gatcatgtac accggcttcg cctatgcagc gcgttctggt gcatctgttg gtatcgatga
    10381 catggtcatc ccggagaaga aacacgaaat catctccgag gcagaagcag aagttgctga
    10441 aattcaggag cagttccagt ctggtctggt aactgcgggc gaacgctaca acaaagttat
    10501 cgatatctgg gctgcggcga acgatcgtgt atccaaagcg atgatggata acctgcaaac
    10561 tgaaaccgtg attaaccgtg acggtcagga agagaagcag gtttccttca acagcatcta
    10621 catgatggcc gactccggtg cgcgtggttc tgcggcacag attcgtcagc ttgctggtat
    10681 gcgtggtctg atggcgaagc cggatggctc gatcatcgaa acgccaatca ccgcgaactt
    10741 ccgtgaaggt ctgaacgtac tccagtactt catctccacc cacggtgctc gtaaaggtct
    10801 ggcggatacc gcactgaaaa ctgcgaactc cggttacctg actcgtcgtc tggttgacgt
    10861 ggcgcaggac ctggtggtta ccgaagacga ttgtggtacc catgaaggta tcatgatgac
    10921 tccggttatc gagggtggtg acgttaaaga gccgctgcgc gatcgcgtac tgggtcgtgt
    10981 aactgctgaa gacgttctga agccgggtac tgctgatatc ctcgttccgc gcaacacgct
    11041 gctgcacgaa cagtggtgtg acctgctgga agagaactct gtcgacgcgg taaaagtacg
    11101 ttctgttgta tcttgtgaca ccgactttgg tgtatgtgcg cactgctacg gtcgtgacct
    11161 ggcgcgtggc cacatcatca acaaaggtga agcaatcggt gttatcgcgg cacagtccat
    11221 cggtgaaccg ggtacacagc tgaccatgcg tacgttccac atcggtggtg cggcatctcg
    11281 tgcggctgct gaatccagca tccaggtgaa aaacaaaggt agcatcaagc tcagcaacgt
    11341 gaagtcggtt gtgaactcca gcggtaaact ggttatcact tcccgtaata ctgaactgaa
    11401 actgatcgac gaattcggtc gtaccaaaga aagctacaaa gtaccttacg gtgcggtact
    11461 ggcgaaaggc gatggcgaac aggttgctgg cggcgaaacc gttgcaaact gggacccgca
    11521 caccatgccg gttatcaccg aagtaagcgg ttttgtacgc tttactgaca tgatcgacgg
    11581 tcagaccatt actcgtcaga cagacgaatt gaccggtctg tcttcgctgg tggttctgga
    11641 ttccgcagaa cgtacagcag gtggtaaaga tctgcgtccg gcactgaaaa tcgttgatgc
    11701 tcagggtaac gacgttctga tcccaggtac cgatatgcct gcgcagtact tcctgccggg
    11761 taaagcgatt gttcagctgg aagatggcgt acagatcagc tctggtgaca ccctggcgcg
    11821 tattccgcag gaatccggcg gtaccaagga catcaccggt ggtctgccgc gcgttgcgga
    11881 cctgttcgaa gcacgtcgtc cgaaagagcc ggcaatcctg gctgaaatca gcggtatcgt
    11941 ttccttcggt aaagaaacca aaggtaaacg tcgtctggtt atcaccccgg tagacggtag
    12001 cgatccgtac gaagagatga ttccgaaatg gcgtcagctc aacgtgttcg aaggtgaacg
    12061 tgtagaacgt ggtgacgtaa tttccgacgg tccggaagcg ccgcacgaca ttctgcgtct
    12121 gcgtggtgtt catgctgtga ctcgttacat cgttaacgaa gtacaggacg tataccgtct
    12181 gcagggcgtt aagattaacg ataaacacat cgaagttatc gttcgtcaga tgctgcgtaa
    12241 agctaccatc gttaacgcgg gcagctccga cttcctggaa ggcgaacagg ttgaatactc
    12301 tcgcgtcaag atcgcaaacc gcgaactgga agcgaacggc aaagtgggtg caacttactc
    12361 ccgcgatctg ctgggtatca ccaaagcgtc tctggcaacc gagtccttca tctccgcggc
    12421 atcgttccag gagaccactc gcgtgctgac cgaagcagcc gttgcgggca aacgcgacga
    12481 actgcgcggc ctgaaagaga acgttatcgt gggtcgtctg atcccggcag gtaccggtta
    12541 cgcgtaccac caggatcgta tgcgtcgccg tgctgcgggt gaagctccgg ctgcaccgca
    12601 ggtgactgca gaagacgcat ctgccagcct ggcagaactg ctgaacgcag gtctgggcgg
    12661 ttctgataac gagtaatcgt taatccgcaa ataacgtaaa aacccgcttc ggcgggtttt
    12721 tttatggggg gagtttaggg aaagagcatt tgtcagaata tttaaggaat ttctgaatac
    12781 tcataatcaa tgtagagatg actaatatcc tgaaactgac tgaactaatt gagtcaaact
    12841 cggcaaggat tcgatactat tcctgtgtaa ctttcttaag gaacgagaat gaaacaggaa
    12901 gtggaaaagt ggcgaccttt tggacatccg gatggtgata ttcgtgattt atcatttctt
    12961 gatgctcatc aggctgtcta cgttcagcat catgagggca aagagccttt agagtatcgc
    13021 ttttgggtta cctactctct tcactgcttc acaaaagatt atgaacatca gacgaacgaa
    13081 gaaaaacaat cgttaatgta ccacgcgcct aaagaatctc gtcccttctg ccagcaccgt
    13141 tataacttag cgcgcacaca cttaaaaaga actattttgg cgctgccaga aagcaacgtt
    13201 attcatgccg ggtatggtag ctatgccgtg attgaggtgg acttagacgg aggagataag
    13261 gcattttact ttgttgcgtt cagggctttc agggaaaaga aaaaactccg tttgcatgta
    13321 actagcgctt atcccatttc tgaaaaacag aaaggtaaat cagtgaaatt tttcaccatt
    13381 gcctacaact tattgagaaa taagcagctt cctcagccct caaaataaca aaacccacct
    13441 taaggtgggt ttcgccagag aattatctct ggtattcaga acgccattac cggactttgc
    13501 cttgaccttg cgataatcgc aggttgcggg atgtctgaat ttcttcagtc tgctgcatcc
    13561 tggaagatga gaacatgtgt tcttattttc gtctctatca tagttgagta tttactctct
    13621 tacaatcaga tctctttcat tgctcaacag gcgatggctt cagactttgc attacggaat
    13681 ttttaagaaa ggcagggcga aacgaggaag aagcttttcg ccctggacaa cattcctgct
    13741 gacggcacta ccataaaaaa acacaacgct ttcaacaacc ttgcgttttt catcttccgt
    13801 agcggctcgg aataaattta cgttcttaca ttccgtctca tagtctttgc gaggcccgtc
    13861 ccagatagct gtcccagtct ttccataccg gctgcaaacc ctgagcgatt aacgcggcag
    13921 caaccgcttc cggtctgcga tcgtcgtgcg gtgagaactg ttccaactcg gggtgattat
    13981 cggcatagcc acctggctgc gttttcgaga aggcgctgac gttattgatc gccagcggaa
    14041 taacgcgatc gcgaaaccac ggtgattccc gcgtggagag tgacagttca atctccggtg
    14101 caagcagtcg gaaggcgcag atggtttgca ctaactggcg ttcatccata atcgacgcag
    14161 gctcaatgcc gccagtacac gggcgcaggc gcggaaagga gacagagtaa cggctttgcc
    14221 agtaatgctg ttgcagccat agcaaatgtt cggcaaccat atagcagtca acgcgccagt
    14281 tgtcggaaag gccaattagc gcgccgaggc ctatcttatc aatccccgca cgccccagcc
    14341 gatccggcgt ttccagccgc cagaagaagt cctgtttttt tcctttcaga tgatggcggg
    14401 cataagtcgc ctcgtgatat gtctcctgat aaaccatcac gccatccaga ccaagctgct
    14461 ttaactcggc gtattccgtc tccgccagcg gttgcacttc catttgtagt gaagagaact
    14521 gttcacgcag ggcggggaga tgacgacgaa agtaatccat ccccactttc gcctgatgtt
    14581 caccagtgac taatagcaga tgttcaaagc ccatctcccg tatagcggcg ctttccctgg
    14641 caatatccgc ttcatccagc gttttgcgct tgatgcgatt actcatggaa aatccgcagt
    14701 acgtgcagtc gttagcgcaa agattggaaa gataaagcgg gacgtagaaa ctaactgtgt
    14761 tgccaaatcg ctgacgggtc agacgctgcg cccgttgggc cagttgttcc agatagccac
    14821 tggcggctgg cgataacagc gccatcatat cgtcgcgggt gaattgcgag gcatttagcg
    14881 cccgctctac gtcaacagcc gttttgccgt tgatacgcag gcggatgtcg tcccagtcca
    14941 gttgtcgcca gcgatcgctg aaggttttca tgccgatgcc tccagaaatc cagtcagcgg
    15001 gctggtggca tgagcaaaat gactgcggct gcccggtccg gactgacgtg ccagcaggcc
    15061 tgcttctacc gccagacgaa atgccttcgc catgttgacg ggatcgtccg cgacggcaat
    15121 tgccgtattc actaacaccg cgtcggcccc catttccagc gcctgcgcgg catggctggg
    15181 aacgccgatg ccagcatcga caaccaccag cactgtggcc tgctggataa taatctccag
    15241 catggcgcgg gtttccagtc cctgattcga gccaatcggc gcgccgagcg gcatcaccgc
    15301 tgcacagccg acttcttcca gacgtttaca caataccgga tcggccccgc agtaaggcag
    15361 cacgacaaat ccctgttgta ccagcgtttc ggcggctttc agggtttcga tgggatcggg
    15421 caacagccag cgggcgtcag ggtgaatctc taattttaac cagtttgtgc ctaacgcttc
    15481 acgagccaga tgggcggcga aaatggcttc ttccgctgtt ttcgccccgg atgtatttgg
    15541 cagcagggtc acacccgccg cgataagcgg ttcgaggata gcgtcgttgt gctggcgcaa
    15601 gtcgacacgt ttcatcgcca gtgtcaccag ctggctgccg gaagcgcgga tcgcctccac
    15661 catcagttgt gaagaagcga atttccctgt gccggtaaac agatgtgaat caaacgtttt
    15721 gtccgcaata cgtaacattt caaccccctg caataacctg aaaaagcagg atctggtcgc
    15781 catcctgcac gatatgttgc gcccactgct cacgcgggac gatttgctga ttaatcgcca
    15841 gagccgcgcc cgcttgtcgt tggtcgagtt gctccagtag ttcgtgaaca gtttgcccgg
    15901 cggcgcactg catcggttga tcgttaaaca ggatctgcat tgcttcctcc gcataccggg
    15961 caaccactgg cgcggcgcaa cgccaggctg cgccactggc tcgatttacc gtcgaacagt
    16021 cggagttctc ccgcaggtgt ctctataccg cttaataact taatggcttc cagtgcctgc
    16081 aaagtgccca taaccccgac caccgggcca accacgcccg ccgtgcggca gttgcgttct
    16141 ggctcctggt tatctggcca caggcagcgg taacacccct gctcccaggg cggcgtcagt
    16201 accatcaact gaccgccaaa tccgaccgcg ctggcagtga taagcggcgt gttgagtgcc
    16261 acgcaggcgg cattaatctc ctggcgagtc gccatattgt cggtacagtc gagcaccaca
    16321 tcggcccgtg caaccgcatc ttttaacgcc tcacccgtta accgttgttg taatgctgtc
    16381 agttgaatgt cgggattcaa ctgtgtcagt cgctgttggc tgacctgcga tttcgggcga
    16441 tcgatatctt cagtggtaaa gaggatttgt cgttgcagat tgcttaaatg cacatcgtcg
    16501 tcatctgcca gtaccagcgt cccgacgcca gcgcccgcca ggtatagcgc agcaggtgta
    16561 cccagcccgc caagaccgat aatcagcacc tggctgtcga gcagtttttg ctgcccgtca
    16621 agagcgatat cgtcgagcag gatttggcgg ctataacgca taaaatcacg gtcattcatc
    16681 gccaactcct gcaatttcca gcaactgtgc cgttgccaaa cgccagtctg cggcttgagt
    16741 aatggcgctg acgacggcga tactgccgac acccgttgct atcaccgcag gcgcgcgtgc
    16801 cagactgaca ccgccaatcg ccacggtggg ataatccgcc agtcgctcaa catgccgtgc
    16861 cagctgttcc agcccctgcg gtgcagaagg catctgtttg gtttgcgtcg ggaacacatg
    16921 tcccagcgcg atataagagg ggcgtgctgc cagcgcgacg tcgatttcca tatcgtcatg
    16981 tgtcgaaaca cccagccgca ggcctgccgc gcggatggca ttgagatcgg tggcttgcaa
    17041 atcttcctgc cccaaatgga cgccatacgc ctgatgcttg atcgcgagcc gccagtaatc
    17101 gttgataaac aatcgcgcgt tatagcggcg gcccagcgca attgccgcca cgacatcggc
    17161 ttccacctct tcatcgcgcc gatctttgat gcgtagctgg agagtacgta cgcctgcatc
    17221 caacagacgt tcgatccact gtacgctgtc caccactggg tacagtccta aacgaaaagg
    17281 tacaggagga aaatcaggct gatacatcac gcttcctcct tacgcaggta gatttctccg
    17341 cctctggcac ggaagttctc cgacatatcc gccattccca tttcaatagt ttgcgtggcg
    17401 gcgtaatcac gcacttcctg gctgattttc atcgagcaga atttcggccc acacatggag
    17461 caaaaatggg cgactttacc tgactcttgc ggcagggttt catcgtgata agcgcgggcg
    17521 gtaaacgggt cgagggccag attaaactgg tcttcccagc gaaattcgaa gcgggctttc
    17581 gacatggcgt tatcgcgaat ttgcgcgccc ggatgccctt tcgccaggtc agcggcgtgg
    17641 gcggcaatct tataggtgat aagcccctgc ttaacatctt ctttattggg cagacccaga
    17701 tgctcttttg gcgttacgta acagagcatc gcgcagccaa accagccaat catcgccgca
    17761 ccaatccccg acgtgaagtg gtcatagccc ggcgcaatat cggtagttag cggccccaga
    17821 gtgtaaaacg gcgcttcgtg gcagtgctct aactcctcgg tcatattgcg gcggatcatc
    17881 tgcatcggca cgtggcctgg gccttcaatc atcacctgca cgtcatattc ccaggcaatt
    17941 ttggtcagtt cgcccagcgt atgcagctcg gcaaactgcg cttcatcgtt ggcgtcctga
    18001 atagaaccgg ggcgcagacc gtcgcccagc gacagcgaaa cgtcataagc ggcacagatt
    18061 tcacaaattt cgcggaagtg ttgatagagg aaattttcct gatgatggga gaggcaccat
    18121 ttcgccataa tcgaaccgcc gcgagagacg ataccggtca ggcgttttgc ggtcatcggc
    18181 acatagcgca gcagtacgcc cgcatggata gtgaagtaat ccacaccttg ctcggcctgt
    18241 tccagcagcg tgtcgcggaa cgcttcccag gtaagatctt cggcgatccc gttaaccttc
    18301 tccagcgcct ggtagatcgg cactgtaccg atcggcaccg ggctgttacg caaaatccac
    18361 tcgcgggttt cgtgaatata gcgaccggtg gagagatcca tcaccgtatc cgctccccag
    18421 cgcgtggacc ataccagctt ttccacttct tcttcgatgg aagaggtgac cgccgagttg
    18481 ccgatattgg cgttaacttt taccaggaag ttacggccaa taatcatcgg ctccgattcc
    18541 ggatgattaa tgttggccgg gataatcgca cgtccggcag caacttcatc acggacaaat
    18601 tccgcagtga tattttccgg cagacgtgcg ccaaagctca ttcccggatg ctggtggcgt
    18661 aaaacttcgc tacgtatgcg ctcgcggccc atattctcgc ggatggcgat gaattccatt
    18721 tccggcgtga tgatgccctg gcgggcgtag tgcagttggg tgacacggcg tcctgctttg
    18781 gcgcgttttg gtgttagtac gccgctaaaa cgcagttcgt cgaggccatc atctgccagc
    18841 cgcgctttag tgtaatcgga actgcgcacg gtaagttctt cggtatcgcc gcgcgcatcg
    18901 atccacggct ggcgtagttt tgccagccct tgctgcacgt taatggcaat ctgcggatca
    18961 ccatacgggc cggaggtgtc gtagaccgga atcgcttcgt tttcttcgta ctgcggctgt
    19021 tctttgctac cgccaattag cgtcgggcta agctggatct cacgcatcgg cacgcgaacg
    19081 ccggggtgcg tgccagtgat ataaatacgt tttgagttgg gaaaggcggt gccttccagg
    19141 gtgtcgataa aatgttgggc gtgggcgcgc tgttcgcggc gggtcagttt tgttgcagac
    19201 atagctcatt ccaaaagtta aggacgtggc ttgtcagacg acggatgaag caagagacga
    19261 tcgccgcaaa ggcgatgcga tagcagatta actcttgttc ccttcgcagg tattagcctg
    19321 atcaggttcc gcggatcccg aataaacggt ctcagccagt taaggcactc cgacaagaaa
    19381 ttagccccgc aaatggggca ttgaatgtaa attacgcgtt aacagcacag aactcaagca
    19441 ggatgtttga cgcgggcggc gtcaagcacc agcagaatca gcttatcttc cagcacaaag
    19501 cgcgcttcca gcgcctcgcc gatgtcagat aaaacctgtt gaaactcaag gtaattatca
    19561 tgatcgatag cggtttccag gctggaatcg tagtaatcca taatctgttg agtattggct
    19621 tcaagttgcg gccaaatctt cgcggcgcgc gcgagttgcc cgttgccttc cagcttatga
    19681 agaatgcgct cataaatact gaaatgcccg gcagacaagt aatcgaccag gctctgacaa
    19741 aaatcatcaa gggctttttc gtttagcctc atgtacgatt ctttgccagg cttaatgcca
    19801 accagattgt agtaagccac gagcagatgc ttacgtacat gtagccagcg atcaaccagt
    19861 ttgttacttc ctctgacgcg ctccgtcagg ttatcgagct ggttaagcat gattgactcc
    19921 gcaagtttgt attcaaaaac tgctcagtga gaaatgtaaa aaccatgtta aacatgccag
    19981 tgatgcaaag gtagtgcaag agctatggat cgtataattg aaaaattaga tcacggctgg
    20041 tgggtcgtca gccatgaaca aaaattatgg ttgccgaagg gagaattgcc atatggcgaa
    20101 gcggcaaatt tcgatcttgt gggtcagcgc gcactacaaa tcggcgaatg gcagggggaa
    20161 cctgtttggt tagtacaaca gcagcggcgt cacgatatgg ggtcggtacg tcaggtcatt
    20221 gatctcgatg ttgggctgtt tcaactggcc ggacgaggcg tacaactggc ggagttttac
    20281 cgatcgcata aatactgtgg ttactgcggg catgaaatgt atccgagcaa aaccgaatgg
    20341 gcgatgctgt gcagccattg ccgtgagcgt tactacccgc aaatcgcccc ctgcattatt
    20401 gttgccatcc gtcgcgatga ttcgatcctc ctcgcccagc atacccgcca tcgtaacggt
    20461 gtccatacag tacttgccgg attcgtcgaa gtgggcgaaa ccctcgagca ggcagtcgcg
    20521 cgggaagtga tggaagagag cggaattaaa gttaaaaact tgcgttacgt gacttctcag
    20581 ccgtggccgt ttcctcagtc tttaatgacc gcgtttatgg cggaatatga cagcggcgac
    20641 atcgtgatcg acccgaaaga attgctcgag gcgaactggt atcgctatga cgatttgccg
    20701 ttactcccgc cgcccggcac cgtagcgcgc cgtctgatag aagatacggt ggcgatgtgt
    20761 cgggcagagt atgagtgatg atacactgac cgcctgacgc actaaggaac agccaaaatg
    20821 accgaactta aaaacgatcg ttatctgcgg gcgctgctgc gccagcccgt tgatgtcact
    20881 ccagtatgga tgatgcgcca ggcgggtcgc tatctaccgg aatataaagc cacgcgcgcc
    20941 caggcgggcg attttatgtc gctgtgcaaa aacgccgagc tggcgtgcga agtgactttg
    21001 caaccgctgc gtcgctaccc gctggatgcg gcgatcctct tttccgatat cctcaccgtg
    21061 ccggacgcga tggggttagg gctctatttt gaagccggag aaggtccgcg ttttacctcg
    21121 ccagtcacct gcaaagccga cgtcgataaa ctgccaattc cggacccgga agatgagctg
    21181 ggttacgtga tgaacgcggt gcgtaccatt cgtcgcgaac tgaaaggcga agtgccgctg
    21241 attggttttt ccggcagccc gtggacgctg gcaacctaca tggtggaagg cggcagcagc
    21301 aaagccttca ccgtgatcaa aaaaatgatg tatgccgatc cgcaggcgct gcacgctcta
    21361 ctcgataaac tggcgaaaag cgtcactttg tatctgaatg cgcagattaa agccggtgct
    21421 caggctgtga tgattttcga cacctggggc ggcgtgctta ccgggcgcga ttatcaacag
    21481 ttctcgcttt attacatgca taaaattgtt gatggtttac tgcgtgaaaa cgacggtcgc
    21541 cgcgtaccgg tcacgctgtt taccaaaggc ggcggacagt ggctggaagc catggcagaa
    21601 accggttgcg atgcgctggg cctcgactgg acaacggaca tcgccgatgc gcgccgccgt
    21661 gtgggcaata aagtcgcgtt gcagggtaat atggatccgt cgatgctgta cgcgccgcct
    21721 gcccgcattg aagaagaagt agcgactata cttgcaggtt tcggtcacgg cgaaggtcat
    21781 gtctttaacc ttggtcacgg cattcatcag gatgtgccgc cagaacatgc tggcgtgttc
    21841 gtggaggcag tgcatcgact gtctgaacag tatcaccgct aaggagtgat tatggatctc
    21901 gcgtcattac gcgctcaaca aatcgaactg gcttcttctg tgatccgcga ggatcgactc
    21961 gataaagatc caccggatct gatcgccgga gccgatgtcg ggtttgagca gggcggagaa
    22021 gtgacgcgag cggcgatggt gctgctgaaa tatccctcgc ttgagctggt ggagtataaa
    22081 gttgcccgca tcgccaccac catgccttac attccaggtt ttctttcctt ccgcgaatat
    22141 cctgcgctgc tggcagcgtg ggagatgctg tcgcaaaagc cggatttagt gtttgtcgat
    22201 ggtcatggga tctcgcatcc tcgccgtctt ggcgtcgcca gccattttgg tttgatggtg
    22261 gatgtgccaa cgatcggcgt ggcgaaaaaa cggctctgcg gtaaattcga accgctctcc
    22321 agcgaaccgg gcgcgctggc cccactgatg gataaaggcg agcagctggc ctgggtctgg
    22381 cgcagcaaag cgcgctgtaa cccgttgttt atcgctaccg gccatcgggt cagcgtggac
    22441 agcgcgctgg cgtgggtaca acgctgcatg aaaggctatc gtctgccgga gccaacgcgc
    22501 tgggcggacg cggtggcctc ggaacgtccg gcgttcgtgc gctatacagc aaatcagccc
    22561 taattcaggt aaactgcgga taatttccgt atttgagaac tcaacatgtt acaaaaccca
    22621 attcatctgc gtctggagcg cctggaaagc tggcagcatg tcactttcat ggcttgctta
    22681 tgcgaacgca tgtaccccaa ttacgccatg ttctgccagc aaaccggttt tggtgatggg
    22741 caaatttacc gtcgcattct cgatctcatc tgggaaacgc tgaccgttaa agacgcaaaa
    22801 gtaaatttcg acagccaact ggagaaattt gaagaagcga ttccttcagc cgacgatttc
    22861 gatctgtacg gcgtttatcc ggcaatcgat gcctgcgtgg cgttaagtga actggtccat
    22921 tcgcgtttga gtggtgaaac gctcgaacac gcggtggaag tgagtaagac ctccatcacg
    22981 accgttgcga tgctggaaat gactcaggct ggtcgcgaaa tgagcgatga agagcttaaa
    23041 gaaaacccag ctgtagagca agaatgggac attcagtggg aaatattccg acttttagct
    23101 gagtgcgaag aacgcgatat cgagctgata aaaggcctta gggcagacct gcgtgaggcg
    23161 ggtgagagca atattggtat aatttttcag caataagacc agaaaacgtg atttaacgcc
    23221 tgatttgtcg tacctggagt cttccctttc gccccccgtc tggtctacat ttggggggcg
    23281 aaaaaaagtg gctatcggtg cgtgtatgca ggagagtgct attctggcat ttccgtcgca
    23341 ctcgatgctt agcaagcgat aaacacattg taaggataac ttatgaacaa gactcaactg
    23401 attgatgtaa ttgcagagaa agcagaactg tccaaaaccc aggctaaagc tgctctggag
    23461 tccactctgg ctgcaattac tgagtctctg aaagaaggcg atgctgtaca actggttggt
    23521 ttcggtacct tcaaagtgaa ccaccgcgct gagcgtactg gccgcaaccc gcagaccggt
    23581 aaagaaatca aaattgccgc agctaacgta ccggcatttg tttctggcaa ggcactgaaa
    23641 gacgcagtta agtaagattg cgtggcagtg aacagtttta acgaaggggt ggtttcaccc
    23701 cttttgtctt tctggcgtcg atcattgatg ctggctggcg ctctgcttct cactgcctgt
    23761 agtcataact cttcacttcc tccctttacc gccagtggat ttgctgaaga ccagggcgca
    23821 gtacgcatct ggcgaaaaga cagcggcgat aatgtgcatc tgcttgccgt gtttagcccg
    23881 tggcgcagtg gcgataccac gacgcgagag tatcgctggc agggcgataa cctcacgctc
    23941 atcaatatca atgtttacag caaaccgccg gtgaacattc gcgcgcgttt tgacgatcgc
    24001 ggtgatctga gctttatgca acgtgaatcc gatggggaaa agcagcagct ttctaacgac
    24061 caaatcgatt tataccgtta tcgtgctgat cagatccgcc agattagcga tgccttacgt
    24121 caggggagag tcgtgctgcg ccaggggcgc tggcatgcga tggaacagac cgtgaccacc
    24181 tgcgaagggc aaaccattaa acctgattta gattcgcagg cgatagcgca tatcgagcgc
    24241 cgccagagcc gctcttctgt tgatgtcagc gtggcatggc tggaagcgcc cgaaggttcg
    24301 caattactgt tagtggcaaa ctctgatttc tgtcgctggc aacccaacga gaaaacgttc
    24361 tgatttacca gtggcccata cccatatgac cgccaccacc gcagccgccg tagcccatgc
    24421 ccattccggc tccgcgcgga atacccgctt cagccatcgc gatatctcgt ttcacccgta
    24481 actcatctaa cgactgacgc aaattctcca tctctttggc gaccgcgtta attttgctgc
    24541 tatccggtgg gttcgcggct aacagggcat tgtattcata acgcttcgtc accagttgct
    24601 gttgcagtgc gctgctttga gcgtaaaagt cattatggat tttctgccac gctgtctgtt
    24661 gttcgctggt caaaggcgcg gcattttgct gccacatacc gtgtccgccg tgagcaaatg
    24721 cagatgtcga tcccatcgcc attgctgaaa gcgccatcat taccagggca attttcgtgt
    24781 tccgtttcat ggttaatcct ccagtggttg tcttacttcg ggtattgcat cttccgtgcc
    24841 aacgatgaaa cgctgatatg acgggtaatc tggcatgata aacgagtaaa aatgactcgc
    24901 ctgctgcggg tagcgagtca tttttactca ttgaaactta agcctttgtg ttacagcgca
    24961 gggtaagcgc tgataaaaga tggcatgatt tctgctgtca gaaagggatg agcaggcaaa
    25021 gaagaagatg cgttttatgc aacgttctaa agactcctta gctaaatggt taagcgcgat
    25081 cctccccgtg gtcattgttg ggctggtagg gttgtttgcg gtgacggtga ttcgcgatta
    25141 tgggcgcgag actgccgccg ccagacaaac gctgctggaa aaaggcagtg tacttattcg
    25201 cgctcttgaa tccggctcgc gcgtcggcat ggggatgcgc atgcatcatg cgcagcagca
    25261 ggccttactg gaagaaatgg ccgggcagcc tggagtacgt tggtttgcgg tcacggatga
    25321 acaaggaaca atcgtgatgc atagcaactc cggcatggtg ggaaaacagc tttattcccc
    25381 gcaggaaatg cagcagttac atcctggaga tgaagaagcg tggcggcgga tcgatagcgc
    25441 agacggcgag cctgttctgg aaatttatcg ccagtttcaa ccgatgtttg ctgctggaat
    25501 gcaccggatg cgccatatgc agcagtatgc cgcgacacca caagcaattt tcatcgcttt
    25561 cgacgccagt aatattgtga gtgccgaaga tcgtgagcag agaaacaccc tgattatcct
    25621 cttcgccctg gcgacggtct tgctggcaag cgtgttgtca ttcttctggt atcgccgcta
    25681 tctgcgctcg cgccagctgt tgcaggatga aatgaagcgc aaagagaagc tggtagctct
    25741 ggggcatctt gcggcaggcg ttgcccacga aatccgtaat ccactttcct caattaaagg
    25801 gctggcgaaa tactttgccg aacgcgcgcc agcaggggga gaagcgcatc aattggcgca
    25861 ggtgatggcg aaagaagccg accgtttaaa ccgcgtggta agcgagttgc tggaactggt
    25921 taagccaacg catctggctt tgcaggcggt ggatctcaac acgctgatta accactcatt
    25981 acagctggta agccaggatg caaacagccg ggagatccag ttacgcttta ccgccaacga
    26041 cacattaccg gaaattcagg ccgatccgga caggctgact caggtcctgt tgaatctcta
    26101 tctcaatgct attcaggcga ttggtcagca tggcgtgatt agcgtgacgg tcagcgaaag
    26161 cggcgcgggc gtgaaaatca gcgttaccga cagcggtaag ggaattgcgg cagatcagct
    26221 tgaagccatc ttcactccgt acttcaccac caaagccgaa ggcaccggat tggggctggc
    26281 ggtcgtgcat aatattgttg aacaacacgg tggtacaatt caggtcgcaa gccaggaggg
    26341 aaaaggctca acgttcaccc tctggcttcc ggtcaatatt acgcgtaagg acccacaagg
    26401 atgacgcacg ataatatcga tattctggtg gtggatgatg acattagcca ctgcactatt
    26461 ttgcaggctt tactgcgcgg ctggggctat aacgtcgcgc tggcgaacag cgggcgacag
    26521 gcgctggagc aggtgcggga acaggttttt gatcttgtgc tttgcgatgt gcgaatggcg
    26581 gagatggacg gcatcgccac gctgaaagag atcaaagcgt taaacccggc aattccggtg
    26641 ctgattatga ctgcgtactc cagcgtcgag acggcggtag aggcactgaa aactggggcg
    26701 ctggattatc tcatcaagcc gctggatttc gataacctac aggcgacgct ggaaaaggcg
    26761 ctcgcgcata cgcacagtat tgatgctgaa acacctgcgg tgactgccag ccagttcggt
    26821 atggtcggta aaagctcggc gatgcaacac ctgctcagtg aaatcgccct cgtcgcgcca
    26881 tcggaagcca cggtactgat ccacggcgat tccggcaccg gtaaagagct ggtcgccagg
    26941 gcgattcacg ccagtagcgc acgtagcgaa aaaccgctgg taacgctcaa ctgtgcggca
    27001 ctcaacgaat ccttgctgga atctgaattg ttcggtcacg aaaaaggggc gtttactgga
    27061 gccgataaac gccgggaagg gcgctttgtt gaggcggacg gcggcacgct gtttctcgat
    27121 gaaattggcg atatctcgcc gatgatgcag gtgcgtctgc tgcgtgcgat tcaggagcgc
    27181 gaagttcagc gtgtcggtag caaccagact atctcggttg atgtccggct gattgcggcg
    27241 acccatcgcg atcttgccgc agaggtgaat gccgggcgtt ttcgccagga tctctactat
    27301 cgcctgaatg tggtggcgat tgaagtacca tcgctgcggc aacggcggga agatatccct
    27361 ctgctggctg gccattttct gcagcgcttt gccgagcgta atcgcaaggc ggtaaaaggt
    27421 tttacgcccc aggcgatgga tctgttgatc cactacgact ggccgggaaa tattcgtgaa
    27481 ctggaaaacg cggtggaacg ggcggtggtg ctgctgaccg gggaatatat ttccgaacgc
    27541 gagctgccgc tggcgattgc cggtacgccg atcccgctgg ggcaaagtca ggatattcag
    27601 ccgctggtag aagtcgaaaa agaagtgatt ctggcggcac tggagaaaac gggcggcaac
    27661 aaaaccgagg ccgcccgtca gttagggatc acgcgcaaaa cgctattggc aaaactgtcg
    27721 cgttagttct gctcgcgttc gatagcgcgc cagccaatat ctttccggca gaagcagtcg
    27781 tcccagtgaa tatcggtcat taaggcataa gcgcgtttct gcgcttctgc cacggtatga
    27841 cccagcgcgg tgacgcacag tacgcgcccg ccgctggtca ctacctgctc gttatccgcc
    27901 agtttcgtgc ccgcgtggaa cactttgccg tcagccactt cttccagcgg caggccgtgg
    27961 atcacatcgc cggtgcggta atcgcccgga tatccacccg cagccatcac cacgccgaga
    28021 gaagcgcgtt catcccactc ggatgttttc tcgtccagct tcccttcaca ggctgccagg
    28081 cagagctcaa ccagatcgga cttcatgcgc agcataatcg gctgggtttc cggatcgcca
    28141 aagcggcagt taaattcgat aaccttcgga ttgccctgtt tgtcgatcat caggcccgcg
    28201 tagagaaaac cggtgtaggt gttgccttcc gccgccatgc ctttcacggt tggccagatg
    28261 atacgttcca tggtgcgctg atgaacttca tcggttacta ccggcgcggg ggagtaagcg
    28321 cccatcccgc ccgtgtttgg tccggtatct ttatcgccta cgcgtttgtg atcctggctg
    28381 gtagccatcg gcaacacatg ctcgccgtcc accatcacga taaagctcgc ttcttcgcca
    28441 tcgaggaact cttcgataac gatgcgatga cccgcgtcgc caaaagcgtt gcccgccagc
    28501 atatcgtgaa cagccgcttc cgcttcttcc agcgtcatcg ccacgataac gcctttcccg
    28561 gcagccagac cgtccgcttt aatgacgatt ggcgcgcctt tctcacgcag atacgccagc
    28621 gcaggttcta cctcggtgaa gttctggtat tccgccgtag ggatcttatg gcgggccagg
    28681 aaatctttgg taaacgcttt tgagccttcc agttgggccg cacctgcggt tgggccgaag
    28741 attttcagcc cggcggcgcg gaaggtatcg accacgcctt tcaccagcgg cgcttccggg
    28801 ccgacgatgg tcagatcaat cttttcgttt tgtgcgaaat ccaacagcgc cgggatatcg
    28861 gtcacgccaa tagcaacgtt ttgcagcgcg ggttccagtg cagtgcctgc attacccgga
    28921 gcaacaaaaa cagtctcaac cagcggcgac tgggccgctt tccaggccag cgcgtgctcg
    28981 cgcccgccgt taccaatcac taatactttc atctattgct ccattaatgg cggaagtggc
    29041 gcatgtcggt gaagagcatc gcaataccgt gctcgtcggc ggcggcaatc acttcgtcat
    29101 cacggatgga accgccaggc tggattacgc aggtcacgcc cgcagcggcg gcggcatcaa
    29161 taccgtcgcg gaacgggaag aacgcgtcag aagccatcga ggaacctttc acttccaggc
    29221 cttcatcggc agctttaata ccggcgattt tcgcggagta cacgcggctc atctggcccg
    29281 cgccaatacc gatggtcata ttgtttttgg catagacgat agcattggat ttcacgaact
    29341 tcgccacttt ccagcagaac agcgcatcgc gcagttcctg ttcggtcggc tgacgttggg
    29401 tgacgacgcg cagttcttcc gcaccgacca tccccaggtc acgatcctga accagcagac
    29461 cgccgttcac gcgtttgaaa tcaagacccg gaacacgctc gccccactga ccgcaggtca
    29521 gaacgcgtac gttctgcttg gcggcggtga ttttcagggc ttcttcgctg gcggaaggcg
    29581 caataatcac ttcgacaaac tgacgagaaa tgatggcctg tgcggattcc gcatccagct
    29641 cgcggttaaa ggcaatgatg ccgccgaatg cggaggttgg gtcggttttg tacgcgcgat
    29701 cgtaagcatc aagaatggaa ttgccgatag ctacaccgca agggttggcg tgcttcacaa
    29761 tcacacatgc cggctcggcg aactctttca cgcactccag cgccgcatcg gtatcggcga
    29821 tgttgttata agagagggct ttaccctgaa cctgggttgc ggtagcaacg gaggcttctt
    29881 tcacattctc ttctatatag aaggcagcct gctggtggct gttctcgccg taacgcatat
    29941 cctgcttctt aatgaagttc aggttcagcg tgcgtgggaa gcgaccagcg gcttctttgc
    30001 tttcaccgtg gtacgccgga accatgctgc cgaagtagtt ggcaatcatg ctgtcgtagg
    30061 cggcagtgtg ttcgaaggct ttgatggcga ggtcgaaacg ggttgcaagc gtcagcgatc
    30121 cttcgttgtc atccatctct ttaataatgg cgtcgtagtc gctgctcttc accacgattg
    30181 cgacatcttt atggttctta gcggcggagc gcaccatggt cgggccgccg atatcgatgt
    30241 tctcaaccgc atcttccagc gagcaacctt cacgggccac ggtctgggcg aacggataca
    30301 ggttaacaac caccatatcg ataggctgga tctgatgttc ttccataatg gcatcgtcct
    30361 ggccgcgacg gcccagaatg ccaccatgta ctttcggatg cagggtcttc acgcgtccat
    30421 ccatcatctc cgggaaaccg gtgtaatcgg aaacttcggt taccggcaga cctttttctg
    30481 ctaacagacg ggcagtgccc cctgtagaca gcagctccac accgcgtgcg gaaagtgcct
    30541 gggcgaattc gacgataccg gctttgtcag aaacactgag cagagcgcgg cggactggac
    30601 gacgttgttg catggtaaat cccctggatt tgactattac agagagcgtt agctgaattt
    30661 ttcgcgaaaa actcagctaa cgcccctaac ggggcatcct tatttttcgc ccgcattgta
    30721 acgaaaacgt ttgcgcaacg ctcgcgaatt tttctctttc aatggtgatc acaattttga
    30781 cagtggttac cgtgggaaaa atacagaaat tacattgatg attgtggata actctgtgcg
    30841 taaaaaggta taaagcgggg ttttgctggg gaatgcagca gtcagtcatt tttctgcaat
    30901 ttttctattg cggcctgcgg agaactccct ataatgcgcc tccatcgaca cggcggatgt
    30961 gaatcacttc acacaaacag ccggttcggt tgaagagaaa aatcctgaaa ttcagggttg
    31021 actctgaaag aggaaagcgt aatatacgcc acctcgc
//
LOCUS       DAPGUL010000050        29860 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.050, whole genome shotgun sequence.
ACCESSION   DAPGUL010000050 DAPGUL010000000
VERSION     DAPGUL010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 29860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29860
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.050"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            138..680
                     /gene="ecpR"
                     /locus_tag="RHX21_002409"
                     /gene_synonym="matA"
     CDS             138..680
                     /gene="ecpR"
                     /locus_tag="RHX21_002409"
                     /gene_synonym="matA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECP biosynthesis operon DNA-binding
                     transcriptional regulator EcpR"
                     /protein_id="HDV1987579.1"
                     /translation="MECQNRSDKYIWSPHDAYFYKGLSELIVDIDRLIYLSLEKIRKD
                     FVFINLNTDSLSEFINRDNEWLSAVKGKQVVLIAARKSEALANYWYYNSNIRGVVYAG
                     LSRDIRKELAYVINGRFLRKDIKKDKITDREMEIIRMTAQGMQPKSIARIENCSVKTV
                     YTHRRNAEAKLYSKIYKLVQ"
     gene            755..1342
                     /gene="ecpA"
                     /locus_tag="RHX21_002410"
                     /gene_synonym="matB"
     CDS             755..1342
                     /gene="ecpA"
                     /locus_tag="RHX21_002410"
                     /gene_synonym="matB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="common pilus major fimbrillin subunit EcpA"
                     /protein_id="HDV1987580.1"
                     /translation="MKKKVLAIALVTVFTGMGVAQAADVTAQAVATWSATAKKDTTSK
                     LVVTPLGSLAFQYAEGIKGFNSQKGLFDVAIEGDSTATAFKLTSRLITNTLTQLDTSG
                     STLNVGVDYNGAAVEKTGDTVMIDTANGVLGGNLSPLANGYNASNRTTAQDGFTFTII
                     SGTTNGTTAVTDYSTLPEGIWSGDVSVQFDATWTS"
     gene            1400..2068
                     /gene="ecpB"
                     /locus_tag="RHX21_002411"
                     /gene_synonym="yagY"
     CDS             1400..2068
                     /gene="ecpB"
                     /locus_tag="RHX21_002411"
                     /gene_synonym="yagY"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone EcpB"
                     /protein_id="HDV1987581.1"
                     /translation="MKKHLLPLALLFSGISPAQALDVGDISSFMNSDSSTLSKTIKNS
                     TDSGRLINIRLERLSSPLDDGQVISMDKPDELLLTPASLLLPAQASEVIRFFYKGPAD
                     EKERYYRIVWFDQALSDAQRDNANRSAVATASARIGTILVVAPRQANYHFQYANGSLT
                     NTGNATLRILAYGPCLKAANGKECKENYYLMPGKSRRFTRVDTADNKGRVALWQGDKF
                     IPVK"
     gene            2094..4619
                     /gene="ecpC"
                     /locus_tag="RHX21_002412"
                     /gene_synonym="yagX"
     CDS             2094..4619
                     /gene="ecpC"
                     /locus_tag="RHX21_002412"
                     /gene_synonym="yagX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial usher EcpC"
                     /protein_id="HDV1987582.1"
                     /translation="MPLRRFSPGLKAQFAFGMVFLFVQPDASAADISAQQIGGVIIPQ
                     AFSQALQDGMSVPLYIHLAGSQGRQDDQRIGSAFIWLDDGQLRIRKIQLEESEDNASV
                     SEQTRQQLMALANAPFNEALTIPLTDNAQLDLSLRQLLLQLVVKREALGTVLRSRSED
                     IGQSSVNTLSSNLSYNLGVYNNQLRNGGSNTSSYLSLNNVTALREHHVVLDGSLYGIG
                     SGQQDSELYKAMYERDFAGHRFAGGMLDTWNLQSLGPMTAISAGKIYGLSWGNQASST
                     IFDSSQSATPVIAFLPAAGEVHLTRDGRLLSVQNFTMGNHEVDTRGLPYGIYDVEVEV
                     IVNGRVISKRPQRVNKLFSRGRGVGAPLAWQVWGGSFHMDRWSENGKKTRPAKESWLA
                     GASTSGSLSTLSWAATGYGYDNQAVGETRLTLPLGGAINVNLQNMLASDSSWSSIGSI
                     SATLPGGFSSLWVNQEKTHIGNQLRRSDADNRAIGGTLNLNSLWSKLGTFSISYNDDR
                     RYNSHYYTADYYQNVYSGTFGSLGLRAGIQRYNNGDSNANTGKYIALDLSLPLGNWFS
                     AGMTHQNGYTMANLSARKQFDEGTIRTVGANLSRAISGDTGDDKTLSGGAYAQFDARY
                     ASGTLNVNSAADGYINTNLTANGSVGWQGKNIAASGRTDGNAGVIFNTGLEDDGQISA
                     KINGRIFPLNGKRNYLPLSPYGRYEVELQNSKNSLDSYDIVSGRKSHLTLYPGNVAVI
                     EPEVKQMVTVSGRIRAEDGTLLANARINNHIGRTRTDENGEFVMDVDKKYPTIDFRYS
                     GNKTCEVALELNQARGAVWVGDVVCSGLSSWAAVTQTGEENES"
     gene            4609..6252
                     /gene="ecpD"
                     /locus_tag="RHX21_002413"
     CDS             4609..6252
                     /gene="ecpD"
                     /locus_tag="RHX21_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial adhesin EcpD"
                     /protein_id="HDV1987583.1"
                     /translation="MRVNLLITMIIFALIWPVTELRAAVSKTTWADAPAREFVFVENN
                     SDDNFFVTPGGALDPRLTGANRWTGLKYTGSGTIYQQSLGYIDNGYNTGLYTNWKFDM
                     WLENSPVSSPLTGLRCINWYAGCNMTTSLILPQTTDASGFYGATVTSGGAKWMHGMLS
                     DAFYQYLQQMPVGSSFTMTINACQTSVNYDASSGARCKDQATGNWYVRNVTHTKAANL
                     RLINTHSLAEVFINSDGVPTLGEGNADCRTQTIGSLSGLSCKMVNYTLQTNGLSNTSI
                     HIFPAIANSSLASAVGAYDMQFSLNGSSWKPVSNTAYYYTFNEMKSADSIYVFFSSNF
                     FKQMVNLGISDINTKDLFNFRFQNTTSPESGWYEFSTSNTLIIKPRDFSISIISDEYT
                     QTPSREGYVGSGESALDFGYIVTTSGKTAADEVLIKVTGPAQVIGGRSYCVFSSDDGK
                     AKVPFPATLSFITRNGATKTYDAGCDDSWRDMTDALWLTTPWTDISGEVGQMDKTTVK
                     FSIPMDNAISLRTVDDNGWFGEVSASGEIHVQATWRNIN"
     gene            6221..6931
                     /gene="ecpE"
                     /locus_tag="RHX21_002414"
     CDS             6221..6931
                     /gene="ecpE"
                     /locus_tag="RHX21_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414823.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone EcpE"
                     /protein_id="HDV1987584.1"
                     /translation="MFRRRGVTLTKALLTAVCMLAAPLTQAISVGNLTFSLPSETDFV
                     SKRVVNNNKSARIYRIAISAIDSPGSSELRTRPVDGELLFAPRQLALQAGESEYFKFY
                     YHGPRDNRERYYRVSFREVPTRNQTRRSPTGGEVSTEPVVVMDTILVVRPRQVQFKWS
                     FDKVTGTVSNTGNTWFKLLIKPGCDSTEEEGDAWYLRPGDVVHQPELRQPGNHYLVYN
                     DKFIKISDSCPAKPPSAD"
     gene            7244..7573
                     /locus_tag="RHX21_002415"
     CDS             7244..7573
                     /locus_tag="RHX21_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HDV1987585.1"
                     /translation="MSNLNPCMTCGACCAFFRVSFYWAEADDAGGTIPARLTEQISPF
                     HRCMSGTNQKNPRCIALAGTPGKNACCTIYKNRSSTCREFAMSGENGVVNEACNRARA
                     KYGLTPL"
     gene            complement(7821..8435)
                     /locus_tag="RHX21_002416"
     CDS             complement(7821..8435)
                     /locus_tag="RHX21_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YagU family protein"
                     /protein_id="HDV1987586.1"
                     /translation="MNIFEQTPPNRRRYGLAAFIGLIAGVVSAFVKWGAEVPLPPRSP
                     VDMFNAACGPESLIRAAGQIDCSRNFLNPPYIFLRDWLGLTDPNAAVYTFAGHVFNWV
                     GVTHIIFSIVFAVGYCVVAEVFPKIKLWQGLLAGALAQLFVHMISFPLMGLTPPLFDL
                     PWYENVSEIFGHLVWFWSIEIIRRDLRNRITHEPDPEIPLGSNR"
     gene            8853..9542
                     /gene="paoA"
                     /locus_tag="RHX21_002417"
     CDS             8853..9542
                     /gene="paoA"
                     /locus_tag="RHX21_002417"
                     /EC_number="1.2.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase iron-sulfur subunit"
                     /protein_id="HDV1987587.1"
                     /translation="MSNQGEYPEDNRVGKHEPHDLSLTRRDLIKVSAATAATAVVYPH
                     STLAASVPAATPAPEIMPLTLKVNGKTEQLEVDTRTTLLDALRENLHLIGTKKGCDHG
                     QCGACTVLVNGRRLNACLTLAVMHQGAEITTIEGLGSPDNLHPMQAAFIKHDGFQCGY
                     CTSGQICSSVAVLKEIQDGIPSHVTVDLVSAPETTADEIRERMSGNICRCGAYANILA
                     AIEDAAGEIKS"
     gene            9539..10495
                     /gene="paoB"
                     /locus_tag="RHX21_002418"
     CDS             9539..10495
                     /gene="paoB"
                     /locus_tag="RHX21_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde oxidoreductase FAD-binding subunit
                     PaoB"
                     /protein_id="HDV1987588.1"
                     /translation="MKAFTYERVNTPAEAALSAQRVPGAKFIAGGTNLLDLMKLEIET
                     PTHLIDVNGLGLDKIEVTDAGGLRIGALVRNTDLAAHERVRRDYAVLSRALLAGASGQ
                     LRNQATTAGNLLQRTRCPYFYDTNQPCNKRLPGSGCAALEGFSRQHAVVGVSEACIAT
                     HPSDMAVAMRLLDAVVETITPEGKTRSITLADFYHPPGKTPHIETALLPGELIVAVTL
                     PPPLGGKHIYRKVRDRASYAFALVSVAAIIQPDGSGRVALGGVAHKPWRIEAADAQLS
                     QGAQAVYDTLFASAHPTAENTFKLLLAKRTLASVLAEARAQA"
     gene            10492..12690
                     /gene="paoC"
                     /locus_tag="RHX21_002419"
     CDS             10492..12690
                     /gene="paoC"
                     /locus_tag="RHX21_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde oxidoreductase molybdenum-binding
                     subunit PaoC"
                     /protein_id="HDV1987589.1"
                     /translation="MKFDKPAGENPIDQLKVVGRPHDRIDGPLKTTGTARYAYEWHEE
                     APNAAYGYIVGSAIAKGRLTALDTDAAQKAPGVLAVITASNAGALGKGDKNTARLLGG
                     PTIEHYHQAIALVVAETFEQARAAASLVQAHYRRNKGAYSLADEKQAVNQPPEDTPDK
                     NVGDFDGAFTSAAVKIDATYTTPDQSHMAMEPHASMAVWDGNKLTLWTSNQMIDWCRT
                     DLAKTLKVPVENVRIISPYIGGGFGGKLFLRSDALLAALAARAVKRPVKVMLPRPSIP
                     NNTTHRPATLQHLRIGADQSGKITAISHESWSGNLPGGTPETAVQQSELLYAGANRHT
                     GLRLATLDLPEGNAMRAPGEAPGLMALEIAIDELAEKAGIDPVEFRILNDTQVDPADP
                     TRCFSRRQLIECLRTGADKFGWKQRNATPGQVRDGEWLVGHGVAAGFRNNLLEKSGAR
                     VHLEQNGTVTVETDMTDIGTGSYTILAQTAAEMLGVPLEQVAVHLGDSSFPVSAGSGG
                     QWGANTSTSGVYAACMKLREMIASAVGFDPEQSQFADGKITNGTRSATLHEATAGGRL
                     TAEESIEFGTLSKEYQQSTFAGHFVEVGVHSATGEVRVRRMLAVCAAGRILNPKTARS
                     QVIGAMTMGMGAALMEELAVDDRLGYFVNHDMAGYEVPVHADIPKQEVIFLDDTDPIS
                     SPMKAKGVGELGLCGVSAAIANAVYNATGIRVRDYPITLDKLLDKLPDVV"
     gene            12700..13656
                     /gene="paoD"
                     /locus_tag="RHX21_002420"
     CDS             12700..13656
                     /gene="paoD"
                     /locus_tag="RHX21_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor insertion chaperone PaoD"
                     /protein_id="HDV1987590.1"
                     /translation="MSYPLFDKDEHWHKPEQAFLTDDHRTILRFAVEALMSGKGAVLV
                     TLVEIRGGAARPLGAQMVVREDGRYCGFVSGGCVEAAAAFEALEMMGSGRDREIRYGE
                     GSPWFDIVLPCGGGITLTLHKLRSAQPLLAVLNRLEQRKPAGLRYDPQAQSLVCLPTQ
                     TRTGWNLNGFEVGFRPCVRLMIYGRSLEAQATASLAAATGYDSHIFDLFPASASAQID
                     TDTAVILLCHDLNRELPVLQAAREAKPFYLGALGSHRTHTLRLQKLHELGWSREETAQ
                     IRAPVGIFPKARDAHTLALSVLAEIASVRLHQEEDSCLPPSS"
     gene            13707..14045
                     /locus_tag="RHX21_002421"
                     /pseudo
     CDS             13707..14045
                     /locus_tag="RHX21_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308332.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            complement(14172..14247)
                     /locus_tag="RHX21_002422"
     tRNA            complement(14172..14247)
                     /locus_tag="RHX21_002422"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14212..14214),aa:Thr,seq:cgt)
     gene            complement(14362..15615)
                     /gene="proA"
                     /locus_tag="RHX21_002423"
     CDS             complement(14362..15615)
                     /gene="proA"
                     /locus_tag="RHX21_002423"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HDV1987591.1"
                     /translation="MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSEIILN
                     ANAQDVADARANGLGEAMLDRLALTPARLKGIADDVRQVCNLADPVGQVIDGSVLDSG
                     LRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQ
                     DALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVI
                     TGGIGVCHIYVDESVEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQ
                     MAESGVTLHADAAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIR
                     EHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLH
                     ARGPMGLEALTTYKWIGIGDYTIRA"
     gene            complement(15627..16730)
                     /gene="proB"
                     /locus_tag="RHX21_002424"
     CDS             complement(15627..16730)
                     /gene="proB"
                     /locus_tag="RHX21_002424"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HDV1987592.1"
                     /translation="MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHR
                     IVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQML
                     LTRADMEDRERFLNARDTLRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILA
                     GADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKL
                     QAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAG
                     EITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDA
                     LRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR"
     gene            17018..18073
                     /gene="phoE"
                     /locus_tag="RHX21_002425"
     CDS             17018..18073
                     /gene="phoE"
                     /locus_tag="RHX21_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoporin PhoE"
                     /protein_id="HDV1987593.1"
                     /translation="MKKSTLALVVMGIVASASVQAAEIYNKDGNKLDVYGKVKAMHYM
                     SDNDSKDGDQSYIRFGFKGETQINDQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGL
                     KYKDLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFF
                     GVIDGLNLTLQYQGKNENRDVKKQNGDGFGTSLTYDFGGSDFAISGAYTNSDRTNEQN
                     LQSRGTGKRAEAWATGLKYDANNIYLATFYSETRKMTPITGGFANKTQNFEAVAQYQF
                     DFGLRPSLGYVLSKGKDIEGIGGEDLVNYIDVGATYYFNKNMSAFVDYKINQLDSDNK
                     LNINNDDIVAIGMTYQF"
     gene            complement(18112..18513)
                     /gene="crl"
                     /locus_tag="RHX21_002426"
     CDS             complement(18112..18513)
                     /gene="crl"
                     /locus_tag="RHX21_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-binding protein Crl"
                     /protein_id="HDV1987594.1"
                     /translation="MTLPSGHPKSRLIKKFTALGPYIREGKCEDNRFFFDCLAVCVNV
                     KPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWKSVPVKDTEVVERLEHTLRE
                     FHEKLRELLTTLNLKLEPADDFRDEPVKLTA"
     gene            complement(18571..19815)
                     /gene="frsA"
                     /locus_tag="RHX21_002427"
     CDS             complement(18571..19815)
                     /gene="frsA"
                     /locus_tag="RHX21_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase FrsA"
                     /protein_id="HDV1987595.1"
                     /translation="MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTI
                     PHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWA
                     TQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEA
                     AQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYF
                     APRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGA
                     NVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEA
                     LRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFN
                     PVYRNFDKGLQEITGWIEKRLC"
     gene            complement(19907..20365)
                     /gene="gpt"
                     /locus_tag="RHX21_002428"
     CDS             complement(19907..20365)
                     /gene="gpt"
                     /locus_tag="RHX21_002428"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HDV1987596.1"
                     /translation="MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR"
     gene            20626..22083
                     /gene="pepD"
                     /locus_tag="RHX21_002429"
     CDS             20626..22083
                     /gene="pepD"
                     /locus_tag="RHX21_002429"
                     /EC_number="3.4.13.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosol nonspecific dipeptidase"
                     /protein_id="HDV1987597.1"
                     /translation="MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKG
                     FHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDG
                     EWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQSNWL
                     QADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFKLTLKGLKGGHSGG
                     EIHVGLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDVL
                     KSLVNTYQEILKNELAEKEKNLALLLDSVANDKAALIAKSRDTFIRLLNATPNGVIRN
                     SDVAKGVVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEA
                     KGAYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIG
                     PTITGPHSPDEQVHIESVGHYWTLLTELLKEIPAK"
     gene            complement(22140..22754)
                     /locus_tag="RHX21_002430"
     CDS             complement(22140..22754)
                     /locus_tag="RHX21_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor H"
                     /protein_id="HDV1987598.1"
                     /translation="MILLQLSSAQGPEECCLAVKKALDRLIKEAARQDVAVTVLETET
                     GRYSDTLRSALVSLDGDNAWALSESWCGTIQWICPSPYRPHHGRKNWFLGIGRFTADE
                     QEQSDAIRYETLRSSGPGGQHVNKTDSAVRATHLASGISVKVQSERSQHANKRLARLL
                     IAWKLEQQQQENSAVLKSQRRMFHHQIERGNPRRTFTGMAFIEG"
     gene            complement(22751..23890)
                     /locus_tag="RHX21_002431"
     CDS             complement(22751..23890)
                     /locus_tag="RHX21_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HDV1987599.1"
                     /translation="MGNYIRPLSDAVFTIASDDLWIESLAIQQLHTTANLPNMQRVVG
                     MPDLHPGRGYPIGAAFFSVGRFYPALVGNDIGCGMALWQTDILTRKYNADKFEKRLSD
                     LDDVAEESWLEENLPSAFAQHPWRSSLGSIGGGNHFAELQQVDQIINAELFALAGLDA
                     QHLQLLVHSGSRGVGQSILQRHIASFSHHGLPQGSDDALRYIAEHDDALAFACINRQM
                     IALRIMQQVKATGSPVLDVAHNFVSACQIGDQQGWLHRKGATPDDNGLVIIPGSRGDY
                     SWIVQPVANEKTLHSLAHGAGRKWGRTECKGRLAAKYTATQLSRTELGSRVICRDKQL
                     IFEEAPQAYKSAESVVQCLVQAGLIIPVARLRPVLTLKNSGGKKG"
     gene            complement(24136..24588)
                     /locus_tag="RHX21_002432"
     CDS             complement(24136..24588)
                     /locus_tag="RHX21_002432"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDV1987600.1"
                     /translation="MNNIQIRDYQPGDFQQLCAIFIRAVTMTASQHYSPQQIAAWAQI
                     DESRWKEKLAKSQVRVAVINAKLVGFITCVEHYIDMLFVDPEYTRRGVASALLKPLIK
                     SESELTVDASITAKPFFERYGFQTVKQQRVECRGEWFINFYMRYKQQH"
     gene            complement(24585..25640)
                     /gene="dinB"
                     /locus_tag="RHX21_002433"
     CDS             complement(24585..25640)
                     /gene="dinB"
                     /locus_tag="RHX21_002433"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HDV1987601.1"
                     /translation="MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTA
                     NYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSL
                     DEAYLDVTDSVHCHGSATLIAQEIRQTIFSELQLTASAGVAPVKFLAKIASDMNKPNG
                     QFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVMLLKRFGKF
                     GRILWERSQGIDERDVNSERLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAK
                     VKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATARKTWDERRGGRGVRLVGL
                     HVTLLDPQMERQLVLGL"
     gene            complement(25711..26496)
                     /gene="lafU"
                     /locus_tag="RHX21_002434"
     CDS             complement(25711..26496)
                     /gene="lafU"
                     /locus_tag="RHX21_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706230.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative lateral flagellar export/assembly
                     protein LafU"
                     /protein_id="HDV1987602.1"
                     /translation="MTTIKLIVNSVSKSERESIIAALHGQSIFNGGGLSPLNKISPSH
                     PPKPATVAVPEETEKKARDVNEKTVLLKKKSATELGELATSINTIARDAHMEANLEME
                     IVPQGLRVLIKDDQNRNMFERGSAQIMPFFKRLLVELAPVFDSLDNKIIITGHTDAMA
                     YKNNIYNNWNLSGDRALSARRVLEEAGMPEDKVMQVSAMADQMLLDSKNPQSAGNRRI
                     EIMVLTKSASDTLYQYFGQHGDKVVQPLVQKLDKQQVLSQRTR"
     gene            26468..28180
                     /locus_tag="RHX21_002435"
                     /pseudo
     CDS             26468..28180
                     /locus_tag="RHX21_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
     gene            28285..28563
                     /locus_tag="RHX21_002436"
     CDS             28285..28563
                     /locus_tag="RHX21_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HDV1987603.1"
                     /translation="MIKVSALGSRHRKTFDDVMTEPPKSGIKWDDVVALIKAVGGTIK
                     NNNGSRRKFQIGTTKFSTHEPHPKNVMDKGAVAGLKEWFVNCVGGDYE"
     gene            28556..28912
                     /locus_tag="RHX21_002437"
     CDS             28556..28912
                     /locus_tag="RHX21_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HDV1987604.1"
                     /translation="MNKASNIITIKGQPAAVTFEADINAFRGKFLNVNGYCDFVATSI
                     EALYREGESALDEWMADCEEDGIAPFREEEEQKRLTLRVPHHIDSRLTIVARQHSISK
                     NQLIVDVLEREFSAHM"
     gene            complement(28969..29742)
                     /locus_tag="RHX21_002438"
     CDS             complement(28969..29742)
                     /locus_tag="RHX21_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308281.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDV1987605.1"
                     /translation="MHDQPLLSMSLPSIPSFVLSGLLLLCLPFSSFASATTSHITFSY
                     AARQRMQNRARLLKQYQTHLKKQASYIVEGNAESRRALRQHNREQIKQHPEWFPAPLK
                     ASDRRWQALAENNHFLSSDHLHNITEVAIHRLEQQLGKPYVWGGTRPDQGFDCSGLVF
                     YAYNKILEAKLPRTANEMYHYHRATIVANNDLRRGDLLFFHIHSREIADHMGVYLGDG
                     QFIESPRTGETIRVSRLAEPFWQDHFLGARRILTEETIL"
BASE COUNT         7351 a         7889 c         7733 g         6887 t
ORIGIN      
        1 cctttattga tatgtactac gtatcttatt tacttccggt ttactaagga aactgaatgc
       61 acctgtaaaa attacaggtt tggaaagtag tgacatggca aagtgattac agcagggact
      121 atgaggttaa aaaccatatg gaatgtcaaa accgttctga taaatacatc tggtctcccc
      181 atgacgccta cttctataaa ggactatctg aactgattgt ggatatcgac agattaattt
      241 atctatcgtt ggagaaaatt agaaaagatt tcgtgtttat caatctcaat acggattctt
      301 tatctgaatt tataaaccgt gataatgaat ggttatccgc ggtaaagggg aaacaggtcg
      361 tattgattgc ggccagaaag tcagaagcct tagcaaatta ttggtattac aatagcaata
      421 ttaggggcgt ggtatacgct ggactgagtc gtgatattag aaaagaactg gcctatgtga
      481 ttaatggcag gttcctgaga aaagatatta agaaagataa aatcacggac cgggaaatgg
      541 aaattatccg catgacggcc cagggaatgc aacctaaatc gattgccaga attgaaaatt
      601 gtagtgtgaa gacagtgtat acccatcggc gtaatgctga ggccaagctg tactcaaaaa
      661 tatataagtt ggttcagtaa actccaggca agttagtttt aaaaaatgac tcactgggac
      721 atcacgtcct caattcaact cgggaagaaa tgcaatgaaa aaaaaggttc tggcaatagc
      781 tctggtaacg gtgtttaccg gcatgggtgt ggcgcaggct gctgacgtaa cagctcaggc
      841 tgtagcgacc tggtcggcaa cagccaaaaa agacaccacc agtaagctgg ttgtgacgcc
      901 actcggtagc ctggcgttcc agtatgccga aggcattaaa ggttttaact cacagaaagg
      961 tctatttgac gtggctatcg agggtgactc aacggctacc gcctttaaac tgacctcacg
     1021 tcttatcacc aacacattaa cccagttgga tacctcaggt tccacactga atgtgggcgt
     1081 ggattataac ggcgcggcag tcgaaaaaac tggcgatacc gtgatgatcg ataccgccaa
     1141 cggcgtactg ggcggcaacc ttagcccgct ggctaacggt tacaatgcca gcaatcgtac
     1201 caccgcacag gatggtttca ccttcaccat catcagcggc accaccaatg gtaccaccgc
     1261 agtaaccgat tacagcactc taccggaagg catctggagc ggcgacgtta gcgtacagtt
     1321 cgacgcgacc tggaccagtt aatctctctg atgtaccagc aggggtagcc cccctgcttt
     1381 attcctggac ggaattgtta tgaaaaagca ccttctgcct ctcgctctgc tgttttccgg
     1441 aatatctccg gcccaggcgc tggatgtcgg cgatatatca tcgtttatga acagtgacag
     1501 cagcacgctg agcaaaacga tcaaaaacag taccgacagt ggtcgcctta tcaatatccg
     1561 tctcgaacgg ctctcttcac cgcttgacga cgggcaggtt atctcaatgg acaagccgga
     1621 tgagttgcta ctcactcccg ccagcttgct gctacccgcc caagccagcg aagtgatccg
     1681 cttcttctat aagggacccg cagatgaaaa agagcgctac taccgcattg tctggtttga
     1741 tcaggccctc agtgatgcgc agcgcgataa tgccaaccgc agcgctgtgg ccactgcttc
     1801 cgcccgcatc ggcaccattc tggtcgtcgc cccccgccag gcgaactacc actttcagta
     1861 cgccaacggc tccctgacaa atacaggaaa tgcgacgctg cggatcctcg cctacggccc
     1921 ttgcctgaaa gccgccaacg gtaaggagtg taaagagaat tactacctga tgccgggcaa
     1981 gtcgcgtcgt tttacccgcg tggacacggc ggataacaaa ggacgggttg cactttggca
     2041 gggtgataag ttcattcccg tgaaatagat agctgtgcag atggataacg acaatgcctt
     2101 tacgacggtt ctccccagga ctgaaagccc agtttgcctt cggcatggtc tttttgttcg
     2161 ttcagcccga tgccagcgct gctgacataa gtgcgcagca aataggtggg gtgattattc
     2221 cgcaggcctt cagtcaggcg cttcaggacg gcatgagcgt cccgctctat attcatctcg
     2281 ccggtagcca gggtcgccag gacgatcagc gaatcggcag cgcttttatc tggctggatg
     2341 atggacagct acgcatccgg aaaatacagc tggaagagag tgaagataac gccagtgtca
     2401 gcgaacaaac tcgacagcag ctgatggctc tggccaacgc cccgttcaat gaggccctta
     2461 ccatccccct gactgacaac gcgcagctgg atctcagctt gcgccaactg ctgctgcagc
     2521 tggtggtcaa gcgcgaagcg ctgggcaccg tactacgctc acgtagcgaa gacatcgggc
     2581 agtccagtgt taacaccctc agcagtaatc tgagctataa cttgggcgtc tataacaacc
     2641 agttgcgtaa cggcgggagc aacacatcca gctatctgtc gctgaataac gttactgcgc
     2701 tgcgcgaaca ccatgtggtg ctcgacggct cgctgtacgg gatcggtagc ggtcaacagg
     2761 acagtgaatt atataaagcg atgtatgaac gcgattttgc cggtcaccga tttgccggtg
     2821 gaatgctcga cacctggaac ttgcagtcct tagggccgat gaccgccatt tcagcaggga
     2881 agatttacgg cctttcctgg ggaaaccagg ccagctccac catcttcgac agcagccagt
     2941 cagccacgcc agtgatcgcc tttttaccgg cggcgggcga agtacatctc acccgtgatg
     3001 ggcggctact aagcgttcag aacttcacta tgggcaatca tgaagtggat acccggggtc
     3061 taccgtacgg gatttacgat gtggaagttg aggtgatcgt taacggtcgc gtgatcagca
     3121 aacgccccca gcgggtcaat aagctgttta gccgggggcg cggcgtcggt gcaccactgg
     3181 cgtggcaggt atggggcggt agctttcata tggatcgctg gtcggaaaac gggaaaaaga
     3241 cgcgaccagc taaagagagt tggctagcag gtgcctcgac ctccggctca ttgagtacgc
     3301 ttagctgggc ggcaacggga tatggatacg ataatcaggc ggtgggtgaa acccgtctga
     3361 cgctgccgct tgggggggcg atcaacgtta acctgcaaaa tatgctggcc agtgacagct
     3421 catggagcag catcggcagc atcagcgcca ctctaccggg aggctttagt tcgctgtggg
     3481 ttaaccagga aaaaacccac attggcaatc aattgcgacg tagcgatgcc gacaaccgtg
     3541 caatcggcgg cacactcaac ctgaactcac tgtggtcgaa gctgggcaca ttcagcatca
     3601 gctacaatga tgaccgccgt tacaacagcc attattacac ggcagattac tatcaaaatg
     3661 tctacagcgg tacctttggt tcgcttggcc tgcgggccgg tattcagcgc tataacaacg
     3721 gcgacagcaa cgccaataca gggaaatata tcgctctcga tctctcgtta ccactgggca
     3781 actggtttag cgcagggatg acccatcaaa acggctacac catggcaaac ctgtcagcac
     3841 gcaaacagtt tgatgaagga accattcgca ctgttggtgc caatctgtca cgtgccatct
     3901 ccggcgatac cggtgatgac aaaaccctca gcggtggggc gtatgcacag ttcgacgctc
     3961 gttacgccag cggaacgctg aacgtcaata gcgcggcgga cggctacatc aataccaact
     4021 tgaccgccaa tggcagcgtc ggctggcagg gtaaaaacat cgctgccagc gggcggactg
     4081 atggcaacgc tggggtgata ttcaacaccg ggctggagga cgacggtcag atcagcgcca
     4141 aaatcaacgg gcggattttc ccgcttaacg gcaagcgtaa ctatctcccg ctctctccct
     4201 atggaagata tgaggtggag ttacagaaca gcaaaaactc actcgacagc tacgatatcg
     4261 tcagcggccg caaaagccat ctgactctct atccaggcaa tgtcgctgtc attgagccag
     4321 aggtgaagca gatggttacc gtctccggtc gtatccgtgc ggaagacggc acactgctgg
     4381 ctaacgcacg gattaacaac catatcggcc gaacccgaac cgatgaaaac ggcgagtttg
     4441 tcatggacgt ggataagaaa tatcccacta tcgattttcg ctacagtggc aataaaacct
     4501 gcgaagtggc actggaactc aaccaggcgc gcggtgccgt ctgggtcggt gatgtggtct
     4561 gcagcggcct ctcatcgtgg gcggcggtga cgcagacagg agaagagaat gagagttaac
     4621 ctactaataa cgatgataat tttcgcgcta atctggccag taactgagct cagagcggca
     4681 gtgagcaaaa caacctgggc ggatgcaccg gcacgcgagt ttgtgtttgt cgaaaacaac
     4741 tcagacgaca actttttcgt cactcctggc ggggcgctgg atccgcgcct gaccggtgcc
     4801 aaccgctgga ccggtttaaa atacactggt tcaggaacca tctatcagca aagcctcggc
     4861 tacattgata acggttacaa caccggcctt tataccaact ggaagtttga tatgtggctg
     4921 gaaaattcac cagtttcatc tcctttaact ggcttgcgct gcatcaactg gtacgctggg
     4981 tgtaatatga ccaccagtct tatcctgccg caaaccaccg acgccagtgg attttatggc
     5041 gcgacggtga ccagcggcgg cgcgaagtgg atgcacggca tgttgtcaga cgcgttttac
     5101 cagtatctgc aacaaatgcc cgtcggcagc agctttacaa tgaccatcaa tgcctgccag
     5161 acctctgtga actatgacgc cagcagcggc gcacgctgta aggatcaggc caccggcaac
     5221 tggtatgttc gcaacgtcac ccatacgaaa gcagcaaatc tgcggttaat aaatacccac
     5281 tcgctggcgg aggtatttat caacagcgac ggagtaccga ctctgggcga agggaacgcc
     5341 gactgccgga cacagaccat cggcagcctt tcaggattaa gttgtaagat ggtcaactat
     5401 accctgcaaa caaacggact cagcaacacc tcaatccata tattcccggc gatcgccaac
     5461 tcgtcgttag cctcggccgt cggggcgtac gatatgcagt tcagtctgaa tggcagttca
     5521 tggaaaccgg tgagcaatac cgcctattac tacaccttca acgagatgaa gagcgcagac
     5581 tcgatctatg ttttcttctc gagcaacttc tttaagcaga tggtgaacct cgggatcagc
     5641 gatatcaaca ccaaagatct attcaacttt cgctttcaga acaccacatc accggagtct
     5701 ggctggtatg aattttctac ctccaacacg ctgattatca aaccccgtga tttcagcatc
     5761 agtattatct ccgatgaata tactcagaca ccgtcgcggg agggatatgt tggcagcggc
     5821 gagtcggcac tcgatttcgg ctatatcgta accaccagcg gtaaaacagc tgccgacgaa
     5881 gtgctgatca aggtgaccgg acccgcgcag gtgattggcg ggcgctccta ttgtgtcttc
     5941 agctccgatg acggtaaggc gaaagtaccg ttcccggcga cactttcctt tattacccgc
     6001 aacggagcta caaaaaccta cgatgccggg tgcgatgata gctggcggga tatgaccgat
     6061 gcgctgtggt tgaccacacc gtggactgat atctctggcg aagtggggca gatggataag
     6121 accacagtca aattttcgat tccaatggat aacgccattt cgctgcgtac ggtagatgat
     6181 aacggctggt ttggcgaagt cagcgcttca ggagagattc atgttcaggc gacgtggcgt
     6241 aacattaact aaagccctgc tgacagcggt ctgtatgctg gcggcacctt tgacacaggc
     6301 gatttcggtc ggcaatctga cattttcgct gccgtccgag actgactttg tcagcaaacg
     6361 tgtagtgaat aacaacaaaa gcgcacggat ataccgtatt gccatcagtg ctattgatag
     6421 cccgggcagc agtgaattgc gcacccgacc ggtggatggt gaactgcttt tcgccccccg
     6481 ccaactggcg ttgcaggctg gtgagagcga gtattttaaa ttttactatc atggtccacg
     6541 ggataaccgc gagcgctact accgggtctc atttcgcgaa gtccccactc gtaaccagac
     6601 aagacgtagc ccaaccggcg gcgaggtcag cacggagccg gtggtggtga tggataccat
     6661 tctggtagta cgaccacgtc aggttcagtt taaatggtcc ttcgacaagg tgacaggaac
     6721 ggtaagtaac actggcaaca catggtttaa gctactgatt aagccaggat gtgattcgac
     6781 cgaagaggaa ggcgatgcct ggtatctacg tccgggagac gtggttcatc agcctgagtt
     6841 acgtcagccg gggaatcatt atctggtcta taacgacaaa ttcattaaga ttagcgattc
     6901 ctgtccggct aagccccctt cggcggacta agacttatcc atcggtcgag ggaagaattc
     6961 cacctcagag ccccaaaaat cgtttaaatg atgtggaagc gatcgtcaat atcacctgta
     7021 acgatgggct ttctcatatg cacaccatag tgttcaggag acacggaaag gtatcaggca
     7081 gcctgctaac gagtggttta atcacgaatt agtacgtaaa atcggtaacg gctggaaatc
     7141 attcaatact cacactatcg aaagttcccc agccaaccgc ggtacgttct tacatacgat
     7201 gtaccgctgt tctctttacg atttttagct gtactggtga attatgagca atctgaatcc
     7261 atgcatgacg tgtggtgcct gttgtgcatt tttccgcgtc tctttttact gggccgaagc
     7321 cgacgatgct ggcggtacta ttcccgccag gctcactgaa caaatatccc cttttcaccg
     7381 atgcatgagc ggtaccaatc agaaaaaccc ccgatgtatt gcccttgcag gaaccccggg
     7441 caaaaatgcc tgctgcacga tatataaaaa tcgatcgtcc acatgcagag aattcgccat
     7501 gtctggtgag aacggagtcg tcaatgaggc ttgcaatcgt gcaagggcta aatacgggct
     7561 gacaccgtta taaacataca ataattaatt gcaatgcccc gccagcgata atagcggggc
     7621 ttcgtttttc aggggtaaca aaacccgata cttcttctat ttgccagcaa caatgcctct
     7681 cttctgtagc gttcttcgga tctacatcat cctgaagtag cgcgatatac tcactgacta
     7741 tctgcatcag aatataaaaa gcaatgtttt taacctataa aaatggcgct gtatttgcgc
     7801 catttttatc attcaatgca ttatctgttt gagcctaaag ggatctcagg gtctggctca
     7861 tgagtaattc tgtttcgtaa atctctgcga ataatttcaa tagaccagaa ccagactaaa
     7921 tgtccaaaaa tttcagaaac attctcatac cacgggagat caaacagagg tggcgtcagt
     7981 cccatgagag ggaatgaaat catatgaaca aaaagttggg ctaaagcacc tgccagtaag
     8041 ccctgccaga gtttaatttt tggaaatact tcagcgacca cacaataacc gacagcaaac
     8101 actatcgaaa agataatgtg cgtaacacca acccagttaa agacatgccc ggcaaaggta
     8161 taaacagccg cattgggatc tgtcagcccc aaccagtctc gaagaaaaat atacggtgga
     8221 ttgagaaaat tacgcgagca atcaatttgg cctgcagccc tgattaatga ttccgggcca
     8281 cacgctgcat taaacatatc caccgggcta cgtggcggca atggaacttc agccccccac
     8341 ttcacgaatg cggaaacaac gccagcaatc agcccaatga atgcagcaag accataacgt
     8401 ctgcggttcg gtggagtttg ttcaaatata ttcatatcta ccctgcttgt accattatgt
     8461 tatacacctc ttcaggagta ttcataaaac aaggcaaatg taaagaactg tattgttttg
     8521 tataacaaga tggtttccta atcgccaatg aatataagct ccatcatttc tccctatttt
     8581 tatattagaa gtgacagaga tttgcagggt gatgcagagc tgaaaatcac aggtttcctt
     8641 attggttttt gcatcgtaca actaaagcaa taaaccagct cccatcatca tcaacatccc
     8701 ggcgaacatg aatttattag ccgggctcat agctgcattc gcgttttaag aataatcctc
     8761 ctgctgtcgc cgactatgct taacatttaa aaaagcatca gcactctcgc aacgcactct
     8821 tattttcccc tttagaatac cggaggcctg gtatgagcaa ccaaggcgaa taccccgaag
     8881 ataatcgggt tgggaagcac gagccgcacg atttaagttt gacccgtcgc gatctgatta
     8941 aagtgagcgc cgcaacagcg gcgaccgccg tggtttatcc tcattctacg ctggcggcaa
     9001 gcgttccggc agctacaccc gcgccagaga taatgcccct gacactgaag gtgaacggca
     9061 aaaccgagca gcttgaggtg gatacccgaa ccacgctact ggacgctttg cgtgaaaatc
     9121 tgcatttgat cggtaccaag aaaggttgcg atcacggaca gtgcggagcc tgtaccgtgc
     9181 tggtcaatgg tcgcaggctt aatgcctgcc tgacgcttgc agtcatgcat cagggggccg
     9241 agatcaccac cattgaaggc ctgggttcgc cagataatct tcaccccatg caggcggcct
     9301 ttatcaagca tgatggcttc cagtgcggct actgcacctc cgggcaaatt tgctcatcag
     9361 tagcggtgct aaaagagatt caggacggca ttcccagtca cgtcacggtc gatttggttt
     9421 ccgctccaga aacaactgcc gatgagatcc gtgaacgtat gagcggcaac atctgtcgct
     9481 gtggtgcata cgctaacatc cttgccgcca ttgaagatgc tgcgggggag ataaaatcat
     9541 gaaggcgttt acctatgaac gagtgaacac cccagccgag gcggcactta gcgctcagcg
     9601 cgtacccggc gcaaaattta tcgcgggcgg gaccaatctg ctggacctga tgaagctgga
     9661 aattgaaacg cccacccacc ttatcgatgt gaacggcctc gggctcgata agattgaagt
     9721 gaccgacgcg ggtgggctgc gcatcggcgc actggtacgg aacaccgacc tggcggctca
     9781 cgagcgcgtg cgtcgtgatt acgcggtact ctcccgcgcc ctgctcgctg gcgcatctgg
     9841 tcagttacgt aatcaggcaa ccaccgcagg taatctgctc cagcgcacgc gctgccccta
     9901 tttttacgac accaatcagc cctgcaataa gcgcctgccc gggagcggct gcgcggcgct
     9961 tgaaggcttt agccgtcagc acgcggtggt aggcgtaagt gaagcctgca tagccaccca
    10021 tccgagcgat atggcggtcg caatgcggtt gctggatgcg gtggtggaaa ccatcacgcc
    10081 ggagggaaag actcgcagta tcacactggc tgatttttat cacccaccgg ggaaaacgcc
    10141 gcacattgaa accgccctgc ttcccggtga gcttatcgtt gcggtgacgt tacctccacc
    10201 gctcggcgga aaacatatct accgtaaggt gcgcgatcgc gcctcctacg cctttgccct
    10261 ggtatcggtc gcggcgatta ttcagcctga cggcagcggg cgcgtcgcgc tgggcggagt
    10321 agcacataag ccctggcgca ttgaggctgc ggatgctcag ctatcccagg gggcgcaggc
    10381 cgtatatgac acgctgttcg ccagcgccca tcccaccgct gaaaacacct ttaaactcct
    10441 gttggcgaag cgaacgcttg cctccgtact ggctgaagcg agggcacagg catgaaattt
    10501 gataaacccg caggggaaaa cccgatcgat cagctgaagg ttgtcggtcg tccccatgac
    10561 cgcatcgacg gaccgctgaa aactaccggc acggcacgct acgcctacga atggcatgaa
    10621 gaggccccca acgccgccta tggctatatc gtcggttccg ccattgccaa aggacgcctc
    10681 accgcccttg atacggacgc cgcgcaaaaa gcgccgggcg tactggctgt cattaccgcc
    10741 agtaacgccg gggcactcgg caaaggcgac aaaaacaccg ccaggctgtt aggcggcccc
    10801 actattgagc actatcatca ggccattgcg ctggtagtgg ccgagacctt cgaacaggcg
    10861 cgagcggcgg cctcgctggt gcaggcacac tatcgccgta ataaaggagc ttactccctg
    10921 gcggacgaaa aacaggccgt caatcagccg ccggaagaca cgcccgacaa aaacgtcggt
    10981 gactttgacg gggctttcac ctccgctgcg gtgaagattg atgctaccta cacgaccccg
    11041 gaccagagcc atatggcgat ggagccgcat gcctcgatgg ccgtctggga tggaaataag
    11101 cttaccctct ggacctcaaa tcagatgatt gactggtgcc gcaccgatct ggcaaaaacg
    11161 ctgaaagttc ccgtggagaa tgtgcgtatt atctccccgt atatcggcgg agggtttggc
    11221 ggcaagctgt tcctgagaag cgatgcgctg ctggcggccc tcgccgcccg agcggtgaaa
    11281 cgtccggtta aagtgatgct cccccgcccc tctattccca ataacaccac gcaccgcccc
    11341 gccacccttc agcacttgcg tatcggtgcc gaccagagcg ggaaaatcac cgctatctca
    11401 catgaaagct ggtctggaaa cctgcccggc ggcacgccgg aaacggcggt acagcaaagc
    11461 gaattactct acgccggggc gaatcgtcat accggcctgc ggctcgccac gcttgatttg
    11521 ccggaaggga acgccatgcg tgcgcccggc gaagcccccg gtctgatggc gctcgaaatc
    11581 gcgatcgacg aactggcgga aaaagcgggc atcgatcccg tcgagtttcg catcctgaat
    11641 gacactcagg ttgaccccgc cgacccgacg cgctgcttct ctcgccgtca gcttatcgag
    11701 tgcttgcgca ccggagcgga taaatttggc tggaagcagc gcaacgccac acccggacag
    11761 gtgcgcgacg gggagtggct agtcggccac ggtgttgcgg cgggctttcg caataatctg
    11821 ctggaaaaat cgggtgctcg ggttcacctc gaacaaaacg gcaccgttac cgtagaaacg
    11881 gacatgaccg acattggcac cggcagctac accattctgg cccagacggc agcggaaatg
    11941 cttggcgtac cgctggagca ggttgcggtt cacctcggcg attccagttt cccggtttct
    12001 gcgggttctg gtggacaatg gggcgcgaat acctccacct ccggcgttta cgccgcctgt
    12061 atgaagcttc gcgaaatgat tgcctcggca gtcgggtttg atcctgagca gtcgcagttt
    12121 gccgacggca agattaccaa cggtacccga agcgccacgc tacatgaagc caccgcaggc
    12181 ggcagactga cagcggaaga gagcattgaa ttcggaacac tgagcaaaga gtaccagcag
    12241 tcgacctttg ccgggcattt tgtggaggtc ggcgtgcata gcgcgacggg agaagttcgg
    12301 gtccggcgta tgctcgctgt gtgtgctgca ggacgcatcc tgaatccgaa aactgcgcgc
    12361 agccaggtca ttggcgcaat gactatgggc atgggcgcgg cactgatgga ggagctggcg
    12421 gtggatgacc gtttgggcta cttcgttaat cacgatatgg cggggtatga ggtgccggtc
    12481 catgcggata tcccaaaaca ggaggtgatt ttcctggatg ataccgaccc catatcctcc
    12541 ccgatgaagg ccaagggtgt cggtgagctg ggcctgtgcg gcgtgagcgc ggctatcgcc
    12601 aacgcggtgt ataacgccac cggtattcgg gtacgcgatt atcccatcac tctggataag
    12661 ctgctcgata agctgccgga tgtggtttaa ggagaaacaa tgtcataccc gctttttgat
    12721 aaagacgaac actggcataa gccagagcag gcgtttctca ccgatgacca ccggaccatt
    12781 ctgcgcttcg ccgtagaggc gctaatgtcc ggtaaaggag cggtgctggt gacgctggtg
    12841 gagatacgcg gcggcgcggc gcgcccgctc ggggcgcaga tggtggtgcg cgaagatggt
    12901 cgttactgcg gttttgtctc tggcggctgc gtggaggccg ctgccgcttt tgaagcgctg
    12961 gagatgatgg gctcaggccg cgatcgcgaa attcgctatg gcgaaggttc gccgtggttt
    13021 gacatcgttc tgccctgcgg cggtgggatc acgctgacgc tccataaact acgctcggca
    13081 cagcctctgc tcgccgtgct gaaccgcctg gaacagagaa aaccggcggg gctgcgctac
    13141 gatccgcaag cacaatcgtt ggtgtgcctg cccacgcaaa cccgaacggg ctggaatctc
    13201 aatggctttg aggtggggtt caggccatgc gtcaggctga tgatttacgg acgttctctt
    13261 gaggcgcagg caaccgcgag tcttgcagca gccacaggct atgacagcca tatcttcgat
    13321 ctttttccgg cctcagccag cgctcagatc gataccgata cggcggtcat tttgctgtgc
    13381 catgatctca accgggagct gccagtgttg caggccgcgc gagaagcaaa acccttttat
    13441 ctcggcgcat tgggcagcca tcgaacccac acgttacgtc tgcaaaagct ccacgagctg
    13501 ggatggtcca gggaggagac agcgcaaatc cgggcccccg tcgggatatt ccccaaagcc
    13561 cgggatgcgc atactctggc actctccgtg ctggcagaaa tcgcctctgt acgtctccat
    13621 caggaggagg attcatgcct gcccccgtcg tcctgatcct tgcggccggg cgtggaaagc
    13681 gctttctcgc ctccgaggga aatacccata agtgtatcgg ctggcgtcag tccccggagg
    13741 ttgcgcctta tcgctggcca tttgaagaaa acgggagaac tttcgacctt gcgattgaac
    13801 cgcagattac gactaatgat ctgcgtctga tgttgaggct ggttcttgcc ggcggaggaa
    13861 taacaattgc cactcaggaa actttcaggc catatattga aagcggtaag cttgtatcgc
    13921 tgcttgatga ctttcttcca caatttccgg gcttctatct gtatttccca cagcgtcgca
    13981 atattgcacc aaagctccgc accctgattg actacgtcaa agaatggcgg cagcaattgg
    14041 cttaaatagc tgcacctgca ctgcctgatg tcagaacagt attttgatga attgccaagg
    14101 ttacaatggc acaaatgcgg cacaggagga aacgtggtgt atttaaatat ggggtaactc
    14161 tttgatttta atggtgccga taataggagt cgaacctacg accttcgcat tacgaatgcg
    14221 ctgctctacc aactgagcta tatcggccct gaaaggacat gttcacgaac gtgaatcacg
    14281 gtggacaagg ttaaaactaa ccgggcgatg cgtcaatggc cttgtgaatc aaatggctac
    14341 ttttgcatca cccggtttta tttacgcacg aatggtgtaa tcaccaatgc cgatccactt
    14401 gtaagtggtc agtgcttcca gccccattgg gccacgcgcg tggagttttt gtgtgcttac
    14461 cgccacttcc gcacccagac caaactggcc gccgtcggta aaacgcgtag aggcgttaac
    14521 gtaaacagcg gacgaatcca cttcgttaac aaaacgctgg gcgttgcgca tatcgcgggt
    14581 caggatcgca tcggagtgtt gtgtgccgtg ttcacgaata tgggcgatgg catcgtcaag
    14641 atcgctgacg attttgacgt tcaaatctaa tgacagaaac tcatcgtcat actcttcggc
    14701 tttaacagca accaccttcg cagggcctgc ctgcaactgc gccagtgcag ctgcatctgc
    14761 gtgtaatgtc acgccgcttt ccgccatttg tttgcttaat gcgggcagga agctatcggc
    14821 gatgttttta ttcaccagca acgtttcaac cgtattacat gtgctcggac gctgagtttt
    14881 cgcgttgacg atcactttta atgcttcagc gatctctaca ctttcatcaa cgtaaatatg
    14941 gcatacgcct ataccacctg tgatcaccgg gattgtcgac tgttcacggc acagtttatg
    15001 caaaccagcg ccaccacgcg ggatcagcat gtcgatgtat ttatccatac gcagcatttc
    15061 actgaccagc gcacggtcag gattatcaat cgcctgcacg gcacccgccg gtaagccgca
    15121 ggatttcagg gcgtcctgaa tcaccgccac cgttgcagcg ttagtgcgac acgtttcttt
    15181 gccaccgcgc aggatcaccg cattaccggt tttcaggcac agcgaagcga catcaaccgt
    15241 cacgttcggg cgcgcttcat aaatcacgcc aataaccccc agcggtacgc gacgacgctc
    15301 aagacgcagg ccgctgtcca gtacgctgcc atcgattacc tgccccaccg gatcggcgag
    15361 gttacacacc tggcgcacat catcggcaat gcctttcagc cgtgcgggcg tcagtgccag
    15421 acggtcaagc atcgcttcgc caaggccatt ggcacgcgcg tcagcaacat cctgggcgtt
    15481 agcgttgagg atgatttcgc tttgtgcttc cagttcatcg gcgatttttt ccagcacgcg
    15541 atttttttcg cggctggaga gttgcgctaa tttatacgag gcttgcttcg cggcaatgcc
    15601 catttgttcc agcatcagcc tgctccttaa cgggtaatca tgtcatcacg gtgaacggca
    15661 accgggccgt attcatatcc cagtattgca tcaatttctt gcgagtggtg cccggcaata
    15721 cggcgtaatg catcgctgtt gtaacgactg acgccgtggg cgatatcgcg accttcgagg
    15781 ttgcaaatgc ggatgacttc accacgcgag aaattgccag tcacgctttt aatgcctttc
    15841 ggcaacaggg agctgccgcg ttcaagaatg gcggcagttg ccccttcatc taccgtgatt
    15901 tcacccgccg gcggcgcacc gaaaatccag cgtttacggt tttcaagcgg agtcgcctgg
    15961 gcatggaaca gcgtaccgac ggaaatgcct tccatcacat caccaataac gcccggcttg
    16021 ctgcccgcgg caataatggt gtcgataccc gcacggcaag ccacgtcagc ggcctgcaat
    16081 ttggtactca tgccgccagt tccgaggcct gaaacgctgt caccggcaat cgcgcgcagt
    16141 gcgtcatcaa tgccgtaaac atctttaatc agttctgcct gcggattgct gcgcggatca
    16201 gcggtataca aacctttttg atcggtcagc agcaacagtt tatcggcacc cgccagaatc
    16261 gccgccagcg cagaaaggtt atcgttatcg ccgaccttaa tctctgccgt agcgacagca
    16321 tcgttctcat tgattaccgg aacgatattg ttatcgagca acgcacgcag ggtgtcgcgg
    16381 gcgttcagga agcgttcacg gtcttccata tcagcacggg tcagcagcat ctgcccgacg
    16441 tgaatgccat aaatcgaaaa cagctgttcc cacagttgaa tcagtcgact ctgccctacc
    16501 gccgccagca gttgtttcga ggcgatagtc gctggcagtt ccgggtaccc caggtgctca
    16561 cgtccggcgg cgatcgcgcc cgacgtcaca ataacaatcc gatgcccggc ggcatgtaac
    16621 tgcgcgcact ggcgaacaag ttcaacgata tgggcacggt tcagacggcg cgatccgcct
    16681 gttagcacac tggtgccgag ttttaccacc agcgtctggc tgtcactcat gattctctgc
    16741 cattcaattt taggaaaaat gatatcaaac gaacgtttta gcaggactgt cgtcggttgc
    16801 caaccatctg caagcaaagc atggcgtttt gttgcgcggg atcagcaagc ctagcggcag
    16861 ttgtttacgc ttttattaca gatttaataa attaccacat tttaagaata ttattaatct
    16921 gtaatatatc tttaacaatc tcaggttaaa aactttcctg ttttcaacgg ggctctcccg
    16981 ctgaatattc gcgcgttaat taaaatcagg aatgaaaatg aaaaagagca ctctggcatt
    17041 agtggtgatg ggcattgtgg catctgcatc cgtacaggcc gcagaaatat ataacaaaga
    17101 cggtaataaa ctggatgtct atggcaaagt taaagccatg cattatatga gtgataacga
    17161 cagtaaagat ggcgaccaga gttatatccg ttttggtttt aaaggcgaaa cacaaattaa
    17221 cgatcaactg actggctatg gccgttggga agcggagttt gccggaaata aagcggagag
    17281 tgatactgca cagcaaaaaa cgcgtctcgc ttttgccgga ttgaagtata aagatttggg
    17341 ttctttcgac tatggccgta acctgggcgc gttgtatgac gtggaagcct ggaccgatat
    17401 gttcccggaa tttggtggcg actcctcggc gcagaccgac aactttatga ccaaacgcgc
    17461 cagcggtctg gcgacgtatc ggaacaccga cttcttcggc gttatcgatg gcctgaactt
    17521 aaccctgcaa tatcaaggga aaaacgaaaa ccgcgacgtt aaaaagcaaa acggcgatgg
    17581 cttcggcacg tcattgacat atgactttgg cggcagcgat ttcgccatta gtggggccta
    17641 taccaactca gatcgcacca acgagcagaa cctgcaaagc cgtggcacag gcaagcgtgc
    17701 agaagcatgg gctacaggtc tgaaatacga tgccaataat atttatctgg caacttttta
    17761 ttctgaaaca cgcaaaatga cgccaataac tggcggcttt gccaataaga cacagaactt
    17821 tgaagcggtc gctcaatacc agtttgactt tggtctgcgt ccatcgctgg gttatgtctt
    17881 atcgaaaggg aaagatattg aaggtatcgg tggtgaagat ctggttaatt atatcgacgt
    17941 cggtgctacg tattatttca acaaaaatat gtcagcattt gttgattata aaatcaacca
    18001 actggatagc gataacaaat tgaatattaa taatgatgat attgtcgcga ttgggatgac
    18061 gtatcagttt taatagatat tgccggatgt gatgcatccg gcacatttca ctcacgccgt
    18121 taacttcacc ggctcgtcac gaaaatcatc cgccggttcc agcttcagat tcagcgtcgt
    18181 cagcagttca cgcagcttct cgtgaaactc acgcagggtg tgctccagtc gttcaaccac
    18241 ttcagtatct tttaccggaa cactcttcca gtcgcctgct ttatcgaaca gaccaaactg
    18301 gtagctgtag gtaaaacggg attcctgcgc ttccagctcc atccaccagc cccagaattc
    18361 acgcacttcc ggtgccggtt tcacgttgac gcatacagcc agacaatcga aaaagaatcg
    18421 attatcttcg cacttacctt cacgaatata cgggcctagt gcggtaaatt ttttgatcaa
    18481 tctgctcttc gggtgtccac tcggtaacgt cattgctatc tcctgttgtg atgcaactgt
    18541 tttaccaaat tggcaaaatt tagcaaattt ttaacacaag cgtttttcga tccagccggt
    18601 gatttcctga agacctttgt caaaattccg atacaccggg ttaaatggga tctctaataa
    18661 tttaccgtca gcagatgatg aggtgattaa gcgtgagtcc tcttccgggc tgaacggatc
    18721 gttcttccag tagcctgata acattggcgt tgggcagcga cgtcccagca atccttgcac
    18781 ttttaatgaa tagcgattca gctccacgcg taacgcttcg tcggaagcat catgcatccc
    18841 caaacgactc gccagaacgt caagatacat ttccggcacc tgttgctggc acttaaaatc
    18901 actcaacagg gtatgaacta ccggaccaag acaggcaacc gctttcagac gcggcgattc
    18961 aaggtatgcc agacgcacgg caacgttagc gccgaaacgg aaaccaaagg ccgcgacgcg
    19021 agtgtgatcc acccacggta cgttaggcag cgcctttaag acgtgctgat gcaacaggct
    19081 ggagtcctgg gtgagcttcc attttgaaga aaagcccacc gacggcatat caatagtcag
    19141 catcgcaatg ccgcgcggcg caaaataacg ttcatacagg ctgtaatagt ccgtctgcat
    19201 cgcatccaga ccaccacaca ttaatactgt cgggaacggg ccatcgcctt tcggcatatg
    19261 caaaaagccg gtgatgggcg caccgccggg tacagtaaac tccatctgcc gcatcgtgcc
    19321 cggcagacgc tgggcggcct cttcataggc gcggtttgat aaagcctgcg cttgctcggc
    19381 caggtcatct cctttcagat gaggataggc ggcaatgttg tacaacgtag ccgcatgcag
    19441 ccagtgtcga ccactgagtt gcggatcttc ttccgcacag gctttttgtt gccacaccat
    19501 cgcctgggtg gcccactcat aaatccagtt gccaccacgg tagccaatca cagtatcgta
    19561 taaatcatcg tcggtacgtt cagcatcgct catcacaata cgtgcctgga cgtctaggat
    19621 ttcacgtggg tcaataccgc gccagatcca catcagacgg ttaatcatgc gataccagtg
    19681 agggatggtt ttaccatcaa gagccgactg cacaggcggt tgtgcgccgt gattaaagcg
    19741 gcggactagc gtcgaggttt caggatgttt aaagcggggt ttgaacaggg tttcgctcag
    19801 gtttgcctgt gtcatggatg cagcctccag aatacttact ggaaactatt gtaacccgcc
    19861 tgaagttaaa aagaacaacg cccggcagtg ccaggcgttg aaaagattag cgaccggaga
    19921 ttggcgggac gaatacgacg cccatatccc acggctgttc gatccaggta tcttgcggga
    19981 tatcaacaac ataatcatca accagcggac gaccagccgg ttttgcaaag atggtgacaa
    20041 agtgcgcttt tggatacatt tcacgaatcg caaccgcagt accaccggta tccaccaggt
    20101 catcaataac gatgaagcct tcgccatcgc cttctgcgcg tttcagcact ttaagctcgc
    20161 gctggttgtc gtgatcgtag ctggaaatac aaacggtatc gacatgacga atacccagtt
    20221 cacgcgccag taacgcaccc ggtaccagac cgccacggct tacggcaata atgcctttcc
    20281 attgttcaga aggcatcagt cggcttgcga gtttacgtgc atggatctgc aacatgtccc
    20341 aggtgacgat gtatttttcg ctcatgtgaa gtgtcccagc ctgtttatct acggcttaaa
    20401 aagtgttcga ggggaaaata ggttgcgcga gattatagag atctggcgca ctaaaaacca
    20461 gtatttcaca tgagtccgcg tctttttacg cactgcctct ccctgacgcg ggataaagtg
    20521 gtattctcaa acatatctcg caagcctgtc ttgtgttgac aacattttct gctaaccctg
    20581 tgacctgcaa tactgttttg cgggtgatcg acaaggagac ttaacgtgtc tgaactgtct
    20641 caattatctc cacagccgct gtgggatatt tttgccaaaa tctgttctat tcctcacccg
    20701 tcctatcatg aagagcaact cgctgaatac attgttggtt gggcaaaaga gaaaggtttc
    20761 catgtcgaac gcgatcaggt aggtaatatc ctgattcgta aacctgctac cgcaggtatg
    20821 gaaaatcgta aaccggtcgt cttacaggcc cacctcgata tggtgccgca gaaaaataac
    20881 gacaccgtgc atgacttcac gaaagatcct atccagcctt atattgatgg cgaatgggtt
    20941 aaagcgcgcg gcaccacgct gggtgcagat aacggcattg gtatggcgtc tgcgctggcg
    21001 gttctggctg acgaaaacgt ggttcacggc ccgctggaag tgctgctgac catgaccgaa
    21061 gaagccggta tggacggtgc gttcggctta cagagcaact ggttgcaggc tgatattctg
    21121 attaacaccg actccgaaga agaaggtgaa atctacatgg gttgtgcggg gggtatcgac
    21181 ttcacctcca acctgcattt agatcgtgaa gcggttccag ctggttttga aaccttcaag
    21241 ttaaccttaa aaggtctgaa aggcggtcac tccggcggtg aaatccacgt tggcctgggt
    21301 aatgccaaca aactactggt gcgcttcctg gcgggtcatg cggaagaact ggatctgcgc
    21361 cttatcgatt tcaacggcgg cacactgcgt aacgccatcc cgcgtgaagc ctttgcgacc
    21421 attgctgtcg cagctgataa agtcgacgtc ctgaaatctc tggtgaatac ctatcaggag
    21481 atcctgaaaa acgagctggc agagaaagag aaaaatctgg ccttgttgct ggactctgta
    21541 gcgaacgata aagctgccct gattgcgaaa tctcgcgata cctttattcg tctgctgaac
    21601 gccaccccga acggtgtgat ccgcaattcc gacgtggcaa aaggtgtggt cgaaacctcc
    21661 ctgaacgtcg gtgtggtgac catgactgac aataacgtag aaattcactg cctgatccgt
    21721 tcactgatcg acagcggtaa agactacgtg gtgagcatgc tggattcgct gggtaaacta
    21781 gctggcgcga aaaccgaagc gaaaggcgca tatcctggct ggcagccgga cgctaattct
    21841 ccggtgatgc atctggtacg tgaaacctat cagcgtctgt tcaacaaaac accgaacatc
    21901 cagattatcc acgcgggcct ggaatgtggt ctgttcaaaa aaccgtatcc ggaaatggac
    21961 atggtttcta tcgggccaac tatcaccggt ccacactctc cggatgagca agttcacatc
    22021 gaaagcgtag gtcattactg gacactgctg actgaactgc tgaaagaaat tccggcgaag
    22081 taattatttg atttgctgcc ggatggcgtt taatcgcctt ccggcagttt catccttcat
    22141 tatccttcga taaaagccat ccctgtaaat gtccgtctcg ggttgccacg ttcaatctgg
    22201 tgatggaaca ttcgccgctg cgatttcagc accgcgctat tttcctgttg ctgctgctcc
    22261 agcttccagg caatcagcaa tcgtgccagc cgcttgttag catgctgact acgctctgac
    22321 tgaaccttca cgctaatacc ggatgccaaa tgcgtggcgc gtaccgccga gtcggtttta
    22381 ttgacatgtt gaccgcccgg ccccgacgaa cgcaacgtct cataacggat tgcatccgat
    22441 tgttcctgct catcagcggt aaaacgccca atgcccagaa accagttttt gcgcccatga
    22501 tgaggccgat acggactcgg acaaatccac tgaatagtgc cgcaccagct ttcgcttaat
    22561 gcccatgcgt tatcgccatc cagagaaacc agagctgaac gcagcgtgtc agagtagcgg
    22621 cccgtttctg tttccaacac cgttaccgcg acgtcttgtc gggcagcttc tttaattagc
    22681 ctgtccagcg cctttttcac tgcgagacaa cattcttccg gcccctgcgc tgaggagagt
    22741 tgtagcaaga tcatcctttt ttccctccac tgtttttgag cgttagcacc ggacgcagcc
    22801 gcgcgacagg aataattaaa ccggcctgca ccagacattg caccacgctt tcagccgatt
    22861 tataggcttg tggcgcttct tcaaagatga gttgtttatc gcgacaaatt acccgactgc
    22921 caagttcagt acgcgagagt tgcgtcgccg tgtatttcgc tgccagacgc cctttacact
    22981 cggtgcgccc ccatttacgc cctgccccat gcgccagcga gtggagcgtt ttttcgttcg
    23041 caacaggctg tacaatccag gagtaatcac cacgtgaacc gggaataatc accagaccgt
    23101 tgtcatccgg cgtggcacct ttacgatgca accagccctg ttgatcgccg atttgacacg
    23161 cgctaacaaa gttatgcgcc acatccagaa ccggacttcc cgtggcctta acttgttgca
    23221 ttatgcgcaa agcgatcatc tggcgattaa tacacgcaaa cgccagcgca tcgtcatgtt
    23281 ccgcaatata ccgtagcgcg tcgtcactgc cttgaggcaa accatgatgc gagaacgagg
    23341 caatatgccg ctgtaaaata gactgcccca ccccccgcga gccgctatga accaacagtt
    23401 gcagatgttg tgcatccaga cctgccagtg caaacagttc agcgttgatg atttgatcaa
    23461 cttgttgcag ttcagcgaaa tgattgccgc caccgataga gccaagcgag ctgcgccacg
    23521 gatgctgtgc aaatgctgac ggcaggtttt cctccagcca gctttcttca gcaacgtcat
    23581 ccagatctga taatcgcttt tcaaacttat cggcgttgta tttgcgagtg agaatatctg
    23641 tttgccatag cgccataccg cagccgatat cattgccgac cagtgccgga taaaaacgac
    23701 caacagagaa gaacgctgcg ccaatcggat agccgcgtcc gggatgtaaa tctggcatcc
    23761 ccactacgcg ctgcatgttg ggtaaatttg ccgtggtgtg taattgttgg atcgctaaac
    23821 tctcgatcca caggtcatca gatgcgatgg taaataccgc atcggataag ggacgaatat
    23881 aattgcccat ataccattcc gtaaatagac tcgtcatact tcaagttgca tgtgttgcga
    23941 cttgaattat tgagagtaac aattaaaaaa tcaggaaatg gcagacgaat ccagggcaag
    24001 aaaaaaagaa ttaatcctgg aaaggtctgc aaagagtcat tgataaagga tttgtcatga
    24061 tttacctcct tgcagtttgt ggaataagaa aacgcgcaca tactaggctt gcgttatttt
    24121 cattgcaagc tggatttaat gttgctgttt ataacgcata taaaaattaa taaaccactc
    24181 tccccgacat tcaacgcgtt gctgcttaac tgtctgaaaa ccataacgtt caaaaaaggg
    24241 ttttgcggtt atgcttgcgt ccaccgtaag ttcggattca gacttaatca aaggttttaa
    24301 caaagcgctg gcaaccccac ggcgggtgta ttcagggtca acaaataaca tatcgatata
    24361 gtgttcaacg caggtaataa agccgaccag ttttgcatta atgactgcaa cccgcacttg
    24421 tgatttcgcg agtttctcct tccagcgaga ttcgtcaatc tgcgcccagg cggcaatttg
    24481 ttgtggtgaa taatgctgac tggcagtcat cgtaaccgct ctaatgaaaa tagcgcatag
    24541 ttgctgaaaa tcgccaggct gatagtctct tatttgtatg ttattcataa tcccagcacc
    24601 agttgtcttt ccatttgcgg gtcaagcaac gtcacatgca gccccaccag tcgcacaccg
    24661 cgcccgccgc ggcgttcatc ccaggtttta cgcgcggtgg cgattaagtc agctttattc
    24721 agccgcggcc agacgtgctc ctgagtggtt tgctgaaaat cgtcgaactt taatttcacc
    24781 ccctggcggg caatcagtaa atcaggtttt acctttgcca gacggcgttc aagttccgga
    24841 tacagccgct cgataatcgc ttcacattca gaccagtggt ggatatcttc cgccatcgtg
    24901 cgttccacgc cgacggattt tcgcaaccgt tcgctgttaa cgtcgcgctc gtcaatcccc
    24961 tgactacgct cccacaaaat gcggccaaat ttgccaaagc gtttaagcag catcaccaga
    25021 tcacactttt gtacatcacc gcaggtccgc agccccatcg cttccagttt tgccgccgag
    25081 actttgccga cgccggggat ttttgccagc ggtaaggttt gtaaaaatgc cggaacttct
    25141 gccggcgtaa tcacaaactg accgttgggt ttattcatgt cggaggcgat tttggcgaga
    25201 aactttactg gtgccacgcc cgcagacgcc gtcagttgca gctcgctgaa aatcgtctgg
    25261 cggatttcct gggcgatgag ggtcgcagaa ccgtggcaat ggacgctatc ggtgacgtcg
    25321 agataagcct catccagtga caacggttca atacgcgagg tgtagcgcga gaagatttca
    25381 cggatatgat ttgaggcttc tttgtaggcg tcaaagcgcc ccggaagcaa ggtgagatgc
    25441 gggcataatt tgagcgccat ccctgtcggc atagcgctac gtacgccaaa tttacgcgcg
    25501 ggataattgg cggtgctgat caccccccga cgttcgcggc tgccgccaat agcaataggg
    25561 atatcgcgca gggcgggatt gtcgcgcatc tccaccgctg cgaaaaagca gtccatatcc
    25621 acatgaatga ttttacgcat tactcacctc tcaacactgg taaagtatac agtgatttca
    25681 gggtttgaga aatgcgtaaa gattcagcat ttaacgcgtt cgctgcgaaa gcacctgctg
    25741 cttatccagc ttttgcacca gcggctgcac cactttatcc ccatgctgac caaagtattg
    25801 atacagcgta tcggacgcac ttttggtcag caccataatc tcaatgcgcc ggttgcccgc
    25861 gctttgcgga tttttggaat ccagcagcat ctggtccgcc attgcgctta cctgcatcac
    25921 tttatcttcc ggcattccgg cctcttccag cacccgacga gctgaaagcg cgcgatcgcc
    25981 cgaaaggttc cagttgttgt agatattgtt tttgtaggcc atcgcatcgg tatgcccggt
    26041 aataataatt ttgttatcga gcgagtcgaa aactggcgcg agctccacca gcagcctttt
    26101 aaagaacggc ataatctgcg cgctgccgcg ttcgaacata ttgcgattct ggtcgtcttt
    26161 aatcagcacg cgtaatccct gcgggacaat ctccatctcc agattcgctt ccatatgcgc
    26221 atcacgggca atggtgttga tactggttgc cagctcgcca agctcggtgg cggatttctt
    26281 cttcagcagc accgttttct cattgacgtc acgcgctttt ttctccgtct cttccggcac
    26341 cgccacggtg gcaggttttg gcggatgaga cgggctgatt ttatttaacg gcgacagccc
    26401 accaccgtta aaaatcgact gcccgtgcag cgcggcgata atgctttcac gctcggattt
    26461 actgacgctg ttgacaatca actttattgt cgtcaccaaa ggggccgagc gtatttccga
    26521 ggtttcagcc cgctttaccc tggatgcgat gcccggtaag cagatggcga ttgacgccga
    26581 tcttaatgcc gggttgatca atcaggcgca ggcacaaacc cgacgtaaag atgttgccag
    26641 cgaggccgat ttctacggcg cgatggacgg ggcatcgaaa tttgtgcgcg gggatgctat
    26701 cgccgggatg atgattctgg cgatcaacct gatcggcggc gtctgtatcg ggatcttcaa
    26761 atacaacctg agcgccgacg ccgccttcca gcagtatgtg ctgatgacca tcggcgacgg
    26821 gctggtggcg caaatccctt ccctgctact ctccaccgcg gcggcgatta tcgtcacccg
    26881 cgtcagcgac aacggcgata tcgcccatga cgtgcgtaac cagttgctgg caagcccgtc
    26941 ggtgctctac accgctaccg gaattatgtt cgtactggcg gtagtgccgg gaatgccaca
    27001 tctgccgttt ttgctgttca gcgccctgct tggctttacc ggctggcgga tgagcaaacg
    27061 cccgcaggcg gcggaagcgg aagagaaaag tctcgaaacg ctgacccgca ccatcaccga
    27121 aaccagcgag caacaggtca gttgggaaac cattccgctg atcgagccca tcagcttaag
    27181 cctcggctac aagctggtgg cgctggtgga taaagcgcag ggcaacccgc tcacccagcg
    27241 gattcgcggc gtgcggcagg tgatatccga cggtaacggc gtgctgctgc cggagatccg
    27301 tattcgggaa aacttccgcc tcaagcccag ccagtacgct attttcatca acggcattaa
    27361 ggctgatgaa gcggatattc cggcggataa actgatggcc ctaccctcca gcgaaaccta
    27421 cggcgaaatt gacggcgtgc tggggaacga cccggcgtac gggatgccgg tgacctggat
    27481 ccagcccgcg cagaaagcga aggcgctgaa tatggggtat caggtgatcg acagcgccag
    27541 cgtgattgcc acgcatgtga ataagattgt gcgtagctat attcctgatt tatttaacta
    27601 tgacgatatt acgcagttgc ataaccgttt gtcgtcgatg gcaccgcgcc tggcggaaga
    27661 tttaagcgcg gcgctgaatt acagccagtt gctgaaagtg taccgcgcgc tgctgaccga
    27721 aggcgtttcc ctgcgcgata tcgtcaccat tgccaccgtg ctggtcgcca gtagcgcggt
    27781 gaccaaagat catattctgc tggcagctga tgtgcgcctg gcgctgcggc gcagcattac
    27841 ccatccgttc gttcgcaagc aggagctgac ggtgtatacc ctgaataatg agctggaaaa
    27901 tctgctgacc aacgtggtga atcaggcgca acagggcggg aaagtgatgc tcgacagcgt
    27961 gccggtcgat ccgaatatgc tcaaccagtt ccagagtacg atgccgcagg tgaaggagca
    28021 gatgaaagcg gcggggaaag acccggtgct gctggtgccg ccgcagttgc gccctttgct
    28081 ggcacgctat gcgaggttgt ttgcgccggg gctgcatgtg ctgtcgtata atgaagtgcc
    28141 ggatgagctg gagttgaaga ttatgggagc gttgagttga tgaggattct tttccatgct
    28201 ttgcatgcat ctgacaccat tgattgacgt cacattgcaa acatactacg atgacaccat
    28261 acaatgacgt catggattga tagtatgatt aaggtcagcg cgctaggctc ccgccataga
    28321 aaaacattcg acgatgtaat gacggagccg ccaaaatctg gaattaaatg ggatgatgtt
    28381 gttgcgctca ttaaagcggt gggtggaaca ataaaaaata acaatgggtc cagaaggaaa
    28441 tttcagattg gaacgaccaa attcagtaca catgagccac atccaaagaa tgtgatggat
    28501 aaaggtgcag tagcaggtct taaggagtgg tttgttaact gtgtaggggg agattatgaa
    28561 taaagcatcg aacattatca caattaaagg tcaaccagcc gcagtgacat ttgaagccga
    28621 tatcaacgca tttcgcggca agttcctcaa tgtaaacggt tattgtgact ttgtagccac
    28681 aagcattgag gcattatatc gtgagggcga aagcgcgctg gatgagtgga tggcggattg
    28741 tgaagaggac ggtattgccc cttttcgtga agaagaagag caaaaacgcc tgacgcttcg
    28801 tgttcctcat cacattgatt cgcggctgac catcgtcgcc agacaacatt ccatttcaaa
    28861 aaaccagctc attgttgatg tcttagaacg tgagttttca gcccatatgt aaacaagtcg
    28921 gatgccgcgt ggcatccggc cttttgccag ttcgtcaata ttacccattt acaaaatcgt
    28981 ctcttccgtc aaaatcctgc gcgcgcccaa aaaatggtcc tgccagaaag gttcggctaa
    29041 ccggcttacc cgaatggttt ccccggtgcg cggcgactcg ataaactggc catcgcccag
    29101 atacaccccc atatgatcgg caatctcgcg gctgtggata tggaaaaaca gcaaatctcc
    29161 ccggcgcagg tcgttattcg ccacaatcgt tgcccgatgg tagtgataca tctcgttggc
    29221 cgtgcgtggg agcttcgcct caaggatctt gttgtaggca tagaaaacca acccgctaca
    29281 gtcgaagcct tgatcgggcc gcgtgccgcc ccatacgtaa ggcttgccaa gctgttgctc
    29341 cagacggtga atcgctactt cggtgatgtt atgcagatgg tcgctgctta agaaatggtt
    29401 gttttccgcc agcgcctgcc agcgtctgtc actcgccttg agcggcgcag gaaaccattc
    29461 tggatgctgt tttatctgtt cgcggttgtg ctggcgtagc gcccttctgc tttcggcatt
    29521 gccttccaca atatagctgg cctgtttttt cagatgggtt tggtactgtt ttaataaacg
    29581 cgcacgattt tgcatccgct ggcgggcggc gtagctgaaa gtgatatgtg atgtggtggc
    29641 gctggcaaat gaagaaaacg gcaagcaaag caacagtaat cccgacaaca caaaagaggg
    29701 aatcgacggc aaggacatac tcaataatgg ctgatcatgc attgatgttg cagtgtatcc
    29761 cggcccgtac ctgaacaaac ttaataaacc attattataa aattaataaa tatatttcag
    29821 ttaattatgt aaaaacatcc gtttattaaa ttactcatgg
//
LOCUS       DAPGUL010000051        29497 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.051, whole genome shotgun sequence.
ACCESSION   DAPGUL010000051 DAPGUL010000000
VERSION     DAPGUL010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 29497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29497
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.051"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..212)
                     /locus_tag="RHX21_002439"
     CDS             complement(<1..212)
                     /locus_tag="RHX21_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2542 family protein"
                     /protein_id="HDV1987606.1"
                     /translation="MDVQQFFVVAVFFLIPIFCFREAWKGWRAGAIDKRVKNAPEPVY
                     VWRAKNPGLFFAYMVAYIGFGILSIG"
     gene            complement(215..934)
                     /gene="sanA"
                     /locus_tag="RHX21_002440"
     CDS             complement(215..934)
                     /gene="sanA"
                     /locus_tag="RHX21_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane permeability protein SanA"
                     /protein_id="HDV1987607.1"
                     /translation="MLKRVFLSLLVLIGLLLLTVLGLDRWMSWKTAPYIYDELQDLPY
                     RQVGVVLGTAKYYRTGVINQYYRYRIQGAINAYNSGKVNYLLLSGDNALQSYNEPMTM
                     RKDLIAAGVDPSDIVLDYAGFRTLDSIVRTRKVFDTNDFIIITQRFHCERALFIALHM
                     GIQAQCYAVPSPKDMLSVRIREFAARFGALADLYIFKREPRFLGPLVPIPAMHQVPED
                     AQGYPAVTPEQLLELQKKQGK"
     gene            complement(1084..1968)
                     /gene="cdd"
                     /locus_tag="RHX21_002441"
     CDS             complement(1084..1968)
                     /gene="cdd"
                     /locus_tag="RHX21_002441"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDV1987608.1"
                     /translation="MHPRFQTAFAQLADNLQSALEPILADKYFPALLTGEQVSSLKSA
                     TGLDEDALAFALLPLAAACARTPLSNFNVGAIARGVSGTWYFGANMEFIGATMQQTVH
                     AEQSAISHAWLSGEKALAAITVNYTPCGHCRQFMNELNSGLDLRIHLPGREAHALRDY
                     LPDAFGPKDLEIKTLLMDEQDHGYALTGDALSQAAIAAANRSHMPYSKSPSGVALECK
                     DGRIFSGSYAENAAFNPTLPPLQGALILLNLKGYDYPDIQRAVLAENADAPLIQWDAT
                     SATLKALGCHSIDRVLLA"
     gene            complement(2098..2793)
                     /locus_tag="RHX21_002442"
     CDS             complement(2098..2793)
                     /locus_tag="RHX21_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidB/LrgB family autolysis modulator"
                     /protein_id="HDV1987609.1"
                     /translation="MMANIWWSLPLTLIVFFAARKLAARYKFPLLNPLLVAMVVIIPF
                     LMLTGISYDSYFKGSEVLNDLLQPAVVALAYPLYEQLHQIRARWKSIITICFIGSVVA
                     MVTGTSVALLMGASPEIAASILPKSVTTPIAMAVGGSIGGIPAISAVCVIFVGILGAV
                     FGHTLLNAMRIRTKAARGLAMGTASHALGTARCAELDYQEGAFSSLALVLCGIITSLI
                     APFLFPIILAVMG"
     gene            complement(2790..3188)
                     /locus_tag="RHX21_002443"
     CDS             complement(2790..3188)
                     /locus_tag="RHX21_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HDV1987610.1"
                     /translation="MSKTLNIIWQYLRAFVLIYACLYAGIFIASLLPVTIPGSIIGML
                     ILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAV
                     STLVVFLVVSWSSQLVHGERKVVGQKGSEE"
     gene            3427..4374
                     /gene="dusC"
                     /locus_tag="RHX21_002444"
     CDS             3427..4374
                     /gene="dusC"
                     /locus_tag="RHX21_002444"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine(16) synthase DusC"
                     /protein_id="HDV1987611.1"
                     /translation="MRVLLAPMEGVLDSLVRELLTEVNDYDLCITEFVRVVDQLLPVK
                     VFHRICPELQNASRTPSGTLVRVQLLGQFPQWLAENAARAVELGSWGVDLNCGCPSKT
                     VNGSGGGATLLKDPELIYQGAKAMREAVPAHLPVSVKVRLGWDSGEKKFEIADAVQQA
                     GATELVVHGRTKEQGYRAEHIDWQAIGEIRQRLNIPVIANGEIWDWQSAQQCIAISGC
                     DAVMIGRGALNIPNLSRVVKYNEPRMPWPEVVALLQKYTRLEKQGDTGLYHVARIKQW
                     LSYLRKEYDEATELFQHVRVLNNSPDIARAIQAIDIEKL"
     gene            complement(4744..4827)
                     /gene="yohP"
                     /locus_tag="RHX21_002445"
     CDS             complement(4744..4827)
                     /gene="yohP"
                     /locus_tag="RHX21_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YohP"
                     /protein_id="HDV1987612.1"
                     /translation="MKIILWAVLIIFLIGLLVVTGVFKMIF"
     gene            5051..6487
                     /gene="mdtQ"
                     /locus_tag="RHX21_002446"
     CDS             5051..6487
                     /gene="mdtQ"
                     /locus_tag="RHX21_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001583680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug resistance outer membrane protein
                     MdtQ"
                     /protein_id="HDV1987613.1"
                     /translation="MNRDSFYPAIACFPLLLMLAGCAPMHETRQALSQQTPAAQVDTA
                     LPTALKNGWPDSQWWLEYHDNQLTSLINNALQNAPDMQVAEQRIQLAEAQAKAIATQD
                     GPQIDFSADMERQKMSAEGLMGPFALNDPAAGTTGPWYTNGTFGLTAGWHLDIWGKNR
                     AEVTARLGTVKARAAEREQTRQLLAGSVARLYWEWQTQAALNTVLQQIEKEQNTIIAT
                     DRQLYQNGITSSVEGVETDINASKTRQQLNDVAGKMKIIEARLSALTNNQTKSLKLKP
                     VALPKVASQLPDELGYSLLARRADLQAAHWYVESSLSTIDAAKAAFYPDINLMAFLQQ
                     DALHLSDLFRHSAQQMGVTAGLTLPIFDSGRLNANLDIAKAESNLSIASYNKAVVEAV
                     NDVARAASQVQTLAEKNQHQAQIERDALRVVGLAQARFNAGIIAGSRVSEARIPALRE
                     RANGLLLQGQWLDASIQLTGALGGGYKR"
     gene            6540..7301
                     /locus_tag="RHX21_002447"
     CDS             6540..7301
                     /locus_tag="RHX21_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDV1987614.1"
                     /translation="MAQVAIITASDSGIGKECALLLAQQGVDIGITWHSDEEGAKDTA
                     REVVSHGVRAEIVQLDLGKLPEGAQALEKLIQRLGRIDVLVNNAGAMTKAPFLDMAFD
                     EWRKIFTVDVDGAFLCSQIAARQMVKQGQGGRIINITSVHEHTPLPDASAYTAAKHAL
                     GGLTKTMALELVRHKILVNAVAPGAIATPMNGMDDSDVKPDAEPSIPLRRFGATHEIA
                     SLVAWLCSEGANYTTGQSLIVDGGFMLANPQFNPE"
     gene            complement(7431..8009)
                     /locus_tag="RHX21_002448"
     CDS             complement(7431..8009)
                     /locus_tag="RHX21_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416640.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDV1987615.1"
                     /translation="MDLNTLISQYGYAALVIGSLAEGETVTLLGGVAAHQGLLKFPLV
                     VLSVALGGMIGDQVLYLCGRRFGGKLLRRFSKHQDKIERAQKLIQRHPYLFVIGTRFM
                     YGFRVIGPTLIGASQLPPKIFLPLNILGAFAWALIFTTIGYAGGQVIAPWLHNLDQHL
                     KHWVWLILVVVLVVGVRWWLKRRGKKKPDHQA"
     gene            8179..8766
                     /locus_tag="RHX21_002449"
     CDS             8179..8766
                     /locus_tag="RHX21_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014170891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIP1 family protein"
                     /protein_id="HDV1987616.1"
                     /translation="MSHVWGLFSHPDREMQVINRENETISHHYTHHVLLMAAIPVICA
                     FIGTTQIGWNFGDGTILKLSWFTGLALAVLFYGVMLAGVAVMGRVIWWMARNYPQRPS
                     LAHCMVFAGYVATPLFLSGLVALYPLVWLCALVGTVALFYTGYLLYLGIPSFLNINKE
                     EGLSFSSSTLAIGVLVLEVLLALTVILWGYGYRLF"
     gene            8940..9872
                     /gene="pbpG"
                     /locus_tag="RHX21_002450"
     CDS             8940..9872
                     /gene="pbpG"
                     /locus_tag="RHX21_002450"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311048.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine endopeptidase"
                     /protein_id="HDV1987617.1"
                     /translation="MPKFRVSLFSLALMLAVPLAPQAVAKTAAATTASQPEIASGSAM
                     IVDLNTNKVIYSNHPDLVRPIASISKLMTAMVVLDARLPLDEKLKVDISQTPEMKGVY
                     SRVRLNSEISRKDMLLLALMSSENRAAASLAHHYPGGYKAFIKAMNAKAKSLGMNNTR
                     FVEPTGLSVHNVSTARDLTKLLIASKQYPLIGQLSTTREDMATFSNPTYTLPFRNTNH
                     LVYRDNWNIQLTKTGFTNAAGHCLVMRTVINNKPVALVVMDAFGKYTHFADASRLRTW
                     IETGKVMPVPAAALSYKKQKAAQMAAAGQTAQND"
     gene            complement(9911..11626)
                     /gene="dld"
                     /locus_tag="RHX21_002451"
     CDS             complement(9911..11626)
                     /gene="dld"
                     /locus_tag="RHX21_002451"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HDV1987618.1"
                     /translation="MSSMTTTDNKAFLNELARLVGHSHLLTDPAKTARYRKGFRSGQG
                     DALAVVFPGSLLELWRVLKACVTADKIILMQAANTGLTEGSTPNGNDYDRDIVIISTL
                     RLDKLHVLGKGEQVLAYPGTTLYSLEKALKPLGREPHSVIGSSCIGASVIGGICNNSG
                     GSLVQRGPAYTEMSLFARINEDGKLTLVNHLGIDLGETPEQILSKLDDDRIKDDDVRH
                     DGRHAHDYDYVHRVRDIEADTPARYNADPDRLFESSGCAGKLAVFAVRLDTFEAEKNQ
                     QVFYIGTNQPEVLTEIRRHILANFENLPVAGEYMHRDIYDIAEKYGKDTFLMIDKLGT
                     DKMPFFFNLKGRTDAMLEKVKFFRPHFTDRAMQKFGHLFPSHLPPRMKNWRDKYEHHL
                     LLKMAGDGVGEAKSWLVDYFKQAEGDFFVCTPEEGSKAFLHRFAAAGAAIRYQAVHSD
                     EVEDILALDIALRRNDTEWYEHLPPEIDSQLVHKLYYGHFMCYVFHQDYIVKKGVDVH
                     ALKEQMLELLQQRGAQYPAEHNVGHLYKAPETLQKFYRENDPTNSMNPGIGKTSKRKN
                     WQEVE"
     gene            11822..14119
                     /gene="bglX"
                     /locus_tag="RHX21_002452"
     CDS             11822..14119
                     /gene="bglX"
                     /locus_tag="RHX21_002452"
                     /EC_number="3.2.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucosidase BglX"
                     /protein_id="HDV1987619.1"
                     /translation="MKWLCSVGIAVSLALQPALADDLFGNHPLTPEARDAFVTELLKK
                     MTVDEKIGQLRLISVGPDNPKEAIREMIKDGQVGAIFNTVTRQDIRAMQDQVMELSRL
                     KIPLFFAYDVLHGQRTVFPISLGLASSFNLDAVKTVGRVSAYEAADDGLNMTWAPMVD
                     VSRDPRWGRASEGFGEDTYLTSTMGKTMVEAMQGKSPADRYSVMTSVKHFAAYGAVEG
                     GKEYNTVDMSPQRLFNDYMPPYKAGLDAGSGAVMVALNSLNGTPATSDSWLLKDVLRD
                     QWGFKGITVSDHGAIKELIKHGTAADPEDAVRVALKSGINMSMSDEYYSKYLPGLIKS
                     GKVTMEELDDAARHVLNVKYDMGLFNDPYSHLGPKESDPVDTNAESRLHRKEAREVAR
                     ESLVLLKNRLETLPLKKSATIAVVGPLADSKRDVMGSWSAAGVADQSVTVLTGIKNSV
                     GENGKVLYAKGANVTSDKGIIDFLNQYEEAVKVDPRSPQEMIDEAVQTAKQSDVVVAV
                     VGEAQGMAHEASSRTDITIPQSQRDLIAALKATGKPLVLVLMNGRPLALVKEDQQADA
                     ILETWFAGTEGGNAIADVLFGDYNPSGKLPMSFPRSVGQIPVYYSHLNTGRPYNADKP
                     NKYTSRYFDEANGALYPFGYGLSYTTFTVSDVKLSAPTMKRDGKVTASVQVTNTGKRE
                     GATVVQMYLQDVTASMSRPVKQLKGFEKITLKPGETQTVSFPIDIEALKFWNQQMKYD
                     AEPGKFNVFIGTDSARVKKGEFELL"
     gene            14330..15247
                     /gene="osmF"
                     /locus_tag="RHX21_002453"
     CDS             14330..15247
                     /gene="osmF"
                     /locus_tag="RHX21_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter
                     substrate-binding protein OsmF"
                     /protein_id="HDV1987620.1"
                     /translation="MPLLKLWAGSLVMLAAVSLPLQAASPVKVGSKIDTEGALLGNII
                     LQVLESHGVPTVNKVQLGTTPVVRGAITSGELDIYPEYTGNGAFFFKDENDAAWKNAQ
                     QGYEKVKKLDSEHNKLIWLTPAPANNTWTIAVRQDVAEKNKLTSLADLSRYLQEGGTF
                     KLAASAEFIERADALPAFEKAYGFKLGQDQLLSLAGGDTAVTIKAAAQQTSGVNAAMA
                     YGTDGPVAALGLQTLSDPQGVQPIYAPAPVVRESVLKEYPQMAQWLQPVFASLDAKTL
                     QQLNASIAVEGLDAKKVAADYLKQKGWTK"
     gene            15254..16411
                     /gene="yehY"
                     /locus_tag="RHX21_002454"
     CDS             15254..16411
                     /gene="yehY"
                     /locus_tag="RHX21_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter permease YehY"
                     /protein_id="HDV1987621.1"
                     /translation="MTYFRINPVLALLLLLTAIAAALPFISYAPNRLVSGEGRHLWQL
                     WPQTIWMLVGVGCAWLTACFIPGKKGSICALILAQFVFVLLVWGAGKAATQLAQNGSA
                     LARTSLGSGFWLAAALALLACSDAIRRISTHPLWRWLLHMQIAIIPLWLLYSGTLNDL
                     SLMKEYANRQDVFDDALAQHLTLLFGAVLPALVIGVPLGIWCYFSTARQGAIFSLLNV
                     IQTVPSVALFGLLIAPLAALVTAFPWLGKLGIAGTGMTPALIALVLYALLPLVRGVVV
                     GLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVVMVQTVGMAVIAALIG
                     AGGFGALVFQGLLSSAIDLVLLGVIPVIVLAVLTDALFDLLIALLKVKRND"
     gene            16404..17330
                     /gene="yehX"
                     /locus_tag="RHX21_002455"
     CDS             16404..17330
                     /gene="yehX"
                     /locus_tag="RHX21_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter ATP binding
                     protein YehX"
                     /protein_id="HDV1987622.1"
                     /translation="MIEFSHVSKLFGAQKAVNDLNLNFQEGSFSVLIGTSGSGKSTTL
                     KMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQSIGLFPHWSVAQNIATVPQL
                     QKWSRARIDDRIDELMALLGLESNLRERYPHQLSGGQQQRVGVARALAADPQVLLMDE
                     PFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDHGEVVQQGN
                     PLTMLTRPANDFVRQFFGRSELGVRLLSLRSVADYVRREERAEGEALAEEMTLRDALS
                     LFVARGCEVLPVVNTQGQPCGTLHFQDLLEEA"
     gene            17335..18066
                     /gene="yehW"
                     /locus_tag="RHX21_002456"
     CDS             17335..18066
                     /gene="yehW"
                     /locus_tag="RHX21_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter permease YehW"
                     /protein_id="HDV1987623.1"
                     /translation="MKMLRDPLFWLIALFVALIFWLPYSQPLFAALFPQLPRPVYQQE
                     SFAALALAHFWLVGISSLFAVIIGTGAGIAVTRPWGAEFRPLVETIAAVGQTFPPVAV
                     LAIAVPVIGFGLQPAIIALILYGVLPVLQATLAGLGAIDASVTEVAKGMGMSRGQRLR
                     KVELPLAAPVILAGVRTSVIINIGTATIASTVGASTLGTPIIIGLSGFNTAYVIQGAL
                     LVALAAIIADRLFERLVQALSQHAK"
     gene            complement(18047..18154)
                     /locus_tag="RHX21_002457"
     CDS             complement(18047..18154)
                     /locus_tag="RHX21_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YohO"
                     /protein_id="HDV1987624.1"
                     /translation="MRIAKIGVIALFLFMALGGIGGVMLAGYTFILRAG"
     gene            complement(18214..18945)
                     /gene="mlrA"
                     /locus_tag="RHX21_002458"
     CDS             complement(18214..18945)
                     /gene="mlrA"
                     /locus_tag="RHX21_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MlrA"
                     /protein_id="HDV1987625.1"
                     /translation="MALYTIGEVALLCDINPVTLRAWQRRYGLLKPQRTDGGHRLFND
                     ADIDRIREIKRWIDNGVQVSKVKMLLSNENVDVQNGWRDQQETLLTYLQSGNLHSLRT
                     WIKERGQDYPAQTLTTHLFIPLRRRLQCQQPTLQALLAILDGVLINYIAICLASARKK
                     QGKDALVVGWNIQDTTRLWLEGWIASQQGWRIDVLAHSLNQLRPELFEGRTLLVWCGE
                     NRTSAQQQQLTSWQEQGHDIFPLGI"
     gene            19167..20852
                     /gene="btsS"
                     /locus_tag="RHX21_002459"
     CDS             19167..20852
                     /gene="btsS"
                     /locus_tag="RHX21_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component regulatory system sensor histidine
                     kinase BtsS"
                     /protein_id="HDV1987626.1"
                     /translation="MYDFNLVLLLLQQMCVFLVIAWLMSKTPLFIPLMQVTVRLPHKF
                     LCYIVFSIFCIMGTWFGLHIDDSIANTRAIGAVMGGLLGGPVVGGLVGLTGGLHRYSM
                     GGMTALSCMISTIVEGLLGGLVHSILIRRGRTDKVFNPITAGAVTFVAEMVQMLIILA
                     IARPYEDAVRLVSNIAAPMMVTNTVGAALFMRILLDKRAMFEKYTSAFSATALKVAAS
                     TEGILRQGFNEVNSMKVAQVLYQELDIGAVAITDREKLLAFTGIGDDHHLPGKPISST
                     YTLKAIETGEVVYADGNEVPYRCSLHPQCKLGSTLVIPLRGENQRVMGTIKLYEAKNR
                     LFSSINRTLGEGIAQLLSAQILAGQYERQKAMLTQSEIKLLHAQVNPHFLFNALNTIK
                     AVIRRDSEQASQLVQYLSTFFRKNLKRPSEFVTLADEIEHVNAYLQIEKARFQSRLQV
                     NIAIPQELSQQQLPAFTLQPIVENAIKHGTSQLLDTGRVAISARREGQHLMLEIEDNA
                     GLYQPVTNASGLGMNLVDKRLRERFGDDYGISVACEPDSYTRITLRLPWRDEA"
     gene            20849..21568
                     /gene="yehT"
                     /locus_tag="RHX21_002460"
     CDS             20849..21568
                     /gene="yehT"
                     /locus_tag="RHX21_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310963.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BtsR"
                     /protein_id="HDV1987627.1"
                     /translation="MIKVLIVDDEPLARENLRVFLQEQSDIEIVGECSNAVEGIGAVH
                     KLRPDVLFLDIQMPRISGLEMVGMLDPEHRPYIVFLTAFDEYAIKAFEEHAFDYLLKP
                     IDEARLEKTLARLRQERSKQDVSLLPENQQALKFIPCTGHSRIYLLQMKDVAFVSSRM
                     SGVYVTSHEGKEGFTELTLRTLESRTPLLRCHRQYLVNLAHLQEIRLEDNGQAELILR
                     NGLTVPVSRRYLKSLKEAIGL"
     gene            21615..22085
                     /locus_tag="RHX21_002461"
     CDS             21615..22085
                     /locus_tag="RHX21_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HDV1987628.1"
                     /translation="MLSNDILRSVRYILKANNNDLVRILALGNVEATAEQIAVWLRKE
                     DEEGFQRCPDIVLSSFLNGLIYEKRGKDESAPPLEPERRINNNIVLKKLRIAFSLKTD
                     DILAILTEQQFRVSMPEITAMMRAPDHKNFRECGDQFLRYFLRGLAARQHVKKG"
     gene            complement(22125..22586)
                     /locus_tag="RHX21_002462"
     CDS             complement(22125..22586)
                     /locus_tag="RHX21_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416627.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YehR family lipoprotein"
                     /protein_id="HDV1987629.1"
                     /translation="MKAFNKLFSLVVASVLVFSLAGCGDKEESKKFSANLNGTEIAIT
                     YVYKGDKVLKQSSETKIQFASIGATTKEDAAKTLEPLSAKYKNIAGVEEKLTYTDTYA
                     QENVTIDMEKVDFKALQGISGINVSAEDAKKGITMAQMELVMKAAGFKEVK"
     gene            complement(22711..24711)
                     /locus_tag="RHX21_002463"
     CDS             complement(22711..24711)
                     /locus_tag="RHX21_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HDV1987630.1"
                     /translation="MNSLRPELLELTPQALTALSNAGFVKRSLKELENGNVPEISHEN
                     GALIATFSDGVRTQLANSQALKEAQCSCGASGMCRHRVMLVLSYQRLCATVQPTEKEE
                     EWDPAIWLEELATLPDATRKRAQALVAKGITIELFCAPGEIPSARLPMSDVRFYSRSS
                     IRFARCDCIEGTLCEHVVLAVQAFVEAKAQQAEFNHLIWQMRSEHVTSSDDPFASEEG
                     QTCRQYVQQLSQALWLGGISQPLIHYEAAFNRALQAAEACNWRWVSESLRQLRASVDA
                     FHTRASHYHAGECLRQLAALNSRLNCAQEMARRDSVGEVPPVPWRTVVGSGIAGEAKL
                     DHLRLVSLGMRCWQDIEHYGLRIWFTDPDTGSILHLSRSWPRSEQENSPAATRRLFSF
                     QAGALAGGQIVSQAAKRSADGELLLATRNRLSSVVPLSPDAWQMLSAPLRQPGIVALR
                     EYLRQRPPACIRPLNQVDNLFILPVAECISLGWDSSRQTLDAQVISGEGEDNLLTLSL
                     PASACSPFAVERMAALLQQTDDPVSLVSGFVSFVDGQLTLEPRVMMTKTRAWALDAET
                     APVAPLPSASVLPVPSTAHQLLMRCQALLIQLLHNGWRYQEQSAISQAELLANDLSAV
                     GFYRLAHVLGQFRNTESEARVEAMNNGVLLCEQLFPMLQQQG"
     gene            complement(24708..25844)
                     /locus_tag="RHX21_002464"
     CDS             complement(24708..25844)
                     /locus_tag="RHX21_002464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDV1987631.1"
                     /translation="MSELNDLLTTRELQRWRLILGEAAETTLCGLDDNARQIDHALEW
                     LYGRDPERLQRGERSGGLGGSNLTTPEWINSIHTLFPQQVIERLESDAVLRYGIEDVV
                     TNLDVLERMQPSESLLRAVLHTKHLMNPEVLAAARQIVRQVVEEIMARLAKEVRQAFS
                     GVRDRRRRSLIPLARNFDFKSTLRANLQHWHPQHGKLYIESPRFNSRIKRQSEQWQLV
                     LLVDQSGSMVDSVIHSAVMAACLWQLPGIRTHLVAFDTSVVDLTADVADPVELLMKVQ
                     LGGGTNIASAVEYGRQLIEQPAKSVIILVSDFYEGGSSSLLTHQVKKCVQSGIKVLGL
                     AALDSTATPCYDRDTAQALVNVGAQIAAMTPGELASWLAENLQS"
     gene            complement(25837..28117)
                     /locus_tag="RHX21_002465"
                     /pseudo
     CDS             complement(25837..28117)
                     /locus_tag="RHX21_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416624.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(28128..29216)
                     /locus_tag="RHX21_002466"
     CDS             complement(28128..29216)
                     /locus_tag="RHX21_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310954.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HDV1987632.1"
                     /translation="MSPQNNHLQRPPAAVLYADELAKLKQNDNAPCPPGWQLSLPAAR
                     AFILGDSAQNISRKVVISPSAVERMLVTLATGRGLMLVGEPSTAKSLLSELLATAISG
                     DAGLTIQGGASTTEDQIKYGWNYALLINHGPSTEALVPAPLYQGMRDGKIVRFEEITR
                     TPLEVQDCLLGMLSDRVMTVPELTGEASQLYAREGFNIIATANTRDRGVNEMSAALKR
                     RFDFETVFPIMDFAQELELVASASARLLAHSGIPHKVPDAVLELLVRTFRDLRANGEK
                     KTSMDTLTAIMSTAEAVNVAHAVGVRAWFLANRAGEPADLVDCIAGTIVKDNEEDRAR
                     LRRYFEQRVATHKEAHWQAYYQARHRLP"
BASE COUNT         7022 a         7536 c         7993 g         6946 t
ORIGIN      
        1 atgccgatag ataaaattcc gaagccgata tatgccacca tataagcgaa aaagagtccg
       61 ggattttttg ctcgccagac atacaccggt tccggtgcat ttttaacccg tttatcaatc
      121 gcgcctgcgc gccagccttt ccatgcttcg cggaaacaaa atatcggaat aaggaaaaaa
      181 acggcaacga caaaaaactg ctgtacatcc ataactactt tccttgtttc ttttgtaatt
      241 caagtaactg ttcgggtgtg acggcgggat acccctgcgc atcttccggc acctggtgca
      301 tagccggaat agggaccagc ggccctaaaa aacgcggttc acgtttaaaa atataaaggt
      361 cagccagcgc accgaaacgg gcggcaaatt cgcgaatacg tactgacagc atatctttcg
      421 gtgacggtac ggcataacac tgagcctgaa tccccatatg cagcgcaata aataatgccc
      481 gctcacagtg gaaacgttgg gtgataataa tgaaatcatt agtatcgaaa actttgcgtg
      541 tacgcacgat ggaatccagc gtacgaaagc ctgcgtaatc gagaacaata tctgatgggt
      601 cgacaccagc agcgattaaa tctttgcgca tagtcatcgg ctcattataa ctttgcaatg
      661 cgttatcgcc gctcagtaat agataattta ccttaccgct gttataggca ttaatcgctc
      721 cttgaatgcg gtagcgataa tactgattaa ttacgccagt acgataatat tttgctgttc
      781 cgagcaccac accgacctgg cggtagggga gatcctgcaa ttcgtcgtag atataaggcg
      841 cggttttcca gctcatccag cgatcgaggc cgagcacagt caacagcagc aagccgatca
      901 ggactaacag gctgaggaac acgcgcttta acatgcagga gactcgatct aaggaaaatt
      961 tccatcaggc tactttaccc gctggttttg cgcaagaaac ggcaaactgt ttgccgggaa
     1021 tttcgacacc aggagagggc tggcaagccg gacaaggcgt tcacgccgca tccggcacca
     1081 ggcttaagcg agaagcactc ggtcgatact gtgacagccg agagctttca gcgttgcgga
     1141 ggtggcatcc cactgaatca acggcgcatc ggcgttttct gccagaaccg cgcgctggat
     1201 atccgggtaa tcataaccct tgagattcaa tagaattaac gctccctgca acggtggcag
     1261 agtcgggttg aatgcggcgt tttcagcgta gctgccgctg aaaatacgac cgtctttaca
     1321 ttccagcgcg acaccgcttg gcgacttact gtaaggcatg tgcgaacggt ttgccgctgc
     1381 aatcgccgcc tgagaaagcg catcaccagt cagcgcatag ccgtgatcct gctcgtccat
     1441 cagcagcgtt ttaatctcca gatctttcgg cccaaaggca tccggcagat agtcacgcag
     1501 cgcgtgtgcc tcgcggcccg gcagatgaat acgcagatcc agaccgctgt tcagttcatt
     1561 cataaactga cggcagtgac cacaaggcgt gtagttaacg gtgatggctg caagcgcttt
     1621 ttcaccactc aaccaggcgt ggctgatcgc gctttgttcg gcatgaacgg tttgctgcat
     1681 tgtcgcacca ataaattcca tattggcacc gaaataccag gttccgctca caccgcgcgc
     1741 aattgcgcca acattaaaat tcgacaatgg cgtacgcgca caggccgccg ccagcggaag
     1801 tagtgcgaat gccagcgcgt cttcgtccag ccccgttgcg ctcttcagcg atgagacttg
     1861 ctccccggtc aacaaagcgg ggaagtactt gtctgccaga ataggttcca gtgcagattg
     1921 caagttatcc gcaagttggg caaaagcggt ttgaaaacgt ggatgcatgg cgttgcctca
     1981 taatcatgta atgggataac agtttacgaa cccgttatgg ctttatatgt gatctgaatc
     2041 tcattaatta tgcaacgcgt gaaacttaca tcaaaaatgc gcgacgcatc gcaaatttta
     2101 gcccattact gccagaataa tcgggaaaag gaacggtgcg atcagcgaag taattatccc
     2161 gcataacacc agcgctagcg aactaaatgc accttcctga taatccagct cggcgcagcg
     2221 cgccgtaccg agggcgtgcg aggcagtccc cattgccaga ccgcgcgcag ctttggtacg
     2281 aatacgcatc gcattaagca atgtatggcc aaataccgcg ccgaggatgc cgacgaaaat
     2341 cacgcaaact gcgctgattg ccggaatacc gccaatactg ccgccaaccg ccattgcaat
     2401 aggcgtggtg actgatttcg gcaggattga cgcggcgatt tccggtgaag cgcccatcaa
     2461 caatgccacg gaagtccccg tcaccatcgc aaccacgctg ccgataaaac agatggtgat
     2521 gatcgatttc cagcgcgcgc ggatctggtg tagctgctca tataaaggat aagccaacgc
     2581 gacaaccgcc ggttgcagca aatcgtttag cacttcgcta cctttaaagt agctgtcgta
     2641 agagatgccg gtgagcatta aaaaaggaat gatcaccacc attgctacca gcaacgggtt
     2701 aagcaggggg aacttatacc gtgccgccag tttgcgggcg gcaaaaaaga caatcaacgt
     2761 cagcggtaat gaccaccaga tattcgccat cattcttctg atcctttctg acctacgact
     2821 ttacgttcac cgtgtaccag ttgtgaactc cagctcacca ccagaaaaac caccagcgta
     2881 ctgactgcac aggaaaccac taccgggcca aactgtgcgc ggagcaaatc aaaatattgc
     2941 atgacgccta cgccaatcgg cacaaacaat agcgccatat agcgaatcag tacgtagcac
     3001 cccggattga cccattttgc cggaagaatt tgcaaggcca gcaggacaaa caggatcagc
     3061 ataccgatga tgctgcccgg aatggttacc ggtagcaggg aagcaatgaa aatgcctgca
     3121 tacaggcagg cataaatcag gacgaaagcg cgtaaatatt gccagataat gttcagtgtc
     3181 ttactcataa tcaacacccc agatgagatg gattcatcat acaattaatt cgtaaaacgt
     3241 gctaccgatc acattaagaa atcagcgctt attttttcgc tccccggcat tacgcaatgc
     3301 gcaacgaact caggcataca tcaagcatag agagggatta cagtttgcag caatccctct
     3361 ttgcagacct ttaatccgtt gaccataggc gctaacatgg cgcctcattt ttttgcgggt
     3421 gaagatatgc gtgtgttact ggctccgatg gagggtgtgc ttgactctct ggtgcgtgaa
     3481 ttgctgaccg aagttaacga ctacgatctg tgcatcaccg agtttgtccg cgtggtggat
     3541 caactgctgc cggtaaaagt ctttcatcgc atttgccctg agctacaaaa cgccagccgg
     3601 acaccatctg gtacgctggt gcgcgtgcag ttgttaggtc agttcccaca atggctggca
     3661 gagaacgccg cccgtgcggt ggagttaggt tcctggggcg tggatctcaa ttgcggctgc
     3721 ccgtcgaaaa cggttaacgg tagcggcggc ggcgcgacgt tactcaaaga tcctgaactc
     3781 atctaccagg gtgcaaaagc gatgcgtgaa gctgtaccag cgcatttgcc cgtcagcgta
     3841 aaagtgcgtc tgggctggga cagcggtgag aagaaatttg aaatcgccga tgcggttcaa
     3901 caggctggcg ctacggagct ggtggtgcat ggacggacaa aagagcaggg ttaccgcgcg
     3961 gagcatattg actggcaggc gattggcgag attcgccagc ggctgaatat tccggtgatt
     4021 gccaacggcg aaatctggga ctggcagagc gcgcaacaat gcattgcgat cagcggctgc
     4081 gacgcagtga tgattggtcg cggggcgctc aatattccca acctgagccg ggtagtaaaa
     4141 tataacgaac cgcgaatgcc gtggccggag gtggttgctt tgctgcaaaa atatacccgt
     4201 ctggaaaagc agggcgatac cgggttatat cacgttgcgc ggattaaaca gtggttgagt
     4261 tatttgcgta aagaatacga tgaagcaacg gaattatttc agcatgttcg ggtgttgaat
     4321 aattcccctg atattgcaag ggctattcag gcaattgata tcgagaaact ctaaaaaacc
     4381 atagtgatgt tttttgacaa tgtgttagct ctttatcaat aggccgcacg gttgtttggt
     4441 ggcgtcaaaa ttgccgaggc gttccctgaa ggccggggca gcccacatgg atgtgggctg
     4501 agggcgcgtt ttacagggat gttacctcgc gcccgacccg gtagccgtaa gggataagcc
     4561 gagggcaccg cgcagcggcg attttgttcg ccagagcccg ggggggcagg ggcggcggcg
     4621 attggccgcc ctgcgcgctc cttgcgccag tgattatatg aagcaatgca catgacagga
     4681 gcgcaacagg atgagagact gaaatattct cgttattttc ggacctgatg acattaatta
     4741 attttaaaat atcatcttaa atacgccagt caccaccagt agcccaatca ggaaaataat
     4801 caatacagcc cagagtataa ttttcattgg cgttccttta tttgtgagtg ctgaataagt
     4861 ataggaaaaa acgaagccct ttgccgttat ccataaacga ttaagataaa tcggaagata
     4921 tcatttactt agtctatatt tttctggata tgtcgtttta ttgctactga tgtattgcca
     4981 cgcgaaacta aaaaatatat cgcaacacac ggtaatctcc gcgcaccttt tcttacctga
     5041 ttattccccc atgaatcgtg attcctttta tccagccatc gcctgttttc cgctgttact
     5101 gatgctggcc gggtgtgcac ctatgcatga aacccgccag gcgttaagcc agcaaacgcc
     5161 tgctgcacaa gttgacaccg cattacccac ggcgctgaaa aatggttggc cagacagcca
     5221 atggtggctg gagtatcacg ataatcaact cacttcctta attaacaatg cactacagaa
     5281 cgcaccggat atgcaggtgg ctgaacagcg cattcagcta gctgaagccc aggcgaaggc
     5341 aattgctact caggatggtc cgcagatcga cttttctgcg gatatggagc ggcaaaaaat
     5401 gtcggcagaa ggcttaatgg ggccgtttgc tctgaacgat ccggccgcag gtacgaccgg
     5461 tccgtggtac accaacggaa cttttggctt aacggcgggc tggcatctcg atatctgggg
     5521 aaagaatcgg gcggaggtta ctgcccgcct gggtacggtt aaagcacggg cggcggaacg
     5581 cgagcaaacc cgccaattgc tggctggcag cgtagcccgc ctgtactggg agtggcaaac
     5641 ccaggcggcg ttaaacacgg tcttgcagca aatagaaaaa gagcagaaca ccattatcgc
     5701 gaccgatcgc cagctatatc agaacgggat tacttcttca gttgaaggtg tggaaaccga
     5761 tattaatgcc agcaaaaccc ggcagcagct caacgatgtc gcggggaaaa tgaaaattat
     5821 tgaggcacgg ttaagcgcac ttacaaataa ccagacaaag tcattgaagc ttaaaccggt
     5881 cgcgttgccg aaagtggcaa gccagcttcc tgatgaactg gggtactcct tactggcccg
     5941 gcgggcagat ttgcaggcgg cgcactggta cgttgagtca tcgctaagca ccattgatgc
     6001 ggcaaaagcg gcattttatc ctgacatcaa cctgatggcc ttcctgcaac aggatgcgtt
     6061 gcacttaagc gatctgttcc gtcattccgc gcagcaaatg ggcgttacgg caggcctgac
     6121 gctacccatt ttcgatagtg gtcgtcttaa cgccaatctc gatatcgcaa aagccgaaag
     6181 caacttgtct atcgccagct acaacaaagc ggtggttgaa gcggtgaatg acgtggcgcg
     6241 ggcagccagt caggttcaga cacttgcgga gaaaaaccag catcaggcgc aaattgagcg
     6301 cgatgccttg cgtgtggtag gtcttgcgca ggcgcgcttt aacgcgggca tcattgctgg
     6361 ttcccgcgtc agcgaagcca gaatccccgc gctgcgtgag cgggccaatg gcctgttatt
     6421 gcaagggcag tggctggatg cttccattca actcactggt gcgttgggcg ggggttacaa
     6481 acgctgatga tatgcgcctt ctatacttaa cgtttattca gcgttaagtg gagaactcga
     6541 tggcacaggt tgcgattatt accgcctccg attcggggat cggcaaagag tgcgcgttat
     6601 tactggcgca gcagggggtt gatattggca ttacctggca ctcagatgaa gaaggggcaa
     6661 aagataccgc gcgtgaggta gttagccacg gcgtacgtgc ggagatcgtg cagctggatc
     6721 tcggtaaact gccagaaggt gcgcaggcgc tggagaaact cattcaacgg ctggggcgta
     6781 ttgatgtgct ggtgaataat gcgggcgcaa tgaccaaagc gccgtttctt gatatggctt
     6841 ttgatgagtg gcgcaagatt tttaccgttg atgttgatgg tgcattttta tgctcgcaaa
     6901 ttgcggcccg ccagatggtg aaacaagggc agggcggtcg catcatcaac attacgtcgg
     6961 tacatgaaca tacgccgctg ccggatgcca gcgcttacac agccgctaaa catgcgctcg
     7021 gcgggttaac caaaacgatg gcgctggagc tggtcaggca taagattttg gtgaacgcag
     7081 tcgcgcctgg ggcgatcgcc acgccaatga atggcatgga tgacagcgac gtgaagcccg
     7141 acgcggagcc ttcgattcct ctgcggcgtt ttggcgcaac gcatgagatt gccagcctgg
     7201 tagcgtggct gtgctcagag ggcgcaaatt acaccaccgg gcagtcgttg atagtggatg
     7261 gcggctttat gttggcgaat ccgcagttca acccagaata gcgcagtgag gtgcgtggtt
     7321 atttcaatgg gtaaaatttt ggtaggcatg ataagacgca caagcgtcgc atcaggcatg
     7381 gtgcaccgga tgtcggatgc ggcgcgaacg ccttacccag ggcaatggtt ttacgcctga
     7441 tgatccggct ttttcttccc gcgccgtttc agccaccagc gcacgcccac caccagaacc
     7501 acgaccagaa tcaaccagac ccagtgcttc aaatgctggt cgagattgtg caaccacggc
     7561 gcaatcacct gaccaccagc gtaaccaata gtggtaaaaa tcaacgccca ggcaaatgcg
     7621 ccgagaatat tcagcggcag aaagattttc ggcggcagct ggctggcacc aatcagcgtc
     7681 gggccaatca cccgaaagcc atacataaag cgcgtaccaa tgacaaacag atacggatgg
     7741 cgttggataa gtttctgcgc ccgctcaatt ttatcctgat gtttcgagaa acggcgtaac
     7801 agcttgccgc caaaccgccg cccgcacaga tagagcacct ggtcgccaat catgccgcca
     7861 agcgccacag aaagtaccac cagcgggaac tttaatagcc cctgatgcgc cgcaacgcct
     7921 cccagcaaag tcacggtttc accttccgcc aggctaccga tcaccagcgc ggcataacca
     7981 tattgtgaga taagtgtatt gagatccata ggccagtctg tctccctttg gttgccagta
     8041 agcatacacc ctgtgaatca ttcacgctga aaaaggacgt tcatcagaca gtgaaaatta
     8101 catgagcgaa caaaaaataa tcacaagctg acttatactt gaactgtcag gttcatgaac
     8161 tcacaacaag ggggcggtat gagccatgtc tggggactgt tttcccatcc cgatcgtgaa
     8221 atgcaggtga ttaatcgcga aaacgaaacg atttctcacc attacaccca ccacgttttg
     8281 ctgatggcgg cgattccggt gatttgcgcc ttcattggca ctacacagat tggctggaat
     8341 tttggcgatg gcactatcct gaagttatcc tggtttaccg gactggcgct ggctgtcttg
     8401 ttttacggcg ttatgctggc tggggtcgcg gtgatggggc gggtcatctg gtggatggcg
     8461 cgcaattacc cgcagcgtcc gtcacttgcg cactgcatgg tcttcgcggg ctacgttgca
     8521 actccgctgt ttttaagcgg tctggtggcg ctttatccgc tggtctggtt gtgtgcgctg
     8581 gtcggcacgg tggcgctgtt ttacaccggc tacctgcttt accttggtat tccgagcttc
     8641 ctgaatatca acaaagagga aggccttagc ttctccagtt cgacgctggc gattggcgtg
     8701 ctggtactgg aagtgctgct cgccctaacc gttatactat ggggctacgg gtatcgcctg
     8761 ttctagaaag ttctttgaca ttgcattgct ggcgtaaatg tcagcaatgc agcatttcct
     8821 cacgattctc ctttgacgat cgcacttttt gctcgttatg atggcgtcgc tagcctcagt
     8881 aaatccttac tccggcggtg cgcaacccgt gcgcgtgaac cactatctga atgctcatca
     8941 tgccgaaatt tcgagtttct ttatttagcc tggccctgat gctggctgtg cctttggcac
     9001 cgcaggccgt tgcgaaaacg gcagccgcta ccaccgcttc acaaccggaa attgcctccg
     9061 gtagcgcgat gattgttgat ctgaatacca acaaagtgat ctattcgaac cacccggatc
     9121 tggtgcgtcc gattgcgtct atcagcaaat taatgaccgc gatggttgtg ctggatgcac
     9181 gactgccgct ggatgaaaaa ctaaaagtgg atatcagcca gacgccggag atgaaagggg
     9241 tctattcgcg cgtacgactg aatagcgaaa tcagccgtaa agatatgctg ttgctggcgc
     9301 tgatgtcttc agaaaaccgc gcggcggcaa gccttgcgca ccattatccc ggtggttaca
     9361 aagcctttat taaggcaatg aatgcgaaag cgaaatcgct cggaatgaac aacacgcgct
     9421 ttgttgaacc taccggattg tcggtgcata acgtttcaac tgcccgtgac ttaaccaaac
     9481 tgctcattgc cagcaaacag tatccgttga tcgggcagtt aagtactacc cgggaagata
     9541 tggcaacctt ctctaacccg acatatacgc tgccgttccg caatactaat catctggtgt
     9601 atcgcgataa ctggaatatt cagttaacca aaaccggctt taccaatgcg gcgggccatt
     9661 gtctggtgat gcgtacggtt atcaataata aaccggtggc gctggtagtg atggacgcgt
     9721 ttggcaaata tacccatttt gccgatgcca gccgcctgcg tacctggatt gaaaccggta
     9781 aagtgatgcc tgtgccggca gcagcgttga gctataaaaa acaaaaagcc gcccaaatgg
     9841 cggcggcggg gcagacggca cagaacgatt aagtgaatga cggatggcga tactctgcca
     9901 tccgtaattt ttactccact tcctgccagt ttttccgttt actggtttta ccgatccccg
     9961 gattcatgct gttggtcgga tcgttctcgc gatagaactt ctgcaacgtc tccggtgctt
    10021 tatacaaatg accgacgtta tgctcggcag ggtattgcgc gccgcgctgc tgtagcagtt
    10081 ccagcatctg ttcttttaac gcatgcacat ccacgccttt tttcactatg taatcctgat
    10141 ggaagacata gcacataaaa tggccgtaat agagcttgtg caccagctgg ctgtcgatct
    10201 ccggcggtaa atgctcatac cactcggtgt cgttacgccg cagagcgata tccaacgcca
    10261 gaatgtcttc gacttcatcg gaatgcaccg cctgataacg aattgctgcg cccgcagcgg
    10321 cgaaacggtg taaaaacgct ttgctgcctt cctccggcgt acagacaaag aaatcgcctt
    10381 cggcctgttt gaaataatcc accaaccacg atttggcttc gcccacgcca tcgcccgcca
    10441 tttttaacag cagatgatgc tcgtatttat cgcgccagtt tttcatgcgc ggcggtaaat
    10501 ggctggggaa caggtgaccg aatttttgca tcgcacggtc agtaaaatgc ggacggaaga
    10561 atttcacttt ctccagcatc gcatcggtgc gtcccttgag attaaagaag aacggcatct
    10621 tgtcggtgcc taacttatca atcatcagga aggtgtcttt gccgtatttt tccgcaatat
    10681 cgtagatatc ccggtgcata tattccccgg caaccggcag attttcgaag ttagccagaa
    10741 tatgacggcg gatttcggtc agcacttccg gctggttggt gccgatataa aacacctgct
    10801 gatttttttc cgcttcgaag gtatctagac gtactgcaaa gaccgccagc ttcccggcgc
    10861 aaccagaaga ttcaaataac cgatcaggat cggcgttata acgtgcgggc gtgtcggctt
    10921 caatatcacg aacgcggtgg acatagtcat aatcgtgggc gtgacgacca tcgtgacgca
    10981 catcgtcatc tttgatgcga tcatcatcca gcttgctaag gatctgctcc ggcgtttcgc
    11041 ccagatcaat ccccagatgg ttcaccagcg tcagtttgcc gtcttcattt atacgcgcga
    11101 ataacgacat ttcggtatac gccgggccac gttgcaccag cgagccgccg gagttgttac
    11161 aaataccgcc gataaccgat gcgcctatac acgacgatcc aatcaccgag tgcggttcgc
    11221 gtcccagcgg tttgagggct ttttccagcg aatagagcgt ggtgcccgga taggccagca
    11281 cctgttcgcc cttgccaaga acgtgcagct tgtcgagacg cagggtgctg atgatcacga
    11341 tatcgcgatc atagtcgtta ccgtttggcg tcgatccttc ggtcaggcct gtattggcag
    11401 cctgcatcag aataattttg tcggcggtga cacaggcttt cagcacccgc cacaattcca
    11461 gtagtgagcc agggaaaacg acagccagcg cgtcgccctg accagaacgg aagcccttgc
    11521 gatagcgggc cgtttttgcg ggatcggtga gcaggtgtga atgaccgacc agacgggcaa
    11581 gttcattcaa aaaggcttta ttatcagttg ttgtcatgga agacattttc cactccttgt
    11641 ggtggcgaaa aaatatcaca aactagaata gcgccttgta tgacaattca gcgagtgaat
    11701 attttgaaaa ttcagacaat aaactgagca ttctttttct ctctccatca tgcttatggc
    11761 aaactacggt ttttgcacca ttttcgctgc ctcgtcgggc aacagaggaa gaaaaatcca
    11821 tatgaaatgg ctatgttcag taggaatcgc ggtgagtctg gccctgcagc cagcactggc
    11881 ggatgattta ttcggcaacc atccattaac gcccgaagcg cgggatgcgt tcgtcaccga
    11941 actgcttaag aaaatgacag ttgatgagaa aattggtcag ctgcgcttaa tcagcgtcgg
    12001 cccggataac ccgaaagagg cgatccgcga gatgatcaaa gacggtcagg ttggggcgat
    12061 tttcaacacc gtaacccgtc aggatatccg cgccatgcag gatcaggtga tggaattaag
    12121 ccgcctgaaa attcctcttt tctttgctta cgacgtgctg cacggtcagc gcacggtgtt
    12181 cccgattagc ctcggtctgg cctcgtcttt taacctcgat gcagtgaaaa cggtcggacg
    12241 tgtctctgct tatgaagcgg cagatgatgg cctgaatatg acctgggcac cgatggtcga
    12301 tgtctcgcgc gatccgcgct ggggacgtgc ttccgaaggt tttggcgaag atacgtatct
    12361 cacctcaaca atgggtaaaa ccatggtgga agcgatgcag ggtaaaagcc cggcagatcg
    12421 ctactcggtg atgaccagcg tcaaacactt tgccgcatac ggcgcggtag aaggcggtaa
    12481 agagtacaac accgtcgata tgagtccgca gcgcctgttt aatgattata tgccgccgta
    12541 caaagcgggg ctggacgcag gcagcggcgc ggtgatggtg gcgctgaact cgctgaacgg
    12601 cacgccagcc acctccgatt cctggctgct gaaagatgtt ctgcgcgacc agtggggctt
    12661 taaaggcatc accgtttccg atcacggtgc aatcaaagag ctgattaaac atggcacggc
    12721 ggcagacccg gaagatgcgg tgcgcgtggc gctgaaatcc ggaatcaaca tgagtatgag
    12781 cgacgagtat tactcgaagt atctgcctgg gttgatcaaa tccggcaaag tgacgatgga
    12841 agagctggac gatgctgccc gccatgtact gaacgttaaa tatgatatgg gattgtttaa
    12901 cgacccatac agccatttgg ggccgaaaga gtctgacccg gtggatacca atgccgaaag
    12961 ccgcctgcac cgtaaagaag cgcgtgaagt ggcgcgcgaa agcctggtgt tgctgaaaaa
    13021 ccgtctcgaa acgttaccgc tgaaaaaatc ggccaccatt gcggtggttg ggccactggc
    13081 ggacagtaaa cgtgacgtga tgggcagctg gtccgcagcc ggtgttgccg atcaatccgt
    13141 gaccgtactg accgggatta aaaattccgt cggtgaaaac ggtaaagtgc tgtatgccaa
    13201 aggggcgaac gttaccagtg acaaaggcat tatcgatttc ctgaatcagt atgaagaagc
    13261 ggtcaaagtc gatccgcgtt cgccgcaaga gatgattgat gaagcggtgc agacggcgaa
    13321 acaatctgat gtggtggtgg ctgtagtcgg tgaagcacag gggatggcgc acgaagcctc
    13381 cagccggacc gatatcacta ttccgcaaag ccaacgtgac ttgattgcgg cgctgaaagc
    13441 caccggtaaa ccgctggtgc tggtgctgat gaacgggcgt ccgctggcgc tggtgaaaga
    13501 agatcagcag gctgatgcga ttctggaaac ctggtttgcg gggactgaag gcggtaatgc
    13561 aattgccgat gtattgtttg gcgattacaa cccgtccggc aagctgccaa tgtccttccc
    13621 gcgttctgtc gggcagatcc cggtgtacta cagccatctg aataccggtc gcccgtataa
    13681 tgccgacaag ccgaacaaat acacttcgcg ttattttgat gaagctaacg gggcgttgta
    13741 tccgttcggc tatgggctga gctacaccac tttcaccgtc tctgatgtga aactttctgc
    13801 gccgaccatg aagcgtgacg gcaaagtgac tgccagcgtg caggtgacga acaccggtaa
    13861 gcgcgagggg gccacggtag tgcagatgta cttgcaggat gtgacggctt ccatgagtcg
    13921 ccctgtgaaa cagctgaaag gctttgagaa aatcaccctg aaaccgggcg aaactcagac
    13981 tgtcagcttc ccgatcgata ttgaggcgct gaagttctgg aatcaacaga tgaaatatga
    14041 cgccgagcct ggcaagttca atgtatttat cggcactgat tccgcacgcg ttaagaaagg
    14101 cgagtttgag ttgctgtaat gctttagtaa gggcgcgacg tttgcgccct ttgtaggccg
    14161 gataaggcgc tcgcgccgca tccggcagga aacgccggac cgaatatgcc tcttaagtat
    14221 ttatctgatt ctgcaactga atccttccgc tcaagctaac cccgccatta tcaactatgc
    14281 ttttctctta attcgctgaa aacaacagta aaagaatgag gaaagcatca tgccactctt
    14341 aaagctctgg gcaggttcac tggttatgtt ggcagccgtg agcctgccgc tacaggcggc
    14401 ttcccccgtt aaagtcggtt caaaaatcga taccgaaggt gcgctactcg gcaatatcat
    14461 tttgcaggtg ctggaaagcc acggcgtacc gacggtgaat aaagtgcaac tcggaacgac
    14521 tcctgtggtg cgcggggcga ttacttccgg tgaactggat atctatccgg aatataccgg
    14581 caatggcgct ttcttcttta aagatgaaaa cgatgcagcg tggaaaaacg cgcagcaagg
    14641 ttacgagaaa gtcaaaaagc tcgattcgga gcacaacaag ttaatctggc tgacgcccgc
    14701 gcctgcaaat aacacctgga ctatcgccgt gcgtcaggat gtggcagaga aaaataaact
    14761 cacttcgctt gccgacctga gtcgttatct gcaagagggc ggcaccttca aactggcagc
    14821 ctcggcagag tttatcgaac gcgccgatgc gttacccgcg tttgaaaaag cctatggctt
    14881 taagctcggt caggatcagt tgctgtcact ggctggtggc gacacggcgg tgacgatcaa
    14941 agccgctgcc cagcaaacct ctggcgttaa tgctgcaatg gcttacggca ctgacggccc
    15001 ggtagcggcg ctggggctgc aaaccttaag cgatccgcaa ggtgtgcaac ctatctacgc
    15061 gcctgcacca gtggtgcgtg agtcggtgtt gaaggagtat ccgcaaatgg cacagtggct
    15121 acagccagtc ttcgccagcc tcgatgcaaa aacattgcag caactgaatg ccagcattgc
    15181 tgtggaagga ctggatgcca aaaaagtggc tgccgactac ctgaaacaaa aagggtggac
    15241 gaagtaattt cccgtgactt atttccgtat taatcctgtt ctggcgctgc tgctgttgct
    15301 gacggcaatc gcagcggcgc tgccgtttat cagttacgcg cctaatcgtt tagtttcggg
    15361 tgaggggcgt catctctggc agctgtggcc gcaaacgatc tggatgctgg tgggcgttgg
    15421 ttgcgcctgg ctgacggcct gttttattcc cggtaaaaaa ggcagcattt gtgcactcat
    15481 tctggcgcaa ttcgtcttcg tattgctggt gtggggcgcg ggaaaggcgg cgacacaact
    15541 ggcgcaaaat ggcagtgcgc tggcgcgtac cagcctcggc agtggtttct ggctggctgc
    15601 ggcgctggca ttgctggcct gtagcgatgc catccgccga atctccacgc atccgctgtg
    15661 gcgctggttg ttgcatatgc agattgccat tattccgctg tggttgctgt actccggcac
    15721 gcttaacgat ctctcactaa tgaaagaata cgccaaccgt caggatgtgt ttgacgacgc
    15781 gctggcacaa catctgacgt tgctgtttgg tgcggtgctg cctgcgttag tgattggtgt
    15841 gccgttgggc atctggtgct acttttccac tgctcggcag ggggcaattt tttctctgct
    15901 caatgtcatt cagaccgtgc cttcggtggc gctctttggc ctgttgattg cgccgcttgc
    15961 cgcgctggtt acggcctttc cgtggctggg gaagctcggc atagcaggaa ccggaatgac
    16021 acccgcactg attgcgctgg tgctctatgc cttgctgccg ctggtgcgcg gcgtggtagt
    16081 cggtttgaac cagatcccgc gcgatgtgct ggagagcgcc agagcgatgg gcatgagcgg
    16141 ggcgcagcga ttcctgcatg ttcagttacc actggcgtta ccggtatttc tgcgcagcct
    16201 gcgggtggtg atggtgcaaa ctgtaggtat ggcggtgatt gcggcgttaa tcggcgcagg
    16261 cggttttggt gcgctggttt tccaggggct gctaagcagc gccattgatt tagtgttgct
    16321 gggggtgatc ccggtaattg ttctggcggt gcttaccgac gcgctgttcg atttgcttat
    16381 cgcactgctg aaggtgaaac gtaatgattg aatttagcca tgtcagcaaa ctgttcggcg
    16441 cacaaaaagc cgttaacgat ctcaatctca attttcagga agggagtttt tcggtgctga
    16501 ttggcacatc tggctccggc aaatccacca ccctgaaaat gattaaccgc ctggtggagc
    16561 atgacagcgg agtgatccgc tttgccggag aagaaattcg ctcgctgcca gtactggagt
    16621 tgcgccgccg gatgggctat gccattcaat ctattggcct gttcccccac tggagcgtgg
    16681 cgcaaaacat cgctaccgtg ccgcaattac aaaaatggtc gcgggcgcgg attgatgatc
    16741 gtatcgacga attaatggcg ctactggggc tggagtcaaa tttacgtgag cgttatccgc
    16801 atcagctttc cggtggtcag cagcaacgtg tgggagtggc gcgcgcactg gctgccgatc
    16861 cgcaagtctt actgatggat gaaccttttg gcgcactgga cccggtaacg cgcggcgcgt
    16921 tgcaacaaga gatgacgcgc attcaccgtt tgctggggcg taccattgtg ctggtcactc
    16981 atgatattga tgaggcgcta cggctggcag aacatctggt attgatggat cacggtgaag
    17041 tggtgcagca ggggaatccg ctgacgatgc tgactcgtcc ggcgaatgat tttgtccgcc
    17101 agttttttgg acgtagtgaa ctgggggtgc gcctgctttc gttacgtagt gtggcggatt
    17161 acgtgcgtcg cgaagaacgg gcagaaggtg aggcactggc agaagagatg acgctacgcg
    17221 atgcgctctc cctgtttgtc gcgcggggat gcgaggtgct gccggtggtg aacacgcagg
    17281 gccagccttg cggcacgctg cattttcagg atctgctgga ggaggcgtaa gcgtatgaag
    17341 atgttgcgcg atccgctgtt ctggctcatt gctttgtttg tggcactgat tttctggctg
    17401 ccttacagcc agccgctgtt tgctgccttg ttcccacaac tgccacgacc cgtttatcag
    17461 caagaaagtt ttgcagctct ggcactggct catttctggc tggtgggaat ttcgagtttg
    17521 tttgcggtga tcattggcac tggtgccgga attgctgtca ctcgcccgtg gggcgcggaa
    17581 tttcgcccac tggtggaaac tattgccgcc gttggacaga cttttccgcc tgtcgcagtg
    17641 ctggcgattg ccgttccggt gatcggcttt ggtctgcaac cagcgattat cgccttgatc
    17701 ctttacggtg tgctgcccgt cctgcaggcg acacttgccg ggctgggagc gattgatgcc
    17761 agcgtgacag aagttgcgaa aggtatggga atgagtcgag gtcagcgact gcgtaaggtc
    17821 gagctaccgc tggcggctcc ggtgattctg gcgggcgtgc gaacttcggt gattatcaac
    17881 attggtacgg cgacgatcgc ctcaacggta ggggccagca cgctgggtac gcccatcatc
    17941 atcgggctta gcggatttaa taccgcgtat gtgatccagg gggcgttact ggtggcactg
    18001 gcggcgatca tcgcagaccg actgtttgaa aggctggtgc aggcgcttag ccagcacgca
    18061 aaataaaggt ataacctgcg agcatgacgc caccaattcc gcctaacgcc ataaacagga
    18121 acagggcgat gaccccaatt ttagctatgc gcatattgca ctccttatgt taacgaaagg
    18181 attgtacagt aaagcgcatt tgttaacgaa tcattaaatg ccgagtggga aaatatcatg
    18241 gccttgttct tgccaactgg tgagttgctg ctgttgggcg gaggttcgat tttcaccgca
    18301 ccacaccagc aatgtacggc cttcgaatag ttcagggcgt agttgattga gcgagtgggc
    18361 gaggacatca atgcgccatc cttgttgact ggcaatccag ccctccagcc acagacgggt
    18421 ggtatcctga atattccagc caaccaccag cgcatcttta ccctgttttt tacgtgccga
    18481 agccagacaa atggcgatgt agttgatcag tacgccgtcg aggatcgcca gcagcgcctg
    18541 gagagtcggt tgttggcact gaagccgtcg gcgcagagga ataaacagat gtgtggtgag
    18601 tgtctgggcg gggtaatcct gaccgcgctc tttgatccac gttcgcaggc tatgcagatt
    18661 gccgctttgc aggtaggtca gtaatgtttc ttgctgatcg cgccagccgt tctgcacatc
    18721 aacattttca ttactgagca gcattttaac tttgctgacc tgcacgccgt tgtcgatcca
    18781 gcgtttgatc tcgcggatac ggtcaatatc ggcatcgttg aacagccgat gaccgccgtc
    18841 tgtccgttgc ggtttcagca acccgtaacg cctctgccac gcgcgtaacg tgacagggtt
    18901 aatatcacaa agcaacgcca cttcaccaat tgtgtaaagc gccatcgtct cacccttgct
    18961 cgcgaggtcc cggtttaact ttagacgcag ttttgcgaac caggtagttt tgcccgtttt
    19021 ttgtgcatct atagggtgat tttatttttg ccaggcgatt ttgagtgatc gtactcacga
    19081 attctcattt ttctgcaaga gttcaaagaa agttaaacgc aggcaatgta tgttacgcgt
    19141 tttaaaggga agtgtggttt gcgggtatgt acgattttaa tctggtgttg ctgctgcttc
    19201 agcagatgtg cgttttttta gtcattgcgt ggttaatgag taaaacgcca ttattcatac
    19261 cgttaatgca ggtcacggtt cgtctgccgc ataaatttct ctgctacatc gtcttttcca
    19321 tcttctgcat catgggcacc tggtttgggt tgcacattga cgattctatt gccaataccc
    19381 gtgcgatagg cgcggtaatg ggcggcttac tcggcggtcc ggtcgtcggt gggctggttg
    19441 gtctgaccgg cggcttacat cgatattcga tggggggcat gaccgcgcta agttgcatga
    19501 tctcaaccat cgttgaagga ttgctcggcg gcctggtaca cagcatcctg atccgtcgcg
    19561 ggcgcactga taaagtcttt aaccccatta ccgccggtgc cgtcacgttc gtcgctgaaa
    19621 tggtgcaaat gctgatcatc cttgcgatcg cccgacctta tgaagatgcg gtgcgtctgg
    19681 tgagtaatat tgctgcacca atgatggtca ccaataccgt cggcgcggcg ctgtttatgc
    19741 gtatattgct cgataaacgc gcgatgtttg aaaaatacac ttctgctttt tctgccactg
    19801 cgctgaaagt ggcagcctcg acggaaggca ttttgcgaca ggggtttaac gaagtgaaca
    19861 gcatgaaagt ggctcaggtg ctgtatcagg agctggatat tggtgcagtc gcgattaccg
    19921 atcgagagaa attgctggcc tttaccggaa ttggtgacga ccaccattta cccggcaaac
    19981 cgatttcttc gacttacacc ttaaaagcga ttgaaaccgg tgaagtggtc tacgctgatg
    20041 gcaacgaagt accttatcgt tgctctttgc atccgcaatg caaactgggg tcgacgctgg
    20101 taattccgtt gcgtggcgaa aatcagcgcg tgatgggcac catcaaattg tatgaagcca
    20161 aaaaccgttt attcagttca atcaaccgca cgctgggcga ggggattgcg caactgcttt
    20221 cggcgcagat cctcgccggg caatatgagc ggcaaaaagc gatgctcacc cagtcagaga
    20281 tcaaactgct tcacgcccag gtgaaccccc attttttgtt taatgcgctt aacaccatta
    20341 aagcggtgat ccgtcgcgac agcgaacagg ccagccagct ggtgcagtat ctttccactt
    20401 ttttccgcaa aaacttaaag cggccttcgg agtttgttac tctcgccgac gaaattgaac
    20461 atgtgaacgc ttatctgcaa attgaaaagg cgcgcttcca gtcgcggttg caggtcaaca
    20521 ttgctattcc gcaagaatta tcccagcagc aattgcccgc gtttaccctg caaccgatag
    20581 tggaaaacgc cattaaacat gggacatcac aactgctgga tacagggcga gtggcaatca
    20641 gcgcccgacg tgaggggcaa catttgatgc tggagatcga agacaatgcc ggtttgtatc
    20701 aaccggtaac caatgccagt gggctgggga tgaatctggt ggataagcgt ttacgtgaac
    20761 ggtttggcga tgactatggg ataagcgtcg cctgtgagcc tgatagttac acccgaataa
    20821 cgttacgact accatggagg gacgaggcat gattaaagtc ttaattgtcg atgatgaacc
    20881 gttagcacgg gagaacctgc gcgtattttt gcaggagcag agcgatattg aaatcgttgg
    20941 agagtgttca aacgccgtgg aagggatcgg cgcggtgcat aaactgcgcc cggatgtgct
    21001 gtttctcgat atccagatgc cgcgcatcag tggtctggaa atggtgggga tgctcgatcc
    21061 ggaacatcgt ccgtatattg tttttctcac cgcgtttgac gaatacgcta ttaaagcctt
    21121 tgaagaacat gcttttgatt atctgctgaa gccaattgat gaagcgcgac tggagaaaac
    21181 gctggcgcga ttgcgtcagg agcgcagcaa gcaggatgtt tcgctgttac cggaaaatca
    21241 acaggcgctg aaatttatcc cttgtacggg gcatagtcgg atttatttgc tgcaaatgaa
    21301 agatgtggca tttgtcagca gtcggatgag cggtgtctac gttaccagcc acgaagggaa
    21361 agagggcttt accgaattga cattacgtac cctggaaagt cgtacaccac tactgcgctg
    21421 ccatcgtcag tatctggtta atctcgcgca tttacaggag attcgtctgg aagataatgg
    21481 ccaggccgag ttgattttgc gtaatggctt aaccgtgccg gtcagccgcc gttatctgaa
    21541 aagcttaaaa gaggcgattg gcctgtaaaa gactgctaaa atggcttttt gcctcatcaa
    21601 cacctgaagg cctcatgcta agtaacgata ttctgcgcag cgtgcgctac attttgaaag
    21661 ccaataataa tgacctggtg cgtattctgg cgctgggtaa tgtcgaagcc accgcggaac
    21721 agatcgccgt ctggctacgt aaagaagacg aagagggttt tcagcgttgt ccggacattg
    21781 ttttgtcgtc attcctcaac ggcctgattt atgaaaaacg cggcaaggat gagtctgctc
    21841 cgccactgga gccggaacgt cgcattaata acaacatcgt gctgaaaaaa ttacgcatcg
    21901 cgttttcgct gaaaaccgat gacattctgg cgatcctcac cgaacagcag ttccgcgttt
    21961 cgatgccgga aattacagcg atgatgcgtg caccggatca taaaaacttc cgcgaatgcg
    22021 gcgatcaatt tttacgttat tttctgcgtg gactggcagc gcgccagcat gtgaaaaaag
    22081 gctaaaaaat tggcggtcat gtttagagca tgaccgccaa ccgattattt cacttcttta
    22141 aaaccagcgg ctttcatcac cagttccatt tgcgccatag tgataccttt tttggcatct
    22201 tcagcagaaa cgttgattcc tgaaataccc tgcagggctt taaaatccac tttttccata
    22261 tcgatagtca cgttttcctg cgcgtaggta tctgtatagg ttaatttttc ttcaacaccc
    22321 gcgatgtttt tgtatttggc gcttaacggc tcaagtgtct tggcagcgtc ttctttggtg
    22381 gttgcaccaa tagaagcaaa ttgaattttg gtttcagaag attgcttaag caccttgtca
    22441 cctttgtaga cataggtaat ggcaatttca gtgccgttca gattggcgct gaatttcttc
    22501 gattcttctt tgtcaccgca gccagcaaga gagaaaacca gaacagatgc aacaacgagg
    22561 gaaaacagct tattgaaagc cttcatgtaa aactccattt tatttaatca agaaactggt
    22621 gactctcacc aggggctata tagaatatgc ctaataccgt gacgtgagca gtccggaact
    22681 ggagtagaac tcttagtaaa aagcactatt tcatccttgt tgctgaagca tggggaataa
    22741 ttgttcgcaa agtaaaacac cgttattcat tgcttctacc cgtgcctcgc tttctgtatt
    22801 acgaaattgt cccaacacat gtgccagccg ataaaaaccg accgcggaga ggtcattcgc
    22861 cagcaactct gcctgactaa tagcgctctg ttcctgatag cgccagccgt tatggagcag
    22921 ttgaataagt aacgcctggc agcgcatcag caactgatga gcggtagacg gcacaggcaa
    22981 aacgctggca gaaggtagcg gtgccacagg cgcagtttcc gcgtccagcg cccaggcgcg
    23041 ggtttttgtc atcatcaccc gtggttccag tgtcaattgc ccatcaacaa aactgacaaa
    23101 gccagaaacc agactcacgg ggtcgtctgt ttgttgcaaa agcgccgcca tgcgttcaac
    23161 ggcaaaagga gaacaggcag atgccggaag ggataacgtc aggagattat cttcaccttc
    23221 gccgctgatt acctgcgcat ccagcgtctg gcggctgcta tcccaaccga gcgaaataca
    23281 ctcagcgacc ggcagaataa ataagttatc gacctgatta agaggccgta tgcaggcggg
    23341 gggacgctgg cgtaaatatt cccgcaaagc cacaatgccc ggctggcgta acggcgcgct
    23401 caacatttgc caggcatcag gcgacagcgg cacaacgctg cttaagcggt tgcgggtagc
    23461 taacagcagc tcgccatcgg cactgcgttt tgctgcttgt gaaacaattt gcccacccgc
    23521 cagtgcgcca gcctgaaaac taaacagccg acgcgtagct gccggtgagt tttcctgttc
    23581 acttcgcggc caactgcgcg aaaggtgcaa aatactgccg gtgtcgggat cggtaaacca
    23641 gatgcgtaaa ccataatgct caatatcctg ccagcaacgc atacctaaag acaccagccg
    23701 cagatgatca agctttgctt ctccggcaat gccagagcca acgaccgtgc gccacggcac
    23761 aggaggaact tcaccaacac tgtcgcgccg ggccatctct tgtgcgcaat ttaatcgact
    23821 gtttaatgcc gcaagctgac gtaagcattc tccggcatga tagtggctgg cgcgagtgtg
    23881 gaaggcatca acgcttgccc gtagctgtcg tagtgattca ctcacccagc gccagttgca
    23941 ggcctctgcc gcctgcaatg cgcggttgaa tgctgcctcg tagtgaataa gcggctggct
    24001 gatgccgcca agccataatg cctggcttaa ttgctgaaca tattgacgac acgtttggcc
    24061 ttcttcgctg gcaaacggat cgtcagatga tgtgacgtgt tcgctgcgca tctgccagat
    24121 taaatggtta aattctgctt gctgcgcttt ggcctcgacg aaggcctgca cagccagtac
    24181 gacatgttcg caaagtgtgc cttcaataca atcacaacgg gcgaaacgaa tactgctacg
    24241 ggaataaaaa cgcacatcgc tcatcggtaa gcgggcagag ggaatttcgc ccggcgcaca
    24301 gaacaactca atggtgatgc ctttagcgac cagcgcctgc gcgcgtttgc gggtggcatc
    24361 gggcagggta gccagttctt ccagccagat tgccggatcc cactcttctt ctttttccgt
    24421 gggctggacg gtggcacaaa gccgttgata acttaacacc agcatcacgc gatgacggca
    24481 catgccgctg gccccgcagc tgcactgagc ctctttcagt gcctggctgt tcgccagctg
    24541 ggtacggaca ccgtcactga aggtggcgat taaagcgccg ttctcatggc tgatttccgg
    24601 gacgttgcca ttttccagtt ccttaagact gcgcttaaca aaaccggcat tgcttaacgc
    24661 cgtcagtgcc tgcggtgtca gttctaataa ttccggacgt agtgaattca tgactgaaga
    24721 ttctccgcaa gccatgatgc cagctcgccc ggcgtcatgg cggctatttg tgcgccgaca
    24781 ttaaccagcg cctgggccgt atcgcggtca tagcaaggcg ttgcggtgct atcgagcgct
    24841 gccagtccca gcactttgat gccgctctgg acacactttt tcacctgatg cgtcagcaat
    24901 gatgatgaac ccccttcgta aaaatcgctc acgaggataa tgacgctttt tgctggttgt
    24961 tcaataagtt gccgaccata ctccacggca ctggcgatat tggtcccgcc gcccaactgt
    25021 actttcatta ataactctac cggatcggca acgtctgccg tgagatcaac cacgcttgtg
    25081 tcaaacgcca ccagatgggt acgaatgccg ggtaactgcc acaaacaggc cgccatcacc
    25141 gcagagtgga tcaccgagtc caccatcgat ccgctttgat caactagtaa gaccagttgc
    25201 cattgttcgc tttggcgttt aatgcggctg ttaaagcggg gggattcgat atacaacttg
    25261 ccgtgttgcg ggtgccagtg ttgcaggttg gcgcgcagag tacttttgaa atcaaagttt
    25321 cgcgccagtg gaattaatga gcggcgacgg cgatcgcgga caccagaaaa agcctgacga
    25381 acttcctttg ccagtcgcgc cataatttct tcaacaacct ggcgcactat ctggcgggcg
    25441 gcagccagta cttcgggatt catcagatgt ttggtgtgca aaacggcgcg tagcaggctt
    25501 tccgaaggct gcatacgttc cagcacgtcg agatttgtca ccacatcttc aatgccgtag
    25561 cgcagtacgg catcgctttc cagccgctca atcacctgtt gcggaaacag cgtgtggata
    25621 ctgttgatcc actcaggagt ggtgagattt gagccaccta atccaccaga gcgttcacca
    25681 cgctggagcc gttcaggatc gcgcccatac agccactcca gcgcgtgatc tatctgccgg
    25741 gcgttgtcat ccagcccaca aagcgtcgtt tctgccgctt cgccaagaat taatcgccag
    25801 cgttgtagct cacgggtggt cagaagatcg ttcagttcag acatggaaaa ctccccagtg
    25861 ttgcagcgat gccagtgcct gctgttcgag ttgttgatga tgtgcaatgg cttgcggtgg
    25921 acaatgcaac ggcatttgca gtgccgaaac gggaagttgc gccagttgat aatgctcaag
    25981 cacctgatgc gccagcgttc cgcgttctcg tggcggtagc caggccatcg ccgcgcgtaa
    26041 atcgggcagg gcattgataa aattggcatc actcagttga ttcaaatggc tgctgaaacc
    26101 ggcgatgaat gcaggttgac aggccagttg atgacgggct aatgccagca aaccgtgcag
    26161 cgcctcgccg gattgtgccg gggataactg cgccagcatc gtcagcgccg cttcggcact
    26221 ggcgttggga tgttccagac gcattagtgc gccaagagcc gcgccgcgat ccagcgccgg
    26281 ggcatgaatc gcctggctgc gtcgctccag taaggctacc gccgcagaaa gcgaaacgcc
    26341 ggataaatta acgccgctat gtagatcgcg cagaatatgg caaagcgctt gccagctatg
    26401 caggtgagcg tgaaactcct tttcatccgg tctgccgtta gattcacaca gccacagcgt
    26461 gcgatcgata gccgcgcata acgtcgtttg taatatctgc gcgccttgca taccgctaat
    26521 ttcatccagc cgccataagg catatagcac ttccagcgcc tggcccattt cggcaaattg
    26581 attttcctgg gcgattaata atgtgagttg ctccagtaat tgttgactga aggacgccag
    26641 acccgctaac gccgcctggc taagacatgt ggtgatactg ccgattccac ccgcgtccag
    26701 catatcggct tctaatttat ggcgtgcggc ttcctgaagt gttgcaccaa agcatgcggc
    26761 ctcaatcaat gccgcatgct ggctaagcgg gcgggttaat ttccagtgtt cttcaccgtt
    26821 gcctgcaagt gtcagtgtac ttccctgctg gcgtacaatc ccagggatct ccagtattgc
    26881 cagccgatgt aacacctgac tttgcgccag cccatcgggg gtaaagcgat ttaaggtaag
    26941 ctccgccgga agagagattg cggtacgttc cagttcgcag gtgacatctt ttggcagagg
    27001 cggttgtggc gtggaagggg caagtttacc gaatccgtca cccgctaatg tgtctatcaa
    27061 cgttagcaga atcggatcgg tatcgggatg aataacgccg cgatagctcc acggcaacgg
    27121 tgcattcagg gcttctttaa tcaacgagcc tgctatggca tccagccagt cagtgcgtaa
    27181 cggtagtgta tgaccgcgca actgtgccag tgccattgca tgcagatgtg cggcagccat
    27241 atccgcggtc gaagcaggca agttgtgctg gcgcaaacgg gtgagaaccg tttttagcag
    27301 ttgttcaccg gcctgctgta agccccactg ccagcaccag ttttgccaga ccggggcagg
    27361 cataccggaa aggtatcctg ccagcacatc aaggcgcttt tcactgtagg gcgtgagata
    27421 acaacctgta atggcatctg ccagcgaggg caattccggc gtgttaatgt cctgcgggca
    27481 ttcgcgccac atttttgcca gtgccggagc gtgccagcca ccgcagacga ctaacacgtc
    27541 gccattattt tgctgcaccg cccatgcaat ccagcgagcc ataaaggctt cgcgctgacg
    27601 attgagtgca tcgccgggga aatcgccccg cagttgggca aaatagtgcg ccagcgcaga
    27661 gggtaatgca gtttgctggc tttcatcttc gaacaagtga tcccacaggg tatcgctgtt
    27721 atccatgcgg gtggcacgca gcagtaaggc ctggctttca tcttgcgtat caggcgaatc
    27781 gtcctcttct tcactctgcg cccagcaagg caaatcgatg aagtaagttt gtgcctgaat
    27841 acgacgtgcg gcttgtagcg cctgccactc cggcgaaaat tcagcaaatg gcgtccaggc
    27901 accacgcccg ggggctgcac cgtcctgata ctggcaataa ctgtaaatag ctaccggaag
    27961 ctggtgggga aaaaaaaagt tcgtctaccc ggtcattaaa atcagccggg ccttcaatca
    28021 acacgtatcg tggccgctgg ctttcgatta acgatttcac cagccgggcg caggccggac
    28081 tatgatgccg gatgccgaca attaacggct cgctcatgca tctttcctca cggcaggcgg
    28141 tggcgggctt gataataagc ctgccagtga gcttctttat gtgtggcgac tcgttgttcg
    28201 aagtaacggc gcagacgagc gcgatcttct tcgttatctt tgacgatggt tccggcaatg
    28261 cagtccacca ggtcggctgg ctcacctgcg cgattcgcta aaaaccaggc gcggacgcct
    28321 acggcgtggg ccacgttcac ggcttcagcg gtggacataa tcgctgttag tgtatccatt
    28381 gacgttttct tttcgccgtt ggcacgcaga tcgcggaagg tgcgtaccag taactccagt
    28441 actgcgtcag gcactttatg cggaataccg ctatgggcca gcaaacgcgc cgaagcactg
    28501 gcgaccagtt ccagctcctg ggcgaaatcc ataatcggaa agacggtttc aaaatcgaag
    28561 cgacgcttta gcgcggcact catctcattg acgccgcgat cgcgggtatt ggcagtggca
    28621 ataatattaa agccttcccg cgcatagagc tgactggctt caccggtgag ttctggcacc
    28681 gtcatcaccc tgtcagaaag catacctaac agacagtctt gtacttccag cggtgtacgc
    28741 gttatctctt caaaacggac gattttgccg tcgcgcattc cctggtaaag cggggcaggg
    28801 accagtgctt ccgttgacgg accatggttg ataagcaggg cgtagttcca gccgtacttg
    28861 atttgatctt cggtagtaga tgcgccgccc tggatggtta acccggcatc gccgctaata
    28921 gcggttgcca gtaattcaga caggagagat tttgcggtgc taggttcccc caccaacatc
    28981 aaaccgcgcc cggtggcaag agtgactaac atgcgttcga cagcggaggg actaatcacc
    29041 actttacggc taatattttg cgcgctatcg ccaaggataa aagcacgggc cgcaggcaaa
    29101 cttaactgcc aaccgggcgg gcaaggagcg ttatcatttt gttttaattt tgccagttca
    29161 tcggcgtata acacagcagc aggcggacgc tgcagatgat tattctgcgg tgacatatat
    29221 tcatccctga aatgtattaa tgaaataaac gatattttac gcgcaataaa tgtttggcgc
    29281 attagttgtt tgagcaaaaa atatctggaa agcagatcgc agtaaataaa aaaacctgct
    29341 ggtgaggcag gttcttttat ttactatttt caggcctaac accacagcct gtgcaacatc
    29401 gtgttccaac gaacgaatta taaccacggc tggaccccgt tgcaattaag ataatgagat
    29461 ttataatcca gaccgttggg acgttgcgcc ggatcgg
//
LOCUS       DAPGUL010000052        28919 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.052, whole genome shotgun sequence.
ACCESSION   DAPGUL010000052 DAPGUL010000000
VERSION     DAPGUL010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 28919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28919
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.052"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..1224)
                     /gene="xanQ"
                     /locus_tag="RHX21_002467"
     CDS             complement(<1..1224)
                     /gene="xanQ"
                     /locus_tag="RHX21_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417358.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine/proton symporter XanQ"
                     /protein_id="HDV1987633.1"
                     /translation="MSDINNAGSDLIFELEDRPPFHQALVGAITHLLAIFVPMVTPAL
                     IVGAALQLSAETTAYLVSMAMIASGIGTWLQVNRYGIVGSGLLSIQSVNFSFVTVMIA
                     LGSSMKSDGFHEELIMSSLLGVSFVGAFLVVGSSFILPYLRRVITPTVSGIVVLMIGL
                     SLIKVGIIDFGGGFAAKSSGTFGNYEHLGVGLLVLIVVIGFNCCRSPLLRMGGIAIGL
                     CVGYIASLCLGMVDFSSMRNLPLITIPHPFKYGFSFSFHQFLVVGTIYLLSVLEAVGD
                     ITATAMVSRRPIQGEEYQSRLKGGVLADGLVSVIASAVGSLPLTTFAQNNGVIQMTGV
                     ASRYVGRTIAVMLVILGLFPMIGGFFTTIPSAVLGGAMTLMFSMIAIAGIRIIITNGL
                     KRRETLIVATSLGLGL"
     gene            complement(1389..4259)
                     /locus_tag="RHX21_002468"
     CDS             complement(1389..4259)
                     /locus_tag="RHX21_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase
                     Mo/Fe-S-binding subunit"
                     /protein_id="HDV1987634.1"
                     /translation="MIIHFTLNGAPQELTVNPGENVQKLLFNMGMHSVRNSDDGFGFA
                     GSDAIIFNGNIVNASLLIAAQLEKADIRTAESLGKWNELSLVQQAMVDVGVVQSGYND
                     PAAALIITDLLDRIAAPTREEIDDALSGLFSRDAGWQQYYQVIELAVARKNNPQATID
                     IAPTFRDDLEVIGKHYPKTDAAKMVQAKPCYVEDRVTADACVIKMLRSPHAHALITHL
                     DVSKAEALPGVVHVITHLNCPDIYYTPGGQSAPEPSPLDRRMFGKKMRHVGDRVAAVV
                     AESEEIALEALKLIDVEYEVLKPVMSIDEAMAEDAPVVHDEPVVYVAGAPDTLEDDNS
                     HAAQRGEHMIINFPIGSRPRKNIAASIHGHIGDMDKGFADADVIIERTYNSTQAQQCP
                     TETHICFTRMDGDRLVIHASTQVPWHLRRQVARLVGMKQHKVHVIKERVGGGFGSKQD
                     ILLEEVCAWATCVTGRPVLFRYTREEEFIANTSRHVAKVTVKLGAKKDGRLTAVKMDF
                     RANTGPYGNHSLTVPCNGPALSLPLYPCDNVDFQVTTYYSNICPNGAYQGYGAPKGNF
                     AITMALAELAEQLQIDQLEIIERNRVHEGQELKILGAIGEGKAPTSVPSAASCALEEI
                     LRQGREMIQWSSPKPQNSDWHIGRGVAIIMQKSGIPDIDQANCMIKLESDGTFIVHSG
                     GADIGTGLDTVVTKLAAEVLHCPPQDVHVISGDTDHALFDKGAYASSGTCFSGNAARL
                     AAENLREKILFHGAQMLGEAVADVQLATPGVVRGKKGEVSFGDIAHKGETGTGFGSLV
                     GTGSYITPDFAFPYGANFAEVAVNTRTGEIRLDKFYALLDCGTPVNPELALGQIYGAT
                     LRAIGHSMSEEIIYDAEGHPLTRDLRSYGAPKIGDIPRDFRAVLVPSDDKVGPFGAKS
                     ISEIGVNGAAPAIATAIHDACGIWLREWHFTPEKILTALEKI"
     gene            complement(4256..5035)
                     /locus_tag="RHX21_002469"
     CDS             complement(4256..5035)
                     /locus_tag="RHX21_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase
                     FAD-binding subunit"
                     /protein_id="HDV1987635.1"
                     /translation="MIEQFFRPDSVEQALELKRRYQDEAVWFAGGSKLNATPTRTDKK
                     IAISLQDLELDWVDWDNGALRIGAMSRLQPLRDARFIPAALREALGFVYSRHVRNQST
                     IGGEIAARQEESVLLPVLLALDAELVFGNGETLSIEDYLACPCDRLLTEIIIKDPYRT
                     CATRKISRSQAGLTVVTAAVAMTDHDGMRIALDGVASKALRLHDVEKQNLEGNALEQA
                     VANAIFPQEDLRGSVAYKRYITGVLVADLYADCQQAGEEAV"
     gene            complement(5086..6414)
                     /gene="ssnA"
                     /locus_tag="RHX21_002470"
     CDS             complement(5086..6414)
                     /gene="ssnA"
                     /locus_tag="RHX21_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HDV1987636.1"
                     /translation="MLILKNVTAVQLHPAKVQEGVDIAIENDVIVAIGDALTQRYPDA
                     SYKEMHGRIVMPGIVCSHNHFYSGLSRGIMANIAPCPDFISTLKNLWWRLDRALDEES
                     LYYSGLICSLEAIKSGCTSVIDHHASPAYIGGSLSTLRDAFLKVGLRAMTCFETTDRN
                     NGIKELQEGVEENIRFARQIDEAKKAATEPYLVEAHIGAHAPFTVPDAGLEMLREAVK
                     ATGRGLHIHAAEDLYDVSYSHHWYGKDLLARLAQFDLIDSKTLVAHGLYLSKDDITLL
                     NQRDAFLVHNARSNMNNHVGYNHHLSDIRNLALGTDGIGSDMFEEMKFAFFKHRDAGG
                     PLWPDSFAKALTNGNELMSRNFGAKFGLLEAGYKADLTICDYNSPTPLLADNIAGHIA
                     FGMGSGSVHSVMVNGVMVYEDRQFNFDCDSIYAQARKAAASMWRRMDALA"
     gene            complement(6417..9515)
                     /gene="ygfK"
                     /locus_tag="RHX21_002471"
     CDS             complement(6417..9515)
                     /gene="ygfK"
                     /locus_tag="RHX21_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenate reductase subunit YgfK"
                     /protein_id="HDV1987637.1"
                     /translation="MGDIMRPIPFEELLTRIFDEYQQQRSIFGIPEQQFYSPVKGKTV
                     SVFGETCATPVGPAAGPHTQLAQNIVTSWLTGGRFIELKTVQILDRLELEKPCIDAED
                     ECFNTEWSTEFTLLKAWDEYLKAWFALHLLEAMFQPSDSGKSFIFNMSVGYNLEGIKQ
                     PPMQQFIDNMMDASDHPKFAQYRDTLNKLLQDDAFLARHGLQEKRESLQALPARIPTS
                     MVQGVTLSTMHGCPPHEIEAICRYMLEEKGLNTFVKLNPTLLGYARVREILDVCGFGY
                     IGLKEESFDHDLKLTQALEMLERLMALAKEKSLGFGVKLTNTLGTINNKGALPGEEMY
                     MSGRALFPLSINVAAVLSRAFDGKLPISYSGGASQLTIRDIFDTGIRPITMATDLLKP
                     GGYLRLSACMRELEGSDAWGLDHVDVERLNRLAADALTMEYTQKHWKPEERIEVAEDL
                     PLTDCYVAPCVTACAIKQDIPEYIRLLGEHRYADALELIYQRNALPAITGHICDHQCQ
                     YNCTRLDYDSALNIRELKKVALEKGWDEYKQRWHKPVGSGSRHPVAVIGAGPAGLAAG
                     YFLARAGHPVTLFEREANAGGVVKNIIPQFRIPAELIQHDIDFVAAHGVKFEYGCSPD
                     LTVEQLKNQGFHYVLIATGTDKNSGVKLAGDNQNVWKSLPFLREYNKGTALKLGKHVV
                     VVGAGNTAMDCARAALRVPGVEKATIVYRRSLQEMPAWREEYEEALHDGVEFRFLNNP
                     ECFDADGTLTLRVMSLGEPDEKGRRRPVETNETVTLHVDSLITAIGEQQDTEALNAMG
                     VPLDKNGWPDVDHNGETRLTDVFMIGDVQRGPSSIVAAVGTARRATDAILSRENIRSH
                     QNNKYWNNVNPAEIYQRKGDISITLVNSDDRDAFVAQEAARCLECNYVCSKCVDVCPN
                     RANVSIAVPGFQNRFQTLHLDAYCNECGNCAQFCPWNGKPYKDKITVFSLAQDFDNSS
                     NPGFLVEDCRVRVRLNNQSWVLNIDSEGQFNNVPPELNDMCRIISHVHQHHHYLLGRV
                     EV"
     gene            complement(9837..10415)
                     /gene="mocA"
                     /locus_tag="RHX21_002472"
     CDS             complement(9837..10415)
                     /gene="mocA"
                     /locus_tag="RHX21_002472"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HDV1987638.1"
                     /translation="MSAIDCIITAAGLSSRMGQWKMMLPWQQGTILDTSIKNALQFCS
                     RIILVTGYRGNELHERYANQSNITIIHNPDYAQGLLTSVKAAVPAVQTEHCFLTHGDM
                     PTLTIDIFRKIWSLRNDGAILPLHNGIPGHPILVSKPCLMQAIQRPNVTNMRQALLMG
                     AHYSVEIENAEIILDIDTPDDFITAQKRYTKI"
     gene            10518..11288
                     /gene="yqeC"
                     /locus_tag="RHX21_002473"
     CDS             10518..11288
                     /gene="yqeC"
                     /locus_tag="RHX21_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417352.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HDV1987639.1"
                     /translation="MKSIVDPSALVIDLGAQKRPTVISVVGAGGKTSLLFWLAELLQA
                     SGRRVLITTTTHMFMPTSHWPVVFCRDPAMLPHASLTSPISFCFHSWKANQGKVQGFT
                     PEAIDALVQRPECDVILIEADGSRGMPLKAPDEHEPCIPKSSCCVIAVMGGHTLGAKV
                     STENVHRWSQFADITGLTPDATLQLSDLVALVRHPQGAFKNVPQGCRRVWFINRFSQC
                     ENAIAQSELLQPLQQHDVEAIWLGDIQEHPAIARRFVN"
     gene            11336..12961
                     /locus_tag="RHX21_002474"
     CDS             11336..12961
                     /locus_tag="RHX21_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HDV1987640.1"
                     /translation="MNIFTEAAKLEEQNCPFAMAQIVDSRGSTPRHSAQMLVRADGSI
                     VGTIGGGMVERKVIEESLQALQERKPRLFHGRMARNGADAVGSDCGGAMSVFISVHGM
                     RPRLVLIGAGHVNRAIAQSAALLGFDIAVADIYRESLNPELFPPSTTLLHAESFGAAV
                     EALDIRPDNFVLIATNNQDREALDKLIEQPIAWLGLLASRRKVQLFLRQLREKGVAEE
                     HIARLHAPVGYNIGAETPQEIAISVLAEILQVKNNAPGGLMMKPSHPSGHQLVVIRGA
                     GDIASGVALRLYHAGFKVIMLEVEKPTVIRCTVAFAQAVFDGEMTVEGVTARLATSSA
                     EAMKLTERGFIPVMVDPACSLLDELKPLCVVDAILAKQNLGTRADMAPVTIALGPGFT
                     AGKDCHAVIETNRGHWLGQVIYSGCAQENTGVPGNIMGHTTRRVIRAPAAGIMRSNVK
                     LGDLVKEGDVIAWIGEHEIKAPLTGMVRGLLNDGLAVVGGFKIGDIDPRGETADFTSV
                     SDKARAIGGGVLEALMMLMHQGVKATKEVLEVA"
     gene            complement(13002..13934)
                     /gene="arcC"
                     /locus_tag="RHX21_002475"
     CDS             complement(13002..13934)
                     /gene="arcC"
                     /locus_tag="RHX21_002475"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HDV1987641.1"
                     /translation="MSKKIVLALGGNALGDDLAGQMKAVKITSQAIVDLIAQGHEVIV
                     THGNGPQVGMINQAFEAAAKTEAHSPMLPMSVCVALSQGYIGYDLQNALREELLSRGI
                     NKPVATLVTQVEVDANDPAFLNPTKPIGSFFTEQEAEQLTKQGYTLKEDAGRGYRRVV
                     ASPKPVDIIEKETVKALVDAGQVVITVGGGGIPVIREGNHLRGASAVIDKDWASARLA
                     EMIDADMLIILTAVEKVAINFGKENEQWLDRLSLSDAERFIEEGHFAKGSMLPKVEAA
                     ASFARSRAGREALITVLSKAKEGIEGKTGTVICQ"
     gene            complement(13982..15367)
                     /gene="hyuA"
                     /locus_tag="RHX21_002476"
     CDS             complement(13982..15367)
                     /gene="hyuA"
                     /locus_tag="RHX21_002476"
                     /EC_number="3.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311773.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-phenylhydantoinase"
                     /protein_id="HDV1987642.1"
                     /translation="MRVLIKNGTVVNADGQAKQDLLIESGIVRQLGNNISPQLPYEEI
                     DATGCYVFPGGVDVHTHFNIDVGIARSCDDFFTGTRAAACGGTTTIIDHMGFGPNGCR
                     LRHQLEVYRGYAAHKAVIDYSFHGVIQHINHAILDEIPMMVEEGLSSFKLYLTYQYKL
                     NDDEVLQALRRLHESGALTTVHPENDAAIASKRAEFIAAGLTAPRYHALSRPLECEAE
                     AIARMINLAQIAGNAPLYIVHLSNGLGLDYLRLARANHQPVWVETCPQYLLLDERSYD
                     TEDGMKFILSPPLRNVREQDKLWCGISDGAIDVVATDHCTFSMAQRLQISKGDFSRCP
                     NGLPGVENRMQLLFSSGVMTGRITPERFVELTSAMPARLFGLWPQKGLLAPGSDGDVV
                     IIDPRQSQQIQHRHLHDNADYSPWEGFTCQGAIVRTLSRGETIFCDGTFTGKAGRGRF
                     LRRKPFVPPVL"
     gene            complement(15420..16631)
                     /locus_tag="RHX21_002477"
     CDS             complement(15420..16631)
                     /locus_tag="RHX21_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HDV1987643.1"
                     /translation="MAKNIPFKLILEKAKDYQADMTRFLRDMVAIPSESCDEKRVVHR
                     IKEEMEKVGFDKVEIDPMGNVLGYIGHGPRLVAMDAHIDTVGIGNIKNWDFDPYEGME
                     TDELIGGRGTSDQEGGMASMVYAGKIIKDLGLEDEYTLLVTGTVQEEDCDGLCWQYII
                     EQSGIRPEFVVSTEPTDCQIYRGQRGRMEIRIDVQGVSCHGSAPERGDNAIFKMGPIL
                     GELQELSQRLGYDEFLGKGTLTVSEIFFTSPSRCAVADSCAVSIDRRLTWGETWEGAL
                     DEIRALPAVQKANAVVSMYNYDRPSWTGLVYPTECYFPTWKVEEDHFTVKALVNAYEG
                     LFGKAPVVDKWTFSTNGVSIMGRHGIPVIGFGPGKEPEAHAPNEKTWKSHLVTCAAMY
                     AAIPLSWLATE"
     gene            complement(16689..17885)
                     /gene="dpaL"
                     /locus_tag="RHX21_002478"
     CDS             complement(16689..17885)
                     /gene="dpaL"
                     /locus_tag="RHX21_002478"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HDV1987644.1"
                     /translation="MSVFSLKIDIADNKFFNGETSPLFSQSQAKLARQFHQKIAGYRP
                     TPLCALDDLANLFGVKKILVKDESKRFGLNAFKMLGGAYAIAQLLCEKYHLDIETLSF
                     EHLKNAIGEKMTFATTTDGNHGRGVAWAAQQLGQNAVIYMPKGSAQERVDAILNLGAE
                     CIVTDMNYDDTVRLTMQHAQQHGWEVVQDTAWEGYTKIPTWIMQGYATLADEAVEQMR
                     EMGVTPTHVLLQAGVGAMAGGVLGYLVDVYSPQNLHSIIVEPDKADCIYRSGVKGDIV
                     NVGGDMATIMAGLACGEPNPLGWEILRNCATQFISCQDSVAALGMRVLGNPYGNDPRI
                     ISGESGAVGLGVLAAVHYHPQRQSLMEKLALNKDAVVLVISTEGDTDVKHYREVVWEG
                     KHAVAP"
     gene            complement(17943..19130)
                     /gene="ygeW"
                     /locus_tag="RHX21_002479"
     CDS             complement(17943..19130)
                     /gene="ygeW"
                     /locus_tag="RHX21_002479"
                     /EC_number="2.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311770.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="knotted carbamoyltransferase YgeW"
                     /protein_id="HDV1987645.1"
                     /translation="MKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAAL
                     KALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIAHGE
                     TVRETANMISFCADAIGIRDDMFLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQC
                     DIDHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFG
                     MDVTLAHPEGYDLIPDVVEVAKNNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKV
                     MEQRTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELTRDGEALYMHCLPADI
                     SGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQE
                     RVK"
     gene            19609..21387
                     /locus_tag="RHX21_002480"
     CDS             19609..21387
                     /locus_tag="RHX21_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001465538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HDV1987646.1"
                     /translation="MELATTQSVLMQIQPTIQRFARMLASVLQLEVEIVDENLCRVAG
                     TGAYGKFLGRQLSGNSRLLRHVLETKTEKVVTQSRFDPLCEGCDSKENCREKAFLGTP
                     VILQDRCVGVISLIAVTHEQQEHISDNLREFSDYVRHISTIFVSKLLEDQGPGDNISK
                     IFATMIDNMDQGVLVVDDESRVQFVNQTALKTLGVVQNNIIGKPIRFRPLTFESNFTH
                     GHMQHIVSWDDKSELIIGQLHNIQGRQLFLMAFHQSHTSFSVANAPDEPHIEQLVGEC
                     RVMRQLKRLISRIAPSPSSVMVVGESGTGKEVVARAIHKLSGRRNKPFIAINCAAIPE
                     QLLESELFGYVKGAFTGASANGKTGLIQAANTGTLFLDEIGDMPLMLQAKLLRAIEAR
                     EILPIGASSPIQVDIRIISATNQNLAQFIAEGKFREDLFYRLNVIPITLPPLRERQED
                     IELLVHYFLHQHTRRLGSVYPGIAPDVVEILRKHRWPGNLRELSNLMEYLVNVVPSGE
                     VIDSTLLPPNLLNNGTTEQSDVTEVSEAHLSLDDAGGTALEEMEKQMIREALSRHNSK
                     KQVADELGIGIATLYRKIKKYELLNI"
     gene            complement(21427..21906)
                     /gene="xdhC"
                     /locus_tag="RHX21_002481"
     CDS             complement(21427..21906)
                     /gene="xdhC"
                     /locus_tag="RHX21_002481"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase iron sulfur-binding
                     subunit XdhC"
                     /protein_id="HDV1987647.1"
                     /translation="MNHSETITIECTINGMPFQLHAAPGTPLSELLREQGLLSVKQGC
                     CVGECGACTVLVDGTAIDSCLYLAAWAEGKEIRTLEGEAKGGKLSHVQQAYAKSGAVQ
                     CGFCTPGLIMATTAMLAKPREKPLTITEIRRGLAGNLCRCTGYQMIVNTVLDCEKTK"
     gene            complement(21903..22781)
                     /gene="xdhB"
                     /locus_tag="RHX21_002482"
     CDS             complement(21903..22781)
                     /gene="xdhB"
                     /locus_tag="RHX21_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase FAD-binding subunit XdhB"
                     /protein_id="HDV1987648.1"
                     /translation="MFDFASYHRAATLADAINLLADNPQAKLLAGGTDVLIQLHHHND
                     RYRHIVDIHNLAELRGITLAEDGSLRIGSATTFTQLIEDPITQRHLPALCAAATSIAG
                     PQIRNVATYGGNICNGATSADSATPTLIYDAKLEIHSPRGVRFVPINGFHTGPGKVSL
                     EHDEILVAFHFPPQPKEHAGSAHFKYAMRDAMDISTIGCAAHCRLDNGNFSELRLAFG
                     VAAPTPIRCQHAEQTAQNAPLNLQTLEAISESVLQDVAPRSSWRASKEFRLHLIQTMT
                     KKVISEAVAAAGGKLQ"
     gene            complement(22792..25089)
                     /gene="xdhA"
                     /locus_tag="RHX21_002483"
     CDS             complement(22792..25089)
                     /gene="xdhA"
                     /locus_tag="RHX21_002483"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase molybdenum-binding
                     subunit XdhA"
                     /protein_id="HDV1987649.1"
                     /translation="MEAREATATGESCMRVDAIAKVTGRARYTDDYVMAGMCYAKYVR
                     SPIAHGYAVSINDEQARSLPGVLAIFTWEDVPDIPFATAGHAWTLDENKRDTADRALL
                     TRHVRHHGDAVAIVVARDELTAEKAAQLVSIEWQELPVITTPEAALAEDAAPIHNGGN
                     LLKQSTMSTGNVQQTIDAADYQVQGHYQTPVIQHCHMESVTSLAWMEDDSRITIVSST
                     QIPHIVRRVVGQALDIPWSCVRVIKPFVGGGFGNKQDVLEEPMAAFLTSKLGGIPVKV
                     SLSREECFLATRTRHAFTIDGQMGVNRDGTLKGYSLDVLSNTGAYASHGHSIASAGGN
                     KVAYLYPRCAYAYSSKTCYTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVEI
                     RLRNAAREGDANPLTGKRIYSAGLPECLEKGRKIFEWEKRRAECQNQQGNLRRGVGVA
                     CFSYTSNTWPVGVEIAGARLLMNQDGTINVQSGATEIGQGADTVFSQMVAETVGVPVS
                     DVRVISTQDTDVTPFDPGAFASRQSYVAAPALRSAALLLKEKIIAHAAVMLHQSAMNL
                     TLIKGHIVLVERPEEPLMSLKDLAMDAFYHPERGGQLSAESSIKTTTNPPAFGCTFVD
                     LTVDIALCKVIINRILNVHDSGHILNPLLAEGQVHGGMGMGIGWALFEEMIIDAKSGV
                     VRNPNLLDYKMPTMPDLPQLESAFVEINEPQSAYGHKSLGEPPIIPVAAAIRNAVKMA
                     TGVAINTLPLTPKRLYEEFHLAGLI"
     gene            25504..26259
                     /locus_tag="RHX21_002484"
     CDS             25504..26259
                     /locus_tag="RHX21_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311765.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HDV1987650.1"
                     /translation="MSAGRLNKKSLGIVMLLSVGLLLAGCSGSKSSDTGTYSGSVYTV
                     KRGDTLYRISRTTGTSVKELARLNGISPPYTIEVGQKLKLGGAKSSSSTRKSTAKSTT
                     KTASVTPSSAVPKSSWPPVGQRCWLWPTTGKVIMPYSTADGGNKGIDISAPRGTPIYA
                     AGAGKVVYVGNQLRGYGNLIMIKHSEDYITAYAHNDTMLVNNGQSVKAGQKIATMGST
                     DAASVRLHFQIRYRATAIDPLRYLPPQGSKPKC"
     gene            26338..26411
                     /locus_tag="RHX21_002485"
     tRNA            26338..26411
                     /locus_tag="RHX21_002485"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:26370..26372,aa:Gly,seq:ccc)
     gene            26645..28255
                     /locus_tag="RHX21_002486"
     CDS             26645..28255
                     /locus_tag="RHX21_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001613747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987651.1"
                     /translation="MKGKSALTLLLAGIFSCGTCQATGAEVTSESVFNILNSTGAATD
                     KSYLSLNPDKYPNYRLLIHSAKLQNEIKSHYTKDEIQGLLTLTENTRKLTLTEKPWGT
                     FILASTFEDDKTAAETHYDAVWLRDSLWGYMALVSDQGNSVAAKKVLLTLWDYMSTPD
                     QIKRMQDVISNPKRLDGVPGQMNVVHIRFDSNSPVMADVQEEGKPQLWNHKQNDALGL
                     YLDLLIQAIDTDTINAEDWQKGDRLKSVALLIAYLDKANFYVMEDSGAWEEDARLNTS
                     SVALVTSGLERLSNLLSKKDSVFVSDLLREAKANELDEPLSTTRLNHLIDKGYERITL
                     QLDLGGESPGYLEKDKHYREADAALLNVIYPANLAKINTRRKEQVLKIVKKLAGPYGI
                     KRYEKDNYQSANFWFNDIKTDTDQNSHAKREKSFIPSTEAEWFFDSWYAKSAAIVYKE
                     SRKEEYLNDSVQFMNRSLAQITGENMIGANGRSVPEMALPESYNYIHKSGTLHEAPSP
                     IIPLNWSKASMTLMLKEMSNLINDEGIK"
     gene            28268..28387
                     /locus_tag="RHX21_002487"
                     /pseudo
     CDS             28268..28387
                     /locus_tag="RHX21_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001314987.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion protein"
     gene            28387..28752
                     /locus_tag="RHX21_002488"
     CDS             28387..28752
                     /locus_tag="RHX21_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000467436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987652.1"
                     /translation="MFGLRKVNRNTHTFETTFQNWKENGEDVALLMPEFSAKWLPIAE
                     ESGSWSGWVLLGEIFPLISSELAGMALMPETERLIGEWLSLSSSPLNLKHPELKYNRL
                     HVGKVFDGVLSPAQPLIRI"
BASE COUNT         7206 a         7005 c         7373 g         7335 t
ORIGIN      
        1 aagccctaaa cctaaagaag tggcgacaat aagtgtttca cggcgcttta aaccgttggt
       61 gatgatgatg cgaatccctg cgatggcaat catggaaaac atcaacgtca ttgcgcctcc
      121 cagaactgcc gagggaatgg tcgtgaagaa gccgccaatc atcggaaata agccgaggat
      181 aaccagcatt accgcgatgg ttcgcccgac ataacgtgaa gcgacgccag tcatctgaat
      241 aaccccatta ttttgcgcaa acgtggttaa tggtaatgaa ccgacagcgg aggcgataac
      301 agaaaccaga ccatctgcca gcacgccgcc tttcagtcgg gactgatact cttccccctg
      361 aatggggcgg cgggaaacca ttgccgtggc ggtgatatcg ccgactgctt ccagcacgct
      421 aagcagataa atcgtgccaa ccaccaggaa ctgatggaag ctaaaactaa agccgtattt
      481 gaacggatgc gggatggtga ttaacggcaa attgcgcata ctgctgaaat ccaccatgcc
      541 caggcataac gatgcgatat agccgacaca tagcccaatg gcgatccctc ccatgcgtag
      601 caacggactg cgacagcagt taaagccgat caccacaatt aaaaccaata aaccaacgcc
      661 gagatgttcg taattgccga atgtaccgct gcttttggct gcaaatcctc caccaaaatc
      721 gataatgccg actttaatca ggcttaagcc gatcatcagt accacaatac cgctgacggt
      781 aggcgtaata acccgacgta aatagggcaa gataaatgaa gatccgacaa ccagaaatgc
      841 gccaacgaag gagacgccga gaagcgacga catgattaac tcttcgtgaa aaccgtcgct
      901 tttcatgctg ctgcccagcg caatcatgac cgtaacaaat gaaaaattga ctgactgaat
      961 tgagagtagg ccagaaccga cgatgccgta gcggtttact tgtaaccagg taccaatacc
     1021 agaggcgatc atcgccatag aaacaagata ggcagttgtt tcagcggaaa gctgtaaggc
     1081 cgcccccacg attaacgcgg gggttaccat cggaacgaaa attgccaaca gatgggtaat
     1141 ggcaccaacg agagcctgat gaaagggagg gcgatcctcc agttcaaata taaggtcaga
     1201 acctgcattg tttatatcag acatcccttc actcctttta aagtaaattt gatcatctga
     1261 attagtaaaa taaattccca cgaatttggg gcgcaggacg ccttgagaac ggcttatctc
     1321 attttcgcag tcactattta gtcatcgtcc aaacagagaa acaggccgcc gaagcggcca
     1381 tttattattt atattttttc cagcgcagtg agtattttct ccggtgtgaa atgccattcg
     1441 cgtaaccaga tgccgcatgc atcgtgaatt gcggtagcaa tcgccggagc tgcgccattt
     1501 acaccgattt ccgagatcga tttcgccccg aacgggccga ctttatcgtc gctcggcacc
     1561 agcacagcgc ggaaatcacg cggaatgtca ccaattttcg gtgcgccgta actgcgtaaa
     1621 tcacgcgtta acgggtgacc ttcggcgtca taaatgatct cttcgctcat actgtggccg
     1681 atagctcgca gggtagcacc gtagatttgt cccaatgcta attccgggtt gaccggtgta
     1741 ccgcagtcca gcaaggcgta gaatttatcc aggcggattt cacccgtacg cgtgttgacg
     1801 gcaacttcag cgaagtttgc gccatacggg aaggcgaaat caggcgtgat ataactgcca
     1861 gttcccacca gtgaaccaaa gccggtgccg gtttcgcctt tatgagcaat atccccgaag
     1921 ctgacttcgc ctttcttgcc gcgcacgacg cccggcgttg ccagttgaac atctgccact
     1981 gcctcaccca acatttgcgc gccgtggaac agaattttct cccgcagatt ttccgctgcc
     2041 aaacgcgccg cgttacccga gaagcaagta ccggacgagg catatgcgcc tttatcaaac
     2101 aacgcatgat cggtatcacc ggagataaca tgcacgtcct gcggtgggca gtgcagcact
     2161 tctgctgcca gtttcgtcac tacagtatcc agaccagtac caatatccgc accgccagaa
     2221 tgaacgataa aggtgccgtc cgattccagt ttgatcatgc agttagcctg atcgatatcc
     2281 gggatacccg atttctgcat gataatggcg acgccgcgac cgatgtgcca gtcactattt
     2341 tgcggtttcg gtgaagacca ttggatcatc tcgcgaccct gacgcaggat ctcttccagt
     2401 gcgcagctgg cggcggaagg aacggaggtc ggcgctttac cttcaccgat tgcaccgaga
     2461 attttcagct cttgcccttc gtgtacccgg ttacgttcga taatttccag ttggtcgatc
     2521 tgtaactgtt cagccagttc cgctaatgcc atggtgatag cgaagttacc tttcggtgcg
     2581 ccataaccct gataagcacc atttgggcaa atgttgctgt agtaggtggt gacctggaaa
     2641 tcgacgttat cgcacggata taacggcagc gacagcgccg gtccgttaca cggtacggtg
     2701 agtgagtggt tgccgtaagg gccagtgttg gcgcggaaat ccatcttcac tgccgtcagg
     2761 cgaccatctt ttttcgctcc cagtttgacg gtgactttcg cgacgtgacg agaggtgtta
     2821 gcaataaact cttcttcacg ggtgtagcgg aacagtaccg gacgcccggt cacgcaggtt
     2881 gcccaggcgc acacttcttc cagcaggatg tcctgtttgg aaccaaaacc gccgccaact
     2941 cgctctttaa tgacatgaac tttatgctgt ttcatgccca cgaggcgcgc gacctggcgg
     3001 cgtaagtgcc atggtacctg ggtggaggcg tggataacca gacgatcgcc gtccatacga
     3061 gtaaagcaga tatgtgtttc agtcgggcac tgctgcgctt gcgttgagtt ataggttcgc
     3121 tcaatgatca catcggcatc ggcaaagcct ttgtccatat cgccaatatg accatgaata
     3181 ctggcggcga tatttttgcg agggcgagaa ccgatcggga agttgatgat catatgctcg
     3241 ccgcgctggg ctgcatggct gttatcgtct tccagagtat ctggcgcacc agcaacatac
     3301 accaccggtt catcgtgcac gacaggcgca tcttccgcca ttgcttcgtc gatcgacatt
     3361 accggcttaa gcacttcata ttcaacgtcg atgagcttca gtgcttcgag cgcaatttct
     3421 tcactttctg cgacgaccgc agcaacacga tcgccgacgt gacgcatttt cttgccgaac
     3481 atacggcggt caagcggtga cggttccggt gcgctctgac cacccggggt atagtagata
     3541 tccgggcaat tcaggtgagt aataacgtga acgacgcccg gtaaggcttc agctttgctg
     3601 acatccagat gagtaatcag tgcgtgagcg tgtgggctac gtaacatttt aatgacgcag
     3661 gcgtcagccg ttacgcggtc ttcaacatag cagggtttcg cctgcaccat tttcgcggca
     3721 tcagttttag gataatgctt accaatgact tctaggtcgt cacggaaagt cggagcgata
     3781 tcaatggtgg cctgcggatt atttttacgt gcaaccgcca gttcaatgac ctgatagtat
     3841 tgctgccagc cagcatcgcg gctgaacaaa ccagaaagcg cgtcgtcgat ctcttcgcgg
     3901 gtaggtgcgg cgatgcgatc gagaagatcg gtgataatca gagctgcagc tggatcgtta
     3961 taaccagact gcaccacgcc aacatcaacc attgcctgtt gaaccagact taactcgttc
     4021 catttgccca gagattctgc ggtacgaata tctgccttct ctaactgtgc ggcaataagc
     4081 aaggacgcgt taacgatatt accgttaaag attattgcgt cagaaccggc aaacccgaaa
     4141 ccatcatcac tgttgcgtac agagtgcatt cccatgttaa acaacagctt ttgcacgttt
     4201 tcgcctggat taacggttag ctcctgaggc gcgccattta aagtaaagtg gatgatcata
     4261 cggcttcctc cccagcctgt tggcagtcgg catacaggtc ggctaccaga actcccgtga
     4321 tatagcgttt ataggccacg ctgccccgca aatcttcctg cgggaaaatg gcgttggcga
     4381 cagcctgttc aagtgcattg ccttccagat tttgtttttc gacatcatgc agacgcagtg
     4441 ctttactggc gacgccatcc agcgcaattc gcataccgtc gtggtctgtc attgcaacgg
     4501 ctgccgtcac gacggttaaa cctgcctgag aacggctaat tttgcgggtc gcacaggtgc
     4561 gatacggatc tttaatgata atttcggtta gcaggcgatc gcatgggcag gccaggtagt
     4621 cctcgattga cagcgtttcg ccgttgccaa aaaccagttc agcatccagt gccaacagga
     4681 cgggaagcag caccgactct tcctggcggg cggcgatttc accaccaatg gtcgactgat
     4741 tacgaacatg gcgtgagtaa acaaaaccga gggcttcacg cagcgctgca ggaataaatc
     4801 gcgcatcacg cagtggctgc aagcgagaca ttgcgccaat ccgcagtgca ccgttatccc
     4861 agtcaaccca gtccagttcc agatcctgta aggaaatggc aatcttttta tcggtacggg
     4921 ttggtgtagc attgagtttg ctgcccccgg cgaaccagac ggcttcatcc tggtagcggc
     4981 gcttcagttc cagcgcctgt tcgacagagt cgggcctgaa aaattgttca atcatcttct
     5041 ttccttattt aaccctcttc cctgcgggaa gagggcatct gtcatttatg ccagcgcatc
     5101 catccgacgc cacatactgg cagcggcttt tctggcttgt gcataaatgg aatcgcaatc
     5161 gaagttaaac tgacggtctt catagaccat cacaccattg accattacgc tgtgaacgct
     5221 gcctgagccc ataccgaaag cgatatgccc ggcgatattg tctgccagca gcggcgtcgg
     5281 cgagttgtaa tcgcaaatgg ttaaatcagc tttgtaaccg gcttccagaa gcccaaattt
     5341 cgcgccaaag ttgcggctca tcagttcgtt accgttagtc agggctttgg caaaactgtc
     5401 aggccacagc ggaccacccg catcgcgatg tttaaagaag gcaaatttca tctcttcaaa
     5461 catgtccgaa ccaatgccgt ccgttcccaa cgccagattg cggatgtcgc taaggtgatg
     5521 gttgtagccg acatggttgt tcatgtttga acgggcgtta tgcaccagga acgcatcgcg
     5581 ctgattgagt agggtgatgt catctttcga caagtacagc ccatgagcga ccagcgtttt
     5641 gctgtcgatg agatcgaatt gcgccagtcg tgccagcagg tctttgccgt accagtggtg
     5701 actgtaggaa acgtcgtaaa ggtcttccgc agcgtgaata tgcaaaccac ggcctgtggc
     5761 tttcacggct tcacgcagca tctccagacc ggcatccggc acggtaaacg gcgcgtgagc
     5821 accgatatgt gcttccacca gatacggctc ggttgctgct ttcttcgcct catcaatctg
     5881 acgggcaaag cggatgtttt cttctacacc ttcctgcaac tctttgatgc cgttgttacg
     5941 gtcagtagtt tcaaaacagg tcattgcgcg caggccaact tttaaaaatg cgtcgcgcaa
     6001 tgtggagagc gacccgccga tatacgccgg agaggcatgg tgatcgataa ccgatgtaca
     6061 tccgctctta atcgcttcca gggaacaaat cagtccgctg taatagagcg actcttcatc
     6121 aagggcgcga tcgagccgcc accagagatt tttcagcgtt gagatgaaat ccgggcaggg
     6181 ggcgatgttt gccataattc cgcgggaaag ccccgagtaa aaatggttgt gcgagcagac
     6241 aattcccggc atcacaatcc gaccatgcat ctctttgtag ctggcatcgg ggtagcgttg
     6301 cgtcagggca tcgccgatag cgacaatcac gtcattttcg atagcgatat caacgccttc
     6361 ctgcactttc gccgggtgta actgcactgc ggtgacattc ttcagaatca acatgattac
     6421 acctccacgc ggcccagcag ataatgatga tgctggtgga catggctgat gatgcggcac
     6481 atatcgttca gctccggtgg tacgttgtta aactgacctt cgctgtcgat gtttaacacc
     6541 cagctttggt tattcagacg tactcgtacc cggcaatctt ccacaaggaa gcctgggttg
     6601 ctgctgttat caaagtcttg cgccaggctg aagacggtga ttttgtcttt gtatggttta
     6661 ccgttccacg gacagaactg agcgcagttg ccgcattcgt tacagtaagc gtcgaggtgc
     6721 agcgtctgga atctattctg gaagccaggg actgcaatgg agacgttggc gcggttcggg
     6781 cagacatcca cgcacttgct gcaaacgtag ttacattcaa ggcagcgagc agcttcctgc
     6841 gcgacaaacg catcacgatc gtcactgttc accagcgtga tagagatatc gcctttacgt
     6901 tgatagattt ccgccggatt gacgttgttc cagtatttat tgttctggtg ggaacggata
     6961 ttttcccgac taaggatggc atcggtcgcc cgacgcgcgg ttccgacagc agcgacaatg
     7021 gaggatggtc cgcgctgtac gtcgccgatc ataaagacgt cagtcagacg agtttcgcca
     7081 ttatggtcga cgtctggcca gccgtttttg tccagcggta cgcccatcgc attcagggct
     7141 tcagtatcct gctgttcacc gatggcggtg atcagactgt ctacatgcag tgttactgtt
     7201 tcgttggttt caaccggacg gcgacgacct ttctcatcgg gttcgccaag cgacataacg
     7261 cgcaaggtta aggtgccatc agcatcgaaa cattccggat tattcaggaa acggaactcc
     7321 acgccgtcgt gcaacgcttc ttcatactct tcgcgccatg cgggcatctc ttgcagtgaa
     7381 cgacggtaaa cgatcgttgc tttttctacg cctggaacgc gtaacgccgc acgagcgcag
     7441 tccattgcgg tgttacccgc cccgacaacg accacatgtt tgcccagctt gagcgctgta
     7501 cccttgttgt attcacgcag gaaggggagt gatttccaga cattttggtt gtcgcccgcc
     7561 agtttcacac cgctattttt atcagtgccg gtggcaatca gaacatagtg gaagccctga
     7621 ttttttaact gttcaacggt caaatcgggt gagcagccat actcaaattt cacgccgtga
     7681 gcggcaacaa aatcgatatc gtgctgaatt aactctgcag gaatacggaa ctgaggaatg
     7741 atatttttca ccacgccgcc agcattggct tcgcgttcaa acagcgtaac cggatggccc
     7801 gctctggcaa ggaagtaacc tgctgccaga cccgccggac ctgcaccaat cacggcaacc
     7861 ggatggcgtg aaccagaacc gacgggtttg tgccagcgtt gcttatattc atcccaacct
     7921 ttttccagcg cgactttttt cagttcgcgg atattcagcg cactgtcgta atccaggcgg
     7981 gtacagttgt attggcactg gtgatcgcaa atatgaccgg taatggcggg cagagcgttg
     8041 cgttggtaga tgagttccag cgcgtcggca tagcggtgtt cgccaagcag acggatgtat
     8101 tccggaatat cttgcttgat agcgcaggca gtaacacagg gggcaacgta gcaatcggtc
     8161 agcggcaggt cttctgccac ttcaatacgc tcttctggct tccagtgttt ctgggtgtat
     8221 tccatggtta acgcatctgc tgccagtctg ttcagtcgtt cgacgtcaac atggtcaagt
     8281 ccccaggcgt cggagccttc cagctcgcgc atgcaggcac ttaagcgcaa atagccgcca
     8341 ggtttcagca ggtcggttgc catagtaata gggcgaatac ctgtatcaaa aatatcgcgg
     8401 atagtcagct gactggcacc accggaataa gaaatgggca gtttgccgtc aaaggcgcga
     8461 gagagaactg ctgcaacatt gatggagagc gggaacagcg cacggcctga catatacatc
     8521 tcttcaccag gcagtgcgcc tttattgttg atggtgccga gagtgttagt cagttttacg
     8581 ccaaagccga gtgatttttc ttttgccagt gccatcaggc gttccagcat ttccagtgct
     8641 tgcgtcagct tgaggtcgtg atcaaatgac tcttctttta agcctatgta accgaaaccg
     8701 cagacatcga ggatctcacg aacacgcgcg tatcccagta aggtcgggtt aagtttcaca
     8761 aaggtgttga gccctttttc ttccagcatg tagcggcaaa tggcttcgat ttcatgcgga
     8821 ggacagccgt gcatggtgga gagggtgacg ccctgcacca tactggtggg gatgcgagcg
     8881 ggtaaggctt gcaagctttc gcgtttttcc tgcaatccgt ggcgggctaa aaatgcgtca
     8941 tcctggagta atttattcag cgtatcgcga tattgcgcga atttcggatg gtcagatgcg
     9001 tccatcatat tgtcgatgaa ctgttgcatt ggcggttgct taataccttc gaggttgtaa
     9061 ccgacgctca tattaaagat gaacgattta ccggaatcag aaggctggaa catcgcttcg
     9121 agaaggtgca gggcaaacca ggctttgagg tattcatccc aggctttaag cagggtaaat
     9181 tcggtagacc attcggtgtt aaagcactcg tcttcggcat cgatacaggg cttttccagc
     9241 tccaggcggt caagaatttg gacggttttt agttcgatga agcgtccgcc agtcagccag
     9301 gaagtgacaa tattttgcgc gagctgcgtg tgcgggccag cggcagggcc gacgggagtg
     9361 gcacaggttt caccgaagac gctaacagtt ttacctttta caggtgagta aaactgttgc
     9421 tcgggaatac caaagattga gcgttgttgt tggtattcat caaatatgcg cgtcaaaagt
     9481 tcctcaaacg gaatgggacg cataatatcc cccataaccc tctccttagc ttatacagat
     9541 atcattgagt gaccggtgtt gagaaatccg gtggtttagg gggatagagc aacaatcgca
     9601 ccactcttgc caggtttggc gggaaatata aaaaaatgtg aggcggctcg aaacttaaag
     9661 gctttttgtg aatgaactca caggtgccaa atgagaatta aaatcactcc tgaaaattat
     9721 tattgtcagc ccatttatca ctttttctct tttctcaaaa tcagtgattc cttatcatta
     9781 tgataaagag tgctggagag attaaatatt tgaacgcaat cgtttaacta cattttctaa
     9841 attttagtat accttttttg cgctgtaata aagtcgtccg gagtatcaat atctaaaatt
     9901 atttctgcat tttctatctc gacggaataa tgagctccca taaggagtgc ctgacgcata
     9961 ttggtgacat tgggtcgttg gattgcctgc atcaagcatg gttttgacac taaaatcgga
    10021 tggccgggga tgccattatg gagtggcagt attgcgccat catttcgtaa cgaccagatt
    10081 tttctaaaaa tatcgatggt gagggttggc atgtcaccgt gggtgagaaa acaatgttct
    10141 gtttgcactg cgggtactgc ggcctttact gatgttagta aaccctgcgc ataatctggg
    10201 ttgtggataa tagtgatatt gctctggttc gcataacgtt cgtgcagttc attaccacga
    10261 tagccggtga ctaaaataat tcggctacaa aactgcaacg catttttgat acttgtatca
    10321 agaattgtcc cctgttgcca gggtaacatc attttccatt gccccattct tgatgataat
    10381 ccggcagcgg taattataca gtcgatggct gacatagtgg ttccattatt tataggggct
    10441 aataacgcct gataattgcg ttacttcctg atggattaag ttggggataa tttatcccag
    10501 agaggtcata aagactcgtg aaaagtatag ttgacccatc ggcattagtc attgatttag
    10561 gtgcgcagaa acgtcccact gtgatttctg ttgttggtgc tggggggaaa accagcttgc
    10621 ttttttggct ggcagaactg ctccaggcta gcggcaggcg tgtgttaatc acgacgacga
    10681 cacatatgtt tatgccaacg tctcactggc ccgtggtttt ctgtcgtgat cccgccatgc
    10741 ttcctcatgc gtctcttaca tcccccattt cattttgttt tcacagctgg aaagcgaacc
    10801 agggaaaagt gcagggattt acgccagaag cgattgatgc actggtgcaa cgaccagagt
    10861 gtgacgtaat tctcattgaa gcagatggct cgcgtggaat gccgttaaaa gcgcctgatg
    10921 agcacgaacc ttgcataccc aaaagcagtt gctgcgtgat tgctgtgatg ggaggacata
    10981 ctttgggcgc gaaagtgagc acagaaaatg tccatcgctg gtcgcagttt gctgatatta
    11041 ccgggttaac acctgatgca accttgcaac tgagcgatct cgttgcgctg gttcgccacc
    11101 ctcagggggc gtttaaaaac gtaccgcaag gttgtcggcg agtctggttc attaaccgtt
    11161 tttctcaatg tgagaatgcg attgcacaaa gcgagctcct tcaaccgctg caacaacacg
    11221 acgtagaggc aatctggctg ggcgatatac aagaacatcc tgcaatcgcg cgcagatttg
    11281 tgaattagcg gcccgggtat tccgggttac tgaaaggata tccattgagg ttggtatgaa
    11341 tattttcaca gaggctgcaa aactcgaaga gcaaaattgt ccgtttgcga tggcgcaaat
    11401 tgttgatagc cgaggctcga ctccccgcca ttctgcacaa atgttagtgc gcgccgatgg
    11461 ttctatcgtc ggtacaattg gtggcggaat ggttgagcgg aaggtgattg aagagtcact
    11521 tcaggcattg caggaacgta agccgcgatt attccatgga cgtatggctc gtaacggtgc
    11581 ggatgctgtc gggtcagatt gtggaggtgc aatgtcagta tttatcagcg tccatggtat
    11641 gcgtccacgt ctggtgttga ttggcgcggg gcatgtcaac cgggcgatag cccagagtgc
    11701 ggcgctatta ggatttgata ttgccgttgc cgatatttat cgcgaaagcc tcaatcctga
    11761 actattccct ccatcaacca cgcttctcca tgctgagtcg tttggtgcag cagtggaagc
    11821 actggatatt cgccctgata attttgtcct gattgccacg aataatcagg atcgtgaagc
    11881 cctcgacaaa ctcattgaac agcccattgc atggttgggg ttgctggcaa gtcgccgcaa
    11941 ggttcagctt ttcctgcgtc aattgcgtga gaaaggcgtg gctgaagaac atattgcccg
    12001 tttacatgcg cccgttggtt acaacatagg tgcggaaacg ccgcaggaga tcgccatcag
    12061 cgtgttggca gaaatattac aggtgaaaaa taacgcgccg ggtgggctga tgatgaaacc
    12121 ttctcatcct tccggacacc agctggtggt gattcgcggt gcgggagata tcgccagtgg
    12181 tgtggcgcta cgtctgtatc atgcgggttt taaagtgatc atgctggaag tggaaaaacc
    12241 gacagtgatt cgttgtacgg tggcgtttgc ccaggccgtg ttcgatggcg aaatgacggt
    12301 cgaaggcgtc actgctcgcc tggcaaccag ctctgcggaa gcgatgaaac ttaccgaacg
    12361 cggattcatc cctgtgatgg tagatcccgc ctgttcattg cttgatgaac tgaaaccgct
    12421 ttgcgtggtg gacgctattc tggcgaaaca gaatttggga acgcgggcag atatggcacc
    12481 agtaacaatc gcgcttgggc cgggctttac tgcagggaag gattgtcatg cggtaattga
    12541 aacaaatcgc gggcactggc tcggtcaggt gatttactct ggttgtgcgc aggagaatac
    12601 cggtgttcct ggcaatatta tggggcatac cacccgacgg gtgatccgtg ctcctgctgc
    12661 aggcattatg cgatccaacg tgaaattagg cgatctggtg aaagagggcg atgtgattgc
    12721 ctggattggt gagcatgaaa ttaaagcacc gttgacgggg atggtgcgtg gcttgttgaa
    12781 cgacggcctg gcagtggtcg gtggttttaa aattggtgat atcgatcctc gtggtgaaac
    12841 ggctgatttc accagcgttt ctgataaagc ccgggcgatt ggcggcggcg tacttgaggc
    12901 gttaatgatg ttgatgcatc agggcgtgaa agcgacaaaa gaagtgctgg aagtggctta
    12961 aatgaaaatg gccggatggt attacccacc cggccttaaa attactgaca aatcaccgtt
    13021 ccggttttgc cttcaatccc ctctttcgct ttgctcaata cggtaatcag tgcttcacga
    13081 cctgcgcgag agcgagcaaa cgaggcggca gcttccactt taggcagcat agaacctttc
    13141 gcaaaatgac cttcttcgat aaagcgttca gcatcactta atgacaggcg atcgagccac
    13201 tgttcattct ctttaccgaa gttaatggcc actttttcta ccgcagtcag aatgatcagc
    13261 atatcggcat caatcatttc tgctaaacgg gcgctggccc agtctttatc gataaccgcg
    13321 ctggcaccac gcagatggtt accttcacga ataacaggaa taccaccacc gccaacggtg
    13381 atcaccacct ggcctgcatc taccagagct ttaaccgttt ctttttcaat aatatcaacc
    13441 ggttttggcg aggcaacaac acggcgatag ccgcgaccag catcttcttt cagagtgtaa
    13501 ccctgttttg tcagttgctc tgcttcttgc tcggtaaaga acgaaccgat cggcttggtc
    13561 gggttgagga atgccggatc gttagcgtcg acttcgacct gagtaaccag cgttgctacc
    13621 ggtttattaa tgccccgaga aagcagttct tctcttaagg cgttttgtag atcgtaacca
    13681 atataaccct ggcttaaggc aacgcagaca gacatcggca gcattggcga gtgcgcttca
    13741 gtttttgcag cagcttcaaa ggcctggtta atcatgccca cctgcggccc gttaccatga
    13801 gtgacgataa cttcatgtcc ttgggcaatt aaatcaacaa ttgcctgaga agtaattttt
    13861 accgctttca tttgtccggc caggtcatcg cccagcgcat tcccgcccag ggcgagaaca
    13921 attttcttac tcatttttcc tcactcatca ttcttgattg tgtatagatc cctgacagtg
    13981 gttagagcac gggagggaca aacggtttgc gtcgcaggaa acgacctcgc ccggctttgc
    14041 ctgtaaaggt gccgtcacag aaaatcgttt caccacggga taaggttctg acaatcgcgc
    14101 cctgacaggt aaaaccctcc catggcgagt agtcggcgtt gtcgtggaga tggcgatgct
    14161 gaatttgttg gctctgacgt gggtcgataa tcaccacgtc gccatcggaa ccgggcgcta
    14221 ataatccttt ttgcggccac aggccaaaca gcctggcggg cattgcgctg gttaattcaa
    14281 caaagcgttc cggtgttata cgtcccgtca tcacgccact ggaaaacagt aactgcatgc
    14341 ggttttccac accgggtaag ccatttgggc agcgactgaa atcgccttta gaaatttgca
    14401 ggcgttgagc catcgagaag gtgcagtgat cggtcgccac cacgtcaatc gcaccatcgc
    14461 tgatgccaca ccacagtttg tcctgctcgc gtacgttacg cagcggtggg ctaagaatga
    14521 acttcatgcc gtcttctgta tcgtaactgc gttcgtccaa caggagatat tgtgggcagg
    14581 tttcaaccca gactggctgg tgattcgcac gggcaagacg cagataatcc agacctaagc
    14641 cgttagacag gtgcacgata tagagcgggg cgttaccggc aatttgtgcc aggttaatca
    14701 tgcgggcgat ggcttccgct tcgcattcca gagggcgact caaggcatga tagcgcggcg
    14761 cggttaaccc tgcggcgata aattccgccc gcttgctggc gatagccgca tcattttccg
    14821 ggtgcacggt ggtcagcgcg ccggattcat gcagacggcg taatgcctgc aaaacctcgt
    14881 catcgttgag tttgtattga taggttaaat agagtttaaa actgctcagt ccttcctcga
    14941 ccatcatcgg gatttcgtcg aggattgcgt gattaatgtg ctggatcaca ccgtgaaagc
    15001 tgtaatcgat gaccgcttta tgggcggcat aaccacgata aacctccagt tgatggcgta
    15061 accgacagcc gtttgggcca aatcccatat ggtcaataat ggttgttgta ccgccacacg
    15121 cagctgcgcg ggtaccggta aaaaaatcat cacaactgcg cgcgatgccg acatcaatat
    15181 tgaaatgcgt atggacatcc acgccgccag ggaaaacgta acagccagtg gcatcaattt
    15241 cttcatacgg gagctgcggc gaaatattgt tgcccaactg gcgaacaatc ccgctttcaa
    15301 tcagcaaatc ctgtttggct tgtccatctg cgttaacgac agtgccgttt ttgatcaata
    15361 cgcgcatagc aaactccaaa aaccctccgg cgaaccggag gggaataagt gaagagtaat
    15421 tactctgttg ccagccagct taacgggatt gcagcgtaca tcgcggcaca ggtcaccagg
    15481 tgagatttcc aggttttttc gttaggtgca tgcgcttcag gttctttacc cgggccaaag
    15541 ccgatcaccg gaatgccgtg acggcccatg atagatacgc cgttagttga gaaggtccac
    15601 ttatcaacaa ccggcgcttt gccaaacagc ccttcgtagg cattcaccag tgctttaacg
    15661 gtgaagtgat cttcttccac tttccaggtc gggaagtagc attcggttgg gtaaaccagg
    15721 ccagtccagg acggacggtc gtagttgtac atagaaacaa ccgcgttagc tttctgtact
    15781 gcaggcaggg cgcggatttc gtccagcgcg ccttcccagg tttcgcccca ggtcagacgg
    15841 cggtcaatag agacggcgca gctatctgct acagcgcaac ggcttgggga tgtgaagaag
    15901 atttcagaaa cggtgagggt gcctttgccg aggaattcgt cataacccag acgttgggag
    15961 agttcttgta attcgccaag aatcggaccc attttgaaaa tggcgttgtc accgcgttct
    16021 ggcgcagaac cgtggcagct aacaccctga acatcaatac gaatttccat acgaccgcgc
    16081 tgaccacggt atatctggca gtcggttggt tcggtactga ccacaaattc cgggcgaatg
    16141 ccggattgtt caataatgta ctgccagcac agaccgtcgc agtcttcttc ctgcacagta
    16201 ccggtaacca gcagggtata ttcatcttcc agaccgaggt ctttaatgat tttaccggca
    16261 taaaccatag atgccatgcc gccttcctgg tcggaagtac cgcgaccacc gattagttca
    16321 tcagtttcca tgccttcgta cggatcgaag tcccagtttt tgatgttgcc aatgccgacg
    16381 gtatcgatat gagcgtccat tgccaccaga cgcgggccgt ggccgatata accgagaacg
    16441 ttgcccatcg ggtcgatttc aactttatcg aagccgactt tttccatctc ttctttaata
    16501 cgatgtacta cgcgtttttc gtcgcagctt tcactgggaa tagcaaccat gtcgcgcagg
    16561 aagcgagtca tgtccgcctg gtaatctttt gctttttcaa gaatcagttt gaatggaata
    16621 ttcttagcca ttatttttct ccagattttt tactccccgt tttgcaggga gcagttccaa
    16681 tagggtgatt aaggtgctac agcgtgtttg ccttcccaga caacttcgcg gtagtgcttc
    16741 acgtcggtgt cgccttcagt gctgataacc agcaccacgg catctttgtt cagcgccagt
    16801 ttttccatca ggctttgacg ttgcgggtga taatgaaccg ctgcgagaac gcccaaaccg
    16861 acagcgccgg attcaccgga gatgatgcgc gggtcgttgc cgtacggatt acccagcacg
    16921 cgcataccta atgcggcaac gctgtcctgg caggagatga attgggtggc gcagttacgt
    16981 aggatttccc agcccagcgg gttaggttcg ccacaggcca ggcctgccat gatggtggcc
    17041 atatcaccgc caacgttgac gatgtcgcct ttgacgccgg agcgataaat acagtcagct
    17101 ttgtcaggtt caacaataat gctgtgcaga ttttgcgggc tatagacgtc gaccagataa
    17161 cccagcacac caccggccat tgctccgaca ccggcttgca gcagaacgtg cgtcggggtt
    17221 acgcccattt cacgcatttg ctcgacggct tcatctgcca gggttgcgta gccttgcatg
    17281 atccaggttg ggattttggt gtaaccttcc catgccgtgt cctgtaccac ttcccagccg
    17341 tgctgctgcg cgtgttgcat ggtcaggcga acggtatcgt catagttcat atctgtgacg
    17401 atgcactcgg caccgaggtt cagaatggcg tcaacgcgtt cctgagcaga acctttcggc
    17461 atgtaaatca ccgcattctg tccgagttgc tgcgctgccc acgccacacc gcgcccgtgg
    17521 ttgccgtcgg tggtggtcgc gaaagtcatt ttttcgccga tggcattttt caggtgctca
    17581 aatgacagcg tttcgatatc aagatgatat ttttcacaca ataattgagc gatggcgtac
    17641 gcaccgccga gcattttgaa ggcgttcaga ccgaatcgtt ttgattcgtc tttgacaaga
    17701 attttcttca caccaaaaag gtttgcgaga tcgtccagcg cacaaagcgg tgttgggcga
    17761 taaccagcta ttttctggtg gaactggcgc gccagtttgg cctggctttg cgaaaagagc
    17821 ggtgatgttt cgccgttgaa aaatttgtta tcggcgatat caatcttcaa tgagaaaacg
    17881 gacatatcct atccttttgg cctctggaaa tagagggccg accagctgat cggcccgagg
    17941 ggttatttca cgcgttcttg cgcttctttc agcagttgct cgagcagtgc acctggtttg
    18001 gcgtatttac gggacaggat catcgcggcg atgatataag gcttccagct ggcttctttg
    18061 taggttgcga tacggtattt ttcgaatacg ccttcagtca cttcaccttc tttacaggat
    18121 acgccgctga tatcagctgg caggcagtgc atgtacaggg cttcgccatc acgggtcagt
    18181 tccatcatct cttcagtaca atgccagtct ttgtgttgcg cgttctgtgc cagacactgt
    18241 ttttccagtg cttttaagcc ttcgtgatcg ttagcgcgca gcaattcggt acgctgttcc
    18301 atcactttgt aaggtgccca tgacttcgga taaacgatgt ctgcatcttt gaacgcttct
    18361 tccatgctgg tgacctgacg gaagctaccg ccagatgctt tagcattgtt tttcgccact
    18421 tcaaccacat ccgggatcag gtcgtagcct tccggatggg ccagggtgac atccataccg
    18481 aagcgagtca tcagaccgat gatgccttgt ggtacagaga gcggtttgcc atagcttgga
    18541 gagtaggccc aggtcatggc gattttttta cctttcaggt tttccagtga accaaagtgt
    18601 tcacgtaacc acgcgaggtc agccattgac tgagtcgggt ggtcaatatc gcattgcagg
    18661 ttcactaaag ccggacgctg tggcagtaca ccctgcttgt aaccgtcatc aagtgcagcg
    18721 ccaacttcac gcatataggc gttgcctgcg cccagaaaca tatcgtcgcg aataccaata
    18781 gcgtcggcgc agaaggagat catattggcg gtttcacgca cggtttcgcc gtgagcgatt
    18841 tgtgatttgc cttcgtcgag atcttgttgt gcaaggccga gcaggttaag cgcggaagca
    18901 taagagaagc gggtacgggt ggagttgtcg cggaatacgg aaatacctaa tccactatta
    18961 aagactttgg ttgagatgtt ttcagcacgc agtgctttta atgctgcggc aacgtccagt
    19021 acttgtttca gttcatctgg cgtctgttcc cacgttaaca aaaaatcttt ctcgtgaagg
    19081 tgagaggtca gcgaattgat atccttaatc agctcattaa cagttttcat cataaagtcc
    19141 cggtagtgga atgacaggca aagtggttta tttcactgtg acttgccaaa gtgattggtg
    19201 ttttcacagc tatacctggg actaacaata agtgtgccag aattatccac ggggctgcaa
    19261 aagactaatt tgacggataa tgtgtggggt tgatcacaaa ttgatgccag cttccggttg
    19321 tttgtaaaat acgaaaacgt ttggcttttt ttatcgcgtt atttatttgc tgctaagtat
    19381 cagaaataag ataaagggac aggctatctc tcttcagttt gataaactca ccgccgtaat
    19441 tctcatattg atatagaaat gtgatatctc ttccataatt tcattagaaa atgataaaaa
    19501 tcttatgttt ttatcaaagc caatttcgcc tgagttaata tcatcatgat ctgtgaacca
    19561 tcaacgtctt caatgatcga cttttaagta agtctggaag gtaaagctat ggagcttgct
    19621 actacgcagt cagtattgat gcaaattcaa ccgacaattc agcgttttgc cagaatgctt
    19681 gccagcgttt tgcagcttga ggttgagatc gttgatgaaa acttgtgtcg cgtcgccgga
    19741 acgggcgcgt atgggaagtt tcttggtcgc cagttgagcg gcaactcacg cctgctccgc
    19801 cacgtcctgg aaacgaaaac tgaaaaagtt gtgacacagt ctcgcttcga tcccctttgc
    19861 gaaggttgcg atagtaaaga aaattgccgc gaaaaagcat ttctgggtac gcctgtcatt
    19921 ttacaggatc gttgtgttgg ggtgataagt ttgattgccg ttacccacga gcaacaagag
    19981 catatcagtg ataatttacg cgaattttct gattatgttc gccatatatc caccattttt
    20041 gtttcgaaac ttctggagga tcaggggcca ggagataaca tcagtaaaat attcgcgacc
    20101 atgatcgata atatggatca gggcgtatta gttgttgatg atgaaagtcg ggttcagttt
    20161 gttaatcaga ctgccttaaa aacacttggt gttgtacaaa ataatattat tgggaaacct
    20221 atccgtttca gaccattaac atttgagagt aattttactc atggacatat gcagcatatt
    20281 gtttcgtggg acgataaaag tgaattaatc attggtcaat tgcataacat tcagggccga
    20341 caattatttt taatggcatt tcaccaatcg cataccagtt tttctgtagc aaatgcacct
    20401 gatgaaccac atattgaaca attggttggc gagtgccgtg ttatgcggca attaaaacga
    20461 ctcattagcc gtattgcacc cagcccatcc agcgttatgg tggttggtga aagcggcacg
    20521 ggtaaagaag tcgtcgcccg agcaatccat aagttgagcg gaagacggaa taaacccttt
    20581 attgctatca actgtgccgc gattccggag cagcttctgg aaagcgaact gttcggttat
    20641 gttaaaggcg catttactgg cgcttctgcc aacggtaaaa cagggttgat tcaggcggcg
    20701 aatacgggca cgctgtttct cgatgaaata ggtgatatgc cattaatgtt gcaggctaaa
    20761 ttactgcgcg ctattgaggc gcgtgaaatt ctgccgattg gtgccagtag cccaatacaa
    20821 gtcgacattc gcatcatttc tgcaactaat cagaatttgg cccagttcat tgccgaaggt
    20881 aaattccgcg aagatctctt ctaccgactt aatgttatcc cgataactct gccaccgctg
    20941 cgtgaacgtc aggaagatat tgaactattg gtgcattact ttttacatca gcatacccgt
    21001 cgtctgggat cggtttatcc tggcattgct cccgatgtcg tcgaaatatt gcgtaagcat
    21061 cgttggcccg gaaacctgcg cgagttaagc aatttgatgg aatatctggt taacgtagtt
    21121 ccttcaggtg aagttatcga cagcacgcta ttgccgccaa atctgctgaa taatggcaca
    21181 acggagcaaa gtgatgtaac agaggtcagt gaggcgcacc tgtcactcga tgatgcgggc
    21241 ggcacggcgc tggaggagat ggaaaagcaa atgatccgcg aggcgctttc acgtcataac
    21301 agcaagaagc aagttgctga tgaactgggc atcggcattg ctacgctcta tcgcaagatt
    21361 aagaaatatg agttgttaaa catataacct cagtgaatcc ggcctgaatt caggccggat
    21421 atccttttac ttcgttttct cgcaatccag aactgtattt acaatcatct gataccccgt
    21481 gcagcgacaa agatttcccg ccagtccgcg acgaatttcc gtaatggtta atggcttctc
    21541 gcgtggtttc gccagcattg ccgtggtagc cataatcagg ccaggcgtac aaaacccgca
    21601 ctgcactgcg ccggatttcg cataagcctg ctgaacatga gaaagttttc cgcctttcgc
    21661 ttcaccttcc agcgtgcgga tctcttttcc ttcagcccag gcggcaaggt ataagcaact
    21721 gtctattgct gtgccgtcga ccaacaccgt acaggcacca cattcaccca cgcagcaccc
    21781 ttgtttgaca cttagcagtc cttgttcgcg gagtaattcc gagagcggcg tgcctggtgc
    21841 ggcgtgaagc tgaaaaggca tcccgttaat ggtgcattcg atggtaattg tttcgctgtg
    21901 attcattgca attttccccc cgccgcggcg acggcttcgc taatcacttt tttggtcatc
    21961 gtctggatga gatgcagacg aaactcttta ctggcccgcc atgaagaacg cggggcgaca
    22021 tcttgcagga cagattcgct gatagcttcc agcgtttgca ggtttaatgg cgcattttgt
    22081 gcagtctgtt cggcatgttg gcagcgaatc ggcgttggcg cggcaacacc aaatgccagg
    22141 cgtaattcgc tgaaattgcc gttatccagt cggcaatgtg cggcgcagcc aatcgttgaa
    22201 atatccattg cgtcgcgcat ggcatattta aaatgcgcgc tgcccgcgtg ttctttcggc
    22261 tgtggcggaa aatgaaaggc gacgaggatt tcgtcatgct caagagacac tttgcccggc
    22321 ccggtgtgaa agccattaat cgggacgaaa cgaacaccgc gcggggagtg gatctccagt
    22381 ttcgcgtcat aaattagcgt tggcgtggca gaatctgcgc tggtggcacc gttgcaaata
    22441 tttccaccgt aggtagcgac gttacggatc tgcggtccag caatggacgt ggccgcagca
    22501 cataacgccg ggagatgacg ttgagttata ggatcttcta ttagctgggt aaatgtcgtt
    22561 gcagagccga tacgtagcga gccatcttcc gccagcgtaa ttccccgcag ctccgccaga
    22621 ttatgaatat caacaatatg gcgataacgg tcattgtgat ggtggagctg aatcagtacg
    22681 tcagtgccac cggcgagcag tttggcctgc gggttgtcag ccagcaggtt gatggcatcg
    22741 gcaagggttg ctgcgcgatg gtaagaagca aaatcaaaca tgatgttatc ctcaaatcaa
    22801 tcctgccaga tggaactctt catataaccg ttttggcgtc agcggcagtg tattgattgc
    22861 aacaccggta gccatcttca ccgcgttacg aatagcagcg gcaacaggaa ttattggtgg
    22921 ctcacccagt gacttatgtc cgtatgcgga ttgcggctca ttgatttcga cgaacgcgct
    22981 ttccagttgt ggcagatccg gcatggtcgg cattttgtaa tccagcagat tggggttacg
    23041 gaccacgccg cttttagcat cgatgatcat ctcttcaaat agcgcccagc caatgcccat
    23101 tcccattccg ccgtgtacct gaccttctgc cagcagtgga ttaagaatat gccctgaatc
    23161 atgaacgttg aggatgcggt tgatgatgac tttgcacagc gcaatatcga ccgtcagatc
    23221 aacaaaggta cagccaaacg ccggtgggtt agtggtggtt ttgatggagc tttcagcaga
    23281 gagctgcccg ccgcgttcag ggtggtagaa agcgtccatc gccaaatctt ttaacgacat
    23341 taacggctct tccggtcgtt caaccagcac gatatggcct tttatcaggg tcagattcat
    23401 cgctgactga tgtagcatga ctgcggcgtg agcgatgatt ttctctttta ataatagtgc
    23461 cgcactgcgc agcgcaggcg cggcaacata gctctggcgt gaggcaaatg cgccgggatc
    23521 gaacggcgta acgtcggtat cttgagttga aataacgcga acgtcgctga ccggaacccc
    23581 cacggtttct gccaccattt gcgagaagac ggtgtcggca ccctgaccga tttccgtcgc
    23641 gccgctttgc acgttgatgg ttccatcctg attcatcaga aggcgcgcgc ctgctatttc
    23701 tacgccgaca ggccaggtgt tagaggtgta gctaaaacag gcgacgccaa cgccgcggcg
    23761 caaattgcct tgctggttct ggcattctgc acggcgtttt tcccattcaa agattttccg
    23821 gcctttttca agacactccg gcaaccctgc gctgtaaata cgtttgcccg tgagcggatt
    23881 agcatctcct tcgcgggcgg cgttgcgtaa acgaatttca acaggatcaa tacctaacgc
    23941 tgtcgcggcg tcatcaagca tagactcaac ggcaaatacg acttgtggcg cgccataacc
    24001 acgcatcgca ccagccgagg ggaggttggt atagcaggtc tttgaactgt aagcgtaggc
    24061 acaacgagga taaaggtaag cgactttatt cccccccgca gaagcgatgg agtgcccgtg
    24121 agatgcataa gcgccggtgt tagacagaac atccagacta taacctttca atgttccgtc
    24181 gcggttcacg cccatttgcc cgtcaatggt aaaagcgtgg cgggtacggg ttgcgaggaa
    24241 acactcttca cggctaaggg aaactttcac cggaatgccg ccaagcttgc tggtcaggaa
    24301 tgccgccatt ggctcttcca gtacatcctg tttattacca aaaccgccac cgacaaacgg
    24361 tttgatgact cgtacgcatg accagggaat atccagcgcc tgaccaacca cgcggcgaac
    24421 aatgtgcggg atctgggtgc tggaaacgat ggtaattcgc gagtcatcct ccatccacgc
    24481 cagcgatgtt acgctttcca tgtgacaatg ttgaataacg ggggtctgat agtgcccctg
    24541 tacctggtag tcggcggcat cgattgtttg ttggacatta cccgtcgaca tcgtgctttg
    24601 tttcagtaaa ttgccaccgt tatggattgg tgcagcgtct tctgccagcg ccgcttctgg
    24661 cgtggtgata acgggtaatt cttgccactc aatgctgacc aattgcgccg ctttttctgc
    24721 cgtgagttca tcgcgggcca cgacgatggc aacggcgtca ccatgatgac gaacatggcg
    24781 agttagcagt gcgcgatcgg cggtatcgcg cttgttttcg tcaagtgtcc aggcatgccc
    24841 agcagtagca aatggaatat caggcacatc ttcccaggta aaaatcgcca gtacgcccgg
    24901 caaacttctg gcttgttcat cattaatact tacggcataa ccatgtgcga tagggctacg
    24961 tacatatttc gcataacaca tgcccgccat aacataatcg tcagtatatc gtgcccgccc
    25021 ggtgacctta gcaatggcat cgacgcgcat gcatgattca cccgtagcgg ttgcttcccg
    25081 cgcttccata gaaatcccct cgatttgaac atttggttct tatggcaaag atttagtcta
    25141 agcaggcaag atttacgcca gaaacgacga taagcgttag gggaggtagg aagtgtgatg
    25201 acgttaaaaa aacacagata tgatacgaaa caggactctg aataggggca gtgatacgta
    25261 tcaatatgag tggcgataaa atcaatgtga taaattggga ttattacgca tcaggatggg
    25321 aaatagggta aaaagtcagg aagttcgata cctctacagc gaatattttg ctgatgatac
    25381 ttccctttgc caaatgaaat taacctcttt ctctattacc acgtttttcc agaagcaaga
    25441 gattgggtat caagaggctg gctgctatga taaggcgtct tgttttttaa gcgaggaaag
    25501 attttgagtg cgggacgcct gaataaaaaa tctctgggta tcgtgatgtt gttatcggtt
    25561 ggactgcttt tggcgggctg ttcgggtagc aaatcatccg atacaggaac gtattccggc
    25621 tccgtttaca ccgtgaaacg gggggatacg ctatatcgta tttcgcgcac cacgggaacc
    25681 agcgtaaaag aactggcgcg actgaacggc atttcccccc cttacaccat tgaagttggt
    25741 cagaaactaa aactaggtgg ggcgaaaagt agcagtagta cacgtaaatc aaccgccaaa
    25801 tcaacgacca aaaccgcatc ggttacaccg tcatcagcgg taccgaaatc ttcctggccg
    25861 ccagtagggc aacgttgttg gttatggcca acgacaggga aagttatcat gccgtattcg
    25921 acagcagatg gcggcaataa agggattgat atctcagctc cacggggtac acctatttac
    25981 gccgcgggtg caggaaaggt ggtgtatgtg ggcaaccagc tgcgtggcta cggtaatctc
    26041 atcatgatta aacacagtga agattacatt acggcttacg cccataatga cacgatgctg
    26101 gtaaataatg ggcaaagcgt gaaggctggg caaaaaatcg ccactatggg gagcacggat
    26161 gcggcatctg ttcgcctgca tttccagatt cgttaccgtg caacggcaat tgatccgcta
    26221 cgttacttgc cgccgcaggg cagcaagcca aaatgctgat ggcgaattaa tcagcagtca
    26281 gcagcgcggc acttgctaag gagagcgtaa ggtttataat gccttacgca tctcgaagcg
    26341 ggcgtagttc aatggtagaa cgagagcttc ccaagctcta tacgagggtt cgattccctt
    26401 cgcccgctcc aatttatctt cacctgatca atctgccatt tttgctgtat ctgattttct
    26461 atattatctt aattcaatcg cttcagactt ttcgcaatcg ccgtaatact tccccatttt
    26521 gttgtaaata aaaagcgttt acgcaatgca atccttttgt aacaacccag gtaaaacacc
    26581 ttattttcaa gttgttaaat aagtggttat ctacgctttt aacaaacgat tgatggaata
    26641 ttttatgaaa gggaaatctg cattaactct tctgctcgct ggtatatttt cgtgcggcac
    26701 atgccaggcg acaggggcag aagtgacgag tgaatctgta tttaacattc ttaattccac
    26761 gggggcagca acagataaaa gttatttatc gttaaatcca gataagtatc ctaattatcg
    26821 tcttttgatt cactcagcca aattacaaaa tgaaataaag agccactata ccaaagacga
    26881 aattcaagga ttgctaacat taacagaaaa cacacgaaag ttaacgttga cggagaaacc
    26941 ctggggaacg tttattcttg cttctacttt cgaagatgac aaaacagcgg cagaaaccca
    27001 ctatgatgct gtctggctga gggatagttt atggggctat atggcattag tatcagatca
    27061 gggaaatagt gtagccgcaa aaaaggttct gctcaccctg tgggattata tgtctacgcc
    27121 cgaccagatt aagcggatgc aggacgtcat tagcaacccc aaacgactgg atggagttcc
    27181 cgggcaaatg aatgttgtgc atatccgatt tgacagcaac tcccccgtga tggcagatgt
    27241 gcaggaagaa ggcaagccgc agctgtggaa ccataaacaa aatgatgcgt taggtcttta
    27301 tcttgatctc cttatacaag caatcgacac tgatacaatt aacgctgaag attggcaaaa
    27361 aggtgaccga ttaaaatcgg ttgcgctgct gattgcttat ctggataaag ccaatttcta
    27421 tgttatggaa gattccggag catgggaaga agatgcccga ttaaacacat cttccgttgc
    27481 actggtgacc tctggactgg aacgtttgtc gaacttactc tcgaagaaag actctgtttt
    27541 tgtctctgat ttactacgcg aagctaaagc caatgaactg gatgaacctc tttcaacaac
    27601 gaggttgaac cacctcatag ataaaggtta tgaaagaata acgttacagc ttgatttagg
    27661 gggagaatcc ccaggttatc tggaaaaaga taaacattac agagaagccg atgcggcttt
    27721 acttaatgtt atttatcctg caaatcttgc aaagataaac accagaagaa aagagcaggt
    27781 tctaaaaata gttaaaaaac tagcaggtcc gtatggtata aaaagatacg agaaggataa
    27841 ttatcagtcg gcaaattttt ggttcaatga tattaaaacc gataccgatc aaaattcaca
    27901 tgcgaaaaga gaaaagagct tcattccatc aacagaagca gaatggtttt ttgactcatg
    27961 gtatgcaaaa tcagcagcaa ttgtttataa agaatcaaga aaggaagagt atttgaatga
    28021 ctcagtgcaa tttatgaata gatcattggc ccaaataaca ggcgagaata tgattggtgc
    28081 aaatggcagg agtgtacctg aaatggcact tcccgaaagc tataactata tccacaagtc
    28141 gggaactttg catgaagcgc caagccctat cattccgcta aattggtcga aagcttcaat
    28201 gactctcatg ttgaaagaga tgtccaacct tatcaatgat gagggaatta aatagttttc
    28261 ataatgagtt acagcacaac gttgggtatt gactgagcaa gatgaacgac aaggacaacg
    28321 acatcagcct tatgaggagc aagaaaatga aagcaaattc gaaaacgatc agaaggatga
    28381 aagttaatgt tcggtctgag gaaagtaaat cgaaacactc atacgtttga aaccactttt
    28441 caaaattgga aagaaaatgg cgaagatgtt gcattattaa tgcccgaatt tagtgctaaa
    28501 tggttaccga tagcagaaga gagtggcagc tggtctggat gggtattgct tggagaaata
    28561 tttcccttaa tttcatctga gctcgctggg atggctttaa tgccagaaac ggaaaggtta
    28621 ataggggaat ggctcagttt atccagttcc ccgttaaatc taaagcatcc tgaactaaaa
    28681 tataatcgtt tgcacgtagg taaagtattt gatggagtat tgagccctgc tcaaccacta
    28741 ataagaatat gaacagggga attgaatctt tggttagata aagtcacagt ctgccaatac
    28801 ggaaacgctc cagtgttaga caaaaaatca ttatattggt ccattcattt tgtaattgga
    28861 tttagtaaaa catgttacag aagtcttgtt gatattgaag ttggtgatgt tttattaat
//
LOCUS       DAPGUL010000053        28832 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.053, whole genome shotgun sequence.
ACCESSION   DAPGUL010000053 DAPGUL010000000
VERSION     DAPGUL010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 28832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28832
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.053"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            9..638
                     /gene="sxy"
                     /locus_tag="RHX21_002489"
     CDS             9..638
                     /gene="sxy"
                     /locus_tag="RHX21_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRP-S regulon transcriptional coactivator Sxy"
                     /protein_id="HDV1987653.1"
                     /translation="MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVS
                     DGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLNYYRVDESLWRNQLKLVRLSKYS
                     LDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
                     SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE"
     gene            complement(601..2763)
                     /gene="yccS"
                     /locus_tag="RHX21_002490"
     CDS             complement(601..2763)
                     /gene="yccS"
                     /locus_tag="RHX21_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309071.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01666 family membrane protein"
                     /protein_id="HDV1987654.1"
                     /translation="MAFMLSPLLKRYTWNSAWLYYARIFIALCGTTAFPWWLGDVKLT
                     IPLTLGMVAAALTDLDDRLAGRLRNLIITLFCFFIASASVELLFPWPWLFAIGLTLST
                     SGFILLGGLGQRYATIAFGALLIAIYTMLGTSLYEHWYQQPMYLLAGAVWYNVLTLIG
                     HLLFPVRPLQDNLARCYEQLARYLELKSRMFDPDIEDESQAPLYDLALANGQLMATLN
                     QTKLSLLTRLRGDRGQRGTRRTLHYYFVAQDIHERASSSHIQYQTLREHFRHSDVLFR
                     FQRLMSMQGQACQQLSRCILLRQPYQHDPHFERAFTHIDAALERMRDNGAPADLLKTL
                     GFLLNNLRAIDAQLATIESEQAQALPHNNDENELADDSPHGLSDIWLRLSRHFTPESA
                     LFRHAVRMSLVLCFGYAIIQITGMHHGYWILLTSLFVCQPNYNATRHRLKLRIIGTLV
                     GIAIGIPVLWFVPSLEGQLVLLVITGVLFFAFRNVQYAHATMFITLLVLLCFNLLGEG
                     FEVALPRVIDTLIGCAIAWAAVSYIWPDWQFRNLPRMLERATEANCRYLDAILEQYHQ
                     GRDNRLAYRIARRDAHNRDAELASVVSNMSSEPNVTPQIREAAFRLLCLNHTFTSYIS
                     ALGAHREQLTNPEILAFLDDAVCYVDDALHHQPADEERVNEALASLKQRMQQLEPRAD
                     SKEPLVVQQVGLLIALLPEIGRLQRQITQVPQETPVSA"
     gene            complement(2773..3219)
                     /locus_tag="RHX21_002491"
     CDS             complement(2773..3219)
                     /locus_tag="RHX21_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HDV1987655.1"
                     /translation="MRTVLNILNFVLGGFATTLGWLLATLVSIVLIFTLPLTRSCWEI
                     TKLSLVPYGNEAIHVDELNPAGKNVLLNTGGTVLNIFWLIFFGWWLCLMHIATGIAQC
                     ISIIGIPVGIANFKIAAIALWPVGRRVVSVETAQAAREANARRRFE"
     gene            3342..5396
                     /gene="helD"
                     /locus_tag="RHX21_002492"
     CDS             3342..5396
                     /gene="helD"
                     /locus_tag="RHX21_002492"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase IV"
                     /protein_id="HDV1987656.1"
                     /translation="MELKATTLGKRLAQHPYDRAVILNAGIKVSGDRHEYLIPFNQLL
                     AIHCKRGLVWGELEFVLPDEKVVRLHGTEWGETQRFYHHLDAHWRRWSGEMSEIASGV
                     LRQQLDLIATRTGENKWLTREQTSGVQQQIRQAMSALPLPVNRLEEFDNCREAWRKCQ
                     AWLKDIESARLQHNQAYTEAMLTEYADFFRQVESSPLNPAQARAVVNGEHSLLVLAGA
                     GSGKTSVLVARAGWLLARGEASPEQILLLAFGRKAAEEMDERIRERLHTEDITARTFH
                     ALALHIIQQGSKKVPIVSKLENDTAARHELFIAEWRKQCSEKKAQAKGWRQWLTEEMQ
                     WSVPEGNFWDDEKLQRRLASRLDRWVSLMRMHGGAQAEMIASAPEEIRDLFSKRIKLM
                     APLLKAWKGALKAENAVDFSGLIHQAIVILEKGRFISPWKHILVDEFQDISPQRAALL
                     AALRKQNSQTTLFAVGDDWQAIYRFSGAQMSLTTAFHENFGEGDRCDLDTTYRFNSRI
                     GEVANRFIQQNPGQLKKPLNSLTNGDEKAVTLLDESQLDALLDKLSGYAKPEERILIL
                     ARYHHMRPASLEKAATRWPKLQIDFMTIHASKGQQADYVIIVGLQEGSDGFPAAARES
                     IMEEALLPPVEDFPDAEERRLMYVALTRARHRVWALFNKENPSPFVEILKNLDVPVAR
                     KP"
     gene            complement(5428..5886)
                     /gene="mgsA"
                     /locus_tag="RHX21_002493"
     CDS             complement(5428..5886)
                     /gene="mgsA"
                     /locus_tag="RHX21_002493"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415483.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HDV1987657.1"
                     /translation="MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYA
                     TGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDV
                     KALLRLATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLADRLK"
     gene            complement(5982..6644)
                     /locus_tag="RHX21_002494"
     CDS             complement(5982..6644)
                     /locus_tag="RHX21_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2057 family protein"
                     /protein_id="HDV1987658.1"
                     /translation="MKTGIVTTLIALCLPVSVFATTLRLSTDVDLLVLDGKKVSSSLL
                     RGADSIELDNGPHQLVFRVEKTIHLSNSEERLYISPPLVVSFNTQLINQVNFRLPRLE
                     NEREANHFDAAPRLELLDGDATPIPVKLDILAITSTAKTIDYEVEVERYNKSAKRASL
                     PQFATMMADDSTLLSGVSELDAIPPQSQVLTEQRLKYWFKLADPQTRNTFLQWAEKQP
                     SS"
     gene            6817..7230
                     /locus_tag="RHX21_002495"
     CDS             6817..7230
                     /locus_tag="RHX21_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HDV1987659.1"
                     /translation="MKETDIAGILTSTHTIALVGASDKPDRPSYRVMKYLLDQGYHVI
                     PVSPKVAGKTLLGQQGYGTLADVPEKVDMVDVFRNSEAAWGVAQEAIAIGAKTLWMQL
                     GVINEQAAVLARDAGLNVVMDRCPAIEIPRLGLAK"
     gene            complement(7275..7592)
                     /gene="hspQ"
                     /locus_tag="RHX21_002496"
     CDS             complement(7275..7592)
                     /gene="hspQ"
                     /locus_tag="RHX21_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein HspQ"
                     /protein_id="HDV1987660.1"
                     /translation="MIASKFGIGQQVRHSLLGYLGVVVDIDPVYSLSEPSPDELAVND
                     ELRAAPWYHVVMEDDNGLPVHTYLAEAQLSSELQDEHPEQPSMDELAQTIRKQLQAPR
                     LRN"
     gene            complement(7650..8840)
                     /gene="rlmI"
                     /locus_tag="RHX21_002497"
     CDS             complement(7650..8840)
                     /gene="rlmI"
                     /locus_tag="RHX21_002497"
                     /EC_number="2.1.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415487.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (cytosine(1962)-C(5))-methyltransferase
                     RlmI"
                     /protein_id="HDV1987661.1"
                     /translation="MSVRLVLAKGREKSLLRRHPWVFSGAVARMEGKASLGETIDIVD
                     HQGKWLARGAYSPASQIRARVWTFDPSESIDIAFFSRRLQQAQKWRDWLAQKDGLDSY
                     RLIAGESDGLPGITIDRFGNFLVLQLLSAGAEYQRAALISALQTLYPECAIYDRSDVA
                     VRKKEGMELTQGLVTGELPPALLPIEEHGMKLLVDIQHGHKTGYYLDQRDSRLATRRY
                     VENKRVLNCFSYTGGFAVSALMGGCSQVVSVDTSQEALDIARQNVELNKLDLSKAEFV
                     RDDVFKLLRTYRDRGEKFDVIVMDPPKFVENKSQLMGACRGYKDINMLAIQLLNEGGI
                     LLTFSCSGLMTSDLFQKIIADAAIDAGRDVQFIEQFRQAADHPVIATYPEGLYLKGFA
                     CRVM"
     gene            8935..9213
                     /gene="yccX"
                     /locus_tag="RHX21_002498"
     CDS             8935..9213
                     /gene="yccX"
                     /locus_tag="RHX21_002498"
                     /EC_number="3.6.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HDV1987662.1"
                     /translation="MSKVCIIAWVYGRVQGVGFRYTTQYEAKRLGLTGYAKNLDDGSV
                     EVVACGEEGQVEKLMQWLKSGGPRSARVERVLSEPHHPSGELADFRIR"
     gene            complement(9210..9539)
                     /gene="tusE"
                     /locus_tag="RHX21_002499"
     CDS             complement(9210..9539)
                     /gene="tusE"
                     /locus_tag="RHX21_002499"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309080.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusE"
                     /protein_id="HDV1987663.1"
                     /translation="MLIFEGKEIETDTEGYLKESSQWSEPLAVVIAENEGISLSPEHW
                     EVVRFVRDFYLEFNTSPAIRMLVKAMANKFGEEKGNSRYLYRLFPKGPAKQATKIAGL
                     PKPVKCI"
     gene            complement(9630..10289)
                     /gene="yccA"
                     /locus_tag="RHX21_002500"
     CDS             complement(9630..10289)
                     /gene="yccA"
                     /locus_tag="RHX21_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsH protease modulator YccA"
                     /protein_id="HDV1987664.1"
                     /translation="MDRIVSSSHDRTSLLSTHKVLRNTYFLLSLTLAFSAITATASTV
                     LMLPSPGLILTLVGMYGLMFLTYKTANKPTGIISAFAFTGFLGYILGPILNTYLSAGM
                     GDVIAMALGGTALVFFCCSAYVLTTRKDMSFLGGMLMAGIVVVLIGMVANIFLQLPAL
                     HLAISAVFILISSGAILFETSNIIHGGETNYIRATVSLYVSLYNIFVSLLSILGFASR
                     D"
     gene            complement(10496..10583)
                     /locus_tag="RHX21_002501"
     tRNA            complement(10496..10583)
                     /locus_tag="RHX21_002501"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10547..10549),aa:Ser,seq:tga)
     gene            11010..12128
                     /gene="hyaA"
                     /locus_tag="RHX21_002502"
     CDS             11010..12128
                     /gene="hyaA"
                     /locus_tag="RHX21_002502"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 1 small subunit"
                     /protein_id="HDV1987665.1"
                     /translation="MNNEETFYQAMRRQGVTRRSFLKYCSLAATSLGLGAGMAPKIAW
                     ALENKPRIPVVWIHGLECTCCTESFIRSAHPLAKDVILSLISLDYDDTLMAAAGTQAE
                     EVFEDIITQYNGKYILAVEGNPPLGEQGMFCISSGRPFIEKLKRAAAGASAIIAWGTC
                     ASWGCVQAARPNPTQATPIDKVITDKPIIKVPGCPPIPDVMSAIITYMVTFDRLPDVD
                     RMGRPLMFYGQRIHDKCYRRAHFDAGEFVQSWDDDAARKGYCLYKMGCKGPTTYNACS
                     STRWNDGVSFPIQSGHGCLGCAENGFWDRGSFYSRVVDIPQMGTHSTADTVGLTALGV
                     VAAAVGVHAVASAVDQRRRHNQQPTETEHQPGNEDKQA"
     gene            12125..13918
                     /gene="hyaB"
                     /locus_tag="RHX21_002503"
     CDS             12125..13918
                     /gene="hyaB"
                     /locus_tag="RHX21_002503"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase large subunit"
                     /protein_id="HDV1987666.1"
                     /translation="MSTQYETQGYTINNAGRRLVVDPITRIEGHMRCEVNINDQNVIT
                     NAVSCGTMFRGLEIILQGRDPRDAWAFVERICGVCTGVHALASVYAIEDAIGIKVPDN
                     ANIIRNIMLATLWCHDHLVHFYQLAGMDWIDVLDALKADPRKTSELAQSLSSWPKSSP
                     GYFFDVQNRLKKFVEGGQLGIFRNGYWGHPQYKLPPEANLMGFAHYLEALDFQREIVK
                     IHAVFGGKNPHPNWIVGGMPCAINIDESGAVGAVNMERLNLVQSIITRTADFINNVMI
                     PDALAIGQFNKPWSEIGTGLSDKCVLSYGAFPDIANDFGEKSLLMPGGAVINGDFNNV
                     LPVDLVDPQQVQEFVDHAWYRYPNDQVGRHPFDGITDPWYNPGDVKGSDTNIQQLNEQ
                     ERYSWIKAPRWRGNAMEVGPLARTLIAYHKGDAATVESVDRMMSALNLPLSGIQSTLG
                     RILCRAHEAQWAAGKLQYFFDKLMTNLKNGNLATASTEKWEPATWPTECRGVGFTEAP
                     RGALGHWAAIRDGKIDLYQCVVPTTWNASPRDPKGQIGAYEAALMNTKMAIPEQPLEI
                     LRTLHSFDPCLACSTHVLGDDGSELISVQVR"
     gene            13937..14644
                     /gene="hyaC"
                     /locus_tag="RHX21_002504"
     CDS             13937..14644
                     /gene="hyaC"
                     /locus_tag="RHX21_002504"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase b-type cytochrome subunit"
                     /protein_id="HDV1987667.1"
                     /translation="MQQKSDNVVSHYVFEAPVRIWHWLTVLCMAVLMVTGYFIGKPLP
                     SVSGEATYLFYMGYIRLIHFSAGMVFTVVLLMRIYWAFVGNRYSRELFIVPVWRKSWW
                     QGVWYEIRWYLFLAKRPSADIGHNPIAQAAMFGYFLMSVFMIITGFALYSEHSQYAIF
                     APFRYVVEFFYWTGGNSMDIHSWHRLGMWLIGAFVIGHVYMALREDIMSDDTVISTMV
                     NGYRSHKFGKISNKERS"
     gene            14641..15228
                     /locus_tag="RHX21_002505"
     CDS             14641..15228
                     /locus_tag="RHX21_002505"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 1 maturation protease"
                     /protein_id="HDV1987668.1"
                     /translation="MSEQRVVVMGLGNLLWADEGFGVRVAERLYAHYHWPEYVEIVDG
                     GTQGLNLLGYVESASHLLILDAIDYGLEPGTLRTYAGERIPAYLSAKKMSLHQNSFSE
                     VLALADIRGHLPAHIALVGLQPAMLDDYGGSLSELAREQLPAAEQAALAQLAAWGIVP
                     QPANESRCLNYDCLSMENYEGVRLRQYRMTQEEQG"
     gene            15225..15623
                     /gene="hyaE"
                     /locus_tag="RHX21_002506"
     CDS             15225..15623
                     /gene="hyaE"
                     /locus_tag="RHX21_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase-1 operon protein HyaE"
                     /protein_id="HDV1987669.1"
                     /translation="MSNDTPFDALWQRMLARGWTPVSESRLDDWLTQAPDGVVLLSSD
                     PKRTPEVSDNPVMIGELLREFPDYTWQVAIADLEQSEAIGDRFGVFRFPATLVFTGGN
                     YRGVLNGIHPWAELINLMRGLVESQQERAS"
     gene            15620..16477
                     /locus_tag="RHX21_002507"
     CDS             15620..16477
                     /locus_tag="RHX21_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase expression/formation protein"
                     /protein_id="HDV1987670.1"
                     /translation="MSETFFHLLGPGTQPNDDSFSMNPLPITCQVNDEPSMAALEQCA
                     HSPQVIALLNELQHQLSERQPPLGEVLAVDLLNLNADDRHFINTLLGEGEVSVRIQQA
                     DDSESEIQEAIFCGLWRVRRRRGEKLLEDKLEAGCAPLALWQAATQNLLPTDSLLPPP
                     IDGLMNGLPLAHELLAHVRNPDAQPHSINLTQLPISEADRLFLSRLCGPGNIQIRTIG
                     YGESYINATGLRHVWHLRCTDTLKGPLLESYEICPIPEVVLAAPEDLVDSAQRLSEVC
                     QWLAEAAPT"
     gene            16611..18155
                     /gene="appC"
                     /locus_tag="RHX21_002508"
     CDS             16611..18155
                     /gene="appC"
                     /locus_tag="RHX21_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-II oxidase subunit 1"
                     /protein_id="HDV1987671.1"
                     /translation="MWDVIDLSRWQFALTALYHFLFVPLTLGLIFLLAIMETIYVVTG
                     KTIYRDMTRFWGKLFGINFALGVATGLTMEFQFGTNWSFYSNYVGDIFGAPLAMEALM
                     AFFLESTFVGLFFFGWQRLNKYQHLLVTWLVAFGSNLSALWILNANGWMQYPTGAHFD
                     IDTLRMEMTSFSELVFNPVSQVKFVHTVMAGYVTGAMFIMAISAWYLLRGRERDVALR
                     SFAIGSVFGTLAIIGTLQLGDSSAYEVAQVQPVKLAAMEGEWQTEPAPAPFHVVAWPE
                     QDQERNAFAIKIPALLGILATHSLDKPVPGLKNLMAETYPRLQRGRMAWLLMQEISQG
                     NREPHVLQAFRELEGDLGYGMLLSRYAPDMNHVTAAQYQAAMRGAIPQVAPVFWSFRI
                     MVGCGSLLLLVMLIALVQTLRGKIDQHRWVLKMALWSLPLPWIAIEAGWFMTEFGRQP
                     WAIQDILPTYSAHSALTTGQLAFSLIMIVGLYTLFLIAEVYLMQKYARLGPSAMQSEQ
                     PTQQQG"
     gene            18167..19303
                     /gene="appB"
                     /locus_tag="RHX21_002509"
     CDS             18167..19303
                     /gene="appB"
                     /locus_tag="RHX21_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HDV1987672.1"
                     /translation="MFDYETLRFIWWLLIGVILVVFMISDGFDMGIGCLLPLVARNDD
                     ERRIVINSVGAHWEGNQVWLILAGGALFAAWPRVYAAAFSGFYVAMILVLCSLFFRPL
                     AFDYRGKIADARWRKMWDAGLVIGSLVPPVVFGIAFGNLLLGVPFAFTPQLRVEYLGS
                     FWQLLTPFPLLCGLLSLGMVILQGGVWLQLKTVGVIHLRSQLATKRAALLVMLCFLLA
                     GYWLWVGIDGFVLLAQDANGPSNPLMKLVAVLPGAWMNNFVESPVLWIFPLLGFFCPL
                     LTVMAIYRGRPGWGFLMASLMQFGVIFTAGITLFPFVMPSSVSPISSLTLWDSTSSQL
                     TLSIMLVIVLIFLPIVLLYTLWSYYKMWGRMTTETLRRNENELY"
     gene            19316..19408
                     /gene="cbdX"
                     /locus_tag="RHX21_002510"
     CDS             19316..19408
                     /gene="cbdX"
                     /locus_tag="RHX21_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-II oxidase subunit CbdX"
                     /protein_id="HDV1987673.1"
                     /translation="MWYLLWFVGILLMCSLSTLVLVWLDPRLKS"
     gene            19488..20786
                     /gene="appA"
                     /locus_tag="RHX21_002511"
     CDS             19488..20786
                     /gene="appA"
                     /locus_tag="RHX21_002511"
                     /EC_number="3.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acid phosphatase/4-phytase"
                     /protein_id="HDV1987674.1"
                     /translation="MKAILIPFLSLLIPLTPQSAFAQSEPELKLESVVIVSRHGVRAP
                     TKATQLMQDVTPDAWPTWPVKLGWLTPRGGELIAYLGHYQRQRLVADGLLAKKGCPQS
                     GQVAIIADVDERTRKTGEAFAAGLAPDCAITVHTQADTSSPDPLFNPLKTGVCQLDNA
                     NVTDAILSRAGGSIADFTGHRQTAFRELERVLNFPQSNLCLKREKQDESCSLTQALPS
                     ELKVSADNVSLTGAVSLASMLTEIFLLQQAQGMPEPGWGRITDSHQWNTLLSLHNAQF
                     YLLQRTPEVARSRATPLLDLIMAALTPHPPQKQAYGVTLPTSVLFIAGHDTNLANLGG
                     ALELNWTLPGQPDNTPPGGELVFERWRRLSDNSQWIQVSLVFQTLQQMRDKTPLSLNT
                     PPGEVKLTLAGCEERNAQGMCSLAGFTQIVNEARIPACSL"
     gene            complement(20901..23081)
                     /gene="etk"
                     /locus_tag="RHX21_002512"
     CDS             complement(20901..23081)
                     /gene="etk"
                     /locus_tag="RHX21_002512"
                     /EC_number="2.7.10.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein kinase"
                     /protein_id="HDV1987675.1"
                     /translation="MTTKNMNTPPGSTQENEIDLLRLVGELWDHRKFIISVTALFTLI
                     AVAYSLLSTPIYQADTLVQVEQKQGNAILSGLSDMIPNSSPESAPEIQLLQSRMILGK
                     TIAELNLRDIVEQKYFPIVGRGWARLTKEKPGELAISWMHIPQLNGQDQQLTLTVGEN
                     GHYTLEGEEFTVNGMVGQRLEKDGVALTIADIKAKPGTQFVLSQRTELEAINALQETF
                     TVSERSKESGMLELTMTGDDPQLITRILNSIANNYLQQNIARQAAQDSQSLEFLQRQL
                     PEVRSELDQAEEKLNVYRQQRDSVDLNLEAKAVLEQIVNVDNQLNELTFREAEISQLY
                     KKDHPTYRALLEKRQTLEQERKRLNKRVSAMPSTQQEVLRLSRDVEAGRAVYLQLLNR
                     QQELSISKSSAIGNVRIIDPAVTQPQPVKPKKALNVVLGFILGLFISVGAVLARAMLR
                     RGVEAPEQLEEHGISVYATIPMSEWLDKRTRLRKKNLFSNQQRHRTKNIPFLAVDNPA
                     DSAVEAVRALRTSLHFAMMETENNILMITGATPDSGKTFVSSTLAAVIAQSDQKVLFI
                     DADLRRGYSHNLFTVSNEHGLSEYLAGKDELNKVIQHFGKGGFDVITRGQVPPNPSEL
                     LMRDRMRQLLEWANDHYDLVIVDTPPMLAVSDAAVVGRSVGTSLLVARFGLNTAKEVS
                     LSMQRLEQAGVNIKGAILNGVIKRASTAYSYGYNYYGYSYSEKE"
     gene            complement(23101..23547)
                     /gene="etp"
                     /locus_tag="RHX21_002513"
                     /gene_synonym="yccY"
     CDS             complement(23101..23547)
                     /gene="etp"
                     /locus_tag="RHX21_002513"
                     /gene_synonym="yccY"
                     /EC_number="3.1.3.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309165.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-tyrosine-phosphatase Etp"
                     /protein_id="HDV1987676.1"
                     /translation="MAQLKFNSILVVCTGNICRSPIGERLLRKRLPGVKVKSAGVHGL
                     VKHPADATAADVAANHGVSLEGHAGRKLTAEMARNYDLILAMESEHIAQVTAIAPEVR
                     GKTMLFGQWLEQKEIPDPYRKSQDAFEHVYGMLERASQEWAKRLSR"
     gene            complement(23535..24674)
                     /locus_tag="RHX21_002514"
     CDS             complement(23535..24674)
                     /locus_tag="RHX21_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide export protein"
                     /protein_id="HDV1987677.1"
                     /translation="MKKNIFKFSVLTLAVLSLTACTLVPGQNLSTSNKDVIELPDNQY
                     DLDKMVNIYPVTPGLIDQLRAKPIMSQANPELEQQIANYEYRIGIGDVLMVTVWDHPE
                     LTTPAGQYRSASDTGNWVNADGAIFYPYIGRLKVAGKTLTQVRNEITARLDSVIESPQ
                     VDVSVAAFRSQKAYVTGEVSKSGQQPITNIPLTIMDAINAAGGLTADADWRNVVLTQN
                     GVKTKVNLYALMQRGDLRQNKLLHPGDILFIPRNDDLKVFVMGEVGKQSTLKMDRSGM
                     TLAEALGNAEGMNQDVADATGIFVIRATQNKQNGKIANIYQLNAKDASAMILGTEFQL
                     EPYDIVYVTTAPLARWNRVISLLVPTISGVHDLTETSRWIQTWPN"
     gene            complement(24720..26816)
                     /locus_tag="RHX21_002515"
     CDS             complement(24720..26816)
                     /locus_tag="RHX21_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbH domain-containing protein"
                     /protein_id="HDV1987678.1"
                     /translation="MKKNSYLLSCLAIAVSSACHAEVLTYPDPLGSSQSDFGGTGLLQ
                     MPNARIAPEGEFSVNYRDNDQYRFYSTSVALFPWLEGTIRYTDVRTRKYSQWEDFSGD
                     QSYKDKSFDFKLRLWEEGYWLPQVAFGKRDIAGTGLFDGEYLVASKQAGPFDFTLGMA
                     WGYAGNAGNITNPFCRVSDKYCHRAESHDAGDISFSDIFRGPASIFGGIEYQTPWNPL
                     RLKLEYDGNNYQNDFAGKLPQASHFNVGAVYRAASWADLNLSYERGNTLMFGFTLRTN
                     FNDLRPALRDTPKPAYQPAPESEGLQYTTVANQLTALKYNAGFEAPEIQLRDKTLYMS
                     GQQYKYRDSREAVDRANRILVNNLPQGVEKISVTQKREHMAMVTTETDVASLRKQLAG
                     TAPGQSEQLQQQRVEAEDLSAFGRGYRIREDRFSYSFNPTLSQSLGGPEDFYMFQLGL
                     MSSARYWFTDHLLLDGGIFTNIYNNYDKFKSSLLPADSTLPRVRTHIRDYVRNDVYLN
                     NLQANYFADLGNGFYGQVYGGYLETMYAGVGSELLYRPLDASWALGVDVNYVKQRDWD
                     NMMRFTDYSTPTGFVTAYWNPPTLNGVLMKLSVGQYLAKDKGATIDVAKRFDSGVAVG
                     VWAAISNVSKDDYGEGGFSKGFYISIPFDLMTIGPNRNRAVVSWTPLTRDGGQMLSRK
                     YQLYPMTAEREVPVGQ"
     gene            complement(26816..27562)
                     /locus_tag="RHX21_002516"
     CDS             complement(26816..27562)
                     /locus_tag="RHX21_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule biosynthesis GfcC family protein"
                     /protein_id="HDV1987679.1"
                     /translation="MNKLQSYFIASVLYVMTPHAFAQGTVTIYLPGEQQTLSVGPVEN
                     VVQLVTQPQLRDRLWWPGALLTDSAAKAKALKDYQHVMAQLASWEAEADDDVAATIKS
                     VRQQLLNLNITGRLPVKLDPDFVRVDENSNPPLVGDYTLYTVQRPVTITLLGAVSGAG
                     QLPWQAGRSVTDYLQDHPRLAGADKNNVMVITPEGETVVAPVALWNKRHVEPPPGSQL
                     WLGFSAHVLPEKYADLNDQIVSVLTQRVPD"
     gene            complement(27559..28203)
                     /gene="gfcB"
                     /locus_tag="RHX21_002517"
     CDS             complement(27559..28203)
                     /gene="gfcB"
                     /locus_tag="RHX21_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein GfcB"
                     /protein_id="HDV1987680.1"
                     /translation="MRPLILSIFALFLAGCTHSQQSMVDTFRASLFDNQDITVADQQI
                     QALPYSTMYLRLNEGQRIFVVLGYIEQEQSKWLSQDNAMLVTHNGRLLKTVKLNNNLL
                     EVTNSGQDPLRNALAIKDGSRWTRDILWSEDNHFRSATLSSTFSFAGLETLNIAGRNV
                     LCNVWQEEVTSTRPEKQWQNTFWVDSATGQVRQSRQMLGAGVIPVEMTFLKPAP"
     gene            complement(28310..28615)
                     /locus_tag="RHX21_002518"
     CDS             complement(28310..28615)
                     /locus_tag="RHX21_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415507.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine-rich inner membrane protein GfcA"
                     /protein_id="HDV1987681.1"
                     /translation="MKHKLSAILMAFMLTTPAAFAAPEATNGTEATTGTTGTTTTTTG
                     ATTTATTTGGVAAGAVGTATVVGVATAVGVATLAVVAANDSGDGGSHNTSTTTSTTR"
BASE COUNT         6950 a         7362 c         7627 g         6893 t
ORIGIN      
        1 ggaattttat gaaaagcctc tcctataagc ggatctataa atcacaagaa tacctggcaa
       61 cgttgggcac aattgaatac cgatcattgt ttggcagtta cagcctgacc gttgacgaca
      121 cggtgtttgc gatggtttct gatggtgagt tgtatcttcg ggcttgtgag caaagtgcac
      181 agtactgtgt aaaacatccg cctgtctggc tgacatataa aaagtgtggc cgatccgtta
      241 ccctcaatta ctatcgggtt gatgaaagtc tatggcgaaa tcaactgaag ctggtgcgtc
      301 tgtcgaaata ttctctcgat gcagcgctga aagagaaaag cacgcgcaat acccgggaaa
      361 gactgaaaga tttgcccaat atgtcttttc atctggaagc gattctcggg gaggtgggga
      421 ttaaggatgt acgggcgtta cgtatacttg gggcaaaaat gtgttggttg cgactgcggc
      481 agcaaaacag tctggtgaca gaaaagattc tgtttatgct tgaaggtgcc attatcggca
      541 ttcatgaagc tgcgctcccg gtggcacgcc gccaggagct tgcagaatgg gctgactctc
      601 ttacgccgaa acaggagttt cctgcggaac ttgagtaatc tggcgttgca gacgaccaat
      661 ctcaggcagt aatgcaatca ataatccaac ttgttgtacg accagaggtt ctttgctgtc
      721 tgcccgtggt tcaagttgct gcatccgctg tttcaggcta gctaatgcct cattgacgcg
      781 ttcttcatca gcaggttgat gatgtaacgc gtcatcaaca tagcaaactg cgtcatcaag
      841 aaacgccaga atttcaggat tagttaactg ctcccggtga gcaccgaggg ctgagatata
      901 gctggtaaac gtatggttaa ggcacagcaa ccgaaacgcg gcttcgcgaa tttgcggggt
      961 aacgttcggc tcgctggaca tatttgatac caccgacgcc agctcagcat cacggttgtg
     1021 tgcatcgcgg cgggcaatac gatacgccag acggttatca cgcccctgat ggtattgctc
     1081 cagtatggca tcgagatacc gacagttggc ctctgtggcg cgttcgagca tgcgcggcag
     1141 attgcgaaac tgccagtcag gccagatgta gctcactgcc gcccacgcaa tggcacaacc
     1201 aatcagcgta tcgattacgc gaggtaacgc tacttcaaaa ccttcaccca gtaagttaaa
     1261 acacagtagc accaaaagtg tgatgaacat cgttgcatga gcgtattgca cgttacggaa
     1321 ggcaaaaaag agcacgccgg taataaccag cagcaccagc tgcccttcca gtgatggcac
     1381 aaaccacagc acaggaatgc caatggcgat acctaccagc gtaccaataa tccttaactt
     1441 caggcggtgg cgcgtggcgt tatagtttgg ctggcagaca aacaaacttg tcagcaagat
     1501 ccaatacccg tgatgcattc cggttatttg aatgatggcg tagccgaagc acaacaccag
     1561 cgacattctt accgcatgac ggaagagggc ggattccggc gtgaagtgac ggctaagacg
     1621 cagccagata tcactcaacc cgtgcgggct gtcatcagcg agctcatttt cgtcattatt
     1681 atggggtagt gcctgggcct gttctgattc aattgttgcc agttgggcat caatggcgcg
     1741 taaattgttc agcaaaaatc ccagtgtttt gagtaaatcg gcgggtgcgc cgttatcgcg
     1801 catccgctcc agcgcagcat caatatgcgt aaaagcgcgc tcaaaatgcg gatcatgttg
     1861 ataaggctga cgcagcaaaa tacagcgtga cagttgctgg cacgcctggc cctgcatcga
     1921 catcagccgc tgaaaacgga acagcacgtc gctgtggcga aaatgttcac gcaatgtttg
     1981 atactgaata tgagaagagc tggcacgctc gtgaatatcc tgcgcgacaa agtaataatg
     2041 cagcgtgcga cgcgttcccc gttgaccacg atcgccacgt aagcgggtca gcagcgagag
     2101 tttcgtctga ttcaatgtcg ccatcagttg tccgttggcg agagccaaat cgtacagcgg
     2161 tgcctggctt tcatcttcaa tatcaggatc aaacatgcgc gacttgagct caagataacg
     2221 cgccagttgt tcatagcaac gcgccaggtt gtcctgcagc gggcggaccg ggaacagcag
     2281 atgaccaata agtgtcagga cgttgtacca gacggcaccg gccagcagat acatcggctg
     2341 ctgataccag tgctcataca gtgatgttcc caacatagtg taaatggcga tcagcaatgc
     2401 accgaaggca attgttgcat agcgttgacc cagaccgccg agcaaaatga agccgctggt
     2461 agagagcgtt aagccaatcg caaatagcca gggccaggga aacagcaatt ctactgaggc
     2521 cgaggcgata aaaaagcaga acagcgtaat gatgaggtta cgcaaacgtc ccgccagtcg
     2581 gtcatcgaga tcggtcagcg ccgctgccac catccccagc gttagcggaa tcgtcagttt
     2641 tacatcaccc agccaccacg gaaacgctgt ggttccacaa agcgcaataa aaatacgcgc
     2701 gtaatacagc caggcgctgt tccaggtata gcgtttgagc aaaggactta gcataaaggc
     2761 catattagtg gattattcaa aacgacgacg tgcattggct tcacgcgcag cttgcgctgt
     2821 ttctaccgat accacgcgac gaccaaccgg ccatagtgca atagcggcaa ttttaaagtt
     2881 cgcaatgccg acaggaatgc caatgattga aatacattgt gcgatgcccg ttgcaatgtg
     2941 catcaggcat aaccaccagc caaagaaaat cagccagaaa atattcaata ccgtaccgcc
     3001 agtattcagc agcacatttt tgccagccgg gttcagttca tcgacatgaa tagcttcatt
     3061 gccataaggc accagagaca gtttagtgat ctcccagcag gatcgtgtca gcggtaaggt
     3121 aaaaatcagc acaatactga ccagagtcgc caacagccag cccagagtgg tggcaaatcc
     3181 gccaagcaca aagttcagaa tgttcaaaac ggtacgcata aaacctcgct ttactgtggt
     3241 tttcagtaat gggcggcaat tgtaacgttt ttttgggctg gagcacgttt tctctgacgg
     3301 ttacactgat aagaaataat ttcgtgtgga tctacagagt catggaactg aaagcgacaa
     3361 cgcttggaaa acgtctggca cagcaccctt acgatcgggc ggtgatcctc aatgccggga
     3421 ttaaagtctc cggcgatcgc cacgaatacc ttattccttt caatcaatta ctggcgattc
     3481 actgtaagcg cggtctggta tggggcgagc tggaatttgt actgccggac gaaaaagtgg
     3541 tgcgtctgca cggcaccgaa tggggcgaga cgcagcgttt ttaccatcat cttgatgctc
     3601 actggcggcg gtggagtggc gagatgagcg aaattgcgtc tggtgtttta cgccagcaac
     3661 tggatttgat tgccacgcgc actggagaaa ataaatggct gacgcgtgag caaacctctg
     3721 gcgttcagca acaaatccgc caggctatgt cggcgttgcc gttgccggtt aaccgactgg
     3781 aagaattcga taactgccgt gaggcgtggc gtaaatgtca ggcctggttg aaagatattg
     3841 aaagcgctcg gttgcagcat aaccaggcgt ataccgaagc catgcttacc gagtatgcgg
     3901 attttttccg ccaggtcgag tcttcaccgc tgaatccggc gcaggcccgg gcagtcgtta
     3961 atggcgagca ttctctgtta gtgctggcag gtgcaggaag cggaaaaacg tcggtgctgg
     4021 tggcccgtgc aggctggttg ctggcgcgtg gtgaagcgtc ccctgagcaa attttattgc
     4081 tggcgtttgg tcgcaaagcc gctgaagaga tggacgagcg tattcgcgaa cggctacata
     4141 ccgaagacat taccgcacgc acgtttcatg cgctggcgct gcatattatt cagcagggca
     4201 gcaaaaaagt tccgatagtc agcaaactgg aaaatgatac cgctgcccgt catgaactct
     4261 ttattgctga gtggcgcaag caatgcagcg aaaagaaagc gcaggcgaag ggctggcggc
     4321 aatggctgac ggaagaaatg cagtggtcag tgccagaagg taacttctgg gatgatgaaa
     4381 aattacagcg tcgtcttgcc tcacgcctcg atcgttgggt aagtctgatg cggatgcacg
     4441 gtggtgcaca ggcagaaatg attgccagtg cacccgaaga gattcgcgat ctgttcagta
     4501 aacgtatcaa gttgatggcc ccgttattaa aagcctggaa aggtgcgctg aaggcagaaa
     4561 acgctgtcga tttttcgggc cttattcatc aggcgattgt gattctggag aaaggtcgct
     4621 ttatcagccc gtggaagcat attctggttg atgaatttca ggatatctcg ccgcagcggg
     4681 cagcgttgtt agcggcatta cgcaagcaaa acagtcagac gacgttgttc gccgttggtg
     4741 atgactggca ggcgatttac cgattcagcg gtgcgcaaat gtcgctcacc accgctttcc
     4801 atgaaaactt tggtgaaggc gatcgctgtg atttagacac gacttaccgt tttaacagtc
     4861 gtatcggtga ggtggcaaac cggtttattc agcagaaccc aggccagttg aaaaagccgc
     4921 taaacagctt aaccaatgga gacgaaaaag ccgtcacgtt attggatgag agtcaacttg
     4981 acgctttgct ggataagctc tctggttatg ccaaaccgga agagcgcatt cttatcctgg
     5041 cgcgttacca tcacatgagg cctgccagcc tggaaaaagc ggcaacacgc tggccgaagt
     5101 tgcaaatcga ctttatgacc attcatgcca gcaaagggca acaggcggat tacgtcatca
     5161 tcgttggctt gcaggaggga agtgatggtt ttccggctgc ggcgcgggag tcgattatgg
     5221 aagaggcgct actgccaccg gttgaggatt tcccggacgc tgaagaacgg cggttaatgt
     5281 acgtggcgct gacccgggca cgccatcggg tatgggcact gtttaacaaa gagaatccct
     5341 ctccctttgt ggaaatactg aaaaatctgg atgtgccggt ggcgagaaaa ccgtaagaaa
     5401 caggtggcgt ttgccacctg tgcaatatta cttcagacgg tccgcgagat aacgctgata
     5461 atcggggatc agaatatcga ccgcgtcgtt gaaatgcggc gactggatta tgaagtctgc
     5521 cgttgccacg ttggtggcga ctggaatgtt ccataccgtc gccagacgca gcaaggcttt
     5581 cacgtcagga tcgtgcggca cggcatttag tggatcccag aagaaaatca atacatcaat
     5641 tttcccttct gagatcaatg cgccaacctg ctggtcaccc cccattgggc cactcaacat
     5701 cgcgttgacg ttcatgccgg tcgcgcggga aattaagtta ccggtagtgc ctgttgcata
     5761 cagtacgtgt tgttccagta acggttgatg ccgttccacc cagctcatca gcatttgttt
     5821 gcagtgatcg tgtgccacca gcgcaatatg tttccgcgca ggtaaagtgc gagtcgtcag
     5881 ttccataatg tacatccgta gttaactttc ctacagatta ctgtaagcac ttatcgctgc
     5941 aagataaaga ccgaaaaagc ctgcgcacag gcacaaaaat ctcaggaaga tggttgtttt
     6001 tccgcccact gcaggaaagt atttcgcgtt tgtgggtcag ccagtttaaa ccaatacttc
     6061 agccgttgtt ctgtgagcac ctgagactgc ggtggaatag catccagctc ggaaacaccc
     6121 gagagcagcg tactgtcatc tgccatcatc gtggcaaatt gcggtagtga agcgcgtttc
     6181 gcggatttgt tatagcgttc aacctcgacc tcataatcaa tcgtttttgc cgttgaggta
     6241 atggcgagaa tatccagctt taccggaatc ggcgtcgcat cgccatccaa caattcaagg
     6301 cgcggcgcgg catcaaaatg gttagcttcc cgctcattct ccaggcgagg caggcgaaaa
     6361 ttgacctggt tgatgagctg ggtattaaaa ctgaccacca gcggtgggga gatatacagc
     6421 cgttcttcac tattggaaag atgaatcgtc ttctcaacgc gaaacactaa ctgatgcggt
     6481 ccattatcca gttcaatgct gtccgcaccg cgcagcagag agctggaaac cttcttgccg
     6541 tcgagtacca gaagatcgac atcggttgaa agccgcagcg tggtggcaaa aacggatacc
     6601 ggcaaacata atgcaatcaa ggtggtcacg atgccggttt tcataggtag ctcctgtcaa
     6661 aagaccgccc gaataataat gtgtcaaaat ttttctttaa tcatacttac taacatatag
     6721 acatatttcc cgcttttgct ctcattcatt cgtattagct gcatggttgg catgtcggct
     6781 ttgtcgtaca ctttgttaaa cagtctggag gaaataatga aagaaaccga tattgcaggc
     6841 attttaacgt ccactcacac cattgcgctg gtgggggcaa gcgacaaacc cgatcgtccc
     6901 agctatcgcg tgatgaaata tctactcgac caggggtatc acgtcattcc ggtttcgcca
     6961 aaagttgccg gcaaaacgct gctgggccag caggggtatg gcacgctggc agacgttccg
     7021 gaaaaggtcg atatggtcga tgttttccgt aattcagaag cggcgtgggg cgtggcacag
     7081 gaagctattg ccattggcgc gaaaaccctc tggatgcaac tgggggtgat taatgagcaa
     7141 gcggcagtac tggcacggga tgccgggtta aatgtggtga tggatcgctg cccggctatt
     7201 gagatccctc gcctgggcct ggccaaataa aaaatccccg gaaggcaaaa accttccggg
     7261 gattcgttca gggattagtt acgcagacgc ggggcctgga gttgtttgcg gatggtctgc
     7321 gccagctcat ccatggatgg ctgttcagga tgttcatcct gcaattcgct acttagctgg
     7381 gcttcagcca ggtaggtatg aaccggtagg ccgttatcgt cctccatcac cacgtgatac
     7441 cacggagcgg cgcgaagctc gtcattcacc gccagctcat caggcgacgg ttcagagagc
     7501 gaataaaccg ggtcgatatc cacgaccact ccgagataac ctaacaggga atggcggacc
     7561 tgctggccga taccgaattt gctggcaatc atagtcacct cccgggaaat ctttaccttt
     7621 gatataaggg taaaattcca catttcaagt tacatgacgc gacaggcaaa ccctttcaga
     7681 tatagccctt ccgggtaggt agcgatcacc ggatgatcgg ctgcctgacg gaactgctct
     7741 ataaattgta catcacggcc ggcatcaatt gcggcatccg cgatgatttt ctgaaataaa
     7801 tcgctggtca tcagaccgga acaggagaaa gtcaggagaa taccgccttc attcagcaac
     7861 tgaatcgcca gcatgttgat atctttatag ccacgacacg cgcccatcaa ctggctttta
     7921 ttctcaacaa acttcggcgg gtccatcacg ataacgtcaa atttttcacc gcgatcgcga
     7981 taagtacgca gcaatttaaa gacatcatca cggacaaact cagccttgct cagatccagt
     8041 ttgttcagct caacgttctg ccgtgcaata tccagcgctt cctgggaggt atcaacgctg
     8101 acaacctggc tgcaaccgcc catcagtgcc gatacggcga aaccaccggt ataggagaaa
     8161 cagttcagca cacgtttatt ttcaacgtag cggcgggtag ccaggcggct atcacgctgg
     8221 tccaggtagt agcccgtttt gtgtccgtgc tgaatatcca ccagcagttt catgccgtgt
     8281 tcttcaatcg gcagcagggc aggtggcaac tcgccggtga cgaggccctg ggtcagctcc
     8341 atcccttctt ttttacgtac cgcaacatcg ctgcgatcgt aaatcgcaca ttccgggtac
     8401 agcgtttgca gggcactaat taatgccgcg cgctgatatt ctgcgccagc actcagcagt
     8461 tgcagcacca gaaaattacc gaaacgatcg atagtaatac ccggcaggcc atcagattct
     8521 ccggcgatta aacgatagct gtcgaggcca tctttttgcg ccagccagtc acgccatttt
     8581 tgtgcttgtt gcaaacggcg ggaaaaaaaa gcaatgtcga tagactcaga cgggtcaaac
     8641 gtccagacgc gcgcccggat ttgcgaagct ggtgaataag cgccgcgtgc taaccatttt
     8701 ccctgatgat caacaatatc gatggtttca ccgaggctgg ctttaccttc catgcgggca
     8761 acggccccgg aaaagaccca cggatggcga cgaagtaatg atttttcgcg ccctttggct
     8821 aacactaaac gtacactcat aatttacttt tctgtcgatg caaagaaatg ggcgtcattg
     8881 tccggagttt tccatggatt tgcaacgcgt ccattaagga taaggagagc agcaatgtcg
     8941 aaagtctgca taattgcctg ggtttacggg cgagttcagg gcgtaggatt tcgctacacc
     9001 acacagtatg aagcgaaaag actgggttta accgggtacg ccaaaaatct tgacgatggc
     9061 agcgtggaag tggttgcctg cggtgaagaa gggcaggtgg aaaaattaat gcagtggtta
     9121 aagagtggcg gcccgcgttc tgcgcgtgtg gaacgggtgc ttagcgagcc gcatcatccc
     9181 tcgggggaat tagccgattt tcgtatccgt taaatacatt ttaccggttt tggcaggcca
     9241 gcaattttgg tggcttgctt agccggacct ttcggaaaca gtcgatataa atagcggctg
     9301 ttaccttttt cttcgccaaa tttattcgcc atcgctttta ccagcatacg aatcgccgga
     9361 gaagtattga attccagata gaaatcacgc acaaaacgca ccacttccca gtgttctggc
     9421 gacagcgaaa tcccttcgtt ctctgcaatc accacagcca gcggctcact ccactggctg
     9481 ctttctttga gatagccttc ggtatccgtt tctatctctt taccttcgaa gatcagcata
     9541 attattacta ccttaatcag actggcggca gtgtaacaaa aaacaaagcc ccgcataaag
     9601 cgaggctatg aaagtgttag cgggtgagat taatcgcggc tagcgaagcc cagaatgctc
     9661 agcaggctga cgaagatgtt gtacagcgaa acatacaggc taaccgtggc acgaatatag
     9721 ttcgtctcac cgccatgaat gatgttgctg gtttcaaaca agatagcgcc agaggagatc
     9781 agaatgaaga ccgcgctgat cgccagatgc agagcaggca gttgcaggaa gatattagca
     9841 accataccaa tcagcaccac cacaataccc gccatcagca taccgccgag gaacgacata
     9901 tctttgcggg tggtcagcac atatgcagag cagcagaaga acactaacgc cgttccgccc
     9961 agtgccatag cgattacgtc acccattccg gcagacagat aggtgttcag aataggtccg
    10021 aggatataac ccagaaaacc ggtaaaggcg aatgcggaga taatcccggt cggcttattc
    10081 gccgttttat aggtcaggaa catcaaacca tacataccca ccagcgtcag aatcagaccc
    10141 ggagatggca gcatcagcac cgtactggca gttgcggtaa tcgccgaaaa ggccagcgtc
    10201 aggctcagca gaaaataggt attacgcagc accttatggg tgctaagcag tgatgtacgg
    10261 tcatgtgaag aactaacaat acgatccatt gagtcactct ctatgacaga tgtaattaat
    10321 taagcagcat aatgataatg cgtaagggca cccagaagtt ttacccatct ttacgcattt
    10381 gatctggaac aggtttaaca gcggattatc aggtcattaa gcaaatataa cgccctgaga
    10441 atttcgacag gcaaaagaaa aaggggttag catttagcta accccttatc ttatttggcg
    10501 gaagcgcaga gattcgaact ctggaaccct ttcgggtcgc cggttttcaa gaccggtgcc
    10561 ttcaaccgct cggccacact tccggaatga cgcgcactat aaacatcccg atgcggcgtg
    10621 taaaccccta atttgtttgt ttgcctgaaa aacagccaaa agtgcattga tagcgtgaaa
    10681 taacagcaga ttgatcattt catcaccatg aattccttct cttttactcg tttagcaacc
    10741 ggctaaacat ccccaccgcc cggccaaaag aaaaataggt ccatttttat cgctaaaaga
    10801 taaatccaca cagtttgtat tgttttgtgc aaaagtttca ctacgcttta ttaacaatac
    10861 tttctggcga cgtgtgccag tgcagaagga tgagctttcg ttttcagcat ctcacgtgaa
    10921 gcgatggttt gccttgctac agggacgtcg cttgccgacc ataagcgccc ggtgtcctgc
    10981 cggtgtcgca aggagaagag acgtgcgata tgaataacga ggaaacattt taccaggcca
    11041 tgcggcgtca gggcgttacc cggcgcagct ttctcaaata ttgtagtctg gctgccacgt
    11101 cgctgggatt aggcgcggga atggcaccaa agattgcctg ggcgctggag aacaaacccc
    11161 gcattccggt ggtatggatc cacggtctgg aatgcacctg ctgtaccgaa tcttttatcc
    11221 gctccgctca cccactggcg aaggacgtca tcctttccct gatttccctc gattatgacg
    11281 atactttgat ggctgccgcc ggaacccagg cggaagaagt cttcgaagac atcatcacgc
    11341 aatacaatgg caaatatatc ctcgcagtag aaggtaatcc gccgctgggc gagcagggga
    11401 tgttctgtat cagcagcggt cgaccgttta ttgagaaact caaacgtgcc gctgccggag
    11461 ccagcgcgat tatcgcctgg ggaacctgcg cgtcctgggg ctgcgtgcag gccgcgcggc
    11521 ccaatccgac gcaggcaacg cctatcgaca aagtcatcac cgacaaaccc attatcaaag
    11581 tacctggctg cccgccgatc ccggatgtga tgagcgccat cattacttac atggtgacct
    11641 ttgatcgctt gccagatgtc gacagaatgg gccgtccgct gatgttctat ggtcagcgaa
    11701 tccacgataa atgctatcgc cgcgcccact tcgacgccgg agagttcgtc cagagttggg
    11761 atgatgacgc tgcccgcaaa ggttactgcc tgtacaaaat gggctgcaaa gggcctacca
    11821 cctataacgc ctgttcctcc acacgctgga atgatggcgt ttctttccca atccagtctg
    11881 gtcacggctg cctgggctgt gcggaaaatg gtttctggga tcgcggttcg ttctacagcc
    11941 gcgtggtcga tattccgcaa atgggtactc attccaccgc cgataccgtc ggtttaaccg
    12001 cgcttggcgt ggtggcagcg gctgttggtg tgcacgcagt cgccagcgcc gttgaccagc
    12061 gcagacgtca taaccagcaa cctacagaaa ccgaacatca gccaggcaat gaggataaac
    12121 aggcatgagc actcagtacg aaactcaggg atacaccatc aataatgccg gacgccgcct
    12181 ggtggtcgac ccgattacgc gcatcgaagg ccacatgcgc tgcgaagtga atattaacga
    12241 tcagaatgtg atcaccaatg ccgtctcctg cggcaccatg tttcgcgggc tggagatcat
    12301 tctgcaaggg cgcgacccgc gcgatgcgtg ggcgttcgtt gaacgtatct gcggcgtctg
    12361 tactggcgta cacgccctgg cttcggttta cgccatcgaa gatgctatcg gtattaaagt
    12421 gccggacaac gccaatatca tccgcaacat tatgctggca acgctctggt gccacgatca
    12481 tctggtgcac ttctatcagc ttgccgggat ggactggatc gatgtgttag atgcgctgaa
    12541 agccgacccg cggaaaacct ccgaactggc gcaaagtctc tcctcttggc cgaaatcatc
    12601 ccctggctat ttcttcgacg tacaaaaccg cctgaaaaaa tttgttgaag gcgggcagtt
    12661 ggggatcttc cgcaatggct actgggggca cccgcagtac aaactgccgc cagaagctaa
    12721 cctgatgggc tttgcccact atctcgaagc tctcgatttc cagcgtgaaa ttgtgaaaat
    12781 ccacgcggtc tttggcggta aaaacccgca tccaaactgg attgtcggcg ggatgccttg
    12841 cgccattaac attgacgaaa gcggcgcggt cggggcggtc aatatggaac gcctgaacct
    12901 ggtgcagtcg attatcaccc gcacggcaga cttcattaac aacgtgatga tccccgacgc
    12961 cttagccatc ggtcagttca acaaaccgtg gagcgaaatc ggcacgggtc tttctgataa
    13021 atgtgtcctc agctacggcg cattcccgga tattgccaac gactttggtg agaaaagtct
    13081 gctgatgcct ggcggcgcgg tgattaacgg cgacttcaac aatgtgctgc cagtggattt
    13141 ggttgatccg cagcaggtgc aggagtttgt cgatcacgcc tggtatcgtt atcccaacga
    13201 tcaggtcggg cgtcatccat tcgatggcat taccgacccg tggtacaacc ccggcgatgt
    13261 caaaggcagc gataccaaca ttcagcagct gaatgaacag gaacgctact cgtggatcaa
    13321 agcgccacgc tggcgcggta acgcgatgga agtggggccg ctggcacgca cgttaatcgc
    13381 ttatcacaaa ggcgatgctg cgaccgttga gtcggtcgat cgcatgatgt cggcgttgaa
    13441 cctgccgctt tccggtatcc agtcaacgtt aggccgcatt ttgtgccgcg cgcacgaagc
    13501 gcagtgggcc gcaggtaagt tgcagtattt cttcgacaag ctgatgacca acctgaaaaa
    13561 cggcaatctc gccactgctt ccacggaaaa atgggaacct gcaacctggc cgacagagtg
    13621 ccgtggtgtc ggttttaccg aagcgccgcg cggggcgtta ggccactggg ccgccattcg
    13681 cgatggcaag attgatctct accagtgcgt ggtgccgacc acctggaacg ccagcccgcg
    13741 cgatcccaaa gggcagattg gcgcttatga agcggcgctg atgaacacca aaatggcgat
    13801 ccccgagcaa ccgctggaga tcctgcgtac tctgcacagc tttgacccgt gcctcgcctg
    13861 ttcaacacac gtgctgggcg acgacggtag cgagctgatc tccgtgcagg tgcgttaaca
    13921 gcgaaggaga atcatcatgc aacagaaaag cgacaacgtt gtcagccact atgtctttga
    13981 agcgccagtc cgcatctggc actggttgac ggtgttatgc atggcggtgt tgatggtcac
    14041 cggatacttt atcggcaagc cgctaccttc cgtcagcggc gaggcgacgt atctgttcta
    14101 tatgggctac atcaggttaa ttcacttcag cgccgggatg gtttttaccg tggttttgct
    14161 gatgcggatc tactgggctt ttgttggcaa tcgatactcc cgcgagctgt ttatcgtgcc
    14221 ggtatggcgt aaaagctggt ggcagggcgt gtggtatgaa atccgctggt atctgtttct
    14281 ggcaaaacgt ccgagtgccg atataggcca taatcccatc gcccaggcgg cgatgttcgg
    14341 ctatttcctg atgtcggtct ttatgatcat cactggtttt gcgctgtaca gcgaacacag
    14401 ccagtacgct atttttgcgc cgttccgtta tgtggtggaa tttttctact ggacgggtgg
    14461 caactcaatg gacattcaca gctggcatcg gctggggatg tggctgattg gcgcgtttgt
    14521 gatcggtcat gtctacatgg cactgcgtga agacatcatg tccgacgaca cggtgatctc
    14581 caccatggtc aacggctacc gtagccacaa atttggcaaa ataagtaaca aggagcgttc
    14641 atgagcgagc aacgcgtggt ggtcatgggg ctgggcaacc tgctgtgggc cgatgaaggc
    14701 ttcggcgtgc gggtggcgga acggctgtat gcccattacc actggcccga gtatgtggag
    14761 attgtcgatg gcggtactca gggactgaac ttgctggggt atgtcgaaag cgccagccat
    14821 ctgttgattc tcgatgccat tgactacggg ctggaacctg gaacgctgcg aacctatgcc
    14881 ggagaacgca ttccggctta tctcagcgcg aagaaaatga gcctgcatca gaacagtttc
    14941 tccgaagtgt tggcgctggc ggatatccgc ggacatctgc cagcacatat tgccctcgtc
    15001 ggtctgcaac ccgcaatgct cgacgactac ggcggtagcc tgagcgaact ggcacgggag
    15061 caactgcccg ctgcggaaca ggcggcgctg gcgcagctgg ctgcgtgggg aattgtgccg
    15121 caaccggcta atgaatcgcg ctgtctcaat tatgactgtc tgtcgatgga aaattacgaa
    15181 ggcgttcgct tgcgccagta ccggatgaca caggaggagc agggatgagc aacgacacgc
    15241 catttgatgc gttgtggcaa cgaatgctgg cgcgcggctg gacgccagtc agtgaatccc
    15301 gtcttgacga ctggcttacg caagcgccag acggcgtggt gttattaagc agtgacccga
    15361 aacgcacgcc agaggtcagc gataatccgg taatgattgg cgaattactg cgcgagtttc
    15421 ccgactatac atggcaggtg gcgattgctg accttgagca gagcgaagcc atcggcgatc
    15481 gctttggcgt ctttcgcttt cctgccactt tagtgtttac cggcggaaac tatcgcggcg
    15541 tgctgaatgg tattcacccg tgggcggaac tgataaacct gatgcgcggg cttgtcgaat
    15601 cgcagcagga gcgtgcctca tgagcgaaac ttttttccat ctgctggggc caggaacgca
    15661 accgaacgat gacagtttca gcatgaatcc actgccgatc acctgtcagg tgaatgatga
    15721 accgagtatg gcggccctgg agcaatgtgc tcacagcccg caggtgattg cgctgttaaa
    15781 cgagttacaa catcaactaa gcgaacgcca accgccgttg ggcgaggtgc tggcagtcga
    15841 tctgttaaat ctcaacgccg acgatcgtca ctttatcaat acgcttctcg gggaagggga
    15901 agtgtcagtg cgcattcagc aggctgacga cagtgaaagt gaaatacagg aggcgatctt
    15961 ctgcggatta tggcgggtgc gcagacgtcg cggcgaaaag ttgctggagg acaaactgga
    16021 ggctggctgc gcgccgctgg cgttgtggca ggcggcaacg caaaatctct tgccgacaga
    16081 ttcgctgtta ccgccgccca ttgatggcct gatgaatggc ctaccgttgg cgcatgagtt
    16141 actggcacat gtacgtaacc ccgacgcgca gccgcacagc attaatctga cgcaattacc
    16201 catcagcgag gctgatcggc tttttctctc acgtctctgt gggccgggaa atattcagat
    16261 tcgtaccatt ggctatggcg agagctatat caacgccacg gggttacgcc atgtctggca
    16321 tttacgctgt acggacacct taaaaggccc gttactggaa agttatgaaa tctgcccaat
    16381 accggaagtg gtgctggcag cgccagaaga tttggtcgac tctgcgcagc ggcttagcga
    16441 ggtatgtcag tggctggcgg aagctgcacc gacgtaaaaa gacggtaagt atcgctttca
    16501 gtcttatgaa tatcgcaatc ggcgaatacc tctggtcgta gagtttcagg ataaagaggg
    16561 agatctacca ttatcgggtt atttttctct cttcgcctac aggagtgcgc atgtgggatg
    16621 tcattgattt atcgcgctgg cagtttgctc tgaccgcgct gtatcacttt ttatttgtac
    16681 cccttaccct ggggctgatt tttttgctgg ctatcatgga aaccatttac gtggtcaccg
    16741 gcaaaacaat ctaccgcgat atgacgcgct tctggggtaa gctcttcggt atcaattttg
    16801 ctcttggcgt ggctaccggc ctgaccatgg agtttcagtt tggtactaac tggtcattct
    16861 attccaacta tgtgggcgat atttttggcg caccactggc gatggaagca ttaatggcct
    16921 tcttcctcga atccaccttt gtcgggctgt tcttcttcgg ctggcagcgg ctgaataaat
    16981 accagcacct gctggtgacg tggctggtgg cgttcggttc aaatctctct gcattgtgga
    17041 tattgaatgc caacggttgg atgcaatacc cgaccggtgc gcattttgat atcgacaccc
    17101 tgcgtatgga gatgaccagc ttcagcgagc tggtctttaa cccggtcagc caggtgaaat
    17161 ttgtgcacac cgtaatggcg ggctacgtga ccggggccat gtttattatg gcgatcagcg
    17221 cctggtattt actgcgcgga cgggagcgcg atgtcgcatt acgttcgttt gccatcggtt
    17281 ccgtcttcgg tactctggcg attatcggta ccctgcaact cggagacagt tctgcgtatg
    17341 aagtcgcgca agtacaaccg gtaaaactgg cggcgatgga aggggagtgg caaacggaac
    17401 ctgcacctgc accgttccat gtggttgcct ggccggaaca ggatcaagag cgtaacgcct
    17461 ttgccatcaa aattcccgcg ctgctaggga tcctcgccac tcactcatta gataaacccg
    17521 tgccgggtct gaagaatttg atggctgaaa cctacccacg cttgcaacgc ggacgtatgg
    17581 cctggctgtt aatgcaggaa atatcgcaag gcaatcgtga gccgcatgtg ttgcaggcat
    17641 tccgggaact ggaaggtgac ctgggctacg gcatgttgct ctcccgctat gcgccggata
    17701 tgaatcatgt cacagccgca cagtaccagg cggcgatgcg tggcgcgata cctcaggttg
    17761 cgccggtatt ctggagtttc cgcatcatgg tgggctgtgg ttccctgctg ctactggtga
    17821 tgctgattgc gcttgtccag acgctgcgtg gcaaaatcga ccagcatcgc tgggtgctga
    17881 aaatggcgct ctggagtttg ccgttgccgt ggattgcgat tgaagccggg tggtttatga
    17941 ccgagtttgg tcgtcagccg tgggcgatac aggacatctt accgacatac tccgcgcact
    18001 ccgctttaac cacaggacaa ctggctttct cactgatcat gatcgtaggg ctttacaccc
    18061 tgttcttaat cgccgaagtc tacctgatgc agaaatatgc ccgtctgggg ccgagcgcga
    18121 tgcagagtga acaaccgacg cagcaacagg ggtaaaggag aaaatcatgt ttgattatga
    18181 aacattgcgc ttcatctggt ggctgctgat tggcgtgatc ctggtggtct ttatgatctc
    18241 cgacggattt gacatgggga tcggctgtct gctgccgctg gtggcgcgta atgatgatga
    18301 acgccggata gtgataaaca gcgttggtgc acactgggaa ggcaaccagg tctggttgat
    18361 cctcgctggt ggggcattat ttgccgcctg gcccagagtg tatgcagcgg cgttttccgg
    18421 cttttatgtg gcgatgatcc tggtgctgtg ctcactgttc ttccgcccgc tggcctttga
    18481 ttatcgcgga aaaatcgccg atgcacgctg gcgtaaaatg tgggacgccg gtctggtcat
    18541 cggcagtctg gtgccgccgg tagtcttcgg tatcgccttc ggcaacttgt tgctcggcgt
    18601 gccgtttgcc ttcacaccgc aattacgcgt ggagtatctt ggcagcttct ggcaactgct
    18661 gacgccattc cctttattgt gcggattgct cagccttggg atggtgattt tgcaaggtgg
    18721 cgtctggtta caactgaaaa ctgttggtgt gattcatctg cgttcacagc tggccaccaa
    18781 acgcgctgca ctgttggtga tgctgtgctt tttgctggcg ggttactggc tgtgggtcgg
    18841 tattgatggc tttgtactgc tcgcccagga tgctaacggt ccttccaatc cgttaatgaa
    18901 actggtggca gtgctacctg gtgcctggat gaataatttc gtcgaatcgc ccgttttgtg
    18961 gatcttcccg ctgctggggt tcttctgccc attgctgacg gtgatggcga tttatcgtgg
    19021 tcgcccgggt tggggatttt taatggcgtc attgatgcaa tttggcgtga ttttcacggc
    19081 aggcatcacg ctgttcccct ttgtcatgcc gtcaagcgtg agtccaatct ccagcctgac
    19141 gttgtgggac agcacttcca gtcagctgac gctgagcatt atgttggtaa tcgtgctgat
    19201 atttttgccc attgtgttgc tctacactct ctggagctac tacaaaatgt ggggacgcat
    19261 gacaacagaa actctccgcc gtaacgaaaa cgagttgtac taaggagcag gaacaatgtg
    19321 gtatttactt tggttcgtcg gcattttgtt gatgtgttcg ctctccaccc ttgtgttggt
    19381 atggctggac ccgcgtctga aaagttaacg aacgtaggcc tgatgcggcg cattagcatc
    19441 gcatcaggca atcaataatg tcagatatga aaagcggaaa catatcgatg aaagcgatct
    19501 taatcccatt tttatctctt ctgattccgt taaccccgca atctgcattc gctcagagtg
    19561 agccggagct gaagctggaa agtgtggtga ttgtcagtcg tcatggtgtg cgtgctccaa
    19621 ccaaggccac gcaactgatg caggatgtca ccccagacgc atggccaacc tggccggtaa
    19681 aactgggttg gctgacaccg cgcggtggtg agctaatcgc ctatctcgga cattaccaac
    19741 gccagcgtct ggtagccgac ggattgctgg cgaaaaaggg ctgcccgcag tctggtcagg
    19801 tcgcgattat tgctgatgtc gacgagcgta cccgtaaaac aggcgaagcc ttcgccgccg
    19861 ggctggcacc tgactgtgca ataaccgtac atacccaggc agatacgtcc agtcccgatc
    19921 cgttatttaa tcctctaaaa actggcgttt gccaactgga taacgcgaac gtgactgacg
    19981 cgatcctcag cagggcagga gggtcaattg ctgactttac cgggcatcgg caaacggcgt
    20041 ttcgcgaact ggaacgggtg cttaattttc cgcaatcaaa cttgtgcctt aaacgtgaga
    20101 aacaggacga aagctgttca ttaacgcagg cattaccatc ggaactcaag gtgagcgccg
    20161 acaatgtctc attaaccggt gcggtaagcc tcgcatcaat gctgacggag atatttctcc
    20221 tgcaacaagc acagggaatg ccggagccgg ggtggggaag gatcaccgat tcacaccagt
    20281 ggaacacctt gctaagtttg cataacgcgc aattttattt gctacaacgc acgccagagg
    20341 ttgcccgcag ccgcgccacc ccgttattgg atttgatcat ggcagcgttg acgccccatc
    20401 caccgcaaaa acaggcgtat ggtgtgacat tacccacttc agtgctgttt atcgccggac
    20461 acgatactaa tctggcaaat ctcggcggcg cactggagct caactggacg cttcccggtc
    20521 agccggataa cacgccgcca ggtggtgaac tggtgtttga acgctggcgt cggctaagcg
    20581 ataacagcca gtggattcag gtttcgctgg tcttccagac tttacagcag atgcgtgata
    20641 aaacgccgct gtcattaaat acgccgcccg gagaggtgaa actgaccctg gcaggatgtg
    20701 aagagcgaaa tgcgcagggc atgtgttcgt tggcaggttt tacgcaaatc gtgaatgaag
    20761 cacgcatacc ggcgtgcagt ttgtaatgca taaaaaagag cattcagtta cctgaatgct
    20821 ctgaggctga tgacaaacga agaactgtct aatgcgtaga ccggaaaagg cgttcacgcc
    20881 gcatccggcc actttcagtt ttactctttc tcggagtaac tataaccgta atagttatag
    20941 ccgtaactgt aagcggtgct ggcgcgttta atcacaccat tgaggatagc gcctttaata
    21001 ttgacgcctg cctgttccag acgctgcatt gacaaactca cctctttggc ggtgttcaag
    21061 ccaaaacgcg caaccagcag gctggtgcca acagaacgcc ccacgaccgc ggcatcactc
    21121 accgccagca tcggcggcgt atcgacaatc accagatcgt aatggtcgtt cgcccattcc
    21181 agtaattgac gcatccgatc gcgcatcagc agttcagacg ggttaggtgg cacctgaccg
    21241 cgagtaatca catcaaagcc tcctttgcca aaatgctgga tcactttgtt gagctcatct
    21301 ttacctgcca gatattccga caagccatgt tcattactca cggtaaacag gttatgcgaa
    21361 taaccacggc gtaagtcggc atcaataaat aacacttttt gatcggactg ggcgatcacc
    21421 gctgccagag ttgaactgac aaacgtttta ccactgtctg gcgtcgcacc ggtgatcatc
    21481 agaatgttat tctccgtctc catcatagcg aaatgcagac tggttcgtag cgcacgtacg
    21541 gcttccacag cagaatccgc cgggttatcc accgccagga aggggatatt tttagtacga
    21601 tggcgctgct gattagaaaa taaatttttc ttacgcagac gggtgcgttt atccagccac
    21661 tcggacattg ggatagtggc ataaacgctg atgccgtgct cttccagttg ttccggggct
    21721 tctacaccac gacgcaacat cgcacgcgcc agcacggcac ccacagaaat aaacaggcca
    21781 agaataaaac caagcaccac attcaacgct tttttcggtt tcactggctg cggctgagtg
    21841 actgccgggt cgataatccg cacgttacca atggcactgg atttcgaaat actcaactcc
    21901 tgctggcggt taagtaattg cagatatacc gcacggcccg cttctacgtc acgacttaaa
    21961 cgcaacactt cctgttgggt ggaaggcatt gccgataccc gcttattcag gcgtttgcgt
    22021 tcttgctcca gcgtctggcg tttttccagc agcgcacgat aagttgggtg atctttctta
    22081 tacagctggg agatctctgc ctcgcggaag gtcagctcat tgagttgatt atcaacgttc
    22141 acaatctgct caagaacggc tttggcttcc aggttaaggt caaccgaatc gcgctgctgg
    22201 cgataaacgt tgagtttttc ttccgcctgg tccagctcgc tgcgcacttc aggtaactgg
    22261 cgctgtaaga attcaaggct ttgtgaatcc tgcgccgcct ggcgagcgat attctgttgc
    22321 aaatagttgt tagcgatgct gttcagaata cgagtaatca actggggatc atcaccagtc
    22381 atggtaagtt ccagcatccc gctttcttta ctgcgttcgc taacggtaaa ggtttcctgc
    22441 aatgcgttaa tcgcttccag ttcggtacgc tggctcagga caaactgtgt tcctggtttg
    22501 gccttaatgt ccgcgatagt cagcgcaacg ccatcttttt ccagacgctg gccgaccata
    22561 ccattgacgg tgaactcttc accttccagt gtatagtggc cgttttcccc aaccgtgagt
    22621 gtcagttgct gatcctgacc attcagttgt ggaatatgca tccagctgat cgccagctca
    22681 cctggttttt ctttggttaa tctcgcccag ccgcgaccca caatcggaaa atacttctgc
    22741 tcaactatgt cgcgcagatt cagttcagca atggttttac cgagaatcat gcgcgattgc
    22801 agcagttgga tctccggtgc agactcgggc gatgagttag ggatcatatc gctcaggccg
    22861 ctgagaatgg cgttgccctg tttttgctca acctggacca gagtatctgc ctgataaatt
    22921 ggtgtactta acagcgagta agcgacagcg atcagcgtga ataacgcggt cacgctgata
    22981 ataaacttac ggtgatccca taactcgccg accagacgaa gcagatcgat ctcattttcc
    23041 tgagtgctgc ctggtggcgt attcatattt ttagttgtca tcgtatttta taaactcaaa
    23101 ttaccggctg aggcgcttcg cccattcctg actggcgcgc tccaacatac cgtagacatg
    23161 ttcaaatgcg tcctgacttt tacgataggg atccgggatc tctttctgtt ccagccattg
    23221 cccaaacagc attgtcttcc cgcggacctc gggagcgatt gcggtaacct gagcaatatg
    23281 ctctgactcc attgccagaa tcagatcgta atttcgtgcc atctcagcag tgagcttacg
    23341 tccggcatgt ccttcaagag atacgccatg attagcggca acatctgctg ctgtcgcatc
    23401 tgcagggtgt tttaccagac catgaacacc tgccgatttg acttttacgc ctggcagacg
    23461 tttacgcagc aagcgctcgc caatgggcga acggcaaatg ttgccggtac aaaccaccag
    23521 gattgagtta aattttagtt gggccatgtt tgaatccacc gtgaagtctc tgtcaggtca
    23581 tgcaccccgg aaatcgtcgg taccagcaga gaaatcacac ggttccaacg agccagcggc
    23641 gcagtagtga cataaacaat gtcgtaaggt tcaagctgga attccgttcc gagtatcatt
    23701 gccgatgcgt ccttcgcatt cagctgataa atattggcga ttttgccatt ctgcttgttt
    23761 tgcgttgcac gaataacaaa aatccccgtc gcatcagcga catcctgatt cataccctca
    23821 gcgttaccca gcgcttccgc cagggtcata ccgctgcggt ccattttcag cgtgctctgt
    23881 ttacccactt cacccatcac gaagactttc agatcatcgt tgcgcggaat aaataaaata
    23941 tcgcccgggt gcagcagttt gttctggcgc aagtcgccac gctgcatcag cgcatagagg
    24001 ttcactttgg tctttacgcc attctgggtg agcaccacgt tgcgccagtc tgcatctgcg
    24061 gtcagaccgc ccgcggcgtt aatcgcatcc atgatggtca gaggaatatt ggtaatcggc
    24121 tgctgacccg atttgctgac ttcgccggtg acgtacgctt tttgcgagcg gaacgccgcg
    24181 acgctgacat cgacttgcgg gctttcaatg actgaatcca gacgcgctgt aatctcgttg
    24241 cgtacctggg taagtgtttt cccggccact ttcaggcgac caatataggg gtagaaaatc
    24301 gcaccatcgg cgttaaccca gttgccggta tcactggcgc tacggtattg ccctgcgggg
    24361 gtggttagtt ccgggtgatc ccagaccgta accatcaaca catccccaat gccgatacga
    24421 tattcatagt ttgcgatttg ctgctccagc tccgggttag cctgcgacat aatcggtttg
    24481 gcgcgcaact gatcaatcaa tcctggcgtg acgggataga tattgaccat tttgtccagg
    24541 tcatactgat tgtcaggtag ttcaatgaca tccttgttac tggtcgataa attctgacca
    24601 ggaacaaggg tacatgctgt caaagacaga acagccaatg tcagtaccga aaacttaaaa
    24661 atgttctttt tcattggttt atatttatca gtcaatgtaa tgttatgaat tacgtcaggt
    24721 tattgtccaa ccggtacttc tcgctctgcc gtcattggat agagctggta tttgcgtgac
    24781 agcatttgtc caccatcacg cgtcaatggt gtccacgaaa ccaccgcgcg gttgcggtta
    24841 ggtccaatgg tcatcaagtc gaatggaatc gagatataaa aacctttact aaagccgcct
    24901 tcgccgtagt catctttaga tacgttactg attgccgccc atacccctac cgccacgccg
    24961 ctgtcaaagc gtttggcgac gtcgatcgtt gcgcctttat cttttgccag atattgccca
    25021 acgctaagtt tcatcagtac gccattgagc gtcggcgggt tccagtaagc cgtcacgaaa
    25081 cctgttggcg tggaataatc ggtgaaacgc atcatgttgt cccagtcacg ctgcttcacg
    25141 tagttaacgt ccacacccag cgcccagctg gcatctagcg ggcgataaag cagctcggaa
    25201 ccgacaccgg catacatcgt ttccagataa ccgccataca cctggccata gaaaccattg
    25261 cctaagtcag caaaatagtt cgcctgcaag ttgttgagat aaacgtcatt gcgaacgtag
    25321 tcacggatat gcgtgcgcac gcggggcagg gtagagtccg cgggcaacag cgaagactta
    25381 aacttgtcgt agttgttgta aatattggtg aaaataccgc catcaagcag caggtggtcg
    25441 gtaaaccagt agcgggcact ggacatcagc cccagctgga acatatagaa atcttccggg
    25501 ccgcccagcg actgtgaaag tgttgggttg aaagagtagc taaagcgatc ttcacgaata
    25561 cggtagcccc gaccaaaggc agaaagatct tctgcttcaa cacgttgttg ttgaagttgc
    25621 tctgattgac caggcgctgt accagccagc tgtttgcgca ggctggctac gtcggtttcg
    25681 gtagtcacca tcgccatatg ctcgcgcttt tgcgtcacgc taatcttctc aacgccttgc
    25741 ggcaggttat tcaccagaat ccggttggca cgatcgaccg cttcgcgaga atcacggtat
    25801 ttgtattgtt gaccagacat atacagcgtc ttatcgcgca gctgaatttc cggtgcttca
    25861 aaacctgcgt tgtacttcag cgcggtaagt tggttcgcta ctgtggtgta ctgcaatcct
    25921 tcagattcag gcgcaggttg atatgccggt tttggcgtat cgcgcagggc agggcgcaga
    25981 tcgttgaaat tggtccgtaa cgtgaagcca aacatcaacg tgttaccgcg ttcataactc
    26041 aggttgagat ctgcccagct ggcagcgcga taaactgcgc cgacgttgaa atggcttgcc
    26101 tgaggcagtt tgccagcgaa atcattctgg taattgttgc catcgtattc gagtttcaga
    26161 cgcaggggat tccacggcgt ttgatactca atgccgccaa agatggaagc cgggccacga
    26221 aagatatcgc taaagctgat atcgcccgca tcgtgagact ctgcgcgatg acaatattta
    26281 tcgctcaccc ggcaaaacgg gttggtaata ttgcccgcat taccggcgta gccccatgcc
    26341 atcccgaggg tgaaatcaaa tggccccgct tgcttgctgg ccaccagata ctcaccgtca
    26401 aacagacccg taccagcaat atcacgttta ccaaacgcca cttgcggtag ccagtaacct
    26461 tcttcccaca ggcgaagttt aaaatcgaat gatttgtctt tgtatgactg atcgccgctg
    26521 aaatcttccc actggctata tttgcgtgtg cgcacatccg tataacgaat ggtgccttcc
    26581 agccatggga acagcgccac ggaggtggag tagaaccggt attgatcgtt atcccggtag
    26641 ttgacgctga attcaccttc cggtgcgatg cgcgcatttg gcatctgcaa caatcctgtg
    26701 ccgccaaagt ctgattgcga cgaacccagc ggatccgggt aggttaatac ttcagcatga
    26761 caggcactgg agacggcaat ggccaggcag cttaaaagat aagaattctt cttcatcagt
    26821 caggaacacg ttgcgttaaa acagacacaa tctggtcatt taaatcagca tatttttcgg
    26881 gcagtacatg cgcagaaaag cccaaccaaa gctggctgcc aggcggtggt tccacatgtc
    26941 ttttattcca cagggcaaca ggggcgacga cagtctcacc ctcaggcgta atcaccataa
    27001 cgttattctt gtccgcgcct gcaaggcggg ggtgatcttg cagataatcg gtaacgctac
    27061 ggcctgcctg ccagggcaat tgcccagccc cagaaaccgc acccagcaga gtaatagtca
    27121 ccggacgctg tacggtatag agcgtatagt ccccgaccaa cgggggattg ctgttctcat
    27181 ccactcgaac aaaatcaggg tccagtttga ccggtaagcg accagtgata ttgagattga
    27241 gtaactgctg gcgcacggat ttaatcgttg ccgccacatc gtcgtcagct tctgcttccc
    27301 aggaagcaag ctgtgccatg acatgttggt agtctttaag cgctttagct ttcgccgcag
    27361 agtcggtcag caaggcacca ggccaccaga ggcgatcgcg cagttgcggt tgtgtcacca
    27421 actggacaac attttccacg gggccaacgg aaagtgtctg ttgttcgcca ggcagataaa
    27481 tagtcaccgt tccttgcgca aaggcatggg gtgtcattac gtaaagtacg ctggcaatga
    27541 aatacgactg taatttattc atggtgcggg tttaagaaac gtcatttcta cgggaataac
    27601 ccctgcgcct aacatttgcc gactttgacg aacctggcca gtagccgaat cgacccagaa
    27661 tgtgttttgc cactgttttt ctggccgcgt ggaagtcacc tcttcctgcc agacattaca
    27721 cagcacattg cgacccgcaa tattcagcgt ctctaatcca gcaaaggaaa aagtagaact
    27781 cagggtcgca gagcgaaaat ggttgtcttc actccagaga atatcgcgcg tccagcggct
    27841 gccatctttt attgccagcg cgttacgcag agggtcctgc ccggaatttg tcacttccag
    27901 cagattatta ttaagtttga cggtttttaa aagacgtcca ttgtgggtaa ccagcatggc
    27961 gttatcctgg gataaccatt tgctttgttc ttgttctata tatcccagta ccacaaagat
    28021 tcgttgccct tcattaaggc gtaaatacat cgtggaataa ggcaacgcct ggatctgctg
    28081 atccgctacg gtgatatcct gattatcgaa aaggctggcg cgaaatgtat cgaccatact
    28141 ttgctggctg tgcgtacatc ccgcaagaaa tagtgcgaaa atcgataaaa taagagggcg
    28201 cacctttaat ccttgaaagg ttaattaaaa aaatgcaaat ctctaaagcc cggtacgaat
    28261 atcgcaaccg ggtatcattt aactttaatt tcgacgcgtt aaagcagtat tagcgtgtag
    28321 tggacgtggt ggttgaggtg ttatgagaac cgccatcgcc actgtcattt gctgcaacaa
    28381 ctgccaacgt cgccacacca acagccgttg ccacaccgac aactgtcgcc gtgccgacag
    28441 cgccagcagc cacgccacca gtggtagtag cagtcgtggt tgcgccggta gtggtcgttg
    28501 tggtgccagt agtacccgtc gttgcctcgg tcccgtttgt tgcttcaggg gcagcaaacg
    28561 cagctggcgt cgtcaacatg aaggccataa ggattgcaga aagcttgtgt ttcataactt
    28621 ttcctttatt catcgcatgg acaatacgta cgcttgagat caggattgtc tactttgagt
    28681 ataacatcct tgtgaaatct ccctttcctc ataccgcttg cactatatac tgcgggtagg
    28741 aaaggcgcgc agagggaaat ataagattgt taactatccc cctctggaaa tacgacttgt
    28801 gagcataaga taaatcttag caaaatacaa at
//
LOCUS       DAPGUL010000054        28509 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.054, whole genome shotgun sequence.
ACCESSION   DAPGUL010000054 DAPGUL010000000
VERSION     DAPGUL010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 28509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28509
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.054"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            55..657
                     /locus_tag="RHX21_002519"
     CDS             55..657
                     /locus_tag="RHX21_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HDV1987682.1"
                     /translation="MVLLVVRTTNLLSLFVEWVKLFTDKVTRGGKMKKWMLAICLMFI
                     NEICQATDCFDLAGRDYKIDPDLLRAISWKESRYRVNAIGINPVTGYGSGLMQVDSQH
                     FNELARYGIKPEHLTTDPCMNIYTGAYYLAIAFKKWGVTWEAVGAYNAGFRKTERQNQ
                     RRLAYASDVYRIYTGIKSSKGIRLPATKKSLPEINSVQNN"
     gene            complement(954..1775)
                     /locus_tag="RHX21_002520"
     CDS             complement(954..1775)
                     /locus_tag="RHX21_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HDV1987683.1"
                     /translation="MRLASRFGRYNSIRRERPLTDDELMQFVPSVFSGDKHESRSEHY
                     TYIPTINIINKLRDEGFQPFFAYQSRVRDLGRREYSKHMLRLRREGHINGQEVPEIIL
                     LNSHDGSSSYQMIPGIFRFVCTNGLVCGNNFGEIRAPHKGDIVGQVIEGAYEVLGVFD
                     KVTDNMEAMKEIHLNSDEQHLFGRAALMVRYEDENKTPVTPEQIITPRRREDKQNDLW
                     TTWQRVQENMIKGGLSGRSASGKNTRTRAITGIDGDIRINKALWVIAEQFRKWKS"
     gene            complement(1895..2092)
                     /locus_tag="RHX21_002521"
     CDS             complement(1895..2092)
                     /locus_tag="RHX21_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001434948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987684.1"
                     /translation="MEFSSLTELKKYRKSHPEKMAFSYSYALSQGVDKQFRHINIAEA
                     DHFKQFLRQIKRAGLDIRAIC"
     gene            complement(3102..3260)
                     /locus_tag="RHX21_002522"
     CDS             complement(3102..3260)
                     /locus_tag="RHX21_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="HDV1987685.1"
                     /translation="MKLPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGHREVAA
                     FMAYESGK"
     gene            complement(3360..4729)
                     /locus_tag="RHX21_002523"
     CDS             complement(join(3360..4249,4249..4729))
                     /locus_tag="RHX21_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611947.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS150 family transposase"
                     /protein_id="HDV1987686.1"
                     /translation="MSKPKYPFEKRLEVVNHYFTTDDGYRIISARFGVPRTQVRTWVA
                     LYEKHGEKGLIPKPKGVSADPELRIKVVKAVIEQHMSLNQAAAHFMLAGSGSVARWLK
                     VYEERGEAGLRALKIGTKRNIAISVDPEKAASALELSKDRRIEDLERQVRFLETRLMY
                     PKKAESLSSSHEKVKVLNELRQFYPLDELLRAAEIPRSTFYYHLKALSKPDKYADVKK
                     RISEIYHENRGRYGYRRVTLSLHREGKQINHKAVQRLMGTLSLKAAIKVKRYRSYRGE
                     VGQTAPNVLQRDFKATRPNEKWVTDVTEFAVNGRKLYLSPVIDLFNNEVISYSLSERP
                     VMNMVENMLDQAFKKLNPHEHPVLHSDQGWQYRMRRYQNILKEHGIKQSMSRKGNCLD
                     NAVVECFFGTLKSECFYLDEFSNISELKDAVTEYIEYYNSRRISLKLKGLTPIEYRNQ
                     TYMPRV"
     gene            4786..4974
                     /locus_tag="RHX21_002524"
     CDS             4786..4974
                     /locus_tag="RHX21_002524"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="protein sok"
                     /protein_id="HDV1987687.1"
                     /translation="MKINLLRGYLLSATQHGNKPPSRHEAESLKRRAHHSPYTCTLTT
                     LTFPENNPLIQTVHGKSV"
     gene            complement(4986..5705)
                     /locus_tag="RHX21_002525"
     CDS             complement(4986..5705)
                     /locus_tag="RHX21_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001763821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid SOS inhibition protein A"
                     /protein_id="HDV1987688.1"
                     /translation="MSARSQALVPLSTEQQAAWRAVAETEKRRHQGNTLAEYPYAGAF
                     FRCLNGSRRISLSDLRFFMPSLTAEELHGNRLQWLYAIDVLIETQGEVCLLPLPGDAA
                     ERLFPSVRFRVRERSRHKSALVMQKYSRQQAREAEQKARAYQALVTQAEIELAFHSPE
                     TVGSWHARWSDRVAEHDLETLFWQWGERFPSLAGMERWQWQDMPFWQVIAEAGMAARV
                     VGHAVREMERWMVPNKLREAA"
     gene            complement(5702..6136)
                     /gene="psiB"
                     /locus_tag="RHX21_002526"
     CDS             complement(5702..6136)
                     /gene="psiB"
                     /locus_tag="RHX21_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000845953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugation system SOS inhibitor PsiB"
                     /protein_id="HDV1987689.1"
                     /translation="MKTELTLNVLQTMNAQEYEDIRAAGSDERRELTHAVMRELDVPD
                     NWTMNGEYGSEFGGFFPVQVRFTPAHERFHLALCSPGDVSQVWVLVLVNAGGEPFAVV
                     QVQRRFAPEAVSHSLALAASLDAQGYSVSDIIHILMAEGGQA"
     gene            complement(6191..8149)
                     /locus_tag="RHX21_002527"
                     /pseudo
     CDS             complement(6191..8149)
                     /locus_tag="RHX21_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052657.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
     gene            complement(8215..8448)
                     /locus_tag="RHX21_002528"
     CDS             complement(8215..8448)
                     /locus_tag="RHX21_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF905 family protein"
                     /protein_id="HDV1987690.1"
                     /translation="MSEYFRILQGLPDGPFTRKHAEAVAAQYRNVFIEDDHGEQFRLV
                     VRNNGAMVWRTWNFEDGAGYWMNHVIRDFGILK"
     gene            complement(8511..8963)
                     /locus_tag="RHX21_002529"
     CDS             complement(8511..8963)
                     /locus_tag="RHX21_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDV1987691.1"
                     /translation="MAVRGINKVILVGRLGKDPEVRYIPNGGAVANLQVATSETWRDK
                     QTGEMREQTEWHRVVLFGKLAEVAGEYLRKGAQVYIEGQLRTRSWEDNGITRYVTEIL
                     VKTTGTMQMLGRVAGAQTQPEEGQQFSGQPQPQPPEGEDYGFSDDIPF"
     gene            complement(8989..9195)
                     /locus_tag="RHX21_002530"
     CDS             complement(8989..9195)
                     /locus_tag="RHX21_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDV1987692.1"
                     /translation="MYIPQKFLPKSRQKLLRSAPGQSFPSVAVMPLAAKVLKKVMVNT
                     GGNKRQVPAKRQNRGSRNSKDDGG"
     gene            complement(9606..9815)
                     /locus_tag="RHX21_002531"
     CDS             complement(9606..9815)
                     /locus_tag="RHX21_002531"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987693.1"
                     /translation="MPVSPRREKTRAGGAERGRAHAPPLSLRGRSDGGFCFFMPVICL
                     LLMMLLFLLLLLLLLLLLFFFFLLL"
     gene            complement(9841..10404)
                     /locus_tag="RHX21_002532"
     CDS             complement(9841..10404)
                     /locus_tag="RHX21_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDV1987694.1"
                     /translation="MHSQLRERIRLMRARLDNAAPVAEIRAESQLFVTPAPVCDRLVM
                     LAEISNRDHILEPSAGTGAILRAIRDTAPGAMCDAVEINSGLVRYLRENFNGVRVQCG
                     DFMEWQPVQYYSRVIMNPPFSHGQDIRHILRAFSLLRPGGVLVAVCLNGPRQQEKLLP
                     FSDVREELPRGTFAYTDVPTMIIRLRA"
     gene            complement(10452..11813)
                     /locus_tag="RHX21_002533"
     CDS             complement(10452..11813)
                     /locus_tag="RHX21_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3560 domain-containing protein"
                     /protein_id="HDV1987695.1"
                     /translation="MTLAAITMTAPEAASPVQMYRATYSPDDNKLRLYAVSRLDSETY
                     KKVHDAGFRWAPKQALFVAPAWTPGREDVLLSLAGEIEDEDSTLAERQEARAERFTGY
                     SGKRASESAQALDEVERLAAMIPPGQPILVGHHSERRARRDAQRIENGMKRAVMLFER
                     AEYWEERARSALLHAKYKERPDVRWRRIKKIEADLRKAEKTIAQSQKYLTMWRAESLD
                     LNMAKLISSHDHISACFPLDTYPRPAEKSQYEGSRSLWSALDDDIITTEQAREIAIRC
                     HERQIQHQQRWVNHYQNRLIYERAMLDESGGVVTRTQDFEPGGQVFSRGEWLTIIRVN
                     KSNGAVSSVTTPNYSFLGYSGTMKVTPDRITDYKAPSAEEAAVASQAAKRPPVVNYPG
                     EGFREMTKAQWAALPRDCKAVRSVAEAEDHGAYRYRRTMDNNFRLVNVYITDMKITEI
                     PQK"
     gene            complement(11865..12095)
                     /locus_tag="RHX21_002534"
     CDS             complement(11865..12095)
                     /locus_tag="RHX21_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987696.1"
                     /translation="MTVSIVSPSAAAVKPRRHPRFRREDIPAPEIDPVLKAFGRHIAR
                     SFHRGRGVHIPAMKNTAFGQVLRTLELKRAFN"
     gene            complement(13130..13321)
                     /locus_tag="RHX21_002535"
     CDS             complement(13130..13321)
                     /locus_tag="RHX21_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987697.1"
                     /translation="MNISTETREILRNYRAVINARRREMGQKPLTTAQIVDEICDFVV
                     NQQAVFLGGHYILQGSRNR"
     gene            complement(13318..13740)
                     /locus_tag="RHX21_002536"
     CDS             complement(13318..13740)
                     /locus_tag="RHX21_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1380 family protein"
                     /protein_id="HDV1987698.1"
                     /translation="MYCTVKEIIREVLDTDVPDSECVFAVVLTRGDVRHIAQDWSLTD
                     DELETVMQRLDDAFEYGADVSVVHGVVRELMEEKRASRQVTVPAVMLEKVMALAGSEM
                     KRLYAVGSENGGDGDAFVREEREAMDVVLKALDGETMS"
     gene            complement(13787..14089)
                     /locus_tag="RHX21_002537"
     CDS             complement(13787..14089)
                     /locus_tag="RHX21_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HDV1987699.1"
                     /translation="MMPEYQGGFWHFIRLPDGGGYMMPDGDRFHMVNGANWFDRTVSA
                     DAAGIILTSLVINRQLWLYHDSGDAGLTQLYRMRDAQLWRHIEFHLECNAIYAALD"
     gene            complement(14629..15399)
                     /locus_tag="RHX21_002538"
     CDS             complement(14629..15399)
                     /locus_tag="RHX21_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987700.1"
                     /translation="MNETLNALICRHARNLLLAQGWPEETDVDQRNPNHPGWISIYVR
                     LDAPRLATLLINRHGGVLPPHLASAIQKLTGTGAELVLSGSQWQSLPVLPADGTQVSF
                     PYAGEWLAEDEIRAVLAAVRDAIRSICYQVADDARRIRAALTTTGQTLLTRQTRRFRL
                     VVKESDHPCWLDEDDENLPVVLDAIVNRGARFSSVEMYLVSDCIEHILSSGLACDVLR
                     IPDEPPRRWFDRGVLREVVRKARAEIRSMADALAKIRK"
     gene            complement(15444..15878)
                     /locus_tag="RHX21_002539"
     CDS             complement(15444..15878)
                     /locus_tag="RHX21_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001562898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1380 domain-containing protein"
                     /protein_id="HDV1987701.1"
                     /translation="MYGTCETLCRELAVKYPGDMPLMLVIWSPEEIQALADGMDISLS
                     DHEIRTVLARLEDIPEDQRTESGISSGVAMEIINNVSENRQVTVPAELLASLIQTAEQ
                     ALWKREWAARDHGLAVPECVTRRQAVINQARTLLKNNTREND"
     gene            complement(15892..16113)
                     /locus_tag="RHX21_002540"
     CDS             complement(15892..16113)
                     /locus_tag="RHX21_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987702.1"
                     /translation="MNYAGHEKLRAEVAEVANAMCDLRTTMNEMEQRYSFNADTLPER
                     LVRQTLFRANRLLMEAYTEILELDACFKD"
     gene            complement(16114..16797)
                     /locus_tag="RHX21_002541"
     CDS             complement(16114..16797)
                     /locus_tag="RHX21_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methylase"
                     /protein_id="HDV1987703.1"
                     /translation="MSRFILGDCVRVMATFPDNAVDFILTDPPYLVGFRDRSGRTIAG
                     DKTDEWLQPACIEMFRVLKKDALMVSFYGWNRVDRFMAAWKNAGFSVVGHLVFTKNYT
                     SKAAYVGYRHECAYILAKGRPRLPPNPLPDVLGWKYSGNRHHPTEKPVTSLQPLIESF
                     THPNAIVLDPFAGSGSTCVAALQSGRRYIGIELLEQYHRAGQQRLAAVQRAMQQGAAN
                     DDWFMPEAA"
     gene            complement(16873..17184)
                     /locus_tag="RHX21_002542"
     CDS             complement(16873..17184)
                     /locus_tag="RHX21_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858330.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987704.1"
                     /translation="MNSDGDGRATARFFSDKGCRRAPLFTAPADAARHKRCLWSVSRV
                     RRARDGRFYRSRLAPVTVYASPSPFSDERPSSRFRGIALPSKRRRLRYSTVGLTRYRT
                     R"
     gene            complement(17181..18083)
                     /locus_tag="RHX21_002543"
     CDS             complement(17181..18083)
                     /locus_tag="RHX21_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1281 domain-containing protein"
                     /protein_id="HDV1987705.1"
                     /translation="MHFSGEPAQIAEIKRLASGAVTPLYRRATDEGIQLFLAGSAGLL
                     QTTEDVRFEPCPGLTAAGRGVVSPENIAFTRWLTHLQNGVLLDEQNCLMLHELWLQSG
                     TGQRRWEGLPDEVRETITVHFTAKRGDWCGFWSNEDVSVWWNRLCDNVLPEKTMPFDL
                     LTVLPTRLDVEVNGFNGGVLNGVPSAYHWYTEQYGVKWPVGYEVNISSQGDNFIQVDF
                     DTPWCQPESDVIAELSRRFSCTLEHWYAEQGCNFCGWQRYERGELVDVLWGELEWSSP
                     TDDDELPEVTGPAWIVDKVAHYGG"
     gene            complement(18821..19792)
                     /locus_tag="RHX21_002544"
     CDS             complement(18821..19792)
                     /locus_tag="RHX21_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family plasmid partition
                     protein"
                     /protein_id="HDV1987706.1"
                     /translation="MKRAPVIPKHTLNTQPVEDTSLSTPAAPMVDSLIARVGVMARGN
                     AITLPVCGRDVKFTLEVLRGDSVEKTSRVWSGNERDQELLTEDALDDLIPSFLLTGQQ
                     TPAFGRRVSGVIEIADGSRRRKAAALTESDYRVLVGELDDEQMAALSRLGNDYRPTSA
                     YERGQRYASRLQNEFAGNISALADAENISRKIITRCINTAKLPKSVVALFSHPGELSA
                     RSGDALQKAFTDKEELLKQQASNLHEQKKAGVIFEAEEVITLLTSVLKTSSASRTSLS
                     SRHQFAPGATVLYKGDKMVLNLDRSRVPTECIEKIEAILKELEKPAP"
     gene            complement(19792..20958)
                     /gene="sopA"
                     /locus_tag="RHX21_002545"
     CDS             complement(19792..20958)
                     /gene="sopA"
                     /locus_tag="RHX21_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid-partitioning protein SopA"
                     /protein_id="HDV1987707.1"
                     /translation="MKLMETLNQCINAGHEMTKAIAIAQFNDDSPEARKITRRWRIGE
                     AADLVGVSSQAIRDAEKAGRLPHPDMEIRGRVEQRVGYTIEQINHMRDVFGTRLRRAE
                     DVFPPVIGVAAHKGGVYKTSVSVHLAQDLALKGLRVLLVEGNDPQGTASMYHGWVPDL
                     HIHAEDTLLPFYLGEKDDVTYAIKPTCWPGLDIIPSCLALHRIETELMGKFDEGKLPT
                     DPHLMLRLAIETVAHDYDVIVIDSAPNLGIGTINVVCAADVLIVPTPAELFDYTSALQ
                     FFDMLRDLLKNVDLKGFEPDVRILLTKYSNSNGSQSPWMEEQIRDAWGSMVLKNVVRE
                     TDEVGKGQIRMRTVFEQAIDQRSSTGAWRNALSIWEPVCNEIFDRLIKPRWEIR"
     gene            complement(21546..22301)
                     /gene="repE"
                     /locus_tag="RHX21_002546"
     CDS             complement(21546..22301)
                     /gene="repE"
                     /locus_tag="RHX21_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepE"
                     /protein_id="HDV1987708.1"
                     /translation="MAETAVINHKKRKNSPRIVQSNDLTEAAYSLSRDQKRMLYLFVD
                     QIRKSDGTLQEHDGICEIHVAKYAEIFGLTSAEASKDIRQALKSFAGKEVVFYRPEED
                     AGDEKGYESFPWFIKRAHSPSRGLYSVHINPYLIPFFIGLQNRFTQFRLSETKEITNP
                     YAMRLYESLCQYRKPDGSGIVSLKIDWIIERYQLPQSYQRMPDFRRRFLQVCVNEINS
                     RTPMRLSYIEKKKGRQTTHIVFSFRDITSMTTG"
     gene            complement(23023..23829)
                     /locus_tag="RHX21_002547"
     CDS             complement(23023..23829)
                     /locus_tag="RHX21_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="HDV1987709.1"
                     /translation="MSGSVIHSQSAAMVPAVYSAGQSAQLPVAIDYPAALALRQMSMV
                     HDELPKYLLAPEVSALLHYVPDLRRKMLLATLWNTGARINEALALTRGDFSLTPPYPF
                     VQLATLKQRTEKAARTAGRMPAGQQTHRLVPLSDSWYVSQLQTMVATLKIPMERRNRR
                     TGRTEKARIWEVTDRTVRTWIGEAVAAAAADGVTFSVPVTPHTFRHSYAMHMLYAGIP
                     LKVLQSLMGHKSISSTEVYTKVFALDVAARHRVQFAMPESDAVAMLKQLS"
     gene            complement(23830..24135)
                     /gene="ccdB"
                     /locus_tag="RHX21_002548"
     CDS             complement(23830..24135)
                     /gene="ccdB"
                     /locus_tag="RHX21_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin CcdB"
                     /protein_id="HDV1987710.1"
                     /translation="MQFKVYTYKRESRYRLFVDVQSDIIDTPGRRMVIPLASARLLSD
                     KVSRELYPVVHVGDESWRMMTTDMASVPVSVIGEEVADLSHRENDIKNAINLMFWGI"
     gene            complement(24137..24355)
                     /gene="ccdA"
                     /locus_tag="RHX21_002549"
     CDS             complement(24137..24355)
                     /gene="ccdA"
                     /locus_tag="RHX21_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin CcdA"
                     /protein_id="HDV1987711.1"
                     /translation="MKQRITVTVDSDSYQLLKAYDVNISGLVSTTLQNEARRLRAERW
                     QAENQEGMAEVARFIEMNGSFADENRDW"
     gene            24983..25213
                     /locus_tag="RHX21_002550"
     CDS             24983..25213
                     /locus_tag="RHX21_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HDV1987712.1"
                     /translation="MRTVSIFKNGNNRAIRLPRDLDFEGVSELEIVREGDSIILRPVR
                     PTWGSFLELEKADPDFMTEREDVVSDEGRVNL"
     gene            25210..25626
                     /locus_tag="RHX21_002551"
     CDS             25210..25626
                     /locus_tag="RHX21_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family
                     toxin"
                     /protein_id="HDV1987713.1"
                     /translation="MNKIYMLDTNICSFIMREQPEALLKHLEQSVLRGHRIVVSAITY
                     SEMRFGATGPKASPRHVQLVDAFCERLDAVLPWDRAAVDATTEIKVALRLAGTPIGPN
                     DTAIAGHAIAACAILVTNNVREFERVPGLVLEDWVR"
     gene            25701..27266
                     /locus_tag="RHX21_002552"
     CDS             25701..27266
                     /locus_tag="RHX21_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDV1987714.1"
                     /translation="MPLITRLMLQNFKKFPELDLRFSNDRNILVGDNESGKSTILLAL
                     DLVLSDSRHRVEALGVESLLSQSAVRHFQEGERRADQLPVLTADVFLSNGGEPDLNGR
                     QNLAGIDADGLRMRIAPMMEEYGQDIHHVLQQDPDNFPYEYYSVQFSTFSGGHFAGFR
                     RYLRHLFLDSARIDNEHAAQEYTRTVYSVNVPVADRYRLENSYRQQKMHFCARHLSAI
                     NDTLKTYQFGVRSGAKSGLEANLDITEDGISIRHRGKGRQCFIKTEFALQRHQQQGGE
                     IHALLLEEPENHLSHVSMKRLVNQLATERQTQVFIATHSSHISSRLDLRKAILLGATR
                     PVLMNELSAETAAFFMKAPDNNVLEFALARRVLLVEGDAEFILIEAFYHRLYGRAPED
                     DGVHIIAIGGTSFRRYLELARLLENRVAALRDNDGNYQQNCDERYADVLCSRSRVFAD
                     HDNSRSTFEICLYQDNADLCDALFRGTRRTLTVQDYMLANKAEAAFQLLQLHAEKLTV
                     PDYIQEALAWIRE"
     gene            27251..28273
                     /locus_tag="RHX21_002553"
     CDS             27251..28273
                     /locus_tag="RHX21_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrD"
                     /protein_id="HDV1987715.1"
                     /translation="MDKRVIFAVAGSGKTTLLIRRLREDRRTLILTFTVNNEAHLRAQ
                     IIRRFGYIPYGIRVMTWFEFLHGFCFRPFLQEQLSSRGLSFNQPPSRIPRTNIRHYQD
                     PAGRLYHRRLAHLLTARGLLPDIRTRLARYYDELFVDEVQDFAGHDFNFLLELCRAEI
                     SVLCCGDFYQHTFDTSRDGNVNATLHEDITRYEARFRAAGIMVDCETLSRTWRCSATV
                     CEFITGQLNIRISAHGTHTTQIEIVTDEARSAALHADNTMIKLFYREHHRYGCHSMNW
                     GGSKGLDHFQDVCIVMGANHWMRLIQQKLAALPPSSRNRLYVACSRARGNIYFIPESH
                     LRRFRN"
BASE COUNT         6719 a         7973 c         7262 g         6555 t
ORIGIN      
        1 cataactctc tatttataaa gaaaaatcag caaaaacttg tttttgcgtg gggtgtggtg
       61 cttttggtgg tgagaaccac caacctgttg agcctttttg tggagtgggt taaattattt
      121 acggataaag tcaccagagg tggaaaaatg aaaaaatgga tgttagccat ctgcctgatg
      181 tttataaatg agatctgcca ggccactgat tgctttgatc ttgcaggccg ggattacaaa
      241 atagatcctg atttactgag agcaatatca tggaaagaat cccgttaccg agttaatgcc
      301 atcggtatta atccggtaac gggatatggc agcggactga tgcaggtaga ttcccagcat
      361 tttaacgaac tggcccgcta cggaattaag ccagaacatc tgacaacaga tccctgcatg
      421 aacatttata ccggtgctta ttatctggca atagcattta aaaaatgggg cgtcacctgg
      481 gaggccgttg gtgcatacaa tgccggattc aggaaaaccg aacgccagaa ccagagacgt
      541 cttgcctacg catcagatgt ttaccggatt tatactggga taaaaagcag taaaggtatc
      601 cggcttccgg ccacgaagaa atcacttccg gaaattaaca gcgtgcagaa caattaatct
      661 tacagacatt gtcagatacc ggttatgccg caaaagcggc atggaaggcc acacacaaaa
      721 atatcatatg agtgacaata ctgactggcc gaagccccgc gaagcgggaa cccatcttat
      781 atatacccgg taactgcgca gcctcctgcc agaccatctt tcgcgggcac aatatttaca
      841 gacaaccgga aagccggttg atgaaattga ggtatatcag acgacacagc aatgccgaaa
      901 aatgataata taagtaaagc cccgaaaatt tttccggggc tttacttata ttatcatgac
      961 ttccactttc tgaactgttc ggcaatcacc cataacgcct tgttgattct tatatcacca
     1021 tcaatacctg taatggctct tgtcctagta tttttcccgg aggcacttcg ccccgataat
     1081 ccacctttta tcatattctc ctgaacccgc tgccaggttg tccagagatc gttctgtttg
     1141 tcttcccgac gacggggagt aattatctgt tcaggtgtca ctggcgtttt attttcatct
     1201 tcatacctga ccatcagtgc agctctgcca aataaatgtt gctcgtcact gttaagatga
     1261 atttctttca tcgcctccat attatcagtg accttatcaa agacaccgag cacttcatac
     1321 gctccctcga taacctgccc gacaatatca cctttatgtg gagcgcggat ttcgccaaaa
     1381 ttatttccgc acaccaggcc atttgtgcag acaaaacgaa aaattccggg gatcatctga
     1441 taactggatg aaccatcatg tgaattaagc aggataattt caggaacttc ctgtccgtta
     1501 atatgccctt ccctgcgaag acgtaacata tgtttactgt attcgcgacg tcccaaatca
     1561 cgaacccgac tctgataggc aaagaatggc tggaaacctt catcacgtaa cttattgatg
     1621 atattgattg ttggaatata cgtataatgt tcactccggg actcatgttt atcaccggaa
     1681 aataccgaag gcacgaactg cattaattca tcatccgtta aaggacgttc acggcggatg
     1741 gaattatacc gaccaaaacg ggaagctaat cgcataacag ctactccttt atgaaagaat
     1801 aaatttaata aaaaattttt ccgcttaata tcatcccccc ccgatctcta ttaacaagat
     1861 tgcaacaatc aggagggata ttcatcacat ccggtcagca gatcgcccgg atatcgaggc
     1921 cggcacgctt aatctgacgc aggaactgtt tgaagtgatc ggcttccgca atgttgatat
     1981 ggcggaactg cttatccaca ccctgactga gcgcgtagct ataactgaag gccatctttt
     2041 ccgggtggct tttgcgatat tttttcagct cagtcaggct gctgaattcc aggacgtccc
     2101 actcttcccc ggtgtttttt tcttcccggc aacaagaagc gtgtacgacg cggtgttaac
     2161 gtggatattt cgggtactca tcctgctttc tcctctatct ggttttcagc ccccatcatc
     2221 tgttgagttt cgggagccgc ggttttgacg ttttgcgggg acctgccttt tgttccctcc
     2281 ggtattcacc atcacctgtt tgagaacctt cgccgcatgg ggcatcactg ccacggccgg
     2341 aaacgactgt ccgggggcag accgcaaaag tttttgcctg cttctgggca aaaacttttg
     2401 cgggatgtgc atttcacccc tggactggcg gagacggttg tggctgtcta tgcccccggc
     2461 gacaggggct taaacaggtg aatggcaccg gacacaacaa cgggcaggga cccgccgcaa
     2521 cgacgtgaag cgcggtttgc gaaacggcgt tgcgccttac atcccggcgg ccttttgccg
     2581 ggatgccagg agcgcaggcc acggcgcgac agaggcggcg cgaccggaac ggtcgctgca
     2641 agcccggggt tttcacgcat cggaccgtag cgacagcccg aaaccgcgcc agcgggttcg
     2701 gcggagactg gcaggtgcgc cagcagctgc ctgtcggagt cgggcctgac gaccggatgc
     2761 cgccaggcag ccgggagccg aaggtgcgcc ggcagacagg acaacactgc agtagtcaga
     2821 atcagagcag gaagaaaaag agaataatca cagggaaggt gatgtgattt ctgacaagcc
     2881 ataaccagag aaggcggggg aaaagaacgg gcgccgcagg cgcgcgttca tccccgttcc
     2941 tgaagggaaa cgaccttcct gaagtcaggt tgttcatgcc cgtacaacat cagcaaggag
     3001 aaaggggcta ccggcgaacc agcagcccct ttataaaggc gcttcagtag tcagaccagc
     3061 atcagtcctg aaaaggcggg cctgcgcccg cctccaggtt gctacttacc ggattcgtaa
     3121 gccatgaaag ccgccacctc cctgtgtccg tctctgtaac gaatctcgca cagcgatttt
     3181 cgtgtcagat aagtgaatat caacagtgtg agacacacga tcaacacaca ccagacaagg
     3241 gaacttcgtg gtagtttcat ggccttcttc tccttgcgca aagcgcggta agaggctatc
     3301 ctgatgtgga ctagacatag ggatgcctcg tggtgtactg accccaaaaa gttggacagt
     3361 taaacacgag gcatataggt ctgattccga tattcaattg gagtcagacc ttttaatttc
     3421 aggctaattc ttctgctgtt gtagtattca atatattccg taacagcatc cttcagttcg
     3481 cttatattac tgaactcatc aagataaaaa cactccgact ttaaggttcc aaagaaacac
     3541 tccaccacag cattatccag acaattgcct tttctggaca tgctttgttt aataccatgt
     3601 tctttaagga tattttgata tcttctcata cgatactgcc atccctggtc agagtgcaga
     3661 acaggatgct cgtgaggatt aagctttttg aatgcctgat cgagcatatt ctcaaccatg
     3721 ttcatcactg gtctttccga aaggctgtaa gaaataactt cgttgttgaa gagatctatt
     3781 actggagaca aatacagctt gcgcccattg actgcaaatt cagtaacatc ggtaacccac
     3841 ttctcgtttg gccgcgtagc cttgaaatct ctttggagaa cattaggggc ggtttgccct
     3901 acctctcctc tgtaagagcg gtatcgcttg accttaatcg ctgctttaag tgagagggtt
     3961 cccatcaggc gctgaacagc tttatggtta atctgtttcc cttctcgatg aagagacagc
     4021 gttaccctac ggtatccgta tcggcctcta ttctcgtgat aaatctcact aatacgcttt
     4081 ttaacgtccg catacttgtc aggcttgctg agagccttta gatgataata aaacgtactg
     4141 cgcggtatct ccgcagccct gagaagctca tcaagaggat aaaactgcct tagctcgttg
     4201 agtactttca ctttttcgtg ggatgagcta aggctttcag cttttttaga tacataagcc
     4261 gcgtttcaag aaatcgaact tgcctttcaa gatcctcaat gcgtcggtct tttgacagct
     4321 ccaatgctga tgccgctttt tctggatcaa ctgatattgc aatgtttctt ttggtgccaa
     4381 tcttgagcgc gcgtaaacca gcttctccgc gctcttcata gaccttcagc cacctggcta
     4441 cagaaccact accagcaagc ataaagtgag cagcagcctg attaagggac atgtgctgct
     4501 cgatcacagc tttcacgacc ttaatacgca actctggatc agcactaacg cctttaggtt
     4561 tgggaattaa acctttttct ccatgttttt catagagggc aacccatgtc ctgacctggg
     4621 ttcgggggac accaaaacgt gccgagatga tcctgtaacc atcatcagtt gtgaagtagt
     4681 gattcacgac ttcaaggcgc ttttcaaaag ggtattttgg ctttgacata ttaggggcta
     4741 ttccatttca tcgtccaaca aaatgggtgc agtacatggt ggttaatgaa aattaactta
     4801 ctacggggct atcttctttc tgccacacaa cacggcaaca aaccaccttc acgtcatgag
     4861 gcagaaagcc tcaagcgccg ggcacatcat agcccatata cctgcacgct gaccacactc
     4921 actttccctg aaaataatcc gctcattcag accgttcacg ggaaatccgt gtgattgttg
     4981 ccgcatcacg ctgcctcccg gagtttgttc ggcaccatcc accgctccat ctcacgaaca
     5041 gcatgaccga ccacccttgc cgccatacca gcctctgcga tgacctgcca gaatggcata
     5101 tcctgccact gccagcgttc cattccggcc agtgacggaa aacgctcgcc ccactgccag
     5161 aacagggttt ccaggtcatg ctctgccacc cggtcactcc agcgtgcatg ccagcttccg
     5221 actgtttccg gcgaatggaa tgccagttcg atttcagcct gagtgaccag cgcctggtac
     5281 gcacgggctt tctgctctgc ctccctcgcc tgctggcggc tgtacttctg catgaccagc
     5341 gcggatttat ggcgactgcg ttccctgaca cgaaaccgca ccgacgggaa caagcgctct
     5401 gctgcatcac cgggaagggg aaggaggcag acctcgccct gtgtttcaat cagcacatcg
     5461 atggcataca gccactgaag acggttgccg tgcagttctt ctgcggtcag ggacggcatg
     5521 aaaaatcgca ggtcagacag cgatatcctg cggcttccgt tcagacagcg gaaaaacgcc
     5581 cccgcatacg gatattcagc cagcgtgtta ccctgatggc ggcgtttttc ggtctccgcc
     5641 accgcccgcc atgcggcctg ttgctctgtg ctgagaggaa ccagtgcctg tgaacgtgcg
     5701 ctcatgcctg acctccttcc gccatcagga tatggatgat gtcactgacg ctgtacccct
     5761 gcgcgtccag tgacgctgcc agtgccagtg aatggctgac ggcttccggt gcaaaccgcc
     5821 gctgcacctg aaccaccgca aacggctcac caccggcatt caccagaacc agcacccaga
     5881 cctgagagac atcgcccggt gaacataacg ccaggtgaaa acgttcgtgg gcaggcgtga
     5941 aacggacctg gacggggaaa aagccgccaa actcgctgcc gtactcgccg ttcatcgtcc
     6001 agttatccgg cacatccagc tcccgcatca cggcgtgagt cagttcacgg cgttcatcac
     6061 ttccggcagc ccggatatct tcatattcct gtgcgttcat ggtctgcagg acattcaggg
     6121 tcagttcagt tttcatcacg gtatctccct tgctgccgcc ccgtctccgg cggggcggtg
     6181 tggtttttca tcaggcggca tcagccaggt tatcggtgcg ttcagtggca tccgtctgtg
     6241 ggcgtggtgc acacatccag ccaggcaccc agcggttgtc tttcatgtgg aactctgcat
     6301 gttcagccgc atcgcctttc ttcatcttct ccgcgtcccg tgcagcaccg gacaggccgg
     6361 cctcattcag agctgcgata atctgcggct ttttcaggtg tccgaagaag tttgcttttg
     6421 tcggctgcca ccagtcgcgc atgtggaatc cgatagcggt ttccagcggg tcaagcggac
     6481 tgcgtgacga gtgaccacac tcgcgggtct gaacgccgtg gatgctgcac gcagtgcaga
     6541 aactgagcag ggataacagc acctcctggc tgagtgacag gaacgtcgtc atgtcccgtg
     6601 accatccctc cggtaacagg gctgcaagac gggctttttc tgccatcagc gccatgaatg
     6661 cggcaccttc cttccccgat ggcgcatcgc tggtcagcgc ataatgctca cattccagac
     6721 gaatttttgc gggattgctg tacgccccgc taccaaacac attcaggcag agcgtccatg
     6781 ccagcagtgc cagagatttg tccggctgtt gcataagcgc cgcctagact gccagcgtgc
     6841 gctctgagga cattttcgtc agcagtggca gactgatttc ctccactgac gctttctcct
     6901 gcacctgttc cgtgcggtca ccatcgtcag ccgcatcatc ctcactgcgc aactgcacac
     6961 cacgctggac acacacatta ccgtaacgcc aggacaccac cacaccgctt ccggcacgca
     7021 tctccggcgt ccacgctctg accttcgcta tgcagcgcat cagcttcatt tctgcttcca
     7081 gcaggtcgga ttcctcacac tggttttcca gcgcgtcgta acgtgccatc agttcgttca
     7141 ggcattcttc ttccgcctcc gtcagcacct cttccggctc cggcagactg cggtatgccc
     7201 gggcatcttc acggcactca ccgacaggtt ccatgcgtcc ggcgcaccat ccccagcctt
     7261 cggcttcccg aaggaactct gcgacggcct ggagtttttc cagcagggcg gcatcgagcg
     7321 caacacagtc cacatagcca ccctcgtcgt cgctgaacaa atcggtgcgc agttcatctg
     7381 gcgagaaggc atcagccccc acgaagtgga atttaccgtt ccccgccacc gccacttcac
     7441 tttcggtcac cagacgacga atggtctgta cttccggttt tcctccccat cccgactgac
     7501 aggcagcttc aaacacctgc acctgacgcg cggtgtcgtt ctccagcgcc agcgcctgac
     7561 agtgttcggt ggtgatgcgg tcttctgcca gcgcatcgag gatgacaggc gcaaggtctg
     7621 ccagtttcag cattcgctga acgtggcggg gcgaataacc cagcaaatca ccgatttgtg
     7681 caggtgtttt gccttcctgc gccattgcgc ggaagccggc aatctgttcg gcagggtgca
     7741 tatcccgacg atgaccgttt tcagtcattg atgcggctgt cgccagctcc tgcggaataa
     7801 ttttcacacg gacaggccag tcagccggaa tgatgtcacg ctctgccagc atgttgagtg
     7861 ctgccagtcg gcgaccacct gcggcgacac cgtaacggtc acctggcagg gcatgaacaa
     7921 ccagattctg taacaggccg acacctttaa tggagtccgc cagttcgctg acggactccg
     7981 caaaatacgg caccgtgcgc acattcagcg gtgacttaat cagcgaggcc agcggcacgc
     8041 tcacttcctc cgtctgcgcc agcagggtag acaggactgt ttcctgcgtt tttgcaggtt
     8101 tacggctgga tttacgctcc gtttttgcct tagactctgt aactgacata gttagtacct
     8161 cccaaaacgg taataatgat tgtctgccgg acgtgtcccc gtccggcacc tctcttactt
     8221 aagaatcccg aaatccctga tgacatggtt catccagtac ccggcaccgt cctcaaaatt
     8281 ccaggtacgc cagaccattg caccgttatt acggacaacc aggcgaaact gttcgccgtg
     8341 gtcatcctcg ataaagacgt tccggtactg tgcggcaaca gcttcggcat gtttgcgggt
     8401 aaaaggaccg tcaggcagcc cctgaagtat tctgaaatat tcgctcattc tcatctctcc
     8461 ggtgatgccc cgcacagaac ggggcggggc ggttatcaca gtcagcccga tcagaacggg
     8521 atatcgtctg aaaacccgta atcctccccc tccggcggtt gcggctgagg ctgaccgctg
     8581 aactgttgcc cctcttccgg ctgagtctga gcacctgcga cacgtcccag catctgcatg
     8641 gtgcctgtgg tcttaacaag aatttcggtg acgtaacggg tgataccgtt atcttcccag
     8701 ctacgggtgc gaagctgacc ttcgatgtag acctgcgcgc ccttgcgcag atattcgcca
     8761 gccacttccg cgagcttgcc gaacagcacc acgcgatgcc attctgtctg ctcccgcatc
     8821 tcccctgtct gtttgtcacg ccaggtttcc gacgtggcga cctgcaggtt tgccactgcg
     8881 cccccgttgg ggatgtaacg gacttccgga tcttttccca ggcgtcctac gagaatgacc
     8941 ttgttaatgc cacgaactgc catgatgtgc ctccttctgt tgatgttttc agcccccatc
     9001 atcttttgag tttcgggagc cgcggttttg acgttttgcg gggacctgcc ttttgttccc
     9061 tccggtattc accatcacct ttttgagaac cttcgccgca aggggcatca ctgccacgga
     9121 cggaaacgac tgtccggggg cagaccgcaa aagtttttgc ctgcttttgg gcaaaaactt
     9181 ttgcgggatg tacatttcac ccctggactg gcggagacgg ttgtggctgt ctttgccccc
     9241 ggcgacaggg gcttaaacag gtgaatggca ccggacagaa caacgggcag ggacccgccg
     9301 caacgacgtg aagcgcggtt tgcgaaacgg cgttgcccct tacatcccgg cggccttttg
     9361 ccgggatgcc aggagcgcag gccacggcgc gacagaggcg gcgcgaccgg aacggtcgct
     9421 gcaagcccgg ggttttcacg catcggaccg tagcgacagc ccgaaaccgc gccagcgggt
     9481 tcggcggaga ctggcaggtg cgccagcagc tgcctgtcgg agtcgggcct gacgaccgga
     9541 tgccgccagg cagccgggag ccgaaggtgc gcccggcaga caggacaaca ctgcagtagt
     9601 cagaatcaga gcagcaggaa aaagaagaac agtagcagta gcagtagcag tagcagtagc
     9661 aggaacaaca acatcatcag taacagacaa atgacaggca tgaagaaaca gaagccccca
     9721 tcagaacgtc cgcgtaatga aaggggcggc gcgtgagcgc ggcccctttc agcgccaccg
     9781 gcgcgcgttt tttcccggcg cgggctgaca ggcatttatc ctcccgccgg ccctgtgtca
     9841 tcaggcacgc agacgaataa tcatcgtcgg gacatcggta taagcaaacg tgccgcgcgg
     9901 cagctcctcg cggacgtcag aaaacggtaa cagcttctcc tgctggcgtg gtccgttgag
     9961 acagacggcg accagcactc cacccggacg caacagggaa aaggcccgca ggatatgccg
    10021 gatatcctgc ccgtggctga acggcggatt catgataacc cggctgtaat actgcactgg
    10081 ctgccattcc atgaagtcgc cacactgaac cctgacaccg ttaaaatttt cccgcagata
    10141 ccggaccagc ccgctgttga tttccaccgc atcacacatg gcccccggcg cggtatcccg
    10201 aatcgcccgc agtatggccc cggtgccggc agagggttcc agaatgtgat cacggttgct
    10261 gatctccgcc agcatcacca ggcgatcaca gaccggggca ggagtcacaa aaagctgaga
    10321 ttcagcccgg atttcagcaa ccggcgcggc gttatccagc cttgcgcgca tcagccggat
    10381 acgttctctt aactgactgt gcatatcatt atctccgtca tcccccgggg attttcccgg
    10441 ggggatatac cttatttctg tgggatttcc gtgattttca tgtcggtgat atacacattc
    10501 accaggcgga aattattgtc cattgtgcgg cggtaccggt atgccccgtg gtcttctgct
    10561 tctgccacac tgcgcacggc cttacagtcc cggggcaggg cggcccactg tgcctttgtc
    10621 atttcccgga aaccttcccc cggatagttg actaccggcg gacgcttcgc ggcctgacta
    10681 gcgacggcag cctcttctgc cgatggtgct ttgtagtccg tgatgcgatc gggcgtcact
    10741 ttcatcgtgc cgctgtaccc gagaaaactg taatttggcg ttgtgactga actcaccgcc
    10801 ccgttgcttt tgttcacacg gatgatggtc agccactcgc cccggctgaa aacctgtccg
    10861 cccggctcaa aatcctgtgt ccgggtaacc acgccgccgc tttcgtccag catggcacgc
    10921 tcatagatca ggcggttctg atagtggtta acccagcgtt gttgatgctg aatctgccgt
    10981 tcatgacagc ggatcgcaat ttcgcgggcc tgctccgtgg tgatgatgtc atcatccagg
    11041 gccgaccata acgatcgact tccttcatac tggctttttt ctgccgggcg cggatacgta
    11101 tccagcggga aacaggcgct gatatggtca tgactgctga tgagttttgc catattcaga
    11161 tccagcgatt cagcccgcca catcgtcaga tatttctgcg actgcgcgat ggtcttttca
    11221 gccttgcgca aatcagcttc gatttttttg atacgacgcc agcgaacgtc cggacgttct
    11281 ttatacttcg cgtgaagcag tgccgaccgc gcccgctctt cccagtattc cgcacgttca
    11341 aagagcatca cggctcgttt catgccgttt tcaatacgct gcgcatcacg acgggcgcgg
    11401 cgttcgctgt gatgccccac aagaatgggc tgaccgggcg ggatcatcgc ggccagtctt
    11461 tccacttcat caagtgcctg tgcggattca ctggcccgct ttccgctgta tccggtaaac
    11521 cgctccgccc gtgcttcctg acgttcagcg agcgtgctgt cttcatcctc aatctctccg
    11581 gcaagtgaga ggagcacgtc ttcccggccc ggtgtccatg ctggcgcgac aaacagcgcc
    11641 tgttttggtg cccagcggaa accggcatca tgcacttttt tatacgtctc cgagtcaaga
    11701 cgtgacacgg catacaggcg cagtttgttg tcatccggtg agtaggtcgc gcggtacatc
    11761 tgcacagggc tggcggcttc cggggcggtc atggtgattg ctgctaatgt cataaaatgt
    11821 tctccttccg tctgttgccg cccctcgcgg ggcggctcac ctcatcagtt aaaagcgcgt
    11881 ttcagttcga gtgtgcggag cacctgcccg aaggccgtgt ttttcatggc ggggatgtgt
    11941 acaccacgcc cccggtgaaa actccgggca atgtgtcgcc cgaaggcttt cagcacgggg
    12001 tcaatttccg gcgcggggat gtcttcgcgt ctgaaacggg gatgacggcg gggctttaca
    12061 gccgctgcgg aaggtgaaac aatacttact gtcataattt agcctcttat gacgttaatt
    12121 aatgaaaccg taaagactgt tcgtgcagtc tctgcggtgt ggattaagca ggtccctgac
    12181 ctgctttttt catatctgcg tctgacgttc tccggtgttt tcctccttct gttcctgcgt
    12241 tctcattacc tgccagccgg atgactgaca gaacacataa atgcgtattg ccggagcctg
    12301 aaataaatcc tgatttttaa agaacatcac ccgttgagtt tcgggagccg cggttttgac
    12361 gtttcgcggg aacctgctgc tgtattccct gtggtatgaa cttcacccgt ttgagaacct
    12421 tcgccgcaag gggcatcact gccacggcct gacgcacctg tcctgggcag aacgcaaaat
    12481 tttttaccgg gttttgggta aaaaattttg tgggctgttc atttaccctg gacagtcagt
    12541 gcggcaggtt gtggctgtat cagcccccgg cgacagggac tcatacgggt gtgtagcacc
    12601 ggcaggcaat gagcagggac ccgccgcaac gacggagagc gcgtgcgcga aacggcgttg
    12661 ccccttacat cccggcggcc ttttgccggg atgtcgggag cgcaggccac ggcgcgacag
    12721 aggcggcgcg accggaacgg tcgctgcaag cccggggttt tcacgcatcg gaccgtagcg
    12781 acagcccgaa accgcgccag cgggttcggc ggagactggc gggtgcgcca gcagctgcct
    12841 gtcggagtcg ggcctgacga ccggatgccg ccaggcagcc gggagccgaa ggtgcgcccg
    12901 gcagacagaa caacactgca gtagtcagaa tcagagcagc agataaagga acaacaacat
    12961 caggaacagt tccataacat aagaaagaaa cactcctgag tcagacacat cacagacggg
    13021 aagggtaacg ggcgacgcgt cagcgtggcc cgcttccctt ccggcaggcg tcagcctgcc
    13081 aggggttttc gcgcggactg acaggcggcc tccaccgcct gcccctgtat cacctgtttc
    13141 tgctaccctg taagatgtag tgaccgccca ggaaaaccgc ctgctgattc accacaaaat
    13201 cgcagatttc atcaacaatc tgcgcggtgg tgagcggttt ctgccccatt tcacgacgcc
    13261 gcgcattaat cacggccctg taattacgca gaatttcgcg ggtttctgtg ctgatattca
    13321 tgacatcgtc tccccgtcca gcgcctttaa cacaacgtcc attgcttcgc gttcctccct
    13381 gacgaatgcg tcaccgtcgc ccccgttctc actcccgacg gcatacaggc gcttcatttc
    13441 actgcctgcc agcgccatca ctttttccag catcaccgcc gggactgtca cctgacggct
    13501 ggcgcgcttt tcttccatca gttcacgaac aacgccgtga acaacgctga catccgcacc
    13561 atattcaaag gcatcgtcca gccgctgcat gacggtttcc agctcatcgt ctgtcagact
    13621 ccagtcctgg gctatgtgac gcacatcccc acgggtcagc actacggcaa aaacgcattc
    13681 actgtccggc acgtctgtat ccagcacttc gcggataatt tctttaacag tacagtacat
    13741 gttctcgtct cctttacagg ggcggcattg ccgccccgtc cgttaatcag tccagagccg
    13801 cgtaaatcgc gttgcattcg aggtgaaatt cgatgtgacg ccacaactgc gcatcgcgca
    13861 tccggtaaag ctgggtcagt cctgcatccc cgctgtcgtg gtacagccac aactggcggt
    13921 taatcacaag ggaggtcagg atgatgcctg cggcatcagc actcacggta cggtcaaacc
    13981 agtttgcacc gttcaccatg tggaaacggt cgccatccgg catcatgtaa ccgccaccgt
    14041 ccggcaggcg gatgaagtgc cagaagcctc cctgatattc cggcatcatt ttttgcgcca
    14101 gcgcgtacac atacgcctcg gcatacagaa aatcgttgcc aaacagatac ggcagaaagg
    14161 agagacggtc gcactcttca acattcagag tgacaggttt cgcatattgc atgatgtttt
    14221 cctccgttgt tcacatattc tgcgacaccg ggcggtgccg tgcctccata aaagccgggc
    14281 gaacaggcgg ggatgcaggg gcgcaaggga agccgcagcc tgacgcacac ggctgacggg
    14341 agttgcaggg tgagaccgcg aaatctgagc gggtgaacga ccggaaaatc acggcagacg
    14401 ggaaggaggg accgggtgac cgcagcggcg aagcgtaccc ttgcatcaac gccagcccgg
    14461 ctaagatgga ggcacggcac agcccgcaca cgacgctgag gccacataac tgaaaaacca
    14521 caaggccatg ccctgcatgg ccgggtaaag cggagccggc ggcgacttcc tttgtgctct
    14581 gtccggggac cggcaggaaa aaggcgggga tttaccctgc caacgtcatc atttccggat
    14641 ttttgccagg gcatccgcca tgctgcggat ttcggcccgg gctttccgga ccacctcccg
    14701 cagaacacca cggtcaaacc agcggcgggg cggttcatcc ggtatacgca gcacatcgca
    14761 ggccagccca ctggacagga tatgctcaat acaatcgctg accaggtaca tttccaccga
    14821 cgaaaaacgt gctccccggt tcacgatggc atcgagcacc acgggcaggt tttcgtcatc
    14881 ttcatcgagc cagcaggggt gatcgctttc cttcacaacc agacgaaagc ggcgcgtctg
    14941 gcgggtcagc aacgtctgac cggtggtggt cagcgccgcc cggatacgcc gcgcatcgtc
    15001 tgccacctgg taacagatgc ttcgtattgc atcgcgcacc gccgcaagta cagccctgat
    15061 ttcgtcttct gccagccact caccggcata cgggaaagac acctgcgttc cgtctgccgg
    15121 aagtaccggc agcgactgcc actgactgcc ggacagaaca agttccgccc cggttccggt
    15181 cagtttctga atggcagagg ccaggtgcgg cggcagtacg ccgccgtgac ggttgataag
    15241 taacgtcgcc agccggggcg catccagccg cacgtaaatg ctgatccagc ccggatggtt
    15301 cggatttcgc tggtcaacat ccgtctcttc cggccagccc tgcgccagca gcaggttacg
    15361 ggcgtggcga caaatcagtg cattcagcgt ttcgttcatg attcatggtc tccctgaatc
    15421 gccgcccgca ggcggcgata acatcagtcg ttttcgcgtg tgttgttttt cagcagggtg
    15481 cgggcctgat taatcaccgc ctgacggcgg gtgacgcatt ccgggacggc gaggccatga
    15541 tcccgggcgg cccattcacg tttccacaat gcctgttcag cggtctgaat cagggacgcc
    15601 agcagttcag cagggacggt cacctggcgg ttttcgctca cgttattgat gatctccatc
    15661 gccacgccgg aagaaatacc ggattcagtc cgctggtctt ccgggatgtc ctccaggcgc
    15721 gccaggacgg ttctgatttc atgatcggac agggaaatat ccattccgtc agcgagggcc
    15781 tgaatctctt ccggggacca gataaccagc atcagcggca tgtctcccgg atactttact
    15841 gccagctccc ggcatagcgt ttcgcatgtt ccgtacattc tcgtctcctt ctcaatcttt
    15901 aaagcacgca tccagttcca gaatttcggt atatgcctcc atcaggaggc ggtttgcgcg
    15961 aaacagcgtc tgacgcacca gacgttccgg cagggtgtcg gcattaaagc tgtaccgctg
    16021 ctccatctca ttcatggttg tacgcaggtc gcacatggca ttggccacct ccgccacttc
    16081 ggcgcgcagt ttttcgtgtc cggcatagtt catttacgca gcctccggca taaaccagtc
    16141 atcattcgcg gccccctgct gcatggcccg ttgcacggcg gcaaggcgtt gctgcccggc
    16201 acggtgatac tgctcaagca gctcgatacc gatataccgg cgtccggact ggagggcggc
    16261 gacgcaggtt gagccgctgc ctgcaaacgg gtccagcaca attgcgttcg ggtgtgtgaa
    16321 gctctcaatc agcggttgca ggctggtaac gggcttttcc gtcgggtgat gacgattgcc
    16381 cgaatatttc cagcccagca cgtccggcag cgggtttggt ggcagacgtg gacggccttt
    16441 tgccaggatg taggcgcatt cgtggcgata gcccacatat gcggccttcg atgtgtagtt
    16501 tttggtgaag accaggtgac caacaacgct gaatcccgca tttttccagg cggccataaa
    16561 gcgatcgacg cggttccagc cgtagaagct gaccatcagc gcatcttttt tgagtacgcg
    16621 aaacatttca atacaggccg gttgcagcca ttcatcggtt ttatcgccgg caatggtacg
    16681 cccggaacgg tcacggaaac cgacgagata cggcgggtcg gtgaggatga aatcgacagc
    16741 attgtccgga aacgtggcca taactcgcac gcagtcaccc aggataaaac gggacataaa
    16801 agcctccttc tcttacagaa ggcaccggga gggcacccct gtggtgcccg ttccccgcgg
    16861 cctgtgggct gttcaccgcg tccggtaacg ggtcaggccg accgtggaat accgcagccg
    16921 tcgtcttttt gacggcaagg ctatgccgcg aaagcggctt gaagggcgtt catcagaaaa
    16981 gggcgacggg ctggcgtaca ctgtcaccgg tgccagccgg gagcggtaaa agcgcccgtc
    17041 ccgtgcccgc cggacgcggg acactgacca caggcagcgt ttatgccgcg ccgcgtcagc
    17101 cggcgcagta aaaagaggag cacggcgaca tcctttgtcg gaaaagaaac gggcggttgc
    17161 ccgcccgtct ccgtcagaat tcatccaccg taatgcgcca ccttgtcgac aatccacgca
    17221 ggtccggtga cttccggcag ctcatcgtca tctgtcgggg aagaccattc cagttccccc
    17281 cacaggacat caacaagctc tccacgctca tatcgctgcc agccacagaa attgcagccc
    17341 tgctcggcat accagtgctc cagtgtgcaa ctgaaacggc ggcttaattc tgcaataacg
    17401 tcgctttccg gctgacacca cggcgtgtcg aaatcaacct gaatgaagtt gtctccctga
    17461 ctgctgatat tcacctcata ccccacaggc cacttcacgc catactgttc cgtataccag
    17521 tgatacgcag aaggaacacc gttcagaaca ccaccgttaa agccattcac ttcaacatcc
    17581 aggcgggtgg gcagaaccgt cagcaggtca aacggcatgg ttttttccgg cagtacattg
    17641 tcacacagac ggttccacca caccgataca tcctcgttac tccagaagcc acaccagtca
    17701 cctcttttgg cggtgaaatg cacggtgatg gtttccctga cctcatccgg taatccttcc
    17761 cagcgacgct ggccagtacc actctgcagc cagagttcat gcagcatcag gcagttttgt
    17821 tcatccagta gcacaccgtt ctgcaggtgt gtcagccagc gggtgaacgc gatattctcc
    17881 ggcgatacaa caccacgccc ggcagccgtc agtccggggc atggttcaaa ccgcacatct
    17941 tcagtggtct gcagaagtcc ggcactaccg gccagaaaca gctgaatacc ttcatctgtg
    18001 gcgcggcgat aaagcggtgt gactgcaccg ctggccagtc gtttaatctc agcgatctgt
    18061 gctggttcac cagaaaaatg catacgattt gagcaccagt ttggcatggg aattctcctc
    18121 tcacatgcgg cctccatcag gccgtgccgc acctgtaacc gggcgaccgc atacgaatgc
    18181 aggtgcggcc ccgaagccgc agcgcgtgga ggaggaacga cgaaacgtga ccgggtgagg
    18241 aggccggcga cagcgacaca cttgcatcgg atgcagcccg gttaacgtgc cggcacggcc
    18301 tgggtaacca ggtattttgt ccacataacc gtgcgcaaaa tgttgtggat aagcaggaca
    18361 cagcagcaat ccacagcagg catacaaccg cacaccgagg ttactccgtt ctacaggtta
    18421 cgacgacatg tcaatacttg cccttgacag gcattgatgg aatcgtagtc tcacgctgat
    18481 agtctgatcg acaatacaag tgggaccgtg gtcccagacc gataatcaga ccgacaacac
    18541 gagtgggatc gtggtcccag actaataatc agaccgacga tacgagtggg accgtggtcc
    18601 cagactaata atcagaccga cgatacgagt gggaccatgg tcccagacta ataatcagac
    18661 cgacgatacg agtgggaccg tggtcccaga ctaataatca gaccgacgat acaagtggaa
    18721 cagtgggccc agagagaata ttcaggccag ttatgctttc tggcctgtaa caaaggacat
    18781 taagtaaaga cagataaacg tagactaaaa cgtggtcgca tcagggtgct ggcttttcaa
    18841 gttccttaag aatggcctca attttctcta tacactcagt tggaacacga gacctgtcca
    18901 ggttaagcac cattttatcg cccttataca atactgtcgc tccaggagca aactgatgtc
    18961 gtgagcttaa actagttctt gatgcagatg acgttttaag cacagaagtt aaaagagtga
    19021 taacttcttc agcttcaaat atcaccccag cttttttctg ctcatgaagg ttagatgcct
    19081 gctgcttaag taattcctct ttatctgtaa aggctttttg aagtgcatca cctgaccggg
    19141 cagatagttc accggggtga gaaaaaagag caacaactga tttaggcaat ttggctgtgt
    19201 tgatacagcg ggtaataatc ttacgtgaaa tattttccgc atcagccagc gcagaaatat
    19261 ttccagcaaa ttcattctgc aatcggcttg cataacgctg accacgttca taagcacttg
    19321 ttgggcgata atcgttaccc aatctggata atgcagccat ctgctcatca tccagctcgc
    19381 caaccagaac acgataatca ctttcggtaa gtgcagcagc tttacgacgg cgactcccat
    19441 cggcaatttc tatgacacca gatactcttc gaccgaacgc cggtgtctgt tgaccagtca
    19501 gtagaaaaga agggatgaga tcatccagtg cgtcctcagt aagcagctcc tggtcacgtt
    19561 cattacctga ccatacccga gaggtcttct caacactatc accccggagc acttcaagag
    19621 taaacttcac atcccgacca catacaggca aagtaatggc attaccgcga gccattactc
    19681 ctacgcgcgc aattaacgaa tccaccatcg gggcagctgg tgtcgataac gaagtatctt
    19741 caaccggttg agtattgagc gtatgttttg gaataacagg cgcacgcttc attatctaat
    19801 ctcccagcgt ggtttaatca gacgatcgaa aatttcattg cagacaggtt cccaaataga
    19861 aagagcattt ctccaggcac cagttgaaga gcgttgatca atggcctgtt caaaaacagt
    19921 tctcatccgg atctgacctt taccaacttc atccgtttca cgtacaacat tttttagaac
    19981 catgcttccc caggcatccc gaatttgctc ctccatccac ggggactgag agccattact
    20041 attgctgtat ttggtaagca aaatacgtac atcaggctcg aaccctttaa gatcaacgtt
    20101 cttgagcaga tcacgaagca tatcgaaaaa ctgcagtgcg gaggtgtagt caaacaactc
    20161 agcaggcgtg ggaacaatca gcacatcagc agcacatacg acattaatcg tgccgatacc
    20221 caggttaggc gcgctgtcaa taactatgac atcatagtca tgagcaacag tttcaatggc
    20281 cagtcggagc atcaggtgtg gatcggtggg cagtttacct tcatcaaatt tgcccattaa
    20341 ctcagtttca atacggtgca gagccagaca ggaaggaata atgtcaagcc ccggccagca
    20401 agtgggcttt attgcataag tgacatcgtc cttttcccca agatagaaag gcaggagagt
    20461 gtcttctgca tgaatatgaa gatctggtac ccatccgtga tacattgagg ctgttccctg
    20521 ggggtcgtta ccttccacga gcaaaacacg tagccccttc agagccagat cctgagcaag
    20581 atgaacagaa actgaggttt tgtaaacgcc acctttatgg gcagcaaccc cgatcaccgg
    20641 tggaaatacg tcttcagcac gtcgcaatcg cgtaccaaac acatcacgca tatgattaat
    20701 ttgttcaatt gtataaccaa cacgttgctc aacccgtcct cgaatttcca tatccgggtg
    20761 cggtagtcgc cctgctttct cggcatctct gatagcctga gaagaaaccc caactaaatc
    20821 cgctgcttca cctattctcc agcgccgggt tattttcctc gcttccgggc tgtcatcatt
    20881 aaactgtgca atggcgatag ccttcgtcat ttcatgacca gcgtttatgc actggttaag
    20941 tgtttccatg agtttcattc tgaacatcct ttaatcattg ctttgcgttt ttttattaaa
    21001 tcttgcaatt tactgcaaag caacaacaaa atcgcaaagt catcaaaaaa ccgcaaagtt
    21061 gtttaaaata agagcaacac tacaaaagga gataagaaga gcacatacct cagtcactta
    21121 ttatcactag cgctcgccgc agccgtgtaa ccgagcatag cgagcgaact ggcgaggaag
    21181 caaagaagaa ctgttctgtc agatagctct tacgctcagc gcaagaagaa atatccaccg
    21241 tgggaaaaac tccaggtaga ggtacacacg cggatagcca attcagagta ataaactgtg
    21301 ataatcaacc ctcatcaatg atgacgaact aacccccgat atcaggtcac atgacgaagg
    21361 gaaagagaag gaaatcaact gtgacaaact gccctcaaat ttggcttcct taaaaattac
    21421 agttcaaaaa gtatgagaaa atccatgcag gctgaaggaa acagcaaaac tgtgacaaat
    21481 taccctcagt aggtcagaat aaatgtgacg aaccaccctc aaatctgtga cagataaccc
    21541 tcagactatc ctgtcgtcat ggaagtgata tcgcggaagg aaaatacgat atgagtcgtc
    21601 tggcggcctt tctttttctc aatgtatgag aggcgcattg gagttctgct gttgatctca
    21661 ttaacacaga cctgcaggaa gcggcggcgg aagtcaggca tacgctggta actttgaggc
    21721 agctggtaac gctctatgat ccagtcgatt ttcagagaga cgatgcctga gccatccggc
    21781 ttacgatact gacacaggga ttcgtataaa cgcatggcat acggattggt gatttctttt
    21841 gtttcactaa gccgaaactg cgtaaaccgg ttctgtaacc cgataaagaa gggaatgaga
    21901 tatgggttga tatgtacact gtaaagccct ctggatggac tgtgcgcacg tttgataaac
    21961 cagggaaaag attcatagcc tttttcatcg ccggcatcct cttcagggcg ataaaaaacc
    22021 acttccttcc ccgcgaaact cttcaatgcc tgccgtatat ccttactggc ttccgcagag
    22081 gtcaatccga atatttcagc atatttagca acatggatct cgcagatacc gtcatgttcc
    22141 tgtagggtgc catcagattt tctgatctgg tcaacgaaca gatacagcat acgtttttga
    22201 tcccgggaga gactatatgc cgcctcagtg aggtcgtttg actggacgat tcgcgggcta
    22261 tttttacgtt tcttgtgatt gataaccgct gtttccgcca tgacagatcc atgtgaagtg
    22321 tgacaagttt ttagattgtc acactaaata aaaaagagtc aataagcagg gataactttg
    22381 tgaaaaaaca gcttcttctg agggcaattt gtcacagggt taagggcaat ttgtcacaac
    22441 accttctcta gaaccagcat ggataaaggc ctacaaggcg ctctaaaaaa gaagatctaa
    22501 aaactataaa aaaaataatt ataaaaatat ccccgtggat aagtggataa ccccaaggga
    22561 agttttttca ggcatcgtgt gtaagcagaa tatataagtg ctgttccctg gtgcttcctc
    22621 gctcactcga gggcttcgcc ctgtcgctcg actgcggcga gcactactgg ctgtaaaagg
    22681 acagaccaaa catcatggtt ctgtgttcat taggttgttc tgtccattgc tgacataatc
    22741 cgctccactt caacgtaaca ccgcacgaag atttctattg ttcctgaagg catattcaaa
    22801 tcgttttcgt taccgcttgc aggcatcatg acagaacact acttcctata aacgctacac
    22861 aggctcctga gattaataat gcggatctct acgataatgg gagattttcc cgactgtctc
    22921 gttcgcttct cagtggataa cagccagctt ctctgtttaa cagacaaaaa cagcatatcc
    22981 actcagttcc acatttccat ataaaggcca aggcatttat tctcaggata attgtttcag
    23041 catcgcaacc gcatcagact ccggcatcgc aaactgcacc cggtgccggg cagccacatc
    23101 cagcgcaaaa accttcgtgt agacttccgt tgaactgatg gacttatgtc ccatcaggct
    23161 ttgcagaact ttcagcggta taccggcata cagcatgtgc atcgcatagg aatggcggaa
    23221 cgtatgtggt gtgaccggaa cagagaacgt cacaccgtca gcagcagcgg cggcaaccgc
    23281 ctccccaatc caggtcctga ccgttctgtc cgtcacttcc cagatccgcg ctttctctgt
    23341 ccttcctgtg cgacggttac gccgctccat gggtattttc agtgttgcca ccatcgtctg
    23401 cagctggctg acgtaccagg agtcagagag cggaaccagc cggtgagtct gctgaccggc
    23461 gggcattctc cccgccgtcc tggcagcttt ttcggtccgt tgtttcaggg tcgcaagctg
    23521 cacaaacgga tacggaggcg tgagcgaaaa atccccccgc gtcagcgcta gtgcttcatt
    23581 aatacgcgcg ccggtgttcc acagagtggc cagcagcatc ttgcggcgca gatccgggac
    23641 ataatgaagc agggcactca cctcgggagc cagcagatat ttcggcagtt catcatgaac
    23701 catcgacatc tggcggagtg ccagagctgc cggataatca atggcaacag gaagttgtgc
    23761 agactgtccg gcagaataca ctgccggtac catggctgca gactggctgt gtataacgga
    23821 gcctgacatt tatattcccc agaacatcag gttaatggca tttttgatgt cattttctcg
    23881 gtggctgaga tcagccactt cctccccgat aacggagacc ggcacactgg ccatatcggt
    23941 ggtcatcatg cgccagcttt catccccgac atgcaccacc gggtaaagct cacgggagac
    24001 cttatctgac aacagacgtg cactggccag ggggatcacc atccgtcgcc caggcgtgtc
    24061 aataatgtca ctctggacat ccacaaacag acgataacgg ctctctcttt tataggtgta
    24121 aaccttaaac tgcatttcac cagtccctgt tctcgtcggc aaaagagccg ttcatttcaa
    24181 taaaccgggc gacctcagcc atcccttcct gattttctgc ctgccagcgt tcggcacgca
    24241 gacgacgggc ttcattctgc agggtggtgc ttaccagccc ggagatattg acatcatatg
    24301 ccttgagcaa ctgatagctg tcactgtcga cggtgactgt aatgcgctgc ttcataatgc
    24361 acctcatctt acatactctc tgtacaccat taagtataca ccagtattac gctataacat
    24421 gcctccggca acggaatatt gttatccagc tattattaac accaccatca ataactgacc
    24481 tgaaaagtaa tcatgacaat aataacctgc aatgtagtaa ccatgataaa ttacaggatg
    24541 actgtttttc tatgatccga tttttatcgg attcaggatt ttccggaagt gaatcaggat
    24601 cagtgaataa gcgaagcgat cttttctgcc gctgatgact ggctcgggaa cacgggaaga
    24661 aacacaacat acagtgtcat gtcagcggag cgggacacca catcctgtga aagcggacca
    24721 gcgggcggca gcgaaggatc cgcggatccg gaaccaccag aaaccggatc tgcacgggga
    24781 aagagagaaa ataacatagg ctgaacatat ccatatgcct gacatctgca tattcatggt
    24841 atacgcatat cctcaccatc tgcatatgct gaatctatac atatgcctaa catctgccta
    24901 tactaaacat atgcacacac ccggtgcaat gaacatcatt ccggatatgc atcacatatc
    24961 cacacttacc cgggagagaa tcatgagaac cgtatccatt tttaaaaatg gcaacaaccg
    25021 tgctatccgc cttccacgcg atctggattt tgagggggtg agcgagctgg agatcgtccg
    25081 ggaaggggac agcatcattc tgcgccccgt ccggccgacc tggggctcat tcctggagct
    25141 agaaaaggcc gatccggact ttatgacgga gcgcgaggac gttgtcagcg acgaaggacg
    25201 agttaacctg tgaacaagat ctatatgctc gacacgaaca tctgctcgtt catcatgcgc
    25261 gagcaacctg aagcattgct taagcacctg gagcagtcgg tgctgcgcgg tcaccgtatc
    25321 gtggtctcgg ccatcaccta ctccgagatg cgcttcggtg ccaccggtcc gaaggcctcg
    25381 ccacgccacg tgcaactggt tgacgcgttc tgtgagaggc tcgatgccgt cctgccgtgg
    25441 gaccgcgccg cggtggatgc gaccacggag attaaggtgg cactgcgtct cgccggcacg
    25501 ccgatcggtc cgaacgacac ggcgatagcc ggacacgcca tcgctgcctg tgccattctg
    25561 gtgacgaata atgtgagaga gtttgagcgg gtaccgggtc ttgtgctgga agactgggta
    25621 agataacgct gtaaaacaaa acaggcggtc aggcgcggcc ggccgctctt tcaggcagcg
    25681 gtatataaag gaataaaaaa atgccactga tcacgcggct tatgctgcaa aacttcaaaa
    25741 agtttccgga actggacctg cgcttcagca acgatcgtaa cattctggtt ggggacaatg
    25801 agtccgggaa aagcactatt ctgctggctc ttgaccttgt gctgagtgac agcaggcatc
    25861 gggttgaggc gctgggggtg gaatcgctcc tgtcacagtc agcagtcagg cattttcagg
    25921 aaggtgagcg ccgtgccgat cagttacccg tgctgaccgc tgacgttttc ctgagtaatg
    25981 ggggagagcc tgacctgaac ggcaggcaaa atctggcggg tatcgatgcg gatggtctca
    26041 gaatgcgcat tgctcccatg atggaggaat acggtcagga tatacaccat gttttgcagc
    26101 aggatcctga taattttccc tatgaatact attccgtgca gttcagcaca ttctccggtg
    26161 gtcatttcgc aggcttcaga cgctatctgc gccatctgtt cttagacagt gcacgcattg
    26221 ataacgagca tgccgcacag gagtatacgc gcacagttta cagcgtcaat gtgccggtgg
    26281 ccgatcggta ccggcttgaa aacagttacc ggcaacagaa aatgcacttc tgcgcccggc
    26341 atctgtccgc cataaacgac acgctgaaaa cgtatcagtt tggcgtgcgt tccggcgcta
    26401 aatcaggtct tgaggcgaac ctggacatta ctgaggacgg tatttccatt cgtcaccgcg
    26461 gaaaaggaag acagtgtttc atcaaaacgg agtttgcgct gcagcggcat cagcagcagg
    26521 ggggagagat ccacgcgctg ttgcttgagg agccggagaa tcatctcagc catgtcagta
    26581 tgaagaggct ggttaatcag cttgccacgg aacggcagac gcaggtgttt attgccacac
    26641 acagtagcca tatctcctcc cgcctcgacc tacgtaaggc tattctcctc ggagctaccc
    26701 ggccggtact gatgaatgaa ctttccgctg agactgccgc cttcttcatg aaagcaccgg
    26761 ataataacgt gctggaattt gcgctggcca gacgcgtgct gctcgtggag ggggatgctg
    26821 agtttattct gatcgaggcc ttttatcacc gcctgtatgg cagggcaccg gaggatgacg
    26881 gggttcacat catcgctatc ggcggaacga gtttccgtcg ttatcttgaa ctggcccgtc
    26941 ttctggaaaa tcgtgtcgcg gcccttcgcg acaatgacgg caactatcag caaaattgcg
    27001 atgaacgcta tgctgacgtg ctttgttccc gctcccgggt atttgctgac cacgacaaca
    27061 gccgctccac atttgaaatc tgcctgtatc aggataatgc cgacctgtgt gatgcgcttt
    27121 tccgcggaac ccgccggaca ctcacggttc aggattacat gctggccaat aaggcagaag
    27181 cagcattcca gctgttacag ttgcacgccg aaaagctgac cgttcctgat tatatccagg
    27241 aggcactggc atggataaga gagtgatatt tgcggttgcc ggctcgggta aaaccacgct
    27301 gctgatacgt cggttaagag aggaccggcg gacgctgatc ctgaccttca ccgtaaataa
    27361 tgaagcacat ctgcgggcgc agattatcag acgctttggc tacataccgt acgggatccg
    27421 tgtgatgacc tggtttgagt ttctgcacgg tttctgtttt cgccctttcc tgcaggagca
    27481 actgtcatcg cgtggtctga gcttcaacca gcccccttcc agaataccgc gcacgaatat
    27541 ccggcattat caggatcccg ccggacggct gtatcaccgg cggctcgcac acctgctgac
    27601 agcccggggg ttgctgccag atatccgtac ccgacttgcc cgttactacg atgagttgtt
    27661 cgttgatgaa gtccaggact ttgccggcca tgactttaat tttctgctgg agctatgccg
    27721 cgcggaaatc tcagtgctgt gctgcgggga tttttatcag catacctttg acacaagccg
    27781 cgacggtaac gtcaatgcta cgctgcatga agacataacc cgatacgagg ctcgcttcag
    27841 ggctgcgggt atcatggtgg attgtgagac gctcagccgg acatggcgct gttcagctac
    27901 agtgtgtgag ttcattaccg gacaactgaa cattcgcatt tcggctcatg gaacacatac
    27961 cacccagatt gaaatcgtca cggatgaagc gcgttcagcg gccctgcacg cggacaacac
    28021 gatgatcaag ctcttctatc gcgaacatca ccgttacgga tgccactcaa tgaactgggg
    28081 gggcagtaaa ggactcgacc actttcagga cgtctgcatc gtgatggggg ccaaccactg
    28141 gatgcgcctc atccaacaga agctggcagc acttccacca tcatcccgta acaggctata
    28201 cgtggcctgc tcacgggcac ggggcaacat ctattttatt ccggaaagcc atcttcggag
    28261 attcagaaac taagtcagcg gcttctcaac tgggcacaag ccggtaaaaa gtagtcaacg
    28321 acaaaacttc aggccgaaaa atgaggctcc ggtttcgccg gaaaccggac ctgcgtggag
    28381 ggaaacccgc agatgatatg atatttatca ttaatcgcat aataaatcct ggcctgatat
    28441 ttacaggcag agaaataaat cattcgatat atgattttat cgtcatcagc cattaacccc
    28501 ccaggaagc
//
LOCUS       DAPGUL010000055        28393 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.055, whole genome shotgun sequence.
ACCESSION   DAPGUL010000055 DAPGUL010000000
VERSION     DAPGUL010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 28393)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28393)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28393
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.055"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..328)
                     /gene="tuf"
                     /locus_tag="RHX21_002554"
     CDS             complement(<1..328)
                     /gene="tuf"
                     /locus_tag="RHX21_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDV1987716.1"
                     /translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAA
                     RAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVAAT"
     gene            complement(399..2513)
                     /gene="fusA"
                     /locus_tag="RHX21_002555"
     CDS             complement(399..2513)
                     /gene="fusA"
                     /locus_tag="RHX21_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020455498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDV1987717.1"
                     /translation="MARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVH
                     DGAATMDWMEQEQERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERS
                     MRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVNQIKT
                     RLGANPVPLQLAIGAEEHFTGVVDLVKMKAINWNDADQGVTFEYEDIPADMVELANEW
                     HQNLIESAAEASEELMEKYLGGEELTEAEIKGALRQRVLNNEIILVTCGSAFKNKGVQ
                     AMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHASDDEPFSALAFKIATDPFVGNLT
                     FFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVT
                     TGDTLCDPDAPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTD
                     EESNQTIIAGMGELHLDIIVDRMKREFNVEANVGKPQVAYRETIRQKVTDVEGKHAKQ
                     SGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQLKAGPL
                     AGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPVLLEPIMKVEVETP
                     EENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMFGYATQLRSLTKGRASYTM
                     EFLKYDEAPSNVAQAVIEARGK"
     gene            complement(2610..3080)
                     /gene="rpsG"
                     /locus_tag="RHX21_002556"
     CDS             complement(2610..3080)
                     /gene="rpsG"
                     /locus_tag="RHX21_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015873274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HDV1987718.1"
                     /translation="MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVY
                     SALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMR
                     WIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMAEANKAFAHYRW"
     gene            complement(3177..3551)
                     /gene="rpsL"
                     /locus_tag="RHX21_002557"
     CDS             complement(3177..3551)
                     /gene="rpsL"
                     /locus_tag="RHX21_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005306278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HDV1987719.1"
                     /translation="MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKK
                     PNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGAL
                     DCSGVKDRKQARSKYGVKRPKA"
     gene            complement(3677..3964)
                     /gene="tusB"
                     /locus_tag="RHX21_002558"
     CDS             complement(3677..3964)
                     /gene="tusB"
                     /locus_tag="RHX21_002558"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusB"
                     /protein_id="HDV1987720.1"
                     /translation="MLHTLHRSPWLTDFAALLRLLSEGDELLLLQDGVTAAVDGNRYL
                     ESLRNAPIKVYALNEDLIARGLTGQISNDIIPIDYTDFVRLTVKHSSQMAW"
     gene            complement(3972..4331)
                     /gene="tusC"
                     /locus_tag="RHX21_002559"
     CDS             complement(3972..4331)
                     /gene="tusC"
                     /locus_tag="RHX21_002559"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusC"
                     /protein_id="HDV1987721.1"
                     /translation="MKRIAFVFSTAPHGTAAGREGLDALLATSALTDDLAVFFIADGV
                     FQLLSGQKPDAVLARDYIATFKLLGLYDIEQCWVCAASLRERGLDPQTPFVVEATPLE
                     ADALRRELANYDVILRF"
     gene            complement(4331..4717)
                     /gene="tusD"
                     /locus_tag="RHX21_002560"
     CDS             complement(4331..4717)
                     /gene="tusD"
                     /locus_tag="RHX21_002560"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusD"
                     /protein_id="HDV1987722.1"
                     /translation="MRFAIVVTGPAYGTQQASSAFQFAQALIAEGHELSSVFFYREGV
                     YNANQLTSPASDEFDLVRGWQQLNAQHGVALNICVAAALRRGIVDETEAGRLGLASSN
                     LQPGFTLSGLGALAEASLTCDRVVQF"
     gene            complement(4717..5439)
                     /locus_tag="RHX21_002561"
     CDS             complement(4717..5439)
                     /locus_tag="RHX21_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709120.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDV1987723.1"
                     /translation="MSRSLLTNETSELDLLDQRPFDQSDFDILKSYEAVVDGLAMLIG
                     SHCEIVLHSLQDLKCSAIRIANGEHTGRKIGSPITDLALRMLHDMTGADSSVSKCYFT
                     RAKSGVLMKSLTIAIRNREQRVIGLLCINMNLDVPFSQIMSTFVPPETPDVGSNVNFA
                     SSVEDLVTQTLEFTIEEVNADRNVSNNAKNRQIVLNLYEKGIFDIKDAINQVADRLNI
                     SKHTVYLYIRQFKSGDFLGQDK"
     gene            complement(5606..6418)
                     /gene="fkpA"
                     /locus_tag="RHX21_002562"
     CDS             complement(5606..6418)
                     /gene="fkpA"
                     /locus_tag="RHX21_002562"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HDV1987724.1"
                     /translation="MKSLFKVTLLATTMAVALHAPITFAAEAAKPATTADSKAAFKND
                     DQKSAYALGASLGRYMENSLKEQEKLGIKLDKDQLIAGVQDAFADKSKLSDQEIEQTL
                     QAFEARVKSSAQAKMEKDAADNEAKGKEYREKFAKEKGVKTSSTGLVYQVVEAGKGEA
                     PKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPGWTEGLKNIKKGGKIKLV
                     IPPELAYGKAGVPGIPPNSTLVFDVELLDVKPAPKADAKPEADAKAADSAKK"
     gene            6639..6857
                     /locus_tag="RHX21_002563"
     CDS             6639..6857
                     /locus_tag="RHX21_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein SlyX"
                     /protein_id="HDV1987725.1"
                     /translation="MQDLSLEARLAELESRLAFQEITIEELNVTVTAHEMEMAKLRDH
                     LRLLTEKLKASQPSNIASQAEETPPPHY"
     gene            complement(6906..7496)
                     /gene="slyD"
                     /locus_tag="RHX21_002564"
     CDS             complement(6906..7496)
                     /gene="slyD"
                     /locus_tag="RHX21_002564"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDV1987726.1"
                     /translation="MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLISG
                     LETALEGHEVGDKFDVAVGANDAYGQYDENLVQRVPKDVFMGVDELQVGMRFLAETDQ
                     GPVPVEITAVEDDHVVVDGNHMLAGQNLKFNVEVVAIREATEEELAHGHVHGAHDHHH
                     DHDHDGCCGGHGHDHGHEHGGEGCCGGKGNGGCGCH"
     gene            complement(7591..7791)
                     /locus_tag="RHX21_002565"
     CDS             complement(7591..7791)
                     /locus_tag="RHX21_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YheV family putative metal-binding protein"
                     /protein_id="HDV1987727.1"
                     /translation="MAIRKRFIAGAKCPACQAQDSMAMWRENNIDIVECVKCGHQMRE
                     ADKEARDHVRKDEQVIGIFHPD"
     gene            complement(7801..9606)
                     /gene="kefB"
                     /locus_tag="RHX21_002566"
                     /pseudo
     CDS             complement(7801..9606)
                     /gene="kefB"
                     /locus_tag="RHX21_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417809.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     protein KefB"
     gene            complement(9606..10157)
                     /gene="kefG"
                     /locus_tag="RHX21_002567"
     CDS             complement(9606..10157)
                     /gene="kefG"
                     /locus_tag="RHX21_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312229.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     ancillary protein KefG"
                     /protein_id="HDV1987728.1"
                     /translation="MSQPAKVLLLYAHPESQDSVANRVLLKPATQLSNVTVHDLYAHY
                     PDFFIDIPREQALLREHEVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLAG
                     KYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELAAGMCRMHWLSPIIIYWARRQSA
                     QELASHARAYGDWLANPLSPGGR"
     gene            10288..12201
                     /locus_tag="RHX21_002568"
     CDS             10288..12201
                     /locus_tag="RHX21_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDV1987729.1"
                     /translation="MIVFSSLQIRRGVRVLLDNATATINPGQKVGLVGKNGCGKSTLL
                     ALLKNEISADGGSYTFPGSWQLAWVNQETPALPQAALEYVIDGDREYRQLEAQLHDAN
                     ERNDGHAIATIHGKLDAIDAWSIRSRAASLLHGLGFSNEQLERPVSDFSGGWRMRLNL
                     AQALICRSDLLLLDEPTNHLDLDAVIWLEKWLKSYQGTLILISHDRDFLDPIVDKIIH
                     IEQQSMFEYTGNYSSFEVQRATRLAQQQAMYESQQERVAHLQSYIDRFRAKATKAKQA
                     QSRIKMLERMELIAPAHVDNPFRFSFRAPESLPNPLLKMEKVSAGYGDRIILDSIKLN
                     LVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLAKGIKLGYFAQHQLEYLRADE
                     SPIQHLARLAPQELEQKLRDYLGGFGFQGDKVTEETRRFSGGEKARLVLALIVWQRPN
                     LLLLDEPTNHLDLDMRQALTEALIEFEGALVVVSHDRHLLRSTTDDLYLVHDRKVEPF
                     DGDLEDYQQWLSDVQKQENQTDEAPKENANSAQARKDQKRREAELRAQTQPLRKEIAR
                     LEKEMEKLNAQLAQAEEKLGDSELYDQSRKAELTACLQQQASAKSGLEECEMAWLEAQ
                     EQLEQMLLEGQSN"
     gene            12201..13223
                     /locus_tag="RHX21_002569"
     CDS             12201..13223
                     /locus_tag="RHX21_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDV1987730.1"
                     /translation="MAQITTTDANEFSSSAEFTPMRGFSNCHLQTMLPRLFRRQVKFT
                     PYWQRLELPDGDFVDLAWSEDPAQAKHKPRLVVFHGLEGSLNSPYAHGLVEAAQKRGW
                     LGVVMHFRGCSGEPNRMHRIYHSGETEDASWFLRWLQREFGHAPTAAVGYSLGGNMLA
                     CLLAKEGNDLPVDAAVIVSAPFMLEACSYHMEKGFSRVYQRYLLNLLKANAARKLAAY
                     PGTLPINLAQLKSVRRIREFDDLITARIHGYADAIDYYRQCSAMPMLNRIAKPTLIIH
                     AKDDPFMDHQVIPKPESLPPQVEYQLTEHGGHVGFIGGTLLHPQMWLESRIPDWLTTY
                     LEAKSC"
     gene            13217..13435
                     /locus_tag="RHX21_002570"
     CDS             13217..13435
                     /locus_tag="RHX21_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YheU family protein"
                     /protein_id="HDV1987731.1"
                     /translation="MLIPWQDLSPETLENLIESFVLREGTDYGEHERTLEQKVADVKR
                     QLQCGEAVLVWSELHETVNIMPRSQFRE"
     gene            13489..14358
                     /locus_tag="RHX21_002571"
     CDS             13489..14358
                     /locus_tag="RHX21_002571"
                     /EC_number="2.7.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HDV1987732.1"
                     /translation="MSAKHPVIAVTGSSGAGTTTTSLAFRKIFAQLNLHAAEVEGDSF
                     HRYTRPEMDMAIRKARDAGRHISYFGPEANDFGLLEQTFIEYGQSGKGKSRKYLHTYD
                     EAVPWNQVPGTFTPWQPLPEPTDVLFYEGLHGGVVTPQHNVAQHVDLLVGVVPIVNLE
                     WIQKLIRDTSERGHSREAVMDSVVRSMEDYINYITPQFSRTHLNFQRVPTVDTSNPFA
                     AKGIPSLDESFVVIHFRNLEGIDFPWLLAMLQGSFISHINTLVVPGGKMGLAMELIML
                     PLVQRLMEGKKIE"
     gene            complement(14413..14817)
                     /locus_tag="RHX21_002572"
     CDS             complement(14413..14817)
                     /locus_tag="RHX21_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HDV1987733.1"
                     /translation="MQARVKWVEGLTFLGESASGHQILMDGNSGDKAPSPMEMVLMAA
                     GGCSAIDVVSILQKGRQDVVDCEVKLTSERREEAPRLFTHINLHFIVTGRDLKDAAVA
                     RAVDLSAEKYCSVALMLEKAVNITHSYEVVAA"
     gene            15119..15751
                     /gene="crp"
                     /locus_tag="RHX21_002573"
     CDS             15119..15751
                     /gene="crp"
                     /locus_tag="RHX21_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cAMP-activated global transcriptional regulator
                     CRP"
                     /protein_id="HDV1987734.1"
                     /translation="MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIV
                     KGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRAKTACEVAEISYKK
                     FRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
                     PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR"
     gene            15802..17892
                     /locus_tag="RHX21_002574"
     CDS             15802..17892
                     /locus_tag="RHX21_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312236.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDV1987735.1"
                     /translation="MWRRLIYHPDINYALRQTLVLCLPVAVGLMLGELRFGLLFSLVP
                     ACCNIAGLDTPHKRFFKRLIIGASLFATCSLLTQLLLAKDVPLPFLLTGLTLVLGVTA
                     ELGPLHAKLLPASLLAAIFTLSLAGYMPVWEPLLIYALGTLWYGLFNWFWFWIWREQP
                     LRESLSLLYRELADYCEAKYSLLTQHTDPEKALPPLLVRQQKAVDLITQCYQQMHMLS
                     AQNNTDYKRMLRIFQEALDLQEHISVSLHQPEEVQKLVERSHAEEVIRWNAQTVAARL
                     RVLADDILYHRLPTRFTMEKQIGALEKIARQHPDNPVGQFCYWHFSRIARVLRTQKPL
                     YARDLLADKQRRMPLLPALKSYLSLKSPALRNAGRLSVMLSVASLMGTALHLPKSYWI
                     LMTVLLVTQNGYGATRLRIVNRSVGTVVGLIIAGVALHFKIPEGYTLTLMLITTLASY
                     LILRKNYGWATVGFTITAVYTLQLLWLNGEQYILPRLIDTIIGCLIAFGGTVWLWPQW
                     QSGLLRKNAHDALEAYQEAIRLILSEDPQPTPLAWQRMRVNQAHNTLYNSLNQAMQEP
                     AFNSHYLADMKLWVTHSQFIVEHINAMTTLAREHRALPPELAQEYLQSCEIAIQRCQQ
                     RLEYDEPGSSGDANIMDAPEMQPHEGAAGTLEQHLQRVIGHLNTMHTISSMAWRQRPH
                     HGIWLSRKLRDSKA"
     gene            complement(17959..19179)
                     /gene="argD/dapC"
                     /locus_tag="RHX21_002575"
     CDS             complement(17959..19179)
                     /gene="argD/dapC"
                     /locus_tag="RHX21_002575"
                     /EC_number="2.6.1.11"
                     /EC_number="2.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     acetylornithine/succinyldiaminopimelate transaminase"
                     /protein_id="HDV1987736.1"
                     /translation="MAIEQTAITRATFDEVILPIYAPAEFIPVKGQGSRIWDQQGKEY
                     VDFAGGIAVTALGHCHPALVNALKTQGETLWHISNVFTNEPALRLGRKLIEATFAERV
                     VFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDG
                     FGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRELCDQ
                     HQALLVFDEVQCGMGRTGDLFAYMHYGVTPDILTSAKALGGGFPISAMLTTAEIASAF
                     HPGSHGSTYGGNPLACAVAGAAFDIINTPEVLEGIQAKRQRFVDHLQKIDQQYDVFSD
                     IRGMGLLIGAELKPQFKGRARDFLYAGAEAGVMVLNAGPDVMRFAPSLVVEDADIDEG
                     MQRFAHAVAKVIGA"
     gene            complement(19265..19828)
                     /gene="pabA"
                     /locus_tag="RHX21_002576"
     CDS             complement(19265..19828)
                     /gene="pabA"
                     /locus_tag="RHX21_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component 2"
                     /protein_id="HDV1987737.1"
                     /translation="MILLIDNYDSFTWNLYQYFCELGADVLVKRNDALTLADIDALKP
                     QKIVISPGPCTPDEAGISLDVIRHYAGRLPILGVCLGHQAMAQAFGGKVVRAAKVMHG
                     KTSPITHNGEGVFRGLANPLTVTRYHSLVVEPDSLPACFDVTAWSETREIMGIRHRQW
                     DLEGVQFHPESILSEQGHQLLANFLHR"
     gene            complement(19860..20462)
                     /locus_tag="RHX21_002577"
     CDS             complement(19860..20462)
                     /locus_tag="RHX21_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative adenosine monophosphate-protein
                     transferase Fic"
                     /protein_id="HDV1987738.1"
                     /translation="MSDKFGEGRDPYLYPGLDIMRNRLNIRQQQRLEQAAYEMTALRA
                     ATIELGPLVRGLPHLRTIHRQLYQDIFDWAGQLREVDIYQGDTPFCHFAYIEKEGNAL
                     MQDLEEEGYLVGLEKAKFVERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQL
                     SWQGIEKEAWNQANQSGAMGDLTALQMIFSKVVSEAGESE"
     gene            complement(20452..20619)
                     /locus_tag="RHX21_002578"
     CDS             complement(20452..20619)
                     /locus_tag="RHX21_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfG family protein"
                     /protein_id="HDV1987739.1"
                     /translation="MKKLTDKQKSRLWELQRNRNFQASRRLEGVEMPLVTLTAAEALA
                     RLEELRSHYER"
     gene            complement(20724..21296)
                     /gene="ppiA"
                     /locus_tag="RHX21_002579"
                     /gene_synonym="rotA"
     CDS             complement(20724..21296)
                     /gene="ppiA"
                     /locus_tag="RHX21_002579"
                     /gene_synonym="rotA"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase A"
                     /protein_id="HDV1987740.1"
                     /translation="MFKSTLAAMAAVFALSALSPAAMAAKGDPHVLLTTSAGNIELEL
                     DKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQQKKPNPPIKNEAD
                     NGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVAD
                     KISQVPTHDVGPYQNVPSKPVVILSAKVLP"
     gene            21567..22748
                     /gene="tsgA"
                     /locus_tag="RHX21_002580"
     CDS             21567..22748
                     /gene="tsgA"
                     /locus_tag="RHX21_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter TsgA"
                     /protein_id="HDV1987741.1"
                     /translation="MTNSNRIKLTWISFLSYALTGALVIVTGMVMGNIADYFNLPVSS
                     MSNTFTFLNAGILISIFLNAWLMEIVPLKTQLRFGFLLMVLAVAGLMFSHSLALFSAA
                     MFILGVVSGITMSIGTFLVTQMYEGRQRGSRLLFTDSFFSMAGMIFPMIAAFLLARSI
                     EWYWVYACIGLVYVAIFILTFGCEFPALGKHAPKTDAPVEKEKWGIGVLFLSVAALCY
                     ILGQLGFISWVPEYAKGLGMSLNDAGTLVSNFWMSYMVGMWAFSFILRFFDLQRILTV
                     LAGLAAILMYVFNTGTPAHMAWSILALGFFSSAIYTTIITLGSQQTKVPSPKLVNFVL
                     TCGTIGTMLTFVVTGPIVEHSGPQAALLTANGLYAVVFVMCFLLGFVSRHRQHNTLTS
                     H"
     gene            23010..25553
                     /gene="nirB"
                     /locus_tag="RHX21_002581"
     CDS             23010..25553
                     /gene="nirB"
                     /locus_tag="RHX21_002581"
                     /EC_number="1.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-nitrite reductase large subunit"
                     /protein_id="HDV1987742.1"
                     /translation="MSKVRLAIIGNGMVGHRFIEDLLDKSDAANFDITVFCEEPRIAY
                     DRVHLSSYFSHHTAEELSLVREGFYEKHGIKVLVGERAITINRQEKVIHSSAGRTVFY
                     DKLIMATGSYPWIPPIKGSDTQDCFVYRTIEDLNAIESCARRSKRGAVVGGGLLGLEA
                     AGALKNLGIETHVIEFAPMLMAEQLDQMGGEQLRRKIESMGVRVHTSKNTLEIVQEGV
                     EARKTMRFADGSELEVDFIVFSTGIRPRDKLATQCGLDVAPRGGIVINDSCQTSDPDI
                     YAIGECASWNNRVFGLVAPGYKMAQVAVDHILGSENAFEGADLSAKLKLLGVDVGGIG
                     DAHGRTPGARSYVYLDESKEIYKRLIVSEDNKTLLGAVLVGDTSDYGNLLQLVLNAIE
                     LPENPDSLILPAHSGSGKPSIGVDKLPDSAQICSCFDVTKGDLIAAINKGCHTVAALK
                     AETKAGTGCGGCIPLVTQVLNAELAKQGIEVNNNLCEHFAYSRQELFHLIRVEGIKTF
                     EELLAKHGKGYGCEVCKPTVGSLLASCWNEYILKPEHTPLQDSNDNFLANIQKDGTYS
                     VIPRSPGGEITPEGLMAVGRIAREFNLYTKITGSQRLAMFGAQKDDLPEIWRQLIEAG
                     FETGHAYAKALRMAKTCVGSTWCRYGVGDSVGLGVELENRYKGIRTPHKMKFGVSGCT
                     RECSEAQGKDVGIIATEKGWNLYVCGNGGMKPRHADLLAADIDRETLIKYLDRFMMFY
                     IRTADKLTRTAPWLENLEGGIDYLKAVIIDDKLGLNAHLEEEMARLREAVVCEWTETV
                     NTPSAQTRFKHFINSDKRDPNVQMVPEREQHRPATPYERIPVTLVEDNA"
     gene            25550..25876
                     /gene="nirD"
                     /locus_tag="RHX21_002582"
     CDS             25550..25876
                     /gene="nirD"
                     /locus_tag="RHX21_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite reductase small subunit NirD"
                     /protein_id="HDV1987743.1"
                     /translation="MNQWKDICKIDDILPETGVCALLGDEQVAIFRPYHSDQVFAISN
                     IDPFFESSVLSRGLIAEHQGELWVASPLKKQRFRLSDGLCMEDEQFSVKHYEARVKDG
                     VVQLRG"
     gene            26003..26809
                     /gene="nirC"
                     /locus_tag="RHX21_002583"
     CDS             26003..26809
                     /gene="nirC"
                     /locus_tag="RHX21_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026212.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite transporter NirC"
                     /protein_id="HDV1987744.1"
                     /translation="MFTDTINKCAANAARIARLSANNPLGFWVSSAMAGAYVGLGIIL
                     IFTLGNLLDPSVRPLVMGATFGIALTLVIIAGSELFTGHTMFLTFGVKAGSISHGQMW
                     AILPQTWLGNLVGSVFVAMLYSWGGGSLLPVDTSIVHSVALAKTTAPAMVLFFKGALC
                     NWLVCLAIWMALRTEGAAKFIAIWWCLLAFIASGYEHSIANMTLFALSWFGNHSEAYT
                     LAGIGHNLLWVTLGNTLSGAVFMGLGYWYATPKANRPVADKFNQTETAAG"
     gene            26828..28201
                     /gene="cobA"
                     /locus_tag="RHX21_002584"
     CDS             26828..28201
                     /gene="cobA"
                     /locus_tag="RHX21_002584"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HDV1987745.1"
                     /translation="MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALA
                     FIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARRIFCNV
                     VDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQ
                     LRGRVKQQFATMGERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEV
                     VLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHC
                     VPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNAGIPFSVVPGITAAS
                     GCSAYSGIPLTHRDYAQSVRLITGHLKTGGELDWENLAAEKQTLVFYMGLNQAATIQQ
                     KLIEHGMPGEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDK
                     LNWFSNH"
BASE COUNT         6881 a         7614 c         7159 g         6739 t
ORIGIN      
        1 cagtcgcagc aactaccagg atcgcgccgt ccatctgagc agcaccggtg atcatgtttt
       61 taacatagtc ggcgtgcccc gggcagtcta cgtgtgcgta gtgacgggtc ggggtgtcat
      121 attcaacgtg agaagtgttg atggtgatac cacgagcttt ttcttccggc gcgttatcga
      181 tctggtcgaa tgcacgagca gcaccgccgt aggttttagc cagtacggtg gtgattgcag
      241 cggtcagagt agttttaccg tggtcaacgt ggccgatagt accaacgtta acgtgcggtt
      301 ttgtacgttc aaatttttct ttagacacgg ctatattcct tactatagtg ctctcccctt
      361 caggagagag cacgggactt tggtattaac ccttaggctt atttaccacg ggcttcaatt
      421 acggcctgag caacgttact cggcgcttca tcatacttca ggaattccat agtgtatgat
      481 gcacgacctt tggtcagaga acgcagctga gttgcgtatc cgaacatttc agacagcggt
      541 acttcagcgt ggatcttaac gccagtaact tcagattcct gacctttgag cataccacga
      601 cgacggctca agtcaccgat aacgtcaccg gtgttctctt ccggagtttc tacttcaacc
      661 ttcatgatcg gctcaagcag aactggtttc gctttcttaa agccttcttt aaaggcgata
      721 gaagcagcca gtttaaacgc cagttcagag gagtcaacgt catggtaaga accgaagtgc
      781 agacgaatac ccatgtctac taccgggtag cctgccagcg gacctgcttt cagctgttcc
      841 tggatacctt tatcaacggc cgggatgtat tcgccaggga ttacaccacc tttaatgtcg
      901 ttgatgaact cgtagccttt cgggtttgaa cccggctcca gcgggtacat gtcgataaca
      961 acatgaccat actgaccacg accaccagac tgtttcgcgt gtttaccttc aacatcggta
     1021 actttctggc ggatagtttc acggtaagca acctgcggtt tacctacgtt cgcttcaacg
     1081 ttgaattcac gcttcatacg gtcaacgatg atgtcgaggt gcagttcgcc catacccgcg
     1141 ataatggtct ggttagattc ttcgtcagtc catacacgga aagacgggtc ttctttagcc
     1201 agacggccca gagccagacc cattttttcc tggtcagctt tggttttcgg ttcaactgcg
     1261 atggagatta ccggctcagg gaattccata cgttccagaa tgatcggcgc atccgggtca
     1321 cacagggtgt caccagtggt tacgtctttc agaccgatag cagcagcgat gtcgcccgcg
     1381 cgaacttctt tgatctcttc acgtttgtta gcgtgcatct gaacgatacg accgaaacgc
     1441 tcacgtgcag ctttcacgga gttcagtacg gtatcaccag agttaaccac accggagtaa
     1501 acacggaaga aggtcaggtt accaacaaac gggtcggtag cgattttgaa cgccagtgca
     1561 gagaacggct catcatcact tgcgtgacgc tcagccggag tgtctttacc gtcgtccagg
     1621 ataccgttga tcgcaggtac gtcaaccggg gatggcaggt aatcaattac cgcatccagc
     1681 atcgcctgaa cacctttgtt cttgaacgca gaaccacagg ttaccaggat gatttcgttg
     1741 ttcagaacgc gctgacgcag agcacctttg atttctgctt cagtcagttc ttcaccaccc
     1801 aggtattttt ccatcagctc ttcagaagct tcagctgcgg attcgatcag gttctggtgc
     1861 cattcgttag ccagttcaac catgtctgcc gggatatctt cgtattcgaa ggttacgccc
     1921 tggtcagcgt cgttccagtt gatagctttc attttcacca ggtcaacaac accggtgaaa
     1981 tgttcttcag caccaatcgc cagctgcagc ggaaccgggt tcgcgcccag acgggttttg
     2041 atctggttaa caactttcag gaagttcgca cccatgcggt ccattttgtt aacgaacgca
     2101 atgcgcggaa ctttatattt gtttgcctga cgccatacgg tttcagactg cggctgaaca
     2161 ccaccaactg cgcagtaaac cattaccgca ccatcgagaa cacgcatgga acgttctact
     2221 tcgattgtga agtcaacgtg ccccggggtg tcgatgatgt tgatgcgatg cggctcatac
     2281 tgcttagcca taccagacca gaatgcagta gtcgcagcgg aagtgatggt aataccacgt
     2341 tcctgctcct gctccatcca gtccatggtt gcagcgccgt catgaacttc accgatttta
     2401 tggtttacac cggtgtagaa cagaatacgt tcggtagtag tggttttacc ggcgtcgatg
     2461 tgcgcactga taccgatatt acggtagcgt gcgatgggtg ttgtacgagc catttgtttc
     2521 ctcgtttatc ttttaggcgt tcaatttaag tagcccaaag cgggctgctt actggaagcg
     2581 cccgcctggt gactaaaact ccgaagggat taccaacggt agtgtgcgaa cgccttgttg
     2641 gcttcggcca tacggtgaac gtcttcacgt ttcttaactg cagtaccttt gttttctgca
     2701 gcatcagaaa gttcgttcgc caggcgcaga gccatggatt tatcaccgcg tttacgagca
     2761 gcttcaacga tccaacgcat tgccagagca ttacgacgaa ccggacggac ttcaactggt
     2821 acctgataag tagaaccacc aacgcggcga gacttaactt ctacagtcgg gcgcacgttt
     2881 tcgagagcta cttcgaatgc ttccagttca gatttaccag agcgctgagc cagggtctcc
     2941 agcgcgctgt atacgataga ttcagcagta gattttttac catctaccat caggatattt
     3001 acaaatttag ccagcagttc tgatccgaac ttcggatccg gcagaatttt acgctgacca
     3061 atgacgcgac gacgtggcat ggaaatactc cgttgttaat tcaggattgt ccaaaactct
     3121 acgagtttag tttgacattt aagttaaaac gtttggcctt acttaacgga gaaccattaa
     3181 gccttaggac gcttcacgcc atacttggaa cgagcctgct tacggtcttt aacgccggag
     3241 cagtcaagcg caccacgtac ggtgtggtaa cgaacacccg ggaggtcttt aacacgaccg
     3301 ccacggatca ggatcacgga gtgctcctgc aggttgtgac cttcaccacc gatgtaggaa
     3361 gtcacttcga aaccgttagt cagacgaaca cggcatactt tacgcagcgc ggagttcggt
     3421 tttttaggag tggtagtata tacacgagta catacgccac gtttttgcgg gcatgcttcc
     3481 agcgcaggca cgttgctttt cgcaactttg cgagcacgtg gtttgcgtac cagctggtta
     3541 actgttgcca ttaaatagct cctggtttta gcttttgctt cgtaaacacg taataaaacg
     3601 tcctcacaca atatgaggac gccgaatttt agggcgatgc cgaaaaggtg tcaagaaata
     3661 tacaacgatc ccgccatcac caggccatct ggctggagtg cttaaccgta agtctgacga
     3721 aatcagtata gtcaatggga ataatgtcgt tcgaaatttg accagtcaaa ccgcgggcaa
     3781 taaggtcttc gttcagggca tagaccttaa tgggggcatt acgcagactt tcaaggtagc
     3841 ggttaccgtc aactgcggca gttacaccat cttgcaataa tagcagttcg tcgccctcac
     3901 tgagcagacg cagcagcgca gcaaaatccg tcagccaggg tgaacgatgt aatgtgtgca
     3961 gcataaacgc ctcaaaacct caaaataaca tcgtagttgg cgagttcgcg gcgtaaggca
     4021 tctgcttcga gcggcgtggc ttcgacaaca aagggtgtct gcggatctaa cccgcgttcg
     4081 cgcagtgaag ccgcacaaac ccagcactgt tcaatgtcgt acagacccaa caatttaaaa
     4141 gtggcaatgt aatcacgcgc cagcactgca tcgggctttt gtcctgacag cagctgaaaa
     4201 acgccatcag cgataaagaa gacggccaga tcgtcagtta atgcggaagt tgccagtaaa
     4261 gcatctaaac cttcccgacc agcagctgta ccatgaggtg cagtagaaaa aacaaacgca
     4321 attcgtttca tcagaactgt accaccctgt cacaggtcag cgaggcttcc gccagcgccc
     4381 caagtccgct taaggtaaat cctggctgaa ggtttgacga agccagcccc agccttcctg
     4441 cttcagtttc atcgacgata ccgcggcgta acgctgccgc tacgcagata ttcagcgcca
     4501 caccatgttg cgcattcaac tgttgccagc cgcgcacaag gtcaaattcg tcacttgccg
     4561 gtgaggtcaa ttggttagcg ttatagaccc cttcccgata gaaaaagacg ctgcttaact
     4621 catggccttc ggctatcagc gcctgcgcaa actgaaaagc actactcgcc tgttgcgtac
     4681 cgtatgctgg cccggtcacc acgatggcaa aacgcattac ttatcttgcc ccaggaagtc
     4741 gccacttttg aactggcgaa tatagagata aacagtatgt ttggaaatat tcagacgatc
     4801 agcaacctga ttaatcgcgt cttttatgtc gaatatccct ttctcgtaga gattcaatac
     4861 gatctggcga tttttggcgt tattagaaac attgcgatcg gcattcactt cttcgatggt
     4921 gaactccagc gtttgggtaa ccagatcttc tacagaggaa gcaaagttga catttgagcc
     4981 gacatccggc gtctctggtg gcacgaaggt gctcataatc tgcgagaaag gaacatcgag
     5041 gttcatatta atgcacagca ggccaattac acgctgttcg cgattacgaa tggcgatggt
     5101 cagcgacttc attaatacgc cgcttttggc gcgagtaaag tagcatttag aaacgctgct
     5161 atccgctccc gtcatatcgt gaagcatacg tagcgccagg tcggtaattg gcgaaccaat
     5221 cttccggcct gtatgttcac cgttagcaat acgaatggct gaacatttta aatcctgcaa
     5281 agagtgcaaa acgatttcac agtgggagcc aatgagcatc gctaacccgt ccaccaccgc
     5341 ttcgtaggat ttcagaatat caaaatcgct ctggtcgaaa ggacgttgat ccagtaaatc
     5401 caactcactg gtttcgttgg ttaaaagcga cctggacatg aaaaaaaaca ctccttttca
     5461 ggagcctgtc gttaactttt cagggcaggc tcattaatga tgcgggtaac taaattaata
     5521 cagcggaggt tccgctttcc agcactaatt atatccggcc tgtaataaaa aaaccgccgc
     5581 ctggtcaggc ggcggttctt aatgcttatt ttttagcaga atctgcggct ttcgcatcag
     5641 cttccggctt tgcatcagcc ttcggcgctg gtttcacatc cagcagctct acgtcaaaca
     5701 ccagggtaga attcggtggg atccccggaa cacccgcttt gccgtaagcc agttctggtg
     5761 gaataaccag tttgatctta ccgcctttct tgatgttctt cagaccttct gtccaacccg
     5821 ggataacacc gtccagacgg aaagaaagcg gttcaccacg ggtgtaagag ttgtcgaact
     5881 ctttaccgtc gatcagcgta cctttgtagt tcactacaac agtatcgctg tctttcggtg
     5941 cttcgccttt accggcttct actacctgat aaaccagacc agttgaagag gttttcacac
     6001 ctttctcttt ggcaaatttc tcgcggtact ctttaccttt tgcttcgtta tcagccgcgt
     6061 ctttttccat cttcgcctga gcagaagact tcacgcgagc ttcgaatgct tgcagagtct
     6121 gttcgatctc ttggtcggag agtttgctct tatcagcaaa tgcatcctga acaccagcga
     6181 tcagctgatc tttatccagt ttgatgccca gtttttcttg ttctttaaga gagttttcca
     6241 tgtaacgacc cagcgaagca cccagtgcat aagctgattt ctgatcgtca tttttgaacg
     6301 ctgctttgct gtcagcagtt gtagcaggtt ttgcagcttc agcagcaaaa gtgattggtg
     6361 catgcagggc aacggccatt gtggtcgcca gcagcgttac tttaaacagt gatttcatcc
     6421 atatctccag gatcggggca tctcacccca gggttaacta ttatcagaag ggtactataa
     6481 agcgttgtcg aacaaatcta catacagaca cgccctatta tcatctattt tcagactctt
     6541 tttgtttaaa ttagtttcga tgaccgcgaa atgagtgctg tctcgggcag caaagttaag
     6601 tagaatccgc ggcgaccatt cgacaaaaga ggtgaatcat gcaggattta tcattggaag
     6661 cacgcctggc agagctggag agccgactgg cttttcagga aatcaccatt gaagaactga
     6721 acgtcacggt gaccgctcat gaaatggaga tggcgaaact gcgcgatcat ctgcgtctgc
     6781 tgaccgagaa gttaaaagcc agccagccgt cgaacatcgc gtcgcaggct gaagaaacgc
     6841 caccgccaca ttattgaggc gtaaaaaaag cggggattcc ccgctttttt gtcacctttt
     6901 cggtattagt ggcaaccaca accgccgttg cctttaccgc cacagcagcc ttcgccaccg
     6961 tgttcatgac cgtgatcgtg gccatgaccg ccgcagcaac cgtcgtggtc gtgatcgtgg
     7021 tgatgatcgt gcgcgccgtg aacgtggcca tgagccagtt cttcttcggt cgcttcgcga
     7081 atcgccacaa cttcaacgtt gaatttcagg ttctgaccgg ccagcatgtg gttaccatca
     7141 accacgacgt gatcgtcttc aaccgcagtg atttcaaccg gtaccggacc ctggtcagtt
     7201 tcagccagga aacgcatacc tacctgcagt tcatcaacgc ccataaatac gtctttagga
     7261 acacgttgca ccaggttttc gtcgtactga ccgtaagcgt cgttcgcgcc aacagcgaca
     7321 tcaaatttgt cgccaacttc atgaccttcc agcgccgttt ccaggccaga gatcagggaa
     7381 ccgtgaccat gcaggtagtc cagcggcgca ctcaccggag actcatcaac caacacaccg
     7441 tcttctgtac gtacctgata ggccaggctg accaccaggt cttttgctac tttcatgata
     7501 tctcctgagc atgggaagaa tagtggcgca gattgtagcg gaattctgca gccgtgtact
     7561 cactagctta aaaaaactcg gcgcatatcg ctagtccgga tgaaaaatcc cgatcacttg
     7621 ctcatctttg cgaacgtgat cgcgggcttc tttgtctgct tctcgcatct gatgtccgca
     7681 cttaacacat tcaacaatat caatattatt ttcgcgccac atcgccattg aatcctgcgc
     7741 ctgacaggcc gggcattttg cgcccgcaat aaaacgtttt cggattgcca tctttaccct
     7801 ctactcaaat tcatcccagc cgtccagctg gcgtcgttct tgttgcattt cacgctggaa
     7861 aatctcttcc agttcgcgtc gggcttccct ggcgcgagaa atttgtacgg tatcagcatg
     7921 catcgggatt aactcccgca gcattcgcat atccaggcgg cgaaaatgca gttgcgcccg
     7981 ctgtgcctga tgcggatgca tgccaagcgt gaccagcgtc ttgcgcccca gctctaacgc
     8041 actggagaat gtttcacggg aaaactgcgt cacccctgcc tgtaataact catgcgcttc
     8101 cacacgtccg cgcgctcgcg caagaatatg caaatgcgga aagtgctgct ggcatatttc
     8161 caccagcttc atggtgtctt ccggctcgtt acaggtaatg acgatagact cagcggcctc
     8221 tgcacccgca gaacgtaaaa gatcgacctg cgtggcgtcg ccgtaataaa ctttgtagcc
     8281 atatttacgc atcaggttaa cggcgctgat atcccgctcc agcacggtaa tgcgcatttt
     8341 atttgccatc agcaaacgac caatcacctg accaaaacgc ccgaagccca cgacaatgac
     8401 ctggggttta tcatcgttga cccacggttt ttcgtcttct tcttccggtc cgttaaactg
     8461 gcgggatagc catttatcca ccagcttcat cagcaacggc gtggtcatca tggaaagcgt
     8521 caccgtcacc agcaacagcg ccatctggtc gccctggaat aaacgttgtg aagaagcggt
     8581 agaaaagagg acaaaggcaa actcaccgcc ctgactcaac acgccagcaa actgcatccg
     8641 ctctgagcta cgcacgccat acaatcgcgc cagcagatac aacacgagaa ttttcaccgc
     8701 caccagcaca accacgctta tcactaccca caacagatgg gtataaagca ccccgagatt
     8761 gagcgacatg ccgacagaga taaagaacaa accgagcagc aagcctttga agggatcgat
     8821 agccgtttcc agttcatggc gatattcact ttccgccagc agcacgcccg caataaacgt
     8881 accgagcgcc atcgacagcc ccagcgcgtc cataaacaat gcggaaccca acaccaacag
     8941 cagcgtcgcg gcggtgaaca cttcccgcac gccagaagct gcaataaaac ggaataccgg
     9001 acgcagtaaa tagcgcccgc caatcagcat gccgacaaac gccagcacct tcatgccgat
     9061 cttcatccag tcgaaatgtt cgtctgccga acccgccaac aacggcactc acgccagtgc
     9121 cgggatcacc gccagatcct gaaacagcag aaccgaaaac ccgagctgcc cggattcgct
     9181 gcgattcatc cctttctcac gcatcaattg caacgccatt gcagttgaag acatcgcaag
     9241 gccaatgcca ccgacaaccg ccgcctgcca ggcgaaatcc gtcagcatca ataatcccgc
     9301 cagcaacgcc gcgcttaaca gcacctgtgc cgcgcctacg ccaaaaatcg aacgccgcag
     9361 ttgccaaagt ttggagggat tcaactcaag accgatgata aacatcagga ataccacgcc
     9421 gagttccgaa aagtggagga tctcatcgac gtcgctaata aaccccagcc cccatggacc
     9481 aattgcaatt cctgccagca aatatcccaa cacagcgcca atacccagcc gcgatgccag
     9541 cggcaccgca gccaccgccg cgaagagaaa cagcactcct gcgagtaaaa aatcggaacc
     9601 ttccatcagc ggcctcctgg agacagcgga tttgccagcc agtcaccgta ggctctggcg
     9661 tgactcgcca gctcctgtgc gctttgccgt ctcgcccagt aaataatgat gggacttaac
     9721 caatgcatcc ggcacatgcc cgccgccagt tcaaagggac gcagaacatc gctcatcggg
     9781 tagcgattca atgcgtcata acggtaagca ctttccggct cgccggtggt aatcacgcta
     9841 cgccagtact ttcccgccag ttggtttcct cccggcccgc tggcaaaacc acgacttaat
     9901 acccggtcca gccactcttt cagtagcgcc gggcagctat aggtataaag aggatgctga
     9961 aagacaatca cctcgtgctc gcgcagtaat gcctgctcac gggggatatc aataaaaaaa
    10021 tcgggatagt gcgcataaag gtcgtgcacg gtaacattgc tgagctgcgt ggccggttta
    10081 agcagtaccc ggtttgccac cgagtcctga gattccggat gggcatacag cagcaaaact
    10141 ttcgctggct gagacatcat ccccctcccg gtatggtttt tgtgtatagt cgctgttttg
    10201 ggctaccatt gcgcccggtg cggcagctcg cccatacatt acattatcat aatgataagt
    10261 taacatagtc tgaacatacg gcgccttatg attgttttct cctcgttaca aattcgtcgc
    10321 ggcgtgcgcg tcctgctgga taatgccacc gccaccatca accctgggca gaaagtcggc
    10381 ctggtgggta aaaacggctg tggtaaatct accctgctgg cattgctgaa aaatgaaatc
    10441 agcgccgacg gcggcagcta cacctttccg ggaagctggc aactggcgtg ggtgaatcag
    10501 gaaacgccgg cgttaccgca agcggcgctg gaatatgtca ttgacggcga ccgtgaatat
    10561 cgtcaactag aagcgcagct acacgacgcc aacgaacgta acgacgggca cgccattgcg
    10621 accattcatg gcaagctgga tgctattgac gcatggagta ttcgctcccg tgccgccagc
    10681 ctgctgcacg gcctcggttt cagcaatgaa caactggagc gcccggtaag tgatttctcc
    10741 ggtggctggc gtatgcgtct taaccttgcc caggcgctga tttgccgttc agacttgctg
    10801 ctgctcgacg aaccgactaa ccacctcgat ctcgatgccg ttatctggct ggaaaaatgg
    10861 ttgaagagct atcagggcac gctgatcctg atctctcacg accgcgactt cctcgatccg
    10921 atcgttgata aaattattca tatcgaacaa caaagcatgt tcgagtacac cggcaactac
    10981 agttcgtttg aagtacagcg cgccacccgt ctggcgcagc aacaagcgat gtatgaaagc
    11041 cagcaggaac gcgtagcgca tctgcaaagt tatatcgacc gtttccgtgc caaagccacc
    11101 aaagcgaagc aggcccagag ccgcattaag atgctcgagc gtatggagct gattgccccc
    11161 gcgcacgtcg acaacccgtt ccgctttagc ttccgcgcgc cggaaagcct gccaaatccg
    11221 ttactgaaga tggaaaaagt cagcgcgggc tatggcgatc gcattattct cgactcgatt
    11281 aaactgaacc tggtgcccgg ctcgcgcatt ggtctgttag gccgcaacgg cgcgggtaaa
    11341 tcgacattaa tcaaactgtt agccggtgaa cttgcgccag tcagcggtga aattggtctg
    11401 gcgaaaggga tcaagctcgg ctacttcgcc cagcatcaac ttgaatacct gcgcgccgac
    11461 gaatcaccta ttcaacatct ggcacgttta gcgccgcagg agctggaaca aaaactgcgt
    11521 gactacctcg gcggctttgg tttccagggc gataaagtaa ccgaagaaac gcgccgcttc
    11581 tcaggtgggg aaaaagcccg cctggtgctg gcattaattg tctggcagcg tccgaatctg
    11641 ctgctgctcg acgaaccgac taaccacctt gacctcgaca tgcgtcaggc actcaccgaa
    11701 gcattaatcg agtttgaagg cgcgctggtt gtcgtttcgc acgaccgtca tttgctgcgt
    11761 tccaccactg acgatctcta cctggttcac gatcgtaaag tcgaaccgtt cgacggcgat
    11821 ctggaagatt atcaacagtg gttgagcgac gtacaaaagc aggaaaacca gaccgacgaa
    11881 gcgccaaaag agaacgcgaa cagcgcccag gcacgtaaag atcagaagcg tcgggaagcg
    11941 gagctgcgtg cgcaaaccca gccgctgcgt aaagagattg cccgtctgga aaaagagatg
    12001 gagaagctga acgcgcaact ggcgcaggcg gaagagaaac tcggcgacag cgaactgtat
    12061 gaccagagcc gtaaagcgga gttgaccgcc tgcctgcaac agcaagccag cgccaaatcc
    12121 ggcctggaag agtgcgaaat ggcgtggctg gaagcccagg agcagcttga gcagatgctg
    12181 ctggaaggcc aaagcaactg atggcgcaga taacgacgac cgatgccaat gaatttagca
    12241 gcagtgctga attcacccct atgcgcggct ttagcaattg tcatctacaa actatgctgc
    12301 cgcgtttgtt tcgtcgtcag gtgaaattca ccccgtactg gcagcggctg gagttgcccg
    12361 acggcgattt tgtcgatctc gcgtggagtg aagaccccgc acaggcgaaa cataaaccgc
    12421 gtttagtggt gtttcacggg ctggaaggca gtctcaatag cccttacgcc cacggtctgg
    12481 ttgaggcggc gcaaaagcgc ggctggctgg gcgtggtgat gcattttcgc ggatgcagcg
    12541 gtgaaccaaa ccgtatgcac cgcatttacc attcgggcga aaccgaagac gccagttggt
    12601 ttttacgctg gctgcaacgc gaatttggtc atgcgccaac ggctgccgtc ggctattcgc
    12661 tcggcggtaa tatgctggcc tgtttgctgg caaaggaagg caatgatctc ccggttgatg
    12721 cggcggtgat tgtctctgcg ccgtttatgc tggaagcctg tagctatcat atggaaaagg
    12781 gcttttcccg cgtttatcag cgttacttgc taaacctgtt aaaagccaat gccgcacgca
    12841 agctggcagc ctaccccgga acactgccga ttaatctcgc gcagttaaaa tcggtacgtc
    12901 gcatccgtga atttgacgat ctaatcaccg ccagaattca cggctacgct gacgctatcg
    12961 actattatcg tcagtgtagc gccatgccga tgctgaaccg gatcgccaaa cctacgctga
    13021 ttattcacgc caaagacgat ccgtttatgg atcatcaggt gatcccgaaa ccggaaagtc
    13081 tccccccgca ggttgagtat caactgactg aacatggcgg tcatgttggc tttattggcg
    13141 gtacattact tcatccgcaa atgtggctgg agtcacgcat tcctgactgg ttaacaacgt
    13201 atctggaggc gaaatcatgt tgattccgtg gcaagacctc tcccccgaaa cgctggaaaa
    13261 tttaattgaa agctttgtgt tacgtgaagg caccgattat ggtgaacatg agcgtacact
    13321 tgaacagaaa gtcgccgacg tcaaacgcca gctacagtgc ggagaagcgg tgctggtatg
    13381 gtcggagctg cacgaaacgg tcaatattat gccgcgcagt cagtttcgcg aataacctgc
    13441 aaccgtcggc ggacgagata ataatgatag ctaagtcatg gagttactat gtctgccaaa
    13501 catccggtca ttgcggtaac aggatccagc ggcgcgggga ccaccaccac cagcctcgcg
    13561 tttcgtaaaa tattcgcgca gttaaatctg catgcagctg aggtggaagg cgacagtttt
    13621 caccgttaca cccgcccgga aatggacatg gcgatccgca aagcgcgcga cgccgggcgg
    13681 catatcagct acttcggccc cgaggctaac gacttcggcc tgctggaaca aaccttcatt
    13741 gaatacggtc agagcggcaa agggaaatct cgcaaatatc tgcataccta cgacgaagcc
    13801 gtaccgtgga atcaggtacc ggggacattc accccctggc aacctttacc ggaacccact
    13861 gatgtactgt tttatgaagg tttacacggc ggcgtagtca cgccacagca taacgttgcg
    13921 cagcatgtgg acttactggt cggcgtggtg cctatcgtta accttgagtg gattcaaaaa
    13981 ctgatccgcg acaccagcga gcgcgggcac tcacgagaag cagtgatgga ctcggtagtg
    14041 cgttcaatgg aagattatat caactacatc acaccgcagt tttcccgcac ccatcttaac
    14101 ttccagcgcg ttcccaccgt cgacacttca aacccgttcg cggcaaaagg tatcccgtcg
    14161 ctcgatgaaa gctttgtggt gatccatttt cgtaatctgg aagggatcga tttcccctgg
    14221 ctgctggcga tgttgcaagg ctcattcatt tcccacatca atacgttagt ggtaccgggc
    14281 ggcaaaatgg gtctggcaat ggaattaatt atgctgccgc tggtgcaacg attgatggaa
    14341 ggaaagaaaa tcgagtaact ctgctattac gccggataaa atactatccg gcttcacaac
    14401 gggatagtta aatcacgcgg caaccacttc atacgagtga gtaatattca ccgctttttc
    14461 cagcatcaac gccactgaac aatatttctc agcagagaga tcaaccgcac gcgcaaccgc
    14521 tgcgtctttc aggtcgcgac cggtgacgat aaaatgcaga ttaatgtgcg taaacaggcg
    14581 tggtgcctct tcgcggcgtt cagaggtcaa ttttacttca caatcgacca catcctgacg
    14641 ccctttttgc aggatagaaa ccacatcgat ggcactgcaa ccccccgccg ccatcaacac
    14701 catttccatc ggacttggtg ctttatcgcc tgagttgccg tccattaaaa tctgatgacc
    14761 agaggcggat tcgcccagaa aagttaaccc ttcgacccac ttcactcgcg cttgcatttt
    14821 tgctactcca ctgcgtcaat tttcctgaca gagtacgcgt actaaccaaa tcgcgcaacg
    14881 gaaggcgacc tgggtcatgc tgaagcgaga caccaggaga cacaaagcga aagctatgct
    14941 aaaacagtca ggatgctaca gtaatacatt gatgtactgc atgtatgcaa aggacgtcac
    15001 attaccgtgc agtacagttg atagcccctt cccaggtagc gggaagcata tttcggcaat
    15061 ccagagacag cggcgttatc tggctctgga gaaagcttat aacagaggat aaccgcgcat
    15121 ggtgcttggc aaaccgcaaa cagacccgac tctcgaatgg ttcttgtctc attgccacat
    15181 tcataagtac ccatccaaga gcacgcttat tcaccagggt gaaaaagcgg aaacgctgta
    15241 ctacatcgtt aaaggctctg tggcagtgct gatcaaagac gaagagggta aagaaatgat
    15301 cctctcctat ctgaatcagg gtgattttat tggcgaactg ggcctgtttg aagagggcca
    15361 ggaacgtagc gcatgggtac gtgcgaaaac cgcctgtgaa gtggctgaaa tttcgtacaa
    15421 aaaatttcgc caattgattc aggtaaaccc ggacattctg atgcgtctgt ctgcacagat
    15481 ggcgcgtcgt ctgcaagtca cttcagagaa agtgggcaac ctggcgttcc tcgacgtgac
    15541 gggccgcatt gcacagactc tgctgaatct ggcaaaacaa ccagacgcta tgactcaccc
    15601 ggacggtatg caaatcaaaa ttacccgtca ggaaattggt cagattgtcg gctgttctcg
    15661 tgaaaccgtg ggacgcattc tgaagatgct tgaagatcag aacctgatct ccgcacacgg
    15721 taaaaccatc gtcgtttacg gcactcgtta atcccgtcgg agtggcgcgt tacctggtag
    15781 cgcgccattt tgtttccccc gatgtggcgc agactgattt atcaccccga tatcaactat
    15841 gcacttcgac aaacgctggt gctatgtttg cccgtggccg ttgggttaat gcttggcgaa
    15901 ttacgattcg gtctgctctt ctcactcgtt cctgcctgtt gcaatattgc gggccttgat
    15961 acgcctcata aacgtttttt caaacgctta atcattggtg cgtcgctgtt tgccacctgt
    16021 agcttgctga cacagctact actggcaaaa gatgttcctc tgcccttttt gctgaccgga
    16081 ttaacgctgg tacttggcgt cactgctgag ctggggccat tgcacgctaa attgcttccc
    16141 gcatcgctgc tcgccgccat ttttaccctc agtctggcgg gatatatgcc ggtctgggaa
    16201 ccattgctca tctatgcgtt gggcactctc tggtacggat tgtttaactg gttttggttc
    16261 tggatctggc gcgaacaacc gctgcgcgag tcactaagtc tgctgtaccg tgaactggca
    16321 gattattgtg aagccaaata cagcctgctt acccagcaca ccgaccctga aaaagcgctg
    16381 ccgccgctgc tggtgcgcca gcaaaaagcg gtcgatctaa ttacccagtg ctatcagcaa
    16441 atgcatatgc tttccgcgca aaataatact gactacaagc ggatgctgcg tattttccag
    16501 gaggcgctgg atttacagga acatatttcg gtcagtttgc atcagccgga agaggtgcaa
    16561 aaactggtcg agcgtagcca tgcggaagaa gttatccgct ggaatgcgca aaccgtcgcc
    16621 gctcgcctgc gcgtgctggc tgatgacatt ctttaccatc gcctgccaac gcgttttacg
    16681 atggaaaagc aaattggcgc actggaaaaa atcgcccgcc agcatccgga taatccggtt
    16741 gggcaattct gctattggca cttcagccgc attgcccgcg tgctgcgcac ccaaaaaccg
    16801 ctctatgccc gtgacttact ggccgataaa cagcggcgaa tgccgttact tccggcgctg
    16861 aaaagttatc tgtcactaaa gtctccggcg ctacgcaatg ccggacgact cagtgtgatg
    16921 ttaagcgttg ccagcctgat gggcaccgcg ctgcatctgc cgaagtcgta ctggatcctg
    16981 atgacggtat tgctggtgac gcaaaatggc tatggcgcaa cccgtttgag gattgtgaat
    17041 cgctccgtgg gaaccgtggt cgggttaatc attgcgggcg tggcgctgca ctttaaaatt
    17101 cccgaaggtt acaccctgac cttgatgctg attaccaccc tcgccagcta cctgatattg
    17161 cgcaaaaact acggctgggc gacggtcggt tttaccatta ccgcagtgta taccctgcaa
    17221 ctgttgtggc tgaacggtga gcagtacatc cttccacgtc ttatcgatac cattattggt
    17281 tgtttgattg ctttcggtgg taccgtctgg ctgtggccgc agtggcagag cgggttattg
    17341 cgtaaaaacg cccatgatgc tttagaagcc tatcaggaag cgattcgctt gattctgagc
    17401 gaggacccgc aacctacccc actggcctgg cagcgaatgc gggtaaatca ggcgcataac
    17461 actctgtata actcattgaa tcaggcgatg caggaaccag cgttcaacag ccattatctg
    17521 gcagatatga aactgtgggt aacgcacagc cagtttattg ttgagcatat taatgccatg
    17581 accacgctgg cgcgggaaca ccgggcattg ccacctgaac tggcacaaga gtatttacag
    17641 tcttgtgaaa tcgccattca gcgttgtcag cagcggctgg aatatgacga accggggagt
    17701 tctggcgatg ccaatatcat ggatgcgccg gagatgcagc cgcacgaagg cgcggcaggt
    17761 acgctggagc agcatttaca gcgggttatt ggtcatctga acaccatgca caccatttcg
    17821 tcgatggcat ggcgtcagcg accgcatcac gggatttggc tgagtcgcaa gttgcgggat
    17881 tcgaaggcgt aatgcaggct aaaccatcgg ataaggcatt cacgccgcat ccgacatctt
    17941 ttgcctgatg cttcgtattt acgccccaat caccttagcc accgcgtggg cgaaacgttg
    18001 catcccttca tcgatatccg catcttccac caccagcgac ggtgcaaaac gcatcacatc
    18061 cggtccggca ttcagcacca ttacgccagc ctctgcgccc gcatacagga aatcacgcgc
    18121 ccgacctttg aactgtggct taagctccgc gccaatcaac agccccatac cgcgaatatc
    18181 gctaaacaca tcgtactgct gatcgatctt ctgcaaatgg tcaacaaaac gctggcgttt
    18241 cgcctgaatg ccttccagca cttcaggggt attgatgata tcaaacgccg cgcccgctac
    18301 tgcacaggcc agaggattac cgccgtaggt ggaaccgtga gaaccaggat gaaacgcaga
    18361 agcaatttcc gccgtggtca gcatggcgct aatcgggaag ccgccgccta acgctttcgc
    18421 agaggtcaga atatccggcg tcacaccgta gtgcatgtaa gcaaacaaat cgccagtccg
    18481 ccccatcccg cactgcactt catcaaacac caataatgcc tgatgttgat cgcacagctc
    18541 gcgcaagccc tgcaaaaact ctggcgtcgc agccgtcaca ccgccctcgc cctggatcgg
    18601 ctcaaccacc accgcacagg tgtgatcatc catcaccgct ttcactgcgt ggagatcgtt
    18661 aaagggaacg tggatgatgt ctgccggttt tggcccaaag ccgtcggaat attttggctg
    18721 cccgcccacc gagacggtaa acagcgagcg accatgaaaa gcgttatgga aggcaataat
    18781 tttggttttg aacgggctat gacgcacaca ggcataatgg cgtgccagtt taaaggcggt
    18841 ttcgttagct tccgtgccgg agttcataaa caccacgcgt tcggcaaacg tcgcctcaat
    18901 cagtttgcgc ccaagacgca gcgccggttc attggtgaaa acgttactga tatgccacag
    18961 agtttcgccc tgggttttta acgcattcac cagcgcagga tggcaatggc ccaacgccgt
    19021 aactgcaatg ccacccgcga aatcgacata ctccttgcct tgctgatccc agattcggct
    19081 gccctgacct tttaccggaa tgaactctgc cggagcataa atcggcagga tcacttcatc
    19141 gaaagtcgcc cgtgtaattg ctgtttgttc aattgccatc tcatgatcac cctgttacgc
    19201 ataaataaat gtgaaattat aatcacaaaa tatgcataaa aaatcactga atggcaatca
    19261 gaaatcagcg atgcagaaaa ttagccagca gttgatgtcc ttgttcgcta agaatacttt
    19321 ctggatggaa ttgcacacct tccagatccc actggcgatg gcgaatcccc ataatctcgc
    19381 gggtttcgct ccaggccgtc acgtcaaagc acgctggtaa tgagtcaggt tccaccacca
    19441 gcgaatggta gcgtgtcacg gtgagtggat ttgccagccc ccgaaatacg ccctcaccgt
    19501 tatgtgtaat cggcgaggtt ttgccgtgca taacctttgc ggcgcgcaca actttaccgc
    19561 caaatgcctg cgccattgcc tgatgaccga ggcagacgcc aagaatcggc aagcgcccgg
    19621 catagtggcg aataacgtca agggagatcc cggcttcatc tggcgtacag gggccaggtg
    19681 agatgacaat tttttgtggt ttaagggcgt cgatatccgc cagcgtcaac gcatcgttgc
    19741 gcttaaccag cacatccgcc cccagttcac aaaagtactg gtagaggttc caggtaaaag
    19801 aatcgtagtt atctataagc aggatcatgg cggctccggt acgaaagaac cgcgctattt
    19861 tactcagatt ccccggcttc gcttaccact ttgctaaata tcatctgcag cgcggtgaga
    19921 tcccccattg ctccactctg atttgcctga ttccaggcct ctttttcgat accctgccag
    19981 ctcagttgat atccggcatg aatcgccagt tgctcgaaga agatccgctg tgccagacca
    20041 cttcccaccc ggaagggatg cagcacgttg atttcacaat agtaatgcgc cagccgctcg
    20101 acgaacttcg ctttctccag gccaaccaga taaccttctt cctccagatc ctgcatcagg
    20161 gcattgccct ctttttcgat ataagcaaag tggcagaacg gcgtatcgcc ctgataaata
    20221 tcaacttcac gcagttgccc tgcccagtcg aaaatatcct ggtacagctg gcgatggata
    20281 gtgcgcaaat gcggtaaacc gcgcaccagc ggaccaagct caatggtcgc agcacgcagc
    20341 gccgtcattt cgtaagcggc ctgttccagc cgctgctgct ggcggatgtt cagccggtta
    20401 cgcatgatat caaggccagg ataaagatac ggatcgcgcc cttcgccgaa tttatcgctc
    20461 atagtgactc ctcagctctt caaggcgcgc taaagcctct gcggcagtaa gagtgactaa
    20521 aggcatctcg acgccttcaa gacggcgact ggcctgaaaa ttacgattac gctgaagctc
    20581 ccagagacgg gacttttgct tatcggtgag tttcttcact tgatgcctcc ctgaacgtgt
    20641 ccatttgcca caagtataag cggcaaatcc gggttacgcc gggagagcaa aagcgcgggc
    20701 aagattgccc gcgcgagaaa tcattacggc aggactttag cggaaaggat aactaccggt
    20761 tttgacggca cattctggta cggaccaacg tcatgagtcg gcacctggga aatcttatcg
    20821 gcaacgtcca tgcctttcac cactttacca aataccgcgt aaccgaaatc acgctgacca
    20881 tggtcaagga aggcgttatc ggcaacgttg ataaagaact ggctggtggc gctgtctttg
    20941 tcggcggtac gcgccatcgc gatggtacca cgcgtgttgc gcaggccatt atcggcttca
    21001 tttttgattg gcgggtttgg ttttttctgc tgcatctgct cggtgaaacc gccgccctga
    21061 atcataaagc caggaatgac gcggtgaaag gtagtgttgt tataaaaacc gctgttcaca
    21121 taatcgacaa agttctgcac agacactggc gctttttgtt tatccagctc cagttcgatg
    21181 ttaccagctg aggttgtcaa caatacgtgc gggtcccctt tcgctgccat tgctgcggga
    21241 gaaagagcag aaagagcgaa aacagcagcc atcgccgcca gggtcgattt gaacatgaga
    21301 tttccttaac aaacagagca gaaaaaaagc aagtgaagag attctaaata gccttcaaga
    21361 acaaggccat ccctttacct aattttacgt atctgaaata tatgtaacct gacgatcact
    21421 ttttattccg tgatcaaaat cacctcttaa aatgcaattt agcaaccgat tgcaataaaa
    21481 catttaaaca gatcacaaaa tcacctaaaa tcgcccgctc gcggcatatc ccgctatgcc
    21541 attttatttt tgaacgcagg ccaatcatga ctaacagcaa tcgcatcaag ctcacatgga
    21601 ttagctttct ctcctacgca ctgactggtg cgttggttat tgtcaccggg atggtgatgg
    21661 gaaatatcgc cgattatttc aatctgcctg tttccagtat gagtaacacc ttcaccttcc
    21721 tcaacgccgg cattttaatc tctatcttcc tcaacgcctg gctgatggaa atcgtcccgt
    21781 tgaaaacgca gttacgtttt ggctttctcc tgatggtgct ggcggttgcc ggtttgatgt
    21841 tcagccacag cctggcgctg ttctcggcgg cgatgttcat tctcggggtg gtcagcggca
    21901 tcaccatgtc gattggtaca ttcctggtaa cacaaatgta tgaagggcgt cagcgcggtt
    21961 cccgcctgtt atttaccgac tccttcttca gtatggctgg gatgattttc ccaatgatcg
    22021 ccgcgtttct actggcgcgc agcattgagt ggtactgggt ttatgcctgc atcgggctgg
    22081 tgtatgtcgc tatttttatt ctgaccttcg gctgtgagtt cccggcgctg ggcaaacatg
    22141 cgccaaaaac ggatgctccg gtagagaaag aaaagtgggg gatcggcgta ctgtttctct
    22201 ctgttgcggc gctgtgctac atccttggtc agttaggttt tatctcctgg gtgcctgagt
    22261 atgccaaagg cctgggcatg agcctgaacg acgcgggcac gctggtgagt aacttctgga
    22321 tgtcatacat ggtcggcatg tgggcgttca gctttattct tcgcttcttt gatttgcaac
    22381 gtattctgac cgtactggct ggtctggctg cgattctgat gtacgtcttt aacaccggaa
    22441 caccagcaca tatggcgtgg tcaattctcg ctctgggctt cttctccagc gcgatctata
    22501 ccaccatcat caccctgggt tcacagcaga ccaaagtacc gtcgccaaaa ctggttaact
    22561 ttgtcctgac ctgcggaacc atcggtacta tgttgacctt tgtggttacc ggcccgattg
    22621 ttgaacatag cggtccgcag gcggcactgc ttacagcaaa cggtctgtac gctgtcgtct
    22681 ttgtgatgtg cttcctgtta ggtttcgtca gccgtcaccg tcagcataac accctgacct
    22741 ctcattaatt gctaatgccg gacggcacta tcgtcgtccg gccttttcct ctcttccccc
    22801 gctacgtgca tctatttcta taaacccgtt cattttgtcc attttttgca caaacatgaa
    22861 atgtcagaca attccgtgac ttaagaaaat ttatacaaat cagcaatata ccccttaagg
    22921 agtatataaa ggtgaatttg atttacatca ataagcgggg ttgctgaatc gttaaggtag
    22981 gcggtaatag aaaagaaatc gaggcaaaaa tgagcaaagt cagactcgca attatcggta
    23041 acggtatggt cggccatcgc tttatcgaag atcttcttga taaatctgat gcggccaact
    23101 ttgatattac cgttttctgt gaagaaccgc gcatcgctta tgaccgcgta cacctctcgt
    23161 cttacttctc tcaccacacc gccgaagagc tgtcgctggt gcgcgaaggc ttctacgaga
    23221 aacacggcat caaagttctg gtcggcgaac gtgctatcac catcaaccgt caggagaagg
    23281 tgattcactc cagcgccggg cgcaccgttt tttatgacaa gctgatcatg gcgaccggtt
    23341 cctacccgtg gatcccgcca atcaaaggtt ctgatactca ggactgcttt gtctatcgca
    23401 ccattgaaga cctcaacgcc attgaatcct gtgcccgtcg cagcaaacgc ggtgccgttg
    23461 ttggtggcgg cctgttaggt ctggaagccg ctggcgcgct gaaaaactta ggtattgaaa
    23521 cccacgttat cgaatttgcc cctatgctga tggcggaaca gcttgatcag atgggtggcg
    23581 agcagctgcg tcgcaaaatc gaaagtatgg gcgtgcgcgt tcacaccagc aaaaacaccc
    23641 ttgagattgt gcaggaaggt gtcgaagcgc gtaaaaccat gcgttttgcc gacggcagcg
    23701 aactggaagt cgactttatc gtcttctcta ccggtatccg tccgcgcgat aagctggcaa
    23761 cccagtgtgg tctggacgta gctccgcgtg ggggtattgt cattaatgat tcctgccaga
    23821 cttccgatcc ggatatctac gccatcggtg aatgcgcaag ctggaacaac cgtgtatttg
    23881 gtctggtagc accaggctac aaaatggcgc aggtcgccgt tgaccatatt ctcggtagcg
    23941 aaaacgcctt tgaaggtgct gaccttagcg ccaagctgaa actgctgggc gtagacgtag
    24001 gcggtattgg tgatgcgcac ggtcgcacgc ctggcgcacg tagctacgtt tacctcgacg
    24061 aaagcaaaga gatctacaaa cgccttattg tcagcgaaga caacaaaacc ctgctcggtg
    24121 cggtactggt gggcgatacc agcgactacg gcaacctgct gcaactggtg ctgaatgcta
    24181 tcgagctgcc ggaaaacccg gattctctga ttctgccggc gcactcgggt agcggtaagc
    24241 cgtctatcgg tgttgataaa ctgccggaca gcgcgcaaat ctgctcctgc ttcgacgtca
    24301 ccaaaggtga tctgattgct gccatcaaca aaggctgcca caccgttgcg gcgctgaaag
    24361 ccgaaaccaa agcgggtact ggctgcggtg gctgtatccc gctggtcact caggtactga
    24421 acgcggaact ggcgaaacag ggcatcgaag ttaacaacaa cctgtgcgaa cactttgctt
    24481 attcgcgtca ggaactgttc catttgatcc gcgttgaagg cattaaaacc ttcgaagaac
    24541 tgctggcgaa acacggcaaa ggttacggtt gtgaagtttg taaaccgacc gtcggttcgc
    24601 tgctggcctc ctgctggaac gaatacattc tgaagccgga acatactccg ctgcaggatt
    24661 caaacgacaa cttcctcgct aacatccaga aagacggcac ctactcggtg atcccgcgtt
    24721 ctccgggcgg tgaaatcacc ccggaagggc tgatggcagt aggtcgtatc gcgcgtgaat
    24781 ttaatctcta caccaaaatc accggctctc agcgcctggc gatgtttggc gcacagaaag
    24841 acgatctgcc ggagatctgg cgtcagctga ttgaagctgg cttcgaaacc ggtcatgcct
    24901 atgcgaaagc actacgtatg gcgaaaacct gcgtgggtag cacctggtgc cgctacggcg
    24961 ttggcgacag cgtcggcctc ggcgtggaac tggaaaaccg ctacaaaggc atccgtacgc
    25021 cgcacaaaat gaagttcggt gtctccggct gtacccgtga atgttcagaa gctcagggta
    25081 aagacgtggg tattatcgcc actgaaaaag gctggaacct gtatgtttgc ggtaacggcg
    25141 gcatgaaacc gcgtcatgcg gatctgctgg cggcggatat cgatcgcgaa acgctgatca
    25201 aatatctcga ccgcttcatg atgttctaca tccgtaccgc cgacaaactg acgcgtaccg
    25261 caccgtggtt agaaaacctc gaaggcggca ttgattacct gaaagcggtg atcattgacg
    25321 acaaactggg gctgaacgca catctggaag aagagatggc gcgcctgcgt gaagcggtag
    25381 tgtgtgagtg gactgaaacg gtcaatacgc cgtctgcgca gactcgcttc aaacacttca
    25441 tcaacagcga caagcgtgac ccgaacgtgc agatggtgcc agagcgcgaa cagcaccgtc
    25501 cggcaacgcc gtatgaacgt atcccggtaa ctctggtgga ggacaacgca tgaaccagtg
    25561 gaaagacatc tgcaaaatcg atgacatcct gcctgaaacc ggcgtctgcg cgctgttagg
    25621 tgacgagcag gtagcaattt tccgcccgta tcacagcgac caggtgtttg cgatcagcaa
    25681 cattgatccg ttcttcgagt ccagcgtgct gtcacgcggg ctgattgcgg aacaccaggg
    25741 cgagctgtgg gtcgccagcc cgctgaaaaa acagcgtttt cgcttaagtg atggcttgtg
    25801 catggaagac gaacagtttt ccgtcaaaca ttacgaagca cgagtgaaag acggcgtggt
    25861 gcagctgcgc ggttaatgtt ttaacgggag gcgcaatgcc tccccttttt gcatggtcct
    25921 gtaatgacct tcggtatatt gcaggacatt ttttaaactt tttgttttat ttttttgttt
    25981 ttatttttta aaggataatc aaatgtttac agacactatt aataagtgtg cggctaacgc
    26041 tgcgcgcatt gcacgcctgt cggcaaataa cccgctcggc ttttgggtca gctccgccat
    26101 ggcgggcgcg tatgtgggtc ttgggatcat cttgattttc acgctcggta atttgctcga
    26161 cccgtccgta cgtccgctgg tgatgggcgc gacctttggt atcgccttaa cgctggtgat
    26221 tatcgccggt tctgaactgt tcaccggaca caccatgttc ctcacctttg gggtaaaagc
    26281 gggcagcatc agccacgggc aaatgtgggc aatcctgccg caaacctggc tgggtaacct
    26341 ggtcggttcc gtcttcgttg ccatgctcta tagctggggt ggcggtagcc tgctgccggt
    26401 agataccagc atcgttcact ccgtcgcgct ggctaaaacc actgcaccgg caatggtact
    26461 gttcttcaaa ggtgcattgt gtaactggct ggtttgtctg gcaatctgga tggcgctgcg
    26521 cactgaaggg gcggcgaaat ttatcgctat ctggtggtgt ctgctggcat ttatcgcgtc
    26581 cggctacgag cactccatcg ctaacatgac gctgttcgcg ctctcctggt tcggcaacca
    26641 cagcgaagcc tacacgctgg cgggtattgg tcataacctg ctgtgggtga cgctgggtaa
    26701 tactttatca ggtgccgtat tcatgggatt gggttattgg tatgctacgc cgaaagcgaa
    26761 tcgtccggtt gcggacaaat ttaatcaaac tgaaacggct gccggttaat tactaagggg
    26821 tttttacgtg gatcatttgc ctatattttg ccaattacgc gatcgcgact gtctgattgt
    26881 cggcggtggt gatgtcgcgg aacgcaaagc aaggttgctg ttagacgcag gcgctcgctt
    26941 aacggtgaat gcattagcgt ttattccaca gttcaccgca tgggcagatg caggcatgtt
    27001 aaccctcgtc gaagggccat ttgatgaaag ccttctcgac acctgctggc tggcgattgc
    27061 agcgacggat gatgacgcgc ttaaccagcg cgtcagcgaa gccgctgaag ctcgtcgcat
    27121 cttctgtaac gtggtcgatg cgccgaaagc tgccagcttc attatgccgt cgattattga
    27181 ccgctcaccg ctgatggtgg cggtttcctc tggcggtact tctccggttc tggcgcgcct
    27241 gttgcgcgaa aaactcgaat cactgctgcc gctgcatctg ggccaggtag cgaaatacgc
    27301 cgggcagtta cgcggtcggg taaaacaaca gttcgccacg atgggtgaac gccgccgctt
    27361 ctgggaaaaa ctgttcgtta acgaccgtct ggcgcagtcg ctggcgaaca acgatcagaa
    27421 agccattact gaaaccaccg aacagttaat caacgaaccg ctcgaccatc gcggtgaagt
    27481 ggtgctggtt ggtgcaggtc cgggcgatgc cgggctgctg acgctgaaag gactgcaaca
    27541 aattcagcag gcagatgtgg tggtctacga ccgtctggtt tctgacgata ttatgaatct
    27601 ggtacgccgc gatgctgatc gcgttttcgt cggcaaacgc gcgggatacc actgtgtacc
    27661 gcaggaagag attaaccaga tcctgctgcg ggaagcgcaa aaaggcaaac gcgtggtgcg
    27721 gctgaaaggt ggcgatccgt ttatttttgg ccgtggtggc gaagagctgg aaacactgtg
    27781 caacgcgggt attccgttct cggtggttcc gggtattacc gcagcttctg gttgctctgc
    27841 ctattcgggt attccgctca cgcatcgcga ttatgcccag agcgtgcgct taattaccgg
    27901 acacttaaaa accggtggcg agctggactg ggaaaacctg gcggcagaaa aacagacgct
    27961 ggtgttctat atggggctga atcaggctgc gactattcag caaaagctga ttgaacacgg
    28021 tatgcctggc gaaatgccgg tagcaattgt cgaaaacgga acagcagtca cgcagcgcgt
    28081 gattgacggt acgctcacac aactgggcga actggcgcag caaatgaaca gtccatcgct
    28141 aattattatt ggtcgggttg ttggcctgcg cgataaactg aactggttct ccaaccatta
    28201 atttaatcag ggccagagaa ttctggcctt tttcgtttac aactctcttt atatattcag
    28261 cagataaaaa tataactcat taacaaaaat catttgtttt tgccccgtta tattcaccgt
    28321 tacagcgact tacaaaatta agtcattcac tcactgacgc cgattaaata ttcctgtatc
    28381 gttcttaatg agc
//
LOCUS       DAPGUL010000056        27364 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.056, whole genome shotgun sequence.
ACCESSION   DAPGUL010000056 DAPGUL010000000
VERSION     DAPGUL010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 27364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27364
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.056"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            195..2618
                     /gene="pgaA"
                     /locus_tag="RHX21_002585"
     CDS             195..2618
                     /gene="pgaA"
                     /locus_tag="RHX21_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6 N-acetyl-D-glucosamine export
                     porin PgaA"
                     /protein_id="HDV1987746.1"
                     /translation="MYSSSRKRCPKTKWALKLLTAAFLAASPAAKSAVNNAYDALIIE
                     ARKGNTQPALSWFALKSALSNNQIADWLQIALWAGQDKQVITVYNRYRHQQLPARGYA
                     AVAVAYRNLQQWQNSLTLWQKALSLEPQNKDYQRGQILTLADAGHYDTALVKLKQLNS
                     GAPDKANLLAEAYIYKLAGRHQDELRAMTESLPENASTQQYPTEYVQALRNNQLAAAI
                     DDANLTPDIRADIHAELVRLSFMPTRSESERYAIADRALAQYAALEILWHDNPDRTAQ
                     YQRIQVDHLGALLTRDRYKDVISHYQRLKKTGQIIPPWGQYWVASAYLKDHQPKKAQS
                     IMTELFYHKETIAPDLSDEELADLFYSHLESENYPGALTVTQHTINTSPPFLRLMGTP
                     TSIPNDTWLQGHSFLSTVAKYSNDLPQAEMTARELAYNAPGNQGLRIDYASVLQARGW
                     PRAAENELKKAEVIEPRNINLEVEQAWTALTLQEWQQAAVLTHDVVEREPQDPGVVRL
                     KRAVDVHNLAELRIAGSTGIDAEGPDSGKHDVDLTTIVYSPPLKDNWRGFAGFGYADG
                     QFSEGKGIVRDWLAGVEWRSRNIWLEAEYAERVFNHEHKPGARLSGWYDFNDNWRIGS
                     QLERLSHRVPLRAMKNGVTGNSAQAYVRWYQNERRKYGVSWAFTDFSDSNQRHEVSLE
                     GQERIWSSPYLIVDFLPSLYYEQNTEHDTPYYNPIKTFDIVPAFEASHLLWRSYENSW
                     EQIFSAGVGASWQKHYGTDVVTQLGYGQRISWNDVIDAGATLRWEKRPYDGDREHNLY
                     VEFDMTFRF"
     gene            2627..4645
                     /gene="pgaB"
                     /locus_tag="RHX21_002586"
     CDS             2627..4645
                     /gene="pgaB"
                     /locus_tag="RHX21_002586"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6-N-acetyl-D-glucosamine
                     N-deacetylase PgaB"
                     /protein_id="HDV1987747.1"
                     /translation="MLRNGNKYLLMLVSIIMLTACISQSRTSFIPPQDRESLLAEQPW
                     PHNGFVAISWHNVEDEAADQRFMSVRTSALREQFAWLRENGYQPVSIAQIREAHRGGK
                     PLPEKAVVLTFDDGYQSFYTRVFPILQAFQWPAVWAPVGSWVDTPADKQVKFGDELVD
                     REYFATWQQVREVARSRLVELASHTWNSHYGIQANATGSLLPVYVNRAYFTDHARYET
                     AAEYRERIRLDAVKMTEYLRTKVEVNPHVFVWPYGEANGIAIEELKKLGYDMFFTLES
                     GLANASQLDSIPRVLIANNPSLKEFAQQIITVQEKSPQRIMHIDLDYVYDENLQQMDR
                     NIDVLIQRVKDMQISTVYLQAFADPDGDGLVKEVWFPNRLLPMKADIFSRVAWQLRTR
                     SGVNIYAWMPVLSWDLDPTLTRVKYLPTGEKKTQIHPEQYHRLSPFDDRVRAQVGMLY
                     EDLAGHAAFDGILFHDDALLSDYEDASAPAITAYQQAGFSGSLSEIRQNPEQFKQWAR
                     FKSRALTDFTLELSARVKAIRGPHIKTARNIFALPVIQPESEAWFAQNYADFLKSYDW
                     TAIMAMPYLEGVAEKSADQWLIQLTNQIKNIPQAKDKSILELQAQNWQKNGQHQAISS
                     QQLAHWMSLLQLNGVKNYGYYPDNFLHNQPEIDLIRPEFSTAWYPKND"
     gene            4638..5963
                     /gene="pgaC"
                     /locus_tag="RHX21_002587"
     CDS             4638..5963
                     /gene="pgaC"
                     /locus_tag="RHX21_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6 N-acetyl-D-glucosamine synthase"
                     /protein_id="HDV1987748.1"
                     /translation="MINRIVSFFILCLVLCIPLCVAYFHSGELMMRFVFFWPFFMSIM
                     WIVGGVYFWVYRERHWPWGENAPAPQLKDNPSISIIIPCFNEEKNVEETIHAALAQRY
                     ENIEVIAVNDGSTDKTRAILDRMAAQIPHLRVIHLAQNQGKAIALKTGAAAAKSEYLV
                     CIDGDALLDRDAAAYIVEPMLYNPRVGAVTGNPRIRTRSTLVGKIQVGEYSSIIGLIK
                     RTQRIYGNVFTVSGVIAAFRRSALAEVGYWSDDMITEDIDISWKLQLNQWTIFYEPRA
                     LCWILMPETLKGLWKQRLRWAQGGAEVFLKNMTRLWRKENFRMWPLFFEYCLTTIWAF
                     TCLVGFIIYAVQLAGVPLNIELTHIAATHTAGILLCTLCLLQFIVSLMIENRYEHNLT
                     SSLFWIIWFPVIFWMLSLATTLVSFTRVMLMPKKQRARWVSPDRGILRG"
     gene            5965..6378
                     /gene="pgaD"
                     /locus_tag="RHX21_002588"
     CDS             5965..6378
                     /gene="pgaD"
                     /locus_tag="RHX21_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6-N-acetyl-D-glucosamine
                     biosynthesis protein PgaD"
                     /protein_id="HDV1987749.1"
                     /translation="MNNLIITTRQSPVRLLVDYVATTILWTLFALFIFLFAMDLLTGY
                     YWQSEARSRLQFYFLLAVANAVVLIVWALYNKLRFQKQQHHAAYQYTPQEYAESLAIP
                     DELYQQLQKSHRMSVHFTSQGQIKMVVSEKALVRA"
     gene            complement(6428..7216)
                     /gene="phoH"
                     /locus_tag="RHX21_002589"
     CDS             complement(6428..7216)
                     /gene="phoH"
                     /locus_tag="RHX21_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PhoH"
                     /protein_id="HDV1987750.1"
                     /translation="MGRQKAVIKARREAKRVLRRDSRSHKQREEESVTSLVQMGGVEA
                     IGMARDSRDTSPILARNEAQLHYLKAIESKQLIFATGEAGCGKTWISAAKAAEALIHK
                     DVDRIIVTRPVLQADEDLGFLPGDIAEKFAPYFRPVYDVLVRRLGASFMQYCLRPEIG
                     KVEIAPFAYMRGRTFENAVVILDEAQNVTAAQMKMFLTRLGENVTVIVNGDITQCDLP
                     RGVCSGLSDALERFEEDEMVGIVRFGKEDCVRSALCQRTLHAYS"
     gene            complement(7835..9106)
                     /gene="efeB"
                     /locus_tag="RHX21_002590"
     CDS             complement(7835..9106)
                     /gene="efeB"
                     /locus_tag="RHX21_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deferrochelatase/peroxidase EfeB"
                     /protein_id="HDV1987751.1"
                     /translation="MQYEDKNGVNEPSRRRLLKGIGALALAGSCPVAHAQKTQSAPGT
                     LSPDARNEKQPFYGEHQAGILTPQQAAMMLVAFDVLASDKPDLERLFRLLTQRFAFLT
                     QGGAAPETPNPRLPPLDSGILGGYIAPDNLTITLSVGHSLFDERFGLAPQMPKKLQKM
                     TRFPNDSLDAALCHGDVLLQICANTQDTVIHALRDIIKHTPDLLSVRWKREGFISDHA
                     ARSKGKETPINLLGFKDGTANPDSQNDKLMQKVVWVTADQQEPAWTIGGSYQAVRLIQ
                     FRVEFWDRTPLKEQQTIFGRDKQTGAPLGMQHEHDVPDYASDPEGKVIALDSHIRLAN
                     PRTAESESSLMLRRGYSYSLGVTNSGQLDMGLLFVCYQHDLEKGFLTVQKRLNGEALE
                     EYVKPIGGGYFFALPGVKDANDYLGSALLRV"
     gene            complement(9112..10239)
                     /gene="efeO"
                     /locus_tag="RHX21_002591"
     CDS             complement(9112..10239)
                     /gene="efeO"
                     /locus_tag="RHX21_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron uptake system protein EfeO"
                     /protein_id="HDV1987752.1"
                     /translation="MTINFRRNALQLSVAALFSSAFMANAANVPQVKVTVTDKQCEPM
                     TITVNAGKTQFIIQNHSQKALEWEILKGVMVVEERENIAPGFSQKMTANLQPGEYDMT
                     CGLLTNPKGKLIVKGEATADAAQSDALLSLGGAITAYKAYVMAETTQLVTDTKAFTDA
                     IKAGDIEKAKALYAPTRQHYERIEPIAELFSDLDGSIDAREDDYEQKAADPKFTGFHR
                     LEKALFGDNTTKGMDQYADQLYTDVVDLQKRISELAFPPSKVVGGAAGLIEEVAASKI
                     SGEEDRYSHTDLWDFQANVEGSQKIVDLLRPQLQKANPELLAKVDANFKKVDTILAKY
                     RTKDGFETYDKLTDADRNALKGPITALAEDLAQLRGVLGLD"
     gene            complement(10297..11127)
                     /locus_tag="RHX21_002592"
     CDS             complement(10297..11127)
                     /locus_tag="RHX21_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FTR1 family protein"
                     /protein_id="HDV1987753.1"
                     /translation="MFVPFLIMLREGLEAALIVSLIASYLKRTQRGRWIGVMWIGVLL
                     AAALCLGLGIFINETTGEFPQKEQELFEGIVAVIAVVILTWMVFWMRKVSRNVKVQLE
                     QAVDSALQRGNHHGWALVMMVFFAVAREGLESVFFLLAAFQQDVGIWPPLGAMLGLAT
                     AVVLGFLLYWGGIRLNLGAFFKWTSLFILFVAAGLAAGAIRAFHEAGLWNHFQEIAFD
                     MSAVLSTHSLFGTLMEGIFGYQEAPSVSEVAVWFIYLIPALVAFALPPRAGATASRSA
                     "
     gene            complement(11669..13177)
                     /gene="putP"
                     /locus_tag="RHX21_002593"
     CDS             complement(11669..13177)
                     /gene="putP"
                     /locus_tag="RHX21_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/proline symporter PutP"
                     /protein_id="HDV1987754.1"
                     /translation="MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGP
                     FVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTE
                     YNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSY
                     ETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGFGDSLEV
                     IKQKSIENVDMLKGLNFVAIISLMGWGLGYFGQPHILARFMAADSHHSIVHARRISMT
                     WMILCLAGAVAVGFFGIAYFNEHPAVAGAVNQNAERVFIELAQILFNPWIAGILLSAI
                     LAAVMSTLSCQLLVCSSAITEDLYKAFLRKHASQKELVWVGRVMVLVVALVAIALAAN
                     PENRVLGLVSYAWAGFGAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFGWL
                     GLYEIIPGFIFGSIGIVVFSLLGKAPSAAMQKRFAEADAHYHSAPPSRLQES"
     gene            complement(13336..13545)
                     /locus_tag="RHX21_002594"
     CDS             complement(13336..13545)
                     /locus_tag="RHX21_002594"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987755.1"
                     /translation="MMLQLCATMLNVTCVASLKMNEMLIKEIDMTGIKKITQTFSLRQ
                     LTFLKGATAKNVRECNLMKNSVAEH"
     gene            13600..17562
                     /gene="putA"
                     /locus_tag="RHX21_002595"
     CDS             13600..17562
                     /gene="putA"
                     /locus_tag="RHX21_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trifunctional transcriptional regulator/proline
                     dehydrogenase/L-glutamate gamma-semialdehyde
                     dehydrogenase"
                     /protein_id="HDV1987756.1"
                     /translation="MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQL
                     ENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRP
                     ETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQ
                     EGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGK
                     LVSTHNEASLSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLE
                     EKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALH
                     PRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLEKLCFEPE
                     LAGWNGIGFVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGL
                     EGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQY
                     EFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLENGANTSF
                     VNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDL
                     ANEHRLASLSSALLNSALQKWQALPMLEQPVAAGEMSPVINPAEPKDIVGFVREATPR
                     EVEQALESAVNNAPIWFATPPVERAAILHRAAVLMESQMQQLIGILVREAGKTFSNAI
                     AEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNS
                     VLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGQGETVGAQLTGDDRVRGVMFTGS
                     TEVATLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVVDVLASAFDSAG
                     QRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIERHI
                     QTMRSKGRPVFQAVRENSEDAREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYN
                     RNQLPELIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPF
                     GGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAEYPVDAQLKAALTQPLNAL
                     REWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDEQDAL
                     TQLAAVLAVGSQVLWPDDALHRQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDS
                     DQLRALCEAVAARDGAIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
                     "
     gene            complement(17602..18240)
                     /gene="rutR"
                     /locus_tag="RHX21_002596"
     CDS             complement(17602..18240)
                     /gene="rutR"
                     /locus_tag="RHX21_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator RutR"
                     /protein_id="HDV1987757.1"
                     /translation="MTQGAVKTTGKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQI
                     AELAGVSKTNLLYYFPSKEALYIAVLRQILDIWLAPLKAFREDFAPLAAIKEYIRLKL
                     EVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKALIDEKSALIAGWVKSGKLAPIDPQ
                     HLIFMIWASTQHYADFAPQVEAVTGATLRDEIFFNQTVENVQRIIIEGIRPR"
     gene            18528..19619
                     /gene="rutA"
                     /locus_tag="RHX21_002597"
     CDS             18528..19619
                     /gene="rutA"
                     /locus_tag="RHX21_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309285.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein A"
                     /protein_id="HDV1987758.1"
                     /translation="MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDF
                     ALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAA
                     TIDSISGGRFGVNLVTGWQKPEYEQMGIWPGDDYFSRRYDYLTEYVQVLRDLWGTGKS
                     DFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSAQYADFNFCFGKGVNTPTAFA
                     PTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQ
                     KDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVASVPGAEGVLLTFDDF
                     LSGIETFGERIQPLMQCRAHLPALTQEVA"
     gene            19619..20311
                     /gene="rutB"
                     /locus_tag="RHX21_002598"
     CDS             19619..20311
                     /gene="rutB"
                     /locus_tag="RHX21_002598"
                     /EC_number="3.5.1.110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415531.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxyureidoacrylate/ureidoacrylate
                     amidohydrolase RutB"
                     /protein_id="HDV1987759.1"
                     /translation="MTTLTARPEAITFDPQQSALIVVDMQNAYATPGGYLDLAGFDVS
                     TTRPVIANIQTAVTAARAAGMLIIWFQNGWDEQYVEAGGPGSPNFHKSNALKTMRKQP
                     QLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTG
                     IATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFC
                     DALSPTSFARIA"
     gene            20323..20709
                     /gene="rutC"
                     /locus_tag="RHX21_002599"
     CDS             20323..20709
                     /gene="rutC"
                     /locus_tag="RHX21_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein C"
                     /protein_id="HDV1987760.1"
                     /translation="MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLF
                     ADDPKAQTRHVLETIRKVIETAGGTMADVTFNSIFITDWKNYAAINEIYAEFFPGDKP
                     ARFCIQCGLVKPDALVEIATIAHIAK"
     gene            20717..21517
                     /gene="rutD"
                     /locus_tag="RHX21_002600"
     CDS             20717..21517
                     /gene="rutD"
                     /locus_tag="RHX21_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein D"
                     /protein_id="HDV1987761.1"
                     /translation="MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVC
                     YDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALDYP
                     ASVTVLISVNGWLRINAHTRRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPR
                     LEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPSACSS
                     ELHAALPDSQKMVMRYGGHACNVTDPETFNALLLNGLASLLHHREAAL"
     gene            21527..22117
                     /locus_tag="RHX21_002601"
     CDS             21527..22117
                     /locus_tag="RHX21_002601"
                     /EC_number="1.1.1.298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonic semialdehyde reductase"
                     /protein_id="HDV1987762.1"
                     /translation="MNEAVSPGALSTLFTDARTHNGWRETPVSDETLRELYALMKWGP
                     TSANCSPARIVFIRTVEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPLLFP
                     HGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQYVDDAFFA
                     GSTLKSNLLINIGYGDSSKLYARLPRLSFEEACGLL"
     gene            22128..22622
                     /gene="rutF"
                     /locus_tag="RHX21_002602"
     CDS             22128..22622
                     /gene="rutF"
                     /locus_tag="RHX21_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309280.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization flavin reductase protein
                     F"
                     /protein_id="HDV1987763.1"
                     /translation="MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTD
                     TPPTLLVCLNRGASVWPVFNENRTLCVNTLSAGQEPLSNLFGGKTPMEHRFAAARWQT
                     GVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALM
                     RPAC"
     gene            22643..23971
                     /gene="rutG"
                     /locus_tag="RHX21_002603"
     CDS             22643..23971
                     /gene="rutG"
                     /locus_tag="RHX21_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization transport protein G"
                     /protein_id="HDV1987764.1"
                     /translation="MAMFGFPHWQLKSTSTESGVVAPYERLPFAQTAVMGVQHAVAMF
                     GATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNG
                     QGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAP
                     IAVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLG
                     LGKAVDFTLVSHAAWFGLPHFSTPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGR
                     NMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAML
                     LGFSPKFGALIHTIPAPVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTL
                     VLGAGDFALTLGGFTLGGIGTATFGAILLNALLSRRLVDVPPPEVVHQEP"
     gene            complement(24054..24227)
                     /locus_tag="RHX21_002604"
     CDS             complement(24054..24227)
                     /locus_tag="RHX21_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415525.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein"
                     /protein_id="HDV1987765.1"
                     /translation="MANHRGGSGNFAEDRERASEAGKKGGQHSGGNFKNDPQRASEAG
                     KKGGKSSHGKSDN"
     gene            24600..25196
                     /gene="wrbA"
                     /locus_tag="RHX21_002605"
     CDS             24600..25196
                     /gene="wrbA"
                     /locus_tag="RHX21_002605"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H:quinone oxidoreductase"
                     /protein_id="HDV1987766.1"
                     /translation="MAKVLVLYYSMYGHIETMARAVAEGASKVDGAEVVVKRVPETMP
                     PQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGA
                     LYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPY
                     GATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG"
     gene            25217..25444
                     /locus_tag="RHX21_002606"
     CDS             25217..25444
                     /locus_tag="RHX21_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002898701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccJ family protein"
                     /protein_id="HDV1987767.1"
                     /translation="MPTQEAKAHHVGEWASLRNTSPEIAEAIFEVAGYDEKMAEKIWE
                     EGSDEVLVKAFAKTDKDSLFWGEQTIERKNV"
     gene            complement(25482..26723)
                     /gene="agp"
                     /locus_tag="RHX21_002607"
     CDS             complement(25482..26723)
                     /gene="agp"
                     /locus_tag="RHX21_002607"
                     /EC_number="3.1.3.10"
                     /EC_number="3.1.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glucose-1-phosphatase/inositol
                     phosphatase"
                     /protein_id="HDV1987768.1"
                     /translation="MNKTLIAAAVAGIVLIASNAQAQTVPEGYQLQQVLMMSRHNLRA
                     PLANNGSVLEQSTPNKWPEWDVPGGQLTTKGGVLEVYMGHYMREWLAEQGMVKSGECP
                     PPDTVYAYANSLQRTVATAQFFITGAFPGCDIPVHHQEKMGTMDPTFNPVITDDSAAF
                     SEQAVAAMEKELSKLQLTDSYQLLEKIVNYKDSPACKEKQQCSLVDGKNTFSAKYQQE
                     PGVSGPLKVGNSLVDAFTLQYYEGFPMDQVAWGEIKSDQQWKVLSKLKNGYQDSLFTS
                     PEVARNVAKPLVSYIDKALVTDRTSAPKITVLVGHDSNIASLLTALDFKPYQLHDQNE
                     RTPIGGKIVFQRWHDSKANRDLMKIEYVYQSAEQLRNADALTLQAPAQRVTLELSGCP
                     IDANGFCPMDKFDSVLNEAVK"
     gene            complement(27012..>27364)
                     /locus_tag="RHX21_002608"
     CDS             complement(27012..>27364)
                     /locus_tag="RHX21_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000097604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987769.1"
                     /translation="NDKKCILHLPEFIFNDNKVRLVLDTDPEQRVNEVKNFLTALSDS
                     ICSLFIVNSNMASISLGNESFSTDEDLEYGYLMNTGNHYDVYLPPELFAQAYKLNNKE
                     MNAQLDYLNRYAIY"
BASE COUNT         6677 a         7079 c         6928 g         6680 t
ORIGIN      
        1 attggaatgg attttcgggc gagaaaagga ttttatatgg acactctgct catcatttct
       61 tcttctcatc atcaacaatt cacgtctctc ttccgcgttt aataacggat tatgaggtgc
      121 aaaaatatct ttcttttcag ttacctgtaa ttagatacag agagagattt tggcaataca
      181 tggagtaata caggatgtat tcaagtagca gaaaaaggtg cccgaaaacc aaatgggctt
      241 tgaaacttct tactgccgca tttttagcag cgagtcccgc ggcgaagagt gctgttaata
      301 acgcctatga tgcattgatt attgaagctc gcaagggtaa tactcagcca gctttgtcat
      361 ggtttgcact aaaatcagca ctcagcaata accaaattgc tgactggtta cagattgcct
      421 tatgggccgg gcaagataaa caggttatta ccgtttacaa ccgctaccgt catcagcaat
      481 taccagcgcg tggttatgca gctgtcgccg tcgcttatcg taacctgcaa caatggcaaa
      541 actcgcttac actgtggcaa aaggcgctct ctctggagcc gcaaaataag gattatcaac
      601 ggggacaaat tttaacccta gcagatgctg gtcactatga tactgcgctg gttaaactta
      661 agcagcttaa ctctggagca ccggacaaag ccaatttact cgcagaagcc tatatctata
      721 aactggcggg gcgtcatcag gatgaattac gggcgatgac agagtcatta cctgaaaatg
      781 catctacgca acaatatccc acagaatacg tgcaggcatt acgtaataat caacttgctg
      841 ccgcgattga cgatgccaat ttaacgccag atattcgcgc tgatattcat gccgaactgg
      901 tcagactgtc gtttatgcct acgcgcagtg aaagtgaacg ttatgccatt gccgatcgcg
      961 ccctcgccca atacgctgca ttagaaattc tgtggcacga taacccagac cgtactgccc
     1021 agtaccagcg tattcaggtt gatcatcttg gcgcgttatt aactcgcgat cgttataaag
     1081 acgttatttc tcactatcag cgattaaaaa agacggggca aattattccg ccctgggggc
     1141 aatattgggt tgcatcggct tatctcaaag atcatcagcc gaaaaaagca cagtcaataa
     1201 tgaccgagct cttttatcac aaggagacca ttgccccgga tttatccgat gaagaacttg
     1261 cggatctctt ttacagccac ctggagagtg aaaattatcc gggcgcgcta actgtcaccc
     1321 aacataccat taatacttcg ccgcctttcc ttcggttaat gggcacgcct acgagcatcc
     1381 cgaatgatac ctggttacag gggcattcgt ttctctcaac cgtagcaaaa tatagtaatg
     1441 atcttcctca ggctgaaatg acagccagag agcttgctta taacgcacca ggaaatcagg
     1501 gactgcgcat tgattacgcg agtgtgttac aagcccgcgg ttggcctcgt gcagcagaaa
     1561 atgaattaaa aaaagcagaa gtgatcgagc cacgtaatat taatctggag gttgaacaag
     1621 cctggacagc attaacgtta caagaatggc agcaggcagc tgtcttaacg cacgatgttg
     1681 tcgaacgtga accgcaagat cccggcgttg tacgattaaa acgtgcggtt gatgtacata
     1741 atcttgcaga gcttcgtatc gctggctcaa caggaattga tgccgaaggc ccggatagtg
     1801 gtaaacatga tgtcgactta accaccatcg tttattcacc accgctgaag gataactggc
     1861 gcggttttgc tggattcggt tatgccgatg gacaatttag cgaaggaaaa gggattgttc
     1921 gcgactggct tgcgggtgtt gagtggcggt cacgtaatat ctggctcgag gcagagtacg
     1981 ctgaacgcgt tttcaatcat gagcataaac ccggcgcgcg cctgtctggc tggtatgatt
     2041 ttaatgataa ctggcgtatt ggttcgcaac tggaacgcct ctctcaccgc gttccattac
     2101 gggcaatgaa aaatggtgtt acaggcaaca gtgctcaggc ttatgttcgc tggtatcaaa
     2161 atgagcggcg taagtacggt gtctcctggg ctttcactga tttttccgac agtaaccagc
     2221 gtcatgaagt ctcacttgag ggtcaggaac gcatctggtc ttcaccatat ttgattgtcg
     2281 atttcctacc cagtctgtat tacgaacaaa atacagaaca cgatacccca tactacaacc
     2341 ctataaaaac gttcgatatt gttccggcat ttgaggcaag ccatttgtta tggcgaagct
     2401 atgaaaatag ctgggagcaa atattcagcg caggtgttgg tgcctcctgg caaaaacatt
     2461 atggcacgga tgtcgtcacc caactcggct acgggcaacg cattagctgg aatgacgtga
     2521 ttgatgctgg cgcaacgcta cgctgggaaa aacgacctta tgacggtgac agagaacaca
     2581 acttatacgt tgaattcgat atgacattca gattttaagg ataaatatgt tacgtaatgg
     2641 aaataaatat ctcctgatgc tggtgagtat aattatgctc accgcgtgca ttagccagtc
     2701 aagaacatca tttataccgc cacaggatcg cgaatcttta ctcgccgagc aaccgtggcc
     2761 gcataatggt tttgtagcga tttcatggca taacgttgaa gacgaagctg ccgaccagcg
     2821 ttttatgtca gtgcggacat cagcactgcg tgaacaattt gcctggctgc gcgagaacgg
     2881 ttatcaaccg gtcagtattg ctcaaattcg tgaagcacat cgaggaggaa aaccgctacc
     2941 ggaaaaagct gtagtgctga cttttgatga cggctaccag agtttttata cccgcgtctt
     3001 cccaattctt caggccttcc agtggcctgc tgtatgggcc cccgtcggca gttgggtcga
     3061 tacgccagcg gataaacaag taaaatttgg cgatgagttg gtcgatcgag aatattttgc
     3121 cacgtggcaa caagtgcgag aagttgcgcg ttcccggctc gttgagctcg cttctcatac
     3181 atggaattct cactacggta ttcaggctaa tgccaccggc agcttattgc ctgtatatgt
     3241 aaatcgtgca tattttactg accacgcacg gtatgaaacc gcagcagaat accgggaaag
     3301 aattcgtctg gatgctgtaa aaatgacgga atacctgcgt acaaaggttg aggtaaatcc
     3361 acacgttttt gtttggcctt atggcgaagc gaatggcata gcgatagagg aattaaaaaa
     3421 actcggttat gacatgttct tcacccttga atcaggtttg gcaaatgcgt cgcaattgga
     3481 ttccattccg cgggtattaa tcgccaataa tccctcatta aaagagtttg cccagcaaat
     3541 tattaccgta caggaaaaat caccacaacg gataatgcat atcgatcttg attacgttta
     3601 tgacgaaaac ctccagcaaa tggatcgcaa tattgatgtg ctaattcagc gggtgaaaga
     3661 tatgcaaata tcaaccgtgt atttgcaggc atttgctgat cccgatggtg atgggctggt
     3721 caaagaggtc tggtttccaa atcgtttgct accaatgaaa gcagatattt ttagtcgggt
     3781 tgcctggcaa ttacgtaccc gctcaggtgt aaacatctat gcgtggatgc cggtattaag
     3841 ctgggattta gatcccacat taacgcgagt aaaatactta ccaacagggg agaaaaaaac
     3901 acaaattcat cctgaacaat atcaccgtct ctctcctttc gatgacagag tcagagcaca
     3961 agttggcatg ttatatgaag atcttgccgg acatgctgct tttgatggca tattgttcca
     4021 cgatgatgct ttgctttcag attatgaaga tgccagtgca ccggctatca cggcttatca
     4081 gcaagcaggc tttagcggga gtctgagcga aattcgacaa aacccggagc aatttaaaca
     4141 gtgggcccgc tttaaaagtc gtgcgttaac tgacttcact ttagaactta gtgcgcgcgt
     4201 aaaagccatt cgcggtccac atattaaaac tgcacgaaat atttttgcac ttccggtaat
     4261 acaacctgaa agtgaagcct ggtttgcaca gaattatgct gatttcctaa aaagctatga
     4321 ctggaccgct attatggcta tgccttatct ggaaggtgtc gcagaaaaat cggctgacca
     4381 atggttaata caattgacca atcaaattaa aaacatccct caggctaaag acaaatctat
     4441 tttagaatta caggcacaaa actggcagaa aaatggtcag catcaggcta tttcttcgca
     4501 acaactcgct cactggatga gcctattaca actgaatgga gtgaaaaact atggttatta
     4561 tcccgacaat tttctgcata accaacctga aatagacctt attcgtcctg agttttcaac
     4621 agcctggtat ccgaaaaatg attaatcgca tcgtatcgtt ttttatatta tgtctggtgt
     4681 tatgcatacc cctatgcgta gcgtactttc actctggtga actgatgatg aggttcgttt
     4741 tcttctggcc gttttttatg tccattatgt ggattgttgg cggcgtctat ttctgggtct
     4801 atcgtgaacg ccactggccg tggggagaaa acgcaccagc tccccagttg aaagataatc
     4861 cgtctatctc cattatcatt ccctgtttta atgaggagaa aaacgttgag gaaaccatac
     4921 acgccgcttt agcacagcgt tatgagaaca ttgaagttat tgccgtaaat gacggttcaa
     4981 cagataaaac ccgtgccatc ctggatcgca tggctgcaca aattccccat ttgcgggtca
     5041 ttcatctggc gcaaaaccag gggaaagcca ttgcgcttaa aaccggagct gccgcggcga
     5101 aaagtgaata tctggtgtgc attgatggcg atgcgttatt agaccgcgat gcggcggcat
     5161 atattgtgga accgatgttg tacaacccgc gtgtgggtgc cgtaaccggt aatcctcgta
     5221 ttcgaacacg ttctaccctg gtgggtaaaa ttcaggttgg cgagtattcc tcaattattg
     5281 gtttgatcaa gcgaacccag cgtatctatg gaaacgtatt taccgtttcc ggtgttattg
     5341 ccgcatttcg tcgcagcgcc ctggcagaag tgggttactg gagtgacgat atgatcaccg
     5401 aagatattga tattagctgg aagctgcagt tgaatcagtg gacgattttt tacgagccac
     5461 gggcgctgtg ctggatatta atgcctgaaa cgttaaaagg gctgtggaaa cagcgcctgc
     5521 gctgggctca gggcggtgca gaagtattcc tcaaaaatat gacaaggttg tggcgcaaag
     5581 aaaactttcg aatgtggccg ctgttttttg aatactgcct gacgacaata tgggccttca
     5641 cctgcctggt cggtttcatt atttacgcag tccaacttgc cggtgtaccg ttaaatattg
     5701 aattgacaca tatcgctgcg acacatactg ccggaatatt attgtgtacg ttatgtttac
     5761 tgcaatttat tgtcagcctg atgatcgaga atcgctatga gcataatctg acttcatcgc
     5821 ttttctggat tatttggttc ccggttattt tctggatgct gagcctggca acgacattgg
     5881 tatcatttac acgagtcatg ttgatgccta aaaagcaacg cgcccgttgg gtaagtcccg
     5941 atcgcgggat tctgagaggt taatatgaac aatttaatta ttacgacccg acaatcacca
     6001 gtacgtttac tggttgatta tgttgccaca accatcttgt ggacattatt tgcgttgttc
     6061 atattcttat tcgccatgga tctgctgacg ggttattact ggcaaagcga ggccagaagc
     6121 cgacttcagt tctatttttt gctggcagtg gcgaatgccg tcgtgttaat tgtctgggcg
     6181 ctgtacaata agctgcgttt tcaaaaacag cagcatcatg cagcctacca atatacgccg
     6241 caagaatatg cagagagctt agcaatacct gatgagctct atcagcaact acaaaaaagc
     6301 cacaggatga gcgtacactt caccagccag gggcaaataa aaatggttgt ttcagaaaaa
     6361 gcgctagtcc gggcataaac acccaaaaca aagcccggtt cgcccgggct ctgcaccgat
     6421 aatacactta actgtatgca tgcagcgtac gttggcaaag tgccgaacgt acgcagtcct
     6481 ctttaccgaa ccggacgatc ccaaccattt catcttcttc gaaacgttcc agcgcgtcac
     6541 ttaatccgga gcacacgccg cgaggcaaat cgcattgcgt gatatcaccg ttgacgataa
     6601 ccgtcacgtt ctccccgagg cgggttaaaa acattttcat ttgcgcggca gtcacattct
     6661 gcgcctcgtc aagaatgacg actgcatttt caaaggtacg tccacgcata taggcgaacg
     6721 gcgcaatttc caccttccct atttccggtc gcaggcagta ctgcataaag gaagccccta
     6781 agcgccggac cagcacgtcg tagaccgggc gaaaataggg agcaaacttt tctgcgatat
     6841 ctccaggtaa gaagccaaga tcttcatcgg cttgcagaac tggacgggtg acgataatcc
     6901 tgtcgacatc cttatgtatc agggcctctg ccgcttttgc tgcgctgatc caggtttttc
     6961 cgcacccggc ttcgcccgtg gcgaatatca gctgcttact ctcaatagcc ttcagatagt
     7021 gcaattgcgc ttcatttcgc gcgaggatgg gcgaagtatc gcgactgtcg cgggccatac
     7081 caatggcttc tacgccgccc atctgcacaa gcgaggtgac cgattcttct tcacgctgct
     7141 tatggctgcg cgaatcccgt ctcagcacac gttttgcctc acgacgagct ttgatcactg
     7201 ctttttgtct tcccatggag agcaccttga gttgtttgta ttcatcacac gcgccgttgg
     7261 cagcgcgatt atgcgcacga acatcagagg gttggcttcc ttgtaagcca tagtttgctt
     7321 ttggataaaa tgccgaaaaa cggctacgca caccgtttgc ggcgtcggta acacgagtaa
     7381 agagaggaag tgagaaaaat acagagtgac gaagttgcta ccggaggaga aatctccgca
     7441 agtggtggag cgtagcttaa caagacattg tccagaacag gacgttacca tccgcgatct
     7501 ccatagtgac tgactatcac tgccgggaac ttccgctgct acttaataat tacaacagat
     7561 ctcgcattca ttgcaacaat atattcactt atatttaacc ataaaacacc atttcagtga
     7621 cattagtttc tactggaaag atgacagagt gatgacagat atgaaaaaag ctgtgtgctt
     7681 tcagcaggat tcgcatcagg catctgcgca cgaacgccgg atgcggcgtg aacgccttat
     7741 ccgcctaccg aacccgcacc gattgtaggc ataagaagac gcgcaagcat cgcatcaggc
     7801 atctgcgcaa gaacgcctta tccgtctata aacattaaac ccgcaataac gcgcttccga
     7861 gataatcgtt cgcgtccttc actcccggca gcgcaaaaaa ataaccgccg ccgataggtt
     7921 taacgtattc ctccagcgct tcgccattga gccttttttg tacagtcagg aagccttttt
     7981 ccagatcgtg ttggtaacag acaaacagta gccccatatc cagttgcccg gagttggtga
     8041 cgcccagtga ataactgtag ccacgacgca gcatcaggct ggactcactc tccgccgtgc
     8101 ggggattcgc cagccggata tggctgtcca gcgcaatcac cttcccttcc ggatcgctgg
     8161 cgtaatcggg aacatcatgc tcatgctgca ttcccagcgg cgcaccggtt tgcttatcac
     8221 gaccaaaaat cgtctgctgt tctttcagcg gagttctgtc ccaaaattcc actcgaaact
     8281 gaatcaagcg tactgcctga tagctgccac cgattgtcca cgctggctcc tgctgatctg
     8341 ccgttaccca caccactttt tgcatcaact tatcattctg gctatcggga ttggcagtgc
     8401 cgtctttgaa acccagcaaa ttaatcggcg tctctttgcc tttactacgc gccgcgtgat
     8461 cggaaataaa cccttcccgc ttccagcgca cgctgagcaa atctggcgta tgtttgatga
     8521 tatcgcgcag cgcatggatc accgtgtcct gggtgttggc gcaaatttgt agcaacacat
     8581 caccatgaca taacgccgca tccagcgagt cgttgggaaa acgcgtcatc ttctgcaact
     8641 ttttcggcat ctgtggcgca aggccaaagc gctcatcaaa caatgagtga cccaccgata
     8701 acgtgatggt gagattatcg ggcgcaatgt agccgccaag aatgccggaa tcgagtggtg
     8761 gcaggcgcgg atttggcgtt tctggtgccg ctccgccctg agtcagaaaa gcaaaacgct
     8821 gagtcaacaa gcgaaacaac cgttcaagat cgggtttatc gctggcaagc acatcaaacg
     8881 ccaccagcat cattgcggcc tgttgtggcg tcaggatccc tgcctgatgc tcaccataaa
     8941 acggctgttt ctcattgcgt gcatccggtg aaagcgtacc cggcgcactt tgcgtttttt
     9001 gtgcatgagc gaccggacaa cttcccgcca gcgccagcgc accaatgcct ttcagtaaac
     9061 gtcggcgtga cggttcattc acgccgtttt tatcttcata ctgcataatg cttaatccaa
     9121 tcccagcaca ccgcgaagtt gcgccagatc ttccgccagc gcagtaatcg gtcctttcag
     9181 tgcattccgg tcggcatcgg tcaatttgtc gtaggtttca aaaccgtctt tagtacggta
     9241 tttcgccaga atggtatcga cctttttaaa gttggcatcg acttttgcca acagttccgg
     9301 gttggctttt tgcagttgtg gacgcagcag atcgacaatt ttctgcgagc cttcaacgtt
     9361 agcctggaaa tcccacagat cggtgtggct gtagcgatct tcttcaccgc tgattttgct
     9421 ggctgccact tcctcaatca gtccggctgc accgccgacc acttttgaag gtgggaaagc
     9481 cagttcactg atgcgttttt gcaaatcgac cacatcggta taaagctggt cagcgtactg
     9541 atccatgcct ttggtggtgt tgtcgccaaa caatgctttt tccagacggt ggaaaccggt
     9601 gaatttcgga tcggcggctt tttgctcgta atcatcttca cgggcgtcaa tgctgccatc
     9661 cagatcggag aacagttcag caatcggttc gatgcgctca tagtgctggc gcgtcggcgc
     9721 atacagtgct ttcgcttttt cgatatcgcc tgctttaata gcgtcagtaa aggctttcgt
     9781 gtcggtcacc agctgcgtgg tttccgccat gacatacgct ttatatgcag taattgcacc
     9841 accaagactt aacagcgcat cactttgcgc cgcatccgcc gttgcctcac ctttgacgat
     9901 caacttccct ttcgggttag tcagcagacc gcaggtcata tcgtattcgc caggctgtaa
     9961 attcgccgtc attttctggc taaagccagg ggcgatattt tcccgctctt ccaccaccat
    10021 cacgcctttg aggatctccc actccagcgc cttctggctg tggttctgaa taatgaactg
    10081 tgttttcccg gcgttaaccg taatggtcat cggttcgcac tgcttatcgg tcacggtcac
    10141 cttgacctgc ggcacattag cggcgttagc cataaaagca gaagagaaca gcgcagccac
    10201 gctcaactgc aatgcgttac ggcggaagtt aatggtcatg acgagactat ccctttaaag
    10261 tatgttgtaa ctaagcaaga gtttgcgtcg tatttgttac gcggagcgag acgctgtcgc
    10321 ccctgcgcgt ggtggcagag caaatgccac cagcgccggg atgagataaa taaaccagac
    10381 ggcgacttcg ctgacgctcg gcgcttcctg atagccaaaa atcccttcca tcagcgtgcc
    10441 aaacagcgag tgagttgaga gcaccgcact catatcgaag gcgatttcct gaaagtggtt
    10501 ccacaatccg gcttcatgaa atgcgcgaat ggcaccagcc gccagccctg cggcgacgaa
    10561 gagaataaac aggctggtcc atttaaaaaa tgcaccaaga ttgaggcgaa taccgcccca
    10621 gtagagcagg aagcctagca ccacggcagt agcaagaccg agcattgcac ccagcggcgg
    10681 ccagatcccg acatcttgtt gaaatgccgc cagcaggaaa aagaccgact ccagcccttc
    10741 ccttgcaacg gcaaaaaaga ccatcatcac cagcgcccag ccatgatgat ttccacgctg
    10801 caatgcgcta tcgactgcct gctccagttg tactttgacg ttgcgcgaca ctttgcgcat
    10861 ccagaaaacc atccaggtaa ggatcaccac ggcgatcacc gccacgatac cttcaaacag
    10921 ttcctgctct ttttgcggaa attcgccggt ggtttcgtta atgaagatcc ccaagcccag
    10981 gcacaacgca gcggcaagca acacgccaat ccacatcaca ccaatccatc ggcctcgctg
    11041 ggtacgctta agatagctgg caatcaaact gacaatcagc gcggcttcaa gtccttcgcg
    11101 caacataatg agaaacggaa caaacatgcc acccaccctt aaacgttttt ctgagtcaat
    11161 ctatgcaaag aaaagtaaat cgcagtgata gcgattatca ttacggtaaa gaaaaataca
    11221 agcggaatgt ttataaaatg atgttgaaat ataaacaaag agaggtaatg ccaggggata
    11281 taaacgatta ttccaggtac aaagatggga ttgtttacaa cgagccatgt gttcttgccg
    11341 gatgccgcgt aaacgccgta tccagccgac aaaaccgtcc tgactcaata catcaaaact
    11401 tccatgtaaa actgataagc gggtgtatca agcaatttcg tccatcctcg attatcaaat
    11461 ctaacttttt gcccggaaca taataacagc tcgggtgttg gtggcgtcaa aatcgctgaa
    11521 gcgttccccg aaggccggga cagcaggggg ccgcggcgat tggccgcccc ctgcgcgctc
    11581 cctgcaccat tcaatttata tggcgaggca cattaaggga gcgcaacccg ctgctgaagc
    11641 caaacaaaac cgccgcaggc taagtccctt agctttcctg caaccgtgac ggcggagccg
    11701 aatgatagtg cgcatcggcc tcggcaaagc gtttttgcat cgccgctgac ggcgctttac
    11761 ccagcaaact aaacactaca atcccgatac tgccgaagat gaagcccgga ataatttcgt
    11821 agagtcccag ccagccgaac tgcttccaga cgataaccgt cagcgcaccg atgatcatcc
    11881 ccgccagcgc accgttgcgc gtcatgcgtg accacatcac cgagaacagc accaccggac
    11941 caaacgccgc gccaaagcct gcccacgcgt agctcactaa gcccagcacg cggttttccg
    12001 ggtttgccgc cagcgcaatc gccaccagcg ccaccaccag caccatcaca cgccctaccc
    12061 acaccagctc tttctggctg gcatgtttac gcagaaacgc tttgtataaa tcttcggtaa
    12121 tcgcactgga gcacaccagc agctggcaac ttaaggttga cattaccgcc gccagaattg
    12181 ccgacagcag aatcccggca atccacgggt taaacagaat ttgcgccagt tcgataaaca
    12241 cgcgctcagc attctggttt accgcacctg ctaccgccgg gtgctcatta aagtaagcaa
    12301 taccaaagaa gccgacagct accgcccctg ccaggcagag gatcatccag gtcatactga
    12361 tacgacgcgc atggacaatg ctgtggtgag agtctgccgc cataaaacgc gccaggatgt
    12421 gcggctgccc gaagtaaccc agcccccaac ccatcagtga gataatggcg acaaagttca
    12481 gccctttgag catatcaacg ttttcgatgc tcttttgttt gatcacttcc agcgagtcac
    12541 caaagccacc gacactgata atgacgataa ccggcgtcag gatcagggca aaaatcatca
    12601 ggctggcctg tacagtgtca gtccagctca ccgcgaggaa accgccaata aaggtgtaaa
    12661 ggatcgtcgc cgcagctccc gcccacagag ccgtttcgta gctcatgcca aaggtacttt
    12721 caaacagacg cgcgcctgcc acaatgcccg aagcgcaata aatggtgaag aacagcaaaa
    12781 tcaccagcgc ggagataatg cgcaaaatgc ggcttttatc ttcaaagcgc ccggtgaaat
    12841 aatccggcaa tgttaaggcg ttattgttgt attcggtatg cacacgcaac cgccccgcca
    12901 ccagcttcca gttgatccac gcgcctaatg tcaggccaat ggcgatccaa ctttcggaaa
    12961 tcccggaaag aaaaaccgcg cccggcaacc ccattaacag ccagccgctc atatccgacg
    13021 cacccgccga taatgccgtc acgaatggcc caaggctacg accgcccaga atatagtcgt
    13081 caaagttttt cgttgatcgc caggcgataa acccaatcaa tatcatgcca aagatataga
    13141 cacaaaatgt caccaacatc ggtgtgctaa tagccatcta aagtctccaa aaaattatta
    13201 tcggcaatgt cgaaacttgc cgttatatct gccaccggaa cggggtaaca gagtttatgt
    13261 tttaccaggg cgaccgtatc ctgccggaag cgctggttat tcacaatcga tttaacacac
    13321 catttacatt aaattttagt gctcagcgac actatttttc atcaggttgc actctctcac
    13381 attttttgcg gttgcacctt tcaaaaatgt taactgccgc agagaaaaag tctgagttat
    13441 ttttttaatc cctgtcatat cgatttcttt tattaacatt tcattcattt ttaagcttgc
    13501 tacgcatgtc acatttaaca tggttgcaca aagttgcaac atcatggata tttcacgata
    13561 acgttaagtt gcacctttca gaacaacagg agtaatggca tgggaaccac caccatgggg
    13621 gttaagctgg acgacgcgac gcgtgagcgt attaagtctg ccgcgacacg tatcgatcgc
    13681 acgccacact ggttaattaa gcaggcgatt ttttcttatc tcgaacaact ggaaaacagc
    13741 gatactctgc cggagctacc tgcgctgctt tctggcgctg ccaatgagag cgatgaagca
    13801 ccgactccgg cagaggaacc acaccagcca ttcctcgact ttgccgagca aattttgccc
    13861 cagtcggttt cccgcgccgc gatcacagcg gcctatcgcc gcccggaaac cgaagcggtt
    13921 tctatgctgc tggaacaagc ccgcctgccg cagccagttg ctgaacaggc gcacaaactg
    13981 gcgtatcaac tggccgataa actgcgtaat caaaaaaacg ccagtggtcg cgcaggtatg
    14041 gttcaggggt tattgcagga gttttcgttg tcatcgcagg aaggcgtggc gctgatgtgt
    14101 ctggcggaag cgttgttgcg tattcccgac aaagccaccc gtgatgcgtt aattcgcgac
    14161 aaaatcagca acggtaactg gcaatcacac attggtcgta gcccgtcttt gtttgttaat
    14221 gccgccacct gggggctgct gtttactggc aaactggttt ccacccataa cgaagccagc
    14281 ctctcccgct cgctgaaccg cattatcggt aaaagcggtg aaccgctgat ccgcaaaggt
    14341 gtggatatgg cgatgcgcct gatgggcgag cagttcgtca ctggcgaaac catcgcggaa
    14401 gcgttagcca atgcccgcaa gctggaagag aaaggtttcc gttactctta cgatatgctt
    14461 ggcgaagctg cactgactgc cgcagatgca caagcgtata tggtttccta tcagcaggcg
    14521 attcacgcca ttggtaaagc gtccaatggt cgtggcatct atgaaggtcc gggcatttca
    14581 atcaagctgt cggcgctgca tccgcgttac agccgcgccc agtatgaccg ggtaatggaa
    14641 gagctttacc cacgtctgaa atcactcacc ctgctggcgc gtcagtacga tattggtatc
    14701 aacattgacg ccgaagaggc cgatcgtctg gagatctccc tcgatctgct ggaaaaactc
    14761 tgtttcgagc ctgagctggc aggctggaac ggtatcggtt ttgttattca ggcttatcaa
    14821 aaacgctgcc cactggtgat tgattacctg attgatctcg ccacccgcag ccgtcgccgt
    14881 ctgatgattc gcctggtgaa aggcgcgtac tgggatagtg aaatcaagcg tgcgcagatg
    14941 gacggccttg aaggctatcc ggtttatacc cgcaaggtgt ataccgacgt ttcatatctc
    15001 gcctgtgcga aaaagctgct ggcggtgccg aatctaatct acccgcagtt cgcgacgcac
    15061 aacgcccata cgctggcagc gatttatcaa ctggcaggtc agaactacta tccgggtcag
    15121 tacgagttcc agtgcctgca tggtatgggc gagccactgt atgagcaggt caccgggaaa
    15181 gttgccgacg gcaaacttaa ccgtccgtgt cgtatttatg ctccggtcgg tacccatgaa
    15241 acgctgttgg cgtatctggt gcgtcgcctg ctggaaaacg gtgctaacac ctcgtttgtt
    15301 aaccgtattg ccgacacctc tttgccactg gatgaactgg tcgccgatcc ggtcactgct
    15361 gtagaaaaac tggcgcaaca ggaagggcaa actggattac cgcatccgaa aattcccctg
    15421 ccgcgcgatc tttacggtca cgggcgcgac aactcggcag ggctggatct cgctaacgaa
    15481 caccggctgg cctcgctctc ttctgccctg ctcaatagtg cactgcaaaa atggcaggcc
    15541 ttgccaatgc tggaacaacc ggtagcggca ggtgagatgt cgcccgttat taaccctgcg
    15601 gaaccgaaag atattgtggg ctttgtgcgt gaagccacgc cgcgtgaggt agaacaggcg
    15661 ctggaaagtg cggttaataa cgcgccaatc tggtttgcca ctcctccggt tgaacgcgcg
    15721 gcgattttgc atcgcgctgc cgtgctaatg gaaagccaga tgcagcaact gattggtatt
    15781 ctggtgcgtg aagccggaaa aaccttcagt aacgccattg ccgaagtgcg cgaagcggtc
    15841 gattttctcc actactatgc cggacaggtg cgggatgatt tcgctaacga aacccaccgt
    15901 ccattagggc ctgtggtgtg tatcagtccg tggaacttcc cgctggctat tttcaccggg
    15961 cagattgctg ccgcactggc ggcaggtaac agcgtgctgg caaaaccggc agaacaaacg
    16021 ccgctgattg ccgcgcaagg gatcgccatt ttgctggaag cgggtgtacc gccaggcgtg
    16081 gtgcagttgc tgccaggtca gggggaaacc gtgggcgcgc aactgacggg tgatgatcgc
    16141 gtacgcgggg tgatgtttac cggttcaacc gaagtcgcta cgttactgca gcgcaatatc
    16201 gccagccgcc tggacgctca gggtcgccct attccgctca tcgctgaaac cggcggcatg
    16261 aacgcgatga ttgtcgattc ttcagcactg accgaacagg tcgtcgtgga tgtactggcc
    16321 tcggcgttcg acagtgcggg tcagcgttgt tcggcgctgc gcgtgctgtg cctgcaagat
    16381 gagattgccg accacacgtt gaaaatgctg cgcggcgcaa tggccgaatg ccggatgggt
    16441 aatccgggtc gcctgaccac cgatatcggt ccggtgattg atagcgaagc gaaagccaat
    16501 attgagcgcc atattcagac catgcgtagc aaaggccgtc cggtgttcca ggcggtgcgg
    16561 gaaaacagcg aagatgcccg tgaatggcaa agcggcacct ttgtcgcccc gacgctgatc
    16621 gaactggatg actttgccga attgcaaaaa gaggtctttg gtccggtgct gcatgtggtg
    16681 cgttacaacc gtaaccagct accagagctg atcgagcaga ttaacgcttc cggctatggt
    16741 ctgacgcttg gtgtccatac gcgtattgat gaaaccatcg cccaggtcac tggctcggcc
    16801 catgttggta acctgtatgt taaccgtaat atggtgggcg cagtggtggg tgtgcagcca
    16861 ttcggcggcg aagggttgtc cggtaccggg ccgaaagcag gcggtccgct ctatctctac
    16921 cgtctgctgg cgaatcgccc ggaaagtgcg ctggcagtga cgctcgcgcg tcaggatgca
    16981 gagtatccgg tcgatgcaca gttgaaagcc gcattgactc agccgctaaa tgcactgcgg
    17041 gaatgggcag caaatcgtcc agaattgcag gcgttatgta cgcaatatgg cgagctggcg
    17101 caggcaggaa cacaacgatt gctgccgggg ccgacgggtg aacgcaacac ctggacgctg
    17161 ctgccgcgtg agcgcgtgtt gtgtattgcc gatgatgagc aggatgcgct gactcagctc
    17221 gccgccgtgc tggcggtggg cagccaggta ctgtggccgg atgacgcgct gcatcgtcag
    17281 ctagtaaagg cattgccatc ggcagtcagc gaacgtattc aactggcgaa agcggaaaat
    17341 ataaccgctc aaccctttga tgcggtgatc ttccacggtg attcggatca gcttcgcgca
    17401 ttgtgtgaag ccgttgctgc gcgggatggc gcaattgttt cggtgcaggg ttttgcccgt
    17461 ggcgaaagca atatccttct ggaacggctg tatatcgaac gttcgctgag tgtgaatacc
    17521 gctgccgctg gcggtaacgc cagtttaatg actataggtt aaacaggtag ccggaggatg
    17581 ttacaacctc ctccggcatc tttaacgtgg tcgaatcccc tcaataataa tccgctgcac
    17641 gttttcaacc gtttgattga aaaatatctc atcgcgcaac gtcgcgcctg tcaccgcctc
    17701 cacctgaggg gcgaaatcgg cgtaatgttg agtggaagcc caaatcatga aaatcaaatg
    17761 ctgcggatca atcggcgcga gtttgccgct tttgacccaa ccggcaatca gcgccgattt
    17821 ctcatcaatt aatgccttca aatcgcccgt cagttcatcc attaacagcg gcgcgcctgc
    17881 cagcatctcc atacagaaca ggcgcgaagc ctgcggataa tcgcgtgaga cttccagctt
    17941 cagacggatg tactctttga tcgccgccag cggggcgaaa tcttcacgaa acgcttttaa
    18001 cggtgccagc cagatatcga gaatctgccg cagcacggca atatacagcg cctcttttga
    18061 cgggaagtaa tacagcagat tggtttttga aacacccgcc aactctgcga tctgctccag
    18121 ccttgtgccg tgaaaaccga attgtgaaaa agtgtccagt gctgcgctaa gaatcgcttt
    18181 tttcttcgcg cttactgcgc gcgaacgttt acccgttgtt ttcactgcgc cttgcgtcat
    18241 gcgctctccc ctcttgtaga ttggcaacag gatagcaaaa cccccgcccg gcctcgacct
    18301 tctgcactct catcgcgcac agatgcatgt tttatgtgca actgttttga ccgtttagtc
    18361 cactttttac cagatatttt agacaacaca atgttaacac attaataaca ttcacttttt
    18421 aaaaactggc atccgctttg caaacaagcc attacgcggc tgaaaaggat atgcaggatg
    18481 cagcgccccg tctgactttc actttacgag acgaagagag gttgatgatg aaaattggcg
    18541 tattcgtacc tattggcaac aacggctggc tcatttcgac ccacgcgccg cagtacatgc
    18601 cgacctttga actgaataaa gccattgtgc aaaaagcgga gcactaccat ttcgatttcg
    18661 ccctgtcgat gatcaaactg cgtggctttg gcggcaaaac tgagttctgg gatcacaacc
    18721 ttgagtcgtt caccttgatg gcggggctgg cggccgtgac ctcgcgcatt cagatttacg
    18781 ccactgctgc caccttaacg ttacctccgg caatcgtcgc ccgtatggcc gcaaccatcg
    18841 actccatctc tggcgggcgt tttggcgtca acctcgtgac tggctggcaa aagcccgagt
    18901 atgagcagat gggtatctgg cctggcgatg actatttctc ccgtcgttac gactatctca
    18961 ccgaatatgt tcaggtgctg cgcgacctgt ggggcacggg gaaaagcgat tttaaaggcg
    19021 attttttcac catgaatgat tgtcgcgtca gtccgcaacc gagtgtcccc atgaaagtga
    19081 tctgcgccgg gcaaagcgac gctggcatgg cgttctccgc ccagtatgcc gatttcaact
    19141 tctgtttcgg caaaggcgta aatacgccca cggctttcgc cccgaccgct gcgcggatga
    19201 aacaggccgc agagcaaacc gggcgcgacg ttggttctta tgtgttgttt atggtgattg
    19261 ccgatgaaac cgacgatgcc gctcgcgcca aatgggaaca ctacaaagcg ggcgcggatg
    19321 aagaggcgtt aagctggcta accgaacaaa gtcagaaaga tacccgctcc ggtactgata
    19381 ccaacgtccg tcagatggcc gatcccactt cggcggtaaa catcaatatg gggacgttag
    19441 tcggttctta cgccagtgtc gcgcgcatgt tagatgaagt cgcaagcgtg cctggtgccg
    19501 aaggcgtgct gttgaccttc gatgattttc tgtcgggaat cgaaaccttc ggcgagcgca
    19561 ttcaaccact gatgcagtgc cgcgcccatc tacctgcgct gactcaggag gtggcatgat
    19621 gacaacctta accgctcgac cggaagccat taccttcgat ccgcagcaaa gtgcgctgat
    19681 cgtggtggat atgcaaaacg cttatgccac gccaggcggc tacttagatc tcgccgggtt
    19741 tgatgtctca accactcgcc cggtcattgc caacattcaa accgccgtga ccgcagcgcg
    19801 agcggcaggg atgctgatca tctggtttca aaatggctgg gatgaacagt atgtcgaagc
    19861 tggcggcccc ggctcaccga attttcataa atcgaacgcc ctgaaaacca tgcgtaagca
    19921 gccgcagctg caggggaaat tgctggcgaa aggctcctgg gattatcaac tggtggatga
    19981 actggtgccg cagcctggcg atattgtgct gccgaagccg cgctacagcg gtttcttcaa
    20041 tacaccgctg gacagcattt tgcgcagccg tggaatacgc catctggttt tcaccggtat
    20101 cgctaccaac gtctgcgtcg aatcgacgct acgcgatggc ttttttctgg agtatttcgg
    20161 cgtggtgctg gaagacgcaa cacaccaggc ggggccggaa tttgcacaga aagccgcgtt
    20221 gttcaatatc gaaacctttt ttggctgggt cagcgacgtc gaaacgttct gcgacgcgct
    20281 ttctcccaca tcctttgctc gtatcgctta aggagtttaa cgatgccaaa atccgtaatt
    20341 attcccgctg gcagcagcgc accgctggcc cccttcgttc ccggcacgct ggctgatggc
    20401 gtggtgtatg tctccggtac gctggctttt gatcaacata ataacgtgct gtttgccgat
    20461 gacccaaagg cgcaaacccg ccacgttctg gaaactatcc gcaaggtgat cgagacggcg
    20521 ggtggcacga tggcggatgt gaccttcaac agcatcttta ttaccgactg gaaaaattac
    20581 gccgcgatta acgaaatcta cgccgagttt tttccgggtg ataaaccggc gcgattctgc
    20641 attcagtgcg gactggtaaa acctgacgcg ctggtggaaa tcgccacaat tgcgcatatc
    20701 gccaagtgag gccgcgatga aactttcact ctcacctccc ccttatgctg atgcgcccgt
    20761 agtggtgttg atttcgggtc ttgggggtag cggcagttac tggttaccgc aactggcggt
    20821 gctggagcag gagtatcagg tagtctgtta cgaccagcgc ggcaccggca ataatcccga
    20881 cacgctggca gaagattaca gtatcgccca gatggcagcg gaactgcatc aggcgctggt
    20941 agccgcaggg attgagcatt acgcagtggt cggccatgcg ctcggtgcgc tggtgggaat
    21001 gcagctggcg ctggattatc ccgcgtcggt aactgtgctg atcagcgtta acggctggct
    21061 acgaataaac gcccatacgc gccgctgttt tcaggttcgc gaacgattac tgtatagcgg
    21121 cggcgcgcag gcatgggtgg aagcgcagcc gttgttcctc tatcccgccg actggatggc
    21181 ggcccgcgca cctcgccttg aggcagaaga cgcgctggca ctggcgcatt ttcagggcaa
    21241 aaataattta ctgcgtcgac ttaacgccct caaacgcgct gactttagtc accatgcgga
    21301 tcgcatccgc tgcccggtgc aaatcatctg cgccagtgat gatctgctgg tgccatcagc
    21361 atgttccagt gagcttcatg ccgccctgcc cgatagccag aaaatggtga tgcgctatgg
    21421 cggacacgcc tgcaacgtga ccgaccccga aacgtttaat gctcttttac tcaacgggct
    21481 tgccagcctg ttacatcacc gcgaagccgc cctgtaagga attgctatga acgaagccgt
    21541 tagcccaggt gcgcttagca ccctgttcac cgatgcccgc actcacaacg gctggcggga
    21601 gacacccgtc agcgatgaga cgttacggga gctttatgcc ctgatgaaat gggggccgac
    21661 atcagctaac tgttctccgg cacggatcgt gtttatccgc actgtagaag gaaaagaacg
    21721 tctgcgcccg gcgctttcca gcggcaatct acaaaaaacc ctgaccgcgc ccgtcaccgc
    21781 tatcgttgcc tgggacagtg aattttatga acggttacca ctactgtttc cccacggtga
    21841 tgcccgcagt tggtttacct ccagcccaca acttgccgaa gaaacagcgt ttcgcaacag
    21901 ctccatgcag gcggcctatc tgatcgtcgc ttgccgtgcg ctgggactgg ataccggccc
    21961 gatgtcgggt tttgaccgtc aatacgttga cgacgctttt tttgcaggca gcacgctgaa
    22021 gagcaatctg ctgattaata tcggctatgg cgatagcagc aaactttatg cgcgcctgcc
    22081 acgtctgtcc tttgaagaag cctgcgggct gttgtaagga gcaaactatg aacatagttg
    22141 atcaacaaac ctttcgcgat gcgatgtcct gtatgggcgc ggcggtcaat atcatcacca
    22201 cggacggtcc agccgggcgc gccgggttca ccgccagcgc cgtctgcagc gtgaccgata
    22261 cgccgcccac attactggtg tgcctgaatc gtggggcgtc cgtctggccg gtattcaatg
    22321 aaaatcgaac gctgtgtgta aatacactga gcgccgggca ggagccgctt tcaaatcttt
    22381 ttggcggcaa aacgcccatg gaacaccgct ttgccgccgc ccgctggcag acgggtgtga
    22441 ccggatgccc gcaactggaa gaggctctgg tttcgtttga ttgccgtatc agccaggtgg
    22501 tgagcgtcgg cacccacgac attctgtttt gcgccatcga agcgattcat cgtcacgcca
    22561 caccctacgg gctggtgtgg ttcgatcgca gttatcacgc gctgatgcgc cctgcttgtt
    22621 aacctcctaa aggagacagc tgatggcaat gttcggtttt cctcactggc agttaaaatc
    22681 gacctctaca gagagcggcg tggtcgcgcc gtatgaacga ttgccgtttg ctcagacggc
    22741 agtaatgggc gttcaacacg cggtggcgat gtttggcgcg acggtgttaa tgccgattct
    22801 gatggggctg gatcccaatc tttccatttt aatgtcgggg atcggcacgt tactgttttt
    22861 ctttattacc ggcgggcgcg tccccagtta tctcggttcc agcgcggctt ttgtcggcgt
    22921 ggtgattgcc gcgacgggct ttaacggtca gggcattaac ccgaatatca gcattgcgct
    22981 gggcgggatt atcgcctgtg ggctggttta taccgtcatt ggcctggtgg tgatgaaaat
    23041 tggtacacgc tggattgaac gactaatgcc gccggtggtg acgggtgcgg tggtgatggc
    23101 gattggcctg aacttagcgc ctatcgcagt gaaaagtgta tcggcttcgg cctttgatag
    23161 ctggatggcg gtaatgacgg tgctgtgtat tgggctggtg gcggtgttta cccgtggcat
    23221 gatccagcgg ttattgattc tcgtaggatt aattgtcgcc tgtctgctgt atggcgtgat
    23281 gaccaacgtt ttagggctgg gaaaagccgt cgattttact ctcgtcagcc atgctgcctg
    23341 gttcggtttg ccacattttt ccactcctgc ttttaatggt caggcaatga tgctgattgc
    23401 gcccgtggcg gtgattctgg tggcggaaaa cttaggtcat ctcaaggcag tcgccgggat
    23461 gaccggacgc aatatggacc cgtatatggg gcgggcattc gtaggcgatg gtctggcaac
    23521 gatgctttcc ggctctgtcg gcggtagcgg cgtgaccacc tatgctgaaa atatcggtgt
    23581 gatggccgtg accaaagtct actcgacgct ggtgtttgtt gctgctgccg tcatcgccat
    23641 gctgttgggc ttttcgccga aatttggcgc gctgatccat accattcctg caccggtgat
    23701 tggtggtgct tcaattgttg tgttcgggct gattgccgtc gcaggcgcaa ggatctgggt
    23761 acaaaaccgt gtcgatttaa gccagaacgg taatttgatt atggtcgcag taaccttagt
    23821 gctgggcgcg ggtgattttg ctctcacgct gggcggtttt acgttgggag ggatcggtac
    23881 agcaaccttt ggcgcgattt tactcaatgc gttgttaagc agaaggttgg ttgacgttcc
    23941 accgccagaa gttgttcatc aggagccata aacagaaaac cgccggggta accggcggtg
    24001 atgacttttt gacgagcttc agacaaaaat gcattcgtca ctgattagtc cggctagttg
    24061 tcacttttac cgtgactgct cttgccacct tttttacctg cttcagatgc gcgctgcggg
    24121 tcattcttga aattcccccc gctgtgctgt ccaccttttt tacctgcttc tgatgctctt
    24181 tcgcggtctt ctgcaaaatt gccggaaccg cctcgatggt ttgccattac tgacctccgt
    24241 ctgggtatag acatcatatt gcatagaatt aacgcggcgt atggcggctg ccatattttc
    24301 gctacgtggg actaagctta gtgaactgac gcgggcagac ccgcgtttgg taatatcctg
    24361 caacagctta ttagcgagaa tagatatcat ctccaataat tatccataag ccgctcttat
    24421 gattaaaaaa acgcgatgag ataaaaatgt gtcattttgc gacaaaatta cgtgcttgtg
    24481 aaagttgtta taaatcaaat aagtggttgt gaaatttgca ctctgaaaag gacgtcttat
    24541 ctttaaataa gtggtagcga atcgctacgg aatagagata acacgaggag tggttagaaa
    24601 tggctaaagt tctggtgctt tattattcca tgtacggaca tattgaaacg atggcacgcg
    24661 cagtcgctga gggtgcaagc aaagtcgatg gcgcagaagt tgtcgttaag cgcgtaccgg
    24721 aaaccatgcc gccgcaatta tttgaaaaag caggcggtaa aacgcaaact gcaccggttg
    24781 caaccccgca agaactggcc gattacgacg ccattatttt tggtacacct acccgctttg
    24841 gcaacatgtc cggtcaaatg cgtaccttcc tcgaccagac gggcggcctg tgggcttccg
    24901 gcgcactata cggaaaactg gcgagcgtct ttagttccac cggtactggc ggcggtcagg
    24961 aacaaactat tacttcaacc tggacgaccc ttgcgcatca cggcatggta attgtcccca
    25021 ttggctacgc agcgcaggaa ttatttgacg tttcacaggt tcgcggcggt acgccgtacg
    25081 gcgcaaccac catcgcaggc ggtgacggct cacgccagcc aagccaggaa gaactgtcta
    25141 ttgctcgtta tcaaggggaa tatgtcgcag gtctggcagt taaacttaac ggctaatctt
    25201 caacaggagg atacgcatgc caactcaaga agcgaaagct catcacgtcg gtgaatgggc
    25261 atctctgcgc aatacgtcgc cggaaatagc cgaggccatt ttcgaagtcg ccgggtacga
    25321 cgaaaaaatg gcggaaaaga tttgggaaga aggtagcgat gaagtgttag tcaaagcctt
    25381 tgctaagacc gataaagatt cgcttttttg gggcgaacag accatcgaac gtaaaaacgt
    25441 ttaaccagcg actcccccac ttctcgcggg ggagttttct gttatttcac cgcctcattc
    25501 aacacgctat caaacttatc cattgggcag aaaccgttgg catctatcgg gcaaccgctt
    25561 aattccagcg tcacgcgctg cgcaggtgcc tgcagggtta acgcatcggc attacgtaac
    25621 tgttccgcac tctggtacac atattcaatt ttcatcaaat cgcgattggc tttgctgtca
    25681 tgccaacgct ggaaaacgat tttgccgcca atcggcgtgc gttcgttctg gtcatgcaac
    25741 tgatacggtt tgaaatccag cgccgttaac agagaggcaa tgttggagtc gtgcccaacc
    25801 aacactgtaa ttttcggtgc gctggtgcga tcggtgacca gagctttgtc gatataactg
    25861 accagcggtt tcgcaacatt gcgcgccact tccggtgagg taaacaggct gtcctggtag
    25921 ccgtttttaa gcttcgacaa caccttccac tgctggtcag atttgatttc tccccaggcc
    25981 acctgatcca tcggaaaacc ttcgtaatat tgcaaagtaa acgcatctac cagcgagttg
    26041 ccgactttca gcggcccgga aacaccaggt tcttgttgat acttggcgct aaaggtattt
    26101 ttgccatcca ccagcgaaca ctgttgtttc tctttacagg caggggaatc tttatagtta
    26161 acgatttttt ccagtagttg gtagctgtcg gtaagctgga gtttgctgag ctctttctcc
    26221 attgccgcca ccgcctgttc actgaatgcg gcggaatcat cggtgatcac cgggttaaag
    26281 gttgggtcca tagttcccat tttttcctgg tgatgcacag gaatatcaca ccccggaaat
    26341 gcgccggtaa taaagaactg tgcggtcgcg acagtacgtt gcagactatt ggcataggca
    26401 taaacggtgt ccggcggcgg gcattccccc gattttacca tcccctgctc tgccagccat
    26461 tcacgcatgt aatggcccat atacacttcg agcacgccac ctttggtggt gagttgccca
    26521 ccggggacgt cccattctgg ccatttattc ggcgtcgact gctccagcac actgccattg
    26581 ttcgccagcg gcgcacgtaa gttatggcgg ctcatcatga gcacttgctg tagctgatag
    26641 ccttccggta cggtttgtgc ctgagcgttt gaagcgatta aaactatccc tgccacagct
    26701 gcggcgatta gcgttttgtt cattcctggc acctcttttg ttatcaatca ctaaagagtg
    26761 tgacagaaat atgacatttt tccgggaaca ggctcgcaaa acagcttgtt gagcggctgt
    26821 ttttatattc atctttaaaa acaggtaagg tttgatgcaa gctatgtctg cttatcccct
    26881 gcctcgcgta caccgctgat gattacacct gtggctaaac aggatatcag cggcgttact
    26941 aatacagagg caatagtacc aataataaga gaagtgaggc taataacaat ggtttttagc
    27001 acatgccctt gtcagtaaat tgcataacga tttaaatagt cgagttgcgc attcatttcc
    27061 ttattgttta acttgtaagc ctgagcaaaa agttcaggag ggaggtaaac gtcataatga
    27121 ttgccagtgt tcattaaata accatactca agatcttcat ctgttgaaaa ggattcattc
    27181 cccaaggaga ttgatgccat attactatta acaataaata atgagcaaat gctatctgaa
    27241 agagcagtga ggaaattttt cacctcatta accctctgct ctgggtcggt gtctaaaaca
    27301 aggcgtacct tgttatcatt aaatataaat tcgggtaaat gcagtatgca ttttttgtca
    27361 ttca
//
LOCUS       DAPGUL010000057        26273 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.057, whole genome shotgun sequence.
ACCESSION   DAPGUL010000057 DAPGUL010000000
VERSION     DAPGUL010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26273)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26273)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26273
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.057"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..231
                     /gene="tuf"
                     /locus_tag="RHX21_002609"
     CDS             <1..231
                     /gene="tuf"
                     /locus_tag="RHX21_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDV1987770.1"
                     /translation="RHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVT
                     LIHPIAMDDGLRFAIREGGRTVGAGVVAKVLG"
     gene            414..608
                     /gene="bfd"
                     /locus_tag="RHX21_002610"
     CDS             414..608
                     /gene="bfd"
                     /locus_tag="RHX21_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin-associated ferredoxin"
                     /protein_id="HDV1987771.1"
                     /translation="MYVCLCNGVSDKKIRQAVRQFHPQSFQQLRKFIPVGNQCGKCIR
                     AAREVMQDELMQMPEFKEIA"
     gene            681..1157
                     /gene="bfr"
                     /locus_tag="RHX21_002611"
     CDS             681..1157
                     /gene="bfr"
                     /locus_tag="RHX21_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin"
                     /protein_id="HDV1987772.1"
                     /translation="MKGDVKIINYLNKLLGNELVAINQYFLHARMFKNWGLMRLNDVE
                     YHESIDEMKHADKYIERILFLEGIPNLQDLGKLGIGEDVEEMLQSDLRLELEGAKDLR
                     EAIAYADSVHDYVSRDMMIEILADEEGHIDWLETELDLIGKIGLQNYLQSQIKVKD"
     gene            complement(1154..1621)
                     /locus_tag="RHX21_002612"
     CDS             complement(1154..1621)
                     /locus_tag="RHX21_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDV1987773.1"
                     /translation="MDATLPFLILYACLSVLLFLWDAKHGLLPDRFTCPLLWSGLLFS
                     QVCNPDGLADALWGAIIGYGTFAVIYWGYRILRHKEGLGYGDVKFLAALGAWHTWTFL
                     PRLVFLAASFACGAVVVGLLMRGKESLKNPLPFGPFLAAAGFVVGWDSLLAGR"
     gene            2000..2311
                     /gene="rpsJ"
                     /locus_tag="RHX21_002613"
     CDS             2000..2311
                     /gene="rpsJ"
                     /locus_tag="RHX21_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014268624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HDV1987774.1"
                     /translation="MQNQRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPT
                     RKERFTVLISPHVNKDARDQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQISL
                     G"
     gene            2344..2973
                     /gene="rplC"
                     /locus_tag="RHX21_002614"
     CDS             2344..2973
                     /gene="rplC"
                     /locus_tag="RHX21_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000579825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HDV1987775.1"
                     /translation="MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDG
                     YRAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVELFA
                     DVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKK
                     MAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA"
     gene            2984..3589
                     /gene="rplD"
                     /locus_tag="RHX21_002615"
     CDS             2984..3589
                     /gene="rplD"
                     /locus_tag="RHX21_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010304939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HDV1987776.1"
                     /translation="MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTR
                     AQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYR
                     GALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLA
                     ARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA"
     gene            3586..3888
                     /gene="rplW"
                     /locus_tag="RHX21_002616"
     CDS             3586..3888
                     /gene="rplW"
                     /locus_tag="RHX21_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HDV1987777.1"
                     /translation="MIREERLLKVLRAPHVSEKASTAMEKSNTIVLKVAKDATKAEIK
                     AAVQKLFEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNLDFVGGAE"
     gene            3906..4727
                     /gene="rplB"
                     /locus_tag="RHX21_002617"
     CDS             3906..4727
                     /gene="rplB"
                     /locus_tag="RHX21_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HDV1987778.1"
                     /translation="MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLLEKNSKSGGRN
                     NNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERR
                     YILAPKGLKAGDQIQSGVDAAIKPGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGT
                     YVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRP
                     TVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK"
     gene            4744..5022
                     /gene="rpsS"
                     /locus_tag="RHX21_002618"
     CDS             4744..5022
                     /gene="rpsS"
                     /locus_tag="RHX21_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HDV1987779.1"
                     /translation="MPRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNM
                     IGLTIAVHNGRQHVPVFVTDEMVGHKLGEFAPTRTYRGHAADKKAKKK"
     gene            5037..5369
                     /gene="rplV"
                     /locus_tag="RHX21_002619"
     CDS             5037..5369
                     /gene="rplV"
                     /locus_tag="RHX21_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HDV1987780.1"
                     /translation="METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAA
                     VLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSH
                     ITVVVSDR"
     gene            5387..6088
                     /gene="rpsC"
                     /locus_tag="RHX21_002620"
     CDS             5387..6088
                     /gene="rpsC"
                     /locus_tag="RHX21_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HDV1987781.1"
                     /translation="MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLT
                     KELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQIN
                     IAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGA
                     EIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPE
                     KPAAQPKKQQRKGRK"
     gene            6101..6511
                     /gene="rplP"
                     /locus_tag="RHX21_002621"
     CDS             6101..6511
                     /gene="rplP"
                     /locus_tag="RHX21_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017805229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HDV1987782.1"
                     /translation="MLQPKRTKFRKMHKGRNRGLAQGTDVSFGSFGLKAVGRGRLTAR
                     QIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVL
                     YEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM"
     gene            6511..6702
                     /gene="rpmC"
                     /locus_tag="RHX21_002622"
     CDS             6511..6702
                     /gene="rpmC"
                     /locus_tag="RHX21_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000644743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HDV1987783.1"
                     /translation="MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLK
                     QVRRDVARVKTLLNEKAGA"
     gene            6702..6956
                     /gene="rpsQ"
                     /locus_tag="RHX21_002623"
     CDS             6702..6956
                     /gene="rpsQ"
                     /locus_tag="RHX21_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006817275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HDV1987784.1"
                     /translation="MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKL
                     HVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL"
     gene            7121..7492
                     /gene="rplN"
                     /locus_tag="RHX21_002624"
     CDS             7121..7492
                     /gene="rplN"
                     /locus_tag="RHX21_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015817037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HDV1987785.1"
                     /translation="MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIK
                     EAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIFGP
                     VTRELRSEKFMKIISLAPEVL"
     gene            7503..7817
                     /gene="rplX"
                     /locus_tag="RHX21_002625"
     CDS             7503..7817
                     /gene="rplX"
                     /locus_tag="RHX21_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HDV1987786.1"
                     /translation="MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKK
                     HQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKVRFFKSNSET
                     IK"
     gene            7832..8371
                     /gene="rplE"
                     /locus_tag="RHX21_002626"
     CDS             7832..8371
                     /gene="rplE"
                     /locus_tag="RHX21_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HDV1987787.1"
                     /translation="MAKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAI
                     ADKKLLDNAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFER
                     LITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTA
                     KSDEEGRALLAAFDFPFRK"
     gene            8386..8691
                     /gene="rpsN"
                     /locus_tag="RHX21_002627"
     CDS             8386..8691
                     /gene="rpsN"
                     /locus_tag="RHX21_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005599304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HDV1987788.1"
                     /translation="MAKQSMKAREVKRVALADKYFAKRAELKAIISDVNASDEDRWNA
                     VLKLQTLPRDSSPSRQRNRCRQTGRPHGFLRKFGLSRIKVREAAMRGEIPGLKKASW"
     gene            8725..9117
                     /gene="rpsH"
                     /locus_tag="RHX21_002628"
     CDS             8725..9117
                     /gene="rpsH"
                     /locus_tag="RHX21_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HDV1987789.1"
                     /translation="MSMQDPIADMLTRIRNGQAANKAAVTMPSSKLKVAIANVLKEEG
                     FIEDFKVEGDTKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIA
                     VVSTSKGVMTDRAARQAGLGGEIICYVA"
     gene            9130..9663
                     /gene="rplF"
                     /locus_tag="RHX21_002629"
     CDS             9130..9663
                     /gene="rplF"
                     /locus_tag="RHX21_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003031129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HDV1987790.1"
                     /translation="MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVK
                     HADNTLTFGPRDGYADGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNV
                     INLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGK
                     GVRYADEVVRTKEAKKK"
     gene            9673..10026
                     /gene="rplR"
                     /locus_tag="RHX21_002630"
     CDS             9673..10026
                     /gene="rplR"
                     /locus_tag="RHX21_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005970258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HDV1987791.1"
                     /translation="MDKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNG
                     SEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGR
                     VQALADAAREAGLQF"
     gene            10041..10544
                     /gene="rpsE"
                     /locus_tag="RHX21_002631"
     CDS             10041..10544
                     /gene="rpsE"
                     /locus_tag="RHX21_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004106339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HDV1987792.1"
                     /translation="MAHIEKQAGELQEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNG
                     RVGFGYGKAREVPAAIQKAMEKARRNMINVALNNGTLQHPVKGVHTGSRVFMQPASEG
                     TGIIAGGAMRAVLEVAGVHNVLAKAYGSTNPINVVRATIDGLENMNSPEMVAAKRGKS
                     VEEILGK"
     gene            10548..10727
                     /gene="rpmD"
                     /locus_tag="RHX21_002632"
     CDS             10548..10727
                     /gene="rpmD"
                     /locus_tag="RHX21_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012147215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HDV1987793.1"
                     /translation="MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAI
                     RGMINAVSFMVKVEE"
     gene            10731..11165
                     /gene="rplO"
                     /locus_tag="RHX21_002633"
     CDS             10731..11165
                     /gene="rplO"
                     /locus_tag="RHX21_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011095501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HDV1987794.1"
                     /translation="MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGG
                     GVRRGFEGGQMPLYRRLPKFGFTSRKAAITAEVRLSDLAKVEGGVVDLNTLKAANIIG
                     IQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE"
     gene            11173..12504
                     /gene="secY"
                     /locus_tag="RHX21_002634"
     CDS             11173..12504
                     /gene="secY"
                     /locus_tag="RHX21_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004868351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HDV1987795.1"
                     /translation="MAKQPGLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGI
                     DAAVLAKLLEQQRGTIIEMFNMFSGGALSRASIFALGIMPYISASIIIQLLTVVHPTL
                     AEIKKEGESGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFAFYFTA
                     VVSLVTGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFL
                     VLLLVAVLVFAVTFFVVFVERGQRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIP
                     AIFASSIILFPATIASWFGGGTGWNWLTTISLYLQPGQPLYVLLYASAIIFFCFFYTA
                     LVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLVGALYITFICLIPEFMR
                     DAMKVPFYFGGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKGYGR"
     gene            12536..12652
                     /gene="rpmJ"
                     /locus_tag="RHX21_002635"
     CDS             12536..12652
                     /gene="rpmJ"
                     /locus_tag="RHX21_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020322760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HDV1987796.1"
                     /translation="MKVRASVKKLCRNCKIVKRDGVIRVICSAEPKHKQRQG"
     gene            12799..13155
                     /gene="rpsM"
                     /locus_tag="RHX21_002636"
     CDS             12799..13155
                     /gene="rpsM"
                     /locus_tag="RHX21_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019935869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HDV1987797.1"
                     /translation="MARIAGINIPDHKHAVIALTSIYGVGKTRSKAILAAAGIAEDVK
                     ISELSEGQIDTLRDEVAKFVVEGDLRREISMSIKRLMDLGCYRGLRHRRGLPVRGQRT
                     KTNARTRKGPRKPIKK"
     gene            13172..13561
                     /gene="rpsK"
                     /locus_tag="RHX21_002637"
     CDS             13172..13561
                     /gene="rpsK"
                     /locus_tag="RHX21_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HDV1987798.1"
                     /translation="MAKAPIRARKRVRKQVSDGVAHIHASFNNTIVTITDRQGNALGW
                     ATAGGSGFRGSRKSTPFAAQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNA
                     AGFRITNITDVTPIPHNGCRPPKKRRV"
     gene            13595..14215
                     /gene="rpsD"
                     /locus_tag="RHX21_002638"
     CDS             13595..14215
                     /gene="rpsD"
                     /locus_tag="RHX21_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004410410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HDV1987799.1"
                     /translation="MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQAPGQHGAR
                     KPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVV
                     YRMGFGATRAEARQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALE
                     LAEQREKPTWLEVDAGKMEGTFKRKPERSDLSADINEHLIVELYSK"
     gene            14241..15230
                     /gene="rpoA"
                     /locus_tag="RHX21_002639"
     CDS             14241..15230
                     /gene="rpoA"
                     /locus_tag="RHX21_002639"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005970247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HDV1987800.1"
                     /translation="MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALR
                     RILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTL
                     NKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIH
                     SEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIR
                     RAATILAEQLEAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIH
                     YIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIADE"
     gene            15271..15654
                     /gene="rplQ"
                     /locus_tag="RHX21_002640"
     CDS             15271..15654
                     /gene="rplQ"
                     /locus_tag="RHX21_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HDV1987801.1"
                     /translation="MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKEL
                     RRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGF
                     RAGDNAPMAYIELVDRSEKAEAAAE"
     gene            15761..16129
                     /locus_tag="RHX21_002641"
     CDS             15761..16129
                     /locus_tag="RHX21_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1992 domain-containing protein"
                     /protein_id="HDV1987802.1"
                     /translation="MWLLDQWAERHIAEAQAKGEFDNLAGSGEPLILDDDSHVPPELR
                     AGYRLLKNGGCLPPELEQRREAIQLLDILKGIRHDDPQYQEVSRRLSLLELKLRQAGL
                     STDFLRGDYADKLLNKINDN"
     gene            16140..16565
                     /gene="zntR"
                     /locus_tag="RHX21_002642"
     CDS             16140..16565
                     /gene="zntR"
                     /locus_tag="RHX21_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn(2+)-responsive transcriptional regulator"
                     /protein_id="HDV1987803.1"
                     /translation="MYRIGELAKMAEVTPDTIRYYEKQQMMEHEVRTEGGFRLYTESD
                     LQRLKFIRHARQLGFSLESIRELLSIRIDPEHHTCQESKGIVQERLQEVEARIAELQS
                     MQRSLQRLNDACCGTAHSSVYCSILEALEQGASGVKSGC"
     gene            16621..16839
                     /gene="arfA"
                     /locus_tag="RHX21_002643"
     CDS             16621..16839
                     /gene="arfA"
                     /locus_tag="RHX21_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alternative ribosome-rescue factor ArfA"
                     /protein_id="HDV1987804.1"
                     /translation="MSRYQHTKGQIKDNAIEALLHDPLFRQRVEKNKKGKGSYMRKGK
                     HGNRGNWEASGKKVNHFFTTGLLLSGAC"
     gene            complement(16836..17246)
                     /gene="mscL"
                     /locus_tag="RHX21_002644"
     CDS             complement(16836..17246)
                     /gene="mscL"
                     /locus_tag="RHX21_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large-conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HDV1987805.1"
                     /translation="MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPP
                     LGLLIGGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL
                     NRKKEEPAAAPAPTKEEVLLAEIRDLLKEQNNRS"
     gene            complement(17376..18752)
                     /gene="trkA"
                     /locus_tag="RHX21_002645"
     CDS             complement(17376..18752)
                     /gene="trkA"
                     /locus_tag="RHX21_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004125888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HDV1987806.1"
                     /translation="MKIIILGAGQVGGTLAENLVGENNDITVVDTNGERLRTLQDKFD
                     LRVVQGHGSHPRVLREAGADDADMLVAVTSSDETNMVACQVAYSLFNTPNRIARIRSP
                     DYVRDADKLFHSDAVPIDHLIAPEQLVIDNIYRLIEYPGALQVVNFAEGKVSLAVVKA
                     YYGGPLIGNALSTMREHMPHIDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHI
                     RAVMSELQRLEKPYKRIMLVGGGNIGAGLARRLEKDYSVKLIERNQQRAAELAEKLQN
                     TIVFFGDASDQELLAEEHIDQVDLFIAVTNDDEANIMSAMLAKRMGAKKVMVLIQRRA
                     YVDLVQGSVIDIAISPQQATISALLSHVRKADIVGVSSLRRGVAEAIEAVAHGDESTS
                     RVVGRVIDEIKLPPGTIIGAVVRGNDVMIANDNLRIEQGDHVIMFLTDKKFITDVERL
                     FQPSPFFL"
     gene            complement(18774..20063)
                     /gene="rsmB"
                     /locus_tag="RHX21_002646"
     CDS             complement(18774..20063)
                     /gene="rsmB"
                     /locus_tag="RHX21_002646"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HDV1987807.1"
                     /translation="MKKQRNLRSMAAQAVEQVVEQGQSLSNILPPLQQKVSDKDKALL
                     QELCFGVLRTLSQLDWLINKLMARPMTGKQRTVHYLIMVGLYQLLYTRIPPHAALAET
                     VEGAIAIKRPQLKGLINGVLRQFQRQQEELLAEFNASDARYLHPSWLLKRLQKAYPEQ
                     WQSIVEANNQRPPMWLRVNRTHHSRDSWLALLDEAGMKGFPHADYPDAVRLETPAPVH
                     ALPGFEDGWVTVQDASAQGCMTWLAPQNGEHILDLCAAPGGKTTHILEVAPEAQVVAV
                     DIDEQRLSRVYDNLKRLGMKATVKQGDGRYPSQWCGEQQFDRILLDAPCSATGVIRRH
                     PDIKWLRRDRDIPELAQLQSEILDAIWPHLKSGGTLVYATCSVLPEENSLQIKAFLQR
                     TADAELCETGTPEQPGKQNLPGAEEGDGFFYAKLIKK"
     gene            complement(20109..21056)
                     /gene="fmt"
                     /locus_tag="RHX21_002647"
     CDS             complement(20109..21056)
                     /gene="fmt"
                     /locus_tag="RHX21_002647"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HDV1987808.1"
                     /translation="MSESLRIIFAGTPDFAARHLDALLSSGHNVVGVFTQPDRPAGRG
                     KKLMPSPVKVLAEEKGLPVFQPVSLRPQENQQLVADLQADVMVVVAYGLILPKAVLEM
                     PRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDVGLDTGDMLYKLSCPIT
                     AEDTSGTLYDKLAELGPQGLITTLKQLADGTAKPEVQDETLVTYAEKLSKEEARIDWS
                     LSAAQLERCIRAFNPWPMSWLEIEGQPVKVWKASVIDTATNAAPGTILEANKQGIQVA
                     TGDGILNLLSLQPAGKKAMSAQDLLNSRREWFVPGNRLV"
     gene            complement(21071..21580)
                     /gene="def"
                     /locus_tag="RHX21_002648"
     CDS             complement(21071..21580)
                     /gene="def"
                     /locus_tag="RHX21_002648"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDV1987809.1"
                     /translation="MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEG
                     IGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVP
                     RAEKVKIRALDRDGKPFELEADGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVE
                     KLDRLKARA"
     gene            21710..22834
                     /gene="dprA"
                     /locus_tag="RHX21_002649"
     CDS             21710..22834
                     /gene="dprA"
                     /locus_tag="RHX21_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HDV1987810.1"
                     /translation="MVDTEIWLRLMSISSLYGDDMVRIAHWLAKQSQIDAVGLQQTGL
                     TLRQAQRFLSFPRKSIESSLCWLEQPNHHLIPADSEFYPPQLLVTTDYPGALFVEGEL
                     HALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
                     GVSIAVLGNGLNTIHPRRHARLAASLLEHGGALVSEFPLDVPPLAYNFPRRNRIISGL
                     SKGVLVVEAALRSGSLVTARCALEQGREVFALPGPIGNPGSEGPHWLIKQGAILVTEP
                     EEILENLQFGLHWLPDAPENSFYSPDQQDVALPFPELLANVGDEVTPVDVVAERAGQP
                     VPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV"
     gene            22806..23279
                     /locus_tag="RHX21_002650"
     CDS             22806..23279
                     /locus_tag="RHX21_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF494 domain-containing protein"
                     /protein_id="HDV1987811.1"
                     /translation="MFDVLMYLFETYIHTEAELRVDQDKLEQDLTDAGFDREDIYNAL
                     LWLEKLADYQEGLAEPMQLASDPLSMRIYTPEECERLDASCRGFLLFLEQIQVLNLET
                     REMVIERVLALDTAEFDLEDLKWVILMVLFNIPGCENAYQQMEELLFEVNEGMLH"
     gene            23308..23850
                     /locus_tag="RHX21_002651"
     CDS             23308..23850
                     /locus_tag="RHX21_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /protein_id="HDV1987812.1"
                     /translation="MAKSALFTVRNNESCPKCGAELVIRSGKHGPFLGCSQYPACDYV
                     RPLKSSADGHIVKVLEGQVCLACGANLVLRQGRFGMFIGCSNYPECEHTELIDKPDET
                     AITCPQCRTGHLVQRRSRYGKTFHSCDRYPECQFAINFKPIAGECPECHYPLLIEKKT
                     AQGVKHFCASKQCGKPVSAE"
     gene            23855..24427
                     /gene="tsaC"
                     /locus_tag="RHX21_002652"
     CDS             23855..24427
                     /gene="tsaC"
                     /locus_tag="RHX21_002652"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase type 1
                     TsaC"
                     /protein_id="HDV1987813.1"
                     /translation="MNNNLQGDAIAAAIDVLNEERVIAYPTEAVFGVGCDPDSETAVM
                     RLLELKQRPVDKGLILIAANYEQLKPYIDDTMLTDAQRETIFSRWPGPVTFVFPAPAT
                     TPRWLTGRFDSLAVRVTDHPLVVALCQAYGKPLVSTSANLSGLPPCRTVDEVRAQFGA
                     AFPVVPGETGGRLNPSEIRDALTGELFRQG"
     gene            24432..25250
                     /gene="aroE"
                     /locus_tag="RHX21_002653"
     CDS             24432..25250
                     /gene="aroE"
                     /locus_tag="RHX21_002653"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDV1987814.1"
                     /translation="METYAVFGNPIAHSKSPFIHQQFAQQLNIEHPYGRVLAPINDFI
                     NTLNAFFRAGGKGANVTVPFKEEAFARADELTERAALAGAVNTLKRLEDGRLLGDNTD
                     GIGLLSDLERLSFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTVSRAEELAK
                     LFAHTGSIQALGMDELEGHEFDLIINATSSGISGDIPAIPSSLIHPGIYCYDMFYQKG
                     KTPFLAWCEQRGSKRNADGLGMLVAQAAHAFLLWHGVLPDVEPVIKQLQEELSA"
     gene            25247..25504
                     /locus_tag="RHX21_002654"
     CDS             25247..25504
                     /locus_tag="RHX21_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1488 domain-containing protein"
                     /protein_id="HDV1987815.1"
                     /translation="MNQAIQFPDREEWDENKKCVCFPALVNGMQLTCAISGESLAYRF
                     TGDTPEQWLASFRQHRWDLEEEAENLIQEQSEDDQGWVWLP"
     gene            complement(25480..26034)
                     /locus_tag="RHX21_002655"
     CDS             complement(25480..26034)
                     /locus_tag="RHX21_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417738.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HDV1987816.1"
                     /translation="MSDVLRPYRDLFPQIGQRVMIDDSSVVIGDVRLADDVGIWPLVV
                     IRGDVHYVQIGARTNIQDGSMLHVTHKSSYNPDGNPLTIGEDVTVGHKVMLHGCTIGN
                     RVLVGMGSILLDGAIVEDDVMIGAGSLVPQNKRLESGYLYLGSPVKQIRPLSDEEKAG
                     LRYSANNYVKWKDEYLDQGNQTQP"
BASE COUNT         6727 a         6244 c         6825 g         6477 t
ORIGIN      
        1 cgtcatactc cgttcttcaa aggctaccgt ccgcagttct acttccgtac tactgacgtg
       61 actggtacca tcgaactgcc ggaaggcgta gagatggtaa tgccgggcga caacatcaaa
      121 atggttgtta ccctgatcca cccgatcgcg atggacgacg gtctgcgttt cgcaatccgt
      181 gaaggcggcc gtaccgttgg cgcgggcgtt gttgctaaag ttctgggcta attacacgtt
      241 aattagtttt gaattgaaaa gggcgcttcg gcgccctttt tgctgcccgt aatttgagct
      301 cgaaatattt agtcgtaatt ttgctcgctg aactatggcg caaataaaac tgtgctattg
      361 taatcataac cattctcatt tacgctttgc gcagaatttg aacgggagca atcatgtacg
      421 tttgtttgtg taatggtgta agtgacaaaa aaattcgcca ggcagtccgt cagtttcatc
      481 cgcaatcttt ccaacaattg cgtaagttta ttcctgtggg aaatcaatgc ggtaagtgca
      541 ttcgcgccgc gcgcgaagtg atgcaggacg agttgatgca gatgccagaa tttaaagaga
      601 ttgcctgaag accacgctta ttttttgaca tcccgctagc cccatctacg ctctaatagt
      661 ggaagcggag ggactataaa atgaaaggtg atgttaaaat cataaattat ctcaataaac
      721 tattgggaaa tgagcttgtc gcaatcaatc agtattttct ccatgcccgg atgtttaaaa
      781 actggggcct gatgcgtctc aatgacgtcg aataccatga atccatcgat gagatgaaac
      841 acgctgataa atatatcgag cgtattttgt ttttagaagg aatccccaac ttacaggatt
      901 taggcaaact ggggattggt gaagatgtcg aggagatgct gcaatccgac ctgcgattag
      961 aactggaagg cgcgaaggat ctccgtgagg ctatcgcgta tgccgacagc gttcatgact
     1021 atgttagccg tgatatgatg atcgagatcc ttgccgatga agaaggtcat attgactggc
     1081 tcgaaactga gctggatctc atcggtaaaa tcggtttaca aaattacctg caatcacaaa
     1141 taaaagttaa agattaacgg cctgccagca aactatccca acctacaacg aaacccgcag
     1201 ccgccagaaa tggcccaaac ggcagcgggt tttttaatga ctcttttcct ctcatgagca
     1261 gaccaacaac tacggctccg caagcgaatg aggcagcaag gaaaaccagt cgtggcaaga
     1321 aggtccaggt atgccaggca ccaagggcgg cgagaaactt cacatcacca tagcctaatc
     1381 cttctttatg acgcagtatg cgataccccc agtaaatgac agcgaatgtg ccgtaaccaa
     1441 taatcgcccc ccataacgca tcggctaaac cgtcaggatt acaaacctga gagaacaaaa
     1501 gacctgacca gagtaacggg caggtaaatc tgtcaggtaa caagccatgc tttgcatccc
     1561 ataaaaaaag taggacagat aaacaagcgt acaaaatcag aaagggaagg gtagcgtcca
     1621 taaaacatcc tctgtaattg gagtatcacc atcgaataac tccggatgct cagcaacaga
     1681 gaaatcgctg atttgttaac ctggttccgg tgaaaaacgc tatcttcaca accttacaaa
     1741 tttcgtggaa tacagctcgc aatctgcgcg ttgcgattaa tttctacccg atgcttgcgt
     1801 caggctcaga tttgcgtata atgcgcgggc ttgtcgtagt tgacagcagg ttcaatctga
     1861 acctcagtta gccgaatttg gctacctaac aatgctccca atcggggagc tacgtaagaa
     1921 cggttacact ctcccatcaa tcgtaatggg tctgaggagt aatcattttc gtttataaaa
     1981 taattggagc tctggtctca tgcagaacca aagaatccgt atccgcctga aagcgtttga
     2041 tcatcgtctg atcgatcaag caaccgcgga aatcgtcgag actgccaagc gcactggtgc
     2101 gcaggtccgt ggtccgatcc cgctgccgac acgcaaagag cgcttcactg ttctgatctc
     2161 cccgcacgtc aacaaagacg cgcgcgatca gtacgaaatc cgtactcact tgcgtctggt
     2221 tgacatcgtt gagccaaccg agaaaaccgt tgatgctctg atgcgtctgg atctggctgc
     2281 cggtgtagac gtgcagatca gcctgggtta atcaggtcat tgagcgattg agaggttgaa
     2341 acaatgattg gtttagtcgg taaaaaagtg ggtatgaccc gtatcttcac agaagacggc
     2401 gtttctatcc cagtaaccgt aatcgaagtt gaagcaaacc gcgttactca ggttaaagac
     2461 ctggctaacg atggctaccg tgctattcag gtgaccaccg gtgctaaaaa agctaaccgt
     2521 gtgaccaagc ctgaagctgg ccacttcgct aaagctggcg tagaagctgg ccgtggtctg
     2581 tgggaattcc gcctggctga aggcgaagag ttcactgtag gtcagagcat tagcgttgaa
     2641 ctgtttgctg acgttaaaaa agttgacgta actggcacct ctaaaggtaa aggtttcgca
     2701 ggtaccgtta agcgctggaa cttccgtacc caggacgcta ctcacggtaa ctccttgtct
     2761 caccgcgttc cgggttctat cggtcagaac cagactccgg gcaaagtgtt caaaggcaag
     2821 aaaatggcag gtcagatggg taacgaacgt gtaaccgttc agagccttga cgtagtacgc
     2881 gttgacgctg agcgcaacct gctgctggtt aaaggtgctg tcccgggtgc aaccggtagc
     2941 gacctgatcg ttaaaccagc tgtgaaggcg taaggagata gcaatggaat tagtattgaa
     3001 agacgcgcag agcgcgctga ctgtttccga aactaccttc ggtcgtgatt tcaacgaagc
     3061 gctggttcac caggttgttg ttgcttatgc agctggtgct cgtcagggta ctcgtgctca
     3121 gaagactcgt gctgaagtaa ctggttccgg taaaaaaccg tggcgccaga aaggcaccgg
     3181 ccgtgcgcgt tctggttcta tcaagagccc gatctggcgt tctggtggcg tgacctttgc
     3241 tgctcgtccg caggaccaca gtcaaaaagt taacaagaag atgtaccgcg gcgcgctgaa
     3301 aagcatcctg tccgaactgg tacgtcagga tcgtctgatc gttgtcgaga agttctctgt
     3361 agaagcgccg aaaactaagc tgctggcaca gaaactgaaa gacatggctc tggaagatgt
     3421 gctgatcatc accggtgagc tggacgaaaa cctgttcctg gctgcgcgca acctgcacaa
     3481 ggttgacgta cgcgatgcaa ctggtatcga cccggttagc ctgatcgcct tcgacaaagt
     3541 cgtaatgact gctgatgctg ttaagcaagt tgaggagatg ctggcatgat tcgtgaagaa
     3601 cgtctgctga aggtgctgcg tgcaccgcac gtttctgaaa aagcgtctac tgcgatggaa
     3661 aaatccaaca ccatcgtact caaagttgct aaagacgcga ccaaagcaga aatcaaagct
     3721 gctgtgcaga aactgtttga agtcgaagtc gaagtcgtta acaccctggt agttaaaggg
     3781 aaagttaaac gtcacggaca gcgtatcggt cgtcgtagcg actggaaaaa agcttacgtc
     3841 accctgaaag aaggccagaa tctggacttc gttggcggcg ctgagtaagt cggaggagta
     3901 atacaatggc agttgttaaa tgtaaaccga catctccggg tcgtcgccac gtagttaaag
     3961 tggttaaccc tgagctgcac aagggcaaac cttttgctcc gttgctggaa aaaaacagca
     4021 aatccggtgg tcgtaacaac aatggccgta tcaccactcg tcatatcggt ggtggccaca
     4081 agcaggctta ccgtattgtt gacttcaaac gcaacaaaga cggtatcccg gcagttgttg
     4141 aacgtcttga gtacgatccg aaccgttccg cgaacatcgc gctggttctg tacaaagacg
     4201 gtgaacgccg ttacatcctg gcccctaaag gcctgaaagc tggcgaccag attcagtctg
     4261 gcgttgatgc tgcaatcaaa ccaggtaaca ccctgccgat gcgcaacatc ccggttggtt
     4321 ctactgttca taacgtagaa atgaaaccag gtaaaggcgg tcagctggca cgttccgctg
     4381 gtacttacgt tcagatcgtt gctcgtgatg gtgcttatgt caccctgcgt ctgcgttctg
     4441 gtgaaatgcg taaagtagaa gcagactgcc gtgcaactct gggcgaagtt ggcaatgctg
     4501 agcatatgct gcgcgttctg ggtaaagcag gtgctgcacg ctggcgtggt gttcgtccga
     4561 ccgttcgcgg taccgcgatg aacccggtag accacccaca tggtggtggt gaaggtcgta
     4621 actttggtaa gcacccggta actccgtggg gcgttcagac caaaggtaag aagacccgca
     4681 gcaacaagcg tactgataaa ttcatcgtac gtcgccgtag caaataattt tagaggataa
     4741 gccatgccac gttctctcaa gaaaggtcct tttattgacc tgcacttgct gaagaaggta
     4801 gagaaagcgg tggaaagcgg agacaagaag cccctgcgca cttggtcccg tcgttcaacg
     4861 atctttccta acatgatcgg tttgaccatc gctgtccata atggtcgtca gcacgttccg
     4921 gtatttgtaa ccgacgaaat ggtcggtcac aaactgggtg aattcgcacc gactcgtact
     4981 tatcgcggcc acgctgctga taaaaaagcg aagaagaaat aaggtaggag gaagagatgg
     5041 aaactatcgc taaacatcgc catgctcgtt cttctgctca gaaggttcgc cttgttgctg
     5101 acctgattcg cggtaagaaa gtgtcgcagg ctctggatat tttgacctac accaacaaga
     5161 aagcggctgt actggtcaag aaagttctgg aatctgccat tgctaacgct gaacacaacg
     5221 atggcgctga cattgacgat ctgaaagtta cgaaaatttt cgtagacgaa ggcccgagca
     5281 tgaagcgcat tatgccgcgt gcaaaaggtc gtgcagatcg catcctgaag cgcaccagcc
     5341 acatcactgt ggttgtgtcc gatcgctgag actctggaga ctagcaatgg gtcagaaagt
     5401 acatcctaat ggtattcgcc tgggtattgt aaaaccatgg aactctacct ggtttgcgaa
     5461 caccaaagaa ttcgctgaca acctggacag cgattttaaa gtacgtcagt acctgactaa
     5521 ggaactggct aaagcgtccg tatctcgtat cgttatcgag cgtccggcta agagcatccg
     5581 tgtaaccatt cacactgctc gcccgggtat cgttatcggt aaaaaaggtg aagacgtaga
     5641 aaaactgcgt aaggtcgtag cggacatcgc tggcgttcct gcacagatca acatcgccga
     5701 agttcgtaag cctgaactgg acgcaaaact ggttgctgac agcatcactt ctcagctgga
     5761 acgtcgcgtt atgttccgtc gtgctatgaa gcgtgctgta cagaacgcaa tgcgtctggg
     5821 cgctaaaggt attaaagttg aagttagcgg ccgtctgggc ggcgcggaaa tcgcacgtac
     5881 cgaatggtac cgcgaaggtc gcgtaccgct gcacactctg cgtgctgaca tcgactacaa
     5941 cacctctgaa gcgcacacca cttacggtgt aatcggcgtt aaagtgtgga tcttcaaagg
     6001 cgagatcctg ggtggtatgg ctgctgttga acaaccggaa aaaccggctg ctcagcctaa
     6061 aaagcagcag cgtaaaggcc gtaaataagg agcgtcgctg atgttacaac caaagcgtac
     6121 aaaattccgt aaaatgcaca aaggccgtaa ccgcggtctg gcgcagggta cggatgttag
     6181 cttcggcagc ttcggtctga aagctgttgg ccgtggtcgt ctgactgccc gtcagatcga
     6241 agcagcacgt cgtgctatga cccgtgcagt taagcgtcaa ggtaagatct ggatccgtgt
     6301 gttcccggac aaaccgatca ctgaaaagcc gctggcagtg cgtatgggta aaggtaaagg
     6361 taacgtggag tattgggttg ccttgattca gccgggtaaa gtcctgtatg aaatggacgg
     6421 tgttccggaa gagctggccc gtgaagcatt caagctggca gcagcgaaac tgccgattaa
     6481 aaccaccttt gtaactaaga cggtgatgta atgaaagcaa aagagctgcg tgagaagagc
     6541 gttgaagagc tgaacaccga gctgctgaac ctgctgcgtg agcagttcaa cctgcgtatg
     6601 caggctgcaa gtggccagct gcaacagtct cacctgttga agcaagtgcg tcgcgatgtc
     6661 gcacgcgtta agactttact gaacgagaag gcgggtgcgt aatgaccgat aaaatccgta
     6721 ctctgcaagg tcgcgttgtt agcgacaaaa tggagaaatc cattgttgtt gctatcgaac
     6781 gttttgtgaa acacccgatc tacggtaaat tcatcaagcg tacgaccaaa ctgcacgtac
     6841 atgacgagaa caacgaatgc ggtatcggtg acgtggttga aatccgcgaa tgccgtccgc
     6901 tgtccaagac taaatcctgg acgctggttc gcgttgtaga gaaagcggtt ctgtaataca
     6961 gtacactctc tcgatacgaa taaacggctc agaaatgagc cgtttatttt ttctacccat
     7021 atccttgaag cggtgttata atgccgcgcc ctcgatatgg ggatttttaa cgacctgatt
     7081 ttcgggtctc agtagtagtt gacattagcg gagcactaaa atgatccaag aacagactat
     7141 gctgaacgtc gccgacaact ccggtgcacg tcgcgtaatg tgtatcaagg ttctgggtgg
     7201 ctcgcaccgt cgctacgcag gcgtaggcga catcatcaag atcaccatca aagaagcaat
     7261 tccgcgtggt aaggtcaaaa aaggtgatgt gctgaaggcg gtagtggtgc gcaccaagaa
     7321 gggtgttcgt cgcccggacg gttctgtcat tcgcttcgat ggtaatgctt gtgttcttct
     7381 gaacaacaac agcgagcagc ctatcggtac gcgtattttt gggccggtaa ctcgtgagct
     7441 tcgtagtgag aagttcatga aaattatctc tctggcacca gaagtactct aaggagcgaa
     7501 tcatggcagc gaaaatccgt cgtgatgacg aagttatcgt gttaaccggt aaagataaag
     7561 gtaaacgcgg taaagttaag aatgtcctgt cttccggcaa ggtcattgtt gaaggtatca
     7621 acctggttaa gaaacatcag aagccggttc cggccctgaa ccaaccgggt ggcatcgttg
     7681 aaaaagaagc cgctattcag gtttccaacg tagcaatctt caatgcggca accggcaagg
     7741 ctgaccgtgt aggctttaga ttcgaagacg gcaaaaaagt ccgtttcttc aagtctaaca
     7801 gcgaaactat caagtaattt ggagtagtac gatggcgaaa ctgcatgatt actacaaaga
     7861 cgaagtagtt aaaaaactca tgactgagtt taactacaat tctgtcatgc aagtccctcg
     7921 ggtcgagaag atcaccctga acatgggtgt tggtgaagcg atcgctgaca aaaaactgct
     7981 ggataacgca gcagcagacc tggcagcaat ctccggtcaa aaaccgctga tcaccaaagc
     8041 acgcaaatct gttgcaggct tcaaaatccg tcagggctat ccgatcggct gtaaagtaac
     8101 tctgcgtggc gaacgcatgt gggagttctt tgagcgcctg atcactattg ctgtacctcg
     8161 tatccgtgac ttccgtggcc tgtccgctaa gtctttcgac ggtcgtggta actacagcat
     8221 gggtgtccgt gagcagatca tcttcccaga aatcgactac gataaagtcg accgcgttcg
     8281 tggtttggat attaccatta ccactactgc gaaatctgac gaagaaggcc gcgctctgct
     8341 ggctgccttt gacttcccgt tccgcaagta aggtagggtt actaaatggc taagcaatca
     8401 atgaaagcac gcgaagtaaa acgcgtagct ttagctgata aatacttcgc gaaacgcgct
     8461 gaactgaaag cgatcatctc tgatgtgaac gcttccgacg aagatcgttg gaacgctgtt
     8521 ctcaagctgc agactctgcc gcgtgattcc agcccgtctc gtcagcgtaa ccgctgccgt
     8581 caaacaggtc gtccgcatgg tttcctgcgg aagttcgggt tgagccgtat taaggtccgt
     8641 gaagccgcta tgcgcggtga aatcccgggt ctgaaaaagg ctagctggta attgtcacca
     8701 attgaatcac gggagtaaag acagatgagc atgcaagatc cgatcgcgga tatgctgacc
     8761 cgtatccgta acggtcaggc cgcgaacaaa gctgcggtca ccatgccttc ctccaagctg
     8821 aaagtggcaa tcgccaacgt gctgaaggaa gaaggtttta ttgaagattt taaagttgaa
     8881 ggcgacacca agcctgaact ggaacttact ctgaagtatt tccagggcaa agctgttgta
     8941 gaaagcattc agcgtgtcag ccgcccaggt ctgcgcatct ataaacgtaa agatgagctg
     9001 ccgaaagtta tggcgggtct gggtatcgca gttgtttcta cctctaaagg tgttatgact
     9061 gatcgtgcag cgcgccaggc tggtcttggt ggcgaaatta tctgctacgt agcctaatcg
     9121 gaggaaaaaa tgtctcgtgt tgctaaagca ccggtcgttg ttcctgccgg cgttgacgta
     9181 aaaatcaacg gtcaggttat tacgatcaaa ggtaaaaacg gcgagctgac tcgtactctc
     9241 aacgatgctg ttgaagttaa acatgcagat aataccctga ccttcggtcc gcgtgatggt
     9301 tacgcagacg gttgggcaca ggctggtacc gcgcgtgccc tgctgaactc aatggttatc
     9361 ggtgttaccg aaggcttcac taagaagctg cagctggttg gtgtaggtta ccgtgcagcg
     9421 gttaaaggta atgtgattaa cctgtctctg ggtttctctc atcctgttga ccatcagctg
     9481 cctgcgggta tcactgctga atgtccgact cagactgaaa tcgtgctgaa aggcgctgat
     9541 aagcaggtga tcggccaggt tgcagcggat ctgcgcgcct accgtcgtcc tgagccttat
     9601 aaaggcaagg gtgttcgtta cgccgacgaa gtcgtgcgta ccaaagaggc taagaagaag
     9661 taaggtaaca ctatggataa gaaatctgct cgtatccgtc gtgcgacccg cgcacgccgc
     9721 aagctccagg agctgggcgc aactcgcctg gtggtacatc gtaccccgcg tcacatttac
     9781 gcacaggtaa ttgcaccgaa cggttctgaa gttctggtag ctgcttctac tgtagaaaaa
     9841 gctatcgctg aacaactgaa gtacaccggt aacaaagacg cggctgcagc tgtgggtaaa
     9901 gctgtcgctg aacgcgctct ggaaaaaggc atcaaagatg tatcctttga ccgttccggg
     9961 ttccaatatc atggtcgtgt ccaggcactg gcagatgctg cccgtgaagc tggccttcag
    10021 ttctaaggta gaggtgtaag atggctcaca tcgaaaaaca agctggcgaa ctgcaggaaa
    10081 agctgatcgc ggtaaaccgc gtatctaaaa ccgttaaagg tggtcgtatt ttctccttca
    10141 cagctctgac tgtagttggc gatggtaacg gtcgcgttgg ttttggttac ggtaaagcgc
    10201 gtgaagttcc agcagcgatc cagaaagcga tggaaaaagc ccgtcgcaat atgattaacg
    10261 tcgcgctgaa taacggcact ctgcaacacc ctgttaaagg tgttcacacg ggttctcgcg
    10321 tattcatgca gccggcttcc gaaggtaccg gtatcatcgc cggtggtgca atgcgcgccg
    10381 ttctggaagt cgctggggtt cataacgttc tggctaaagc atatggttcc accaacccga
    10441 tcaacgtggt tcgtgcaact attgatggcc tggaaaatat gaattctcca gaaatggtcg
    10501 ctgccaagcg tggtaaatcc gttgaagaaa ttctggggaa ataaaccatg gcaaagacta
    10561 ttaaaattac tcaaacccgc agtgcaatcg gtcgtctgcc gaaacacaag gcaacgctgc
    10621 ttggcctggg tctgcgtcgt attggtcaca ccgtagagcg cgaggatact cctgctattc
    10681 gcggtatgat caacgcggtt tccttcatgg ttaaagttga ggagtaagag atgcgtttaa
    10741 atactctgtc tccggccgaa ggctccaaaa aggcgggtaa acgcctgggt cgtggtatcg
    10801 gttctggcct cggtaaaacc ggtggtcgtg gtcacaaagg tcagaaatct cgttctggcg
    10861 gtggcgtacg tcgcggtttc gagggtggtc agatgcctct gtaccgtcgt ctgccgaaat
    10921 tcggcttcac ttctcgtaaa gcagcgatta cagccgaagt tcgtctgtct gacctggcta
    10981 aagtagaagg cggtgttgta gacctgaaca cgctgaaagc ggctaacatt atcggtatcc
    11041 agatcgagtt cgcgaaagtg atcctggctg gcgaagtaac gactccggta actgttcgtg
    11101 gcctgcgtgt tactaaaggc gctcgtgctg ctatcgaagc tgctggcggt aaaatcgagg
    11161 aataagtagc agatggctaa acaaccggga ttagattttc aaagtgccaa aggtggctta
    11221 ggcgagctga aacgcagact gctgtttgtt atcggtgcgc tgattgtgtt ccgtattggc
    11281 tcttttattc cgatccctgg tattgatgcc gctgtacttg ccaaactgct tgagcaacag
    11341 cgaggcacca tcattgagat gtttaacatg ttctctggtg gtgctctcag ccgtgcttct
    11401 atctttgctc tggggatcat gccgtatatt tcggcgtcga tcattatcca gctgctgacg
    11461 gtggttcacc caacgttggc agaaattaag aaagaagggg agtctggtcg tcgtaagatc
    11521 agccagtaca cccgttacgg tactctggtg ctggcaatat tccagtcgat cggtattgct
    11581 accggtctgc cgaatatgcc tggtatgcaa ggcctggtga ttaacccagg ctttgcattc
    11641 tacttcaccg ctgttgtaag tctggtcaca ggaacgatgt tcctgatgtg gttgggcgaa
    11701 cagattactg aacgaggtat cggcaacggt atttcaatca ttatcttcgc cggtattgtc
    11761 gcgggactcc cgccagccat tgcccatact atcgagcaag cgcgtcaagg cgacctgcac
    11821 ttcctcgtgt tgctgttggt tgcagtatta gtatttgcag tgacgttctt tgttgtattt
    11881 gttgagcgtg gtcaacgccg cattgtggta aactacgcga aacgtcagca aggtcgtcgt
    11941 gtctatgctg cacagagcac acatttaccg ctgaaagtga atatggcggg ggtaatcccg
    12001 gcaatcttcg cttccagtat tattctgttc ccggcgacca tcgcgtcatg gttcgggggc
    12061 ggtactggtt ggaactggct gacaacaatt tcgctgtatt tgcagcctgg gcaaccgctt
    12121 tatgtgttac tctatgcgtc tgcaatcatc ttcttctgtt tcttctacac ggcgttggtt
    12181 ttcaacccgc gtgaaacagc agataacctg aagaagtccg gtgcatttgt accaggaatt
    12241 cgtccgggag agcaaacggc gaagtatatc gataaagtaa tgacccgcct gaccctggtt
    12301 ggtgcgctgt atattacctt tatctgcctg atcccggagt tcatgcgtga tgcaatgaaa
    12361 gtaccgttct acttcggtgg gacctcactg cttatcgttg ttgtcgtgat tatggacttt
    12421 atggctcaag tgcaaactct gatgatgtcc agtcagtatg agtctgcatt gaagaaggcg
    12481 aacctgaaag gctacggccg ataattggtc gcccgagaag ttacggagag taaaaatgaa
    12541 agttcgtgct tccgtcaaga aattatgccg taactgcaaa atcgttaagc gtgatggtgt
    12601 catccgtgtg atttgcagtg ccgagccgaa gcataaacag cgccaaggct gattttttcg
    12661 catatttttc ttgcaaagtt gggttgagct ggctagatta gccagccaat cttttgtatg
    12721 tctgtgcgtt tccatttgag tatcctgaaa acgggctttt cagcatggaa cgtacatatt
    12781 aaatagtagg agtgcatagt ggcccgtata gcaggcatta acattcctga tcataagcat
    12841 gccgtaatcg cattaacttc gatttatggc gtcggcaaga cccgttctaa agccatcctg
    12901 gctgcagcgg gtatcgctga agatgttaag atcagtgagc tgtctgaagg acaaatcgac
    12961 acgctgcgtg acgaagttgc caaatttgtc gttgaaggtg atctgcgccg tgaaatcagc
    13021 atgagcatca agcgcctgat ggatcttggt tgctatcgcg gtttgcgtca tcgtcgtggt
    13081 ctcccggttc gcggtcagcg taccaagacc aacgcacgta cccgtaaggg tccgcgcaaa
    13141 ccgatcaaga aataatcggg gtgattgaat aatggcaaag gcaccaattc gtgcacgtaa
    13201 acgtgtaaga aaacaagtct ctgacggcgt ggctcatatc catgcttctt tcaacaacac
    13261 catcgtgact atcactgatc gtcagggtaa cgcgttgggt tgggcaacag ccggtggttc
    13321 cggtttccgt ggttctcgca aatccactcc gtttgcagct caggttgcag cagagcgttg
    13381 cgctgacgcc gtgaaagaat acggcatcaa gaatctggaa gttatggtta aaggtccggg
    13441 tccaggccgc gaatctacta ttcgtgctct gaacgccgca ggtttccgca tcactaatat
    13501 tactgatgtg actccgatcc ctcataacgg ttgtcgtccg ccgaaaaaac gtcgcgtata
    13561 acgcctcgtt ttccaggttt gttggagaaa gaaaatggca agatatttgg gtcctaagct
    13621 caagctgagc cgtcgtgagg gcaccgactt attccttaag tctggcgttc gcgcgatcga
    13681 taccaagtgt aaaattgaac aagctcctgg ccagcacggt gcgcgtaaac cgcgtctgtc
    13741 tgactatggt gtgcagttgc gtgaaaagca aaaagttcgc cgtatctatg gtgtgctgga
    13801 gcgtcagttc cgtaactact acaaagaagc agcacgtctg aaaggcaaca ccggtgaaaa
    13861 cctgttggct ctgctggaag gtcgtctgga caacgttgta taccgtatgg gcttcggtgc
    13921 cactcgtgca gaagcacgtc agctggttag ccataaagca attatggtaa acggtcgtgt
    13981 tgttaacatc gcttcttatc aggttagtcc gaatgacgtt gtaagcattc gtgagaaagc
    14041 gaagaagcag tctcgcgtga aagccgctct ggagctggct gagcagcgtg aaaagccaac
    14101 ctggctggaa gttgatgctg gcaagatgga aggtacgttt aagcgtaagc cggagcgttc
    14161 tgatctgtct gcggacatta acgaacacct gatcgtcgag ctttactcca agtaaagctt
    14221 agtaccaaag agaggacaca atgcagggtt ctgtgacaga gtttctaaaa ccgcgcctgg
    14281 ttgatatcga gcaagtgagt tcgacgcacg ccaaggtgac ccttgagcct ttagagcgtg
    14341 gctttggcca tactctgggt aacgcactgc gccgtattct gctctcatcg atgccgggtt
    14401 gcgcggtgac cgaggttgag attgatggtg tactacatga gtacagcacc aaagaaggcg
    14461 ttcaggaaga tatcctggaa atcctgctca acctgaaagg gctggcggtg agagttcagg
    14521 gcaaagatga agttattctt accttgaata aatctggcat tggccctgtg actgcagccg
    14581 atatcaccca cgacggtgat gtcgaaatcg tcaagccgca gcacgtgatc tgccacctga
    14641 ccgatgagaa cgcgtctatt agcatgcgta tcaaagttca gcgcggtcgt ggttatgtgc
    14701 cggcttctac ccgaattcat tcggaagaag atgagcgccc aatcggccgt ctgctggtcg
    14761 acgcatgcta cagccctgtg gagcgtattg cctacaatgt tgaagcagcg cgtgtagaac
    14821 agcgtaccga cctggacaag ctggtcatcg aaatggaaac caacggcaca atcgatcctg
    14881 aagaggcgat tcgtcgtgcg gcaaccattc tggctgaaca actggaagct ttcgttgact
    14941 tacgtgatgt acgtcagcct gaagtgaaag aagagaaacc agagttcgat ccgatcctgc
    15001 tgcgccctgt tgacgatctg gaattgactg tccgctctgc taactgcctt aaagcagaag
    15061 ctatccacta tatcggtgat ctggtacagc gtaccgaggt tgagctcctt aaaacgccta
    15121 accttggtaa aaaatctctt actgagatta aagacgtgct ggcttcccgt ggactgtctc
    15181 tgggcatgcg cctggaaaac tggccaccgg caagcatcgc tgacgagtaa ccggatcaca
    15241 ggttaaggtt ttactgagaa ggataaggtc atgcgccatc gtaagagtgg tcgtcaactg
    15301 aaccgcaaca gcagccatcg ccaggctatg ttccgcaata tggcaggttc actggttcgt
    15361 catgaaatca tcaagacgac tctgcctaaa gcgaaagagc tgcgccgcgt agttgagccg
    15421 ctgattactc ttgccaagac tgatagcgtt gctaatcgtc gtctggcatt cgcccgtact
    15481 cgtgataacg agatcgtggc aaaactgttt aacgaactgg gcccgcgttt cgcgagccgt
    15541 gccggtggtt acactcgtat tctgaagtgt ggcttccgtg caggcgacaa cgcgccgatg
    15601 gcttacatcg agctggttga tcgttcagag aaagcagaag ctgctgcaga gtaatctgaa
    15661 gcaacgtaaa aaaacccgcc ccggcgggtt tttttatacc cgtagcatcc ccacttatct
    15721 acaatagctg tactcttttt gttcatcccc tggagtatat atgtggttac ttgaccagtg
    15781 ggcagagcgt catatagcag aagcgcaagc gaaaggtgag tttgataacc tggcaggtag
    15841 cggcgaacca ttgatactgg atgatgattc tcacgtgcca ccggaattac gtgcggggta
    15901 tcgcttgttg aagaatggcg gttgcttacc gccagaactt gagcaacgga gggaagcaat
    15961 tcagcttctg gatattctca aaggtatccg tcacgatgat ccgcaatatc aagaggttag
    16021 ccgtcgattg tcattactgg aattgaagct gcgacaagct ggactgagta ccgatttttt
    16081 acgcggcgat tatgctgaca agttgttgaa taaaatcaac gataactagt ggagtatgta
    16141 tgtatcgcat tggtgagctg gcaaaaatgg cggaagtaac acccgacacg attcgttatt
    16201 acgaaaaaca gcagatgatg gagcatgaag tgcgtactga aggtgggttt cgcctgtata
    16261 ccgaaagcga tctccagcga ttgaaattta tccgccatgc cagacaacta ggtttcagtc
    16321 tggagtcgat ccgcgagttg ctgtcgatcc gtatcgatcc tgaacaccat acctgtcagg
    16381 agtcaaaagg cattgtgcag gaaagattgc aggaagtcga agcacggata gccgagttgc
    16441 agagtatgca gcgttccttg caacgcctta acgatgcctg ttgtgggacc gcccatagca
    16501 gtgtttattg ttcgattctt gaagctcttg aacaaggggc gagtggcgtt aagagtggct
    16561 gttgattttt tgcactggca ggattacact cgcgccgtaa aataaccaat tggagttttt
    16621 atgagccgat atcagcatac taaagggcag ataaaggata atgcgataga agcattacta
    16681 catgatccct tattccgaca gcgcgtagag aaaaataaga aggggaaagg cagttacatg
    16741 cgaaaaggaa aacatggcaa tcgggggaac tgggaggcca gtggcaagaa agtaaatcac
    16801 ttttttacca ctggtcttct gctttcaggc gcttgttaag agcggttatt ctgctctttc
    16861 agcaaatcac gaatttctgc cagtaatact tcttctttag ttggtgcagg tgcggcagct
    16921 ggttcttctt ttttccgatt cagtttgttg attagcttaa tcgccataaa gatggcaaag
    16981 gccacaatca gaaaatcaaa gacgttttga atgaagacac cgtaatgcat cacaacagca
    17041 gggatatccc cctgcgcatc gcgtagcgtg acagcaaact gtttaaagtc gatcccgcca
    17101 attaataagc ccagaggtgg catgatgata tcggcaacca gtgaagatac aatcttcccg
    17161 aatgccgcac cgataatgac acccaccgcc aaatccacca cgttcccgcg catcgcaaat
    17221 tcgcgaaatt ctttaataat gctcatgtta ttctccctat gaagccgaca accataagtc
    17281 taacaaatgt taagccattt tcctgccagg aatgaattta attaatcctt gataatcaaa
    17341 gggaaataat aaggcgtcat tagacgcctt attaattaca agaagaaagg gcttggctgg
    17401 aagagtcttt cgacgtcggt aataaacttt ttatctgtga ggaacataat tacgtgatcg
    17461 ccttgctcaa tgcgcagatt gtcattggca atcatcacgt cgtttccacg taccaccgct
    17521 ccaataatcg ttcctggcgg tagcttgatt tcgtcaatga ctctgccgac aacgcgtgag
    17581 gtgctttcat caccgtgagc aacggcttca atagcttctg ctacgccgcg gcgcaatgag
    17641 gaaacaccaa caatatctgc ttttcgcaca tggctaagca acgcagaaat agttgcttgt
    17701 tgtggtgaaa tcgcaatatc gatcacgctc ccctgaacca gatccacata agcgcgacgc
    17761 tggatcaata ccatcacctt tttcgcaccc atacgtttgg caagcatggc ggacatgata
    17821 ttggcctcgt catcgttggt gacggcaata aacagatcaa cttgatcgat atgttcttcg
    17881 gccagcagtt cttgatccga cgcatcacca aaaaagacga tcgtattctg caacttttcc
    17941 gccagttcgg cagcgcgctg ctgattacgt tcgatgagtt taacgctgta atctttttcc
    18001 agacgacgcg ccagccctgc accgatatta ccgccaccaa ccagcatgat ccgcttatac
    18061 ggtttttcca gtcgctgtaa ttcactcatc accgcgcgga tatgctgtga agcggcaata
    18121 aagaacactt catcaccagc ttccacaatg gtcgaacctt gtggacgaat ggggcgatcg
    18181 tggcggaaaa ttgctgccac acgagtatcg atatgtggca tatgttcgcg catggtcgaa
    18241 agtgcgttac caatcagcgg gccgccataa taggctttaa ccacagcgag gctgacttta
    18301 ccctcagcga agttcaccac ctgcaatgcg ccgggatact caatcagtcg gtaaatatta
    18361 tcgataacca actgctctgg tgcgatcaga tgatcaatcg gtacagcatc tgaatgaaat
    18421 agcttatcgg catcgcgcac gtagtctggt gagcggatgc gagcgatgcg attaggggtg
    18481 ttgaaaagtg agtaggctac ctggcaggca accatattgg tttcatctga actggttaca
    18541 gcaaccagca tatcggcgtc gtcggcacct gcctcccgca atacgcgtgg atgagagcca
    18601 tgcccctgca cgactcgcag gtcaaattta tcctgcaagg tccgcagacg ctcaccgttg
    18661 gtatcgacaa cagtgatatc gttgttctcg ccaaccaggt tttccgccag tgtgccgcca
    18721 acctggccgg cacccagaat gataattttc atcagtcgcg acccgttatc tcatcacttt
    18781 ttgattagct tagcgtaaaa gaagccgtcg ccctcttcgg caccaggcag attttgttta
    18841 cccggttgct ctggtgttcc tgtttcgcaa agttcggcat cagcggtacg ttgcaaaaag
    18901 gctttaatct gcaggctatt ctcttccggt aacaccgaac aggtggcata gaccagggtt
    18961 ccaccggatt ttaaatgcgg ccaaatggcg tcgagaattt cagactgcaa ttgcgcgagt
    19021 tccgggatat cgcgatcgcg acgtaaccat ttaatatccg gatggcgacg aatcacaccg
    19081 gttgctgaac aaggcgcatc taataaaatg cgatcaaact gttgctcgcc acaccattgg
    19141 gaagggtagc ggccatcacc ttgtttcacg gtcgctttca taccaaggcg ttttaaattg
    19201 tcgtaaacgc gagagaggcg ctgttcgtca atatcaaccg caacaacctg cgcttctggt
    19261 gccacctcaa ggatatgcgt tgttttaccg ccgggggcgg cacaaagatc cagaatgtgt
    19321 tcaccgtttt gtggcgcaag ccaggtcatg caaccttgtg ctgatgcatc ctgaacggta
    19381 acccatccgt cttcaaaacc aggtagcgca tgaacaggtg caggtgtttc cagccgtaca
    19441 gcatcagggt aatccgcatg cgggaaacct ttcattcctg cttcatccaa caatgcaagc
    19501 cagctgtcgc gggaatgatg cgtacgatta acgcgcagcc acattggcgg acgctggtta
    19561 ttggcttcga cgatggattg ccactgctct ggatacgctt tttgcagacg cttcagcaac
    19621 caggaaggat gcagataacg tgcatcactg gcattaaact cggctaataa ctcttcttgc
    19681 tgacgctgga actggcgtaa tacaccgttt atcaaccctt taagttgcgg acgcttaatt
    19741 gcgatagcgc cttcaaccgt ttcagccagc gcagcatgag gtggaatgcg ggtataaagc
    19801 agttgataca aaccaaccat aatcaggtaa tgcacggtcc gctgtttgcc ggtcatcgga
    19861 cgggccatta acttattaat cagccagtct aactgcgaaa gcgtacgcag tacgccaaag
    19921 cacaactctt gaagaagtgc tttgtcttta tcggaaactt tttgctggag cggtggcaga
    19981 atgttgctta atgattgccc ttgctcgacg acttgttcaa cggcctgggc cgccatgcta
    20041 cgtaaattac gttgtttttt cataagtata aaaacgcccg gcaagaccgg gcttagaaga
    20101 gtggactatc agaccagacg gttgcccgga acaaaccatt cccgacgaga gttcaggagg
    20161 tcttgcgcgc tcatcgcttt cttacccgca ggttgtaacg agagcaggtt caggatgcca
    20221 tcaccagtcg caacctgaat gccttgtttg ttggcttcaa ggatcgttcc tggtgcagcg
    20281 ttggttgccg tatcaatgac cgatgctttc cagactttaa ccggctgtcc ttcaatttcc
    20341 agccagctca ttggccatgg attgaaagcg cgaatgcagc gttcaagctg tgctgccgaa
    20401 agtgaccagt caatacgcgc ttcttcttta ctcaactttt cggcgtaagt gacaagagtt
    20461 tcgtcctgaa cttctggttt cgccgtgccg tctgccagtt gtttcaacgt ggtgataagc
    20521 ccttgtgggc caagctctgc cagcttgtcg tacagcgtac cactggtatc ttctgcagta
    20581 atcgggcagg agagcttata gagcatgtca ccggtgtcta aaccgacatc catttgcata
    20641 atggtcacac cagtttctgc atcacccgcc catagtgagc gttggattgg tgcagcaccg
    20701 cgccagcgtg gcagcagtga accatgaacg ttgatacagc caagacgcgg catctccagc
    20761 actgctttag gcagaattaa gccataggcg acgacgacca taacatcagc ctgcagatcg
    20821 gcgaccagtt gctggttttc ttgtggacgc agggaaacag gttgaaaaac gggcagacct
    20881 ttttcctcag ccagaacttt aaccgggctg ggcatcagtt ttttaccgcg tcctgccggt
    20941 cggtctggct gggtgaacac gccaacgacg ttatgaccag aagacaacag cgcgtcgaga
    21001 tgacgcgctg caaagtcagg tgtacccgca aaaataatac gtagtgattc tgacacgtta
    21061 gttcttatcc ttaagcccgg gctttcagac gatccagttt ttcaactttc tgacgaatac
    21121 gttgttgttt caacggtgac agataatcca taaacagttt gccgaccagg tgatccatct
    21181 catgctgaat acagatggct aacagaccgt ctgcttccaa ttcaaatggt ttaccgtcgc
    21241 ggtccagggc gcgaatttta actttctctg cgcgtggcac taaagcacgt tgttcaggga
    21301 tcgacaggca accttcttca atgcctgttt cgccgctttt ttctaaaagc tccggattga
    21361 ttaacaccag ccgttcgtca cggttttccg aaacatcaat aacaatgata cgttgatgga
    21421 tatcaacctg ggttgccgcc aggccaatac cttcttctgc gtacatcgtc tcgaacatat
    21481 catcgacgat acgctgaatt tctgcattca cttcttctac cggtttagca actttgcgaa
    21541 gccgctcgtc cggaatatgt aacacttgca aaactgacat aaatctccag agatgtgttc
    21601 aggagttaga aagattattt cttctattct agacaaatcc ccctctgatt gacagcatca
    21661 ctgaccaatc gcaaagattg ctaaggctgc ttatggcagg gagataagga tggtcgatac
    21721 agaaatttgg ctgcgtttaa tgagtatcag cagcttgtac ggcgatgata tggtccgtat
    21781 agctcactgg ctggcaaaac agtcgcaaat tgatgcggtt ggattgcagc aaacagggct
    21841 tacattgcgg caggcacaac gctttctttc atttccgcga aagagtatcg aaagctcact
    21901 ttgttggttg gagcaaccca accatcattt aatccctgcg gacagcgaat tttatcctcc
    21961 tcaacttctg gtgacgacag attaccccgg cgcactgttt gttgaaggag aactgcacgc
    22021 gctgcattca tttcagcttg ccgtagtggg gagtcgggcg cattcatggt atggcgagcg
    22081 atggggacgg ttattttgcg aaactctggc gacgcgtgga gtgacaatta cgagtggact
    22141 ggcgcgtgga atcgatggtg tggcgcataa agcggcctta caggtaaatg gcgtcagcat
    22201 tgctgtattg gggaatggac ttaataccat tcatccccgc cgccatgccc gactggctgc
    22261 cagtctgctt gaacatggcg gagctctcgt ctcggaattt cccctcgatg ttccacccct
    22321 tgcttacaat ttcccacgaa gaaatcgcat tatcagtggt ctaagtaaag gtgtactggt
    22381 ggtggaagcg gctttgcgca gtggttcgct ggtgacagca cgttgtgcgc ttgagcaggg
    22441 gcgtgaagtt tttgccttgc caggtccaat agggaatccg ggaagcgaag ggcctcactg
    22501 gttaataaaa caaggtgcga ttcttgtgac ggaaccggaa gaaattctgg aaaacttgca
    22561 atttggattg cactggttgc cagacgcccc tgaaaattca ttttattcac cagatcagca
    22621 agacgtggca ttgccatttc ctgagctcct ggctaacgta ggagatgagg taacacctgt
    22681 tgacgtcgtc gctgaacgtg ccggccaacc tgtgccagag gtagttactc aactactcga
    22741 actggagtta gcaggatgga tcgcagctgt acccggcggc tatgtccgat tgaggagggc
    22801 atgccatgtt cgacgtacta atgtatttgt ttgaaaccta tattcacaca gaagctgagt
    22861 tgcgtgtgga tcaagacaaa cttgaacagg atcttaccga cgcaggattt gatcgagaag
    22921 atatctacaa tgccctgctt tggctggaaa agcttgcgga ttatcaggaa ggactggcag
    22981 aaccgatgca actggcctct gatccactct ccatgcgtat ttatacccct gaggagtgtg
    23041 aaagactgga tgccagctgt cgtggttttc tgcttttcct tgagcaaatt caggtgctta
    23101 accttgaaac ccgtgaaatg gtgatagagc gagtgctcgc gctggatacc gcagagttcg
    23161 acctggaaga cctgaaatgg gtaatcctga tggtgttgtt caatattccg ggctgcgaaa
    23221 atgcgtacca gcaaatggaa gaattactct ttgaagtgaa tgaaggtatg ctgcattaat
    23281 catttcttta attcagcata agttgttatg gcgaaatcag cactgttcac ggtgcgtaat
    23341 aatgagtcct gcccaaagtg cggggctgaa ctggttattc gatccgggaa acacggtccg
    23401 tttcttggat gctcacagta tccggcgtgt gactacgtcc gtcctctgaa atcttcagcg
    23461 gatggacata ttgtcaaagt tctggagggg caggtttgcc ttgcatgtgg cgcaaatctg
    23521 gtattacgcc agggacgctt tggtatgttt attggttgca gtaactaccc tgaatgcgaa
    23581 cataccgaac ttatcgataa accggacgaa acagcaatta catgccccca atgccggacg
    23641 ggccatctgg tccagcgccg ctcccgttat ggcaaaacat ttcactcctg tgatcgctac
    23701 ccggagtgtc aatttgccat taacttcaaa cccatagctg gagaatgccc tgagtgtcat
    23761 tatccactac tcatcgaaaa gaaaaccgcg cagggtgtaa aacacttttg tgccagtaaa
    23821 caatgtggaa agccggtttc ggcggaataa taacgtgaat aataacctgc aaggagacgc
    23881 tatcgcagct gcgatagatg tcctcaatga agaacgtgtc atcgcctatc caacggaagc
    23941 cgttttcggt gtcgggtgcg atcctgatag cgaaacagca gtgatgcgac tgttggagtt
    24001 aaaacagcgt ccggttgata aggggctgat tttaatcgcg gcaaattacg agcagcttaa
    24061 accttatatt gatgacacca tgctgactga tgcgcagcgt gaaaccattt tttcccgctg
    24121 gccaggtcct gtcacctttg tctttcccgc gcctgcgaca acaccgcgct ggttgacggg
    24181 ccgctttgat tcgcttgctg tacgagtcac cgaccatccg ttggtggttg ctttgtgcca
    24241 ggcttatggt aaaccgctgg tttctaccag tgccaacttg agtggattgc caccttgtcg
    24301 aacagtagac gaagttcgcg cacaatttgg cgcggcgttc ccggttgtgc ctggtgaaac
    24361 gggggggcgt ttaaatcctt cagaaatccg cgatgccctg acgggtgaac tgtttcgaca
    24421 ggggtaacat aatggaaacc tatgctgttt ttggtaatcc gatagcccac agcaaatcgc
    24481 cattcattca tcagcaattt gctcagcaac tgaatattga acatccctat gggcgcgtgt
    24541 tggcacccat caatgatttc atcaacacac tgaacgcttt ctttcgtgct ggtggtaaag
    24601 gtgcgaatgt gacggtgcct tttaaagaag aggcttttgc cagagcggat gagcttactg
    24661 aacgggcagc gttggctggt gctgttaata ccctcaagcg gttagaagat ggacgcctgc
    24721 tgggtgacaa taccgatggt ataggtttgt taagcgatct ggaacgtctg tcttttatcc
    24781 gtcctggttt acgtattctg ctcatcggcg ctggtggagc atctcgcggc gtactactgc
    24841 cacttctttc cctggactgt gcggtgacaa tcactaatcg gacggtatcc cgcgcggaag
    24901 agttggctaa attgtttgcg cacactggca gtattcaggc gttgggtatg gacgaactgg
    24961 aaggtcatga gtttgatctc attattaatg caacatccag tggcatcagt ggtgatattc
    25021 cggcgatccc gtcatcgctc attcatccag gcatttattg ctatgacatg ttctatcaga
    25081 aaggaaaaac tccttttctg gcatggtgtg agcagcgagg ctcaaagcgt aatgctgatg
    25141 gtttaggaat gctggtggca caggcggctc atgcctttct tctctggcac ggtgttctgc
    25201 ctgacgtaga accagttata aagcaattgc aggaggaatt gtccgcgtga atcaggccat
    25261 ccagtttccg gacagagaag agtgggacga gaataaaaaa tgtgtatgtt ttcccgctct
    25321 cgtgaatggc atgcaactga catgtgcgat ctctggcgag agtctggcgt atcgttttac
    25381 tggagatacg ccagaacagt ggttagcgag ttttcgtcag catcgctggg atctggaaga
    25441 agaagcggaa aacttaattc aggaacaaag tgaagatgat caaggctggg tctggttacc
    25501 ctgatccaga tattcgtcct tccatttcac gtaattattc gcggaatagc gtaacccagc
    25561 cttctcttca tcacttaacg ggcggatctg tttgacgggg ctaccgagat acagatatcc
    25621 gctctccagc cgtttatttt gtgggaccag actacccgca ccaatcatca catcatcttc
    25681 tactattgcg ccatcaagta aaattgagcc catcccaacc aaaactcgat tgccaatggt
    25741 gcagccgtgg agcatcacct tgtgaccaac agtgacatct tcgccaatgg ttaatgggtt
    25801 gccatctggg ttgtacgagg atttatgagt gacatgcaac atactgccat cctggatatt
    25861 ggtgcgtgct ccgatctgta cataatgtac atctccacga atcacaacga gcggccagat
    25921 ccccacatca tcagccagac gaacgtcacc aatcacgaca ctgctatcgt cgatcattac
    25981 gcgctgaccg atttgtggaa aaagatcgcg gtatgggcgt aaaacatcag acatacttac
    26041 ctcagcaata aatgatttac taatgacttt gggggcatta ttggccttgt gcaagtcttt
    26101 tagtatgcaa aaaagcaccg ttttgtgtgc gattgcagca aaaagggtga aaaaacaaca
    26161 aacagaaaaa aagatcaaaa aaatacttgt gcaaaaaatt gggatcccta taatgcgcct
    26221 ccgttgagac gacaacgtga aacacttcac aggatggtcg gaacaacgaa gag
//
LOCUS       DAPGUL010000058        25760 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.058, whole genome shotgun sequence.
ACCESSION   DAPGUL010000058 DAPGUL010000000
VERSION     DAPGUL010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25760
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.058"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            66..1355
                     /locus_tag="RHX21_002656"
     CDS             66..1355
                     /locus_tag="RHX21_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710093.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate degradation bifunctional
                     isomerase/decarboxylase"
                     /protein_id="HDV1987817.1"
                     /translation="MKGTIFAVALNHRSQLDAWQEAFQQSPYKAPPKTAVWFIKPRNT
                     VIGCGEPIPFPQGEKVLSGATVALIVGKTATKVREEDAAEYIAGYALANDVSLPEESF
                     YRPAIKAKCRDGFCPIGETVALSNVDNLTIYTEINGRPADHWNTADLQRNAAQLLSAL
                     SEFATLNPGDAILLGTPQARVEIQPGDRVRVLAEGFPPLENPVVDEREVTTRKSFPTQ
                     PHPHGTLFALGLNYADHASELEFKPPEEPLVFLKAPNTLTGDNQTSVRPNNIEYMHYE
                     AELVVVIGKQARNVSEADAMDYVAGYTVCNDYAIRDYLENYYRPNLRVKSRDGLTPML
                     STIVPKEAIPDPHNLTLRTFVNGELRQQGTTADLIFSVPFLIAYLSEFMTLNPGDMIA
                     TGTPKGLSDVVPGDEVVVEVEGVGRLVNRIVSEDTAK"
     gene            1352..2818
                     /gene="hpaE"
                     /locus_tag="RHX21_002657"
     CDS             1352..2818
                     /gene="hpaE"
                     /locus_tag="RHX21_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-carboxymethyl-2-hydroxymuconate semialdehyde
                     dehydrogenase"
                     /protein_id="HDV1987818.1"
                     /translation="MKKVNHWINGKNVAGNDYFQTTNPATGEVLADVASGGEAEINQA
                     VAAAKEAFPKWANLPMKERARLMRRLGDLIDQNVPEIAAMETADTGLPIHQTKNVLIP
                     RASHNFEFFAEVCQQMNGKTYPVDDKMLNYTLVQPVGVCALVSPWNVPFMTATWKVAP
                     CLALGNTAVLKMSELSPLTADRLGELALEAGIPAGVLNVVQGYGATAGDALVRHHDVR
                     AVSFTGGTATGRNIMKNAGLKKYSMELGGKSPVLIFEDADIERALDAALFTIFSINGE
                     RCTAGSRIFIQQSIYPEFVKRFAERANRLRVGDPNDPNTQVGALISQQHWEKVSGYIR
                     LGIEEGATLLAGGPDKPSDLPAHLKGGNFLRPTVLADVDNRMRVAQEEIFGPVACLLP
                     FKDEAEGLRLANDVEYGLASYIWTQDVSKVLRLARGIEAGMVFVNTQNVRDLRQPFGG
                     VKASGTGREGGEYSFEVFAEMKNVCISMGDHPIPKWGV"
     gene            2820..3671
                     /gene="hpaD"
                     /locus_tag="RHX21_002658"
     CDS             2820..3671
                     /gene="hpaD"
                     /locus_tag="RHX21_002658"
                     /EC_number="1.13.11.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3,4-dihydroxyphenylacetate 2,3-dioxygenase"
                     /protein_id="HDV1987819.1"
                     /translation="MGKLALAAKITHVPSMYLSELPGKNHGCRQGAIDGHKEISKRCR
                     EMGVDTIIVFDTHWLVNSAYHINCADHFEGVYTSNELPHFIRDMTYNYEGNPELGQLI
                     ADEALKLGVRAKAHNIPSLKLEYGTLVPMRYMNEDKHFKVVSISAFCTVHDFADSRKL
                     GEAILKAIEQYDGTVAVLASGSLSHRFIDDQRAEEGMNSYTREFDRQMDERVVKLWRE
                     GQFKEFCNMLPEYADYCYGEGNMHDTVMLLGMLGWDKYDGKVEFITELFPSSGTGQVN
                     AVFPLPA"
     gene            3681..4061
                     /locus_tag="RHX21_002659"
     CDS             3681..4061
                     /locus_tag="RHX21_002659"
                     /EC_number="5.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-carboxymethyl-2-hydroxymuconate
                     Delta-isomerase"
                     /protein_id="HDV1987820.1"
                     /translation="MPHFIVECTENIRQEARLPELFASVNTALAATGIFPLGGIRSRA
                     HWIDTWQMADGKHDYAFVHMTLKIGSGRSLESRQEVGEMLFDLIKTHFASLMESRYLA
                     LSFEIAELHPTLNFKQNNVHALFK"
     gene            4129..4932
                     /gene="hpaH"
                     /locus_tag="RHX21_002660"
     CDS             4129..4932
                     /gene="hpaH"
                     /locus_tag="RHX21_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710089.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo-hepta-3-ene-1,7-dioic acid hydratase"
                     /protein_id="HDV1987821.1"
                     /translation="MFDKHTHTLIAQRLDQAEKQREQIRAISLDYPEITIEDAYAVQR
                     EWVRLKIAEGRTLKGHKIGLTSKAMQASSQISEPDYGALLDDMFFHDGSDIPTDRFIV
                     PRIEVELAFVLAKPLRGPNCTLFDVYNATDYVIPALELIDARCHNIDPETQRPRKVFD
                     TISDNAANAGVILGGRPIKPDELDLRWISALMYRNGVIEETGVAAGVLNHPANGVAWL
                     ANKLAPYDVQLEAGQIILGGSFTRPVPARKGDTFHVDYGNMGSISCRFV"
     gene            4943..5746
                     /gene="hpaI"
                     /locus_tag="RHX21_002661"
     CDS             4943..5746
                     /gene="hpaI"
                     /locus_tag="RHX21_002661"
                     /EC_number="4.1.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-2-oxoheptanedioate aldolase"
                     /protein_id="HDV1987822.1"
                     /translation="MENSFKAALKAGRPQIGLWLGLSSSYSAELLAGAGFDWLLIDGE
                     HAPNNVQTVLTQLQAIAPYPSQPVIRPSWNDPVQIKQLLDVGTQTLLVPMVQNADEAR
                     EAVRATRYPPAGIRGVGSALARASRWNRIPDYLQKANDQMCVLVQIETREAMKNLPQI
                     LDVEGVDGVFIGPADLSADMGYAGNPQHPEVQAAIEQAIVQIREAGKAPGILIANEQL
                     AKRYLELGALFVAVGVDTTLLARAAEALAARFGNSSSISMAKQNNNSVY"
     gene            5768..7123
                     /gene="hpaX"
                     /locus_tag="RHX21_002662"
     CDS             5768..7123
                     /gene="hpaX"
                     /locus_tag="RHX21_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710087.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate permease"
                     /protein_id="HDV1987823.1"
                     /translation="MTTSTLQYKDNKTVEIEHRVINKLFRRLIIFLFILFVFSFLDRI
                     NIGFAGLTMGKDLGLTSTMFGLAATLFYVTYVMCGIPSNMMLAKIGARRWIAGIMVVW
                     GVASTCTMFATSPETLYLLRMLVGIAEAGFLPGILVYLTWWFPAYHRARANALFMIAM
                     PVTMMLGSILSGYILALDGLWNLKGWQWLFLLEGLPSVILGVVTWFYLNDTPDQATWL
                     DENEKQALKTMILREQESAFAHASVPRSTLREVLTPAIMLYTLAYFCLTNTLSAINIW
                     TPQILQSFNTGSSNIMIGLLAAIPQFCTIFGMIWWSRRSDRLKERKKHTILPYLFAAA
                     GWLLASATDHSLIQLSGIIMASMGSFTAMAIFWTTPDQVISLQSRAVAMAVINAVGNV
                     GSAVSPLLIGILKDATGSFSSGLWFVAGLLVLGALVMTRIPMGSREHSLSSELIAPKP
                     Q"
     gene            7133..8023
                     /gene="hpaA"
                     /locus_tag="RHX21_002663"
     CDS             7133..8023
                     /gene="hpaA"
                     /locus_tag="RHX21_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710086.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate catabolism regulatory
                     protein HpaA"
                     /protein_id="HDV1987824.1"
                     /translation="MSSEAIFEHGYENIDLVREYDARYAGEDVHYETFARLANFFGRD
                     MRPHWHDRYFQLHYLVTGRITLQLDEHFYSVRAPLFVLTPPSVPHTFFTEPDSDGHVL
                     TVRQELIWPLVEKLWPGSGDAAMLQGICLSLEGMEHTLAALNHYWPIISLEFQQNKPG
                     REILLQSLAQSIFTILLREAPPNDISTCSVRGEMCLFQKFNRLIDENYRQHLMVPEYA
                     AMLGMSESRLTELCRRFANQSPKRLIFERVSREARRLLLYSEQSINQIALDLGYKDPA
                     YFARFFNRMMGCSPTQFRGR"
     gene            8050..8988
                     /locus_tag="RHX21_002664"
     CDS             8050..8988
                     /locus_tag="RHX21_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001601398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDV1987825.1"
                     /translation="MKISLRSLFVACLIAPVAFTYASELQEMKIVLLGTKGGPSLLKA
                     DRLPMATALIIGNKTWLIDAGYGASLQLVKNNIPLRQIDNILLTHLHSDHILDYPSVL
                     MNAWASGLQDKNIHVFGPPGTRAMTAASWQVFDRDITLRMEEEGKPDPRKLVTAQDVG
                     EGVVYKDDTVTVTALKVPHSPFPDGEAFAYRFDTQGKRIVFSGDTSYFPPLATFSEGA
                     DILVHEAVHEPSVAKLADSIGNGKTLAKAIASHHTTIEDVGKIANEAKVKKLILSHLV
                     PITVPDETWKQEAQKNYSGPIVVGHENMTITIPFAP"
     gene            9215..10777
                     /gene="hpaB"
                     /locus_tag="RHX21_002665"
     CDS             9215..10777
                     /gene="hpaB"
                     /locus_tag="RHX21_002665"
                     /EC_number="1.14.14.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate 3-monooxygenase,
                     oxygenase component"
                     /protein_id="HDV1987826.1"
                     /translation="MKPEDFRVSTQRPFTGEEYLKSLQDGREIYIYGERVKDVTTHPA
                     FRNAAASVAQLYDALHKPEMQDSLCWNTDTGSGGYTHKFFRVAKSADDLRQQRDAIAE
                     WSRLSYGWMGRTPDYKAAFGCALGANPGFYGQFEQNARNWYTRIQETGLYFNHAIVNP
                     PIDRHLPTDKVKDVYIKLEKEIDAGIIVSGAKVVATNSALTHYNMIGFGSAQVMGENP
                     DFALMFVAPMDADGVKLISRASYEMVAGATGSPYDYPLSSRFDENDAILVMDNVLIPW
                     ENVLIYRDFDRCRRWTMEGGFARMYPLQACVRLAVKLDFITALLKKSLECTGTLEFRG
                     VQADLGEVVAWRNTFWALSDSMCSEATPWVNGAYLPDHAALQTYRVLAPMAYAKIKNI
                     IERNVTSGLIYLPSSARDLNNPQIDQYLAKYVRGSNGMDHVQRIKILKLMWDAIGSEF
                     GGRHELYEINYSGSQDEIRLQCLRQAQSSGNMDKMMAMVDRCLSEYDQNGWTVPHLHN
                     NDDINMLDKLLK"
     gene            10795..11307
                     /locus_tag="RHX21_002666"
     CDS             10795..11307
                     /locus_tag="RHX21_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxyphenylacetate 3-monooxygenase reductase
                     subunit"
                     /protein_id="HDV1987827.1"
                     /translation="MQLDEQRLRFRDAMASLSAAVNIITTEGDAGQCGITATAVCSVT
                     DTPPSLMVCINANSAMNPVFQGNGKLCVNVLNHEQELMARHFAGMTGMAMEERFSLSC
                     WQKGPLAQPVLKGSLASLEGEIRDVQAIGTHLVYLVEIKNIILSAEGHGLIYFKRRFH
                     PVMLEMEAAI"
     gene            11700..13850
                     /gene="btsT"
                     /locus_tag="RHX21_002667"
     CDS             11700..13850
                     /gene="btsT"
                     /locus_tag="RHX21_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313340.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate/proton symporter BtsT"
                     /protein_id="HDV1987828.1"
                     /translation="MDTKKLFKHIPWVILGIIGAFCLAVVALRRGEHVSALWIVVASV
                     SVYLVAYRYYSLYIAQKVMKLDPTRATPAVINNDGLNYVPTNRYVLFGHHFAAIAGAG
                     PLVGPVLAAQMGYLPGTLWLLAGVVLAGAVQDFMVLFISSRRNGASLGEMIKEEMGPV
                     PGTIALFGCFLIMIIILAVLALIVVKALAESPWGVFTVCSTVPIALFMGIYMRFIRPG
                     RVGEVSVIGIVLLVASIYFGGVIAHDPYWGPALTFKDTTITFALIGYAFVSALLPVWL
                     ILAPRDYLATFLKIGVIVGLALGIVVLNPELKMPAMTQYIDGTGPLWKGALFPFLFIT
                     IACGAVSGFHALISSGTTPKLLANETDARFIGYGAMLMESFVAIMALVAASIIEPGLY
                     FAMNTPPAGLGITMPNLHEMGGENAPIIMAQLKDVTAHAAATVSSWGFVISPEQILQT
                     AKDIGEPSVLNRAGGAPTLAVGIAHVFHKVLPMADMGFWYHFGILFEALFILTALDAG
                     TRSGRFMLQDLLGNFIPFLKKTDSLVAGIIGTAGCVGLWGYLLYQGVVDPLGGVKSLW
                     PLFGISNQMLAAVALVLGTVVLIKMKRTQYIWVTVVPAVWLLICTTWALGLKLFSTNP
                     QMEGFFYMASQYKEKIANGTDLTAQQIANMNHIVVNNYTNAGLSILFLIVVYSIIFYG
                     FKTWLAVRNSDKRTDKETPYVPIPEGGVKISSHH"
     gene            13900..14103
                     /locus_tag="RHX21_002668"
     CDS             13900..14103
                     /locus_tag="RHX21_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbdD/YjiX family protein"
                     /protein_id="HDV1987829.1"
                     /translation="MFGNLGQAKKYLGQAAKMLIGIPDYDNYVEHMKTNHPDKPYMSY
                     EEFFRERQNARYGGDGKGGMRCC"
     gene            14114..15070
                     /gene="yjiA"
                     /locus_tag="RHX21_002669"
     CDS             14114..15070
                     /gene="yjiA"
                     /locus_tag="RHX21_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313338.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase"
                     /protein_id="HDV1987830.1"
                     /translation="MNPIAVTLLTGFLGAGKTTLLRHILNEQHGYKIAVIENEFGEVS
                     VDDQLIGDRATQIKTLTNGCICCSRSNELEDALLDLLDNLDKGNIQFDRLVIECTGMA
                     DPGPIIQTFFSHEILCQRYLLDGVIALVDAVHADEQMNQFTIAQSQVGYADRILLTKT
                     DVAGEAEKLRERLARINARAPVYTVTHGDIDLGLLFNTNGFMLEENVVSTKPRFHFIA
                     DKQNDISSIVVELDYPVDISEVSRVMENLLLESADKLLRYKGMLWIDGEPNRLLFQGV
                     QRLYSADWDRPWGDEKPHSTMVFIGIQLPEDEIRAAFAGLRK"
     gene            complement(15104..15406)
                     /locus_tag="RHX21_002670"
     CDS             complement(15104..15406)
                     /locus_tag="RHX21_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004020443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnA antitoxin family protein"
                     /protein_id="HDV1987831.1"
                     /translation="MSMVKHKRGTPSTLDVQHEAELKALANKFDEDIDYSDIPPSSDE
                     QWSNAERGKFYRPLKTQASVRIDADVMEWLKRPGKGYQTRLNAILREAMLRDQNKK"
     gene            complement(15545..16279)
                     /locus_tag="RHX21_002671"
     CDS             complement(15545..16279)
                     /locus_tag="RHX21_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000208603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein Fic"
                     /protein_id="HDV1987832.1"
                     /translation="MTTKLLDLSWNANAIPAMQIVGTRAALFTFKTHMAGFVWDAAQL
                     ENNPYTFVEVKTLLDGVTVGGHKVSDTEQVLNLADSAKKLIELVQSGRFDLDKKTFTL
                     LNGIIARNEALEWGVFRGEGDELHYNARVHLGELGTHFPPATEAGAPELNRIFAAGVA
                     QIKEMPPFEGALAMFLFGAYFQFFFDGNKRTSRHMMNGWLMRHGYNPISVPAARALEF
                     NSKMVRFYHSKDASEMMAFLVDCYQV"
     gene            complement(16323..18422)
                     /locus_tag="RHX21_002672"
     CDS             complement(16323..18422)
                     /locus_tag="RHX21_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HDV1987833.1"
                     /translation="MKATEARLLDFLKRSQQFVIPIYQRTYSWSEEQCRQLWDDVIRA
                     GQRDDVPAHFIGSVVYIEQGLYQVSGISPLLVIDGQQRLTTAMLLLEALSRHLGDDEV
                     MDGFSAMKLRNYYLLNPYESGERGFKLLLTQTDRASLLALIRQKPLAENCSLRVKENF
                     EFFHEQIGKLHGNFTALCQGLSKLLIVDVALNRGQDNPQLIFESMNSTGKALSQADLV
                     RNYVLMGLEPEHQSQLYDDYWRPMELAFGQKGYTDYFDSFMRNYLTVKTGEIPRIGDV
                     YEAFKRYARKPGVIDSGMEALVADIRTFADYFCAMALDSEKDKTLKMAFQDLRELKVD
                     AAWPFLLVLYHDYKQGILSAADFLGATRLIESYIFRRAVCAIPTNSFTKTFATFYKVL
                     DKERYLESIAAHLLDLPSYRRFPDDDEFQRELKTRDLYNFRNRSYWLRRFENHDRKER
                     VYVDTYTIEHIMPQNPNLSVKWRDDLGPEWKRIHKKWLHTLGNLTLTGYNSSYSDRPF
                     AKKRDIKGGFKESPLRLNTGLGQCEIWDRAAIQKRAERLSELAIDVWAIPKLSEDVLA
                     RYRTVVERGTGYVLADFPQLEEGTHIRVLFDSLSYAVMTLDAGVTREILKLYVAFKAE
                     TNFVDVVPQKSRLRLSLNMPFHELVDPKCMAKDVTDIGRWGNGDVEIGFSDLSELPYV
                     MGLIRQAFKKQMDNAMV"
     gene            18707..21052
                     /locus_tag="RHX21_002673"
     CDS             18707..21052
                     /locus_tag="RHX21_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HDV1987834.1"
                     /translation="MSSTNFSQIAAFLWSVADLLRGDFKQSQYGRIILPFTLLRRLEC
                     VLETSKDAVIAEAQKVKAMKLPEEAQEKMILRATNGLTFFNASAMDLSKMGQNGIQDN
                     LENYIQSFSSDAREIFEHFKFSEFVGQLADANLLFKVVQIFAKADLYPEHVTNHDMGL
                     VFEELIRRFAESSNETAGEHFTPRDIVNLTTSLVFFDDDDALNKDGIIRTIYDPTAGT
                     GGFLSSGMEYVHKQNPNAVMRAFGQELNPESYAICKADMLIKGQDVSLIKLGNTLSND
                     QLPAEKFDYMLSNPPFGVDWKKIETDINNEHKLKGADGRFGPGLPRVSDGSLLFLLHL
                     ISKMRDAKSGGGRIGIILNGSPLFTGGAGSGESEIRRYILEADLLEGIIALPTDMFYN
                     TGIATYVWVLSNKKAPERKGKVQLIDGSNLCGKMRKSLGSKRNILGEEDIGLITRTFG
                     DFEPVATTTLAALGLEKAPEQKSSRGRQPATTKTEAAKTFASKVFHSTEFGYRRITVE
                     RPLRLSAQISDDAIATLRFAPKPFNAPMAQLYDAFAFQWQDGNYGDLTAVESEARAIL
                     KADFSELKEKQIKDLLDSKLWLAQRGLMEKARRIQAAMRMLAGGKETVSNDFNQFQLT
                     LKEALRTAGVKLDAKENKQFIDAITRKNPDAEPVISKVLKEAPQPLYGAFEYHGKVVE
                     FESDGDLRDNENVPLNPAVSTNELIEDYFKAEVLPHVADAWINADKRDAKDGDIGIVG
                     YEIPFNRHFYVYTPPRPLEEIDADLDAVSAEIMKLLQEVHS"
     gene            21052..22455
                     /locus_tag="RHX21_002674"
     CDS             21052..22455
                     /locus_tag="RHX21_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HDV1987835.1"
                     /translation="MAGLNKYQAYPEYRDSGMEWCNELPLNWKKTKLRWLSNIFAGGT
                     PSKNVIDYWENGTVPWISSGAVNQGYIVEPSTYISNAALENSSAKWIPKGALVVALAG
                     QGKTKGMVAQLGINTTCNQSMAAIVLYKKNQSRYIFWWLISNYQNIRNMAGGDLRDGL
                     NLELLGDIQCPKPRNDESSKIALFLDHETAKIDDLIEKQQQLIELLKEKRQAVISHAV
                     TKGLNPDVPMKDSGLTGLGEAPSHWFKSKLANTGDETKGCFVNGPFGSDLLASELKEE
                     GVPVVYIRDIKATGYNRKSTVYVTHQKAQQLEICKLSSNDVIFSKVGDPPGEACVYPK
                     NEPDAVITQDVMRVRVNKKTFNAHFIAYLLNSNFGRQTINNISIEGTRKRVSLGDFKT
                     TKFIFPPLGEAQSIVNALNEKCAQIDLIIFKTNQAIMLIQERRTALISAAVTGKIDLR
                     NWTAPIPEAETPTEVSA"
     gene            22452..25715
                     /locus_tag="RHX21_002675"
     CDS             22452..25715
                     /locus_tag="RHX21_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HDV1987836.1"
                     /translation="MSNDIAKEVNLQKDIIAQMLEKGWIVGKSDGYDRERAIYAQDTL
                     NFVQTTQPQEWEKLARVYPNDTERHFLDALVAQLKKADSNATDIQSRTWGTLGVLRHG
                     LKIRNARFSLCQFKPEHNLNPETLARYQQNICRIVPELVYSLYASNSVFAETGVKAKK
                     WRIDLVLFINGLPIATLELKSEFKQAVQNAIAQYKKTRLPKDPATNKPEPLLTFKRGA
                     LVHFAVSQYDVFMTTKLAGDSTFFLPFNKGTKDGGAGNEIPEDTHRYATDYLWNEVLL
                     PDNLLKILASFVHLHIEEKEEWNGLKAKKESLIFPRYHQWDVVNKLLEAATVEGTGYK
                     YLIQHSAGSGKSNSIAWTAHQLSRLYDVKGEKQFHSVIVVTDRTVLDDQLQDTIWQFE
                     HADGVVGRINNKEGDGSKSEKLANALENSQPIIIVTIQTFPFVLKAIENSVSLKQRKY
                     AVIADEAHSSQSGSTARQLKEVLMSEEMDNDVVLSSEDILDATIAARKGSSNLNYYAF
                     TATPKSKTLELFGRRPRPDEPASKTNKPEAFHVYSMRQAIEEGFILDVLKNYTNYKVA
                     YQLLQKLEDKDREVDSKRAKIKLNQWVTLHDHNISQKVKVIVEHFRKHVMHLLGGQAK
                     AMVVTSSRKAAVRYKLAFDKYISENNYQKISAMVAFSGEVEFQEGDHNSLALLNQKFT
                     EINMNPGLKGRDMRKAFDSDDYQVMLVANKFQTGFDQPKLCAMYVDKALGGVECVQTL
                     SRLNRTYPGKAESGTFVLDFYNDPDEILGAFQPYFQTAELTDVSDPQQVFDLFEKLRA
                     TQIFQWHEVEQFCEAFFIKNKSNAAISNICKPAVERWKKRYLMAIDAYLTAKEMFERT
                     KKTGDTVLITNAENSFKACKQEKDRLEIFKKDLGSFVRFYEFMSQIVEYDDKDLEKLS
                     LFARHLRPLLHEQRLEEDEVDLSNVEMSHYRLSKIHEQDLRLQEETPDYTLDASNDIG
                     TAKAKDKKEEFLSQVLSQMNELFISDHLTDKDMISNAFSVYNKITENENVMTQIKNNP
                     PEQAILGDFLQAVDNAVMDSNDARQEFMLQYLSDPVRAKGFAYLMFDMLTGKIALPT"
BASE COUNT         6600 a         6609 c         6539 g         6012 t
ORIGIN      
        1 caatcgggaa taaaagtaat cattaacata ttaatgatta aaatgatcga atccgaggag
       61 tggtaatgaa aggcactatc ttcgccgtag cgttgaacca tcgcagccaa cttgatgcat
      121 ggcaggaagc gttccagcaa tccccctaca aagccccgcc taaaactgcg gtctggttta
      181 ttaaaccgcg caatacggtg attggttgcg gtgaaccgat tccctttcca cagggtgaaa
      241 aggtactgag cggtgcgact gttgcgctga ttgtgggaaa aacggcgacg aaagtacgtg
      301 aagaagatgc ggcagagtac atcgccggat atgcgctggc taacgacgtc agcctgccgg
      361 aagagagctt ttaccgcccg gcaatcaaag caaaatgtcg tgatggattc tgccccattg
      421 gcgaaaccgt ggctctcagc aatgtcgata atctgaccat ctataccgag atcaacgggc
      481 gtcctgccga tcactggaat accgccgatt tacaacgtaa cgccgcgcag ttgctgagcg
      541 ccctgagcga atttgccacg ctgaatccag gcgacgccat tctgctcggc acgccacagg
      601 cgcgcgtgga aatacagcca ggcgatcgcg ttcgtgttct cgcagaaggt ttcccgccgc
      661 tggaaaatcc ggtagtggac gaacgtgaag tgaccacgcg caagagcttc ccaacgcagc
      721 cacacccgca cggcacgctg tttgccctcg gcctgaacta cgccgaccac gccagcgaac
      781 tggaatttaa gccaccggaa gaaccgctgg tgttcctgaa agcgccaaat accctcactg
      841 gcgataacca gacctccgtg cgtccaaaca atattgaata catgcactat gaagcggagc
      901 tggtggtagt tattggcaaa caggcgcgta acgtcagcga agccgatgcc atggattatg
      961 tcgcgggcta caccgtgtgt aacgactacg ccattcgcga ctatctggaa aactactacc
     1021 gccctaacct gcgggtcaaa agccgcgacg gactgacgcc gatgctttca accatcgtgc
     1081 cgaaagaggc gatcccggac ccgcataatc tgacccttcg caccttcgtc aacggcgagt
     1141 tacgccagca aggcaccacc gccgatctga tcttcagcgt gcccttcctg atcgcctact
     1201 taagcgaatt tatgaccctg aatccgggcg acatgatcgc caccggcaca ccaaaaggct
     1261 tatctgacgt ggtgcctggc gatgaagtag tggtggaagt agaaggcgtg ggccgcctgg
     1321 tgaaccgaat tgtgagtgag gatacagcga aatgaaaaaa gtaaatcatt ggatcaacgg
     1381 caaaaatgtc gcaggtaacg actacttcca gaccaccaat ccggcaacgg gtgaagtgct
     1441 ggcggatgtg gcctctggcg gtgaagcgga gatcaatcag gcggtagcgg cagcgaaaga
     1501 ggcgttcccg aaatgggcca atctgccgat gaaagagcgt gcgcgcctga tgcgccgtct
     1561 gggcgatctg atcgaccaga acgtgcctga gatcgccgcg atggaaaccg ccgacacggg
     1621 cctgccaatc catcagacca aaaatgtgtt gatcccacgc gcttcccaca actttgaatt
     1681 tttcgcggaa gtctgccagc agatgaacgg caagacttat ccggtcgacg acaagatgct
     1741 caactacacg ctggtgcagc cggtaggcgt ttgtgcactg gtgtcaccgt ggaacgtgcc
     1801 gtttatgacc gccacctgga aggtcgcgcc gtgtctggcg ctgggcaata ccgcggtact
     1861 gaaaatgtcg gaactctccc cgctgaccgc cgaccgcctg ggtgagctgg cgctggaagc
     1921 cggtattccg gcaggcgtgc tgaacgtggt acagggctac ggcgcaaccg caggggatgc
     1981 gctggttcgt catcatgacg tacgtgccgt gtcgttcacc ggcggtacgg ccaccgggcg
     2041 caacatcatg aaaaacgccg ggctgaaaaa atactccatg gaactgggcg gtaaatcgcc
     2101 ggtgctgatt tttgaagatg ccgatattga acgcgcgctg gacgccgccc tgttcaccat
     2161 cttctcgatc aacggcgaac gctgcaccgc cggttcgcgc atctttattc agcaaagcat
     2221 ctacccggaa ttcgttaaac gctttgccga acgcgccaac cgtctgcgcg tgggcgatcc
     2281 gaacgatccg aatacccagg ttggcgcgct tattagccag cagcactggg aaaaagtctc
     2341 cggctatatc cgtctcggca ttgaagaagg cgcaaccctg ctggcgggcg gcccggataa
     2401 accgtccgac ctgcctgcgc acctgaaagg cggcaacttc ctgcgcccaa ccgtgctggc
     2461 agacgttgat aaccgtatgc gagtcgccca ggaagagatt ttcgggccgg tcgcctgcct
     2521 gctgccgttt aaagacgaag ccgaaggctt acgtctggca aacgacgtgg agtacggcct
     2581 cgcgtcgtac atctggacac aggatgtcag caaagtgtta cgcctggcgc gtggcattga
     2641 agctggcatg gtgttcgtca acacccagaa cgtgcgtgac ctgcgccagc catttggcgg
     2701 cgtaaaagcc tccggcaccg ggcgtgaagg cggtgagtac agcttcgaag tgttcgcgga
     2761 aatgaagaac gtctgcattt ccatgggcga ccatccaatt ccgaaatggg gagtctgata
     2821 tgggtaagtt agcgttagcc gccaagatca cgcacgtacc gtcgatgtat ctctctgaac
     2881 tgccagggaa aaaccacggt tgccgccagg gcgcgatcga cgggcataaa gagatcagca
     2941 agcgttgccg ggaaatgggc gtcgatacca ttatcgtttt cgatacccac tggctggtca
     3001 acagtgctta tcacatcaac tgtgcagacc attttgaagg cgtctacacc agtaacgagc
     3061 tgccgcattt tattcgtgac atgacctaca actacgaggg caacccggag ttggggcagc
     3121 ttattgccga tgaagcctta aagctcggcg tgcgggcaaa agcgcacaat attcccagcc
     3181 tgaaactgga atacggcacg ctggtgccga tgcgctacat gaatgaagac aagcacttca
     3241 aagtggtctc catctccgca ttctgtaccg ttcatgattt tgccgacagc cgcaagctgg
     3301 gcgaagcgat tctgaaagcg atcgaacagt acgacggcac cgtggcggtc cttgccagcg
     3361 gttcgttatc gcaccgcttt attgacgatc agcgtgcgga agaagggatg aacagctaca
     3421 cccgcgagtt cgaccgccag atggacgagc gcgtggtgaa gttgtggcgc gaaggccagt
     3481 tcaaagagtt ctgcaatatg ctgccggagt acgctgacta ctgctacggc gaaggcaata
     3541 tgcacgacac ggtgatgctg ctggggatgc tcggctggga taaatacgac ggcaaggtag
     3601 agtttatcac cgagctgttc ccaagctctg gcaccggtca ggttaacgct gttttcccgc
     3661 ttcccgcgta aggaaccacc atgccgcact ttatcgtgga atgtactgaa aatattcgtc
     3721 aagaagcccg cttacctgag ctgtttgcca gtgttaacac tgcactggcg gcgacgggga
     3781 tttttccgct tgggggaata cgtagccggg cgcactggat cgatacctgg caaatggctg
     3841 atggcaagca cgattacgcc tttgtgcata tgacgctaaa aatcggcagc gggcgcagtc
     3901 tggaaagccg tcaggaagta ggcgaaatgc tgtttgatct gattaaaacg cacttcgcct
     3961 cactgatgga gagccgttac ctggcgcttt catttgagat tgcagagctg cacccgacgt
     4021 tgaatttcaa acagaacaac gtacacgcgt tgtttaaata aatttgtacc agcttccagg
     4081 ccggatgata aggcgcagcc gcatccggca atgccacagg atatcgccat gttcgataaa
     4141 cacacccaca ccctgatcgc ccagcgtctg gatcaggcag aaaaacagcg cgaacagatc
     4201 cgcgcgatct cgctggatta cccggagatc accatcgaag acgcttacgc ggtgcagcgc
     4261 gaatgggtcc gcctgaaaat tgccgaaggc cgtacgctga aaggccacaa aatcggcctg
     4321 acctcgaaag cgatgcaggc cagctcgcaa atcagcgaac cggattacgg tgccctgctg
     4381 gatgacatgt tcttccacga tggcagcgat atcccgaccg atcgctttat cgtgccgcgc
     4441 attgaagtgg agctggcttt cgtgctggca aaaccgctgc gtggaccaaa ctgcacgctg
     4501 ttcgacgtct acaacgccac ggattatgtg atcccggcgc tggagctgat cgacgctcgc
     4561 tgccacaaca tcgatccgga aacccagcgc ccgcgcaaag tgttcgacac catttccgat
     4621 aacgccgcca acgccggggt gatcctcggc ggtcgtccca ttaagcccga tgagttggat
     4681 ctgcgctgga tctccgccct gatgtatcgc aatggcgtga ttgaagaaac cggcgtcgcc
     4741 gctggtgtgc tgaatcatcc ggcaaacggc gtagcctggc tggcgaacaa actcgcaccg
     4801 tatgacgtac aactggaagc cgggcaaatc attctcggcg gttcgttcac ccgcccggtt
     4861 ccggcgcgta agggcgacac cttccacgtc gattacggca acatgggctc cattagctgc
     4921 cgctttgttt aaggagagaa cgatggaaaa cagttttaaa gcggcgctga aagcaggccg
     4981 cccgcagatc ggattatggc tggggctgag tagcagctac agcgcagagt tactggccgg
     5041 agcaggattc gactggttat tgatcgacgg tgagcacgcg ccgaataacg tgcaaaccgt
     5101 gctcacccag ctacaggcga ttgcgcccta ccccagccag ccggtgatac gcccatcgtg
     5161 gaacgatccg gtgcaaatca aacaactgct ggacgtcggc acacaaacct tactggtgcc
     5221 gatggtacaa aacgccgacg aagcccgtga agcggtacgc gccacccgtt atccccccgc
     5281 cggtattcgc ggtgtgggca gtgcgctggc acgcgcctcg cgctggaacc gtattccgga
     5341 ttacctgcaa aaagccaacg atcaaatgtg cgtactggtg cagatcgaaa cgcgtgaggc
     5401 aatgaagaac ttaccgcaga ttctggacgt ggaaggcgtc gacggcgtgt ttatcggccc
     5461 ggcggatctg agcgccgata tgggttatgc cggtaatccg caacacccgg aagtgcaggc
     5521 cgcgattgag caggcgatcg tgcagatccg cgaagcgggt aaggcgccgg gtatcctgat
     5581 cgccaatgag caactggcaa aacgctacct ggaactgggc gcgctatttg tcgccgtcgg
     5641 cgttgacacc accctgctcg cccgcgccgc cgaagcgctg gcagcacggt ttggtaatag
     5701 ttcttctatt tcgatggcga agcaaaacaa caactctgtc tactaaacgt acgatgtgga
     5761 gcgcatcatg acgacctcta ccctgcaata taaagataat aaaactgttg aaattgaaca
     5821 tcgtgtcatt aataaattat ttcgtcgcct aatcattttt ctttttattc tgtttgtttt
     5881 ttcgtttctt gatcgcatca atataggatt tgccggactg acaatgggca aggatcttgg
     5941 cctgacgtcc acaatgtttg gcctcgccgc gacactcttt tatgtcacgt acgtcatgtg
     6001 cgggatcccc agtaatatga tgttagcgaa aattggcgct cgtcgatgga tcgctgggat
     6061 catggtggtc tggggagttg cttccacctg cacaatgttt gcaacaagcc ccgaaacact
     6121 ctatctactg cgtatgctgg ttggtattgc tgaggcgggt tttttacctg gtattttggt
     6181 ttatctgacc tggtggttcc cggcatatca tcgggccaga gccaatgcct tatttatgat
     6241 agcgatgcca gtcactatga tgctgggatc gatcctttca ggctacattc tggccttgga
     6301 tggactgtgg aatctaaaag gctggcaatg gctctttttg ctggaaggtc tgccatcggt
     6361 cattcttggt gtcgtcacct ggttttatct caacgataca ccagaccagg cgacctggct
     6421 tgatgaaaac gaaaaacagg ctttaaaaac gatgattctc cgtgaacaag agagtgcatt
     6481 tgcccatgca tctgttccac gctcaacctt acgtgaagtc ctgaccccag ccatcatgct
     6541 atatacactt gcttattttt gcctgaccaa tactctgagt gcgattaata tctggacgcc
     6601 gcaaatccta cagagtttca atactggcag tagcaacatc atgattggtt tgctggcggc
     6661 catcccccaa ttctgcacaa tttttggcat gatctggtgg agtcgtcgtt ccgaccgtct
     6721 taaagaacgc aaaaagcata cgattcttcc ctacctgttt gccgctgccg gatggttact
     6781 cgcttctgcg actgatcaca gcctcattca actgagcggc atcattatgg cctcaatggg
     6841 atcatttacc gcaatggcta tcttttggac gacaccggat caagtaataa gcttgcaatc
     6901 gcgtgccgtt gcgatggctg tcatcaatgc tgtcggtaat gtaggttcag cagtcagtcc
     6961 attacttatc ggtattttga aagatgcaac cggcagtttt agctcaggtt tgtggtttgt
     7021 agcaggatta ctggtactgg gcgcgttagt catgacccga attcctatgg ggagtcggga
     7081 acactctctt tcatctgaac ttatcgcacc aaaaccgcaa taaggagtca tgatgtccag
     7141 tgaagctatc tttgaacatg gttatgaaaa tattgatttg gtccgggaat atgatgcccg
     7201 ctacgctggt gaagatgtgc attatgaaac atttgccagg ttagcgaatt tctttggacg
     7261 cgatatgcgc cctcactggc acgatagata ttttcaactc cattatctgg tcactggacg
     7321 cattacttta cagctggatg agcacttcta ttctgtgcgc gcaccgcttt ttgtactaac
     7381 accaccatcg gtgccacata ctttctttac tgagcctgat agcgacgggc atgttctgac
     7441 cgtacgtcag gagttaattt ggcccctggt agaaaagctc tggcctggta gtggagatgc
     7501 cgcaatgcta caaggtatct gtctgtcgct ggagggaatg gaacatacac tggcggcatt
     7561 aaatcattat tggccgataa tatccctgga gtttcaacaa aataagccag gacgggaaat
     7621 tctattgcaa tcactggcgc aaagtatttt tacaatccta ctgcgtgaag caccaccaaa
     7681 tgatatttca acatgcagcg tgcgcggcga gatgtgttta ttccagaagt ttaatcggct
     7741 gattgacgaa aattatcgcc aacatttaat ggtccctgaa tatgcagcaa tgctcggtat
     7801 gagtgaatca cggcttaccg agctatgccg acgttttgcc aatcaatcgc cgaagagatt
     7861 gattttcgaa cgagtgagcc gggaagccag acggcttctg ctctatagcg agcaaagcat
     7921 caaccagatt gcccttgatc ttggctacaa agatcccgcc tatttcgccc gttttttcaa
     7981 ccgaatgatg ggttgctcac caacacaatt ccgtggtcgc tgaccattta tcaacctgag
     8041 agactcgaca tgaaaatatc tttacgctca ctatttgtgg cgtgcctgat tgcgccagtg
     8101 gcattcacct acgcctccga actgcaagaa atgaaaattg tactacttgg aacgaaaggt
     8161 ggcccttctt tattaaaagc tgaccgtttg ccgatggcaa cggcacttat tattggcaat
     8221 aaaacatggt taattgatgc tggttacggg gccagcttac aactggtaaa aaataatatt
     8281 ccactgcgcc agattgataa tattttactc acccatttac acagtgatca tattctggac
     8341 tatccctcag tcttaatgaa tgcatgggct agcggtctgc aggacaaaaa tattcatgtg
     8401 ttcggtccgc caggtacccg agccatgacc gctgccagtt ggcaggtctt cgatcgggac
     8461 atcacactgc gtatggaaga agaaggaaaa cccgatcctc gcaagctcgt tacagctcaa
     8521 gatgttggtg aaggcgtagt ttataaagat gataccgtga ccgtgactgc attaaaggtt
     8581 cctcattctc ctttccctga cggtgaggct tttgcttatc gcttcgacac acaaggcaag
     8641 cgaattgtct tctcaggaga tacctcgtac tttcccccac tggcaacttt ctcagaaggc
     8701 gctgatatac ttgtgcatga ggccgtacat gagccctccg tcgctaagct ggcagacagt
     8761 attggcaatg gtaaaacact ggcaaaagcc attgcttctc accatacgac tattgaggat
     8821 gtaggcaaaa ttgccaatga agcaaaagtg aaaaaactca tccttagcca cctggtacca
     8881 atcaccgttc cggatgaaac atggaagcaa gaagcacaga aaaactattc aggccctatc
     8941 gtcgttggtc atgaaaatat gacgattacc attccattcg ccccataaac aattccgtcc
     9001 ccgttagccc ttgttagcgg ggaatattat gatttgcctt actgtaagtt gatcacgatc
     9061 gcagtttact atttaactcc accttgctgg cgaaaagtac caacgttcgc ctgaaacgtc
     9121 tcttcccgac aaccgcgttc aacgattcaa ttgaataaca aaaacaacac acaaaattaa
     9181 caatcgtatt ccgattaata ctgtagaggt cgacatgaaa ccagaagatt tccgcgtcag
     9241 tacccaacgt ccgttcaccg gggaagagta tctgaaaagc ctgcaggatg gtcgcgagat
     9301 ctatatctat ggcgagcgag tgaaagacgt caccactcat ccggcatttc gtaatgcggc
     9361 agcgtctgtt gcccaactgt acgacgcgct gcacaaaccg gagatgcagg actctctgtg
     9421 ttggaacacc gacaccggca gcggcggcta tacccataaa ttcttccgcg tggcgaaaag
     9481 tgccgacgac ctgcgccagc aacgcgacgc catcgctgag tggtcacgcc tgagctatgg
     9541 ctggatgggc cgtaccccag actacaaggc tgctttcggt tgcgcactgg gcgcgaatcc
     9601 gggcttttac ggtcagttcg agcagaacgc ccgtaactgg tacacccgta ttcaggaaac
     9661 tggcctctac tttaaccacg cgattgttaa cccaccgatt gatcgtcatt tgccgaccga
     9721 taaagtgaaa gacgtttaca tcaagctgga aaaagagatt gacgccggga ttatcgtcag
     9781 cggtgcgaaa gtggttgcca ccaactcggc gctgactcac tacaacatga ttggcttcgg
     9841 ctcggcacaa gtgatgggcg aaaacccgga cttcgcactg atgttcgttg cgccaatgga
     9901 tgccgatggc gtgaaattaa tctcccgcgc ctcttatgag atggtcgcgg gtgctaccgg
     9961 ctcgccgtac gactacccgc tctccagccg cttcgatgag aacgatgcga ttctggtgat
    10021 ggataacgtg ctgatcccat gggaaaacgt gctgatctac cgcgattttg atcgctgccg
    10081 tcgctggacg atggaaggcg gtttcgcccg tatgtatccg ctgcaagcct gtgtgcgcct
    10141 ggcagtgaaa ctcgacttca tcacggcact gctgaaaaaa tctctcgaat gtaccggcac
    10201 cctggagttc cgtggtgtgc aggccgatct cggtgaagtg gtggcgtggc gcaacacctt
    10261 ctgggcattg agtgactcga tgtgttcaga agcgacacca tgggtcaacg gtgcttattt
    10321 accggatcat gccgcactgc aaacctatcg cgtactggca ccaatggcct acgcgaagat
    10381 caaaaacatt atcgaacgca acgttaccag tggcctgatc tatctccctt ccagtgcccg
    10441 tgacctgaat aatccgcaga tcgaccagta tctggcgaag tatgtgcgcg gttcgaatgg
    10501 tatggatcac gtccagcgca tcaagatcct caaactgatg tgggacgcca ttggcagcga
    10561 gtttggtggt cgtcacgaac tgtatgaaat caactactcc ggtagccagg atgagattcg
    10621 cctgcagtgt ctgcgccagg cacaaagctc cggcaatatg gacaagatga tggcgatggt
    10681 tgatcgctgc ctgtcggaat acgaccagaa cggctggact gtgcctcacc tgcacaacaa
    10741 cgacgatatc aacatgctgg ataagctgct gaaataacgc agcaggaggt taagatgcaa
    10801 ttagatgaac aacgcctgcg ctttcgtgac gcaatggcca gcctgtcggc agcggtaaat
    10861 attatcacca ccgagggcga cgccggacaa tgcgggatta cggcaacggc tgtctgctcg
    10921 gtcacggata caccaccgtc gctgatggtg tgcattaacg ccaacagtgc gatgaacccg
    10981 gtttttcagg gcaacggcaa gttgtgcgtc aacgtcctca accatgagca ggaactgatg
    11041 gcacgccact tcgcgggcat gacaggcatg gcgatggaag agcgttttag cctctcatgc
    11101 tggcaaaaag gtccgctggc gcagccggtg ctaaaaggtt cgctggccag tcttgaaggt
    11161 gagatccgcg atgtgcaggc aattggcaca catctggtgt atctggtgga gattaaaaac
    11221 atcatcctca gtgcagaagg tcacggactt atctacttta aacgccgttt ccatccggtg
    11281 atgctggaaa tggaagctgc gatttaagct ccagcccctt cacgcattcg tcgaaggggc
    11341 atttttattg tgatctcaat cacatatcca cccgatgaat aattcttgcc caaccgctca
    11401 ccgccattcc tgaccgctta cgtccctaaa ataaccactc agttatttac cttactttac
    11461 gcgcgcgtaa ctctggcaac atcactgcag gatagcggtc aatttacctc ctcaaacgca
    11521 acgcaaacct agaacggctt cggcctatga ttaacaaatt actctatgaa ttttggtttg
    11581 caggaaggca gcaagtgagt gaatccccgg gagcttacaa cagtaagtga caggggtgaa
    11641 cgaacgcagc tgccgcacct gtaagccaaa agacgacgag taaaatgcca ggttttacta
    11701 tggatacgaa aaaactattc aagcacatac cctgggtgat tctcggaatc atcggtgcat
    11761 tctgcctcgc ggtagttgca ttacgtcggg gggagcacgt cagtgccctg tggatcgtgg
    11821 tcgcctctgt gtcggtgtat ctggtggctt atcgctacta cagtctgtac atcgcccaga
    11881 aggtaatgaa actcgacccc acgcgagcga cgcctgcggt tattaacaac gacggtctga
    11941 actatgttcc gaccaaccgt tacgtgttgt ttggtcacca cttcgccgct atcgccggtg
    12001 ctggtccgct ggtgggtccg gttctcgccg cgcagatggg ctacctgcct ggcacgctgt
    12061 ggctgctggc gggggtagtg ctggccggtg cggtacagga ctttatggtg ctgtttatct
    12121 cctctcgccg taacggcgca tctctcggtg agatgatcaa agaagagatg ggaccagtac
    12181 cggggactat cgcgctgttt ggctgtttct taatcatgat catcatcctc gccgtcctgg
    12241 cgctgattgt ggttaaagcc ctggccgaaa gtccgtgggg tgtcttcacc gtttgctcaa
    12301 ccgtaccgat tgcgctgttt atgggtatct acatgcgctt tatccgtccg gggcgtgtgg
    12361 gtgaagtttc tgtcattggt atcgtgctgc tggttgcctc tatctacttc ggtggcgtga
    12421 ttgctcacga tccgtactgg ggtccggcac tgacctttaa agacaccacc attaccttcg
    12481 cgctgattgg ctatgcgttt gtttccgcac tgctgccggt gtggctgatc cttgcaccgc
    12541 gcgactatct ggcaaccttc ctgaaaatcg gtgttatcgt cggcctggcg ctgggtatcg
    12601 tggtgctgaa cccggaactg aaaatgcctg cgatgaccca gtacattgac ggtactggcc
    12661 cgctgtggaa aggcgctctg ttcccgttcc tgttcatcac catcgcctgt ggtgcggtat
    12721 ctggcttcca cgcactgatc tcttccggta cgacgccgaa actgctggct aacgaaaccg
    12781 acgcgcgttt cattggctac ggcgcaatgc tgatggagtc cttcgtggcg attatggcgc
    12841 tggttgcagc gtccatcatc gaaccgggtc tttacttcgc gatgaacacc ccgcctgctg
    12901 gccttggcat caccatgcct aacctgcatg aaatgggtgg cgagaacgcg ccgatcatca
    12961 tggcgcagct gaaagacgtt accgcacacg cggcagcgac cgtcagctcc tggggcttcg
    13021 tgatttcgcc agagcagatc ctgcaaaccg cgaaagacat tggtgagcct tctgtcctga
    13081 accgtgcagg tggtgcgccg acgctggcgg taggtatcgc gcacgtgttc cacaaagtac
    13141 tgccgatggc tgacatgggc ttctggtatc acttcggtat tctgttcgaa gccctgttca
    13201 tcctgaccgc gctggatgcg ggtacccgtt ctggccgctt tatgctgcaa gacctgctgg
    13261 gtaacttcat cccgttcctg aaaaaaaccg actctctggt tgctggtatc atcggtactg
    13321 cgggctgtgt gggtctgtgg ggctacctgc tgtatcaggg cgtggtcgat ccgctgggcg
    13381 gcgttaagag cctgtggccg ctgttcggta tctccaacca gatgctggcc gccgtggcgc
    13441 tggtactggg taccgttgtg ctgattaaga tgaagcgcac ccaatacatc tgggtaactg
    13501 ttgttccggc tgtatggctg cttatctgca ccacctgggc gctgggcctg aaactgttca
    13561 gtaccaaccc gcagatggaa ggcttcttct acatggcaag ccagtacaaa gagaagattg
    13621 ctaacggtac tgacctgacg gcgcagcaga ttgccaacat gaaccacatc gttgtgaata
    13681 actacaccaa cgcaggtctg agtattctgt tcctgatcgt ggtgtacagc atcatcttct
    13741 atggtttcaa aacctggctt gcggtgcgta acagcgacaa acgtactgac aaagaaacac
    13801 cgtacgttcc aatcccggaa ggcggcgtga agatctcttc gcaccactaa ccgtgtttag
    13861 ccccgcttcg gcggggcttt gttcttatca gagtgaacta tgtttggtaa cttaggacag
    13921 gcaaaaaaat atctcggcca ggcggcgaag atgttgattg gcattccaga ctacgacaac
    13981 tacgtcgagc atatgaagac caaccatccc gacaagccgt acatgagcta tgaagaattc
    14041 ttccgcgaac gccagaacgc gcgctacggc ggcgatggta aaggcggtat gcgctgttgt
    14101 taatggagag agcatgaacc cgattgcagt gaccctactc accggttttt taggcgcggg
    14161 caaaactacc ctgctgcgcc atattcttaa cgaacaacac ggctacaaga ttgccgtgat
    14221 tgaaaacgaa ttcggcgaag tctccgttga tgatcaactg attggcgacc gcgccacgca
    14281 gatcaaaacg ctgaccaacg gctgcatctg ctgttcgcgc tccaacgagc tggaggacgc
    14341 gctactcgac ctgctggaca atctcgacaa gggcaatatt cagttcgacc gtctggtcat
    14401 tgaatgcacc ggcatggccg atcctggccc gattattcag acctttttct cccatgagat
    14461 tttatgccag cgctacctgc tggacggcgt gattgcgctg gtggatgcgg tacatgccga
    14521 tgagcagatg aaccagttca ccatcgccca gtcccaggtt ggctacgccg accgtattct
    14581 gctgactaaa accgacgtcg caggcgaagc agagaaactg cgtgaacgtc tggcacgcat
    14641 caacgcccgc gcgccggtct acaccgtcac ccacggcgac atcgacctgg gcctgttgtt
    14701 caacaccaac ggttttatgc tggaagaaaa cgtcgtcagc accaaaccgc gtttccactt
    14761 tatcgcggat aaacaaaacg atatttcgtc gattgtggtg gaactggatt acccggtaga
    14821 tatcagcgaa gtttcccgcg tgatggaaaa cctgctgctg gaatcggcag ataaactgct
    14881 gcgttacaaa gggatgctgt ggattgacgg cgaacctaac cgcctgctgt tccagggcgt
    14941 ccagcgcctc tacagcgccg actgggacag gccgtggggc gatgaaaaac cgcatagcac
    15001 gatggtgttt atcgggattc agctgccgga ggatgagatt cgggcggcgt ttgcggggtt
    15061 gaggaagtaa ttttggatga tggccgccat gtggcggcct gaattatttt ttgttctgat
    15121 cgcgcagcat cgcttcacgt aaaattgcgt tcaggcgagt ttgatagcct ttaccaggtc
    15181 gcttcagcca ttccatcaca tcagcatcaa tacgcaccga agcctgggtt ttcaatggcc
    15241 gataaaactt accgcgttct gcgttagacc attgctcatc gctggaaggc gggatatcac
    15301 tgtaatcaat atcttcgtcg aatttattcg ccagtgcctt cagttcggcc tcatgctgca
    15361 catcgagtgt agagggggtc cctcgtttat gtttaaccat gctcatagcg actcctctct
    15421 ttacgatctg cttttcgtgc actgatgatt cgaatgttgg aaatagcatc acgttttagg
    15481 aaaagatagg gaagttgata tgaaggggct ggatggcagc attgggacac catccagcac
    15541 ttattcaaac ctgatagcaa tccaccaaaa atgccatcat ttcactggca tctttgctgt
    15601 gataaaagcg caccattttg ctgttgaact ccagcgcacg agctgcgggt acactaatgg
    15661 gattgtaacc gtggcgcatt aaccagccgt tcatcatatg gcgactggta cgcttgttgc
    15721 catcaaagaa aaactgaaaa taagcaccaa ataaaaacat tgccagcgcc ccttcgaacg
    15781 gtggcatctc ttttatttgt gccacacctg cggcgaatat tcgattcagt tcaggtgcac
    15841 ctgcttctgt ggctggtggg aaatgggtgc ccaactcgcc gaggtgaacg cgcgcattgt
    15901 aatgtaactc atcaccttcg ccgcgaaaaa cgccccactc cagcgcctca ttacgcgcaa
    15961 taatgccgtt aagcaacgtg aacgttttct tatcaagatc gaaacgcccg gattgcacaa
    16021 gttcaatcag tttttttgcg ctatctgcca ggttcaacac ctgctcagta tcactgacct
    16081 tatgcccgcc aacggtgacg ccatcgagca gcgttttaac ttcaacaaag gtataggggt
    16141 tattttccag ttgcgcggca tcccagacaa accctgccat atgcgttttg aaggtaaaca
    16201 aggccgcgcg cgtaccgaca atttgcatcg ccgggatggc atttgcattc cagctcaggt
    16261 ccagtagttt ggttgtcatt agaggatcct tgattgcatg gtaaagagga tattattcca
    16321 tattaaacca tcgcgttatc catctgcttt ttaaatgcct gacgaattaa tcccatcaca
    16381 taaggaagct cagaaagatc gctgaaacct atttcaacat cgccattgcc ccaacggcct
    16441 atatctgtga catctttagc catacatttt gggtcaacca gttcatggaa tggcatattt
    16501 agtgataaac gtaagcgact tttttgcggc accacatcaa caaaattcgt ctccgctttg
    16561 aaggcaacat agagcttcaa tatttctcgc gtaaccccag cgtccagcgt cataacggca
    16621 taagaaaggc tgtcaaaaag tacgcggatg tgcgtacctt cttcaagttg cgggaaatca
    16681 gcaaggacat atcccgttcc tcgttcaacg acagtgcgat aacgagccaa cacgtcttcc
    16741 gaaagtttgg ggatcgccca gacgtctatt gccagctcgg acagacgttc cgctctcttt
    16801 tgtatcgctg cacgatccca tatttcacat tgccctaacc ccgtgttcag gcgtaatgga
    16861 ctttccttaa agccaccttt tatatctcgt ttcttcgcaa atggacggtc gctgtagctt
    16921 gagttatagc cagttaacgt taaattaccc aacgtatgga gccatttttt atggatacgc
    16981 ttccattccg gaccaaggtc atcgcgccac ttcaccgata aattagggtt ctgcggcatg
    17041 atatgttcaa tcgtataagt gtcaacatag acccgttctt tacgatcgtg gttttcaaat
    17101 ctgcgtagcc aatagctgcg attacggaag ttgtagagat cgcgagtttt cagttcacgt
    17161 tgaaattcat catcatccgg gaaacgacgg taggaaggca gatccagcaa atgcgccgca
    17221 atgctctcca gataacgctc tttatccagc actttgtaaa acgtagcgaa ggttttagta
    17281 aatgagttgg tgggaatggc acagactgcg cgccggaaga tatacgactc aattaaacgc
    17341 gtggcaccta aaaaatccgc ggcagaaagg atcccctgtt tatagtcgtg ataaagcacc
    17401 aacaggaacg gccatgcagc atcaactttc agttcccgca gatcctgaaa cgccatcttt
    17461 aaggttttat ccttttcgct atccagcgcc atcgcacaaa aatagtcagc aaacgtacga
    17521 atatccgcaa ccagcgcctc catcccgcta tctattacgc caggttttcg cgcatagcgt
    17581 ttaaaggctt catagacatc accaattcgc ggaatctcac ctgtttttac cgtaaggtaa
    17641 ttacgcataa aactgtcgaa atagtcagtg tatcccttct gaccaaacgc cagctccatg
    17701 ggccgccagt aatcgtcgta cagttggctt tgatgttctg gctccagccc catcagaaca
    17761 tagttgcgta ctagatccgc ctgactcagc gcttttcctg ttgagttcat gctttcgaag
    17821 attagttgcg gattatcctg accgcgattc aaggcgacat ccacaatcag cagtttggaa
    17881 aggccctgac ataacgcggt gaaattgccg tggagtttgc ctatttgctc atggaaaaac
    17941 tcaaaattct ctttcacgcg tagagagcaa ttttctgcca gcggtttttg tctaatcaat
    18001 gccagcaggc tcgctctgtc cgtttgcgta agaagtaact taaaaccacg ctcgcccgat
    18061 tcatacggat tgagcagata atagtttcgt aatttcatgg cggagaaacc atccatcacc
    18121 tcgtcatcac caagatgtct ggacaacgct tccagcaata acatcgccgt tgtcaggcgt
    18181 tgctgaccgt caatcaccag taatggcgag atccccgaaa cctgatatag gccctgttcg
    18241 atatacacca ccgagccgat gaaatgcgcc gggacatcat cacgctgccc ggcacgtatt
    18301 acatcgtccc agagctggcg gcactgttcc tctgaccatg aataagtacg ctgataaatg
    18361 ggaataacga attgctgaga gcgttttaga aaatcgagta atcgggcttc ggtggctttc
    18421 atgaatgact cctgtcaaat tgcgctggca aacggcgtca ttatgctgcg aataaaaaat
    18481 aaaagttagc gtctttgttt ctgcaaaaat accattccag gataaatcaa aatatattaa
    18541 gaaacacctc aaaacgcatt cattagaaca attaatactt ccaaccaata tttataacgc
    18601 attgaaaatg atcatgtttt tgatcatcac aacgatagtt tgatataaca aagcattcac
    18661 ttcacattga atatccccct ctttttcagg gcaaggaatg ctttttatgt catcaactaa
    18721 tttcagccag attgcagcct tcctgtggtc tgtcgccgac ctgttacgcg gcgattttaa
    18781 acaatcacaa tatggacgaa ttattctccc tttcactctt cttcgtcgtc tggaatgtgt
    18841 actcgaaaca agtaaagacg cggtcattgc cgaggcacaa aaagtaaaag ccatgaaact
    18901 gccagaggaa gcccaggaga aaatgatcct gcgggcgact aatggcctca cgttctttaa
    18961 tgcctcagcg atggatctca gcaaaatggg gcaaaatggc atacaggaca acctggaaaa
    19021 ctacatccag tcgttctctt cggatgcccg cgaaattttc gaacacttca agttcagcga
    19081 gtttgtcgga cagctggcgg atgcaaactt actgttcaaa gtggtgcaaa tattcgctaa
    19141 agcagattta tacccggagc acgtcaccaa ccacgatatg gggctggtat ttgaggagct
    19201 gatccgacgt tttgccgaga gttctaacga aaccgccggg gagcacttta ccccgcgtga
    19261 tatcgtcaat ctgaccacct cgctggtgtt tttcgatgat gatgatgcgc tcaataaaga
    19321 cggcatcatc cgcaccattt acgatccaac ggcaggaacc ggcggctttc tctcctccgg
    19381 catggagtac gtccataaac aaaaccccaa tgccgtgatg cgcgcgtttg gtcaggagtt
    19441 aaatccggaa tcctacgcca tctgtaaagc cgatatgctg attaagggcc aggacgtcag
    19501 ccttattaaa ctcggcaaca ccctttccaa cgatcaactc cccgcagaaa aattcgatta
    19561 catgctttct aatccacctt tcggcgtgga ctggaaaaag atagaaaccg acatcaacaa
    19621 cgagcacaaa ctcaaaggtg ctgatggtcg ctttggcccc ggcctgcccc gagtctccga
    19681 cggttcgttg ctgtttctgc tgcatctgat cagcaaaatg cgcgatgcca aaagcggtgg
    19741 cggacggatc ggcatcattc ttaatggttc gccgttattc accggcggcg caggcagcgg
    19801 tgaaagcgag atccgccgct acattctgga agcggatttg ctggaaggca ttatcgccct
    19861 gcccaccgat atgttttaca acaccggtat cgctacctat gtttgggtgc tgtctaacaa
    19921 aaaagcgcca gaacgcaaag gtaaagtcca gctaatcgac ggcagcaacc tgtgcggaaa
    19981 gatgcgtaaa tcgctgggat caaaacgtaa tattctcggg gaggaggata ttggtttaat
    20041 cacccgcacg tttggcgatt tcgaacccgt tgccaccact acgcttgcgg cgttaggcct
    20101 ggagaaagca cccgaacaaa aatccagccg gggacgccag cccgcaacaa ccaaaaccga
    20161 ggcggcaaaa acctttgcca gcaaagtctt tcacagcacc gagtttggct atcgtcgcat
    20221 caccgttgag cgcccgttac gcctgtcggc tcagataagt gatgacgcca ttgccacatt
    20281 gcgctttgcg ccgaagccgt ttaacgcgcc gatggcgcaa ctgtatgacg cctttgcttt
    20341 ccagtggcag gacggtaatt acggcgactt aacagcggta gaaagtgaag cccgcgccat
    20401 tcttaaagcc gattttagcg agctgaaaga gaagcaaatt aaagatctgc tcgacagcaa
    20461 attatggctg gcccagcgcg ggttaatgga aaaagcgcgg cgtattcagg cagcgatgag
    20521 gatgctggcg ggtggcaaag agactgttag caatgacttt aatcagttcc agttgacgct
    20581 gaaagaggcg ctcagaaccg caggcgtgaa gctggatgcg aaagagaaca agcagtttat
    20641 cgatgctatc acccgcaaaa acccggacgc cgagccggta atcagcaagg ttctgaaaga
    20701 agcgccccaa ccgctgtacg gcgcgtttga gtaccacgga aaggttgtgg agtttgaatc
    20761 ggatggcgac ctgcgtgata acgagaatgt gccgttaaat ccggcggtat ctaccaacga
    20821 gttgatcgag gattacttca aagcggaagt attgccgcat gttgcggatg cgtggatcaa
    20881 tgccgataaa cgcgatgcga aagatgggga tatcgggatt gtggggtatg aaattccgtt
    20941 taatcgtcat ttttatgttt atacaccgcc gcgaccgttg gaggagattg atgctgattt
    21001 ggatgcggta agcgctgaga ttatgaaact gttgcaggag gtacattcct gatggcgggg
    21061 ttaaataaat atcaggcgta tccggagtat agggattctg ggatggagtg gtgtaatgaa
    21121 ttaccactaa actggaaaaa aactaagctg aggtggctat ccaatatttt tgcaggagga
    21181 actccctcca aaaatgttat tgattattgg gagaatggta cagttccctg gattagttct
    21241 ggagcagtaa atcaaggtta tatagtcgag ccatccacat atatatctaa cgctgcactt
    21301 gaaaatagta gtgccaagtg gataccaaaa ggggcacttg ttgtcgcttt agctgggcag
    21361 ggaaaaacca aaggtatggt tgcacaactt ggtattaata ccacttgtaa ccaatccatg
    21421 gcggccattg tattgtataa aaagaatcaa tctcgctata tattttggtg gctcatttct
    21481 aattatcaga atatacgtaa catggctggc ggtgatttac gagacggttt aaaccttgaa
    21541 cttttaggcg atatacaatg cccaaaacct cgtaatgatg aatcttctaa gattgcactt
    21601 ttccttgatc atgaaacagc aaaaatcgat gacctgatcg agaaacaaca acaactcatt
    21661 gaactactaa aagaaaaacg tcaggcagtg attagccatg cggtgaccaa agggctaaat
    21721 cctgatgtgc cgatgaaaga ttctggttta acaggattag gcgaagcacc ctcccactgg
    21781 tttaagagta aattagccaa tactggtgat gaaactaaag gatgcttcgt aaatgggcca
    21841 tttggaagtg atttactagc aagtgaattg aaagaagaag gggtacctgt cgtatacatt
    21901 cgagatataa aagcgacagg ttataacaga aaaagtactg tatatgttac tcatcaaaaa
    21961 gcccaacagc ttgaaatatg taaattatcc tcaaatgatg tgattttttc aaaagtcgga
    22021 gatcccccag gagaagcgtg cgtttatcct aaaaatgaac cagatgctgt cataacgcaa
    22081 gatgttatga gagtaagagt taataaaaaa accttcaatg cacatttcat agcatatcta
    22141 ttgaactcaa attttgggcg acaaaccatt aataacatta gtattgaggg aacaagaaaa
    22201 agagtttcat taggtgactt taaaacaacc aagtttatat ttcccccatt gggtgaagca
    22261 caatcaatcg tcaacgcctt gaatgaaaaa tgcgcacaaa ttgatctcat aatatttaaa
    22321 accaatcaag caataatgct aatccaggaa cgccgcaccg cccttatctc cgccgccgtc
    22381 accggcaaaa tcgacctacg caactggacc gcccccatcc ccgaagcgga aacacccacg
    22441 gaggtcagcg catgagcaac gacatcgcca aagaggtcaa cttacaaaaa gacatcatcg
    22501 ctcagatgtt ggaaaaaggc tggattgtcg gcaaaagtga cggctacgac cgggaacgag
    22561 caatatacgc acaggatacc ttaaacttcg ttcagaccac ccaaccgcag gagtgggaga
    22621 aactcgcccg cgtctacccc aacgacaccg agcgccattt cctcgacgcg ctggttgcgc
    22681 agttaaaaaa agccgacagc aacgccaccg acatccagtc gcgcacctgg ggtacgctcg
    22741 gcgtacttcg ccacggactg aaaatccgca atgcccgttt ttcgctgtgt cagtttaaac
    22801 cggaacataa tctcaacccg gaaacgctgg cgcgctatca gcagaatatc tgccgtatcg
    22861 tgccggaact ggtctacagc ctgtatgcct caaatagcgt ctttgcagaa acgggcgtga
    22921 aagccaaaaa atggcgcatc gacctggtgc tgtttatcaa cggcctgcca attgccacgc
    22981 tggagctgaa atccgaattc aaacaggcgg tgcagaacgc cattgcgcag tacaaaaaga
    23041 cccgcctgcc gaaagatccc gccaccaata aaccggaacc gctgctgacc tttaagcgcg
    23101 gcgcgctggt gcattttgcc gtcagccagt atgacgtctt tatgaccacc aaactcgcgg
    23161 gtgacagcac cttcttcctg ccgtttaaca aaggcaccaa agacggcggc gcaggcaacg
    23221 agatccccga agatacccac cgctacgcca cagattatct gtggaatgaa gtgctgctgc
    23281 cggacaactt attaaaaatc ctcgccagtt ttgtccattt gcatattgaa gaaaaagagg
    23341 agtggaacgg gctgaaagcg aagaaagaga gcctgatttt cccgcgttat catcagtggg
    23401 atgtggtcaa caaactgctg gaggccgcga cggtcgaagg caccggctat aaatacctga
    23461 tccagcacag cgcaggttcc ggaaagtcga actctattgc ctggaccgcc caccagcttt
    23521 ctcgtctgta cgacgtgaaa ggggaaaaac agttccactc cgttatcgtg gtgacggacc
    23581 gcacggtgct ggacgaccag cttcaggaca ccatctggca gttcgaacac gccgacggcg
    23641 tggtcgggcg catcaataac aaagagggcg atggctctaa atcggaaaag ctggccaacg
    23701 cgctggaaaa ctcgcagcca attattatcg tcaccatcca gacgttcccg ttcgtgctga
    23761 aagctatcga aaacagcgtt agcctgaagc agcgtaaata cgcggttatc gccgatgaag
    23821 cgcactcctc gcagagcggt tccaccgccc gtcagcttaa agaagtgctg atgagcgaag
    23881 aaatggataa tgacgtggtg ctgtcgtcag aagatattct ggatgcgacc attgccgccc
    23941 ggaaaggcag cagtaacctg aactactacg cctttaccgc cacgccaaaa tccaaaaccc
    24001 tcgaactttt tggtcgccgt ccacgtcccg atgaaccggc gtcaaaaacc aataaacctg
    24061 aggccttcca cgtctactcc atgcgccagg caatcgaaga aggctttatc ctcgacgtgc
    24121 tgaaaaacta caccaactac aaagtggcgt atcagttgct gcaaaagctg gaagacaaag
    24181 accgcgaagt cgatagcaaa cgggcgaaga ttaagctcaa ccagtgggtg acactgcacg
    24241 accacaatat ctcgcagaag gtgaaggtga ttgtggagca cttccgcaaa catgtgatgc
    24301 acctgcttgg cggccaggct aaagcgatgg tggtcaccag ttcacgcaaa gccgctgtac
    24361 gctacaagct ggcgtttgat aaatacatta gcgagaacaa ttaccagaaa atcagcgcga
    24421 tggtggcgtt ttccggggaa gttgaattcc aggaaggcga ccataacagc ctggcattgt
    24481 taaaccagaa atttactgaa ataaacatga accccggcct gaaagggcgg gatatgcgca
    24541 aagccttcga cagcgatgat tatcaggtca tgttggtcgc caataaattc cagaccggtt
    24601 ttgaccagcc gaaactgtgc gcgatgtacg tggataaagc cctcggcggc gtcgagtgcg
    24661 tgcagacgct ctcccgcctg aatcgcacct atccgggcaa agcggaatca ggcacttttg
    24721 ttctcgattt ttataacgat ccggacgaga tcctcggcgc attccagccc tatttccaga
    24781 cggcggaact gaccgatgtc agcgatccgc agcaggtttt cgatctgttt gaaaaactgc
    24841 gcgccacgca gatctttcag tggcatgaag tcgagcagtt ctgcgaggca ttcttcatca
    24901 aaaataaatc gaatgcagcg atcagtaata tatgcaaacc ggcggtagaa cgctggaaaa
    24961 agcgttatct gatggcgata gacgcttatc tgaccgccaa agagatgttc gagcgcacca
    25021 aaaaaacggg cgatacggtg ttaatcacta atgcggaaaa cagttttaaa gcctgtaagc
    25081 aggagaaaga tcgcctggaa atattcaaaa aggatctcgg cagctttgtt cgcttttatg
    25141 aatttatgtc gcagatcgtc gagtacgatg acaaagatct ggaaaaactg agcctgtttg
    25201 cccgccattt gcgtccgctg ctgcatgaac aacgtctgga agaggatgag gttgatctca
    25261 gtaacgtgga gatgagtcac tatcgcttat cgaaaatcca tgaacaagat ttacgcttac
    25321 aggaagaaac gcctgactat acgctggatg caagtaatga tattggtacg gcaaaagcga
    25381 aagataaaaa agaggagttt ttatcgcagg tgctttctca gatgaatgaa ttattcatta
    25441 gcgaccattt gaccgacaaa gatatgatca gcaatgcttt ttcggtgtat aacaaaataa
    25501 ctgaaaatga aaatgttatg acacaaatta aaaataatcc gccagaacaa gctattcttg
    25561 gtgatttcct ccaggcagtt gataatgctg taatggacag taatgacgct cgacaagaat
    25621 ttatgttgca atatttatca gatccagttc gggcaaaggg ctttgcttat ctgatgtttg
    25681 atatgctaac ggggaaaatt gctttgccaa cataaaaata cgttgatagc cggggtcgca
    25741 ctttctaccc cggccatatt
//
LOCUS       DAPGUL010000059        25734 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.059, whole genome shotgun sequence.
ACCESSION   DAPGUL010000059 DAPGUL010000000
VERSION     DAPGUL010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25734
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.059"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            299..718
                     /locus_tag="RHX21_002676"
     CDS             299..718
                     /locus_tag="RHX21_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit"
                     /protein_id="HDV1987837.1"
                     /translation="MLFIKPADLREIVTFPLFSDLVQCGFPSPAADYVEQRIDLNQLL
                     IQHPSATYFVKASGDSMIDGGISDGDLLIVDSAITASHGDIVIAAVDGEFTVKKLQLR
                     PTVQLIPMNSAYSPITISSEDTLDVFGVVIHVVKAMR"
     gene            718..1986
                     /gene="umuC"
                     /locus_tag="RHX21_002677"
     CDS             718..1986
                     /gene="umuC"
                     /locus_tag="RHX21_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase V catalytic protein"
                     /protein_id="HDV1987838.1"
                     /translation="MFALCDVNAFYASCETVFRPDLWGKPVVVLSNNDGCVIARNAEA
                     KALGVKMGDPWFKQKDLFRRCGVVCFSSNYELYADMSNRVMSTLEELSPRVEIYSIDE
                     AFCDLTGVRNCRDLTDFGREIRATVLQRTHLTVGVGIAQTKTLAKLANHAAKKWQRQT
                     GGVVDLSNLERQRKLMSALPVDDVWGIGRRISKKLDAMGIKTVLDLADTDIRFIRKHF
                     NVVLERTVRELRGEPCLQLEEFAPTKQEIICSRSFGERITDYPSMRQAICSYAARAAE
                     KLRSEHQYCRFISTFIKTSPFALNEPYYGNSASVKLLTPTQDSRDIINAATRSLDAIW
                     QAGHRYQKAGVMLGDFFSQGVAQLNLFDDNAPRPGSEQLMTVMDTLNAKEGRGTLYFA
                     GQGIQQQWQMKRAMLSPRYTTRSSDLLRVK"
     gene            complement(2032..2562)
                     /gene="dsbB"
                     /locus_tag="RHX21_002678"
     CDS             complement(2032..2562)
                     /gene="dsbB"
                     /locus_tag="RHX21_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="disulfide bond formation protein DsbB"
                     /protein_id="HDV1987839.1"
                     /translation="MLRFLNQCSQGRGAWLLMAFTALALELTALWFQHVMLLKPCVLC
                     IYERCALFGVLGAALIGAIAPKTPLRYVAMVIWLYSAFRGVQLTYEHTMLQLYPSPFA
                     TCDFMVRFPEWLPLDKWVPQVFVASGDCAERQWDFLGLEMPQWLLGIFIAYLIVAVLV
                     VISQPFKAKKRDLFGR"
     gene            complement(2708..4249)
                     /gene="nhaB"
                     /locus_tag="RHX21_002679"
     CDS             complement(2708..4249)
                     /gene="nhaB"
                     /locus_tag="RHX21_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na(+)/H(+) antiporter NhaB"
                     /protein_id="HDV1987840.1"
                     /translation="MEISWGRALWRNFLGQSPDWYKLALIIFLIVNPLIFLISPFVAG
                     WLLVAEFIFTLAMALKCYPLLPGGLLAIEAVFIGMTSAEHVREEVAANLEVLLLLMFM
                     VAGIYFMKQLLLFIFTRLLLSIRSKMLLSLSFCVAAAFLSAFLDALTVVAVVISVAVG
                     FYGIYHRVASSRTEDTDLQDDSHIDKHYKVVLEQFRGFLRSLMMHAGVGTALGGVMTM
                     VGEPQNLIIAKAAGWHFGDFFLRMSPVTVPVLICGLLTCLLVEKLRWFGYGETLPEKV
                     REVLQQFDDQSRHQRTRQDKIRLIVQAIIGVWLVTALALHLAEVGLIGLSVIILATSL
                     TGVTDEHAIGKAFTESLPFTALLTVFFSVVAVIIDQQLFSPIIQFVLQASEHAQLSLF
                     YIFNGLLSSISDNVFVGTIYINEAKAAMESGAITLKQYELLAVAINTGTNLPSVATPN
                     GQAAFLFLLTSALAPLIRLSYGRMVWMALPYTLVLTLVGLLCVEFTLAPVTEWFMQMG
                     WIATL"
     gene            4471..5190
                     /gene="fadR"
                     /locus_tag="RHX21_002680"
     CDS             4471..5190
                     /gene="fadR"
                     /locus_tag="RHX21_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid metabolism transcriptional regulator
                     FadR"
                     /protein_id="HDV1987841.1"
                     /translation="MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVT
                     RTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLL
                     SVRTNISTIFIRTAFRQHPDKAQEVLATANEVADHADAFAELDYNIFRGLAFASGNPI
                     YGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSALCSEGAHDQVYETVRRYGHE
                     SGEIWHRMQKNLPGDLAIQGR"
     gene            complement(5242..6774)
                     /locus_tag="RHX21_002681"
     CDS             complement(5242..6774)
                     /locus_tag="RHX21_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoVR family protein"
                     /protein_id="HDV1987842.1"
                     /translation="MATIDSMNKDTTRLSDGPDWTFDLLDVYLAEIDRVAKLYRLDTY
                     PHQIEVITSEQMMDAYSSVGMPINYPHWSFGKKFIETERLYKHGQQGLAYEIVINSNP
                     CIAYLMEENTITMQALVMAHACYGHNSFFKNNYLFRSWTDASSIVDYLIFARKYITEC
                     EERYGVDEVERLLDSCHALMNYGVDRYKRPQKISLQEEKARQKSREEYLQSQVNMLWR
                     TLPKREEEKTVAEARRYPSEPQENLLYFMEKNAPLLESWQREILRIVRKVSQYFYPQK
                     QTQVMNEGWATFWHYTILNHLYDEGKVTERFMLEFLHSHTNVVFQPPYNSPWYSGINP
                     YALGFAMFQDIKRICQSPTEEDKYWFPDIAGSDWLETLHFAMRDFKDESFISQFLSPK
                     VMRDFRFFTVLDDDRHNYLEISAIHNEEGYREIRNRLSSQYNLSNLEPNIQIWNVDLR
                     GDRSLTLRYIPHNRAPLDRGRKEVLKHVHRLWGFDVMLEQQNEDGSIELLERCPPRMG
                     NL"
     gene            7104..8402
                     /gene="dadA"
                     /locus_tag="RHX21_002682"
     CDS             7104..8402
                     /gene="dadA"
                     /locus_tag="RHX21_002682"
                     /EC_number="1.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-amino acid dehydrogenase"
                     /protein_id="HDV1987843.1"
                     /translation="MRVVILGSGVVGVASAWYLNQAGHEVTVIDREPGAALETSAANA
                     GQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTQFQLKWMWQMLRNCDTSHYM
                     ENKGRMVRLAEYSRDCLKALRAETNIQYEGRQGGTLQLFRTEQQYENATRDIAVLEDA
                     GVPYQLLESSRLAEVEPALAEVAHKLTGGLQLPNDETGDCQLFTQNLARMAEQAGVKF
                     RFNTPVDQLLCDGEQIYGVKCGDEVIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYS
                     LTIPIAQEDGAPVSTILDETYKIAITRFDNRIRVGGMAEIVGFNTELLQPRRETLEMV
                     VRDLYPRGGHVEQATFWTGLRPMTPDGTPVVGRTRFKNLWLNTGHGTLGWTMACGSGQ
                     LLSDLLSGRTPAIPYEDLSVARYSRGFTPSRPGHLHGAHS"
     gene            8412..9482
                     /gene="dadX"
                     /locus_tag="RHX21_002683"
     CDS             8412..9482
                     /gene="dadX"
                     /locus_tag="RHX21_002683"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309712.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolic alanine racemase DadX"
                     /protein_id="HDV1987844.1"
                     /translation="MTRPIQASLDLQALKQNLSIVRQAAPHARVWSVVKANAYGHGIE
                     RIWSALGATDGFALLNLEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHS
                     NWQLKALQNARLKAPLDIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHF
                     AEAEHPDGISSAMARIEQAAEGLECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPS
                     GQWRDIANTGLRPVMTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGY
                     PRHAPTGTPVLVDGVRTMTVGTVSMDMLAVDLTPCPQAGIGTPVELWGKEIKIDDVAA
                     AAGTVGYELMCALALRVPVVTV"
     gene            complement(9868..11604)
                     /locus_tag="RHX21_002684"
     CDS             complement(9868..11604)
                     /locus_tag="RHX21_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309713.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HDV1987845.1"
                     /translation="MDATTIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGML
                     AGVDGVGGIPFDNYPFAYMVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLI
                     TSGLTGMMAAWLFNLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
                     NDPMAVFLTITLIAMIQQHESSVSWMFVVDILQQFGLGIVIGLGGDYLLLQMINRIAL
                     PAGLYPLLALSGGILIFALTTALEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAW
                     LAQIAMFLVLGLLVNPSDLLPIAIPALILSAWMIFFARPLSVFAGLLPFRGFNLRERV
                     FISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKV
                     VVPPVGRPVSRVGLDIHPENPWEQFVYQLSADKWCVGAALRDLHMPKETRIAALFRDN
                     QLLHPTGSTRLREGDVLCVIGRERDLPALGKLFSQSPPVALDQRFFGDFILEASAKYA
                     DVALIYGLEDGREYRDKQQTLGEIVQQLLGAAPVVGDQVEFAGMIWTVAEKEDNEVLK
                     IGVRVAEEEAES"
     gene            complement(11699..12613)
                     /gene="ldcA"
                     /locus_tag="RHX21_002685"
     CDS             complement(11699..12613)
                     /gene="ldcA"
                     /locus_tag="RHX21_002685"
                     /EC_number="3.4.17.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="muramoyltetrapeptide carboxypeptidase"
                     /protein_id="HDV1987846.1"
                     /translation="MSLFHLIAPSGYCIKQHAALRGIHRLTDEGHQVNNVEVIARRCE
                     RFAGTETERLEDLNSLARLTTPNTIVLAVRGGYGASRLLADIDWQALVARQQHDPLLI
                     CGHSDFTAIQCGLLAQGNVITFSGPMLVANFGADELNAFTEHHFWLALRNKTFTIEWQ
                     GEGPTCQTEGTLWGGNLAMLISLIGTPWMPKIENGILVLEDINEHPFRVERMLLQLYH
                     AGILPRQKAIILGSFSGSTPNDYDAGYNLESVYAFLRSRLSIPLITGLDFGHEQRTVT
                     LPLGAHAILNNTREGTQLTISGHPVLKM"
     gene            12713..13324
                     /gene="emtA"
                     /locus_tag="RHX21_002686"
     CDS             12713..13324
                     /gene="emtA"
                     /locus_tag="RHX21_002686"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309714.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     EmtA"
                     /protein_id="HDV1987847.1"
                     /translation="MKLRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQ
                     KAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQLKASTSGRDVYRRMGWSGEP
                     TTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSD
                     RKKAISKINDLDADEFLDHVARNHPAPQAPRYIYKLEQALDAM"
     gene            complement(13326..14060)
                     /locus_tag="RHX21_002687"
     CDS             complement(13326..14060)
                     /locus_tag="RHX21_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar brake protein"
                     /protein_id="HDV1987848.1"
                     /translation="MSHYHEQFLKQNPLAVLGVLRDLHKAAIPLRLSWNGGQLISKIL
                     AITPDKLVLDFGSQAEDNIAVLKAQHITITAETQGAKVEFTVEQLQQSEYLQLPAFIT
                     VPPPTLWFVQRRRYFRISAPLHPPYFCQTKLADNSTLRFRLYDLSLGGMGALLETAKP
                     AELQEGMRFAQIEVNMGQWGVFHFDAQLISISERKVIDGKNETITTPRLSFRFLNVSP
                     TVERQLQRIIFSLEREAREKADKVRD"
     gene            14261..14515
                     /locus_tag="RHX21_002688"
     CDS             14261..14515
                     /locus_tag="RHX21_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDV1987849.1"
                     /translation="MGIIAWIIFGLIAGIIAKLIMPGRDGGGFFLTCILGIVGAVVGG
                     WLATMFGIGGSISGFNLHSFLVAVVGAILVLGIFRLLRRE"
     gene            14693..15133
                     /locus_tag="RHX21_002689"
     CDS             14693..15133
                     /locus_tag="RHX21_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987850.1"
                     /translation="MIQKINILDSSQSGVKNGADSEAVLAALIEHLELINPSGRLSQN
                     TRSAMLQLREEEWSEFFFWLLNSLECLDYVIINLTPESKKTLMSEHRNNIQVAIDALY
                     SQRRRKSPGDESETLTRRNDAIFGNHVWQTFAQYFPPGLEKPSV"
     gene            complement(15212..16909)
                     /gene="treA"
                     /locus_tag="RHX21_002690"
     CDS             complement(15212..16909)
                     /gene="treA"
                     /locus_tag="RHX21_002690"
                     /EC_number="3.2.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalase"
                     /protein_id="HDV1987851.1"
                     /translation="MKSPAPSRPQKMALIPACIFLCFAALSVQAEETPVTPQPPDILL
                     GPLFNDVQNAKLFPDQKTFADAVPNSDPLMILADYRMQQNQSGFDLRHFVNVNFTLPK
                     EGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPEPYVVPGGRFREVYYWD
                     SYFTMLGLAESGHWDKVADMVANFAHEIDTYGHIPNGNRSYYLSRSQPPFFALMVELL
                     AQHEGDAALKQYLPQMQKEYAYWMDGVENLQAGQQEKRVVKLQDGTLLNRYWDDRDTP
                     RPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPHQLNTLRTTSIVP
                     VDLNSLMFKMEKILARASKAAGDNAMANQYETLANARQKGIEKYMWNDQQGWYADYDL
                     KSHKVRNQLTAAALFPLYVNAAAKDRANKMATATKTHLLQPGGLNTTSVKSGQQWDAP
                     NGWAPLQWVATEGLQNYGQKEVAMDISWHFLTNVQHTYDREKKLVEKYDVSTTGTGGG
                     GGEYPLQDGFGWTNGVTLKMLDLICPKEQPCDNVPATRPTVKSATTQPSTKEAQPTP"
     gene            complement(17229..18647)
                     /gene="dhaM"
                     /locus_tag="RHX21_002691"
     CDS             complement(17229..18647)
                     /gene="dhaM"
                     /locus_tag="RHX21_002691"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415716.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaM"
                     /protein_id="HDV1987852.1"
                     /translation="MVNLVIVSHSSRLGEGVGELARQMLMSDSCKIAIAAGIDDPQNP
                     IGTDAVKVMEAIESVADADHVLVMMDMGSALLSAETALELLAPKIAAKVRLCAAPLVE
                     GTLAATVSAASGADIDKVIFDAMHALEAKREQLGLPSSDTKISDTCPAYDEEARSLAV
                     VIKNRNGLHVRPASRLVYTLSTFNADMLLEKNGKCVTPESINQIALLQVRYNDTLRLI
                     AKGPEAEEALIAFRQLAEDNFGETEEVAPPTLRPVPPVSGKAFYYQPVLCTVQAKSTL
                     TVEEEQDRLRQAIDFTLLDLMTLTAKAEASGLDDIAAIFSGHHTLLDDPELLAAASEL
                     LQHEHCTAEYAWQQVLKELSQQYQQLDDEYLQARYIDVDDLLHRTLVHLTQTKEELPQ
                     FNSPTILLAENIYPSTVLQLDPAVVKGICLSAGSPVSHSALIARELGIGWICQQGEKL
                     YAIQPEETLTLDVKTQRFNRQG"
     gene            complement(18658..19290)
                     /gene="dhaL"
                     /locus_tag="RHX21_002692"
     CDS             complement(18658..19290)
                     /gene="dhaL"
                     /locus_tag="RHX21_002692"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase ADP-binding subunit
                     DhaL"
                     /protein_id="HDV1987853.1"
                     /translation="MSLSRTQIVNWLTRCGDIFSTESEYLTGLDREIGDADHGLNMNR
                     GFSKVVEKLPAIADKDIGFILKNTGMTLLSSVGGASGPLFGTFFIRAAQATQARQSLT
                     LEELYQMFRDGVDGVISRGKAEPGDKTMCDVWVPVVESLRQSSEQNLSVPVALEAASR
                     IAESAAQSTITMQARKGRASYLGERSIGHQDPGATSVMFMMQMLALAAKE"
     gene            complement(19301..20371)
                     /gene="dhaK"
                     /locus_tag="RHX21_002693"
     CDS             complement(19301..20371)
                     /gene="dhaK"
                     /locus_tag="RHX21_002693"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415718.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HDV1987854.1"
                     /translation="MKKLINDVQDVLDEQLAGLAKAHPSLTLHQDPVYVTRADAPVAG
                     KVALLSGGGSGHEPMHCGYIGQGMLSGACPGEIFTSPTPDKIFECSMQIDGGEGVLLI
                     IKNYTGDILNFETATELLHDSGVKVTTVVIDDDVAVKDSLYTAGRRGVANTVLIEKLV
                     GAAAERGDSLDACAELGRKLNNQGHSIGIALGACTVPAAGKPSFTLADNEMEFGVGIH
                     GEPGIDRRSFSSLDQTVDEMFDTLLENGSYHRTLRFWDYQQGSWQEEQQTKQPLQSGD
                     RVIALVNNLGATPLSELYGVYNRLTTRCQQAGLTIERNLIGAYCTSLDMTGFSITLLK
                     VDDETLALWDAPVHTPALNWGK"
     gene            20599..22518
                     /gene="dhaR"
                     /locus_tag="RHX21_002694"
     CDS             20599..22518
                     /gene="dhaR"
                     /locus_tag="RHX21_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415719.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase operon
                     transcriptional regulator DhaR"
                     /protein_id="HDV1987855.1"
                     /translation="MSGAFNNDGRGISPLIATSWERCNKLMKRETWNVPHQAQGVTFA
                     SIYRRKKAMLTLGQAALEDAWEYMAPRECALFILDETACILSRNGDPQTLQQLSALGF
                     NDGTYCAEGIIGTCALSLAAISGQAVKTMADQHFKQALWNWAFCATPLFDSKGRLTGT
                     IALACPVEQTTAADLPLTLAIAREVGNLLLTDSLLAETNRHLNQLNALLESMDDGVIS
                     WDEQGNLQFINAQAARVLRLDATASQGRAITELLTLPAVLQQAIKQAHPLKHVEATFE
                     SQHQFIDAVITLKPIIETQGTSFILLLHPVEQMRQLMTSQLGKVSHTFAHMPQDDPQT
                     RRLIHFGRQAARSSFPVLLCGEEGVGKALLSQAIHNESERAAGPYIAVNCELYGDAAL
                     AEEFIGGDRTDNENGRLSRLELAHGGTLFLEKIEYLAVELQSALLQVIKQGVITRLDA
                     RRLIPIDVKVIATTTADLAMLVEQNRFSRQLYYALHAFEITIPPLRMRRGSIPALVNN
                     KLRSLEKRFSTRLKIDDDALARLVSCAWPGNDFELYSVIENLALSSDNGRIRVSDLPE
                     HLFTEQATDDVSATRLSTSLSFAEVEKEAIINAAQVTGGRIQEMSALLGIGRTTLWRK
                     MKQHGIDAGQFKRRV"
     gene            complement(22618..25503)
                     /locus_tag="RHX21_002695"
     CDS             complement(22618..25503)
                     /locus_tag="RHX21_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pertactin family autotransporter"
                     /protein_id="HDV1987856.1"
                     /translation="MGIKQHNGNTKADRLAELKIRSPSSQLIKFGAIGLNAIIFSPLL
                     IAADTGSQYGTNITINDGDRITGDTADPSGNLYGVMTPAGNTPGNINLGNDVTVNVND
                     ASGYAKGIIIQGKNSSLTANRLTVDVVGQTSAIGINLIGDYTHADLGTGSTIKSNDDG
                     IIIGHSSTLTATQFTIENSNGIGLTINDYGTSVDLGSGSKITTDGSTGVYIGGLNGNN
                     ANGAARFTATDLTIDVQGYSAMGINVQKNSVVDLGTNSTIKTNGDNAHGLWSFGQVSA
                     NALTVDVTGAAANGVEVRGGTTTIGADSHISSAQGGGLVTSGSDATINFSGTAAQRNS
                     IFSGGSYGASAQTATAVVNMQNTDITVDRNGSLALGLWALSGGRITGDSLAITGAAGA
                     RGIYAMTNSQIDLTSDLVIDMSTPDQMAIATQHDDGYAASRINASGRMLINGSVLSKG
                     GLINLDMHPGSVWTGSSLSDNVNGGKLDVAMNNSVWNVTSNSNLDTLALSHSTVDFAS
                     HGSTAGTFATLNVENLSGNSTFIMRADVVGEGNGVNNKGDLLNISGSSAGNHVLAIRN
                     QGSEATTGNEVLTVVKTTDGAASFSASSQVELGGYLYDVRKNGTNWELYASGTVPEPT
                     PNPEPTPAPAQPPIVNPDPTPEPDPTPNPTPTPKPTTTADAGGNYLNVGYLLNYVENR
                     TLMQRMGDLRNQSKDGNIWLRSYGGSLDSFASGKLSGFDMGYSGIQFGGDKRLSDVMP
                     LYVGLYIGSTHASPDYSGGDGTARSDYMGMYASYMAHNGFYSDLVVKASRQKNSFHVL
                     DSQNNGVNANGTANGLSISLEAGQRFNLTPTGYGFYIEPQTQLTYSHQNEMAMKASNG
                     LNIHLNHYESLLGRASMILGYDITAGNSQLNMYVKTGAIREFSGDTDYLLNNSREKYS
                     FKGNGWNNGVGVSAQYNKQHTFYLEADYTQSNLFDQKQVNGGYRFSF"
BASE COUNT         6365 a         6371 c         6622 g         6376 t
ORIGIN      
        1 ctaattcata gttagccggg cgggatgcgt caatgtcttt atttctatta atatgataaa
       61 tatcaaacaa tgtttaatgt cattatggcg aatgcttcta ttctattttt ttgccgggtg
      121 atatttttca tttctgctgg atgagcgtcg tcgccagaag gccacgtgag cacaggataa
      181 gagaacgaaa aatcagcagt ctatgcagcg acaaatattg atagcctgaa tcagtattga
      241 tctgctggca agaacagact gctgtatata aaaacagtat aacttcaggc agattattat
      301 gttgtttatc aagcctgcgg atctccgcga aattgtgact tttccgctat ttagcgatct
      361 tgttcagtgt ggctttcctt caccggcagc agattacgtt gaacagcgca tcgatctgaa
      421 tcaactgttg atccagcatc ccagcgcgac ttacttcgtc aaagcaagtg gtgattctat
      481 gattgatggt ggaattagtg acggtgattt actgattgtc gatagcgcta ttaccgccag
      541 ccatggtgat attgtcatcg ctgctgttga cggcgagttt acggtgaaaa aattgcaact
      601 acgcccgacg gtacagctta ttcccatgaa cagtgcgtac tcgcccatta ccatcagtag
      661 cgaagatacg ctggatgtct ttggtgtggt gatccacgtc gttaaggcga tgcgctgatg
      721 tttgctctct gtgatgtaaa cgcgttttat gccagctgtg agacggtgtt tcgccctgat
      781 ttatggggta aaccggtggt tgtgctatcg aataatgacg gttgcgttat cgcccgaaac
      841 gctgaggcaa aggcgctggg tgttaaaatg ggcgatccct ggttcaaaca aaaagatctg
      901 tttcgtcgct gtggcgtggt ttgctttagc agcaattatg agctttacgc agacatgagc
      961 aatcgggtga tgtcgacgct ggaagaacta tcgccccgcg tcgagattta cagtattgat
     1021 gaggcattct gcgatctgac aggtgtgcgt aattgtcgcg atctgactga ttttggcaga
     1081 gaaattcgcg caacggtgct acaacgtacc catcttactg ttggtgtggg gatcgcccag
     1141 accaaaacgt tggctaagct tgccaatcat gcggcaaaaa aatggcagcg gcagacgggt
     1201 ggggtggtgg atttatcaaa tctggaacgc cagcgtaaat taatgtctgc tctccccgtg
     1261 gatgacgtct gggggattgg acggcggatc agcaaaaaac tggacgcgat ggggatcaaa
     1321 accgttcttg atttggcgga tacagatatc cggtttatcc gtaaacattt taatgtcgtg
     1381 ctcgaaagaa cggtgcgtga actgcgcggc gaaccctgtt tgcaactgga agagtttgca
     1441 ccgacgaagc aggaaattat ctgttcccgc tcgtttggtg aacgcatcac ggattatcca
     1501 tcgatgcggc aggccatttg tagttacgct gcccgggcgg cggaaaaact tcgcagcgag
     1561 catcaatatt gtcggtttat ctccacgttt attaagacgt caccatttgc gctcaatgaa
     1621 ccttattacg gcaatagcgc gtcggtaaaa ctgctgacgc ccactcagga cagcagggat
     1681 atcattaacg ctgctacgcg atctctggat gccatctggc aagcgggcca tcgctaccaa
     1741 aaagcgggcg tgatgctggg ggatttcttc agtcagggag tcgcgcagct caatttattc
     1801 gatgacaacg caccgcgccc cgggagtgag caattgatga cggtaatgga tacactgaat
     1861 gctaaagagg gcagaggaac actctatttt gccgggcagg ggatccagca acaatggcag
     1921 atgaagcgtg ccatgctttc accacgttat acaacgcgaa gttctgattt actgcgggtc
     1981 aaataaatat agcggcagga aaaaagcgct cccgcaggag cgccgaaggg attagcgacc
     2041 gaacaggtca cgttttttcg ctttaaacgg ctgggaaatc accaccagca ccgcgacaat
     2101 caggtaagcg ataaaaatac cgagcagcca ctgcggcatt tccagaccta aaaaatccca
     2161 ctgacgctcg gcacaatcgc cagaggcgac aaacacttgc ggcacccatt tatccagcgg
     2221 cagccattcc gggaaacgaa ccataaaatc acaggtggca aacggcgaag gatagagctg
     2281 aagcatggtg tgctcgtaag ttaactgcac accgcggaac gcactataca accagataac
     2341 catcgctaca taacgcagcg gagttttcgg ggcgatcgcg ccaatcagcg cagcacccag
     2401 aacgccgaat aacgcacaac gttcataaat acagagcacg caaggtttca gtaacatcac
     2461 atgctggaac cacagcgccg tcagttccag tgccagagca gtaaacgcca tcaacagcca
     2521 cgcgccccgg ccttgtgaac attggttcaa aaatcgcaac ataatcattt ccctgcaata
     2581 tgcatagagt gcgcagttta aaccaattca ttcgctgcgc caccaggagg cagcaaaaat
     2641 aggaagcaat tggacaatta tcgggcgaaa aggcaaaccg ggcatttata tgcccggtaa
     2701 gttgttatca aagcgttgct atccagccca tttgcataaa ccattcggtt acaggggcaa
     2761 gcgtaaactc gacgcagagc aagccgacga gtgtcagtac gagggtgtaa ggcagggcca
     2821 tccacaccat gcggccataa gagaggcgaa tcaatggcgc gagtgcagag gtcagcagga
     2881 acaggaacgc agcctgaccg ttcggcgtag cgacggaggg cagattggta ccggtattaa
     2941 tggcgaccgc cagcagctcg tattgcttca acgtgatagc gccactttcc attgccgctt
     3001 tcgcttcgtt gatataaatc gtccccacga agacgttatc cgaaatggat gacagcagac
     3061 cgttgaaaat atagaacagc gacagctgag catgttccga tgcctgcaac acaaactgaa
     3121 taattggcga aaacagttgt tggtcgataa tcaccgcgac taccgagaaa aacaccgtca
     3181 acagtgcggt gaatggcaga gattcggtga aggctttacc gatagcatgt tcatcggtga
     3241 caccggtcaa tgatgtcgcc agaataatga ctgacaaacc aatcaagcca acttccgcca
     3301 gatgcaacgc cagcgcagtc accagccaga cgccaataat cgcctggaca atcagacgga
     3361 ttttatcctg acgggtacgc tggtggcggc tttgatcgtc aaactgttgc aacacttcgc
     3421 ggactttctc cggcagcgtt tcaccgtagc caaaccaacg cagcttctct accagcaggc
     3481 aggttaacag gccacaaatc agaaccggaa cggtcaccgg cgacatgcgc aggaagaaat
     3541 cgccaaaatg ccagccagcc gctttagcga tgatcaggtt ctgtggttcg cccaccatgg
     3601 tcatcacgcc gcctaatgca gtgccgacac cggcatgcat catcaggcta cgcagaaagc
     3661 cacggaactg ttccagaacc actttgtaat gcttgtcgat atgactatcg tcttgcaggt
     3721 cggtatcttc agtacgggaa gaggctacgc ggtgataaat accataaaaa ccgactgcaa
     3781 cgctgatcac caccgccacg acggttaagg catcgaggaa cgcggagagg aacgccgccg
     3841 ccacgcaaaa agagagcgac agcagcattt tggagcgaat gcttaacagc aaacgggtaa
     3901 atatgaacag caatagctgt ttcataaaat agatacccgc caccataaac atcagtaaca
     3961 gcaagacttc aagatttgcc gccacctctt cacggacgtg ttccgcgctg gtcatgccga
     4021 tgaataccgc ttcgatagcc aacagaccac cggggagcag cgggtagcat ttcagggcca
     4081 tcgccagagt gaaaataaat tccgctacca gcaaccagcc cgcgacgaaa gggctgatga
     4141 ggaaaattaa cgggtttacg attaagaaaa tgatgagggc gagtttgtac cagtcggggg
     4201 actggcccaa aaaattgcgc catagcgcgc ggccccagga gatctccatg atggtttccc
     4261 ttaccttaca aataatcaat gatgttttta tgtttaaacg caaagcttaa cggtcaggca
     4321 ggagtgaggc aagtcttgat agtcaagggg aaagagatgc ggaaaatgaa gccttgatcc
     4381 cttttttctt ctttttgtct gctatcagcg tagttagccc tctggtatga tgagtccaac
     4441 tttgttttgc tgtgttatgg aaatctcact atggtcatta aggcgcaaag cccggcgggt
     4501 ttcgcggaag agtacattat tgaaagtatc tggaataacc gcttccctcc cgggactatt
     4561 ttgcccgcag aacgtgaact ttcagaatta attggcgtaa cgcgtactac gttacgtgaa
     4621 gtgttacagc gtctggcacg agatggctgg ttgaccattc aacatggcaa gccgacgaag
     4681 gtgaataatt tctgggaaac ctctggttta aatatccttg aaacactggc gcgactggat
     4741 cacgaaagtg tgccgcagct tattgataat ttgctgtcgg tgcgtaccaa tatttcaact
     4801 atttttattc gcaccgcgtt tcgtcagcat cccgataaag cgcaggaagt gctggctacc
     4861 gctaatgaag tggccgatca cgccgacgcc tttgccgagc tggattacaa catattccgc
     4921 ggcctggcgt ttgcttccgg caacccgatt tacggtctga ttcttaacgg gatgaaaggg
     4981 ctgtatacgc gtattggtcg tcactatttc gccaatccgg aagcgcgcag tctggcgctg
     5041 ggcttctacc acaaactgtc ggcgttgtgc agtgaaggcg cgcacgatca ggtgtacgaa
     5101 acagtgcgtc gctatgggca tgagagtggc gagatttggc accggatgca gaaaaatctg
     5161 ccgggtgatt tagccattca ggggcgataa tcccttccgt ttaaagagca accccctcaa
     5221 acgaggggtt ttttgttgtt tttacagatt tcccattctt ggcgggcaac gttccagcaa
     5281 ctcgatgctg ccgtcttcgt tttgctgttc gagcatcaca tcaaatcccc acaggcgatg
     5341 cacatgcttc agcacttctt tgcgcccccg atccagcggt gcgcgattat gtggaatgta
     5401 acgcagcgtc agcgaacggt cgccgcgcaa atccacgttc cagatctgaa tattcggctc
     5461 cagattactt aagttatatt gcgacgataa ccggttacgg atctcccgat aaccttcttc
     5521 attatgaata gcggaaatct ccagataatt atgccgatca tcatccagca cggtgaagaa
     5581 gcggaaatca cgcatcactt tcggtgacag aaactggctg ataaaactct catctttgaa
     5641 atcacgcatc gcgaaatgca gcgtttccag ccagtcggaa ccggcgatat ccgggaacca
     5701 gtatttgtct tcttccgttg gcgactgaca aatccgttta atatcctgga acatggcgaa
     5761 cccgagggca tacgggttga tgccgctgta ccacgggctg ttataggggg gctggaagac
     5821 cacattggtg tggctgtgca aaaactccag cataaaacgt tccgttactt tcccttcatc
     5881 atacagatgg ttaaggatgg tatagtgcca gaaggtcgcc cagccttcgt tcatcacctg
     5941 agtctgtttt tgcggataaa aatactggct caccttacgc acaatacgca ggatttcacg
     6001 ctgccatgat tccagcagtg gcgcattttt ctccataaaa tagagcaggt tttcttgtgg
     6061 ttcggacgga tagcggcgcg cttcagcaac cgttttctct tcctcgcgct tcggcagggt
     6121 acgccagagc atattgacct gactttgtag atactcttcg cgacttttct gccgggcttt
     6181 ctcttcttgc agcgagattt tttgcgggcg tttgtaccgg tccacgccgt agttcatcag
     6241 cgcgtggcac gagtccagaa gccgttctac ttcatcaacg ccataacgtt cttcgcactc
     6301 ggtaatatat ttacgggcaa aaatcagata atcgacaatc gaactggcgt cggtccaact
     6361 gcggaataag taattgtttt taaagaaaga gttatgccca tagcaggcgt gtgccatcac
     6421 cagcgcctgc atggtaatgg tgttctcttc catcaggtaa gcgatacacg ggttagagtt
     6481 aatgacgatt tcataggcca gtccttgctg accgtgctta tacagccgtt cagtctcgat
     6541 aaacttttta ccgaatgacc agtgcggata gttaattggc atgccgacgc tggagtaggc
     6601 atccatcatc tgttctgagg ttatcacttc aatctggtgc gggtaggtat ccagccggta
     6661 gagtttcgcc acccggtcta tctctgccag ataaacatcc agcaggtcga acgtccagtc
     6721 gggtccatcg ctcaaacgtg tggtgtcctt attcatagaa tcgatcgtcg ccatacgcgc
     6781 acctcattgt tgtcggcgct ctctgtgtgg agcacctcat ttcaagcata gaacacctgt
     6841 taaaaaccgc gtcgccggag aatttttttc tttgcgattt cttattatca gagtgccact
     6901 aatccgcttc tgaacggaat tttatgctgg ataaaaaggg cgttcagcag gagatactaa
     6961 agacgccata ttgccgcaga gtcagggaga tgtgagccag ctcaccataa aaaagccgta
     7021 tgttgaataa tattttcaac tgagttatca agatgtaatt agattattat tcttttactg
     7081 tatctaccgt tatcggagtg gctatgcgag ttgtcatact gggaagtggt gtggtaggcg
     7141 ttgccagcgc ctggtactta aatcaggcag gacatgaggt caccgtcatt gatcgggagc
     7201 cgggggccgc cctggaaacc agtgccgcga atgccgggca aatctccccc ggatatgctg
     7261 caccgtgggc ggcaccaggt gtgcctttaa aagcgattaa atggatgttc cagcgccatg
     7321 cgccgctggc ggttcgtctc gacggtacgc agttccagtt gaaatggatg tggcaaatgt
     7381 tacgtaactg cgacaccagc cactacatgg aaaacaaagg gcggatggtg cgtctggcgg
     7441 aatacagccg tgattgcctg aaagcattgc gcgccgaaac caatattcag tatgaagggc
     7501 gtcagggtgg gacgctgcaa ctgttccgta ccgaacaaca gtatgaaaat gcgacccgcg
     7561 atatcgccgt gctggaagat gccggcgtac cgtatcagct gctggaatcc agccgcctgg
     7621 cggaagtgga gcccgcgctg gcagaagtgg cgcacaaact gacgggcggc ctgcagttac
     7681 ccaatgatga aaccggagac tgtcagctat ttacccagaa tctggcgcgg atggcggagc
     7741 aggcgggggt taaattccgc tttaatacgc ccgttgacca actgctttgc gacggcgagc
     7801 aaatctacgg cgtgaagtgt ggcgatgaag tgattaaggc cgatgcgtat gtgatggcgt
     7861 ttggttctta ctcgacggcg atgctcaaag gcattgttga tattccggtg tatccgctga
     7921 aaggctactc gctgactatt ccaattgcgc aggaagatgg tgcgccagta tccactattc
     7981 ttgatgaaac ctacaaaatc gccattaccc gtttcgataa ccgcattcgt gttggcggaa
     8041 tggcggaaat tgttggtttt aacaccgagc tgttgcaacc gcgtcgtgaa acgctggaaa
     8101 tggtggttcg cgatctctat ccacgcggcg gtcatgtcga gcaggcgact ttctggacgg
     8161 gtttgcgccc gatgacgcca gacggtacgc cggttgtcgg gcgtacacgc tttaaaaatc
     8221 tgtggctgaa taccggtcac ggcacgctcg gctggacgat ggcttgcggt tccggtcagt
     8281 tgttaagcga tctgctctct ggtcgcacgc cagcgatccc atatgaggat ctaagcgtag
     8341 cgcgctacag ccgtggattt acgccatcac gtccgggcca tttacatggc gcacacagct
     8401 aaggaaacga gatgacccgt ccgatacagg ccagcctcga tctgcaggca ttaaaacaga
     8461 atctgtccat tgtccgccag gccgcgccgc acgcgcgcgt ctggtcggtg gtaaaagcga
     8521 acgcttacgg gcatggtatt gagcgtatct ggagcgcgct cggggccacc gatggctttg
     8581 cattacttaa cctggaagag gcaataacgt tacgtgagcg cggctggaag gggccgatcc
     8641 tgatgctgga aggatttttc catgctcagg atctggagat ttatgaccag caccgcctga
     8701 ccacctgcgt acacagcaac tggcagctca aagcactgca aaatgcgcgg ctaaaagcac
     8761 cgttggatat ttatcttaaa gtgaacagtg ggatgaatcg gttgggcttc cagcccgatc
     8821 gcgtgcttac cgtctggcag cagttgcggg caatggcgaa tgttggcgag atgaccctga
     8881 tgtcgcattt tgccgaagcg gaacatcctg atggaatttc cagcgcgatg gcgcgtattg
     8941 agcaggcggc ggaagggctg gagtgtcggc gttcgttgtc caattcggcg gcgactctgt
     9001 ggcacccgga agcgcatttt gactgggttc ggcctggcat tattttgtat ggcgcttcgc
     9061 cgtccggtca gtggcgtgat atcgccaata ccggattacg tccggtgatg acgctaagca
     9121 gtgagattat tggtgtccag acgctaaaag cgggtgagcg tgtgggctac ggcggtcgct
     9181 atactgcgcg cgatgaacag cgaatcggca ttgtcgccgc agggtacgcc gacggttatc
     9241 cgcgccacgc gcctaccggt acccctgttt tagtggacgg cgtgcgcact atgacggtgg
     9301 ggaccgtctc gatggatatg ctagcggtcg atttaacgcc ttgcccgcag gcggggattg
     9361 gtacgccggt tgagctgtgg ggcaaggaga tcaaaattga tgatgtcgcc gccgctgccg
     9421 gaacggtggg ctatgagttg atgtgcgcgc tggcgttacg cgtcccggtt gtgacagtgt
     9481 aacttgttgt aagccggatc ggagacagcg tcttctggtt gcgaaaaaat catcaatccg
     9541 gctggtcagc aactgtagtt gttaatgtga cagagccatt gcccatgata gtgtccatta
     9601 aaagaatgga cactatttcc ccggaacctg aactcaccgc acaggcgttc tacataaaac
     9661 gcttacgctt cattgttgac tcgaactcga cttcagataa atcacgcttt acccttgatg
     9721 gagcctgtac atagatttgt gtaattgcct gattttgata tgttcaattc aacatcaaat
     9781 gaaggttaaa ttatggacga caaacaattg caggctcagg ctgcgttcag caaagcatcg
     9841 caaccggcga tagatgcttc attaaattta agattcagct tcctcttcag ccacccgtac
     9901 gccaatcttc aacacttcat tatcttcttt ctcggccacc gtccagatca tcccggcaaa
     9961 ctctacctgg tcaccgacaa ccggtgccgc gcctaacaac tgctggacaa tttcacccag
    10021 cgtttgctgc ttatcacgat attctcgccc gtcttccagg ccatatatca gcgcaacatc
    10081 agcatatttg gcgctggctt cgagaatgaa gtcaccaaag aagcgttgat ccagcgcgac
    10141 cggcggcgac tggctgaaca gtttaccgag cgccggaaga tcgcgttccc gaccaattac
    10201 acacaacaca tcgccttcgc gcagtcgggt gctgccggta ggatgaagca actggttatc
    10261 acgaaacagt gccgcaatac gcgtctcttt tggcatatgc aaatcgcgca gtgccgcgcc
    10321 cacgcaccat ttatcggcac tcaattgata aacaaactgc tcccacggat tttccggatg
    10381 aatatccagg ccaacgcgtg acaccggacg tcccactggc ggaaccacca ctttggcttt
    10441 tttagccgcc cacgagagtg atgttccctg caagagcagt gaaaccagaa ccacaaagaa
    10501 ggcgacatta aagaacagac gtgcattctc cagccccgcc atcatcggga acacggccag
    10561 gatgattggc accgcgccgc gtaatcctac ccagctgata aacacgcgct cacgcagatt
    10621 gaaaccgcgg aaggggagca atccagcaaa taccgaaagg ggacgggcga agaatatcat
    10681 ccatgccgac aaaatgagcg ccggaatggc aataggcagc agatcgcttg ggttaaccaa
    10741 tagccccagc accaggaaca tggcgatttg cgccagccag gcgaggccgt cgaaattttg
    10801 caggatgccg tagcggttgc gaatcggccg attacccagc agaaaaccgc acagataaac
    10861 agccagaata ccgctgcctt ccagcgccgt ggttaaagca aaaattaaaa taccgccgct
    10921 taatgccagc aatggatata atccggcagg cagggcgatg cgattaatca tttgcagcag
    10981 taaataatca ccgccaagtc cgatgacaat cccgaggcca aattgctgca gaatatcgac
    11041 cacgaacatc caactgacac tgctttcatg ttgctggatc atcgcaatca gggtaatcgt
    11101 cagaaagacc gccattggat cattactgcc ggattcaatt tccagcgtcg agccaacacg
    11161 ttcgttaagc cccttaccac ccagcagaga aaagaccgct gcagcatcgg tagagccgac
    11221 gatagcgccg attaataagc cttcaatcaa atcaagatta aacagccacg ccgccatcat
    11281 gccggttaaa ccagaggtga taagcacgcc cagcgtcgcc agcgacagtg ccggtcctaa
    11341 cgccacacga aaggaactgg cctgagtgcg catcccgccg tcgagcaaaa taatcgccag
    11401 tgccaggtta cttaccatgt aggcgaaggg gtaattatca aacgggatac cgccgacgcc
    11461 atcgactcct gccagcatgc cgatcgccag aaaaataacc agaataggaa tgccaagacg
    11521 ggaagaaaat gaactaagta atatactgct ggtgacaagg atggatccta agatgaaaag
    11581 gctaattatt gttgtggcat ccaacggtcg gttactcctg attacgctgt ctcttatata
    11641 aaccctacca tattagcggc agagacagcg ttttacttag ccctgaagcg tgattttttt
    11701 acattttaag aacaggatga ccgctaatcg tcaactgagt gccttcccgg gtgttattca
    11761 gaatggcatg tgcgcccaac ggcagcgtaa ccgtgcgttg ttcatgacca aaatcgaggc
    11821 cggtaatgag tggaatcgac aggcgggaac gcaaaaacgc gtacactgac tccaggttgt
    11881 aacctgcgtc ataatcattg ggcgtgctgc cgctaaagct accgagaata atcgccttct
    11941 gacgtggcaa aattcccgca tgatagagct gcaacagcat acgttcgacg cggaaagggt
    12001 gctcgttaat atcttccagc accagaatac cgttctcaat ttttggcatc cacggtgtac
    12061 caatcagtga aatcagcatc gcaagattgc ctccccacaa cgtgccttcg gtctgacatg
    12121 tcgggccttc cccttgccat tcaatggtga aggttttatt gcgtaacgcc agccagaaat
    12181 ggtgctcggt aaaggcgttc agttcatccg caccaaagtt tgctaccagc atggggccgc
    12241 taaaggtgat gacattgcct tgcgccagaa gaccgcactg aatggcggta aaatcgctat
    12301 gtccgcaaat gagtaacggg tcatgttgtt ggcgagcaac cagtgcctgc cagtcaatat
    12361 ctgccagtaa acgactggca ccgtaaccgc cgcgtacagc cagcacgatg gtgttggggg
    12421 tagtcagtct ggcaagggaa ttgagatctt ccaggcgctc cgtttccgta cccgcaaaac
    12481 gctcacaacg acgggcaata acctcgacgt tattgacctg atgcccctcg tcggtaaggc
    12541 gatggatacc acgcagcgcg gcgtgctgtt taatgcagta acccgatggg gcaattaagt
    12601 gaaacagaga catggcaatt ccttgctgac aacagaaacg aaatgtatat catgccgctt
    12661 aggtgtgccg ttgtcacctc aacggcgatt ccaggctata aggatagaag aagtgaaatt
    12721 gagatggttt gcctttttga ttgtgttatt agcgggttgt tcatcaaagc atgactatac
    12781 gaacccgccg tggaacgcga aagttccggt gcaacgtgcg atgcagtgga tgccaataag
    12841 ccagaaagcc ggtgcagcct ggggcgtcga tccacaattg atcacggcga ttatcgctat
    12901 cgaatcgggt ggtaatccga atgcggtgag taaatcgaat gccattggtt tgatgcagtt
    12961 aaaagcttca acctccggac gtgatgttta tcgccgtatg ggctggagtg gtgagccgac
    13021 gaccagcgag ctgaaaaatc cagagcgtaa tatttcaatg ggggcggctt acctgaatat
    13081 tctggaaacc ggcccgctgg caggcattga agatccgaag gtactgcaat atgcgctggt
    13141 ggtgtcatac gctaacgggg caggtgcgct gctacggact ttctcgtcag atcggaaaaa
    13201 ggcgatcagc aaaatcaacg atttggatgc tgacgagttc ctcgatcacg tagcgcgaaa
    13261 tcatcctgcg ccgcaggctc cgcgctatat ctacaaactt gagcaggcac tggacgcgat
    13321 gtaaatcagt cgcgcacttt gtccgctttt tcccgggctt ctcgctcgag agagaaaata
    13381 atccgctgta attgccgctc caccgtcggg ctgacgttaa gaaaacggaa gctcagacgg
    13441 ggagtggtga tggtttcatt cttgccatca atcactttgc gctcgctgat ggagattaac
    13501 tgggcgtcaa agtgaaaaac accccattgc cccatgttga cttcaatctg agcgaagcgc
    13561 atgccttctt gtaattcggc aggctttgct gtttccagta atgcgcccat gccgcctaac
    13621 gacaaatcat acaggcggaa acgtaacgta ctgttatccg ccagtttggt ctggcaaaaa
    13681 taaggcggat ggagtggggc ggagatgcgg aaatatcggc gtcgttgtac aaaccataag
    13741 gtgggaggcg gtacggtgat aaatgccgga agctgcaagt attcactctg ctgtagttgt
    13801 tcaacagtaa actcgacttt cgcaccctga gtttcggcgg taatggtaat gtgctgtgcc
    13861 tttagcacgg cgatgttgtc ttcggcttga ctgccgaaat ccagcaccag tttatccggg
    13921 gttattgcca gtattttgct gatcagctgc ccgccattcc aactgagacg caaaggaatt
    13981 gcggctttgt gcaaatcgcg taacacgccc aggacggcta acggattttg tttcaggaac
    14041 tgctcatggt aatgactcac gcggaaaaac tcctgactga caaactgtct ttggtttatc
    14101 ggtcacagtt aacaaaactt aatacaaatg cgtgaatatt ttttacatgt tgttcttaaa
    14161 tcagccgaca tacgcccagc atcgatcccg cccttgccta tacttagagc gttgacgtaa
    14221 gcatttcttg cgtccgattc atcgaaacga gggcctgaac atgggaatta ttgcctggat
    14281 tatttttggc ctgatagccg gcattatcgc caagctaatc atgccggggc gtgatggtgg
    14341 tggatttttc ctgacctgta ttctcgggat agtcggtgcg gtggtcggcg gctggctggc
    14401 gaccatgttt ggcattggcg gctccatcag tggttttaat ctgcacagct tcttggtggc
    14461 ggtggtggga gctattctcg ttctgggcat attccgcctc ctgcgaagag aataagattt
    14521 tcataaggcg gatagcgata cagatgccgc tatccgcttt cacatcagaa cgtatactcg
    14581 acacctgctt tacgggtgaa aaaaatcaat atagcacttc gatatccgat aaagtcggtt
    14641 cccggtaaca acaacagaat ccttttttaa ttattgtttc gttgtttttg gtgtgattca
    14701 gaaaataaat attttagaca gtagccagtc aggcgttaaa aatggggcgg atagtgaggc
    14761 ggttttggct gcgcttattg aacatttaga attgatcaat ccttctggca gattaagcca
    14821 aaatacccgt tcggcaatgc ttcagttacg cgaagaggaa tggtctgaat tctttttttg
    14881 gttgctaaat tctctggagt gtctggatta tgtgattatt aatttaactc cagaaagcaa
    14941 aaaaacgttg atgagtgaac accgtaacaa tattcaggta gcaattgatg ctttatatag
    15001 ccaacgtcgg cgtaaatcgc cgggtgatga aagtgaaaca cttacccgta gaaatgacgc
    15061 tatcttcggc aaccacgtat ggcaaacatt tgcgcaatac ttcccgccag gacttgaaaa
    15121 accgtctgtg tagaaaaaac catagctatg gtgttatctg ccgacaacgc catccggaga
    15181 agccgaatga cgttgtcgga gtaagcgctg gttaaggtgt gggttgtgcc tctttggttg
    15241 agggttgcgt cgttgctgac ttaacggtcg gacgcgtcgc cggaacattg tcacacggtt
    15301 gctctttcgg gcagatcaaa tccagcattt tcagcgtcac gccattggtc cagccaaagc
    15361 catcctgtaa tggatattcg ccaccgccgc cccccgttcc ggtggtgctg acatcatatt
    15421 tttccaccag ctttttctcc cggtcatagg tgtgctgaac attggtcagg aagtgccagc
    15481 taatgtccat cgccacctct ttttgcccgt agttttgtaa tccttctgtc gcgacccact
    15541 gtaacggtgc ccagccattt ggcgcatccc attgttgccc acttttcacc gacgtggtgt
    15601 tcaggccgcc gggttgcagc agatgtgttt tcgtcgccgt cgccattttg ttggcgcgat
    15661 ctttcgctgc cgcattgacg tacagcggga acagggcggc cgcggttaac tgattgcgca
    15721 ctttatgact tttcaggtcg taatcggcat accagccttg ttgatcgttc cacatgtatt
    15781 tttcgatccc tttttgacgg gcatttgcca gcgtttcgta ctggtttgcc atcgcgttat
    15841 ctccggcagc tttgctggcg cgggcgagga ttttttccat tttaaacatc aggctgttca
    15901 gatcgaccgg tacgatgctg gtggtgcgta aggtatttag ttgatgcggg ttgtccatcc
    15961 agcgcgagct gaaatcccag ccagacgcag cggcagagcg caggtcgcgg taaatttcag
    16021 tggcaggtcg attcggattg cttttggcgg tggcaatatc ttccacccat gactctggtc
    16081 gtggcgtatc gcgatcgtcc cagtagcggt tgagaagggt accatcctga agttttacaa
    16141 cgcgtttttc ctgttgtccg gcttgcaggt tttcaacacc gtccatccag taagcatatt
    16201 ctttttgcat ttgcggcagg tattgcttca acgcggcatc gccttcatgc tgcgccagta
    16261 actctaccat cagggcaaag aagggcggtt gcgagcggct taaatagtaa ctgcggttgc
    16321 cgttgggaat atgaccgtaa gtgtctattt catgagcaaa attggccacc atatccgcga
    16381 ctttatccca gtgaccgctt tcggcaagtc ctaacatggt gaagtaactg tcccagtaat
    16441 atacctcgcg aaaacgtccg cccggcacga cataaggttc cggcagcggt aacagagaat
    16501 cccatttttc ggtgttttcg gtagaacgcg ttaataccgg ccaaagtccg tcaatatgtt
    16561 cgcgcagtga ctgcccctct ggcggaacat atttctcgcc ctctttcggc agggtgaaat
    16621 tgacgttaac gaaatggcgc agatcaaatc cgctctggtt ttgctgcatc cgataatcag
    16681 caaggatcat cagcggatcg ctgttcggca cggcatcggc aaaggttttt tggtccggaa
    16741 aaagtttggc gttttgcaca tcattaaaca gcggccctaa taaaatatca ggcggctgtg
    16801 gtgttaccgg tgtttcttct gcctgcaccg atagcgcagc gaaacacaaa aagatacagg
    16861 ctggaattaa cgccattttt tgcgggcgag aaggtgcggg ggatttcatc aatcattctc
    16921 ctttggcgaa accgaataaa acggtattca agtatcagaa aaccttagtt caggatcgca
    16981 ctagctgcat gatcgaaatc tcattctgcg aactgtcagg cattttagaa aagggaatta
    17041 aagggataaa taacggtgaa atagagtgat caaataacgt ctgtttatta gccagtcagc
    17101 gacgttgggt tcgcgattag cgaagaaaaa tcatcataaa ttggtaaaaa atataacagg
    17161 tagttaaaaa acatcagtgc tgggtaaatt gccggatgac atcagaacga tgccatccga
    17221 acggtggctt aaccctgacg gttgaaacgt tgcgttttaa cgtccagcgt tagcgtttct
    17281 tctggttgta tcgcatacag tttctcaccc tgctggcaaa tccagccaat ccccagttca
    17341 cgggcgatta gggcgctgtg ggataccgga cttccggcgc taaggcagat accttttaca
    17401 accgccggat ccagttgcag tactgtggaa ggataaatgt tctccgccag tagaatagtt
    17461 ggcgagttaa actgcgggag ttcttctttc gtttgggtca ggtggaccag ggtgcgatgc
    17521 agaagatcgt ccacatcaat atagcgagct tgtagatatt catcatccag ttgctggtat
    17581 tgctggctaa gttctttaag aacttgctgc caggcatatt ctgccgtgca atgttcatgc
    17641 tgaaggagtt cgcttgccgc cgccagcagt tccggatcat ctaacagtgt atggtgacca
    17701 gaaaagattg cggcaatatc gtcaagcccg ctggcttctg cttttgctgt taacgtcatc
    17761 agatctaata acgtgaagtc aatagcctgg cgtaatcgat cttgttcttc ttccacggtc
    17821 agggttgatt ttgcctgtac cgtacataaa actggttgat aataaaaggc tttacccgaa
    17881 acaggcggaa cgggacgcag agtaggtgga gcgacttcct ccgtttcacc aaagttatct
    17941 tcagccagct gacggaaagc gatcagtgcc tcttcagctt ctggcccttt cgcaatcagg
    18001 cgcagcgtat cgttatagcg aacttgtagt aacgcaatct ggttaatact ctctggtgtg
    18061 acgcatttgc cgtttttttc cagcaacata tcggcattaa atgtcgataa ggtataaacc
    18121 agccgggagg ccggacgtac atgcaggccg ttacggtttt ttatgaccac cgccagagaa
    18181 cgggcttctt catcgtacgc aggacatgtg tcagagattt tagtgtcgga ggacggtaaa
    18241 cccagttgtt cacgtttggc ttccagcgca tgcatagcgt caaagataac tttgtcgata
    18301 tccgctcccg aggccgcgct gaccgttgct gccagtgtac cttcgaccaa cggcgcagca
    18361 cacaaacgta cttttgcggc gatcttggga gccagcaatt ccagcgcagt ttcagcactc
    18421 aataatgcgc tacccatatc catcatgacc agcacatggt cggcatcagc aacagattcg
    18481 atggcctcca tcactttgac ggcatcggta ccaataggat tttgtggatc gtcaattccc
    18541 gcggcaatgg cgattttaca actatcactc attaacatct gacgggctaa ttcaccgaca
    18601 ccttctccca gtcggctgct atgtgaaact atgaccaggt ttaccatcac caattcctta
    18661 ctcttttgcg gctaacgcca acatttgcat cataaacatc accgaggtcg cgccgggatc
    18721 ctggtgacca atactgcgtt caccgagata actggcgcgg cctttgcggg cttgcatcgt
    18781 aatcgtactt tgtgcagcgg attcggcgat tctactggca gcttcgagcg ccaccggaac
    18841 agagagattt tgctcgctgg actgacgtaa cgattccacc accggcaccc acacatcaca
    18901 catggtttta tcgccaggtt cggctttccc gcgactgatt acgccgtcca cgccatcgcg
    18961 gaacatctga taaagctctt ccagtgtcag gctttgccgt gcctgggtcg cctgtgcggc
    19021 gcggataaag aaggtaccga acagcggacc actggcacca ccgacgctgg aaagcagcgt
    19081 cataccggta ttcttgagaa tgaaaccgat atctttatct gcgatagcag ggagtttttc
    19141 caccactttg ctaaagcctc ggttcatatt tagcccgtgg tcagcgtcgc caatttcgcg
    19201 atccagtccg gtaagatact cgctctcggt gctgaaaata tcgccacaac gagtgagcca
    19261 gttaacaatt tgagttctgc tcagtgacat tgctttctcc ttatttaccc cagttaaggg
    19321 ccggggtgtg gaccggggcg tcccagagtg ccagcgtttc gtcatcaact ttcagtaagg
    19381 tgattgagaa accggtcata tccagtgagg tgcagtacgc gccaattaaa ttacgttcga
    19441 tagtcaatcc cgcttgctgg caacgtgtgg tcaggcggtt atagacgccg tacagctcag
    19501 aaagcggagt tgcgccaaga ttgttaacca gcgcaatcac ccgatcgcca gactggagcg
    19561 gttgtttggt ttgttgttct tcctgccaac tgccttgttg ataatcccag aaacgcaaag
    19621 tgcgatggta tgagccattt tccagcaggg tgtcgaacat ttcatcgacg gtttgatcaa
    19681 gggaagagaa ggagcggcgg tcaatacccg gctcaccatg aatgccgacg ccaaactcca
    19741 tctcattatc cgccagggta aaagaaggtt tgcccgcggc aggaacggta caggcaccga
    19801 gagcgatacc tattgagtgg ccttgattat tcaacttacg ccccagttcc gcacaggcgt
    19861 ccagtgagtc gccacgctcc gccgctgcgc ctacgagttt ttcaattaat acggtgttgg
    19921 caacgccgcg tcgcccggcg gtataaagac tgtcttttac cgcaacgtcg tcatcaatga
    19981 ccacagtggt cacttttacg ccgctatcgt gcagtaactc ggtcgctgtt tcaaagttaa
    20041 gaatatcgcc ggtgtaattt ttgataatca acagtacacc ttcgccgcca tcaatttgca
    20101 tggagcattc aaagatttta tcgggcgtcg gtgaggtgaa aatttcgccc ggacaggccc
    20161 ccgaaagcat cccctgaccg atataaccac agtgcatcgg ctcgtgtccg ctgccgccac
    20221 ccgacagcag ggcgactttt cctgcaacag gggcatcagc tcgggtgaca tacaccggat
    20281 cctgatgcag tgtcagcgat ggatgcgctt tcgccagtcc tgccagttgt tcgtccagta
    20341 cgtcttgcac atcattgatc aattttttca ttattttgct ccagcaatta cggtagggca
    20401 tggatgatgt tcaacgacac ggcgaccact gactgccgat gaatccattg tgcatcaggc
    20461 aagggaaaag aaaattagcc caaattatgt ttcatagtga aacatatgct ttaatgaatg
    20521 ttccatattg aaacttttac gtgtattaat acttaaaatt gcgagccgga acaccttttg
    20581 tcataaggga tgcgggatat gagtggcgct tttaacaacg atggtcgggg catatctccc
    20641 ttaattgcaa cctcctggga gcgatgcaat aagctgatga aacgggagac atggaacgta
    20701 ccacatcagg cccagggcgt gacatttgct tctatttatc ggcgtaagaa agcgatgctg
    20761 acgctcgggc aggctgcgct ggaagatgcc tgggaatata tggcaccgcg agagtgtgcg
    20821 ctgtttatcc tcgatgaaac cgcctgcatt ctcagccgta atggcgatcc gcaaaccttg
    20881 cagcagctaa gtgcactggg attcaatgac ggcacgtatt gcgccgaggg aattattggt
    20941 acttgtgcac tatcgttagc ggctatctct ggtcaggccg tgaaaacgat ggccgatcaa
    21001 catttcaaac aggcactctg gaactgggcc ttttgtgcaa cgccgttgtt tgacagcaag
    21061 ggccgattga cgggaacaat agcgctggcg tgtccggttg agcaaactac cgcagctgat
    21121 ttgccgttga cgttagcaat cgcccgcgag gtcggtaatt tgctgctgac ggacagtttg
    21181 ctcgctgaaa ctaaccgtca tttaaatcaa cttaatgccc tgttagaaag tatggatgat
    21241 ggcgtgatta gctgggacga gcagggtaat ttgcaattta ttaatgccca ggcggcgcgg
    21301 gtcttgcgcc ttgacgcgac ggcaagtcag ggaagggcaa tcactgaact cttaacgtta
    21361 cccgccgtat tgcaacaagc aataaaacag gcacatccgc tcaaacacgt agaagcaacc
    21421 tttgaaagtc agcaccagtt tattgatgcg gtgataaccc ttaaaccgat aatagaaacg
    21481 cagggaacca gttttatttt gttgctccat cctgtggaac agatgcggca gttgatgacc
    21541 agtcaattag gaaaagtcag ccataccttc gctcatatgc cacaggacga tccgcaaacc
    21601 cgccgcttga ttcattttgg tcgccaggcg gcgcgcagta gctttcctgt cctgctttgt
    21661 ggagaagagg gcgtgggcaa ggcactgcta agtcaggcaa ttcataatga aagcgagcgt
    21721 gctgcaggtc cttatatcgc cgtcaattgt gagttatatg gtgatgcggc actggcggaa
    21781 gaatttattg gtggcgatcg cacggacaat gaaaatggcc gtctgagtcg gctggaactg
    21841 gcgcacggcg gcacgctgtt tcttgaaaag attgaatatc tggcggtgga gttacagtct
    21901 gctttgcttc aggttatcaa gcagggtgtt atcacgcgac tggatgcgcg gcgcttaata
    21961 ccaattgatg tcaaagtgat tgccacaacg accgcggacc tcgcaatgct ggtggaacaa
    22021 aatcgtttta gtcgccagct gtattacgcg ttgcatgcat ttgaaattac catcccgcct
    22081 ctgcgtatgc ggcgtggcag cattccggcg ctggtgaata acaaattacg cagtcttgaa
    22141 aaacgcttct ctacgcggct gaaaattgat gacgatgccc tcgctcgcct ggtttcctgt
    22201 gcatggcctg gcaacgattt tgaactttac agcgtcatcg agaatcttgc tctgagtagt
    22261 gataatgggc gcattcgcgt cagtgatttg ccggaacatc tgtttaccga gcaggcaaca
    22321 gatgatgtca gcgccacacg cctttccacc agtctgtcat ttgcggaagt tgaaaaagag
    22381 gcaattatta acgcagccca ggtcacaggc ggtcgcattc aggaaatgtc ggctttactt
    22441 gggatcggcc gcactacgct gtggcggaaa atgaagcaac atggcattga tgcagggcag
    22501 tttaagcgcc gggtatgaaa gacagagacg atttctgata catcagagtg atctatattt
    22561 cattccggcg cacgctaaca tttttcagca tcgtttaagg gctggtctat cccgcactta
    22621 aaagctgaag cgatatcctc cgttgacttg cttctgatca aagaggttac tctgcgtgta
    22681 atccgcttcg aggtagaatg tgtgctgttt gttatactgt gcactgactc ccacgccgtt
    22741 attccagcca ttacctttga aactgtactt ctcccgggag ttgttcaaca gatagtctgt
    22801 atcccctgaa aactcgcgga tagctccagt cttcacatac atattcagct ggctgttgcc
    22861 tgcggtgatg tcatatccca gtatcatgct ggcacgcccc agcagcgatt cgtagtgatt
    22921 cagatgtata ttgagaccat tactcgcctt catagccatc tcattctggt ggctgtatgt
    22981 gagctgggtt tgcggctcta tatagaaccc ataaccagta ggggtcaggt tgaacctctg
    23041 cccggcttcc agggagatgc tcaatccatt cgcagtgccg ttggcgttaa cgccgttgtt
    23101 ctgactgtcc agtacgtgaa aactattttt ctggcgcgat gcttttacaa cgagatcgct
    23161 gtaaaaaccg ttgtgtgcca tgtaactggc atacattccc atgtagtctg aacgtgcggt
    23221 accgtcgcct ccgctatagt ccggcgatgc atgtgttgag ccaatataca gaccgacata
    23281 caacggcatt acatcagaga gacgtttatc cccaccaaac tggataccgc tgtaacccat
    23341 gtcaaagccg ctcagtttgc cactggcgaa ggagtccagg cttcccccat aactgcgcag
    23401 ccagatatta ccgtctttac tctgatttcg caggtcaccc attcgttgca tcagcgtacg
    23461 gttttcaaca tagtttaata agtaaccgac attgagataa ttgccgccag catctgcggt
    23521 cgtggtgggt ttaggtgtgg gagtggggtt aggcgtagga tcgggttcag gcgtaggatc
    23581 ggggttgact atgggaggct gagcgggagc cggtgttggt tcaggattag gagtcggttc
    23641 cggaactgtc ccggaagcgt aaagctccca gttagtgcca tttttacgca catcgtacag
    23701 atatcccccc aactcaacct gagaagacgc gctgaacgag gccgcaccgt cagtggtttt
    23761 taccactgtc agaacttcat ttcccgtagt ggcctcgctg ccctggttgc ggatagccaa
    23821 tacgtgatta ccagcactac ttccgctgat attcaataaa tcccctttat tattaacgcc
    23881 attaccctcg ccaacaacat cagcacgcat aataaaggta ctgttaccgc tcaggttctc
    23941 tacgtttaat gtggcaaatg tgccggcagt tgacccgtgg ctggcaaaat cgacagttga
    24001 atggctcagc gccagcgtgt cgagattaga attacttgtt acgttccaga cgctgttatt
    24061 cattgcaacg tccagtttcc cgccattgac attatcgctg agggaggaac ctgtccaaac
    24121 cgaccctggg tgcatatcta gattgattag cccacctttg gaaagaacgc taccgttgat
    24181 aagcatacga cccgaggcgt tgatgcggct ggcggcataa ccatcgtcat gttgcgttgc
    24241 aatggccatc tggtcgggtg tactcatatc aatgaccaga tcgctcgtga ggtcgatctg
    24301 gctgttggtc atggcataaa ttcccctggc tcctgccgcg ccggtgatag ccaaactgtc
    24361 tccggttatt ctaccgccgc tgagcgccca caaacccagc gccagactgc cattacgatc
    24421 aactgtaata tcggtatttt gcatgttgac aacagccgtt gccgtctggg ccgaggcacc
    24481 ataagaaccg ccggaaaaga tgctgtttcg ttgcgctgcc gtgccagaaa aattgattgt
    24541 cgcgtctgaa ccactggtga cgaggccacc gccctgcgcg gaagaaatat ggctatctgc
    24601 accgatagtg gttgtaccac cacgaacttc gacgccattg gccgcggctc cagttacatc
    24661 aacagtgagt gcattcgcgc taacctggcc aaagctccag aggccgtgtg cattatcgcc
    24721 attggtttta atggtactgt ttgttccgag atcgacaaca gagtttttct gtacgtttat
    24781 ccccatggcg ctgtagccct gaacatcgat tgtcaggtct gtcgccgtaa aacgcgcagc
    24841 accattggcg ttattgccgt tgagaccacc gatataaaca cctgtacttc catcggtcgt
    24901 gattttactt ccgcttccaa gatcgacact ggtgccatag tcattgatgg ttaggcctat
    24961 accgttcgag ttttcaatgg tgaattgagt ggctgttagt gttgagctat gcccaataat
    25021 gatgccgtca tcgttactct taatggtgct gcctgtgcct aagtcagcat gggtatagtc
    25081 accaattaag ttaatgccga tggcagaggt ttgaccaaca acatctactg tgagtcggtt
    25141 agctgtcagg gagctgtttt tgccctgaat aatgattcct tttgcatatc cagaggcgtc
    25201 gttgacattg acggtgacat cattacccag gttgatattg ccaggcgtgt ttcctgctgg
    25261 ggtcattaca ccatagaggt ttcctgatgg atcggcggta tctcctgtaa ttctgtcacc
    25321 atcattaata gtaatattgg tgccatattg acttcctgta tcagcagcta tcagcagggg
    25381 ggaaaagata attgcattca aaccaatagc gccaaatttt atcagttgac ttgagggcga
    25441 acggattttt aattcagcga gacgatctgc tttggtattc ccattgtgtt gtttgatgcc
    25501 cataccactc ctatatagta cccagactat gggtctatgg attttgtcat tttgtttaaa
    25561 tcaatgaata atatcctctt atcatcatga tatttgtatg gtgcaatcat gatgagcttc
    25621 tcagagaata attctctatt accgggcaaa atcaggaaca caggaattaa tatatattta
    25681 acatccccct tacaaaggtg ggtttatatc gagttattcc ctaagttgtc gttg
//
LOCUS       DAPGUL010000060        25245 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.060, whole genome shotgun sequence.
ACCESSION   DAPGUL010000060 DAPGUL010000000
VERSION     DAPGUL010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25245
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.060"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..1136
                     /locus_tag="RHX21_002696"
     CDS             <1..1136
                     /locus_tag="RHX21_002696"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HDV1987857.1"
                     /translation="YPQSAAIDLRCVNMVADLWHAPAPKNGQAVGTNTIGSSEACMLG
                     GMAMKWRWRKRMEAAGKPTDKPNLVCGPVQICWHKFARYWDVELREIPMRPGQLFMDP
                     KRMIEACDENTIGVVPTFGVTYTGNYEFPQPLHDALDKFQADTGIDIDMHIDAASGGF
                     LAPFVAPDIVWDFRLPRVKSISASGHKFGLAPLGCGWVIWRDEEALPQELVFNVDYLG
                     GQIGTFAINFSRPAGQVIAQYYEFLRLGREGYTKVQNASYQVAAYLADEIAKLGPYEF
                     ICTGRPDEGIPAVCFKLKDGEDPGYTLYDLSERLRLRGWQVPAFTLGGEATDIVVMRI
                     MCRRGFEMDFAELLLEDYKASLKYLSDHPKLQGIAQQNSFKHT"
     gene            1292..2827
                     /gene="gadC"
                     /locus_tag="RHX21_002697"
     CDS             1292..2827
                     /gene="gadC"
                     /locus_tag="RHX21_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance gamma-aminobutyrate antiporter
                     GadC"
                     /protein_id="HDV1987858.1"
                     /translation="MATSVQTGKAKQLTLLGFFAITASMVMAVYEYPTFATSGFSLVF
                     FLLLGGILWFIPVGLCAAEMATVDGWEEGGVFAWVSNTLGPRWGFAAISFGYLQIAIG
                     FIPMLYFVLGALSYILKWPALNEDPITKTIAALIILWALALTQFGGTKYTARIAKVGF
                     FAGILLPAFILIALAAIYLHSGAPVAIEMDSKTFFPDFSKVGTLVVFVAFILSYMGVE
                     ASATHVNEMSNPGRDYPLAMLLLMVAAICLSSVGGLSIAMVIPGNEINLSAGVMQTFT
                     VLMSHVAPEIEWTVRVISALLLLGVLAEIASWIVGPSRGMYVTAQKNLLPAAFAKMNK
                     NGVPVTLVISQLVITSIALIILTNTGGGNNMSFLIALALTVVIYLCAYFMLFIGYIVL
                     VLKHPDLKRTFNIPGGKGVKLVVAIVGLLTSIMAFIVSFLPPDNIQGDSTDMYVELLV
                     VSFLVVLALPFILYAVHDRKGKANTGVTLEPINSQNAPKGHFFLHPRARSPHYIVMND
                     KKH"
     gene            2958..4277
                     /locus_tag="RHX21_002698"
     CDS             2958..4277
                     /locus_tag="RHX21_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 10 protein"
                     /protein_id="HDV1987859.1"
                     /translation="MDICSRNKKLTIRRPAILVALALLLCSCKSTPPESMVTPPAGSK
                     PPATTQQSSQPMRGIWLATVSRLDWPPVSSVNISNPTSRARVQQQAMIDKLNHLQRLG
                     INTVFFQVKPDGTALWPSKILPWSDLMTGKIGENPGYDPLQFMLDEAHKRGMKVHAWF
                     NPYRVSVNTKPGTIRELNSTLSQQPASVYVQHRDWIRTSGDRFVLDPGIPEVQDWITS
                     IVAEVVSRYPVDGVQFDDYFYTESPGSRLNDNETYRKYGGAFASKADWRRNNTQQLIA
                     KVSHTIKSIKPGVEFGVSPAGVWRNRSHDPLGSDTRGAAAYDESYADTRRWVEQGLLD
                     YIAPQIYWPFSRSAARYDVLAKWWADVVKPTRTRLYIGIAFYKVGEPSKIEPDWMING
                     GVPELKKQLDLNDAVPEISGTILFREDYLNKPQTQQAVSYLQSRWGS"
     gene            4649..6031
                     /gene="dosC"
                     /locus_tag="RHX21_002699"
     CDS             4649..6031
                     /gene="dosC"
                     /locus_tag="RHX21_002699"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DosC"
                     /protein_id="HDV1987860.1"
                     /translation="MEMYFKRMKDEWTGLVEQADPLIRAKAAEIALAHAHYLSIEFYR
                     IVRIDPHAEEFLSNEQVERQLKSAMERWIINVLSAQVDDVERLIQIQHTVAEVHARIG
                     IPVEIVEMGFRVLKKILYPVIFSSDYSAAEKLQVYHFSINSIDIAMEVMTRAFTFSDS
                     SASKEDENYRIFSLLENAEEEKERQIASILSWEIDIIYKILLDSDLGSSLPLSQADFG
                     LWFNHKGRHYFSGIAEVGHISRLIQDFDGIFNQTMRNTRNLNNRSLRVKFLLQIRNTV
                     SQIITLLRELFEEVSRHEVGMDVLTKLLNRRFLPTIFKREIAHANRTGTPLSVLIIDV
                     DKFKEINDTWGHNTGDEILRKVSQAFYDNVRSSDYVFRYGGDEFIIILTEASENETLR
                     TAERIRSRVEKTKLKAANGEDIALSLSIGAAMFNGHPDYERLIQIADEALYIAKRRGR
                     NRVELWKASL"
     gene            6056..8455
                     /gene="dosP"
                     /locus_tag="RHX21_002700"
                     /gene_synonym="pdeO"
     CDS             6056..8455
                     /gene="dosP"
                     /locus_tag="RHX21_002700"
                     /gene_synonym="pdeO"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416006.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-sensing cyclic-di-GMP phosphodiesterase"
                     /protein_id="HDV1987861.1"
                     /translation="MKLTDADNAADGIFFPALEQNMMGAVLINENDEVMFFNPAAEKL
                     WGYKREEVIGNNIDMLIPRDLRPAHPEYIRHNREGGKARVEGMSRELQLEKKDGSKIW
                     TRFALSKVSAEGKVYYLALVRDASVEMAQKEQTRQLIIAVDHLDRPVIVLDPERHIVQ
                     CNRAFTEMFGYCISEASGMQPDTLLNIPEFPADNRIRLQQLLWKTARDQDEFLLLTRT
                     GEKIWIKASISPVYDVLAHLQNLVMTFSDITEERQIRQLEGNILAAMCSSPPFHEMGE
                     IICRNIESVLNESHVSLFALRNGMPIHWASSSHGAEVQNAQSWSATIRQRDGAPAGIL
                     QIKTSSGAETSAFIERVADISQHMAALALEQEKSRQHIEQLIQFDPMTGLPNRNNLHN
                     YLDDLVDKAVSPVVYLIGVDHIQDVIDSLGYAWADQALLEVVNRFREKLKPDQYLCRI
                     EGTQFVLVSLENDVSNITQIADELRNVVSKPIMIDDKPFPLTLSIGISYDVGKNRDYL
                     LSTAHNAMDYIRKNGGNGWQFFSPAMNEMVKERLVLGAALKEAISNNQLKLVYQPQIF
                     AETGELYGIEALARWHDPQHGHVPPSRFIPLAEEIGEIENIGRWVIAEACRQLAEWRS
                     QNIHIPALSVNLSALHFRSNQLPNQVSDAMHAWGIDGHQLTVEITESMMMEHDTEIFK
                     RIQILRDMGVGLSVDDFGTGFSGLSRLVSLPVTEIKIDKSFVDRCLTEKRILALLEAI
                     TSIGQSLNLTVVAEGVETKEQFEMLRKIHCRVIQGYFFSRPLPAEEIPGWMSSVLPLK
                     I"
     gene            8713..9294
                     /gene="ddpX"
                     /locus_tag="RHX21_002701"
     CDS             8713..9294
                     /gene="ddpX"
                     /locus_tag="RHX21_002701"
                     /EC_number="3.4.13.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine dipeptidase"
                     /protein_id="HDV1987862.1"
                     /translation="MSDTTELVDLAVIFPDLEIELKYACADNITGKAIYQQARCLLHK
                     DAITALAKSISIAQLSGLQLVIYDAYRPQQAQAMLWQACPDPQYVVDVTVGSNHSRGT
                     AIDLTLRDEHGNILDMGAGFDEMHERSHAYHPSVPPAAQRNRLLLNAIMTGGGFVGIS
                     SEWWHFELPQAASYPLLADQFTCFISPGTQHVS"
     gene            9308..10858
                     /locus_tag="RHX21_002702"
     CDS             9308..10858
                     /locus_tag="RHX21_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDV1987863.1"
                     /translation="MKRSIPFRPTLLALVLATNFPVAHAAVPKDMLVIGKAADPQTLD
                     PAVTIDNNDWTVTYPSYQRLVQYKTDGDKGSTDVEGDLASSWKASDDQKEWTFTLKDN
                     AKFADGTPVTAEAVKLSFERLLKIGQGPAEAFPKDLKIDAPDEHTVKFTLSQPFAPFL
                     YTLANDGASIINPAVLKEHAADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYP
                     GNKPNFKRVSVKIIGESASRRLQLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLR
                     VTYLYLNNSKAPLNQADLRRAISWSTDYQGMVNGILSGNGKQMRGPIPEGMWGYDATA
                     MQYNHDETKAKAEWDKVTSKPTSLTFLYSDNDPNWEPIALATQSSLNKLGINVKLEKL
                     ANATMRDRVGKGDYDIAIGNWSPDFADPYMFMNYWFESDKKGLPGNRSFYENSEVDKL
                     LRNALATTDQTQRTRDYQQAQKIVIDDAAYVYLFQKNYQLAMNKEVKGFVFNPMLEQV
                     FNINTMSK"
     gene            10860..11882
                     /locus_tag="RHX21_002703"
     CDS             10860..11882
                     /locus_tag="RHX21_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV1987864.1"
                     /translation="MTFWSILRQRCWGLVLVVAGVCVITFIISHLIPGDPARLLAGDR
                     ASDAIVENIRQQLGLDQPLYVQFYRYVSDLFHGDLGTSIRTGRPVLEELRIFFPATLE
                     LAFCALLLALLIGIPLGILSAVWRNRWLDHLVRIMAITGISTPAFWLGLGVIVLFYGH
                     LQILPGGGRLDDWLDPPTHVTGFYLLDALLEGNGEVFFNALQHLILPALTLAFVHLGI
                     VARQIRSAMLEQLSEDYIRTARASGLPGWYIVLCYALPNALIPSITVLGLALGDLLYG
                     AVLTETVFAWPGMGAWVVTSIQALDFPAVMGFAVVVSFAYVLVNLVVDLLYLWIDPRI
                     GRGGGE"
     gene            11879..12775
                     /locus_tag="RHX21_002704"
     CDS             11879..12775
                     /locus_tag="RHX21_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D,D-dipeptide ABC transporter permease"
                     /protein_id="HDV1987865.1"
                     /translation="MMLSEETSAVRPQKQTRFNGAKLVWMLKGSPLTVTGAVIIVLML
                     LMMIFSPWLATHDPNAIDLTARLLPPSAAHWFGTDEVGRDLFSRVLVGSQQSILAGLV
                     VVAIAGMIGSLLGCLSGVLGGRADAIIMRIMDIMLSIPSLVLTMALAAALGPSLFNAM
                     LAIAIVRIPFYVRLARGQALVVRQYTYVQAAKTFGASRWHLINWHILRNSLPPLIVQA
                     SLDIGSAILMAATLGFIGLGAQQPSAEWGAMVANGRNYVLDQWWYCAFPGAAILLTAV
                     GFNLFGDGIRDLLDPKAGGKQS"
     gene            12772..13758
                     /locus_tag="RHX21_002705"
     CDS             12772..13758
                     /locus_tag="RHX21_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDV1987866.1"
                     /translation="MTQPVLDIQQLHLSFPGFNGDVHALNNVSLQINRGEIVGLVGES
                     GSGKSVTAMLIMRLLQTGSYCVHRGQISLLGDDVLNAREKQLRQWRGARVAMIFQEPM
                     TALNPTLRIGLQMMDVIRHHQPISRREARAKAIALLEEMQIPDAVEVMSRYPFELSGG
                     MRQRVMIALAFSCEPQLIIADEPTTALDVTVQLQVLRLLKHKARASGTAVLFISHDMA
                     VVSQLCDSVYVMYAGSVIESGVTADVIHHPRHPYTIGLLQCAPEHGVPRQLLPAIPGT
                     VPNLTHLPEGCAFRDRCYAAGAQCENVPALTACGDNNQRCACWYPQQEVISV"
     gene            13751..14677
                     /locus_tag="RHX21_002706"
     CDS             13751..14677
                     /locus_tag="RHX21_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDV1987867.1"
                     /translation="MSDTLLTLRDVHINFPARKNWLGKTTEHVHAINGIDLQIRRGET
                     LGIVGESGCGKSTLAQLLMGMLQPSHGQYIRSGSQRIMQMVFQDPLSSLNPRLPVWRI
                     ITEPLWIAKRSSEQQRRALAEELAVQVGIRPEYLDRLPHAFSGGQRQRIAIARALSSQ
                     PDVIVLDEPTSALDISVQAQILNLLVTLQVNRGLTYVLISHNVSVIRHMSDRVAVMYL
                     GQIVELGDAQQVLTAPAHPYTRLLLDSLPAIDKPLEEEWALRKTDLPGNRTLPQGCFF
                     YERCPLATHGCEVRQSLTIREDGREIRCWRAL"
     gene            complement(14733..15164)
                     /gene="osmC"
                     /locus_tag="RHX21_002707"
     CDS             complement(14733..15164)
                     /gene="osmC"
                     /locus_tag="RHX21_002707"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin OsmC"
                     /protein_id="HDV1987868.1"
                     /translation="MTIHKKGQAHWEGDIKRGKGTVSTESGVLNQQPYGFNTRFEGEK
                     GTNPEELIGAAHAACFSMALSLMLGEAGFTPTSIDTTADVSLDKVDAGFAITKIALKS
                     EVAVPGIDASTFDGIIQKAKAGCPVSQVLKAEITLDYQLKS"
     gene            15510..15725
                     /gene="bdm"
                     /locus_tag="RHX21_002708"
     CDS             15510..15725
                     /gene="bdm"
                     /locus_tag="RHX21_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310112.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-dependent modulation protein"
                     /protein_id="HDV1987869.1"
                     /translation="MFTYYQAENSTAEPALVNAIEQGLRAEHGVVTEDDILMELTKWV
                     EASDNDILSDIYQQTINYVVSGQHPTL"
     gene            15827..15964
                     /gene="sra"
                     /locus_tag="RHX21_002709"
     CDS             15827..15964
                     /gene="sra"
                     /locus_tag="RHX21_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stationary-phase-induced ribosome-associated
                     protein"
                     /protein_id="HDV1987870.1"
                     /translation="MKSNRQARHILGLDHKISNQRKIVTEGDKSSVVNNPTGRKRPAE
                     K"
     gene            16121..17818
                     /gene="maeA"
                     /locus_tag="RHX21_002710"
     CDS             16121..17818
                     /gene="maeA"
                     /locus_tag="RHX21_002710"
                     /EC_number="1.1.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707611.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase"
                     /protein_id="HDV1987871.1"
                     /translation="MEPKTKKQRSLYIPYAGPVLLEFPLLNKGSAFSMEERRNFNLLG
                     LLPEVVETIEEQAERAWIQYQGFKTEIDKHIYLRNIQDTNETLFYRLVNNHLDEMMPV
                     IYTPTVGAACERFSEIYRRSRGVFISYQNRHNMDDILQNVPNHNIKVIVVTDGERILG
                     LGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNQQLLNDPLYMGWRNPRI
                     TDDEYYEFVDEFIQAVKQRWPDVLLQFEDFAQKNAMPLLNRYRNEICSFNDDIQGTAA
                     VTVGTLIAASRAAGGQLSEKKIVFLGAGSAGCGIAEMIISQTQREGLSEEAARQKVFM
                     VDRFGLLTDKMPNLLPFQTKLVQKRENLSDWDTDSDVLSLLDVVRNVKPDILIGVSGQ
                     TGLFTEEIIREMHKHCPRPIVMPLSNPTSRVEATPQDIIAWTEGNALVATGSPFNPVV
                     WKDKIYPIAQCNNAFIFPGIGLGVIASGASRITDEMLMSASETLAQYSPLVLNGEGLV
                     LPELKDIQKVSRAIAFAVGKMAQQQGVAVKTSAEALQQAIDDNFWQAEYRDYRRTSI"
     gene            17952..18962
                     /gene="adhP"
                     /locus_tag="RHX21_002711"
     CDS             17952..18962
                     /gene="adhP"
                     /locus_tag="RHX21_002711"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310109.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HDV1987872.1"
                     /translation="MKAAVVTKDHHVDVTDKTLRSLKHGEALLKMECCGVCHTDLHVK
                     NGDFGDKTGVILGHEGIGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNSGNETL
                     CRSVKNAGYSVDGGMAEECIVVADYAVKVPDGLDSAAASSITCAGVTTYKAVKLSKIR
                     PGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINSRTEDA
                     AKIVQEKTGGAHAAVVTAVAKAAFNSAVDAVRAGGRVVAVGLPPESMSLDIPRLVLDG
                     IEVVGSLVGTRQDLTEAFQFAAEGKVVPKVALRPLADINTIFTEMEEGKIRGRMVIDF
                     RR"
     gene            19109..19393
                     /locus_tag="RHX21_002712"
     CDS             19109..19393
                     /locus_tag="RHX21_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415994.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HigA family addiction module antidote protein"
                     /protein_id="HDV1987873.1"
                     /translation="MKMANHPRPGDIIQESLDELNVSLREFARAMEIAPSTASRLLTG
                     KAALTPEMAIKLSVVIGSSPQMWLNLQNAWSLAEAEKTVDVSRLRRLVTQ"
     gene            complement(19444..20097)
                     /gene="fdnI"
                     /locus_tag="RHX21_002713"
     CDS             complement(19444..20097)
                     /gene="fdnI"
                     /locus_tag="RHX21_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit gamma"
                     /protein_id="HDV1987874.1"
                     /translation="MSKSKMIVRTKFIDRACHWTVVICFFLVALSGISFFFPTLQWLT
                     QTFGTPQMGRILHPFFGIAIFVALMFMFVRFVHHNIPDKKDIPWLLNIVEVLKGNEHK
                     VADVGKYNAGQKMMFWSIMSMIFVLLVTGVIIWRPYFAQYFPMQVVRYSLLIHAAAGI
                     ILIHAILIHMYMAFWVKGSIKGMIEGKVSRRWAKKHHPRWYREIEKAEAKKESEEGI"
     gene            complement(20090..20974)
                     /gene="fdnH"
                     /locus_tag="RHX21_002714"
     CDS             complement(20090..20974)
                     /gene="fdnH"
                     /locus_tag="RHX21_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase N subunit beta"
                     /protein_id="HDV1987875.1"
                     /translation="MAMETQDIIKRSATNSITPPSQVRDYKAEVAKLIDVSTCIGCKA
                     CQVACSEWNDIRDEVGHCVGVYDNPADLSAKSWTVMRFSETEQNGKLEWLIRKDGCMH
                     CEDPGCLKACPSAGAIIQYANGIVDFQSENCIGCGYCIAGCPFNIPRLNKEDNRVYKC
                     TLCVDRVSVGQEPACVKTCPTGAIHFGTKKEMLELAEQRVAKLKARGYEHAGVYNPEG
                     VGGTHVMYVLHHADQPELYHGLPKDPKIDTSVSLWKGALKPLAAAGFIATFAGLIFHY
                     IGIGPNKEVDDDEEDHHE"
     gene            complement(20987..24034)
                     /gene="fdnG"
                     /locus_tag="RHX21_002715"
     CDS             complement(20987..24034)
                     /gene="fdnG"
                     /locus_tag="RHX21_002715"
                     /EC_number="1.17.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(23447..23449),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit alpha"
                     /protein_id="HDV1987876.1"
                     /translation="MDVSRRQFFKICAGGMAGTTVAALGFAPKQALAQARNYKLLRAK
                     EIRNTCTYCSVGCGLLMYSLGDGAKNAREAIYHIEGDPDHPVSRGALCPKGAGLLDYV
                     NSENRLRYPEYRAPGSDKWQRISWEEAFSRIAKLMKADRDANFIEKNEQGVTVNRWLS
                     TGMLCASGASNETGMLTQKFARSLGMLAVDNQARVUHGPTVASLAPTFGRGAMTNHWV
                     DIKNANVVMVMGGNAAEAHPVGFRWAMEAKNNNDATLIVVDPRFTRTASVADIYAPIR
                     SGTDITFLSGVLRYLIENDKINAEYVKHYTNASLLVRDDFAFEDGLFSGYDAEKRQYD
                     KSSWNYQFDENGYAKRDETLTHPRCVWNLLKAHVSRYTPDVVENICGTPKADFLKVCE
                     VLASTSAPDRTTTFLYALGWTQHTVGAQNIRTMAMIQLLLGNMGMAGGGVNALRGHSN
                     IQGLTDLGLLSTSLPGYLTLPSEKQVDLQSYLEANTPKATLADQVNYWSNYPKFFVSL
                     MKSFYGDAAQKENNWGYDWLPKWDQTYDVIKYFNMMDEGKVTGYFCQGFNPVASFPDK
                     NKVVSCLSKLKYMVVIDPLVTETSTFWQNHGESNDVDPASIQTEVFRLPSTCFAEEDG
                     SIANSGRWLQWHWKGQDAPGEARNDGEILAGIYHHLRELYQAEGGKGVEPLMKMSWNY
                     KQPHEPQSDEVAKENNGYALEDLYDANGVLIAKKGQLLSSFAHLRDDGTTASSCWIYT
                     GSWTEQGNQMANRDNSDPSGLGNTLGWAWAWPLNRRVLYNRASADINGKPWDPKRMLI
                     QWNGSKWTGNDIPDFGNAAPGTPTGPFIMQPEGMGRLFAINKMAEGPFPEHYEPIETP
                     LGTNPLHPNVVSNPVVRLYEQDALRMGKKEQFPYVGTTYRLTEHFHTWTKHALLNAIA
                     QPEQFVEISETLAAAKGINNGDRVTVSSKRGFIRAVAVVTRRLKPLNVNGQQVETVGI
                     PIHWGFEGVARKGYIANTLTPNVGDANSQTPEYKAFLVNIEKA"
     gene            24266..25147
                     /gene="yddG"
                     /locus_tag="RHX21_002716"
     CDS             24266..25147
                     /gene="yddG"
                     /locus_tag="RHX21_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415990.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid efflux DMT transporter YddG"
                     /protein_id="HDV1987877.1"
                     /translation="MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGATAIYSLS
                     GLLLIFTVGFPRIRQIPKGYLLAGSLLFVSYEICLALSLGYAATRHQAIEVGMVNYLW
                     PSLTILFAILFNGQKTNWLIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYF
                     LAFIGAFIWAAYCTVTNKYARGFNGITVFVLLTGASLWVYYFLTPQPEMVFSTPVMIK
                     LISAAFTLGFAYAAWNVGILHGNVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGA
                     LMVCGGSLLCWLATRRG"
BASE COUNT         6140 a         6434 c         6407 g         6264 t
ORIGIN      
        1 aatatccgca atccgcagcc atcgacctac gttgcgtaaa tatggttgcc gatctgtggc
       61 atgcgcctgc gccgaaaaat ggtcaggccg ttggcaccaa caccattggt tcttccgagg
      121 cctgtatgct cggcgggatg gcgatgaaat ggcgttggcg caagcgtatg gaagctgcag
      181 gcaaaccaac ggataaacca aacctggtgt gcggtccggt acaaatctgc tggcataaat
      241 tcgcccgcta ctgggatgtg gagctgcgtg agatccctat gcgccccggt cagttgttta
      301 tggacccgaa acgcatgatt gaagcctgtg acgaaaacac catcggcgtg gtgccgactt
      361 tcggcgtgac ctacactggt aactatgagt tcccacaacc gctgcacgat gcgctggata
      421 aattccaggc cgataccggt atcgacatcg acatgcacat cgacgctgcc agcggtggct
      481 tcctggcacc gttcgtcgcc ccggatatcg tctgggactt ccgcctgccg cgtgtgaaat
      541 cgatcagtgc ttcaggccat aaattcggtc tggctccgct gggctgcggc tgggttatct
      601 ggcgtgacga agaagcgctg ccgcaggaac tggtgttcaa cgttgactac ctgggtggtc
      661 aaattggtac tttcgccatc aacttctccc gcccggcggg tcaggtaatt gcacagtact
      721 atgaattcct gcgcctcggt cgtgaaggct acaccaaagt acagaacgcc tcttaccagg
      781 ttgccgctta tctggcggat gaaatcgcca aactggggcc gtatgagttc atctgtacgg
      841 gtcgcccgga cgaaggcatc ccggcggttt gcttcaaact gaaagatggt gaagatccgg
      901 gatacaccct gtacgacctc tctgaacgtc tgcgtctgcg cggctggcag gttccggcct
      961 tcactctcgg cggtgaagcc accgacatcg tggtgatgcg cattatgtgt cgtcgcggct
     1021 tcgaaatgga ctttgctgaa ctgttgctgg aagactacaa agcctccctg aaatatctca
     1081 gcgatcaccc gaaactgcag ggtattgccc agcagaacag ctttaaacat acctgataac
     1141 gtttaacggt aacggtgtcc cgaaacgaac ccgtttcggg acaatttcca aagtctgttc
     1201 actggcatta gcaacggaaa atattgttct gaatacgctt cagaacaaaa caggtgcggt
     1261 tccgacagga ataccgtttt agggggataa tatggctaca tcagtacaga caggtaaagc
     1321 taagcagctc acattactcg gattctttgc cataacggca tcgatggtaa tggctgttta
     1381 tgaataccct accttcgcaa catcgggctt ttcattagtc ttcttcctgc tattaggcgg
     1441 gattttatgg tttattcccg tgggactttg tgctgcggaa atggccaccg tcgacggctg
     1501 ggaagaaggt ggtgtcttcg cctgggtatc aaatactctg gggccgagat ggggatttgc
     1561 agcgatctca tttggctatc tgcaaatcgc cattggtttt attccgatgc tctatttcgt
     1621 gttaggggca ctctcctaca tcctgaaatg gccagcgctg aatgaagacc ccattaccaa
     1681 aactattgca gcactcatca ttctttgggc gctggcatta acgcagtttg gtggcacgaa
     1741 atacacggcg cgaattgcta aagttggctt cttcgccggt atcctgttac ctgcatttat
     1801 tttgatcgca ttagcggcta tttatctgca ctccggtgcc cccgttgcta tcgaaatgga
     1861 ttcgaagacc ttcttccctg acttctctaa agtgggcaca ctggttgtat ttgttgcctt
     1921 cattttgagt tatatgggcg tagaagcttc cgcaactcac gtcaatgaaa tgagcaaccc
     1981 cgggcgcgac tatccactgg ctatgttact gctgatggtg gcggcaatct gcttaagctc
     2041 tgttggcggt ttgtctattg cgatggtcat tccgggtaat gaaatcaacc tctccgcagg
     2101 tgtaatgcaa acctttaccg ttctgatgtc ccatgtggca ccggaaattg agtggacggt
     2161 tcgcgtgatc tccgcactgc tgttgctggg tgttttggcg gaaatcgcct cctggattgt
     2221 tggtccttct cgcgggatgt atgtcacagc gcagaaaaac ctgctgccag cggcattcgc
     2281 taaaatgaac aaaaatggcg taccggtaac gctggtcatt tcgcagctgg tgattacttc
     2341 tatcgcgttg atcatcctca ccaataccgg tggcggtaac aacatgtcct tcctgatcgc
     2401 tctggcgctg acggtggtga tttatctgtg tgcttatttc atgctgttta ttggctacat
     2461 tgtgttggtt cttaaacatc ctgacttaaa acgcacattt aatatccctg gtggtaaagg
     2521 ggtgaaactg gtcgtggcaa ttgtcggtct gctgacttca attatggcgt ttattgtttc
     2581 cttcctgccg ccggataaca tccagggtga ttctaccgat atgtatgttg aattactggt
     2641 tgttagtttc ctggtggtac ttgccctgcc ctttattctc tatgctgttc atgatcgtaa
     2701 aggcaaagcg aataccggcg tcactctgga gccaatcaac agtcagaacg caccaaaagg
     2761 tcacttcttc ctgcacccgc gtgcacgttc accacactat attgtgatga atgacaagaa
     2821 acactaacca tgtctgaatg gttataagac aagggagcga taagtcatcg ctcccttttt
     2881 cgtgcttgct gtcgtattga cttaaccggg ataagtacga gaatgagcgc acatctgttt
     2941 accggaaacc agcacatatg gatatctgct cccgaaacaa gaaattaacg attagaagac
     3001 cagcgatact agttgcactg gcacttttac tgtgtagttg taaaagcacg cctccagagt
     3061 ccatggtgac accaccagca ggttcaaagc caccagccac gacgcaacaa tcgtcacaac
     3121 cgatgcgtgg catctggctg gccacggttt ctcgcctcga ctggccaccg gtttcctcgg
     3181 ttaacattag taaccccacc agccgggccc gtgtacaaca acaggcgatg atcgacaaac
     3241 tgaatcatct gcaacgtctc ggtataaaca cggttttttt ccaggtcaag ccggacggta
     3301 ccgccctgtg gccatcgaaa attttgccgt ggtccgatct tatgaccggt aagattggtg
     3361 aaaatccggg ttacgatccg ctgcaattta tgctcgacga agcccacaag cgtgggatga
     3421 aagtacacgc ctggtttaac ccctatcgcg tatcggttaa tacgaagccc ggtactatca
     3481 gggaactgaa tagcactctg tctcaacaac cggcgagcgt ctatgtgcaa caccgtgact
     3541 ggatcagaac gtctggcgat cgctttgtcc tcgacccggg catccctgag gttcaggact
     3601 ggatcacatc aatagtcgca gaagtggttt cccgctatcc ggtagatggc gtgcagtttg
     3661 acgactattt ctatacggag tcaccgggtt cacggctaaa tgataacgaa acgtaccgca
     3721 aatacggagg cgcatttgcg tcaaaagcag actggcggcg caacaatact cagcagttaa
     3781 ttgcaaaagt atcgcacacc attaaaagca ttaagccggg agtcgaattt ggcgttagcc
     3841 cggcaggcgt gtggcgtaac cgatcacacg atccgctcgg ttccgatacc cgaggtgcgg
     3901 cagcctatga cgaatcctac gctgacaccc gtcgatgggt ggaacaagga ttgctggatt
     3961 atattgctcc ccaaatttac tggccgttct cacggagtgc cgcgcgttat gacgtgttgg
     4021 caaaatggtg ggcggatgtc gttaaaccga ccaggacccg cctgtatatc ggtatcgcct
     4081 tctataaagt gggtgaacct tcaaagatag agccagactg gatgattaac ggcggcgtac
     4141 ccgaactgaa aaagcagctc gatcttaacg atgcggtacc cgaaattagc ggcaccatct
     4201 tgttccgtga ggactatctg aataaaccgc agactcaaca agcggtcagc tatctgcaaa
     4261 gtcgttgggg cagttaaact cccattctta ctttgtaaca agccggtgct ttacccaccg
     4321 gcttgttacc ctcttgaact atcccactac taatcatgct tactaaagtc aaattaacca
     4381 cgcaattaac cacacttagt taaacagcca taaatcccct aataaaaatg tatgaatatg
     4441 aaaaaacata cgatattcgc tgtcaccgaa aaataattac gatgggctat actcttctga
     4501 agaacagtag cgtagattaa aactgtccta agtcgcttat ttcttttcag tatatcttca
     4561 tatttcagga gaatatggtg cagttagtcg atctcgcacg ttgcgttttg attccgtctg
     4621 atttcccagc cttataaggg tgtgaattat ggagatgtat tttaaaagaa tgaaagatga
     4681 gtggaccgga cttgtcgaac aggcagatcc tctcattcgt gctaaagccg cagaaattgc
     4741 ccttgcgcat gctcattatc tgagtatcga gttttatcga attgtccgca tcgacccgca
     4801 tgccgaagaa ttcttgagta atgaacaagt tgagcggcag ttgaaaagtg cgatggaacg
     4861 ctggattatt aacgtgcttt ctgcccaggt tgacgatgtc gaaaggctaa tacaaatcca
     4921 gcataccgtc gcggaagtgc atgcccgcat tggaattccg gtagaaattg tcgagatggg
     4981 gtttcgggtg ctgaaaaaaa tcctctatcc ggtaatcttc tcttcggatt attctgccgc
     5041 agaaaaactt caggtctacc atttctcgat taacagtatt gatatcgcta tggaagtgat
     5101 gacccgcgcg tttaccttta gtgacagtag tgcctcaaag gaagatgaaa actatcgtat
     5161 cttctcgtta ctggaaaacg ccgaagaaga aaaagaacgg caaatagcct caatactttc
     5221 atgggaaata gatattatct ataaaatcct gctggattct gatttaggca gtagtttgcc
     5281 tttaagccag gctgattttg gcctgtggtt taaccataaa ggtcgacatt attttagcgg
     5341 cattgccgaa gtaggccata tctcccgtct gattcaggat ttcgacggta ttttcaatca
     5401 aaccatgcgt aacaccagga atttgaataa cagaagtttg cgggtgaagt ttctattaca
     5461 gataagaaat accgtatcgc aaattattac cttgctgcgt gaattgtttg aagaagtatc
     5521 gcgccacgaa gtcggtatgg atgtactgac gaaattactt aaccgccgtt tcctgccgac
     5581 tatcttcaaa cgcgaaattg cccatgccaa ccggaccggt acaccgctgt cagtgctgat
     5641 tattgacgtt gataaattca aagagatcaa cgatacgtgg ggccataaca ctggcgatga
     5701 aattctgcgt aaagtctctc aggcctttta tgacaacgtc cgcagtagtg attatgtttt
     5761 ccgctacggg ggcgatgaat ttatcattat tttgactgaa gcttctgaaa acgaaacgtt
     5821 acgtaccgca gaacgtattc gcagtcgggt ggagaaaacc aaactgaaag ccgcaaacgg
     5881 cgaggatatt gccctctcac tttccatcgg tgccgccatg tttaatggtc atcctgacta
     5941 tgagcgcctc attcaaatag ccgatgaagc tctgtatatc gccaaaagac gaggtagaaa
     6001 ccgtgttgaa ctctggaaag ccagtcttta gatgcgccag gatgcagagg taatcatgaa
     6061 gctaaccgat gcggataatg ccgccgatgg catttttttc cccgcccttg agcaaaatat
     6121 gatgggtgcg gtgttaatta acgaaaatga tgaagtgatg tttttcaacc ccgccgcaga
     6181 gaagctctgg gggtacaaac gtgaagaagt cattggcaat aacattgata tgctgattcc
     6241 gcgggatttg cgtcctgcgc atcctgaata cattcgtcat aaccgtgaag gcggtaaagc
     6301 gcgtgtcgag gggatgagtc gggagctgca gctggagaaa aaagacggca gtaaaatctg
     6361 gacccgtttt gcgctatcga aagtgagcgc cgaggggaaa gtttattacc tggcgctggt
     6421 acgggatgcc agcgtagaaa tggcgcaaaa agaacagact cgacaattga ttattgccgt
     6481 tgaccatctc gaccgaccgg tgattgtcct cgatccggaa cgccatattg tgcagtgcaa
     6541 tcgcgcattt accgaaatgt ttggttactg cattagcgaa gccagcggta tgcagcccga
     6601 tacactcctg aacattcctg aattccctgc cgataaccgc attcgtttac aacagttgct
     6661 atggaaaacc gcccgcgatc aggacgaatt tctgctgttg acgcgcaccg gtgaaaaaat
     6721 ctggattaaa gcctctatca gcccggttta tgacgtgctc gcgcatctgc agaacctggt
     6781 aatgactttc tcggatatca ccgaagaacg gcaaatccgc cagcttgaag gcaatattct
     6841 cgccgccatg tgcagcagcc cgccatttca tgaaatgggg gaaatcattt gtcgtaacat
     6901 cgaatctgtt ctcaacgaat cgcatgtttc gctgttcgca ctgcgcaacg ggatgccgat
     6961 acactgggcg tcatcttcgc acggtgcaga agttcaaaat gcgcaaagct ggtcagcgac
     7021 cattcgtcag cgtgatggcg cgcctgcggg gatcctgcaa attaaaacct cgtcaggagc
     7081 agaaaccagc gcctttatcg aacgcgtggc agatatcagt cagcatatgg ccgcgctggc
     7141 gctggaacag gaaaaaagcc gccagcatat tgaacaactc atccaatttg atccgatgac
     7201 cggtctgcca aatcgcaata acctgcacaa ttacctcgat gacctggtcg acaaagccgt
     7261 ctctccggtg gtgtatctca tcggtgttga ccatattcag gatgtgattg atagccttgg
     7321 ctatgcgtgg gccgatcagg cattgctgga agtggtcaat cgctttcgtg aaaaactcaa
     7381 accggatcag tatctctgtc gtatcgaagg tacgcagttt gtcctcgtga gcctggaaaa
     7441 cgacgtcagt aacattaccc agatcgccga tgagctacgg aatgtggtca gcaagccgat
     7501 aatgattgac gataaaccat tcccgcttac cttgagtatt ggcatcagct acgacgtggg
     7561 taaaaaccgc gattacctac tctccactgc tcacaatgca atggattata ttcgcaagaa
     7621 tggcggtaac ggctggcagt tcttcagccc ggcgatgaac gaaatggtaa aagagcgttt
     7681 ggttttaggc gcagcgctga aagaagcgat tagcaataac caactgaaac ttgtttacca
     7741 gccgcaaatc ttcgcagaaa cgggtgaact gtacggcatc gaagcccttg cgcgctggca
     7801 cgatccccag catggtcatg tgcccccttc acggtttatt cctctcgcag aagagattgg
     7861 tgaaatcgaa aatattgggc gctgggtcat cgcggaagct tgccgtcagt tagcagaatg
     7921 gcgtagccag aatattcata tcccggcgct ttccgttaac ttgtcggcac tgcactttcg
     7981 cagtaatcaa ctgcctaatc aggtgtctga tgcaatgcac gcctggggta ttgacggcca
     8041 ccagctgacg gtagaaatca cggaaagcat gatgatggaa cacgataccg aaatctttaa
     8101 gcgcattcag atcctgcgtg atatgggcgt gggcttatcg gtagatgatt ttggtacggg
     8161 cttttccgga ttatcccgct tagtcagtct tccggtaacg gaaatcaaaa ttgacaaaag
     8221 ttttgtcgat cgttgtctga cggaaaaacg catcctggcc ttacttgaag ccattaccag
     8281 cattgggcaa agcctcaatt taaccgtcgt ggcggaaggg gtcgaaacca aagagcaatt
     8341 tgagatgcta cgtaagatcc actgtcgcgt tattcaggga tatttctttt cccgccccct
     8401 tcccgccgaa gaaattccag gctggatgag cagcgtgtta ccgctgaaaa tctgacaaat
     8461 tcctctcgcc cgcactcgcg ggttttcctt taaggtgaca ctgtcactta aatactgtga
     8521 tttcagctac gattccggga gattccttcc ttaacttccc ctcttgcacc aaaactgcac
     8581 tacgctgcac aaatgttgat caaaagttaa aaaatataac tttaagccag cattctggcg
     8641 cttctcccgg catggcatga gatctgcata agcggaaagc gcagcaattt ttgtcttata
     8701 caggaaccgt ttatgtcgga taccaccgaa ctggttgatt tagccgtaat cttccctgat
     8761 ctggagatcg aattgaaata cgcctgcgct gataacatca caggtaaagc tatttatcag
     8821 caagcgcgtt gtctgttaca caaggatgcg attaccgcgc tggcgaaaag tatcagcatc
     8881 gcccagctgt caggcttaca actggtgatt tacgatgcgt atcgcccaca acaagcacag
     8941 gcgatgttgt ggcaagcctg cccagacccg caatatgttg ttgatgtgac ggtcggttct
     9001 aatcacagcc gtggcacggc gatcgacctg acgcttcgtg atgaacacgg gaacatcctc
     9061 gatatgggcg cagggttcga tgaaatgcac gagcgctccc atgcctatca cccttccgtc
     9121 ccgcccgccg ctcagcgcaa tcggctgttg ctgaatgcga taatgactgg tggcggtttt
     9181 gtcggtatct ccagcgaatg gtggcacttc gaattacccc aggcagcgag ttaccctctg
     9241 ctcgctgatc aattcacctg ttttatatcc cctggcacac aacacgtcag ttaatcagga
     9301 aactgtcatg aagagatcga taccgtttcg tcccacattg ctcgcgctcg tccttgccac
     9361 aaatttcccg gttgcgcacg ccgccgtacc gaaagatatg ctggtgattg gtaaggccgc
     9421 cgatccacaa accctcgacc cggcggtaac aatagataat aacgactgga cggtgaccta
     9481 cccgtcttat cagcggctgg ttcagtacaa aacggacggt gataaaggct caaccgacgt
     9541 tgaaggcgat ctggcaagta gctggaaagc gtctgacgat caaaaagagt ggacgttcac
     9601 cctgaaggac aatgctaaat ttgccgatgg cacaccggtc actgccgaag cagtaaaact
     9661 ctcttttgag cggctactaa aaatcggcca ggggccagca gaagcatttc ccaaagattt
     9721 aaagattgat gctcccgacg aacatacggt gaagtttacc cttagccagc cattcgcacc
     9781 gttcctctac acgctggcga atgacggtgc atccattatc aatccggcgg tcttaaagga
     9841 acatgcagcg gatgatgctc gcggcttcct cgcgcaaaat accgccggtt ccggaccatt
     9901 tatgctgaaa agctggcaaa aaggtcagca attagttctg gtgccaaatc cgcattaccc
     9961 cggcaataaa ccgaacttta agcgagtatc ggtaaaaatt atcggtgaaa gtgcctcccg
    10021 tcgcctgcag ctctcccgtg gcgacattga cattgccgat gcgctgccgg tggatcaact
    10081 caacgccctg aagcaggaaa ataaagtcaa tgtggcagag tatccgtcac tgcgcgttac
    10141 ctatctgtat ctgaataaca gcaaagcgcc tcttaatcag gcggatctgc gtcgggccat
    10201 ttcctggtct accgattatc agggcatggt taacggcatt ctgagtggta acggaaaaca
    10261 gatgcgcggc ccgattccgg aaggcatgtg gggctacgat gcgacggcaa tgcaatacaa
    10321 ccatgacgaa acgaaagcca aagccgaatg ggataaagtg acgagcaaac ccaccagcct
    10381 gacgtttctc tactccgata acgatccgaa ctgggagcct attgctttgg cgacacaatc
    10441 cagtctcaac aagctgggca tcaatgtgaa gctggaaaag ctggcgaacg ccaccatgcg
    10501 cgacagagtg ggtaaaggtg attacgacat tgcgattggc aactggagtc cggattttgc
    10561 cgacccgtat atgtttatga attactggtt tgagtcagac aaaaaaggtc tgccgggtaa
    10621 ccgctcgttc tatgaaaaca gtgaggtcga taagttactg cgcaatgcgc ttgcgaccac
    10681 cgaccagacg cagcgtaccc gggactacca gcaggcacag aaaatcgtca ttgatgacgc
    10741 tgcttatgtg tacctgttcc agaaaaacta ccaactggcg atgaacaaag aggtgaaagg
    10801 ctttgtgttc aatcccatgc tggaacaggt cttcaatatc aataccatga gtaaataacg
    10861 tgaccttctg gagtatttta cgccaacgct gctgggggct ggtgctcgtg gtggcgggcg
    10921 tctgcgtgat tacgtttatt atctcgcatc tgatccctgg cgatccggcg cggttactgg
    10981 cgggtgaccg cgccagcgat gctatcgtgg aaaatattcg ccagcaactg ggactggacc
    11041 agccactgta tgtacagttt taccgctacg tcagcgacct gtttcatggt gacctgggaa
    11101 catccattcg taccgggcgt ccggtgctgg aagagttgcg tatatttttc ccggcgacgc
    11161 tggagctggc tttttgtgcc ctgctgctgg cactcctgat tggcatcccg ctgggcatac
    11221 tctctgcagt ctggcgaaat cgctggctgg atcatctggt gcgaataatg gccattaccg
    11281 gaatctccac acctgcgttc tggcttgggc tgggcgtcat tgtgctgttt tatggtcatc
    11341 tgcaaattct tcccggcggc ggaaggcttg atgactggct ggatccacca acgcacgtta
    11401 ccggctttta tctgctcgat gcgctgcttg aaggcaacgg tgaagtcttc ttcaatgcgt
    11461 tgcaacatct catcttaccg gcattaacgc tggcgttcgt tcacctggga attgtcgctc
    11521 gccagatccg ctcagcgatg ctggaacaat tgagtgaaga ctacattcgt accgcccggg
    11581 ccagcggctt gcccggctgg tatatcgttt tatgttatgc gctacccaat gcgttgatcc
    11641 catcgattac cgtattgggt ttggcgctgg gcgatttgtt gtatggcgca gtgctcaccg
    11701 aaaccgtttt tgcctggccc ggaatgggtg catgggtagt aacatcaata caggcgctcg
    11761 acttcccggc agtgatgggc tttgccgtcg tggtttcatt tgcttatgtg ctggtcaacc
    11821 tggtggtgga tttgctctat ttgtggattg atccgcgtat cggacgtgga ggtggtgaat
    11881 gatgctaagc gaggaaacgt ccgccgtacg cccacaaaaa caaacgcgat ttaacggtgc
    11941 aaaactggta tggatgctga aaggcagtcc gctcaccgtg accggcgcag tcatcattgt
    12001 attaatgcta ttgatgatga ttttttcacc gtggctggcg acgcatgatc ccaacgccat
    12061 tgatttaacc gcccgccttt tgccgccttc tgcggcgcac tggtttggca ccgatgaagt
    12121 gggacgcgat ctgttcagcc gcgtactggt cggcagtcag caatcaattc tcgccggatt
    12181 agtggtggtc gccattgcgg gtatgattgg ttcgctactc ggatgtctat ccggtgtgct
    12241 tggcggacgc gcagacgcca tcatcatgcg catcatggac attatgctgt cgattccttc
    12301 gttggtactg acaatggcac tggctgccgc tctcgggccg agtttgttta acgccatgct
    12361 ggcgattgct attgtgcgaa ttccctttta tgtgcgcctg gcgcgggggc aagcattagt
    12421 tgtacgccag tatacctatg ttcaggcggc gaaaaccttt ggcgcgtctc gttggcatct
    12481 gatcaactgg catattttac gtaactccct accgccgctg atcgtgcagg catcgctgga
    12541 tatcggtagc gcgattttaa tggccgccac gttgggattt attggcctgg gtgctcaaca
    12601 accgagtgct gaatggggcg cgatggtagc aaatggtcgc aactatgtac tcgatcagtg
    12661 gtggtattgc gcatttccgg gggcagcgat tttgcttacc gccgtcgggt ttaatctctt
    12721 tggtgatggt attcgcgatc tgcttgaccc gaaagcagga ggaaagcagt catgacccaa
    12781 cccgttctgg acattcaaca gctgcatttg agtttccccg gttttaacgg tgatgttcac
    12841 gcgctcaaca atgtgtcctt gcagattaac cgcggcgaaa ttgtcggtct ggtgggagaa
    12901 tccggctcag gtaaatcagt caccgcaatg ctgattatgc gtctgctaca gacgggcagt
    12961 tattgcgtac atcgggggca gatttcactg ctgggagacg atgttcttaa cgctcgggaa
    13021 aaacagcttc gtcagtggcg cggcgcacga gtggcgatga tctttcagga accgatgacc
    13081 gccctcaatc cgacacttcg aataggtctt cagatgatgg acgtgatccg ccatcatcaa
    13141 ccaataagtc gtcgggaagc cagagctaaa gcgattgccc tgctggaaga gatgcaaatc
    13201 ccggatgccg tggaagttat gtcgcgctat ccgtttgagc tttcaggtgg tatgcgccag
    13261 cgggtaatga ttgcgctggc attctcctgc gagccgcaat tgattattgc cgacgaaccg
    13321 actacggcgc tggacgtcac ggtgcagttg caggtactgc gtttgcttaa acataaagcc
    13381 cgcgccagtg gaactgcggt tctgttcatc agccatgata tggccgtggt gtcgcaactg
    13441 tgcgatagcg tttacgtgat gtatgccgga agcgtaattg aaagcggcgt gacggcagat
    13501 gttatccatc atccccggca tccgtatacc attggtttgc tccaatgcgc accagaacat
    13561 ggagtaccac gccagctatt acccgccatt ccagggacgg taccaaacct cacccatttg
    13621 cctgaaggct gcgcttttcg cgatcgttgc tatgcggcag gtgcacagtg tgaaaacgtc
    13681 ccggcgctga cagcgtgtgg tgacaacaac cagcgctgcg cctgttggta tccgcagcag
    13741 gaggtcataa gtgtctgaca cgttattaac gttacgcgac gtccatatca atttcccggc
    13801 ccgtaaaaac tggcttggta aaactacgga acatgttcat gccattaatg gtattgattt
    13861 acagatccgc cgtggtgaaa ccttagggat cgtcggcgag tcaggctgcg gcaaaagcac
    13921 cctcgcacag cttttaatgg gcatgctgca accgagccac gggcagtaca tccgttcagg
    13981 ctcacaacgc attatgcaga tggtgtttca ggacccgctc tcttcgctta atccgcgctt
    14041 accggtgtgg cgcatcatca cagaaccgct ctggatagct aagcgtagta gtgaacaaca
    14101 gcggcgagcg ttagcagagg agttggctgt gcaggtgggt attcgtccgg agtatctcga
    14161 ccgcctgcct catgcgttct ccggcgggca gcggcaacgc atcgccattg ccagagcact
    14221 ctcttcgcag cctgacgtga ttgtgcttga tgagccaacc tctgcactgg atatctccgt
    14281 gcaggcgcag atcctcaatt tactggtaac gctacaggta aatcgcgggc tgacctatgt
    14341 gctgatctca cacaatgtct cggtgattcg tcatatgagc gatcgggtag cggtgatgta
    14401 tctcgggcag attgtagaac tgggcgacgc gcagcaggtg ttgacggcac ctgcacatcc
    14461 atacacccga ttattgctgg attccctccc cgccattgat aaaccgctgg aggaagaatg
    14521 ggcattacgt aaaacggatc tgccgggaaa ccgcacgttg ccgcaaggct gttttttcta
    14581 cgaacgttgc cctctggcaa cccacggatg tgaagtccgg caatcattaa caataaggga
    14641 ggacggacgt gagatccggt gctggcgggc gctgtagaga tgctaacaac gcatcaggca
    14701 ttcacgcgcc tgacgcgtca tccggcaatg ctttacgatt tcaactggta atcaagcgta
    14761 atttccgctt tcagtacctg agaaaccggg catcctgctt ttgctttctg gatgatgccg
    14821 tcaaaggtag aggcatcaat acccggcacc gcaacttcac tcttcagtgc gattttcgta
    14881 atcgcaaaac cggcatccac tttatccagc gacacatcgg cggtggtatc aatcgatgtt
    14941 ggcgtaaatc ccgcttcccc cagcattaat gaaagcgcca ttgagaaaca tgcggcatgc
    15001 gctgcgccaa tcagttcttc agggttagtt cctttttcgc cttcaaaacg cgtgttaaat
    15061 ccatacggct gttggttcag cacaccactc tcggtggata ctgttccctt cccgcgtttg
    15121 atatcgcctt cccagtgtgc ctgacctttc ttatggattg tcattgttgc tctcctgtgg
    15181 gcttaaaaag gaaattatag actacgtgag aaacagcacg aggataagca ggatattccg
    15241 aataaaaatc cggcagaaat attacttctg cacttaaatt aaatttccac aatagataac
    15301 cgggaatata taacccaaga gatattgcat taatattaat caactcacca caataataat
    15361 acctatcaat atcatgaggt taaaatataa aaatcatcaa ccaggactaa tcttaacaac
    15421 gaagcggcaa atatttgcca tgctgaatgt gctttataaa tctgcgatcc gtagcagaca
    15481 ccataaatac acagacacgg agaatcacta tgtttactta ttatcaggca gaaaattcaa
    15541 cagcagaacc cgctctggtt aatgccattg agcaaggcct tcgggcagag cacggtgttg
    15601 tcactgaaga tgacattctc atggagctga ccaaatgggt ggaagcttct gataacgaca
    15661 tcctcagtga tatctaccag caaacgatca attatgtggt cagtggccag caccctacgc
    15721 tttaaggtgc tatgcttgat cggcaaccta atttaggggt ttagcacgtg tttcttcgct
    15781 acggcgatgt tgtccttaaa actagcaaca ggattgagga gttaaaatga aatcgaaccg
    15841 tcaggcacgt catattcttg gactggacca taaaatttct aaccagcgca aaatagttac
    15901 cgaaggtgac aaatccagcg tggtaaataa cccaaccggc agaaaacgcc ccgctgaaaa
    15961 gtaattcata accatcagtc ctcaatgacg attaaacacc attgcctgcg caatggtgtt
    16021 tttgttttta tctgctttat acttggggcc gacgccctgg tggtaaagca aagacgataa
    16081 aagcgtgcca gggatggata ttcaaaaaag agtgagtgac atggaaccaa aaacaaaaaa
    16141 acagcgttcg ctttatatcc cttacgctgg ccctgtactg ctggaatttc cgttgttgaa
    16201 taaaggcagt gccttcagca tggaagaacg ccgtaacttc aacctgctgg ggttactgcc
    16261 ggaagtggtc gaaaccatcg aagaacaagc ggaacgagca tggatccagt atcagggatt
    16321 caaaaccgaa atcgacaaac acatctacct gcgtaacatc caggacacta acgaaaccct
    16381 cttctaccgt ctggtaaaca atcatcttga tgagatgatg cctgttattt ataccccaac
    16441 cgtcggcgca gcctgtgagc gtttttctga gatctaccgc cgttcacgcg gcgtgtttat
    16501 ctcttaccag aaccggcaca atatggacga tattctgcaa aacgtgccga accataatat
    16561 taaagtgatt gtggtgactg acggtgaacg tattctgggg cttggtgacc agggcatcgg
    16621 tgggatgggc attccaatcg gtaaactgtc gctctatacc gcctgtggcg gcatcagccc
    16681 ggcgtatacc cttccggtgg tgctggatgt cgggaccaac aaccagcagc tgcttaacga
    16741 tccgctgtat atgggctggc gtaatccacg tatcactgac gatgaatact atgaattcgt
    16801 tgatgaattt atccaggctg tgaaacaacg ctggccggac gtgctgttgc agtttgaaga
    16861 ctttgctcaa aaaaatgcga tgccgttact taaccgctat cgcaatgaaa tttgttcttt
    16921 taacgatgac attcagggca ctgcggcggt aacagtcggc acactgatcg cagccagccg
    16981 cgcggcaggt ggtcagttaa gcgagaaaaa aatcgtcttc cttggcgcag gttcagcggg
    17041 atgcggcatt gccgaaatga tcatctccca gacccagcgc gaaggattaa gcgaggaagc
    17101 ggcgcggcag aaagtcttta tggtcgatcg ctttggcttg ctgaccgaca agatgccgaa
    17161 cctgctgcct ttccagacca aactggtgca gaagcgcgaa aacctcagtg actgggatac
    17221 cgacagcgat gtgttgtcac tgctggatgt ggtgcgcaat gtaaaaccag atattctgat
    17281 tggcgtctca ggacagaccg ggctgtttac ggaagagatc attcgtgaga tgcataaaca
    17341 ctgtccgcgt ccgatcgtga tgccgctgtc taacccgacg tcacgcgtgg aagccacacc
    17401 gcaggacatt atcgcctgga ccgaaggtaa cgcgctggtc gccactggca gcccgtttaa
    17461 tccagtggta tggaaagata aaatctaccc tatcgcccag tgtaacaacg cctttatttt
    17521 cccgggcatc ggcctggggg ttattgcttc cggcgcgtca cgtatcaccg atgagatgct
    17581 gatgtcggca agtgaaacgc ttgctcagta ttcgccgctg gtcctgaacg gcgaaggtct
    17641 ggtactaccg gaactgaaag atattcagaa agtctcccgc gcaattgcgt ttgcggttgg
    17701 caaaatggcg cagcagcaag gcgtggcggt gaaaacgtct gccgaagctc tgcaacaggc
    17761 cattgatgat aatttctggc aagccgaata ccgcgactac cgccgtacct ccatctaagc
    17821 ctgcgcccgg tagtgaaggc taccgggcta tttctctctc cctttttcag atctcatcca
    17881 tactgggtag tggcgaataa atctcatttg cctcacctgc tatgcagaac atcatccgaa
    17941 aaggaggaac tatgaaggct gcagttgtta cgaaggatca tcacgttgac gttacggata
    18001 aaacactgcg ctcactgaaa catggcgaag ccctgctgaa aatggagtgt tgtggtgtat
    18061 gtcataccga tcttcatgtt aagaatggcg attttggtga caaaactggc gtaattctgg
    18121 gccatgaagg catcggtgtg gtggcagaag ttggccctgg tgtcacctca ttaaaaccag
    18181 gcgatcgtgc cagcgtggcg tggttctacg aaggatgcgg tcattgcgaa tactgtaata
    18241 gtggtaacga aacgctctgc cgttcagtta aaaatgccgg atacagcgtt gatggcggga
    18301 tggcggaaga gtgcatcgtg gtcgccgatt acgcggtaaa agtgccagat ggtctggact
    18361 cggcggcggc cagcagcatt acctgtgcgg gggtcaccac ctacaaagcc gttaaactgt
    18421 caaaaattcg tccagggcag tggattgcta tctacggtct tggcggtctg ggtaacctcg
    18481 ctctgcaata cgcgaagaat gtctttaacg cgaaagtgat cgccattgat gtcaatgatg
    18541 agcagttaaa actggcaacc gaaatgggtg cagatttagc gattaactca cgcaccgaag
    18601 acgccgccaa aattgtgcag gagaaaaccg gtggcgctca cgctgcggtg gtaacagcag
    18661 ttgctaaagc tgcgtttaac tcggcagttg atgctgtccg tgcaggcggt cgtgttgtgg
    18721 ctgtcggtct gccgccggag tctatgagcc tggatatccc acgccttgtg ctggatggca
    18781 ttgaagtggt cggttcgctg gtcggcacgc gccaggatct aaccgaagcc ttccagtttg
    18841 ccgccgaagg caaagtggtg ccgaaagtcg ccctgcgtcc gttagcggac atcaacacca
    18901 tctttaccga gatggaagaa ggcaaaatcc gtggccgtat ggtgattgat ttccgccgtt
    18961 aagaggcctt tgctgcgagt gccagtcctg gtgtcgcagc atcgcactct ctccgacatt
    19021 aaatggctaa atggattatt gttccttcct acgcaacaat aatgatagtg ttcctgatga
    19081 aggaacacta ctgagagtaa agacactgat gaaaatggcc aatcatcccc gcccggggga
    19141 cattattcag gaatcactgg acgaacttaa tgtcagcctg cgcgagtttg ccagagcaat
    19201 ggaaattgct ccctcaacgg caagccgatt gctgaccgga aaagcagctt tgacaccaga
    19261 aatggcgatt aaactttccg tggtgatcgg cagttcgccg caaatgtggc tgaatctgca
    19321 aaacgcctgg agtctggcag aggcagaaaa aacggtggat gtgtcgcgac tacgccgtct
    19381 ggttacgcaa taaaaaaatg gcgcttctta aagcgccatt ttcagcttaa agttcaaaag
    19441 agattatatc ccttcttcac tctctttttt cgcttctgcc ttctcgattt cacgatacca
    19501 gcgcggatgg tgtttcttcg cccagcgacg gctcaccttc ccttcgatca tccctttaat
    19561 cgaccctttc acccagaatg ccatatacat atggatcagg atggcgtgga tcaggatgat
    19621 acccgcagcc gcgtggatca gcaggctgta gcgaacaacc tgcatcggga agtactgcgc
    19681 aaagtacgga cgccagataa tcaccccggt caccagcagc acgaaaatca tgctcatgat
    19741 cgaccagaac atcatctttt gcccggcgtt gtacttaccg acatccgcca ctttatgctc
    19801 attgcctttc aatacttcga caatgttcaa cagccacgga atatctttct tatccgggat
    19861 gttgtgatgc acaaaacgca caaacataaa catcagtgcg acgaaaatcg caatgccgaa
    19921 aaacgggtgc aaaatgcgtc ccatctgcgg cgtaccgaag gtttgcgtca gccattgcag
    19981 cgtcgggaag aagaacgaaa tcccggacag cgccaccagg aagaagcaaa tcaccacggt
    20041 ccagtgacag gcgcgatcaa taaatttggt gcgcacaatc attttcgact tactcatgat
    20101 gatcctcctc gtcatcgtcc acttccttat tcgggccaat accgatgtag tggaaaatca
    20161 acccggcaaa agtggcaata aagccagccg ctgccagcgg tttcaacgcg cctttccaca
    20221 ggcttaccga ggtgtcgatc ttcggatctt tcggcagacc gtgatacagc tccggctgat
    20281 cggcgtgatg cagcacgtac ataacgtgcg taccaccgac cccttccggg ttgtagacgc
    20341 cagcatgttc gtaaccacgc gctttcagtt tcgccacgcg ctgttccgcc agctccagca
    20401 tctccttctt ggtgccgaag tggatagccc cggtcggaca ggttttcaca caagccggtt
    20461 cctggccgac gctgacgcga tcgacgcaga gcgtgcattt atatacccgg ttatcctctt
    20521 tgttgaggcg cggaatatta aacggacacc cggcaatgca gtaaccacag ccgatgcagt
    20581 tttccgactg gaaatcgaca atcccgttag cgtactgaat gattgcacca gcagacgggc
    20641 acgccttcag gcagccggga tcttcacagt gcatacagcc gtctttacgg atcagccact
    20701 ccagcttgcc gttctgttcg gtttcgctaa agcgcatcac cgtccaggac ttggcgctca
    20761 gatcggcggg gttatcgtaa accccgacgc agtgccccac ttcatcacgg atgtcgttcc
    20821 actccgaaca cgccacctga caggctttac agccgataca ggtggaaacg tcgataagtt
    20881 ttgcgacttc tgctttgtaa tcacgcacct gagaaggcgg cgtgatggag ttagttgcgg
    20941 accttttgat aatgtcctgc gtttccatag ccatctgttc gcccccttac gccttctcga
    21001 tgttgactaa gaacgcttta tattccggcg tttgcgagtt tgcatcaccg acattcggcg
    21061 tcagagtgtt agcgatataa cctttacgcg cgacaccctc aaagccccag tggattggaa
    21121 tacccaccgt ttcaacctgc tgaccattta cattcagtgg tttcagacga cgcgttacca
    21181 cagccaccgc gcggataaag ccacgcttgc ttgagacagt gacacgatcg ccattattaa
    21241 tgcctttcgc cgccgccagc gtttcgctga tttccacaaa ctgttccggc tgagcaattg
    21301 cgttgagcaa tgcgtgcttg gtccaggtgt ggaagtgctc ggtcagacga taggtcgtac
    21361 ccacatacgg gaactgctct tttttaccca tccgcagcgc gtcttgttca tacagacgaa
    21421 caaccgggtt agacaccacg ttcggatgca gcgggttagt gcccagcggc gtttcaattg
    21481 gctcgtagtg ttccgggaac ggaccttccg ccattttgtt gatggcaaac aggcgtccca
    21541 tcccttccgg ctgcatgata aacggcccgg ttggcgtacc cggtgcggca ttgccgaagt
    21601 ccggaatatc gttacccgtc cacttgctgc cgttccactg gatcagcatc cgtttcggat
    21661 cccacggttt accgttgata tccgccgaag cacggttgta cagcacgcga cggttgagcg
    21721 gccacgccca ggcccatccc agcgtattcc ccagaccgga cgggtcggag ttatcgcggt
    21781 tagccatctg gttgccctgc tctgtccagc taccggtgta gatccagcaa gaagatgcgg
    21841 ttgtaccgtc atcacgcaga tgcgcaaagc tactcagcaa ctgacctttc ttcgcaatca
    21901 gcacgccatt tgcgtcatag agatcttcca gcgcatagcc gttgttctct tttgccactt
    21961 cgtcagattg cggttcgtgc ggctgcttgt agttccagct catcttcatc agcggttcta
    22021 cgcctttacc accttcggcc tggtacaact cgcgcagatg atggtagata cccgccagaa
    22081 tttcgccgtc gttacgcgct tcgcccggcg cgtcctgacc tttccagtgc cactgcaacc
    22141 agcgaccgga gttagcgata gaaccatcct cttcagcaaa gcaggtcgaa ggcagacgga
    22201 atacttcagt ctgaatagac gccggatcga catcgttcga ctcgccgtgg ttctgccaga
    22261 aggtagaggt ttcagtcacc agcggatcga taaccaccat gtacttcagc ttgctcaggc
    22321 agctcaccac tttgtttttg tccgggaagg acgcaaccgg gttaaagccc tggcagaaat
    22381 aaccggtgac tttgccttca tccatcatgt tgaaatactt gatgacgtcg taggtctggt
    22441 cccacttcgg cagccagtca tagccccagt tgttctcttt ctgcgcggca tcgccataga
    22501 aagatttcat caggctaacg aagaacttcg gatagttgct ccagtagttc acctgatcag
    22561 ctagcgtcgc tttcggcgtg ttcgcttcca gatacgactg caaatcaacc tgtttttctg
    22621 acggcagcgt cagataacct ggcaggctgg tagagagcag gcctaagtca gtcaagccct
    22681 gaatgttgga gtgaccacgc aatgcgttca cgccgccacc ggccataccc atgttaccga
    22741 gcagcaactg gatcatcgcc atagtacgga tgttctgcgc acccacagtg tgctgcgtcc
    22801 agcccagcgc gtacaggaag gtggttgtgc gatccggtgc gctggtggag gccagcactt
    22861 cacacacttt caggaagtcg gcttttggcg taccacagat gttttcaaca acgtccggcg
    22921 tgtagcggga aacgtgcgct ttcagcaggt tccacacaca gcgcggatga gtcagtgttt
    22981 catcgcgttt cgcatagccg ttttcatcga actgatagtt ccaggacgat ttatcgtatt
    23041 gccgtttttc agcgtcgtag ccgctgaaca gaccgtcttc gaaagcaaaa tcatcacgca
    23101 ccagcaggct ggcgttggtg taatgcttaa cgtattcggc gttgattttg tcgttttcga
    23161 tcaggtagcg caaaacgcca gacaggaacg taatgtccgt accggaacga ataggtgcgt
    23221 aaatatccgc cacagaagcg gtacgcgtaa aacgaggatc gacaacgatc aaggttgcat
    23281 cgttgttgtt tttcgcttcc atcgcccagc ggaaaccgac gggatgcgct tcagcagcgt
    23341 taccgcccat taccattacg acgttagcgt ttttgatatc cacccagtgg ttggtcatcg
    23401 caccgcgacc aaatgttgga gcaagacttg ctaccgttgg tccgtgtcag acgcgcgcct
    23461 ggttgtctac cgccagcatc ccgagggagc gggcaaattt ctgtgtcagc atcccggttt
    23521 cgttgctggc accggaggca cacagcatac cggtagaaag ccaacggttt accgttacgc
    23581 cctgctcgtt cttttcaata aagttagcgt cacggtcagc tttcatcagc tttgcaatac
    23641 gggagaatgc ttcttcccag ctaatgcgct gccatttgtc agaacctggc gcacgatatt
    23701 ccgggtagcg cagacggttt tcgctgttga cgtaatccag caaaccggcc ccttttgggc
    23761 acagcgcacc acggcttacc ggatgatccg ggtcaccttc aatgtgataa atcgcttctc
    23821 tggcgttttt cgcgccatca cccaggctat acatcaatag cccgcaacct acggaacagt
    23881 atgtgcaggt gttacggatc tctttagcgc gtaataattt gtagtttcgc gcctgagcca
    23941 gtgcttgctt cggggcaaag cccaatgccg ctaccgttgt tccagccata ccgcccgcgc
    24001 agattttaaa aaattgtctg cgactgacgt ccattgcttt cctctttttt caggggtatt
    24061 actgcgcgag gaaactaaca gtaaaattct gaatcttttt gcgcgaaatc aaaaagaaca
    24121 cgtgtttgcc acaaaataat ccgcctgcgc aaattgacct acctcaatag cggtagaaaa
    24181 acgcaccact gcctgacagg ccagttaaaa aaatgctata aaattcagct taatttttaa
    24241 cggcaagaga gacaaaacag cgagcatgac acgacaaaaa gcaacgctca tagggctaat
    24301 agcgatcgtc ctgtggagca cgatggtagg attgattcgc ggtgtcagcg aggggctcgg
    24361 cccggtcggc ggcgcaactg ctatctattc attaagcggg ctgctgttaa tcttcacggt
    24421 tggatttccg cgtattcggc agattccgaa aggctattta ctcgccggga gtctgttatt
    24481 cgtcagctat gaaatctgtc tggcgctttc cttagggtat gcggcgaccc gtcatcaggc
    24541 gattgaagtg ggtatggtga actatctatg gcccagcctg acaattctct ttgccattct
    24601 gtttaatggt cagaaaacca actggctgat tgtaccagga ttattattag ccctggtcgg
    24661 cgtctgctgg gtgttaggcg gtgataatgg gttacattat gatgaaatca tcaataatat
    24721 taccaccagc ccattgagtt atttcctggc gtttattggt gcgtttatct gggcagccta
    24781 ttgcacagta acgaataaat acgcacgcgg atttaacgga attaccgttt ttgtcctgct
    24841 aacgggagca agtctgtggg tttactattt tctcacgcca caaccagaaa tggtatttag
    24901 cacgcccgtc atgattaaac tcatctctgc ggcatttacc ttaggatttg cttatgctgc
    24961 atggaatgtc ggtatattgc atggcaatgt caccataatg gcggtaggct cgtattttac
    25021 acctgtactt tcctcagcgc ttgcagccgt gctgctcagc gccccactgt cgttctcgtt
    25081 ctggcaaggc gcgctaatgg tctgcggcgg ttccctgctc tgctggctgg cgacacgtcg
    25141 tggttaaaat aattgccggg tctacggccc ggcagttaat cagataaatt ccgacaatat
    25201 taaaaaataa atttcaaata ccagtaattc accttatatc tcatt
//
LOCUS       DAPGUL010000061        25193 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.061, whole genome shotgun sequence.
ACCESSION   DAPGUL010000061 DAPGUL010000000
VERSION     DAPGUL010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25193
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.061"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..265)
                     /gene="iss"
                     /locus_tag="RHX21_002717"
     CDS             complement(<1..265)
                     /gene="iss"
                     /locus_tag="RHX21_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="increased serum survival lipoprotein Iss"
                     /protein_id="HDV1987878.1"
                     /translation="MKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVS
                     GIGQQKTVDAAKICGGAENVVKTETQQTFVNGLLGFITLGIYTP"
     gene            complement(628..822)
                     /locus_tag="RHX21_002718"
     CDS             complement(628..822)
                     /locus_tag="RHX21_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlcI/YnfO family protein"
                     /protein_id="HDV1987879.1"
                     /translation="MSTKNRTRRTTTRNIRFPNQMIEQINIALEQKGSGNFSAWVIEA
                     CRRRLTSEKRAYTSIQSDDE"
     gene            1211..1756
                     /locus_tag="RHX21_002719"
     CDS             1211..1756
                     /locus_tag="RHX21_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein"
                     /protein_id="HDV1987880.1"
                     /translation="MEVNKKQLADIFGASIRTIQNWQEQGMPVLRGGGKGNEVLYDSA
                     AVIRWYAERDAEIENEKLCREVEELRQASETDLQPGTIEYERHRLTRAQADAQELKNA
                     RDSAEVVETAFCTFVLSRIAGEIASILDGIPLSVQRRFPELENRHVDFLKRDIIKAMN
                     KAAALDELIPGLLSEYIEQSG"
     gene            1731..3656
                     /locus_tag="RHX21_002720"
     CDS             1731..3656
                     /locus_tag="RHX21_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit family protein"
                     /protein_id="HDV1987881.1"
                     /translation="MNISNSQVNRLRHFVRAGLRSLFRPEPQTAVEWADANYYLPKES
                     AYQEGRWETLPFQRAIMNAMGSDYIREVNVVKSARVGYSKMLLGVYAYFIEHKQRNTL
                     IWLPTDGDAENFMKTHVEPTIRDIPSLLALAPWYGKKHRDNTLTMKRFSNGRGFWCLG
                     GKAAKNYREKSVDVAGYDELAAFDEDIEQEGSPTFLGDKRIEGSVWPKSIRGSTPKVR
                     GTCQIERAASESPHFMRFHVACPHCGEEQYLKFGDKETPFGLKWTPDDPSSVFYLCEH
                     NACVIRQQELDFTDARYICEKTGIWTRDGILWFSSSGEEIEPPDSVTFHIWTAYSPFT
                     TWVQIVKDWMKTKGDTGKRKTFVNTTLGETWEAKIGERPDAEVMAERKEHYSAPVPDR
                     VAYLTAGIDSQLDRYEMRVWGWGPGEESWLIDRQIIMGRHDDEQTLLRVDEAINKTYT
                     RRNGAEMSISRICWDTGGIDPTIVYERSKKHGLFRVIPIKGASVYGKPVASMPRKRNK
                     NGVYLTEIGTDTAKEQIYNRFTLTPEGDEPLPGAVHFPNNPDIFDLTEAQQLTAEEQV
                     EKWVDGRKKILWDSKKRRNEALDCFVYALAALRISISRWQLDLSALLASLQEEDGAAT
                     NKKTLADYARALSGEDE"
     gene            3653..3859
                     /locus_tag="RHX21_002721"
     CDS             3653..3859
                     /locus_tag="RHX21_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gpW family protein"
                     /protein_id="HDV1987882.1"
                     /translation="MTRQEELAAARAALHDLMTGKRVATVQKDGRRVEFTATSVSDLK
                     KYIAELEVQTGMTQRRRGPAGFYV"
     gene            3856..5457
                     /locus_tag="RHX21_002722"
     CDS             3856..5457
                     /locus_tag="RHX21_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDV1987883.1"
                     /translation="MKTSSIPTLLGPDGMTSLREYAGYHGGGSGFGGQLRAWNPPGES
                     VDAALLPNFTRGNARADDLVRNNGYAANAIQLHQDHIVGSFFRLSHRPSWRYLGIGEE
                     EARAFSREVEAAWKEFAEDDCCCIDVERKRTFTMMIREGVAMHAFNGELFVQATWDTS
                     SSRLFRTQFRMVSPKRISNPNNTGDSRNCRAGVQINDSGAALGYYVSEDGYPGWMPQK
                     WTWIPRDLPGGRASFIHVFEPVEDGQTRGANVFYSVMEQMKMLDTLQNTQLQSAIVKA
                     MYAATIESELDTQSAMDFILGANSQEQRERLTGWIGEIAAYYAAAPVRLGGAKVPHLM
                     PGDSLNLQTAQDTDNGYSVFEQSLLRYIAAGLGVSYEQLSRNYAQMSYSTARASANES
                     WAYFMGRRKFVASRQASQMFLCWLEEAIVRRVVTLPSKARFSFQEARSAWGNCDWIGS
                     GRMAIDGLKEVQEAVMLIEAGLSTYEKECAKRGDDYQEIFAQQVRETMERRAAGLKPP
                     AWAAAAFESGLRQSTEEEKSDSRAA"
     gene            5438..6757
                     /locus_tag="RHX21_002723"
     CDS             5438..6757
                     /locus_tag="RHX21_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S49 family peptidase"
                     /protein_id="HDV1987884.1"
                     /translation="MTAELRNLPHIASMAFNEPLMLEPAYARVFFCALAGQLGISRLT
                     DAVSGDSLTAGEAPAALALSGDDDGPRQARSYQVMNGIAVLPVSGTLVSRTRALQPYS
                     GMTGYNGIIARLQQAASDPMVDGILLDMDTPGGMVAGAFDCADIIARVRDIKPVWALA
                     NDMNCSAGQLLASAASRRLVTQTARTGSIGVMMAHSNYGAALEKQGVEITLIYSGSHK
                     VDGNPYSHLPGDVRETLQSRMDATRRMFAQKVSAYTGLSVQAVLDTEAAVYSGQEAID
                     AGLADELVNSTDAITVMRDALDARKSRLSGGRMTKETQSTTVSATASQADVTDVVQAT
                     EGENASAAQPDVNAQITAAVAAENSRIMGILNCEEAHGREEQARVLAETPGMTVETAR
                     RILAAAPQSAQARSDTALDRLMQGAPAPLAAGNPASDAVNDLLNTPV"
     gene            6767..7099
                     /locus_tag="RHX21_002724"
     CDS             6767..7099
                     /locus_tag="RHX21_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HDV1987885.1"
                     /translation="MTSKETFTHYQPLGNSDPAHTATAPGGLSAKAPAMTPLMLDTST
                     RKLVAWDGTTDGTAVGILAVDADQTSTTLTFYKSGTFRYEDVLWPEAASDETKKRTAF
                     AGTAISIV"
     gene            7155..8180
                     /locus_tag="RHX21_002725"
     CDS             7155..8180
                     /locus_tag="RHX21_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HDV1987886.1"
                     /translation="MSMYTTAQLLAANEQKFKFDPLFLRLFFRESYPFTTEKVYLSQI
                     PGLVNMALYVSPIVSGEVIRSRGGSTSEFTPGYVKPKHEVNPQMTLRRLPDEDPQNLA
                     DPAYRRRRIILQNMRDEELAIAQVEEMQAVSAVLKGKYTMTGEAFDPVEVDMGRSAAN
                     NITQSGGTEWSKRDKSTYDPTDDIEAYALNASGVVNIIVFDPKGWALFRSFKAVKEKL
                     DTRRGSHSELETAVKDLGEAVSYKGMYGDTAIVVYSGQYVENDVKKNFLPDNTMVLGN
                     TQARGLRTYGCIQDADAQREGINASARYPKNWVTTGDPAREFTMIQSAPLMLLADPDA
                     FVSVQLA"
     gene            8222..8617
                     /locus_tag="RHX21_002726"
     CDS             8222..8617
                     /locus_tag="RHX21_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein FI"
                     /protein_id="HDV1987887.1"
                     /translation="MTKDELIARLQVLGEQLNRDVSLTGTKEELVLRVAELEEELDDT
                     DDAAGQDTSVSPENALTGHENEVVSAQPDTVIDTAALVTVVALVTLHTDALHATRDEP
                     VAFVLPGTAFRVSAGVAAEMTEHGLARMQ"
     gene            8629..8982
                     /locus_tag="RHX21_002727"
     CDS             8629..8982
                     /locus_tag="RHX21_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail joining protein"
                     /protein_id="HDV1987888.1"
                     /translation="MADSDNLFDAAIARADETIRGYMGTSATMTSGELSGAVIRGVFD
                     DPENISYAGQGVRVEGSSPSLFVRTDDVRQLRRGDTLTIGEENFWVDRISPDDGGSCH
                     LWLGRGVPPAVNRRR"
     gene            8994..9572
                     /locus_tag="RHX21_002728"
     CDS             8994..9572
                     /locus_tag="RHX21_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV1987889.1"
                     /translation="MAIKGLEQAVENLSRISKTAVPGAAAMAINRVASSAISQSASQV
                     ARETKVRRKLVKERARLKRATVKNPQARIRVNRGDLPVIKLGNARVVLSRRRRRKKGQ
                     RSSLKGGGSVLVVGNRRIPGAFIQQLKNGRWHVMQRVAGKNRYPIDVVKIPMAVPLTT
                     AFKQNIERIRRERLPKELGYALQHQLRMVIKR"
     gene            9569..9964
                     /locus_tag="RHX21_002729"
     CDS             9569..9964
                     /locus_tag="RHX21_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV1987890.1"
                     /translation="MKHTELRAAVLDALEKHDTGATFFDGRPAVFDEADFPAVAVYLT
                     GAEYTGEELDSDTWQAELHIEVFLPAQVPDSELDAWMESRIYPVMSDIPALSDLITSM
                     VASGYDYRRDDDAGLWSSADLTYVITYEM"
     gene            9972..10712
                     /locus_tag="RHX21_002730"
     CDS             9972..10712
                     /locus_tag="RHX21_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV1987891.1"
                     /translation="MPVPNPVMPVKGAGTTLWVYKGNGDPYANPLSDVDWSRLAKVKD
                     LTPGELTAESYDDSYLDDEDADWTATGQGQKSAGDTSFTLAWMPGEQGQQALLAWFNE
                     GDTRAYKIRFPNGTVDVFRGWVSSIGKAVTAKEVITRTVKVTNVGRPSMAEDRSTVTA
                     TTGMTVTPASTSVVKGQSTTLTVAFQPEGATDKSFRAVSADKTKATVSVSGMTITVKG
                     VAAGKVNIPVVSGNGELAAVAEITVTAS"
     gene            10728..11150
                     /locus_tag="RHX21_002731"
     CDS             10728..11150
                     /locus_tag="RHX21_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein G"
                     /protein_id="HDV1987892.1"
                     /translation="MFLKTESFEHNGVTVTLSELSALQRIEHLALMKRQAEQAESDSN
                     RKFTVEDAIRTGAFLVAMSLWHNHPKKTKLPSMNEAVKQIEQEVLTTWPTEAISHAEN
                     VVYRLSGMYEFVVNDAPEQTEDAGPAEPVSAGKCSMVS"
     gene            11132..11566
                     /locus_tag="RHX21_002732"
     CDS             11132..11566
                     /locus_tag="RHX21_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein T"
                     /protein_id="HDV1987893.1"
                     /translation="MFDGELSFALKLAREMGRPDWRAMLAGMSSTEYADWHRFYSTHY
                     FHDVLLDMHFSGLTYTVLSLFFSDPDMHPLDFSLLNRREADEEPEDDVLMQKAAGLAG
                     GVRFGPDGNEVIPASPDVADMTEDDVMLMTVSEGIAGGVRYG"
     gene            11559..14138
                     /locus_tag="RHX21_002733"
     CDS             11559..14138
                     /locus_tag="RHX21_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDV1987894.1"
                     /translation="MAEPVGDLVVDLSLDAARFDEQMARVRRHFSGTETDAKKTAAVV
                     EQSLSRQALAAQKAGISVGQYKAAMRMLPAQFTDVATQLAGGQSPWLILLQQGGQVKD
                     SFGGMIPMFRGLAGAITLPMVGATSLAVATGALAYAWYQGNSTLSDFNKTLVLSGNQA
                     GLTADRMLVLSRAGQAAGLTFNQTSESLTALVNAGVRGGEQFEAISQSVARFSSASGV
                     EVDKVAEAFGKLTTDPTSGLTAMARQFHNVTAEQIAYVAQLQRSGDEAGALQAANEAA
                     TKGFDDQTRRLKENMGTLETWADRTARAFKSMWDSVLDIGRPDTAQGMLEKAEKAFDE
                     ADKKWQWYQSRSHRRGKTSAFLANLRGAWEDRANAQLGLSAATLQADLEKAREMAAKD
                     WAESEASRLKYTEEAQKAYERLQTPLEKYTARQEELNKALKDGKILQADYNTLMAAAK
                     KDYEATLKKPKQSGVKVSAGDRQEDSAHAALLTLQAELRTLEKHAGANEKISQQRRDL
                     WKAESQFAVLEEAAQRRQLSAQEKSLLAHKDETLEYKRQLAALGDKVTYQERLNALAQ
                     QADKFAQQQRAKRAAIDAKSRGLTDRQAEREATEQRLKEQYGDNPLALNNVMSEQKKT
                     WAAEDQLRGSWMAGLKSGWSEWEESATDSMSQVKSAATQTFDGIAQNMAAMLTGSEQN
                     WRSFTRSVLSMMTEILLKQAMVGIVGSIGSAIGGAVGGGASASGGTAIQAAAAKFHFA
                     TGGFTGTGGKYEPAGIVHRGEFVFTKEATSRIGVGNLYRLMRGYATGGYVGTPGSMAD
                     SRSQASGTFEQNNHVVINNDGTNGQIGPAALKAVYDMARKGARDEIQTQMRDGGLFSG
                     GGR"
     gene            14135..14464
                     /locus_tag="RHX21_002734"
     CDS             14135..14464
                     /locus_tag="RHX21_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV1987895.1"
                     /translation="MKTFRWKVKPGMDVASVPSVRKVRFGDGYSQRAPAGLNANLKTY
                     SVTLSVPREEATVLESFLEEHGGWKSFLWTPPYEWRQIKVTCAKWSSRVSMLRVEFSA
                     EFEQVVN"
     gene            14464..15162
                     /locus_tag="RHX21_002735"
     CDS             14464..15162
                     /locus_tag="RHX21_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HDV1987896.1"
                     /translation="MQDIRQETLNECTRAEQSASVVLWEIDLTEVGGERYFFCNEQNE
                     KGEPVTWQGRQYQPYPIQGSGFELNGKGTSTRPTLTVSNLYGMVTGMAEDMQSLVGGT
                     VVRRKVYARFLDAVNFVNGNSDADPEQEVISRWRIEQCSELSAVSASFVLSTPTETDG
                     AVFPGRIMLANTCTWTYRGDECGYHGPAVADEYDQPTSDITKDKCSKCLSGCKFRNNV
                     GNFGGFLSINKLSQ"
     gene            15168..15911
                     /locus_tag="RHX21_002736"
     CDS             15168..15911
                     /locus_tag="RHX21_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV1987897.1"
                     /translation="MTETESAILAHARRCAPAESCGFVVRTPEGERYFPCVNISGEPE
                     AYFRMSPEDWLRAEMQGEIVALVHSHPGGLPWLSETDRRLQVQSDLPWWLVCRGAIHK
                     FRCVPHLSGRRFEHGVTDCYTLFRDAYHLAGIEMPDFHREDDWWRHGQNLYLDNLEAT
                     GLYQVPLSSAQPGDVLLCCFGSSVPNHAAIYCGDSELLHHIPEQLSKRERYTDKWQRR
                     THSLWRHREWHASAFTGICNDLAAASTFV"
     gene            15848..16480
                     /locus_tag="RHX21_002737"
     CDS             15848..16480
                     /locus_tag="RHX21_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="HDV1987898.1"
                     /translation="MARICLYGDLQRFGRRIDLRVKTGAEAIRALATQLPAFRQKLSD
                     GWYQVRIAGRDVSTSGLTAQLHETLPDGAVIHIVPRVAGAKSGGVFQIVLGAAAIAGS
                     FFTAGATLAAWGAAIGAGGMTGILFSLGASMVLGGVAQMLAPKARTPRTQTTDNGKQN
                     TYFSSLDNMVAQGNVLPVLYGEMRVGSRVVSQEISTADEGDGGQVVVIGR"
     gene            16540..20037
                     /locus_tag="RHX21_002738"
     CDS             16540..20037
                     /locus_tag="RHX21_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="HDV1987899.1"
                     /translation="MGKGSSKGHTPREAKDNLKSTQLLSVIDAISEGPIEGPVDGLKS
                     VLLNSTPVLDSEGNTNISGVTVVFRAGEQEQTPPEGFESSGSETVLGTEVKYDTPITR
                     TITSANIDRLRFTFGVQALVETTSKGDRNPSEVRLLVQIQRNGGWVTEKDITIKGKTT
                     SQYLASVVVGSLPPRPFNIRMRRMTPDSTTDQLQNKTLWSSYTEIIDVKQCYPNTALV
                     GVQVDSEQFGSQQVSRNYHLRGRILQVPSNYNPQTRQYSGIWDGTFKPAYSNNPAWCL
                     WDMLTHPRYGMGKRLGAADVDKWALYVIGQYCDQSVPDGFGGTEPRITCNAYLTTQRK
                     AWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDKVWTYNRSNVVMPDDGAPFRYSFSAL
                     KDRHNAVEVNWIDPNNGWETATELVEDTQAIARYGRNVTKMDAFGCTSRGQAHRAGLW
                     LIKTELLETQTVDFSVGAEGLRHVPGDVIEICDDDYAGISIGGRVLAVNSQTRTLTLD
                     REITLPSSGTTLISLVDGSGNPVSVEVQSVTDGVKVKVSRVPDGVAGYSVWGLKQPTL
                     RQRLFRCVSIRENDDGTYAITAVQHVPEKEAIVDNGAHFDGDQSGTVNGVTPPAVQHL
                     TAEVTADSGEYQVLARWDTPKVVKGVSFLLRLTVTADDGSERLVSTARTTETTYRFTQ
                     LALGNYRLTVRAVNAWGQQGDPASVSFRIAAPAAPSRIELTPGYFQITATPHLAVYDP
                     TVQFEFWFSEKRIADIRQVETSARYLGTALYWIAASINIKPGHDYYFYVRSVNTVGKS
                     AFVEAVGQPSDDASGYLDFFKGEIGKTHLAQELWTQIDNGQLAPDLTEIRTSITDVSN
                     EITQTVNKKLEDQSAAIQQIQKVQVDTNNNLNSMWAVKLQQMQDGRLYIAGIGAGIEN
                     TPDGMQSQVLLAADRIAMINPANGNTKPMFVGQGDQIFMNEVFLKRLTAPTITSGGNP
                     PAFSLTSDGRLTAKNADISGSVNANSGTLNNVTINQNCTIKGMLEATQVRGDFVKAVS
                     KAFPKKVGTWGNTETPNGTVTVTISDDHNFDRQIIIPPIIFNGIAYDDPGSGNNPGGT
                     RYTGYGFEVRKNGVLIASRETKGAIPGSYSAVIDMPSGRGSVTLEFKIFQKGNQGAGN
                     ITDCTVIVTKKAASGISIR"
     gene            20108..20707
                     /locus_tag="RHX21_002739"
     CDS             20108..20707
                     /locus_tag="RHX21_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ail/Lom family protein"
                     /protein_id="HDV1987900.1"
                     /translation="MRKVCAAILSAAICLAVSGAPAWASEHQSTLSAGYLHASTNVPG
                     SDDLNGINVKYRYEFTDTLGLVTSFSYAGDKNRQLTRYSDTRWHEDSVRNRWFSVMAG
                     PSVRVNEWFSAYAMAGVAYSRVSTFSGDYLRVTDNKGKKHDVLTGSDDGRHSNTSLAW
                     GAGVQFNPTESVAIDIAYEGSGSGDWRTDGFIVGVGYKF"
     gene            20772..23732
                     /locus_tag="RHX21_002740"
     CDS             20772..23732
                     /locus_tag="RHX21_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV1987901.1"
                     /translation="MAVKISGVLKDGTGKPVQNCTIQLKAKRNSTTVVVNTLASENPD
                     EAGRYSMDVEYGQYSVILLVEGFPPSHAGTITVYEDSRPGTLNDFLGAMTEDDARPEA
                     LRRFELMVEEVARNASAVAQNTAAAKKSASDASTSAREAATHATDAAGSARAASTSAG
                     QAASSAQSASSSAGTASTKATEASKSAAAAESSKSAAATSAGAAKTSETNAAASQKSA
                     ATSASTATTKASEAATSARDAAASKEAAKSSETNASTSASSAASSATAAGNSVKAAKT
                     SETNARSSETAAEQSASAAADSETAAASSAREASIKAEEAAVSATAAGKSAESAASSA
                     STATTKAGEATEQASAAARSASAAKTSETNAKASETSAESSKTAAASSASSAASSASS
                     ASASKDEATRQASAARGSATTASTKATEAAGSAAAAAQSKSTAESAATRAETAAKRAE
                     DIASAVALEDASTTKKGIVQLSSATNSTSESQAATPKAVKAAYDLANGKYTAQDATTA
                     QKGIVQLSSATNSTSESQAATPKAVKAAYDLANGKYTAQDATTAQKGIVQLSSATNST
                     SETLAATPKAVKAANDNANGRVPSARKVNGKALSADITLTPKDIGTLNSTTMSFSGGA
                     GWFKLATVTMPQASSVVSITLIGGAGFNVGSPQQAGISELVLRAGNGNPKGITGALWQ
                     RTSTGFTNFAWVNTSGDTYDIYVAIGNYATGVNIQWDYTSNASVTIHTSPAYSANKPE
                     GLTDGTVYSLYTPSEQFYPPGAPIPWPSDTVPSGYALMQGQTFDKSAYPKLAAAYPSG
                     VIPDMRGWTIKGKPASGRAVLSQEQDGIKSHTHSASASSTDLGTKTTSSFDYGTKSTN
                     NTGAHTHSLSGSTNAAGNHSHRDGRRFNPSVFKDTYQYGYTSSGQNTWGVQGSVGMST
                     GWLANTSTDGNHSHSLSGTAASAGAHAHTVGIGAHTHSVAIGSHGHTITVNAAGNAEN
                     TVKNIAFNYIVRLA"
     gene            23732..24307
                     /locus_tag="RHX21_002741"
     CDS             23732..24307
                     /locus_tag="RHX21_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HDV1987902.1"
                     /translation="MAFRMSEQPRTIKIYNLLAGTNEFIGEGDAYIPPHTGLPANSTD
                     IAPPDIPAGFVAVFNSDKASWHLVEDHRGKTVYDVASGDALFISELGPLPENVTWLSP
                     EGEFQKWNGTAWVKDAEAEKLFRIREAEETKNSLMQVASEHIAPLQDAVDLEIATEEE
                     TSLLEAWKKYRVLLNRVDTSTAQDIEWPALP"
     gene            complement(24405..24995)
                     /locus_tag="RHX21_002742"
     CDS             complement(24405..24995)
                     /locus_tag="RHX21_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDV1987903.1"
                     /translation="MSRIFAYCRISTLDQTIENQRREIESAGFKIKPQQIIEEHISGS
                     AATSERPGFNRLLARLKCGDQLIVTKLDRLGCNAMDIRKTVEQLTETGIRVHCLALGG
                     IDLTSPTGKMMMHVISAVAEFERDLLLERTHSGIVRARGAGKRFGRPPVLNEEQKQVV
                     FERIKSGVSISAIAREFKTSRQTILRAKAKLQTPDI"
BASE COUNT         5954 a         6304 c         7621 g         5314 t
ORIGIN      
        1 gcggagtata aatgcctaaa gtaataaaac cgagcaatcc atttacgaat gtttgctggg
       61 tttctgtttt aacaacattt tctgcgccgc cacaaatttt ggctgcatca acagttttct
      121 gctgtccaat tcccgaaacg aagaaatgat gggtgatggt ttcctttggt gttactgctg
      181 tcggtttgtt tccaacagta aacgtctgtt gagcacatcc tgtaataagc attgccagag
      241 cggcagaaaa caacattttt ttcatcttat tatcctgcat tgttaaaaac ggcagaatcc
      301 tatgtgacaa caattaaacg atagttaaat ggattgatga aaattaaaac tatataggtg
      361 tacgctcaga ctattggagg aagttggggg cactcagaat cctgtggaat gaaataaacc
      421 gctctttctg tccattaccc ttttagctgc gctgtatcgt cgccgtattc ccgcattaac
      481 catgaccgta gcccgacggg gaattccttc tgcgtgagtg tgcgggaata atcaaaaacg
      541 atgcacaccg ggttttactg tgctgacaga cgcagggtta ccctcatagt cgcttttccg
      601 gtgcgatggt ggaagaaacc gggatgttta ttcatcatca ctttggattg atgtatatgc
      661 tctcttttct gacgttagtc tccgacggca ggcttcaatg acccaggctg agaaattccc
      721 agaccctttt tgctcaagag cgatgttaat ttgttcaatc atttggttag gaaagcggat
      781 gttgcgggtt gttgttctgc gggttctgtt cttagttgac atgaggttgc cccgtattca
      841 gtgtcgctga tttgtattgt ctgaagttgt ttttacgtta agttgatgca gatcaattaa
      901 tacgatacct gcgtcataat tgattatttg acgtggtttg atggcgtaga tgcacgttgt
      961 gatatgtaga tgataattat tatcattttt cgggtccttt ccggcgatcc gacaggttac
     1021 ggggcggcga cctcgcgggt tttcgctatt tatgaaaatt ttccggttta aggcatttcc
     1081 gttcttcttc gtcgtaactt aatgttttta tttaaaatac cccctgaaaa gaaaggaaac
     1141 gacaggtgct gaaaacgagc ttttgggcct ctgtcgtttc ctttctctgt ttttggccgt
     1201 ggaatgaaca atggaagtca acaaaaagca gctggctgac attttcggtg cgagtatccg
     1261 taccattcag aactggcagg aacagggaat gcccgttctg cgaggcggtg gcaagggtaa
     1321 tgaggtgctt tatgactctg ccgccgttat aagatggtat gccgaaaggg atgctgaaat
     1381 tgagaacgaa aagctgtgcc gggaagttga agaactgcgg caggccagcg agacagatct
     1441 ccagccaggg actattgagt acgaacgcca tcgacttacg cgtgcgcagg ccgacgcaca
     1501 ggagctgaaa aatgccagag actccgctga agtggtggaa accgcattct gtactttcgt
     1561 gctgtcgcgg atcgcaggtg aaattgccag tattctcgac gggatccccc tgtcggtgca
     1621 gcggcgtttt ccggaactgg aaaaccgaca tgttgatttc ctgaaacggg atatcatcaa
     1681 agccatgaac aaagcagccg cgctggatga actgataccg gggttgctga gtgaatatat
     1741 cgaacagtca ggttaacagg ctgcggcatt ttgtccgcgc cgggcttcgc tcactgttca
     1801 ggccggagcc acagaccgcc gttgaatggg cggatgctaa ttactatctc ccgaaagaat
     1861 ccgcatacca ggaagggcgc tgggaaacac tgccctttca gcgggccatc atgaatgcga
     1921 tgggcagcga ctacatccgt gaggtgaatg tggtgaagtc tgcccgtgtc ggttattcca
     1981 aaatgctgct gggtgtttat gcctacttta tagagcataa gcagcgcaac acacttatct
     2041 ggttgccgac ggatggtgat gccgagaact ttatgaaaac ccacgttgag ccgaccatcc
     2101 gcgatattcc gtcgctgctg gcgctggctc cgtggtatgg caaaaagcac cgggataaca
     2161 cgctcactat gaagcgtttt tccaatggtc gtggcttctg gtgcctgggc ggtaaagcgg
     2221 caaaaaacta ccgtgaaaag tcggtggatg tggcgggtta tgatgaactt gctgcctttg
     2281 atgaggatat tgaacaggaa ggctctccga cgttccttgg cgacaaacgt attgaaggct
     2341 cggtctggcc aaagtccatc cgtggctcca cgcccaaagt gagaggcacc tgccagattg
     2401 agcgtgcagc cagtgaatcc ccgcatttta tgcgttttca tgttgcctgc ccgcactgcg
     2461 gggaggagca gtatcttaaa tttggcgaca aagagacgcc gtttggcctc aaatggacgc
     2521 cggatgaccc ctccagcgtg ttttatctct gcgagcataa tgcctgcgtc atccgccagc
     2581 aggagctgga ctttactgat gcccgttata tctgcgaaaa gaccgggatc tggacccgtg
     2641 atggcattct ctggttttcg tcatccggtg aagagattga gccacctgac agtgtgacct
     2701 ttcacatctg gacagcgtac agcccgttca ccacctgggt gcagattgtc aaagactgga
     2761 tgaaaacgaa aggggatacg ggaaaacgta aaaccttcgt gaacaccacg ctcggtgaga
     2821 cgtgggaggc gaaaattggc gaacgtccgg atgctgaagt gatggcggag cggaaagagc
     2881 attattcagc gcccgttcct gaccgtgtgg cttacctgac cgccggtatc gactcccagc
     2941 tggatcgcta cgaaatgcgc gtatggggat gggggccggg tgaggaaagc tggctgattg
     3001 atcggcagat tattatgggc cgccacgacg atgaacagac gctgctgcgt gtggatgagg
     3061 ccatcaataa aacctatacc cgccggaatg gtgcagaaat gtcgatatcc cgtatctgct
     3121 gggatactgg cgggattgac ccgaccattg tgtatgaacg ctcgaaaaag catgggctgt
     3181 tccgggtgat ccccattaaa ggggcatccg tctacggtaa gccggtggcc agcatgcctc
     3241 gtaagcgaaa caaaaacggg gtttacctta ccgaaatcgg tacggatacc gcgaaagagc
     3301 agatttataa ccgcttcaca ctgacgccgg aaggggatga accgcttccc ggtgccgttc
     3361 acttcccgaa taacccggat atttttgatc tgaccgaagc gcagcagctg acggctgaag
     3421 agcaggtcga aaaatgggtg gatggcagga aaaaaatact gtgggacagc aaaaagcgac
     3481 gcaatgaggc gctcgactgc ttcgtttatg cgctggcggc gctgcgcatc agtatttccc
     3541 gctggcagct ggatctcagt gcactgctgg cgagcctgca ggaagaggat ggtgcagcaa
     3601 ccaacaagaa aacactggca gattacgccc gtgccttatc cggagaggat gaatgacgcg
     3661 acaggaagaa cttgccgctg cccgtgcggc actgcatgac ctgatgacag gaaaacgggt
     3721 ggcaacggta cagaaagacg gacggcgagt ggagtttacg gccacttccg tgtctgacct
     3781 gaaaaaatac attgcggagc tggaagtgca gaccggcatg acacagcgac gcaggggacc
     3841 tgcaggattt tatgtatgaa aacgtcctcc attcccaccc ttctggggcc ggacggcatg
     3901 acatcgctgc gtgaatatgc cggttatcac ggcggtggca gcggatttgg tgggcagttg
     3961 cgggcgtgga acccaccggg tgaaagtgtg gatgcagccc tgttgcccaa ctttacccgt
     4021 ggcaatgccc gcgcggacga tctggtacgc aataacggct atgccgccaa cgccatccag
     4081 ctgcatcagg atcatatcgt cgggtctttt ttccggctca gtcatcgccc aagctggcgc
     4141 tatctgggca tcggggagga agaagcccgt gccttttccc gcgaggttga agcggcatgg
     4201 aaagagtttg ccgaggatga ctgctgctgc attgacgttg agcgaaaacg cacgtttacc
     4261 atgatgattc gggaaggtgt ggccatgcac gcctttaacg gtgaactgtt cgttcaggcc
     4321 acctgggata ccagttcgtc gcggcttttc cggacacagt tccggatggt cagcccgaag
     4381 cgcatcagca acccgaacaa taccggcgac agccggaact gccgtgccgg tgtgcagatt
     4441 aatgacagcg gtgcggcgct gggatattac gtcagcgagg acgggtatcc tggctggatg
     4501 ccgcagaaat ggacatggat accccgtgat ttacccggcg ggcgtgcctc gttcattcac
     4561 gtttttgaac ccgtggagga cgggcagacc cgcggtgcaa atgtgtttta cagcgtgatg
     4621 gagcagatga agatgctcga cacgctgcag aacacgcagc tgcagagcgc cattgtgaag
     4681 gcgatgtatg ccgccaccat tgagagtgag ctggatacgc agtcagcgat ggattttatt
     4741 ctgggcgcga acagtcagga gcagcgggaa aggctgaccg gctggattgg tgaaattgcc
     4801 gcgtattacg ccgcagcacc ggtccgtctg ggaggcgcaa aagtgccgca cctgatgccg
     4861 ggggactcac tgaacctgca gacggctcag gacacggata acggctactc cgtgtttgaa
     4921 cagtcactgt tgcggtatat cgctgccggg ctgggtgtct cgtatgagca gctttcccgg
     4981 aattacgccc agatgagcta ctccacggca cgggccagtg cgaacgagtc gtgggcgtac
     5041 tttatggggc ggcgaaaatt cgtcgcatcc cgtcaggcga gccagatgtt tctgtgctgg
     5101 ctggaagagg ccatcgttcg ccgcgtggtg acgttacctt caaaagcgcg tttcagcttt
     5161 caggaagccc gcagcgcctg ggggaactgt gactggatag gctccggtcg tatggccatc
     5221 gatggtctga aagaagtaca ggaagcggtg atgctgatag aagccggact gagtacctac
     5281 gagaaagagt gcgcaaaacg cggtgacgac tatcaggaaa tttttgccca gcaggtccgt
     5341 gaaacgatgg agcgccgtgc agccggtctt aaaccgcccg cctgggcggc tgcggcattt
     5401 gaatccggac tgcgacaatc aacagaggag gagaagagtg acagcagagc tgcgtaatct
     5461 cccgcatatt gccagcatgg cctttaatga gccgctgatg cttgaacccg cctatgcgcg
     5521 ggttttcttt tgtgcgcttg caggccagct tgggatcagt cgcctgacgg atgcagtatc
     5581 cggcgacagc ctgactgccg gagaggcacc cgcggcgctg gcgttatccg gtgatgatga
     5641 cggaccacga caggcccgca gttatcaggt catgaacggc atcgccgtgc tgccggtgtc
     5701 cggcacgctg gtcagccgga cgcgagcgct gcagccgtat tcggggatga ccggttacaa
     5761 cggcattatc gcccgtctgc aacaggctgc cagcgacccg atggtggacg gcattctgct
     5821 cgatatggat acgccaggcg ggatggtggc aggggcattt gactgcgctg acatcatcgc
     5881 ccgtgtgcgt gacataaagc cggtatgggc gctggccaac gacatgaact gcagtgcagg
     5941 tcagttgctt gccagcgccg cctcccgacg tctggtcacg cagaccgccc ggacaggctc
     6001 catcggcgtc atgatggctc acagtaatta cggtgctgcg ctggagaaac agggcgtgga
     6061 aatcacgctg atttacagcg gcagccataa ggtggatggc aacccctaca gccatctacc
     6121 gggtgatgtc cgggagacac tgcagtcccg gatggatgca acccgccgga tgtttgcgca
     6181 gaaggtgtcg gcatataccg gcctgtccgt gcaggctgtg ctggataccg aggctgcagt
     6241 gtacagcggt caggaggcca ttgatgccgg actggctgat gaacttgtca acagcaccga
     6301 tgcgatcact gttatgcgtg atgcactgga tgcacgtaaa tcccgtctct caggagggcg
     6361 aatgaccaaa gagactcaat caacaactgt ttcagccact gcttcgcagg ctgacgttac
     6421 tgacgtggtg caagcgacgg agggcgaaaa cgccagcgcg gcgcagccgg acgtgaacgc
     6481 gcagatcacc gctgcggttg cggcagaaaa cagccgcatt atggggatcc tcaactgtga
     6541 ggaagctcac ggacgcgaag aacaggcacg tgtgctggcc gaaacccccg gtatgaccgt
     6601 ggaaacggcc cgccgcattc tggcagctgc accacagagt gcacaggcgc gcagtgacac
     6661 tgcgctggat cgtctgatgc agggggcacc ggcaccactg gctgcaggta acccggcatc
     6721 tgatgccgtt aacgatttgc tgaacacacc agtgtaaggg atgtttatga cgagcaaaga
     6781 aacctttacc cattaccagc cgctgggcaa cagtgacccg gcacatacgg caaccgcgcc
     6841 cggcggattg agtgcgaaag cgcctgcaat gaccccgctg atgctggaca cctccacccg
     6901 taagctggtt gcgtgggatg gcaccaccga cggtactgcc gttggcattc tggcggttga
     6961 tgctgaccag accagcacca cgctgacgtt ctacaagtcc ggcacgttcc gttatgagga
     7021 tgtgctctgg ccggaggctg ccagcgacga gacgaaaaaa cggaccgcgt ttgccggaac
     7081 ggcaatcagc atcgtttaac cttacccttc atcactaaag gccgcctgtg cggctttttt
     7141 tacgggattt ttttatgtcg atgtacacaa ccgcccagct gctggcggca aatgagcaga
     7201 aatttaagtt tgatccgctg tttctgcgtc tctttttccg tgagagctat cccttcacca
     7261 cggagaaagt ctatctctca caaattccgg gactggtaaa catggcgctg tacgtttcgc
     7321 cgattgtttc cggtgaggtt atccgttccc gtggcggctc cacctctgaa tttacgccgg
     7381 gatatgtcaa acccaagcat gaggtgaatc cgcagatgac cctgcgtcgc ctgccggatg
     7441 aagatccgca gaatctggcg gacccggctt accgccgccg tcgcatcatc ctgcagaaca
     7501 tgcgagacga agagctggcc attgctcagg tcgaagagat gcaggccgtt tctgctgtgc
     7561 ttaagggcaa atacaccatg accggtgaag ccttcgatcc ggttgaggtg gatatgggcc
     7621 gcagtgcggc gaacaacatc acacagtccg gtggtacgga gtggagcaag cgtgacaagt
     7681 ccacgtatga cccgaccgac gatatcgaag cctatgcgct gaacgccagc ggcgtggtga
     7741 atatcatcgt gtttgatccg aaaggctggg cgctgttccg ttccttcaaa gccgtcaagg
     7801 agaagctgga tacccgtcgc ggctctcatt ccgagctgga gacagcggta aaagacctgg
     7861 gcgaagcggt gtcctataag gggatgtatg gcgatacggc gatcgtcgtg tattccggac
     7921 agtacgtgga aaacgacgtc aaaaagaact tcctgccgga caacacgatg gtgctgggga
     7981 acactcaggc acgcggtctg cgcacctatg gctgcattca ggatgcggac gcacagcgcg
     8041 aaggtattaa cgcctctgcc cgctacccga aaaactgggt gaccaccggc gatccggcgc
     8101 gtgagttcac catgattcag tcagcaccgc tgatgctgct ggctgatcct gatgcgttcg
     8161 tgtccgtaca actggcgtaa tcatggccct tcggggccat tttctctctg tggaggagtc
     8221 catgacgaaa gatgaactga ttgcccgtct tcaggtgctg ggtgagcaac tgaaccgtga
     8281 tgtcagcctg acggggacga aagaagaact ggtgctccgt gtggcagagc tggaagagga
     8341 gcttgatgac acggatgacg ctgccggtca ggacacatct gtcagcccgg aaaatgcgct
     8401 gaccggacat gaaaatgagg tggtatcagc gcagccggat accgtgattg atacggctgc
     8461 tctggtcacg gtcgtggcac tggtgacgct gcatactgat gcacttcacg ccacgcggga
     8521 tgagcctgtg gcatttgtgc tgccgggaac ggcgtttcgt gtctctgccg gtgtggcagc
     8581 cgaaatgaca gaacatggcc tggccagaat gcaataacgg gaggcgctgt ggctgattcc
     8641 gataacctgt tcgatgctgc cattgcccgc gccgatgaaa cgatacgcgg gtacatggga
     8701 acgtcagcca ccatgacatc cggtgagctg tccggtgctg tgatacgtgg tgtttttgat
     8761 gaccctgaaa atatcagcta tgccggacag ggcgtgcgcg ttgaaggctc cagcccgtcc
     8821 ctgtttgtcc ggactgatga tgtgcggcag ctgcggcgtg gagacacact gaccatcggc
     8881 gaggaaaact tctgggtgga ccggatttcg ccggatgatg gcggaagctg tcatctctgg
     8941 cttgggcgtg gcgtgccgcc tgccgttaac cgtcgccgct gaaaggggga tgtatggcca
     9001 taaaaggtct tgagcaggcc gttgaaaacc tcagccgtat cagcaaaacg gcggtgcctg
     9061 gtgccgccgc aatggccatt aaccgcgttg cgtcatccgc gatatcgcag tcggcgtcac
     9121 aggttgcccg tgagacaaag gtacgccgga aactggtaaa ggaaagggcc aggctgaaaa
     9181 gggccacggt caaaaatccg caggccagaa tcagggttaa ccggggggat ttgcccgtaa
     9241 tcaagctggg taacgcgcgg gttgtccttt cccgccgcag acgtcgtaaa aaggggcagc
     9301 gttcatccct gaaaggtggc ggcagcgtgc ttgtggtggg aaaccgtcgt attcccggcg
     9361 cgtttattca gcaactgaaa aatggccgct ggcatgtcat gcagcgtgtg gccgggaaaa
     9421 accgttaccc cattgatgtg gtgaaaatcc cgatggcggt gccgctgacc acggcgttta
     9481 aacagaatat tgaacggata cggcgtgaac gtcttccgaa agagctgggc tatgcgctgc
     9541 agcatcaact gagaatggta ataaagcgat gaaacatact gaactccgtg cagccgtact
     9601 ggatgcactg gagaagcatg acaccggggc gacgtttttt gatggtcgcc ccgctgtttt
     9661 tgatgaggcg gattttccgg cagttgccgt ttatctcacc ggcgctgaat acacgggcga
     9721 agagctggac agcgatacat ggcaggcgga gctgcatatt gaagttttcc tgcctgctca
     9781 ggtgccggat tcagagctgg atgcgtggat ggagtcccgg atttatccgg tgatgagtga
     9841 tatcccggca ctgtcagatt tgatcaccag tatggtggcc agcggctatg actaccggcg
     9901 cgacgatgat gcgggcctgt ggagttcagc cgatctgact tatgtcatta cctatgaaat
     9961 gtgaggacgc tatgcctgta ccaaatccag taatgccggt gaaaggggcc gggaccaccc
    10021 tgtgggttta taaggggaac ggtgaccctt atgcgaaccc gctttcagac gttgactggt
    10081 cgcgtctggc aaaagttaaa gacctgacgc ccggcgaact gaccgctgag tcctatgacg
    10141 acagctatct cgatgatgaa gatgcagact ggactgcgac cgggcagggg cagaaatctg
    10201 ccggagatac cagcttcacg ctggcgtgga tgcccggaga gcaggggcag caggcgctgc
    10261 tggcgtggtt taatgaaggg gatacccgag cctataaaat ccgcttcccg aacggcacgg
    10321 tcgatgtgtt ccgcggctgg gtcagcagta tcggtaaggc ggtgacggcg aaggaagtga
    10381 tcacccgcac ggtgaaagtc accaacgtgg gccgtccgtc gatggcagaa gatcgcagca
    10441 cggtgacggc gacaaccggc atgactgtga cgcctgccag cacctcggtg gtgaaagggc
    10501 agagcaccac gctgaccgtg gcattccagc cggaaggcgc aaccgacaag agcttccgtg
    10561 cggtgtctgc ggataaaaca aaagccaccg tgtcggtcag tggtatgacc atcaccgtga
    10621 aaggtgttgc tgcaggcaag gtcaacattc cggtcgtatc cggtaatggt gaacttgctg
    10681 cggttgcaga aatcaccgtc accgccagtt aatccgggga gtcagcgatg ttcctgaaaa
    10741 ccgaatcatt tgaacataac ggtgtgaccg tcacgctttc tgaactgtca gccctgcagc
    10801 gaattgagca tctcgccctg atgaaacggc aggcagaaca ggcggagtca gacagcaacc
    10861 ggaagtttac tgtggaagac gccatcagaa ccggcgcgtt tctggtggcg atgtccctgt
    10921 ggcataacca tccgaagaag acaaagctgc cttccatgaa tgaagccgtt aaacagattg
    10981 agcaggaagt gcttaccacc tggcccacgg aggcaatttc tcatgctgaa aacgtggtgt
    11041 accggctgtc cggtatgtat gagtttgtgg tgaatgatgc tcctgaacag acagaggacg
    11101 ccgggcctgc agagcctgtt tctgcgggaa agtgttcgat ggtgagctga gttttgccct
    11161 gaaactggcg cgagagatgg ggcgacccga ctggcgtgcc atgcttgccg ggatgtcatc
    11221 cacggagtat gccgactggc accgctttta cagtacccat tattttcatg atgttctgct
    11281 ggatatgcac ttttccgggc tgacgtacac cgtgctcagc ctgtttttca gcgatccgga
    11341 tatgcatccg ctggatttca gtctgctgaa ccggcgtgag gctgacgaag agcctgaaga
    11401 tgatgtgctg atgcagaaag cggcagggct tgccggaggc gtccgctttg gcccggacgg
    11461 gaatgaagtt atccccgctt ccccggatgt ggcggacatg acggaggatg acgtaatgct
    11521 gatgacagta tcagaaggga tcgcaggagg agtccggtat ggctgaaccg gtaggcgatc
    11581 tggtcgttga tttaagtctg gatgcggcca gatttgacga gcagatggcc agagtcaggc
    11641 gtcatttttc cggtacggaa actgatgcga aaaaaacagc ggcagtcgtt gaacagtcgc
    11701 tgagccgaca ggcgctggct gcacagaaag cggggatttc cgtcgggcag tataaagccg
    11761 ccatgcgtat gctgcctgca cagttcaccg acgtggccac gcagcttgca ggcgggcaaa
    11821 gcccgtggct gatcctgctg caacaggggg gtcaggttaa ggactccttc ggcgggatga
    11881 tccccatgtt cagggggctt gccggtgcga tcaccctgcc gatggtgggg gccacctcgc
    11941 tggcggtggc gaccggtgcg ctggcgtatg cctggtatca gggcaactca accctgtccg
    12001 atttcaacaa aacgctggtc ctttccggca atcaggcggg actgacggca gatcgtatgc
    12061 tggtcctgtc cagagccggg caggcggcag ggctgacgtt taaccagacc agcgagtcac
    12121 tgacggcgct ggtgaatgcc ggtgtgcgtg gtggtgagca gtttgaggcg atcagccaga
    12181 gtgtggcgcg tttctcctct gcatccggcg tggaggtgga caaggtcgct gaagccttcg
    12241 ggaagctgac cacagacccg acgtcgggac tgacagcgat ggcacgtcag ttccataacg
    12301 tgacggcgga gcagattgcg tatgttgctc agttgcagcg ttccggcgat gaagccgggg
    12361 cattgcaggc ggcgaacgag gccgcaacga aagggtttga tgaccagacc cgccgcctga
    12421 aagagaacat gggcacgctg gagacctggg cagacaggac agcacgggca ttcaaatcca
    12481 tgtgggattc ggtgctggat attggtcgcc cggacactgc ccagggaatg ctggagaaag
    12541 cagaaaaggc ttttgatgag gcggacaaaa aatggcagtg gtatcagagc cggagccacc
    12601 ggcgcggtaa aacctcagca tttcttgcca atctccgggg agcatgggag gacagagcga
    12661 atgcgcaact tgggctttca gccgccacgt tgcaggccga tcttgaaaag gccagagaga
    12721 tggcagcaaa ggactgggcc gagtctgagg catcacggct gaaatatacc gaagaggcgc
    12781 agaaggctta cgaacggctg cagacgccgc tggagaaata taccgcccgt caggaagaac
    12841 tgaacaaggc actgaaagac gggaaaatcc tgcaggcgga ttacaacacg ctgatggcgg
    12901 cggcgaaaaa ggattatgaa gcgacgctga aaaagccgaa acagtccggc gtgaaggtgt
    12961 ctgcgggcga tcgtcaggaa gacagtgctc atgctgccct gctgacgctt caggctgaac
    13021 tccggacgct ggagaagcat gccggagcaa atgagaaaat cagccagcag cgccgggatt
    13081 tgtggaaggc ggagagccag tttgcggtac tggaggaggc ggcgcaacgt cgccagctgt
    13141 ctgcacagga gaaatccctg ctggcgcata aagatgagac gctggagtac aaacgccagc
    13201 tggctgcact tggcgacaag gttacgtatc aggagcgcct gaacgcgctg gcgcagcagg
    13261 cggataaatt cgcacagcag caacgggcaa aacgggccgc cattgatgcg aaaagccggg
    13321 ggctgactga ccggcaggca gaacgggaag ccacggaaca gcgcctgaag gaacagtatg
    13381 gcgataatcc gctggcgctg aataacgtca tgtcagagca gaaaaagacc tgggcggctg
    13441 aagaccagct tcgcgggagc tggatggcag gcctgaagtc cggctggagt gagtgggaag
    13501 agagcgccac ggacagtatg tcgcaggtaa aaagtgcagc cacgcagacc tttgatggta
    13561 ttgcacagaa tatggcggcg atgctgaccg gcagtgagca gaactggcgc agcttcaccc
    13621 gttccgtgct gtccatgatg acagaaattc tgcttaagca ggcaatggtg gggattgtcg
    13681 ggagtatcgg cagcgccatt ggcggggctg ttggtggcgg cgcatccgcg tcaggcggta
    13741 cagccattca ggccgctgcg gcgaaattcc attttgcaac cggaggattt acgggaaccg
    13801 gcggcaaata tgagccagcg gggattgttc accgtggtga atttgtcttc acgaaggagg
    13861 caaccagccg gattggcgtg gggaatcttt accggctgat gcgcggctat gccaccggcg
    13921 gttatgtcgg tacaccgggc agcatggcag acagccggtc gcaggcgtcc gggacgtttg
    13981 agcagaataa ccatgtggtg attaacaacg acggcacgaa cggtcagata ggtccggctg
    14041 ctctgaaggc ggtgtatgac atggcccgca agggtgcccg tgatgaaatt cagacacaga
    14101 tgcgtgatgg tggcctgttc tccggaggtg gacgatgaag accttccgct ggaaagtgaa
    14161 acccggtatg gatgtggctt cggtcccttc tgtaagaaag gtgcgctttg gtgatggcta
    14221 ttctcagcga gcgcctgccg ggctgaatgc caacctgaaa acgtacagcg tgacgctttc
    14281 tgtcccccgt gaggaggcca cggtactgga gtcgtttctg gaagagcacg ggggctggaa
    14341 atcctttctg tggacgccgc cttatgagtg gcggcagata aaggtgacct gcgcaaaatg
    14401 gtcgtcgcgg gtcagtatgt tgcgtgttga gttcagcgca gagtttgaac aggtggtgaa
    14461 ctgatgcagg atatccggca ggaaacactg aatgaatgca cccgtgcgga gcagtcggcc
    14521 agcgtggtgc tctgggaaat cgacctgaca gaggtcggtg gagaacgtta ttttttctgt
    14581 aatgagcaga acgaaaaagg tgagccggtc acctggcagg ggcgacagta tcagccgtat
    14641 cccattcagg ggagcggttt tgaactgaat ggcaaaggca ccagtacgcg ccccacgctg
    14701 acggtttcta acctgtacgg tatggtcacc gggatggcgg aagatatgca gagtctggtc
    14761 ggcggaacgg tggtccggcg taaggtttac gcccgttttc tggatgcggt gaacttcgtc
    14821 aacggaaaca gtgacgccga tccggagcag gaggtgatca gccgctggcg catcgagcag
    14881 tgcagcgaac tgagcgcggt cagtgcctct tttgtactgt ccacgccgac ggaaacggac
    14941 ggtgccgttt ttccgggacg tatcatgctg gccaacacct gcacctggac ctatcgcggt
    15001 gatgagtgcg gttatcacgg tccggcggtc gcggatgaat atgatcagcc gacgtccgat
    15061 atcacgaagg ataaatgcag caaatgcctg agcggctgta agtttcgcaa taacgtcggc
    15121 aactttggcg gcttcctttc cattaacaaa ctttcgcagt gaatcccatg acagagacag
    15181 aatcagcgat tctggcgcac gcccggcgat gtgcgccagc ggagtcgtgc ggcttcgtgg
    15241 tgagaacacc ggagggggaa agatattttc cctgcgtgaa tatctccggt gagccggagg
    15301 cgtatttccg gatgtcgccg gaggactggc tgcgggcaga gatgcagggt gagattgtgg
    15361 cgctggtcca cagccacccc ggtggtctgc cctggctgag tgagaccgac cggcggctgc
    15421 aggtgcagag tgatttgccg tggtggctgg tttgccgggg ggcgattcac aagttccgct
    15481 gtgtgccaca tctttccggg cggcgctttg agcacggggt gacggactgt tacacgctgt
    15541 tccgggatgc ttaccatctg gcggggattg agatgccgga ttttcatcgc gaggatgact
    15601 ggtggcgtca cggtcagaat ctctatctgg ataatctgga ggccacaggg ctgtatcagg
    15661 tgccgttgtc atcagcacaa ccgggcgatg tgctgctgtg ctgttttggt tcatcggtgc
    15721 cgaatcatgc cgccatttac tgtggtgaca gcgagctgct gcaccatatt cctgaacaac
    15781 tgagcaaacg agagaggtac accgacaaat ggcagcgacg cacacactcc ctctggcgtc
    15841 accgggaatg gcacgcatct gcctttacgg ggatttgcaa cgatttggcc gccgcatcga
    15901 ccttcgtgtg aaaacggggg ctgaagccat ccgcgcactg gccacacagc tcccggcgtt
    15961 tcgtcagaaa ctgagcgacg gctggtatca ggtacggatt gccgggcggg acgtcagcac
    16021 gtccgggtta acggcgcagt tacatgagac tctgcctgac ggcgctgtga ttcatattgt
    16081 tcccagagtc gccggggcca agtcaggggg cgtattccag attgttctgg gggctgccgc
    16141 cattgccgga tcattcttta ctgccggagc cacccttgca gcatgggggg cagccattgg
    16201 ggccggtggt atgaccggca tcctgttttc tctcggtgcc agtatggtgc tcggtggtgt
    16261 ggcgcagatg ctggcaccga aagccagaac tccccgtaca cagacaacgg ataacggtaa
    16321 gcagaacacc tatttctcct cactggataa catggttgcc cagggcaatg ttctgcctgt
    16381 tctgtacggg gaaatgcgcg tggggtctcg cgtggtttct caggagatca gcacggcaga
    16441 cgaaggggat ggtggtcagg ttgtggtgat tggtcgctga tgaaaaacgt ttatgtgaaa
    16501 ccgcctccgg gcggttttgt cgtttatgga gcgtgaggaa tgggtaaagg cagcagtaag
    16561 gggcatactc cgcgcgaagc gaaggacaac ctgaagtcca cgcagttgct gagtgtgatc
    16621 gatgccatca gcgaagggcc gattgaaggt ccggtggatg gattaaaaag cgtgctgctg
    16681 aacagtacgc cagtgctgga cagtgagggg aataccaaca tctccggcgt cacggtggtg
    16741 ttccgggccg gtgagcagga gcagacaccg ccggagggat ttgaatcctc cggctccgag
    16801 acggtgctgg gtacggaagt gaagtacgac acgccgatta cccggaccat cacgtcggca
    16861 aacatcgacc gtctgcgctt taccttcggt gtgcaggcac tggtggaaac cacctcaaag
    16921 ggggaccgga atccgtcgga agtccgcctg ctggttcaga tacagcgtaa tggtggctgg
    16981 gtgacggaaa aagacatcac cattaagggc aaaaccacct cgcagtatct ggcctcggtg
    17041 gtggtgggta gcctgccgcc gcgcccgttt aatatccgga tgcgcaggat gacgccggac
    17101 agcaccacag accagctgca gaacaaaacg ctctggtcgt catacaccga aatcatcgat
    17161 gtgaaacagt gctacccgaa cacggcactg gtcggcgtgc aggtggactc ggagcagttc
    17221 ggcagccagc aggtgagccg taattatcat cttcgcgggc gcattctgca ggtgccgtcg
    17281 aactataacc cgcagacgcg gcaatacagc ggtatctggg acggaacgtt taagccggca
    17341 tacagcaaca acccggcctg gtgtctgtgg gatatgctga cccacccgcg ctacggcatg
    17401 gggaaacgtc ttggtgcggc ggatgtggac aaatgggcgc tgtatgtcat cggccagtac
    17461 tgcgaccagt cagtgccgga cggctttggc ggcacggagc cgcgcatcac ctgtaatgcg
    17521 tacctgacca cacagcgcaa ggcgtgggat gtgctcagtg atttctgctc ggcgatgcgc
    17581 tgtatgccgg tatggaacgg gcagacgctg acgttcgtgc aggaccgacc gtcggataag
    17641 gtgtggacct ataaccgcag taatgtggtg atgccggatg atggcgcgcc gttccgctac
    17701 agcttcagcg ccctgaagga ccgccataat gccgttgagg tgaactggat tgacccgaac
    17761 aacggctggg agacggcgac agagcttgtt gaagatacgc aggccattgc ccgttacggt
    17821 cgtaacgtca cgaagatgga tgcctttggc tgtaccagcc gggggcaggc gcaccgcgcc
    17881 gggctgtggc tgattaaaac ggaactgctg gaaacgcaga ccgtggactt cagcgtgggt
    17941 gcggaagggc ttcgccatgt accgggggat gtcattgaaa tctgcgatga tgactatgcg
    18001 ggtatcagca tcggcgggcg cgtgctggcg gtgaacagcc agacccggac gctgacgctc
    18061 gaccgtgaaa tcacgctgcc atcctccggt accacgctga taagcctggt tgacggaagt
    18121 ggcaatccgg tcagcgtgga ggtccagtcc gtcaccgacg gcgtgaaggt aaaagtgagc
    18181 cgtgttcctg acggcgttgc cggatacagc gtgtgggggc tgaagcagcc gacgctgcgc
    18241 cagcgactgt tccgctgcgt gagtatccgt gagaacgacg acggcacgta tgccatcacc
    18301 gccgtgcagc atgtgccgga aaaagaggcc atcgtggata acggggcgca ctttgacggc
    18361 gaccagagcg gcacggtgaa tggtgtcacg ccgccagcgg tgcagcacct gactgccgaa
    18421 gtcaccgcag acagcgggga atatcaggtg ctggcgcgct gggacacacc gaaggtggtg
    18481 aagggcgtga gcttcctgct ccgtctgacc gtaacagcgg acgacggcag tgagcggctg
    18541 gtcagcacgg cccggacgac ggaaaccaca taccgcttca cacaactggc gttggggaac
    18601 tacaggctga cagtccgggc ggtaaatgcg tggggacagc agggcgatcc ggcatcggta
    18661 tcgttccgga ttgccgcacc ggcagcgccg tctcggattg agctgacacc gggctatttt
    18721 cagataaccg ccacgccgca tcttgcggtt tatgacccga cggtacagtt tgagttctgg
    18781 ttctcggaaa aacggattgc ggatatcagg caggttgaaa ccagcgcgcg ttatcttggt
    18841 acggcactgt actggatagc cgccagtatc aatatcaaac cgggccatga ttattatttt
    18901 tacgttcgca gtgtgaacac cgttggcaaa tcggcattcg tggaggctgt cggtcagccg
    18961 agtgatgatg catcaggcta tctggatttt ttcaaaggcg agatagggaa aacccatctg
    19021 gctcaggagc tgtggacgca gattgataac ggtcagcttg cgcctgacct gactgaaatc
    19081 aggacgtcca taacggatgt cagcaatgaa ataacacaga ccgtcaataa gaaactggaa
    19141 gaccagagtg cagcgatcca gcagatacag aaggttcagg ttgatacaaa taataacctg
    19201 aacagcatgt gggcagtgaa gctgcagcag atgcaggacg gacgccttta tattgcgggt
    19261 atcggtgccg gtattgagaa cacccctgac ggcatgcaga gtcaggtgct gctggcagca
    19321 gacaggattg cgatgattaa tcctgcgaat ggcaacacaa agccgatgtt tgttggtcag
    19381 ggcgatcaga tattcatgaa tgaagtgttc ctgaaacgcc tgacggcccc caccattacc
    19441 agcggcggta atcctccggc attttccctg acatcagacg ggagactgac ggcgaaaaat
    19501 gcggatatca gtggcagtgt gaatgcgaac tcaggaacgc tcaacaatgt cacgattaac
    19561 cagaactgta cgattaaggg catgctggag gcgacccagg tcagaggaga tttcgttaaa
    19621 gctgtatcaa aagccttccc gaaaaaagtc ggtacgtggg gtaacacgga aacaccaaac
    19681 ggtacggtta cagtcaccat cagcgatgat cataactttg accgccagat tattattccg
    19741 cccattattt ttaacggtat agcgtatgac gatccgggga gcggaaataa cccaggaggc
    19801 acgcgataca cgggttatgg ttttgaagtt cgcaaaaacg gcgtattaat cgcatccaga
    19861 gaaactaaag gggccattcc cggtagttac agtgcagtta ttgatatgcc gagtggcagg
    19921 ggaagcgtca ctctggagtt taagattttc cagaaaggca atcagggggc aggcaatatc
    19981 accgactgta cggtgattgt gaccaaaaaa gccgcttccg gcatcagtat tcgttgaaat
    20041 atttataacc ccaataaagg gcgtcaggaa tgacgccttt tttattgcag aaaagcgaga
    20101 ggtaattatg cgtaaagttt gtgcagcaat tttgtccgca gccatttgtc tggccgtatc
    20161 cggtgcgcct gcatgggcgt ctgaacatca gtccacgctg agcgcggggt atcttcatgc
    20221 ctcgacgaac gtccccggca gcgatgatct gaacgggatt aacgtgaaat accgttatga
    20281 gtttacggac acactggggc tggtgacgtc attcagctat gcaggagaca agaatcgcca
    20341 gctgacccgt tacagcgata cccgctggca tgaagattcc gttcgtaacc gctggttcag
    20401 cgtaatggcg gggccgtctg tgcgcgtgaa tgaatggttc agcgcgtatg cgatggcggg
    20461 tgtagcttac agccgtgtgt cgactttctc cggggattat cttcgcgtaa ctgacaacaa
    20521 ggggaaaaag cacgatgtgc tgaccggaag tgatgacggt cgccacagca acacgtctct
    20581 ggcgtggggg gctggcgtgc agtttaaccc gaccgaatcc gtggccattg atattgctta
    20641 tgaaggctcc ggcagtggtg actggcgcac tgacggtttc atcgtgggtg tcggttataa
    20701 attctgatta gccaggtaac acagtgttat gacagcccgc cggttcaggc gggctttttt
    20761 gtggggtgaa tatggcagta aagatttcag gtgtactgaa agacggcaca ggaaaaccgg
    20821 tacagaactg cacaatccag ctgaaagcaa aacgtaacag caccacggtg gtggtgaaca
    20881 cgctggcctc agaaaatccg gatgaagccg ggcgttacag catggacgtt gagtacgggc
    20941 agtacagcgt tattctgttg gtggagggat tcccgccgtc acatgccggg accatcaccg
    21001 tgtatgaaga ttcccgaccc ggtacgctga atgattttct cggtgccatg acggaggatg
    21061 atgcccgtcc tgaggcactg cgccgttttg aactgatggt ggaagaggtg gcgcgtaacg
    21121 cgtccgcggt ggcacagaac acggcagccg cgaagaagtc agccagcgat gccagcacat
    21181 cagcccgtga ggcggcaacc catgcgactg atgctgcagg ctcagcacgc gcagccagca
    21241 cgtcagccgg acaggccgcg tcgtcggctc agtcagcatc ttccagcgca ggaacggcat
    21301 caacaaaggc cactgaagca tcaaaaagtg ctgccgctgc agagtcctca aaaagcgcgg
    21361 cggccaccag tgccggtgcg gcgaaaacgt cagaaacgaa tgctgcagcg tcacaaaaat
    21421 cagcagccac ttctgcatcc actgcgacga cgaaagcgtc agaagccgcc acttcagcca
    21481 gagatgcggc ggcctccaaa gaggcggcaa aatcatcaga aacgaacgcc tccacaagcg
    21541 ccagcagtgc agcctcctcg gcaacggcgg caggaaattc cgtgaaggcg gcaaaaacgt
    21601 ccgagacgaa tgccaggtct tctgaaacgg cagcggaaca gagcgcctca gctgcggcag
    21661 actctgagac agcagctgca tcatcggccc gtgaggcgtc cattaaggca gaggaggcag
    21721 cagtcagtgc caccgccgcc ggaaaatcgg cagaaagcgc cgcatcatcc gcttcaacag
    21781 ccacaacgaa ggctggcgaa gccactgaac aggccagcgc agcagcgagg tctgcttccg
    21841 cagcgaagac atccgaaacg aacgcgaaag cgtcggaaac cagcgcagaa tcctcaaaaa
    21901 cggctgccgc atcgtccgcc agttcggcgg cgtcatcggc atcatctgcg tctgcttcaa
    21961 aagatgaggc gaccagacag gcgtcagcag cgaggggcag cgccacgacg gcatccacga
    22021 aggcgacaga ggctgctggc agtgcggcag cggcagcaca gagcaaaagt acggcggaat
    22081 ccgcggcaac gcgcgccgag acagcagcaa aacgggcaga ggatattgca tccgccgtgg
    22141 cgcttgagga tgcgagcacg acgaaaaagg ggatagtaca gctcagcagt gcgaccaaca
    22201 gcacttccga gtcacaggcg gcaacgccaa aagccgttaa ggccgcgtat gacctggcta
    22261 acgggaaata caccgcacag gatgcaacga cagcacagaa agggatagtt cagctcagca
    22321 gtgcgactaa cagcacttcc gagtcacagg cggcaacgcc aaaagccgtt aaggccgcgt
    22381 atgatctggc taacgggaaa tacaccgcac aggacgctac gacagcacaa aaaggaattg
    22441 tccagctcag tagtgcaacc aacagcacat ctgaaacgct tgctgcgaca ccgaaagcag
    22501 tgaaagcagc taatgacaat gcgaatggtc gggtaccttc tgcccgtaag gtgaatggta
    22561 aggcgctttc agcggatata acactgacgc cgaaagatat tggtacgctt aactcaacaa
    22621 caatgtcatt cagcggtggt gctggttggt tcaaattagc aacggtaacc atgccacagg
    22681 cgagttctgt tgtttcaatt acgttgattg gtggcgctgg atttaacgtg gggtcacctc
    22741 aacaggcagg tatatctgaa cttgttttac gtgcaggtaa tggtaatccg aaggggatta
    22801 ctggtgcttt atggcagcgc acatcgacag ggtttacaaa ttttgcctgg gtcaatacat
    22861 ctggtgatac ttacgatatt tacgttgcaa tcggaaatta tgcgactggt gtaaatattc
    22921 aatgggatta taccagtaat gccagcgtga cgattcatac gtcaccagca tattctgcta
    22981 ataagccgga agggttaacg gacggtacag tttattcact ctatacgcca tcagagcagt
    23041 tttatccgcc tggcgcacca atcccgtggc catcagatac cgttccgtct ggctatgccc
    23101 tgatgcaggg gcagactttt gacaaatctg catacccgaa acttgcagcc gcttatccgt
    23161 caggcgtgat ccctgatatg cgtggctgga cgattaaggg caaacctgcc agtggtcggg
    23221 ccgtattgtc tcaggaacag gacggcatta aatcgcatac ccacagcgcc agcgcatcca
    23281 gtacggattt ggggacgaaa accacatcgt cgtttgatta cggcactaaa tccacgaata
    23341 acactggtgc gcatacccat agtttaagtg gcagcacgaa tgcagctggt aatcacagcc
    23401 atagagatgg ccgtcgattt aaccccagtg tttttaaaga tacttatcaa tatggttata
    23461 caagctcagg tcaaaatacc tggggtgtac aaggctcagt aggtatgtct acggggtggt
    23521 tagcgaatac cagtacagat ggtaatcata gccattcact gtccggcaca gcagcatctg
    23581 caggtgcaca cgcgcatact gtcggtattg gtgctcatac gcactccgtt gcgattggtt
    23641 cacatggaca caccatcacc gttaacgctg ctggtaacgc ggaaaacacc gtcaaaaaca
    23701 tcgcatttaa ctatattgtg aggcttgcat aatggcattc agaatgagtg aacaaccacg
    23761 gaccataaaa atttataatc tgctggccgg aactaatgaa tttattggtg aaggtgacgc
    23821 atatattccg cctcatacag gtctgccagc aaacagtacc gatattgcac caccagatat
    23881 tcctgctggc tttgtggctg ttttcaacag tgataaggca tcgtggcatc tcgttgaaga
    23941 ccatcggggt aaaacggttt atgacgtagc gtcaggggac gcgttattta tttctgaact
    24001 cggtccgtta ccggaaaatg ttacctggtt atcgccggaa ggggagtttc agaagtggaa
    24061 cggcacagcc tgggtgaaag atgcagaagc agaaaaactg ttccggatcc gagaggcgga
    24121 agaaacaaaa aacagcctga tgcaggtagc cagtgagcat attgcgccac ttcaggatgc
    24181 tgtagatctg gaaatcgcaa cggaggaaga aacctcattg ctggaagcct ggaaaaagta
    24241 tcgggtgttg ctgaaccgtg ttgatacgtc aactgcacag gatattgaat ggccagcact
    24301 gccgtagggt aaaacatata aattctataa ttagatgtat ctttccattt acggcaagga
    24361 agggggcttg gaagacgtaa agcatctcac accgagatta ttttttatat gtcaggtgtc
    24421 tgaagttttg ctttggctct taaaatggtt tgccgcgagg ttttgaattc ccgggcaatg
    24481 gcacttatac ttacacctga cttaattcgt tcgaatacca cctgtttctg ttcttcattt
    24541 aacacaggtg gtcgaccaaa acgtttccct gcgccgcggg ctcttactat cccggaatga
    24601 gtgcgttcaa gtaaaaggtc tcgttcaaat tcagcgactg ctgaaattac gtgcatcatc
    24661 atttttcctg ttggactggt caggtcaatg ccccccaatg ctaagcaatg cactctgata
    24721 cctgtttcgg tcagttgttc cactgttttc ctgatatcca ttgcattaca accaaggcga
    24781 tccagttttg tcacaatcaa ttgatcacca catttcaggc gagcaagcaa ccggttaaaa
    24841 ccaggacgct cactggttgc tgctgagccg ctaatgtgtt cttcgattat ttgctgaggt
    24901 ttgattttaa aacctgcact ttcgatttcc cggcgttgat tttcgatggt ctgatccagc
    24961 gttgatatcc gacagtaagc aaaaattcga gacatagtga gactctatac gaaattggtg
    25021 ttcatatcat aatgcatctc agaaaataat tttgattatt tttgtgcata tttgtatgta
    25081 cacgttcgaa aataaacgaa tgcgtatgca accccgtaat tttggtgaga cccaaaatcg
    25141 attttgtgaa aaatggcttt aactcggttt gtttttcgag ttccgggcgg act
//
LOCUS       DAPGUL010000062        25035 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.062, whole genome shotgun sequence.
ACCESSION   DAPGUL010000062 DAPGUL010000000
VERSION     DAPGUL010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25035
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.062"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            576..1292
                     /gene="nanC"
                     /locus_tag="RHX21_002743"
     CDS             576..1292
                     /gene="nanC"
                     /locus_tag="RHX21_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313297.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminic acid outer membrane channel
                     NanC"
                     /protein_id="HDV1987904.1"
                     /translation="MKKAKILSGVLLLCFSSPLISQAATLDVRGGYRSGSHAYETRLK
                     VSEGWQNGWWASMESNTWNTIHDNKKENAALNDVQVEVNYAIKLDDQWTVRPGMLTHF
                     SSNGTRYGPYVKLSWDATKDLNFGIRYRYDWKAYRQQDLSGDMSRDNVHRWDGYVTYH
                     INSDFTFAWQTTLYSKQNDYRYANHKKWATENAFVLQYHMTPDITPYIEYDYLDRQGV
                     YNGRDNLSENSYRIGVSFKL"
     gene            1312..2418
                     /gene="nanM"
                     /locus_tag="RHX21_002744"
     CDS             1312..2418
                     /gene="nanM"
                     /locus_tag="RHX21_002744"
                     /EC_number="5.1.3.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418730.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate epimerase"
                     /protein_id="HDV1987905.1"
                     /translation="MNKTITALAIMMASFAANASVLPETPVPFKSGTGAIDNDTVYIG
                     LGSAGTAWYKLDTQAKDKKWTALAAFPGGPRDQATSAFIDGDLYVFGGIGKNSKGLTQ
                     VFNDVHKYNPKTNSWVKLMSHAPMGMAGHVTFVHNGKAYVTGGVNQNIFNGYFEDLNE
                     AGKDSTAIDKINAHYFDKKAEDYFFNKFLLSFDPSTQQWSYAGESPWYGTAGAAVVNK
                     GDKTWLINGEAKPGLRTDAVFELDFTGDNLKWNRLAPVSSPDGVAGGFAGISNDSLIF
                     AGGAGFKGSRENYQNGKNYAHEGLKKSYSTDIHLWHNGKWDKSGELSQGRAYGVSLPW
                     NNSLLIIGGESAGGKAVTDSVLISVKDNKVTVQN"
     gene            2482..3462
                     /locus_tag="RHX21_002745"
     CDS             2482..3462
                     /locus_tag="RHX21_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialate O-acetylesterase"
                     /protein_id="HDV1987906.1"
                     /translation="MNAIISPNYYYVLTVAGQSNAMAYGEGLPLPDREDAPHPRIKQL
                     ARFTHTHPGGPPCHFNDIIPLTHCPHDVQDMQGYHHPLATNHQTQYGTVGQALHIARK
                     LLPFIPDNAGILIVPCCRGGSAFTAGSEGTYSERHGASHDACRWGTDTPLYQDLVSRT
                     RAALAKNPHNKFLGVCWMQGEFDLMTSDYASHPQHFNHMVEAFRRDLKQFHSQLNNIT
                     AAPWFCGDTTWYWKENFPHAYEAIYGNYQNNVLANIIFVDFQQQGERGLTNAPDEDPD
                     DLSTGYFGSAYRSAENWTTSLRSSHFSAAARRGIISDRFVEAILQFWRER"
     gene            complement(4045..5271)
                     /locus_tag="RHX21_002746"
                     /pseudo
     CDS             complement(4045..5271)
                     /locus_tag="RHX21_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378101.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase"
     gene            5349..5648
                     /locus_tag="RHX21_002747"
     CDS             5349..5648
                     /locus_tag="RHX21_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001332034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDV1987907.1"
                     /translation="MLGVLTLARDIQLAIVNKMTQVLIGDIYLRQQCDVFWLGYTISP
                     AYTRQGYAIEAITATIDWIKENGFSLIKAGVNPENTLSKKLLIRIGFNFSSIEDG"
     gene            6025..6282
                     /locus_tag="RHX21_002748"
     CDS             6025..6282
                     /locus_tag="RHX21_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjhX family toxin"
                     /protein_id="HDV1987908.1"
                     /translation="MNLSRQEQRTLHVLAKGGRIAHVRDSSGRVTSVECYSREGLLLT
                     DCTLAVFKKLKTKKLIKSVNGQPYRINTTGLNNVRAQLDNR"
     gene            6294..6845
                     /locus_tag="RHX21_002749"
     CDS             6294..6845
                     /locus_tag="RHX21_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014837489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDV1987909.1"
                     /translation="MTAHHFTFQITDESDASDIREVETRAFGFSKEADLTASLLEDES
                     ARPALSLLARHEGKAVGHILFTRATFKGEMDSPLMHILAPLAVIPEYQGMGVGGRLIR
                     TGIEHLRLMGCQTVFVLGHATYYPRHGFEPCAGDKGYPAPYPIPEEHKACWMMQALTA
                     QPMNVTGHIQCAQALMKPEHWRE"
     gene            6897..7643
                     /locus_tag="RHX21_002750"
     CDS             6897..7643
                     /locus_tag="RHX21_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDV1987910.1"
                     /translation="MDIPRIFTISESEHRIHNPFTEEKYATLGRVLRMKPETRILDLG
                     SGSGEMLCTWARDHGITGTGIDMSSLFTAQARRRAEELGVSERVHFIHNDAAGYVANE
                     KCDVAACVGATWIAGGFAGTVELLAQSLKPGGIMLIGEPYWRQLPATDEIAQACGVSS
                     TTDFLTLPGLVSAFDDLGYDVVEMVLADQEGWDRYEAAKWLTMRRWLEANPDDDFAAE
                     VRAELNISPKRHVTYAREYFGWGVFALIAR"
     gene            7771..8031
                     /locus_tag="RHX21_002751"
     CDS             7771..8031
                     /locus_tag="RHX21_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987911.1"
                     /translation="MSQHEQFCQACGMPMSAPDAHSASDQYCAYCSDSNGNLKPWEEA
                     VSGLASFLDSWQKVGPEEAHKRAKRYLTAMPAWAHKAESDLS"
     gene            8069..8185
                     /locus_tag="RHX21_002752"
                     /pseudo
     CDS             8069..8185
                     /locus_tag="RHX21_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227376.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
     gene            8430..9551
                     /locus_tag="RHX21_002753"
     CDS             8430..9551
                     /locus_tag="RHX21_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418725.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HDV1987912.1"
                     /translation="MSFSVQETLFSLLQHNAISGHENAVADVMLCEFRRQAKEVWRDR
                     LGNVVARYGSDKPDALRLMIFAHMDEVGFMVRKIEPSGFLRFERVGGPAQVTMAGSIV
                     TLTGDKGPVMGCIGIKSYHFAKGDERTQSPSVDKLWIDIGAKDKDDAIRMGIQVGTPV
                     TLYNPPQLLANDLVCSKALDDRLGCTALLGVADAISTTELDIAVYLVASVQEEFNIRG
                     IVPVLRRVKPDLAIGIDITPSCDTPDLHDYSEVRINQGVGITCLNYHGRGTLAGLITP
                     PRLIRMLEQTALEHNIPVQREVAPGVITETGYIQVEQDGIPCASLSIPCRYTHSPAEV
                     ASLRDLTDCIRLLTALAGMSAAHFPVEPDSGTTQEAHPL"
     gene            9548..9826
                     /locus_tag="RHX21_002754"
     CDS             9548..9826
                     /locus_tag="RHX21_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDV1987913.1"
                     /translation="MKKILVACGTGMSTSTMIAHKLQEFLTEQGISATTAQCCLNEIP
                     LNCNGMDLIVTSMRTNSDYGIPTLNGAALLTGINDDALKQQIKALLTQ"
     gene            9838..11151
                     /locus_tag="RHX21_002755"
     CDS             9838..11151
                     /locus_tag="RHX21_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDV1987914.1"
                     /translation="MFDYILSLGGTVFVPIIMIVIGLIFRIPWLQAIKAGVTVGIGFV
                     GMGLVIVMAIDSLSPPIKVMIERFGLALHVFDVGAGPASGVGYATAIGAMIIPVIFLL
                     NVAMLVTRLTKTMNVDIYNYWHYAITGTVVQLMTGSLIYGVLGAICHAALSLKMADWT
                     AKRVQNIVGLEGISIPQGYGSSSVPLFVLLDAIYEKIPFMKGRNIDAQEIQKRYGMVG
                     DPVIIGVVLGLIFGLAAGEGFKGCASLMITVAAIMVLFPRMIRLIVEGLMPISDGARK
                     FFQKYFKGREVYIGLDTAVTLGHPTTIAVGLLLIPIMLILASILPGNKVLPLADLPVA
                     PFFICMATVIHRGDLVRTLISGVIVMITVLLIATQFAPYFTEMALKGGFSFAGESAQI
                     SALSVGNMFGWSISELMSLGIIGVVVAVGIVASVVLFLRKRELSE"
     gene            11164..11970
                     /gene="sgcQ"
                     /locus_tag="RHX21_002756"
     CDS             11164..11970
                     /gene="sgcQ"
                     /locus_tag="RHX21_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BtpA family protein SgcQ"
                     /protein_id="HDV1987915.1"
                     /translation="MSWLKEVIGTEKAVIAMCHLRALPGDPSFDAQLGMNWVIDKAWD
                     DLMALQNGGVDAVMFSNEFSLPYLTKVRPETTAAMARIIGQLMSDIRIPFGVNVLWDP
                     VASFDLAMATGAKFIREIFTGAYASDFGVWDTNVGETIRHQHRIGAGEVKTLFNIVPE
                     AAVYLGNRDICSIAKSTVFNNHPDALCVSGLTAGTRTDSALLKRVKETVPDTVVLANT
                     GVCLENVEEQLSIADGCVTATTFKKDGVFANFVDQARVSQFMEKVHHIRR"
     gene            12101..12532
                     /locus_tag="RHX21_002757"
     CDS             12101..12532
                     /locus_tag="RHX21_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDV1987916.1"
                     /translation="MINDIKWVQAQREATDWRQAVEIATRPLVAYGAAQPCYVNGIIE
                     NTLNWGPYYLIAPGIALPHARPEQGANYNQVSITTLRTPVAFGNEECDPVWLLLCVSA
                     TDANAHILTIQRISQFIDSPQRLAAVGNASTDDALFALVSG"
     gene            12544..13176
                     /locus_tag="RHX21_002758"
     CDS             12544..13176
                     /locus_tag="RHX21_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3 epimerase family protein"
                     /protein_id="HDV1987917.1"
                     /translation="MILHPSLASANPLHYGRELTALDNLDFGSLHLDIEDSSFINNIT
                     FGMKTVQAVARQTPHPLSFHFMVARPQRWFNALAEIRPAWIFVHAETLDYPSETLTEI
                     RHTGARAGLVFNPATPIDAWRYLASELDGVMVMTSEPDGQGQRFIPSMCEKIQKVRTA
                     FPQTECWADGGITLAAAQQLAAAGAQHMVIGRALFSSSDYRATLAQFATL"
     gene            13193..13975
                     /locus_tag="RHX21_002759"
     CDS             13193..13975
                     /locus_tag="RHX21_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDV1987918.1"
                     /translation="MSQQRPDRIKQMLHYLWQHRHLSTQQAMELFGYAEATVRRDFQY
                     IANQYPGMIRGHGCLDFDDSTDDKEYVFDVKRTLQSVAKREIAALARTMIKDGDCFFL
                     DSGSTCLELAKCLADARVKVICNDIKIANELGCFPHVESYIIGGLIRPGYFSVGESLA
                     LEMINAFSVERAFISCDALSLETGITNATMFEVGVKTRIIQRSREVILMADHSKFDAV
                     EPHAVATLSCIKTIISDSGLPETIAQRYQRAGCQLFLPHSIK"
     gene            14278..15066
                     /locus_tag="RHX21_002760"
     CDS             14278..15066
                     /locus_tag="RHX21_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDV1987919.1"
                     /translation="MVRKGCNSLVRAEKILTHIAWVGMASYMELLNKFQYPKSSLLNL
                     LNVMVECGFLIKNKNGYYSLGIKNYELGCQALHRQNIFEVTKRPMQELSLKSGLVCHL
                     GAMESISAIYLDKIESPDSVPTSKSWIGKKLELHITALGKALLAWKTREELDYFLEAL
                     TLTPHTRNTFTDKKLFLEELQKTRLRGWAIDNEESTYGAVCLSMPVFNMYNRVNYAIS
                     LSGDPVVYSGNKIDSYLELLRKCAEQISYGLGYRNENEHLRKGN"
     gene            15071..15976
                     /locus_tag="RHX21_002761"
     CDS             15071..15976
                     /locus_tag="RHX21_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418718.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HDV1987920.1"
                     /translation="MKKFSGIIPPVSSTFHRDGTLDKKAMREVADFLINKGVDGLFYL
                     GTGGEFSQMNTAQRMALAEEAVTIVDGRVPVLIGVGSPSTDEAVKLAQHAQAYGADGI
                     VAINPYYWKVAPRNLDDYYQQIARSVTLPVILYNFPDLTGQDLTPETVTRLALQNENI
                     VGIKDTIDSVGHLRTMINTVKSVRPSFSVFCGYDDHLLNTMLLGGDGAITASANFAPE
                     LSVGIYRAWREGDLATAATLNKKLLQLPAIYALETPFVSLIKYSMQCVGLPVETYCLP
                     PILEASEEAKDKVHVLLTAQGILPV"
     gene            15987..17954
                     /gene="yjhG"
                     /locus_tag="RHX21_002762"
     CDS             15987..17954
                     /gene="yjhG"
                     /locus_tag="RHX21_002762"
                     /EC_number="4.2.1.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylonate dehydratase YjhG"
                     /protein_id="HDV1987921.1"
                     /translation="MSVRNIFADESHDIYTVRTHADGPDGELPLTAEMLINRPSGDLF
                     GMTMNAGMGWSPDELDRDGILLLSTLGGLRGADGKPVALALHQGHYELDIQIKAAAEV
                     IKANHALPYAVYVSDPCDGRTQGTTGMFDSLPYRNDASMVMRRLIRSLPDAKAVIGVA
                     SCDKGLPATMMALAAQHNIATVLVPGGATLPAKDGEDNGKVQTIGARFANGELSLQDA
                     RRAGCKACASSGGGCQFLGTAGTSQVVAEGLGLAIPHSALAPSGEPVWREIARASARA
                     ALNLSQKGITTREILTDKAIENAMTVHAAFGGSTNLLLHIPAIAHQAGCHIPTVDDWI
                     RINKRVPRLVSVLPNGPVYHPTVNAFMAGGVPEVMLHLRSLGLLHEDVMTVTGSTLKE
                     NLDWWEHSERRQRFKQLLLDQEQINADEVIMSPQQAKARGLTSTITFPVGNIAPEGSV
                     IKSTAIDPSMIDEQGIYYHKGVAKVYLSEKSAIYDIKHDKIKAGDILVIIGVGPSGTG
                     MEETYQVTSALKHLSYGKHVSLITDARFSGVSTGACIGHVGPEALAGGPIGKLRTGDV
                     IEIKIDCRELHGEVNFLGTRSDEQLPSQEEATAILNARPSHQDLLPDPELPDDTQLWA
                     MLQAVSGGTWTGCIYDVNKIGAALRDFMNKN"
     gene            18061..19410
                     /locus_tag="RHX21_002763"
     CDS             18061..19410
                     /locus_tag="RHX21_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntP family permease"
                     /protein_id="HDV1987922.1"
                     /translation="MPLIIVVAGIALLLLLTIKIKLNTFVSLIIVSIAVAIASGMDLS
                     KVVTSVESGLGGTLGHIGLIFGFGVMLGRLLADAGGAQRIALTMLNYFGKNKLDWAVV
                     CSAFIVGIALFFEVGLILLVPILFAIAREAKISPMFMCVPMLSGLLVAHGFLPPHPGP
                     TVIAREYGADVGLVLIYGIIVGIPTFILCGPVLNKFCQRIIPDAFKKEGNIASLGATR
                     RFSESEMPGFGISFLTAMLPVILMAVVTIIQMTHAKSAADSGLFYNVILFLGNSTIAM
                     LISLLFAIYTMGLGRGKTIPDLMDSCGKAIAGIAGLLLIIGGGGAFKQVLIDSGVGQY
                     ISTLVSGMDINPILMAWGVAAFLRICLGSATVAAISTAGLVIPLLAVHPNTNLALITL
                     ATGAGSCICSHVNDASFWMIKDFFGLTTKETLLSWTLMSTLLSISGLIFILLASLVL"
     gene            19757..20743
                     /locus_tag="RHX21_002764"
     CDS             19757..20743
                     /locus_tag="RHX21_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418715.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HDV1987923.1"
                     /translation="MDRDQTNSSLFNDDPVLHATWLYYQEGKSQTEVAAIMGVSRVTV
                     VKYLQTARENGLVHINLDVNVFGSIDAALQIRDKFNLQRVIIVPDGEHAGKRDDTKLM
                     RTRLSRAGGMYLNQVIENGDVLGVAWGRTIHQMSKTMTPKSCKNVTVIQMLGSMPSQP
                     DLTIIESSSQIAYKLSGRVASLHVPAVVSSARLAMELQAEPIIRSNFDVLTRCTKAFF
                     VVGNALDENPLIRVGVLNKKEMQTYRDLGAVGVICGRFYDKEGMPVVADVDQRILGIS
                     LAQLRQIERKIFLAGGERGYDATLGALLGGYVTDLIVDEGTAEFLLACELPH"
     gene            complement(20784..21788)
                     /locus_tag="RHX21_002765"
     CDS             complement(20784..21788)
                     /locus_tag="RHX21_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001622580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug DMT transporter permease"
                     /protein_id="HDV1987924.1"
                     /translation="MFIVESYAVAIIMCFITMICWGSWANTTKLVSNKKWEFPLFYWD
                     YSIGLLLCSLLFAFTLGSMGEAGRSFIPDIQQASSSSLMSAILAGIIFNISNILLVAS
                     INLAGMAVAFPVGVGLALALGVITTYIGNPQGDPLILFLGVACVVIAIIFTAIAYGRV
                     TQEADKSRRNKGLITAILAGIIMGWFFRFLADSMSDNFSQPASGLMTPYSALVLFAVG
                     LFLSNFVLNTLVMKKPISGEPVNGKMYFSGSLRDHVCGWLGGMIWCVGLAFSLIASGQ
                     AGYAISYGLGQGATMIAVIWGVFIWREFASAPAGTNKLLLTMFISYIVGIVLIIAANQ
                     "
     gene            complement(21892..22533)
                     /locus_tag="RHX21_002766"
     CDS             complement(21892..22533)
                     /locus_tag="RHX21_002766"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000439687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HDV1987925.1"
                     /translation="MERIKLAEKIISTCREMNASGLNQGTSGNVSARYTGGMLITPSG
                     IAYSKMTPDMIVFVDDKGIPEAGKIPSSEWLFHLACYKARPELNAVIHTHAVNSTAVA
                     IHNHSIPAIHYMVAVSGTDHIPCIPYYTFGSPELADGVSKGIRESKSLLMQHHGMLAM
                     DVTLEKTLWLAGETETLADLYIKCGGLHHDVPVLSEAEMTIVLEKFKTYGLKA"
     gene            complement(22564..23679)
                     /gene="mtnA"
                     /locus_tag="RHX21_002767"
     CDS             complement(22564..23679)
                     /gene="mtnA"
                     /locus_tag="RHX21_002767"
                     /EC_number="5.3.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-methyl-5-thioribose-1-phosphate isomerase"
                     /protein_id="HDV1987926.1"
                     /translation="MNIKGKHYRTVWVSGDGKAVEIIDQTKLPFKFEVVALTSAEMAA
                     TAIQEMWVRGAPLIGVVAAYGIALGMNHDASDMGLQRYYDLLIKTRPTAINLKWALDR
                     MIDTLKDLCVSERKDVAWALAAEIAEEDVALCEQIGLHGTEVIREIAQKKPAGSVVNI
                     LTHCNAGWLATVDWGTALSPIYKAHENGIPVHVWVDETRPRNQGGLTAFELGSHGIPH
                     TLIADNAGGHLMQHGDVDLCIVGTDRTTARGDVCNKIGTYLKALAAHDNHVPFYVALP
                     SPTIDWTIEDGKSIPIEQRDGKEQSHVYGINPQGELSWVNTAPEGTRCGNYAFDVTPA
                     RYITGFITERGVCAASKSALADMFADLKSKALQGEQH"
     gene            complement(23689..24948)
                     /locus_tag="RHX21_002768"
     CDS             complement(23689..24948)
                     /locus_tag="RHX21_002768"
                     /EC_number="2.7.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000132329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-methyl-5-thioribose kinase"
                     /protein_id="HDV1987927.1"
                     /translation="MTDSIPSGYKPLTCDTLPGYLSSRLTPSCEPGGLPEEWKVSEVG
                     DGNLNMVFIVEGTHKTIIVKQALPWLRAGGEGWPLSLSRAGFEYNVLCQEAKYAGHTL
                     IPQVYFYDPEMALFAMEYLTPHVILRKELINGKKFPKLAEDIGRFLAQTLFNTSDIGM
                     SAEQKKALTAEFALNHELCKITEDLIFTEPYYNAERNNWTSPELDDAVHKAWADVEMI
                     QVAMRYKYKFMTEAQALLHGDLHSGSIMVTDTDTKVIDPEFGFMGPMAFDIGNYIGNL
                     LLAYFSRPGWDANEQRRADYQEWLLQQIVQTWSVFTREFRQLWDNKTQGDAWPTEMYQ
                     QNRAALEDAQDQFFATLLEDSLVNAGMEMNRRIIGFAGVAELKQIENTELRAGCERRA
                     LTMARDLIVNARQFKNMDSVIQSAKVK"
BASE COUNT         6423 a         6139 c         6127 g         6346 t
ORIGIN      
        1 atctttagtt tttgaagacc accgcaagtg ttcgtctggc ttcacatggc atctgcctct
       61 tagaaaaaga tcgacatatt ttgtgacacg aattgcaaat ctggttttgt tgtatggatt
      121 gcgtgatttt tgatctggta taacaggtat aaaggtgcac cacgatagtc aatgaaactg
      181 ggcatctcgc aatctatggc aaacatcact tcagttcttt ctcatcgggt gatgaaaacg
      241 cacttcagtc tgaaaggaat atgaaaatga gatcaacaga cactctattt tatgactctg
      301 ggtaaaatgg attgagtaag cgatatagct tacgaaaatt caaatcaatt aaacatcagc
      361 agagatttta tactcaggta tttaatctgg ctctctgttt atttaaataa tgtggaaaga
      421 gatttttcac aggagacatt atacaaaaaa tataaaatac agctacccgt tgccaaagac
      481 actataagcc tggcaaaaaa tattacacaa cataaatgct aattgtttat gcgggctttg
      541 tattgctttc tgtatcctac aaatgagtga aatttatgaa aaaggctaaa atactttctg
      601 gcgtattatt actgtgcttt tcgtccccat taatttctca ggctgcgaca ctggacgtac
      661 gtggtggata tcgtagtgga agccacgcct atgagactcg actcaaagtc agtgagggat
      721 ggcaaaatgg atggtgggca agcatggaaa gtaatacctg gaataccatt catgataata
      781 aaaaggaaaa tgccgcactc aatgatgttc aggttgaagt taattacgca attaaacttg
      841 atgatcaatg gacggtacgc ccgggaatgt taacgcattt tagcagcaac ggcacacgtt
      901 acggacccta cgtaaaactg tcctgggacg cgacaaaaga tcttaatttt ggcattcgct
      961 atcgttacga ctggaaagct taccgacaac aagacttatc cggtgatatg tctcgtgata
     1021 acgttcatcg ttgggatgga tatgtcactt accatattaa tagtgatttc accttcgcat
     1081 ggcaaacgac gctatacagc aaacagaacg attatcgcta tgcaaaccat aagaaatggg
     1141 cgacggaaaa tgcatttgtt ctacaatacc atatgacgcc cgatattacg ccatacatag
     1201 aatatgacta ccttgaccgt cagggtgttt acaacggcag agataattta tcggaaaaca
     1261 gttatcgcat tggtgtgtca tttaaactgt agtagacagg agacagtcac aatgaataaa
     1321 acaataacgg cgcttgctat catgatggct tcatttgccg caaacgcgtc tgtattaccg
     1381 gaaactcctg tgccatttaa aagtggtacc ggagcaattg ataacgacac tgtctacatt
     1441 ggtttaggta gcgcaggtac ggcatggtac aagctggata cacaggccaa agataaaaaa
     1501 tggacagcgt tagctgcatt ccctggtgga ccaagagatc aagcaacctc ggcatttatt
     1561 gatggtgatc tgtatgtgtt tggcggcatt ggcaaaaata gcaagggctt gactcaggta
     1621 tttaatgacg tacacaaata caaccccaaa accaatagct gggttaaatt gatgtcgcac
     1681 gcgccaatgg gcatggcggg ccatgtgact tttgtacaca acggcaaagc ttatgttact
     1741 ggcggtgtta accagaatat cttcaatggc tattttgaag atctcaacga ggctggaaaa
     1801 gattcaaccg ctatagataa aatcaacgct cactattttg acaaaaaagc agaagattat
     1861 ttcttcaata agtttctgtt gtcttttgat ccctcaaccc agcaatggag ttacgctggc
     1921 gaatctccct ggtacggaac ggctggtgcg gcggttgtga ataaaggtga taaaacctgg
     1981 cttattaatg gcgaagccaa acccggattg cgaacggatg ccgtatttga acttgatttc
     2041 accggtgata atttaaaatg gaataggctt gctcccgtct catcaccaga tggcgtcgct
     2101 ggcggttttg cggggataag caatgattct cttatatttg ccggaggggc cggattcaaa
     2161 ggttcacgag aaaattacca gaacggtaag aactatgcgc atgaaggcct gaaaaaatca
     2221 tatagcactg atattcatct ttggcataac gggaaatggg ataaatcggg tgaattatcg
     2281 caaggtcggg cctacggagt atcattgccc tggaataata gtctattgat tattggcggt
     2341 gaatctgcag gcggcaaagc ggtgacggat tcagttttga tctctgtgaa ggataataaa
     2401 gtcacagtac aaaactaacg cttcagggcc ccggtaaagg gccctgctat caatttgtca
     2461 tttcaattac gcgaaaatta tatgaacgca ataatatcgc ccaattatta ctatgttctt
     2521 accgttgctg gtcagtctaa tgccatggcg tatggcgaag gactgccatt accggacagg
     2581 gaagatgcgc ctcatcccag aatcaaacaa ttagcgagat ttacgcatac gcatcccgga
     2641 ggcccgccat gtcactttaa cgacattatt ccactgactc actgcccaca cgatgttcag
     2701 gatatgcagg gttatcacca tcctctggca acgaatcatc aaacacagta cggcaccgtt
     2761 ggccaggcac tgcatattgc acggaaatta ctgcccttca ttcctgataa tgcagggatt
     2821 ctcatcgtcc cgtgttgccg tggcggatcg gcttttaccg cgggcagcga ggggacatat
     2881 tcagaacggc acggagccag ccatgatgct tgtcgttggg gaacggatac cccgctctac
     2941 caggatttag tcagcagaac gcgagccgca ctggcaaaaa atccgcataa caaattcctc
     3001 ggcgtatgct ggatgcaagg cgaatttgac ttaatgacca gtgactacgc gtcacaccct
     3061 caacacttta atcatatggt tgaagccttt cgtagggatc taaaacaatt ccattctcag
     3121 cttaataata ttactgccgc gccgtggttt tgcggcgata ccacctggta ctggaaagaa
     3181 aatttccctc atgcgtatga agctatttat ggcaattatc aaaataatgt tttagccaat
     3241 attattttcg tcgacttcca gcaacaaggt gaaagaggac tgacgaacgc gcctgatgaa
     3301 gatccggacg atttaagcac gggatatttc ggttcagcgt accggtcagc ggagaactgg
     3361 acgacgtcac tgcgaagcag tcatttcagc gcggcagccc gtcgggggat tatttctgac
     3421 agatttgtag aagcaatttt gcagttttgg cgcgaaaggt gagcggggag tttattcatg
     3481 ggggatgtcc ttgtccattc ccagagcaga caacaaaaaa caaatgagat caaggtaata
     3541 tctcttcact tgcgggctcg aacagcaggc aattgccaat ataataatct ggcacaaggg
     3601 tgaaaaacgc gcaccgcata aaccgttgtt attgcttaca gattagccgg atgccttaat
     3661 agacatccgc gccttttcgg ttatggctcg gaaatctacg aacatctaca cagtttactg
     3721 gaacgttttg ggccacagcg ttcgcagcac cgtcctgata tgccgttctg gcgattataa
     3781 gtcgacggat tctggcaaat agacgatgat gatatgctta atgatgttca aagaaattag
     3841 gccattatta tattattgct tgcattttct ttcattccta aaagcacccg ccattaatcc
     3901 caggcgcatt atgcaaagga aaatgattag gtaaacaata agatttataa tcaggaaagg
     3961 cgactcgcaa taaaacggaa agtcgcctta acattggtaa aatatgccct ttactactcc
     4021 tgtatcatga acggctcatc acatttaaag ctgacgttga tccagactac catatattgc
     4081 ctttatttca ttttttacgc cttcgccacg gtacaccaaa gacgtatcgt atcgttgata
     4141 cttatcttcc cgtgcagcac tgaaccagtt aaaagatccg acacacagca gttcttcatc
     4201 ctcaatcaca attttgctgt ggacacgatt aaccaatttc gtagcgatac ccatcttatt
     4261 gagcttttca acagcatcat tcagcagatg ttgtttctcc tgacgcttat catcatcgac
     4321 atgcgctata ttgcagtttt tatccgtcac cacggtaata tcaatgcccc gggaacgggc
     4381 caaagccatt gatgccagaa atcccgtttg ctccactttt tgccaagata accaagggga
     4441 aataatcgtt attttctttt gagctccggc aagagtcttg ttcaaaaatc catcatgctg
     4501 ctccacacca tgcagcgttg aaatttgtgt atgtgcggaa attaaatcct gtcgtttctg
     4561 aaactcaaat tgcaacgcat tattatctga agaaaagaga tattttgcca ataaccctcg
     4621 cggcgaaaat gcgggctgca tctcgataag gtccatatcg ccaaatacca gaaaactatc
     4681 tttagcgcgt gagacagcaa cattgaggat actgctgttg ctatcaagaa acctgccatc
     4741 ttcatgtttt gagtagacag gagaaaagag aacaatcgcc ctttccgccc cctgcaagga
     4801 gtgcacagtc cccactgtca gtgaaccctg ctcgtctttg ccattaattt ccagcttacg
     4861 caatgacgtt ttgatagcat taacctgcgc cgaaaatggc gtcacaacac caacaacttt
     4921 gtacagtggt tccccgtaat ggcgctctat atcatcctta tgtgccacca gccatgctgc
     4981 tattgtttca gcttcaagag ggttataacg gcttcctcca tttggcttca tgcctctacc
     5041 atcaatatgt aaatatccca ttgcggggaa aatcgtccct ttttccatcc ctcttttagg
     5101 ctgcaactta ccgtgatagc aaagtgagtt acagtagccg atgatgttat tgaaacagcg
     5161 acgatgctca tacagataca ttccgcgctc gaacttggga tcatactggt agtgagagtt
     5221 gaactgggct acctgcatta cgctgccaga tgctgcactt tttccagacc catttattat
     5281 cgaatacggt gaccgcctga gcggccacct ttaatcgtgg gcagttacac agaattattt
     5341 acagggcctt gctgggagtt cttacacttg ctcgcgatat tcaattggcc attgtcaaca
     5401 agatgacgca ggttttgatt ggtgatatct atttacgtca gcaatgcgat gtgttttggc
     5461 tcggctatac catcagtccc gcttatactc gccagggata tgcaattgaa gcaattaccg
     5521 ccacgattga ctggataaaa gagaacggtt tttcactcat caaagccggt gtgaatccgg
     5581 aaaataccct ttcaaaaaaa ttacttatca ggattggctt caatttttcg agcatcgaag
     5641 atgggtgagc atatttatgt tctggattaa acaaaaggag aataatctcc cgaagggaaa
     5701 agccgatgag gccatttcag gcgtacttca acatgcattc gtcagtgtca tctgcctttt
     5761 ccagtaaatg ggttggcatt caatttccaa agtacatcac actttttcta ctgaaacata
     5821 tccctcctat aactacgtgt taatattcgc tccgtaaata cctttcaact caacccgagg
     5881 ctttgatgct ggagaatgta atcatccgat aatcagttcc ccgacctttt caggccggac
     5941 tgattatcaa tgcgccgaaa tcgaatgcgg acaccgcggt gtgtttgcac gttttgcaca
     6001 tgatgattaa acaggttctt cagtatgaat ttatcccgtc aggaacaacg tacgttacac
     6061 gttctcgcta aaggtggacg tattgcgcac gtccgcgatt cttcaggccg cgtcacttcc
     6121 gttgaatgct acagccgcga agggctgttg ctgaccgact gcacgctcgc cgtcttcaaa
     6181 aaactcaaaa ccaaaaaact tatcaagtcc gtcaatggtc agccctatcg aatcaacact
     6241 accgggctga ataacgttcg cgctcagctc gataatcgct aaggagagtt tcgatgacag
     6301 cacaccactt cacttttcaa atcacagatg aaagtgatgc cagtgatatc cgggaagtcg
     6361 aaacccgcgc atttggcttc agcaaagaag ccgatttaac ggcctcttta cttgaggatg
     6421 aaagcgcgcg ccctgcgtta tcgctgctgg cccgacatga aggcaaagcc gtcgggcata
     6481 ttttatttac ccgggcaacc ttcaaagggg aaatggattc accgctgatg catatcctcg
     6541 ctcccctggc agtcataccg gaataccagg ggatgggcgt gggaggacgg ttgatacgca
     6601 ctggcatcga gcacctgagg ttgatgggct gccagacggt ttttgttctc ggccacgcca
     6661 cctattaccc ccgacatggg ttcgaaccct gtgccggaga caaaggctat ccggcacctt
     6721 atcccatccc ggaggagcac aaagcctgct ggatgatgca agcactcacc gctcagccca
     6781 tgaacgtgac cggccacatc cagtgcgcgc aggccctgat gaaaccggag cactggcgtg
     6841 aataacaatc ttgttgtgcc ctttttaatg cttaacccaa taacaggaat taactaatgg
     6901 atattccacg tatttttacc atcagtgaaa gcgaacaccg catccacaac ccgttcaccg
     6961 aagagaagta cgccacgctg ggtcgcgtgc tgcgcatgaa accagagacc cgaattctgg
     7021 acctcggcag cggctcgggc gagatgctct gcacctgggc ccgggatcat ggcattacgg
     7081 ggactggaat cgacatgagt tcgctcttca ccgcgcaggc cagacgccgc gcggaagaac
     7141 tcggcgtcag cgaacgcgta cattttattc ataatgatgc ggcgggttac gtcgccaatg
     7201 aaaaatgtga cgtagcagcc tgcgttggcg cgacctggat tgccggaggc tttgccggga
     7261 cagtcgaact gctggcgcag agccttaaac cgggcgggat catgctcatc ggtgaacctt
     7321 actggcgtca gcttccggca acggacgaga tagcccaggc ctgtggcgtc agctcgacga
     7381 ccgattttct gacgctacca gggcttgtca gcgcgtttga cgacctcggc tacgacgtgg
     7441 tggaaatggt actggcggac caggaaggct gggaccgata tgaggccgcg aaatggctga
     7501 ccatgcgccg ctggctggag gccaatcctg acgatgactt cgccgccgaa gtcagggccg
     7561 agctaaacat ctcgccgaaa cgccacgtaa cgtacgcgcg ggaatacttt ggctggggcg
     7621 tgttcgcact catcgctagg taacaacagg ttcccggtat ttctgactgg agataccggg
     7681 ggcttagcct ttgctttaat ctgatgcatc acctgcacaa tacatattca gtatgtttat
     7741 taatcaagat gtcaccataa ggagcatcat atgtcacaac atgaacagtt ctgtcaggct
     7801 tgcggaatgc cgatgtcggc accagatgca cacagtgcca gtgatcaata ttgtgcgtac
     7861 tgcagcgaca gcaacggcaa tctcaaaccc tgggaagaag cggtatcagg tttagccagc
     7921 ttccttgatt cctggcaaaa agtcggcccg gaggaagcac ataagcgtgc aaaacgttat
     7981 ctgacggcaa tgccagcctg ggctcataaa gcggagagtg atttgagctg attatctata
     8041 ctccctctga atctattcag gagatccgat gttttcttac attatgctgg gaaccaacga
     8101 cctgccacgc gccattacat tctaagatcc gctgatggag atgctggggt atccacgtgc
     8161 aggacgtaat gaagagggag cgtcctgcaa caaagtggtg cgataacagt taccgcgttt
     8221 tattcattct cattatttca accataatca ctggtctctc tagcccgtaa ctttcacaaa
     8281 cgttgagcgc ttttattcca ctcggctcac ataatttttt atttgttcag ctttgcgcgt
     8341 tttcacgtga acgttctcac aattattcga ccagtctgcg cctataaaac gctcaacgag
     8401 tgattgtttt acggtctacg gagatagcta tgtcattttc tgtgcaggaa accctgttct
     8461 cgcttttgca gcacaatgcg atttcaggac acgaaaacgc tgtcgctgac gtcatgctgt
     8521 gcgaattcag gcgtcaggca aaagaggtct ggcgagacag gcttgggaat gtcgtcgcgc
     8581 gctacggtag tgataaaccc gatgcgctgc gactgatgat ttttgcgcat atggatgaag
     8641 tcggttttat ggtgcgcaaa atagagcctt ctggattttt acgctttgaa cgcgtaggcg
     8701 gtcctgcgca ggtcactatg gctggatcca tcgtcaccct caccggggac aaagggccag
     8761 tcatggggtg tatcggcatt aagtcctacc actttgccaa aggcgacgag cgcacgcagt
     8821 caccttctgt cgacaaactg tggattgata ttggtgccaa agacaaagac gacgctatac
     8881 gaatgggcat tcaggtcggt acgcctgtca ctctgtataa cccgccgcaa ctcctggcaa
     8941 acgatctggt gtgcagtaaa gcactagacg atcgtctggg ctgtactgcc ctgctcggtg
     9001 tagcggatgc tatcagtact acggagcttg atatcgccgt ttatctggtg gcttcggtac
     9061 aggaagaatt taatatccgc ggcattgttc ccgtattacg ccgtgtaaaa cctgacctgg
     9121 cgattggtat tgatatcact ccatcgtgtg acacccctga tttacacgat tattccgagg
     9181 tcaggattaa tcagggcgtt gggatcacct gcctgaacta ccatggtcgg ggaacgctgg
     9241 ccggattaat cacgcctcct cgcctgatac ggatgttgga acagacggct cttgaacaca
     9301 acattccggt gcagcgagaa gtggctcccg gcgtgataac agaaaccggt tatatccagg
     9361 ttgagcagga tggtattccc tgcgccagtc tctctattcc ttgtcgctat acccattctc
     9421 cggcggaggt tgccagcctg cgtgatttga ctgattgcat ccgcctattg accgctctgg
     9481 caggtatgtc agcagcacat ttccccgttg agcctgattc aggcactaca caagaggcac
     9541 atccattatg aaaaagatcc ttgtggcatg cggtaccggc atgtcgactt caaccatgat
     9601 tgcacacaag ctgcaagagt tcctgactga acagggcatt tcagccacta ccgcccaatg
     9661 ctgtctgaat gagatccctc ttaactgtaa cggtatggac cttattgtaa cctccatgcg
     9721 aaccaacagt gattacggca tccctacgct taatggcgcc gccctgctca cagggatcaa
     9781 cgacgacgcg ttaaaacaac aaatcaaggc tctgttaact caataaaagg aggcattatg
     9841 tttgattaca tcctgtctct cggcggtacc gttttcgtcc ctatcatcat gatcgtgatt
     9901 ggccttatct tccgcatccc ctggctgcag gcgattaagg caggggtaac ggttgggatt
     9961 ggttttgtcg gtatgggact ggtgatcgtc atggcgatcg acagcctcag tccccctatc
    10021 aaagtgatga ttgagcgttt cggcctggcc ctgcatgtct ttgacgttgg cgcaggccct
    10081 gcctccggcg ttggttatgc gacagccatt ggcgccatga ttatcccagt tatttttctt
    10141 ctcaatgtcg ccatgctggt cacccgtctg accaaaacga tgaacgtcga tatttacaat
    10201 tactggcact acgccattac gggtacggtg gtccagctta tgaccggtag cctgatttat
    10261 ggtgtgctgg gggcaatctg ccatgcggcg ctatcgttaa aaatggccga ctggacggca
    10321 aaacgggtac agaacatcgt cgggctggaa ggtatttcga taccgcaagg ctacggttcc
    10381 agttcagtac cgcttttcgt tctacttgat gctatctatg aaaaaatccc tttcatgaag
    10441 ggacgcaata tcgatgctca ggagatccag aaacgctacg gcatggtcgg cgatccggtg
    10501 attatcggcg tagtgctcgg tctgattttt ggcctggcgg ctggtgaagg ctttaaaggt
    10561 tgcgccagtc tgatgattac cgttgcggca atcatggtgc tgttcccgcg catgatccgc
    10621 ctgattgttg agggcctgat gcccatctcc gacggtgcaa gaaagttctt ccagaaatat
    10681 ttcaaaggac gtgaagtgta tatcggtctg gatactgctg tgacgctggg gcatccaacc
    10741 accattgctg tcggtctgct actgataccc attatgttaa ttctggccag cattttaccg
    10801 ggcaacaaag tgttacccct cgcagacctg ccggtagcac cgttctttat ctgtatggct
    10861 acggttatcc accgcggaga cctggtcagg acgttgataa gcggggtcat cgtgatgatt
    10921 accgtcctgc tgatcgccac ccagttcgcg ccttacttca ctgaaatggc gctcaaaggc
    10981 ggtttcagtt ttgccggtga aagtgcgcaa atctcagcgt tgtccgtggg caatatgttc
    11041 ggttggtcga tttctgaatt gatgtcgctt gggattattg gcgttgtcgt ggcggtcggt
    11101 attgtcgcca gcgtcgtgct gttcttacgt aaacgtgaat tatcggaata aggagtactt
    11161 tcaatgagtt ggctgaaaga ggttattggg acggaaaaag cggtcatcgc catgtgccat
    11221 ctacgtgcat tgcccggcga cccgagtttt gatgcgcagt tggggatgaa ctgggttatc
    11281 gacaaagcct gggacgatct gatggcgctc caaaatggtg gggtggatgc agtcatgttc
    11341 tccaacgagt ttagtcttcc ctatctcacg aaggtgcgtc cggaaaccac tgcggcaatg
    11401 gcacgaatca tcgggcaatt aatgagcgat atccgcatcc cgtttggcgt gaatgttctg
    11461 tgggatccgg tcgcctcatt cgacctggcg atggctaccg gcgctaagtt tatccgcgag
    11521 atatttaccg gtgcctatgc cagcgacttt ggcgtctggg acactaacgt cggtgagacc
    11581 atccgtcatc aacaccggat tggtgcaggc gaagtgaaaa ccttgttcaa tatcgtccca
    11641 gaggccgccg tgtatctggg caatcgcgat atctgttcta ttgctaaatc gacagtattt
    11701 aacaaccatc ctgatgcgct ctgtgtttct ggcctgaccg ccgggacgcg tacagacagc
    11761 gcgctgttaa aacgggtcaa agaaacggtg cctgacaccg tcgtgttggc caacacgggc
    11821 gtctgcctgg aaaacgtgga ggaacaactc agtatcgccg atggctgtgt gaccgcaacc
    11881 acctttaaaa aggacggcgt ttttgccaat ttcgttgacc aggcgcgagt cagtcagttt
    11941 atggagaaag tgcatcatat acgccgataa gatagggata agcagagcgc ttatccccgg
    12001 caaagagcaa taacccttct gcgatccctg ccgccttcgt caaaagtatc gacggggatc
    12061 gctaccagat taacccgaat cggcatggag tcaacgacgg atgattaacg atattaaatg
    12121 ggtacaggca caacgtgaag ccaccgactg gcgtcaggcc gtggaaatcg ccacccgccc
    12181 gctggtagcc tatggtgccg cgcagccatg ctacgttaat gggatcatcg aaaataccct
    12241 taactggggg ccttattatc tgatagcccc aggaatcgcc ttgcctcacg cccgaccaga
    12301 gcaaggcgca aactataatc aggtcagtat caccacgcta cgcaccccgg tcgcctttgg
    12361 taacgaggag tgcgaccccg tctggctgct tctctgcgtc agcgccacag atgccaacgc
    12421 acatattttg accattcagc gcatcagcca gtttattgat tcgccacaac gcttagcggc
    12481 agtgggaaat gccagcacag acgatgcact gtttgcgctg gtatcaggtt aacggaggcg
    12541 cttatgatcc tgcacccttc tctcgccagc gcaaatcctc tgcactatgg tcgtgagctg
    12601 acggcattgg acaatctgga ttttgggagc ctgcatctgg atattgagga cagcagcttc
    12661 attaacaaca ttacgtttgg gatgaaaacg gtgcaggccg tcgccagaca gacgcctcat
    12721 cccttgtcct ttcatttcat ggttgcccgg ccacagcgct ggtttaacgc gctggctgaa
    12781 atcagacccg cgtggatctt cgttcatgca gaaacgctgg actatccttc ggaaacgtta
    12841 actgagatcc gccataccgg cgcacgagcc ggactggtat ttaatccggc aaccccgatc
    12901 gacgcctggc gatatctggc gtctgagctg gacggagtga tggtgatgac cagtgagccc
    12961 gatgggcagg gacagcggtt tattccctcc atgtgcgaga aaatccaaaa agtacgcacg
    13021 gcttttcctc agaccgagtg ctgggccgac ggtggaatta cgctggcagc tgcacagcaa
    13081 ctggcagcag ccggggcgca acatatggtg attgggcgcg ccctgttctc ttcatctgac
    13141 tatcgcgcga ccttagctca attcgccacc ctgtaagagg agattgtttc tgatgagcca
    13201 acagagacct gaccgtatca aacagatgct gcactacctg tggcaacatc gtcacctctc
    13261 cacacagcag gccatggagc tttttggcta tgcggaagcg actgtccgtc gtgatttcca
    13321 gtatattgcc aaccagtatc caggcatgat ccgcggtcac ggttgcctgg acttcgacga
    13381 cagtacagac gacaaagagt acgtcttcga cgtgaaacgt acattgcaat ctgtggcgaa
    13441 aagagaaata gctgcccttg cccgaacaat gatcaaagat ggcgactgct tttttctcga
    13501 ctccggctca acctgcctcg aactggcgaa atgcctggcc gatgcgcggg taaaggtcat
    13561 ctgcaacgac attaaaatcg ccaatgaact gggctgtttt ccccatgtgg aaagttacat
    13621 tatcggagga ctgattcgcc caggttattt ttcggtagga gagagtctgg cgctggagat
    13681 gatcaatgcc ttttccgtag aacgtgcgtt tatctcctgc gatgcgctgt cgctggagac
    13741 ggggatcacc aatgccacca tgtttgaggt cggggtgaaa acacggatta ttcaacgctc
    13801 gcgtgaagtt attctcatgg ccgatcactc aaaatttgat gccgttgagc cgcatgctgt
    13861 agcaacacta tcatgtatta aaacgatcat cagtgacagc gggttacctg agactattgc
    13921 acagcgttat cagcgagccg gatgtcagtt gtttttacct cattcaataa agtgataagt
    13981 aagttcgttc gagagggatt tcaagcaaaa ataatcaatg gcacccaata gaaaatattg
    14041 gcgatgcgct cgaacgaata aagaagccct atgcgcaatc cacacgctac gatgttgcaa
    14101 caacacgcca tctacttttt attctcattc actaaatgtg gttgttctgg attcattatt
    14161 caaagtgtgt acaagatcac atttaatcac ttcattacag ttcagcatgc tgaacaaagc
    14221 atattttcca ctatgtaatg ccgataccat ttattccatg agcaagaagg agccattatg
    14281 gttcgcaaag ggtgtaattc attagtccgt gctgaaaaaa tattaaccca cattgcatgg
    14341 gttggtatgg caagttatat ggagttatta aataaattcc agtaccccaa aagcagcctg
    14401 cttaatttat tgaatgtaat ggtggagtgt ggtttcttaa ttaaaaacaa aaacggctac
    14461 tattcactgg gaataaaaaa ctacgaattg ggttgtcagg cgttacaccg tcaaaatata
    14521 tttgaggtga ctaagcggcc aatgcaggag ttgtcgctga aaagtggact ggtttgtcat
    14581 cttggggcga tggagagcat ttcggctatc tatctcgaca agatcgaaag tccggactct
    14641 gtaccgacga gcaaaagctg gattggcaaa aaacttgagt tgcatattac cgcgttgggt
    14701 aaggcattat tagcctggaa gacacgagaa gaactggatt attttttaga agcactcacg
    14761 ttaactccac atacgcgcaa tacatttacc gataaaaaat tgtttctgga agaattacaa
    14821 aaaacacgcc ttcggggatg ggccatagac aacgaagaat caacctatgg ggcggtatgt
    14881 ttaagtatgc cggtattcaa tatgtataac agagttaact atgcaatctc actttctggc
    14941 gatccggtag tttattcagg aaataagata gacagctatc tggaattgct ccggaaatgc
    15001 gctgagcaaa tatcatatgg gctgggatac agaaacgaaa atgagcattt acgaaaagga
    15061 aactgaggta atgaaaaaat tcagcggcat tattccaccg gtatccagca cgtttcatcg
    15121 tgacggaacc cttgataaaa aggcaatgcg cgaagttgcc gacttcctga ttaataaagg
    15181 ggtcgacggg ctgttttatc tgggtaccgg tggtgaattt agccaaatga atacagccca
    15241 gcgcatggcg ctcgccgaag aagctgtaac cattgtcgac gggcgagtgc cggtattgat
    15301 tggcgtcggt tccccttcca ctgacgaagc ggtcaaactg gcgcagcatg cgcaagccta
    15361 cggcgctgat ggtatcgtcg ccatcaaccc ctactactgg aaagtcgcac cacgaaatct
    15421 tgacgactat taccagcaga tcgcccgtag cgtcacccta ccggtgatcc tgtacaactt
    15481 tccggatctg acgggtcagg acttaacccc ggaaaccgtg acgcgtctgg ctctgcaaaa
    15541 cgagaatatc gttggcatca aagacaccat cgacagcgtt ggtcacttgc gtacgatgat
    15601 caacacagtt aagtcggtac gcccgtcgtt ttcggtattc tgcggttacg atgatcattt
    15661 gctgaatacg atgctgctgg gcggcgacgg tgcgataacc gccagcgcta actttgctcc
    15721 ggaactctcc gtcggcatct accgcgcctg gcgtgaaggc gatctggcga ccgctgcgac
    15781 gctgaataaa aaactactac aactgcccgc tatttacgcc ctcgaaacac cgtttgtctc
    15841 actgatcaaa tacagcatgc agtgtgtcgg gctgcctgta gagacatatt gcttaccacc
    15901 gattcttgaa gcatcagaag aagcaaaaga taaagtccac gtgctgctta ccgcgcaggg
    15961 cattttacca gtctgaggag aaactcatgt ctgttcgcaa tatttttgct gacgagagcc
    16021 acgatattta caccgtcaga acgcacgccg atggcccgga cggcgaactc ccattaaccg
    16081 cagagatgct tatcaaccgc ccgagcgggg atctgttcgg tatgaccatg aatgccggaa
    16141 tgggttggtc tccggacgag ctggatcggg acggtatttt actgctcagt acactcggtg
    16201 gcttacgcgg cgcagacggt aaacccgtgg cgctggcgct gcaccagggg cattacgaac
    16261 tggacatcca gataaaagcg gcggccgagg ttattaaagc caaccatgcc ctgccctatg
    16321 ccgtgtacgt ctccgatcct tgtgacgggc gtactcaggg tacaacgggg atgtttgatt
    16381 cgctaccata ccgaaatgac gcatcgatgg taatgcgccg ccttattcgc tctctgcccg
    16441 acgcgaaagc agttattggt gtggcgagtt gcgataaggg gcttccggcc accatgatgg
    16501 cactcgccgc gcagcacaac atcgcaaccg tgctggtccc cggcggcgcg acgctgcccg
    16561 caaaggatgg agaagacaac ggcaaggtgc aaaccattgg cgcacgcttc gccaatggcg
    16621 aattatctct acaggacgca cgccgtgcgg gctgtaaagc ctgtgcctct tccggcggcg
    16681 gctgtcaatt tttgggcact gccgggacat ctcaggtggt ggccgaagga ttggggctgg
    16741 caatcccaca ttcagccctt gccccttccg gtgagcctgt gtggcgggag atcgccagag
    16801 cttccgcgcg agctgcgctg aacctgagtc aaaaaggcat caccacccgg gaaattctca
    16861 ccgataaagc gatagagaat gcgatgacgg tccatgccgc gttcggtggt tcaacaaacc
    16921 tgctgttaca catcccggca attgctcacc aggcaggttg ccatatcccg accgttgatg
    16981 actggatccg catcaacaag cgcgtgcccc gactggtgag cgtactgcct aatggcccgg
    17041 tttatcatcc aacggtcaat gcctttatgg caggtggtgt gccggaagtc atgttgcatc
    17101 tgcgcagcct cggattgttg catgaagacg ttatgacggt taccggcagc acgctgaaag
    17161 aaaacctcga ctggtgggag cactccgaac ggcgtcagcg gttcaagcaa ctcctgctcg
    17221 atcaggaaca aatcaacgct gacgaagtga tcatgtctcc gcagcaagca aaagcgcgcg
    17281 gattaacctc aactatcacc ttcccggtgg gtaatattgc gccagaaggt tcggtgatca
    17341 aatccaccgc cattgacccc tcgatgattg atgagcaagg tatctattac cataaaggtg
    17401 tggcgaaggt ttatctgtcc gagaaaagtg cgatttacga tatcaaacat gacaagatca
    17461 aggcgggcga tattctggtc attattggcg ttggaccttc aggtacaggg atggaagaaa
    17521 cctaccaggt taccagtgcc ctgaagcatc tgtcatacgg taagcatgtt tcgttaatca
    17581 ccgatgcacg tttctcgggc gtttctactg gcgcgtgcat cggccatgtg gggccagaag
    17641 cgctggccgg aggccccatc ggtaaattac gcaccgggga tgtaattgaa attaaaattg
    17701 attgtcgcga gcttcacggc gaagtcaatt tcctcggaac ccgtagcgat gaacaattac
    17761 cttcacagga ggaggcaact gcaatattaa atgccagacc cagccatcag gatttacttc
    17821 ccgatcctga attgccagat gatacccagc tatgggcaat gcttcaggcc gtgagtggcg
    17881 ggacatggac cggttgtatt tatgatgtaa acaaaattgg cgcggctttg cgcgatttta
    17941 tgaataaaaa ctgaaagcat aaataaaaac atccagacac ctgaattatc cgactctgca
    18001 tcattcgtta tttgctcagt cggataatga tgggtcgcta ccctgttatg agaggacgtt
    18061 atgccactaa ttatcgttgt ggcagggatt gctttactcc tgcttttaac cataaaaatt
    18121 aagcttaata cgtttgtttc gttaattatt gtctcgattg ctgtcgccat cgccagtggt
    18181 atggatttga gtaaagtcgt cacctcagtc gaatccgggc ttggcggtac gctgggccat
    18241 attggtttga tatttggctt cggtgttatg ctcggtcgct tgctggccga tgcgggtggt
    18301 gcgcagcgaa tagcgctgac catgctgaat tatttcggga aaaataaact tgactgggca
    18361 gtggtctgtt cggcgtttat tgtcggtatc gcactttttt tcgaagtcgg tttaattctt
    18421 ctggtaccta ttttattcgc tattgcccgt gaagcaaaaa tatcaccgat gtttatgtgt
    18481 gtgccgatgc tttctggttt gctggtcgca cacggttttt tgccgccgca ccccggcccg
    18541 actgttatcg ccagggaata tggcgctgat gtaggattgg tactgatata cggtatcatt
    18601 gtcggcattc caacctttat tctttgcggc ccggtattga ataaattctg ccagcgcatt
    18661 attccggacg cctttaaaaa agaggggaat atagcctctc tcggcgcgac ccgccgattc
    18721 agcgaaagcg aaatgccagg ctttgggatc agttttctca cggcaatgct gccggtgatc
    18781 ctgatggcgg ttgtcaccat catccagatg actcatgcca aaagtgccgc ggattctggc
    18841 ttattttaca acgtgatact gttcttaggt aattcgacga tcgccatgct gatttcactg
    18901 ctgttcgcga tctataccat gggcctgggg cgcgggaaaa caatccctga cctgatggat
    18961 tcttgcggaa aagctatcgc gggtattgcc ggtctgctgc tgattatcgg tggtggtggt
    19021 gcattcaagc aagttctcat cgactctggc gttggtcagt atatttccac cctggtttcg
    19081 ggtatggata ttaacccgat cttgatggcc tggggcgtgg ccgcattcct gcgtatttgt
    19141 ctgggttcag ccaccgtcgc ggcgatctct accgccggtc tggtcatccc attgttggca
    19201 gtacatccca ataccaacct ggccttgatt acgctggcta ccggtgccgg atcctgtatt
    19261 tgttctcacg ttaacgatgc cagtttctgg atgattaaag acttttttgg cctgaccacc
    19321 aaagaaacgc tgttatcctg gacgttgatg tccacactct tatccatcag tgggctgatt
    19381 tttattctgc tcgccagctt agttttataa tcgggttctt gccagtgagc caacctgttg
    19441 ttcactgtcc cccataattt agtgagtgac ggcaaccgtc tgcacggtga cgaatcgctg
    19501 gcgatcaaaa aggggcgata ttgaaccgtc gattatgctt gatgggtgta ctctcagtaa
    19561 tactgtaaag ccggagcatg tctccgactt tacagtatgg gggaacagca ggcgatcgct
    19621 caaatggtat gctggtttat ttcatgtaaa agaataaaat atctgtataa aatcatgcca
    19681 ctggcaatct gcatcaactc tccgggtaaa cagggttaag atgagcattt ccccggttta
    19741 atacaggtat acaaaagtgg atagagatca aacaaacagc agcctgttca atgatgatcc
    19801 cgtacttcat gcaacatggc tgtactatca ggaaggcaaa agccagactg aagttgcagc
    19861 tatcatgggg gtgtcccgcg tcacggttgt caaatacctg caaacagccc gggaaaatgg
    19921 actggttcat atcaacctgg atgtgaatgt ctttggctct atcgacgctg ctttgcaaat
    19981 tcgcgataaa ttcaatctcc agagagtgat catcgtgccg gatggcgaac atgccggaaa
    20041 acgtgatgat acaaagctga tgcggactcg cctttcacgt gccggtggca tgtatctgaa
    20101 tcaggtgatt gagaatggtg atgtgctggg ggttgcctgg ggaagaacaa tccatcagat
    20161 gagcaaaacc atgacgccga agtcatgtaa aaatgtcacc gttatacaga tgctcggttc
    20221 catgccatct cagccagacc tgacgatcat tgaatcctca tcgcaaatcg cctacaagct
    20281 ttcaggccgt gtcgcctcgc tgcacgtgcc cgccgtggta tcaagcgcca gactggccat
    20341 ggagttacag gcagagccta ttattcgatc gaattttgac gttctgactc gctgtacgaa
    20401 agcctttttt gtcgtgggta acgcgcttga tgaaaatccc ctgattcggg tgggcgtgct
    20461 gaataagaag gaaatgcaga cgtatcggga tttaggcgca gtaggtgtca tttgtggtcg
    20521 cttctatgac aaggaaggga tgcccgtcgt ggctgatgtt gaccagcgta ttctgggaat
    20581 cagtctggct cagctaaggc agattgaacg gaagatcttc cttgctggtg gggaaagagg
    20641 ctatgacgca acgttgggtg ccctgctggg aggatatgtc acggacctga ttgttgatga
    20701 aggaacggca gagtttttgc tggcgtgtga attaccacac taaaagaatg aacaactgcc
    20761 ccatgtggat atggggcagg attttattga ttagcggcga taataagaac aatacccaca
    20821 atgtatgaaa taaacatggt cagcagcagt ttattggttc cggctggcgc actggcaaat
    20881 tctctccaga tgaagactcc ccagatcacg gcaatcattg tggccccctg tcccagaccg
    20941 taggaaatgg cataccccgc ctgaccagac gcaatcagac tgaatgccag accgacacac
    21001 caaatcatac cgcccagcca gccgcaaaca tgatcccgta agctcccgga aaaatacatt
    21061 ttcccgttga ccggttctcc tgaaataggt tttttcatga ccagcgtgtt aaggacaaag
    21121 ttcgacaaga acagccccac ggcaaacaga acaagtgctg agtaaggcgt catcagaccg
    21181 ctggcaggct ggctgaaatt gtcagacatg gagtccgcca agaagcggaa aaaccatccc
    21241 atgatgatac ccgccagaat ggcagtaatg agacctttat tacggcgaga tttatccgcc
    21301 tcctgcgtga cacgaccata ggctatcgcg gtaaaaataa tggcgatcac aacgcaggcg
    21361 acaccgagga acagaatgag cggatcgccc tgcggattgc cgatataggt ggtgatcaca
    21421 cccagagcca gtgccagccc cacacccaca ggaaaagcta ccgccatacc ggcaagatta
    21481 atagaagcga ccagaagaat attggaaata ttgaagataa tccctgccag tattgccgac
    21541 atcagactac tgctgctcgc ctgctgaata tcaggtataa aactgcgacc ggcttcgccc
    21601 atagaaccca gcgtgaaggc aaataacaaa gaacacagca ataatccaat tgaataatcc
    21661 caatagaata gagggaactc ccatttttta ttgctgacaa gtttagttgt attcgcccat
    21721 gaaccccagc aaatcatggt aataaaacac attattatgg cgacagcata cgattccacg
    21781 ataaacataa ataactcctt gtggtagtta taatcaatcg ttgtggacag agggaatagc
    21841 agccattctg cgaatggctg tcatatgtta ttaattaaaa taaagctgta attacgcttt
    21901 caaaccatac gttttgaatt tttcaaggac gatggtcatt tcggcttcag acagcacggg
    21961 aacatcgtga tgtaatccgc cacatttgat gtataaatca gccagcgtct cggtttcacc
    22021 cgccagccac aacgtctttt ccagcgtgac gtccatggcc agcataccgt ggtgctgcat
    22081 cagcaaggac ttactttctc tgattccttt agatacaccg tcggccagtt caggactgcc
    22141 aaaggtataa tagggaatac agggaatatg atccgtcccc gataccgcca ccatataatg
    22201 aatggccgga attgaatgat tatgtattgc caccgccgtg gaattcaccg catgcgtatg
    22261 tatgacagca ttcaattctg gtctggcttt ataacacgcc agatgaaata accattcact
    22321 tgatggtatt ttacccgctt caggtattcc cttatcgtct acaaagacaa tcatgtccgg
    22381 cgtcatcttt gaataagcga tcccactcgg cgtaatcaac atgccaccgg tatacctggc
    22441 actcacatta cctgatgttc cttgattaag acctgacgca ttcatttccc gacaagtgga
    22501 aatgattttt tctgctaact taatccgttc cattcctgat ccttaatagc aatggccgcc
    22561 gttttaatgc tgttccccct ggagtgcttt actcttcagg tcagcaaaca tatccgccag
    22621 cgctgactta ctggcagcac agactccccg ctcagtaatg aagccggtaa tgtatcgggc
    22681 aggcgtgacg tcgaaagcgt agttcccaca acgggttcct tcaggggcgg tattgaccca
    22741 gctcaattct ccctgagggt ttatcccata gacatgggac tgctcttttc cgtcacgttg
    22801 ctcaatcgga atgctttttc cgtcctcgat agtccagtca atagtgggag aaggtaacgc
    22861 gacgtagaag ggaacatggt tatcatgggc cgccagcgcc ttaagatagg taccaatttt
    22921 attacagaca tcccctctgg ccgtggttcg atcggtccca acaatgcaga gatcaacgtc
    22981 accgtgttgc atcaggtggc cacccgcgtt gtcggcgatc agggtgtgag gaataccgtg
    23041 tgagcccagt tcaaatgccg tgagtccgcc ctgattacgt ggccgcgttt catccaccca
    23101 gacgtgaaca gggattccgt tttcatgcgc tttgtagatg ggagaaagcg cggttcccca
    23161 gtctacagtc gccagccagc ctgcgttaca atgtgtcagg atattgacca cactcccggc
    23221 cggttttttc tgggctattt cgcggatgac ttctgtacca tgtaatccaa tttgttcaca
    23281 caacgcgaca tcttcctcgg caatttctgc cgccagcgcc caagccacat ccttgcgctc
    23341 tgatacacag agatccttca gtgtgtctat catcctgtcg agggcccatt tgagattaat
    23401 tgccgttggt cgggttttga taagaaggtc atagtaacgc tgcagaccca tgtcactggc
    23461 atcgtgattc attcccagcg cgatgccata ggctgcaacg acaccaataa gcggagcgcc
    23521 acgaacccac atctcctgaa tagccgtagc ggccatttcc gcagaggtaa gcgccaccac
    23581 ctcgaactta aaaggcaact tagtctgatc gatgatttct accgcttttc catccccgga
    23641 aacccagacc gtacgatagt gtttaccttt aatattcata atgacctctt acttaacctt
    23701 cgcagactgg atgacggaat ccatattttt aaactggcgg gcattgacga taagatcgcg
    23761 cgccatggtc aatgcacgtc gttcacatcc tgcgcgaagc tctgtatttt caatctgttt
    23821 cagctcggca acgccagcaa aaccaatgat ccggcgattc atttccatgc cggcattcac
    23881 cagggaatct tcaagcagcg tggcaaaaaa ctgatcctgt gcgtcctcaa gagcggccct
    23941 gttctgttga tacatttctg tcggccacgc gtcgccctgt gttttgttgt cccagagctg
    24001 gcggaactcc cgggtgaaaa cggaccaggt ttggacaatc tgctgaagca gccattcctg
    24061 atagtcagcg cgacgttgct cattcgcatc ccacccaggg cgtgagaagt acgccagcag
    24121 gaggttgcca atatagttgc cgatatcaaa cgccattggc cccatgaaac cgaactccgg
    24181 atcaatcact ttggtatccg tgtcggtcac catgattgag cctgaatgaa ggtcgccatg
    24241 taacaatgcc tgcgcttctg tcataaattt gtacttataa cgcatggcaa cctggatcat
    24301 ctctacatca gcccaggcct tatggacggc atcgtccagc tcaggagaag tccagttatt
    24361 ccgttcagcg ttgtaatagg gctctgtgaa gatcagatct tccgtaattt tgcacagctc
    24421 atgattcaac gcgaactcgg cagtaagcgc ttttttctgt tctgctgaca tgccaatgtc
    24481 agacgtattg aagagagtct gtgctaaaaa tctgccgata tcttcagcta gtttagggaa
    24541 ttttttaccg ttaatcagtt ccttacgcag aatcacgtga ggagtcagat actccatggc
    24601 aaacagcgcc atttccgggt cgtaaaaata gacctgcgga atcagtgtgt gacccgcgta
    24661 cttggcttcc tgacataaga cgttgtactc aaagcccgca cggctcagag ataaaggcca
    24721 tccttcgccc cctgcacgaa gccagggcag agcttgtttt acaatgatgg ttttatgtgt
    24781 cccctcaacg ataaacacca tgttcaggtt tccgtccccc acttctgaaa ctttccactc
    24841 ttcaggtaac cctcccggtt cgcatgaagg ggtcagtctg gacgagagat aacccggcag
    24901 cgtgtcacat gtcagcggct tgtaacctga tggaattgaa tccgtcataa cagttctcct
    24961 tgtctacaca gaatgataat caacttgtca tgtgacaact atacattatc aaatgtaaaa
    25021 ttatttgtga cacat
//
LOCUS       DAPGUL010000063        24482 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.063, whole genome shotgun sequence.
ACCESSION   DAPGUL010000063 DAPGUL010000000
VERSION     DAPGUL010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24482
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.063"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            108..1085
                     /locus_tag="RHX21_002769"
     CDS             108..1085
                     /locus_tag="RHX21_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415177.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEL1-like repeat protein"
                     /protein_id="HDV1987928.1"
                     /translation="MIFTSSCCDNLSIDEIIERAEKGDCEAQYIVGFYYNRDSAIDSP
                     DDEKAFYWLKLSAEQGHCEAQYSLGQKYTEDKSRHKDNEQAIFWLKKAALQGHTFASN
                     ALGWTLDRGEAPNYKEAVVWYQIAAESGMSYAQNNLGWMYRNGNGVAKDYALAFFWYK
                     QAALQGHSDAQNNLADLYEDGKGVAQNKTLAAFWYLKSAQQGNRHAQFQIAWDYNAGE
                     GVDQDYKQAMYWYLKAAAQESVGAYVNIGYMYKHGQGVEKDYQAAFEWFTKAAECNDA
                     TAWYNLAIMYHYGEGRPVDLRQALDLYRKVQSSGTRDVSQEIRETEDLL"
     gene            complement(1155..1637)
                     /locus_tag="RHX21_002770"
     CDS             complement(1155..1637)
                     /locus_tag="RHX21_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon-containing protein"
                     /protein_id="HDV1987929.1"
                     /translation="MNKVAQYYRELVASLSERLRNGERDIDALVEQARERVIKTGELT
                     RTEVDELTRAVRRDLEEFAMSYEESLKEESDSVFMRVIKESLWQELADITDKTQLEWR
                     EVFQDLNHHGVYHSGEVVGLGNLVCEKCHFHLPIYTPEVLTLCPKCGHDQFQRRPFEP
                     "
     gene            1872..4454
                     /gene="leuS"
                     /locus_tag="RHX21_002771"
     CDS             1872..4454
                     /gene="leuS"
                     /locus_tag="RHX21_002771"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008456064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HDV1987930.1"
                     /translation="MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYP
                     SGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTY
                     DNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCP
                     NDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKT
                     MQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNP
                     ELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGA
                     VMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDH
                     EAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQL
                     PVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPEY
                     KEGMLDSEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQ
                     GMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSK
                     NNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTA
                     KGDVAALNVDALTEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAP
                     TDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVED
                     STLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLN
                     LVVG"
     gene            4469..5050
                     /gene="lptE"
                     /locus_tag="RHX21_002772"
     CDS             4469..5050
                     /gene="lptE"
                     /locus_tag="RHX21_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly lipoprotein LptE"
                     /protein_id="HDV1987931.1"
                     /translation="MRYLATLLLSLAVLITAGCGWHLRDTTQVPSTMKVMILDSGDPN
                     GPLSRAVRNQLRLNGVELLDKETTRKDVPSLRLGKVSIAKDTASVFRNGQTAEYQMIM
                     TVNATVLIPGRDIYPISAKVFRSFFDNPQMALAKDNEQDMIVKEMYDRAAEQLIRKLP
                     SIRAADIRSDEEQTSTTTDTPATPARVSTTLGN"
     gene            5050..6081
                     /gene="holA"
                     /locus_tag="RHX21_002773"
     CDS             5050..6081
                     /gene="holA"
                     /locus_tag="RHX21_002773"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HDV1987932.1"
                     /translation="MIRLYPEQLRAQLNEGLRAAYLLLGNDPLLLQESQDAVRQVAAA
                     QGFEEHHTFSIDPNTDWNAIFSLCQAMSLFASRQTLLLLLPENGPNAAINEQLLTLTG
                     LLHDDLLLIVRGNKLSKAQENAAWFTALANRSVQVTCQTPEQAQLPRWVAARAKQLNL
                     ELDDAANQVLCYCYEGNLLALAQALERLSLLWPDGKLTLPRVEQAVNDAAHFTPFHWV
                     DALLMGKSKRALHILQQLRLEGSEPVILLRTLQRELLLLVNLKRQSAHTPLRALFDKH
                     RVWQNRRGMMGEALNRLSQPQLRQAVQLLTRTELTLKQDYGQSVWAELEGLSLLLCHK
                     PLADVFIDG"
     gene            6083..6724
                     /gene="nadD"
                     /locus_tag="RHX21_002774"
     CDS             6083..6724
                     /gene="nadD"
                     /locus_tag="RHX21_002774"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HDV1987933.1"
                     /translation="MKSLQALFGGTFDPVHYGHLKPVETLANLIGLTRVTIIPNNVPP
                     HRPQPEANSVQRKHMLELAIADKPLFTLDERELKRNAPSYTAQTLKEWRQEQGPDVPL
                     AFIIGQDSLLTFPTWYEYETILDNAHLIVCRRPGYPLEMAQPQYQQWLEDHLTHNPED
                     LHLQPAGKIYLAETPWFNISATIIRERLQNGESCEDLLPEPVLTYINQQGLYR"
     gene            6748..7359
                     /locus_tag="RHX21_002775"
     CDS             6748..7359
                     /locus_tag="RHX21_002775"
                     /EC_number="3.1.3.73"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin/alpha-ribazole phosphatase"
                     /protein_id="HDV1987934.1"
                     /translation="MRLWLIRHGETQANVDGLYSGHAPTPLTARGIEQAQNLHTLLHG
                     VSFDLVLCSELERAQHTARLVLSDRQLPVQIIPELNEMFFGDWEMRHHRDLMQEDAEN
                     YSAWCNDWQHAIPTNGEGFQAFSQRVERFIARLSEFQHYQNILVVSHQGVLSLLIARL
                     IGMPAEAMWHFRVDQGCWSTIDINQKFATLRVLNSRAIGVENA"
     gene            7619..7936
                     /gene="rsfS"
                     /locus_tag="RHX21_002776"
                     /gene_synonym="rsfA"
     CDS             7619..7936
                     /gene="rsfS"
                     /locus_tag="RHX21_002776"
                     /gene_synonym="rsfA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007373852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HDV1987935.1"
                     /translation="MQGKALQDFVIDKIDDLKGQDIIALDVQGKSSITDCMIICTGTS
                     SRHVMSIADHVVQESRAAGLLPLGVEGENRADWIVVDLGDVIVHVMQEESRRLYELEK
                     LWS"
     gene            7940..8407
                     /gene="rlmH"
                     /locus_tag="RHX21_002777"
     CDS             7940..8407
                     /gene="rlmH"
                     /locus_tag="RHX21_002777"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HDV1987936.1"
                     /translation="MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRG
                     KNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLAAELERWKLDGRDVSLLI
                     GGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE"
     gene            8438..10339
                     /gene="mrdA"
                     /locus_tag="RHX21_002778"
     CDS             8438..10339
                     /gene="mrdA"
                     /locus_tag="RHX21_002778"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-transpeptidase MrdA"
                     /protein_id="HDV1987937.1"
                     /translation="MKLQNSFRDYTAESALFVRRALVAFLGILLLTGVLIANLYNLQI
                     VRFTDYQTRSNENRIKLVPIAPSRGIIYDRNGIPLALNRTIYQIEMMPEKVDNVQQTL
                     DALRSVVDLTDDDIAAFRKERARSHRFTSIPVKTNLTEVQVARFAVNQYRFPGVEVKG
                     YKRRYYPYGSALTHVIGYVSKINDKDVERLNNDGKLANYAATHDIGKLGIERYYEDVL
                     HGQTGYEEVEVNNRGRVIRQLKEVPPQAGHDIYLTLDLKLQQYIETLLAGSRAAVVVT
                     DPRTGGVLALVSTPSYDPNLFVDGISSKDYSALLNDPNTPLVNRATQGVYPPASTVKP
                     YVAVSALSAGVITRNTTLFDPGWWQLPGSEKRYRDWKKWGHGRLNVTRSLEESADTFF
                     YQVAYDMGIDRLSEWMGKFGYGHYTGIDLAEERSGNMPTREWKQKRFKKPWYQGDTIP
                     VGIGQGYWTATPIQMSKALMILINDGIVKVPHLLMSTAEDGKQVPWVQPHEPPVGDIH
                     SGYWELAKDGMYGVANRPNGTAHKYFASAPYKIAAKSGTAQVFGLKANETYNAHKIAE
                     RLRDHKLMTAFAPYNNPQVAVAMILENGGAGPAVGTLMRQILDHIMLGDNNTDLPAEN
                     PAVAAAEDH"
     gene            10342..11454
                     /gene="mrdB"
                     /locus_tag="RHX21_002779"
                     /gene_synonym="rodA"
     CDS             10342..11454
                     /gene="mrdB"
                     /locus_tag="RHX21_002779"
                     /gene_synonym="rodA"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004885876.1"
                     /note="rod shape-determining protein RodA; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase MrdB"
                     /protein_id="HDV1987938.1"
                     /translation="MTDNPNKKTFWDKVHLDPTMLLILLALLVYSALVIWSASGQDIG
                     MMERKIGQIAMGLVIMVVMAQIPPRVYEGWAPYLYIICIILLVAVDAFGAISKGAQRW
                     LDLGIVRFQPSEIAKIAVPLMVARFINRDVCPPSLKNTGIALVLIFMPTLLVAAQPDL
                     GTSILVALSGLFVLFLSGLSWRLIGVAVVLVAAFIPILWFFLMHDYQRQRVMMLLDPE
                     SDPLGAGYHIIQSKIAIGSGGLRGKGWLHGTQSQLEFLPERHTDFIFAVLAEELGLVG
                     ILILLALYILLIMRGLWIAARAQTTFGRVMAGGLMLILFVYVFVNIGMVSGILPVVGV
                     PLPLVSYGGSALIVLMAGFGIVMSIHTHRKMLSKSV"
     gene            11465..12553
                     /gene="rlpA"
                     /locus_tag="RHX21_002780"
     CDS             11465..12553
                     /gene="rlpA"
                     /locus_tag="RHX21_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic peptidoglycan transglycosylase RlpA"
                     /protein_id="HDV1987939.1"
                     /translation="MRKQWLGICIAAGMLAACTSDDGQQQTVSVPQPAVCNGPIVEIS
                     GADPRFEPLNATANQDYQRDGKSYKIVQDPSRFSQAGLAAIYDAEPGSNLTASGEAFD
                     PTQLTAAHPTLPIPSYARITNLANGRMIVVRINDRGPYGNDRVISLSRAAADRLNTSN
                     NTKVRIDPIIVAQDGSLSGPGMACTTVAKQTYALPAPPDLSGGAGASSVSGPQGDILP
                     VSNSTLKSEDPTGAPVTSSGFLGAPTTLAPGVLESSEPTPAPQPVVTAPSTTPATSPA
                     MVTPQAASQSASGNFMVQVGAVSDQARAQQYQQQLGQKFGVPGRVTQNGAVWRIQLGP
                     FASKAEASTLQQRLQTEAQLQSFITTAQ"
     gene            12693..13904
                     /gene="dacA"
                     /locus_tag="RHX21_002781"
     CDS             12693..13904
                     /gene="dacA"
                     /locus_tag="RHX21_002781"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase DacA"
                     /protein_id="HDV1987940.1"
                     /translation="MNTIFSARIMKRLALTTALCTAFISAAHADDLNIKTMIPGVPQI
                     DAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGN
                     DAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVG
                     LMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFT
                     FNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKG
                     REAESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIPRGRM
                     KDLKASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGNFFGKIID
                     YIKLMFHHWFG"
     gene            14015..14278
                     /locus_tag="RHX21_002782"
     CDS             14015..14278
                     /locus_tag="RHX21_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbeD family protein"
                     /protein_id="HDV1987941.1"
                     /translation="MKTKLNELLEFPTPFTYKVMGQALPELVDQVVEVVQRHAPGDYT
                     PTVKPSSKGNYHSVSITINATHIEQVETLYEELGKIDIVRMVL"
     gene            14379..15020
                     /gene="lipB"
                     /locus_tag="RHX21_002783"
     CDS             14379..15020
                     /gene="lipB"
                     /locus_tag="RHX21_002783"
                     /EC_number="2.3.1.181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415163.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl(octanoyl) transferase LipB"
                     /protein_id="HDV1987942.1"
                     /translation="MYQDKILVRQLGLQPYEPISQAMHEFTDTRDDSTLDEIWLVEHY
                     PVFTQGQAGKAEHILMPGDIPVIQSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRELV
                     TLLEQTVVNTLAELGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDL
                     SPFLRINPCGYAGMEMAKISQWKPEATTNNIAPRLLENILALLNNPDFEYITA"
     gene            15279..16232
                     /locus_tag="RHX21_002784"
     CDS             15279..16232
                     /locus_tag="RHX21_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415162.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
                     /protein_id="HDV1987943.1"
                     /translation="MDSNNQIEPCLSRKSSEGKPQIFTTLRNIDLNLLTIFEAVYVHK
                     GIVNAAKVLNLTPSAISQSIQKLRVIFPDPLFIRKGQGVTPTAFAMHLHEYISQGLES
                     ILGALDIEGSYDKQRTITIATTPSVGALVLPVIYRAIKTHYPQLLLRNPPISDAENQL
                     SQFQTDLIIDNMFCTNRTVQHHVLFTDNMVLICREGNPLLSLEDDRETIDNAAHVLLL
                     PEEQNFSGLRQRVQEMFPDRQINFTSYNILTIAALVANSDMLAIIPSRFYNLFSRCWP
                     LEKLPFPSLNEEQIDFSIHYNKFSLRDPILHGVRDVIRNAF"
     gene            16441..17406
                     /gene="lipA"
                     /locus_tag="RHX21_002785"
     CDS             16441..17406
                     /gene="lipA"
                     /locus_tag="RHX21_002785"
                     /EC_number="2.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl synthase"
                     /protein_id="HDV1987944.1"
                     /translation="MSKPIVMERGVKYRDADKMALIPVKNVATEREALLRKPEWMKIK
                     LPADSTRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCD
                     VAHGRPVAPDANEPVKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIREKS
                     PQIKIETLVPDFRGRMDRALDILTATPPDVFNHNLENVPRIYRQVRPGADYNWSLKLL
                     ERFKEAHPEIPTKSGLMVGLGETNEEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQ
                     RYVSPDEFDEMKAEALAMGFTHAACGPFVRSSYHADLQAKGMEVK"
     gene            complement(17507..17710)
                     /gene="tatE"
                     /locus_tag="RHX21_002786"
     CDS             complement(17507..17710)
                     /gene="tatE"
                     /locus_tag="RHX21_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase subunit TatE"
                     /protein_id="HDV1987945.1"
                     /translation="MGEISITKLLVVAALVVLLFGTKKLRTLGGDLGAAIKGFKKAMN
                     DDDAAAKKGADVDLQAEKLSHKE"
     gene            complement(17839..18627)
                     /locus_tag="RHX21_002787"
     CDS             complement(17839..18627)
                     /locus_tag="RHX21_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deaminated glutathione amidase"
                     /protein_id="HDV1987946.1"
                     /translation="MLVAAGQFAVTSVWEKNAEICASLMAQAAENDVSLFVLPEALLA
                     RDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAG
                     NIVARYAKLHLYDAFAIQESRRVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA
                     LQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPF
                     GVTIAAASEMPALIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL"
     gene            18720..19103
                     /gene="crcB"
                     /locus_tag="RHX21_002788"
     CDS             18720..19103
                     /gene="crcB"
                     /locus_tag="RHX21_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HDV1987947.1"
                     /translation="MLQLLLAVFIGGGTGSVARWLLSMRFNPLHQAIPLGTLAANLIG
                     AFIIGMGFAWFSRMTNIDPVWKVLITTGFCGGLTTFSTFSAEVVFLLQEGRFGWALLN
                     VFVNLLGSFAMTALAFWLFSASTAH"
     gene            complement(19158..19367)
                     /gene="cspE"
                     /locus_tag="RHX21_002789"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
     CDS             complement(19158..19367)
                     /gene="cspE"
                     /locus_tag="RHX21_002789"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator/RNA stability
                     regulator CspE"
                     /protein_id="HDV1987948.1"
                     /translation="MSKIKGNVKWFNESKGFGFITPEDGSKDVFVHFSAIQTNGFKTL
                     AEGQRVEFEITNGAKGPSAANVIAL"
     gene            complement(19542..20102)
                     /gene="pagP"
                     /locus_tag="RHX21_002790"
     CDS             complement(19542..20102)
                     /gene="pagP"
                     /locus_tag="RHX21_002790"
                     /EC_number="2.3.1.251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A) palmitoyltransferase PagP"
                     /protein_id="HDV1987949.1"
                     /translation="MNVSKYVAIFSFVFIQLISVGKVFANADEWMTTFRKNIAQTWQQ
                     PEHYDLYIPAITWHARFAYDKEKTDRYNERPWGGGFGLSRWDEKGNWHGLYAMAFKDS
                     WNKWEPIAGYGWESTWRPLADENFHLGLGFTAGVTARDNWNYIPLPVLLPLASVGYGP
                     VTFQMTYIPGTYNNGNVYFAWMRFQF"
     gene            20690..22075
                     /gene="dcuC"
                     /locus_tag="RHX21_002791"
     CDS             20690..22075
                     /gene="dcuC"
                     /locus_tag="RHX21_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuC"
                     /protein_id="HDV1987950.1"
                     /translation="MLTFIELLIGVVVIVGVARYIIKGYSATGVLFVGGLLLLIISAI
                     MGHKVLPSSQASTGYSATDIVEYVKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDMV
                     VKLASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRG
                     AAAAICASPAAIILAPTSGDVVLAAQASEMSLIDFAFKTTLPISIAAIIGMAIAHFFW
                     QRYLDKKEHISHEMLDVSEITTTAPAFYAILPFTPIIGVLIFDGKWGPQLHIITILVI
                     CMLIASILEFLRSFNTQKVFSGLEVAYRGMADAFANVVMLLVAAGVFAQGLSTIGFIQ
                     SLISIATSFGSASIILMLVLVILTMLAAVTTGSGNAPFYAFVEMIPKLAHSSGINPAY
                     LTIPMLQASNLGRTLSPVSGVVVAVAGMAKISPFEVVKRTSVPVLVGLVIVIVATELM
                     VPGTAAAVTGK"
     gene            complement(22116..22796)
                     /gene="dpiA"
                     /locus_tag="RHX21_002792"
                     /gene_synonym="citB"
     CDS             complement(22116..22796)
                     /gene="dpiA"
                     /locus_tag="RHX21_002792"
                     /gene_synonym="citB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component response regulator DpiA"
                     /protein_id="HDV1987951.1"
                     /translation="MTAPLTLLIVEDETPLAEMHAEYIRHIPGFSQILLAGNLAQARM
                     MIERFKPGLILLDNYLPDGRGINLLHELVQAHYPGDVVFTTAASDMETVSEAVRCGVF
                     DYLIKPIAYERLGQTLTRFRQRKHMLESIDSASQKQIDEMFNAYARGEPKDELPTGID
                     PLTLNAVRKLFKEPGVQHTAETVAQALTISRTTARRYLEYCASRHLIIAEIVHGKVGR
                     PQRIYHSG"
     gene            complement(22765..24423)
                     /gene="dpiB"
                     /locus_tag="RHX21_002793"
     CDS             complement(22765..24423)
                     /gene="dpiB"
                     /locus_tag="RHX21_002793"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase DpiB"
                     /protein_id="HDV1987952.1"
                     /translation="MLQLNENKQFAFFQRLAFPLRIFLLILVFSIFVIAALAQYFTAS
                     FEDYLTLHVRDMAMNQAKIIASNDSVISAVKTRDYKRLATIADKLQRDTDFDYVVIGD
                     RHSIRLYHPNPEKIGYPMQFTKQGALEKGESYFITGKGSMGMAMRAKTPIFDDDGKVI
                     GVVSIGYLVSKIDSWRAEFLLPMAGVFVVLLGILMLLSWFLAAHIRRQMMGMEPKQIA
                     RVVRQQEALFSSVYEGLIAVDPHGYITAINRNARKMLGLSSPGRQWLGKPIAEVVRPA
                     DFFTEQIDEKRQDVVANFNGLSVIANREAIRSGDDLLGAIISFRSKDEISTLNAQLTQ
                     IKQYVESLRTLRHEHLNWMSTLNGLLQMKEYDRVLAMVQGESQAQQQLIDSLREAFAD
                     RQVAGLLFGKVQRARELGLKMIIVPGSQLSQLPPGLDSTEFAAIVGNLLDNAFEASLR
                     SDEGNKIVELFLSDEGDDVVIEVADQGCGVPESLRDKIFEQGVSTRADEPGEHGIGLY
                     LIASYVMRCGGVITLEDNDPCGTLFSIYIPKVKPNDSSINPIDR"
BASE COUNT         6139 a         6181 c         6060 g         6102 t
ORIGIN      
        1 tatttatact tttctgacgc gacataatac gcataaaata aggcttacgc aaaaatggaa
       61 cacataaaaa tataatatgt tttatctgca accataagga aatgataatg attttcacgt
      121 caagttgctg cgataattta tcaatagatg agattatcga acgtgctgaa aaaggcgatt
      181 gcgaggctca atatattgtt gggttttatt ataatcgcga tagcgcaatt gattctccgg
      241 acgacgaaaa agccttttac tggctgaagc tgtccgctga gcaaggtcat tgtgaagcac
      301 agtattcctt agggcaaaag tataccgagg ataaaagccg tcataaagat aatgagcaag
      361 ccatcttctg gctgaaaaaa gctgccctac aaggccatac tttcgcttcc aacgcccttg
      421 gctggacact ggatcgtgga gaagccccca attataaaga agcggttgtc tggtatcaga
      481 tagccgcgga gagcggaatg tcttatgcgc aaaataatct tgggtggatg tacagaaatg
      541 gcaacggagt cgcaaaagac tatgcgctgg catttttctg gtacaaacaa gctgcattac
      601 aaggccatag tgacgcgcaa aacaatctgg ccgatcttta tgaagacgga aaaggcgttg
      661 ctcaaaacaa gacactcgcc gcattctggt atttgaaaag cgcacagcag ggtaatcggc
      721 acgcccagtt tcaaattgca tgggattata acgctggcga aggggtggac caggactata
      781 agcaagcgat gtactggtat ctgaaggctg ccgctcagga aagcgtcggc gcttacgtca
      841 acatcggtta tatgtataaa cacggacaag gcgttgagaa agattatcag gctgcctttg
      901 aatggtttac gaaagccgct gaatgcaatg acgccactgc ctggtataac ctggccatta
      961 tgtatcacta cggagaagga agacctgtcg atctccgaca ggctctcgac ctgtatcgta
     1021 aagttcagtc atccggaacc agagatgtca gtcaggaaat tcgtgagact gaagatttac
     1081 tgtagagata aaaacaaggg ccggggaatt tcattcggcc catattctct ttattgctgt
     1141 gcgaaatcag actattacgg ctcaaacggg cgtctctgga actggtcatg accacatttc
     1201 gggcatagcg tcagcacttc cggtgtgtag atcgggagat ggaagtgaca tttctcgcag
     1261 accagatttc ccagcccgac cacttctccg ctgtgataaa ccccatgatg attgaggtcc
     1321 tggaaaactt cgcgccattc aagctgcgtt ttatcggtga tatctgccag ctcctgccat
     1381 aagctttctt taatcacccg cataaagacg ctgtcagatt cttctttcag gctctcttca
     1441 tagctcatgg cgaactcttc caggtcacgt cttacagctc gcgtcagctc atcgacctcg
     1501 gttcgcgtta actcccctgt ttttattacg cgctcgcgcg cctgttccac cagtgcgtcg
     1561 atatcacgtt cgccattgcg caggcgttcg ctcagtgacg cgaccagttc acggtaatat
     1621 tgagcaacct tgttcatcgt ttcatctccc gggtcgttaa ctgactataa taatagacgt
     1681 tctttgttcc ttgctttgct aatacgccca caaactctgt aaattaatgt atgaataatc
     1741 cgggcatcat ttcaacgtcg agtgcgcgaa aggctgtttt gacgcggacg tttgggctat
     1801 gctatgcgga tctgaaaaac cacctcaacg ctacatttgt agccgtattg aaaacaggac
     1861 cactggctgc catgcaagag caataccgcc cggaagagat agaatccaaa gtacagcttc
     1921 attgggatga gaagcgcaca tttgaagtaa ccgaagacga gagcaaagag aagtattact
     1981 gcctgtctat gcttccctat ccttctggtc gactacacat gggccacgta cgtaactaca
     2041 ccatcggtga cgtgatcgcc cgctaccagc gtatgctggg caaaaacgtc ctgcagccga
     2101 tcggctggga cgcgtttggt ctgcctgcgg aaggcgcggc ggtgaaaaac aacaccgctc
     2161 cggcaccgtg gacgtacgac aacatcgcgt atatgaaaaa ccagctcaaa atgctgggct
     2221 ttggttatga ctggagccgc gagctggcaa cctgtacgcc ggaatactac cgttgggaac
     2281 agaaattctt caccgagctg tataaaaaag gcctggtata taagaagact tctgcggtca
     2341 actggtgccc gaacgaccag accgtactgg cgaacgaaca agttatcgac ggctgctgct
     2401 ggcgctgcga taccaaagtt gaacgtaaag agatcccgca gtggtttatc aaaatcactg
     2461 cttacgctga cgagctgctc aacgatctgg ataaactgga tcactggcca gacaccgtta
     2521 aaaccatgca gcgtaactgg atcggtcgtt ccgaaggcgt ggagatcacc ttcaacgtta
     2581 acgactatga caacacgctg accgtttaca ctacccgccc ggacaccttt atgggttgta
     2641 cctacctggc ggtagctgcg ggtcatccgc tggcgcagaa agcggcggaa aataatcctg
     2701 aactggcggc ctttattgac gaatgccgta acaccaaagt tgccgaagct gaaatggcga
     2761 cgatggagaa aaaaggcgtc gatactggct ttaaagctgt tcacccatta acgggcgaag
     2821 aaattcccgt ttgggcagca aacttcgtat tgatggagta cggcacgggc gcagttatgg
     2881 cggttccggg tcacgaccag cgcgactacg agtttgcctc taaatacggc ctgaacatca
     2941 aaccagttat cctggctgct gacggctctg agccagatct ttctcagcaa gccctgactg
     3001 aaaaaggcgt gctgttcaac tctggcgaat tcaacggtct tgaccatgaa gcggccttca
     3061 acgccatcgc cgataaactg actgcgatgg gcgttggcga gcgtaaagtg aactaccgcc
     3121 tgcgcgactg gggtgtttct cgtcagcgtt actggggcgc gccgattccg atggtgacgc
     3181 tggaagacgg taccgtaatg ccgaccccgg acgaccagct gccggtgatc ctgccggaag
     3241 atgtggtgat ggacggcatt accagcccga ttaaagcaga tccggagtgg gcaaaaacta
     3301 ccgttaacgg tatgccagcg ctgcgtgaaa ccgacacttt cgacaccttt atggagtcct
     3361 cctggtacta tgcgcgctac acttgcccag agtacaaaga aggtatgctg gattccgaag
     3421 cggctaacta ctggctgccg gtggatatct acattggtgg tatcgaacac gccattatgc
     3481 acctgctcta cttccgcttc ttccacaaac tgatgcgtga tgcaggcatg gtgaactctg
     3541 acgaaccagc gaaacagttg ctgtgtcagg gtatggtgct ggcagatgcc ttctactatg
     3601 ttggcgaaaa cggcgaacgt aactgggttt ccccggttga tgctatcgtt gaacgtgacg
     3661 agaaaggccg tatcgtgaaa gcgaaagatg cggcaggcca tgaactggtt tataccggca
     3721 tgagcaaaat gtccaagtcg aagaacaacg gtatcgaccc gcaggtgatg gttgaacgtt
     3781 acggcgcgga caccgttcgt ctgtttatga tgtttgcttc tccggctgat atgactctcg
     3841 aatggcagga atccggtgtg gaaggggcta accgcttcct gaaacgtgtc tggaaactgg
     3901 tttacgagca cacagcaaaa ggtgatgttg cggcactgaa cgttgatgcg ctgactgaag
     3961 atcagaaagc gctgcgtcgc gatgtgcata aaacgatcgc taaagtgacc gatgatatcg
     4021 gccgtcgtca gaccttcaac accgcaattg cggcgattat ggagctgatg aacaaactgg
     4081 cgaaagcacc aaccgatggc gagcaggatc gcgctctgat gcaggaagcg ctgctggccg
     4141 ttgtccgtat gcttaacccg ttcaccccgc acatctgctt cacgctgtgg caggaactga
     4201 aaggcgaagg cgatatcgac aacgcgccgt ggccggttgc tgacgaaaaa gcgatggtgg
     4261 aagactccac gctggtcgtg gtgcaggtta acggtaaagt ccgtgccaaa atcaccgttc
     4321 cggtggacgc aacggaagaa caggttcgcg aacgtgctgg ccaggaacat ctggtagcaa
     4381 aatatcttga tggcgttact gtgcgtaaag tgatttacgt accaggtaaa ctcctcaatc
     4441 tggtcgttgg ctaagcgcgg gaggaagcgt gcgatatctg gcaacattgt tgttatctct
     4501 ggcggtgtta atcaccgccg ggtgtggctg gcatctgcgt gataccacgc aggttccttc
     4561 cactatgaag gtcatgatcc tggactcagg cgatccgaac gggccattaa gccgtgcggt
     4621 gcgtaaccag ttacgtctga atggtgtcga gttgcttgat aaagaaacca cgcgtaagga
     4681 cgttccatcc ctgcgtttgg gtaaagtgag catcgcgaaa gataccgcat cggtattccg
     4741 taacggtcaa acagcagagt atcagatgat catgacggtg aatgcgaccg tgttgatccc
     4801 cggccgtgat atctacccga ttagtgccaa agtcttccgt tcgttctttg ataacccgca
     4861 aatggcgtta gcgaaagata acgaacaaga catgatcgta aaagagatgt acgaccgtgc
     4921 tgccgaacag ctgattcgta agctgccaag catccgtgct gcggatattc gttccgacga
     4981 agaacagacg tcgaccacaa cggatactcc ggcaacgcct gcacgcgtct ccaccacgct
     5041 gggtaactga tgattcggtt gtacccggaa caactccgcg cgcagctcaa tgaagggctg
     5101 cgcgcggcgt atcttttact tggtaacgat cctctgttat tgcaggaaag ccaggacgct
     5161 gttcgtcagg tagctgcggc acaaggattc gaagaacacc acactttttc cattgatccc
     5221 aacactgact ggaatgcgat cttttcgtta tgccaggcta tgagtctgtt tgccagtcga
     5281 caaacgctat tgctgttgtt accagaaaac ggaccgaatg cggcgatcaa tgaacaactt
     5341 ctcacactca ccggacttct gcatgacgac ctgctgttga tcgtccgcgg taataaatta
     5401 agcaaagcgc aagaaaatgc cgcctggttt actgctcttg cgaatcgcag cgtgcaggtg
     5461 acctgtcaga caccggagca ggctcagctt ccccgctggg ttgctgcgcg cgcaaaacag
     5521 ctcaacttag aactggatga cgctgcaaat caggtgctct gctactgtta tgaaggtaac
     5581 ctgctggcgc tggctcaggc actggagcgt ttatcgctgc tctggccaga cggcaaattg
     5641 acattaccgc gcgttgaaca ggcggtgaat gatgccgcgc atttcacccc ttttcattgg
     5701 gttgatgctt tgttgatggg aaaaagtaag cgcgcgttgc atattcttca gcaactgcgt
     5761 ctggaaggca gcgagccggt tattttgttg cgcacattac aacgtgaact gttgttactg
     5821 gttaacctga aacgccagtc tgcccatacg ccactgcgtg cgttgtttga taagcatcgg
     5881 gtatggcaga accgccgggg catgatgggc gaggcgttaa atcgcttaag ccagccgcag
     5941 ttacgtcagg ccgtgcaact cctgacacga acggaactca ccctcaaaca agattacggt
     6001 cagtcagtgt gggcagagct ggaagggtta tctcttctgt tgtgccataa acccctggcg
     6061 gacgtattta tcgacggttg atatgaaatc tttacaggct ctgtttggcg gcacctttga
     6121 tccggtgcac tatggtcatc ttaaacccgt ggaaacgctg gcgaatttga ttggtctgac
     6181 gcgggtcaca atcatcccta ataatgttcc tccgcatcgt ccccagccgg aagcgaacag
     6241 cgtgcagcgt aaacacatgc ttgaactggc gattgccgac aagccattat ttactcttga
     6301 tgaacgcgag ctaaagcgca atgccccctc ttacactgcg caaacactga aagagtggcg
     6361 gcaggaacaa gggccggacg tgccgctggc gtttattatt ggtcaggatt cattgctgac
     6421 ctttccgacc tggtacgaat acgaaacgat actcgacaat gcacatttga tcgtctgtcg
     6481 gcgtccaggt tacccacttg aaatggcgca accgcaatac cagcaatggc tggaagatca
     6541 tttgacacat aacccggaag atcttcacct tcagcctgcc ggtaaaattt atctggctga
     6601 aacgccgtgg tttaacatct cggcgaccat catccgcgaa cgtttgcaaa acggtgaatc
     6661 gtgtgaggat ttattgccgg aaccggtact gacttacatt aaccaacaag gcttgtatcg
     6721 ctgatacctg tcgttacgga gggcatgatg cgactgtggt taattcgtca tggcgaaacg
     6781 caagcgaatg tcgatggtct gtacagcggt catgcgccca cacccctgac cgcacgcggt
     6841 attgagcaag cgcaaaatct gcatacgctg ctacatggtg tttcctttga tctggtttta
     6901 tgcagtgaac tggaacgggc acagcatacc gcgcgactgg ttctcagtga ccgccagctc
     6961 cccgtgcaaa tcatccctga actcaacgaa atgttttttg gcgactggga gatgcgacat
     7021 catcgcgacc tcatgcaaga agatgccgaa aactatagcg cgtggtgcaa tgactggcag
     7081 catgcaatcc ccacgaacgg tgaaggattt caggcatttt cgcaacgtgt ggaacgcttt
     7141 atcgcaaggc ttagtgaatt tcagcactat cagaatattt tagtcgtcag ccatcagggt
     7201 gtactgagtc tgttaatcgc ccgtttaatt ggcatgcctg ccgaggctat gtggcatttt
     7261 cgcgttgacc aggggtgttg gagcaccatt gatatcaacc aaaaattcgc gacgctacgc
     7321 gtcctcaata gccgtgccat cggggtcgag aatgcatgac ttttctgttt ttttacgggt
     7381 aagccgcaac gaccattgac agacccgggc aggctgatat tctccgcagc cagacttttt
     7441 tcgccagaca cgactttgta gaaattgttt tacaaaaatg gcgatgcaat ctgcggcgcg
     7501 gggtgggatg atagcccact ttcgaaagcc gattcggcga caattgtccc gaaatcgcct
     7561 ctggttcagg tatactgaca gaccattttt atctatttga ttcacccagg gggaaaactt
     7621 gcagggtaaa gcactccagg attttgttat cgacaaaatt gatgacctca aaggtcagga
     7681 catcatcgcc ttagacgttc aaggcaaatc cagcatcacc gactgcatga tcatctgtac
     7741 gggtacgtcc agccgtcatg ttatgtccat tgctgaccac gttgtgcagg agtctcgcgc
     7801 agcgggcctg ttaccgctcg gcgtagaagg tgaaaaccgc gccgactgga ttgtcgtgga
     7861 tttgggcgat gtgattgtcc atgtcatgca ggaagagagc cgtcgcctgt atgaactgga
     7921 aaaactctgg agttaatgcg tgaagctgca acttgtcgcc gtgggaacga aaatgccgga
     7981 ctgggtacaa accggtttta ccgagtacct gcgtcgtttt ccgaaagata tgcccttcga
     8041 gctgattgaa attccggccg gaaaacgcgg caagaatgcg gacatcaagc gcatactcga
     8101 caaagagggt gagcagatgt tggcggccgc aggcaaaaac cgcattgtca ccctcgatat
     8161 tccaggcaag ccctgggata cgccgcagtt agccgctgag ctggaacgct ggaagctgga
     8221 tggtcgcgac gtcagtctac tgattggcgg gcctgaaggg ttgtcgcctg cctgtaaagc
     8281 ggcggcggag cagagctggt cgctgtcggc gcttaccctc ccccatccgc tggttcgcgt
     8341 gctggtcgca gagagtctgt accgggcgtg gagcatcacc accaaccatc cttatcaccg
     8401 tgagtgataa gggagctttg agtagaaaac gcagcggatg aaactacaga actcttttcg
     8461 cgactatacg gcagagtccg cgctgtttgt gcgccgggcg ctggtcgcct ttttggggat
     8521 tttgctgctg accggcgtgc ttatcgccaa cctgtataat ctgcaaattg ttcgctttac
     8581 cgactaccag actcgctcta atgaaaaccg cattaagctg gtgcctatcg cgcccagccg
     8641 cggcattatc tacgaccgta atggtatccc tctggccctc aaccgcacta tctaccagat
     8701 agaaatgatg ccagagaaag tcgataacgt gcagcaaacg ctggacgctt tgcgcagcgt
     8761 ggttgatctg accgatgacg atattgctgc attccgaaaa gagcgcgcac gttcacaccg
     8821 tttcacctct attccggtga aaactaacct gaccgaagta caagtagctc gctttgccgt
     8881 caatcagtac cgttttccgg gtgtcgaagt taaaggctat aaacgtcgtt actatcctta
     8941 cggttcggcg ttgacccacg tcatcggcta tgtgtcgaaa atcaacgata aagacgtcga
     9001 acgcctgaat aatgacggca aactggccaa ctatgcggca acgcatgata tcggtaagct
     9061 gggcattgag cgttactatg aagacgtgct gcacggtcag accggttatg aagaggttga
     9121 agttaacaac cgtgggcgtg ttatccgcca gttaaaagaa gtaccaccgc aagccggaca
     9181 cgatatttac ctgacgctgg atctcaaact ccagcaatat attgaaacgc tgctggcggg
     9241 tagccgcgca gctgtggttg tcaccgatcc gcgtacaggt ggggtgctgg cgctggtttc
     9301 cacgcctagt tatgacccaa acctgtttgt tgacggtatc tccagcaaag attattccgc
     9361 cttgttgaac gacccgaata caccgctggt gaaccgcgcc acacaggggg tttatcctcc
     9421 cgcgtctaca gttaaaccct atgtggcggt ttcggcattg agcgccgggg tgatcacgcg
     9481 caatacgacg ctgtttgacc caggctggtg gcaactgcca ggttcggaaa aacgttatcg
     9541 tgactggaaa aaatggggcc acgggcgtct gaatgtcaca agatcgctgg aagaatctgc
     9601 ggataccttc ttctatcagg tggcctacga tatggggatc gatcgcctct ccgaatggat
     9661 gggtaaattc ggttatggtc attacaccgg tatcgacctg gcggaagaac gttccggcaa
     9721 catgcctacc cgcgaatgga aacagaaacg ctttaaaaaa ccgtggtatc agggtgacac
     9781 cattccggtt ggtatcggtc agggttactg gacagcgacc ccaatccaga tgagtaaggc
     9841 actgatgatc ctgattaatg acggtatcgt gaaggttcct catttgctga tgagcaccgc
     9901 cgaagacggc aaacaggtgc catgggtaca gccgcatgaa ccgcccgtcg gcgatattca
     9961 ttccggttac tgggagctgg cgaaagacgg tatgtacggt gttgctaacc gccctaacgg
    10021 tacggcgcat aaatactttg ccagcgcacc gtacaaaatt gcggcgaaat ccggtaccgc
    10081 tcaggtcttc ggtctgaaag cgaacgaaac ctataatgcg cacaaaattg ccgagcgttt
    10141 acgtgaccac aaactgatga ccgcctttgc gccatacaac aatccgcaag tggctgtcgc
    10201 catgattctg gagaacggtg gtgcgggtcc ggcggttggg acactgatgc gccagatcct
    10261 cgaccacatt atgctgggtg ataacaacac cgatctgcct gcggaaaatc cagcggttgc
    10321 cgcagcggag gaccattaat catgacggat aatccgaata aaaaaacatt ctgggataaa
    10381 gtccatctcg atcccacaat gctgctgatc ttactggcat tgctggttta cagcgccctg
    10441 gttatctgga gcgccagcgg tcaggatatt ggcatgatgg agcgtaaaat cggccaaatc
    10501 gcgatgggtc tggtcatcat ggtggtgatg gcgcaaattc ctccacgcgt ttatgaaggc
    10561 tgggccccct atctctatat catctgtatt attttgctgg tggcggtaga tgctttcggt
    10621 gccatctcta aaggtgctca acgctggctg gacctcggta ttgttcgttt tcagccgtcg
    10681 gaaattgcca aaatagccgt accactgatg gttgcgcgct ttatcaaccg cgacgtttgc
    10741 ccgccatcgt tgaagaacac tggcatcgcg ctggtgctga tatttatgcc cacgctgctg
    10801 gtggctgcac agcctgacct gggaacatca atcctcgttg cgctttccgg tctgtttgta
    10861 ctgttcctct ctggccttag ctggcgtctg attggcgtcg cagtagtgct ggtggcggcg
    10921 ttcattccga ttctgtggtt cttcctgatg catgattacc agcgccagcg cgtaatgatg
    10981 ctcctggacc cggaatcaga cccactcggc gcgggctatc acattattca gtctaaaatt
    11041 gctattggct ccggcggatt acgcggcaaa ggctggctgc atggcactca gtcacaactt
    11101 gaatttctac ccgaacgcca taccgacttt atcttcgcgg tactggcgga agagctggga
    11161 ttagtgggca ttctgattct gctcgctctc tacattctgc tgatcatgcg cgggctgtgg
    11221 atagccgcca gagcgcaaac cacctttggt cgcgtcatgg ctggcggctt aatgctgata
    11281 ttattcgttt atgtcttcgt aaatattggt atggtaagcg gtattctgcc ggttgtaggg
    11341 gttccgctcc cactggtcag ttatggagga tcagcgctaa ttgtgctgat ggctgggttc
    11401 gggattgtaa tgtcaatcca cacccacagg aaaatgttgt cgaaaagcgt gtaagaggtg
    11461 cgcaatgcgt aagcagtggc tcgggatctg catcgcggca ggaatgctcg cggcatgtac
    11521 aagcgatgat ggtcagcaac agacggtaag tgtaccgcag cctgcggtat gtaacggccc
    11581 catagttgaa attagcgggg cggacccgcg tttcgaacca ctgaacgcga cggcaaatca
    11641 ggattaccag cgcgacggta aaagctacaa aatcgtgcag gatccgtctc gatttagcca
    11701 ggcgggactg gcggcaatct atgatgccga accaggcagt aacctgacgg cctctggcga
    11761 agctttcgat ccgacacagt tgacggcggc ccatccaacg cttccgatcc ccagctacgc
    11821 cagaatcact aacctggcta acgggcgaat gatcgtggtg cgcattaatg atcgcggccc
    11881 ctacggcaac gaccgcgtaa tttcgctttc tcgcgcagca gctgaccgtc ttaacacgtc
    11941 aaacaacacc aaagttcgta tcgatccgat tattgtcgcc caggatggtt cgctttctgg
    12001 tcctggtatg gcttgtacca cagtcgccaa acagacttac gccctgcctg cacctcccga
    12061 tttaagcggt ggcgcggggg caagttcagt gtctggcccg cagggtgaca ttcttccggt
    12121 cagtaactcg acgctaaaaa gcgaagatcc gaccggcgcg ccggtaacca gtagcggttt
    12181 cctcggcgct ccaacgacct tagcgcctgg tgtactggaa agcagcgaac cgacacctgc
    12241 accacagccc gttgttacag ctccgtcgac aacgcctgca acctcgcctg caatggtgac
    12301 accgcaagcc gcctcgcaaa gcgccagcgg caactttatg gtgcaagtcg gggccgttag
    12361 cgatcaggct cgtgcgcaac agtaccaaca gcaactggga cagaagttcg gcgtccccgg
    12421 tcgcgtaact caaaatggcg cggtctggcg tatccagctt ggcccattcg ccagtaaagc
    12481 cgaagccagt accttgcagc aacgtttgca aaccgaagcc caattacagt catttattac
    12541 caccgcgcag tagcgtaaag caggcatctg atgtgtcaat ttctgtaaat gacgttaaca
    12601 aagtcacgcg gaaagtcaga tgcctgccgg tagtgcattt gctatagtag ggcacttttt
    12661 ttaattccat cacggatgtc gtagttcaga ccatgaatac cattttttcc gctcgtatca
    12721 tgaagcgcct ggcgctcacc acggctcttt gcacagcctt tatctctgct gcacatgccg
    12781 atgacctgaa tatcaaaact atgatcccgg gtgtaccgca gatcgatgcg gagtcctaca
    12841 tcctgattga ctataactcc ggcaaagtgc tcgccgaaca gaacgcagat gtccgccgcg
    12901 atcctgccag cctgaccaaa atgatgacca gttacgttat cggccaggca atgaaagccg
    12961 gtaaatttaa agaaactgat ttagtcacta tcggcaacga cgcatgggcc accggtaacc
    13021 cggtgtttaa aggttcttcg ctgatgttcc tcaaaccggg catgcaggtt ccggtttctc
    13081 agctgatccg cggtattaac ctgcaatcgg gtaacgatgc ttgcgtcgcc atggccgatt
    13141 ttgccgctgg tagccaggac gcttttgttg gcttgatgaa cagctacgtt aacgccctgg
    13201 gcctgaaaaa cacccacttc cagacggtac atggtctgga tgctgatggt cagtacagct
    13261 ccgcgcgaga tatggcgctg atcggccagg cattgatccg tgacgtaccg aatgaatact
    13321 cgatctataa agaaaaagaa tttacgttta acggtattcg ccagctgaac cgtaacggcc
    13381 tgttatggga taacagcctg aatgtcgacg gcatcaaaac cggacacact gacaaagcag
    13441 gttacaacct tgttgcttct gcgactgaag gccagatgcg cttgatttct gcggtgatgg
    13501 gcggacgtac ttttaaaggc cgtgaagccg aaagtaaaaa actgctaacc tggggcttcc
    13561 gtttcttcga aaccgttaac ccactgaaag taggtaaaga gttcgcctct gaaccggttt
    13621 ggtttggtga ttctgatcgc gcttcgttag gggttgataa agacgtgtac ctgaccattc
    13681 cacgtggtcg catgaaagat ctgaaagcca gctatgtgct gaacagcagt gaattgcatg
    13741 cgccgctgca aaagaatcag gtcgtcggaa ctatcaactt ccagcttgat ggcaaaacga
    13801 tcgagcaacg cccgctggtt gtgttgcaag aaatcccgga aggtaacttc ttcggcaaaa
    13861 tcattgatta cattaaatta atgttccatc actggtttgg ttaaaaattg aacacttgaa
    13921 agtgtaattt ccgtccccat atactaagca tcagtaaaaa aactcccgcc ttctggcggg
    13981 agttgctatt taattacgtt acgccggagc tgacatgaaa accaaactta acgaactgct
    14041 tgaattccct actcctttta cttacaaagt tatggggcag gcgttacctg agctggttga
    14101 tcaggtggtt gaagtggtac agcgccatgc gccaggtgac tacaccccaa cggtaaaacc
    14161 aagcagcaaa ggcaactacc actcggtatc tatcactatc aacgccactc atatcgagca
    14221 ggttgaaaca ctgtatgaag aactgggcaa aatcgatatt gtccgcatgg ttctgtaact
    14281 cgcttctccg ttacccggct cctggtcggg taactcccct ctcctcgctg tgatatactt
    14341 ttcccccact tttactcatt ctccacggag atgccgtttt gtatcaggat aaaattcttg
    14401 tccgccagct cggtcttcag ccttacgagc caatctccca ggctatgcat gaattcaccg
    14461 atacccgcga tgatagtacc cttgatgaaa tctggctggt cgagcactat ccggtattca
    14521 cccaaggtca ggcaggaaaa gcggagcaca ttttaatgcc gggtgatatt ccggtgatcc
    14581 agagcgatcg cggtgggcag gtgacttatc acgggccggg acaacaggtg atgtatgtgt
    14641 tgcttaacct gaaacgccgt aaactcggtg tgcgtgaact ggtgaccttg cttgagcaaa
    14701 cagtggtgaa taccctggct gaactgggta tagaagcgca tcctcgggct gacgcgcctg
    14761 gtgtctatgt cggggaaaag aaaatttgct cactgggttt acgaattcga cgcggttgtt
    14821 cattccacgg tctggcatta aacgtcaata tggatctttc accattttta cgtattaatc
    14881 cttgtgggta tgccggaatg gaaatggcta aaatatcaca atggaaaccc gaagcgacga
    14941 ctaataatat tgctccacgt ttactggaaa atattttagc gctactaaac aatccggact
    15001 tcgaatatat taccgcttaa ttccatacat caatggccca atttacactg ggtcattact
    15061 cataatacct gctaatgctt tacatctcct tcgcgtttgt atattttctt tatcacttgc
    15121 agaaatgcgg tgccacgcct tgctccgcaa ctcaccccat tgattaacct attgaaatag
    15181 ttgattatgg tgagcaaaag cgttccgttc caattagaca taagattatt gtaatttttt
    15241 aaatattatt tttccatgaa taaaattgga gtaagtgcgt ggatagtaat aatcaaattg
    15301 aaccctgttt aagcagaaag tcgtcagaag gtaaaccaca aatatttaca accttacgaa
    15361 atattgatct taaccttctg actatttttg aagctgtata tgtacataaa gggatcgtta
    15421 atgcagcgaa agtgcttaat ctgaccccct cggcaatcag tcagtctatt cagaaactgc
    15481 gcgttatatt ccctgaccca ttgtttattc gcaaaggcca gggtgtcact cctaccgcat
    15541 ttgcgatgca tctacatgag tatatcagtc agggccttga gtccattctt ggcgcgctgg
    15601 atatcgaagg aagctatgat aagcaacgaa cgataactat tgcgaccact ccctcggtcg
    15661 gagccctggt ccttcctgtc atctatcggg cgattaaaac tcactatccg cagcttttac
    15721 tgcgcaaccc gcccatcagc gacgcggaaa accaactcag tcagtttcaa accgatctca
    15781 tcatcgataa catgttttgc accaatcgta cggtgcaaca tcatgttctg ttcaccgaca
    15841 atatggtgtt aatttgccgc gagggaaatc cactactctc tttagaagat gacagagaga
    15901 ctatcgacaa cgctgcgcat gtacttctgt taccggaaga gcaaaatttc agcggtctgc
    15961 ggcagagagt tcaagaaatg tttccggacc ggcaaatcaa tttcaccagc tacaacattt
    16021 tgacaatcgc tgcactggtt gccaacagtg acatgttagc gattattccc agccgttttt
    16081 ataacctgtt tagccgctgc tggccgctgg aaaaactgcc ttttccgtcc ttaaatgagg
    16141 agcaaataga tttctctatc cactacaaca aattcagcct gcgtgatccc atcctgcacg
    16201 gagtaagaga tgttatccgt aatgcatttt gaaaaagtat tgttacagcc agatcacagc
    16261 gcagaacgat aaaatggcac aatccaacaa caattttaca ttttcgcgac cgctttggct
    16321 gctttcaggt ccgtttcaat gatatactgc cagtcgttaa ttcaaaaata gttgataatt
    16381 acaacaatct attgaattga aacgctttcc ttcgtaattc gcaactggaa cacgcacgct
    16441 atgagtaaac ccattgtgat ggaacgcggt gttaaatacc gcgatgccga taagatggcc
    16501 cttatcccgg ttaaaaacgt ggcaacagag cgcgaagccc tgctgcgcaa gccggaatgg
    16561 atgaaaatta agcttccagc ggactctaca cgtatccagg gcatcaaagc cgcaatgcgc
    16621 aaaaatggcc tgcattctgt ctgcgaggaa gcctcctgcc ctaacctggc ggaatgcttc
    16681 aaccacggca cagcaacgtt tatgatcctc ggcgctattt gtacccgccg ttgtccgttc
    16741 tgtgatgttg cccacggtcg cccggtagct cctgatgcca atgaaccagt gaaactggcg
    16801 cagaccattg ccgatatggc gctgcgttat gtggttatca cctccgttga ccgtgatgac
    16861 ctgcgcgatg gcggtgccca gcactttgcg gattgcatta ctgccattcg ggaaaaaagc
    16921 ccgcaaatca aaattgaaac tctggtgccg gatttccgtg gtcgtatgga tcgtgctctg
    16981 gatattctga ctgcaacgcc accagatgtg ttcaaccata acctggaaaa cgtaccgcgt
    17041 atttaccgtc aggtacggcc tggtgcagat tacaactggt cgctgaagct gctggaacgc
    17101 tttaaagaag cgcatccgga aatcccgacc aagtctggtc tgatggtggg actgggtgaa
    17161 accaatgaag aaattattga ggtaatgcgc gacctgcgcc gtcatggtgt gacgatgtta
    17221 acgctggggc aatatttgca gccaagccgc catcacctgc cggttcaacg ttacgttagc
    17281 ccggatgagt tcgacgaaat gaaagccgaa gcgctggcga tgggctttac ccatgctgca
    17341 tgcggtccgt ttgtccgctc ttcttaccac gccgatttgc aggcgaaagg gatggaagtt
    17401 aagtaatcct gtaataatta cttacatctg tctgataaaa aacccgcttt ttgaagcggg
    17461 ttttttgtat cgaacaagat attgagggag cgtcctgctc gccacgtcac tctttatgag
    17521 agagcttttc agcctgaaga tcaacgtctg cgcctttttt cgccgcagca tcgtcatcat
    17581 tcatcgcctt cttgaaccct ttaatggccg ctccaaggtc tccgcccagc gtacgtaact
    17641 tcttagtccc aaacagcaga acgaccagcg ccgcaactac tagcagtttg gtaatactaa
    17701 tctcacccat agataccttc ttgacatata accggcaaca gaacgcgcct taaaaaccag
    17761 agaatattaa cggtcattcg acgcgcgcac acaatagcaa tctgtaacaa ggtgaatcaa
    17821 gcgccgagta aaaaaacatc ataataattg cggcggcgca aagcgacggt tgtttaagac
    17881 gggcagttgc gcgcgcacct gacgcacacg ttcgggcgtc acttccgcca taatgagtgc
    17941 aggcatttct gacgctgccg caatggtgac gccaaaggga tctataatcc ggctttgacc
    18001 gatatttttg ttcccgcact cccccgccgc caccatataa caggtggtat ccagcgcacg
    18061 agcggcaagc aacgttgacc agtgatgctc tttgagcggc ccgcgaaccc aggcggcagg
    18121 aagtaccagg atttcagctc cctgtaatgc ctgtgccagc gccagctctg gaaagcgtaa
    18181 gtcataacag gtcatcagac cgaccttcat cccctccacc tcgagtaacg gagcgatttc
    18241 attaccagca tcaacacggc gtgattcctg aatggcaaat gcatcataga gatgcaattt
    18301 ggcataacgg gcgacgatgt ttcctgcctg tagcgccacc agcatattcc atgcgcgccc
    18361 cggcgttgaa ggaacatgaa tcgtcagaat tgtcgtcatc atgttacgtt tactttctcg
    18421 ccgtaaacgt ccgaggaatt cgccttccag cagctgtgct gatttaaccg atagatctgc
    18481 atcatgatca tcgcgcgcca gcaatgcttc cggcaggacg aacagcgata cgtcgttttc
    18541 cgccgcctgc gccatcaacg aggcacaaat ctcagcgttc ttttcccaca cagatgtaac
    18601 agcaaactgt cctgcggcaa ccagcattgc cacctcctgt cagagtcgta aaattcgcca
    18661 acgacgatta ttcggcgtta cacttatcac tcatacaaat caaatagcag gattttgcag
    18721 tgttacaact tcttttagca gtttttattg gcggtggtac gggaagcgtg gcgagatggc
    18781 tgttaagtat gcgatttaac ccgctgcatc aggcgattcc gttggggacg ctggcagcaa
    18841 acctgattgg ggcattcatc ataggaatgg gattcgcatg gttcagcagg atgacgaaca
    18901 ttgatccagt gtggaaagta ttaatcacca ccggattttg tggcggtcta acaaccttct
    18961 caacattttc ggcagaagtg gtgtttttgt tacaagaggg tcgctttggc tgggcattac
    19021 tgaacgtttt cgtcaacctt ctggggtctt ttgccatgac agcactggct ttctggctgt
    19081 tttcggcctc aaccgcacac taaagaccaa aaaaaaaccc gctgattaag cgggttttga
    19141 attcttgctg acgtatctta cagagcgatt acgtttgcag cagaagggcc tttggcaccg
    19201 ttagtgattt cgaactctac gcgctgacct tcagcaagag ttttaaaacc attagtctgg
    19261 attgcagaga agtgtacgaa cacgtctttg ctgccgtctt ccggagtaat gaaaccgaat
    19321 cctttggact cattaaacca cttaacgtta cctttaatct tagacatcaa aattaccttt
    19381 acatgaaaaa tagacacaaa tgctgtgtcg gttaccagta caccaattgt ggtacgcttt
    19441 gtccagtgca actttactaa aaagtgataa aagtcgcgtt atttttgatg ttacttattt
    19501 tagctattga ttttaaagaa gttactaaaa cttcatttgt ctcaaaactg aaagcgcatc
    19561 caggcaaagt acacattgcc attgttgtag gtacccggaa tgtaggtcat ctgaaaagtc
    19621 actgggccat aacccacgga ggccaatggc agtagaaccg ggagagggat gtaattccag
    19681 ttatcgcgtg ccgttacgcc agcggtgaat cccagaccta aatgaaaatt ttcatccgcc
    19741 agcggtcgcc aggtactttc ccatccgtat ccggcaatcg gttcccattt gttccacgag
    19801 tccttaaatg ccatggcata caggccatgc cagtttcctt tttcatccca acgcgacagg
    19861 ccaaaaccgc caccccacgg tcgctcgtta tagcgatcgg ttttttcttt gtcgtaagcg
    19921 aaacgtgcat gccaggtgat ggcaggaata tataaatcat aatgttcagg ctgttgccag
    19981 gtttgtgcaa tattttttct aaacgttgtc atccactcat ctgcgttagc aaaaacttta
    20041 ccaacgctga ttaactgaat aaaaacaaag gaaaagatag cgacatattt actcacgttc
    20101 atttgtgacc ataaaacatt tatcaaaaat ctactactag catagcaaag ctacaattaa
    20161 cataacctta atagacccaa cataaagaat aatctgaata gctgctcatt tatttccgct
    20221 tgttcaagtt aaatatttcc gcgcatcgat taaagatgat gcgtcgtttt ctgcgatggg
    20281 aatagtcaaa aaagaaaaac caagtctttt ttgatgacaa aatgcaatca aggaaaaatt
    20341 attttatttt ttaacgagat acaacaatca tcttaacgaa gtatataata tatatcgtca
    20401 acctgtgctc atattagatt attttttgag cgcacagccg cagctaacac cattgcaatt
    20461 aacaaatttg catcaatcca ccatcaattt gcacacatta ttatgtgata attgccaacc
    20521 gctaaatatg cgttttgtta tctatgtata aaaacagcaa cttcaatgtc ttaatggcag
    20581 tttttcttga ttttaatcag cattcatcga caatttattg ggcatatttt ttccttaagc
    20641 tttaggaatt ttttattatt tactttgggg cctggagaca ggaaaaatta tgctgacatt
    20701 cattgaactc cttattgggg ttgtggttat tgtgggtgta gctcgctaca tcattaaagg
    20761 gtattccgcc actggtgtgt tatttgtcgg tggcctgtta ttgctgatta tcagtgccat
    20821 tatggggcac aaagtgttac cgtccagcca ggcttcaaca ggctacagcg ccacggatat
    20881 cgttgaatac gttaaaatat tactaatgag ccgcggcggc gacctcggca tgatgattat
    20941 gatgctgtgt ggatttgccg cttacatgac ccatatcggc gcgaatgata tggtggtcaa
    21001 gctggcgtca aaaccattgc agtatattaa ctccccttac ctgctgatga ttgccgccta
    21061 ttttgtcgcc tgtctgatgt ctctggccgt ctcttccgca accggtctgg gtgttttgct
    21121 gatggcaacc ctatttccgg tgatggtaaa cgttggtatc agtcgtggcg cagctgctgc
    21181 catttgtgcc tccccggcgg cgattattct cgcaccgact tcaggggatg tggtgctggc
    21241 ggcgcaagct tccgaaatgt cgctgattga cttcgccttc aaaacgacgc tgcctatctc
    21301 aattgctgca attatcggca tggcgatcgc ccacttcttc tggcaacgtt atctggataa
    21361 aaaagagcac atctctcatg aaatgttaga tgtcagtgaa atcaccacca ctgctcctgc
    21421 gttttatgcc attttgccgt tcacgccgat catcggtgta ctgatttttg acggtaaatg
    21481 gggtccgcaa ttacacatca tcactattct ggtgatttgt atgctgattg cctccattct
    21541 ggagttcctc cgcagcttta atacccagaa agttttctct ggtctggaag tggcttatcg
    21601 cgggatggca gatgcgtttg ctaacgtggt gatgctgctg gttgccgctg gggtattcgc
    21661 tcaggggctt agcaccatcg gctttattca aagtctgatt tctatcgcta cctcgtttgg
    21721 ttcagcgagt atcatcctga tgctggtatt ggtgattctg accatgctgg cggcagtcac
    21781 gaccggttca ggcaatgcgc cgttttatgc gtttgttgag atgatcccga aactggcgca
    21841 ctcttccggc attaacccgg cgtatttgac tatcccgatg ctgcaggcgt caaacctggg
    21901 tcgtacccta tcacccgttt ctggcgtagt cgttgcggtt gccgggatgg cgaaaatctc
    21961 accatttgaa gtcgtaaaac gcacctcggt gccggtgctt gttgggctag tgattgttat
    22021 cgttgctaca gagctgatgg tgccaggaac ggcagcagcg gtcacaggca agtaaatagt
    22081 aatgccggag gcaagtttcc tccggctttt tcatgtcacc cactgtggta tatacgttgc
    22141 ggtctgccaa ctttgccgtg aacaatttca gcaataatca gatggcggct ggcgcaatat
    22201 tcaagataac gcctggcagt ggtgcggctg atggtcagtg cctgcgccac cgtttctgcc
    22261 gtatgttgca caccaggctc tttgaacagt tttcgcaccg cgtttagcgt caaagggtca
    22321 atgccggtcg gtagctcgtc cttaggttca ccgcgagcat aagcattaaa catctcatca
    22381 atttgcttct ggctggcgct atcaatactt tccagcatat gtttacgctg gcggaaacgg
    22441 gttagcgttt gccccagccg ttcataggca atgggcttaa tgagataatc aaatacacca
    22501 caacgtacgg cttcagacac cgtttccata tcgctggctg cagtggtaaa caccacgtcg
    22561 ccgggataat gcgcctgcac cagttcatgc agtaaattaa tccctctacc gtcaggaaga
    22621 tagttatcga gcaagattag ccccggctta aaacgctcga tcatcattcg ggcctgcgcc
    22681 aggtttcccg ccagtaatat ctgactgaat ccgggaatgt gacgaatata ttccgcatgc
    22741 atctctgcca gcggcgtttc gtcctcaacg atcaataggg ttaatggagc tgtcattagg
    22801 tttcactttc ggaatataga ttgaaaataa ggtaccgcag ggatcattat cttcgagagt
    22861 gataacacca ccgcagcgca ttacgtagct ggcaatcaag tacaacccaa tgccatgttc
    22921 accgggctcg tcagcacgcg tactgacccc ctgctcaaat attttgtctc gtagagactc
    22981 tggaacgccg cagccctgat cggcgacttc aatcaccaca tcatcgcctt catcgctgag
    23041 gaataattca acgatcttgt ttccttcatc gctacgcagg ctggcttcga aggcgttatc
    23101 aagtaaattg ccaacaatgg cggcaaactc ggtgctatcc agtcctggcg gcagttgcga
    23161 aagctggcta ccggggacga tgatcatttt tagccccagt tcgcgggcgc gctgcacttt
    23221 accaaaaagc agccccgcca cctggcgatc ggcaaacgcc tcgcgcaggc tgtcaataag
    23281 ctgttgctgg gcctgagact ccccctgcac catcgccagc acgcgatcat actctttcat
    23341 ctgcaacaga ccattgagcg tcgacatcca attgagatgc tcgtgtcgca atgtacgaag
    23401 gctctcaacg tattgtttta tttgcgtcag ttgcgcattg agggtggaaa tttcgtcttt
    23461 actacgaaag ctgataatgg cccccagcaa atcatcacct gaacgaatag cttcccggtt
    23521 ggcaataacg ctcagaccgt taaagttcgc caccacatcc tgacgttttt catcaatctg
    23581 ttcggtaaag aaatcggcgg gcctgaccac ttcagcaatg ggtttaccca accattgccg
    23641 tccaggggaa ctcagcccca gcatctttct tgcgttacga ttgatggcgg taatgtaacc
    23701 gtgcggatcc accgcaatca gcccttcata aaccgaacta aacagcgcct cttgctgacg
    23761 gaccacccgt gcgatttgct ttggctccat gcccatcatc tgccgacgga tatgcgcggc
    23821 caggaaccac gacagcaaca tcagaatccc taacagcacg acaaacacgc ctgccatcgg
    23881 taataaaaac tcagcccgcc agctatcgat tttactcacc aggtagccaa tcgacaccac
    23941 gccgatgact tttccatcgt catcaaagat tggcgttttg gcgcgcatcg ccatacccat
    24001 tgaccctttc ccggtaatga agtagctctc ccctttctcc agcgcgccct gtttggtgaa
    24061 ctgcatagga taaccaattt tctccggatt aggatggtaa aggcggatcg agtgccggtc
    24121 gccaatcacc acataatcaa aatcggtatc tctttgtaat ttgtcagcga tggtcgccag
    24181 ccgtttgtag tcacgcgttt tcaccgcaga gatgacactg tcattggagg caataatttt
    24241 cgcctgattc attgccatgt cgcgtacatg aagcgttaaa tagtcctcaa aactggccgt
    24301 aaaatattgc gccagggctg caatgacaaa tattgagaac accagaatca gcaaaaagat
    24361 acgcagcgga aatgccagtc tttggaaaaa tgcaaactgt ttattctcgt taagctgcaa
    24421 cattgttttc cttgcgggtt gtcccgagcc tctttgacgg atgtaattaa aatgttgaat
    24481 ca
//
LOCUS       DAPGUL010000064        24417 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.064, whole genome shotgun sequence.
ACCESSION   DAPGUL010000064 DAPGUL010000000
VERSION     DAPGUL010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24417)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24417)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24417
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.064"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            211..894
                     /locus_tag="RHX21_002794"
     CDS             211..894
                     /locus_tag="RHX21_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3251 domain-containing protein"
                     /protein_id="HDV1987953.1"
                     /translation="MNLKKIFFSAVTVSVLCALTGCDYIEEGKPESSLLKQQEEHNNK
                     IDLLEKQQAQLKSQLETIQKQQTGIISSTKTLTHVIKSVKDQQNTFIFTEFNPAKTKY
                     FILNNGSVALAGRVLSIDATENGSVIHISLVNLLSTPISNIGFNATWGGEKPVDAKEF
                     ARWQQLLFNTSMKSTLKLLPGQWQDINLTLKGVSPNNLGYLKLAINMENIQFDNLPSA
                     ENRQKRSKK"
     gene            938..5788
                     /gene="ehaG"
                     /locus_tag="RHX21_002795"
     CDS             938..5788
                     /gene="ehaG"
                     /locus_tag="RHX21_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric autotransporter adhesin EhaG"
                     /protein_id="HDV1987954.1"
                     /translation="MNKIFKVIWNPATGNYTVTSETAKSRGKKSGRSKLLISALVAGG
                     MLSSFGALANAGNDNGQGVDYGSGSAGDGWVAIGKGAKANTFMNTSGSSTAVGYDAIA
                     EGQYSSAIGSKTHAIGGASMAFGVSAISEGDRSIALGASSYSLGQYSMALGRYSKALG
                     KLSIAMGDSSKAEGANAIALGNATKATEIMSIALGDTANASKAYSMALGASSVASEEN
                     AIALGRSSVASGTDSLAFGRQSLASAANAIAIGAETEAAENATAIGNNAKAKGTNSMA
                     MGFGSLADKVNTIALGNGSQALADNAIAIGQGNKADGVDAIALGNGSQSRGLNTIALG
                     TASNATGDKSLALGSNSSANGINSVALGADSIADLDNTVSVGNSSLKRKIVNVKNGAI
                     KSDSYDAINGSQLYAISDSVAKRLGGGAAVDVDDGTVTAPTYNLKNGSKNNVGAALAV
                     LDENTLQWDQTKGKYSAAHGTSSPTASVITDVADGTISASSKDAVNGSQLKATNDDVE
                     ANTANIATNTSNIATNTANIATNTTNITNLTDSVGDLQADALLWNETKKAFSAAHGQD
                     TTSKITNVKDADLTADSTDAVNGSQLKTTNDAVATNTTNIANNTSNIATNTTNISNLT
                     ETVTNLGEDALKWDKDNGVFTAAHGTETTSKITNVKDGDLTTGSTDAVNGSQLKTTND
                     AVATNTTNIATNTTNISNLTETVTNLGEDALKWDKDNGVFTAAHGNNTASKITNILDG
                     TVTATSSDAINGSQLYDLSSNIATYFGGNASVNTDGVFTGPTYKIGETNYYNVGDALA
                     AINSSFSTSLGDALLWDATAGKFSAKHGTNGDASVITDVADGEISDSSSDAVNGSQLH
                     GVSSYVVDALGGGAEVNADGTITAPTYTIANADYDNVGDALNAIDTTLDDALLWDADA
                     GENGAFSAAHGKDKTASVITNVANGAISAASSDAINGSQLYTTNKYIADALGGDAEVN
                     ADGTITAPTYTIANAEYNNVGDALDALDDNALLWDETANGGAGAYNASHDGKASIITN
                     VANGSISEDSTDAVNGSQLNATNMMIEQNTQIINQLAGNTDATYIQENGAGINYVRTN
                     DDGLAFNDASAQGVGATAIGYNSVAKGDSSVAIGQGSYSDVDTGIALGSSSVSSRVIA
                     KGSRDTSITENGVVIGYDTTDGELLGALSIGDDGKYRQIINVADGSEAHDAVTVRQLQ
                     NAIGAVATTPTKYFHANSTEEDSLAVGTDSLAMGAKTIVNGDKGIGIGYGAYVDANAL
                     NGIAIGSNAQVIHVNSIAIGNGSTTTRGAQTNYTAYNMDAPQNSVGEFSVGSADGQRQ
                     ITNVAAGSADTDAVNVGQLKVTDAQVSQNTQSITNLNNQVTNLDTRVTNIENGIGDIV
                     TTGSTKYFKTNTDGVDASAQGKDSVAIGSGSIAAADNSVALGTGSVATEENTISVGSS
                     TNQRRITNVAAGKNDTDAVNVAQLKSSEAGGVRYDTKADGSIDYSNITLGGGNGGTTR
                     ISNVSAGVNNNDAVNYAQLKQSVQETKQYTDQRMVEMDNKLSKTESKLSGGIASAMAM
                     TGLPQAYTPGASMASIGGGTYNGESAVALGVSMVSANGRWVYKLQGSTNSQGEYSAAL
                     GAGIQW"
     gene            6156..7811
                     /gene="lldP"
                     /locus_tag="RHX21_002796"
     CDS             6156..7811
                     /gene="lldP"
                     /locus_tag="RHX21_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
                     /protein_id="HDV1987955.1"
                     /translation="MNLWQQNYDPAGNIWLSSLIASLPILFFFFALIKLKLKGYVAAS
                     WTVAIALAVALLFYKMPVANALASVVYGFFYGLWPIAWIIIAAVFVYKISVKTGQFDI
                     IRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFKPLYAAGLC
                     LIVNTAPVAFGAMGIPILVAGQVTGIDSFEIGQMVGRQLPFMTIIVLFWIMAIMDGWR
                     GIKETWPAVVVAGGSFAIAQYLSSNFIGPELPDIISSLVSLLCLTLFLKRWQPVRVFR
                     FGDLGASQVDMTLAHTGYTAGQVLRAWTPFLFLTATVTLWSIPPFKALFASGGALYEW
                     VINIPVPYLDKLVARMPPVVSEATAYAAVFKFDWFSATGTAILFAALLSIVWLKMKPS
                     DAISTFGSTLKELALPIYSIGMVLAFAFISNYSGLSSTLALALAHTGHAFTFFSPFLG
                     WLGVFLTGSDTSSNALFAALQATAAQQIGVSDLLLVAANTTGGVTGKMISPQSIAIAC
                     AAVGLVGKESDLFRFTVKHSLIFTCMVGVITTLQAYVLTWMIP"
     gene            7811..8587
                     /gene="lldR"
                     /locus_tag="RHX21_002797"
     CDS             7811..8587
                     /gene="lldR"
                     /locus_tag="RHX21_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LldR"
                     /protein_id="HDV1987956.1"
                     /translation="MIVLPRRLSDEVADRVRALIDEKNLEAGMKLPAERQLAMQLGVS
                     RNSLREALAKLVSEGVLLSRRGGGTFIRWRHDTWSEQNIVQPLKTLMADDPDYSFDIL
                     EARYAIEASTAWHAAMRATPGDKEKIQLCFEATLSEDPDIASQADVRFHLAIAEASHN
                     IVLLQTMRGFFDVLQSSVKHSRQRMYLVPPVFSQLTEQHQAVIDAIFAGDADGARKAM
                     MTHLSFVHTTMKRFDEDQARHARITRLPGEHYEHSREKNA"
     gene            8584..9774
                     /gene="lldD"
                     /locus_tag="RHX21_002798"
     CDS             8584..9774
                     /gene="lldD"
                     /locus_tag="RHX21_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent L-lactate dehydrogenase"
                     /protein_id="HDV1987957.1"
                     /translation="MIISAASDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSE
                     VALRQRILKNMSDLSLETTLFNEKLSMPVALAPVGLCGMYARRGEVQAAKAADAHGIP
                     FTLSTVSVCPIEEVAPAIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPT
                     PGARYRDAHSGMSGPNAAMRRYLQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLE
                     DYIGWLGNNFDPSISWKDLEWIRDFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHG
                     GRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAFLY
                     ALATAGQAGVANLLNLIEKEMKVAMTLTGAKSISEITQDSLVQGLGKELPAALAPMAK
                     GNAA"
     gene            9928..10401
                     /gene="trmL"
                     /locus_tag="RHX21_002799"
     CDS             9928..10401
                     /gene="trmL"
                     /locus_tag="RHX21_002799"
                     /EC_number="2.1.1.-"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HDV1987958.1"
                     /translation="MLNIVLYEPEIPPNTGNIIRLCANTGFRLHIIEPMGFAWDDKRL
                     RRAGLDYHEFTAVTRHHDFRAFLEAENPQRLFALTTKGTPAHSAVSYQDGDYLMFGPE
                     TRGLPASILDALPAEQKIRIPMVPDSRSMNLSNAVSVVVYEAWRQLGYPGALLRD"
     gene            complement(10454..11275)
                     /gene="cysE"
                     /locus_tag="RHX21_002800"
     CDS             complement(10454..11275)
                     /gene="cysE"
                     /locus_tag="RHX21_002800"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HDV1987959.1"
                     /translation="MSCEELEIVWNNIKAEARTLADCEPMLASFYHATLLKHENLGSA
                     LSYMLANKLSSPIMPAIAIREVVEEAYAADPEMIASAACDIQAVRTRDPAVDKYSTPL
                     LYLKGFHALQAYRIGHWLWNQGRRALAIFLQNQVSVTFQVDIHPAAKIGRGIMLDHAT
                     GIVVGETAVIENDVSILQSVTLGGTGKSGGDRHPKIREGVMIGAGAKILGNIEVGRGA
                     KIGAGSVVLQPVPPHTTAAGVPARIVGKPDSDKPSMDMDQHFNGINHTFEYGDGI"
     gene            complement(11355..12374)
                     /gene="gpsA"
                     /locus_tag="RHX21_002801"
     CDS             complement(11355..12374)
                     /gene="gpsA"
                     /locus_tag="RHX21_002801"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDV1987960.1"
                     /translation="MNQRNASMTVIGAGSYGTALAITLARNGHEVVLWGHDPEHIATL
                     ERDRCNAAFLPDVPFPDTLHLESDLATALAASRNILVVVPSHVFGEVLRQIKPLMRPD
                     ARLVWATKGLEAETGRLLQDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTD
                     QTFADDLQQLLHCGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTAL
                     ITRGLAEMSRLGAALGADPATFMGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVQSA
                     QEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLGRARKD
                     ERSSH"
     gene            complement(12374..12841)
                     /gene="secB"
                     /locus_tag="RHX21_002802"
     CDS             complement(12374..12841)
                     /gene="secB"
                     /locus_tag="RHX21_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015369180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HDV1987961.1"
                     /translation="MSEQNNTEMTFQIQRIYTKDISFEAPNAPHVFQKDWQPEVKLDL
                     DTASTQLADDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSIAGIEGTQMAHCLGAYC
                     PNILFPYARECITSMVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA"
     gene            complement(12904..13155)
                     /gene="grxC"
                     /locus_tag="RHX21_002803"
     CDS             complement(12904..13155)
                     /gene="grxC"
                     /locus_tag="RHX21_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 3"
                     /protein_id="HDV1987962.1"
                     /translation="MANVEIYTKETCPYCHRAKALLSSKGVSFQELPIDGNAAKREEM
                     IKRSGRTTVPQIFIDAQHIGGCDDLYALDARGGLDPLLK"
     gene            complement(13296..13727)
                     /locus_tag="RHX21_002804"
     CDS             complement(13296..13727)
                     /locus_tag="RHX21_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDV1987963.1"
                     /translation="MQEIMQFVGRHPILSIAWIALLVAVLVTTFKSLTSKVKVISRGE
                     ATRLINKEDAVVVDLRQRDDFRKGHIAGSINLLPSEIKANNVGELEKHKDKPVIVVDG
                     SGLQCQEPANALTKAGFAQVFVLKEGVAGWAGENLPLVRGK"
     gene            13972..15516
                     /gene="gpmM"
                     /locus_tag="RHX21_002805"
                     /gene_synonym="pgmI"
     CDS             13972..15516
                     /gene="gpmM"
                     /locus_tag="RHX21_002805"
                     /gene_synonym="pgmI"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HDV1987964.1"
                     /translation="MSVSKKPMVLVILDGYGYREEQQDNAIFSAKTPVMDALWANRPH
                     TLIDASGLEVGLPDRQMGNSEVGHVNLGAGRIVYQDLTRLDVEIKDRAFFANPVLTGA
                     VDKAKNAGKAVHIMGLLSAGGVHSHEDHIMAMVELAAERGAEKIYLHAFLDGRDTPPR
                     SAESSLKKFEEKFAALGKGRVASIIGRYYAMDRDNRWDRVEKAYDLLTLAQGEFQADT
                     AVAGLQAAYARDENDEFVKATVIRAEGQPDAAMEDGDALIFMNFRADRAREITRAFVN
                     ADFDGFARKKVVNVDFVMLTEYAADIKTAVAYPPASLVNTFGEWMAKNDKTQLRISET
                     EKYAHVTFFFNGGVEESFKGEDRILINSPKVATYDLQPEMSSAELTEKLVAAIKSGKY
                     DTIICNYPNGDMVGHTGVMEAAVKAVEALDHCVEEVAKAVESVGGQLLITADHGNAEQ
                     MRDPATGQAHTAHTNLPVPLIYVGDKNVKAVEGGKLSDIAPTMLSLMGMEIPQEMTGK
                     PLFIVE"
     gene            15526..16809
                     /gene="envC"
                     /locus_tag="RHX21_002806"
     CDS             15526..16809
                     /gene="envC"
                     /locus_tag="RHX21_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein hydrolase activator EnvC"
                     /protein_id="HDV1987965.1"
                     /translation="MRGKAINTMTRAVKPRRFAIRPIIYASVLSAGVLLCAFSAHADE
                     RDQLKSIQADIAAKERAVRQKQQQRASLLAQLKKQEEAISEATRKLRETQNTLNQLNK
                     QIDEMNASIAKLEQQKAAQERSLAAQLDAAFRQGEHTGIQLILSGEESQRGQRLQAYF
                     GYLNQARQETIAQLKQTREEVAMQRAELEEKQSEQQTLLYEQRAQQAKLTQALNERKK
                     TLAGLESSIQQGQQQLSELRANESRLRNSIARAEAAAKARAEREAREAQAVRDRQKEA
                     TRKGTTYKPTESEKSLMSRTGGLGAPRGQAFWPVRGPTLHRYGEQLQGELRWKGMVIG
                     ASEGTEVKAIADGRVILADWLQGYGLVVVVEHGKGDMSLYGYNQSALVSVGSQVRAGQ
                     PIALVGSSGGQGRPSLYFEIRRQGQAVNPQPWLGR"
     gene            16813..17772
                     /locus_tag="RHX21_002807"
     CDS             16813..17772
                     /locus_tag="RHX21_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312519.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent polysaccharide deacetylase family
                     protein"
                     /protein_id="HDV1987966.1"
                     /translation="MFPFRRNVLAFAALLALSSPVLAGKLAIVIDDFGYRPHNENQVL
                     AMPSAISVAVLPDSPHAREMATKAHNSGHEVLIHLPMAPLSKQPLEKNTLRPEMSSDE
                     IERIIRSAVNNVPYAVGINNHMGSKMTSNLFGMQKVMQALERYNLYFLDSVTIGNTQA
                     MRAAQGTGVKVIKRKVFLDDSQNEADIRVQFNRAIDLARRNGSTIAIGHPHPSTVRVL
                     QQMVYNLPPDITLVKASSLLNEPQVDTSTPPKNAVPDAPRNPFRGVKLCKPKKPIEPV
                     YANRFFEVLSESISQSTLIVYFQHQWQGWGKQPEAAKFNASAN"
     gene            complement(17759..18793)
                     /gene="waaH"
                     /locus_tag="RHX21_002808"
     CDS             complement(17759..18793)
                     /gene="waaH"
                     /locus_tag="RHX21_002808"
                     /EC_number="2.4.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate:LPS(HepIII) glycosyltransferase"
                     /protein_id="HDV1987967.1"
                     /translation="MMNSTNKLSVIIPLYNAGDDFRTCMESLITQTWTALEIIIINDG
                     STDNSVEIAKHYAENYPHVRLLHQANAGASVARNRGIEVATGKYVAFVDADDEVYPTM
                     YETLMTMALEDDLDVAQCNADWCFRETGETWQSIPSDRLRSTGVLTGPDWLRMGLSSR
                     RWTHVVWMGVYRRDVIVKNNIKFIAGLHHQDIVWTTEFMFNALRARYTEQSLYEYYLH
                     NTSVSRLHRQGNKNLNYQRHYIKITRLLEKLNRNYADKITIYPEFHQQITYEALRVCH
                     AVRKEPDILTRQRMIAEIFTSGMYKRLITNVRSVKVGYQALLWSFRLWQWRDKTRSHH
                     RITRSAFNLR"
     gene            complement(19032..20057)
                     /gene="tdh"
                     /locus_tag="RHX21_002809"
     CDS             complement(19032..20057)
                     /gene="tdh"
                     /locus_tag="RHX21_002809"
                     /EC_number="1.1.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HDV1987968.1"
                     /translation="MKALSKLKAEEGIWMTDVPVPELGHNDLLIKIRKTAICGTDVHI
                     YNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGG
                     RTHLCRNTIGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSF
                     DLVGEDVLVSGAGPIGIMAAAVAKHVGARNVVITDVNEYRLELARKMGITRAVNVAKE
                     NLNDVMAELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKV
                     IFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDDFQKGFDAMRSGQSG
                     KVILSWD"
     gene            complement(20067..21263)
                     /gene="kbl"
                     /locus_tag="RHX21_002810"
     CDS             complement(20067..21263)
                     /gene="kbl"
                     /locus_tag="RHX21_002810"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HDV1987969.1"
                     /translation="MRGEFYQQLTNDLETARAEGLFKEERIITSAQQADITVADGSHV
                     INFCANNYLGLANHPDLIAAAKAGMDSHGFGMASVRFICGTQDSHKELEQKLAAFLGM
                     EDAILYSSCFDANGGLFETLLGAEDAIISDALNHASIIDGVRLCKAKRYRYANNDMQE
                     LEARLKEAREAGARHVLIATDGVFSMDGVIANLKGVCDLADKYDALVMVDDSHAVGFV
                     GENGRGSHEYCDVMGRVDIITGTLGKALGGASGGYTAARKEVVEWLRQRSRPYLFSNS
                     LAPAIVAASIKVLEMVEAGSELRDRLWANARQFREQMSAAGFTLAGADHAIIPVMLGD
                     AVVAQKFARELQKEGIYVTGFFYPVVPKGQARIRTQMSAAHTPEQITRAVEAFTRIGK
                     QLGVIA"
     gene            21477..22409
                     /gene="rfaD"
                     /locus_tag="RHX21_002811"
     CDS             21477..22409
                     /gene="rfaD"
                     /locus_tag="RHX21_002811"
                     /EC_number="5.1.3.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-glyceromanno-heptose 6-epimerase"
                     /protein_id="HDV1987970.1"
                     /translation="MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVD
                     LDIADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLH
                     YCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANS
                     QIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVA
                     DVNLWFLENGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEYIPFPDKLKGRYQAFT
                     QADLTNLRAAGYDKPFKTVAEGVTEYMAWLNRDA"
     gene            22419..23465
                     /gene="rfaF"
                     /locus_tag="RHX21_002812"
     CDS             22419..23465
                     /gene="rfaF"
                     /locus_tag="RHX21_002812"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001685669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-heptose--LPS heptosyltransferase RfaF"
                     /protein_id="HDV1987971.1"
                     /translation="MKILVIGPSWVGDMMMSQSLYRTLQARYPQAIIDVMAPAWCRPL
                     LSRMPEVNEAIPMPLGHGALEIGERRKLGHSLREKRYDRAYVLPNSFKSALVPFFAGI
                     PHRTGWRGEMRYGLLNDVRVLDKEAWPLMVERYVALAYDKGVMRTAQDLPQPLLWPQL
                     QVSEGEKSYTCNQFSLSSERPMIGFCPGAEFGPAKRWPHYHYAELAKQLIDEGYQVVL
                     FGSAKDHEAGNEILAALNTEQQAWCRNLAGETQLDQAVILIAACKAIVTNDSGLMHVA
                     AALNRPLVALYGPSSPDFTPPLSHKARVIRLITGYHKVRKGDAAEGYHQSLIDITPQR
                     VLEELNALLLQEEV"
     gene            23469..>24417
                     /gene="rfaC"
                     /locus_tag="RHX21_002813"
     CDS             23469..>24417
                     /gene="rfaC"
                     /locus_tag="RHX21_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide heptosyltransferase RfaC"
                     /protein_id="HDV1987972.1"
                     /translation="MRVLIVKTSSMGDVLHTLPALTDAQQAIPGIKFDWVVEEGFAQI
                     PSWHAAVERVIPVAIRRWRKAWFSAPIKAERKAFREALQAENYDAVIDAQGLVKSAAL
                     VTRLAHGVKHGLDWQTAREPLASLFYNRKHHIAKQQHAVERTRELFAKSLGYSKPQTQ
                     GDYAIAQHFLTNLPTDAGEYAVFLHATTRDDKHWPEEHWRELIGLLADSGIRIKLPWG
                     APHEEERAKRLAEGFAYVEVLPKMSLEGVARVLAGAKFVVSVDTGLSHLTAALDRPNI
                     TVYGPTDPGLIGGYGKNQMVCRAPGNELSQLTANAVKRFI"
BASE COUNT         6155 a         6311 c         6319 g         5632 t
ORIGIN      
        1 taatcatcat tagaatccac gaaaaataat atattcatac aaacacagac atcttttgaa
       61 acgaatgata catttttatg atgaatgctt aaaacaatat ttaatcgaca cacatcactg
      121 tcattaatgt aaagcaacat agatcaccaa taatacaatg gacaactcta ccggcattga
      181 tcgctggtcg gaggaaataa ggatttttac atgaacttga agaagatttt tttcagtgct
      241 gtcactgttt cagttctctg cgcattaacg ggatgtgact acattgaaga aggcaagcca
      301 gaaagtagtt tattgaaaca acaagaagaa cataacaata aaattgatct acttgaaaaa
      361 caacaagcac agctaaagag tcaactggaa actattcaaa aacaacaaac tggcataata
      421 agcagtacaa agactttaac tcacgtaatt aaatccgtta aagatcaaca aaacactttt
      481 atttttaccg agtttaaccc agcaaaaacg aagtatttca tcctgaacaa tggttcggtg
      541 gctttagcgg gtcgagtgtt atccattgac gccacagaga atggcagtgt tattcatatt
      601 tcactggtca acttattaag tacacctatc tcaaatattg gttttaatgc gacatggggt
      661 ggtgaaaaac ctgtcgatgc caaagagttt gcccggtggc aacaattact tttcaacaca
      721 tcaatgaaat ccacattgaa attattacca ggtcaatggc aagacattaa tttgaccctg
      781 aagggtgtat cgcccaataa cctgggatat ctgaagttag ccatcaacat ggaaaatatt
      841 cagttcgaca atcttccctc tgctgaaaat cggcagaaaa gaagcaaaaa ataaatgcag
      901 ttagtacgct tataacaagg aatagcgagc atcattaatg aacaaaatat ttaaagttat
      961 ctggaaccct gcgacaggga attatactgt taccagcgaa acggcaaaaa gccgtggcaa
     1021 gaaatctggg cgcagtaagc tgttaatttc tgcgctggtt gcgggtggaa tgttgtcgtc
     1081 gtttggggca ttggcgaatg ccgggaatga caacggtcag ggtgttgatt acggtagtgg
     1141 atcagctggc gacggctggg ttgctatagg caaaggggcg aaagcaaata cttttatgaa
     1201 caccagtggt tccagtactg ctgtgggtta tgacgctata gctgaaggcc aatatagctc
     1261 tgccatcggg tcaaaaaccc atgcgattgg cggtgcatca atggcctttg gggttagtgc
     1321 aatatcagaa ggcgatagaa gtatagcact gggtgcctct tcgtattcat tgggccaata
     1381 ctcaatggcc ctcggccgtt attcaaaagc attgggtaaa ttgtctattg ctatggggga
     1441 ctcttccaaa gcggaaggag caaacgccat tgccctggga aatgccacta aagctactga
     1501 gattatgagt attgctcttg gcgacaccgc caatgcgtca aaagcgtatt caatggcgct
     1561 gggagcaagt agcgtcgcat ctgaagaaaa cgcaattgcc ctggggcgta gcagtgtagc
     1621 tagcggtact gacagcctcg catttggcag acaatcactt gccagcgcag cgaacgctat
     1681 tgcgataggt gctgagaccg aagccgctga aaatgcaact gctattggca ataatgcgaa
     1741 ggcaaaaggg actaatagca tggcaatggg gttcggaagc cttgccgata aagtcaatac
     1801 tatcgcatta ggaaatggca gccaggctct ggcagataat gcaatcgcca taggccaggg
     1861 caacaaagct gatggcgtgg atgccatcgc tctgggtaat ggtagccagt cgagaggctt
     1921 aaacaccatt gccttaggca cagccagtaa tgcaactggt gataagagtc ttgcgcttgg
     1981 tagtaatagc agtgccaacg gtattaactc tgtcgcgctg ggcgcagatt ccattgcgga
     2041 tttagacaat accgtctctg tcggcaatag ttcattaaaa cgcaagatcg ttaatgtgaa
     2101 aaatggcgcg atcaagtctg acagttacga tgccattaat ggttcacagc tttatgccat
     2161 tagcgactcg gtagcaaaaa ggcttggagg aggggctgca gtagatgttg atgacggtac
     2221 tgttacagca ccaacctaca atttaaaaaa tggtagcaaa aataacgtag gggctgcgct
     2281 cgctgtactt gatgaaaaca ccctgcaatg ggaccaaacc aaaggcaaat acagcgctgc
     2341 tcatggtact agtagcccaa ctgccagcgt aatcaccgat gttgcggatg gcacgatttc
     2401 agcctccagt aaggatgcgg ttaacggttc ccaactgaaa gctaccaatg acgatgtcga
     2461 agccaatacc gccaatatcg ctactaatac cagcaacatt gccacgaata cggcaaatat
     2521 tgccaccaat accaccaata tcaccaacct gacggattcc gttggtgacc ttcaggctga
     2581 tgccctgctc tggaacgaaa ctaaaaaggc attcagtgca gctcacggcc aggataccac
     2641 cagcaaaatc accaacgtta aagatgccga cctgacggct gacagcactg atgctgttaa
     2701 cggctctcag ctgaaaacca ccaacgatgc tgtggcgacg aataccacca atatcgccaa
     2761 taacacttcc aatattgcca ctaacaccac caacatctct aacctgactg agacggtgac
     2821 taatcttggt gaggatgcgc tgaaatggga taaggacaat ggtgtattca cggcagctca
     2881 tggcaccgag accaccagca aaatcaccaa cgttaaagat ggcgacctga cgactggcag
     2941 caccgatgcc gttaacggct ctcagctgaa aaccaccaac gatgccgtgg cgacgaatac
     3001 caccaatatc gccactaaca ccaccaacat ctctaatctg actgagacgg tgactaatct
     3061 tggtgaggat gcgctgaaat gggataagga caatggtgtc ttcactgcag ctcatggcaa
     3121 caataccgcc agcaaaatca ccaatatcct ggacggcaca gtcactgcaa ccagttccga
     3181 tgccattaac ggtagccagc tttatgactt aagcagcaat atcgccacct acttcggcgg
     3241 caatgcttct gtgaatactg acggtgtgtt taccggtcca acctacaaaa tcggtgaaac
     3301 aaattattat aacgtcggcg atgcactggc tgcgattaac tcctcattta gcacgtctct
     3361 cggcgatgct ctgctttggg atgccaccgc aggtaaattc agtgccaaac acggtactaa
     3421 tggtgacgca agcgtgatca ctgatgtcgc agatggtgaa atttcagact ccagttctga
     3481 cgcagtaaac ggctcacaac tccacggcgt gagcagttat gttgttgatg cgctgggagg
     3541 tggtgccgaa gtcaatgcag acggcaccat cactgcgccg acgtacacca ttgctaatgc
     3601 tgattacgat aatgtcggtg atgccctgaa tgctatcgat accactcttg acgacgctct
     3661 gctctgggat gcggacgccg gtgaaaatgg tgcatttagc gccgctcacg gaaaagataa
     3721 aactgccagt gtaatcacta acgtcgctaa cggtgcaatc tctgctgcca gcagcgacgc
     3781 gattaacggc tcacaactct ataccaccaa taagtacatc gctgatgcgc tgggtggtga
     3841 cgcagaagtc aacgctgacg gcaccatcac cgcaccgact tacaccattg cgaacgccga
     3901 gtacaacaac gtcggtgacg ccctggatgc gcttgatgat aacgccttgc tgtgggatga
     3961 gactgccaat ggcggtgctg gagcctacaa tgccagccat gacggtaaag ccagcatcat
     4021 cactaatgtc gctaatggca gtattagtga ggacagtacc gatgcagtga acggttctca
     4081 gttgaatgcg acgaatatga tgattgagca gaacacccaa attatcaatc agctcgctgg
     4141 taacaccgac gcaacctata tccaagaaaa cggtgcgggt attaactatg tgcgtactaa
     4201 cgacgacggc ttagcgttca acgacgccag cgcacagggt gttggcgcta cagctatagg
     4261 ttataactct gtcgccaaag gcgatagcag cgtagctatt ggtcagggca gctacagcga
     4321 cgttgatacg ggtatcgccc tgggtagcag ctctgtttcc agccgagtga ttgcaaaagg
     4381 ctcccgtgac accagcataa cggaaaatgg cgttgttatt ggttacgaca ccacggatgg
     4441 cgaactgctc ggtgcattgt ctatcggtga tgacggtaaa tatcgtcaaa tcatcaacgt
     4501 agccgatggt tccgaagccc atgacgccgt tacggttcgt caattgcaga atgcgattgg
     4561 tgcggtcgca accacgccga ctaaatactt ccacgctaat tcaacggaag aagattcact
     4621 ggcagtggga actgactcgc tggcaatggg tgcgaaaacc atcgtgaatg gcgataaagg
     4681 tattggtatc ggttatggtg cctacgtgga cgcgaatgca cttaacggca ttgccattgg
     4741 tagcaatgcg caagtcattc atgtcaacag tattgcgata ggtaatggtt ctacgaccac
     4801 tcgtggcgct caaaccaatt ataccgccta caacatggac gcaccgcaga actctgtcgg
     4861 tgaattctca gtcggtagtg cggatggtca acgtcagatc actaacgtcg cagcaggttc
     4921 ggctgatacc gatgcggtca acgtgggtca gttgaaagta acggatgcgc aggtttccca
     4981 gaatacccag agcattacta acctgaacaa tcaggtcact aatctggata ctcgcgttac
     5041 taatatcgaa aacggtattg gcgatatcgt caccaccggt agcaccaagt acttcaagac
     5101 caataccgat ggtgtagatg ccagcgcgca gggtaaagat agcgtcgcga ttggttctgg
     5161 ctccattgct gccgcggata acagcgtcgc actgggtaca gggtctgtgg caaccgaaga
     5221 aaatacgatc tctgtaggct catctactaa tcaacgtcgt atcaccaacg tagccgcagg
     5281 taaaaacgac accgatgctg ttaacgtggc acagttgaag tcttccgaag ctggcggtgt
     5341 gcgttacgac accaaagctg atggttctat cgactatagc aatatcaccc tcggtggcgg
     5401 caacggcggt acgactcgta tcagcaacgt ctccgctggc gtcaacaaca acgacgcggt
     5461 gaattacgcg cagttgaagc aaagcgtgca ggaaacgaag caatacaccg atcagcgaat
     5521 ggttgagatg gataacaaac tgtctaaaac tgaaagcaag ttgagcggtg gtatcgcttc
     5581 tgcaatggca atgaccggtc tgccgcaggc ttacactcca ggtgccagca tggcctctat
     5641 tggtggcggt acttacaacg gtgaatcggc agttgcttta ggtgtatcga tggtgagcgc
     5701 caatggtcgt tgggtctaca aattacaagg tagtaccaat agccagggtg aatactccgc
     5761 cgcactcggt gccggtattc agtggtaatg atccattaag ttagtgtgac taagggcaaa
     5821 cgccaaattg cctgatgcgt tacgcgcatc aggcaagata aggcgctccg ggtcaacaat
     5881 ctaagggcaa ttctctgatg aggattgccc ttttctttac cagacatctc cccccacaag
     5941 aattggccct accaattctt cgcttatctg acctctggtt cacaattccc caattaaaac
     6001 tcacatcaat attgccaata cataacattt agttaaccat tcattgtcat tatccctaca
     6061 caacacaatt ggcagtgcca cttttacaca acgtgtgaca aggagatgag caacagactc
     6121 attacacgat gtgcgtggac tccaggagac ctgcaatgaa tctctggcaa caaaactacg
     6181 atcccgccgg gaatatctgg ctttccagtc tgatagcatc gcttcccatc ctgtttttct
     6241 tctttgcgct gattaagctc aaactgaaag gatacgtcgc cgcctcatgg acggtagcaa
     6301 tcgcccttgc cgtggctttg ctgttctata aaatgccggt cgctaacgcg ctggcctcgg
     6361 tggtttatgg cttcttctat ggtttgtggc ccatcgcgtg gatcattatt gcagcagtgt
     6421 tcgtctataa gatctcggtg aaaaccgggc agtttgacat cattcgctcg tctattcttt
     6481 cgataacccc tgaccagcgt ctgcaaatgc tgatcgtcgg tttctgtttc ggcgctttcc
     6541 ttgaaggagc cgcaggcttt ggcgcaccgg tagcaattac cgccgcattg ctggtcggcc
     6601 tgggttttaa accgctgtac gccgccggac tgtgcctgat tgttaacacc gcgccagtgg
     6661 catttggcgc gatgggcatt ccaatcctgg ttgccggaca agtaacaggc atcgacagct
     6721 ttgagattgg ccagatggtg gggcggcagc taccgtttat gaccattatc gtgctgttct
     6781 ggatcatggc gattatggac ggctggcgcg gtatcaagga gacgtggcct gcggtcgtgg
     6841 ttgcgggcgg ctcgtttgcc atcgctcagt accttagctc taacttcatt gggccggagc
     6901 tgccggacat tatctcttcg ctggtatcac tgctctgcct gacgctgttc ctcaaacgct
     6961 ggcagccagt gcgcgtattc cgttttggtg atttgggggc gtcacaggtt gatatgacgc
     7021 tggcccacac cggttacact gcgggtcagg tgttacgtgc ctggacaccg ttcctgttcc
     7081 tgacagctac cgtaacactg tggagtatcc cgccgtttaa agccctgttc gcatcgggtg
     7141 gtgcgctgta tgagtgggtg atcaacattc cggtgccgta cctcgataaa ctggttgccc
     7201 gtatgccacc agtggtcagc gaggctacag cctatgccgc cgtgtttaag tttgactggt
     7261 tctctgccac cggcaccgcc attctgtttg ctgcactgct ctcgattgtc tggctgaaga
     7321 tgaaaccgtc tgacgctatc agcaccttcg gcagcacgct gaaagaactg gctctaccca
     7381 tctactccat cggcatggtg ctggcgttcg cctttatctc gaactattcc ggactgtcat
     7441 caacactggc actggcactg gcgcacaccg gtcatgcatt caccttcttc tcgccgttcc
     7501 tcggctggct gggggtattc ctgaccgggt cggatacctc atctaacgcc ctgttcgccg
     7561 cgctgcaagc caccgcagca caacaaattg gcgtctctga tctgttgctg gttgccgcca
     7621 ataccaccgg tggcgtcacc ggtaagatga tctccccgca atctatcgct atcgcctgtg
     7681 cggcggtagg cctggtgggc aaagagtctg atttgttccg ctttactgtc aaacacagcc
     7741 tgatcttcac ctgtatggtg ggcgtgatca ccacgcttca ggcttatgtc ttaacgtgga
     7801 tgattcctta atgattgttt tacccagacg cctgtcagac gaggttgccg atcgtgtgcg
     7861 ggcgctgatt gatgaaaaaa acctggaagc gggcatgaag ttgcccgctg agcgccaact
     7921 ggcgatgcaa ctcggcgtat cacgtaattc actacgcgag gcgctggcaa aactggtgag
     7981 cgaaggcgtg ctgctcagtc gacgcggcgg cgggacgttt attcgctggc gtcatgacac
     8041 atggtcggag caaaacatcg tccagccgct aaaaacgctg atggccgatg atccggatta
     8101 cagtttcgat attctggaag cccgctacgc cattgaagcc agcaccgcat ggcatgcggc
     8161 aatgcgcgcc acacctggcg acaaagaaaa gattcagctt tgctttgaag caacgctaag
     8221 tgaagacccg gatatcgcct cacaagcgga cgttcgtttt catctggcga ttgccgaagc
     8281 ctcacataac atcgtgctgc tgcaaaccat gcgcggtttc ttcgatgtcc tgcaatcctc
     8341 agtgaagcat agccgtcagc ggatgtatct ggtgccaccg gttttttcac aactgaccga
     8401 acaacatcag gctgtcattg acgccatttt tgctggtgat gccgacgggg cgcgtaaagc
     8461 aatgatgacg caccttagtt ttgttcacac caccatgaaa cgattcgatg aagatcaggc
     8521 tcgccacgca cggattaccc gcctgcccgg tgagcattat gagcattcga gggagaaaaa
     8581 cgcatgatta tttccgcagc cagcgattat cgcgccgcag cgcaacgcat tctgccgccg
     8641 ttcctgttcc actatatgga tggtggtgca tattctgaat acacgctgcg ccgcaacgtg
     8701 gaagatttgt cagaagtggc actgcgccag cgtattctga aaaacatgtc tgacttaagc
     8761 ctggaaacga cgctgtttaa tgagaaattg tcgatgccgg tagcactggc accggtgggt
     8821 ttgtgtggca tgtatgcgcg tcgtggcgaa gttcaggcag ccaaagcggc ggacgcgcat
     8881 ggcattccgt ttactctctc gacggtttcc gtttgcccga ttgaagaagt cgcgccagcc
     8941 atcaagcgcc caatgtggtt ccagctttat gtactgcgcg atcgcggctt tatgcgtaac
     9001 gcgctggagc gagcaaaagc agcgggttgt tcgacgctgg ttttcaccgt ggatatgccg
     9061 acaccgggcg cacgctaccg tgatgcgcat tcaggtatga gcggcccaaa tgcggcaatg
     9121 cgccgctact tgcaggcggt gacgcatccg caatgggcgt gggatgtggg cctgaacggt
     9181 cgtccacatg atttaggtaa tatctcagct tatctcggca aaccgaccgg actggaagat
     9241 tacatcggct ggctggggaa taacttcgat ccgtccatct catggaaaga ccttgagtgg
     9301 atccgcgatt tctgggatgg cccgatggtg atcaaaggga tcctcgatcc ggaagatgcg
     9361 cgcgatgcag tacgttttgg tgctgatgga attgtggttt ctaaccacgg tggccgccag
     9421 ctggacggtg tactctcttc cgctcgtgcg ttgcccgcta ttgcagatgc ggtgaaaggt
     9481 gatatcgcca ttctggcgga tagcggaatt cgtaacgggc ttgatgtcgt gcgtatgatt
     9541 gcgctcggtg ccgacaccgt acttctgggt cgtgctttcc tgtatgcgct ggcaacagcg
     9601 ggccaggcgg gtgtagctaa cctgctaaat ctgatcgaga aagagatgaa agtggcaatg
     9661 acgctgactg gcgcgaaatc gatcagcgaa attacgcaag attcgctggt gcaggggctg
     9721 ggtaaagagt tgcctgcggc actggccccg atggcgaaag ggaatgcggc atagtcgttt
     9781 gcgccccctc cccctaaccc tctccctcag ggagctgtct cttgatcaga tctcctgatc
     9841 aagagacagg gggaggccgg ggtgagggga aaaggccgca ctgctcacca attttctgct
     9901 atcctgcccc cgcactaagg gggcagtatg ctaaacatcg tactttacga accagaaatt
     9961 ccgccaaata ctggcaacat catccgtctt tgcgctaata ccggctttcg tctgcatatc
    10021 atcgaaccga tgggatttgc ctgggacgat aagcgcctgc gccgcgcggg gctggactat
    10081 cacgagttta ccgccgttac gcgtcatcat gactttcgcg cgttcctcga agcagaaaat
    10141 ccccagcgcc tgtttgccct caccacgaaa ggtacgcctg ctcacagcgc cgtaagctat
    10201 caggatggcg attatctgat gttcggcccg gaaacacgcg gcctgccagc gagcattctt
    10261 gatgccctgc ccgctgaaca aaaaattcgc attccgatgg tgccggacag ccgcagcatg
    10321 aacctgtcca atgcggtgtc agttgtggtg tatgaagcct ggcggcagct gggatatccg
    10381 ggagcgttgt tgagagatta gttactgtat gccggataga tgattacatc gcatccggca
    10441 cgatcacagg acattagatc ccatccccat actcaaatgt atggttaata ccgttgaaat
    10501 gctggtccat atccattgat ggcttatcgc tgtctggttt accgacaata cgagccggaa
    10561 cgccagcggc ggttgtatgc ggcggcaccg gttgcagcac cacggaacct gcgccaatct
    10621 tcgcgccgcg accaacttca atattgccga ggattttcgc gcccgcgcca atcatcacac
    10681 cttcacgaat tttcgggtga cggtcaccac cagatttacc cgtaccgcca agcgtcacag
    10741 attgcagaat cgatacgtcg ttttcaatta ccgccgtttc acccacaacg atgcccgtgg
    10801 cgtggtcgag cataatgcca cggccaattt ttgctgccgg gtgaatatcg acctggaacg
    10861 tcacagaaac ctggttttgc agaaagattg ccaatgcgcg acgcccctga ttccacaacc
    10921 agtgaccgat gcgataggcc tgcaaggcat gaaaaccctt caggtataac aacggggttg
    10981 agtatttatc gactgccggg tcgcgggtac gcaccgcctg aatatcacag gccgcagagg
    11041 cgatcatttc cgggtcagcg gcgtaggctt cttccaccac ttcacggata gcaatagcag
    11101 gcataattgg cgatgacagc ttgttcgcca gcatgtagct cagtgcactt ccaaggtttt
    11161 cgtgcttgag tagcgtcgcg tggtaaaaac tggccagcat tggctcacag tccgccagcg
    11221 ttctggcttc ggctttaata ttgttccaga caatttccag ttcttcacac gacattgctt
    11281 actccacacg atgagataat gaccggcccg ttctgcgcgg gccgggtcat agcggtaaca
    11341 aaggttccct ggggttagtg gctgctgcgc tcgtccttgc gtgcacgacc taataacgtc
    11401 aatgctgcct cgcgcgcgtt ttttccgcaa tataatactt gataaatttc ctcggttatt
    11461 ggcatttcaa cgccgaagcg atgcgccagt tcgcggactt ctttcgtatt gcggtagcct
    11521 tccaccacct gaccaatctt ctcctgcgcg ctttgtacat ccatgccctg accgagcatc
    11581 atgccaaaac ggcggttacg cgactggttg tcggtacagg taagcaccag atcgccaagc
    11641 cccgccatgc ccataaaggt ggcaggatcg gcacccagcg ccgcaccaag acgcgacatt
    11701 tcagccagcc cacgggtgat cagcgccgta cgcgcattcg caccaaaacc gataccgtcg
    11761 gacatccccg cgccaatggc aatgacgttt ttcaccgcac cgccaagctg cacaccgatg
    11821 aaatccgggt tgctgtaaac gcggaaactt ttgccacagt gcagcaattg ttggagatca
    11881 tcggcaaagg tctggtcggt agaggccaac gaaatagccg tcggtaaacc tgccgccagt
    11941 tctttcgcaa acgttgggcc agagataacc gccagcggaa tttgatcgcc taaggcctca
    12001 cgcgccacgt cctgtaacag acgtccggtt tccgcttcca gccctttggt cgcccacacc
    12061 agacgcgcat caggacgcat cagcggttta atctggcgca gcacttcacc aaagacatgg
    12121 ctgggtacga cgacgagaat attacggctg gctgccagcg cagtggcgag atcgctttca
    12181 agatggagcg tatcgggaaa aggcacatcg gggagaaacg cggcgttaca gcggtcgcgt
    12241 tcaagcgttg cgatatgttc agggtcatgg ccccagagga caacctcgtg gccatttctt
    12301 gccagggtga tggcaagagc ggtgccgtac gagccggcac cgatcacagt cattgaagca
    12361 ttacgttggt tcatcaggca tcctgatgtt cttcagtacc ttcgccagcc tgctgctgca
    12421 aatagttcat gaacagcgca tcgaagttaa ccggcgcaag gttcagttgc gggaatgtac
    12481 cgcgggatac catgctggtg atgcactcac gagcatacgg gaacagaatg ttcgggcagt
    12541 atgcgcccag gcaatgtgcc atctgggtgc cttcgatacc cgcgatggag aaaataccgc
    12601 cctgctgaac ttcacacagg aacgcggttt cttcgcccag ggaggccgtt acggtaacac
    12661 gcagtaccac ttcgtaaacg tcatctgcca gttgagtaga tgccgtatcc agatcaagtt
    12721 taacttctgg ctgccaatct ttctggaaaa cgtgcggcgc gttcggcgct tcgaaagaaa
    12781 tatccttggt ataaatacgt tggatctgga aagtcatttc ggtgttgttt tgttctgaca
    12841 tgtgtagaaa acccttaagt gttgtcctta aatactgcgc aatgtaatgc caacgttcac
    12901 acgttatttc agcaggggat ccagtccacc acgtgcatcc aatgcataca agtcatcaca
    12961 gccgccaatg tgctgtgcgt caataaaaat ctggggaacc gtggtgcgac cgctgcgttt
    13021 gatcatctct tcacgcttgg cggcattgcc atcgatcggc aactcctgga aactcacgcc
    13081 cttgctgctc agcagtgctt ttgcacgatg gcaatacggg caggtttctt tagtatagat
    13141 ttcaacattg gccataaatt agctcctgtt ttttaccctg aaatttcatg ttgcagggcg
    13201 gcagcaaaat ggagtgtccc cagaagctta taacaataag tcgctggggg cctaattgca
    13261 gctaacggcc tgcatcatga aagacgacag gtaaattatt tgccgcgcac caaaggcaag
    13321 ttttcgccag cccagccagc gacgccctct ttcagcacga atacttgcgc aaaaccagct
    13381 ttcgtcagcg catttgcagg ctcctggcac tgcaggccag aaccgtctac cacgataacc
    13441 ggtttgtctt tgtgcttctc aagctcacca acattgttgg ctttgatttc gctcggcaac
    13501 agattgatag aacctgcgat atggccttta cggaagtcat cacgctgacg taaatccaca
    13561 accacagcgt cttctttgtt gatcagacgc gtagcttcac cacgactaat caccttcact
    13621 ttcgaggtca ggctcttaaa cgtagtcaca agaaccgcca ccagtaacgc gatccaggcg
    13681 atactcagta tgggatgacg gccaacaaat tgcataattt cttgcatggg gggtaacaac
    13741 tcccgacgta gtgattaaaa aaaccaggaa aggagtatac ctgcgcggtg cggcaaatac
    13801 agccagcgcg ttaactggaa tgcaattttg cggggcgcga cgaaaaaaaa gcgtaaatct
    13861 ggcatcggct tgccgcgagc ggtcgtatat tttgatcttc agaggctatt ttatcgattc
    13921 agctgtagta aaattacgca aattttgact cttgagtatg aggttgtcgc aatgtcggtt
    13981 tctaaaaaac ctatggtact ggtgattctg gatggctatg gctatcgcga agaacagcag
    14041 gataacgcca tttttagtgc taaaaccccg gtaatggatg cactgtgggc caatcgtccg
    14101 cataccctga tcgacgcttc cggtctggaa gtcggtctgc ctgaccgtca gatgggtaac
    14161 tccgaagtag gccacgttaa cctgggtgcc ggccgcatcg tgtatcagga cctgactcgt
    14221 ctggacgttg aaatcaaaga tcgcgctttc tttgctaatc cagtgctgac tggcgcggta
    14281 gataaagcga aaaacgcagg taaagcagta cacattatgg gtctgctctc cgcaggcggc
    14341 gtacacagcc acgaagatca catcatggcg atggtagaac tggcagctga acgcggcgca
    14401 gaaaaaatct acctgcacgc attccttgac ggtcgcgaca ccccgccgcg cagtgctgaa
    14461 tcctcgctga aaaaatttga agagaaattt gctgcgctgg gtaaaggccg cgtagcgtcc
    14521 atcattggtc gttactacgc gatggaccgc gataaccgtt gggatcgcgt tgaaaaagcc
    14581 tatgacctgc tgactctggc gcagggtgag ttccaggccg atactgccgt tgctggtttg
    14641 caggcagctt atgctcgcga cgaaaacgac gagttcgtga aagcgaccgt tattcgtgca
    14701 gaaggtcagc cagatgcggc aatggaagac ggcgatgcgc tgattttcat gaacttccgt
    14761 gctgaccgcg cgcgtgaaat cactcgtgca ttcgtgaacg ctgatttcga tggcttcgcg
    14821 cgtaagaaag tggttaacgt cgatttcgtg atgctgaccg aatacgccgc tgacatcaaa
    14881 actgcggttg cttacccacc cgcttccctg gttaacacct tcggcgagtg gatggcgaaa
    14941 aacgacaaaa ctcagttgcg tatttccgaa accgaaaaat atgcccacgt tactttcttc
    15001 ttcaacggtg gcgtagaaga gtcgttcaaa ggcgaagatc gcattctgat caactcaccg
    15061 aaagtggcta cctacgatct gcaaccggaa atgagctccg cagagctgac cgaaaaactg
    15121 gttgcggcca tcaagagcgg caaatacgac accattatct gtaactatcc gaacggcgac
    15181 atggtaggtc acaccggggt gatggaagcg gcggttaaag cggttgaagc actggatcac
    15241 tgcgtggaag aagtcgcgaa agcggttgag tccgtgggtg gacaactgct gatcaccgct
    15301 gaccacggta acgctgaaca gatgcgcgat ccggcaacgg gtcaggcaca cacggcacac
    15361 accaacctgc cagttccgct gatttatgtt ggtgataaga acgtgaaagc ggttgaaggc
    15421 ggcaaacttt ctgacatcgc gccgaccatg ttgtcgctga tgggtatgga aatcccgcaa
    15481 gagatgactg gtaagccgct gttcatcgtg gaataatccc tccccatgag gggaaaggcg
    15541 attaatacca tgacacgggc cgtgaaaccg cgcaggtttg caatcaggcc catcatctac
    15601 gccagcgttc ttagcgctgg cgtattgttg tgcgcctttt ccgcccacgc ggatgagcgt
    15661 gaccaactca aatctattca ggccgatatc gccgcaaaag agcgcgcggt acgccaaaag
    15721 caacaacaac gcgcaagcct gctcgcacaa ttgaaaaagc aggaagaagc gatctctgaa
    15781 gccacccgta agctgcgcga aacgcaaaac acgctcaatc aactcaataa acagattgat
    15841 gagatgaacg cgtcgattgc caaactggag cagcaaaaag ccgcccagga gcgcagcctc
    15901 gccgcgcaac tggatgccgc attccgtcag ggcgagcata ccggtattca gctaattctc
    15961 agcggtgaag aaagccagcg tggacagcgt ttacaggctt atttcggcta tctcaaccag
    16021 gcgcgacaag aaaccattgc ccagttgaag caaacgcgtg aagaagtcgc catgcagcgt
    16081 gctgaactgg aagagaaaca aagcgagcaa caaacgctgt tatatgaaca gcgcgcccaa
    16141 caggcgaaac tgactcaggc tctgaacgag cgtaaaaaga cgctggcggg gctggaatct
    16201 tccatccagc aaggtcagca gcagctaagt gaactgcgtg ccaacgaatc ccgtctgcgt
    16261 aacagcattg cccgtgcgga agccgcggcg aaagcgcgtg ctgaacgaga agcgcgtgag
    16321 gcccaggcgg ttcgcgaccg ccagaaagaa gcgacgcgca aaggcaccac ctataaaccg
    16381 accgaaagcg aaaaatcgct gatgtcccga actggtggcc tgggtgcgcc gcgtggtcag
    16441 gcattctggc cggttcgcgg gccgacgctg catcgctatg gtgaacagct acagggcgaa
    16501 ctacgctgga aaggaatggt tatcggtgcc tctgaaggta ctgaagttaa agcgattgcc
    16561 gacggtcggg tgattctggc tgactggctg caaggttacg gtctggtggt ggtggttgag
    16621 cacggtaaag gcgacatgag tctttacggc tataatcaga gcgcactggt gagcgttggt
    16681 tcgcaggttc gcgcgggcca gccaattgca ctggtgggca gcagtggcgg tcagggtcgg
    16741 ccttcactct atttcgaaat tcgccgccag ggtcaggcgg tcaatccaca gccgtggttg
    16801 ggaagataag ttttgtttcc atttcgtcgt aacgttcttg catttgccgc tctgttggcg
    16861 ctctcctccc ccgtacttgc tggcaaactt gccatcgtca ttgatgattt tgggtatcgc
    16921 ccgcacaacg aaaaccaggt gctggcgatg ccctccgcta tctccgtcgc tgtattaccc
    16981 gattcaccgc acgccagaga gatggcgacc aaagcgcata acagcgggca cgaagtgttg
    17041 attcatctcc cgatggcacc actgagtaaa cagccgctgg agaaaaatac gctgcgcccg
    17101 gagatgagca gcgacgaaat tgagcgcatt attcgtagtg cggtcaataa cgtgccctat
    17161 gccgtgggga tcaacaacca catgggtagc aagatgacct ctaacctgtt tggtatgcag
    17221 aaagtgatgc aggcactgga gcgttacaat ctttacttcc tcgacagcgt aaccatcggt
    17281 aatacccagg cgatgcgcgc cgcgcaaggt actggcgtga aggtgatcaa acggaaggtg
    17341 ttcctcgacg attcgcagaa cgaagcggac atccgtgtgc aatttaatcg cgcaattgat
    17401 ctggcgcgtc gcaacggttc aaccattgcc attgggcatc ctcacccttc aacggtacgc
    17461 gtgctacaac agatggttta taacctgccg ccagacatta cgctggtgaa agccagcagc
    17521 ttgctgaatg aaccgcaggt tgatacttct acaccgccga aaaacgctgt gcctgatgca
    17581 ccgcgtaatc cgttccgtgg cgtgaagctg tgcaaaccga agaaaccgat agaacctgtt
    17641 tatgctaatc gcttctttga agtattaagc gaaagcatca gccagagcac gctgatcgtt
    17701 tacttccagc atcagtggca aggctggggc aaacagcccg aagcggcgaa gtttaacgct
    17761 agcgcaaatt aaaggcgcta cgcgtaatgc gatggtgcga ccgcgttttg tcgcgccatt
    17821 gccataagcg gaaagaccac agtaacgcct ggtaaccgac cttcacgctg cgcacattgg
    17881 taatcaggcg cttatacata ccggaagtaa atatctcggc aatcatccgt tggcgggtaa
    17941 gaatatccgg ctctttgcgc accgcatggc aaacacgcaa tgcttcgtaa gttatttgct
    18001 gatgaaattc cggataaatc gtaattttgt cggcataatt tcgatttaat ttctccagca
    18061 ggcgggtaat cttaatatag tgacgttgat aattaaggtt tttattccct tgtctatgca
    18121 accgactcac tgacgtatta tgcagataat attcatataa tgattgctcg gtatatcgcg
    18181 cacgcagcgc gttaaacatg aattctgttg tccagacaat atcctgatga tgtaatccgg
    18241 caataaattt aatgttattt ttaacaataa catcacggcg ataaaccccc atccagacaa
    18301 cgtgagtcca acggcgcgaa gaaagcccca tccgcagcca gtccgggccg gttaatacgc
    18361 cggttgagcg aaggcgatcg ctggggatgg attgccaggt ttctcccgtt tcacgaaaac
    18421 accagtcagc gttgcactgc gccacgtcga ggtcatcctc taacgccatg gtcatcagcg
    18481 tttcgtacat ggtgggatag acctcatcgt cagcatcgac aaaagcgaca tatttgcccg
    18541 tcgccacctc gatcccacga ttacgcgcta ccgatgcgcc agcattcgcc tgatgcaaca
    18601 aacgaacgtg cggatagttt tctgcgtaat gctttgctat ttcaacagaa ttatccgttg
    18661 aaccatcgtt aataataatg atttccagag cagtccaggt ttgcgtaatt aaagattcca
    18721 tacaagtgcg gaaatcatcg cccgcattat ataacggaat aataacacta agtttattgg
    18781 tgctgttcat cataaattac cgacgacctc tgaagttatc ctgacgtttt acaggctttg
    18841 tattaagaaa ctattaagcc tgtgagatat tatttttaca ggtgagagag tcacttcagg
    18901 gtagagagat aatgagagca gctatataag agatcagcgc aattacgata tctttattac
    18961 actgacagga ttttacatat ttaacggatt atcctcaggc aaaagggctg gaataccagc
    19021 ccttgttcgt gttaatccca actcagaatt actttcccgg actggcccga acgcatagcg
    19081 tcaaagccct tctggaaatc atcaatagag aaacgatggg taatgatcgg cgagagatcc
    19141 agacctgact gaatcagcgc cgccatcttg taccaggttt caaacatctc acgaccgtaa
    19201 atacctttaa tgaacaagcc tttaaagatt actttggtcc agtcgataga catatcggac
    19261 ggtggaatac ccagcatcgc aatgcgaccg ccgtggttca tggtgtcgag catggtacga
    19321 aacgctggcg gcgcaccgga catttccaga ccgacatcaa agccttcggt catgcccagt
    19381 tctgccatca catcattaag gttttcttta gcgacgttga ccgcacgggt gatacccatt
    19441 ttgcgcgcca gctcaaggcg gtattcgtta acatcggtga tcaccacatt gcgtgcacca
    19501 acgtgtttcg ccaccgccgc agccataata cctatcggac ctgcaccaga aaccagcaca
    19561 tcttcgccca ccagatcgaa cgacagcgcg gtatgcacgg cgttaccgaa gggatcaaaa
    19621 atggaagcca ggtcgtcgga gatattgtcg gggattttga aagcgttgaa cgccggaatc
    19681 accagatatt cggcgaagca gcccggacgg ttaacaccga caccaatggt gttgcggcac
    19741 agatgggtac gaccgccacg acagttgcga cagtgaccgc aggtgatatg gccttcgcca
    19801 gaaacgcgat cgccgatttt gaagcctttc acttcctgac caatacctac cacttcaccg
    19861 acatattcat ggcctacgac catcggcacc gggatggttt tttgcgacca ctcatcccag
    19921 ttatagatgt gaacgtcagt cccgcagatg gctgttttac ggattttaat cagcagatcg
    19981 ttatgcccga gttccggtac aggaacgtcg gtcatccaga tgccctcttc cgctttcagt
    20041 ttggataacg ctttcatctc acatcctcag gcgataacgc ccagttgttt accaatacgc
    20101 gtgaatgctt ctactgcacg cgtaatttgc tcaggggtat gcgccgcaga catctgggta
    20161 cgaatacgcg cctgaccttt cggaacgacc ggatagaaga aaccggtgac gtaaatgccc
    20221 tctttttgca gctcacgggc aaatttctgc gccactactg catcgccaag catgaccgga
    20281 ataatggcat gatcggctcc cgccagggta aagcccgccg ccgacatttg ctcacggaac
    20341 tggcgcgcgt tcgcccacag acggtcacgc agttcgctgc ccgcttcgac catctccagt
    20401 actttgatgg acgcggcaac aatggccggt gccagcgagt tggagaacag gtacggacga
    20461 gaacgctggc gcagccactc aaccacctct ttgcgcgccg cggtataacc accagaagcc
    20521 ccgcccagcg ctttaccaag cgtaccggtg ataatatcga cccggcccat cacatcgcag
    20581 tattcatggg aaccacgacc attttcaccg acaaaaccga ccgcgtggga gtcatccacc
    20641 atcaccaggg catcgtattt atctgccaga tcgcaaacgc ctttcaggtt ggcaatcacg
    20701 ccgtccattg agaacacacc atcggtggca atcagcacat gacgcgcacc ggcttcacgc
    20761 gcttctttca gacgtgcttc cagctcctgc atatcgttgt tggcatagcg atagcgttta
    20821 gctttgcaca gacgcacacc atcaataata gacgcgtggt tcagtgcgtc ggagataatg
    20881 gcgtcttccg cacccagcag cgtttcaaac agtccaccgt tagcatcaaa gcaggaagag
    20941 tagagaatcg catcttccat ccccaggaat gccgccagtt tttgttcaag ctctttatgg
    21001 ctgtcctgag tgccgcaaat aaaacgcacc gaagccatgc cgaaaccgtg agaatccatt
    21061 cccgcctttg ctgccgcaat cagatccgga tgattcgcca gcccgagata gttgttggca
    21121 caaaagttaa tgacgtggct tccatcagcc acagtgatat ctgcttgctg cgcagacgta
    21181 ataatgcgct cttctttaaa caacccttcc gcccgtgcgg tttccagatc gttggttaac
    21241 tgctgataaa attctccacg cattgcgatt ctccagacag ggcaaattcc agcacatatt
    21301 acccaaactt ataggtcgcg acgagatgac gcgttaacac ttctgcaaaa ttcaggataa
    21361 ataacgtcca tcaatctcac ttttggcgaa tggctgaagc caacgccgtg tagtgatatg
    21421 atagaagtat tcgtgtctga gattgtctct gactccataa ttcgaaggtt acagttatga
    21481 tcatcgttac cggcggcgcg ggctttatcg gcagcaacat cgttaaggcc ctgaatgata
    21541 aaggcatcac cgatattctg gtggtggaca acctgaaaga cggcaccaag tttgtgaacc
    21601 tggtggatct ggatatcgcg gactatatgg ataaggaaga cttcctgatc cagattatgg
    21661 ctggcgaaga gttcggcgat gtcgaagcga ttttccacga aggcgcatgc tcttccacca
    21721 ccgagtggga cggcaagtat atgatggata acaactatca atactccaag gagctgctgc
    21781 actactgcct ggagcgcgaa atcccgttcc tgtacgcttc ttccgcagcc acctacggcg
    21841 gacgcacctc cgactttatt gaatcccgcg agtacgaaaa accgttgaac gtctacggtt
    21901 actcaaaatt cctgtttgat gaatatgttc gccaaatcct gcctgaagcg aactcgcaga
    21961 ttgttggctt ccgttatttc aacgtttatg gaccgcgtga aggccataaa ggcagcatgg
    22021 cgagcgtcgc gttccatctc aacactcagc ttaacaacgg tgaatcaccg aagctgtttg
    22081 aaggtagcga gaacttcaaa cgcgacttcg tctatgtggg cgacgtggca gatgtaaacc
    22141 tgtggttcct ggaaaatggc gtttccggta tcttcaacct cggcaccggt cgtgcagaat
    22201 ccttccaggc agtagcagat gctacgctgg cttatcacaa gaaaggccag atcgaataca
    22261 ttccgttccc ggataagctg aaaggccgct accaggcgtt cactcaggca gatctgacaa
    22321 atctgcgcgc ggcgggttac gacaaaccat tcaaaaccgt tgctgaaggt gtaacggaat
    22381 acatggcctg gctgaatcgc gacgcataag agctctgcat gaaaatactg gtgatcggcc
    22441 cgtcttgggt tggcgacatg atgatgtcgc aaagtctcta tcgcacgctc caggcgcgct
    22501 atccccaggc gataatcgat gtgatggcac cggcatggtg ccgtccatta ttatcgcgga
    22561 tgccggaagt taacgaagct atccctatgc ctctcggtca cggagcgctg gaaatcggcg
    22621 aacgccgcaa actgggtcat agcctgcgtg aaaagcgcta cgaccgcgcc tacgtcttac
    22681 ccaactcctt caaatccgca ttagtgcctt tcttcgcggg tattcctcat cgcaccggct
    22741 ggcgcggcga gatgcgctac ggtttactca acgatgtacg cgtgctcgat aaagaagcct
    22801 ggccgctaat ggtggaacgc tatgtcgcgc tggcctatga caaaggcgtg atgcgtaccg
    22861 cacaagatct gccgcagcca ttgttatggc cgcagttgca ggtgagcgaa ggtgaaaaat
    22921 catatacctg taatcaattt tcgctttcat cagaacgtcc gatgattggt ttttgcccgg
    22981 gggcggagtt tggtccggca aaacgctggc cacactacca ctatgctgag ctggcaaagc
    23041 agctgattga tgaaggttat caggtggttc tgtttggctc ggcgaaagat catgaggcgg
    23101 gcaatgagat tcttgccgct ttgaataccg agcagcaggc atggtgtcgg aacctggcgg
    23161 gggaaacaca gcttgatcaa gcggttatcc tgattgcagc ctgtaaagcc attgtcacta
    23221 acgattctgg cctgatgcac gttgcggcgg cgctcaatcg tccgctggtt gccttgtatg
    23281 gtccaagtag cccggacttc acaccgccgc tatcccataa agcgcgcgtg atccgtctga
    23341 ttaccggcta tcacaaagtg cgtaaaggtg acgctgcgga gggttatcac cagagcttga
    23401 tcgacattac tccccagcgc gtactggaag aactcaacgc gctattgtta caagaggaag
    23461 tctgacggat gcgggttttg atcgttaaaa catcgtcgat gggcgatgtt ctccatacgt
    23521 tgcccgcact cactgatgcc cagcaggcaa tcccagggat taagtttgac tgggtggtgg
    23581 aagaagggtt cgcacagatt ccttcctggc acgctgccgt tgagcgagtt attcctgtgg
    23641 caatacgtcg ctggcgtaaa gcctggttct cggcccccat aaaagctgaa cgcaaagcgt
    23701 ttcgtgaagc gctacaagca gagaactatg acgcagttat cgatgctcag gggctggtaa
    23761 aaagcgcggc gctggtgacg cgtctggcgc atggcgtaaa gcatggattg gactggcaaa
    23821 ccgctcgcga accgttagcc agcctgtttt acaatcgtaa gcatcatatt gcaaaacagc
    23881 agcacgccgt agaacgcacc cgcgaactgt ttgccaaaag tctgggctat agcaaaccgc
    23941 aaacccaggg cgattatgct attgcacagc atttcctgac gaacctgcct acagatgctg
    24001 gcgaatatgc cgtatttctt catgcgacga cccgtgatga taaacactgg ccggaagaac
    24061 actggcgaga attgattggt ttactggctg attcaggaat acggattaaa cttccgtggg
    24121 gcgcgccgca tgaggaagaa cgggcgaaac gactggcgga aggatttgct tatgttgaag
    24181 tattgccgaa gatgagtctg gaaggcgttg cccgcgtgct ggccggggct aaatttgtag
    24241 tgtcagtgga tacggggtta agccatttaa cagcggcact ggatagaccc aatatcacgg
    24301 tttatggacc taccgatccg ggattaattg gtgggtatgg gaagaatcag atggtttgta
    24361 gggctccggg gaatgagttg tctcaattga cagcaaatgc tgttaagcgg ttcattg
//
LOCUS       DAPGUL010000065        24317 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.065, whole genome shotgun sequence.
ACCESSION   DAPGUL010000065 DAPGUL010000000
VERSION     DAPGUL010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24317
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.065"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(51..347)
                     /locus_tag="RHX21_002814"
     CDS             complement(51..347)
                     /locus_tag="RHX21_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2502 domain-containing protein"
                     /protein_id="HDV1987973.1"
                     /translation="MKKMQSIVLALSLVLVAPMAAQAAEITLVPSVKLQIGDRDNRGY
                     YWDGGHWRDHGWWKQHYEWRGNRWHPHGPPPPPRHHKKAHHDHHGGHGPGKHHR"
     gene            complement(561..1847)
                     /gene="thrC"
                     /locus_tag="RHX21_002815"
     CDS             complement(561..1847)
                     /gene="thrC"
                     /locus_tag="RHX21_002815"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HDV1987974.1"
                     /translation="MKLYNLKDHNEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEID
                     EMLKLDFVTRSAKILSAFIGDEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGP
                     TLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRG
                     KISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISR
                     LLAQICYYFEAVAQLPQEARNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVN
                     DTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDE
                     TTQQTMRELKELGYTSEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESVESILGE
                     TLDLPKELAERADLPLLSHNLPADFAALRKLMMNHQ"
     gene            complement(1848..2780)
                     /gene="thrB"
                     /locus_tag="RHX21_002816"
     CDS             complement(1848..2780)
                     /gene="thrB"
                     /locus_tag="RHX21_002816"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HDV1987975.1"
                     /translation="MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVEAAETF
                     SLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACS
                     VVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDI
                     ISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQ
                     PELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPDTA
                     QRVADWLGKNYLQNQEGFVHICRLDTAGARVLEN"
     gene            complement(2782..5244)
                     /gene="thrA"
                     /locus_tag="RHX21_002817"
     CDS             complement(2782..5244)
                     /gene="thrA"
                     /locus_tag="RHX21_002817"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase I"
                     /protein_id="HDV1987976.1"
                     /translation="MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKIT
                     NHLVAMIEKTISGQDALPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIK
                     HVLHGISLLGQCPDSINAALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHY
                     LESTVDIAESTRRIAASRIPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACL
                     RADCCEIWTDVDGVYTCDPRQVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQF
                     QIPCLIKNTGNPQAPGTLIGASRDEDELPVKGISNLNNMAMFSVSGPGMKGMVGMAAR
                     VFAAMSRARISVVLITQSSSEYSISFCVPQSDCVRAERAMQEEFYLELKEGLLEPLAV
                     TERLAIISVVGDGMRTLRGISAKFFAALARANINIVAIAQGSSERSISVVVNNDDATT
                     GVRVTHQMLFNTDQVIEVFVIGVGGVGGALLEQLKRQQSWLKNKHIDLRVCGVANSKA
                     LLTNVHGLNLENWQEELAQAKEPFNLGRLIRLVKEYHLLNPVIVDCTSSQAVADQYAD
                     FLREGFHVVTPNKKANTSSMDYYHLLRHAAEKSRRKFLYDTNVGAGLPVIENLQNLLN
                     AGDELMKFSGILSGSLSYIFGKLDEGMSFSEATTLAREMGYTEPDPRDDLSGMDVARK
                     LLILARETGRELELADIEIEPVLPAEFNAEGDVAAFMANLSQLDDLFAARVAKARDEG
                     KVLRYVGNIDEDGACRVKIAEVDGNDPLFKVKNGENALAFYSHYYQPLPLVLRGYGAG
                     NDVTAAGVFADLLRTLSWKLGV"
     misc_feature    complement(5270..5389)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00506"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Thr leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00506"
     gene            complement(5325..5390)
                     /gene="thrL"
                     /locus_tag="RHX21_002818"
     CDS             complement(5325..5390)
                     /gene="thrL"
                     /locus_tag="RHX21_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thr operon leader peptide"
                     /protein_id="HDV1987977.1"
                     /translation="MKRISTTITTTITITTGNGAG"
     gene            complement(5604..6290)
                     /locus_tag="RHX21_002819"
     CDS             complement(5604..6290)
                     /locus_tag="RHX21_002819"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA/rRNA methyltransferase"
                     /protein_id="HDV1987978.1"
                     /translation="MRITIILVAPARAENIGAAARAMKTMGFSELRIVDSQAHLEPAT
                     RWVAHGSGDIIDNIKVFPTLAESLHDVDFTVATTARSRAKYHYYATPVELVPLLEEKS
                     SWMSHAALVFGREDSGLTNEELALADVLTGVPMVADYPSLNLGQAVMVYCYQLATLIQ
                     QPAKSDTTADQHQLQALRERVMALLTTLAVADDIKLVDWLQQRLGLLEQRDTAMLHRL
                     LHDIEKNITK"
     gene            complement(6690..6830)
                     /locus_tag="RHX21_002820"
     CDS             complement(6690..6830)
                     /locus_tag="RHX21_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987979.1"
                     /translation="MTKVRNCVLDALSINVNNIISLVVGTFPQDPTVSKTAVILTILT
                     AT"
     gene            6926..7642
                     /gene="arcA"
                     /locus_tag="RHX21_002821"
     CDS             6926..7642
                     /gene="arcA"
                     /locus_tag="RHX21_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003621071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator ArcA"
                     /protein_id="HDV1987980.1"
                     /translation="MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILS
                     EYDINLVIMDINLPGKNGLLLARELREQANVALMFLTGRDNEVDKILGLEIGADDYIT
                     KPFNPRELTIRARNLLSRTMNLGTVSEERRSVESYKFNGWELDINSRSLIGPDGEQYK
                     LPRSEFRAMLHFCENPGKIQSRAELLKKMTGRELKPHDRTVDVTIRRIRKHFESTPDT
                     PEIIATIHGEGYRFCGDLED"
     gene            complement(7702..9054)
                     /gene="creD"
                     /locus_tag="RHX21_002822"
     CDS             complement(7702..9054)
                     /gene="creD"
                     /locus_tag="RHX21_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein CreD"
                     /protein_id="HDV1987981.1"
                     /translation="MLKSPLFWKMTTLFGAVLLLLIPIMLIRQVIVERADYRSDVEDA
                     IRQSTSGPQKLVGPLIAIPVTELYTVQEDDKTVERKRSFIHFWLPESLMVDGNQNVEE
                     RKIGIYTGQVWHSDLTLKADFDVSRLSELDAPNITLGKPFIVISVGDARGIGVVKAPE
                     VNGTALTIEPGTGLEQGGQGVHIPLPEGDWRKQNLKLNMALNLSGTGDLSVVPAGRNS
                     EMTLTSNWPHPSFLGDFLPAKREVSESGFQAQWQSSWFANNLGERFASGNDTGWENFP
                     AFSVAVTTPADQYQLTDRATKYAILLIALTFMAFFVFETLTAQRLHPMQYLLVGLSLV
                     MFYLLLLALSEHTGFTVAWIIASLIGALMNGIYLQAVLKGWRNSMLFTLALLLLDGVM
                     WGLLNSADSALLLGTSVLVVALAGMMFVTRNIDWYAFSLPKMKASKEVTMDDQLRIWK
                     "
     gene            complement(9112..10536)
                     /gene="creC"
                     /locus_tag="RHX21_002823"
     CDS             complement(9112..10536)
                     /gene="creC"
                     /locus_tag="RHX21_002823"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CreC"
                     /protein_id="HDV1987982.1"
                     /translation="MRIGMRLLLGYFLLVAVAAWFVLAIFVKEVKPGVRRATEGTLID
                     TATLLAELARPDLLSGDPTHGQLAQAFNQLQHRPFRANIGGINKVRNEYHVYMTDSQG
                     KVLFDSANKAVGQDYSRWNDVWLTLRGQYGARSTLQNPADPESSVMYVAAPIMDGSRL
                     IGVLSVGKPNAAMAPVIKRSERRILWASAILLGIALVIGAGMVWWINRSIARLTRYAD
                     SVTDNKPVPLPDLGSSELRKLAQALESMRVKLEGKNYIEQYVYALTHELKSPLAAIRG
                     AAEILREGPPPEVVARFTDNILTQNARMQALVETLLRQARLENRQEVVLTAVDVAALF
                     RRVSEARTVQLAEKNITLHVTPTEVNVAAEPALLDQALGNLLDNAIDFTPESGRITLS
                     AEVDQEHVTLKVLDTGSGIPDYALSRIFERFYSLPRANGQKSSGLGLAFVSEVARLFN
                     GEVTLRNVQEGGVLASLRLHRHFT"
     gene            complement(10536..11225)
                     /gene="creB"
                     /locus_tag="RHX21_002824"
     CDS             complement(10536..11225)
                     /gene="creB"
                     /locus_tag="RHX21_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CreB"
                     /protein_id="HDV1987983.1"
                     /translation="MQRETVWLVEDEQGIADTLVYMLQQEGFAVEVFERGLPVLDKAR
                     QLVPDVMILDVGLPDISGFELCRQLLALHPALPVLFLTARSEEVDRLLGLEIGADDYV
                     AKPFSPREVCARVRTLLRRVKKFSSPSPVIRIGHFELNEPAAQISWFDTPLTLTRYEF
                     LLLKTLLKSPGRVWSRQQLMDSVWEDAQDTYDRTVDTHIKTLRAKLRAINPDLSPINT
                     HRGMGYSLRGL"
     gene            complement(11238..11711)
                     /gene="creA"
                     /locus_tag="RHX21_002825"
     CDS             complement(11238..11711)
                     /gene="creA"
                     /locus_tag="RHX21_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein CreA"
                     /protein_id="HDV1987984.1"
                     /translation="MKYKHLILSLSLIMLGPLAHAEEIGSVDTVFKMIGPDHKIVVEA
                     FDDPDVKNVTCYVSRAKTGGIKGGLGLAEDTSDAAISCQQVGPIELSDRIKNGKAQGE
                     VVFKKRTSLVFKSLQVVRFYDAKRNALAYLAYSDKVVEGSPKNAISAVPVMPWRQ"
     gene            11922..12791
                     /gene="robA"
                     /locus_tag="RHX21_002826"
     CDS             11922..12791
                     /gene="robA"
                     /locus_tag="RHX21_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MDR efflux pump AcrAB transcriptional activator
                     RobA"
                     /protein_id="HDV1987985.1"
                     /translation="MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKD
                     VTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQQTFTRAFKKQFAQTPAL
                     YRRSPEWSAFGIRPPLRLGEFTMPEHKFVTLEDTPLIGVTQSYSCSLEQISDFRHEMR
                     YQFWHDFLGNAPTIPPVLYGLNETRPSQDKDDEQEVFYTTALAQDQADGYVLTGHPVM
                     LQGGEYVMFTYEGLGTGVQEFILTVYGTCMPMLNLTRRKGQDIERYYPAEDAKAGDRP
                     INLRCELLIPIRR"
     gene            complement(12788..13435)
                     /gene="gpmB"
                     /locus_tag="RHX21_002827"
     CDS             complement(12788..13435)
                     /gene="gpmB"
                     /locus_tag="RHX21_002827"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase GpmB"
                     /protein_id="HDV1987986.1"
                     /translation="MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAK
                     ELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRLRELNMGVLEKRHIDSLTEEEEN
                     WRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVST
                     ILGLPAWAERRLRLRNCSISRVDYQESLWLASGWVVETAGDISHLDAPALDELQR"
     gene            13487..13999
                     /gene="yjjX"
                     /locus_tag="RHX21_002828"
     CDS             13487..13999
                     /gene="yjjX"
                     /locus_tag="RHX21_002828"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418811.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inosine/xanthosine triphosphatase"
                     /protein_id="HDV1987987.1"
                     /translation="MHQVVCATTNPAKIQAILQAFHEIFGEGSCHIASVAVESGVPEQ
                     PFGSEETRAGARNRVANARRLLPEADFWVAIEAGIDGDSTFSWVVIENASQRGEARSA
                     TLPLPAVILQKVREGEALGPVMSRYTGIDEIGRKEGAIGVFTAGKLTRASVYHQAVIL
                     ALSPFHNAVY"
     gene            complement(14041..14367)
                     /gene="trpR"
                     /locus_tag="RHX21_002829"
     CDS             complement(14041..14367)
                     /gene="trpR"
                     /locus_tag="RHX21_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trp operon repressor"
                     /protein_id="HDV1987988.1"
                     /translation="MAQQSPYSAAMAEQRHQEWLRFVDLLKNAYQNDLHLPLLNLMLT
                     PDEREALGTRVRIVEELLRGEMSQRELKNELGAGIATITRGSNSLKAAPVELRQWLEE
                     VLLKSD"
     gene            complement(14457..16394)
                     /gene="sltY"
                     /locus_tag="RHX21_002830"
     CDS             complement(14457..16394)
                     /gene="sltY"
                     /locus_tag="RHX21_002830"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418809.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase"
                     /protein_id="HDV1987989.1"
                     /translation="MEKAKQVTWRLLAAGVCLLTVSSVARADSLDEQRSRYAQIKQAW
                     DNRQMDVVEQMMPGLKDYPLYPYLEYRQITDDLMNQPAVTVTNFVRANPTLPPARTLQ
                     SRFVNELARREDWRGLLAFSPEKPGTTEAQCNYYYAKWNTGQSEEAWQGAKELWLTGK
                     SQPNACDKLFSVWRASGKQDPLAYLERIRLAMKAGNTGLVTVLAGQMPADYQTIASAI
                     ISLANNPNTVLTFARTTGATDFTRQMAAVAFASVARQDAENARLMIPSLAQAQQLNED
                     QIQELRDIVAWRLMGNDVTDEQAKWRDDAIMRSQSTSLIERRVRMALGTGDRRGLNTW
                     LARLPMEAKEKDEWRYWQADLLLERGREAEAKEILHQLMQQRGFYPMVAAQRIGEEYE
                     LKIDKAPQNVDSALTQGPEMARVRELMYWNLDNTARSEWANLVKSKSKTEQAQLARYA
                     FNNQWWDLSVQATIAGKLWDHLEERFPLAYNDLFKRYTSGKEIPQSYAMAIARQESAW
                     NPKVKSPVGASGLMQIMPGTATHTVKMFSIPGYSSPGQLLDPETNINIGTSYLQYVYQ
                     QFGNNRIFSSAAYNAGPGRVRTWLGNSAGRIDAVAFVESIPFSETRGYVKNVLAYDAY
                     YRYFMGDKPTLMSATEWGRRY"
     gene            16605..18272
                     /gene="ettA"
                     /locus_tag="RHX21_002831"
     CDS             16605..18272
                     /gene="ettA"
                     /locus_tag="RHX21_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017145039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-dependent translational throttle protein
                     EttA"
                     /protein_id="HDV1987990.1"
                     /translation="MAQFVYTMHRVGKVVPPKRHILKNISLSFFPGAKIGVLGLNGAG
                     KSTLLRIMAGIDKDIEGEARPQPDIKIGYLPQEPQLNPEHTVRESIEEAVSEVVNALK
                     RLDEVYALYADPDADFDKLAAEQGRLEEIIQAHDGHNLNVQLERAADALRLPDWDAKI
                     ANLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWLERFLHDFEGTVVAITHD
                     RYFLDNVAGWILELDRGEGIPWEGNYSSWLEQKDQRLAQEASQEAARRKSIEKELEWV
                     RQGTKGRQSKGKARLARFEELNSTEYQKRNETNELFIPPGPRLGDKVLEVSNLRKSYG
                     DRLLIDDLSFSIPKGAIVGIIGPNGAGKSTLFRMISGQEQPDSGTITLGETVKLASVD
                     QFRDSMDNSKTVWEEVSGGLDIMKIGNTEMPSRAYVGRFNFKGVDQGKRVGELSGGER
                     GRLHLAKLLQVGGNMLLLDEPTNDLDIETLRALENALLEFPGCAMVISHDRWFLDRIA
                     THILDYQDEGKVEFFEGNFTEYEEYKKRTLGADALEPKRIKYKRIAK"
     gene            complement(18579..19811)
                     /gene="nadR"
                     /locus_tag="RHX21_002832"
     CDS             complement(18579..19811)
                     /gene="nadR"
                     /locus_tag="RHX21_002832"
                     /EC_number="2.7.1.22"
                     /EC_number="2.7.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418807.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional transcriptional
                     regulator/nicotinamide-nucleotide
                     adenylyltransferase/ribosylnicotinamide kinase NadR"
                     /protein_id="HDV1987991.1"
                     /translation="MSSFDYLKTAIKQQGCTLQQVADASGMTKGYLSQLLNAKIKSPS
                     AQKLEALHRFLGLEFPRQKKTIGVVFGKFYPLHTGHIYLIQRACSQVDELHIIMGFDD
                     TRDRALFEDSAMSQQPTVPDRLRWLLQTFKYQKNIRIHAFNEEGMEPYPHGWDVWSNG
                     IKKFMAEKGIQPDLIYTSEEADAPQYMEHLVIDTVLVDPKRTFMSISGAQIRENPFRY
                     WEYIPTEVKPFFVRTVAILGGESSGKSTLVNKLANIFNTTSAWEYGRDYVFSHLGGDE
                     IALQYSDYDKIALGHAQYIDFAVKYANKVAFIDTDFVTTQAFCKKYEGREHPFVQALI
                     DEYRFDLVILLENNTPWVADGLRSLGSSVDRKEFQNLLVEMLEENNIEFVRVEEDDYD
                     SRFLRCVELVREMMGEQR"
     gene            complement(19832..21214)
                     /gene="radA"
                     /locus_tag="RHX21_002833"
     CDS             complement(19832..21214)
                     /gene="radA"
                     /locus_tag="RHX21_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001399683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HDV1987992.1"
                     /translation="MAKAPKRAFVCNECGADYPRWQGQCSACHAWNTITEVRLAASPT
                     VARNERLSGYAGSAGVAKVQKLSDISLEELPRFSTGFKEFDRVLGGGVVPGSAILIGG
                     NPGAGKSTLLLQTLCKLAQQMKTLYVTGEESLQQVAMRAHRLGLPTDNLNMLSETSIE
                     QICLIAEEEQPKLMVIDSIQVMHMADVQSSPGSVAQVRETAAYLTRFAKTRGVAIVMV
                     GHVTKDGSLAGPKVLEHCIDCSVLLDGDADSRFRTLRSHKNRFGAVNELGVFAMTEQG
                     LREVSNPSAIFLSRGDEVTSGSSVMVVWEGTRPLLVEIQALVDHSMMANPRRVAVGLE
                     QNRLAILLAVLHRHGGLQMADQDVFVNVVGGVKVTETSADLALLLAMVSSLRDRPLPQ
                     DLVVFGEVGLAGEIRPVPSGQERISEAAKHGFRRAIVPAANVPKKAPEGMQIFGVKKL
                     SDALSVFDDL"
     gene            complement(21263..22231)
                     /gene="serB"
                     /locus_tag="RHX21_002834"
     CDS             complement(21263..22231)
                     /gene="serB"
                     /locus_tag="RHX21_002834"
                     /EC_number="3.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase"
                     /protein_id="HDV1987993.1"
                     /translation="MPNITWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYG
                     RGLDKQRLTQYQSKLGAAMVIVAAWCVEDYQVIRLAGSLTARATRLAHEAQLDVAPLG
                     KIPHLRTPGLLVMDMDSTAIQIECIDEIAKLAGTGEMVAEVTERAMRGELDFTASLRS
                     RVATLKGADANILQQVRENLPLMPGLTQLVLKLETLGWKVAIASGGFTFFAEYLRDKL
                     RLTAVVANELEIMDGKFTGNVIGDIVDAQYKAKTLTRLAQEYEIPLAQTVAIGDGAND
                     LPMIKAAGLGIAYHAKPKVNEKAEVTIRHADLMGVFCILSGSLNQK"
     gene            22337..22981
                     /locus_tag="RHX21_002835"
     CDS             22337..22981
                     /locus_tag="RHX21_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtjB family periplasmic protein"
                     /protein_id="HDV1987994.1"
                     /translation="MARTKLKFRLHRAVIVLFCLALLVALMQGASWFSQNHQRQRNPQ
                     LEELARTLARQVTLNVAPLMRTDSPDEKRIQAILDQLTDESRILDAGVYDEQGDLIAR
                     SGESVEVRDRLALDGKKAGGYFNQQIVEPIAGKNGPLGYLRLTLDTHTLATEAQQVDN
                     TTNILRLMLLLSLAIGVVLTRTLLQGKRTRWQQSPFLLTASKPVPEEEESEKKE"
     gene            23009..24025
                     /gene="lplA"
                     /locus_tag="RHX21_002836"
     CDS             23009..24025
                     /gene="lplA"
                     /locus_tag="RHX21_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase LplA"
                     /protein_id="HDV1987995.1"
                     /translation="MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTV
                     VIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTIST
                     SIVLNALNALGVSAEASGRNDLVVKTAEGDRKVSGSAYRETKDRGFHHGTLLLNADLS
                     RLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEAITKAFFAHYGERVEA
                     EIISPDKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFSWGGVELHFDVEKGHI
                     TRAQVFTDSLNPAPLEALAGRLQGGLYRADMLQQECEALLVDFPDQEKELRELSTWIA
                     GAVR"
     gene            24057..24206
                     /locus_tag="RHX21_002837"
     CDS             24057..24206
                     /locus_tag="RHX21_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1987996.1"
                     /translation="MIDLENQEREIINIMLSQRISWLAAVRIRHKLSLAEVSKMLGIS
                     INSLK"
BASE COUNT         5815 a         6735 c         6057 g         5710 t
ORIGIN      
        1 cagcgtcaca tcaggcgctg aatgccggat tgttacccgg catttgtcat ttagcggtga
       61 tgtttgcctg gaccatgacc gccgtgatga tcatgatgag ctttcttatg gtggcgcggc
      121 ggtggcggcg gtccgtgtgg gtgccagcga ttgcctcgcc attcataatg ttgtttccac
      181 cagccgtggt cgcgccagtg accgccatcc cagtaataac cgcgattatc acgatcgcct
      241 atctgtaatt ttactgacgg gactaacgta atttccgcag cctgcgctgc catgggagcg
      301 accagaacca gggaaagtgc gagtacgata gattgcatct ttttcacagg ttactccttt
      361 tatcattgcc cgttatgggt cgatatccgg agattacgcg atgagaacgg cggttgttat
      421 tctccgcaat cctaatctct aagttaccgc atttattgag aatttctcct ttttccctgt
      481 cgtttttctc cataatttct tcataaaaaa gccgggctgc ataaaagcaa acccggcctg
      541 attgagataa tgaatagatt ttactgatga ttcatcatca atttacgcaa cgcagcaaaa
      601 tcggcgggca gattatgtga aagcaagggt aaatcagcac gttctgccag ctcttttggc
      661 agatccaacg tttcaccgag aatcgattcc acgctctctt taaatttcgc cggatgcgcg
      721 gtgccgagga acaagccata ttcgcctgga ttcaactggt cacgcagcgc acgatacgct
      781 acggcagcgt gcggctccga ggtgtagccc agttctttta actcacgcat tgtctgttgc
      841 gtggtttcat catccacggc tgcataaccc agctctttca gttgccagat tttgcggcgg
      901 aacaactctt ccacacgcgg ccagttgttc ggctgactca cgtccatcgc gttggataac
      961 gtcgcctgag tcgctttggg tgaccactga ccgtcgtgca ggaaacgtgg cacggtatcg
     1021 ttcacgttgg tcgcagcaat aaaacgtttc accggcagac cgagtgactt cgccagcaga
     1081 cccgccgtca aatcgccgaa gtttccgctt ggcaccgaga caaccagctg gttgcgcgct
     1141 tcctgtggca gctgcgcaac agcttcaaag tagtagcaaa tctgcgccag caaacggctg
     1201 atgttaatcg agttagctga gtttaacccc agcgccactt tcagttcttc atcatcaaac
     1261 gcctgcttca ccagcgcctg acaggcatcg aaatcgccgt cgatggcaac agtttcgata
     1321 ttgccgccca acgtacagaa cagtttttct tgcagtggac tgattttgcc tcgtggatag
     1381 aggataacca ctttcacatt cggtaaaccg tagaaagcat gagccactgc cgctccggta
     1441 tcaccggagg tcgcggtcag aatggtcact ggcttatcgc ccgcaatatg ggtcagcatt
     1501 tgtgccataa agcgaccgcc gaaatcttta aatgccagcg ttggcccgtg gaacaattcc
     1561 agacaaccga catcgctttc aacattggcg accggagccg ggaaggcaaa cgccgcgcgc
     1621 acgcgctctt ccaggatttc ctgcgggatt tcatcaccaa taaacgccga gaggatcttc
     1681 gcactgcggg tgacaaaatc cagcttcagc atctcatcaa tttcagtcag gctgaattcc
     1741 ggcaggtcat gcggaaaaaa cagcccctga tttttgccca acccctgggt tacggcttgc
     1801 gcaaagctga cctgctcgtt gtgatctttc agattgtaga gtttcattta gttttccagt
     1861 actcgtgcgc ccgccgtatc cagccggcaa atatgaacaa aaccttcctg attttgcagg
     1921 tagttcttac ccaaccagtc ggcaacgcgc tgggcggtat ccggcttgtc acatagagcg
     1981 aacaaggtcg ggccggagcc ggagataccg ctcgctaccg cgccgatttc cgcgaccgcc
     2041 tgccgcgcct gccggaagcc aggcagtaac cgttcacggt agggttcagc gataacatct
     2101 ttcatcagct tcgcggcaag ctcaggctga cgggaatagc aggcgtgaat gaagccagcc
     2161 agatgtcgcc cgtgcgcaat gcaatcctgg cggcgatact gcgccggtaa aatagccctg
     2221 gcttctgccg tcgagacttt aatccccgga tacgccagca cccacagcca ctcatcaaac
     2281 cctggcactt gctggctgat gatgtcgttt tcttcgatca tcaactgcat accaccaaga
     2341 aaacacggtg ccacgttgtc gtaatgaatg ctgccggaga ttcgtccttc cagctcgccc
     2401 atcaaagcca gcaaacgagt gtcattaagc ggcttgccac agtgttcatt catcgccatc
     2461 agcgccgcga ccaccgaaca ggcgctggag cctaagcccg aaccgattgg catattcttt
     2521 tccagagtca tcgccactgg aatttgcttg ccaagctcct ggcaaaaacg ctcccagcac
     2581 tgataaacga tattttcccg tggttctgac ggcagcttat cggcaaagcg tccgaggttg
     2641 ttgagactga atgtctctgc cgcctcaacc gtgactacat ctccgagcaa tgcaccatca
     2701 acaggtgtca ccgccgcccc gagcacatca aacccgacgc tcatattggc actggaagcc
     2761 ggggcataaa ctttaaccat gtcagactcc taacttccat gagagggtac gtagcagatc
     2821 ggcaaagaca ccggcagctg taacgtcatt gcccgcacca tatccgcgca gcaccaacgg
     2881 cagcggctga taatagtggc tataaaaggc cagggcgttt tcgccatttt tcactttgaa
     2941 cagcggatca ttaccatcca cttcggcaat cttcacgcgg caggcaccat cttcatcaat
     3001 attgccaaca tagcgcaaaa cttttccttc atcacgggcc ttcgccacgc gcgcggcaaa
     3061 gagatcgtcg agctgtgaca gattcgccat aaaagcggca acatcaccct cagcgttaaa
     3121 ctctgcgggc agcacaggtt caatttcaat atccgccagc tccagttcac gtcccgtttc
     3181 acgagcgaga atcaatagct tacgcgctac atccatacca gaaagatcat ctcgcggatc
     3241 cggttcggta taacccattt cccgcgccag agtagtcgcc tcggagaaac tcatgccttc
     3301 gtctaacttg ccgaagatat aagaaagcga acctgaaaga atgccggaga acttcatcaa
     3361 ttcatcacca gcattgagca gattttgcag gttctcaata accggtaatc cagccccaac
     3421 gttggtgtca tagaggaatt tacgccgcga tttttccgcc gcatgacgca acagatggta
     3481 gtaatccatc gacgaggtgt tggccttttt gttcggcgtg acaacgtgga aaccttcgcg
     3541 caagaagtcg gcatattgat ccgccactgc ctggctggag gtgcagtcaa caatgaccgg
     3601 gttcagcaga tgatattctt tcacgaggcg aattaagcgc ccgagattaa acggctcttt
     3661 ggcttgcgcc agttcttcct gccagttttc cagatttagg ccatgcacat tggtgagcag
     3721 tgccttcgag ttggcaacac cgcagacacg taagtcgata tgtttattct tcagccagct
     3781 ttgttgacgc ttcagttgct ccagcagcgc accgccaacg ccaccgacgc caatcacaaa
     3841 cacttcgata acctgatcgg tattgaacag catctgatga gtaacgcgca cgccagtggt
     3901 cgcatcatcg ttatttacca cgacagagat tgagcgttca gaagatccct gagcaatggc
     3961 gacaatgttg atattggcgc gggccagcgc ggcaaagaat ttcgccgaga tcccacgcaa
     4021 ggtgcgcata ccatcaccta ccaccgagat aatggccagc cgttccgtca ccgccagcgg
     4081 ctccagtaag ccttctttca gttccaggta gaactcttcc tgcattgccc gttcagcccg
     4141 cacacagtcg ctttgcggaa cgcagaaact gatactgtat tcggaagatg attgcgtaat
     4201 cagcaccacg gaaatacggg cgcgtgacat cgcggcaaag acgcgcgccg ccatgccgac
     4261 cattcctttc atccccgggc cggaaacgct gaacattgcc atgttattca gattggaaat
     4321 gcccttgacc ggtaattcgt cttcatcacg actggcacca atgagcgtac ctggtgcttg
     4381 aggatttccg gtatttttaa tcaggcaagg gatctggaac tgggcgatgg gggtaatggt
     4441 gcgggggtga agaactttag cgccgaagta ggaaagctcc atcgcttcct ggtaggacat
     4501 cgacttcaac aacctcgcat cgggcacctg acgcgggtcg caggtataga ccccgtcaac
     4561 gtccgtccaa atctcgcaac aatcggcgcg taaacaggca gccagcaccg ccgcggagta
     4621 gtcggaaccg ttgcgtccaa gtaccaccag ttcgcctttt tcattaccgg cggtgaaacc
     4681 tgccatcaac accatgtgat cagccggaat gcggcttgcc gcaatacggc gggtggactc
     4741 agcaatatcg acggtagatt cgaggtaatg ccccactgcc agcagttttt cgaccggatc
     4801 gataacggta acgttgtgac cacgcgcttc taacacgccg gccataatgg cgatcgacat
     4861 tttctcgcca cggcaaatca gcgcagcgtt gatgctatcc gggcactgcc ccaacaaact
     4921 aatgccatgc aggacatgtt ttatttgggc aaattcctga tcgacgaaag ttttcaattg
     4981 cgccagcggg aaccccggct gggcggcggc gagtcccgtc aaaagttcgg caaaaatacg
     5041 ttcggcatcg ctgatattgg gtaaagcatc ctggccgcta atggtttttt caatcatcgc
     5101 caccaggtgg ttggtgattt tggcgggggc agagaggacg gtggccacct gcccctgcct
     5161 ggcattgctt tccagaatat cggcaacacg cagaaaacgt tctgcatttg ccactgatgt
     5221 accgccgaac ttcaacactc gcatggttgt tacctcgtta cctttggtcg aaaaaaaagc
     5281 ccgcactgtc aggtgcgggc ttttttctgt gtttcctgta cgcgtcagcc cgcaccgtta
     5341 cctgtggtaa tggtgatggt ggtggtaatg gtggtgctaa tgcgtttcat ggatgttgtg
     5401 tactctgtaa tttttatctg tctgtgcgct atgcctatat tggttaaagt atttagtgac
     5461 ctaagtcaat aaaattttaa tttactcacg gcaggtaacc agttcagaag ctgctatcag
     5521 acactctttt tttaatccac acagagacat attgcccgtt gcagtcagaa tgaaaagctg
     5581 aaaaatactt actaaggcgt tttttatttg gtgatatttt tttcaatatc atgcagcaaa
     5641 cggtgcaaca ttgccgtgtc tcgttgctct aaaagcccca ggcgttgttg taaccagtcg
     5701 accagtttta tgtcatctgc cactgccaga gtcgtcagca atgccatgac tcgttcgcgt
     5761 aaagcttgca gttgatgttg gtctgccgtt gtgtcacttt tcgccggttg ttgtattaat
     5821 gttgctaatt gatagcaata gaccatcacc gcctgcccca gattgagcga aggataatcc
     5881 gccaccatcg gcacaccagt aagaacgtca gccaacgcta actcttcgtt agtcagcccg
     5941 gaatcttcgc gaccaaacac cagcgcggca tggctcatcc atgaagattt ttcctctaac
     6001 agcggcacca gttctactgg cgtggcgtag taatgatatt tcgcccgact gcgcgcagtg
     6061 gtggcgacag tgaaatcgac atcgtgtaac gattcagcca gcgtcgggaa aactttaata
     6121 ttatcaataa tatcaccaga tccatgtgcg acccagcggg tggctggctc caggtgcgct
     6181 tgactatcga caatccgcag ttcgctaaaa cccatcgttt tcattgcccg cgccgctgcc
     6241 ccaatatttt ctgctctggc gggtgcgacc agaataatcg ttatacgcat attgccactc
     6301 ttcttgacca aataaccgcg aacagggtga tcactgtcaa cttattacgc ggtgcgaatt
     6361 tacaaattct taacgtaagt cgcagaaaaa gccctttact tagcttaaaa aaggctaaac
     6421 tatttcctga ctgtactaac ggttgaattg ttaaaaaatg ctacatatcc ttctgtttac
     6481 ttaggataat tttataaaaa ataaatctcg acaattggat tcaccacgtt tattagttgt
     6541 atgatgcaac tagttggatt attaaaataa tgtgacgaaa gctagcattt agatacgatg
     6601 atttcatcaa actgttaacg tgctacaatt gaacttgata tatgtcaacg aagcgtagtt
     6661 ttattgggtg tccggcccct cttagcctgt tatgttgctg ttaaaatggt taggatgaca
     6721 gccgtttttg acactgtcgg gtcctgaggg aaagtaccca cgaccaagct aatgatgttg
     6781 ttgacgttga tggaaagtgc atcaagaacg caattacgta ctttagtcat gttacgccga
     6841 tcatgttaat ttgcagcatg catcaggcag gtcagggact tttgtacttc ctgtttcgat
     6901 ttagttggca atttaggtag caaacatgca gaccccgcac attcttatcg ttgaagacga
     6961 gttggtaaca cgcaacacgt tgaaaagtat tttcgaagcg gaaggctatg atgttttcga
     7021 agcgacagat ggcgcggaaa tgcatcagat cctctctgaa tatgacatca acctggtgat
     7081 catggatatc aatctgccgg gtaagaacgg tcttctgtta gcgcgtgaac tgcgcgagca
     7141 ggcgaatgtt gcgttgatgt tcctgactgg ccgtgacaac gaagtcgata aaattctcgg
     7201 cctcgaaatc ggtgcagatg actacatcac caaaccgttc aacccgcgtg aactgacgat
     7261 tcgtgcacgc aacctgctgt cccgtaccat gaatctgggt actgtcagcg aagaacgtcg
     7321 tagcgttgaa agctacaagt tcaatggttg ggaactggac atcaacagcc gttcgttgat
     7381 cggccctgat ggcgagcagt acaagctgcc gcgcagcgag ttccgcgcca tgcttcactt
     7441 ctgtgaaaac ccaggcaaaa ttcagtctcg tgctgaactg ctgaagaaaa tgaccggccg
     7501 tgagctgaaa ccacacgacc gtactgtaga cgtgacgatc cgccgtattc gtaaacattt
     7561 cgaatctacg ccggatacgc cggaaatcat cgccaccatc cacggtgaag gttatcgctt
     7621 ctgtggtgat ctggaagatt aatcggcttt accaccgtca aaaaaaacgg cgctttttag
     7681 cgccgttttt atttttcaac cttatttcca gatacgtaat tgatcgtcca ttgtaacttc
     7741 tttactggct ttcattttcg gcagtgaaaa cgcataccag tcgatattac gggtcacaaa
     7801 catcatgccg gccagcgcca ccaccagcac actggttccc aacaacagcg cgctatcggc
     7861 agagttgagc agtccccaca tcacaccatc cagcaacaac agcgcgaggg taaacaacat
     7921 gctgttgcgc cagcctttca ataccgcctg caaataaata ccgttcatta acgccccaat
     7981 cagactggcg attatccatg ccacggtaaa accggtatgt tcagaaagcg ccagcaagag
     8041 caaataaaac atcaccaatg aaagccccac cagcaaatat tgcattgggt gtaagcgttg
     8101 cgcggtgagc gtttcaaaaa caaagaacgc cataaaagtc agcgcaatca gcagaatggc
     8161 atacttagtc gcccggtcag ttaattggta ttgatcggct ggcgtcgtca ctgcgacgct
     8221 aaacgcgggg aagttttccc agccggtatc attgcctgaa gcaaaacgct caccgagatt
     8281 atttgcaaac cagctgcttt gccattgcgc ctgaaaacct gactcgctaa cttcccgttt
     8341 ggctggcaaa aaatcaccta aaaaactggg atgcggccag ttgctggtta aggtcatttc
     8401 gctattacgc ccggcaggca ccacagaaag atcgccggta ccgcttaaat tcagggccat
     8461 attcagcttc aggttctgct tgcgccagtc cccttcgggt aaagggatat gcacgccctg
     8521 cccgccttgc tctaacccgg taccgggttc gatggtcagc gctgttccgt taacttcagg
     8581 cgctttcacc acaccaatac cacgcgcatc cccgacgcta atcacaataa atggcttgcc
     8641 taaggtgata tttggtgcgt cgagttcgct aagacgcgaa acatcgaaat cggcttttag
     8701 cgttaaatca ctgtgccaga cctgaccggt ataaatccct atcttgcgtt cttcaacgtt
     8761 ctgattgcca tcaaccatca atgactcagg taaccaaaaa tggataaaac ttcgtttccg
     8821 ctccacggtt ttatcgtctt cctgcaccgt ataaagctcg gtcacaggaa tagcgatgag
     8881 cggcccaacg agtttttgcg gcccgctggt actttggcga atcgcatctt ccacatcgct
     8941 acggtaatcg gcacgttcga caatcacctg ccgaatcagc attatcggaa tcaacaacag
     9001 caatactgca ccaaacaggg tggtcatttt ccagaacagg ggggatttca acatagtctt
     9061 ctcctttgca atggcagcag gatacgaagg ctatgtggga agaatttgaa gctatgtgaa
     9121 gtgacggtga agtcgaagcg aggccagcac gccaccttcc tgcacgttgc gcagcgtgac
     9181 ttcgccgtta aacaaacggg cgacctcact gacgaacgcc aaccccagac cgctgctttt
     9241 ttgcccattt gcacgcggca aagagtaaaa gcgttcaaaa atacgtgaca gcgcgtagtc
     9301 aggaatacca ctaccggtat ccagcacctt aagcgtgacg tgttcctgat ccacttcggc
     9361 gcttagcgtt atacgaccgc tctcgggggt aaaatcgatg gcgttatcca gtaaattccc
     9421 cagcgcctga tccagtaacg ccggttcagc agcaacatta acctcggtgg gcgtaacatg
     9481 tagagtgatg tttttttctg ccaactgcac ggtgcgcgct tcgctgacgc ggcggaataa
     9541 tgccgccaca tcaacagcag tcaaaacgac ttcctgacga ttctccagtc ttgcctggcg
     9601 tagtaacgtt tccaccagtg cctgcattcg cgcattttgc gtcagaatgt tgtcagtaaa
     9661 acgagccact acttcaggcg gcggaccttc gcgtaaaatt tccgccgcgc cacgaatcgc
     9721 cgccagtggg ctttttagct catgggttaa cgcataaaca tactgctcaa tatagttttt
     9781 cccttccagc ttcacgcgca tactttccag cgcctgcgcg agtttacgca gctcgctact
     9841 accgagatcg ggaagaggaa cgggcttatt gtcagtgacg gaatcagcat agcgagtgag
     9901 ccgggcaatg gagcggttga tccaccaaac catgcctgcg ccaatcacca gtgcgatccc
     9961 caacaaaatg gcgctggccc ataaaattcg ccgctcgctg cgtttaatga ccggagccat
    10021 cgccgcgttc ggtttgccta cgctcaaaac gccaataagc cgcgagccgt ccataatcgg
    10081 cgcggcaaca tacatcaccg aactttcggg atcggcagga ttttgcaacg tgctgcgcgc
    10141 accatactga ccacgcaacg ttagccagac gtcattccag cgcgaataat cctgcccaac
    10201 ggctttattt gccgaatcga acaatacttt accctgcgaa tcggtcatat agacatgata
    10261 ttcattgcgc actttgttaa tgccaccgat attggcgcga aacgggcgat gttgtagctg
    10321 attaaacgcc tgcgccagtt gcccatgcgt tgggtcccca gagagcaaat cgggacgcgc
    10381 cagctccgcc agcaacgttg cggtatcgat taacgtcccc tccgttgctc ttcgcacgcc
    10441 cggtttaact tctttgacaa aaatagccag tacgaaccag gccgccaccg ccaccagtaa
    10501 aaaatagccc agcagcaacc gcatgccgat acgcattaca ggcccctcag gctatatccc
    10561 atgccgcgat gagtattaat cggtgaaaga tcggggttga tggcgcgcag cttggcacgc
    10621 aacgttttaa tgtgggtatc aacggtgcga tcgtaggtgt cctgcgcatc ttcccacacg
    10681 ctatccatca gttgctggcg ggaccagacg cggcctggcg acttgagtaa cgtcttcagc
    10741 aataaaaact cataccgcgt cagcgttaat ggcgtgtcaa accagctgat ctgcgccgcg
    10801 ggttcattca attcaaaatg accaatacgg atgacgggag acggcgacga gaacttcttc
    10861 acccgacgca gtaaggtgcg caccctggcg cacacttcgc ggggtgaaaa cggtttagcc
    10921 acatagtcgt cagcgccaat ttccagccca agcaggcgat cgacctcttc acttcgggcc
    10981 gtcaggaaca gtacaggtaa cgccggatgg agcgccagta actggcggca taattcaaag
    11041 ccgctgatat caggcaaacc aacgtcgaga atcatgacgt cgggaaccag ctggcgagct
    11101 ttatccagca ccggcaagcc tcgctcaaag acctcgacgg caaaaccttc ctgctgcaac
    11161 atgtagacca gcgtgtcggc tatcccttgc tcatcttcca ctaaccagac cgtttcccgt
    11221 tgcataaatc gcctctgtta ttgccgccac ggcatgacag gaaccgcgct aatcgcgttt
    11281 ttcggcgaac cttctacaac tttgtcggag taagccagat aagcgagcgc gttgcgttta
    11341 gcatcataaa agcgcacgac ctgtaacgac ttaaagacca gggacgtacg ttttttgaat
    11401 actacctcgc cctgagcttt gccgttttta atacgatccg acagttcaat cggcccgact
    11461 tgctgacaag aaatggccgc atcggaggta tcttccgcca ggcccaatcc ccctttaata
    11521 cccccggttt tcgcccggct cacataacag gtgacatttt tcacatcggg atcgtcaaag
    11581 gcttccacaa caattttgtg atccgggccg atcattttaa atacggtgtc gaccgaacca
    11641 atctcttctg catgagccaa tggccccagc attatcaggc ttaaagacag gatcaaatgc
    11701 ttgtatttca tattgttacc atttttatct attacacgag caattagttc gtcacggtaa
    11761 ataacatatt gattaagaac aaaatctcaa tacttttatt tccgtcaagc cctaaaacat
    11821 actctactaa gaaaaaaaca ctgaatgcta aaacagcaaa aaatgctatt atccaattac
    11881 ctgatgtcag gtgctcgttg ttgaaaggat gaggatattt tatggatcag gccggcatta
    11941 ttcgcgacct tttaatctgg ctggaaggtc atctggatca gcccctgtcg ctcgacaatg
    12001 tagcggcgaa agcaggttat tccaagtggc acttacagag aatgtttaaa gatgtcactg
    12061 gccatgctat tggcgcgtat attcgtgctc gtcgtttgtc gaaatcggcg gtcgcactac
    12121 gcctgactgc gcgtccgatt ctggacatcg cgctgcaata ccgcttcgac tctcaacaga
    12181 catttacccg cgcattcaag aagcagtttg cccagactcc tgcactttac cgccgttctc
    12241 ctgaatggag cgcctttggt attcgcccgc cgctacgtct gggtgaattc acaatgccag
    12301 agcacaaatt tgtcaccctg gaagatacgc cgctgattgg tgttacccag agctactcct
    12361 gttcgctgga gcaaatctct gatttccgcc atgaaatgcg ttatcagttc tggcacgatt
    12421 ttctcggcaa cgcgccgacc attccgccag tgctctacgg cctgaatgaa acgcgtccga
    12481 gtcaggataa agacgacgaa caagaggtat tctataccac cgcgttagcc caggatcagg
    12541 cagatggcta tgtactgacg gggcatccgg tgatgctgca gggcggcgaa tatgtgatgt
    12601 ttacctatga aggtctggga accggcgtgc aggagtttat ccttacggta tacggaacgt
    12661 gcatgccaat gctcaacctg acgcgccgta aaggtcagga tattgagcga tactacccgg
    12721 cagaagacgc caaagcggga gatcgcccaa ttaatctgcg ctgtgaactg ctgattccga
    12781 tccgtcgtta acgctgcaac tcatctaatg caggggcgtc cagatgcgag atgtcccctg
    12841 cggtttcaac aacccagcca gacgccagcc acaggctttc ctgataatcc acgcgcgaaa
    12901 tagaacagtt acgcagacgt aagcggcgct ctgcccatgc tggtaatccg agaatcgtac
    12961 tcaccagaca tcccagtgca ataccatggc tcaccagcag cggtcggctt ccctgcggta
    13021 agtcccggca agattccagt gccgcattga cgcgatcgct gagctcctgc attgactcgc
    13081 cttcaggaat acgcccgtca acggtgccat tgaccagctg ccgacgccag ttctcttctt
    13141 cttcggtcag agaatcgata tgtctttttt ccagcacacc catgtttaat tcacgcaggc
    13201 gagaatcaaa gatgatgtca cagccgcagg cctgggcgat gatttccgcc gtacgccggg
    13261 tgcgtcctaa atcgctactg atgatatgcg taatgccaag ctctttggca cgggttgcca
    13321 cctgcatcgc ctgttgctca cctttggcgg tcagcgggct gtcagactgg ccctgaatac
    13381 gtcgctcggc gttccactgc gtttcaccgt ggcggactag gtatacctgt aacatgcttt
    13441 ttttccgtat actgctgtaa cgttaatttt ctgagtaatg ctgattatgc accaagttgt
    13501 ctgtgcgacc accaatcccg ctaaaattca ggccattctg caggcatttc acgagatctt
    13561 cggcgaagga tcctgccata ttgcatccgt tgccgtcgag agcggtgtac cggaacaacc
    13621 ctttggcagt gaggaaacgc gcgctggcgc acgaaatcgg gtagcaaatg cccgccgttt
    13681 acttccagag gctgattttt gggtggcgat tgaagctggc atcgatggtg acagcacttt
    13741 cagttgggtg gtgattgaaa acgccagcca gcgcggcgag gcgcgttcgg ctactttgcc
    13801 gttgcctgcg gtgattctgc agaaagtgcg tgaaggtgag gcacttggtc ccgtaatgtc
    13861 gcgttatacc ggtattgatg agattggtcg taaggaaggg gcgatcggcg tgtttaccgc
    13921 cgggaaactc actcgcgcca gcgtctatca ccaggcggtg atcctggcgc tgagtccgtt
    13981 tcataatgcg gtgtattaag cgcctgatgc gacgctgacg cgtcttacca ggctacaaaa
    14041 tcaatcgctt ttcagcaaca cctcttccag ccactggcgc agctcgacag gcgcggcttt
    14101 caggctgtta gatccacgcg taatcgtcgc gatgcccgcg ccgagttcat tttttaactc
    14161 acgctggctc atttcgcctc gcagcagctc ttcgacaata cgcacgcgag tccccaacgc
    14221 ttcgcgctca tctggcgtca gcatcaggtt taacaacggt aaatggagat cgttttggta
    14281 ggcattctta agcaggtcga caaaacgtaa ccactcctgg tgacgctgtt ctgccatcgc
    14341 tgctgaatag ggtgattgtt gggccataat atgtcgccat tgttagcggg ggaagcaaaa
    14401 tgcctccccc ggttgtactc gctaaagagt acgatagcat atcataaacg tgcggatcag
    14461 taacgacgtc cccattccgt ggcgctcatc aacgtcggtt tatcccccat gaaatagcgg
    14521 tagtaagcgt cataagccag cacgttcttc acataaccgc gcgtctcgga gaacggaata
    14581 ctctcgacaa atgccactgc gtcgatacgc ccggcgctgt tgccaagcca ggttcgcacc
    14641 cgccctggtc cggcgttata agctgctgag gagaaaatac ggttattgcc aaactgctga
    14701 taaacatatt gcagataact ggtgccaatg ttgatattcg tttccggatc cagcaattgc
    14761 ccagggctac tataaccggg aatagagaac atcttcaccg tatgggtcgc tgtaccaggc
    14821 ataatctgca tcaggccgct ggcccctacc ggtgatttca cttttggatt ccaggcgctc
    14881 tcctgacggg caatcgccat cgcatagctt tgcgggatct ccttaccgct ggtgtagcgt
    14941 ttgaaaagat cgttgtaagc cagcgggaat cgctcttcca gatgatccca tagcttcccg
    15001 gcgatcgttg cctgaacgct aagatcccac cattggttgt tgaaagcata ccgcgccagt
    15061 tgagcctgct ctgtttttga cttgctcttc accagattgg cccactcgct acgcgcggtg
    15121 ttatcgagat tccagtacat caactcgcgc acgcgcgcca tctccggccc ctgagtcagg
    15181 gcgctgtcaa cattctgcgg cgctttatca atcttcagct catactcttc tccgatgcgt
    15241 tgtgctgcaa ccatcgggta gaaaccacgc tgttgcatga gttgatgcaa aatctctttc
    15301 gcttcagctt cacgtccgcg ttccagcaat aaatccgcct gccagtaacg ccattcatct
    15361 ttctcttttg cttccatcgg cagacgcgcc agccaggtat tcaggccgcg acgatcgccg
    15421 gtgccaagtg ccattcgcac acggcgttca atcaacgacg tggattgcga gcgcataatg
    15481 gcgtcatcgc gccatttcgc ctgctcgtcg gtgacatcgt tgcccatcaa acgccaggcg
    15541 acgatatcgc gcagctcctg aatctgatct tcattaagct gctgcgcctg ggcaagcgac
    15601 gggatcatca gccgtgcatt ttcagcatcc tgccgcgcca cactggcaaa cgccaccgct
    15661 gccatttgac gggtaaaatc ggtcgctccg gttgtacgcg cgaaggtcag taccgtatta
    15721 gggttgttcg ccagtgaaat gattgccgag gcgatagtct ggtaatcggc aggcatctgc
    15781 cctgccagca ctgttaccag gccagtgtta cccgctttca tcgccagacg gatacgctct
    15841 aaatacgcca gcggatcttg tttacctgac gcacgccaga cgctaaataa cttgtcacag
    15901 gcgttaggct ggctcttgcc ggttagccac agctctttcg ccccttgcca ggcttcttca
    15961 ctctgcccgg tgttccattt cgcatagtag taattacatt gcgcttcggt agttccgggc
    16021 ttttccgggc taaaggctaa caagccacgc cagtcttcac gccgcgccag ttcattgacg
    16081 aaacgagatt gcagcgtgcg agcgggagga agcgtggggt tagcgcgaac aaagttagtg
    16141 accgtcaccg ccggttgatt catcagatca tcggtgatct ggcggtattc caggtaggga
    16201 taaagcggat aatccttcag tccaggcatc atttgttcga ccacatccat ttgtcgatta
    16261 tcccaggcct gcttgatttg cgcgtaacgg ctacgctgct catccagtga gtcggctcgc
    16321 gccacgctgc tgaccgtcag cagacagaca ccggcagcca acagccgcca ggtaacttgt
    16381 ttggcttttt ccacaagcgc atcctctaag tgtaaataca tcaatgcagc gtcatgccgc
    16441 gtaatagatt tatgctaacc agtcattgcc gtttacgcca cgttacggac acttttttac
    16501 ttttactgcg aaggtgatcg accaactggg attaggcggg gaaaaaggct acacttcgcc
    16561 tttgaaaact catcatcacg ataaacatag aggcgaagtc caacgtggct caattcgttt
    16621 ataccatgca tcgtgtcggc aaagttgttc cgccgaaacg tcatattttg aaaaacatct
    16681 ctctgagttt cttccctggg gcaaaaattg gtgtcctggg tctgaacggc gcgggtaagt
    16741 ctaccctgct gcgcattatg gcgggcattg ataaagacat cgaaggtgaa gcgcgtccgc
    16801 agccagacat caagattggt tacctgccgc aggaaccgca gctgaacccg gaacacaccg
    16861 tgcgtgagtc cattgaagaa gcggtttctg aagtggttaa cgccctgaaa cgcctggatg
    16921 aagtgtatgc gctgtacgcc gatccggatg ccgattttga caagctggcc gctgaacaag
    16981 gccgtctgga agagatcatt caggctcacg acggtcataa cctgaacgta cagctggagc
    17041 gtgcggcgga tgcgctgcgt ctgccagatt gggacgcgaa aatcgctaac ctctccggtg
    17101 gtgagcgtcg tcgcgtggcg ttgtgccgcc tgcttctgga aaaaccagac atgctgctgc
    17161 tcgacgaacc gaccaaccac ctggatgccg aatccgtggc ctggctggaa cgcttcctgc
    17221 acgacttcga aggcaccgtt gtggcgatta ctcacgaccg ttacttcctc gataacgttg
    17281 caggctggat cctcgaactt gaccgcggtg aaggtattcc gtgggaaggc aactactcct
    17341 cctggctgga gcagaaagat cagcgcctgg cgcaggaagc ttcacaagaa gcggcgcgtc
    17401 gtaagtcgat cgagaaagag ctggagtggg tacgtcaggg aactaaaggc cgccagtcga
    17461 aaggtaaagc acgtctggca cgctttgaag agctgaacag caccgaatat cagaaacgta
    17521 acgaaaccaa cgaactgttt attccacctg gaccgcgtct gggcgataaa gtgctggaag
    17581 tcagcaacct gcgtaaatcc tacggtgatc gcctgctgat tgatgacctg agcttctcga
    17641 tcccgaaagg ggcaatcgtc gggatcatcg gtccgaacgg cgcgggtaaa tcgaccctgt
    17701 tccgtatgat ctctggtcag gaacagccgg acagcggcac catcacttta ggtgaaacgg
    17761 taaaactggc atcggttgat cagttccgtg actcaatgga taacagcaaa accgtttggg
    17821 aagaagtttc cggcgggctg gatattatga agatcggcaa caccgagatg ccaagccgcg
    17881 cctacgttgg ccgctttaac tttaaagggg ttgatcaggg taaacgcgtt ggtgaacttt
    17941 ccggtggtga gcgcggtcgt ctgcatctgg cgaagctgct gcaggttggc ggcaacatgc
    18001 tgctgctcga cgaaccaacc aatgacctgg atatcgaaac cctgcgcgcg ctggaaaacg
    18061 ccctgctgga gttcccgggc tgcgcgatgg ttatctcgca cgaccgttgg ttcctcgacc
    18121 gtatcgccac gcacattctg gattaccagg atgaaggtaa agttgagttc ttcgaaggta
    18181 actttaccga gtacgaagag tacaagaaac gcacgctggg cgcagacgca ctggagccga
    18241 agcgtatcaa gtacaagcgt attgcgaagt aatgcgtaaa atgccggatg cggcgtgaac
    18301 gccttatccg gcctacaaac caagaaattt caatacgttg tgaatctcca ggcctgataa
    18361 gacgcggtaa gcgtcgcatc aggcattgag caccgaatgc cggatacggc gtgaacgcct
    18421 tttccggcct acaacagcct tagtatccgc aaattcgtag cgggtcaccc gtgctgattc
    18481 ttttaaacct tgtttaatct cgacagcctc ttccagagag gttttcaact catcaaaaaa
    18541 cttattttat acctcgcctt tgagccgttt catcgcggtt atctctgctc ccccatcatc
    18601 tcccgcacca gctccacgca gcgcaggaaa cggctgtcat aatcgtcctc ttcaacccgc
    18661 acgaattcga tattgttctc ttccagcatc tccaccagca agttctggaa ctctttgcga
    18721 tccaccgaac tgccgaggct gcgtaaacca tccgccaccc acggcgtgtt gttctccagc
    18781 aggatcacca gatcgaaacg gtattcatca atcaacgcct gtacgaacgg atgctcacgc
    18841 ccttcgtact ttttgcagaa cgcctgggta gtgacaaaat cagtgtcaat aaacgccact
    18901 ttattggcat atttcactgc aaaatcaatg tattgtgcgt ggcccagcgc gattttatcg
    18961 taatcggaat actgcaatgc gatctcatca ccgccgaggt gtgaaaagac ataatcgcga
    19021 ccatattccc acgcactggt ggtattgaag atattggcaa gtttgtttac cagggtggat
    19081 ttaccgctcg actcgccacc aaggatcgcc acggtacgta caaagaacgg cttcacttcc
    19141 gtaggaatat attcccagta gcggaacggg ttttcgcgga tctgcgcacc gctgatactc
    19201 ataaaggtac gtttcggatc gaccagcacc gtatcgatca ccagatgttc catatactgt
    19261 ggcgcatcgg cttcttccga ggtgtagatc aggtccggct gaatcccctt ttcagccata
    19321 aactttttga tgccgttgct ccacacatcc cagccgtgcg gatacggctc catgccctct
    19381 tcgttgaaag catgaatgcg aatatttttc tgatatttaa aagtttgtaa taaccagcgc
    19441 agacgatccg gcaccgtggg ctgctgcgac atggcgctgt cttcaaacaa cgcgcggtcg
    19501 cgggtatcgt caaaacccat aatgatatgc agctcgtcaa cctggctaca ggcgcgctgg
    19561 ataaggtaga tatgtccggt atgcagcggg tagaacttac cgaatacgac accaatggtt
    19621 ttcttctgtc ggggaaattc aagccccaaa aaacggtgca acgcctccag cttttgcgcg
    19681 ctggggcttt taattttggc attcagtaac tggcttaaat accctttggt cataccgctg
    19741 gcatcagcta cctgctgtag cgtgcagccc tgttgcttga tggcagtttt caggtaatca
    19801 aatgacgaca tatctccctc cgtatctctc attataagtc gtcgaacacg ctaagcgcgt
    19861 cggagagttt tttaacgcca aaaatctgca tcccttccgg cgcttttttc ggtacgttag
    19921 ccgccggaac aatcgcccgg cgaaaaccgt gtttcgccgc ttctgaaatt cgttcctgac
    19981 cgctgggcac cgggcggatc tcccctgcca gcccgacttc accaaacacc accagatcct
    20041 gtggcagcgg tctgtcacgc aggctggaaa ccatcgccag cagtaacgct aaatcggcac
    20101 tggtttcggt taccttcacg ccgccgacca cgttcacaaa tacatcctga tcggccattt
    20161 gcagaccacc gtgacggtgc aagacagcca gcaggattgc cagacggttt tgttccagcc
    20221 ccactgccac gcggcgcgga ttcgccatca tcgagtgatc gaccagcgcc tgaatctcca
    20281 ccagcaacgg acgcgttcct tcccacacca ccatcacgga gctgccggag gtcacttcat
    20341 ctccgcgact taagaaaatt gccgaagggt tgctgacttc acgcagcccc tgttcggtca
    20401 tcgcgaagac gcccagctca ttcaccgcgc cgaagcggtt tttatggctg cgcaaggtgc
    20461 gaaaacggga gtcggcatca ccatccagaa gcaccgaaca gtcgatacag tgttccagca
    20521 ctttagggcc agccagcgag ccatctttgg ttacgtgccc aaccatgaca atcgccacac
    20581 cgcgcgtttt ggcgaagcgc gtcagataag ccgccgtttc acgcacctgc gccacgctac
    20641 caggcgatga ttgtacatcc gccatatgca tcacctggat cgagtcaatt accatcagtt
    20701 tcggttgctc ttcttcggca atcaggcaga tctgctcgat gctggtttcc gacaacatat
    20761 tgagattgtc agtcggcagg ccaagtcgat gagcgcgcat tgccacctgt tgcagcgact
    20821 cttcgccggt gacatacagc gttttcatct gctgggccag tttgcacagc gtttgcagca
    20881 acagcgtgga tttccccgca ccagggttac cgccaatcag aatggcactt cctggcacca
    20941 cgccgccgcc tagtacgcgg tcgaactctt taaatccggt ggaaaaacgc ggcagctctt
    21001 caaggctgat atcggagagt ttctggactt ttgccacccc ggcgctaccg gcatagccgc
    21061 tgagacgctc gttacgcgcc accgttggcg acgcagcaag acgcacctcg gtgatggtgt
    21121 tccaggcatg acaggcactg cactgcccct gccagcgcgg ataatcggcc ccgcattcat
    21181 tacaaacaaa ggcgcgtttt ggagcttttg ccacggtgta cctcgttaat gctgtgccgc
    21241 ccgcaggatg gcgggcgagc aattacttct gattcaggct gcctgagagg atgcagaata
    21301 cccccatcag gtcagcgtga cggatggtga cttccgcctt ttcattcact tttggcttgg
    21361 catggtaggc aatccccagc cctgctgctt tgatcatcgg caggtcatta gctccatcgc
    21421 caatcgccac ggtctgcgcc agcgggattt catactcctg cgcgaggcga gtcaaagttt
    21481 tcgctttgta ctgcgcgtct acgatgtcgc cgatcacatt gccggtaaat ttaccgtcca
    21541 tgatctccag ttcattggct accacggcgg tcaggcgcag cttgtcgcgc agatattcag
    21601 caaagaaagt aaagccgccg gaggcaatcg ccactttcca gcccagcgtt tccagcttga
    21661 gcaccagttg cgttaagcct ggcatcagcg gcagattttc acgcacctgt tgcagaatat
    21721 tggcgtcagc gcctttcagc gtcgccacac ggctgcgcag gctggcggta aaatcgagtt
    21781 cgccgcgcat cgcccgttcg gttacttccg ccaccatctc gcccgttccg gccagtttgg
    21841 caatttcatc aatacattca atctggatgg cggtggaatc catgtccatc accagcaaac
    21901 ccggcgtgcg caggtgcggg attttcccca gcggggcgac atccagttgc gcttcatggg
    21961 ccaggcgcgt agcccgtgcg gtgagtgaac ctgccagacg aatcacctga taatcttcca
    22021 cgcaccaggc ggcaacaatc accatcgccg cacccagttt gctctggtat tgggtcagac
    22081 gctgtttatc cagcccacga ccatacagca gccagccgct acgacctgcg tggtaatcca
    22141 gtggcatcac ttcatcacca cttaatgaaa gaggcagacc cggccataaa gagacatctt
    22201 caggcaggtc gcaccaggta atgttaggca ttaaggctcc tgtaaaatcg ttcgaagcag
    22261 ggaaaataac gcatgaggct accttgtatc cattgcttct ggcaacatta agtctcaaat
    22321 tttcaaaggg tggaagatgg ctcgcacaaa actgaaattc cggctgcatc gggcagtgat
    22381 tgtcctgttc tgtcttgcct tgttagtggc actgatgcag ggggcgtcat ggtttagtca
    22441 aaaccaccag cgacagcgta atccacagct ggaagaactg gcccgcaccc tggcgcgtca
    22501 ggtgacgctg aacgttgcac cgctgatgcg taccgactca ccagatgaaa aacgcattca
    22561 ggcgatcctc gatcagttaa cggatgaaag ccgcatcctc gacgcgggtg tgtatgacga
    22621 acaaggcgat cttatcgccc gttcaggcga aagcgtcgaa gtgcgcgacc ggctggcgct
    22681 cgacggtaaa aaagcgggcg gctattttaa ccagcagatt gtcgaaccaa ttgccgggaa
    22741 aaacggaccg ctcggctatc tgcgcctgac gctcgacacc catacgctcg ccaccgaagc
    22801 ccaacaggtg gataacacca ctaacatttt acgcctgatg ttgctgcttt cactggcaat
    22861 cggcgtagtg ctgacccgca cgctgctaca gggtaaacgt acccgctggc agcaatcgcc
    22921 cttcctgtta accgccagca aaccggtgcc ggaagaggaa gaaagcgaga aaaaagagtg
    22981 acccattact acaagaaagg aaatcgttat gtccacatta cgcctgctca tctctgactc
    23041 ttacgacccg tggtttaacc tggcggtgga ggagtgtatt tttcgccaga tgcccgccac
    23101 gcagcgcgtt ctgtttctct ggcgcaatgc cgacacggta gtgattggtc gcgcgcagaa
    23161 cccgtggaaa gagtgtaata cccggcggat ggaagaagat aacgtccgcc tggcacggcg
    23221 cagtagcggt ggcggcgcgg tgttccacga tctcggcaat acctgcttta cctttatggc
    23281 tggcaagccg gagtacgata aaaccatctc cacgtcgatt gtgctcaatg cgctgaacgc
    23341 gcttggcgtc agcgccgaag cgtccgggcg taacgatctg gtggtgaaaa ccgccgaagg
    23401 tgaccgcaaa gtctcaggat cggcctatcg cgaaaccaaa gatcgtggct tccaccacgg
    23461 caccttgctg ctcaatgccg accttagccg cctggcaaac tatctcaatc cggataaaaa
    23521 gaaactggcg gcgaaaggca ttacctcagt gcgttcccgc gtgaccaacc tcaccgagct
    23581 gctgccgggg atcacccatg agcaggtttg cgaggccata accaaggcct ttttcgccca
    23641 ttatggcgag cgtgtagaag cggaaatcat ctccccggac aaaacgccag acttgccaaa
    23701 cttcgccgaa acctttgccc gtcagagtag ctgggaatgg aacttcggtc aggctcctgc
    23761 attctcgcat ctgctggatg aacgctttag ctggggcggc gtggaactgc atttcgacgt
    23821 tgaaaaaggc catatcaccc gcgcccaggt gtttaccgac agcctcaacc ccgcgccgct
    23881 ggaagccctc gccgggcgac tgcaaggcgg cctgtaccgc gcggatatgc tgcaacaaga
    23941 gtgcgaagcg ctgttggttg acttcccgga ccaggaaaaa gagctacggg agttgtcgac
    24001 gtggatagcg ggggcggtaa ggtaactcgc tgattaaaat accaaaggaa gggaatatga
    24061 tcgatctgga aaaccaggag cgggagatta tcaatataat gttaagccag cgtatttcct
    24121 ggctagccgc cgtgcgtatc aggcataaat tatcgcttgc tgaagtaagt aaaatgttag
    24181 gtatctcgat taattctcta aaatagatcg aaaagacgga acggtttagc tcaaacatca
    24241 aaagcaaaat ggcagaaatt tatggttgtc caccagagtt gctgatatgc ccttcctgga
    24301 tgacggctga acataaa
//
LOCUS       DAPGUL010000066        24310 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.066, whole genome shotgun sequence.
ACCESSION   DAPGUL010000066 DAPGUL010000000
VERSION     DAPGUL010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24310
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.066"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            319..405
                     /gene="leuL"
                     /locus_tag="RHX21_002838"
     CDS             319..405
                     /gene="leuL"
                     /locus_tag="RHX21_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leu operon leader peptide"
                     /protein_id="HDV1987997.1"
                     /translation="MTHIVRFIGLLLLNASSLRGRRVSGIQH"
     gene            498..2069
                     /gene="leuA"
                     /locus_tag="RHX21_002839"
     CDS             498..2069
                     /gene="leuA"
                     /locus_tag="RHX21_002839"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HDV1987998.1"
                     /translation="MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVME
                     VGFPVSSPGDFESVQTIARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIAT
                     SPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAIN
                     AGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAV
                     HAGARQVEGAMNGIGERAGNCSLEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQI
                     CNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGR
                     AAVKHRMDEMGYKESEYNLDNLYDAFLKLADKKGQVFDYDLEALAFIGKQQEEPEHFR
                     LDYFSVQSGSNDIATAAVKLACGEEVKAEAANGNGPVDAVYQAINRITDYNVELVKYS
                     LTAKGHGKDALGQVDIVANYNGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKE
                     LQRKAQHNENNKETV"
     gene            2069..3160
                     /gene="leuB"
                     /locus_tag="RHX21_002840"
     CDS             2069..3160
                     /gene="leuB"
                     /locus_tag="RHX21_002840"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HDV1987999.1"
                     /translation="MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYD
                     VGGAAIDNHGQPLPPATVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHF
                     KLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEK
                     AFDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPD
                     VELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQG
                     FGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDADDAACAIERAINRALEEGI
                     RTGDLARGAAAVSTDEMGDIIARYVAEGV"
     gene            3163..4563
                     /gene="leuC"
                     /locus_tag="RHX21_002841"
     CDS             3163..4563
                     /gene="leuC"
                     /locus_tag="RHX21_002841"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HDV1988000.1"
                     /translation="MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGL
                     RAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNH
                     PYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ
                     GRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMT
                     LCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTV
                     VTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPL
                     TEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLD
                     KIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMA
                     AAAAVTGHFADIRNIK"
     gene            4574..5179
                     /gene="leuD"
                     /locus_tag="RHX21_002842"
     CDS             4574..5179
                     /gene="leuD"
                     /locus_tag="RHX21_002842"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HDV1988001.1"
                     /translation="MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLF
                     NDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVI
                     APSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTY
                     RFTIDAFRRHCMMNGLDSIGLTLQHDDAIAAYEAKQPAFMN"
     gene            complement(5228..6406)
                     /gene="setA"
                     /locus_tag="RHX21_002843"
     CDS             complement(5228..6406)
                     /gene="setA"
                     /locus_tag="RHX21_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter SetA"
                     /protein_id="HDV1988002.1"
                     /translation="MIWIMTMARRMNGVYAAFMLVAFMMGVAGALQAPTLSLFLSREV
                     GAQPFWIGLFYTVNAIAGIGVSLWLAKRSDSQGDRRKLIIFCCLMAIGNALLFAFNRH
                     YLTLITCGVLLASLANTAMPQLFALAREYADNSAREVVMFSSVMRAQLSLAWVIGPPL
                     AFMLALNYGFTVMFSIAAGIFTLSLVLIAFMLPSVARVELPSENALSMQGGWQDSNVR
                     MLFVASTLMWTCNTMYIIDMPLWISSELGLPDKLAGFLMGTAAGLEIPAMILAGYYVK
                     RYGKRRMMVIAVAAGVLFYTGLIFFHSRMALMTLQLFNAVFIGIVAGIGMLWFQDLMP
                     GRAGAATTLFTNSISTGVILAGVIQGAIAQSWGHFAVYWVIAVISVVALFLTAKVKDV
                     "
     gene            complement(6508..6639)
                     /gene="sgrT"
                     /locus_tag="RHX21_002844"
     CDS             complement(6508..6639)
                     /gene="sgrT"
                     /locus_tag="RHX21_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake inhibitor SgrT"
                     /protein_id="HDV1988003.1"
                     /translation="MRQFYQHYFTATAKLCWLRWLSVPQRLTMLEGLMQWDDRNSES"
     gene            6728..8383
                     /gene="sgrR"
                     /locus_tag="RHX21_002845"
     CDS             6728..8383
                     /gene="sgrR"
                     /locus_tag="RHX21_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SgrR"
                     /protein_id="HDV1988004.1"
                     /translation="MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLL
                     NTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKAT
                     VRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEE
                     NGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIA
                     DIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRN
                     TTNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEG
                     CYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHART
                     IKSEKPAGLESLTLTFYQDHSEHRVIAGIMQQILASHQVTLEIKEISYDQWHEGEIES
                     DIWLNSANFTLPLDFSLFAHLCEVPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVA
                     SKAMVPLIHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP"
     regulatory      8417..8516
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            8547..9530
                     /gene="thiB"
                     /locus_tag="RHX21_002846"
     CDS             8547..9530
                     /gene="thiB"
                     /locus_tag="RHX21_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter substrate binding
                     subunit"
                     /protein_id="HDV1988005.1"
                     /translation="MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAANWGPGPVVKKAF
                     EADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSGVA
                     ADAVNVPGGWNNDTFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYQDPRT
                     STPGLGLLLWMQKVYGDDAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTS
                     PAYHILEEKKDNYAAANFSEGHYLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIP
                     TGNWMYPVANVTLPAGFEQLTKPATTLEFTPAEVAAQRQAWISEWQRAVSR"
     gene            9506..11116
                     /gene="thiP"
                     /locus_tag="RHX21_002847"
     CDS             9506..11116
                     /gene="thiP"
                     /locus_tag="RHX21_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine/thiamine pyrophosphate ABC transporter
                     permease ThiP"
                     /protein_id="HDV1988006.1"
                     /translation="MATRRQPLIPGWLIPGVSAATLVVAVALAAFLALWWNAPQGNWV
                     AIWQDSYLCHVVRFSFWQAFLSALLSVVPAIFLARALYRRRFPGRLALLRLCAMTLIL
                     PVLVAVFGILSVYGRQGWLASLCQSLGLEWTFSPYGLQGILLAHVFFNLPMASRLLLQ
                     ALENIPGEQRQLAAQLGMRGWHFFRFVEWPWLRRQIPPVAALIFMLCFASFATVLSLG
                     GGPQATTIELAIYQALSYDYDPARAAMLALLQMVCCLGLVLLSQRLSKAIAPGTTLLQ
                     GWRDPDDRLHSRICDTVLIVLALLLLLPPLLAVIVDGVNRQLPEVLAQPVLWQALWTS
                     LRIALAAGVLCVVLTMMLLWSSRELRARQKMLAGQALEMSGMLILAMPGIVLATGFFL
                     LLNNTIGLPQSADGIVIFTNALMAIPYALKVLENPMRDITARYSMLCQSLGIEGWSRL
                     KVVELRALKRPLAQALAFACVLSIGDFGVVALFGNDDFRTLPFYLYQQIGSYRSQDGA
                     VTALILLLLCFLLFTVIEKLPGRNVKTD"
     gene            11100..11798
                     /gene="thiQ"
                     /locus_tag="RHX21_002848"
     CDS             11100..11798
                     /gene="thiQ"
                     /locus_tag="RHX21_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter ATP-binding protein
                     ThiQ"
                     /protein_id="HDV1988007.1"
                     /translation="MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNL
                     IAGFLTPASGSLTIDSVDHTTTPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKL
                     NAAQQEKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSAL
                     DPALRQEMLTLVSTSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGKTNELL
                     SGKASASALLGITG"
     gene            complement(11912..12676)
                     /locus_tag="RHX21_002849"
     CDS             complement(11912..12676)
                     /locus_tag="RHX21_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001148402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDV1988008.1"
                     /translation="MQALLEHFITQSTVYSLMAVVLVAFLESLALVGLILPGTVLMAG
                     LGALIGSGELSFWHAWLAGIVGCLLGDWISFWLGWRFKKPLHRWSFLKKNKALLDKTE
                     HALHQHSMFTILVGRFVGPTRPLVPMVAGMLDLPVAKFITPNIIGCLLWPPFYFLPGI
                     LAGAAIDIPAGMQSGEFKWLLLATAVFLWVGGWLCWRLWRSGKATDRLSHYLSRGRLL
                     WLTPLISAIGVVALVVLIRHPLMPVYIDILRKVVGG"
     gene            complement(12762..13640)
                     /gene="araC"
                     /locus_tag="RHX21_002850"
     CDS             complement(12762..13640)
                     /gene="araC"
                     /locus_tag="RHX21_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose operon transcriptional regulator AraC"
                     /protein_id="HDV1988009.1"
                     /translation="MAEAQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKG
                     YILNLTIRGQGVVKNQGREFVCRPGDILLFPPGEIHHYGRHPEAREWYHQWVYFRPRA
                     YWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQIINAGQGEGRYSELLAINLLEQLL
                     LRRMEAINESLHPPMDNRVREACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQ
                     LGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEF
                     RAGCEEKVNDVAVKLS"
     gene            13979..15679
                     /gene="araB"
                     /locus_tag="RHX21_002851"
     CDS             13979..15679
                     /gene="araB"
                     /locus_tag="RHX21_002851"
                     /EC_number="2.7.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulokinase"
                     /protein_id="HDV1988010.1"
                     /translation="MAIAIGLDFGSDSVRALAVDCASGEEIATSVEWYPRWQKGQFCD
                     APNNQFRHHPRDYIESMEAALKTVLAELSVEQRAAVVGIGVDTTGSTPAPIDADGNVL
                     ALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKI
                     LHVTRQDTAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLP
                     PASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCH
                     MGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAG
                     QSAFGDIYAWFGRVLGWPLEQLAAQHPELKAQINASQKQLLPALTEAWAKNPSLDHLP
                     VVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGI
                     AVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIP
                     SAQQKMASAVEKTLQPRSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVATL
                     "
     gene            15690..17192
                     /gene="araA"
                     /locus_tag="RHX21_002852"
     CDS             15690..17192
                     /gene="araA"
                     /locus_tag="RHX21_002852"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HDV1988011.1"
                     /translation="MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKL
                     PCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQ
                     FHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERI
                     GSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVV
                     NSISDGDVNALVDEYESCYTMTPATQIHGEKRQNVLEAARIELGMKRFLEQGGFHAFT
                     TTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMED
                     YTYHFEKGNDLVLGSHMLEVCPSIAVEEKPILDVQHLGIGGKDDPARLIFNTQTGPAI
                     VASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHH
                     TVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR"
     gene            17361..18056
                     /gene="araD"
                     /locus_tag="RHX21_002853"
     CDS             17361..18056
                     /gene="araD"
                     /locus_tag="RHX21_002853"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDV1988012.1"
                     /translation="MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPS
                     GVDYSVMTADDMVVVSIETGEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHAT
                     IWAQSGQSIPAIGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDA
                     AQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKH
                     YLRKHGAKAYYGQ"
     gene            18131..20482
                     /gene="polB"
                     /locus_tag="RHX21_002854"
     CDS             18131..20482
                     /gene="polB"
                     /locus_tag="RHX21_002854"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase II"
                     /protein_id="HDV1988013.1"
                     /translation="MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAF
                     IPADQVPRAQHILQGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGGVT
                     VYEADVRPPERYLMERFITSPVWVEGDMHNGTIVNARLKPHPDYRPPLKWVSIDIETT
                     RHGELYCIGLEGCGQRIVYMLGPENGDASSLDFELEYVASRPLLLEKLNAWFANHDPD
                     VIIGWNVVQFDLRMLQKHAERYRLPLRLGRDNSELEWREHGFKNGVFFAQAKGRLIID
                     GIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLK
                     DCELVTQIFHKTEIMPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLG
                     EVPPHASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHS
                     TEGFLDAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTAC
                     RFFDPRLASSITMRGHQIMRQTKALIEAQGYDVIYGDTDSTFVWLKGAHSEEEAAKIG
                     RALVQHVNAWWAETLQKQRLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGLIQEG
                     DKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYIRETIDKLMAGELDARL
                     VYRKRLRRPLSEYQRNVPPHVRAARLADEENQKRGRPLQYQNRGTIKYVWTTNGPEPL
                     DYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFATLMTGQLGLF"
     gene            20647..23553
                     /gene="rapA"
                     /locus_tag="RHX21_002855"
     CDS             20647..23553
                     /gene="rapA"
                     /locus_tag="RHX21_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001117023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-associated protein RapA"
                     /protein_id="HDV1988014.1"
                     /translation="MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYA
                     RSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFL
                     DSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLN
                     IAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVE
                     MLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDL
                     LVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPN
                     RFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSD
                     SEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKV
                     SGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLV
                     ICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIG
                     SEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRW
                     YHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDQTEGFDDLIKNCREQHEALKAQLE
                     QGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVL
                     TPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGS
                     STISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQV
                     EFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKL
                     SAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ"
     gene            23565..24224
                     /gene="rluA"
                     /locus_tag="RHX21_002856"
     CDS             23565..24224
                     /gene="rluA"
                     /locus_tag="RHX21_002856"
                     /EC_number="5.4.99.28"
                     /EC_number="5.4.99.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA pseudouridine(32) synthase/23S
                     rRNA pseudouridine(746) synthase RluA"
                     /protein_id="HDV1988015.1"
                     /translation="MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKD
                     SVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWG
                     HPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGR
                     SHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAD
                     F"
BASE COUNT         5782 a         6631 c         6570 g         5327 t
ORIGIN      
        1 ccaaatcaat atcaaaaaaa atcgcaaaac atataattca atacaaatca tcaggatagg
       61 ttttgcaacg cgtgcatttt gtcccctttt tcctcgttga ttagatgcaa aaatttatgc
      121 tgaaatatgt caaccgatga aaagcgtcgg tagttaagca gaaattaata tcgcttactt
      181 taaccaccgc agcacaatta gctaatttta cggatgcaga actcacgctg gcgggacgtt
      241 tttattgcgt cagggttgac atccgttttt gtatccagta actctaaaag catatcgcat
      301 tcatctggag ctgatttaat gactcacatc gttcgcttta tcggtctact actactaaac
      361 gcatcttctt tgcgcggtag acgagtgagc ggcatccagc attaagccag cacgcagtca
      421 aacaaaaaac ccgcgccatt gcgcgggttt ttttatgccc gaagcgaggc gctctaaaag
      481 agacaaggac ccaaaccatg agccagcaag tcattatttt cgataccaca ttgcgcgacg
      541 gtgaacaggc gttacaggca agcttgagtg tgaaagaaaa actgcaaatt gcgctggccc
      601 ttgagcgtat gggtgttgac gtgatggaag tcggtttccc cgtctcttcg ccgggcgatt
      661 ttgaatcggt gcaaaccatc gcccgccagg ttaaaaacag ccgcgtatgt gcgttagctc
      721 gctgcgtgga gaaagatatc gacgtggcgg ccgaatccct gaaagtcgcc gaagccttcc
      781 gtattcatac ctttattgcc acttcgccaa tgcacatcgc caccaagctg cgcagcacgc
      841 tggatgaagt gatcgaacgc gctatctata tggtgaaacg cgcccgtaat tacaccgatg
      901 atgttgaatt ttcttgcgaa gatgccgggc gtacacccat tgccgatctg gcgcgagtgg
      961 tcgaagcggc gattaatgcc ggtgccacca ccatcaacat tccggacacc gtgggctaca
     1021 ccatgccgtt tgagttcgcc ggaatcatca gcggcctgta tgaacgcgta cctaacatcg
     1081 acaaagccat tatttccgta catacccacg acgatttagg cctggcggtc ggcaactcac
     1141 tggcggcggt acatgccggt gcacgccagg tggaaggtgc aatgaacggg atcggcgagc
     1201 gtgccggtaa ctgttcgctg gaagaagtca tcatggcgat taaagttcgt aaggatattc
     1261 tcaacgtcca caccgccatt aatcaccagg agatatggcg caccagccag ttagttagcc
     1321 agatttgtaa tatgccgatc ccggcaaaca aagccattgt tggcagcggc gcattcgctc
     1381 actcctccgg tatccaccag gatggcgtgc tgaaaaaccg cgaaaactac gaaatcatga
     1441 caccagaatc tattggtctg aaccaaatcc agctgaatct gacctctcgt tcggggcgtg
     1501 cggcggtgaa acatcgcatg gatgagatgg ggtataaaga aagtgaatat aatttagaca
     1561 atttgtacga tgctttcctg aagctggcgg acaaaaaagg tcaggtgttt gattacgatc
     1621 tggaggcgct ggccttcatc ggtaagcagc aagaagagcc ggagcatttc cgtctggatt
     1681 acttcagcgt gcagtctggc tctaacgata tcgccaccgc cgccgtcaaa ctggcctgtg
     1741 gcgaagaagt caaagcagaa gccgccaacg gtaacggtcc ggtcgatgcc gtctatcagg
     1801 caattaaccg catcactgac tataacgtcg aactggtgaa atacagcctg accgccaaag
     1861 gtcacggtaa agatgcgctg ggtcaggtgg atattgtcgc caactacaac ggtcgccgct
     1921 tccacggcgt cggcctggcc accgatattg tcgagtcctc cgccaaagcc atggtgcacg
     1981 tactgaacaa tatctggcgt gccgcagaag tcgaaaaaga gttgcaacgc aaagctcaac
     2041 acaacgaaaa caacaaggaa accgtgtgat gtcgaagaat taccatattg ccgtattgcc
     2101 gggggacggt attggtccgg aagtgatgac ccaggcgctg aaagtgctgg atgccgtgcg
     2161 caaccgcttt gcgatgcgca tcaccaccag ccattacgat gtaggcggcg cagccattga
     2221 taaccacggg caaccactgc cgcctgcgac ggttgaaggt tgtgagcaag ccgatgccgt
     2281 gctgtttggc tcggtaggcg gtccgaaatg ggaacattta ccaccagacc agcaaccaga
     2341 acgcggcgcg ctgttgcctt tgcgtaagca cttcaaatta ttcagcaacc tgcgcccggc
     2401 aaaactgtat caggggctgg aagcattctg tccgctgcgt gcagacattg ccgctaacgg
     2461 cttcgacatc ctgtgcgtgc gcgaactgac cggcggcatc tatttcggtc agccaaaagg
     2521 ccgcgaaggt agcggacaat atgaaaaagc gtttgatacc gaggtgtatc accgttttga
     2581 gatcgagcgt attgcccgca tcgcgtttga atctgctcgt aaacgtcgcc acaaagtcac
     2641 ctcaatcgac aaagctaacg tgctgcaatc ctctatttta tggcgtgaaa tcgtcaacga
     2701 gatcgccacg gaatacccgg atgtcgaact ggcgcatatg tacatcgaca acgccaccat
     2761 gcagctgatt aaagatccat cacagtttga cgttctgctg tgctccaacc tgtttggcga
     2821 cattctgtct gacgagtgcg caatgatcac tggctcgatg gggatgttgc cttccgccag
     2881 cctgaacgag caaggttttg gtctgtatga accggcaggc ggctcagcac cagatatcgc
     2941 aggcaaaaac atcgccaacc cgattgcgca aattctgtcg ctggcactgc tgctgcgcta
     3001 cagcctggat gccgatgatg cggcttgcgc cattgaacgc gccattaacc gcgcattaga
     3061 agaaggcatt cgcaccgggg atttagcccg tggcgctgcc gccgttagta ccgatgaaat
     3121 gggcgatatc attgcccgct atgtggcaga aggggtgtaa tcatggctaa aacgttatac
     3181 gaaaaattat tcgacgctca cgtagtgtac gaagccgaaa acgaaacccc gctgttatat
     3241 atcgaccgcc acctggtgca tgaagtgacc tcaccgcagg cgtttgatgg tctgcgcgcc
     3301 cacggtcgcc cggtacgtca gccgggcaaa accttcgcca ctatggatca caacgtctct
     3361 acccagacca aagacattaa tgcctgtggt gaaatggcgc gcatccagat gcaggagctg
     3421 attaaaaact gcaaagaatt tggcgtcgag ctgtatgacc tgaatcaccc gtatcagggg
     3481 atcgtccacg taatggggcc ggaacagggc gtcaccttgc cggggatgac cattgtctgc
     3541 ggcgactcgc ataccgccac ccacggcgcg tttggcgcac tggcctttgg tatcggcact
     3601 tccgaagttg aacacgtact ggcaacacaa accctgaaac agggccgtgc gaagaccatg
     3661 aaaattgaag tccagggcaa agccgcgccg ggcattacag caaaagatat cgtgctggca
     3721 attatcggta aaactggcag cgcaggcggc accgggcatg tggtggagtt ttgcggcgaa
     3781 gcaattcgtg atttaagcat ggaaggtcgt atgaccctgt gcaatatggc aatcgaaatg
     3841 ggcgcaaaag ccggtctggt tgcaccggac gaaaccacct ttaactatgt caaaggccgt
     3901 ttgcatgcgc cgaaaggcaa agatttcgac gacgccgttg cctactggaa aaccctgcaa
     3961 accgacgaag gcgcaacttt cgataccgtt gtcactctgc aagcagaaga aatttcaccg
     4021 caggtcacct ggggcaccaa tccaggccag gtgatttccg tgaacgacaa tattcccgat
     4081 ccggcttcgt ttgccgatcc ggttgaacgc gcgtcggcag aaaaagcgct ggcctatatg
     4141 gggctgaaac cgggcattcc gctgaccgaa gtggctatcg acaaagtgtt tatcggttcc
     4201 tgtaccaact cgcgcattga agatttacgc gcggcagcgg agatcgccaa agggcgaaaa
     4261 gtcgcgccag gcgtgcaggc actggtggtt cccggctctg gcccggtaaa agcccaggcg
     4321 gaagcggaag gtctggataa aatctttatt gaagccggtt ttgaatggcg cttgcctggc
     4381 tgctcaatgt gtctggcgat gaacaacgac cgtctgaatc cgggcgaacg ttgtgcatcc
     4441 accagcaacc gtaactttga aggccgccag gggcgcggcg ggcgcacgca tctggtcagc
     4501 ccggcaatgg ctgccgctgc tgctgtgacc ggacatttcg ccgacattcg caacattaaa
     4561 taaggagcac accatggcag agaaatttat caaacacaca ggcctggtgg ttccgctgga
     4621 tgccgccaat gtcgataccg atgcaatcat cccgaaacag tttttgcaga aagtgacccg
     4681 tacgggtttt ggcgcgcatc tgtttaacga ctggcgtttt ctcgatgaaa aaggccaaca
     4741 gccaaacccg gacttcgtgc tgaacttccc gcagtatcag ggcgcttcca ttttgctggc
     4801 acgagaaaac ttcggctgtg gctcctcgcg tgagcacgcg ccctgggcat tgaccgacta
     4861 cggttttaaa gtggtgattg cgccgagttt tgctgacatc ttctacggca atagctttaa
     4921 caaccagctg ctgccggtga aattaagcga tgcagaagtg gacgaactgt ttgcgctggt
     4981 gaaagccaat ccggggatcc atttcgacgt ggatctggaa gcgcaagagg tgaaagcggg
     5041 agagaaaacc tatcgcttta ccatcgatgc cttccgccgc cactgcatga tgaacggtct
     5101 ggacagtatt gggcttacct tgcagcacga cgacgccatt gccgcttatg aagcaaaaca
     5161 acctgcgttt atgaattaat ccccttgccc ggtcaaatga ccgggctttc cgctatcgtc
     5221 cacgtcatca aacgtcttta acctttgcgg ttaaaaataa tgcgacaaca gaaataaccg
     5281 caattaccca gtagacagca aagtgccccc aactttgtgc aattgctccc tgaataacgc
     5341 cagccagaat taccccggta gaaatactgt tagtaaataa ggtggtagct gcccccgctc
     5401 ttccaggcat taaatcctga aaccatagca tcccaatacc cgcaacaatg ccgataaata
     5461 cagcgttaaa aagttgcagc gtcatcaacg ccatacggct atgaaagaaa atcaatccgg
     5521 tgtaaaacag tactcctgcc gccactgcta tgaccatcat tcgccgctta ccataacgtt
     5581 tgacatagta gccagccaga atcattgctg gtatttccag tccagctgcc gtccccatca
     5641 ggaaacccgc cagtttgtct ggcaatccta actcgctact gatccacaac ggcatatcaa
     5701 taatgtacat ggtgttgcag gtccacatta acgtcgaggc gacaaataac atccgtacgt
     5761 tactatcctg ccagccacct tgcattgata aagcattttc cgacggcagt tctacccgcg
     5821 ccacagacgg aagcataaat gcaatcaata ccagactgag tgtgaatatc ccggcggcaa
     5881 tcgaaaacat caccgtaaag ccgtaattca acgccagcat aaaggccaac ggtggaccga
     5941 taacccatgc cagagaaagc tgcgcacgca tcaccgagct aaacatcacc acttctcgcg
     6001 ccgagttatc cgcatattcc cgcgccagag caaataactg tggcattgcc gtattggcca
     6061 gagatgccag aagcacacca caggtgataa gcgtcagata atgacgatta aatgcaaaca
     6121 atagcgcatt gccgatagcc atcaaacagc aaaatataat cagttttcgc cgatcgccct
     6181 gactgtcaga acgttttgcc aaccagaggc ttacgccgat cccagcaata gcattcaccg
     6241 tataaaagag tccgatccag aaaggttgcg cgccaacctc acgactcaga aataagctca
     6301 atgtaggagc ctgtagcgcc ccggccaccc ccatcataaa agcgaccagc ataaatgccg
     6361 cgtaaacacc gttcatacgg cgagccatcg tcattatcca gatcatacgt tcccttttta
     6421 gcgcggcgag aataaaaaaa accagcaggt ataatctgct ggcgggtgat tttacaccaa
     6481 tactcagtca cacatgatgc aggcaagtca actttcagaa ttgcggtcat cccactgcat
     6541 cagtccttca agcatggtta atcgttgtgg gacgcttaac caacgcaacc agcacaactt
     6601 cgctgtcgcg gtaaaatagt gctgataaaa ctgacgcatg gggcacctcc ttgcttcatc
     6661 gttaggaatt attgacttaa tatagggaaa ataaaattgc tgtcttttgc gcaggagttc
     6721 cccttttatg ccatctgctc gtctgcaaca acagttcatc cgcctgtggc aatgctgcga
     6781 gggtaaatcg caggacacaa cgctcaacga actggcagcg ttattgagct gctcgcgtcg
     6841 tcatatgcgt accctgctca acaccatgca ggatcgcggc tggctgacgt gggaagcgga
     6901 agtcgggcgc ggtaaacgct cgcgtctgac attcctctat accgggctgg cgcttcagca
     6961 acagcgggcg gaagacctgc tggagcagga tcgtatcgac caactagtgc agttggttgg
     7021 cgacaaagcg actgtgcggc aaatgctggt ttctcatctg ggccgcagct tccgccaggg
     7081 gcggcacatc ctgcgcgtgc tctactatcg tccgttgcgt aatctgctac ctggcagcgc
     7141 attgcgccgt tccgaaaccc atattgcccg gcaaatcttc agttcgctaa cgcgcataaa
     7201 tgaggaaaat ggggaactgg aagcagacat cgcccaccac tggcagcaaa tatcaccgct
     7261 tcactggcgt ttctttttgc gtccaggagt ccattttcat catggtcgtg aactggaaat
     7321 ggacgacgtg atcgcctctt taaaacgaat caatacgctg ccgctctatt cgcatattgc
     7381 ggacattgtg tcgccgacgc cctggacgct ggatatccat ctcacgcaac cggaccgctg
     7441 gttaccgtta ctgctgggac aagttccggc gatgatcctg ccgcgcgaat gggaaaccct
     7501 cagtaacttt gccagccatc ccatcggcac cggtccgtat gcggtgatcc gcaacaccac
     7561 caatcaactg aaaattcagg cattcgatga cttcttcggt taccgggcat taatcgatga
     7621 agttaacgtc tgggttctgc cggaaattgc cgacgagcca gctggaggtc tgatgctaaa
     7681 aggtccacag ggcgaggaaa aagagattga aagccgcctg gaggaaggtt gctactattt
     7741 actgttcgac agccgcaccc atcgcggggc gaatcagcaa gtcagggact gggtaagcta
     7801 tgtgctttct ccaactaatc tggtctattt cgctgaggaa cagtaccagc aactgtggtt
     7861 cccggcttat ggactgctcc cccgttggca ccatgcccgc accataaaga gcgaaaaacc
     7921 ggctggcctg gaaagcctca ccctgacctt ttatcaggat cacagtgagc atcgggtgat
     7981 tgccgggatc atgcagcaga ttctggcaag tcaccaggtc acgctggaaa tcaaagagat
     8041 cagctacgat cagtggcatg aaggagagat cgagagcgat atctggctta atagcgccaa
     8101 ctttacgctg ccgctggatt tttcgctgtt cgcgcacttg tgcgaggtgc cgctgctcca
     8161 acactgtatt ccgatcgact ggcaagccga cgccgcccgc tggcgcaatg gcgaaatgaa
     8221 cctggcgaac tggtgccagc aactggtcgc cagtaaagca atggtgccgc ttatccacca
     8281 ctggctgatc attcaggggc aacgcagtat gcgcggcctg cgcatgaata ccctcggctg
     8341 gttcgatttt aaatcagcgt ggtttgcgcc accggatcca tgattgctgg ttgataacaa
     8401 aatcactaca ctaacgccgt tctcaacggg gtgccacgca gacgcgtgcg ctgagaaaat
     8461 acccgtcgaa cctgatccgg ataacgccgg cgaagggatt tgaggctcct tctcaagtcc
     8521 tttgccactc ttttttgagg tgcaaagtgt taaaaaaatg tctgcccctg ctgttgctgt
     8581 gcacagcgcc cgttttcgct aaacccgttc tgactgttta tacctacgat tccttcgccg
     8641 ccaactgggg gccaggcccg gtggtaaaaa aagcctttga agccgactgt aattgcgaac
     8701 tgaaactggt ggcgctggaa gatggcgttt cgcttctcaa ccgtctgcgc atggaaggca
     8761 aaaacagtaa agccgatgtg gtgctggggc tggataacaa cctgttagac gccgccagta
     8821 aaaccggact atttgccaaa agcggcgtgg cagcggatgc cgttaacgtt cccggcggct
     8881 ggaataatga cactttcgta ccgtttgatt acggctattt cgccttcgtc tatgacaaga
     8941 acaaactgaa aaatccgccg caaagcctga aagagcttgt tgagagcgat caaaactggc
     9001 gggtgattta tcaggatccg cgcaccagta cgccggggct gggcctgctg ttgtggatgc
     9061 aaaaagtcta tggcgatgac gccccacaag cctggcagaa actggcgaag aaaacggtca
     9121 cggtcaccaa aggctggagc gaagcctacg gcctgttttt aaaaggtgaa agcgatctgg
     9181 tgctgagtta caccacctct ccggcttatc acattctcga agagaaaaaa gataactacg
     9241 ccgccgcgaa ctttagcgaa ggtcactatc tgcaggtgga agtcgccgcc cgcaccgctg
     9301 ccagcaagca gccggagctg gcgcaaaaat tcctccagtt tatggtttct ccggcttttc
     9361 agaatgcgat cccaaccggc aactggatgt atccggtggc aaacgtcacg ctgcctgccg
     9421 gttttgaaca attgaccaaa cccgcaacca cgctggagtt cacgccagcc gaagtggcgg
     9481 cacaacgtca ggcatggatt agcgaatggc aacgcgccgt cagccgttaa ttcccggctg
     9541 gttaattcca ggtgtaagcg ccgccacgct ggtggtagcg gttgcgctgg cggcgtttct
     9601 cgccctgtgg tggaacgcgc cgcagggtaa ctgggtggca atctggcagg acagctacct
     9661 gtgtcatgtg gtgcgcttct ccttctggca ggcgtttctc tcggcgctac tctctgtcgt
     9721 acccgcgata ttcctcgccc gcgccctcta tcgcaggcgc tttccgggtc ggctggcgct
     9781 gttgcgtctg tgcgcaatga ccttgatcct cccggtgcta gttgctgttt tcggcattct
     9841 tagcgtctat ggtcgtcagg gctggctggc atcgctctgc caatcgctcg gtctggagtg
     9901 gaccttttcg ccctacggcc tgcaaggcat tttgctggcg cacgtatttt ttaatctgcc
     9961 gatggcgagc cgcttattac tccaggcact ggaaaacatt cccggcgaac aacgtcagct
    10021 tgccgcccag cttgggatgc gcggctggca ttttttccgc ttcgtcgaat ggccgtggct
    10081 acggcgacaa atcccgccgg ttgccgcgct tatctttatg ctctgtttcg ccagcttcgc
    10141 caccgtgcta tcgctgggcg gcggtccgca ggcaactact atcgagctgg ctatttatca
    10201 ggcgctgagt tacgactacg atcctgcccg cgcggcgatg ctggcgctgc tccagatggt
    10261 gtgttgcctt gggctggtgc tgttgagtca gcgactaagt aaggccattg cgcccggtac
    10321 cacgctgctg caaggctggc gcgatccgga cgatcgtctg catagccgca tttgcgacac
    10381 ggtgttaata gtgctggcgc tgctgctgtt gctgccaccg ttgctggcgg tgatcgtcga
    10441 tggggtaaat cgccagttgc cggaagtgct ggcacaaccg gtgctgtggc aggcgctgtg
    10501 gacctcgttg cgtattgcgc tggcggcagg tgtattgtgc gtagtgctga ccatgatgct
    10561 gctatggagc agtcgcgaac tgcgggcgcg gcagaaaatg ctggcgggtc aggcgctgga
    10621 gatgagcggc atgttgatcc tcgccatgcc ggggattgtg ctggctaccg gcttcttttt
    10681 actgctcaac aacaccattg gcctgccgca atctgctgac ggcattgtga ttttcaccaa
    10741 tgcgttaatg gcgatccctt atgcgctgaa agtactggaa aacccgatgc gcgatatcac
    10801 cgcccgctac agtatgttgt gtcagtcgct gggcattgaa ggctggtcgc gcttaaaagt
    10861 ggtcgagctg cgcgccctga aacgtccact ggcgcaggcg ctggcttttg cctgcgtgct
    10921 gtcgattggt gattttggcg tagtggcgtt gttcggtaac gatgatttcc gtaccctgcc
    10981 gttttatctc taccagcaaa ttggctccta tcgcagccag gacggcgcgg tcaccgcgtt
    11041 aattctgcta ctactctgtt ttctgctgtt taccgtgatt gaaaaactac cggggcgaaa
    11101 tgttaaaact gactgatatc acctggcttt atcaccattt gccgatgcgt tttagcttaa
    11161 cggtagaacg cggcgagcag gtggcaatcc tcgggccaag cggcgcgggt aaaagtaccc
    11221 tgctgaattt gattgccggt tttctgacgc cagccagcgg ttcgctgact atcgacagcg
    11281 ttgatcacac cacgacgccg ccgtcacgcc gcccggtatc gatgctgttt caggagaaca
    11341 acctgttcag ccacctgacg gtcgcgcaga acatcgggct ggggcttaat ccgggattga
    11401 agctgaacgc ggcgcagcag gagaaaatgc acgctatcgc ccgccagatg gggattgata
    11461 atttaatggc gcggttaccg ggcgagcttt ccggcggtca gcgacagcgc gtggcgttag
    11521 cgcgttgtct ggtgcgcgaa cagccgattt tattgctcga tgaaccgttc tctgcgctcg
    11581 atccggcgtt acgtcaggag atgctgacgc tggtgagcac gagctgccag cagcaaaaaa
    11641 tgacgctatt gatggtgtcg cacagtgtgg aagatgcggc gcggatcgcc acacgctcgg
    11701 tggtggtcgc cgacgggcgc atcgcctggc agggtaagac caatgagttg ttgagcggta
    11761 aggcgagtgc ttcggcacta ttggggatta cgggttagta tgcactgtcg gatgcggcgt
    11821 gaacgcctta tccgacctac gggtagtgcg ttttgtaggc atgataagac gcggtcagcg
    11881 tcgcatcagg caacccgcac aagactatct cctaaccccc aaccacttta cgcaaaatat
    11941 cgatatacac cggcatcaac gggtggcgaa ttaacaccac cagcgccacc acgccgatgg
    12001 cagaaattaa cggcgtcagc cacaacaaac ggccgcgcga caaataatga cttaaacgat
    12061 cggttgcttt accgctgcgc cataaccgcc agcacagcca gccaccaacc cacaaaaata
    12121 ccgccgtcgc cagcagcaac catttaaact cgccgctctg cattccggct ggaatatcga
    12181 tcgccgcgcc cgccagaatc ccaggcagga agtaaaacgg tggccacagc aggcagccaa
    12241 taatattcgg cgtaatgaat tttgccaccg gcagatccag cattcccgcc accattggca
    12301 ccagcggacg cgtcgggcca acaaagcgac cgaccagaat ggtgaacatg ctgtgttgat
    12361 gcaacgcatg ttcagtttta tcgagtaatg ctttgttttt cttcagaaat gaccagcgat
    12421 gcaacggctt tttaaaacgc cagcccagcc agaaggagat ccagtcgccc agcagacaac
    12481 cgacaatccc tgccagccag gcgtgccaga aacttaactc gccgctgcca atcagcgctc
    12541 ccagccccgc catcagcacc gtaccgggta gaatcaaacc gaccagcgcc agcgactcca
    12601 gaaaggccac caacaccacc gccatcaatg aatacacggt agattgggta ataaagtgtt
    12661 ccagcaatgc ttgcataatg tgcctgtcaa atggacgaag cagggattct gcaaacccta
    12721 tgctactccg tcaagccgtc aattgtctga ttcgttacca attatgacaa cttgacggct
    12781 acatcattca ctttttcttc acaaccggca cggaactcgc tcgggctggc cccggtgcat
    12841 tttttaaata ctcgcgagaa atagagttga tcgtcaaaac caacattgcg accgacggtg
    12901 gcgataggca tccgggtggt gctcaaaagc agcttcgcct ggctgatacg ttggtcctcg
    12961 cgccagctta agacgctaat ccctaactgc tggcggaaaa gatgtgacag acgcgacggt
    13021 gacaagcaaa catgctgtgc gacgctggcg atatcaaaat tgctgtctgc caggtgatcg
    13081 ctgatgtact gacaagcctc gcgtacccga ttatccatcg gtggatggag cgactcgtta
    13141 atcgcttcca tgcgccgcag taacaattgc tcaagcagat ttatcgccag cagctccgaa
    13201 tagcgccctt ccccttgccc ggcgttaatg atttgcccaa acaggtcgct gaaatgcggc
    13261 tggtgcgctt catccgggcg aaagaaaccc gtattggcaa atattgacgg ccagttaagc
    13321 cattcatgcc agtaggcgcg cggacgaaag taaacccact ggtgatacca ttcgcgagcc
    13381 tccggatgac gaccgtagtg atgaatctct cctggcggga acagcaaaat atcacccggt
    13441 cggcaaacaa attctcgtcc ctgatttttc accaccccct gaccgcgaat ggtgagattg
    13501 agaatataac ctttcattcc cagcggtcgg tcgataaaaa aatcgagata accgttggcc
    13561 tcaatcggcg ttaaacccgc caccagatgg gcattaaacg agtatcccgg cagcagggga
    13621 tcattttgcg cttcagccat acttttcata ctcccgccat tcagagaaga aaccaattgt
    13681 ccatattgca tcagacattg ccgtcactgc gtcttttact ggctcttctc gctaacccaa
    13741 ccggtaaccc cgcttattaa aagcattctg taacaaagcg ggaccaaagc catgacaaaa
    13801 acgcgtaaca aaagtgtcta taatcacggc agaaaagtcc acattgatta tttgcacggc
    13861 gtcacacttt gctatgccat agcattttta tccataagat tagcggatcc tacctgacgc
    13921 tttttatcgc aactctctac tgtttctcca tacccgtttt tttggatgga gtgaaacgat
    13981 ggcgattgca attggcctcg attttggcag tgattctgtg cgagctttgg cggtggactg
    14041 cgccagcggt gaagagatcg ccaccagcgt agagtggtat ccccgttggc aaaaagggca
    14101 attttgtgat gccccgaata accagttccg tcatcatccg cgtgactaca ttgagtcaat
    14161 ggaagcggca ctgaaaaccg tgcttgcaga gcttagcgtc gaacagcgcg cagctgtggt
    14221 cgggattggc gttgacacaa ccggctcgac gcccgcaccg attgatgccg acggtaacgt
    14281 gctggcgctg cgcccggagt ttgccgaaaa cccgaacgcg atgttcgtat tgtggaaaga
    14341 ccacactgcg gttgaagaag cggaagagat tacccgtttg tgccacgcgc cgggcaacgt
    14401 tgactactcc cgctacattg gcggtattta ttccagcgaa tggttctggg caaaaatcct
    14461 gcatgtgact cgccaggaca ccgccgtggc gcaatctgcc gcatcgtgga ttgagctgtg
    14521 cgactgggtg ccagctctgc tttccggtac cacccgcccg caggatattc gtcgcggacg
    14581 ttgcagcgcc gggcataagt cgctatggca cgaaagctgg ggtggcttgc cgccagccag
    14641 tttctttgat gagctggacc cgatcctcaa tcgccatttg ccttccccgc tgttcactga
    14701 cacctggact gccgatattc cggtgggcac cttatgcccg gaatgggcgc agcgtctcgg
    14761 cctgcctgaa agcgtggtga tttccggcgg cgcgtttgac tgccatatgg gcgcagttgg
    14821 cgcaggcgca cagcctaacg cactggtaaa agttatcggt acttccacct gcgacattct
    14881 gattgccgac aaacagagcg ttggcgagcg ggcagtgaaa ggtatttgcg gtcaggttga
    14941 tggcagcgtg gtacctggat ttatcggtct ggaagcaggc caatcggcgt ttggtgatat
    15001 ctacgcctgg tttggtcgcg tactcggctg gccgctggaa cagcttgccg cccagcatcc
    15061 ggaactgaaa gcgcaaatca acgccagcca gaaacaactg cttccggcgc tgaccgaagc
    15121 atgggccaaa aatccgtctc tggatcacct gccggtggtg ctcgactggt ttaacggccg
    15181 ccgcacaccg aacgctaacc aacgcctgaa aggggtgatt accgatctta acctcgctac
    15241 cgacgctccg ctgctgttcg gcggtttgat tgctgccacc gcctttggcg cacgcgcaat
    15301 catggagtgc tttaccgatc aggggatcgc cgtcaataac gtgatggcgc tgggcggcat
    15361 cgcgcggaaa aaccaggtca ttatgcaggc ctgctgcgac gtgctgaatc gcccgctgca
    15421 aattgttgcc tctgaccagt gctgtgcgct cggtgcggcg atttttgctg ccgtcgccgc
    15481 gaaagtgcac gcagacatcc catcagccca gcaaaaaatg gccagtgcgg tagagaaaac
    15541 cctgcaaccg cgcagcgaac aggcacaacg ctttgaacag ctttatcgcc gctatcagca
    15601 atgggcgatg agcgccgaac aacactatct tccaacttcc gccccggcac aggctgccca
    15661 ggccgttgcg actctataag gacacgataa tgacgatttt tgataattat gaagtgtggt
    15721 ttgtcattgg cagccagcat ctgtatggcc cggaaaccct gcgtcaggtc acccaacatg
    15781 ccgagcacgt tgttaatgcg ctgaatacgg aagcgaaact gccctgcaaa ctggtgttga
    15841 aaccgctggg caccacgccg gatgaaatca ccgctatttg ccgcgacgcg aattacgacg
    15901 atcgttgcgc tggtctggtg gtgtggctgc acaccttctc cccggccaaa atgtggatca
    15961 acggcctgac catgctcaac aaaccgttgc tgcaattcca cacccagttt aacgcggcgc
    16021 tgccgtggga cagtatcgat atggacttta tgaacctgaa ccagactgca catggcggtc
    16081 gcgagttcgg cttcattggc gcgcgtatgc gtcagcaaca tgccgtggtt accggtcact
    16141 ggcaggataa acaagcccat gagcgtatcg gctcctggat gcgccaggcg gtctctaaac
    16201 aggatacccg tcatctgaaa gtctgccgtt ttggcgataa catgcgtgaa gtagcggtca
    16261 ccgatggtga taaagttgcc gcacagatca agttcggttt ctccgtcaat acctgggcgg
    16321 ttggcgatct ggtgcaggtg gtgaactcca tcagcgacgg cgatgttaat gcgctggtcg
    16381 atgagtacga aagctgctac accatgacgc ctgccacaca aatccacggc gaaaaacgac
    16441 agaacgtgct ggaagcggcg cgtattgagc tggggatgaa gcgtttcctg gaacaaggtg
    16501 gcttccacgc gttcaccacc acctttgaag atttgcacgg tctgaaacag cttccaggtc
    16561 tggccgtaca gcgtctgatg cagcagggtt acggctttgc gggcgaaggc gactggaaaa
    16621 ccgccgccct gcttcgcatc atgaaggtga tgtcaaccgg tctgcagggc ggcacctcct
    16681 ttatggagga ctacacctat cacttcgaga aaggtaatga cctggtgctc ggctcccata
    16741 tgctggaagt ctgcccgtcg attgccgtag aagagaaacc gatcctcgac gttcagcatc
    16801 tcggtattgg tggtaaggac gatcctgccc gactgatctt caatacccaa accggtccag
    16861 cgattgtcgc cagcctgatt gatctcggcg atcgttaccg tctgctggtt aactgtatcg
    16921 acacggtgaa aacaccgcac tccctgccga aactgccggt ggcgaatgcg ctgtggaaag
    16981 cgcaaccgga tctgccaact gcttccgaag cgtggatcct cgctggtggc gcgcaccata
    17041 ccgtcttcag ccatgcgctg aacctcaacg atatgcgcca gttcgccgag atgcacgaca
    17101 ttgaaatcac ggtgattgat aacgacaccc gcctgccagc gtttaaagac gcactgcgct
    17161 ggaacgaagt gtattacgga tttcgtcgct aagtagccac atcaggtatg taacgcctga
    17221 tgcgacgctg acgcgtctta tctggcctac acgctgcgat tttgtaggcc ggataagcaa
    17281 agcgcatccg gcattgtttt ccccctcgcc cctttgggga gagggccggg gtgaggggaa
    17341 acgacctctc aggagtcaac atgttagaag atctcaaacg ccaggtatta gaagccaacc
    17401 tggcgctgcc aaaacacaac ctggtcacgc tcacatgggg caacgtcagc gccgttgatc
    17461 gcgagcgcgg cgtctttgtg atcaaacctt ccggcgtcga ttacagcgtc atgaccgctg
    17521 acgatatggt cgtggttagc atcgaaaccg gtgaagtggt tgaaggtacg aaaaagccct
    17581 cctccgacac gccaactcac cggctgctct atcaggcatt cccctccatt ggcggcattg
    17641 tgcatacgca ctcgcgccac gccaccatct gggcgcagtc gggtcagtcg attccagcaa
    17701 tcggcaccac ccacgccgac tatttctacg gcaccattcc ctgcacccgc aaaatgaccg
    17761 acgcagaaat caacggcgaa tatgagtggg aaaccggtaa cgtcatcgta gaaacctttg
    17821 aaaaacaggg tatcgatgca gcgcaaatgc ccggcgttct ggtccattcc cacggcccgt
    17881 ttgcatgggg caaaaatgcc gaagatgcgg tgcataacgc catcgtgctg gaagaggtcg
    17941 cttatatggg gatattctgc cgtcagttag cgccgcagtt accggatatg cagcaaacgc
    18001 tgctggataa acactatctg cgtaagcatg gcgcgaaggc atattacggg cagtaatgac
    18061 tgtataaaac cacagccaat caaacgaaac caggctatac tcaagcctgg ttttttgatg
    18121 gattttcagc gtggcgcagg caggttttat cttaacccga cactggcggg acaccccgca
    18181 agggacagaa gtctccttct ggctggcgac ggacaacggg ccgttgcagg ttacgcttgc
    18241 accgcaagag tccgtggcgt ttattcccgc cgatcaggtt ccccgcgctc agcatatttt
    18301 gcagggtgaa caaggctttc gcctgacacc gctggcgtta aaggattttc accgccagcc
    18361 ggtgtatggc ctttactgtc gcgcccatcg ccaattgatg aattacgaaa agcgcctgcg
    18421 tgaaggtggc gttaccgtct acgaggccga tgtgcgcccg ccagaacgct atctgatgga
    18481 gcggtttatc acctcaccgg tgtgggtcga gggtgatatg cacaatggca ctatcgttaa
    18541 tgcccgtctg aaaccgcatc ccgactatcg tccgccgctc aagtgggttt ctatagatat
    18601 tgaaaccacc cgccacggtg agctgtactg catcggcctg gaaggctgcg ggcagcgcat
    18661 cgtttatatg ctggggccgg agaatggcga cgcctcctcg cttgatttcg aactggaata
    18721 cgtcgccagc cgcccgctgc tgctggaaaa actcaacgcc tggtttgcaa accacgatcc
    18781 cgatgtgatc atcggctgga acgtggtgca gttcgatctg cgaatgctgc aaaaacatgc
    18841 cgagcgttac cgtcttccgc tgcgtcttgg gcgcgataat agcgagctgg agtggcgcga
    18901 gcacggcttt aaaaacggcg tcttttttgc ccaggctaaa ggtcggctaa ttatcgacgg
    18961 tatcgaggcg ctgaaatccg cgttctggaa tttctcttca ttctcgctgg aaactgtcgc
    19021 tcaggagcta ttaggcgaag gaaaatctat cgataacccg tgggatcgaa tggacgaaat
    19081 tgaccgccgt ttcgccgaag ataaacctgc gctggcaact tataacctga aagattgcga
    19141 gctggtgacg cagatcttcc acaaaactga aatcatgcca tttttactcg aacgagcaac
    19201 ggtgaacggc ctgccggtgg atcggcacgg cggttcggtg gcagcgtttg gtcatctcta
    19261 ttttccgcga atgcatcgcg ctggttatgt cgcgcctaat ctcggcgaag tgccaccgca
    19321 cgccagccct ggcggctacg tgatggattc acggccaggg ctttatgatt cagtgctggt
    19381 gctggactat aaaagcctgt acccgtcgat catccgcacc tttctgattg atcccgtcgg
    19441 gctggtggaa ggcatggcgc agcctgatcc agagcacagt accgaaggtt ttctcgatgc
    19501 ctggttctca cgagaaaaac attgcctgcc ggagattgtg actaacatct ggcacgggcg
    19561 cgatgaagcc aaacgccagg gtaacaaacc gctgtcgcag gcgctgaaaa tcatcatgaa
    19621 tgccttttat ggcgtgctcg gcaccaccgc ctgccgcttc ttcgatccgc ggctggcatc
    19681 gtcgatcacc atgcgtggtc atcagatcat gcggcaaacc aaagcgttga ttgaagcaca
    19741 gggctacgac gttatctacg gcgataccga ctcaacgttt gtctggctga aaggcgcaca
    19801 ttcggaagaa gaagcggcga aaatcggtcg tgcactggtg cagcacgtta acgcctggtg
    19861 ggcggaaacg ctgcaaaaac aacggctgac cagcgcatta gaactggagt atgaaaccca
    19921 tttctgccgt tttctgatgc caaccattcg cggagccgat accggcagta aaaagcgtta
    19981 tgccggactg attcaggagg gcgacaagca gcggatggtg tttaaagggc tggaaaccgt
    20041 gcgcaccgac tggacgccgc tggcccagca gtttcagcag gagctatacc tgcgtatctt
    20101 ccgtaacgag ccatatcagg aatacatccg cgaaaccatc gacaaactga tggcgggtga
    20161 actggatgcg cggctggttt accgtaaacg ccttcgccgt ccgctgagcg aatatcagcg
    20221 taatgttccg cctcatgtac gcgccgctcg ccttgccgat gaagaaaacc aaaagcgcgg
    20281 tcgccccttg caatatcaga atcgcggcac cattaagtac gtatggacca ccaacggccc
    20341 ggagccgctg gactaccaac gttcaccact ggattacgaa cactatctga cccgccagct
    20401 acaacccgtg gcggagggaa tactcccttt tattgaggat aattttgcta cacttatgac
    20461 cgggcaactt gggctatttt gagcaaaaaa aagagttcgc cagataccat tttgatgcgt
    20521 gacgaatgct ttgccatcca gtaccatagc gccctttcca ttcctggacc tgaataacgc
    20581 cactacctca taagcacggt agcgggtggt tattgcctgc aattaaagat atagagccga
    20641 acacatatgc cttttacact tggtcaacgc tggatcagcg atacagaaag cgaattggga
    20701 cttggaaccg ttgtcgcggt ggatgcgcga actgtcactt tacttttccc atctactggt
    20761 gaaaaccgtc tgtacgcacg cagtgattcc cccgtgaccc gcgtgatgtt caaccctggt
    20821 gataccatta ccagccatga cggctggcag atgcaagtcg aagaagtaaa agaagaaaat
    20881 ggcttgctga cctatatcgg tactcgcctg gatactgaag agtccggcgt agccctgcgt
    20941 gaagttttcc ttgatagcaa actggtgttc agcaaaccgc aggaccgtct gtttgccggg
    21001 cagattgacc gtatggaccg ctttgcgctg cgttatcgcg cgcgtaagta ttccagcgaa
    21061 cagttccgta tgccgtacag cggcctgcgc ggtcagcgta ccagcctgat tccgcatcag
    21121 ctcaacatcg ctcatgatgt tggtcgccgc cacgcgccgc gcgtcctgct ggctgacgaa
    21181 gtgggtttag ggaaaaccat tgaagccggg atgatcctgc atcagcaact gctctctggc
    21241 gctgctgaac gtgtgctgat tatcgtcccg gaaaccttac agcatcagtg gctggtagaa
    21301 atgctgcgcc gtttcaacct gcgctttgcg ctatttgatg atgagcgtta tgccgaagct
    21361 cagcacgatg cttacaaccc gtttgacacc gaacagctgg tgatttgctc gctggatttt
    21421 gcccgtcgta gcaaacagcg cctggaacat ctctgtgaag ccgaatggga cctgctggtg
    21481 gtcgatgaag cgcatcacct ggtgtggagc gaagatgcgc caagccgtga atatcaggcc
    21541 attgaacaac tggcagagca cgtgccgggc gttctgctgc tgaccgcgac cccggaacag
    21601 ctggggatgg aaagccactt cgcccgtctg cgtctgctgg acccgaaccg tttccacgat
    21661 tttgcgcagt tcgttgaaga gcagaaaaat tatcgtccgg ttgcggacgc cgttgccatg
    21721 ctgctggcag gtaacaaact gagcaatgac gaactgaaca tgctcggcga gatgatcggc
    21781 gagcaggata tcgagccgct gttgcaggca gcaaacagcg acagcgaaga tgcccagagc
    21841 gcccgtcagg agctggtttc gatgctgatg gatcgccacg gcaccagccg cgtgctgttc
    21901 cgtaacacgc gtaacggtgt gaaaggattc ccgaaacgcg agctgcacac cattaaactg
    21961 ccgctaccga cgcagtatca gacggctatt aaagtctccg gcattatggg cgcacgtaaa
    22021 agtgcggaag atcgtgctcg cgatatgctc tacccggagc gtatttatca ggaatttgaa
    22081 ggtgataacg ccacctggtg gaacttcgat ccgcgcgttg agtggctgat gggctacctg
    22141 accagccatc gctctcagaa agtgctggtg atctgcgcca aagctgccac tgcgctgcaa
    22201 ctggagcagg tactgcgcga acgtgaaggt attcgcgctg cggtgttcca cgaaggtatg
    22261 tcgattatcg aacgtgaccg cgctgccgcc tggtttgccg aagaagacac cggcgcacag
    22321 gtactgctgt gctcagaaat cggttctgaa ggacgtaact tccagttcgc cagccacatg
    22381 gtgatgtttg acctgccatt caacccggat ctactggagc agcgtattgg tcgtctggat
    22441 cgtatcggcc aggcgcacga tattcagatc catgtgcctt atctggagaa aaccgctcag
    22501 tcggtgctgg tgcgctggta tcacgaaggt ctggatgcat ttgagcacac ctgcccgacc
    22561 ggacgcacta tttacgatag cgtatacaac gatctgatta actatctggc ttcaccggat
    22621 caaaccgaag gctttgacga tctgatcaaa aactgccgcg agcaacatga agcgctgaaa
    22681 gcacagctgg aacagggtcg tgaccgcctg ctggaaatcc actccaacgg tggcgaaaaa
    22741 gcccaggcac tggcagaaag cattgaagag caggatgacg ataccaacct gatcgccttc
    22801 gccatgaacc tgttcgatat tatcggtatc aatcaggacg atcgcggcga caacatgatc
    22861 gtgctgacgc cgtccgatca tatgctggtg ccggacttcc ctggcctgtc ggaagatggc
    22921 atcaccatca cctttgatcg tgaagtggcg ctggcgcgtg aagatgcaca gtttattacc
    22981 tgggagcatc cgctgatccg caacggtctg gatctgattc tttctggcga taccggtagc
    23041 agcacgattt cactgttaaa aaacaaagcg ttgccggtag gtacgctgtt ggtggaactg
    23101 atttatgtgg ttgaagccca ggctccgaag cagttgcagc tcaaccgctt cctgccaccg
    23161 acgccggtac gtatgctgct ggataaaaac ggcaacaacc tggcggcgca ggtagagttt
    23221 gaaaccttta accgccagct taacgcggtt aaccgtcaca ccggcagcaa actggttaac
    23281 gccgtgcagc aggatgttca cgctatcctt caactgggtg aagcgcagat cgagaaatct
    23341 gcccgtgcat tgattgatgc agcgcgtaac gaagccgacg aaaaactgtc tgccgagctg
    23401 tctcgtctgg aagctctgcg tgcagtgaac ccgaacattc gtgacgacga actgaccgcc
    23461 attgagagca accgtcagca ggtaatggaa agcctggatc aggcaggttg gcgtctggat
    23521 gccctgcgtt tgatcgttgt aacgcatcag taacggagcc gaaaatgggg atggaaaact
    23581 acaatccacc gcaggaaccc tggttggtta tcctgtatca ggatgaccat attatggtgg
    23641 tcaacaagcc gagcggtttg ttgtcagtgc cgggtcgtct ggaagagcac aaagacagcg
    23701 tgatgacgcg cattcagcgt gattatccgc aggcagaatc ggtgcatcgt ctggatatgg
    23761 ctaccagcgg cgtgattgta gtggcgctga ccaaagccgc ggagcgggag ttaaaacgcc
    23821 agttccgcga gcgcgagccg aaaaagcagt atgtggcccg cgtctggggg catccatccc
    23881 ccgcagaagg tctggtggat ctgccgctga tttgcgactg gccaaaccgc ccgaaacaga
    23941 aagtctgtta cgaaacgggt aaacctgcgc agacggaata tgaagtggtg gagtatgcgg
    24001 cggataacac ggcaagagtg gtgttaaaac cgattaccgg gcgttcgcat caattgcgtg
    24061 tgcatatgct ggcgctgggg catccgattc tcggcgatcg tttttatgca tcaccagaag
    24121 cgagagcgat ggcaccgcgt ttgttgctac atgcagagat gttgacgatt acccatccgg
    24181 cgtatggcaa tagtatgacg tttaaagcgc cagcggattt ttaatcgtca cgctggcgca
    24241 gttcggtagg cggataaggc gttcacgccg catccggcaa ttgtgcgccg attgcctgat
    24301 gcgacgcggg
//
LOCUS       DAPGUL010000067        24287 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.067, whole genome shotgun sequence.
ACCESSION   DAPGUL010000067 DAPGUL010000000
VERSION     DAPGUL010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24287
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.067"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..860)
                     /locus_tag="RHX21_002857"
     CDS             complement(<1..860)
                     /locus_tag="RHX21_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462448.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HDV1988016.1"
                     /translation="MKFERHHEILKRLSKFGSVKVSDLSNSLNVTKETIRSDLNELAR
                     LGYLTRCHGGAFIVLDSLDTIAKNEIAYALENYDTAQGIKKGHSTMKSQVCVIGSFNV
                     DIISYLPRLPTIGESLLASNFIFSPGGKGCNQALAASFADTDVYFITKVGTDHFSDYA
                     INFMNSSKIYKSIIYQTKETQTGTATILVNEGTGDNVIAIYPGANMTMSSDEITIQKE
                     AIINSDVILLQLETNYTALQQAITLAQKNSIPVIINPAPYNDIVNELIQDVDYITPNE
                     TEAGLLSGIDV"
     gene            complement(1056..1394)
                     /locus_tag="RHX21_002858"
                     /pseudo
     CDS             complement(1056..1394)
                     /locus_tag="RHX21_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080195.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2911..3456
                     /gene="cobU"
                     /locus_tag="RHX21_002859"
     CDS             2911..3456
                     /gene="cobU"
                     /locus_tag="RHX21_002859"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HDV1988017.1"
                     /translation="MMILVTGGARSGKSRHAEALIGDSSQVLYIATSQILDDEMAARI
                     EHHRQGRPEHWRTVERWQHLDELIHADINPNEVVLLECVTTMVTNLLFDYGGDKDPDE
                     WDYQAMEQAINAEIQSLIAACQRCPAKVVLVTNEVGMGIVPESRLARHFRDIAGRVNQ
                     QLAAAANEVWLVVSGIGVKIK"
     gene            3453..4196
                     /gene="cobS"
                     /locus_tag="RHX21_002860"
     CDS             3453..4196
                     /gene="cobS"
                     /locus_tag="RHX21_002860"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HDV1988018.1"
                     /translation="MSKLFWAMLSFITRLPVPRRWSQGLDFEHYSRGIITFPLIGLLL
                     GAISGLVFMVLQAWCGVPLAALFSVLVLALMTGGFHLDGLADTCDGVFSARSRDRMLE
                     IMRDSRLGTHGGLALIFVVLAKILVLSELALRGEPILASLAAACAVSRGTAALLMYRH
                     RYAREEGLGNVFIGKIDGRQTCVTLGLAAIFAAVLLPGMHGVAAMVVTMVAIFILGQL
                     LKRTLGGQTGDTLGAAIELGELVFLLALL"
     gene            4208..5287
                     /gene="cobT"
                     /locus_tag="RHX21_002861"
     CDS             4208..5287
                     /gene="cobT"
                     /locus_tag="RHX21_002861"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HDV1988019.1"
                     /translation="MQTLADLLNTIPAIDPAAMSRAQRHIDGLLKPVGSLGRLEALAI
                     QLAGMPGLNGIPHVGKKAVLVMCADHGVWEEGVAISPKEVTAIQAENMTRGTTGVCVL
                     AAQAGANVHVVDVGIDSAEPIPGLINMRVARGSGNIASAPAMSRRQAEKLLLDVICYT
                     RELAKNGVTLFGVGELGMANTTPAAAIVSTITGRDPEEVVGIGANLPTDKLANKIDVV
                     RQAITLNQPNPQDGVDVLAKVGGFDLVGMAGVMLGAASCGLPVLLDGFLSYAAALAAC
                     QMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMEMRLGEGSGAALAMPIIEAACA
                     IYNNMGELAASNIVLPGNTTSDLNS"
     gene            5349..6284
                     /gene="ldtA"
                     /locus_tag="RHX21_002862"
     CDS             5349..6284
                     /gene="ldtA"
                     /locus_tag="RHX21_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HDV1988020.1"
                     /translation="MMRRVNIFCSFALLFASQNSLAVTYPLPPEGSRLVGQSLTVTVP
                     DHNTQPLETFAAQYGQGLSNMLEANPGADVFLPKPGSQLTIPQQLILPATVRKGIVVN
                     VAEMRLYYYPPDSNTVEVFPIGIGQAGRETPRNWVTTVERKQEAPTWTPTPNTRREYA
                     KRGESLPAFVPAGPDNPMGLYAIYIGRLYAIHGTNANFGIGLRVSQGCIRLRNDDIKY
                     LFDNVPVGTRVQIIDQPVKYTTEPDGSKWLEVHEPLSRNRAEYESDRKVPLPVTPSLR
                     AFINGQEVDVNRANAALQRRSGMPVQISSGSRQMF"
     gene            7133..8806
                     /locus_tag="RHX21_002863"
     CDS             7133..8806
                     /locus_tag="RHX21_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-6 DNA methylase"
                     /protein_id="HDV1988021.1"
                     /translation="MLQNNPDLQSAIKRLWDKFWSSGISNPLTAIEQITYLLFMKRLD
                     ELDHKRQDEGETSGEKYISKFAGTWIPPEERNRPVAEQHPIDKRTLRWSEFKKLQPEE
                     MLQHVRDKVFPFLKDLNGAESNFTHHMKNAVFIIPKSALLVEAVKAIDEIFEMMKRDS
                     QEKGQAFQDIQGDVYEFLLSEIATAGKNGQFRTPRHIIKLMADLVQPQLGQRIADPAC
                     GTGGFLLGAYQYILTQLSLSQNLKRDNSKGSTHDEDGFFRTSVTAALTKKARILLQES
                     LYGYDIDATMVRLGLMNLMMHGIDEPHIDYQDTLSKSYSEETKYDIVLANPPFTGSID
                     RGDINENLKLSTTKTELLFVENIYRLLKKGGTACVIVPQGVLFGSGKAFKELRQTLVE
                     RCDLKAVITLPSGVFKPYAGVSTAILLFSKVFGPGDKISKPATDYVWFYEMSSDGYSL
                     DDKRNKLEGYGDLQDIIQKYHSRDEASDTDRTAKCFMVPRIDIEAENYDLSLSRYKEE
                     IFEEVQYEQPEAILERLIQAEVGNVDKKVLNKVQSGILYELLELKGMIV"
     gene            8803..10368
                     /locus_tag="RHX21_002864"
     CDS             8803..10368
                     /locus_tag="RHX21_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HDV1988022.1"
                     /translation="MNRMTIPLGDILTQSGHHRAGNRELPVLSITMKNGLVDQSDKFK
                     KRIASSDTSKYRIVYKNELVVGFPIDEGVLGFQTKYPVGIVSPAYGIWKLKDESVCHI
                     PYLERYLRSSEARRLYASRMQGVVARRRSLTKSDFLSLEVPFPPINDQARIANLLAKV
                     EGLIEQRKQLLQYLDDLLKSVFVDMFSDPVKNAKGWELTTIGELAVDVRYGTSVSAQG
                     GKYKYIRMNNITPDGYWDFENLKYIDVDNKDLDKYSLQKGDLVFNRTNSKELVGKTAV
                     YDRDETVIIAGYLIRVRFDQQTNPWFVWGHLNSKFGKAKLFNLCRNIIGMANINAQEL
                     RAIPILKPPLELQNKFATIVEKAHAIKFRYQQSLADLETLYDVVSQKAFKGELELSRV
                     PIPTQIFFPVSGEEPEHGDAVQHIAVGNYLPVTNSLPSALDNAEARKSLIEEWLEAYI
                     AQLGNSSFSVHEFMMTAQARLAELYPDVDSKFGESDYEHIKAWVFKALAIGTLKQVFN
                     DADNCIELKAVLV"
     gene            10365..12149
                     /locus_tag="RHX21_002865"
     CDS             10365..12149
                     /locus_tag="RHX21_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction system-associated AAA family ATPase"
                     /protein_id="HDV1988023.1"
                     /translation="MKLLRLKISDPSGFRSLPCGFEHYFRTEWDLQEELNQHEGFAPF
                     VCAGPNGSGKSNLLEALAAIFFQLEILRVRRSFLPEVLQSTDHDLSPISFELDYLIRV
                     PEEFRISGGQEWAKVSVWKNNGESVRFHWVNQSDFDTNADEVFKGSHADILLPQYVLG
                     YSSGENEILSLPFFKMRFVQFDEYWNALTRQLSYSGHPESRLAYLDSGFSQAILLCNL
                     LFQNETALQPFREDVGIEALREFRIIIRRSIPLAPEQLTSFASEDKNQHQSLDDILNS
                     NPALHVDMDEESGQSYHLNLMQLLEGDDKSSLVVSALKRCASLYYEDECNDTLILDYW
                     VNDATRQAFRENFNGSALALFQAFQVLLTLNLYKVSDNLKTDLYRSTSHYVSETVPTL
                     ASDERIMRFKFVRFTKQGVEEPMMLKELSDGEHQLLHSLGLCLLFRETNSLFLLDEPE
                     THFNPHWRASFITRMRQCLCNTENVEQEMLITTHTPFLISDSKPEKVLVFSKDKYSGA
                     VTISIPKYNTLGASINKITMNTFGKRETIGGHAQAVLDDLRRRFNEGIEDKETLITEI
                     DEQLGDSVEKVLLLKAIFDSDNPTNDEV"
     gene            12155..13213
                     /locus_tag="RHX21_002866"
     CDS             12155..13213
                     /locus_tag="RHX21_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988024.1"
                     /translation="MLFSYIYVPHKMEKMQAFIDFIFYEVWCKARVRGPFCLKLFEAN
                     AELYEVMEDFSSSDTQGAVFFYNHVEKIYGLFSSLTEVQIDQFKQWYQGNNDLEKICA
                     NDPSIQVVRYSDIAIHHKDIAEQLAVFFKGLYSQSLLDLAVLRAKIGDIHDHYQSFAA
                     VNKAGKCPFCGIGDIKGGNHSKREAYDHYLPKALYPFNSINFHNLAPACHECNSTYKL
                     SKDPIQSGALRRKAFNPFASVDHVIQLQITLQHANIDALEPADIIIQFGPDTLEEELE
                     TWKDLYGIEERYKAKVCAENDGKYWLTQVLDEWKEEGLSPTEFMRTLARQAKKKPYAE
                     CNFLKEPFLKACHRIGVF"
     gene            13355..13716
                     /locus_tag="RHX21_002867"
                     /pseudo
     CDS             13355..13716
                     /locus_tag="RHX21_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611473.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            14280..15227
                     /locus_tag="RHX21_002868"
     CDS             14280..15227
                     /locus_tag="RHX21_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1738 domain-containing protein"
                     /protein_id="HDV1988025.1"
                     /translation="MTISLYTSRTSAPNTAAATSVSSLEQSGSSKTKFSKTRTDIYQT
                     VTDSIIAALEAGVKPWSCPWLRVSGMSGLPSNYATGTAYSGMNIMLLWCSASKQGFSD
                     SRWMTYKQAQAAGGQVRKGEHGTTAIFYTTLEKENDAGEVEQIPMLKTFTVFNVQQID
                     GLPLTTETVSPEATFNPLPQAENLLRKSGANIIEKGQNAFFSPSTDEVWLPERHLFSD
                     AANFYATGLHELVHWSGGKKRLNREMKGKFGSADYAEEELVAELGSAFLMADLGIEGE
                     VQHESYIASWLKALKNDKRYIFKAVSAASKAHSYLMDKL"
     gene            complement(15421..16167)
                     /locus_tag="RHX21_002869"
     CDS             complement(15421..16167)
                     /locus_tag="RHX21_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein MobC"
                     /protein_id="HDV1988026.1"
                     /translation="MLISSFHERQTRNNEKIKQLLNFLKEETYSDFKTLMLLFGFRDH
                     KSLYSLLAKTERMGLIQKHVLESRTMKISLWGITSDGLAVVLTPDDKIFPPRFEPSKI
                     TGWTLEHHLDNQAARLILEKKGASGWINGDRATFLSQYQVKHRPDGLIILPGSTVIAI
                     ETERRLKTRARYQSIIASHLLARTRKLWIHVFYVIPDPQKKRALELLFDSIRHVIINH
                     QHVPLEERHRRVFRIYTLDELKRLSLDSYT"
     gene            complement(16177..18036)
                     /locus_tag="RHX21_002870"
     CDS             complement(16177..18036)
                     /locus_tag="RHX21_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraM recognition domain-containing protein"
                     /protein_id="HDV1988027.1"
                     /translation="MILNKLTASLSPIVNGMLAVLAFVQQKQLVLALLAGLTMPFFAS
                     MKSDERQKAPLWKKLIIAFSLLCFLSGTLAPVVIGSFQWLYKIRPTSDNTVLAWSVRI
                     AFTVTGIIFHIMLRRIFTPELDKIKKRLVKKTTLERELRTDVRTVKSLLPETLHYNPL
                     DYIDLNKGIFTGMGRENEPMYLPLKDWQKQHADIIGTTGAGKGVAAGILLYQSILAGE
                     GVFVMDPKDDEWAPHLYRKACEDAGKPFALIDLRKQQYQLNLIEDITPDELEELFVAG
                     FSLAEKGQESDFYRIDDRKAARIAAQFVSDNPSTTIRDVYNGDYVQSIAEKIKAFFGK
                     IEELALLNAINSPEGFSLKHIFDEGGCCYVVGSMRNSKIITAQRMLLVRLYQLAEKRD
                     RVIDVPRPIAVYLSELKYHLSRSALEGLGAARDKGVHIIMDHQSIADLKDCPADLKGD
                     AVVGAVVENAKFKLVYRVMDPDTAEWVARMSGTILVDDELRKAKTDNMLTETIDSERT
                     IRQAERFFIDSNMILNLPDFVSFIFTTKTLPSASLISPIKVRKRQLKTFSVSPDIAAT
                     VAPVKIMLDFCEDDKPAMSDVMTTHPALFFDESEVKPVKPKPDDEEHLSPLDF"
     gene            complement(18746..19051)
                     /locus_tag="RHX21_002871"
     CDS             complement(18746..19051)
                     /locus_tag="RHX21_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011172016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dpoa decarboxylase"
                     /protein_id="HDV1988028.1"
                     /translation="MINEDLFIKNIHSKNQDRISVAMVYDTLSKEAHRGCGLYYEIYE
                     SCFIGLLRDHLSELNEADANRLRRYAESKGTKIDDASYSEALEAERECRAEIYREQM"
     gene            complement(19085..19390)
                     /locus_tag="RHX21_002872"
     CDS             complement(19085..19390)
                     /locus_tag="RHX21_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDV1988029.1"
                     /translation="MKKTVIAATVLCLTAGTPIYSFAADPCEVVLCMYGKATGNSGGS
                     ECSSAERAFFKINAFKKHHRFNPGKTFDMRKEFLGECKAADPESISKILSKFGRVKG"
     gene            complement(19426..19824)
                     /locus_tag="RHX21_002873"
     CDS             complement(19426..19824)
                     /locus_tag="RHX21_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="HDV1988030.1"
                     /translation="MIKKLKVIMLAAIVTGCSSPPPPVPVEWDKAAAPLNTSLSQWSD
                     NNVIVPSPTVNGKWTSSISAQSFYDTIWTPAVFYAVAHSTRIVVTAQSGTDFFNAKNW
                     LRQNGAKGVIEYQPVFNCLTCRETTIYFSR"
     gene            complement(19821..20846)
                     /gene="virB11"
                     /locus_tag="RHX21_002874"
     CDS             complement(19821..20846)
                     /gene="virB11"
                     /locus_tag="RHX21_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="HDV1988031.1"
                     /translation="MTAKNISLDRYKQRFFGDFLELPGLTEIAVNRPGELYTKINGVW
                     EQHAVPLSYEDCYNFARCLAKHHGDNIEDIKPGLSATLESGERCQVIVPPACERDTVS
                     ITIRKPSKVQIPHQSYIDAGFYNRVTGEEKTETHDEELIALYNTKNIPLFMEKCVEYG
                     KTLAVAGETSTGKTTYMKMLIGYIPVHLRISTIEDNPEITFFIHKNYVHLFYPSESSD
                     EKGSIVTPASLLRWNYRMNPDRILLTEVRGAEAWDFLKITGSGHEGSMTSIHAGSAKE
                     AIDGFITRCYENPQCAQLPYTFMLRKVLDSLDVIVSIDLDGNVRRMNDIYFRPIHRNQ
                     YFEEMKA"
     gene            complement(20836..22086)
                     /locus_tag="RHX21_002875"
     CDS             complement(20836..22086)
                     /locus_tag="RHX21_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein"
                     /protein_id="HDV1988032.1"
                     /translation="MNDENKMPVPDEAQAFPAHAEDDIATLEREARAKREAELLNAQD
                     DEEKDPVQPAVNKLKKRKRGKATAFLAIVAVTLIFLAWGGNWVYRNILWQPTEEKKQD
                     TAPQTNKTDYRQRNDLGMSTDTAEEEPEQQDNGQSSTGGTGQVAPAAPPELNKASFLI
                     RRDGSATTQNPVKTRQQEMTLTSATTTGQQDSSAATNTAAPPPGQSPAPLRRIPYNPD
                     LYIPENTSIPCSLDRRFVSDRAGKLRCTVTTDIWSASGNTKLIEKGTTASLLYRAIAE
                     EGMKHGQGRAFIIATKLRTRQPPYLDIPLVDTSAAGELGEAGVDGWIDSHFWERFGGA
                     LMVGMIPDIGAWASNSAGKKDRNTDYTENSRQAMADMARTTLENSINIPPTLYKNQGE
                     IINLITGEDIDFSNIYILRLKNDR"
     gene            complement(22122..23030)
                     /gene="virB9"
                     /locus_tag="RHX21_002876"
     CDS             complement(22122..23030)
                     /gene="virB9"
                     /locus_tag="RHX21_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="HDV1988033.1"
                     /translation="MMKKLTFTALALMMCGAAWAAAIPQASRYDSRVQQVIYNPQNVT
                     VVNTKPGFMTTLVFDNDEAVISAKPGFDEAWEATPDANRVNVRPVALTQGAPGEDGNT
                     TQVVIPPNSRDWHTNMLVVTSKRLYNVELNVIDDKSAQQPAFQVSYRYPGEERDKASR
                     EATARQREWEQKQQQASVQKALNSAQTPRNWSYTKYPGKGSFNIVPDFAYDDGRFTFV
                     GFSPSKSIPSVTKELNGKEHVVNSSIQKKGDFTVLVIQEVTPRLVLRSGNAVVGLENS
                     GFGKVHAADGSTVSRQVERVEKPESN"
     gene            complement(23027..23710)
                     /locus_tag="RHX21_002877"
     CDS             complement(23027..23710)
                     /locus_tag="RHX21_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="HDV1988034.1"
                     /translation="MSEQKLIAESRTFEQQMIERDKRATKAGFVVGGMGLLIAVLALV
                     AVVVMLPLKQTDVELYTLDNHTGRVEHVTRTSKTSLTATEAYQKAMAANYVKVRERYV
                     YPSLQDDYETVQVYNAPQVNDDYLALYAGKNAPDKVYKNGAHTVKVEILSNQITDATA
                     PDRVATIRYKKIIRRLADNSTRNEYWDARFTFHSNPDKEMSDAEREINYFGFTVTSWQ
                     TDREIRGGE"
     gene            complement(23703..23840)
                     /locus_tag="RHX21_002878"
     CDS             complement(23703..23840)
                     /locus_tag="RHX21_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016157224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988035.1"
                     /translation="MKRLIALALLCALSGCAQNTPPSAFSGKGEPVNTPQIMAELNSH
                     E"
     gene            complement(23932..>24287)
                     /locus_tag="RHX21_002879"
     CDS             complement(23932..>24287)
                     /locus_tag="RHX21_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HDV1988036.1"
                     /translation="AGIFAAILVYISAKVAAALAGASATVSMQGLAAVGIGAAAFGAG
                     KLAGGAVKETKRSAQDNIQGWKDANAGKPGKPGGELGYNASKARKYAIEQMIARNEAR
                     RLAQSRESAVKKFNS"
BASE COUNT         6197 a         5473 c         6003 g         6614 t
ORIGIN      
        1 acgtctatgc cggacagtaa accagcttct gtttcattgg gggtgatata atcaacatcc
       61 tgaataagtt cgttgacgat atcattatag ggtgccgggt taataatgac cgggatactg
      121 tttttttgcg ccaatgtgat cgcttgttgc agagcggtat aatttgtttc gagctgcaga
      181 agtatgacat cagaattaat aatcgcttct ttctgaatag ttatttcatc ggacgacatt
      241 gtcatgttgg caccgggata gatcgcaata acattatcgc cagtaccttc attaacaagg
      301 atcgtggcag ttccggtttg cgtttctttc gtttgataaa ttatactttt ataaatctta
      361 gacgaattca taaagttgat cgcataatca ctaaagtgat ctgtacctac ttttgttatg
      421 aaataaacat cagtatcggc aaagcttgct gccagcgcct ggttacagcc ttttcccccc
      481 ggtgaaaata taaaattact tgccagaagc gattctccga tagtgggaag cctcggcaaa
      541 taactgatga tatcaacatt aaacgaacca ataacgcata cttgactttt catagttgag
      601 tggccttttt ttattccctg ggctgtatca taattttcaa gcgcataagc gatttcattt
      661 ttcgcaatag tatcaagcga gtctaggacg ataaaagcac cgccatgaca tcgagtcaga
      721 tagccaagcc tggcaagttc attaagatct gaacgaatag tttctttcgt tacattgagg
      781 ctattggaca gatcggatac ttttacagaa ccgaatttac tgagtcgttt caatatttca
      841 tgatggcgtt caaatttcat gcttcacctc acttcagtta cgttaatatc tatcgatgta
      901 tattgatgtg ataatcacca taaagtggcg gggaaaagca aaaaaaagca aaaatagcct
      961 gagaaaaggt aagcgttaat ggagaatcat attgatgctt atttattggt gagaactacg
     1021 ttccatggca ggagttcatc aatacggttg gaaggttatt ccggcagtac gctcaggata
     1081 tggcgcagat acgcttccgg atcaatgtcg ttcagaaggc aagtgccgat aagcccatac
     1141 aacagtgcac tgcgctcgcc gccgaagaac ataaagtttt tatttccgag acagatggca
     1201 caaagggctt tttccgcggc attatgtctg cctccgcctg accgtcaaca ctgtaataac
     1261 agagtgcgcc ccactgattc agtacacagc tgaaccattc tcccagtctg gatttttgga
     1321 tagcgtggca tttttctcca ccatgcatgc agtgagtcca gtaacagttt gctcttcttc
     1381 tgcctgacca caagatgtgc tggactggta aacgatgggg atacctgctt acgcgagagc
     1441 aataagtggc tggccacaat tctcggtaca aaactctgct gaatagcagc gattttccca
     1501 gcgtggtgcg tcgtttgcat tttactggtt ctaagttaac aattatctgt tcactaatga
     1561 ctactctaaa aacttgtatc aggactatca cttatttaag tgatattggt tgtctggaga
     1621 ttcagggggc cagtctataa actttttaca aaaggatgaa tgcagaaggt tactctaatg
     1681 gccagagtga tgacaatgat ggtcagacgt tgacctgcag aaactgcatt ttaattggtc
     1741 tataaagtct gcaagaggaa tcagggtcag atcagtgagt cttatcgcgg cccgaagcta
     1801 tgactgaaag aaggctggat acagaattgc aacaatttgg caatgtcaga acacagaagc
     1861 tttgcaagca ggtgaaaggt tatgtctagc aaaaggagta tatcagaata catctactga
     1921 tgtacaaaac acaacaatag cttcatgata tataaatacg tgatgacgag tggtactccg
     1981 catggttatt taacttctca gcaccactaa tgatcctgag caacttcgta tttgggccat
     2041 tgccatggag tagaaagctg tgtctgagaa tgcagaattt gagaaaagaa ttcgctttct
     2101 tggagagctt ctgaaaatgg cacgctaaca acgttttgtt aaaaaatgtg aatcacttgc
     2161 cggggctgca ttttctattc gaggagaatg ttgacgtaga tattacagaa atctcagcgc
     2221 atcaggataa actgctacct taggtcaacc accaaaagaa aatacaatac gtccagtttg
     2281 tatgccttta ataacacatc ttctaaatgt tgaagaatta tcccgcctgc tgaagaacgt
     2341 tgctctgagt gtgataaacc tttttattct tgatgatgtc agcgagaaga tggaatatat
     2401 ccccgactgg gtcgtggtta cccggttaaa catctggtgg cgctaataaa tctggcaagt
     2461 cacattctgt tgaatgctgt gacagtgcct taccgagaga gcgaaattgt ggtgttctag
     2521 tgcatagtcg ccaccattcc ggataattct attgcgttgt tttacaagtt cttttacagc
     2581 gcagatctgt cgctgacgtt gaatcaatag cctggatttc agaacacaat gcccgtttgc
     2641 tggttggtcc ggcagtagca ttaattcatt atctgaatga aatgtgtcaa tccacagaaa
     2701 ccgctgtcaa tgacacattt tgtcggacgt taacacgaga aagtctggct attccgtaat
     2761 gccatcttat ttcgtaatgg attgagaatg ctggattttt aattatatta cgcgcagtat
     2821 taatcgcgta aatgttttgc ggtcagcaac ggtgggggat ccattgttct gttcaatgaa
     2881 taccatcata catttgaatc aggagtcggt atgatgattt tggtgacggg gggcgcacgg
     2941 agcgggaaga gtcgccacgc agaggcgctt attggggact cttcacaggt tctgtatatc
     3001 gctacctcgc aaatccttga tgatgagatg gctgcacgga tagaacatca tcggcaaggc
     3061 cgcccggagc actggcgcac agtggagcgc tggcaacatc ttgatgaatt aattcatgca
     3121 gacattaacc cgaatgaggt tgtgttgctg gaatgcgtta ccacaatggt gactaatctg
     3181 ttgtttgatt atggcggcga taaagaccct gatgaatggg attatcaggc gatggaacag
     3241 gcgattaatg ctgagattca gtcgttgatt gctgcctgcc aacgttgccc cgcaaaggtt
     3301 gtattagtga ctaacgaagt gggaatgggg attgtgccgg agagtcgtct ggcacgacat
     3361 tttcgtgata ttgccgggcg ggtaaatcag cagttggccg ctgcggcaaa tgaagtatgg
     3421 ctggtggttt cgggtattgg agtaaaaatc aaatgagtaa attattttgg gcgatgctct
     3481 catttattac gcgtctgcct gtaccgcgtc gctggtccca gggactggat ttcgagcatt
     3541 attctcgcgg tattattact tttcctttaa ttggattatt gcttggcgcg attagcgggc
     3601 tggtcttcat ggtgctgcag gcatggtgtg gcgtaccact ggcggcactg tttagcgtac
     3661 ttgtgctggc gctgatgacc gggggattcc acctggacgg cctcgccgat acctgtgatg
     3721 gcgtattttc tgcacgtagc cgcgatcgca tgttggaaat catgcgtgat agccgtttag
     3781 gcacccatgg cggtctggca ttgatttttg ttgtactggc aaagattctg gtattaagcg
     3841 agttggctct gcgtggcgaa ccgatccttg catcgctggc ggcagcatgt gcggtcagcc
     3901 gcgggactgc cgcattattg atgtatcgtc atcgttatgc gcgggaagaa gggcttggca
     3961 atgtgttcat tggcaaaatt gatgggcgac aaacctgcgt cacactcggc ttagccgcta
     4021 tttttgctgc cgtattattg ccgggtatgc atggtgtggc tgctatggtg gtgacgatgg
     4081 tggcgatttt catcctcggt cagcttctca aacgtacgct gggcgggcaa accggcgata
     4141 cgctgggagc tgctatagag cttggtgaac tggtcttcct gctggcactg ctataaagag
     4201 acgtgacatg caaacacttg ccgatttact gaatacgatc cctgctatcg atcctgccgc
     4261 tatgtcgcgt gcacaacggc atattgacgg gttactcaaa cctgttggta gcctgggaag
     4321 gctggaggcg cttgccatac aactggcggg aatgccgggg ttgaatggca taccgcatgt
     4381 gggcaaaaaa gcggtactgg ttatgtgtgc cgatcacggc gtctgggagg aaggggtcgc
     4441 tatttcccca aaagaagtga cagccattca ggctgaaaat atgacccgcg gaacaaccgg
     4501 cgtgtgtgtg ctggcagcac aagcgggcgc taacgtccac gtagttgatg ttggtattga
     4561 tagtgctgag cctatccccg ggcttatcaa catgcgtgtc gcacgaggta gcggcaatat
     4621 tgcttcagct ccggcaatga gtcgccgtca ggctgaaaag ttgcttttgg acgtcatatg
     4681 ttatacgcgg gagctggcaa aaaacggtgt cacgctgttt ggtgtaggtg aactggggat
     4741 ggcaaacacg acaccggcag cggcaatagt cagcacaatc actggccggg atcctgaaga
     4801 agtggttggg attggcgcaa acctgccgac agataaactg gctaataaaa ttgatgttgt
     4861 gcgccaggcg attacgttga atcaaccaaa tccgcaggat ggcgttgatg tcctggcaaa
     4921 agtgggtgga tttgatttgg tcggaatggc tggcgtgatg ttaggcgctg cttcctgcgg
     4981 tttacccgtg ttgctggatg gatttctttc ttatgctgcc gcgctcgcag cctgccagat
     5041 gtctcctgca atcaaaccgt atctcattcc ttctcacctg tcggcagaaa aaggggcgcg
     5101 tattgcgctg tcgcatttgg ggctggagcc ttatctcaat atggagatgc gtttaggtga
     5161 ggggagtggc gcagctctgg cgatgcccat catcgaagct gcctgtgcga tatataacaa
     5221 catgggcgaa cttgctgcca gtaatattgt tctaccgggg aatacgactt ctgatttgaa
     5281 cagttaaaaa cgaaaagtct gataaaagct atacttaacg gatagctttc gcgacttagg
     5341 aaagggatat gatgcgtcgt gtaaatattt tttgctcatt tgctctgctt tttgccagcc
     5401 aaaatagcct ggcggtaact tatccattac ctccagaggg tagccgttta gtggggcagt
     5461 cgcttactgt aactgttcct gatcacaata ctcagccgct ggagactttt gccgcacaat
     5521 acgggcaagg gttaagtaat atgctggaag cgaatccggg cgctgatgtt tttttgccga
     5581 agcctggctc acaactcacc attccgcagc aactgatttt gcccgccact gttcgtaaag
     5641 ggattgtggt taacgtcgct gaaatgcgtc tttattacta tccgccagac agtaatacag
     5701 tggaagtctt tcctattggt atcggccagg ctgggcgaga aaccccgcgt aactgggtga
     5761 ctaccgttga acgtaaacaa gaagcaccaa cctggacgcc aacgccgaac acccggcgcg
     5821 aatatgcgaa acgaggggag agtttgcccg catttgttcc tgcggggccc gataacccca
     5881 tggggctgta cgcgatttat attggcaggt tgtatgccat ccacggtacc aatgccaatt
     5941 ttggtattgg gctccgtgta agtcagggct gtattcgtct gcgtaatgac gatatcaaat
     6001 atctgtttga taatgttcct gtaggcactc gtgtacaaat tattgatcag ccagtgaaat
     6061 acacaacgga acctgatggt tcaaagtggc tggaagttca tgagccgctg tcgcgcaatc
     6121 gtgcagaata tgagtctgac cgaaaagtgc cattgccggt aaccccatct ttgcgggcgt
     6181 ttatcaacgg gcaagaagtt gatgtaaatc gcgcaaatgc tgcgttgcaa cgtcgatcgg
     6241 gaatgcctgt gcaaattagt tctggttcaa gacagatgtt ttaagagcgt tgataattag
     6301 aaagtaaaaa gcctgctcga aagcaggctt ttttgaattt ggctcctctg actgggatcg
     6361 cccaagccaa taactggcta ataaataagc taaaccttgt tgctcttcct gtcaagacca
     6421 ccataatgac caccaatttc gaatgagtgt gcgacaaagc gtagatgcga tgcttattac
     6481 tacagtaaag tagaacaggc tgaggcgtcg ttatgattgg atggtaaccc tgcgtatgaa
     6541 acttggatgg ctagcacttt atccgcctac tgagtggcgg gatgcttgct tgttaagcat
     6601 aggaaaaact ctgcatttac tgtcttgaaa aaatcaatgt acataggacg tgccccacag
     6661 acatctcagg gcaatgttga tgacgtccgc tcttacacaa atcgttcaga gttggagtat
     6721 gcatttcatg tcggatatcc tgtgtgaatg gcgatgtttt ttggcactga atttagtgaa
     6781 tattttagcg ggcgtgttgg tagctctacg atttttggat aacctctttt cgggagcttt
     6841 ttagacattt acacttttaa agccttctaa tgataagttt ttgtctgttt tatctctttg
     6901 tggtagaata taatgcttat tatttggtgg tttactgaga ctcatcgccg ataggacatt
     6961 atgaatactg ttactaattg agctattttt actaaaaaac atatagttat gtcatggtgc
     7021 agccaaaatg ggctggtaag ttgccacttt aagaaaggaa aatgttctga aaaaagagta
     7081 aactgccagc cacaaagcac ctcaatagag actgaaccga gaacccagcc acatgctaca
     7141 aaacaaccct gaccttcaaa gcgcgatcaa acgcctctgg gataaattct ggagtagcgg
     7201 cattagcaat ccgctcacag ccattgaaca gattacctac ctgttgttta tgaaacggct
     7261 agatgaactc gatcataaaa ggcaagacga aggtgaaacg agtggtgaga aatacatttc
     7321 taagtttgct ggtacttgga ttccaccaga ggaaagaaac cgccctgttg cggaacaaca
     7381 ccctatagat aaacgcacgc ttcgctggag cgagttcaag aaattgcagc ccgaagagat
     7441 gctgcaacat gtgcgagaca aagtttttcc ttttctgaaa gatctgaatg gtgctgaatc
     7501 taacttcact catcacatga aaaacgcagt attcattatc ccaaagtcag cattgttggt
     7561 ggaggcagtg aaggccattg acgaaatctt cgagatgatg aaaagggatt ctcaagaaaa
     7621 aggccaagct tttcaagaca ttcaaggaga tgtatatgaa ttcctgctgt cggaaatcgc
     7681 caccgcaggc aagaacggcc aatttcgcac accacgccac attattaaat tgatggcaga
     7741 tctggtccag ccgcaactgg gacaacgtat tgccgaccct gcctgcggta cgggggggtt
     7801 tctgttaggt gcctaccagt acatccttac tcagttgtct ttatctcaaa acttaaaaag
     7861 agataattca aaaggatcta ctcatgatga agatgggttc tttcgcactt ctgtgactgc
     7921 cgctctgacc aaaaaggccc ggattctttt gcaagagagt ctgtatggtt atgacattga
     7981 cgctactatg gtgcgtttag gcctaatgaa cttaatgatg catggaattg atgagccgca
     8041 tattgattat caggacacac taagcaagag ctatagtgaa gaaaccaaat atgacatagt
     8101 gctagcaaac ccgcctttta ctggcagtat agacaggggg gatattaatg agaatttgaa
     8161 actctcaacc actaaaaccg aacttttgtt tgttgagaac atctatcgtt tgctgaaaaa
     8221 gggcggtacc gcctgtgtga ttgtgcctca aggagtattg tttggctcgg gcaaggcatt
     8281 caaagaacta cggcaaactt tagttgagcg ctgcgacctc aaggctgtca ttactctgcc
     8341 cagtggagtg tttaaaccct acgctggagt aagtactgcc attttattgt tctccaaagt
     8401 tttcgggccg ggggataaaa tttccaaacc tgctaccgat tatgtctggt tttatgagat
     8461 gtcttccgat ggttactcat tggatgacaa acgaaataag cttgaaggct acggcgacct
     8521 gcaagacatc attcaaaaat accattcccg tgatgaggcg tctgacacag atcgtacagc
     8581 taagtgtttt atggtgccaa gaatagatat tgaagcggag aattacgatc tttcgctgtc
     8641 tcgctataag gaagaaatat ttgaagaagt gcagtacgaa cagcctgaag ctattctgga
     8701 acgactaatt caagcagaag tggggaatgt ggataagaaa gtgcttaata aagtacaaag
     8761 tggcatcttg tacgagctac tagagttaaa ggggatgata gtatgaatag aatgactatt
     8821 ccccttggtg acatattaac tcaatccggt caccaccgtg caggcaatcg agagcttccg
     8881 gtcctatcaa taaccatgaa aaatggtttg gttgaccaat cagacaaatt caagaagcgg
     8941 attgccagtt cagacacgtc taaatatcgt attgtataca agaatgaact tgttgttggg
     9001 tttcctattg acgagggagt tcttggattc cagacaaaat atccggtagg aatcgttagc
     9061 ccagcttatg gtatctggaa actcaaggat gaatcggtat gccatatccc ttaccttgag
     9121 cgttatctgc gctcctccga ggcaaggcga ctctatgcat ctcgtatgca aggggttgtt
     9181 gcacgtagac gtagcttgac gaagtctgat tttcttagtt tggaagtacc ttttcctccc
     9241 atcaatgatc aggctcgtat agctaattta ttggccaagg tagaagggct aattgaacag
     9301 cgtaaacaac ttttgcaata cctggatgac ctactaaaga gcgtattcgt cgatatgttt
     9361 agtgatccgg taaaaaatgc aaaaggatgg gaactaacaa caataggtga gttagctgtc
     9421 gatgtaagat acgggacaag tgtatcagcg caaggtggaa aatataaata catacggatg
     9481 aataacatta ctccggatgg ttactgggat tttgagaatc ttaaatatat cgatgtagat
     9541 aataaggatc tggataaata ttctcttcag aaaggagatc tcgttttcaa ccggaccaat
     9601 tcaaaagaat tggttggtaa aacggcggtt tacgatcgag atgaaactgt tattattgct
     9661 ggctatctca ttcgtgttag gttcgatcaa caaactaacc cttggtttgt atgggggcac
     9721 ctgaactcaa agtttggaaa agcaaaatta tttaatcttt gtcgtaatat tattggtatg
     9781 gctaacatta atgcccaaga gttaagggcc atccctattc ttaagcctcc actggagtta
     9841 caaaataaat tcgctactat tgtagagaaa gcgcatgcta ttaaatttcg ctatcagcaa
     9901 agtcttgctg atcttgagac cctgtatgat gttgttagcc aaaaggcttt caagggggaa
     9961 ttagaacttt cgcgtgtgcc tattccgaca cagatatttt tcccggtatc aggtgaagaa
    10021 cctgaacacg gggatgccgt acaacatata gcagtgggta attatctgcc cgtaactaat
    10081 agcttaccat ccgcgttgga taatgcagag gctcgcaagt cactgatcga ggaatggcta
    10141 gaggcctata tagcgcaatt gggcaactca tcgttttcag tacatgagtt catgatgacg
    10201 gcgcaggcac ggctggcgga attatatccg gacgttgatt ctaagtttgg tgaaagtgac
    10261 tatgagcata tcaaagcttg ggtgttcaaa gctctggcta ttggtacact gaagcaggta
    10321 ttcaatgacg ctgacaattg cattgaactt aaggcggttt tggtatgaag ctattacgcc
    10381 taaaaatctc tgatccgtcc ggcttccgta gtctgccctg tggttttgaa cactatttta
    10441 gaaccgaatg ggatttacag gaagaattga atcaacatga aggctttgcg ccttttgtgt
    10501 gtgctggtcc caacggcagt ggtaaatcca atctgcttga agcattagca gctatcttct
    10561 ttcagttgga aattttgcgg gtccgtcgaa gttttttgcc tgaggtattg caaagtaccg
    10621 atcatgattt atcaccaatc tcatttgagc tggattatct aattcgagta ccagaagagt
    10681 ttcgaatctc tggcggacaa gaatgggcaa aagtctccgt gtggaaaaac aacggggaat
    10741 ctgtgcgttt ccattgggta aatcagagtg actttgacac aaatgctgat gaagttttca
    10801 agggaagcca tgccgatatt ctattgcctc agtatgtgtt gggctactcg tctggcgaga
    10861 atgaaattct cagtctaccg tttttcaaaa tgcgctttgt acagttcgac gagtactgga
    10921 atgccttgac tcgacaactg agctactctg gccatccgga gtcgaggttg gcctatcttg
    10981 acagtggttt cagccaagct attttacttt gtaatctgct ttttcaaaac gaaactgcgc
    11041 ttcaaccttt ccgtgaggat gttggtatag aggcgttgcg ggagtttcgt attattatcc
    11101 gtcgcagtat tcctcttgcg ccggagcagt tgacctcgtt tgccagcgag gataaaaacc
    11161 agcaccaatc acttgatgac attttgaata gtaaccctgc tctgcatgtg gatatggatg
    11221 aagaaagtgg tcaaagttac catttaaacc tgatgcagct gctggaaggg gatgacaaat
    11281 cctccttggt agtcagcgcg cttaaacgct gcgctagctt gtattacgag gacgagtgta
    11341 acgacactct aattctggac tactgggtta atgatgctac tcgacaggct tttcgcgaga
    11401 attttaatgg ttcggcactg gctctattcc aggcgttcca agtattgctg acactcaatt
    11461 tgtataaggt gagtgataat ctcaaaactg atctgtatcg ctcaacaagt cactatgtca
    11521 gtgaaacggt accaacgttg gcgtccgacg aacgaattat gcgcttcaag tttgtgcgtt
    11581 ttactaaaca aggagtggaa gagccaatga tgctcaagga actctcggac ggtgaacacc
    11641 aattgcttca tagcctaggt ctatgtttac tgtttagaga aaccaacagc ctgtttctgt
    11701 tagacgaacc ggagactcat ttcaacccac attggcgtgc cagttttatc actcggatgc
    11761 gccaatgttt atgtaacact gagaatgtgg agcaggaaat gttgatcact actcatacac
    11821 ctttccttat ctcagatagt aaacccgaaa aagtactggt tttttctaag gataaatata
    11881 gcggtgcggt cacaataagc atacctaaat acaacacact tggtgcatca atcaataaaa
    11941 ttactatgaa taccttcggc aaacgtgaaa ctatcggtgg ccatgcgcaa gcagtactgg
    12001 atgatttacg cagacgtttt aacgaaggca ttgaagacaa ggaaactctg atcacagaaa
    12061 ttgatgaaca attgggtgac tcggtggaaa aagtattact cctcaaggct atttttgata
    12121 gcgacaatcc aacgaatgac gaggtttagc actgatgctg ttttcatata tctatgtgcc
    12181 acacaaaatg gaaaagatgc aggcattcat tgattttatt ttttatgagg tatggtgcaa
    12241 agcgcgggta agagggcctt tttgtcttaa actgtttgaa gctaacgcag aattgtatga
    12301 agtgatggag gatttttctt cctcggatac acaaggtgct gttttctttt ataaccatgt
    12361 agagaaaatt tatggcttgt tttcgtcact gactgaggta caaatcgatc agtttaaaca
    12421 gtggtatcaa gggaataatg atctggaaaa aatatgtgct aatgaccctt caatacaagt
    12481 tgtccgttat tccgatattg ccattcacca caaagatata gcagaacaac ttgctgtttt
    12541 ctttaagggc ttatactcac agtcactgct tgatctcgct gtactgcgtg ccaagatcgg
    12601 tgatatacac gatcactatc aatcttttgc agcagtgaac aaggcgggta aatgtccttt
    12661 ttgtggtatt ggagatataa agggtgggaa ccatagcaag cgcgaggcct atgaccatta
    12721 tttgcccaaa gctttatatc catttaattc gataaatttc cataatcttg ctccggcctg
    12781 tcatgagtgc aatagcacat ataagttatc caaagatcct attcagagcg gcgctcttcg
    12841 tcgtaaggcc ttcaatccat ttgcctcagt ggatcatgta attcaattac agattactct
    12901 acaacatgca aatatcgatg cgcttgagcc tgctgatatt attatacagt tcggtcccga
    12961 tacgctggag gaggaactag aaacatggaa agacttgtac ggtatagaag aacgttataa
    13021 agccaaagtt tgtgcagaaa atgacggtaa atactggctt actcaggtgc tagatgagtg
    13081 gaaggaggag gggttgagtc ctaccgaatt catgagaaca ttagcacgtc aagcgaaaaa
    13141 gaagccttat gctgaatgca atttccttaa agaacctttt cttaaagctt gccatcgaat
    13201 aggtgttttt tgaggctcaa tacatatcaa gctatcaatt tgtttataac ttactgttat
    13261 aaaaaaacat caaacggtgg ctttgccctg ctcccgattg attaacatac accgatgtta
    13321 gtaacgtctt cattagtcac atgaggacat cataatgaag aagcgttttt ccgacgaaca
    13381 gatcatcagt atcctccgcg aagctgaatc tggagttttt gcccgggagc tttgccgcaa
    13441 gcacgctatc tctgatgctg cgtactacac ttggcgcaag aagtttgatg gcatggaaat
    13501 gcctgaggtg aaacgtctta agtcatttga agaagagaac gcccacctca aggagttgct
    13561 tgcagaagtc atgatggata aagaagcgtt gcaggtggcc ctgaaccgaa agttctgacg
    13621 acagaccaga agcgggaagc tgtggaagtc atgtgtgagg caacgggtct gtcgcaacgt
    13681 cacgccagta ggctggcagg tctctccctg tcaacataat acagggggaa tgtcagtttg
    13741 catgggcgca tactgataga ggggcactga gaataagaca gatcgccact acggcatatg
    13801 atgcccgcgg ttacggcgct gtggcctgtt tcactaaatc gctcactatg ggtggtagtg
    13861 aataaactgt acgcggcgct caataagggg acggcaggga ctcggtagtg attgatgccg
    13921 gaacgaggca ttttaagaac aaaacgcccc tggttagcag tatcacctcg tccggcagga
    13981 aagcatgcta acatcaacaa gaacctcctg ttaatgccat ttcccgactc attaccacca
    14041 atctaatttc accgctgcga agtaaggggc gttaagcccg gctatgcagg ggcaggtttt
    14101 ctctcccgtg cgcttttccg ttcttcatat ctgcttccgg ttaatcgttt cccaacacaa
    14161 cccgtcccgc aagggtaaaa ttgcacgcat actgcgccct tgcaggacag aacgatgccg
    14221 ggaaagcgaa ccgtcaggcg atacgaagac gaaaatcaca cactgacgga gaaaaaacca
    14281 tgacgatttc cctttatacc tcccggacaa gcgcccctaa caccgcagcg gcgaccagcg
    14341 tatcctcgct ggagcagtca ggctcctcaa aaacgaaatt ttctaaaacc agaacggata
    14401 tttatcagac cgttaccgac agcatcattg cagcgctgga agccggtgta aaaccgtggt
    14461 cctgcccgtg gctgcgtgta tccggcatgt ctggactgcc atccaattac gccactggca
    14521 cggcttacag cggaatgaat atcatgttgc tgtggtgcag cgcatctaaa cagggtttca
    14581 gcgattcccg ctggatgact tacaaacagg cacaggcagc aggtggacag gttcgcaagg
    14641 gtgaacatgg cacaacagcc attttctata cgaccctgga aaaggaaaac gacgccggag
    14701 aggttgaaca aattccgatg ctgaaaactt tcaccgtgtt taacgttcag caaatcgacg
    14761 gtttgcccct gacaactgaa acagtcagcc cggaagctac atttaacccg ttgccgcagg
    14821 ctgagaacct gttacggaag agtggcgcaa acatcatcga gaaaggacaa aacgcctttt
    14881 tcagcccatc aactgatgaa gtctggttac cggagcgcca tttgttttcg gatgcggcta
    14941 acttctacgc taccggtctg catgagctgg ttcactggag cgggggtaaa aaacgcctga
    15001 accgtgaaat gaaagggaag tttggcagtg cggattatgc agaggaagaa cttgtcgcgg
    15061 agctgggaag tgcctttctg atggctgatc ttggcattga gggagaggta caacatgaaa
    15121 gctatattgc ttcctggctg aaagcgctga aaaacgacaa gcgttatatt ttcaaagcgg
    15181 tcagcgccgc ctctaaagcg cattcttatc tgatggataa actctgagga cggagccaga
    15241 caaccgcaag ggaatgcggt tacatggttt ttaaccggca acgctgcagg gcgcagactg
    15301 aggcggaacg cagcatagcg agtaccgaac agtctgcgcc tcgcagtgga ataaaaatat
    15361 accgggctgg cggtattacc gccagcccgg tgagaccatc acgatggcct gagtaaaagc
    15421 ttacgtatag ctgtctaatg acaagcgctt taattcatca agggtataaa tgcgaaatac
    15481 ccgacggtgg cgttcttcca gcgggacgtg ctgatggttg atgatgacat gtctgatgct
    15541 gtcaaatagg agctcaagtg cccgtttttt ctgtgggtca ggaatgacat aaaaaacatg
    15601 aatccacagt ttgcgggtac gggccagcag gtggctggca ataatcgact ggtagcgggc
    15661 tcgggttttc aggcgacgct cggtttcaat ggcgatcacg gtgctgccag gcaagatgat
    15721 caacccgtcc gggcgatgtt ttacctgata ctggctgaga aaggtggccc ggtcgccgtt
    15781 aatccatccc gacgcgcctt tcttctccag aataagcctg gcggcctgat tatcaagatg
    15841 gtgttccagc gtccagccgg tgatttttga tggttcaaac cgaggaggaa agattttatc
    15901 atccggggtt aacaccaccg ccagcccgtc gctggtgatc ccccataatg aaatcttcat
    15961 tgttcgtgat tcaagcacat gcttctggat taaccccatt cgctctgttt ttgccagtag
    16021 cgaataaagc gacttatgat cccggaaacc aaataacagc atcagagttt taaaatcact
    16081 gtaagtttct tctttcagga agttcagcag ttgttttatt ttttcgttgt tacgcgtctg
    16141 gcgctcgtga aatgatgaaa tcagcataag cgctccttaa aaatccagcg gggacaggtg
    16201 ttcttcatca tcaggtttcg gctttaccgg tttgacttcg ctttcgtcga agaaaagagc
    16261 cgggtgtgtt gtcatcacat ccgacatggc gggtttatca tcctcgcaaa aatccagcat
    16321 gatcttcacg ggggctaccg ttgcggcaat atcaggggaa accgaaaaag tttttagctg
    16381 gcgctttctg acctttatcg gcgagatcag tgaagcagaa ggtagcgttt ttgtcgtaaa
    16441 gataaagctg acaaaatcgg gcaggttcag gatcatattg ctgtcaataa agaaacgttc
    16501 ggcctggcgg attgtgcgct cactgtcgat ggtctccgtg agcatattat ctgttttagc
    16561 cttacggagt tcgtcatcca ccagaatagt gcctgacatt ctcgctaccc attccgctgt
    16621 atccgggtcc ataacccggt aaaccagttt gaatttggca ttttcaacga ccgcaccgac
    16681 aacggcgtca cctttcaaat ctgccgggca gtcttttaaa tcggcaatgg actggtggtc
    16741 cataataata tgcacgcctt tatcacgcgc tgcccctaat ccctccagtg ctgacctgga
    16801 taaatggtat ttcagttcgg aaagataaac agcaatgggg cgggggacgt ctattactcg
    16861 atcgcgcttt tctgccagct ggtaaaggcg aaccagtagc atgcgctggg cggtaataat
    16921 tttgctgttt cgcatggagc cgacaacata acagcagccg ccctcatcaa atatgtgctt
    16981 aagcgaaaag ccttctggtg agttaatggc attgagtaat gccagttcct caatttttcc
    17041 gaaaaaggct ttgatctttt cggcaatact ctgaacgtaa tcaccgttat aaacatcccg
    17101 gattgttgtc gatggattat cgctgacaaa ttgtgcggct atacgggcgg cttttcggtc
    17161 atcaatgcga taaaaatcag attcctgccc tttttctgcc aggctgaaac ctgcaacaaa
    17221 caattcttcc agctcatcgg gcgtgatatc ttcaatcaga tttaactggt attgctgttt
    17281 tcgcaggtca attaaggcaa aaggcttgcc tgcatcctcg caggctttgc ggtaaagatg
    17341 cggtgcccat tcatcgtctt tggggtccat aacaaaaaca ccttcaccgg ccagaatact
    17401 ttgataaagt aatatgccgg cggctacccc tttaccggcc cctgtggtgc cgataatatc
    17461 cgcgtgttgt ttctgccagt cttttaacgg gagatacatt ggttcatttt ccctgcccat
    17521 gccggtaaaa atgcctttat tcaggtcgat ataatccagc gggttataat gcagtgtttc
    17581 cggcagcagg gactttacgg tgcggacatc ggtgcgcaat tcccgttcaa gggtggtctt
    17641 tttaacaagg cgtttcttta ttttatccag ttccggtgtg aatatccggc gaagcataat
    17701 atgaaaaata atcccggtta cagtgaaagc aatccgtact gaccacgcca gtaccgtatt
    17761 atcactggtg ggtctgatct tatacagcca ctgaaaggat ccgataacga ccggagccag
    17821 tgtgccggag agaaaacaca gcagggaaaa agcaataatc agctttttcc agagcggcgc
    17881 tttctgccgt tcatcgcttt tcattgatgc aaaaaacggc atcgtcagcc ccgctaataa
    17941 tgccagcacc agttgtttct gttgcacaaa agccagcacc gccagcatcc cgttcactat
    18001 cggggacagt gaagcggtaa gcttatttaa aatcatcatg cctccttcgt cagcgattcg
    18061 ccccatgaca tcgccccatc aattcgcccc acggtgtcgg gcgaaaagac ggggcgagcg
    18121 tatggggtaa agaaggtaac cgctgtgcgg ccatgtaccg gaaagcatgc ttccctgcac
    18181 gaaacggcgt gcgccagtac atgcgggctg gacgccctta ttgcctgtcg catgggggta
    18241 atgtcgcggc tggacgccac gccaaaaccc ccagggtcaa aggcggcaca ccgtcgcacg
    18301 ctacgcgcga ccaacccctt taagacgcgc gtttagccta ttttttcttc gcaagctcga
    18361 aaaaatggga acgctgcttt aaaggggttg gtcgcgccta atcggcatat tccccgccgg
    18421 ggcgggaaat atagcctggc tgcgacggtg tgcggggcaa gccccccaca aaaaccggca
    18481 cgtgggcgtg cctttttgct cgctggggcg gcaaaatttt tgcggctccc cccggcccgc
    18541 ttcaattcgc tggggcgaat gttcgcgggt ggacgtggat cctgaaaatt agcaatttct
    18601 ccgaaattga attttctgtc cacgttccac ttcattattt ttcgtcttaa caatttcttc
    18661 gaaattgaag ccaaaaataa tgaagcctta aaatcccgtc gcctgttagt ctctgtattg
    18721 tacaatacac ttttgttttg tgtgattaca tttgctcgcg gtatatttca gccctgcact
    18781 ccctttcagc ttccagtgct tcactgtagg acgcatcatc aattttcgta cctttactct
    18841 cggcatagcg tcttaatcta tttgcgtcag cttcattaag ttctgaaaga tgatcgcgca
    18901 aaagaccgat aaaacagctt tcgtatattt cgtaatacag cccacaacct ctgtgggctt
    18961 cttttgataa cgtgtcatat accatggcta cagatattct gtcctgattt tttgagtgta
    19021 tattcttaat gaataaatct tcgtttatca tttcgaacct ctcatatcaa aatggatatg
    19081 tcagttatcc tttcactctg ccaaattttg aaaggatttt acttattgat tcagggtctg
    19141 cggctttgca ctcccctaaa aattcttttc gcatatcgaa tgttttaccc ggattgaaac
    19201 gatggtgttt tttaaatgcg ttgattttaa aaaatgcgcg ttctgctgaa ctgcattcac
    19261 tcccaccact attacctgta gcttttccgt acatgcaaag aacaacttcg cacgggtcag
    19321 cggcaaagga ataaatcggc gttcctgcgg tcaggcataa tacagtcgcc gcgataacgg
    19381 tttttttcat gataaatcct tattagattg tgttgcttaa atggattagc gagagaaata
    19441 aatagtggtt tctctgcacg tcaggcaatt aaagacaggc tggtattcaa taacgccttt
    19501 tgcgccattc tggcgaagcc agtttttggc attaaagaaa tcagtgccgg attgtgcagt
    19561 gacgacaatt cgtgttgaat gggcgactgc gtaaaatact gctggagtcc atattgtatc
    19621 gtagaaactt tgtgcgctga ttgatgatgt ccatttaccg ttaactgtcg gggaagggac
    19681 tataacgtta ttgtcactcc attgcgataa actggtattt aatggggcag cggctttatc
    19741 ccactccaca ggaacgggag gcggcggcga tgaacatccg gtaactattg ctgccaacat
    19801 gatgacttta agtttcttta tcatgctttc atttcctcaa aatactggtt tcgatgaatt
    19861 ggacggaaat agatgtcatt catacggcga acatttccgt ctaaatcaat gctcacaatc
    19921 acgtccaggc tatccagaac cttacgtaac ataaatgtat aggggagctg ggcgcactgt
    19981 ggattttcat agcaacgggt aataaaccca tctatagctt ctttcgctga tcctgcatga
    20041 atggaggtca tactcccttc atggccggaa cctgttattt taaggaagtc ccaggcttcc
    20101 gcaccgcgaa cctctgttaa taaaatgcgg tcagggttca tacggtaatt ccagcgtaaa
    20161 aggctcgccg gggtaacgat agaacctttt tcatctgatg attctgacgg ataaaaaaga
    20221 tggacgtagt ttttatggat aaagaacgtg atttccgggt tgtcctcaat ggttgatatc
    20281 cgaagatgta caggaatata ccctatcaac attttcatat aggtggtttt cccggtgctt
    20341 gtttccccgg cgaccgcgag agttttaccg tactcgacgc atttctccat aaacagagga
    20401 atattttttg tattgtacaa tgcaattaat tcctcgtcgt gcgtctccgt tttttcctcg
    20461 cctgttaccc ggttataaaa tcccgcatcg atgtatgact gatgcgggat ttgtaccttc
    20521 gatggcttac ggatggtgat agacaccgta tcgcgctcac aggccggggg aacaatcacc
    20581 tggcaccgtt cgccagattc cagcgtggct gacagccccg gcttaatatc ttcgatattg
    20641 tcgccgtggt gctttgccag gcaccgggca aagttgtagc aatcctcata ggacaaagga
    20701 acggcgtgct gctcccatac gccgttgatt ttggtataca gctcacctgg acgattgacg
    20761 gcgatctccg tcaggccggg aagctctaga aagtcgccaa agaaacgctg tttatagcgg
    20821 tcgagggaaa tattcttagc ggtcattttt caacctcagt atatagatgt tggaaaaatc
    20881 aatatcctcg cctgtgatta ggttgatgat ctcgccctga ttcttataga gcgttggggg
    20941 aatattgatg ctgttctcta gcgtggtacg tgccatatct gccatagcct ggcggctgtt
    21001 ttccgtatag tccgtattgc ggtctttttt acccgcgctg ttggatgccc atgcgccaat
    21061 atcggggatc atgccgacca ttaacgcgcc gccgaaccgt tcccagaagt gcgaatctat
    21121 ccagccatca acgccagcct cgcccagctc gccagccgcg ctggtatcaa ccaacgggat
    21181 atcgagataa ggcggctggc gggtgcgtag cttcgtcgca atgatgaatg cccgcccttg
    21241 cccgtgcttc ataccttctt ccgctatggc gcggtaaagt aatgatgcgg tggtgccttt
    21301 ctctatcagc ttcgtgttgc cgctggcgct ccagatgtca gtagtgaccg tgcagcgaag
    21361 tttccccgcc cggtcagata caaagcggcg atccagtgag caggggatcg aggtattttc
    21421 cgggatgtac aggtcagggt tatagggtat gcggcgcagt ggtgcggggc tttgtcccgg
    21481 cggcggtgcg gcggtatttg tggccgcgct gctgtcctgt tgtccggtgg tcgttgccga
    21541 tgtcagcgtc atttcctgct gccgggtttt taccgggttc tgtgtggtgg ccgaaccatc
    21601 acggcgaata aggaagctgg ctttgttgag ttctggcggg gcggccggag ccacctgccc
    21661 tgttcccccc gtgctgctct ggccgttatc ctgttgctct ggctcttctt cggctgtatc
    21721 ggtggacata ccgagatcgt tacgctgccg gtaatcggtt ttgttcgtct gcggggctgt
    21781 gtcctgtttc ttttcttccg taggctgcca caggatattg cgataaaccc agttaccacc
    21841 ccatgccagg aagataagcg tgaccgcgac aatggcaaga aaggcggttg ctttgccccg
    21901 tttgcgcttt ttcagcttgt taacggcggg ttgtaccggg tctttctctt cgtcgtcctg
    21961 cgcattgaga agctcggcct cccttttagc gcgggcttcc cgctcaagcg tggcaatatc
    22021 atcctcagcg tgtgccggga atgcctgcgc ttcatccggc acaggcattt tgttttcgtc
    22081 gttcatatgc acgtttcctt ttataaaaat atttttatag gttaattgga ttccggtttt
    22141 tccactcttt ccacctgccg ggatacggtg gaaccatcgg cggcgtgtac cttgccaaat
    22201 ccgctatttt ccagacccac aacggcatta ccggaacgca gtactaggcg tggcgtcacc
    22261 tcctgaatca ccagtacggt gaaatcgcct ttcttctgga tactgctgtt aaccacatgc
    22321 tctttgccgt tcagctcttt ggtgacggaa ggaatggact tagacgggga gaagcccacg
    22381 aacgtaaagc ggccatcgtc gtaagcaaaa tcgggaacaa tgttgaaact gcctttgccc
    22441 ggatatttgg tgtaactcca gttgcggggc gtctgcgccg agttcagcgc tttctggacg
    22501 ctggcctgtt gctgtttctg ctcccactcg cgctgtctgg ccgtcgcctc ccggctcgct
    22561 ttgtcccgtt cttcgcccgg atagcgatag ctcacctgga aagcgggttg ttgtgccgat
    22621 ttatcatcga tgacgttcag ctcgacgttg tacaggcgct tactggtgac aaccagcata
    22681 ttggtatgcc agtcccggct gttcgggggg atcacgacct gcgttgtgtt gccatcttct
    22741 ccgggcgctc cctgcgtgag cgcgaccggg cgaacgttga cccggtttgc atccggcgtg
    22801 gcttcccacg cctcatcaaa gccaggtttg gcgcttatga ccgcctcatc gttatcaaag
    22861 actagcgttg tcataaagcc gggtttggtg ttaacgacag tgacgttctg cgggttatag
    22921 ataacctgct gcacgcggga gtcatagcgg cttgcctgcg gtatggccgc agcccatgcc
    22981 gcgccgcaca tcatcagtgc cagtgcggta aacgttaact ttttcatcat tcacctcccc
    23041 ggatttcgcg gtcggtctgc caactggtga cggtaaagcc gaagtagttg atctcgcgtt
    23101 ccgcatcgct catttccttg tcagggttag aatggaacgt gaaccgggca tcccaatatt
    23161 cgttgcgggt gctgttatca gccagacggc ggataatctt cttgtagcgg atggtggcga
    23221 ccctatcagg ggctgtcgca tcggtgatct ggttggacaa gatctccact ttcacggtgt
    23281 gcgccccgtt cttataaacc ttgtctgggg cgttttttcc ggcgtaaagc gccagatagt
    23341 catcgtttac ctggggagcg ttgtagacct gtaccgtctc gtagtcgtcc tgcaaagagg
    23401 gatagacata ccgctcacgc actttgacgt agtttgcggc catcgccttt tgataggctt
    23461 ctgttgcggt caggctggtt ttcgatgtcc gggtaacgtg ttccacccgt cctgtgtggt
    23521 tatccaaggt atacagctca acgtccgtct gtttcagcgg caacatcacg accacggcga
    23581 cgagcgccag taccgcaatc agcagaccca taccgccaac aacaaaaccg gcttttgtgg
    23641 cgcgtttatc ccgctcaatc atttgctgct caaaagtgcg ggattcagct attaatttct
    23701 gttcactcat gactgtttaa ctccgccata atttgagggg tgtttacggg ttctccctta
    23761 ccgctaaagg cagagggagg cgtgttctgg gcgcagccag aaagcgcgca cagcaaagcc
    23821 agcgcaatca agcgtttcat caatgatttc ctcaactaaa ttagatatat gaaaatataa
    23881 ttatattttc atatgatgat atttcggggg gatggacggg agacgtctgg cctagctgtt
    23941 gaacttctta accgcggatt ctctcgactg tgccagcctc cgcgcttcgt tccgggctat
    24001 catctgctca atcgcgtact tccgcgcttt agatgcgtta tagcctaact cacctccggg
    24061 cttgccgggc ttacctgcat tcgcatcctt ccagccctga atgttgtcct gggcggaacg
    24121 tttggtttct ttaactgcac ccccggctag cttcccggca ccaaaagcag ccgcaccgat
    24181 acctacagcg gccagcccct gcatggatac ggtagcgctt gccccggcca gagctgcggc
    24241 taccttagcg gaaatataca ccagtattgc agcgaaaata cctgcaa
//
LOCUS       DAPGUL010000068        24183 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.068, whole genome shotgun sequence.
ACCESSION   DAPGUL010000068 DAPGUL010000000
VERSION     DAPGUL010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24183
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.068"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..906)
                     /locus_tag="RHX21_002880"
     CDS             complement(<1..906)
                     /locus_tag="RHX21_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418699.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1988037.1"
                     /translation="MATAWYKQVNPPQRKALFSAWLGYVFDGFDFMMIFYILHIIKAD
                     LGITDIQATLIGTVAFIARPIGGGFFGAMADKYGRKPMMMWAIFIYSVGTGLSGIATN
                     LYMLAVCRFIVGLGMSGEYACASTYAVESWPKNLQSKASAFLVSGFSVGNIIAAQIIP
                     QFAEVYGWRNSFFIGLLPVLLVLWIRKSAPESQEWIEDKYKDKSTFLSVFRKPHLSIS
                     MIVFLVCFCLFGANWPINGLLPSYLADNGVNTVVISTLMTIAGLGTLTGTIFFGFVGD
                     KIGVKKAFVVGLITSFIFLCPLFFIS"
     gene            1515..2861
                     /locus_tag="RHX21_002881"
     CDS             1515..2861
                     /locus_tag="RHX21_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4-like element IS4 family transposase"
                     /protein_id="HDV1988038.1"
                     /translation="MFPDFFMHIGQALDLVSRYDSLRNPLTSLGDYLDPELISRCLAE
                     SGTVTLRKRRLPLEMMVWCIVGMALERKEPLHQIVNRLDIMLPGNRPFVAPSAVIQAR
                     QRLGSEAVRRVFTKTAQLWHNATPHPHWCGLTLLAIDGVFWRTPDTPENDAAFPRQTH
                     AGNPALYPQVKMVCQMELTSHLLTAAAFGTMKNSENELAEQLIEQTGDNTLTLMDKGY
                     YSLGLLNAWSLAGEHRHWMIPLRKGAQYEEIRKLGKGDHLVKLKTSPQARKKWPGLGN
                     EVTARLLTVTRKGKVCHLLTSMTDAMRFPGGEMGDLYSHRWEIELGYREIKQTMQRSR
                     LTLRSKKPELVEQELWGVLLAYNLVRYQMIKMAEHLKGYWPNQLSFSESCGMVMRMLM
                     TLQGASPGRIPELMRDLASMGQLVKLPTRRERAFPRVVKERPWKYPTAPKKSQSVA"
     gene            complement(3375..3604)
                     /locus_tag="RHX21_002882"
                     /pseudo
     CDS             complement(3375..3604)
                     /locus_tag="RHX21_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546148.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
     gene            4191..5371
                     /locus_tag="RHX21_002883"
                     /pseudo
     CDS             4191..5371
                     /locus_tag="RHX21_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001535067.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
     gene            complement(5688..6953)
                     /locus_tag="RHX21_002884"
                     /pseudo
     CDS             complement(5688..6953)
                     /locus_tag="RHX21_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001642584.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
     gene            complement(7139..7223)
                     /locus_tag="RHX21_002885"
     tRNA            complement(7139..7223)
                     /locus_tag="RHX21_002885"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7187..7189),aa:Leu,seq:caa)
     gene            7419..8438
                     /gene="ahr"
                     /locus_tag="RHX21_002886"
     CDS             7419..8438
                     /gene="ahr"
                     /locus_tag="RHX21_002886"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418690.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent aldehyde reductase Ahr"
                     /protein_id="HDV1988039.1"
                     /translation="MSMIKSYAAKEAGGELEVYEYDPGELRPQDVEVQVDYCGICHSD
                     LSMIDNEWGFSQYPLVAGHEVIGRVVALGSAAQDKGLQVGQRVGIGWTARSCGHCDAC
                     ISGNQINCEQGAVPTIMNRGGFAEKLRADWQWVIPLPENIDIESAGPLLCGGITVFKP
                     LLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVN
                     SRDPQALKALAGQFDLIINTVNVSLDWQPYFEALTYGGNFHTVGAVLTPLSVPAFTLI
                     AGDRSVSGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDAIQHVRDGKARYRVV
                     LKADY"
     gene            complement(8442..9005)
                     /gene="idnK"
                     /locus_tag="RHX21_002887"
     CDS             complement(8442..9005)
                     /gene="idnK"
                     /locus_tag="RHX21_002887"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HDV1988040.1"
                     /translation="MAGESFILMGVSGSGKTLIGSKVAALLSAKFIDGDDLHPAKNID
                     KMSQGIPLSDEDRLPWLERLNDASYSLYKKNETGFIVCSSLKKQYRDILRKGSPHVHF
                     LWLDGDYETILARMQRRAGHFMPVALLKSQFEALERPQADEQDIVRIDINHDIANVTE
                     QCRQAVLAIRQNRICAKEGSASDQRCE"
     gene            9222..10253
                     /gene="idnD"
                     /locus_tag="RHX21_002888"
     CDS             9222..10253
                     /gene="idnD"
                     /locus_tag="RHX21_002888"
                     /EC_number="1.1.1.264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-idonate 5-dehydrogenase"
                     /protein_id="HDV1988041.1"
                     /translation="MQVKTQSCVVAGKKTVAVTEQTIDWNNNGTLVQITRGGICGSDL
                     HYYQEGKVGNFMIKAPMVLGHEVIGKVIHSDSSELHEGQTVAINPSKPCGHCKYCIEH
                     NENQCTDMRFFGSAMYFPHVDGGFTRYKMVETSQCVPYPAKADEKVMAFAEPLAVAIH
                     AAHQAGELQGKRVFISGVGPIGCLIVSAVKTLGAAEIVCADVSPRSLSLGKEMGADVL
                     VNPQNDDMDHWKAEKGYFDVSFEVSGHPSSVNTCLEVTRARGVMVQVGMGGAMAEFPM
                     MTLIGKEISLRGSFRFTSEFNTAVSWLANGVINPLPLLSAEYPFTDLEEALRFAGDKT
                     QAAKVQLVF"
     gene            10277..11041
                     /gene="idnO"
                     /locus_tag="RHX21_002889"
     CDS             10277..11041
                     /gene="idnO"
                     /locus_tag="RHX21_002889"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HDV1988042.1"
                     /translation="MNDLFSLAGKNILITGSAQGIGFLLATGLGKYGAQIIINDITAE
                     RAELAVEKLHQEGIQAVAAPFNVTHKHEIDAAVEHIEKDIGPIDVLVNNAGIQRRHPF
                     TEFPEQEWNDVIAVNQTAVFLVSQAVTRHMVERKAGKVINICSMQSELGRDTITPYAA
                     SKGAVKMLTRGMCVELARHNIQVNGIAPGYFKTEMTKALVEDEAFTAWLCKRTPAARW
                     GDPQELIGAAVFLSSKASDFVNGHLLFVDGGMLVAV"
     gene            11104..12423
                     /gene="idnT"
                     /locus_tag="RHX21_002890"
     CDS             11104..12423
                     /gene="idnT"
                     /locus_tag="RHX21_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gnt-II system L-idonate transporter"
                     /protein_id="HDV1988043.1"
                     /translation="MPLIIIAAGVALLLILMIVFKVNGFIALVLVAAVVGFAEGMDAQ
                     AVLHSIQNGIGSTLGGLAMILGFGAMLGKLISDTGAAQRIATTLIATFGKKRVQWALV
                     ITGLVVGLAMFFEVGFVLLLPLVFTIVASSGLPLLYVGVPMVAALSVTHCFLPPHPGP
                     TAIATIFEANLGTTLLYGFIITIPTVIVAGPLFSKLLTRFEKAPPEGLFNPHLFSEEE
                     MPSFWNSIFAAVIPVILMAIAAVCEITLPKTNTVRLFFEFVGNPAVALFIAIVIAIFT
                     LGRRNGRTIEQIMDIIGDSIGAIAMIVFIIAGGGAFKQVLVDSGVGHYISHLMTGTTL
                     SPLLMCWTVAALLRIALGSATVAAITTAGVVLPIINVTHADPALMVLATGAGSVIASH
                     VNDPGFWLFKGYFNLTVGETLRTWTVMETLISIMGLLGVLAINAVLH"
     gene            12490..13488
                     /gene="idnR"
                     /locus_tag="RHX21_002891"
                     /gene_synonym="gntH"
                     /gene_synonym="yjgS"
     CDS             12490..13488
                     /gene="idnR"
                     /locus_tag="RHX21_002891"
                     /gene_synonym="gntH"
                     /gene_synonym="yjgS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator IdnR"
                     /protein_id="HDV1988044.1"
                     /translation="MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVAKETGERIAKIM
                     EEINYIPNRAPGMLLNAQSYTLGILIPSFQNQLFADILAGIESVTSEHNYQTLIANYN
                     YDRDSEEESVINLLSYNIDGIILSEKYHTIRTVKFLRSATIPVVELMDVQGERLDMEV
                     GFDNRQAAFDMVCTMLEKRVRHKILYLGSKDDTRDEQRYQGYCDAMMLHNLSPLRMNP
                     RAISSIHLGMQLMRDALSANPDLDGVFCTNDDIAMGALLLCRERNLAVPEQISIAGFH
                     GLEIGRQMIPSLASVITPRFDIGRMAAQMLLSKIKNNDHNHNTVDLGYQIYHGNTL"
     gene            13566..15068
                     /locus_tag="RHX21_002892"
     CDS             13566..15068
                     /locus_tag="RHX21_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF853 domain-containing protein"
                     /protein_id="HDV1988045.1"
                     /translation="MSEPLLIARTPDTELFLLPGMANRHGLITGATGTGKTVTLQKLA
                     ESLSEIGVPVFMADVKGDLTGVAQAGTVSEKLLARLKNIGVNDWQPHANPVVVWDIFG
                     EKGHPVRATVSDLGPLLLARLLNLNDVQSGVLNIIFRIADDQGLLLLDFKDLRAITQY
                     IGDNAKSFQNQYGNISSASVGAIQRGLLSLEQQGAAHFFGEPMLDIKDWMRTDANGKG
                     VINILSAEKLYQMPKLYAASLLWMLSELYEQLPEAGDLEKPKLVFFFDEAHLLFNDAP
                     QVLLDKIEQVIRLIRSKGVGVWFVSQNPSDIPDNVLGQLGNRVQHALRAFTPKDQKAV
                     KAAAQTMRANPAFDTEKAIQELGTGEALISFLDAKGSPSVVERAMVIAPCSRMGPVTE
                     DERNGLINHSPVYGKYEDEVDRESAYEMLQKGFQASTEQQNNPPAKGKEVAVDDGILG
                     GLKDILFGTTGPRGGKKDGVVQTMAKSAARQVTNQIVRGMLGSLLGGRRR"
     gene            complement(15229..16311)
                     /gene="lptG"
                     /locus_tag="RHX21_002893"
     CDS             complement(15229..16311)
                     /gene="lptG"
                     /locus_tag="RHX21_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313266.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptG"
                     /protein_id="HDV1988046.1"
                     /translation="MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQ
                     GSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQV
                     ALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNF
                     VYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPK
                     QITGSQTVSGTWKTNLTPDKLGVVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMW
                     SKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYG
                     IPPIIGALLPSASFFLISLWLLMRKS"
     gene            complement(16311..17411)
                     /gene="lptF"
                     /locus_tag="RHX21_002894"
     CDS             complement(16311..17411)
                     /gene="lptF"
                     /locus_tag="RHX21_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptF"
                     /protein_id="HDV1988047.1"
                     /translation="MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIP
                     ANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAA
                     MILAVFTAIVAAVNVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLF
                     IESVDGSDFKDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNQGTRFEGTAL
                     LRDFRITDFQDYQAIIGHQAVALDPNDTDQMDMRTLWNTDTDRARAELNWRITLVFTV
                     FMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNGGKGKLDPTLWMWTV
                     NLIYLALAIVLNLWDTVPVRRLRASFSRKGAV"
     gene            17678..19189
                     /gene="pepA"
                     /locus_tag="RHX21_002895"
     CDS             17678..19189
                     /gene="pepA"
                     /locus_tag="RHX21_002895"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HDV1988048.1"
                     /translation="MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYIS
                     ALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLND
                     TGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFN
                     VPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNV
                     ITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDS
                     GGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRP
                     GDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHI
                     TGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITA
                     GCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE"
     gene            19543..19986
                     /gene="holC"
                     /locus_tag="RHX21_002896"
     CDS             19543..19986
                     /gene="holC"
                     /locus_tag="RHX21_002896"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004098129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit chi"
                     /protein_id="HDV1988049.1"
                     /translation="MKNATFYLLDNDTTIDGLSAVEQLVCEIAAERWRSGKRVLIACE
                     DEKQAYRLDEALWARPAESFVPHNLAGEGPRGGAPVEIAWPQKRSSSPRDILISLRTS
                     FADFATAFTEVVDFVPYEDSLKQLARERYKAYRVAGFNLNTATWK"
     gene            19986..22841
                     /gene="valS"
                     /locus_tag="RHX21_002897"
     CDS             19986..22841
                     /gene="valS"
                     /locus_tag="RHX21_002897"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HDV1988050.1"
                     /translation="MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNV
                     TGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTR
                     HDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRL
                     YKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLV
                     VATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCV
                     KITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQK
                     LERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKP
                     AVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRN
                     EEEVRKENNLGADVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSG
                     FDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPL
                     DMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALAST
                     GRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFN
                     QTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLV
                     TVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTE
                     WLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVL
                     PADDKGPVSVAKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEG
                     FVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL"
     gene            complement(22897..24093)
                     /locus_tag="RHX21_002898"
     CDS             complement(22897..24093)
                     /locus_tag="RHX21_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF898 domain-containing protein"
                     /protein_id="HDV1988051.1"
                     /translation="MAQVINEMDVPSHSFVFHGTGERYFLICVVNVLLTIITLGIYLP
                     WALMKCKRYLYANMEVNGQRFSYGITGGNVFFSCLVFVFFYFAILMTVSADMPLVGCV
                     LTLSLLVLLIFMAAKGLRYQALMTSLNGVRFSFNCSMKGFWWVTFFLPILMAIGMGTV
                     FFISTKMLHANSSSSVIISVVLMAIVGIVSIGIFNGTLYSLVMSFLWSNTSFGIHRFK
                     VKLDTTYCIKYAILAFLALLPFLAVAGYIIFDQILNAYDSSVYANDDIENLQQFMEMQ
                     RKMIIAQLIYYFGIAVSTSYLTVSLRNHFMSNLSLNDGRIRFRSTLTYHGMLYRMCAL
                     VVISGITGGLAYPLLKIWMIDWQAKNTYLLGDLDDLPLINKEEQPDKGFLASISRGIM
                     PSLPFL"
BASE COUNT         6329 a         5953 c         6010 g         5891 t
ORIGIN      
        1 agaaataaaa aaaagaggac aaaggaaaat aaatgaagtt attagaccga ctacaaaggc
       61 tttttttaca ccaatcttat caccaacaaa accaaaaaat attgtacctg tcagtgttcc
      121 taaacctgct attgtcatca gagttgaaat gaccactgta ttaactccat tatctgccag
      181 gtaggaagga agtagtccgt ttatcggcca gtttgcacca aatagacaaa aacagacgag
      241 gaaaacgatc atagagattg aaagatgtgg ttttctgaag acagacaaaa atgttgattt
      301 atccttatat ttatcttcaa tccactcctg actttctgga gcactttttc tgatccaaag
      361 aactagtaaa actggtaaca ggcctataaa aaaagagttt ctccatccat atacttcagc
      421 aaactgaggg attatttgtg ccgcaataat atttccaaca gaaaaaccac ttaccaaaaa
      481 agcactagct ttagattgaa gatttttagg ccaactttct accgcataag ttgaagcaca
      541 tgcatattca ccagacatcc ctaagccaac aataaaacgg caaactgcga gcatatataa
      601 gtttgtagca ataccgctaa ggcctgttcc gactgagtaa atgaaaattg cccacatcat
      661 cattggctta cgaccatatt tatcagccat ggcaccaaaa aaaccacctc caataggtct
      721 ggctatgaag gccactgtcc ctattaaagt agcctgaata tccgtaatgc caagatctgc
      781 ttttataata tgaagaatgt aaaatatcat cataaaatca aagccatcaa atacatatcc
      841 aagccatgcg gaaaaaagag ctttccgttg tggtggatta acttgtttat accatgctgt
      901 tgccatattt gtttcctgtg ttattctaat atagccctta aagtaaatat tagggagcct
      961 caacaatatc cagaaataat tatattgtct tcaaatacgc cagtactatt gattgttatc
     1021 aatacctaat cagtacaatc ttttcctcca tttcttctta acatatttca ctctatgaaa
     1081 gataaaactg atacccacct acagttttgg gtcaccaaca aaaaacaatg ttcgccagat
     1141 attccaccac tggcacagtt caaccctgct tcaaaaattg acttattcat tgtgctcatt
     1201 ttcgtagtcc gttcaggttg aataaaactc ccttcgtcaa atgaggaaag actgagaggt
     1261 tattacttta gcttacgtta tagctgtttt cctttgcagt atttctttgc ttttctgtat
     1321 acctttatac ctgttatacc agatcaaaaa acaagcaatc cacataacaa aacgcgtttt
     1381 gttactgatg tcacaaattg agcatatttt tgtagctgat agtttgttac aaacaccaga
     1441 accaagatta atgccgatca gttaaggatc agttgaccga tccagtggct gtgtaagaat
     1501 ccggaaacgc tcacttgttt ccggattttt ttatgcacat tggacaggct cttgatctgg
     1561 tatcccgtta cgattctctg cgtaacccac tgacttctct gggggattac ctcgaccccg
     1621 aactcatctc tcgttgcctt gccgaatcag gtactgtaac gctacgcaag cgccgtcttc
     1681 ccctcgaaat gatggtctgg tgtattgttg gcatggcgct tgagcgtaaa gaacctcttc
     1741 accagattgt gaatcgcctg gacatcatgc tgccgggcaa tcgccccttc gttgccccca
     1801 gtgccgttat tcaggcccgc cagcgcctgg gaagtgaggc tgtccgccgc gtgttcacga
     1861 aaacagcgca gctctggcat aacgccacgc cgcatccgca ctggtgcggc ctgaccctgc
     1921 tggccatcga tggtgtgttc tggcgcacac cggatacacc agagaacgat gcagccttcc
     1981 cccgccagac acatgccggg aacccggcgc tctacccgca ggtcaaaatg gtctgccaga
     2041 tggaactgac cagccatctg ctgacggctg cagccttcgg cacgatgaag aacagcgaaa
     2101 atgagcttgc tgagcaactt atagaacaaa ccggcgataa cactctgacg ttaatggata
     2161 aaggttatta ctcactggga ctgttaaatg cctggagcct ggcgggagaa caccgccact
     2221 ggatgatacc tctcagaaag ggagcgcaat atgaagagat cagaaaactg ggtaaaggcg
     2281 atcatctggt gaagctgaaa accagcccgc aggcacgaaa aaagtggccg ggactgggaa
     2341 atgaagtgac tgcccgcctg ctgaccgtga cgcgcaaagg aaaagtctgc catctgctga
     2401 cgtcgatgac ggacgccatg cgcttccccg gaggagaaat gggggatctg tacagtcatc
     2461 gctgggaaat cgaactggga tacagggaga taaaacagac gatgcaacgg agcaggctga
     2521 cgctgagaag taaaaagccg gagcttgtgg agcaagagct gtggggtgtc ttactggctt
     2581 ataatctggt gagatatcag atgattaaaa tggcggaaca tctgaaaggt tactggccga
     2641 atcaactgag tttctcagaa tcatgcggaa tggtgatgag aatgctgatg acattgcagg
     2701 gcgcttcacc gggacgtata ccggagctga tgcgcgatct tgcaagtatg ggacaacttg
     2761 tgaaattacc gacaagaagg gaaagggcct tcccgagagt ggtaaaggag aggccctgga
     2821 aataccccac agccccgaaa aagagccagt cagttgctta actgactggc attacagaac
     2881 caagatgcct atttcgtttc agcatcaact gttaaattat ctggttgcca acgagaatac
     2941 tgagcttttt tgtccccaag actgaccgtc aacgccacaa tctttgactg tttgacattg
     3001 tcatgcccgc aggccagcgg atctaaagac attagactgc ttgcatcagc cagttgcgta
     3061 tctggctatg tcccttaatt ggtaagggtt cgaggaactc aacattaacg cattttttag
     3121 cgcatcaccg acagtgtata tgaacgattg cactctgacg atggttgatt tatttggttg
     3181 cgtaggggct agctagtctg gtaccggagg ctagatctga agtactgacc ccaggaataa
     3241 cgccgggcta actcatattc tgacccattg tcagcccgcg tgtttactgc tctagctcat
     3301 ttcctgttgt caggcgttca attcccaact gcaggttatg gcccggtgca caaacacctg
     3361 acggcaggta tcacttaccc gaagaaggta aagccctcaa gaggcagtaa ctcagccaac
     3421 ctctcctccg gccactccgg cagacgcgtc aggacgtccg tcagccaagc atgtggctcc
     3481 agactgcggt tcccagaagg ctcattatct gtgccgcgcg gttcccggcc accagtgaac
     3541 cagcgaacaa ccaggccttt cgtcccataa cgaccggacg gatagcacgc tcgcagatat
     3601 tgttgtgtgt gccttgaaat gcacgatctt tccgtcggtg aaagtccgcc ccggctaact
     3661 ctcgctccga ctggaaggac aagaagcggt ccaggaggta acaaaagggc tgaatctctc
     3721 cctgaaacga cttcttcagg aagtcaacgg gttatgcggg ccgtaacgtg agtgaacact
     3781 gagcagccat cgaaatgccg tcgagggtgc tgacacgcca caataacggg gaaggccgac
     3841 gatgaccggg aagagagtga gaaaggcatc ggtcataccc accggggttg tggtgtcagc
     3901 atgcataaca attgatcgat cgtgcaacaa gagaagtcca taacggtgtc tgtccgggtg
     3961 acgggcaaca acgcctcgcg agggggtgaa tcggttgtta tggatggcag atggggtgta
     4021 gtagtgaaaa tactgagtaa tgtcagagga gcgaaggccc cctcttgcag taccagtgta
     4081 acatgcagga agagcccggc gattgccatc agcctcacaa ccccgctaga accggttcag
     4141 aacctacaga aaacactaca ggagaaagca aagtgaaccg ccccgtgttt cctgtttatc
     4201 attttctggt cagtgccgcg attctggtat tcgtggtgat tttctggcgg acacaccatc
     4261 gcgaccaccg taactggctg gctctacggc tattcgtatt atgctctgta aaccgttggc
     4321 cattgcggat ggttaaagga acagttgtgg ggacaactga cacattacgt gaaatgcagc
     4381 gttatgaaca actgagtagc acggggctga caactggaaa atccagccgg gagcaccgtt
     4441 atatgatacg attgttattg tcactggtga gagtgtgcgc agggattata tgtcagtgta
     4501 tgactatccc gtaccaacca caccgtggct gaatacggca cccggtttat ttattgacga
     4561 ttatacctcg acagcctcca gtacagtgtc ttccctgagc cggacactga tttatgacta
     4621 tgagcagaac cctgattccg gcaacaatgt ggtggcgctg gcagcaaaag caggatacag
     4681 cacatggtgg atatccaatc aaggaaaact gggggagcat gacacacgca tctctgttat
     4741 tgcttctgat gcggagcatg ccactttcct caagaaaggc agcttcgctt cccgtaaaac
     4801 agatgacaaa ctgttgttac aggaaacaga acgtgcgctg gcggatacat cctctccgaa
     4861 gataattttc ctgcacatga tgggttctca tccaaatccg tgtgacagcc ttaactccta
     4921 gccgaataat tacctggagc agtatccccg aaaaattgcc tgttacctcg ccagcatcag
     4981 taaactggat aactttcttg gccagcttga tggtatcctt cgccggtact cacgtcattt
     5041 cgccatgctt tacttttctg gccttgggct gtcggtcagc gacagtgcca atcctgttca
     5101 tcattatggt catgtgcagg gaggctacag tgtgccactg attattaccg ccagtgacat
     5161 aacgtctcat cagcccgtca gtagaaaaat cagtgcccgt catttcgcag gtatttttca
     5221 gtggatgacc ggtatttgta ctgaaaatat accgccattc aatccgctga cagacgaaga
     5281 taactaacct gttatggttt ttaagggaga gaggaatata ccggcagaca gtttgaaacc
     5341 tcagccactt attcttcctg atcacaggta atcatatatg gcagactgta atacagtcgc
     5401 ttgtactgaa aagtattctg tataaaatat ccgtattcat atcagcacaa gggaccatca
     5461 aatccctgca gcactcctta cgtcagttat cccgcatcac cctgtgagta caggattttt
     5521 tatgaggtta cttttttatt gaatgtatat aaataatgaa taaccgcgga ttctgataat
     5581 cccccctgca gggagcggta aatagtaaat acatcagtta ataccgtttg tcttttttaa
     5641 caaagaaaat aatcctagaa taattcccgg gcatttgccc gggatgatta ctgttttaat
     5701 ggattattaa tctttgcata ttcaaatgga ctgataaacc tttctctgtt tacatccaga
     5761 aaatcggccc accactgtag catcaatcgc cgttcttcca gatgctctgc tttatggata
     5821 tacgcggccc tcactgaatt tcgcgccatg tggctcatct gacgttcaac agcatcacga
     5881 gaccacagac ctgattcgac caatgaacta caggccattg ttcgaaagcc atgaccacaa
     5941 acctctactt ttgtatcata ccccatgacc cgtaacgcac tatttaccgt attctcactc
     6001 atgggtttgt gcgaatcgtg atcaccaata aatatcaagt catgggcccc ataaaactgt
     6061 tttatctgct ttaaaattgc aagagcttgc gttgaaagag gcactagatg cgttgtacgc
     6121 atttttgagc ctctatggga atgtttcact ccaggaatag gctcccgctc cggtgggata
     6181 gtccatatag acgcttcgaa atcgatctct gaccaacgag caaaacgcag ctcactggac
     6241 cgaataaaga tcagcaaagt gagttctatc gcccatcggg ttagcggcct accagtatag
     6301 ctatctattt ttgtaagcaa ctcagggatg cgctttaatt caagcgcggg acgatgttgt
     6361 cgattacagg aagcaaccgc cccagccatc tcttgtgccg ggttataatc aattaaccca
     6421 ctttgcactg catagcgcat gatggctgta gtgcgctgct gaagacgagc ggccacttca
     6481 agacgtccag acatttctac ggccttaata ggtgctaata aatctcgagt ttttaactca
     6541 gcgatattac gttcaccaag cgctgcaaaa agattatctt caagactttt tagcacacga
     6601 tgggcgtgat cttcagacca ctttttattg gtgccatgcc actcaatcgc gacttcttta
     6661 aaggttcgtg ctttactctg ttcaacctta tcatttttct ttttgtctcc cggatcgacg
     6721 ccattcgcaa gcagcttacg cgtctcgtca cgacgtactc tggcatccgc tagtgtgatt
     6781 tcaggataaa ccccaagtgc cagcattttt tgctttccct cataacggta ctgcaaacgc
     6841 cagtacttag aaccatttgg atggacaagc agatgcatac cgccaccatc agtcagctaa
     6901 tattgcttat ccgttggctt ggctgctctg actttgatat ctgttaatgc catcgtattc
     6961 cctccctgtt ggtacaagca ttatcgaacc ggaaatacca tcatctgtac caacatatgt
     7021 tggtagatgt acgttgatat cggttgacct tgagagagtt aatatagcgg gaaagataga
     7081 taaacactgg atttcaggca taaaaaaaga cctcagttga ggtctattta catacttttg
     7141 gtgccgaagg ccggactcga accggcacgt atttctacgg ttgattttga atcaactgcg
     7201 tctaccgatt tcgccacttc ggcactgaag aggtatgcgg aaaacgttgt ggattatacc
     7261 tgtcgcacgc caccatgcaa gcgccagctt gctcgcacct cgctaagtgc tgaaattttc
     7321 agcattgcat acagcgatgt gtaacctttg tcacactcca ggcaccccgc cctgccatgc
     7381 tctacacttc ccaaacaaca ccagagaagg accaaaaaat gtcgatgata aaaagctatg
     7441 ccgcaaaaga agcgggcgga gaactggaag tttatgagta cgatcccggt gagctgaggc
     7501 cacaagatgt tgaagtgcag gtggattact gcgggatctg ccattccgat ctgtcgatga
     7561 tcgataacga atggggattt tcacaatatc cgctggttgc cgggcatgag gtgattgggc
     7621 gcgtggtggc actcgggagc gccgcgcagg ataaaggttt gcaggtcggt cagcgtgtcg
     7681 ggattggctg gacggcgcgt agctgtggtc actgcgacgc ctgtattagc ggtaatcaga
     7741 tcaactgcga gcaaggtgcg gtgccgacga ttatgaatcg cggtggcttt gccgagaagt
     7801 tgcgtgcgga ctggcaatgg gtgattccac tgccagaaaa tattgatatc gagtccgccg
     7861 ggccgctgtt gtgcggcggt atcacggtct ttaaaccact gttgatgcac catatcactg
     7921 ctaccagccg cgttggggta attggtattg gcgggctggg gcatatcgct ataaaacttc
     7981 tgcacgcaat gggatgcgag gtgacagcct ttagttctaa tccggcgaaa gagcaggaag
     8041 tgctggcgat gggtgccgat aaagtggtga atagccgcga tccgcaggca ctgaaagcac
     8101 tggcggggca gtttgatctc attatcaaca ccgtcaacgt cagcctcgac tggcagccct
     8161 attttgaggc gctgacctat ggcggtaatt tccatacggt cggtgcggtt ctcacgccgc
     8221 tgtctgttcc ggcctttacg ttaattgcgg gcgatcgcag cgtctctggt tctgctaccg
     8281 gcacgcctta tgagctgcgt aagctgatgc gttttgccgc ccgcagcaag gttgcgccga
     8341 ccaccgaact gttcccgatg tcgaaaatta acgacgccat ccagcatgtg cgcgacggta
     8401 aggcgcgtta ccgcgtggtg ttgaaagccg attattgaaa atcattcgca gcgctgatct
     8461 gaggcgctgc cctctttcgc acatattctg ttttgtcgta tcgccagcac agcctgccga
     8521 cattgttcgg tgacattggc aatatcatgg ttgatatcaa tgcgcacaat atcctgttca
     8581 tctgcttgtg gacgctccag tgcctcaaac tgacttttta gtaacgctac cggcataaaa
     8641 tgcccagccc gacgctgcat tcgcgcgaga atagtttcat agtcgccatc taaccagagg
     8701 aaatgaacat gggggctacc cttgcgtaaa atatcacgat actgtttttt taatgatgaa
     8761 cagacaataa atcctgtttc attcttttta taaagactgt atgaagcatc atttaagcgt
     8821 tccagccagg gaagtcgatc ttcatcagat aatggaatac cctgcgacat tttatctata
     8881 tttttggctg gatgaagatc gtcaccatca ataaatttag cagataataa cgcggcaacc
     8941 ttgctaccaa ttaatgtttt accactccct gaaacgccca tcaaaataaa gctttcaccc
     9001 gccatttaaa atctcctgaa tcatcttacc tgctgcgata ctacgcctgg cggcataata
     9061 atttcacgtt tttttatttc tactgataag aattacaagg cacatcacgt tatgcgtaac
     9121 atagtaatgt aacaattttc tgacgtgatc ttcatcacaa ataatgacag ttaaaaccgc
     9181 ttaaatgctt ccgaggtgtc tacctgacca gtgaggaatt tatgcaagtg aaaacacagt
     9241 cctgcgttgt tgcgggcaag aaaactgttg ccgttaccga gcagacgata gattggaata
     9301 ataatggaac attagtacaa ataacccgag gtggaatttg cggttccgat ttacattatt
     9361 atcaggaagg aaaagtaggt aatttcatga taaaggcacc gatggtgtta ggtcatgaag
     9421 ttatcggtaa agttattcat agcgactcat cagaattaca tgaagggcaa acggtagcca
     9481 ttaatccgtc taaaccgtgc ggtcactgca aatactgcat tgaacataac gagaatcagt
     9541 gtacagatat gcgttttttt ggcagtgcca tgtatttccc tcatgttgat ggtggtttta
     9601 cccgttataa aatggtcgaa acgtcgcaat gtgtccctta tccggccaaa gctgacgaaa
     9661 aggttatggc ttttgccgaa cctttagccg tcgcgattca tgccgcacat caggccggcg
     9721 agttacaggg caagcgagta tttatttccg gtgttggacc cattggctgc ctgattgtca
     9781 gtgcagtgaa aacactgggg gccgcggaaa ttgtctgtgc tgatgtgagt ccccgttccc
     9841 tttcgctggg caaagagatg ggggcggatg tgctcgtaaa cccacaaaac gacgacatgg
     9901 atcactggaa agcggaaaaa ggctatttcg atgtcagctt tgaagtgtcc ggtcatcctt
     9961 catcagtgaa tacctgtctg gaggtcactc gtgcacgcgg cgtaatggtg caggtaggta
    10021 tgggaggcgc gatggcagaa ttcccaatga tgacgttgat tggtaaggag atttcactca
    10081 gaggctcttt ccgttttacc agcgaattta ataccgcagt gtcatggctg gcgaatggcg
    10141 ttatcaatcc actgccttta ctgagtgctg aatatccctt cactgacctg gaagaggcgc
    10201 tacgtttcgc cggtgataaa acccaggcag caaaagtcca gcttgttttc taagagataa
    10261 ataaaggaat aatacaatga acgatctatt ttcactggca ggaaaaaata tcttgattac
    10321 cggttcagca cagggcattg gctttttact ggcaaccggc ctgggtaaat atggcgcaca
    10381 aataattatt aatgatatta ctgccgaacg cgcagaactt gctgtagaaa aactccacca
    10441 ggagggtatt caggccgttg ccgcaccttt taatgttact cataaacatg aaattgatgc
    10501 cgccgttgaa catatcgaaa aggacatcgg ccccattgat gtgctggtga ataacgccgg
    10561 tatccagcgc cgtcatcctt ttactgagtt ccctgaacaa gagtggaatg atgtgatcgc
    10621 agtaaaccag accgccgtgt tcctggtatc gcaagcggta actcgtcaca tggttgaacg
    10681 caaggcaggt aaagttatta atatttgctc gatgcaaagc gaactgggac gtgacaccat
    10741 caccccttat gccgcatcga aaggggcggt aaaaatgctc acccgcggca tgtgcgtcga
    10801 gctggcgcgc cacaatattc aggtcaacgg tattgcgccg ggctatttca aaacagaaat
    10861 gactaaagca ctggttgagg acgaagcctt caccgcctgg ttgtgcaaac ggacccccgc
    10921 cgcacgctgg ggagatccgc aggaactgat tggtgctgcg gtgttccttt cttcaaaagc
    10981 ctctgatttc gtaaacggcc acctgttgtt tgttgatggc ggcatgttag tggctgttta
    11041 acagcccccc ctacgtgcag cgcgaaagcg ctgcttttct ggcactaata agagataaag
    11101 actatgccat taatcattat tgcggcaggc gtcgcgctgc ttcttatcct gatgatcgtc
    11161 tttaaagtta acggctttat tgccctcgtt ctggtagctg ccgtcgtcgg atttgccgaa
    11221 gggatggatg cacaggccgt cctgcactct atacaaaatg gtatcggcag cacgctcggc
    11281 gggctggcaa tgatcctcgg tttcggggcc atgttaggca agctgatttc tgatacgggt
    11341 gcggcacaac gtatcgccac tacgctgatt gctacttttg gtaaaaaacg cgtgcaatgg
    11401 gcgctagtga tcaccggtct ggttgtgggc ctcgccatgt tttttgaagt gggttttgtc
    11461 ctgctgttgc cgttggtatt taccatcgta gcatcatcag gattacccct gttgtatgtt
    11521 ggcgtaccaa tggtagcagc gctctctgta acccactgtt ttctgccgcc acatccaggg
    11581 cctactgcca tcgcgactat ctttgaggct aatctcggaa cgactttact gtatggattt
    11641 atcattacca ttccgacagt tattgtcgca ggaccgctgt tttctaaact gctaactcgc
    11701 tttgagaaag caccaccgga aggcttattt aatcctcatc tgtttagcga agaggagatg
    11761 ccctccttct ggaacagtat tttcgctgcc gtgatcccgg tcatcctgat ggctatcgcc
    11821 gccgtttgtg aaattacgtt accgaaaact aacaccgtgc gcctcttctt tgaatttgtc
    11881 ggtaaccctg ccgttgcgct gtttattgcc attgttattg cgattttcac actgggccga
    11941 cgtaatggac gcaccatcga gcaaatcatg gatatcattg gggattctat aggcgctatc
    12001 gcgatgattg tgtttattat cgctggcggc ggcgcgttta agcaggtatt agtagatagc
    12061 ggtgtcgggc actatatttc acacttaatg accggaacta cactttcgcc gttattgatg
    12121 tgctggactg ttgcggcgct gttgcgtatc gctctgggct ctgccaccgt cgcggccatt
    12181 accaccgcgg gtgtggtgtt gccgattatc aacgttaccc atgccgatcc cgctttaatg
    12241 gtactggcaa ccggtgcggg cagcgtgatc gcgtcacacg taaacgaccc tggcttctgg
    12301 ctatttaaag ggtattttaa tctgacggtt ggtgaaacgt tgcgtacctg gacggtgatg
    12361 gaaaccctta tttctattat gggtttgctg ggcgtgttag ccattaacgc cgtattgcac
    12421 tgaaagaata aaatattgtg atgtagtttc gggggaagat tgaagattcc cccgacgttg
    12481 ggagaagtta tgcgcaatca cagaatttct ttacaggata tcgctacgct ggctggcgta
    12541 acaaaaatga ccgtgagtcg ttatatccgc tcgccgaaaa aggtggcaaa ggaaacaggc
    12601 gagcgcatcg ccaaaattat ggaagagatc aattatatcc ctaatcgcgc tcccggcatg
    12661 ttgttgaatg cacaaagtta taccctcggt atcttgattc cgtcatttca aaatcaactc
    12721 ttcgctgaca ttctcgcggg aatagaatcc gtcacctctg agcataatta tcagaccctt
    12781 attgctaatt acaattacga tcgcgattcc gaagaagagt cggtgattaa cctgctctct
    12841 tataacattg acgggattat actttcggaa aaatatcaca ccatcaggac ggtgaaattt
    12901 ctgcgttcag ccaccattcc ggtcgtggaa ttgatggatg tacagggaga acggctggat
    12961 atggaggtcg gttttgataa tcggcaggcc gcttttgaca tggtgtgtac catgctggag
    13021 aagcgagtca ggcacaaaat tctgtatctc ggttccaaag atgacacccg cgatgaacag
    13081 cgttatcagg ggtattgcga tgcgatgatg ctgcataatc tttccccatt acgcatgaat
    13141 ccacgcgcca tctcatccat tcatttagga atgcagttaa tgcgtgatgc ccttagcgca
    13201 aacccggatt tagacggtgt attttgcacc aatgacgata ttgcgatggg tgcgcttctg
    13261 ctgtgccgcg agcgaaacct cgccgtgcca gaacaaattt ccattgcggg ttttcatggg
    13321 ctggagattg gcaggcaaat gatcccaagc ctcgccagcg taattactcc ccgttttgat
    13381 attggtcgga tggccgccca aatgttgctg agcaaaatta aaaataacga tcacaaccac
    13441 aacactgttg acctcgggta tcagatttat cacggcaaca cgctttaggt tattttctct
    13501 tcattacacg tattctcttt gccggacgtt gcctatactc caggcaggaa actggaggat
    13561 atctcatgag tgaacccctg ttaattgccc gcacgccgga cacagaactg tttttactgc
    13621 cgggaatggc taaccgtcat gggctgatta ccggcgcaac ggggacgggt aaaaccgtta
    13681 cgctgcaaaa actggcggag tcattgtcgg aaatcggcgt gccggtgttt atggctgatg
    13741 tgaaaggcga tctgaccggc gtcgcgcagg caggaacggt gtcggaaaaa ctgctcgcaa
    13801 ggcttaaaaa tatcggcgtc aatgactggc aaccgcatgc caatccggtg gtggtgtggg
    13861 atatctttgg cgagaaaggc catccggtgc gggcgacggt ttcggatctg gggccgctgt
    13921 tgctggcacg actgttgaat ctcaacgatg tgcaatctgg cgtgctgaat atcatcttcc
    13981 gcattgctga cgatcagggg ctgttactgc tcgactttaa agatctgcgg gcaattaccc
    14041 agtacatcgg cgataacgcc aaatccttcc agaatcagta cggtaatatc agtagcgcat
    14101 cggttggtgc catccagcgc gggctgttgt cgctggaaca gcaaggcgca gcacacttct
    14161 ttggtgagcc gatgctggat atcaaagact ggatgcgcac cgatgccaac ggtaaaggcg
    14221 ttatcaatat cctcagcgcc gagaaacttt atcagatgcc gaaactgtac gccgccagcc
    14281 tgctgtggat gctttcagag ttgtatgaac aattgccgga agcgggcgat ctggagaaac
    14341 caaaactggt gtttttcttc gacgaggcac atctgctgtt taacgatgcc ccgcaggtac
    14401 tgctggataa gattgagcag gtgataaggc ttattcgctc aaaaggcgtg ggcgtctggt
    14461 tcgtttcgca aaacccgtct gatattccgg ataatgtgct cgggcagctc ggtaatcgcg
    14521 ttcagcatgc tttgcgggct tttacgccaa aagatcagaa agcagtgaag gcagcggcgc
    14581 aaaccatgcg ggccaatccg gcgtttgata ccgaaaaggc gattcaggaa ctgggcaccg
    14641 gcgaggcgtt gatctctttt ctggatgcga aaggaagccc ttctgtggtg gagcgtgcga
    14701 tggtgatcgc gccttgttcg cggatggggc cggtgacgga agatgagcgt aatggcttga
    14761 ttaatcactc tccggtgtat ggcaaatatg aggatgaggt ggaccgggaa tccgcctatg
    14821 agatgttgca aaaaggcttt caggccagta ccgagcagca aaataatcct cccgcgaaag
    14881 ggaaagaggt agcggtggat gacggcattc ttggtggatt gaaggatatt ttgttcggca
    14941 ctaccggacc acgcggcggg aagaaagatg gtgtggtgca aacaatggcc aaaagcgccg
    15001 ctcgccaagt gacgaatcag attgtacgcg ggatgttggg gagtttgctg ggggggagaa
    15061 gaaggtaagt caggcgagat ttgtctttgc ctgatgcgac gctggcgcgt cttatcatgc
    15121 ccaccccact gcaatatatt gaattttaat tatttttcag gaatgaacga agcacacttt
    15181 gctaacaata ataaagggag ctttcgctcc ctttattcgt tcattcggtt acgattttct
    15241 cattaacagc cacaggctga ttaagaagaa gctggcgctt ggcaacagtg cgccgatgat
    15301 cggcgggatg ccataaacca acgtcagcgg gccgaagatc tggtccagta cgtagaagac
    15361 aaaaccgaaa ctgataccgg tgaccacacg cacgcccatc ggtacgctac gcagtgggcc
    15421 aaagatgaac gacagcgcca tcagcatcat caccgccaca gatagcggct ggaagatttt
    15481 gctccacatg ttgagctgat aacgtccggc atcctgaccg ctcgacttca gatacttcac
    15541 atagttgtgc aaaccgctga tagagagtgc atccgggtcc agcgccacca cgcccagttt
    15601 gtccggcgtg aggttggttt tccaggtgcc gctcaccgtc tgcgaaccgg taatctgttt
    15661 cggattggtc agatcagatt catcaacctg cgacagacgc cagactttat gttccgggtc
    15721 aaacttcgca gtagcggcat agcgtacgga ttgcagacga cgattctcgt taaaggcata
    15781 aatgctgatg ccacctaact cttcgtcacc tttaacccgc tcaatgtaga cgaagttgtt
    15841 gccatctttc gcccataagc cttgctgggt agagagcaac gagccgccgt acatcgcctg
    15901 cgcacggtag ttacgcgcca tctgctcgcc ctgcggcgcg acccattcgc caatcgccat
    15961 cgtcagcaag accagcggaa tggcggtttt catcaccgac agcgccacct gcatacgggt
    16021 aaaaccagaa gcctgcatca ccaccagttc gctgcgctgc gccagcatcc caagaccaag
    16081 caacgcccca agcagagccg ccatcgggaa gaagatctgc acatctttcg gcacgctcag
    16141 caaggtatac attcctgcgc ctaacgcgtc gtaactcccc tgcccggctt ttttcagctg
    16201 atcgacaaac ttgataatgc ccgacagcga caccagcatg aacagtgtca tcatgatggt
    16261 ggtgaaaata gttttaccga tatagcggtc aagtacgcca aaaggttgca tcacaccgct
    16321 cctttacgcg aaaaactggc gcgcaggcgg cggaccggca cggtgtccca aaggttgaga
    16381 acaatcgcta aagccagata aatcaggtta acggtccaca tccacagcgt cgggtccagc
    16441 ttacctttac cgccgttcga tttcagggag gtctggatca ggaagaaaag tagatacagc
    16501 agcatggctg gcagcatcga cagtacgcgt ccctgacgtg ggttaaccac gctcagcggt
    16561 acgaccataa gtgccatcat aaacacggtg aataccaacg tgatacgcca gttcagttct
    16621 gcgcgagcac gatcggtgtc agtgttccac aatgtgcgca tgtccatctg gtcggtatcg
    16681 ttcgggtcga gcgccaccgc ctggtgacca atgatcgcct gataatcctg gaaatccgta
    16741 atgcggaaat cacgtaacag tgcagtgcct tcgaagcgcg ttccctggtt gagagtgacg
    16801 acctgggagc cgtcgcgcag ctgggttaaa tgtccggaat cggccaccac cacagaagga
    16861 cgtgcattac cttttggtcg aatttgcgcg aggaacacat ctttgaaatc gctgccgtca
    16921 acgctttcga tgaacagcac cgaactgcca ttagtcgctt gctggaattg cccttgcgcc
    16981 agcgccgcca tgccagggtt cgctttcgct tctgctaaca cttcatcctg atgacgcgat
    17041 gaccacggtc ccgcccacat cacgttaacc gccgcgacga ttgccgtgaa taccgcaagg
    17101 atcattgccg ctttcaccag aaccgctttg ctcaggccgc aggcatgcat taccgtaatt
    17161 tcactttcgg tatacagttt gcccagcgtc atcagcagcc cgaggaacag gcttaatggc
    17221 aggataagct gcgccatttc cggcacgccc aacccgagaa gggagagcac cagattcgcc
    17281 ggaatatcgc cgtcaaccgc tgcgccgagg atcctcacta acttttgaca gaagaagatc
    17341 aaaagcaaga tgaagagtat cgccagctgg cttttgagcg tctcccgcac cagatatctt
    17401 atgattatca ctttaaatac gcccgtaaaa actcgtcttt tgcaggattt tagcttgttt
    17461 catggcttaa acgtcattta ttctcttgag tcgtcgaaat cgtcgctaag ataattatac
    17521 tcaacggatt cacctctcag attttgttct gacgtgccaa tgccgtaata acgttaagat
    17581 taacacgaag tcatcgcaac agcggacatg agttacgaaa gcttgcaatt ctatctgtag
    17641 ccaccgccgt tgtctttaag attcaggagc gtagtgcatg gagtttagtg taaaaagcgg
    17701 tagcccggag aaacagcgga gtgcctgcat cgtcgtgggc gtcttcgaac cacgtcgcct
    17761 ttctccgatt gcagaacagc tcgataaaat cagcgatggg tacatcagcg ccctgctacg
    17821 tcggggcgaa ctggaaggaa aaccggggca gacattgttg ctgcaccatg ttccgaatgt
    17881 actttccgag cgaattctcc ttattggttg cggcaaagaa cgtgagctgg atgagcgtca
    17941 gtacaagcag gttattcaga aaaccattaa tacgctgaat gatactggct caatggaagc
    18001 ggtctgcttt ctgactgaac tgcacgttaa aggccgtaat aactactgga aagtgcgtca
    18061 ggctgtcgag acggcaaaag agacgctcta cagtttcgat cagctgaaaa cgaacaagag
    18121 cgaaccgcgt cgcccgctgc gtaaaatggt gttcaacgtg ccgacccgcc gtgaactgac
    18181 cagcggtgag cgcgcgatcc agcacggtct ggcgattgcc gccgggatta aagcagcgaa
    18241 agatctcggc aatatgccgc cgaatatctg taacgccgct tacctcgctt cacaagcgcg
    18301 ccagctggct gacagctaca gcaagaatgt tatcacccgc gttatcggcg aacagcagat
    18361 gaaagagctg gggatgcatt cctatctggc ggtcggtcag ggttcgcaaa acgaatcgct
    18421 gatgtcggtg attgagtaca aaggcaacgc gtcggaagat gcacgcccaa tcgtgctggt
    18481 gggtaaaggt ttaaccttcg actccggcgg tatctcgatc aagccttcag aaggcatgga
    18541 tgagatgaag tacgatatgt gcggtgcggc agcggtttac ggcgtgatgc ggatggtcgc
    18601 ggagctacaa ctgccgatta acgttatcgg cgtgttggca ggctgcgaaa acatgcctgg
    18661 cgggcgtgcc tatcgtccgg gcgatgtgtt aaccaccatg tccggtcaaa ccgttgaagt
    18721 gctgaatacc gacgctgaag gccgcctggt actgtgcgac gtgttaactt acgttgagcg
    18781 ttttgagccg gaagcggtga ttgacgtggc gacgctgacc ggtgcctgcg tgatcgcgct
    18841 gggtcatcac attaccggtc tgatggcgaa ccataatccg ctggcccatg aactgattgc
    18901 cgcgtctgaa caatccggtg accgcgcatg gcgcttaccg ctgggtgacg agtatcagga
    18961 acaactggag tccaattttg ccgatatggc gaacattggc ggtcgtcctg gtggggcgat
    19021 taccgcaggt tgcttcctgt cacgctttac ccgtaagtac aactgggcgc acctggatat
    19081 cgccggtacc gcctggcgtt ctggtaaagc aaaaggcgcc accggtcgtc cggtagcgtt
    19141 gctggcacag ttcctgttaa accgcgctgg gtttaacggc gaagagtaat tgcgtcaggc
    19201 aaggctgtta ttgccggatg cggcgtgaac gccttatccg acctacacag cactgaactc
    19261 gtaggcctga taagacgcgc aagcgtcgca tcaggcaatg ctgttattgt cggatgcggc
    19321 atgaacgcct tatccgacct acacagcacc gaactcgtag gcctgataag acgcggcagc
    19381 gtcgcatcag gcaatgctgt tattgtcgga tgcggcgtga gcgccttatc cgacctacac
    19441 acagcactga actcgtaggc ctgataagac acaacagcgt cgcatcaggc gctgcggtgt
    19501 atacctgatg cgtatttaaa tccaccacaa gaagccccat atatgaaaaa cgcaacgttc
    19561 taccttctgg acaatgacac caccatcgat ggcttaagcg ccgttgagca gctggtgtgt
    19621 gaaattgccg cagaacgttg gcgcagcggt aagcgcgtgc tcatcgcctg tgaagatgaa
    19681 aagcaggctt accggctgga tgaagccctg tgggcgcgtc cggcagaaag ctttgttccg
    19741 cataatttag cgggagaagg accgcgcggc ggtgcgccgg tggagatcgc ctggccgcaa
    19801 aaacgcagca gcagcccgcg cgatatattg attagtctgc gaacaagctt tgcagatttt
    19861 gccaccgctt tcacagaagt ggtagacttc gttccttatg aagattctct gaaacaactg
    19921 gcgcgcgaac gctataaagc ctaccgcgtg gctggtttca acctgaatac ggcaacctgg
    19981 aaataatgga aaagacatat aacccacaag atatcgaaca gccgctttac gagcactggg
    20041 aaaagcaggg ctactttaag cctaatggcg atgaaagcca ggaaagtttc tgcatcatga
    20101 tcccgccgcc gaacgtcacc ggcagtttgc atatgggtca cgccttccag caaaccatca
    20161 tggataccat gatccgctat cagcgcatgc agggcaaaaa caccctgtgg caggtcggta
    20221 ctgaccacgc cgggatcgct acccagatgg tcgttgagcg caagattgcc gcagaagaag
    20281 gtaaaacccg tcacgactac ggccgcgaag ctttcatcga caaaatttgg gaatggaaag
    20341 cggaatccgg cggcaccatt acccgtcaga tgcgccgtct cggcaactcc gtcgactggg
    20401 agcgtgaacg cttcaccatg gacgaaggcc tgtccaatgc ggtgaaagaa gttttcgttc
    20461 gtctatataa agaagacctg atttaccgtg gcaaacgcct ggtaaactgg gacccgaaac
    20521 tgcgcaccgc tatctctgac ctggaagtgg aaaaccgcga atcgaaaggt tcgatgtggc
    20581 acatccgcta tccgctggct gacggtgcga aaaccgcaga cggtaaagat tatctggtgg
    20641 tcgcgactac ccgtccggaa accctgctgg gcgatactgg cgtagccgtt aacccggaag
    20701 atccgcgtta caaagatctg attggcaaat atgtcattct gccgctggtt aaccgtcgta
    20761 ttccgatcgt tggcgacgaa cacgccgaca tggaaaaagg caccggctgc gtgaaaatca
    20821 ctccggcgca cgactttaac gactatgaag tgggtaaacg tcacgcgctg ccgatgatca
    20881 acatcctgac ctttgacggc gatatccgtg aaagcgccca ggtgttcgat accaaaggta
    20941 acgaatctga cgtttattcc agcgagatcc cggcagaatt ccagaaactg gagcgttttg
    21001 ccgcacgtaa agcagtcgtt gctgcggttg acgcactcgg cctgctggaa gaaattaaac
    21061 cgcacgacct gaccgttcct tacggcgacc gtggcggcgt ggttatcgaa ccaatgctga
    21121 ccgaccagtg gtacgtacgt gccgatgtac tggcgaagcc ggcggttgaa gcggttgaga
    21181 acggcgacat tcagttcgta ccgaagcagt acgaaaacat gtatttctcc tggatgcgcg
    21241 atattcagga ctggtgtatc tctcgtcagc tgtggtgggg tcaccgtatc ccggcatggt
    21301 atgacgaagc gggtaatgtt tatgttggcc gcaacgaaga agaagtgcgc aaggaaaata
    21361 acctcggtgc cgacgttgcc ctgcgtcagg acgaagacgt tctcgacacc tggttctctt
    21421 ctgcgctgtg gaccttctct acccttggct ggccggaaaa caccgacgcc ctgcgtcagt
    21481 tccacccaac cagcgtgatg gtatccggct tcgacatcat cttcttctgg attgcccgca
    21541 tgatcatgat gaccatgcac ttcatcaaag atgaaaatgg caaaccgcag gtgccgttcc
    21601 acaccgttta catgaccggc ctgattcgtg atgacgaagg ccagaagatg tctaaatcca
    21661 agggtaacgt tattgatccg ctggatatgg ttgacggtat ttcgctgcca gaactgctgg
    21721 aaaaacgtac cggcaatatg atgcagccgc agctggcgga caaaatccgt aagcgcaccg
    21781 agaagcagtt cccgaacggt attgagccgc acggtactga cgcgctgcgc ttcaccctgg
    21841 cggcgctggc gtctaccggt cgtgacatca actgggatat gaagcgtctg gaaggttacc
    21901 gtaacttctg taacaagctg tggaacgcca gccgctttgt gctgatgaac acggaaggtc
    21961 aggattgcgg ctttaacggc ggtgaaatga cgctgtcgct ggcggatcgc tggattctgg
    22021 ctgagttcaa ccagaccatc aaagcgtacc gcgaagcgct ggacagcttc cgcttcgata
    22081 tcgctgcagg cattctgtat gagttcacct ggaaccagtt ctgtgactgg tatctggagc
    22141 tgactaagcc ggtaatgaac ggtggaaccg aagccgaact gcgcggtact cgccatacgc
    22201 tggtgaccgt actggaaggt ctgctgcgcc tcgcgcatcc gatcattccg ttcatcaccg
    22261 aaaccatctg gcagcgtgtg aaagtacttt gcggtatcac tgccgacacc atcatgctgc
    22321 agccgttccc gcagtacgat gcatctcagg ttgatgaagc cgcactggcc gacaccgaat
    22381 ggctgaaaca ggcgatcgtt gcggtacgta acatccgtgc agaaatgaat atcgcgccgg
    22441 gcaaaccgct ggagctgctg ctgcgtggtt gcagcgcgga tgcagaacgt cgcgtaaatg
    22501 aaaaccgtgg cttcctgcaa accctggcgc gtctggaaag catcaccgtg ctgcctgccg
    22561 atgacaaagg tccggtttcc gttgcgaaga tcatcgacgg cgcagagctg ctgatcccga
    22621 tggctggcct catcaacaaa gaagatgagc tggcgcgtct ggcgaaagaa gtggcgaaga
    22681 tcgaaggcga aatcagccgt atcgagaaca agctggcgaa tgaaggcttt gtcgcccgcg
    22741 caccggaagc ggtcatcgcg aaagagcgtg agaagctgga aggctatgca gaagcgaaag
    22801 ctaagctgat tgaacagcag gctgttatcg ccgcgctgta atcaaaacac agtgatgaaa
    22861 acgaaggccg gagcatgctc cggccttttt tatctcttac agaaatggta aagaaggcat
    22921 aattccccgt gaaatactgg ctaagaagcc tttatctggt tgttcttctt tattgattaa
    22981 aggaaggtca tccaaatcgc ccagcaaata cgtatttttt gcctgccagt caatcatcca
    23041 tattttcagc agtggataag ccagaccgcc cgtaatcccg gatatcacca ccaacgcaca
    23101 catgcgataa agcataccgt ggtatgttaa agttgagcga aaacgaatac gcccatcatt
    23161 cagtgacagg ttgctcataa aatgatttcg caacgacacc gttaaataac tggtgctaac
    23221 agcaatccca aaataataga ttaactgcgc gattatcatt ttacgttgca tttccataaa
    23281 ttgctgtaaa ttctcaatat catcatttgc atacacagaa ctatcatacg catttaatat
    23341 ttgatcgaag ataatataac cagcaacagc gagaaaaggt aataaagcta aaaatgcgag
    23401 aatggcatat tttatacaat acgtagtatc taatttcacc ttgaaacgat gtataccgaa
    23461 actggtattg ctccagagaa aactcattac cagactatat aaagtaccat taaaaatacc
    23521 aatggaaaca ataccaacta ttgccatcag aaccacagat ataataacac tacttgaact
    23581 attggcatgt agcatctttg tcgagataaa gaaaacagtc cccatcccaa tggccattaa
    23641 aatcggcaag aaaaaggtta cccaccagaa ccctttcata gagcaattaa aactaaatct
    23701 tacgccgttg agactggtca tcaaggcctg ataacgcagt ccttttgctg ccataaatat
    23761 aagcaaaacc aacagtgaca aagtcaaaac acagccaaca agcggcatat ctgctgacac
    23821 tgtcattaat attgcgaaat agaaaaaaac aaaaacaaga caactaaaaa aaacattccc
    23881 accagtaatt ccataagaaa atcgttgtcc gttaacttcc atattagcat agagataacg
    23941 cttacatttc attaatgccc atggtaaata gatacctagc gttataatcg ttaacaacac
    24001 attcaccaca caaataagaa aatatctctc acctgtacca tgaaaaacaa acgaatggga
    24061 cggaacatcc atttcattaa taacttgagc cataaaaatt ccctgaatta aaaaatccat
    24121 tgatataatt tatagataca gacagtaaaa tgttctgcca cgttacaata ctcttatcag
    24181 taa
//
LOCUS       DAPGUL010000069        23941 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.069, whole genome shotgun sequence.
ACCESSION   DAPGUL010000069 DAPGUL010000000
VERSION     DAPGUL010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23941)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23941)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23941
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.069"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..3879)
                     /gene="entF"
                     /locus_tag="RHX21_002899"
     CDS             complement(<1..3879)
                     /gene="entF"
                     /locus_tag="RHX21_002899"
                     /EC_number="6.3.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin non-ribosomal peptide synthetase
                     EntF"
                     /protein_id="HDV1988052.1"
                     /translation="MSQHLPLVAAQPGIWMAEKLSDLPSAWSVAHYVELTGDVDAPLL
                     ARAVVVGLAQADTLRMRFTEDNGEVWQWVDDALIFELPEIIDLRTNIDPHGTAQVLML
                     ADLQQDLRVDSGKPLVFHQLIHVADNRWYWYQRYHHLLVDGFSFPAITRQIANIYCTW
                     LRGEPTPASPFTPFADVVEEYQQYRESEAWQRDAAFWAEQRRQLPPPASLSPAPLAGR
                     SASADILRLKLEFTDGEFRQLATQLSGVQRTDLALALAALWLGRLCNRMDYAAGFIFM
                     RRLGSAALTASGPVLNVLPLGIHIAAQETLPELATRLAAQLKKMRRHQRYDAEQIVRD
                     SGRAAGEEPLFGPVLNIKVFDYQLDIPGVQTQTHTLATGPVNDLELALFPDEHGDLSI
                     EILANKQRYDEPTLIQHAERLKMLIAQFAADPALLCGDVDIMLPGEYAQLAQINATQV
                     EIPETTLSALVAEQAAKTPDAPALADARYLFSYREMREQVVALANLLRERGVKPGDSV
                     AVALPRSVFLTLALHAIVEAGAAWLPLDTGYPDDRLKMMLEDARPSLLITTDDQLPRF
                     SDVPNLTSLCYNAPLTPQGSAPLQLSQPHHTAYIIFTSGSTGRPKGVMVGQTAIVNRL
                     LWMQNHYPLTGEDVVAQKTPCSFDVSVWEFFWPFIAGAKLVMAEPEAHRDPLAMQQFF
                     AEYGVTTTHFVPSMLAAFVASLTPQTARQSCATLKQVFCSGEALPADLCREWQQLTGA
                     PLHNLYGPTEAAVDVSWYPAFGEELAQVRGSSVPIGYPVWNTGLRILDAMMHPVPPGV
                     AGDLYLTGIQLAQGYLGRPDLTASRFIADPFAPGERMYRTGDVARWLDNGAVEYLGRS
                     DDQLKIRGQRIELGEIDRVMQALPDVEQAVTHACVINQAAATGGDARQLVGYLVSQSG
                     LPLDTSALQAQLRETLPPHMVPVVLLQLPQLPLSANGKLDRKALPLPELKTQASGRAP
                     KAGSETIIAAAFASLLGCDVQDADADFFALGGHSLLAMKLAAQLSRQFARQVTPGQVM
                     VASTVAKLATIIDGEEDSSRRMGFETILPLREGNGPTLFCFHPASGFAWQFSVLSRYL
                     DPQWSIIGIQSPRPHGPMQTATNLDEVCEAHLATLLEQQPHGPYYLLGYSLGGTLAQG
                     IAARLRARGEQVAFLGLLDTWPPETQNWQEKEANGLDPEVLAEINREREAFLAAQQGS
                     TSTELFTTIEGNYADAVRLLTTAHSVPFDGKATLFVAERTLQEGMSPERAWSPWIAEL
                     DIYRQDCAHVDIISPGAFEKIGPIIRATLNR"
     gene            complement(3876..4094)
                     /gene="ybdZ"
                     /locus_tag="RHX21_002900"
     CDS             complement(3876..4094)
                     /gene="ybdZ"
                     /locus_tag="RHX21_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin biosynthesis protein YbdZ"
                     /protein_id="HDV1988053.1"
                     /translation="MAFSNPFDDPQGAFYILRNAQGQFSLWPQQCALPAGWDIVCQPQ
                     SQASCQQWLEVHWRTLTPANFTQLQEAQ"
     gene            complement(4097..5299)
                     /gene="fes"
                     /locus_tag="RHX21_002901"
     CDS             complement(4097..5299)
                     /gene="fes"
                     /locus_tag="RHX21_002901"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308651.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterochelin esterase"
                     /protein_id="HDV1988054.1"
                     /translation="MTALKVGSESWWQSKHGPEWQRLNDEMFEVTFWWRDPQGSEEYS
                     TIKRVWIYITGVTDHHQNSQPQSMQRIAGTDVWQWTTQLNANWRGSYCFIPTERDDIF
                     SAPSPDRLELREGWRKLLPQAIADPLNPQSWKGGRGHAVSALEMPQAPLQPGWDCPQA
                     PEIAAKEIIWKSERLKNSRRVWIFTTGDATAEERPLAVLLDGEFWAQSMPVWPVLTSL
                     THRQQLPPAVYVLIDAIDTTHRAHELPCNADFWLAVQQELLPLVKAIAPFSDRADRTV
                     VAGQSFGGLSALYAGLHWPERFGCVLSQSGSYWWPHRGGQQEGVLLEKLKAGEVSAEG
                     LRIVLEAGIREPMIMRANQALYAQLHPIKESIFWRQVDGGHDALCWRGGLMQGLIDLW
                     QPLFHDRS"
     gene            5542..7782
                     /gene="fepA"
                     /locus_tag="RHX21_002902"
     CDS             5542..7782
                     /gene="fepA"
                     /locus_tag="RHX21_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore enterobactin receptor FepA"
                     /protein_id="HDV1988055.1"
                     /translation="MNKKIHSLALLVNLGIYGVAQAQEPTDTPVSHDDTIVVTAAEQN
                     LQAPGVSTITADEIRKNPVARDVSEIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPE
                     NTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAA
                     GGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRLYGNLD
                     KTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELEAGYS
                     RQGNLYAGDTQNTNSDAYTRSKYGDETNRLYRQNYALTWNGGWDNGVTTSNWVQYEHT
                     RNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEWN
                     QQRMKDLSSNTQALTGANTGGAIDGVSATDRSPYSKAEIFSLFAENNMELTDSTIVTP
                     GLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQG
                     CYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGYVAVG
                     QNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLSII
                     PEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLS
                     ATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYM
                     SVNTHF"
     gene            7957..8577
                     /gene="entD"
                     /locus_tag="RHX21_002903"
     CDS             7957..8577
                     /gene="entD"
                     /locus_tag="RHX21_002903"
                     /EC_number="6.3.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415115.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin synthase subunit EntD"
                     /protein_id="HDV1988056.1"
                     /translation="MKTTHTSLPFAGHTLHFVEFDPANFCEQDLLWLPHYAQLQHAGR
                     KRKAEHLAGRIAAIYALREYGYKCVPAIGELRQPVWPAEVYGSISHCGATALAVVSRQ
                     PIGVDIEEIFSAQTATELTDNIITPAEHERLADCGLAFSLALTLAFSAKESAFKASEI
                     QTDAGFLDYQIISWNKQQVIIHRENEMFAVHWQIKEKIVITLCQHD"
     gene            complement(8699..8851)
                     /gene="hokE"
                     /locus_tag="RHX21_002904"
     CDS             complement(8699..8851)
                     /gene="hokE"
                     /locus_tag="RHX21_002904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308648.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokE"
                     /protein_id="HDV1988057.1"
                     /translation="MLTKYALVAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKAVL
                     AYEPKK"
     gene            complement(9202..9354)
                     /gene="hokE"
                     /locus_tag="RHX21_002905"
     CDS             complement(9202..9354)
                     /gene="hokE"
                     /locus_tag="RHX21_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001342976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokE"
                     /protein_id="HDV1988058.1"
                     /translation="MLTKYALAAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKVVL
                     AYEPKK"
     gene            9796..10914
                     /locus_tag="RHX21_002906"
     CDS             9796..10914
                     /locus_tag="RHX21_002906"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HDV1988059.1"
                     /translation="MPLPDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDAVKNE
                     ITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAAADHHLEICGGGTHPF
                     QKWQRQEVCENERYQRTLENFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPH
                     FIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFEALFRCLSYTTMID
                     SIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKHQEKD
                     YLLYKFNRFQACRYGLEGVITDPHTGDRRPLTEDTLRLLEKIAPSAHKMGASSAIEAL
                     HRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGD"
     gene            10980..11228
                     /locus_tag="RHX21_002907"
     CDS             10980..11228
                     /locus_tag="RHX21_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1158 domain-containing protein"
                     /protein_id="HDV1988060.1"
                     /translation="MKHPLETLTTAAGILLMAFLSCLLLPAPALRLTLAQKLVTMFHL
                     MDLSQLYTLLFCLWFLVLGAIEYFVLRFIWRRWFSLAD"
     gene            11293..11661
                     /locus_tag="RHX21_002908"
     CDS             11293..11661
                     /locus_tag="RHX21_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HDV1988061.1"
                     /translation="MDKQSLHETAKRLALELPFVELCWPFGPEFDVFKIGGKIFMLSS
                     ELRGVPFINLKSDPQKSLLNQQIYPSIKPGYHMNKKHWISVYPGEEISEALLRDLIND
                     SWNLVVDGLAKRDQKRVRPG"
     gene            11755..12408
                     /gene="nfsB"
                     /locus_tag="RHX21_002909"
     CDS             11755..12408
                     /gene="nfsB"
                     /locus_tag="RHX21_002909"
                     /EC_number="1.5.1.34"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-insensitive NAD(P)H nitroreductase"
                     /protein_id="HDV1988062.1"
                     /translation="MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQ
                     PWHFIVASTEEGKARVAKSAAGNYVFNERKILDASHVVVFCAKTAMDDAWLKLVVDQE
                     DADGRFATPEAKAANDKGRKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLD
                     AVPIEGFDAAILDAEFGLKEKGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV"
     gene            12516..13763
                     /gene="ybdG"
                     /locus_tag="RHX21_002910"
     CDS             12516..13763
                     /gene="ybdG"
                     /locus_tag="RHX21_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel YbdG"
                     /protein_id="HDV1988063.1"
                     /translation="MQDLISQVEDLAGIEIDHTTSMVMIFGIIFLTAVVVHIILHWVV
                     LRTFEKRAIASSRLWLQIITQNKLFHRLAFTLQGIIVNIQAVFWLQKGTEAADILTTC
                     AQLWIMMYALLSVFSLLDVILNLAQKFPAASQLPLKGIFQGIKLIGAILVGILMISLL
                     IGQSPAILISGLGAMAAVLMLVFKDPILGLVAGIQLSANDMLKLGDWLEMPKYGADGA
                     VIDIGLTTVKVRNWDNTITTIPTWSLVSDSFKNWSGMSASGGRRIKRSISIDVTSIRF
                     LDEDEMQRLNKAHLLKPYLTSRHQEINEWNRQQGSTESILNLRRMTNIGTFRAYLNEY
                     LRNHPRIRKDMTLMVRQLAPGDNGLPLEIYAFTNTVVWLEYESIQADIFDHIFAIVEE
                     FGLRLHQSPTGNDIRSLAGAFKQ"
     gene            complement(13831..15207)
                     /gene="pheP"
                     /locus_tag="RHX21_002911"
     CDS             complement(13831..15207)
                     /gene="pheP"
                     /locus_tag="RHX21_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine transporter"
                     /protein_id="HDV1988064.1"
                     /translation="MKNASTVSEDTASNQEPTLHRGLHNRHIQLIALGGAIGTGLFLG
                     IGPAIQMAGPAVLLGYGVAGIIAFLIMRQLGEMVVEEPVSGSFAHFAYKYWGPFAGFL
                     SGWNYWVMFVLVGMAELTAAGIYMQYWFPDVPTWIWAAAFFIIINAVNLVNVRLYGET
                     EFWFALIKVLAIIGMIGFGLWLLFSGHGGEKASIDNLWRYGGFFATGWNGLILSLAVI
                     MFSFGGLELIGITAAEARDPEKSIPKAVNQVVYRILLFYIGSLVVLLALYPWVEVKSN
                     SSPFVMIFHNLDSNVVASALNFVILVASLSVYNSGVYSNSRMLFGLSVQGNAPKFLTR
                     VSRRGVPINSLMLSGAITSLVVLINYLLPQKAFGLLMALVVATLLLNWIMICLAHLRF
                     RAAMRRQGRETQFKALLYPFGNYLCIAFLGMILLLMCTMDDMRLSAILLPVWIVFLFV
                     AFKTLRRK"
     gene            complement(15309..18452)
                     /gene="cusA"
                     /locus_tag="RHX21_002912"
     CDS             complement(15309..18452)
                     /gene="cusA"
                     /locus_tag="RHX21_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter permease
                     subunit CusA"
                     /protein_id="HDV1988065.1"
                     /translation="MIEWIIRRSVANRFLVLMGALFLSIWGTWTIINTPVDALPDLSD
                     VQVIIKTSYPGQAPQIVENQVTYPLTTTMLSVPGAKTVRGFSQFGDSYVYVIFEDGTD
                     PYWARSRVLEYLNQVQGKLPAGVSAELGPDATGVGWIYEYALVDRSGKHDLADLRSLQ
                     DWFLKYELKTIPDVAEVASVGGVVKEYQVVIDPQRLAQYGISLAEVKSALDASNQEAG
                     GSSIELAEAEYMVRASGYLQTLDDFNHIVLKASENGVPVYLRDVAKVQIGPEMRRGIA
                     ELNGEGEVAGGVVILRSGKNAREVIAAVKDKLETLKSSLPEGMEIVTTYDRSQLIDRA
                     IDNLSGKLLEEFIVVAVVCALFLWHVRSALVAIISLPLGLCIAFIVMYFQGLNANIMS
                     LGGIAIAVGAMVDAAIVMIENAHKRLEEWQHQHPDATLDNKTRWQVITDASVEVGPAL
                     FISLLIITLSFIPIFTLEGQEGRLFGPLAFTKTYAMAGAALLAIVVIPILMGYWIRGK
                     IPPESSNPLNRFLIRVYHPLLLKVLHWPKTTLLVTALSVLTVLWPLNKVGGEFLPQIN
                     EGDLLYMPSTLPGISAAEAASMLQKTDKLIMSVPEVARVFGKTGKAETATDSAPLEMV
                     ETTIQLKPQDQWRPGMTMDKIIEELDNTVRLPGLANLWVPPIRNRIDMLSTGIKSPIG
                     IKVSGTVLADIDAMAEQIEEVARTVPGVASALAERLEGGRYINVEINREKAARYGMTV
                     ADVQLFVTSAVGGAMVGETVEGIARYPINLRYPQSWRDSPQALRQLPILTPMKQQITL
                     ADVADVKVSTGPSMLKTENARPTSWIYIDARDRDMVSVVHDLQKAIAEKVQLKPGTSV
                     AFSGQFELLERANHKLKLMVPMTLMIIFVLLYLAFRRVGEALLIISSVPFALVGGIWL
                     LWWMGFHLSVATGTGFIALAGVAAEFGVVMLMYLRHAIEAEPSLNNPQTFSEQKLDEA
                     LYHGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITAPLLSLFI
                     IPAAYKLMWLHRHRVRK"
     gene            complement(18464..19687)
                     /gene="cusB"
                     /locus_tag="RHX21_002913"
     CDS             complement(18464..19687)
                     /gene="cusB"
                     /locus_tag="RHX21_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter periplasmic
                     adaptor subunit CusB"
                     /protein_id="HDV1988066.1"
                     /translation="MKKIALIIGSMIAGGIISAAGFTWVAKAEPPAEKTSTAERKILF
                     WYDPMYPNTRFDKPGKSPFMDMDLVPKYADEESSASGVRIDPTQTQNLGVKTATVTRG
                     PLTFAQSFPANVSYNEYQYAIVQARAAGFIDKVYPLTVGDKVQKGTPLLDLTIPDWVE
                     AQTEYLLLRETGGTATQTEGILERLRLAGMPEADIRRLIATQKIQTRFTLKAPIDGVI
                     TAFDLRAGMNIAKDNVVAKIQGMDPVWVTAAIPESIAWLVKDASQFTLTVPARPDKTL
                     TIRKWTLLPGVDAATRTLQLRLEVDNADEALKPGMNAWLQLNTASEPMLLIPSQALID
                     TGSEQRVITVDADGRFVPKRVAVFQASQGVTALRSGLAEGEKVVSSGLFLIDSEANIS
                     GALERMRSESATHAH"
     gene            complement(19703..20035)
                     /gene="cusF"
                     /locus_tag="RHX21_002914"
     CDS             complement(19703..20035)
                     /gene="cusF"
                     /locus_tag="RHX21_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter periplasmic
                     metallochaperone CusF"
                     /protein_id="HDV1988067.1"
                     /translation="MKKALQVAMFSLFTVIGFNAQANEHHHETMSEVQPQVISATGVV
                     KGIDLESKKITIHHDPIAAVNWPEMTMRFTITPQTKMSEIKTGDKVAFNFVQQGNLSL
                     LQDIKVSQ"
     gene            complement(20059..21441)
                     /gene="cusC"
                     /locus_tag="RHX21_002915"
     CDS             complement(20059..21441)
                     /gene="cusC"
                     /locus_tag="RHX21_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter outer
                     membrane channel CusC"
                     /protein_id="HDV1988068.1"
                     /translation="MSPCKLLPFCVALALTGCSLAPDYQRPAMPVPQQFSLSQNGLVN
                     AADNYQNAGWRTFFVDNQVKTLISEALVNNRDLRMATLKVQEARAQYRLTDADRYPQL
                     NGEGSGSWSGNLKGNTATTREFSTGLNASFDLDFFGRLKNMSEAERQNYLATEEAQRA
                     VHILLVSNVAQSYFNQQLAYAQLQIAEETLRNYQQSYAFVEKQLLTGSSNVLALEQAR
                     GVIESTRSDIAKRQGELAQANNALQLLLGSYGKLPQAQTVNSDSLQSVKLPAGLSSQI
                     LLQRPDIMEAEHALMAANANIGAARAAFFPSISLTSGISTASSDLSSLFNASSGMWNF
                     IPKIEIPIFNAGRNQANLDIAEIRQQQSVVNYEQKIQNAFKEVADALALRQSLNDQIS
                     AQQRYLASLQITLQRARALYQHGAVSYLEVLDAERSLFATRQTLLDLNYARQVNEISL
                     YTALGGGWQQ"
     gene            21598..22281
                     /gene="cusR"
                     /locus_tag="RHX21_002916"
     CDS             21598..22281
                     /gene="cusR"
                     /locus_tag="RHX21_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper response regulator transcription factor
                     CusR"
                     /protein_id="HDV1988069.1"
                     /translation="MKLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGD
                     YDLIILDIMLPDVNGWDIVRMLRSANKGMPILLLTALGTIEHRVKGLELGADDYLMKP
                     FAFAELLARVRTLLRRGAAVIIESQFQVADLMVDLVSRKVTRSGTRITLTSKEFTLLE
                     FFLRHQGEVLPRSLIASQVWDMNFDSDTNAIDVAVKRLRGKIDNDFEPKLIQTVRGVG
                     YMLEVPDGQ"
     gene            22271..23719
                     /gene="cusS"
                     /locus_tag="RHX21_002917"
     CDS             22271..23719
                     /gene="cusS"
                     /locus_tag="RHX21_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001739168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) sensor histidine kinase CusS"
                     /protein_id="HDV1988070.1"
                     /translation="MVSKPFQRPFSLATRLTFFISLATIAAFFAFAWIMIHSVKVHFA
                     EQDINDLKEISATLERVLNHPDETQARRLMTLEDIVSGYSNVLISLADSHGKTVYHSP
                     GAPDIREFTRDAIPDKDARGGEVYLLSGPTMMMPGHGHGHMEHSNWRMINLPVGPLVD
                     GKPIYTLYIALSIDFHLHYINDLMNKLIMTASVISILIVFIVLLAVHKGHAPIRSVSR
                     QIQNITSKDLDVRLDPQTVPIELEQLVLSFNHMIERIEDVFTRQSNFSADIAHEIRTP
                     ITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQLIPEKK
                     MLNLADEVGKVFDFFEALAEDRGVELRFVGDKCQVAGDPLMLRRALSNLLSNALRYTP
                     PSEAIVVRCQTVNHQVQVSVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIGLA
                     IVKSIVVAHKGTVAVTSDARGTRFVIMLPERE"
BASE COUNT         5751 a         6533 c         6090 g         5567 t
ORIGIN      
        1 cctgtttagc gttgcgcgaa taatcggccc aattttttca aacgcccctg gagagataat
       61 atccacatgc gcacaatcct gacgatagat atccagctcc gctatccacg gcgaccaggc
      121 gcgttcggga ctcatacctt cctgaagtgt gcgttcagca acaaacagcg tcgctttacc
      181 gtcaaacggt acgctatgag cagtcgtcag caggcgcaca gcatcagcgt agttgccttc
      241 aatggtggta aacaactccg ttgaagtact tccctgctgt gctgccagga aggcctcgcg
      301 ttcgcggtta atctccgcca gcacttccgg gtccagacca ttagcttctt tttcctgcca
      361 gttttgcgtt tctggcggcc aggtatccag caagccaaga aatgccacct gttcgccacg
      421 ggcacgcagt cgcgccgcaa taccctgcgc cagcgtaccg ccaagggaat accccagcag
      481 gtaataaggg ccgtgcggtt gttgctcaag taacgttgcc agatgcgctt cgcagacttc
      541 atccaggttt gtcgctgtct gcatgggtcc atgagggcgc ggcgactgaa tgccaataat
      601 cgaccattgt ggatcgagat aacgcgagag cacgctaaac tgccaggcaa aaccggacgc
      661 cggatggaaa caaaacagcg tcgggccatt accttcacgc aacggcagaa tggtttcgaa
      721 tcccatgcgc cgggagctgt cctcttcacc atcaataatc gttgccagtt tggcgacggt
      781 tgacgcgacc atcacctgcc ccggcgtcac ctgacgagca aactgtcgac ttaactgcgc
      841 tgctagtttc attgccagta gcgaatgacc gcccagcgca aagaaatcag catcggcatc
      901 ctgcacgtca caacccagca acgacgcgaa tgccgcggcg ataatcgttt cactgcccgc
      961 tttcggtgca cgtcccgacg cttgtgtctt cagttcaggc aacggtaagg ctttgcgatc
     1021 cagcttgccg ttggcgctaa gcggcaactg cggaagttgc agcagaacga ccggcaccat
     1081 atgcggcggc aatgtttcgc gaagctgtgc ctgtaatgcg ctggtatcca acggcagtcc
     1141 cgattgcgac accagatagc ccaccaactg acgcgcatca ccaccggtgg ctgccgcctg
     1201 gttaatcaca caggcgtggg taactgcctg ttcgacatcc ggcagcgcct gcatcacgcg
     1261 atcgatttcg cccagttcga tacgctgccc gcgaattttt agctgatcgt cactgcgccc
     1321 gaggtactcc accgcgccgt tatccagcca gcgggcgacg tctccggtac gatacatccg
     1381 ttcacctggg gcaaaaggat cggcaataaa acggctggcg gtcagatcgg gtcgtccaag
     1441 atacccctgc gccagttgga tgccggtgag atagagatca cccgccacac ccggcggcac
     1501 cggatgcatc atcgcatcaa gaatacgcag acccgtattc cataccggat aaccaatcgg
     1561 cacactgctg ccgcgcacct gtgccagttc ctcgccaaaa gccggatacc agctgacatc
     1621 taccgccgct tccgtcgggc catatagatt atgcaacggc gcgccagtta actgttgcca
     1681 ttcgcggcat aaatcagccg gtaaggcctc accactacag aaaacctgtt tcaacgtcgc
     1741 gcaactctgg cgagcggttt gcggcgtcag cgaggcaaca aatgccgcca gcatcgacgg
     1801 cacaaagtgc gtggtcgtta cgccatattc ggcaaagaat tgctgcatag cgagcgggtc
     1861 gcggtgcgct tccggttcag ccatcaccag tttcgccccg gcaataaacg gccagaaaaa
     1921 ctcccacacc gagacatcaa aactgcacgg cgttttttgg gcaacgacat cttcgcctgt
     1981 aagcgggtaa tggttttgca tccaaagcaa gcggttaacg atagccgtct gcccgaccat
     2041 tacccctttc ggcctgccgg tggagccaga ggtaaagatg atataagccg tgtggtgcgg
     2101 ttgtgaaagt tgcagcggcg cactgccctg gggggtaagc ggggcgttat agcaaaggct
     2161 tgttaaattg ggaacatcgc taaagcgcgg cagttgatcg tcggtggtaa ttaacagcga
     2221 cggacgcgca tcttccagca tcattttcag gcgatcgtcc ggatagccgg tatccagcgg
     2281 tagccaggcc gcgccagctt caactattgc atggagtgcc agggtcaaaa agaccgagcg
     2341 cggtagtgcc accgccacgc tgtcccctgg tttaacgccg cgctcacgca gcagattcgc
     2401 cagcgccacc acctgctcgc gcatttcccg atagctgaac aggtaacgcg catctgccag
     2461 cgccggagca tccggtgttt ttgccgcttg ttctgccacc agcgcgctca gcgtggtttc
     2521 tggaatctca acctgagtgg cgttgatctg cgccagctgc gcatactcac ctggcagcat
     2581 aatatcgaca tcgccgcaca acagcgccgg atccgcggcg aactgggcaa tcagcatttt
     2641 caggcgttca gcatgctgga ttaacgttgg ctcatcgtaa cgctgtttat tggcgaggat
     2701 ctcaatactc aaatcaccgt gttcatccgg gaacagggcc agttcaaggt cattaaccgg
     2761 accggttgcc agggtatggg tttgcgtctg aacaccagga atatccagtt ggtaatcaaa
     2821 taccttgata ttgagtaccg gaccgaacag cggttcctct cctgccgctc gcccgctgtc
     2881 acggacaatt tgttcggcat cgtaacgttg atgacgacgc atttttttca gttgtgctgc
     2941 cagtcgggtt gccagttccg gcagcgtttc ttgcgccgca atgtgaatac ccaacggtaa
     3001 aacgttgagc acgggtccgc tagccgtcag cgccgccgag cccagtcgac gcataaagat
     3061 aaatccggcg gcatagtcca tgcgattgca caatcgcccc agccacaagg ctgccagcgc
     3121 aagggctaaa tcggtacgct gcacacctga aagttgcgta gccagctggc ggaattcccc
     3181 gtcggtaaat tccagtttca ggcgcagaat atctgccgaa gcgctgcgcc ccgctaaagg
     3241 tgccggagaa agtgacgcgg gcggcggcag ttgacgacgc tgttctgccc agaatgccgc
     3301 atcacgctgc caggcttcgc tttcgcggta ttgctggtac tcttccacta catcagcgaa
     3361 aggcgtaaac ggcgaagcag gcgttggttc gccacgcagc catgtgcagt aaatattggc
     3421 gatctggcga gtaatggccg ggaaactgaa gccatcgacc agcaaatggt gataacgctg
     3481 ataccagtac cagcggttat ccgcaacatg tatcagctga tgaaagacca gtggtttacc
     3541 gctatcgacg cgcaaatctt gttgcaaatc cgccagcatt aatacctgcg cagtaccgtg
     3601 cggatcaata ttggttcgca ggtcgataat ttctggcagt tcgaatatca gcgcatcatc
     3661 gacccactgc cagacttcgc cgttatcttc cgtaaaacgc atccgcaacg tatctgcttg
     3721 cgctagtccg acaaccaccg cgcgggccag taatggcgca tcaacatctc cagttaactc
     3781 aacgtaatgc gccacgctcc aggcggaggg taaatccgac agtttttctg ccatccagat
     3841 gccgggctgt gcggcgacca aaggtaaatg ctggctcatt gtgcctcctg caactgggtg
     3901 aaattggccg gtgtcagagt acgccagtgg acttccagcc actgctggca ggacgcctgt
     3961 gactgcggct gacacacaat gtcccagcct gccggtaagg cgcattgttg cggccacaga
     4021 ctgaattgcc cctgcgcatt gcgcaaaatg taaaacgctc cctgtggatc atcgaaggga
     4081 ttactgaatg ccatattcaa ctcctgtcat ggaaaagtgg ttgccagagg tcgattagcc
     4141 cctgcatcaa gccaccgcgc caacaaagcg catcatgtcc gccgtcaacc tgacgccaga
     4201 aaatggattc ttttatgggg tgtaattgcg catacagcgc ctgattggcc cgcataatca
     4261 tcggctcgcg aatacccgct tccagcacaa tgcgcagacc ttcggcgcta acttcaccag
     4321 ctttaagctt ttcaagtaac acgccctctt gctgcccgcc ccgatgcggc caccagtacg
     4381 atcctgactg gcttaataca cagccaaagc gttcaggcca gtgcagtccg gcatacagcg
     4441 cggacagccc accaaaactc tgcccggcga ccacggtgcg atcggcgcga tcgctaaaag
     4501 gggcaatagc tttcaccagg ggtaataact cttgctgtac tgccagccag aaatccgcat
     4561 tacacggcag ttcgtgggcg cggtgcgtgg tgtcgatagc gtcgatcaac acatacacgg
     4621 cgggaggaag ttgctgacga tgggtcagcg aagtcagcac aggccagacg ggcatacttt
     4681 gcgcccaaaa ttcgccatcg agcaaaactg ccagcggacg ttcttctgct gttgcatcgc
     4741 cggtggtaaa aatccataca cgacgtgaat ttttcaaccg ttcacttttc cagataattt
     4801 ctttggctgc tatttctggc gcttgcggac aatcccatcc cggttgcaga ggcgcttgcg
     4861 gcatttcgag tgcagaaaca gcgtgccctc gcccgccttt ccagctttgt ggattcagcg
     4921 gatcggctat tgcctggggt aatagttttc gccagccttc acgtaattcg aggcgatcgg
     4981 gggatggtgc agaaaaaatg tcatcgcgtt cggtgggaat aaagcagtag ctgccgcgcc
     5041 agttggcatt gagttgtgtc gtccactgcc agacatcagt acctgcaatt cgctgcatcg
     5101 actggggctg gctgttctga tgatgatcgg tcacaccagt gatgtagatc catacgcgct
     5161 ttatcgtcga gtattcttca gaaccttggg gatcacgcca ccagaaagtg acctcaaaca
     5221 tttcgtcatt cagacgctgc cattccgggc catgtttcga ctgccaccag ctctcacttc
     5281 ctacttttaa cgccgtcaca ccataacccc atgtttactg tgcaattttt cattgattgc
     5341 agaaatatat tgataatatt attgataact atttgcattt gcaatagcgt aatggcgcgc
     5401 cgtgggaagc gcggacattt attaaccaac tgcactgcgt gtctttcagg atcaaaggtt
     5461 ttcgcggtag cgggatgcgt cgtgttgagg acgaccatgc ccgacagttg caattcgtgg
     5521 caaaaatgca ggaataaaac aatgaacaag aagattcatt ccctggcctt gttggtcaat
     5581 ctggggattt atggggtagc gcaggcacaa gagccgaccg atactcctgt ttcacatgac
     5641 gataccattg tcgttaccgc cgccgagcag aacttacagg cgcctggcgt ttcgaccatc
     5701 accgcagatg aaatccgcaa aaaccccgtt gcccgcgatg tgtcggagat catccgtacc
     5761 atgccaggcg ttaacctgac cggtaactcc accagtggtc agcgtgggaa taaccgacag
     5821 attgatattc gcggtatggg tccggaaaac acgctgattt tgattgacgg caagccggta
     5881 agcagccgta actcggtgcg tcagggctgg cgtggcgagc gcgatacccg tggtgatacc
     5941 tcctgggtgc cacctgaaat gattgaacgt attgaagttc tgcgtggtcc ggcagctgcg
     6001 cgttatggca acggcgcggc gggcggcgtg gttaacatca ttaccaaaaa aggcagcggt
     6061 gagtggcacg gctcctggga cgcttatttc aatgcaccag aacataaaga ggaaggtgcc
     6121 actaaacgca ccaacttcag cctgaccggt ccgctgggcg acgaattcag cttccgcttg
     6181 tatggcaacc tcgacaaaac ccaggctgac gcgtgggata tcaaccaggg ccatcagtcc
     6241 gcgcgtgccg gaacgtatgc cacgacgtta ccagccgggc gcgaaggggt gatcaataaa
     6301 gatattaacg gcgtggtgcg ctgggacttc gcaccattgc aatcgctgga actggaagcg
     6361 ggttacagcc gccagggtaa cctgtatgcg ggcgataccc agaacaccaa ctctgacgct
     6421 tacactcgct cgaaatatgg cgatgaaacc aaccgcctgt atcgccagaa ctacgcgctg
     6481 acctggaacg gtggctggga taacggcgtg accaccagca actgggtgca gtatgaacac
     6541 acccgtaact cgcgtattcc ggaaggtctg gcgggcggta ccgaagggaa atttaacgaa
     6601 aaagcgacac aggatttcgt cgatatcgat ctcgatgacg tgatgctgca cagcgaagtt
     6661 aacctgccga ttgatttcct cgttaaccag acgctgacgc tgggtacgga gtggaatcag
     6721 caacggatga aggacttgag ttccaatacc caggcgctga ccggggcgaa caccggcggc
     6781 gctattgatg gtgtgagtgc caccgaccgt agcccgtatt caaaagcaga aattttctcg
     6841 ctgtttgccg aaaacaacat ggagctgact gacagcacca tcgtaacgcc ggggctgcgt
     6901 ttcgatcatc acagtattgt cggcaataac tggagcccgg cgctgaacat atcgcaaggt
     6961 ttaggcgatg acttcacgct caaaatgggc attgcccgtg cttataaagc accgagcctg
     7021 taccagacta acccgaacta cattctctac agtaaaggtc agggctgcta tgccagcgcg
     7081 ggcggctgct atctgcaagg taacgatgac ctgaaagcag aaaccagcat caacaaagag
     7141 attggtctgg agttcaaacg cgacggctgg ctggcgggcg tcacctggtt ccgtaacgat
     7201 tatcgcaata agattgaagc gggctatgtg gctgtagggc aaaacgcagt cggcaccgat
     7261 ctctatcagt gggataacgt gccgaaagca gtggttgaag gtctggaagg atcgttaaac
     7321 gtaccagtta gcgaaacggt gatgtggacc aataacatca cttatatgct gaagagtgaa
     7381 aacaaaacca cgggcgaccg tttgtcgatc atcccggagt acacgttgaa ctcaacgctg
     7441 agctggcagg cgcgggaaga tttgtcgatg caaacgacct tcacctggta cggtaagcag
     7501 cagccgaaaa aatacaacta caaaggtcag ccagcggttg gcccggaaac caaagaaatc
     7561 agtccttaca gcattgtggg tctgagcgcg acctgggatg tgacgaagaa tgtcagtctg
     7621 accggcggcg tggacaacct gttcgacaaa cgtttgtggc gtgcgggtaa tgcccagacc
     7681 acgggcgatc tggcaggggc caactatatc gcgggtgccg gggcgtatac ctataacgag
     7741 ccgggacgta cgtggtacat gagcgtaaac actcacttct gatgctaacg tcagattgtt
     7801 gacaaagtgc gcgtcgttca tgccggatgc ggcgtgaacg ccttatccgg cctacaaaaa
     7861 tcttgccaat tcaatatatt gcaggaccat gtaggcctga taagcgtagc gcatcaggca
     7921 gtttagcgtt tgtcatcagt ctctaatatg gtcgacatga aaactacgca tacctccctc
     7981 ccctttgccg gacatacgct gcattttgtt gagttcgatc cggcgaattt ttgtgagcag
     8041 gatttactct ggctgccgca ttacgcgcaa ctgcaacacg ctggacggaa gcgcaaagcc
     8101 gaacatttag ccgggcggat cgctgcaatt tatgcgctgc gggaatatgg ctataaatgt
     8161 gtgcccgcaa tcggcgagct acgccaaccg gtgtggcctg cggaggtata cggcagtatt
     8221 agccactgcg gggctacggc attggccgtg gtttcccgtc aaccgattgg cgttgatatc
     8281 gaagaaattt tttctgcgca aacagcgacc gaattgacag acaacattat tacaccagca
     8341 gaacacgagc gactcgcaga ctgcggttta gccttttctc tggcgctgac actggcattt
     8401 tccgccaaag agagcgcatt taaggcaagt gagatccaaa ctgatgcagg ttttctggac
     8461 tatcagataa ttagctggaa taaacagcag gtcatcattc atcgtgagaa tgagatgttt
     8521 gctgtgcact ggcagataaa agaaaaaata gtcataactc tgtgccaaca cgattaattg
     8581 acaacatctg gtacgattcg cccgcagcca tcactgaccg cggacgaaag tgtaaagcag
     8641 gtgccttacc actctgacct gacaaccgga tatgcgggga ttgctccccg cacaacggct
     8701 acttcttcgg ttcgtaagcg agaacagcct taaactcaat attacgttcc tttacggtga
     8761 actcacacag cgagtctccg accagaagcg taaatcccag taccgtcaaa cacagcacta
     8821 tgactgccac aagggcatat ttcgtcagca tgtttatatt gcctccatgc gaagaaggga
     8881 ctaccatccg agttgttgag gctcggagtg gcagccccag gattgataga aatatctcct
     8941 ggggcttcat ctttccagac ctcagagtta acctgaaacc ggaaagcttc aggcacccgc
     9001 cgttatctta cccttcctca acaaaatagc tgtttattta tacagtgaat cctgtttcgg
     9061 acttctgtcg gcaaaactca tcattgctct taaaacgaaa tcgcccgcag ccatcactga
     9121 ccgcgggcga aagtgtaaag caggtgcctt accatcctga cctgacaacc ggatatgcgg
     9181 ggattgctcc ccgcacaacg gctacttctt cggttcgtaa gcgagaacaa ccttaaactc
     9241 aatattacgt tcctttacgg tgaactcaca cagcgaatcc ccgaccagaa gcgtaaatcc
     9301 cagcaccgtt aaacacagca ctatgactgc cgcaagggca tatttcgtca gcatgtttat
     9361 attgcctcca tgcgaagaag ggactaccat ccaaattgtt caggtttggg taggtagccc
     9421 cagggttgat agaaatatcg tcctggggct tcatctttcc agacctcaga gtaaacctga
     9481 aaccggaaag cttcaggcac ccgcagttat cttacccttg cttagcaaaa tagctgttta
     9541 tttatacagt aagtcctgtt tcggacttct cactccccat ttgatcaact gaagctgaac
     9601 ccgttttttt ctgcatgcct caatcgtcaa aattcttcgc caccagccag ccgtgccata
     9661 acttgtcaca ttgcaaaagt agccaaattg cttcagtcac catcaccaaa aaaagaaaca
     9721 ttccagaact tccgcatctc gcccagccgc tccgacttct atactgaata gaaaacgcca
     9781 acttaagaga aacctatgcc attacccgat tttcatgttt ctgaaccttt taccctcggt
     9841 attgaactgg aaatgcaggt ggttaatccg ccgggctatg acttaagcca ggactcttca
     9901 atgctgattg acgcggttaa aaatgagatc acggccggag aggtaaagca cgatatcacc
     9961 gaaagtatgc tggagctggc gacggatgtt tgccgtgata tcaaccaggc tgccgggcag
    10021 ttttcagcga tgcagaaagt cgtattgcag gcagccgcag accatcatct ggaaatttgc
    10081 ggcggtggca cgcacccgtt tcagaaatgg cagcgtcagg aggtatgcga aaacgaacgc
    10141 tatcaacgaa cgctggaaaa ctttggctat ctcatccagc aggcgaccgt ttttggtcag
    10201 catgtccatg ttggctgcgc cagtggcgat gacgccattt atttgctgca cggcctgtca
    10261 cggtttgtgc cgcacttcat cgccctttcc gccgcgtcgc cgtatatgca gggaacggat
    10321 acgcgttttg cctcctcacg accgaatatt ttttccgcct ttcccgataa tggcccgatg
    10381 ccgtgggtca gtaactggca acaatttgaa gccctgtttc gctgcctgag ttacaccacg
    10441 atgatcgaca gcattaaaga tctgcactgg gatattcgcc ctagtcctca ttttggcacg
    10501 gtggaggttc gggtgatgga taccccgtta acccttagcc acgcggtaaa tatggcggga
    10561 ttaattcagg ccaccgccca ctggttactg acggaacgcc cgtttaaaca tcaggagaaa
    10621 gattacctgc tgtataaatt caaccgtttc caggcctgcc gctatgggct ggaaggcgtc
    10681 attaccgatc cgcacactgg cgatcgtcga ccgctaacgg aagatacctt gcgattgctg
    10741 gaaaaaatcg ccccttccgc acataaaatg ggtgcatcga gcgcgattga ggccctgcat
    10801 cgccaggtcg tcagcggtct gaatgaagcg cagctgatgc gcgatttcgt cgccgatggt
    10861 ggctcgctga ttgggctggt gaaaaagcat tgtgagatct gggccggtga ctaagtaggg
    10921 aattgcctta cagaagaata tccctgacaa tggtgtttta acttacattt aacaatgtta
    10981 tgaaacaccc tttagaaacc ttgactaccg cagcaggcat tttgctgatg gctttcctct
    11041 cttgcctgct gctgcccgcc cccgcactga ggctgacgct ggcacaaaaa ctggtgacca
    11101 tgttccatct gatggatctt agccagcttt acactttatt gttttgtctg tggtttttag
    11161 tgctgggcgc tattgagtat tttgttctgc gctttatctg gcgacgctgg ttctcgctgg
    11221 cggattaaac gtcgattatc gccgtacttc gcggcatact ttgcttattc tccttcgcct
    11281 aaaggaacgt ttatggataa gcaatcactg cacgaaacgg cgaaacgcct ggcccttgag
    11341 ttaccctttg tcgagctttg ctggcctttt ggcccggagt tcgatgtttt taaaattggc
    11401 ggcaaaattt ttatgctgtc gtcggagctg cgcggcgtcc cctttatcaa tctgaagtcc
    11461 gatccacaaa aatccctgtt aaatcagcag atatacccga gcattaagcc agggtatcac
    11521 atgaataaaa agcactggat ttcggtgtat cccggcgagg aaatctccga agcgttactt
    11581 cgcgatctga tcaacgattc gtggaatctg gtggttgatg gtctggctaa acgcgatcaa
    11641 aaaagagtgc gtccaggcta aagcggaaat ctatagcgca tttttctcgc ttaccatttc
    11701 tcgttgaacc ttgtaatctg ctggcacgca aaattacttt cacatggagt ctttatggat
    11761 atcatttctg tcgccttaaa gcgtcattcc actaaggcat ttgatgccag taaaaaactt
    11821 accccggaac aggccgagca gatcaaaact ctcctgcaat acagcccatc cagcaccaac
    11881 tcccagccgt ggcattttat tgttgccagc acggaagaag gtaaagcgcg tgttgccaaa
    11941 tccgctgccg gtaattatgt gttcaacgaa cgtaaaatac ttgatgcctc gcacgtcgtg
    12001 gtgttctgtg caaaaaccgc gatggacgat gcctggctga agctggttgt tgaccaggaa
    12061 gatgctgatg gccgctttgc cacgccggaa gcgaaagccg cgaacgataa aggtcgcaag
    12121 ttcttcgctg atatgcaccg taaagatctg catgatgatg cagagtggat ggcaaaacag
    12181 gtttatctca acgtcggtaa cttcctgctc ggcgtggcgg cgctgggtct ggacgcggta
    12241 cccatcgaag gttttgacgc cgccatcctc gatgcagaat ttggtctgaa agagaaaggc
    12301 tacaccagtc tggtggttgt tccggtaggt catcacagcg ttgaagattt taacgctacg
    12361 ctgccgaaat ctcgtctgcc gcaaaacata accttaaccg aagtgtaatt ctctcttgcc
    12421 gggcatctgc ccggctattt cccctcagat tctcctgatt tgcataaccc tgtttcagcc
    12481 gtcatcatag gctgctgttg tataaaggag acgttatgca ggatttaata tcccaggttg
    12541 aagatttagc gggtattgag atcgatcaca ccacctcgat ggtgatgatt ttcggtatta
    12601 tttttctgac cgccgtcgtg gtgcatatta ttttgcattg ggtggtactg cggaccttcg
    12661 aaaaacgtgc catcgccagt tcacggcttt ggttgcaaat cattacccag aataaactct
    12721 tccaccgttt agcttttacc ctgcagggga ttatcgtcaa tattcaggcg gtattctggc
    12781 tgcaaaaagg caccgaagcg gcagatattc tgactacctg cgcgcagttg tggatcatga
    12841 tgtatgcgct gctttcagtc ttctcgttgc tggatgtgat tttgaatctg gcgcagaaat
    12901 tcccggcggc atctcagtta ccgctgaaag ggatatttca ggggattaaa ctgatcggcg
    12961 cgattctggt cggcattttg atgatctcgc tgctgattgg tcagtcgcca gcgattctga
    13021 tcagcggtct tggtgcaatg gctgccgtgc tgatgttggt ttttaaagat ccgattcttg
    13081 gtctggtggc aggtattcag ctttccgcga acgatatgct gaaactgggc gactggctgg
    13141 agatgccgaa atacggcgcg gatggcgcgg tgatcgatat tgggttaacc accgtcaaag
    13201 tgcgtaactg ggacaatacc attaccacta ttcccacctg gtctctggtt tctgactcct
    13261 ttaaaaactg gagcgggatg tcagcatctg gcgggcgacg tattaagcgc agtatcagta
    13321 ttgatgtcac cagtattcgt tttcttgatg aagacgaaat gcaacgtctg aataaagcgc
    13381 atttgttaaa gccttattta accagccgcc atcaggaaat taatgagtgg aatcgccagc
    13441 aaggttctac ggagtcgata ttaaacctgc gccgaatgac caatattgga acctttcgtg
    13501 cctatctgaa cgaatatctg cgtaaccatc cgcggattcg taaagatatg actttaatgg
    13561 tacgccaact ggctccaggt gataacggtt taccgctcga gatctatgcg tttaccaaca
    13621 ccgtggtgtg gctggaatat gaaagcattc aggctgatat attcgatcac atatttgcga
    13681 ttgtcgaaga gtttggtctg cgacttcatc agtcgccaac cggcaatgat attcgctctc
    13741 tggcgggtgc atttaagcag taattaaaaa aaccgctctc atcgaatgga tgagagcgga
    13801 catcgttttg tcggatgtag cgtgaatgcc ttatttccga cgcagcgttt taaatgccac
    13861 aaacaggaat acaatccaca ccggcagcag gatcgctgac aagcgcatat catccatcgt
    13921 gcacatcagc agcaaaatca tgccgaggaa ggcaatgcaa agatagttgc cgaacggata
    13981 gagcagcgcc ttaaactgtg tttcacgccc ctgacgtcgc atcgctgcac gaaaacgcag
    14041 atgcgccaga cagatcataa tccagttcaa cagcagcgtt gctaccacca gcgccatcag
    14101 cagaccaaac gctttttgcg gcagcagata gttgattaac accaccagcg aagtgatcgc
    14161 tccggaaagc atcagcgagt taatcggcac accgcgacgg ctgacgcgag tcaaaaactt
    14221 cggcgcatta ccctgcacag aaaggccaaa cagcatgcgg ctgttagagt aaaccccgct
    14281 gttatacact gacagcgatg ctaccagaat gacgaagttc agcgcagaag ctaccacgtt
    14341 gctgtcgaga ttatggaaaa tcatcacaaa cgggctactg ttggatttca cttccaccca
    14401 cggatagagc gccagtaaaa ccaccagtga accgatgtaa aacagcagga tgcgatacac
    14461 cacctgattt accgcttttg gaatgctttt ttccggatcg cgcgcttcag cggcagtaat
    14521 cccaatcagc tccagaccgc cgaaggagaa cataattacc gccagcgaca aaatcagccc
    14581 attccagccg gtggcgaaga aaccaccgta gcgccagagg ttgtcgatac tggctttctc
    14641 gccgccgtga ccagaaaaca gcagccacag gccaaagcca atcataccga tgatcgccag
    14701 cactttaatc aacgcaaacc agaactcggt ttcgccatat aagcgcacgt tcaccaggtt
    14761 aacggcgttg atgataataa agaaggcggc agcccaaatc cacgttggaa catccgggaa
    14821 ccagtactgc atatagatgc ccgcagcggt cagctctgcc atccccacca gcacgaacat
    14881 cacccagtag ttccagccag agaggaagcc cgcgaacggt ccccagtatt tataggcaaa
    14941 gtgggcaaac gaaccggata ccggctcttc gaccaccatc tcgccgagct ggcgcataat
    15001 caggaaagcg atgatcccgg cgacgccgta gcccagcaat acagccggac ccgccatctg
    15061 aatcgccggg ccaatgccaa gaaacagacc agtaccaatt gcgccaccca gcgcaatcag
    15121 ttgaatatga cggttatgta atccgcgatg aagcgtcggc tcttgattcg acgcagtatc
    15181 ttccgatacg gttgacgcgt ttttcacgcc tttcccctgt gtgtcttttt tgttgagggg
    15241 caccttttaa catttagtgc ccatcgtcgc aagacacaat ccacacggtt aaacggggta
    15301 tcctgctttt atttccgtac ccgatgtcgg tgcagccaca tcagcttata cgccgccggg
    15361 ataataaaca gcgacagcaa aggtgcggtg atcatgccgc caatcatcgg tgcggcaatc
    15421 cggctcatca cctctgaacc agcccccgtt ccccacagaa tcggcagcag accggcgata
    15481 atcaccgcca ccgtcatcgc tttcgggcgc acgcgcagta ccgcgccgtg atacaacgcc
    15541 tcatccagct tctgctcact gaatgtttgc ggattattca acgacggctc ggcctctatg
    15601 gcgtgacgta aatacatcag catcaccacg ccaaattcgg cggcgacccc ggcaagggca
    15661 ataaagccag tacccgtcgc cacagaaaga tgaaagccca tccaccacag caaccagatg
    15721 ccgcccacca gcgcaaacgg tacgctgctg ataatcagca acgcttcgcc cacccgacgg
    15781 aatgccagat acaacagcac gaagatgatc atcagtgtca tcggcaccat gagtttcagc
    15841 ttatggttgg cgcgctccag tagctcgaac tgcccggaga atgccacgct ggtgcccggt
    15901 tttaactgca ctttttcagc tatcgctttt tgcaaatcgt gaaccaccga caccatgtca
    15961 cgatcgcggg catcgatata aatccagctc gtcgggcgcg cattctcggt tttcagcatc
    16021 gacggtccgg tagagacttt aacgtcggcc acgtctgcca gggtgatttg ctgcttcatc
    16081 ggcgtcagga tcggcaactg gcgcagtgcc tgcggactat cgcgccagct ttgcggataa
    16141 cgcagattaa tgggataacg ggcaatccct tccaccgttt cgccaaccat cgccccgccc
    16201 accgcagaag tcacaaacaa ctgcacatcc gccaccgtca taccgtaacg cgcggctttt
    16261 tcacggttaa tctcaacgtt gatatagcgc ccaccttcca gacgctcggc aagcgcagaa
    16321 gccacgcctg gtaccgttcg tgccacctct tcaatttgct ccgccatcgc gtcgatatcc
    16381 gccagcacag tgccggaaac tttaatgccg atggggcttt taatgccagt cgagagcata
    16441 tcgatacggt tacgaattgg cggcacccac agattcgcca gccccggcag ccgcacggtg
    16501 ttatccagtt cctcaatgat tttgtccatc gtcatgccag gccgccactg atcctgcggc
    16561 ttaagctgga tggtcgtttc taccatctcc agcggagcag aatcggtggc ggtttccgct
    16621 ttcccggttt tgccaaatac ccgcgccact tcaggtacgc tcataattag cttgtcggtt
    16681 ttttgcagca tactcgccgc ctctgctgcg gaaatccccg gcagcgtcga tggcatatac
    16741 aacaagtcgc cttcattgat ctgcggtaaa aattccccgc caactttatt gagcggccag
    16801 agaaccgtca gcaccgaaag cgctgtcacc agcagcgtgg ttttcggcca gtgcagtact
    16861 ttcagcaaca gcggatgata aacacgaatc aaaaagcgat tgagcgggtt actgctttcc
    16921 ggcggaattt tgccacggat ccagtacccc atcaggatag ggatcactac gatcgccagc
    16981 agcgccgcgc ccgccatcgc ataggtttta gtgaacgcca acgggccaaa cagacgccct
    17041 tcctgccctt ccagggtgaa gatcgggata aacgacaacg tgataatcag cagactgata
    17101 aatagcgccg gacccacttc aacagatgca tcggtgatca cctgccagcg cgttttatta
    17161 tccagcgtgg cgtcaggatg ctggtgctgc cactcttcca gccgtttatg tgcattttcg
    17221 atcatgacga tagcggcatc gaccatcgcc ccgacggcaa tcgcaatgcc gcccaacgac
    17281 ataatattgg cattcagtcc ctggaagtac atgacaataa aagcaataca caaccccagc
    17341 ggcaacgaaa taatcgccac cagcgccgag cgcacatgcc agagaaacag cgcacagact
    17401 accgccacca caataaactc ttccagcaac ttgccgctga ggttgtcgat ggcgcggtca
    17461 atgagctggc tgcgatcgta tgttgtaact atctccatgc cttccggcag actacttttc
    17521 agcgtttcca gtttgtcctt cacggcggcg atcacttctc gggcgttttt gccggatcgc
    17581 aggatcacca ccccgcccgc cacttcgcct tcgccgttta gttcggcaat gccccggcgc
    17641 atctccgggc caatctggac cttcgcaaca tcgcgcagat aaacgggcac gccattttca
    17701 ctggctttta aaacgatgtg attaaagtcg tcgagcgttt gcagatagcc gctggcgcgc
    17761 accatatatt ccgcttccgc cagttcgatc gacgaaccgc ccgcttcctg gtttgaagca
    17821 tccagcgcgc tttttacttc ggcgagactg atgccatact gcgccaggcg ctggggatcg
    17881 ataaccacct gatactcttt caccacaccg cccaccgacg ccacttccgc aacgtcaggg
    17941 atggttttca gctcatattt gagaaaccag tcctgcaatg agcgtaaatc ggccagatcg
    18001 tgcttaccgc tgcgatccac cagtgcatat tcatagatcc agccaacacc cgtggcatct
    18061 ggtcccagct cggcgctgac tcccgcaggc agcttaccct gtacctggtt gaggtactcc
    18121 agcacccgcg aacgcgccca gtacggatcg gtgccatctt cgaaaatgac atacacataa
    18181 gagtcgccaa actgtgagaa accgcgcaca gtcttcgcgc caggcaccga caacatggtg
    18241 gtggttagcg gataagtcac ctgattttca acgatttgtg gtgcctgacc gggatagctg
    18301 gttttaataa taacctgcac atcggagaga tccggcagcg catccactgg cgtattaatg
    18361 atggtccagg tgccccagat gctcagaaac aacgcgccca tcagcaccaa aaaacggttc
    18421 gccaccgagc gacgaataat ccattcaatc attggttatt ccctcaatgc gcatgggtag
    18481 cactttcaga gcgcatccgc tccagtgcgc cagaaatatt ggcttcggaa tcaatcagga
    18541 acaggccgct ggaaaccacc ttttcacctt ccgccagacc agagcgtaat gcggtgacgc
    18601 cttgcgatgc ctggaaaaca gcaacgcgtt tcggtacaaa gcgcccgtcg gcatcaacgg
    18661 taatcacccg ctgttcgctg ccggtatcaa tcagcgcttg tgacggaatg agcagcatcg
    18721 gttcgctggc ggtgttgagt tgcaaccagg cgttcatgcc cggttttagc gcctcgtcgg
    18781 cgttgtcgac ttccagacgc agctgcagcg tgcgggtcgc ggcatccacg ccaggtagca
    18841 gcgtccattt gcggatggtg agtgttttat ccggtcgcgc cggaacggtg agggtaaact
    18901 gcgaggcatc tttcaccagc caggcgatgg actccgggat cgcagcagtg acccacaccg
    18961 ggtccatacc ctgaattttc gcgaccacgt tatctttggc gatattcatt cccgcgcgca
    19021 gatcaaacgc ggtgatcacg ccatcaatgg gcgctttgag cgtaaagcga gtctggattt
    19081 tttgcgtggc gatcaggcgg cgaatatccg cctccggcat tcccgccagt cgcagccgct
    19141 caagaatgcc ttcagtctgg gtcgccgtac cgccggtttc gcgcagcagt aaatactcag
    19201 tctgcgcttc cacccagtca ggaatggtca ggtcgagaag cggtgtgccc ttttgtactt
    19261 tatcgcccac ggtaagcgga tacaccttgt cgataaaccc ggcagcgcga gcctgcacaa
    19321 tggcatactg atactcgttg taactgacat tcgccgggaa actctgggca aaagtcagcg
    19381 gtccgcgcgt gacggtagcc gttttcaccc ccagattctg cgtctgagtc gggtcaatgc
    19441 gcacaccaga cgcagaactc tcttcatcgg catatttcgg caccagatcc atatccataa
    19501 acggcgattt acctggttta tcgaaccgcg tattgggata catcgggtcg taccagaata
    19561 agattttacg ttctgcggtc gacgtttttt ctgcaggcgg ttccgccttt gcaacccagg
    19621 taaaacctgc cgcagaaata ataccgcccg cgatcatgct gccgataata agcgcgattt
    19681 ttttcatctc attaaacctg ggttactggc tgactttaat atcctgtaat aaagaaaggt
    19741 tgccctgctg gacaaaatta aacgccactt tgtcgccagt tttaatttca ctcattttcg
    19801 tctgcggagt gatggtaaag cgcatggtca tctccggcca gttcacggca gcaatcggat
    19861 cgtgatggat ggtgattttt ttgctttcca gatcaatacc ctttaccacg ccagtggcgc
    19921 taataacctg cggttgtact tcgctcatgg tttcatgatg atgttcgtta gcctgggcat
    19981 taaagccaat aacggtaaac agactgaaca ttgcgacttg cagtgctttt ttcatttatt
    20041 ctctcctgga gttaaaagtt attgctgcca accgccacca agtgcggtat ataaagaaat
    20101 ttcgttaacc tgacgggcat aattcaggtc aagtaaagtt tgtcgggttg caaataacga
    20161 acgttcggca tccagcactt ccagataact tactgcgccg tgctgatata atgcccgcgc
    20221 ccgttgcaaa gtaatttgca gcgatgccag ataacgctgc tgggcgctaa tttgatcgtt
    20281 caggctttga cgtaatgcca gcgcatctgc cacttcttta aaggcgttct ggattttctg
    20341 ttcataattc actaccgact gctgctggcg aatttcggcg atatccagat tggcctggtt
    20401 gcgtccggca ttaaaaatgg ggatctcaat tttaggaata aaattccaca tcccgctgct
    20461 ggcgttaaat aatgacgaca gatcgctgct ggcggttgat attccgctgg tcaggcttat
    20521 agatgggaaa aatgccgcgc gtgcggcccc aatattggca ttagccgcca ttaacgcgtg
    20581 ttcagcttcc ataatatccg ggcgctgcaa taagatttgc gacgacaagc ccgccggtaa
    20641 tttaacgctt tgcaggctgt cgctgtttac tgtctgcgct tgcggcagct tgccgtagct
    20701 tcccagcaac agttgcaatg cattattcgc ctgcgccagt tccccctgac gtttagcgat
    20761 gtcgctgcgg gtactttcta tcaccccgcg agcctgttcc agcgccagaa cattactgct
    20821 acctgtcaac agttgttttt cgacaaacgc atatgactgc tgataattac gcagcgtttc
    20881 ttcagctatt tgcaattgcg catacgccag ttgctgattg aaatagcttt gcgcgacatt
    20941 agaaaccagc agaatatgca ccgcgcgctg agcttcctca gtggctaaat aattttggcg
    21001 ctcggcttcg ctcatgttct ttaagcgacc gaaaaaatcg aggtcaaagc tggcgttaag
    21061 gccggtcgaa aactcccgtg tcgtggcggt attcccttta agattaccgc tccagctgcc
    21121 gctgccctcg ccattgagct gtgggtagcg gtcggcatcg gtcagacgat attgcgcccg
    21181 tgcctcctgc actttcagcg tcgccatgcg caaatcccgg ttattcacca gcgcctcgct
    21241 aatcagcgtc ttcacctgat tatcaacaaa aaaggtgcgc cagcccgcgt tctgatagtt
    21301 atctgctgcg ttaacgaggc cgttctggct gagtgagaac tgctgcggta cgggcattgc
    21361 cgggcgctga taatccggtg ccagtgaaca accggttagc gcaagggcca cacaaaatgg
    21421 cagaagttta caaggagaca taggctcata atttctgatg attttatgcc gccaacttta
    21481 ctcgccaggc tctgattttc cggtgacagg aaaatgacaa aattgtcatt ttgccaataa
    21541 gcgattgcca tctgatcccg ctactctaga attgcccggg caacatgcgg aggaaatatg
    21601 aaactgttga ttgtcgaaga tgaaaagaaa accggagaat acttgaccaa agggttaacc
    21661 gaagccggtt ttgtggtcga tttggccgac aacgggctga atggctacca tctggcgatg
    21721 accggtgatt atgatctgat aatcctcgat attatgctgc cggacgtgaa cggctgggat
    21781 atcgtgcgca tgttacgctc cgccaataaa gggatgccga ttctgttgct taccgcgctt
    21841 ggcaccattg aacatcgcgt caaggggctg gagttggggg cagatgacta cctgatgaaa
    21901 ccattcgctt ttgctgaact gctggcgcgg gtgcgcactc tcctgcggcg cggggcggcg
    21961 gtaattatcg aaagtcagtt tcaggttgcc gacctgatgg tcgatctcgt cagccgcaaa
    22021 gtcacccgca gcggcacgcg catcactttg accagtaaag agtttactct gctggagttt
    22081 tttctccgcc atcagggcga agtgctgccc cgctcgctta tcgcctcgca ggtgtgggac
    22141 atgaatttcg acagcgacac taacgccatt gatgtggcgg tgaagcggct acgcggcaaa
    22201 atcgacaacg actttgagcc gaagctgatt cagaccgtgc gcggcgtggg ctatatgctt
    22261 gaggtgccgg atggtcagta agccatttca gcgcccgttt tcgctggcaa cccgtctgac
    22321 cttttttatc agcctggcca ccatcgcggc gtttttcgcc tttgcatgga tcatgatcca
    22381 ctcagtgaaa gtgcattttg ccgagcagga tattaatgat ttaaaagaaa ttagcgccac
    22441 ccttgaacgg gtacttaatc atcctgacga gacgcaagcc cgacgcttaa tgacgctgga
    22501 agatatcgtc agtggttatt ccaacgtgtt gatttccctg gcagatagcc acggcaaaac
    22561 ggtgtatcac tcccccggtg cgccggatat ccgcgagttt acgcgtgacg ccatacccga
    22621 taaagacgcg cggggcggtg aggtgtatct cctttccggc ccgacgatga tgatgccagg
    22681 ccacggtcac gggcatatgg aacacagcaa ctggcggatg attaacttgc cggttggccc
    22741 gttggtggac ggcaaaccga tttatacgct ctacatcgcg ctttcgatcg attttcatct
    22801 tcattacata aatgatttga tgaataaact tattatgacc gcatctgtca tcagcatcct
    22861 gatcgtcttt atcgtgctat tggcggtaca taaaggtcac gcgccgatcc gcagcgtcag
    22921 ccgtcaaatc cagaatatca cctcgaaaga tctcgacgtt cgccttgacc cgcagaccgt
    22981 gcccattgag ctggaacagc tggtactgtc gttcaaccat atgatcgagc gtattgagga
    23041 tgtctttacc cgccagtcca atttctcagc ggatatcgct cacgaaattc gcacgccgat
    23101 taccaatctc atcacgcaaa cggaaatcgc cctcagccag tctcgcagcc agaaggagct
    23161 ggaagatgtg ctctactcta atctcgaaga gctgacgcga atggcgaaaa tggtcagcga
    23221 tatgctgttt ctcgctcagg ccgataacaa ccagctaatc cccgaaaaga aaatgctcaa
    23281 cctggcggat gaagtcggca aagtgttcga ttttttcgag gcgttagcgg aagatcgcgg
    23341 cgtggagttg cggtttgttg gcgacaaatg tcaggttgcg ggcgatccgc tgatgctgcg
    23401 tcgggcgtta agcaacctgc tttctaatgc cctgcgttat acgccaccca gtgaggctat
    23461 tgtagtgcgc tgccagacgg tcaatcatca ggtgcaagtt tccgtcgaaa accccggtac
    23521 gcccattgcg cccgagcact taccgcgatt gtttgaccgt ttctatcgcg ttgacccttc
    23581 ccgccagcga aaaggtgaag gtagcggtat tgggctggcg atagtgaaat cgattgttgt
    23641 cgcgcataaa ggcacggttg cggtaacgtc agatgcgcgg gggacaaggt ttgtgattat
    23701 gctgccggag agagagtgat tattaagttc aaattcaggg cgtggtgcat cacctcctgg
    23761 tattgttgat caacaaatta gagaaaaact tattaaacat atgaaatatc gaaggctttt
    23821 atttttcaaa gtttcacgag atgtttgtat atgaaactta gttaaatctg tgtttcttcc
    23881 aattgtagat cacaatgccc tttctaaatt ttcatcgtta taaacaagcc atctatcata
    23941 t
//
LOCUS       DAPGUL010000070        23359 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.071, whole genome shotgun sequence.
ACCESSION   DAPGUL010000070 DAPGUL010000000
VERSION     DAPGUL010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23359)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23359)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23359
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.071"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            167..676
                     /gene="sulA"
                     /locus_tag="RHX21_002918"
     CDS             167..676
                     /gene="sulA"
                     /locus_tag="RHX21_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibitor SulA"
                     /protein_id="HDV1988071.1"
                     /translation="MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPM
                     MTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVQASGLPLTKVMQISQLSPCHTVES
                     MVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSG
                     LKIHSNLYH"
     gene            1033..2085
                     /gene="ompA"
                     /locus_tag="RHX21_002919"
     CDS             1033..2085
                     /gene="ompA"
                     /locus_tag="RHX21_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706879.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpA"
                     /protein_id="HDV1988072.1"
                     /translation="MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGF
                     IPNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGDNINGAYKAQGVQLTA
                     KLGYPITDDLDVYTRLGGMVWRADTKANVPGGASFKDHDTGVSPVFAGGVEYAITPEI
                     ATRLEYQWTNNIGDANTIGTRPDNGLLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKH
                     FTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQG
                     LSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRV
                     EIEVKGIKDVVTQPQA"
     gene            complement(2160..2612)
                     /gene="matP"
                     /locus_tag="RHX21_002920"
     CDS             complement(2160..2612)
                     /gene="matP"
                     /locus_tag="RHX21_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrodomain Ter protein MatP"
                     /protein_id="HDV1988073.1"
                     /translation="MKYQQLENLESGWKWKYLVKKHREGELITRYIEASAAQEAVDVL
                     LSLENEPVLVNGWIDKHMNPELVNRMKQTIRARRKRHFNAEHQHTRKKSIDLEFIVWQ
                     RLAGLAQRRGKTLSETIVQLIEDAENKEKYANKMSSLKHDLQALLGKE"
     gene            2798..4558
                     /locus_tag="RHX21_002921"
     CDS             2798..4558
                     /locus_tag="RHX21_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lon protease family protein"
                     /protein_id="HDV1988074.1"
                     /translation="MTITKLAWRDLVPDTDSYQEIFAQPHLIDENDPLFSDTQPRLQF
                     ALEQLLHTRASSSFMLAKAPEESEYLNLIANAARTLQSDAGQLVGGHYEVSGHSIRLR
                     HAVSADDNFATLTQVVAADWVEAEQLFGCLRQFNGDITLQPGLVHQANGGILIISLRT
                     LLAQPLLWMRLKNIVNRERFDWVAFDESRPLPVSVPSMPLKLKVILVGERESLADFQE
                     MEPELSEQAIYSEFEDTLQIVDAESVTQWCRWVTFTARHNHLPAPGADAWPVLIREAA
                     RYTGEQETLPLSPQWILRQCKEVASLCDGDTFSGEQLNLMLQQREWREGFLAERMQDE
                     ILQEQILIETEGERIGQINALSVIEFPGHPRAFGEPSRISCVVHIGDGEFTDIERKAE
                     LGGNIHAKGMMIMQAFLMSELQLEQQIPFSASLTFEQSYSEVDGDSASMAELCALISA
                     LADVPVNQSIAITGSVDQFGRAQPVGGLNEKIEGFFAICQQRELTGKQGVIIPTANVR
                     HLSLHSELVKAVEEGKFTIWAVDDVTDALPLLLNLVWDGEGQTTLMQTIQERIAQASQ
                     QEGRHRFPWPLRWLNWFIPN"
     gene            4627..5145
                     /gene="fabA"
                     /locus_tag="RHX21_002922"
     CDS             4627..5145
                     /gene="fabA"
                     /locus_tag="RHX21_002922"
                     /EC_number="4.2.1.59"
                     /EC_number="5.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014915875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-hydroxydecanoyl-ACP
                     dehydratase/trans-2-decenoyl-ACP isomerase"
                     /protein_id="HDV1988075.1"
                     /translation="MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMT
                     ETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEG
                     KGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTASD
                     LKVGLFQDTSAF"
     gene            complement(5215..5382)
                     /gene="rmf"
                     /locus_tag="RHX21_002923"
     CDS             complement(5215..5382)
                     /gene="rmf"
                     /locus_tag="RHX21_002923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome modulation factor"
                     /protein_id="HDV1988076.1"
                     /translation="MKRQKRDRLERAHQRGYQAGIAGRSKEMCPYQTLNQRSQWLGGW
                     REAMADRVVMA"
     gene            complement(5638..6201)
                     /gene="pqiC"
                     /locus_tag="RHX21_002924"
     CDS             complement(5638..6201)
                     /gene="pqiC"
                     /locus_tag="RHX21_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity-associated transporter
                     subunit PqiC"
                     /protein_id="HDV1988077.1"
                     /translation="MKKWLVTIAALWLVGCSSGEINKNYYQLPVVQSGTQSTASQGNR
                     LLWVEQVTVPDYLAGNGVVYQTSDVKYVIANNNLWASPLDQQLRNTLVANLSTQLPGW
                     VVASQPLGSAQDTLNVTVTEFNGRYDGKVIVSGEWLLNHQGQLIKRPFRLEGVQTQDG
                     YDEMVKVLAGVWSQEAASIAQEIKRLP"
     gene            complement(6198..7838)
                     /gene="pqiB"
                     /locus_tag="RHX21_002925"
     CDS             complement(6198..7838)
                     /gene="pqiB"
                     /locus_tag="RHX21_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intermembrane transport protein PqiB"
                     /protein_id="HDV1988078.1"
                     /translation="MESNNGEAKIQKVKNWSPVWIFPIVTALIGAWVLFYHYSHQGPE
                     VTLITANAEGIEGGKTTIKSRSVDVGVVESATLADDLTHVEIKARLNSGMEKLLHKDT
                     VFWVVKPQIGREGISGLGTLLSGVYIELQPGAKGSKMDKYDLLDSPPLAPPDAKGIRV
                     ILDSKKAGQLSPGDPVLFRGYRVGSVETSTFDTQKRNISYQLFINAPYDRLVTNNVRF
                     WKDSGIAVDLTSAGMRVEMGSLTTLLSGGVSFDVPEGLDLGQPVAPKTAFVLYDDQKS
                     IQDSLYTDHIDYLMFFKDSVRGLQPGAPVEFRGIRLGTVSKVPFFAPNMRQTFNDDYR
                     IPVLIRIEPERLKMQLGENADVVEHLGELLKRGLRGSLKTGNLVTGALYVDLDFYPNT
                     PAITGIREFNGYQIIPTVSGGLAQIQQRLMEALDKINKLPLNPMIEQATSTLSESQRT
                     MKNLQTTLDSMNKILASQSMQQLPTDMQSTLRELNRSMQGFQPGSAAYNKMVADMQRL
                     DQVLRELQPVLKTLNEKSNALVFEAKDKKDPEPKRAKQ"
     gene            complement(7843..9096)
                     /gene="pqiA"
                     /locus_tag="RHX21_002926"
     CDS             complement(7843..9096)
                     /gene="pqiA"
                     /locus_tag="RHX21_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity-associated transporter
                     subunit PqiA"
                     /protein_id="HDV1988079.1"
                     /translation="MCEHHHAAKHILCSQCDMLVALPRLEHGQKAACPRCGTTLTVAW
                     DAPRQRPTAYALAALFMLLLSNLFPFVNMNVAGVTSEITLLEIPGVLFSEDYASLGTF
                     FLLFVQLVPAFCLITILLLVNRAELPVRLKEQLARVLFQLKTWGMAEIFLAGVLVSFV
                     KLMAYGSIGVGSSFLPWCLFCVLQLRAFQCVDRRWLWDDIAPMPELRQPLKPGVTGIR
                     QGLRSCSCCTAILPADEPVCPRCSTKGYVRRRNSLQWTLALLVTSIMLYLPANILPIM
                     VTDLLGSKMPSTILAGVILLWSEGSYPVAAVIFLASIMVPTLKMIAIAWLCWDAKGHG
                     KRDSERMHLIYEVVEFVGRWSMIDVFVIAVLSALVRMGGLMSIYPAMGALMFALVVIM
                     TMFSAMTFDPRLSWDRQPESEHEES"
     gene            complement(9226..11133)
                     /locus_tag="RHX21_002927"
     CDS             complement(9226..11133)
                     /locus_tag="RHX21_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDV1988080.1"
                     /translation="MSLISMHGAWLSFSDAPLLDNAELHIEDNERVCLVGRNGAGKST
                     LMKILNREQGLDDGRIIYEQDLIVARLQQDPPRNVEGSVYDFVAEGIEEQAEYLKRYH
                     DISRLVMNDPSEKNLNELAKVQEQLDHHNLWQLENRINEVLAQLGLDPNVALSSLSGG
                     WLRKAALGRALVSNPRVLLLDEPTNHLDIETIDWLEGFLKTFNGTIIFISHDRSFIRN
                     MATRIVDLDRGKLVTYPGNYDQYLQEKEEALRVEELQNAEFDRKLAQEEVWIRQGIKA
                     RRTRNEGRVRALKAMRRERGERREVMGTAKMQVEEASRSGKIVFEMEDVCYQVDGKQL
                     VKDFSAQVLRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHVGTKLEVAYFDQHRA
                     ELDPDKTVMDNLAEGKQEVMVNGKPRHVLGYLQDFLFHPKRAMTPVRALSGGERNRLL
                     LARLFLKPSNLLILDEPTNDLDVETLELLEELIDSYQGTVLLVSHDRQFVDNTVTECW
                     IFEGGGKIGRYVGGYHDARGQQEQYVALKQPAVKKSEEAAVPKAETVKRSSSKLSYKL
                     QRELEQLPQLLEDLEAKLEALQTQVADASFFSQPHEQTQKVLADMAAAEQELEQAFER
                     WEYLEALKNGG"
     gene            complement(11145..13253)
                     /gene="rlmKL"
                     /locus_tag="RHX21_002928"
     CDS             complement(11145..13253)
                     /gene="rlmKL"
                     /locus_tag="RHX21_002928"
                     /EC_number="2.1.1.173"
                     /EC_number="2.1.1.264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 23S rRNA
                     (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA
                     (guanine(2445)-N(2))-methyltransferase RlmL"
                     /protein_id="HDV1988081.1"
                     /translation="MNSLFASTARGLEELLKTELENLGAVECQVVQGGVHFKGDTRLV
                     YQSLMWSRLASRIMLPLGECKVYSDLDLYLGVQAINWTEMFNPGATFAVHFSGLNDTI
                     RNSQYGAMKVKDAIVDAFTRKNLPRPNVDRDAPDIRVNVWLHKETASIALDLSGDGLH
                     LRGYRDRAGIAPIKETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMLATDRAPGL
                     HRGRWGFSGWAQHDEAIWQEVKAEAQTRARKGLAEYSSHFYGSDSDARVIQRARTNAR
                     LAGIGELITFEVKDVAQLTNPLPKGPYGTVLSNPPYGERLDSEPALIALHSLLGRIMK
                     NQFGGWNLSLFSASPDLLSCLQLRADKQYKAKNGPLDCVQKNYHVAESTPDSKPAMVA
                     EDYANRLRKNLKKFEKWARQEGIECYRLYDADLPEYNVAVDRYADWVVVQEYAPPKTI
                     DAHKARQRLFDIIAATISVLGIAPNKLVLKTRERQKGKNQYQKLGEKGEFLEVTEYNA
                     HLWVNLTDYLDTGLFLDHRIARRMLGQMSKGKDFLNLFSYTGSATVHAGLGGARSTTT
                     VDMSRTYLEWAERNLRLNGLTGRAHRLIQADCLAWLREANEQFDLIFIDPPTFSNSKR
                     MEDAFDVQRDHLALMKDLKRLLRAGGTIMFSNNKRGFRMDLDGLAKLGLKAQEITQKT
                     LSQDFARNRQIHNCWLITAA"
     gene            13497..14606
                     /gene="ycbX"
                     /locus_tag="RHX21_002929"
     CDS             13497..14606
                     /gene="ycbX"
                     /locus_tag="RHX21_002929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-N-hydroxylaminopurine resistance protein YcbX"
                     /protein_id="HDV1988082.1"
                     /translation="MATLTRLFIHPVKSMRGIGLTHALADDSGLAFDRIFMITEPDGT
                     FITARQFPQMVRFTPSPVHDGLHLTAPDGSSAYVRFADFATQDAPTEVWGTHFTARIA
                     PDAINKWLSGFFSREVQLRWVGPQMTRRVKRHNTVPLSFADGYPYLLANEASLRDLQQ
                     RCPASVKMEQFRPNLVVSGASAWEEDRWKVIRIGDVVFDVVKPCSRCIFTTVSPEKGQ
                     KHPAGEPLKTLQSFRTAQDNGDVDFGQNLIARNSGVIRVGDEVEILATAPAKIYGAAA
                     ADDTANITQQPDANVDIDWQGQAFRGNNQQVLLEQLENQGIRIPYSCRAGICGSCRVQ
                     LLEGEVTPLKKSAMGDDGTILCCSCVPKTALKLTR"
     gene            complement(14603..15145)
                     /gene="zapC"
                     /locus_tag="RHX21_002930"
     CDS             complement(14603..15145)
                     /gene="zapC"
                     /locus_tag="RHX21_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309057.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapC"
                     /protein_id="HDV1988083.1"
                     /translation="MRIKPDDNWRWYYDEEHDRMMLDLANGMLFRSRFARKMLTPDAF
                     NPSGFCVDDAALYFSFEEKCRDLPLSKEQKAELVLNALVAIRYLKPQMPKSWHFVSHG
                     EMWVPMQGDAACVWLSDTNEQVNLLVVESGENAALCLLAQPCVVIAGRAMQLGDAIKI
                     MNDRLKPQVNVDSFSLEQAV"
     gene            complement(15319..16329)
                     /gene="pyrD"
                     /locus_tag="RHX21_002931"
     CDS             complement(15319..16329)
                     /gene="pyrD"
                     /locus_tag="RHX21_002931"
                     /EC_number="1.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent dihydroorotate dehydrogenase"
                     /protein_id="HDV1988084.1"
                     /translation="MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPFEALVRQKVPA
                     KPVNCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSIEIGTVTPRPQPGNDKPRLFR
                     LVDAEGLINRMGFNNLGVDNLIENVKKAHYDGVLGINIGKNKDTPVEQGKDDYLICMD
                     KIYPYAGYIAINISSPNTPGLRTLQYGEALDDLLIAIKNKQNDLQKIHQKYVPIAVKI
                     APDLSEEELIQVADSLVRHNIDGVIATNTTLDRSLVQGMKNCDQTGGLSGRPLQLKST
                     EIIRRLSQELNGRLPIIGVGGIDSVIAAREKIAAGATLVQIYSGFIFKGPPLIKEIVS
                     NI"
     gene            complement(16440..17177)
                     /locus_tag="RHX21_002932"
     CDS             complement(16440..17177)
                     /locus_tag="RHX21_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone"
                     /protein_id="HDV1988085.1"
                     /translation="MPARHLYFIMTNTWNRLALLIFAVLSLLVAGELQAGVVVGGTRF
                     IFPADKESIAILLTNTSQESWLINSKINRPTRWAGGEVSTVPAPLLAAPPLILLKPGT
                     TGTLRLLRTESDILPVDRETLFELSIASVPSGKVENQSVKVAMRSVFKLFWRPEGLPG
                     DPLEAYQQLRWTRNSQGVQLTNPTPYYINLIQVSVNGKALSNAGVVPPKSQRQTSWCQ
                     AIAPCHVAWRAINDYGGLSAKKEQNLP"
     gene            complement(17143..17658)
                     /locus_tag="RHX21_002933"
     CDS             complement(17143..17658)
                     /locus_tag="RHX21_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415463.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDV1988086.1"
                     /translation="MLKRIIWILCLLGLTGSSELFAHDGTVNISGSFRRNTCVLAQDS
                     KQINVQLGDVSLTRFSHGNYGPEKSFIINLQDCGTDVSTVDVTFSGTPDGVQSEMLSI
                     ESGMDAASGLAIAILDDAKILIPLNQASKDYSLHSGKVPLTFYAQLRPVNSDVQSGKV
                     NASATFVLHYD"
     gene            complement(17666..18208)
                     /locus_tag="RHX21_002934"
     CDS             complement(17666..18208)
                     /locus_tag="RHX21_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV1988087.1"
                     /translation="MKKKTIFQCVILFFSILNIHVGMAGPEQVSMHIYGNVVDQGCDV
                     ATKSALQNIHIGDFNISDFQAANTVSTAADLNIDITGCAAGITGADVLFSGEADTLAP
                     TLLKLTDTGGSGGMATGIAVQILDAQSQQEIPLNQVQPLTPLKAGDNTLKYQLRYKST
                     KAGATGGNATAVLYFDLVYQ"
     gene            complement(18220..19290)
                     /locus_tag="RHX21_002935"
     CDS             complement(18220..19290)
                     /locus_tag="RHX21_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV1988088.1"
                     /translation="MQIIFGEKCVLLLRLFFAAVLMLWCAQTAAYSGQCHTTQGNPYI
                     GVNFGVKTLEEEENTAGVVKDKFYQWNESNDYYVSCDCDKDNVRSGRWAFAADSPLVY
                     LGDNWYKINDYLAAKVLLQVKSSSPTAVPFENVGTGADTRWHICDPGGQRLGGQGASG
                     NSGSFSLKILQPFVGSVVIPPMALARLFECYNIPAGDSCTTTGTSVLVYYLSGTINSL
                     GSCSVNAGETIEVDLGDVFAANFRVVGHKPLGARTAELAIPVRCNTGNAGLVNVNLSL
                     TATTDPSYPQAIKTSRPGVGVVVTDSQNNIISPAGGTLPLSIPDDADSIARMNVYPVS
                     TTGVPPETGRFEATATVRINFD"
     gene            complement(19281..21881)
                     /locus_tag="RHX21_002936"
     CDS             complement(19281..21881)
                     /locus_tag="RHX21_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706863.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis usher protein"
                     /protein_id="HDV1988089.1"
                     /translation="MYRTHRQHSLLSSGGVPSFIGGLVVFVSAAFNAQAETWFDPAFF
                     KDDPSMVADLSRFEKGQKITPGVYRVDIVLNQTIVDTRNVNFVEITPEKGIAACLTTE
                     SLDAMGVNTDAFPAFKQLDKQACVPLAEIIPDASVTFNVNKLRLEISVPQIAIKSNAR
                     GYVPPERWDEGINALLLGYSFSGANSIHSSADSDSGDSYFLNLNSGVNLGPWRLRNNS
                     TWSRSSGQTAEWKNLSSYLQRAVIPLKGELTVGDDYTAGDFFDSVSFRGVQLASDDNM
                     LPDSLKGFAPVVRGIAKSNAQITIKQNGYTIYQTYVSPGAFEISDLYSTSSSGDLLVE
                     IKEADGSVNSYSVPFSSVPLLQRQGRIKYAVTLAKYRTNSNEQQESKFAQATLQWGGP
                     WGTTWYGGGQYAEYYRAAMFGLGFNLGDFGAISFDVTQAKSTLADQSEHKGQSYRFLY
                     AKTLNQLGTNFQLMGYRYSTSGFYTLSDTMYKHMDGYEFNDGDDEDTPMWSRYYNLFY
                     TKRGKLQVNISQQLGEYGSFYLSGSQQTYWHTDQQDRLLQFGYNTQIKDLSLGVSWNY
                     SKSRGQPDADQVFALNFSLPLNLLLPRSNDSYTRKKNYAWMTSNTSIDNEGHITQNLG
                     LTETLLDDGNLSYSVQQGYNSEGKTANGSASMDYKGAFADARVGYNYSDNGSQQQLNY
                     ALSGSLVAHSQGITLGQSLGETNVLIAAPGAENTRVANSTGLKTDWRGYTVVPYATSY
                     RENRIALDAASLKRNVDLENAVVNVVPTKGALVLAEFNAHAGARVLMKTSKQGIPLRF
                     GAIATLDGIQTNSGIIDDDGSLYMSGLPAQGAITVRWGEAPDQICHISYQLTEQQINS
                     AITRMDAICR"
     gene            complement(21906..22607)
                     /locus_tag="RHX21_002937"
     CDS             complement(21906..22607)
                     /locus_tag="RHX21_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HDV1988090.1"
                     /translation="MKTCITKGIVTVSLTAILLSCSSAWAAGKGGIGLAATRLVYSEG
                     EEQISLGVRNTSPDVPYLIQSWVMTPDNKKSADFIITPPLFVLNPANENLLRIMYIGA
                     PLAKDRETLFFTSVRAVPSTTKREEGNTLKIATQSVIKLFWRPKGLAYPLGEAPAKLR
                     CTSSADMVTVSNPTPYFITLTDLKIGGKVVKNQMISPFDKYQFSLPKGAKNSSVTYRT
                     INDYGAETPQLNCKS"
     gene            complement(22690..23232)
                     /locus_tag="RHX21_002938"
     CDS             complement(22690..23232)
                     /locus_tag="RHX21_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415458.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV1988091.1"
                     /translation="MKKSVLTAFITVVCATSSVMAADDNAITDGKVTFNGKVIAPACT
                     LVAATKDSVVTLPNVSATKLQTNGAVSGVKTDVPIALEGCDVTVTKNATFTFSGTADG
                     VQPTAFANQATTDAATNVALQMYLPDGSTSVTPGTETSNIQLADSAEQTVTFKVDYIA
                     TGKATSGNVNAVTNFHINYY"
BASE COUNT         5799 a         6087 c         5457 g         6016 t
ORIGIN      
        1 gttaactacg aaaataggca acttattctt aaggggcaag attaatttat gttttcccgt
       61 caccaacgac aaaatttgcg aggctctttc cgaaaatagg gttgatcttt gttgtcactg
      121 gatgtactgt atatccatac agtaactcac aggggctgga ttgattatgt acacttcagg
      181 ctatgcacat cgttcttcgt cgttctcatc cgcagcaagt aaaattgcgc gtgtctctac
      241 ggaaaacact acagccgggc ttatcagtga agttgtctat cgcgaagatc agcccatgat
      301 gacgcaactt ctactgttgc cattgttaca gcaactcggt cagcaatcgc gctggcaact
      361 ctggttaaca ccgcaacaaa aactgagtcg ggaatgggtt caggcatctg ggctaccctt
      421 aacgaaagta atgcagatta gccagctctc cccttgccac actgtggagt caatggttcg
      481 cgctttacgc acgggcaatt acagtgtggt gatcggttgg ttggcagatg atttgactga
      541 agaagagcat gctgaacttg ttgatgcggc aaatgaaggt aacgctatgg ggtttattat
      601 gcgtccggta agcgcatcct ctcacgccac gagacaactt tccgggctaa aaattcactc
      661 taatttgtat cattaagtaa atttaggatt aatcctggaa ctttttttgt cgcccagcca
      721 atgctttcag tcgtgactaa ttttccttgc ggaggcttgt ctgaagcggt ttccgcgatt
      781 ttcttctgta aattgtcgct gacaaaaaag attaaacata ccttatacaa gacttttttt
      841 tcatatgcct gacggagttc acacttgtaa gttttcaact acgttgtaga ctttacatcg
      901 ccaggggtgc tcggcataag ccgaagatat cggtagagtt aatattgagc agatcccccg
      961 gtgaaggatt taaccgtgtt atctcgttgg agatattcat ggcgtatttt ggatgataac
     1021 gaggcgcaaa aaatgaaaaa gacagctatc gcgattgcag tggcactggc tggtttcgct
     1081 accgtagcgc aggccgctcc gaaagataac acctggtaca ctggtgctaa actgggctgg
     1141 tcccagtacc atgacactgg ttttattcct aacaatggtc cgacccacga aaaccaactg
     1201 ggtgcaggtg cttttggtgg ttaccaggtt aacccgtatg ttggttttga aatgggttac
     1261 gactggttag gtcgtatgcc gtacaaaggc gacaacatca acggtgcata caaagctcag
     1321 ggcgttcaac tgactgctaa actgggttac ccaatcactg acgatctgga cgtatacact
     1381 cgtctgggtg gtatggtatg gcgtgcagac accaaggcta acgtacctgg tggcgcatcc
     1441 tttaaagacc acgacactgg cgtttctccg gttttcgcag gtggtgttga gtacgcgatc
     1501 actcctgaaa tcgctacccg tctggaatac cagtggacca acaacatcgg tgacgcaaac
     1561 accatcggta ctcgtccgga caacggtctg ctgagcctgg gtgtttccta ccgtttcggt
     1621 cagggcgaag cagctccggt agttgctccg gctccagctc cggcaccgga agtacagacc
     1681 aagcacttca ctctgaagtc tgacgttctg ttcaacttca acaaagcaac cctgaaaccg
     1741 gaaggtcagg ctgctctgga tcagctgtac agccagctga gcaacctgga tccgaaagac
     1801 ggttccgtag ttgttctggg ttacactgac cgcatcggtt ctgacgctta caaccagggt
     1861 ctgtccgagc gccgtgctca gtctgttgtt gattacctga tctccaaagg tatcccggca
     1921 gacaagatct ccgcacgtgg tatgggcgaa tccaacccgg ttactggcaa cacctgtgac
     1981 aacgtgaaac agcgtgctgc actgatcgac tgcctggctc cggatcgtcg cgtagagatc
     2041 gaagttaaag gcatcaaaga cgttgtaact cagccgcagg cttaagttct cgtctggtag
     2101 aaaaaccccg cagctgcggg gtttttttcg cctttagtaa attgaactga cttcgtcagt
     2161 tattccttac ccagcaatgc ctgcagatca tgcttcaaag aagacatttt attcgcgtat
     2221 ttctctttgt tttccgcatc ttcaatcagc tgaacaatcg tttcagaaag cgttttaccg
     2281 cgacgctgcg caagaccagc cagacgttgc cagacaataa attccagatc gatcgatttt
     2341 ttgcgcgtat gctggtgttc cgcattaaaa tggcgcttcc gtctggcccg aatggtttgc
     2401 ttcatgcgat tgaccagttc cggattcata tgcttgtcaa tccagccatt taccagcacg
     2461 ggttcatttt ccagcgagag caacacatcg acggcttcct gggcggcact ggcttctatg
     2521 taacgggtga ttaactcccc ttcgcgatgc ttcttcacca gatacttcca tttccaaccg
     2581 ctttcaagat tttcaagttg ttgatatttc atagcgatct caatgttacc gtgtaactct
     2641 ttacagaata tcagcttttt aggccagtga agaaaagaat ctccatcctg tgagctttaa
     2701 cgcccatgcc aggagtattg tcggtgcttt ctacgtgtgc tgtagtgccg gttacggtat
     2761 aatcgcggct ttgacaacag actaaaaaac atcaactttg accattacga aacttgcatg
     2821 gcgtgacctg gttcctgata ccgatagcta tcaggaaata tttgctcagc cacatttgat
     2881 tgacgaaaac gatcctttat tcagtgatac tcaaccgcga ctgcaattcg cactggagca
     2941 gttgctgcat acgcgagcat cctcctcttt tatgctggcg aaggccccgg aagagtctga
     3001 gtatctgaat cttattgcca atgccgcgcg tacgctacaa agcgatgcag gccaactggt
     3061 gggcggtcac tatgaggttt ccggccactc catccgctta cgtcacgcag tgagtgcaga
     3121 tgataatttt gcgactttaa cgcaagttgt cgctgccgac tgggtagaag cggagcaact
     3181 ctttggctgc ctgcgccagt ttaatggcga cattaccctg cagcctggtc tggtgcatca
     3241 ggcaaatggc ggtattctca tcatctcttt gcgtacactg ctggcgcaac ctctgctgtg
     3301 gatgcggctg aaaaatatcg ttaaccgcga gcgttttgac tgggttgcgt ttgatgagtc
     3361 gcgccctctc cccgtctctg tgccttcgat gccattgaag ctgaaagtca ttctggtagg
     3421 cgaacgcgaa tcattggctg atttccagga gatggagcca gagctttcag agcaggctat
     3481 ttatagcgaa tttgaagata ctctgcagat tgtcgatgca gagtcagtaa cccagtggtg
     3541 tcgctgggtg acatttaccg ccagacataa tcacttacct gcaccgggag cggatgcctg
     3601 gccggtactt atccgcgaag cagcacgcta caccggtgaa caagaaacac ttccgcttag
     3661 cccgcagtgg atcctccgcc agtgtaaaga ggtcgcctcc ctgtgtgatg gcgacacctt
     3721 ctccggcgag cagctaaact taatgctgca gcagcgtgaa tggcgcgaag gtttcctcgc
     3781 tgaacgtatg caggatgaga tccttcagga gcaaatcctg attgaaaccg aaggcgaacg
     3841 catcgggcaa attaacgccc tttcggtcat tgaatttccg ggtcatccac gcgcttttgg
     3901 cgaaccttct cgcattagct gcgttgtgca tattggcgat ggtgaattca ccgacatcga
     3961 acgcaaagcg gagcttggcg gcaatatcca tgcgaaaggg atgatgatca tgcaagcgtt
     4021 cctgatgtcg gaactacagc ttgagcaaca gatccccttc tcagcatcgc tgacatttga
     4081 gcagtcatac agtgaagttg atggagatag tgcctcgatg gctgaactct gcgccctgat
     4141 aagcgccctc gccgatgtgc cggtgaatca gagtatcgct atcacaggtt cagtcgatca
     4201 gttcggtcgc gcccagccgg tcggtggttt aaatgagaaa atcgaaggct tctttgctat
     4261 ttgccagcaa cgtgagttaa ccgggaaaca aggtgtcatt atccccacag ctaacgttcg
     4321 ccatttaagt cttcacagtg aactggtgaa agcggtagaa gaaggcaaat tcaccatctg
     4381 ggcagtagac gatgtgactg acgcactgcc gttattatta aatctggtgt gggatggcga
     4441 aggccaaacg acgctgatgc aaaccatcca ggaacgtatc gcgcaagcat cgcaacagga
     4501 aggacgtcac cgttttccat ggccattacg ttggctgaac tggtttattc cgaactgatc
     4561 ggacttgttc agcgtacacg tgttagctat cctgcgtgct tcaataaaat aaggcttaca
     4621 gagaacatgg tagataaacg cgaatcctat acaaaagaag accttcttgc ctctggtcgc
     4681 ggtgaactgt ttggcgctaa aggcccgcaa ttgccagcac cgaacatgct gatgatggac
     4741 cgtgtggtca aaatgaccga aacgggtggt aacttcgaca aagggtatgt tgaagcagaa
     4801 ctggatatca atccggatct gtggttcttc ggatgccact ttattggcga tccggttatg
     4861 ccgggatgcc tgggcctgga cgcaatgtgg cagctggtag ggttctacct cggctggctg
     4921 ggcggcgaag gtaaaggccg cgcgctgggc gttggcgaag tgaaattcac tggtcaggta
     4981 ctgccgacag cgaaaaaagt gacctaccgt attcacttta aacgcattgt taaccgtcgt
     5041 ctgattatgg gcctggcgga tggcgaagtg ctggttgatg gtcgtcttat ctataccgcc
     5101 agcgacctga aagtcggtct gttccaggat acgtctgcct tctgattata atcagacaga
     5161 gtatcaaaag gcgaaacctc cgcaatgcgg aggtttcttt ttaaagagac agaatcaggc
     5221 cattactacc ctgtccgcca tggcttctcg ccagcctccc agccattgtg acctttgatt
     5281 cagcgtctga tagggacaca tttcttttga gcgtccggcg atgccggcct gataaccacg
     5341 ttgatgtgcc cgttccaggc gatctcgttt ttgtctcttc atgcctcgtt tccctcatac
     5401 tggtttctgg tggaaaagaa aacagtgatt actaaatgtg caatcacagt taagcaatac
     5461 cgcgaatcat aactgccgtc aatgcgcaaa attcacgcca ctgtcatatt tgtgagctac
     5521 acgggcatgt cggttgtaca aaaaatgtga agaggaacaa atttttccgc acgttagaaa
     5581 caaaaaaacc gcctcaggca acataccgga gacggttata tttacaaatc tttataatta
     5641 aggtagacgc tttatctctt gtgcaataga agcggcttcc tgactccaga caccggccag
     5701 cactttaacc atctcatcgt aaccatcctg agtttgcact ccttccagac ggaacggacg
     5761 tttgatcagt tgtccctggt ggttcaacag ccactcacca ctgacaatga ccttgccatc
     5821 atagcgaccg ttaaactccg ttacggtaac attgagcgtg tcctgggcgc ttcccagagg
     5881 ctgggaggca accacccagc cgggcagttg cgtactcagg ttggcaacca gggtgttgcg
     5941 caactgttga tccaacgggc tggcccacaa gttgttgttg gcaatcacat acttcacatc
     6001 actggtttga taaaccacac cattccccgc cagatagtca ggaacagtga cctgctctac
     6061 ccataacaga cgattgccct ggctggcggt actttgtgta ccgctctgca ccacaggtaa
     6121 ctggtaatag tttttattaa tttcgccgga gctgcatccg accagccaca gtgctgcaat
     6181 cgtcactagc cactttttca ttgtttcgcc ctcttcggct ctggatcttt tttgtccttc
     6241 gcttcaaata ccagcgcgtt actcttctca ttgagcgttt tcagcaccgg ttgcagttct
     6301 cgcaacacct gatcaaggcg ctgcatatcc gccaccatct tgttgtaggc tgcggagcca
     6361 ggctggaagc cctgcatgct gcgattcaat tcacgcaacg ttgactgcat atccgtcggc
     6421 aactgctgca tcgactggct agcgaggatc ttgttcatgc tatccagcgt cgtttgcagg
     6481 tttttcattg tgcgctgact ttcagaaagc gtactggttg cctgttcaat catcggattc
     6541 aatggcagtt tgttgatctt atccaacgct tccatcagtc gttgctggat ttgcgccagg
     6601 ccgccgctaa cggtcgggat aatctgataa ccattaaatt cacgaatacc ggttattgca
     6661 ggcgtatttg gatagaaatc gagatcaaca tacagtgcac cagtgaccag gtttccggtt
     6721 ttcagcgatc cgcgtaaacc acgtttcaac aattcgccaa ggtgctcaac aacatccgca
     6781 ttttcgccaa gctgcatttt cagccgctct ggctcgatac gaatcagtac cggaatacgg
     6841 taatcatcgt taaatgtctg acgcatattc ggcgcaaaga atggcacttt gcttacggta
     6901 cccaggcgaa taccccggaa ctctaccgga gctcccggtt gcagaccgcg taccgaatct
     6961 ttaaagaaca tcagataatc aatgtgatcg gtgtacaacg aatcctgaat gctcttctga
     7021 tcatcataca aaacgaaagc tgttttaggt gccactggct gccctaaatc cagaccttcc
     7081 ggcacatcaa agctgacacc gccactcagc agcgttgtca atgagcccat ctccacacgc
     7141 atccctgctg acgtcagatc aaccgcaatg ccactatctt tccagaagcg aacattgttg
     7201 gtcaccagtc ggtcataagg tgcattgatg aacagttgat agctgatatt gcgtttttgt
     7261 gtatcgaagg tgctggtttc aaccgaacct acccgatagc cacggaacag caccggatct
     7321 cctggcgaga gctgcccggc ttttttgcta tcgagaatca cacggatacc tttcgcatca
     7381 ggcggggcca acggtggcga gtccagcaaa tcgtatttat ccattttgct gcctttcgcg
     7441 cctggctgca gttcgatata aactccagac agcagcgttc ccaggccgct aatcccttcg
     7501 cgaccaatct gcggtttcac cacccaaaag acggtgtctt tatgcagcaa tttttccata
     7561 ccggaattca gccgcgcttt gatttcaacg tgcgtcaaat catcagccag tgtggcgctt
     7621 tcaaccacgc cgacgtcaac gctacggctt ttaatggtgg ttttgccacc ttcaattcct
     7681 tccgcattcg cggtgatcag ggtcacttcc ggtccctgat ggctgtaatg ataaaaaaga
     7741 acccaggccc caatgagcgc cgtgacgata ggaaatatcc acacgggaga ccagttcttc
     7801 actttctgga ttttggcttc cccattatta gattccatac tgtcaggact cctcatgctc
     7861 tgattcaggt tgacgatccc acgacaaacg cgggtcaaac gtcatagcag aaaacattgt
     7921 cattatgacg actaaagcaa acattaatgc acccattgcc ggataaatac tcattaaacc
     7981 tcccatacgc accagcgccg agagcaccgc gataacgaaa acgtcaatca tcgaccagcg
     8041 gcctacaaac tcaacaactt cataaatcaa atgcattctt tcactgtcgc gcttgccatg
     8101 ccctttggca tcccaacaca gccacgcgat ggcgatcatc tttaacgttg gcaccataat
     8161 actggccaga aagatcaccg cagcgacggg ataagagcct tcgctccata acagaatgac
     8221 cccagcgaga atcgtcgacg gcatcttcga gcctaataaa tccgtcacca tgatgggcaa
     8281 aatattagcc ggaagataca gcatgatgga cgttacaagc agcgcgagtg tccactgcag
     8341 gctgtttcta cgccgaacgt accctttggt actacaacgc gggcacacgg gttcatcagc
     8401 aggaaggatt gccgtacaac aggagcacga acgcagcccc tgacgtatcc ccgtgacgcc
     8461 tggttttagc ggctggcgca gttctggcat cggggcgatg tcgtcccata accagcgacg
     8521 atcaacgcac tgaaaagcgc gcagttgcag gacacaaaat aaacaccagg ggagaaagct
     8581 gctgcctacc ccaatgctgc cgtaagccat cagtttaacg aaactgacca gcacaccagc
     8641 gaggaaaatc tccgccattc cccaggtttt gagttgaaaa agcacccgtg ccagttgctc
     8701 ttttaaacgg accggtaatt ccgcgcgatt caccagtaac agaatggtta tcagacaaaa
     8761 cgcgggaacc agttgcacaa acaacaggaa aaaggtgccg aggctggcgt agtcctcaga
     8821 aaaaagcacg ccgggaattt ccagtaatgt aatttcactg gtaactcctg caacgttcat
     8881 attcacaaaa ggaaacaagt tggacagcaa cagcatgaac agtgcagcca acgcataggc
     8941 ggtaggacgc tgccgagggg catcccacgc cacggttaac gttgtgccac accggggaca
     9001 tgccgctttc tgaccatgct caaggcgcgg taacgccacc agcatgtcac actgcgagca
     9061 caggatgtgc ttcgcggcat gatgatgttc gcacattggt actccttaat gatgcgctat
     9121 tttacagatg actaacaaag tgttggtttt catgcctgat aaacccagtt catcaggcaa
     9181 ttttaccgtt gtcagctgtc tctgtttaaa tcgactattt tgcgatcagc caccattttt
     9241 taacgcttca agatactccc agcgttcaaa ggcttgctcc agctcctgct ctgcagcagc
     9301 catatcggcg agcacttttt gtgtctgctc atgcggctga ctgaagaagg aagcatccgc
     9361 cacttgcgtc tgtaaagctt ccagcttcgc ctccagatct tcaagcaatt gcggtagctg
     9421 ctccagttcg cgctgcaatt tatagcttag tttgctactg ctgcgtttta cagtttctgc
     9481 ttttggcacg gcggcttctt cgcttttttt caccgcaggc tgtttgagcg ccacatactg
     9541 ttcttgctga ccacgggcat catgataacc gccaacataa cgaccaattt taccgccgcc
     9601 ttcgaagatc cagcattctg taacggtgtt atcgacaaac tgacgatcgt ggctaaccag
     9661 caataccgtg ccctgatagc tgtcgatcag ttcttccagc agttccagcg tttcgacatc
     9721 aagatcgttg gtcggttcgt caagaatcaa taagttgctt ggtttgagga acaaacgcgc
     9781 cagtagcaag cggttccgct caccgccaga aagcgcacgt accggcgtca tcgcccgttt
     9841 cggatggaac agaaagtcct gcaaatagcc caatacgtgg cgtggcttgc cattaaccat
     9901 cacctcttgc ttaccttcgg caaggttatc catcaccgtt ttatcgggat ccagttccgc
     9961 gcggtgctga tcgaaataag ccacttccag tttggtgcca acgtgaatac gcccgctgtc
    10021 cgcttgaagc tgaccgagca tcagtttcag cagcgtggtt ttgccgcacc cattcggacc
    10081 aatcagggca attttgtcgc cacgtagaac ctgggccgaa aaatctttca ccagttgctt
    10141 accgtcaacc tggtagcaaa cgtcttccat ttcgaaaacg atcttaccgg agcggctggc
    10201 ctcttccacc tgcatctttg cggtacccat cacttcgcga cgttcaccac gctcgcgacg
    10261 cattgctttc agggcgcgta cgcggccttc attacgggta cggcgtgctt tgatcccctg
    10321 gcggatccac acctcttcct gcgccagttt gcgatcgaac tcggcatttt gtagttcttc
    10381 cacgcgcagg gcttcttctt tttcctgcag gtactggtcg taattccccg gataggtcac
    10441 cagcttgccg cgatcgagat caacaatgcg cgtcgccata ttgcggataa acgaacggtc
    10501 gtgggagatg aaaataatcg tcccattgaa ggttttaagg aacccttcca gccagtcgat
    10561 ggtttcgata tccaggtggt tagtcggttc gtcgagcagc aaaacgcgcg gattgctcac
    10621 cagcgcgcgt cctaatgccg ctttacgcaa ccagccgccg gaaagcgacg acagcgcaac
    10681 attaggatct aaccccagtt gcgccagcac ttcgttgatg cggttttcca gctgccacag
    10741 gttgtggtga tccagctgtt cctgaacctt cgccagttcg ttgagatttt tctcgctcgg
    10801 gtcgttcatc accaggcgcg aaatatcgtg atagcgtttc aggtattccg cttgttcttc
    10861 aatgccttcg gcaacgaaat cataaacgct gccctcaacg ttacgcggcg gatcctgttg
    10921 cagacgagcc acgatcaaat cttgctcgta aataatgcgc ccgtcatcca gcccctgttc
    10981 acggttgagg atcttcatta acgtcgattt gcccgcgccg ttacggccta ccagacaaac
    11041 acgttcgtta tcttcgatat gcagttctgc gttatcgaga agcggcgcgt cgctgaacga
    11101 cagccatgca ccatgcatac tgattaatga cattactatt cctttcaggc tgcggtaatc
    11161 agccagcagt tgtggatctg gcggttacgg gcgaaatcct gggagagcgt tttttgcgta
    11221 atttcttgtg ctttcagtcc cagttttgcc agcccgtcga gatccatacg gaagccacgt
    11281 ttgttgttcg agaacatgat cgtcccacct gcacgcagca gacgtttcaa atctttcatc
    11341 agcgccagat gatcgcgctg aacatcaaac gcatcttcca ttcgttttga gttagagaag
    11401 gttggcggat cgataaagat cagatcgaac tgttcatttg cctcacgcag ccacgccagg
    11461 caatcggcct gaatcaggcg atgcgcacgc ccggttaggc cattcagacg caggttgcgt
    11521 tctgcccact ccagataagt acgcgacata tccacggtgg tggtgctgcg tgcaccgcct
    11581 aatcccgcat gcacggtggc gctgccggta taagagaaca ggttgaggaa atctttgcct
    11641 ttgctcatct ggccgagcat acgacgggcg atacggtgat cgaggaacag accggtatcg
    11701 aggtaatccg tcagattcac ccacaagtga gcgttatatt cggtaacttc cagaaactcg
    11761 cccttctcgc ccagtttctg gtactgattt ttgcccttct gacgttcacg ggttttcagc
    11821 accagtttgt ttggcgcaat ccccagtacc gaaatggttg cagcgataat atcgaacaga
    11881 cgctgacgcg ctttgtgagc atcaatagtt tttggcggtg catactcctg caccaccacc
    11941 cagtcggcat aacggtcaac ggcaacgtta tattccggca gatcggcgtc atacaggcgg
    12001 taacattcaa ttccttcctg acgagcccac ttctcgaatt ttttgaggtt cttacgcagg
    12061 cggttggcgt agtcttccgc taccatcgcc ggtttgctgt ctggagtgct ttcggcaacg
    12121 tggtaatttt tctgtacgca gtccagcggg ccgtttttcg ccttgtactg tttgtctgca
    12181 cgcagctgca agcagcttag cagatccggc gaggcactaa acaaagagag attccagcca
    12241 ccaaactggt ttttcatgat ccgacccagc aggctatgca gcgcaatcag cgccggttcg
    12301 ctgtccagac gttccccgta tggcgggttg ctcaacactg tgccgtacgg ccctttcggc
    12361 agcggattgg tcagttgcgc gacatctttc acctcaaagg tgatcagttc accaatcccc
    12421 gcaagacggg cgttagtgcg cgcacgttga atcacccgtg cgtcgctgtc cgaaccgtaa
    12481 aaatgagagc tatactcagc caggccttta cgggcacgag tttgcgcttc cgctttcact
    12541 tcctgccaga tagcttcatc atgctgcgcc cagccgctaa agccccaacg cccacggtgc
    12601 aagcctggtg cgcgatcggt cgccagcatc gccgcttcaa tcagcaacgt accggaacca
    12661 cacatcggat cgagcagcgg tgttcctggc tgccagccgg atcgcatcac aatagcggct
    12721 gccagggttt ctttgatcgg cgcaatacca gcacgatcgc gatagccacg cagatgtaaa
    12781 ccatcaccac tcagatcaag agcgatactg gcggtttctt tatgcagcca gacgttaacg
    12841 cggatatccg gcgcatcgcg atcaacattt ggacgcggca gatttttccg cgtgaaagca
    12901 tcgacgatcg cgtctttcac tttcatcgcg ccgtactgac tgttgcggat ggtgtcattc
    12961 aaaccactga agtggacagc gaaggtcgcg ccaggattaa acatctctgt ccagttgatc
    13021 gcctgaacac cgagatagag gtctaaatcg ctgtaaacct tacactcgcc cagcggcaac
    13081 ataatacgcg aggccaggcg gctccacatc aggctctggt aaacaagccg tgtgtcgccc
    13141 ttgaaatgga ccccaccctg aaccacctgg cattcaacgg cccccaggtt ttccagttca
    13201 gtttttaaca gctcttccag cccacgggcc gtactggcaa acagagaatt catatcgtca
    13261 cttttactct aagagcctac cgcagtaggc gtaattgttg cagtcagtct gaacatggac
    13321 agcgcggaga aaccggagcg tacacaagta cgtgaggatt tcgagcacaa cccagggcca
    13381 aactgacaaa taaaatagcc taatgggaca ggcgctaaga aaattgttgc gcattatagc
    13441 taataagcgc gtcatgtcat aaagttgagg gcttattttc atttgaggac cgcaccgtgg
    13501 cgacattaac ccggcttttt attcatcctg ttaaatcgat gcgcggcatt ggtcttacac
    13561 atgctctggc agatgacagt ggtctggcct tcgatcgcat ctttatgatt acggaacctg
    13621 atggtacgtt tattaccgct cgccagtttc cccagatggt acggtttact ccttcacctg
    13681 tgcatgatgg cttgcatctc accgcaccag atggcagtag cgcatatgtc cgttttgctg
    13741 atttcgccac acaagacgca ccaaccgaag tttggggcac acattttacc gcgcgaattg
    13801 cgccagacgc gatcaacaaa tggttaagtg gatttttctc ccgcgaagtg caattacgct
    13861 gggtggggcc acaaatgacc cggcgcgtga aacgccacaa cactgtcccc ctgtcatttg
    13921 ctgatggcta tccttacctt cttgctaacg aagcctcgtt acgtgatctc caacaacgtt
    13981 gtccggccag tgtaaaaatg gagcaattcc gccccaatct ggtggtttcc ggcgcgtcag
    14041 cctgggaaga agatcgctgg aaagtgattc gcattggtga tgtggtgttt gatgtggtta
    14101 aaccttgtag ccgctgtatt ttcaccaccg tcagcccaga aaaagggcaa aaacatccgg
    14161 caggcgaacc attaaaaaca ttgcaatctt tccgcactgc ccaggataac ggcgatgtcg
    14221 attttggtca gaatttaatt gcccgtaata gcggcgtgat tcgcgttggc gatgaggtgg
    14281 aaattctggc aacggctccg gcaaaaattt acggcgcagc tgccgctgat gataccgcca
    14341 acatcacgca acaaccggac gccaatgtag atattgactg gcagggacag gcatttcgtg
    14401 gaaataacca acaagtgttg ctggagcaat tagaaaatca gggaattcgt atcccttatt
    14461 cttgccgcgc gggcatttgt ggaagttgcc gtgttcagct tttagaaggc gaagtcacgc
    14521 cgctgaaaaa atcagcaatg ggcgatgatg gcaccattct ttgctgtagc tgtgtaccga
    14581 agactgccct taagctgacg cgttagactg cctgttcaag gctgaagctg tcaacattaa
    14641 cctgcggttt cagcctgtcg ttcatgattt taatggcgtc gcccaactgc atcgcgcgac
    14701 ccgcaataac aacgcagggt tgcgccagca gacatagcgc ggcattctcg ccagattcaa
    14761 cgaccagtaa attcacttgc tcgttagtgt cgctcaacca aacgcaggcc gcatcgccct
    14821 gcatgggcac ccacatttca ccatgggaga caaaatgcca gcttttcggc atttgcggtt
    14881 tgagataacg aattgctacc agtgcattca gcaccagttc ggctttttgt tctttggata
    14941 acggcagatc acggcatttt tcttcaaaag aaaaatagag tgctgcatca tcaacacaaa
    15001 aaccggaggg attaaaggca tctggtgtga gcattttacg agcaaaacgc gagcgaaata
    15061 acataccatt ggctaaatcg agcatcattc gatcgtgctc ttcatcataa taccagcgcc
    15121 agttatcgtc aggtttaatt cgcatgcgga ttctcccacc taaatcattc tgcgcaacat
    15181 tgtcctttgc cgcttcgttt attgccctaa ataagaaaag actaaaatgt ataaataagc
    15241 aacaggtaag gaatataaaa caaccagggc tggaaataaa gccccggttg tctcataacg
    15301 ttaaaaagga gaaattaatc agatattgct aacgatttct ttaatcaaag gcggtccttt
    15361 gaaaataaat cccgaataaa tttgcaccag cgttgcaccc gcagcaatct tttcacgcgc
    15421 agcgataacc gaatcgatgc ctccaacacc gatgatcggt aagcgaccgt ttaattcctg
    15481 tgacaagcgg cgaataattt ctgtgctttt taactgaagc ggacgaccac ttaagccacc
    15541 ggtttgatcg caatttttca ttccctgaac cagagaacga tcgagtgtgg tattggttgc
    15601 aataacgcca tcaatattat ggcgaactaa gctgtcagca acctggatca attcttcttc
    15661 agaaagatcc ggcgcgatct tcactgcgat cggcacatat ttttgatgga ttttttgcag
    15721 atcgttttgt ttatttttga tcgcgattaa taagtcatcc agcgcttcac catattgcag
    15781 agtgcgtaat cccggtgtat tcggcgagga aatattgatg gcgatataac cagcataagg
    15841 ataaatttta tccatacaaa tcaggtagtc atctttgccc tgctccaccg gcgtatcttt
    15901 atttttgccg atgttaatac ccaggacgcc gtcataatgg gcttttttta cattctcaat
    15961 aagattatcc accccgagat tgttaaagcc cattcgattg atcagacctt cggcatcaac
    16021 caggcggaaa agacgcggct tgtcatttcc aggttgtgga cgcggcgtta cagtgccgat
    16081 ctcaatcgag ccaaacccca ttgcaccaag ggcatcgatg cactccccgt ctttatcaag
    16141 accggctgcc agaccaagcg gatttttaaa cgtcaggccc atgcagttaa caggtttcgc
    16201 aggcactttc tgccgcacca gtgcttcaaa cggcgttcct gtaatacggc gtaattgctg
    16261 aaaagtaaac tcatgagcgc gctctggatc gagctggaaa agggctttac gaacgaaggg
    16321 gtagtacatg aactctcctg gattcccggt gtgcaaaccg ggggcgtatt atgtgcgagt
    16381 tcggaccaaa agggaattga cctgcggcaa aaaaaacgca aacgttttcc gaacctgttt
    16441 cagggcagat tttgctcctt ctttgcactc aacccgccgt aatcatttat cgcccgccag
    16501 gcgacatgac acggtgcgat tgcctgacac cagcttgtct gacgctggct tttaggtggc
    16561 acaactcccg cattacttaa cgctttacca tttacgctca cctgaatcag gttaatgtag
    16621 taaggcgttg ggttagtgag ttgcacaccc tgcgaattcc gtgtccagcg taattgttga
    16681 taagcttcca gcgggtcgcc cggcaaacct tcgggtcgcc agaacagttt aaataccgag
    16741 cgcatcgcca cttttacgct ctgattttca actttgccgg atggcacgct ggcaatgctt
    16801 aactcaaata gcgtttcgcg atccactggc aagatgtcgc tttccgttct cagcaagcgc
    16861 aacgtgcccg tagtaccggg cttcaggaga ataagcggtg gagcggccag taatggtgct
    16921 ggcactgtcg acacttcccc cccggcccaa cgcgttgggc gattgatttt actgttaata
    16981 agccaggatt cctgactggt attagtcagt aaaatagcta tcgattcttt gtctgccgga
    17041 aagataaatc gcgttccgcc gaccaccact cctgcctgca attcacccgc caccagcagc
    17101 gataaaacgg caaaaatcaa gagcgccaat ctgttccacg tattagtcat aatgaagtac
    17161 aaatgtcgcg ctggcattca ctttacccga ctgcacatca ctattgacag gtcgtaattg
    17221 cgcataaaaa gttaatggca ccttaccgct gtgtaggctg tagtctttac tcgcctggtt
    17281 aagcggaatc aatatcttcg catcatccag aatcgcaatt gccagcccgc tggctgcatc
    17341 cataccactt tcaatggaca gcatttcgct ctgcactccg tcgggggttc ctgaaaaggt
    17401 gacgtcaacc gtgctgacat ctgttccgca atcctgcaaa ttaatgatga aagatttctc
    17461 cgggccataa ttcccgtgag aaaaacgtgt cagcgagaca tcgcctaact gcacattgat
    17521 ttgcttgcta tcctgtgcca gcacgcatgt attacgacga aacgatccgc taatgttgac
    17581 cgtgccatca tgagcaaata actcactact ccccgttaat cccagtaagc acagaatcca
    17641 gattatccgt ttcaacatca ctccttcact ggtaaaccag atcaaaatag agaaccgccg
    17701 tcgcattacc gcccgttgct cccgcctttg tggacttata acgaagttga tatttgagtg
    17761 tgttatcccc ggcttttaag ggcgtaagag gctggacctg attgagcggg atttcttgct
    17821 gactttgcgc atcaagaatt tgcacggcaa tccccgttgc cataccaccg cttccgcctg
    17881 tgtcagttag tttgagcagt gtcggcgcaa gggtgtcagc ctcgccgcta aaaaggacgt
    17941 ccgcgccagt aataccagcg gcacaaccgg tgatatcgat attcaaatca gcagcagtgc
    18001 ttacggtatt cgcggcctga aaatcactga tattaaaatc accaatatga atattttgta
    18061 atgcactttt ggtggcgaca tcacagccct gatcgaccac attcccataa atatgcatac
    18121 taacttgttc aggcccagcc atcccgacat ggatgttaag aatgctaaag aacaagataa
    18181 cgcactgaaa tatcgttttt ttcttcatac gttcacgcgt taatcaaaat ttattctcac
    18241 cgttgccgtg gcttcaaatc gcccggtttc tggtggtaca cctgtcgtgc tgactggata
    18301 gacattcatt cgcgcgatac tgtctgcatc atcaggaata gagagcggta atgttccacc
    18361 agcaggggaa ataatgttgt tctggctatc ggtcaccacc acgcccacgc caggacgtga
    18421 cgtcttaatc gcctggggat agctggggtc tgtggttgcc gtcagactca ggttgacgtt
    18481 aactaacccc gcgtttcccg tgttacacct gactggaatt gcgagttctg ccgttctggc
    18541 cccaaggggt ttatgcccta caacacgaaa gttagccgca aatacgtcgc ccagatcgac
    18601 ctcgatagtc tctccggcat tgacggaaca tgagccaagt gaattgatcg taccagacag
    18661 gtaatacact aaaaccgatg tacctgtagt cgtgcaggaa tcacctgcgg gtatgttgta
    18721 gcattcaaat aatcgcgcca gcgccatagg aggaatgacg accgaaccaa cgaacggctg
    18781 caatattttc agggaaaagc taccgctatt accgctagcc ccctggccac ctaaacgttg
    18841 accgccggga tcgcaaatat gccatcgtgt atctgcccct gtgcccacgt tttcgaaagg
    18901 aaccgcagta ggagaactgc ttttaacctg caataaaact ttggcggcaa gatagtcatt
    18961 aattttgtac cagttgtcgc ctaaatagac taacggtgaa tccgcggcga atgcccatcg
    19021 gccacttctg acattgtctt tatcgcaatc acaggaaaca taataatcat tcgattcgtt
    19081 ccactgataa aatttgtctt taactactcc agccgtattt tcttcttcct ccagggtttt
    19141 aacgccaaaa ttgacgccaa tatacggatt cccctgagtg gtatgacact gcccgctata
    19201 agcagcagtt tgagcgcacc atagcattaa gacggcggca aaaaatagtc gtagtaataa
    19261 cacgcatttt tctccaaaga ttatctgcat atggcatcca ttcgcgtaat cgcagagtta
    19321 atttgttgtt cggtaagctg gtaactgata tgacaaattt gatcgggagc ttcgccccag
    19381 cgtacagtta tcgctccctg agcgggcaaa ccggacatat agagcgagcc atcatcatca
    19441 ataatgccgc tattagtctg tatgccgtcc agcgtcgcta tcgcgccaaa acgcagcggt
    19501 ataccctgct ttgatgtttt cattaatacc cttgctcccg catgggcatt gaactccgcc
    19561 agaaccaacg cccctttggt gggaaccacg ttgactactg cattttcaag atccacgtta
    19621 cgttttaacg atgccgcatc aagtgcgatt cgattttccc gataagaagt ggcatagggg
    19681 acaacggtat atccgcgcca gtcagttttc agcccggtgc tgttcgccac acgagtattc
    19741 tctgcgcctg gtgctgcaat caggacgtta gtttccccca gcgattgccc cagggtaatg
    19801 ccctgtgaat gggcaactaa actgcctgaa agagcgtagt tcagttgttg ttgactgccg
    19861 ttatcgctgt agttgtagcc cactcgggca tctgcaaacg cccctttgta gtccatgctg
    19921 gcgctaccat tagccgtttt cccctcgctg ttatatccct gttgcacgct gtagctcagg
    19981 ttaccgtcat cgagtagtgt ctccgttaaa cccaggtttt gtgtaatgtg cccttcgtta
    20041 tcgatactgg tgttagaggt catccatgcg taattttttt tcctggtata gctatcatta
    20101 cttctgggga gcaacagatt gagcggcagg gaaaaattta gtgcaaacac ctgatcagca
    20161 tcaggttgac cacgggactt actgtagttc caggaaaccc ccagcgagag atctttaatt
    20221 tgcgtgttgt agccaaactg taatagccga tcctgttgat cggtatgcca gtaagtttgc
    20281 tggctaccac ttaaataaaa cgaaccgtac tcgcctaatt gctgggagat attgacctgc
    20341 agtttgccac gtttggtgta aaacaaattg taataacgcg accacatcgg cgtatcttca
    20401 tcatcaccgt cattaaattc gtagccatcc atatgtttat acatggtgtc ggaaagggtg
    20461 tagaaacccg acgtcgaata gcgatagccc atcaattgaa aattagtgcc caattggttg
    20521 agcgttttgg catacagaaa acgatatgac tgacctttat gttcgctttg gtctgccagc
    20581 gtactcttcg cctgggtcac atcgaacgaa attgctccga aatcgccaag gttaaatccc
    20641 agaccaaaca tggcggcacg gtaatattca gcatattgtc caccaccata ccatgtcgtt
    20701 ccccacggtc cgccccactg caacgtggcc tgggcaaatt tgctctcctg ctgttcatta
    20761 ctattggttc tgtatttcgc cagtgtcacc gcgtatttga ttcgcccctg acgctggagt
    20821 aatggcacgc tggaaaacgg tacgctgtag ctattgacgc tgccgtccgc ttctttgatt
    20881 tcaactaaca aatcaccgct cgacgacgtg gaatagagat cactaatttc aaaagcacca
    20941 ggcgatacat aagtttggta aatggtgtaa ccattttgct taatcgttat ctgggcattg
    21001 cttttggcga taccacgcac cacaggcgca aaccctttca ggctgtctgg cagcatgttg
    21061 tcatctgacg ccagctgcac accacgaaag ctgacactat cgaaaaaatc gcctgcagta
    21121 taatcatcac ctacggtcag ttcgcctttt agtggaataa ccgcccgctg caaatagctg
    21181 ctgagattct tccattctgc ggtttggcca ctactgcgac tccatgttga attgttgcgc
    21241 aatctccatg ggcctaaatt aacgccactg tttaaattca gaaaatagct gtcgccagaa
    21301 tcactgtctg cgctgctatg aatactgtta gccccgctaa acgaatatcc cagtaatagc
    21361 gcgttgatcc cttcatccca acgttcaggg gggacataac cacgggcatt acttttgatg
    21421 gcgatttgcg gtactgaaat ttccagacgg agtttattca cattaaacgt tacgctggca
    21481 tccggaataa tctccgccaa tggcacacac gcttgtttgt ccagttgttt aaaagccgga
    21541 aacgcatcag tattaacacc cattgcatcc aggctttcag tcgtcaaaca ggcggcaatc
    21601 cccttctctg gcgttatctc aacaaaattg acgttgcgcg tatctacaat tgtctgattc
    21661 agaacaatat cgacacgata aacccctggc gttatttttt gtcctttttc gaaacgagac
    21721 aaatcggcca ccattgaggg atcatctttg aaaaaagcag gatcgaacca ggtttcagct
    21781 tgtgcattga acgctgccga cacaaacacc accagcccac caataaacga tggcactcca
    21841 ccagagctta acaggctgtg ttgtcgatga gttctataca tctcgctctc ttaactgaag
    21901 acggcttacg atttacagtt gagttgcggc gtttccgccc cgtagtcatt gatggttcga
    21961 tacgttacgc tgctattttt ggcccccttt ggcagagaaa attggtattt atcaaagggg
    22021 gaaatcattt gatttttaac tacttttcca cctattttca ggtctgtcag ggtaatgaaa
    22081 taaggtgttg ggttactgac cgtaaccatg tcagctgacg aagtgcaacg cagtttcgcc
    22141 ggagcctcgc ctaagggata cgctaaacct tttggtcgcc agaaaagttt gatgacgctt
    22201 tgtgtggcaa tcttcagggt atttccctct tcccgcttcg ttgttgaagg gactgcccgt
    22261 acgctagtga agaaaagggt ttctctgtct ttcgccaacg gcgcaccaat gtacataatg
    22321 cgtaacagat tctcattagc cggattcagc acaaatagcg gtggtgtaat aataaaatct
    22381 gctgattttt tattatctgg ggtcatcacc catgactgaa taagataagg aacatccgga
    22441 ctggtgttac gtacacccag tgaaatttgc tcttcacctt ctgaataaac aagacgtgtt
    22501 gctgcaagtc caatcccgcc tttacctgcc gcccatgcgg atgagcagct gagtaatatt
    22561 gccgttaaac ttacggtcac aattcccttt gttatgcaag ttttcataaa tagtcactct
    22621 taaaaaatat gaatatcccc tccagaacac tagaggggta ctaattaata aaacaattaa
    22681 tgagttctat taataatagt taatatggaa atttgttacc gcattcacat taccagaagt
    22741 cgctttcccc gtagcgatat aatcaacttt aaaggtcact gtttgctcag cagaatccgc
    22801 taactgaata ttcgacgttt cggtaccggg agttaccgat gtagaaccat ctggcagata
    22861 catttgtaga gcaacattcg tcgctgcatc ggtggtagcc tggttggcaa atgctgtagg
    22921 ttgcacgccg tcagccgtac cactaaaggt aaacgtcgca tttttagtta cagtaacatc
    22981 acagccttct aaggcaattg gtacatcagt tttaacgcca gagactgctc cattagtttg
    23041 caacttggtg gcgctgacat ttggcaatgt gactactgaa tctttcgtcg cagctaccag
    23101 ggtacaagct ggagcaataa ctttaccatt aaatgttact ttgccatccg tgatagcatt
    23161 atcatcagct gccataacgc tggacgttgc acataccaca gttataaacg ccgtcaatac
    23221 actttttttc atcgtcatca tcctgatctc ttcgtaaata tgataatgcc tttaaatgac
    23281 attagactta ataataacaa taattgaccg ccatttaaat caagcatact aaatccaata
    23341 agtgacaaat ctttaattt
//
LOCUS       DAPGUL010000071        22460 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.072, whole genome shotgun sequence.
ACCESSION   DAPGUL010000071 DAPGUL010000000
VERSION     DAPGUL010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22460
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.072"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..479
                     /locus_tag="RHX21_002939"
     CDS             <1..479
                     /locus_tag="RHX21_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001458895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDV1988092.1"
                     /translation="IRRDYLHKVTTTVSKNHAMIVIEDLKVSNMSKSAAGTVSQPGRN
                     VRAKSGLNRSILDQGWYEMRRQLAYKQLWRGGQVLAVPPAYTSQRCACCGHTAKENRL
                     SQSKFRCQVCGYTANADVNGARNILAAGHAVLACGGMVQSGRPLKQEPTEMIQATA"
     gene            complement(519..1733)
                     /gene="ydcO"
                     /locus_tag="RHX21_002940"
     CDS             complement(519..1733)
                     /gene="ydcO"
                     /locus_tag="RHX21_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001748359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BenE family transporter YdcO"
                     /protein_id="HDV1988093.1"
                     /translation="MLRCLYAITHEVTMRLFSVPPPTLLAGFLAVLIGYASSAAIIWQ
                     AAIVAGATTAQISGWMTALGLAMGVSTLTLTLWYRVPVLTAWSTPGAALLVTGLQGLT
                     LNEAIGVFIVTNALIVLCGITGLFARLMRIIPHSLAAAMLAGILLRFGLQAFASLDGQ
                     FTLCGSMLLVWLATKAVAPRYAVIAAMIIGIVIVIAQGDVVTTDVVFKPVLPTYITPD
                     FSFAHSLSVALPLFLVTMASQNAPGIAAMKAAGYSTPVSPLIVFTGLLALVFSPFGVY
                     SVGIAAITAAICQSPEAHPDKDQRWLAAAGAGIFYLLAGLFGSAITGMMAALPVSWIQ
                     MLAGLALLSTIGGSLYQALHNERERDAAVVAFLVTASGLTLVGIGSAFWGLIAGGVCY
                     VVLNLIADRNRY"
     gene            1786..2322
                     /gene="sutR"
                     /locus_tag="RHX21_002941"
     CDS             1786..2322
                     /gene="sutR"
                     /locus_tag="RHX21_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SutR"
                     /protein_id="HDV1988094.1"
                     /translation="MENLARFLSTTLKQLRQQRGWSLSRLAEATGVSKAMLGQIERNE
                     SSPTVATLWKIATGLNVPFSTFISPPQPATPSVYDPQQHAMVITSLFPYDPQLCFEHF
                     SIQMASGAISESTPHEKGVIEHVVVIDGQLDLCVDGEWQTLNCGEGVRFAADVTHIYR
                     NGGEQTVHFHSLIHYPRS"
     gene            2395..4356
                     /gene="rlhA"
                     /locus_tag="RHX21_002942"
     CDS             2395..4356
                     /gene="rlhA"
                     /locus_tag="RHX21_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA 5-hydroxycytidine C2501 synthase"
                     /protein_id="HDV1988095.1"
                     /translation="MTVSSHRLELLSPARDAAIAREAILHGADAVYIGGPGFGARHNA
                     SNSLKDIAELVPFAHRYGAKIFVTLNTILHDDELEPAQRLITDLYQTGVDALIVQDMG
                     ILELDIPPIELHASTQCDIRTVEKAKFLSDVGFTQIVLARELNLEQIRAIHQATDATI
                     EFFIHGALCVAYSGQCYISHAQTGRSANRGDCSQACRLPYTLKDDQGRVVSYEKHLLS
                     MKDNDQTANLGALIDAGVRSFKIEGRYKDMSYVKNITAHYRQMLDAIIEERGDLARAS
                     SGRTEHFFVPSTEKTFHRGSTDYFVNARKGDIGAFDSPKFIGLPVGEVLKVAKDHLDV
                     AVTEPLANGDGLNVMIKREVVGFRANTVEKTGENQYRVWPNEMPADLHKIRPHHPLNR
                     NLDHNWQQALTKTSSERRVAVDIELGGWQEQLILTLTSEEGVSITHTLDGQFDEANNA
                     EKAMNNLKDGLAKLGQTLYYARDVQINLPGALFVPNSLLNQFRREAADMLDAARLASY
                     QRGSRKPVADPAPVYPQTHLSFLANVYNQKAREFYHRYGVQLIDAAYEAHEEKGEVPV
                     MITKHCLRFAFNLCPKQAKGNIKSWKATPMQLVNGDEVLTLKFDCRPCEMHVIGKIKN
                     HILKMPLPGSVVASVSPDELLKTLPKRKG"
     gene            complement(4448..4678)
                     /locus_tag="RHX21_002943"
     CDS             complement(4448..4678)
                     /locus_tag="RHX21_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncJ family protein"
                     /protein_id="HDV1988096.1"
                     /translation="MFTKALSVVLLTCALFSGQLMAGHKGHEFVWVKNVDHQLRHEAD
                     SDELRAVAEESAEGLREHFYWQKSRKPEAGQR"
     gene            4900..5076
                     /gene="hicA"
                     /locus_tag="RHX21_002944"
     CDS             4900..5076
                     /gene="hicA"
                     /locus_tag="RHX21_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415954.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin HicA"
                     /protein_id="HDV1988097.1"
                     /translation="MKQSEFRRWLESQGVDVANGSNHLKLRFHGRRSVMPRHPCDEIK
                     EPLRKAILKQLGLS"
     gene            5122..5538
                     /gene="hicB"
                     /locus_tag="RHX21_002945"
     CDS             5122..5538
                     /gene="hicB"
                     /locus_tag="RHX21_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415955.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin HicB"
                     /protein_id="HDV1988098.1"
                     /translation="MRYPVTLTPAPEGGYMVSFVDIPEALTQGETVAEAMEAAKDALL
                     TAFDFYFEDNELIPLPSPLNSHDHFIEVPLSVASKVLLLNAFLQSEITQQELARRIGK
                     PKQEITRLFNLHHATKIDAVQLAAKALGKELSLVMV"
     gene            5617..7023
                     /locus_tag="RHX21_002946"
     CDS             5617..7023
                     /locus_tag="RHX21_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDV1988099.1"
                     /translation="MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVS
                     HAYQLLESQGYIIARPQSGYYVAPQAIKMPKAPVIPVTRDEAVDINTYIFDMLQASRD
                     PSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYAL
                     QGITISPDEIVITAGALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSV
                     ATDVKEGIDLQALELALQEYPVKACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTL
                     IEDDVYSELYFGREKPLPAKAWDRHDGVLHCSSFSKCLVPGFRIGWVAAGKHARKIQR
                     LQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKI
                     HHSDSGYFLWLELPEPLDAGELSLAALTHHISIAPGKMFSTGENWSRFFRFNTAWQWG
                     EREEQAVKQLGKLIQERL"
     gene            7268..8413
                     /locus_tag="RHX21_002947"
     CDS             7268..8413
                     /locus_tag="RHX21_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDV1988100.1"
                     /translation="MSKTFARSSLCALTMTIMTAHAAEPPTNLDKPEGRLDIIAWPGY
                     IERGQTDKQYDWVTQFEKETGCAVNVKTAATSDEMVSLMTKGGYDLVTASGDASLRLI
                     MGKRVQPINTALIPNWKTLDPRVVKGDWFNVGGKVYGTPYQWGPNLLMYNTKTFPTPP
                     DSWQVVFVEQNLPDGKSNKGRVQAYDGPIYIADAALFVKATQPQLGISDPYQLTEEQY
                     QAVLKVLRAQHSLIHRYWHDTTVQMSDFKNEGVVASSAWPYQANALKAEGQPVATVFP
                     KEGVTGWADTTMLHSEAKHPVCAYKWMNWSLTPKVQGDVAAWFGSLPVVPEGCKASPL
                     LGEKGCETNGFNYFDKIAFWKTPIAEGGKFVPYSRWTQDYIAIMGGR"
     gene            8431..9444
                     /locus_tag="RHX21_002948"
     CDS             8431..9444
                     /locus_tag="RHX21_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDV1988101.1"
                     /translation="MTYAVEFDNVSRLYGDVRAVDGVSIAIKDGEFFSMLGPSGSGKT
                     TCLRLIAGFEQLSGGAISIFGKPASNLPPWERDVNTVFQDYALFPHMSILDNVAYGLM
                     VKGVNKKQRHAMAQEALEKVALGFVHQRKPSQLSGGQRQRVAIARALVNEPRVLLLDE
                     PLGALDLKLREQMQLELKKLQQSLGITFIFVTHDQGEALSMSDRVAVFNNGRIEQVDS
                     PRDLYMRPRTPFVAGFVGTSNVFDGLMAEKLCGMTGSFALRPEHIRLNTPGELQANGT
                     IQAVQYQGAATRFELKLNGGEKLLVSQANMTGEELPATLTPGQQVMVSWSRDVMVPLV
                     EER"
     gene            9445..10386
                     /locus_tag="RHX21_002949"
     CDS             9445..10386
                     /locus_tag="RHX21_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV1988102.1"
                     /translation="MAMNVLQSPSRPGLGKVSGFFWRNPGLGLFLLLLGPLMWFGIVY
                     FGSLLTLLWQGFYTFDDFTMSVTPELTLANIRALFNPANYDIILRTLTMAVAVTIASA
                     ILAFPMAWYMARYTSGKMKAFFYIAVMLPMWASYIVKAYAWTLLLAKDGVAQWFLQHL
                     GLEPLLTTFLTLPAVGGNTLSTSGLGRFLVFLYIWLPFMILPVQAALERLPPSLLQAS
                     ADLGARPRQTFRYVVLPLAIPGIAAGSIFTFSLTLGDFIVPQLVGPPGYFIGNMVYSQ
                     QGAIGNMPMAAAFTLVPIVLIALYLAFVKRLGAFDAL"
     gene            10376..11170
                     /locus_tag="RHX21_002950"
     CDS             10376..11170
                     /locus_tag="RHX21_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV1988103.1"
                     /translation="MHSERAPFFLKLAAWGGVVFLHFPILIIAAYAFNTEDAAFSFPP
                     QGLTLRWFSVAARRSDILDAVTLSLKVAALATLIALVLGTLAAAALWRRDFFGKNAIS
                     LLLLLPIALPGIVTGLALLTAFKTINLEPGFFTIVVGHATFCVVVVFNNVIARFRRTS
                     WSLVEASMDLGANGWQTFRYVVLPNLSSALLAGGMLAFALSFDEIIVTTFTAGHERTL
                     PLWLLNQLGRPRDVPVTNVVALLVMLVTTLPILGAWWLTREGDNGQ"
     gene            11192..12616
                     /gene="patD"
                     /locus_tag="RHX21_002951"
     CDS             11192..12616
                     /gene="patD"
                     /locus_tag="RHX21_002951"
                     /EC_number="1.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminobutyraldehyde dehydrogenase"
                     /protein_id="HDV1988104.1"
                     /translation="MQHKLLINGELVSGEGEKQPVYNPATGDVLLEIAEASAEQVDAA
                     VRAADAAFAEWGQTTPKVRAECLLKLADVIEENGQVFAELESRNCGKPLHSAFNDEIP
                     AIVDVFRFFAGAARCLNGLAAGEYLEGHTSMIRRDPLGVVASIAPWNYPLMMAAWKLA
                     PALAAGNCVVLKPSEITPLTALKLAELAKDIFPAGVINVLFGRGKTVGDPLTGHPKVR
                     MVSLTGSIATGEHIISHTASSIKRTHMELGGKAPVIVFDDADIEAVVEGVRTFGYYNA
                     GQDCTAACRIYAQKGIYDTLVEKLGAAVATLKSGAPDDESTELGPLSSLAHLERVSKA
                     VEEAKATGHIKVITGGEKRKGNGYYYAPTLLAGALQDDAIVQKEVFGPVVSVTPFDNE
                     EQVVNWANDSQYGLASSVWTKDVGRAHRVSARLQYGCTWVNTHFMLVSEMPHGGQKLS
                     GYGKDMSLYGLEDYTVVRHVMVKH"
     gene            complement(12713..12808)
                     /gene="yncL"
                     /locus_tag="RHX21_002952"
     CDS             complement(12713..12808)
                     /gene="yncL"
                     /locus_tag="RHX21_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response membrane protein YncL"
                     /protein_id="HDV1988105.1"
                     /translation="MNVSSRTVVLINVFAAVGLFTLISMRFGWFI"
     gene            13003..13176
                     /gene="ortT"
                     /locus_tag="RHX21_002953"
     CDS             13003..13176
                     /gene="ortT"
                     /locus_tag="RHX21_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415962.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orphan toxin OrtT"
                     /protein_id="HDV1988106.1"
                     /translation="MSLYQHMLVFYAVMAAIAFLITWFLSHDKKRIRFLSAFLVGATW
                     PMSFPVALLFSLF"
     gene            13262..13495
                     /locus_tag="RHX21_002954"
     CDS             13262..13495
                     /locus_tag="RHX21_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcY family protein"
                     /protein_id="HDV1988107.1"
                     /translation="MSHLDEVIARVDAAIEESVIAHMNELLIALSDDAELSREDRYTQ
                     QQRLRTAIAHHGRKHKEDMEARHEQLTKGGTIL"
     gene            complement(13496..13945)
                     /locus_tag="RHX21_002955"
     CDS             complement(13496..13945)
                     /locus_tag="RHX21_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDV1988108.1"
                     /translation="MNQSLTLAFLIAAGIGLVVQNTLMVRITQTSSTILIAMLLNSLV
                     GIVLFVSILWFKQGMAGFGELVSSVRWWTLIPGLLGSFFVFASISGYQNVGAATTIAV
                     LVASQLIGGLMLDIFRSHGVPLRALFGPICGAILLVVGAWLVARRSF"
     gene            complement(13942..14460)
                     /gene="mddA"
                     /locus_tag="RHX21_002956"
     CDS             complement(13942..14460)
                     /gene="mddA"
                     /locus_tag="RHX21_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine sulfoximine/L-methionine sulfone
                     acetyltransferase"
                     /protein_id="HDV1988109.1"
                     /translation="MSIRFARKADCAAIAEIYNHAVLYTAAIWNDQTVDADNRIAWFE
                     ARTIAGYPVLVSEEDGVVTGYASFGDWRSFDGFRHTVEHSVYVHPDHQGKGLGRKLLS
                     RLIDEARDCGKHVMVAGIESQNQASLHLHHSLGFVVTAQMPQVGTKFGRWLDLTFMQL
                     QLDERTEPDAIG"
     gene            14641..15678
                     /gene="curA"
                     /locus_tag="RHX21_002957"
     CDS             14641..15678
                     /gene="curA"
                     /locus_tag="RHX21_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415966.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent curcumin/dihydrocurcumin
                     reductase"
                     /protein_id="HDV1988110.1"
                     /translation="MGQQKQRNRRWVLASRPHGAPVPENFRLEEDDVATPGEGQVLLR
                     TVYLSLDPYMRGRMSDEPSYSPPVDIGGVMVGGTVSRVVESNHPDYQPGDWVLGYSGW
                     QDYDISSGDDLVKLGDHPQNPSWSLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATG
                     PVGATVGQIGKLKGCRVVGVAGGAEKCRHAIEVLGFDVCLDHHADDFAEQLVKACPKG
                     IDIYYENVGGKVFDAVLPLLNTSARIPVCGLVSSYNATELPPGPDRLPLLMATVLKKR
                     IRLQGFIIAQDYGHRIHEFQKEMGQWVKEDKIHYHEDITDGLENAPQTFIGLLKGKNF
                     GKVVIRVAGDD"
     gene            15876..16541
                     /gene="mcbR"
                     /locus_tag="RHX21_002958"
     CDS             15876..16541
                     /gene="mcbR"
                     /locus_tag="RHX21_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415967.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid/biofilm transcriptional regulator
                     McbR"
                     /protein_id="HDV1988111.1"
                     /translation="MPGMGKMKHVSLTLQVENDLKHQLSIGALKPGARLITKNLAEQL
                     GMSITPVREALLRLVSVNALSVAPAQAFTVPEVRKRQLDEINRIRYELELMAVALAVE
                     NLTPQDLAELQELLEKLQQAQEKGDMEQIINVNRLFRLAIYHRSNMPILCEMIEQLWV
                     RMGPGLHYLYEAINPAELREHIENYHLLLAALKAKDKEGCRHCLAEIMQQNIAILYQQ
                     YNR"
     gene            complement(16577..18679)
                     /locus_tag="RHX21_002959"
     CDS             complement(16577..18679)
                     /locus_tag="RHX21_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HDV1988112.1"
                     /translation="MKIFSVRQTVLPALLVLSPVVFAADEQTMIVSAAPQVVSELDTP
                     AAVSVVDGEEMRLATPRINLSESLTGVPGLQVQNRQNYAQDLQLSIRGFGSRSTYGIR
                     GIRLYVDGIPATMPDGQGQTSNIDLSSVQNVEVLRGPFSALYGNASGGVMNVTTQTGQ
                     QPPTIEASSYYGSFGSWRYGLKATGATGDGTQPGDVDYTVSTTRFTTHGYRDHSGAQK
                     NLANAKLGVRIDEASKLSLIFNSVDIKADDPGGLTKAEWKANPQQAPRAEQYDTRKTI
                     KQTQAGLRYERSLSAQDDMSVMMYAGERETTQYQSIPMAPQLNPSHAGGVITLQRHYQ
                     GIDSRWTHRGELGVPVTFTTGLNYENMSENRKGYNNFRLNSGMPEYGQKGELRRDERN
                     LMWNIDPYLQTQWQLSEKLSLDAGVRYSSVWFDSNDHYVTPGNGDDSGDASYHKWLPA
                     GSLKYAMTDAWNIYLAAGRGFETPTINELSYRADGQSGMNFGLKPSTNDTIEIGSKTR
                     IGDGLLSLALFQTDTDDEIVVDSSSGGRTTYKNAGKTRRQGAELAWDQRFAGDFRVNA
                     SWTWLDATYRSNVCNEQDCNGNRMPGIARNMGFASIGYVPEDGWYAGTEARYMGDIMA
                     DDENTAKAPSYTLVGLFTGYKYNYHNLTVDLFGRVDNLFDKEYVGSVIVNESNGRYYE
                     PSPGRNYGVGMNIAWRFE"
     gene            18921..19982
                     /locus_tag="RHX21_002960"
     CDS             18921..19982
                     /locus_tag="RHX21_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HDV1988113.1"
                     /translation="MHLRHLFSSRLRGSLLLGSLLVASSFSTQAAEEMLRKAVGKGAY
                     EMAYSQQENALWLATSQSRKLDKGGVVYRLDPVTLEVTQAIHNDLKPFGATINNTTQT
                     LWFGNTVNSAVTAIDAKTGEVKGRLVLDDRKRTEEVRPLQPRELVADDASNTVYISGI
                     GKESVIWVVDGENIKLKTAIQNTGKMSTGLALDSKGKRLYTTNADGELITIDTADNKI
                     LSRKKLLDDGKEHFFINISLDTARQRAFITDSKAAEVLVVDTRNGNILAKVAAPESLA
                     VLFNPARNEAYVTHRQAGKVSVIDAKSYKVVKTFDTPTHPNSLALSADGKTLYVSVKQ
                     KSTKQQEATQPDDVIRIAL"
     gene            complement(20097..21596)
                     /gene="ansP"
                     /locus_tag="RHX21_002961"
     CDS             complement(20097..21596)
                     /gene="ansP"
                     /locus_tag="RHX21_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310084.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-asparagine permease"
                     /protein_id="HDV1988114.1"
                     /translation="MSKHDTDTSDQHAAKRRWLNAHEEGYHKAMGNRQVQMIAIGGAI
                     GTGLFLGAGARLQMAGPALALVYLICGLFSFFILRALGELVLHRPSSGSFVSYAREFL
                     GEKAAYVAGWMYFINWAMTGIVDITAVALYMHYWGAFGGVPQWVFALAALTIVGTMNM
                     IGVKWFAEMEFWFALIKVLAIVTFLVVGTVFLGSGQPLDGNTTGFHLITDNGGFFPHG
                     LLPALVLIQGVVFAFASIEMVGTAAGECKDPQTMVPKAINSVIWRIGLFYVGSVVLLV
                     MLLPWSAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLNSGLYCTGRILRSMA
                     MGGSAPSFMAKMSRQHVPYAGILATLVVYVVGVFLNYLVPSRVFEIVLNFASLGIIAS
                     WAFIIVCQMRLRKAIKQGKAADVSFKLPGAPFTSWLTLLFLLSVLVLMAFDYPNGTYT
                     IAALPIIGILLVIGWFGVRKRVAEIHSTAPVVEEDEEKQEIVFKPETAS"
     gene            21862..>22460
                     /locus_tag="RHX21_002962"
     CDS             21862..>22460
                     /locus_tag="RHX21_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HDV1988115.1"
                     /translation="MIKVYGVPGWGSTISELMLTLADIPYQFVDVSGFDHEGASRELL
                     KTLNPLCQVPTLALENDEIMTETAAIAFMVLDRRPDLAPPVGRAERQQFQRLLVWLVA
                     NVYPTFTFADYPERWASDAPEQLKKNVIEYRKSLYIWLNSQLTAEPYAFGEQLTLVDC
                     YLCTMRTWGPGHEWFQDNAQNISAIADAVCQLPKLQEVL"
BASE COUNT         5697 a         5544 c         5813 g         5406 t
ORIGIN      
        1 atatccgcag ggactacctt cacaaagtca caacgaccgt cagcaaaaac cacgcaatga
       61 tagtcattga ggatttgaag gtcagcaaca tgtcaaagtc agcagcgggt acggtcagcc
      121 agccggggcg caatgtccgg gcaaaatcag gtttaaaccg ttcgatactg gatcagggct
      181 ggtatgaaat gcgccgccag cttgcgtaca agcagctctg gcgtggcggt caggtgcttg
      241 ctgttccgcc agcgtataca agccagcgtt gcgcgtgctg tggtcataca gcgaaagaaa
      301 atcgtctgtc acaaagtaaa ttcagatgcc aggtatgtgg atatacagcg aacgccgatg
      361 taaacggcgc tcgtaacatt ttagcggcgg ggcacgccgt tcttgcctgt ggagggatgg
      421 tgcagtcagg ccgcccgttg aagcaggaac ccaccgaaat gattcaggcg acagcctgaa
      481 cgtagcaggg atccacgtcc ttcagggcgt ggaggatgtc aatatcggtt tctgtcagcg
      541 attaaattca acaccacgta acaaacgcct ccggcaatta atccccagaa cgcagaacca
      601 atcccgacca gcgtcaatcc acttgccgtt accagaaatg ccaccaccgc cgcgtcgcgc
      661 tcacgctcat tatgcagcgc ctgatacaaa ctgccgccaa tggtactcaa cagcgccaga
      721 cctgccagca tctggatcca acttacgggc agggcagcca tcatcccggt aatggcacta
      781 ccaaacagac ctgcgagcaa atagaaaatg cctgcaccgg cagctgccag ccaacgttga
      841 tctttatccg gatgcgcttc cgggctttgg caaatagccg cggtgattgc cgcaataccg
      901 acggaataaa cgccgaaagg ggaaaaaacc agtgccagca atccagtaaa tacaattaat
      961 ggcgaaacag gagttgaata tccggctgct ttcattgctg cgatacccgg tgcgttttgc
     1021 gatgccatcg tcaccagaaa aagggggagt gcaacgctca ggctgtgagc aaacgaaaaa
     1081 tcaggggtaa tataagtggg gagaacgggt ttaaagacaa catcagttgt gacaacgtca
     1141 ccttgcgcga taacgatcac gatcccaata atcatcgcgg caattaccgc atagcgtggc
     1201 gcaacggcct tggttgccag ccataccagc aacatacttc cacacaacgt aaattgaccg
     1261 tccagactgg caaacgcctg taaaccaaag cgtaataaaa tcccggcaag cattgccgcc
     1321 gcaagcgagt gcggaataat gcgcatcaga cgagcaaaga gtcccgttat gccgcagagg
     1381 actattaacg cgttggtgac aataaaaacg ccgatggctt cgttaagtgt tagtccctgc
     1441 aatccggtga ccaacaaagc cgcgccaggc gttgaccatg cggtgagaac aggtacgcga
     1501 taccataatg tcagagtcag cgtactgacg cccattgcca gccccagcgc cgtcatccag
     1561 ccagagattt gtgcagtggt ggctccggcg acaatcgctg cttgccagat tattgccgct
     1621 gaactggcgt agccaattaa taccgccaga aaccccgcca gtagcgtggg tggaggaaca
     1681 gaaaacagac gcatagtcac ctcgtgcgtt atagcgtaca ggcaccgtag catttgtccg
     1741 ttataacgca caagtgataa acttccgttt tgccggagga gtcgcatgga aaatctcgct
     1801 cgctttttat ccaccacact taaacaacta cgccagcagc gcggctggag tctttcgcga
     1861 ctggcagaag cgacgggcgt ttctaaagca atgttagggc agattgagcg taatgagtcc
     1921 agtccgacgg tcgcgacatt atggaaaatt gccaccgggt tgaacgtacc attttcaaca
     1981 tttatttctc cgccgcagcc cgctacgcct tcagtttatg atccacaaca gcacgcgatg
     2041 gtgatcactt cgctgtttcc ttatgatcca caactctgct ttgaacactt ctcgattcag
     2101 atggcatctg gtgcaataag cgaatcgacg ccccatgaga agggggtaat cgaacatgtc
     2161 gtcgtcattg atggacaact tgatctgtgc gttgatgggg aatggcagac ccttaattgt
     2221 ggggaaggcg ttcgatttgc tgcagacgtc acgcatatct atcgtaatgg tggggagcaa
     2281 accgtacatt ttcattccct catccattac ccgcgcagtt aagcgggaaa actatttcgc
     2341 aacgtcgcgc ttgtggctaa aatagccgcc atttttcagc tactggataa gaatgtgacc
     2401 gtatcttctc atcgacttga actgttaagc ccggcacgcg atgccgccat tgcccgcgaa
     2461 gctattttgc acggtgccga tgctgtttat atcggcggcc ctggttttgg tgcccgtcat
     2521 aatgccagta atagcctgaa agatattgcc gagctggtgc cgtttgccca tcgttatggt
     2581 gcaaaaattt tcgtcacact taacaccatt ttgcatgatg atgagctgga acccgcgcaa
     2641 cggctgatta ccgacctcta ccagaccggt gtcgatgcgc tgattgttca ggatatgggg
     2701 attctggaac ttgatattcc gccgattgaa ctgcacgcca gtacgcagtg cgacattcgt
     2761 acagtagaaa aagcgaagtt cctctctgat gttggcttca cgcagattgt gctggcgcga
     2821 gagctgaatc ttgagcagat ccgcgcgatt caccaggcca cggacgcgac cattgaattc
     2881 tttattcatg gggcactgtg cgtggcctat tcgggtcagt gctacatttc tcatgcgcaa
     2941 acagggcgta gcgccaaccg tggtgattgc tcgcaggcgt gccgtttgcc atacacattg
     3001 aaagacgatc aggggcgggt ggtttcctat gaaaaacatc tgctgtcgat gaaagataac
     3061 gatcagactg ccaacctcgg cgcgctgatt gatgctggcg tacgctcctt caagattgaa
     3121 gggcgttaca aagatatgag ctacgtgaag aatatcaccg cccattatcg ccagatgctt
     3181 gatgccatta ttgaagaacg tggcgatctg gcgcgcgctt catcaggtcg tactgaacat
     3241 ttctttgttc catcgacgga aaagactttc caccgtggta gcacagatta ttttgtgaat
     3301 gcccgtaaag gcgatattgg cgcgttcgat tcgccgaaat ttatcggcct gccggtaggc
     3361 gaagtattga aagtggcgaa agatcatctc gatgttgccg tcaccgagcc actggcaaat
     3421 ggtgatggcc tgaacgtgat gattaaacgt gaagtcgtcg gttttcgtgc caatacggtc
     3481 gagaaaaccg gagaaaatca gtaccgcgtc tggcccaatg aaatgccagc agatttgcac
     3541 aaaattcgtc cacatcaccc actaaaccgt aatcttgatc ataactggca gcaggcactg
     3601 acaaaaacct ccagcgaacg tcgggtggcg gtagacattg aactgggcgg ctggcaggaa
     3661 caactgattc tgaccctcac cagtgaagag ggtgtcagca tcacgcatac gctggacggg
     3721 cagttcgacg aagccaataa cgccgaaaaa gcaatgaaca atctgaagga tggtctggca
     3781 aaactggggc aaaccctcta ttacgcccgc gatgtgcaaa ttaatttgcc gggggcgctg
     3841 tttgtaccaa acagtctgtt aaaccagttc cgccgtgaag ctgctgacat gctggatgct
     3901 gcgcgtcttg ccagttacca gcgcggcagc cgtaaaccgg ttgctgatcc tgcgccggtt
     3961 tatccgcaaa cgcatctgag tttcctcgcg aacgtataca accagaaagc gcgtgaattt
     4021 tatcatcgct atggtgtgca gctgattgac gcggcgtatg aagcacatga agagaagggc
     4081 gaagtcccgg tgatgatcac caagcattgt ctgcgctttg cctttaatct gtgcccgaaa
     4141 caggcgaaag gcaatatcaa aagctggaag gcgacgccaa tgcaactggt taacggcgat
     4201 gaagtattaa cgctaaagtt tgattgccgc ccatgcgaga tgcacgtcat tggcaaaatc
     4261 aaaaatcaca tactgaaaat gccgttaccg ggaagcgtag tggcatccgt aagtccggat
     4321 gagctgctga aaacattgcc taagcgaaaa gggtaaaacg ccagttttct ggttactcac
     4381 aactcattga atctgcatga tattgcctgc cgggtaaggc gtctcgccgc atccggcaac
     4441 aaatgactca acgttgtccc gcttctggtt tgcgcgattt ttgccagtaa aaatgctcgc
     4501 gcaaaccttc cgccgactct tccgccacag cacgcaattc atcgctgtcc gcttcatgac
     4561 gcagctgatg atccacattc tttacccaca caaattcatg tcctttgtgc cctgccatga
     4621 gttgtcctga gaacagcgca cacgttaata agacaaccga taacgccttc gtaaacatcc
     4681 tgccaccttt ttcttacctt ttgccgctat gatgccgatc gtttcttgag gttattattc
     4741 agttttgcaa attagcgcaa agaaattctg gaatcttcct tcctgatttt gcatggcatt
     4801 ctgccgttgc ggcgatttag tgctattttc gagcaaatta cacacggagg taaacactaa
     4861 tgtttacttt gttgatatac tcagcggcag ggaggcgatg tgaaacaaag cgagttcaga
     4921 cgttggctcg aatctcaggg cgtcgatgta gcgaatggca gcaaccattt gaaactcagg
     4981 tttcatggga ggcgcagtgt catgccgcgt cacccctgcg atgagattaa agaaccattg
     5041 cgtaaagcaa tcctgaaaca actcggtttg agttaatcgc caattaaaaa ggttaatgac
     5101 atgcgaggga cagtcgaaat tatgcgttat cccgtcactc ttacacccgc gccggaaggc
     5161 ggttatatgg tttcttttgt ggatatccct gaagcgttga cgcagggcga aactgtcgct
     5221 gaagcgatgg aagcggcaaa agatgcttta ctgaccgcat ttgattttta ttttgaagat
     5281 aacgagctta tcccgttacc ttcgccatta aatagtcatg atcactttat tgaagtacct
     5341 ttgagcgtcg cctctaaagt attgctgtta aatgcttttt tacagtcaga aatcactcag
     5401 caagagttag ccaggcgaat tggcaaacct aaacaggaga ttactcgcct atttaacttg
     5461 caccatgcga caaaaatcga cgccgtccag cttgcggcaa aggcgcttgg caaagagtta
     5521 tcgctggtga tggtttaatt acagttaacg aaaagttgtc atttttaaca actgatatag
     5581 actgccgaat catctgcaca taattacgat tcgataatga aaaaatacca gcagcttgca
     5641 gaacaattac gcgagcagat tgcgtcgggt atctggcaac ccggcgatcg tttgccttcg
     5701 ttgcgtgacc aggtggcgct ttcaggcatg agctttatga ctgtcagcca tgcctatcag
     5761 ttgctcgaaa gtcagggata tattatcgca cgaccgcagt cgggttatta cgttgcgcca
     5821 caggcaataa aaatgccgaa agcgccagtc attccagtca ctcgagatga agcagtcgat
     5881 atcaacactt atatttttga tatgttgcag gccagtcgcg atccgtcggt cgttccgttt
     5941 gcctcggcct ttcccgaccc gcgacttttc cccctccaac aactaaaccg ctcgctggcg
     6001 caggtaagca aaaccgccac ggcgatgagc gtgattgaaa acttaccgcc aggaaacgca
     6061 gaactgcgtc aggctattgc tcgtcgctat gccttacagg gcatcaccat ttctcctgat
     6121 gaaattgtca ttactgccgg ggcgttagag gcattaaacc tcagtttgca agcggtaact
     6181 gaaccgggcg attgggtgat agtagagaat ccttgtttct atggcgcgtt gcaggcgctg
     6241 gaacggctac ggctgaaagc gttatcggtg gcgacggatg ttaaagaagg gatagatctt
     6301 caggcgttgg aactggcgtt gcaggagtat ccggtgaaag cgtgctggct gatgactaat
     6361 agccagaatc cactcggatt taccttaacg ccgcaaaaaa aagcacaact ggtggcgtta
     6421 ctcaatcagt acaacgtaac gctgattgaa gatgacgttt acagcgaact ttattttgga
     6481 cgggaaaaac cgctgcctgc gaaagcgtgg gatcgccacg atggcgtttt gcattgctct
     6541 tcgttttcga aatgtctggt gcctggtttt cgtattggtt gggtcgccgc cggaaaacat
     6601 gcacgtaaaa ttcaacgctt gcagttgatg agtacgcttt ccaccagctc accgatgcag
     6661 cttgcgctgg tggattacct ttccacgcgc cgatacgacg cccatcttcg tcgcctgcgt
     6721 cgccagcttg cggaacgtaa acaacgtgcc tggcaggcac tgctgcgtta tctgcctgcg
     6781 gaagttaaaa ttcatcatag tgacagcggt tattttctct ggctggagct ccccgagccg
     6841 ttagatgccg gcgaattaag cctggcggca ctgacgcatc atatcagtat tgcgccgggt
     6901 aaaatgtttt ctaccggtga aaactggtca cgtttttttc gttttaatac cgcgtggcag
     6961 tggggagaac gtgaagaaca ggcggtaaaa caattaggca aacttattca agaacggctg
     7021 taatagcgtt taatttaatt cctcttagat tgggtaatat gaatttcgaa tagcagtcat
     7081 atttcctaac cccttgtcta tactccagaa gataacctta cagacggcat aatgcgcggt
     7141 agctcacaac ctgattaaat tttctcaggg gcgaaggtgt gcctgcaagc cgccgtctat
     7201 ggttaaacaa ggagatattt ttacggcacg gcggctgaac aattaattac gacaggagta
     7261 agaccttatg agcaagacat ttgcccgcag cagcctgtgt gcgctcacca tgacaataat
     7321 gaccgctcac gccgccgaac cacctaccaa tttagataaa ccggaagggc gactggatat
     7381 tatcgcctgg ccgggataca tcgaacgcgg acaaactgat aaacaatacg actgggtaac
     7441 gcaatttgaa aaagagacag gctgcgcggt gaatgtgaaa accgccgcga cttccgatga
     7501 aatggtcagt ctgatgacca aagggggtta cgatctggtt acggcatccg gcgatgcctc
     7561 gctgcgtttg attatgggca aacgcgtgca gccgattaat accgccttga ttcccaactg
     7621 gaaaacgctc gatccgcgcg tggttaaagg cgactggttt aatgttggcg gcaaagttta
     7681 cggcacacct taccaatggg ggccgaacct gctgatgtac aacactaaaa ccttcccgac
     7741 gccgccggat agctggcaag tggtttttgt tgagcaaaat ctgccggacg gcaagagcaa
     7801 taaaggccgc gttcaggctt atgatggccc tatctacatt gcggacgctg cgttgttcgt
     7861 taaagccact cagccgcagt tgggcatcag cgatccgtat caactcaccg aagaacagta
     7921 ccaggcggtg ctgaaagtgc tgcgcgctca acacagtttg atccatcgct actggcatga
     7981 cactaccgtg caaatgagcg atttcaaaaa cgagggtgtg gttgcttcca gtgcctggcc
     8041 ctatcaggcc aacgccctga aagccgaagg ccagcctgtt gctaccgttt tcccgaagga
     8101 gggggttacc ggttgggctg ataccaccat gctgcatagc gaagcgaaac atccggtttg
     8161 cgcctacaaa tggatgaact ggtcattaac gccaaaagtg cagggcgatg tggcggcctg
     8221 gtttggctcg ttaccggtag tgccggaagg gtgtaaagcc agtccgttat taggcgaaaa
     8281 aggttgtgaa accaacggtt ttaactattt cgacaaaatc gccttctgga aaacgcctat
     8341 agcagaaggg ggcaagtttg ttccctacag tcgctggacg caggattaca ttgccattat
     8401 gggcggtcgc taacttcgct ggggtgcttt atgacgtacg cagtggagtt tgacaacgtc
     8461 tcgcggttgt acggtgacgt gcgcgcagta gatggcgtca gtattgcgat aaaagatggt
     8521 gagttcttct ctatgctggg gccgtccggc tccggcaaaa ccacctgcct gcgcctgatt
     8581 gctggcttcg aacagctttc cggcggggct atctctatct ttggtaaacc cgccagcaat
     8641 ctgccaccgt gggagcggga cgtgaatact gtctttcagg actacgcgct atttccgcat
     8701 atgtcgattc ttgacaatgt cgcctatggg ctgatggtca aaggcgtgaa taaaaagcag
     8761 cggcacgcaa tggcgcaaga ggcgctggag aaagtggcgt tggggtttgt acatcaacgt
     8821 aaaccgtcac aactttctgg tggtcagcgc cagcgggttg ctatcgccag agcattggtg
     8881 aatgaaccgc gcgtattgct gttggatgaa ccgctcggcg cactggatct caaattgcgt
     8941 gagcagatgc agctggaact gaaaaaactg caacagtctc tcggtatcac ttttatcttc
     9001 gttacccacg atcagggcga agcgttatcg atgtccgatc gtgtggcggt tttcaataat
     9061 ggacgcattg agcaggtcga ttccccgcgc gatctctata tgcgcccgcg cacgccgttt
     9121 gttgccggat tcgtcgggac atccaacgtt tttgatggac tgatggcaga gaaactttgt
     9181 ggcatgacgg gaagcttcgc cctgcgaccg gaacatatcc gcctcaacac ccctggtgaa
     9241 ctgcaggcca atggcacgat ccaggcggtg caatatcagg gcgcggcaac tcgttttgaa
     9301 ctgaaattga acggcggtga aaaactgctt gtgagtcagg ccaatatgac aggcgaagaa
     9361 ctgcctgcca cgctcacgcc cggacaacag gtgatggttt cctggtcgcg tgatgtcatg
     9421 gtgccgctgg ttgaggagag gtgaatggcg atgaatgtat tgcaatcacc ttcacgtcca
     9481 ggtctgggta aggtgtccgg tttcttctgg cgtaatccgg ggctggggct gtttttactg
     9541 ctgcttggcc cgctaatgtg gtttggcatt gtttatttcg gctcgctgct aacgctgtta
     9601 tggcagggct tttatacctt tgacgatttc accatgtcgg taacgccgga actgacgctg
     9661 gcgaatattc gtgcgctgtt taatccggcg aattacgaca tcattctccg cacgctgact
     9721 atggctgtgg cagtcactat cgccagcgcc attctggctt ttccaatggc gtggtatatg
     9781 gcgcgctata ccagcgggaa aatgaaagcg tttttttata ttgcggtaat gttgccgatg
     9841 tgggcgagct acattgttaa agcctatgcc tggacgttat tgctggcaaa agatggcgtg
     9901 gctcagtggt ttttacaaca tcttgggctg gaaccactgc tgactacgtt ccttacatta
     9961 cctgcggtgg gcggcaatac gctgtcaact tccgggctgg ggcgctttct ggtgtttctc
    10021 tatatctggc tgccgttcat gatcctgccc gtgcaggcgg cgcttgagcg tttgccgccg
    10081 tcattgttgc aggcgtcggc tgatctcggc gcacgtccac gacaaacctt tcgctatgtg
    10141 gtgctgccgc tggcaatccc gggtattgcc gctggctcta tctttacctt ctcactcaca
    10201 ctgggcgatt ttatcgtccc gcagctggtt ggtcctccag gatattttat cggcaatatg
    10261 gtttattccc agcagggggc gattggcaat atgccgatgg cggcggcatt caccctggtg
    10321 ccgattgttc tcatcgcact gtacctggcg ttcgtgaaac gtctgggagc gttcgatgca
    10381 ctctgaacgc gcaccgtttt tcctcaaact ggcggcctgg ggcggcgttg ttttcctaca
    10441 ttttcccatc ctgataatcg ccgcctatgc gtttaacact gaagatgcgg cgtttagttt
    10501 tccaccgcag ggcctgacgc tgcgctggtt tagcgtggca gcacggcgta gtgatattct
    10561 tgatgccgtg acactgtcac ttaaagtggc ggcgctggcg acattaattg cgctggtgtt
    10621 agggacgctg gcagctgccg cgctgtggcg acgagacttt ttcggcaaaa acgccatttc
    10681 gctgttactg ctgctgccca ttgcgctgcc gggcattgtc actggtctgg cgctattaac
    10741 cgcttttaaa accatcaatc tggagccggg atttttcacc atcgtggtcg gtcatgcgac
    10801 tttttgcgta gtggtggtgt ttaacaatgt catcgcccgt tttcgccgca cctcgtggag
    10861 tctggttgag gcgtcaatgg atcttggggc caatggctgg caaaccttcc gctacgtagt
    10921 gttgccgaat ctcagttcgg cgctactggc aggaggaatg ctggcgtttg ccttgtcgtt
    10981 cgatgaaatc atcgttacga cttttacggc aggtcatgaa cgaacgttac cgttgtggtt
    11041 gctcaatcag cttgggcgac cgcgtgatgt accggtaact aacgtggtgg cactgctggt
    11101 tatgttggta acaaccttgc cgatcctggg ggcctggtgg ctaacccgcg aaggcgacaa
    11161 tggtcaataa ccactgatac aggaatatgc tatgcaacat aagttactga ttaacggaga
    11221 actggttagc ggcgaagggg aaaaacagcc tgtctataat ccggcaacgg gggacgtttt
    11281 actggagatt gccgaggcat ccgcagagca ggtcgatgct gctgtgcgcg cggcagatgc
    11341 agcatttgcc gaatgggggc aaaccacgcc gaaagtgcgt gcggaatgtc tgctgaaact
    11401 ggctgatgtt atcgaagaaa atggtcaggt ttttgccgaa ctggagtccc gtaattgtgg
    11461 caaaccgctg catagtgcgt tcaatgatga aatcccggcg attgtcgatg tttttcgctt
    11521 tttcgcgggt gcggcgcgct gtctgaatgg tctggcggca ggtgaatatc ttgaaggtca
    11581 tacttcgatg atccgtcgcg atccgttggg ggtcgtggct tctatcgcac cgtggaatta
    11641 tccgctgatg atggcagcgt ggaaactggc tccggcgctg gcggcaggga actgcgtagt
    11701 gcttaaacca tcagaaatta ccccgctgac cgcgttgaag ttggcagagc tggcgaaaga
    11761 tatcttcccg gcaggcgtga ttaacgtact gtttggcaga ggcaaaacgg tgggtgatcc
    11821 gctgaccggt catcccaaag tgcggatggt gtcgctgacg ggctctatcg ccaccggcga
    11881 gcacatcatc agccataccg cgtcgtccat taagcgtact catatggaac ttggtggcaa
    11941 agcgccagtg attgtttttg atgatgcgga tattgaagca gtggtcgaag gtgtacgtac
    12001 atttggctat tacaatgctg gacaggattg tactgcggct tgtcggatct acgcgcaaaa
    12061 aggcatttac gatacgctgg tggaaaaact gggtgctgcg gtggcaacgt taaaatctgg
    12121 tgcgccggat gacgagtcta cggagcttgg acctttaagc tcgctggcgc atctcgaacg
    12181 cgtcagcaag gcagtagaag aggcgaaagc gacagggcac atcaaagtga tcactggcgg
    12241 tgaaaagcgc aagggtaatg gctattacta tgcgccgacg ctgctggctg gcgcattaca
    12301 ggacgatgcc atcgtgcaaa aagaggtatt tggtccagta gtgagtgtta cgcccttcga
    12361 caacgaagaa caggtggtga actgggcgaa tgacagccag tacggacttg catcttcggt
    12421 atggacgaaa gatgtgggca gggcgcatcg cgtcagcgca cggctgcaat atggttgtac
    12481 ctgggtcaat acccatttca tgctggtaag tgaaatgccg cacggtggac agaaactttc
    12541 tggttacggc aaggatatgt cactttatgg gctggaggat tacaccgtcg tccgccacgt
    12601 catggttaaa cattaaggat aatattgcag atcgtaagag tatgagatga tcttgcgtac
    12661 tgtcagagag ttgatttctc tgacagtacg tgctgcgtgc aaaatcacta catcaaataa
    12721 accagccaaa tctcatagag ataagagtaa acaaaccaac agcagcaaag acatttatca
    12781 gtactacagt tctactggaa acattcattt ttgccacctt ttatcattgc ccctatgtgt
    12841 atagtacggg ttaagaaaat ccgcaataat actcattctg aagatggata agggcaagtt
    12901 gctgtttgat gattttttct caaactggtg aaaaaacttg atgcacgtca aaaaatgacg
    12961 catatttgcg cgcgttttat tcatctggct ggacgcccgt acatgtctct ctatcaacat
    13021 atgcttgttt tttatgcggt tatggcagca atcgcatttc ttatcacctg gtttctttct
    13081 cacgataaga aacgcatccg tttcttaagc gcctttctgg tgggggcaac atggccgatg
    13141 agtttcccgg tggcgctgtt gttttcactg ttttaaatct tactcactgg cttgacggca
    13201 ccacgcagac ttatatcatt tggatgaatc gataaatttc acaagtggtt aaggagaaag
    13261 tatgtcgcat ctggatgaag tcatcgcgcg cgtggatgcc gcgattgaag agagcgtcat
    13321 tgcccatatg aacgaattat taatcgccct gagcgatgac gcggagttaa gtcgggaaga
    13381 tcgctacacc cagcagcagc gtttgcgcac cgctattgct catcacggtc gcaagcataa
    13441 agaagatatg gaagcgcgcc acgaacagtt aaccaaaggc ggcaccatcc tctgattaaa
    13501 atgagcgtct ggctaccaac caggcgccaa ccacaagtaa aattgcgcca caaattgggc
    13561 cgaacaacgc ccgtagtggt acgccatgac tgcggaagat atccagcatc agaccgccaa
    13621 ttagctggct ggcgaccagt actgcaatag ttgtcgccgc tcccacattc tgatatccgc
    13681 tgatactggc gaagacaaaa aacgatccca gcaagccggg tataagtgtc caccagcgca
    13741 cgctggacac cagttcgcca aaccccgcca tgccttgttt aaaccataaa atagaaacaa
    13801 agagcacaat ccccaccagt gagttcagca acatggcgat gagaatggta gaggaggtct
    13861 gggtgatgcg caccatcagc gtgttctgga ctaccagacc aattccggcg gcaatcaaaa
    13921 aagcaagggt gagcgactga ttcatccaat cgcgtccggt tcagtgcgtt cgtcgagttg
    13981 caactgcata aatgtcagat ccagccagcg cccaaattta gtgcccacct gcggcatttg
    14041 tgcggtgacg acaaatccca gcgaatggtg cagatgcagc gaggcctgat tttgcgattc
    14101 gatcccggcg accatgacat gcttcccgca atcccgcgct tcatcaatca atcggcttaa
    14161 caatttacgc cccagacctt tgccctgatg atcgggatgg acataaaccg aatgttccac
    14221 ggtatggcga aaaccatcga aactacgcca gtcgccaaac gaggcatatc ccgtcactac
    14281 gccatcttct tcactcacca gcaccggata acctgctatg gtccgcgctt caaaccaggc
    14341 aatgcggtta tctgcatcaa ccgtttggtc attccagata gccgccgtat acaacacggc
    14401 gtggttataa atttccgcaa tggcagcaca atcggctttg cgggcaaaac ggatggacat
    14461 gtctggcctc gataaaataa tgatgatgat gttatcaata ctatcgaaaa cagcccgaag
    14521 caacggattc ctcgatgaaa ttattgcgtg ttgcagaggg gatgtgacgg ctgcaaacaa
    14581 aactaatccc gtgagcctgc tactattgat ggattcatgc caaaagcaca ggagagcatt
    14641 atggggcaac aaaagcagcg taatcgacgt tgggttctgg cctcgcgtcc acatggcgca
    14701 ccggttccgg agaatttccg tcttgaagaa gatgatgtcg ccacaccggg tgaaggacag
    14761 gtgttactgc gcacagttta tttgtccctg gacccgtata tgcgtggacg tatgagcgat
    14821 gagccatctt attcaccgcc tgttgatatt ggcggcgtga tggtcggcgg cacggtgagc
    14881 cgtgttgtgg agtcgaatca tcctgattat cagcctggcg actgggtgct gggctacagt
    14941 ggatggcagg actatgacat atccagtggt gatgatctgg tgaaacttgg cgatcatccg
    15001 caaaatccat cgtggtcgct gggtgtgctg gggatgccag gctttaccgc ttatatgggg
    15061 ctgctggata tcggtcagcc taaagagggc gaaacgttgg tggtagctgc ggcgacaggt
    15121 cctgtgggag caacggtggg gcaaatcggc aaacttaaag gttgcagggt ggtgggggtt
    15181 gccggtggcg cggaaaaatg ccgccatgct atcgaggtgc tgggcttcga tgtttgtctt
    15241 gatcaccacg cggatgattt tgccgaacaa ctggtgaaag cgtgcccaaa aggtattgat
    15301 atctattatg aaaacgtggg cggtaaggta tttgatgcag tgctaccatt acttaataca
    15361 tctgcgcgca ttcccgtttg tggcttagtg agcagctata acgctacaga gctaccaccc
    15421 ggtccggatc gtttacccct gttgatggca acggtgctga aaaaacgtat tcgcttgcaa
    15481 gggtttatta tcgctcagga ttatggtcac cgcatccatg agtttcagaa ggagatgggg
    15541 caatgggtga aagaggataa aatccactac cacgaagata ttactgatgg tttagagaat
    15601 gcgccacaga cgtttatcgg cctgctgaag ggtaaaaact tcggcaaagt ggtgatccgc
    15661 gtcgcgggtg atgattaaag tttcaacggc ggcgtaagcc gccataaaaa tccaggcaaa
    15721 aagcttattt tcagctttaa ttaactaacc acgtcattgt tctgctgcta ataacaacaa
    15781 aggtgggtgg tttatgatta ttcactttaa tacaccaggt gaactccttc tgccgtgcag
    15841 gcagggttgg acagaaaaca cgcgaaggaa ttaaaatgcc tggaatggga aaaatgaaac
    15901 atgtcagttt gactctgcag gttgagaacg acctgaaaca tcagcttagt attggcgcat
    15961 taaaacctgg cgcacgcctg attactaaaa atctggcgga gcaattaggt atgagtatta
    16021 cacctgtgcg tgaagcatta ttacgtctgg tttcggtgaa tgcgctttct gtcgcacctg
    16081 cacaagcatt tacagttccg gaagtgagga aacgtcaatt agacgaaatc aatcggatcc
    16141 gctacgaact ggaattaatg gcagttgctc tggctgttga aaacctcacc ccgcaagacc
    16201 tggcggaact ccaggaattg ctcgagaaat tacagcaggc gcaagaaaag ggcgacatgg
    16261 aacaaatcat taatgtaaac aggctatttc gcttagcgat ttatcatcgc tcaaatatgc
    16321 ccatcctgtg tgagatgatt gagcaactgt gggtcaggat ggggcctggt ttacattatc
    16381 tctatgaagc gattaatcca gcggaattac gggagcatat agaaaactat catctgttac
    16441 tcgctgcgtt aaaagcaaaa gacaaagagg gatgcagaca ttgtcttgct gaaattatgc
    16501 aacaaaatat tgctatttta taccagcaat acaatcgtta aagtaaatgc ccggcaaata
    16561 ccgggcatca aggtaattac tcaaatctcc acgcaatatt catgccgaca ccataatttc
    16621 gtccgggcga aggttcgtaa tatcgcccgt ttgactcatt gacaatgaca gaaccaacgt
    16681 attctttatc gaataaatta tcgacacgac caaataaatc cacagttaaa ttgtggtaat
    16741 tgtatttata cccggtgaat aagccgacga gagtataaga cggcgctttt gccgtatttt
    16801 catcatctgc cataatatcg cccatataac gcgcttccgt gcctgcatac caaccatctt
    16861 ccggtacata acctatcgac gcaaagccca tattacgggc gatccctggc atccgattac
    16921 cgttacaatc ctgttcattg caaacattgc tgcgataggt cgcatcaagc caggtccagg
    16981 acgcgtttac gcgaaaatct cctgcgaaac gttgatccca tgccagttca gcgccttgac
    17041 gacgggtctt tccggcattt ttgtaagtcg tacgcccacc gctactgcta tcgacaacaa
    17101 tttcatcatc agtgtcggtc tgaaacaatg cgagactaag cagcccatca ccaatacgcg
    17161 ttttactgcc gatctcaatt gtatcgttgg tggatggttt taaaccaaag ttcataccgc
    17221 tttgcccatc agcacgataa gacagctcat taatcgtcgg cgtttcaaaa cctcgcccgg
    17281 ctgccagata gatattccag gcatcggtca ttgcatattt taacgaaccg gcaggtagcc
    17341 atttatgata actggcatca ccgctgtcat cgccgttacc cggagtaacg taatggtcgt
    17401 tggaatcaaa ccacacggag ctgtagcgca cgccagcatc cagcgacagt ttttcgctca
    17461 gctgccactg cgtctgtaaa tagggatcga tgttccacat cagattgcgt tcgtcgcgac
    17521 gcaactcacc tttttgcccg tactccggca tgccgctatt caggcggaag ttattgtagc
    17581 ccttgcggtt ttcactcatg ttttcgtagt tcaggccggt agtgaacgtg accggaacgc
    17641 ccagttcacc acggtgtgtc cagcggctgt ctatcccctg gtaatggcgt tgcagggtaa
    17701 tcacgccgcc cgcatgtgac gggttaagtt ggggggccat cgggattgac tggtactggg
    17761 tcgtttctcg ctctccggca tacatcatca cactcatatc atcttgcgcg ctcaggctac
    17821 gctcatagcg caacccagcc tgagtttgct tgatggtttt tcgcgtgtcg tactgttctg
    17881 cacgaggcgc ttgttgtgga ttagccttcc attctgcttt ggttagccca cctgggtcat
    17941 ctgctttgat atccacacta ttgaaaatca gacttaattt gctggcttca tcaatgcgta
    18001 cgcccagttt ggcattagct aaatttttct gtgcgccact atggtcacga tagccgtggg
    18061 tcgtaaaacg cgtggttgag acggtgtaat cgacatcgcc aggctgtgtg ccgtctcccg
    18121 ttgcgcccgt tgctttcagc ccatagcgcc agctgccaaa actgccgtag taactactgg
    18181 cttcaatggt tggtggctgt tgtccggtct gggtggtgac attcattacc ccaccagacg
    18241 cgttgccata cagggcagag aaggggccac gcagcacttc cacattttgc acactgctta
    18301 aatcgatgtt ggatgtttgc ccttgcccgt cgggcatggt ggcgggaata ccgtccacat
    18361 acaggcgaat accgcgaata ccgtaagtgg agcgggagcc aaatccgcga atcgacagct
    18421 gtaaatcttg cgcatagttc tgccggtttt gtacctgcaa accaggcacg ccggtcagtg
    18481 attcggacaa gttaatgcgc ggtgttgcca ggcgcatctc ctcgccatcc accacgctta
    18541 ctgctgctgg ggtatccagt tctgaaacca cctgcggtgc ggcactgaca atcatagtct
    18601 gttcatcagc ggcaaaaaca acgggggaaa ggacaagcag tgcgggcaaa acggtctgtc
    18661 ggacggaaaa aatcttcatg aaaaaagcca ggttaagaat gggaaaacgc cgttatggta
    18721 atgaaattgt aaatttatgg aaaacgaaac ggcacgatac gttaagtaat tgagaaaatt
    18781 gtagtcgtaa cggcaagaaa tgctccacat ttgagaaaat aatgattacc attcccattt
    18841 ataacaagag cgtaacgatg attacgctta gcgaagcatt gtgaagcagc aaaaatatcg
    18901 gttcatcaaa gggagtcgtc atgcatttac gtcatctgtt ttcatcgcgc ctgcgtggtt
    18961 cattactgtt aggttcattg cttgttgctt catcattcag tacgcaggcc gcagaagaaa
    19021 tgctgcgtaa agcggtaggt aaaggtgcct acgaaatggc ttatagccag caagaaaacg
    19081 cactgtggct cgccacttcg caaagccgca aactggataa aggtggcgtg gtttatcgtc
    19141 ttgatccggt cactctggaa gtgacgcagg cgatccataa cgatctcaag ccgtttggtg
    19201 ccaccatcaa taacacgact cagacgttgt ggtttggtaa caccgtaaac agcgcggtca
    19261 cggcgataga tgccaaaacg ggcgaggtga aaggccgtct ggtgctggat gatcgtaagc
    19321 gcacggaaga ggtgcgcccg ctgcaaccgc gtgagctggt agctgatgat gcctcgaaca
    19381 ccgtttacat cagtggtatt ggtaaagaga gcgtgatttg ggtcgttgat ggcgagaata
    19441 tcaaactgaa aaccgccatc cagaacaccg gtaaaatgag taccggtctg gcgctggata
    19501 gcaaaggcaa acgtctttac accactaacg ctgacggcga attgattacc atcgacaccg
    19561 ccgacaataa aatcctcagc cgtaaaaagc tgctggatga cggcaaagag cacttcttta
    19621 tcaacattag ccttgatacc gccaggcagc gtgcatttat caccgattct aaagccgcag
    19681 aagtgttagt ggtcgatacc cgtaatggca atattctggc gaaggttgcg gcaccagaat
    19741 cactggctgt gctgtttaac ccagcgcgta atgaagccta cgtaacgcat cgtcaggcag
    19801 gtaaagtcag tgtgattgac gcgaaaagct ataaagtggt gaaaacgttc gatacgccga
    19861 ctcatccaaa cagcctggcg ctgtctgccg atggcaaaac gctgtatgtc agtgtgaaac
    19921 aaaaatccac taaacagcag gaagctaccc agccggacga tgtgattcgt attgcgctgt
    19981 aatagatgtg gcgagggtga aaacggagag acttgcctga cttttattac gccgcatgcg
    20041 gcacaccttc gtcagtaatc taaatttgcc cggcacgtag ccgggcaatt ttgcaattag
    20101 ctcgccgttt caggcttaaa cacaatttcc tgtttttctt catcttcctc gacgactggc
    20161 gcagtgctgt gaatttcagc aacgcgtttg cgcacaccaa accagcctat aaccagcaga
    20221 ataccgataa tcggcagcgc cgcgatagta taagtcccgt tcgggtaatc gaacgccatc
    20281 agcaccagga cactcagtaa aaacagtaat gtcagccagg aagtgaaggg cgcgccaggc
    20341 agtttaaaac tgacatccgc tgctttgcct tgtttaattg ctttacgcag gcgcatctgg
    20401 cacacgatga taaacgccca tgaagcgatg attcccagcg acgcgaagtt caacacaatc
    20461 tcaaatacgc gcgacggcac cagatagttg aggaatacgc cgacgacata cacaactagt
    20521 gtcgccagaa tcccggcata cggcacatgc tgacgactca ttttcgccat aaaactcggt
    20581 gcggaaccgc ccatcgccat tgagcgcaga atacgtccgg tgcagtacag acctgagttc
    20641 aggctggaga gggcagcggt cagcaccaca atgttcataa tgctgccgat atatggcaca
    20701 cccagtttag agaaaaacgt cacgaacgga ctttgccccg cctgatacgc gctccacggc
    20761 aatagcataa ccagcaacac cacggagccg acgtaaaaca ggccaatacg ccaaatcacg
    20821 ctgttaatcg ctttaggcac catggtctgc ggatctttac attctccggc agctgtaccc
    20881 accatttcaa tggaggcaaa agcaaacact acgccctgaa tcaacaccag agcaggcagc
    20941 aaaccgtggg ggaagaagcc gccattatcg gtaattaaat gaaagccagt ggtgttgcca
    21001 tccagcggct gaccactacc gaggaacact gtacccacga ccaaaaaggt cacaatggcg
    21061 agcactttaa taagcgcaaa ccagaactcc atctccgcaa accatttcac accgatcata
    21121 ttcatggtgc caacgatggt aagtgcagcg agcgcaaaga cccactgcgg cacgccgcca
    21181 aacgcacccc agtaatgcat atacagagcg acggcggtaa tatcaacaat ccccgtcatc
    21241 gcccagttga tgaagtacat ccagccagca acataagcgg ctttctcacc caaaaactca
    21301 cgggcataag agacaaaact gccactggaa gggcggtgta gcaccagctc acccaatgca
    21361 cgcagaataa aaaacgaaaa caagccacaa attaaataaa ccagtgccaa tgctggaccc
    21421 gccatttgca gtcgggctcc tgcacctaaa aacaagccgg tgccaatcgc gccgccaatg
    21481 gcgatcatct gtacctggcg attgcccatc gctttgtgat acccctcttc gtgggcatta
    21541 agccagcggc gtttcgcggc gtgttgatct gaagtgtcgg tgtcgtgttt actcattgct
    21601 ctccctgatt gctttaatga aaaagtcata taagttgcca tgaacaatgt ttattcatcc
    21661 tggcgatgat agttatcacc attattcttt atgggtataa aactatcggc gcagcatcct
    21721 acccgttatc gataaacgat gcaaaacatc cccttacaat cctgaagggg aataatacaa
    21781 ctgacgaaaa aatgacaaat ctttttgctg gttaacctgt gtactgtcct acacttaatc
    21841 tttaaaagat tgtgagggca tatgattaag gtgtatggcg tacccggatg gggctctaca
    21901 atcagtgagc tgatgctaac actggctgat attccttatc agttcgttga tgtcagtggt
    21961 tttgaccacg agggagcttc acgcgagtta ttgaaaaccc tgaacccgtt gtgtcaggtt
    22021 ccgacactgg cgctggaaaa tgacgagatt atgacggaga cagcggcgat tgcatttatg
    22081 gttctcgatc gtcgcccgga ccttgcgcca ccggttgggc gcgccgaacg tcagcagttt
    22141 caacggctat tggtctggct ggttgctaat gtctatccaa cattcacttt cgccgattac
    22201 cctgagcgtt gggcatctga cgcacctgaa cagttaaaga agaatgtaat tgaatatcgc
    22261 aaatcacttt atatctggct gaattcacaa ttgaccgctg aaccttatgc ctttggtgag
    22321 caactaacgc tggtggactg ttatctctgc accatgcgca catgggggcc ggggcatgaa
    22381 tggtttcagg ataatgcgca gaatatcagc gcgatcgctg atgctgtatg tcagttaccg
    22441 aaattacaag aagtattaaa
//
LOCUS       DAPGUL010000072        22423 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.073, whole genome shotgun sequence.
ACCESSION   DAPGUL010000072 DAPGUL010000000
VERSION     DAPGUL010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22423
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.073"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..324
                     /locus_tag="RHX21_002963"
     CDS             <1..324
                     /locus_tag="RHX21_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019725197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDV1988116.1"
                     /translation="PWGRCDVVVQTPRFNVNRITVKPGGAFSMQMHHHRAEHWVILAG
                     TGQVTVNGKQFLLSENQSTFIPIGAEHCLENPGCIPLEVLEIQSGAYLGEDDIIRIKD
                     QYGRC"
     gene            348..1730
                     /gene="rfbK2"
                     /locus_tag="RHX21_002964"
     CDS             348..1730
                     /gene="rfbK2"
                     /locus_tag="RHX21_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_166649022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O9 family phosphomannomutase RfbK2"
                     /protein_id="HDV1988117.1"
                     /translation="MTQLTCFKAYDIRGELGEELNEDIAYRIGRAYGEFLKPGKIVVG
                     GDVRLTSESLKLALARGLMDAGTDVLDIGLSGTEEIYFATFHLGVDGGIEVTASHNPM
                     NYNGMKLVRENAKPISGDTGLRDIQRLAEENQFPPVDPARRGTLSKISVLKEYVDHLM
                     SYVDFSNFTRPLKLVVNSGNGAAGHVIDEVEKRFAAAGVPVTFIKVHHQPDGHFPNGI
                     PNPLLPECRQDTADAVREHQADMGIAFDGDFDRCFLFDDEASFIEGYYIVGLLAEAFL
                     QKQPGAKIIHDPRLTWNTVDIVTRNGGQPVMSKTGHAFIKERMRQEDAIYGGEMSAHH
                     YFRDFAYCDSGMIPWLLVAELLCLKNSSLKSLVADRQRAFPASGEINRKLRNAAEAIA
                     RIRAKYEPAAAHIDTTDGISIEYPEWRFNLRTSNTEPVVRLNVESRADVALMNEKTTE
                     LLNLLKEELL"
     gene            1736..2521
                     /locus_tag="RHX21_002965"
     CDS             1736..2521
                     /locus_tag="RHX21_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001310941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O9 family O-antigen ABC transporter permease
                     subunit Wzm"
                     /protein_id="HDV1988118.1"
                     /translation="MFSAIYRYRGFIIDSVKRDFQSRYQTSFLGAAWLILQPIAMISV
                     YTLIFSELMRARLAGMDGPFAYSIYLCSGVLTWGLFTETLNSLVNVFLTNANILKKLS
                     FPRICLPIIVTASAFINFLIIFGLFVLFLIVTGNFPGMIFFEIIPVLIVQMLFTLGLG
                     IILGVLNVFVRDVGQFVNILLQFWFWFTPIVYVSKTLPEWVSGLLAYNPMATIIGSYQ
                     NVMLYHQSPNWLALLPVAVLSVILFLFAWRLFKKHAADIVDEI"
     gene            2524..3819
                     /locus_tag="RHX21_002966"
     CDS             2524..3819
                     /locus_tag="RHX21_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000025034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O9 family O-antigen ABC transporter ATP-binding
                     protein Wzt"
                     /protein_id="HDV1988119.1"
                     /translation="MSIKVQHVGKAYKYYPSKWNRVIEKLLPGDKPRHSKKWVLKDIN
                     FSIEPGEAVGIVGVNGAGKSTLLKLLTGTTQPTKGSIEIQGRVAALLELGMGFHPDFT
                     GRQNVYMSGLMMGLSREEIECLMPEIEAFADIGDYIEEPVRVYSSGMQMRLAFAVATA
                     SRPDILIVDEALSVGDSRFQAKCYARIADFKKQGTTLLLVSHSAGDIVKHCDRAIFLK
                     NGDICMDGTARDVTNRYLDELFGKPDKDSATKSATAISSASGESQMSLDEIEDVYHTR
                     PGYRPEEYRWGQGGAKIIDYHIQSAGVDFPPSLTGNQQTDFLMKVVFEYDFDCVVPGI
                     LIKTLDGLFLYGTNSFLASEGRENISVSRGDVRVFKFSLPVDLNSGDYLLSFGISAGN
                     PQTDMTPLDRRYDSIILHVTKSMDFWGVIDLKSSFTSYQ"
     gene            3839..5965
                     /locus_tag="RHX21_002967"
     CDS             3839..5965
                     /locus_tag="RHX21_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012967601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDV1988120.1"
                     /translation="MTKDLNTLVSELPEIYQTIFGHPEWDGDAARDCNQRLDLITEQY
                     DNLSRALGRPLNVLDLGCAQGFFSLSLASKGATIVGIDFQQENINVCRALAEENPDFA
                     AEFRVGRIEEVIAALEEGEFDLAIGLSVFHHIVHLHGIDEVKRLLSRLADVTQAVILE
                     LAVKEEPLYWGVSQPDDPRELIEQCAFYRLIGEFDTHLSPVPRPMYLVSNHRVLINDF
                     NQPFQHWQNQPYAGAGLAHKRSRRYFFGEDYVCKFFYYDMPHGILTAEESQRNKNELH
                     NEMCFLAQPPTGFDTPALLAHGENAQSGWLVMEKLPGSLLSDMLVAGEEIDREKIIGT
                     LLRSLAVLEKQGLWHDDVRPWNVMVDARQHARLIDFGSIVTTPQDCSWPANLVQSFFV
                     FVNELFAENKSWNGFWRSAPVHPFNLPQPWSNWLYAVWQEPVERWNFALLLALFEKKA
                     KLPSAEQQRGATEQWIIAQETVLLELQSRVLNESAGSEALRGQIHTLEQQMAQLQSAQ
                     DAFVEKAQQPVEVSHELTWLGENMEQLAALLQTAQAHAQADVQPELPPETAELLQRLE
                     AANREIHHLSNENQQLRQEIEKIHRSRSWRMTKGYRYLGLQIHLLRQYGFVQRCKHFI
                     KRVLRFVFSFMRKHPQVKHTAVNGLHKLGLYQPAYRLYRRMNPLPHSQYQADAQILSQ
                     TELQVMHPELLPPVVYEIYLKLTKNK"
     gene            5976..8498
                     /gene="wbdA"
                     /locus_tag="RHX21_002968"
     CDS             5976..8498
                     /gene="wbdA"
                     /locus_tag="RHX21_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_105458066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polymannosyl
                     GlcNAc-diphospho-ditrans,octacis-undecaprenol
                     2,3-alpha-mannosylpolymerase WbdA"
                     /protein_id="HDV1988121.1"
                     /translation="MHILIDVQGYQSESKVRGIGRSTLAMSRAIIENAGEHRVSILIN
                     GMYPIDNINDVKMAYRDLLTDEDMFIFSAVAPTAYRHIENHGRSKAAQAARDIAIANI
                     APDIVYVISFFEGHSDSYTVSIPADNVPWKTVCVCHDLIPLLNKERYLGDPNFREFYM
                     NKLAEFERADAIFAISQSAAQEVIEYTDIASDRVLNISSAVGEEFAVIDYSAERIQSL
                     KDKYSLPDEFILSLAMIEPRKNIEALIHAYSLLPAELQQRYPMVLAYKVQPEQLERIL
                     RLAESYGLSRSQLIFTGFLTDDDLIALYNLCKLFVFPSLHEGFGLPPLEAMRCGAATL
                     GSNITSLPEVIGWEDAMFNPHDVQDIRRVMEKALTDEAFYRELKAHALAQSAKFSWAN
                     TAHLAIEGFTRLLQSSQETDAGQAESVTASRLQMMQKIDALSEVDRLGLAWAVARNSF
                     KRHTRKLLVDISVLAQHDAKTGIQRVSRSILSELLKSGVPGYEVSAVYYTPGECYRYA
                     NQYLSSHFPGEFGADEPVLFSKDDVLIATDLTAHLFPELVTQIDSMRAAGAFACFVVH
                     DILPLRRPEWSIEGIQRDFPIWLSCLAEHADRLICVSASVAEDVKAWIAENRHWVKPN
                     PLQTVSNFHLGADLDASVPSTGMPDNAQALLAAMAAAPSFIMVGTMEPRKGHAQTLAA
                     FEELWREGKDYNLFIVGKQGWNVDSLCEKLRHHPQLNKKLFWLQNISDEFLAELYARS
                     RALIFASQGEGFGLPLIEAAQKKLPVIIRDIPVFKEIAQEHAWYFSGEAPSDIAKAVE
                     EWLALYEQNAHPRSENINWLTWKQSAEFLLKNLPIIAPAAKQ"
     gene            8545..9690
                     /locus_tag="RHX21_002969"
     CDS             8545..9690
                     /locus_tag="RHX21_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016809192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDV1988122.1"
                     /translation="MKIIFATEPIKYPLTGIGRYSLELVKRLAVAREIEELKLFHGAS
                     FIDQIPQVENKSDSKASNHGRLSAFLRRQPLLIEAYRLLHPRRQAWALRDYKDYIYHG
                     PNFYLPHRLERAVTTFHDISIFTCPEYHPKDRVRYMEKSLHESLDSAKLILTVSDFSR
                     NEIIRLFNYPADRIVTTKLACSSDYIPRSPAECLPVLQKYQLAWQGYALYIGTMEPRK
                     NIRGLLQAYQLLPMETRMRYPLILSGYRGWEDDVLWQLVERGTREGWIRYLGYVPDED
                     LPYLYAAARTFVYPSFYEGFGLPILEAMSCGVPVVCSNVTSLPEVVGDAGLVADPNDV
                     DAISAHILQSLQDDSWREIATARGLAQAKQFSWENCTTQTINAYKLL"
     gene            9700..10815
                     /locus_tag="RHX21_002970"
     CDS             9700..10815
                     /locus_tag="RHX21_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004184789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDV1988123.1"
                     /translation="MRVLHVYKTYYPDTYGGIEQVIYQLSQGCARRGIAADVFTFSPD
                     KETGPVAYEDHRVIYNKQLFEIASTPFSLKALKRFKQIKDDYDIINYHFPFPFMDMLH
                     LSARPDARTVVTYHSDIVKQKRLMKLYQPLQERFLASVDCIVASSPNYVASSQTLKKY
                     QDKTVVIPFGLEQHDVQHDPQRVAHWRETVGDNFFLFVGAFRYYKGLHILLDAAERSR
                     LPVVIVGGGPLEAEVRREAQQRGLSNVVFTGMLNDEDKYILFQLCRGVVFPSHLRSEA
                     FGITLLEGARFARPLISCEIGTGTSFINQDKVSGCVIPPNDSQALVEAMNELWNNEET
                     SNRYGENSRRRFEEMFTADHMIDAYVNLYTTLLESKS"
     gene            complement(10854..11462)
                     /locus_tag="RHX21_002971"
     CDS             complement(10854..11462)
                     /locus_tag="RHX21_002971"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HDV1988124.1"
                     /translation="MLTEQQRHELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDK
                     TIESGKVTFFSRTKQRLWTKGETSGNFLNVVSIAPDCDNDTLLVLANPIGPTCHKGTS
                     SCFGDTAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVNDRFELTNEASDLMYHLLVLLQDQGLDLGEVIDNLKNRH"
     gene            complement(11456..12232)
                     /gene="hisF"
                     /locus_tag="RHX21_002972"
     CDS             complement(11456..12232)
                     /gene="hisF"
                     /locus_tag="RHX21_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HDV1988125.1"
                     /translation="MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYAEEGA
                     DELVFYDITASSDGRVVDKSWVSRVAEVIDIPFCVAGGIKSLDDAAKILSFGADKISI
                     NSPALADPTLITRLADRFGVQCIVVGIDTWYDAETGKYHVNQYTGDESRTRVTQWETL
                     DWVEEVQKRGAGEIVLNMMNQDGVRNGYDLEQLKKVREVCHVPLIASGGAGTMEHFLE
                     AFRDADVDGALAASVFHKQIINISELKAYLATQGVEIRIC"
     gene            complement(12214..12951)
                     /gene="hisA"
                     /locus_tag="RHX21_002973"
     CDS             complement(12214..12951)
                     /gene="hisA"
                     /locus_tag="RHX21_002973"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416528.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HDV1988126.1"
                     /translation="MIIPALDLIDGTVVRLHQGDYGKQRDYGNDPLPRLQDYAAQGAE
                     VLHLVDLTGAKDPARRQIPLIKTLVAGVNVPVQVGGGVRSEEDVAALLEAGVARVVVG
                     STAVKSPEMVKVWFERFGADALVLALDVRIDEQGNKQVAVSGWQENSGVSLEQLVETY
                     LPVGLKHVLCTDISRDGTLAGSNVSLYEEVCARYPQVAFQSSGGIGDIDDVAALRGTG
                     VRGVIVGRALLEGKFTVKEAIACWQNA"
     gene            complement(12951..13541)
                     /gene="hisH"
                     /locus_tag="RHX21_002974"
     CDS             complement(12951..13541)
                     /gene="hisH"
                     /locus_tag="RHX21_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HDV1988127.1"
                     /translation="MNVVILDTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFL
                     PGVGTAQAAMDQVRERELFDLIKACTQPVLGICLGMQLLGRRSEESNGVDLLGIIDED
                     VPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYG
                     EPFTAAVQKDNFYGVQFHPERSGAAGAKLLKNFLEM"
     gene            complement(13541..14608)
                     /gene="hisB"
                     /locus_tag="RHX21_002975"
     CDS             complement(13541..14608)
                     /gene="hisB"
                     /locus_tag="RHX21_002975"
                     /EC_number="3.1.3.15"
                     /EC_number="4.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310850.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     histidinol-phosphatase/imidazoleglycerol-phosphate
                     dehydratase HisB"
                     /protein_id="HDV1988128.1"
                     /translation="MSQKYLFIDRDGTLISEPPSDFQVDRFDKLAFEPGVIPQLLKLQ
                     KAGYKLVMITNQDGLGTQSFPQVDFDGPHNLMMQIFTSQGVQFDEVLICPHLPADECD
                     CRKPKVKLVERYLAEQAMDRANSYVIGDRATDIQLAENMGINGLRYDRETLNWPMIGE
                     QLTKRDRYAHVVRNTKETQIDVQVWLDREGGSKINTGVGFFDHMLDQIATHGGFRMEI
                     NVKGDLYIDDHHTVEDTGLALGEALKIALGDKRGICRFGFVLPMDECLARCALDISGR
                     PHLEYKAEFTYQRVGDLSTEMIEHFFRSLSYTMGVTLHLKTKGKNDHHRVESLFKAFG
                     RTLRQAIRVEGDTLPSSKGVL"
     gene            complement(14608..15678)
                     /gene="hisC"
                     /locus_tag="RHX21_002976"
     CDS             complement(14608..15678)
                     /gene="hisC"
                     /locus_tag="RHX21_002976"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HDV1988129.1"
                     /translation="MSTVTITDLARENVRNLTPYQSARRLGGNGDVWLNANEYPTAVE
                     FQLTQQTLNRYPECQPKAVIENYAQYAGVKPEQVLVSRGADEGIELLIRAFCEPGKDA
                     ILYCPPTYGMYSVSAETIGVECRTVPTLDNWQLDLQGISDKLDGVKVVYVCSPNNPTG
                     QLINPQDFRTLLELTRGKAIVVADEAYIEFCPQASLAGWLAEYPHLAILRTLSKAFAL
                     AGLRCGFTLANEEVINLLMKVIAPYPLSTPVADIAAQALSPQGIVAMRERVAQIIAER
                     EYLIAALKEIPCVEQVFDSETNYILARFKASSAVFKSLWDQGIILRDQNKQPSLSGCL
                     RITVGTREESQRVIDALRAEQV"
     gene            complement(15675..16979)
                     /gene="hisD"
                     /locus_tag="RHX21_002977"
     CDS             complement(15675..16979)
                     /gene="hisD"
                     /locus_tag="RHX21_002977"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HDV1988130.1"
                     /translation="MSFNTIIDWNSCTAEQQRQLLMRPAISASESITRTVNDILDNVK
                     ARGDEALREYSAKFDKTTVTALKVSAEEIAAASERLSDELKQAMAVAVKNIETFHTAQ
                     KLPPVDVETQPGVRCQQVTSPVASVGLYIPGGSAPLFSTVLMLATPARIAGCKKVVLC
                     SPPPIADEILYAAQLCGVQDVFNVGGAQAIAALAFGTESVPKVDKIFGPGNAFVTEAK
                     RQVSQRLDGAAIDMPAGPSEVLVIADSGATPDFVASDLLSQAEHGPDSQVILLTPDAD
                     MARRVAEAVERQLAELPRAETARQALSASRLIVTKDLAQCVEISNQYGPEHLIIQTRN
                     ARELVDGITSAGSVFLGDWSPESAGDYASGTNHVLPTYGYTATCSSLGLADFQKRMTV
                     QELSKEGFSALASTIETLASAERLTAHKNAVTLRVNALKEQA"
     gene            complement(16985..17884)
                     /gene="hisG"
                     /locus_tag="RHX21_002978"
     CDS             complement(16985..17884)
                     /gene="hisG"
                     /locus_tag="RHX21_002978"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HDV1988131.1"
                     /translation="MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAE
                     NMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFG
                     GCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPR
                     AGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGKMEESKQQLIDKLLTRIQ
                     GVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWE
                     TMEKLKALGASSILVLPIEKMME"
     misc_feature    complement(17931..18054)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00514"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="His leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00514"
     gene            complement(18030..18080)
                     /gene="hisL"
                     /locus_tag="RHX21_002979"
     CDS             complement(18030..18080)
                     /gene="hisL"
                     /locus_tag="RHX21_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="his operon leader peptide"
                     /protein_id="HDV1988132.1"
                     /translation="MTRVQFKHHHHHHHPD"
     gene            18363..18614
                     /gene="yefM"
                     /locus_tag="RHX21_002980"
     CDS             18363..18614
                     /gene="yefM"
                     /locus_tag="RHX21_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoeB-YefM toxin-antitoxin system antitoxin YefM"
                     /protein_id="HDV1988133.1"
                     /translation="MRTISYSEARQNLSATMMKAVEDHAPILITRQNGEACVLMSLEE
                     YNSLEETAYLLRSPANARRLMDSIDSLKSGKGTEKDIIE"
     gene            18611..18865
                     /gene="yoeB"
                     /locus_tag="RHX21_002981"
     CDS             18611..18865
                     /gene="yoeB"
                     /locus_tag="RHX21_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin YoeB"
                     /protein_id="HDV1988134.1"
                     /translation="MKLIWSEESWDDYLYWQETDKRIVKKINELIKDTRRTPFEGKGK
                     PEPLKHNLSGFWSRRITEEHRLVYAVTDDSLLIAACRYHY"
     gene            18948..19772
                     /locus_tag="RHX21_002982"
     CDS             18948..19772
                     /locus_tag="RHX21_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDV1988135.1"
                     /translation="MKKVAIVGLGWLGMPLAMSLSARGWQVTGSKTTQDGVEAARMSG
                     IDSYLLRMEPELVCDSDDLDALMDADALVITLPARRSGPGDEFYLQAVQELVDSALAH
                     RIPRIIFTSSTSVYGDAQGTVKETTPRNPVTNSGRVLEELEDWLHNLPGTSVDILRLA
                     GLVGPGRHPGRFFAGKTAPDGEHGVNLVHLEDVIGAITLLLQAPKGGHIYNICAPAHP
                     ARNVFYPQMARLLGLEPPQFRNSLDSGKGKIIDGSRICNELGFEYQYPDPLVMPLE"
     gene            19818..20747
                     /locus_tag="RHX21_002983"
     CDS             19818..20747
                     /locus_tag="RHX21_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416519.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV1988136.1"
                     /translation="MKPLLDVLMILDALEKEGSFAAASAKLYKTPSALSYTVHKLESD
                     LNIQLLDRSGHRAKFTRTGKMLLEKGREVLHTVRELEKQAIKLHEGWENELVIGVDDT
                     FPFSLLAPLIEAFYQHHSVTRLKFINGVLGGSWDALTQGRADIIVGAMHEPPSSSEFG
                     FSRLGDLEQVFAVAPHHPLALEEEPLNRRIIKRYRAIVVGDTAQAGASTASQLLDEQE
                     AITVFDFKTKLELQISGLGCGYLPRYLAQRFLDSGALIEKKVVAQTLFEPVWIGWNEQ
                     TAGLASGWWRDEILANSAIAGVYAKSDDGKSAI"
     gene            20962..21024
                     /gene="yoeI"
                     /locus_tag="RHX21_002984"
     CDS             20962..21024
                     /gene="yoeI"
                     /locus_tag="RHX21_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein YoeI"
                     /protein_id="HDV1988137.1"
                     /translation="MGQFFAYATVITVKENDHVA"
     gene            21014..22372
                     /gene="plaP"
                     /locus_tag="RHX21_002985"
     CDS             21014..22372
                     /gene="plaP"
                     /locus_tag="RHX21_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416518.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine/proton symporter PlaP"
                     /protein_id="HDV1988138.1"
                     /translation="MSHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVS
                     GLTDGHVPTAYAFALIAILFTALSYGKLVRRYPSAGSAYTYAQKSISPTVGFMVGWSS
                     LLDYLFAPMINILLAKIYFEALVPSIPSWMFVVALVAFMTAFNLRSLKSVANFNTVIV
                     VLQVVLIAVILGMVVYGVFEGEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFD
                     GISNLSEETKDAERVIPRAIFLTALIGGMIFIFATYFLQLYFPDISRFKDPDASQPEI
                     MLYVAGKAFQVGALIFSTITVLASGMAAHAGVARLMYVMGRDGVFPKSFFGYVHPKWR
                     TPAMNIILVGAIALLAINFDLVMATALINFGALVAFTFVNLSVISQFWIREKRNKTLK
                     DHFQYLFLPMCGALTVGALWVNLEESSMVLGLIWAAIGLIYLACVTKSFRNPVPQYED
                     VA"
BASE COUNT         5004 a         5870 c         6110 g         5439 t
ORIGIN      
        1 ccctggggcc gctgcgacgt ggtggtccag accccgcgat tcaacgtcaa ccgtatcacg
       61 gtgaaaccag gcggtgcctt ctcgatgcag atgcaccacc atcgcgccga gcattgggtt
      121 attctcgccg gcaccggtca ggtgactgtc aacggtaagc agttcctgtt gtccgagaac
      181 cagtccacct ttattccgat tggcgccgag cactgcctgg aaaaccctgg ctgtattccg
      241 ctggaagtgc tggagatcca gtcgggggcg taccttggcg aggacgacat tattcgtatt
      301 aaagaccagt atggtcgttg ctaattattt tcgggacaag acgcagaatg acacagttaa
      361 cttgttttaa agcttatgac atccgtggtg aactgggtga ggaactgaac gaggacatcg
      421 cctaccgtat cggtcgcgcc tacggcgaat ttctgaaacc cgggaagata gtggtggggg
      481 gcgatgtgcg cctcacaagc gagtcgctga agctggcgct ggcccgcggg ttaatggacg
      541 ccggtaccga cgtgctggac atcggcctga gcggtaccga agagatttac tttgccacct
      601 tccaccttgg ggtagatggt ggcatcgagg tgaccgcgag ccacaatcct atgaactaca
      661 acggcatgaa gctggtgcgc gagaatgcga agcccatcag cggcgacacc ggcctgcggg
      721 atatccagcg cctggcggag gaaaaccagt tcccgccagt ggacccggcg cgtcgcggga
      781 ccctgagcaa gatatcggta ctgaaggagt atgttgacca tctgatgagc tacgtggact
      841 tctcgaactt cacccgtcca ctgaagttgg tggtgaactc cggaaacggg gctgcggggc
      901 acgtgattga tgaggtggag aaacgcttcg cggcggccgg ggtgccggta acctttatca
      961 aggtgcatca ccagccggat ggccatttcc ctaacggtat cccgaatccg ctgctgccgg
     1021 agtgccgcca ggataccgcc gacgcggtgc gcgagcatca ggccgacatg gggattgcct
     1081 ttgacggcga cttcgatcgc tgcttcctgt tcgatgacga agcttcgttt atcgaggggt
     1141 attacattgt cggcctgctg gctgaggcgt tcctgcagaa gcagccggga gcgaaaatca
     1201 ttcacgaccc gcgcttgacg tggaacacgg tagacatcgt gacccgcaac ggcggccagc
     1261 cggtgatgtc gaagacgggg catgcgttca tcaaggagcg gatgcgtcag gaagacgcta
     1321 tctacggcgg ggagatgagt gcgcaccatt acttccgcga tttcgcctac tgcgatagcg
     1381 ggatgatccc gtggctgctg gtggcggagc tgctgtgtct gaagaacagc tcgctgaaat
     1441 cgctggtggc ggaccgccag agggcgttcc ctgcgtcggg agagatcaac cgcaagctaa
     1501 ggaatgcggc tgaggcgatc gcccgcatcc gggcgaagta tgagccggcg gctgcacaca
     1561 tcgacacaac ggacgggatc agtattgaat accctgaatg gcgctttaac ctgcgcacgt
     1621 ctaacaccga gccggtggtg cgtctgaacg ttgagtccag agctgatgtg gcgcttatga
     1681 atgaaaaaac gaccgagctg ctcaacctgt taaaagagga attgctttga gtccgatgtt
     1741 ttcagcgatc tatcgctacc gtggctttat tattgacagc gttaaacggg actttcagtc
     1801 ccgttaccaa accagcttct taggcgcggc atggctgatt ttacagccga tcgccatgat
     1861 ttccgtctat acattaattt tttctgaatt aatgcgtgcc cgcctggctg gcatggatgg
     1921 tccttttgca tacagcatct acttgtgttc tggggtgtta acttgggggc tgttcacgga
     1981 aacgctcaac agtctggtca acgtttttct gaccaacgcc aatattctta agaagctcag
     2041 ctttccgcgg atctgtttac cgatcatcgt cactgcttcg gcatttatta acttcctgat
     2101 catttttggt ctgttcgtgc tgtttctgat cgtcacgggc aatttccctg gcatgatttt
     2161 ctttgaaatc attccggtgc tgatcgtcca gatgctgttc accctcggcc tcgggatcat
     2221 tctcggggta ctgaacgttt ttgtccgcga tgtcgggcag ttcgttaata tactgcttca
     2281 gttttggttc tggtttacgc caattgtcta cgtatccaaa acgctgccgg aatgggtttc
     2341 tggtctgttg gcgtataacc cgatggcgac tattattggc tcataccaga acgtgatgct
     2401 ctatcaccag agccctaact ggctggctct gcttcctgtt gcggtgctgt ccgtcattct
     2461 gtttttattt gcctggcgtt tatttaaaaa acatgccgct gatattgtgg acgagattta
     2521 atcatgagta tcaaagttca gcacgtcggc aaggcgtata aatattatcc atctaaatgg
     2581 aaccgggtca ttgagaaact actgccgggc gataagccgc ggcacagcaa gaaatgggta
     2641 ttgaaagata tcaatttcag cattgaacct ggggaagcgg tcggcattgt tggggtgaac
     2701 ggcgcaggta aaagtacgtt actgaagctg ctgactggca ccactcagcc caccaaaggt
     2761 agcattgaaa tccaggggcg cgtcgccgcg ctgctggagc tgggcatggg cttccatcct
     2821 gactttaccg gccggcagaa cgtgtatatg tccgggctga tgatgggctt gagccgcgaa
     2881 gagatcgagt gtttaatgcc ggagatcgaa gcctttgcag atatcggcga ctacattgaa
     2941 gagccagtgc gcgtctattc cagcgggatg cagatgcgac tggcgtttgc cgtggccacg
     3001 gcttcccgcc cggatattct aatcgtcgat gaggcgctct cagtcggtga ctcccgtttt
     3061 caggcgaagt gctacgctcg aattgcggat tttaaaaagc agggcaccac gctgctgctg
     3121 gtctcccata gcgccggtga tatagtcaaa cactgcgacc gcgccatttt cctcaaaaat
     3181 ggtgacatct gcatggacgg caccgcccgc gacgtaacca accgttacct ggatgagctg
     3241 tttggcaaac cggataaaga cagcgcgaca aaaagcgcaa cggctatctc gtcagccagt
     3301 ggcgaaagcc agatgtctct cgatgagatt gaagatgtgt accacacgcg cccaggctac
     3361 cgtccggaag aatatcgctg ggggcagggt ggcgcgaaaa tcatcgatta tcatatccag
     3421 agcgccgggg ttgattttcc tccctcactg acgggcaatc agcagaccga ttttctgatg
     3481 aaggtcgtgt ttgaatacga ttttgattgc gtggtgccag gcatcctgat taagaccctc
     3541 gatggcttat tcctctacgg aaccaactct ttcctcgcct ctgaagggcg ggaaaatatt
     3601 tcggtttccc gcggcgatgt tcgggtcttt aaatttagcc ttccggttga tttaaatagt
     3661 ggcgattacc tgctgtcatt tggtatctct gccggcaacc cgcagacgga tatgacgccg
     3721 ctggacagac gttacgactc cattatttta catgtgacca agagcatgga tttctggggt
     3781 gtcatcgatc ttaagtcgtc ctttactagc taccaatgac gttgagaaaa acgattccat
     3841 gactaaagac ttaaacacgc tggttagcga attacctgag atttatcaaa ctatttttgg
     3901 ccatcccgaa tgggatggcg acgccgctcg tgattgtaat caacgcctcg atttgattac
     3961 cgaacagtac gataacttat cccgtgcgct ggggcgcccg cttaacgttc tcgatctggg
     4021 ctgcgcgcag ggctttttta gcctgagtct ggcaagcaaa ggcgcgacta tcgttggtat
     4081 cgatttccag caggaaaata ttaacgtgtg ccgcgcgctg gccgaagaga accccgattt
     4141 tgccgccgag ttccgggtag gcagaattga agaggtgatc gccgcgctgg aagagggcga
     4201 gtttgatctg gccattggct taagcgtgtt tcaccatatt gttcaccttc atggtatcga
     4261 tgaagttaaa cgtctgctct cgcgcttggc cgatgtcacc caggcggtga tccttgagct
     4321 ggcggtgaaa gaagaaccgc tttactgggg cgtttctcag ccggacgacc cgcgcgaact
     4381 gattgagcag tgcgcgtttt atcgcctgat cggtgagttt gacacccatt tatcccccgt
     4441 accgcgcccg atgtacctgg tcagcaacca ccgggtgctg atcaacgatt ttaatcagcc
     4501 gttccagcac tggcagaatc agccctatgc cggggccggc ctggcgcata agcgcagccg
     4561 tcgctacttc tttggcgaag attatgtatg caagtttttc tattacgaca tgccccacgg
     4621 catcctgacg gcggaagaga gccagcgtaa taaaaacgaa ctgcataatg aaatgtgttt
     4681 tctggcacaa ccccctacgg gctttgacac gccggcatta ctagcccacg gcgaaaatgc
     4741 ccagtctggt tggctggtaa tggaaaaact cccgggtagc ttgctgagcg atatgctggt
     4801 ggccggggaa gagatcgatc gtgaaaaaat cattggcacc ttgctccgtt ccttagcggt
     4861 gctggagaag caagggttat ggcatgacga tgtgcgcccg tggaacgtga tggtcgatgc
     4921 acggcagcat gcccgcttaa tcgactttgg ttctatcgtc accacgccac aggactgcag
     4981 ctggccggca aaccttgtcc agtcgttctt cgtgtttgtg aatgagctgt ttgccgaaaa
     5041 caaaagctgg aacggtttct ggcgctcggc gcctgttcat ccgtttaatc tgcctcagcc
     5101 gtggtctaac tggctgtatg cggtctggca ggagccggtt gaacgctgga actttgccct
     5161 gctgttggcg ctgttcgaga agaaagcgaa gctgccgtca gctgaacagc agcgcggggc
     5221 gacggaacag tggatcatcg ctcaggagac ggtgctgctg gagctccagt cccgggtgct
     5281 aaatgaaagc gccggctcag aagcgttgcg cggccaaatc cataccctgg agcagcagat
     5341 ggctcagctg cagtccgctc aggatgcgtt cgtcgagaaa gctcaacagc cagtggaagt
     5401 cagccatgaa ctcacctggc ttggtgagaa tatggagcaa ctggcggcgc tgttgcagac
     5461 ggcgcaagcg cacgcccagg ctgacgttca gcccgagttg ccccctgaaa ccgctgagct
     5521 actgcagcga ctggaagccg ctaaccggga gatccaccat ttaagcaacg aaaaccaaca
     5581 gcttcgccag gaaattgaaa aaatccatcg cagccgttcc tggagaatga ccaagggtta
     5641 tcgttatctg ggcctgcaga tccatttgct gaggcagtat ggtttcgtgc agcggtgtaa
     5701 acattttatt aagcgcgtcc tgcggtttgt tttctcattt atgagaaaac atccgcaggt
     5761 aaaacatacc gcggtaaatg gtttacataa gctggggctt tatcagccgg cctatcgttt
     5821 gtatcgtcga atgaatccac tgccgcacag ccagtatcag gctgatgcgc agattttatc
     5881 gcagactgaa ctgcaagtga tgcatccgga acttttacct cccgtggttt atgaaattta
     5941 tctcaaacta acgaaaaata aataaggaga ttaacttgca tattttgatt gatgtccagg
     6001 gttaccagtc ggaaagtaaa gtccgcggta ttggtcgcag taccctggcc atgagccgcg
     6061 ccattattga aaatgccggt gagcatcgcg tcagtatttt gatcaatggt atgtatccca
     6121 ttgataatat taatgatgtt aaaatggcct atcgggacct gctgacggat gaagatatgt
     6181 tcatcttctc agccgtcgcg ccaacagcct atcgtcatat tgaaaaccat ggccgcagta
     6241 aagcggccca ggcggcccgc gatatcgcta tcgccaatat cgcgcctgat atcgtctatg
     6301 ttattagctt cttcgagggg catagcgata gttataccgt gtctattccg gcggataatg
     6361 tgccgtggaa aacggtgtgc gtatgccacg atctgatccc actgttaaat aaagagcgtt
     6421 atctcggcga tccgaatttc cgtgagtttt atatgaataa gctggcggaa tttgagcggg
     6481 cagacgcgat cttcgccatt tcgcagtcgg cagctcagga agtgatcgaa tataccgaca
     6541 tcgccagcga tcgggtactg aacatctcct cggcggtggg cgaagagttt gcggtgatcg
     6601 attattccgc tgagcgtatt cagtctttaa aagacaaata cagcctgccg gatgagttta
     6661 tcttgtcgct ggcgatgatc gagccgcgga aaaatattga agcgcttatt cacgcctaca
     6721 gcttgctgcc tgccgagctg cagcagcgct atccgatggt gctggcgtat aaagtgcagc
     6781 cagaacaact ggagcggatc ctgcgtctgg cggaaagcta tggtttgtca cgcagccagc
     6841 ttatctttac tgggttcctg accgacgacg atctgattgc cctgtacaac ctgtgcaaac
     6901 tgtttgtgtt cccgtcgctg catgaaggtt tcggcctgcc gccgctggaa gcgatgcgct
     6961 gcggggcggc gaccttaggt tcaaacatta ccagcctgcc ggaagtcatt ggctgggaag
     7021 atgccatgtt caatccgcat gatgtgcagg acattcgccg ggtcatggag aaggcgctga
     7081 ccgatgaggc gttttatcgt gagctgaagg cgcatgctct cgcgcagtcg gccaaattct
     7141 cgtgggccaa taccgcccat ctggcgatcg agggtttcac tcgtctgctg cagtcgtccc
     7201 aagagacgga tgccgggcag gcggaaagcg tgaccgcctc ccgccttcag atgatgcaga
     7261 aaatcgatgc gctgagcgaa gtcgaccgtc taggtctggc gtgggcggtt gcgcgcaata
     7321 gctttaagcg ccatacccgc aagctgctgg tggacatttc ggttctggcg cagcatgacg
     7381 cgaagaccgg gatccagcgc gtctcgcgca gtatcctcag cgaattactg aaatctggcg
     7441 tgccgggtta cgaggtttcc gccgtctact acacccctgg cgagtgttat cgctacgcca
     7501 accaatatct gtccagtcat ttcccgggcg aatttggtgc tgacgaaccg gtgctgttca
     7561 gcaaagacga tgtgcttatt gccaccgatc tgaccgcgca tctcttcccg gagctggtga
     7621 cgcaaattga cagcatgcgc gccgccgggg cgttcgcctg cttcgtggtg catgatattc
     7681 tgccattacg ccgtccggag tggagtatcg aaggcattca gcgtgatttc ccgatctggc
     7741 tgtcctgcct cgcagagcac gccgaccggc tgatctgcgt ctctgccagc gtcgccgagg
     7801 atgtgaaagc gtggattgcg gaaaatcgcc attgggtgaa accgaacccg ctgcagaccg
     7861 tcagcaactt ccatctggga gccgacctcg atgccagcgt accgtccact ggcatgccgg
     7921 ataatgcaca ggcgctgtta gcagcgatgg ctgcagctcc gtcatttatc atggtgggta
     7981 ccatggagcc gcgcaaaggc cacgcccaga cgctggccgc cttcgaggaa ctgtggcgcg
     8041 agggcaaaga ctacaacttg tttatcgtcg gcaaacaggg ctggaacgtt gacagcttgt
     8101 gcgaaaaatt acgccatcat ccccagctga acaaaaagct cttctggctg cagaatatca
     8161 gcgacgagtt tttggccgag ctatacgctc gttcacgcgc gctgatcttt gcctcgcagg
     8221 gagaaggctt tggcctgccg ttgattgaag cggcgcagaa aaagctgccg gtgattattc
     8281 gcgacattcc ggtgtttaaa gagattgctc aggaacatgc ctggtatttc tccggtgaag
     8341 cgccgtccga tatcgcgaag gcggtagaag agtggttagc cctgtacgag caaaacgcgc
     8401 atcctcgttc cgaaaatatc aactggttaa cctggaaaca gagcgcggaa tttctcctga
     8461 aaaacctgcc gattatcgcg ccagccgcga agcaataatc gctatcaaca gggctactgc
     8521 ggtggccctt gtgatgagtt cgttatgaaa attatttttg ctactgagcc aattaaatac
     8581 ccattaacgg gcatcggtcg gtattccctg gagctggtta agcggctggc ggttgcccgt
     8641 gaaatcgaag agctgaagct gtttcacggc gcgtcgttta tcgaccagat cccccaggtg
     8701 gagaataaaa gcgatagcaa agccagcaat catggtcgtc tgtcggcgtt tctgcgccgc
     8761 cagccgctgc tgattgaggc gtatcgcctg ctgcatccgc ggcgccaggc gtgggcattg
     8821 cgcgattaca aagactacat ttaccatggt cccaatttct atctgccgca tcgcctggaa
     8881 cgcgccgtga ccacgtttca tgacatctcc atttttacct gcccggaata tcatccaaaa
     8941 gatcgggttc gctatatgga gaagtccctg cacgagagcc tggattcggc gaagctgatc
     9001 ctgactgtct ccgacttctc gcgcaatgaa atcatccgcc tgttcaacta tccggcggat
     9061 cggatcgtca ccaccaagct ggcctgcagc agcgactata ttccgcgcag cccggcggag
     9121 tgcctgccgg tcctgcagaa atatcagctg gcgtggcagg ggtatgcgtt atatatcggc
     9181 accatggagc cgcgtaaaaa tatccgcggt ctgctgcagg cctatcagct gctgccgatg
     9241 gagacccgca tgcgctaccc gctgatcctc agcggttatc gcggatggga agacgatgtg
     9301 ctgtggcagt tagtcgagcg cggtacgcgt gaagggtgga tccgttacct gggctatgtc
     9361 ccggatgaag acctgcctta tctgtacgcg gcggccagaa cctttgttta tccctccttc
     9421 tatgagggat tcggtttacc tattcttgaa gcgatgtctt gcggtgtgcc ggtagtatgt
     9481 tccaatgtca cttctttgcc tgaggtggtt ggcgatgccg gcctcgttgc cgatcctaat
     9541 gatgtagacg cgattagcgc acatattttg cagagcctgc aggatgatag ctggcgggaa
     9601 atcgccaccg cgcgcggtct tgcccaggcg aaacagtttt cgtgggagaa ctgtacgacc
     9661 cagaccatta acgcctataa attactctaa gggtgtcagt tgagagttct acacgtctat
     9721 aagacctact atcccgatac ctacggcggt attgagcagg tcatttatca gctaagtcag
     9781 ggctgcgccc gccggggaat cgcagccgat gtttttactt ttagcccgga caaagagaca
     9841 ggtcctgtcg cctacgaaga ccatcgggtc atttataata agcagctttt tgaaattgcc
     9901 tccacgccgt tttcgttgaa agcgttaaag cgttttaagc agattaaaga tgattacgac
     9961 atcatcaact accattttcc gtttcctttc atggatatgt tgcatctctc ggcgcggcct
    10021 gacgcaagaa cggtggtgac ctatcactcg gatattgtga aacaaaaacg gttaatgaag
    10081 ttgtaccagc cgctgcagga gcgattcctc gccagcgtag actgcatcgt cgcctcgtcg
    10141 cccaactacg tggcctccag ccagaccctg aaaaaatatc aggataaaac cgtggtgatc
    10201 ccgtttggtc tggagcagca tgacgtgcag cacgatccgc agcgggtggc gcactggcgg
    10261 gaaaccgtcg gcgataactt cttcctcttc gtcggcgctt tccgctacta caaagggctg
    10321 cacattctgc tggatgccgc cgagcgtagc cggctgccgg tggtgatcgt cgggggcggg
    10381 ccgctggagg cggaagtgcg gcgtgaggcg cagcaacgcg ggctgagcaa tgtggtgttt
    10441 accggcatgc tcaacgacga agataagtac attctcttcc agctctgccg gggcgtggta
    10501 ttcccctcgc atctgcgctc tgaggcgttt ggcattacgt tattggaagg cgcacgcttt
    10561 gcaaggccgc tgatctcttg cgagatcggt acaggtacct ctttcattaa ccaggacaaa
    10621 gtgagtggtt gcgtgattcc gccgaatgat agccaggcgc tggtggaggc gatgaatgag
    10681 ctctggaata acgaggaaac ctccaaccgc tatggcgaaa actcgcgtcg tcgttttgaa
    10741 gagatgttta ctgccgacca tatgattgac gcctatgtca atctctacac tacattgctg
    10801 gaaagcaaat cctgagagct gctacccccg ccgttgctgc gggggccaac gcgttaatgc
    10861 cgattcttca gattatcaat cacttctccg agatccagcc cctgatcctg caacagcacc
    10921 agcaggtgat acatcaaatc agatgcctcg ttggtcagct caaagcggtc atttaccgtc
    10981 gcggccagtg cggtttccac cccttcttcg cccactttct gcgcaatgcg tttggtgccg
    11041 ctggcataca gtttggctgt gtaagaggtt tccgggtcgg cagatttgcg ttcggcgagc
    11101 agttgttcca gttgatacag gaacagccac tggtgagcgg tgtcgccgaa gcagctgctg
    11161 gtgcctttgt ggcaggttgg cccgatggga ttcgccagca ccagtaacgt gtcgttgtcg
    11221 cagtccgggg caatactcac cacattgaga aaattgccag acgtttcgcc tttggtccac
    11281 agccgttgtt tagttcgcga gaagaaggtg actttgccgc tttcgatagt tttgtccaga
    11341 gcttccgggt tcatatagcc cagcattaac acttcgccag ataccgcgtg ttgtacaatc
    11401 accggcatca gtccgtcggt tttttcccag tccagttcgt gacgttgttg ttctgttaac
    11461 atatcctgat ctccacgccc tgtgttgcca ggtacgcttt taattcacta atattgatta
    11521 tttgtttgtg gaatacagaa gctgccagcg caccgtcaac gtcggcatcg cggaaggctt
    11581 cgaggaagtg ttccatggtg cccgcgccac cggaggcaat cagcgggacg tggcaaactt
    11641 cacgcacttt tttcagttgt tctaggtcgt aaccgttacg cacgccgtcc tgattcatca
    11701 tgttgaggac gatttctccg gcaccgcgtt tttgcacttc ctctacccag tcgagcgttt
    11761 cccactgagt gacgcgggtg cggctttcat cgccggtata ttgattcaca tgatatttac
    11821 cggtttcggc gtcgtaccag gtatcaatac cgaccacaat acactgcact ccaaagcgat
    11881 cggccaggcg agtgattaac gtcgggtccg ccagcgcagg ggagttaatg gaaattttat
    11941 ccgcgccaaa agaaagaatt ttcgcggcgt catccagcga cttaatccca cccgccacgc
    12001 agaacgggat gtcgatcact tccgccacgc gggataccca gcttttatct accacgcgtc
    12061 catcactgga ggctgtgata tcgtagaaca ccagttcgtc agcgccttct tcggcgtagc
    12121 gttttgccag cggtacaata tcgccaatga tttcatggtt gcgaaactgt acgcctttca
    12181 ccacctgacc atcacgaacg tcgagacatg gaattatgcg ttttgccagc atgcgatggc
    12241 ctccttcacg gtgaatttac cttccagtaa tgcccgacca actattacgc cgcgcacgcc
    12301 agtaccacgt agagcagcaa catcatcaat gtcgccaata ccgccggagg actgaaatgc
    12361 cacctgcgga tatctggcgc aaacttcttc atataaagag acgttagaac ctgccagcgt
    12421 gccgtctcgc gagatatcgg tacacagcac atgtttcagg ccgacgggca gataggtttc
    12481 caccagttgt tccagtgaaa cgcccgagtt ctcttgccag ccgctgactg ccacctgctt
    12541 gttgccttgc tcgtcaatac ggacatccag cgccagcact aaggcatcgg caccaaaacg
    12601 ttcaaaccag accttcacca tttctggtga tttcaccgcg gtggagccga ccaccacgcg
    12661 cgcaacgccc gcttccagta acgccgccac gtcttcttcg ctacgcacgc cgccgccaac
    12721 ctgcaccgga acgttaacgc ccgccaccag ggttttaatc agcgggattt gacgtctagc
    12781 cggatctttt gctccggtca gatccaccag atgcaacact tcggcaccct gcgcggcgta
    12841 atcctgtaag cgcggcagcg ggtcgttacc gtaatcgcgt tgtttgccgt aatcgccctg
    12901 atggagacgc accacggtgc cgtcgattaa atctaatgcc ggaataatca tcacatctcc
    12961 aggaagtttt tcagcaactt agcgccagcg gcaccagaac gctccgggtg gaactgcacg
    13021 ccgtagaagt tatctttttg taccgccgcg gtgaacggtt cgccgtaatt acactgggcg
    13081 atggtccacg gattgaccgg cattgcgtag ctgtgaacaa agtaaaagta cgcgccgtct
    13141 tcaatcccct gaaacaggcg gttgcctgcc tgcgggtaaa cgcggttcca gcccatatgt
    13201 ggcagcggca gaccaaagtc ggtcattttc ggcacgtctt cgtcgatgat gcccagcaaa
    13261 tcgacgccgt tgctctcttc gctgcgccgc cccagcagtt gcatccctaa gcagatgccc
    13321 agcaccggtt gggtacaggc tttgatgaga tcaaacaact cgcgctcacg cacctggtcc
    13381 atcgccgctt gcgcggtgcc aacgccgggt aaaaacagtt tatcggccag caacacgacg
    13441 tccgggtcac ggctaacttt gggttcataa ccgtgacgcg caatggcaga cttcaccgag
    13501 ttcaaattgg cgcagccggt atcaaggatc accacgttca ttacagcact cctttcgacg
    13561 agggtagggt gtcgccttcc acgcggatgg cctggcgcag ggtgcgacca aaagctttga
    13621 acaggctctc tactcggtgg tgatcgtttt tacctttggt tttcaggtgc agggtcacgc
    13681 ccatagtgta tgagagcgaa cggaagaagt gctcgatcat ctcggtgctg agatcgccca
    13741 cgcgctggta ggtaaattca gctttatatt ccaggtgcgg gcgaccagag atatccagcg
    13801 cgcagcgggc aaggcattcg tccatcggca gtacaaaacc aaagcggcaa ataccgcgtt
    13861 tgtcgccaag ggcgattttt aacgcttcgc ccagcgccag gccggtatct tcgacggtgt
    13921 ggtgatcgtc gatatagagg tcgcctttga cgttgatttc catacggaaa ccgccgtggg
    13981 tggcgatctg atccagcata tgatcaaaga agccaacgcc ggtgttaatc ttgctgccac
    14041 cttcgcgatc cagccacacc tggacgtcaa tttgcgtctc tttggtgttg cgcactacat
    14101 gggcgtaacg gtctcgttta gtgagctgct cgccaatcat tggccagttc agggtttcgc
    14161 ggtcgtagcg taaaccatta atgcccatgt tttccgccag ctgaatatcg gtcgcgcgat
    14221 cgccaatcac ataactattg gcacgatcca tcgcttgctc agccagataa cgctccacca
    14281 gttttacttt cggcttacgg cagtcgcact catcggcggg caggtgcgga caaatcagca
    14341 cttcatcaaa ctgcacgcct tgcgaggtga agatctgcat catcaggttg tgcgggccat
    14401 cgaaatccac ctgcgggaaa ctttgtgttc ccagaccatc ctgattggtg atcatcacca
    14461 gcttgtagcc cgctttttgc agcttcagca gctgcgggat cacgcccggt tcaaaggcga
    14521 gtttgtcaaa acggtccacc tgaaaatcac tcggcggttc gctaatcagg gttccatcgc
    14581 gatcgataaa aagatacttc tgactcatca aacttgctcc gcacgtaagg cgtcaatgac
    14641 gcgctggctt tcttcacggg ttccgacggt aattcgcagg cagccgctta aagagggttg
    14701 tttattctga tcacgtaaga taatgccctg atcccacaaa gatttaaaca ctgcgctgga
    14761 ggctttaaag cgcgccagaa tgtagttggt ttcagagtca aaaacctgct ccacgcaggg
    14821 gatctctttc aatgcggcaa tcagatattc gcgttctgca ataatttgcg ccacccgctc
    14881 acgcatggcg acgatcccct gcgggcttaa cgcctgggcc gcaatgtcgg caaccggcgt
    14941 cgagagcggg tagggggcga tcactttcat taacaggttg atgacctctt cgtttgccag
    15001 cgtaaatccg caacgaagcc ccgccagagc aaaagctttc gacagtgtgc gcaaaatagc
    15061 caggtgcgga tattccgcca gccagccagc cagcgatgcc tgtggacaaa actctatata
    15121 ggcttcatcg gcaaccacaa tcgccttacc gcgcgttaac tccagcaggg tgcgaaaatc
    15181 ctgcgggttg atcagttgcc cggtcgggtt gttggggctg caaacataga ccacttttac
    15241 gccgtccagc ttgtcggaaa tgccctgtaa gtccagttgc cagttgtcca gcgtcggcac
    15301 tgtgcggcac tcgacgccaa tcgtttcggc gctgacgctg tacatgccgt acgttggcgg
    15361 gcagtagagg atggcgtctt tacccggttc gcaaaaagcg cgaatcagca gttcaatacc
    15421 ttcgtccgcg ccacggctga ccagcacctg ctccggtttt acgcctgcat attgcgcgta
    15481 attttcaatc accgctttcg gctggcattc cgggtagcgg ttgagcgttt gctgagtaag
    15541 ctgaaactcc acggcagtgg ggtattcgtt ggcgttcagc cagacatcgc cgttaccgcc
    15601 cagacgacgc gctgactgat acggcgtcag gttgcggacg ttttcacgcg ctaaatcggt
    15661 aatagtcacg gtgctcatgc ttgctcctta agggcgttaa cacgcaaagt aacggcattt
    15721 ttatgggcgg tcaggcgctc ggcggaggcc agtgtttcaa tggtcgaagc cagcgcggaa
    15781 aagccttctt tcgagagttc ctgcacggtc atgcgcttct ggaaatctgc cagcccgagg
    15841 ctggaacagg tggcggtgta accgtaagtc ggtagaacat ggttagtgcc ggaggcatag
    15901 tcgcctgccg attccggtga ccagtcacca agaaataccg aaccggcgct ggtgatgcca
    15961 tcgaccagtt cgcgggcgtt gcgggtctga atgatcaggt gctccgggcc gtactggttg
    16021 gaaatctcta cgcactgcgc taaatcttta gtcacgatca ggcggctggc gctcagtgcc
    16081 tgacgtgcgg tttcggcacg cggcagttct gccagctggc gttcgacagc ttcggcaacg
    16141 cgacgcgcca tatcagcatc gggcgtcagt aaaatcacct gagagtccgg gccgtgttca
    16201 gcctgagaaa gcaaatcaga agccacgaaa tctggcgtag cgccgctgtc ggcaatcacc
    16261 agcacttccg acgggcctgc gggcatatcg atcgccgcac cgtccagacg ctggcttacc
    16321 tggcgttttg cctcggtgac aaaggcgttg cctggcccga agattttgtc cacttttggc
    16381 acagattcag taccaaacgc cagtgcggca atggcctgtg cgccgccgac gttaaacacg
    16441 tcctgtacac cgcacagctg cgccgcataa aggatctcat cggcaatcgg cggcggtgag
    16501 cacagcacca cttttttaca gcccgcaata cgcgccggag ttgccagcat taataccgtt
    16561 gagaagagcg gggcggagcc gccaggaata tacaaaccta ccgaagccac cgggctcgtg
    16621 acttgctgac aacgtacgcc tggctgagtt tctacatcta ccggcggcag tttttgcgca
    16681 gtgtggaagg tttcaatatt ctttactgcc accgccatcg cctgttttag ctcgtcgctc
    16741 aggcgttcgc tggcggcggc aatttcctct gcagacacct tcagcgcggt aaccgtggtt
    16801 ttatcaaact tcgcgctgta ttcccgcagg gcctcatcgc cgcgtgcttt cacgttatcg
    16861 agaatatcgt taacagtgcg ggtaatgctt tcagaagcgg agatcgccgg gcgcattaat
    16921 agctggcgtt gttgctccgc agtacagcta ttccagtcaa tgattgtgtt aaagctcatg
    16981 gcgatcactc catcatcttc tcaatcggca ggaccaggat tgaactggca cccagcgctt
    17041 tcagtttttc catcgtttcc cagaacaggg tttcgctact gaccatgtgc atcgctacgc
    17101 gttgttggtc acccgccagc ggcagaatgg ttgggcgttc ggcacctggc agcagggcga
    17161 tgacttcatc cagacgttcg gtcggtgcgt gcatcatgat gtattttgat tcgcgcgcct
    17221 ggatcacacc ctgaatacgg gtcagcagtt tgtcgatcag ttgctgtttg gattcttcca
    17281 ttttgccatc gcgctggatc aggcaggctt tcgagcggta gataacttcg acttcgcgca
    17341 ggccgttagc ttccagcgtg gcaccggtgg aaaccagatc gcaaatcgca tccgccagtc
    17401 cggcacgcgg ggcgacttca acagaaccgt tcagtaagca ggatttaaaa gagatgcctt
    17461 tctggtcgag ataacgcttg agcaggtgag gataagaggt ggcgatacgt ttaccgttta
    17521 aggagagcgg gccgtcccag gcttcatcaa ctggcgttgc cagcgaaaga cggcagccgc
    17581 cgaaatccag acgacgcagg gtaaagtagc gtggatcttc accctgggcg cggcggttaa
    17641 gcagctcttc ttccagcacg ttttcgccga taatcccaag gtcaaccacg ccatccatta
    17701 ccagaccggg aatgtcgtcg tcacgcacgc gcagaatatc aatcggcatg ttttctgcca
    17761 tcgcgatcag gcgctgggtg tgaagattga ttttaatgcc acagcgcgcc agcaattcgc
    17821 gtgagtcatc acttaaacgg ccggatttct gcatagctat gcgtaaacga gtgttgtctg
    17881 tcattttctt attcctcttt aaacctgtct gaaccgttat caaccgcgca ataaaaaagc
    17941 ccccggaagg tgatcttccg ggggctttct catgcgttca tgcaccactg gaagatctga
    18001 atgtcttcca gcacacatcg cctgaaagac tagtcaggat gatggtgatg atggtggtgt
    18061 ttaaattgaa cgcgtgtcat aaaagtctct gtgaatgttt attcaactga tgtcttttaa
    18121 cctaaaccac tttcacgtta gaaagcaagg gcttttttat atattttatg gcgatggatt
    18181 tgtttaatga atgagcgggg aaaggagggg gctaagagga ctgtcctcta acttgacagc
    18241 accaaaaaga gcaaagtctg atttttcgtc tcgctggcaa tgtcttgatc tacaaactaa
    18301 ttaataaata gtgaattaac acccatcatt gtacaatgaa ctgtacaaaa gaggagattt
    18361 acatgcgtac aattagctac agcgaagcgc gtcagaattt gtcggcaaca atgatgaaag
    18421 ccgttgaaga tcatgccccg atcctcatta ctcgtcagaa tggagaggct tgtgttctga
    18481 tgtcactcga agaatacaac tcgctggaag agacggctta tctactgcgt tcccccgcta
    18541 acgcccggag attgatggac tcaatcgata gcctgaaatc aggcaaagga acggaaaagg
    18601 acattattga gtgaaactaa tctggtctga ggaatcatgg gatgattatc tgtactggca
    18661 ggaaacagat aagcgaattg ttaaaaagat caatgaactt atcaaagata cccgcagaac
    18721 accatttgaa ggtaagggga aaccagaacc cctgaaacat aatttgtcag gtttctggtc
    18781 ccgacgcatt acagaggagc accgtctggt atacgcggtt actgatgatt cactgctcat
    18841 tgcagcatgt cgttatcatt attgaacaga ttcattcata gaatgaattg tcagttttga
    18901 tacgctagcg tagccttata gatctaaggt gtatcaggag ataacggatg aaaaaggtcg
    18961 caattgtcgg gttagggtgg ttaggcatgc cgctggcgat gtcactttca gcgcgaggct
    19021 ggcaagtcac cgggagtaaa accacacaag atggtgtcga agcggcccga atgagtggca
    19081 ttgatagcta tctgcttcgc atggagcctg agttagtttg cgattctgac gatctggatg
    19141 ccctgatgga tgccgatgcg ctggtcatta cgcttccggc acgtcgtagc ggccccggcg
    19201 atgagttcta tttacaagcg gtacaagagt tagtggatag cgcgctggcc catcgtattc
    19261 cccgcattat ttttaccagc tcgacatctg tctatggcga cgcgcaaggc acggtgaaag
    19321 aaaccacccc gcgtaatccg gtgaccaaca gtggacgagt attagaagaa ctcgaagact
    19381 ggctgcacaa tttacccggt acttcggtcg atattctgcg tcttgcgggc ctggtcggac
    19441 cgggacgtca tcccggacgc ttctttgccg gaaaaaccgc ccctgatggt gaacatggtg
    19501 ttaatttagt ccatttagaa gatgttattg gcgctatcac tctgttgtta caggcaccta
    19561 aaggcggaca catctataat atatgtgcgc cagctcaccc tgcgcgtaat gttttctatc
    19621 cgcagatggc ccgtttattg gggctggaac ctccgcagtt cagaaatagt ctggacagcg
    19681 gcaaaggtaa gattattgat ggcagtcgga tttgtaatga actgggattt gaataccagt
    19741 atcccgatcc gctggtaatg ccgctggagt aaacgatcac gccagcagga cgccgcatat
    19801 actgcaaggg ggcgtgtatg aaaccactgc tggatgtgtt gatgatcctc gatgccttag
    19861 aaaaagaagg cagttttgcg gcggcgtcgg ccaaactcta caagacgccg tccgctctga
    19921 gttacaccgt tcacaagctg gaaagcgacc ttaatattca attgcttgat cgcagcggac
    19981 accgcgctaa attcacccgc accggaaaaa tgttattaga gaaagggcgg gaagttctgc
    20041 ataccgtgcg agaactggaa aagcaggcga tcaaactgca tgaaggctgg gaaaacgagc
    20101 tggtgattgg cgtggacgac accttccctt tttctctgct tgcgccactc attgaggctt
    20161 tttatcaaca tcatagcgtg acgcgcctga agtttatcaa tggtgtactc ggtggttcat
    20221 gggatgccct gactcagggg cgagcggata ttattgttgg cgcgatgcat gagccaccat
    20281 cttccagtga gtttggtttc tctcggttgg gcgatctgga acaagtcttt gcggtcgcgc
    20341 ctcatcatcc gttagccctg gaagaagaac cgttaaaccg tcgtatcatt aaacgatatc
    20401 gggcgattgt ggtgggggac actgcacagg ccggcgcttc tacggcctca caacttctcg
    20461 acgaacaaga agctattacc gttttcgatt ttaaaaccaa gctggagctg caaattagcg
    20521 gcctcggctg cggctattta ccccgttatc tggcgcaacg ttttctcgat agtggtgcgt
    20581 taatcgagaa gaaagtggtc gcccaaaccc tctttgaacc cgtctggatt ggctggaatg
    20641 aacagaccgc ggggcttgcc agtggttggt ggcgggacga aattttagca aatagtgcga
    20701 tcgccggtgt ttatgcaaaa tctgatgacg gaaaatcagc catttaaaga aaaattatta
    20761 tgacaagcct ctcattctct tgtcatttcc cccccattta ggcacaatgc gccgctgtca
    20821 aaaaatgact aaaaaccgac gtttcattag cgtcggttat tttttgcttc aaaccaatca
    20881 ttcataccaa gaggccgggc ttcgtaccgg atagatattt actaaaaatc gacagttgtt
    20941 gtcgctgagg aatccaaaaa aatggggcaa ttttttgctt acgcgacggt tatcaccgta
    21001 aaggagaatg accatgtcgc ataacgttac tccaaacacc tctcgcgtgg aattgcgtaa
    21061 aacgcttacg ttagttccgg ttgtaatgat gggtcttgcc tatatgcagc cgatgacgct
    21121 gtttgataca tttggtatcg tttcaggcct cacggatggt catgtgccga cagcctatgc
    21181 gttcgcattg attgcgatcc tgtttacggc tctgagctac gggaagctgg ttcgccgcta
    21241 tccttctgct ggctctgcat acacttacgc ccagaaatcc attagcccga ctgtcggctt
    21301 tatggtgggt tggtcttctc tgctcgacta tctgttcgcg ccgatgatca acattctgct
    21361 ggcgaaaatc tattttgaag ctctggtgcc ttccatccca tcgtggatgt ttgtggtggc
    21421 gctggtggcc tttatgaccg cctttaacct gcgtagtctg aaatccgtag cgaacttcaa
    21481 cactgtaatc gtcgtgttgc aggtagtgct gatcgcggtg attctgggca tggttgttta
    21541 tggcgtattt gaaggtgaag gcgcgggtac gctggcgagc actcgtccgt tctggtctgg
    21601 cgatgcgcat gttatcccga tgattaccgg ggcgacaatc ctgtgcttct cctttaccgg
    21661 ctttgacggc atcagcaacc tgtcggaaga aaccaaagat gcagagcgcg tgatcccgcg
    21721 tgcgattttc ctgaccgcgc tgattggcgg catgatcttc atctttgcaa cttacttcct
    21781 gcagctgtac ttcccggata tctctcgctt taaagatccg gatgcgtcac agcctgaaat
    21841 catgctgtac gttgcgggta aagcgttcca ggttggcgcg ctgatcttct ccaccattac
    21901 cgtactggcg tccggtatgg cggcgcatgc aggcgtagcg cgtctgatgt acgtaatggg
    21961 gcgtgacggt gtgttcccga aaagcttctt cggttatgta cacccgaaat ggcgtactcc
    22021 ggcaatgaac atcatcctgg ttggcgcgat tgccttgctg gcaatcaact tcgacctggt
    22081 aatggctacg gcgctgatta actttggtgc gctggtggcg ttcaccttcg ttaacctgtc
    22141 ggttatttcg cagttctgga tccgtgagaa gcgtaacaag acgctgaaag atcacttcca
    22201 gtatctgttc ctgccgatgt gtggtgcgct gaccgttggt gcgctgtggg ttaacctgga
    22261 agaaagctca atggttctgg gtctgatctg ggctgctatc ggtctgattt acctggcttg
    22321 cgtaaccaag agtttccgta atccggttcc gcagtacgaa gacgtagcat aatcatcttt
    22381 tctaataata aaccggagtc gaatgaacat ttggctccgg ttt
//
LOCUS       DAPGUL010000073        22157 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.074, whole genome shotgun sequence.
ACCESSION   DAPGUL010000073 DAPGUL010000000
VERSION     DAPGUL010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22157
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.074"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(151..2418)
                     /gene="adiA"
                     /locus_tag="RHX21_002986"
     CDS             complement(151..2418)
                     /gene="adiA"
                     /locus_tag="RHX21_002986"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418541.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine decarboxylase"
                     /protein_id="HDV1988139.1"
                     /translation="MKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDG
                     FAILSSNEAIDCLMFSYQMEHPDEHQNVRQLIGKLHERQQNVPVFLLGDREKALAAMD
                     RDLLELVDEFAWILEDTADFIAGRAVAAMTRYRQQLLPPLFSALMKYSDIHEYSWAAP
                     GHQGGVGFTKTPAGRFYHDYYGENLFRTDMGIERTSLGSLLDHTGAFGESEKYAARVF
                     GADRSWSVVVGTSGSNRTIMQACMTDNDVVVVDRNCHKSIEQGLMLTGAKPVYMVPSR
                     NRYGIIGPIYPQEMQPETLQKKISESPLTKDKAGQKPSYCVVTNCTYDGVCYNAKEAQ
                     DLLEKTSDRLHFDEAWYGYARFNPIYADHYAMRGEPGDHNGPTVFATHSTHKLLNALS
                     QASYIHVREGRGAINFSRFNQAYMMHATTSPLYAICASNDVAVSMMDGNSGLSLTQEV
                     IDEAVDFRQAMARLYKEFTADGSWFFKPWNKEVVTDPQTGKTYDFADAPTKLLTTVQD
                     CWVMHPGESWHGFKDIPDNWSMLDPIKVSILAPGMGEDGELEETGVPAALVTAWLGRH
                     GIVPTRTTDFQIMFLFSMGVTRGKWGTLVNTLCSFKRHYDANTPLAQVMPELVEQYPD
                     TYANMGIHDLGDTMFAWLKENNPGARLNEAYSGLPMAEITPREAYNAIVDNNVELVSI
                     ENLPGRIAANSVIPYPPGIPMLLSGENFGDKNSPQVSYLRSLQSWDHHFPGFEHETEG
                     TEIIDGIYHVMCVKA"
     gene            complement(2617..3525)
                     /gene="melR"
                     /locus_tag="RHX21_002987"
     CDS             complement(2617..3525)
                     /gene="melR"
                     /locus_tag="RHX21_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator MelR"
                     /protein_id="HDV1988140.1"
                     /translation="MNTDTFMCSSDEKQTRSPLSLYSEYQRMEIEFRAPHIMPTSHWH
                     GQVEVNVPFDGDVEYLINNEKVNINQGHITLFWACTPHQLTDTGTCQSMAIFNLPMHL
                     FLSWPLDKDLINHVTHGMVIKSLATQQLSPFEVRRWQQELNSPNEQIRQLAIDEIGLM
                     LKRFSLSGWEPILVNKTSRTHKNSVSRHAQFYVSQMLGFIAENYDQALTINDVAEHVK
                     LNANYAMGIFQRVMQLTMKQYITAMRINHVRALLSDTDKSILDIALTAGFRSSSRFYS
                     TFGKYVGMSPQQYRKLSQQRRQTFPG"
     gene            3808..5163
                     /gene="melA"
                     /locus_tag="RHX21_002988"
     CDS             3808..5163
                     /gene="melA"
                     /locus_tag="RHX21_002988"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HDV1988141.1"
                     /translation="MMTAPKITFIGAGSTIFVKNILGDVFHREALKTAHIALMDIDPT
                     RLEESHIVVRKLMDSAGASGKITCHTQQKEALQDADFVVVAFQIGGYEPCTVTDFEVC
                     KRHGLEQTIADTLGPGGIMRALRTIPHLWQICEDMTEVCPDATMLNYVNPMAMNTWAM
                     YARYPHIKQVGLCHSVQGTAEELARDLNIDPATLRYRCAGINHMAFYLELERKTADGS
                     YVNLYPELLAAYEAGQAPKPNIHGNTRCQNIVRYEMFKKLGYFVTESSEHFAEYTPWF
                     IKPGREDLIERYKVPLDEYPKRCVEQLANWHKELEEYKNASRIDIKPSREYASTIMNA
                     IWTGEPSVIYGNVRNDGLIDNLPQGCCVEVACLVDANGIQPTKVGTLPSHLAALMQTN
                     INVQTLLTEAILTENRDRVYHAAMMDPHTAAVLGIDEIYALVDDLIAAHGDWLPGWLH
                     R"
     gene            5266..6687
                     /gene="melB"
                     /locus_tag="RHX21_002989"
     CDS             5266..6687
                     /gene="melB"
                     /locus_tag="RHX21_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418544.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="melibiose:sodium transporter MelB"
                     /protein_id="HDV1988142.1"
                     /translation="MSISMTTKLSYGFGAFGKDFAIGIVYMYLMYYYTDVVGLSVGLV
                     GTLFLVARIWDAINDPIMGWIVNATRSRWGKFKPWILIGTLANSVILFLLFSAHLFEG
                     TTQIVFVCVTYILWGMTYTIMDIPFWSLVPTITLDKREREQLVPYPRFFASLAGFVTA
                     GVTLPFVNYVGGGDRGFGFQMFTLVLIAFFIVSTIITLRNVHEVFSSDNQPSAEGSHL
                     TLKAIVALIYKNDQLSCLLGMALAYNVASNIITGFAIYYFSYVIGDADLFPYYLSYAG
                     AANLVTLVFFPRLVKSLSRRILWAGASILPVLSCGVLLLMALMSYHNVVLIVIAGILL
                     NVGTALFWVLQVIMVADTVDYGEYKLHVRCESIAYSVQTMVVKGGSAFAAFFIAVVLG
                     MIGYVPNVEQSTQALLGMQFIMIALPTLFFMVTLILYFRFYRLNGDTLRRIQIHLLDK
                     YRKVPPEPVHADIPVGAVSDVKA"
     gene            complement(6826..7455)
                     /locus_tag="RHX21_002990"
     CDS             complement(6826..7455)
                     /locus_tag="RHX21_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2238 domain-containing protein"
                     /protein_id="HDV1988143.1"
                     /translation="MTRTLKPLILNTGALALTLILIYTGISAHDKLTWLMEVTPVIIV
                     VPLLLATAKRYPLTPLLYTLIFFHAIILMVGGQYTYAKVPVGFEVQEWLGLSRNPYDK
                     LGHFFQGLVPALVAREILVRGMYVRGRKMVAFLVCCVALAISAMYELIEWWAALAMGQ
                     GADDFLGTQGDQWDTQSDMFCALLGALTTVIFLARFHCRQLRRFGLITG"
     gene            complement(7578..9224)
                     /gene="fumB"
                     /locus_tag="RHX21_002991"
     CDS             complement(7578..9224)
                     /gene="fumB"
                     /locus_tag="RHX21_002991"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fumarate hydratase"
                     /protein_id="HDV1988144.1"
                     /translation="MSNKPFIYQAPFPMGKDNTEYYLLTSDYVSVADFDGETILKVEP
                     EALTLLAQQAFHDASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVL
                     PTCQDTGTAIIVGKKGQRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAALDMYKEVNT
                     GTNLPAQIDLYAVDGDEYKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRT
                     LGTAACPPYHIAFVIGGTSAETNLKTVKLASAHYYDELPTEGNEHGQAFRDVQLEQEL
                     LEEAQKLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIW
                     IEKLEHNPGQYIPQELRQAGEGEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVG
                     RDIAHAKLKELIDAGKELPQYIKDHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDL
                     LQSHGGSMIMLAKGNRSQQVTDACHKHGGFYLGSIGGPAAVLAQQSIKHLECVAYPEL
                     GMEAIWKIEVEDFPAFILVDDKGNDFFQQIVNKQCANCTK"
     gene            complement(9302..10642)
                     /gene="dcuB"
                     /locus_tag="RHX21_002992"
     CDS             complement(9302..10642)
                     /gene="dcuB"
                     /locus_tag="RHX21_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuB"
                     /protein_id="HDV1988145.1"
                     /translation="MLFTIQLIIILICLFYGARKGGIALGLLGGIGLVILVFVFHLQP
                     GKPPVDVMLVIIAVVAASATLQASGGLDVMLQIAEKLLRRNPKYVSIVAPFVTCTLTI
                     LCGTGHVVYTILPIIYDVAIKNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVAMLG
                     NVTFDGRHLEFLDLLAITIPSTLIGILAIGIFSWFRGKDLDKDEEFQKFISVPENREY
                     VYGDTATLLDKKLPKSNWLAMWIFLGAIAVVALLGADSDLRPSFGGKPLSMVLVIQMF
                     MLLTGALIIILTKTNPASISKNEVFRSGMIAIVAVYGIAWMAETMFGAHMSEIQGVLG
                     EMVKEYPWAYAIVLLLVSKFVNSQAAALAAIVPVALAIGVDPAYIVASAPACYGYYIL
                     PTYPSDLAAIQFDRSGTTHIGRFVINHSFILPGLIGVSVSCVFGWIFAAMYGFL"
     gene            complement(11213..11932)
                     /gene="dcuR"
                     /locus_tag="RHX21_002993"
     CDS             complement(11213..11932)
                     /gene="dcuR"
                     /locus_tag="RHX21_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator DcuR"
                     /protein_id="HDV1988146.1"
                     /translation="MINVLIIDDDAMVAELNRRYVAQIPGFQCCGTASTLEKAKEIIF
                     NSDTPIDLILLDIYMQKENGLDLLPVLHNARCKSDVIVISSAADAATIKDSLHYGVVD
                     YLIKPFQASRFEEALTGWRQKKMALEKHQYYDQAELDQLIHGSSSNEQDPRRLPKGLT
                     PQTLRTLCQWIDAHQDYEFSTDELANEVNISRVSCRKYLIWLVNCHILFTSIHYGVTG
                     RPVYRYRIQAEHYSLLKQYCQ"
     gene            complement(11929..13560)
                     /gene="dcuS"
                     /locus_tag="RHX21_002994"
     CDS             complement(11929..13560)
                     /gene="dcuS"
                     /locus_tag="RHX21_002994"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     DcuS"
                     /protein_id="HDV1988147.1"
                     /translation="MRHSLPYRMLRKRPMKLSTTVILMVSAVLFSVLLVVHLIYFSQI
                     SDMTRDGLANKALAMARTLADSPEIRQGLQKKPQESGIQAIAEAVRKRNDLLFIVVTD
                     MQSLRYSHPEAQRIGQPFKGDDILKALNGKENVAINRGFLAQALRVFTPIYDENHKQI
                     GVVAIGLELSRVTQQINDSRWSIIWSVLFGMLVGLIGTCILVKVLKKILFGLEPYEIS
                     TLFEQRQAMLQSIKEGVVAVDDRGEVTLINDAAQELLNYRKSQDDEKLSTLSHSWSQV
                     VDVSEVLRDGTPRRDEEITIKDRLLLINTVPVRSNGVIIGAISTFRDKTEVRKLMQRL
                     DGLVNYADALRERSHEFMNKLHVILGLLHLKSYKQLEDYILKTANNYQEEIGSLLGKI
                     KSPVIAGFLISKINRATDLGHTLILNSESQLPDSGSEDQVATLITTLGNLIENALEAL
                     GPEPGGEISVTLHYRHGWLHCEVNDDGPGIAPDKIDHIFDKGVSTKGSERGVGLALVK
                     QQVENLGGSIAVESEPGIFTQFFVQIPWDGERSNR"
     gene            13741..13971
                     /locus_tag="RHX21_002995"
     CDS             13741..13971
                     /locus_tag="RHX21_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HDV1988148.1"
                     /translation="MDQALLDEGYRCYTGEKIDVYFNTAICQHSGNCVRGNGKLFNLK
                     RKPWIMPDEVDVATVVKVIDTCPSGALKYRHK"
     gene            13983..14255
                     /locus_tag="RHX21_002996"
     CDS             13983..14255
                     /locus_tag="RHX21_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDV1988149.1"
                     /translation="MEIREGHNKFYINDEQGKQIAEIVFVPTGENLAIIEHTDVDESL
                     KGQGIGKQLVAKVVEKMRREKRKIIPLCPFAKHEFDKTREYDDIRS"
     gene            14482..14778
                     /gene="ghoS"
                     /locus_tag="RHX21_002997"
     CDS             14482..14778
                     /gene="ghoS"
                     /locus_tag="RHX21_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system endoribonuclease
                     antitoxin GhoS"
                     /protein_id="HDV1988150.1"
                     /translation="MEGKNKFNTYVVSFDYPSSYSSVFLRLRSLMYDMNFSSIVADEY
                     GIPRQLNENSFAITTSLAASEIEDLIRLKCLDLPDIDFDLNIMTVDDYFRQFYK"
     gene            14806..14979
                     /gene="ghoT"
                     /locus_tag="RHX21_002998"
     CDS             14806..14979
                     /gene="ghoT"
                     /locus_tag="RHX21_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system toxin GhoT"
                     /protein_id="HDV1988151.1"
                     /translation="MALFSKILIFYVIGVNISFVIIWFISHEKTHIRLLSAFLVGITW
                     PMSLPVALLFSLF"
     gene            complement(15098..16615)
                     /gene="lysS"
                     /locus_tag="RHX21_002999"
     CDS             complement(15098..16615)
                     /gene="lysS"
                     /locus_tag="RHX21_002999"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HDV1988152.1"
                     /translation="MSEQETRGANEAIDFNDELRNRREKLAALRQQGVAFPNDFRRDH
                     TSDQLHEEFDAKDNQELESLNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARD
                     SLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGL
                     QDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGA
                     SARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFT
                     MMELYMAYADYHDLIELTESLFRTLAQEVLGTTKVTYGEHVFDFGKPFEKLTMREAIK
                     KYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITE
                     YPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAG
                     DDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMRPQK"
     gene            complement(16852..18309)
                     /gene="dtpC"
                     /locus_tag="RHX21_003000"
     CDS             complement(16852..18309)
                     /gene="dtpC"
                     /locus_tag="RHX21_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpC"
                     /protein_id="HDV1988153.1"
                     /translation="MKTPSQPRAIYYIVAIQIWEYFSFYGMRALLILYLTHQLGFDDN
                     HAISLFSAYASLVYVTPILGGWLADRLLGNRTAVIAGALLMTLGHVVLGIDTNSTFSL
                     YLALAIIICGYGLFKSNISCLLGELYDENDHRRDGGFSLLYAAGNIGSIAAPIACGLA
                     AQWYGWHVGFALAGGGMFIGLLIFLSGHRHFQSTRSMDKKALTSVKFALPVWSWLVVM
                     LCLAPVFFTLLLENDWSGYLLAIVCLIAAQIIARMMIKFPEHRRALWQIVLLMFVGTL
                     FWVLAQQGGSTISLFIDRFVNRQAFNIEVPTALFQSVNAIAVMLAGVVLAWLASPESR
                     GNSTLRVWLKFAFGLLLMACGFMLLAFDARHAAADGQASMGVMISGLALMGFAELFID
                     PVAIAQITRLKMSGVLTGIYMLATGAVANWLAGVVAQQTTESQISGMAIAAYQRFFSQ
                     MGEWTLACVAIIVVLAFATRFLFSTPTNMIQESND"
     gene            complement(18368..20515)
                     /gene="cadA"
                     /locus_tag="RHX21_003001"
     CDS             complement(18368..20515)
                     /gene="cadA"
                     /locus_tag="RHX21_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylase CadA"
                     /protein_id="HDV1988154.1"
                     /translation="MNVIAILNHMGVYFKEEPIRELHRALERLNFQIVYPNDRDDLLK
                     LIENNARLCGVIFDWDKYNLELCEEISKMNENLPLYAFANTYSTLDVSLNDLRLQISF
                     FEYALGAAEDIANKIKQTTDEYINTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQK
                     SPVGSLFYDFFGPNTMKSDISISVSELGSLLDHSGPHKEAEQYIARVFNADRSYMVTN
                     GTSTANKIVGMYSAPAGSTILIDRNCHKSLTHLMMMSDVTPIYFRPTRNAYGILGGIP
                     QSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKKTLDVKSIHFDSAWV
                     PYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHKLLAAFSQASMIHVKGDVNEETFNEA
                     YMMHTTTSPHYGIVASTETAAAMMKGNAGKRLINGSIERAIKFRKEIKRLRTESDGWF
                     FDVWQPDHIDTTECWPLRSDSTWHGFKNIDNEHMYLDPIKVTLLTPGMEKDGTMSDFG
                     IPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAFDLNLRV
                     KNMLPSLYREDPEFYENMRIQELAQNIHKLIVHHNLPDLMYRAFEVLPTMVMTPYAAF
                     QKELHGMTEEVYLDEMVGRINANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEI
                     GAHYPGFETDIHGAYRQADGRYTVKVLKEESKK"
     gene            complement(20595..21929)
                     /gene="cadB"
                     /locus_tag="RHX21_003002"
     CDS             complement(20595..21929)
                     /gene="cadB"
                     /locus_tag="RHX21_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadaverine/lysine antiporter"
                     /protein_id="HDV1988155.1"
                     /translation="MSSAKKIGLFACTGVVAGNMMGSGIALLPANLASIGGIAIWGWI
                     ISIIGAMSLAYVYARLATKNPQQGGPIAYAGEISPAFGFQTGVLYYHANWIGNLAIGI
                     TAVSYLSTFFPVLNDPVPAGIACIAIVWVFTFVNMLGGTWVSRLTTIGLVLVLIPVVM
                     TAIVGWHWFDAATYAANWNTADTTDGHAIIKSILLCLWAFVGVESAAVSTGMVKNPKR
                     TVPLATMLGTGLAGIVYIAATQVLSGMYPSSVMAASGAPFAISASTILGNWAAPLVSA
                     FTAFACLTSLGSWMMLVGQAGVRAANDGNFPKVYGEVDSNGIPKKGLLLAAVKMTALM
                     ILITLMNSAGGKASDLFGELTGIAVLLTMLPYFYSCVDLIRFEGVNIRNFVSLICSVL
                     GCVFCFIALMGASSFELAGTFIVSLIILMFYARKMHERQSHSMDNHTASNAH"
BASE COUNT         5614 a         5302 c         5550 g         5691 t
ORIGIN      
        1 acaggcaaaa aaaagcgcgg ggtggggccg cgcaaaaagt atgacatttt tgtttgcagc
       61 aatttttatg aaaacgttgc catactcaaa aggcctaagg ccaggcggcg taatgttatt
      121 taaacaatta cgccttcagc ggaatagtgg ttacgctttc acgcacataa cgtggtaaat
      181 accgtcaata atttcagtcc cttcagtttc gtgttcaaat ccagggaaat ggtggtccca
      241 ggattgcagc gagcgtaaat aacttacttg cggactgttt ttatcgccga agttttcacc
      301 agacagcagc atcgggattc ctggcggata cgggataact gagtttgccg cgatgcgtcc
      361 tggcagattt tcaatggata ccagttcgac attgttgtcg acaatcgcgt tgtacgcttc
      421 acgcggggtg atttccgcca tcggcaggcc ggaataggct tcgttcaacc gtgcgccagg
      481 gttgttttct ttcagccagg caaacatggt gtcacccaga tcgtgaatcc ccatgttcgc
      541 gtaagtgtca ggatattgtt caacaagttc cggcatcacc tgcgccagcg gtgtgttggc
      601 gtcatagtgg cgtttgaagg agcaaagggt gttaaccaga gtcccccatt tcccacgggt
      661 tacgcccata gagaacagga acataatttg gaagtcagtg gtgcgggtag gcacaatgcc
      721 gtggcgacca agccaggcag tgaccagcgc cgccggaaca ccggtttctt ccagttcacc
      781 atcttcaccc attcccggag caaggatgct gactttaatc gggtcgagca tactccagtt
      841 atccggaata tctttgaagc cgtgccagct ttcgcccgga tgcattaccc agcagtcctg
      901 aacggtggtc agcagtttgg ttggtgcgtc agcaaagtca taggttttgc cggtttgtgg
      961 gtcggtgacg acttctttgt tccacggttt gaagaaccag ctaccgtcag cggtgaactc
     1021 tttatacagc cgcgccatcg cctgacggaa atcaaccgct tcgtcgatca cttcctgcgt
     1081 cagtgacagg ccgctgttgc cgtccatcat cgacaccgcc acgtcgttgg atgcgcagat
     1141 ggcatacagc ggggaggtgg tggcatgcat catgtaggcc tggttaaagc gggagaagtt
     1201 aatcgcccca cgaccttcac gtacatgaat ataagaagcc tgtgaaagcg cattcagcag
     1261 tttgtgggtg gagtgggtgg cgaaaacggt aggaccgttg tgatcgccag gttcgccgcg
     1321 catggcatag tgatcggcat agatcgggtt gaaacgtgca tagccgtacc aggcttcgtc
     1381 aaagtgcaga cgatcggagg ttttttccag cagatcctgc gcttctttag cgttataaca
     1441 cacgccgtca taggtgcagt tggtcaccac gcagtaagac ggtttttgcc cagctttgtc
     1501 tttagtcagc gggctttcac tgattttctt ctgcaaggtt tcaggttgca tttcctgcgg
     1561 atagattggc ccgataatgc cgtagcggtt gcggcttggc accatgtaga ctggtttcgc
     1621 gcctgtcagc atcaagcctt gttcgatgga tttatggcaa ttacggtcaa cgaccacgac
     1681 atcgttatcg gtcatgcaag cctgcatgat ggtgcggtta gagccggaag taccgacgac
     1741 taccgaccag gagcgatcgg caccaaatac gcgtgcggca tatttttcgc tttcgccaaa
     1801 tgcgccagta tggtcaagca aagaaccgag ggaagttcgt tcgatgccca tatcggtgcg
     1861 gaacagattt tctccatagt agtcatggta gaaacgtccg gcgggtgttt tggtaaaacc
     1921 aacgccgccc tggtggcctg gcgctgccca ggaatattca tggatgtcgc tatatttcat
     1981 cagcgcgctg aacagtggcg gcaacagctg ctggcggtag cgggtcatcg cggcaacagc
     2041 gcgtccggcg ataaagtcgg cggtatcttc cagaatccag gcgaattcat cgacaagctc
     2101 cagcaggtcg cgatccattg cggcgagggc tttttcccga tcgcccaaca ggaagaccgg
     2161 cacgttttgt tggcgctcat gaagcttacc gatcaattgt ctgacgtttt gatgttcgtc
     2221 cggatgttcc atttgataac tgaacatcag gcagtcaatg gcttcgtttg aagagagaat
     2281 ggcaaaacca tcatcaaagg aggtggattt aatcacggta acattttgct ggcttaaagc
     2341 atctgccaga cgctcaacgg cgttaccgac ccaggtgtct tgatggagaa actcgctttc
     2401 aacaattaat actttcatca ttgcttaccc ggttatgaag gaatcttcgt tgcgggcaag
     2461 tatcttccgg ccttttcggg ctgtaaagcg cgtgaaaaac aaacattttt gaaatattta
     2521 tttttataaa caatgcgtta tgtgattatt ttaaattatt ttcactgctt attatcgacg
     2581 gctaaactat ttttttggct gatactgata tcgtctttag ccgggaaacg tctggcggcg
     2641 ctgttggcta agtttgcggt attgttgcgg cgacatgccg acatatttgc cgaacgtgct
     2701 gtaaaaacga ctacttgaac gaaagcctgc cgtcagggca atatcgagaa tacttttatc
     2761 ggtatcgctc agtaacgcgc gaacgtggtt gatgcgcatc gcggtaatgt actgtttcat
     2821 cgtcaattgc atgacccgct ggaatatccc cattgcatag ttggcgttaa gtttgacgtg
     2881 ctcagccaca tcgttgatgg tcagcgcctg atcatagttt tcggcaataa agcccagcat
     2941 ctggctaaca taaaattgcg catggcgcga gacgctgttt ttgtgtgtgc gcgaggtttt
     3001 attgaccaga atcggttccc agccagagag gctaaatcgc ttgagcatca ggccaatttc
     3061 atcaatggcg agctggcgaa tttgctcgtt cggactgttt aattcctgct gccagcggcg
     3121 cacttcaaac gggctaagtt gctgtgtggc cagtgatttg atcaccatgc cgtgagtgac
     3181 gtggttaatc aggtctttat ccagcggcca ggagagaaac agatgcatcg gcagattaaa
     3241 aatcgccatg ctctgacagg ttccggtatc tgttagttgg tgcggtgtac aggcccagaa
     3301 cagcgtgata tgaccctgat tgatattcac tttttcattg ttgatcaggt attccacatc
     3361 gccatcgaaa ggcacattca cttcgacctg accatgccag tggctggtgg gcatgatatg
     3421 cggtgcgcga aactcaatct ccatccgctg gtattccgaa tacagcgaca gcgggctgcg
     3481 ggtctgtttt tcgtcgctgc tgcacataaa cgtatctgta ttcatggatg gctctctttc
     3541 ctggaatatc agaattatgg caggagtgag ggaggatgac tgcgagtggg agcacggttt
     3601 tcaccctctt cccagagagg cgaggggagc gtccgagcat catgaggccg aaaactctgc
     3661 ttttcaggta acttattacc ataaactcag atttactgct gcttcacgca ggatctgagt
     3721 ttatgggaat gctcaacctg gaagccggag gttttctgca gattcgcctg ccatgatgaa
     3781 gttattcaag caagccagga gatctgcatg atgactgcac ccaaaattac atttatcggc
     3841 gctggttcga cgattttcgt taaaaatatt cttggtgatg tgttccatcg cgaggcgctg
     3901 aaaacggcgc atattgccct gatggacatt gatcctaccc gcctggaaga gtcgcatatt
     3961 gtggtgcgta agcttatgga ttcagcaggg gccagcggca aaatcacctg ccacacccaa
     4021 cagaaagaag ccttacagga tgccgatttt gtcgtggtgg catttcagat tggcggttat
     4081 gaaccttgca cggtgactga tttcgaggtc tgtaagcggc atggtctgga acaaaccatt
     4141 gccgatacgt tggggccggg cggtattatg cgcgcgctac gtaccattcc gcatctgtgg
     4201 caaatttgcg aggacatgac ggaagtctgc cccgatgcca ccatgctcaa ctatgttaac
     4261 ccaatggcga tgaatacctg ggcgatgtat gcccgctatc cgcatatcaa acaggtcggg
     4321 ctgtgccatt cggtgcaggg aacggcggaa gagctggcgc gtgacctcaa tatcgaccca
     4381 gctacgctgc gttaccgttg cgcaggtatc aaccatatgg cgttttacct ggagctggag
     4441 cgcaaaaccg ccgacggcag ttatgtgaat ctctacccgg aactgctggc ggcttatgaa
     4501 gcagggcagg caccgaagcc gaatattcat ggcaatactc gctgccagaa tattgtgcgc
     4561 tacgaaatgt tcaaaaagct gggctacttc gtcacggaat cgtcagaaca ttttgctgag
     4621 tacacaccgt ggtttattaa gccaggtcgt gaggatttga ttgagcgtta taaagtaccg
     4681 ctggatgagt acccgaaacg ctgcgtcgag cagctggcga actggcataa agagctggag
     4741 gagtataaaa acgcctcccg gattgatatt aaaccgtcac gggaatatgc cagcacaatc
     4801 atgaacgcta tctggactgg cgagccgagt gtgatttacg gcaacgtccg taacgatggt
     4861 ttgattgata acctgccaca aggatgttgc gtggaagtag cctgtctggt tgatgctaat
     4921 ggcattcagc cgaccaaagt cggtacgcta ccttcgcatc tggccgccct gatgcaaacc
     4981 aacatcaacg tacagacgct gctgaccgaa gctattctta cggaaaatcg cgaccgtgtt
     5041 taccacgccg cgatgatgga cccgcatact gctgccgtgc tgggcattga tgaaatatat
     5101 gctcttgttg acgacctgat tgccgcccac ggcgactggc tgccaggctg gttgcaccgt
     5161 taaaacgcga ctaaacgcta ctgcgccggg ggatttattc cggcgcacac ctctgacgat
     5221 accaataaca gaaggcgggc gttggtaaca gcgacccgat accctatgag catttcaatg
     5281 actacaaaac tcagttatgg atttggagcg ttcgggaagg attttgcgat cggcattgtg
     5341 tatatgtacc tcatgtatta ctacaccgat gtcgttgggc tgtctgtggg tttggtcggt
     5401 actttgtttc tggtggcgag gatctgggat gctattaacg atccgattat gggatggatt
     5461 gtaaatgcta cgcgatcgcg atggggtaag ttcaaaccct ggatcctgat cggtacgttg
     5521 gcaaactctg taatcttatt tctcctcttt agtgcgcatc tgtttgaagg tactactcag
     5581 attgtctttg tttgcgtgac ctacatcctc tggggcatga cttacaccat tatggatatt
     5641 cccttctggt cgctggttcc aaccatcacg ctcgataaac gtgagcgcga acaactggtt
     5701 ccttatccgc gtttttttgc cagtctggca ggctttgtta cggcaggtgt gacgctacca
     5761 tttgttaatt atgtcggcgg tggcgatcgg ggatttggct ttcagatgtt cactctggta
     5821 ctaatcgcct tttttattgt ttcaaccatc atcactctgc gcaatgtgca tgaagtcttt
     5881 tcgtcagaca atcaaccgtc tgctgaagga agccatctga cacttaaagc catcgttgcg
     5941 ctaatttata aaaacgatca gctttcatgc ctcttgggta tggctcttgc ttataatgta
     6001 gccagcaaca ttattaccgg atttgctatc tattatttct catatgttat cggtgatgcg
     6061 gatttgttcc cctattatct gtcgtatgcg ggagctgcta acctggtgac gttagtattc
     6121 ttcccacgct tagttaaatc attatcccga cgcattttat gggccggagc atctattctt
     6181 ccggtgttaa gctgtggtgt tctcctgtta atggcattaa tgagctatca caacgtcgtc
     6241 ctcattgtga ttgcgggtat tttgctgaat gtgggaacgg cgcttttctg ggtattacag
     6301 gtcatcatgg tggcagatac cgttgattac ggtgaatata aactgcacgt acgctgtgaa
     6361 agtatcgctt actccgtgca gactatggtg gtgaagggcg gttcagcctt tgcggctttt
     6421 ttcattgcgg ttgtgttagg gatgattggc tatgtaccga atgttgaaca gtctacgcaa
     6481 gccctattag gtatgcagtt tattatgatt gctctaccaa ctctgttttt catggtaacg
     6541 ctgattctct acttccgttt ctatcgcctc aatggcgaca cgctgcgcag gatccagatt
     6601 catctgctgg ataaatatcg caaagtaccg cccgagcctg ttcatgctga tattccggtc
     6661 ggtgcagtga gtgatgtgaa agcctgacgt ggacaatagc taacgaaaat ggcctgatgc
     6721 gatatgttta tcaggccacg tcttaatgta atgctttgga tttgcaaatt ttgtagaccg
     6781 gataaggaat tcacgccgca tccggcatca acaaagcgca cgttgttatc cggttatcaa
     6841 gccaaagcgc cgtagctggc ggcaatgaaa gcgagcgagg aatatcaccg tcgttaatgc
     6901 gccaagcagc gcgcagaaca tatcggattg cgtgtcccac tggtcgccct gggtgccgag
     6961 aaaatcatcc gctccctggc ccattgccag cgccgcccac cactcgatta attcatacat
     7021 cgcgcttatc gccagcgcca cgcagcagac caggaacgcc accattttac gtccgcgcac
     7081 gtacatcccg cgaacgagaa tttctcgtgc caccagtgca ggcaccagcc cctggaaaaa
     7141 atgccccagc ttgtcatacg gattacggct caaccctaac cattcctgca cctcaaaacc
     7201 aacggggact ttcgcgtagg tgtattgtcc gccgaccatc aggatgatgg cgtgaaagaa
     7261 aatgagcgta tagagcagcg gcgttaacgg ataacgtttc gcggtggcaa ggagtagcgg
     7321 cacgacaata atcaccggtg tcacttccat cagccaggtg agtttgtcat gggccgaaat
     7381 gccggtataa atcaggatta acgttagcgc cagtgcgccg gtgttaagaa ttaacggctt
     7441 gagtgtgcgg gtcatggtga gttcgcaagt cagggaaaat actgactatt caccagcaag
     7501 cgtgaaatta caatcgcaaa agaggtggcc cagggggatc acctggcagc atgctgccag
     7561 gcgctgggcc gaagaggtta cttagtgcag ttcgcgcact gtttgttgac gatctgctgg
     7621 aagaagtcgt tacctttgtc atcgaccagg ataaacgccg ggaaatcttc tacttcgatt
     7681 ttccagatag cttccatacc cagctccgga taagcgacgc attccagatg cttgatgctc
     7741 tgctgcgcca gtaccgccgc cggaccgccg atgctaccga ggtagaagcc gccgtgttta
     7801 tgacacgcgt cggtaacctg ctgactgcgg ttacctttcg ccagcatgat catgctgccg
     7861 ccgtgggatt gcagcagatc cacgtaggag tccatacggc ctgcggtggt tgggccaagt
     7921 gaacctgatg gataaccggc aggggttttc gccggacccg cgtagtagat cgggtgatct
     7981 ttgatgtact gcggaagttc tttaccggcg tcaatcagct ctttcagctt ggcgtgtgca
     8041 atatctcggc ccacgataat ggtgccggtg agcgacaaac gagtggatac cgggtattgc
     8101 gaaagctggg cgaggatctc tttcatcggg cggttaaggt caactttcac cgcttcgcct
     8161 tcaccggcct ggcgcagttc ttgtggaatg tactggcctg ggttgtgttc cagtttttcg
     8221 atccagatac cttcgcggtt gattttcgct ttaatgttac ggtcagcgga gcaggagacg
     8281 cccatgccga ccgggcagga tgcgccgtga cgtggcagac ggataacgcg aatgtcgtgc
     8341 gcgaagtatt taccgccaaa ctgcgcgcca agaccgagtt tctgggcctc ttccagcagt
     8401 tcctgttcca gctggacatc gcggaacgcc tgaccatgtt cgttcccttc cgtcggcagt
     8461 tcatcgtaat agtgagcgct tgctaacttg acggttttca ggttggtttc cgcagacgta
     8521 ccgccaatca caaacgcgat atggtacggc gggcaggctg cagtaccgag ggtacgcatt
     8581 ttctcgacga ggaagttttt cagtttgccg ggagtcagca gggctttggt ttcctggtag
     8641 agatacgttt tgttggcaga gccgccgcct ttcgcaacgc aaaggaattt gtactcatcg
     8701 ccatctaccg cgtacaggtc gatttgcgca ggcaggttag tgccggtgtt gacctctttg
     8761 tacatgtcca gcgccgcatt ctgtgaatag cgcaggttat cttcgatata ggtgttatag
     8821 acgcctttcg acagcgcttc ttcatcaccg ccgccggtcc acacgcgctg gcctttttta
     8881 ccgacgatga tcgcggtgcc ggtatcctgg caggtcggca gcacgccttt ggcggcgatt
     8941 tcggagtttc ttaagaattg cagcgccacg tacttgtcgt tttcgctggc ttctggatcg
     9001 tgaagaatag ccgcaacctg tttctggtgt gccgggcgga gcataaaaga agcgtcgtga
     9061 aaggcttgct gcgccagcag ggtcagggct tctggttcca ctttcaggat ggtttcgccg
     9121 tcgaagtcgg caacgctaac gtaatcggaa gtgagtagat agtattcggt attgtctttc
     9181 cccatcggga aaggtgcctg gtagataaag ggtttgtttg acatagcttc cagcctgtaa
     9241 ctctgtattt gttattcgaa aatggcgtgc cgcgtagtca cgggcggcac gcaaagtgca
     9301 tttataagaa cccgtacatc gcggcgaaga tccagccgaa gacgcacgat acgctcacac
     9361 caatcaaccc cggcagaata aagctgtggt tgatgacgaa gcgaccgatg tgggtggtgc
     9421 cggaacggtc aaactgaatc gctgccagat cgctcggata agtcggcagg atgtaataac
     9481 cgtagcaagc cggtgctgaa gccacgatgt atgccggatc aacgccgatc gccagcgcga
     9541 ccggaacaat cgccgccagc gccgcagcct gagagtttac aaacttggaa accagcagca
     9601 gaacaatggc ataggcccac ggatactctt tcaccatttc acccagtacg ccctgaattt
     9661 cagacatatg cgcaccgaac atggtttctg ccatccatgc gataccgtac accgccacga
     9721 tggcgatcat accggaacgg aagacttcgt tttttgagat agacgcggga ttggttttgg
     9781 tcaggataat aatcagcgcc ccggtcagca gcataaacat ctgaataacc agtaccatcg
     9841 acagcggttt gccgccgaag gatggacgca ggtccgaatc agcaccaaga agggcgacta
     9901 cagcgattgc accgaggaaa atccacattg ccagccagtt gcttttcggc agttttttat
     9961 cgagcagcgt cgcggtatca ccgtaaacat actcacggtt ttccggtacg gagatgaatt
    10021 tctggaactc ttcgtcttta tccagatctt taccgcggaa ccagctgaag ataccgatcg
    10081 ccaggatacc gattaacgtc gatggaatgg tgattgccag caggtcgagg aactcaagat
    10141 ggcgaccatc aaaggtgaca ttacccagca ttgcaaccag agacacgacc gcaaccgaca
    10201 ccggactggc gataatcccc atctgtgcac cgatagaact tgccgccatc ggacgttccg
    10261 gacggatgtt gttcttaatg gcgacgtcgt agatgatcgg cagaatggtg taaaccacat
    10321 gacccgtacc gcaaagaatg gtcagtgtac aggtcacaaa cggcgcgaca attgagacat
    10381 atttcgggtt gcggcgcagc aacttctcgg caatttgcag catgacatca agaccgcccg
    10441 aagcttgcaa ggtcgccgat gccgccacca ccgcaatgat aaccagcatg acatcaactg
    10501 gtggtttacc tggctgaagg tggaagacga agaccagaat gaccagaccg ataccgccta
    10561 ataaacccag cgcgatacca ccctttctgg caccataaaa cagacatatc agtattatga
    10621 taagttggat agtaaataac atgtgtgaac cctcgcgata atcctattta aatttttgct
    10681 gaatagatca cagtcacgtt ctgttttgta tgaactgttt tcagagcctg actaaatatc
    10741 cgtttggtcg ttaccggctt tagcaaatac ctcacagtaa atattggctg attaaagcag
    10801 cggcaaattt atgcactgtg ataagcggct ttttcagaga gaaaaactct ctggcgatgg
    10861 gtttatagtt tgtactgcgc agatgttaat gttttgtttg ctgttatctt attgatattt
    10921 atcggtctat tttttgttct cagggcagat atcattaggt ttaaagatta atctgatcta
    10981 cccatttgtg ggtaaaaata cacataatgc gggtgacata atagttaatt aacttttgtt
    11041 agcgttttga aattaaaaac accgttcacc tgaagagata ttaattttta gcgatgatgg
    11101 agggataatt atatttgatc tggcacaagt tttactgatg aaggatgtaa cttgtgccag
    11161 gggtattttg cattacggta ataattatta cttacagata accagcgatc cgttattggc
    11221 aatattgttt cagcagtgag tagtgttctg cctgaatacg gtaacggtaa accggacgcc
    11281 ccgtgacgcc ataatggata ctggtgaaca agatgtggca gttgaccagc cagatgaggt
    11341 attttcggca ggaaacacgc gagatgttaa cctcgttagc cagctcgtcg gttgaaaact
    11401 catagtcctg atgcgcgtca atccactggc acagcgtgcg taacgtctgc ggcgttaagc
    11461 cttttggcaa gcgacgagga tcctgttcgt tggagctgct gccgtggatt agctgatcaa
    11521 gctcggcctg gtcataatac tgatgttttt ccagcgccat tttcttttgc cgccagccgg
    11581 tgagcgcctc ttcaaagcgg gaagcctgga agggtttgat caggtaatcc acgacaccgt
    11641 aatgcagcga atctttaatg gttgccgcat cggctgcgga ggagatgaca atcacatcac
    11701 ttttgcaacg cgcgttatgc aggacaggca gtaaatcgag cccgttctct ttttgcatat
    11761 agatatcgag caatatcagg tcgataggcg tatcgctatt gaagataatc tctttggctt
    11821 tctccagcgt cgaggctgtt ccacagcatt gaaagcctgg gatttgtgct acgtatcggc
    11881 gattcagctc cgcgaccatt gcgtcgtcat cgataattaa tacattgatc atctgttcga
    11941 cctctccccg tcccagggta tctggacaaa aaattgtgtg aaaatcccgg gttccgattc
    12001 cacggcgatg ctgccgccga gattttctac ctgttgtttg acaagtgcta aaccgacgcc
    12061 tcgctcgctt ccttttgtcg agacaccttt gtcaaaaatg tgatcgattt tgtcgggtgc
    12121 gatccccggt ccatcatcgt taacttcgca gtgcagccag ccgtgacggt agtgcaatgt
    12181 tacgctaatt tcgccaccgg gttccggccc taatgcttcc agcgcgtttt ctatcagatt
    12241 tcccaatgtg gtaatcagcg tcgcgacctg gtcctcactg ccgctgtctg gcagctggct
    12301 ttcactgttt aaaatcagcg tatggcctaa atcggtcgcg cggttaatct tgctgattaa
    12361 aaaaccagcg ataaccggag atttgatctt acccagcaga gagccaatct cttcctgata
    12421 gttattggct gttttgagaa tgtaatcttc caactgctta taactcttca gatgcaataa
    12481 tccgagaatc acatgcaatt tattcataaa ttcgtgggat cgttcacgaa gtgcatcagc
    12541 atagttgacc agaccgtcga gtcgctgcat cagtttacga acttcagttt tgtccctgaa
    12601 ggttgaaatg gcaccgatga taacgccatt actgcgcacc ggaacggtgt tgatcagtaa
    12661 tagccggtct ttaatcgtaa tctcttcgtc gcggcgcggc gtaccgtcgc gtaacacttc
    12721 cgagacatct accacctgtg accatgagtg gcttagcgtc gacagtttct catcgtcctg
    12781 cgacttacgg taattcagca attcttgtgc ggcatcgttg atcagcgtga cctcgccgcg
    12841 atcgtccacg gcaacgacgc cttctttgat agactgcaac atggcctggc gttgctcaaa
    12901 cagcgtggag atttcgtagg gttccaggcc gaaaaggatt tttttcagta ccttaaccag
    12961 aatgcaggtg ccaatcagtc cgaccagcat gccaaataat accgaccaga taatgctcca
    13021 gcgactgtca ttgatttgtt gggtcacgcg gcttaactca aggccgatcg ccaccacgcc
    13081 aatttgttta tgattttcat cgtagatggg ggtaaatacg cgtaaagcct gtgccagaaa
    13141 accgcgattg atagcgacat tttctttgcc attcagcgct ttaaggatgt catcaccttt
    13201 aaatggctga ccaatacgct gggcttcagg atgcgagtag cgaagacttt gcatatcggt
    13261 aacgacaata aacagcagat cgttgcgttt gcgcacggct tccgcgatgg cctggattcc
    13321 gctctcctgc ggttttttct gcaagccctg acggatttcc ggcgagtcgg cgagggtacg
    13381 cgccattgcc agtgccttgt tggccagccc gtctcgcgtc atatcactga tttgcgagaa
    13441 gtaaatcaga tgcaccacca atagcaccga gaacagtacc gcgctgacca ttaagatcac
    13501 tgtggtactc aatttcatcg gacgtttgcg taacatgcgg tagggcaatg aatgtctcat
    13561 cagcttcctt gtgtgacaaa tttcttaagc attatctctg atgaggcggg taattcaaag
    13621 ggagtaagaa tgattggcta tataggggaa gagactctgg caacggaaac tgccagtgct
    13681 gtatgaagat tccagggcta tgcttatagc gataatcata ctgatgagag agggaaagtc
    13741 atggatcagg cgctactgga cgagggttat cgctgttata ccggcgaaaa gatcgatgtc
    13801 tatttcaaca ctgcgatatg tcagcattct ggcaattgcg tacgtggcaa cggcaagtta
    13861 tttaatctca aacgaaagcc gtggatcatg ccggatgaag tcgacgttgc cactgtggtg
    13921 aaagtgattg atacgtgccc gagtggtgcg ctgaaatacc gtcataaata agcgagggta
    13981 aaatggaaat acgcgaaggc cacaataaat tttacattaa tgacgaacag ggcaagcaaa
    14041 tcgctgaaat tgtctttgtg ccgaccggag agaatttagc gattatcgaa cataccgatg
    14101 tcgatgaaag cctgaaaggg caggggattg gtaaacagct ggttgcgaaa gtcgtggaaa
    14161 aaatgcgtcg ggaaaaacga aaaattatcc cactatgccc atttgcgaaa cacgaatttg
    14221 ataaaacgcg ggagtatgat gatattcgca gttgatggga gagtacagag tcacgatatt
    14281 tttcatgctc tccgcggagt gatgcaggag agcatctgaa gggtaggggg atgcacaaag
    14341 aatgggcaga gagcgcgttt ttttgtccca agtcatcccc tttactgagc aaaaaaaaga
    14401 atatctccta tatgagaatc atcaatcggg gttaataatt tttgcgtccc cagagcattc
    14461 aatattgata ggagtcatat tatggaaggt aaaaacaagt tcaatactta tgttgtttct
    14521 tttgattatc catcatctta ttcctcagtg ttcttaaggt taagatcatt gatgtatgat
    14581 atgaatttct cttctatcgt ggctgatgaa tatgggatac cacgacaatt gaatgaaaat
    14641 tctttcgcaa taacgacatc gttagccgca agtgaaatcg aagatttaat caggcttaaa
    14701 tgcttagact taccggatat tgattttgac ctcaacatta tgacagttga tgactatttc
    14761 cgtcagtttt acaagtagcc aggaaggata agaagaacat aaaaaatggc actattctct
    14821 aaaatattaa ttttttatgt gattggtgtg aacatatcct ttgtcattat ctggtttatc
    14881 tcacatgaga aaacacatat tcgtttactt agtgcattcc tggtcggaat aacctggcca
    14941 atgagtctgc ctgtggcatt acttttttct ctcttttagg agctgtagtt gagtggaccc
    15001 gctggttatc gtgaaacgaa gcgtctctcc tcaaaactgg atttgcggaa cgacgaacga
    15061 agcagtcgcc tgactgcttc gttcattaaa gtgaaattta tttctgtggg cgcatcgccg
    15121 ggaagagaat aacgtcgcga atagtatgac tgtttgtaaa cagcataatc attcggtcga
    15181 taccaatacc cagaccagcg gttggcggca gaccatattc cagcgcagtc acgtaatctt
    15241 cgtcatagaa catggcttcg tcgtcacctg cagctttagc gttaacctgt tcctggaaac
    15301 gttcagcctg atcttctgcg tcgtttaatt cgctaaaacc attaccgatt tcacgaccac
    15361 cgatgaagaa ttcaaaacgg tcggtgattt ccgggttaac atcattacgg cgcgccagcg
    15421 gtgacacttc tgccggatat tccgtaataa aggttggctg aatcagatgt gcttctgcca
    15481 cttcatcaaa gatctccgtg acaatacgtc ccagccccca gcttttctct accgtaattc
    15541 cgatagattc agctaatgct ttagcagcat caaaattatc caggtcggcc atatcggttt
    15601 ctggacgata ttttttgatt gcttcgcgca tggtgagttt ttcaaacggt ttgccgaaat
    15661 caaacacatg ctcgccataa gtgactttag tggtacccag aacctcttgt gccagggtgc
    15721 ggaacaggga ctctgtcagt tcaatcaaat cgtggtaatc cgcatacgcc atgtagagtt
    15781 ccatcattgt gaactcagga ttatggcgaa cagaaatacc ttcattacgg aagttacggt
    15841 tgatttcgaa tacccgttca aaaccgccta caaccagacg tttcagatac agctccggcg
    15901 cgatacgcag gtacatatct aaatccagag cgttatgatg ggtaataaac gggcgagcag
    15961 atgccccacc tggaattacc tgcatcatcg gggtttctac ttccataaag ccgcgcgcga
    16021 ccatgaactg gcggatagcg gccagaattt ttgaacggac aacaaacgtt tgacgggatt
    16081 tatcgttagc gatgaggtcc agataacgtt gacgataacg gacttcctga tcctgcagac
    16141 catggaattt atctggtaaa ggacgtagtg cttttgtcag caggcgcaac tcagtacagt
    16201 gaatggaaag ctcaccggtt tgcgtcttaa acagcgtacc gcgggcaccg ataatgtcac
    16261 ccagatccca ttttttaaac tgatcgttat aaacaccttc tggcaggcta tctcttgcaa
    16321 cgtacagttg aatacggcca ccgacatcct gcaacgttac aaaggaggct ttccccatga
    16381 tacgacgggt catcattcgg ccagcaaccg agacttcaat gtttaaggat tccagttcct
    16441 ggttatcctt cgcatcaaac tcttcgtgca actggtcaga ggtatggtcg cggcgaaaat
    16501 cattgggaaa cgccacacct tgctgacgta gtgccgccag tttttcgcgg cgatttctca
    16561 gttcatcgtt aaaatcaata gcctcattgg ctccccgtgt ttcttgttca gacattttgg
    16621 ttcctctaaa tccagctttc aatttagcgt agataaagag acagatcggt acactgtatt
    16681 atctgcctcg actattagta actcagttta tcttatcgaa actaacgctt acctcaagtt
    16741 gatatcacta ataaataacc atcaaaatgg tttaaatgac ttattaatct cgatttgtta
    16801 gtgttataaa ctgaaagtta atttattcat aaccaattgt ttttacgaca gttaatcgtt
    16861 gctctcctgt atcatattcg tcggcgtgct aaacagaaaa cgggtagcaa aggccaatac
    16921 gacgatgatc gcgacacaag ccaacgtcca ctctcccatc tgagaaaaga atcgctggta
    16981 agctgcaatt gccataccgc taatttgcga ctctgtcgtc tgctgtgcca cgacgcctgc
    17041 cagccagttg gcgaccgcgc ctgttgccag catataaatc ccggttaata cgccagacat
    17101 tttcagacgc gtgatttgcg caatcgccac cgggtcaata aagagttcgg caaagcccat
    17161 tagcgccagc ccggatatca tcacgcccat tgacgcttga ccgtcagccg ctgcatgtcg
    17221 ggcatcaaat gccaacaaca taaagccaca agccatcagc agtaagccaa aggcaaactt
    17281 cagccagacg cgcaatgttg agttgccgcg gctttctggc gacgccagcc aggccagtac
    17341 aaccccagcg agcatcaccg caattgcatt caccgactgg aatagtgctg taggtacttc
    17401 aatattgaat gcctgacgat tcacaaagcg atcgataaac aagctgatgg tactgccgcc
    17461 ctgttgtgcc agtacccaga acaatgtccc gacaaacatc aacaatacaa tttgccaaag
    17521 agcacggcga tgttcgggga atttgatcat catgcgggca atgatttgtg cggcaatgag
    17581 gcaaacgatc gccagcaaat atcccgacca gtcgttctcc agcagcaggg taaaaaatac
    17641 tggggctaaa cagagcatca ccactaacca gctccatact ggtaaggcaa atttcacgct
    17701 agtgagcgct tttttatcca tactacgcgt ggactggaaa tgacgatgcc cgcttaagaa
    17761 aatcaacaaa ccgataaaca tgccgccacc cgcaagggca aagccaacat gccatccata
    17821 ccactgagca gccaggccgc aggcgattgg ggcggcgata gaaccgatat tgcctgcagc
    17881 atacagcagc gaaaaaccgc catcacgtcg atgatcgttc tcgtcgtaga gctcgccaag
    17941 caaacagctg atgtttgatt tgaataaacc gtagccacaa ataatgattg ccagcgccag
    18001 atacaggcta aaggttgaat ttgtatcaat gcccagcacc acatggccaa gggtcattaa
    18061 cagcgcgccg gcaatcactg cagtgcggtt gccgagcagg cggtcggcaa gccagccgcc
    18121 gagaataggg gtaacgtaaa ccagagaagc atatgcgctg aacaggctga tggcatggtt
    18181 atcatcaaaa ccaagctgat gggtgagata gagaatgagt aaggcacgca tgccgtaaaa
    18241 actgaagtac tcccagattt ggatcgccac gatatagtat atcgcgcgcg gctgtgaggg
    18301 tgttttcatg tgttctcctt atgagcaaaa aagggaagtg gcaagccact tcccttgtac
    18361 gagctaatta ttttttgctt tcttctttca ataccttaac ggtatagcgg ccatcagcct
    18421 gacggtatgc accgtgaata tcggtttcaa agcccggata gtgagcgccg atttcacaca
    18481 gcatctgcag gaactccaga accggacggc tttcttcggt gatcatttca cccggcatta
    18541 ccagaggaac tcccggcgga tacggaagga tcatattggc gttaatacga cctaccattt
    18601 cgtcgaggta aacttcttcg gtcataccgt gcagctcttt ctggaatgca gcatacggag
    18661 tcattaccat cgtcggcagc acttcaaatg cgcggtacat cagatccggc agattgtggt
    18721 gaacaatcag tttgtggata ttctgagcca gttcctgaat acgcatgttt tcatagaatt
    18781 caggatcttc acgatacaga gacggcagca tgtttttcac acgcaggttc aggtcgaacg
    18841 cacgtttgaa gtcagtcaga gcacgcagca ggctcagtgc tttggtctta tcgataccga
    18901 tgctgaacag gaacagcagg ttatacggac cggttttctc aacaacgatg ccatgttcgt
    18961 cgaggtattt cgccacgatg ctggccggaa taccaaagtc gctcatggtg ccgtcttttt
    19021 ccatccccgg agtcagcagg gtgactttga tcgggtcaag atacatgtgc tcgttatcga
    19081 tgtttttgaa gccgtgccag gtgctgtcag aacgcagcgg ccagcattca gtcgtatcga
    19141 tatgatccgg ctgccataca tcaaagaacc agccatcaga ttccgttctc agacgtttga
    19201 tctctttacg gaatttgatc gcacgttcaa tggaaccgtt gatcagacgt ttacctgcat
    19261 tgcctttcat catcgccgca gcggtttcag tggacgccac gataccgtag tgcggagaag
    19321 tggtggtgtg catcatgtag gcttcgttaa aggtttcttc gtttacgtca cctttaacgt
    19381 ggatcatgga agcctgagag aacgccgcca gcagtttgtg agtggactgg gtttcgtaaa
    19441 tcactttccc ttctacacgg ccaccgctca taccgcattt accttcgtaa atcggtgaga
    19501 agttggtgta aggcacccac gcggagtcaa agtggatgga tttcacatcc agtgttttct
    19561 tgatgaagtc ggtgttgtac agcagaccat cataggtaga gttggtaatt acagcatgta
    19621 ccggccaggt tgcgtttggt gtttctttca cgcgcttagc aatggtagcg tgctggaatt
    19681 cactctgtgg gataccacca agaataccgt aagcgttacg ggtcgggcgg aaatagattg
    19741 gcgtaacatc gctcatcatc atcaggtggg tcagcgattt gtggcagtta cggtcaatca
    19801 gaatggtgct gcctgccgga gcagagtaca tgccaacaat tttgttcgca gtggaagtac
    19861 cgttggtcac catgtagctg cggtctgcgt taaagacgcg agcgatatac tgttctgctt
    19921 ctttgtgtgg accactgtga tccagcagag aacccagttc agatactgaa atggaaatat
    19981 cagatttcat ggtattcgga ccaaagaaat catagaacag gctacctacc gggcttttct
    20041 ggaatgcagt accgcccatg tgaccaggag tacagaaagt atatttacct tcacgaacat
    20101 atttaaacag tgctttagtc agcggaggca gaatagtgtt gatatattcg tcagtggtct
    20161 gcttgatctt attagcaata tcttcagcag cacccagcgc atattcaaag aagctaatct
    20221 gtaaacgcag gtcattcagg cttacatcga gagtggaata cgtattagcg aacgcgtaca
    20281 acggcaggtt ctcgttcatt ttgctaattt cttcgcacag ctcgagatta tatttatccc
    20341 agtcaaaaat aacgccgcac agacgcgcat tgttttcgat cagttttaat aagtcgtcac
    20401 ggtcgttcgg gtaaacaatc tggaagttca gacgttcaag cgcgcgatga agttcacgga
    20461 tgggttcttc tttaaaataa acccccatgt gattcaatat tgcaataacg ttcatagtca
    20521 tatctccagg taaaaaaggc ccctcccaac acatgggaca aaatgaaagg aggagcctcg
    20581 gaaaatactt ttaattaatg tgcgttagac gcggtgtggt tatccattga gtggctctgg
    20641 cgctcgtgca ttttgcgagc gtagaacatc aggataatca ggctgacgat gaaggtacct
    20701 gccagctcga aggagcttgc gcccatcagc gcgatgaagc agaacacgca acccagtaca
    20761 gagcagatca ggctgacaaa gttgcggatg ttaacgcctt caaaacgaat caggtcaacg
    20821 caagagtaga agtacggcag catagtcagc agtactgcga taccggtcag ttcaccgaac
    20881 aggtcagatg ctttaccacc ggcagagttc atcagagtga tgaggatcat cagggcagtc
    20941 attttcactg cagccagcag cagacctttt ttcggaatac cgttgctgtc gacttcacca
    21001 taaactttcg ggaagttacc gtcgttagcg gcacgtacac ctgcctggcc taccaacatc
    21061 atccaggagc ccagagaagt caggcacgca aaggcggtga atgcagaaac cagcggcgca
    21121 gcccagttac cgaggatggt tgaagcactg attgcaaacg gagcaccgga agctgccatt
    21181 acagaagatg gatacatacc ggaaagcacc tgagtcgcag cgatgtaaac aatacctgct
    21241 aaaccagtac ccagcatggt tgccagcgga acggtacgtt tcgggttttt aaccatacca
    21301 gtacttactg ctgcggattc aacacccacg aaggcccaca ggcagagcag aatactttta
    21361 atgatcgcat gaccatcagt ggtatccgca gtattccagt tagctgcata agttgccgca
    21421 tcaaaccaat gccagccaac aatagcagtc atcaccacag gaataagaac cagcaccaga
    21481 ccaatagtgg ttaaacggct tacccaagta ccgccgagca tatttacaaa ggtaaatacc
    21541 cagacgatag caatacaggc gatacccgcc ggaacaggat catttaatac tgggaagaag
    21601 gtggaaagat aagataccgc ggtaatacca atcgccaggt taccaatcca gttagcatgg
    21661 taataaagaa cacctgtctg aaaaccaaat gcaggggaaa tttctccggc ataagcaatt
    21721 gggccacctt gttgcgggtt ttttgttgcc agtcgggcat atacatacgc cagcgacatt
    21781 gcaccaataa tagagataat ccaaccccag atagcaatac caccgatact tgctaggttc
    21841 gcaggtaata atgcaatacc gctccccatc atattaccgg caacaacacc ggtacaggca
    21901 aatagcccga tcttcttggc agaactcatg ctcttctcct aatttcattt ttgaatttgg
    21961 agtccgggtc atgatgtata actatttcct gaccagacca aactggcgct aagaatactc
    22021 acgaaaaaag gattaatcct aaagattagg tgaaataata caaaagtttc tgtaagtgag
    22081 aacttgaggt tttttattaa cacatcagga tcgcaagttg atatcatgaa aagataaaca
    22141 ttcaatgttt acaatgg
//
LOCUS       DAPGUL010000074        22088 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.075, whole genome shotgun sequence.
ACCESSION   DAPGUL010000074 DAPGUL010000000
VERSION     DAPGUL010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22088
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.075"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(358..1278)
                     /gene="malM"
                     /locus_tag="RHX21_003003"
     CDS             complement(358..1278)
                     /gene="malM"
                     /locus_tag="RHX21_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose operon protein MalM"
                     /protein_id="HDV1988156.1"
                     /translation="MKMNKSLIALCLSAGLLASAPGISLADVNYVPQNTSDAPAIPSA
                     ALQQLTWTPVDQSKTQTTQLATGGQQLNVPGISGPVAAYSVPANIGELTLTLTSEVNK
                     QTSVFAPNVLILDQNMTPSAFFPSSYFTYQEPGVMSADRLEGVMRLTPALGQQKLYVL
                     VFTTEKDLQQTTQLLDPAKAYAKGVGNSIPDIPDPVARHTTDGLLKLKVKTNSSSSVL
                     VGPLFGSSAPAPVTVGNTAAPAVAAPAPAPVKKSEPMLNDTESYFNTAIKNAVAKGDV
                     DKALKLLDEAERLGSTSARSTFISSVKGKG"
     gene            complement(1521..2861)
                     /gene="lamB"
                     /locus_tag="RHX21_003004"
     CDS             complement(1521..2861)
                     /gene="lamB"
                     /locus_tag="RHX21_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltoporin LamB"
                     /protein_id="HDV1988157.1"
                     /translation="MMITLRKLPLAVAVAAGVMSAQAMAVDFHGYARSGIGWTGSGGE
                     QQCFQTTGAQSKYRLGNECETYAELKLGQEVWKEGDKSFYFDTNVAYSVAQQNDWEAT
                     DPAFREANVQGKNLIEWLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDVG
                     FGKLSLAATRSSEAGGSSSFASNNIYDYTNETANDVFDVRLAQMEINPGGTLELGVDY
                     GRANLRDNYRLVDGASKDGWLFTAEHTQSVLKGFNKFVVQYATDSMTSQGKGLSQGSG
                     VAFDNEKFAYNINNNGHMLRILDHGAISMGDNWDMMYVGMYQDINWDNDNGTKWWTVG
                     IRPMYKWTPIMSTVMEIGYDNVESQRTGDKNNQYKITLAQQWQAGDSIWSRPAIRVFA
                     TYAKWDEKWGYDYNGDSKVNPNYGKAVPADFNGGSFGRGDSDEWTFGAQMEIWW"
     gene            complement(2933..4048)
                     /gene="malK"
                     /locus_tag="RHX21_003005"
     CDS             complement(2933..4048)
                     /gene="malK"
                     /locus_tag="RHX21_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011915502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose/maltodextrin ABC transporter ATP-binding
                     protein MalK"
                     /protein_id="HDV1988158.1"
                     /translation="MASVQLQNVTKAWGEVVVSKDINLDIHEGEFVVFVGPSGCGKST
                     LLRMIAGLETITSGDLFIGEKRMNDTPPAERGVGMVFQSYALYPHLSVAENMSFGLKL
                     AGAKKEVINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEP
                     LSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKP
                     LELYHYPADRFVAGFIGSPKMNFLPVKVTATAIDQVQVELPMPNRQQVWLPVESRDVQ
                     VGANMSLGIRPEHLLPSDIADVILEGEVQVVEQLGNETQIHIQIPSIRQNLVYRQNDV
                     VLVEEGATFAIGLPPERCHLFREDGTACRRLHKEPGV"
     gene            4413..5603
                     /gene="malE"
                     /locus_tag="RHX21_003006"
     CDS             4413..5603
                     /gene="malE"
                     /locus_tag="RHX21_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose/maltodextrin ABC transporter
                     substrate-binding protein MalE"
                     /protein_id="HDV1988159.1"
                     /translation="MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYN
                     GLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLL
                     AEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPA
                     LDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGL
                     TFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTF
                     KGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYE
                     EELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQT
                     RITK"
     gene            5757..7301
                     /gene="malF"
                     /locus_tag="RHX21_003007"
     CDS             5757..7301
                     /gene="malF"
                     /locus_tag="RHX21_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose ABC transporter permease MalF"
                     /protein_id="HDV1988160.1"
                     /translation="MDVIKKKHWWQSDALKWSVLGLLGLLVGYLVVLMYAQGEYLFAI
                     TTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVLFPLVCTIAIAFTNYSSTNQLTF
                     ERAQEVLLDRSWQAGKTYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLK
                     ETTAQPEGERANLRVITQNRQALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGNGT
                     LTNNQSGVKYRPNNQIGFYQSITADGNWGDEKLSPGYTVTTGWKNFTRVFTDEGIQKP
                     FLAIFVWTVVFSLITVFLTVAVGMVLACLVQWEALRGKAVYRVLLILPYAVPSFISIL
                     IFKGLFNQSFGEINMMLSALFGVKPAWFSDPTTARTMLIIVNTWLGYPYMMILCMGLL
                     KAIPDDLYEASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNG
                     GPDRLGTTTPAGYTDLLVNYTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAIVNLKA
                     TRMKFD"
     gene            7316..8206
                     /gene="malG"
                     /locus_tag="RHX21_003008"
     CDS             7316..8206
                     /gene="malG"
                     /locus_tag="RHX21_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001252048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose ABC transporter permease MalG"
                     /protein_id="HDV1988161.1"
                     /translation="MAMVQPKSQKARLFITHLLLLLFIAAIMFPLLMVVAISLRQGNF
                     ATGSLIPEQISWDHWKLALGFSVEQADGRITPPPFPVLLWLWNSVKVAGISAIGIVAL
                     STTCAYAFARMRFPGKATLLKGMLIFQMFPAVLSLVALYALFDRLGEYIPFIGLNTHG
                     GVIFAYLGGIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVV
                     FILSFIAAITEVPVASLLLRDVNSYTLAVGMQQYLNPQNYLWGDFAAAAVMSALPITI
                     VFLLAQRWLVNGLTAGGVKG"
     gene            8578..10053
                     /gene="xylE"
                     /locus_tag="RHX21_003009"
     CDS             8578..10053
                     /gene="xylE"
                     /locus_tag="RHX21_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose transporter XylE"
                     /protein_id="HDV1988162.1"
                     /translation="MNTQYNSSYIFSITLVATLGGLLFGYDTAVISGTVESLNTVFVA
                     PQNLSESAANSLLGFCVASALIGCIIGGALGGYCSNRFGRRDSLKIAAVLFFISGVGS
                     AWPELGFTSINPDNTVPIYLAGYVPEFVIYRIIGGIGVGLASMLSPMYIAELAPAHIR
                     GKLVSFNQFAIIFGQLLVYCVNYFIARSGDASWLNTDGWRYMFASECIPALLFLMLLY
                     TVPESPRWLMSRGKQEQAESILRKIMGNTLATQAVQEIKHSLDHGRKTGGRLLMFGVG
                     VIVIGVMLSIFQQFVGINVVLYYAPEVFKTLGASTDIALLQTIIVGVINLTFTVLAIM
                     TVDKFGRKPLQIIGALGMAIGMFSLGTAFYTQASGIVALLSMLFYVAAFAMSWGPVCW
                     VLLSEIFPNAIRGKALAIAVAAQWLANYFVSWTFPMMDKNSWLVAHFHNGFSYWIYGC
                     MGVLAALFMWKFVPETKGKTLEELEALWEPETKKTQQTATL"
     gene            complement(10097..10507)
                     /gene="psiE"
                     /locus_tag="RHX21_003010"
     CDS             complement(10097..10507)
                     /gene="psiE"
                     /locus_tag="RHX21_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-starvation-inducible protein PsiE"
                     /protein_id="HDV1988163.1"
                     /translation="MTSLSRPRVEFISTILQTVLNLGLLCLGLILVVFLGKETVHLAD
                     VLFAPEQTSKYELVEGLVVYFLYFEFIALIVKYFQSGFHFPLRYFVYIGITAIVRLII
                     VDHKSPLDVLIYSAAILLLVITLWLCNSKRLKRE"
     gene            10722..11000
                     /locus_tag="RHX21_003011"
     CDS             10722..11000
                     /locus_tag="RHX21_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988164.1"
                     /translation="MKRNLIKVVKMKPYFAALMLSVSVLPAYAGPLGTADKADLPQSN
                     VSSPMMAQSLRQPDLQPISTDRKTECFRLYTPDRKPGVNCVPDGSTGH"
     gene            complement(11047..13143)
                     /locus_tag="RHX21_003012"
     CDS             complement(11047..13143)
                     /locus_tag="RHX21_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbH domain-containing protein"
                     /protein_id="HDV1988165.1"
                     /translation="MKKRHLLSLLALGISTACYGETYPAPIGPSQSDFGGVGLLQTPT
                     ARMAREGELSLNYRDNDQYRYYSASVQLFPWLETTLRYTDVRTRQYSSVEAFSGDQTY
                     KDKAFDLKLRLWEESYWLPQVAVGARDIGGTGLFDAEYLVASKAWGPFDFTLGLGWGY
                     LGTSGNVKNPLCSASDKYCYRDNSYKQAGSIDGSQMFHGPASLFGGVEYQTPWQPLRL
                     KLEYEGNNYQQDFAGKLEQKSKFNVGAIYRVTDWADVNLSYERGNTFMFGVTLRTNFN
                     DLRPSYNDNARPQYQPQPQDAILQHSVVANQLTLLKYNAGLADPQIQAKGDTLYVTGE
                     QVKYRDSREGIIRANRIVMNDLPDGIKTIRITENRLNMPQVTTETDVASLKNHLAGEP
                     LGHETKLAQKRVEPVVPQSTEQGWYIDKSRFDFHIDPVLNQSVGGPENFYMYQLGVMG
                     TADLWLTDHLLTTGSLFANLANNYDKFNYTNPPQDSHLPRVRTHVREYVQNDVYVNNL
                     QANYFQHLGNGFYGQVYGGYLETMFGGAGAEVLYRPLDSNWAFGLDANYVKQRDWRSA
                     KDMMKFTDYSVKTGHLTAYWTPSFAQDVLVKASVGQYLAGDKGGTLEIAKRFDSGVVV
                     GGYATITNVSKEEYGEGDFTKGVYVSVPLDLFSSGPTRSRAAIGWTPLTRDGGQQLGR
                     KFQLYDMTSDRSVNFR"
     gene            complement(13143..13880)
                     /locus_tag="RHX21_003013"
     CDS             complement(13143..13880)
                     /locus_tag="RHX21_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule biosynthesis GfcC family protein"
                     /protein_id="HDV1988166.1"
                     /translation="MIKQTIVALILSVGASSVFAAGTVKVFSNGSSEAKTLTGAEYLI
                     DLVGQPRLANSWWPGAVISEELATAAALRQQQALLTRLAELAADSSADDAAAINALRQ
                     QIQALKVTGRQKINLDPDIVRVAERGNPPLQGNYTLWVGPPPSTVTLFGLISRPGKQP
                     FTPGRDVASYLSGQNLLSGADRSYAWVVYPDGRTQKAPVAYWNKRHVEPMPGSIIYVG
                     LADSVWSETPDALNADILQTLTQRIPQ"
     gene            complement(13877..14515)
                     /locus_tag="RHX21_003014"
     CDS             complement(13877..14515)
                     /locus_tag="RHX21_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418451.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbF family lipoprotein"
                     /protein_id="HDV1988167.1"
                     /translation="MKRPALILICLLLQACSATTKELGNSLWDSLFGTPGVQLTDDDI
                     QNMPYASQYMQLNGGPQLFVVLAFAEDGQQKWVTQDQATLVTQHGRLVKTLLGGDNLI
                     EVNNLAADPLIKPAQIVDGATWTRTMGWTEYQQVRYATARSVFKWDGTDTVKVGSDET
                     PVRVLDEEVSTDQARWHNRYWIDSEGQIRQSEQYLGADYFPVKTTLIKAAKQ"
     gene            complement(14629..14871)
                     /locus_tag="RHX21_003015"
     CDS             complement(14629..14871)
                     /locus_tag="RHX21_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988168.1"
                     /translation="MKKVLYGIFAISALAATSAWAAPVQVGEAAGSAATSVSAGSSSA
                     TSVSTVSSAVGVALAATGGGDGSNTGTTTTTTTSTQ"
     gene            complement(15226..16875)
                     /gene="pgi"
                     /locus_tag="RHX21_003016"
     CDS             complement(15226..16875)
                     /gene="pgi"
                     /locus_tag="RHX21_003016"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HDV1988169.1"
                     /translation="MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSAT
                     FGDQMLVDYSKNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALR
                     NRSNTPILVDGKDVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDL
                     GPYMVTEALRPYKNHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTN
                     AHSARDWFLKAAGDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSA
                     IGLSIVLSIGFDNFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEA
                     ILPYDQYMHRFAAYFQQGNMESNGKYVDRNGNVVDYQTGPIIWGEPGTNGQHAFYQLI
                     HQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKD
                     PATLDYVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQW
                     GVELGKQLANRILPELKDDKEISSHDSSTNGLINRYKAWRG"
     gene            17400..18749
                     /gene="lysC"
                     /locus_tag="RHX21_003017"
     CDS             17400..18749
                     /gene="lysC"
                     /locus_tag="RHX21_003017"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine-sensitive aspartokinase 3"
                     /protein_id="HDV1988170.1"
                     /translation="MSEIVVSKFGGTSVADFDAMNRSADIVLSDANVRLVVLSASAGI
                     TNLLVALAEGLEPGERFEKLDAIRNIQFAILERLRYPNVIREEIERLLENITVLAEAA
                     ALATSPALTDELVSHGELMSTLLFVEILRERDVQAQWFDVRKVMRTNDRFGRAEPDVA
                     ALAELAALQLLPRLNDGLVITQGFIGSENKGRTTTLGRGGSDYTAALLAEALHASRVD
                     IWTDVPGIYTTDPRVVSAAKRIDEIAFAEAAEMATFGAKVLHPATLLPAVRSDIPVFV
                     GSSKDPRAGGTLVCNKTENPPLFRALALRRNQTLLTLHSLNMLHSRGFLAEVFGILAR
                     HNISVDLITTSEVSVALTLDTTGSTSTGDTLLTQSLLMELSALCRVEVEEGLALVALI
                     GNDLSKACGVGKEVFGVLEPFNIRMICYGASSHNLCFLVPGEDAEQVVQKLHFNLFE"
     gene            18894..19820
                     /locus_tag="RHX21_003018"
     CDS             18894..19820
                     /locus_tag="RHX21_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001666873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HDV1988171.1"
                     /translation="MATLMEKDALLNGASQCIAFLSNIIDNCSVSSHQDSGDALKRLV
                     SYRDYLYSTPAELVDFTQGKILLQQVRTQYQHEFNNTTHSENKASFDSIWQRLTNHEV
                     TPQQHPIGFVLGGQPGAGKSSLIELAKRETKDNIMIINGDDFRFLHPDFNYIYQNYGD
                     DFVTHTAKFSGETVERAIERAIVSKLNIVVEGTFRNAATPLQTLKKLKDAGYQTEVMI
                     KTTSAALSWESTNERYSKDKEAGNIARKVDKNHHDIVTGLLAENARKVFASNLSDKFA
                     VYSREKMIFSSQAATNDDIATLIQNEISGNTQ"
     gene            complement(19856..20647)
                     /locus_tag="RHX21_003019"
     CDS             complement(19856..20647)
                     /locus_tag="RHX21_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HDV1988172.1"
                     /translation="MPLNGVSAAMRERVSQQLREIERRYDVKVLYACESGSRGWGFAS
                     PDSDYDVRFLYVHPLEWYLRVEAPRDVIELPIDDELDVSGWEWRKALGLLKGANPTLI
                     EWLDSPVVYQQDEETITALKAMVPKWFSPLRARWHYYSMARKNFRGYLQGDEVRLKKY
                     FYVLRPLLAVRWVEAGKGVPPMRFAELLAGSELDAPLRAEIDELLERKQRAGEAEYGP
                     RRPLLHAFIRAELARGEIPPLLPDSREGDVKELDSLMYQTVMRRA"
     gene            complement(20653..21780)
                     /locus_tag="RHX21_003020"
     CDS             complement(20653..21780)
                     /locus_tag="RHX21_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="slipin family protein"
                     /protein_id="HDV1988173.1"
                     /translation="MIKKISVRKDQLALLSRNGDYYKVLHAGEHLLPWLNTPEVLLIT
                     LDGSEVPDVLADYLRRFQPDWVEKYCLVADLSEIEAGALYMDGILQEILPPSTRRLYW
                     RVEDDLTLVRMNTQQVQVQTEVMNAVLQPRRKGAVKGRDAILTVQVPAWHVGVLKIDG
                     ETQALLPPGLTAYWKINHLVDAEVVDTRLQVLEVSGQEILTKDKVNLRINLAANWRYS
                     DVLLAFSQLTKPIDHLYRELQFALREAVGTRTLDELLEDKQVIDDVVSEQVKSRMLPF
                     GMEIASLGVKDIVLPGDMKNILAQLVEAEKSAQANVIRRREETAATRSLLNTAKVMEN
                     NPVALRLKELETLERVAERIDNISVFGGLDQVLHGLVNIKG"
BASE COUNT         5272 a         5759 c         5527 g         5530 t
ORIGIN      
        1 atctctgttt aaacctggca ccccattgaa attacgtagt aaatcaagat ctactatatt
       61 atttccttgc accacatcat gtttcatcaa agagttattg ccgccagaat ttaggatatg
      121 acttatcata aaacctctgc ataacagaaa taaaataacc tggaaaagta gcctgaatgt
      181 ccagacacta ccggcgaaag gaaaagaatc tctgataagg cattgagata atggatattc
      241 ttagtgaaga agaagtgagt tactataaaa aatcgctcat atcccaggaa ggaagcataa
      301 aaaaaggtgc gccaggagac gcaccagttg ttgcaaaatc agcactgtgg ggcgtaatta
      361 ccccttgcct tttacactgc tgataaaggt ggaacgggca gatgtcgatc ccaggcgttc
      421 agcttcatca agcagtttta acgccttatc aacatcacct ttcgcgacag cgtttttgat
      481 cgcggtatta aaataacttt ccgtgtcgtt gagcatcggc tcgcttttct tcaccggtgc
      541 cggagcgggt gcagccacag ctggtgccgc cgtgttacct accgtaaccg gagctggagc
      601 ggaagaacca aataaaggtc ctaccaacac gctggagctg gagttcgttt tcactttcag
      661 tttcagtaag ccatcggtgg tatgacgagc aaccggatcg gggatatccg ggatcgagtt
      721 accgacgccc ttggcatagg ctttagccgg gtcgagcagt tgggtcgtct gctggagatc
      781 tttttccgtg gtaaagacca gaacataaag tttttgctgc cccaacgccg gtgtcaggcg
      841 cataacgcct tccagccgat ctgcactcat cacgcctggt tcctggtagg tgaaataact
      901 gctggggaag aaggctgatg gggtcatgtt ctgatcaaga atcagcacgt tcggcgcaaa
      961 aacgctggtt tgtttgttca cttcgctggt cagcgtcagg gtcagttcgc caatgtttgc
     1021 cgggacgctg tacgcagcaa ccggaccact gatgccggga acgttcagtt gttggccgcc
     1081 ggtcgccagt tgggtggtct gggttttaga ttgatcgacc ggtgtccagg tgagttgttg
     1141 cagcgcggca gatggaatgg ctggcgcgtc gctggtgttt tgcggtacgt agttaacatc
     1201 ggcaaggctg attccaggcg cgcttgccag taaccctgct gataaacaga gggcgatgag
     1261 acttttattc attttcattg ttttcacctc aaaatctgga gctcagcggt agccaggcaa
     1321 tagcgcgcta aacccgataa tcagaggggc tttcgcccct ttcagataat gacaacctgt
     1381 ttttatgccg gatgcggcgt aaacgcctta tccggcctac atttgacagc cgttgtaggc
     1441 ctgataagac gcgcaagcgt cgcatcaggc gttggttgtc gaatgcggcg taaacgcctt
     1501 atccggccca ggttttgcta ttaccaccag atttccatct gggcaccgaa ggtccactcg
     1561 tcgctgtcgc cacgaccgaa gctgccgccg ttgaaatcag caggaacggc tttgccgtag
     1621 ttcgggttaa ccttgctatc gccgttgtag tcataacccc atttctcatc ccacttggcg
     1681 taggttgcga agacacgaat agccgggcgt gaccagatgc tgtcgccagc ctgccattgt
     1741 tgtgcgaggg taattttgta ctgattgttc ttgtcgccgg tgcgctggga ttcgacgttg
     1801 tcgtagccga tttccatcac ggtgctcatg attggcgtcc acttgtacat cgggcgaata
     1861 ccaacggtcc accacttggt gccgttgtcg ttatcccagt tgatatcctg gtacataccc
     1921 acgtacatca tgtcccagtt gtcgcccatg gagatcgcac cgtggtcgag gatacgcagc
     1981 atgtgaccgt tgttgttgat attgtaggca aatttttcgt tatcaaacgc gacgccagaa
     2041 ccctgcgaca gacctttacc ctgcgaggtc atcgagtcag tagcgtactg aacaacaaac
     2101 ttgttaaagc ccttcaggac actctgagta tgttcagcag tgaataacca gccgtctttc
     2161 gatgcgccat caaccagacg atagttatca cgcaggttgg cacgaccgta gtcgacaccc
     2221 agttctaatg tgccgcccgg gttgatttcc atctgcgcta aacgcacatc gaaaacgtcg
     2281 ttcgcggttt cgttggtata gtcataaata ttgttgctgg caaaagagga agaaccacca
     2341 gcttcagagg agcgggttgc tgccagagag agtttaccga agccaacatc gatgttttcc
     2401 agaccggcac caggaccaga aatatcccag tagtagaagt cgatcatatg aacgtcatga
     2461 cgttggtaga agcgcttacc tgcccagatg gtggaacctg gcagccattc gatcaggttt
     2521 ttaccctgca cgtttgcttc acggaaggcc ggatcggtag cttcccagtc attctgttgc
     2581 gcgacggaat aggccacgtt agtgtcgaaa tagaagctct tatcgccctc tttccacact
     2641 tcctgaccca attttaattc agcataagtt tcacattcgt tgccaagacg gtatttactt
     2701 tgagcaccgg tagtctggaa acactgttgt tcaccgccgc tacctgtcca gccaataccg
     2761 gaacgtgcat agccgtggaa atcaacagcc attgcctgag cagacattac gcccgctgcg
     2821 acggcaaccg ccagaggaag tttgcgcaga gtaatcatca ttctatctcc tgagtcattg
     2881 cttttctttt ttcacatcac ctgtgacagg ctttgtgtgt tttgtggggt gcttaaacgc
     2941 ccggctcctt atgcagtcga cgacatgcag tgccatcctc acggaacaga tggcaacgct
     3001 ctggcggcag gccgatagcg aatgtggcac cttcttctac caacaccacg tcgttctggc
     3061 ggtacaccag gttttgacga atggaaggga tctggatatg gatttgggtt tcgttgccga
     3121 gttgctcgac gacctgaact tcaccctcaa ggatgacgtc agcgatatca ctcggcagta
     3181 gatgttccgg gcgaataccc agcgacatat tggctccaac ctggacatca cggctttcaa
     3241 ctggcagcca gacttgctga cgatttggca tcggcagctc cacctgcact tgatcgattg
     3301 cggtggcggt cacttttacc ggcaggaagt tcatctttgg cgaaccgata aatccggcga
     3361 caaaacggtc tgccggatag tggtacagct ccagcggttt cccaacctgc gccacgcgac
     3421 cggcgtccag caccacgatt ttgtcggcca gcgtcatcgc ttcgacctga tcgtgggtga
     3481 cgtaaatcat tgtgcggccc aggcgtttat gcagacggga gatttcgata cgcatttgca
     3541 cacgcagtgc agcatcgagg ttggagagcg gttcatcgag caaaaatacg cttggctcgg
     3601 ccaccagcgt acggccaatc gccacacgct gacgctgacc gccagagagc gctttcggtt
     3661 tgcgatccag caaatgcgcc agttgcagca cttccgccac ctggttaacg cgttggttaa
     3721 tcacctcttt ttttgcgcct gccagtttca ggccaaatga catattttct gctactgaca
     3781 ggtggggata gagcgcgtaa gactgaaaca ccataccaac gccgcgttct gctggcggag
     3841 tgtcattcat ccgtttctca ccgatgaaca ggtcgccgct ggtgatcgtc tcaagcccgg
     3901 caatcatgcg cagtaaagtc gatttaccgc agccagacgg tccgacaaac accacgaatt
     3961 cgccttcatg gatatcgaga ttgatatctt tcgataccac gacctcgccc caggctttcg
     4021 ttacattttg cagctgtacg ctcgccatgc ccttctccct ttgtaacaac ctgtcatcga
     4081 cagcaacatt catgatgggc tgactatgcg tcatcaggag atggcttaaa tcctccaccc
     4141 cctggctttt ttatggggga ggaggcggga ggatgagaac acggcttctg tgaactaaac
     4201 cgaggtcatg taaggaattt cgtgatgttg cttgcaaaaa tcgtggcgat tttatgtgcg
     4261 catctccaca ttaccgccaa ttctgtaaca gagatcacac aaagcaacgg tggggcgtag
     4321 gggcaaggag gatggaaaga ggttgccgta taaagaaact agagtccgtt taggtgtttt
     4381 cacgagcact tcaccaacaa ggaccataga ttatgaaaat aaaaacaggt gcacgcatcc
     4441 tcgcattatc cgcattaacg acgatgatgt tttccgcctc ggctctcgcc aaaatcgaag
     4501 aaggtaaact ggtaatctgg attaacggcg ataaaggcta taacggtctc gctgaagtcg
     4561 gtaagaaatt cgagaaagat accggaatta aagtcaccgt tgagcatccg gataaactgg
     4621 aagagaaatt ccctcaggtt gcggcaactg gcgatggccc tgacattatc ttctgggcgc
     4681 acgaccgttt tggtggctac gctcaatctg gcctgttggc tgaaatcacc ccggacaaag
     4741 cgttccagga caagctgtat ccgtttacct gggatgccgt acgttacaac ggcaagctga
     4801 ttgcttaccc gatcgctgtt gaagcgttat cgctgattta taacaaagat ctgctgccga
     4861 acccgccaaa aacctgggaa gagatcccgg cgctggataa agaactgaaa gcgaaaggta
     4921 agagcgcgct gatgttcaac ctgcaagaac cgtacttcac ctggccgctg attgctgctg
     4981 acgggggtta tgcgttcaag tatgaaaacg gcaagtacga cattaaagac gtgggcgtgg
     5041 ataacgctgg cgcgaaagcg ggtctgacct tcctggttga cctgattaaa aacaaacaca
     5101 tgaatgcaga caccgattac tccatcgcag aagctgcctt taataaaggc gaaacagcga
     5161 tgaccatcaa cggcccgtgg gcatggtcca acatcgacac cagcaaagtg aattatggtg
     5221 taacggtact gccgaccttc aagggtcaac catctaaacc gttcgttggc gtgctgagcg
     5281 ccggtattaa cgccgccagt ccgaacaaag agctggcgaa agagttcctc gaaaactatc
     5341 tgctgactga cgaaggtctg gaagcggtta ataaagacaa accgctgggt gccgtagcgc
     5401 tgaagtctta cgaggaagag ttggcgaaag atccacgtat tgccgccacc atggaaaacg
     5461 cccagaaagg tgaaatcatg ccgaacatcc cgcagatgtc cgctttctgg tatgccgtgc
     5521 gtactgcggt gatcaacgcc gccagtggtc gtcagactgt cgatgaagcc ctgaaagacg
     5581 cgcagactcg tatcaccaag taatgctgtg aaatgccgga tgcggcgtga acgccttgtc
     5641 cggcctacaa aactgaaacg catgtaggcc tgataagacg catcagtgtc gcatcaggca
     5701 gttgttgtcg gataaggcgt gaaagcctta tccgtcctgg aatgaggaag aaccccatgg
     5761 atgtcattaa aaagaaacat tggtggcaaa gcgacgcgct gaaatggtca gtgctaggtc
     5821 tgctcggcct gctggtgggt taccttgttg ttttaatgta cgcacaaggg gaatacctgt
     5881 tcgccattac cacgctgata ttgagttcag cggggctgta tattttcgcc aatcgtaaag
     5941 cctacgcctg gcgctatgtt tacccgggaa tggctggaat gggattattc gtcctcttcc
     6001 ctctggtctg caccatcgcc attgccttca ccaactacag cagcactaac cagctgactt
     6061 ttgaacgtgc gcaggaagtg ttgttagatc gctcctggca agcaggcaaa acctataact
     6121 ttggtcttta cccggcgggc gatgagtggc aactggcgct cagcgacggc gaaaccggca
     6181 aaaattacct ctccgacgcg tttaaatttg gcggcgagca aaaactgcaa ctgaaagaaa
     6241 cgaccgccca gcccgaaggc gaacgcgcga atctgcgcgt gattacccag aatcgtcagg
     6301 cgctgagtga cattaccgcc attctgccgg atggcaacaa agtgatgatg agctccctgc
     6361 gccagttttc tggcacgcag ccgctctaca cactcgacgg taacggcacg ttgacgaata
     6421 atcagagtgg cgtgaaatat cgtccgaata accaaattgg cttttaccag tccattaccg
     6481 ccgacggcaa ctggggggat gaaaagctaa gccccggtta caccgtgacc accggctgga
     6541 aaaactttac ccgcgtcttt accgacgaag gcattcagaa accgttcctc gccattttcg
     6601 tctggaccgt ggtgttttca ctgatcaccg tctttttaac ggtggcggtc ggcatggttc
     6661 tggcgtgtct ggtgcagtgg gaagcgttgc gtggcaaagc ggtatatcgc gtcctgctga
     6721 ttctgcccta cgcggtgcca tcattcattt caatcttgat tttcaaaggg ttgtttaacc
     6781 agagcttcgg tgaaatcaac atgatgttga gcgcgctgtt tggcgtgaag cccgcctggt
     6841 tcagcgatcc gaccactgcc cgaacgatgc tgattatcgt caatacctgg ctgggttatc
     6901 cgtacatgat gatcctctgc atgggcttgc tgaaagcgat tccggacgat ttgtatgaag
     6961 cctcagcaat ggatggcgca ggtccgttcc agaacttctt taagattacg ctgccgctgc
     7021 tgattaaacc gctgacgccg ctgatgatcg ccagcttcgc ctttaacttt aacaacttcg
     7081 tgctgattca gctgttaacc aacggcggcc cggatcgtct tggcacgacc acgccagccg
     7141 gttataccga cctgcttgtt aactacacct accgtatcgc ttttgaaggc ggcgggggtc
     7201 aggacttcgg tctggctgca gcaattgcca cgctgatctt cctgctggtg ggtgcgctgg
     7261 cgatagtgaa cctgaaagcc acgcgaatga agtttgatta agggagataa caaaaatggc
     7321 aatggtccaa ccgaaatcgc aaaaagcacg tttgtttatt actcacctgc tactgctact
     7381 ttttatcgcg gcgattatgt tcccgctgct gatggtcgtc gctatctcgc tgcgtcaggg
     7441 aaacttcgcg accggtagcc tgatcccgga gcaaatctcc tgggatcact ggaaactggc
     7501 gttaggtttt agcgttgaac aggctgatgg tcgcattacg ccaccgccat tcccggtact
     7561 gctgtggctg tggaactcgg taaaggtcgc cgggatttcc gcgattggca ttgtggcgct
     7621 ctccaccacc tgcgcctacg ctttcgcccg tatgcgcttt ccaggcaaag cgacgctgct
     7681 gaaaggaatg ctgattttcc agatgttccc ggcagtactt tcactggtcg cgttgtatgc
     7741 gttgtttgat cgtctgggtg agtacattcc attcattggc ctgaatactc acggcggcgt
     7801 aattttcgcg tatctgggtg ggattgcgct gcatgtctgg accatcaaag gctatttcga
     7861 aaccatcgac agttcgctgg aagaagcggc tgcgctggat ggtgcgacac cgtggcaggc
     7921 cttccgcctt gtcctgttgc cgctgtcagt accgattctg gcggtggtat tcatcctgtc
     7981 gtttatcgct gccattactg aagttccggt cgcgtcgctg ttactgcgtg acgtaaacag
     8041 ctacaccctg gccgtgggga tgcagcaata cctcaacccg caaaactacc tgtggggtga
     8101 ctttgccgcc gctgccgtga tgtctgcatt accgatcacc atcgtcttct tgctggctca
     8161 acgctggctg gtcaacggcc tgacggcagg tggtgtgaaa ggttaaagat gttgttctgc
     8221 caatgttatg ccgctgcacc ctcaacttac gttatcccaa cttgtgactg ttattcggcg
     8281 ctccacggag cgcctttttt tctttcgtct gcaatctgaa tcgttcgccg gttaatattc
     8341 ccatcataga gcttattatt tttacgttat ttgttttccc acttacgata attctctttc
     8401 gtgctctgag tcacggcaat agtattgttt tcatcaattt ttgataatta tcacaattaa
     8461 gatcacagaa aagacattac gtaaacgcat tgtaaaaaat gataattgcc ttaactgcct
     8521 gacaattcca acatcaatgc actgataaaa gatcagaatg gtctaaggca ggtctgaatg
     8581 aatacccagt ataattccag ttatatattt tcgattacct tagtcgctac attaggtggt
     8641 ttattatttg gctacgacac cgccgttatt tccggtactg ttgagtcact caataccgtc
     8701 tttgttgctc cacaaaactt aagtgaatcc gctgccaact ccctgttagg attttgcgta
     8761 gccagtgctc tgattggttg catcatcggc ggtgccctcg gtggttattg cagtaaccgc
     8821 ttcggccgtc gtgattcact taagattgct gctgtcctgt tttttatttc tggtgtaggt
     8881 tctgcctggc cagaacttgg ttttacctct ataaacccgg acaacacagt ccctatttat
     8941 ctggcaggtt atgtcccgga atttgttatt tatcgtatta ttggcggtat tggcgttggt
     9001 ttagcctcaa tgctttcacc aatgtatatt gcggaactgg ctccagctca tattcgcgga
     9061 aaactggttt catttaacca gtttgcgatt attttcgggc aacttttagt ttactgcgta
     9121 aactatttta ttgcccgttc cggtgatgcc agctggctga atactgacgg ctggcgttat
     9181 atgtttgcct cggaatgtat ccctgcactg ctgttcttaa tgctgctgta taccgtgcca
     9241 gaaagtcctc gctggctgat gtcacgcggc aagcaagaac aggcggaaag tatcctgcgc
     9301 aaaattatgg gcaacacgct tgcaactcag gcagtacagg aaattaaaca ctccctggat
     9361 catggccgca aaaccggtgg tcgtctgctg atgtttggcg tgggcgtgat tgtaatcggc
     9421 gttatgctct ccatcttcca gcaatttgtc ggcatcaatg tggtgctgta ctacgcgccg
     9481 gaagtgttca aaacgctggg ggccagcacg gatatcgcgc tgttgcagac cattattgtc
     9541 ggagttatca acctcacctt taccgtactg gcaattatga cggtggataa atttggtcgt
     9601 aagccactgc aaattatcgg cgcactcgga atggcaatcg gtatgtttag cctcggtacc
     9661 gcgttttaca ctcaggcatc gggtattgtg gcgctactgt cgatgctgtt ctatgttgcc
     9721 gcctttgcca tgtcctgggg tccggtatgc tgggtactgc tgtcggaaat cttcccgaat
     9781 gctattcgtg gtaaagcgct ggcaatcgcg gtggcggccc agtggctggc gaactacttc
     9841 gtctcctgga ccttcccgat gatggacaaa aactcctggc tggtggccca tttccacaac
     9901 ggtttctcct actggattta cgggtgtatg ggcgttctgg cagcactatt tatgtggaaa
     9961 tttgtcccgg aaaccaaagg taaaaccctt gaggagctgg aagccctctg ggaaccggaa
    10021 acgaagaaaa cacaacaaac tgctacgctg taatcttcct gtccagcacg ccgcgccagt
    10081 tcggcgtgct gtctttttac tcccgcttca gccgtttcga attacacagc cacagagtga
    10141 tcaccagtaa caggatcgca gccgagtaga tcaacacatc cagtggcgat ttatgatcga
    10201 cgatgatcaa gcgcacaatg gcggtgatcc caatatagac aaagtaacgt agcgggaagt
    10261 gaaaaccgga ctgaaagtat ttcacaatca gcgcgataaa ttcgaaatag agaaagtaaa
    10321 ccaccagtcc ttctaccagc tcatatttgc tggtttgttc tggcgcgaac agcacatctg
    10381 ccagatgcac cgtttctttg ccgaggaaga caaccaaaat caggccgagg cacaacaggc
    10441 caagattgag tacggtctgc aaaatggtgg agataaactc cacgcgcgga cgagagagtg
    10501 acgtcatagc agtacctcct tcacagtggc gagcttcctg tataacgcaa aaatgtgacg
    10561 gagatctata ttttttgtgt atgttttgtt cagcttgatt aagtgggcat ctcccatcaa
    10621 cgtcgcatct ggcaaaacac acagccccaa aaaatcaccc attcaggtga ttcccagcca
    10681 ccagcaatgc gcgaaaaatc gacaatgttc ctctggaaca aatgaaacgt aacctgataa
    10741 aggtggtaaa aatgaagcct tattttgctg ctttgatgtt atcagtctct gttcttcctg
    10801 cttatgctgg tccgctcggt actgctgata aagccgacct accgcaaagc aatgtctcca
    10861 gcccaatgat ggcccagtcg ctcaggcaac cagacctgca accgatatcg acggacagga
    10921 agacagaatg ttttcgcctt tacacaccag atcgtaaacc gggggtgaac tgcgttcctg
    10981 atggctcaac aggtcattaa gaatgagggt gccagtgagt gcgaaaactg gcacctttcc
    11041 catgacttag cggaaattta cgctacggtc gctggtcata tcatacaact ggaacttacg
    11101 cccaagttgc tgaccaccgt cacgcgtcag cggcgtccag ccaatcgccg cacggctgcg
    11161 tgtcgggcca gacgagaaga gatccaacgg taccgagaca tacacgcctt tggtgaagtc
    11221 cccttcgccg tactcctctt tcgaaacgtt ggtgatcgtg gcgtagccgc caaccaccac
    11281 gccgctatca aagcgtttgg cgatctccag cgtgccgcct ttatcccctg ccagatactg
    11341 cccgacgctg gctttcacca acacgtcctg ggcgaaagat ggcgtccagt aggcggtcag
    11401 atgtccggtt ttcacgctgt agtcggtgaa tttcatcata tcttttgcac tacgccagtc
    11461 gcgctgttta acgtagttgg catccagacc aaacgcccag ttactgtcca gcggacgata
    11521 caacacttcg gcccccgcac cgccaaacat ggtttcgaga taacctccat agacctgacc
    11581 gtagaagccg ttgcccagat gctggaagta gttggcttgc aggttattca catagacatc
    11641 gttctgcaca tactcgcgca catgggtacg aacgcgcggt aagtgcgagt cctgcggcgg
    11701 attggtgtag ttaaacttgt cgtagttgtt ggcaagattt gcaaacaggc tgccggtggt
    11761 cagcagatgg tccgtcagcc acaaatctgc cgttcccatc acgcccagct gatacatgta
    11821 aaagttttcc gggccaccga ccgactggtt cagcaccgga tcgatgtgga aatcaaagcg
    11881 tgatttgtcg atataccagc cctgctcggt ggactgcgga accactggct cgacgcgttt
    11941 ttgcgccagc ttcgtttcgt ggcccaacgg ctctccggcg agatgatttt tcaggctggc
    12001 gacatcggtt tccgtcgtca cctgcggcat gttaagacga ttttccgtaa tgcggatcgt
    12061 tttgatccca tccggcagat cgttcatcac gatccgatta gcacggatga tcccttcgcg
    12121 cgaatcacga tatttcacct gctcgccggt gacatacagc gtatcgcctt tcgcctggat
    12181 ctgcggatcg gcaagtccgg cattgtattt caacagcgtt aactgattcg ccaccaccga
    12241 atgctgcaaa atggcatcct gaggctgcgg ttgatattgc gggcgggcgt tatcgttgta
    12301 agacgggcgc agatcgttaa agttggtgcg cagcgtgacg ccaaacataa aggtgttgcc
    12361 acgttcatag ctaaggttaa cgtcggccca atcggtaacg cgataaatcg caccgacgtt
    12421 aaacttactt ttttgctcca gcttcccggc aaaatcctgc tgataattat tgccttcata
    12481 ctccagtttc aggcgcagcg gttgccaggg cgtctggtat tccacgccgc caaacagtga
    12541 ggcaggaccg tggaacatct ggctaccgtc gatagatccc gcctgtttgt agctgttatc
    12601 gcgatagcaa tatttatcac tggctgaaca gagcggattt ttcacattac cgctggtgcc
    12661 cagatatccc cagcccaggc cgagcgtaaa atcgaacggc ccccaggctt tgctggcaac
    12721 aagatattcc gcatcaaaca gccccgtacc gccgatatcc cgcgcaccaa ccgccacttg
    12781 cggcagccag taactctctt cccacaaacg cagtttgaga tcgaaggctt tatctttata
    12841 cgtttgatcg ccagagaacg cttcgacgct gctgtactgc cgggtgcgca cgtcggtgta
    12901 gcgcagcgtt gtttccagcc acgggaagag ttgcactgaa gctgagtaat aacggtactg
    12961 atcgttatcg cgatagttca gactcaactc cccttcccgt gccatacgcg cggtgggagt
    13021 ttgtaataat cctacgccac cgaaatccga ctgcgacgga ccaatgggcg caggatatgt
    13081 ttcgccgtag caagctgtgc taatgcccag cgccagtaag ctaagcagat gtcttttttt
    13141 cattattggg gtatccgctg cgtcagagtc tgaagaatgt cggcgttaag ggcatcaggc
    13201 gtctcactcc agacggagtc cgcgaggcca acataaataa tgctgccggg catcggctct
    13261 acgtgacgct tgttccagta agccaccggc gctttttgcg tgcgtccgtc cgggtaaacc
    13321 acccacgcgt agctgcgatc cgcaccgcta agcaggttct gcccggagag atagctcgcc
    13381 acgtcgcgac ctggagtgaa tggctgcttg ccaggacggc tgataagccc gaacagcgtg
    13441 accgtggacg gtggtggccc gacccacagc gtgtagttgc cctgcaacgg tgggttaccg
    13501 cgttcggcaa cgcggacgat atcaggatca agattgattt tttgcctgcc cgtcactttc
    13561 aacgcctgaa tttgctggcg taaggcgtta atcgcggcgg catcgtcggc gctggaatct
    13621 gcagccagtt ctgccagccg tgtcagcaac gcctgctgct gccgcaatgc tgccgccgtt
    13681 gccagctctt cgctaatcac cgcaccaggc caccaactgt ttgccagccg cggctggcct
    13741 accagatcga ttaaatactc tgcgcccgtc agcgttttgg cctcactgct gccattgctg
    13801 aataccttga cggttcccgc cgcgaagacc gatgacgccc ccacactcaa aatcaatgcg
    13861 acaatagttt gtttaatcat tgttttgccg ccttgatgag agtggttttc accgggaaat
    13921 aatccgcgcc gagatactgt tccgactggc gaatttgccc ttcgctgtcg atccagtagc
    13981 ggttatgcca gcgcgcctgg tcggtggaga cttcttcgtc cagcacgcga accggggttt
    14041 catcgctgcc gaccttgacg gtatcggtgc catcccattt gaagactgag cgtgcggtgg
    14101 cgtagcgtac ctgctggtac tcggtccagc ccatcgtgcg cgtccatgtt gcaccatcaa
    14161 caatttgtgc gggtttaatc agcgggtcgg cggcaaggtt attcacttca atcaggttgt
    14221 cgccgccaag caaagtcttc accagacgac catgttgtgt gacaagagtg gcttgatcct
    14281 gagtgaccca tttttgttgt ccgtcttcag cgaaggccag caccacaaac aattgcggcc
    14341 cgccattaag ctgcatgtac tggctggcgt agggcatatt ttgaatatca tcgtccgtca
    14401 gctgtacgcc tggcgtgccg aacagactgt cccacagtga attgcccagc tctttagtcg
    14461 tggctgaaca ggcctgtaat agcaggcaga taagaatgag tgcaggtcgc ttcacgactc
    14521 ttctccagag gggcagaata accacaccgg agtgtggtta tggtaaatcc cttcatactt
    14581 caagccacag atgcaatgac tcaaattatt ttggggatac atactttatt actgggtact
    14641 ggtggtcgtg gttgtggtgg tcccggtatt agaaccatca ccgccaccgg ttgccgcgag
    14701 cgcgacaccc accgccgagc ttacggtgct gacgctggtc gcggaggaac tccccgccga
    14761 aaccgacgtt gctgccgacc ctgccgcttc gcccacctgt acaggtgcag cccacgcaga
    14821 agtcgccgca agcgcagata tggcaaaaat gccatacaga acttttttca taacaatttc
    14881 ccttcattga atgaatggag atttacccaa aaacatttcg ggcgggatcg agtatacaca
    14941 actaaagcat gcgaattacg gcgcggggaa ttagagatgg ggttttagga taattggaat
    15001 gaatatcaaa tataagctac aacttatata taaataacat taaaaatcat aatgttaaaa
    15061 taaaagtaaa agtaattaat ctgagtattt tccgaaatca atcacgatta aaaatctatt
    15121 ttaggattaa cctcacggta tgatttccgt taaatcacag acaaggggat ttatctgata
    15181 aaacaatgcc gacataacgt cggcattgtt attaaggttt ttaaattaac cgcgccacgc
    15241 tttatagcgg ttaatcagac cattggtcga gctatcgtgg ctgctgattt ctttatcatc
    15301 tttcagctct ggcagaatac ggtttgccag ttgtttaccc agctccacgc cccactggtc
    15361 gaaggtgaag atgttcagga tcacgccctg agtaaagatt ttgtgctcat acagcgcaat
    15421 caacgcaccc aggctgaacg gagtgatttc acgcagcagg atggagttgg tcgggcggtt
    15481 accttcgaac actttgaacg gcaccacgta gtcaagcgtt gccggatctt taccctgatc
    15541 gcgatattcc tgctcaacca cttcgcggga tttaccaaac gccagcgctt cggtctgggc
    15601 gaagaagtta gacagcagtt tctggtgatg atcagagagc gggttatggg tgatagccgg
    15661 agcgatgaaa tcgcacggta ccattttggt tccctggtgg atcagctggt agaacgcgtg
    15721 ctgaccgtta gtgcctggtt caccccagat aatcgggcca gtctggtaat ccacaacgtt
    15781 accgttacgg tcaacatact taccgttgga ctccatattg ccctgctgga agtacgccgc
    15841 gaaacggtgc atatactggt catacggcag aatcgcctca gtttccgcac caaagaaatt
    15901 gttgtaccag atgccaatca gcgccagcag tacaggcagg tttttctcgg caggcgtggt
    15961 ggagaaatgc ttgtccatcg cgtgtgcgcc agaaagcagt tcaacgaagt tatcaaagcc
    16021 gatggagaga acaatcgaca ggccaatcgc tgaccacaaa gagtaacggc cgccgaccca
    16081 gtcccagaac tcgaacatgt tggcagtatc aataccaaac tcgccaacgg ctttggcatt
    16141 ggttgagagc gccgcaaagt gtttcgcaac gtgtttttca tcacctgccg ctttcaggaa
    16201 ccagtcacgc gcgctatggg cgttggtcat ggtttcctga gtggtgaagg ttttagatgc
    16261 taccaggaac agcgtggttt ccgggtttac ttttttcagc acttccgcga tgtgagtccc
    16321 atcgacgtta gaaacaaagt gcatgttcag gtgatttttg tacggacgca gtgcttcggt
    16381 caccatgtac gggccgaggt cagaaccgcc gatcccgatg ttcactacgt cagtgattgc
    16441 tttgccggta taacccttcc actcaccgga gataatcgct tccgagaagg ttttcatctt
    16501 ctccagcacc gcgttgactt ccggcattac gtctttgcca tcaaccaaaa tcggggtatt
    16561 gctacggtta cgcagcgcta cgtgcagcac agcgcggttt tcagtgcggt tgatcttctc
    16621 gccagagaac atcgacttaa tcgcgcccgc cagatcgcac tctttcgcca gatcttgtaa
    16681 tttcgccagc gtctcttcag tgatgcggtt tttggagtaa tccaccagca tctgatcgcc
    16741 gaaggttgcg gagaacttag aaaaacgatc gccgtcttta gcaaaaagat cggcgatcgt
    16801 aacgtctttc atttcatcga agtgtttctg tagtgcctgc caggcagcgg tctgcgttgg
    16861 attgatgttt ttcattagca atactcttct gattttgaga attgtgactt tggaagattg
    16921 tagcgccagt cacagaaaaa tgtgatggtt ttagtgccgt tagcgtaatg ttgagtgtaa
    16981 acccttagcg cagtgaagca tttattagct gaactactga ccgccaggag tggatgaaaa
    17041 atccgcatga ccccgtcgtt gacaaccgcc ccgctcaccc tttatttata aatgtactac
    17101 ctgcgctagc gcaggccaga agaggcgcgt tgcccaagta acggtgttgg aggagccagt
    17161 cctgtgataa cacctgaggg ggtgcatcgc cgaggtgatt gaacggctgg ccacgttcat
    17221 catcggctac aggggctgaa tcccctgggt tgtcaccaga agcgttcgca gtcgggcgtt
    17281 tcgcaagtgg tggagcactt ctgggtgaaa atagtagcga agtatcgctc tgcgcccacc
    17341 cgtcttccgc tcttcccttg tgccaaggct gaaaatggat cccctgacac gaggtagtta
    17401 tgtctgaaat tgttgtctcc aaatttggcg gtaccagcgt agctgatttt gacgccatga
    17461 accgcagcgc tgatattgtg ctttctgatg ccaacgtgcg tttagtagtc ctctcggctt
    17521 ctgctggtat cactaatctg ctggtcgctt tagcggaagg gctggaacct ggcgagcgat
    17581 tcgaaaaact cgacgctatt cgcaacatcc agtttgccat tctggaacgt ctgcgttacc
    17641 cgaacgttat ccgtgaagag attgaacgtc tgctggagaa cattactgtt ctggcagaag
    17701 cggcggcgct ggcaacgtct ccggcgctga cagatgagct ggtcagccac ggcgagctga
    17761 tgtcgaccct gctgtttgtc gaaatcctgc gcgaacgcga tgttcaggca cagtggtttg
    17821 atgtacgtaa agtgatgcgt accaacgacc gatttggtcg tgcagagcca gatgtagccg
    17881 cgctggcgga actggccgcg ctgcagctgc tcccacgcct caatgacggc ttagtgatca
    17941 cccagggatt tatcggtagc gaaaataaag gtcgtacaac gacgcttggc cgtggaggca
    18001 gcgattatac ggcagccttg ctggcggagg ctttacacgc atctcgtgtt gatatctgga
    18061 ccgacgtccc gggcatctac accaccgatc cacgcgtagt ttccgcagca aaacgcattg
    18121 atgaaatcgc gtttgccgaa gcggcagaga tggcaacttt tggtgcaaaa gtactgcatc
    18181 cggcaacgtt gctacccgca gtacgcagcg atatcccggt ctttgtcggc tccagcaaag
    18241 acccacgcgc aggtggtacg ctggtgtgca ataaaactga aaatccgccg ctgttccgcg
    18301 cgctggcgct tcgtcgcaat cagactctgc tcactttgca cagcctgaat atgctgcatt
    18361 ctcgcggctt cctcgcggaa gttttcggca tcctcgcgcg gcataatatt tcggtagact
    18421 taatcaccac gtcagaagtg agcgtggcat taacccttga taccaccggt tcaacctcca
    18481 ctggcgatac gttgctgacg caatctctgc tgatggagct ttccgcactg tgccgggtgg
    18541 aagtagaaga aggtctggcg ctggtcgcgt tgattggcaa tgacctgtca aaagcctgcg
    18601 gcgttggcaa agaggtattc ggcgtactgg aaccgttcaa cattcgcatg atttgttacg
    18661 gcgcatccag ccataacctg tgcttcctgg tgcccggcga agatgccgag caggtggtgc
    18721 agaagctgca ttttaatttg tttgagtaat atttccctac tggcgtataa cgctcaccga
    18781 ttgttatacg ccatcctcac tgaaaacata gattaaataa tatctgaaaa gcaaaatcac
    18841 tcctgtagaa cagtattata atcaccgaaa aatatcattt aacaggagtg ttaatggcta
    18901 ctttaatgga aaaagatgca cttttaaacg gagccagtca gtgcatcgcg tttttatcaa
    18961 atatcattga taattgctca gtttcgtcgc atcaggattc aggcgatgct ctcaagcgat
    19021 tagtcagcta tcgcgattat ctttattcta cccccgctga acttgttgat tttacacaag
    19081 gtaagattct ccttcagcag gtaagaactc aatatcagca tgaattcaac aatactacgc
    19141 attcagaaaa taaagcatct tttgattcta tttggcagcg tctgacaaat catgaagtca
    19201 caccgcaaca gcatcccatt ggttttgttt taggtgggca acccggagca ggtaaatcat
    19261 ctctgattga attagccaaa agagagacaa aagataatat aatgattatt aacggtgatg
    19321 attttcgatt tctacaccct gattttaatt atatctacca aaattatggg gatgattttg
    19381 ttacccatac agcgaaattt tccggcgaaa cggtcgaacg tgcaattgag agagcgatag
    19441 tcagtaaact caacattgtt gtcgaaggaa catttcgtaa tgccgcgacg ccgttacaaa
    19501 cattaaaaaa actcaaagat gcaggctacc aaacagaagt catgataaaa acaacctcag
    19561 cggcattaag ctgggaaagc accaatgaac ggtatagtaa ggacaaagag gcgggaaata
    19621 ttgcccgaaa agtggataaa aaccaccatg atatcgtcac cggtttgctg gcagaaaatg
    19681 cccgcaaggt gtttgcttcg aacctgtcag ataagtttgc ggtgtattcg cgtgagaaga
    19741 tgatatttag ttcacaagcg gcaacgaatg acgatattgc aacacttata cagaatgaaa
    19801 tcagcgggaa tacacaataa taataagagc tgatggcgtg aaataacgcc gggcatcacg
    19861 cccggcgcat taccgtctgg tacattaagc tatccagttc cttaacgtcc ccttctctgc
    19921 tatccggtaa cagcggtgga atttccccac gcgccagttc cgcacgaata aacgcatgta
    19981 acaatggacg gcgcggacca tattccgctt ctcctgcgcg ctgtttacgt tccagtaatt
    20041 cgtctatttc tgcacgtaac ggcgcatcaa gttcgcttcc cgccagtagc tcagcaaagc
    20101 gcattggcgg tacgcctttt cccgcttcaa cccaacgcac ggccagcagc ggacgcagca
    20161 cgtaaaagta ttttttcagc cgcacttcgt cgccttgtaa ataaccgcga aagtttttcc
    20221 gcgccatcga ataataatgc caacgcgcac gcagcggaga aaaccacttc ggcaccattg
    20281 ccttaagcgc cgttatcgtt tcttcatctt gttgatagac cacaggagaa tccagccatt
    20341 ctatcagcgt cggattcgca cctttcaata atcccagcgc cttgcgccac tcccagcctg
    20401 aaacatctaa ctcgtcgtca ataggcaact caataacatc gcgcggcgcc tctactcgca
    20461 gataccattc cagcgggtga acatacaaaa accgtacatc gtagtcgctg tcgggcgagg
    20521 caaatcccca gccgcggctc cctgattcac aggcgtacag tactttcaca tcataccgcc
    20581 gttcaatttc tcttaactgc tgcgataccc tttctcgcat cgcagcactg actccattta
    20641 atggcatgtt actcaccctt tgatattaac caacccatgc agaacctgat ccagaccgcc
    20701 aaatacagag atgttatcga tccgttcagc cactctctcc agcgtttcca gttcttttaa
    20761 gcgtaacgct accgggttgt tttccatgac tttagcggta ttgagtaacg aacgcgtcgc
    20821 tgccgtttct tcacgtcggc gaatcacatt ggcctgcgcg gatttctccg cctcaaccag
    20881 ctgcgcaagg atatttttca tatcgccagg caggacgata tctttcaccc ctaacgaggc
    20941 aatctccata ccaaatggca acatgcgcga tttcacctgt tcgctgacaa cgtcatcaat
    21001 gacctgttta tcttccagca attcatccaa cgtacgcgta cctaccgctt cacgcagggc
    21061 aaattgcaat tcccgataca aatgatcaat cggcttcgtt aactgactaa atgccagcaa
    21121 cacatcgctg tagcgccagt tagcggcgag gttaatccgc agattgacct tatctttcgt
    21181 taagatttct tgcccgctga cttccagtac ctgcaagcgg gtgtcaacca cttcagcgtc
    21241 aaccagatgg ttaattttcc agtatgcggt cagccccggc ggtaacagcg cctgcgtttc
    21301 accatcgatt ttcagcacgc ctacatgcca ggccggaacc tgcaccgtga gtatcgcatc
    21361 gcggccttta actgcccctt tgcgccgtgg ttgcaatacc gcattcatca cctccgtttg
    21421 tacctggact tgctgcgtat tcatccgcac cagtgtcaaa tcatcctcta cacgccagta
    21481 caaacggcgc gttgatggcg gcaggatctc ctgcaaaata ccgtccatat acaacgcccc
    21541 ggcttcaatc tccgacaagt ctgccaccag gcaatatttc tccacccaat caggctgaaa
    21601 gcggcgcaaa taatccgcca gcacgtcggg aacttcgctg ccatcgagcg taatcagcaa
    21661 gacttctggc gtatttaacc agggtaaaag atgctcgcct gcatgtagca ctttgtagta
    21721 atcgccgttt ctggagagta atgccagctg atcttttctt acgcttattt ttttaatcat
    21781 tatctattcc ttgcttaaca gccgtcgcgg aagcagacac gaagcgacag gggaattccc
    21841 ttttgcctgt tacccggcat ctttatcggc gacgttatcg gggatcgctg actgcgcaat
    21901 ccctcacttt ttatttaata agttaaaacc agtattcatt tcaggaatga atgtgggaat
    21961 cgaacccata attggcgtca aaggctgacg gaacacgccc ggaaaacagc ctggccgttc
    22021 ttggtgtgcc gacggggttt gacccccttt gtaattcagt ttcaacgcgt acgagatatt
    22081 gcgagaag
//
LOCUS       DAPGUL010000075        21588 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.076, whole genome shotgun sequence.
ACCESSION   DAPGUL010000075 DAPGUL010000000
VERSION     DAPGUL010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21588
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.076"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            200..1714
                     /gene="caiT"
                     /locus_tag="RHX21_003021"
     CDS             200..1714
                     /gene="caiT"
                     /locus_tag="RHX21_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine/gamma-butyrobetaine antiport BCCT
                     transporter"
                     /protein_id="HDV1988174.1"
                     /translation="MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVF
                     SYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSA
                     AVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYF
                     FFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTEC
                     MQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIV
                     SGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIF
                     LARISRGRTVRELCFGMVMGLTASTWILWTVLGSNTLLLMDKNIINIPNLIEQYGVAR
                     AIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRI
                     GWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD"
     gene            1745..2887
                     /gene="caiA"
                     /locus_tag="RHX21_003022"
     CDS             1745..2887
                     /gene="caiA"
                     /locus_tag="RHX21_003022"
                     /EC_number="1.3.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl-CoA dehydrogenase"
                     /protein_id="HDV1988175.1"
                     /translation="MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVK
                     ALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGT
                     QEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSA
                     YTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELD
                     EKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRF
                     QLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQ
                     VLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR"
     gene            3016..4233
                     /gene="caiB"
                     /locus_tag="RHX21_003023"
     CDS             3016..4233
                     /gene="caiB"
                     /locus_tag="RHX21_003023"
                     /EC_number="2.8.3.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine CoA-transferase"
                     /protein_id="HDV1988176.1"
                     /translation="MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIE
                     NVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFA
                     RRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQP
                     MPAFPYTADYFSGLTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNG
                     GEMCPRMSKGKDPYYAGCGLYKCADGYIVMELVGITQIEECFKDIGLAHLLGTPEIPE
                     GTQLIHRIECPYGPLVEEKLDAWLAAHTIAEVKERFAELNIACAKVLTVPELESNPQY
                     VARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDI
                     QELVSKGLAKVED"
     gene            4307..5860
                     /gene="caiC"
                     /locus_tag="RHX21_003024"
     CDS             4307..5860
                     /gene="caiC"
                     /locus_tag="RHX21_003024"
                     /EC_number="6.2.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308067.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetaine/carnitine-CoA ligase"
                     /protein_id="HDV1988177.1"
                     /translation="MDIIGGQHLRQMWDDLADVYGHKTALICESSGGVVNRYSYLELN
                     QEINRTANLFYTLGIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLREESA
                     WILQNSQACLLVTSAQFYPMYQQIQQEDATQLRHICLTDVALPADDGVSSFTQLKNQQ
                     PATLCYAPPLSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRDDDVYL
                     TVMPAFHIDCQCTAAMAAFSAGATFVLVEKYSARAFWGQVQKYRATITECIPMMIRTL
                     MVQPPSANDRQHRLREVMFYLNLSEQEKDAFCERFGVRLLTSYGMTETIVGIIGDRPG
                     DKRRWPSIGRAGFCYEAEIRDDHNRPLPAGEIGEICIKGVPGKTIFKEYFLNPKATAK
                     VLEADGWLHTGDTGYCDEEGFFYFVDRRCNMIKRGGENVSCVELENIIATHPKIQDIV
                     VVGIKDSIRDEAIKAFVVLNEGETLSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCS
                     GKIIRKNLK"
     gene            5969..6754
                     /gene="caiD"
                     /locus_tag="RHX21_003025"
     CDS             5969..6754
                     /gene="caiD"
                     /locus_tag="RHX21_003025"
                     /EC_number="4.2.1.149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl-CoA hydratase"
                     /protein_id="HDV1988178.1"
                     /translation="MSESLHLTRNGSILEITLDRPKANAIDAKTSFEMGEVFLNFRDD
                     PQLRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFNLDKPVIAAVN
                     GYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVM
                     TGRRMGAEEALRWGIVNRVVSQAELMDNARELAQQLVNSAPLAIAALKEIFRTTSEMP
                     VEEAYRYIRSGVLKHYPSVLHSEDAIEGPLAFAEKRDPVWKGR"
     gene            6760..7350
                     /gene="caiE"
                     /locus_tag="RHX21_003026"
     CDS             6760..7350
                     /gene="caiE"
                     /locus_tag="RHX21_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308065.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine operon protein CaiE"
                     /protein_id="HDV1988179.1"
                     /translation="MSYYAFEGVIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLR
                     GDYGRLIVQAGANIQDGCIMHGYCDTDTIVGENGHIGHGAILHGCVIGRDALVGMNSV
                     IMDGAVIGEESIVAAMSFVKAGFHGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQ
                     DLVGRCHASLHETQPLRQMEENRPRLQGTTDVTPKR"
     gene            complement(7436..7831)
                     /gene="caiF"
                     /locus_tag="RHX21_003027"
     CDS             complement(7436..7831)
                     /gene="caiF"
                     /locus_tag="RHX21_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414576.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine metabolism transcriptional regulator
                     CaiF"
                     /protein_id="HDV1988180.1"
                     /translation="MCEGYVEKPLYLLIAEWMMAENRWVIAREISIHFDIEHSKAVNT
                     LTYILSEVAEISCEVKMIPNKLEGRGCQCQRLVKVVDIDEQIYARLRNNSRDKLVGVR
                     KTPRIPAVPLTELNREQKWQMMLSKSMRR"
     gene            complement(8092..11313)
                     /gene="carB"
                     /locus_tag="RHX21_003028"
     CDS             complement(8092..11313)
                     /gene="carB"
                     /locus_tag="RHX21_003028"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HDV1988181.1"
                     /translation="MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRV
                     ILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALEL
                     ERQGVLEEFGVTMIGATADAIDKAEDRRRFDVAMKKIGLETARSGIAHTMEEALAVAA
                     DVGFPCIIRPSFTMGGSGGGIAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEM
                     EVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIG
                     VETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDE
                     LMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQ
                     ESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGAERIWYIADAFRAGLSVD
                     GVFNLTNIDRWFLVQIEELVRLEEKVAEVGITGLNAEFLRQLKRKGFADARLAKLAGV
                     REAEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEEECEANPSTDREKIMVLG
                     GGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLE
                     DVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAV
                     ERLKLKQPANATVTAIEMAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQT
                     AVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPA
                     YTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIEVNPRAARTVPFVSKA
                     TGVPLAKVAARVMAGKSLAEQGVTKEVIPPYYSVKEVVLPFNKFPGVDPLLGPEMRST
                     GEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDLAAKLLKQGFELD
                     ATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRRAIEDSRVIR
                     RSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK"
     gene            complement(11331..12479)
                     /gene="carA"
                     /locus_tag="RHX21_003029"
     CDS             complement(11331..12479)
                     /gene="carA"
                     /locus_tag="RHX21_003029"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDV1988182.1"
                     /translation="MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILT
                     DPSYSRQIVTLTYPHIGNVGTNDADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYL
                     KRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDNPDAALALEKARAFPGLNGMDLAK
                     EVTTAEAYSWTQGSWTLTGGLPEAKKEDELPFHVVAYDFGAKRNILRMLVDRGCRLTI
                     VPAQTSAEDVLKMNPDGIFLSNGPGDPAPCDYAITAIQKFLETDIPVFGICLGHQLLA
                     LASGAKTVKMKFGHHGGNHPVKDVEKNVVMITAQNHGFAVDEATLPANLRVTHKSLFD
                     GTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIELIEQYRKTAK"
     gene            complement(12935..13756)
                     /gene="dapB"
                     /locus_tag="RHX21_003030"
     CDS             complement(12935..13756)
                     /gene="dapB"
                     /locus_tag="RHX21_003030"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDV1988183.1"
                     /translation="MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSL
                     LGSDAGELAGAGKTGVTVQSSLDAVKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIG
                     TTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHH
                     RHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGTIGFATVRAGDIVG
                     EHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSSKESGLFDMRDVLDLNSL"
     gene            complement(13923..14837)
                     /gene="rihC"
                     /locus_tag="RHX21_003031"
     CDS             complement(13923..14837)
                     /gene="rihC"
                     /locus_tag="RHX21_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside hydrolase RihC"
                     /protein_id="HDV1988184.1"
                     /translation="MRLPIFLDTDPGIDDAVAIAAAIFAPELDLQLMTTVAGNVSVEK
                     TTRNALQLLHFWNAEIPLAQGAAVPLVRAPRDAASVHGESGMAGYDFVEHNRKPLGIP
                     AFLAIRDALMRAPEPVTLVAIGPLTNIALLLSQCPECKPYIRRLVIMGGSAGRGNCTP
                     NAEFNIAADPEAAACVFRSGIEIVMCGLDVTNQAILTLDYLATLPELNRTGKMLHALF
                     SHYRSGSMQSGLRMHDLCAIAWLVRPDLFTLKPCFVAVETQGEFTSGTTVVDIDGCLG
                     KPANVKVALDLDVKGFQQWVAEVLALAS"
     gene            complement(14903..15853)
                     /gene="ispH"
                     /locus_tag="RHX21_003032"
                     /gene_synonym="lytB"
     CDS             complement(14903..15853)
                     /gene="ispH"
                     /locus_tag="RHX21_003032"
                     /gene_synonym="lytB"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HDV1988185.1"
                     /translation="MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRY
                     VVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKV
                     HMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEK
                     LSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVL
                     VVGSKNSSNSNRLAELAQRMGKSAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQ
                     NVVARLQQLGGGEAITLEGREENIVFEVPKELRVDIREVD"
     gene            complement(15855..16304)
                     /gene="fkpB"
                     /locus_tag="RHX21_003033"
     CDS             complement(15855..16304)
                     /gene="fkpB"
                     /locus_tag="RHX21_003033"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HDV1988186.1"
                     /translation="MSESVQSNSAVLVHFTLKLEDGTTAESTRNNGKPALFRLGDASL
                     SEGLEQHLLGLKVGDKTTFSLEPDAAFGVPSPDLIQYFSRREFMDAGEPEIGAIMLFT
                     AMDGSEMPGVIREINGDSITVDFNHPLAGQTVHFDIEVLEIDPALEA"
     gene            complement(16392..16886)
                     /gene="lspA"
                     /locus_tag="RHX21_003034"
     CDS             complement(16392..16886)
                     /gene="lspA"
                     /locus_tag="RHX21_003034"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HDV1988187.1"
                     /translation="MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFP
                     SLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMYRSKATQKLNNIAYA
                     LIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSK
                     AKKQ"
     gene            complement(16886..19702)
                     /gene="ileS"
                     /locus_tag="RHX21_003035"
     CDS             complement(16886..19702)
                     /gene="ileS"
                     /locus_tag="RHX21_003035"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HDV1988188.1"
                     /translation="MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAA
                     KKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPI
                     ELKVEQEYGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFK
                     TEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFQAVD
                     QDALKAKFAVSNVNGPISLVIWTTTPWTLPANRAISIAPDFDYALVQIDGQAVILAKD
                     LVESVMQRIGVTDYTILGTVKGAELELLRFTHPFMGFDVPAILGDHVTLDAGTGAVHT
                     APGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVNVFKANDIVVALLQEKGA
                     LLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPDWGQA
                     RIESMVANRPDWCISRQRTWGVPMSLFVHKDTEELHPRTLELMEEVAKRVEVDGIQAW
                     WDLDAKEILGDEADQYVKVPDTLDVWFDSGSTHSSVVDVRPEFAGHAADMYLEGSDQH
                     RGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADI
                     LRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFDPAKDMVKPEEMV
                     VLDRWAVGCAKAAQEDILKAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKA
                     DSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKYVFTGEWYEGLFGL
                     ADSEAMNDAFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTLYAEPELSAKLTALG
                     DELRFVLLTSGATVADYNDAPADAQQSEVLKGLKVALSKAEGEKCPRCWHYTQDVGKV
                     AEHAEICGRCVSNVAGDGEKRKFA"
     gene            complement(19745..20686)
                     /gene="ribF"
                     /locus_tag="RHX21_003036"
     CDS             complement(19745..20686)
                     /gene="ribF"
                     /locus_tag="RHX21_003036"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HDV1988189.1"
                     /translation="MKLIRGIHNLSQAPQEGCVLTIGNFDGVHRGHRALLQGLQEEGR
                     KRNLPVMVMLFEPQPLELFATDKAPARLTRLREKLRYLAECGVDYVLCVRFDRRFAAL
                     TAQNFISDLLVKHLRVKFLAVGDDFRFGAGREGDFLLLQKAGMEYGFDITSTQTFCEG
                     GVRISSTAVRQALADDNLALAESLLGHPFAISGRVVHGDELGRTIGFPTANVPLRRQV
                     SPVKGVYAVEVLGLGEKPLPGVANIGTRPTVAGIRQQLEVHLLDVAMDLYGRHIQVVL
                     RKKIRNEQRFASLDELKAQIARDELTAREFFGLTKPA"
     gene            complement(20694..20912)
                     /locus_tag="RHX21_003037"
     CDS             complement(20694..20912)
                     /locus_tag="RHX21_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2575 family protein"
                     /protein_id="HDV1988190.1"
                     /translation="MCRHSLRSDGAGFYQLAGCEYSFSAIKIAAGGHFLPVICAMAMK
                     SHFFLISVLNRRLTLTAVQGILGRFSLF"
     gene            21015..21278
                     /gene="rpsT"
                     /locus_tag="RHX21_003038"
     CDS             21015..21278
                     /gene="rpsT"
                     /locus_tag="RHX21_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006117633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HDV1988191.1"
                     /translation="MANIKSAKKRAIQSEKARKHNASRRSMMRTFIKKVYAAIEAGDK
                     AAAQKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA"
BASE COUNT         5147 a         5808 c         5544 g         5089 t
ORIGIN      
        1 caaaattaac gagaaaagcg ccctctattc acccgaaaca aaaatgtgat aacaatcaca
       61 gaatgcagct tattgaatac ccattatgag ttagccatta acgcgtccac gaggttaata
      121 ataattatat taaatgttaa caaaaataaa acaaacggga acgcaaaata aatattcgtt
      181 ttcacagtgg aattaactca tgaagaatga aaagagaaaa acgggaatag aaccgaaggt
      241 tttctttccg ccgttaataa tcgtcggcat actttgttgg cttacagtca gagatctgga
      301 tgcagcgaat gtcgttatta atgctgtatt cagttacgtc accaatgtat ggggatgggc
      361 atttgaatgg tatatggtgg tgatgctttt cggttggttc tggctggtgt ttggcccgta
      421 tgccaaaaag cgtttaggta acgaaccacc tgaatttagt accgccagtt ggatctttat
      481 gatgttcgcc tcctgtacgt ctgctgccgt actgttctgg ggatcgattg agatctacta
      541 ctacatctcc accccgccgt ttggcttaga accgaactcg acaggggcga aagagttggg
      601 gctggcttac agcttgttcc actggggacc tctgccgtgg gccacttaca gcttcctttc
      661 agtcgccttc gcttacttct tctttgtccg caaaatggaa gtgattcgcc ccagctcgac
      721 actggtgccg ctggtaggtg aaaaacacgc caaagggttg ttcggcacta tcgtcgacaa
      781 cttctatctc gtcgccttga tcttcgcgat gggtaccagt ctgggccttg ccacgccgct
      841 ggtgaccgag tgtatgcaat ggttgtttgg cattccgcat accctgcaac tggacgctat
      901 catcattacc tgctggatta tcctcaacgc catttgcgtc gcttgcggtc tgcaaaaagg
      961 ggtacgtatc gccagtgacg tgcgtagtta cctgagcttc ctgatgctgg gttgggtgtt
     1021 cattgtcagc ggtgccagct tcatcatgaa ctacttcacc gattcggtgg ggatgttgct
     1081 gatgtatctg ccgcgaatgt tgttctatac cgatcccatc gctaaaggcg gcttcccgca
     1141 gggctggacc gtgttctact gggcatggtg ggtgatttac gccatccaga tgagtatctt
     1201 cctcgcccgc atctcccgtg gtcgtactgt gcgtgaactg tgcttcggca tggtgatggg
     1261 gctgacagca tccacctgga tcctgtggac cgtgctcggt agtaacactc tgctgttgat
     1321 ggataaaaac atcatcaaca ttccaaatct gatcgaacag tacggtgtgg cgcgcgccat
     1381 catcgaaacc tgggccgctc tgccactcag caccgccacc atgtggggct tcttcatcct
     1441 ctgctttatt gccaccgtta cgctggttaa cgcctgctct tataccctgg cgatgtccac
     1501 ttgccgcgaa gtacgcgatg gtgaagaacc accgctgctg gtgcgtatcg gttggtcaat
     1561 tctggttggc attatcggta ttgttctgct ggcgctcggc ggcctgaaac cgattcaaac
     1621 cgccattatc gccggaggat gcccgctgtt cttcgtcaac attatggtga cgctctcctt
     1681 tattaaagac gcgaaacaga actggaaaga ttaattaacc cccaaaatat caagaggttg
     1741 aaagatggat tttaatttaa atgatgagca ggaactgttt gtcgccggta tccgcgaact
     1801 gatggccagc gaaaactggg aggcctattt tgccgagtgc gaccgtgaca gcgtctaccc
     1861 ggaacgtttt gtcaaagcac tggcggatat gggtatcgac agtctgctga tccctgaaga
     1921 gcacggtggt ctggacgcgg ggtttgttac tctcgccgcc gtgtggatgg agctgggacg
     1981 tctgggggca ccaacctatg tactgtacca gttgccgggc gggttcaaca ccttcctgcg
     2041 cgaaggcaca caagagcaga tcgacaagat tatggctttc cgcggcaccg gtaagcagat
     2101 gtggaactca gcgattaccg aaccgggcgc gggctccgac gtgggtagcc tgaaaacgac
     2161 ttatacccgt agaaatggta agatttatct taatggtagt aagtgtttta ttaccagcag
     2221 cgcctacacc ccgtacatcg tggtgatggc gcgcgacggg gcttctccgg acaaacctgt
     2281 ctacaccgaa tggtttgttg atatgagcaa accgggcatc aaagtgacca aacttgaaaa
     2341 gctcggtctg cgtatggata gctgctgtga aatcaccttt gacgacgtgg aactggacga
     2401 gaaagacatg ttcggtcggg aaggtaacgg ctttaaccgc gtcaaagaag agttcgacca
     2461 tgaacgtttc ctggtagccc tgaccaacta cggtacggcg atgtgcgcct ttgaagatgc
     2521 ggcgcgctac gccaaccagc gcgtgcagtt tggcgaggct attggtcgtt tccagttgat
     2581 tcaggaaaaa ttcgcccaca tggcgatcaa attaaactcc atgaaaaaca tgctgtatga
     2641 agcagcgtgg aaagcagaca acggcaccat cacctctggc gatgcagcga tgtgcaaata
     2701 cttctgcgcc aatgcggcat ttgaagtggt ggatagcgca atgcaggtgc tgggcggtgt
     2761 cgggattgcg ggcaaccacc gcatcagccg cttctggcgt gacctgcgtg tagaccgcgt
     2821 ctccggggga tctgacgaaa tgcagatcct gacgctgggt cgtgcggtgc tgaagcaata
     2881 ccgctaagtc aatgcgctgc ctgatgcgac gctgatgcgt cttatcaggc ctacgggagc
     2941 acgaatgtag gccggataaa gcgtttacgc cgcatccggc agtcatgcgc tacataaatt
     3001 tttcaggagc aaataatgga tcatctaccc atgccgaaat tcgggccgtt ggccggattg
     3061 cgcgttgtct tctccggtat cgaaatcgcc ggaccgtttg ccgggcaaat gttcgcagaa
     3121 tggggcgcgg aagttatctg gatcgagaac gtcgcctggg ccgacaccat tcgcgttcaa
     3181 ccgaactacc cgcaactctc ccgccgcaat ttgcacgcgc tgtcgttaaa tattttcaaa
     3241 gatgaaggcc gcgaagcgtt tctgaaatta atggaaacca ccgatatctt catcgaagcc
     3301 agtaaaggtc cggcctttgc ccgtcgtggc attaccgatg aagtactgtg gcagcacaac
     3361 ccgaaactgg ttatcgctca cctgtccggt tttggtcagt acggcaccga ggagtacacc
     3421 aatcttccgg cctataacac tatcgcccag gcctttagtg gttacctgat tcagaacggt
     3481 gatgttgacc agccaatgcc tgccttcccg tataccgccg attacttttc tggcctgacc
     3541 gccaccacgg cggcgctggc agcactgcat aaagtgcgtg aaaccggtaa aggcgaaagt
     3601 atcgacatcg ccatgtatga agtgatgctg cgtatgggcc agtacttcat gatggattac
     3661 ttcaacggcg gcgaaatgtg cccgcgcatg agcaaaggta aagatcccta ctacgccggt
     3721 tgcggtctgt ataaatgcgc cgacggctac atcgtgatgg aactggtggg cattacccaa
     3781 attgaagagt gctttaaaga tattggcctc gcacatctac tcggtacgcc ggaaatcccg
     3841 gaaggcactc agcttatcca ccgtatcgaa tgcccttacg gcccactggt agaagaaaaa
     3901 ctcgatgcct ggctggcggc acataccatc gcagaagtta aagaacgctt tgccgaactg
     3961 aatatcgcct gtgccaaagt actgaccgta ccggaactgg aaagcaatcc acagtatgtt
     4021 gcccgtgaat caatcactca gtggcaaacg atggatggtc gcacctgcaa agggccgaac
     4081 atcatgccga aattcaaaaa taaccccgga caaatctggc gcggaatgcc ctcacatggc
     4141 atggacacgg ctgccatttt gaaaaatatc ggctacagcg aaaacgacat tcaggagttg
     4201 gtcagcaaag gtctggccaa agttgaggac taaacgcgtg gcgtcagtcg gcttgcctga
     4261 ctagcgcccg cccaataaca aacgaacaaa aatggataga ggtgcaatgg atatcattgg
     4321 cggacaacat ctacgtcaaa tgtgggacga tcttgcggac gtttacggtc ataaaacggc
     4381 gctgatttgt gaatccagcg gcggagtcgt taaccggtat agttatcttg agttaaatca
     4441 ggagattaac cgcacggcaa acctgtttta tacgctgggg attcgcaaag gcgacaaggt
     4501 tgcactacat ctcgacaact gcccggaatt tatcttttgc tggttcgggc tggcaaaaat
     4561 tggcgcgatt atggtgccga ttaacgcccg cctgttacgc gaggaaagcg cgtggatcct
     4621 gcaaaatagc caggcgtgcc tgctggtgac cagtgcgcaa ttctatccta tgtatcaaca
     4681 gattcagcag gaagatgcca ctcaattgcg gcacatttgc ctgacagatg tggcacttcc
     4741 cgctgatgat ggcgtgagtt cgtttactca actgaaaaat caacaacctg ccaccttgtg
     4801 ctatgcaccg ccgctatcga ctgacgatac ggcggaaatt ctcttcacct ccggcaccac
     4861 ctcccgaccg aaaggtgtgg tgattaccca ttacaacctg cgcttcgctg gatattactc
     4921 cgcctggcag tgtgcactgc gtgacgatga cgtctacctg acggtaatgc ctgcgtttca
     4981 tatcgattgc cagtgtactg cggcgatggc ggcgttttct gccggggcca cctttgtgct
     5041 ggtcgagaaa tacagcgccc gcgccttctg gggacaggtg cagaagtacc gcgccaccat
     5101 taccgaatgt attccgatga tgatccgtac gttgatggtg cagccgcctt cagcgaacga
     5161 tcggcaacac cgcctgcggg aagtgatgtt ttatctcaac ttgtcggagc aggaaaaaga
     5221 tgcgttttgt gaacgcttcg gcgttcgctt gctgacgtct tatgggatga cggaaaccat
     5281 tgtgggcatt atcggcgatc gccctggcga taaacgacgc tggccgtcga ttggtcgggc
     5341 ggggttttgc tacgaagcgg agatccgcga cgatcacaat cgcccgctcc cggcaggtga
     5401 gatcggtgaa atctgtatta aaggcgtacc agggaaaacc atcttcaaag agtattttct
     5461 caacccgaaa gccactgcga aagtgctgga agccgacggc tggctacata ccggcgatac
     5521 cggatactgc gacgaagagg gcttttttta tttcgtcgat cgccgctgca atatgatcaa
     5581 acgcggtggc gagaatgtct cctgcgtgga gctggaaaat atcatcgcca cccatccaaa
     5641 aattcaggat atcgtggttg tgggtattaa agattcgatt cgcgatgaag ccatcaaagc
     5701 atttgtggtg ctgaatgaag gtgaaacatt gagcgaagag gaatttttcc gcttctgcga
     5761 acaaaatatg gcgaaattta aagtgccctc ttatctggag atcagaaaag atctgccacg
     5821 taattgctcg gggaaaataa ttagaaagaa tctgaaataa atgaaacagc agggaactac
     5881 cctgccagct aataatcacg ctataaaaca atatgcattt tttgcaggga tgttgtcgtc
     5941 cctgaaaaag caaaaatgga gaaaaggaat gagtgaatca ttacatctga cccgcaatgg
     6001 atcaattctg gaaattaccc ttgatcgtcc aaaagcgaat gctattgatg caaaaaccag
     6061 ctttgaaatg ggcgaagtat ttctaaattt ccgtgacgat ccgcaattac gtgtcgccat
     6121 tattaccggt gccggagaga agttcttttc cgcgggctgg gatttaaaag cggcagcaga
     6181 aggcgaagca ccggatgctg actttggccc gggtggattt gcgggattaa ccgaaatttt
     6241 caatctcgac aaaccggtta tcgcagctgt gaacggctat gcctttggcg gcggtttcga
     6301 actggcgctg gcggcagatt ttattgtttg tgccgataac gccagcttcg ccctgccgga
     6361 agccaagctg ggcatcgttc ctgacagcgg cggcgtgctg cgtctaccga agatcctgcc
     6421 gcctgccatc gtcaatgaaa tggtgatgac cggcagacga atgggcgcag aagaggcgct
     6481 gcgttggggg atagtcaacc gcgtggttag ccaggcggaa ctgatggata acgcccgcga
     6541 actggcgcag cagctggtta acagcgcccc gctggcgatt gcggcgctga aagagatctt
     6601 ccgcaccacc agcgaaatgc cggtagaaga agcgtatcgc tatattcgca gcggcgtgtt
     6661 gaaacactat ccgtcggttc tgcattcgga ggatgccatt gaagggccgc tggcgtttgc
     6721 cgagaagcgc gatccggtgt ggaaaggacg ttaacaaccg tgagctatta cgcctttgag
     6781 ggggtaattc cggtggttca cccgacggcg tttgtccatc ccagtgccgt cttgattggc
     6841 gatgtgattg tgggagccgg tgtctacatc ggcccactcg cctcactgcg tggtgactac
     6901 gggcggttga tcgtgcaagc gggagccaat attcaggatg gctgcattat gcatggctac
     6961 tgcgacactg acaccatcgt tggggaaaac ggccatatcg ggcacggagc gatcctgcat
     7021 ggttgtgtga ttggtcgcga tgcattggtc gggatgaaca gcgtgattat ggatggcgcg
     7081 gtcattggcg aagagagcat tgttgccgcc atgagctttg tcaaagcagg ctttcacggc
     7141 gagaaacgcc agttgttgat gggtacgcca gcccgcgctg tacgcagtgt tagtgacgac
     7201 gagttacact ggaaacggtt gaataccaaa gagtatcagg atcttgtcgg gcgctgtcat
     7261 gcatcgttac atgaaacaca gccactgagg caaatggagg aaaatcgccc ccgtttgcag
     7321 gggacgacgg atgtgacgcc taaacggtga tcttgccgga tgcgacctgg ttgctggata
     7381 agatgctaca acatcgcatc tggcaagcag gacgcccggt atcaacgaga taaaattaac
     7441 gacgcatact ctttgacaac atcatctgcc acttctgctc gcggttaagt tccgtgagcg
     7501 gaacggcagg aatacgcggc gtctttctta cgccgactaa tttatcccgg ctgttattgc
     7561 gcaggcgcgc gtaaatttgc tcatcgatat cgaccacttt taccagtcgc tggcactggc
     7621 atccccgtcc ttccagctta ttagggatca tcttaacttc gcagcttatt tctgcgactt
     7681 ccgacagaat ataagtcagg gtattaaccg ccttgctgtg ttcaatatcg aaatgaatag
     7741 agatctctct tgctatcacc caccgatttt cagccatcat ccattcggcg attaacaagt
     7801 agagtggttt ttcaacatat ccttcacaca tacgaactcc agtttcacaa attaaaagtc
     7861 tggctatgac tcgttttgaa gcaattaaac aaggccatat taaaattgtg gatatatcga
     7921 tagtatgcaa cttcaccgtc gataagtgtg agctaaatcc tgcttatgtc atcaaaaata
     7981 tcgattcccc aaaagattta cttaatgggc aaaaaaaacg gtcctcatca gagaaccgta
     8041 ttacttattc gatcaaatta gcggatgaaa aatatccgcc atgacacgct attatttgat
     8101 ctgcgcgtgc atttcctgca ccgaaattac tttttcggtc gcgtcggcat tcagcgccat
     8161 cgcggtagcg aaaccaccgt tcagggtggt gtcataatgc actttatatt gcagcgcact
     8221 gcgacggatc acgcgggagt cttcaatcgc gcgacggcct gaagtggtgt tgatgatgta
     8281 ggtatattcg ccattcttga tgcggtcctg aatgtgcgga cggccttcat gcaccttgtt
     8341 caccagacgc ggattaatgc ccgcttcgcc cagcacaatc gccgtgccgt gggtcgcatc
     8401 cagctcgaag ccctgtttca gcagttttgc cgccaggtcc accacgcgtt ctttatcgcc
     8461 ttcgcgcacg gaaagcaacg cacgaccgtg tttcttcatg gtggagttgc tgcccagctg
     8521 cgctttggca aacgcttcag cgaaggtgcg gcccacgccc atcacttccc cggtggagcg
     8581 catttctggc cctaacagcg ggtcaacacc cgggaattta ttgaacggca gcaccacttc
     8641 tttcaccgag tagtacggcg ggataacttc tttggttacg ccctgctcag ccagcgattt
     8701 gccagccatc acacgcgccg ccacttttgc cagcggtacg ccggtggctt tggagacgaa
     8761 cggaacggta cgcgccgcac gcgggttaac ttcaatcagg tagacttcgt tgtttttcac
     8821 cgcaaactgc acgttcatca gaccgcgcac ctgcaattcg aaggccagtt tctgcacctg
     8881 ctggcgcatc acatcctgaa tttcctgact taaggtgtag gctggcagag aacatgcgga
     8941 gtcaccggag tgcacgcccg cctgctcgat gtgctccatg atgccgccaa tcagcaccat
     9001 ttcgccgtcg cagatggcat ccacgtcaac ttctaccgcg tcatcaagga agtgatccag
     9061 caacactggc gcatcgttag acacgctgac cgccgtctgg aagtagcgac gcaggtcagc
     9121 ttcgtcatag acgatttcca tcgcccgacc gccgagaacg taagacggac gtaccaccag
     9181 cgggtagcca atctctttcg ccttctctac cgccatttca atagcggtaa cggtggcgtt
     9241 cgccggttgt ttcagtttca gacgctcaac cgcatgctgg aagcgttcac ggtcttctgc
     9301 acggtcgata gcatccgggc tggtgccgat aaccggtacg ccagcagctt ccagcgcgcg
     9361 cgccagtttc agcggggtct gaccgccgta ctgaacgata acgcctttcg gcttctcaat
     9421 acgcacgatt tctagcacat cttccagagt taccggctcg aagtagaggc gatcggaagt
     9481 gtcgtagtcg gtggagacgg tttccgggtt acagttaacc ataatggttt cgtaaccgtc
     9541 ttcgcgcagc gccagcgagg cgtgtacaca gcagtagtcg aattcgatac cctgaccgat
     9601 acggttcggg ccgccgccga gaaccatgat tttttcacgg tcggtagacg gattcgcttc
     9661 gcactcttct tcataagtgg agtacatgta agcggtgtcg gtggcgaact ctgccgcaca
     9721 ggtatccacg cgcttataaa ccgggtgcag gtcatactgg tcgcgcagct tgcggatttc
     9781 cgcttcgcgc acgcccgcca gttttgccag acgcgcatcg gcaaagcctt tgcgtttcag
     9841 ctggcgcagg aattcagcgt tcaggccagt gatgcccact tccgctactt tctcttccag
     9901 acgcaccagt tcttcaatct gtaccaggaa ccagcggtca atattggtca ggttgaacac
     9961 gccgtccaca gacaggcccg cacggaaggc atcggcgatg taccagatac gctctgcgcc
    10021 agcatctttc agttcgcgac ggattttggt taacgcttcc gggtcatcga ggctcacttt
    10081 cgggtcgaat ccagtcgcac cgacttccag gccgcgcagc gctttttgca gggattcctg
    10141 ctgcgtgcga ccaatcgcca tcacttcgcc aaccgatttc atctgagtgg tcagacggtc
    10201 gttagcacca gcgaattttt cgaagttgaa gcgaggaatt ttagtaacca catagtcgat
    10261 ggacggctcg aaggaggccg gagtacgtcc gccagtgatg tcgttcatca gttcgtcgag
    10321 ggtgtaaccc accgccagtt tcgccgccac tttagcaatc gggaaaccgg tcgctttcga
    10381 cgccagcgcc gaagaacggg acacgcgtgg gttcatttcg ataacaatca ggcgaccgtt
    10441 tttcgggttc accgcaaact ggacattgga accaccggtt tcaacgccga tttcacgcag
    10501 caccgccatc gaggcgttac gcatgatttg atattctttg tcggtcagcg tttgggctgg
    10561 cgcgacagtg atggagtcac cggtatggat gcccatcgca tcaaagtttt cgatagagca
    10621 gacgatgatg cagttgtcgt ttttatcacg caccacttcc atctcgtact ctttccagcc
    10681 gatcagcgac tcatcaatca gcagctcttt ggttggggag agatccagac cgcgggcgca
    10741 aatttcttca aactcttcgc ggttataagc gataccgccg ccgctaccgc ccatggtaaa
    10801 ggatgggcga ataatgcacg ggaagcccac gtcagcggca accgccagcg cttcttccat
    10861 cgtgtgtgcg ataccggaac gcgcggtttc cagaccaatt ttcttcatcg ctacgtcgaa
    10921 acgacggcgg tcttctgctt tatcaatcgc atcggcggtc gcaccaatca tagtcacgcc
    10981 gaactcttcc aacacgccct gacgctccag ctccagcgcg cagttcagcg ccgtctgacc
    11041 gcccatcgtt ggcagcaccg cgtccgggcg ctctttttca ataatcttgc gtactacttc
    11101 ccagtgaatc ggctcgatgt aggtcgcatc ggccatttcc gggtcggtca tgatggtcgc
    11161 cgggttggag ttcaccagaa tgacgcggta accctcttcg cgcagggctt tacatgcttg
    11221 cgcgccagag tagtcaaact cacacgcctg accgataaca atcgggcccg cacccagaat
    11281 caggatactt tttatatctg tacgttttgg catggctctt ttactcctga ttacttagcg
    11341 gttttacggt actgctcaat taactcgata aagtggtcga acaacggcgc tgcgtcgtgt
    11401 ggcccagggc tggcttccgg gtgaccctgg aagctgaacg ccggtttatc agtgcgatga
    11461 atgccctgta acgtaccgtc gaacagggat ttatgcgtga cacgcaggtt tgcaggtaat
    11521 gttgcttcat ccaccgcaaa accgtggttc tgggcggtga tcatcaccac gtttttctcc
    11581 acatctttaa ccggatggtt gccgccgtgg tgaccaaatt tcattttgac agtcttcgca
    11641 ccgctcgcca gcgccagcag ctgatgaccg aggcagatgc cgaataccgg aatatcggtt
    11701 tcgaggaatt tctggatggc ggtaatggcg taatcgcacg gggccgggtc gccaggaccg
    11761 ttggagagga agatgccgtc tggattcatt ttcagcacat cttccgcaga agtttgcgcc
    11821 ggaacgatgg tcaggcgaca gcctctatcc accagcatcc gcaggatgtt gcgcttggca
    11881 ccaaaatcat aagccacgac gtggaacggc agctcgtctt cttttttcgc ttctggcagg
    11941 ccgccggtca acgtccagct cccttgtgtc cagctatagg cttctgcggt ggtcacttct
    12001 tttgccagat ccatgccatt cagacctggg aacgcgcggg ctttttctaa cgccaacgcc
    12061 gcatccgggt tatcgcctgc gataatgcag ccattctgtg cgcctttctc gcgcagtaaa
    12121 cgcgtcagct tacgggtatc gatatcggca atcgccacga tgttatggcg cttcaggtaa
    12181 gaagagaggt cttcggtatt acggaagttg ctggcaatca gcggcaggtc gcgaatcacc
    12241 agaccttgtg catgtacctg agaagattct tcatcggcgt cattagtgcc gacattgcca
    12301 atatggggat aagtaagagt aacgatttga cgagaatagg aaggatcagt gaggatttct
    12361 tgataaccgg tcattgaagt attgaaaacg acttccccaa ccgccgaacc tgttgcccct
    12421 atggcccgac cgtgaaactg ggttccgtct tccagaacca atagcgctga cttaatcaaa
    12481 acaccctcca gagaatattc actcacttta tttgcatatt aattcacaat gatgacgtaa
    12541 atcaatgcaa atctgcttac cgacgaattt ctggcaaacg gcggcattct ggagatatgg
    12601 gcgctaaaag tcaacttaat ggcgggattt tttatattat tttgtggctc atgcatgttt
    12661 tacaggcatt aagcggcaaa aagatcatat aacctgttct agaaaacgct tgcgcagcaa
    12721 gaagattgca tgaaataaaa gcgagtaggg aaaagtggac caaatggtca aaatttacat
    12781 taaaacaaca aaaaccgaag acaaaacatg taatttttgg cacttataga caatttaaaa
    12841 acataacact aaaaataaaa gggccaaaaa ttaaagccct ttataatcaa taaattaaat
    12901 gtgttattct tgcaccataa caaatatttt gtggttacaa actattgaga tcaagcacat
    12961 ctcgcatatc aaaaagacca ctttccttac tactcaacca caaagccgat cttaccgcgc
    13021 cgttagcaaa tgtcatgcgg ctggacgcct tatgggtgat ctccagacgc tcgccaatat
    13081 cggcaaacat cgcggtatgt tcgccaacga tgtcacctgc acgcacggtg gcaaaaccaa
    13141 tggtgccagg cacacgttca ccggtgtggc cttcacgact gtagaccgcg caatctttca
    13201 gatctttatc aagggcgtgg gcgatcgcct ctcccattgc cagtgcggtg cctgacggcg
    13261 catcaacttt atgtctatga tgtgcttcaa taatttcgat atcggtgtag tcacccatca
    13321 ctttggctgc tttctccagc agcttaagca tgacgttaac gccaacgcta aaattggcgg
    13381 caaagacaat cgcaatatcg gcggcggcgt cacgaatcgc ctgtttaccg gcttcgtcaa
    13441 accccgtagt gccgatcacc atccctttgc catgctggcg acaaaaagcg agatggttca
    13501 gcgtaccttc cggacgggta aaatcgataa acacatcaaa atcatctttt accgcatcga
    13561 ggctgctttg cacggtaacg cctgttttcc ctgcaccagc cagctcaccg gcgtcgctgc
    13621 ccagtaaaga agatccttcg cgctccagcg ccgcgcccag ctgcacgcct tctaatgcca
    13681 gcgccgcctg aatcaactgg cggcccatac gccccccggc tcccgcgatg gcaacgcgga
    13741 tgtttgcatc atgcatagct attctctttt gttaatttgc atagaccgtt ttcagagtaa
    13801 ccagcgcatc gctacgccgc cagccaaaaa cgctgataat tagaaattaa tgataaacag
    13861 ggagggatat cagtgaaagg catgagtcga tgaatgactg catgccgata acatgtgaca
    13921 ggttacgacg ccagagccag cacctcagcc acccactgct ggaagccttt cacatccaga
    13981 tccaatgcca cctttacatt ggctggtttg cccaggcaac cgtcgatatc aaccaccgtc
    14041 gtgcctgagg taaattcgcc ttgagtttct accgcgacaa aacacggctt gagggtgaat
    14101 aagtccgggc gcaccagcca ggcgatggcg cagagatcgt gcattcgcag accgctttgc
    14161 atactgccgc tacggtagtg gctaaacagt gcatgaagca tttttccggt gcgattcaac
    14221 tccggcaaag tagcgagata gtcaagggtt aatattgcct gattggtgac atccagaccg
    14281 cacatgacga tttcgattcc gctacggaag acacaggcag ccgcttctgg atcggcagcg
    14341 atattaaact cggcgtttgg cgtacagttg ccgcgtccgg cagaaccacc catgatcacc
    14401 agacggcgaa tatacggctt gcattccggg cattgtgaaa gtaacagcgc aatattggtt
    14461 aacgggccaa tggccaccag ggtaacaggc tctggtgcac gcatcagggc atcccgaatc
    14521 gccagaaacg ccggtatccc gagcggcttt cggttgtgct caacaaagtc gtagccagcc
    14581 attcccgatt cgccgtgcac agatgccgca tcacgcggtg cgcgtaccag cggcacagcg
    14641 gccccttggg cgagcggaat ctccgcattc cagaaatgca gcagttgcag ggcattgcgg
    14701 gtagttttct caaccgagac attacccgcg acggtggtca tcagttgcag gtcgagttcg
    14761 ggtgcaaaaa tcgcggcggc aatggcgacg gcatcgtcaa tgccggggtc agtatcgagg
    14821 aagataggta aacgcatgtt ttctccataa aaaatgccgg taacaagacc ggcattttcg
    14881 cataacttag gctgctaatg acttaatcga cttcacgaat atcgacacgc agctctttcg
    14941 gcacttcgaa aacaatgttt tcttcacgtc cttccagcgt aatggcttca ccaccgccca
    15001 gctgttgcaa acgtgccacc acattctgca ccagaatatc cggagccgat gcgcccgcag
    15061 tcacgccgac gcatttaacc tctttcaccc actcttcctg gatatctttc gcatcatcaa
    15121 tcaaaaacgc gcttttgccc atacgctggg ccagctccgc cagacggttg gagttagagg
    15181 agtttttcga accgaccacc agcacaactt ccgcctgttc ggccagggca cgtaccgctt
    15241 cctgtcggtt agtcgtggcg tagcagatgt catctttgcg cggaccgaca attttcggga
    15301 agcgtttacg cagcgcgtcg atcacatcag acgtgtcatc caccgacagc gtggtctggg
    15361 tcataaagga gagtttctct tcgtttttga ccgtcagttt ccacacatcg tctggtgatt
    15421 caaccagata cattccccct tccgggttgc tgtactgacc catcgtgcct tccacttccg
    15481 ggtgcccggc gtgaccgatg agaatagatt cttcgccacg gcgactagcg cgggcgactt
    15541 ccatatgcac tttggtcacc agcggacagg tcgcgtcaaa taccgtcaaa tcgcgacttt
    15601 ttgcttcgtt acgtaccgcc tgagaaacac cgtgtgcgga gaaaatcagg atcgcgccgt
    15661 ccggtacttc gctaatctgc tcaataaaga tagccccacg ctcacgcaag ctatcgacca
    15721 catagcggtt atgtaccact tcgtgacgga catatatcgg tgcgccgtaa atggccagcg
    15781 cgttttcaac aatgctgata gcgcggtcta ccccggcaca aaaaccacgc gggttggcca
    15841 acaggatctg catgttacgc ctccagtgcc ggatcgattt ccagcacttc aatatcaaaa
    15901 tgaacggtct gcccggccag cggatggttg aaatcaacgg taatggagtc gccgttaatt
    15961 tcgcggatca cgccaggcat ctcactgcca tccattgcgg taaaaagcat gattgcgcca
    16021 atttctggct cgcctgcatc cataaattca cggcgggaga agtactgaat caggtccggt
    16081 gacggcacgc caaacgccgc atctggctcc aacgagaagg tggttttatc gcccactttc
    16141 agccccaaca ggtgttgctc cagcccttca gaaagagaag catcacccag gcggaacagc
    16201 gccggtttac cgttgttgcg ggtagactcg gcggtggtgc catcctcgag ttttagcgtg
    16261 aagtgcacca ggacggcgct attgctctgt acagattcag acatgcaggt ttgctcttat
    16321 attttgagga tttttgccgg atgcggccta cgatttcgca gcaatctgta ggccttatcc
    16381 ggcagggttt attattgttt tttcgcttta gaaggcaaaa aaccttccag cacaatcagt
    16441 gccgcaccga cacaaatggc agtatcggca aggttgaagg tggcgaagtg ccagtcgccg
    16501 acgtagaagt cgatcatatc gacaacgaag ccgtgccaca ggcggtcgaa caggttgccc
    16561 agcgcgccgc caataatcag cgcataagcg atattgttta gcttctgcgt ggccttcgag
    16621 cgatacatca tcactgccag gatcacgcta ataccaatcg caataccggc aaagaaccaa
    16681 cgctgccagc cgccgctatc ggcaaggaaa ctaaacgccg cgccatagtt acgcgcataa
    16741 tgcagattaa gcgacgggaa cagcgggacc gtatccccca gagcaaagtt ctggaggatc
    16801 aggtatttgc tgcccagatc gataatcagc acgactacca ccagccacag ccagcgtagc
    16861 cctgttgaac agatcgattg actcatcagg caaacttacg tttttcaccg tcaccggcga
    16921 cgttgctgac acagcggccg cagatttctg cgtgttccgc caccttgccg acatcctggg
    16981 tgtagtgcca gcagcgtggg cacttctcac cttcggcttt actcaacgcg actttcagcc
    17041 ctttgagtac ttcgctctgc tgagcatcag caggtgcgtc gttatagtct gcaacggtag
    17101 cgccggaggt caacaggaca aatcgtaatt catcgcccag cgcggtcagt ttcgccgaca
    17161 gttccggttc tgcatacaag gttactgccg cttccagcga gccacccact ttcttgtcgg
    17221 cacgcgcttg ctcaatgact ttgttcactt cgccacgcac tttcaacagc tcgtcccaga
    17281 acgcatcgtt catcgcttca ctgtctgcca gaccaaacag gccttcgtac cactcaccgg
    17341 taaagacgta tttttcacgt tcgcccggca ggtagcccca cacttcatca gcggtgaagg
    17401 agaggattgg tgccatccag cgcaccagcg cttctgcgat gtgatacagc gcagtctggc
    17461 agctacgacg cgccacactg tccgctttgg cggtgtactg acggtctttg atgatgtcga
    17521 ggtagaagga acccatctca acggagcaga agcgcatcag acgctgtacc acttcgtgga
    17581 aatcgtatgc ttcgtacgcc ttgaggatgt cttcctgtgc cgctttcgca caacctacgg
    17641 cccagcgatc cagtaccacc atctcttccg gtttcaccat atcttttgcc ggatcaaaac
    17701 cgttcaggtt tgccagcagg aagcgcgcgg tgttacggat acgacgatag ctgtcggcag
    17761 cacgtttcag gatctcatca gaaacggcca tttcaccggt gtagtcagtt gatgccaccc
    17821 acagacgcag aatatccgcg cccagtttgt tcatcacatc ctgcggcgaa acggtgttgc
    17881 cgatggattt agacatcttg cgaccctgac catccacggt aaagccgtgg gtcagtacct
    17941 gacgatacgg cgctttgcct ttcatcgcgg tggagatcat cagggaagac atgaaccaac
    18001 cacggtgctg gtcagaacct tccagataca tgtccgctgc gtgaccggca aattccggac
    18061 gcacgtcaac aacagaagag tgggtagatc cggagtcaaa ccatacatcc aatgtgtccg
    18121 gcactttcac gtactgatca gcttcatcgc cgaggatctc tttcgcatca agatcccacc
    18181 acgcctggat gccgtcaact tcaacgcgtt ttgccacttc ttccattagt tcgagagtac
    18241 gcggatgcag ctcttccgtg tctttgtgca cgaacagtga catcggtacg ccccaggtgc
    18301 gctgacggga gatacaccag tcaggacggt tagcaaccat cgactcgata cgcgcctggc
    18361 cccagtccgg gatccactgc acgcctttga tctctttcag tgactgcgca cgcagacctt
    18421 tctgatccat gctgacgaac cactgcggcg tcgcgcggaa gatgatcggc gttttgtgac
    18481 gccagcagca cggatagctg tgctgcattt tctcaacgtg cagcagcgcg cctttttcct
    18541 gcagcagcgc aacgacgatg tcgttcgctt tgaagacgtt cacgccatcc agcgtcggat
    18601 aagtgcccgg cagataagtg ccgtccgggc caaccgggtt agcggtttcc aggccgtatt
    18661 tctgaccgat cacatagtcg tccgggccgt ggccaggcgc ggtgtgaacg gcaccggtac
    18721 cggcatccag ggtaacgtga tcgccgagga ttgccggaac gtcgaagccc ataaacggat
    18781 gggtaaagcg cagcaactca agctccgcac cttttaccgt gccgagaatg gtgtaatcgg
    18841 tcacgccgat acgctgcatt acgctttcaa ccagatcttt cgccagaatc acggcctgac
    18901 cgtcgatctg caccagcgca tagtcgaaat caggtgcaat agagattgcg cggttcgcag
    18961 gcagagtcca cggcgtagtg gtccagatca ccagcgagat tgggccgtta acgttgctta
    19021 cggcaaattt tgctttcagt gcatcctgat cgaccgcctg aaaagcaacg tcgatggacg
    19081 gagaagtttt gtcgtaatac tcaacttccg cttccgccag cgcagaacgg cagtcaacgc
    19141 accagtgaac tggcttcgcg cctttgtgca ggtgaccgtt gccgatgatt ttgcccagcg
    19201 cgcggatgat gttggcttca gttttgaagt ccatggtcag gtacgggtgc gaccagtcgc
    19261 ccagcacgcc cagacggata aagtctttgc gttgaccgtc aacctgggtc gccgcgtatt
    19321 cgcggcactt ggcgcggaac tcggcggcgg tgaatttctc acccggctta ccgtattctt
    19381 gctctacttt cagctcgatc ggcagaccgt ggcagtccca gccaggcaca tacggcgagt
    19441 cataaccgga aagccctttg gacttcacga taatgtcttt cagaatcttg ttaaccgagt
    19501 gaccaatatg aatgctgcca ttcgcataag gagggccatc atgcagaatg aaggtttttt
    19561 tgcctttttt agccgcacgg atgatgccgt acagatcatc atcagtccaa cgcgccagca
    19621 ttcccggttc gcgcttggcg agatcgccac gcatcgggaa ccctgtttcc ggcaaattca
    19681 gggttgattt atagtcactc atcagattct cggttccgtg tttcggtttg attacataac
    19741 aggcttaagc cggttttgtt agcccaaaaa attcgcgggc ggttaattca tcacgcgcaa
    19801 tctgcgcttt cagttcgtcc agcgacgcaa atcgctgctc attgcgtatt tttttacgca
    19861 gcactacttg tatatggcga ccgtaaaggt ccattgcaac atctaacaaa tgcacttcca
    19921 gctgctggcg aataccggca accgttgggc gtgttccaat gtttgccacg ccgggtaacg
    19981 gcttttcacc gaggcccagc acttctaccg cataaacccc tttcaccggg gaaacctgac
    20041 ggcgtagcgg tacattcgcc gtcgggaaac ctatagtgcg ccctaattca tcaccgtgga
    20101 ctacacgccc ggagatggca aacgggtgcc ccagtaaact ttctgccaga gccagattgt
    20161 catccgccag cgcctgacgc acagcggtgc tgctgatacg cacgccacct tcgcaaaaag
    20221 tttgcgtact ggtgatatcg aagccgtatt ccatgccagc tttctgtaat aacaagaaat
    20281 cgccttcacg accagcgcca aagcggaaat catcacctac ggcaagaaat tttacgcgca
    20341 aatgcttcac cagaagatcg ctgatgaaat tttgcgcggt taacgccgcg aaacgcctgt
    20401 cgaaacgcac gcacagcacg taatcaacgc cacactctgc aaggtaacgc agtttttccc
    20461 gcagccgggt cagccgtgcc ggggctttat cggtagcaaa cagttccagt ggttgaggtt
    20521 caaaaagcat caccatcacc ggtaagttgc gcttgcgccc ttcttcctgc aagccctgta
    20581 acagcgcgcg atgaccgcga tgcacgccgt cgaaattacc aatagtcagc acacaccctt
    20641 cttgcggggc ctggctgaga ttatgtatgc cgcgtatcag cttcatgtct ggctcaaaac
    20701 agtgaaaatc gtccgagtat accttgtaca gcggtcaagg ttaaccggcg attgagtacc
    20761 gaaatcagaa agaagtggct tttcattgcc atggcgcaaa tcacgggaag aaagtgaccg
    20821 cctgctgcaa tttttatcgc ggaaaagctg tattcacacc ccgcaagctg gtagaatcct
    20881 gcgccatcac tacgtaacga gtgccggcac attaacggcg cttatttgca caaatccatt
    20941 gacaaaagaa ggctaaaagg gcatattcct cggcctttga attgtccata tagaacacat
    21001 ttgggagttg gaccttggct aatatcaaat cagctaagaa gcgcgccatt cagtctgaaa
    21061 aggctcgtaa gcacaacgca agccgtcgct ctatgatgcg tactttcatc aagaaagtat
    21121 acgcagctat cgaagctggc gacaaagctg ctgcacagaa agcatttaac gaaatgcaac
    21181 cgatcgtgga ccgtcaggct gctaaaggtc tgatccacaa aaacaaagct gcacgtcata
    21241 aggctaacct gactgcacag atcaacaaac tggcttaatc gccaatttgc tgaagctttg
    21301 tgaaaaagcc cgcgcaagcg ggttttttta tgcctgctgc ttttatgatg cgtgagagaa
    21361 cacactaccg gttgccagat agtcaaaaga tgctggcttt tgcagacatg ccgttacact
    21421 ttctgaactc ttcgtggctt aagaatcgta gaaccatcgg ctgatacatt ctgaacaaga
    21481 atatctactc aatctccaga ctcccctaca aagaatgtgg atattgtgat acacattgag
    21541 gtattaaact taaggccact ctatttttga attaaattcc tatacact
//
LOCUS       DAPGUL010000076        21438 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.077, whole genome shotgun sequence.
ACCESSION   DAPGUL010000076 DAPGUL010000000
VERSION     DAPGUL010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21438
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.077"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..185)
                     /locus_tag="RHX21_003039"
     CDS             complement(<1..185)
                     /locus_tag="RHX21_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_305405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HDV1988192.1"
                     /translation="MFPLNDLSLKTQSVQLNKVTSNTESTIKQHELVSDDAIINELSS
                     ELVSCLGNGKFTPISED"
     gene            complement(536..850)
                     /gene="fliE"
                     /locus_tag="RHX21_003040"
     CDS             complement(536..850)
                     /gene="fliE"
                     /locus_tag="RHX21_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HDV1988193.1"
                     /translation="MSAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDR
                     ISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSM
                     QV"
     gene            1065..2723
                     /gene="fliF"
                     /locus_tag="RHX21_003041"
     CDS             1065..2723
                     /gene="fliF"
                     /locus_tag="RHX21_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HDV1988194.1"
                     /translation="MNATAAQTKSLEWLNRLRANPKIPLIVAGSAAVAVMVALILWAK
                     APDYRTLFSNLSDQDGGAIVSQLTQMNIPYRFSEASGAIEVPADKVHELRLRLAQQGL
                     PKGGAVGFELLDQEKFGISQFSEQVNYQRALEGELSRTIETIGPVKGARVHLAMPKPS
                     LFVREQKSPSASVTVNLLPGRALDEGQISAIVHLVSSAVAGLPPGNVTLVDQGGHLLT
                     QFNTSGRDLNDAQLKYASDVEDRIQRRIEAILSPIVGNGNIHAQVTAQLDFASKEQTE
                     EQYRPNGDESHAALRSRQLNESEQSGSGYPGGVPGALSNQPAPANNAPISTPPANQNN
                     RQQQASTTSNSGPRSTQRNETSNYEVDRTIRHTKMNVGDVQRLSVAVVVNYKTLPDGK
                     PLPLSNEQMKQIEDLTREAMGFSEKRGDSLNVVNSPFNSSDESGGELPFWQQQAFIDQ
                     LLAAGRWLLVLLVAWLLWRKAVRPQLTRRAEAMKAVQQQAQAREEVEDAVEVRLSKDE
                     QLQQRRANQRLGAEVMSQRIREMSDNDPRVVALVIRQWINNDHE"
     gene            2716..3711
                     /gene="fliG"
                     /locus_tag="RHX21_003042"
     CDS             2716..3711
                     /gene="fliG"
                     /locus_tag="RHX21_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HDV1988195.1"
                     /translation="MSNLTGTDKSVILLMTIGEDRAAEVFKHLSQREVQTLSAAMANV
                     TQISNKQLTDVLAEFEQEAEQFAALNINANDYLRSVLVKALGEERAASLLEDILETRD
                     TASGIETLNFMEPQSAADLIRDEHPQIIATILVHLKRAQAADILALFDERLRHDVMLR
                     IATFGGVQPAALAELTEVLNGLLDGQNLKRSKMGGVRTAAEIINLMKTQQEEAVITAV
                     REFDGELAQKIIDEMFLFENLVDVDDRSIQRLLQEVDSESLLIALKGAEQPLREKFLR
                     NMSQRAADILRDDLANRGPVRLSQVENEQKAILLIVRRLAETGEMVIGSGEDTYV"
     gene            3704..4390
                     /gene="fliH"
                     /locus_tag="RHX21_003043"
     CDS             3704..4390
                     /gene="fliH"
                     /locus_tag="RHX21_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416450.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HDV1988196.1"
                     /translation="MSDNLPWKTWTPDDLAPPQAEFVPMVEPEETIIEEAEPSLEQQL
                     AQLQMQAHEQGYQAGIAEGRQQGHEQGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLV
                     SEFQTTLDALDSVIASRLMQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGK
                     PQLRVHPDDLQRVDDMLGATLSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQE
                     LCRLAAPGVV"
     gene            4390..5763
                     /gene="fliI"
                     /locus_tag="RHX21_003044"
     CDS             4390..5763
                     /gene="fliI"
                     /locus_tag="RHX21_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellum-specific ATP synthase FliI"
                     /protein_id="HDV1988197.1"
                     /translation="MTTRLTRWLTTLDNFEAKMAQLPAVRRYGRLTRATGLVLEATGL
                     QLPLGATCVIERQNGSETHEVESEVVGFNGQRLFLMPLEEVEGVLPGARVYAKNISAE
                     GLQSGKQLPLGPALLGRVLDGSGKPLDGLPSPDTTETGALITPPFNPLQRTPIEHVLD
                     TGVRPINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTRADVIVVGLIGERGREVKD
                     FIENILGAEGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTR
                     YAMAQREIALAIGEPPATKGYPPSVFAKLPALVERAGNGISGGGSITAFYTVLTEGDD
                     QQDPIADSARAILDGHIVLSRRLAEAGHYPAIDIEASISRAMTALISEQHYARVRTFK
                     QLLSSFQRNRDLVSVGAYAKGSDPMLDKAIALWPQLEGYLQQGIFERADWEASLQGLE
                     RIFPTVS"
     gene            5782..6225
                     /gene="fliJ"
                     /locus_tag="RHX21_003045"
     CDS             5782..6225
                     /gene="fliJ"
                     /locus_tag="RHX21_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis chaperone FliJ"
                     /protein_id="HDV1988198.1"
                     /translation="MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLID
                     YQNEYRNNLNSDMSAGMTSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWR
                     EKKQRLQAWQTLQERQSTAALLAENRLDQKKMDEFAQRAAMRKPE"
     gene            6222..7349
                     /gene="fliK"
                     /locus_tag="RHX21_003046"
     CDS             6222..7349
                     /gene="fliK"
                     /locus_tag="RHX21_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook length control protein FliK"
                     /protein_id="HDV1988199.1"
                     /translation="MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTD
                     KAAPQLLVATDKPTTKGEPLVSEILADAQQADLLIPVDETPPVINDEQSTSTPLTTAQ
                     TMTLAAVAGNNTAKDEKADDLNEDVTASLSALFAMLPGFDNTPKVTDVPSTVLPAEKP
                     TLFTKLTSAQLTTAQPDDAPGTPAQPLTPLVAEAQSKAEVISTPSPVTAAASPLITPH
                     QTQPLPTVAAPVLSAPLGSHEWQQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLK
                     VDDNQAQIQMVSPHQHVRAALEAALPVLRTQLAESGIQLGQSNISGESFSGQQQAASQ
                     QQQSQRTANHEPLAGEDDDTLPVPVSLQVRVTGNSSVDIFA"
     gene            7454..7918
                     /gene="fliL"
                     /locus_tag="RHX21_003047"
     CDS             7454..7918
                     /gene="fliL"
                     /locus_tag="RHX21_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated protein FliL"
                     /protein_id="HDV1988200.1"
                     /translation="MTDYAISKKSKRSLWIPILVFITLAACASAGYSYWHSHQVAADD
                     KAQQRVVPSPVFYALDTFTVNLGDADRVLYIGITLRLKDEATRSRLSEYLPEVRSRLL
                     LLFSRQDAAVLATEEGKKNLIAEIKTTLSTPLVAGQPKQDVTDVLYTAFILR"
     gene            7923..8927
                     /gene="fliM"
                     /locus_tag="RHX21_003048"
     CDS             7923..8927
                     /gene="fliM"
                     /locus_tag="RHX21_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliM"
                     /protein_id="HDV1988201.1"
                     /translation="MGDSILSQAEIDALLNGDSEVKDEPTASVSGESDIRPYDPNTQR
                     RVVRERLQALEIINERFARHFRMGLFNLLRRSPDITVGAIRIQPYHEFARNLPVPTNL
                     NLIHLKPLRGTGLVVFSPSLVFIAVDNLFGGDGRFPTKVEGREFTHTEQRVINRMLKL
                     ALEGYSDAWKAINPLEVEYVRSEMQVKFTNITTSPNDIVVNTPFHVEIGNLTGEFNIC
                     LPFSMIEPLRELLVNPPLENSRNEDQNWRDNLVRQVQHSQLELVANFADISLRLSQIL
                     KLKPDDVLPIEKPDRIIAHVDGVPVLTSQYGTLNGQYALRIEHLINPILNSLNEEQPK
                     "
     gene            8924..9337
                     /gene="fliN"
                     /locus_tag="RHX21_003049"
     CDS             8924..9337
                     /gene="fliN"
                     /locus_tag="RHX21_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliN"
                     /protein_id="HDV1988202.1"
                     /translation="MSDMNNPADDNNGAMDDLWAEALSEQKSTSSKSAADAVFQQFGG
                     GDVSGTLQDIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILIN
                     GYLIAQGEVVVVADKYGVRITDIITPSERMRRLSR"
     gene            9340..9705
                     /gene="fliO"
                     /locus_tag="RHX21_003050"
     CDS             9340..9705
                     /gene="fliO"
                     /locus_tag="RHX21_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310713.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FliO"
                     /protein_id="HDV1988203.1"
                     /translation="MNNHATVQSSAPVSAAPLLQVSGALIAIIALILAAAWLVKRLGF
                     APKRTGVNGLKISASASLGARERVVVVDVEDARLVLGVTAGQINLLHKLPPSAPTEEI
                     PQTDFQSVMKNLLKRSGRS"
     gene            9705..10442
                     /gene="fliP"
                     /locus_tag="RHX21_003051"
     CDS             9705..10442
                     /gene="fliP"
                     /locus_tag="RHX21_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310714.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HDV1988204.1"
                     /translation="MRRLLSVAPVLLWLVTPLAFAQLPGITSQPLPGGGQSWSLPVQT
                     LVFITSLTFIPAILLMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMS
                     PVIDKIYVDAYQPFSEEKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQ
                     GPEAVPMRILLPAYVTSELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIA
                     LPFKLMLFVLVDGWQLLVGSLAQSFYS"
     gene            10452..10721
                     /gene="fliQ"
                     /locus_tag="RHX21_003052"
     CDS             10452..10721
                     /gene="fliQ"
                     /locus_tag="RHX21_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013365797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HDV1988205.1"
                     /translation="MTPESVMMMGTEAMKVALALAAPLLLVALVTGLIISILQAATQI
                     NEMTLSFIPKIIAVFIAIIIAGPWMLNLLLDYVRTLFTNLPYIIG"
     gene            10730..11515
                     /gene="fliR"
                     /locus_tag="RHX21_003053"
     CDS             10730..11515
                     /gene="fliR"
                     /locus_tag="RHX21_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FliR"
                     /protein_id="HDV1988206.1"
                     /translation="MMQVTSDQWLSWLSLYFWPLLRVLALISTAPILSERSVPKRVKL
                     GLAMMITFAIAPSLPANDVPVFSFFALWLAVQQILIGVALGFTMQFAFAAVRTAGEII
                     GLQMGLSFATFVDPASHLNMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIG
                     GEPLNSNAFLALTKAGSLIFLNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGF
                     PLTLTVGISLMAALMPLIAPFCEHLFSEIFNLLADIISELPLI"
     gene            11805..12428
                     /gene="rcsA"
                     /locus_tag="RHX21_003054"
     CDS             11805..12428
                     /gene="rcsA"
                     /locus_tag="RHX21_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RcsA"
                     /protein_id="HDV1988207.1"
                     /translation="MSTIIMDLCSYTRLDLTGYLLSRGVKKREINDIETVDDLAIACD
                     SQRPSVVFINEDCFIHDASNSQRIKHIINQHPNTLFIVFMAIANVHFDEYLLVRKNLL
                     ISSKSIKPESLDDILGDILKKETTITSFLNMPTLSLSRTESSMLRMWMAGQGTIQISD
                     QMNIKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFVNMR"
     gene            complement(12472..12660)
                     /gene="dsrB"
                     /locus_tag="RHX21_003055"
     CDS             complement(12472..12660)
                     /gene="dsrB"
                     /locus_tag="RHX21_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DsrB"
                     /protein_id="HDV1988208.1"
                     /translation="MKVNDRVTVKTDGGPRRPGVVLAVEEFSEGTMYLVSLEDYPLGI
                     WFFNEAGHQDGIFVEKAE"
     gene            12823..13050
                     /gene="yodD"
                     /locus_tag="RHX21_003056"
     CDS             12823..13050
                     /gene="yodD"
                     /locus_tag="RHX21_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416463.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide/acid resistance protein YodD"
                     /protein_id="HDV1988209.1"
                     /translation="MKTAKEYSDTAKREVSVDVDALLAAINEISESEVHRSQNDSEHV
                     SVDGREYHTWRELADAFELDIHDFSVSEVNR"
     gene            13348..14163
                     /locus_tag="RHX21_003057"
     CDS             13348..14163
                     /locus_tag="RHX21_003057"
                     /EC_number="3.1.3.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-3-phosphoglycerate phosphatase-related
                     protein"
                     /protein_id="HDV1988210.1"
                     /translation="MFSIQQPLLVFSDLDGTLLDSHSYDWQPAAPWLSRLREANVPVI
                     LCSSKTSAEMLYLQKTLGLQGLPLIAENGAVIQLAEQWQDIDGFPRIISGISHGEISQ
                     VLNTLREKEHFKFTTFDDVDDATIAEWTGLSRSQAALTQLHEASVTLIWRDSDERMAQ
                     FTARLNELGLQFMQGARFWHVLDASAGKDQAANWIIATYQQLSGKRPTTLGLGDGPND
                     APLLEVMDYAVIVKGLNREGVHLHDEDPARVWRTQREGPEGWGEGLDHFFSAR"
     gene            complement(14160..15854)
                     /gene="yedQ"
                     /locus_tag="RHX21_003058"
     CDS             complement(14160..15854)
                     /gene="yedQ"
                     /locus_tag="RHX21_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis regulator YedQ"
                     /protein_id="HDV1988211.1"
                     /translation="MQHETKMENQSWLKKLARRLGPGHVVNLCFIVVLLFSTLLTWRE
                     VVVLEDAYISSQRNHLENVANALDKHLQYNVDKLIFLRNGMREALVAPLDFTSLRNAV
                     TEFEQHRDEHAWQIELNRRRTLSVNGVSDALVSEGNLLSRVNESLDNEITAALEVGYL
                     LRLAHNTSSMVEQAMYVSRAGFYVSTQPTLFTRNVPTRYYGYVTQPWFIGHSQRENRH
                     RAVRWFTSQPEHASNTEPQVTVSVPVDSNNYWYGVLGMSIPVRTMQQFLRNAIDKNLD
                     GEYQLYDSKLRFLTSSNPDHPTGNIFDPRELALLAQAMEHDTRGGIRMDSRYVSWKRL
                     DHFDGVLVRVHTLSEGVRGDFGSISIALTLLWALFTTMLLISWYVIRRMVSNMYVLQS
                     SLQWQAWHDTLTRLYNRGALFEKARPLAKLYQTHQHPFSVIQVDLDHFKAINDRFGHQ
                     AGDRVLSHAAGLISSSLRAQDVAGRVGGEEFCVILPGASLTEAAEVAERIRLKLNEKE
                     MLIAKSTTIRISASLGVSSSEETGDYDFEQLQSLADRRLYLAKQAGRNRVCASDNA"
     gene            complement(16025..16207)
                     /locus_tag="RHX21_003059"
     CDS             complement(16025..16207)
                     /locus_tag="RHX21_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2158 domain-containing protein"
                     /protein_id="HDV1988212.1"
                     /translation="MSFMVSEEVTVKEGGPRMIVTGYSSGMVECRWYDGYGVKREAFH
                     ETELVPGEGSRSAEEV"
     gene            complement(16286..17203)
                     /locus_tag="RHX21_003060"
     CDS             complement(16286..17203)
                     /locus_tag="RHX21_003060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF808 domain-containing protein"
                     /protein_id="HDV1988213.1"
                     /translation="MLLAGSSLLTLLDDIATLLDDISVMGKLAAKKTAGVLGDDLSLN
                     AQQVSGVRANRELPVVWGVAKGSLINKVILVPLALIISAFIPWAITPLLMIGGAFLCF
                     EGVEKVLHMLEARKHKEDPAQSQQRLEKLAAQDPLKFEKDKIKGAIRTDFILSAEIVA
                     ITLGIVAEAPLLNQVLVLSGIALVVTVGVYGLVGVIVKIDDLGYWLAEKSSALMQALG
                     KGLLIIAPWLMKALSIVGTLAMFLVGGGIVVHGIAPLHHAIEHFAGQQSAVVAMILPT
                     VLNLILGFIIGGIVVLGVKAVAKMRGQAH"
     gene            17376..18296
                     /gene="yedA"
                     /locus_tag="RHX21_003061"
     CDS             17376..18296
                     /gene="yedA"
                     /locus_tag="RHX21_003061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="drug/metabolite exporter YedA"
                     /protein_id="HDV1988214.1"
                     /translation="MRFRQLLPLFGALFALYIIWGSTYFVIRIGVESWPPLMMAGVRF
                     LAAGILLLAFLLLRGHKLPPLRPLLNAALIGLLLLAVGNGMVTVAEHQNVPSGIAAVV
                     VATVPLFTLCFSRLFGIKTRKLEWVGIAIGLAGIIMLNSGGNLSGNPWGAILILIGSI
                     SWAFGSVYGSRITLPVGMMAGAIEMLAAGVVLMIASMIAGEKLTALPSLSGFLAVGYL
                     ALFGSIIAINAYMYLIRNVSPALATSYAYVNPVVAVLLGTGLGGETLSKIEWLALGVI
                     VFAVVLVTLGKYLFPANPVVAPVIQDASSE"
     gene            complement(18285..18755)
                     /gene="vsr"
                     /locus_tag="RHX21_003062"
     CDS             complement(18285..18755)
                     /gene="vsr"
                     /locus_tag="RHX21_003062"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VSPR family DNA mismatch endonuclease"
                     /protein_id="HDV1988215.1"
                     /translation="MGDVHDKATRSKNMRAIATRDTAIEKRLASLLTGQGLAFRVQDA
                     SLPGRPDFVVDEYRCVIFTHGCFWHHHHCYLFKVPATRTEFWLEKIGKNVERDRRDIS
                     RLQELGWRVLIVWECALRGREKLTDEALSERLEEWICGEGASAQIDTQGIHLLA"
     gene            complement(18736..20154)
                     /gene="dcm"
                     /locus_tag="RHX21_003063"
     CDS             complement(18736..20154)
                     /gene="dcm"
                     /locus_tag="RHX21_003063"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-cytosine methyltransferase"
                     /protein_id="HDV1988216.1"
                     /translation="MQENISVTDSYSTGNAAQAMLEKLLQIYDVKTLVAQLNGVGENH
                     WSAAILKRALANDSAWHRLSEKEFAHLQTLLPKPPAHHPHYAFRFIDLFAGIGGIRRG
                     FESIGGQCVFTSEWNKHAVRTYKANHYCDPATHHFNEDIRDITLSHKEGVSDEAAAEH
                     IRKHIPEHDVLLAGFPCQPFSLAGVSKKNSLGRAHGFACDTQGTLFFDVVRIIDARRP
                     AMFVLENVKNLKSHDQGKTFRIIMQTLDELGYDVADAEDNGPDDPKIIDGKHFLPQHR
                     ERIVLVGFRRDLNLKADFTLRDISECFPAQRVTLAQLLDPMVEAKYILTPVLWKYLYR
                     YAKKHQARGNGFGYGMVYPNNPQSVTRTLSARYYKDGAEILIDRGWDMATGEKDFDDP
                     LNQQHRPRRLTPRECARLMGFEAPGEAKFRIPVSDTQAYRQFGNSVVVPVFAAVAKLL
                     EPKIKQAVALRQQEAQHGRRSR"
     gene            complement(20221..20916)
                     /locus_tag="RHX21_003064"
     CDS             complement(20221..20916)
                     /locus_tag="RHX21_003064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HDV1988217.1"
                     /translation="MDLQHWQAQFENWLKNHHQHQDAAHDVCHFRRVWATAQKLAADD
                     DVDMLVILTACYFHDIVSLAKNHPQRQRSSILAAEETRRLLREEFVQFPAEKIEAVCH
                     AIAAHSFSAQIAPLTTEAKIVQDADRLEALGAIGLARVFAVSGALGVALFDGEDPLAQ
                     HRPLDDKRYALDHFQTKLLKLPQTMQTARGKQLAQHNAHFLVEFMAKLSAELAGENEG
                     VDHKVIDAFSSAG"
     gene            complement(20956..21321)
                     /locus_tag="RHX21_003065"
     CDS             complement(20956..21321)
                     /locus_tag="RHX21_003065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416472.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDV1988218.1"
                     /translation="MEKCDFYHIIVLSLNFPGYLKMEYGSTKMEERLSRSPGGKLALW
                     AFYTWCGYFVWAMARYIWVMSRIPDAPVSGFESDLGSTAGKWLGALVGFLFMALVGAL
                     LGSIAWYTRTRPARSRRYE"
BASE COUNT         5203 a         5678 c         5484 g         5073 t
ORIGIN      
        1 ctgtcttcac taattggtgt aaacttacca tttccaagac aactgactaa ctcacttgat
       61 aattcattta tgattgcatc atcagatact aactcatgtt gttttatcgt agattcagta
      121 ttagatgtga ctttatttaa ttgaaccgac tgagttttta acgaaagatc atttaatgga
      181 aacatttaca ctcctgttta ataaattata ttgcccaggg agcattctaa aacacaataa
      241 aattaccact atcaaaaatc gctcatatct atcgcccgga atatgaataa aaacatcaac
      301 aaagattaaa ttattcaaac gttactgttg cgtctgcggt cgtagcaaca tccgacgtgg
      361 tgatgagtgt taaaagagac actctgatgt tcagaggggt tatcgcgtat acggatcgtg
      421 gatggcagaa aactttcaga atcaggtttc cattttaaac cagaaattga gtgagtttgc
      481 cccatccatg ccccacacgg tgagatcgga tgtaattaac aacaggttac aaaacctaca
      541 cctgcatgct catcacttcc tgatacgccg ccaccagctt attacgcacc tgaatcccca
      601 tttgcataga aactgaggct ttttgcatat cggtcatcac atcgtttaac gccacgccgg
      661 gttcaccgag agtgaatttt tctgcctgcg tgcgggcagc tgtttgtgta tcactaatgc
      721 gatcgagcgc ggcgtgcagc tgcccggcaa aactaatggt cggttgcggc agtgattcct
      781 gcgcacgcgc actcatcgcc gtagcctgta actggctgat aaccccttca atcccctgta
      841 tcgctgacat tctcgtctcc cggataattt ctggtagcaa agcctaccag taagtcaata
      901 agacaaaggc gctaaataac aacaaaaaaa cgggtttatt ggcggataga aaaaaacgaa
      961 agcacaaata atgggagcgt caatttttcg agtttgctga cccgggagtg agtattgttc
     1021 cactttgcca ataacgctgt ccataatcag ccacgaggtg cgcgatgaat gcgactgcag
     1081 cccagacaaa atctcttgag tggcttaatc gcctgcgtgc gaatccgaaa attccattga
     1141 ttgttgccgg ttccgcggca gtggcggtca tggtcgcact gatcctgtgg gcgaaagccc
     1201 ccgactaccg cacattattc agcaatcttt ccgatcagga tggtggcgca attgtcagcc
     1261 aactgacgca aatgaatatt ccttaccgct tcagcgaagc cagcggcgct attgaagttc
     1321 cggcagataa agttcacgaa ctgcgtctgc gcctggcaca acaaggtttg cccaaaggcg
     1381 gcgcggtcgg tttcgaacta ctcgatcagg aaaagtttgg tatcagccag ttcagcgaac
     1441 aggtgaatta tcagcgggcg ctggaaggcg agctttctcg taccatcgaa actatcggcc
     1501 cggtaaaagg ggcgcgcgta catctggcaa tgccgaaacc gtctttattc gtccgtgaac
     1561 aaaaatcccc ttctgcatcg gtgacggtaa atctgttacc cggccgcgca ctcgatgaag
     1621 ggcaaattag cgccattgta catctggttt ccagcgcggt tgctggtctg ccgccgggga
     1681 acgtcacgct ggtggatcag ggtggacatc tgttaaccca gttcaacacc agcgggcgcg
     1741 atcttaatga cgctcagttg aaatatgcca gcgatgtcga agaccgtatt cagcggcgta
     1801 ttgaagcgat cctgtcgcct attgttggta acggtaatat tcacgcccag gtcacggcgc
     1861 agctggactt cgccagtaaa gaacaaacgg aagaacagta tcgccctaac ggtgatgaat
     1921 ctcatgcggc gcttcgttca cgccagctta atgagagcga gcaaagcggt tccggttatc
     1981 cgggcggcgt accgggggcg ttgtcgaatc aaccggcacc tgcgaataac gcgccaatca
     2041 gcacgcctcc ggcaaatcaa aataaccgcc agcagcaggc gagcaccacc agcaatagcg
     2101 ggccgcgtag cacacagcgg aatgaaacca gtaactacga agtcgatcgc accattcgtc
     2161 ataccaaaat gaacgtgggc gatgtgcaac gtctgtcagt cgcggtagtg gtgaattaca
     2221 aaaccttgcc agacggtaaa ccattgcctc tcagcaacga acagatgaag caaattgaag
     2281 atctgacccg cgaggcgatg ggcttttctg aaaaacgcgg tgactcgctc aatgtcgtta
     2341 actcgccgtt caatagcagt gacgaaagcg gcggagaact gccgttctgg caacagcaag
     2401 cgtttatcga tcagttgctg gctgccggtc gctggttgct ggtactgctg gtggcgtggc
     2461 tgctgtggcg gaaagcggta cgcccgcagt taacacgtcg cgccgaggcg atgaaagctg
     2521 tacagcaaca ggcgcaggcc cgtgaggaag tggaagatgc ggtggaagtc cgcctgagca
     2581 aagacgaaca actccaacaa cgacgcgcta accaacgtct gggggcagaa gtcatgagcc
     2641 agcgtatccg tgaaatgtct gataacgatc cgcgcgtggt ggcgctggtc attcgccagt
     2701 ggataaataa cgatcatgag taacctgaca ggcaccgata aaagcgtcat cctgctgatg
     2761 accattggcg aagaccgggc ggcagaggtg ttcaagcacc tctcccagcg cgaagtgcaa
     2821 acccttagcg ctgcaatggc gaacgtcacg cagatctcca acaagcagct aaccgatgtg
     2881 ctggcggaat ttgagcaaga agctgaacag tttgccgcac tgaatatcaa cgccaacgat
     2941 tatctgcgtt cggtattggt caaagctctg ggtgaggaac gtgccgccag cctgctggaa
     3001 gatattctcg aaactcgcga taccgccagc ggtattgaaa cgctcaactt tatggagccg
     3061 cagagcgccg ccgatctgat tcgcgatgag catccgcaaa ttatcgccac cattctggtg
     3121 catctgaagc gcgcccaggc cgccgatatt ctggcgttgt tcgatgaacg tctgcgccac
     3181 gacgtgatgt tgcgtatcgc cacctttggc ggcgtgcagc cagccgcgct ggcggagctg
     3241 accgaagtac tgaatggctt gctcgacggt cagaatctca agcgcagcaa aatgggcggc
     3301 gtgagaacgg cagccgaaat tatcaacctg atgaaaactc agcaggaaga agccgttatt
     3361 accgccgtgc gcgaattcga cggcgagctg gcgcagaaaa tcatcgacga gatgttcctg
     3421 ttcgagaatc tggtggatgt cgacgatcgc agcattcagc gtctgttgca ggaagtagat
     3481 tccgaatcgc tgttgatcgc gctgaaaggg gccgagcagc cactgcgcga gaaattcctg
     3541 cgcaatatgt cgcagcgtgc cgccgatatt ctgcgcgacg atctcgccaa ccgtggtccg
     3601 gtgcgtctgt cgcaggtgga aaacgaacag aaagcgattc tgctgattgt gcgccgcctt
     3661 gccgaaactg gcgagatggt aattggcagc ggcgaggata cctatgtctg ataatctgcc
     3721 gtggaaaacc tggacgccgg acgatctcgc gccaccacag gcagagtttg tgcccatggt
     3781 cgagccggaa gaaaccatca ttgaagaggc cgaacccagc cttgagcagc aactggcgca
     3841 actgcaaatg caggcccatg agcaaggtta tcaggcgggg attgccgaag gtcgccagca
     3901 aggtcatgag cagggctatc aggaaggact ggcccagggg ctggagcaag gtctggcaga
     3961 ggcgaagtct caacaagcgc caattcatgc ccggatgcag caactggtca gcgaatttca
     4021 aactaccctt gatgcacttg atagtgtgat tgcttcgcgc ctgatgcaga tggcgctgga
     4081 ggcggcacgt caggtcatcg gtcagacgcc aacagtggat aactcggcac tgatcaaaca
     4141 gatccaacag ttgttgcagc aagaaccgtt attcagcggt aaaccacagc tgcgcgtgca
     4201 cccggatgat ctgcaacgtg tggatgatat gctcggcgca accttaagtt tgcatggctg
     4261 gcgcttgcgg ggcgatccca cactccatcc tggcggctgt aaagtctccg ccgatgaagg
     4321 cgatctcgac gccagtgtcg ccactcgctg gcaagaactc tgccgtctgg cagcaccagg
     4381 agtggtgtaa tgaccacgcg cctgactcgc tggctaacca cgctggataa cttcgaagcc
     4441 aaaatggcgc agttgcctgc ggtacgtcgc tacgggcgat taacccgcgc taccgggctg
     4501 gtgctggaag ccaccggatt acaattgccg ctcggcgcaa cctgtgtcat tgagcgtcag
     4561 aacggcagcg aaacgcacga agtagaaagc gaagtcgttg gctttaacgg tcaacggctg
     4621 tttttaatgc cgctggagga agtggaaggt gtcctgcccg gcgcgcgggt ttatgccaaa
     4681 aacatttcgg ctgaaggact gcaaagcggc aagcagttgc cgctcggtcc ggcgttatta
     4741 ggtcgcgttc tggacggcag cggtaaaccg ctcgatggcc tcccctcccc cgatacgacg
     4801 gaaaccggtg cgctgattac cccaccattt aacccattgc aacgtacacc gattgaacat
     4861 gtgctggaca ccggcgtgcg cccaatcaat gccctgctta ccgtcgggcg cgggcagcgt
     4921 atgggactgt ttgccgggtc cggcgttggt aaaagtgtgc tgctggggat gatggcacgt
     4981 tacacccgcg ccgatgtcat tgtcgtgggt ttgattggtg aacgcggacg cgaagtaaaa
     5041 gattttattg agaatatcct cggtgccgaa gggcgtgcac gctccgtggt gattgccgct
     5101 ccggcggatg tttctcctct cctgcgaatg cagggtgccg cctatgccac gcgcattgcc
     5161 gaagattttc gcgatcgtgg tcagcatgtg ttgctgatta tggactccct cacccgctac
     5221 gcgatggccc agcgtgaaat tgcgctggcg attggcgaac cacccgccac taaaggttat
     5281 cccccgtcgg tgtttgccaa attaccggca ctggtcgagc gtgccggaaa tggcattagc
     5341 ggcggcggat cgattactgc attttatacc gtgctcactg aaggcgatga ccagcaggac
     5401 cccattgccg actctgcgcg ggcaatcctc gacggtcaca ttgtgctgtc tcgccgactg
     5461 gcggaagccg ggcactatcc ggctatcgat attgaagcgt cgatcagccg cgcaatgacg
     5521 gcgttgatca gtgagcaaca ttacgcgcga gtgcgcacct tcaaacagct gttgtcgagt
     5581 tttcagcgta accgcgatct ggttagcgtc ggcgcgtatg ccaaaggcag cgatccgatg
     5641 ctcgacaaag ccatcgccct gtggccgcag ctggagggct atttgcaaca aggcattttt
     5701 gaacgcgcgg actgggaagc gtctctccag gggctggagc gtattttccc gacagtgtca
     5761 taacccagga gataacggca gatggcagaa catggcgcgc tggcgaccct gaaagatctg
     5821 gcagaaaaag aggtagagga tgccgcgcgc ctgctgggtg aaatgcgtcg cgggtgtcag
     5881 caggcggaag aacagctcaa aatgctgatc gattatcaga atgaatatcg caataacctc
     5941 aacagcgata tgagtgccgg gatgaccagc aaccgctgga tcaactatca gcagtttatc
     6001 cagacgctgg aaaaagccat tactcagcat cgccagcaac ttaatcagtg gacgcagaaa
     6061 gttgacattg ccctgaacag ctggcgagaa aagaaacaac gtttgcaggc ctggcagaca
     6121 ctgcaggaac ggcaatccac ggcggcactg cttgcagaaa accgcctcga tcagaaaaag
     6181 atggatgagt tcgcccagcg cgccgccatg aggaaacctg aatgattcgc ttagcgccct
     6241 taattaccgc cgacgttgac accaccacat tgcctggcgg caaagccagc gatgctgcac
     6301 aagattttct cgcgttgttg agcgaagcat tagcaggcga gacaactacc gacaaagcgg
     6361 ccccccagtt gctggtggca acagataagc ccacgacaaa aggcgagccg ctggtcagcg
     6421 agattcttgc cgatgcgcaa caagcggatt tactgatccc tgtggatgaa acaccgcctg
     6481 tcatcaacga cgaacaatcc acatcaacac cattaaccac cgctcaaacg atgacgttgg
     6541 ctgcggtggc tggcaacaat acggcaaaag acgaaaaagc ggatgatctg aatgaagacg
     6601 tcaccgcaag cctgagcgcc ctttttgcga tgttgccggg ttttgacaat acgcccaaag
     6661 tgactgatgt gccgtcaacc gtgttaccgg cagagaaacc aacgctcttc acaaaactga
     6721 cttctgcgca actcacaaca gcacagcctg atgatgcccc cggcacgcca gctcagccat
     6781 taacaccgct ggtagcagaa gcccagagta aagcggaagt catcagcaca ccttcaccgg
     6841 tgaccgctgc cgccagcccg ctaatcactc cacaccagac acagccactg cccaccgtcg
     6901 ccgcgcctgt gttgagtgca ccgctgggtt ctcacgaatg gcaacaatca ttaagccagc
     6961 atatttcgct gttcacccgc caggggcaac aaagtgcaga gttgcgtctg cacccgcagg
     7021 atttaggtga agtgcaaatc tccctcaaag tggatgataa ccaggcgcaa atccagatgg
     7081 tttcaccgca tcaacacgta cgcgccgccc tggaagcagc gcttccggta ctgcgaacgc
     7141 agctggccga aagtggcatt cagttagggc aaagcaacat cagtggcgaa agctttagtg
     7201 gtcagcagca ggccgcttcc cagcaacagc aaagccaacg cacagcaaac catgaacctc
     7261 tggcggggga agacgacgat acgcttccgg ttcccgtctc tttacaagta cgtgtaacag
     7321 gcaacagcag cgttgatatt ttcgcctaac gtcagaggta gcaccgtaat ccgcgtcttt
     7381 tccccgcttt gttgcgctca agacgcagga taattagccg ataagcagta gcgacacagg
     7441 aagaccgcaa cacatgactg attacgcgat aagcaagaaa agcaagcgat cgctttggat
     7501 cccgattctg gtattcatta ccctcgcggc ctgtgccagc gcaggttaca gctactggca
     7561 ttcgcatcag gttgccgctg acgacaaagc gcagcaacgc gtcgtgccct ccccggtctt
     7621 ctatgcgctg gataccttta cggtcaatct gggcgatgca gatcgcgtac tttatatcgg
     7681 cataaccctg cgcctgaaag atgaagctac ccgctcgcgg ctgagtgagt atttgccgga
     7741 agtccgtagc cgtttgctgt tactgttttc gcgtcaggat gctgccgtac tggcgacaga
     7801 agaaggcaag aaaaacctga ttgccgagat taaaaccacg ctttccaccc cgcttgttgc
     7861 cgggcaaccg aaacaggatg tcaccgacgt gctgtatacc gcttttattc tgcgataacg
     7921 acatgggcga tagtattctt tctcaagctg aaattgatgc gctgttgaat ggtgacagcg
     7981 aagtcaaaga cgaaccgaca gccagtgtta gcggcgaaag tgacattcgt ccgtacgatc
     8041 cgaataccca acgacgggtt gtgcgcgaac gtttgcaggc gctggaaatc attaatgagc
     8101 gctttgcccg ccattttcgt atggggctgt tcaacctgct gcgtcgtagc ccggatataa
     8161 ccgtcggggc catccgcatt cagccgtacc atgaatttgc ccgcaacctg ccggtgccga
     8221 ccaacctgaa ccttatccat ctgaaaccgc tgcgcggcac agggctggtg gtgttttcac
     8281 cgagtctggt gtttatcgcc gtggataacc tgtttggcgg cgatggacgc ttcccgacca
     8341 aagtggaagg tcgcgagttt acccataccg aacagcgcgt catcaaccgc atgttaaagc
     8401 tggcgcttga aggctatagc gacgcctgga aggcgattaa tccgctggaa gttgagtacg
     8461 tgcgttcgga aatgcaggtg aaatttacca atatcaccac ctcgccgaac gacattgtgg
     8521 ttaacacgcc gttccatgtg gagattggca acctgaccgg cgaatttaat atctgtctgc
     8581 cattcagcat gatcgagccg ctacgggaat tgttggttaa cccgccgctg gaaaactcgc
     8641 gtaatgaaga tcagaactgg cgcgataacc tggtgcgcca ggtgcagcat tcacagttgg
     8701 agctggtcgc caactttgcc gatatctcgc tacgcctgtc gcagatttta aaactgaaac
     8761 ccgacgacgt cctgccgata gaaaaacccg atcgcatcat cgcccatgtt gacggcgtcc
     8821 cggtgctgac cagtcagtac ggcactctca acggtcagta tgcgttacgg atagaacatt
     8881 tgattaaccc gattttaaat tctctgaacg aggaacagcc caaatgagtg acatgaataa
     8941 tccggccgat gacaacaacg gcgcaatgga cgatctgtgg gctgaagcgt tgagcgaaca
     9001 aaaatcaacc agcagcaaaa gcgctgccga cgcggtgttc cagcaatttg gcggtggtga
     9061 tgtcagcgga acgttgcagg atatcgacct gataatggat attccggtca agctgaccgt
     9121 cgagctgggc cgtacgcgga tgaccatcaa agagctgttg cgtctgacgc aagggtccgt
     9181 cgtggcgctg gacggtctgg cgggcgaacc actggatatt ctgatcaacg gttatttaat
     9241 cgcccagggc gaagtggtgg tcgttgccga taaatatggc gtgcggatca ccgatatcat
     9301 tactccgtct gagcgaatgc gccgcctgag ccgttagtga tgaataacca cgctactgtg
     9361 caatcttccg cgccggtttc tgctgcgcca ctgctgcagg tgagcggcgc actcatcgcc
     9421 attattgccc tgatcctcgc tgctgcctgg ctggtaaaac ggctgggatt tgccccgaaa
     9481 cgcactggcg ttaatggtct gaaaattagc gccagtgctt cgctgggcgc gcgtgaacgg
     9541 gttgtggtgg tcgatgtgga agatgcacgg ctggtgctcg gcgttaccgc agggcaaatc
     9601 aatctgctgc ataaacttcc cccttcagca ccaacggaag agatacctca gaccgatttt
     9661 cagtcggtca tgaaaaactt gcttaagcgt agcgggagat cctgatgcgt cgtttgttgt
     9721 ctgtcgcccc tgtccttctc tggctggtta cgcccctcgc cttcgcgcaa ctgccaggta
     9781 tcaccagcca gccgctgcct ggcggtggac aaagctggtc gctcccggtg cagacgctgg
     9841 tgttcatcac ctcgttgacg tttattccgg caattttact aatgatgacc agtttcaccc
     9901 gcatcattat tgtttttggt ttattgcgta acgcgctggg aacgccctcc gcgccaccta
     9961 accaggtatt gctgggactg gcgctgtttt tgaccttttt tattatgtcg ccggtgatcg
    10021 ataaaattta tgtcgatgcg taccagccat tcagcgaaga gaaaatatca atgcaggagg
    10081 cgctggaaaa aggggcgcag ccgctgcgtg agtttatgct gcgtcagacc cgtgaggcgg
    10141 atttagggtt gtttgccaga ctggcgaata ccggcccgtt gcagggacct gaagccgtgc
    10201 cgatgcgcat tttgctcccg gcctacgtga ccagcgagtt gaaaaccgca tttcagatag
    10261 gcttcacgat tttcatccct tttttgatta tcgacctggt gattgccagc gtgttgatgg
    10321 cattggggat gatgatggtc ccccccgcca ccattgctct gccctttaaa ctgatgctgt
    10381 ttgtactggt ggatggttgg caattgctgg tcggttcgct ggcgcagagc ttttacagct
    10441 agagaggcaa aatgacacct gaatcggtca tgatgatggg gactgaagcg atgaaagtcg
    10501 cgctggcact agctgccccg ctgttgctgg tggcgctggt cacgggcctt atcatcagta
    10561 ttttgcaggc cgccacacag atcaacgaaa tgacgctgtc gtttatacca aaaatcatcg
    10621 ccgtatttat tgccattatt attgccggac cgtggatgct caatctgttg ctggattacg
    10681 tccgcacctt gttcactaac ctgccgtata tcatcgggta gcccgtacaa tgatgcaggt
    10741 gacaagcgat caatggcttt cctggttaag cctctacttc tggccgttac tgcgcgtgct
    10801 ggcgctcatt tctaccgcgc caattctgag cgaacgcagc gtgccgaaac gggtaaaact
    10861 gggtctggca atgatgatca cgttcgctat tgccccatca ttacctgcca acgatgttcc
    10921 tgttttttcg ttctttgctc tgtggctggc cgtgcagcag atcctgatcg gcgttgcgct
    10981 tggttttacc atgcaatttg cctttgccgc tgtgcgaacc gctggcgaaa ttatcggtct
    11041 gcaaatgggg ctgtcatttg cgacgtttgt cgatccagcc agccatctca atatgcccgt
    11101 tttagcgcgt atcatggata tgctggcgtt actgctgttc ctgacattta acggtcattt
    11161 atggttgatt tcactgctgg tcgatacctt tcacaccctg ccaattggtg gcgaaccgtt
    11221 gaacagcaat gcgtttctgg cactcaccaa agcggggagt ttgattttcc ttaacgggct
    11281 gatgctggcg ttaccgctca ttactctgct gctgaccctg aatctggcat taggtttact
    11341 gaatcgtatg gccccgcaat tatccatttt tgttattgga tttccattaa ctctgactgt
    11401 cggtatctct ttaatggcgg cattaatgcc gttaattgcg cctttttgcg aacatttatt
    11461 cagtgaaatt tttaatttgc tggctgatat tattagtgaa ttgccattaa tataattccg
    11521 taacgtttat catgttatcc taaggattat ccgaaaaata atacctgcga acatcttcca
    11581 ggatactcct gtggcgaaat atttgtttta agctcactca catatcgcaa catttacttt
    11641 actttaagac aattccaggc aaattataca acactttacg ggatagtaag tccgcctgaa
    11701 aaatcgcgag agtggcgcat taggtgaccc atgttgttcc gtttagtcat gatgaaatat
    11761 tcaggtaagg ggaattatcg ttacgcattg agtgagggta tgccatgtca acgattatta
    11821 tggatttatg tagttacacc cgactagatt taaccgggta tctgttgagt agaggggtta
    11881 aaaaaagaga aatcaacgac attgaaaccg ttgatgacct tgccatagct tgtgattcac
    11941 agcgcccttc agtggtgttt attaatgagg actgtttcat ccatgatgct tctaacagtc
    12001 agcgcatcaa gcacatcatt aatcaacatc ccaatacgtt atttatcgtt tttatggcaa
    12061 ttgccaatgt tcattttgat gaatatctat tggtcagaaa aaatttattg atcagttcta
    12121 aatcgattaa accggaatct ctcgacgata tccttggcga tattctgaaa aaagagacaa
    12181 cgataacctc ttttttaaat atgccgacgt tatcattgag ccgaaccgaa tcgagtatgt
    12241 tgcgaatgtg gatggcaggt cagggaacca ttcaaatctc tgaccaaatg aatatcaaag
    12301 ccaagaccgt ttcatcgcat aaaggtaata ttaaacgtaa gatcaaaacg cataataaac
    12361 aggttatcta ccatgtcgtc cgactgacgg ataatgtgac taatggtatt tttgtcaaca
    12421 tgcgctaaca cattctgact ggtggtttcc caccagtcag gctgaataag attactctgc
    12481 tttctccaca aagataccgt cctgatgccc tgcttcatta aagaaccaga tgccgagcgg
    12541 gtagtcttcc agcgaaacca ggtacattgt gccttcacta aactcctcaa ctgccagtac
    12601 cacgccagga cgacgcggac cgccatccgt tttgactgtt acccgatcat tcaccttcat
    12661 cgttttcctc ctgtggcttt gtgccagtgt agaacaattt cgtttttctg gcagcgccag
    12721 gcgcgcgcga gtgctgattt tctcgacggt ctatacttaa gagatgccag gcggacttaa
    12781 cgactggcgg caacaacaga gtaacggttg cgaggaaaga tgatgaaaac cgcaaaagag
    12841 tacagcgata ccgcaaaacg tgaggtcagc gtcgatgtcg atgccctgct ggcggcgatc
    12901 aatgaaatta gcgaaagcga agttcatcgc agccagaacg attctgaaca cgttagcgtc
    12961 gatggacgtg aatatcatac atggcgtgaa ttggcggatg ccttcgaact ggatattcat
    13021 gacttcagcg tctctgaagt gaatcgttga atgcacaata aaaaaatccc gaccctgagg
    13081 gggtcgggat gaaacttgct taagcaagaa gcacttaaaa aattcgttac accaggaaat
    13141 ctgatgtgtt catcacctta tccgcaattt ttttcgctga caagaaaata ttcgcgatat
    13201 gaatgattaa cgctacttat gaatagaaat gtgacgtgcg tcaccccttg gtggctctgg
    13261 cgtcaacggg atcgctcccg aaaaaatcat ctttgattat ttgtgctgtt ttgagaatca
    13321 tcctggtaag gggagaactg cgcgaccatg ttttcaattc aacaaccact actggttttt
    13381 agcgatcttg atggcaccct gctggacagt catagttatg actggcaacc ggctgccccc
    13441 tggctcagcc gtttacgcga agcgaatgtt cccgtcattc tctgtagcag taaaacttca
    13501 gcggaaatgc tgtacttgca aaaaacgttg gggctacaag ggttaccgct gattgccgaa
    13561 aatggcgcag tgatccagct tgctgaacaa tggcaggata tagacggttt tccacgcatc
    13621 atctcaggta ttagccatgg cgaaatcagc caggttttaa atacgctacg cgagaaagaa
    13681 cattttaaat tcacgacttt cgatgatgtc gacgatgcaa ccatcgccga atggacggga
    13741 ttaagccgta gccaggcggc gctgacgcag ctgcatgagg cgtcggtaac gctaatctgg
    13801 cgcgacagtg acgagcgtat ggcacaattt accgctcgtc tgaacgaact gggcttacag
    13861 tttatgcagg gtgcgcgctt ctggcacgta ctggatgcct ctgccggaaa agatcaggct
    13921 gccaactgga ttatcgcgac ctatcaacaa ttgtcaggca aacgcccaac cacacttggc
    13981 ctgggcgatg ggccaaacga tgcgccctta ctggaggtaa tggattacgc ggtgattgtg
    14041 aaagggctaa accgtgaagg ggtgcatctg catgatgagg atccggcccg cgtctggcga
    14101 acgcagcgtg aaggaccgga aggctggggt gaagggctgg accatttttt ctccgcccgt
    14161 taagcgttat cgctcgcgca tacccgatta cgcccggcct gtttagcgag ataaagtcga
    14221 cggtcagcca gtgactggag ttgttcaaaa tcataatcac cggtttcctc gctgctactt
    14281 acccccagcg aggcactgat gcgtatcgtc gtactcttag caatcaacat ctctttttca
    14341 tttaacttca ggcgaatacg ttctgcgact tccgcagcct ccgtcagact cgcgcctggc
    14401 agaatcacac aaaactcctc accaccgacc cgcccggcaa cgtcctgcgc acgcaaggaa
    14461 ctgctaatta atccggcagc atgagaaaga acacggtcgc ccgcctgatg accaaagcgg
    14521 tcattaatcg ctttaaaatg gtcaagatcg acctgaatga cagaaaaagg atgttggtgc
    14581 gtctgataca atttagcgag cggacgggct ttttcgaaca gtgcgccacg gttatataaa
    14641 cgcgttaagg tgtcgtgcca cgcctgccac tgcaacgagc tttgcagaac atacatgttg
    14701 ctaaccatcc ggcgaatcac ataccaggag atgagtaaca tggtggtaaa gagcgcccac
    14761 agcagggtta atgcaatgct gatactgccg aaatcgccgc gcacgccttc gcttaacgta
    14821 tggacgcgca ccagcacacc gtcgaaatgg tccagacgtt tccagctaac atagcgactg
    14881 tccatacgaa tgccgccccg cgtgtcatgt tccatcgcct gcgccagcaa ggccagttca
    14941 cgaggatcaa aaatattccc tgttggatgg tcaggattgg aagaggtcaa aaatctcagc
    15001 ttactgtcat agagctgata ctcaccatcg aggtttttat cgatggcgtt tcttaaaaat
    15061 tgctgcatgg tacgcacggg aatactcatc cccagcacgc cataccagta gttattactg
    15121 tctactggaa cactgacggt aacctgcggt tcagtattgc tggcgtgttc cggttgcgaa
    15181 gtaaaccagc gtactgcgcg gtgacgattt tctcgttgcg aatggccgat aaaccagggt
    15241 tgggtgacat agccgtaata acgcgttggt acattgcgcg taaacaaggt cggctgcgtc
    15301 gaaacgtaaa atccggcacg cgagacatac atcgcctgtt caaccatcga cgaggtgttg
    15361 tgcgccagtc gcagcaagta accaacttcc agtgcagcgg taatttcatt gtcgaggctt
    15421 tcatttacgc gagacaggag attcccctcg ctgactaatg catccgatac gccattgact
    15481 gacagggtgc gtcgtcggtt gagttcaatt tgccaggcgt gctcgtcgcg atgctgttcg
    15541 aactcggtta cagcattacg cagagaggtg aaatccagtg gcgctacgag agcttcgcgc
    15601 atgccattac gcaaaaagat cagtttgtcg acgttatact gcaaatgctt atcgagcgcg
    15661 ttggctacgt tttccagatg attacgctgg ctggagatat aggcatcttc cagcaccact
    15721 acttcacgcc aggtgagcaa ggtggaaaaa agcaatacca cgataaagca gagattaacg
    15781 acatgaccag gccccaggcg gcgtgcgagt tttttcaacc agctctggtt ttccattttt
    15841 gtctcgtgct gcaccctgac gactcccaac ctgctttttt atgattctgg cataacctgg
    15901 cgatagcgta ccgcaaaaca gcgataattt tataatggtg gcacgataag acgcgactat
    15961 cattcattgc cggcattggc acaccaggcc ggatgtgatc cggcctggtc ttaatgatac
    16021 cctttcaaac ttcttccgca gaacgactcc cctcccccgg aacaagctcg gtttcatgaa
    16081 aagcttcccg cttgaccccg taaccgtcat accaacgaca ctcaaccata ccgctggagt
    16141 atccagtgac aatcatccgc gggccgccct ctttaaccgt aacttcctca ctaaccataa
    16201 agctcatact cgcctccttt tttcgagtga aacttgttca ccttagttga agatggcgaa
    16261 ttttgcataa tagcctgtgc gagtattaat gtgcctgacc gcgcattttc gctacggctt
    16321 tcactcccag caccactatg ccgccgatga taaatccaag aatcagattt aaaacagtcg
    16381 gtaatatcat cgccaccact gcactttgct gcccggcgaa atgttcaatg gcgtgatgca
    16441 gcggcgcaat tccatgtacc acaatcccac cgccgacgag gaacatcgcc agcgtgccta
    16501 caattgataa cgctttcatc agccagggcg caatgatcaa taacccttta cctaatgcct
    16561 gcatcagcgc gctggatttt tccgccagcc aataccccag gtcatcaatc ttaacgataa
    16621 cccctaccag accgtagacg cccacggtca ctaccagcgc gatgcctgaa agcaccagca
    16681 cctgattaag caacggcgct tcggccacaa tccccagcgt gatggcgacg atttccgcag
    16741 acaatataaa atcggtacga atcgcccctt ttattttgtc cttttcaaac ttcagcggat
    16801 cctgcgccgc cagcttctcc agacgctgct gactctgcgc cggatcttct ttatgtttac
    16861 gcgcctccag catatgcagc actttctcta ccccttcaaa gcagagaaac gcgccgccaa
    16921 tcatcaacag tggcgtaatc gcccacggga taaacgcact gatgatcagc gccagcggca
    16981 ccagaatcac tttattgatc agcgatcctt tcgccacgcc ccagaccacg ggaagttccc
    17041 ggttggcccg cacgcctgaa acttgttgcg cattgagcga taagtcatcc cctaatacac
    17101 cggcggtttt cttcgccgcc agtttgccca tcacggagat atcgtccagt agagtggcga
    17161 tatcatcgag caacgtcagt aaactactcc cggccaaaag cattccctct catttttatt
    17221 gttgaagggt gtaagtatga agcaaaaacg gcagctctga tacttgcttc acaggtcaac
    17281 atttttttaa caatcaagtg caattatatc tctcgccagc agaatgattt tcacgtttac
    17341 tatgaaccac ctttttattt ccaccgtgag ggattatgcg tttccgccag ttgttaccgc
    17401 tttttggcgc gctgtttgcg ttgtatatca tttggggctc aacctatttt gtcattcgga
    17461 ttggcgtgga aagctggcct ccgttaatga tggcaggcgt tcgattcctg gcagccggta
    17521 ttttattgct ggcatttttg ctactgcgcg gacacaaact ccccccgcta cgtccgctgc
    17581 tcaatgccgc gctgattggc ctgttattgc tggctgtcgg taatggcatg gtgacggttg
    17641 ccgaacatca aaatgttcct tccggcatcg ccgccgtagt ggttgcaacc gtgcccctct
    17701 ttaccctgtg cttcagccgc ctgtttggca ttaaaacgcg caaactggaa tgggtgggta
    17761 ttgccattgg gcttgccgga atcatcatgc tcaatagcgg tggaaattta agcggcaatc
    17821 cgtggggcgc gattctgatt ttaatcggct cgattagctg ggcgtttggc tcggtttatg
    17881 gctcgcgcat taccttacct gtagggatga tggcgggtgc gattgagatg ctggcggcag
    17941 gcgtggtgtt aatgatcgcg tcgatgattg caggtgaaaa actgacggca ctcccttccc
    18001 tttcaggctt ccttgcggtc ggctatctgg cgctgtttgg ttcgattatc gccattaacg
    18061 cttatatgta tttaatccgc aacgtcagtc cggctctcgc caccagctac gcctacgtta
    18121 acccggtggt cgcggtcttg ctgggtacgg gactgggcgg agaaacgctg tcgaagattg
    18181 aatggctggc gctcggcgta attgtcttcg cggtggtact ggtcacgttg ggaaaatatc
    18241 tcttcccggc aaaccccgta gttgcgccag ttattcagga cgcatcaagc gagtaaatga
    18301 atcccctgcg tgtcgatctg cgcgctggca ccttcgccgc agatccactc ttccagacgc
    18361 tcgctaagcg cttcatccgt cagcttctcg cgcccacgta atgcacactc ccagacaatc
    18421 aatacgcgcc agccgagttc ctgcaaacga ctgatatcgc ggcgatcgcg ttcaacattt
    18481 ttacctatct tctccagcca gaactcggtt cgagtcgcag gcactttaaa cagatagcag
    18541 tgatgatgat gccagaagca gccgtgggta aatatcacgc agcgatattc atcaacgaca
    18601 aaatccgggc gtccgggcag actggcgtcc tgaacgcgaa atgccaggcc ctgcccggtt
    18661 aacagactgg cgaggcgctt ctctatcgcc gtatcacgcg tggcaatcgc gcgcatattt
    18721 ttgctgcgag tggccttatc gtgaacgtcg cccatgttgt gcctcttgct gacgcaacgc
    18781 caccgcctgt ttgatttttg gctcaagcag ttttgccacc gcggcaaaga ccggcacgac
    18841 caccgagtta ccgaactggc gataggcctg agtgtccgaa accggaatgc ggaatttcgc
    18901 ttctcccggc gcttcaaaac ccattaagcg cgcgcattcc cgaggcgtta accgacgtgg
    18961 acgatgttgc tgattcagcg gatcgtcaaa gtctttctca cccgtggcca tatcccagcc
    19021 gcgatcgatt aaaatttccg cgccatcttt gtaataacgc gcagacagcg tacgcgtgac
    19081 gctttgcgga ttgttaggat agaccattcc ataaccgaag ccgttaccgc gcgcctgatg
    19141 ttttttcgca taacgataga ggtacttcca cagcaccggc gtcaggatat atttcgcctc
    19201 gaccatcggg tccagcagtt gcgccagcgt cactcgctgt gcagggaaac attcgctgat
    19261 atcacgcaga gtaaaatcgg ctttcagatt aagatcgcga cgaaaaccca ccagcacgat
    19321 gcgttcacgg tgctgcggca gaaaatgttt accatcgatg attttcggat cgtccggccc
    19381 gttatcttct gcatcagcca cgtcatagcc cagttcgtcc agcgtctgca tgatgatgcg
    19441 gaacgtttta ccctggtcgt ggcttttcag gtttttgacg ttttcgagca caaacatcgc
    19501 cggacgacgc gcgtcgataa tgcgcaccac atcaaagaac agcgtgccct gagtatcgca
    19561 ggcaaaaccg tgcgcccgcc cgagcgagtt ctttttcgat acgccagcca gcgaaaatgg
    19621 ctgacaaggg aaaccggcca gtaaaacatc gtgttcagga atgtgtttac gaatatgttc
    19681 cgccgccgcc tcatcactca cgccttcttt atggctgagg gtgatgtcgc ggatatcttc
    19741 attaaaatga tgcgtcgccg ggtcgcaata atgattggct ttataagtgc gtaccgcatg
    19801 tttgttccat tcgctggtaa acacgcattg tccgccaatc gattcaaaac cgcgacggat
    19861 gccgccaatt ccggcaaata gatcgataaa gcgaaacgca taatgcggat gatgtgccgg
    19921 tggtttgggt aacaacgttt gcagatgggc gaactctttc tcacttaaac ggtgccatgc
    19981 cgagtcattc gccagcgcac gttttaaaat tgccgcgctc cagtgattct cacccacacc
    20041 attaagctgc gccaccagcg ttttaacatc ataaatttgc agcagtttct ccagcattgc
    20101 ctgtgcggca ttcccggtgc tgtatgaatc ggttactgat atattttcct gcatagattt
    20161 caccggccat ctgagatggc cgacaggtta acataattac agccatttag ggccacgcgc
    20221 tcagccagcg gatgaaaacg catctatcac cttgtgatcg acaccttcat tctcccccgc
    20281 cagttcggca ctgagcttcg ccataaactc gactaaaaaa tgcgcgttgt gctgcgccag
    20341 ctgcttgcct cttgcggttt gcatggtttg cggtagcttc agcaacttag tctggaaatg
    20401 atccagcgcg tagcgtttat catcaagcgg gcgatgctgt gcgagcggat cttcaccatc
    20461 aaacagcgcc acgcccaatg cccctgaaac ggcaaacacg cgcgccaggc caatcgctcc
    20521 cagggcttcc agccgatctg catcctggac gattttagct tccgtggtta agggggcgat
    20581 ttgcgcgctg aaactgtgag cggcaatggc atgacaaacg gcctcaattt tctccgccgg
    20641 aaattgcacg aactcttcac ggagcaggcg acgcgtctct tctgctgcca ggattgaaga
    20701 acgctgcctt tgcggatgat ttttcgccag gctcacaata tcgtgaaaat aacaggcggt
    20761 taaaatcacc agcatatcga cgtcgtcatc tgccgccagc ttctgtgccg tagcccagac
    20821 gcggcgaaaa tgacacacgt catgggccgc gtcctggtgc tgatgatggt ttttcaacca
    20881 gttttcgaac tgtgcctgcc agtgttgtaa gtccatacgc gctccgttgc caaagagtag
    20941 ccaccttagc agtttttatt catagcgtct gctacgtgcg ggacgagttc gggtgtacca
    21001 ggcaatgctg cctaacaatg ccccgaccag agccataaat aaaaatccga ccagtgcccc
    21061 taaccacttt cccgcggtag agcctaaatc gctttcaaat cccgacacgg gggcatcggg
    21121 gatccggctc atcacccaga tgtaacgcgc cattgcccag acgaaatagc cacaccatgt
    21181 ataaaaagcc cacaaagcca gtttgccacc agggctgcga gagagtctct cttccatctt
    21241 tgtcgaaccg tattccattt tgagataacc cggaaaattc agacttagta ctattatgtg
    21301 ataaaagtca catttttcca cattggatga gccagtcaag actcactcat tttttgaaca
    21361 aatagataat ttttgcgcaa cggcagtgaa tacaggaaaa atcgttttga gcgattttat
    21421 ttatctttga tatcggct
//
LOCUS       DAPGUL010000077        21157 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.078, whole genome shotgun sequence.
ACCESSION   DAPGUL010000077 DAPGUL010000000
VERSION     DAPGUL010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21157
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.078"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..1711
                     /locus_tag="RHX21_003066"
     CDS             <1..1711
                     /locus_tag="RHX21_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417981.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HDV1988219.1"
                     /translation="LPWIKLEKPDARLIRLSEKNNNWTFNLANDDNKDANAKPSAWSF
                     RLDNILFDQGRIAIDDKVSKADLEIFVDPLGKPLPFSEVTGSKGKADKEKVGDYVFGL
                     KAQGRYNGEPLTGTGKIGGMLALRGEGTPFPVQADFRSGNTRVAFDGVVNDPMKMGGV
                     DLRLKFSGDSLGDLYELTGVLLPDTPPFETDGRLVAKIDTEKSSVFDYRGFNGRIGDS
                     DIHGSLVYTTGKPRPKLEGDVESRQLRLADLGPLIGVDSGKGAEKSKRSEQKKGEKSV
                     QPAGKVLPYDRFETDKWDVMDADVRFKGRRIEHGSSLPISDLSTHIILKNADLRLQPL
                     KFGMAGGSIAANIHLEGDKKPMQGRADIQARRLKLKELMPDVELMQKTLGEMNGDAEL
                     RGSGNSVAALLGNSNGNLKLLMNDGLVSRNLMEIVGLNVGNYIVGAIFGDDEVRVNCA
                     AANLNIANGVARPQIFAFDTENALINVTGTASFASEQLDLTIDPESKGIRIITLRSPL
                     YVRGTFKNPQAGVKAGPLIARGAVAAALATLVTPAAALLALISPSEGEANQCRTILSQ
                     MKK"
     gene            complement(1945..3267)
                     /locus_tag="RHX21_003067"
     CDS             complement(1945..3267)
                     /locus_tag="RHX21_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter"
                     /protein_id="HDV1988220.1"
                     /translation="MQATATTLDHEQEYTPINSRNKVLVASLIGTAIEFFDFYIYATA
                     AVIVFPHIFFPQGDPTAATLQSLATFAIAFVARPIGSAVFGHFGDRVGRKATLVASLL
                     TMGISTVVIGLLPGYATIGIFAPLLLALARFGQGLGLGGEWGGAALLATENAPPRKRA
                     LYGSFPQLGAPIGFFFANGTFLLLSWLLTDEQFMSWGWRVPFIFSAVLVIIGLYVRVS
                     LHESPVFEKVAKAKKQVKIPLGTLLTKHVRVTVLGTFIMLATYTLFYIMTVYSMTFST
                     AAAPVGLGLPRNEVLWMLMMAVIGFGVMVPVAGLLADAFGRRKSMVIITTLIILFALF
                     AFNPLLGSGNPILVFAFLLLGLSLMGLTFGPMGALLPELFPTEVRYTGASFSYNVASI
                     LGASVAPYIAAWLQTNYGLGAVGLYLAAMAGLTLIALLLTHETRHQSL"
     gene            complement(3678..4691)
                     /gene="yhjD"
                     /locus_tag="RHX21_003068"
     CDS             complement(3678..4691)
                     /gene="yhjD"
                     /locus_tag="RHX21_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YhjD"
                     /protein_id="HDV1988221.1"
                     /translation="MTQENEIKRPTQDLEYEPIKQLDNSEKGGKVSQALETVTTTAEK
                     VQRQPVIAHLIRATERFNDRLGNQFGAAITYFSFLSMIPILMVSFAAGGFVLASHPML
                     LQDIFDKILQNISDPTLAATLKNTINTAVQQRTTVGLVGLAVALYSGINWMGNLREAI
                     RAQSRDVWERSPQDQEKFWVKYLRDFISLIGLLIALIVTLSITSVAGSAQQMIISALH
                     LNSIEWLKPTWRLIGLAISIFANYLLFFWIFWRLPRHRPRKKALIRGTFLAAIGFEVI
                     KIVMTYTLPSLMKSPSGAAFGSVLGLMAFFYFFARLTLFCAAWIATAEYKDDPRMPGK
                     TQP"
     gene            complement(4740..5639)
                     /locus_tag="RHX21_003069"
     CDS             complement(4740..5639)
                     /locus_tag="RHX21_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417978.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV1988222.1"
                     /translation="MDKIHAMQLFIKVAELESFSRAADFFALPKGSVSRQIQALEHQL
                     GTQLLQRTTRRVKLTPEGMTYYQRAKDVLSNLSELDGLFQQDATSISGKLRIDIPPGI
                     AKSLLLPRLSEFLYLHPGIELELSSHDRPVDILHDGFDCVIRTGALPEDGVIARPLGK
                     LTMVNCASPHYLTRFGYPQSPDDLTSHAIVRYTPHLGVHPLGFEVASVNGVQWFKSGG
                     MLTVNSSENYLAAGLAGLGIIQIPRIAVREALRAGRLIEVLPGYRAEPLSLSLVYPQR
                     RELSRRVNLFMQWLAGVMKEHLD"
     gene            6159..6761
                     /locus_tag="RHX21_003070"
     CDS             6159..6761
                     /locus_tag="RHX21_003070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDV1988223.1"
                     /translation="MQIVMFDRQSIFIHGMKISLQQRIPGVSIQGASQADELWQKLES
                     YPEALVMLDGDQDGEFCYWLLQKTVVQFPEVKVLITATDCNKRWLQEVIHFNVLAIVP
                     RDSTVETFALAVNSAAMGMMFLPGDWRTTPEKDIKDLKSLSARQREILTMLAAGESNK
                     EISRALNISTGTVKAHLESLYRRLEVKNRTQAAMMLNISS"
     gene            complement(6812..8461)
                     /locus_tag="RHX21_003071"
     CDS             complement(6812..8461)
                     /locus_tag="RHX21_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalase"
                     /protein_id="HDV1988224.1"
                     /translation="MLNQKIQNPNPDELMIEVDLCYELDPYELKLDEMIEAEPEPEMI
                     EGLPASDALTPADRYLELFEHVQSAKIFPDSKTFPDCAPKMDPLDILIRYRKVRRHRD
                     FDLRKFVENHFWLPEVYSSEYVSDPQNSLKEHIDQLWPVLTREPQDHIPWSSLLALPQ
                     SYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYY
                     LSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLIPNQAYRHVVRMP
                     DGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRD
                     TGRLASIRTTQFIPIDLNAFLFKLESAIANISALKGEKETEALFRQKASARRDAVNRY
                     LWDDENGIYRDYDWRREQLALFSAAAIVPLYVGMANHEQADRLANAVRSRLLTPGGIL
                     ASEYETGEQWDKPNGWAPLQWMAIQGFKMYGDDLLGDEIARSWLKTVNQFYLEQHKMI
                     EKYHIADGVPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP"
     gene            8866..10263
                     /gene="ccp"
                     /locus_tag="RHX21_003072"
     CDS             8866..10263
                     /gene="ccp"
                     /locus_tag="RHX21_003072"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c peroxidase"
                     /protein_id="HDV1988225.1"
                     /translation="MKMVSRITAIGLAGVAICYLGLSGYVWYHDNKRSKQADVQASAV
                     SENNKVLGFLREKGCDYCHTPSAELPAYYYIPGAKQLMDYDIKLGYKSFNLEAVRAAL
                     LADKPVSQSDLNKIEWVMQYETMPPTRYTALHWAGKVSDEERAEILAWIAKQRAEYYA
                     SNDTAPEHRNEPVQPIPQKLPTDAQKVALGFALYHDPRLSADSTISCAHCHALNAGGV
                     DGRKTSIGVGGAVGPINAPTVFNSVFNVEQFWDGRAATLQDQAGGPPLNPIEMASKSW
                     DEIIAKLEKDPQLKAQFLEVYPQGFSGENITDAIAEFEKTLITPDSPFDKWLRGDENA
                     LTAQQKKGYQLFKDNKCATCHGGIILGGRSFEPLGLKKDFNFGEITAADIGRMNVTKE
                     ERDKLRQKVPGLRNVALTAPYFHRGDVPTLDGAVKLMLRYQVGKELPQEDVDDIVAFL
                     HSLNGVYTPYMQDKQ"
     gene            10474..11874
                     /locus_tag="RHX21_003073"
     CDS             10474..11874
                     /locus_tag="RHX21_003073"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HDV1988226.1"
                     /translation="MDQKLLTDFRSELLDSRFGAKAISTIAESKRFPLHEMRDDVAFQ
                     IINDELYLDGNARQNLATFCQTWDDENVHKLMDLSINKNWIDKEEYPQSAAIDLRCVN
                     MVADLWHAPAPKNGQAVGTNTIGSSEACMLGGMAMKWRWRKRMEAAGKPTDKPNLVCG
                     PVQICWHKFARYWDVELREIPMRPGQLFMDPKRMIEACDENTIGVVPTFGVTYTGNYE
                     FPQPLHDALDKFQADTGIDIDMHIDAASGGFLAPFVAPDIVWDFRLPRVKSISASGHK
                     FGLAPLGCGWVIWRDEEALPQELVFNVDYLGGQIGTFAINFSRPAGQVIAQYYEFLRL
                     GREGYTKVQNASYQVAAYLADEIAKLGPYEFICTGRPDEGIPAVCFKLKDGEDPGYTL
                     YDLSERLRLRGWQVPAFTLGGEATDIVVMRIMCRRGFEMDFAELLLEDYKASLKYLSD
                     HPKLQGIAQQNSFKHT"
     gene            12244..13068
                     /gene="gadX"
                     /locus_tag="RHX21_003074"
     CDS             12244..13068
                     /gene="gadX"
                     /locus_tag="RHX21_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadX"
                     /protein_id="HDV1988227.1"
                     /translation="MQSLHGNCLIAYARHKYILTMVNGEYRYFNGGDLVFADASQIRV
                     DKCVENFVLVSRDTLSLFLPMLKEEALNLHAHKKISSLLVHHCSRDIPVFQEVAQLSQ
                     NKNLRYAEMLRKRALIFALLSVFLEDEHFIPLLLNVLQPNMRTRVCTVINNNIAHEWT
                     LARIASELLMSPSLLKKKLREEETSYSQLLTECRMQRALQLIVIHGFSIKRVAVSCGY
                     HSVSYFIYVFRNYYGMTPTEYQERSAQGLPNRDSAASIVAQGNFYGTDRSAEGIRL"
     gene            13436..14164
                     /gene="gadW"
                     /locus_tag="RHX21_003075"
     CDS             13436..14164
                     /gene="gadW"
                     /locus_tag="RHX21_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadW"
                     /protein_id="HDV1988228.1"
                     /translation="MTHVCSVILIRRSFDIYHEQHKISLHNESIVLLEKNLADDFAFC
                     SPDTRRLDIDELTVCHYLQNIRQLPRNLGLHSKDRLLINQSPPMPLVTAIFDSFNESG
                     VNSPILSNMLYLSCLSMFSHKKELIPLLFNSISTVSGKVERLISFDIAKRWYLRDIAE
                     RMYTSESLIKKKLQDENTCFSKILLASRMSMARRLLELRQIPLHTIAEKCGYSSTSYF
                     INTFRQYYGVTPHQFAQHSPGTFS"
     gene            complement(14527..17640)
                     /locus_tag="RHX21_003076"
     CDS             complement(14527..17640)
                     /locus_tag="RHX21_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="HDV1988229.1"
                     /translation="MANYFIDRPVFAWVLAIIMMLAGGLAIMNLPVAQYPQIAPPTIT
                     VSATYPGADAQTVEDSVTQVIEQNMNGLDGLMYMSSTSDAAGNASITLTFETGTSPDI
                     AQVQVQNKLQLAMPSLPEAVQQQGISVDKSSSNILMVAAFISDNGSLNQYDIADYVAS
                     NIKDPLSRTAGVGSVQLFGSEYAMRIWLDPQKLNKYNLVPSDVISQIKVQNNQISGGQ
                     LGGMPQAADQQLNASIIVQTRLQTPEEFGKILLKVQQDGSQVLLRDVARVELGAEDYS
                     TVARYNGKPAAGIAIKLATGANALDTSRAVKEELNRLSAYFPASLKTVYPYDTTPFIE
                     ISIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVIAEDKLPPKEATHKSMGQIQRALVGIAVVLS
                     AVFMPMAFMSGATGEIYRQFSITLISSMLLSVFVAMSLTPALCATILKAAPEGGHKPN
                     ALFARFNTLFEKSTQHYTDSTRSLLRCTGRYMVVYLLICAGMAVLFLRTPTSFLPEED
                     QGVFMTTAQLPSGATMVNTTKVLQQVTDYYLTKEKDNVQSVFTVGGFGFSGQGQNNGL
                     AFISLKPWSERVGEENSVTAIIQRAMIALSSINKAVVFPFNLPAVAELGTASGFDMEL
                     LDNGNLGHEKLTQARNELLSLAAQSPDQVTGVRPNGLEDTPMFKVNVNAAKAEAMGVA
                     LSDINQTISTAFGSSYVNDFLNQGRVKKVYVQAGTPFRMLPDNINQWYVRNASGTMAP
                     LSAYSSTEWTYGSPRLERYNGIPSMEILGEAAAGKSTGDAMKFMADLVAKLPAGVGYS
                     WTGLSYQEALSSNQAPALYAISLVVVFLALAALYESWSIPFSVMLVVPLGVVGALLAT
                     DLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAVEMMQKEGKTPIEAIIEAARMRLRP
                     ILMTSLAFILGVLPLVISHGAGSGAQNAVGTGVMGGMFAATVLAIYFVPVFFVVVEHL
                     FARFKKA"
     gene            complement(17665..18822)
                     /gene="mdtE"
                     /locus_tag="RHX21_003077"
     CDS             complement(17665..18822)
                     /gene="mdtE"
                     /locus_tag="RHX21_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter subunit MdtE"
                     /protein_id="HDV1988230.1"
                     /translation="MNRRRKLLIPLLFCGAMLTACDDKSAENAAAMTPEVGVVTLSPG
                     SVNVLSELPGRTVPYEVAEIRPQVGGIIIKRNFIEGDKVNQGDSLYQIDPAPLQAELN
                     SAKGSLAKALSTASNARITFNRQASLLKTNYVSRQDYDTARTQLNEAEANVTVAKAAV
                     EQATINLQYANVTSPITGVSGKSSVTVGALVTANQADSLVTVQRLDPIYVDLTQSVQD
                     FLRMKEEVASGQIKQVQGSTPVQLNLENGKRYSQTGTLKFSDPTVDETTGSVTLRAIF
                     PNPNGDLLPGMYVTALVDEGSRQNVLLVPQEGVTHNAQGKATALILDKDDVVQLREIE
                     ASKAIGDQWVVTSGLQAGDRVIVSGLQRIRPGIKARAISSSQENASTESKQ"
     gene            18882..19160
                     /locus_tag="RHX21_003078"
     CDS             18882..19160
                     /locus_tag="RHX21_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988231.1"
                     /translation="MRDLQTSGIVGLSASKVGYRYSDRHGEVNDKKNVAVLPTVPASI
                     RATKGSTGGYTYQGNKVVLASPLVITGGNEISICIPRHASHQFQLLMS"
     gene            complement(19161..19688)
                     /gene="gadE"
                     /locus_tag="RHX21_003079"
     CDS             complement(19161..19688)
                     /gene="gadE"
                     /locus_tag="RHX21_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadE"
                     /protein_id="HDV1988232.1"
                     /translation="MIFLMTKDSFLLQGFWQLKDNHEMIKINSLSEIKKVGNKPFKVI
                     IDTYHNHILDEEAIKFLEKLDAERIIVLAPYHISKLKAKAPIYFVSRKESIKNLLEIT
                     YGKHLPHKNSQLCFSHNQFKIMQLILKNKNESNITSTLNISQQTLKIQKFNIMYKLKL
                     RRMSDIVTLGITSYF"
     gene            complement(20487..21059)
                     /gene="hdeD"
                     /locus_tag="RHX21_003080"
     CDS             complement(20487..21059)
                     /gene="hdeD"
                     /locus_tag="RHX21_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-resistance protein HdeD"
                     /protein_id="HDV1988233.1"
                     /translation="MLYIDKATILKFDLEMLKKHRRAIQFIAVLLFIVGLLCISFPFV
                     SGDILSTVVGALLICSGIALIVGLFSNRSHNFWPVLSGFLVAVAYLLIGYFFIRAPEL
                     GIFAIAAFIAGLFCVAGVIRLMSWYRQRSMKGSWLQLVIGVLDIVIAWIFLGATPMVS
                     VTLVSTLVGIELIFSAASLFSFASLFVKQQ"
BASE COUNT         5479 a         5005 c         5315 g         5358 t
ORIGIN      
        1 gctgccgtgg atcaagctcg aaaagcccga cgcgcgcctg attcgcctct ccgaaaagaa
       61 caataactgg acgtttaatc tcgccaacga tgataacaaa gacgcgaatg caaagccgtc
      121 ggcatggtcg tttcggctgg ataatattct tttcgatcaa gggcggatcg ccattgatga
      181 caaagtaagc aaagcggatc tggagatttt tgttgatccg ttaggtaagc cgctgccgtt
      241 cagcgaagtt actggatcga aaggtaaagc ggataaagaa aaggtgggcg attacgtttt
      301 tggcctgaag gcgcagggac gttataacgg tgaaccgctc acgggtacgg gaaaaatagg
      361 cggtatgctg gcgctgcgtg gcgaagggac gccgtttccg gtacaggctg atttccgctc
      421 tggtaacacc cgtgttgctt ttgatggcgt cgtgaatgac ccaatgaaga tgggcggtgt
      481 cgatttacgg cttaaatttt ctggcgattc actgggtgat ctctatgaac tgacgggcgt
      541 tctgctgccc gataccccgc cgtttgaaac ggatggtcgg ctggtagcga aaatcgacac
      601 tgaaaaatcg tcggtctttg attatcgcgg ttttaatggg cgaattggcg atagcgatat
      661 ccacggttct ctggtctaca ccaccggaaa gccacgacca aaactggaag gtgatgtcga
      721 gtcgcggcaa ttgcggctgg cggacctggg accgttaatt ggcgttgact ccgggaaagg
      781 ggcagaaaag tcgaaacggt ctgaacagaa gaagggcgaa aaaagcgttc agcctgcggg
      841 caaagtgctg ccttatgacc gcttcgaaac cgataaatgg gacgttatgg atgccgatgt
      901 tcgcttcaaa gggcggcgca ttgagcatgg cagtagcctg ccgattagcg atctttctac
      961 tcatatcatc ctcaaaaatg ctgacctgcg cctgcaaccg ctgaaatttg gcatggcggg
     1021 cggcagcatt gcggcgaata tccatctgga aggcgataaa aagccgatgc aggggcgggc
     1081 agatattcag gctcgtcgac tgaaactgaa agaactgatg cccgatgtgg aactgatgca
     1141 gaagacgctg ggggaaatga acggtgacgc ggaactacgc ggtagcggta actcggtggc
     1201 ggcgctttta ggcaacagta acggcaacct gaaactgttg atgaatgacg ggctggtgag
     1261 ccgcaacctg atggagattg ttgggctgaa tgtcggcaac tacattgtcg gtgcgatatt
     1321 tggtgacgat gaggtgcggg tgaactgcgc ggcggcgaat ctgaatattg ccaacggcgt
     1381 ggcgcgcccg cagatttttg ctttcgatac tgagaacgcg ttgattaatg ttaccggcac
     1441 ggcaagtttt gcttcggaac agctggattt gactattgat ccggagagta aagggattcg
     1501 gattatcaca ctgcgttcgc cgctgtatgt gcgtgggacg tttaaaaatc cgcaggctgg
     1561 ggtgaaagcc gggccgttga ttgcccgtgg tgctgttgct gcggcactgg caacgctggt
     1621 aacaccggcg gcggcgttac tggcactgat ctcaccttcc gaaggggagg ctaatcagtg
     1681 tcggacgata ttgtcgcaga tgaagaagtg atgaggttgg attgtgtttg ctggtgagtt
     1741 cgggagcagc gtgttcccct caccctaacc ctctccccaa aggggcgagg ggactgtttt
     1801 gtgcgtgttg aaacaacgag taccgctttt ccgttcactt tctgggggag ggctgttatg
     1861 ttcgcgatat aacatctcgc tccgcttttc tccctctccc tttcagggag agggctgggg
     1921 tgagggtggc tgcccacacg atacttacaa cgactgatgt cgcgtctcat gggtcagcag
     1981 cagggcgatt aacgtcaagc cagccatcgc cgccagatat aaccccaccg cacctaaccc
     2041 gtagttagtc tgcaaccagg ctgcgatata cggcgcaacg gaagccccga gaatcgacgc
     2101 tacgttgtaa gagaacgatg ctccggtgta acgcacttct gttgggaaca gctctggtaa
     2161 cagcgcgccc atcggcccga aggtcagccc catcagactt aaccccagca gcaggaaggc
     2221 aaaaaccaga atcgggttgc cagaaccgag cagcgggtta aaggcgaaca gcgcgaacag
     2281 gatgatcagc gtggtgataa ttaccatgct tttacggcga ccaaaggcat cagccagtaa
     2341 tccggcgact ggcaccatca cgccaaaacc aataactgcc atcatcagca tccacaacac
     2401 ttcgttacgt ggcaggccaa gcccaactgg cgcggcggcg gtactgaagg tcatagagta
     2461 gaccgtcatg atgtaaaaca gcgtatatgt tgccagcatg atgaacgtac ccagtacggt
     2521 tacgcgaaca tgtttggtca gcagcgtacc cagcgggatc ttcacctgtt ttttcgcttt
     2581 agcgactttc tcaaacaccg gcgactcatg cagcgacacg cgaacataca ggccgataat
     2641 gaccagcacc gccgagaaga taaatggcac acgccagccc cagctcataa actgctcgtc
     2701 ggtcagtagc caggaaagca gcaagaaagt gccgttggca aagaagaagc caatcggtgc
     2761 gcccagctgt gggaaggagc catacagtgc acgtttgcgc ggtggggcgt tttcagtcgc
     2821 cagcagcgcc gcgccgcccc attcaccgcc taagcccaga ccctgaccaa atcgagccag
     2881 cgccagcagc agcggggcga aaataccaat cgtggcatag cccggcagca gaccaatcac
     2941 cacggtcgaa atccccatcg ttagcaacga ggcgaccagc gtcgctttac gcccaacgcg
     3001 atcgccaaaa tgaccaaaaa cggcagagcc aatggggcgc gcgacgaagg cgatggcgaa
     3061 ggtggcgagc gactgtagcg ttgctgccgt tggatcgccc tgcgggaaga agatatgcgg
     3121 aaacacaata acggccgcag tggcgtaaat gtaaaagtcg aagaactcaa tggccgtgcc
     3181 aatgagagag gcgacaagga ctttattacg cgagttgatt ggcgtgtatt cttgctcgtg
     3241 gtcgagtgtt gtggctgttg cttgcataat cttttcttat tttttggcta acgaatagcc
     3301 atattacgca cagcaaaagt gatatttcaa tgtgtaacaa atcgcggaaa tggtcaaaaa
     3361 ccaggcaaaa aggggataat gtttaggcca gtgatttttc ttctatgaaa tgcttcacat
     3421 aattttataa atagtggata aaactggttt caggttaaat aaaagttacc aactggattt
     3481 atatgctggg gttatgagtt ggaatgaaat tgtttgctcc caaatagatg gctgaagagg
     3541 ctctggggaa gagtttcaag aggttatgtg cgcattatag ccggatgcga tgctggcgca
     3601 tcttatccgg cctacgggga gccaggccga ataaaatcgt atgccggata aggcgtttac
     3661 gccgcatccg gcctatttta aggctgcgtt ttccctggca ttcgcgggtc gtctttatat
     3721 tcggcggtgg caatccacgc cgcgcaaaac agcgtcaaac gggcgaagaa gtagaaaaat
     3781 gccatcagcc ccagcacgga accaaatgct gcgccagagg gggatttcat cagcgatggc
     3841 agggtgtagg tcatcacgat tttaatcact tcaaaaccaa tagcagccag aaatgttccg
     3901 cgaatcaggg cttttttgcg cggacggtgg cgcggtaacc gccagaagat ccagaagaaa
     3961 agcagatagt tggcgaagat ggaaatcgcc aggccaatca accgccacgt cggtttcagc
     4021 cactcaatgc tgttcaggtg cagggcgcta ataatcattt gctgcgccga accggcaacc
     4081 gaggtgatcg aaagcgtcac aatcagcgca atcaacaaac caatcagcga aataaaatca
     4141 cgcagatatt ttacccagaa cttctcctga tcttgcggcg agcgttccca gacatcgcgc
     4201 gactgggcac gaatcgcttc acgcaggtta cccatccagt tgatgccgga ataaagcgcc
     4261 accgccaggc cgacaagccc tacagtcgta cgctgctgaa cggcggtgtt gatggtgttt
     4321 ttcaacgtgg cggctagcgt cggatcgctg atgttttgca gaattttgtc gaagatatcc
     4381 tgtagcaaca tcggatggga ggccagcaca aagccccctg cggcaaacga caccatcaaa
     4441 atcgggatca tcgataaaaa tgagaaatag gtgatagccg caccaaactg gttacccagc
     4501 cgatcgttaa agcgttctgt cgcgcgaatc aggtgcgcaa taaccggttg gcgttggact
     4561 ttttcggcag tggtggtgac ggtttccagc gcctggctaa ctttgccgcc tttctcgcta
     4621 ttatccaact gcttaatcgg ctcgtactcc agatcctggg tgggacgttt gatctcgttt
     4681 tcctgcgtca tccgctcttt tgtccttctg tcgtggtcat tcttaaaaag tatagtcggt
     4741 cagtccaggt gctctttcat tacgccagcc agccactgca taaacaggtt tacacgccgg
     4801 gaaagctccc gacgctgcgg gtaaaccagc gaaagggaga gcggctcggc acggtagcct
     4861 ggcaacactt caataaggcg cccggcacgc agggcttcgc gcacggcaat gcgcgggatc
     4921 tgaataatcc ccagaccggc aagaccggcg gcgagatagt tttcgctact atttaccgtc
     4981 aacatgccgc cagacttaaa ccactggacg ccattaacgc tggcaacctc aaaacctaac
     5041 ggatgtacac ccaggtgcgg tgtataacgc actattgcgt gtgaagtcag atcatcgggg
     5101 ctttgcggat aaccaaagcg cgtcagatag tgcggactgg cacagttgac catggtcagt
     5161 ttgccgaggg gacgggcgat aacgccatct tccggtaacg cgccagtgcg tatcacgcaa
     5221 tcaaaaccat catgaagaat atctaccgga cggtcatggc tactcagttc cagctcaatt
     5281 cccggatgca gatagagaaa ttccgacagg cgcggcagta acaggctttt cgcgattcct
     5341 ggcgggatgt cgatgcgtaa tttaccgctg atactggtgg catcctgttg aaacagaccg
     5401 tccagttcgc tgagattact caacacatct tttgctcgtt gataataggt catgccttct
     5461 ggcgtgagtt tgacccgtcg cgtggtgcgc tggagaagct gggtgccaag ttgatgttcc
     5521 agtgcctgta tctggcgcga aacacttcct tttggcaaag caaagaaatc cgccgcgcgg
     5581 gaaaaacttt ccagctccgc gactttgatg aacaactgca ttgcgtgaat tttatccatt
     5641 tctttgaccg attgttgttc acagcgaaac agtaacgcgc atatcgcatt gtttattgtt
     5701 ttttctaaca tctaatgccg ggtttcacaa tgttgtcatg acgaatgtgg cgatttctca
     5761 gcaggaaaag ggcggaatag ctttctgaga aaggtgaatc cccctaaaca gagcgtattt
     5821 ttcagcgatt ccctttaaag tgaatagagg acgtgttggc tatttgtgct tatttttgtc
     5881 tcattgccgt ttgttatttt tgcttgtggt cgcggagttt catttttaat tgcatgcgta
     5941 ctaaccacca atataaggaa atcctcaaaa ttgttttaaa tagtgccctc gacatgtaat
     6001 ttcaggcgtt tagctgtaac tatttatatc ggtaactatt ttctacgcgt catctctgta
     6061 gaatggccac cgccaaatgg cgaattctta ttttttctcg cgggtaatac ccttccacta
     6121 cttaagtctt tttaacgtat tcaggtggag attcagttat gcaaatagtc atgtttgaca
     6181 ggcagtcaat atttattcat ggaatgaaaa tcagtttaca gcagcgtatt ccaggagtga
     6241 gtattcaggg ggccagtcag gcagacgagt tatggcaaaa gctggaaagt taccctgaag
     6301 ccttagttat gctcgatggc gatcaggatg gtgagttttg ctactggttg ctgcaaaaaa
     6361 ccgtggtgca gtttcctgag gttaaggtgt taatcacggc gacggattgc aataaacggt
     6421 ggttacagga agttattcat tttaatgtgc tggccattgt gcctcgtgat tcaaccgtcg
     6481 agacatttgc gttggcggta aatagtgcgg cgatggggat gatgtttctg cctggagact
     6541 ggcggacgac gccggaaaag gacattaaag atctcaaatc gttaagcgcc cgccagcggg
     6601 agattttaac catgttagcg gcgggcgaat caaataagga gatcagcaga gcgctgaata
     6661 tcagtaccgg aacggtaaaa gcgcatctgg aatccctgta tcgccgtctg gaagtgaaaa
     6721 atcgcaccca ggcggcaatg atgttaaata tctcctcctg aagaggataa ttttacagcc
     6781 agcaggaagt tagcggctgg ctgtaaaaat attatggttc gccgtacaaa ccaattaaac
     6841 ggcgtaccac accgttagtc cagccaaacc catcctgcaa cggatactcg ccaccgccgc
     6901 cttcgcgggg aacaccatcg gcaatatggt atttctcgat cattttgtgc tgttccagat
     6961 agaactgatt caccgttttc agccagctgc gcgcgatttc atcacccaga aggtcatcgc
     7021 catacatttt aaatccctga attgccatcc attgtaacgg tgcccagcca ttgggtttat
     7081 cccactgttc accggtttcg tactcgcttg ccagaatccc gccaggtgtc agtaaccggc
     7141 tgcgtacggc gtttgccaga cgatcggcct gttcatggtt cgccatgccg acatagagcg
     7201 gcacaatggc ggcagcggaa aacagcgcca gttgttcgcg tcgccagtcg taatcgcggt
     7261 agatgccgtt ttcatcatcc cagaggtaac ggtttaccgc atcgcgacgg gcactggcct
     7321 tctggcggaa cagcgcttct gtctctttct cgcctttcag cgccgagatg ttggcgatgg
     7381 cgctctccag tttaaacagg aaggcattca gatcgatggg gatgaactgg gtggtacgaa
     7441 tgctcgccag acgaccagta tcacgcagcc aacgggaaga gtaatcccaa cctgaggccg
     7501 ctcccgcgcg taaatcgcgg tacacctcgt tgggcgggcg accagaatgt ttcgcggttt
     7561 caacgtcctc aagccaggat tcgtcacgcg gcgtgtcgcg atcgtcccaa taacggttga
     7621 gcagcgatcc gtccggcatc cgcacaacat ggcgataggc ctgattaggg atcaacgatt
     7681 ctgcaccgtc catccagaag gcatattcca ttttaaggtg gtcgagatag cggcgcgcac
     7741 cgcgtacacc atcttcttca aacaactcca ccatcagcgc aaaaaccggt ggttgcgatc
     7801 ggctcaaata ataggtgcgg ttgccgttgg ggatgtgacc atagttttcg atcatccagg
     7861 cgaagttatc ggccatgcat ttcagcaaat cttcccgacc actttccgcc agccccagca
     7921 tggtgaaata ggaatcccaa tagtaggttt cgctaaaacg gccgcccggg acaatatatg
     7981 actgcggtag cgccagcaga gaagaccacg gaatgtgatc ctgtggttcg cgggttagca
     8041 ccggccacag ctggtcgata tgctctttca gggaattttg cgggtccgat acatactcgc
     8101 tggagtagac ctccggcagc cagaagtgat tttcaacaaa cttgcgcaag tcaaaatcac
     8161 gatgacggcg cactttacgg tagcggatta aaatatccag cgggtccatt ttgggtgcgc
     8221 agtcgggaaa ggttttactg tcggggaaaa ttttcgccga ctgaacatgc tcgaacagtt
     8281 cgagatagcg atcggcaggc gtcagcgcat cagaggcggg cagcccttca atcatctcgg
     8341 gttccggttc tgcctcgatc atctcatcca gttttaattc atacgggtcc agctcatagc
     8401 agagatcgac ttcgatcatc agttcgtctg gattagggtt ttgaattttc tgattgagca
     8461 taaggatcca acctccgaaa ttcgtcgcta attatcgggc ttttctttaa gggtagtcat
     8521 tcgctccgcc tggtgggcga caaagcgtgc ggtggatcac gtttattaac ctgtcaaaaa
     8581 atataacgca ctaatatcca tggaatttat aaaaatacgg atttcgtgtt gtttttcatt
     8641 ttcagaacat tcaatcctgc tctcgccgca atcatgatat gccattcctg atctgggtaa
     8701 taggcacagg ctatcttatt gatagtttat attcatgtaa ttgattgatt cctatcaaaa
     8761 agcgtatctc cctgtttttt atgatggctt tgtctcgcag agacgtttgc agcattctgg
     8821 aaaattttct gggtcacaat aactcaccac cgtgagggaa gaataatgaa aatggtctca
     8881 cgtattaccg cgatcggcct ggctggcgtc gcgatttgct atttagggtt atctggttat
     8941 gtgtggtacc acgataataa acgcagtaaa caggccgatg ttcaggcatc tgctgtcagt
     9001 gaaaataata aggttttagg ctttctccgc gaaaaaggat gcgactattg ccacacacct
     9061 tcggcagaat tacccgccta ttattatatt cctggcgcga aacagttgat ggattacgac
     9121 attaagcttg gatataaatc ttttaacctc gaggccgtgc gtgcggcact gctggctgat
     9181 aaacccgttt cgcaaagcga tctgaataag attgaatggg tgatgcagta tgaaactatg
     9241 ccaccaacgc gttataccgc gctacactgg gcgggtaagg tgagtgatga agagcgggcg
     9301 gaaatactgg cctggattgc aaaacagcgc gcggaatatt acgccagcaa tgatactgct
     9361 ccggagcatc gcaatgaacc ggtgcagccc atcccgcaaa aactgcctac cgatgcgcaa
     9421 aaagtggcgt tgggctttgc gctgtatcac gatccccgtt tatcggctga tagcaccatt
     9481 tcatgcgctc attgccatgc gttgaatgcg gggggcgtcg atggcagaaa aacatcgatt
     9541 ggtgttggtg gcgcagttgg gccgattaac gcgccgacgg tatttaactc agtatttaac
     9601 gttgagcagt tctgggatgg tcgtgcggca acattgcagg atcaggcagg tggaccgccg
     9661 ttgaacccga ttgaaatggc gtcgaaatcc tgggacgaaa ttattgctaa gctggaaaaa
     9721 gatccgcagc ttaaagcgca gttcctcgaa gtttatccgc aaggtttcag tggcgaaaat
     9781 attactgatg ccattgctga atttgagaaa acattaatta cgccggattc cccatttgat
     9841 aaatggttgc gtggagatga aaatgcgctg acggcgcaac agaaaaaagg ctatcaatta
     9901 tttaaagata ataaatgtgc aacttgtcat ggtggtatta ttctcggcgg acgttccttt
     9961 gaaccgttgg ggctgaaaaa agactttaac tttggggaaa ttacggcggc ggatattggt
    10021 cgtatgaatg tgactaaaga agagcgtgat aaattgcgtc agaaagtacc cggtttacgt
    10081 aacgttgctt taacggcacc gtacttccat cgcggtgacg tgccgacgct ggacggggcg
    10141 gtgaaactga tgctgcgcta tcaggtaggc aaagagctgc cgcaggagga tgtggatgat
    10201 atcgtagctt tcctgcacag tctgaacggg gtgtacacgc cgtatatgca ggataaacaa
    10261 taattaattt gatcgcccga acaggaatgt ttgggcgatt tttattacga taataaagtc
    10321 tgtttttaat attatcatgt taaatgttta tattataaaa agtcgttttt ctgcttagga
    10381 ttttgttatt taaattaagc ctgtaatgcc ttgcttccat tgcggataaa tcctactttt
    10441 ttattgcctt caaataaatt taaggagttc gaaatggacc agaagctgtt aacggatttc
    10501 cgctcagaac tactcgattc acgttttggc gcaaaggcca tttctactat cgcggagtca
    10561 aaacgatttc cgctgcacga aatgcgcgat gatgtcgcat tccagattat caatgatgaa
    10621 ttatatcttg atggcaacgc tcgtcagaac ctggccactt tctgccagac ctgggacgac
    10681 gaaaacgtcc ataaattgat ggatttgtcg atcaataaaa actggatcga caaagaagaa
    10741 tatccgcaat ccgcagccat cgacctgcgt tgcgtaaata tggttgccga tctgtggcat
    10801 gcgcctgcgc cgaaaaatgg tcaggccgtt ggcaccaaca ccattggttc ttccgaggcc
    10861 tgtatgctcg gcgggatggc gatgaaatgg cgttggcgca agcgtatgga agctgcaggc
    10921 aaaccaacgg ataaaccaaa cctggtgtgc ggtccggtac aaatctgctg gcataaattc
    10981 gcccgctact gggatgtgga gctgcgtgag atccctatgc gccccggtca gttgtttatg
    11041 gacccgaaac gcatgattga agcctgtgac gaaaacacca tcggcgtggt gccgactttc
    11101 ggcgtgacct acaccggtaa ctatgagttc ccacaaccgc tgcacgatgc gctggataaa
    11161 ttccaggccg acaccggtat cgacatcgac atgcacatcg acgctgccag cggtggcttc
    11221 ctggcaccgt tcgtcgcccc ggatatcgtc tgggacttcc gcctgccgcg tgtgaaatcg
    11281 atcagtgctt caggccataa attcggtctg gctccgctgg gctgcggctg ggttatctgg
    11341 cgtgacgaag aagcgctgcc gcaggaactg gtgttcaacg ttgactacct gggtggtcaa
    11401 attggtactt ttgccatcaa cttctcccgc ccggcgggtc aggtaattgc acagtactat
    11461 gaattcctgc gcctcggtcg tgaaggctat accaaagtac agaacgcctc ttaccaggtt
    11521 gccgcttatc tggcggatga aatcgccaaa ctggggccgt atgagttcat ctgtacgggt
    11581 cgcccggacg aaggcatccc ggcggtttgc ttcaaactga aagatggtga agatccggga
    11641 tacaccctgt acgacctctc tgaacgtctg cgtctgcgcg gctggcaggt tccggccttc
    11701 actctcggcg gtgaagccac cgacatcgtg gtgatgcgca ttatgtgtcg tcgcggcttc
    11761 gaaatggact ttgctgaact gttgctggaa gactacaaag cctccctgaa atatctcagc
    11821 gatcacccga aactgcaggg tattgcccag cagaacagct ttaaacacac ctgataacat
    11881 aacgttgtaa aaaccgaatg cccagccttt aaaaaaacag ctgggcattc ggttgcttat
    11941 taatcgcaat aatatattgg ctgtctattc atcgtgttga taagatatat gttatatgaa
    12001 tgtttattaa atgtagcgat tgcctttaat gtcacgaaaa gggattattt tcttgctatt
    12061 aatttcactg cgttcttaaa cacgtttttg tattataaat ccagtcatcc tgcccgtaga
    12121 acatcacaca ttatcatcct gttctcccgc ttcgtttaaa tttatttatc aatcaatttg
    12181 acttaagagg gcggcgtgct acattaatta acagtaatat gtttatgtaa tattaagtca
    12241 actatgcaat cattacatgg gaattgtcta attgcgtacg caagacataa atatattctc
    12301 accatggtta atggtgaata tcgctatttt aatggcggtg acctggtttt tgcggatgca
    12361 agccaaattc gagtagataa gtgtgttgaa aattttgtat tagtatcaag ggatacgctt
    12421 tcattatttc tgccgatgct caaggaggag gcattaaatc ttcatgcaca taaaaaaatt
    12481 tcttcattac tcgttcatca ctgtagcaga gatattcctg tttttcagga agttgcgcaa
    12541 ctatcgcaga ataagaatct tcgctatgca gaaatgctac gtaaaagagc attaatcttt
    12601 gcgttgttat ctgtttttct tgaggatgag cactttatac cgctgctttt gaacgttttg
    12661 caaccgaaca tgcgaacacg agtttgtacg gttatcaata ataatatcgc ccatgagtgg
    12721 acactagccc gaatcgccag cgagctgttg atgagtccaa gcctgttaaa gaaaaaattg
    12781 cgcgaagaag agacatcata ttcacagttg cttactgagt gtagaatgca acgtgctttg
    12841 caacttattg ttatacatgg cttttcaatt aagcgagtcg cagtgtcctg tggatatcac
    12901 agcgtgtcgt atttcattta cgtctttcga aattattatg ggatgacgcc cacagagtat
    12961 caggagcgat cggcgcaggg attgccgaac cgtgactcgg cggcaagtat tgttgcgcaa
    13021 ggaaattttt acggcactga ccgttctgcg gaaggaataa gattatagaa ttttactcag
    13081 acataaaaaa aacccggcat aggggaccgg gaagaggata gtctgccgtc tccagactaa
    13141 taaaccgtta taacactccc tgttggcacg ggaaactttg tgctctcagt aagttaaata
    13201 taacttttac tggaaataag atcagccatt tttttataaa cataagctat acgcagtgcg
    13261 aaaatatatt cgtgctgcat ttacttatta tcaattaact gttatgcaaa actactttgt
    13321 ggataaattt tggtcctacc aaatctggca gttttttcgc taagaaacag tctggcaaca
    13381 tttcattagt atactgaaat tgaaataatc gcagtatgaa atataaggga taatcatgac
    13441 tcatgtctgc tcggtgatcc tcattcgtcg ttcattcgat atttatcatg aacagcataa
    13501 aatatcgctg cataacgaga gtatcgtgct gctggagaaa aatttggcag acgattttgc
    13561 gttttgttca ccggatacgc gacgactgga tatcgatgag ctgacagttt gccattactt
    13621 acaaaatatt cgtcagctac cacgcaattt agggttacat agcaaagacc gtctattaat
    13681 taaccagtca ccccccatgc cgctggtgac ggcgattttt gatagcttca atgaatccgg
    13741 ggtaaattca ccgatactga gcaatatgct ctacctttcc tgtttatcga tgttttctca
    13801 taagaaagaa ctgatcccct tacttttcaa tagcatcagc actgtttcag gaaaagttga
    13861 acgccttatt agctttgata tcgccaaacg ttggtatctg cgcgatatcg cggaaagaat
    13921 gtataccagc gagagtctca tcaaaaaaaa gttgcaggat gaaaatacct gtttcagtaa
    13981 aatattactc gcttccagga tgtcgatggc cagacgatta ctcgagttac gtcaaattcc
    14041 tctgcatact attgcagaaa aatgtggcta tagcagtacg tcgtacttta taaacacatt
    14101 tcgacaatat tatggtgtaa cgccacatca gtttgcgcaa cattcgccag gtaccttttc
    14161 ctgacatatt ttgcatttga atattggtca ggatctcaca cctgcttcat gtgaaactct
    14221 tccctgatga tttctgccgg gctaccggct agttctcttt cgcagtttgc caggcggtat
    14281 aggtattttc aggaggaaaa gactcggcat gtttgggatt attaagctga caattcatac
    14341 gattacggga atgtgggtca gtattgtgct gttcaaattg atgacgaatg gctggagtgg
    14401 tttctacttt cagtgctgtg tactaagcct ggtattcctg acggttagct ggttgttgag
    14461 tggtgaatgg ttagcaggaa agagtaaggc tgaaccttca cgttcaacct tactctcatt
    14521 tacacgttac gcttttttaa agcgggcaaa gagatgttcc actacaacga aaaagaccgg
    14581 aacgaagtaa attgccagca ctgttgcggc aaacatcccg cccatcacgc cggtacctac
    14641 cgcgttttgc gcgccagaac cggcaccatg actgataacc agcggcagca cgccgagaat
    14701 aaaggccaga gaggtcatca ggattgggcg taaacgcatc cgcgccgctt cgatgattgc
    14761 ctctatcggc gttttccctt ctttctgcat catctcaacg gcaaattcga caatcaggat
    14821 ggcgttcttg gcggaaagcc cgatggtggt cagcaaacca acctggaagt agacgtcatt
    14881 acttaagccg cgcagatcgg tggccagtaa tgcgccaacg acgcctaacg gaacaaccaa
    14941 catcaccgag aacggaattg accagctctc atagagtgcg gcgagggcga ggaacaccac
    15001 gaccagtgaa atggcataca gtgcaggagc ctggtttgag gataacgctt cctgatacga
    15061 cagtccggtc catgagtagc cgacgcctgc cggaagttta gcgaccaggt ctgccataaa
    15121 tttcatagcg tcaccggtac ttttcccggc cgccgcttca cctaaaatct ccattgacgg
    15181 gatgccgttg tagcgttcca atcgcggtga accataggtc cattcggtag acgagtaggc
    15241 agaaagcggt gccatcgtgc cagaggcgtt gcgtacatac cattggttga tgttatccgg
    15301 caacatacgg aacggcgtgc ctgcctggac atacactttt ttcacccgcc cctggttgag
    15361 gaagtcgttc acgtagctgc tgccgaaggc ggtggaaatt gtctggttga tatcagacag
    15421 cgccacaccc attgcctcag ctttcgcggc gttgacgttc actttgaaca tcggcgtatc
    15481 ttccaggccg ttcgggcgta ccccggtgac ctggtcaggc gattgcgctg ccagtgataa
    15541 cagctcgttt cgtgcctggg ttagtttttc gtgccccagg ttaccgttgt ccagcagttc
    15601 catatcaaaa cctgacgcgg tacccagttc agccaccgcg ggtaagttga acgggaagac
    15661 gacggcttta ttgatactgc ttaacgcaat cattgcccgc tgaatgatcg cggtaaccga
    15721 gttttcctca ccgacacgtt cagaccacgg cttgagactg ataaacgcca ggccgttgtt
    15781 ttgcccctgg ccgctgaagc caaagccgcc aacggtaaac accgactgaa cattatcttt
    15841 ctcttttgta agataataat ccgtcacctg ttgcagcact ttcgtggtgt taaccatggt
    15901 ggcaccggaa ggtaactgcg cggtggtcat aaataccccc tgatcctctt ctggtaagaa
    15961 agaggtcggt gtacgcagga acagcaccgc catcccggcg caaatcagca ggtagaccac
    16021 catgtagcga ccggtacaac gcaacagcga gcgggtgcta tcggtatagt gctgagttga
    16081 tttttcaaac agcgtgttga agcgtgcgaa cagggcgtta ggtttgtgac cgccttccgg
    16141 cgcggctttc agaatggtgg cgcacagggc aggggtcagg ctcattgcca caaatactga
    16201 aagcagcatg gaggagatca gcgtgatgga gaactggcgg tagatctccc cggttgcgcc
    16261 gctcataaag gccatcggca taaacactgc ggaaagaaca acagcaatac cgaccagcgc
    16321 acgttggatc tgccccatcg atttatgcgt cgcttccttc ggtggtagct tatcttccgc
    16381 aatgacacgc tcgacgttct ccaccaccac gatggcgtca tccaccagta accctatcgc
    16441 cagcaccatc ccgaacatag ttaacgtgtt gatggtgaaa ccgaccgccg acaagatcgc
    16501 aaacgtcccg agaataacca ccggtacggc aatcgtcggg atgattgtgg cacggaaatt
    16561 ctgcaaaaac agatacatga ccaggaagac gaggatgata gcctcaacca gtgttttaaa
    16621 aacttcctga atagaaattt cgataaacgg cgtggtgtcg taaggataaa ccgtcttcag
    16681 acttgcgggg aaataggctg ataagcggtt cagctcctct ttgactgccc gcgaggtatc
    16741 cagggcgttt gctccggtag ccagtttgat ggcgatcccg gcagcaggtt tgccgttata
    16801 gcgcgccacg gtggaataat cttccgctcc aagttcgacg cgggcgacat cacgcagcag
    16861 cacttgcgaa ccatcttgct gaactttcaa caggattttg ccaaattctt ccggcgtttg
    16921 cagacgcgtc tgcacaatga tcgaggcgtt tagttgctgg tctgccgcct gtggcatgcc
    16981 acccagttga ccaccggaaa tctggttgtt ttgcacctta atctgggaaa taacatcgga
    17041 aggtaccaga ttgtatttat tgagtttttg cgggtccagc cagatacgca tggcgtactc
    17101 ggaaccaaag agctgtacgc taccaacgcc cgcggtacgg cttagcgggt ctttgatatt
    17161 agacgctaca tagtccgcga tatcgtactg gttgaggctg ccgttatcag aaataaacgc
    17221 cgctaccatc agaatattac tgctcgactt atcaacgcta atcccctgct gctgcaccgc
    17281 ttcaggtaat gaaggcatag cgagttgcag tttattttgc acctgaacct gtgcgatatc
    17341 aggagatgtc ccagtctcga aggtcagagt gatagaggca ttacccgccg catcactggt
    17401 tgaagacatg tacatcaggc catcaagccc attcatattt tgctcaatca cctgagtgac
    17461 cgagtcttct accgtttgcg catcggcacc tggataggta gcgctgacgg taatggtcgg
    17521 tggcgcaatc tgcggatact gcgcaaccgg taagttcatg atcgccagac cacctgcaag
    17581 catcataata atggcaagta cccaggcaaa aaccgggcga tcaataaaat agttagccat
    17641 gaaagtcccc ttaagcctgc aacgttattg tttcgattcg gtgctggcgt tttcctggct
    17701 ggaggaaatt gctcgtgctt tgatacccgg acgaatgcgt tgcaaaccgg aaacgatcac
    17761 ccgatcgcca gcctgcaagc cagaggtgac aacccactgg tcgccgatgg ctttgctggc
    17821 ttcaatttcg cgtagctgca caacatcgtc tttatccaga atgagcgccg ttgctttacc
    17881 ctgggcgttg tgggtgacgc cttcctgcgg caccagtaat acattctggc ggctaccttc
    17941 atccactaat gccgtgacgt acatgccagg cagcaagtca ccatttgggt tggggaaaat
    18001 cgcccgtaac gtcacggagc ccgtggtttc atccaccgtc gggtcggaga atttcagcgt
    18061 gccggtctgg ctgtagcgtt taccattttc cagattgagc tgtactggcg tactgccctg
    18121 aacctgtttg atttgcccac tggcgacctc ttctttcatg cgtaagaaat cctgcaccga
    18181 ctgcgtgaga tcgacataaa tcgggtccag acgttgtacg gtaaccagcg aatctgcctg
    18241 attagcggta acgagtgcgc cgacggtcac cgacgatttc ccgctgacgc ccgtaatcgg
    18301 cgaggtgaca ttcgcgtatt gcagattgat cgtcgcctgt tcaacagccg ctttggcgac
    18361 ggtgacattg gcttctgctt cattcaactg ggtgcgcgcg gtgtcgtaat cctgacggct
    18421 aacgtagttg gtcttcagca acgatgcctg gcggttaaag gtgatgcggg cattgctggc
    18481 ggtagagagc gctttcgcca gcgagccttt ggcggagttt agctcggcct gtaaaggtgc
    18541 aggatcaatc tgatacagcg aatcgccctg gttcacttta tcgccttcga taaagttgcg
    18601 tttaatgata ataccgccca cctggggacg tatctcggca acttcataag gaacggttct
    18661 accgggcaat tcgctcaaca cattgaccga accgggggag agtgtgacga caccgacctc
    18721 aggcgtcatg gcggcggcgt tttccgccga tttgtcatcg caggcggtga gcatcgcgcc
    18781 gcagaataac aacggtatta acagctttct tcttctgttc attttagtcc ctgaaaattc
    18841 ttgagaaata acggttcttt aaattgcgcg cgaggagaga tatgagggat ttacagacca
    18901 gcggcatagt ggggttgtca gccagtaagg tgggatacag gtatagtgat cgacatggtg
    18961 aggtcaacga caaaaaaaat gttgccgttc tgccaacagt tcctgccagc attcgggcaa
    19021 cgaagggttc tactggtgga tacacatacc aggggaataa agtcgtttta gcctctcctt
    19081 tagtaatcac cgggggtaat gaaatcagca tctgcatccc tcgtcatgcc agccatcaat
    19141 ttcagttgct tatgtcctga ctaaaaataa gatgtgatac ccagggtgac gatgtcgctc
    19201 atacgtctta gtttcagctt gtacataatg ttgaatttct gaatctttaa tgtttgttgc
    19261 gaaatattga gcgtcgacgt gatattgctt tcatttttat ttttcagaat cagttgcata
    19321 attttgaact gattatgtga aaaacataat tgtgaattct tatggggcaa gtgtttacca
    19381 taagtaatct caagaagatt tttgatactt tctttgcggc taacaaaata aataggcgct
    19441 ttagctttta gtttactgat gtgataaggt gccaaaacaa taattctctc ggcatctaat
    19501 ttctccagaa atttaatcgc ttcttcatca aggatatgat tgtgataggt atcaatgata
    19561 accttgaagg gtttattgcc tacttttttg atctctgaca gggaattgat ttttatcatt
    19621 tcgtgattat ctttcaactg ccaaaagccc tgtaaaagaa aagaatcttt cgtcatgaga
    19681 aaaatcataa cttgctcctt agccgttatc gtttcgaaca tgtcatcctt ttcattattt
    19741 acatccttgt ccgaatcgtt gttcaatata gtaaacgcct ataagaactt tgcccttcgt
    19801 gaactaatac gtctattaac actaatcaat acttcagatt tatccatcac gcactccata
    19861 tattgatcct aagtaagatt cctggttgtt atcagtttgt aaacagtaaa caaaaagtta
    19921 acgtttgcgg attactgccc aagaataagt tatcaataac cagtttgtga tctctgaaga
    19981 atattactaa agttaaaatg taatccgatt taaatatcga gtctccttgt ttcgacttaa
    20041 gctggcaatt ggattgccag ctttctttta acgcattgaa attacctgag taaataacgc
    20101 attcatgtct tcaggttttt atatagcgtc tggagacacg gatatttatg caatgtaatc
    20161 aatgccagtt gcaaaaaaat gaacccggat tacttattta accgcccata gcatcaacgc
    20221 ttacggaact ctttgttcac tttcccactg cacttttaaa acattaaacc tgactacgga
    20281 aaatatcagc catgataatg tttgaaatgg ctaatttgcc atggagtgaa aaaaattata
    20341 tgaaattcag taggttgaaa taatcactag caggtaatta tttcaatgat agtgcgcaat
    20401 tgatctacaa cgctgcgtag cggagatagt attaatcgga tcatagtcac atcaagtgac
    20461 tatgatccgg gtgacaaccg ggataattat tgctgcttaa cgaacaaact ggcgaagctg
    20521 aacaggctgg cggcgctaaa tatcagttca attcccacca gtgtggaaac cagcgttaca
    20581 gacaccatcg gcgttgcacc aaggaatatc caggcaatga cgatatccag cacaccaata
    20641 acgagctgta gccagctgcc tttcattgaa cgctgacgat accaactcat caggcgaata
    20701 acccctgcaa cacagaacaa accggcaata aatgccgcaa tggcaaaaat gcccagctcc
    20761 ggtgcgcgga tgaagaaata gccgatcaat aaataggcga ctgcgacgag gaaaccggat
    20821 aataccggcc agaaattatg actgcggttg ctgaataacc cgacaataag cgcaatgccc
    20881 gagcagatta ataatgcacc cactactgtg cttaaaatat cgccagagac gaacgggaaa
    20941 ctgatacaca gcaacccgac gataaacaac agcacggcaa taaactggat tgctctgcga
    21001 tgttttttaa gcatctccag atcaaacttc aaaattgttg ccttatctat atataacata
    21061 gaaccaccct ataaaattaa gaagaaaatc ccctgctatc aatctatgcc aaaaacgcgt
    21121 ctaagaatgc agtcgattta ataaaaattt cctaatt
//
LOCUS       DAPGUL010000078        21055 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.079, whole genome shotgun sequence.
ACCESSION   DAPGUL010000078 DAPGUL010000000
VERSION     DAPGUL010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21055
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.079"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            515..1255
                     /locus_tag="RHX21_003081"
     CDS             515..1255
                     /locus_tag="RHX21_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin family protein"
                     /protein_id="HDV1988234.1"
                     /translation="MKKIIAVSALAVAGMFSAQTLANESKTGFYMTGKAGTSVLSLSN
                     QRFVEGEGEWADRYKGGDDHDTVFSGGIAAGYDFYPQFSIPVRTELEFYARGKADSKY
                     NVDKDSWSGGYWRDDLKNEVSVNTLMLNAYYDFRNDSAFTPWVSAGIGYARIHQKTTG
                     ISTWDYGYGSSGRESLSRSGSADNFAWSFGAGVRYDVTPDIALDLSYRYLDAGDSSVS
                     YKDEWGDKYKSEVDVKSHDIMLGVTYNF"
     gene            1407..2909
                     /locus_tag="RHX21_003082"
     CDS             1407..2909
                     /locus_tag="RHX21_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001608786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HDV1988235.1"
                     /translation="MNIRKLFCPGNTPQILLFLFFFIVSVITTIACGYTEKNATGNVL
                     LLFLLLLLAHRNTLTSITALLFLFCCALYAPAGMTYGKINNSFIVALLQTTTDEAAEF
                     TGMIPVYHFLVSAAILVFMVIFWRTHHRGHRNGMALLLFVLCSVNSWPLRMVKGTVVG
                     TTDTLREMQHYKQLSQHGADNWKILPGTPLYDTIVIVTGESVRRDYMSVYGYPVPTTP
                     WLNMAPGLFIDGYTSAAASTVPSLSRTLIYDYEQNPDSGNNVVALAAKAGYSTWWISN
                     QGKLGEHDTRISVIASDAEHTVFLKKGSFASRKTDDMLLLQETERALADKSSPKVIFL
                     HMMGSHPNPCDRLHSWPNHYLEQYPRKVACYLASISKLDNFLGQLDGILRRYSRHFAM
                     LYFSDHGMSVSDSANPVHHDGHVQGGYSVPLIITASDITSHQSVSRKISARHFAGIFQ
                     WLTGIRTENIPPFNPLINEDNETVMVFNGEKIVPADGLKSQPVILPGKGK"
     gene            complement(3174..4436)
                     /locus_tag="RHX21_003083"
     CDS             complement(3174..4436)
                     /locus_tag="RHX21_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
                     /protein_id="HDV1988236.1"
                     /translation="MALTDAKIRAAKPTDKAYKLTDGAGMFLLVHPNGSRYWRLRYRI
                     LGKEKTLALGVYPEVSLSEARTKRDEARKLISEGIDPCEQKRVKKVVPDLQLSFEHIA
                     RRWHASNKQWAQSHSDKVLKSLETHVFPFIGNRDITTLNTPDLLIPVRAAEAKQIYEI
                     ASRLQQRISAVMRYAVQSGIIRYNPALDMAGALTTVKRQHRPALELSRLPELLSRIDS
                     YKGQPVTRLAVMLNLLVFIRSSELRYARWSEIDIDNSMWTIPAEREPLPGVKFSHRGS
                     KMRTPHLVPLSKQVVAILAELQTWAGENGLIFTGAHDPRKPISENTVNKALRVMGYDT
                     TQDVCGHGFRAMACSALIESGLWSRDAVERQMSHQERNGVRAAYIHKAEHLEERRLML
                     QWWADFLDANREQCISPFEYAKINNPLK"
     gene            complement(4634..4709)
                     /locus_tag="RHX21_003084"
     tRNA            complement(4634..4709)
                     /locus_tag="RHX21_003084"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4674..4676),aa:Phe,seq:gaa)
     gene            complement(4815..5522)
                     /locus_tag="RHX21_003085"
     CDS             complement(4815..5522)
                     /locus_tag="RHX21_003085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HDV1988237.1"
                     /translation="MVIGPFINASAVLLGGVLGALLSQRLPERIRVSMTSIFGLASLG
                     IGILLVVKCANLPAMVLATLLGALIGEICLLEKGVNTAVAKAQNLFRHSRKKPAHESF
                     IQNYVAIIVLFCASGTGIFGAMNEGMTGDPSILIAKSFLDFFTAMIFACSLGIAVSVI
                     SIPLLIIQLTLAWAAALILPLTTPSMMADFSAVGGLLLLATGLRICGIKMFPVVNMLP
                     ALLLAMPLSAAWTAWFA"
     gene            5920..8055
                     /gene="speC"
                     /locus_tag="RHX21_003086"
     CDS             5920..8055
                     /gene="speC"
                     /locus_tag="RHX21_003086"
                     /EC_number="4.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311868.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine decarboxylase"
                     /protein_id="HDV1988238.1"
                     /translation="MKSMNIAASSELVSRLSTHRRVVALGDTDFTDVAAVVITAADSR
                     SGILTLLKRTGFHLPVFLYSEHAVELPAGVTAVINGNEQHWLELESAACQYEENLLPP
                     FYDTLTQYVEMGNSTFACPGHQHGAFFKKHPAGRHFYDFFGENVFRADMCNADVKLGD
                     LLIHEGSAKDAQKFAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKS
                     NHHGALIQAGATPVYLEASRNPFGFIGGIDAHCFNEEYLRQQIRDVAPEKADLPRPFR
                     LAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAWVGYEQFIPMMADSSPLLLELNE
                     NDPGIFVTQSVHKQQAGFSQTSQIHKKDNHIRGQARFCPHKRLNNAFMLHASTSPFYP
                     LFAALDVNAKIHEGESGRRLWAECVELGIESRKAILARCKLFRPFIPPVVDGKLWQDY
                     PTSVLASDRRFFSFEPGAKWHGFEGYAADQYFVDPCKLLLTTPGIDAETGEYSDFGVP
                     ATILAHYLRENGIVPEKCDLNSILFLLTPAESHEKLAQLVAMLAQFEQHIEDDSPLAE
                     VLPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLQKAMFRQQSFPSVVMNPQDAH
                     SAYIRGDVELVRIRDAEGRIAAEGALPYPPGVLCVVPGEVWGGAVQRYFLALEEGVNL
                     LPGFSPELQGVYSETDADGMKRLYGYVLK"
     gene            complement(8105..9361)
                     /gene="nupG"
                     /locus_tag="RHX21_003087"
     CDS             complement(8105..9361)
                     /gene="nupG"
                     /locus_tag="RHX21_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311867.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease NupG"
                     /protein_id="HDV1988239.1"
                     /translation="MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVY
                     SSLGIAAVFMPALLGIVADKWLSAKWVYAICHTIGAITLFMAAQVTTPEAMFLVILIN
                     SFAYMPTLGLINTISYYRLQNAGMDIVTDFPPIRIWGTIGFIMAMWVVSLSGFELSHM
                     QLYIGAALSAILVLFTLTLPHIPVAKQQANQSWTTLLGLDAFALFKNKRMAIFFIFSM
                     LLGAELQITNMFGNTFLHSFDKDPMFASSFIVQHASIIMSISQISETLFILTIPFFLS
                     RYGIKNVMMISIVAWILRFALFAYGDPTPFGTVLLVLSMIVYGCAFDFFNISGSVFVE
                     KEVSPAIRASAQGMFLMMTNGFGCILGGIVSGKVVEMYTQNGITDWQTVWLIFAGYSV
                     VLAFAFMAMFKYKHVRVPTGTQTVSH"
     gene            complement(9563..10642)
                     /gene="mltC"
                     /locus_tag="RHX21_003088"
     CDS             complement(9563..10642)
                     /gene="mltC"
                     /locus_tag="RHX21_003088"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417438.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     MltC"
                     /protein_id="HDV1988240.1"
                     /translation="MKKYLALALIAPLLISCSTTKKGDTYNEAWVKDTNGFDILMGQF
                     AHNIENIWGFKEVVIAGPKDYVKYTDQYQTRSHINFDDGTITIETIAGTEPAAHLRRA
                     IIKTLLMGDDPSSVDLYSDVDDITISKEPFLYGQVVDNTGQPIRWEGRASNFADYLLK
                     NRLQSRSNGLRIIYSVTINMVPNHLDKRAHKYLGMVRQASRKYGVDESLILAIMQTES
                     SFNPYAVSRSDALGLMQVVQHTAGKDVFRSQGKSGTPSRSFLFDPASNIDTGTAYLAM
                     LNNVYLGGIDNPTSRRYAVITAYNGGAGSVLRVFSNDKIQAANIINTMTPGDVYQTLT
                     TRHPSAESRRYLYKVNTAQKSYRRR"
     gene            complement(10707..10982)
                     /locus_tag="RHX21_003089"
     CDS             complement(10707..10982)
                     /locus_tag="RHX21_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative damage protection protein"
                     /protein_id="HDV1988241.1"
                     /translation="MSRTIFCTFLQREAEGQDFQLYPGELGKRIYNEISKEAWAQWQH
                     KQTMLINEKKLNMMNAEHRKLLEQEMVNFLFEGKEVHIEGYTPEDKK"
     gene            complement(11010..12062)
                     /gene="mutY"
                     /locus_tag="RHX21_003090"
     CDS             complement(11010..12062)
                     /gene="mutY"
                     /locus_tag="RHX21_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HDV1988242.1"
                     /translation="MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQ
                     VATVIPYFERFMARFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVATLHGG
                     KFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEV
                     ENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWAL
                     YPGKKPKQTLPERTGYFLLLQHEDEVLLAQRPPSGLWGGLYCFPQFADEESLRHWLAQ
                     RQIAADNLTQLTAFRHTFSHFHLDIVPMWLPVSSFTGCMDEGNALWYNLAQPPSVGLA
                     APVERLLQQLRTGAPV"
     gene            12223..12942
                     /gene="trmB"
                     /locus_tag="RHX21_003091"
     CDS             12223..12942
                     /gene="trmB"
                     /locus_tag="RHX21_003091"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HDV1988243.1"
                     /translation="MKNDVISPEFDENGRPLRRIRSFVRRQGRLTKGQEHALENYWPV
                     MGVEFSEDMLDFPALFGREAPVTLEIGFGMGASLVAMAKDRPEQDFLGIEVHSPGVGA
                     CLASAHEEGLSNLRVMCHDAVEVLHKMIPDNSLRMVQLFFPDPWHKARHNKRRIVQVP
                     FAELVKSKLQLGGVFHMATDWEPYAEHMLEVMSSIDGYKNLSESNDYVPRPASRPVTK
                     FEQRGHRLGHGVWDLMFERVK"
     gene            12942..13268
                     /locus_tag="RHX21_003092"
     CDS             12942..13268
                     /locus_tag="RHX21_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417434.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggL family protein"
                     /protein_id="HDV1988244.1"
                     /translation="MAKNRSRRLRKKMHIDEFQELGFSVAWRFPEGTSEEQIDKTVDD
                     FINEVIEPNKLAFDGSGYLAWEGLICMQEIGKCTEEHQAIVRKWLEERKLDEVRTSEL
                     FDVWWD"
     gene            13452..14171
                     /locus_tag="RHX21_003093"
     CDS             13452..14171
                     /locus_tag="RHX21_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2884 domain-containing protein"
                     /protein_id="HDV1988245.1"
                     /translation="MMRKMLLAAALSVTAMTAHADYQCSVTPRDDVIVSPQTVQVKGE
                     NGNLVITPDGNVMYNGKQYSLNAAQREQAKDYQAELRSTLPWIDEGAKSRVEKARIAL
                     DKIIVQEMGESSKMRSRLTKLDAQLKEQMNRIIETRSDGLTFHYKAIDQVRAEGQKLV
                     NQAMGGILQDSINEMGAKAVLKSGGNPLQNVLGSLGGLQSSIQTEWKKQEKDFQQFGK
                     DVCSRVVTLEDSRKALVGNLK"
     gene            14347..15393
                     /gene="ansB"
                     /locus_tag="RHX21_003094"
     CDS             14347..15393
                     /gene="ansB"
                     /locus_tag="RHX21_003094"
                     /EC_number="3.5.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-asparaginase 2"
                     /protein_id="HDV1988246.1"
                     /translation="MEFFKKTALAALVMGFSGAALALPNITILATGGTIAGGGDSATK
                     SNYTAGKVGVENLVNAVPQLKDIANVKGEQVVNIGSQDMNDNVWLTLAKKINTDCDKT
                     DGFVITHGTDTMEETAYFLDLTVKCDKPVVMVGAMRPSTSMSADGPFNLYNAVVTAAD
                     KASANRGVLVVMNDTVLDGRDVTKTNTTDVATFKSVNYGPLGYIHNGKIDYQRTPARK
                     HTSDTPFDVSKLNELPKVGIVYNYANASDLPAKALVDAGYDGIVSAGVGNGNLYKSVF
                     DTLATAAKNGTAVVRSSRVPTGATTQDAEVDDAKYGFVASGTLNPQKARVLLQLALTQ
                     TKDPQQIQQIFNQY"
     gene            15510..16517
                     /locus_tag="RHX21_003095"
     CDS             15510..16517
                     /locus_tag="RHX21_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1202 family protein"
                     /protein_id="HDV1988247.1"
                     /translation="MKKQWIVGTALLMLMTGNAWADGEPPTENILKDQFKKQYHGILK
                     LDAITLKNLDAKGNQATWSAEGDVSSSDDLYTWVGQLADYELLEQTWTKDKPVKFSAM
                     LTSKGTPASGWSVNFYSFQAAASDRGRVVDDIKTNNKYLIVNSEDFNYRFSQLESALN
                     TQKNSIPALEKEVKALDKQMVAAQKAADAYWGKDANGKQMTREEAFKKIHQQRDEFNK
                     QNDSEAFAVKYDKEVYQPAIAACHKQSEECYEVPIQQKRDFDINEQRRQTFLQSQKLS
                     RKLQDDWVTLEKGQYPLTMKVSEINSKKVAILMKIDDINQANERWKKDTEQLRRNGVI
                     K"
     gene            complement(16672..17808)
                     /gene="hemW"
                     /locus_tag="RHX21_003096"
     CDS             complement(16672..17808)
                     /gene="hemW"
                     /locus_tag="RHX21_003096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HDV1988248.1"
                     /translation="MVKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLL
                     NDLDNDVAYAQGREVKTIFIGGGTPSLLSGPAMQTLLDGVRARLPLAADAEITMEANP
                     GTVEADRFVDYQRAGVNRISIGVQSFSEEKLKRLGRIHGPQEAKRAAKLASGLGLRSF
                     NLDLMHGLPDQSLEEALGDLRQAIELNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALW
                     DIFEQGHQLLTAAGYQQYETSAYAKPGYQCQHNLNYWRFGDYIGIGCGAHGKVTFPDG
                     RILRTTKTRHPRGFMQGRYLESQRDVEAADKPFEFFMNRFRLLEAAPRVEFIAYTGLC
                     EDVIRPQLDEAIAQGYLTECADYWQITEHGKLFLNSLLELFLAE"
     gene            complement(17801..18394)
                     /locus_tag="RHX21_003097"
     CDS             complement(17801..18394)
                     /locus_tag="RHX21_003097"
                     /EC_number="3.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XTP/dITP diphosphatase"
                     /protein_id="HDV1988249.1"
                     /translation="MQKVVLATGNAGKVRELASLLSDFGLDIVAQTDLGVDSAEETGL
                     TFIENAILKARHAAKVTGLPAIADDSGLAVDVLGGAPGIYSARYSGEDATDLKNLQKL
                     LETLKDVPDDQRQARFHCVLVYLRHAEDPTPLVCHGSWPGVITREPAGTGGFGYDPIF
                     FVPSEGKTAAELTREEKSAISHRGQALKLLLDALRNG"
     gene            complement(18402..18692)
                     /locus_tag="RHX21_003098"
     CDS             complement(18402..18692)
                     /locus_tag="RHX21_003098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417428.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggU family protein"
                     /protein_id="HDV1988250.1"
                     /translation="MSAVTVNDDGLVLRLYIQPKASRDSIVGLHGDEVKVAITAPPVD
                     GQANSHLVKFLGKQFRVAKSQVVIEKGELGRHKQIKIINPQQIPPEIAALIN"
     gene            complement(18689..19255)
                     /gene="yggT"
                     /locus_tag="RHX21_003099"
     CDS             complement(18689..19255)
                     /gene="yggT"
                     /locus_tag="RHX21_003099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotic shock tolerance protein YggT"
                     /protein_id="HDV1988251.1"
                     /translation="MNTLTFLLSTVIELYTMVLLLRIWMQWAHCDFYNPFSQFVVKVT
                     QPIIGPLRRVIPAMGPIDSASLLVAYILSFIKAIVLFKVVTFLPIIWIAGLLILLKTI
                     GLLIFWVLLVMAIMSWVSQGRSPIEYVLIQLADPLLRPIRRLLPAMGGIDFSPMILVL
                     LLYVINMGVAEVLQATGNMLLPGLWMAL"
     gene            complement(19273..19977)
                     /gene="yggS"
                     /locus_tag="RHX21_003100"
     CDS             complement(19273..19977)
                     /gene="yggS"
                     /locus_tag="RHX21_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate homeostasis protein"
                     /protein_id="HDV1988252.1"
                     /translation="MNDIAHNLAQVRDKISAAATRCGRSPEEITLLAVSKTKPASAIA
                     EAIDAGQRQFGENYVQEGVDKIRHFQELGVTGLEWHFIGPLQSNKSRLVAEHFDWCHT
                     IDRLRIATRLNDQRPAELPPLNVLIQINISDENSKSGIQLAELDELAAAVAELPRLRL
                     RGLMAIPAPESEYVRQFEVARQMAVAFAGLKTRYPHIDTLSLGMSDDMEAAIAAGSTM
                     VRIGTAIFGARDYSKK"
     gene            19995..20975
                     /locus_tag="RHX21_003101"
     CDS             19995..20975
                     /locus_tag="RHX21_003101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417425.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HDV1988253.1"
                     /translation="MNMEEIVALSVKHNVSDLHLCSAWPARWRIRGRMEAAPFDAPDV
                     EELLREWLDDDQRAILLENGQLDFAVSLAENQRLRGSAFAQRQGISLALRLLPSHCPQ
                     LEQLGAPPVLPELLKSENGLILVTGATGSGKSTTLAAMVGYLNQHADAHILTLEDPVE
                     YLYASQRCLIQQREIGLHCMTFASGLRAALREDPDVILLGELRDSETIRLALTAAETG
                     HLVLATLHTRGAAQAVERLVDSFPAQEKDPVRNQLAGSLRAVLSQKLEVDKQEGRVAL
                     FELLINTPAVGNLIREGKTHQLPHVIQTGQQVGMITFQQSYQQRVGEGRL"
BASE COUNT         5295 a         5117 c         5428 g         5215 t
ORIGIN      
        1 tcaaccaaac gttcaccgga cattagaaaa catggaaatt tcttgttttt aaatgctttt
       61 tacaccaata gcaaaattta cattccaaaa tcattagtct ttgcgtaatc aaaagatgta
      121 atggtttttt ccttactact tctagataat ccgcccacta cagcaacatc aacttacgct
      181 catctaaatg ctccgcctta tggatataag ccacccgcac tgaattacat tccatgcggc
      241 tcatcagacg tccagttgct ttactgtctt cagggggatg ctcttgtaat cccaacctct
      301 cgtgctttct gagcataaca catccatgtt gctgcgatta tctcttaaac ccgtccttac
      361 catttttatt gatacgataa ggaactttca tcatacatga tcgattttgt cgatcgattc
      421 gatcgaattt tctcttttta ccctgtcttt tacatggttt taaaataagc accccattta
      481 ttgttcgggg aaagtgatag cagaggtaac tgaaatgaaa aagattattg cggtttcggc
      541 acttgctgtg gcaggcatgt tttcagccca gaccctggct aatgagagca aaacaggctt
      601 ttatatgacc ggtaaggcgg gaacttccgt tttatctctt tccaaccagc gttttgtcga
      661 aggtgaagga gagtgggcgg acagatacaa aggtggcgat gaccatgata cggtattcag
      721 tggcggtatt gcggccggtt atgattttta tccgcaattc agtattccgg ttcgtacgga
      781 actggagttt tacgctcgtg gaaaagctga ttcgaagtat aacgtagata aagacagctg
      841 gtcaggcggt tactggcgtg atgacctgaa gaatgaggtg tcagtcaaca cactgatgct
      901 gaatgcgtac tatgacttcc ggaatgacag tgcattcaca ccatgggtat ctgcagggat
      961 tggctacgcc agaattcacc agaaaacaac cggtatcagt acctgggatt atgggtacgg
     1021 aagcagtggt cgcgaatcgt tgtcacgttc aggctctgct gacaacttcg catggagctt
     1081 tggcgcgggt gtccgctatg acgtaacccc ggatatcgct ctggacctca gctatcgcta
     1141 tcttgatgca ggtgacagca gtgtgagtta caaggacgag tggggcgata aatataaatc
     1201 agaagttgat gttaaaagtc atgacatcat gcttggtgtg acttataact tctgacaaaa
     1261 ctgctcctga aagataataa ttacccatct tctgtaatta aacgaagact ccctgcagta
     1321 attatactgc agggttgtct gttatctgtt tcacaggaga cttctgattt ttattctctt
     1381 cacaataatg ttgtcgatat actccgatga atatcagaaa actgttttgt ccgggcaata
     1441 caccccagat tttattgttt ttattctttt ttattgtttc tgtaataacc acaattgcat
     1501 gcggatacac tgagaagaat gccacaggaa atgtgctgct tctgtttctc cttcttctcc
     1561 ttgcacacag aaataccctc acatccatta cagcgctgtt atttctgttc tgttgtgcac
     1621 tgtatgcgcc tgccggtatg acgtacggta aaatcaacaa cagttttatt gtcgcgttgt
     1681 tgcagaccac aactgatgag gcagcggagt ttaccgggat gattcctgtt tatcattttc
     1741 tggtcagtgc cgcgattctg gtattcatgg tgattttctg gcggacacat caccgtggtc
     1801 accgtaacgg gatggcactg ctgctattcg tattatgctc agtaaacagt tggccgttgc
     1861 ggatggttaa aggaactgtt gtggggacaa ctgacacatt acgtgaaatg cagcattata
     1921 aacaactgag tcagcacggg gctgacaact ggaaaatcct gccgggaaca ccgttatatg
     1981 acacaattgt gattgtcact ggtgagagtg tgcgcaggga ttatatgtcg gtatatggtt
     2041 atcccgtgcc aaccacaccg tggctgaata tggctcccgg tttatttatt gacggctata
     2101 catcggcagc agccagtacc gtaccttccc tgagccggac actgatttat gactatgagc
     2161 agaaccctga ctccggcaac aacgtggtgg cgctggcagc aaaagcagga tacagcacat
     2221 ggtggatatc caatcaggga aaactggggg agcatgatac acgcatctct gttattgcat
     2281 ctgatgcgga gcataccgtt ttcctcaaga aaggcagctt tgcttcccgt aaaacggatg
     2341 acatgttgtt gttacaggaa acagaacgtg cactggcgga taaatcctct ccgaaggtga
     2401 ttttcctgca catgatgggg tctcatccga acccgtgtga ccggcttcac tcctggccga
     2461 atcattacct ggagcagtat ccccgaaagg ttgcctgtta cctcgccagc atcagtaaac
     2521 tggataactt tctcggtcag cttgatggta tccttcgccg gtattcccgt cattttgcca
     2581 tgctttactt ttctgaccat gggatgtcgg tcagcgacag tgctaatcct gttcatcatg
     2641 atggccatgt gcagggtggc tacagtgttc ccctgattat taccgccagt gacatcacat
     2701 ctcaccagtc cgtcagcaga aaaatcagtg cccgtcattt cgcaggcatt tttcagtggc
     2761 tgactggtat tcgtactgaa aatataccgc cattcaaccc gctgataaat gaagataatg
     2821 aaactgttat ggtttttaac ggagagaaaa tagttcctgc ggacggcctt aagtcacagc
     2881 ctgtgattct tccgggcaag ggaaaataag agtaatgttg agcaccatgt tctgtacgat
     2941 gaattttcca ctgtttatat cgattatttt gctaataacc agagttgagc acccgaaaat
     3001 acctgaagag gaattacccg ctaccaggag gttcagatat ccctgatgtc ggctataaaa
     3061 attttgatta catgacgtaa tggaagtggt tctgtcaatt gccttgttta ttcattaatc
     3121 tcaaagaaaa aggtattgaa aataattccc gggctggcag cccgggatga ttactatttt
     3181 aatggattgt taatctttgc atattcaaac gggctgatac attgttctct gttcgcatcc
     3241 agaaaatctg cccaccactg tagcatcagt cgccgttctt ccagatgttc tgctttatga
     3301 atgtaagcag cacgtacacc gttacgttcc tgatggctca tctgacgttc aactgcatcg
     3361 cgggaccaca aacctgattc tattaacgca ctacatgcca tcgcccggaa tccatgacca
     3421 cagacatcct gggttgtgtc ataccccata accctcaggg ctttatttac ggtgttttca
     3481 ctgattggtt tacgtgggtc atgtgctccc gtaaagatca gaccattttc accagcccat
     3541 gtctgaagtt ctgccagtat ggctacaacc tgtttgctga gtggcacaag atgtggtgtt
     3601 cgcatcttgg atccccggtg tgagaatttt acgcctggca gaggttcgcg ttcggctgga
     3661 atagtccaca tggaattgtc aatatcaatt tccgaccagc gggcatatct gagttcactg
     3721 gaacgaataa aaaccagtaa attcagcata actgccagtc gggtgacagg ctggccttta
     3781 taactgtcaa tacgcgacag aagttcaggc aggcgtgaaa gctccagagc agggcgatgc
     3841 tggcgtttta ccgtggtcaa tgcaccagcc atatccagag ccgggttata tctgatgatg
     3901 ccagactgta cggcgtaacg cattacagca gatattcttt gctgcagacg actggcgatt
     3961 tcataaattt gttttgcttc tgcagcacga acagggataa gcaggtccgg ggtattgagt
     4021 gttgtgatat cccggttgcc gataaagggg aaaacgtgtg tctcgaggct tttgagtact
     4081 ttatcgctgt gtgattgtgc ccattgttta ttactggcat gccagcgtcg tgcaatatgt
     4141 tcaaaagaga gctgtaaatc agggacaact tttttaactc ttttctgttc gcaagggtca
     4201 atcccctctg aaatcagttt tcgggcctca tcccgttttg tacgagcttc ggagagagaa
     4261 acttctggat acacaccaag tgccagagtc ttctccttac ccagaatacg ataacggaga
     4321 cgccagtaac gggaaccatt aggatgaacc agcaggaaca tgccggcccc gtcagtgagt
     4381 ttataagcct tgtcagtggg ctttgcagcc cggatttttg cgtcagtcag tgccatagtt
     4441 cagccttctg aatgcgttaa agagggtaca aattctgtcg aactggggta tacccgcaat
     4501 tatacccaca caatgaggtt gatgtgggga gaatttggtt gagttcggta gaattgattt
     4561 ggaggaagaa cacttaaatc atggtgttct gaaacgaaaa acggacctcc gtggaggtcc
     4621 gttgatatga atttggtgcc cggactcgga atcgaaccaa ggacacgggg attttcaatc
     4681 ccctgctcta ccgactgagc tatccgggca acggggcgca ttaaacctga ttcgcctcgt
     4741 ctcgtcaatc aaatttcttc aatttactgc agactgcaca atctatcatc actttgccgc
     4801 tattgcacgc attgtcaggc aaaccaggcg gtccaggcgg cggaaagcgg cattgccaga
     4861 aggagtgctg gaagcatgtt gaccaccggg aacattttaa tgccacagat gcgtaatccg
     4921 gttgccagca gcaataaacc gcctacggcg ctgaagtctg ccatcatcga cggtgtggtc
     4981 agcggtaata tcagcgcggc agcccacgcc agcgttaact ggatgatcag taatgggata
     5041 ctaattaccg acaccgcaat acccagcgag caggcgaaga tcatcgccgt aaagaaatca
     5101 agaaatgact tggcgattaa aatactcgga tcgccggtca tcccttcgtt catcgccccg
     5161 aagatcccgg tgccgctggc gcaaaacagg acaataatcg cgacataatt ctgaataaaa
     5221 gattcatgcg ctggcttctt acgtgagtga cgaaacagat tttgtgcttt ggcgactgct
     5281 gtattgacac ctttctccag caaacaaatt tcgccaatta gagcgccaag tagcgtagct
     5341 aaaaccatcg ctggaaggtt ggcgcatttc acaaccagta aaataccaat ccccagcgat
     5401 gccagaccaa aaatagatgt catggagacg cggatacgtt ccggtaagcg ttggctgagc
     5461 agtgcgccga gaacgccacc cagtaagact gcactagcgt tgataaaagg gccgatgacc
     5521 acaagagttc ctgttagctg tattgtttga ttttcttatt atgaactttt tgccttgttg
     5581 atggcttgtc tggtcgcaaa gtcctggctt gcacgcttta gcgaaaggtg ccatgattgc
     5641 gcgaattttc tcctctctgt acggagtttg cccgatgcac gccatctcct tacattctct
     5701 cgcttatcgc cgtttcgcgc gaaactcttc tctttttatg ctactgctca tgcggtgaag
     5761 ttaacgcacg ttcactgcag gacaacagta aaatcagagc gtttctgctt ttactgatgt
     5821 ctggcggtcg gagctggtga ccagtttgac ccatatctca tggggcaggg ttttccacct
     5881 tgtccggtat tcttacttcc ccgaaacggg tttgcgctta tgaaatcaat gaatattgcc
     5941 gccagtagtg aactggtatc ccgactttct actcatcgcc gcgtggtggc gttgggagat
     6001 actgatttta cggacgtcgc ggcagtcgtc attaccgctg cggatagtcg cagtggcatt
     6061 cttacgttgc ttaagcgcac cggttttcat ctaccggtgt ttttgtattc cgaacatgct
     6121 gttgaattac ctgcgggcgt tacggcggta atcaacggca acgagcagca ttggctggag
     6181 ctggaatccg cagcctgtca gtatgaagag aatttgctgc caccgtttta tgacacgctg
     6241 acgcagtacg ttgagatggg caacagcacc tttgcttgcc ctgggcatca acatggtgcg
     6301 ttttttaaaa agcatcctgc cggacgccat ttttacgatt tctttggtga gaacgtcttt
     6361 cgcgccgata tgtgtaatgc tgacgtaaaa ttgggcgatc tgcttattca tgaaggatcg
     6421 gcgaaagatg cgcagaaatt cgcagccaaa gtctttcatg ccgataaaac ctattttgtg
     6481 ctgaacggca catcggcagc gaataaagtg gtgacgaatg cgctgttaac gcgtggcgat
     6541 ctggtgctct tcgaccgtaa caaccataag tcgaatcatc acggcgcgct gattcaggcg
     6601 ggggcgacgc cggtctatct ggaagcttca cgcaacccgt ttggtttcat tggcggtatt
     6661 gatgcgcact gttttaatga agagtatctg cgccagcaaa ttcgcgacgt tgcgccagaa
     6721 aaagccgacc tgccgcgccc gtttcgcctg gcgattattc agctgggaac ctatgacggc
     6781 actgtctata acgcccgtca ggtgatcgat accgttgggc atctgtgtga ttacattctg
     6841 tttgattccg cgtgggtcgg ttatgaacaa tttatcccga tgatggcgga tagctcgccg
     6901 ctgctgttag aacttaacga aaacgatccg gggatttttg tgacccagtc ggtgcacaaa
     6961 cagcaggctg gattctcaca gacgtcgcag atccataaaa aagataacca tatccgcgga
     7021 caggcgcgtt tttgcccgca taagcggttg aataacgcct ttatgctcca tgcttctacc
     7081 agcccgttct acccgctgtt tgccgcgctg gacgttaacg ccaaaattca tgaaggggag
     7141 agtgggcgtc ggctgtgggc tgagtgcgtt gagttgggta ttgagtcgcg caaggctatt
     7201 cttgcgcgct gtaagctgtt ccgcccgttt atcccccccg ttgttgatgg caaattgtgg
     7261 caggattatc cgacatcagt gttagccagc gaccgccgtt ttttcagttt tgagccgggg
     7321 gcgaagtggc acggctttga aggatatgcc gcggatcagt attttgttga tccgtgcaag
     7381 ctgttactca ctacaccagg tatcgatgcc gaaaccggcg aatatagcga ctttggcgtt
     7441 ccggcgacga ttctggcgca ctatctgcgt gagaacggca ttgtgccgga gaagtgcgat
     7501 ctcaactcca ttctgttctt attaactccg gcggaaagcc acgagaagct ggcacaactg
     7561 gtggcgatgc tggcgcaatt tgaacagcat attgaggatg actcgccgct ggctgaggtg
     7621 ttgccgagcg tttataacaa atatccggtg cgctatcgcg actacaccct gcgccagttg
     7681 tgtcaggaga tgcacgatct gtatgtcagt ttcgacgtca aagacctaca aaaagcgatg
     7741 ttccgccagc agagtttccc gtcagtggtg atgaaccccc aggatgcgca tagcgcttat
     7801 attcgcggtg acgtggagtt ggtgcggatt cgtgatgccg aagggcgaat tgcggcagaa
     7861 ggggcgttgc cttatccacc tggcgtgctt tgcgtggtac ccggggaagt ctggggtggg
     7921 gcggttcaac gttatttcct tgcactggaa gaaggggtga atttgttgcc gggattttcg
     7981 ccggagctgc aaggtgttta tagcgaaacc gatgcggatg gcatgaaacg gttgtacggt
     8041 tatgtgttga agtaagaata aaaaaaacgg gtcaccttct ggcgacccgt ttttctttgc
     8101 gtaattagtg gctaaccgtc tgtgtacctg tcgggacacg aacgtgttta tatttgaaca
     8161 tcgccatgaa cgcgaaggcc agaaccacgg agtaaccagc gaaaatcaac catacggtct
     8221 gccagtcggt aatgccgttt tgggtgtaca tctcaaccac tttaccgctc acgatgccac
     8281 cgaggataca gccgaagccg ttggtcatca tcaggaacat cccttgcgca ctggcgcgaa
     8341 tcgccgggct aacttctttt tcgacaaaca ccgaaccaga gatgttgaag aagtcgaacg
     8401 cacagccgta aacaatcatc gacagaacca gcagtacggt gccgaacgga gtcgggtcgc
     8461 cgtaagcaaa cagcgcaaaa cgcaggatcc acgccacgat actgatcatc attacgttct
     8521 taatgccgta gcggcttaag aagaacggga tggtcagaat gaacagggtt tcagagatct
     8581 gcgaaatcga catgatgatt gacgcatgct gcacaataaa gctgctggca aacatcggat
     8641 ctttgtcgaa gctgtgcagg aaggtattac cgaacatgtt ggtaatctgc agttccgcgc
     8701 ccagcagcat tgagaagatg aagaagattg ccatacgctt gtttttaaac agcgcgaatg
     8761 catcgaggcc cagcagggtt gtccagctct gattcgcttg ctgtttagca accggaatat
     8821 gcggcagagt cagggtaaac agaaccagaa tggcggaaag agctgcgcca atatacagct
     8881 gcatgtggct taattcgaag ccagacaggc tcaccaccca cattgccatg ataaagccga
     8941 tggtgcccca gatacggatt ggtgggaagt cagtaacgat atccatcccg gcattttgca
     9001 ggcgatagta agagatggtg ttgattaacc caagcgttgg catataagca aacgagttaa
     9061 tcaatatcac aaggaacatc gcctccggcg tcgtgacctg tgctgccatg aacagcgtga
     9121 tagcgccaat ggtgtggcaa atggcatata cccatttcgc acttaaccat ttgtcggcca
     9181 caatccccag cagcgcaggc ataaagaccg cggcgatacc cagtgagcta taaactgcgc
     9241 caatagaagc accgtcaaac ttcagggtaa caaacatata ggagccgagg gtcgtcagcc
     9301 aacttcccca cagacagaac tgcagaaaag agaggatttt cagctgcagc ttaagattca
     9361 tgttaatttc ctcacatcgt gatgcggatg agtgtttgaa aaagcacatt tgaccgtgcg
     9421 agatgatggg attctatcaa cttcgcggac tggttttttg ttacctgtgg caaataattg
     9481 caaacattcc caatttgcaa aacgaaattg tgatgtggat aacatttttg cccctgagca
     9541 tcgtcagggg cggttaatgg aattatcggc ggcggtagga tttttgcgcg gtattcactt
     9601 tataaagata acggcgagat tccgcagagg gatggcgggt cgtcagcgtc tgataaacat
     9661 cgcccggcgt catggtgtta ataatattgg cagcctgaat cttatcattc gaaaagactc
     9721 gcagcacgct gcctgcgccg ccgttatagg cggtgatgac ggcataacgc cgcgatgttg
     9781 ggttatcaat tccgccgaga taaacattgt tcagcatcgc cagatacgcg gtgccggtat
     9841 caatattgct ggcaggatca aacaagaaac tgcggctcgg cgtgccggat ttcccctgcg
     9901 agcggaacac atctttcccg gcagtatgtt gtaccacctg cattaatccc agcgcatcgg
     9961 aacggctgac cgcatacggg ttaaaggaag attcggtctg cataattgcc agaatcagcg
    10021 actcatcaac gccatatttc cgtgacgcct ggcggaccat gccgagatat ttgtgcgcac
    10081 gtttatcaag gtggttcggt accatgttaa tggtgacgct gtagatgata cgcagcccgt
    10141 tactgcggct ttgcagacgg tttttcagca gataatccgc gaagttgctt gcgcgacctt
    10201 cccagcgaat cggctgcccg gtgttgtcca ccacctgacc gtaaaggaaa ggttctttcg
    10261 aaatcgtaat atcatcaacg tcggaataga gatcgaccga actcggatcg tcacccatca
    10321 ataacgtttt gataattgcc cggcgcaaat gcgcggcagg ttctgtcccg gcgatggttt
    10381 cgatagtaat cgtaccgtca tcgaagttga tgtggctgcg ggtctgatat tgatcggtgt
    10441 atttcacgta gtccttagga ccagcgatca ccacctcttt gaatccccag atgttctcaa
    10501 tattgtgggc aaattgcccc atcagaatat caaaaccgtt ggtgtctttg acccaggctt
    10561 cgttataggt atcgcctttt ttggtcgtcg aacaggagat gagcaacggc gcaatcaaag
    10621 ccagcgcgag atattttttc atcattccgg gtgcgtgttg tgtttgtttt tatgcaagtt
    10681 gccggaggcg tgctccggca ctgtttttat tttttatctt ccggcgtata gccctcgata
    10741 tgcacctctt taccctcgaa caggaagttg accatctcct gctccagcag cttgcggtgc
    10801 tcggcattca tcatgttgag tttcttttca ttaatcagca tggtttgttt gtgctgccac
    10861 tgcgcccagg cttctttgga gatctcgtta tagatgcgtt ttcccagctc gccggggtac
    10921 agctgaaaat cctgaccttc tgcttcacgt tgcaggaaag tacaaaaaat cgttctgctc
    10981 ataaatcatc ctctttatcg gctcacgcgc taaaccggcg cgccagtgcg taactgctgt
    11041 aacaaacgct ccacgggagc cgccaggcca actgacggcg gttgcgctaa gttataccag
    11101 agcgcattgc cttcatccat gcagccggtg aatgacgaca cgggaagcca cataggcaca
    11161 atatctaagt ggaaatggct gaaggtatgg cgaaacgcgg tcagctgcgt caggttatcg
    11221 gcagcaatct gccgttgcgc cagccaatgc cgcaaacttt cttcgtcggc aaactgcggg
    11281 aaacagtata aaccgcccca caatccgctc ggcggacgct gcgccagcaa tacttcatct
    11341 tcgtgctgta atagcaaaaa gtagccggtg cgctccggca gcgtctgttt cggttttttg
    11401 cccggataaa gcgcccagct attgttggcg gcggcaatac atccgttttg tagcggacag
    11461 agcgaacatt tcggtttcga gcgcgtacaa atcatcgcac ccaaatccat catcgcctga
    11521 ttaaaccgtt ccacgccgac cgcgggcgtc acctgctcgc ttaaactcca taatttattc
    11581 tcgacctctt ttttcccagg ccagccgctt acagcatagc agcgcgccag cacgcgtttg
    11641 acgttaccgt cgagaatcgg aaagtgctta cccagagaaa gcgagagaat cgcgcctgcg
    11701 gtggaacgcc cgacgcccgg cagtgctgca acttcctcaa aggtttccgg gaatttaccg
    11761 ccgtgtaagg tcgccacttg ttgtgccgct ttatgcagat tgcgcgcgcg ggcgtaatag
    11821 ccaagcccgg tccacaagtg gagaacttcg tcgagcggcg cattggcgag atcggtcacc
    11881 gtcgggaagc gcgccataaa gcgttcaaaa taggggataa cggtcgcaac ctgagtttgt
    11941 tgcaacatca cttctgagag ccatactttg tagggcgtct tgtcaatttg ccagggcaga
    12001 gtttttcgcc cgtatttatc gtaccagtcc agaacctggg ctgaaaattg cgacgcttgc
    12061 atggtcaccg aattcactgt tgttgggggc aagattgcag cacagcgacg gcagggtgta
    12121 aaccggaact ttccgcagcc acggccttat catgcttgca tccggcaact aactttggat
    12181 aatgcccgtt ttcagaacac tttcacaagc gactaaatct ttatgaaaaa cgacgtcatt
    12241 tcaccggaat ttgatgaaaa cggccgccca ctgcgccgta tccgtagttt tgtgcgccgc
    12301 caggggcgac tgaccaaagg ccaggaacat gcgctggaaa actactggcc ggtgatgggc
    12361 gttgagttca gcgaagatat gctggatttc cccgcgcttt ttggccgtga agcgccggtg
    12421 acgcttgaga ttggttttgg catgggggcg tcgctggtgg caatggctaa agatcgcccc
    12481 gagcaggact tcctcggcat tgaagtgcat tcaccgggcg ttggtgcgtg cctggcttct
    12541 gcgcatgaag agggcttaag caacctgcgc gtgatgtgtc acgatgcggt tgaagtgctg
    12601 cataaaatga ttcctgacaa ttcattgcgc atggtgcagc tctttttccc tgacccgtgg
    12661 cacaaagcgc gccataataa acgccgtatc gttcaggtgc cgtttgccga actggtaaaa
    12721 agcaaactgc agctgggggg cgtattccat atggcgaccg actgggaacc ttatgcggaa
    12781 catatgcttg aagtgatgtc ttctattgac ggttataaaa acctgtcaga gagcaatgat
    12841 tacgtaccgc gtccggcatc acgtccagtg acgaaatttg aacaacgtgg tcatcgtctt
    12901 ggtcacggag tatgggactt aatgttcgag agggtgaaat aatggcaaag aaccgtagcc
    12961 gtcgtctgcg taaaaaaatg cacatcgacg aattccagga attaggattt tcggtggcat
    13021 ggcgattccc ggaaggtaca tcggaagaac agattgataa aaccgttgat gattttatta
    13081 acgaggttat cgaaccgaac aaactggcct ttgacggcag cggttatctg gcctgggaag
    13141 gtctgatctg catgcaggaa atcggcaaat gcaccgaaga acatcaggca attgtgcgta
    13201 agtggctgga agagcgcaaa ctggatgagg tacgcaccag cgaacttttc gacgtttggt
    13261 gggactaaga aagcatacgg gcgatgacaa atgcaaaact gcctgatgcg ctacgcttat
    13321 catgcctgga aagatgcacg atcgagtagg ccggataagg cgtttacgcc gcatccggca
    13381 tggaaaacgc gtactttgtt atcaatctgg ggccagcaaa tgctggcctg atttgttctt
    13441 gagggaagac tatgatgcgc aaaatgctgc tggcggcagc actttcagtg acggcaatga
    13501 ccgctcacgc cgactaccag tgcagcgtca cgccgcgtga cgatgtgatt gtcagcccgc
    13561 aaaccgtgca ggtgaagggc gaaaacggca atctggtgat cacgccagac ggcaacgtga
    13621 tgtataacgg taagcaatat tccctgaatg ccgcccagcg cgagcaggcg aaggattatc
    13681 aggctgaact acgcagcacg ctgccgtgga ttgatgaagg cgcgaaaagc cgcgtcgaaa
    13741 aagcccgtat tgcgctggat aaaattatcg ttcaggagat gggcgaaagc agcaaaatgc
    13801 gcagccgtct gaccaaactt gatgcgcagc tgaaagagca gatgaaccgc attatcgaaa
    13861 cgcgcagcga tggcctgacg tttcactata aagccattga tcaggttcgc gccgaaggcc
    13921 agaaattagt gaatcaggca atgggtggaa ttttacagga cagcattaat gaaatgggcg
    13981 cgaaagcggt gctgaaaagc ggcggtaacc cattacagaa tgtgctggga agcctggggg
    14041 ggctgcaatc ctcaatccaa accgagtgga aaaagcagga aaaagatttc cagcagtttg
    14101 gcaaagatgt ttgtagccgc gttgtgactc tggaagatag ccgcaaagcc ctggtcggga
    14161 atttaaaata atcctctatt ttaagacggc ataatacttt tttatgccgt ttaattcttc
    14221 gttttgttac ctgcctctaa ctttgtagat ctccaaaata tattcacgtt gtaaattgtt
    14281 taacgtcaaa tttcccatac aaagctaagg gataatgcgt agcgttcacg taactggagg
    14341 aatgaaatgg agtttttcaa aaagacggca cttgccgcac tggttatggg ttttagtggt
    14401 gcagcattgg cattacccaa tatcaccatt ttagcaaccg gcgggaccat tgccggtggt
    14461 ggtgactccg caaccaaatc taactacaca gcgggtaaag ttggcgtaga aaatctggtt
    14521 aatgcggtgc cgcaactgaa ggacattgcg aacgttaaag gtgagcaggt agtgaatatc
    14581 ggctcccagg acatgaacga taatgtctgg ctgacactgg cgaaaaaaat taacaccgac
    14641 tgcgataaaa ccgacggctt cgtcattacc cacggtaccg acacgatgga agaaaccgct
    14701 tacttcctcg acctgacggt gaaatgcgac aaaccggtgg tgatggtcgg cgcaatgcgc
    14761 ccgtccacgt ccatgagcgc agacggtcca ttcaacctgt ataacgcggt agtgaccgca
    14821 gctgataaag cctccgctaa tcgtggcgtg ctggtggtga tgaacgacac cgtactggac
    14881 ggtcgcgatg tcaccaaaac caacaccacc gacgtagcga ccttcaagtc tgttaactac
    14941 ggtcctctgg gctacattca caacggtaag attgactacc aacgtacccc ggcacgtaag
    15001 cacaccagcg atacgccatt cgatgtctct aagctgaatg agctgccgaa agtcggcatc
    15061 gtttataact acgctaacgc atccgatctt ccggctaaag cactggtaga tgcgggctat
    15121 gatggcatcg ttagcgctgg tgtgggtaat ggtaacctgt ataaatccgt gttcgacacc
    15181 ctggcaaccg ccgcgaaaaa cggcactgca gtagtgcgtt cttcccgcgt accgacgggt
    15241 gctaccactc aggatgctga agtggatgat gcgaaatacg gcttcgtcgc ctctggcacg
    15301 ctgaacccgc aaaaagcgcg cgtcctgctg cagctggctc tgacgcaaac caaagatccg
    15361 cagcagatcc agcagatctt caatcagtac taatcacctc gccccggtat cgtgccgggg
    15421 ctttttcact tcagacttac gtccattgcc aattttcatt accctaatga taatcaccgg
    15481 aataaattat tccgcgtgag gtttttcggg tgaaaaagca atggattgtt ggcacggcac
    15541 tgcttatgtt gatgactggt aatgcttggg cagatggcga accgccaact gaaaatatct
    15601 taaaagatca attcaaaaag cagtatcacg gcattctcaa gcttgatgct atcaccttaa
    15661 aaaatcttga tgctaagggt aatcaggcca cctggtcagc ggaaggcgat gtctcttcca
    15721 gtgacgatct ctatacctgg gtcggtcagt tggcagatta cgaactgctc gaacagacct
    15781 ggacgaaaga taaaccggta aaattctcgg cgatgttaac cagtaaagga acgcccgcgt
    15841 ctggctggtc ggtgaacttt tactcttttc aggcggcagc cagcgatcgt gggcgggtgg
    15901 tcgacgatat caaaacgaat aataaatatc tgatcgtgaa tagcgaagat ttcaattatc
    15961 gctttagtca gcttgaatct gcgttgaata cccagaagaa ctcgattcct gcgctggaaa
    16021 aggaagtgaa agcgcttgat aagcaaatgg tggcggcgca gaaagcagcg gatgcatatt
    16081 ggggaaaaga tgcaaacggt aagcaaatga cccgcgaaga agcctttaaa aaaattcacc
    16141 aacagcgtga tgagtttaat aaacagaacg atagcgaggc gttcgcggtt aaatatgaca
    16201 aagaggttta tcaaccggcg attgcggcat gtcataaaca gagtgaagag tgttatgaag
    16261 tgccgattca gcagaaacga gatttcgata tcaacgaaca acggcgacag acttttctgc
    16321 aatcacaaaa actcagccgt aaattgcagg atgactgggt aacgctcgaa aaagggcaat
    16381 atccgttaac gatgaaagtt tcagaaataa acagtaaaaa agtcgcgatt ttgatgaaaa
    16441 ttgacgatat caaccaagct aatgaacgct ggaaaaaaga taccgaacaa ctgcggcgca
    16501 atggggtgat taagtaagtt tgatatagtg cacgatttgt agcaggatgc ggcgttgacc
    16561 ccgcatccgg caatcaacgt ctgatgcgac gcttgcgcgt cttatcagac ctacaaccgt
    16621 tgccacatgt aggctggata aggcgttcac gccgcatccg gcaatacaag tttactcagc
    16681 cagaaaaagc tccagcagcg aatttaaaaa cagcttccca tgttccgtta tctgccagta
    16741 atccgcacat tcggtgagat aaccctgggc aatcgcctcg tctaactgtg ggcgaatcac
    16801 atcttcgcaa agcccggtat acgcaataaa ctccacgcgc ggcgcggcct ccagcagacg
    16861 gaagcgattc ataaagaact caaacggctt atctgcggct tcgacatcac gctggctttc
    16921 cagatacctt ccctgcataa aaccacgcgg atgacgcgtt ttggtggtac gcagaatgcg
    16981 cccatccggg aaggtcactt tgccgtgcgc gccacagcca ataccgatgt agtcgccaaa
    17041 tcgccagtag ttgagattgt gctggcactg ataaccgggt ttggcgtaag cggaagtttc
    17101 atattgctga taacccgctg cggttaataa ctgatgcccc tgttcgaaaa tatcccacag
    17161 cgcgtcatcg tccggcagca ccggtggtcg cgaaccaaac agcgtattgg gttcgatggt
    17221 cagttgatac caggaaagat gcggcggatt cagttcaatg gcctggcgta gatcgccaag
    17281 cgcctcttcc agtgattgat ccggtagtcc atgcatcaaa tcaaggttaa agctacgtaa
    17341 ccctaaaccg ctcgccagct ttgccgctcg tttcgcttct tgcgggccat gaatgcgccc
    17401 gagtcgtttc agcttttctt cgctaaaact ctgcacacca atagagatgc ggttcacacc
    17461 agcacgctga taatcgacaa agcgatccgc ttctaccgtg cctgggttcg cttccatagt
    17521 aatttctgca tccgctgcca gcggcaaacg cgcacgcacg ccgtccagca gcgtttgcat
    17581 cgccgggccg gaaagcaggc tcggcgtacc accgccaata aagattgtct ttacttcacg
    17641 gccctgagcg taagccacat cgttgtccag atcgttaagc agatgctgaa cataatcgtc
    17701 gtgcggcact tctcctttca acgcgtgaga gttgaaatcg cagtacgggc atttctgcac
    17761 gcaccacggg atgtgaatgt agagactcag cggcggtaat ttaaccatta cgtaaagcgt
    17821 ccagcagcag tttcaatgcc tgaccacggt gggaaatggc gctcttttct tcgcgggtca
    17881 gttcggcggc ggttttccct tcggaaggta cgaagaagat tggatcataa ccaaagccac
    17941 cagtgcccgc tggttcacga gtaatcacgc ccggccagct accgtggcat accagcggag
    18001 tcggatcttc cgcgtgacgc agatatacca gcacgcagtg gaaacgcgcc tgacgttggt
    18061 catccggtac gtctttcagt gtttccagca gtttttgcag attctttaga tcggtcgcgt
    18121 cttcaccgga ataacgcgcg gagtaaatgc ccggcgcgcc gccaagcaca tctaccgcca
    18181 gaccagagtc gtcggcaatt gccggtaaac cggtcacttt tgccgcatgg cgcgctttca
    18241 gaatcgcgtt ttcgataaag gtcaggccgg tttcttcagc ggaatctacg ccgaggtctg
    18301 tttgggccac gatatcaaga ccgaagtcgc taagcagcga cgccagctca cgcactttac
    18361 cggcattgcc ggttgcgagg acaacttttt gcataggata cctaattaat taacgccgcg
    18421 atttctggcg ggatttgttg cggattaatg attttaattt gtttgtggcg gccaagttcg
    18481 cctttttcaa tcaccacctg gcttttggca acccggaatt gcttaccgag aaacttcacc
    18541 agatgactgt tggcctgacc gtcaaccggc ggcgcggtaa tggcgacttt aacttcgtcg
    18601 ccatgtaaac cgacaataga atcacggctg gctttcggct gaatatagag ccgtaaaacc
    18661 agaccgtcat cattaactgt tacggcactc ataacgccat ccacagcccc ggcagcagca
    18721 tgtttccggt tgcctgtaat acttctgcga cacccatatt gatgacatac agcagcagaa
    18781 cgaggatcat cggcgagaaa tcaatcccac ccattgccgg tagcaggcgg cgaatcgggc
    18841 gcagcagcgg atcggccagc tgaatcagca cgtattcaat cgggctacga ccctggctta
    18901 cccagctcat aatcgccatc accagcagga cccagaaaat cagcaggccg atggttttca
    18961 gcagaatcag taaaccggca atccagatga ttggcaggaa ggtcaccact ttaaacagca
    19021 cgatggcttt gataaaactg agaatatagg caaccagcag cgaggcgctg tcaatggggc
    19081 ccattgccgg aataacgcgg cgcagtggcc cgataattgg ctgcgttacc ttcactacaa
    19141 actgtgagaa ggggttgtaa aaatcacaat gagcccactg catccagatg cgtaataaca
    19201 gcaccatggt atacagctca atgaccgttg aaagcaggaa agtcaacgta ttcatggcgt
    19261 tcctttaatt ccttattttt tagagtaatc acgcgcacca aaaattgcag tgccgatacg
    19321 aaccatcgtg ctacctgccg caatggcggc ttccatatcg tccgacattc ccagagagag
    19381 cgtgtcgata tgcgggtagc gcgttttcag tccggcaaat gctacagcca tttggcgtgc
    19441 aacttcaaac tgccttacat attctgactc aggtgcaggg attgccatca gcccgcgcag
    19501 acgtaaacgc ggtagttcag cgaccgcagc tgccagctcg tccagttctg ccagttgaat
    19561 cccggactta ctgttttcat cactaatatt aatttgaatc agtacgttaa gagggggaag
    19621 ttctgccggg cgctgatcgt tgaggcgggt agcgatgcgc aaacggtcga tggtatgaca
    19681 ccagtcgaaa tgctctgcca ccaggcggct tttattagac tgcaacgggc caataaaatg
    19741 ccattctaat cctgttacgc ccagttcctg aaagtggcga attttatcca ccccttcctg
    19801 aacgtagttt tcaccaaatt gacgctgccc ggcatcaatg gcttctgcga tggcgctcgc
    19861 aggttttgtt ttactgactg caagcagcgt aatttcttct ggagaacggc cgcaacgcgt
    19921 tgcagccgct gagattttgt cccggacctg tgccaggtta tgcgcaatat cgttcatttt
    19981 ccgaggatct tagtatgaat atggaagaaa ttgtggccct tagtgtaaag cataacgtct
    20041 cggatctaca cctgtgcagc gcctggcccg cacgatggcg cattcgcggc agaatggaag
    20101 ctgcgccgtt tgatgcgccg gacgtcgaag agctactgcg ggagtggctg gatgacgatc
    20161 agcgggcaat attgctggaa aatggccagc tggattttgc cgtgtcgctg gcggaaaacc
    20221 agcggttgcg tggcagtgcg ttcgcgcaac ggcaaggtat ttctctggca ttacggttgt
    20281 taccttcgca ctgtccacag ctcgaacagc ttggtgcgcc accggtattg ccggaattac
    20341 tcaagagcga gaatggcctg attctggtga cgggggcgac ggggagcggc aaatctacca
    20401 cgctggcggc gatggttggc tatcttaatc aacatgccga tgcgcatatt ctgacgctgg
    20461 aagatcctgt ggaatatctc tatgccagcc agcgatgttt gatccagcag cgggaaattg
    20521 gtttgcactg tatgactttc gcatcggggt tgcgggctgc attgcgggaa gatcctgatg
    20581 tgattttgct cggagagctg cgtgacagcg agacaatccg tctggcactg acggcggcag
    20641 aaaccgggca tttggtgctg gcaacattac atacgcgtgg tgccgcgcag gcagttgagc
    20701 gactggtgga ttcatttccg gcgcaggaaa aagatcccgt acgtaatcaa ctggcaggta
    20761 gtttacgggc cgtgttgtca caaaagctgg aagtggataa acaggaagga cgcgtggcgc
    20821 tgtttgaatt attgattaac actcccgcgg tggggaattt gattcgcgaa gggaaaaccc
    20881 accagttacc gcatgttatt caaaccgggc agcaggtggg gatgataacg tttcagcaga
    20941 gttatcagca gcgggtgggg gaagggcgtt tgtgacgttg ccatgcccga tgcgcaagtt
    21001 tatagggcct ataaaggcaa taaatgtctg atgcgacgct aacgcgtctt atcag
//
LOCUS       DAPGUL010000079        20871 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.080, whole genome shotgun sequence.
ACCESSION   DAPGUL010000079 DAPGUL010000000
VERSION     DAPGUL010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20871
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.080"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(144..815)
                     /gene="queE"
                     /locus_tag="RHX21_003102"
     CDS             complement(144..815)
                     /gene="queE"
                     /locus_tag="RHX21_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="HDV1988254.1"
                     /translation="MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTW
                     EKLEDREVSLFSILAKTKESDKWGSASSEDLLAVIGRQGYTARHVVITGGEPCIHDLL
                     PLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYDVLSQALERANEIKH
                     PVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHK
                     YLNIA"
     gene            988..1590
                     /locus_tag="RHX21_003103"
     CDS             988..1590
                     /locus_tag="RHX21_003103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000944219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HDV1988255.1"
                     /translation="MLRTFIVIIFIFNLSGCGYNDIQTYDEQVNASWSEVLNQYQRRA
                     DLIPNLVASIKGYSNHEKDVLEAVTLARSQANRASSDLQQTPGNEQKLQAWQQAQAQV
                     TRTLGQLTIISERYPELKAQELYQNLMVQLEGSENRIAVARGRYIKAIEQYNVTIRKF
                     PAVLTAKVMDYTPKKNYLPDDVAAVSKAPTIDFSQNASAH"
     gene            1604..2509
                     /locus_tag="RHX21_003104"
     CDS             1604..2509
                     /locus_tag="RHX21_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001479509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgcG family protein"
                     /protein_id="HDV1988256.1"
                     /translation="MKNLILLLVLICSSAFAVQVPVPEFAKYINDLTGTLTREEVSTL
                     TSQIKTLTQKSHAQLIVLVVETTGDETIEQYATRVFERWQPGHKNLDDGILLVVAWQD
                     HTVHIEIGYGLEGILTDAQSGQIIRNSIIPAFKKGDLAVGLQQGIGDIETRLSENDLV
                     NNTSPDHPLPFSGWWALLVWAIVLTFISARGYVKTLGVICFAAIILAFVLPIAGYSGS
                     WGVLATLLCFATPFLVVAIAFTPFGRKVRDSMRSANRPSRYERSNSASRHSSSSSSSS
                     SSSFNNDNFSGGGGSSGGGGASGRW"
     gene            2545..2907
                     /locus_tag="RHX21_003105"
     CDS             2545..2907
                     /locus_tag="RHX21_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988257.1"
                     /translation="MSKILANHPRLSKFVFGLFGAAGMIWLNKAFQGDELFQLITSLL
                     ALDTFVYFCIYSLINPIPEANDFLWDYKVHQRKYSSNISHNDFVSNVRNSRKIVRILI
                     LVGITFINVIALLTKLKM"
     gene            complement(2963..4261)
                     /gene="eno"
                     /locus_tag="RHX21_003106"
     CDS             complement(2963..4261)
                     /gene="eno"
                     /locus_tag="RHX21_003106"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HDV1988258.1"
                     /translation="MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTG
                     SREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTEN
                     KSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHA
                     DNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGS
                     NAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHF
                     LEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKG
                     IANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQI
                     KTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQA"
     gene            complement(4349..5986)
                     /gene="pyrG"
                     /locus_tag="RHX21_003107"
     CDS             complement(4349..5986)
                     /gene="pyrG"
                     /locus_tag="RHX21_003107"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase (glutamine hydrolyzing)"
                     /protein_id="HDV1988259.1"
                     /translation="MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPY
                     INVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRK
                     ERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQM
                     AVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPA
                     NERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEW
                     EQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVE
                     TRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARH
                     VANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVD
                     DSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPW
                     FVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK"
     gene            complement(6214..7005)
                     /gene="mazG"
                     /locus_tag="RHX21_003108"
     CDS             complement(6214..7005)
                     /gene="mazG"
                     /locus_tag="RHX21_003108"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HDV1988260.1"
                     /translation="MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVL
                     DAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFAD
                     SSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWT
                     TLGPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQK
                     ANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL"
     gene            complement(7076..7411)
                     /gene="mazF"
                     /locus_tag="RHX21_003109"
     CDS             complement(7076..7411)
                     /gene="mazF"
                     /locus_tag="RHX21_003109"
                     /EC_number="3.1.27.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease MazF"
                     /protein_id="HDV1988261.1"
                     /translation="MVSRYVPDMGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTG
                     MCLCVPYTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLI
                     KAKINVLIG"
     gene            complement(7411..7659)
                     /gene="mazE"
                     /locus_tag="RHX21_003110"
     CDS             complement(7411..7659)
                     /gene="mazE"
                     /locus_tag="RHX21_003110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin MazE"
                     /protein_id="HDV1988262.1"
                     /translation="MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLII
                     EPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW"
     gene            complement(7737..9971)
                     /locus_tag="RHX21_003111"
     CDS             complement(7737..9971)
                     /locus_tag="RHX21_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HDV1988263.1"
                     /translation="MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQ
                     QTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKS
                     VVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHL
                     REVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLL
                     HERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDV
                     RAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTV
                     EIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGE
                     MLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVP
                     FTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAG
                     RQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNK
                     PSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGF
                     ITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRD
                     ITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARR
                     LHGS"
     gene            complement(10019..11320)
                     /gene="rlmD"
                     /locus_tag="RHX21_003112"
     CDS             complement(10019..11320)
                     /gene="rlmD"
                     /locus_tag="RHX21_003112"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDV1988264.1"
                     /translation="MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKALFIPGL
                     LPQENAEVTVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQR
                     SKSAALARLMKHEVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVK
                     QCPILVPQLEALLPKVRACLGSLQAIRHLGHVELVQATSGTLMILRHTAPLSSADREK
                     LERFSHSEGLDLYLAPDSEILETVSGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVA
                     RALEWLDVQPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNARLNGLQ
                     NVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPA
                     TLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK"
     gene            11377..14133
                     /gene="barA"
                     /locus_tag="RHX21_003113"
     CDS             11377..14133
                     /gene="barA"
                     /locus_tag="RHX21_003113"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase BarA"
                     /protein_id="HDV1988265.1"
                     /translation="MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDA
                     GASIIEPLAVSTEYGMSLQNRESIGQLISVLHRRHSDIVRAISVYDENNRLFVTSNFH
                     LDPSSMQLGSNVPFPRQLTVTRDGDIMILRTPIISESYSPDESPSSDAKNSQNMLGYI
                     ALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRR
                     GQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQN
                     VELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTI
                     ERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTL
                     NIKSDVPDNVIGDPLRLQQIITNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIR
                     DTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNR
                     GSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETPLEVVYS
                     PTFSALPPAHYDMMLLGIAVTFREPLTMQHERLAKAVSMTDFLMLALPCHAQVNAEKL
                     KQDGIGACLLKPLTPTRLLPALTEFCHHKQNTLLPVTDESKLAMTVMAVDDNPANLKL
                     IGALLEDMVQHVELCDSGHQAVERAKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQ
                     QTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPE
                     VNEIVVNPNATLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENPEGL
                     VDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGTKEEDLEPELLELLDEMDNVAREAS
                     KILG"
     gene            complement(14365..15705)
                     /gene="gudD"
                     /locus_tag="RHX21_003114"
     CDS             complement(14365..15705)
                     /gene="gudD"
                     /locus_tag="RHX21_003114"
                     /EC_number="4.2.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucarate dehydratase"
                     /protein_id="HDV1988266.1"
                     /translation="MSSQFTTPVVTEMQVIPVAGHDSMLMNLSGAHAPFFTRNIVIIK
                     DNSGHTGVGEIPGGEKIRKTLEDAIPLVVGRTLGEYKNVLTLVRNTFADRDAGGRGLQ
                     TFDLRTTIHVVTGIEAAMLDLLGQHLGVNVASLLGDGQQRSEVEMLGYLFFVGDRKAT
                     PLPYQSQPDDSCDWYRLRHEEAMTPDAVVRLAEAAYEKYGFNDFKLKGGVLAGEEEAE
                     SIVALAQRFPQARITLDPNGAWSLNEAIKIGKYLKGSLAYAEDPCGAEQGFSGREVMA
                     EFRRATGLPTATNMIATDWRQMGHTLSLQSVDIPLADPHFWTMQGSVRVAQMCHEFGL
                     TWGSHSNNHFDISLAMFTHVAAAAPGKITAIDTHWIWQEGNQRLTKEPFEIKGGLVQV
                     PEKPGLGVEIDMDQVMKAHELYQKHGLGARDDAMGMQYLIPGWTFDNKRPCMVR"
     gene            complement(15726..17066)
                     /locus_tag="RHX21_003115"
     CDS             complement(15726..17066)
                     /locus_tag="RHX21_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucarate dehydratase"
                     /protein_id="HDV1988267.1"
                     /translation="MTTQSSPVITDMKVIPVAGHDSMLLNIGGAHSAYFTRNIVVLTD
                     NAGHTGIGEAPGGEVIYQTLVDAIPMVLGQEVARLNKVVQQVHIGNQAADFDTFGKGA
                     WTFELRVNAVAALEAALLDLLGKALNVPVCELLGPGKQRDAITVLGYLFYIGDRTKTD
                     LPYLENTPGNHEWYQLRHQKAMNSEAVVRLAEASQDRYGFKDFKLKGGVLPGEQEIDT
                     VRALKKRFPDARITVDPNGAWLLDEAISLCKGLNDVLTYAEDPCGAEQGFSGREVMAE
                     FRRATGLPVATNMIVTNWREMGHAVMLNAVDIPLADPHFWTLSGAVRVAQLCDDWGLT
                     WGCHSNNHFDISLAMFTHVGAAAPGNPTAIDTHWIWQEGDCRLTKNPLEIKNGKIAVP
                     DAPGLGVELDWEQVQKAHEAYKRLPGGARNDAGPMQYLIPGWTFDRKRPVFGRH"
     gene            complement(17068..18420)
                     /gene="gudP"
                     /locus_tag="RHX21_003116"
     CDS             complement(17068..18420)
                     /gene="gudP"
                     /locus_tag="RHX21_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate/glucarate/glycerate transporter
                     GudP"
                     /protein_id="HDV1988268.1"
                     /translation="MSSLSQAASSVEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGS
                     EMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLDRFGSKRVYFWSIFIWSMFTLLQ
                     GFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQY
                     FATVIFAPIMGWLTHEVGWSHVFFFMGGLGIVISFIWLKVIHEPNQHPGVNQKELEYI
                     AAGGALINMDQQNTKVKVPFSVKWGQIKQLLGSRMMIGVYIGQYCINALTYFFITWFP
                     VYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRRTGSLNIARKTPIVMGM
                     LLSMVMVFCNYVNVEWMIIGFMALAFFGKGIGALGWAVMADTAPKEISGLSGGLFNMF
                     GNISGIVTPIAIGYIVGTTGSFNGALIYVGVHALIAVLSYLVLVGDIKRIELKPVAGQ
                     "
     gene            complement(18855..19304)
                     /locus_tag="RHX21_003117"
     CDS             complement(18855..19304)
                     /locus_tag="RHX21_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDV1988269.1"
                     /translation="MAEIGIFVGTMYGNSLLVAEEAEAILTAQGHKATVFEDPELSDW
                     LPYQDKYVLVVTSTTGQGDLPDSIVPLFQGIKDSLGFQPNLRYGVIALGDSSYVNFCN
                     GGKQFDALLQEQSAQRVGEMLLIDASENPEPETESNPWVEQWGTLLS"
     gene            complement(19322..20104)
                     /gene="truC"
                     /locus_tag="RHX21_003118"
     CDS             complement(19322..20104)
                     /gene="truC"
                     /locus_tag="RHX21_003118"
                     /EC_number="5.4.99.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(65) synthase TruC"
                     /protein_id="HDV1988270.1"
                     /translation="MLEILYQDEWLVAVNKPSGWLVHRSWLDRDEKVVVMQTVRDQIG
                     QHVFTAHRLDRPTSGVLLMGLSSEAGRLLAQQFEQHQIQKRYHAIVRGWLMEEAVLDY
                     PLVEELDKIADKFAREDKGSQPAVTHYRGLATVEMPVATGRYPTTRYGLVELEPKTGR
                     KHQLRRHLAHLRHPIIGDSKHGDLRQNRSGAEHFGLQRLMLHASQLSLTHPFTGEPLT
                     IHAGLDDTWMQALSQFGWRGLLPENERVEFSAPSGQDGEISS"
     gene            complement(20104..20433)
                     /locus_tag="RHX21_003119"
     CDS             complement(20104..20433)
                     /locus_tag="RHX21_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqcC family protein"
                     /protein_id="HDV1988271.1"
                     /translation="MTTHDRVRLQLQALEALLREHQHWRNDEPQPHQFNSTQPFFMDT
                     MEPLEWLQWVLIPRMHDLLDNKQPLPGAFAVAPYYEMALATDHPQRALILAELEKLDA
                     LFADDAS"
BASE COUNT         5201 a         5548 c         4930 g         5192 t
ORIGIN      
        1 aattaatgcc acagaatttg tagagaatgc taatgattag ccctggatgg gtaaaatgga
       61 ggagttttca gaggcgacaa acaatataaa tgagtagaag tctttacagg ttccacccat
      121 ttataacgct tataaatgtt taatcaggca atatttagat atttatgtgt ttgcatcgac
      181 aaacgccaat tacgcgcaat gcaggtttca atgcacaaac gtgtggcatc atccttttgg
      241 ctaatcggct gcagtgcaat gactcgcggt ttatcatcgg tcagcgttgc caatagttca
      301 tccagtgctt caatatcgcg tacgcgcccc actggatgct tgatttcgtt ggctcgctcc
      361 agtgcctgtg acaacacgtc atagccgccg cgcatgttca gctttggcga tacggtaacc
      421 caggtattcg gtgtgcagcg tacctcatga gtaccactgg tttcgatctg gcagctaaaa
      481 ccgttctttt cgagcagatc agtcagtggt agcaaatcat gaatgcaagg ctcaccaccc
      541 gtaatcacca catgccgcgc ggtgtatccc tggcgaccaa tgacagccag caaatcttca
      601 ctgctcgccg acccccactt atcactctct ttggtcttcg ccagaatgct gaaaagggag
      661 acttcccgat cctcaagctt ttcccaggtg tgtttggtgt cgcaccaggc acagccaacc
      721 gggcatccct gtaaacgaat aaaaatggcg ggaacgccgg taaagtaacc ctcaccttgc
      781 agggtctgga acatctcgtt aatcgggtac tgcatagcat tctctgtgaa gtggataatt
      841 gttaattatt gcagatcctg ccgcaacaat catgtcttat taacattctg ttacaggcag
      901 gtttaaggca aaaagtgcat tagatcataa agaataaaat gatgcgacgt attatgtttt
      961 aaggaattaa tgaaaaagga tttaaacatg ctcaggacat tcatcgtaat tatatttatt
     1021 ttcaatttat caggctgtgg atataacgat attcaaacct atgatgagca ggttaacgcc
     1081 tcctggtctg aggtattaaa tcaatatcaa cgtcgcgccg atcttattcc taatcttgtc
     1141 gccagtatta aaggttattc caaccatgaa aaagacgttt tggaagccgt aacattggct
     1201 cgtagccagg ctaatcgcgc cagcagcgat cttcagcaaa ctccgggaaa tgaacaaaaa
     1261 ttacaagcct ggcaacaggc tcaagcgcag gtgactcgca ctctcggtca gttaacgata
     1321 attagtgagc gttaccctga gttaaaggct caagagctct atcaaaactt aatggtacag
     1381 ctcgaaggaa gtgaaaatcg aattgccgtt gcgcgaggaa gatatattaa agccattgaa
     1441 caatataatg ttactatccg caaattcccc gctgtattaa ccgcaaaggt catggattac
     1501 acaccgaaga aaaattattt gccggatgat gtcgccgctg tgagtaaagc accaacaata
     1561 gattttagcc agaatgctag tgctcattag gcgagttaat tatatgaaaa atttaatctt
     1621 acttcttgtt ctgatctgtt catctgcgtt tgcagtgcaa gttccagtac ctgaattcgc
     1681 taagtatata aatgatttaa cagggacatt aaccagggag gaagtaagta cgctgaccag
     1741 tcagattaaa accctgacgc aaaaaagcca cgcacaactg atcgtgttag tagtagaaac
     1801 aacaggcgat gaaaccatcg agcaatatgc aacacgagta ttcgagcgtt ggcagcccgg
     1861 tcataagaat cttgatgacg gtattttact ggtagttgcc tggcaagatc atacagtaca
     1921 tattgaaatt ggctacggac ttgagggtat tctgacggat gcgcagtccg ggcaaattat
     1981 acgcaacagt attattcctg cgtttaaaaa gggcgatctt gctgtcggct tgcaacaagg
     2041 tattggtgat attgaaaccc gattatcaga aaatgattta gtcaataata catcgcccga
     2101 tcatccttta ccctttagcg gttggtgggc tctgttagtc tgggcgatag tactgacgtt
     2161 tatttctgcc agaggatatg tcaaaacgct gggagtgatt tgctttgctg ccataatact
     2221 ggcctttgta cttcccatcg ctggatatag cgggagctgg ggagttcttg ccacattatt
     2281 atgtttcgcc actccattcc tggtcgtagc tatcgctttc acgcctttcg gcagaaaggt
     2341 gcgtgattca atgcgtagcg ccaaccgacc gtcacgttac gaaagaagca actcggcctc
     2401 ccgacattct tcatcatcgt catcttcctc ttcatcctct ttcaacaatg acaatttcag
     2461 cggtggtggc ggttcatccg gcggtggcgg cgcgtcagga agatggtaag acttaaaaac
     2521 agattacagg gaaggtaagg aaatatgagt aagattttag cgaatcatcc acgattaagt
     2581 aaatttgtat ttggcttatt cggtgctgct ggaatgattt ggcttaataa agccttccag
     2641 ggcgatgaat tatttcaact gataacatca ctgcttgctt tagatacgtt tgtgtacttt
     2701 tgcatctaca gtctgattaa cccaatacct gaggcaaatg attttctttg ggattataaa
     2761 gtccatcaac gaaaatattc atccaatatt tctcataatg attttgtcag caatgtaagg
     2821 aatagcagaa aaattgttcg gatacttatc ctggtgggaa taacatttat taatgttatc
     2881 gctctgctta ctaaactcaa aatgtgaaga taaaaaaacc cgcttcaaga agcgggtttt
     2941 ttattaagac gttaagtcag tcttatgcct ggcctttgat ctctttacga ccgttgtacg
     3001 gtgctttttc gcccagagct tcttcgatac gaatcagctg gttgtattta gcaacacggt
     3061 cagaacggct catagaacca gttttgatct ggcctgcagc agtaccaaca gccaggtcag
     3121 cgatggtagc gtcttcagtt tcgccagaac ggtgagagat aactgcagtg tagccagcat
     3181 ctttcgccat cttgattgca gccagagttt cggtcagaga accgatctgg ttgaatttga
     3241 tcaggatgga gttagcgata cctttttcga taccttcttt caggatcttg gtgttggtta
     3301 cgaacaggtc gtcaccaacc agctggattt tgtcgcccag aactttggtc tggtatgcga
     3361 aaccgtccca gtcagattcg tccagaccgt cttcgataga aacgatcggg tactgtttgg
     3421 tcagttcttc caggaagtga gtgaattctt cagaggtgaa cgctttgttg ccttcgccag
     3481 ccagaacgta tttaccatct ttgtagaatt cagaagctgc gcagtccatc gccagagtga
     3541 tgtctttgcc cagttcataa ccagcagctt taacagcttc agcgataaca gccagagctt
     3601 cagcgttgga acccaggttc ggcgcatagc caccttcgtc accaacagca gtgttcatgc
     3661 ctttcgcttt cagaactttt gccaggtgat ggaaaacttc agaacccatg cggatggctt
     3721 ctttcacagt tttcgcgcca accggctgaa tcatgaattc ctggatatca acgttgttgt
     3781 cagcgtgctc accaccgttg atgatgttca tcatcggaac cggcatagag tatttgcccg
     3841 gagtaccgtt cagttcagcg atgtgctcgt acagcggcat acctttagca gctgcagcag
     3901 ctttggcgtt agccagagat acagccagga ttgcgttcgc gccgaatttg gatttgtttt
     3961 cggtgccgtc caggtcgatc atgatcttgt caatgccagc ctgatcttta gcatctttgc
     4021 caatcagcgc ctgagcgatc gggccgttta ccgcagcaac agctttggtt acgcctttac
     4081 ccaggaaacg ggatttgtcg ccatcgcgca gttccagagc ttcacgggaa ccagtagaag
     4141 cacctgacgg agcagctgcc ataccgacga aaccaccctc cagatgtact tcggcttcaa
     4201 cagtcgggtt accacgggag tcgatgattt cacgaccgat gatttttacg attttggaca
     4261 ttaggttttc ctcaagtcac tagttaaact gaaactccag acaaacaacg cgtacccagg
     4321 gtacgcgttg ccgttctaac ttttttactt acttcgcctg acgcttctgg aactcgctgg
     4381 cggcttttac aaagccagca aacagcgggt gaccatcacg tggagtagaa gtaaactccg
     4441 gatggaactg gcaagccacg aaccacgggt gattcggaac ttcgatgatc tcgaccaact
     4501 gatcatcccc ggaacggccc gcaacgcgca gacctgcatc ttcaatctgt ttcaacagca
     4561 tgttgttgac ttcgtaacgg tgacgatgac gctcaacaat tgtcggcgca ttgtacagct
     4621 ggcgaaccag gctatcgtca accaactggc actgctgtgc gccgagacgc atggtaccgc
     4681 cgagatcgct cttctcgcta cgaacttcaa cgttgccgtt ttcatcgcgc cactcggtaa
     4741 tcagcgccac aaccgggtac ttacagtctg gcacaaattc cgtagagttg gcgttctcca
     4801 tgttggcaac atggcgagcg taatcaatta acgccacctg catacccagg caaatgccca
     4861 gataaggaat attgttctca cgcgcaaaac gcgcggtcgt aatcatgcct tctacgccac
     4921 gatagccaaa accgccaggt actaggattg cgtccagacc tttaaggatt tcaacgccgc
     4981 gcgtttcaac atcttgtgaa tcgattagtt tgatgttgac gctgacacga ttcttcagcc
     5041 caccgtgttt cagtgcttcg atcactgatt tataagcatc cggcagttca atgtacttgc
     5101 cgaccatacc gatggtgact tcacttaccg ggttcgcttc ttcgaagata acctgttccc
     5161 attcggacag attcgcttcc gggcagttta agctgaatcg tttacaaata taatcgtcca
     5221 gcccctgaga tttcaacagg cccggaattt tatagatgga atcgacgtct ttcagagaaa
     5281 taaccgcttt ttccggaaca ttacagaaca atgcaatctt cgcacgttcg ttcgccggaa
     5341 cagcgcgatc tgaacgacaa atcaggatgt caggctggat accgatggag agcagctctt
     5401 ttacagagtg ctgagtcggt ttggttttga cttcaccaga cgctgccatg tacggcacca
     5461 gcgtcaggtg cataaacaga gtgtgctcac ggccaatttc aacagccatc tggcgaatcg
     5521 cttcgaggaa cggcaaggat tcgatatcac ctactgtacc gccgatttct accagtacta
     5581 cgtcatgacc ttcgccacct tccagcacgc gctctttgat tgcgttagtg atgtgcggaa
     5641 taacctgcac ggttgcgccg aggtagtcac cgcggcgttc tttacgcaga acgtcagagt
     5701 agatacgacc cgtggtgaag ttgttgcggc ggctcatttt ggtacgaatg aaacgctcgt
     5761 agtgccccag gtccaggtcg gtttcagcgc cgtcttcagt aacgaacact tccccgtgtt
     5821 ggattgggct catagtacct ggatcgacgt tgatgtacgg atccagtttc atgatggtca
     5881 cattgaggcc acgggcttca agaatggctg cgagggaggc tgcggcaatg cctttaccca
     5941 gagaggatac gaccccgccg gtcacaaaaa tatagttcgt tgtcatgctg aacctgagaa
     6001 gttaggttga aaagacgatg gaataaccag gacgggaaag cagtataccc taacatgacc
     6061 tgtgccacaa actttcatta tccctcctct tcgccagcgc actattgaaa tcaggagtga
     6121 gaaaatagcc cctttggggt aaatgttttt gacgcaaatc aagcgcttgt catttaaaaa
     6181 atgacacaaa tggcgcttga ccgcgtaatt cccttagaga tcaatttcct gccgttttac
     6241 ctgttgccag acttcttcca ttgtttcgag gtcaacacct gtcatttcca gtccacgcgc
     6301 ggcaacaata cgctccactt cgcgaaaacg acgctcgaat ttttcgttcg ctttttgcaa
     6361 tgcgatttct gctttcgtcc ctaaatggcg agccagatta accgtggcaa acagcaggtc
     6421 ccccatttcc tcctccagtt tagcctggtc gacaacagcc tgccgcgcct cgtacatcac
     6481 ctcgtcgatc tcttcgtaga ctttatcaac caccgggcca agcgtcgtcc agtcgaagcc
     6541 aacgttggcg caacgtttct ggattttttg cgcccgcatt aaagccggta aactacgagg
     6601 aatatcgtcc agcgccgaat gctgcgcttt ctgcgcgcgc tcttcggttt tgatttgctc
     6661 ccaacgggca agcacttcac tactgttttc ggcagaacta tcagcaaaaa catgcggatg
     6721 gcgacgctct aatttatcgc taatagcagc gcaaatatca ttaaagtcaa agcgcccttc
     6781 ttcctgagcc atttgcgcgt aaaacaccac ctggaatagc agatcgccca gttcaccgcg
     6841 aagatcgtca aaatcttcac gggcgatggc gtccagcact tcgtaggttt cttcaagggt
     6901 gtaaggcgca atggtggcaa atgtctgctc tttatcccac gggcagccgt tttccggatc
     6961 gcgcaggcgc tgcataatag tgagcaaacg gtcgatttga ttcattgaat tgtcctgaaa
     7021 attgcgggtc tgtcaggtgg aaacctgtga ccagaataga agtgagttag taacactacc
     7081 caatcagtac gttaattttg gctttaatga gttgtaattc ctctggggca actgttcctt
     7141 tcttcgttgc tcctcttgcc cgccaggcga tactttttac ctgatcagct aacgctacgc
     7201 catcacgttc ctgaccggat aaaacaactt cgaacggata tccttttgat tgcgttgtat
     7261 aaggaacaca cagacacata cctgttttgt tgttgtacat gaaaggactc aggacaacag
     7321 ctggacgatg tccagcttgc tcgctacctt ttgtcgggtc aaaatcaacc caaatcagat
     7381 cgcccatatc gggtacgtat cggcttacca ttaccagact tccttatctt tcggctctcc
     7441 ccagtcgata ttctcgtgga ggttttccgg cgtgatgtcg ttgaccagtt cagcaagcgt
     7501 aaatacgggc tctttacgca ctggctcaat aattaatttg ccatccacca ggtcaatctt
     7561 cacttcatca tcaatattca gattgagcgc ctgcattaac gtagccggga tccgcaccgc
     7621 cggtgaattt ccccaacgct ttacgctact gtggatcata accctttcct caaaccgcta
     7681 tcatatgtag atacagtata tatcaatcta cattgtagat acgagcaaat ttcggcctaa
     7741 ctcccgtgca accgacgcgc gtcgataaca tccggcacct ggttgagttt acccagcacg
     7801 cgccccagca cttgcaggtt gtaaatctca atggtcatgt cgatggtcgc cagttgctgt
     7861 ttggtgtcgc tacggctggc aacgccaagc acgttcacct tctcgttggc gagaatggtc
     7921 gtgatatcac gtaacaaccc actacgatca ttagccacca cgcggaccac cagcgaatat
     7981 ccggcggagt agctctcacc ccataccgcg tcaacaatgc gttctggcgc atgggagcgc
     8041 agttccgcca gttgttcgca atcggcgcgg tgtactgaaa taccgcgccc ctgggtaatg
     8101 aagccgacaa tctcatctcc aggaatcggc tggcagcagc gcgcgatgtg gtgcatcagg
     8161 ttaccgacac cttcaaccac cacgcgaccg ttatctttac tgcggttttg cggcgtgtag
     8221 cttttttgct gaagttgctt cagcgcggcg gcgtcctgct cttcggcact cggcttatta
     8281 aattgcgatt gcaggaagtt caccatctga ttgagacgga tatccccgcc accaatcgcc
     8341 gccagcaact cgtcgacatc attaaagttg taacgcggca gcagatgttt ttctgcttct
     8401 ttcaggctga tccccagatg ttccagctcg tcgtcaagga tttgccgccc agccagaatg
     8461 tttttgtcac ggtcctgttt acggaaccag gcgtgaattt tcgaacgccc acggctggtt
     8521 gtgacgtaac cgaggtttgg gtttaaccag tcacggctgg ggttcggctg tttctgggtg
     8581 ataatttcaa tctggtcgcc catctgcagc tggtaggtga acggcacaat gcgcccgcca
     8641 atttttgccc cgatgcagcg gtgtccgaca tcactgtgga tgtggtaagc gaagtccagc
     8701 ggcgttgatc ccgcaggcaa atcaacgaca tcacctttcg gcgtaaagac atacacccgg
     8761 tcgtcaaaga cctggctgcg tacttcgtcg agcatttcgc cggaatcagc catctcttcc
     8821 tgccacgcaa tcagtttacg cagccaggca atccggtctt catgtcccga acgtgcgccg
     8881 ccagctgccg cgccctcttt atatttccag tgcgcagcaa cacccaactc tgcatcttca
     8941 tgcatctgtt tggtgcggat ttggatctca acggttttgc cacctggccc cagaaccacg
     9001 gtatgaatag actgataacc gtttggtttc gggttagcga cataatcgtc aaactcatcc
     9061 ggcaggtggc gatagtgagt gtgcactatc cccagtgcgg catagcaatc ctgtaaacgc
     9121 tcggcgacaa tacgtaccgc acgcacatca aacagctcat caaaggcgag gttctttttc
     9181 tgcattttac gccagatgct gtagatgtgt ttcggacgac catacacttc agctttaacg
     9241 ccttcagctt tcatctcagc gcgcagatga ccgacaaact cttcgatata gtgttcgcgg
     9301 tcgagacggc gttcatgcag cagttttgcg atgcgtttgt attcggtcgg gtgcagataa
     9361 cggaagcagt aatcttccag ctcccatttc agttgcccaa tcccaagacg gttcgccaac
     9421 ggcgcgtaga tattggtgca ctcttttgcc gccagtacgc gttcatcttc cggcgcatct
     9481 tttacttcgc gcagatgagc aatacgctcc gccagtttga tgaccacgca gcgaaaatca
     9541 tcgaccatcg ccaataacat ccggcgaacg ttatcgacct gttcggagga aacagaatca
     9601 gtgtgcgtcg ctttcagctg gcggatcgcc gccatatcac gcacgccgtg aataaggtta
     9661 acaaccgact taccgacgct ctcacgcagc acatcttcgc taactacgtt ggcatcagcc
     9721 agagggaaca gcagcgccgc ccgcagcgtg tcaatgtcca tacttaatgt cgagaggatc
     9781 tccaccatct caacaccacg ccacaataac agactggcat ccggatgccc ctgcgtctgt
     9841 tgcagacaat acgcccaggt ttcggctaag cactcacacg acttctggct ggtaataccc
     9901 agacttgcga tccatttttc cggatcaaat tcaccagcct tattgatatg tgcacttctt
     9961 accgcaacca tcgtcctctc ctttagggac cagacctgcc gaaatcggca aatcgtaact
    10021 atttaacgcg cgagaaaagt accatcgatt ccagatgtcc cgtgtgtggg aacatatcca
    10081 gcatcgccag tcgcgcaatg gtatatcctg cttttaataa cgcttcgcta tcccgagcca
    10141 gcgttgcagg attacaggat acataaacta tacgaatagg ttccagtttt ataatttgct
    10201 gcataacacc tgcggcacct gctcgcgcgg ggtccagcaa cactttatcg aagccgtttt
    10261 tcgcccacgg ctgctttgtg acatcttctt caagattttc gtgataaaac gtcacattct
    10321 gtaagccatt aagacgcgca ttctgctggc ctttttccac cagcgccgga acaccttcta
    10381 cacccaccac actggcagct tgtgtcgcca atggcagtgt aaagttgccc ataccgcaga
    10441 acagatccag tacgcgatct tcaggttgca catccagcca ttccaacgca cgcgctacca
    10501 ttttttggtt cacacccgca ttgacctgaa taaaatcgcg cgggctaaaa gttaagcgca
    10561 acccgtttga gtcataccag ggcatctcac cagagacggt ttcgagtatc tcactatcgg
    10621 gggcgagata cagatccagg ccttcagaat gcgaaaagcg ttccagtttt tcgcgatcag
    10681 ccgaacttag cggtgcggta tggcgcaaaa tcatcagcgt gccgctggtt gcctgtacca
    10741 gttcaacatg accaagatgg cgtatagctt gtaagctgcc caggcatgcc ctgactttgg
    10801 gcagcaatgc ttcaagttgg ggcactaaaa tggggcattg tttgacgtcg acaatgtcac
    10861 tggagcccgc tttgcgaaag cccatctgaa gttgctgtgt tttcggtaag tagttcaaac
    10921 ttaaacgcgc gcgacggcga tagccccagg gaacatcggc gatcacttca gagacttcgt
    10981 gtttcattaa tcgggcgagt gccgcacttt tgcttcgctg ctgtaaatcc acgctggcgt
    11041 gttgttgctg acagccaccg catacgccaa aatgagggca gcgtggcgtt tcgcgttccg
    11101 ggctatcgct taaccggcgc acgactttag cgcgggcgta ctgtttttta tcttcagtaa
    11161 cagtaacttc cgcgttttcc tgtggcagta atccaggaat aaataacgct ttgccgttat
    11221 gtcgcgccac gccctgacca aaagagtcga ggtcgttgac tgaaacggtt atgatctgac
    11281 gcgtcgtcgt gcgtcgtttt gcagagtaga attgcgccat tggcgagact ttctcaattt
    11341 aacagtgtga ccttaattgt cccataacgg aactccatga ccaactacag cctgcgcgca
    11401 cgcatgatga ttctgatcct ggcaccgacc gtccttattg gtttattgct gagtatcttt
    11461 ttcgtcgtgc atcgctataa cgacttgcag cgtcaactgg aagatgccgg tgccagcatt
    11521 attgagccgc ttgcagtttc tactgaatat ggcatgagcc tgcaaaatcg cgaatctatc
    11581 ggtcagttaa taagcgtact gcatcgtcgc cattccgata ttgttcgcgc gatttcggtt
    11641 tatgatgaaa ataaccgact ctttgtcacc tccaattttc atcttgatcc ctcatcaatg
    11701 cagctcggca gcaacgtgcc gtttcctcgc cagctcactg tcactcgtga cggcgatatt
    11761 atgatcctcc gcacgccgat tatttctgag agttactccc ccgacgaatc gcccagtagc
    11821 gatgccaaaa atagtcaaaa tatgttggga tatattgcgc ttgagctgga tcttaaatcg
    11881 gttcgtttgc agcaatataa agagatcttt atttccagcg tgatgatgct gttttgtatc
    11941 ggtattgcgc ttatttttgg ctggcgctta atgcgcgatg taaccggtcc gattcgcaac
    12001 atggtgaata ccgtcgaccg catccgtcgc gggcaactcg acagccgggt ggaaggattt
    12061 atgctcggcg agctggatat gctgaaaaac ggtatcaact cgatggcaat gtcgctggct
    12121 gcttatcacg aagagatgca gcacaatatc gaccaggcga cgtccgatct gcgtgaaacg
    12181 ctggagcaga tggaaattca gaacgttgag ttagatctgg cgaaaaagcg cgcccaggaa
    12241 gcggcgcgta ttaaatccga gtttctggca aatatgtcac acgagctgcg tacaccactg
    12301 aatggtgtta ttggctttac ccgcctgacg ctgaaaacag aattaacacc aacgcagcgc
    12361 gatcacctga atacgattga acgttcggca aataatttgc tggcaattat taatgatgtt
    12421 ctcgacttct cgaaactgga agcaggtaag ctgattctgg aaagtattcc attcccacta
    12481 cgcagcacgc tggatgaagt cgttactctg ctggcacatt cttctcacga taaagggttg
    12541 gaactgacgc tcaatattaa aagcgacgtg cctgataacg tgatcggcga cccactgcga
    12601 ttacagcaaa tcatcactaa cctggtgggg aatgcaatta aattcaccga gaatggcaac
    12661 attgatattc tggtagaaaa acgtgcgctg agtaatacca aagtgcagat tgaagtgcag
    12721 attcgggata ccggcattgg tattcctgaa cgcgatcaat cgcgcttatt ccaggccttc
    12781 cgacaggctg atgccagtat ttcccgccgt catggtggca ccggtctggg gctggtgatt
    12841 acacaaaaac tggttaatga aatgggcggc gatatttcgt tccatagcca gccgaatcgc
    12901 ggttcaactt tctggttcca cattaatctc gatctgaacc cgaacattat tatcgaaggg
    12961 ccatccaccc agtgcctcgc cggtaagcgc ctggcctatg tcgaaccaaa ctccgcagca
    13021 gcgcaatgca cgctggatat tttaagtgaa acgccgctgg aagtggttta tagcccaacg
    13081 ttctccgcgc tgcctcccgc gcattacgac atgatgttgt taggcatcgc ggtgaccttc
    13141 cgcgagccgc taacaatgca acatgagcga ttagcgaaag cggtatcgat gaccgatttc
    13201 ctgatgctgg cacttccttg ccatgcacaa gtcaatgcag aaaaactcaa gcaagatggt
    13261 atcggcgcgt gtctgctgaa accattaaca cctacgcgcc tgttgcctgc cctgacggaa
    13321 ttttgtcatc acaaacaaaa cacgcttttg cctgtaaccg atgaaagcaa gctggcaatg
    13381 acagtcatgg cagttgatga caaccccgct aacctgaaac ttatcggcgc attgctggaa
    13441 gatatggtgc aacatgtgga actttgcgat agcgggcatc aggcggttga acgggcgaaa
    13501 cagatgccgt tcgatttgat cttaatggat attcaaatgc ctgacatgga tggcattcgg
    13561 gcctgcgagc tcatccacca gctcccccat cagcaacaaa cgccggttat cgcggtaacg
    13621 gcgcatgcaa tggccgggca aaaagagaag ctgcttggcg cagggatgag cgattatctg
    13681 gcgaaaccga ttgaagaaga gcgattgcat aatttgttgt tgcgctacaa gcctggcagc
    13741 ggtatttcct ctcgcgtcgt gacgcccgaa gtcaacgaaa ttgtggtgaa cccgaatgcg
    13801 accctcgact ggcaactggc actacgccag gcagcaggaa aaaccgattt agcgcgcgat
    13861 atgctgcaaa tgttactcga tttcctgcct gaagttcgca acaaagttga ggaacagctg
    13921 gttggagaaa acccggaagg cctggttgat ttgattcata aactgcatgg cagttgcggc
    13981 tatagcggtg tgccgcgtat gaagaatctc tgccaactga tcgaacaaca gctacgtagc
    14041 ggtactaaag aagaagattt ggagccggag ctgctggaac tgttggacga gatggataat
    14101 gtagcgcgcg aagccagcaa aattctcggg taacggacgt cttgtcgagt agcaatcggc
    14161 tttttatgac gctggtttca gattggtgac aaagtgcctg tgtttatgcc ggatgcggcg
    14221 ttaacgcctt atccggccta caaaaccaat taaattcaat gaattaaaaa atgatgtaga
    14281 cctgatacat agcacaacag gctattttgc gtttagcatc agtctcaagc cggctccaga
    14341 tagagccggt tttggttttc tgtcttaacg caccatgcac gggcgcttgt tatcgaacgt
    14401 ccagccagga atcagatact gcattcccat cgcatcgtca cgcgcgccaa gcccgtgttt
    14461 ctgatacagc tcatgggctt tcatcacttg atccatatcg atttctacac ccagccccgg
    14521 tttttccggc acctgaacca gaccgccttt gatctcaaac ggttctttgg tcaggcgctg
    14581 attaccttcc tgccagatcc agtgcgtatc aatagcagta attttacccg gtgcagcggc
    14641 ggcaacatgg gtaaacatcg ccagggaaat atcgaagtgg ttgtttgagt gtgaacccca
    14701 ggtcaggcca aattcatggc acatttgcgc cacacgtacc gaaccttgca tcgtccagaa
    14761 atgcggatcc gccagcggga tatcaacgga ttgcagggag agcgtatggc ccatctgccg
    14821 ccagtcggtg gcgatcatat tggttgcggt cggcaggcca gttgcgcgac ggaactctgc
    14881 catcacttca cgcccggaga aaccttgctc cgcaccacac ggatcttctg cataagccag
    14941 cgaccctttc aggtatttac caattttaat cgcttcgttc agcgaccagg caccgttagg
    15001 atcgagcgta atacgcgcct gcgggaagcg ttgcgccagt gccacaatag actcggcctc
    15061 ttcttccccg gccagtacac cgcctttcag tttgaaatcg ttgaagccat atttttcata
    15121 cgccgcttcc gccaggcgca ccaccgcatc cggcgtcatc gcttcttcat gacgcaggcg
    15181 ataccagtcg catgagtcat ccggctggct ttgatacggc agcggtgtgg ctttgcgatc
    15241 accgacgaag aacagataac cgagcatttc gacttcgcta cgctgttgac catcgcccag
    15301 cagcgatgcc acgtttaccc ccagatgctg ccccagcaga tccagcattg ccgcttctat
    15361 cccggtaact acatgaatag tggtacgcaa atcaaatgtc tgcaaaccgc gcccgccggc
    15421 atcacgatcg gcaaatgtat tacgcaccag cgtcagaacg tttttgtatt cacccagcgt
    15481 tctacccacc accagcggaa tcgcatcttc cagcgtttta cggattttct cgccgccggg
    15541 aatttcgcct acgccggtgt gaccggaatt atctttgata atcacaatat tacgcgtgaa
    15601 gaacggtgcg tgtgcaccac tcagattcat cagcatactg tcatgacccg ccaccgggat
    15661 gacctgcatt tcagtaacaa caggcgtcgt aaattgagaa ctcatattta tgtccttttt
    15721 cagaatcaat gacggccgaa aacgggacgt ttacggtcaa aggtccagcc ggggatcagg
    15781 tactgcatcg gacctgcgtc gttacgcgca ccgccaggca gacgtttata ggcctcatgt
    15841 gccttttgta cctgttccca gtccagttcc acgcccagac cgggcgcatc aggaacggca
    15901 atttttccgt ttttaatctc cagcggattt ttggtcaggc gacaatcgcc ctcctgccaa
    15961 atccagtggg tatcgatagc ggtaggatta cccggtgccg ccgcgcccac atgggtaaac
    16021 atcgccagag aaatatcgaa atggttatta gaatggcagc cccaggttag cccccagtcg
    16081 tcgcaaagct gtgccacgcg gactgcaccg gaaagcgtcc agaagtgcgg atcggcaagt
    16141 ggaatatcta ccgcattgag catcaccgca tggcccattt cgcgccagtt ggtgacgatc
    16201 atgttagtcg cgacgggcaa gccggtcgcc cgtcgaaact ccgccatcac ttcacgaccg
    16261 gagaaaccct gctcagcgcc gcacggatct tcggcatagg taagaacatc attcagccct
    16321 ttgcacaaag aaatggcttc atcaagcagc catgcaccgt tgggatcaac ggtaatccgc
    16381 gcatccggga agcgtttctt caatgcacga acagtgtcga tttcttgctc gccaggtaac
    16441 actccgccct taagtttgaa atctttaaag ccatagcgat cctgtgaggc ttccgccaga
    16501 cgcacaacgg cttcgctgtt catcgctttc tgatggcgca actgatacca ctcatggttg
    16561 cccggcgtat tttccagata aggaagatcg gttttggtcc gatcaccgat ataaaacaga
    16621 taaccgagga cggtaatagc atcgcgttgc ttgcctggcc ctaacagttc gcagaccgga
    16681 acattcaacg ccttacctag caggtcaagc aaggcggctt ccagcgccgc cacggcatta
    16741 acgcgcaatt caaaagtcca ggcacctttg ccgaaggtat caaaatcggc cgcctgatta
    16801 cctatatgca cctgctgaac cactttattc aggcgcgcaa cttcctggcc cagcaccatc
    16861 ggaatagcat cgacaagcgt ctgataaatc acctctccgc ccggcgcttc accaataccg
    16921 gtatgcccgg cattatcggt gagtaccaca atattgcggg tgaaatatgc gctatgtgca
    16981 ccaccaatat taagcaacat gctatcgtgc ccggcgaccg gaatgacttt catatcagta
    17041 ataacaggac tggattgtgt cgtcatctta ttgccccgcg acaggtttca gctcgatacg
    17101 cttgatatcg cccaccagca ccaggtagct cagtaccgcg attaaggcat gaacaccaac
    17161 ataaatcagc gccccattaa aggagccagt cgtgccaacg atataaccaa ttgcgattgg
    17221 cgtgacgatg ccagaaatgt taccgaacat gttgaacagg ccaccggaaa gaccgctgat
    17281 ctcttttggc gcggtatctg ccattactgc ccaacccagc gccccgatgc ccttaccgaa
    17341 gaaggccagc gccataaagc cgatgatcat ccactcaacg ttgacgtagt tgcagaacac
    17401 catcaccatc gacagcaaca tgcccattac gatcggtgtt ttacgcgcaa tgttcagcga
    17461 tcccgtgcgg cgcatcagcc agtcggaaat aatcccaccc agcacaccgc cgataaaacc
    17521 gcaaaccgcc ggaacggaag ccacaaagcc cgctttcaga atcgacatcc cacgcgcctg
    17581 caccagataa accgggaacc aggtaataaa gaagtaagtc agggcgttga tacagtactg
    17641 accgatataa acgccgatca tcatccgtga cccgagcagc tgtttgatct gcccccactt
    17701 cacgctgaac ggcactttaa ctttggtgtt ttgctgatcc atattgatca gcgcgccacc
    17761 cgcggcgatg tactccagct ctttctgatt tacccccgga tgttgatttg gctcgtggat
    17821 gactttcaac cagataaagc tgatgacaat ccccagaccg cccataaaga agaagacgtg
    17881 tgaccagccc acttcatgcg tcagccagcc cataatcggc gcgaagatca ccgttgcgaa
    17941 gtattgagcg gagttaaaaa tcgacaccgc cgttcccctt tcctgcgccg gaaaccaggc
    18001 cgcaacaatg cgactgttgc cggggaaaga tggcgcttca gcaagcccga ccaggaagcg
    18061 cagagtaaac agggcaacga taatgccgaa tccactaaag atatcgacga agccttgcag
    18121 caaggtaaac atcgaccaga taaagatcga ccagaagtag acgcgttttg aaccaaaacg
    18181 atccagcaac caaccaccag ggatctgccc gataacataa gcccatgaga aggcagagaa
    18241 cacatagccc attcccacgg gatcaaggcc gatatctttg gccatttccg aaccggcaat
    18301 agaaagcgta gcgcggtcgc cgtagttgaa ggatgtgacg ataaacaaca tcaccactat
    18361 ccagtaacga gcattcgtgc gtttttccac actgctcgca gcctgactta aagaactcat
    18421 tgttgcactc ctgaaaattc gcgttagcca cgctcactct ggactgcgac atagccagga
    18481 aatcagaggt gacgtagggt gttttttgcc gtttttatag gtcgttcgcc gaatacggcg
    18541 cgtgtttata tctggcaata gcagtataaa aagcgcgcca tagcggctca ccgtgcaaca
    18601 acacaacatt aatgcgttca atgaggcccg attttggcat tagccctgga cggtggaatc
    18661 cacttcacgg aaatgaaaac aagaacaaga aaggaagggt taaaacgaag aaataaagaa
    18721 gagtatgaaa tggatcgctt gactccaggc aaacgccagt aaaaatccgc gctatgaagc
    18781 agtttttact ggcatttgcc tgaaaatatt cgattcagca ccgctaaaac gacatttacc
    18841 gctcgctgaa catatcagga caacagcgtg ccccactgtt cgacccacgg atttgattcc
    18901 gtttccggtt ccgggttctc actggcgtca atcaacagca tttcgccaac ccgctgagcg
    18961 ctctgttcct gcaacaaggc atcgaactgt ttgccgccat tgcagaaatt tacataactg
    19021 ctgtcgccga gcgcaatcac gccataacgc agattcggct ggaagcccag actatctttg
    19081 attccctgaa agagcggcac aatgctatca ggaaggtcgc cctgcccggt cgtggacgta
    19141 accaccagaa catacttatc ctgatagggc agccagtcgc ttaattcagg atcttcaaat
    19201 accgttgctt tgtggccctg tgcggtcaga attgcttctg cttcttccgc cactaacagc
    19261 gaatttccgt acatggtgcc gacaaaaata ccaatttccg ccataccgtt ttctccctgg
    19321 attaggaact tatctctcca tcctgacccg atggcgcact gaactcaacc ctttcatttt
    19381 caggaagcag accgcgccag ccaaattgtg ataacgcctg catccaggtg tcgtccaggc
    19441 ccgcgtgaat agtcagcggc tcgccagtaa aaggatgcgt caatgacaac tgactggcat
    19501 gtagcattaa ccgctggagg ccaaaatgct cagcaccgct gcgattctgg cgtaaatcgc
    19561 catgtttgct atcgccaata atcggatgac gcaaatgggc aagatgtcgg cgaagctgat
    19621 gtttgcgtcc ggttttcggc tccagttcca ccaggccgta gcgcgtggtc gggtaacgtc
    19681 cggtcgctac cggcatttct acggtcgcca gaccgcgata atgcgtcact gctggctgcg
    19741 agcctttatc ttcgcgggca aatttatcag cgattttgtc cagttcttcc accagtggat
    19801 aatccagaac tgcttcttcc atcaaccagc cgcgcacaat cgcatggtaa cgtttctgga
    19861 tttggtgctg ttcaaactgt tgtgccagca gccgtccggc ctcgctggat aatcccatca
    19921 acaacacacc agaagtgggt cggtccagac gatgagcggt aaaaacgtgc tggccaatct
    19981 gatcacgcac ggtttgcatg accactactt tctcgtcgcg atccagccag ctgcggtgaa
    20041 ccagccagcc ggagggttta tttaccgcaa ccagccattc atcctgatag agtatttcca
    20101 gcattagctc gcatcatccg caaaaagagc atccagtttt tccagctcag ccagaataag
    20161 cgcgcgttgc ggatggtccg tcgccagcgc catttcataa tagggtgcaa cggcaaaagc
    20221 gcccggtaac ggctgtttgt tatctaacaa atcgtgcatt cgcgggatca gcacccactg
    20281 caaccactcc agtggttcca tggtgtccat aaagaacggt tgggtactat taaattgatg
    20341 cggctggggt tcatcgtttc gccagtgctg atgttcacgc agtaacgctt caagcgcctg
    20401 caactggaga cgaacgcggt catgagtggt cataaagcaa cctcaataag aaaaactgcc
    20461 gcgaaggata gcaggaataa aaaaagggag cactgtattc acagcgctcc cggttcgttt
    20521 cgcagcattc cagctacttt tgttgctccc tgctcatcct tgacaacttt tcctctggcc
    20581 ttgcggccaa tcgttcatcc tgaactattg cttcctgctc acaccacccc gatgtgatac
    20641 ttcatcctga agtgtccctg gccttcctga cccaccgaat catcctgacc ggttctcatt
    20701 ctccatcctg gaggtgtcct ttaacgcgtc ctgcgtcatc ctcttcgctt catccagaag
    20761 cctttccctg aaacaccatc ctggtgtgtc ctgcagaagt gtcatcatcc tgatgttcac
    20821 ttcgttgtct gactccctgt cgacgaagat agaatcgtct ttttcgcgaa g
//
LOCUS       DAPGUL010000080        20764 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.081, whole genome shotgun sequence.
ACCESSION   DAPGUL010000080 DAPGUL010000000
VERSION     DAPGUL010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20764)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20764)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20764
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.081"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(66..1715)
                     /gene="actP"
                     /locus_tag="RHX21_003120"
     CDS             complement(66..1715)
                     /gene="actP"
                     /locus_tag="RHX21_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation/acetate symporter ActP"
                     /protein_id="HDV1988272.1"
                     /translation="MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVV
                     FTLGITYWASKRVRSRSDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYD
                     GLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVAL
                     YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFG
                     ASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTA
                     GLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPEYKDAAG
                     HLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVF
                     KKGATEREELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLS
                     MYWSKLTTRGAMMGGWLGLITAVVLMILGPTIWVQILGHEKAIFPYEYPALFSISVAF
                     LGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH"
     gene            complement(1712..2026)
                     /locus_tag="RHX21_003121"
     CDS             complement(1712..2026)
                     /locus_tag="RHX21_003121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF485 domain-containing protein"
                     /protein_id="HDV1988273.1"
                     /translation="MNGTIYQRIEDNAHFRELVEKRQRFATILSIIMLAVYIGFILLI
                     AFAPGWLGTPLNPNTSVTRGIPIGVGVIVISFVLTGIYIWRANGEFDRLNNEVLHEVQ
                     AS"
     gene            complement(2226..4184)
                     /gene="acs"
                     /locus_tag="RHX21_003122"
     CDS             complement(2226..4184)
                     /gene="acs"
                     /locus_tag="RHX21_003122"
                     /EC_number="6.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase"
                     /protein_id="HDV1988274.1"
                     /translation="MSQIHKHTIPANIADRCLINPQQYEAMYQQSINVPDTFWGEQGK
                     ILDWIKPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDA
                     SQSKHISYKELHRDVCRFANTLLELGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHS
                     VIFGGFSPEAVAGRIIDSNSRLVITSDEGVRAGRSIPLKKNVDDALKNPNVTSVEHVV
                     VLKRTGGKIDWQEGRDLWWHDLVEQASDQHQAEEMNAEDPLFILYTSGSTGKPKGVLH
                     TTGGYLVYAALTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVP
                     NWPTPARMAQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRSSLRILGSVGEPINP
                     EAWEWYWKKIGNEKCPVVDTWWQTETGGFMITPLPGATELKAGSATRPFFGVQPALVD
                     NEGNPLEGATEGSLVITDSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDG
                     YYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHNIKGQAIYAYVTLN
                     HGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDTS
                     NLGDTSTLADPGVVEKLLEEKQAIAMPS"
     gene            4576..6012
                     /gene="nrfA"
                     /locus_tag="RHX21_003123"
     CDS             4576..6012
                     /gene="nrfA"
                     /locus_tag="RHX21_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-forming nitrite reductase cytochrome
                     c552 subunit"
                     /protein_id="HDV1988275.1"
                     /translation="MTRIKINARRIFSLLIPFFFFTSVHAEQTAAPAKPVTVEAKNET
                     FAPQHPDQYLSWKATSEQSERVDALAEDPRLVILWAGYPFSRDYNKPRGHAFAVTDVR
                     ETLRTGAPKNAEDGPLPMACWSCKSPDVARLIQKDGEDGYFHGKWARGGPEIVNNLGC
                     ADCHNTASPEFAKGKPELTLSRPYAARAMEAIGKPFEKAGRFDQQSMVCGQCHVEYYF
                     DGKNKAVKFPWDDGMKVENMEQYYDKIAFSDWTNSLSKTPMLKAQHPEYETWTAGIHG
                     KNNVTCIDCHMPKVQNAEGKLYTDHKIGNPFDNFAQTCANCHTQDKAALQKVVAERKQ
                     SINDLKIKVEDQLVHAHFEAKAALDAGATEAEMKPIQDDIRHAQWRWDLAIASHGIHM
                     HAPEEGLRMLGTAMDKAADARTKLARLLATKGITHEIQIPDISTKEKAQQAIGLNMEQ
                     IKAEKQDFIKTVIPQWEEQARKNGLLSQ"
     gene            6057..6623
                     /gene="nrfB"
                     /locus_tag="RHX21_003124"
     CDS             6057..6623
                     /gene="nrfB"
                     /locus_tag="RHX21_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418495.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase pentaheme
                     subunit"
                     /protein_id="HDV1988276.1"
                     /translation="MSVLRSLLTAGVLASGLLWSLNGITATPAAQASDDRYEVTQQRN
                     PDAACLDCHKPDTEGMHGKHASVINPNNKLPVTCTNCHGQPSPQHREGVKDVMRFNEP
                     MYKVGEQNSVCMSCHLPEQLQKAFWPHDVHVTKVACASCHSLHPQQDTMQTLSDKGRI
                     KICVDCHSDQRTNPNFNPASVPLLKEQP"
     gene            6620..7291
                     /gene="nrfC"
                     /locus_tag="RHX21_003125"
     CDS             6620..7291
                     /gene="nrfC"
                     /locus_tag="RHX21_003125"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase Fe-S protein"
                     /protein_id="HDV1988277.1"
                     /translation="MTWSRRQFLTGVGVLAAVSGTAGRVVAKTLNINGVRYGMVHDES
                     LCIGCTACMDACREVNKVPEGVSRLTIIRSEPQGEFPDVKYRFFRKSCQHCDHAPCVD
                     VCPTGASFRDAASGIVDVNPDLCVGCQYCIAACPYRVRFIHPVTKTADKCDFCRKTNL
                     QAGKLPACVEACPTKALTFGNLDDPNSEISQLLRQKPTYRYKLALGTKPKLYRVPFKY
                     GEVSQ"
     gene            7288..8244
                     /gene="nrfD"
                     /locus_tag="RHX21_003126"
     CDS             7288..8244
                     /gene="nrfD"
                     /locus_tag="RHX21_003126"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase subunit NrfD"
                     /protein_id="HDV1988278.1"
                     /translation="MTQTSAFHFESLVWDWPIAIYLFLIGISAGLVTLAVLLRRFYPQ
                     AGGADSTLLRTTLIVGPGAVILGLLILVFHLTRPWTFWKLMFHYSFTSVMSMGVMLFQ
                     LYMVVLVLWLAKIFEHDLLALQQRWLPKLGIVQKVLSLLTPVHRGLETLMLVLAVLLG
                     AYTGFLLSALKSYPFLNNPILPVLFLFSGISSGAAVALIAMAIRQRSNPHSTEAQFVH
                     RMEIPVVWGEIFLLVAFFVGLALGDDGKVRALVAALGGGFWTWWFWLGVAGLGLIVPM
                     LLKPWVNRSSGIPAVLAACGASLVGVLMLRFFILYAGQLTVA"
     gene            8264..9982
                     /locus_tag="RHX21_003127"
     CDS             8264..9982
                     /locus_tag="RHX21_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014640253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase CcmF/NrfE family subunit"
                     /protein_id="HDV1988279.1"
                     /translation="MDVFLPEVGFLALLLSLGVNVLTPLTAFAGVRLRWPAMMRLTCI
                     GILAQFALLLLAFGVLTYCFLISDFSVIYVAQHSYSLLSWELKLAAVWGGHEGSLLLW
                     VLLLSAWSALFAWHYRQQTDPLFPLTLAVLSLMLAALLLFVVLWSDPFVRIFPPAIEG
                     RDLNPMLQHPGLIFHPPLLYLGYGGLMVAASVALASLLRGEFDGACARICWRWALPGW
                     SALTAGIILGSWWAYCELGWGGWWFWDPVENASLLPWLSATALLHSLSLTRQREIFRH
                     WSLLLAIVTLMLSLLGTLIVRSGILVSVHAFALDNVRAVPLFSLFALISLASLALYGW
                     RARDGGPVVRFSGLSREMLILATLLLFCAVLLIVLVGTLYPMIYGLLGWGRLSVGAPY
                     FNRATLPFGLLMLVVIVLATFVSGKRVQLPALVAHAGVLLFAAGIVVSSVSRQEISLN
                     LQPGQQVTLAGYTFRFERLDLQAKGNYTSEKAIVALFDHQQRIGELMPERRFYEARRQ
                     QMMEPSIRWNGIHDWYAVMGEKTGADRYAFRLYVQSGVRWIWGGGLLMIAGALLSGWR
                     GRKRDE"
     gene            9975..10358
                     /gene="nrfF"
                     /locus_tag="RHX21_003128"
     CDS             9975..10358
                     /gene="nrfF"
                     /locus_tag="RHX21_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase NrfEFG subunit NrfF"
                     /protein_id="HDV1988280.1"
                     /translation="MNKGLLTLLLLFTCFARAQVVDTWQFANPQQQQQALNIASQLRC
                     PQCQNQNLLESNAPVAVSMRHQVYSMVAEGKNEVEIIGWMTERYGDFVRYNPPLTGQT
                     LVLWALPVVLLLLMALILWRVRAKR"
     gene            10355..10951
                     /gene="nrfG"
                     /locus_tag="RHX21_003129"
     CDS             10355..10951
                     /gene="nrfG"
                     /locus_tag="RHX21_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase NrfEFG subunit NrfG"
                     /protein_id="HDV1988281.1"
                     /translation="MKEPKIPVKMLTTLTILMVFLCVGSYLLSPKWQAVHAEYQRQRD
                     PLHQFASQQTPEAQLQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQL
                     RGENAELYAALATVLYYQASQHMTAQTRAMIDKALALDSNEITALMLLASDAFMQANY
                     AQAIELWQKVMDLNSPRINRTQLVESINMAKLLQRRSD"
     gene            11293..12606
                     /gene="gltP"
                     /locus_tag="RHX21_003130"
     CDS             11293..12606
                     /gene="gltP"
                     /locus_tag="RHX21_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate:proton symporter GltP"
                     /protein_id="HDV1988282.1"
                     /translation="MKSIKFSLAWQILFAMVLGILLGSYLHYHSDSRDWLVVNLLSPA
                     GDIFIHLIKMIVVPIVISTLVVGIAGVGDAKQLGRIGAKTIIYFEVITTVAIILGITL
                     ANVFQPGAGVDMSQLATVDISKYQSTTEAVQSSSHGIMGTILSLVPTNIVASMAKGEM
                     LPIIFFSVLFGLGLSSLPATHREPLVTVFRSISETMFKVTHMVMRYAPVGVFALIAVT
                     VANFGFSSLWPLAKLVLLVHFAILFFALVVLGIVARLCGLSVWILIRILKDELILAYS
                     TASSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGID
                     LSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMA
                     RTALNVVGNALAVLVIAKWEHKFDRKKALAYEREVLGKFDKTADQ"
     gene            complement(12684..13373)
                     /locus_tag="RHX21_003131"
     CDS             complement(12684..13373)
                     /locus_tag="RHX21_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HDV1988283.1"
                     /translation="MKKIIALMLFLTFFAHANDSEPGSQYLKAAEAGDRRAQYFLADS
                     WFSSGDLSKAEYWAQKAADSGDADACALLAQIKITNPVSLDYPQAKVLAEKAAQAGSK
                     EGEVTLAHILVNTQAGKPDYPKAISLLENASEDLENDSAVDAQMLLGLIYANGVGIKA
                     DDDKATWYFKRSSAISRTGYSEYWAGMMFLNGEEGFIEKNKQKALHWLNLSCMEGFDT
                     GCEEFEKLTNG"
     gene            complement(13467..15614)
                     /gene="fdhF"
                     /locus_tag="RHX21_003132"
     CDS             complement(13467..15614)
                     /gene="fdhF"
                     /locus_tag="RHX21_003132"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(15195..15197),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HDV1988284.1"
                     /translation="MKKVVTVCPYCASGCKINLVVDNGKIVRAEAAQGKTNQGTLCLK
                     GYYGWDFINDTQILTPRLKTPMIRRQRGGKLEPVSWDEALNYVAERLSAIKEKYGPDA
                     IQTTGSSRGTGNETNYVMQKFARAVIGTNNVDCCARVUHGPSVAGLHQSVGNGAMSNA
                     INEIDNTDLVFVFGYNPADSHPIVANHVINAKRNGAKIIVCDPRKIETARIADMHIAL
                     KNGSNIALLNAMGHVIIEENLYDKAFVASRTEGFEEYRKIVEGYTPESVEDITGVSAS
                     EIRQAARMYAQAKSAAILWGMGVTQFYQGVETVRSLTSLAMLTGNLGKPHAGVNPVRG
                     QNNVQGACDMGALPDTYPGYQYVKDPANREKFAKAWGVESLPAHTGYRISELPHRAAH
                     GEVRAAYIMGEDPLQTDAELSAVRKAFEDLELVIVQDIFMTKTASAADVILPSTSWGE
                     HEGVFTAADRGFQRFFKAVEPKWDLKTDWQIISEIATRMGYPMHYNNTQEIWDELRHL
                     CPDFYGATYEKMGELGFIQWPCRDTSDADQGTSYLFKEKFDTPNGLAQFFTCDWVAPI
                     DKLTDEYPMVLSTVREVGHYSCRSMTGNCAALAALADEPGYAQINTEDAKRLGIEDEA
                     LVWVHSRKGKIITRAQVSDRPNKGAIYMTYQWWIGACNELVTENLSPITKTPEYKYCA
                     VRVEPIADQRAAEQYVIDEYNKLKTRLREAALA"
     gene            complement(15812..17278)
                     /gene="mdtP"
                     /locus_tag="RHX21_003133"
     CDS             complement(15812..17278)
                     /gene="mdtP"
                     /locus_tag="RHX21_003133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter outer membrane
                     subunit MdtP"
                     /protein_id="HDV1988285.1"
                     /translation="MINRQLSRLLLCSILGSTTLISGCALVRKDSAPHQQLKPEQIKL
                     ADDIHLASSGWPQAQWWKQLNDPQLDALIQRTLSGSHTLAEAKLREEKAQSQADLLDA
                     GSQLQVAALGMLNRQRVSANGFLSPYAMDAPALGMDGPYYTEATVGLFAGLDLDLWGV
                     HRSAVAAAIGAHNAALAETAAVELSLTTGVAQLYYSMQASYQMLDLLEQTRDVIDYAV
                     KAHQSKVAHGLEAQVPFHGARAQILAVDKQIAAVKGQITETRESLRALIGAGASDMPE
                     IKPVALPRVQTGIPATLSYELLARRPDLQAMRWYVQASLDQVDSARALFYPSFDIKAF
                     FGLDAIHLDTLFKKTSRQFNFIPGLKLPLFDGGRLNANLEGTRAASNMMIERYNQSVL
                     NAVRDVAVNGTRLQTLNDEREMQAERVEATRFTQRAAEAAYQRGLTSRLQATEARLPV
                     LAEEMSLLMLDSRRVIQSIQLMKSLGGGYQAAPVVEKK"
     gene            complement(17275..19326)
                     /gene="mdtO"
                     /locus_tag="RHX21_003134"
     CDS             complement(17275..19326)
                     /gene="mdtO"
                     /locus_tag="RHX21_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418505.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter permease subunit
                     MdtO"
                     /protein_id="HDV1988286.1"
                     /translation="MSALNSLPLPVVRLLAFFHEELSERRPGRVPQTVQLWVGCLLVI
                     LISMTFEIPFVALSLAVLFYGIQSNAFYTKFVAILFVVATMLEIGSLFLIYKWSYGEP
                     LIRLIIAGPILMGCMFLMRTHRLGLVFFAVAIVAIYGQTFPAMLDYPEVVVRLTLWCI
                     VVGLYPTLLMTLIGVLWFPSRAISQMHQALNDRLDDAISHLTDSLAPLPETRIEREAL
                     ALQKLNVFCLADDANWRTQSAWWQSCVATVTYIYSTLNRYDPTSFADSQAIIEFRQKL
                     ASEINKLQHAVAEGQCWQSDWRISESEAMAARECNLENICQTLLQLGQMDPNTPPTPA
                     AKPPSMAADAFTNPDYMRYAVKTLLACLICYTFYSGVDWEGIHTCMLTCVIVANPNVG
                     SSYQKMVLRFGGAFCGAILALLFTLLVMPWLDNIVELLFVLAPIFLLGAWIATSSERS
                     SYIGTQMVVTFALATLENVFGPVYDLVEIRDRALGIIIGTVVSAVIYTFVWPESEART
                     LPQKLAGALGMLSKVMRIPRQQEVTALRTYLQIRIGLHAAFNACEEMCQRVALERQLD
                     SEERALLIERSQTVIRQGRDILHAWDATWNSAQALDNALQPDRAAQFADALEKYAAGL
                     ATALSRSPQITLEETPASQAILPTLLKQEQHVCQLFARLPDWTAPALTPATEQAQGAT
                     Q"
     gene            complement(19326..20357)
                     /gene="mdtN"
                     /locus_tag="RHX21_003135"
     CDS             complement(19326..20357)
                     /gene="mdtN"
                     /locus_tag="RHX21_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter periplasmic adaptor
                     subunit MdtN"
                     /protein_id="HDV1988287.1"
                     /translation="MESTPKKAPRSKFPALLVVALALVALVFVIWRVDSAPSTNDAYA
                     SADTIDVVPEVSGRIVELAVTDNQAVKQGDLLFRIDPRPYEANLAKAEASLAALDKQI
                     MLTQRSVDAQQFGADSVNATVEKARAAAKQATDTLRRTEPLLKEGFVSAEDVDRARTA
                     QRAAEADLNAVLLQAQSAASAVSGVDALVAQRAAVEADIALTKLHLEMATVRAPFDGR
                     VISLKTSVGQFASTMRPIFTLIDTRHWYVIANFRETDLKNIRSGTPATIRLMSDSGKT
                     FEGKVDSIGYGVLPDDGGLVLGGLPKVSRSINWVRVAQRFPVKIMVDKPDPEMFRIGA
                     SAVANLEPQ"
     gene            complement(20376..20651)
                     /locus_tag="RHX21_003136"
     CDS             complement(20376..20651)
                     /locus_tag="RHX21_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988288.1"
                     /translation="MPTVLSRMAMQLKKTAWIIPVFMVSGCSLSPAIPVIGAYYPSWF
                     FCAIASLILTLITRRVIQRANINLAFVGIIYTALFALYAMLFWLAFF"
BASE COUNT         4671 a         5517 c         5698 g         4878 t
ORIGIN      
        1 gaaaaggtga tgcatgctgg agaggaagag tattccccgg tcaggcgacc ggggaagggg
       61 agagattaat gtgcgcggcc ttgctcaacg ccaaagccgg tctgggagcg gataaactgt
      121 gcacggaaca gttcacgctc gcgcgcacct tccgctgagt tatcggttgc cgagaagaac
      181 cagatgccga ggaatgccac gctgatagag aacagcgccg ggtattcata cgggaagatg
      241 gctttttcgt gaccaaggat ctgtacccaa atcgtcgggc cgaggatcat cagtaccact
      301 gcggtaatca gccccagcca gccacccatc atcgcgccac gagtggtcag tttcgaccag
      361 tacatagaaa gcagaatgat cgggaagtta cagctcgctg cgatggcaaa cgccaggcct
      421 accatgaagg cgatgttctg attctcaaac agcacgccga ggataatggc aatcacacct
      481 aaaatcagca cggtgatttt cgatacccgc agttcttcac gttcggtcgc gccttttttg
      541 aagacgttag cgtacaggtc atgcgaaacc gctgatgcgc ccgccagcgt cagaccagca
      601 accaccgcaa gaatggtggc aaaagcaacc gctgaaataa aaccgaggaa caggttgccg
      661 cccactgcat tcgccaggtg aacggccgcc atgttgttac caccaatcag atggcccgcc
      721 gcgtctttat attccggatt cgcaccaacc agcatgatcg cgccgaagcc gataataaag
      781 gtcagaatat agaagtagcc cataaacccg gtggcgtaga acacgctctt acgtgcttcg
      841 cgggcatcgc tgactgtaaa gaagcgcatc agaatgtgcg gcaagcccgc cgtaccaaac
      901 atcagtccca gacccagaga gagcgcggag atcggatctt tcaccagccc gcccggcttc
      961 atgatgtcga cacctttcgg gtgtaccgcc atcgcttcac tgaacagatt gttgaagcta
     1021 aagccgacgt gtttcatcac cataaaggcc ataaagctgg caccgaacag caacagcacg
     1081 gctttgataa tctgtaccca agtggtcgcc agcatgccgc cgaacaggac gtacatcatc
     1141 atcagcacgc cgaccagcac caccgcaatg tgatagttaa ggccaaacag cagctcgatc
     1201 agtttacctg cgcccaccat ctgggcgata aggtaaagcg ccaccaccac cagagaacca
     1261 caggccgaaa gaatacgaat cggcccttgt ttcagacggt aagaggccac atcggcaaag
     1321 gtgtagcgcc ccaggttacg cagacgttcg gcaatcagga acaaaatgat cggccagccc
     1381 accaggaagc ccagcgagta aattaagccg tcatagccgg aggtaaacac cagcgcggag
     1441 atccccaaga atgaggcggc ggacatatag tccccggcaa tcgccagccc gttctggaag
     1501 ccagtgatat tgccgcctgc ggtgtagtag tcgctacgag aacgtacgcg ttttgatgcc
     1561 cagtaggtaa tgccgagcgt aaacacgacg aaaatcagga acataataat cgcctgccag
     1621 ttcgttggct ggcgctctac ggccccgcta atagcatccg cggcgttagc tgcgaaaggg
     1681 agtgtggcgg caagcgccgt cagaactctt ttcatgatgc ttgtacctca tgcaggactt
     1741 cattattaag acggtcgaat tcgccgttcg cccgccagat gtagataccg gtgagaacaa
     1801 aggagatcac aatcactcca acaccaattg gaataccgcg tgtgacgctg gtgttcggat
     1861 tcagcggcgt gcccagccag ccgggcgcga aggcgatcag taaaataaag ccgatataaa
     1921 ctgccagcat aataatcgac aggatggtgg caaaccgttg ccgtttttcg actaactccc
     1981 tgaaatgcgc attgtcttct atccgctgat aaatagtgcc attcatcaca gattctccag
     2041 aggtaatgta gggattgttt taattcccgc tcccttatgg gagaaggtta acgctcgggt
     2101 aacccttgcc gaatgtaggc cggataaggc gtttacgccg catccggcaa tcaatgcctg
     2161 atgcgacgct gtcgcgtctt atcaggccta caaaccgtta ccgactcgca tccggcaatt
     2221 gtgggttacg atggcatcgc gatagcctgc ttctcttcaa gcagcttctc gactacgcca
     2281 ggatcggcaa gcgtcgaggt atcgcccagg ttgctggtat cgcccgccgc aattttgcgc
     2341 agaatacggc gcataatttt gccggagcgg gttttaggca gggagtcggt ccagtgcagc
     2401 acgtctggcg tcgccagcgg gccaatctct ttacgcaccc agttgcggac ttctgcgtac
     2461 agttctggtg acggttcctc cccgtgatta agcgtgacgt aggcgtagat cgcctgacct
     2521 ttaatattgt gcggaatacc tactacggcg gcttcggcaa tcttcggatg cgccaccagc
     2581 gccgactcaa tctctgccgt ccccagacgg tgaccggaga cgttcagcac gtcgtccaca
     2641 cgcccggtga tccagtaata gccatcttca tcgcgacgcg cgccgtcgcc gctgaaatac
     2701 atatttttga aggtggagaa gtaggtctgt tcaaaacgtt cgtgatcgcc aaacagcgta
     2761 cgcgcctgac ccggccagga gtcggtgatc accaggctgc cttcggtagc gccttccagc
     2821 gggttacctt cgttatcgac cagcgccggt tgcacgccga agaacggacg tgttgccgaa
     2881 ccggctttca gctcggtagc gccaggcagc ggcgtgatca tgaaaccgcc agtttcggtc
     2941 tgccaccagg tatcgaccac cggacatttc tcgttgccga tttttttcca gtaccactcc
     3001 cacgcttccg ggttaattgg ctcgcccacg gaaccgagaa tgcgcagcga cgaacggtcg
     3061 gtaccctcga tcgctttatc gccttccgcc atcagcgcgc ggatcgccgt gggtgcggta
     3121 tagagaatat tgacctgatg cttgtccacc acctgcgcca tacgggcagg cgtcggccag
     3181 ttgggtacgc cttcaaacat cagcgtggtc gcaccgcagg ccagcgggcc gtacagcaag
     3241 taactgtgtc cggtcaccca gcccacatcg gcggtgcacc agtagatatc acccggatga
     3301 taatcaaaga catatttaaa ggtcagcgcc gcgtacacca gataaccgcc ggtagtatgc
     3361 agcacacctt ttggcttacc ggtagaaccg gaggtgtaga gaataaacag cggatcttcg
     3421 gcgttcatct cttccgcctg gtgctgatcg ctcgcttgct caaccaggtc gtgccaccac
     3481 aggtcgcgcc cttcctgcca gtcaattttc ccgccagtac gcttcagtac caccacatgc
     3541 tctacgctgg tgacgttcgg gtttttcagc gcgtcatcaa cgtttttctt cagcggaata
     3601 ctgcgcccgg cacgcacacc ttcgtcggaa gtgatcacca gtcgtgagtt ggaatcaata
     3661 atgcgcccgg caacggcttc cggcgagaag ccgccgaaaa tcaccgaatg caccgcgcca
     3721 atgcgggcgc aggccagcat cgcaaccgcg gcttccggca ccatcggcat ataaatcgcc
     3781 accacatcac cttttttaat gcccagctcg agcagggtat tggcgaagcg gcagacgtcg
     3841 cggtgcagct ctttatagct gatatgtttg ctctggctgg cgtcgtcgcc ttcccagatg
     3901 atggcggtgc gatcgccgtt ttcttgcaga tggcggtcaa ggcagtttgc cgccagattc
     3961 agcgtgccgt cctcgtacca tttaatggac acattaccgg gggcaaagga ggtatttttc
     4021 accttctggt aaggtttgat ccagtcgaga atttttccct gttcgcccca gaaggtatca
     4081 ggtacgttaa tagattgttg atacatcgcc tcgtactgct gagggtttat caggcaacgg
     4141 tctgcgatgt tggcaggaat ggtgtgtttg tgaatttggc tcatgctttt gttctccttg
     4201 taggatgtta ataatatgtg gcataagcgt taaatgtagg ggtattggca gttttgttta
     4261 gtatttgggc gacagatcac gcaaaagtag aattgtgcaa ataaacggca gggtaatttt
     4321 tgaaggtcag caacaaaagt tgattaattc tttgaggaac atgcagttat gcatgctgtt
     4381 gaaaaagagg aagatactga ctaactctaa agtggtattt tacatgcact tacaattgat
     4441 taaagacaac attcacagtg tggttatttg ttacacatag gggcgagcaa tgtcatgaca
     4501 gtgtaggtgc ggttactgtc gtgaaaacaa taaaaaccgc cattgcaaca atggcgcaat
     4561 tcggatgaag cccctatgac aaggataaaa ataaacgcac gccgtatctt cagcttattg
     4621 attccttttt tctttttcac ttctgttcac gctgaacaaa cggcagctcc cgcaaaacct
     4681 gtaactgtgg aagcgaagaa tgaaaccttt gccccgcagc atcccgatca atatctctcc
     4741 tggaaagcca cctcggaaca gtcagagcgt gttgacgccc tggcggaaga tccacggctg
     4801 gtgatcctgt gggcggggta tcccttctcg cgcgattaca acaagccgcg tggacatgcc
     4861 tttgctgtga ccgatgtgcg tgaaaccctg cgtaccggtg cgccgaaaaa cgctgaagat
     4921 ggtccgctac cgatggcgtg ctggagttgt aaaagcccgg atgtggcgcg tctgatccag
     4981 aaagacggcg aagatggcta cttccacggt aagtgggcgc gcggcggccc ggaaatcgtc
     5041 aacaacttag gttgtgccga ctgccataac accgcctcac cagagttcgc caaaggcaaa
     5101 ccggagttaa ccctttcccg tccgtatgcg gctcgcgcga tggaagccat tggtaaacct
     5161 tttgagaaag ccggacgttt cgaccagcaa tcgatggttt gcggtcagtg ccatgtggag
     5221 tattacttcg acggcaaaaa caaagcggtt aaattcccgt gggatgacgg catgaaagtc
     5281 gaaaatatgg agcagtatta cgacaaaatt gccttctctg actggactaa ctccctgtcg
     5341 aaaacgccaa tgctgaaagc gcagcacccg gaatatgaaa cctggacagc gggcattcac
     5401 ggtaaaaaca acgtgacctg tatcgactgc catatgccaa aagtgcagaa cgccgaaggc
     5461 aaactctaca ccgaccataa aattggtaat ccgtttgata acttcgccca gacttgtgcg
     5521 aactgccata cccaggacaa agctgccttg caaaaagtgg tcgcggaacg taagcagtcg
     5581 attaacgacc tgaaaatcaa ggttgaagat caactggttc acgctcactt cgaagcgaaa
     5641 gcagcgctgg atgcaggcgc gacggaagcc gaaatgaagc caattcagga cgatatccgt
     5701 catgcccagt ggcgctggga tctggcgatc gcttcccacg gcattcatat gcacgcaccg
     5761 gaagaaggtt tacggatgct cggtacggcg atggataaag cggcggatgc acgcaccaaa
     5821 ctggcgcgcc tgctggcgac caaaggcatc acccatgaaa tccagatccc ggatatctca
     5881 accaaagaga aagcccagca ggctattggc ctgaacatgg aacaaatcaa ggccgagaag
     5941 caggacttca tcaaaacggt gatcccgcag tgggaagaac aggcacgtaa aaacggtctg
     6001 ttaagccaat aaccccgttc cgcctcgcaa ggggcggaaa acacaatgga gtgaatatga
     6061 gcgtattacg ttcgttatta actgccgggg tgctggcgtc gggcctgttg tggagcctga
     6121 acggaattac cgctacccct gcggcgcagg catctgatga tcgctacgaa gttacccagc
     6181 agcgtaaccc ggatgccgcc tgtctggact gtcataagcc agataccgaa ggtatgcatg
     6241 gaaaacatgc ttccgttatc aacccgaata acaaactgcc ggtcacctgc accaactgtc
     6301 acggccagcc atcaccgcaa caccgcgaag gggtgaaaga tgtgatgcgc tttaacgagc
     6361 cgatgtacaa ggttggagag cagaacagcg tctgtatgtc ctgtcatctg ccggaacagt
     6421 tgcaaaaagc gttctggccg cacgatgtcc acgtaaccaa agtggcgtgc gccagctgcc
     6481 attccctgca tccacagcaa gatacgatgc agacgttaag tgacaaagga cggattaaga
     6541 tttgcgtcga ttgccacagc gatcagcgca ccaatccgaa ctttaacccg gcgtctgttc
     6601 cgttgcttaa ggagcagcca tgacctggtc tcgtcgccag tttctcaccg gcgtcggcgt
     6661 gctggcagcc gtcagcggca ccgcagggcg cgtggtggcg aaaacgttga atatcaatgg
     6721 ggtgcgttac ggcatggtgc atgacgagtc gttatgcatc ggctgtaccg cctgtatgga
     6781 tgcttgtcgg gaagtgaaca aggtgccgga aggcgtctcg cgcctgacga ttattcgtag
     6841 cgagccgcag ggcgaatttc ctgatgtgaa atatcgcttc ttccgtaagt cttgccagca
     6901 ctgcgatcat gcgccgtgcg ttgacgtctg cccgaccggt gcgtcttttc gtgatgccgc
     6961 tagcgggatt gtcgatgtta atcctgatct ctgcgtcggt tgtcagtact gcatcgccgc
     7021 ctgtccgtac cgcgtgcgct ttatccatcc ggtcacgaag acggcggaca aatgcgattt
     7081 ctgccgtaaa accaatttgc aggccggtaa gctgcccgcg tgcgttgagg cttgcccgac
     7141 gaaggcgctg acgtttggca atctggacga tcctaacagt gagatttcgc aactgctgcg
     7201 ccagaagcct acttaccgct acaagctggc gctgggaacc aaaccgaagc tgtaccgcgt
     7261 accgtttaaa tacggggagg tgagccaatg acgcagactt ccgcatttca ttttgaatcg
     7321 ctggtgtggg actggccgat tgccatctac ctgtttttga ttggtatttc tgccggtctg
     7381 gtgacgctgg ccgtgctgtt acgtcgcttc tacccgcagg cgggcggtgc agacagtacg
     7441 ttgctgcgca ccacgctgat tgtcgggccg ggcgcggtga tcctcggtct gttgatcctc
     7501 gtcttccacc tgacaagacc gtggaccttc tggaagctga tgttccacta cagttttacc
     7561 tcggtgatgt cgatgggggt gatgctgttt cagctctaca tggtggtgct ggtgctgtgg
     7621 ctggcgaaaa tctttgaaca tgatttgctt gccctgcaac aacgctggtt gccgaagctg
     7681 gggatcgtgc aaaaggttct gagcctgctg acgcccgttc atcgcggact ggaaacattg
     7741 atgctggtgt tggcggtgtt gttgggggct tataccggct ttctgctgtc ggcgctgaaa
     7801 tcgtatccgt tcctcaataa cccgatcctg ccggtgctgt tcctcttctc cggcatctcg
     7861 tccggtgcgg cggtggcgct gatcgccatg gcgatacgcc aacgcagtaa cccgcattcc
     7921 acggaagcgc agtttgtaca ccgtatggaa atccccgtgg tatggggtga aatcttcctg
     7981 ctggtggcgt tttttgtcgg tctggcgctg ggcgatgacg gtaaagtgcg tgcgctggtg
     8041 gcggcattag gtggcggttt ctggacgtgg tggttctggc ttggtgtcgc cgggctgggg
     8101 ctgattgtgc caatgttgct caaaccgtgg gtcaatcgca gttccggcat tcctgccgtg
     8161 ctggcggcgt gtggggccag tctggtcggc gtgttgatgc tgcgcttttt cattctctac
     8221 gccgggcagt taacggtggc gtaagccaga aaagaggtgg tttctggacg tattccttcc
     8281 tgaagtcggt tttctggcgt tgttgttaag tctcggggtc aacgtgttga ccccgttgac
     8341 ggcctttgcg ggagtgcggt tgcgctggcc tgccatgatg cgactcactt gcatcggcat
     8401 tctggcgcag ttcgcgctcc tgttgctcgc ctttggcgta ctgacgtatt gttttctcat
     8461 cagcgatttc tcggtcattt atgtcgccca acatagctac agcctgctgt cgtgggaact
     8521 caagctggca gcggtgtggg gcggccatga aggttcgctg ctgctttggg tgctgctgct
     8581 ttccgcctgg agcgcgctgt ttgcctggca ttatcggcag caaaccgatc cgctatttcc
     8641 gctgacgcta gccgttttat ctctcatgct cgccgcactg ctactgtttg tagtgctgtg
     8701 gtccgatccc ttcgtgcgga tatttccacc agcaatcgaa ggccgcgatc tcaatccgat
     8761 gctgcaacat cccggtctta tctttcatcc accgctgctt taccttggct atggcggttt
     8821 gatggtggcg gcgagcgtgg cgctggcgag tttactgcgc ggcgagtttg atggtgcctg
     8881 cgccagaatt tgttggcgct gggcactacc tggctggagc gcattaacgg cggggatcat
     8941 cctcggttcc tggtgggcct attgcgaact gggctggggc ggctggtggt tctgggatcc
     9001 ggtggaaaac gcctctttat taccctggct ttctgccact gcgctgctgc acagtttgtc
     9061 cctgacacgc cagcgggaga ttttccgcca ctggtcgctg ttgctggcga tagtaactct
     9121 gatgctgtcg ctactgggta ccttaattgt ccgttctggc attctggttt cggttcatgc
     9181 gttcgcactg gataacgtcc gcgccgtgcc gttgttcagc ctgtttgcac tgattagcct
     9241 tgcgtctctg gctctgtatg gctggcgagc gcgggacggt ggcccggtgg tgcgtttttc
     9301 ggggttatcg cgggaaatgt taatcctcgc tacgctgttg ctgttttgcg cagtgctact
     9361 gatcgtgctg gtgggaacgc tttatccgat gatttacggt ctgctgggct ggggacgcct
     9421 ctccgttggc gcgccgtatt ttaaccgcgc gacgttaccg tttggcctgt tgatgctggt
     9481 ggtgattgtg ctggcgacgt ttgtctctgg caaacgcgtg cagcttccgg cgctggtagc
     9541 tcatgcgggc gtgctgttat ttgccgctgg gatcgtggtt tccagcgtca gccgtcagga
     9601 gatcagcctg aatttacagc cgggtcagca ggtgacgctg gcaggataca ccttccgttt
     9661 tgagcgcctc gatctgcaag ccaaaggcaa ttacaccagc gaaaaagcga tagtggcact
     9721 gtttgaccat cagcaacgca ttggtgaact gatgccggag cggcgttttt acgaagcacg
     9781 tcgtcagcaa atgatggaac cgtcaattcg ctggaacggc atccatgact ggtatgcggt
     9841 catgggtgaa aaaaccggag cggatcgtta cgcttttcgc ttgtatgtac aaagcggtgt
     9901 gcgctggatc tgggggggag gattgttgat gattgcgggc gcattgttaa gcggatggcg
     9961 ggggaggaag cgcgatgaat aaaggacttc tcacgctact gctgttattt acctgttttg
    10021 cgcgcgctca ggtcgtagac acctggcaat ttgccaatcc gcaacaacag caacaggcgt
    10081 taaatattgc cagccagtta cgttgtccgc agtgccagaa tcaaaactta ctggaatcca
    10141 acgcgccggt ggcagtcagt atgcgccatc aggtttacag catggtggcg gaggggaaga
    10201 acgaagtcga aatcattggc tggatgaccg aacgctacgg agattttgtt cgctataacc
    10261 caccgttaac gggtcagacg ctggtgttgt gggcgctgcc agtggtgttg ttactgctga
    10321 tggcactgat cctctggcga gtgagggcga agcgatgaaa gagcccaaaa taccggtgaa
    10381 aatgctgaca acactcacga ttttgatggt atttctctgt gtcggcagtt atctgttaag
    10441 tccaaaatgg caggcggtac atgcggaata tcagcgtcag cgcgatccgc tacatcagtt
    10501 tgccagccag caaaccccgg aagcgcagct tcaggcattg caggataaaa tccgcgctaa
    10561 tccacaaaac agcgaacaat gggcgttact gggcgagtac tatctgtggc aaaacgatta
    10621 cagcaattcg ctgctggcgt accgtcaggc gttgcaacta cgtggtgaga acgctgaact
    10681 gtatgcggcg ctggcgacgg tgctttatta ccaagccagc cagcatatga ccgcccagac
    10741 tcgcgcaatg atcgacaaag ccctcgcgct ggactctaac gaaatcaccg ctctgatgct
    10801 gctggcttcc gatgcgttta tgcaggcgaa ttacgcgcaa gccatcgaac tatggcaaaa
    10861 agtgatggat ctcaactcac cccggatcaa ccggacacag ctggtcgagt cgattaatat
    10921 ggcgaaattg ttgcagcgga gatcagatta atcatctggt gatgaagatt atgttattga
    10981 gttgtataaa aaataatcga atgaacatat gccaaaaata atcaccaatc agtattattg
    11041 cagattaaac aaataaaaat ctttccataa caaatggtta ttcattaatc ctgccataaa
    11101 ctcgcgttat tatgcattaa tgcagcgaaa agctctgttg ttaaagggtt gcgcaacata
    11161 ccgcgcaaat gatactgatc ataagcgtta aaaaaatcta caaaccaacg caacacaatt
    11221 catgccctgg cagtatgtca cgttctcgcg tttctgaacg gggaacggcg ctccattgag
    11281 gaagttattc tgatgaaaag tataaaattc agcctggcct ggcagattct gtttgctatg
    11341 gtgctgggca ttctcctggg aagctacctg cactaccata gcgacagccg cgactggctg
    11401 gtcgtcaatt tgctctctcc ggcgggtgat atcttcatcc atctgatcaa aatgattgtt
    11461 gtgccgattg tgatctccac gctggtggtg ggtatcgcgg gtgttggtga tgccaaacag
    11521 ctcgggcgta ttggcgcgaa aaccattatt tacttcgagg tgatcaccac cgtcgccatc
    11581 attttgggga tcactctggc gaacgtcttc cagcccggtg ccggggtgga tatgtcgcag
    11641 ttggcgaccg tcgatatctc gaaatatcag agcactacgg aagcggtaca aagcagttcc
    11701 cacggcatta tgggcacgat tttgtcgctg gtgccgacga acattgtggc gtcgatggcg
    11761 aaaggcgaaa tgctgccgat catcttcttc tcggtgctgt ttggtctggg gctttcctcc
    11821 ctgcccgcga cgcatcgtga accgctggtg accgtgttcc gctccatctc tgaaaccatg
    11881 tttaaagtga ctcacatggt gatgcgttat gcaccggtgg gtgtgtttgc gctgattgcg
    11941 gtgacggtgg ctaactttgg tttctcttct ctgtggccac tggcgaaact ggtgctgctg
    12001 gtgcatttcg ccattctgtt cttcgcgctg gtagtgctgg gaattgtggc gcgcctgtgc
    12061 gggttaagcg tctggatcct gattcgtatt ctgaaagatg agctgattct ggcgtactcc
    12121 actgccagct ctgaaagcgt actgccgcga attattgaga agatggaagc ctacggagca
    12181 ccggcgtcga tcaccagctt cgtggtgccg accggttact cttttaacct tgatggttcg
    12241 acgctgtatc aaagtattgc cgctattttc atcgctcagc tgtatggcat tgacctgtcc
    12301 atctggcagg aaatcattct ggtgctgacg ctgatggtga cctcgaaagg gattgctggc
    12361 gtgccgggcg tgtcgtttgt ggtgctgctg gcaacgctgg gtagcgtagg tattccgctg
    12421 gaaggcctgg cgtttattgc tggtgttgac cgtatcctcg acatggcgcg tactgcgctg
    12481 aacgtggtgg gtaatgcgct ggcggtgctg gtgattgcca agtgggaaca caaatttgac
    12541 cgcaaaaagg cgctggctta tgagcgtgaa gtgctgggca aatttgataa aactgcggat
    12601 caataattga agattgccgg ggttatccac ccggcaatgt gtggatgcct gatgcgacgc
    12661 tggtgcgtct tatcaggcct accttaaccg ttggttaatt tttcaaactc ttcacacccg
    12721 gtatcaaacc cttccataca gctcaggttc aaccagtgca gcgccttttg tttgttcttc
    12781 tcgataaaac cttcctcacc gtttaagaac atcattcccg cccagtactc ggaataaccg
    12841 gttcgggaaa ttgcagagct gcgtttgaaa taccaggttg ccttgtcatc gtcggcctta
    12901 atgcccacgc cgttggcgta aatcaaacca agcagcattt gggcatcgac ggcggagtca
    12961 ttctccagat cttccgaggc gttttctaac agcgaaatcg cctttggata atccggttta
    13021 cccgcttgag tatttaccag aatatgcgcc agcgttactt caccttcttt actgcccgct
    13081 tgcgccgctt tctctgcaag aacttttgct tgtggatagt ccagactgac cggattggtg
    13141 attttgatct gcgccagcag cgcgcaggca tcagcatcac cgctgtcggc ggctttctgt
    13201 gcccaatatt cggctttgct caaatcgccg gagctaaacc agctgtcggc aagaaaatat
    13261 tgtgcgcgtc ggtccccggc ctctgctgcc tttaaatact ggctgccagg ctcggagtcg
    13321 ttcgcgtggg caaagaatgt caaaaacaac atcaatgcga taattttttt cattttgata
    13381 atacgattgg gtagggagta accagtataa agagttcgaa tggataaaaa aacagcctcc
    13441 gaaaggaggc tgtagaaagg actgtattac gccagtgccg cttcgcgcag gcgagttttc
    13501 aacttgttgt actcgtcaat cacgtactgc tcggcggcgc gctgatcggc gatcggctcg
    13561 acgcgcacgg cgcagtattt gtattccggc gttttcgtaa tcgggcttaa gttttcggta
    13621 accagctcgt tacaggcacc aatccaccac tggtaggtca tgtaaatcgc ccctttgttc
    13681 ggacgatcgc tgacctgcgc acgggtgata attttgcctt tacgcgagtg cacccaaacc
    13741 aatgcctcat cttcaatacc cagacgtttg gcgtcttcgg tattgatttg tgcgtagcca
    13801 ggttcatcag ccagcgccgc cagtgccgca cagttaccgg tcatcgaacg gcaagagtag
    13861 tgaccaactt cacgcaccgt tgacagtacc atcgggtact cgtcggtgag tttgtcgatt
    13921 ggcgctaccc agtcgcaggt gaagaactgt gccagaccgt tcggggtatc aaacttctct
    13981 ttaaacagat aagaagtccc ctgatcggca tctgaagtat cgcggcaagg ccactgaatg
    14041 aagcccagtt cgcccatttt ctcgtaagtc gcaccgtaga aatccgggca cagatgacgc
    14101 aactcatccc agatctcctg ggtgttgttg tagtgcatcg gataacccat acgggtggcg
    14161 atttcactga tgatttgcca gtccgttttc agatcccatt tcggttcaac tgctttgaag
    14221 aaacgctgga agccacggtc agccgcagta aacacgcctt catgctcgcc ccacgacgtt
    14281 gacggcaaaa tgacatccgc cgccgacgcg gttttggtca taaagatgtc ctgaacgata
    14341 accagttcca gatcttcaaa ggctttacgt actgccgaca gctccgcgtc agtttgcagc
    14401 ggatcttcgc ccataatgta cgcggcacgc acttcgccat gcgctgcgcg gtgcggcagc
    14461 tcgctgatgc gataaccggt atgagcaggc aggctttcca cgccccaggc tttggcgaat
    14521 ttctcgcggt tagccggatc tttcacgtac tggtatcccg gatacgtatc cggcagcgcg
    14581 cccatatcgc aggcaccctg cacgttgttc tgaccacgaa ccgggtttac acccgcatgc
    14641 ggcttaccga ggttaccggt cagcatcgcg aggctggtca gagaacgcac ggtttccacg
    14701 ccctggtaga actgggttac acccatgccc cacaggatgg cggcgctttt cgcctgggca
    14761 tacatccgtg ccgcctgacg aatctcactg gcgctgacgc cggtgatatc ttcaaccgac
    14821 tccggcgtgt agccttcaac gattttacga tactcttcaa agccttctgt acgggaagcg
    14881 acgaacgctt tgtcgtacag attttcttca ataatgacat ggcccatcgc attcaacagc
    14941 gcgatgttcg agccgttttt cagtgcaatg tgcatgtcag caatgcgcgc ggtttcaatt
    15001 ttgcgcggat cgcagacgat aattttcgcc ccgttacgtt tagcgttaat tacgtgattc
    15061 gccacgattg ggtgggaatc cgccgggttg tacccgaaaa cgaacactaa atcggtatta
    15121 tcaatttcgt taatagcatt gctcattgcg ccattaccga ccgattggtg cagacctgca
    15181 accgatgggc cgtgtcagac acgagcgcag cagtcaacgt tattggtacc aataacggcg
    15241 cgcgcaaatt tttgcattac atagttggtt tcgttacccg taccacgcga ggagccggtc
    15301 gtctggatgg catccggacc gtacttctct ttgatggcgc tcaggcgctc ggcaacgtaa
    15361 ttcagtgcct catcccagga aacaggttcg agtttgccgc cacgctggcg acggatcatg
    15421 ggggttttca ggcgcggggt caggatctgg gtatcgttaa tgaaatccca gccataataa
    15481 cccttcagac acagggtacc ctggttggtt ttcccctgcg ctgcctccgc ccggacgatt
    15541 ttgccgttat cgacgaccag gttgattttg caacctgatg cgcaataggg gcaaaccgtg
    15601 acgacttttt tcatcggtct cgctccagtt aatcaaatca cgcatacgcg ctctcgacta
    15661 cagtatgcat cttttatgcc acattttatt tggggtcatt ccctgatatt acgggcacta
    15721 tttattcaaa actctgacga aaaacaggct gtcgtcagtt ttgacgtgac gaaacgaaat
    15781 accgcgtgac agccatcacg cggcagacat tttatttttt ctcgacgacg ggagccgcct
    15841 gatacccgcc gcccagcgat ttcatcaact gaatgctttg gatcacccgg cggctgtcca
    15901 gcatcagtaa tgacatctct tcggcaagta ctggcaaccg ggcttcagtg gcctgtaagc
    15961 ggctggttaa gccgcgctga taggcggcct cggcagcgcg ctgggtgaag cgcgttgctt
    16021 ccacgcgttc agcctgcatt tctcgctcgt cgttgagcgt ttgcagacgc gtgccgttga
    16081 cggcaacgtc acgcaccgcg ttcagtactg actggttgta acgttcaatc atcatgttgc
    16141 tggcggcgcg cgtgccttcg agattggcat tcaaccgtcc accgtcaaac agcggcaatt
    16201 tcagacccgg gatgaagttg aactggcgac tggttttttt gaataaggta tccaggtgga
    16261 tggcatcaag gccgaaaaac gctttgatat caaagctcgg gtagaacagc gcccgcgcgg
    16321 aatccacctg atctaatgac gcctgaacat accagcgcat ggcttgcaga tccgggcgtc
    16381 tggcgagcaa ctcataagag agtgtcgccg gaatgccggt ctggactcgt ggtaatgcca
    16441 ccggtttgat ctccggcata tcgctggccc ccgcgccaat caatgcacgc agagattctc
    16501 gcgtttcggt gatttgccct ttgacggcag caatttgttt atcgaccgcc agaatctgtg
    16561 cccgcgcgcc gtggaaaggc acttgtgctt ccagaccgtg cgccacttta ctctggtgcg
    16621 ctttcaccgc gtaatcaatc acatcgcgag tttgttctaa cagatcgagc atctgatagc
    16681 tggcctgcat actgtaataa agctgcgcta cgcccgtggt cagcgatagc tctactgctg
    16741 cggtttctgc cagcgcggca ttatgcgcgc caatggcggc ggcaaccgct gagcgatgca
    16801 caccccacaa atcaagatcc agtccggcaa acaaacctac tgtggcttcc gtatagtacg
    16861 gcccgtccat acccagtgcg ggcgcatcca tcgcataagg gcttaaaaag ccgttcgccg
    16921 agacgcgttg gcggttgagc atccctaacg ctgcgacctg taattgtgaa ccggcatcta
    16981 acaaatcggc ctgggactgc gctttttctt cccgcagttt cgcttcggcg agggtgtgtg
    17041 aaccacttag cgtccgttgg atcagcgcat ccagctgcgg gtcattgagt tgtttccacc
    17101 actgcgcctg cggccagccg gagctggcaa gatgaatatc gtcggccagt ttgatttgtt
    17161 ccggtttgag ctgttgatga ggtgcagaat ccttacgtac cagggcacag ccggaaatca
    17221 gcgtcgtgct gccgagaatg ctgcacaaca gcagacgtga aagttgacga ttgatcattg
    17281 cgtggctcct tgtgcctgtt ccgtggcggg cgttaatgcc ggggctgtcc agtctggcaa
    17341 gcgggcgaaa agctggcaga cgtgttgctc ctgttttaat aaggtgggca ggatggcctg
    17401 cgaggcgggt gtctcttcaa gcgttatttg aggagaacgg ctgagtgcgg ttgccagacc
    17461 ggcagcgtat ttctccaggg cgtcggcaaa ctgagctgct ctgtccggct gtagtgcgtt
    17521 atccagcgcc tgcgccgagt tccaggtggc atcccaggcg tgaagaatat cgcggccctg
    17581 acgaataacc gtttgcgaac gttcaatcag taaggcgcgt tcttcgctgt ccagttgacg
    17641 ctccagcgcc acgcgttggc acatctcttc acaggcatta aacgccgcat gcagaccgat
    17701 acgaatttgc agataagtgc gcagagccgt gacttcctgc tgccgtggga tccgcattac
    17761 tttacttaac atacccagcg cgccagccag tttttgcggc agcgtgcgcg cttcactttc
    17821 aggccagaca aaggtgtaaa tcaccgcgga caccacggta ccaatgatga tacccagggc
    17881 gcgatcgcga atttccacca ggtcgtacac tgggccaaaa acgttttcga gcgtggcgag
    17941 cgcgaaggtg accaccatct gtgtgccgat ataagaagag cgttcagagc tggtggcaat
    18001 ccatgcgccc aacaggaaaa tcggggccag cacaaacagc aattcgacaa tattgtccag
    18061 ccagggcatg accagtagcg tgaataacag cgccagaatc gcgccgcaaa aggccccgcc
    18121 aaaacgcagc accatcttct ggtacgacga accgacattt gggttagcga cgatcacgca
    18181 tgtcagcata caggtgtgaa tgccttccca gtccacgccg ctgtaaaagg tgtaacagat
    18241 caaacaggcg agcagcgttt ttaccgcgta gcgcatatag tctggattgg taaaagcatc
    18301 ggcggccatt gatggcggtt tggctgcggg cgttggcggc gtattcgggt ccatctgacc
    18361 cagttgtaac aacgtctggc agatattctc caggttacat tcccgtgccg ccatcgcttc
    18421 actttcactg atccgccagt cgctttgcca gcactgacct tcagcaacgg catgctgcag
    18481 cttgttgatt tctgaagcta atttttgtcg gaattcaata attgcctgag aatcagcaaa
    18541 agaggtggga tcgtagcgat tcagcgtcga gtaaatgtag gttaccgttg ccacgcagct
    18601 ttgccaccat gcgctttgag ttcgccagtt ggcatcgtcc gcgagacaaa agacattcag
    18661 tttttgcagc gccagcgcct ctctttcaat ccgcgtttcg ggtagcggtg cgaggctgtc
    18721 cgtcaggtgg ctaatggcat catcaagccg atcattaagc gcctgatgca tttgcgaaat
    18781 ggcacgactg ggaaaccaca gcacgccgat taacgtcatc agcaaggttg gatagaggcc
    18841 aacaacgata caccacagcg ttaagcgcac gaccacttcc ggatagtcga gcatggcggg
    18901 gaaggtttgc ccgtaaatgg cgacaatggc gactgcgaaa aagaccagtc ccagccgatg
    18961 ggtgcgcatc aaaaacatac agcccatcag gatcggcccg gcgatgatca atcggatcaa
    19021 cggttcgccg tatgaccatt tgtagatcaa aaacaggctg ccgatctcca gcatcgtggc
    19081 gaccacaaat aagatcgcga caaatttggt gtaaaacgcg ttcgactgaa taccgtaaaa
    19141 cagcactgcc agcgataacg ccacgaaagg gatctcaaag gtcatcgaga tcagaatcac
    19201 cagcaggcag cctacccaga gttgcacggt ctgcggcacg cggcctggtc gccgctcgct
    19261 taactcttca tgaaagaacg ccagcagcct gaccaccggt aatggcaggg agttgagcgc
    19321 gctcattatt gcggctcaag attagcgact gccgaagcgc cgatgcggaa catttccggg
    19381 tcaggtttat cgaccatgat tttgaccgga aaacgctggg caacgcggac ccagttaata
    19441 gagcgagaaa ctttcggcag gccgcccagc accaggccgc cgtcatccgg tagcacgccg
    19501 tagccaatcg aatccacttt accctcgaag gttttgccgc tgtcactcat caggcgaatc
    19561 gttgcgggtg tacctgagcg aatatttttc agatcggttt cgcggaagtt ggcgatcacg
    19621 taccagtgac gagtgtcgat tagggtaaaa atagggcgca tcgtagatgc aaactgcccg
    19681 acggaggttt tgagggaaat gacccggcca tcaaacggcg cgcgaacggt cgccatttcc
    19741 agatgcagtt tggtcagggc aatatccgct tcgaccgccg cacgctgggc aactaatgca
    19801 tccacgccgc tgacggcgct ggcggctgac tgcgcctgca acaatacagc attaagatcg
    19861 gcttctgcag cgcgctgcgc ggtcctcgca cggtcaacgt cttccgctga gacaaaacct
    19921 tctttcagta atggctcggt gcggcgtaat gtatctgtgg cctgtttcgc ggcggcacgg
    19981 gctttttcta ccgtggcgtt aaccgagtcg gcaccaaact gttgcgcgtc aacgctacgc
    20041 tgggtgagca taatttgctt atccagcgcc gcgagggagg cttcagcttt cgccagattg
    20101 gcttcgtacg ggcgcgggtc aatgcggaac agcaaatcgc cctgtttgac tgcctggttg
    20161 tcggtgaccg ccagttctac aatgcgaccg ctgacttccg gcaccacatc aatggtatct
    20221 gctgacgcgt aagcgtcatt agttgatggc gcactgtcta cgcgccagat aacgaaaaca
    20281 agggcaacca gcgccaacgc aaccactaac agagcaggga atttactgcg aggagctttt
    20341 ttcggcgtac tttccatgag cgcgtctcaa atagattaga aaaatgccag ccagaacagc
    20401 atggcgtaga gagcaaaaag ggcggtataa ataattccga caaatgccag attgatattt
    20461 gcccgctgaa taactcgcct cgtgatgagc gtcaaaataa ggctggcaat ggcgcagaaa
    20521 aaccagctgg gataataagc gccgatcacc gggattgccg gagataatga gcatcccgaa
    20581 accatgaaga cgggaattat ccaggctgtt tttttgagtt gcatcgccat gcgagagaga
    20641 actgttggca tattaaatac atcctgtctg ctgcgaacaa tatctgtagt gaatatcaac
    20701 atccattgaa ggcgtcagta tggctatttt cttgatgaat aaaaatagct ttattcagcc
    20761 accg
//
LOCUS       DAPGUL010000081        20087 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.082, whole genome shotgun sequence.
ACCESSION   DAPGUL010000081 DAPGUL010000000
VERSION     DAPGUL010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20087
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.082"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(148..894)
                     /gene="cutC"
                     /locus_tag="RHX21_003137"
     CDS             complement(148..894)
                     /gene="cutC"
                     /locus_tag="RHX21_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310611.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HDV1988289.1"
                     /translation="MALLEICCYSMECALTAQQNGADRVELCAAPKEGGLTPSLGVLK
                     SVRQRVTIPVHPIIRPRGGDFCYSDGEFAAILEDVRTVRELGFPGLVTGVLDVDGNVD
                     MPRMEKIMAAAGPLAVTFHRAFDMCANPLNTLNNLAELGIARVLTSGQKSDALQGLSK
                     IMELIAHRDAPIIMAGAGVRAENLHHFLDAGVLEVHSSAGAWQASPMRYRNQGLSMSS
                     DAHADEYSRYVVDGAAVAEMKGIIERHQAK"
     gene            complement(908..1474)
                     /locus_tag="RHX21_003138"
     CDS             complement(908..1474)
                     /locus_tag="RHX21_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310612.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDV1988290.1"
                     /translation="MANWQSIDELQDIASDLPRFTHALDELSRRLGLNITPLTADHIS
                     LRCHQNATAERWRRGFEQCGELLSENMINGRPICLFKLHEPVQVAHWQFSIVELPWPG
                     EKRYPHEGWEHIEIVLPGDPETLNARALALLSDEGLSLPGISVKTSSPKGEHERLPNP
                     TLAVTDGKTTIKFHPWSIEEIVASEQSA"
     gene            1690..3423
                     /gene="argS"
                     /locus_tag="RHX21_003139"
     CDS             1690..3423
                     /gene="argS"
                     /locus_tag="RHX21_003139"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HDV1988291.1"
                     /translation="MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGM
                     MAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGPGFINIFLDPAFLAEHVQQALAS
                     DRLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVG
                     DWGTQFGMLIAWLEKQQQENAGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQ
                     SGDEYFREMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKG
                     LAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVL
                     YYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLAD
                     LLDEALERARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNML
                     AFEGNTAPYMQYAYTRVLSVFRKAEIDEEQLAAAPVIIREDREAQLAARLLQFEETLT
                     VVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAKTLKLGL
                     DTLGIETVERM"
     gene            3600..4088
                     /locus_tag="RHX21_003140"
     CDS             3600..4088
                     /locus_tag="RHX21_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme inhibitor LprI family protein"
                     /protein_id="HDV1988292.1"
                     /translation="MFKFLVLTLGIISCQVYAEDTLIVNDHDISAIKDCWQKNSDDDS
                     DINVIKSCLRQEYNLVDAQLNKAYGEAYRYIEQVPRTGVKKPDTEQLNLLKKSQRAWL
                     DFRDKECELILSNEDVQDLSDPYSESEWLSCMIIQTNTRTRQLQLYRNSEDFYPSPLT
                     RG"
     gene            complement(4208..4600)
                     /gene="flhe"
                     /locus_tag="RHX21_003141"
     CDS             complement(4208..4600)
                     /gene="flhe"
                     /locus_tag="RHX21_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlhE"
                     /protein_id="HDV1988293.1"
                     /translation="MRTLLAILLFPLLVQAAGEGMWQASSVGITLNHRGESMSSAPLS
                     TRQPASGLMTLVAWRYQLIGPTPSGLRVRLCSQSRCVELEGQSGTTVAFSGIAAAEPL
                     RFIWEVPGGGRLIPPLKVQRNEVIVNYR"
     gene            complement(4600..6678)
                     /gene="flhA"
                     /locus_tag="RHX21_003142"
     CDS             complement(4600..6678)
                     /gene="flhA"
                     /locus_tag="RHX21_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HDV1988294.1"
                     /translation="MSNLAAMLRLPANLKSTQWQILAGPILILLILSMMVLPLPAFIL
                     DLLFTFNIALSIMVLLVAMFTQRTLEFAAFPTILLFTTLLRLALNVASTRIILMEGHT
                     GAAAAGKVVEAFGHFLVGGNFAIGIVVFVILVIINFMVITKGAGRIAEVGARFVLDGM
                     PGKQMAIDADLNAGLIGEDEAKKRRSEVTQEADFYGSMDGASKFVRGDAIAGILIMVI
                     NIVGGLLVGVLQHGMSMGHAAESYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQD
                     VGEQMVNQLFSNPSVMLLSAAVLGLLGLVPGMPNLVFLLFTAGLLGLAWWIRGREQKA
                     PAEPKPVKMAENNTVVEATWNDVQLEDSLGMEVGYRLIPMVDFQQDGELLGRIRSIRK
                     KFAQEMGFLPPVVHIRDNMDLQPARYRILMKGVEIGSGDAYPGRWLAINPGTAAGTLP
                     GEATVDPAFGLNAIWIESALKEQAQIQGYTVVEASTVVATHLNHLISQHAAELFGRQE
                     AQQLLDRVAQEMPKLTEDLVPGVVTLTTLHKVLQNLLDEKVPIRDMRTILETLAEHAP
                     IQSDPHELTAVVRVALGRAITQQWFPGKDEVHVIGLDTPLERLLLQALQGGGGLEPGL
                     ADRLLAQTQEALSRQEMLGAPPVLLVNHALRPLLSRFLRRSLPQLVVLSNLELSDNRH
                     IRMTATIGGK"
     gene            complement(6671..7819)
                     /gene="flhB"
                     /locus_tag="RHX21_003143"
     CDS             complement(6671..7819)
                     /gene="flhB"
                     /locus_tag="RHX21_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FlhB"
                     /protein_id="HDV1988295.1"
                     /translation="MSDESDDKTEAPTPHRLEKAREEGQIPRSRELTSLLILLVGVSV
                     IWFGGVSLARRLSGMLSAGLHFDHSIIKDPNLILGQIILLIREAMLALLPLISGVVLV
                     ALISPVMLGGLVFSGKSLQPKFSKLNPLPGIKRMFSAQTGAELLKAILKTILVGSVTG
                     FFLWHHWPQMMRLMAESPITAMGNAMDLVGLCALLVVLGVIPMVGFDVFFQIFSHLKK
                     LRMSRQDIRDEFKQSEGDPHVKGRIRQMQRAAARRRMMADVPKADVIVNNPTHYSVAL
                     QYDENKMSAPKVVAKGAGLVALRIREIGAENNVPTLEAPPLARALYRHAEIGQQIPGQ
                     LYAAVAEVLAWVWQLKRWRLAGGQRPVQPTHLPVPEALDFINEKPTHE"
     gene            complement(8021..8665)
                     /gene="cheZ"
                     /locus_tag="RHX21_003144"
     CDS             complement(8021..8665)
                     /gene="cheZ"
                     /locus_tag="RHX21_003144"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase CheZ"
                     /protein_id="HDV1988296.1"
                     /translation="MMQPSIKPADEHSAGDIIARIGSLTRMLRDSLRELGLDQAIAEA
                     AEAIPDARDRLYYVVQMTAQAAERALNSVEASQPHQDQMEKSAKALTQRWDDWFADPI
                     DLADARELVTDTRQFLADVPAHTSFTNAQLLEIMMAQDFQDLTGQVIKRMMDVIQEIE
                     RQLLMVLLENIPEQESRPKRENQSLLNGPQVDTSKAGVVASQDQVDDLLDSLGF"
     gene            complement(8676..9065)
                     /gene="cheY"
                     /locus_tag="RHX21_003145"
     CDS             complement(8676..9065)
                     /gene="cheY"
                     /locus_tag="RHX21_003145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis response regulator CheY"
                     /protein_id="HDV1988297.1"
                     /translation="MADKELKFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALN
                     KLQAGGYGFVISDWNMPNMDGLELLKTIRADGAMSALPVLMVTAEAKKENIIAAAQAG
                     ASGYVVKPFTAATLEDKLNKIFEKLGM"
     gene            complement(9080..10129)
                     /gene="cheB"
                     /locus_tag="RHX21_003146"
     CDS             complement(9080..10129)
                     /gene="cheB"
                     /locus_tag="RHX21_003146"
                     /EC_number="3.1.1.61"
                     /EC_number="3.5.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate methylesterase/protein
                     glutamine deamidase"
                     /protein_id="HDV1988298.1"
                     /translation="MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDL
                     IKKFNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVVMVSSLTGKGSEVTLRALELGAI
                     DFVTKPQLGIREGMLAYSEMIAEKVRTAAKASLAAHKPLSAPTTLKAGPLLSSEKLIA
                     IGASTGGTEAIRHVLQPLPLSSPALLITQHMPPGFTRSFADRLNKLCQIGVKEAEDGE
                     RVLPGHAYIAPGDRHMELARSGANYQIKIHDGPAVNRHRPSVDVLFHSVAKQAGRNAV
                     GVILTGMGNDGAAGMLAMRQAGAWTLAQNEASCVVFGMPREAINMGGVCEVVDLSQVS
                     QQMLAKISAGQAIRI"
     gene            complement(10132..10992)
                     /gene="cheR"
                     /locus_tag="RHX21_003147"
     CDS             complement(10132..10992)
                     /gene="cheR"
                     /locus_tag="RHX21_003147"
                     /EC_number="2.1.1.80"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HDV1988299.1"
                     /translation="MTSSLPCGQTSLLLQMTERLALSDAHFRRISQLIYQRAGIVLAD
                     HKRDMVYNRLVRRLRSLGLTDFGHYLNLLESNQHSGEWQAFINSLTTNLTAFFREAHH
                     FPLLADHARRRSGEYRVWSAAASTGEEPYSIAMTLADTLGTAPGRWKVFASDIDTEVL
                     EKARSGIYRHEELKNLTPQQLQRYFMRGTGPHEGLVRVRQELANYVDFAPLNLLAKQY
                     TVPGPFDAIFCRNVMIYFDQNTQQEILRRFVPLLKPDGLLFAGHSENFSHLERRFTLR
                     GQTVYALSKD"
     gene            complement(11011..12612)
                     /gene="tap"
                     /locus_tag="RHX21_003148"
     CDS             complement(11011..12612)
                     /gene="tap"
                     /locus_tag="RHX21_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein IV"
                     /protein_id="HDV1988300.1"
                     /translation="MFNRIRISTTLFLILILCGILQIGSNGMSFWAFRDDLQRLNQVE
                     QSNQQRAALAQTRAVMLQASTALNKAGTLTALSYPADDIKTLMTTARASLTQSTTLFK
                     SFMAMTAGNEHVRGLQKETEKSFARWHNDLEHQATWLESNQLSDFLTAPVQGSQNAFD
                     VNFEAWQLEINHVLEAASAQSQRNYQISALVFISMIIVAAIYISSALWWTRKMIVQPL
                     AIIGSHFDSIAAGNLARPIAVYGRNEITAIFASLKTMQQALRGTVSDVRKGSQEMHIG
                     IAEIVAGNNDLSSRTEQQAASLAQTAASMEQLTATVGQNADNARQASELAKNAATTAQ
                     AGGVQVSTMTHTMQEIATSSQKIGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGF
                     AVVAGEVRNLASRSAQAAKEIKGLIEESVNRVQQGSKLVNNAAATMIDIVSSVTRVND
                     IMGEIASASEEQQRGIEQVAQAVSQMDQVTQQNASLVEEAAVATEQLANQADHLSSRV
                     AVFTLEEHEVARHESVQLQIAPVVT"
     gene            complement(12658..14319)
                     /gene="tar"
                     /locus_tag="RHX21_003149"
     CDS             complement(12658..14319)
                     /gene="tar"
                     /locus_tag="RHX21_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein II"
                     /protein_id="HDV1988301.1"
                     /translation="MINRIRVVTLLVMVLGVFALLQLISGSLFFSSLHHSQKSFVVSN
                     QLREQQGELTSTWDLMLQTRINLSRSAVRMMMDSSNQQSNAKVELLDSARKTLAQAAT
                     HYKKFKSMAPLPEMVATSRNIDEKYKNYYTALTELIDYLDYGNTGAYFAQPTQGMQNA
                     MGEAFAQYALSSEKLYRDIVTDNADDYRFAQWQLAVIALVVVLILLVAWYGIRRMLLT
                     PLAKIIAHIREIAGGNLANTLTIDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIY
                     AGTREIAAGNTDLSSRTEQQASALEETAASMEQLTATVKQNADNARQASQLAQSASDT
                     AQHGGKVVDGVVKTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGR
                     GFAVVAGEVRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMNNIVNAVTRV
                     TDIMGEIASASDEQSRGIDQVALAVSEMDRVTQQNASLVQESAAAAAALEEQASRLTQ
                     AVSAFRLAASPLTNKPQTPSRPASEQPPAQPRLRIAEQDPNWETF"
     gene            complement(14464..14967)
                     /gene="cheW"
                     /locus_tag="RHX21_003150"
     CDS             complement(14464..14967)
                     /gene="cheW"
                     /locus_tag="RHX21_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HDV1988302.1"
                     /translation="MTGMTNVTKLASEPSGQEFLVFTLGDEEYGIDILKVQEIRGYDQ
                     VTRIANTPAFIKGVTNLRGVIVPIVDLRIKFSQVDVDYNDNTVVIVLNLGQRVVGIVV
                     DGVSDVLSLTAEQIRPAPEFAVTLSTEYLTGLGALGDRMLILVNIEKLLNSEEMALLD
                     SAASEVA"
     gene            complement(14988..16952)
                     /gene="cheA"
                     /locus_tag="RHX21_003151"
     CDS             complement(14988..16952)
                     /gene="cheA"
                     /locus_tag="RHX21_003151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HDV1988303.1"
                     /translation="MSMDISDFYQTFFDEADELLADMEQHLLVLQPEAPDAEQLNAIF
                     RAAHSIKGGAGTFGFSVLQETTHLMENLLDEARRGEMQLNTDIINLFLETKDIMQEQL
                     DAYKQSQEPDAASFDYICQALRQLALEAKGETPSAVTRLSVVAKSEPQDEQSRSQSPR
                     RIILSRLKAGEVDLLEEELGHLTTLTDVVKGADSLSAILPGDIAEDDITAVLCFVIEA
                     DQITFETVEVSPKISTPPVLKLAAEQAPTGRVDREKTTRSNESTSIRVAVEKVDQLIN
                     LVGELVITQSMLAQRSSELDPVNHGDLITSMGQLQRNARDLQESVMSIRMMPMEYVFS
                     RYPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDHGIELPEKR
                     LAAGKNSVGNLILSAEHQGGNICIEVTDDGAGLNRERILAKAASQGLTVSENMSDDEV
                     AMLIFAPGFSTAEQVTDVSGRGVGMDVVKRNIQEMGGHVEIQSKQGTGTTIRILLPLT
                     LAILDGMSVRVADEVFILPLNAVMESLQPREADLHPLAGGERVLEVRGEYLPIVELWK
                     VFNVAGAKTEATQGIVVILQSGGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAAT
                     ILGDGSVALIVDVSALQAINREQRMANTAA"
     gene            complement(16957..17883)
                     /gene="motB"
                     /locus_tag="RHX21_003152"
     CDS             complement(16957..17883)
                     /gene="motB"
                     /locus_tag="RHX21_003152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein MotB"
                     /protein_id="HDV1988304.1"
                     /translation="MKNQAHPIIVVKRRKAKSHGAAHGSWKIAYADFMTAMMAFFLVM
                     WLISISSPKELIQIAEYFRTPLATAVTGGDRISNSESPIPGGGDDYTQSQGEVNKQPN
                     IEELKKRMEQSRLRKLRGDLDQLIESDPKLRALRPHLKIDLVQEGLRIQIIDSQNRPM
                     FRTGSADVEPYMRDILRAIAPVLNGIPNRISLSGHTDDFPYASGEKGYSNWELSADRA
                     NASRRELMVGGLDSGKVLRVVGMAATMRLSDRGPDDAVNRRISLLVLNKQAEQAILHE
                     NAESQNEPVSALEKPEVAPQVSVPTMPSAEPR"
     gene            complement(17880..18767)
                     /gene="motA"
                     /locus_tag="RHX21_003153"
     CDS             complement(17880..18767)
                     /gene="motA"
                     /locus_tag="RHX21_003153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor stator protein MotA"
                     /protein_id="HDV1988305.1"
                     /translation="MLILLGYLVVLGTVFGGYLMTGGSLGALYQPAELVIIAGAGIGS
                     FIVGNNGKAIKGTLKALPLLFRRSKYTKAMYMDLLALLYRLMAKSRQMGMFSLERDIE
                     NPRESEIFASYPRILADSVMLDFIVDYLRLIISGHMNTFEIEALMDEEIETHESEAEV
                     PANSLALVGDSLPAFGIVAAVMGVVHALGSADRPAAELGALIAHAMVGTFLGILLAYG
                     FISPLATVLRQKSAETSKMMQCVKVTLLSNLNGYAPPIAVEFGRKTLYSSERPSFIEL
                     EEHVRAVKNPQQQTTTEEA"
     gene            complement(18894..19472)
                     /gene="flhC"
                     /locus_tag="RHX21_003154"
     CDS             complement(18894..19472)
                     /gene="flhC"
                     /locus_tag="RHX21_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar transcriptional regulator FlhC"
                     /protein_id="HDV1988306.1"
                     /translation="MSEKSIVQEARDIQLAMELITLGARLQMLESETQLSRGRLIKLY
                     KELRGSPPPKGMLPFSTDWFMTWEQNVHASMFCNAWQFLLKTGLCNGVDAVIKAYRLY
                     LEQCPQAEEGPLLALTRAWTLVRFVESGLLQLSSCNCCGGNFITHAHQPVGSFACSLC
                     QPPSRAVKRRKLSQNPADIIPQLLDEQRVQAV"
     gene            complement(19475..19825)
                     /gene="flhD"
                     /locus_tag="RHX21_003155"
     CDS             complement(19475..19825)
                     /gene="flhD"
                     /locus_tag="RHX21_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416406.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar transcriptional regulator FlhD"
                     /protein_id="HDV1988307.1"
                     /translation="MHTSELLKHIYDINLSYLLLAQRLIVQDKASAMFRLGINEEMAT
                     TLAALTLPQMVKLAETNQLVCHFRFDSHQTITQLTQDSRVDDLQQIHTGIMLSTRLLN
                     DVNQPEEALRKKRA"
BASE COUNT         4777 a         5542 c         4922 g         4846 t
ORIGIN      
        1 acgctatgcg cactgtcacc cgctcaacag atcacggtta tcgttcgttt tttatactgc
       61 tcagggataa aaaaaggccc ctgttgaaat tgcaggggcc tggtacgagc aagcatcata
      121 ttgggcgaca tgatgcaacg gtaaaaatca tttggcctga tggcgttcaa tgattccttt
      181 catttcagca accgccgccc cgtctacgac ataacgcgaa tactcgtccg cgtgtgcatc
      241 tgatgacata gacaatcctt gattacgata acgcatcggt gaggcttgcc acgctcccgc
      301 ggagctatgg acttccagca ctccggcatc gaggaagtgg tgcaggtttt ctgcacggac
      361 tcctgctccg gccataatga ttggagcatc acgatgggca ataagttcca taatttttga
      421 taaaccttgc agtgcgtctg atttttgccc tgatgtcagc acccgggcaa tgcccaattc
      481 cgcaagatta ttgagtgtat ttagagggtt agcgcacata tcaaaggcgc gatgaaaagt
      541 cactgccagc ggaccggcag cagccattat tttttccatt cgtggcatat cgacattccc
      601 gtcaacatcg agaacgcccg tcaccagtcc aggaaaacct aattcgcgga ccgtgcgcac
      661 atcctcaaga atggcggcaa actcaccgtc gctgtagcaa aaatcaccac cgcgtgggcg
      721 aattatcgga tgcacaggga tcgtcacccg ctggcgcacg gatttcagta cacccaacga
      781 cggcgttaag cccccctctt ttggggctgc gcataattca actctgtctg cgccgttttg
      841 ctgcgccgtt agtgcacatt ccatgctgta acagcaaatt tccagtaatg ccatttttac
      901 tccttaatta cgccgactgc tcgctggcaa cgatctcttc aatggaccac ggatgaaact
      961 taatagttgt tttgccatcg gtgaccgcca gcgtcggatt cggtaatcgc tcatgctcac
     1021 cttttggcga actggttttc actgagatcc ccggtaggct gagtccttca tcagaaagca
     1081 atgccagcgc acgggcattc agcgtttctg gatcacccgg cagaacgatt tcaatatgtt
     1141 cccaaccttc gtgtgggtaa cgtttttccc cgggccacgg tagctccaca atagaaaact
     1201 gccagtgcgc aacctgtacc ggttcatgca atttaaacag acaaatcggt ctgccattga
     1261 tcatattttc tgacaaaagc tcgccacact gttcaaaccc gcgacgccag cgttcagcag
     1321 tggcgttttg atggcaacgc aaagaaatgt gatcggcagt cagcggagtg atattcaacc
     1381 ccagacggcg ggaaagttca tctaatgcgt gggtaaatcg cggtaaatcc gatgcaatat
     1441 cctgcaactc gtcgatagat tgccagttcg ccataatcac tcttcgtctt tcagtaaaag
     1501 cgttaattta ccctgttgcc ctgtgccaac caaccgctga tttcacgccg cttctgatgc
     1561 aatagtgaaa acggcaatac gccacgcgca cgttgctgac gaaaacagcc atttgcagta
     1621 tactcccgcc ctaatttctt taactggtgc gggcaatttt tgctcgcttc atcaatgtaa
     1681 ggtattccgg tgaatattca ggctcttctc tcagaaaaag tccgtcaggc catgattgcg
     1741 gcaggcgcgc ctgcggattg cgaaccgcag gttcgtcagt cagcaaaagt tcagttcggc
     1801 gactatcagg ctaacggcat gatggcagtt gctaaaaaac tgggtatggc accgcgacaa
     1861 ttagcagagc aggtgctgac tcatctggat cttaacggta tcgccagcaa agttgagatc
     1921 gccggtccag gctttatcaa cattttcctt gatccggcat tcctggctga acatgttcag
     1981 caggcgctgg cgtccgatcg tctcggtgtt gctacgccag aaaaacagac cattgtggtt
     2041 gactactctg cgccaaacgt ggcgaaagag atgcacgtcg gtcacctgcg ctctaccatt
     2101 attggtgacg cagcagtgcg tactctggag ttcctcggtc acaaagtgat tcgcgcaaac
     2161 cacgtcggcg actggggcac tcagttcggt atgctgattg catggctgga aaagcagcag
     2221 caggaaaacg ccggtgaaat ggagctggct gaccttgaag gtttctaccg cgatgcgaaa
     2281 aagcattacg acgaagatga agagtttgcc gagcgtgcac gtaactacgt ggtaaaactg
     2341 caaagcggtg acgaatattt ccgcgagatg tggcgcaaac tggtcgacat caccatgacg
     2401 cagaaccaga tcacttacga tcgtctcaac gtgacgctga cccgtgatga cgtgatgggc
     2461 gaaagcctct acaacccaat gctgccagga attgtggcgg atctcaaagc caaaggtctg
     2521 gcagtagaaa gcgaaggggc gaccgttgta ttccttgatg agtttaaaaa caaggaaggc
     2581 gaaccgatgg gcgtgatcat tcagaagaaa gatggcggct atctctacac caccactgat
     2641 atcgcctgtg cgaaatatcg ttatgaaaca ctgcatgccg atcgcgtgct gtattacatc
     2701 gactcccgtc agcatcaaca cctgatgcag gcatgggcga tcgtccgtaa agcaggctat
     2761 gtaccggaat ccgtaccgct ggaacaccac atgttcggca tgatgctggg taaagacggc
     2821 aaaccgttca aaacccgcgc gggtggtaca gtgaaactgg ccgatctgct ggatgaagcc
     2881 ctggaacgtg cacgccgtct ggtggcagaa aagaacccgg atatgccagc cgacgagctg
     2941 gaaaaactgg ctaacgcggt tggtattggt gcggtgaaat atgcggatct ctccaaaaac
     3001 cgcaccacgg actacatctt cgactgggac aacatgctgg cgtttgaggg taataccgcg
     3061 ccatacatgc agtatgcata cacgcgtgta ttgtccgtgt tccgtaaagc agaaattgac
     3121 gaagagcaac tggctgcagc tccggtaatc atccgtgaag atcgtgaagc gcaactggca
     3181 gctcgcctgc tgcagtttga agaaaccctc accgtggttg cccgtgaagg tacgccgcat
     3241 gtgatgtgtg cttacctgta cgatctggcc ggtctgttct ctggcttcta cgagcactgc
     3301 ccgatcctca gcgcagaaaa cgaagaagtg cgtaacagcc gtctgaaact ggcacaactg
     3361 acggcgaaga cgctgaagct gggtctggat acgctgggta ttgagactgt agagcgtatg
     3421 taatcgattt ttcgtgagag tgaagcctga tcagggttac ctgatcaggc ttttttattg
     3481 ccatctaaat gtattctgaa aatggacatg ccatcgtttt ctcactgttg ggtaagaagt
     3541 cagaagcgta atatccggcc ccagggaaac gataacggtt gaatttaagg aataccgcag
     3601 tgtttaaatt tcttgtatta acattaggca ttatctcttg ccaggtttac gcagaagata
     3661 cgcttatagt aaacgaccat gacatttcag ccatcaaaga ttgttggcaa aaaaattcag
     3721 atgatgatag tgacattaac gtgatcaaat catgcctgcg acaagaatac aatctcgtcg
     3781 atgcgcaatt aaataaagcc tatggtgaag cttatcgtta tatagaacaa gtgccacgca
     3841 caggtgtaaa aaaacctgat accgaacaac ttaacttgct taaaaaatca cagcgagcct
     3901 ggctggattt tagggacaaa gaatgtgaat taatcctttc aaatgaggac gttcaggatt
     3961 taagtgaccc ttattctgaa tcagaatggc tctcatgtat gatcatacag accaatacgc
     4021 gaactcgcca gttgcagcta taccgtaact ctgaagattt ttatccaagc cctttgacaa
     4081 gaggataatt cacatatttt tggcatgttt tgttgcaagc tattcctgat aaataattgc
     4141 aacaaaacat cgagcctttt tcactgagtt attaaacata ctcgcgagcg cgtaattttt
     4201 ttgtccttca gcgataattc acaatcactt cattacgttg tactttcagc ggcggaatta
     4261 accgcccacc gccaggcact tcccagataa agcgcaacgg ttctgctgcc gctataccgg
     4321 aaaaggccac ggtggttccg ctctgcccct ctaattcgac acaacgagat tgcgaacaca
     4381 agcgaacccg cagtcctgaa ggtgtcgggc cgataagctg ataacgccac gctaccagcg
     4441 tcatcaatcc tgaagcaggt tgtcgcgtag aaagaggcgc agacgacatc gactcaccgc
     4501 gatgatttag cgtaattcct acactacttg cctgccacat cccctccccg gcggcttgca
     4561 ccagcagcgg aaacaataat attgctaata aggttctcat tatttgccgc caattgtcgc
     4621 cgtcatgcgg atatgtcggt tatcagacag ttccagattc gacaggacca ctaactgcgg
     4681 caagctgcgg cgcaggaagc gagacaataa tggtcgcagc gcgtggttca ccaacaatac
     4741 tggcggcgca cccagcatct cctgacggga tagcgcttcc tgagtttgcg ccagtaaacg
     4801 atccgccagc cctggctcca gtcctccccc gccctgcagc gcctgtagta acaaacgttc
     4861 cagcggtgta tcgaggccaa taacatggac ttcatctttg ccaggaaacc actgctgggt
     4921 aatcgcccgt cccaacgcca cgcgcacgac ggcggttaat tcatgtggat cgctttggat
     4981 gggcgcatgt tccgccagcg tttcgagaat ggtgcgcata tcgcgaatcg gtactttttc
     5041 atcgaggaga ttttgcagca ctttatgcag tgtggtgagc gtgacgacgc caggaacgag
     5101 atcttccgtc agctttggca tctcctgggc gacgcgatcc aacagctgtt gcgcctcctg
     5161 acgaccaaac agctctgcgg catgctggct aatgaggtgg ttaagatgcg ttgctaccac
     5221 cgtgctggcc tcaaccactg tgtacccctg aatctgcgcc tgttctttta gcgcactttc
     5281 aatccagata gcattcaggc caaatgccgg atcgacggtc gcctcaccag gtaacgtccc
     5341 ggcagcggtt ccagggttaa tcgccagcca gcgccccgga taagcatcac cactgccaat
     5401 ctccacgcct ttcatcaaaa tgcgatagcg ggcaggttgc agatccatat tgtcgcgaat
     5461 gtgcaccact ggcggcagaa atcccatctc ctgggcaaat ttcttgcgga tactgcgtat
     5521 acggcccaac aactcaccat cctgctggaa atcgaccatc gggatcagtc gataacccac
     5581 ttccattccc agagaatctt ccagttgtac atcgttccac gtcgcttcga caacggtatt
     5641 attctctgcc atttttaccg gtttgggttc ggcaggcgct ttttgttcgc gtccgcgtat
     5701 ccaccaggcc agcccgagca atccggcagt gaacagcaaa aataccaggt tcggcattcc
     5761 aggcaccagg ccgagtaaac cgagcacggc ggcgcttaac aacataacgc ttgggttact
     5821 gaaaagctga ttcaccatct gctcgccaac atcctgatcg gtgctgacac gcgtaacgat
     5881 gacccccgcg gcggtagaaa tcaccagcgc cggaatttgt gccaccagac cgtcgccaat
     5941 ggtcaatagc gtataacttt ccgccgcgtg tcccatgctc atgccatgtt gcagcacgcc
     6001 gaccagcaac ccgccgacaa tgttaatgac catgatgagg atcccggcga tggcatcgcc
     6061 gcgaacaaac ttacttgccc cgtccattga gccgtaaaaa tcggcttcct gagtcacttc
     6121 ggagcggcgt tttttcgcct catcttcacc aatcaatccg gcgttaaggt cggcgtcaat
     6181 cgccatctgc ttacccggca taccatcgag aacaaagcgc gcacccactt ctgcgatacg
     6241 cccggcacct ttggtaatga ccataaagtt gatgatcacg agaatgacaa acaccacgat
     6301 accgatagcg aaattgccac caacgaggaa gtgaccgaac gcttcgacca ccttccctgc
     6361 cgccgccgcg ccggtatgcc cttccattaa aatgatacgg gttgaagcca cgttaagtgc
     6421 cagacgcaac agcgtggtaa acaacagaat ggtcggaaac gcagcaaact caagcgtgcg
     6481 ctgggtaaac atcgccacca gcaacaccat gatcgacaag gcaatattga aggtaaacaa
     6541 caggtcgagt atgaatgcgg gcagtggcag caccatcatc gacaagatca acaggatcaa
     6601 aatcggtccg gcaaggatct gccattgtgt cgatttcagg tttgcgggca ggcgcagcat
     6661 cgcggccaga ttactcatgg gtcggtttct cgttaataaa atccagggct tccggcaccg
     6721 gaagatgagt aggttgtaca gggcgctgtc caccagccag acgccagcgt ttcagttgcc
     6781 agacccaggc cagcacttcc gccaccgcgg cgtacagttg acccgggatt tgttgaccaa
     6841 tctccgcatg tcgatacagc gctcgcgcca gcggcggcgc ttcaagcgtc gggacgttat
     6901 tttcagcgcc aatttcacga atgcgcagcg cgaccagccc tgcaccttta gcgaccactt
     6961 tcggtgcgct cattttgttt tcgtcatact gcaacgctac cgaatagtgg gtcgggttat
     7021 tgacaatgac atccgctttc ggcacatcgg ccatcatccg acgccgtgcg gcagctcgct
     7081 gcatctgacg gatccgtcct ttaacatggg ggtcgccttc gctttgtttg aactcatcac
     7141 gaatatcctg ccgcgacatt cgcagctttt tcaggtggct gaagatttgg aaaaagacgt
     7201 caaatcccac cattggaatg acaccaagca ccaccagcag tgcgcatagc cctaccaaat
     7261 ccatcgcatt acccatggcg gtaatcggag actcggccat taagcgcatc atctgcggcc
     7321 agtgatgcca gagaaaaaac cccgtcacgc tgccaaccag gatggttttc aaaattgctt
     7381 taagcaactc cgcgccagtc tgagccgaga acatccgttt aatgcccggt agcgggttga
     7441 gtttggaaaa cttcggctgc aaggatttgc cgctaaatac cagccctccc agcatgaccg
     7501 gagaaatgag cgccaccagt accacgccgc taatcagtgg cagcagcgcc agcatggctt
     7561 ctctgatcag cagaataatc tgcccgagga tcagattcgg gtctttgata atactgtgat
     7621 caaaatgcag cccagcggag agcatgcccg acaatcgacg ggccagcgac acaccgccaa
     7681 accagataac actaacgccc accagcaaaa tcagcagtga ggtcagttca cgggaacgcg
     7741 ggatttgccc ctcttcccgc gctttttcta gtcggtgagg tgtgggggct tctgttttgt
     7801 cgtcgctctc gtcagacacg tcgccaatcc tggaaagagt attaagcgtg aatgatgcca
     7861 gagcgcaaag cgttcaatgg tttgagtaag gggcaaaaca ggcgggattt agggcttttg
     7921 ctgccacaca tcaagcatag tgtgcgtttg tcggatgcgg cgtcatcgcc ttatcagacc
     7981 gcctgatatg acgtggtcac gccacatcag gcaatacaaa tcaaaatcca agactatcca
     8041 acaaatcgtc cacctgatcc tgactggcta ccacaccggc tttgctggta tcgacctgag
     8101 gtccattaag caaactctgg ttttcacgtt ttggacgcga ctcctgttcc gggatgtttt
     8161 ccaacagcac catcagcaac tggcgttcga tctcctgaat gacatccatc atccgcttaa
     8221 tgacctgccc ggtgagatcc tgaaaatcct gcgccatcat gatttccagc agttgcgcgt
     8281 tagtaaagct ggtatgcgcg ggtacatctg ccagaaattg tcgtgtatct gttaccagtt
     8341 cacgggcgtc ggcaaggtca atcggatcgg caaaccagtc atcccaacgt tgggttaacg
     8401 cttttgctga tttctccatt tgatcctgat gcggttgtga cgcctcaaca ctgttcagcg
     8461 cccgctccgc agcctgggcg gtcatctgca caacatagta caaacgatcg cgcgcatcgg
     8521 ggatggcttc cgccgcttcg gcaatggcct gatccagccc cagttcccgc aaactgtcgc
     8581 gcagcatacg cgtcaggctg ccgatgcgcg caatgatatc gccagctgaa tgctcgtcag
     8641 caggtttgat tgatggttgc atcatagtcg catcctcaca tgcccagttt ctcaaagatt
     8701 ttgttgagtt tatcctccag cgtcgcggcg gtaaatggct tcaccacata gccactggcc
     8761 cccgcttgcg ccgcagcaat gatgttctct ttcttcgctt ctgcagtcac cattaacact
     8821 ggcaatgccg acatcgcgcc atccgcacga attgttttca gcaattccag gccatccata
     8881 ttgggcatgt tccagtcgga gataacaaat ccataaccgc ctgcctgcaa cttattgaga
     8941 gcgtcgacgc catcttccgc ttcctcaaca ttattgaatc ccagctcttt cagcaggtta
     9001 cgcactatgc gtcgcatggt ggaaaagtca tccacaacca aaaatttaag ttctttatcc
     9061 gccatttcac actcctgatt taaatacgta tcgcctgtcc ggcactaatt tttgccaaca
     9121 tttgctggct tacctggcta agatcgacca cttcgcagac accacccata ttgatggcct
     9181 cgcgcggcat gccgaacacc acgcaacttg cttcgttttg cgcaagggtc catgcccccg
     9241 cctgacgcat cgccaacatt cctgccgcgc cgtcgttgcc cataccggtc aggatcaccc
     9301 caaccgcatt acgccccgcc tgtttggcga cagaatggaa caacacatct accgaaggcc
     9361 gatgacggtt aaccgccggg ccatcatgaa ttttgatttg gtaatttgcg ccactacgcg
     9421 ccagctccat atgccgatcg cccggcgcga tataggcatg ccccggcaaa acacgttctc
     9481 cgtcttcggc ttctttaacc ccgatctgac aaagcttatt aagtctgtcg gcaaaagagc
     9541 gggtgaaacc aggcggcata tgctgggtaa ttaacagtgc cgggctggaa agcggcaacg
     9601 gttgcagtac gtgacgaatt gcctcagttc cacccgttga agcaccaatc gcaatcagtt
     9661 tttcagaact caacaacggc cctgccttca gcgttgtcgg tgccgacaat ggcttatgtg
     9721 ctgcaaggct cgcctttgct gctgtacgca ccttttcagc aatcatttcg ctatacgcca
     9781 gcattccttc gcgaataccc agttgcggtt tggtgacaaa atctatcgcc cccagctcca
     9841 gcgcgcgcag cgtgacttct gaccctttgc cggtcaggga agaaaccatc actacgggca
     9901 ttggacgcaa acgcattaat ttttcgagga aatccagtcc gtccatccgc ggcatttcaa
     9961 catccagcgt cagcacatcg ggattgaatt tcttaatcaa gtcacgcgcg accagcggat
    10021 caggcgcggt cgccaccatt tccatgtcgc tatggctgtt gatgatttct gtcatgatct
    10081 ggcgcatcag tgccgaatca tcgacagata acaccctgat tttgctcatc gttaatcctt
    10141 acttagcgca tacaccgtct gaccacgcag cgtgaagcgg cgctcaaggt ggctaaagtt
    10201 ttcagagtga cccgcaaaca gcaatccgtc gggtttaagg agcggaacaa agcggcgcaa
    10261 aatctcctgc tgggtatttt gatcgaagta gatcatgacg ttacgacaga agatcgcatc
    10321 aaacggcccc ggcacggtgt actgtttcgc cagtagattc agcggggcaa aatcaacata
    10381 gttcgccagc tcctgacgca cgcgtaccag cccttcatgc ggtcccgtcc ctcgcatgaa
    10441 ataccgttgc agttgctgcg gcgtcaggtt tttcaactct tcatggcgat aaataccgct
    10501 tctggctttt tccagcactt cggtgtcgat atcactggca aacactttcc agcgtccggg
    10561 cgcggtgccc aatgtgtcag ccagcgtcat cgcaatgctg tacggctctt cgccggtcga
    10621 agccgccgcg ctccatacgc gatactcgcc agaacggcga cgtgcgtgat ccgcgagcag
    10681 agggaaatgg tgtgcctcac ggaaaaatgc cgtcagattc gtggtcagcg aattgataaa
    10741 cgcctgccac tcaccgctgt gctgattaga ttccagcaag ttcagataat gaccgaaatc
    10801 cgtcagtccc agcgaacgca aacgacgaac cagtcggttg taaaccatgt cgcgtttatg
    10861 gtcagccaga acgatcccgg ctcgttgata gatcaattga cttatccgcc gaaaatgcgc
    10921 gtcggaaagc gccaggcgct cggtcatctg taacaataaa gacgtttgcc cacagggcag
    10981 agatgaagtc atagcgcctt ctcaatcact tcaggttacc actggcgcaa tttgtaactg
    11041 caccgactca tgtcgtgcta cttcatgttc ttcaagggta aataccgcca cacgcgacga
    11101 aagatggtcg gcctgattcg ccagttgttc cgttgccacc gccgcttctt ctaccagcga
    11161 ggcgttctgc tgagtcacct gatccatctg gctgacagcc tgtgcaacct gctcaatccc
    11221 ccgctgttgt tcttccgacg cagaggcaat ttctcccata atgtcgttca cgcgggtcac
    11281 cgaactgaca atatcgatca tggtcgcggc ggcgttattc accagtttcg aaccctgctg
    11341 gacacgattg actgactctt cgatcagccc tttgatctct tttgctgcct gcgcgctacg
    11401 gctggcaaga ttgcgcactt cacctgccac taccgcaaaa ccacgcccct gctctccggc
    11461 gcgagccgct tccactgccg cattcagggc cagaatattg gtctggaaag caattccgtc
    11521 gataacgctg ataatgtcgc caattttttg cgagctggtg gcgatctcct gcatggtgtg
    11581 agtcatggta ctgacctgaa caccgcccgc ctgcgccgtt gtcgcggcat tttttgccag
    11641 ttccgacgcc tgtcgtgcgt tatcggcgtt ttgccctacc gtggcggtta attgctccat
    11701 actggcggcc gtttgtgcca gcgatgccgc ctgctgttcg gtacgacttg agagatcgtt
    11761 attgcctgcg acaatctccg cgataccaat gtgcatctcc tggcttccct tacgcacatc
    11821 acttaccgtc ccacgcaaag cctgctgcat ggtcttcaga ctggcaaaaa tggcggtgat
    11881 ctcattacga ccatataccg caatcggacg cgccagatta cccgcagcaa tgctgtcaaa
    11941 atggctaccg ataatggcca gtggttgaac aatcatcttg cgcgtccacc acagcgcact
    12001 gctgatgtag atcgccgcaa caataatcat gctgataaac accagtgccg aaatctgata
    12061 gttacgctgg ctttgcgcac tggcggcttc cagcacatgg ttgatctcca gctgccaggc
    12121 ctcaaagtta acgtcaaacg cattctgtga tccctgcacc ggcgcagtga ggaaatccga
    12181 aagttgatta ctttcaagcc aggtcgcctg atgttcgaga tcgttgtgcc agcgggcaaa
    12241 acttttctcc gtctcttttt gcaatcccct gacgtgctcg ttgcccgcag tcatcgccat
    12301 aaaactttta aacagcgtgg tggattgcgt cagactggcg cgcgccgtcg tcatcaacgt
    12361 tttaatgtca tccgccggat agctaagtgc cgtcagagtg cccgctttgt tcagcgcggt
    12421 actggcctgt aacattaccg cccgagtttg cgctaatgcc gcacgttgct gattgctctg
    12481 ctcgacctga ttcagtcgtt gcaaatcgtc gcgaaatgcc caaaaagaca tgccgttact
    12541 gccaatctgc aagatcccgc agagaatcaa aattaaaaac agcgtggtcg aaattcgaat
    12601 acgattaaac atcaacgctc cccatcaggc ggcaatgacc gcgttagtaa atactcgtca
    12661 aaatgtttcc cagtttggat cttgttcagc aattcgcagt cgtggctgtg ccggtggttg
    12721 ctcactggca ggacgggatg gtgtttgcgg tttattggtg agtgggctgg ctgccagacg
    12781 gaacgcggaa accgcttgcg ttaaacgact cgcctgttct tccagcgcag cggcggcggc
    12841 agctgattcc tgcaccagcg atgcgttctg ttgcgtgacg cgatccattt ccgaaaccgc
    12901 caatgcgact tgatcgatgc cacggctctg ttcatccgat gccgatgcaa tctcgcccat
    12961 aatgtcagtc acgcgagtga cagcattgac gatattgttc attgtttccc cggcgctttc
    13021 gaccagcacc gaaccggtat caacgcgtga gacggagtct tcaatgaggg ctttaatctc
    13081 ttttgccgcc tgggcgctgc gactggcaag attacgcact tcacccgcca ccacggcaaa
    13141 accacggccc tgttcacccg cacgcgcggc ttcaaccgcg gcattcagcg cgaggatatt
    13201 agtctggaag gcaataccgt cgataacgct gataatgtcg gcaattttct tcgaactatc
    13261 ggcgatctca tgcatcgttt tcactacgcc atccaccact ttgccgccgt gctgggcggt
    13321 gtcggaggca ctttgcgcca gttgcgaggc ctggcgggcg ttatcggcgt tttgcttcac
    13381 tgtcgcggtg agctgctcca tgctggcggc agtttcttcc agcgcggatg cctgctgttc
    13441 agtacgggag gaaagatcgg tgttgcccgc cgcaatttca cgggtaccgg catagatggc
    13501 atctgaacct tcgcggacat gagtgacggt gtcagtcaaa gagcgttgca tatgtgaaac
    13561 gctctgcgcc aggtcgccca tttcactgcg cccgtcaatg gtcagggtat tcgccaggtt
    13621 accaccggcg atttcgcgaa tgtgagcaat aatttttgcc agcggagtaa gcaacatacg
    13681 gcgaatgccg taccacgcca ccagcagaat caataccacc accagcgcga taaccgccag
    13741 ttgccactgg gcaaatcggt aatcatctgc gttgtcagtg acgatatcgc gatacagttt
    13801 ttcactgctg agggcgtact gagcaaacgc ttcgcccatt gcattttgca ttccctgggt
    13861 tggctgagcg aaataagctc cagtattgcc ataatctaga taatcaatca gttcagttaa
    13921 cgctgtgtaa tagtttttat atttttcatc aatattacga ctggtagcga ccatttcagg
    13981 taacggtgcc atgcttttga attttttata atgcgtcgct gcctgcgcca atgttttcct
    14041 ggcgctatcg agcaattcaa ctttggcgtt actttgttga ttggaggaat ccatcatcat
    14101 ccgtaccgct gaacgactca ggttaatgcg cgtttgcagc attaaatccc aggttgacgt
    14161 cagctcgccc tgctgttccc gtaattgatt ggaaaccaca aagctcttct ggctatggtg
    14221 aagggaagaa aaaaacagac tgccggaaat aagctgtaac agtgcgaata cccccagcac
    14281 cattaccaac agcgtgacta cgcggatacg gttaatcata aggcaccttc ctgaaaacaa
    14341 gttgatctcg ttatcggcaa ggagggggga aactttattg ctgatgccac ccgccgcgaa
    14401 attgaaataa aaaacccgat gcgcagatca tcgggttcat ttcaattgag gaaatcggga
    14461 gaattacgcc acttctgacg ccgcgctatc taacagcgcc atctcttcgc tgttcagcag
    14521 tttttcgatg ttcaccagaa tcaacatccg gtcgcccagt gcgcccagtc cagtgagata
    14581 ttctgttgaa agcgtcacgg caaattccgg tgccggacga atttgctccg ccgtcaatga
    14641 aagcacgtct gagacgccgt caaccacgat gccgaccacc cgctgtccga gattcaggac
    14701 gataactacc gtgttgtcgt tatagtccac atccacctgg ctgaacttaa ttcgtaagtc
    14761 aacaatcggc acaataacgc cgcgcagatt cgtgacgcct ttgataaacg ctggcgtgtt
    14821 cgcaatccgt gttacctgat cgtagccacg gatctcctgc actttcagga tatcaatacc
    14881 gtactcttca tcaccaaggg taaataccag aaattcctgg cctgacggct cgctggccag
    14941 ctttgttaca ttcgtcatac cggtcatatt gttacctttt tactcattca ggcggcggtg
    15001 ttcgccatac gttgttcgcg gtttatcgcc tgcaaggcgg agacatcaac aatcagtgcc
    15061 acgctgccgt cgccaagaat ggtcgcagca gaaatgccgg ggactttgcg atagttactt
    15121 tcaaggtttt taaccacaac ctggtgttga ccaattaatt gatccaccag caaggcgtag
    15181 cggcgaccgc cactttgtaa gatcaccaca attccctggg tggcttcggt tttcgcgccc
    15241 gcgacgttga acactttcca cagttcgacg atgggcagat attcaccccg cacttccagc
    15301 acccgctcgc cgccggccag tggatggaga tcggcttcac ggggttgcag tgattccata
    15361 acagcattca gcggcagaat gaaaacttca tccgcaacgc gtacggacat gccgtcgagg
    15421 atggccagcg tcagcggcag taaaatgcgg atcgtagtgc cagtaccctg cttcgactgg
    15481 atttcgacat gaccgcccat ctcctggata ttacgtttga cgacgtccat gccgacgccg
    15541 cgcccggaga cgtcggtgac ctgctctgcc gtggagaagc caggtgcaaa tatcagcatc
    15601 gcgacttcgt cgtcgctcat gttttcgctg acagtcaaac cttgcgaggc cgcttttgcc
    15661 agaattcgct cacggtttag ccccgcccca tcgtcggtca cttcaatgca aatgttgccg
    15721 ccctgatgtt cggcagacag aattaaattt ccgacgctgt ttttacctgc ggcgagccgt
    15781 ttttctggca gttcaatacc gtgatcgagg ctattgcgta ccaggtgggt cagcgggtcg
    15841 ataatgcgtt ctatcaggct tttgtcgagt tcagtagaac tgcccaccag cgtcagttct
    15901 acctgcttgc cgagttttcc cgccagatca cgcaccagcc ggggatagcg actaaaaaca
    15961 tattccatcg gcatcatgcg aatcgacatc actgattcct gcaaatcacg ggcgttacgt
    16021 tgtaactgcc ccatgctggt tatcaaatca ccatgattaa ccgggtccag ttcgctggaa
    16081 cgctgggcaa gcatggactg ggtgataacc agctcgccga cgaggttaat taattgatca
    16141 accttttcta ccgctacacg gatgctggtg gattcattgc tgcgcgtcgt tttttcccga
    16201 tccacgcggc cggttggcgc ttgttcggct gccagtttaa gcactggtgg ggtggatatt
    16261 tttggcgaga cttctactgt ttcaaaggta atctgatcgg cttcaatcac aaaacagagt
    16321 accgctgtga tgtcatcttc ggcgatgtcg cccggtaata ttgccgagag cgaatccgcc
    16381 cctttcacca cgtcagttaa cgttgtcaga tgtcccagtt cttcttccag caggtcgact
    16441 tccccggcct tcaggcgcga aaggataatt cgtcgcggcg actgactgcg actctgctca
    16501 tcttgcggtt cacttttggc aaccacactt aatcgggtca ctgcggatgg cgtttcgcct
    16561 ttcgcttcta atgccagttg acgcaaggcc tggcagatat aatcgaagct ggcggcatcc
    16621 ggctcttgcg actgtttata agcgtcgagc tgttcttgca tgatgtcctt cgtttccaaa
    16681 aacagattga taatgtcggt gttgagttgc atctcacctc gtctggcttc atcgagcagg
    16741 ttttccatca gatgcgtggt ttcctgcaaa acgctgaagc caaaagttcc tgcccctcct
    16801 ttgatcgagt gggcagcccg aaagatggca ttcaattgtt cggcatctgg cgcttccggc
    16861 tgcaaaacca gcaaatgctg ctccatgtca gccaacagtt cgtccgcttc atcaaaaaat
    16921 gtctgataaa aatcgcttat atccatgctc acgctgtcac ctcggttcgg ctgatggcat
    16981 tgtgggaaca ctgacctgtg gtgcaacctc aggtttttcc agggcgctta ctggctcatt
    17041 ctggctttcg gcgttttcat gcaaaatggc ctgttcggct tgtttgttca gtaccagcag
    17101 gctgatgcga cggttgacgg catcatcagg tccgcgatcg cttaagcgca tcgttgccgc
    17161 catgccgacg acacgtaaca ctttgccgct atccaaccct ccgaccatca gttcgcggcg
    17221 ggatgcattg gcccgatcgg cagaaagctc ccagttgcta tatcctttct caccgctggc
    17281 gtaggggaaa tcatcggtat gacctgaaag gctaatacgg ttgggaatac cgttcagtac
    17341 aggcgcaatg gcgcgcagaa tgtcgcgcat atagggttcg acatcggcac tgccggttct
    17401 aaacatcggg cgattctggc tatcgatgat ctgaatacgt agaccttcct ggaccagatc
    17461 gattttgaga tggggacgta acgcccgcag tttcggatcg gactctatca actggtcgag
    17521 atcaccccgc aatttccgca atcgactttg ctccatgcgt tttttcagct cttcgatgtt
    17581 cggctgctta ttcacttccc cctggctttg ggtgtaatca tcaccaccgc cgggaattgg
    17641 gctttcacta ttagaaatgc gatcgccgcc cgtaaccgca gtcgccagtg gagtccggaa
    17701 gtactccgca atctgaatca gctcttttgg gctggagatg gagatcagcc acatcaccag
    17761 aaaaaaggcc atcatcgcag tcataaagtc ggcataagca atcttccacg atccatgtgc
    17821 tgccccgtgg cttttggctt tgcgtcgttt gacgacaata atcggatgcg cttgattctt
    17881 catgcttcct cggttgtcgt ctgttgttgc ggatttttca ccgcacgcac atgctcttcc
    17941 agttcaataa acgacggacg ttcgctggaa tagagcgttt tgcgaccaaa ctcaacggcg
    18001 ataggcggtg cgtaaccgtt cagattagaa agcagagtga ctttgacgca ctgcatcatt
    18061 ttgctggttt cggcgctttt ctgacgtaaa acagtcgcta atggggaaat aaatccgtaa
    18121 gccaataaaa tgccgaggaa agtccccacc atcgcatgtg cgataagcgc acccagctcg
    18181 gcggcaggac gatcggctga acctaacgcg tgaacgaccc ccattacagc cgcaacaata
    18241 ccaaacgccg gaagtgagtc cccgaccagc gccagactgt tcgccgggac ttctgcctcg
    18301 ctttcgtgcg tctcaatctc ttcatccatc agggcttcga tttcgaaggt gttcatgtga
    18361 ccgctgataa tcaggcgcag ataatcgacg ataaaatcaa gcatgacgct atccgcgagg
    18421 atgcgtgggt agctggcgaa gatctcgctc tcacggggat tttcaatatc acgttccagc
    18481 gaaaacatcc ccatctgccg cgatttcgcc atcaaccgat aaagcagagc cagcagatcc
    18541 atatacattg ctttggtgta tttggagcga cgaaacagca acggcagcgc cttcagcgtg
    18601 cctttaatcg ctttgccatt attgccgacg ataaacgacc caatccctgc accggcaata
    18661 atcaccagtt cagcgggttg atagagtgct ccaaggcttc caccggtcat caaataaccg
    18721 ccgaaaactg taccgagaac aaccaggtaa cctaataaga taagcacgac atcatccttc
    18781 cactgttgac catgacagga tgttcagtcg tcaggcgtta acgcgcgatt ggggcaaaaa
    18841 aaagcagcgg tacgtcgtta ccgctgctgg aatgttgcgc ctcaccgtat cagttaaaca
    18901 gcctgtactc tctgttcatc cagcagttgt gggataatat cggcaggatt ctgggaaagt
    18961 ttacgtcttt ttactgcccg ggatggcggt tgacataagc tgcaggcaaa gctgccaaca
    19021 ggctggtgag cgtgggtaat aaaattgccg ccgcagcagt tgcagctgga aagttgcagt
    19081 aatccacttt caacaaaccg caccaatgtc caggcacggg ttaatgccag cagtggtcct
    19141 tcttctgctt gtgggcactg ttcaaggtat aaacggtagg ctttgatcac cgcatcgacg
    19201 ccattacaca aaccggtttt cagtaaaaac tgccatgcat tacagaacat cgaagcatga
    19261 acgttttgtt cccaggtcat aaaccagtcg gttgagaatg gcagcatgcc tttcggcggt
    19321 gggcttccgc gcagttcttt ataaagtttt atcaggcgtc cgcgacttaa ctgtgtttcg
    19381 ctttccagca tctgcaaacg agcgcccagg gtgatcaatt ccattgccag ctgaatatcc
    19441 cgcgcttcct gaacaatgct tttttcactc atgatcaggc ccttttcttg cgcagcgctt
    19501 cttcaggctg attaacatca ttcagcaagc gtgttgagag catgatgccg gtatgaattt
    19561 gctggagatc gtcaacgcgg gaatcttgcg tcaactgagt aatcgtctgg tggctgtcaa
    19621 aacggaagtg acaaaccagt tgattggttt ctgccagctt aaccatttgc ggaagagtca
    19681 gtgccgctaa cgttgtcgcc atttcttcat ttatgccgag acgaaacata gcggacgctt
    19741 tgtcctgaac aatcaaacgc tgtgcaagta gtaaatatga caagttgatg tcataaatgt
    19801 gtttcagcaa ctcggaggta tgcattattc ccacccagaa taaccaactt tatttttatg
    19861 cggtttcacc gcaccccgtg atgtcgccgg gaagccccgg taaaaaataa ttagcattag
    19921 aatagttgcg ataagctgca ataagcagaa ccaccttttt ggtttaatat gtccttacaa
    19981 atagaaatga gtctttacac ttatctaaga tttttcctaa atcgacgcaa ctgtactcgt
    20041 cactacacgc acatacaacg gaggggggct gcgattttca ataatgt
//
LOCUS       DAPGUL010000082        19554 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.083, whole genome shotgun sequence.
ACCESSION   DAPGUL010000082 DAPGUL010000000
VERSION     DAPGUL010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19554
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.083"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            216..716
                     /gene="tssB"
                     /locus_tag="RHX21_003156"
     CDS             216..716
                     /gene="tssB"
                     /locus_tag="RHX21_003156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     small subunit"
                     /protein_id="HDV1988308.1"
                     /translation="MSKKFEGSVAPRERINISYVPKTDGQTAEVELPLNMLVVGDTGN
                     TQETSSLDERQAVSVNKHNFGAVMAEAAIGLNFTVPATLKGSTTDDELNVALNIKSLD
                     DFSPDSVARQVPEVNKLLELREALTALKGPMGNLPAFRTQLQALLENEESREQLLKEI
                     GQVSNK"
     gene            751..975
                     /locus_tag="RHX21_003157"
     CDS             751..975
                     /locus_tag="RHX21_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988309.1"
                     /translation="MTAHKNISGTYHLSVADILQVVYQVCFSPSVEINQDGVAALITT
                     LDRRISDLLDEIIHFCEFQQSASHWQRVLH"
     gene            1026..2501
                     /gene="tssC"
                     /locus_tag="RHX21_003158"
     CDS             1026..2501
                     /gene="tssC"
                     /locus_tag="RHX21_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001501045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     large subunit"
                     /protein_id="HDV1988310.1"
                     /translation="MSLQEEELVSSHAGQPEQASSLLDQIMAQTRIQPGSEGYDVARQ
                     GVTAFIASILQSTASAEPVNKLAVDSMIADIDERISRQMDVIIHAPAFQQVESFWRSL
                     KTMVDRVDFRENIKVNVLHVIKQELLEDFEFAPEIIQSGFYKHVYSSGFGQFGGEPIA
                     AVLGAYEFKNTAPDMKLLQYVSAVGAMAHAPFLSSVSPEFMGLNSWTELPNIKDLYAI
                     FEGPAYTKWRALRDSEDSRYLGLTAPRFLLRQPYSPTDNPVKNFNYYEDVSQNHEDYL
                     WGNTAWMLACNIADSFAKYRWCPNIIGPQSGGAVKDLPVHLFETMGQIQAKIPTEVLV
                     TDRREFELAEEGFITLTMRKDSDNAAFFSANSVQKPKHFPGKDAETNYKLGTQLPYLF
                     IINRLAHYIKVLQREQLGSWKERSDLERELNTWIRQYVADQENPPADVRSRKPLRAAK
                     VEVMDVEGEPGWYQVALSVRPHFKFMGANFELSLVGRLDRE"
     gene            2508..2921
                     /gene="tssE"
                     /locus_tag="RHX21_003159"
     CDS             2508..2921
                     /gene="tssE"
                     /locus_tag="RHX21_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssE"
                     /protein_id="HDV1988311.1"
                     /translation="MIPDRERTTGSLFERMEASSARNRQGGSIHSLRQSIRQNLRNIL
                     NTRSGSCRGAPELGIDEPEGAENFRESMSRAIEQCIERYEPRISHAEVQAVVSSASSP
                     LDMTFHITAWVTFNETHEVLEFDMAPNGSQHYRVD"
     gene            2925..4775
                     /gene="tssF"
                     /locus_tag="RHX21_003160"
     CDS             2925..4775
                     /gene="tssF"
                     /locus_tag="RHX21_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssF"
                     /protein_id="HDV1988312.1"
                     /translation="MEFEERYFREELDYLRQLSKLLATEKPHLARFLAEKDADPDIER
                     LLEGVAFLTGNLRQKIEDEFPELTHGLIKMLWPNYLRPVPAMTLIEYTPDMDKSSVPV
                     LIPRNEQFTTNAGEIRVDEVLPSDAKKEEPPPCTFTLCRDIWLLPVRLEQIENRSTTR
                     NGVINITFSVAPGTDFRTLDLNKLRFWLGNDDNYTRDQLYLWFCEYLQGADLTVGEQH
                     IRLPEFMLKAVGFEPQDAMLPWPKNVHSGYRILQEYFCYPDAFLFFDLCGCPALPDGL
                     QAEFFTLQLRFSRPLPVDIRLRRDSLRLYCAPAINLFIHHAEAITLDNRRADYPLVPS
                     RHYPQHYDVFSVNSVVSQVQDMFRKKDLGRPVSTQAARQWPAFESFSHQMEYSRKREV
                     VYWHHRTKTSLFHRGFDHTLAFIHADGSYPSDESLLSNEVVSVSLTCTNRELPSQIRS
                     GDITGTTGKNAAVASFRNITRPTQPLWPVIDGSLHWSLLSAMNLNYLSLLDTDALKQV
                     IANFDRHAIHHPQTARLSQQKLDAIERLETRPVDRLFTGIPVRGLASTLYLHPEPFVC
                     EGEMYLLGTVLSHFLSLYASVNSFHMLTVVNTESQETWKWTERIGQHPLI"
     gene            4739..5821
                     /gene="tssG"
                     /locus_tag="RHX21_003161"
     CDS             4739..5821
                     /gene="tssG"
                     /locus_tag="RHX21_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssG"
                     /protein_id="HDV1988313.1"
                     /translation="MDGKNRAASSYLSPGNPPADKEQNDPLAQVFHNACSYNFFAMAE
                     LLHRLAKGEKGTPELSLRDDPAQETLRFSADASLAFPCSDISALKRDTSGAFRMTTTF
                     MGLQGSQSPLPGYYLDHLAWKAVHEQSPVGDFLDMFSHRLTQFVWHIWRKYRYHISFR
                     NGGVDAFSQRMYSLVGLGHRQLRDKLAINHSKMLAYSGILANPGRSPEIICGLVSHCF
                     DLSEVTLQNWQRRKVDIEPDQQNSLGSYSLKNGEKLAGRSVLGNFVLGTRVPDLSGKF
                     QLSITSLTRKQFLSFLPSGENFLPLTMFVSFILRDQLAWDLHLGLAPEQVGAMRLGDN
                     KSALLGWTSFLGTPEERPSVTIRVRS"
     gene            5846..7126
                     /gene="tagH"
                     /locus_tag="RHX21_003162"
     CDS             5846..7126
                     /gene="tagH"
                     /locus_tag="RHX21_003162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system-associated FHA domain
                     protein TagH"
                     /protein_id="HDV1988314.1"
                     /translation="MPEEKLQTLSLQVINGSELESGRAARCLFTQQGNVGHAPECHWS
                     VQDRQHSIPAQAFTIILHDGTFCLRPQTVQLWLNQAKVTATSDLIQLRQGDEIQIGRL
                     MMRVHLNRGDIPHYDEEMATPETIVTNRDMLTDTLLSTEGAPHYPGMTHRHQLADTVV
                     NGFSADPLQALQSESLITTGDPLSGIAAVRPSAPLSDPASNGGINSPFMDLPPIYASP
                     GDRNDDVSAAEMAQRHLAVTPLLRGLGGSLTVSNSDDADDFLEEAGRTLQAAIKGLLD
                     LQQQRNSLSDKHLRPLEDNPLRLNMDYATALDVMFAEGKSPVHLAAPAAVSESLRNVR
                     HHEEANRAAIVESLRVLLDAFSPKNLLRRFVQYRRSHELRQPLDDAGAWQMYSHYYEE
                     LASDRQQGFEMLFNEVYAQVYDRVLREKQREPEA"
     gene            7123..7647
                     /gene="tssJ"
                     /locus_tag="RHX21_003163"
     CDS             7123..7647
                     /gene="tssJ"
                     /locus_tag="RHX21_003163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system lipoprotein TssJ"
                     /protein_id="HDV1988315.1"
                     /translation="MNRKAFLACVLMCVILTGCETAKKISEVIKNPDIQVGSLKEQPS
                     EITVTLLTEPDTNTNAEGESAAVDVQLVYLTDDSKLLAADYDQIASTPLPDVLGKNYI
                     DHQDFNLLPDTIKTLPPVKLDEKTQFIGVVAYFSDDQATEWKQIETVEGTGHHYRLLV
                     HVRQSSIEMKKEDE"
     gene            7650..8981
                     /gene="tssK"
                     /locus_tag="RHX21_003164"
     CDS             7650..8981
                     /gene="tssK"
                     /locus_tag="RHX21_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssK"
                     /protein_id="HDV1988316.1"
                     /translation="MATTRNKVMWQEGMLMRPHHFQQQQRYNDYLDNQRFRAMNDLSW
                     GFTELTLNNELLAQGKIMIDSASGTLPDGTVFSIPDQDALPDPLHPQHFPDERSRNIY
                     LALPVASDVRNEISDGRRIGRYRLNYADVRDLHSEEGDARTLTLGQLTPRIMSGAEDM
                     SAYITLPLCRISDRHADGSLTLDDDFIPSCQNIQVSKKLRVYLKEVQGAIGGRASDLA
                     NRIGSPAQSGIADVAEFMMLQLLNRNQTRFTHRARRSQLHPEDFYLDLAGLLGELMTF
                     TELSRLPCPLDVYDHHDLTKTFKTLLPEVKRALHTVLSPRAVNLPLHLRDGIWQADIH
                     DTELLQSATFVLAVAANMPVDQIQRQFIQQSKISSPEKIRNMVSVQIPGIPLRALMVA
                     PRQLPYHSGFSYFELDKSGQAWTEMAAAGAVALHVSGSFPDLNMQLWAIRG"
     gene            8986..9747
                     /gene="icmH"
                     /locus_tag="RHX21_003165"
     CDS             8986..9747
                     /gene="icmH"
                     /locus_tag="RHX21_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IVB secretion system protein IcmH/DotU"
                     /protein_id="HDV1988317.1"
                     /translation="MDEGSLSLPPFTGYDEKSLRDYHLALRGNSLNPMIDAATPLLGM
                     VMRLSTMNSQTMPEHLFAQVVTDVQAVEQLLQEQGYEPGVIISFRYILCTFIDEAALG
                     NGWSNKNEWIKQSLLVHFHNEAWGGEKVFILLERLIREPKRYQDLLEFLWLCFSLGFR
                     GRYKVAAQEQGEFEQIYRRLYHVLHKLRGNAPFPLLHQDKKTQGGRYQLISRLTIKHI
                     FCGGVVVLALFYLFYLLRLDSQTQDILYQLNKLLR"
     gene            9756..12515
                     /gene="tssH"
                     /locus_tag="RHX21_003166"
     CDS             9756..12515
                     /gene="tssH"
                     /locus_tag="RHX21_003166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system ATPase TssH"
                     /protein_id="HDV1988318.1"
                     /translation="MIQIDLPTLVKRLNLFSRQALEMAASECMSQQAAEITVSHVLIQ
                     MLAMPRSDLRVITRQGDIGMEELRQALTVENYTTARSADSYPAFSPMLVEWLKEGWLL
                     ASAEMQHSELRGGVLLLALLHSPLRYIPPAAAQLLTGINRDRLQQDFVQWTQESAESV
                     VPDADCKGAGALTDVADSLLARYAKNMTEDARNDRLDPVLCRDHEIDLMIDILCRRRK
                     NNPVVVGEAGVGKSALIEGLALRIVAGQVPDKLKNTDIMTLDLGALQAGASVKGEFEK
                     RFKGLMAEVISSPVPVILFIDEAHTLIGAGNQQGGLDISNLLKPALARGELKTIAATT
                     WSEYKKYFEKDAALSRRFQLVKVSEPNAAEATIILRGLSAVYEQSHGVLIDDDALQAA
                     ATLSERYLSGRQLPDKAIDVLDTACARVAINLSSPPKQISALTTLSHQQEAEIRQLER
                     ELRIGLRTNTSRMTEVLVQYDETLTALDELEAAWHQQQTLVQEIIALRQQLLGMAEDD
                     AASLPHVDAVEDTPPESEQDNTGAEPADEAGSEQPEETAETVSPVQRLAHLTAELDAL
                     HNDRLLVSPHVDKKQIAAVIAEWTGVPLNRLSQNEMSVITDLPKWLGDTIKGQDLAIA
                     SLHKHLLTARADLRRPGRPLGAFLLAGPSGVGKTETVLQLAELLYGGRQYLTTINMSE
                     FQEKHTVSRLIGSPPGYVGYGEGGVLTEAIRQKPYSVVLLDEVEKAHPDVLNLFYQAF
                     DKGEMADGEGRLIDCKNIVFFLTSNLGYQVIVEHADDPETMQEVLYPVLADFFKPALL
                     ARMEVVPYLPLSKETLATIIAGKLARLDNVLRSRFGAEVIIEPEVTDEIMSRVTRAEN
                     GARMLESVIDGNMLPPLSLLLLQKMAANTAVARIRLSAVDGAFTADVEDAQNDESVTK
                     DETVL"
     gene            12512..13255
                     /gene="tagO"
                     /locus_tag="RHX21_003167"
     CDS             12512..13255
                     /gene="tagO"
                     /locus_tag="RHX21_003167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system-associated protein
                     TagO"
                     /protein_id="HDV1988319.1"
                     /translation="MSRLRVFRQTGWFIAGLMTGLPATAAPAEASSMAGVAVAVATTT
                     PPDATATLQAMQSCRRESAALERLDCYDRLLAPLSPSGFDGALVKAGFVGEAWTRATE
                     QEKHRQGNTTELLVTQVPGERPTVVITTPAIGHVPPRPVLMFSCVDNITRMQVALMHP
                     LDVHDIAVTLNADNRALRSHWFVRENGTLLESSRGLSGIDEIKQLFGAKTLTVDTGAD
                     NAAGKLTFNIDGLARAIAPLRDACHWAGE"
     gene            13260..14672
                     /gene="tssA"
                     /locus_tag="RHX21_003168"
     CDS             13260..14672
                     /gene="tssA"
                     /locus_tag="RHX21_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system protein TssA"
                     /protein_id="HDV1988320.1"
                     /translation="MAMDLRDPNVWISHLLENLPEEKLASALKDDNPNWEYIDGEIVK
                     LGSLAHSQLDIPELQRRGLVILASESKDFRLLAHLLRTLQHAGDPHLALRLLALYVEH
                     YWAVAAPQNMAHKKRFASQVIKRFETGIEVFSQNAATAQRDALSGELAKLAQCWQSHN
                     APELAQATDDLFALYQRAFNRAAPAPVPTPAASGSSPQTTATSESGVTQPSAPAPQIV
                     IDSHDDKAWRDTLLKVAAILCERQPDSPQGYRLRRHALWQNITSTPQAESDGRTPLAA
                     VSADMVADYHAQLGSADMALWQQVEKSVLLAPYWLDGHCLSAQTALRLGYKQVADAIR
                     DEVIRFLERLPQLTGLLFNDHTPFISEQTKQWLAASPDAKVAPVAQIGEESKAARACF
                     AEQGLEAALRYLDMLPEGDPRDQFHRQYLAAQLTEEAGLVQLAQQQYRMLFRMGLQMM
                     VADWEPSLLEQLEQKFTAEQ"
     gene            14781..18215
                     /gene="tssM"
                     /locus_tag="RHX21_003169"
     CDS             14781..18215
                     /gene="tssM"
                     /locus_tag="RHX21_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308245.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system membrane subunit TssM"
                     /protein_id="HDV1988321.1"
                     /translation="MLILAWIFLLVWIWWKGPTWTLYEEQWLKPLANRWLATAAWGII
                     ALMWLTVRVMKRLQQLEKMQKQQREEAVDPLSVELNAQQRYLDRWLLRLQRHLDNRRF
                     LWQLPWYMVIGPAGSGKTTLLREGFPSDIIYAPEGARGAEQRLYLTPHVGKQAVIFDI
                     DGTLCAPADADILHRRLWEHALGWLKEKRARQPLNGIILTLDLPDLLTADKRRREHLL
                     QALRSRLQDIRQHLHCQLPVYVVLTRLDLLQGFAALFQSLNRQDRDAILGVTFTRRAH
                     ENDDWRTELNAFWQTWVDRMNLALPDLMVAQTHTRASLFSFSRQMQGSREPLVSLLEG
                     LLDGENMNVMLRGVYLTSSLQRGQMDDIFTQSAARQYRLGNNPLASWPLVDTAPYFTR
                     SLFPQALLAEPNLATESRAWLIRSRRRLTVFSATGGVAALLLITGWHHYYNGNYQSGI
                     TVLKQAKAFMDVPPPQGEDDFGNLQLPLLNPVRDATLAYGDWGDRSRLADMGLYQGRR
                     IGPYVEQTYLQLLEQRYLPSLFNGLVKALNAAPPESEEKLAVLRVMRMLEDKSGRNNQ
                     VVKQYMAKRWSEKFHGQRDIQAQLMSHLDYALAHTDWHAERQAGDGDAISRWTPYDKP
                     VVSAQKELSKLPVYQRVYQSLKTRALGVLPADLNLRDQVGPTFDQVFTSADDNKLVVP
                     QFLTRYGLQSYFVKQRDELVELTAMDSWVLNLTRSVKYSDADRAEIQRQLTEQYISDY
                     TATWRAGMDNLNIRNFESIGQLTGALEQVISGDQPLQRALTVLRDNTQPGVFSEKLSA
                     KEREEALAEPDYQLLTRLGHEFAPENSTLAVQKDKESTMQAVYQQLTELHRYLLAIQN
                     APVPGKSALKAVQLRLDQNSSDPIFATRQMAKTLPAPLNRWVGRLTDQAWHVVMVEAV
                     HYMEVDWRDSVVKPFNEQLANNYPFNPRSAQDASLDAFERFFKPDGILDTFYQQNLKL
                     FIDNDLSLEDGDNNVIIREDIIAQLETAQKIRDIFFSKQNGLGTSFAVETVSLSGNKR
                     RSVLNLDGQLVDYSQGRNYTAHLVWPNNMREGNESKLTLIGTSGNAPRSISFSGPWAQ
                     FRLFGAGQLTGVQDGNFTVRFSVDGGAMTYRVHTDTEDNPFSGGLFSQFGLSDTLY"
     gene            18226..>19554
                     /locus_tag="RHX21_003170"
     CDS             18226..>19554
                     /locus_tag="RHX21_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system ImpA family N-terminal
                     domain-containing protein"
                     /protein_id="HDV1988322.1"
                     /translation="MNSNVLTQTIVTGSDPRGLPEFSAIREEINKASHPSQPELNWKL
                     VESLALAIFKANGVDLHTATYYTLARTRTQGLAGFCEGAELLAAMVSHDWDKFWPQGG
                     PARTEMLDWFNSRTGNILRQQISFAESDLPLIYRTERALQLICDKLQQVELKRVPRVE
                     NLLYFMQNTRKRLEPQLKSNTENAAQTTVRTLIYAPETQASSTPEAVVPPLPGLPEMK
                     VEVRSLTENPPQASVIKQGSTVRGFIAGIACSVAVASALWWWQVYPVQQQLLQVNDTA
                     QGAATVWMASPELENYERRLQQLLDTSPVQPLETGMQMMRVADSRWPESLQQQQASTQ
                     WNEALKTRAQSSPQLRGWLQTRQDLHAFADLVMQREKEGLTLSYIKNVIWQAERGLGQ
                     ETPVESLLTQYQDARAQKQNTDALEKQINERLEGVLSRWLLLKNNVMPEAA"
BASE COUNT         4522 a         5428 c         5466 g         4138 t
ORIGIN      
        1 aacaggttca tacaatctat ttaacgcttg cagaataccc ctctttacga tcgataaaaa
       61 gtccttttct tatttatttt gaagcgtaaa atgcggggtg atgaaggagt ggtgatttta
      121 ttttcaccgc catcaaggcg gcatttccga tattttttgc ggtacgaata tgccgtgttc
      181 atggcctgta cgagataaca tgacggatca cttttatgag caaaaaattt gaaggcagcg
      241 tcgcgcctcg cgagcgtatt aatatatcgt atgtcccaaa aacagatggc cagacggctg
      301 aagtggaact tccgcttaac atgctcgttg tcggcgatac cggaaatacg caggaaacat
      361 cctcactgga tgaacgtcag gcagtttccg ttaacaagca caatttcggt gcagtgatgg
      421 ctgaagcagc cattggcctc aattttaccg tccccgccac gctgaaggga agcacaacgg
      481 acgatgagct gaatgtggcg ctgaatatca agtcactgga tgatttttca ccagatagcg
      541 tggcccggca ggttccggaa gtgaataaat tgctggaact gcgtgaagca ctgactgcac
      601 tgaaggggcc gatgggtaac cttccggcat tccgtaccca gctccaggca ttgctggaaa
      661 atgaagagtc ccgcgagcag ttgctcaaag aaatcggcca ggtgagcaat aaataaccac
      721 cactatttca ttaaacaggg ttatccaggc atgacggcac acaaaaatat ctccgggaca
      781 taccacctct ctgttgcaga cattctgcag gtggtttacc aggtatgttt cagcccgtcc
      841 gttgaaatca accaggatgg tgtggctgcg ctgattacaa cactggatcg ccgtatcagt
      901 gatctattgg atgagattat ccatttttgt gagtttcagc agagcgcgtc gcactggcag
      961 cgcgtacttc actgacggcg aaaagccggt ttcagaaaca cagctaaaac agaaggattt
     1021 tcagtatgtc tttacaggaa gaggaactcg tatccagtca tgccgggcag cctgagcagg
     1081 catcgtcgct gcttgatcaa atcatggcac agacccgtat tcagcccggt tcggaaggtt
     1141 atgacgttgc ccgccagggt gtgacagcct ttattgccag catcctgcaa tccactgcat
     1201 ctgccgaacc ggtcaataaa ctggccgtgg acagcatgat tgcagatatt gatgaacgca
     1261 tcagccgcca gatggatgtc atcatccatg cgcctgcctt tcagcaggtc gagtcgttct
     1321 ggcgctcact gaaaaccatg gtggatcgcg ttgatttccg tgaaaacatc aaggtcaacg
     1381 tgcttcatgt catcaagcag gaacttctgg aagactttga gtttgcgcca gaaattattc
     1441 agtccggatt ttataagcac gtttattcgt ccggtttcgg acagtttggc ggtgaaccca
     1501 tcgctgccgt gctgggcgct tatgagttca aaaataccgc gcctgacatg aaactgctgc
     1561 aatacgtcag tgccgtgggc gcaatggcgc acgcaccgtt cctgtcctcc gtttccccgg
     1621 agtttatggg gctgaactcg tggaccgaac tgcctaatat caaagatctt tatgccatct
     1681 ttgaaggtcc ggcctacacc aaatggcgcg ccctgcgtga ctcggaagat tcgcgctatt
     1741 tagggcttac ggcaccccgc ttcctgcttc gccagcccta ttcaccaaca gataaccctg
     1801 ttaagaactt taactattac gaagatgtca gccagaacca cgaagattat ctgtggggta
     1861 atacggcctg gatgctggca tgcaatatcg cagacagttt tgccaaatac cgctggtgtc
     1921 caaacattat cggtccgcaa agcggcggcg cagtgaaaga tctgccggtg catctgttcg
     1981 aaacgatggg gcagattcag gccaaaatcc caaccgaggt gctggtcacc gatcgccgcg
     2041 aatttgaact ggctgaagag ggttttatca cccttaccat gcgtaaagac tctgataatg
     2101 cagccttttt ctctgcaaac tcggtacaaa aaccgaagca ctttccggga aaagatgcag
     2161 aaaccaacta taagctgggt acgcagcttc cttatctctt catcatcaat cggttagcgc
     2221 actacatcaa ggtgttgcag cgtgaacaac tggggtcatg gaaagaaagg agcgacttag
     2281 aaagagagct taatacctgg atccgtcagt atgttgccga ccaggaaaac ccgcctgcag
     2341 acgtgcgcag ccgcaaacct ctgcgcgctg ccaaagttga ggttatggat gtagaaggcg
     2401 aacccggctg gtaccaggtt gcgctaagcg tgagacctca ttttaaattt atgggggcaa
     2461 attttgagct ttccctggtt ggccggttag acagggagta acacaccatg ataccggatc
     2521 gggaaagaac cacaggttct ctttttgagc gtatggaagc ctcttcggcc agaaaccggc
     2581 agggaggcag tattcattcg ctcaggcaat ccattcgcca gaacctacga aacattctta
     2641 atacccggtc cggtagttgc cggggtgcgc ctgagctggg tattgatgaa ccggaagggg
     2701 ctgaaaactt ccgcgaatcc atgagtcggg ccatcgagca atgtatagaa cgctatgaac
     2761 cccggatctc acacgctgaa gtgcaggcag tggtttcatc cgcctccagc ccgctggata
     2821 tgacgtttca tattacagcc tgggtgacat ttaacgaaac gcatgaggtg cttgaatttg
     2881 atatggcacc gaatggcagc cagcattacc gggtggactg acaaatggaa tttgaagaac
     2941 gctatttccg ggaagaactc gattacctgc gccagcttag caagctgctg gcaacggaaa
     3001 aaccccatct ggcccgcttc ctggccgaaa aagatgcgga tccggatatt gaacgcctgc
     3061 tggaaggggt ggcttttctt accggcaatc tccgccagaa aattgaggat gaattcccag
     3121 aactgacgca cgggcttatt aagatgctat ggcctaatta cctgcgtccg gttccggcaa
     3181 tgacccttat tgaatatacg ccggatatgg ataagtcttc tgtaccggtg ttaatccccc
     3241 gtaatgagca gtttacaacc aacgccgggg aaatcagagt tgatgaagtg ctgccctctg
     3301 atgctaaaaa ggaggagccg cctccctgta ccttcaccct ctgccgggat atctggctgc
     3361 tgcccgttcg cctggagcag attgaaaacc gcagtacgac ccgtaatggt gttatcaaca
     3421 tcaccttttc ggtcgcaccg ggaacggact tccgcacgct ggatctgaac aaacttcgct
     3481 tctggctcgg caatgacgac aactataccc gtgaccagct ttatttatgg ttctgcgaat
     3541 acttgcaggg tgccgacctg actgtgggtg aacagcatat tcgcctgcct gagtttatgc
     3601 taaaagctgt cggttttgag ccgcaggatg ccatgctgcc ctggccgaaa aacgtccaca
     3661 gcggctaccg gatccttcag gagtatttct gttaccccga tgcgtttctc ttttttgatc
     3721 tttgtggttg tccggctttg cctgacggat tgcaggcgga attctttacc ctgcaactgc
     3781 gtttttcgcg ccctttgccc gtggacatcc ggctgcgccg cgattccctg cgcctgtatt
     3841 gcgcacctgc cattaattta tttatccacc atgcagaagc catcacgctg gacaaccggc
     3901 gggcagacta tccgctggtt cccagccgcc attacccaca acattacgat gtattttccg
     3961 ttaacagtgt ggtgagccag gtccaggata tgttcaggaa aaaagatctg gggcgtcctg
     4021 tttcgacgca ggccgcgcgc cagtggccag cctttgaaag tttcagccat cagatggaat
     4081 acagccggaa gcgggaagtg gtgtactggc atcaccggac caaaacatcc ctgttccatc
     4141 gcggctttga tcataccctt gcctttatac atgctgatgg cagttatccg tcagacgaat
     4201 ctctgctcag taatgaagtg gtttcggtat cgctgacctg taccaaccgt gagcttccgt
     4261 cacaaattcg ttccggcgat atcaccggca caaccggtaa aaatgcggct gttgcttcat
     4321 ttcgcaacat tacccgcccg acgcaaccac tctggccggt cattgatggc agcctgcact
     4381 ggtccctact ctccgccatg aacctgaatt atctgtcatt actggatacg gacgcgctga
     4441 agcaggtcat cgccaacttt gatcgccacg caatccatca tccgcagacg gcacggctgt
     4501 cacaacaaaa gctggatgcc attgagcgtc tggagacccg ccccgttgat cgcctgttta
     4561 cgggtattcc cgtccgggga ctggcctcca cgctgtatct gcacccggag ccgtttgtct
     4621 gtgaagggga aatgtatctg ctcggtacgg tgctttcgca ttttctgtcg ctgtacgcca
     4681 gcgttaactc attccacatg ctgaccgttg tgaacacaga aagccaggag acatggaaat
     4741 ggacggaaag aatcgggcag catcctctta tctgagtccg ggaaatcccc cggcagataa
     4801 agagcagaat gatccgctgg cacaggtttt ccataatgcc tgctcttaca atttttttgc
     4861 gatggcggag ctgttgcacc gcctggcaaa gggtgaaaag gggacgccag aattatccct
     4921 gcgtgacgat ccggcacagg aaaccctgcg tttcagcgcc gatgccagcc ttgccttccc
     4981 gtgcagtgat atcagtgcgc tgaaacggga tacgtcaggg gcattcagga tgaccaccac
     5041 ctttatgggg ttacagggga gccagtcgcc tctccccggt tattacctcg atcacctggc
     5101 ctggaaagcg gtacatgaac aaagtccggt aggtgatttt ctggatatgt tcagccaccg
     5161 cctgacccag tttgtctggc atatctggcg taagtaccgc tatcacatca gttttcgtaa
     5221 cggcggtgtg gatgcgttct cgcagcgcat gtactccctt gtcgggctgg gccaccgcca
     5281 gcttcgcgat aagctggcga ttaatcacag caaaatgctg gcgtattccg ggatcctggc
     5341 aaacccgggg cgatccccgg aaattatctg tggcctggtg tcccactgct ttgatttgtc
     5401 agaagtgacg ctgcaaaact ggcagcgtcg caaggtggat attgaaccgg atcagcaaaa
     5461 tagtctgggg agctattcac ttaaaaatgg cgaaaaactg gcgggaagat cggtactggg
     5521 caactttgtt ctgggtacac gggtgcccga tctcagcgga aaattccagc tcagtattac
     5581 cagcctgacc cgaaaacagt tcctctcttt tctgccgtcc ggcgaaaact tcctgccact
     5641 gacgatgttt gtgtccttca tcctgcgcga tcagcttgcc tgggacttac atctggggct
     5701 ggcgccggag caggtgggcg caatgcgcct gggcgataac aaaagtgcgc tgctgggctg
     5761 gaccagcttc ctcggcacac cggaagaacg accctcagtc accatcaggg tacggtcgta
     5821 aattatgata atcacggagc agaatatgcc ggaagagaaa ctacagacgc tttcattgca
     5881 ggtcattaac ggcagtgagc tggaaagcgg gcgggcggcg cgctgtctgt tcacacagca
     5941 gggaaatgtc ggccatgccc ccgaatgcca ctggtcggta caggatcgtc agcatagcat
     6001 tccggcccag gcttttacca ttatcctgca cgatggcaca ttttgtctgc gcccgcagac
     6061 ggtacaactg tggctgaacc aggcaaaagt cacagcaaca tcagacctga tacagctgcg
     6121 ccagggcgat gagatccaga tcgggcgact gatgatgagg gttcatctga accggggaga
     6181 tatcccccat tacgatgagg aaatggcgac gcccgaaacc atcgtcacca atcgcgatat
     6241 gctcacggat accctgctgt caacggaggg tgcgccacat tatccgggaa tgactcaccg
     6301 gcaccagctt gcagacaccg tggtaaacgg tttttctgcc gatccactcc aggcacttca
     6361 gtccgaaagc ctgattacca caggcgatcc gctttcaggc attgcggctg tccggccctc
     6421 ggcaccgctg tccgatcccg caagtaatgg cgggatcaat tcgccgttta tggatctgcc
     6481 gcccatttat gccagccccg gcgatcgtaa tgatgacgtc tctgcggcag aaatggcgca
     6541 acgccacctt gcggtcaccc ccttactgcg cggtctcggc ggctcgctta ccgtgagcaa
     6601 ttccgacgat gcggatgatt ttctggagga ggccggacga accttacagg ccgcaataaa
     6661 aggtctgctc gatttgcagc agcagcgtaa cagcctctca gacaaacatt tgcgcccgct
     6721 ggaagataac ccgctgcgcc tgaacatgga ttacgccacc gcgctcgacg tgatgtttgc
     6781 cgaaggcaaa agcccggtac atctggcggc ccccgccgcc gtcagtgaaa gcctgcgcaa
     6841 tgtccgccac cacgaagaag ctaaccgggc ggcgattgtg gagtcacttc gtgtcctgct
     6901 ggacgccttc tcacctaaaa atctgctgcg ccgctttgtg cagtaccgcc gtagccatga
     6961 actgcgccag ccgctggatg atgccggagc atggcaaatg tacagccatt attacgaaga
     7021 actggcctcc gatcgccagc aggggtttga gatgctgttt aacgaggtct acgcccaggt
     7081 ctatgaccgg gtgcttcgtg aaaaacagcg ggagccggaa gcatgaacag gaaggcgttt
     7141 ctggcctgcg tgctgatgtg cgtcatatta accggctgcg aaacggcgaa aaaaatcagt
     7201 gaggtgatca aaaacccgga tatccaggtc gggagcctga aggagcaacc ttcggaaata
     7261 accgtcaccc tgctgaccga accggacacc aataccaatg cggaaggtga atcagccgcc
     7321 gtggatgtgc aactggtgta cctgactgac gactcaaaat tgctggcagc cgactatgac
     7381 cagatagcca gtacgccgct accggatgtg ctgggtaaaa actatatcga ccaccaggat
     7441 ttcaacctgt tgccggacac catcaaaacc ctgccgccgg taaagctgga tgagaaaacg
     7501 cagtttattg gtgtcgtggc ctatttctcc gatgaccagg ccactgaatg gaaacaaatc
     7561 gagacggtgg aaggaaccgg ccaccattac cgcctgctgg tgcatgtacg tcaaagcagc
     7621 atcgaaatga aaaaagagga tgaataatta tggcaaccac ccgcaacaag gtgatgtggc
     7681 aggaagggat gctgatgcgc ccacaccatt tccagcaaca gcagcgttac aacgactacc
     7741 tggataacca gcgtttccgg gccatgaatg atttatcctg gggatttacc gaactcaccc
     7801 tcaacaatga actgctggcg cagggtaaga tcatgattga cagcgcgtca ggcacactgc
     7861 ccgacggcac cgtcttttct atccccgacc aggacgcact gcccgatccg ctgcacccgc
     7921 aacattttcc ggacgagaga agccgcaata tctacctcgc tctgccggtc gccagtgatg
     7981 tgagaaatga aatcagcgac gggcggcgaa tcgggcgtta ccggctgaat tatgccgatg
     8041 tccgggattt gcattcagaa gaaggtgacg cgcgaacact gacgctggga caactgacgc
     8101 cgcgcattat gagcggtgca gaagatatga gcgcctatat tacgctcccg ctttgccgta
     8161 tcagcgatcg ccatgccgac ggctccctga cgctggatga cgattttatc ccctcctgcc
     8221 agaatattca ggtcagtaag aaactgcgtg tttatctcaa agaggtacag ggggccattg
     8281 gcggacgggc aagcgatctg gcaaaccgta ttggctctcc ggcgcagagc ggcatcgcgg
     8341 atgtggcgga atttatgatg ttgcagttgc ttaaccgtaa ccagacccgg tttacccatc
     8401 gcgcccgccg atcccagctc cacccggaag atttctatct tgatcttgcc gggttgctgg
     8461 gtgaactgat gacctttaca gagctgtcgc gcctgccctg cccgcttgat gtgtatgatc
     8521 atcatgacct gaccaaaaca tttaaaacac tgttaccgga agtcaaacga gcgctgcata
     8581 ccgtactgtc ccccagagcc gtcaatctgc cgctgcatct gcgtgacggt atctggcagg
     8641 ccgatatcca tgacacagaa ctgctgcaat ctgccacctt tgtgctggcc gtggcggcaa
     8701 acatgccggt cgatcagatc cagcgccagt ttatccagca gtcgaaaatt tcctcgccgg
     8761 aaaaaatccg caatatggtc agtgtgcaga tcccgggtat tcctctgcgc gcactgatgg
     8821 tggccccccg ccagcttccc taccattccg ggttcagcta tttcgaactc gacaagagcg
     8881 gccaggcctg gacagaaatg gctgccgccg gagccgttgc actgcatgtc tccggcagtt
     8941 tcccggatct gaacatgcaa ctgtgggcga taagagggta agacgatgga tgaggggtca
     9001 ctgtctctgc caccatttac cggatacgac gaaaaaagcc tgcgcgacta ccatctcgcg
     9061 cttcgtggca acagcctgaa tccgatgatc gacgcggcca cgccgctcct cggtatggtg
     9121 atgcgccttt ccactatgaa cagccagacg atgccggagc atctttttgc tcaggtggtg
     9181 acggatgttc aggccgtgga gcaactgctt caggagcagg gctacgaacc gggcgtgatt
     9241 atctcgtttc gctacatcct ctgcacgttt attgatgaag cggcgctcgg taacggctgg
     9301 tcgaacaaga acgagtggat caagcagtca ttgctggtcc atttccacaa cgaagcctgg
     9361 ggtggcgaga aagttttcat cctgctggag cgcctgatcc gtgaacccaa acgttaccag
     9421 gatctgctgg aatttctctg gctctgcttt tctctgggat ttcgcgggcg ctacaaagtg
     9481 gcagcacagg agcaggggga atttgagcag atctaccgcc gcctgtacca cgttctgcat
     9541 aaactgcgcg gcaatgcccc tttcccgctg ttacaccagg ataaaaaaac ccagggcggg
     9601 cgttatcagc tcatcagtcg cctgaccatt aaacatattt tttgtggtgg cgttgtcgtg
     9661 ctggcgttgt tttacctgtt ctatctgttg cggctggaca gccagacgca ggacatcctg
     9721 taccagctaa acaaattact tcgataagga cgtttatgat ccagattgat cttcccacgc
     9781 tggtaaaacg gctgaacctg ttctcccgcc aggcgctgga gatggccgcc tctgaatgta
     9841 tgagccagca ggcagcggaa attaccgtca gccatgtgct tattcagatg ctcgccatgc
     9901 cacgcagtga cctgcgggtt attacccgcc agggtgatat tggcatggaa gaactgcgcc
     9961 aggcgctgac ggtggagaac tacacaaccg cccgttctgc ggacagctac ccggcgtttt
    10021 ccccgatgct ggttgagtgg ctgaaagagg gctggctgct ggcgtcggct gagatgcagc
    10081 acagcgaact gcgcggcggc gtgttgctgc tggccctgct gcattcaccg ctgcgttaca
    10141 taccgcctgc tgccgcccag ctgttgaccg gcattaaccg tgaccgtctg caacaggact
    10201 ttgtgcagtg gacacaggag tcggcggaat cagtcgtgcc ggatgcagac tgtaaaggcg
    10261 caggcgcact gacggacgtc gctgacagcc tgcttgcccg ctacgccaaa aacatgaccg
    10321 aagatgcccg taacgacagg ctcgacccgg tactgtgccg cgaccacgaa atcgacctga
    10381 tgatcgacat tctctgccgt cgccgtaaaa ataacccggt ggtggtgggc gaagcgggtg
    10441 tgggtaaaag cgccctgatt gaagggctgg cgctgcgtat cgtggcaggc caggtgccgg
    10501 acaagctgaa aaacaccgat atcatgaccc ttgacctggg cgcattgcag gccggggcat
    10561 cggtgaaagg tgagtttgag aaacgcttca aagggctgat ggcggaggtc atttcctccc
    10621 cggtgccggt cattctgttt atcgacgaag cgcataccct tattggcgcg ggcaaccagc
    10681 agggtgggct ggatatctcc aacctgctca agccggcgct ggcgcgcggc gagctgaaaa
    10741 ccatcgccgc caccacctgg agcgagtaca aaaaatactt cgaaaaagat gccgccctgt
    10801 cgcgccgatt ccagttggtg aaggtcagcg aacccaacgc tgccgaagcc actattattc
    10861 tgcgtggtct gtcggcggtc tatgaacagt ctcacggtgt gctgattgac gatgacgcct
    10921 tgcaggccgc agcaacactg agcgagcgtt atctctccgg gcgtcagttg ccggacaaag
    10981 ccattgatgt gctggatact gcctgcgccc gcgtggcaat caacctttca tcgccaccaa
    11041 agcaaatctc ggcgctgacc accctgagtc accagcagga ggcggaaatt cgccagcttg
    11101 agcgcgagct tcgcatcggg ctgcgtacca acacctcgcg aatgacggag gtgctggtgc
    11161 agtatgatga aacgctgacg gcgctggatg aactggaggc cgcctggcat cagcaacaga
    11221 cgctggtgca ggagattatc gccctgcgcc agcagttact gggtatggca gaagacgatg
    11281 cggcgtcgtt gccgcacgtg gatgccgtgg aggatacgcc gccagagtca gaacaggata
    11341 ataccggtgc cgaaccggct gatgaagctg gcagcgaaca gccggaagag accgctgaaa
    11401 cagtttcccc ggtacaacgt ctggcacatc tcactgccga actggacgcc ctgcataacg
    11461 accggttgct ggtttccccg cacgtcgata aaaaacagat tgcggcggtg attgccgaat
    11521 ggaccggcgt gccgcttaac cgcctgtcgc agaatgaaat gtcggtcatc accgacctgc
    11581 caaaatggct cggcgacacc atcaaaggcc aggacctggc gattgccagc ctgcacaaac
    11641 acctgctgac cgcacgcgcc gacctgcgcc gtccgggacg cccgctgggc gcgttcctgc
    11701 tggctggccc cagcggcgtg ggtaaaactg aaaccgtcct gcaactggca gagctgctct
    11761 acggcggtcg ccagtacctg accaccatca atatgtccga gttccaggag aaacataccg
    11821 tctcgcgact gattggctcc cctccgggct acgttggcta cggtgaaggc ggcgtactga
    11881 ccgaagcgat tcgccagaaa ccctactcgg tagtactgct cgatgaagtg gaaaaagcgc
    11941 acccggatgt gctcaacctg ttctaccagg cgttcgataa gggcgaaatg gcagacggtg
    12001 aaggccgcct gattgactgc aaaaatatcg tcttcttcct gacgtccaac ctcggctacc
    12061 aggtaatagt cgagcatgcc gatgacccgg aaaccatgca ggaagtactg tatccggtgc
    12121 tggccgactt cttcaaacct gccctgctgg cgcgtatgga agtggtgccg tacctgccgc
    12181 tgtcgaaaga gacgctcgcc accatcattg ccgggaaact ggcccgcctg gataacgtgc
    12241 tgcgcagccg ctttggcgcg gaggtgatta tagaaccgga agtgacggac gaaatcatga
    12301 gccgcgtcac ccgcgcggaa aacggcgcga ggatgctgga atcggtcatc gacggcaata
    12361 tgctgccgcc gctctccctg ctgctgttgc agaaaatggc ggcgaatacg gcggttgccc
    12421 ggattcggtt gtcggcagtg gacggcgcat ttacggcaga cgtggaagat gctcagaacg
    12481 acgagtccgt cacaaaggat gaaacggttt tatgagcagg ttgcgcgttt tccggcagac
    12541 aggatggttt atcgcgggcc tgatgacggg cttacccgcc actgccgcgc ccgcagaagc
    12601 atcgtcaatg gccggtgtgg cggtcgccgt cgccaccacg accccgccgg atgcgacagc
    12661 cacgttacag gccatgcagt cctgtcggcg ggagtccgcg gcgctggagc ggcttgactg
    12721 ctatgaccgc ctgctggcac cgctgtcccc gtcagggttt gacggggcgc tggtcaaagc
    12781 cggttttgtg ggcgaagcct ggacccgcgc cacggaacag gaaaaacacc gccagggcaa
    12841 caccacagag ctgctggtga cgcaggtgcc gggggagcgc ccgacggtgg tgataaccac
    12901 cccggctatc ggtcatgttc cgccacgccc ggtgctgatg ttcagttgcg tggacaatat
    12961 cacccggatg caggtggcgc tgatgcaccc tctggatgtc catgatatcg ccgtcactct
    13021 gaatgccgac aaccgggcat tgcgcagcca ctggtttgtg cgcgagaacg gcaccctgct
    13081 ggagtccagc cgggggttat ccgggattga tgaaattaag caactgttcg gcgcaaaaac
    13141 gctgacggtg gataccggcg cagacaatgc cgccggaaag ctgaccttta acattgacgg
    13201 gctggcaagg gcgattgctc ccctgcgcga tgcctgccac tgggcgggag aataaaaata
    13261 tggcaatgga cttacgcgat ccgaatgtct ggatatcgca cctgctggaa aacctgccgg
    13321 aagagaaact ggcatcggcg ctgaaagatg acaacccgaa ctgggagtat atcgacggcg
    13381 aaatcgtcaa gctgggatcg ctggcccaca gtcaactgga tatcccggaa ctccagcgcc
    13441 gtgggctggt cattctggct tcggagagta aggattttcg tctgctggcg catctgctga
    13501 gaaccctgca acacgccggt gatcctcatc tcgcattgcg cctgctggcg ctgtatgtgg
    13561 agcattactg ggcggtggct gcgccgcaga atatggcgca taaaaaacgc tttgccagcc
    13621 aggtcattaa acgctttgaa acaggtattg aagttttttc acagaacgcc gccacagcgc
    13681 agcgcgatgc gctgtcaggg gaactggcaa aactggcgca atgctggcag tcacataacg
    13741 ccccggaact ggcacaggct actgatgatc tttttgccct gtaccagcgt gcgtttaatc
    13801 gtgcggcacc ggctcctgtc cccactccgg cggcctccgg tagttcacca cagaccaccg
    13861 ccacgtctga aagcggcgtg acgcaaccca gtgctccggc tccccaaatc gtcatcgaca
    13921 gtcacgacga caaagcctgg cgcgacacgc tgttaaaagt ggcggccatt ttatgtgaac
    13981 gccagccgga ttcaccgcag ggctaccgtc tgcgccgcca tgcgctttgg cagaacatca
    14041 ccagtacgcc ccaggcggaa agcgatggcc gtactccact ggctgcggtc tccgccgata
    14101 tggtggcaga ttaccatgct cagctcggta gtgccgatat ggcgctgtgg cagcaggtgg
    14161 agaaaagcgt actgctggct ccttactggc tggatggtca ctgcctttct gcacagacgg
    14221 cgctgcgtct gggttacaaa caggtggcag acgccatccg cgatgaggtc atccgcttcc
    14281 ttgagcgtct gccccagctt accgggctgc tgtttaatga ccacacaccg tttatcagtg
    14341 agcagacgaa acaatggctg gcagcttcgc ccgacgccaa agttgcaccg gttgcgcaaa
    14401 tcggtgagga atcgaaggca gccagagcct gttttgctga gcagggtctg gaggcggcgc
    14461 tgcgatatct ggacatgcta cccgaaggcg atccccgcga tcagtttcac cgccagtacc
    14521 ttgccgcaca gttgacggaa gaggcggggc tggtacagct tgcgcagcag cagtaccgga
    14581 tgttgttcag gatgggattg cagatgatgg tggcagactg ggagccgtcc ctgcttgagc
    14641 agctagaaca aaaattcacg gcagaacaat aaaagagaac aggagttttt gtgttcagat
    14701 taccaacacc ccgactactc agcggactca aatcagccct gcgaccggcg atgccccggt
    14761 ttaaagtctc tgctttctgg ctgctgatac tggcgtggat ttttctgctg gtgtggatct
    14821 ggtggaaagg cccgacgtgg acgctgtatg aagaacagtg gctcaaacca ctggcgaacc
    14881 gctggctggc aacggcggcg tgggggatta ttgccctgat gtggcttacc gtccgggtga
    14941 tgaagcgcct gcaacagctt gaaaaaatgc aaaagcaaca gcgcgaggaa gccgttgatc
    15001 cgctcagcgt ggaactgaac gcccagcagc gttatcttga ccgctggctg ctgcgcctgc
    15061 aacgccatct cgacaaccgc cgtttcctgt ggcagttgcc gtggtatatg gtcatcggcc
    15121 cggcgggcag tggcaaaacg acactgctgc gcgaggggtt tccgtccgac attatttatg
    15181 ccccggaggg cgcacgcggc gcagaacaac gcctgtacct cacgccccat gtcggtaaac
    15241 aggcggtgat ctttgatatc gacggcacac tctgcgctcc cgctgatgcg gatatcctgc
    15301 atcgccgtct gtgggaacat gccctcggct ggctgaaaga aaagcgcgcg cgccagccgc
    15361 tgaatgggat tattctgaca ctcgatttac ccgatctgct taccgcagac aaacgccgcc
    15421 gcgagcatct gttacaggcg ctgcgcagcc gcttgcagga tatacgccag catcttcact
    15481 gccagttacc ggtttacgtg gtacttaccc ggcttgattt attgcagggt tttgccgccc
    15541 tgtttcagtc cctgaacaga caggatcgcg atgcgattct gggcgtcacg ttcacccgcc
    15601 gtgcccatga aaatgatgac tggcgaacag agttgaatgc tttctggcag acatgggtgg
    15661 atcgaatgaa tctggcgttg ccggatctga tggtcgctca gactcacacc cgcgcgtctt
    15721 tattcagttt ttcccgccag atgcagggaa gccgtgaacc gctggtgtca ctgcttgagg
    15781 gtctgcttga tggcgaaaat atgaacgtga tgctgcgtgg tgtctatctc acctcttcgc
    15841 ttcagcgtgg acagatggat gatatattca cccagtctgc cgcccgccag taccggctgg
    15901 gcaataaccc tctggcgtcc tggcccctgg tggacaccgc gccttatttc acccgcagcc
    15961 tgttcccgca ggcattactc gcagagccta atctggcaac agagagccgc gcctggctga
    16021 tacgttcccg tcgccgcctg acggttttct ctgccacagg cggcgtggca gcactgctgc
    16081 tcatcaccgg ctggcatcac tattacaacg gtaactatca gtctggcatc accgtgctta
    16141 agcaggccaa agcctttatg gacgtgccgc ctccgcaggg ggaagatgac tttggcaacc
    16201 tgcaactgcc gctcctgaac ccggtacgcg atgccacact ggcctatggc gactggggcg
    16261 accgcagccg tctggccgat atgggactgt accagggacg acgtatcggg ccttatgtgg
    16321 aacagaccta tctgcaactg ctggagcaac gttacctgcc ctcgctgttt aacgggctgg
    16381 tcaaagcgct gaacgccgcg ccgccggaga gtgaagaaaa actcgcggtg ctgcgcgtga
    16441 tgcgaatgct ggaggacaaa agcggacgta acaatcaggt ggtgaagcag tatatggcaa
    16501 aacgctggag cgaaaagttc cacggtcagc gcgatatcca ggcacaactg atgtcccatc
    16561 ttgactacgc gctggctcat actgactggc acgcagagcg tcaggcgggc gacggtgacg
    16621 ccatcagccg ctggacgcca tatgacaagc ccgtggtatc agcacagaaa gaactgagca
    16681 aactgcctgt ctaccagcgg gtttaccaga gcctgaaaac gcgggcgctg ggcgttcttc
    16741 ctgccgacct caatctgcgt gaccaggtag ggccaacctt tgaccaggtg tttacatctg
    16801 ccgatgacaa caaactggtt gttccacagt ttcttacccg ttacggcctg caaagctatt
    16861 ttgtaaaaca gcgcgatgaa ctggttgaac tgacggcgat ggattcctgg gtacttaacc
    16921 ttacccgcag cgtgaaatac agtgacgccg accgcgcgga aatccagcgc cagttgaccg
    16981 agcagtatat cagcgactac accgccacct ggcgggccgg gatggacaat ctgaatatcc
    17041 gcaattttga gtccatcgga caactgaccg gggcgctgga gcaggttatc agcggcgacc
    17101 agcctttgca gcgggcgctg accgtgctgc gtgacaacac acagccaggc gtcttttctg
    17161 aaaaactctc tgccaaagaa cgggaggaag ccctggcaga gccggattac cagttactca
    17221 cccgcctcgg gcatgaattc gccccggaaa acagtaccct ggcagtacag aaagacaaag
    17281 aaagcacgat gcaggccgtg tatcagcaac tcaccgagtt gcaccgctac ctgctggcaa
    17341 tccagaacgc gcctgtacca gggaaatcgg cgctgaaagc cgtgcagtta cggcttgatc
    17401 agaacagcag cgatccgata ttcgccaccc gccagatggc aaaaacgctg cctgctccgc
    17461 tcaaccgctg ggttggcaga ctgactgacc aggcctggca tgtggtgatg gtggaggctg
    17521 ttcattatat ggaagtggac tggcgcgaca gcgtggtgaa accgtttaac gagcaactgg
    17581 caaataacta tccgtttaat ccgcgttctg cacaggatgc ctcactggat gccttcgaac
    17641 gcttctttaa accggatggc atactggata ccttctacca gcagaacctg aagctgttta
    17701 tcgataatga cctgagtctg gaggatggcg ataacaacgt cattattcgc gaagatatta
    17761 ttgcgcaact ggaaactgcg cagaaaatcc gtgacatctt cttcagcaaa cagaacggtc
    17821 tgggaacatc ctttgccgtg gaaacggtat cgctttcagg caataaacgc cgcagtgtac
    17881 tgaaccttga cggtcagtta gtcgattaca gccagggccg taactatacc gcccatctgg
    17941 tctggcctaa caacatgcgc gaaggcaacg aaagtaagct gacgctcatc ggcaccagcg
    18001 gcaacgcgcc gcgcagtatc agcttcagcg ggccgtgggc gcagttccgc ctgttcgggg
    18061 ccggacaact gaccggagta caggatggca actttaccgt gcgctttagc gtggacggtg
    18121 gcgcgatgac ctaccgtgtg cataccgaca cggaagataa cccgttcagc ggtgggttgt
    18181 tcagccagtt tggtctgtca gacacactgt actgaggagg cagggatgaa tagtaacgta
    18241 ctgacacaaa ctatcgttac cggcagtgac ccgcgcgggc tgccggaatt cagcgccatc
    18301 cgcgaggaaa taaacaaagc cagccacccg tcacagcctg agctgaactg gaaactggtg
    18361 gagtcgctgg cactggcgat ttttaaagcc aacggtgtgg atttacacac cgccacctac
    18421 tatacgcttg cccggacacg gacacaggga ctggcgggat tctgcgaagg tgcggaactg
    18481 ctggcggcaa tggtaagcca cgactgggat aagttctggc cgcagggcgg cccggcgcgt
    18541 actgaaatgc tggactggtt taactcccga accggcaata ttctgcgtca gcaaatctcc
    18601 tttgcggaat ccgacctacc actgatctac cgcacagagc gggcattgca gcttatctgc
    18661 gataagctcc agcaggtgga actgaagcgc gttccgcgcg tggagaatct gctctatttt
    18721 atgcagaaca cgcgtaaacg gcttgaaccc cagctgaaga gtaacactga gaacgccgca
    18781 cagaccacgg tcagaacgct gatttatgcc ccggaaacac aggcatcttc cacaccagaa
    18841 gcggtagtgc ctcccctgcc cggcctgcct gagatgaaag tggaagtgcg cagtctgaca
    18901 gagaatcccc cacaggccag tgtgataaag caaggcagta cggtaagagg gtttatcgca
    18961 gggatcgcct gttcagtggc tgtcgcctca gcattgtggt ggtggcaggt ctatccggta
    19021 cagcagcaac tgttacaggt taacgacacc gctcagggcg cagcaacggt gtggatggcc
    19081 tcacctgaac tcgaaaacta tgagcgcagg ctgcaacaac ttcttgatac ctccccggta
    19141 cagccgctgg aaaccgggat gcagatgatg cgtgttgccg acagtcgctg gccggaaagc
    19201 ctgcaacagc aacaggcctc gacacaatgg aatgaggcac tcaaaacccg cgcacagagt
    19261 agcccgcagt tgcgtggctg gttgcagacc cgccaggact tacatgcttt tgcagatcta
    19321 gtgatgcagc gcgagaaaga gggactaacc ctttcctata tcaaaaatgt catctggcag
    19381 gcggagcggg gactggggca ggaaacaccc gttgagtctc tgttgacgca gtaccaggat
    19441 gcccgtgcgc agaagcagaa tacagatgcg ctggaaaaac aaattaatga gcgactcgaa
    19501 ggcgtgttaa gccgctggct gctgctgaag aataacgtca tgccagaggc ggca
//
LOCUS       DAPGUL010000083        18893 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.084, whole genome shotgun sequence.
ACCESSION   DAPGUL010000083 DAPGUL010000000
VERSION     DAPGUL010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18893)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18893)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18893
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.084"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            26..589
                     /locus_tag="RHX21_003171"
     CDS             26..589
                     /locus_tag="RHX21_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDV1988323.1"
                     /translation="MSKFVKTAIAATMVMGAFASTSTIAAGNNGTARFYGTIEDSPCS
                     IVPDDHKLEVDMGDIGSGILKNNGTSTPKAFQIHLQDCVFDTQTTMTTTFTGNASSTN
                     SGNYYTIYNTDTGAAFNNVSLAIGDAQGTSYKSGAGIEQKIVNDTATNKGKAKQTLDF
                     KAWLVGAADAPDLGNFEANTTFQITYL"
     gene            671..3310
                     /locus_tag="RHX21_003172"
     CDS             671..3310
                     /locus_tag="RHX21_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDV1988324.1"
                     /translation="MPDHSLFRLRVLPCCVALAMSGSYVNAWAEDEIQFDSRFLELKG
                     DTKIDLKRFSSQGYVEPGKYNLQVQLNKQPLTEEYDIYWYASENDASKTYACLPPELV
                     AQFGLKEDVAKNLQWIHDGKCLKPGQLEGIDIKADLSQSALVISLPQAYLEYTDINWD
                     PPSRWDDGISGLIADYSITAQTRHEENGGDDSNEISGNGTVGVNLGAWRLRADWQTDY
                     LHSKSNDDDVINGDDTQKNWEWSRYYAWRALPSLKAKLGLGEDYLNSDIFDGFNYVGG
                     SISTDDQMLPPNLRGYAPDISGVAHTTAKVTVSQMGRVIYETQVPAGPFRIQDLGDSV
                     SGTLHIRIEEQNGQVQEYDINTASMPFLTRPGQVRYKLMMGRPQEWGHHVEGGFFSGG
                     EASWGIANGWSLYGGALADEHYQSAALGVGRDLSVFGAVAFDVTHSHTRLDKETAYGK
                     GSLDGNSFRVSYSKDFDELNSRVTFAGYRFSEENFMTMSEYLDASDSEMVRTGNDKEM
                     YTATYNQNFRDAGVSVYLNYTRHTYWDRDEQTNYNIMLSHYFNLGSIRNMSISMTGYR
                     YEYDNQSDKGVYISLSMPWGDSSTISYNGNYGSGSDSSQVGYFSRVDDATHYQLNVGT
                     SDNHSSVDGYYSHDGSLAQVDLSANYHEGQYTSAGISLQGGATLTAQGGALHRTQNMG
                     GTRLLIDADGVAGVPVEGNGAAVYTNMFGKAVVADVNNYYRNQAYIDLNNLPENAEAT
                     QSVVQATLTEGAIGYRKFSVISGQKAMAVLRLQDGSYPPFGAEVKNDSAQNVGLVDDD
                     GNVYLAGVKPGEHMIVSWGGVAHCDIHLPDPLPADLFNGLLLPCQQTGAISPSMPHEI
                     KPMIQEQTQQVMPTEAPVSVSAN"
     gene            3333..4085
                     /locus_tag="RHX21_003173"
     CDS             3333..4085
                     /locus_tag="RHX21_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HDV1988325.1"
                     /translation="MTNLFCSAKKSTMLLALLLTTASLSAQASVTPDRTRLIFNESDK
                     SISVTLRNNDPKMPYLAQSWMEDEQGNRISSPLTVLPPVQRIDSMMNGQVKVQGMPDI
                     NKLPADRESVFYFNVREIPPKSNKPNTLQIALQTRIKLFWRPKALENVSMKKPWQHKV
                     TLTRSGQEFTVNNPTPYYVVISNASAQKNGNPAAGFSPMVISPKTSVPLKVKMDSVPV
                     LSYVNDYGARMPLYFKCGGDTCQVDVEQSRKG"
     gene            4101..4604
                     /locus_tag="RHX21_003174"
     CDS             4101..4604
                     /locus_tag="RHX21_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001248900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV1988326.1"
                     /translation="MRQIFVVGVGILLLGVSGIYNIILANSKPVDLILQVHVDPPPPC
                     SVTGSSVDFQTVNINDINGSNYRKDAGYTLSCPDRKADDLRMQLRGNTTTINGEKVVD
                     VGVPGFGIRIENADNNSLFSIGENNWTPFNITSQPKLNAVPVKQSGAQLSGADFSGSL
                     TMVVDYQ"
     gene            4601..5077
                     /locus_tag="RHX21_003175"
     CDS             4601..5077
                     /locus_tag="RHX21_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV1988327.1"
                     /translation="MKILLYLLLCMSSGIVNASPDITFKGTLVLPPACTISDGNTIEV
                     EFRDVIIDSIDGNNGREVVPYDIKCDAVTPGSSWDMTLTWIGTQTSYDDAAIETDVTG
                     LGIKLRQNGQPFRVNTPIQINADTKPQLEAVPVKAVDAVLTDGTFSASATLRVEYQ"
     gene            5074..5598
                     /locus_tag="RHX21_003176"
     CDS             5074..5598
                     /locus_tag="RHX21_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV1988328.1"
                     /translation="MKMKTWFALIVMLLLAGNSTARADNNLHFYGNLLSKSCTLVVQG
                     QVLAEVHFPSISSRDLMSREQSDRVPVVFQLKDCKGPVGYKVRVTLTGTEDSDLPGFL
                     ALDASSGAQGVSIGMETVDGIQVPINNSAGAIFNLSNGANNLNFKAWLQAKSGREVTS
                     GEFTASLTAIFEYI"
     gene            5599..6438
                     /locus_tag="RHX21_003177"
     CDS             5599..6438
                     /locus_tag="RHX21_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001383353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2544 domain-containing protein"
                     /protein_id="HDV1988329.1"
                     /translation="MKIKVILFGMLLFGLNSSVQADVTFNNVQTYGASYGSGLTTSIV
                     YKIDVLTPEGAYYGTYSQGGIMVQAGVVPNLTWTGPGVPPDITIPPGRAPIVDDSYCP
                     GMTSGWVCHRLPVNVHVTGTTHGCPWVVTTSIYSTARPPQAGPYYYQGPNAHQSNCPT
                     EPVASYDISWDENTVVHNKSLSLQSTGGVIEKSLPTFLMKDGRLCDGSDFSDDRGAYC
                     RLVSQLMTFSVQGCDNNKVNVTANRHPVTDKQLHDMQVRVDTSERQSFDATCRFQYIL
                     NEL"
     gene            complement(6552..7103)
                     /gene="smrB"
                     /locus_tag="RHX21_003178"
     CDS             complement(6552..7103)
                     /gene="smrB"
                     /locus_tag="RHX21_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease SmrB"
                     /protein_id="HDV1988330.1"
                     /translation="MKKKTTLSEEDQALFRQLMAGTRKIKQDTIVHRPQRKKVSEVPV
                     KRLIQEQADASHYFSDEFQPLLNTEGPVKYVRPDVSHFEAKKLRRGDYSPELFLDLHG
                     LTQLQAKQELGALIAACRREHVFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPK
                     EYGGDAALLVLIEVEEWLPPELP"
     gene            7269..8201
                     /gene="prmB"
                     /locus_tag="RHX21_003179"
     CDS             7269..8201
                     /gene="prmB"
                     /locus_tag="RHX21_003179"
                     /EC_number="2.1.1.298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3 N(5)-glutamine
                     methyltransferase"
                     /protein_id="HDV1988331.1"
                     /translation="MDKIFVDEAVNELQTIQDMLRWSVSRFSAANIWYGHGTDNPWDE
                     AVQLVLPSLYLPLDIPEDMRTARLTSSEKHRIVERVIRRVNERIPVAYLTNKAWFCGH
                     EFYVDERVLVPRSPIGELINNKFAGLISKQPQHILDMCTGSGCIAIACAYAFPEAEVD
                     AVDISPDALAVAEQNIEEHGLIHNVIPIRSDLFRDLPKVQYDLIVTNPPYVDAEDMSD
                     LPNEYRHEPELGLASGTDGLKLTRRILGNAADYLADDGVLICEVGNSMVHLMEQYPDV
                     PFTWLEFDNGGDGVFMLTKEQLLAAREHFAIYKD"
     gene            8236..9321
                     /gene="aroC"
                     /locus_tag="RHX21_003180"
     CDS             8236..9321
                     /gene="aroC"
                     /locus_tag="RHX21_003180"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HDV1988332.1"
                     /translation="MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHD
                     LDRRRPGTSRYTTQRREPDQVKILSGVFEGVTTGTSIGLLIENTDQRSQDYSAIKDVF
                     RPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAKKFGIEIRGCLTQM
                     GDIPLEIKDWSQVEQNPFFCPDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGL
                     GEPVFDRLDADIAHALMSINAVKGVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGI
                     LGGISSGQQIIAHMALKPTSSITVPGRTINRFGEEVEMITKGRHDPCVGIRAVPIAEA
                     MLAIVLMDHLLRQRAQNADVKTDIPRW"
     gene            9325..10149
                     /gene="mepA"
                     /locus_tag="RHX21_003181"
     CDS             9325..10149
                     /gene="mepA"
                     /locus_tag="RHX21_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-insensitive murein endopeptidase"
                     /protein_id="HDV1988333.1"
                     /translation="MNKTAIALLALLASSASLAATPWQKITQPVPGSAQSIGSFSNGC
                     IVGADTLPIQSEHYQVMRTDQRRYFGHPDLVMFIQRLSSQVSNLGMGTVLIGDMGMPA
                     GGRFNGGHASHQTGLDVDIFLQLPKTRWTSAQLLRPQALDLVSRDGKHVVSTLWKPEI
                     FSLIKLAAQDKDVTRIFVNPAIKQQLCLDAGTDRDWLRKVRPWFQHRAHMHVRLRCPA
                     DSLECEDQPLPPPGDGCGAELQSWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVI"
     gene            10149..10958
                     /locus_tag="RHX21_003182"
     CDS             10149..10958
                     /locus_tag="RHX21_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDV1988334.1"
                     /translation="METFNSLFMVSPLLLGVLFFVAMLAGFIDSIAGGGGLLTIPALM
                     AAGMSPANALATNKLQACGGSISATIYFIRRKVVSLSDQKLNIAMTFIGSMSGALLVQ
                     YVQADVLRQILPILVICIGLYFLLMPKLGEEDRQRRMYGLPFALIAGGCVGFYDGFFG
                     PAAGSFYALAFVTLCGFNLAKATAHAKLLNATSNIGGLLLFILGGKVIWATGFVMLVG
                     QFLGARMGSRLVLSKGQKLIRPMIVIVSAVMSAKLLYDSHGQEILHWLGMN"
     gene            10958..11506
                     /gene="epmC"
                     /locus_tag="RHX21_003183"
     CDS             10958..11506
                     /gene="epmC"
                     /locus_tag="RHX21_003183"
                     /EC_number="1.14.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P hydroxylase"
                     /protein_id="HDV1988335.1"
                     /translation="MNSTHHYEQLIEIFNSCFADDFNTRLIKGDDEPIYLPADAEVPY
                     NRIVFAHGFYASAIHEISHWCIAGKARRELVDFGYWYCPDGRDAQTQSQFEDVEVKPQ
                     ALDWLFCVAAGYPFNVSCDNLEGDFEPDRVVFQRRVHAQVMDYLTNGIPERPARFIKA
                     LQNYYHTPELTAEQFPWPEALN"
     gene            11540..11818
                     /locus_tag="RHX21_003184"
     CDS             11540..11818
                     /locus_tag="RHX21_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcL family protein"
                     /protein_id="HDV1988336.1"
                     /translation="MIAEFESRILALIDGMVDHASDDELFASGYLRGHLTLAIAELES
                     GDDHSAQAVHTTVSQSLEKAIGAGELSPRDQALVTDMWENLFQQASQQ"
     gene            complement(11939..13945)
                     /gene="mnmC"
                     /locus_tag="RHX21_003185"
     CDS             complement(11939..13945)
                     /gene="mnmC"
                     /locus_tag="RHX21_003185"
                     /EC_number="1.5.-.-"
                     /EC_number="2.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA
                     (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase
                     MnmD/FAD-dependent
                     5-carboxymethylaminomethyl-2-thiouridine(34)
                     oxidoreductase MnmC"
                     /protein_id="HDV1988337.1"
                     /translation="MKHYSIQPANLEFNAEGTPVSRDFDDVYFSNDNGLEETRYVFLG
                     GNQLEARFPEHLHPLFVVAESGFGTGLNFLTLWQAFDQFREAHPQAQLQRLHFISFEK
                     FPLTRADLALAHQHWPELAPWAEQLQAQWPMPLPGCHRLLLDEGRVTLDLWFGDINEL
                     ISQLDDSLNQKVDAWFLDGFAPAKNPDMWTQNLFNAMARLARPGGTLATFTSAGFVRR
                     GLQEAGFTMQKRKGFGRKREMLCGVMEQTLPLPCSTPWFNRTGSSKREVAIIGGGIAS
                     ALLSLALLRRGWQVTLYCADEVPALGASGNRQGALYPLLSKHDEALNRFFSNGFTFAR
                     RFYDQLPVKFDHDWCGVTQLGWDEKSQHKIAQMLSMDLPEELAVAVEANAVEQITGVA
                     TNCSGITYPQGGWLCPAELTRNVLKLAQQQGLQIYYQYQLQDLSRKDDCWLLNFAGDQ
                     QATHSVVVLANGHQISRFSQTSSLPVYSVAGQVSHIPTTPELAKLKQVLCYDGYLTPQ
                     NPANQHHCIGASYHRGSEDTAYSEDDQQQNRQRLIDCFPQAQWAKEVDISEKEARCGV
                     RCATRDHLPMVGNVPDYEATLVEYASLVEQKDKAVSAPVYDDLFMLDALGSRGLCSAP
                     LCAEILAAQMSEEPIPMDASTLAALNPNRLWVRKLLKGKAVKAG"
     gene            14104..15324
                     /gene="fabB"
                     /locus_tag="RHX21_003186"
     CDS             14104..15324
                     /gene="fabB"
                     /locus_tag="RHX21_003186"
                     /EC_number="2.3.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase I"
                     /protein_id="HDV1988338.1"
                     /translation="MKRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDSGM
                     RSHVWGNVKLDTTGLIDRKVVRFMSDASIYAFLSMEQAIADAGLSPEAYQNNPRVGLI
                     AGSGGGSPRFQVFGADAMRGPRGLKAVGPYVVTKAMASGVSACLATPFKIHGVNYSIS
                     SACATSAHCIGNAVEQIQLGKQDIVFAGGGEELCWEMACEFDAMGALSTKYNDTPEKA
                     SRTYDAHRDGFVIAGGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVAPSGEG
                     AVRCMQMAMHGVDTPIDYLNSHGTSTPVGDVKELAAIREVFGDKSPAISATKAMTGHS
                     LGAAGVQEAIYSLLMLEHGFIAPSINIEELDEQAAGLNIVTETTDRELTTVMSNSFGF
                     GGTNATLVMRKLKD"
     gene            15624..16802
                     /locus_tag="RHX21_003187"
     CDS             15624..16802
                     /locus_tag="RHX21_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose transporter"
                     /protein_id="HDV1988339.1"
                     /translation="MTAVSQTETRSSANFSLFRIAFAVFLTYMTVGLPLPVIPLFVHH
                     ELGYGNTMVGIAVGIQFLATVLTRGYAGRLADQYGAKRSALQGMLACGLAGGALLLAA
                     ILPVSAPFKFALLVVGRLILGFGESQLLTGALTWGLGIVGPKHSGKVMSWNGMAIYGA
                     LAVGAPLGLLIHSHYGFAALALTTMALPLLAWACNGTVRKVPALAGERPSLWSVVGLI
                     WKPGLGLALQGVGFAVIGTFVSLYFASKGWAMAGFTLTAFGGAFVVMRVMFGWMPDRF
                     GGVKVAIVSLLVETVGLLLLWQAPGAWVALAGAALTGAGCSLIFPALGVEVVKRVPSQ
                     VRGTALGGYAAFQDIALGVSGPLAGMLATTFGYSSVFLAGAISAVLGIIVTILSFRRG
                     "
     gene            complement(16799..17794)
                     /gene="flk"
                     /locus_tag="RHX21_003188"
     CDS             complement(16799..17794)
                     /gene="flk"
                     /locus_tag="RHX21_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulator Flk"
                     /protein_id="HDV1988340.1"
                     /translation="MIQPISGPPPGQPPGQGDNLPSGAGNQPLSSQQRTSLESLMTKV
                     TSLTQQQRAELWAGIRHDIGLSGDSPLLSRHFPAAEHNLAQRLLAAQKSHSARQLLAQ
                     LGEYLRLGNNRQAVTDYIRHNFGQTPLNQLSPEQLKTILTLLQEGKMVIPQPQQREAT
                     DRPLLPAEHNALKQLVTKLAAATGEPSKQIWQSMLELSGVKDGELIPAKLFNHLVTWL
                     QARQTLSQQNTPTLESLQMTLKQPLDASELAALSAYIQQKYGLSAQSSLSSAQAEDIL
                     NQLYQRRVKGIDPRDMQPLLNPFPPMMDTLQNMATRPALWILLVAIILMLVWLVR"
     gene            complement(18062..>18893)
                     /locus_tag="RHX21_003189"
     CDS             complement(18062..>18893)
                     /locus_tag="RHX21_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type VI secretion protein"
                     /protein_id="HDV1988341.1"
                     /translation="AATEHKNFNAVLQCRAIENNKDRLSCYDKSIQPTRTKVAEKFES
                     RDQCPDEKDDDRRLSCYDRFFSPTFTPSVNSKSKTEKPVTTEAQQPNLSEISKCRAEN
                     DKEARLNCYDKLFPQDKAVQAESKLEKATDVGKWHTSITTSPIDDSKNVILSLESDDY
                     IRTPFGEAVTPTLFIACREKKTEVFLSWDVYLGLEQTSMLYRLDKQKAVERNWLVSTD
                     TKAVFYKGNDIDFIRKLANSSKMYTKITPYNESPVSATFNLNGLSNALKPLQAACNWK
                     "
BASE COUNT         4546 a         4731 c         4922 g         4694 t
ORIGIN      
        1 attatttatg gtttaaggac aaataatgag taagtttgta aaaacagcta ttgctgcaac
       61 aatggtaatg ggtgcgttcg cttctacttc aacaatcgcc gctggcaaca atggtacagc
      121 acgtttctac ggcaccattg aagattcccc gtgctccatc gttcctgatg atcacaaact
      181 ggaagttgat atgggtgaca ttggttcagg gatcctgaaa aacaacggga cttctacacc
      241 gaaagctttc cagatccatc tgcaagactg tgtgtttgac acccagacaa cgatgaccac
      301 taccttcacc ggtaacgcgt cttctaccaa cagcggcaat tactacacca tttacaatac
      361 cgatactggt gcggcattta acaatgtcag cctggccatt ggtgacgctc agggaacctc
      421 ttataaaagc ggcgcgggta tcgaacagaa aatcgtaaac gatacggcga ccaacaaagg
      481 caaagcgaag cagacgctgg actttaaagc ctggctggtg ggcgctgctg atgcgccaga
      541 tttaggtaat tttgaagcca acacgacctt ccagattact tatctctaag tgataccccc
      601 atagctttcg ggctatgggg tttttaaatg gaattcgcgc aaattataat aattacggat
      661 ggatacgtgt atgcctgacc attctctttt ccgactgcgg gtacttccct gctgcgttgc
      721 attggcaatg tccgggagtt atgtcaatgc ctgggctgaa gatgaaattc agtttgattc
      781 ccgttttctg gagttaaaag gcgacacaaa aatcgatctg aagcgatttt ccagccaggg
      841 ttatgtcgag cctgggaaat acaatttaca ggttcaacta aataaacagc cgctgacgga
      901 agaatacgat atttactggt acgcctctga gaacgatgcc agtaaaacct atgcctgcct
      961 gccgcctgaa ctggtcgcgc agtttggctt aaaagaggat gtggcaaaaa acctgcaatg
     1021 gatccacgac ggcaaatgcc tgaaacccgg tcaactggaa ggcattgata ttaaagctga
     1081 cctgagtcag tcagcgttag tcatttcatt accccaggct taccttgaat ataccgacat
     1141 caactgggat ccgccttcac gctgggatga cggtatatct ggtttaattg ctgactacag
     1201 tattaccgct cagacacgac atgaagaaaa tggcggggat gacagcaatg aaattagcgg
     1261 caacgggacg gttggggtga acctcggcgc atggcgtctg cgagccgact ggcagactga
     1321 ttatttgcat agtaaaagca atgatgacga tgttatcaac ggtgatgaca cgcaaaaaaa
     1381 ctgggagtgg agccgctact acgcctggcg agccttaccg tcgctaaaag ccaaacttgg
     1441 ccttggcgaa gactacctta attctgatat tttcgacggc tttaactacg tgggtggcag
     1501 tatcagcacc gacgatcaaa tgttgccgcc gaatctgcgc ggctatgcgc cggatatctc
     1561 cggcgtggcg cacaccaccg cgaaagtgac cgtcagccag atgggccgcg tgatttacga
     1621 aactcaggtc ccggcggggc cgttccgtat ccaggacctt ggcgattccg tctccggtac
     1681 gctgcatatc cgcattgaag agcagaacgg tcaggtgcag gaatatgaca ttaacactgc
     1741 gtcaatgccg ttcctgaccc gccccggcca ggtgcgctat aaactgatga tgggccgccc
     1801 gcaggagtgg gggcaccacg tggaaggcgg tttcttctcc ggcggcgaag cttcctgggg
     1861 gattgccaac ggctggtcgc tatacggcgg ggcgctggca gatgaacact atcagtcggc
     1921 ggcgcttggc gtcggtcgcg atctgtctgt gtttggtgcg gtggcctttg atgtcaccca
     1981 ctcgcatacc cgcctggata aagaaactgc ctacggtaaa ggttcactgg acggtaactc
     2041 gtttcgcgtg agctattcca aagacttcga tgaactgaac agccgcgtca cttttgccgg
     2101 ataccgcttc tcggaagaga acttcatgac catgagcgag tatctcgatg ccagcgacag
     2161 cgaaatggtg cgcaccggca acgacaaaga gatgtacacc gccacctaca accagaactt
     2221 cagggatgcc ggtgtatctg tttatctcaa ctacacccgc catacctact gggatcgcga
     2281 cgaacagact aactacaaca tcatgctctc gcactacttc aacctgggca gtatccgcaa
     2341 catgagcatt tccatgaccg gataccgcta cgagtatgac aaccagtccg ataaaggtgt
     2401 ttacatatcg ctcagcatgc cgtggggtga cagcagcacc atcagctata acggcaacta
     2461 cggcagcggt tcggacagca gccaggtggg gtatttcagc cgtgtcgatg acgcaaccca
     2521 ttaccagttg aacgtaggca ccagcgacaa tcactccagc gttgacggtt attacagcca
     2581 cgacggatcg ctggcgcagg tcgatctcag cgccaactat catgaaggac agtacacctc
     2641 ggcaggtatt tccttacagg gcggcgcgac gctgaccgcg cagggtggcg cgctccaccg
     2701 tacccagaat atgggcggta cgcgcctgct gattgatgcc gatggcgtgg ccggtgttcc
     2761 ggtggaagga aacggtgcgg cggtttacac caatatgttc ggtaaggccg tggtggccga
     2821 cgtcaacaac tactaccgca accaggcgta tatcgacctt aacaacctgc cggaaaacgc
     2881 cgaagccacc cagtccgtgg tgcaggcgac gcttaccgaa ggagccattg gctaccgtaa
     2941 gttttcggtg atcagcgggc aaaaagcgat ggcggtgctg cgtctgcaag atggcagtta
     3001 tccgccgttt ggcgcggaag tgaaaaacga cagcgcgcag aacgtcggtc tggttgacga
     3061 tgacggcaac gtctacctcg cgggcgtcaa acctggcgag catatgatcg tttcatgggg
     3121 cggtgtggcc cactgcgata ttcatctgcc tgacccgctg ccagccgatc tgttcaatgg
     3181 cctgttatta ccatgccagc aaacaggggc gatatctcct tcgatgcctc atgaaattaa
     3241 gccgatgatc caggagcaga cccagcaggt gatgccaacg gaagcaccgg tatcggtatc
     3301 cgccaattaa taacgtgatt aaggaatgat ccatgacgaa tctattttgc tctgccaaaa
     3361 aatccacaat gttgctggca ttgctactaa ccactgccag cctgtcagca caggcctctg
     3421 tcacgccaga ccgtacacgc ctgattttta atgagagtga taaatcaatc agcgtcacgc
     3481 tgcgtaataa cgacccgaaa atgccgtatc tggcacaaag ctggatggaa gatgaacagg
     3541 gtaacaggat tagctcgcca ctgacggtcc tgccgccggt gcagcgcatc gattccatga
     3601 tgaacggcca ggtgaaggtg caggggatgc cggatatcaa caagctgcct gccgaccgcg
     3661 agagcgtgtt ctacttcaac gtgcgtgaaa ttccgccgaa atcgaataaa cccaacacgt
     3721 tacagatagc gctgcaaacg cgcatcaagc tgttctggcg accaaaggcg ctggaaaacg
     3781 tcagcatgaa aaaaccgtgg cagcataagg tgaccttaac ccgcagcggt caggagttta
     3841 ccgtcaataa tcctacgccg tactacgtgg ttatcagtaa cgccagcgcg cagaaaaatg
     3901 gcaatccggc agcgggattt tcccccatgg tgatatcgcc aaaaacctct gtgccgttaa
     3961 aagtcaaaat ggatagcgtc ccggtgctgt cttacgtcaa cgactatggc gcacggatgc
     4021 cgctgtattt taaatgtggc ggtgatacct gccaggtgga tgtagagcag agccgcaaag
     4081 gctgatgccg ggagagcgac atgagacaaa tttttgttgt gggggtgggt atattactgc
     4141 tgggcgttag tgggatatat aacattatcc ttgcaaattc aaaacctgtt gatctcattt
     4201 tacaggtaca tgtagatcct cctccgccat gtagcgtaac ggggagttca gtagattttc
     4261 agactgtgaa tatcaacgat atcaatggta gtaattatcg taaagatgca ggatatacgt
     4321 tgtcatgccc tgaccgaaaa gctgatgatt tacgtatgca gttgagagga aacaccacca
     4381 caattaatgg agaaaaagtc gttgatgtag gggttccagg atttggtatt cgaatcgaga
     4441 atgcagataa caactcacta ttctccattg gagaaaacaa ctggacccct ttcaatatca
     4501 catcacagcc gaaacttaat gcagtcccgg taaaacaaag tggtgcacaa ctttcagggg
     4561 ccgattttag tgggagttta acaatggtgg tggattatca atgaaaatac tcttgtattt
     4621 attgctctgt atgagcagcg gtattgtgaa tgcatcaccg gatatcacct tcaaaggaac
     4681 tcttgtattg cctccggcat gtactattag tgatggaaac actatcgagg tggagttcag
     4741 ggatgtaatt atcgatagca ttgatggaaa taatgggcga gaggtcgtgc cctacgatat
     4801 taaatgtgat gctgttacac ccggtagttc ctgggatatg acattgacat ggataggcac
     4861 acaaacaagt tatgatgatg ctgcaatcga aactgatgta acaggattag ggattaaact
     4921 tcggcaaaat ggtcagccat ttagagtaaa tacaccgata caaattaacg ccgatacgaa
     4981 accacaatta gaggctgtcc ccgtgaaggc ggtagatgct gtattaacag acggaacgtt
     5041 ttcagcttcg gccacattac gggtggaata tcaatgaaga tgaaaacctg gttcgcactc
     5101 atcgtaatgc tgttactggc aggaaatagc acagcgcgtg cagacaataa tttgcacttc
     5161 tacggaaatt tattaagtaa atcttgtacc ctggtagtac aaggacaagt gctggctgaa
     5221 gtccatttcc caagtatcag cagcagagat ttaatgtcac gggaacaatc tgatcgtgtg
     5281 ccggtcgttt ttcaattgaa agattgcaaa gggcctgttg gttacaaagt tagagttacg
     5341 ttaaccggta ccgaagatag cgatttgcca gggtttctgg ctttggatgc atcatcgggt
     5401 gcgcaaggtg tgagcattgg catggaaaca gttgatggga tacaggtccc catcaacaat
     5461 tcggcagggg caatatttaa cctgagtaac ggtgctaata atcttaactt taaggcttgg
     5521 ttgcaggcga aatctgggcg tgaagtcact tctggtgaat ttactgccag cctgacggca
     5581 atttttgagt atatctaaat gaaaataaaa gtgattttat ttggtatgtt attgttcggg
     5641 cttaattctt ctgtacaagc agacgttaca tttaataatg ttcagactta tggcgcatct
     5701 tatggcagtg ggctaacaac atctatcgtt tataaaatag atgtgttaac ccctgaaggg
     5761 gcatattatg ggacatattc acaagggggg attatggtac aggcaggagt tgtgcctaac
     5821 ttaacctgga ctggaccggg tgtcccccca gacataacaa ttccgccagg gcgggcaccg
     5881 atagtagatg attcttattg tcccggtatg acctctggtt gggtttgtca tagacttcct
     5941 gtaaatgtac atgttacggg tacaacccat ggttgccctt gggtggtgac aacatcaatt
     6001 tatagcacag caaggcctcc gcaggcgggg ccatattatt atcaggggcc gaatgcgcac
     6061 caatcaaatt gtccaacaga gccagtagca agctatgata tttcctggga tgaaaacacc
     6121 gttgttcata ataaatcatt aagcctgcaa tctacggggg gggttattga gaaatcgttg
     6181 ccgacattct taatgaaaga tgggcgatta tgtgatggca gtgacttcag tgatgaccgt
     6241 ggagcctatt gtcgcctggt atcacaatta atgacgttta gtgtccaggg ttgtgataac
     6301 aataaagtga acgtaacggc aaaccgacat cctgtaactg ataaacaact ccatgacatg
     6361 caggtgcgtg ttgatactag tgaacggcaa agttttgatg ctacatgtcg ctttcaatat
     6421 attcttaatg aactttaatt aatattatta gcctcgacag tgttcgtagc cggataaggc
     6481 gtttaccccg catccggcat ttggtcccag cattcagggc gaaatggcaa aacgcatccg
     6541 ccccctaata ttcatggcaa ctccggcggt agccactctt ccacttcaat caacactaac
     6601 aacgctgcat ctccgccgta ctctttcggc gcctggtgaa atgccattac atgcggatgt
     6661 tgtgccagcc acagcggcgt ttgctgtttt aaaatatgct tcccgtgccc gtgcattacg
     6721 caagcgcaaa acacatgttc acggcggcag gcggcaatca acgcccccag ttcctgcttg
     6781 gcctgtagct gcgtcagacc gtgtaaatcc aaaaacaatt ccggcgaata atcaccgcgt
     6841 cgcaacttct tcgcttcaaa atgactaaca tccgggcgga catatttcac tgggccttcg
     6901 gtattcagta acggctgaaa ctcatctgag aaataatggc tggcatcagc ctgctcctgg
     6961 atcaagcgtt tcaccggcac ttcgctgact tttttacgct gtggccgatg gacaatggtg
     7021 tcctgcttaa tcttgcgagt ccccgccatc aactggcgaa acagagcctg gtcctcctcg
     7081 ctaagtgttg ttttcttttt catttatgcg tctctatttc taattttcct acagtttacc
     7141 cgactcgtag cgcaatcgat cgttttaaac gtatttttcc tcactcaccg cgcgtgaatg
     7201 ctgatttatc gtcatcttca tggcaaacta gccgccgaaa ttattgcgat catgccctgg
     7261 aggaatacgt ggataaaatt ttcgttgatg aagcagttaa tgagctgcaa accattcagg
     7321 acatgttgcg ctggtcggtt agccgcttca gcgcggcaaa tatctggtac ggtcacggca
     7381 ccgataaccc gtgggatgaa gcggtacaat tggtgttgcc gtcgctctac ctgccgctgg
     7441 atattccgga agatatgcgc accgcgcgtc tgacctccag cgaaaaacac cgtattgttg
     7501 agcgcgtgat ccgccgcgtc aacgaacgca ttccggtggc ttacctgacc aataaagcct
     7561 ggttctgcgg tcatgaattt tacgtcgatg aacgcgtgct ggtgccgcgc tcgccgattg
     7621 gtgaactgat caacaataaa tttgccgggc taatcagcaa gcaaccgcag catattttag
     7681 atatgtgtac cggtagcggc tgcattgcca ttgcctgtgc ttatgccttc ccggaagcag
     7741 aagtcgatgc ggtagatatc tctcccgacg cgctggcggt tgccgaacag aacatcgaag
     7801 aacacggtct gatccacaat gtcatcccga ttcgttccga tctgttccgt gatttgccga
     7861 aagtgcagta cgacctgatc gtcactaacc cgccgtatgt cgatgcggaa gatatgtccg
     7921 acctgccaaa tgaataccgc cacgagccgg aactgggcct ggcatctggc accgacggcc
     7981 tgaaactgac gcgtcgcatt ctcggtaacg cggcagatta ccttgctgat gatggtgtgc
     8041 tgatttgtga agtcggcaac agcatggtac atcttatgga acaatatccg gatgttccgt
     8101 tcacctggct ggagtttgat aacggcggcg atggtgtgtt tatgctcacc aaagagcagc
     8161 tgctggcggc ccgtgaacat ttcgcgattt ataaagatta agtaaacacg caaacacaac
     8221 aataacggag ccgtgatggc tggaaacaca attggacaac tctttcgcgt aaccaccttc
     8281 ggcgaatcgc acgggctggc gctcggctgc atcgtcgatg gtgttccgcc aggcattccg
     8341 ctaacagaag cggacctgca acatgacctc gaccgtcgtc gccctgggac atcgcgctat
     8401 accacccagc gccgcgaacc ggatcaggtc aaaattctct ccggtgtttt tgaaggtgtt
     8461 actaccggca ccagcatcgg tttgttgatc gaaaacactg atcagcgttc tcaggattac
     8521 agcgcaatta aagatgtttt ccgcccaggc catgctgatt acacctacga acaaaaatac
     8581 ggtctgcgtg attatcgcgg cggcgggcgc tcttccgctc gtgaaactgc catgcgtgtt
     8641 gcggcaggag cgattgccaa aaaatatctc gccaagaaat ttggcatcga aattcgcggc
     8701 tgcctgaccc agatgggcga cattccgctg gaaatcaaag actggtcgca ggtcgagcaa
     8761 aatccgttct tctgcccgga cccggacaaa atcgacgcgt tagatgaact gatgcgcgcg
     8821 ctgaaaaaag agggcgactc tattggtgcg aaagtcaccg ttgttgccag tggcgttcct
     8881 gccgggcttg gtgagccagt ttttgatcgc ctggatgccg acatcgccca tgcgctaatg
     8941 agcattaacg cggtgaaagg tgtggaaatt ggtgatggtt ttgacgtcgt agcgctgcgt
     9001 ggcagccaga accgcgacga aatcaccaaa gacggtttcc agagcaacca tgcgggcggc
     9061 attctcggcg gaattagcag cgggcagcaa atcattgctc atatggcact gaaaccgacc
     9121 tccagtatta ccgtgccggg gcgcaccatt aaccgctttg gcgaagaagt tgagatgatc
     9181 accaaaggcc gtcacgatcc ctgtgtcggg atccgcgcgg tgccgatcgc tgaagcgatg
     9241 ctggcgatcg ttttaatgga tcacctgcta cggcagcggg cgcaaaatgc cgatgtgaag
     9301 actgatattc cacgctggta aaaaatgaac aaaaccgcga ttgcgctgct ggccctgctt
     9361 gccagtagcg ccagcctggc agcgacgccg tggcaaaaaa taacccaacc tgtgccgggt
     9421 agcgcacaat cgataggcag tttttctaat ggctgtatcg tcggcgctga cacgctgccg
     9481 atacagtccg aacattatca ggtcatgcgt accgatcagc gtcgctattt cggtcacccg
     9541 gacctggtga tgtttatcca gcgtctgagt agccaggtga gcaatctggg catgggtacg
     9601 gtgctgattg gcgatatggg gatgcccgct ggtgggcgct tcaacggcgg tcatgccagc
     9661 caccagaccg gactggatgt cgatatcttt ctgcaactgc cgaaaactcg ctggacctcc
     9721 gcgcagctct tgcgcccgca agcactggac ttagtttccc gcgacggtaa acacgttgtc
     9781 tccacgctgt ggaagccgga aattttcagc ttgatcaaac tcgccgccca ggacaaagac
     9841 gtcacgcgca tttttgttaa tccggcgatt aaacaacaac tttgccttga tgcgggcacc
     9901 gatcgcgact ggttgcgcaa agtgcgaccc tggttccagc atcgtgcgca tatgcatgta
     9961 cgattacgtt gtcctgccga tagtctggag tgtgaagatc aacctttacc gccaccaggc
    10021 gatggttgcg gggcagaact gcaaagctgg tttgaacctc caaaaccggg aacaacaaag
    10081 cctgagaaga agacaccgcc tccgttgccg ccttcctgcc aggcgctact ggatgagcac
    10141 gtgatctaat ggaaacgttt aatagcctgt ttatggtttc cccgctgttg ctgggagttc
    10201 tcttttttgt cgccatgctg gcgggattta tcgactcgat tgccggtggc ggtgggttac
    10261 tcaccattcc ggcattgatg gcagcgggga tgtctcccgc taatgcgctg gcaaccaata
    10321 aactgcaagc ctgcggcggc tctatttccg ccactatcta ctttattcgc cgcaaagtgg
    10381 ttagtttaag tgatcagaaa ctcaatatcg ccatgacctt tatcggctca atgagcggcg
    10441 cactgctggt gcaatacgtt caggctgatg tcttacggca gattttgccc attctggtga
    10501 tttgtatcgg cctctatttc ttgctgatgc caaagctggg tgaagaagat cgccagcgcc
    10561 ggatgtacgg tttacccttc gcgttaattg ccggtggctg cgtcggtttt tatgacggat
    10621 tctttggtcc ggcagccgga tcgttttacg cgctggcctt tgttacgctg tgcggattca
    10681 acctcgccaa agccacggct cacgccaaat tactcaacgc aacgtcaaac atcggtggtt
    10741 tactgctgtt tattctcggc ggcaaagtga tttgggcgac gggctttgtg atgctggtgg
    10801 ggcagttcct cggcgcgcgc atgggttcaa gactggtgtt gagcaaagga caaaaactga
    10861 tccgcccgat gatcgttatc gtctcggcgg tgatgagtgc caaattactt tatgatagcc
    10921 acggacagga gatcctccac tggttgggga tgaactaatg aacagtacac accactatga
    10981 gcagttgatt gaaattttta atagctgctt tgccgatgat tttaataccc gtctgattaa
    11041 aggcgacgac gaaccgatct atcttcctgc tgatgcggaa gtaccgtata accgaatcgt
    11101 ctttgctcat ggcttttatg ccagcgcaat tcatgagatt tcgcactggt gtattgccgg
    11161 aaaagcgcgc cgtgagctgg ttgatttcgg ctactggtat tgcccggacg gacgcgatgc
    11221 ccaaacgcaa agccagtttg aagatgttga agtgaagccg caggcgctcg actggttgtt
    11281 ctgcgtggcg gcgggatatc cgtttaacgt cagttgcgac aatctggaag gcgacttcga
    11341 accggaccgc gtggtgtttc aacggcgagt acatgcgcag gtgatggatt atctaacaaa
    11401 tggcattccg gaacgcccgg cacgtttcat taaagcacta caaaattatt atcacacgcc
    11461 ggaacttacg gcggaacagt tcccgtggcc ggaagcgctc aactgaagcc agcgccacgt
    11521 tttacaatga ggaaagaaga tgatcgcgga gtttgaatca cgcattctgg cattaatcga
    11581 cggtatggtt gaccatgcca gtgatgatga gttgtttgcc agtgggtatt tgcgtggcca
    11641 cctgacatta gccatcgcag aattggaaag tggtgatgac cactccgctc aggcggtgca
    11701 tacgaccgtt agccagagtc tggaaaaagc cattggtgct ggtgaattgt cgccgcgtga
    11761 ccaggcgctg gtgaccgata tgtgggaaaa cctgtttcag caggcgtcac agcagtaagt
    11821 tgcggcgtct ggagcaccat gcctgatgcg acgcttatcg cgtcttatca ggcctacacg
    11881 tcacacttag gtcggataag gcgttcacgc cgcatccgac aaacaatgcc aaagctggtt
    11941 acccagcctt aactgcttta cccttcaaca atttccgcac ccataaccga ttcggattta
    12001 acgccgccag cgtactggca tccatcggaa tcggttcttc actcatctgt gccgccagaa
    12061 tctctgcgca cagtggggca gaacacaaac cacgcgaacc caaagcatca agcataaaga
    12121 gatcgtcata aaccggcgcg cttaccgcct tatctttctg ctccaccagc gacgcatatt
    12181 ccacgagtgt tgcctcataa tcgggaacat tacctaccat tggcagatga tcgcgggtgg
    12241 cacaacgcac accgcagcgc gcctctttct cactgatatc aacctctttt gcccactgtg
    12301 cctgtgggaa acaatcaatc aaccgctggc gattctgctg ctgatcgtcc tcactgtacg
    12361 ccgtatcttc gctgccgcga tgataactgg caccaataca atgatgctga ttcgccggat
    12421 tttgtggcgt gagataaccg tcatagcaca gcacctgctt cagttttgcc agttccggtg
    12481 tcgtcggaat atggctgacc tgaccggcaa ccgaatatac tggcagagat gatgtttggc
    12541 tgaaacggct gatttgatgc ccgttcgcca gtaccactac gctgtgtgtt gcttgctgat
    12601 ctcctgcaaa attcaacaac caacagtcat ccttacggga taaatcctgt aactgatatt
    12661 gataataaat ctgcaaaccc tgctgttgcg ccagtttcag cacattacgg gtcagttctg
    12721 ctgggcacag ccaaccacct tgcggataag taatgccgct gcaatttgtc gcaacgcccg
    12781 taatttgttc aaccgcattt gcctcaacgg ctacagccag ttcttcgggt aaatccattg
    12841 acagcatctg tgcgatttta tgctggcttt tctcatccca gcctaactgc gtgacgccgc
    12901 accagtcatg atcaaattta acgggtaatt ggtcgtaaaa ccgacgagca aaagtaaacc
    12961 cattagagaa aaagcggttt agcgcctcat cgtgtttgct taataacgga tacaacgccc
    13021 cctggcgatt gccggaagca cccagcgcgg ggacttcatc cgcgcaataa agcgttactt
    13081 gccagccgcg acgcaatagc gccagcgaca acaatgcgct ggcaatacca ccgccgataa
    13141 tcgctacttc ccgtttgctg ctgcccgtac gattaaacca cggcgtggag caggggagtg
    13201 gtaatgtctg ttccatcacc ccacaaagca tttcccgttt gcgtccaaag cccttacgtt
    13261 tttgcatcgt gaatccggct tcctgcaaac cgcggcggac aaaaccggca gacgtaaatg
    13321 tcgccagcgt gccgcctgga cgcgccaacc ttgccatggc gttaaacaga ttttgcgtcc
    13381 acatatccgg gtttttcgct ggcgcaaagc cgtccagaaa ccaggcatct actttttgat
    13441 ttagagaatc gtccagttgg ctgatcagtt cattaatatc gccaaaccat aaatccagcg
    13501 tcacgcggcc ttcatcaagt aataaacgat ggcaaccggg caagggcatt ggccactgcg
    13561 cctgaagttg ttctgcccac ggagccagtt ccggccagtg ttgatgcgct aaggctaaat
    13621 ccgcacgggt gaggggaaat ttctcaaaac taatgaaatg taagcgttgt aattgcgctt
    13681 gcggatgcgc ttcgcgaaac tgatcaaatg cctgccatag cgtcaggaag tttaatccgg
    13741 tgccgaagcc gctctctgct accacaaaca gaggatgtag atgctcagga aagcgtgcct
    13801 ctaattggtt acctccgaga aaaacataac gcgtctcttc cagcccgtta tcgttggaaa
    13861 aatagacatc gtcaaaatct cgggaaacag gtgtaccctc agcattaaat tcgaggttgg
    13921 caggttgtat ggagtagtgt ttcacgtaag ttactcgtct tacaggcggt ggctcgatct
    13981 tagcgatgtg tgtaaggctg cgcaaatttc tctattaatt ggctgatcgg acttgttcgg
    14041 cgtacaagtg tacgctattg tgcattcgaa acttactcta tgtgcgactt acagaggtat
    14101 tgaatgaaac gtgcagtgat tactggcctg ggcattgttt ccagcatcgg taataaccag
    14161 caggaagtcc tggcatctct gcgtgaagga cgttcaggga tcactttctc tcaggagctg
    14221 aaggattccg gcatgcgtag ccacgtctgg ggcaacgtaa aactggatac cactggcctc
    14281 attgaccgca aagttgtgcg ctttatgagc gacgcatcca tttatgcatt cctttctatg
    14341 gagcaggcaa tcgctgatgc gggcctctct ccggaagctt accagaataa cccgcgcgtt
    14401 ggcctgattg caggttccgg cggcggctcc ccgcgtttcc aggtgttcgg cgctgacgca
    14461 atgcgcggcc cgcgcggcct gaaagcggtt ggcccgtatg tggtcaccaa agcgatggca
    14521 tccggcgttt ctgcctgcct cgccaccccg tttaaaattc atggcgttaa ctactccatc
    14581 agctccgcgt gtgcgacttc cgcacactgt atcggtaacg cagtagagca gatccaactg
    14641 ggcaaacagg acatcgtgtt tgctggcggc ggcgaagagc tgtgctggga aatggcttgc
    14701 gaattcgacg caatgggtgc gctgtctact aaatacaacg acaccccgga aaaagcctcc
    14761 cgtacttacg atgctcaccg tgacggtttc gttatcgctg gcggcggcgg tatggtggtg
    14821 gttgaagagc tggaacacgc gctggcgcgt ggtgctcaca tctatgctga aatcgttggc
    14881 tacggcgcaa cgtctgatgg cgcagacatg gttgctccgt ctggcgaagg cgcagtacgt
    14941 tgtatgcaga tggcgatgca tggcgttgat accccaatcg attacctgaa ctcccacggc
    15001 acttcgactc cggttggcga cgtgaaggag ctggcagcta tccgtgaagt gttcggcgat
    15061 aagagcccgg cgatttctgc aaccaaagcc atgaccggtc actctctggg cgctgctggc
    15121 gtacaggaag ctatctactc tctgctgatg ctggaacacg gctttatcgc cccgagcatc
    15181 aacattgaag agctggacga gcaggctgcg ggtctgaaca tcgtgaccga aacgaccgat
    15241 cgcgaactga ccactgttat gtctaacagc ttcggcttcg gcggcaccaa cgccacgctg
    15301 gtaatgcgca agctgaaaga ttaattcgca gtaggccgga gtaggtcgga taagacgcgc
    15361 cagcgtcgca tccgacgtta cacgtcagcg tcgcatccga cgttacgcgc caatgcggca
    15421 tccggcacta acgccaaagg gaacccgatg gttccctttt tcacatcatt gacaatcgcc
    15481 gcctgttcca ggcaaacttc ccgctttgtc gatttccttc tgaaaagacg tacgcgttaa
    15541 ttcctgccaa cgcaccgtaa ccctgaaacc agagagatga gacggggata ctcctcgcct
    15601 tgcgctgcat tctggagtaa tgcatgactg ctgtaagcca aaccgaaaca cgatcttctg
    15661 ccaatttttc gctcttccgc atcgcttttg cggtttttct cacctacatg accgtagggt
    15721 tgccgttgcc ggttatcccg ttgtttgttc atcatgaatt gggctatggc aataccatgg
    15781 tcggcattgc cgtcggcatt cagtttctgg ctacggtgct gacgcgtggt tacgccgggc
    15841 gactggccga tcaatatggc gcaaaacgtt cggcgcttca ggggatgtta gcttgtggtc
    15901 tggcgggggg cgcgttgctg ctggcggcga ttttgcccgt ctccgcaccg ttcaaatttg
    15961 ccctgttggt cgtcgggcgt ttgattcttg gctttggtga aagccagtta ctgacaggcg
    16021 ctctgacctg gggattaggc atcgtagggc caaaacactc tggcaaagta atgtcatgga
    16081 acggaatggc gatttacggt gccctcgctg ttggtgcacc gcttggcctg ttgattcata
    16141 gccattacgg ttttgccgca ctggcgctca ccacaatggc attaccctta ctggcgtggg
    16201 cctgtaacgg cacagtgcgc aaagtaccgg ccctggcggg agaacgtcca tcgctgtgga
    16261 gcgttgtcgg gcttatctgg aaaccagggt tagggctggc actacaaggc gttggttttg
    16321 cggttatcgg gactttcgtt tcgctctact ttgccagcaa aggatgggcg atggcgggct
    16381 ttactcttac cgcgtttggc ggcgcatttg tcgtgatgcg cgtcatgttt ggctggatgc
    16441 cggaccgttt tggcggcgtg aaagtggcga tcgtctctct gcttgtagaa acggtgggct
    16501 tgttgctgct ctggcaagcc ccgggtgcgt gggtcgcatt agcgggcgcg gcgttaaccg
    16561 gagccggatg ttcgcttatc tttcctgcgc tgggcgtgga ggtggttaaa cgtgtcccct
    16621 cacaagttcg cggcaccgca ctgggcggtt acgccgcgtt tcaggatatc gccctcggcg
    16681 tctccgggcc gctggcggga atgctggcga ccacgtttgg ttactcttcg gtatttcttg
    16741 ccggggcgat ctctgcggtg ctgggaatta ttgtcacgat actgtcgttt cgtcggggtt
    16801 aacgaaccag ccagaccagc atcaggataa tcgcgactaa cagtatccac agcgcgggac
    16861 gcgttgccat attttgcaac gtgtccatca tcggtggaaa aggattaagc agcggttgca
    16921 tatcacgcgg atcaatccct ttaacccgcc gttgataaag ctgattaaga atatcctcgg
    16981 cctgggcaga agaaagcgat gattgcgcag aaaggccata tttttgctgg atatatgccg
    17041 ataacgccgc cagttcactg gcatctaaag gttgttttag cgtcatttgt agtgattcca
    17101 gcgtcggcgt attttgctgg cttagcgtct gacgcgcctg cagccaggtc accagatggt
    17161 taaacagttt cgctggaatt aactcgccat ctttcacccc ggaaagttcc agcatcgatt
    17221 gccagatctg tttgctgggc tcccccgttg ccgccgcaag tttggtcacc agctgtttga
    17281 gcgcattgtg ctccgccggt aatagaggac gatcggtcgc ctcgcgctgc tgcggttgcg
    17341 gaataaccat cttgccttcc tgcaacaggg tgagaatggt ttttaattgc tccggtgaga
    17401 gctgattcag cggcgtctga ccaaagttat gacggatata atccgtgacc gcctgacgat
    17461 tattccccag acgtaaatac tcccctaatt gcgctaaaag ctggcgggca gaatggcttt
    17521 tttgcgcggc cagcagacgt tgcgccagat tatgctcagc ggcagggaag tgacgcgaaa
    17581 gcagcggtga atctcccgac agaccaatat cgtgcctgat acccgcccac agttctgctc
    17641 tttgctgttg cgtcagtgag gtcactttcg tcattaagct ttccagcgaa gtacgttgct
    17701 gactggataa aggctgattg cccgcgccag acggcaggtt atctccctga cctggtggtt
    17761 gcccaggagg agggccggaa ataggttgta tcattacgta tccttatacc tgaaatcttc
    17821 gcaagtatgc ctggccgcga gattatggca cacttgtccg gttaactctc gtctcataca
    17881 ggtaacacaa acgtgaaaat ccttgttgat gaaaaaaatg atgacttaat ttattgatgt
    17941 aaaaggattt atgtcagcgc gtgtccacgc agtgaccaca ttttcgagta cagataacac
    18001 aaagcccgtt ttcacgggct ttgtgttatc tgtgattgtg gctaagccac atgatttaat
    18061 actatttcca gttacaagca gcttgaagcg gttttagcgc gtttgacagg ccgtttaaat
    18121 tgaaagttgc acttacgggg ctctcattat aaggcgttat ttttgtatac attttgcttg
    18181 agttggctag ttttcggatg aaatcaatgt cattaccttt ataaaaaaca gcctttgtat
    18241 ctgtggatac tagccagttt cgctcaactg ctttctgttt atcaaggcga taaagcatgc
    18301 tggtttgttc aaggcctaaa tatacatccc aactaagaaa tacttcggtt ttcttttctc
    18361 ggcaagctat aaacagagta ggagtaaccg cttctccaaa tggagttctg atataatcat
    18421 cactttctaa cgataaaatt acatttttcg aatcatcaat tggcgatgta gtaatggatg
    18481 tgtgccattt tcctacatct gtggctttct ctaattttga ttcagcttga acggctttat
    18541 cctgtgggaa tagtttatcg tagcagttta gtctggcttc tttatcattt tctgcacgac
    18601 atttagatat ctcagaaaga tttggttgct gagcctctgt tgttactggc ttttccgttt
    18661 tagattttga gtttacagat ggagtaaatg ttggagaaaa gaaacgatca taacaagata
    18721 aacgtctatc atcatctttc tcatcagggc attgatctct gctttcgaat ttttcagcaa
    18781 ctttcgttcg agtcggttgt attgacttat cgtaacaaga aagtctgtct ttattatttt
    18841 ctattgctcg gcactggagt actgcattga agttcttatg ttcagttgct gcg
//
LOCUS       DAPGUL010000084        18588 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.085, whole genome shotgun sequence.
ACCESSION   DAPGUL010000084 DAPGUL010000000
VERSION     DAPGUL010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18588
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.085"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            122..1342
                     /locus_tag="RHX21_003190"
     CDS             122..1342
                     /locus_tag="RHX21_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HDV1988342.1"
                     /translation="MSIYKIPLPLNILEAARERITWTLNTLPRVCVSFSGGKDSGLML
                     HLTAELARQMGKKICVLFIDWEAQFSCTINYVQSLRELYTDVIEEFYWVALPLTTQNS
                     LSQFQPEWQCWEPDVEWVRQPPQDAITDPDFFCFYQPGMTFEQFVREFAEWFSQKRPA
                     AMMIGIRADESYNRFVAIASLNKQRFADDKPWTTAAPGGHSWYIYPIYDWKVADIWTW
                     YANHQSLCNPLYNLMYQAGVPLRHMRICEPFGPEQRQGLWLYHVIEPDRWAAMCARVS
                     GVKSGGIYAGHDNHFYGHRKILKPEHLDWQEYALLLLNSMPEKTAEHYRNKIAIYLHW
                     YQKKGIEVPQTQQGDIGAKDIPSWRRICKVLLNNDYWCRALSFSPTKAKNYQRYNERI
                     KGKRQEWGILCNND"
     gene            1315..1944
                     /locus_tag="RHX21_003191"
     CDS             1315..1944
                     /locus_tag="RHX21_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HDV1988343.1"
                     /translation="MGDTMQQRLTQDLTQFLASLPKDDRIKAINEIRMAIHQVSPFRE
                     EPVDCVLWVKNSQLMPNDYNPNNVAPPEKKLLKKSIEIDGFTQPIVVTHTDKNALEIV
                     DGFHRHEIGKGSSSLKLRLKGYLPVTCLEGTRNQRIAATIRHNRARGRHQITAMSEIV
                     RELSQLGWDDNKIGKELGMDSDEVLRLKQINGLQELFADRQYSRAWTVK"
     gene            complement(1945..3105)
                     /gene="ybdL"
                     /locus_tag="RHX21_003192"
     CDS             complement(1945..3105)
                     /gene="ybdL"
                     /locus_tag="RHX21_003192"
                     /EC_number="2.6.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine-oxo-acid transaminase"
                     /protein_id="HDV1988344.1"
                     /translation="MTNNPLIPQSKLPQLGTTIFTQMSALAQQHQAINLSQGFPDFDG
                     PRYLQERLAYHVAQGANQYAPMTGVQALREAIAQKTERLYGYQPDADSDITVTAGATE
                     ALYAAITALVRNGDEVICFDPSYDSYSPAIALSGGIVKRMALQPPHFRVDWQEFAALL
                     SERTRLVILNTPHNPSATIWQQADFAALWQAIAGHEIFVISDEVYEHINFSQQGHASV
                     LAHPQLRERAVAVSSFGKTYHMTGWKVGYCVAPAPISAEIRKVHQYLTFSVNTPAQLA
                     LADMLRAEPEHYLALPDFYRQKRDILVNALNESRLEILPCEGTYFLLVDYSEVSTLDD
                     VEFCQWLTQEHGVAAIPLSVFCADPFPHKLIRLCFAKKESTLLAAAERLRQL"
     gene            3214..4302
                     /gene="hcxA"
                     /locus_tag="RHX21_003193"
     CDS             3214..4302
                     /gene="hcxA"
                     /locus_tag="RHX21_003193"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxycarboxylate dehydrogenase HcxA"
                     /protein_id="HDV1988345.1"
                     /translation="MPHNPIRVVVGPANYFSHPGSFNHLNDFFTDEQLSRAVWIYGKR
                     AIAAAQTKLPPAFGLPGAKHILFRGHCSESDVQQLAAESGDDRSVVIGVGGGALLDTA
                     KALARRLGLPFVAAPTIAATCAAWTPLSVWYNDAGQALHYEIFDDANFMVLVEPEIIL
                     NAPQQYLLAGIGDTLAKWYEAVVLAPQPETLPLTVRLGINNAQAIRDVLLNSSEQALA
                     DQQNQQLTQSFCDVVDAIIAGGGMVGGLGDRFTRVAAAHAVHNGLTVLPQTEKFLHGT
                     KVAYGILVQSALLGQDDVLAQLTGAYQRFHLPTTLAELEVDINNQAEIDKVIAHTLRP
                     VESIHYLPVTLTPDTLRAAFEKVESFKA"
     gene            complement(4312..4509)
                     /locus_tag="RHX21_003194"
     CDS             complement(4312..4509)
                     /locus_tag="RHX21_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbdD/YjiX family protein"
                     /protein_id="HDV1988346.1"
                     /translation="MFDSLAKAGKYLGQAAKLMIGMPDYDNYVEHMRVNHPDQTPMTY
                     EEFFRERQDARYGGKGGARCC"
     gene            complement(4691..6796)
                     /gene="cstA"
                     /locus_tag="RHX21_003195"
     CDS             complement(4691..6796)
                     /gene="cstA"
                     /locus_tag="RHX21_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein CstA"
                     /protein_id="HDV1988347.1"
                     /translation="MNKSGKYLVWTVLSVMGAFALGYIALNRGEQINALWIVVASVCI
                     YLIAYRFYGLYIAKNVLAVDPTRMTPAVRHNDGLDYVPTDKKVLFGHHFAAIAGAGPL
                     VGPVLAAQMGYLPGMIWLLAGVVLAGAVQDFMVLFVSTRRDGRSLGELVKEEMGPTAG
                     VIALVACFMIMVIILAVLAMIVVKALTHSPWGTYTVAFTIPLALFMGIYLRYLRPGRI
                     GEVSVIGLVFLIFAIISGGWVAESPTWAPYFDFTGVQLTWMLVGYGFVAAVLPVWLLL
                     APRDYLSTFLKIGTIVGLAVGILIMRPTLTMPALTKFVDGTGPVWTGNLFPFLFITIA
                     CGAVSGFHALISSGTTPKMLANEGQACFIGYGGMLMESFVAIMALVSACIIDPGVYFA
                     MNSPMAVLAPAGTADVVASAAQVVSSWGFSITPDTLNQIASEVGEQSIISRAGGAPTL
                     AVGMAYILHGALGGMMDVAFWYHFAILFEALFILTAVDAGTRAARFMLQDLLGVVSPG
                     LKRTDSLPANLLATALCVLAWGYFLHQGVVDPLGGINTLWPLFGIANQMLAGMALMLC
                     AVVLFKMKRQRYAWVALVPTAWLLICTLTAGWQKAFSPDAKVGFLAIANKFQAMIDSG
                     NIPSQYTESQLAQLVFNNRLDAGLTIFFMVVVVVLALFSIKTALAALKEPKPTAKETP
                     YEPMPENVEEIVAQAKGAH"
     gene            complement(6977..7390)
                     /gene="entH"
                     /locus_tag="RHX21_003196"
     CDS             complement(6977..7390)
                     /gene="entH"
                     /locus_tag="RHX21_003196"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proofreading thioesterase EntH"
                     /protein_id="HDV1988348.1"
                     /translation="MIWKRHLTLDELNATSDNTMVAHLGIVYTRLGDDVLEAEMPVDT
                     RTHQPFGLLHGGASAALAETLGSMAGFMMTRDGQCVVGTELNATHHRPVSEGKVRGVC
                     QPLHLGRQNQSWEIVVFDEQGRRCCTCRLGTAVLG"
     gene            complement(7393..8139)
                     /gene="entA"
                     /locus_tag="RHX21_003197"
     CDS             complement(7393..8139)
                     /gene="entA"
                     /locus_tag="RHX21_003197"
                     /EC_number="1.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
                     EntA"
                     /protein_id="HDV1988349.1"
                     /translation="MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFAQEQY
                     PFATEVMDVADAAQVAQVCQRLLAETERLDVLVNAAGILRMGATDQLSKEDWQQTFAV
                     NVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGL
                     ELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEI
                     ANTILFLASDLASHITLQDIVVDGGSTLGA"
     gene            complement(8139..8996)
                     /gene="entB"
                     /locus_tag="RHX21_003198"
     CDS             complement(8139..8996)
                     /gene="entB"
                     /locus_tag="RHX21_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin biosynthesis bifunctional
                     isochorismatase/aryl carrier protein EntB"
                     /protein_id="HDV1988350.1"
                     /translation="MAIPKLQAYALPESHDIPKNKVDWAFEPQRAALLIHDMQDYFVS
                     FWGENCPMMEQVIANIAALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRS
                     PEQQKVVDRLTPDADDTVLVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTT
                     ATDAFMRDIKPFMVADALADFSRDEHLMSLKYVAGRSGRVVMTEELLPAPVPASKAAL
                     REVILPLLDESDEPFDDDNLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAW
                     WKLLSREVK"
     gene            complement(9010..10620)
                     /gene="entE"
                     /locus_tag="RHX21_003199"
     CDS             complement(9010..10620)
                     /gene="entE"
                     /locus_tag="RHX21_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2,3-dihydroxybenzoyl)adenylate synthase EntE"
                     /protein_id="HDV1988351.1"
                     /translation="MSIPFTRWPEEFARRYREKGYWQDLPLTDILTRHAASDSIAVID
                     GERQLSYRELNQAADNLACSLRRQGIKPGETALVQLGNVAELYITFFALLKLGVAPVL
                     ALFSHQRSELNAYASQIEPALLIADRQHALFSGDDFLNTFVTEHSSIRVVQLHNDSGE
                     HNLQDAINHPAEDFTATPSPADEVAYFQLSGGTTGTPKLIPRTHNDYYYSVRRSVEIC
                     QFTQQTRYLCAIPAAHNYAMSSPGSLGVFLAGGTVVLAADPSATLCFPLIEKHQVNVT
                     ALVPPAVSLWLQALTEGESRAQLASLKLLQVGGARLSATLAARIPAEIGCQLQQVFGM
                     AEGLVNYTRLDDSAEKIIHTQGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFR
                     GYYKSPQHNASAFDANGFYCSGDLISIDPEGYITVQGREKDQINRGGEKIAAEEIENL
                     LLRHPAVIYAALVSMEDELMGEKSCAYLVVKEPLRAVQVRRFLREQGIAEFKLPDRVE
                     CVDSLPLTAVGKVDKKQLRQWLASRASA"
     gene            complement(10630..11805)
                     /gene="entC"
                     /locus_tag="RHX21_003200"
     CDS             complement(10630..11805)
                     /gene="entC"
                     /locus_tag="RHX21_003200"
                     /EC_number="5.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase EntC"
                     /protein_id="HDV1988352.1"
                     /translation="MDTSLAEEVQQTMATLAPNRFFFMSPYRSFTTSGCFARFDEPAV
                     NGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEK
                     QTSARRFTRSQSLNVVERQAIPEQTTFEQMVARAAALTATPQVDKVVLSRLIDITTDA
                     AIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARR
                     QPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWH
                     LATPFEGKANSQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWC
                     DSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH"
     gene            12180..13136
                     /gene="fepB"
                     /locus_tag="RHX21_003201"
     CDS             12180..13136
                     /gene="fepB"
                     /locus_tag="RHX21_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe2+-enterobactin ABC transporter
                     substrate-binding protein"
                     /protein_id="HDV1988353.1"
                     /translation="MRLAPLYRNALLLTGLLLSGIAAVQAADWPRQITDSRGTHTLES
                     QPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVADDQGFLRQWSKVAKERKLQRLY
                     IGEPSAEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKSWQSLLTQLG
                     EITGHEKQAAERIAQFDKQLAAAKEQIKLPPQPVTAIVYTAAAHSANLWTPESAQGQM
                     LEQLGFTLAKLPAGLNASQSQGKRHDIIQLGGENLAAGLNGESLFLFAGDQKDADAIY
                     ANPLLAHLPAVQNKQVYALGTETFRLDYYSATQVLERLKALF"
     gene            complement(13140..14390)
                     /gene="entS"
                     /locus_tag="RHX21_003202"
     CDS             complement(13140..14390)
                     /gene="entS"
                     /locus_tag="RHX21_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin transporter EntS"
                     /protein_id="HDV1988354.1"
                     /translation="MNKQSWLLNLSLLKTHPAFRAVFLARFISIVSLGLLGVAVPVQI
                     QMMTHSTWQVGLSVTLTGGAMFVGLMVGGVLADRYERKKVILLARGTCGIGFIGLCLN
                     ALLPEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSV
                     ISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPPPPQPREHPLKSLLAGFR
                     FLLASPLVGGIALLGGLLTMASAVRVLYPALADNWQMSAAQIGFLYAAIPLGAAIGAL
                     TSGKLAHSARPGLLMLLSTLGSFLAIGLFGLMPMWILGVVCLALFGWLSAVSSLLQYT
                     MLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGGLGAMMTPVASASASGFGLLIIGV
                     LLLLVLVELRRFRQTPPQVTASDS"
     gene            14501..15505
                     /gene="fepD"
                     /locus_tag="RHX21_003203"
     CDS             14501..15505
                     /gene="fepD"
                     /locus_tag="RHX21_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-siderophore ABC transporter permease"
                     /protein_id="HDV1988355.1"
                     /translation="MSGSVAVTRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEAL
                     SGTCQSADCTIVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGAS
                     FAIVLGAALFGYSSAQEQLAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAA
                     VLEGLTSGIALLNPDVYDQLRFWQAGSLDIRNLHTLKVVLIPVLIAGATALLLSRALN
                     SLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGA
                     DHRWSLPVTLLATPALLLFADIIGRVIVPGELRVSVVSAFIGAPVLIFLVRRKTRGGA
                     "
     gene            15502..16494
                     /gene="fepG"
                     /locus_tag="RHX21_003204"
     CDS             15502..16494
                     /gene="fepG"
                     /locus_tag="RHX21_003204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-enterobactin ABC transporter permease"
                     /protein_id="HDV1988356.1"
                     /translation="MIYVSRRLLITCLLLISACVVAGIWGLRSGAVTLETSQVFAALM
                     GDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWS
                     GVLVAMVLFGQDLTAIALSAMVGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA
                     FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAATLLVRRMRLLE
                     MGDDTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTARW
                     GLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESRKK"
     gene            16491..17306
                     /gene="fepC"
                     /locus_tag="RHX21_003205"
     CDS             16491..17306
                     /gene="fepC"
                     /locus_tag="RHX21_003205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-enterobactin ABC transporter ATP-binding
                     protein"
                     /protein_id="HDV1988357.1"
                     /translation="MTESVARLRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGC
                     GKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLAQNATTPGDITVQELV
                     ARGRYPHQPLFTRWRKEDEEAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQ
                     ETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALR
                     EGKIVAQGAPKEIVTAELIERIYGLRCMIIDDPVAGTPLVVPLGRTAPSTANS"
     gene            complement(17303..18436)
                     /gene="fepE"
                     /locus_tag="RHX21_003206"
     CDS             complement(17303..18436)
                     /gene="fepE"
                     /locus_tag="RHX21_003206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS O-antigen length regulator"
                     /protein_id="HDV1988358.1"
                     /translation="MSSLNIKQGSDAHFPDYPLASPSNNEIDLLNLISVLWRAKKTVM
                     AVVFAFACAGLLISFILPQKWTSAAVVTPPEPVQWQELEKTFTKLRVLDLDIKIDRTE
                     AFNLFIKKFQSVSLLEEYLRSSPYVMDQLKEAKIDELDLHRAIVALSEKMKAVDDNAS
                     KKKDEPSLYTSWTLSFTAPTSKEAQTVLSGYIDYISALVVKESIENVRNKLEIKTQFE
                     KEKLAQDRIKTKNQLDANIQRLNYSLDIANAAGIKKPVYSNGQAVKDDPDFSISLGAD
                     GIERKLEIEKAVTDVAELNGELRNRQYLVEQLTKANINDVNFTPFKYQLSPSLPVKKD
                     GPGKAIIVILSALIGGMVACGSVLLRYAMASRKQDAMMADHLV"
BASE COUNT         4378 a         5265 c         4792 g         4153 t
ORIGIN      
        1 actttcatct atttattcac agcgcgaatg aaaaataaaa cactctgctt tgcagtgttt
       61 actttataat taacagactt atctcactga tcaccctgta acgttcagag agcgtcttca
      121 gatgtctatt tataaaattc ctcttccgct caatattctg gaagctgcac gagagcgtat
      181 tacctggaca ctcaacaccc taccccgcgt ttgtgtctca ttttctggcg gcaaagactc
      241 tggtttaatg ctgcatctga cagccgaact tgcccgacaa atgggcaaaa aaatctgcgt
      301 tttgtttatc gactgggagg cgcaattctc ttgcaccatt aactatgttc agtccctgcg
      361 cgagttgtac accgatgtca tcgaagagtt ttactgggtt gcgctcccgc ttacgacgca
      421 aaattccctt tcacaattcc aacccgaatg gcagtgctgg gaacctgatg tcgaatgggt
      481 gcgtcagccc ccgcaagatg cgataaccga tcctgacttt ttctgctttt accagcctgg
      541 catgaccttc gaacaatttg tacgtgagtt tgccgaatgg ttttcacaaa aacgtccggc
      601 ggcgatgatg atcggcatcc gtgcggatga gtcctacaac cgttttgtcg ccatcgccag
      661 tttaaataaa caacgttttg ccgacgataa accatggact acggccgcac caggcggtca
      721 tagctggtac atttacccca tttacgactg gaaagtggct gatatctgga cctggtatgc
      781 aaatcatcaa agtctctgca acccactgta taacctaatg tatcaggcag gcgttcctct
      841 gcgtcatatg cgaatttgcg aaccttttgg cccggagcaa cgacaaggat tatggctcta
      901 tcacgttatc gaaccggatc gctgggcagc tatgtgcgca cgagtcagcg gggtaaaaag
      961 tggcggcatt tacgccggac atgacaatca tttctatggg catcggaaaa tcctcaagcc
     1021 agaacattta gactggcaag aatatgcatt attgctgctc aatagcatgc cggaaaaaac
     1081 agctgagcat taccgcaata aaatcgccat ttatttgcac tggtatcaga aaaaaggcat
     1141 cgaggttcca caaacccagc aaggggacat tggcgcgaaa gatatcccct cctggcggcg
     1201 gatatgcaaa gttttactca ataacgatta ctggtgtcga gcattatcat ttagtcctac
     1261 gaaagcgaag aactatcagc gttataacga acggataaaa ggaaaacgtc aggaatgggg
     1321 gatactatgc aacaacgatt aacgcaggat ttaacgcaat ttctcgccag cttgccgaaa
     1381 gatgatcgca tcaaagcgat taatgaaatc cgcatggcga tccatcaggt tagccccttt
     1441 cgtgaagagc cagtggattg cgttctgtgg gttaaaaaca gccaacttat gcctaatgat
     1501 tacaacccaa acaacgtggc accacccgaa aaaaaactgc tgaaaaaatc cattgaaata
     1561 gatggtttta cccaacccat tgtggtcacg catacggata aaaatgccct ggaaatcgtg
     1621 gatggttttc accgccatga aattggtaaa ggctcatcat cattaaaatt acgcttaaaa
     1681 ggttatttgc cggtgacctg tctggaaggt acgcgtaatc aacgcatcgc cgcgactatt
     1741 cgtcataatc gcgctcgtgg acgccatcaa atcaccgcca tgtcggaaat cgtccgtgaa
     1801 cttagccagt tgggatggga cgataataaa attggcaaag agctgggaat ggacagcgac
     1861 gaagtgctgc gcctgaagca aattaacggc ctgcaagagc tgtttgccga ccgtcaatat
     1921 tcccgcgcct ggacggttaa ataactaaag ctggcgcagg cgttcagctg ctgccagcaa
     1981 cgtcgattcc ttcttggcaa aacagagacg aatcagttta tgtgggaagg gatcggcgca
     2041 aaacaccgac agcggaatcg ccgctacgcc gtgctcctgc gtcagccact ggcaaaactc
     2101 aacatcatcc agggtagaaa cctcgctgta atccaccagc aaaaagtatg taccttcaca
     2161 cggtaaaatc tccagccggc tttcatttaa agcattcacc agaatatcgc gcttctggcg
     2221 ataaaagtcc ggtaacgcaa gataatgctc aggttctgca cgtagcatat cagcaagcgc
     2281 cagctgtgcc ggggtattca ccgaaaaggt cagatactga tgtaccttgc gaatttcggc
     2341 gctgatgggc gctggcgcaa cacaataacc cactttccag ccggtcatat gataggtctt
     2401 gccaaatgaa gaaaccgcca ctgcccgctc acgcagctgc ggatgcgcca gcacactggc
     2461 atggccctgt tgtgaaaagt tgatgtgctc gtagacttca tcgctaatga caaaaatctc
     2521 gtgcccggcg atcgcctgcc acaaagcggc gaaatcagcc tgctgccaga tagttgcact
     2581 ggggttatgc ggagtgttga ggatcaccag tctggtgcgc tcgcttaata atgcggcaaa
     2641 ttcctgccag tcaacgcgaa aatgcggtgg ttgcagtgcc atacgcttca ctattccccc
     2701 agaaagcgcg atggcggggg agtaactgtc atagctggga tcaaaacaaa tcacttcatc
     2761 gccattgcgc accagtgcgg taatcgccgc gtataacgct tccgtcgccc ctgccgttac
     2821 ggtgatatcg ctatcggcat ctggttgata gccatacaaa cgttccgttt tctgagcaat
     2881 cgcctcgcgc aaggcctgca cgccggtcat gggcgcgtat tggtttgccc cctgggcaac
     2941 gtggtacgcc agccgctcct gtaaatagcg cggaccatca aaatcaggaa agccttgcga
     3001 caggttaatc gcctggtgtt gctgcgccag cgcgctcatc tgggtgaaaa tagtggtgcc
     3061 aagttgtgga agtttgcttt gtggaatcag agggttattt gtcattttta ttgtacctga
     3121 cgaagttgcg tgttgaaggc actataacac gatgctagta tttggcaatc aagacgttta
     3181 gatgtctaaa taaaacaata aggacaacac aacatgcctc acaatcctat ccgcgtggtc
     3241 gtcggcccgg ctaactactt ttcacatcca ggaagtttca atcacctgaa cgattttttc
     3301 actgatgaac aactttctcg cgcggtgtgg atctacggca aacgcgccat tgctgcggcg
     3361 caaaccaaac ttccgccagc gtttggactt ccaggggcaa agcatatttt gtttcgtggt
     3421 cattgcagcg aaagcgatgt acagcaactg gcggctgagt ccggtgacga tcgcagcgtg
     3481 gtgattggcg tcggcggcgg cgcactgctc gacaccgcga aagccctcgc ccgccgtctc
     3541 ggtctgccat ttgttgccgc tccgacgatc gccgccacct gcgcagcctg gacaccgctc
     3601 tccgtctggt ataacgatgc cggacaggcg ctgcattatg agattttcga cgacgccaat
     3661 tttatggtgc tggtggaacc ggagattatc ctcaatgcac cgcaacaata tctgctggcg
     3721 gggatcggtg acacgctggc gaaatggtat gaagcggtgg tgctggctcc gcaaccagaa
     3781 acgttgccgc taaccgtgcg gctggggatc aataatgcgc aggccattcg cgacgtcttg
     3841 ttaaacagta gcgaacaggc acttgccgat cagcaaaatc agcagttaac gcaatcattt
     3901 tgcgatgtgg tggatgcgat tatcgccggg ggtggaatgg tcggtggtct gggcgatcgt
     3961 tttacgcgtg tggctgcggc ccatgccgtg cataacggtc tgactgtcct gccgcaaacc
     4021 gagaaatttc tccacggcac caaagtcgct tacggaattc tggtgcaaag cgccttgctg
     4081 ggtcaggatg atgtgctggc gcaattaacc ggggcgtatc agcgttttca tctgccgact
     4141 acgctggcgg agctggaagt ggatatcaat aatcaggcgg agatcgacaa agtgattgcc
     4201 cacaccttgc gcccggtgga gtccattcat tacctgccag tcacgctgac accagatacg
     4261 ttgcgtgcag cgttcgaaaa agtggaatcg tttaaagcct gacgtgcaaa tttagcagca
     4321 gcgcgcgccg ccttttccac cgtagcgcgc gtcctgccgc tcacggaaaa actcctcgta
     4381 ggtcatcggc gtttgatcgg gatggttaac ccgcatatgt tcgacatagt tgtcgtaatc
     4441 aggcatacca atcatcagct tcgccgcctg acctaaatat tttccggctt ttgccagtga
     4501 atcaaacatc ttggcctccg ctaaccatgt tgctgaaaga gtgccggatg cggcgtgaac
     4561 gctttatccg gcctacaaat gctatcaacg cactcggtca gtcccctcgc cccatcgggg
     4621 agagggttag ggtgaggggg aaccctcggc actatgccaa cattcgccaa catcccccct
     4681 cactctgact ttagtgcgca cctttcgcct gcgctacgat ctcctcaaca ttttccggca
     4741 ttggctcata cggcgtttct ttcgccgttg gcttcggctc tttcaatgcc gcaagtgccg
     4801 tcttaatcga gaacagtgcc agaaccacca cgaccaccat aaagaagatg gttaacccgg
     4861 catccagacg gttgttgaac accagttgcg ccagctgtga ctcagtatac tgcgacggaa
     4921 tattgccgct gtcgatcatt gcctggaact tgttagcaat ggccaggaag ccgactttcg
     4981 catccgggct aaacgctttc tgccagcctg cggtcagggt acaaatcagt agccaggccg
     5041 ttggtaccag cgccacccag gcgtaacgtt gacgtttcat cttgaacaac accacggcac
     5101 agagcatcag cgccatccct gccagcatct ggttggcaat accaaacagc ggccacagag
     5161 tgttaatacc gcccagcgga tcgaccacgc cctgatggag gaagtagccc cacgccagta
     5221 cgcacagcgc cgttgccagc aggttagcag gcagtgaatc ggtccgcttc aggccaggag
     5281 acaccacgcc cagcagatcc tgcaacataa agcgcgcagc acgcgtaccc gcatctaccg
     5341 ccgtcagaat aaacagagct tcaaacagaa tggcgaagtg ataccagaac gccacatcca
     5401 tcataccacc cagcgcaccg tgcaggatgt aagccatccc caccgccaac gtcggcgcac
     5461 cgcccgcacg ggaaatgatc gactgttcac ccacttcgct ggcaatctgg ttgagcgtat
     5521 ctggtgtaat gctaaagccc cagctactca ccacctgcgc ggcagaagcg accacatccg
     5581 ccgtccctgc cggagccagc accgccattg ggctgttcat ggcaaagtaa acgcccggat
     5641 cgatgataca ggcggaaacc agcgccataa tcgccacgaa ggattccatc aacattccac
     5701 cgtagccgat aaaacaagcc tgcccttcgt tcgccagcat cttcggcgtg gtgccggaag
     5761 agatcagcgc atggaagcca gacaccgcgc cacaggcgat ggtgataaac aggaacggga
     5821 acaggttacc ggtccatacc gggccagtgc catcgacaaa tttggtcagc gcaggcatgg
     5881 tcagcgtcgg gcgcataatc aaaatgccta ccgccagacc gacgatcgtc ccgattttca
     5941 ggaaggtaga gaggtagtca cgcggggcca gcagcaacca caccggcagc accgccgcca
     6001 caaaaccgta acccaccagc atccaggtca gctgcacgcc ggtaaagtca aagtacggtg
     6061 cccaggtcgg actttctgcc acccagccgc cagagataat ggcgaaaatc aggaatacca
     6121 gaccgatgac cgacacttca ccaatacgcc ccggacgcag atagcgcagg tagatcccca
     6181 taaacagcgc cagcggaatg gtgaacgcaa cggtatacgt tccccacggg ctatgagtca
     6241 gggctttcac cacgatcatc gccagtactg caaggataat gaccatgatc ataaagcagg
     6301 ccaccagcgc tatcaccccg gcggttggcc ccatctcttc tttgaccagc tcacccagcg
     6361 atcgaccgtc acggcgcgta gaaacaaaca gcaccatgaa atcctgcacc gcaccggcga
     6421 gaaccacccc ggcgagcagc cagatcatcc ctggcaggta acccatttgc gccgccagta
     6481 ccggcccaac caacggacct gctccggcaa tggccgcaaa atggtgacca aacagcactt
     6541 tcttgtccgt cggcacatag tccagcccgt cgttatggcg caccgctggc gtcatacgcg
     6601 tcgggtcaac cgccagcaca tttttggcga tatacagccc ataaaaacgg taagcgatca
     6661 gatagataca gaccgacgcc accacaatcc acagcgcgtt gatctgttcc ccacgattta
     6721 aagcaatgta tcccagagca aatgctccca ttacagagag cactgtccag acgaggtatt
     6781 tccctgattt gttcatagtt gttatccgtg tgcgtgtcca tagatatgtt acattttgtt
     6841 tctataacat ctttgtacga tttaacaaca cggtaaccat gtaaatcgga gttgaaacca
     6901 atatttaact taacaatgtt aactcgatca ctccgttaac cgagttttcc tgcaatctca
     6961 tttaattctg tcgggctcat cccaaaactg ccgtacccag ccgacaagtg cagcaacgcc
     7021 gcccctgttc atcgaaaacg acgatttccc agctctgatt ttgccgccca agatgcagcg
     7081 gctggcagac gccgcgtacc ttgccttcag acaccgggcg atgatgggtg gcgttaagtt
     7141 ccgtacccac cacacactgc ccgtcacggg tcatcataaa tccggccatc gatcccagcg
     7201 tttcagccag cgccgctgac gcgccgccat gcagcaggcc aaacggctga tgagtacggg
     7261 tatcaaccgg catttcggct tccagcacat catctcccag acgggtatac acaattccca
     7321 gatgcgccac cattgtgtta tcgctggtgg cgttcagttc gtcgagcgtt aaatggcgtt
     7381 tccagatcat gcttatgccc ccagcgttga gccgccatcg accacaatat cctgtagggt
     7441 gatatggctg gcgaggtcag aggcgaggaa caaaatcgtg ttggcgatct cttgtggacg
     7501 ggcgattttc cccagcggaa tgccgagttt aaactgctcg ccaaagccgc gaatacgctg
     7561 ttcttcggcg tcatcgctca cccacagcgt gcgttgcata tcggtgtcgg tggagccagg
     7621 cgaaaccaca ttacagcgca cgccgctacc cgccagttcc agcccgacgc tcaacgccag
     7681 gcttttcagc gccgctttcg atgcgccata agcactcatg ccaatacgcg gcgtgtgcgc
     7741 ggcgtcggac gccacagtga caatcgcccc gccccgctga cggcgaaact ggttcatggt
     7801 ttgctggaac aggttaaacg caccgccgac gttaaccgca aaagtctgct gccagtcctc
     7861 tttactgagc tgatcggtcg cgcccatgcg caaaattccc gccgcattga ccagcacgtc
     7921 cagtcgctcc gtttcagcta acagtcgctg acatacctgc gcgacctgcg cagcatcggc
     7981 aacatccatc acttcggtcg caaagggata ttgctcctga gcgaacgctt gatcaaaacc
     8041 ggtaactttc gctcccgcct caacaaacgc cagcgccgtg gcgtagccga tacctttacc
     8101 tgcgccggtt acccagacat ttttaccgct gaaatccatt atttcacctc gcgggagagt
     8161 agcttccacc aggcgtcgat ggtcgggttt ttcgccagca tgacaaagtc gatatcacca
     8221 tgcactttgc gccagcgcgc cgccagcgcc atcatgcgca ccgaatccag accgtagtcg
     8281 atcaggttgt cgtcatcgaa cggttcatcg gactcgtcca gcaacggcag gataacctca
     8341 cgcagcgccg ctttgctggc ggggacaggt gctggcagta attcttcagt catcaccacc
     8401 cggccagacc gcccggccac atatttcagc gacatcaaat gctcgtcacg gctgaaatcg
     8461 gccagcgcat ccgccaccat aaacggttta atatcgcgca taaatgcgtc ggttgcggtg
     8521 gtcatacagc caatgtgggc atataccccg gtaataatca gctggttacg tccactctct
     8581 ttgagcattt gctccagcgg agaacgatga aacgcgctgt agcgccactt caccagcacc
     8641 gtgtcgtcgg catctggcgt caggcgatcc accacctttt gctgttccgg cgaacgggtc
     8701 aggcccggcc cccacatatc attcaacagc gcccgatctt catcgctctg ctctttcggc
     8761 tgggcggtgt aataaaccgg aatattgtgc tgtttgcagt agtcgcgcag cgcagcaata
     8821 ttcgcgatca cctgctccat catcgggcag ttctcgcccc agaagctgac aaaatagtcc
     8881 tgcatatcat ggattaacaa cgcggcacgt tgcggttcaa aggcccagtc aactttattc
     8941 ttagggatat cgtgagactc cggcagtgcg taagcctgta attttggaat agccatcgtg
     9001 ttctctcctt caggctgatg cgcgtgacgc cagccactga cgtaattgtt ttttatcgac
     9061 tttcccgacc gccgtcagcg gaagtgaatc tacacactcc acgcgatccg gtaatttaaa
     9121 ttcggcaata ccctgttcac gcaggaaacg acgcacctgc accgcgcgca gcggctcttt
     9181 taccaccaga taagcgcagc ttttttcgcc catcagctca tcttccatgc tcaccagtgc
     9241 ggcgtagatc accgccgggt ggcgcagcag caggttttcg atctcttcgg cagcgatctt
     9301 ctcaccgcca cggttgatct gatctttctc gcgcccctgc acggtgatgt acccctctgg
     9361 atcaatagag atcagatcgc cggaacagta aaaaccgttg gcatcaaagg cactggcatt
     9421 gtgctgcgga cttttgtaat aaccgcggaa ggtgtacggc ccgcgcgtca tcaggcgtcc
     9481 aacttcccct tgcggcagtg gatttccttc ggcatcggca acccacactt catcgtccgg
     9541 acacattggg taaccctggg tatggataat tttctccgcg ctatcatcaa gacgggtgta
     9601 gttcaccagc ccttccgcca tgccaaacac ctgctgcaac tggcagccaa tctcagcggg
     9661 aatacgcgcc gcaagggtgg cagaaagacg tgcgccgccg acctgtaaca gtttcagcga
     9721 ggcaagctgc gcccggcttt caccttcggt cagcgcctgc aaccacaggc tgactgccgg
     9781 tggcaccagc gcggtgacgt tcacctgatg tttttcaatc aatgggaagc aaagcgtggc
     9841 gctgggatcg gccgccagaa caaccgttcc tccggcaaga aagacgccca gcgatcccgg
     9901 cgaactcatg gcgtagttat gagccgccgg gatcgcgcac aggtagcgtg tctgttgtgt
     9961 gaactgacaa atctcgacgc tacgacgcac gctgtagtag tagtcgttat gagtgcgcgg
    10021 gatcagtttc ggtgtgccgg tggtgccgcc ggaaagctgg aaataggcca cttcatcagc
    10081 aggtgatggc gtggcagtaa aatcctcagc cggatggtta atcgcatcct gcaagttatg
    10141 ctcaccgctg tcgttgtgca gttgcaccac gcgaatggag gaatgttctg tgacgaaagt
    10201 attgaggaaa tcatccccgc taaacagcgc atgttggcga tcggcaatca gcaatgcggg
    10261 ttcaatctgg ctggcatagg cgttcagttc actacgctga tggctgaaca gcgccagcac
    10321 cggcgcaacg cccagtttca gcagcgcgaa aaaggtaata tacaattcag cgacgttacc
    10381 cagttgtacc agcgcggttt caccaggttt aatgccctga cggcgtaaac tacacgcgag
    10441 gttatccgcc gcctgattca gctcccggta actcaactgt cgctcgccgt cgataaccgc
    10501 gatgctgtca ctcgcagcgt ggcgagtcag aatgtcggtc agcggcaaat cctgccagta
    10561 gcctttttcc cgatagcgac gggcaaactc ttccggccag cgggtgaatg gaatgctcat
    10621 cctcgctcct taatgcaatc caaaaacgtt caacatggta gaaagtttga cgcctgtttc
    10681 gcgccactca cccaacggtg acgacgcagg cacaatcccc gctccggcaa acagacgcac
    10741 ctgattttcc cgcagcttcg cgcagcggat ggtcaccacc cattcgccgt taccttcgct
    10801 gtcacaccaa cccacaatgc cgccaaacag ttcgcggtcg aatggctcca gttcagcaat
    10861 aacctgggtc gcggcctgat gcgggaaacc gctcagcgcg ggggttggat gcagcagaca
    10921 ggccagagtc agtgcgtttt cttgcgaatt cgctttacct tcaaagggag ttgcgagatg
    10981 ccacagcgtc ggcgtggtaa tcaattgtgg agaggaggga acgtgtaact cactactgcg
    11041 ttcgcgcagt acctctttca tcgcctgagt caccagttca tgttcatggc gatctttttc
    11101 tgacgccagc agacgattac ccgcttcgcg atcgagcact tcatccggct gacgacgcgc
    11161 ggaaccggct aacggaatgg agctaaaacg ctcgccgtct ttacgtagca gcagttccgg
    11221 gctggccccc agcaggacgc caccatcagc cagcgggaca tggaagttgt aactaaccgg
    11281 gttttgcgca atcaaccgtt ccagcaatac gccactatca atggcggcgt cagtggtgat
    11341 atcaatcaat cgtgacaaca ccactttgtc gacctgcggc gtggcggtaa gtgcggcggc
    11401 gcgggcaacc atctgttcaa acgtggtttg ttcaggaatt gcctggcgtt ccaccacgtt
    11461 cagcgactgg ctgcgggtaa aacggcgggc tgaggtctgt ttttcctggc gggagaacga
    11521 ctgccaggat tcgggaatat acagcgacga aggctgacgt ggatcgaagg gaatcgcccc
    11581 gaccatcacc ggatttttga tgccctgcgc tttggcatcg gcaaacagcg cggcgagttt
    11641 ttgctggaag ggactgtcgg gcgaatcccc gttcacagcc ggttcatcga agcgggcgaa
    11701 acatcctgac gtcgtaaaac tgcggtacgg cgacataaag aaaaagcgat tgggcgcaag
    11761 tgttgccatg gtctgctgta cttcctcagc cagtgacgta tccatatcat cctccacaaa
    11821 atgataaagg ctttaataat gattatcatt tatattttcg gtcgctaacc taaaagcaaa
    11881 cgcgcactat gtcaactctt gaggtaacgc aatctgcaac tcggggttgc atctggttgt
    11941 ggttacaatg aaaatgagaa gcattattga tggattcgca taagcgcaat gtgatgtcct
    12001 gcgccgttct gccccctctc ccttccaggg tgagggctgg ggtgagggtt aatgttcgca
    12061 ccagtgctgg ctgttcccct caccctaacc ctctccccaa aggggcgagg ggacggattg
    12121 tgcgctttgt cgaatttgtc attacgccct taaccttatt aataacagga agctgatttg
    12181 tgagactcgc cccgctctac cgcaacgccc ttctattaac aggactttta ctttcaggaa
    12241 tagccgcagt tcaggccgct gactggccgc gtcagattac tgacagccgt ggcacacata
    12301 cactggaaag ccagccgcag cgtattgttt ccaccagcgt caccctgacc ggctcactgc
    12361 tggcgattga tgctccggtg atcgccagcg gcgcgaccac gccgaataac cgcgtcgcgg
    12421 atgaccaggg ctttttacgc cagtggagca aggtggcgaa agaacgcaaa ctgcaacggc
    12481 tctatatcgg cgaaccgagc gccgaagccg ttgccgcgca aatgccggat ctgattttaa
    12541 ttagcgcaac cggcggggat tcggcgctgg cactgtatga tcagctttcc accatcgccc
    12601 cgacattaat catcaattac gacgacaaaa gctggcagtc gctgttaacg cagcttggcg
    12661 aaattaccgg gcatgagaaa caagcggcag agcggattgc acagtttgat aagcaactgg
    12721 cagcggcgaa agagcaaatc aaattaccgc cgcagccggt cactgccatt gtctataccg
    12781 ccgctgcaca cagtgccaat ctctggacgc cggaatcagc acaagggcag atgctggaac
    12841 aactcggctt tacgctggcg aagttgcccg cagggttaaa cgccagccaa agccagggca
    12901 aacgccatga catcattcag cttggtgggg aaaatctggc tgctgggtta aatggcgagt
    12961 cactattcct gttcgccggt gatcagaaag atgccgatgc gatttatgcc aatccactgc
    13021 tcgcgcacct tcccgcagta caaaacaagc aggtttatgc gctgggaacc gagacgttcc
    13081 gtctggatta ctacagcgcc acgcaagtgc tggaacgact taaggcgctg ttttaagcat
    13141 taactgtcag acgctgtcac ctgcggcggc gtctggcgaa aacgtcgcaa ctccaccagc
    13201 accagcaata acaacacgcc gataatcaac aaaccaaaac cgcttgcgct tgcggaagca
    13261 accggtgtca tcatcgcgcc caaaccaccc agcagcgccg cgcctatggc atcgcccgtc
    13321 acgttctgcg ccgtccacaa accgttaatc cgccctaaca tcgcttccgg ggtttgcgtt
    13381 tgcagcattg tatattgcag caacgaacta accgcgctca gccagccgaa cagcgccaga
    13441 caaaccacgc ctaaaatcca catcggcatc aggccaaaca gaccaatggc gaggaacgat
    13501 cccagcgtgg agagcagcat caataaccct ggtcgcgcac tatgtgccag cttcccgctg
    13561 gttaacgcac caatagccgc gccgagcggg atcgccgcgt agagaaaacc aatctgtgcc
    13621 gctgacatct gccagttgtc agccagcgcc ggatacagta cccgcaccgc gctcgccatc
    13681 gtcaataaac cacccagcag cgcaatcccg cccaccagcg ggctggcaag cagaaaacga
    13741 aatcctgcca gtaatgattt caacggatgc tcacgcggct gcggtggcgg tggcaacgcc
    13801 ggaaggctta acaacggtag caaggtaata aacgtgcccg ccgccgccag cccgtagttc
    13861 caggctacgc caccggtcgc tagcaataaa ccgccaatca tgggcgaaat caccgacccc
    13921 agacgcacgg tcaacatggt gatcgccccg gcctgcatta agttttcacg ccctaccagt
    13981 gctggtgtcg ccgccaatag cgccgtaacg ccaagcgatg cgaaaaaacc atcccataaa
    14041 ccaagtaaat agattgccag caatgacggc tccggcagca gtgcattaag gcacagtcca
    14101 atgaagccaa tgccacaggt gccgcgcgcc agcaaaatca cttttttgcg ctcatagcga
    14161 tccgccagca caccgccaac catcaggcca acaaacatcg cgccgccggt cagcgtcacc
    14221 gaaagcccca cctgccaggt agaatgcgtc atcatctgga tctgcaccgg caccgcgacg
    14281 ccgagcaaac ccagagacac aattgagata aaacgagcga ggaatactgc gcgaaacgcc
    14341 gggtgcgttt tcaacaggct gaggttaagc agccaggatt gtttattcat tacaatgcct
    14401 tgccatcaaa tattttaaat acctattctt aggctgcaca tgctaacata tccaaataag
    14461 atcgataacg ataattaatt tcattatcat ggaagttcgt atgtctggtt ctgttgccgt
    14521 gacacgcgcc attgccgtgc ccggattgct gttattactg attatcgcga cggcattaag
    14581 cctgctcatt ggggcaaaat cactccccgc ttccgtagtg ctggaggccc tctccggcac
    14641 ctgccagagc gccgactgca ccatcgtgct cgacgcgcga ctgccgcgca cccttgccgg
    14701 tttacttgca ggcggcgcgc ttggccttgc cggggcgttg atgcaaaccc tcacccgaaa
    14761 tccacttgcc gaccccggct tgcttggcgt gaatgccgga gccagctttg ccattgtgct
    14821 gggtgcggcg ctgtttggtt actcatccgc gcaggaacaa ctggcgatgg ccttcgccgg
    14881 ggcgctggtg gcctcattga ttgttgcctt taccggcagt cagggcggcg ggcagttaag
    14941 tccggtgcgt ttaaccctgg cgggcgtggc gctggcggcg gtgctggaag gactgaccag
    15001 cggcatcgcc ctgcttaatc ctgacgtcta cgatcaactg cgtttctggc aagccggttc
    15061 gctggatatt cgcaatctac ataccttaaa agtggtgctg atcccggttc tgatcgccgg
    15121 agcaactgcg ctattactga gtcgcgcgct gaacagtttg agcctcggca gtgacaccgc
    15181 gacggcgctg ggcagtcgcg tggcgcgcac acagttaatt ggtctgctgg cgattaccgt
    15241 gctttgtggt agtgcgacag cggtagttgg cccgattgcc tttattggcc tgatgatgcc
    15301 gcatatggcg cgttggctgg tgggtgccga tcatcgctgg tcgctgcccg tcacgctact
    15361 cgccacccct gccctgctgc tgtttgccga tatcatcggg cgggtgattg tgcccggcga
    15421 gttgcgcgtt tctgtggtca gtgcgtttat tggtgcaccg gtgctgatct tcctcgtgcg
    15481 acgtaaaacg cgaggtggtg catgatttac gtctctcgcc gattactcat cacctgtttg
    15541 ctgcttattt ccgcctgtgt ggttgcaggt atctggggat tacgcagcgg tgccgtcacg
    15601 ctggaaacct cgcaggtatt cgccgcgctg atgggcgatg cgccgcgcag tatgacgatg
    15661 gtggtcaccg aatggcgttt accacgcgtg ctgatggcgc tgttgattgg cgcggcactg
    15721 ggcgtcagcg gtgcgatttt tcagtcgctg atgcgtaacc cgctcggcag ccctgacgta
    15781 atgggcttta acaccggggc gtggagcggc gtgctggtgg cgatggtgct gtttggtcag
    15841 gacctgacgg ctatcgcgct gtcagcaatg gtgggcggca ttgtcacttc gcttctggtc
    15901 tggctgctcg cctggcgtaa cggcatcgac acctttcggt tgattattat cggtatcggt
    15961 gttcgcgcca tgctggtggc ctttaatacc tggctgttgc tgaaagcgtc tttagaaacg
    16021 gcgctaacag cgggtttgtg gaatgccgga tcgctcaacg gcctgacgtg ggcaaaaacc
    16081 tcgccttccg cacccatcat tatattgatg ctcattgccg ccaccttgct ggtgcggcga
    16141 atgcgcttgc tggagatggg cgatgatacc gcctgcgcgc tgggcgtcag cgtcgaacgt
    16201 tcgcgtctgt taatgatgct ggttgcagtg gtgcttaccg ctgcggcaac ggcgcttgcc
    16261 gggccgattt cctttattgc tttagtcgcg ccgcacattg cccgacgcat tagcggcacc
    16321 gctcgctggg ggctgaccca ggcggcgctg tgcggagcgc tgttactgct ggcggccgat
    16381 ctctgcgccc aacaactgtt tatgccgtat caacttccgg ttggcgtcgt taccgtcagc
    16441 ctcggcggta tttaccttat cgtcttgtta attcaggagt ctcgcaaaaa atgaccgaat
    16501 cagtagcccg tttgcgcggc gaacagttaa ccctgggata tggcaaatat accgttgcgg
    16561 aaaatctgac tgtagaaatt cctgatggtc acttcacggc aattatcgga ccaaatggct
    16621 gtggtaaatc cacgttactg cgtaccttaa gccgcctgat gacgcctgct cacgggcatg
    16681 tctggctgga tggcgagcac attcaacatt acgccagtaa agaagttgca cgccggattg
    16741 gtctgttggc gcaaaatgct accacgccgg gcgatatcac cgtgcaggag ctggtggcgc
    16801 gtggacgtta tccgcatcaa ccgctgttta cccgctggcg caaagaggat gaagaagcgg
    16861 taacgaaagc gatgcaggcc acgggaataa ctcatctggc agatcaaagc gtggataccc
    16921 tttctggcgg acaacgccag cgcgcgtgga tcgcgatggt gctggcccag gaaacggcaa
    16981 ttatgctgct cgacgaaccc acgacctggc tggatatcag tcatcagatt gatctactgg
    17041 aactgttaag cgaactgaac cgcgagaaag gctataccct ggcggcggtg ctgcacgatc
    17101 ttaatcaggc ctgtcgttac gccagccatt tgattgcatt gcgggaaggg aaaattgttg
    17161 ctcagggagc gccgaaggag attgtcactg ctgaactgat tgagcgcatt tatggtctgc
    17221 gatgcatgat cattgacgat ccggtagccg gaacgccgct tgtggtgccg ctcggacgaa
    17281 cggcaccttc aaccgcaaat agttaaacta agtggtctgc catcatggca tcctgttttc
    17341 tggatgccat cgcatagcgc aataacacgc taccacaagc caccatcccg ccgatcagcg
    17401 cggaaaggat cacaataatc gccttacccg gaccgtcttt tttcactggc aatgacgggc
    17461 ttaactgata tttaaacggc gtaaaattca catcgttgat atttgctttt gttaactgct
    17521 caacaagata ctgacgatta cgtaattcac cgttcagttc cgcaacgtca gtgaccgctt
    17581 tttcaatttc cagtttgcgt tcaataccgt ctgcgccgag agaaatagag aaatcggggt
    17641 catctttaac ggcctgacca ttactgtata cgggcttttt aattcccgcc gcgttggcaa
    17701 tgtcgagtga ataattgagg cgctgaatgt ttgcatcaag ttgatttttc gttttaatgc
    17761 gatcctgagc cagtttttct ttttcaaact gggttttgat ctccagttta ttacggacgt
    17821 tttctatcga ctctttcacc accaacgcag agatataatc gatatacccg ctcaaaacgg
    17881 tctgcgcctc tttactggtt ggcgcggtaa aacttagcgt ccaggaggta tacagtgacg
    17941 gttcatcttt tttcttactg gcattgtcat caaccgcttt cattttttcg ctcaatgcaa
    18001 caatagcgcg atgcaaatcc agttcatcga ttttcgcctc ttttaattgg tccatcacat
    18061 aaggtgatga acgcaggtac tcttccagca agctaaccga ctgaaacttc ttgataaaca
    18121 ggttaaatgc ttctgtacga tcaattttga tatccagatc cagcacacga agcttagtga
    18181 atgttttctc caactcttgc cactgaacag gttctggagg cgtgacaacc gccgcgctgg
    18241 tccatttttg cggcaggatg aaagagatca gcaagcctgc gcaggcaaac gcaaaaacga
    18301 ccgccatgac cgtttttttg gcccgccata aaactgagat tagattaagt aaatcaattt
    18361 cattattact gggcgacgcc agaggataat cgggaaaatg agcgtcactt ccctgtttaa
    18421 tattcagtga tgacatgggg tataacctga aaatgagtcc aataggggga aatctccacg
    18481 gcgctcactt taccagttgg tgagaattat ccgaagctga agtttgtaaa ttccttccaa
    18541 tgaatgcaac attcactcta tttaagagaa ataaccagca aacttata
//
LOCUS       DAPGUL010000085        18333 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.086, whole genome shotgun sequence.
ACCESSION   DAPGUL010000085 DAPGUL010000000
VERSION     DAPGUL010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18333
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.086"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            133..717
                     /locus_tag="RHX21_003207"
     CDS             133..717
                     /locus_tag="RHX21_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV1988359.1"
                     /translation="MSKKLGFALSGLMLAMVAGTASADMDGGQLNISGLVVDNTCETR
                     VDGGNKDGLILLQTATVGEIDAGVLNDTVGAKAKPFSITVDCSKANPNPGSTAKMTFG
                     SVFFGNSKGTLNNDMSINNPSDGVNIALHNIDGSTIKQVQINNPGDVYTKALDATTKS
                     AVYDFKASYVRAVADQTATAGYVKTNTAYTITYQ"
     gene            822..1562
                     /locus_tag="RHX21_003208"
     CDS             822..1562
                     /locus_tag="RHX21_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone"
                     /protein_id="HDV1988360.1"
                     /translation="MFFNTKHTTALCFVTCMAFSSSSIADIVISGTRVIYKSDQKSVN
                     VRLENKGNNPLLVQSWLDTGDDNAEPGSITVPFTATPPVSRIDAKRGQTIKLMYTAST
                     SLPKDRESVFWFNVLEVPPKPDAEKVANQSLLQLAFRTRIKLFYRPDGLKGNPSEAPL
                     ALKWFWSGSEGKASLRVTNPTPYYVSFSSGDLEASGKRYPIDVKMIAPFSDEVMKVTG
                     LNGKASSAKVHFYAINDFGGAIEGNASL"
     gene            1597..4197
                     /gene="htrE"
                     /locus_tag="RHX21_003209"
     CDS             1597..4197
                     /gene="htrE"
                     /locus_tag="RHX21_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Yad fimbria usher protein HtrE"
                     /protein_id="HDV1988361.1"
                     /translation="MTIKPTKNYHNHLTRIATFCALLYCNSAFCAELVEYDHTFLMGQ
                     NASNIDLSRYSEGNPAIPGMYDVSVYVNDQPIINQSITFIEIEGKKNAQACITLKNLL
                     QFHINSPDINNEKAVLLARDETLGNCLNLTEIIPQASVRYDVNEQRLDIDVPQAWVMK
                     NYQNYVDPSLWENGINAAMLSYNLNGYHSETPGRRNDSIYAAFNGGMNLGAWRLRASG
                     NYNWMTDSGSNYDFKNRYIQRDIASLRSQLILGESYTTGETFDSVSIRGIRLYSDSRM
                     LPPTLASFAPIIHGVANTNAKVTITQGGYKIYETTVPPGAFVIDDLSPSGYGSDLIVT
                     VEESDGSKRTFSQPFSSVVQMLRPGVGRWDISGGQVLKDDIQDEPNLFQASYYYGLNN
                     YLTGYTGIQITDNNYTAGLLGLGLNTSVGAFSFDVTHSNVRIPDDKTYQGQSYRVSWN
                     KLFEETSTSLNIAAYRYSTQNYLGLNDALTLIDEVKHPEQDLEPKSMRNYSRMKNQVT
                     VSINQPLKFEKKDYGSFYLSGSWSDYWASGQNRSNYSIGYSNSASWGSYSVSAQRSWN
                     EDGDTDDSVYLSFTIPIEKLLGTEQRTSGFQSIDTQMSSDFKGNNQLNVSSSGYSDNA
                     RLSYSVNTGYTMNKASKDLSYVGGYASYESPWGTLAGSVSANSDNSRQVSLSTDGGFV
                     LHSGGLTFSNDSFSDSDTLAVVQAPGAQGARINYGNSTIDRWGYGVTSALSPYHENRI
                     ALDINDLENDVELKSTSAVAVPRQGSVVFADFETVQGQSAIMNITRSDGKNIPFAADI
                     YDEQGNVIGNVGQGGQAFVRGIEQQGNISIKWLEESKPVSCLAHYQQSSEAEKIAQSI
                     ILNGIRCQIQ"
     gene            4214..4783
                     /locus_tag="RHX21_003210"
     CDS             4214..4783
                     /locus_tag="RHX21_003210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414680.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV1988362.1"
                     /translation="MIKITPHKIAILMGILLSPSVFATDINVEFTATVKATTCNITLT
                     GNNVTNDGNNNYTLRIPKMGLDKIANKTTESQADFKLVASGCSSGISWIDTTLTGNAS
                     SSSPKLIIPQSGDSSSTTSNIGMGFKKRTTDDATFLKPNSAEKIRWSTDEMQPDKGLE
                     MTVALRETDAGQGVPGNFRALATFNFIYQ"
     gene            4798..5400
                     /gene="yadL"
                     /locus_tag="RHX21_003211"
     CDS             4798..5400
                     /gene="yadL"
                     /locus_tag="RHX21_003211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000143198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like protein YadL"
                     /protein_id="HDV1988363.1"
                     /translation="MTFKNLRYGLSSSVVLAASLFSVPSYAATDSIGLTVITTVEIGT
                     CTATLVNDSDQDISVVDFGDVYISEINAKTKVKTFKLKFKDCAGIPNKKAQIKLTKRA
                     TCEGTANDGAGFANGSTAADKASAVAVEVWSTETPATGSATQFSCVTPASQEVTISNA
                     ANAVVYYPMSARLVVEKNKTVSNVTAGKFSAPATFTVTYN"
     gene            5427..6023
                     /locus_tag="RHX21_003212"
     CDS             5427..6023
                     /locus_tag="RHX21_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV1988364.1"
                     /translation="MHPTQRKLMKRIILFLSLQFPITYPAIAGQDIDLVANVKNSTCK
                     SGIINQGNIDLGVVGVGYFSDNVTPESYQPGGKEFTVTVSDCALQGTGDVLNQLHIDF
                     RALSGVMAAGSRQIFANEVATGAKNVGVVLFSIQDPTNIFNVISSAGNSRSVYPVMTS
                     ALHNSSWKFYARMQKIDPALDVISGQVMSHILVDVYYE"
     gene            6076..7350
                     /locus_tag="RHX21_003213"
     CDS             6076..7350
                     /locus_tag="RHX21_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like adhesin"
                     /protein_id="HDV1988365.1"
                     /translation="MKKFFRHFLFLILCLSCYTASAGTDDNVGYIVGNSYGVGPSDQK
                     WRETGPNGDATVIFRYATSTNNLVFYKPTQLGPTGVKLQWSQLDTASGGGFLYCNRSD
                     STSGSAMRIENAMVDSGKMYGSHKLFNTSVPGLYYTLLISNMWSAYGTVTNVSSPGIY
                     IGDSAEQYFSWYNPSEDVLYWSCNNANSTRKYWAVGGIYQTLTIEFYTDTNFDPTVTQ
                     QIKLSSSSNYLYSFKAYGAGQGINEHSYFIKIDFDLLNVKLTNPTCFTAMLSGTSVTG
                     STVKMGEYSAEQIRNGATPVPFDISLQNCVRVTNIETKLVSTKVGTENGQLLGNTLTG
                     NDAAKGVGVLIEGLATSKNPLMTLKPNDSNSVYKDYDPRGKDDTTGGVYPDQDTGITY
                     PLHFQATLQQDGTIPIEAGEFKATSTFQVTYP"
     gene            7463..8257
                     /gene="panB"
                     /locus_tag="RHX21_003214"
     CDS             7463..8257
                     /gene="panB"
                     /locus_tag="RHX21_003214"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HDV1988366.1"
                     /translation="MKPTTIASLQKCKQDKKRFATITAYDYSFAKLFADEGLNVMLVG
                     DSLGMTVQGHDSTLPVTVEDIAYHTAAVRRGAPNCLLLADLPFMAYATPEQAFENAAT
                     VMRAGANMVKIEGGEWLVETVKMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAG
                     DQLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDA
                     FGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH"
     gene            8269..9120
                     /gene="panC"
                     /locus_tag="RHX21_003215"
     CDS             8269..9120
                     /gene="panC"
                     /locus_tag="RHX21_003215"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HDV1988367.1"
                     /translation="MLIIETLPLLRQQIRRLRMEGKRVALVPTMGNLHDGHMKLVDEA
                     KARADVVVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLVFAPSVKEIYPNG
                     TETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGEKDFQQLALIR
                     KMVADMGFDIEIVGVPIMRAKDGLALSSRNGYLTAEQRKIAPGLYKVLSSIADKLQAG
                     ERDLDEIITIAGQELNEKGFRADDIQIRDADTLLEVSETSKRAVILVAAWLGDARLID
                     NKMVELA"
     gene            complement(9194..10096)
                     /gene="rpnC"
                     /locus_tag="RHX21_003216"
     CDS             complement(9194..10096)
                     /gene="rpnC"
                     /locus_tag="RHX21_003216"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-promoting nuclease RpnC"
                     /protein_id="HDV1988368.1"
                     /translation="MDAPSTTPHDAVFKQFLMHAETARDFLEIHLPVELRELCDLNTL
                     HLESGSFIEESLKGHSTDVLYSVQMQGNPGYLHVVIEHQSKPDKKMAFRMMRYSIAAM
                     HRHLEADHDKLPLVVPILFYQGEATPYPLSMCWFDIFYSPELARRVYNSPFPLVDITI
                     TPDDEIMQHRRIAILELLQKHIRQRDLMLLLEQLVTLIDEGYTSGSQLVAMQNYMLQR
                     GHTEQADLFYGVLRDRETGGESMMTLAQWFEEKGIEKGIQQGRQEERQEFALRLLSKG
                     MSREDVAEMTNLSLAEIDKVINLI"
     gene            10370..10750
                     /gene="panD"
                     /locus_tag="RHX21_003217"
     CDS             10370..10750
                     /gene="panD"
                     /locus_tag="RHX21_003217"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HDV1988369.1"
                     /translation="MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAI
                     DIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWR
                     PNVAYFEGDNEMKRTAKAIPVQVA"
     gene            complement(10754..11983)
                     /locus_tag="RHX21_003218"
     CDS             complement(10754..11983)
                     /locus_tag="RHX21_003218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDV1988370.1"
                     /translation="MYKQAVILLLMLFTASVSAALPARYMQTIENAAIWAQIGDKMVT
                     VGNIRAGQIIAVEPTAASYYAFNFGFGKGFIDKGHLEPVQGRQKVEDGLGDLNKPLSN
                     QNLITWKDTPVYNAPSAGSAPFGVLADNLRYPILHKLKDRLNQTWYQIRIGDRLAYIS
                     TLDAQPDNGLPVLTYHHILRDEENTRFRHTSTTTSVRAFNNQMAWLRDRGYATLSMAQ
                     LEGYVKNKINLPARAVVITFDDGLKSVSRYAYPVLKQYGMKATAFVVTSRIKRHPQKW
                     NPKSLQFMSVSELNEIRDVLDFQSHTHFLHRVDGYRRPILLSRSEHNILFDFARSRRA
                     LAQFNPHVWYLSYPFGGFNDKAVKAANDAGFHLAVTTMKGKVKPGDNPLLLKRLYILR
                     TDSLETMSRLVSNQPQG"
     gene            complement(12047..12487)
                     /locus_tag="RHX21_003219"
     CDS             complement(12047..12487)
                     /locus_tag="RHX21_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDV1988371.1"
                     /translation="MLGWVITCHDDRAQEILDALEKKHGALLQCRAVNFWRGLSSNML
                     SRMMCDALHEADSGEGVIFLTDIAGAPPYRVASLLSHKHSRCEVISGVTLPLIEQMMA
                     CRETMTSSEFRERIVELGGPEVSSLWHQQQKNPPFVLKHNLYEY"
     gene            complement(12592..13362)
                     /locus_tag="RHX21_003220"
     CDS             complement(12592..13362)
                     /locus_tag="RHX21_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001747261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV1988372.1"
                     /translation="MMHLYWVALKSIWAKEIHRFMRIWVQTLVPPVITMTLYFIIFGN
                     LIGSRIGDMHGFSYMQFIVPGLIMMSVITNAYANVASSFFGAKFQRNIEELLVAPVPT
                     HVIIAGYVGGGVARGLFVGILVTAISLFFVPFQVHSWVFVALTLVLTAVLFSLAGLLN
                     GVFAKTFDDISLVPTFVLTPLTYLGGVFYSLTLLPPFWQGLSHLNPIVYMISGFRYGF
                     LGINDVPLVTTFGVLVVFIVAFYLICWSLIQRGRGLRS"
     gene            complement(13359..14285)
                     /locus_tag="RHX21_003221"
     CDS             complement(13359..14285)
                     /locus_tag="RHX21_003221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDV1988373.1"
                     /translation="MTIALELQQLKKTYPGGVQALRGIDLQVEAGDFYALLGPNGAGK
                     STTIGIISSLVNKTSGRVSVFGYDLEKDVVNAKRQLGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVERKEAYIRSEKYLKQLDLWGKRNERARMLSGGMKRRLMIARALMHEPKLLIL
                     DEPTAGVDIELRRSMWGFLKDLNDKGTTIILTTHYLEEAEMLCRNIGIIQHGELVENT
                     SMKALLAKLKSETFILDLAPKSPLPKLDGYQYRLVDTATLEVEVLREQGINSVFTQLS
                     EQGIQVLSMRNKANRLEELFVSLVNEKQGDRA"
     gene            14394..15056
                     /gene="can"
                     /locus_tag="RHX21_003222"
     CDS             14394..15056
                     /gene="can"
                     /locus_tag="RHX21_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonate dehydratase"
                     /protein_id="HDV1988374.1"
                     /translation="MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSD
                     SRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEVEHIIICGHYGCG
                     GVQAAVENPELGLINNWLLHIRDIWFKHSSLLGEMPQERRLDTLCELNVMEQVYNLGH
                     STIMQSAWKRGQKVTIHGWAYGIHDGLLRDLDVTATNRETLEQRYRHGISNLKLKHAN
                     HK"
     gene            complement(15097..15633)
                     /gene="hpt"
                     /locus_tag="RHX21_003223"
     CDS             complement(15097..15633)
                     /gene="hpt"
                     /locus_tag="RHX21_003223"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004204384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDV1988375.1"
                     /translation="MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRG
                     SFMFMADLCREVQVSHEVDFMTASSYGSGMSTTRDVKILKDLDEDIRGKDVLIVEDII
                     DSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDY
                     AQRYRHLPYIGKVILLDE"
     gene            15839..18229
                     /gene="gcd"
                     /locus_tag="RHX21_003224"
     CDS             15839..18229
                     /gene="gcd"
                     /locus_tag="RHX21_003224"
                     /EC_number="1.1.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinoprotein glucose dehydrogenase"
                     /protein_id="HDV1988376.1"
                     /translation="MAINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYP
                     IAGLVMLGVAWMLWRSKRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGI
                     WLILPFVWRRLVIPASGAVAALVVALLISGGILTWAGFNDPQEINGTLSANATPAEAI
                     SPVADQDWPAYGRNQEGQRFSPLKQINADNVHNLKEAWVFRTGDVKQPNDPGEITNEV
                     TPIKVGDTLYLCTAHQRLFALDAASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAE
                     TASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLNLQSNMPDTKPGLYE
                     PTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSD
                     EHTFTFNSPNSWAPAAYDAKLDLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATT
                     GKLAWSYQTVHHDLWDMDLPAQPTLADITVNGQKVPVIYAPAKTGNIFVLDRRNGELV
                     VPAPEKPVPQGAAKGDYVTPTQPFSELSFRPKKDLSGADMWGATMFDQLVCRVMFHQL
                     RYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGN
                     PMEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEV
                     VWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAGNVLFIAATADNYLRAYNMSN
                     GEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK"
BASE COUNT         4939 a         4413 c         4306 g         4675 t
ORIGIN      
        1 acaatggttg taaattttgg taacaaatat cattgctcat taatatctag catctgctta
       61 taacatttgt gtcatgaata gtcattcttc aaaccagtag tctgactaat ggaattttat
      121 tcaaggattt ttatgtctaa aaaattaggt tttgccctgt ctggtcttat gctggcaatg
      181 gttgcaggta ctgcttctgc tgatatggat ggtggtcagt taaatatcag tggtctggtt
      241 gttgataaca cctgtgaaac ccgcgttgac ggcggtaata aagatggtct gatcctgctg
      301 caaactgcaa ctgttggtga aatcgatgct ggcgtgctga atgacaccgt tggcgctaaa
      361 gccaaacctt tcagcatcac cgttgactgc agcaaagcaa atccgaatcc aggtagtaca
      421 gctaaaatga ccttcggttc tgttttcttt ggtaatagca aaggaacgct gaacaacgac
      481 atgtctatta acaacccgtc tgacggcgtg aatatcgctc tgcacaatat tgatggttcc
      541 actatcaaac aggttcaaat taacaaccct ggcgatgtgt atactaaagc cctggatgca
      601 acgacaaaat ctgctgttta tgattttaaa gcgtcttacg ttcgtgccgt cgcagaccaa
      661 acagcaactg ctggttatgt aaaaactaac actgcataca ccattactta tcagtaagta
      721 ttcaccaatt aaattgattg aatgaatata cagggaatag tgttaataat ttctattttt
      781 atattattcc ctgttttaat taactctgtc agggatggtt tatgtttttt aacaccaaac
      841 atacaacagc tttatgcttc gtaacctgta tggcttttag ttcatcgtct attgcggaca
      901 ttgtcatttc gggtactcgc gtaatatata aaagcgatca aaaaagtgtc aacgtacgtc
      961 tggaaaataa agggaataac ccgttgcttg tccagagttg gttagatact ggcgatgaca
     1021 acgctgagcc tggcagtatt acagtccctt ttactgccac gccgccagta tcgcgtattg
     1081 atgccaaacg tgggcaaaca atcaaattaa tgtacacagc cagcacctca ctgcctaaag
     1141 acagagagag cgtgttctgg tttaacgtac tggaagttcc accaaaacca gatgcagaaa
     1201 aggtcgcgaa tcaaagtctg ctgcaactgg catttcgcac acgtataaaa cttttctatc
     1261 gcccggatgg attgaaggga aatccctctg aagccccgtt agccctgaag tggttctggt
     1321 caggttcaga aggtaaggcg tcattgcgag tgaccaatcc aaccccttac tacgtctctt
     1381 ttagcagtgg tgatttagaa gctagcggta aacgctatcc gattgatgtg aaaatgattg
     1441 caccatttag tgatgaggtc atgaaagtca ctggccttaa tggcaaagca agttctgcaa
     1501 aagtacattt ttacgccatt aatgattttg gtggcgccat tgaaggtaat gccagtctgt
     1561 aatcaggcaa ggatataatt ccgcaggaag cataacgtga ctataaaacc aactaaaaat
     1621 tatcataatc atctgacccg tatcgctacg ttttgcgcgc tgctgtattg caatagtgct
     1681 ttctgtgctg aacttgttga atatgaccat accttcctga tggggcagaa tgcctcaaat
     1741 attgatctca gccggtatag tgaaggtaac cctgctatac cgggtatgta cgacgtcagt
     1801 gtttatgtca acgatcaacc tattattaac caaagcatta catttattga aattgaagga
     1861 aaaaaaaacg cacaagcctg tatcacactt aagaatttat tgcagtttca tataaattct
     1921 cccgatataa ataacgaaaa agccgttctg cttgccaggg atgaaacact cggcaattgc
     1981 cttaatttga cggaaattat ccctcaggct tctgttcgtt atgacgttaa cgagcaacgt
     2041 ctggatatag acgttcctca ggcatgggta atgaaaaatt accaaaacta tgttgatcca
     2101 tcgttatggg aaaatggcat taatgcggcc atgttgtcat acaacctcaa cggatatcat
     2161 agtgaaactc ctggtcgaag aaatgacagc atttatgctg cttttaacgg tgggatgaat
     2221 ttaggtgcat ggcgactgcg tgcctcaggc aactacaact ggatgaccga ttctggcagt
     2281 aattatgatt ttaagaatcg gtatatacag cgtgatatcg cctcgctgcg ttctcaactc
     2341 attcttggtg agtcttatac aacgggcgaa acctttgatt ctgtcagtat acgcggcatt
     2401 cgtttataca gcgacagccg catgttgcct ccgacattag cgagttttgc gcctatcatt
     2461 catggcgttg ctaataccaa cgccaaagtc actattacgc aaggtggcta taagatttat
     2521 gaaacgactg tgccgccagg cgctttcgtc attgatgatc tgagtccgtc aggttacggc
     2581 agcgatctta ttgttactgt cgaagaatcc gatggctcaa agcggacatt ctcgcaacct
     2641 ttttcatcgg tcgttcaaat gttacgccct ggcgttggac gttgggatat tagcggcggc
     2701 caggtcttaa aagatgatat tcaggatgag cctaatttat ttcaggccag ctactactac
     2761 ggtctgaata actatctaac gggttatact ggtattcaga ttaccgataa taactatacc
     2821 gctggtttgt taggtcttgg tctgaatact tcagtcggtg cattttcttt cgatgtgact
     2881 cactccaatg ttcgtatacc ggatgataaa acatatcagg gacaaagtta tcgtgtttcc
     2941 tggaacaagt tattcgaaga aacaagtact tcactgaata tcgcggccta tcgctattcg
     3001 acacagaatt accttggtct taatgatgca ctaactctaa ttgatgaagt gaaacatccc
     3061 gaacaagatc ttgaaccgaa atccatgcgt aattactcgc gcatgaaaaa tcaggttacg
     3121 gtcagtatta accaaccgct aaaatttgag aaaaaagatt acggttcatt ttatctttcc
     3181 ggaagttggt ccgattactg ggcttccgga caaaatcgta gcaattactc tattggctac
     3241 agtaacagtg catcctgggg cagctacagt gtcagtgccc agcgttcatg gaatgaagac
     3301 ggcgacactg acgatagcgt ttatctcagt ttcaccattc ctattgaaaa attacttggc
     3361 actgaacaac ggacttcagg tttccagagt attgatactc aaatgagcag tgactttaag
     3421 ggtaataacc aactcaacgt cagtagcagt ggctatagtg ataacgctcg cctcagttat
     3481 agcgtaaata ctggctatac gatgaataaa gccagcaaag atttgagtta tgttgggggt
     3541 tatgccagct atgaatcacc gtggggaacc ctggcaggtt cagtttctgc aaatagcgat
     3601 aacagtcgtc aagtgtctct cagcaccgac ggtggttttg tattgcatag cggcggcctg
     3661 accttcagta atgacagttt tagcgactcc gatacactgg cggtagttca ggctccaggt
     3721 gctcaaggag cgcgaataaa ttatggcaac agtactatcg atcgatgggg ttatggtgtc
     3781 accagcgctc tttctcctta tcatgaaaac cgtatcgcgc tggatatcaa cgatcttgag
     3841 aacgatgttg aattaaaaag taccagtgca gtagctgtac cgcgtcaggg ttcagtcgtc
     3901 tttgctgatt ttgaaaccgt gcaagggcaa tcagccatta tgaacatcac acgaagtgat
     3961 ggtaaaaata ttccatttgc tgcagatatt tatgatgagc aaggcaatgt cattggtaat
     4021 gttggacagg gtggacaagc atttgttcgt ggtattgagc agcagggaaa tatcagcatt
     4081 aaatggctcg aagaaagtaa acccgtaagt tgtcttgcgc attatcaaca aagttcagaa
     4141 gcagaaaaaa tagcgcaatc tattattctg aatggaattc ggtgtcagat tcagtaacta
     4201 caagggacgt caaatgataa aaataacgcc acataaaata gcgatactga tgggaatatt
     4261 attatcacca tcagtatttg caacggatat taatgtagag tttacagcca ctgtcaaagc
     4321 gacaacctgt aacatcacac ttactggtaa taacgtcacg aatgatggca ataataacta
     4381 cacattgaga atccctaaga tgggtctgga taagatcgcg aataaaacga cagaatctca
     4441 ggctgatttt aaactggttg ctagtgggtg cagcagtggc atcagttgga ttgataccac
     4501 tctgaccgga aatgcatcat caagctcacc taagcttatt ataccgcagt ctggtgattc
     4561 atcttcgacg acaagtaata tcggtatggg tttcaaaaaa cggactactg atgatgccac
     4621 tttccttaaa cctaacagtg cggaaaagat acgctggagc acagacgaga tgcagcccga
     4681 taagggtctt gaaatgaccg ttgcgctacg tgaaacagat gcagggcaag gcgtaccggg
     4741 gaattttcgt gcactggcaa cgtttaattt catctatcaa taagaaggat aattaagatg
     4801 acatttaaaa atttacgtta tggattatcc agcagtgtcg ttttggctgc ctcattgttc
     4861 agcgtaccct cttatgcggc aacagacagc attgggctga ccgtgattac taccgtagaa
     4921 ataggtactt gtactgctac attagtaaat gactctgatc aggacatttc tgttgttgac
     4981 tttggcgatg tatatatttc tgaaatcaat gccaagacca aagttaaaac attcaaactc
     5041 aaattcaaag actgtgcggg tatccccaat aaaaaagcac aaataaaatt aaccaagcga
     5101 gccacatgcg aaggtactgc taatgacggt gcggggttcg caaatggatc cacagccgca
     5161 gataaagcaa gtgccgtcgc cgttgaagtc tggagcaccg aaactccggc aacagggagc
     5221 gcaacacaat ttagttgtgt gacaccagca tctcaagagg tcactatctc caatgcagcc
     5281 aacgcggttg tttattatcc gatgagtgct cgactggtcg tcgaaaaaaa taaaaccgta
     5341 agcaatgtca ctgcgggtaa attttctgca cctgccacat ttacagtaac ctataactaa
     5401 cagactgaca gatccaggaa ctatatatgc atcccactca acgtaagctg atgaagagaa
     5461 taattctgtt tctgtcacta cagtttccca ttacctatcc agccatcgct gggcaggata
     5521 ttgaccttgt tgccaatgta aaaaacagca cttgcaaaag cggaatcatt aaccagggta
     5581 atattgatct tggcgtcgtt ggggtgggat atttttcaga taatgttact cctgaaagct
     5641 atcaaccagg tggaaaagag ttcactgtca cagtatcaga ctgtgcatta cagggaactg
     5701 gcgatgtgct taatcagtta catattgatt ttagagccct tagcggtgtc atggctgcag
     5761 gttcaaggca aatatttgcc aatgaagtcg caaccggggc taaaaatgtc ggtgtcgttc
     5821 tcttttccat tcaggacccg accaatatat tcaatgttat tagttcagca ggaaattctc
     5881 gttccgtgta tccagtaatg acttctgccc tgcataattc ttcatggaaa ttttatgcca
     5941 gaatgcaaaa aatcgatccc gcgctggatg tcatatctgg ccaggtaatg agtcatatat
     6001 tagttgatgt gtactacgaa taatagatca aaacaaataa ctgcgactgt tacagcagta
     6061 gatggtggag tgataatgaa gaaattcttc agacattttc tttttttaat tctgtgcttg
     6121 agttgttata ccgcgagtgc tggcactgat gataacgtag gatatattgt tgggaatagt
     6181 tacggcgttg gtccgtcaga tcaaaaatgg agagaaacgg ggccgaatgg cgatgctact
     6241 gtcatattca gatatgcaac aagtacaaat aatttagttt tctacaaacc gacgcagctt
     6301 ggacctacag gtgtaaaatt acagtggagt cagttagata ccgcttctgg tggtggtttt
     6361 ctttattgca acagaagtga tagcacaagt ggtagcgcaa tgcgtattga aaatgcaatg
     6421 gttgactcag gtaaaatgta tggctcccat aaattattta atacatcagt tcctggtttg
     6481 tattacacat tattaatttc aaacatgtgg tcagcttacg gtaccgtaac taacgttagt
     6541 tcacctggga tatacattgg tgactctgca gaacaatatt tttcgtggta taatccaagc
     6601 gaagacgtgt tatattggag ttgcaataat gcgaatagca cccgtaaata ctgggctgta
     6661 ggtggtattt atcagaccct tacaattgaa ttctatacag atacaaactt tgatccaaca
     6721 gtaactcaac agatcaaatt atccagctca tcaaattatc tgtattcatt taaagcctat
     6781 ggcgcaggcc aaggtataaa tgagcatagt tattttatca aaatcgattt cgatctgctc
     6841 aatgtcaagt tgactaatcc cacttgtttt accgctatgc ttagtggaac ttctgtgact
     6901 ggttctacgg taaaaatggg tgaatatagt gcagaacaaa tcagaaacgg tgccacaccg
     6961 gttccttttg atatttcact tcaaaactgc gttcgtgtga ctaatattga gacaaaatta
     7021 gtttcaacaa aggttggtac tgaaaacggg caactccttg gtaatactct cacaggtaat
     7081 gacgcagcaa aaggagtcgg tgtactcata gaaggtttag caactagtaa aaatcctcta
     7141 atgacattga aacctaatga ttcaaattct gtttataaag attacgaccc gagaggcaaa
     7201 gacgatacaa caggaggagt ttacccggat caagatacag gtataacata ccctctccat
     7261 ttccaggcca cgctacaaca ggatggaact ataccaatag aagctggtga gtttaaagcc
     7321 accagtactt tccaggtaac ctacccttaa taagtccacc gcaccgccat catctggcgg
     7381 tgcggtaatt gataaatcat tgcccccacc aatgtgactg ataaaatgcc aggcaacacg
     7441 acatcattta tcaggacacg ttatgaaacc gaccaccatt gcttcacttc agaaatgtaa
     7501 gcaggataaa aagcgtttcg cgaccatcac cgcttacgac tacagcttcg cgaaactatt
     7561 tgctgatgaa ggacttaacg tcatgctggt aggcgattcg ctgggcatga cggttcaggg
     7621 ccacgactcc acccttcccg ttaccgtcga ggatatcgcc taccacactg ccgccgtacg
     7681 tcgcggcgcg ccaaactgcc tgctgttggc tgacctgccg tttatggcgt atgccacgcc
     7741 ggaacaagcc tttgaaaacg ccgcaacggt tatgcgtgcc ggtgccaata tggtcaaaat
     7801 tgagggcggt gagtggctgg tcgaaaccgt aaaaatgctg accgaacgtg ccgttcctgt
     7861 atgtggtcac ttaggtttaa ccccacagtc agtgaatatt ttcggtggct acaaagttca
     7921 ggggcgcggc gatgaagcgg gcgatcaact gctcagcgat gcattagcct tagaagccgc
     7981 tggggcacag ctgctggtgc tggaatgcgt gccggttgaa ctggcaaaac gtattaccga
     8041 agcactggcg atcccggtta ttggcattgg cgcaggcaac gtcactgacg ggcagatcct
     8101 cgtgatgcac gacgccttcg gcattaccgg cggtcacatt cctaaattcg ctaaaaattt
     8161 cctcgccgaa acgggcgaca tccgcgcggc tgtgcggcag tatatggctg aagtggagtc
     8221 cggcgtttat ccgggcgaag aacacagttt ccattaagga gtcacgttgt gttaattatc
     8281 gaaaccctgc cgctgctgcg tcagcaaatt cgccgcctgc gtatggaagg caagcgcgtg
     8341 gcgctggtgc ctactatggg taatctgcac gatggccata tgaagctggt cgacgaagcc
     8401 aaagcccgcg ccgatgtggt cgtcgtcagt attttcgtta acccgatgca gttcgaccgc
     8461 ccggaagatc tggcacgtta tccacggacc ttgcaggagg actgcgagaa gctaaacaaa
     8521 cgtaaagtgg atttagtttt cgccccttcg gtaaaagaga tctacccgaa cggtactgaa
     8581 acccatactt acgttgacgt tcccgggctt tcgaccatgc tggaaggcgc gagccgtccg
     8641 gggcattttc gcggcgtttc gactatcgtc agcaagctgt ttaacctggt ccagccggac
     8701 atcgcctgct tcggtgaaaa ggactttcag caactggcgc tgatccgcaa aatggttgcc
     8761 gatatgggct tcgatattga gattgtcggt gtgccaatta tgcgcgccaa agacggtctg
     8821 gcgctaagtt cccgtaacgg ttatctgacg gcggaacaac gcaaaattgc gcctggtctg
     8881 tacaaagttt taagttcgat tgctgacaaa ttgcaggctg gggaacggga tctcgatgaa
     8941 attattacca ttgcggggca agaactgaat gaaaaaggct tccgcgccga tgatattcag
     9001 attcgcgatg ccgacacatt gctggaagtt tctgaaacca gcaaacgggc agtaattctg
     9061 gtagccgcct ggcttggcga tgctcgcctg atcgacaaca aaatggtcga gctggcgtaa
     9121 tacttaactg gcgctacggc tgatggcgcc agttattaat ttaccccacg tcatctgtca
     9181 taacacaggt aacttaaata aggttaatta ccttatcaat ctcagcaaga gataaatttg
     9241 tcatctctgc aacgtcttcc cgagacattc ctttacttag aagacgcagg gcgaattctt
     9301 gcctttcctc ctgtcttccc tgctgaatcc ccttctcaat ccctttctct tcaaaccact
     9361 gcgccagcgt catcatagac tcccctcccg tttccctgtc tctcagcaca ccataaaaca
     9421 aatccgcttg ttcagtatga ccgcgttgca gcatatagtt ttgcatggca actaactgac
     9481 ttccgctagt gtacccttcg tcaatcagcg tgaccagttg ctccagcaat aacattaagt
     9541 cgcgctggcg aatatgtttt tgcagtagtt cgagaatcgc aatccgccga tgttgcatga
     9601 tttcgtcatc cggtgtgatg gtgatatcca ccagcgggaa aggactgtta tagacgcgtc
     9661 gtgccagctc cggcgagtaa aatatatcaa accagcacat tgagagcgga taaggtgtgg
     9721 cctcgccctg ataaaacagt atcggcacca ccagcggcag cttatcgtga tccgcctcca
     9781 gatgccggtg catggcagca atagaataac gcatcatgcg aaaggccatt ttcttatccg
     9841 gcttgctttg gtgttcaatc acaacatgca gataaccggg attgccctgc atttgcacgg
     9901 aatagagcac gtccgtgctg tgtcctttca ggctctcttc aatgaaactc cccgactcta
     9961 aatgaagcgt gttgaggtca caaagttctc gtaattccac tggcaaatgt atctccagaa
    10021 agtcgcgagc cgtctccgca tgcattaaaa attgtttaaa taccgcgtca tgcggtgtgg
    10081 tactcggtgc atccatcttc cctgtcttcc gtgttgtctt gcgtgaaggc agtatccagt
    10141 caaggcgcgc cgtcgtcagc cgcctcttta gtgtttaccg agcagcgttc agagaaattt
    10201 caattcgtta caggcgatac atggcacgct tcggcgcggt acgcaaactg ctgacgcaaa
    10261 tgccatcaga tgagtagaca ctcatcaaaa atcgggcaat actgcgtgag aatttcctca
    10321 aagcaggcac cgcctgcttc gttaacgaca gggtagaaag gtagaagtta tgattcgcac
    10381 gatgctgcag ggcaaactcc accgcgtgaa agtgactcat gcggacctgc actatgaagg
    10441 ttcttgcgcc attgaccagg attttcttga cgcagccggt attctcgaaa acgaagccat
    10501 cgatatctgg aatgtcacca acggcaagcg tttctccact tatgccatcg cggcagaacg
    10561 cggttcgaga attatttctg ttaacggtgc ggcggcccac tgcgccagcg tcggcgatat
    10621 tgtcatcatc gccagcttcg ttaccatgcc agatgaagaa gctcgcacct ggcgacccaa
    10681 tgtcgcctat tttgaaggcg acaatgaaat gaaacgtacc gcgaaagcga ttccggtaca
    10741 ggttgcttga ttgttatccc tgcggctggt tactcaccag ccgcgacatc gtctccagcg
    10801 aatccgttct taagatataa agtcgtttta gtaacaacgg attatccccc ggttttactt
    10861 tgcctttcat ggttgtcacc gccaggtgaa atccggcatc gtttgctgcc ttcacggctt
    10921 tgtcattaaa tccgccaaac ggatacgaaa gataccagac atgcggatta aattgcgcca
    10981 gagcgcggcg tgaacgtgca aaatcaaaca gaatattgtg ctcactacgg ctcagtaata
    11041 tgggtcggcg atagccatcc acccgatgca aaaaatgggt atgtgactga aaatcaagaa
    11101 catcgcgaat ttcgttaagc tcagaaacgc tcataaattg cagcgatttt gggttccact
    11161 tctgcgggtg acgtttgatg cgcgaggtaa caacaaacgc cgtcgccttc atgccatatt
    11221 gtttcaatac aggatacgca tagcggctca ccgacttgag gccatcatca aaggtaatca
    11281 ccaccgctcg cgcagggaga ttgatcttat tcttcacgta accttccagc tgcgccatgc
    11341 tcagtgtcgc gtatcccctg tcgcgcagcc aggccatctg gttattgaaa gcgcgtaccg
    11401 aggtggtcgt cgaagtatgg cgaaaacggg tgttttcttc atcgcgcaga atatggtgat
    11461 aggttagcac cggcaggcca ttatcgggtt gggcatccag cgtgctgata taggcgagtc
    11521 gatcgccaat acggatctga taccaggttt gatttaacct gtctttcagt ttatgcaaaa
    11581 tcgggtagcg caaattgtcc gccagtaccc caaatggcgc actgcccgca ctcggcgcgt
    11641 tatagaccgg cgtatctttc caggtaatta agttctgatt actcagcggc ttgttgaggt
    11701 cacccaaacc gtcttcaact ttttgtcgcc cctgaactgg ctcgagatgc cctttatcga
    11761 taaacccttt accaaagcca aaattaaatg cgtaataact tgcggcagtg ggctccacgg
    11821 caatgatttg cccggcccga atattcccca cggtcaccat cttgtcgcca atttgcgccc
    11881 agatcgcagc attttcgatg gtttgcatat aacgggcagg taacgcggca ctgacacttg
    11941 cggtaaacag catcagcagg agaataacag cttgtttgta catgaaaaaa taaccgaggg
    12001 tgaaacaacg cttttattgt agcaaaagcg ctataagaat cgtgggttaa tactcataca
    12061 aattatgttt gaggacgaaa ggcggatttt tttgttgttg gtgccaaaga ctactcacct
    12121 ccggcccacc cagttcgaca atacgctcgc gaaactctga actggtcatg gtttcacggc
    12181 aagccatcat ctgttcaatt aacggtaacg tgacaccaga aatcacttcg caacgggagt
    12241 gtttgtggct taataatgaa gccacgcggt acggtggcgc tccggctata tcggttaaga
    12301 agatgacacc ctcaccagag tccgcttcat gcagagcatc gcacatcatg cggctgagca
    12361 tattagagct taacccacgc cagaaattca cggcccggca ctgaagaagc gccccatgtt
    12421 ttttctccag cgcatccagt atctcttgcg cccggtcatc gtgacaggta attacccaac
    12481 ctaacatcgc cttcctcctt agccgaaaat cagtctaccc tgaccattgt tgataaaggg
    12541 tgatagccgt caaaactcct ctcccccaaa tccagaggag aggaaatagc cttagctacg
    12601 caaaccacgt ccacgttgga tcagcgacca acagatcaaa taaaacgcca caataaagac
    12661 caccagtacg ccaaaagtag tgaccagcgg aacatcattg ataccgagga agccgtagcg
    12721 gaaaccactg atcatataaa cgattgggtt caggtgcgac agcccttgcc agaacggcgg
    12781 caacaaagtc agtgagtaaa agaccccacc caaatacgtg agtggcgtta acacaaaggt
    12841 tggcaccagg ctgatgtcat cgaacgtttt ggcaaacaca ccgttcagca aacccgcaag
    12901 ggagaacaac accgccgtga gcaccagggt taaggcaacg aatacccacg aatgcacctg
    12961 aaacggcaca aaaaacagtg aaattgccgt caccagaatg ccaacaaaca gaccacgcgc
    13021 cacgccaccg ccgacatatc cggcaataat gacgtgagtc ggaaccggcg ctaccagcag
    13081 ctcttcaata ttacgctgga acttggcacc aaaaaatgat gacgcaacgt tggcgtaggc
    13141 attggtgatc accgacatca tgatcagccc cggtacgatg aactgcatat agctgaagcc
    13201 atgcatatcg ccaatacgcg aaccaatcag gttaccgaag ataataaagt aaagggtcat
    13261 ggtgatgact ggcggcacca gcgtctgcac ccagatacgc ataaagcgat ggatctcttt
    13321 cgcccagatg ctttttagcg ccacccagta aagatgcatc atgcgcgatc tccttgtttt
    13381 tcattaacca gtgaaacaaa cagctcttcc agacggttag ctttgttacg catacttaat
    13441 acctgaatgc cctgctcact taactgcgta aatacgctgt tgatcccctg ctcacgcagc
    13501 acttcaactt ccagcgtcgc ggtatcgacc agtcgatact gatagccatc gagcttcggt
    13561 aacggacttt tcggtgcgag atcgagaata aaggtttccg atttcagctt cgccagcagc
    13621 gccttcatcg aggtattttc caccagctca ccgtgttgaa taatgccgat attgcggcac
    13681 agcatttctg cttcttccag gtagtgtgtg gtgagaatga tggtggtgcc tttgtcgttt
    13741 aaatccttca aaaagcccca cattgagcgg cgaagttcaa tatccacgcc tgcggtcggt
    13801 tcgtcgagaa tcagtagttt aggttcatgc attaacgcac gggcaatcat taaacggcgc
    13861 ttcatcccgc cagataacat acgcgcacgt tcgttgcgtt ttccccatag atcgagttgt
    13921 ttaagatact tttcgctgcg gatgtacgct tctttgcgct ccacgccata gtaccctgcc
    13981 tgattcacca caatttgctg cacggtttca aacgggttga agttaaattc ctgcggcacc
    14041 agtcccaact gacgtttagc gttcacgaca tccttctcga gatcgtaacc aaatacgctg
    14101 acccgcccgg aggttttatt taccagagag ctgataatac cgatagtggt cgatttcccg
    14161 gccccgttcg gcccgagaag cgcataaaaa tcacccgctt cgacctgcaa atctatccca
    14221 cgaagcgcct gaacgccgcc tggataggtt tttttaagct gttgaagttc cagtgcaatg
    14281 gtcataaatt tttacttacc ttacgttctt acactttatc tgtggtttaa atcgtcccgg
    14341 agttgcccta tattagccaa acgtaattat ttggttacag gtcgttaacc tccatgaaag
    14401 acatagatac actcatcagc aacaatgcac tatggtcaaa aatgctggtg gaagaggatc
    14461 ccgggttttt tgagaaactg gcacaagcgc aaaaaccgcg ctttctatgg attggatgtt
    14521 ccgacagtcg cgttcctgca gaacgtttaa ccggtcttga gccgggcgaa ctctttgttc
    14581 accgtaatgt tgctaacctg gtcattcaca ctgacctgaa ctgcctttcc gtggttcagt
    14641 atgcagtgga tgtactcgaa gttgaacaca ttattatctg tggccactac ggttgcggcg
    14701 gcgtacaagc cgcagttgaa aacccggaac tggggcttat caacaactgg ctgctgcata
    14761 tccgcgatat ctggttcaaa catagctcat tgctcggcga aatgccgcaa gagcgccgtc
    14821 tggatacctt gtgtgaactg aacgtcatgg aacaggtgta taacctgggc cactccacca
    14881 ttatgcaatc agcgtggaaa cgcgggcaga aagttaccat tcacggctgg gcctacggca
    14941 ttcacgacgg cttgctgcgt gatctggatg tcacagcgac caaccgcgaa acccttgagc
    15001 aacgttaccg tcacgggatt tccaacctca agctgaaaca cgccaaccac aaataaaaat
    15061 gccatgccgg atgcaacaca tccggcaact tcacacttac tcgtccagca gaatcacttt
    15121 gccgatatac ggcagatgac ggtaacgctg tgcgtaatca atgccgtaac ccaccacaaa
    15181 ctcatccggg atcgagaaac cgataaattc taccgggacg ttcacttcac gacgggacgg
    15241 tttatccagc agcgtacaaa tcgccagcga cttcggttcg cgcaggctta agatctcacg
    15301 cactttcgac agtgtattcc ccgagtcgat gatatcttca acaatcagca cgtccttgcc
    15361 acggatatct tcatccagat ctttgaggat tttcacatca cgggtggtgg acatgccgct
    15421 accgtagctg gaggcggtca taaagtcgac ttcatgagat acctgaactt cacggcacag
    15481 gtccgccata aacataaatg agccacgcag cagaccaacc agcaccatat cgctgccgct
    15541 gtctttgtaa cgctcagtaa tctgacgacc cagttcggcg atacgcgctt taatctccgc
    15601 ttcggggatc attacttcta cagtatgttt catatctcta accatatgat ttaaaaacaa
    15661 atcacttcgc acgggcaggt tttggcaccg caacaaagcg caagacacgc agtataccag
    15721 taaaactatt cattcgcgga atctgttaat aaagctcgaa ttgtgatgac gatcacacat
    15781 gttaaaacct ataattaatt gctactaaaa tattaatgaa ttgaaatggt gtctctttat
    15841 ggcaattaac aatacaggct cgcgacgatt actcgtcacg ctaacagccc tttttgcagc
    15901 gctttgcggg ctgtatctac tcattggcgg aggctggctg gtcgcgattg gcggctcctg
    15961 gtactaccct atcgctggtc ttgtgatgct cggcgtcgcc tggatgctgt ggcgcagtaa
    16021 acgtgccgcg ctttggctgt acgcagccct gctgctcggc accatgattt ggggcgtctg
    16081 ggaagttggt ttcgacttct gggcgctgac tccgcgcagc gacattctgg tcttcttcgg
    16141 catctggctg atcctgccgt ttgtctggcg tcgcctggtc attcctgcca gcggcgcagt
    16201 tgccgcactg gtggtggcac tgctgattag cggtggtatc ctgacctggg ccggatttaa
    16261 cgatccgcag gaaatcaacg gcaccttaag cgccaatgcc acacctgcgg aagctatctc
    16321 acccgttgcc gatcaggact ggcctgccta tggtcgcaat caggaaggtc aacgcttttc
    16381 acctctgaaa caaattaacg ccgataacgt ccataatctg aaagaagcct gggtgttccg
    16441 tactggcgat gtgaagcagc cgaacgatcc gggcgaaatc accaatgaag tgacgccgat
    16501 taaagtgggc gacacccttt acctgtgtac cgctcaccag cgcctgtttg cgctcgatgc
    16561 cgccagcggc aaagagaaat ggcattacga tcctgagctg aaaactaacg agtctttcca
    16621 gcacgtaacc tgccgtggcg tctcttatca tgaagccaaa gcagaaacgg cttcgccgga
    16681 agtgatggcg gattgcccgc gtcgtatcat tcttccggtc aatgatggtc gactgattgc
    16741 gattaacgct gaaaacggca aactgtgcga aaccttcgcc aataaaggcg tgctcaatct
    16801 gcaaagcaat atgccagaca ccaaaccggg tctgtatgaa ccgacttcgc caccgattat
    16861 caccgataaa accatcgtga tggccggttc agttaccgat aacttctcaa cccgcgaaac
    16921 gtctggcgtg atccgtggtt ttgatgtcaa caccggggag ctgctgtggg cttttgatcc
    16981 cggcgcgaaa gatccgaacg caatcccgtc tgacgaacac acctttacct ttaactcgcc
    17041 aaactcctgg gcaccagcgg cctatgacgc gaagctggat ctggtctatc tgccgatggg
    17101 cgtgaccacg ccggatatct ggggcggtaa ccgcacaccg gaacaggaac gttatgccag
    17161 ctcgattctg gcgctgaatg ccactaccgg gaaactggcg tggagctacc agaccgttca
    17221 ccacgacctg tgggacatgg atcttccggc acagccgacg ctggcggaca tcaccgttaa
    17281 tggtcagaaa gtgccagtta tttacgctcc ggcgaaaacc ggcaacattt ttgtgctcga
    17341 tcgtcgcaat ggcgaactgg tggttccggc cccggaaaaa ccggtgccgc aaggtgctgc
    17401 gaaaggcgat tacgttactc cgacccagcc gttctctgaa ctgagcttcc gtccgaagaa
    17461 agatttgagc ggtgcggata tgtggggagc caccatgttt gaccaactgg tgtgccgcgt
    17521 gatgttccac cagttgcgct atgaaggcat tttcacgccg ccatctgaac agggcacgct
    17581 ggtcttcccg ggtaacctgg gaatgtttga atggggcggg atttccgttg atccaaatcg
    17641 tgaagtggca attgccaacc caatggcact gccgtttgtt tcgaaactga tcccacgcgg
    17701 tccgggtaac ccgatggagc agccgaaaga tgccaaaggc acgggtacgg aatccggcat
    17761 tcagccacag tacggtgtac cgtatggtgt cacgctcaac ccgttcctct caccgtttgg
    17821 tctgccatgt aaacagccag catggggtta tatctcggcg ctggatctga aaaccaatga
    17881 agtggtgtgg aagaaacgta ttggtacgcc gcaggacagt atgccgttcc cgatgcctgt
    17941 accggtgccg ttcaatatgg gtatgccgat gctgggcggg ccaatctcca cggcgggtaa
    18001 cgtgctgttt atcgccgcta cggcagataa ctacctgcgc gcttacaaca tgagcaacgg
    18061 tgaaaaactg tggcagggtc gtttaccagc gggtggtcag gctacgccaa tgacctatga
    18121 agtgaatggt aagcagtatg tggtgatctc cgcaggcggt cacggttcat ttggtacgaa
    18181 gatgggcgac tatattgtgg cttatgcgct gccggatgat gtgaagtaag acttgctcag
    18241 attgctgaca acgtgcgcgt tgttcatgcc ggatgcggcg tgaacgcctt atccagccta
    18301 caaaattgtg caaaatcaat ggattgcaca gct
//
LOCUS       DAPGUL010000086        18098 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.087, whole genome shotgun sequence.
ACCESSION   DAPGUL010000086 DAPGUL010000000
VERSION     DAPGUL010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18098)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18098)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18098
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.087"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..802
                     /locus_tag="RHX21_003225"
     CDS             <1..802
                     /locus_tag="RHX21_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000944320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="conjugal transfer protein TraH"
                     /protein_id="HDV1988377.1"
                     /translation="GCTVGGKSDSVRDKASDKDKERVTKNINIMWNALSKNRMFDGNK
                     ELKEFVMTLTGSLVFGPNGEITPLSARTTDRSIIRAMMEGGTAKIYHCNDSDKCLKVV
                     ADTPVTISRDNALKSQITKLLASIQNKAVSDTPLDDKEKGFISSTTIPVFKYLVDPQM
                     LGVSNSMIYQLTDYIGYDILLQYIQELIQQARAMVATGNYDEAVIGHINDNMNDATRQ
                     IAAFQSQVQVQQDALLVVDRQMSYMRQQLSARMLSRYQNNYHFGGSTR"
     gene            799..3621
                     /gene="traG"
                     /locus_tag="RHX21_003226"
     CDS             799..3621
                     /gene="traG"
                     /locus_tag="RHX21_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer mating pair stabilization
                     protein TraG"
                     /protein_id="HDV1988378.1"
                     /translation="MNEVYVIAGGEWLRNNLNAIAAFMGTRTWDSIEKIALTLSVLAV
                     AVMWVQRHNVMDLLGWVAVFVLISLLVNVRTSVQIIDNSDLVKVHRVDNVPVGLAMPL
                     SLTTRIGHAMVASYEMIFTQPDSVTYSKTGMLFGAELVSKSTDFLSRNPEIANLFQDY
                     VQNCVMGDIYLNHKYTLEELMASADPYTLIFSRPSPLRGVYDSNNNFVTCKDASVSLK
                     DKLNLDTQSGGKTWHYYAQQLFGGRPDPNLLFSTLIGDSYSYFYGSSKSASQIIRQNV
                     TINALKEGITSYAARNGDSASLVNLATTSSMEKQRLAHVSIGHVAMRTLPMTQTILTG
                     IAIGIFPLLVLAAVFNKLTLSVLKGYVFALMWLQSWPLLYAILNSAMTFYAKQNGAPV
                     LLSEISQIQLKYSDLASTAGYLSMMIPPLSWMMVRGLGAGFSSVYSHFASSAISPTAS
                     AAGSVVDGNYSYGNMQTENVNGFSWSTNSTTSFGQMMYQTGSGATATQTRDGNMVMDA
                     SGAMSRLPVGINATRQIAAAQQEMAREASNRAESALHGFSSSIASAWNTLSQFGSNRG
                     SSDSVTSGADSTMSAQDSMMASRMRSAVESYAKAHNISNEQATQELASRSTRASAGMY
                     GDAHAEWGVKPKILGVGGGLGVRGGGRAGIDWSDDDAHQASSGSRASYDARHDIDAKA
                     SKDFKEASDYFTSRKVSESGSHTDNNADSRVDQLSAALNSAKQSYDQYTTNMTRSHEY
                     AEMASRTESMSGQMSEDLSQQFAQYVMKHAPQDAEAILTNTSSPEIAERRRAMAWSFV
                     QEQIQPGVDNAWRESRGDIGKGMESVPSGGGSQDIIADHQGHQAIIEQRTQDSNIRND
                     VKHQVDNMVTEYKGNIGDTQNSIRGEENIVRGQYSELQNHHKTESLSQNNKYNEEKSA
                     QERMPGADSPQELMKRAKEYQDKYKQ"
     gene            3637..4134
                     /locus_tag="RHX21_003227"
     CDS             3637..4134
                     /locus_tag="RHX21_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="entry exclusion protein"
                     /protein_id="HDV1988379.1"
                     /translation="MIMRCLAHIALVTVIQFIACYLADWGNAETVFMLFFIVLWQGLF
                     IWLFSQIRKKRDVSDEFKFSKGVWYITMPVSSLLSPLLSLMVFIIGTLYELRRVSGCI
                     SIKKWGQNQLKDQYDGSEKLDFGGIEQTPTIYYNPSTGYPMHGGFDSAGNTFGTRWQD
                     YYDRQ"
     gene            4166..4897
                     /locus_tag="RHX21_003228"
     CDS             4166..4897
                     /locus_tag="RHX21_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="complement resistance protein TraT"
                     /protein_id="HDV1988380.1"
                     /translation="MKTKKLMMVTLVSSTLALSGCGAMSTAIKKRNLEVKTQMSETIW
                     LEPASERTVFLQIKNTSDKDMSGLQGKIADAVKAKGYQVVTSPDKAYYWIQANVLKAD
                     KMDLRESQGWLNRGYEGAAVGAALGAGITGYNSNSAGATLGVGLAAGLVGMAADAMVE
                     DVNYTMITDVQIAERTKATVTTDNVAALRQGTSGAKIQTSTETGNQHKYQTRVVSNAN
                     KVNLKFEEAKPVLEDQLAKSIANIL"
     gene            5150..7303
                     /gene="traD"
                     /locus_tag="RHX21_003229"
     CDS             5150..7303
                     /gene="traD"
                     /locus_tag="RHX21_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001593043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system coupling
                     protein TraD"
                     /protein_id="HDV1988381.1"
                     /translation="MSFNAKDMTQGGQIASMRIRMFSQIANIILYCLFIFFWILVGLV
                     LWVKISWQTFVNGCIYWWCTTLEGMRDLIRSQPVYEIQYYGKTFRMNAAQVLHDKYMI
                     WCGEQLWSAFVLASVVALVICLITFFVVSWILGRQGKQQSENEITGGRQLTDNPKEVA
                     RMLKKDGKDSDIRIGDLPIIRDSEIQNFCLHGTVGAGKSEVIRRLANYARQRGDMVVI
                     YDRSGEFVKSYYDPSIDKILNPLDARCAAWDLWKECLTQPDFDNTANTLIPMGTKEDP
                     FWQGSGRTIFAEAAYLMRNDPNRSYSKLVDTLLSIKIEKLRTFLRNSPAANLVEEKIE
                     KTAISIRAVLTNYVKAIRYLQGIEHNGEPFTIRDWMRGVREDQKNGWLFISSNADTHA
                     SLKPVISMWLSIAIRGLLAMGENRNRRVWFFCDELPTLHKLPDLVEILPEARKFGGCY
                     VFGIQSYAQLEDIYGEKAAATLFDVMNTRAFFRSPSHKIAEFAAGEIGEKEHLKASEQ
                     YSYGADPVRDGVSTGKDMERQTLVSYSDIQSLPDLTCYVTLPGPYPAVKLSLKYQTRP
                     KVAPEFIPRDINPEMENRLSAVLAAREAEGRQMASLFEPDVPEVVSGEDVTQAEQPQQ
                     PVSPAINDKKSDAGVNVPAGGIEQELKMKPEEEMEQQLPPGISESGEVVDMAVYEAWQ
                     REQNPDIQQKMQRREEVNINVHRERGEDVEPGDDF"
     gene            complement(7312..7710)
                     /gene="vapC"
                     /locus_tag="RHX21_003230"
     CDS             complement(7312..7710)
                     /gene="vapC"
                     /locus_tag="RHX21_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(fMet)-specific endonuclease VapC"
                     /protein_id="HDV1988382.1"
                     /translation="MLKFMLDTNICIFTIKNKPASVRERFNLNQGRMCISSVTLMELI
                     YGAEKSQMPERNLAVIEGFVSRIDVLDYDAAAATHSGQIRAELARQGRPVGPFDQMIA
                     GHARSRGLIIVTNNTREFERVDGLRIEDWS"
     gene            complement(7710..7937)
                     /gene="vapB"
                     /locus_tag="RHX21_003231"
     CDS             complement(7710..7937)
                     /gene="vapB"
                     /locus_tag="RHX21_003231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin system antitoxin VapB"
                     /protein_id="HDV1988383.1"
                     /translation="METTVFFSNRSQAVRLPKAVALPENVKRVEVIAVGRTRIITPAG
                     ETWDEWFDGHNVSADFMDNREQPGMQERESF"
     gene            8019..13289
                     /gene="traI"
                     /locus_tag="RHX21_003232"
     CDS             8019..13289
                     /gene="traI"
                     /locus_tag="RHX21_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001463032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugative transfer relaxase/helicase TraI"
                     /protein_id="HDV1988384.1"
                     /translation="MMSIAQVRSAGSAGNYYTDKDNYYVLGSMGERWAGRGAEQLGLQ
                     GSVDKDVFTRLLEGKLPDGADLSRMQDGSNKHRPGYDLTFSAPKSVSVMAMLGGDKRL
                     IDAHNQAVDFAVRQVEALASTRVMTDGQSETVLTGNLVMALFNHDTSRDQEPQLHTHA
                     VVANVTQHNGEWKTLSSDKVGKTGFIENVYANQIAFGRLYREKLKEQVEALGYETEVV
                     GKHGMWEMPGVPVEAFSGRSQAIREAVGEDASLKSRDVAALDTRKSKQHVDPEVRMAE
                     WMQTLKETGFDIRAYRDAADQRAETRTQTPGPASQDGPDVQQAVTQAIAGLSERKVQF
                     TYTDVLARTVGILPPENGVIERARAGIDEAISREQLIPLDREKGLFTSGIHVLDELSV
                     RALSRDIMKQNRVTVHPEKSVPRTAGYSDAVSVLAQDRPSLAIVSGQGGAAGQRERVA
                     ELVMMAREQGREVQIIAADRRSQMNLKQDERLSGELITGRRQLQEGMAFTPGNTVIVD
                     QGEKLSLKETLTLLDGAARHNVQVLITDSGQRTGTGSALMAMKDAGVNTYRWQGGEQR
                     PATIISEPDRNVRYARLAGDFAASVKAGEESVAQVSGVREQAILTQAIRSELKTQGVL
                     GRPEVTMTALSPVWLDSRSRYLRDMYRPGMVMEQWNPETRSHDRYVIDRVTAQSNSLT
                     LRDAQGETQVVRISSLDSSWSLFRPEKMPVADGERLRVTGKIPGLRVSGGDRLQVASV
                     SEDAMTVVVPGRAEPATLPVSDSPFMALKLENGWVETPGHSVSDSAKVFASVTQMAMD
                     NATLNGLARSGRDVRLYSSLDETRTAEKLARHPSFTVVSEQIKARAGETLLETAISLQ
                     KTGLHTPAQQAIHLALPVVESKNLAFSMVDLLTEAKSFAAEGTSFTELGGEINAQIKR
                     GDLLYVDVAKGYGTGLLVSRASYEAEKSILRHILEGKEAVTPLMERVPGELMEKLTSG
                     QRAATRMILETSDRFTVVQGYAGVGKTTQFRAVMSAVNMLPESERPRVVGLGPTHRAV
                     GEMRSAGVDAQTLASFLHDTQLLQRSGETPNFSNTLFLLDESSMVGNTDMARAYALIA
                     AGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAADVAIMKEIVRQTPELREAVYSLINR
                     DVERALSGLESVKPSQVPRQEGAWVPEHSVTEFSHSQEAKLAEAQQKAMLKGEAFPDI
                     PMTLYEAIVRDYTGRTPEAREQTLIVTHLNEDRRVLNSMIHDAREKAGELGKEQVMAP
                     VLNTANIRDGELRRLSTWETHRDALALVDNVYHRIAGISKDDGLITLQDAEGNTRLIS
                     PREAVAEGVTLYTPDTIRVGTGDRMRFTKSDRERGYVANSVWTVTAVSGDSVTLSDGQ
                     QTRVIRPGQERAEQHIDLAYAITAHGAQGASETFAIALEGTEGNRKQMAGFESAYVAL
                     SRMKQHVQVYTDNRQGWTDAINNAVQKGTAHDVLEPKSDREVMNAERLFSTARELRDV
                     VAGRAVLRQAGLAGGDSPARFIAPGRKYPQPYVALPAFDRNGKSAGIWLNPLTTDDGN
                     GLRGFSGEGRVKGSGDAQFVALQGSRNGESLLADNMQDGVQIARDNPDSGVVVRIAGE
                     GRPWNPGTITGGRVWGDIPDNSVQPGAGNGEPVTAEVLAQRQAEEAIRRETERRADEI
                     VRKMAENKPDLPDGKTEQAVRDIAGLERDRSAISEREAALPESVLREPQRVREAVREV
                     ARENLLQERLQQMERDMVRDLQKEKTLGGD"
     gene            13309..14055
                     /gene="traX"
                     /locus_tag="RHX21_003233"
     CDS             13309..14055
                     /gene="traX"
                     /locus_tag="RHX21_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer pilus acetylase TraX"
                     /protein_id="HDV1988385.1"
                     /translation="MTTDNTNTTRNDSLAARTDTWLQSLLVWSPGQRDIIKTVALVLM
                     VLDHANRILHLDQSWMFLVGRGAFPLFALVWGLNLSRHTHIRQEAINRLWGWAVIAQF
                     AYYLAGFPWYEGNILFAFAVAAQVLTWCETRTWWRSAEAMLLLAMWLPFSGTSYGIAG
                     LLMLAVSHRLYRAEDRMERLALVACLLAVIPALNLATSDAAAVAGLVMTVLTVGLVSC
                     TGKSLPRFWYGDFFPTFYACHLTVLGVLAV"
     gene            14114..14974
                     /locus_tag="RHX21_003234"
     CDS             14114..14974
                     /locus_tag="RHX21_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDV1988386.1"
                     /translation="MKITDHKLPEGIALTFRVPEGNIKHPLILLCHGFCGIRNVLLPS
                     FANAFTEAGFATITFDYRGFGESEGERGRLVPAMQTEDIISVINWAEKQVCIDNQRIG
                     LWGTSLGGCHVFNAAAQDKRVKSIVSQLAFADGEVLVTGEMNELEKASFLSTLNKMAE
                     KKKNTGKEMFVGVTRVLSDNESKVFFEKVKGQYPEMDIKIPFLTVMETLQYKPAESAA
                     KVQCPVLVVIAGQDSVNPPEQGRALYDAVASGTKELYEEADACHYDIYEGAFFERVAA
                     VQTQWFKKHL"
     gene            15077..15634
                     /locus_tag="RHX21_003235"
     CDS             15077..15634
                     /locus_tag="RHX21_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000139380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fertility inhibition protein FinO"
                     /protein_id="HDV1988387.1"
                     /translation="MTEQKRPVLTLKRKTEGETPIRSRKTIINVTTPPKWKVKKQKLA
                     EKAAREAELAAKKAQARQALSIYLTLPSLDEAVNTLKPWWPGLFDGNTPRLLACGIRE
                     VLLDEVSQRNIPLSHKKLRRALKAITRSESYLGAMKAGACRYDTEGYVTEHITQEEEQ
                     YAQARLEKVRRQNRIKDELRAILAE"
     gene            15789..15992
                     /locus_tag="RHX21_003236"
     CDS             15789..15992
                     /locus_tag="RHX21_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988388.1"
                     /translation="MAVSSGLSEHSSIYRYQREGRHAVRQEIRGFFREAAEVWQNAAR
                     LAPCEAWRDFALKRASACRCKCR"
     gene            16735..17196
                     /locus_tag="RHX21_003237"
     CDS             16735..17196
                     /locus_tag="RHX21_003237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="HDV1988389.1"
                     /translation="MKKYIPVVLFVFSCQVFSADIHGRGVRVLDGNTIDVMLSQHPVR
                     VRLVNIDAPEKKQEYGRWSEKIMKSLVAGKTVTVTYFQRDHYGRILGQVYAPDGMNVN
                     QFMVRAGDAWVYEQYNTDPVLPVLQGEVRQQKRGLWADSAPVPPWVWRSRK"
     gene            17299..17681
                     /locus_tag="RHX21_003238"
                     /pseudo
     CDS             17299..17681
                     /locus_tag="RHX21_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109264.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            17904..>18098
                     /locus_tag="RHX21_003239"
     CDS             17904..>18098
                     /locus_tag="RHX21_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001362723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="HDV1988390.1"
                     /translation="MKYLNTTDCSLFLAERSKFMTKYALIGVLAVCATVLCFLLIFRE
                     RLCELNIHRGNTVVQVTLAYE"
BASE COUNT         4523 a         4181 c         5271 g         4123 t
ORIGIN      
        1 gggatgtacc gttggcggga aatctgacag tgtcagggat aaagccagcg acaaggataa
       61 ggagcgggtg accaaaaaca tcaacatcat gtggaatgcg ctttccaaaa acagaatgtt
      121 tgacggcaac aaagagctga aagaatttgt gatgacgctg accggctcac tggtgtttgg
      181 tcccaacggc gaaatcacac cgctgtcagc cagaaccact gaccgctcaa ttatccgggc
      241 catgatggaa ggcggcacag caaaaattta tcactgcaac gattctgata aatgcctgaa
      301 agtggtggca gacacaccgg tgactatcag ccgggataat gcactgaagt ctcagattac
      361 taaacttctg gccagcattc agaacaaggc ggtcagtgac acgcctctgg atgacaagga
      421 aaaaggcttt atttccagta ccaccatccc cgtcttcaaa tacctggttg acccgcagat
      481 gctcggagtt tccaacagca tgatttacca gctgacggac tatatcggtt acgacatcct
      541 gctgcagtac attcaggagc tgatacagca ggcccgggcg atggtggcca cgggaaatta
      601 tgacgaagcg gttatcggac atattaacga caacatgaat gatgccaccc ggcagattgc
      661 ggcgtttcag tcacaggtgc aggtacagca ggatgcgttg ctggttgtcg atcgtcagat
      721 gagctacatg cgtcagcagc tttccgcccg catgctcagt cgttaccaga acaactatca
      781 cttcggaggg agcacgcggt gaatgaagtt tatgtgattg ccggtggtga gtggttgcgg
      841 aataacctga acgccattgc cgcctttatg ggaaccagga cgtgggattc cattgaaaaa
      901 attgcgctca cattgtctgt tctcgcggtg gccgtaatgt gggtacagcg gcacaacgtg
      961 atggatttgc tgggctgggt ggccgtattt gtgcttatca gcctgctggt taatgtccgc
     1021 acatcggtgc agattattga taacagtgac ctggtcaaag ttcaccgggt ggataatgtg
     1081 ccggtcggac tggcgatgcc actttcactg acgacccgta tcgggcatgc aatggtggcc
     1141 agttacgaga tgatcttcac gcaaccggac agtgtcacct acagcaaaac ggggatgctg
     1201 tttggcgcag aactggtatc aaaaagcacc gactttttgt cccgcaatcc ggaaatcgcc
     1261 aatcttttcc aggattatgt gcagaactgt gtgatggggg atatttacct gaaccacaaa
     1321 tacacgctgg aggagctgat ggcctccgct gatccctaca cgctgatttt ttcccgcccc
     1381 agcccgctgc ggggcgttta tgacagcaat aataatttcg taacctgtaa ggacgcgtcg
     1441 gtttcgctga aagacaagct gaatctggac acacagagtg gcggaaaaac ctggcattat
     1501 tatgcccagc agctatttgg tggacgccct gatcctaacc tgctgttcag tacgctgatt
     1561 ggcgacagtt acagttactt ctatggctca agtaaatcag ccagccagat catccgccag
     1621 aatgtcacca tcaatgcgct gaaggagggg atcaccagtt atgccgcacg taatggtgat
     1681 tcggccagcc tggtgaatct ggccaccacg tcatcgatgg agaaacaacg tctggcacat
     1741 gtctccatcg gtcatgtggc gatgcggaca ctgcccatga cgcagaccat cctgacgggg
     1801 atcgccatcg gtattttccc gctcctggta ctggcggctg tattcaacaa actgacgctg
     1861 tctgtcctga aaggttatgt gtttgccctg atgtggctgc agtcatggcc actcttgtac
     1921 gccattctga acagtgccat gacattttat gcgaaacaga atggtgcgcc ggtgttgctc
     1981 tctgaaattt cacagataca actgaaatac tccgatctgg cttccactgc cgggtatctt
     2041 tccatgatga tcccgccatt atcctggatg atggtcaggg ggcttggggc cggattttcc
     2101 agtgtgtaca gccatttcgc ttcctctgct atcagcccga ctgccagtgc ggcaggtagt
     2161 gtggttgacg gtaattactc ctacggtaac atgcagacgg aaaacgtgaa cggcttcagc
     2221 tggagcacca acagcaccac gtcgtttggt cagatgatgt accagaccgg cagtggcgca
     2281 accgccacac agacccgtga cggtaatatg gtgatggatg caagcggagc gatgtcccgt
     2341 ttaccggtcg gtatcaatgc aacgcgtcag attgcagcgg cacaacagga aatggcccgg
     2401 gaggcgtcga acagagcaga aagtgccctg catggtttca gcagcagtat tgccagtgcc
     2461 tggaacacgc tcagtcagtt tggttctaac cgggggagca gtgactctgt caccagtggt
     2521 gctgacagta cgatgagtgc acaggactcc atgatggcca gccgtatgcg cagtgcagtg
     2581 gaaagctatg cgaaggcgca taatatcagt aatgagcagg cgactcagga actggcatcc
     2641 agaagtacga gagcttctgc cgggatgtat ggagatgctc atgctgaatg gggggttaaa
     2701 cctaaaattc ttggtgttgg tggaggatta ggcgttagag gtggtggtcg ggctggcatt
     2761 gactggagtg atgatgatgc gcatcaggcc agcagtggtt cacgggccag ctatgatgct
     2821 cgtcatgata ttgacgctaa agccagtaag gactttaaag aggccagcga ttactttacc
     2881 agtcgcaaag tcagtgaatc cggcagccat actgacaata atgctgattc ccgggtggat
     2941 caactgtctg cagccctgaa ttcagcgaaa cagagttacg accagtacac gacgaatatg
     3001 acccgcagcc atgaatatgc tgaaatggca tcccgtactg aaagcatgag tgggcagatg
     3061 agcgaagatt tgtcgcaaca gtttgcacag tatgtgatga aacacgcacc gcaggatgcc
     3121 gaagctattc tgacaaatac cagttcgccg gagattgcag aacgccgtcg ggcaatggcc
     3181 tggtcttttg tgcaggaaca gatacagcct ggtgttgata atgcctggcg ggaatcccgt
     3241 ggcgatattg gtaaaggaat ggagagcgta ccttcgggtg gaggcagtca ggatattatt
     3301 gctgaccatc agggacatca ggccattatt gagcaaagaa cgcaggacag taatatccgt
     3361 aatgatgtaa aacatcaggt tgataatatg gtcacagaat ataaagggaa tataggtgat
     3421 actcagaaca gcatacgtgg cgaggaaaat attgtaagag gacagtattc tgaactgcag
     3481 aatcaccata aaacagagtc attatctcag aataataaat ataatgaaga aaagtcggct
     3541 caggaaagaa tgcccggagc tgacagtcca caggaactga tgaaaagggc aaaggagtat
     3601 caggataagt ataagcaata atactgtgtt tgggagatga taatgagatg tttagcccat
     3661 attgctctgg taacagtgat acagtttatc gcctgttatc tggctgattg ggggaatgcc
     3721 gaaacagttt ttatgctgtt cttcatagtg ctatggcagg gactgtttat ctggttgttc
     3781 tctcaaatac gaaaaaaacg ggatgtgtcg gatgagttta agtttagtaa aggcgtttgg
     3841 tatataacga tgccagtatc ttccttactc tctccgttat taagcctgat ggtttttatc
     3901 attggtacac tatacgaatt aaggcgagtt agtggttgca taagcataaa aaaatggggg
     3961 caaaatcaac tcaaagacca atatgatggg agtgaaaagt tagacttcgg gggcattgaa
     4021 cagaccccaa cgatctacta taacccttca accggatatc ctatgcatgg aggctttgat
     4081 tcagcgggaa atacttttgg gactcgttgg caggactatt atgacaggca ataagaaaac
     4141 tgtagtttgt aaaaaaggta atttgatgaa aacaaaaaaa ttgatgatgg ttacactggt
     4201 cagttccact ctggcccttt cagggtgtgg tgcgatgagc acagcaatca agaagcgtaa
     4261 ccttgaggtg aagactcaga tgagtgagac catctggctt gaacccgcca gcgaacgcac
     4321 ggtatttctg cagatcaaaa acacgtctga taaagacatg agtgggctgc agggcaaaat
     4381 tgctgatgct gtgaaagcaa aagggtatca ggtggtgact tctccggata aagcctacta
     4441 ctggattcag gcgaatgtgc tgaaggccga taagatggat ctgcgggagt ctcagggatg
     4501 gctgaaccgt ggttatgaag gcgcagcagt tggtgcagcg ttaggtgccg gtatcaccgg
     4561 atataattcc aattctgccg gtgccacact cggtgtgggc cttgctgccg gtctggtggg
     4621 tatggctgca gatgcgatgg tggaagatgt gaactatacc atgatcacgg atgtgcagat
     4681 tgcagagcgt actaaggcaa cggtgacaac ggataatgtt gccgccctgc gtcagggcac
     4741 atcaggtgcg aaaattcaga ccagtactga aacaggtaac cagcataaat accagacccg
     4801 tgtggtctca aatgcgaaca aggttaacct gaaatttgaa gaggcgaagc ctgttctcga
     4861 agaccagctg gccaaatcaa tcgcaaatat tctctgatta tcttccggag gctggtctga
     4921 ccggcctcct gactgacgcc tcgctttgct cgttgtccaa ccccggggag aaataaaata
     4981 aattttattt ctccccggcg tttccgaaat aaatatgaaa acactgagcg gttgtgcaaa
     5041 ttctttgtgc gaccgtgaag tgttgccggc gaagccggaa tttaacggtt attaatcttt
     5101 tcatcattaa taatcagtcc gactgacttt ctttcttcag aatatcatca tgagttttaa
     5161 cgcaaaggat atgacccagg gcggtcagat tgcgtccatg cgtatccgca tgttcagtca
     5221 gatcgccaat atcatacttt actgcctgtt tatttttttc tggatcctag ttggtctggt
     5281 tttatgggta aaaataagct ggcagacgtt tgtgaatggc tgcatttact ggtggtgcac
     5341 cacgctggaa ggcatgcggg atttaatcag gtcccagccg gtctatgaga tccagtatta
     5401 cggcaaaacc ttccggatga acgcggctca ggtactgcat gataaatata tgatctggtg
     5461 cggtgagcag ttatggtcgg cattcgttct ggcgtctgtc gtggccctgg ttatctgcct
     5521 gatcaccttc tttgttgtct cctggattct ggggcgtcag ggtaaacaac agagcgaaaa
     5581 tgaaatcaca ggtggtcgtc agctgactga caatccgaaa gaggtggcca ggatgctgaa
     5641 aaaagatggc aaggattccg atatccggat tggcgatctg ccgattatcc gggattctga
     5701 aatccagaac ttctgtctgc acggcactgt cggggccggt aagtcggagg ttatccgtcg
     5761 tctggccaac tacgcccgtc agcgtggtga tatggtggtg atttatgacc gttcggggga
     5821 atttgttaaa agttactatg atccctccat cgataaaatc ctgaatccgc tggatgcacg
     5881 ctgtgctgcc tgggatttgt ggaaggagtg cctgacacag ccagattttg ataataccgc
     5941 aaatactctg atcccgatgg ggacaaaaga ggacccgttc tggcagggtt caggacgtac
     6001 catttttgcg gaagcggcat acctgatgcg taatgacccc aaccgcagct acagcaaact
     6061 ggtggacaca ctgctttcca tcaaaattga aaagctgcgt accttcctgc gtaattcacc
     6121 ggcggccaac ctggtggaag agaaaatcga gaaaacggcc atatccatcc gtgctgtgct
     6181 gaccaactac gtgaaagcca tccgttacct gcaggggatt gagcataacg gtgagccctt
     6241 caccatccgt gactggatgc gtggtgtccg ggaagatcag aaaaacggct ggctgtttat
     6301 ttcgtcgaac gccgacaccc atgcctccct gaagccggtg atctccatgt ggctgtccat
     6361 tgctattcgt ggtctgctgg caatgggaga aaaccgtaac cgtcgtgtgt ggtttttctg
     6421 tgacgagtta cccacgttac acaaactgcc ggacctggtg gagatcctgc cggaagcccg
     6481 taagttcggt ggctgttatg tgtttggtat ccagtcctat gcccagctgg aagatatcta
     6541 cggtgagaaa gcggctgcca cgctgtttga cgtcatgaac acccgtgcct ttttccgttc
     6601 tcccagccat aagattgcag agttcgctgc cggtgaaatt ggtgagaaag agcacctgaa
     6661 agccagcgag cagtattcct acggtgctga tccggtacgt gacggggtat cgaccggtaa
     6721 ggatatggag cgtcagacgc tggtcagtta ttccgacatt cagtctctgc cggatctgac
     6781 ctgttatgtc accctgcccg gaccgtatcc ggcagtaaaa ctctccctga aatatcagac
     6841 acgaccgaag gtcgctccgg agtttattcc gcgtgacatc aacccggaaa tggagaaccg
     6901 tctgagtgcc gtacttgccg caagggaagc agaaggtcgt cagatggcca gcctcttcga
     6961 accggatgtc ccggaggttg tttccggaga agacgtgact caggctgaac agccgcaaca
     7021 gccggtgtct cctgccatca acgataagaa gtcagatgca ggtgtgaatg ttccggcagg
     7081 ggggatcgag caggagctga aaatgaaacc ggaagaagag atggaacagc aactgccacc
     7141 cgggatcagt gaatccggtg aagtggtgga tatggccgtt tatgaggcat ggcaacggga
     7201 gcagaatccg gatatccagc agaagatgca gcgtcgtgaa gaggtgaaca tcaatgtgca
     7261 ccgggagcgc ggggaggatg ttgagccggg agatgatttc tgatgaacag gtcagctcca
     7321 gtcttcaatt ctcagaccgt ccacacgttc aaattcccgg gtgttattag tcacaataat
     7381 cagtccccga ctgcgggcat gacctgcgat catttgatca aatggcccga cagggcgtcc
     7441 ctgacgggca agttctgctc ttatctggcc gctgtgtgtg gctgcggcag cgtcgtaatc
     7501 cagaacatca atgcgggaaa caaatccctc gatcacagcg agattacgtt caggcatctg
     7561 gcttttttct gcaccatata tcagctccat cagggtgacc gaactgatac acattctccc
     7621 ctggttcagg ttaaaacgct ccctgacgct ggcgggtttg ttctttatcg tgaaaatgca
     7681 gatgttggta tcgagcataa acttcagcat cagaatgact ccctttcctg catgccgggc
     7741 tgttccctgt tatccataaa atcggcgctg acgttgtgtc cgtcgaacca ttcgtcccat
     7801 gtctctccgg ctggcgtaat gattctggtt cgtccgacag caatcacttc aacgcgtttt
     7861 acgttttccg gcaatgcaac cgcttttggc agtctgaccg cctggctgcg gttgctgaaa
     7921 aatacggtgg tttccattat ttgcctcctt atgtggatat gtcttgtgta tatccattgt
     7981 gggattgata ccgggatatg tcaaagggat atacgtttat gatgagtatc gcgcaggtca
     8041 gatcggccgg aagtgccggt aactattata ccgacaagga taattactat gtgctgggca
     8101 gcatgggaga acgctgggcc ggcagggggg ctgaacagct ggggctgcag ggcagcgtcg
     8161 ataaggatgt ttttacccgt cttctggagg ggaagctgcc ggacggagcg gatttaagcc
     8221 gcatgcagga tggcagtaat aagcatcgtc ccggctacga cctgaccttc tccgccccca
     8281 aaagtgtctc cgtgatggcc atgttaggcg gtgataaacg tcttattgat gcacataacc
     8341 aggccgtgga ttttgctgtc cgtcaggtgg aggcgctggc ttccacacgg gttatgacgg
     8401 acggacagtc agaaacggtg ctgaccggta atctggtgat ggcactgttt aaccacgaca
     8461 ccagtcgcga tcaggaacca cagttacaca cacatgcggt agtggccaat gtcacgcagc
     8521 ataacggcga gtggaagaca ctgagcagtg acaaagtggg gaaaacgggg ttcattgaga
     8581 atgtgtacgc taatcagatt gccttcggca ggctctaccg ggaaaaactg aaagagcagg
     8641 ttgaggcgct gggctatgaa acggaagtgg ttggtaagca cggtatgtgg gagatgccgg
     8701 gcgtaccggt ggaggccttc tccggacgct cacaggctat ccgggaggcc gtcggggaag
     8761 acgcctcgct gaaatcccgg gatgtggcgg cactggatac gcgaaaatcc aaacagcacg
     8821 tcgatcctga agtcagaatg gctgaatgga tgcagacgct gaaggaaacc gggttcgaca
     8881 tccgggcgta tcgtgacgcg gcggaccaac gggcggagac ccgcacgcag acgcccggac
     8941 ccgcttcaca ggacgggccg gatgtgcagc aggcggtgac acaggccatt gccggattaa
     9001 gtgaacgcaa agtgcagttt acgtacactg acgtgctggc cagaacggtc ggcatactgc
     9061 cgccggaaaa tggtgtgatt gaacgggcac gcgccggtat cgatgaggcc atcagccgtg
     9121 agcagcttat ccccctcgat cgtgagaagg ggctgttcac gtccgggatt catgtgctcg
     9181 atgagctgtc agtccgggca ctcagtcgtg acatcatgaa acagaaccgg gtgaccgtac
     9241 atccggagaa aagtgtcccc cggacggccg gttacagcga tgcggtcagt gttctggcac
     9301 aggatcgccc gtcgctggct attgtgtccg ggcagggcgg tgcagccggg cagcgtgagc
     9361 gggtggcgga gctggtcatg atggcccggg agcaggggcg ggaggtgcag attatcgccg
     9421 ctgaccgtcg ctcgcagatg aacctgaagc aggatgaacg gctgtccggt gagctgataa
     9481 ccggacgtcg tcagctgcag gagggcatgg ccttcacgcc gggcaatact gttatcgttg
     9541 accagggcga aaaactctcc ctgaaagaga cgttaaccct gctggacggt gccgcacgtc
     9601 ataacgtaca ggtcctgata accgacagcg ggcagcgaac cggtacaggc agtgcactga
     9661 tggccatgaa agatgccggg gtgaacacat atcgctggca ggggggagaa cagcggccgg
     9721 ccaccatcat cagtgaaccg gaccgtaatg tccgctatgc ccggctggca ggagattttg
     9781 ctgccagcgt gaaagccgga gaagagagcg tggcacaggt cagcggggta cgggaacagg
     9841 ccatactgac acaggccatt cgcagtgagc tgaaaacaca gggcgtgctc ggacgcccgg
     9901 aggtaaccat gaccgccctg tcgccggtct ggctggacag ccggagccgt tatctgcggg
     9961 atatgtaccg tccggggatg gtgatggagc agtggaaccc ggagacacgc agtcatgacc
    10021 gctatgttat cgaccgggtg acggcgcaga gtaacagcct gaccctgcgg gatgcgcagg
    10081 gtgaaacgca ggtggtgcgt atttcctccc tggacagcag ctggtcgctg ttccggccgg
    10141 aaaaaatgcc agtggcagac ggcgagcgac tgagggtgac agggaaaatt cccggactcc
    10201 gcgtctccgg cggtgaccgc ctgcaggtgg catccgtcag tgaagatgcg atgacggttg
    10261 ttgtgccggg gcgggctgaa ccggccaccc tgcctgtgag cgattcacca ttcatggcac
    10321 tgaagctgga gaacggctgg gtggaaacgc ctgggcattc cgtcagcgac agtgcgaagg
    10381 tttttgcctc cgtcacacag atggcaatgg acaacgccac cctgaacggt ctggcccgca
    10441 gcggtcgtga tgtccggctg tattcctcac tggatgaaac ccgtactgcg gaaaaacttg
    10501 cccgccatcc ctcctttacg gtggtttctg agcagataaa ggcgcgtgcc ggtgagacat
    10561 tgctggaaac cgctatcagt ctgcagaaaa ccgggcttca cacgccggca cagcaggcta
    10621 ttcatctggc gcttcctgtg gtggaaagta aaaacctggc cttcagcatg gtggacctgc
    10681 tgacagaggc gaagtcgttt gctgcagaag gaaccagttt tactgaactg ggaggggaaa
    10741 tcaatgcgca gataaaacgc ggtgatttac tgtatgtgga tgtggcaaaa ggctatggca
    10801 caggcctgct ggtttcccgt gcgtcgtatg aggcagaaaa gagcattctt cgccatattc
    10861 tcgaaggtaa ggaggcggtc acgccactga tggagagagt acctggcgaa ctcatggaga
    10921 aactgacatc aggacagcgt gccgctaccc gcatgatact ggaaacgtcc gaccgtttca
    10981 cggtggtgca gggctatgcc ggtgtgggta agaccacaca gttccgggcg gtgatgtcag
    11041 ccgtgaacat gctgccggag agtgaacgtc cccgtgtcgt ggggctgggg cccacgcacc
    11101 gtgcggtcgg tgagatgcgc agcgccggcg tggatgcaca gacgctggcg tcctttctgc
    11161 atgacacgca gctgctgcag cgcagcggag aaacgccgaa tttcagcaac acgctgttcc
    11221 tgctcgatga gagctctatg gtgggcaata ccgacatggc acgggcatac gccctgattg
    11281 cggccggtgg cggtcgtgcc gtggccagtg gtgacacgga ccagttgcag gccatcgcgc
    11341 ccggtcagcc tttccgtctc cagcagacgc gcagtgctgc cgatgtggcc atcatgaagg
    11401 agattgtgcg ccagacgccg gagctgcggg aggcggtata cagcctgatt aaccgggatg
    11461 tggaaagggc actgtccggg cttgagagtg tgaaaccgtc tcaggtgcca cgtcaggagg
    11521 gcgcatgggt accggagcac tccgtgacgg agttcagtca cagccaggaa gcgaaactgg
    11581 cagaagcgca gcagaaggcg atgctgaaag gtgaggcttt tccggatatt cccatgacac
    11641 tgtatgaagc cattgtccgc gattataccg gcaggacgcc ggaagcacgg gagcagacgc
    11701 tgattgtcac gcatctgaat gaggaccggc gcgtactgaa cagcatgatt catgatgcac
    11761 gggaaaaggc cggtgagctg ggaaaagagc aggtcatggc gcctgtcctg aacacagcga
    11821 atatacgcga cggggagttg cgtcgtctct ccacctggga gacacatcgg gacgcacttg
    11881 ccctggtgga taatgtgtat caccggattg ccggtatcag caaggatgac gggctgataa
    11941 ccttgcagga tgcggaaggt aacacgcggc tgatttcgcc ccgggaggcg gtggctgaag
    12001 gcgtcacact gtacactccg gacaccatcc gggtgggaac cggtgaccgg atgcgcttca
    12061 cgaagagtga ccgggagcgc ggttatgtgg ccaacagcgt ctggacggtg acagcggttt
    12121 ccggtgacag tgtcacgctg tcggacggac agcagacccg ggtgattcgc cccggtcagg
    12181 agcgggcaga gcaacatatt gacctggcct atgccatcac cgcccacggt gcgcaggggg
    12241 caagtgaaac ctttgccatt gcgcttgaag gcacggaagg taaccggaaa cagatggccg
    12301 gttttgagtc agcctacgtg gccctgtcgc gtatgaagca gcatgtgcag gtgtataccg
    12361 ataaccgtca gggctggacg gatgccatta acaatgccgt acagaaagga actgcccacg
    12421 atgtgctaga gccgaaatcg gaccgggagg tcatgaatgc agagcggctg ttcagtacgg
    12481 cgcgggagct gcgggacgtg gtggccggcc gtgccgttct ccgtcaggca gggctggccg
    12541 ggggagacag tcctgcacgg tttattgcac ccgggcgcaa atatccgcag ccgtatgtgg
    12601 cactgccggc ttttgaccgt aacggcaagt cagctggtat ctggctgaac ccgctgacca
    12661 cggatgacgg aaacgggctg cggggcttca gtggtgaagg ccgggtgaaa ggcagcgggg
    12721 atgcgcagtt cgtggccctg cagggcagcc gtaacggaga gagcctgctg gctgataata
    12781 tgcaggatgg tgtccagatt gcccgtgata atcctgacag cggtgtggtg gtaagaatcg
    12841 ccggtgaagg tcgtccgtgg aatcccggta ccatcaccgg tggtcgcgtg tggggggata
    12901 tcccggacaa cagcgttcag ccgggagccg gaaatggcga accggtcacg gcagaggtac
    12961 tggcacagcg gcaggctgaa gaggccatcc gccgtgaaac ggaacgccgt gcggatgaaa
    13021 ttgtccgtaa aatggcagag aacaaacctg acctgccgga cggcaaaaca gagcaggctg
    13081 tcagggatat tgccgggctg gagcgtgaca ggtctgccat atctgaacgg gaagctgcgc
    13141 tgccggagag tgtactgcgt gaaccacaac gggtgcggga agcggtccgg gaggttgccc
    13201 gggaaaatct gctgcaggag cgactgcagc agatggagcg ggatatggtt cgtgacctgc
    13261 agaaagagaa aaccctgggc ggagactgac acaggaagat aaacgctgat gacaacggat
    13321 aacacgaaca caacacgtaa tgattcactg gctgcccgga ccgatacctg gttgcagtcg
    13381 ttgctggtct ggtcacccgg acagcgggat atcatcaaaa cggtggcact ggtgctgatg
    13441 gttctggacc atgcaaaccg cattctgcat ctggaccagt cgtggatgtt tctggtcggg
    13501 cgtggggcct ttccgctgtt tgccctggtg tgggggctga atctgtcccg tcatacgcat
    13561 atccggcagg aggccattaa ccggctgtgg ggatgggcgg tgattgccca gttcgcatat
    13621 tatctggccg gctttccctg gtatgagggg aatatcctgt ttgcctttgc agttgcggca
    13681 caggtgctga catggtgtga aacgcgcacc tggtggcgtt ccgcagaggc catgttgctt
    13741 ctggcaatgt ggttgccttt ctccggcacc agttacggca ttgccgggct gctgatgctg
    13801 gcagtcagcc acaggctgta ccgggcggaa gacagaatgg aacgtctggc gctggtcgcc
    13861 tgcctgctgg ctgttattcc ggcgcttaac cttgccacca gtgatgcagc ggcggtggcc
    13921 ggccttgtga tgacggtgct gactgttggt ctggtgtcct gtacagggaa atcactaccc
    13981 cgtttctggt acggggattt tttcccgacg ttctatgcct gtcatcttac tgtgctgggc
    14041 gttctggctg tgtgactggt atgatgctgg cgctgattct gcttattaat aaacaacata
    14101 acacaggata tttatgaaaa ttacggatca caaactccct gaaggtattg ccctgacatt
    14161 tcgtgtcccg gaaggaaata taaaacatcc tttgattctc ttatgccatg gattttgcgg
    14221 tatccggaat gttctgctgc cttcctttgc gaatgcgttt acagaagccg ggtttgcaac
    14281 gattactttt gattatcgtg gattcggtga gagtgaaggg gaacgaggtc gtctggttcc
    14341 ggcaatgcag accgaagata ttatttcagt tatcaactgg gcagaaaagc aggtatgtat
    14401 tgataatcaa cgtataggat tatggggaac atcgctgggt gggtgtcatg tattcaatgc
    14461 agctgcgcag gataaaagag tgaaaagtat tgtcagccag ctggcttttg ctgacggtga
    14521 ggttctggtt accggagaaa tgaatgaact ggagaaagct tcttttctgt ccacgctgaa
    14581 taaaatggca gaaaagaaga aaaataccgg gaaagagatg tttgtggggg ttacccgggt
    14641 actgagtgat aatgaatcaa aggtattctt cgagaaggta aaaggtcagt atcctgaaat
    14701 ggatataaaa atacctttcc ttacggttat ggagacgttg caatataaac cggcagagag
    14761 cgcagccaaa gtacagtgcc cagttttggt tgttattgcc ggccaggata gtgttaatcc
    14821 accagaacag ggaagagcct tatatgatgc tgttgcttct ggtactaagg aattatacga
    14881 ggaagctgac gcatgccatt atgatattta tgaaggcgcg ttttttgaac gtgtggcggc
    14941 agtacagacg caatggttta aaaaacatct ttaattgtcg gtattaatat gtcagaggtc
    15001 gttgaggtca gcttaatatc atagtgagta gtttcaacga cctggaggac atattttcac
    15061 aaaggtcagg gcaatcatga cagagcagaa acgaccggta ctgacactga aacggaaaac
    15121 ggaaggggaa acaccgatcc ggagccggaa aaccatcatc aatgtcacca cgccaccaaa
    15181 atggaaggtg aaaaagcaga aactggcgga gaaggctgcc cgggaagcag agctggcggc
    15241 gaagaaagca caggccagac aggcgctgtc catttatctg acgctgccct cgctggatga
    15301 ggcggtgaac actctgaaac cctggtggcc gggattgttt gacggtaaca cgccccggct
    15361 tcttgcctgt ggtatccggg aagttttact ggatgaggtg tctcagcgga atatcccgct
    15421 ctctcataaa aaactgcgca gggcactgaa ggccatcacc cgttcagaaa gctatcttgg
    15481 cgccatgaaa gccggtgcct gccgctatga tacagaaggc tatgtgacag aacatatcac
    15541 acaggaagaa gaacagtatg cgcaggcgcg cctggaaaag gtgcgcagac agaaccggat
    15601 caaggatgag ctgcgggcga tcctggcaga ataataaaag cgccctctgt atgacagagg
    15661 gcaacagcga aaaaaatcgg gaaaacagac atccagagtt ttgatggaga aaaacatcca
    15721 accgttcagg gatgtttcat aatgtttctg acataatccg ggtgtcgggt caagaggagg
    15781 gataaaaaat ggctgtatcc agtggattat ctgaacacag cagtatttat cgctatcagc
    15841 gcgaggggcg tcatgccgtc cgtcaggaga ttcgtggctt tttcagggaa gcggcagagg
    15901 tctggcagaa tgcggcccgg ctggcaccct gtgaagcatg gcgggatttt gctctgaaga
    15961 gggcatctgc atgtcggtgt aagtgccgat aaaaataacc cccgtcgcgg agctccgggg
    16021 gatcagactt atatggcaga tcgttattat tattatagtg gtgtaagaag gagttgccct
    16081 gtctttcaaa cggacatcac agaattaaca tatttcacat cccgggtaag ccagcaggga
    16141 taaaaaatgt gatgaatttc aagaagcagg aggtgacagt ggcatgcata acagtagggt
    16201 tatccggtga atctgacaga cagccgggct gtattcgcgg caggataaag aaaaaccggg
    16261 agatgactct cccggtccgt cttatcgcta atcccctgag cagggcatgt atgacttatc
    16321 tatgaccgtt atattcagcg ccacatccgg tagcctgcga tataacacag ttatcctgtc
    16381 agcaagagca ggtatgatga atacacggag attaaaaata taatctccgt cacatgttac
    16441 ccacggaaac cggtaacgcc ttcacgggaa atatgtgaca gaaaaagcag cctccgttac
    16501 tccaggtatc aggaggctga ataatgcatg agacgttgtt tcttatgtgt ctggtcaggc
    16561 tggctgacca gcgtttttag taacacatag ccatatgtgt attaagtcac ctcatcttat
    16621 tttgttgaat tgatcacaac tcaacggttt attttttgcg tgatacgtga gccattattc
    16681 atcccggcat ggaattcatg caatcacgaa aagtaatcag tgacggagag taaaatgaag
    16741 aaatatatac cagtggtatt atttgttttt tcatgtcagg tattttctgc tgatattcat
    16801 ggacggggcg tgcgtgttct ggatggcaat accattgacg tcatgttatc tcagcatccg
    16861 gtgcgtgtcc gtcttgttaa tattgatgca cctgaaaaga aacaggaata tggacggtgg
    16921 tctgaaaaaa taatgaaatc tctggttgcg ggaaaaacgg ttactgtcac atattttcag
    16981 cgagatcatt atggtcgtat tctcgggcag gtttatgcac cagacggaat gaatgttaat
    17041 cagtttatgg tccgtgcagg cgatgcatgg gtttatgagc agtacaacac cgatcctgtt
    17101 cttcctgtcc tgcagggaga agtacgacag cagaaacgtg gtctgtgggc agacagcgct
    17161 cctgttccgc cctgggtatg gcgctcacgg aaataatgat atttctgtgg ctattgagtt
    17221 ctcattgaaa tgcgatattt aaaagcatga agcatattac attattaact tatttctctg
    17281 ttaatgaaag gtgaacaaat gaactatcag gcagtatcag aattaatcac atcgtctaat
    17341 cataatgttc ttatagtggg ggaatcagct tcgaagttga tagcttttta aataaactga
    17401 atatcactga ttataagtat tatgatttca gccagattta cagttgttct gacagaacat
    17461 taaatgatta tgctgttatt tttatcagga atgcgctgaa cgccagtgag catattatta
    17521 tttttaattg tacaggatgg tctgatttga ataatgaatc tgccgtcatg cagtttgcca
    17581 gagtggcacg aaaatcagga aaacaactga tagtcgcagt aagagaacag gatatgaaaa
    17641 aaatggaagc agagtttgga aggatcataa aaatccactg acgccttcgc gttgctcagt
    17701 tgtccaaccc cggggacggg aaaaagcaag ttttccccgc ccctggcgtt tctgtagtga
    17761 aaagcgggaa atggagggaa tggtcagtaa cagggaatgt ggtattatcg cggcgggtgt
    17821 ctgagccttt ctggttcagg caagacgcag gtaccagaaa tgcgaagacc ccacttgtta
    17881 atccattaac tcgtgaggcc tgcatgaagt accttaacac tactgattgt agcctcttcc
    17941 ttgcagagag gtcaaagttt atgacgaaat atgcccttat cggggtgctc gccgtgtgcg
    18001 ccacggtgtt gtgtttttta ctgatattca gggaacggtt atgtgagctg aatattcaca
    18061 ggggaaatac agtggtgcag gtaactctgg cctacgaa
//
LOCUS       DAPGUL010000087        18042 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.088, whole genome shotgun sequence.
ACCESSION   DAPGUL010000087 DAPGUL010000000
VERSION     DAPGUL010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18042
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.088"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            297..1196
                     /gene="yegS"
                     /locus_tag="RHX21_003240"
     CDS             297..1196
                     /gene="yegS"
                     /locus_tag="RHX21_003240"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid kinase YegS"
                     /protein_id="HDV1988391.1"
                     /translation="MAEFPASLLILNGKSTDNLPLREAIMLLREEGMTIHVRVTWEKG
                     DAARYVEEARKLGVATVIAGGGDGTINEVSTALIQCEGDDIPALGILPLGTANDFATS
                     VGIPEALDKALKLAIAGNAIAIDMAQVNKQTCFINMATGGFGTRITTETPEKLKAALG
                     GVSYIIHGLMRMDTLQPDRCEIRGENFHWQGDALVIGIGNGRQAGGGQQLCPNALIND
                     GLLQLRIFTGDEILPALVSTLKSDEDNPNIIEGASSWFDIQAPHEITFNLDGEPLSGQ
                     NFHIEILPAALRCRLPPDCPLLR"
     gene            complement(1278..2051)
                     /locus_tag="RHX21_003241"
     CDS             complement(1278..2051)
                     /locus_tag="RHX21_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDV1988392.1"
                     /translation="MNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLE
                     QKGVVTRFHGGAAKIMSGNSETETQEVGFKERFQLASAPKNRIAQAAVKMIHEGMTVI
                     LDSGSTTMLIAEGLMTAKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMHGS
                     IAERSLQDINADLMFVGADGIDAVNGITTFNEGYSISGAMVTAANKVIAVLDSSKFNR
                     RGFNQVLPIEKIDIIITDDAVSEVDKLALQKTRVKLITV"
     gene            complement(2157..3197)
                     /gene="gatD"
                     /locus_tag="RHX21_003242"
     CDS             complement(2157..3197)
                     /gene="gatD"
                     /locus_tag="RHX21_003242"
                     /EC_number="1.1.1.251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDV1988393.1"
                     /translation="MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPR
                     IFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQ
                     CAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAKGCE
                     NKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAP
                     QMQSVLRELRFNQLILETAGVPQTVELAVEIAGPHAQLALVGTLHQDLHLTSATFGKI
                     LRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFTQAVRDIA
                     RNAMPGKVLLIP"
     gene            complement(3245..4600)
                     /locus_tag="RHX21_003243"
     CDS             complement(3245..4600)
                     /locus_tag="RHX21_003243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol permease IIC component"
                     /protein_id="HDV1988394.1"
                     /translation="MFSEVMRYILDLGPTVMLPIVIIIFSKILGMKAGDCFKAGLHIG
                     IGFVGIGLVIGLMLDSIGPAAKAMAENFDLNLHVVDVGWPGSSPMTWASQIALVAIPI
                     AILVNVAMLLTRMTRVVNVDIWNIWHMTFTGALLHLATGSWMIGMAGVVIHAAFVYKL
                     GDWFARDTRNFFELEGIAIPHGTSAYMGPIAVLVDAIIEKIPGVNRIKFSADDIQRKF
                     GPFGEPVTVGFVMGLIIGILAGYDVKGVLQLAVKTAAVMLLMPRVIKPIMDGLTPIAK
                     QARSRLQAKFGGQEFLIGLDPALLLGHTAVVSASLIFIPLTILIAVCVPGNQVLPFGD
                     LATIGFFVAMAVAVHRGNLFRTLISGVIIMSITLWIATQTIGLHTQLAANAGALKAGG
                     MVASMDQGGSPITWLLIQVFSPQNIPGFIIIGAIYLTGIFMTWRRARGFIKQEKVVLA
                     E"
     gene            complement(4604..4888)
                     /gene="gatB"
                     /locus_tag="RHX21_003244"
     CDS             complement(4604..4888)
                     /gene="gatB"
                     /locus_tag="RHX21_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIB"
                     /protein_id="HDV1988395.1"
                     /translation="MKRKIIVACGGAVATSTMAAEEIKELCQNHNIPVELIQCRVNEI
                     ETYMDGVHLICTTAKVDRSFGDIPLVHGMPFISGVGIEALQNKILTILQG"
     gene            complement(4919..5371)
                     /gene="gatA"
                     /locus_tag="RHX21_003245"
     CDS             complement(4919..5371)
                     /gene="gatA"
                     /locus_tag="RHX21_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIA"
                     /protein_id="HDV1988396.1"
                     /translation="MTNLFVRSGISFVDRSEVLTHIGNEMLAKGVVYDTWPQALIARE
                     AEFPTGIMLEQHAIAIPHCEAIHAKSSAIYLLRPTNKVHFQQADDDNDVEVSLVIALI
                     VENPQQQLKLLRCLFGKLQQPDIVETLITLPETQLKEYFTKYVLDSDE"
     gene            complement(5381..6643)
                     /gene="gatZ"
                     /locus_tag="RHX21_003246"
     CDS             complement(5381..6643)
                     /gene="gatZ"
                     /locus_tag="RHX21_003246"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatZ"
                     /protein_id="HDV1988397.1"
                     /translation="MKTLIARHKAGEHIGICSVCSAHPLVIEAALAFDRNSTRKVLIE
                     ATSNQVNQFGGYTGMTPADFREFVFTIADKVGFARERIILGGDHLGPNCWQQENADAA
                     MEKSVELVKEYVRAGFSKIHLDASMSCAGDPIPLAPETVAERAAVLCFAAESVATDCQ
                     REQLSYVIGTEVPVPGGEASAIQSVHITHVEDAANTLRTHQKAFIARGLTEALTRVIA
                     IVVQPGVEFDHSNIIHYQPQEAQPLAQWIESTRMVYEAHSTDYQTRTAYWELVRDHFA
                     ILKVGPALTFALREAIFALAQIEQELIAPENRSGCLAVIEEVMLDEPQYWKKYYRTGF
                     NDSLLDIRYSLSDRIRYYWPHSRIKNSVETMMVNLEGVDIPLGMISQYLPKQFERIQS
                     GELSAIPHQLIMDKIYDVLRAYRYGCAE"
     gene            complement(6672..7526)
                     /gene="gatY"
                     /locus_tag="RHX21_003247"
     CDS             complement(6672..7526)
                     /gene="gatY"
                     /locus_tag="RHX21_003247"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416599.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HDV1988398.1"
                     /translation="MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAANLHAP
                     VIIAGTPGTFTHAGTENLLALVSAMAKQYHHPLAIHLDHHTKFDDIAQKVRSGVRSVM
                     IDASHLPFAQNISRVKEVVDFCHRFDVSVEAELGQLGGQEDDVQVNEADAFYTNPAQA
                     REFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDI
                     QQTIKLGICKINVATELKNAFSQALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIA
                     DCGCEGRA"
     gene            complement(7836..8888)
                     /gene="fbaB"
                     /locus_tag="RHX21_003248"
     CDS             complement(7836..8888)
                     /gene="fbaB"
                     /locus_tag="RHX21_003248"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006820796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fructose-bisphosphate aldolase"
                     /protein_id="HDV1988399.1"
                     /translation="MTDIAQLLGKDADNLLQHRCMTIPSDQLYLPGHDYVDRVMIDNN
                     RPPAVLRNMQTLYNTGRLAGTGYLSILPVDQGVEHSAGASFAANPLYFDPKNIVELAI
                     EAGCNCVASTYGVLASVSRRYAHRIPFLVKLNHNETLSYPNTYDQTLYASVEQAFNMG
                     AVAVGATIYFGSEESRRQIEEISAAFERAHELGMVTVLWAYLRNSAFKKDGVDYHVSA
                     DLTGQANHLAATIGADIVKQKMAENNGGYKAINYGYTDDRVYSKLTSENPIDLVRYQL
                     ANCYMGRAGLINSGGAAGGETDLSDAVRTAVINKRAGGMGLILGRKAFKKSMADGVKL
                     INAVQDVYLDSKITIA"
     gene            9145..10422
                     /locus_tag="RHX21_003249"
     CDS             9145..10422
                     /locus_tag="RHX21_003249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1988400.1"
                     /translation="MKTTAKLSFMMFVEWFIWGAWFVPLWLWLSKSGFSAGEIGWSYA
                     CTAIAAILSPILVGSITDRFFSAQKVLAVLMFAGALLMYFAAQQTTFAGFFPLLLAYS
                     LTYMPTIALTNSIAFANVPDVERDFPRIRVMGTIGWIASGLACGFLPQMLGYADISPT
                     NIPLLITAGSSALLGVFAFFLPDTPPKSTGKMDIKVMLGLDALILLRDKNFLVFFFCS
                     FLFAMPLAFYYIFANGYLTEVGMKNATGWMTLGQFSEIFFMLALPFFTKRFGIKKVLL
                     LGLVTAAIRYGFFIYGSADEYFTYALLFLGILLHGVSYDFYYVTAYIYVDKKAPVHMR
                     TAAQGLITLCCQGFGSLLGYRLGGVMMEKMFAYPEPVNGLTFNWSGMWTFGAVMIAII
                     AVLFMIFFRESDNEITAIKADDRDIALTQGEVK"
     gene            10419..11423
                     /locus_tag="RHX21_003250"
     CDS             10419..11423
                     /locus_tag="RHX21_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HDV1988401.1"
                     /translation="MKTERILGALYGQALGDAMGMPSELWPRSRVKAHFGWIDRFLPG
                     PKENNAACYFNRAEFTDDTSMALCLADALLEREGKIDPDLIGRNILDWALRFDAFNKN
                     VLGPTSKIALNAIRDGKPVAELENNGVTNGAAMRVSPLGCLLPARDVDSFIDDVALAS
                     SPTHKSDLAVAGAVVIAWAISRAIDGESWSAIVDSLPSIARHAQQKRITTFSASLAAR
                     LEIALKIVRNADGTESASEQLYQVVGAGTSTIESVPCAIALVELAQTDPNRCAVLCAN
                     LGGDTDTIGAMATAICGALHGVNAIDPALKAELDAVNQLDFNRYATALAKYRQQREAV
                     "
     gene            11420..12385
                     /locus_tag="RHX21_003251"
     CDS             11420..12385
                     /locus_tag="RHX21_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDV1988402.1"
                     /translation="MSGARLHTLLPELTSRQPVMVVGAAVIDVIADAYALPWRGCDIE
                     LKQQSVNVGGCALNIAVALKRLGIEAGNALPLGQGVWAEIIRNRMAKEGLISLIDNAE
                     GDNGWCLALVEPDGERTFMSFSGVENQWNRQWLARLTVAPGSLLYFSGYQLASPCGEL
                     LVEWLEKLQDVTPFIDFGPRIGDIPDALLARIMACRPLVSLNRQEAEIAAERFALSAE
                     ITTLGKQWQEKFAAPLIVRLDKEGAWYFSNDASGCIPAFPTQVVDTIGAGDSHAGGVL
                     AGLASGLPLADAVLLGNAVASWVVGHRGGDCAPTREELLLAHKNV"
     gene            complement(12359..13105)
                     /locus_tag="RHX21_003252"
     CDS             complement(12359..13105)
                     /locus_tag="RHX21_003252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDV1988403.1"
                     /translation="MEQAHTQLIAQLNERILAADNTPLYIKFAETVKNAVRSGVLEHG
                     NILPGERDLSQLTGVSRITVRKAMQALEEEGVVTRSRGYGTQINNIFEYSLKEARGFS
                     QQVVLRGKKPDTLWVNKRVVKCPEEVAQQLAVEAGSDVFLLKRIRYVDEEAVSIEESW
                     VPAHLIHDVDAIGISLYDYFRSQHIYPQRTRSRVSARMPDAEFQSHIQLDSKIPVLVI
                     KQVALDQQQRPIEYSISHCRSDLYVFVCEE"
     gene            complement(13157..13979)
                     /locus_tag="RHX21_003253"
                     /pseudo
     CDS             complement(13157..13979)
                     /locus_tag="RHX21_003253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416605.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
     gene            complement(14044..14844)
                     /gene="thiD"
                     /locus_tag="RHX21_003254"
     CDS             complement(14044..14844)
                     /gene="thiD"
                     /locus_tag="RHX21_003254"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HDV1988404.1"
                     /translation="MKRINALTIAGTDPSGGAGIQADLKTFSALGAYGCSVITALVAQ
                     NTRGVQSVYRIEPDFVAAQLDSVFSDVRIDTTKIGMLAETDIVEAVAERLQRYQIQNV
                     VLDTVMLAKSGDPLLSPSAVATLRSRLLPQVSLITPNLPEAAALLDAPHARTEQEMLE
                     QGRSLLAMGCGAVLMKGGHLDDEQSPDWLFTREGEQRFTAPRIMTKNTHGTGCTLSAA
                     LAALRPRHTNWADTVQEAKSWLSSALAQADTLEVGHGIGPVHHFHAWW"
     gene            complement(14841..15629)
                     /gene="thiM"
                     /locus_tag="RHX21_003255"
     CDS             complement(14841..15629)
                     /gene="thiM"
                     /locus_tag="RHX21_003255"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HDV1988405.1"
                     /translation="MQVDLLSSAQSAHALHLFHQHSPLVHCMTNDVVQTFTANTLLAL
                     GASPAMVIETEEASQFAAIASALLINVGTLTQPRAQAMRAAVEQAKSSQTPWTLDPVA
                     VGALDYRRHFCHELLSFKPAAIRGNASEIMALAGIANGGRGVDTTDAAANAIPAAQTL
                     ARETGAIVVVTGEVDYVTDGHRAVGIHGGDPLMTKVVGTGCALSAVVAACCALPGDTL
                     ENVASACHWMKQAGERAVARSEGPGSFVPHFLDALWQLTQEVQA"
     regulatory      complement(15664..15760)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(15852..16124)
                     /gene="rcnR"
                     /locus_tag="RHX21_003256"
     CDS             complement(15852..16124)
                     /gene="rcnR"
                     /locus_tag="RHX21_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni(II)/Co(II)-binding transcriptional repressor
                     RcnR"
                     /protein_id="HDV1988406.1"
                     /translation="MSHTIRDKQKLKARASKIQGQVVALKKMLDEPHECAAVLQQIAA
                     IRGAVNGLMREVIKGHLTEHIVHQGDELKREEDLDVVLKVLDSYIK"
     gene            16245..17069
                     /gene="rcnA"
                     /locus_tag="RHX21_003257"
     CDS             16245..17069
                     /gene="rcnA"
                     /locus_tag="RHX21_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel/cobalt efflux protein RcnA"
                     /protein_id="HDV1988407.1"
                     /translation="MTEFTTLLQQGNAWFFIPSAILLGALHGLEPGHSKTMMAAFIIA
                     IKGTIKQAVMLGLAATISHTAVVWLIAFGGMVISKRFTAQSAEPWLQLISAVIIIGTA
                     FWMFWRTWRGERNWLENMHEYDHEHHHHDHEDHHDHGHHHHHEHGEYQDAHARAHAND
                     IKRRFDGREVTNWQILLFGLTGGLIPCPAAITVLLICIQLKALTLGATLVVSFSIGLA
                     LTLVTVGVGAAISVQQVAKRWSGFNTLAKRAPYFSSLLIGLVGVYMGVHGFMGIMR"
     gene            17288..17626
                     /gene="rcnB"
                     /locus_tag="RHX21_003258"
     CDS             17288..17626
                     /gene="rcnB"
                     /locus_tag="RHX21_003258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni(II)/Co(II) efflux transporter accessory
                     subunit RcnB"
                     /protein_id="HDV1988408.1"
                     /translation="MTIKNKMLLGVLLLVTSAAWAAPATAGSTNTSGISKYELSSFIA
                     DFKHFKPGDTVPEMYRTDEYNIKQWQLRNLPAPDAGTHWTYMGGAYVLISDTDGKIIK
                     AYDGEIFYHR"
     gene            complement(17708..>18042)
                     /locus_tag="RHX21_003259"
     CDS             complement(17708..>18042)
                     /locus_tag="RHX21_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV1988409.1"
                     /translation="NLLGQQNQTSRKMQVYLSSSDLLTNSNTILKGAEDNGVGFILES
                     NGSPVTLLNITNSSKGYTNLKEIAAKSKLTDTTVSIPITASYYVYDTNKIKSGALEAT
                     ALINVKYD"
BASE COUNT         4438 a         4628 c         4359 g         4617 t
ORIGIN      
        1 ctacataagt aggaattacg gacattgagg cccttcaggg taactccatg ggggctttaa
       61 tatattatat tgaagatgcc actgtttagt tgaatattag gtatatgctc ttttttgaaa
      121 tttatcggtg gcagccgtta gtattcgctg tccccattgc aagctcctgg tggtaaccac
      181 tgaatcctcc atacttgaac tgacttttta tcctccgact ttcatcctgt tctgactcca
      241 ccttttgttt tctgctctac actatctaca gaccaatcat aaaggcacat acgatcatgg
      301 cagaatttcc cgccagctta ctgattctta atggcaaaag tactgacaat ctacccttgc
      361 gcgaagcaat tatgctgttg cgtgaggaag gaatgacgat ccatgtgcgg gtcacctggg
      421 agaaaggcga tgccgcacga tatgtagagg aggcccggaa gttgggcgtc gcaacggtga
      481 ttgccggtgg tggcgatggc accattaatg aagtttctac ggcgttgatt cagtgtgagg
      541 gggatgacat acccgcgctg ggaattttgc cattaggaac cgccaatgat tttgccacca
      601 gtgtagggat tcctgaggca ctggataagg cgctgaaact ggcaattgcc ggtaacgcca
      661 ttgcgataga tatggcgcag gtcaacaaac aaacctgttt tattaatatg gcgacaggcg
      721 gatttgggac gcgtattacc acagaaacgc cggaaaaatt aaaagccgcg ctgggtggcg
      781 tctcttacat cattcatggc ttaatgcgca tggatactct gcaaccggac cgttgtgaaa
      841 tccgcggtga aaactttcac tggcaaggtg acgccctggt cattggtatt ggtaacgggc
      901 gtcaggccgg tggcggtcag caattgtgtc cgaacgcgtt aattaacgat ggcttgctgc
      961 aactgcgcat ttttaccggc gatgaaattc ttccggctct cgtatcaacc ttaaaatctg
     1021 acgaagataa cccgaatatt atcgaaggcg cttcgtcgtg gtttgatata caagccccac
     1081 acgaaatcac ttttaatctt gatggcgaac cgttgagcgg acaaaacttt catattgaaa
     1141 tacttccggc ggcgttgcgt tgtcgattac caccagattg tccattattg cgttaatcaa
     1201 actattctct cttgaaccag ggagaatccg aaatgccgga tgcggtgtaa ataccttatc
     1261 cggcatacag aacaatacta caccgtaatt aattttaccc gtgtcttctg caatgccagt
     1321 ttatccacct ctgatacagc atcatcggta ataataatgt caattttttc gattggcagt
     1381 acctgattaa aaccgcgacg gttaaatttc gatgaatcga gaacggcaat cactttatta
     1441 gcggcggtga ccatcgcacc gctaatcgaa taaccttcat taaaggtcgt aataccatta
     1501 accgcatcaa taccatcagc accgacaaac attaaatcgg cattaatatc ctgcagggaa
     1561 cgttcagcaa tagatccatg catagatcgc gttttatggc ggaccgtgcc accgcagacg
     1621 accagagtaa tgtctttatt ttcggaaagg gcaaacgcag ccgggagact gttggtaatc
     1681 accgtgatat ttttagcggt cattaatcct tcggcgataa gcattgtggt acttccgctg
     1741 tcgagaataa cggtcatccc ttcatggatc attttgactg ccgcctgcgc tattctgttt
     1801 ttgggcgcgc tggcgagctg aaatcgctct ttaaacccga cttcctgggt ctcggtttca
     1861 ctattaccgg acattatttt cgccgcaccg ccatgaaagc gcgtaaccac gcctttttgt
     1921 tcgagaaagc gcaaatcggc acggattgtc gcttccgagg cagcaaatac tcccgccaga
     1981 tcctgaacaa gcacggttcc ctgttcattc actaattgga tgatcttatt ccttcgctcg
     2041 aatgaattca tcgtcattta cccatattca attgtggcta gtgtaaacga agggggacca
     2101 ttggtgaatg atctgttttg cacaataccg ggccagcatc acgctggccc gcggtttcat
     2161 ggaatgagca acactttgcc cggcatggca ttacgagcga tgtcacgcac cgcctgggtg
     2221 aagctttcaa agcttccacg gtgagcgatt aatggctcca ggcttaactt acgttctgtc
     2281 agcaaccggc tcgccgtttc ccactcctgc cccggccaag ggctggaata gttcatccaa
     2341 ctgccgataa ccgtcagctc tttacgcaat attttgccaa acgttgccga tgttaaatgc
     2401 agatcctgat gcaacgtgcc caccagcgcc agttgggcat gaggaccggc aatctctacc
     2461 gccagttcga cagtttgcgg tacgccagcc gtctcgagga taagctgatt aaaacgcagt
     2521 tcgcgtaaaa cgctctgcat ttgcggcgcg ctcatttcgc tactgttaaa tgtttgcatc
     2581 gcaccgaaag attttgccag tgccagtttt tctgagctaa tgtcgatagc cgtcacactc
     2641 tttgctccca gcgcgacagc gcactgaata gccagcaggc caatggttcc ggcaccaata
     2701 ataataacgt ttttattctc acaacctttc gctaaatgaa aagcatgcag accaacggta
     2761 atcggctcaa taaaagcccc atcctcaata ggcatatccg tgggtagagc aaagacattt
     2821 tttcgcttaa cgacaatata ttcagcaaat ccaccatcac gccgcgagcc aataaaatca
     2881 tattttgcgc actgggaata aaaccctttc agacactctg gacaagtaaa acagggtaat
     2941 aacggcacac aggcaaccgc atcgccaggg tgtaaatcat caacaccgga tcccaccgca
     3001 tcaatatagc cgctaaattc atggcctaac gttattggat aataatgtgc accattttta
     3061 aatatcctgg gtaaatcgga accacataag cccgagctgg caatttttac ccgcacctca
     3121 tcctgatgtt taatttcagg aatgacgctt tctgcaacgc gcacgatacc atcagtatca
     3181 ttcaccactg atttcataaa aactcctgat tgttaagggg gataacctcc ccctcaggta
     3241 aaaattattc tgcgagaacg actttctctt gtttaataaa gccacgcgct ctacgccagg
     3301 tcatgaaaat accggtcaga taaattgcac cgataataat gaaaccggga atattttgcg
     3361 gggagaaaac ctgaatcagt aaccaggtaa tgggagaacc gccctgatcc attgaagcca
     3421 ccataccccc ggcttttaac gccccagcat tagccgccag ttgggtgtgc aaaccaatag
     3481 tttgcgtcgc gatccacaga gtgatgctca tgatgatgac acccgagatt aaggtgcgga
     3541 acagatttcc acgatgcacg gcgaccgcca tcgccacgaa gaagccgatg gtggcaagat
     3601 cgccaaacgg cagcacctga ttacccggca cacaaacagc aattaaaatg gtgagtggga
     3661 taaaaatcag gcttgccgat accaccgccg tatgtcccag cagcaacgcc ggatcaaggc
     3721 caatcaggaa ctcctgaccg ccgaacttcg cctgtaaacg actacgagcc tgcttagcga
     3781 tgggcgttaa accatccatg atgggtttaa tcacccgtgg cattagcagc atcactgccg
     3841 ccgtttttac cgccagctgc aatacacctt tgacatcgta acccgcgagg atgccgataa
     3901 tcagccccat cacaaaaccc acggtgacag gctcgccaaa tggaccaaat ttgcgctgaa
     3961 tatcgtcggc gctaaattta attcggttaa cgcctgggat tttctcgatg atagcatcga
     4021 ccagcaccgc aatcggcccc atatacgccg acgtaccgtg cggaatagca ataccttcca
     4081 gctcaaagaa atttcgggta tcgcgggcaa accagtcgcc gagcttataa acaaacgccg
     4141 cgtgaattac gacacctgcc atccctatca tccatgaacc ggttgccaga tgcagcaacg
     4201 cgccggtgaa ggtcatatgc cagatattcc agatatcaac atttaccacc cgcgtcatac
     4261 gggtcagtaa catcgccacg ttaaccaata tcgcaatcgg aatcgccacc agcgcaattt
     4321 gcgaagccca ggtcattggt gaagagcccg gccagccgac atcgaccaca tgcagattca
     4381 ggtcgaaatt ttccgccatc gctttcgccg ccggaccaat ggaatccagc attaagccaa
     4441 tcacaaggcc aatgccaaca aagccaatcc cgatatgcag acccgcttta aagcaatcgc
     4501 ctgccttcat gcctaatatt ttagaaaaaa taatgatgac aatcggaagc atcaccgtag
     4561 ggccgaggtc gagaatataa cgcatgactt ctgaaaacat aggtcacccc tgtaagatag
     4621 tcagaatttt attttgtaat gcttcgatac cgacaccaga aataaaaggc atgccgtgaa
     4681 ctaacggaat atcgccaaaa ctacgatcca ctttggcagt ggtgcatatc aaatgcacac
     4741 catccatata ggtttctatt tcattaaccc gacactggat taattcaaca ggaatattat
     4801 gattctgaca caactcttta atttcttccg ccgccatcgt agaggtcgca accgcgcctc
     4861 cgcaagcgac aataatcttg cgtttcataa atagtccttt ttattgttac agagggattt
     4921 attcgtctga atctaaaaca tactttgtga agtattcctt taactgagtt tcaggaagag
     4981 taattagtgt ctcgacgata tcgggctgtt gtaacttgcc aaataaacag cgtaaaagtt
     5041 tcaattgctg ctgcggattt tccacaatca acgcaataac caacgacacc tccacgtcgt
     5101 tatcatcatc cgcttgctga aaatgaactt tatttgttgg ccttaacaga taaatggctg
     5161 acgacttagc atgaatcgcc tcacaatgcg gtatagcaat ggcgtgctgc tcaagcatta
     5221 tcccggtagg gaattctgct tctctggcaa ttaatgcctg tggccaggta tcataaacca
     5281 cacctttcgc gagcatctca ttaccgatat gggttaaaac ttcgctacga tcgacaaaag
     5341 aaattccgct acgaacaaac aggttagtca tataccgtcc ttattccgca cagccgtagc
     5401 gataggcgcg caaaacatca taaattttat ccataatcag ctgatgcggt attgctgata
     5461 attccccgga ctgaatgcgt tcaaattgtt tgggaagata ctgactaatc atgcccagtg
     5521 ggatgtccac gccttcaaga ttcaccatca tcgtttcgac gctattttta atccgactat
     5581 gcggccagta ataacgaata cgatccgaca ggctgtaacg aatatccagt aatgaatcgt
     5641 taaaacccgt acgataatat tttttccagt attgcggttc gtcgagcatc acttcttcaa
     5701 ttaccgccag gcaaccgctg cgattttcag gggcgataag ttcctgctca atttgtgcca
     5761 gtgcaaatat cgcctcgcgt aaagcaaagg ttaatgcggg accgactttc aatattgcaa
     5821 agtgatcgcg gactaattcc caataagccg tccgggtctg gtaatcggta gaatgtgctt
     5881 cataaaccat tcgggtgctt tctatccatt gcgccagcgg ctgcgcttcc tgcggctgat
     5941 aatggataat attgctgtga tcaaattcca cgcccggctg caccacgatg gcaatcacgc
     6001 gtgttaacgc ctctgtcagc ccacgggcaa taaaggcctt ttgatgcgta cgtaaagtat
     6061 tggcggcatc ttcaacatgg gtgatgtgta ctgactgaat ggcgctggcc tcaccgcccg
     6121 gaaccggaac ttcggtgcca atgacatagc tcagttgctc acgctggcaa tctgtcgcca
     6181 cactttccgc agcaaagcaa agcacagcag ctcgttccgc aaccgtttct ggtgctaacg
     6241 gtatgggatc ccccgcgcag gacattgacg catcaagatg aattttactg aaaccggcac
     6301 gaacatattc ctttaccagc tcgacggatt tttccatcgc cgcatccgca ttttcttgct
     6361 gccagcagtt tggccccaga tgatcgccgc cgagaataat gcgttcgcgt gcaaacccaa
     6421 ctttatcggc aatcgtaaaa acaaattcgc gaaagtctgc cggtgtcatt ccggtataac
     6481 cgccaaattg attgacctgg tttgacgttg cttcaatcag cactttgcgc gtgctgttgc
     6541 gatcaaatgc cagcgccgct tcgataacca acggatgggc agaacagact gaacatatgc
     6601 cgatatgttc accagcttta tgccgggcaa ttaacgtttt catgtttttt ccttattaaa
     6661 tggcaggtgc gttatgccct gccctcgcag ccacaatcgg caatcacttt gctcaccaca
     6721 tcgcgcattg cggatttagc cgactgcaaa taatcccggg gatcggtcgc ttcagggtgc
     6781 tcggtcaggt aattttttaa cgcctgcgag aaggcatttt tcagctccgt tgcaacgttg
     6841 attttgcata tccccagttt gatggtttgc tgaatatcct tagtcgataa ccctgacgcg
     6901 ccatgcagca ccagcggtaa gttcacccac tggcgaatgt tctccagtcg agaaaaatca
     6961 agcgccggtg cgctggcata catcccatga gccgtgccga tggcgaccgc cagggaatca
     7021 attccggttg cctcggcaaa ttcacgcgcc tgagcggggt tggtataaaa agcatcggct
     7081 tcattgactt gcacatcatc ttcctggccg ccaagttgcc ccagctccgc ttcgacgctg
     7141 acatcaaagc gatggcaaaa atccaccacc tctttgaccc gtgaaatatt ttgcgcaaaa
     7201 ggcaaatgcg aggcgtcaat catgactgag cgcacgccag aacgaacctt ctgagcgata
     7261 tcgtcaaatt tcgtgtgatg gtcgagatga attgccagtg gatggtgata ttgcttcgcc
     7321 atcgcgctga ccagcgccaa cagattttct gtaccagcat gagtaaatgt gccaggcgtt
     7381 ccggcgatga tgaccggcgc atgcaggttg gcagcggttt ccaccaccac ttgcatcgtt
     7441 tcgagattgt gaatattgaa tgccggaacc gcataaccgc cgcgctgtgc gttgttcagc
     7501 atctgctttg tcgataccac gtacattttc atatcctgtc gtttgttttc gatttcaaaa
     7561 tataatgaaa tgatttgttt ttaaatgtcg agataacgat cacaaaaacg acaatgtgaa
     7621 aattgttcga ggagtaaaag gcaaaaaaaa acggcctccc gatagggaag ccgtagcaaa
     7681 gtgcgcgtgt ttttatgccg gatgcggtgt aaacatacgt ggcagtgcta tgtaggcatg
     7741 ataagacgct tccgcgtcgc atcaggcata ggttgccgga tgcagtgtaa acgccttatc
     7801 cgtcctacgg ggtggtgctg ttcgtatgag gcgtatcagg caatagtaat tttgctatcg
     7861 agataaacgt cctgcacggc attaatcagt ttcacgccgt cagccatcga tttcttgaac
     7921 gccttacgtc caagaatcag ccccattccg ccagcgcgtt tgttgataac cgcagtacgc
     7981 actgcatcgc tgaggtcagt ttcaccgccc gcagcaccgc cggagtttat caacccagcc
     8041 cgacccatat agcagttagc taactgataa cgcaccagat caatcgggtt ttcgctggtc
     8101 aatttgctgt aaacacgatc gtcggtgtaa ccgtaattaa ttgctttata gccgccgtta
     8161 ttttccgcca ttttttgttt gacgatatct gcaccgatgg ttgccgccag atggtttgcc
     8221 tgaccggtca ggtcggcgga aacatggtaa tcaacgccat ctttcttaaa ggcggagtta
     8281 cgcaaatagg cccacagcac tgtcaccata cccagctcgt gcgcacgttc aaaagccgca
     8341 gaaatttctt caatctggcg acgtgactct tccgagccaa aatagatagt cgcaccaacc
     8401 gcaaccgcgc ccatgttgaa cgcctgctcc acgctggcat acagcgtttg atcgtaggta
     8461 ttcgggtaac ttagcgtctc gttgtgatta agtttgacga ggaatggaat gcgatgcgca
     8521 taacgccgcg ataccgacgc cagcacgccg taagttgacg ccacacagtt acagcccgct
     8581 tcgatcgcca gttcaacaat gtttttcggg tcaaagtaga gcgggttagc agcaaatgaa
     8641 gctccggcag agtgctcaac gccctggtca accggcagaa tagaaagata tcctgtgcca
     8701 gccagacgcc cggtgttgta caacgtctgc atattacgta acaccgctgg cgggcgatta
     8761 ttgtcaatca ttacgcggtc tacgtagtca tgtccgggga gataaagctg gtcagaagga
     8821 attgtcatac aacggtgctg taaaaggttg tcggcgtctt tgccaagcaa ctgcgcaata
     8881 tctgtcatta ctatgctccc gtaaattccg attggatatc ggctatggat tgtcctggcc
     8941 cgccttttgc gggcaatcat aatcctggtc gttacgggcg agtttttcca tcttttggat
     9001 gttttttcag cgttttctgt tggctcgatt catcagaaaa aatgttagcg cggtcaagtt
     9061 ttcaccgcaa aggtatttaa aaggtattat taagtggtat tgtcatcgcg taccttacat
     9121 tacctgtcat gaaggaatta aaagatgaaa acaacagcaa agctgtcgtt catgatgttt
     9181 gttgaatggt ttatctgggg cgcgtggttt gtgccattgt ggttgtggtt aagtaaaagc
     9241 ggttttagtg ccggagaaat tggctggtcg tatgcctgca cagccattgc ggcgatcctg
     9301 tcgccaattc tggttggctc catcactgac cgctttttct cggcgcaaaa agtgctggcg
     9361 gtattgatgt tcgcaggcgc gctgctgatg tatttcgctg cgcaacagac cacttttgcc
     9421 gggttcttcc cgttactgct ggcctactcg ctaacctata tgccgaccat tgcgctgact
     9481 aacagtatcg cttttgccaa cgtgccggat gtggagcgtg atttcccgcg cattcgtgtg
     9541 atgggcacta tcggctggat tgcctctggt ctggcatgtg gtttcttgcc gcaaatgctg
     9601 gggtatgccg atatctcacc gactaacatc ccgctgctga ttaccgccgg aagttctgct
     9661 ctgctcggtg tgtttgcgtt tttcctgccc gacacgccgc caaaaagcac cggcaaaatg
     9721 gacattaaag tcatgctcgg cctggatgcg ctgatcctgc tgcgcgataa aaacttcctc
     9781 gtctttttct tctgttcatt cctgtttgcg atgccactgg cgttctatta catctttgcc
     9841 aacggttatc tgaccgaagt tggcatgaaa aacgccaccg gctggatgac gctcggccag
     9901 ttctctgaaa tcttctttat gctggcattg ccgtttttca ctaaacgctt tggtatcaaa
     9961 aaggtattat tgcttggtct ggtcaccgct gcgatccgct atggcttctt tatttacggt
    10021 agtgcggatg aatatttcac ctacgcgtta ctgttcctcg gtattttgct tcacggcgta
    10081 agttacgatt tttactacgt taccgcttac atctatgtcg ataaaaaagc ccccgtgcat
    10141 atgcgtaccg ccgcgcaggg gctgatcacg ctctgctgcc agggcttcgg cagtttgctc
    10201 ggctatcgtc ttggcggtgt gatgatggaa aagatgttcg cttatccgga accggtaaac
    10261 gggctgactt tcaactggtc cgggatgtgg actttcggcg cggtgatgat tgccattatc
    10321 gccgtgctgt tcatgatttt tttccgcgaa tccgacaacg aaattacggc tatcaaggcc
    10381 gatgatcgcg atattgcgtt gacacaaggg gaagttaaat gaaaacagaa cgtattctcg
    10441 gtgctcttta tgggcaggcg ttaggggatg cgatggggat gccctccgag ctttggccac
    10501 gcagccgcgt taaagcacac tttggctgga ttgaccgttt tctgcctgga ccaaaggaga
    10561 ataacgcggc ctgttatttt aaccgcgccg aattcaccga cgatacctcg atggcgctgt
    10621 gtctggcgga tgcgttactg gaacgtgaag gcaagatcga tccggatctg attgggcgta
    10681 atattctcga ctgggcgctg cgtttcgacg cctttaacaa aaacgtacta ggtccgacct
    10741 cgaagattgc gcttaacgcc attcgcgacg gtaaacccgt tgctgaactg gaaaacaacg
    10801 gcgtgaccaa cggcgcagcg atgcgcgtct cgccattagg ttgtttgctt ccggcgcgtg
    10861 atgttgattc ctttattgat gatgtggcgc tggcgtcgag cccgacccat aaatccgatc
    10921 tggcagttgc aggtgcggta gtcatcgcat gggcgatttc tcgtgccatt gacggagaaa
    10981 gctggtcagc gattgttgat tccctgcctt caattgcgcg acatgcacag caaaaacgca
    11041 tcactacctt cagcgcctca ctggcagcac gtctggagat tgcgctgaaa attgtgcgca
    11101 atgccgacgg caccgaatcc gccagcgaac agctttacca ggtcgttggc gcaggtacca
    11161 gcactattga gtccgttccg tgcgccattg cgctggttga actggcacaa accgacccga
    11221 atcgctgcgc cgtcctgtgc gctaaccttg gcggcgacac agacaccatc ggcgctatgg
    11281 cgacggcgat ttgcggcgcg ttgcatggcg ttaacgctat cgatcctgca ttaaaggcgg
    11341 aactggatgc ggtaaatcag cttgatttca accgctatgc cacagcgctg gcgaaatatc
    11401 gtcaacaacg ggaggcggta tgagcggcgc tcgattacac acgctgctgc ctgaattaac
    11461 ctcgcgtcag ccggtgatgg tcgtcggcgc ggcggtcatt gatgtgatcg ccgacgctta
    11521 tgccctcccc tggcgtgggt gcgatatcga actgaagcag cagagcgtta acgttggcgg
    11581 ctgcgcactg aatattgccg tggcgttaaa gcgcctcggc atcgaagcgg gtaatgcctt
    11641 gccgctcggt cagggcgtgt gggcggagat tattcgcaac cggatggcga aagaggggtt
    11701 aatcagcctg atcgataacg ccgaaggcga taacggctgg tgtctggcgc tggttgagcc
    11761 ggatggcgaa cgcactttta tgtcattcag cggtgtggaa aatcagtgga atcgccagtg
    11821 gctggcgcga ttaaccgttg cgcctggcag cctgctctat ttttccggtt atcaactggc
    11881 ctcgccctgc ggcgaattgt tagtggaatg gctggaaaag ctgcaagacg tgacgccgtt
    11941 tatcgatttt ggcccacgta tcggcgatat cccggacgca ttactggcgc ggatcatggc
    12001 ctgtcgacct ttagtatcac tcaatcgtca agaggctgag attgccgccg aacgttttgc
    12061 tttatccgca gagataacaa cacttggcaa gcaatggcag gagaaatttg ccgcgccgtt
    12121 gatcgttcgt ctcgataaag agggtgcatg gtatttcagc aacgacgctt ctggctgcat
    12181 tccggcattt ccaacgcaag ttgtagacac cattggggcg ggcgacagtc atgcaggtgg
    12241 cgtacttgcc gggctggcct ctggtctgcc actggcggat gccgtattac tgggcaatgc
    12301 agtggcgtcg tgggttgtcg ggcatcgggg cggtgattgt gcgccaacgc gcgaggaact
    12361 actcctcgca cacaaaaacg tatagatcgc tgcgacagtg gctaatgctg tactcaatag
    12421 gccgttgctg ttggtcaagc gccacttgct tgatcaccag caccggtatt ttgctatcta
    12481 actgaatatg tgactgaaac tcggcatccg gcatccgggc gctaacgcgg gaacgcgtac
    12541 gttgtgggta aatgtgctgg ctgcggaaat agtcataaag tgaaatcccg atggcatcaa
    12601 catcatgaat taaatgcgcc ggaacccacg attcctcaat cgataccgct tcttcatcga
    12661 catagcgaat acgcttaagc aaaaagacat cacttcctgc ttcgaccgcc agctgctgcg
    12721 cgacttcttc gggacatttc acgacacgct tgttaaccca tagcgtatcg ggctttttcc
    12781 cgcgcaatac cacctgctga gaaaaacctc gcgcttcttt caacgagtat tcgaagatgt
    12841 tgttgatctg cgtgccgtaa ccgcgcgaac gcgtcaccac accctcttct tccagcgcct
    12901 gcatcgcctt gcgcaccgta atgcgcgaaa cgccggttaa ctgacttaaa tcacgctcac
    12961 cgggcaaaat attgccatgc tccagcaccc cgctgcgcac ggcatttttt accgtttcgg
    13021 caaacttaat ataaagcggc gtgttatccg ccgctaaaat acgctcgttc agttgggcaa
    13081 tcagctgggt atgcgcttgt tccatttgtc tttttcctgc cgaggagtct ggtgggagta
    13141 tatcactgct tcttatttaa ggcgtttctt taatcccatc aacgaatgcc tgcaactcct
    13201 ccaccgtgcc atgaaataca ttaaaatcca ccggaccatt gatgccatct acctgtccac
    13261 ggtcggaatg ctgccagaag cgccaggcca tgccgtcatt gtccggacga cgttgataat
    13321 agtgagccac ccaccacgga tattcattga aatagcccgc cagattggtg tgataaaaaa
    13381 cggctcctga gtaaataatc ggcttttttc ccgtactttt ttcgaccatt tttagccact
    13441 gacttactcg tttgcgtaat tcttttgccg ataattttcc ccgttcttct acgtccagta
    13501 ccgcagggaa atcgccttgt gagaaatcca ccgtttgcag aaataatcgt gcctgaaccg
    13561 gcgctgctac cgacggggag aaataatgat acgccccgcg cagcaggcca ttttcgcggc
    13621 ttagttgcca gttacgcgaa aaatacgggt ccaccagctt ttcgccttcc gtcgccttaa
    13681 taaataaaag caaactgtaa gcggataccg ttgtcgcgca tttttgccac ccgctgccag
    13741 tcgatccgct cctgccagcg agaaacatct attccgtgaa tggtgtaact ggcaggaatg
    13801 cgaatagcga aagatttaac cgggcgataa ccgtagaaat ggatgtagtc tgtaatctga
    13861 actgctgtcg aatagaaaaa attcaccgtc tgacgcggat aaattgcaac gatggaaatt
    13921 agcccaagag cgcataatag agaggtgagt ttttttcgac tggtaattct tagctgcatt
    13981 ggtttcatcc ctgaatgtca gtgccaaagg ctgacaataa ccaaagcagc tatagtacgg
    14041 tgctcaccac caggcgtgga agtggtgaac cggaccaata ccgtgaccaa cttccagcgt
    14101 gtcggcctgg gctaatgctg atgaaagcca gctttttgcc tcctgtacgg tgtcagccca
    14161 gtttgtatgg cgcgggcgta gtgcagccaa cgccgcagag agcgtacaac cagtgccgtg
    14221 ggtgtttttg gtcataatgc gcggtgcggt aaaccgttgt tcaccctcgc gggtaaacag
    14281 ccagtccggg ctttgctcat catccagatg accacctttc attagcactg cgccacagcc
    14341 catcgccaac agcgatcgcc cttgttccag catttcctgt tcggtgcgcg cgtgtggcgc
    14401 gtcgagcaag gcggcagctt cgggcaagtt tggcgttatt aatgaaacct gtggcaataa
    14461 tcgactgcgc agcgtagcaa ccgccgaagg tgaaagcagc gggtcgccgc tttttgccag
    14521 cataacggtg tcgagtacca cgttttggat ctgataacgt tgcaaccgtt ctgccaccgc
    14581 ttcaacaata tcggtttccg ccaacatacc gattttagtg gtgtcgattc gcacatcgct
    14641 gaacaccgaa tcgagctggg cggcgacaaa atcaggctca atgcgataca ccgactgtac
    14701 gccacgggta ttttgcgcca ccagtgcagt aataactgag caaccataag cgccaagtgc
    14761 cgagaaggtt ttaagatcgg cctgaatccc cgcaccacca ctgggatcag taccggcaat
    14821 cgtcagagcg ttaattcgtt tcatgcctgc acctcctgcg tcaattgcca gagcgcatca
    14881 aggaaatgtg gaacaaaact gcctggcccc tcgcttctgg cgactgcgcg ctctccggct
    14941 tgtttcatcc agtgacaggc agatgcgaca ttttccagcg tatcgcctgg taacgcacag
    15001 caggcagcga caaccgccga taatgcacag ccagttccta ccactttggt cattaacgga
    15061 tcgccaccgt gaatgccaac ggcgcgatgg ccatcggtaa cataatccac ctcgccagtg
    15121 accacgacga ttgcgccagt ttcccgtgcc agtgtttgtg cagcgggtat cgcgttagct
    15181 gcggcgtcag tggtatccac tccccgtcca ccattagcaa tgccagctaa tgccatgatt
    15241 tccgaagcat taccacgtat cgctgccggt ttaaaagata aaagttcatg acaaaaatgg
    15301 cggcgataat cgagcgcacc aaccgctact ggatcaagcg tccagggtgt ttgagagctt
    15361 tttgcttgct caacggcagc acgcatcgcc tgagcgcgtg gctgcgtcag tgtgccaacg
    15421 ttaatcaaca aggcactggc gatagccgca aactgactgg cctcttcggt ttcgataacc
    15481 atcgctggcg atgcaccgag cgccagcaag gtattggcag taaaggtttg caccacatcg
    15541 ttggtcatgc agtgcacaag aggggaatgt tggtgaaaaa ggtgtaacgc gtgcgcagat
    15601 tgcgctgaac tcagcaggtc gacttgcata gtttgctcct gccataacgt gaagaagcaa
    15661 tgacctggtg gtccgtgact tccctacgct ggcattatcc agatcaggtg atacgggtat
    15721 ttctcagcct tcacgcagaa gggcaccccg agtcgtttgg ttgcgatgat aaatcgcaga
    15781 ggaggatggt aatgtccagc gcacgcgttg taaacgagga aaaacggcag ttttacaatc
    15841 gcgttaataa attatttgat atatgaatcc agcaccttca gaacgacatc cagatcttct
    15901 tcacgtttta gctcatcccc ctggtgaacg atgtgttccg tcagatgacc tttaatcact
    15961 tcccgcatca gaccgtttac cgcgccacgg atagcagcaa tctgttgtaa aactgcagcg
    16021 cattcgtgcg gctcgtcgag cattttcttg agcgccacga cctggccctg aatcttactg
    16081 gcacgcgctt tcagtttctg tttatcacgg attgtatgag acatggcaac acctggttaa
    16141 caagaatatg aaaaatcata gcactattaa tctactgggg ggtagtatca ggtactgggg
    16201 gggagtagaa tcagattgcc gaattaatac taagaattat tatcatgacc gaatttacaa
    16261 ctcttcttca gcaaggaaac gcctggttct tcatccccag cgccatctta cttggtgcgc
    16321 ttcatggcct ggaaccaggg cactcaaaaa cgatgatggc ggcgtttatc atcgccatca
    16381 aaggcaccat taaacaggcg gtgatgctcg gactggcagc aactatttcg cataccgcag
    16441 tggtctggtt aattgccttt ggcgggatgg tgatcagcaa gcgctttact gctcaatcag
    16501 cagaaccgtg gctccagctg atttccgcag tgatcattat tggcaccgcg ttctggatgt
    16561 tctggcgtac ctggcgcggc gaacgcaact ggctggagaa tatgcacgag tatgatcatg
    16621 aacatcatca ccacgatcac gaagatcacc acgaccatgg acatcatcac catcacgaac
    16681 atggcgagta tcaggatgcc catgcacgag cccatgccaa tgatattaaa cgacgctttg
    16741 atggtagaga ggtcaccaac tggcaaattt tgttatttgg cttaacaggt ggtcttatcc
    16801 cctgtccggc agcaattacc gtgctgttga tttgcattca gttgaaagcc ctgacactgg
    16861 gcgcaacact ggtcgtcagt ttcagcattg gcctggcgtt aacgcttgtc accgtaggcg
    16921 ttggcgcagc aatcagcgtt cagcaggtcg caaaacgctg gagcggattt aacactctcg
    16981 ctaaacgcgc cccctatttt tccagtctgt tgattggctt agtcggtgtg tatatgggcg
    17041 tacatggctt catgggcata atgcgataac tcaatccttt aggcttgcat gttatcttca
    17101 gcccaggatg attcttaaat cagctatttc cgctgactct ctgctcgcta aggatgcttt
    17161 tagggcatcc tttcatttac actttttacg aaatcatggg atcactaaca aaatatcgct
    17221 tgtcagttat attgtatggc aggaaagata tgcgactgat attacagatc cccaaagtgg
    17281 agagtttatg accattaaaa ataagatgtt gctgggtgtg cttttgctgg ttaccagtgc
    17341 cgcctgggcc gcaccagcca ccgcgggttc gaccaatacc tcgggaattt ctaagtatga
    17401 gttaagtagt ttcattgctg actttaagca tttcaaacca ggtgataccg tcccagagat
    17461 gtaccgcacc gatgagtaca acattaagca gtggcagtta cgtaacctgc ccgcgcctga
    17521 tgccgggacg cactggacct atatgggtgg cgcgtacgtg ttgatcagcg acaccgacgg
    17581 taaaatcatt aaagcctacg acggtgagat tttttatcat cgctaaaaaa agccccctca
    17641 tcatgagggg gaaatgcaga caccttgtta ttttttatta ttagccactt gctcgtcttg
    17701 cttgttatta gtcgtatttc acgttgatta atgcggttgc ctccagtgcg ccagatttaa
    17761 ttttatttgt atcgtagacg tagtaactgg ctgttatcgg aattgaaacc gttgtatctg
    17821 taagttttga ctttgccgca atttctttta aatttgtgta tcctttactg ctgttagtga
    17881 tatttaaaag tgtgactggc gaaccattac tttcaagaat aaatcctacg ccattatctt
    17941 ccgcaccttt cagtattgtg ttgctgttgg ttaacaagtc agaacttgat aaatacacct
    18001 gcattttccg tgatgtttga ttttgttgac ctaataaatt tt
//
LOCUS       DAPGUL010000088        17971 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.089, whole genome shotgun sequence.
ACCESSION   DAPGUL010000088 DAPGUL010000000
VERSION     DAPGUL010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17971)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17971)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17971
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.089"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            29..736
                     /locus_tag="RHX21_003260"
     CDS             29..736
                     /locus_tag="RHX21_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
                     /protein_id="HDV1988410.1"
                     /translation="MNKEEQYLLFALSAPMEILNQGCKPAHDSPKMYTGIKEFDLSSS
                     WGINNRDDLIQTIYQMTDDGHANDLAGLYLTWHRSSPEEWKALIAGGSERGLIYTQFV
                     AQTAMCCGEGGIKAWDYVRMGFLSRVGVLNNWLTEEESLWLQSCVYVRAHHYYHSWMH
                     YFSAYSLGRLYWQSSQCEDNTSLREALTLYKYDSAGSRMFEELAAGSDRFYATLPWQP
                     LTVQPECPVTLKDVSDL"
     gene            733..2184
                     /gene="djlC"
                     /locus_tag="RHX21_003261"
     CDS             733..2184
                     /gene="djlC"
                     /locus_tag="RHX21_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone DjlC"
                     /protein_id="HDV1988411.1"
                     /translation="MKTCWQILEIESTTQIDIIRQAYLARLPLCHPETDPQGFKALRQ
                     AYEEALRLAVNPVEEADDEEKDAAAEHEILRAFRTLLDSESDRFQPSAWQKFIQQLNT
                     WNMEDVDQLRWPLCAIAIEARYLSLNCASLLAERLNWHSFNDSEGMDEEEREAFLEAI
                     QAGDCFDFLSLLEYPVALQNQTVEYYFALERCCRYHPDYVTAFLAMEGPWFIPDDAKL
                     HRKLLRWYSSVQTGMAELIPVAKQWQMEEPESEDARYYLCAQRLYCGEGESLLADLCA
                     YRESYPSTQADNLLLQWSKRHCPDYFALLVMVIEARSMVDAQGQPLKYVPGESARTRL
                     LWAEILHSGKLSPLGQSFIESLFFKRKAWAWWKSRVGSETEEDSPLLDLYRVAEQVVL
                     EAFPKQEMLARLNTRLEGGDAHPLEAIITRLLLTKVKLEPEDEDVDEPTPENHEEKND
                     EGEKPQSITSIIKISLTVLVIGYALGKIAMLFS"
     gene            complement(2244..3914)
                     /gene="hscC"
                     /locus_tag="RHX21_003262"
     CDS             complement(2244..3914)
                     /gene="hscC"
                     /locus_tag="RHX21_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000367910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HscC"
                     /protein_id="HDV1988412.1"
                     /translation="MDNAELAIGIDLGTTNSLIAVWKDGAAQLIPNKFGEYLTPSIIS
                     MDENNHILVGKPAVSRRTSHPDKTAALFKRAMGSNTNWRLGSDTFNAPELSSLVLRSL
                     KEDAEEFLQRPIKDVVISVPAYFSDEQRKHTRLAAELAGLNAVRLINEPTAAAMAYGL
                     HTQQNTRSLVFDLGGGTFDVTVLEYATPVIEVHASAGDNFLGGEDFTHMLVDEVLKRA
                     DVARTTLNESELGALYACVEAAKCSNQSPLHIRWQYQDETRECEFYENELEDLWLPLL
                     NRLRVPIEQALRDARLKPSQIDSLVLVGGASQMPLVQRIAVRLFGKLPYQSYDPSTIV
                     ALGAAIQAACRLRSEDIEEVILTDICPYSLGVEVNRQGVSGIFSPIIERNTTVPVSRV
                     ETYSTMHPEQDSITVNVYQGENHKVKNNILVESFDVPLKKTGAYQSIDIRFSYDINGL
                     LEVDVLLEDGSVKSRVINHSPVTLSAQQIEESRTRLSALKIYPRDMLINRTFKAKLEE
                     LWARALGDEREEIGRVITDFDAALQSNDMARVDEVRRRASVYLAIETS"
     gene            complement(3998..4933)
                     /gene="rihA"
                     /locus_tag="RHX21_003263"
     CDS             complement(3998..4933)
                     /gene="rihA"
                     /locus_tag="RHX21_003263"
                     /EC_number="3.2.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-specific ribonucleoside hydrolase
                     RihA"
                     /protein_id="HDV1988413.1"
                     /translation="MALPILLDCDPGHDDAIAIVLALASPELDVKAITSSAGNQTPEK
                     TLRNVLRMLTLLNRTDIPVAGGAVKPLMRELIIADNVHGESGLDGPALPEPTFAPQNC
                     TAVELMAKTLRESAEPVTIVSTGPQTNVALLLNSHPELHSKIARIVIMGGAMGLGNWT
                     PAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHVEDTERFRAIGNPVSTIVAE
                     LLDFFLEYHKDEKWGFVGAPLHDPCTIAWLLKPELFTSVERWVGVETQGKYSQGMTVV
                     DYYYLTGNKPNATVMVDVDRQGFVDLLADRLKFYA"
     gene            complement(5051..5776)
                     /gene="gltL"
                     /locus_tag="RHX21_003264"
     CDS             complement(5051..5776)
                     /gene="gltL"
                     /locus_tag="RHX21_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter ATP binding
                     protein GltL"
                     /protein_id="HDV1988414.1"
                     /translation="MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLI
                     KTVNGLEPVQQGEITVDGIVVNDKKTDLAKLRSRVGMVFQHFELFPHLSIIENLTLAQ
                     VKVLKRDKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF
                     DEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIVEDS
                     PKDAFFDDPKSDRAKDFLAKILH"
     gene            complement(5776..6450)
                     /gene="gltK"
                     /locus_tag="RHX21_003265"
     CDS             complement(5776..6450)
                     /gene="gltK"
                     /locus_tag="RHX21_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter permease
                     GltK"
                     /protein_id="HDV1988415.1"
                     /translation="MYEFDWSSIVPSLPYLLDGLVITLKITVTAVVIGILWGTMLAVM
                     RLSSFAPVAWFAKAYVNVFRSIPLVMVLLWFYLIVPGFLQNVLGLSPKNDIRLISAMV
                     AFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLT
                     QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLSASLLVSY
                     LKRRTA"
     gene            complement(6450..7190)
                     /gene="gltJ"
                     /locus_tag="RHX21_003266"
     CDS             complement(6450..7190)
                     /gene="gltJ"
                     /locus_tag="RHX21_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter permease
                     GltJ"
                     /protein_id="HDV1988416.1"
                     /translation="MSIDWNWGIFLQQAPFGNTTYLGWIWSGFQVTIALSICAWIIAF
                     LVGSFFGILRTVPNRFLSGLGTLYVELFRNVPLIVQFFTWYLVIPELLPEKIGMWFKA
                     ELDPNIQFFLSSMLCLGLFTAARVCEQVRAAIQSLPRGQKNAALAMGLTLPQAYRYVL
                     LPNAYRVIVPPMTSEMMNLVKNSAIASTIGLVDMAAQAGKLLDYSAHAWESFTAITLA
                     YVLINAVIMLVMTLVERKVRLPGNMGGK"
     gene            complement(7360..8268)
                     /gene="gltI"
                     /locus_tag="RHX21_003267"
     CDS             complement(7360..8268)
                     /gene="gltI"
                     /locus_tag="RHX21_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter
                     substrate-binding protein GltI"
                     /protein_id="HDV1988417.1"
                     /translation="MQLRKPATAILALALSAGLAQADDAAPVAGSTLDKIAKNGVIVV
                     GHRESSVPFSYYDNQQKVVGYSQDYSNAIVEAVKKKLNKPDLQVKLIPITSQNRIPLL
                     QNGTFDFECGSTTNNVERQKQAAFSDTIFVVGTRLLTKKGGDIKDFADLKGKAVVVTS
                     GTTSEVLLNKLNEEQKMNMRIISAKDHGDSFRTLESGRAVAFMMDDALLAGERAKAKK
                     PDNWDIVGKPQSQEAYGCMLRKDDPQFKKLMDDTIAQVQTSGEAEKWFDKWFKNPIPP
                     KNLNMNFELSDEMKALFKEPNDKALN"
     gene            8723..10600
                     /locus_tag="RHX21_003268"
     CDS             8723..10600
                     /locus_tag="RHX21_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HDV1988418.1"
                     /translation="MSASSVKPLNVQLPAITLILFALCVGIFCYLAQWMSYEEVDQSA
                     LIHLGANVASLTLSGESWRLFSSVFLHSSFSHLLMNMFALLVVGAVAERILGKWRLLI
                     IWLFSGVFGGLISACYALRDSDQIVISVGASGAIMGIAGAALATQLASGAGTYHKNQR
                     RVFSLLGMVALTLLYGARQAGIDNACHIGGLIAGGAMGWQRARLSGQNRLVTEGGIIV
                     AGSLLLTGAIWLAQQQIDESVLQVRQSLREEFYPQEIEQERRQKKQQLAEERNALRET
                     LSAPVSREQASGDLLAEIADIHDMAISRDGNTLYAAIEDTNSIVVFDLGQKKILHTFT
                     APIAKEKSVKHCGGCKDQGVRSLALSPDEKLIYATSFEANALSVINVATGEIIQSITT
                     GAHPDSLILSRDGTKAWVMNRTSNSVSAIDLVTYQHVADIPLEKYDGTGTSNKPGAWV
                     MALSPDEKILLIPGMVRGDIVRINTITHQKESYPASDARGTISAMRFRPENGDVIFAD
                     SQGISRISVGDQQASIMTQWCSRSVYSVEGISPDGQYLALVSYGLQGYVILLNINAGQ
                     IIGVYPASYVNHLRFSADGRKIFVMAKNGLIQLDRTRSLDPQAIIRHPQYGNVACIPE
                     P"
     gene            complement(10678..12216)
                     /gene="lnt"
                     /locus_tag="RHX21_003269"
     CDS             complement(10678..12216)
                     /gene="lnt"
                     /locus_tag="RHX21_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="apolipoprotein N-acyltransferase"
                     /protein_id="HDV1988419.1"
                     /translation="MAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIISLMGL
                     QALTFNRRPLQSAAIGFCWGFGLFGSGINWVYVSIATFGGMPGPVNIFLVVLLAAYLS
                     LYTGLFAGVLSRLWPKTTWLRVAIAAPSLWQVTEFLRGWVLTGFPWLQFGYSQIDGPL
                     KGLAPIMGVEAINFLLMMVSGLLALALVKRNWRPLVVAVVLFALPFPLRYIQWFTPQP
                     EKTIQVSMVQGDIPQSLKWDGDQLLNTLKIYYNATAPLMGKSSLIIWPESAITDLEIN
                     QQPFLKALDGELRDKGSSLVTGIVDARLNKQNRYDTYNTIITLGKGAPYSYESADRYN
                     KNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPPLSVNGIELTAAICYEIIL
                     GEQVRDNFRPDTDYLLTISNDAWFGKSIGPWQHFQMARMRALELARPLLRSTNNGITA
                     VIGPQGEIQAMIPQFTREVLTTNVTPTTGLTPYARTGNWPLWVLTALFGFAAVLMSLR
                     ARKR"
     gene            complement(12241..13119)
                     /gene="corC"
                     /locus_tag="RHX21_003270"
     CDS             complement(12241..13119)
                     /gene="corC"
                     /locus_tag="RHX21_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308723.1"
                     /note="CorC(YbeX) belongs to the Cyclin M Mg2+ Exporter
                     (CNNM) family, and was characterized as belonging to a set
                     of three proteins, at least one of which must be present
                     for CorA to function; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CNNM family magnesium/cobalt transport protein
                     CorC"
                     /protein_id="HDV1988420.1"
                     /translation="MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDS
                     GQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSR
                     FPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRS
                     QRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALA
                     SIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQ
                     VHVKIPDDSPQPKLDE"
     gene            complement(13209..13676)
                     /gene="ybeY"
                     /locus_tag="RHX21_003271"
     CDS             complement(13209..13676)
                     /gene="ybeY"
                     /locus_tag="RHX21_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014169133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HDV1988421.1"
                     /translation="MSQVILDLQLACEDNSGLPEESQFQTWLNAVIPQFQEESEVTIR
                     VVDTAESHSLNLTYRGKDKPTNVLSFPFEVPPGMEMSLLGDLVICRQVVEKEAQEQGK
                     PLEAHWAHMVVHGSLHLLGYDHIEDDEAEEMEALETEIMLALGYEDPYIAEKE"
     gene            complement(13673..14713)
                     /locus_tag="RHX21_003272"
     CDS             complement(13673..14713)
                     /locus_tag="RHX21_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415193.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HDV1988422.1"
                     /translation="MNIDTREITLEPADNARLLSLCGPFDDNIKQLERRLGIEINRRD
                     NHFKLTGRPICVTAAADILRSLYVDTAPMRGQIQDIEPEQIHLAIKEARVLEQSAESV
                     PEYGKAVNIKTKRGVIKPRTPNQAQYIANILDHDITFGVGPAGTGKTYLAVAAAVDAL
                     ERQEIRRILLTRPAVEAGEKLGFLPGDLSQKVDPYLRPLYDALFEMLGFEKVEKLIER
                     NVIEVAPLAYMRGRTLNDAFIILDESQNTTIEQMKMFLTRIGFNSKAVITGDVTQIDL
                     PRNTKSGLRHAIEVLADVEEISFNFFHSEDVVRHPVVARIVNAYEAWEEAEQKRKAAL
                     AAERKREEQEQK"
     gene            complement(14866..16290)
                     /gene="miaB"
                     /locus_tag="RHX21_003273"
     CDS             complement(14866..16290)
                     /gene="miaB"
                     /locus_tag="RHX21_003273"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HDV1988423.1"
                     /translation="MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVL
                     LLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDII
                     FGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKY
                     CTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGSF
                     ADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNL
                     MGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTEDFEKTMKLIADVNFDMSY
                     SFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGT
                     SRKSIMELSGRTENNRVVNFEGTPDMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRV
                     AETPESVIARTRKENDLGVGYYQP"
     gene            16436..17611
                     /gene="ubiF"
                     /locus_tag="RHX21_003274"
     CDS             16436..17611
                     /gene="ubiF"
                     /locus_tag="RHX21_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706550.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol
                     hydroxylase"
                     /protein_id="HDV1988424.1"
                     /translation="MTNQPTEIAIVGGGMVGGALALGLAQHGFSVTVIEHAEPAPFVA
                     DSQPDVRISAISAASVSLLKGLGVWDAVQAMRCHPYRRLETWEWETAHVMFDAAELKL
                     PLLGYMVENTVLQQALWQALEAHPKVTLRVPGSLIALHRDNDLQELELKGGEVIRAKL
                     VIGADGANSQVRQMAGIGVHAWQYAQSCMLISVQCENDPGDSTWQQFTPDGPRAFLPL
                     FDNWASLVWYDSPVRIRQLQNMNMAQLQAEIAKHFPSRLGYVTPLAAGAFPLTRRHAL
                     QYVQPGLALVGDAAHTIHPLAGQGVNLGYRDVDALIDVLVNARSYGEAWASYPVLKRY
                     QMRRMADNFIMQSGMDLFYAGFSNNLPPLRFVRNLGLMAAERAGVLKRQALKYALGL"
     gene            complement(17765..17839)
                     /locus_tag="RHX21_003275"
     tRNA            complement(17765..17839)
                     /locus_tag="RHX21_003275"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17805..17807),aa:Gln,seq:ctg)
     gene            complement(17888..17964)
                     /locus_tag="RHX21_003276"
     tRNA            complement(17888..17964)
                     /locus_tag="RHX21_003276"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17928..17930),aa:Met,seq:cat)
BASE COUNT         4380 a         4496 c         4668 g         4427 t
ORIGIN      
        1 gttaatgcac ttaagggatt attaacaaat gaataaggaa gaacaatatc ttctttttgc
       61 gctttctgcg cccatggaaa tacttaatca gggttgcaaa cccgcgcatg actcgccaaa
      121 aatgtatacc gggataaaag aattcgatct ctcatcatcc tggggaataa ataatcgtga
      181 tgatttaatt cagactattt atcagatgac tgatgatggt catgccaatg atttagctgg
      241 cttatatctg acatggcatc gctcttcccc tgaagagtgg aaagcattaa ttgctggtgg
      301 ctcggagaga gggttgattt atacccaatt cgttgcccaa accgctatgt gctgtggaga
      361 agggggaatc aaagcctggg attatgttcg aatggggttt ctgtcacggg tcggtgtgct
      421 caacaactgg ctgacggaag aagagagttt atggctgcaa tcgtgcgtct atgtacgagc
      481 tcaccattac tatcacagct ggatgcacta tttttccgcc tattcgttag gacgtctcta
      541 ctggcaatct tctcagtgcg aagacaacac ttcgctacgc gaggcgctaa ccctgtacaa
      601 atacgatagc gccgggagtc ggatgttcga agagctggca gcgggaagcg atcgtttcta
      661 tgccacgctt ccctggcagc cattaactgt ccagcctgaa tgcccggtaa cgcttaagga
      721 tgtgagcgac ctatgaaaac atgttggcaa atcctcgaaa ttgaaagcac gacgcaaata
      781 gacattatcc gccaggctta tcttgctcgc ttaccgttat gtcatcccga aaccgatccg
      841 caggggttta aagcattacg ccaggcctat gaagaggcgc tgcgactggc ggtaaatcct
      901 gtcgaggaag cagatgatga agaaaaagat gccgccgctg aacatgaaat actgcgtgca
      961 ttcaggacat tactggattc agaaagtgat cgttttcagc cctccgcctg gcagaaattt
     1021 attcagcaat taaatacctg gaacatggag gatgtcgatc aattacgctg gccgctgtgt
     1081 gcaatcgcta tagaagcgcg atatctttca ttaaattgtg cttctttgct ggcagagcgt
     1141 ttgaactggc attcgtttaa tgacagcgaa ggaatggatg aggaagaaag ggaggctttt
     1201 cttgaggcca ttcaggctgg tgattgtttc gatttcctta gccttctgga atatcccgtt
     1261 gcgttgcaga accagactgt tgagtattac ttcgcgctgg aacgttgctg ccgttaccat
     1321 cctgactacg tcactgcgtt tttggcgatg gaaggtccgt ggttcattcc tgatgatgca
     1381 aagttacatc gcaaactgtt gcgctggtac agctcggtgc aaacaggtat ggcggaactc
     1441 attcctgtag ccaaacagtg gcaaatggaa gaaccagaaa gcgaagatgc ccgatattac
     1501 ttgtgtgctc aaaggttgta ctgcggcgag ggggaaagcc tgcttgccga tctctgcgcg
     1561 taccgggaaa gttacccatc tacacaagct gataatttgt tgttgcagtg gagcaagcgt
     1621 cattgcccgg attatttcgc gttattagtg atggttatcg aagcgcggag catggtagat
     1681 gcgcaaggtc aaccgctgaa atatgttcct ggtgagagcg cccggacgcg gctgttatgg
     1741 gcggaaattt tacatagcgg aaaattatcg ccgttaggtc aatcgtttat tgagtcgtta
     1801 ttcttcaaac gcaaagcatg ggcgtggtgg aaatcgagag tcggtagcga gacagaagaa
     1861 gattcaccgt tactggattt gtatcgggta gcggaacagg tagtacttga agcgtttccg
     1921 aaacaagaga tgctggcccg tcttaataca aggctggaag gcggagatgc tcatccatta
     1981 gaggccatta tcacccggtt gctgttgacg aaagtaaaac tcgagccgga ggatgaagat
     2041 gtcgatgagc caacacctga aaaccatgaa gaaaaaaatg atgagggtga aaaaccacag
     2101 agcattacca gcattatcaa aatcagttta acggtgctgg ttataggtta tgctctcggc
     2161 aaaatcgcga tgttgtttag ttgacgatgt gttttttgcg ccgatgccgg atgcagcatt
     2221 tacgccgcat ccggcagccg tgattatgag gtctcaatgg ctaaataaac gctcgcccgc
     2281 cgcctgacct catcgacgcg ggccatatcg tttgactgca gcgccgcatc aaaatcggtg
     2341 atcacccggc caatctcttc tcgctcgtca cccagcgccc gcgcccacaa ctcttccagt
     2401 ttggctttaa aggtgcgatt gatgagcata tcgcgcggat aaattttcaa tgcggataac
     2461 cgcgtccgac tctcttcaat ctgctgcgcg ctcaatgtta ccgggctgtg gttaatcact
     2521 ctggacttaa cgctgccgtc ttccagaagc acgtcaactt caagcaaccc gttgatatca
     2581 taactaaagc gaatatcaat cgactgataa gccccggttt tcttcaacgg cacatcgaag
     2641 gattccacca gaatgttgtt tttaactttg tggttttctc cctgatagac gttaaccgta
     2701 attgaatcct gttccgggtg catggttgaa taagtttcta cacgcgacac gggcacagtg
     2761 gtgtttcgtt caataatcgg cgagaaaatg ccggaaacgc cctggcggtt aacttcaacg
     2821 cccaacgagt aagggcaaat atcagtgagg attacctctt caatatcttc actgcgtaag
     2881 cggcaggcgg cctggattgc tgcgcccagc gcgacaatgg tgctcggatc gtaactttga
     2941 tacggtaatt tgccaaacag acgcacggcg attcgctgca ccagcggcat ttgtgacgcg
     3001 ccgccaacca gcaccagact gtcgatttga ctcggcttca gacgtgcatc gcgcaacgcc
     3061 tgttcaatcg gcactcgcaa gcgattgagc agcggcaacc acaaatcttc cagttcgttc
     3121 tcgtaaaatt cgcactcccg cgtttcatcc tggtactgcc agcgaatgtg caatggcgat
     3181 tgattgctac attttgccgc ttccacacag gcgtacaagg ctcccagttc actctcgtta
     3241 agcgtggtcc tggcgacatc cgcgcgtttt aaaacctcat cgaccagcat atgggtaaaa
     3301 tcttcgccac caagaaagtt gtcgccagcg gaggcgtgaa cttcaatcac cggcgtggcg
     3361 tactcaagca ccgtaacgtc aaacgtgccg ccaccgagat caaacaccag cgaacgggta
     3421 ttttgttggg tatgcaggcc atacgccatc gcagctgctg tgggttcatt aattaagcgt
     3481 accgcattta acccggctaa ctccgctgct aaacgggtat gcttgcgttg ttcatcgctg
     3541 aaataagccg gaacggagat caccacatct ttaatcggac gttgcagaaa ttcttcggca
     3601 tcttctttta atgagcgtaa taccaaagag gacagttctg gcgcgttaaa tgtgtcgctg
     3661 cctaaccgcc agttggtatt actgcccatt gcacgtttaa ataacgctgc cgttttatcc
     3721 ggatgcgaag tacgccgtga tacagccggt tttccgacta aaatatgatt attttcatcc
     3781 atgctaatta tggatggtgt taaatattca ccgaacttat ttggaattaa ttgcgcggca
     3841 ccgtctttcc agacggcaat taaactattg gtagtgccga gatcgatacc aatggcgagt
     3901 tctgcattat ccattgcatt tatatcttga aagaaaaaga gataaacaga ttaagaccac
     3961 ccaggtaacg cgtggtgatc ttaatcaatg acgtgtgtta agcgtaaaat ttcagacgat
     4021 cagccagtaa atcaacaaag ccctgacgat caacatcgac cattacagtg gcattcggtt
     4081 tattgccagt cagataataa taatcaacaa ccgtcatacc ctggctatat ttcccctgtg
     4141 tttccacgcc aacccagcgc tcaacagagg taaacaactc gggtttcaac agccaggcga
     4201 tggtgcatgg gtcatgcagc ggtgcaccga caaagcccca tttttcgtct ttatgatatt
     4261 cgaggaagaa atccagcagt tcggcaacaa tggttgaaac agggttgcca atcgcgcgga
     4321 aacgctcggt gtcttcaacg tggatttgtg ctttgtgagt aacatccaga ccggccatca
     4381 ccactgggat ccctgactgg aagacaattt ctgccgcttc cgggtcaacg taaatattaa
     4441 attcagccgc aggcgtccag ttaccaagcc ccattgcgcc gcccataatc acgatacggg
     4501 caattttgct atgcagttcc ggatggctat tgagcagcaa ggcaacgtta gtttgcggtc
     4561 cggtagacac aatcgtgaca ggttccgcac tttcgcgcag cgttttcgcc atcagctcta
     4621 ccgccgtaca gttttgcggt gcgaacgtcg gttccggtaa tgccgggcca tccagaccgc
     4681 tttcgccgtg cacattgtcc gcgataatca actcacgcat taacggtttt accgcgccgc
     4741 ctgctaccgg aatatcggtg cgattaagca aggtcagcat acgaagaaca ttgcgtaagg
     4801 ttttttctgg tgtctggttt ccggcggaag acgtaattgc tttgacatca agctctggtg
     4861 aggcgagggc gagaactatt gcgatagcgt cgtcatgacc tgggtcgcaa tctaacagaa
     4921 ttggcagtgc cattgttgct ccttgttgtg tgcttctttg cgacaagggt aacgccagga
     4981 tgtaacagat acgaggggcg aaacgataaa gcgtgagatg gcgcgcactt gggtatgcgc
     5041 gccagagtga ttaatgcagg attttcgcga ggaagtcttt cgcgcggtcc gatttcggat
     5101 catcgaagaa agcgtctttc ggcgagtctt cgacaatttt accctcgtcc ataaagatca
     5161 cccgattcgc cactttacgg gcaaaaccca tttcgtgggt caccaccatc atggtcattc
     5221 cttcgtttgc cagttccacc atcacgtcca gcacttcgtt gatcatctcc ggatccagcg
     5281 ccgatgtcgg ttcgtcgaac agcatcgcaa taggatccat acacaacgcg cgagcgattg
     5341 ccacacgctg ctgctgaccg ccggaaagct gcgccggaaa tttattggca tgtgcggaaa
     5401 gtcccacgcg ctccagcaat ttcaatgctt tttcacgagc gggcgcttta tcgcgtttaa
     5461 gcactttcac ctgcgccagg gtcaggtttt cgataatcga cagatgaggg aacagctcga
     5521 aatgctggaa taccatcccg acgcgggaac gcagctttgc cagatcggtt ttcttgtcat
     5581 taaccacgat accatcgacg gtgatttcac cttgctgcac tggttcgagg ccgttgacgg
     5641 ttttaatcag cgttgatttg ccggaaccag acgggccgca aaccaccacc acttcgcctt
     5701 ttttcacttc ggttgagcag tcggtcagca cctgaaagtg accataccat tttgaaacat
     5761 ttttcagggt aatcattatg ctgtccttct tttcaagtag ctgaccaaca acgacgcgct
     5821 aagactaata acgaaataaa caaatccggc aaacaggatc atctcaacct gcgtaccatc
     5881 acgctcacca atggttgagg cggtacggaa gaaatcggcc agagataaca catacaccag
     5941 tgaggtatcc tggaacagta cgatgccctg agtgagcaga agcggcacca tcgcgcggaa
     6001 cgcctgcggc agaataatca gtttcatcga ctgccagtga gtcattccca acgccagcgc
     6061 ggcgctcgac tgaccacgag aaatactttg aataccagca cggataatct ctgaatagta
     6121 ggccgcttca aacatcgaaa acgccaccat cgccgaaatt aaacggatat cattttttgg
     6181 tgataatccc agcacgtttt gcagaaaacc tggcacgatc aggtaaaacc acagcaaaac
     6241 cataactaaa ggaatcgagc ggaatacgtt aacgtaggct ttggcaaacc acgctacggg
     6301 cgcaaagctg gacaagcgca tcaccgccag catggtgccc cacaaaatac caatcacgac
     6361 tgccgtgacg gtgattttca gcgtgatcac cagcccgtcg agcagatatg gcagggaagg
     6421 gacaatggaa ctccagtcaa actcgtacat tatttgcccc ccatgttgcc aggcaggcga
     6481 actttacgtt caaccagcgt cattaccagc atgataaccg cgttaatcaa cacatacgcc
     6541 agcgtaatag cggtaaacga ctcccaggcg tgggctgagt aatcaagcaa tttacccgcc
     6601 tgcgccgcca tatccaccag accaatagtc gaggcgatgg cggagttttt caccaggttc
     6661 atcatctcgg aagtcatcgg cgggacgata acgcgatacg cgttaggcaa cagcacgtat
     6721 cgataagcct gcggtagcgt caggcccatc gccagcgcgg catttttttg cccacgcggc
     6781 aacgactgaa tggcggcgcg tacctgttcg caaacacggg cggcggtaaa cagccccagg
     6841 cagagcatgg atgaaaggaa aaactgaata ttgggatcca gctcggcctt aaaccacatg
     6901 ccgattttct ccggcaacag ctccgggatc accagatacc aggtaaagaa ttgcacaatc
     6961 aacggcacgt tgcggaacag ttcgacatac aacgtaccca gaccggagag aaaacggttt
     7021 ggaacggtac gtaaaatgcc gaaaaatgaa ccgacgagga aagcgataat ccaggcgcag
     7081 atcgacaaag cgatcgtcac ctgaaaacca ctccagatcc aaccaagata ggtggtgttg
     7141 ccgaacgggg cttgttgtaa aaaaataccc cagttccagt ctatagacat aaatctactc
     7201 cagaaaaaag agggtagcag cgttaactgc taccctcgaa gattgttacc cagcgtattg
     7261 cggttttcag gcccgatggg gaacgaccat caggcgtata gtctgtccgt gctacgtaac
     7321 aatcgagagg gctggaattt ccgcccctgg ttcttgtaat tagttcagtg ctttgtcatt
     7381 cggttctttg aacagtgctt tcatttcgtc tgacagttcg aaattcatgt tcaggttttt
     7441 cggcggaatt ggatttttga accatttatc aaaccatttt tccgcttcac cggaagtctg
     7501 cacctgagcg atagtgtcat ccatcagctt tttgaactgc ggatcatctt tacgcaacat
     7561 gcaaccgtag gcttcctgag actgcggctt gccgacgata tcccagttgt ctggtttctt
     7621 cgctttcgca cgttcaccgg ccagcagagc gtcatccatc ataaaggcaa cggcacgacc
     7681 gctttccagg gtacggaaag agtcaccgtg atctttggcg ctaatgatgc gcatattcat
     7741 tttttgctct tcattcagtt tgttgagcaa aacttcagaa gtagtgccgg aagtgacgac
     7801 tacggctttg cctttcaggt cggcaaaatc tttgatatcg ccgccctttt tggtcagcag
     7861 gcgcgtaccg accacgaaaa tagtatcaga gaaagccgcc tgtttttggc gttcgacgtt
     7921 gttggtggta gaaccacatt caaaatcgaa agtgccgttt tgcagcagtg gaatacggtt
     7981 ttgtgaggta atcggaatca gttttacctg caagtccggt ttgttgagtt tctttttcac
     8041 tgcttcaaca atggcgttgg agtaatcctg cgagtaaccc accacttttt gctgattgtc
     8101 gtaataagag aaaggtactg aagattcacg gtgaccgacg acaatcacgc cgtttttggc
     8161 gattttgtcc agcgtactgc ccgctaccgg ggcggcgtca tctgcctgtg ccagtcctgc
     8221 ggaaagcgcc agggcgagga ttgctgtggc aggtttacgt aattgcatat ccaactcctt
     8281 tatcttctgc gttaagaacg catggatacc cgttgtgagt gtttgtgttg ttatcgtctg
     8341 caactttatt gtgcagtgtt gtgcttgtta ggtaacattt agtttggcta aatgtaaaga
     8401 tattgatgtt ttattgtttg tttttgcgag gtgcaccgca ccattccgaa gcaaaattct
     8461 taaaatgcac tcttttggtg ctaccgctga tttgtggtgg tgcaacccgg ttgcgtcgcg
     8521 gctgatttca ttgcttacac agtaaataaa gcaacttaca tgccaaaaaa tacttatggg
     8581 tgaattaatt acgattgtaa tttcaggctg aaaaagtcat atttcggaca gagttatctt
     8641 ttcggcatgg gacgtttgcc gggatgataa ctgcacacgg gaaaaatgct ttttacctgt
     8701 cttttcaagg aagaaacacc ttatgtctgc atcttcggtt aagccgttaa atgttcaatt
     8761 acccgcaata acccttatcc tttttgcgct ctgtgttggg atattttgtt acctcgcaca
     8821 atggatgagt tatgaagaag tcgatcaatc cgcactcatc catctcggtg ctaacgttgc
     8881 ttctctcacg ttgtcgggtg aatcctggcg cttatttagc agtgtctttc tgcacagtag
     8941 tttttcccat ttgctgatga atatgtttgc actcctggtg gtgggggcag tggcggaacg
     9001 gatactggga aaatggcgac ttctgattat ttggttattc tccggcgtct ttggtgggct
     9061 catcagcgcc tgttatgcgt tacgcgatag tgatcagata gtcatcagcg ttggggcgtc
     9121 cggggcaatt atgggaatag ctggcgctgc gttagcaaca cagcttgctt caggtgcggg
     9181 cacataccat aaaaaccagc ggcgagtatt ttctctgttg ggtatggtgg cgctgacact
     9241 gttgtatggt gcccggcaag caggaataga taatgcttgt cacattggcg gcctgattgc
     9301 gggtggcgca atgggttggc agagagcgcg tttatctggg caaaaccggc ttgttacgga
     9361 aggtgggatt attgttgcgg gtagtcttct tctgaccggg gctatctggc ttgcgcagca
     9421 gcagattgat gagtcagttt tacaagtcag gcaaagcctg cgtgaagagt tttatccgca
     9481 ggagattgaa caagagcgac gacaaaaaaa acaacagtta gcggaggaac gcaacgccct
     9541 cagggaaaca ttatccgctc cggtaagtcg tgaacaggcc agtggtgatt tgctcgctga
     9601 gattgccgat atccatgata tggcgatcag tcgggatggt aatacgttgt atgccgcaat
     9661 tgaagacacc aacagcattg ttgttttcga cctcggacaa aagaaaatcc tgcatacctt
     9721 tacagcgccc atagcgaaag aaaagtcagt caaacattgt ggtggctgta aagatcaggg
     9781 cgtcagatcg ctggcattaa gcccggatga aaagttgatt tatgcgactt catttgaagc
     9841 gaatgcgtta tcggtcatta acgtggcgac aggggagatt attcagtcga ttaccaccgg
     9901 tgcacatcct gacagtctta tcctctcgcg tgatggtaca aaagcctggg tgatgaatcg
     9961 caccagtaat agtgtgtcag cgattgatct ggtgacttat cagcatgtgg cggatatccc
    10021 gctggagaaa tacgacggga cggggacgag taataaacct ggtgcctggg ttatggctct
    10081 ttccccggat gaaaaaatat tgttgatacc cggtatggtc agaggtgaca ttgtacgcat
    10141 caataccatc acgcatcaga aagaaagcta tccggctagt gatgcgcgag gaacgatatc
    10201 ggcgatgcgt tttcgacctg aaaacgggga tgtaattttt gccgacagcc aggggatttc
    10261 acgtataagc gtaggggatc aacaagccag cattatgacg caatggtgta gcaggagcgt
    10321 ttattccgtt gagggtatta gcccggacgg tcagtattta gcgttggtgt catatggcct
    10381 gcaaggttat gtcatcctgc tcaatattaa tgccgggcag attattggcg tttatcctgc
    10441 cagctacgtt aatcaccttc gtttttcagc ggatggtaga aaaatatttg ttatggcgaa
    10501 gaacgggttg atccaactgg acaggacgcg ctcgcttgat ccgcaggcaa ttattcgtca
    10561 tccccaatat ggcaatgtgg cttgtatccc tgaaccgtaa gaaaaagggg catgataacc
    10621 atgccccaaa gctcaatgag aaagtacgtt ttgctcatgc aggatacatc aggcacatca
    10681 acgtttacgt gctcgcagac tcatcagcac agcggcaaaa ccaaacagtg ccgtcagcac
    10741 ccacagcggc cagttgccgg tacgtgcgta tggtgtgagt ccggtggtcg gcgtcacatt
    10801 agtggttaac acctcgcggg tgaactgcgg gatcatcgcc tgaatctcac cctgcgggcc
    10861 aatcaccgcc gtaatgccgt tgttggtgct gcgcaacagt gggcgcgcca gctccagcgc
    10921 acgcattcgc gccatctgga agtgttgcca tggaccaata gatttaccaa accacgcatc
    10981 gttggagata gtcagcagat agtcggtatc cgggcggaag ttatcgcgca cttgctcgcc
    11041 aagaatgatc tcgtagcaaa tggccgcagt aagctcaata ccatttaccg acagcggcgg
    11101 ctggatatat ggcccacggc tgaacgacga catcggcaga tcaaagaacg gtgctaacgg
    11161 acgcagaatc gactccagcg ggacaaactc gccaaacggc accagatggt ttttgttata
    11221 gcgatcggct gattcgtagc tgtacggtgc acctttaccc agtgtgatga tggtgttgta
    11281 ggtatcgtag cggttctgct tattgagacg cgcgtcgaca atcccggtta cgagcgagct
    11341 acctttatcg cgcaactcac cgtccagtgc tttgaggaac ggttgctgat taatttccag
    11401 atcggttatc gccgactccg gccagataat caacgatgat ttgcccatca gcggagccgt
    11461 tgcgttgtag taaatcttca gcgtattaag aagctgatct ccatcccatt tcagtgattg
    11521 cggaatatcg ccctgaacca tcgaaacctg aatggttttc tccggttgtg gggtaaacca
    11581 ttggatgtaa cgcagcggga agggtagggc aaacagcacg acggccacca ccagcggacg
    11641 ccagttgcgt ttgaccaacg ccagtgccag caggccacta accatcatca gcaggaagtt
    11701 aatggcttcc acgcccatta tcggtgccag cccttttaac gggccatcaa tctggctata
    11761 gccgaactgt aaccacggga agcctgtcag tacccaaccg cgcagaaact cggtcacttg
    11821 ccagagagaa ggggcggcaa tcgccacgcg cagccaggtg gttttcggcc acagacgcga
    11881 cagcacgcca gcaaacagtc cggtatacag cgacaaatac gccgccagca gcaccaccag
    11941 gaagatgtta accgggccag gcatcccgcc aaaggtcgcg atgctgacat agacccagtt
    12001 aataccgctg ccaaagaggc caaatcccca gcaaaagcca atagcggcag actggagtgg
    12061 acggcggtta aaggtcaacg cctgaagccc catcaacgaa ataatcgccg caggccagac
    12121 gtcgtaagga gagaaggcca gcgttccgca ggcaccgaat aataacgcca gcagcaggcg
    12181 aatgcgctgg cgttcaatta atgaggcaaa agccatgtag ttatctatcc agtttcggtt
    12241 ttattcatcc agcttcggct ggggtgagtc atccgggatt ttgacatgaa cctgaataat
    12301 acgccgactg tcggccatcg ccactttgaa ctggtaaccg tcgatgtcga tagtttcgcc
    12361 acgcgccgga agatgcccaa atgcctgcat caccagacca ccgatagtgt caacctcttc
    12421 atcgctaaag tgggtgccga acgcttcgtt gaagtcttca atggaagcca gtgcgcgcac
    12481 ggtccaggta tgacgactca gctgacggaa gtcgatatca tcttcttcgt catactcgtc
    12541 ttcaatctca ccaacaatta gttccaggat gtcttcaatg gtcaccagac cggaaacccc
    12601 accgaattcg tcaataacga tcgccatgtg gtaacgctga gagcgaaact ctttcagcat
    12661 ccggtctacg cgcttacttt caggaacgac aaccgcctga cgtaacactt tgtccatgct
    12721 gaaggcttca gcatcgctgc gcataaacgg cagcaagtct ttcgccatca gaatcccttc
    12781 aatgtgatct ttgtcttcgc taatcaccgg gaaacgtgag tgggcggact cgatgatgac
    12841 atcaaggcat tcgtccagcg tctggttgcg tttcagggta atcatctggg agcgggggat
    12901 catgatgtcg cgaacgcgtt ggtctgcgat gtccatcacc ccttcgagca tatcgcgcgt
    12961 atcttcgtcg ataaggtcgt tctgcccgga atcacggatc agcgccagca gttcgtcacg
    13021 gtttttcggt tcaccgtgga aaagttggct gagtaacagg gagaaaaatc ccttcttgtt
    13081 gcttatcgtg tcactactgt gtgaattgtc gtcgctcatg gcgtcgtatg ggttctcatg
    13141 ttagttaatc aaaacgccgt cgttaatcac caacggcggg gacgtctgcc agtcaaatgc
    13201 ctggcaaatt attctttctc ggcaatgtac ggatcctcat agcccagagc aagcataatc
    13261 tctgtttcga gggcttccat ttcttctgct tcgtcatctt cgatgtgatc gtaacctaac
    13321 aaatgcagac tgccgtgcac caccatatgc gcccagtgcg cctccagtgg tttgccttgc
    13381 tcctgagctt ccttctcaac cacctgacgg cagataacca gatcgcccag tagcgacatc
    13441 tccatgccag gcggcacttc aaacgggaag gagagcacgt tggtcggctt atccttaccg
    13501 cgataggtca gattcagact gtggctttcg gcggtatcga ccacgcgaat agtcacttcc
    13561 gattcttcct gaaactgcgg gatcaccgca ttcagccatg tttgaaactg gctctcttcc
    13621 ggtaacccgg aattatcttc acatgccagt tgtaaatcga ggatcacctg actcattttt
    13681 gttcctgttc ttcgcgcttg cgttctgccg ccagcgccgc ttttcgtttt tgttcggctt
    13741 cttcccaggc ttcataggcg ttaacgatac gcgccaccac agggtgacga accacgtctt
    13801 cgctgtggaa gaagttaaag ctgatctctt cgacatcggc cagcacttcg atggcgtgac
    13861 gtaagcctga tttagtatta cgcggcaggt cgatctgtgt gacgtcgccg gtgataaccg
    13921 cttttgagtt aaaaccgata cgggtcagga acatcttcat ctgttcgatg gtggtgttct
    13981 ggctctcatc gagaatgata aacgcgtcgt tcagcgtacg accacgcata taggccagcg
    14041 gcgcgacttc aataacgttg cgctcaatca gtttctcaac tttctcaaag cccagcattt
    14101 caaacagcgc gtcgtacagc gggcgcagat acgggtctac tttctggctt aaatcgccag
    14161 gcaggaagcc cagtttctca ccggcttcga ccgccggacg agtcagcaga atacggcgaa
    14221 tctcctgacg ctccagggca tcaactgccg cagccactgc caggtaggtt ttacccgtac
    14281 ccgccgggcc aacgccgaag gtaatgtcat ggtcgagaat attggcgatg tactgcgcct
    14341 ggtttggcgt gcgcggctta attacgccgc gtttggtttt gatattgacc gctttgccgt
    14401 actccggcac gctctccgca ctttgctcca gtactcgcgc ttctttaatc gcaaggtgga
    14461 tctgttccgg ttcgatatcc tgaatctgac cgcgcatcgg ggctgtatcg acatacaggc
    14521 tacgcagaat gtctgccgca gcggtgacgc aaatcggacg gccggtcagt ttaaagtggt
    14581 tgtcgcggcg attgatctcg atgccgagac ggcgttcgag ctgcttgatg ttgtcatcaa
    14641 acgggccgca caggctcaac agacgcgcgt tgtctgctgg ctccagggtg atttcgcgag
    14701 tgtctatgtt caaaccgttc ctcttatctg tatgtcgccg gaagctgaac attcaccggc
    14761 ctataaggaa attattcacg ccacaggaaa aaggcgcaag cattgcgata aagatgggga
    14821 taaagagaga aaaaacaagg cccaccggaa cggcgggcct gagaattacg gctgataata
    14881 acccacgcca aggtcgtttt ctttgcgggt acgggcaatc accgattccg gtgtttctgc
    14941 cacgcgcaga cccatttcat cttcagtacg caccacttta ccgcgcagag agttcgggta
    15001 gacgtcggta atttctacat cgacgaattt accgatcata tccggtgtgc cctcgaagtt
    15061 gaccacgcgg ttattttcgg tacgcccgga aagctccatg atgctcttac gcgaagtccc
    15121 ttctaccaga atacgctggg tggtgccgag catccggcgg ctccacgcca tcgcttgctg
    15181 attaatgcgc tcttgcagaa tatacagacg ctgcttcttc tcttcttccg gaacatcatc
    15241 caccatatcg gcggcgggcg tccccggacg tgcagagaag ataaagctgt agctcatgtc
    15301 gaaattgacg tcggcaatca gcttcatcgt tttctcgaag tcttcggtgg tttcgccagg
    15361 gaagccaaca atgaagtcag aactgatctg aatatccgga cgcgccgcac gcagtttacg
    15421 gatgatcgct ttgtactcca gcgccgtgtg agtacggccc atcaggttca gaatgcgatc
    15481 ggaaccgctt tgtaccggca gatgcaggaa gctcaccagc tcaggcgtgt cgcggtacac
    15541 ttcgatgata tcgtcggtga attcgatcgg atggctggtg gtaaagcgaa tacgatcgat
    15601 cccgtcgatc gcagcaacca gacgcagcag atcggcaaac gatccggtgg tgccgtcgta
    15661 gttttcacca cgccaggcgt tcacgttctg accgagcagg ttgacttcac gcacgccctg
    15721 agcagcaagc tgggcaatct caaacagaat atcgtcagac ggacggctta cctcttcacc
    15781 acgggtgtaa ggcaccacgc agtaggtaca atatttattg cagccttcca tgatggagac
    15841 aaacgcggtc ggcccttcgg cgcgcggttc cggtagacgg tcaaacttct cgatttccgg
    15901 gaagctgata tctacaaccg ggctgcggtc gccgcgcacg gagttgatca tctccggcag
    15961 acggtgcagc gtttgcggcc caaaaataat atcgacatag tgggcgcgct ggcgaatgtg
    16021 ctcgccttct tgcgatgcca cgcagccacc gacgccgata atcaggtctg gattcttctc
    16081 ttttaacagt ttccagcgac ccaactgatg gaagactttt tcctgagcct tctcgcggat
    16141 tgagcaggtg ttcagcagca gcacatccgc ttcttccgcc acgtcggtca gttgatagcc
    16201 gtgggtggca tccagcagat cggccatctt cgatgaatcg tactcgttca tctgacagcc
    16261 ccaggtttta atatggagtt ttttggtcat cgacttgctc ttgcgaaata gtagccagga
    16321 atgcagggcg catagtgtaa tgctttgctg ccgttgtgac cagtatgagc gttatcagcc
    16381 cttgggggta aaaatcctgt aaacttaaag catattgcta acaggatgat tgaccatgac
    16441 aaatcaacca acggaaattg ccattgtcgg cggaggaatg gtcggcggcg cactggcgct
    16501 ggggctggca cagcacggat tttcggtaac ggtgatcgag cacgcagaac ctgcaccgtt
    16561 tgtcgctgat agccaaccgg acgtgcggat ctcggcgatc agcgccgcat cggtatcatt
    16621 gcttaaaggg ttaggggtct gggatgcagt acaggctatg cgttgccatc cttaccgcag
    16681 actggaaacg tgggagtggg aaacggcgca tgtgatgttt gacgccgctg aacttaagct
    16741 gccgctgctt ggctatatgg tggaaaacac cgtcctgcaa caggcattgt ggcaggcgct
    16801 ggaagctcat ccgaaagtaa cgttacgtgt gccaggctcg ctgattgcat tacatcgaga
    16861 taatgatctt caggagctgg aactgaaggg cggtgaagtg attcgcgcga agctggtgat
    16921 tggtgctgac ggcgcaaatt cgcaggtgcg gcagatggcg ggaattggcg ttcatgcctg
    16981 gcagtatgcg cagtcgtgta tgttgattag cgtacagtgt gagaacgatc ccggcgacag
    17041 cacctggcag caatttaccc cggacggacc gcgtgcgttt ctgccgttgt ttgataactg
    17101 ggcatcgctg gtgtggtatg actctccggt acgtattcgc cagttgcaga atatgaatat
    17161 ggcgcaactc caggcggaaa tcgcgaagca tttcccgtcg cgtctgggtt acgttacacc
    17221 gcttgccgct ggtgcgtttc cgctgacgcg ccgacatgcg ttgcagtatg tgcagccggg
    17281 gcttgcgctg gtgggcgatg ccgcgcatac catccatccg ctggcggggc agggggtgaa
    17341 tcttggttat cgtgatgtcg atgccctgat tgatgttctg gtgaatgccc gcagctacgg
    17401 tgaagcgtgg gccagttatc ctgtcctcaa gcgttaccag atgcggcgca tggcggataa
    17461 cttcattatg caaagtggta tggatctgtt ttatgccgga ttcagtaata atctgccgcc
    17521 gctgcgtttt gtgcgtaatc tcgggttaat ggcggcagag cgtgctggcg tgttgaaacg
    17581 tcaggcgctg aaatatgcgt tagggttgta gccttacaac attgccggat gcgtgccaac
    17641 cgtaggtcgg ataagacgcg gcagcgtcgc atccgacatt gaaggataag acgtgtcaac
    17701 atcgcattcg acattgaatg aacgcagaaa agcaaaaagc tcgccgaagc gagctttttt
    17761 aatgtggctg gggtacgagg attcgaacct cggaatgccg gaatcagaat ccggtgcctt
    17821 accgcttggc gataccccaa caaattggtt tttgaatttg ccgaacgtat tcgacacatt
    17881 cagaatttgg tggctacgac gggattcgaa cctgtgaccc catcattatg agtgatgtgc
    17941 tctaaccaac tgagctacgt agccagattg t
//
LOCUS       DAPGUL010000089        17930 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.090, whole genome shotgun sequence.
ACCESSION   DAPGUL010000089 DAPGUL010000000
VERSION     DAPGUL010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17930
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.090"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            89..607
                     /locus_tag="RHX21_003277"
     CDS             89..607
                     /locus_tag="RHX21_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfiR family protein"
                     /protein_id="HDV1988425.1"
                     /translation="MRFSHRLFLLLILLLTGAPILAQEPSDVAKNVRMMVSGIVSYTR
                     WPALSGPPKLCIFSSSRFSTALQENAATSLPYLPVIIHTQQEAMISGCNGFYFGNESP
                     TFQMELTEQYPSKALLLIAEQNTECIIGSAFCLIIHNNDVRFAVNLDALSRSGVKVNP
                     DVLMLARKKNDG"
     gene            597..1823
                     /gene="dgcN"
                     /locus_tag="RHX21_003278"
     CDS             597..1823
                     /gene="dgcN"
                     /locus_tag="RHX21_003278"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcN"
                     /protein_id="HDV1988426.1"
                     /translation="MMDNDNSLNKRPTFKRALRNISMTSIFITMMLIWLLLSVTSVLT
                     LKQYAQKNLALTAATMTYSLEAAVVFADGPAATETLAALGQQGQFSTAEVRDKQQNIL
                     ASWHYTRKDPGDTFSNFISHWLFPAPIIQPIRHNGETIGEVRLTARDSSISHFIWFSL
                     AVLTGCILLASGIAITLTRHLHNGLVEALKNITDVVHDVRSNRNFSRRVSEERIAEFH
                     RFALDFNSLLDEMEEWQLRLQAKNAQLLRTALHDPLTGLANRAAFRSGINTLMNNSDA
                     RKTSALLFLDGDNFKYINDTWGHATGDRVLIEIAKRLAEFGGLRHKAYRLGGDEFAMV
                     LYDVQSESEVQQICSALTQIFNLPFDLHNGHQTTMTLSIGYAMTIEHASAEKLQELAD
                     HNMYQAKHQRAEKLVR"
     gene            1839..2321
                     /locus_tag="RHX21_003279"
     CDS             1839..2321
                     /locus_tag="RHX21_003279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HDV1988427.1"
                     /translation="MIKHLVAPLIFTSLILTGCQSPQGKFTPEQVAAMQSYGFTESAG
                     DWSLGLSDAILFAKNDYKLLPESQQQIQTMAAKLASTGLTHARMDGHTDNYGEDSYNE
                     GLSLKRANVVADAWAMGGQIPRSNLTTQGLGKKYPIASNKTAQGRAENRRVAVVITTP
                     "
     gene            complement(2398..2745)
                     /gene="rplS"
                     /locus_tag="RHX21_003280"
     CDS             complement(2398..2745)
                     /gene="rplS"
                     /locus_tag="RHX21_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012768745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HDV1988428.1"
                     /translation="MSNIIKQLEQEQMKQDVPSFRPGDTVEVKVWVVEGSKKRLQAFE
                     GVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSISVKRRGAVRKAKLYYLRE
                     RTGKAARIKERLN"
     gene            complement(2787..3554)
                     /gene="trmD"
                     /locus_tag="RHX21_003281"
     CDS             complement(2787..3554)
                     /gene="trmD"
                     /locus_tag="RHX21_003281"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HDV1988429.1"
                     /translation="MWIGIISLFPEMFRAITDYGVTGRAVKNGLLSIQSWSPRDFTHD
                     RHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSEL
                     ATNQKLILVCGRYEGIDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVSRFIPGVL
                     GHEASATEDSFAEGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWL
                     RRPELLENLALTEEQARLLAEFKTEHAQQQHKHDGMA"
     gene            complement(3585..4133)
                     /gene="rimM"
                     /locus_tag="RHX21_003282"
     CDS             complement(3585..4133)
                     /gene="rimM"
                     /locus_tag="RHX21_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HDV1988430.1"
                     /translation="MSKQLTAQAPVDPIVLGKMGSSYGIRGWLRVFSSTEDAESIFDY
                     QPWFIQKAGQWQQVQLESWKHHNQDMIIKLKGVDDRDAANLLTNCEIVVDSSQLPQLE
                     EGDYYWKDLMGCQVVTTEGYDLGKVVDMMETGSNDVLVIKANLKDAFGIKERLVPFLD
                     GQVIKKVDLTTRSIEVDWDPGF"
     gene            complement(4152..4400)
                     /gene="rpsP"
                     /locus_tag="RHX21_003283"
     CDS             complement(4152..4400)
                     /gene="rpsP"
                     /locus_tag="RHX21_003283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HDV1988431.1"
                     /translation="MVTIRLARHGAKKRPFYQVVVADSRNARNGRFIERVGFFNPIAS
                     EKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVNKAA"
     gene            complement(4537..5898)
                     /gene="ffh"
                     /locus_tag="RHX21_003284"
     CDS             complement(4537..5898)
                     /gene="ffh"
                     /locus_tag="RHX21_003284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HDV1988432.1"
                     /translation="MFDNLTDRLSRTLRNISGRGRLTEDNVKDTLREVRMALLEADVA
                     LPVVREFINRVKEKAVGHEVNKSLTPGQEFVKIVRNELVAAMGEENQTLNLAAQPPAV
                     VLMAGLQGAGKTTSVGKLGKFLREKHKKKVLVVSADVYRPAAIKQLETLAEQVGVDFF
                     PSDVGQKPVDIVNAALKEAKLKFYDVLLVDTAGRLHVDEAMMDEIKQVHASINPVETL
                     FVVDAMTGQDAANTAKAFNEALPLTGVVLTKVDGDARGGAALSIRHITGKPIKFLGVG
                     EKTEALEPFHPDRIASRILGMGDVLSLIEDIESKVDRAQAEKLASKLKKGDGFDLNDF
                     LEQLRQMKNMGGMASLMGKLPGMGQIPDNVKSQMDDKVLVRMEAIINSMTMKERAKPE
                     IIKGSRKRRIAAGCGMQVQDVNRLLKQFDDMQRMMKKMKKGGMAKMMRSMKGMMPPGF
                     PGR"
     gene            6065..6856
                     /locus_tag="RHX21_003285"
     CDS             6065..6856
                     /locus_tag="RHX21_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417102.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YpjD"
                     /protein_id="HDV1988433.1"
                     /translation="MPVFALLALVAYSVSLALIVPGLLQKNGGWRRMAIISAVIALVC
                     HAIALEARILPDGDSGQNLSLLNVGSLVSLMICTVMTIVASRNRGWLLLPIVYAFALI
                     NLALATFMPNEYITHLEATPGMLVHIGLSLFSYATLIIAALYALQLAWIDYQLKNKTL
                     AFNQEMPPLMSIERKMFHITQIGVVLLTLTLCTGLFYMHNLFSMENIDKAVLSIVAWF
                     VYIVLLWGHYHEGWRGRRVVWFNVAGAVILTLAYFGSRIVQQLIS"
     gene            6877..8163
                     /locus_tag="RHX21_003286"
     CDS             6877..8163
                     /locus_tag="RHX21_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026171.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDV1988434.1"
                     /translation="MEHISTTTLIIILIIMVVISAYFSGSETGMMTLNRYRLRHMAKQ
                     GNRSAKRVEKLLRKPDRLISLVLIGNNLVNILASALGTIVGMRLYGDAGVAIATGVLT
                     FVVLVFAEVLPKTIAALYPEKVAYPSSFLLAPLQILMMPLVWLLNAITRMLMRMMGIK
                     TDIVVSGSLSKEELRTIVHESRSQISRRNQDMLLSVLDLEKMTVDDIMVPRSEIIGID
                     INDDWKSILRQLSHSPHGRIVLYRDSLDDAISMLRVREAWRLMSEKKEFTKETMLRAA
                     DEIYFVPEGTPLSTQLVKFQRNKKKVGLVVNEYGDIQGLVTVEDILEEIVGDFTTSMS
                     PTLAEEVTPQNDGSVIIDGTANVREINKAFNWHLPEDDARTVNGVILEALEEIPVAGT
                     RVRIGEYDIDILDVQDNMIKQVKVFPVKPLRESVAE"
     gene            complement(8218..8811)
                     /gene="grpE"
                     /locus_tag="RHX21_003287"
     CDS             complement(8218..8811)
                     /gene="grpE"
                     /locus_tag="RHX21_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HDV1988435.1"
                     /translation="MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKI
                     ANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDIEKAHKFALEKFINELLPVIDSL
                     DRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMV
                     ESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAKA"
     gene            8934..9812
                     /gene="nadK"
                     /locus_tag="RHX21_003288"
     CDS             8934..9812
                     /gene="nadK"
                     /locus_tag="RHX21_003288"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) kinase"
                     /protein_id="HDV1988436.1"
                     /translation="MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCTKGYEVIVEQQIA
                     HELQLKNVKTGTLAEIGQLADLAVVVGGDGNMLGAARTLARYDIKVIGINRGNLGFLT
                     DLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMI
                     EFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSA
                     RPLVINSSSTIRLRFSHRRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYS
                     YFNTLSTKLGWSKKLF"
     gene            9898..11559
                     /gene="recN"
                     /locus_tag="RHX21_003289"
     CDS             9898..11559
                     /gene="recN"
                     /locus_tag="RHX21_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HDV1988437.1"
                     /translation="MLAQLTISNFAIVRELEIDFHSGMTVITGETGAGKSIAIDALGL
                     CLGGRAEADMVRTGAARADLCARFSLKDTPAALRWLEENQLEDGHECLLRRVISSDGR
                     SRGFINGTAVPLSQLRELGQLLIQIHGQHAHQLLTKPEHQKFLLDGYANETSLLQEMT
                     ARYQLWHQSCRDLAHHQQLSQERAARAELLQYQLKELNEFNPQPGEFEQIDEEYKRLA
                     NSGQLLTTSQNALALMADGEDANLQSQLYTAKQLVSELIGMDSKLSGVLDMLEEATIQ
                     IAEASDELRHYCDRLDLDPNRLFELEQRISKQISLARKHHVSPEALPQYYQSLLEEQQ
                     QLDDQADSQETLALAVTKHHQQALEIARALHQQRQQYAEELAQLITDSMHALSMPHGQ
                     FTIDVKFDEHHLGADGADRIEFRVTTNPGQPMQPIAKVASGGELSRIALAIQVITARK
                     METPALIFDEVDVGISGPTAAVVGKLLRQLGESTQVMCVTHLPQVAGCGHQHYFVSKE
                     TDGAMTETHMQSLNKKARLQELARLLGGSEVTRNTLANAKELLAA"
     gene            11708..12049
                     /gene="bamE"
                     /locus_tag="RHX21_003290"
     CDS             11708..12049
                     /gene="bamE"
                     /locus_tag="RHX21_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417107.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamE"
                     /protein_id="HDV1988438.1"
                     /translation="MRCKTLTAAAAVLLMLTAGCSTLERVVYRPDINQGNYLTANDVS
                     KIRVGMTQQQVAYALGTPLMSDPFGTNTWFYVFRQQPGHEGVTQQTLTLTFNSSGVLT
                     NIDNKPALSGN"
     gene            complement(12111..12401)
                     /locus_tag="RHX21_003291"
     CDS             complement(12111..12401)
                     /locus_tag="RHX21_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417108.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfH family protein"
                     /protein_id="HDV1988439.1"
                     /translation="MPGKIAVEVAYALPEKQYLQRVTLQEGATVEEAIRASGLLELRT
                     DIDLTKNKVGIYSRPAKLSDSVHDGDRVEIYRPLIADPKELRRQRAEKSANK"
     gene            complement(12391..12828)
                     /gene="ratA"
                     /locus_tag="RHX21_003292"
     CDS             complement(12391..12828)
                     /gene="ratA"
                     /locus_tag="RHX21_003292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010376629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin RatA"
                     /protein_id="HDV1988440.1"
                     /translation="MPQISRTALVPYSAEQMYQLVNDVQSYPQFLPGCTGSRILESTP
                     GQMTAAVDVSKAGISKTFTTRNQLTSNQSILMNLVDGPFKKLIGGWKFTPLSQEACRI
                     EFHLDFEFTNKLIELAFGRVFKELASNMVQAFTVRAKEVYSAR"
     gene            12999..13481
                     /gene="smpB"
                     /locus_tag="RHX21_003293"
     CDS             12999..13481
                     /gene="smpB"
                     /locus_tag="RHX21_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HDV1988441.1"
                     /translation="MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGREVKSL
                     RAGKANISDSYVLLRDGEAFLFGANITPMAVASTHVVCDPTRTRKLLLNQRELDSLYG
                     RVNREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDIKEREWQVDKARIMKNAHR
                     "
     gene            13696..14058
                     /gene="ssrA"
                     /locus_tag="RHX21_003294"
     tmRNA           13696..14058
                     /gene="ssrA"
                     /locus_tag="RHX21_003294"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            14264..15505
                     /locus_tag="RHX21_003295"
     CDS             14264..15505
                     /locus_tag="RHX21_003295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HDV1988442.1"
                     /translation="MARQTKPLSVKEIESAKPKEADYVLYDGDGLELLIKSSGSKIWQ
                     FRYIRPVTKKRAKKSIGSYPSVTLADARNYRAESRSLLAKQIDPQEHQQEQLRSSLEA
                     KTNTFQLVAERWWNVKKASVTEDYAEDIWRSLERDVFPAIGDVSVTDIKAHTLVQAVQ
                     PVQARGALETVRRLCQRINEVMIYAQNTGLIDAVPSVNIGKAFEKPQKKNMPSIRPDQ
                     LPQLMQTMRTASISLSTRCLFMWQLLTITRPAEAAEALWEEVDIEAREWKIPAARMKM
                     NRDHTVPLSDEAIAILEMMKPLSGNREFIFPSRIKPNQPMNSQTVNASLKRAGFGGVL
                     VSHGLRSIASTALNEQGFPPDVIEAALAHVDKNEVRRAYNRSDYLEQRRPMMQWWADF
                     VMAADHGSMIEGGIKAMRLVG"
     gene            complement(15644..17896)
                     /locus_tag="RHX21_003296"
     CDS             complement(15644..17896)
                     /locus_tag="RHX21_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988443.1"
                     /translation="MTPQDFVNKIVQSIPGLANDHRLFVSLRDQLPLLAEAAPGPFLD
                     ALEQLLKGNGEMIAPIFNEDKGLLTPRSHYHGLKWALEALAWEQTYLLRAAICLAKLA
                     VIDPGGTYSDRPLNSLRTIFLAWSPNTWAPVKVRNAIIKKIITIVPSIGWSLLQNLLP
                     RSHDTSDQNQKMKFRESDKDVEKLTWGVVWEGQIFIIQEAIKLAGILPTRWEILISHL
                     SSFPENAIDETLSHLELCLSQQTEEDQFIVWEALRHEYSRHKKYSDANWAFKFESIEK
                     IAKILDNYKPIDMVRASLWIFNDWDSDIEESIENAGGIFSSVEEMRSEKLREIYFTLG
                     LSGVKDLFQQVNNVFIAARHISALSLDEEKLNDLFVMLINNKKNIDEVCGLLMQYGVE
                     CFGAEWLNKIKVYFKQFKITPDRAGKILASLRDSQEIWSIIEGFEDNINEKYWLQKQP
                     IAMMGKTSDLFVLMDKYIERGRGLAAIISANQRLSEIPSTTLLYLLDIVVKEINSQDI
                     QFDTMLSYYVKKVFDELKQRNDVSETDLAFKEMTYLPCFPDSDEPLILHRLMMKKPEV
                     FIEAICIVYRSDEDEQTEPSELEVKRATSIYRLLEKLRILPGQIDNEIDQDKLEDWCE
                     NVRHLAKLHHRQEITDHVIGKILAHAPNSSVDNSWPHEAIRHIIEILSSDELEQGIQI
                     GRYNKRGVFARMRYEGGNQERILAEQYREWANSMPHCVRTSAMLFRIADEWEYSAKNA
                     DIRAAKADLK"
BASE COUNT         4636 a         4574 c         4095 g         4625 t
ORIGIN      
        1 gatgacggtc gcatgaaaaa atgatatttt aatgagcatt ctgaaaaaat atcgatgcat
       61 ttcgagcgaa gatggtgggg atccctgaat gcgtttttct caccgactgt tcttacttct
      121 gattctcctg ctgacgggag caccaatact cgctcaggag ccttctgacg ttgcgaaaaa
      181 cgtgcgtatg atggtttccg gtattgtcag ttacacccgc tggcctgcgc tatcagggcc
      241 accaaagtta tgtatctttt catcttcacg ttttagtacc gccctacaag agaatgccgc
      301 gacatctttg ccttatctgc ctgtcatcat tcacactcaa caagaggcga tgatttcagg
      361 ctgcaatggt ttttattttg gcaacgagtc accgacattc cagatggaat taaccgaaca
      421 atatccgtca aaggcgttat tattaattgc cgaacaaaat accgagtgca ttattggtag
      481 cgccttttgt ctgatcatcc acaataatga cgtcagattt gccgtaaacc tggatgcctt
      541 atcgcgtagc ggtgtaaagg tcaacccgga tgtcttaatg ctcgcacgga agaaaaatga
      601 tggataacga taattctctt aataagcgcc ccacgtttaa aagagcatta cgcaacatca
      661 gtatgaccag catatttatc actatgatgc tgatctggtt gctgctttcc gtgacctcgg
      721 tgctgaccct gaaacagtac gcgcaaaaaa acctggcact gacagcagca acaatgactt
      781 acagtctgga agcagctgtc gtttttgccg atggccctgc agcaactgaa acactggcag
      841 cgctgggcca acaagggcaa ttttcaactg cagaagtacg tgataagcag caaaatattc
      901 tggcatcctg gcattacacc cgtaaggatc caggcgatac tttcagcaat ttcataagcc
      961 actggctctt ccctgccccc atcattcagc cgattcgtca caatggtgaa accattggcg
     1021 aagtacgctt aaccgctcgc gacagttcaa tcagccattt tatctggttt tcgctcgccg
     1081 tactgaccgg ttgtattctg ctggcatcag gcatcgcaat taccctcacc cgccatttgc
     1141 acaatggcct ggtggaagca ctgaaaaata tcaccgatgt cgtacatgat gtgcgttcca
     1201 accgcaattt ttcccgacga gtttcggaag aacgtattgc tgagtttcac cgcttcgctc
     1261 tcgacttcaa cagtctgctg gatgaaatgg aagagtggca gcttcgttta caggccaaaa
     1321 atgcgcagct tctgcgtacc gcactacatg acccattaac cgggctggct aaccgcgcag
     1381 cgtttcgtag cggcatcaat acgttgatga acaattccga tgcccgaaaa acgtcggcgt
     1441 tactatttct tgatggcgat aatttcaaat atatcaatga tacctggggt catgcgacgg
     1501 gcgatagagt cttgattgaa atcgcaaaac ggttagctga atttggcggg ctgcgacata
     1561 aagcataccg cctgggcggc gatgaattcg ctatggtgct ctatgatgta cagtcggaat
     1621 ctgaagtgca gcagatatgc tcagcactga cacaaatctt taatctcccg tttgatcttc
     1681 ataatggcca tcagaccacc atgacattaa gcattggtta cgcgatgacc attgagcacg
     1741 cctctgcgga aaaattacaa gagcttgccg atcacaatat gtatcaggcc aaacaccagc
     1801 gtgccgaaaa gctggtgaga taacaaggat atatcgatat gataaagcac ctggtagcac
     1861 ccctgatttt cacctcacta atactgactg gctgccagtc ccctcaggga aagtttactc
     1921 ctgagcaagt cgccgctatg caatcttatg gatttactga atccgccggc gactggtcgc
     1981 tgggcttatc agatgccatt ctgttcgcaa aaaatgacta caaattgctc ccggaaagcc
     2041 agcaacagat ccaaaccatg gcagccaaat tggcctcgac agggctaaca catgcccgta
     2101 tggatggaca caccgataac tatggtgaag acagttacaa cgaaggctta tcattgaaac
     2161 gggcgaatgt cgtggccgat gcatgggcta tgggtggaca aattccacgc agcaatctca
     2221 ccacacaggg tttaggaaaa aaatatccca tagccagtaa caagaccgcc cagggccgcg
     2281 ccgagaaccg ccgcgtcgca gtggtgatta caacccctta aaacacgagc aaacagacaa
     2341 aaaaagggcc agccaattgg ccagcccttc ttaacaggat gtcgcttaag cgaaatctta
     2401 gttaagacgc tctttgatac gagcagcctt accagtacgc tcacgcaggt agtacagttt
     2461 agctttacga acagcaccac gacgtttgac agaaatgctg tcaactaccg gagagtgagt
     2521 ctggaagaca cgctcaacgc cttcgccgtt ggaaatttta cgaacagtga atgcagagtg
     2581 cagaccgcgg ttacgaatag cgataaccac gccctcgaat gcctgcagac gttttttgga
     2641 accttcaaca acccatactt tcacttccac ggtatcaccc ggacggaagg aaggtacgtc
     2701 ctgcttcatc tgctcttgtt caagttgctt aataatgttg ctcataattt aatctcttat
     2761 cctgggtaaa ctgatatctc gggggcttac gccatcccat catgtttatg ttgctgttgt
     2821 gcgtgttccg ttttgaactc cgccagcaac cttgcttgct cttcagtcag agccaggttt
     2881 tccagaagtt caggtcttct aagccaggta cggcccagcg actgtttcaa acgccagcga
     2941 cgtatctcgg catggttgcc cgacagtaac actggcggaa cttccatccc ttctaacacc
     3001 tcaggccgcg tatagtgcgg gcaatccagc aatccttcag caaaggaatc ttccgttgcc
     3061 gaggcttcat gtcccagtac tcccggaata aaccgggaaa cggagtcaat cagcgtcatt
     3121 gctggtaact caccaccact gagaacgtaa tcgccgattg accattcttc gtcaatttcg
     3181 gtttggatca cgcgctcatc tataccttcg tagcgaccgc acaccagaat caatttttga
     3241 ttcgttgcca gttcgctgac gcccgcttga tcaagcttgc gtccctgtgg tgacagataa
     3301 atcacctttg cgccttcacc cgccgcggct tttgctgcat gaatggcgtc ccgcaagggt
     3361 tgcaccatca ttaacatccc cggtccgccg ccgtaaggac gatcgtccac ggtacggtgc
     3421 cggtcatgcg tgaagtcgcg aggactccaa ctctggatgc tcagcaggcc atttttaact
     3481 gcccggccag ttaccccgta atcggtaatt gcgcggaaca tttcaggaaa caggctaatt
     3541 atgccaatcc acatagcgcc gtcttttacc gtttatccgg tggtttaaaa accaggatcc
     3601 caatctactt cgattgaacg agtagtgaga tcgactttct tgataacctg cccatcgagg
     3661 aacggtacga gacgttcctt gataccaaac gcatctttca ggtttgcctt aatgacgaga
     3721 acgtcattag atccggtttc catcatatcg acgactttac cgagatcgta gccttcagtg
     3781 gttactacct ggcagcccat caggtctttc cagtagtagt caccctcttc aagctgaggc
     3841 agctgcgatg aatccacgac aatttcacaa ttcgtcagca ggttcgccgc atcacgatcg
     3901 tcaacgcctt tcagcttgat gatcatgtcc tgattgtggt gcttccagct ttccagctgg
     3961 acttgctgcc actgacccgc cttctggata aaccagggct gatagtcaaa aatgctttcg
     4021 gcgtcttcgg tggaagaaaa cactctgagc cacccacgaa taccgtaaga cgaacccatt
     4081 ttccccaaaa cgatgggatc aacaggtgct tgcgcggtga gttgtttgct catcatgacc
     4141 accgtgacag attaagctgc tttgtttact tctttgatca gcgcagcaac gcgatcagaa
     4201 atagttgcgc cctggccaac ccagtgagcg atgcgatcca gatccaggcg agtgccttct
     4261 tctttttcgc tagcgattgg gttgaagaaa ccaacgcgct cgatgaagcg accgttgcgt
     4321 gcattacggc tgtcagcgac aacaacctgg tagaacggac gctttttagc gccgtgacgt
     4381 gctaaacgaa tagttaccat aacatcctct tgtgtgaata aaacaaccgg accccatcga
     4441 ggaacggagt ccggtgtcat attaaaagcc cgaaaatttt actgatttct ggagaaaatg
     4501 caatcagcag ttaataactc tgtcgcataa ggtcatttag cgaccaggaa atcccggcgg
     4561 catcatcccc ttcatgcttc tcatcatctt cgccattccg cctttcttca ttttcttcat
     4621 catgcgctgc atgtcgtcga actgcttcag aaggcggttc acgtcctgca cctgcatacc
     4681 gcaaccggca gcgatacgac gcttacgcga acctttgatg atttctggct tagcgcgctc
     4741 tttcatcgtc atcgagttga tgatggcttc catacgcacc agcactttat cgtccatctg
     4801 cgacttaaca ttatccggga tctgccccat gcccggcagc ttgcccatca ggctagccat
     4861 gccgcccata tttttcatct ggcgcagttg ctcaagaaaa tcgttgagat cgaagccgtc
     4921 gccttttttc agcttgctgg ctaatttctc tgcctgcgcg cggtcaactt tgctttcgat
     4981 atcttcgatc agcgacagta cgtcgcccat gccgagaata cgcgacgcga tgcggtccgg
     5041 atggaacggc tccagcgcct cagttttctc gccaacaccg agaaacttga tcggtttgcc
     5101 agtgatgtga cgaatagaga gcgccgcacc gccgcgggca tcgccgtcca ctttggtcaa
     5161 cactacgccg gtaagcggta acgcttcatt gaatgctttt gccgtattgg ccgcatcctg
     5221 accggtcatg gcgtcaacca caaacagggt ttcaaccggg ttaatcgacg catggacttg
     5281 tttgatctcg tccatcatcg cttcgtcaac gtgcagacga ccagcggtat ccaccagcag
     5341 cacgtcgtag aatttcagtt tggcttcttt cagcgccgcg ttaacgatat ctaccggctt
     5401 ctgaccaaca tcagaaggga agaaatcaac gcccacctgc tctgccagcg tctcaagctg
     5461 tttgattgcc gccgggcgat aaacgtcggc agaaaccacc agcactttct tcttgtgctt
     5521 ctcgcgcagg aacttaccga gtttaccaac gctggttgtt ttaccggcac cttgcaggcc
     5581 cgccatcagc acgaccgcag gcggttgcgc cgccaggttc agggtctggt tctcttcgcc
     5641 catcgccgca accagttcgt tacggacgat tttgacgaac tcctgccccg gcgtcaggct
     5701 cttattaact tcatgaccaa ccgctttctc ttttacgcga ttgataaact cacgcactac
     5761 cggcagagcg acatccgcct ccagcagcgc catgcgcact tcgcgcagcg tatcttttac
     5821 gttgtcttca gtgaggcgtc cacggccact gatattgcgc agcgtgcgcg acaaacgatc
     5881 ggttaaatta tcaaacattg tctctcgcct ggggtggaaa cggttggccg caatcgcgac
     5941 acatcatcag tattttgccg cagtataaca tgaaggcgtc tttgttgtta tgcaacggtt
     6001 ggagcagcgt tcacctgacg ctatactgct tctctttctt attgctcaaa ctgtcgacat
     6061 cactatgccc gtttttgctc tgctcgcgct tgtcgcctac tccgtcagtc ttgcgctgat
     6121 tgttcccggt ctgctgcaaa aaaacggcgg ctggcggcgc atggctatta tttctgcggt
     6181 cattgcgctg gtctgccacg caatcgctct ggaagcccgc atcctgcccg acggtgatag
     6241 cggacaaaac ctcagcctgc tgaacgttgg ttcattggtc agtttgatga tctgtacggt
     6301 aatgaccatt gtggcttctc gcaatcgtgg ctggttgctg ctacccattg tctatgcctt
     6361 tgcgcttatc aacctggcgc tggcgacctt catgcccaat gaatacatca cccatctgga
     6421 agcaacgcca gggatgctgg tgcacattgg cttatcgctc ttttcctatg ccacgctaat
     6481 tatcgccgcc ctgtacgcgc tgcaactggc gtggattgat taccaactga agaacaagac
     6541 gctggcattt aaccaggaaa tgccgccatt gatgagtatc gagcgtaaaa tgttccacat
     6601 cacgcagatt ggcgtggtgc tgctaacgct cacgctttgc actggcctgt tctacatgca
     6661 caacttattt agcatggaaa atatcgacaa ggccgtgctc tctatcgtgg cgtggtttgt
     6721 ctatattgtg ctgctgtggg gacattatca tgaaggatgg cgtggacgcc gcgtcgtctg
     6781 gtttaacgtt gcgggtgcag tcatcctgac actggcctac ttcggcagcc gaattgtcca
     6841 gcagttaatc agctaaaccc agaaaaggag tttcccctgg aacacatttc tactactacg
     6901 ttgatcatta ttctgatcat catggtggtc atttcagcct atttttccgg gtccgaaacc
     6961 ggaatgatga ccctcaaccg ctatcgtctg cgacatatgg cgaaacaggg taatcgctcg
     7021 gccaaacgcg tcgaaaaatt gctgcgtaag ccagaccgcc tgataagcct ggtgttaatc
     7081 ggcaataacc tggtcaatat tcttgcctcc gcgctcggca ctattgttgg gatgcgtttg
     7141 tacggcgatg cgggcgtggc aattgcgact ggtgtgctga cttttgtcgt actggttttt
     7201 gctgaggtat tgccgaaaac cattgccgcg ctgtacccgg aaaaagtcgc ttatccgagt
     7261 agttttctgc tggctccgct gcaaattttg atgatgccgc tggtctggtt gctgaatgct
     7321 atcacccgta tgctgatgcg catgatgggt atcaaaaccg atatcgtggt tagcggctct
     7381 ttgagcaaag aagagttgcg cactatcgtg cacgaatcac gctcacaaat ttcccgtcgc
     7441 aatcaggata tgctactgtc tgtgctcgat ctggaaaaga tgaccgttga tgacatcatg
     7501 gtgccgcgca gtgaaattat cggtattgat atcaacgatg actggaaatc gattctgcgc
     7561 caactctccc actcacctca cgggcgcatc gtgctctacc gtgattcgct ggacgacgcc
     7621 atcagtatgc tgcgagtacg tgaagcctgg cggttgatgt cggagaaaaa agagttcacc
     7681 aaagaaacca tgctgcgcgc cgcggacgag atctattttg tgccggaagg tacgccgctc
     7741 agcacgcagt tggtaaagtt tcagcgcaac aaaaagaaag tcggcctggt cgtcaacgag
     7801 tatggcgaca ttcaggggct ggtgacggtt gaagatattc tggaagagat tgtcggcgat
     7861 ttcactacgt cgatgtcgcc aacacttgcc gaagaggtca cgccgcaaaa cgacggttcg
     7921 gtgattatcg atggcaccgc caacgtgcgg gaaatcaaca aagcctttaa ctggcatcta
     7981 ccggaagatg atgcccgcac ggttaatggc gtcattcttg aggcactgga agagatccct
     8041 gtcgcaggca cccgcgtgcg tattggcgag tacgatatag atattctcga cgtacaggac
     8101 aatatgatta agcaggtaaa agtttttcct gtgaaaccgc tgcgcgagag tgtggcggag
     8161 taacgaaaac ggccctgcat tcgcatgcag ggccgttaat tattacgaaa acagaaatta
     8221 cgcttttgct ttcgctacag ttaccatcgc cgcacgaatc gtacgaccat tcagcgtata
     8281 acccttctgc ataatgccca gtacgttacc tggcgcaacg tcatcagatt ccaccattgc
     8341 gatagcctga tgcacattcg ggtccagcgg cacgttagtt tcggcgatca cttcaacacc
     8401 aaacttacgc acaacatcca gcatcgactt cagcgtcagc tcaatgcctt caaccatcgc
     8461 agacatatcc gggttagctt tatcagccac ttccagcgca cgatccaggc tatcaatcac
     8521 cggcagcaat tcgttgatga atttctccag cgcgaatttg tgggcttttt caatatccag
     8581 ttcagtacgt cgacgcaggt tttccatttc ggcttttaca cgcaaaatgc cgtcacgttc
     8641 acgggtctgg gcttcagcca gctgagcttc gagattcgca attttttcat cgcgcggatc
     8701 cacctgctca gcagaagctt ctggctcaac tgcctcaatc tcttcgtgct gatccatgat
     8761 aatttcttcc ggggcttgcc cctcaggcgt tttctgttct ttactactca tgaatttctc
     8821 cgcgtttttt tcgcattcat ctcgctaact tcgcttatta tggggatcag tttcagggtt
     8881 tcaagggaag cactcacatt gtcatcaatc ttcgcaacaa ggacctcgga aaaatgaata
     8941 atcatttcaa gtgtattggc attgtgggac acccacggca ccccactgca ctgacaacac
     9001 atgaaatgct ctaccgctgg ctgtgcacaa aaggttacga ggtcatcgtt gagcaacaaa
     9061 tcgctcacga actgcaactg aagaatgtga aaactggcac gctcgcggag attgggcaac
     9121 tagctgatct cgcggtagtc gttggtggcg acggtaatat gctgggcgcg gcacgcacac
     9181 tcgcccgtta cgatattaaa gttattggaa tcaaccgtgg caacctgggt ttcctgactg
     9241 accttgaccc cgataacgcc cagcaacagt tagccgatgt gctggaaggc cactacatca
     9301 gcgagaaacg ttttttgctg gaagcgcaag tctgtcagca agattgccaa aagcgcatca
     9361 gcaccgcgat aaatgaagtg gtgcttcatc caggcaaagt ggcgcatatg atagagttcg
     9421 aagtgtatat cgacgagatc tttgcgtttt ctcagcgatc tgatggacta attatttcga
     9481 cgccaacagg ctccaccgcc tattccctct ctgcaggcgg tcctattctg accccctctc
     9541 tggatgcgat taccctggtg cccatgttcc cgcatacgtt gtcagcacga ccactggtca
     9601 taaacagcag cagcacgatc cgtctgcgtt tttcgcatcg ccgtaacgac ctggaaatca
     9661 gttgcgacag ccagatagca ctgccgattc aggaaggtga agatgtcctg attcgtcgct
     9721 gtgattacca tctgaatctg attcatccga aagattacag ttatttcaac acattaagca
     9781 ccaagctcgg ctggtcaaaa aaattattct aattttacgc cagcctcttt actgtatata
     9841 aaaccagttt atactgtaca caataacagt aatggttttt catacaggaa aacgactatg
     9901 ttggcacaac tgaccatcag caactttgct atcgttcgtg agcttgagat tgattttcat
     9961 agcggcatga ccgtaataac tggcgagacc ggcgcgggta aatctattgc aatagatgcc
    10021 ctcggtcttt gtctcggtgg tcgcgctgaa gccgacatgg tgcgtaccgg cgctgctcgc
    10081 gctgacctgt gcgcccgttt ttctctgaaa gatacgccag cggctctgcg ctggctggaa
    10141 gaaaatcagc ttgaagacgg gcatgaatgt ttgcttcgtc gagtgatcag cagcgatggt
    10201 cgctcccgtg gtttcatcaa cggtacagct gttcctctgt cacaactgcg cgaactgggt
    10261 cagttgctga ttcagatcca tggtcagcac gctcatcaat tactcaccaa acctgagcac
    10321 caaaaattcc tgcttgatgg ctatgccaat gaaacctctc tactgcagga aatgaccgca
    10381 cgttatcagt tgtggcatca aagctgccgt gacctcgcgc atcatcaaca gttaagtcag
    10441 gaacgcgccg cccgtgcgga actgctgcaa taccaattaa aagaacttaa cgaatttaat
    10501 ccgcagcccg gagagtttga acaaatcgac gaagagtaca aacgtctggc gaacagcggt
    10561 caattgctga ccaccagcca gaatgcattg gcattaatgg ccgacggtga agacgcaaac
    10621 ctgcaaagtc agctttacac ggctaaacaa ctggtgagcg aattgattgg catggacagc
    10681 aaactgtccg gcgtacttga tatgctggaa gaagctacca tccagattgc tgaagccagc
    10741 gatgaactgc gccactactg cgatcgtctg gatctcgatc ccaaccgact atttgaactt
    10801 gaacagcgca tctcaaaaca gatttcgctg gcacgtaaac atcacgtcag ccctgaggca
    10861 ttgccacagt attaccagtc gctactggaa gaacagcagc aactggacga tcaggccgac
    10921 tcacaagaaa cgcttgcgct ggcggtaacg aaacatcatc agcaggcact ggaaatcgcg
    10981 cgcgcattac accaacaacg ccagcaatat gcagaagaac ttgcacagct gatcaccgac
    11041 agtatgcatg cgctctcaat gccgcatggg cagtttacga tcgatgttaa atttgacgag
    11101 catcacctgg gcgctgacgg tgccgatcgt attgagtttc gggtaaccac caacccaggt
    11161 cagccaatgc agcctattgc caaagtcgca tccggtggtg aattgtcccg catcgcactg
    11221 gcaatccagg tcatcacggc gcgtaaaatg gaaaccccgg cactgatttt tgatgaagtg
    11281 gatgtaggta ttagcggtcc aacagcggca gttgtcggca aactgctgcg tcaactcggc
    11341 gaatcaactc aggtgatgtg tgttacccac ctgccacaag tcgcgggatg tggtcatcaa
    11401 cactattttg tcagcaaaga aaccgatggt gcgatgacag aaacgcatat gcaatccctg
    11461 aataaaaaag cgcggttaca agagctggcg cgcctgcttg gtggcagtga agtcacacgt
    11521 aatacactgg cgaatgcgaa agaactgctt gcagcgtaaa cttttttcct gcttcacggt
    11581 cagagtaaac agcaaaacgc cgtaagaccg gaaagcaaaa ggttttaaag tgatgaaagg
    11641 tctattatca tcggcatatt acagatgagc cacgtactgc tcgggcccga aaaggaatca
    11701 aatcactatg cgctgtaaaa cgctgactgc tgcagcagca gtactattga tgttgaccgc
    11761 aggctgttcc actctggagc gagtggttta ccgtcctgac atcaaccagg ggaactatct
    11821 gaccgctaac gacgtatcca aaatacgtgt tggcatgacg caacaacaag ttgcgtacgc
    11881 attgggtaca ccgctgatgt ccgatccatt tggtacgaat acctggttct atgtcttccg
    11941 ccagcaacca ggtcatgaag gtgtaacgca gcaaacgctg acgctgacct ttaacagtag
    12001 cggtgtgttg accaatattg ataacaaacc tgcgctgagt ggtaactaat aataaagttg
    12061 ctctcaaaga cgttaaaaaa ggtgctcaat gagcaccttt tttctgtctg ttatttattc
    12121 gctgattttt ctgctcgttg cctgcgaagc tctttcggat cggcaatgag agggcgataa
    12181 atctccaccc gatcgccatc atgcacacta tcgcttagtt ttgccggacg gctgtaaatg
    12241 ccgactttgt ttttagttaa atcgatatcg gtacgcaatt ccagcaagcc actggcgcga
    12301 atagcttctt caaccgtcgc gccctcctgc agcgtcaccc gctgcaggta ctgcttctca
    12361 ggtagcgcat aagccacctc aacggcaatt ttacctggca ctgtaaacct ctttcgcacg
    12421 aaccgtaaaa gcctggacca tattagacgc cagctcttta aacacgcgac caaaggcgag
    12481 ttcaatcaac ttattggtaa actcaaagtc gagatgaaac tcgatacgac acgcctcctg
    12541 gctcagcggc gtaaacttcc atccaccaat caatttcttg aacggcccat ccaccagatt
    12601 cataagaata ctttggttac tggtcaactg gttgcgggta gtaaacgttt tgctgatccc
    12661 agccttagag acatctaccg ccgcagtcat ctgcccagga gtggactcca gaatccgact
    12721 tccggtacaa cccggcaaaa actgaggata agactgaacg tcattcacta actgatacat
    12781 ttgctccgcg ctgtagggta ccagtgcggt ccggctaatc tgaggcataa caatttccat
    12841 caacaaaaat ccaacaaata atatcattta tcctgctgta aaaaaaacgc tatcccggcg
    12901 ctgggtaaca tcgggttcat gctaagatag agccttgtcc cccgcaggat tgatatgggg
    12961 tgttttcgat ttcagattac cgatgattca cgacgcttat gacgaagaaa aaagcacata
    13021 aacctggttc agcgaccatc gcgcttaaca agcgcgcccg tcacgaatac tttatcgaag
    13081 aagagttcga agcgggactt gccctgcaag gcagggaggt taaatccctg cgcgcaggaa
    13141 aagccaatat cagcgacagc tacgtccttc tgcgtgacgg agaggcattt ctgtttggcg
    13201 ctaacatcac gccaatggcc gtggcctcca cgcatgtggt gtgcgatcct acccgtaccc
    13261 gcaagttact tctcaaccaa cgcgaactgg actcattgta cggtcgcgtc aatcgagaag
    13321 gctataccgt agtggcgctc tccctgtact ggaaaaatgc ctggtgcaaa gtgaaaatcg
    13381 gcgtcgccaa aggtaaaaaa cagcacgata aacgttcaga tatcaaagaa cgcgaatggc
    13441 aggtggataa agcacgtatc atgaaaaacg cccaccgtta aacctgcact ccaattattg
    13501 accagttcct caccgcgcct ccctctccgg cggcgcgaat gaacatctta ttggctatca
    13561 catccgacac aaatgttgcc atcccattgc ttaatcgaat aaaaatcagg ctacatgggt
    13621 gctaaatctt taacgataac gccattgagg ctggtcatgg cgctcataaa tctggtatac
    13681 ttacctttac acattggggc tgattctgga ttcgacggga tttgcgaaac ccaaggtgca
    13741 tgccgagggg cggttggcct cgtaaaaagc cgcaaaaaat agtcgcaaac gacgaaaact
    13801 acgctttagc agcttaataa cctgcttaga gccctctctc cctagcctcc gctcttagga
    13861 cggggatcaa gagaggtcaa acccaaaaga gatcgcgtgg aagccctgcc tggggttgaa
    13921 gcgttaaaac ttaatcaggc tagtttgtta gtggcgtgtc cgtccgcagc tggcaagcga
    13981 atgtaaagac tgactaagca tgtagtaccg aggatgtagg aatttcggac gcgggttcaa
    14041 ctcccgccag ctccaccaaa attctccatc ggtgattacc agagtcatcc gatgaagtcc
    14101 taagagcccg cacggcgcaa gccctgcggg cttttttgtg ccctcaattt gtcccgcgaa
    14161 gtccgaagaa aactaattaa atccgatcct tttaggcacc ttgttaggca cctcataaag
    14221 ctttattgtt ttttgaggtg cctaaaacta tggaaacccg gcaatggcaa gacaaaccaa
    14281 acctctatcc gttaaagaaa tagaatcagc caaacccaag gaggcggact acgttctcta
    14341 tgatggcgat ggccttgagc tactcattaa atccagcggg agtaaaatct ggcagtttcg
    14401 ctacattcgc cctgtcacca agaaacgagc aaagaagagc ataggctcct acccgtcagt
    14461 tacccttgcc gatgccagaa actaccgtgc agagtcccgc tcactactgg ctaaacagat
    14521 cgatccgcag gaacatcagc aagaacaatt gcgcagttcg ctggaagcca aaaccaacac
    14581 tttccaactc gtagctgaac gttggtggaa tgtgaagaaa gccagtgtga cagaggacta
    14641 tgcggaagat atctggcgct ctcttgaaag agacgtcttt cctgcgattg gcgacgttag
    14701 cgttacagat attaaagctc atacactggt tcaggccgta caaccggttc aggccagagg
    14761 agcactggaa actgttcgtc gcctgtgcca acgtattaat gaggtcatga tctatgccca
    14821 gaacacaggg ctgattgatg ctgttcccag cgttaatatc ggtaaagcct tcgagaagcc
    14881 tcagaaaaag aacatgccca gcattcgacc ggatcagcta cctcagttaa tgcagacgat
    14941 gcgaacagcc agcattagcc tttccacacg ctgcctgttc atgtggcaac ttcttactat
    15001 tacccgccct gccgaagcgg ctgaagctct ctgggaagag gtagacatag aagcgcgaga
    15061 gtggaagatt cctgcagcac gcatgaaaat gaaccgcgac catactgttc cattgtcaga
    15121 tgaagcaatt gcgatactag agatgatgaa gccgttaagt ggaaatcgag aatttatctt
    15181 tcccagccgc atcaagccaa accagccgat gaacagtcag accgtaaacg catcgctaaa
    15241 acgcgcaggt tttggtgggg tgctcgtttc acacggcctg cgatctatcg ccagtacagc
    15301 ccttaatgag cagggatttc cacctgatgt tattgaggct gcacttgctc atgtggataa
    15361 gaatgaggtt cgtcgtgcgt ataaccgtag tgattatctt gagcagcgac ggcctatgat
    15421 gcagtggtgg gctgattttg tgatggctgc agatcacggt agtatgattg aaggagggat
    15481 aaaggcaatg cggttagttg gatgacatgt cgtagctaaa acccgttctg tttttgggta
    15541 gattaacctg aaggtctgca attttaaatg acgctgaaag aagttaaacc ctgctcttaa
    15601 gcagggtttt tatgatttat tctaattttg gttttgaatc tttctatttt aaatcagcct
    15661 ttgcggctcg aatatctgcg ttttttgctg agtattccca ttcgtcagcg attctaaata
    15721 gcattgcaga agtacggacg cagtggggca ttgaatttgc ccattctcgg tactgctcag
    15781 ctaatatcct ttcttggttt ccaccttcgt aacgcatacg agcaaatacc ccccttttat
    15841 tgtacctacc aatttgtata ccttgctcta actcatcaga agataatatt tcaatgatgt
    15901 gccgaattgc ttcatgtggc caggaattat ctactgagct attaggggca tgtgccagaa
    15961 tttttcctat tacatgatca gtgatttctt ggcgatgatg caattttgct aaatggcgta
    16021 cattctcaca ccaatcttca agtttatctt gatcaatttc attgtctatc tgccctggta
    16081 gtattcgtaa tttttcaagt aatctgtata tagaagtagc tcttttaact tccaactccg
    16141 atggttctgt ttgttcatct tcgtcactac gatatacaat acatattgct tctataaaaa
    16201 cctctggctt tttcatcatt agacgatgca ggataagtgg ctcatcgcta tccggaaaac
    16261 aaggcaagta ggtcatttct ttaaatgcca aatctgtttc agaaacatcg ttacgttgtt
    16321 tgagttcatc aaaaactttt tttacatagt acgatagcat tgtatcaaat tggatatcct
    16381 ggctatttat ttctttaacg actatatcta gaagatataa aagtgttgta gatggaatct
    16441 cagaaaggcg ttgatttgct gatataatag cagcaagacc ccggcccctt tctatatatt
    16501 tatccataag aacaaataaa tccgaagttt tacccatcat tgcaatgggt tgtttttgca
    16561 accaatattt ttcgttgatg ttatcttcaa acccttcaat aatgctccat atctcttgtg
    16621 agtctcttaa cgatgctaag attttcccag ccctatcagg ggtaatttta aactgtttaa
    16681 aatacacttt tattttatta agccattcag caccaaagca ttcaacacca tattgcatta
    16741 acaacccaca aacttcatca atattttttt tgttgttaat aagcattaca aacaaatcat
    16801 ttaatttttc ttcatccaac gagagtgctg atatatgcct tgctgcaata aaaacattat
    16861 taacttgttg aaaaaggtct ttcaccccag acaaacctaa agtaaagtat atttccctaa
    16921 gtttttcact tcgcatttct tcgacagaag aaaaaattcc gccagcattt tcaattgact
    16981 cttcaatatc agaatcccaa tcattgaaaa tccataaact ggctctaacc atgtcaattg
    17041 gtttataatt atcaagtatt ttcgctattt tttctataga ctcaaattta aatgcccagt
    17101 tcgcatctga atatttttta tggcgagaat actcatgacg caaagcctcc catacgatga
    17161 actgatcctc ttcagtttgt tgagaaaggc aaagttcaag atgagaaagt gtttcatcta
    17221 ttgcattctc agggaatgag cttaaatgag agattaggat ttcccatctt gttgggagta
    17281 tacctgcaag tttaattgct tcttggataa taaagatttg cccctcccaa acaacgcccc
    17341 acgttagttt ttctacatct ttatccgact ctctgaactt cattttttgg ttttgatcag
    17401 aggtatcatg ggagcgagga aggagatttt gtaacaaact ccacccaata ctaggaacaa
    17461 tagtgataat tttttttata attgcatttc taacttttac tggtgcccat gtattaggag
    17521 accatgccag aaaaatggtt cttaaactat taagagggcg atctgagtaa gttcctccgg
    17581 gatctattac agcgagtttt gcaagacaga ttgcagcgcg taatagatat gtttgttccc
    17641 aagccaaggc ttccaatgcc cattttaatc catgataatg acttcgagga gttaacagcc
    17701 ctttatcttc attgaatatt ggagcaatca tttccccatt gcccttaagc aattgctcaa
    17761 gggcatcaag gaaagggcca ggggcagctt ctgccagcag cggaagttga tctcgcaaac
    17821 taacaaatag tcgatggtcg ttagcaagtc ccggaatact ctgaactatt ttgttaacaa
    17881 aatcttgggg tgtcatacca gtaacccgga attcggcctg ttcatgtaat
//
LOCUS       DAPGUL010000090        17690 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.091, whole genome shotgun sequence.
ACCESSION   DAPGUL010000090 DAPGUL010000000
VERSION     DAPGUL010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17690
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.091"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            84..1223
                     /gene="arnB"
                     /locus_tag="RHX21_003297"
     CDS             84..1223
                     /gene="arnB"
                     /locus_tag="RHX21_003297"
                     /EC_number="2.6.1.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_024188371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-4-amino-4-deoxy-L-arabinose
                     aminotransferase"
                     /protein_id="HDV1988444.1"
                     /translation="MSEFLPFSRPAMGVEELAAVKEVLESGWLTTGPKNQALEQAFCQ
                     LTGNQHAIAVSSATAGMHITLMALEIGKGDEVITPSLTWVSTLNMISLLGATPVMVDV
                     DRDTLMVTPEAIESAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVG
                     TYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDR
                     QTWGRAPQAEVLTPGYKYNLTDINAAIALTQLAKLEHLNTRRREIAQQYQQALAALPF
                     QPLSLPAWPHVHAWHLFIIRVDEQRCGISRDALMEALKERGIGTGLHFRAAHTQKYYR
                     ERFPTLSLPNTEWNSERICSLPLFPDMTTADADRVITALQQLAGQ"
     gene            1227..2195
                     /gene="arnC"
                     /locus_tag="RHX21_003298"
     CDS             1227..2195
                     /gene="arnC"
                     /locus_tag="RHX21_003298"
                     /EC_number="2.4.2.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate
                     4-deoxy-4-formamido-L-arabinose transferase"
                     /protein_id="HDV1988445.1"
                     /translation="MFEIHPVKKVSVVIPVYNEQESLPELIRRTTTACESLGKEYEIL
                     LIDDGSSDNSAHMLVEASQAENSHIVSILLNRNYGQHSAIMAGFSHVTGDLIITLDAD
                     LQNPPEEIPRLVAKADEGYDVVGTVRQNRQDSWFRKTASKMINRLIQRTTGKAMGDYG
                     CMLRAYRRHIVDAMLHCHERSTFIPILANIFARRAIEIPVHHSEREFGESKYSFMRLI
                     NLMYDLVTCLTTTPLRMLSLLGSIIAIGGFSIAVLLVILRLTFGPQWAAEGVFMLFAV
                     LFTFIGAQFIGMGLLGEYIGRIYTDVRARPRYFVQQVIRPSSKENE"
     gene            2195..4177
                     /gene="arnA"
                     /locus_tag="RHX21_003299"
     CDS             2195..4177
                     /gene="arnA"
                     /locus_tag="RHX21_003299"
                     /EC_number="1.1.1.305"
                     /EC_number="2.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-4-amino-4-deoxy-L-arabinose
                     formyltransferase/UDP-glucuronic acid oxidase ArnA"
                     /protein_id="HDV1988446.1"
                     /translation="MKTVVFAYHDMGCLGIEALLAAGYEISAIFTHTDNPGEKAFYGS
                     VARLAAERGIPVYAPDDVNHPLWVERIAQLSPDVIFSFYYRHLICDEILQLAPAGAFN
                     LHGSLLPKYRGRAPLNWVLVNGETETGVTLHRMVKRADAGAIVAQLRIAIAPDDIAIT
                     LHHKLCHAARQLLEQTLPAIKHGNILEIAQRENEATCFGRRTPDDSFLEWHKPASVLH
                     NMVRAVADPWPGAFSYVGNQKFTVWSSRVHPHASKAQPGSVISVAPLLIACGDGALEI
                     VTGQAGDGITMQGSQLAQTLGLVQGSRLNSQPACTARRRTRVLILGVNGFIGNHLTER
                     LLREDHYEVYGLDIGSDAISRFLNHPHFHFVEGDISIHSEWIEYHVKKCDVVLPLVAI
                     ATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPSTSEVYGMCSDKYFDEDHSN
                     LIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFNWMGPRLDNLNAARIGS
                     SRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENAGNRCDGEIINIG
                     NPENEASIEELGEMLLASFEKHPLRHHFPPFAGFRVVESSSYYGKGYQDVEHRKPSIR
                     NAHRCLDWEPKIDMQETIDETLDFFLRTVDLTDKPS"
     gene            4174..5064
                     /locus_tag="RHX21_003300"
     CDS             4174..5064
                     /locus_tag="RHX21_003300"
                     /EC_number="3.5.1.n3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-deoxy-4-formamido-L-arabinose-
                     phosphoundecaprenol deformylase"
                     /protein_id="HDV1988447.1"
                     /translation="MTKVGLRIDVDTFRGTREGVPRLLEILSKHNIQASIFFSVGPDN
                     MGRHLWRLVKPQFLWKMLRSNAASLYGWDILLAGTAWPGKEIGHANADIIREAAKHHE
                     VGLHAWDHHAWQARSSNWDRQTMIDDIARGLRTLEEIIGQPVTCSAAAGWRADQKVIE
                     AKEAFHLRYNSDCRGAMPFRPLLESGNPGTAQIPVTLPTWDEVIGRDVKAEDFNGWLL
                     NRILRDKGTPVYTIHAEVEGCAYQHNFVDLLKRAAQEGVTFCPLSELLSETLPLGQVV
                     RGNIAGREGWLGCQQIAGSR"
     gene            5064..6716
                     /gene="arnT"
                     /locus_tag="RHX21_003301"
     CDS             5064..6716
                     /gene="arnT"
                     /locus_tag="RHX21_003301"
                     /EC_number="2.4.2.43"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A)
                     4-amino-4-deoxy-L-arabinosyltransferase"
                     /protein_id="HDV1988448.1"
                     /translation="MKSVRYLIGLFAFIACYYLLPISTRLLWQPDETRYAEISREMLA
                     SGDWIVPHLLGLRYFEKPIAGYWINSIGQWLFGANNFGVRAGVIFATLLTAALVTWFT
                     LRLWRDKRLALLATVIYLSLFIVYAIGTYAVLDPFIAFWLVAGMCSFWLAMQAQTWKG
                     KSAGFLLLGITCGMGVMTKGFLALAVPVLSVLPWVATQKRWKDLFIYGWLAVISCVLT
                     VLPWGLAIAQREPDFWHYFFWVEHIQRFALDDAQHRAPFWYYVPVIIAGSLPWLGLLP
                     GALYTGWKNRKHSATVYLLSWTIMPLLFFSVAKGKLPTYILSCFASLAMLMAHYALLA
                     AKNNPLALRINGWINIAFGVTGIIATFVVSPWGPMNTPVWQTFESYKVFCAWSIFSLW
                     AFFGWYTLTNVEKTWPFAALCPLGLALLVGFSIPDRVMEGKHPQFFVEMTQESLQPSR
                     YILTDSVGVAAGLAWSLQRDDIIMYRQTGELKYGLNYPDAKGRFVSGDEFANWLNQHR
                     QEGIITLVLSVDRDEDINSLAIPPADAIDRQERLVLIQYRPK"
     gene            6713..7048
                     /gene="arnE"
                     /locus_tag="RHX21_003302"
     CDS             6713..7048
                     /gene="arnE"
                     /locus_tag="RHX21_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
                     flippase subunit ArnE"
                     /protein_id="HDV1988449.1"
                     /translation="MIWLTLVFASLLSVAGQLCQKQATCFVAINKRRKHIVLWLGLAL
                     ACLGLAMVLWLLVLQNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSPRHWCGVAFIIG
                     GIVILGSTV"
     gene            7048..7434
                     /gene="arnF"
                     /locus_tag="RHX21_003303"
     CDS             7048..7434
                     /gene="arnF"
                     /locus_tag="RHX21_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311173.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
                     flippase subunit ArnF"
                     /protein_id="HDV1988450.1"
                     /translation="MGLIWGLFSVIIASVAQLSLGFAASHLPPMTHLWDFIAALLAFG
                     LDARILLLGLLGYLLSVFCWYKTLHKLALSKAYALLSMSYVLVWIASMVLPGWEGTFS
                     LKALLGVACIMSGLMLIFLPTTKQRY"
     gene            complement(7428..7694)
                     /gene="pmrD"
                     /locus_tag="RHX21_003304"
     CDS             complement(7428..7694)
                     /gene="pmrD"
                     /locus_tag="RHX21_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416762.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction protein PmrD"
                     /protein_id="HDV1988451.1"
                     /translation="MEWLVKKSCCNKQDNRHVLMLCDAGGAIKMIAEVKSDFAVKVGD
                     LLSPLQNALYCINREKLHTVKVLSASSYSPDEWERQCTAAGKTQ"
     gene            complement(7804..9159)
                     /gene="menE"
                     /locus_tag="RHX21_003305"
     CDS             complement(7804..9159)
                     /gene="menE"
                     /locus_tag="RHX21_003305"
                     /EC_number="6.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate--CoA ligase"
                     /protein_id="HDV1988452.1"
                     /translation="MIFSDWPWRHWRQVRGEAIALRLNDEQLNWRELCARVDELASGF
                     AAQGVVEGSGVMLRAWNTPQTLLAWLALLQCGARVLPVNPQLPQPLLEELLPNLTLQF
                     ALVPDGENTFPALTSLHIQRVEGAHAATWQPTRLCSMTLTSGSTGLPKAAVHTYQAHL
                     ASAEGVLSLIPFGDHDDWLLSLPLFHVSGQGIMWRWLYAGARMTVRDKQPLEQMLAGC
                     THASLVPTQLWRLLVNRSSVSLKAVLLGGAAIPVELTEQAREQGIRCFCGYGLTEFAS
                     TVCAKEADGLADVGSPLPGREVKIVNNEVWLRAASMAEGYWRNGQLVSLVNDEGWYAT
                     RDRGEMHNGKLTIVGRLDNLFFSGGEGIQPEEVERVIAAHPAVLQVFIVPVADKEFGH
                     RPVAVVEYDQQTVDLGEWVKDKLARFQQPVRWLTLPPELKNGGIKISRQALKEWVQRQ
                     Q"
     gene            complement(9156..10118)
                     /gene="menC"
                     /locus_tag="RHX21_003306"
     CDS             complement(9156..10118)
                     /gene="menC"
                     /locus_tag="RHX21_003306"
                     /EC_number="4.2.1.113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate synthase"
                     /protein_id="HDV1988453.1"
                     /translation="MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGE
                     ISPLPGFSQETWEEAQSVLLAWVNNWLAGDCELPQMPSVAFGVSCALAELADTLPQAA
                     NYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAIPDLHLRL
                     DANRAWTPLKGQQFAKYVNPDYRHRIAFLEEPCKTRDDSRAFARETGIAIAWDESLRE
                     PDFAFVAEEGVRAVVIKPTLTGSLEKVREQVQAAHALGLTAVISSSIESSLGLTQLAR
                     IAAWLTPDTIPGLDTLDLMQAQQVRRWPGSTLPVVEVDALERLL"
     gene            complement(10118..10975)
                     /gene="menB"
                     /locus_tag="RHX21_003307"
     CDS             complement(10118..10975)
                     /gene="menB"
                     /locus_tag="RHX21_003307"
                     /EC_number="4.1.3.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001641973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA synthase"
                     /protein_id="HDV1988454.1"
                     /translation="MIYPDEAMLYAPVEWHDCSEGFEDIRYEKSTDGIAKITINRPQV
                     RNAFRPLTVKEMIQALADARYDDNIGVIILTGAGDKAFCSGGDQKVRGDYGGYKDDSG
                     VHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMMCDLTIAADNAIFGQTGPKVG
                     SFDGGWGASYMARIVGQKKAREIWFLCRQYDAKQALDMGLVNTVVPLADLEKETVRWC
                     REMLQNSPMALRCLKAALNADCDGQAGLQELAGNATMLFYMTEEGQEGRNAFNQKRQP
                     DFSKFKRNP"
     gene            complement(10990..11748)
                     /gene="menH"
                     /locus_tag="RHX21_003308"
     CDS             complement(10990..11748)
                     /gene="menH"
                     /locus_tag="RHX21_003308"
                     /EC_number="4.2.99.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-6-hydroxy-2,
                     4-cyclohexadiene-1-carboxylate synthase"
                     /protein_id="HDV1988455.1"
                     /translation="MILHAQAKHGKPGLPWLVFLHGFSGDCHEWQEVGEAFADYSRLY
                     VDLPGHGGSAAISVDGFDDVTDLLRKTLVSYNILDFWLVGYSLGGRVAMMAACQGLAG
                     LCGVIVEGGHPGLQNAEQRAERQRSDRQWAQRFRTEPLTAVFADWYQQPVFASLNDDQ
                     RRELVALRSNNNGATLAAMLEATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAA
                     ELAADCHVIPRAGHNAHRENPAGVIASLAQILRF"
     gene            complement(11745..13415)
                     /gene="menD"
                     /locus_tag="RHX21_003309"
     CDS             complement(11745..13415)
                     /gene="menD"
                     /locus_tag="RHX21_003309"
                     /EC_number="2.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-5-enolpyruvyl-6-hydroxy-3-
                     cyclohexene-1-carboxylic-acid synthase"
                     /protein_id="HDV1988456.1"
                     /translation="MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAEN
                     STFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLIL
                     LTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTRDIPARWLVSTIDHALGTLH
                     AGGVHINCPFAEPLYGEMDDTGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWR
                     QKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSEL
                     QQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWL
                     ELHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGEAQLAHRICDYLPEQGQLFVGNSL
                     VVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLN
                     ALALLRQVSAPLVLIVVNNNGGQIFSLLPTPQSERERFYLMPQNVHFEHAAAMFELKY
                     HRPQNWQELETAFADAWRTPTTTVIEMVVNDTDGAQTLQQLLAQVSHL"
     gene            complement(13504..14799)
                     /gene="menF"
                     /locus_tag="RHX21_003310"
     CDS             complement(13504..14799)
                     /gene="menF"
                     /locus_tag="RHX21_003310"
                     /EC_number="5.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416768.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase MenF"
                     /protein_id="HDV1988457.1"
                     /translation="MQSLTTALENLLRHLSQEIPATPGIRVIDIPFPLKDAFDALSWL
                     ASQQTYPQFYWQQRNGDEEAAVLGAITRFTSLDQAQRFLRQHPEHADLRIWGLNAFDP
                     SQGNLLLPRLEWRRCGGKATLRLTLFSESSLQHDAIQAKEFIATLVSIKPLPGLHLTT
                     TREQHWPDKTGWTQLIELATKTIAEGELDKVVLARATDLHFASPVNAAAMMAASRRLN
                     LNCYHFYMAFDGENAFLGSSPERLWRRRDKALRTEALAGTVANNPDDKQAQQLGEWLM
                     ADDKNQRENMLVVEDICQRLQADTQTLDVLPPQVLRLRKVQHLRRCIWTSLNKADDVI
                     CLHQLQPTAAVAGLPRDLARQFIARHEPFTREWYAGSAGYLSLQQSEFCVSLRSAKIS
                     GNVVRLYAGAGIVRGSDPEQEWQEIDNKAAGLRTLLQME"
     gene            complement(14878..15183)
                     /gene="elaB"
                     /locus_tag="RHX21_003311"
     CDS             complement(14878..15183)
                     /gene="elaB"
                     /locus_tag="RHX21_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein ElaB"
                     /protein_id="HDV1988458.1"
                     /translation="MSNQFGDTRIDDDLTLLSETLEEVLRSSGDPADQKYVELKARAE
                     KALDDVKKRVSQASDSYYYRAKQAVYRADDYVHEKPWQGIGVGAAVGLVLGLLLARR"
     gene            complement(15238..15699)
                     /locus_tag="RHX21_003312"
     CDS             complement(15238..15699)
                     /locus_tag="RHX21_003312"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDV1988459.1"
                     /translation="MIEWQDLHHSELSVSQLYALLQLRCAVFVVEQNCPYQDIDGDDL
                     TGDNRHILGWKNDELVAYARILKSDDDLEPVVIGRVIVSEALRGEKVGQQLMSKTLET
                     CTHHWPDKPVYLGAQAHLQNFYQSFGFIPVTEVYEEDGIPHIGMAREVIQA"
     gene            15764..16681
                     /gene="rbn"
                     /locus_tag="RHX21_003313"
     CDS             15764..16681
                     /gene="rbn"
                     /locus_tag="RHX21_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416771.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease BN"
                     /protein_id="HDV1988460.1"
                     /translation="MELIFLGTSAGVPTRTRNVTAILLNLQHPTQSGLWLFDCGEGTQ
                     HQLLHTAFNPGKLDKIFISHLHGDHLFGLPGLLCSRSMSGIIQPLTIYGPQGIREFVE
                     TALRISGSWTDYPLEIVEIGAGEILDDGLRKVTAYPLEHPLECYGYRIEEHDKPGALN
                     AQALKAAGVPPGPLFQELKAGKTITLEDGRQINGADYLAAPVPGKALAIFGDTGPCDA
                     ALDLAKGVDVMVHEATLDITMEAKANSRGHSSTRQAATLAREAGVGKLIITHVSSRYD
                     DKGCQHLLRECRSIFPATELANDFTVFNV"
     gene            16869..17690
                     /locus_tag="RHX21_003314"
                     /pseudo
     CDS             16869..17690
                     /locus_tag="RHX21_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416772.1"
                     /note="ElaD; specific cysteine protease which targets
                     ubiquitin and ubiquitin-like proteins covalently bound to
                     target proteins; SseL in Salmonella is required for
                     macrophage killing and virulence, and it is secreted by
                     the salmonella pathogenicity island 2 type III secretion
                     system; frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="deubiquitinase"
BASE COUNT         4187 a         4759 c         4455 g         4289 t
ORIGIN      
        1 tttcgctcca aatggcaaaa tatacacaac actctttata gcaaatataa gtggacaggt
       61 attcaatggc ggaaggaaaa gcaatgtcag aatttttgcc tttttcgcga ccagcaatgg
      121 gcgtggagga actcgctgca gttaaagagg ttctcgaatc cggttggctc acaaccggtc
      181 cgaagaatca ggcgcttgag caagcctttt gccagttgac gggaaatcag catgccatcg
      241 cggtcagttc agccaccgcc ggaatgcata tcacgctaat ggcgttggaa attggcaagg
      301 gcgatgaagt gattacgcct tccctgacct gggtttcaac cctcaatatg atttccttgt
      361 tgggtgcaac gccggtaatg gtggatgtcg accgcgatac gctgatggtc acgcctgaag
      421 cgatcgagtc agccataacg ccacgcacta aagccatcat tccggtgcat tatgccggtg
      481 cgccagcaga tattgacgcc attcgcgcca ttggcgaacg ttacggcatc gcagttatcg
      541 aagatgctgc ccatgccgtc ggtacgtatt acaaagggcg acatattggc gcaaaaggta
      601 ccgctatttt ttcatttcat gccattaaaa atattacctg tgcggaaggt ggcctgattg
      661 taactgataa tgaaaacctt gcccgccagc tacggatgct gaaatttcac ggtctgggtg
      721 tcgatgccta tgacagacaa acctggggcc gtgcaccgca ggctgaagtc ttaacaccgg
      781 gctataagta caatctgacc gatattaacg ccgcaattgc cctgacacag ttagcaaaat
      841 tagagcacct caacacccgt cggcgcgaaa ttgcccagca atatcagcaa gcactggcag
      901 ctctcccctt tcagccatta agccttcccg cctggccgca cgttcacgcc tggcatctgt
      961 ttattattcg tgtcgatgaa caacgttgtg gtatcagtcg cgatgcgttg atggaagcgt
     1021 taaaagaacg aggcattggt accgggttac atttccgcgc cgctcacaca caaaaatatt
     1081 atcgcgagcg ttttcccacg ctgtcgttac cgaataccga atggaatagc gaacgcatct
     1141 gttctttgcc gctgttcccg gatatgacta ccgccgatgc cgaccgtgtc atcacagccc
     1201 ttcagcaact cgcaggacaa taagccatgt ttgaaatcca ccctgttaag aaagtctcgg
     1261 tggttattcc cgtttataac gagcaggaaa gcttaccgga attaatcagg cgcaccacca
     1321 cagcctgtga atcgttgggg aaagagtatg agatcctgct gattgatgac ggcagtagcg
     1381 ataattccgc gcatatgctg gtcgaagcct cacaagcgga gaacagccat attgtgtcta
     1441 ttttgcttaa ccgcaattac gggcaacatt cagcgattat ggcgggattc agtcacgtta
     1501 ccggcgactt aattattacc cttgatgccg atctccagaa tccgccagaa gaaatccccc
     1561 gcctggtggc aaaagccgat gaaggttacg acgtggtagg gactgtacgc cagaaccgcc
     1621 aggacagctg gtttcgtaaa acagcttcga agatgattaa ccggcttatt cagcgcacca
     1681 ccggcaaagc gatgggtgac tacggttgta tgctgcgcgc ctatcgccgt catattgtcg
     1741 atgcgatgtt gcactgccat gaacgtagca cctttatccc gattctggcg aatatcttcg
     1801 cccgccgtgc cattgaaatt ccagtacatc attccgagcg tgagtttggt gaatccaaat
     1861 acagttttat gcgcctgatt aatttgatgt acgacctggt gacctgcctt accacaacgc
     1921 cgctacgtat gctgagtctg ctcggcagca ttattgcgat tggaggtttt agcattgcgg
     1981 tgctgctggt gattttacgc ctgaccttcg gaccacaatg ggcggcagaa ggcgtcttta
     2041 tgctatttgc cgtgctgttt acttttattg gcgctcagtt tatcggcatg ggattactcg
     2101 gtgaatatat cggcaggatc tacaccgatg tccgcgcccg cccccgctat tttgttcagc
     2161 aagttatccg tccatccagc aaggaaaatg aataatgaaa accgtcgttt ttgcctacca
     2221 cgatatggga tgcctcggta ttgaagctct gctggctgcc ggttacgaaa ttagcgccat
     2281 ttttacccat accgataatc ccggtgaaaa agccttttat ggttcggtgg ctcgtctggc
     2341 agcggaaaga ggcattccgg tttatgcgcc ggatgacgtt aatcatccgc tgtgggtgga
     2401 acgcattgcc caactgtcgc cagatgtgat tttctctttt tattatcgcc atcttatttg
     2461 cgacgaaatt ttgcagctcg ctcccgcagg tgcatttaat ctgcatggtt cgctgttacc
     2521 aaaatatcgt ggtcgcgcgc cgctgaactg ggtgctggtc aacggtgaaa cggaaactgg
     2581 cgttacattg caccgaatgg tgaaacgtgc cgatgccggg gccattgtgg cgcaactgcg
     2641 cattgccatt gcgccagacg atatcgctat tacgctgcat cataaattgt gccatgccgc
     2701 gcgccagcta ctggaacaga cattacccgc cattaaacac ggtaatattc tggaaatcgc
     2761 ccagcgcgaa aacgaagcca cctgttttgg tcgcagaacg ccggatgaca gtttccttga
     2821 atggcataaa ccggcatccg tactgcacaa catggtacgt gccgttgccg atccgtggcc
     2881 gggtgccttc agctatgttg gcaatcagaa attcaccgtc tggtcgtcgc gtgttcatcc
     2941 tcatgccagc aaagcacagc cggggagcgt gatttctgtt gcgccactgc tgattgcctg
     3001 tggcgatggc gcgctggaaa tcgtcaccgg acaggcgggc gacggcatta ctatgcaggg
     3061 ctcgcaatta gcgcagacgc tgggcctggt gcaaggttca cgcttgaata gccagcctgc
     3121 ctgcaccgcc cgacgccgta cccgggtact catcctcggg gtgaatggct ttattggcaa
     3181 ccatctgaca gaacgcctgc tgcgcgaaga tcattatgaa gtttacggtc tggatattgg
     3241 cagcgatgcg ataagccgtt ttctgaatca tccgcatttt cactttgttg aaggcgatat
     3301 cagtattcat tccgaatgga ttgagtatca tgtcaaaaaa tgtgatgtcg tcttgccgct
     3361 ggtggcgata gccacgccga ttgaatatac ccgcaacccg ctgcgcgtat ttgaactcga
     3421 ttttgaagag aatctgcgca ttatccgcta ctgcgtgaag taccgtaagc gaatcatctt
     3481 cccgtcaact tcagaagttt atgggatgtg tagcgataaa tacttcgatg aggaccattc
     3541 taatttaatc gtcggcccgg tgaataaacc acgctggatt tattcggtat caaaacaatt
     3601 acttgatcgg gtgatctggg cctatggcga aaaagagggt ttacagttca ccctcttccg
     3661 cccgtttaac tggatgggac cgcgactgga taaccttaat gcggcacgaa tcggcagctc
     3721 ccgcgctatt acgcaactca ttctcaatct ggtagaaggt tcaccgatta agctgattga
     3781 tggcggaaaa caaaaacgct gctttactga tattcgcgat ggtatcgagg cgttataccg
     3841 cattatcgaa aatgcgggaa atcgctgcga cggtgaaatt atcaacattg gcaatcctga
     3901 gaacgaagcg agcattgagg aactgggcga gatgctgctg gcgagcttcg aaaaacatcc
     3961 gctgcgccat catttcccac cgtttgcggg ctttcgcgtt gtcgaaagta gcagctacta
     4021 cggcaaagga tatcaggacg tagagcatcg taaaccgagc atccgcaatg cccaccgctg
     4081 cctggactgg gagccgaaaa ttgatatgca ggaaaccatc gacgaaacgc tggatttctt
     4141 cctgcgcacc gttgatctta cggataaacc atcatgacca aagtaggctt acgcattgat
     4201 gtcgatacct ttcgtggcac ccgtgaaggc gtgccgcgtc tgctggaaat cttgagtaag
     4261 cataatattc aggccagcat ttttttcagc gtcggcccgg acaatatggg ccgccatctc
     4321 tggcgactgg tgaagccaca gtttttgtgg aagatgctgc gctcaaatgc ggcatcgctt
     4381 tatggctggg atattttact ggcaggtacg gcctggccag gtaaagagat tggtcatgcc
     4441 aatgccgata tcattcgtga agcggctaaa catcacgaag tcggcctgca cgcctgggat
     4501 caccatgcct ggcaagcccg tagcagtaac tgggatcggc aaacaatgat cgacgatatt
     4561 gcacgcggtc ttcgcactct ggaagagatt atcggtcaac cggtaacctg ttctgccgct
     4621 gcgggctggc gtgccgacca gaaggtgatc gaagcaaaag aagcgttcca tttgcgctac
     4681 aacagcgatt gtcgtggggc catgccgttc cgtccattgc tcgaatcagg aaaccctggc
     4741 actgcgcaaa ttccggtgac cttacccacc tgggatgaag tgattggtcg ggatgtgaaa
     4801 gcagaagatt ttaacggttg gttactcaac cgcatcctgc gagataaagg cacgccggtt
     4861 tataccattc atgcagaagt tgaaggctgc gcttatcagc ataattttgt ggatctcctc
     4921 aaacgcgcag ctcaggaagg cgtgacattt tgccctttaa gcgaactgtt atcagagacg
     4981 ttgccgctcg gacaagttgt tcgcggaaat attgccggac gtgaaggctg gctgggttgc
     5041 caacaaattg cgggtagtcg ctgatgaaat cggtacgtta ccttatcggc ctcttcgcgt
     5101 ttattgcctg ctattacctg ttaccgatca gcacgcgtct gctctggcaa cccgatgaaa
     5161 cgcgttatgc ggaaatcagt cgagaaatgc tggcatccgg cgactggatt gtgccccatc
     5221 tgttagggct acgttatttc gaaaaaccca ttgccggata ctggattaac agcattgggc
     5281 aatggctatt tggcgcgaat aactttggtg tgcgggcagg cgttatcttt gcgaccctgt
     5341 taactgccgc gctggtgacc tggtttactc tgcgcttatg gcgcgataaa cgtctggctc
     5401 tactcgccac agtaatttat ctctcattgt ttattgtcta tgccatcggc acttatgccg
     5461 tgctcgatcc gtttattgca ttctggctgg tggcgggaat gtgcagcttc tggctggcaa
     5521 tgcaggcaca gacgtggaaa ggcaaaagcg caggattttt actgctggga atcacctgcg
     5581 gcatgggggt gatgaccaaa ggttttctcg cccttgccgt gccggtatta agcgtgctgc
     5641 catgggtagc gacgcaaaaa cgctggaaag atctctttat ttacggctgg ctggcggtta
     5701 tcagttgcgt actgacggtt ctcccttggg gactggcgat agcgcagcgg gagcctgact
     5761 tctggcacta ttttttctgg gttgagcata ttcaacgctt tgcactggat gatgcccaac
     5821 atagagctcc gttctggtac tacgtgccgg tcatcattgc cggtagcctg ccgtggctgg
     5881 gattactccc cggtgcactg tacacaggct ggaaaaaccg caagcattcc gcaaccgtct
     5941 atttgttgag ctggacgata atgccgctgc tgtttttctc cgtcgctaaa ggtaaattgc
     6001 ccacctatat tctttcctgc tttgcatctc tggcaatgct gatggcgcat tacgctttgc
     6061 tggcagcaaa aaataatcct ctggcgctgc ggattaatgg ctggattaac atcgcttttg
     6121 gcgtcactgg cattattgcc acatttgtgg tctccccgtg gggaccaatg aacacgccgg
     6181 tgtggcaaac cttcgagagc tataaagtct tttgtgcctg gtcgattttt tcgctatggg
     6241 catttttcgg ctggtacacc ttaacaaacg tcgaaaagac ctggcctttt gccgcgcttt
     6301 gcccgctggg gctggcgttg ctggtaggat tttcaattcc tgacagagtt atggaaggaa
     6361 aacatccgca attttttgtc gagatgacac aagaatcact tcagccaagc cgctatattc
     6421 ttactgatag cgtcggtgtt gccgcaggtc tggcatggag cctgcaacgc gatgacatca
     6481 tcatgtatcg ccagacaggt gagttgaaat acggccttaa ttatccggat gcgaaaggga
     6541 gatttgtcag cggtgatgag ttcgcaaact ggcttaatca acatcgtcag gaggggatta
     6601 ttactctcgt gctttcggtt gaccgcgatg aagatatcaa cagtctcgcc attccgcccg
     6661 cagatgccat cgatcgtcag gagcgtctgg tgctgattca gtatcgtccc aaatgatctg
     6721 gctaacatta gtctttgcca gcttgcttag cgttgccggg cagttgtgtc agaaacaggc
     6781 aacctgcttt gtggcgataa acaaacggcg caaacatatc gtgctgtggc tgggactggc
     6841 gctggcttgt cttggtcttg ccatggtgct ctggctgctg gtcttgcaga acgtaccggt
     6901 aggcattgcc tacccgatgt taagtctgaa ttttgtctgg gtgacgctgg ctgcagtaaa
     6961 actgtggcac gaaccggtat cgccgcgtca ctggtgtggg gtggcgttca ttattggtgg
     7021 cattgtgatc ctcgggagta cggtgtaatg ggcctgatat ggggattatt cagcgtcatt
     7081 attgcctcag ttgcgcaatt aagcctgggt tttgcggcaa gtcatctgcc gccgatgacg
     7141 cacttatggg attttatcgc ggctctgtta gcttttggcc tggatgcccg gatactgtta
     7201 ctcgggctgc tgggttatct gctttccgtt ttttgttggt ataaaacgct acataaactt
     7261 gcgctaagca aagcctatgc cttgctcagt atgagttatg tgctggtatg gattgcttca
     7321 atggtacttc ccggctggga agggactttt tcgctgaaag cactactggg agtagcctgt
     7381 attatgagcg ggttgatgct gattttcctg cccacgacaa aacaacgtta ctgagttttc
     7441 cctgccgctg tacactgccg ttcccactca tcggggctat aactgcttgc cgagaggact
     7501 ttcaccgtat gcagcttttc acgattaata caataaagcg cattctgcaa aggcgagagt
     7561 aaatccccca ctttcacggc gaagtcactc ttcacttcgg cgatcatttt tatcgcgccg
     7621 ccagcatcgc agagcataag tacatgtctg ttatcttgtt tattgcagca cgattttttg
     7681 accagccatt ccattgcatt atcctgtttg ctaagagttt tcacatcaat ttacagatta
     7741 acagataaac tctttatcaa cggcaatgga atggcagaaa tgagaagtga aacggagggt
     7801 taattattgc tgacgttgca cccactcttt tagcgcctga cgtgaaattt taataccgcc
     7861 gtttttcagc tccggcggta aagtcagcca gcgcaccggt tgttgaaaac gagccagctt
     7921 atctttcacc cattcgccaa gatcaacggt ttgctggtca tactccacca ccgctaccgg
     7981 ccgatgacca aactccttgt cggcaacggg aacgataaac acctgcaaaa ccgcaggatg
     8041 tgcagcaata acacgctcga cttcttccgg ctgaataccc tcaccgccac tgaagaacag
     8101 attgtctaaa cgtccgacaa tggtcagctt gccattatgc atctcaccgc gatcgcgcgt
     8161 agcgtaccag ccttcgtcat taaccagtga aaccagttgc ccgttacgcc agtaaccttc
     8221 tgccatactg gcagcccgca gccacacttc attattaacg attttcactt cccgacccgg
     8281 cagcggcgaa ccaacgtctg ccaggccgtc ggcttctttc gcacacaccg tggaggcaaa
     8341 ctcggtcaga ccatagccgc aaaagcaacg aatcccctgc tcgcgcgcct gttccgtcaa
     8401 ctcgaccggg atagccgcgc cgccaagtaa caccgctttc agggaaacgg aactgcggtt
     8461 aaccagcaaa cgccagagtt gtgttggcac cagtgaagcg tgagtacagc ctgccagcat
     8521 ttgctccaat ggctgtttat cacgcaccgt catccgcgca ccagcgtata accagcgcca
     8581 cataattccc tgaccggaga cgtgaaacag cggtaaagag agcaaccagt catcgtgatc
     8641 gccaaacgga atcaacgata acaccccttc ggcactggca agatgggcct gataagtatg
     8701 gacagcggct ttcggcaacc cggtagaacc cgaggtcaac gtcattgagc acagacgcgt
     8761 cggctgccac gtagcggcat gtgcgccttc aacccgctga atgtgcagcg acgttaacgc
     8821 cggaaacgtg ttttccccat ccggcaccag cgcaaattgc agcgtcagat tgggcagcaa
     8881 ttcttcaagc aacggttgcg gcagctgagg gttcacgggc aacacccgcg ccccgcattg
     8941 cagtaacgcc agccaggcga gcagcgtttg cggcgtattc cacgcccgca acatcacgcc
     9001 gctgccctca acaacgccct gcgccgcaaa gcctgaggct aattcatcga cgcgagcaca
     9061 aagctcgcgc cagttaagtt gctcgtcatt aagacgtaag gcgatggctt ctccccgcac
     9121 ttgccgccag tgacgccacg gccagtcaga gaagatcata acaaccgctc cagtgcatca
     9181 acttccacga caggcagcgt gctacccggc cagcgacgta cctgctgcgc ctgcatcaga
     9241 tccagcgtgt ccagccctgg aatggtgtcc ggcgttaacc aggcggcaat ccgcgccagt
     9301 tgcgttaagc ctaagctcga ttcaatggaa gaactgatca ccgccgtcag ccccagcgcg
     9361 tgcgccgcct gtacctgctc gcgtactttc tccagactgc ccgtgagcgt gggtttgata
     9421 actaccgcgc gcacgccctc ttcagccaca aaggcaaaat ccggctcgcg caggctttca
     9481 tcccaggcaa tggcaatgcc ggtttcacgg gcaaacgctc gcgaatcatc gcgggttttg
     9541 cacggctctt cgagaaacgc gatgcggtgg cgataatccg ggttaacata tttggcaaac
     9601 tgctggcctt tcagcggtgt ccaggcgcga tttgcgtcaa gacgcaaatg cagatccgga
     9661 attgcctcca gcaacagatt aaccaccatg ccgtcgcgca cggcttcgta caatcccact
     9721 ttgaccttcg ccactttctc gcctggcata tcagcaagtt tgaggatcag atcgtcagga
     9781 tcgccattac acagtggtgc cgcacggtaa ttggccgcct gcgggagcgt atctgccagc
     9841 tccgccaatg cacagcttac gccaaaggca acggaaggca tctgcggtag ctcgcaatcg
     9901 cctgccagcc agttatttac ccaggcaagc agcacgcttt gcgcctcttc ccaggtttcc
     9961 tggctgaagc ccggcagtgg ggagatctcc ccccaccctt cgcgctcgcc ctcacgcagg
    10021 caaacgtaca gcccgtcgcg ggtttttaac cgcctgtcgc gcagaaccac ccccgcgtcc
    10081 atggggatct gccagcggta tacctgcgcg ctacgcatta cggattccgt ttaaatttgc
    10141 tgaaatcagg ctgacgtttc tggttgaaag cgttgcgacc ttcctgacct tcttccgtca
    10201 tgtagaacag catggtggcg ttgcccgcca gctcctgcag ccccgcctgc ccgtcacagt
    10261 cggcgttcag cgcagctttc aggcagcgca gcgccatcgg gctgttttgc agcatttcgc
    10321 ggcaccaacg gacggtttct ttttccagat ccgccagcgg taccacggtg ttgacaaggc
    10381 ccatatccag cgcctgtttt gcgtcgtact gacggcacag gaaccagatt tctcgcgctt
    10441 ttttctgccc gacgatacga gccatgtagg aagcgcccca gccgccgtcg aaggaaccga
    10501 ctttcgggcc agtctgaccg aagatggcat tatctgctgc gatagtcagg tcgcacatca
    10561 tgtgcagaac gtgaccaccg ccgatggagt agccagccac catcgcgaca accggtttcg
    10621 gacaggtacg gatctgacgc tggaagtcca gcacgttcaa gtgatgtacg ccggaatcat
    10681 ctttatagcc gccgtaatca ccacgcactt tctggtcacc accggagcag aacgctttat
    10741 cgcctgcgcc agtcagaatg atcacgccga tattgtcgtc ataacgcgca tctgccagtg
    10801 cctggatcat ctcttttacc gtcagaggac ggaaggcatt gcgcacctgc ggacgattaa
    10861 tggtgatttt tgcgataccg tcggtggatt tttcataacg aatgtcctcg aaaccttcgg
    10921 agcagtcgtg ccattcaacc ggtgcgtaaa gcattgcttc atcaggataa atcatattgt
    10981 gtcctttagt cagaaacgca agatctgcgc cagacttgcg ataacgccag cgggattttc
    11041 ccgatgcgcg ttatgtccgg cgcgaggaat gacatggcag tcggcagcca gttccgccgc
    11101 cagggcgcgg aatttgctgt cacgttcacc acataaataa taaaacgcaa atgtgcgggc
    11161 gctaaggtta gcacgtaaat caggctggac ggcgagagaa gtcgcctcca gcatggcggc
    11221 aagggttgcg ccattattgt tgctgcgcag cgccaccagc tcccggcgtt gatcgtcatt
    11281 gagcgaggca aaaacaggct gttgatacca gtcggcaaat accgccgtta acggttctgt
    11341 gcgaaaacgc tgcgcccatt ggcgatcgga acgctgacgt tccgcacgtt gttcagcatt
    11401 ttgcagcccc ggatgcccgc cttcgacaat aaccccacaa agccccgcca gcccctggca
    11461 agccgccatc atcgccaccc gtccgccaag cgagtacccc accagccaaa agtcaaggat
    11521 gttgtaacta accaaggttt tacgcagtaa gtcggtgaca tcatcaaatc catcgacgct
    11581 aatcgccgcc gaaccaccat gacctgggag atcaacatac aaccgtgagt agtcggcaaa
    11641 cgcctcgccc acttcttgcc attcgtggca atcgccggaa aaaccgtgca aaaacaccag
    11701 ccagggtaaa cctggttttc cgtgttttgc ctgcgcgtgc aggatcataa atggcttacc
    11761 tgcgccagaa gttgctggag cgtttgcgca ccatcggtgt cgttaaccac catttcaatc
    11821 accgtggtgg ttggcgtgcg ccaggcgtcg gcaaatgccg tttcaagttc ctgccagttt
    11881 tgcggacgat gatatttcag ctcgaacatc gcggcggcgt gctcaaaatg gacgttttgc
    11941 ggcatcagat agaaacgctc acgctcgctt tgcggcgttg gcaacagcga gaaaatttgc
    12001 ccgccgttgt tgttcaccac aattaatacc agcggcgcag aaacctgacg caataacgcc
    12061 agcgcgttga gatcgtaaag tgcggagaga tcgcccacaa tcgccagcgt cggtttgccg
    12121 cttgcccgct gaacgcctgc ggcggtcgaa agcagtccgt cgataccgct ggcccctcgg
    12181 ttgctgtaca ccgggtaacc tgccggaagt tgcgaaagcg catcaatcag acgtaccacc
    12241 aggctgttac caacaaacaa ttgcccctgt tcaggcagat agtcgcagat gcgatgcgcc
    12301 agttgcgctt cgccaaacgc atcacggcgg gcaataaccg cctgcattgc ctgttccgcc
    12361 aggcgcggga tttcaacgca ccagggctgg cgtttttctg ccggatgcag ctccagccag
    12421 tcggcaatat tggcaattaa gcgacgtccg cgatggtgtg ccggatcaag tcgcccttca
    12481 atgtcatcaa caatccagta ctcttctggt tcacagcttg cctgccattg caggagccgt
    12541 ttgcccgtca ggctgcttcc cagttgcacc acaatttgcg cctgctgcag ctcgctggtc
    12601 gctttggcat tgcctaacca aagatcggca cacggcagcg gctgcccggt ttgtgacagc
    12661 acatcgccaa tcagcggcca gccaagagtt tgcgcccaca gggcaacttt tttgccctct
    12721 tccgcactca tgcgcccggc aaccaccacg ccgcgctttt gtcgccagaa gaaccagtcg
    12781 cgctgttttt cactttccag acgaggcgct tcacgcagcc acggtttgtc gtcctgccac
    12841 cagtcaccca gacgctgttg ccagctaagc ccggtatcgt ccatttcgcc atacagcggt
    12901 tcagcaaacg ggcagttgat atggactccc cccgcatgaa gcgtaccgag agcgtggtcg
    12961 atggtagaaa ccagccaacg tgcggggata tcccgggtcg ggcgcggcaa tgaaatactg
    13021 tgcgtggggt gagaggcgaa cattcccggc tggcgaattg cctgattcgc gccgcagtca
    13081 attagctccg gcgggcgatc ggcggttaac aggatcagtt tttctccggt taacccagct
    13141 tcaatcagtg ccggatagag atttgctacc gccgtgccgg aggtcacaat caccgccacc
    13201 ggctgcttgc tgactttcgc cagccccagc gccagatgtc ccagtccacg ctcatcgaaa
    13261 tgggtgtggt gaatgaatgt ggaattctcc gccgccgcta acgttaacgg tgtagaacgc
    13321 gagccagggg cgatacagat gtgtctgacg ccgtgacgcg ttaatgcttc cagaatgacc
    13381 gccgcccagc gtcggttaaa tgcgcttact gacatgagtt tgtccggtat caatattgcg
    13441 gctaagtata aggagctaca aaaatagatt attgatatga atcggtaatg atgcgactca
    13501 ttactattcc atctgtaata aagtacgcag ccctgccgct ttgttgtcga tttcctgcca
    13561 ctcttgctcg gggtcggaac cacggacaat gcccgcgcca gcatataatc gcacgacatt
    13621 gccgctaatt tttgctgagc gcagggaaac gcagaattcg ctttgttgta atgagagata
    13681 gcccgcagaa ccggcgtacc attctcgggt gaacggttcg tgacgggcga taaactgtcg
    13741 cgccagatcg cgcggtaagc cagcaactgc tgccgttggc tgcaactgat gtaaacagat
    13801 cacatcatcc gctttgttga gtgaagtcca gatacagcgg cgaagatgct gcactttacg
    13861 cagacgcagt acctgcggcg gtaaaacatc cagcgtctgg gtatcggcct gtaatcgttg
    13921 gcagatatct tccaccacca gcatgttctc gcgctggttt ttatcatccg ccatcagcca
    13981 ctctcctaac tgctgcgcct gcttatcatc aggattattt gctactgttc ccgccagcgc
    14041 ttcagtacgc agcgctttgt cacgccgccg ccataaccgt tccggtgaag agccaagaaa
    14101 agcattttcg ccatcaaagg ccatgtaaaa atggtagcaa ttcagattca gtcgacgact
    14161 ggcagccatc atcgccgccg cgttgaccgg acttgcgaaa tgcaggtcag ttgcccgagc
    14221 gagcaccact ttgtcgagct caccttcggc gatggttttc gttgccagtt cgattaattg
    14281 cgtccagccc gttttgtccg gccagtgttg ttctcgcgtg gtggttaaat gtaacccagg
    14341 caagggcttg atactcacca gtgtggcgat aaattctttt gcctgaatcg catcgtgctg
    14401 aagggagctt tcgctgaata gcgtcagccg cagcgtggct ttaccgccac agcgtcgcca
    14461 ttccaggcgg ggtaaaagta aattgccctg cgacgggtca aaagcattca gcccccaaat
    14521 gcgtaagtcg gcgtgttccg ggtgctggcg aagaaaacgt tgtgcctggt ccaacgacgt
    14581 aaaacgggta atcgcgccca ggacggcagc ttcttcatca ccattacgtt gttgccagta
    14641 gaattgcggg tacgtttgct gactggccag ccagctcaag gcatcaaaag cgtctttgag
    14701 agggaaagga atatcgataa cccgaatgcc gggtgtcgcc ggaatctctt gcgacaaatg
    14761 gcgcagtaga ttttccagcg ccgtagtaag tgattgcacg cggacctctc cctgttaaaa
    14821 gcctcacatt atacggggta ctacaaaaaa aatgcagtac cccggtgtag ggaggtttta
    14881 acggcgtgcc agcaacagtc ctagtaccag cccaacggcc gcgcccacac caattccttg
    14941 ccagggtttt tcgtggacgt agtcatcagc acgataaact gcctgcttcg cccgatagta
    15001 ataactgtct gaagcctggc taacccgttt tttcacatca tccagcgctt tttctgcacg
    15061 cgctttcagc tcaacatatt tctgatcggc gggatcgcca gaggagcgga gcacctcttc
    15121 cagtgtttca ctaagcagcg tcaggtcgtc atcgatacgt gtatcaccaa actgattaga
    15181 cattctcgtt ctccatttgc gtaaaacctg tcactaacta tagacaaggg ttgttgatta
    15241 cgcctgaatt acctcgcgtg ccatcccaat gtgtgggata ccatcttctt catagacctc
    15301 cgtcacaggg ataaaaccga aactctggta gaagttttgc agatgcgcct gcgccccgag
    15361 gtaaacaggc ttatcaggcc agtgatgcgt acatgtttcg agtgttttac tcatcagctg
    15421 ctgccccact ttttcgccac gcaacgcttc actgacaatc acccgaccta taacgaccgg
    15481 ctcaagatca tcatcacttt tcagaatcct cgcatacgcc accagttcat catttttcca
    15541 accgagaata tggcgattat cccccgtcaa atcatcacca tcgatatcct gataagggca
    15601 attctgctcg acaacaaaca ccgcgcaacg cagttgtaat aaggcataaa gctgggaaac
    15661 cgataattca gagtgatgca gatcttgcca ttcaatcata atgctctcct tttagatgta
    15721 tgccttatac tagccggaat attttttgaa acgtgatgaa ctcatggaat taattttttt
    15781 aggtacttca gccggtgtgc caacccgcac gcgcaatgtc acggcaatat tgcttaacct
    15841 gcaacatccg acccagagcg gactttggtt gtttgactgc ggtgaaggca cccagcatca
    15901 gctactgcat accgccttta accctggaaa actggacaag atttttatca gtcaccttca
    15961 tggcgatcat ctttttggtt tacccggctt gctgtgcagt cgttctatgt caggcattat
    16021 ccaaccctta acgatttatg gtccgcaagg tatccgtgaa tttgtggaaa ccgcgctgcg
    16081 gattagcggc tcatggaccg attatccgct ggaaattgtc gaaattggcg ctggcgaaat
    16141 tctcgatgat ggcctgcgca aagtaaccgc ttatccgctg gaacacccac tggaatgtta
    16201 tggctatcgt attgaagaac atgataaacc gggtgcatta aatgcccagg cattaaaagc
    16261 tgctggcgtg ccgcctggcc cactgtttca ggaattaaaa gcgggcaaaa caatcacgct
    16321 ggaagatgga aggcagatta acggcgcaga ttacttagct gctccagtgc caggtaaagc
    16381 gctcgctatt ttcggcgata ccggcccctg cgatgccgca cttgacctgg ctaaaggtgt
    16441 cgatgtcatg gtgcacgaag cgacgctgga tataaccatg gaagccaaag ccaatagtcg
    16501 cggccatagc tctacacgcc aggctgcgac actagcccgt gaggctggag tcggtaagct
    16561 aatcattacc cacgtcagct cgcgctatga tgacaaaggt tgtcagcacc tgttacgtga
    16621 atgcaggtca attttcccgg cgactgaact agcgaatgat ttcaccgtgt ttaacgttta
    16681 actctgctta ttattaaaaa cagggcgaaa cttgccctgt tatcgcaacc cgcgctacat
    16741 atatccaccc acacgggcat attgagcgat ttttgatatt tattcatctc ctcacgcact
    16801 atattcagag caataagttg cctctattta tcttgattca gcacaacctt tgcaactaaa
    16861 aggagcccat gatggttaca gttgtcagca attattgtca attatctcaa acgcaactca
    16921 gtcagacatt tgcagaaaaa tttactgtga ccgaggaatt actgcagtct ttaaaaaaaa
    16981 cagcgttatc cggagatgaa gaaagcattg agttactgca taatattgcg ttaggctatg
    17041 atgaatttgg aaaaaaagct gaagatattc tttaccatat tgttagaaac ccaacaaatg
    17101 agaccctatc gattatccga cttatcaaaa atgcttgttt aaaattatat aatttggcac
    17161 atgccgcaac caactccccc cttaaaccag ctggtccgga taattcagag gatctcctgt
    17221 tcaaaaagct attctcccct tcgaaattaa tgacaattat cggtgatgaa attcctctta
    17281 tatctgaaaa acagtcgctt tcgaaggtgc ttttaaatga tgagaataat gaactgagtg
    17341 atggtacaaa cttctgggat aaaaatcgtc aattaaccac agatgaaata gattgctatc
    17401 ttcagaagat cgccgctaat gcaaaaatac tgaagtcaat tatcctactg gtctctacgt
    17461 cccctactcc accagaactc acctggaaga cgctctcaat gaaaatatta agagcgatcc
    17521 atcatggccg aaagcagtcc agttattccc cataaatact ggcggacact ggatattagt
    17581 ttcgctacag aaaatagtaa atgaaaaaaa taatacacaa caaataaaat gcgtcatatt
    17641 caactcattg cgcgcactag gccatgataa agaaaattca cttaagcgtg
//
LOCUS       DAPGUL010000091        17647 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.092, whole genome shotgun sequence.
ACCESSION   DAPGUL010000091 DAPGUL010000000
VERSION     DAPGUL010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17647
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.092"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            212..1264
                     /locus_tag="RHX21_003315"
     CDS             212..1264
                     /locus_tag="RHX21_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2776 domain-containing protein"
                     /protein_id="HDV1988461.1"
                     /translation="MNIYIGWLFKLIPLIMGLICIALGGFVLESSGQSEYFVAGHVLI
                     SLAAICLALFTTAFIIISQLTRGVNTFYNTLFPIIGYAGSIITMIWGWALLAGNDVMA
                     DEFVAGHVIFGVGMIAACVSTVAASSGHFLLIPKNAAGSKSDGTPVQAYSSLIGNCLI
                     AVPVLLTLLGFIWSITLLRSADITPHYVAGHVLLGLTAICACLIGLVATIVHQTRNTF
                     STKEHWLWCYWVIFLGSITVLQGIYVLVSSDASARLAPGIILICLGMICYSIFSKVWL
                     LALVWRRTCSLANRIPMIPVFTCLFCLFLASFLAEMAQTDMGYFIPSRVLVGLGAVCF
                     TLFSIVSILEAGSAKK"
     gene            complement(1580..2782)
                     /locus_tag="RHX21_003316"
     CDS             complement(1580..2782)
                     /locus_tag="RHX21_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDV1988462.1"
                     /translation="MERFDAIIIGAGAAGMFCSALAGQAGRRVLLIDNGKKPGRKILM
                     SGGGRCNFTNLYVEPGAYLSQNPHFCKSALARFTQWDFIDLVNKHGIAWHEKTLGQLF
                     CDDSAQQIVDMLVDECEKGNVTFRLRSEVLSVAKDETGFTLELNGMTVGCEKLVIATG
                     GLSMPGLGASPFGYKIAEQFGLNVLPTRAGLVPFTLHKPLLEELQVLAGVAVPSVITA
                     ENGIVFRENLLFTHRGLSGPAVLQISSYWQPGEFVSINLLPDVDLETFLNEQRNAHPN
                     QSLKNTLAVHLPKRLVERLQQLGQIPDVSLKQLNVRDQQALISTLTDWRVQPNGTEGY
                     RTAEVTLGGVDTNELSSRTMEARKVPGLYFIGEVMDVTGWLGGYNFQWAWSSAWACAQ
                     DLIAAKSS"
     gene            3014..4513
                     /gene="pitA"
                     /locus_tag="RHX21_003317"
     CDS             3014..4513
                     /gene="pitA"
                     /locus_tag="RHX21_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter PitA"
                     /protein_id="HDV1988463.1"
                     /translation="MLHLFAGLDLHTGLLLLLALAFVLFYEAINGFHDTANAVATVIY
                     TRAMRSQLAVVMAAVFNFLGVLLGGLSVAYAIVHMLPTDLLLNMGSSHGLAMVFSMLL
                     AAIIWNLGTWYFGLPASSSHTLIGAIIGIGLTNALMTGTSVVDALNIPKVLSIFGSLI
                     VSPIVGLVFAGGLIFLLRRYWSGTKKRARIHLTPAEREKKDGKKKPPFWTRIALILSA
                     IGVAFSHGANDGQKGIGLVMLVLIGVAPAGFVVNMNATGYEITRTRDAINNVEAYFEQ
                     HPALLKQATGADQLVPAPEAGATQPAEFHCHPSNTINALNRLKGMLTTDVESYDKLSL
                     DQRSQMRRIMLCVSDTIDKVVKMPGVSADDQRLLKKLKSDMLSTIEYAPVWIIMAVAL
                     ALGIGTMIGWRRVATTIGEKIGKKGMTYAQGMSAQMTAAVSIGLASYTGMPVSTTHVL
                     SSSVAGTMVVDGGGLQRKTVTSILMAWVFTLPAAVLLSGGLYWLSLQFL"
     gene            complement(4584..4919)
                     /gene="uspB"
                     /locus_tag="RHX21_003318"
     CDS             complement(4584..4919)
                     /gene="uspB"
                     /locus_tag="RHX21_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspB"
                     /protein_id="HDV1988464.1"
                     /translation="MISTVALFWALCVVCIVNMARYFSSLRALLVVLRNCDPLLYQYV
                     DGGGFFTSHGQPNKQVRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCGLVVV
                     SLIALMIWH"
     gene            5310..5744
                     /gene="uspA"
                     /locus_tag="RHX21_003319"
     CDS             5310..5744
                     /gene="uspA"
                     /locus_tag="RHX21_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspA"
                     /protein_id="HDV1988465.1"
                     /translation="MAYKHILIAVDLSPESKVLVEKAVSMARPYNAKVSLIHVDVNYS
                     DLYTGLIDVNLGDMQKRISEETHHALTELSTNAGYPITETLSGSGDLGQVLVDAIKKY
                     DMDLVVCGHHQDFWSKLMSSARQLINTVHVDMLIVPLRDEEE"
     gene            6062..7531
                     /gene="dtpB"
                     /locus_tag="RHX21_003320"
     CDS             6062..7531
                     /gene="dtpB"
                     /locus_tag="RHX21_003320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpB"
                     /protein_id="HDV1988466.1"
                     /translation="MNTTTPMGMLQQPRPFFMIFFVELWERFGYYGVQGVLAVFFVKQ
                     LGFSQEQAFVTFGAFAALVYGLISIGGYVGDHLLGTKRTIVLGALVLAIGYFMTGMSL
                     LKPDLIFIALGTIAVGNGLFKANPASLLSKCYPPKDPRLDGAFTLFYMSINIGSLIAL
                     SLAPVIADRFGYSVTYNLCGAGLIIALLVYIACRGMVKDIGSEPDFKPMSFSKLLYVL
                     LGSVVMIFVCAWLMHNVEVANLVLIVLSIVVTIIFFRQAFKLDKTGRNKMFVAFVLML
                     EAVVFYILYAQMPTSLNFFAINNVHHEILGFSINPVSFQALNPFWVVLASPILAGIYT
                     HLGNKGKDLSMPMKFTLGMFMCSLGFLTAAAAGMWFADAQGLTSPWFIVLVYLFQSLG
                     ELFISALGLAMIAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPDNITDPLET
                     LPVYTNVFGKIGLVTLGVAVVMLLMVPWLKRMIATPESH"
     gene            complement(7580..8332)
                     /gene="rsmJ"
                     /locus_tag="RHX21_003321"
     CDS             complement(7580..8332)
                     /gene="rsmJ"
                     /locus_tag="RHX21_003321"
                     /EC_number="2.1.1.242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1516)-N(2))-methyltransferase
                     RsmJ"
                     /protein_id="HDV1988467.1"
                     /translation="MKICLIDETGTGDGALSVLAVRWGLEHDEDNLMALVLTPEHLEL
                     RKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRD
                     AFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALTD
                     ITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVK
                     RPDYAPPLANVATPNAVVTKGHRFDIYAGTPV"
     gene            complement(8340..10382)
                     /gene="prlC"
                     /locus_tag="RHX21_003322"
     CDS             complement(8340..10382)
                     /gene="prlC"
                     /locus_tag="RHX21_003322"
                     /EC_number="3.4.24.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020317218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptidase A"
                     /protein_id="HDV1988468.1"
                     /translation="MTNPLLTPFELPPFSKILPEHVVPAVTKALNDCRENVERVVAQG
                     APYTWENLCQPLAEVDDVLGRIFSPVSHLNSVKNSPELREAYEQTLPLLSEYSTWVGQ
                     HEGLYKAYRDLRDGDHYATLNTAQKKAVDNALRDFELSGIGLPIEKQQRYGEIATRLS
                     ELGNQYSNNVLDATMGWTKLVTDEAELAGMPESALAAAKAQAEAKELEGYLLTLDIPS
                     YLPVMTYCDNQALREEMYRAYSTRASDQGPNAGKWDNSKVMEEILALRHELAQLLGFE
                     NYAFKSLATKMAENPQQVLDFLTDLAKRARPQGEKELAQLRAFAKAEFGVDELQPWDI
                     AYYSEKQKQHLYSISDEQLRPYFPENKAVNGLFEVVKRIYGITAKERKDVDVWHPDVR
                     FFELYDENNELRGSFYLDLYARENKRGGAWMDDCVGQMRKADGSLQKPVAYLTCNFNR
                     PVNGKPALFTHDEVITLFHEFGHGLHHMLTRIETAGVSGISGVPWDAVELPSQFMENW
                     CWEPEALAFISGHYETGEPLPKELLDKMLAAKNYQAALFILRQLEFGLFDFRLHAEFR
                     PDQGAKILETLAEIKKLVAVVPSPSWGRFPHAFSHIFAGGYAAGYYSYLWADVLAADA
                     FSRFEEEGIFNRETGQSFLDNILSRGGSEEPMDLFKRFRGREPQLDAMLEHYGIKG"
     gene            10585..11427
                     /gene="rlmJ"
                     /locus_tag="RHX21_003323"
     CDS             10585..11427
                     /gene="rlmJ"
                     /locus_tag="RHX21_003323"
                     /EC_number="2.1.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2030)-N(6))-methyltransferase"
                     /protein_id="HDV1988469.1"
                     /translation="MLSYRHSFHAGNHADVLKHTVQSLIIESLKEKDKPFLYLDTHAG
                     AGRYQLGSEHAERTGEYLEGIARIWQQDDLPAELEAYINVVKHFNRSGQLRYYPGSPL
                     IARQLLREQDSLQLTELHPSDYPLLRSEFQKDSRARVEKADGFQQLKAKLPPVSRRGL
                     ILIDPPYEMKTDYQAVVSGIAEGYKRFATGTYALWYPVVLRQQIKRMIHDLEATGIRK
                     ILQIELAVLPDSDRRGMTASGMIVINPPWKLEQQMNNVLPWLHSKLVPAGTGHATVSW
                     IVPE"
     gene            11499..12851
                     /gene="gorA"
                     /locus_tag="RHX21_003324"
     CDS             11499..12851
                     /gene="gorA"
                     /locus_tag="RHX21_003324"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003861215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HDV1988470.1"
                     /translation="MTKHYDYIAIGGGSGGIASINRAAMYGQKCALIEAKELGGTCVN
                     VGCVPKKVMWHAAQIREAIHMYGPDYGFDTTINKFNWETLIASRTAYIDRIHTSYENV
                     LGKNNVDVIKGFARFVDAKTLEVNGETITADHILIATGGRPSHPDIPGVEYGIDSDGF
                     FALPALPERVAVVGAGYIAVELAGVINGLGAKTHLFVRKHAPLRSFDPMISETLVEVM
                     NAEGPQLHTNAIPKAVVKNADGSLTLELEDGRSETVDCLIWAIGREPANDNINLEAAG
                     VKTNEKGYIVVDKYQNTNIEGIYAVGDNTGAVELTPVAVAAGRRLSERLFNNKPDEHL
                     DYSNIPTVVFSHPPIGTVGLTEPQAREQYGDDQVKVYKSSFTAMYTAVTTHRQPCRMK
                     LVCVGSEEKIVGIHGIGFGMDEMLQGFAVALKMGATKKDFDNTVAIHPTAAEEFVTMR
                     "
     gene            complement(12905..12988)
                     /locus_tag="RHX21_003325"
     CDS             complement(12905..12988)
                     /locus_tag="RHX21_003325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165328.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Damage inducible protein"
                     /protein_id="HDV1988471.1"
                     /translation="MIDKAIIVLGALIALLELIRFLLQLLN"
     gene            13728..14081
                     /gene="arsR"
                     /locus_tag="RHX21_003326"
     CDS             13728..14081
                     /gene="arsR"
                     /locus_tag="RHX21_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="As(III)-sensing metalloregulatory
                     transcriptional repressor ArsR"
                     /protein_id="HDV1988472.1"
                     /translation="MSFLLPIQLFKILADETRLGIVLLLSELGELCVCDLCTALDQSQ
                     PKISRHLALLRESGLLLDRKQGKWVHYRLSPHIPAWAAKIIDEAWQCEQEKVQAIVRN
                     LARQNCSGDSKNICS"
     gene            14135..15424
                     /gene="arsB"
                     /locus_tag="RHX21_003327"
     CDS             14135..15424
                     /gene="arsB"
                     /locus_tag="RHX21_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenite/antimonite:H(+) antiporter ArsB"
                     /protein_id="HDV1988473.1"
                     /translation="MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPG
                     DIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAALHVSRWGNGRGRLLFTWIVLLG
                     AAVAALFANDGAALILTPIVIAMLLALGFSKGTTLAFVMAAGFIADTASLPLIVSNLV
                     NIVSADFFGLGFREYASVMVPVDIAAIVATLVMLHLYFRKDIPQNYDMALLKSPAEAI
                     KDPATFKTGWVVLLLLLVGFFVLEPLGIPVSAIAAVGALILFVVAKRGHAINTGKVLR
                     GAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAATLGTGFLTAFLSSI
                     MNNMPTVLVGALSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQ
                     KNMTISWGYYFRTGIIMTLPVLFVTLAALALRLSFTL"
     gene            15437..15862
                     /gene="arsC"
                     /locus_tag="RHX21_003328"
     CDS             15437..15862
                     /gene="arsC"
                     /locus_tag="RHX21_003328"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-dependent arsenate reductase"
                     /protein_id="HDV1988474.1"
                     /translation="MSNITIYHNPACGTSRNTLEMIRNSGTEPTIIYYLETPPTRDEL
                     VKLIADMGISVRALLRKNVEPYEELGLAEDKFTDDRLIDFMLQHPILINRPIVVTPLG
                     TRLCRPSEVVLEILPDAQKGAFSKEDGEKVVDEAGKRLK"
     gene            complement(15996..16292)
                     /locus_tag="RHX21_003329"
     CDS             complement(15996..16292)
                     /locus_tag="RHX21_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001465662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDV1988475.1"
                     /translation="MQLEEVAKALKELGHPTRLFIFKHLVKAGEQGLPVGELQKQLGI
                     PGSTLSHHISALVSVGLVKQNRESRTLMCVSQYAMLEAIIEFLREECCVNSKIA"
     gene            16399..17400
                     /locus_tag="RHX21_003330"
     CDS             16399..17400
                     /locus_tag="RHX21_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000100290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDV1988476.1"
                     /translation="MSSWLAMLQDAAEMFVFLAVELSLLFIVISAGVSLIRQKVPDHK
                     IQQMMGARKGRGYLLAALLGAVTPFCSCSTIPMLRGLLSAKAGFGPTLTFLFVSPLLN
                     PIIVGLMWMTFGWKVTLLYAIIAAGVSVLASIILDSLGFERHIIASKSSSANCCAPAK
                     TSPGTTYTPIKVSCCSPAAKAIENPVVTCCSTKAVVSINPIKLATKDALQQFKDVLPY
                     LLLGVLIGSFIYGFIPSAWIAAHAGADNPFAIPLSAVVGIPLYIRAEAVIPLASVLMT
                     KGMGLGALMALIIGSAGASLTEVILLKSMFRMPMIAAFLTVILGMAILMGYLTQLLF"
BASE COUNT         4088 a         4515 c         4442 g         4602 t
ORIGIN      
        1 gtaaaaaaaa caacagaata agaattaatc ttaggataaa tatttattta tcatggcctt
       61 ttaaccggta aaaaatggca ctcggcacag taaaccccgc tatagttatg ctatgcattt
      121 gtctttaatg atatctcgtc gttatattaa caggctgaaa ttatcattaa tgcacatttc
      181 attattagca gggatacctg aggagtttaa agtgaacata tatatcgggt ggcttttcaa
      241 attaatccct ttgattatgg gattaatttg catcgcgtta ggtggctttg tgctggaaag
      301 ttcagggcaa agcgagtatt tcgtcgcggg tcatgtgctg atttctctgg cggccatatg
      361 cctggcatta ttcactaccg catttattat catttcgcag ctcacgcgcg gcgttaatac
      421 gttttacaat acattgttcc ccattattgg ctatgcgggg tcaattatca ccatgatatg
      481 gggttgggca ctgttagcag gcaatgatgt gatggcagac gagtttgtcg ccggccatgt
      541 tattttcggc gttggtatga ttgccgcctg tgtatcgacg gtggcagcgt catccggtca
      601 ctttctgctc attcccaaaa atgcagcggg gagcaagagc gatggaacgc cggtacaggc
      661 ttattcttca ttaatcggta attgcctcat tgccgttccc gttttactca ccctgctcgg
      721 tttcatttgg tctattacgc tgttacgtag tgctgacata actccgcatt atgtcgcggg
      781 tcacgtattg cttgggttaa ccgcaatctg tgcctgtcta attggccttg ttgccacaat
      841 tgtccatcaa acacgtaata cgttttcaac taaagaacac tggctgtggt gttattgggt
      901 tatttttctc ggctcaatca cggtactgca ggggatatac gtcttagtca gttccgatgc
      961 aagcgcccga ctggctcccg gcattattct tatttgcctc ggaatgatct gttacagcat
     1021 attctcaaaa gtctggctac tggcactggt atggagacgt acctgttcgt tagccaacag
     1081 aataccgatg attcccgtct tcacctgcct gttttgcctt ttcctggcat cgtttcttgc
     1141 ggaaatggcg cagaccgaca tgggatattt tattccttcg cgggttttgg tcggtttagg
     1201 agcggtatgc tttacgttgt tctcaatcgt ttcaatatta gaagcaggtt ctgctaaaaa
     1261 ataattgcaa cgtaccggat aaaaccagcg ttgaccattt gcgtaacgct ggtttttctt
     1321 aggcatcatg aaataacgca gcattaatgc atagtggtta aggataaaaa aacaacaaag
     1381 ttactgtttt tttcaacctg ttcatatttt ataaagatct ggccactggg tgagttttca
     1441 atcacctttc cttccacctt atattaagcc tggagggttt cagttcacgg gctcattaga
     1501 aaataatcac aagatagcca ctatcaaaat tagctcattt ttaatgcggc tctaataatt
     1561 ttcatcttta ggtaacaggt caggacgact tcgctgcaat caaatcctgc gcacaagccc
     1621 acgcactcga ccacgcccac tggaagttat agccccccag ccagccggta acgtccatca
     1681 cttcgccgat gaagtacagc ccaggcactt tgcgcgcttc catcgtccgt gaagagagtt
     1741 cgttggtgtc cacgccgccg agcgtcactt cggcagtgcg atagccttca gtgccgttgg
     1801 gttgtacgcg ccagtcggtc aatgtgctaa tcagtgcctg ttggtcacgc acgttgagct
     1861 gttttagcga aacatccggg atttgcccga gttgctgtaa gcgttcaacc aaccgcttcg
     1921 gtagatgaac cgccagtgtg tttttcaggc tctgattcgg atgtgcgtta cgctgctcat
     1981 tcaggaaggt ttcgagatcc acatccggta gcagattgat actgacaaat tcacccggtt
     2041 gccagtagct ggaaatctgc aacaccgccg gtccagacaa gccgcgatgg gtgaagagta
     2101 agttctcacg gaaaacgatg ccgttttcag cggtaatcac ggaaggcacc gccacgcccg
     2161 ccagcacctg taactcttcg agcaacggtt tatgcagagt gaatggcacc agacccgcgc
     2221 gggtcggcag cacgttgagg ccaaattgtt cggcaatctt ataaccaaac ggcgacgcgc
     2281 ccagccccgg cattgacagc ccaccggtcg cgatgaccag cttttcgcaa ccgacagtca
     2341 tgccgttcag ttcaagcgtg aagcctgttt catccttcgc cacactcagc acttcgctac
     2401 gcaatctgaa ggttacattg cccttctcgc actcatccac cagcatgtcg acaatctgct
     2461 gcgcggagtc atcgcagaag agttgtccta acgttttctc gtgccaggcg atgccgtgtt
     2521 tattgaccag atcaatgaaa tcccactggg taaaacgcgc gagtgcagac ttacaaaaat
     2581 gcggattctg gctcagataa gcgcctggtt cgacataaag gttggtaaag ttgcagcgcc
     2641 caccgccaga cataaggatt ttgcgccctg gttttttacc attatcgatc agcagaaccc
     2701 ggcgtcctgc ctgacctgcc agcgcagaac agaacatacc cgccgcacca gcgcctataa
     2761 taatggcatc aaacctttcc acgttgcgct cctcttagaa aaaacgggcg tgaattgtaa
     2821 agattcctca gtggtcgcac cagcatcaat attactaaaa ggaagtattt gcctgaatta
     2881 tataagataa ttattttttg agtgaaatcc atacaggagg caaatcaaaa aaagtctata
     2941 tttcactttg cccgcgccgc gaaagtcact gataatgcgc cgcgttcatg tcctcaaaat
     3001 ggcgtaacgt cctatgctac atttgtttgc tggcctggat ttgcataccg ggctgttatt
     3061 attgcttgca ctggcttttg tgctgttcta cgaagccatc aatggtttcc atgacacagc
     3121 caacgccgtg gcaaccgtta tctatacccg cgcgatgcgt tctcagctcg ccgtggttat
     3181 ggcggcggtg ttcaactttt tgggtgtttt gctgggtggt ctgagtgttg cctatgccat
     3241 tgtgcatatg ctgccgacgg atctgctgct taatatggga tcgtctcatg gccttgccat
     3301 ggtgttctct atgttgctgg cggcgattat ctggaacctg ggtacctggt actttggttt
     3361 acctgcatcc agctctcata cgctgattgg cgcgatcatc gggattggtt taaccaatgc
     3421 gttgatgacc gggacgtcag tggtggatgc actcaatatc ccgaaagtat taagtatttt
     3481 cggttctctg atcgtttccc ctattgtcgg cctggtgttt gctggcggtc tgattttctt
     3541 gctgcgtcgc tactggagcg gcaccaagaa acgcgcccgt atccacctga ccccagcgga
     3601 gcgtgaaaag aaagacggca agaaaaagcc gccgttctgg acgcgtatcg cgctgatcct
     3661 ttccgctatc ggcgtggcgt tttcgcacgg cgcgaacgat ggtcagaaag gcattggtct
     3721 ggttatgttg gtattgattg gcgtcgcgcc agcaggcttc gtggtgaaca tgaatgccac
     3781 tggctacgaa atcacccgta cccgtgatgc catcaacaac gtcgaagctt actttgagca
     3841 gcatcctgcg ctgctcaaac aggctaccgg tgctgatcag ttagtaccgg ctccggaagc
     3901 tggcgcaacg caacctgcgg agttccactg ccatccgtcg aataccatta acgcgctcaa
     3961 ccgcctgaaa ggtatgttga ccaccgatgt ggaaagctac gacaagctgt cgcttgatca
     4021 acgtagccag atgcgccgca ttatgctgtg cgtttctgac actatcgaca aagtggtgaa
     4081 gatgcctggc gtgagtgctg acgatcagcg cctgttgaag aaactgaagt ctgacatgct
     4141 tagcaccatc gagtatgcac cggtgtggat catcatggcg gtcgcgctgg cgttaggtat
     4201 cggtacgatg attggctggc gccgtgtggc aacgactatc ggtgagaaaa tcggtaagaa
     4261 aggcatgacc tacgctcagg ggatgtctgc ccagatgacg gcggcagtgt ctatcggcct
     4321 ggcgagttat accgggatgc cggtttccac tactcacgta ctctcctctt ctgtcgcggg
     4381 gacgatggtg gtagatggtg gcggcttaca gcgtaaaacc gtgaccagca ttctgatggc
     4441 ctgggtgttt acccttccgg ctgcggtact gctttccggc gggctgtact ggctctcctt
     4501 gcagttcctg taatcgtaca caccaaaacg agcgggtcag tttactggcc cgcttttttt
     4561 atgcgttatt attgctgaag tgcttaatgc caaatcatca atgcaatcag gctgaccacc
     4621 accagaccac acaatgcgct ggtcagaata aactgccgac gcacccgctc acagcggcga
     4681 ataaattcat catcgtgatg atcgcgataa cgttgggcat agatatacca aacgagacgc
     4741 acctgtttgt tgggttggcc atgtgaggta aaaaagcccc ctccatcaac atattgatag
     4801 agcaatggat cgcagttacg cagtaccact aacaacgcgc gtagtgatga gaaatagcgc
     4861 gccatgttaa caatgcaaac gacacataaa gcccaaaata atgcgacggt gcttatcata
     4921 cctcctcccc ggcgacctgc ccgcggagtt ccaccccggg gctaccgctc ccgatacgct
     4981 gccaatcagt taacaccagg tcctggagaa accgcttttg tggtgaccaa catccgagcg
     5041 gctctataga tagtgtagga gatcaggttg ttttttttcc agaaggttaa ccactatcaa
     5101 tatattcatg tcgaaaattt gtttatctaa cgggtaagca aggcggattg acggatcatc
     5161 cgggtcgcta taaggtaagg atggtcttaa cactgaatct ttacggctgg gttagccccg
     5221 cgcacgtagt tcgcaggacg cgggtgacgt aacggcacaa gaaacgctag ctggccagtc
     5281 atcgacaact ttatggaagg agtaacacta tggcttataa acacattctc atcgcagtcg
     5341 atctctcccc ggaaagcaaa gttctggtag agaaagcagt ctctatggct cgcccctaca
     5401 atgcgaaagt ttctctgatc cacgtagatg taaactactc tgacctatac accgggctta
     5461 ttgatgtgaa tctgggtgat atgcagaaac gcatctctga agagacacat catgcgctga
     5521 ccgagctttc cactaatgca ggctacccaa tcactgaaac cctgagcggc agcggcgacc
     5581 tgggccaggt tctggtcgat gcaatcaaga aatacgatat ggatctggtg gtttgtggtc
     5641 accaccagga cttctggagc aaactgatgt cttccgcacg tcagctgatc aacaccgttc
     5701 acgttgatat gctgattgtt ccgctgcgcg acgaagaaga ataatcatcc ctccacgacg
     5761 tgttcctgaa cgcccgcata tgcgggcgtt ttgctttttg gcgcgccttg ttacctgatg
     5821 cagcgtaaac cccttatctg gcctacgatc tgcgtacgca atcaaaatct cctgccaata
     5881 caacatttaa caccatcata ttttccatca ttagtgtgat cagctggtta ttttctgttg
     5941 taatagtgta ttaatctatt caccgcatca atattaagaa tctctgacag atgtaaactt
     6001 tttcgcgcgt tatcccttac gcgttcatac ttttcaggat ggtattggaa ggttaataaa
     6061 tatgaataca acaacaccca tggggatgct gcagcaacct cgcccatttt tcatgatctt
     6121 ttttgtcgag ttatgggagc gattcggcta ctacggcgtg cagggcgtac tggcggtttt
     6181 cttcgttaaa cagcttggat tctcgcaaga gcaggctttt gtcacttttg gtgcttttgc
     6241 tgcgctggtc tatggcctca tttccattgg cggctatgtc ggcgaccacc tgctggggac
     6301 caaacgcacc attgttctcg gagcacttgt gctggcgatt ggctacttca tgaccggcat
     6361 gtcgctactt aagcctgacc tgattttcat cgccctgggg actatcgctg tcggtaacgg
     6421 cctgtttaaa gctaacccag ccagcttgct ttcgaagtgc tatccgccga aagatccgcg
     6481 gcttgatggc gcattcaccc tgttctatat gtcgatcaat atcggctcgt tgatagcgtt
     6541 atcgctggcc cctgtgatcg ctgatagatt cggttattca gtcacctaca acctgtgcgg
     6601 ggcggggtta attatcgcat tactggttta catcgcctgt cgtggaatgg tgaaagacat
     6661 tggttctgaa cccgacttca agccgatgag cttcagcaaa ctgttgtacg tattacttgg
     6721 cagcgtggtg atgatcttcg tatgtgcatg gctgatgcac aacgtagaag tcgccaatct
     6781 ggtgctgatt gttctctcca tcgtcgtcac catcatcttc tttcgtcagg cattcaagct
     6841 ggataaaacc gggcgcaata aaatgtttgt cgcctttgtc ctgatgctcg aagcggtggt
     6901 gttttacatt ctctacgccc agatgccaac atcgctgaac ttctttgcca tcaacaacgt
     6961 gcatcatgaa attctcggtt tttccatcaa cccggtcagc ttccaggcgc ttaacccgtt
     7021 ctgggtggta ctcgccagcc caatactggc aggcatttac acgcatctgg gtaacaaagg
     7081 caaagacctc tcgatgccga tgaaatttac tctcggcatg tttatgtgct ctctgggctt
     7141 tttgacggct gcagctgcgg gaatgtggtt tgcggatgcc caggggctga catcgccatg
     7201 gtttatcgtg ctggtgtact tattccagag cttaggtgaa ctgtttatta gcgcccttgg
     7261 cctggcgatg attgctgccc tggtgccgca gcatttgatg ggctttattc tcgggatgtg
     7321 gttcctgacg caggctgccg cgttcttgct gggcggctat gtggcaacat ttaccgcggt
     7381 gccggacaac attaccgatc cgcttgagac gttgcccgtc tataccaacg tgtttggtaa
     7441 gattggtctg gtcacactgg gcgttgcagt agtgatgctg ttgatggtgc cgtggctgaa
     7501 acgcatgatt gcgacgccgg aaagccatta attattcttg cagaaagcag ggtagcgtta
     7561 tcgctaccct ggtttacttt tacactggcg tacctgcata aatatcaaac ctatgccctt
     7621 tagtgactac cgcgtttggc gtggcgacat tcgccagcgg tggcgcgtag tccgggcgct
     7681 ttaccaccac gcgtttggtc gccagcaagc gtgcaggctc cagtaatcca tcggcatcaa
     7741 gatccggtcc caccagcgac tgaaagacac gcatctcttt tttcactagc gcgcttttct
     7801 gcttatgcgg gaacatcggg tcgagataaa ccacctgcgg gcgcggggta atatcagtca
     7861 gcgccgtcag gctggaggcg tgaattaact gcaaccgctc ctgcaaccag ccgccgattt
     7921 ccgcatccgc ataaccacgc gccaggccgt cgtcgagcaa tgcggcaacg actggattac
     7981 gctccagcat ccgcacgcgg cagccgactg aagccagcac aaaggcatcg cgccccagcc
     8041 ctgcggtggc atccaccaca tccggcaaat aatcgccttt aatgcccacc gctttcgcca
     8101 ccgcctcacc gcgaccaccg ccgaatttgc gtcggtgcgc catcgctccg ccaacaaaat
     8161 caacaaagat gccgccaagt tttggctcat cacgcttgcg caattccaga tgttccggcg
     8221 ttaacaccag cgccatcagg ttgtcttcat cgtgctccag cccccagcgg accgccagaa
     8281 cagataaggc accgtctccg gtgcctgttt catcaattaa gcagattttc actgaatgat
     8341 cagcccttaa tgccgtaatg ctccagcatc gcatccagct gcggttcacg accacggaag
     8401 cgtttgaaca gatccatcgg ctcttctgaa ccgccacggc tcagaatgtt gtcgaggaac
     8461 gactgcccgg tttcacggtt gaaaatgccc tcttcctcaa agcgcgagaa agcatctgcc
     8521 gccagtacgt cagcccacag gtagctgtag taacctgcgg cataaccacc ggcgaaaata
     8581 tggctgaaag cgtgcgggaa acggccccag gatggagacg gtactacggc aaccagtttc
     8641 ttgatttctg ccagagtttc gaggattttc gctccctgat ccgggcggaa ctcggcatgg
     8701 aggcggaaat cgaacaggcc gaactccagc tggcgcagaa taaacagcgc cgcctggtag
     8761 ttcttcgccg ccagcatttt atccagcaac tctttcggca gcggttcgcc ggtttcgtag
     8821 tgaccggaga taaacgccag cgcctccggc tcccagcacc agttttccat aaactgactc
     8881 ggcagttcga ccgcatccca cggcacaccg ctgataccgg aaacaccagc ggtttcgatg
     8941 cgggtcagca tatggtgcag gccgtgaccg aactcgtgga acagggtgat cacttcgtcg
     9001 tgagtgaaca gcgccggttt accatttacc gggcggttga agttacaagt caaatacgcg
     9061 accggttttt gcagcgaacc atcagcttta cgcatctggc ctacgcagtc atccatccac
     9121 gccccgccgc gcttgttttc acgggcatac agatcgaggt agaagctgcc gcgcagttcg
     9181 ttattttcgt catacagttc gaagaaacgt acatccggat gccagacatc aacatcttta
     9241 cgctctttag cggtgatgcc gtaaatacgt ttcaccactt caaacaggcc gttaaccgct
     9301 ttgttttctg ggaagtacgg acgcagctgc tcgtcgctga tgctgtagag gtgctgtttt
     9361 tgtttttcgc tgtagtacgc gatatcccac ggctgcaact catcgacgcc aaattccgct
     9421 ttggcgaagg cgcgcagttg tgccagctct ttttcgcctt gcggacgcgc gcgttttgcc
     9481 agatcggtta agaaatccag cacctgctgc gggttttctg ccattttagt ggcaagggat
     9541 ttaaaggcgt agttttcaaa gcccagcagt tgcgccagtt cgtgacgcag agcgaggatc
     9601 tcttccatca ccttgctgtt atcccattta ccggcgttcg ggccttgatc ggaggcgcgg
     9661 gtgctgtaag cgcgatacat ctcttcacgc aaggcctggt tgtcgcagta ggtcattacc
     9721 ggcaggtagc ttgggatatc cagcgtcagc aggtagcctt ccagctcttt cgcttcggcc
     9781 tgggcttttg ccgcagccag cgcgctttca ggcatccccg ccagctccgc ttcgtcggta
     9841 acgagtttgg tccagcccat cgtcgcatcg aggacgttgt tgctgtactg gttgcccagc
     9901 tcggaaagac gagtggcaat ctcaccgtag cgttgttgtt tctctattgg cagaccgatg
     9961 ccagagagtt cgaagtcgcg cagtgcgtta tcaaccgctt ttttctgagc cgtgttcagc
    10021 gtggcgtaat gatcgccatc gcgcaggtcg cgatacgctt tatacagccc ttcatgttgc
    10081 cctacccagg tgctgtattc cgacagcagc ggcagggttt gttcgtacgc ttcacgcagt
    10141 tccgggctat ttttcaccga gttcaggtgg ctgaccgggg agaagatacg ccccagcaca
    10201 tcgtccactt ccgccaacgg ctggcagaga ttttcccagg tgtacggtgc tccttgcgct
    10261 actacgcgct ccacattttc gcggcagtcg ttcagcgcct tagtcacggc tggaacgaca
    10321 tgttccggga gaattttaga aaacggaggc aattcaaagg gagtcagtaa cggattcgtc
    10381 attcgcgcag tcctggttaa agaggttaag gaagcgctca acaggcgctt tacataatgt
    10441 gtgtagcatg gggttaagtg tagtgaattt caatgagaaa cgttacgctt tcgcggcggc
    10501 ggcctctttt cggtatactg tcctgatacg cttttgtgcg ccccgaatac gggccgattt
    10561 ttacttaccg gaacaccttt acccatgctc agttatcgcc acagctttca cgctggcaac
    10621 cacgccgacg tccttaaaca taccgttcag agcctgatca tcgagtcgct gaaagagaaa
    10681 gataaaccgt ttctctatct cgacacccac gcaggggccg ggcgttatca gttaggcagc
    10741 gaacatgccg agcgtaccgg cgaatatctc gaaggcatcg cccgtatctg gcagcaggac
    10801 gatttgcccg cagaactgga ggcgtacatc aatgtggtaa aacacttcaa ccgtagcggt
    10861 cagttgcgtt actaccccgg ttcgccattg attgctcgcc agctactgcg cgaacaagac
    10921 agcctgcaac tgaccgaact gcacccgagc gattacccgt tgctgcgttc tgaatttcag
    10981 aaagacagcc gtgcgcgcgt cgaaaaagcc gatggtttcc agcagcttaa ggccaaactg
    11041 ccgccggttt cccgccgtgg tttaatcctt atcgacccgc cgtatgaaat gaaaaccgac
    11101 tatcaggcgg tggtcagcgg gatagcagaa ggttacaaac gtttcgccac tggtacttac
    11161 gcactgtggt atccggtggt gctgcgtcag caaattaagc gcatgatcca cgatctggaa
    11221 gcgaccggta ttcgcaaaat tctgcaaatt gaactggcgg tactgccaga cagcgatcgc
    11281 cgtggcatga ccgcttccgg catgattgtg attaacccgc cgtggaaact ggaacagcag
    11341 atgaataacg tgctgccgtg gctgcacagc aaactggttc cggcaggcac cgggcacgcc
    11401 accgtaagct ggatcgtgcc ggagtaattg cagccattgc tggcacctat tacgtctcgc
    11461 gctacaatcg cggtaatcaa cgataaggac actttgtcat gactaaacac tatgattaca
    11521 tcgccatcgg cggcggcagc ggcggtatcg cctccatcaa ccgcgcggct atgtacggcc
    11581 agaaatgtgc gctgattgaa gccaaagagc tgggcggcac ctgcgtaaat gttggctgtg
    11641 tgccgaaaaa agtgatgtgg cacgcggcgc aaatccgtga agcgatccat atgtacggcc
    11701 cggattatgg ttttgatacc actatcaata aattcaactg ggaaacgttg atcgccagcc
    11761 gtaccgccta tatcgaccgt attcatactt cctatgaaaa cgtgctcggt aaaaataacg
    11821 ttgatgtaat caaaggcttt gcccgcttcg ttgatgccaa aacgctggag gtaaacggcg
    11881 aaaccatcac ggccgatcat attctgatcg ccacaggcgg tcgtccgagc cacccggata
    11941 ttccgggcgt ggaatacggt attgattctg atggcttctt cgcccttcct gctttgccag
    12001 agcgcgtggc ggttgttggc gcgggttaca tcgccgttga gctggcgggc gtgattaacg
    12061 gcctcggcgc gaaaacgcat ctgtttgtgc gtaaacatgc gccgctgcgc agcttcgacc
    12121 cgatgatttc cgaaacgctg gtcgaagtga tgaacgccga aggcccgcag ctgcacacca
    12181 acgccatccc gaaagcggta gtgaaaaatg ccgatggtag cctgacgctg gagctggaag
    12241 atggtcgcag tgaaacggtg gattgcctga tttgggcgat tggtcgcgag cctgccaatg
    12301 acaacatcaa cctggaagcc gctggcgtta aaactaacga aaaaggctat atcgtcgtcg
    12361 ataaatatca aaacaccaat attgaaggta tttacgcggt gggcgataac acgggtgcag
    12421 tggagctgac accggtggca gttgcagcgg gtcgccgtct ctctgaacgc ctgtttaata
    12481 acaagccgga tgagcatctg gattacagca acattccgac cgtggtcttc agccatccgc
    12541 cgattggtac tgttggttta acggaaccgc aggcgcgcga gcagtatggc gacgatcagg
    12601 tgaaagtgta taaatcctct ttcaccgcga tgtataccgc cgtcaccact caccgccagc
    12661 cgtgccgcat gaagctggtg tgcgttggat cggaagagaa gattgtcggt attcacggca
    12721 ttggctttgg tatggacgaa atgttgcagg gcttcgcggt ggcgctgaag atgggtgcaa
    12781 ccaaaaaaga cttcgacaat accgtcgcca ttcacccaac ggcggcagaa gagttcgtga
    12841 caatgcgtta aatgttaaag ggctaagagt agtgtgctct tagcccttaa ttacgtttcc
    12901 gctatcagtt cagaagctga agcagaaagc ggatcagttc cagcagcgca attaacgccc
    12961 caagaacgat gattgcttta tcaatcaccc gttttctcca tgcgatggag tgagaatgca
    13021 tccgcttact catccactgc ctgtcacggc gcatgcccta ttgttagata atggcattct
    13081 cactccggcc agagcatcag ttaacggcac cacccgtact tctgaccagg actttgaaag
    13141 cgtttatgcg cattaccaga gtgaaaatgc ctcagagcta actggataat catacagtac
    13201 attcaggtta taaaaccagc atgtccttgc aatagtttca gtatggtatt agcattgatg
    13261 cgttagataa tggcattctc actccagcca gtgccaccaa ctcagggctg gaaagtaaaa
    13321 aaccgacgca aagtcggttt ttttacatcc ggattcggac aaggcttaat atgacgatga
    13381 cccagtgaaa gtatataaat cgtcattgcg atatataccg aagtgccccc tccgccagct
    13441 gaagaaatcg ctaattcttg caatgttagc cactggctaa tagtattgag ctgttagata
    13501 agaactctct cactccagcc agagccacca actcagggct ggaaagtaaa aaaccgacgc
    13561 aaagtcggtt tttttacgtc ctgattcaga cctcctttca aatgaatagc caactcaaaa
    13621 ttcacaccta ttaccttcct ctgcacttac acattcgtta agtcatatat gtttttgact
    13681 tatccgcttc gaagagagac actacctgca acaatcagga gcgcaatatg tcatttctgt
    13741 tacccatcca attgttcaaa attcttgctg atgaaacccg tctgggcatc gttttactgc
    13801 tcagcgaact gggagagtta tgcgtctgcg atctctgcac tgctctcgac cagtcgcagc
    13861 ccaagatctc ccgccacctg gcattgctgc gtgaaagcgg gctgttgctg gaccgcaagc
    13921 aaggtaagtg ggttcattac cgcttatcac cgcatattcc agcatgggcg gcgaaaatta
    13981 ttgatgaggc ctggcaatgt gaacaggaaa aggttcaggc gattgtccgc aacctggctc
    14041 gacaaaactg ttccggggac agtaagaaca tttgcagtta aaaatttagc taaacacata
    14101 tgaattttca gatgtgtttt atccgggagg cattatgtta ctggcaggcg ctatctttgt
    14161 cctgaccatc gtattggtta tctggcagcc gaaaggttta ggcatcggct ggagtgcaac
    14221 gctcggcgca gtactggcgt tagttacggg cgtggtccat ccgggtgata ttccggtggt
    14281 gtggaatatc gtctggaacg cgacggctgc gtttatcgcc gtcattatca tcagcctgct
    14341 gctggatgag tccggctttt ttgaatgggc ggcgctgcac gtctcacgct ggggtaatgg
    14401 tcgtggtcgc ttgctgttta cctggattgt cctgctcggt gctgccgttg ccgccctgtt
    14461 tgccaatgat ggcgcggcgc ttattttgac accgattgtc atcgccatgc tgctggcttt
    14521 agggttcagt aaaggcacta cgctggcgtt cgtgatggcg gccggattca ttgccgatac
    14581 cgccagcctg ccgcttattg tctccaacct ggtgaatatc gtttccgctg atttctttgg
    14641 cctcggcttt cgcgaatacg cctcggtgat ggtgccggtg gatatcgccg cgattgttgc
    14701 cacgctggtg atgttacatc tctattttcg caaagatatt ccgcagaact acgatatggc
    14761 gctgctgaaa tctcccgcag aagcgatcaa agatcctgct acgttcaaaa ctggctgggt
    14821 tgttttactg cttctgctgg tgggattttt cgtcctggaa ccgctcggca ttccggtgag
    14881 cgccattgca gctgtgggcg cgctgatatt atttgtcgtc gctaaacgcg gtcatgcgat
    14941 taatacgggt aaagtcctgc gcggtgcccc ctggcagatt gtcatcttct cgctcggcat
    15001 gtatctggtg gtttatggcc tgcgcaatgc cggattaacg gaatatcttt ctggcgtact
    15061 caacgtgctg gcggataacg gcctgtgggc cgcgacgctc ggcaccggat tcctcaccgc
    15121 cttcctctct tctattatga acaatatgcc gacggtactg gttggcgcgt tgtccattga
    15181 tggcagcacg gcatctggcg ttatcaaaga agcgatggtt tatgccaatg tgattggctg
    15241 cgatttggga ccgaaaatta ccccaattgg tagcctggct acgctactct ggctgcacgt
    15301 actttcgcag aagaatatga ctatcagctg gggatattac ttccgtacag ggattatcat
    15361 gaccctgccg gtgctttttg tgacgctggc tgcgctggcg ctacgtctct ctttcacttt
    15421 gtaatgagat attgatatga gcaacattac catttatcac aacccggcct gcggtacgtc
    15481 gcgtaatacg ctggagatga tccgcaacag cggtacagaa ccgaccatta tctattatct
    15541 ggaaacaccg ccaacgcgcg atgagctggt caaactcatt gccgatatgg ggatttccgt
    15601 acgcgcgctg ttgcgtaaaa acgtcgagcc gtatgaggaa ctgggccttg cagaagataa
    15661 atttactgac gatcggttaa tcgactttat gcttcagcac ccgattctga ttaatcgccc
    15721 gattgtggtg acgccgctgg gaactcgcct gtgccgccct tcagaagtgg tgctggaaat
    15781 tctgccagat gcgcaaaaag gcgcattctc caaggaagat ggcgagaaag tggttgatga
    15841 agcgggtaag cggttgaaat aaagcggcga tatccactgc ccatagttgg taaagtgcgc
    15901 tttgtttatg tcggatgcga cgctaacgcg tcttatccga cctacaaaac cgtgcaaatt
    15961 caatatatgg catgaaatat gtagagcgta gcgcatcagg caattttgct atttacgcag
    16021 cactcctcgc gtaagaattc aattatcgct tccagcattg cgtattgcga aacacacatc
    16081 agcgtccgac tctcacggtt ttgtttgacc agtcctaccg ataccagtgc tgatatatgg
    16141 tggctgagtg tggagccagg tatcccaagc tgcttttgca actcaccgac cggcaaccct
    16201 tgttccccgg ctttgacaag atgtttaaat atgaacaaac gggtcgggtg acctagctct
    16261 ttcagcgctt tagcgacttc ttccaactgc atatgacacc cctctgtctg gttgatattt
    16321 cgataatacc agaaatatct tgatctgaat ttcatttcga ttattctgga aatatagatt
    16381 tatccaatga ggttacgtat gagtagttgg cttgcgatgc tgcaagatgc cgcagagatg
    16441 tttgtgtttc tcgccgtcga gctttcgttg ctgtttatag tgattagtgc cggtgtcagc
    16501 ctgataagac aaaaggtgcc agaccataaa atccagcaga tgatgggggc cagaaaaggg
    16561 agaggctatc tcctggctgc tctgttggga gccgttaccc cgttctgtag ttgctcgaca
    16621 atacccatgt tacgtggatt gttgtcagcg aaagccgggt ttggtccgac tctcactttt
    16681 ttatttgttt caccattact taatcccatt atcgtcggac taatgtggat gacctttggt
    16741 tggaaagtca ccttgttgta cgcgattatc gcagccggcg tctccgttct tgccagtatt
    16801 atcctggatt ctctggggtt tgaacgtcat atcattgcca gtaaaagctc atcagcaaat
    16861 tgttgtgctc cagcaaaaac ttcgccggga acgacatata cgcccataaa agtgagttgt
    16921 tgtagtccag cggctaaagc cattgagaac cccgtagtta cctgttgcag taccaaagct
    16981 gtagtaagta ttaatcccat aaaactagcc accaaagatg cgttgcaaca gtttaaagat
    17041 gtactgccat atcttttgtt aggagtatta ataggatctt ttatttatgg ctttattccc
    17101 tcagcgtgga ttgccgctca tgcaggagca gataatccct tcgccatccc attaagcgcc
    17161 gttgtcggta ttccgctgta tatccgggct gaggcagtta tccctctggc atctgttctg
    17221 atgacaaaag gaatgggtct gggagcatta atggcattaa tcatcggcag tgccggcgca
    17281 agcctgacgg aagtgatatt acttaaatca atgttcagaa tgccgatgat agctgcattc
    17341 ctgacggtta tattaggtat ggctatcttg atgggctatt tgactcaatt gctattttaa
    17401 atagatgcca gcagtaaact ataagatgca tagttagtgc catatccttc taagtagaaa
    17461 atcatagaca ggataatcct taaaaatcac aaatgattta actaatgcat tgagaatgat
    17521 gacggctcgg tcaacaagtc atcaacagac aataaccacg taatcatgct tctctgacat
    17581 tttatcggag aagcaatgac tctttgtctc agtaccctcc tcctttttaa aaggcagatt
    17641 tcagtcg
//
LOCUS       DAPGUL010000092        17527 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.093, whole genome shotgun sequence.
ACCESSION   DAPGUL010000092 DAPGUL010000000
VERSION     DAPGUL010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17527
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.093"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(283..1311)
                     /gene="epmB"
                     /locus_tag="RHX21_003331"
     CDS             complement(283..1311)
                     /gene="epmB"
                     /locus_tag="RHX21_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF-P beta-lysylation protein EpmB"
                     /protein_id="HDV1988477.1"
                     /translation="MAHIVTLNTPSREDWLTQLADVVTDPDELLRLLNIDADEKLLAG
                     RSAKKLFALRVPRSFIDRMEKGNPDDPLLRQVLTSQDEFVVASGFSTDPLEEQHSVVP
                     GLLHKYHNRALLLVKGGCAVNCRYCFRRHFPYAENQGNKRNWQTALEYVAAHPELDEM
                     IFSGGDPLMAKDHELDWLLTQLEAIPHIKRLRIHSRLPIVIPARITEALVERFARSTL
                     QILLVNHINHANEVDETFRQAMAKLRRVGVTLLNQSVLLRGVNDNAQTLANLSNALFD
                     AGVMPYYLHVLDKVQGAAHFMVSDDEARQIMRELLTLVSGYLVPKLAREIGGEPSKTP
                     LDLQLRQQ"
     gene            1353..1919
                     /gene="efp"
                     /locus_tag="RHX21_003332"
     CDS             1353..1919
                     /gene="efp"
                     /locus_tag="RHX21_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004871142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HDV1988478.1"
                     /translation="MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLR
                     RLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGD
                     NAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGA
                     VVKVPLFVQIGEVIKVDTRSGEYVSRVK"
     gene            1971..2096
                     /gene="ecnA"
                     /locus_tag="RHX21_003333"
     CDS             1971..2096
                     /gene="ecnA"
                     /locus_tag="RHX21_003333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein antitoxin entericidin A"
                     /protein_id="HDV1988479.1"
                     /translation="MMKRLIVLVLLASTLLTGCNTARGFGEDIKHLGNSISRAAS"
     gene            2207..2353
                     /gene="ecnB"
                     /locus_tag="RHX21_003334"
     CDS             2207..2353
                     /gene="ecnB"
                     /locus_tag="RHX21_003334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein toxin entericidin B"
                     /protein_id="HDV1988480.1"
                     /translation="MVKKTIAAIFSVLVLSTVLTACNTTRGVGEDISDGGNAISGAAT
                     KAQQ"
     gene            2528..2845
                     /gene="sugE"
                     /locus_tag="RHX21_003335"
     CDS             2528..2845
                     /gene="sugE"
                     /locus_tag="RHX21_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418572.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HDV1988481.1"
                     /translation="MSWIILVIAGLLEVVWAVGLKYTHGFSRLTPSVITVTAMIVSMA
                     LLAWAMKSLPVGTAYAVWTGIGAVGAAITGIVLLGESANPMRLASLALIVLGIIGLKL
                     STH"
     gene            complement(2842..3375)
                     /gene="blc"
                     /locus_tag="RHX21_003336"
     CDS             complement(2842..3375)
                     /gene="blc"
                     /locus_tag="RHX21_003336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin Blc"
                     /protein_id="HDV1988482.1"
                     /translation="MRLLPLVAAATAAFLVVACSSPTPPRGVTVVNNFDAKRYLGTWY
                     EIARFDHRFERGLEKVTATYSLRDDGGLNVINKGYNPDRGMWQQSEGKAYFTGAPTRA
                     ALKVSFFGPFYGGYNVIALDREYRHALVCGPDRDYLWILSRTPTISDEVKQEMLAVAT
                     REGFDVSKFIWVQQPGS"
     gene            complement(3464..4597)
                     /locus_tag="RHX21_003337"
     CDS             complement(3464..4597)
                     /locus_tag="RHX21_003337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaEC family class C beta-lactamase"
                     /protein_id="HDV1988483.1"
                     /translation="MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGM
                     AVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLS
                     DPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAP
                     GTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWG
                     YREGKAVHVSPGALDAETYGVKSTIEDMACWVRSNMNPRDINDKTLQQGIQLAQSRYW
                     QTGDMYQGLGWEMLDWPVNPDSIINGSGNKIALAAHPVKAITPPTPAVRASWVHKTGA
                     TGGFGSYVAFIPEKELGIVMLANKNYPNPARVAAAWQILNALQ"
     gene            complement(4660..5019)
                     /gene="frdD"
                     /locus_tag="RHX21_003338"
     CDS             complement(4660..5019)
                     /gene="frdD"
                     /locus_tag="RHX21_003338"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdD"
                     /protein_id="HDV1988484.1"
                     /translation="MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGL
                     FPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFY
                     GLAAILTVVTLIGIVTI"
     gene            complement(5030..5425)
                     /gene="frdC"
                     /locus_tag="RHX21_003339"
     CDS             complement(5030..5425)
                     /gene="frdC"
                     /locus_tag="RHX21_003339"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdC"
                     /protein_id="HDV1988485.1"
                     /translation="MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELI
                     FGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDE
                     KMGPEPIIKSLWAVTVVATIVILFVALYW"
     gene            complement(5436..6170)
                     /gene="frdB"
                     /locus_tag="RHX21_003340"
     CDS             complement(5436..6170)
                     /gene="frdB"
                     /locus_tag="RHX21_003340"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase iron-sulfur protein"
                     /protein_id="HDV1988486.1"
                     /translation="MAEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYI
                     KDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERD
                     LVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACP
                     QFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKH
                     VDPAAAIQQGKVESSKDFLIATLKPR"
     gene            complement(6163..7971)
                     /gene="frdA"
                     /locus_tag="RHX21_003341"
     CDS             complement(6163..7971)
                     /gene="frdA"
                     /locus_tag="RHX21_003341"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase (quinol) flavoprotein
                     subunit"
                     /protein_id="HDV1988487.1"
                     /translation="MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRS
                     HTVAAEGGSAAVAQDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGC
                     PWSRRPDGSVNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLD
                     ILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMAL
                     SHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLG
                     EPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICE
                     LAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRL
                     GSNSLAELVVFGRLAGEQATERAATAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWA
                     KIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIE
                     LGHGLNVAECMAHSAMARKESRGAHQRLDEGCTERDDVNFLKHTLAFRDADGTTRLEY
                     SDVKITTLPPAKRVYGGEADAADKAEAANKKEKANG"
     gene            8296..9273
                     /gene="epmA"
                     /locus_tag="RHX21_003342"
     CDS             8296..9273
                     /gene="epmA"
                     /locus_tag="RHX21_003342"
                     /EC_number="6.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P--(R)-beta-lysine ligase"
                     /protein_id="HDV1988488.1"
                     /translation="MSETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMS
                     QATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNE
                     EMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEID
                     PLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPAS
                     QASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQ
                     HPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA"
     gene            9492..10994
                     /gene="yjeM"
                     /locus_tag="RHX21_003343"
     CDS             9492..10994
                     /gene="yjeM"
                     /locus_tag="RHX21_003343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418580.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/gamma-aminobutyrate family transporter
                     YjeM"
                     /protein_id="HDV1988489.1"
                     /translation="MPHTIKKMSLIGLILMIFTSVFGFANSPSAYYLMGYSAIPFYIF
                     SALLFFIPFALMMAEMGAAYRKEEGGIYSWMNNSVGPRFAFIGTFMWFSSYIIWMVST
                     SAKVWVPFSTFLYGSDMTQHWRIAGLEPTQVVGLLAVAWMILVTVVASKGINKIARIT
                     AVGGIAVMCLNLVLLLVSITILLLNGGHFAQDINFLASPNPGYQSGLAMLSFVVFAIF
                     AYGGIEAVGGLVDKTENPEKNFAKGIVFAAIVISIGYSLAIFLWGVSTNWQQVLSNGS
                     VNLGNITYVLMKSLGVTLGNALHLSPEASLSLGVWFARITGLSMFLAYTGAFFTLCYS
                     PLKAIIQGTPKALWPEPMTRLNAMGMPSIAMWMQCGLVTVFILLVSFGGGTASAFFNK
                     LTLMANVSMTLPYLFLALAFPFFKARQDLDRPFVIFKTHLSAMIATVVVVLVVTFANV
                     FTIIQPVVEAGDWDSTLWMIGGPVFFSLLAMAIYQNYCSRMANKPELALD"
     gene            complement(11145..14468)
                     /gene="mscM"
                     /locus_tag="RHX21_003344"
     CDS             complement(11145..14468)
                     /gene="mscM"
                     /locus_tag="RHX21_003344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="miniconductance mechanosensitive channel MscM"
                     /protein_id="HDV1988490.1"
                     /translation="MRLIITFLMAWCLSWGAYAATAPDSKQITQELEQAKAAKPAQPE
                     VIEALQSALNALEERKGSLERIKQYQQVIDNYPKLSATLRAQLNNMRDEPRSVSPGMS
                     TDALNQEILQVSSQLLDKSRQAQQEQERAREIADSLNQLPQQQTDARRQLNEIERRLG
                     TLTGNTPLNQAQNFALQSDSARLKALVDELELAQLSANNRQELARLRSELAEKESQQL
                     DAYLQALRNQLNSQRQLEAERALESTELLAENSADLPKDIVAQFKINRELSAALNQQA
                     QRMDLVASQQRQATSQTLQVRQALNTLREQSQWLGSSNLLGEALRAQVARLPEMPKPQ
                     QLDTEMAQLRVQRLRYEDLLNKQPQLRQIHQADGQPLTAEQNRILEAQLRTQRELLNS
                     LLQGGDTLLLELTKLKVSNGQLEDALKEVNEATHRYLFWTSDVRPMTIAWPLEIAQDL
                     RRLISLDTFSQLGKASVMMLTSKETILPLFGALILVGCSIYSRRYFTRFLERSAAKVG
                     KVTQDHFWLTLRTLFWSILVASPLPVLWMTLGYGLREAWPYPLAVAIGDGVTATVPLL
                     WVVMICATFARPNGLFIAHFGWPRERVSRGMRYYLMSIGLIVPLIMALMMFDNLDDRE
                     FSGSLGRLCFILICGALAVVTLSLKKAGIPLYLNKEGSGDNITNHMLWNMMIGAPLVA
                     ILASAVGYLATAQALLARLETSVAIWFLLLVVYHVIRRWMLIQRRRLAFDRAKHRRAE
                     MLAQRARGEEEAHHHSSPEGAIEVDESEVDLDAISAQSLRLVRSILMLIALLSVIVLW
                     SEIHSAFGFLENISLWDVTSTVQGVESLEPITLGAVLIAILVFIITTQLVRNLPALLE
                     LAILQHLDLTPGTGYAITTITKYLLMLIGGLVGFSMIGIEWSKLQWLVAALGVGLGFG
                     LQEIFANFISGLIILFEKPIRIGDTVTIRDLTGSVTKINTRATTISDWDRKEIIVPNK
                     AFITEQFINWSLSDSVTRVVLTIPAPADANSEEVTEILLTAARRCSLVIDNPAPEVFL
                     VDLQQGIQIFELRIYAAEMGHRMPLRHEIHQLILAGFHAHGIDMPFPPFQMRLESLNG
                     KQTGRTLTSAGKGRQAGSL"
     gene            complement(14490..15458)
                     /gene="psd"
                     /locus_tag="RHX21_003345"
     CDS             complement(14490..15458)
                     /gene="psd"
                     /locus_tag="RHX21_003345"
                     /EC_number="4.1.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313166.1"
                     /note="Phosphatidylserine decarboxylase is synthesized as
                     a single chain precursor. Generation of the pyruvoyl
                     active site from a Ser is coupled to cleavage of a Gly-Ser
                     bond between the larger (beta) and smaller (alpha chains).
                     It is an integral membrane protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylserine decarboxylase"
                     /protein_id="HDV1988491.1"
                     /translation="MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKY
                     YKVDMKEAQKPDTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEED
                     KILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYV
                     PGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTIT
                     PPREGIIKRWTWPAGENDGSVALLKGQEMGRFKLGSTVINLFAPGKVNLVEQLESLSV
                     TKIGQPLAVSTETFVTPDAEPAPLPAEEIEAEHDASPLVDDKKDQV"
     gene            complement(15555..16607)
                     /gene="rsgA"
                     /locus_tag="RHX21_003346"
     CDS             complement(15555..16607)
                     /gene="rsgA"
                     /locus_tag="RHX21_003346"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313167.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small ribosomal subunit biogenesis GTPase RsgA"
                     /protein_id="HDV1988492.1"
                     /translation="MSKNKLSKGQQRRVNANHQRRLKTSKEKPDYDDNLFGEPDEGIV
                     ISRFGMHADVESADGDVHRCNIRRTIRSLVTGDRVVWRPGKPAAEGVNVKGIVEAVHE
                     RTSVLTRPDFYDGVKPIAANIDQIVIVSAILPELSLNIIDRYLVACETLQIEPIIVLN
                     KIDLLDDEGMAFVNEQMDIYRNIGYRVLMVSSHTQDGLKPLEEALTGRISIFAGQSGV
                     GKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHFPHGGDVIDSPGVREFGLW
                     HLEPEQITQGFVEFHDYLGLCKYRDCKHDTDPGCAIREAVEEGKIAETRFENYHRILE
                     SMAQVKTRKNFSDTDD"
     gene            16702..17247
                     /gene="orn"
                     /locus_tag="RHX21_003347"
     CDS             16702..17247
                     /gene="orn"
                     /locus_tag="RHX21_003347"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoribonuclease"
                     /protein_id="HDV1988493.1"
                     /translation="MSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGP
                     TIAVHQSDEQLALMDDWNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVPAGKS
                     PICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQA
                     MDDIRESVAELAYYREHFIKL"
BASE COUNT         4030 a         4520 c         4619 g         4358 t
ORIGIN      
        1 cactctatat aaacagaaaa gaaaggttaa ttattggtgt tggctatata aagagtaaca
       61 acagcaatgt atatgaataa ttaaaggtta tgcaacgggc aaagattaaa tttcccagtt
      121 taatgacagg ttgctgtact tgcgtttgtt gctcttgccg gatgcggcgt aaacgcctta
      181 tccggcctac agttcattgc aaatccattc aatttcaatg cacaatgtag gcctgataag
      241 cgtagcgcat caggctaatg tttaacttcc ctgtttaatc agttactgct ggcgtagctg
      301 gagatccagc ggcgttttgc tgggttcgcc gccgatttct cgcgccagtt tcggcaccag
      361 ataacccgac accagtgtca gcaactcacg cataatctgc cgtgcttcgt catcactcac
      421 cataaaatgc gccgcgccct gtactttatc tagcacatgc aggtaatacg gcatcacgcc
      481 ggcatcgaac aacgcattac tcaggtttgc cagcgtttgt gcgttatcgt tcacaccacg
      541 taacagaacg ctctggttaa gcagggtgac accgacacgg cgcaatttag ccatcgcctg
      601 acggaacgtt tcatctacct cattggcatg attgatgtga ttcaccagca agatttgcag
      661 cgtagaacgg gcaaagcgtt caaccagcgc ctcggtgata cgtgccggga tcacaatcgg
      721 cagacggctg tgaatccgca gacgtttgat atgcgggatg gcttccagtt gtgtgagcaa
      781 ccagtccagc tcgtgatctt tcgccatcag cggatcgccg ccggagaaaa tcatctcgtc
      841 cagttccgga tgcgcagcaa catactcaag agcagtctgc cagttacgct tgttgccctg
      901 attttcggca taggggaagt ggcgacggaa gcaatagcgg caatttaccg cgcagccgcc
      961 tttgaccagc aaaagcgccc ggttgtggta tttatgcaac aaaccaggca ctacgctgtg
     1021 ctgttcttcc agcgggtcgg tggagaatcc ggacgcgacg acaaactcat cttgcgaggt
     1081 aagtacctga cgcaaaagag gatcgtccgg attgcctttc tccatgcgat cgataaatga
     1141 gcggggcaca cgcagggcaa acagcttttt ggcgctgcgt ccggccaaca gtttttcgtc
     1201 cgcgtctata ttcaaaagac gcagaagttc atcaggatcg gtcacaacat cggcaagttg
     1261 cgttaaccaa tcttctctgg atggggtatt tagggttaca atatgcgcca ttttgtggct
     1321 tagctaccaa ttaacaaatt tcagagggcc ttatggcaac gtactatagc aacgattttc
     1381 gtgctggtct taaaatcatg ttagacggcg aaccttacgc ggttgaagcg agtgaattcg
     1441 taaaaccggg taaaggccag gcatttgctc gcgttaaact gcgtcgtctg ctgaccggta
     1501 ctcgcgtaga aaaaaccttc aaatctactg attccgctga aggcgctgat gttgtcgata
     1561 tgaacctgac ttacctgtac aacgacggtg agttctggca cttcatgaac aacgaaactt
     1621 tcgagcagct gtctgctgat gcaaaagcaa ttggcgacaa cgctaaatgg ctgctggatc
     1681 aggcagagtg tatcgtaact ctgtggaatg gtcagccgat ctccgttact ccgccgaact
     1741 tcgttgaact ggaaatcgtt gataccgatc cgggcctgaa aggtgatacc gcaggtactg
     1801 gcggcaaacc ggctaccctg tctactggcg ctgtggttaa agttccgctg ttcgtacaaa
     1861 tcggcgaagt catcaaagtg gatacccgct ctggtgaata cgtctctcgc gtgaagtaat
     1921 gcggttgtgg tgcggcctgc aggctgcacc atcacttatt caggtcagag atgatgaaac
     1981 gccttatcgt tcttgttttg cttgccagca cgctgctcac gggctgtaac accgctcgcg
     2041 gtttcggcga agacatcaaa catctcggca actccatctc tcgcgctgcc agctaatttt
     2101 tcttctcttc cgaaaaatca tcagatttcc atcatttttg gcgatgttgt ctattattaa
     2161 tttgctatag gcaaacataa ataacattac ctaaaaggaa gacgttatgg tgaagaagac
     2221 aattgcagcg atcttttctg ttctggtgct ttcaacagta ttaactgcct gcaacaccac
     2281 gcgtggcgtt ggtgaagaca tttctgatgg cggtaacgcg atttctggtg cagcaacgaa
     2341 agcgcagcaa taagcaataa cggtacgaca gttatgtcgt gccgtttgtt tttttgcgat
     2401 agtcacaaag gtaatagttg aaattcccct gccacctggc aaaatatccg ttcaaccatc
     2461 agctttgcag gacgacctgc aaacgcctct tttcaccggg gacggcccca attctccgga
     2521 gcctgatatg tcctggatta tcttagttat tgctggtctg ctggaagtgg tatgggccgt
     2581 tggcctgaaa tatacccacg gctttagtcg tttgacgcca agtgttatta ctgtgacggc
     2641 gatgatagtc agtatggcgc tacttgcctg ggcgatgaaa tcgttaccgg tagggacggc
     2701 ttatgccgtg tggacgggta ttggcgcagt cggcgcggcc atcaccggca ttgtgctgct
     2761 cggtgagtcc gctaacccga tgcgcctggc gagtctggcg ttaatcgtat tggggattat
     2821 tggtctgaaa ctcagcactc actaactacc gggctgctgt acccaaataa acttactgac
     2881 atcaaaccct tcccgggtcg cgactgccag catctcctgt ttcacttcgt cagaaatggt
     2941 tggcgtgcgg gagagtatcc acaggtagtc gcggtccggg ccgcaaacca gcgcatggcg
     3001 gtattcccga tcgagtgcaa taacgttata accgccatag aaaggaccaa agaatgacac
     3061 tttcagcgca gcgcgagttg gtgcgccggt aaagtacgct ttcccttcac tctgctgcca
     3121 cattcctctg tcagggttat agcctttatt aatgacattc aggccgccgt catcacgcag
     3181 gctgtatgtt gcggtgactt tttccagtcc acgttcaaaa cggtgatcaa aacgggcaat
     3241 ctcataccag gtaccgagat aacgtttggc gtcgaaatta ttcactactg ttacgccacg
     3301 cggcggcgta ggagaactgc aggcaacgac cagaaatgca gctgtcgctg cggcaacgag
     3361 agggagcagg cgcataaatg tttccttact ggtttttttc taagtgtaga tgacagcaag
     3421 gaaaagcgca gaaaaggtcc gaaaattcgg acccgatgaa attttactgt agagcgttga
     3481 gaatctgcca ggcggcggcg actctcgctg gattgggata gtttttgtta gccagcatca
     3541 ctatacccag ctctttttct ggaataaacg cgacatagct accaaatccg ccggttgccc
     3601 ctgttttatg tacccatgat gcgcgtactg caggagttgg gggcgtaatc gcttttacgg
     3661 ggtgtgctgc cagtgcaatt ttattgccac tgccgttaat gatgctgtca ggatttaccg
     3721 gccagtccag catttcccag cccaggccct gatacatatc gccggtttgc cagtagcgag
     3781 attgtgccag ttgtatccct tgctgaagtg ttttgtcgtt gatatcacgg ggattcatat
     3841 tgcttcgtac ccagcaggcc atatcttcaa tggtcgactt cacaccataa gtttcagcat
     3901 ctaacgcccc tggcgaaaca tgaactgcct tgccttcgcg atatccccag gcgtaattct
     3961 tttcttctgc gggcggtaca ttaatccacg tatggttgag tttgagtggc tggaagacac
     4021 gtgtttgcat cgcctgctca aaactcaaac cagacggctt cacagccagt gcgccgaaca
     4081 aaccgatact ggagttggca tacagacgtt gtgttcctgg cgcccatgca ggctgccagt
     4141 tttgatagaa gcgcagcaag tcgcttgagg atttcacctc atccggcacc tgcaatggca
     4201 ggccgccagc agtgtaggtt gcgagatgta atagtgtgat cccattccac tgtttagcgg
     4261 taagttcagg ccagtatttt gttgtgggat cgcttaactt gatttcccct cgagcaatag
     4321 cgtcgccacc aagcacgccc gtaaatgttt tgctgaccga acctaactca aacaacgttt
     4381 gctgtgtgac gggctgcttt ttggcgatgt ccgcatagcc ccaggtaaag taataaggtt
     4441 taccctgata aattaccgcc accgccatac cggggatctt ttgttgctct ataagcgggg
     4501 taattgtgcg atgcacaata tcgttgattt gttgaggggc agcaaatgtg gagcaagagg
     4561 cggtaattaa taaggcgcag agcgtcgttt tgaacataag gtctggtttc catacaaaac
     4621 ggcccgccat aggcgggccg gatttacatt ggcgatacgt tagattgtaa cgataccaat
     4681 cagcgtgaca actgtcaaga tagcagccag accgtagaaa acccatttgc ccgcaggcac
     4741 gtgaattttc agatcgtgca tcgcgtggtg catacggtgt aaaccacacc acagcggcag
     4801 aacgatcatc aggaacagga atacgcgacc aatgaagctc tgcgcgaacg ccagaacgcg
     4861 ctcgtagctc agcgcatcac ccggaaacag ccccagtggc agcagaatac ccaccagcag
     4921 gatcatcacc ggcgcaataa ttgcgctcca cataccaccg gccccgaaga ggccccagaa
     4981 taccggttcg tcagaacgct ttggatttgg attaatcatc tcaggctcct taccagtaca
     5041 gggcaacaaa caggattacg atggtggcaa ccacagttac cgcccagaga cttttgataa
     5101 ttggctctgg tcccattttt tcgtctttta caatgatatt ggctgctttc ggtgccagtt
     5161 caaaccaggt tttggtatgc agcagagctg ccgccagagt gatcaggtta atgatcacga
     5221 taaccgggtt ttgtaaaaag tcgacgaatc ccgcccaggc ttccgggcca tttttcaggg
     5281 caaacagccc gaaaatcagt tcaatgctga accacacagc cggaaccgcc gtgccttcgc
     5341 gcagcatgta aaagcgataa aacggcaatt ttttccacca ggtggacgtc attggccgta
     5401 catacggttt acgtttagtc gtcatgttgc actccttagc gtggtttcag ggtcgcgata
     5461 agaaagtctt tcgaactttc tactttgccc tgctgaatgg ccgcagccgg atcgacgtgt
     5521 ttcgggcaga cttcggagca atagcccacg aaagtacagc tccatacgcc gttctggctg
     5581 ttcaactgcg ccatacgctc cttcttaccg tggtcgcggc tatcttcgtt ataacgatgc
     5641 gccagcgtaa tggcagccgg accgatgaac tctgggttca ggccaaactg cgggcacgcg
     5701 gcgtagcaca gaccacagtt gatgcaaccg gagaactggt gatactttgc catctgcgcc
     5761 ggggtctgga tgttagtacc ctgatccgcg gtgcgggagt tgccgatgat gtacggtttg
     5821 atcgcttcca gactttcgat gaagtgggtc atatcgacca ccagatcgcg ttcaatcggg
     5881 aagttagcta acgcttcaac cttcataccg tcggtgtaat cacgcaggaa ggttttacat
     5941 gccagttttg gcacgttgtt aaccatcatg ccgcaggaac cacaaatcgc catacggcag
     6001 gaccagcggt aactcaggtc cggtgccagg ttgtctttga tgtagcccag cgcatccagt
     6061 aatgaggtag ttgcgtcata aggcacttca tagaatgcgc tatgcggtgc ggtatcgact
     6121 tccgggttat agcgcaccac ctcaattttc aggtttttca tctcagccat tcgccttctc
     6181 cttcttattg gctgcttccg ccttatcggc tgcatccgct tcgccaccgt aaacgcgttt
     6241 agctggcggc agcgtagtaa tcttcacgtc gctgtactcc aggcgagtcg tgccatcagc
     6301 atcgcggaag gcgagggtgt gtttgaggaa gttgacgtcg tcacgctcgg tgcaaccttc
     6361 gtccagacgc tggtgtgcgc cgcgggactc tttacgtgcc attgcggagt gcgccataca
     6421 ttcagcaacg ttcagaccgt ggcccagttc aatggtgtag agcaggtcgg tgttgaacac
     6481 gctggaggtg tcggtgatgc gcacgcgctt gaagcgttcc tgcagctctg ccagcttgtc
     6541 gatggttttc tgcatcagtt ccggcgtacg gtagataccg caaccttctt ccatagccag
     6601 acccatttcg tcgcggatct tcgcccagtt ttcgccgcca tcctggttaa ccagatcttt
     6661 cagacgttgt tcaacgccag ctgcctgcgc ttcaattgcc gcttcgttgc cattaccggc
     6721 agttgctgca cgctctgtcg cttgttcacc ggccagacgg ccgaagacca ccagttccgc
     6781 cagggagttg gagcccagac ggtttgcacc gtgcagacca acagaggaac attcacccac
     6841 ggcgaacaga cctttaatgc gggtttcaca gttctgatcg gtttcgatac cgcccatggt
     6901 gtagtgtgcg gtcggacgta ccggaatcgg ttctttaacc ggatcgacgc caacgtacgc
     6961 tttcgccagt tcgcagatga acggcagacg ttcatgcagt tttttctcgc cgaggtgacg
     7021 caggtcgaga taaaccacat cgccacgcgg cgtggagatg gtgttgcctt tacgccattc
     7081 gtgccagaag gcctgagaaa ctttgtcgcg tggacccagt tccatatatt tgtttttcgg
     7141 ctcgcccagc ggagtttccg ggcccatgcc gtaatcttgc agataacggt agccattttt
     7201 gttgaccaga ataccgcctt caccgcggca gccttcggtc atcaggatac cggaacctgg
     7261 cagaccggtt gggtgatact gaacgaattc catgtcacgc agcggaacgc cgtggcttag
     7321 cgccataccc ataccgtcac cggtaacgat gccgccgttg gtgttgtaac gataaacgcg
     7381 acccgcaccg ccagtagcca taacgaccgc gttagcacgg atctgcacca gcgtgccttc
     7441 catcatgttc attgctacca ggccgcgaac atgaccatca tcaaccagaa tatccagcac
     7501 gaaatgttcg tcaaaacgct ggatctgcgg gaattgcaga gaggtctgga acagcgtgtg
     7561 cagcatatgg aagccggtct tatcggcggc gaaccaggtg cgctcgattt tcatgccgcc
     7621 gaagcgacgt acgttgacgc taccatccgg gcgacggctc catgggcacc cccacagttc
     7681 cagttgggtc atttcggttg ggcagtggtg gacgaaataa tccacgacat cctgctcaca
     7741 caaccagtcg ccacccgcta ctgtatcgtg aaagtgatat tcgaagctgt catgatcctg
     7801 cgcgacagcg gcggagcccc cttctgcagc aacggtatgg ctacgcatcg ggtatacttt
     7861 tgagattagt gcgatttttg catttggatt tgcctgcgcg gcagcaattg cagcacgtaa
     7921 tcccgcgcca ccggcgccta caatggcaag atcggcttga aaggtttgca cgacattcct
     7981 ccagattgtt tttatcccac agccccgtac ttcagggtaa gtgcctgaaa gttacggtct
     8041 gcgaacgcta ttccactgct cctttatagg tacaacagta tagtctgatg gataagtctg
     8101 aaatttgacg agatcgattt ttttagtgcg caagagggct aaattatcac tgaagatgat
     8161 taatttaatt actaaaccat cagatcgtgc tttttttagt cactgcccac cgctgtttga
     8221 ttcctgcgta aaatttgtct cgccgtcgcg ttgcgagtag acttcgtgcc cttgtcaaaa
     8281 actggagatt taactatgag cgaaacggca tcctggcagc cgagcgcatc cattcctaac
     8341 ttattaaaac gcgcggcgat tatggcggag atccgtcgtt tctttgccga tcgtggagtg
     8401 ctggaggtgg agacgccttg tatgagccag gcgacggtaa ccgatattca tttggtcccg
     8461 tttgagacac gtttcgttgg ccccgggcat tcgcagggga tgaatctctg gttaatgacc
     8521 agcccggaat accatatgaa acgcctgctg gttgccggtt gtgggccggt attccagctg
     8581 tgccgcagct tccgtaatga agagatgggg cgttatcaca accctgagtt cactatgctg
     8641 gagtggtatc gaccgcacta tgatatgtac cggttgatga acgaggtgga cgatctctta
     8701 caacaggtgc tggactgccc ggcagcagaa agcctttctt atcaacaagc tttcttgcgt
     8761 tatctggaaa ttgacccgct ctctgccgac aaaacgcaac tgcgggaagt cgcagcgaaa
     8821 ctggatttga gcaatgttgc tgataccgaa gaagaccgcg acacgctgct acaattgctg
     8881 tttacctttg gcgtagagcc aaatattggc aaagaaaaac cgacctttgt gtaccacttt
     8941 ccagccagcc aggcatcact ggcgcaaatc agtaccgaag atcatcgggt cgctgaacgc
     9001 tttgaggttt attataaagg tattgagctg gcgaatggtt tccatgaatt gacggatgcc
     9061 cgtgagcagc aacaacgctt tgaacaagat aaccgtaagc gcgcggcgcg cggtttgccg
     9121 cagcacccca ttgaccagaa tctgattgaa gccttgaaag tcggtatgcc tgactgttcc
     9181 ggcgtggcat taggtgttga tcgtctggtg atgttggcgc tgggcgcgga gacactggct
     9241 gaagtcatcg cctttagcgt tgaccgggca taattctgaa aaattactga attaacagcg
     9301 aagaatggcg tgataagcgc cattctgtag catatgtttt catttttccg ttaaaggcca
     9361 caatttaaga ctggatattt gatatcatcc aggtatcaat tctgtattgg tttttacgct
     9421 gcccgctcaa tgttgggcag tgcagttcag tgggcgcgtt ttatacacgc gctgaaatga
     9481 aggatggttt catgcctcac acgataaaaa agatgagtct gataggactc atattgatga
     9541 tctttacttc cgtatttgga tttgccaata gcccatcggc ttattactta atgggttata
     9601 gtgcgattcc cttttatata ttttctgcat tgttattctt tattccattc gccttaatga
     9661 tggctgaaat gggagctgcc tatcgcaaag aagaaggtgg tatctattcc tggatgaata
     9721 atagtgtcgg accacgtttt gccttcattg gtacgtttat gtggttttcc tcttatatca
     9781 tctggatggt gagtacctcc gcgaaagttt gggtaccgtt ctcaacattc ctctatggta
     9841 gcgacatgac ccagcactgg cgtattgctg gactggagcc tacgcaggtg gttggtctgc
     9901 tggcagtggc atggatgatt ctggtcaccg tcgttgcttc aaaggggatt aataaaattg
     9961 cccgcattac tgcggtgggc ggtattgcag taatgtgtct gaatttagta ttgctgttag
    10021 taagcattac tattttgtta ttaaatggtg ggcatttcgc gcaggatatt aatttccttg
    10081 catcaccgaa cccaggttat cagtccggtc tggcaatgct atcgtttgtg gtatttgcta
    10141 tttttgccta tggcggaatt gaagcggttg gtggtctggt cgataaaacg gaaaatccag
    10201 aaaagaactt tgccaaaggt attgtttttg ccgctattgt tatttcaatc ggttattcgc
    10261 tggcaatatt tttatggggt gtcagcacaa actggcagca ggtattaagt aatggttccg
    10321 ttaacctcgg caatattacc tatgtgctga tgaagagcct cggggtgacg ctgggtaacg
    10381 cactgcattt gtcacctgaa gcgtcattgt cgctgggtgt atggtttgcg cgtattaccg
    10441 gactttcgat gttcctcgct tataccgggg cgttctttac gctttgctat tcaccgctga
    10501 aagccatcat ccaggggacg ccgaaagcgt tgtggccgga accgatgacg cgcctgaatg
    10561 cgatggggat gccttctatc gccatgtgga tgcagtgcgg gttggttact gtcttcatcc
    10621 tgctggtttc gtttggtggc ggtaccgcat cggcgttctt taacaagctg acgctgatgg
    10681 cgaacgtgtc tatgacgctt ccttacctgt tcctcgcgct ggctttcccg ttctttaaag
    10741 cacgtcagga tctcgacaga ccgtttgtga ttttcaaaac gcatttgtcg gcaatgattg
    10801 cgacagtggt tgtcgtactg gtggtgacat ttgcgaacgt cttcaccatc attcaacctg
    10861 tggttgaagc cggagactgg gacagcacat tgtggatgat tggcggccct gtcttcttct
    10921 cgctgttagc gatggcgatt taccagaact attgcagtcg catggcgaat aaacctgagt
    10981 tagctctcga ctgatcatat gaaatcctgc aactcatcgt ctctccggcg atgagttgtc
    11041 aggaagtaat gcgtatggat gatactctcc agggccggtg ataactgaag atgatgttaa
    11101 gctgctaaat gagccacgtt gacatcattt ggcagcttca tgcattacaa acttcccgcc
    11161 tgacgacctt tgcccgcaga agttaatgtt ctccccgttt gcttaccgtt gaggctttcc
    11221 agacgcatct ggaagggcgg gaatggcata tcgataccgt gggcgtggaa gcctgccaga
    11281 atcagctggt ggatctcatg gcgtagcggc atacggtgac ccatctcagc ggcgtaaata
    11341 cgcagctcga aaatctgaat cccctgttgc agatccacca ggaagacttc cggtgccggg
    11401 ttgtcgatca ccagcgagca gcgacgcgct gcggtgagca ggatttccgt cacttcttcg
    11461 ctattggcat cggcaggggc cggtatcgtc aacaccacgc gcgtgaccga gtcagagagc
    11521 gaccagttga taaactgctc ggtaataaac gccttgttcg gcacgattat ctctttacgg
    11581 tcccagtcgc tgatggtggt ggcgcgggtg ttaattttcg tcacgctacc ggtaagatcg
    11641 cggatcgtta ccgtatcgcc aatgcgaatc ggtttttcga acaggataat caggccagag
    11701 ataaagttgg cgaaaatctc ctgcaaacca aaaccgagac caacaccgag cgcggcaacc
    11761 agccactgca atttcgacca ctcaatacca atcatcgaga agccgaccag cccgccaatc
    11821 agcatcagca gatatttggt gatggtggtg atggcgtagc ccgtacccgg cgttaaatcc
    11881 aggtgctgca aaatcgccag ttccagcagc gcgggcaggt tgcgcaccag ctgcgtggtg
    11941 atgataaaca ccagaatggc aatcagcacc gcaccgaggg taattggctc cagactttct
    12001 acgccctgta ccgtggaggt gacatcccac agcgaaatat tttcgaggaa gccgaaagcg
    12061 gaatggattt ctgaccacag cacaatgaca gaaagcaggg cgatcaacat caaaattgag
    12121 cgcaccagcc gcaaggattg cgcactgatg gcatcgagat cgacttcgct ttcatcgact
    12181 tcaattgccc cttccgggct actgtgatga tgcgcttcct cttcgccacg cgcgcgttgc
    12241 gctaacatct ctgcccggcg atgcttcgcc cggtcaaacg ccagcctgcg acgctggatc
    12301 agcatccagc ggcggataac gtgataaacc accagtagca ggaaccagat ggcaaccgag
    12361 gtttcaagcc tcgctaacag tgcctgcgcc gttgccagat aacccaccgc tgacgccaga
    12421 atggcaacca gtggtgcgcc aatcatcatg ttccacagca tatggttggt aatgttgtcg
    12481 ccgctgccct ctttgttgag gtacagcggg atcccggcct ttttcaggct gagggtgacc
    12541 accgccagcg caccgcaaat gaggataaag caaagccgtc ccagcgaacc ggagaattca
    12601 cggtcgtcga ggttatcgaa catcatcagc gccataatca gcggcacaat aagcccgatg
    12661 ctcatcaggt agtagcgcat cccacgggaa acacgttcgc gcggccagcc aaaatgagcg
    12721 ataaacaagc cgttcgggcg ggcaaaggtg gcgcaaatca tcactaccca cagcagcggc
    12781 acggtggccg ttacgccatc gccaatcgcg accgccagcg gataaggcca cgcctcgcgc
    12841 aagccgtaac ccagcgtcat ccacagcacc ggcagcggtg acgcgacgag aatcgaccag
    12901 aaaagagtgc gcaacgtcag ccagaagtga tcctgagtca ctttgccgac tttcgccgcc
    12961 gaacgttcaa gaaaacgggt gaaatagcgg cgcgagtaaa tactgcaacc gaccagaatc
    13021 aacgcgccaa acagcggcaa aatcgtctct ttgctggtca gcatcatcac gctggcttta
    13081 cccaactgac tgaaggtgtc cagcgagatg aggcggcgca gatcctgggc gatttccagc
    13141 ggccaggcga tagtcatcgg gcgcacgtca gaggtccaga acagatagcg gtgcgtcgct
    13201 tcgttcacct ctttcagcgc atcctccagt tgcccgttgg agactttcag cttggtcagt
    13261 tccagcagta gcgtgtctcc accctgcaac aatgagttca gcaactcacg ctgagtgcgt
    13321 agctgtgctt ccagaatacg gttttgctcg gcggtcagcg gctgaccgtc ggcctgatga
    13381 atttgcctta gctgcggctg tttattaagc agatcctcat aacgtaaccg ttgcacacgc
    13441 aactgcgcca tttcggtatc aagttgttgt ggttttggca tttccggcag ccgtgccacc
    13501 tgcgcccgca acgcttcgcc gagcaggttg gacgagccca gccattgcga ctgttcacgc
    13561 agcgtattca acgcctgccg gacctgtaac gtctggctgg tggcctggcg ctgttgcgag
    13621 gcaacgagat ccatccgctg cgcctgttga ttcagtgccg ccgatagttc gcggttaatt
    13681 ttgaattgcg cgacgatatc tttcggcaaa tcggcactgt tttctgccag taattcggta
    13741 ctttccagcg cccgctccgc ctcaagctga cgttggctat tcaactgatt acgtaaggcc
    13801 tgcaaatacg catccagttg ctggctctct ttttccgcca gctctgagcg caagcgcgct
    13861 aattcctgac ggttattggc agacagctgc gccagttcca gttcatcaac gagcgctttc
    13921 aggcgtgcgg agtcagactg caacgcgaaa ttttgtgcct gattgagcgg agtattgccg
    13981 gtaagcgttc ccaggcggcg ctcgatctca tttaactgac ggcgggcatc ggtttgctgt
    14041 tgcggcagtt gattcagtga atcggcaatc tcgcgggcgc gctcctgctc ttgctgggcc
    14101 tgacggctct tatccagcaa ctgactgctg acctggagaa tttcctgatt cagcgcatcg
    14161 gtagacattc ccggcgacac gctgcgcggc tcgtcacgca tgttgtttaa ttgtgcgcgc
    14221 agagtagcgg agagtttcgg gtaattatcg ataacttgct gatattgttt gatgcgctca
    14281 agggaacctt ttcgttcctc aagcgcattt aaggcagact ggagtgcctc tatgacttct
    14341 ggctgcgcgg gtttcgccgc ttttgcctgc tccagttcct gggtgatttg tttgctatcg
    14401 ggggccgtcg cggcgtacgc cccccaactg aggcaccagg ccatcagaaa agtgataatc
    14461 aggcgcacgt cagcgtttcc tttgatggat tagacctggt cttttttgtc gtcaaccaat
    14521 gggctggcgt cgtgttctgc ttcgatctct tcagcaggaa gcggggcagg ttcagcgtct
    14581 ggcgtaacaa aggtttcggt agatactgcc agcggctggc caattttcgt gacagacagg
    14641 ctttccagtt gctcaaccag attcacttta cccggtgcaa acaggttgat aacggtggaa
    14701 ccgagtttaa agcgacccat ttcctggcct ttaagcagtg ccacagaacc gtcgttttcc
    14761 ccggcaggcc aggtccagcg cttgatgata ccttcgcgcg gcggcgtaat ggtgcccgcc
    14821 cagaccgtct caatgctgcc aacaatcgtc gctccgacca gaatctgcgc cattgggcca
    14881 aattcggtat cgaaaaggca aatcacgcgt tcgttacggg caaacagatt cggcacgttc
    14941 tgagcggtga gatggttaac ggagaagaga tcgcccggca cgtagatcat ctcacgcaga
    15001 ataccgttgc acggcatgtg tacgcggtgg tagtcacgcg gggagaggta agtggtcaca
    15061 aacgtaccgt tgcggaacag gtccgccatc agatagttgc ctgccagcaa ggcttcgagg
    15121 ctgtagttgt ggcctttggc ttgcaggatt ttatcttctt cgattttacc caactggctg
    15181 ataacgccat cggcaggcat gaccaggaca ttcggatcgg tatcgattgg gcgtacttcg
    15241 tcacgcagcg gacggacaaa gaattcgtta aaggtgcggt agctggcggt gtccggcttt
    15301 tgcgcctctt tcatgtcgac cttgtagtat ttaacgaaca gatcgataac cagttttgtc
    15361 agccatcctg cccgcttgct tgcgccccaa cccgccaggc gagtaagcca tagtttcggc
    15421 agaatgtact gtagcgaaag tttaaatgaa tttaacaagg tagcctccag gccattgttt
    15481 tgtcgttcct gatccggcct acatgccgga tcctgaaaaa aaggggacga ttctaacgac
    15541 ggttagctta attgtcagtc atccgtatca gaaaagtttt tacgcgtttt tacctgcgcc
    15601 atgctttcca gaatacggtg atagttttcg aaacgggttt ccgcgatttt tccttcctca
    15661 accgcttccc ggatagcgca gcccggatcg gtatcgtgtt tgcaatcgcg atatttacac
    15721 agacctaaat agtcatggaa ttcgacaaag ccctgagtga tttgttccgg ctccaggtgc
    15781 cagaggccga actcacgcac accaggggaa tcaatcacat caccgccgtg cgggaagtga
    15841 tacagtcgtg cggcggtcgt ggtgtgctga ccgagacccg agttgtcaga gacatcgttg
    15901 gtcaggatct ctttttgcag ccccagcaac gcgttcagca ggctggattt gccgacgcca
    15961 gactggccgg caaaaatgct gatgcgcccg gtcaacgcct cttccagcgg ttttagccca
    16021 tcctgagtat ggctggaaac catcaatacg cgataaccaa tgttgcggta gatatccatc
    16081 tgctcgttga cgaacgccat gccttcgtcg tccagcaggt ctatcttatt gagcacaata
    16141 atcggctcaa tctgcaaggt ttcgcaggcc accaggtaac ggtcgataat attgagcgac
    16201 agctccggca aaatggcgga gacaatgaca atctggtcga tgttggcggc aataggtttc
    16261 acgccgtcgt agaaatccgg acgcgtcaac actgaggtgc gctcatgcac cgcttccacg
    16321 atccctttga catttacgcc ttccgccgcc ggtttacccg gacgccagac tacgcggtcg
    16381 ccggttacca gcgaacggat ggtacggcga atattgcagc ggtgaacgtc gccatcggcg
    16441 gattccacat cagcgtgcat accaaagcgg ctgatgacga taccttcatc aggctcgcca
    16501 aacagattgt cgtcgtagtc gggcttctcc ttagacgttt taagacgacg ctggtgattg
    16561 gcgttcacgc ggcgctgctg gcctttggag agtttatttt tactcaatcg tacagactcc
    16621 tggtcgcccc tgatgggcaa aacatctatg atacacgcaa ttgtggatca atatagtcac
    16681 tgtgaatggg tggaaaatag catgagtgcc aatgaaaaca acctgatttg gatcgatctt
    16741 gagatgaccg gtctggatcc cgagcgcgat cgcattattg agattgccac gctggtgacc
    16801 gatgccaacc tgaatattct ggcagaaggg ccgaccattg cagtacacca gtctgatgaa
    16861 cagctggcgc tgatggatga ctggaacgtg cgcacccata ccgccagcgg gctggtagag
    16921 cgcgtgaaag cgagcacgat gggcgatcgg gaagctgaac tggcaacgct cgaattttta
    16981 aaacagtggg tgcctgcggg aaaatcgccg atttgcggta acagcatcgg tcaggaccgt
    17041 cgtttcctgt ttaaatacat gccggagctg gaagcctact tccactaccg ttatctcgat
    17101 gtcagcaccc tgaaagagct ggcgcgccgc tggaagccgg aaattctgga tggttttacc
    17161 aagcagggga cgcatcaggc gatggatgat atccgtgaat cggtggcgga gctggcttac
    17221 taccgcgagc attttatcaa gctgtaaaat ttttcctggt cacgtaagcg ccggaatcca
    17281 cttgcggcgg cgtgattttg acgctaaatt gaacgtcttg ctgataattt cagcacttga
    17341 gataaaaacg caaaaaaaac ttttttgggg ggttgcagag ggaaagattt ctcgtataat
    17401 gcgcctcccg taacgacgca gaaatgcgaa aattacgaaa gcaaaattaa gtagtacgcg
    17461 ggaatagctc agttggtaga gcacgacctt gccaaggtcg gggtcgcgag ttcgagtctc
    17521 gtttccc
//
LOCUS       DAPGUL010000093        17502 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.095, whole genome shotgun sequence.
ACCESSION   DAPGUL010000093 DAPGUL010000000
VERSION     DAPGUL010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17502
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.095"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(158..889)
                     /gene="rlmB"
                     /locus_tag="RHX21_003348"
     CDS             complement(158..889)
                     /gene="rlmB"
                     /locus_tag="RHX21_003348"
                     /EC_number="2.1.1.185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HDV1988494.1"
                     /translation="MSEMIYGIHAVQALLERAPERFQEVFILKGREDKRLLPLIHALE
                     SQGVVIQLANRQYLDEKSDGAVHQGIIARVKPGRQYQENDLPDLIASLDQPFLLILDG
                     VTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAESVPLIRVTNLART
                     MRMLQEENIWIVGTAGEADHTLYQSKMTGRLALVMGAEGEGMRRLTREHCDELISIPM
                     AGSVSSLNVSVATGICLFEAVRQRS"
     gene            complement(1069..3510)
                     /gene="rnr"
                     /locus_tag="RHX21_003349"
     CDS             complement(1069..3510)
                     /gene="rnr"
                     /locus_tag="RHX21_003349"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418600.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HDV1988495.1"
                     /translation="MSQDPFQEREAEKYANPIPSREFILEHLTKREKPASRDELAVEL
                     HIEGEEQLEGLRRRLRAMERDGQLVFTRRQCYALPERLDLVKGTVIGHRDGYGFLRVE
                     GRKDDLYLSSEQMKTCIHGDQVLAQPLGADRKGRREARIVRVLVPKTSQIVGRYFTEA
                     GVGFVVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAVGKIVEVLGDNM
                     GTGMAVDIALRTHEIPYIWPQAVEQQVAGLKEEVPEEAKAGRVDLRDLPLVTIDGEDA
                     RDFDDAVYCEKKRGGGWRLWVAIADVSYYVRPPTPLDREARNRGTSVYFPSQVIPMLP
                     EVLSNGLCSLNPQVDRLCMVCEMTVSSKGRLTGYKFYEAVMSSHARLTYTKVWHILQG
                     DQDLREQYAPLVKHLEELHNLYKVLDKAREERGGISFESEEAKFIFNAERRIERIEQT
                     QRNDAHKLIEECMILANISAARFVEKAKEPALFRIHDKPSTEAITSFRSVLAELGLEL
                     PGGNKPEPRDYAELLESVADRPDAEMLQTMLLRSMKQAIYDPENRGHFGLALQSYAHF
                     TSPIRRYPDLTLHRAIKYLLAKEQGHQGNTTETGGYHYSMEEMLQLGQHCSMAERRAD
                     EATRDVADWLKCDFMLDQVGNVFKGVISSVTGFGFFVRLDDLFIDGLVHVSSLDNDYY
                     RFDQVGQRLMGESSGQTYRLGDRVEVRVEAVNMDERKIDFSLISSERAPRNVGKTARE
                     KAKKGDAGKKGGKRRQVGKKVNFEPDSAFRGEKKTKPKAAKKDARKAKKPSAKTQKIA
                     AATKAKRAAKKKVAE"
     gene            complement(3549..3974)
                     /gene="nsrR"
                     /locus_tag="RHX21_003350"
     CDS             complement(3549..3974)
                     /gene="nsrR"
                     /locus_tag="RHX21_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide-sensing transcriptional repressor
                     NsrR"
                     /protein_id="HDV1988496.1"
                     /translation="MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVK
                     IINQLSRAGYVTAVRGKNGGIRLGKPASAIRIGDVVRELEPLSLVNCSSEFCHITPAC
                     RLKQALSKAVQSFLTELDNYTLADLVEENQPLYKLLLVE"
     gene            complement(4179..5477)
                     /gene="purA"
                     /locus_tag="RHX21_003351"
     CDS             complement(4179..5477)
                     /gene="purA"
                     /locus_tag="RHX21_003351"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019842885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HDV1988497.1"
                     /translation="MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTL
                     VINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSE
                     ACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAE
                     KLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDF
                     VMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGA
                     GPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLD
                     VLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGL
                     PQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA"
     gene            complement(5581..5778)
                     /locus_tag="RHX21_003352"
     CDS             complement(5581..5778)
                     /locus_tag="RHX21_003352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2065 domain-containing protein"
                     /protein_id="HDV1988498.1"
                     /translation="MNSTIWLALALVLVLEGLGPMLYPKAWKKMISAMTNLPDNILRR
                     FGGGLVVAGVVVYYMLRKTIG"
     gene            complement(5860..6864)
                     /gene="hflC"
                     /locus_tag="RHX21_003353"
     CDS             complement(5860..6864)
                     /gene="hflC"
                     /locus_tag="RHX21_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease modulator HflC"
                     /protein_id="HDV1988499.1"
                     /translation="MRKSVIAIIIIVLVVLYMSVFVVKEGERGITLRFGKVLRDDDNK
                     PLVYEPGLHFKIPFIETVKMLDARIQTMDNQADRFVTKEKKDLIVDSYIKWRISDFSR
                     YYLATGGGDISQAEVLLKRKFSDRLRSEIGRLDVKDIVTDSRGRLTLEVRDALNSGSA
                     GTEDEVTTPAADNAIAEAAERVTAETKGKVPVINPNSMAALGIEVVDVRIKQINLPTE
                     VSEAIYNRMRAEREAVARRHRSQGQEEAEKLRATADYEVTRTLAEAERQGRIMRGEGD
                     AEAAKLFADAFSKDPDFYAFIRSLRAYENSFSGNQDVMVMSPDSDFFRYMKTPTSATR
                     "
     gene            complement(6867..8126)
                     /gene="hflK"
                     /locus_tag="RHX21_003354"
     CDS             complement(6867..8126)
                     /gene="hflK"
                     /locus_tag="RHX21_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsH protease activity modulator HflK"
                     /protein_id="HDV1988500.1"
                     /translation="MAWNQPGNNGQDRDPWGSSKPGGNSEGNGNKGGRDQGPPDLDDI
                     FRKLSKKLGGLGGGKGTGSGGGSSSQGPRPQLGGRVVTIAAAAIVIIWAASGFYTIKE
                     AERGVVTRFGKFSHLVEPGLNWKPTFIDEVKPVNVEAVRELAASGVMLTSDENVVRVE
                     MNVQYRVTNPEKYLYSVTSPDDSLRQATDSALRGVIGKYTMDRILTEGRTVIRSDTQR
                     ELEETIRPYDMGITLLDVNFQAARPPEEVKAAFDDAIAARENEQQYIREAEAYTNEVQ
                     PRANGQAQRILEEARAYKAQTILEAQGEVARFAKLLPEYKAAPEITRERLYIETMEKV
                     LGNTRKVLVNDKGGNLMVLPLDQMLKGGNAPAAKSDNGASNLLRLPPASSSTTSGASN
                     TSSTSQGDIMDQRRANAQRNDYQRQGE"
     gene            complement(8212..9492)
                     /gene="hflX"
                     /locus_tag="RHX21_003355"
     CDS             complement(8212..9492)
                     /gene="hflX"
                     /locus_tag="RHX21_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDV1988501.1"
                     /translation="MFDRYDAGEQAVLVHIYFTQDKDMEDLQEFESLVSSAGVEALQV
                     ITGSRKAPHPKYFVGEGKAVEIAEAVKATGASVVLFDHALSPAQERNLERLCECRVID
                     RTGLILDIFAQRARTHEGKLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQL
                     ETDRRLLRNRIVQIQSRLERVEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNRIT
                     EARVYAADQLFATLDPTLRRIDVADVGETVLADTVGFIRHLPHDLVAAFKATLQETRQ
                     ATLLLHVIDAADVRVQENIEAVNTVLEEIDAHEIPTLLVMNKIDMLEDFEPRIDRDEE
                     NKPIRVWLSAQTGAGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKE
                     WMEEDGSVSLQVRMPIVDWRRLCKQEPALIDYLI"
     gene            complement(9568..9876)
                     /gene="hfq"
                     /locus_tag="RHX21_003356"
     CDS             complement(9568..9876)
                     /gene="hfq"
                     /locus_tag="RHX21_003356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HDV1988502.1"
                     /translation="MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVI
                     LLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGTSSNYHHGSSAQNTSAQQDSEETE
                     "
     gene            complement(9962..10912)
                     /gene="miaA"
                     /locus_tag="RHX21_003357"
     CDS             complement(9962..10912)
                     /gene="miaA"
                     /locus_tag="RHX21_003357"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HDV1988503.1"
                     /translation="MSDISKASLPKAIFLMGPTASGKTALAIELRKILPVELISVDSA
                     LIYKGMDIGTAKPNAEELLAAPHRLLDIRDPSQAYSAADFRRDALAEMADITAAGRIP
                     LLVGGTMLYFKALLEGLSPLPSADPEVRARIEQQAAEQGWESLHRQLQEVDPVAAARI
                     HPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIEQRF
                     HQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYLEGEISYDEMVYRGVCATR
                     QLAKRQITWLRGWEGVHWLDSEKPEQARDEVLQVVGAIAG"
     gene            complement(10905..12752)
                     /gene="mutL"
                     /locus_tag="RHX21_003358"
     CDS             complement(10905..12752)
                     /gene="mutL"
                     /locus_tag="RHX21_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HDV1988504.1"
                     /translation="MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDI
                     DIERGGAKLIRIRDNGCGIKKDELALALARHATSKIASLDDLEAIISLGFRGEALASI
                     SSVSRLTLTSRTAEQQEAWQAYAEGRDMNVTVKPAAHPVGTTLEVLDLFYNTPARRKF
                     LRTEKTEFNHIDEIIRRIALARFDVTINLSHNGKIVRQYRAVPEGGQKERRLGAICGT
                     AFLEQALAIEWQHGDLTLRGWVADPNHTTPALAEIQYCYVNGRMMRDRLINHAIRQAC
                     EDKLGADQQPAFVLYLEIDPHQVDVNVHPAKHEVRFHQSRLVHDFIYQGVLSVLQQQL
                     ETPLPLDDEPQPAPRAIPENRVAAGRNHFAEPAAREPVAPRYTPAPASGSRPAAPWPN
                     AQPGYQKQQGEVYRQLLQTPAPMQKPKAPEPQEPALAANSQSFGRVLTIVHSDCALLE
                     RDGNISLLALPVAERWLRQAQLTPGEAPVCAQPLLIPLRLKVSGEEKSALEKAQSALA
                     ELGIDFQSDAQHVTIRAVPLPLRQQNLQILIPELIGYLAKQSVFEPGNIAQWIARNLM
                     SEHAQWSMAQAITLLADVERLCPQLVKTPPGGLLQSVDLHPAIKALKDE"
     gene            complement(12762..14099)
                     /gene="amiB"
                     /locus_tag="RHX21_003359"
     CDS             complement(12762..14099)
                     /gene="amiB"
                     /locus_tag="RHX21_003359"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiB"
                     /protein_id="HDV1988505.1"
                     /translation="MMYRIRNWLVATLLLLCTPVGAATLSDIQVSNGNQQARITLSFI
                     GDPDYAFSHQSKRTVALDIKQTGVIQGLPLLFSGNNLVKAIRSGTPKDAQTLRLVVDL
                     TENGKTEAVKRQNGSNYTVVFTINADAPPPPPPPPVVAKRVETPAVVAPRVSEPARNP
                     FKTESNRTTGVISSNTVTRPAARATANTGDKIIIAIDAGHGGQDPGAIGPGGTREKNV
                     TIAIARKLRTLLNDDPMFKGVLTRDGDYFISVMGRSDVARKQNANFLVSIHADAAPNR
                     SATGASVWVLSNRRANSEMASWLEQHEKQSELLGGAGDVLANSQSDPYLSQAVLDLQF
                     GHSQRVGYDVATSMISQLQRIGEIHKRRPEHASLGVLRSPDIPSVLVETGFISNNSEE
                     RLLASDDYQQQLAEAIYKGLRNYFLAHPMQSAPQGATAQTASTVTTPDRTLPN"
     gene            complement(14118..14579)
                     /gene="tsaE"
                     /locus_tag="RHX21_003360"
     CDS             complement(14118..14579)
                     /gene="tsaE"
                     /locus_tag="RHX21_003360"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HDV1988506.1"
                     /translation="MMNRVIPLPDEQATLDLGERVAKACDGATVIYLYGDLGAGKTTF
                     SRGFLQALGHQGNVKSPTYTLVEPYTLDNLMVYHFDLYRLADPEELEFMGIRDYFAND
                     AICLVEWPQQGTGVLPDPDVEIHIDYQAQGREARVSAVSSAGELLLARLAG"
     gene            complement(14551..16098)
                     /gene="nnr"
                     /locus_tag="RHX21_003361"
     CDS             complement(14551..16098)
                     /gene="nnr"
                     /locus_tag="RHX21_003361"
                     /EC_number="4.2.1.136"
                     /EC_number="5.1.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HDV1988507.1"
                     /translation="MTDHTMKKNPVSIPHTVWYADDIRRGEREAADVLGLTLYELMLR
                     AGEAAFQVCRSAYPDARHWLVLCGHGNNGGDGYVVARLAKAVGIEVTLLAQESDKPLP
                     EEAALAREAWLNAGGEIHASNIVWPESVDLIVDALLGTGLRQAPRESISQLIDHANSH
                     PAPIVAVDIPSGLLAETGATPGAVINADHTITFIALKPGLLTGKARDVTGQLHFDSLG
                     LDSWLAGQETKIQRFSAEQLSHWLKPRRPTSHKGDHGRLVIIGGDHGTAGAIRMTGEA
                     ALRAGAGLVRVLTRSENIAPLLTARPELMVHELTMDSLTESLEWADVVVIGPGLGQQE
                     WGKKALQKVENFRKPMLWDADALNLLAINPDKRHNRVITPHPGEAARLLGCSVAEIER
                     DRLHCAKRLVQRYGGVAVLKGAGTVVAAHPDALGIIDAGNAGMASGGMGDVLSGIIGA
                     LLGQKLSPYDAACAGCVAHGAAADVLAARFGTRGMLATDLFSTLQRIVNPEVTDKNHD
                     ESSNSAP"
     gene            16097..17236
                     /gene="queG"
                     /locus_tag="RHX21_003362"
     CDS             16097..17236
                     /gene="queG"
                     /locus_tag="RHX21_003362"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HDV1988508.1"
                     /translation="MSEPLDLNQLAQKIKQWGLELGFQQVGITDTDLSESEPKLQAWL
                     DKQYHGEMDWMARHGMLRARPHELLPGTLRVISVRMNYLPANAAFASTLKNPKLGYVS
                     RYALGRDYHKLLRNRLKKLGEMIQQHCVSLNFRPFVDSAPILERPLAEKAGLGWTGKH
                     SLILNREAGSFFFLGELLVDIPLPVDQPVEEGCGKCVACMTICPTGAIVEPYTVDARR
                     CISYLTIELEGAIPEELRPLMGNRIYGCDDCQLICPWNRYSQLTTEEDFSPRKPLHAP
                     ELIELFAWSEEKFLKVTEGSAIRRIGHLRWLRNIAVALGNAPWDETILTALESRKGEH
                     PLLDEHIAWAIAQQIERRNACIVEVQLPKKQRLVRVIEKGLPRDA"
     gene            complement(17219..17272)
                     /locus_tag="RHX21_003363"
     CDS             complement(17219..17272)
                     /locus_tag="RHX21_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988509.1"
                     /translation="MRFYFYSQAVDESGVTR"
BASE COUNT         3981 a         4988 c         4381 g         4152 t
ORIGIN      
        1 ccgtcgccag cgccaacgga ttccatgtca tatattattc catatagatt tagtttaaat
       61 attaataaaa tgaatatttg cagtacgtaa ttatcttacc agctatagac aaaaaaaaac
      121 catccaaatc tggatggctt ttcataattc agacgaacta gctgcgctga cgaaccgctt
      181 caaataagca aattccggtt gcaaccgaaa cgttcaggga agaaacactt cctgccattg
      241 ggatgctgat caactcatcg caatgttcac gggtcaggcg acgcatacct tcaccttccg
      301 cgcccatcac cagcgccagg cgtccggtca ttttgctctg atagagtgta tgatccgcct
      361 cgcctgccgt accgacgatc cagatattct cttcctgcaa catacgcatg gtgcgcgcaa
      421 ggttagtcac ccgaatcagt ggaacgcttt ctgccgcgcc gcaggctact tttttcgccg
      481 tagcgttgag ctgtgcggag cgatctttcg gcacaatcac cgcgtgaacg ccagcagcgt
      541 ccgcgctacg caggcacgcg ccgaggttgt gcggatcggt tacaccgtcg aggatcagca
      601 ggaacggttg atcgagcgaa gcgatcagat ccggcagatc gttttcctga tactgacgtc
      661 ctggcttcac gcgggcgata atgccctgat gcacggcacc gtcgcttttc tcgtcgagat
      721 attggcggtt tgccaactgg ataaccacgc cctgagactc aagggcgtga atcagcggta
      781 acagacgttt atcttcacgg ccttttaaaa taaagacttc ctgaaaacgt tcaggggcgc
      841 gctccagcag ggcctgcact gcgtggatgc cgtaaatcat ttcgctcatt aatgtactcg
      901 ttgtttacgt tttgcctgat gcactacgtt tatccggcct acatgatctc tgcaatatat
      961 tgaatttgcg tgattatgta ggccggataa ggcgttcacg ccgcatccgg catgaacaaa
     1021 gcgcattttg tcagcaatct aaccctcttc ttttaaagag ggtattgatc actctgccac
     1081 ttttttcttc gccgcacgct tcgctttggt cgctgcggct attttctgcg ttttcgccga
     1141 tggctttttc gcttttctcg cgtctttctt cgccgctttc ggcttcgttt ttttctcacc
     1201 gcggaaggcg ctgtctggct caaagtttac ctttttaccg acctgacgac gcttgccgcc
     1261 ttttttgcct gcatcgcctt ttttcgcttt ctcgcgcgcc gttttaccga cgttgcgcgg
     1321 tgcgcgttca ctggagatca gactaaagtc gattttgcgc tcgtccatat taaccgcttc
     1381 gacgcgaact tccacgcgat cgcccaggcg ataagtctgg ccgctggatt cccccatcag
     1441 gcgttgccct acctggtcaa agcgatagta gtcattgtcc agcgaagaga catggaccag
     1501 accatcaatg aacaagtcgt ccagacggac gaagaagcca aagccagtga cgctggaaat
     1561 tacgccttta aagacgttac ctacctggtc gagcatgaag tcacacttca gccagtcagc
     1621 gacatcgcgc gttgcttcgt cggcacgacg ttccgccatc gaacagtgct gacccagttg
     1681 caacatctct tccatcgaat aatggtagcc gccggtttca gtggtgttgc cctgatgccc
     1741 ctgctctttc gccagcagat atttaatggc gcggtgcagc gtcaggtcag gataacgacg
     1801 aatcggcgaa gtaaagtgcg cataggactg caatgccaga ccgaagtgac cacggttttc
     1861 tggatcgtaa atcgcctgtt tcatcgagcg tagcagcatg gtttgcagca tttctgcatc
     1921 aggacggtcg gcaaccgact ccagcagttc cgcgtagtca cgcggttccg gcttgttacc
     1981 acccggcagc tccagcccca gctccgccag cactgaacgg aaagaggtaa tcgcttcggt
     2041 gctcggcttg tcgtgaatac ggaacagtgc cggttctttc gctttctcaa cgaaacgcgc
     2101 cgccgagata ttcgccagaa tcatgcactc ttcaattaat ttgtgcgcgt cgttacgctg
     2161 ggtctgttcg atacgttcaa tacggcgttc agcgttgaaa atgaacttcg cttcttcgct
     2221 ctcaaatgag atcccaccgc gttcttcacg ggctttatcc agcactttat agaggttatg
     2281 caactcttcg agatgcttaa ccagcggggc gtactgctcg cgcagatcct gatcgccctg
     2341 cagaatatgc cagactttgg tgtaggtcag acgcgcgtga gagctcatca ccgcttcgta
     2401 gaatttgtag cccgtcaggc ggcctttcga cgaaaccgtc atctcgcaca ccatacacag
     2461 gcggtctacc tgcgggttga gcgagcacag gccgttagag agcacttccg gcagcatcgg
     2521 gataacctgc gaagggaagt acaccgacgt accacgatta cgcgcttctc tgtccagcgg
     2581 cgttggcgga cgcacatagt agctgacgtc ggcaatcgcg acccataaac gccagccgcc
     2641 gccgcgtttt ttctcgcagt aaactgcatc gtcaaagtca cgggcgtctt cgccatcaat
     2701 ggtgaccagc ggtaaatcgc gcaaatcgac acggcccgct tttgcttctt ccggcacttc
     2761 ttctttcagc ccggcaacct gttgctcaac agcctgcggc cagatgtacg gaatttcatg
     2821 ggtacgcaga gcgatatcaa ccgccatgcc ggtgcccata ttatcgccaa ggacttcgac
     2881 gattttaccc accgctttgg tacggcgagt cgggcgttgg gtcagttcaa caaccaccac
     2941 aaagcccatc cgcgcgccca tgatctgatc gggcgggatt aagatatcga agctcagacg
     3001 gctgtcgtca ggaaccacaa agccgacgcc cgcttcggta aagtagcgac caacaatctg
     3061 gctggttttt ggcaccagta cacggacaat acgcgcttca cgacgacctt tacggtcagc
     3121 gcccagcggc tgcgccagca cctgatcgcc atgaatgcag gttttcatct gctcgctgga
     3181 gagatacaaa tcatctttac gcccttcaac ccgcagaaag ccgtagccat cacggtggcc
     3241 aataacggta cctttcacca ggtcgaggcg ttccggcagc gcatagcact gacgacgagt
     3301 gaagaccagt tgaccatcgc gctccatcgc gcgcaggcgg cgacgcaggc cttcaagctg
     3361 ctcttcgcct tcaatgtgca gttctaccgc cagctcatca cggctggccg gtttttcacg
     3421 tttggttaaa tgttcgagga taaattcccg actagggatg ggattcgcgt atttttcagc
     3481 ttcgcgttcc tggaaaggat cttgtgacat ctcggttcct ccgttgtcat ctctgatgaa
     3541 gattttcgtc actccaccag caataattta taaagcggtt gattctcttc aaccaaatcg
     3601 gcaagcgtgt agttatccag ttccgtaaga aaactttgca cggccttaga aagcgcctgt
     3661 ttcaaccgac aggcaggtgt aatgtggcaa aactcactgc tgcaattcac cagcgataag
     3721 ggctccagct cgcgcaccac atcaccaata cgtatcgcac tcgccggttt acccaggcga
     3781 atgccgccat tttttccacg aacagcagtc acgtagccgg cacgactaag ttgattgatt
     3841 attttgacca tatgattacg ggagacgccg tagacgtcag tcacttcaga aatactggtc
     3901 atccgccctt ctggcaatga cgccatgtag atcagcgcac gtaatccgta atcagtgaaa
     3961 ctcgttaact gcacatcaac ctcaaaaggg aaatcgggaa aaaatacatt tatattgatg
     4021 ataaaccagc cacaagctgt gtcgctaatt tatttcagtt cggggaagga aaaaagcgag
     4081 gatttaacac tgtgtcggat agcgtaatgg cttaaccgac acagcaatgt atcacactgt
     4141 tagcccggca ggcaaaatat ctgccaggcg taccagaatt acgcgtcgaa cggatcgcgc
     4201 agaatcatgg tttcagtacg atccggaccg gtagagatga tatcgatcgg cacaccagtc
     4261 agctcttcaa tacgcttgat gtagttcagc gccgcctgcg gcagaccgct acgatctttc
     4321 acgccgaagg tggattcaga ccagcccggc atggtttcgt aaatcggctc tacacctttc
     4381 cagtcgtcag ctgccagcgg agtggtagtc acttcgcgac catccggcat acggtaagcc
     4441 acgcagagtt taacctcttt caggccatcc agaacgtcca gtttagtcag gcagaagcca
     4501 gacagggagt tcagctgtac cgcacgacga acggcaacgg tgtccagcca gccggtacga
     4561 cgacgacgcc ccgtagttgc gccgaattcg ttaccctgct tgcagaggaa ctcgccagtt
     4621 tcatcaaaca gttcggtcgg gaacggacct gcacctacac gagtggagta agctttgagg
     4681 atacccagaa cgtaatcaac ataacgcggg cccaggccgg aaccggtcgc cacgccacca
     4741 gcagtggtgt tggaagaagt tacgtacgga taagtaccgt ggtcgatatc cagcagcgta
     4801 ccctgcgcac cttcaaacat gacgaaatcg ccacgctgac gcgcctggtc gagcaggtca
     4861 gaaacgtcaa ccaccataga agtcaggatg tcggcaacag ccatcgtatc atccagaact
     4921 ttctggtaat caaccgcttc agctttgtag tagttaacca actggaagtt gtgatattcc
     4981 atcacttctt tcagtttttc agcgaaggtt tctttgtcga aaaggtcgcc aacacgcaga
     5041 ccgcgacgtg ctactttatc ttcataagca ggcccgatac cacgaccggt ggtgccgatc
     5101 gctttcgcgc cacgcgcttt ctcacgcgcg ttatccagcg caacgtgata atcaaggatc
     5161 agcggacatg cttcagacag cagcagacgc tcacgaacgg ggatgccacg gtcttccagt
     5221 tctttcatct ctttcatcag cgcggccgga gacagcacaa caccgttacc gatgatgctg
     5281 gttacattct cgcggagaat acctgatgga ataagatgga gaacggtttt ttcaccgttg
     5341 attacgagag tatggcctgc gttgtgaccg ccctggtagc gtacaacata tttagcccgt
     5401 tcagtcagaa gatcgacgat cttaccttta ccttcgtcac cccattgggt gcccagtacg
     5461 acgacgttgt tacccatttt tcaaaatcac cgtttgctta aaaatggatt ctaccatcgc
     5521 tttttcagag ttacagcact ttttgcactc aaaaatgacc tcgatcagtc tgttttttgt
     5581 tcagccaatc gttttcctca acatgtagta gaccacaacg cccgcaacca caagtccacc
     5641 gccaaaacga cgtaaaatat tatcgggcaa attggtcatc gcagagatca tcttcttcca
     5701 tgccttcggg taaagcatcg gccctaaacc ttccagtacc aaaaccaggg caagcgccag
     5761 ccagattgtc gaattcattc attatcctta tagaaaaaga aaaccaccga catccctgag
     5821 gatgcggtgg ctttattgac ctgtaccgca gtcgttatat taacgcgttg cggaagtcgg
     5881 cgtcttcatg tagcggaaga aatcgctatc cgggctcatg accatcacgt cctgattgcc
     5941 agagaagctg ttctcataag cacgcaggct acggatgaat gcgtagaagt ccggatcttt
     6001 actgaatgca tcagcaaaca gtttggctgc ttcggcatcg ccttcaccac gcatgatgcg
     6061 gccctgacgc tcagcttctg ccagcgttct ggtcacttca tagtcggcag tcgcgcgcag
     6121 tttttccgct tcttcctgac cttgtgaacg gtgacgacgc gctaccgctt cacgctcggc
     6181 gcgcatacgg ttgtagatcg cttcagacac ttcggtcggc aggttgatct gcttgatacg
     6241 cacatcgaca acttcaatac ccagcgccgc catactgttc gggttgatga ccggaacttt
     6301 gcccttcgtc tcagccgtta cgcgctctgc cgcttcggca atggcgttat ccgctgccgg
     6361 ggtagtaact tcatcttctg tacccgcaga accggagttc agcgcgtcac gtacttcgag
     6421 ggtcagacga ccacgggaat cggtgacgat gtctttcacg tccaggcgac caatttcaga
     6481 acgcagacgg tcagagaact tacgtttcaa cagcacttcc gcttgcgaaa tgtcgccacc
     6541 acccgttgcc aggtagtaac ggctgaaatc gctgatgcgc catttgatgt aagagtcgac
     6601 gatcaggtct ttcttctctt tggtcacaaa gcggtcggcc tggttgtcca tggtctgaat
     6661 acgtgcgtcg agcattttca ccgtttcaat gaacggtatc ttgaaatgca gacccggctc
     6721 ataaaccaga ggtttgttgt catcgtcacg cagtacctta ccaaaacgca gcgtaatacc
     6781 gcgctcacct tctttgacga caaagacaga catgtaaagc actaccagca cgatgatgat
     6841 aatcgcgata actgacttac gcatcgttat tccccctgac gctggtagtc gttacgctgc
     6901 gcgttggcgc ggcgttggtc cataatatcg ccctgactgg tggacgacgt gttgcttgct
     6961 ccactggttg tggaggaaga ggctggcggc aaacgcagca gattgctggc accgttatcg
     7021 ctcttcgccg caggggcgtt accacctttc agcatctggt ctaacggcag aaccatcagg
     7081 ttgccacctt tatcgttaac cagcactttg cgggtgttac ccaacacttt ttccatcgtc
     7141 tcgatataca gacgctcgcg agtaatttcc ggcgcggctt tatattccgg cagaagttta
     7201 gcaaagcgcg ccacttcacc ctgagcttcc aggatggtct gggccttgta cgcacgcgcc
     7261 tcttcgagga tacgttgcgc ctgaccgttc gcacgcggct gaacttcgtt ggtatacgct
     7321 tctgcttcac gaatgtattg ctgttcgttt tcacgcgcgg caatcgcatc gtcaaacgcc
     7381 gcttttactt cttccggcgg acgagcagcc tggaagttga cgtccagcag cgtgataccc
     7441 atgtcatacg gacggatagt ctcttccagt tcgcgctgag tatcgctacg aatcacggta
     7501 cgaccttccg tcagaatgcg gtccatggtg tatttaccga taaccccgcg cagggcgctg
     7561 tcggtagcct gacgcagact gtcatccggg ctggtcacgc tatacagata tttttccgga
     7621 ttggtaacgc ggtactgcac gttcatctca acgcgcacta cgttctcgtc cgacgtcaac
     7681 atcacaccgg aagcggccag ttcacgcacg gcttccacgt ttaccggttt gacttcgtcg
     7741 ataaacgtcg gtttccagtt cagacccggc tcaaccagat ggctgaattt accaaagcgt
     7801 gttaccacgc cgcgttcggc ttctttaatg gtatagaaac cactggccgc ccagataatg
     7861 acaatcgctg ccgctgcgat ggtaacgaca cgaccgccaa gctgcgggcg cgggccttgc
     7921 gatgaactgc caccgccaga tccggtgcct ttaccgccgc ccagaccacc gagctttttg
     7981 ctcagtttgc ggaagatatc atctaaatca ggtggccctt gatcgcgacc gcctttgttt
     8041 ccatttccct cagagttgcc gccaggtttg ctgcttcccc acgggtcgcg gtcttgtccg
     8101 ttattaccgg gctgattcca cgccatgttt gtgctccata tttgttatgc ggtgatccct
     8161 gttgtctttc gacgccagag gatatgactc cacgcttcag acgctacgcc gttagatcag
     8221 gtaatcgatc aacgccggtt cttgtttaca gaggcgacgc cagtcaacga tcggcatacg
     8281 aacttgcaga cttacgctgc cgtcctcctc catccactct ttttctattg cctgaagctg
     8341 ataaaaacga cttctcagac gcccttcctg cggtggcaga cgcaatgtat gctgcgccac
     8401 ctcgccggaa agccgctccg tcaaagcctg aaaaagctgt ggtatccccg ctccggtctg
     8461 tgcggaaagc cagacacgga tcggtttgtt ctcttcgtcc cgatcaatac gcggttcgaa
     8521 atcttccagc atatcgatct tgttcatcac cagcagggtt gggatctcgt gagcgtcgat
     8581 ctcttcaaga accgtattca ccgcttcgat gttttcttgt acacgcacat ccgccgcatc
     8641 aatgacgtgc agcagtaatg tggcttgccg cgtctcttgt aacgtggctt taaatgctgc
     8701 aaccagatcg tgcggcaggt ggcgaataaa ccctacggta tctgccaaca cggtttcacc
     8761 gacatctgca acgtcaatac gccgcaacgt cgggtcgagg gtggcaaaca actggtctgc
     8821 cgcgtagacc cgcgcttcgg tgatgcgatt gaaaagggta gatttaccgg cgttggtata
     8881 tcccaccagc gaaacagtag gaacgtcggc tttgatacgc gattgccgcc cctgctcacg
     8941 ctgcttttca actctttcca ggcgcgactg tatctgcacg atgcgattac gcaacaaacg
     9001 acggtcggtt tcgagctggg tttcacccgg accacgcaaa cctatcccgc ctttctgtct
     9061 ttcaaggtgg gtccagccac gcaccaggcg cgtagccaga tggcgcagct gcgccagctc
     9121 aacctgcaac ttaccctcat gggtacgcgc acgttgggcg aaaatatcta aaataaggcc
     9181 ggtgcggtcg ataacacgac actcgcacaa acgctccagg ttacgctctt gcgccgggct
     9241 cagggcatgg tcaaaaagaa cgaccgaagc acccgtcgct ttgacagctt ccgcaatttc
     9301 aactgcttta ccttcaccta caaaatactt tgggtgcggc gctttacggc taccggtaat
     9361 cacctgcaat gcttcgacac cggcggaaga gaccagagat tcaaactcct ggaggtcttc
     9421 catatctttg tcttgcgtaa aatagatgtg taccagtacc gcctgctcac cagcatcata
     9481 acggtcaaac aagcgtataa ccctctaaat agatcagcgg ggaacgcagg atcgctggct
     9541 ccccgtgtaa aaaaacagcc cgaaacctta ttcggtttct tcgctgtcct gttgcgcgga
     9601 agtattctgc gcgctgctac catgatggta gttactgctg gtaccgccac cggcgttgtt
     9661 actgtgatga gaaaccggac gagacgggac aacagtagaa atcgcgtgct tgtaaaccat
     9721 ctggctgacc gtgtttttca acaggatcac gaactgatca aaagactcga tttgcccttg
     9781 cagcttaata ccattcacca aataaataga aactggaaca cgttcccgac gcagtgcgtt
     9841 caggaacgga tcttgtaaag attgcccctt agccattctc tcttttcctt atatgcttat
     9901 ttgtactttg aacctttcga ttctgaaaaa attgcgcacg atacgtctca attgtacaca
     9961 ttcagcctgc gatagcacca acaacctgta atacttcgtc acgcgcctgt tctggttttt
    10021 cactgtcaag ccagtgaacc ccttcccaac cacgcagcca ggttatctgc cgcttcgcca
    10081 actgtctcgt ggcgcaaaca cctcgataaa ccatttcatc gtatgagatt tcgccttcaa
    10141 ggtaagacca catctggcga taacccacgc aacgaatgga aggcaagtcc gtatgcaaat
    10201 ctcctcgggc aaaaagcgcc cggacttctg cttcaaaacc tgaagccaac atctgatgaa
    10261 aacgctgctc aatgcgttga tggagcagtt cacggctcgc cggggcgatg gcgaactgat
    10321 gcacctgata cggtagagcg tctcctgacg tttgcgtcag ttccgttaaa gttttacccg
    10381 aaatgaaaaa aacttccagt gcccgggaaa gcctttgtgg atcatttgga tgaatccttg
    10441 ctgccgcaac cggatctacc tcctgaagtt gacgatgcaa tgactcccaa ccttgctctg
    10501 ccgcctgttg ctcaattctg gcccgcactt ccgggtctgc cgacggtagc ggcgacaacc
    10561 cttccagcaa tgccttgaaa tacaacatcg taccgcccac taacagtggg atccgccccg
    10621 ccgcggtgat atcggccatt tccgccagcg catcgcggcg aaaatcagca gccgagtaag
    10681 cctgcgacgg atcgcgaata tccagcaatc ggtgcggcgc ggcgagtaac tcttcagcgt
    10741 tcggcttcgc cgtcccgata tccatccctt tgtaaataag ggcagaatca acgcttatca
    10801 actctactgg taaaatttta cgcagctcaa tggctaacgc cgttttaccg gaggccgtcg
    10861 gccccatcaa aaaaatcgcc ttaggcaggc tcgccttact gatatcactc atctttcagg
    10921 gcttttatcg ccggatgtaa atcaacagat tgtaacagac cacccggcgg cgttttcaca
    10981 agttgcggac ataaccgttc cacgtccgcc agcagggtta tggcctgtgc cattgaccac
    11041 tgcgcatgtt cgctcatcag atttcgtgca atccactgcg caatattgcc aggttcgaat
    11101 acggactgct tcgccaggta gcctatcagt tcaggaatca agatttgtaa attttgttgg
    11161 cgtaagggta aaggcacggc cctgatggtc acatgctgtg catctgactg gaaatcaata
    11221 cccaattccg ccagggcaga ctgcgctttt tctaatgccg atttttcttc gccagaaact
    11281 tttagccgca acggaatcag caacggctgg gcgcaaactg gcgcttcacc cggcgtcagt
    11341 tgcgcctgac gcagccaacg ttctgccact ggcaaggcta aaagtgaaat gttgccgtcg
    11401 cgctccagca acgcacagtc ggaatggacg atagtcagta cccgaccaaa actctgactg
    11461 ttcgccgcaa gtgcaggttc ctgcggttcc ggcgcttttg gtttttgcat cggcgcgggc
    11521 gtttgcaaaa gctggcgata cacttcacct tgctgtttct ggtagcctgg ctgcgcattc
    11581 ggccaggggg cagccggacg actgcctgat gctggcgcag gagtgtaacg cggagctacc
    11641 ggctcccgag ctgccggttc tgcaaagtga ttgcgccccg ccgccacgcg gttttccggg
    11701 atggcacgcg gtgcaggttg gggttcatcg tccagcggta gcggcgtttc cagttgctgc
    11761 tgtaacacgc tcagcacgcc ttgatagata aagtcatgca ccagacgcga ctgatgaaaa
    11821 cgcacttcgt gtttggcggg gtgcacgttg acgtccacct gatgtgggtc gatctccaga
    11881 tacagcacaa atgccggttg ctgatcggcc cccagtttgt cttcgcaggc ctggcggatc
    11941 gcgtgattga tcaggcgatc gcgcatcatg cgaccgttca cgtagcaata ctgaatttct
    12001 gccagtgcgg gcgtggtgtg atttggatcg gccacccagc cgcgtagcgt gagatcgccg
    12061 tgttgccatt caatcgccag cgcttgttca agaaaagcgg tgccgcaaat cgcgcctaag
    12121 cgccgttctt tttgcccgcc ttccggcact gcgcggtact gacgcacaat tttaccgtta
    12181 tgcgacaggt tgatcgtgac gtcgaaacgc gccagcgcaa tgcggcggat gatctcatca
    12241 atgtggttaa attcggtttt ctcggtgcgc aggaatttgc gccgcgccgg ggtgttgtag
    12301 aacagatcca gcacctccag cgtcgtcccc acaggatgcg ccgccggttt taccgtcacg
    12361 ttcatatcgc gcccttcggc ataggcctgc caggcttcct gctgttctgc ggtgcgtgaa
    12421 gtgagcgtca ggcgggaaac cgaactgata ctcgccagcg cctcaccgcg aaagcccagg
    12481 ctgataatgg cttcgagatc gtccagagag gcgattttac tggtggcatg acgcgccagc
    12541 gccagcgcca gctcatcttt tttgataccg cagccgttat cacgaatgcg gataagtttc
    12601 gccccaccgc gttcgatatc aatatcgata cgcgtcgcgc ctgcatcgag gctgttttcc
    12661 accagttctt tgactaccga cgcaggtcgc tcgaccacct cacctgcggc aatctggttc
    12721 gccagttgtg gcggtaagac ctgaattggc atcaatcgtc cttagtttgg cagcgtgcga
    12781 tctggcgtcg tcaccgtact ggcagtttgt gccgttgccc cctgcggcgc agattgcatc
    12841 ggatgcgcaa ggaaataatt gcgcaggcct ttgtaaatgg cttctgccag ctgttgttgg
    12901 taatcgtcgc tcgccagcaa acgttcttcg ctgttgttgc tgataaaacc ggtttcgacc
    12961 agtactgacg ggatatccgg cgaacgcaga acgccgagac tcgcgtgttc tggtcggcgt
    13021 ttatgtattt cgccaatgcg ttgcaactga ctgatcatac tggtcgctac atcataccct
    13081 acccgttggg aatgaccgaa ctgtaaatcc agcaccgcct ggcttaaata ggggtcagac
    13141 tgactgttcg ccagcacatc acccgcccca cccagcagct ccgactgttt ctcgtgctgc
    13201 tccagccagc tggccatttc gctgttggcg cgacggttag agagcaccca tacggaagcg
    13261 ccagtcgcac tgcggttcgg tgcggcatca gcgtgaatcg acacgaggaa attggcgttt
    13321 tgcttacgtg ccacatcact gcgccccatc accgagataa agtaatcccc gtcacgggtt
    13381 aaaacgccct taaacatcgg atcgtcattg agcaaagtac gcaatttacg cgcgatggcg
    13441 atggtgacat ttttctcccg cgtaccaccg gggccgatag cgccagggtc ctgaccgccg
    13501 tgtccggcat caatagcgat gataatttta tcgccagtgt tagccgtcgc gcgcgctgcc
    13561 ggacgcgtta ccgtattact gctgataaca cccgtagtgc ggttactttc cgttttaaac
    13621 ggattgcgcg ccggttcgct gacgcgcggt gcgacaaccg caggcgtttc aacgcgtttc
    13681 gcaaccacgg gcggcggagg aggaggtggc ggcgcatcgg cgttaatcgt aaagacgaca
    13741 gtgtaattgc tgccattctg ccgcttcacc gcttcggttt taccgttttc ggtaagatcg
    13801 accaccagcc gtagcgtttg tgcatcttta ggcgttccag agcgaatcgc cttcaccaga
    13861 ttattgccgc tgaacaacaa cggcagtccc tgaatcacgc ccgtttgttt gatatcgagc
    13921 gccacggtgc gtttgctttg atggctaaac gcataatcag gatcgccaat aaaactcaac
    13981 gttatccgcg cctgttgatt accgttagaa acctgaatat cagagagcgt cgcggcaccc
    14041 accggcgtgc acagcagcag cagcgtcgct accaaccaat ttctgatgcg atacatcatc
    14101 ccgccacctt tcaaaggtta accggctaaa cgcgccagca acaattcacc cgcagaggaa
    14161 accgcactca cgcgcgcctc acggccttgt gcctgataat caatgtgtat ttcgacatcc
    14221 gggtcaggaa gaacaccagt accttgttgt ggccactcca ccaggcagat ggcatcgttg
    14281 gcaaaataat cgcgaatccc cataaactcc agctcctcgg gatcggcaag gcggtacaaa
    14341 tcaaagtgat aaaccattaa attgtcgagc gtatagggtt cgaccagcgt ataagtgggg
    14401 cttttgacat taccctgatg acccagagct tgtaaaaagc cccggctaaa ggtggtttta
    14461 cctgcgccta aatcgccata cagatagatt acggttgcgc catcgcaggc tttcgctacc
    14521 cgctcgccca ggtctaatgt tgcctgctca tcagggagcg gaattactcg attcatcatg
    14581 gtttttatca gtcacttccg ggttaacaat acgctgtagc gtggaaaaga gatcggttgc
    14641 cagcatcccg cgcgttccaa aacgcgccgc cagtacgtca gctgcagcac cgtgcgcgac
    14701 acagcccgca caggcggcat catacggcga cagtttttgc ccaagcaatg cgccaataat
    14761 accagagagc acatcgccca tgccgccgct cgccatgcct gcatttccgg catcaataat
    14821 gcctaaagcg tcaggatggg cggcgaccac ggttccggca cctttcagca ccgctacgcc
    14881 gccataacgt tgtaccagac gtttggcgca atgtaagcgg tcacgttcaa tttcagcgac
    14941 ggaacagcct aacaaccgtg cggcctcgcc aggatgcggc gtgatcacgc gattgtgacg
    15001 cttatcggga ttgattgcca gcaggttcaa tgcatcggca tcccacaaca tcggtttgcg
    15061 aaaattctca actttttgca gtgctttttt cccccactct tgctggccca gaccgggacc
    15121 aatcaccacc acatcggccc attccaggct ttcggtaaga gagtccatcg tcagttcatg
    15181 caccatcaat tccggtcgtg cagtcagcag cggcgcaatg ttttcactgc gggtcagtac
    15241 tcggactaaa ccagcaccag cacgtagcgc cgcttccccc gtcatacgaa tagcccccgc
    15301 cgtgccgtga tcgccaccga taattaccag ccgcccgtga tcgcctttat gcgaagtcgg
    15361 gcgacgcggt tttagccagt gagaaagttg ttctgccgaa aaccgctgaa ttttcgtctc
    15421 ctgacctgcc agccaactat ccagccccag tgagtcaaaa tgcagttgtc cggtaacatc
    15481 ccgcgctttt ccagtgagca agcctggttt cagcgcaata aaagtgatgg tgtgatcggc
    15541 gttgatcacc gcgcctggcg tagcgccagt ttcagccagc aggccggaag ggatatcaac
    15601 cgccacaatc ggcgcaggat gggaattagc gtggtcgatt aactggctaa tggattcgcg
    15661 gggcgcttgc cgcaaaccgg taccgagcag cgcatcaaca atcagatcta ccgattcggg
    15721 ccagacaata ttcgaagcat ggatctcgcc acccgcgttt aaccatgctt cgcgtgccag
    15781 cgcggcctct tccggcaacg gtttgtcgct ctcctgggcc aacaacgtga cctcaatgcc
    15841 gaccgctttg gccagtcgcg cgaccacgta gccatcgccg ccgttattac catgaccgca
    15901 cagcaccagc cagtggcggg cgtcaggata cgccgaacga cacacctgga atgcggcctc
    15961 gccagcgcga agcatcagct catagagtgt gagccccagc acatctgccg cctcgcgttc
    16021 tccgcggcgg atatcgtcgg cgtaccagac ggtgtgtggt atacttacgg ggtttttctt
    16081 cattgtatgg tccgtcatgt cagagcccct cgatctcaat cagttagcgc aaaaaattaa
    16141 acagtgggga ctggaactgg gctttcagca ggtaggtatt accgataccg atctcagcga
    16201 gtccgagccc aaactgcaag catggctgga caaacaatac cacggcgaaa tggactggat
    16261 ggcacgtcac ggtatgctgc gcgctcgccc ccatgagtta ttgcccggta cgctgcgcgt
    16321 gatcagcgtg cggatgaatt accttcctgc taacgccgca tttgccagca cgctgaaaaa
    16381 ccccaaactc ggctatgtta gccgttatgc gctgggccgt gactatcaca aacttctgcg
    16441 caaccgactc aaaaagctgg gcgagatgat tcagcaacat tgtgtttcgc tgaattttag
    16501 accgtttgtc gattctgcgc ctattctcga gcgcccgtta gctgaaaaag ctgggctcgg
    16561 ctggacaggt aagcactcac ttatcctcaa tcgcgaggcc ggttctttct tctttttagg
    16621 cgaattgctg gtcgatattc cgctgcccgt ggatcaacca gtcgaggaag gatgcggtaa
    16681 atgcgtggcc tgtatgacga tttgcccgac cggtgccatc gtcgagccat ataccgtcga
    16741 tgctcgccgc tgtatctctt atctcaccat cgaacttgaa ggggcgatcc cggaagagtt
    16801 gcgaccgtta atgggaaacc gtatttacgg ttgcgatgac tgccagctta tctgcccgtg
    16861 gaatcgctat tcacaactca ccacagaaga ggatttcagc ccgcgtaagc cgctacacgc
    16921 accggaactc attgagttat tcgcctggag cgaagagaag tttttaaaag tcacggaagg
    16981 atcggcgatt cgtcgtattg gtcacctgcg ttggctgcgt aatatcgccg tagcattagg
    17041 caatgcccct tgggatgaaa cgattttgac agcgctggaa agtcgtaaag gtgagcaccc
    17101 acttctcgat gagcacatag cgtgggcgat tgcgcagcaa atagagagac gaaatgcgtg
    17161 catagtcgaa gtgcaattgc cgaaaaaaca gcgtctggtt cgggtgattg aaaaagggtt
    17221 accgcgtgac gcctgattca tccacagctt gtgaataaaa ataaaaacgc attgcaattc
    17281 aagacgaata aaatcgtcaa gtgatcgact cgacaaaacg gaatcttaat ttttaactta
    17341 tctatcaata ggttaaaaaa atactattca ccgtgcgaag tttctttgaa attaagatta
    17401 cagcctgagg ctgtggataa ctctgtttac aagagtttgt cagagacaac gaaaaccagc
    17461 aataacgcat cgcatcgctg tggatatttt attgagagaa ga
//
LOCUS       DAPGUL010000094        17387 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.096, whole genome shotgun sequence.
ACCESSION   DAPGUL010000094 DAPGUL010000000
VERSION     DAPGUL010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17387
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.096"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(13..1296)
                     /gene="gltA"
                     /locus_tag="RHX21_003364"
     CDS             complement(13..1296)
                     /gene="gltA"
                     /locus_tag="RHX21_003364"
                     /EC_number="2.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (Si)-synthase"
                     /protein_id="HDV1988510.1"
                     /translation="MADTKAKLTLNGDTAVELDVLKGTLGQDVIDIRTLGSKGVFTFD
                     PGFTSTASCESKITFIDGDEGILLHRGFPIDQLATDSNYLEVCYILLNGEKPTQEQYD
                     EFKTTVTRHTMIHEQITRLFHAFRRDSHPMAVMCGITGALAAFYHDSLDVNNPRHREI
                     AAFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAGNFLNMMFSTPCEPYEVNPILER
                     AMDRILILHADHEQNASTSTVRTAGSSGANPFACIAAGIASLWGPAHGGANEAALKML
                     EEISSVKHIPEFVRRAKDKNDSFRLMGFGHRVYKNYDPRATVMRETCHEVLKELGTKD
                     DLLEVAMELENIALNDPYFIEKKLYPNVDFYSGIILKAMGIPSSMFTVIFAMARTVGW
                     IAHWSEMHSDGMKIARPRQLYTGYEKRDFKSDIKR"
     gene            complement(1502..1609)
                     /locus_tag="RHX21_003365"
     CDS             complement(1502..1609)
                     /locus_tag="RHX21_003365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988511.1"
                     /translation="MRKSYEVGISPKINLCNSVEVLTNSFGTVISGRQV"
     gene            1990..2394
                     /gene="sdhC"
                     /locus_tag="RHX21_003366"
                     /gene_synonym="cybA"
                     /gene_synonym="dhsC"
     CDS             1990..2394
                     /gene="sdhC"
                     /locus_tag="RHX21_003366"
                     /gene_synonym="cybA"
                     /gene_synonym="dhsC"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase cytochrome b556 subunit"
                     /protein_id="HDV1988512.1"
                     /translation="MWALFMIRNVKKQRPVNLDLQTIRFPITAIASILHRVSGVITFV
                     AVGILLWLLGTSLSSPEGFEQASAIMGSFFVKFIMWGILTALAYHVVVGIRHMMMDFG
                     YLEETFEAGKRSAKISFVITVVLSLLAGVLVW"
     gene            2388..2735
                     /gene="sdhD"
                     /locus_tag="RHX21_003367"
                     /gene_synonym="cybS"
                     /gene_synonym="dhsD"
     CDS             2388..2735
                     /gene="sdhD"
                     /locus_tag="RHX21_003367"
                     /gene_synonym="cybS"
                     /gene_synonym="dhsD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase membrane anchor subunit"
                     /protein_id="HDV1988513.1"
                     /translation="MVSNASALGRNGVHDFILVRATAIVLTLYIIYMVGFFATSGELT
                     YEVWIGFFASAFTKVFTLLALFSILIHAWIGMWQVLTDYVKPLALRLMLQLVIVVALV
                     VYVIYGFVVVWGV"
     gene            2735..4501
                     /gene="sdhA"
                     /locus_tag="RHX21_003368"
     CDS             2735..4501
                     /gene="sdhA"
                     /locus_tag="RHX21_003368"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase flavoprotein subunit"
                     /protein_id="HDV1988514.1"
                     /translation="MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRS
                     HTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHM
                     GLPFSRLDDGRIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTI
                     FSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHIN
                     TGDGVGMAIRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERY
                     APNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELS
                     RTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEKGEDVVVPGLFAVGEIACV
                     SVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALRDASESDVEASLDRLNRWNNN
                     RNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNT
                     QRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPDRDDENWLCHSLYLPESESM
                     TRRSVNMEPKLRPAFPPKIRTY"
     gene            4517..5233
                     /gene="sdhB"
                     /locus_tag="RHX21_003369"
     CDS             4517..5233
                     /gene="sdhB"
                     /locus_tag="RHX21_003369"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase iron-sulfur subunit
                     SdhB"
                     /protein_id="HDV1988515.1"
                     /translation="MRLEFSIYRYNPDVDDAPRMQDYTLEAEEGRDMMLLDALIQLKE
                     KDPSLSFRRSCREGVCGSDGLNMNGKNGLACITPISALNQPGKKIVIRPLPGLPVIRD
                     LVVDMGQFYAQYEKIKPYLLNNGQNPPAREHLQMPEQREKLDGLYECILCACCSTSCP
                     SFWWNPDKFIGPAGLLAAYRFLIDSRDTETDSRLDGLSDAFSVFRCHSIMNCVSVCPK
                     GLNPTRAIGHIKSMLLQRNA"
     gene            5434..8235
                     /gene="sucA"
                     /locus_tag="RHX21_003370"
     CDS             5434..8235
                     /gene="sucA"
                     /locus_tag="RHX21_003370"
                     /EC_number="1.2.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="HDV1988516.1"
                     /translation="MQNSALKAWLDSSYLSGANQSWIEQLYEDFLTDPDSVDANWRST
                     FQQLPGTGVKPDQFHSQTREYFRRLAKDASRYSSTISDPDTNVKQVKVLQLINAYRFR
                     GHQHANLDPLGLWQQDKVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEAL
                     KQTYCGPIGAEYMHITSTEEKRWIQQRIESGRATFNSEEKKRFLSELTAAEGLERYLG
                     AKFPGAKRFSLEGGDALIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQ
                     DLFDEFAGKHKEHLGTGDVKYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSV
                     RARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQV
                     GFTTSNPLDARSTPYCTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFI
                     DLVCYRRHGHNEADEPSATQPLMYQKIKKHPTPRKIYADKLEQEKVATLEDATEMVNL
                     YRDALDAGDCVVAEWRPMNMHSFTWSPYLNHEWDEEYPNKVEMKRLQELAKRISTVPE
                     AVEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFF
                     HRHAVIHNQSNGSTYTPLQHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIW
                     EAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQL
                     CAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGT
                     FLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDVAIVRIEQLYPFPHKAM
                     QEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPFGASLRYAGRPASASPAVGY
                     MSVHQKQQQDLVNDALNVE"
     gene            8250..9467
                     /gene="odhB"
                     /locus_tag="RHX21_003371"
     CDS             8250..9467
                     /gene="odhB"
                     /locus_tag="RHX21_003371"
                     /EC_number="2.3.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="HDV1988517.1"
                     /translation="MSSVDILVPDLPESVADATVATWHKKPGDAVVRDEVLVEIETDK
                     VVLEVPASADGILDAVLEDEGTTVTSRQILGRLREGNSAGKETSAKSEEKASTPAQRQ
                     QASLEEQNNDALSPAIRRLLAEHNLDASAIKGTGVGGRLTREDVEKHLAKAPAKESAP
                     AAADPAAQPALAARSEKRVPMTRLRKRVAERLLEAKNSTAMLTTFNEVNMKPIMDLRK
                     QYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTP
                     RGLVTPVLRDVDTLGMADIEKKIKELAVKGRDGKLTVEDLTGGNFTITNGGVFGSLMS
                     TPIINPPQSAILGMHAIKDRPMAVNGQVEILPMMYLALSYDHRLIDGRESVGFLVTIK
                     ELLEDPTRLLLDV"
     gene            9561..10727
                     /gene="sucC"
                     /locus_tag="RHX21_003372"
     CDS             9561..10727
                     /gene="sucC"
                     /locus_tag="RHX21_003372"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-forming succinate--CoA ligase subunit beta"
                     /protein_id="HDV1988518.1"
                     /translation="MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWV
                     VKCQVHAGGRGKAGGVKVVNSKEDIRAFAENWLGKRLVTYQTDANGQPVNQILVEAAT
                     DIAKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQG
                     RELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGA
                     DGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIV
                     KLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVLVNIFGGIVRCDLIADGIIG
                     AVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKGLTDAAQQVVAAVEGK"
     gene            10727..11596
                     /gene="sucD"
                     /locus_tag="RHX21_003373"
     CDS             10727..11596
                     /gene="sucD"
                     /locus_tag="RHX21_003373"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate--CoA ligase subunit alpha"
                     /protein_id="HDV1988519.1"
                     /translation="MSILIDKNTKVICQGFTGSQGTFHSEQAIAYGTKMVGGVTPGKG
                     GTTHLGLPVFNTVREAVAATGATASVIYVPAPFCKDSILEAIDAGIKLIITITEGIPT
                     LDMLTVKVKLDEAGVRMIGPNCPGVITPGECKIGIQPGHIHKPGKVGIVSRSGTLTYE
                     AVKQTTDYGFGQSTCVGIGGDPIPGSNFIDILEMFEKDPQTEAIVMIGEIGGSAEEEA
                     AAYIKEHVTKPVVGYIAGVTAPKGKRMGHAGAIIAGGKGTADEKFAALEAAGVKTVRS
                     LADIGEALKTVLK"
     gene            complement(11700..12422)
                     /gene="mngR"
                     /locus_tag="RHX21_003374"
     CDS             complement(11700..12422)
                     /gene="mngR"
                     /locus_tag="RHX21_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-D-glycerate transport/metabolism system
                     transcriptional repressor MngR"
                     /protein_id="HDV1988520.1"
                     /translation="MGHKPLYRQIADRIREQIARGELKPGDALPTESALQTEFGVSRV
                     TVRQALRQLVEQQILESIQGSGTYVKEERVNYDIFQLTSFDEKLSDRHVDTHSEVLIF
                     EVIPADDFLQQQLQITAQDRVWHVKRVRYRKQKPMALEETWMPLALFPDLTWQVMENS
                     KYHFIEEVKKMVIDRSEQEIIPLMPTEEMSRLLNISQAKPILEKVSRGYLVDGRVFEY
                     SRNAFNTDDYKFTLIAQRKSSR"
     gene            12591..14507
                     /gene="mngA"
                     /locus_tag="RHX21_003375"
     CDS             12591..14507
                     /gene="mngA"
                     /locus_tag="RHX21_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001393949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS 2-O-a-mannosyl-D-glycerate transporter
                     subunit IIABC"
                     /protein_id="HDV1988521.1"
                     /translation="MNLTTLTHRDALCLNARFTSREEAIHALTQRLVALGKISSTEQF
                     LEEVYRRESLGPTALGEGLAVPHGKTAAVKEAAFAVATLSEPLQWEGVDGPEAVDLVV
                     LLAIPPNEAGTTHMQLLTALTTRLADDEIRARIQSATTPDELLSALDDKGGTQPSASF
                     SNAPTIVCVTACPAGIAHTYMAAEYLEKAGRKLGVNVYVEKQGANGIEGRLTADQLNS
                     ATACIFAAEVAIKESERFNGIPALSVPVAEPIRHAEALIQQALTLKRSDETRTVQQDT
                     QPVKSVKTELKQALLSGISFAVPLIVAGGTVLAVAVLLSQIFGLQDLFNEENSWLWMY
                     RKLGGGLLGILMVPVLAAYTAYSLADKPALAPGFAAGLAANMIGSGFLGAVVGGLIAG
                     YLMRWVKNHLRLSSKFNGFLTFYLYPVLGTLGAGSLMLFVVGEPVAWINNSLTAWLNG
                     LSGSNALLLGAILGFMCSFDLGGPVNKAAYAFCLGAMANGVYGPYAIFASVKMVSAFT
                     VTASTMLAPRLFKEFEIETGKSTWLLGLAGITEGAIPMAIEDPLRVIGSFVLGSMVTG
                     AIVGAMNIGLSTPGAGIFSLFLLHDNGAGGVMAAIGWFGAALVGAAISTAILLIWRRH
                     AVKHGNYLTDGVMP"
     gene            14525..17158
                     /gene="mngB"
                     /locus_tag="RHX21_003376"
     CDS             14525..17158
                     /gene="mngB"
                     /locus_tag="RHX21_003376"
                     /EC_number="3.2.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosylglycerate hydrolase"
                     /protein_id="HDV1988522.1"
                     /translation="MKAVSRVHITPHMHWDREWYFTTEESRILLVNNMEEILCRLEQD
                     NEYKYYVLDGQTAILEDYFAVKPENKDRVKKQVEAGKLIIGPWYTQTDTTIVSAESIV
                     RNLMYGMRDCLAFGEPMKIGYLPDSFGMSGQLPHIYNGFGITRTMFWRGCSERHGTDK
                     TEFLWQSSDGSEVTAQVLPLGYAIGKYLPADENGLRKRLDSYFDVLEKASVTKEILLP
                     NGHDQMPLQQNIFEVMEKLREIYPQRKFVMSRFEEVFEQIEAQRESLATLKGEFIDGK
                     YMRVHRTIGSTRMDIKIAHARIENKIVNLLEPLATLAWTLGFEYHHGLLEKMWKEILK
                     NHAHDSIGCCCSDKVHREIVARFELAEDMADNLIRFYMRKIADNMPQSDADKLVLFNL
                     MPWPREEVINTTVRLRASQFNLRDDRGQPVPYFIRHAREIDPGLIDRQIVHYGNYDPF
                     MEFDIQINQIVPSMGYRTLYIEANQPGNVIAAKSDAEGILENAFWQIALNEDGSLQLV
                     DKDSGVRYDRVLQIEESSDDGDEYDYSPAKEEWVITAANAKPQCDIIHEAWQSRAVIR
                     YEMAVPRNLQERSARQSTGRVGVEMVVTLSDNSRRIDVDINLDNQADDHRLRVLVPTP
                     FNTDSVLADTQFGSLTRPVNDSAMNNWQQEGWKEAPVPVWNMLNYAALQEGRNGMAVF
                     SEGLREFEVIGEEKKTFAITLLRGVGLLGKEDLLLRPGRPSGIKMPVPDSQLRGLLSC
                     RLSLLSYTGTPTAAGVAQQARAWLTPVQCYNKIPWDAMKLNKAGFNVPESYSLLKMPP
                     VGCLISALKKAEDRQEVILRLFNPAESATCDATVAFSREVISCSETMMDEHITTEENQ
                     GSNLSGPFLPGQSRTFSYRLA"
BASE COUNT         4198 a         4337 c         4735 g         4117 t
ORIGIN      
        1 agcaatcaac cattaacgct tgatatcgct tttaaagtcg cgtttttcat atcctgtata
       61 cagctgacgc ggacgggcaa tcttcatacc gtcactgtgc atttcgctcc agtgggcgat
      121 ccagccaacg gtacgtgcca ttgcgaaaat gacggtgaac atggaagacg gaatacccat
      181 cgctttcagg atgataccag agtagaaatc gacgttcggg tacagtttct tctcgataaa
      241 gtacgggtcg ttcagcgcga tgttttccag ctccatagcc acttccagca ggtcatcttt
      301 ggtgcccagc tctttcagaa cttcatggca ggtttcacgc attacggtgg cgcgcgggtc
      361 gtaatttttg tacacgcggt gaccgaagcc catcaggcgg aaagaatcat ttttatcttt
      421 cgcacgacga acaaattccg gaatgtgttt aacggagcta atttcttcca gcattttcag
      481 cgccgcttcg ttagcaccac cgtgcgcagg tccccacagt gaagcaatac ctgctgcgat
      541 acaggcaaac gggttcgcac ccgaagagcc agcggtacgc acggtggagg tagaggcgtt
      601 ctgttcatgg tcagcgtgca ggatcagaat acggtccata gcacgttcca gaatcggatt
      661 aacttcatac ggttcgcacg gcgtggagaa catcatattc aggaagttac cggcatagga
      721 gagatcgttg cgcggataaa caaatggctg accaatggaa tacttgtaac acatcgcggc
      781 catggtcggc attttcgaca gcaggcggaa cgcggcaatt tcacgatgac gaggattgtt
      841 aacatccagc gagtcgtgat agaacgccgc cagcgcgccg gtaataccac acatgactgc
      901 cattggatgt gagtcgcgac ggaaagcgtg gaacagacgg gtaatctgct cgtggatcat
      961 ggtatgacgg gtcaccgtag ttttaaattc gtcatactgt tcctgagtcg gtttttcacc
     1021 attcagcagg atgtaacaaa cttccaggta gttagaatcg gtcgccagct gatcgatcgg
     1081 gaaaccgcgg tgcagcaaaa taccttcatc accatcaata aaagtaattt tagattcgca
     1141 ggatgcggtt gaagtgaagc ctgggtcaaa ggtgaacaca ccttttgaac cgagagtacg
     1201 gatatcaata acatcttgac ccagcgtgcc tttcagcaca tccagttcaa cagctgtgtc
     1261 cccgttgagg gtgagttttg cttttgtatc agccatttaa ggtctcctta gcgccttatt
     1321 acgtaagact gccggaactt aaatttgcct tcgcacatca acctggcttt acccgtttgt
     1381 tatttggctc gccgctctgt gaaagagggg aaaacctggg tacagagctc tgggcgcttg
     1441 caggtaaagg atccattgat gacgaataaa tggcgaatca agtacttagc aatccgaatt
     1501 attaaacttg tctaccacta ataactgtcc cgaatgaatt ggtcaatact tccacactgt
     1561 tacataagtt aatcttaggt gaaataccga cttcataact tttacgcatt atatgctttt
     1621 cctggtaatg tttgtaacaa ctttgttgaa tgattgtcaa attagatgat taaaaattaa
     1681 ataaatgttg ttatcgtgac ctggatcact gttcaggata aaacccgaca aactatatgt
     1741 aggttaattg taatgatttt gtgaacagcc tatactgccg ccaggtctcc ggaacaccct
     1801 gcaatcccga gccacccagc gttgtaacgt gtcgttttcg catctggaag cagtgttttg
     1861 catgacgcgc agttatagaa aggacgctgt ctgacccgca agcagaccgg aggaaggaaa
     1921 tcccgacgtc tccaggtaac agaaagttaa cctctgtgcc cgtagtcccc agggaataat
     1981 aagaacagca tgtgggcgtt attcatgata agaaatgtga aaaaacaaag acctgttaat
     2041 ctggacctac agaccatccg gttccccatc acggcgatag cgtccattct ccatcgcgtt
     2101 tccggtgtga tcacctttgt tgcagtgggc atcctgctgt ggcttctggg taccagcctc
     2161 tcttcccctg aaggtttcga gcaagcttcc gcgattatgg gcagcttctt cgtcaaattt
     2221 atcatgtggg gcatccttac cgctctggcg tatcacgtcg tcgtaggtat tcgccacatg
     2281 atgatggatt ttggctatct ggaagaaaca ttcgaagcgg gtaaacgctc cgccaaaatc
     2341 tcctttgtta ttactgtcgt gctttcactt ctcgcaggag tcctcgtatg gtaagcaacg
     2401 cctccgcatt aggacgcaat ggcgtacatg atttcatcct cgttcgcgct accgctatcg
     2461 tcctgacgct ctacatcatt tatatggtcg gttttttcgc caccagtggc gaactgacat
     2521 atgaagtctg gatcggtttc ttcgcctctg cgttcaccaa agtgttcacc ctgctggcgc
     2581 tgttttctat cttgattcat gcctggatcg gcatgtggca ggtgttgacc gactacgtta
     2641 aaccgctggc attgcgcctg atgctgcaac tggtgattgt cgttgcactg gtggtttacg
     2701 tgatttatgg attcgttgtg gtgtggggtg tgtgatgaaa ttgccagtca gagaatttga
     2761 tgcagttgtg attggtgccg gtggcgcagg tatgcgcgcg gcgctgcaaa tttcccagag
     2821 cggccagacc tgtgcgctgc tctctaaagt cttcccgacc cgttcccata ccgtttctgc
     2881 gcaaggcggc attaccgttg cgctgggtaa tacccatgaa gataactggg aatggcatat
     2941 gtacgacacc gtaaaagggt cggactatat cggtgaccag gacgcgattg aatatatgtg
     3001 taaaaccggg ccggaagcga ttctggaact cgaacacatg ggcctgccgt tctcgcgtct
     3061 tgatgatggt cgtatctatc aacgtccgtt tggcggtcag tcgaaaaact tcggcggcga
     3121 gcaggcggca cgcactgcgg cggcggctga ccgtaccggt cacgcactgt tgcacacgct
     3181 ttatcagcag aacctgaaaa accacaccac cattttctcc gagtggtatg cgctggatct
     3241 ggtgaaaaac caggatggcg cggtggtggg ttgtaccgca ctgtgcatcg aaaccggtga
     3301 agtggtttat ttcaaagccc gcgctaccgt gctggcgact ggcggggcag ggcgtattta
     3361 tcagtccacc actaacgccc acattaacac tggcgacggc gtcggcatgg ctatccgcgc
     3421 aggcgtaccg gtgcaggata tggaaatgtg gcagttccac ccgaccggta ttgccggtgc
     3481 gggcgtactg gtcaccgaag gttgccgtgg tgaaggcggt tatctgctga acaaacatgg
     3541 cgaacgcttt atggagcgtt atgcgccgaa cgccaaagac ctggcgggcc gtgacgtggt
     3601 ggcgcgttcc atcatgattg aaatccgtga aggtcgcggc tgtgatggtc cgtgggggcc
     3661 acatgcgaaa ctgaaactcg accacctggg taaagaagtt ctcgaatccc gtctgccggg
     3721 tattctggaa ctctcccgta ccttcgctca cgttgatccg gtgaaagagc cgattccggt
     3781 tatcccaacc tgtcactaca tgatgggtgg tattccgacc aaagtgaccg gtcaggcgct
     3841 gacggtgaac gagaaaggcg aagatgtggt tgttccgggg ctgtttgccg ttggtgaaat
     3901 cgcttgtgta tcggtacacg gcgctaaccg tctgggcggc aactcgctgc tggacctggt
     3961 ggtctttggt cgcgcagcgg gtctgcatct gcaagagtct atcgccgagc agggcgcatt
     4021 gcgcgatgcc agcgagtctg atgttgaagc atctctggat cgtctgaacc gctggaacaa
     4081 taatcgtaac ggtgaagatc cggtggcgat tcgtaaagcg ctgcaagaat gtatgcagca
     4141 taacttctcg gtcttccgtg aaggtgatgc gatggcgaaa gggcttgagc agttgaaagt
     4201 tatccgcgag cgtctgaaaa atgcccgtct ggatgacact tccagcgagt tcaacaccca
     4261 gcgcgttgag tgcctggaac tggataacct gatggaaacg gcgtatgcaa cggctgtttc
     4321 tgccaacttc cgtaccgaaa gccgtggcgc gcatagccgc ttcgacttcc cggatcgtga
     4381 tgatgaaaac tggctgtgcc actccctgta tctgccagag tcggaatcca tgacgcgccg
     4441 aagcgtcaac atggaaccga aactgcgccc ggcattcccg ccgaagattc gtacttacta
     4501 atgcggagac aggaaaatga gactcgagtt ttcaatttat cgctataacc cggatgttga
     4561 tgatgctccg cgtatgcagg attacaccct ggaagcggaa gaaggtcgcg acatgatgtt
     4621 gctggatgcg cttatccagc tgaaagagaa agatcccagc ctgtcgttcc gccgctcctg
     4681 ccgtgaaggt gtgtgcggtt ccgacggtct gaacatgaac ggcaagaatg gtctggcctg
     4741 tattaccccg atttcggcac tcaaccagcc gggcaagaag attgtgattc gcccgctgcc
     4801 aggtttaccg gtgatccgcg atttggtggt agacatggga caattctatg cgcaatatga
     4861 gaaaattaag ccttacctgt tgaataatgg acaaaatccg ccagctcgcg agcatttaca
     4921 gatgccagag cagcgcgaaa aactcgacgg gctgtatgaa tgtattctct gcgcatgttg
     4981 ttcaacctct tgtccgtctt tctggtggaa tcccgataag tttatcggcc cggcaggctt
     5041 gttagcggca tatcgtttcc tgatcgatag ccgtgatacc gagactgaca gccgcctcga
     5101 cggtttgagc gatgcattca gtgtattccg ctgtcacagc atcatgaact gcgtcagtgt
     5161 atgtccgaag gggctgaacc cgacgcgcgc catcggccat atcaagtcga tgttgttgca
     5221 acgtaatgcg taattaaatg ttgatgccgg ggaaatcccc cggctattca ggaaatcttt
     5281 aaaaactgcc cctgacacta agacagtttt taaaggttcc ttcgcgagcc actacgtaga
     5341 caagagctcg caagtgaacc ccggcacgca cataactgtg cgtggtagta tccacggcga
     5401 agtaagcata aaaaagatgc ttaagggatc acgatgcaga acagcgcttt gaaagcctgg
     5461 ttggactctt cttacctctc tggcgcaaac cagagctgga tagaacagct ctatgaagac
     5521 ttcttaaccg atcctgactc ggttgacgct aactggcgtt cgacgttcca gcagttacct
     5581 ggtacgggag tcaaaccgga tcaattccac tctcaaacgc gtgaatattt ccgccgcctg
     5641 gcgaaagacg cttcacgtta ctcttcaacg atctccgacc ctgacaccaa tgtaaagcag
     5701 gttaaagtcc tgcagctcat taacgcatac cgcttccgtg gtcaccagca tgcgaatctc
     5761 gatccgctgg gactgtggca gcaagataaa gtggccgatc tggatccgtc tttccacgat
     5821 ctgaccgaag cagacttcca ggagaccttc aacgtcggtt catttgccag cggcaaagaa
     5881 accatgaaac tcggcgagct gctggaagcc ctcaagcaaa cctactgcgg cccgattggt
     5941 gccgagtata tgcacattac cagcaccgaa gaaaaacgct ggatccaaca gcgtatcgag
     6001 tctggtcgcg cgactttcaa tagcgaagag aaaaaacgct tcttaagcga actgaccgcc
     6061 gctgaaggcc ttgaacgtta cctcggcgca aaattccctg gcgcaaaacg cttctcgctg
     6121 gaaggcggtg acgcgttaat cccgatgctt aaagagatga tccgccacgc tggcaacagc
     6181 ggcacccggg aagtggttct cgggatggcg caccgtggtc gtctgaacgt gttggtgaac
     6241 gtgctgggta aaaaaccgca agacttgttc gacgagtttg ccggtaaaca taaagaacac
     6301 ctcggcacgg gtgacgtgaa ataccacatg ggcttctcgt ctgacttcca gaccgatggc
     6361 ggcctggtgc acctggcgct ggcgtttaac ccgtctcacc ttgagattgt aagcccggtc
     6421 gttatcggct ctgttcgtgc ccgtctggac agacttgatg agccgagcag caacaaagtg
     6481 ctgccaatta ccatccacgg tgacgccgca gtgaccggac agggcgtggt tcaggaaacc
     6541 ctgaacatgt cgaaagcgcg tggttatgaa gttggcggta cggtacgtat cgttatcaac
     6601 aaccaggttg gtttcaccac ctctaatccg ctggatgccc gttctacgcc gtactgtact
     6661 gatatcggca agatggttca ggcaccgatt ttccacgtta acgcggacga tccggaagcc
     6721 gttgcctttg tgacccgtct ggcgctcgat ttccgtaaca cctttaaacg tgatgtcttc
     6781 atcgacctgg tatgctaccg ccgtcacggc cacaacgaag ccgacgagcc gagcgcaacc
     6841 cagccgctga tgtatcagaa aatcaaaaaa catccgacac cgcgcaaaat ctacgctgac
     6901 aagctggagc aggaaaaagt ggcgacgctg gaagatgcca ccgagatggt taacctgtac
     6961 cgcgatgcgc tggatgctgg cgattgcgtg gtagcagagt ggcgtccgat gaacatgcac
     7021 tctttcacct ggtcgccgta cctcaaccac gaatgggacg aagagtaccc gaacaaagtt
     7081 gagatgaagc gcctgcagga actggctaaa cgcatcagca cggtgccgga agcggttgaa
     7141 atgcagtctc gcgttgccaa gatttatggc gatcgccagg cgatggctgc cggtgagaaa
     7201 ctgttcgact ggggcggcgc ggaaaacctc gcttacgcca cgctggttga cgaaggcatt
     7261 ccggttcgcc tgtcgggtga agactccggt cgcggtacct tcttccaccg ccacgcggtg
     7321 atccacaacc agtctaacgg ttccacttac acgccgctgc aacacatcca taacggccag
     7381 ggcgcgttcc gtgtttggga ctccgtactg tctgaagaag cagtgctggc gtttgaatac
     7441 ggttatgcca ccgcagaacc acgcaccctg accatctggg aagcgcagtt cggtgacttc
     7501 gccaacggtg cgcaggtggt tatcgaccag ttcatctcct ctggcgagca gaaatggggc
     7561 cggatgtgtg gtctggtgat gttgctgccg cacggttacg aagggcaggg gccggagcac
     7621 tcctccgcgc gtctggaacg ttatctgcaa ctttgtgctg agcaaaacat gcaggtttgc
     7681 gtaccgtcta ccccggcaca ggtttaccac atgctgcgtc gtcaggcgct gcgcgggatg
     7741 cgtcgtccgc tggtcgtgat gtcgccgaaa tccctgctgc gtcatccgct ggcggtttcc
     7801 agcctcgaag aactggcgaa cggcaccttc ctgccagcca tcggtgaaat cgacgagctt
     7861 gatccgaagg gcgtgaagcg cgtagtaatg tgttctggta aggtttatta cgacctgctg
     7921 gaacagcgtc gtaagaacaa tcaacacgat gtcgccattg tgcgtatcga gcaactctac
     7981 ccgttcccgc ataaagcgat gcaggaagtg ttgcagcagt ttgctcacgt caaggatttt
     8041 gtctggtgcc aggaagagcc gctcaaccag ggcgcatggt actgcagcca gcatcatttc
     8101 cgtgaagtga ttccgtttgg ggcttctctg cgttatgcag gccgcccggc ctccgcctct
     8161 ccggcggtag ggtatatgtc cgttcaccag aaacagcaac aagatctggt taatgacgcg
     8221 ctgaacgtcg aataaataaa ggatacacaa tgagtagcgt agatattctg gtccctgacc
     8281 tgcctgaatc cgtagccgat gccaccgtcg caacctggca taaaaaaccc ggcgacgcag
     8341 tcgtacgtga tgaagtgctg gtagaaatcg aaactgacaa agtggtactg gaagtaccgg
     8401 catcagcaga cggcattctg gatgcggttc tggaagatga aggtacaacg gtaacgtctc
     8461 gtcagatcct tggtcgcctg cgtgaaggca acagcgccgg taaagaaacc agcgccaaat
     8521 ctgaagagaa agcgtccact ccggcgcaac gccagcaggc gtctctggaa gagcaaaaca
     8581 acgatgcgtt aagcccggcg atccgtcgcc tgctggctga acacaatctc gacgccagcg
     8641 ccattaaagg caccggtgtg ggtggtcgtc tgactcgtga agatgtggaa aaacatctgg
     8701 cgaaagcccc ggcgaaagag tctgctccgg cagcggctga tccggcggcg caaccggctc
     8761 tggctgcacg tagtgaaaaa cgtgtcccga tgactcgcct gcgtaagcgt gtggcagagc
     8821 gtctgctgga agcgaaaaac tccaccgcca tgctgaccac gttcaacgaa gtcaacatga
     8881 agccgattat ggatctgcgt aagcagtacg gtgaagcgtt tgaaaaacgc cacggcatcc
     8941 gtctgggctt tatgtccttc tacgtgaaag cggtggttga agccctgaaa cgttacccgg
     9001 aagtgaacgc gtctatcgac ggcgatgacg tggtttacca caactatttc gacgtcagca
     9061 tggcggtttc tacgccgcgc ggcctggtga caccggtact gcgtgatgtc gataccctcg
     9121 gcatggcaga catcgagaag aaaatcaaag agctggcagt caaaggccgt gacggcaagc
     9181 tgaccgttga agatctgacc ggtggtaact tcaccatcac caacggtggt gtgttcggtt
     9241 ccctgatgtc tacgccgatc atcaacccgc cgcagagcgc aattctgggt atgcacgcta
     9301 tcaaagatcg tccgatggcg gtgaatggtc aggttgagat cctgccgatg atgtacctgg
     9361 cgctgtccta cgatcaccgt ctgatcgatg gtcgcgaatc cgtgggcttc ctggtaacga
     9421 tcaaagagtt gctggaagat ccgacgcgtc tgctgctgga cgtgtagtag tttaagcttc
     9481 acctgcactg tagaccgacg tggatagggt gtcggtctac ggtttaaaag ataacgatta
     9541 ctgaaggatg gacagaacac atgaacttac atgaatatca ggcaaaacaa ctttttgccc
     9601 gctatggctt accagcaccg gtgggttatg cctgtactac tccgcgcgaa gcagaagaag
     9661 ccgcttcaaa aatcggtgcc ggcccgtggg tagtgaaatg tcaggttcac gctggtggcc
     9721 gcggtaaagc gggcggtgtg aaagttgtaa acagcaaaga agacatccgt gcttttgcag
     9781 aaaactggct cggcaagcgt ctggtaacgt atcaaacaga tgccaatggc caaccggtta
     9841 accagattct ggttgaagca gcgaccgata tcgctaaaga gctgtatctc ggtgccgttg
     9901 tagaccgtag ttcccgtcgc gtggtcttta tggcctccac cgaaggcggc gtggaaatcg
     9961 aaaaagtggc ggaagaaact ccgcacctga tccataaagt tgcgcttgat ccgctgacag
    10021 gcccgatgcc gtatcaggga cgcgagctgg cgttcaaact gggtctggaa ggtaaactgg
    10081 ttcagcagtt caccaaaatc ttcatgggcc tggcgaccat tttcctggag cgcgacctgg
    10141 cgttgatcga aatcaacccg ctggtcatca ccaaacaggg cgatctgatt tgcctcgacg
    10201 gcaaactggg cgctgacggc aacgcactgt tccgccagcc tgatctgcgc gaaatgcgtg
    10261 accagtcgca ggaagatccg cgtgaagcac aggctgcaca gtgggaactg aactacgttg
    10321 cgctggacgg taacatcggt tgtatggtta acggcgcagg tctggcgatg ggtacgatgg
    10381 acatcgttaa actgcacggc ggcgaaccgg ctaacttcct tgacgttggc ggcggcgcaa
    10441 ccaaagaacg tgtaaccgaa gcgttcaaaa tcatcctctc tgacgacaaa gtgaaagccg
    10501 ttctggttaa catcttcggc ggtatcgttc gttgcgacct gatcgctgac ggtatcatcg
    10561 gcgcggtagc agaagtgggt gttaacgtac cggtcgtggt acgtctggaa ggtaacaacg
    10621 ccgaactcgg cgcgaagaaa ctggctgaca gcggcctgaa tattattgca gcaaaaggtc
    10681 tgacggatgc agctcagcag gttgttgccg cagtggaggg gaaataatgt ccattttaat
    10741 tgataaaaac accaaggtta tctgccaggg ctttactggt agccagggga ctttccactc
    10801 agaacaggcc attgcatacg gcactaaaat ggttggcggc gtaaccccag gtaaaggcgg
    10861 tactacccac ctcggcctgc cggtgttcaa caccgtgcgt gaagctgttg ctgctactgg
    10921 cgctaccgct tctgttatct acgtaccagc accgttctgc aaagactcca ttctggaagc
    10981 tattgatgca ggcatcaaac tgattatcac catcactgaa ggcatcccga cgctggatat
    11041 gctgactgtg aaagtgaaac tggacgaagc cggcgttcgt atgatcggcc cgaactgccc
    11101 gggcgttatc actccgggtg aatgcaaaat cggtatccag ccgggtcaca ttcacaaacc
    11161 gggtaaagtg ggtatcgttt cccgttccgg tacactgacc tatgaagcgg ttaaacagac
    11221 cacggattac ggtttcggtc agtcgacctg tgttggtatc ggcggtgacc cgatccctgg
    11281 ctctaacttt atcgacattc tcgaaatgtt cgaaaaagat ccgcagaccg aagcgatcgt
    11341 aatgatcggt gagatcggcg gtagcgctga agaagaagcg gcagcgtaca tcaaagagca
    11401 tgttaccaag ccagttgtgg gttacatcgc tggtgtgact gcgccgaaag gcaaacgtat
    11461 gggccacgcg ggtgccatca ttgccggtgg gaaagggact gcggatgaga aatttgctgc
    11521 tctggaagcc gcaggcgtga aaaccgttcg cagcctggcg gatatcggtg aagcactgaa
    11581 aactgttctg aaataaatat ctgtaataag aaatagccct cgccgcttcc ctctacagga
    11641 atggcgaagg gctgtcggtt tcgacatggt tggccatcgt atgatggcct tttttgtgct
    11701 tatcgcgatg attttcgttg cgctatcagg gtaaatttat agtcatcggt attaaaagcg
    11761 ttgcggctat attcaaacac ccgaccatca actaaatatc cacgcgatac tttttcaaga
    11821 atcggctttg cctggctgat attaagcaga cggctcatct cttcggttgg catcagagga
    11881 atgatttcct gttcgctacg atcgataacc attttcttca cttcttcaat aaagtgatat
    11941 tttgaatttt ccatgacctg ccaggtgaga tccgggaaca acgcaagcgg catccaggtt
    12001 tcttccagcg ccattggctt ttgcttgcga tagcgcacgc gcttcacatg ccacacacga
    12061 tcctgcgcgg tgatttgtag ctgttgctga agaaaatcgt cagccggaat cacttcaaat
    12121 atcaggactt cactgtgtgt atcgacgtga cggtccgaca gtttttcatc aaaactggtt
    12181 aactgaaaaa tatcgtaatt gacccgctct tctttgacgt aagtcccgct gccctgaatg
    12241 ctttcgagga tctgttgctc gactaactgg cgcaaagcct gacgcaccgt aacccggctg
    12301 acgccaaact ctgtttgtaa tgccgattcg gtaggtaacg catcgccagg tttaagctcg
    12361 ccacgcgcaa tttgttcacg aatgcgatcg gcaatctgcc ggtataaggg cttgtgtccc
    12421 atttttagta tctcattaat acgaatttag ccattatgcc cgataaattc atcctgtaaa
    12481 taatacaaat acaatacaaa taatttcaat caagtgaaat tgatcacata atggtattgt
    12541 tttatcgggc acactggcgc gactataaaa acgatcaagt gaggatcatg atgaatctga
    12601 cgactctgac ccaccgcgat gcgttgtgtc tgaatgcgcg ctttaccagc cgtgaagagg
    12661 ccatccacgc gttgactcaa cgtcttgttg ctctggggaa aatttccagt actgagcaat
    12721 ttctggaaga agtgtatcgc cgtgaaagcc ttggcccgac cgccttaggt gaagggttgg
    12781 ctgtgccgca tggcaaaact gctgcggtaa aagaagcggc gtttgcggtc gccacactca
    12841 gcgagccgct tcagtgggaa ggcgttgatg gcccggaagc ggttgattta gtggtgctgc
    12901 tggcgattcc ccccaatgaa gcgggtacta cgcatatgca actgctgaca gcgctgacca
    12961 cgcgcctggc ggatgatgag attcgggcgc gtatacagtc ggcgacgacg cctgatgagt
    13021 tgctctcggc gctggatgac aagggaggca cgcaaccttc tgcctctttt tccaacgcgc
    13081 caactatcgt ctgcgtaacg gcctgtccgg cgggtattgc tcacacctat atggctgcgg
    13141 aatatctgga aaaagccgga cgcaaactcg gcgtaaatgt ttacgttgaa aaacaaggcg
    13201 ctaacggcat tgaagggcgt ttaacggcgg atcaactcaa tagtgcaacc gcctgtattt
    13261 ttgcggctga agtcgccatc aaggagagtg agcgttttaa tggcattccc gcgctttcag
    13321 tgcctgttgc cgagccgatt cgccatgcag aagcgttgat ccaacaagcg cttaccctca
    13381 agcgtagcga tgagacgcgt accgtacagc aagatacgca accggtgaaa agtgtcaaaa
    13441 cggagctgaa acaggcactg ttgagcggaa tctcttttgc cgtaccgttg attgtcgcgg
    13501 ggggcacggt gctggcggtc gcggtattac tgtcgcaaat cttcgggcta caagatctgt
    13561 ttaatgaaga aaactcctgg ctgtggatgt accgcaagct gggcggcggg ctgctcggaa
    13621 ttttgatggt accggtgctc gcggcctata ccgcctattc tctggcagat aaaccggcgt
    13681 tagcgccagg ctttgcggct ggacttgccg ccaacatgat cggctccggg tttctcggcg
    13741 cggtcgttgg cggattgata gccggttact tgatgcgctg ggtgaaaaat cacttgcgtc
    13801 ttagcagtaa attcaatgga ttcctgactt tttatctcta cccggtgctc ggtacgttgg
    13861 gagcgggcag tctgatgctg tttgtggtgg gagaacctgt cgcctggatc aataactcgc
    13921 ttaccgcctg gctgaacggt ctgtcaggaa gtaacgcgct gttgctgggt gccattctcg
    13981 gttttatgtg ttcctttgac cttggagggc cagtgaacaa agccgcttat gcattctgcc
    14041 tgggcgcaat ggcgaacggc gtttacggcc cgtatgccat tttcgcctcc gtcaaaatgg
    14101 tttcggcatt taccgtaacc gcttccacga tgctcgcacc gcgcctgttt aaagagtttg
    14161 aaattgagac cgggaaatcc acctggctgt tagggctggc aggtattacc gaaggggcga
    14221 tcccgatggc gattgaagat ccgctgcggg ttattggttc gtttgtgctg ggctctatgg
    14281 taacgggcgc tattgtcggt gcgatgaata tcggcctttc gacacccggt gccggcattt
    14341 tctcgctctt tttacttcat gataatggcg cgggcggtgt tatggcggca attggctggt
    14401 ttggtgcggc attggtgggg gctgcaatct cgactgcaat tctcctgatc tggcggcgtc
    14461 acgcggttaa gcatggcaac tatctgactg atggcgtaat gccataaaca aaaaggaaac
    14521 gacgatgaaa gcggtatctc gcgttcacat caccccgcat atgcattggg atcgggagtg
    14581 gtatttcacc accgaagagt cacgcattct gctggtcaat aatatggaag agatcctgtg
    14641 ccgactggaa caggacaacg aatacaaata ttacgtactc gacgggcaaa cggcgatcct
    14701 cgaagattat ttcgcggtga aaccggaaaa caaagaccgc gtgaagaaac aggtagaagc
    14761 cggtaagttg attatcggcc cctggtatac ccagaccgat accacgattg tttctgcgga
    14821 atccatcgtc cgtaatctga tgtacggaat gcgtgactgc ctcgcgtttg gcgagccgat
    14881 gaaaataggt tatttaccgg attcctttgg catgtccggg caactgccgc atatctacaa
    14941 tggatttggc attacccgca ctatgttctg gcgcggatgt tcggagcgcc acggtactga
    15001 taaaaccgag tttttatggc aaagcagtga cggtagcgaa gtgacggcgc aggtgctgcc
    15061 gttgggttat gccatcggta agtacttacc tgccgacgaa aacggattac gcaaacgcct
    15121 cgacagttat tttgacgtgc tggaaaaagc gtctgtaacc aaagagattt tattgccgaa
    15181 tggtcatgac cagatgccat tgcagcaaaa tatcttcgaa gtgatggaga aacttcgcga
    15241 aatttatcct caacgaaagt ttgtgatgag ccgctttgaa gaggtattcg agcagattga
    15301 agcgcagcgt gaaagtctgg caaccctgaa aggggaattt attgatggca aatatatgcg
    15361 cgtgcatcgc accatcggtt ctacgcgtat ggatatcaaa attgcccacg cgcgtattga
    15421 aaataagatt gttaatctgc tggaaccgct ggcaacactg gcctggacgt tgggttttga
    15481 ataccaccac ggcttgctgg agaaaatgtg gaaagagatc ttaaaaaatc atgcccacga
    15541 cagtatcggt tgttgttgca gtgacaaagt tcatcgcgaa atcgtcgccc gcttcgaact
    15601 ggctgaagac atggcggata atctgattcg tttctacatg cgcaaaattg ccgacaacat
    15661 gccgcagagc gacgccgaca aactcgtcct gtttaacctg atgccctggc cgcgtgaaga
    15721 agtgatcaac accactgtgc gcctgcgcgc cagccagttt aatttgcggg acgatcgcgg
    15781 ccagcctgtg ccgtatttta ttcgccatgc ccgtgagatc gatccaggcc taatcgatcg
    15841 gcaaattgtt cattatggca attatgatcc ctttatggag ttcgacatcc agatcaacca
    15901 gattgtccct tctatgggct atcgcacgct ttatattgaa gcgaatcagc ctggcaacgt
    15961 gattgcggca aaaagtgacg ctgaagggat tctggaaaat gctttctggc agattgcgct
    16021 caatgaggat ggttctctgc aactggtaga taaagacagc ggtgtgcgct atgaccgggt
    16081 attgcaaatt gaagaaagct ctgatgatgg tgatgaatat gactattcac ccgcaaaaga
    16141 agagtgggta attaccgcgg cgaacgcgaa accgcaatgc gatattattc atgaagcctg
    16201 gcagagcagg gctgttatcc gttatgaaat ggcggtgccg cgtaatctgc aagaacgcag
    16261 cgcaagacaa tccactggca gagtaggggt ggaaatggtt gtcactttga gtgataacag
    16321 caggcgcatt gatgtggata tcaaccttga taaccaggct gacgatcatc gtcttcgcgt
    16381 cctggtccct acacctttta acaccgacag tgttctggca gatacccagt ttggttcgct
    16441 aacgcgcccc gtgaacgaca gtgcaatgaa caactggcag caagaaggct ggaaagaagc
    16501 gccggttccg gtatggaata tgctcaacta tgctgcctta caggaagggc gtaacggcat
    16561 ggctgtcttt agcgaagggt tacgtgaatt tgaagtcatc ggtgaagaga agaaaacctt
    16621 tgccattacg ttgctgcgtg gcgtgggctt actggggaaa gaagatctgc ttttaaggcc
    16681 tgggcggcct tcgggaatta aaatgccagt cccggactca caactacgtg gtctgctttc
    16741 ttgtcgccta agtttattga gttataccgg tacgccaacc gccgctggtg tagctcagca
    16801 ggcgcgagca tggctgactc cagtacagtg ttacaacaaa atcccatggg atgcgatgaa
    16861 gctcaacaaa gccggattca acgtgccgga aagttatagt ttgttgaaaa tgcccccagt
    16921 gggatgcctg ataagcgcac ttaagaaagc tgaagaccga caagaagtga ttttacggct
    16981 gtttaatccg gctgaatcag caacctgtga tgcgactgtt gctttcagtc gcgaggtgat
    17041 ttcttgctca gaaacgatga tggatgaaca cattaccacc gaggaaaatc aaggttcaaa
    17101 tctatcgggg ccttttttac ccggccagtc acggacgttc agttaccggc ttgcctgaat
    17161 agcaatcaaa ccgaagccac atatgcgcgg ccagattgtt gacaaagggc gctttgttca
    17221 tgccggatac ggcatgaacg ctttattcgg tctacaaaag caggcaaatt caatatattg
    17281 cagagatgat gtagacactg gcaagcgtag cgcatcaggt aattttgcgt ttatcttcac
    17341 tctcaagcca cgtatatgtg gctttatttt taacaaaata ataaccc
//
LOCUS       DAPGUL010000095        17291 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.097, whole genome shotgun sequence.
ACCESSION   DAPGUL010000095 DAPGUL010000000
VERSION     DAPGUL010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17291
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.097"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            91..675
                     /locus_tag="RHX21_003377"
     CDS             91..675
                     /locus_tag="RHX21_003377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDV1988523.1"
                     /translation="MNKVTKTAIVGLLALFAGNAAATDGEIVFDGEILKSACEINDSD
                     KKIEVALGHYNAEQFRSVGDRSPKIPFTIPLVNCPVTGWEHDNGNVEASFRLWLETRD
                     NGTVPNFPNLAKVGSFAGTAATGVGIRIDDAESGNLMPLNAMGNDNTVYQIPADSNGI
                     VNVDLIAYYVSTVEASEITPGEADAVVNVTLDYR"
     gene            755..1450
                     /locus_tag="RHX21_003378"
     CDS             755..1450
                     /locus_tag="RHX21_003378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HDV1988524.1"
                     /translation="MSKRTFAVIITLLCSFCIGQALAGGIVLQRTRVIYDASRKEAAL
                     PVANKGAETPYLLQSWVDNIDGTSRAPFIITPPLFRLEAGDDSSLRIIKTADNLPENK
                     ESLFYINVRAIPAKKKSDDVNANELTLVFKTRIKMFYRPAHLKGRVNDAWTSLEFKRS
                     DHSLNIYNPTEYYVVFAGLAVDKTDLTSKIEYIAPGEHKQLPLPASGGKNVKWAAIND
                     YGGSSGTETRPLQ"
     gene            1480..3996
                     /locus_tag="RHX21_003379"
     CDS             1480..3996
                     /locus_tag="RHX21_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDV1988525.1"
                     /translation="MPQRHHQGHKRTPKQLALIIKRCLPMVLTGSGMLCTTANAEEYY
                     FDPIMLETTKSGMQTTDLSRFSKKYAQLPGTYQVDIWLNKKKVSQKKITFTANAEQLL
                     QPQFTVEQLRELGIKVDEIPALAEKDDDSVINSLEQIIPGTAAEFDFNHQRLNLSIPQ
                     IALYRDAKGYVSPSRWDDGIPTLFTNYSFTGSDNRYRQGNRSQRQYLNMQNGANFGPW
                     RLRNYSTWTRNDQASSWNTISSYLQRDIKALKSQLLLGESATSGSIFSSYTFTGVQLA
                     SDDNMLPNSQRGFAPTVRGIANSSAIVTIRQNGYVIYQSNVPAGAFEINDLYPSSNSG
                     DLEVTIEESDGTQRRFIQPYSSLPMMQRPGHLKYSATAGRYRADANSDSKEPEFAEAT
                     AIYGLNNTFTLYGGLLGSEDYYALGIGIGGTLGALGALSMDINRADTQFDNRHSFHGY
                     QWRTQYIKDIPETNTNIAVSYYRYTNDGYFSFDEANTRNWDYNSRQKSEIQFNISQTI
                     FDGVSLYASGSQQDYWGNNDKNRNISVGVSGQQWGIGYSLNYQYSRYTDQNNDRALSL
                     NLSIPLERWLPRSRVSYQMTSQKDRPTQHEMRLDGSLLDDGRLSYSLEQSLDDDNNHN
                     SSLNASYRSPYGTFSAGYSYGNDSSQYNYGVTGGVVIHPHGVTLSQYLGNAFALIDAN
                     GASGVRIQNYPGIATDPFGYAVVPYLTTYQENRLSVDTTQLPDNVDLEQTTQFVVPNR
                     GAMVAARFNANIGYRVLVTVSDRNGKPLPFSALASNDETGQQSIVDEGGILYLSGISS
                     KSQSWTVRWGNQADQQCQFAFSTPDSEPTTSVLQGTAQCH"
     gene            4007..5098
                     /locus_tag="RHX21_003380"
     CDS             4007..5098
                     /locus_tag="RHX21_003380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV1988526.1"
                     /translation="MKRAPLITGLLLISTSCAYASSGGCGADSTSGATNYSSVVDDVT
                     VNQTDNVTGREFTSATLSSTNWQYACTCSAGKAVKLVYMVSPVLTTTGHQAGYYKLND
                     SLDIKTTLQANDIPGLVTDQTVSVNTRFTQIKSNTVYSAATQTGVCQGDTSRYGPVNI
                     GANTTFTLYVTKPFLGSMTIPKTDIAVIKGAWVDGMGSPSTGDFHDLVKLSIQGNLTA
                     PQSCKINQGDVIKVNFGFINGQKFTTRNAMPDGFTPVDFNITYDCGDTSKIKNSLQMR
                     IDGTTGVVDQYNLVARRRSSDNAPDVGIRIENLGGGVANIPFQNGILPVDPSGHGTIN
                     MRAWPVNLVGGELETGKFQGTATITVIVR"
     gene            complement(5141..6001)
                     /gene="rsmI"
                     /locus_tag="RHX21_003381"
     CDS             complement(5141..6001)
                     /gene="rsmI"
                     /locus_tag="RHX21_003381"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HDV1988527.1"
                     /translation="MKQHQSADNSQGQLYIVPTPIGNLADITQRALEVLQAVDLIAAE
                     DTRHTGLLLQHFGINARLFALHDHNEQQKAETLLAKLQEGQNIALVSDAGTPLINDPG
                     YHLVRTCREAGICVVPLPGPCAAITALSAAGLPSDRFCYEGFLPAKSKGRRDALKAIE
                     AEPRTLIFYESTHRLLDSLEDIVAVLGESRYVVLARELTKTWETIHGAPVGELLAWVK
                     EDENRRKGEMVLIIEGHKAQEEDLPADALRTLALLQAELPLKKAAALAAEIHGVKKNA
                     LYKYALEQQG"
     gene            6065..8101
                     /gene="lpoA"
                     /locus_tag="RHX21_003382"
     CDS             6065..8101
                     /gene="lpoA"
                     /locus_tag="RHX21_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein activator LpoA"
                     /protein_id="HDV1988528.1"
                     /translation="MVPSTFSRLKAARCLPVVLAALIFAGCGTHTPDQSTAYMQGTAQ
                     ADSAFYLQQMQQSSDDTRINWQLLAIRALVKEGKTGQAVELFNQLPQELNDSQRREKT
                     LLAVEIKLAQKDFAGAQNLLAKITPADLEQNQQARYWQAKIDASQGRPSIDLLRALIA
                     QEPLLGAKEKQQNIDATWQALSSMTQEQANTLVINADENILQGWLDLQRVWFDNRNDP
                     DMMKAGIADWQKRYPNNPGAKMLPTQLVNVKAFKPASTNKIALLLPLNGQAAVFGCTI
                     QQGFEAAKNIGTQPVAAQVAAAPAADVAEQPQPQTVDGVASPAQASVSDLTGEQPAAQ
                     PAPVSTPAATTTAVSAPANPSAELKIYDTSSQPLSQILSQVQQDGASIVVGPLLKNNV
                     EELLKSNTPLNVLALNQPENIENRVNICYFALSPEDEARDAARHIRDQGKQAPLVLIP
                     RSSLGDRVANAFAQEWQKLGGGTVLQQKFGSTSELRAGVNGGSGIALTGTPITPRATT
                     DSGMTTNNPTLQTTPTDDQFTNNGGRVDAVYIVATPGEIAFIKPMIAMRNGSQSGATL
                     YASSRSAQGTAGPDFRLEMEGLQYSEIPMLAGGNLPLMQQALSAVNNDYSLARMYAMG
                     VDAWSLANHFSQMRQVQGFEINGNTGSLTANPDCVINRKLSWLQYQQGQVVPAS"
     gene            8059..8454
                     /locus_tag="RHX21_003383"
     CDS             8059..8454
                     /locus_tag="RHX21_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HDV1988529.1"
                     /translation="MATVPTRSGSPRQLTTKQTGDAWEVQARRWLEGKGLRFVAANVN
                     ERGGEIDLIMREGRTTVFVEVRYRRSALYGGAAASVTRSKQHKLLQTARLWLARHNGS
                     FDTVDCRFDVVAFTGNEVEWIKDAFNDHS"
     gene            8474..9064
                     /gene="diaA"
                     /locus_tag="RHX21_003384"
     CDS             8474..9064
                     /gene="diaA"
                     /locus_tag="RHX21_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001483830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA initiator-associating protein DiaA"
                     /protein_id="HDV1988530.1"
                     /translation="MQERIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKI
                     LCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQ
                     VRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVE
                     IRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDV"
     gene            9074..9649
                     /gene="yraP"
                     /locus_tag="RHX21_003385"
     CDS             9074..9649
                     /gene="yraP"
                     /locus_tag="RHX21_003385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divisome-associated lipoprotein YraP"
                     /protein_id="HDV1988531.1"
                     /translation="MKALSPIAVLISALLLQGCVAAAVVGTAAVGTKAATDPRSVGTQ
                     VDDGTLEVRVNSALSKDEQIKKEARINVTAYQGKVLLVGQSPNAELSARAKQIAMGVD
                     GANEVYNEIRQGQPIGLGEASNDTWITTKVRSQLLTSDLVKSSNVKVTTENGEVFLMG
                     LVTEREAKAAADIASRVSGVKRVTTAFTFIK"
     gene            complement(9763..10803)
                     /locus_tag="RHX21_003386"
     CDS             complement(9763..10803)
                     /locus_tag="RHX21_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDV1988532.1"
                     /translation="MTGQSSSQAATPIQWWKPALFFLVVIAGLWYVKWQPYYGKAFTA
                     AETHSIGKSILAQADANPWQAALDYAMIYFLAVWKAAVLGVILGSLIQVLIPRDWLLR
                     TLGQSRFRGTLLGTLFSLPGMMCTCCAAPVAAGMRRQQVSMGGALAFWMGNPVLNPAT
                     LVFMGFVLGWGFAAIRLVAGLVMVLLIATLVQKWVRETPQTQAPVEIDIPEAQGGFFS
                     RWGRALWTLFWSTIPVYILAVLVLGAARVWLFPHADGAVDNSLMWVMAMAVAGCLFVI
                     PTAAEIPIVQTMMLAGMGTAPALALLMTLPAVSLPSLIMLRKAFPAKALWLTGAMVAV
                     SGVIVGGLALLF"
     gene            complement(10876..11511)
                     /locus_tag="RHX21_003387"
     CDS             complement(10876..11511)
                     /locus_tag="RHX21_003387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417621.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HDV1988533.1"
                     /translation="MSQVLITGATGLVGGHLLRMLINEPKVNAIAAPTRRPLGDMPGV
                     FNPHDPQLSDALAQVTDPIDIVFCCLGTTRREAGSKEAFIHADYTLVVDTALTGRRLG
                     AQHMLVVSAMGANAHSPFFYNRVKGEMEEALIAQNWPKLTIARPSMLLGDRSKQRMNE
                     TLFAPLFRLLPGNWKSIDARDVARVMLAEAMRPGHEGVTILSSSELRKRAE"
     gene            11639..12157
                     /gene="yhbO"
                     /locus_tag="RHX21_003388"
     CDS             11639..12157
                     /gene="yhbO"
                     /locus_tag="RHX21_003388"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417622.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein/nucleic acid deglycase"
                     /protein_id="HDV1988534.1"
                     /translation="MSKKIAVLITDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVK
                     GKKGEASVTIDKSIDEVTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFA
                     ICHGPQLLISADVIRGRKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLP
                     AFNREALRLLGA"
     gene            complement(12137..12580)
                     /locus_tag="RHX21_003389"
     CDS             complement(12137..12580)
                     /locus_tag="RHX21_003389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbP family protein"
                     /protein_id="HDV1988535.1"
                     /translation="METLTAISRWLAKQHVVTWCVQQEGELWCANAFYLFDAQKVAFY
                     ILTEEKTRHAQMSGPQAAVAGTVNGQPKTVALIRGVQFKGEIRRLEGEESDLARKAYN
                     RRFPVARMLSAPVWEIRLDEIKFTDNTLGFGKKMIWLRDSGTEQA"
     gene            12631..12933
                     /gene="yhbQ"
                     /locus_tag="RHX21_003390"
     CDS             12631..12933
                     /gene="yhbQ"
                     /locus_tag="RHX21_003390"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708956.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage response exodeoxyribonuclease YhbQ"
                     /protein_id="HDV1988536.1"
                     /translation="MTPWYLYLIRTADNKLYTGITTDVERRYQQHQSGKGAKALRGKG
                     ELTLAFSAPVGDRSLALRAEYRVKQLTKRQKERLVAEGAGFAELLSSLQTPKIKSD"
     gene            complement(12920..13423)
                     /locus_tag="RHX21_003391"
     CDS             complement(12920..13423)
                     /locus_tag="RHX21_003391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDV1988537.1"
                     /translation="MLIRVEIPIDAPGIDALLRRSFESDAEAKLVHDLREDGFLTLGL
                     VATDDEGQVIGYVAFSPVDVQGEDLQWVGMAPLAVDEKYRGQGLARQLVYEGLDSLNE
                     FGYAAVVTLGDPALYSRFGFELAAHHDLRCRWPGTESAFQVHRLADDALNGVTGLVEY
                     HEHFNRF"
     gene            complement(13417..13941)
                     /locus_tag="RHX21_003392"
     CDS             complement(13417..13941)
                     /locus_tag="RHX21_003392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SCP2 domain-containing protein"
                     /protein_id="HDV1988538.1"
                     /translation="MLDKLRSRIVHLGPSLLSVPIKLTPFALKRQVLEQVLSWQFRQA
                     LDDGELEFLEGRWLSIHVRDIDLQWFTSVVNGKLVVSQNAQADVSFSADASDLLMIAA
                     RKQDPDTLFFQRRLVIEGDTELGLYVKNLMDAIELEQMPKALRMMLLQLADFVEAGMK
                     TAPETKQTSVGEPC"
     gene            14150..15145
                     /locus_tag="RHX21_003393"
     CDS             14150..15145
                     /locus_tag="RHX21_003393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017457364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDV1988539.1"
                     /translation="MELLCPAGNLPALKAAIENGADAVYIGLKDDTNARHFAGLNFTE
                     KKLQEAVSFVHQHRRKLHIAINTFAHPDGYARWQRAVDMAAQLGADALILADLAMLEY
                     AAERYPHIERHVSVQASATNEEAINFYHRHFDVARVVLPRVLSIHQVKQLARVTPVPL
                     EVFAFGSLCIMSEGRCYLSSYLTGESPNTVGACSPARFVRWQQTPQGLESRLNEVLID
                     RYQDGENAGYPTLCKGRYLVDGERYHALEEPTSLNTLELLPELMAANIASVKIEGRQR
                     SPAYVSQVAKVWRQAIDRCKADPQNFIPQSAWMETLGSMSEGTQTTLGAYHRKWQ"
     gene            15154..16032
                     /locus_tag="RHX21_003394"
     CDS             15154..16032
                     /locus_tag="RHX21_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312067.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDV1988540.1"
                     /translation="MKYSLGPVLWYWPKETLEDFYQQAATSSADVIYLGEAVCSKRRA
                     TKVGDWLEMAKSLAGSGKQIVLSTLALVQASSELGELKRYVENGEFLIEASDLGVVNM
                     CAERKLPFVAGHALNCYNAVTLKILLKQGMMRWCMPVELSRDWLVNLLNQCDELGIRN
                     QFEVEVLSYGHLPLAYSARCFTARSEDRPKDECETCCIKYPNGRNVLSQENQQVFVLN
                     GIQTMSGYVYNLGNELASMQGLVDVVRLSPQGTDTFAMLDAFRANENGAAPLPLTANS
                     DCNGYWRRLAGLELQA"
     gene            16238..17245
                     /locus_tag="RHX21_003395"
     CDS             16238..17245
                     /locus_tag="RHX21_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="luciferase-like monooxygenase"
                     /protein_id="HDV1988541.1"
                     /translation="MTDKTIAFSLLDLAPIPEGSSAREAFSHSLDLARLAEKRGYHRY
                     WLAEHHNMTGIASAATSVLIGYLAANTTTLHLGSGGVMLPNHSPLVIAEQFGTLNTLY
                     PGRIDLGLGRAPGSDQRTMMALRRHMSGDIDNFPRDVAELVDWFDARDPNPHVRPVPG
                     YGEKIPVWLLGSSLYSAQLAAQLGLPFAFASHFAPDMLFQALHLYRSNFKPSARLEKP
                     YAMVCINIIAADSNRDAEFLFTSMQQAFVKLRRGETGQLPPPIQNMDQFWSPSEQYGV
                     QQALSMSLVGDKAKVRHGLQSILRETDADEIMVNGQIFDHQARLHSFELAMDVKEELL
                     G"
BASE COUNT         4370 a         4560 c         4364 g         3997 t
ORIGIN      
        1 aaatatttct acctgtataa tctttaaaga tgttgaacat atattcacat taaatatgat
       61 tatgtacttg ttacaaggat aaggttataa atgaataaag ttacaaaaac agctattgtg
      121 ggcttacttg cgcttttcgc aggtaatgcc gctgcaaccg atggtgaaat agtttttgat
      181 ggcgagattt taaaatccgc ttgtgaaatc aatgactctg ataagaaaat tgaagttgct
      241 cttggtcact ataatgccga acagtttcgt tctgttggcg atcgtagccc aaaaattcca
      301 ttcactattc ctttagttaa ctgcccagtg actgggtggg agcacgataa cggcaacgtt
      361 gaagcgtctt tccgtttatg gctggaaacg cgggataatg gcaccgtccc taacttccct
      421 aatctggcaa aagtgggctc ttttgctggc acagcggcaa caggtgtggg tatccgtatt
      481 gacgatgcgg aaagcggaaa ccttatgcca ctgaatgcta tggggaatga taacacggtt
      541 tatcagatcc cagcggactc caatggtatt gtcaatgttg acctcatcgc ttactacgta
      601 tcaaccgttg aagcatcaga aatcacccca ggggaagcag acgctgtcgt taacgtaacg
      661 ctggattacc gttaatacgt tacggcgtta tctgaccttt cagataacgc ccttttcctt
      721 cctctttctc gttgtatcag gttgaaaaat aactatgtca aaacgaacat tcgcggtgat
      781 aataaccttg ttgtgtagct tctgtatcgg ccaggcgctt gcagggggta tcgttttaca
      841 gcgaacgcga gtgatctatg atgccagccg caaagaggct gcgttacctg tcgcaaacaa
      901 aggcgcagaa acgccttatt tactgcaatc atgggtagat aatatagatg gtacaagccg
      961 tgccccattt attataaccc caccgctatt tcgtcttgaa gctggcgatg actcatcact
     1021 gcgaattatt aaaacagctg ataacctgcc tgaaaataaa gagtcgctgt tctacattaa
     1081 tgttcgtgcc attccagcaa agaaaaaatc agatgatgtt aatgctaacg agttgacgct
     1141 ggtatttaaa acacggatca aaatgtttta tcgccccgca cacctgaagg gacgggtaaa
     1201 cgatgcgtgg acatcactgg aatttaaacg tagtgaccat tcactcaata tatataaccc
     1261 aactgaatat tacgtcgtat ttgccggact ggcagtcgat aaaaccgatc tcacaagcaa
     1321 aattgaatat atcgcgcccg gagaacataa acagttacca cttcctgcat ctggcggaaa
     1381 gaacgtgaaa tgggctgcaa tcaatgatta tggcggcagt tccgggacag aaactcgtcc
     1441 actgcaataa caaatataaa aaacacaggt catcagggaa tgccacaacg acaccaccag
     1501 ggacataaac gcacaccgaa acagttggcg ctcatcatca aacgctgttt gccgatggtg
     1561 ctcactggca gcggcatgct ttgcactacc gctaacgccg aagagtatta tttcgacccc
     1621 attatgctgg aaactacaaa aagtggtatg caaacaactg atctgtcacg tttttcaaaa
     1681 aaatacgcac aactaccagg aacttatcag gttgatatct ggctgaataa aaagaaggtt
     1741 tcacagaaaa aaattacatt taccgccaat gcagagcaac ttctgcagcc acagtttacg
     1801 gtagaacaac tacgtgagct gggtattaag gtggatgaaa tcccggcgct ggctgaaaaa
     1861 gatgacgata gcgtgatcaa ctcgcttgaa caaatcattc ccggtacagc tgctgaattt
     1921 gatttcaatc atcagcgact taatttgagc attccccaaa ttgcactgta ccgtgatgca
     1981 aaaggttacg tctccccttc tcgttgggac gatggtatac caacgctgtt taccaactac
     2041 tcgtttacag gttctgataa ccgttaccgc cagggcaatc gtagccaacg acagtacctg
     2101 aatatgcaaa atggtgctaa ttttggcccc tggcgattac gtaactattc tacgtggaca
     2161 cgcaacgatc aggcgtcaag ctggaacact atcagtagtt atttacaacg tgatatcaag
     2221 gcgttgaagt ctcagttgct tctgggagaa agcgccacca gcggcagtat tttttccagc
     2281 tacaccttta ctggcgtgca actcgcttcc gacgataata tgttgccaaa cagccagcgc
     2341 ggatttgccc caacggtacg cggtatcgca aacagtagtg caatcgtgac tatcaggcaa
     2401 aatggttatg tgatctatca aagcaacgtg ccagcgggtg cctttgaaat taacgatctc
     2461 tacccctctt ccaacagcgg cgatttagaa gtcacgattg aagaaagtga cggtacgcaa
     2521 cgtcgcttta tccagcctta ttcttcatta cccatgatgc agcgacctgg gcatctaaaa
     2581 tatagcgcga ccgctggacg ctatcgcgct gatgcaaaca gtgatagcaa ggaacccgaa
     2641 tttgctgaag ccacggcaat atatggtttg aataatactt ttacgctgta tggcggcctg
     2701 ctcggttctg aagattatta tgcgctgggg atcggtatcg gcggcacact tggcgcactg
     2761 ggcgcgttgt cgatggatat caacagagct gacacccaat tcgataaccg gcactctttt
     2821 catggctatc aatggcgtac gcagtacatc aaagatatcc cggaaaccaa caccaatatc
     2881 gctgttagct actatcgcta taccaacgat ggctatttta gttttgatga agccaatacc
     2941 cgtaattggg actataacag tcgccaaaaa agtgaaattc aattcaacat cagccagaca
     3001 atatttgatg gggtaagtct gtatgcctcc ggttcgcagc aagactattg gggcaataac
     3061 gataaaaaca ggaatatctc agttggggtt tccggtcagc aatggggaat tggttacagc
     3121 ctgaattatc aatacagtcg ctacacggat caaaataatg accgcgcact ctctttgaat
     3181 ctcagtattc cgttagaacg ctggttaccg cgtagccggg tttcctatca gatgaccagc
     3241 cagaaagatc gcccaaccca acatgaaatg cgtcttgatg gctcactgct ggatgatggt
     3301 cgcctgagct atagcctgga acaaagtctg gatgacgata acaaccataa cagtagcctg
     3361 aacgccagtt accgttcacc ttatggcacc ttcagtgccg gatacagcta cggtaatgac
     3421 agcagccaat acaattacgg cgttaccggc ggcgtggtta tccatcctca tggcgtgacg
     3481 ctctcgcaat atctgggcaa cgcttttgcg cttatcgatg ctaatggggc ttctggcgtg
     3541 aggatacaaa actatccggg gattgctact gatccctttg gctatgcagt ggttccttat
     3601 ctcacgactt accaggaaaa ccgtctctcg gtagatacta cgcagctgcc cgataacgtc
     3661 gatcttgagc aaacaacaca gtttgtggtg cccaacagag gtgcaatggt agcggcgcgt
     3721 ttcaacgcca atatcggtta tcgcgtactt gttacagtca gcgatcgcaa cggtaaaccg
     3781 ttgcccttta gcgctcttgc cagcaacgat gagacggggc aacaaagtat cgtcgatgag
     3841 ggcggcatac tatatctctc tgggatatcg agtaaatcac aaagctggac tgtacgctgg
     3901 ggaaatcagg cagatcaaca atgtcagttt gcttttagta caccggattc agaaccaaca
     3961 acctctgtat tacaaggcac ggcgcagtgc cattaaggat aaaaaaatga aaagagcgcc
     4021 tcttataaca ggacttttgt tgatatccac atcctgcgct tatgcctcct caggagggtg
     4081 tggagctgac agcactagcg gtgcgacaaa ttacagcagt gtggttgatg atgttacggt
     4141 gaaccagaca gataacgtga caggacggga gtttacctct gccacgctaa gtagcactaa
     4201 ctggcaatac gcctgtacct gctctgcggg taaggcagtt aaacttgtct atatggtcag
     4261 ccctgtactt accaccactg gacatcaagc aggatattac aaactcaatg atagtctgga
     4321 tattaaaacc acattacagg cgaatgacat tccaggactc gtgactgacc agaccgtttc
     4381 tgttaacacc cgattcacac agataaaaag caacaccgta tattctgctg caacccaaac
     4441 gggtgtttgc cagggtgaca cgtctcgtta tggacccgtt aatattggtg caaataccac
     4501 ctttaccctg tatgtcacca agccatttct cggctcgatg accattccga aaacggatat
     4561 tgccgtcatt aaaggcgcat gggtcgatgg aatgggaagc ccgtctacag gtgacttcca
     4621 tgatttagtc aagttatcga ttcagggaaa tctcaccgcc ccacagtcgt gcaaaattaa
     4681 tcagggcgat gttattaagg ttaattttgg attcatcaat ggtcagaagt ttaccacccg
     4741 caatgccatg ccagacggtt ttactccagt agactttaat atcacttatg actgtggtga
     4801 tacttcaaag attaaaaact cgttgcaaat gcgcatcgac ggtacaactg gggtagtaga
     4861 ccagtacaac ctggtcgcca gacgaagaag ttcagacaat gcgcccgatg tcggtattcg
     4921 tattgaaaat ctcggcggcg gagttgcaaa tattcctttt cagaacggta tccttcccgt
     4981 tgatccttcc gggcatggca ccatcaacat gcgcgcctgg ccagttaatc tggtcggtgg
     5041 tgagctggaa acaggaaaat ttcagggcac cgccaccatt accgtcatcg tgcggtaaaa
     5101 gaagacgttg cgttttgatt aacgcaacgc ttcggcactc ttacccctgc tgctccagcg
     5161 catacttata cagcgcattt ttcttcacgc cgtgaatttc tgccgccagc gccgccgctt
     5221 ttttcaacgg cagttctgcc tgtagcagcg ccagcgtgcg cagggcatcg gcgggtaagt
     5281 cttcttcctg tgctttatga ccttcgataa tcagcaccat ttcgcctttg cgacggtttt
     5341 catcttcttt tacccacgcc agcagctcgc caacgggcgc gccgtgaatg gtttcccagg
     5401 ttttggtcag ctcacgcgcc agaaccacgt agcgggattc gcctaatacc gcaacgatat
     5461 cttccaggct atctaacaga cggtgggtgg attcataaaa aatcagcgtg cgcggctccg
     5521 cttcaatggc ttttagcgca tcacggcggc cttttgattt ggcaggtaaa aagccttcgt
     5581 aacagaaacg gtcagagggt aaacccgcgg cgcttaacgc agtgatagca gcacacggcc
     5641 cgggtagcgg caccacgcaa atccccgctt cacggcaggt acgcaccaga tggtagccag
     5701 gatcgttaat tagcggcgtt ccggcatcgg aaaccagcgc aatgttctgc ccttcttgca
     5761 gcttcgccag cagcgtttcg gctttttgtt gttcgttatg gtcgtgcagc gcaaacaacc
     5821 gggcattaat cccaaaatgt tgcagcaata aaccggtgtg acgagtatcc tcggcggcaa
     5881 tcagatcaac ggcctgtaat acctctaacg cacgctgggt gatatccgcc agattgccga
     5941 ttggcgtcgg tacaatgtaa agctggccct gagaattatc cgccgattgg tgttgtttca
     6001 ttgtgtcgtc cgtattgccg atttaatatt gagcattgcg taaaaaaata tcactggata
     6061 cattatggta ccctcaacat tttctcgttt gaaagccgcg cgttgtctgc ctgttgttct
     6121 ggcagccctg attttcgccg gttgtggcac ccatactccc gatcagtcca ctgcttatat
     6181 gcagggcacg gcgcaggctg attctgcctt ttatcttcag cagatgcagc aaagctctga
     6241 tgataccagg atcaactggc aattactcgc cattcgtgca ctggtgaaag aaggtaaaac
     6301 cgggcaggcg gttgagttgt ttaaccaact accgcaagaa ctgaacgatt ctcagcgtcg
     6361 cgagaaaaca ctgctggcgg tagagattaa actggcgcag aaagattttg ctggcgcgca
     6421 aaacttgctg gcgaaaatca cacctgccga tttagaacaa aaccagcaag cgcgttactg
     6481 gcaggcaaaa atcgatgcca gccaggggcg tccttccatt gatttactgc gcgcgttaat
     6541 tgctcaggaa ccgctgctcg gcgcgaaaga aaaacagcag aatattgatg ccacctggca
     6601 ggcgctctcc tccatgactc aggaacaggc gaatacgctg gtgatcaacg ccgacgaaaa
     6661 tattctgcaa ggctggctgg atctgcagcg cgtctggttt gataaccgta acgatcccga
     6721 catgatgaaa gccgggatcg ccgactggca aaaacgttat ccgaacaatc cgggcgcgaa
     6781 aatgctgcca acgcagttgg ttaacgtaaa agcgtttaaa ccagcctcga ccaacaaaat
     6841 cgccctgctg ttgccgctga atggccaggc agcggtattt ggttgcacta ttcagcaagg
     6901 ctttgaagcg gcgaaaaata tcggcactca gccagtggcg gctcaggtag ctgccgcacc
     6961 tgccgcagac gtagctgaac aacctcagcc gcaaaccgtg gatggcgttg ccagcccggc
     7021 acaagcctcg gttagcgatc tgaccggtga acagcctgcg gcacagccag cgcctgtaag
     7081 caccccggca gcaaccacca cagcggtaag cgcgccagcg aatccatccg cagaactgaa
     7141 aatctacgat acctcatcac aaccacttag ccagatctta agccaggttc agcaggatgg
     7201 cgcgagtatt gtggttggtc cgttgctgaa aaataacgtt gaagagttgc ttaagagcaa
     7261 caccccgctg aacgtgctgg cactgaacca gccggagaat atcgaaaacc gcgtcaatat
     7321 ttgttacttc gcgctttcac cggaagacga agcgcgcgat gcagcgcgtc atattcgtga
     7381 ccagggtaaa caagcgccgc tggtgctgat cccacgcagt tcattgggcg atcgcgtagc
     7441 caatgcgttt gcgcaggagt ggcagaaact gggcggcggc accgttctgc aacaaaaatt
     7501 tggttccacc agcgaattac gcgcgggtgt taacggcggt tctggtatcg ctttaacggg
     7561 taccccgatt actcccagag cgacaaccga ctccggcatg acgaccaaca atccaacgct
     7621 gcaaaccacg ccaaccgatg accagttcac caataatggc ggtcgtgtcg atgcggtgta
     7681 cattgtggca acgccgggtg aaatcgcttt tatcaaaccg atgatcgcca tgcgtaacgg
     7741 tagccagagc ggtgcaacgc tgtacgccag ctcccgcagt gcgcaaggga ccgctggccc
     7801 ggatttccga ctggagatgg aaggcttgca gtacagcgaa atcccgatgc tggcaggcgg
     7861 taatctaccg ttaatgcagc aggcactcag cgcggtgaat aacgattatt cactggctcg
     7921 catgtatgcg atgggcgtcg atgcctggtc gctggcaaat catttctcac aaatgcgcca
     7981 ggttcagggt tttgaaatca acggtaatac cggaagcctg acggcaaacc cggattgcgt
     8041 gattaacagg aagttatcat ggctacagta ccaacaaggt caggtagtcc ccgccagtta
     8101 accaccaaac agaccggcga tgcgtgggaa gtacaagcgc gtcgctggct ggaaggcaaa
     8161 ggactgcgat ttgtcgccgc taacgtgaac gagcgtggcg gcgagatcga tctgataatg
     8221 cgtgaaggcc ggaccaccgt ttttgtcgag gtacgctatc gccgctctgc gctttatggc
     8281 ggcgcggcag ccagtgtgac ccgcagcaaa caacacaaat tattacagac tgcccgcttg
     8341 tggctcgcgc gtcataatgg gagttttgat actgtggatt gccggttcga tgtggtagcc
     8401 ttcaccggga atgaggttga gtggattaag gatgccttta atgaccactc ataattaagg
     8461 tttaaggatt agcgtgcaag aaagaattaa agcttgcttc actgaaagca ttcaaactca
     8521 aattgcggcg gcagaggcgc ttccggatgc catctcccgt gcagccatga cgctggttca
     8581 gtctctgctc aatggcaaca aaatcctctg ttgtggtaat ggaacttccg ctgccaatgc
     8641 acagcatttt gctgccagca tgatcaaccg tttcgaaacg gagcggccca gcttacctgc
     8701 cattgcacta aatactgata atgttgtctt aacggcgatt gccaacgatc gcttacatga
     8761 tgaagtgtat gcaaaacagg tgcgggcgct gggtcatgcg ggagatgtat tgttagccat
     8821 ttccacccgt ggcaacagcc gcgatattgt aaaagcggta gaagctgccg ttacgcgtga
     8881 tatgactatt gtggcattga ccggctatga cggcggcgaa cttgcaggtt tgttagggcc
     8941 acaagatgtg gagatccgca ttccttcgca tcgtagtgct cgcattcagg aaatgcatat
     9001 gctgacggta aattgcctgt gcgatctgat cgataacacg cttttccctc accaggatgt
     9061 ttaaggagaa tacatgaagg cattatcgcc aatcgcagtc cttatttccg cgctgctgtt
     9121 gcaaggttgt gttgccgctg ccgtagtggg taccgctgct gtgggtacca aagccgcaac
     9181 tgacccacgc agtgtcggca cccaggtgga cgatggtacc ctggaagtgc gcgtgaacag
     9241 cgcattgtcg aaagacgaac agattaagaa agaagcccgt attaatgtca cggcgtatca
     9301 gggcaaagtg ctgctggttg ggcagtcacc aaacgctgaa ctttcggctc gcgccaaaca
     9361 gattgctatg ggcgtagacg gtgccaacga agtgtataac gagattcgtc agggccagcc
     9421 gattggtctg ggcgaagcgt ctaacgatac gtggatcacc accaaagtgc gttcgcagct
     9481 cttaaccagc gacctggtga aatcgtccaa cgtgaaagtg accaccgaaa acggtgaagt
     9541 gttcctgatg gggctggtga ctgaacgtga agcgaaagcg gcggcagata ttgccagccg
     9601 ggtgagcggc gtaaagcggg taaccacagc gtttacgttt attaaatagc agccccttgt
     9661 aatgcctgat gcgacgcttg ccgcgtctta tcaggcctac aacgatgcaa accgtaggtc
     9721 ggataaggcg tttacgccgc atccgacatg ttttccctca aatcagaaca acagcgccag
     9781 cccgccgaca atcacaccag acactgccac catcgcccct gtcagccata aggctttcgc
     9841 tgggaacgct ttgcgcagca taatcagtga cggcaaactc accgccggga gcgtcatcaa
     9901 caatgccagc gccggagcag ttcccatacc tgccagcatc atcgtttgta caatcggaat
     9961 ttctgctgcc gtgggaatga caaacaagca tcctgctacc gccatcgcca tcacccacat
    10021 caggctgtta tcgacagcac catcggcatg ggggaataac cagacgcgag cggcacccaa
    10081 caccagtact gcaaggatgt aaaccgggat cgtactccag aaaagcgtcc atagcgccct
    10141 gccccagcgg ctaaaaaaac cgccctgtgc ttccggtatg tcaatttcga ccggtgcctg
    10201 cgtttgcggt gtttcacgca cccatttttg caccagcgtc gcaatcagca acaccatcac
    10261 cagcccggcc accagacgaa tcgccgcaaa accccagccg aggacaaacc ccataaacac
    10321 cagcgtcgcc gggtttaaca ccggattgcc catccagaat gccagcgcac cgcccatcga
    10381 cacctgttgg cgacgcattc ccgccgcgac cggagccgca cagcaggtac acatcatgcc
    10441 cggcagcgaa aacagcgttc ccagcagcgt gccgcgaaag cgcgattgcc caagcgtacg
    10501 caacaaccag tcacgcggga tcagcacctg aatcaacgaa ccgaggatca cccccagcac
    10561 tgccgctttc cataccgcga ggaaatagat catcgcgtaa tccaacgccg cctgccacgg
    10621 attagcatcc gcctgcgcaa ggatagattt accgatactg tgggtttcgg cagcagtaaa
    10681 cgctttgccg tagtaaggtt gccatttcac ataccagaga ccggcaatga caacgagaaa
    10741 gaaaagcgcg ggtttccacc actgaatggg cgttgccgcc tgagatgaag actgaccagt
    10801 catagcattc cccaggaata agttatgata attgagcgcg tgaatattac gctcactatc
    10861 aattcttggg aataattatt cagctctttt gcgtaattct gaagagctta aaatcgtcac
    10921 accttcatgc ccgggccgca tcgcctctgc cagcatgacc cgcgccacgt ctctcgcatc
    10981 aatggatttc cagttaccgg gtaataaacg gaacagcggc gcaaaaagcg tttcgttcat
    11041 ccgctgtttg ctacgatcgc ccagtaacat cgacgggcga gcaatggtca atttcggcca
    11101 gttctgggcg attaatgctt cttccatctc ccctttgacg cggttataga aaaacggcga
    11161 gtgggcattg gcacccatag cactgaccac cagcatatgc tgcgcgccca gtcgccgccc
    11221 ggttaatgcg gtatccacta ccagcgtgta atcggcatga ataaacgcct ctttgctccc
    11281 cgcttctcgc cgcgtggtgc cgagacaaca aaacacaatg tcgatgggat cggtgacctg
    11341 cgccagcgcg tcactcagtt gcggatcatg gggattaaac accccgggca tatcgcccaa
    11401 cggacgtcgc gtcggcgcag caatggcgtt aactttcggt tcgttaatca acatccgcag
    11461 caggtgaccg cccaccagcc ccgttgcgcc tgtaatcagt acctgactca tcttcgctcc
    11521 tttacagaat tgtctgcctt gcgctccacg gctcatgcac caggcttaat agaccatgag
    11581 gtaattatcc ccgattgtgg gaaattcgcc tcatccaatg caacaacgcg gaggaagcat
    11641 gagtaagaaa attgccgttt taatcactga tgaatttgag gattcagaat ttacttcacc
    11701 cgcagacgag ttccgtaaag ccggacacga agtgattacc attgaaaaac aagcgggtaa
    11761 aacggtgaaa ggcaaaaaag gagaagccag cgtgaccatc gataaatcca tcgatgaagt
    11821 gacgcctgcg gagtttgatg ccctgctgct accgggcggc cattcaccgg attatctgcg
    11881 tggggacaac cgttttgtca cctttacccg tgattttgtg aatagtggca aaccggtgtt
    11941 tgccatctgt cacggcccgc agttgctgat cagcgccgat gtgattcggg ggcgcaagct
    12001 gaccgcagtt aaaccgatca ttattgatgt taaaaatgcg ggcgcggaat tttacgatca
    12061 ggaagttgtg gttgataaag atcagctggt taccagccgg acaccggacg atctgccagc
    12121 gtttaaccgc gaggcgttac gcctgctcgg tgcctgagtc gcgtagccaa atcatttttt
    12181 taccaaagcc cagcgtgttg tcggtgaatt tgatttcatc gagccggatt tcccataccg
    12241 gggccgacag cattctggca accggaaagc gacggttgta cgccttgcgt gcgaggtcgc
    12301 tttcctcacc ttccagcctg cggatctcac ctttaaactg cacaccgcga attaacgcta
    12361 ctgttttcgg ctgaccgttt accgttccgg caactgccgc ctgcggccca ctcatctgcg
    12421 catgacgtgt tttttcttcc gtcaaaatgt agaaggcgac tttctgtgca tcaaaaagat
    12481 aaaaggcatt ggcgcaccag agttcccctt cctgctgcac acaccaggtg acaacatgtt
    12541 gttttgccag ccaacgactg atggcggtga gtgtttccat tgctgttctc ttttatactg
    12601 ttggcctgac cttaacatgt gacgcagacg atgacaccct ggtatcttta cttgatccgt
    12661 accgccgaca ataagcttta taccgggatc accacggatg tcgaacgccg ctatcagcaa
    12721 catcaaagcg gcaaaggggc gaaagcactg cgcgggaaag gagaactgac gctggcgttt
    12781 tctgcgccag tgggcgatcg ttcgctggcg ttacgggcag aatatcgcgt taagcaactg
    12841 accaaacggc aaaaagagcg tctggtagcg gaaggcgcag ggtttgcaga gctgttgagc
    12901 agcctgcaaa ccccaaagat taaaagcgat tgaaatgctc gtgatactca accaggccgg
    12961 taacgccatt cagcgcgtca tccgctaaac gatgtacctg gaaggcgctt tcagtgcccg
    13021 gccagcggca acgcagatcg tgatgcgccg ccagttcaaa gccgaaacga ctgtacagcg
    13081 ccggatcgcc cagcgtcacc actgcggcat agccgaactc attaagcgaa tcgagtcctt
    13141 catagaccag ttggcgtgcc agcccctgtc cacggtattt ttcatcaacc gccaacggtg
    13201 ccatgccgac ccattgcagg tcttcgccct gcacatcaac cggactaaat gccacatagc
    13261 caatgacctg accttcgtca tctgtcgcca ccagccccag cgtcagaaag ccatcttcac
    13321 gcagatcgtg aaccagcttc gcttccgcat cactttcgaa tgagcgacgc agcagggcat
    13381 caatacccgg cgcatcaatg ggaatttcta ctcgaattag catggttcac ctaccgatgt
    13441 ctgtttggtt tcaggcgcgg ttttcattcc cgcctcaaca aaatccgcca gttgcagcag
    13501 catcatgcgt aaggctttcg gcatttgctc cagttcaatg gcgtccatca ggtttttcac
    13561 atacagcccc agctccgtat cgccttcaat caccagccga cgctggaaga agagcgtatc
    13621 cggatcttgt ttacgcgccg caatcatcag cagatcgctg gcgtcggcac taaaactcac
    13681 atcagcttgc gcgttctggc tgaccaccag tttgccattc accaccgagg taaaccattg
    13741 caggtcaata tcacgcacat gaatacttaa ccagcggcct tcaagaaact ccagctcacc
    13801 atcatccagc gcctgacgga attgccagct taagacctgc tcaagaacct ggcgttttag
    13861 cgcaaatggc gtcagtttta tcggtacact caacagagat ggccccaaat gcacaatacg
    13921 ggaacgcagt ttatccaaca cgagttttac tccctgtttc aacaatcatc ctattttgcc
    13981 atatcagaaa aataacatag cggtataaat caacaattcc atatgaaatt gctgctacca
    14041 ccaatacaac tttaactgcc ttaaatcaaa aattgtcgca gcaaggttaa ctaaaatccc
    14101 agttcgttaa catttttgcg ttttgatagc gcaaccttca ggaaaaatta tggagctgct
    14161 ctgccctgcc ggaaatctcc cggcgcttaa ggcggccatc gaaaacggcg cagatgctgt
    14221 ttatatcggg ctaaaagatg ataccaatgc ccgtcacttc gccggcctta actttaccga
    14281 gaaaaaattg caggaagcgg tgagttttgt ccatcaacat cgccgcaaac ttcacatcgc
    14341 gattaacact tttgcgcatc cggacggtta cgcccgttgg cagcgcgccg tggatatggc
    14401 ggcgcagctg ggtgccgacg cgctgatcct cgccgacctc gccatgctgg aatacgccgc
    14461 cgagcgttat ccgcatattg agcgccacgt atcggtgcag gcttcggcga ccaatgaaga
    14521 ggcgattaac ttttatcatc gccattttga cgttgcccgc gtggtgctgc cgcgcgtgtt
    14581 gtcgattcat caggtgaaac agctggcacg ggtcacacct gtaccactgg aagtgtttgc
    14641 tttcggcagc ctgtgcatta tgtcggaagg ccgttgctat ctgtcgtcgt atctgacggg
    14701 tgagtcgcct aacaccgtgg gcgcgtgttc tccggcccgt ttcgtgcgct ggcaacaaac
    14761 gccgcagggg ctggaatccc gcctgaacga agtgctgatc gaccgttatc aggacggcga
    14821 aaacgcaggt tatccgacgc tgtgtaaagg gcgttatctg gtggacggcg agcgctatca
    14881 cgcgctggaa gaaccaacca gtctcaatac cctggaactg ctgccggagt taatggcggc
    14941 gaatattgct tcggtgaaaa ttgaaggccg ccagcgtagc ccggcgtatg tcagccaggt
    15001 ggcgaaagtc tggcgtcagg ctatcgaccg ttgtaaggcc gatccgcaaa acttcatacc
    15061 gcaaagcgcg tggatggaga cgctcgggtc gatgtccgaa ggcacgcaga ccacccttgg
    15121 cgcgtatcac cgtaaatggc agtgagaaga gcaatgaaat attccttagg gccagtgctg
    15181 tggtactggc caaaagagac gctggaagat ttttatcagc aggccgccac cagcagcgcc
    15241 gacgtgattt atcttggtga agcggtatgc agcaagcgcc gggcaaccaa agttggcgac
    15301 tggctggaga tggcaaaatc gctcgccgga agtggcaagc agattgtgct ctccacgctg
    15361 gcgctggtgc aggcatcctc tgaactgggc gaactgaaac gctatgttga gaacggtgag
    15421 tttctgattg aagccagcga tctcggcgtg gtgaatatgt gcgctgaacg caaactgccg
    15481 ttcgtcgccg ggcacgcgct gaactgctac aacgcggtga cgctgaaaat attgctcaaa
    15541 cagggcatga tgcgctggtg tatgccggtg gagctttccc gcgactggct ggtgaatctg
    15601 cttaatcagt gcgatgagct gggcattcgc aaccagtttg aagtggaagt cctgagctac
    15661 ggtcatctac cgctggccta ctccgcccgc tgctttaccg cgcgttcgga agaccgcccg
    15721 aaagatgagt gtgaaacctg ctgcattaag tatccgaacg ggcgcaacgt gctgtcgcag
    15781 gaaaaccaac aagtgtttgt actcaatggc attcagacca tgagcggcta cgtttacaac
    15841 ctcggtaacg agctggcatc catgcagggg ctggttgatg tggtccgcct gtcaccgcag
    15901 ggtactgaca ctttcgcgat gctcgacgcc ttccgcgcta atgaaaatgg cgctgcgcca
    15961 ctaccgttga cggcaaacag cgactgtaac ggctactggc ggcggctagc cgggctggag
    16021 ctgcaagcct aagtaaatat gctcgtcata cttcaagttg catgtgctgc atctgcattc
    16081 gttcacccca gtcacttact tatgtaagct cctggggatt cactctcttg tcgccttcct
    16141 gcaactcgaa ttatttagag cacagctcac tttgttaaca actttaacta ctctttaatg
    16201 cagtattaaa gattaatcgg taacaaagtg agctgttatg actgataaaa ccattgcgtt
    16261 ttcgctactc gatctggccc ccattcccga aggttcttca gcgcgggaag cattctccca
    16321 ctctctcgat ctcgcccgtc tggctgaaaa gcgcggctat catcgctact ggctggcaga
    16381 acaccacaat atgactggca ttgccagtgc tgccacgtcg gtattgattg gctatctggc
    16441 ggcgaatacc accacgctgc atctggggtc tggcggcgtg atgttgccta accactcacc
    16501 gttggtcatt gccgaacagt tcggcacgct caatacactc tatccggggc gaatcgattt
    16561 ggggctgggt cgtgcgccag gtagtgacca acggacaatg atggcgctgc gtcgccatat
    16621 gagcggcgat attgataatt tcccccgcga tgtcgcggag ctggtggact ggtttgacgc
    16681 ccgcgatccc aatccgcatg tgcgcccggt accaggctat ggcgagaaaa tccccgtgtg
    16741 gttgttaggc tccagccttt acagcgcgca actggcggcg cagcttggtc tgccgttcgc
    16801 gtttgcctca cacttcgcgc cggatatgtt gttccaggcg ctgcatcttt atcgcagcaa
    16861 cttcaaaccg tcggcacgac tggaaaaacc atacgcgatg gtgtgcatca atattatcgc
    16921 cgccgatagc aaccgcgacg ctgagtttct gtttacctca atgcagcaag cctttgtgaa
    16981 gttgcgccgt ggcgaaaccg ggcaactgcc gccaccgatt caaaatatgg atcagttctg
    17041 gtcgccgtcc gaacagtatg gtgtgcagca ggcgctgagt atgtcgttgg taggtgataa
    17101 agcgaaagtg cgtcatggct tgcagtcgat cctgcgcgaa accgacgccg atgagattat
    17161 ggtcaacggg cagattttcg accaccaggc gcggctgcat tcgtttgagc tggcgatgga
    17221 tgttaaggaa gagttgttgg gatagtgtgt cttaacgcgg gaagccttat ccgagctggc
    17281 aacgctgtcc t
//
LOCUS       DAPGUL010000096        17214 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.098, whole genome shotgun sequence.
ACCESSION   DAPGUL010000096 DAPGUL010000000
VERSION     DAPGUL010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17214
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.098"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..857
                     /locus_tag="RHX21_003396"
     CDS             <1..857
                     /locus_tag="RHX21_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YjeJ family protein"
                     /protein_id="HDV1988542.1"
                     /translation="KGVNTGVIRKSNNFIALALKIKEPRNKESLFFMSVMELRDLLIA
                     LESRMHQKHKLDAAARLQYEQARDKVIKKMAENIPEILVDELKNADINRRVNTLELTD
                     NQGENLTFVLTLHDGSKCELVVNELQIEMLARAIIHAINNAEMRELALRITSLLDFLP
                     LYDVDCQENGNLEYDTYSQPEWKHNLFDHYLAVLYRFKDESGKEQFSGAVVKTREATP
                     GKEIEAITRRMLDFSQRLKKLAGVPCQVYVRTVAANNAQPLTQDQCLRALHHLRVQST
                     SKTAPQAK"
     gene            complement(1060..1413)
                     /locus_tag="RHX21_003397"
     CDS             complement(1060..1413)
                     /locus_tag="RHX21_003397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4156 domain-containing protein"
                     /protein_id="HDV1988543.1"
                     /translation="MHVKYLAGIVGAALLMAGCSSSNELSAAGQSVRIVDEQPGAECQ
                     LIGTATGKQSNWLSGQHGEEGGSMRGAANDLRNQAAAMGGNVIYGISSPSQGMLSSFV
                     PTDSQIIGQVYKCPN"
     gene            complement(1551..3197)
                     /gene="groL"
                     /locus_tag="RHX21_003398"
     CDS             complement(1551..3197)
                     /gene="groL"
                     /locus_tag="RHX21_003398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120975.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HDV1988544.1"
                     /translation="MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSF
                     GAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITE
                     GLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGK
                     LIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESP
                     FILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAV
                     KAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIID
                     GVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEK
                     KARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAP
                     LRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAA
                     SVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM"
     gene            complement(3241..3534)
                     /locus_tag="RHX21_003399"
     CDS             complement(3241..3534)
                     /locus_tag="RHX21_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000027827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HDV1988545.1"
                     /translation="MNIRPLHDRVIVKRKEVETKSAGGIVLTGSAAAKSTRGEVLAVG
                     NGRILENGEVKPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA"
     gene            3810..5066
                     /gene="yjeH"
                     /locus_tag="RHX21_003400"
     CDS             3810..5066
                     /gene="yjeH"
                     /locus_tag="RHX21_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine/branched-chain amino acid
                     transporter"
                     /protein_id="HDV1988546.1"
                     /translation="MSGLKQELGLAQGIGLLSTSLLGTGVFAVPALAALVAGNNSLWA
                     WPVLIILVFPIAIVFAILGRHYPSAGGVAHFVGMAFGSRLERVTGWLFLSVIPVGLPA
                     ALQIAAGFGQAMFGWHSWQLLLAELGTLALVWYIGTRGASSSANLQTVIAGLIVALIV
                     AIWWAGDIKPANIPFPAPGNIELTGLFAALSVMFWCFVGLEAFAHLASEFKNPERDFP
                     RALMIGLLLAGLVYWGCTVVVLHFDAYGEKMAAAASLPKIVVQLFGVGALWIACVIGY
                     LACFASLNIYIQSFARLVWSQAQHNPDHYLARLSSRHIPNNALNAVLGCCVVSTLVIH
                     ALEINLDALIIYANGIFIMIYLLCMLAGCKLLQGRYRLLAVVGGLLCVLLLAMVGWKS
                     LYALIMLAGLWLLLPKRKTPENGITT"
     gene            complement(5082..5558)
                     /gene="fxsA"
                     /locus_tag="RHX21_003401"
     CDS             complement(5082..5558)
                     /gene="fxsA"
                     /locus_tag="RHX21_003401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418564.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein FxsA"
                     /protein_id="HDV1988547.1"
                     /translation="MRWLPFIAIFLYVYIEISIFIQVAHVLGVLLTLVLVIFTSVIGM
                     SLVRNQGFKNFVLMQQKMAAGENPAAEMIKSVSLIIAGLLLLLPGFFTDFLGLLLLLP
                     PVQKHLTVKLMPHLRFSRMPGGGFSAGTGGGNTFDGEYQRKDDERDRLDHKDDRQD"
     gene            5895..7331
                     /gene="aspA"
                     /locus_tag="RHX21_003402"
     CDS             5895..7331
                     /gene="aspA"
                     /locus_tag="RHX21_003402"
                     /EC_number="4.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313147.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate ammonia-lyase"
                     /protein_id="HDV1988548.1"
                     /translation="MSNNIRIEEDLLGTREVPADAYYGVHTLRAIENFYISNNKISDI
                     PEFVRGMVMVKKAAAMANKELQTIPKSVANAIIAACDEVLNNGKCMDQFPVDVYQGGA
                     GTSVNMNTNEVLANIGLELMGHQKGEYQYLNPNDHVNKCQSTNDAYPTGFRIAVYSSL
                     IKLVDAINQLREGFERKAVEFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKNI
                     QRTAELLLEVNLGATAIGTGLNTPKEYSPLAVKKLAEVTGFPCVPAEDLIEATSDCGA
                     YVMVHGALKRLAVKMSKICNDLRLLSSGPRAGLNEINLPELQAGSSIMPAKVNPVVPE
                     VVNQVCFKVIGNDTTVTMAAEAGQLQLNVMEPVIGQAMFESVHILTNACYNLLEKCIN
                     GITANKEVCEGYVYNSIGIVTYLNPFIGHHNGDIVGKICAETGKSVREVVLERGLLTE
                     AELDDIFSVQNLMHPAYKAKRYTDESEQ"
     gene            7449..8750
                     /gene="dcuA"
                     /locus_tag="RHX21_003403"
     CDS             7449..8750
                     /gene="dcuA"
                     /locus_tag="RHX21_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuA"
                     /protein_id="HDV1988549.1"
                     /translation="MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGN
                     IPFDVISIIMAVIAAISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFA
                     GTGNISLATLPVIAEVAKEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGH
                     GISYLHLLSVVIPSTLLAVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIE
                     IKSGAKTSVWLFLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVI
                     CKVDTDNILNSSTFKAGMSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLA
                     VIFFFASALLYSQAATAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQ
                     MDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFGFVLGSFML"
     gene            8866..9204
                     /gene="cutA"
                     /locus_tag="RHX21_003404"
     CDS             8866..9204
                     /gene="cutA"
                     /locus_tag="RHX21_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent cation tolerance protein CutA"
                     /protein_id="HDV1988550.1"
                     /translation="MLDEKSSNTASVVVLCTAPDEATAQDLAAKVLAEKLAACATLIP
                     GATSLYYWEGKLEQEYEVQMILKTTVSHQQALLECLKSHHPYQTPELLVLPVTHGDTD
                     YLSWLNASLR"
     gene            9180..10877
                     /gene="dsbD"
                     /locus_tag="RHX21_003405"
     CDS             9180..10877
                     /gene="dsbD"
                     /locus_tag="RHX21_003405"
                     /EC_number="1.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide reductase DsbD"
                     /protein_id="HDV1988551.1"
                     /translation="MAQRIFTLILLLCSTSVFAGLFDAPGRSQFVPADQAFTFDFQQN
                     QHDLNLTWQIKDGYYLYRKQIRITPEHAKIADVQLPQGVWHEDEFYGKSEIYRDRLTL
                     PVTINQASAGATLTVTYQGCADAGFCYPPETKTVPLSEVVANNAASQPVSVSQQEQHT
                     AQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGKQRLSTARALLLTFIYVQGMA
                     LTYTALGLVVAAAGLQFQAALQHPYVLIGLAIVFTLLAMSMFGLFTLQLPSSLQTRLT
                     LMSNRQQGGSPGGVFVMGAIAGLICSPCTTAPLSAILLYIAQSGNMWLGGGTLYLYAL
                     GMGLPLMLITVFGNRLLPKSGPWMEQVKTAFGFVILALPVFLLERVIGDVWGLRLWSA
                     LGVAFFGWAFITSLQAKRGWMRVVQIILLAAALVSVRPLQDWAFGATHTAQTQTHLNF
                     TQIKTVDELNQALVEAKGKPVMLDLYADWCVACKEFEKYTFSDPQVQKALADTVLLQA
                     NVTANDAQDVALLKHLNVLGLPTILFFDGQGQEHPQARVTGFMDAETFSAHLRDRQP"
     gene            10914..11489
                     /locus_tag="RHX21_003406"
     CDS             10914..11489
                     /locus_tag="RHX21_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDV1988552.1"
                     /translation="MQREDVLGEALKLLELQGIANTTLEMVAERVDYPLDELRRFWPD
                     KEAILYDALRYLSQQIDVWRRQLMLDETQTAEQKLLARYQALSECVKNNRYPGCLFIA
                     ACTFYPDPGHPIHQLADQQKSAAYDFTHELLTTLEVDDPAMVAKQMELVLEGCLSRML
                     VNRSQADVDTAHRLAEDILRFARCRQGGALT"
     gene            11596..11671
                     /locus_tag="RHX21_003407"
     tRNA            11596..11671
                     /locus_tag="RHX21_003407"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11629..11631,aa:Phe,seq:gaa)
     gene            11869..13134
                     /locus_tag="RHX21_003408"
     CDS             11869..13134
                     /locus_tag="RHX21_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
                     /protein_id="HDV1988553.1"
                     /translation="MALTDAKIRAAKPTDKAYKLTDGAGMFLLVHPNGSRYWRLRYRI
                     LGKEKTLALGVYPEVSLSEARTKRDEARKLISEGIDPCEQKRVKKVVPDLQLSFEHIA
                     RRWHASNKQWAQSHSDKVLKSLETHVFPFIGNRDITTLNTPDLLIPVRAAEAKQIYEI
                     ASRLQQRISAVMRYAVQSGIIRYNPALDMAGALTSVKRQHRPALDLSRLPELLSRINS
                     YKGQPVTRLAVMLNLLVFIRSSELRYARWAEIDIDNSMWTIPAERKPLPGVKFSHRGS
                     KMRTPHLVPLSKQAVAILTELQTWAGENGLIFTGAHDPRKPISENTVNKALRVMGYDT
                     TKEVCGHGFRAMACSALIESGLWSRDAVERQMSHQERNGVRAAYIHKAEHLEERRLML
                     QWWADFLDANREECISPFEYAKVNNPLKR"
     gene            13390..14433
                     /locus_tag="RHX21_003409"
     CDS             13390..14433
                     /locus_tag="RHX21_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDV1988554.1"
                     /translation="MTGKLRFEVNDNQGCFIFPETWFGSLLDEFEELIDAYDADEISE
                     TSYINKLRRLARQENDFIDVHAHLAYVFLEQNAPRKALNAALKGLAVGNRLIPEGFSG
                     RIIWIHPDNRPFLRALYAAILANAHLQRHQDAIMLIEKILDYNPEDNHGARWLLGPEL
                     LRTGAHEQARHILQEHADEFSPYWYELGLLHFLNGELVKAATAFRRGFAANTYIAEIL
                     CGNLHPFPLAVWHNFSGGPDTAEDYYATYHPLWGQYPEALLFVNWLYNHSSVLHERAE
                     IIKCAEMLMQEDDFEICESILRQQEKLRERIDETLSEKIVQKCRNMNGEYVWPWILPF
                     SAAGMKHTGIQYQ"
     gene            complement(14793..16295)
                     /locus_tag="RHX21_003410"
     CDS             complement(14793..16295)
                     /locus_tag="RHX21_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001608786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HDV1988555.1"
                     /translation="MNIRKLFCPGNTPRILLFLFFFVVSAITTIACGYTEKNATGNVL
                     LLFLLLLLAHRNTLTSITALLFLFCCALYAPAGMTYGKINNSFIVALLQTTTDEAAEF
                     TGMIPVYHFLVSAAILVFMVIFWRTHHRGHRNWLALLLFVLCSVNSWPLRMVKGTVVG
                     TTDTLREMQRYKQLNQHGADNWKILPGVPLYDTIVIVTGESVRRDYMSVYGYPVPTTP
                     WLNTAPGLFIDGYTSAAASTVPSLSRTLIYDYEQNPDSGNNVVALAAKAGYSTWWISN
                     QGKLGEHDTRISVIASDAEHTVFLKKGSFASRKTDDMLLLQETERALADKSSPKVIFL
                     HMMGSHPNPCDRLHSWPNHYLEQYPRKVACYLASISKLDNFLGQLDGILRRHSRHFVM
                     LYFSDHGLSVSDSANPVHHDGHVQGGYSVPLIITASDITSHQSVSRKISARHFAGIFQ
                     WLTGIRTENIPPFNLLTDEDNEPIMVFNGERNVPADSLKPQPLILPVKGK"
     gene            complement(16477..17193)
                     /locus_tag="RHX21_003411"
     CDS             complement(16477..17193)
                     /locus_tag="RHX21_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin family protein"
                     /protein_id="HDV1988556.1"
                     /translation="MVVAACVFAANAGAKEGKSGFYLTGKAGASVVSLSDQRFLSGDE
                     EETSKYKGGDDHDTVFSGGIAAGYDFYPQFSIPVRTELEFYARGKADSKYNVDKDSWS
                     GGYWRDDLKNEVSVNTLMLNAYYDFRNDSAFTPWVSAGIGYARIHQKTTGISTWDYEY
                     GSSGRESLSRSGSADNFAWSLGAGVRYDVTPDIALDLSYRYLDAGDSSVSYKDEWGDK
                     YKSEVDVKSHDIMLGMTYNF"
BASE COUNT         4339 a         4354 c         4132 g         4389 t
ORIGIN      
        1 tcaagggtgt taataccggt gttattcgca agagtaataa tttcattgca ctggcgctga
       61 aaattaaaga acctcgcaat aaagaatcgt tgttctttat gtctgtcatg gaactgcgcg
      121 acctgctgat tgcgctggaa agtcgtatgc atcaaaagca taaactggat gctgctgcac
      181 gccttcagta tgagcaagct cgcgataaag tcattaagaa aatggcagaa aacatcccag
      241 aaattctggt tgatgagctt aaaaatgccg atattaatcg tcgggttaac acgctggaac
      301 ttaccgataa tcaaggcgaa aatcttacct tcgtattaac gctacatgac ggtagcaaat
      361 gtgagttagt cgtcaatgag ttgcagattg aaatgctggc gcgagcaatc attcatgcaa
      421 ttaataatgc ggaaatgcgt gaactggcat tacgtattac ctcactgtta gatttcctgc
      481 cgttatatga cgttgactgc caggaaaatg gcaatctgga atatgacacc tattcccaac
      541 cggaatggaa acataacctg ttcgaccatt atctggcggt gctttaccgc tttaaagatg
      601 aaagtggcaa agaacaattt agcggcgcag tggtgaaaac gcgtgaagca acgccgggta
      661 aagaaataga ggcgatcact cgccgaatgc ttgatttcag ccaacgactg aaaaaactcg
      721 cgggtgtgcc atgtcaggtc tatgttcgca ccgtagcggc gaataacgcc caaccgctaa
      781 cccaggatca atgcttacgc gcgctgcatc acttacgtgt tcaatccacc agcaaaactg
      841 caccacaggc gaaataatct catctttgct aatgcgaggc tggagccatc cagcctgaaa
      901 tgactgataa cgtgatcgtt ggtcatgccg gatgcggcgt aaacgcctta tccggcctac
      961 aaattctcaa gcattcaatc agttgcaatg cctgctgtag gcctgataag cgaagcgcat
     1021 caggcaataa tacgtttgtc acccagcctc tggatcacat cagttcgggc acttataaac
     1081 ctgaccgata atctggctat ccgtcgggac aaaactggac aacattccct gcgacgggct
     1141 actgatgcca taaatcacgt taccgcccat tgcagccgcc tggttgcgca gatcgtttgc
     1201 tgcgccgcgc atagaaccgc cctcttctcc gtgttgcccg gaaagccagt tgctttgctt
     1261 acctgtcgca gtaccaatca gctggcactc tgcgcctggc tgctcgtcca caatgcgtac
     1321 actctgaccg gcagcactca attcgttgct ggagctacaa cccgccatca gtagcgcggc
     1381 accgacaatc cctgctaagt attttacgtg catgttattc cccataatca atgagctgga
     1441 cgccactcgc gtcgtccgtg tctgaatctt atactagaaa gatgaccaaa agaaaaaccc
     1501 ccagacattt ctgcccgggg gtttgtttat ttctgcgagg tgcagggcaa ttacatcatg
     1561 ccgcccatgc cacccatgcc gcccataccg ccagcagcgc ctaagtcagc tgcatcattt
     1621 ttcggcaggt cggtaaccat gcactcggtg gtgatcatca ggccagccac agaagccgcg
     1681 tactgcagag cagaacgggt tactttggtt gggtccagga tacccatgtc gatcatgttg
     1741 ccgtattctt cggttgctgc gttgtaaccg tagttgccgt cgccgccttt aacggtgtta
     1801 gcaacaacag acggttcttc gccgcagttc aggacgatct gacgcagcgg agcttccatt
     1861 gcacgcagtg caactttgat acccacgttc tggtcttcgt tctgaccacg caggtcagcc
     1921 agtttagacg ctacgcggat cagcgcaaca ccaccaccag caaccacgcc ttcttctacc
     1981 gcagcacggg tcgcgtgcag ggcgtcttca acgcgtgctt ttttctcttt catttcaact
     2041 tcggtagcag cacctacttt gataactgca acgccgcctg ccagtttcgc tacgcgttcc
     2101 tgcagttttt cacggtcgta gtcagaagtt gcttcttcaa tctgctgacg gatctgagca
     2161 acacggccct ggattgcagc ttcttcaccc acgccatcga tgatagtggt ggtgtctttg
     2221 ttgatcacaa cacgtttagc ctgacccagg tcttccaggg ttgctttttc cagctccata
     2281 ccgatctctt cagagattac ggtaccgcca gtcagggttg cgatatcctg cagcatagct
     2341 ttacgacgat cgccgaagcc cggagcttta accgcagcaa ctttcacgat gccacgcatg
     2401 gtgttaacaa ccagagttgc cagcgcttcg ccttcaacat cttcagcgat gatcagcagc
     2461 ggtttgcctg ctttggcaac agcttccaga accggcagca tttcgcggat gttagagatt
     2521 ttcttgtcag ccagcaggat gaacgggctt tccagttcta ctgcgccagt ttccggcttg
     2581 ttgatgaagt aaggagacag gtagccacgg tcgaactgca taccttcaac cacgtccagt
     2641 tcgtcctgca gaccggtacc gtcttcaacg gtgataacgc cttctttacc gactttgtcc
     2701 atcgcttcag cgatcagttt acctacggtt tcgtcggagt tagcggagat ggtaccaacc
     2761 tgagcaatcg ctttagagtc agagcacggt acggacagcg ctttcagttc ttcaactgca
     2821 gcggtaacgg ctttgtcgat accacgtttc aggtccatcg ggttcatgcc cgcagcaaca
     2881 gctttcagac cctcagtgat gatagcctga gccagtacag ttgcagtggt ggtaccgtcg
     2941 cctgcagcgt cgttcgcttt agaggcaact tctttcacca tctgcgcacc catattttcg
     3001 aacttgtctt ccagttcgat ttcacgagca acggaaacac catctttggt gatggtcggt
     3061 gcaccgaaag atttatccag aactacgtta cggcctttcg gaccgagggt aactttcact
     3121 gcatctgcca gtacgtttac gccgcgcagc attttcacac gagcgtcgtt accgaatttt
     3181 acgtctttag ctgccattat ctttattcct taaattcgta tgttcagtgt cgtgcgagga
     3241 ttacgcttca acaattgcca gaatgtcgct ttcggacatg atcaacactt cttcattgtc
     3301 gatcttctca gatttcacac cgtagccatc gttgaaaata acgatgtcgc caactttcac
     3361 atccagcggc ttcacttcgc cattttcaag gatacggcca ttgccgacag ccagcacttc
     3421 gccgcgggtg gatttagccg ctgcagagcc ggtcagaacg atgccgccag cagatttagt
     3481 ttcaacttct ttacgcttga cgatcacgcg atcatgcaat ggacgaatat tcattgataa
     3541 ctctcctttg agaaagtccg tatctgttat gggtgacgcc ggagcttacg tggtttcccg
     3601 gctggtgacc agagaaatgg ggatgaggat tcgccccttc aagggggaaa aagaaaaaaa
     3661 attctgatca gcacaaaatc gggtgaaaac cctgattcac ctcacatttc atcgcaattt
     3721 cttcatcgcc gtcataagcg aatctgattg tgctaccatc gaaaatctac gcagttgccc
     3781 aaaatttggg cgcaatcgga tatcaaccca tgagtggact caaacaagaa ctggggctgg
     3841 cccagggcat tggcctgcta tcgacgtcat tattaggcac tggcgtgttt gccgttcctg
     3901 cgttagctgc gctggtagcg ggcaataaca gcctgtgggc gtggcccgtt ttgattatct
     3961 tagtgttccc gattgcgatt gtgtttgcga ttctgggtcg ccactatccc agcgcaggcg
     4021 gtgtcgcgca cttcgtcggt atggcgtttg gttcgcgact tgagcgagtc accggctggt
     4081 tgtttttatc ggtcattccc gtgggtttgc ctgccgcgct acaaattgcc gccgggttcg
     4141 gccaggcaat gtttggctgg catagctggc aactgttgtt ggcagaactc ggtacgctgg
     4201 cgctggtgtg gtatatcggt actcgcggtg ccagttccag tgctaatcta caaaccgtta
     4261 ttgccggact tatcgtcgcg ctgattgtcg ctatctggtg ggcgggcgat atcaaacctg
     4321 cgaatatccc cttcccggca cctggtaata tcgaacttac cgggttattt gctgcgttat
     4381 cagtgatgtt ctggtgtttt gtcggtctgg aagcatttgc ccatcttgcc tcggaattta
     4441 aaaatccaga gcgtgatttt cctcgcgcat tgatgattgg tctgctgctg gcaggattag
     4501 tctactgggg ctgtacggta gtcgtcttac acttcgacgc ctatggtgaa aaaatggcgg
     4561 cggcagcatc gcttccaaaa attgtagtgc agttgttcgg tgtaggagcg ttatggattg
     4621 cctgcgtgat tggctatctg gcctgctttg ccagtctcaa catttatata cagagcttcg
     4681 cccgcctggt ctggtcgcag gcgcaacata atcctgacca ctacctggca cgcctctctt
     4741 ctcgccatat cccgaataat gccctcaatg cggtgctcgg ctgctgtgtg gtgagcacgt
     4801 tggtgattca tgctttagag atcaatctgg acgctcttat tatttatgcc aatggcatct
     4861 ttattatgat ttatctgtta tgcatgctgg caggctgtaa attattgcaa ggacgttatc
     4921 gactactggc ggtggttggc gggctgttat gcgttctgtt actggcaatg gtcggctgga
     4981 aaagtctcta tgcgctgatc atgctggcgg ggttatggct gttgctgcca aaacgaaaaa
     5041 cgccggaaaa tggcataacc acataatccg gcgtttcgac attaatcctg gcgatcgtct
     5101 ttatgatcaa ggcggtcgcg ctcatcatcc tttcgctggt actcaccatc aaaagtatta
     5161 ccgccaccgg tcccggcgct aaaaccgccg cctggcatac gagaaaagcg caaatgcggc
     5221 atcaacttca ctgtcagatg cttttgcacc ggcggtaata aaagcagaag accgaggaag
     5281 tcggtgaaaa agcccggtaa taaaagcagc aaaccggcaa tgatcagcga aacactttta
     5341 atcatctccg ccgctgggtt ttcacccgcc gccatttttt gctgcatcag cacgaaattc
     5401 ttaaagccct ggttacgtac caatgacatc ccgataactg acgtgaatat aaccagcacg
     5461 agggtcagca atacccccaa tacatgggca acctgaataa agattgaaat ctcaatatag
     5521 acataaagga aaatggcaat aaaaggtaac cagcgcaaag gtttctcctg taatagcagc
     5581 cggtaaaacc cggctacctg aatgggttgc gaatcgcgtt cagcttatat tgtggtcatt
     5641 agcaaaattt caagatgttt gcgcaactat ttttggtagt aatcccaaag cggtgatcta
     5701 tttcacaaat taataattaa ggggtaaaaa ccgacactta aagtgatcca gattacggta
     5761 gaaatcctca agcagcatat gatctcgggt attcggtcga tgcaggggat aatcgtcggt
     5821 cgaaaaacat tcgaaaccac atatattctg tgtgtttaaa gcaaatcatt ggcagcttga
     5881 aaaagaaggt tcacatgtca aacaacattc gtatcgaaga agatctgttg ggtaccaggg
     5941 aagttccagc tgatgcctac tatggtgttc acactctgag agcgattgaa aacttctata
     6001 tcagcaacaa caaaatcagt gatattcctg aatttgttcg cggtatggta atggttaaaa
     6061 aagccgcagc tatggcaaac aaagagctgc aaaccattcc taaaagtgta gcgaatgcca
     6121 tcattgccgc atgtgatgaa gtcctgaaca acggaaaatg catggatcag ttcccggtag
     6181 acgtctacca gggcggcgca ggtacttccg taaacatgaa caccaacgaa gtgctggcca
     6241 atatcggtct ggaactgatg ggtcaccaga aaggtgaata tcagtacctg aacccgaacg
     6301 accatgttaa caaatgtcag tccactaacg acgcctaccc gaccggtttc cgtatcgcag
     6361 tttactcttc cctgattaag ctggtagatg cgattaacca actgcgtgaa ggctttgaac
     6421 gtaaagctgt cgaattccag gacatcctga aaatgggtcg tacccagctg caggacgcag
     6481 taccgatgac cctcggtcag gaattccgcg ctttcagcat cctgctgaaa gaagaagtga
     6541 aaaatatcca acgtaccgct gaactgctgc tggaagttaa ccttggcgca acagcaatcg
     6601 gtactggtct gaacacgccg aaagagtact ctccgctggc agtgaaaaaa ctggctgaag
     6661 tcactggctt cccatgcgta ccggctgaag acctgatcga agcgacctct gactgcggcg
     6721 cttatgttat ggttcacggc gcgctgaaac gcctggctgt gaagatgtcc aaaatctgta
     6781 acgacctgcg cttgctctct tctggtccac gtgccggcct gaacgagatc aacctgccgg
     6841 aactgcaggc gggctcttcc atcatgccag ctaaagtaaa cccggttgtt ccggaagtgg
     6901 ttaaccaggt atgcttcaaa gtcatcggta acgacaccac tgttaccatg gcagcagaag
     6961 caggtcagct gcagttgaac gttatggagc cggtcattgg ccaggccatg ttcgaatccg
     7021 ttcacattct gaccaacgct tgctacaacc tgctggaaaa atgcattaac ggcatcactg
     7081 ctaacaaaga agtgtgcgaa ggttacgttt acaactctat cggtatcgtt acttacctga
     7141 acccgttcat cggtcaccac aacggtgaca tcgtgggtaa aatctgtgcc gaaaccggta
     7201 agagtgtacg tgaagtcgtt ctggaacgcg gtctgttgac tgaagcggaa cttgacgata
     7261 ttttctccgt acagaatctg atgcacccgg cttacaaagc aaaacgctat actgatgaaa
     7321 gcgaacagta atcgtacagg gtagtacaaa taaagaaggc acgtcagatg acgtgccttt
     7381 tttcttgtga gcagtaactt aaaaataaca acctaatatc aacttgttaa aaaacaagga
     7441 aggctaatat gctagttgta gaactcatca tagttttgct ggcgatcttc ttgggcgcca
     7501 gattgggggg aataggtatt ggttttgcag gcggattggg ggtgctggtt cttgccgcta
     7561 ttggcgttaa acccggtaac atcccgttcg atgtcatttc cattatcatg gcggttatcg
     7621 ccgctatttc tgccatgcag gttgctggcg gtctggacta tctggttcat cagacagaaa
     7681 agctgctgcg ccgtaacccg aaatacatca cgatcctcgc accgatcgtg acctatttcc
     7741 tgactatctt tgctggtact ggcaacatat ctctggcgac actgccagtt atcgctgaag
     7801 ttgcgaagga acaaggcgtc aaaccttgcc gtccgctgtc tactgcagtg gtatccgcgc
     7861 agattgcgat caccgcatcg ccaatctcag cggcagtggt ttacatgtct tccgtgatgg
     7921 aaggtcatgg catcagctac ctccatctgc tctccgtggt catcccgtcc accctgctgg
     7981 cggttctggt gatgtccttt ctggtcacta tgctgttcaa ctccaaactc tctgacgatc
     8041 cgatttatcg caagcgtctg gaagagggcc tggttgaact gcgcggtgaa aagcagattg
     8101 aaatcaaatc cggtgcaaaa acgtccgtct ggctgttcct gctgggcgta gttggcgtgg
     8161 ttatctatgc aatcatcaac agcccaagca tgggtctggt tgaaaaaccg ctgatgaaca
     8221 ccaccaacgc aatcctgatc atcatgctca gcgttgcaac tctgaccacc gttatctgta
     8281 aagtcgatac cgacaacatc ctcaactcca gcaccttcaa agcaggtatg agcgcctgta
     8341 tttgtatcct gggtgttgcg tggctgggcg atactttcgt ttccaacaac atcgactgga
     8401 tcaaagatac cgctggtgaa gtgattcagg gtcatccgtg gctgctggcc gtcatcttct
     8461 tctttgcttc tgctctgctg tactctcagg ctgcaaccgc aaaagcactg atgccgatgg
     8521 ctctggcact gaacgtttca ccgctgaccg ctgttgcttc tttcgctgcg gtgtctggtc
     8581 tgttcattct gccgacctac ccgacgctgg ttgctgcggt acagatggat gacacgggta
     8641 caacccgtat cggtaaattc gtcttcaacc atccgttctt catcccgggt actctgggtg
     8701 ttgccctggc cgtttgcttc ggcttcgtgc tgggtagctt catgctgtaa tgaccaatcg
     8761 cggggcgttc aagccccgct ttctttcccg ccgactaaca tccttccccc gtccgttgta
     8821 tagtgacctc tctcttgcgg ttccatctgt tcttgcgagg tgtttatgct tgatgaaaaa
     8881 agttcgaata ccgcgtctgt cgtggtgcta tgtaccgcac cggatgaagc gacagcccag
     8941 gatttagccg ccaaagtgct ggcggaaaaa ctggcggcct gcgcgacctt gatccccggc
     9001 gctacctctc tctattactg ggaaggtaag ctggagcaag aatacgaagt gcagatgatt
     9061 ttaaaaacta ccgtatctca ccagcaggca ctgctggaat gcctgaagtc tcatcatcca
     9121 tatcaaaccc cggaacttct ggttttacct gttacacacg gagacacaga ttacctctca
     9181 tggctcaacg catctttacg ctgatcctgc tactttgcag cacttccgtt tttgccggat
     9241 tattcgacgc gccgggacgt tcacaatttg tccccgcgga tcaagccttt acttttgatt
     9301 ttcagcaaaa ccaacatgac cttaatctga cctggcagat caaagacggt tactacctct
     9361 accgtaaaca gatccgcatt acgccggaac acgcgaaaat tgccgacgtg cagctgccgc
     9421 aaggcgtctg gcatgaagat gagttttacg gcaaaagcga gatttaccgc gatcggctga
     9481 cgcttcccgt aaccatcaac caggcgagtg cgggagcgac gttaactgtc acctaccagg
     9541 gctgtgctga tgccggtttc tgttatccgc cagaaaccaa aaccgttccg ttaagcgaag
     9601 tggtcgccaa caacgcagcg tcacagcctg tgtctgtttc gcagcaagag cagcacaccg
     9661 cgcaattgcc cttttccgcg ctctgggcgt tgttgatcgg tattggtatc gcctttacgc
     9721 catgcgtgct gccaatgtac ccactgattt ctggcatcgt gctgggtggt aaacagcggc
     9781 tctccactgc cagagcattg ttgctgacct ttatttatgt gcaggggatg gcactgactt
     9841 acacggcgct gggtctggta gttgccgccg cagggttaca gttccaggcg gcgctacagc
     9901 acccatacgt gctcattggc ctcgccatcg tctttacctt gctggcgatg tcaatgtttg
     9961 gcttgtttac tctacaactc ccctcttcgc tgcaaacacg tctcacgttg atgagcaatc
    10021 gccaacaggg cggctcacct ggcggtgtgt ttgttatggg ggcgattgcc ggactgatct
    10081 gttcaccatg caccaccgca ccgcttagcg cgattctgct gtatatcgcc caaagcggga
    10141 acatgtggct gggcggcggc acgctttatc tctatgcgtt gggcatgggc ctgccgctga
    10201 tgctaattac cgtctttggt aaccgcttgc tgccgaaaag cggcccgtgg atggaacaag
    10261 tcaaaaccgc gtttggtttt gtgatcctcg cactgccggt cttcctgctg gagcgagtga
    10321 ttggtgatgt atggggatta cgcttgtggt cggcgctggg tgtcgcattc tttggctggg
    10381 cctttatcac cagcctacag gctaaacgcg gctggatgcg cgtggtgcaa ataatcctgc
    10441 tggcagcggc attggttagc gtgcgcccac ttcaggattg ggcatttggt gcgacgcata
    10501 ccgcgcaaac tcagacgcat ctcaacttta cacaaatcaa aacggtagat gagttaaatc
    10561 aggcgctcgt tgaagccaaa ggcaaaccgg tgatgttaga tctttatgcc gactggtgcg
    10621 tcgcctgtaa agagtttgag aaatacacct tcagcgaccc gcaggtgcaa aaagcgttag
    10681 cagacacggt cttacttcag gccaacgtca cggccaacga cgcacaagat gtggcgctgt
    10741 taaagcatct taatgtcctt ggcctaccga caattctctt ttttgacgga caaggccagg
    10801 agcatccaca agcacgcgtc acgggcttta tggatgctga aaccttcagc gcacatttgc
    10861 gcgatcgcca accgtgaacg acacttgcag tgggaaagac ggaggaaaat agcgtgcaac
    10921 gtgaagatgt actgggagaa gccctgaaat tattagaatt acaagggatt gccaacacca
    10981 cgctggagat ggttgctgaa cgtgtggatt atccactgga cgagctacgc cgcttctggc
    11041 cagacaaaga ggcaatcctc tacgatgcgc tgcgttatct tagccaacag atagatgtct
    11101 ggcgtcgtca gctgatgctg gacgaaacgc aaaccgccga acaaaagctg ctggcacgtt
    11161 atcaggcgtt atcggagtgc gttaaaaaca accgctatcc gggctgtcta tttatcgctg
    11221 cctgtacgtt ttatcccgat cctggccacc ctattcatca actggccgat cagcaaaaaa
    11281 gcgcggccta cgatttcacc cacgaactgt taaccacact ggaagttgac gatccggcga
    11341 tggtagcaaa gcagatggaa ctggtgctgg aaggctgttt aagccgaatg ctggtgaatc
    11401 gtagccaggc ggatgtcgac actgcacatc ggctggcgga agatatcctg cgcttcgccc
    11461 gctgccgcca gggtggtgca ttgacctgac agaaacacag aaaagaagcg atttgccgca
    11521 atcttaagca gttgaatcgc ttttactgaa attaggttga cgagatgtgc agattacggt
    11581 ttaatgcgcc ccgttgcccg gatagctcag tcggtagagc aggggattga aaatccccgt
    11641 gtccttggtt cgattccgag tccgggcacc aaattcatat caacggacct ccacggaggt
    11701 ccgtttttcg tttcagaacg ccacaattta agcgttctgc ctccaaatca attctaccga
    11761 actcaaccag attctcccca catcaacctc attgtgtggg tataattgcg ggtatacccc
    11821 agttcgacag aatttgtacc cgctttaacg cattcagaag gctgaactat ggcactgact
    11881 gacgcaaaaa tccgggctgc aaagcccact gacaaggctt ataaactcac tgacggggcc
    11941 ggcatgttcc tgctggttca tcctaatggt tcccgttact ggcgtctccg ttatcgtatt
    12001 ctgggtaagg agaaaaccct ggcacttggt gtgtatccgg aagtttctct ctccgaagct
    12061 cgtacaaaac gggatgaggc ccgaaaactg atttcagagg ggattgaccc ttgcgaacag
    12121 aaaagagtta aaaaagtagt ccctgattta cagctctctt ttgaacatat tgcacgacgc
    12181 tggcatgcca gtaataaaca atgggcacaa tcacacagcg ataaagtact caaaagcctc
    12241 gagacacacg ttttcccctt tatcggcaac cgggatatca caacactcaa taccccggac
    12301 ctgcttattc ctgttcgtgc tgcagaagca aaacaaattt atgaaatcgc cagtcgtctg
    12361 cagcaaagaa tatctgctgt aatgcgttat gccgtacagt ctggcatcat cagatataat
    12421 cctgctctgg atatggctgg cgcattgacc tctgtaaaac gacagcatcg ccccgctctt
    12481 gatctttcac gtctgcctga acttctgtcg cgtattaaca gttataaagg tcagcctgtc
    12541 acccggcttg ctgttatgct gaatttactg gtttttattc gctccagtga actcagatat
    12601 gcccgctggg ctgaaattga tattgacaat tcaatgtgga ctattccagc cgaacgcaaa
    12661 cctctgccag gggtaaaatt ctcacaccgg ggctccaaga tgcgaacacc acatcttgtg
    12721 ccactcagca aacaggctgt agccatactg acagaacttc agacatgggc tggtgaaaat
    12781 ggtctgatct ttacgggagc acatgacccg cgtaaaccaa tcagtgaaaa taccgtaaat
    12841 aaggccctca gagtgatggg gtatgacaca accaaggaag tctgtggcca tggattccgg
    12901 gcgatggcgt gcagtgcatt gattgaatcc ggcttatggt caagagatgc ggttgaacgt
    12961 cagatgagtc atcaggagcg caacggagta cgtgccgcgt atattcataa agcagaacat
    13021 ctggaagaac gtcggcttat gctgcaatgg tgggcagatt ttctggatgc aaacagggag
    13081 gagtgtatca gtccgtttga atatgcaaaa gttaacaatc cactgaaaag gtgactgaac
    13141 accatttaca cacatgctct tcctcttaag gggaagagca cccgcctcaa tcaatttctt
    13201 ttttatgccg gcggaaccat cagccaggct gaggttctca ttcaataact caacgtctta
    13261 ccacagaaca ggattcactg tattatcatg ggcaacgtta atcccggaca ataaaaggac
    13321 accgatgcca ggcatcacaa tttttatagc ctgcagatta tggtccatcc ttttttacag
    13381 gttcagaata tgactggcaa attacgcttt gaagtgaacg ataaccaggg ctgtttcata
    13441 tttccggaaa cctggtttgg ctcgttgctg gatgagtttg aagaactgat tgatgcatac
    13501 gatgcggatg aaatcagcga aacaagttac atcaacaaac tcaggcgcct tgcccgacag
    13561 gagaatgact ttattgatgt acacgctcac ttggcatacg tatttctgga gcagaatgcc
    13621 ccgcgtaagg cgctgaatgc tgcccttaaa gggctggcag ttggcaatcg tcttatccct
    13681 gaaggtttca gtggcagaat catctggata catcctgaca accgaccttt tcttcgtgcc
    13741 ctctatgcgg caatcctggc aaatgcacat ttacagcgtc atcaggatgc catcatgctc
    13801 attgaaaaaa tactggatta caatcccgaa gataatcatg gtgcacgctg gctactggga
    13861 ccggaactgt tacgcactgg cgctcatgaa caggcacgcc atatactgca ggaacatgca
    13921 gatgaatttt caccttactg gtatgaactc ggccttctgc attttcttaa tggggaactg
    13981 gtaaaagctg caactgcatt tcgtcgcggc tttgcggcaa atacttacat cgcagaaata
    14041 ctgtgcggaa atctgcatcc atttccactt gctgtatggc ataacttttc aggcggtccg
    14101 gatactgccg aagattatta tgccacatac cacccgttat gggggcaata tccggaagca
    14161 ttgctgtttg taaactggct ctataatcat tcctctgtgc tgcatgaacg ggcagaaatc
    14221 attaaatgcg ccgaaatgct gatgcaggaa gatgatttcg aaatatgcga aagtatttta
    14281 agacagcagg agaagttgcg tgaaagaatt gatgagacgc tttctgagaa aattgtacag
    14341 aaatgcagaa atatgaatgg tgaatatgtc tggccctgga tattgccgtt ttcagcggca
    14401 ggcatgaaac atactggcat acagtatcag tagatattgc attagtgtat cctgcacaca
    14461 agtaataatt tatccaccaa taataacact gttaatgtcc ccttcccctg gttgtcagcc
    14521 aggggttatc ttctgaatat ttcttttgaa aaggataaca caataaatta tttttatgaa
    14581 ttatcccatg gactcattaa caccctttca taatgcttta ttgtcaaaca cgttatggct
    14641 gacatcaaaa aaaaccggat ttcctctgcc agcggataat cacctccccg gtgttttcgg
    14701 ttggtctggt tactcctgtc tggttattag caagataatt gctataaaca gtggaaaact
    14761 catcgtacat aatctggtga tgaacattac gcttattttc ccttgaccgg aagaatcaga
    14821 ggctgcggtt tcagactgtc tgccggtaca ttcctctctc cgttaaaaac cataatgggt
    14881 tcattatctt cgtctgtcag tagattgaat ggcggtatat tttcagtacg aatgccggtc
    14941 agccactgaa aaatacctgc gaaatgacgg gcactgattt ttctgctgac ggactgatga
    15001 gacgtgatgt cactggcggt aataatcagg ggaacgctgt agcctccctg cacatgacca
    15061 tcatgatgaa caggattagc actgtcgctg accgacagcc catggtcaga aaagtaaagc
    15121 atgacgaaat gacgggaatg ccggcgaagg ataccatcaa gctgaccgag aaagttatcc
    15181 agtttactga tgctggcgag gtaacaggca acctttcggg gatactgctc caggtaatga
    15241 ttcggccagg agtgaagccg gtcacacggg ttcggatgag accccatcat gtgcaggaat
    15301 atcaccttcg gagaggattt atccgccagt gcacgttctg tttcctgtaa caacaacatg
    15361 tcatccgttt tacgggaagc aaagctgcct ttcttgagga aaacggtatg ctccgcatca
    15421 gaagcaataa cagagatgcg tgtatcatgc tcccccagct ttccctgatt ggatatccac
    15481 catgtgctgt atcctgcttt tgctgccagc gccaccacgt tgttgccgga atcagggttc
    15541 tgctcatagt cataaatcag tgtccggctc agggaaggca cagtactggc tgctgccgat
    15601 gtataaccgt caataaataa accgggagcc gtattcagcc acggtgtggt tggcacagga
    15661 tagccatata ccgacatata atccctgcgc acactctcac cagtgacgat aacaatcgtg
    15721 tcatacaacg gtacacccgg caggattttc cagttgtcag ccccgtgctg attcagttgt
    15781 ttataacgct gcatttcacg caatgtgtca gttgtcccca caacagttcc tttaaccatc
    15841 cgcaacggcc agctgtttac tgagcataat acgaacagca gcagtgccag ccagttacgg
    15901 tgaccgcggt ggtgtgttcg ccagaaaatc accatgaata ccagaatcgc ggcactgacc
    15961 agaaaatgat aaacaggaat catcccggta aactccgctg cctcatcagt tgtggtctgc
    16021 aacaacgcga caataaaact gttgttgatt ttaccgtacg tcataccggc aggcgcatac
    16081 agtgcacaac agaacagaaa taacagcgct gtaatggatg tgagggtatt tctgtgtgca
    16141 aggagcagaa ggagaaacag aagcagcaca tttcctgttg cattcttctc agtgtatccg
    16201 catgcaattg tggttattgc agaaacaaca aaaaagaata aaaacaataa aatccggggg
    16261 gtgttgcccg gacaaaacag ttttctgata ttcatcggag tatatcgaca acattattat
    16321 gaagagaaca agataataaa aatcagaaat tatctgtaaa acagataaaa gacaaccctg
    16381 cagtaataga ctgcagggta tttctgttta attgcagaag atatgcaatt atcttaatta
    16441 cagaatatac gcaattatcg ttcaggagca gtgtcgtcag aagttataag tcataccaag
    16501 catgatgtca tgacttttaa catcaacttc tgacttatat ttatcgcccc actcgtcctt
    16561 gtaactcaca ctgctgtcac ctgcatcaag atagcgatag ctgaggtcca gagcgatatc
    16621 cggggttacg tcatagcgga cacccgcgcc aaggctccat gcgaagttgt cagcagagcc
    16681 tgaacgtgac aacgattcgc gaccactgct tccgtactca taatcccagg tactgatacc
    16741 ggttgttttc tggtgaattc tggcgtagcc aatccctgcg gatacccatg gtgtgaatgc
    16801 gctgtcattc cggaagtcat agtacgcatt cagcattagt gtgttgactg acacctcatt
    16861 cttcaggtca tcacgccagt aaccacctga ccagctgtct ttatctacgt tatacttcga
    16921 atcagctttt ccacgagcgt aaaactccag ttctgtacga accggaatac tgaactgcgg
    16981 ataaaaatca taaccggccg caataccgcc actgaatacc gtatcatggt catcgccgcc
    17041 tttatacttt gatgtttctt cctcatctcc tgacaggaaa cgctggtctg aaagtgacac
    17101 cacagaggca ccggctttac cggtcagata aaaaccactt ttaccttcct ttgctcctgc
    17161 atttgctgca aatacacagg ctgcgaccac cactgaaaca acaaaaacct tatt
//
LOCUS       DAPGUL010000097        17151 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.099, whole genome shotgun sequence.
ACCESSION   DAPGUL010000097 DAPGUL010000000
VERSION     DAPGUL010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17151
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.099"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            146..748
                     /locus_tag="RHX21_003412"
     CDS             146..748
                     /locus_tag="RHX21_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDV1988557.1"
                     /translation="MLAFCRSSLKSKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNK
                     TLARLAQQHPVVVLFRHAERCDRSTNQCLSDKTGITVKGTQDARELGNAFSADIPDFD
                     LYSSNTVRTIQSATWFSAGKKLTVDKRLLQCGNEIYSAIKDLQSKAPDKNIVIFTHNH
                     CLTYIAKNKRDATFKPDYLDGLVMHVEKGKVYLDGEFVNH"
     gene            complement(787..1212)
                     /gene="nudI"
                     /locus_tag="RHX21_003413"
     CDS             complement(787..1212)
                     /gene="nudI"
                     /locus_tag="RHX21_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphatase NudI"
                     /protein_id="HDV1988558.1"
                     /translation="MRQRTIVCPLIQNDGAYLLCKMADDRGVFPGQWALSGGGVESGE
                     RIEEALRREIREELGEQLLLTEITPWTFSDDIRTKTYADGRKEEIYMIYLIFDCVSAN
                     REVKINEEFQDYAWVKPEDLVHYDLNVATRKTLRLKGLL"
     gene            1491..2033
                     /locus_tag="RHX21_003414"
     CDS             1491..2033
                     /locus_tag="RHX21_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311165.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988559.1"
                     /translation="MKKIALAGLAGMLLVSASVNAMSISGQAGKEYTNIGVGFGTEST
                     GLALSGNWTHNDDDGDVAGVGLGLNLPLGPLMATVGGKGVYTNPNYGDEGYAAAVGGG
                     LQWKIGNSFRLFGEYYYSPDSLSSGIQSYEEANAGARYTIMRPVSIEAGYRYLNLSGK
                     DGNRDNAVADGPYVGVNASF"
     gene            2133..3335
                     /locus_tag="RHX21_003415"
     CDS             2133..3335
                     /locus_tag="RHX21_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide deamidase-related
                     protein YfaY"
                     /protein_id="HDV1988560.1"
                     /translation="MLKVEMLSTGDEVLHGQIVDTNAAWLADFFFHQGLPLSRRNTVG
                     DNLDDLVTILRERSQHADVLIVNGGLGPTSDDLSALAAATAKGEGMVLHEAWLKEMER
                     YFHERGRVMAPSNRKQAELPASAEFINNPVGTACGFAVQLNRCLMFFTPGVPSEFKVM
                     VEHEILPRLRERFSLPQPPVCLRLTTFGRSESDLAQSLDTLQLPPGVTMGYRSSMPII
                     ELKLTGPASEQQAMEKLWLDVKRVAGQSVIFEGTEGLPAQISRELQNRQFSLTLSEQF
                     TGGLLALQLSRAGAPLLACEVVPSQEETLAQTAHWITERRANHFAGLALAVSGFENEH
                     LNFALATPDGTFALRVRFSTTRYSLAIRQEVCAMMALNMLRRWLNGQDIASEHGWIEV
                     VESMTLSV"
     gene            3390..3860
                     /locus_tag="RHX21_003416"
     CDS             3390..3860
                     /locus_tag="RHX21_003416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001342598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase"
                     /protein_id="HDV1988561.1"
                     /translation="MSNPPYGERGVGASVARAARWGRIENYMAQVNDSLCLLVQVESK
                     TALDNLDEILDVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIETSIRRIRAAGKAA
                     GFLAVAPDMAQQCLAWGANFVAVGVDTMLYSDALDQRLAMFKSGKNGPRIKGSY"
     gene            complement(3901..4803)
                     /locus_tag="RHX21_003417"
     CDS             complement(3901..4803)
                     /locus_tag="RHX21_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HDV1988562.1"
                     /translation="MTESTTSSPHDAVFKTFMFTPETAGDFLEIHLPEPLRKLCNLQT
                     LRLEPTSFIEKSLRAYYSDVLWSVETSDGDGYIYCVIEHQSSAEKNMAFRLMRYATAA
                     MQRHLDKGYDRVPLVVPLLFYHGETSPYPYSLNWLDEFDDPQLARQLYTEAFPLVDIT
                     IVPDDEIMQHRRIALLELIQKHIRDRDLIGMVDRITTLLVRGFTNDSQLQTLFNYLLQ
                     CGDTSRFTRFIEEIAERSPLQKERLMTIAERLRQEGHQIGWQEGMHEQAIKIALRMLE
                     QGIDRDQVLAATQLSEADLAANNH"
     gene            complement(4997..6187)
                     /gene="glpC"
                     /locus_tag="RHX21_003418"
     CDS             complement(4997..6187)
                     /gene="glpC"
                     /locus_tag="RHX21_003418"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic glycerol-3-phosphate dehydrogenase
                     subunit C"
                     /protein_id="HDV1988563.1"
                     /translation="MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLK
                     DGALYDEALKYCINCKRCEVACPSDVKIGDIIQRARAKYDTTRPSLRNFVLSHTDLMG
                     SVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSIAAQQAQYK
                     DQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQ
                     AITNVESIREAVGVKGIPVIATSSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWR
                     KLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRKIPGLELTVLDSQCCGIAG
                     TYGFKKENYPTSQAIGAPLFRQIEESGADLVITDCETCKWQIEMSTSLRCEHPITLLA
                     QALA"
     gene            complement(6184..7443)
                     /gene="glpB"
                     /locus_tag="RHX21_003419"
     CDS             complement(6184..7443)
                     /gene="glpB"
                     /locus_tag="RHX21_003419"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase subunit GlpB"
                     /protein_id="HDV1988564.1"
                     /translation="MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGS
                     LDLLSHLPDGQPVTDIHSGLESLRQQAPAHPYSLLEPQRVLDLACQAQALIAESGAQL
                     QGSVELAHQRVTPLGTLRATWLSSPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLR
                     ELDLSVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMI
                     LMPACFGLADDKLWRWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPG
                     DEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERNGIREPILGLD
                     VLQTATRGEWYKGDFFAPQPWQQFGVTTDETLRPSQAGQTIENLFAIGSVLGGFDPIA
                     QGCGGGVCAVSALHAAQQIAQRAGGQQ"
     gene            complement(7433..9061)
                     /gene="glpA"
                     /locus_tag="RHX21_003420"
     CDS             complement(7433..9061)
                     /gene="glpA"
                     /locus_tag="RHX21_003420"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic glycerol-3-phosphate dehydrogenase
                     subunit A"
                     /protein_id="HDV1988565.1"
                     /translation="MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIAT
                     GATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTNGLFITLPEDDLS
                     FQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLD
                     AKEHGAVILTAHEVTGLIREGATVCGVRVRNHLTGETQALHAPVVVNAAGIWGQHIAE
                     YADLRIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYN
                     EIDDNRVTAEEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIV
                     LLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCTTADLALPGSQEP
                     AEVTLRKVISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVEN
                     LNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTSAQSIEQLSTFLNERWKG
                     VQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL"
     gene            9334..10692
                     /gene="glpT"
                     /locus_tag="RHX21_003421"
     CDS             9334..10692
                     /gene="glpT"
                     /locus_tag="RHX21_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate transporter"
                     /protein_id="HDV1988566.1"
                     /translation="MLSIFKPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLV
                     RKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSKFIMGSVSDRSNPRVFLPAGLIL
                     AAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSV
                     WNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLP
                     PIEEYKNDYPDDYNEKAEQELTAKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWS
                     PTYLKEVKHFALDKSSWAYFLYEYAGIPGTLLCGWMSDKVFRGNRGATGVFFMTLVTI
                     ATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFG
                     YLGGSVAASAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHEQLLQKRN
                     GG"
     gene            10697..11773
                     /gene="glpQ"
                     /locus_tag="RHX21_003422"
     CDS             10697..11773
                     /gene="glpQ"
                     /locus_tag="RHX21_003422"
                     /EC_number="3.1.4.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDV1988567.1"
                     /translation="MKLTLKNLSMAIMMSTIVMGSSAMAADSNEKIVIAHRGASGYLP
                     EHTLPAKAMAYAQGADYLEQDLVMTKDDHLVVLHDHYLDRVTDVADRFPDRARKDGRY
                     YAIDFTLDEIKSLKFTEGFDIENGKKVQTYPGRFPMGKSDFRVHTFEEEIEFVQGLNH
                     STGKNIGIYPEIKAPWFHHQEGKDIAAKTLEVLKKYGYTGKDDKVYLQCFDADELKRI
                     KNELEPKMGMDLNLVQLIAYTDWNETQQKQPDGSWVNYNYDWMFKPGAMKQVAEYADG
                     IGPDYHMLIEETSQPGNIKLTGMVQDAQQNKLVVHPYTVRSDKLPEYTTDVNQLYDAL
                     YNKAGVNGLFTDFPDKAVKFLNKE"
     gene            complement(11815..12057)
                     /locus_tag="RHX21_003423"
                     /pseudo
     CDS             complement(11815..12057)
                     /locus_tag="RHX21_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311149.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
     gene            12236..12886
                     /gene="inaA"
                     /locus_tag="RHX21_003424"
     CDS             12236..12886
                     /gene="inaA"
                     /locus_tag="RHX21_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide kinase InaA"
                     /protein_id="HDV1988568.1"
                     /translation="MAVSAKYDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKL
                     YVKRMTHHLFHSVRYPFGRPTIVREVAVIKELERAGVIVPKIVFGEAVKIEGEWRALL
                     VTEDMAGFISIADWYAQHAVSPYSDEVRQAMLKAVALAFKKMHSINRQHGCCYVRHIY
                     VKTEGNAEAGFLDLEKSRRRLRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM"
     gene            complement(12940..13194)
                     /gene="yfaE"
                     /locus_tag="RHX21_003425"
     CDS             complement(12940..13194)
                     /gene="yfaE"
                     /locus_tag="RHX21_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like diferric-tyrosyl radical
                     cofactor maintenance protein YfaE"
                     /protein_id="HDV1988569.1"
                     /translation="MARVTLRITGTQLLCQDEHPSLLAALESHNVAVEYQCREGYCGS
                     CRTRLVAGQVDWIAEPLAFIQPGEILPCCCRAKGDIEIEM"
     gene            complement(13194..14324)
                     /gene="nrdB"
                     /locus_tag="RHX21_003426"
     CDS             complement(13194..14324)
                     /gene="nrdB"
                     /locus_tag="RHX21_003426"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006683700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="HDV1988570.1"
                     /translation="MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQ
                     LSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISI
                     PELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDE
                     LIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFA
                     FAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDL
                     FVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIP
                     WINTWLVSDNVQVAPQEVEVSSYLVGQIDAEVDTDDLSNFQL"
     gene            complement(14413..16698)
                     /gene="nrdA"
                     /locus_tag="RHX21_003427"
     CDS             complement(14413..16698)
                     /gene="nrdA"
                     /locus_tag="RHX21_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="HDV1988571.1"
                     /translation="MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELR
                     SHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPAL
                     YDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNR
                     VTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTP
                     TRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHT
                     GCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMD
                     YGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQR
                     VKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLN
                     DVNDENGEIALCTLSAFNLGAINSLDELEELAILAVRALDALLDYQDYPIPAAKRGAM
                     GRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACP
                     WFNETTYAKGILPIDTYKKDLDAIANEPLHYDWEALRESIKTHGLRNSTLSALMPSET
                     SSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLV
                     GIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAED
                     AQDDLVPSIQDDGCESGACKI"
BASE COUNT         4051 a         4183 c         4585 g         4332 t
ORIGIN      
        1 ttaggctttg catttggcaa aattttgagg cattttgccg acatcgtagg atttttaata
       61 ttacaccaac tgctaattat cgccagaaat gtcgctcaat tttacggtaa ttgtctggtt
      121 gcgcttgtct ataggtggag tttacgtgtt agctttttgc cgctcatcat tgaagtcaaa
      181 aaaatatttc atcattttac tggcgctcgc tgcaattgcc ggactgggta ctcatgccgc
      241 ctggagtagc aatggtttgc cacgtatcga caataaaaca ttggccagac tggcacagca
      301 gcacccggtt gtcgttttgt ttcgccatgc tgaacgttgc gatcgttcaa ccaatcaatg
      361 cttgtcagat aaaacaggta ttacggttaa aggtacccag gatgcccgtg aactgggcaa
      421 cgcttttagc gctgacatcc ctgatttcga tctttattcc agtaataccg tccggaccat
      481 tcagtcggcg acctggtttt ccgcgggtaa aaagctgacg gtagataaac gacttcttca
      541 gtgcggtaat gagatttata gtgcaattaa ggacttacaa agcaaagcgc ctgataaaaa
      601 tatcgttatt ttcacccata atcattgcct gacatatatt gctaaaaata agcgtgatgc
      661 gacatttaaa cctgattatc tggatggttt agtcatgcat gtggaaaaag gcaaagttta
      721 tctggatggg gaattcgtta accactaaat tttcaatctg acagccagtg atggctgtca
      781 tcattgttaa agaagacctt tcaaacgtaa cgtttttcgg gtggcaacat ttaaatcata
      841 atgcaccaga tcttcaggtt ttacccacgc gtagtcctga aactcttcgt ttattttcac
      901 ttctcggttg gcagaaacgc agtcaaaaat caggtaaatc atataaatct cttccttgcg
      961 accatctgca tacgtcttgg tgcgaatatc atcgctgaag gtccacggcg tgatttctgt
     1021 caaaagcagc tgttctccca gttcttcgcg aatttcgcgg cgtagtgcct cttcaattcg
     1081 ttcgccagac tccacgccgc cacccgaaag cgcccattga ccggggaaaa cgccgcgatc
     1141 gtcggccatt ttacacagca aataagcacc atcattttga atcaaagggc atacaatagt
     1201 ccgttgtcgc ataggggtat tccttataaa taaaaagaaa ccatgagaat acggtaactc
     1261 agaaatatgt gaaagtgaca gtaatctctt ttgcaatgat aactgcactt attattattt
     1321 ttgtgtgtat cggtaaagtg tgtttatttt ttcggcgttt aattatttaa gaagtattta
     1381 gttacaataa gtgactagat cccttttttc gctcattgaa tcctctgtgc caggcagtac
     1441 aatcccgcag ctttgggaat tttgattaat tgcttgtggg aaaggggata atgaaaaaaa
     1501 ttgcgctagc aggtctggcc ggaatgctgt tggtttctgc atcggtcaat gcaatgagca
     1561 tcagcggcca ggcgggtaaa gaatacacca atattggtgt cggttttggg actgaatcga
     1621 cgggcctggc tttaagcggt aactggacac ataacgacga cgacggtgac gtcgcgggcg
     1681 tggggctggg gttgaatctg cctctcgggc cgttaatggc gaccgttggc ggaaaaggcg
     1741 tttacaccaa cccgaattac ggcgatgaag gttatgccgc agcggtagga ggtggtttgc
     1801 agtggaaaat tggcaacagc ttccgtttgt ttggcgagta ttactactct ccggattcgc
     1861 tctccagcgg tattcaaagt tatgaggaag cgaatgctgg cgctcgttac accattatgc
     1921 gtccagtcag tattgaggcg ggttatcgct acctgaatct gtcgggtaaa gacggtaacc
     1981 gcgacaacgc cgtggctgac ggcccgtatg ttggggttaa cgccagtttc tgatcccttc
     2041 cggcgcggca ttctgtcgcg ccattcagtt tcttactacg ccttatctcc ctttgcgtta
     2101 tagtgattcg ataacaaaag caggagataa ccatgttaaa agtggaaatg ctatccaccg
     2161 gggatgaagt gttacacggg caaatcgttg acactaacgc tgcctggctg gccgattttt
     2221 tctttcatca ggggctgcca ttatctcgcc gcaatacggt gggggataac cttgatgact
     2281 tagtcaccat tcttcgcgaa cgtagtcagc acgccgatgt gctgatcgtt aacggcgggc
     2341 tgggaccgac cagcgatgat ttaagcgcac tcgccgctgc gacagcaaaa ggtgaaggca
     2401 tggtgctgca tgaagcctgg ctcaaagaga tggaacgcta tttccacgaa cgtggacgag
     2461 taatggcacc gagcaaccgt aaacaagcgg agctgcctgc cagtgctgaa tttatcaata
     2521 acccggtagg caccgcctgt ggttttgccg tgcagcttaa tcgttgcctg atgttcttta
     2581 ctcccggcgt accgtcagaa tttaaggtga tggtcgagca cgaaatcctg ccgcgtctgc
     2641 gcgagcgttt ttctttacca cagccgccgg tttgtctgcg tttaactacc tttggtcgtt
     2701 cggaaagcga tctggcacaa agcctggaca ctctacaact gccgccgggc gtaacaatgg
     2761 gctatcgctc ttcaatgccg attatcgaac tgaaactcac cggaccggca agcgagcaac
     2821 aggcgatgga aaaactgtgg ctggacgtta aacgtgttgc cggacagagc gtgattttcg
     2881 aaggcaccga aggactgccc gcgcagatca gtcgcgaatt gcaaaaccgc cagttcagcc
     2941 tgacgttgag cgagcaattc accggcggtt tattggcttt gcaactttct cgcgcaggtg
     3001 ctccattgct ggcgtgtgaa gtggttcctt cacaggaaga aaccctggcg caaactgcgc
     3061 actggattac agaacggcgg gccaaccatt ttgccgggct ggcactggct gtttcgggtt
     3121 tcgagaacga gcatctcaac tttgcgctag ccacgccaga cggcactttc gctctgcgtg
     3181 tgcgtttcag cactacacgc tacagcctgg ctatccgtca ggaagtgtgc gcaatgatgg
     3241 cactgaatat gctgcgccgt tggttaaacg gccaggacat cgccagtgag catggctgga
     3301 ttgaggttgt tgagtccatg accttatctg tctgattccg ccactctgtg ccggtttact
     3361 gcaccggcac attccccctc cggcaaaact tgtccaaccc tccctacggt gagcgtggtg
     3421 ttggggccag tgtggcacgg gctgcgcgct ggggacgcat tgagaattac atggcgcaag
     3481 ttaacgattc actttgtctg ttggtgcagg tggaaagtaa aacggcactg gataacctgg
     3541 acgagatcct cgacgtcgaa gggattgatg gcgtgtttat tggaccagcg gatctttctg
     3601 cgtcgttggg ctacccggat aacgccgggc acccggaagt gcagcgaatt attgaaacca
     3661 gcattcggcg gatccgtgct gcgggtaaag cggctggttt tctggctgtg gctcctgata
     3721 tggcgcagca atgcctggcg tggggagcga actttgtcgc tgttggcgtt gacacgatgc
     3781 tctacagcga tgccctggat caacgactgg cgatgtttaa atcaggcaaa aatgggccac
     3841 gcataaaagg tagttattga tatcaaaggc ccatggggat cggctgtggg cctgtgttaa
     3901 ttagtggtta ttcgctgcca gatcggcttc gcttagctgg gtggccgcga gcacctggtc
     3961 acgatcaatg ccctgttcca gcatgcgcaa agcaatttta atggcttgtt catgcatacc
     4021 ttcctgccag ccaatttgat gcccttcctg ccgtagccgt tcagcaatag tcattaatct
     4081 ctccttttgt agtggtgaac gttcggcaat ctcctcaata aaacgggtga aacgggaggt
     4141 atcgccgcat tgcagcagat aattaaacag tgtttgtagc tggctgtcat tagtgaagcc
     4201 tctaaccaaa agcgtggtga tcctgtcgac catgccgatt aaatcgcggt cgcgaatatg
     4261 cttttgaatc agttccagca gagctatacg ccgatgttgc atgatctcat cgtcaggtac
     4321 gatggtgata tccaccaacg gaaaagcttc ggtgtacaac tgccgggcaa gttgcggatc
     4381 gtcaaactca tccagccagt taagtgagta cgggtagggc gatgtttcgc catgataaaa
     4441 cagcaatggc accaccagcg gaactctgtc atagccttta tccaggtgac gctgcatggc
     4501 ggcagtggca tagcgcatta gccgaaaagc catattcttt tctgcagagc tttgatgttc
     4561 aatcacgcag tagatatagc cgtcaccgtc gctggtttcc acggaccaca aaacatccga
     4621 gtagtaagcg cgtaaacttt tttcaataaa actagtgggt tccaggcgta aggtttgcag
     4681 gttgcaaagc ttgcgcagtg gttctggtaa atgtatttcg agaaaatccc ctgcggtttc
     4741 gggtgtgaac ataaaggttt taaacaccgc atcatgcggg gaggatgttg ttgattcggt
     4801 catggttgtc cgtcacctga tatttatgat gacgcgacat tacgtctatc ccgggccttt
     4861 gacatctgtc agtttcagcc tttgcgagac attttcagag gaattttcaa agcgttgcaa
     4921 cgcatacatg gtgcgtggaa tcgcgctcgc aaaaatgccc gataagcaat gtgcttaccg
     4981 ggcatcaaaa ggtcggttaa gccagcgcct gggccagtag cgtaatcgga tgttcgcagc
     5041 gaaggctcgt ggacatctca atctgccatt tgcaggtttc gcagtcggtg atgaccagat
     5101 ccgcgccgct ctcttctatc tggcggaaca gtggcgcacc gatggcttgt gaggtggggt
     5161 agttctcttt tttgaaaccg taagtacccg caataccgca gcactgggaa tccagcaccg
     5221 ttaactcaag ccccgggatt ttacgcaaca gctccagggt gtagagcgtc cagcccattt
     5281 tttccatatg gcacggagtg tgataaacca ctttcagcgg cagcggtttc agcggtaacg
     5341 ttttgccttc gtccagcttg cgccacagcc agcgggttgc cagttcgata tgatcgcgca
     5401 agcctttgtt gtcgacattc agcacttccg ggtattcgtc gcgcagggca aatgtacagg
     5461 ttgaggaggt ggcaatcacc ggaatgcctt ttactcccac agcttcgcgg atcgactcta
     5521 cattcgtaat tgcctgtttg cgtgctttat cggtaaagcc gttggcgatt agcggtacgc
     5581 cgcagcattt ttctttgctg agcagttgta caccggtacc cattgcgttg agcactttaa
     5641 ttaaatcttt acctaactgc ggatggttgt agttaacgaa gcagccgtga aagaaagcga
     5701 cctggtcttt atattgtgct tgctgagccg ctatgctgcg ataccagcga cggaacgtgc
     5761 cgaaggagta tttcggtagc gtgcggcgat gatcgatttt taacgccgca tcaagcagct
     5821 gccgcaccgg tttcagcgag gtagcggtgt tgacgattgg tgcgaacggc gtggaaacgc
     5881 tacccatcag gtcggtatga ctcaacacaa aattacgcag cgacgggcgc gtggtgtcat
     5941 attttgcccg cgcgcgctgg ataatatcgc caatcttcac atcggacggg caggcgactt
     6001 cacaacgttt gcagttgatg caatatttca gcgcctcgtc atacagtgcg ccatctttca
     6061 aacgcagacg ctcgccatcc ggcccggctt gttttggccc tggataaccg ggattcaccc
     6121 ggctcaccgg gcaggcggtg gtgcagacgg tgcacttaat gcagttttcg aagctggtgt
     6181 cgttcattgt tggcctcctg cgcgttgggc aatctgttga gcggcatgta aagcactgac
     6241 ggcacaaaca ccgccgccgc atccctgggc gatgggatca aatccgccca gcaccgaacc
     6301 gatggcaaac aggttctcaa tggtttgccc tgcctgcgac gggcgtagcg tctcatcagt
     6361 ggttacaccg aactgctgcc acggttgcgg cgcaaaaaaa tcgcccttat accattcacc
     6421 ccgcgtggcg gtttgtagca catcaaggcc gagaatcggc tcgcgaatgc cgttacgttc
     6481 cgctaccagt ccgccactaa agaaactgcc gctggcgaga accgcgaaac gtggacgtag
     6541 cggaatatcg gcgtgattgc gggtccagat ttcattcact acgccatttt tacaggtcac
     6601 ttttttcact tcatcgcccg gcatccacac gccaccctgg cgcacaaact ggcgctgtaa
     6661 ctggttttgc agacgaatgc ccagcacgga aggcggcagc gttggcaaaa gcatcagtga
     6721 acaaggtagt ttttcattca accaacgcca cagtttgtca tcggccaggc cgaagcaggc
     6781 gggcatcagg atcatttcgc aggtattggc gacaggaata agcgcatcaa gtaacagcgg
     6841 ccagttttct tcattatcaa ggaaacgggc gatattcaca gcgcgaaatt cggtggcgtt
     6901 attgcgcagg acatccagtt ccggcagctc tatttctgcg gtttcaaccg aaagatccag
     6961 ttcgcgcaac gaagccgccg caagatgcgc ctggaaatcc atcagcccgc ttatccccac
     7021 tacacatatc ttcttcgcgg gtagcggcca gacgggaact tctggcgaac ttaaccaggt
     7081 tgcacgcaaa gtgccgagcg gggtaacgcg ctgatgggcc agttccacgc tgccctgcaa
     7141 ttgcgcaccg ctttcagcga tcaatgcctg cgcctggcaa gcgagatcga gcacgcgttg
     7201 tggttcgaga agactgtaag gatgggctgg tgcctgctga cgcaaagatt ccagtccact
     7261 gtgaatgtct gtcaccggtt gaccatcagg cagatggctc agcaaatcca gcgaaccgga
     7321 tgagaaatgc agcgcgcttt gaccacgcgt gacaatggca cagcgcaggc cgtgtttttg
     7381 cagttgcagg ccacagagta atccggcgag gccgccgccc ataatgacag tatcaaagcg
     7441 catctttctg ctccttctcc agaccacaca gtccctgata aacccagcgg gtaaattcgc
     7501 tttcgcgcag tgcgtctccc caggcgatgg gttgcacgcc tttccagcgt tcgttaagga
     7561 aggtggaaag ttgctcgata gattgcgcgg acgtcgtgac gttaaaacgt tgcagcagtc
     7621 cggcagcgcg gcaggcgcag agttcgccct ggcaggtacc catccccaca cgggtacgac
     7681 ggcgtaaatc cagcaggcta ttaacgttta aattttctac cgcgtactga acttcacccg
     7741 cagttaccgc ttcgcactca cataccaggc tacgatgcag acggccttcg ctcagccagg
     7801 caggcgtgcg atcgccatga cgataaaccg cagaaccgcg cagcggggca ggcagggaga
     7861 tgactttacg caaggtaact tcagcgggtt cttgtgaacc aggcagtgcc agatcggcag
     7921 tcgtacaggg gcgcgtgttg cccagtttgc ggcataccgc gtcggtagcc cattcagcca
     7981 tcagccgata ggtcatcagt ttgccaccgg tgatggtgat aaatccgtcc agaccatcgc
     8041 gttcagcatg gtcgagcagc acgatgccac ggctgacgtt acgtccgctc gggtcgtcat
     8101 cgctggcaac cagcgggcgc acgccagaat aggcccgcaa aatgcgcgtt ttcgccatca
     8161 cgggggccag tttttcccct tcacgcagca gaatatcaac ctcttctgcc gtcactcgat
     8221 tatcgtcaat ctcgttgtaa tcaatacgta aagaggtggt accaatcagc gaaatggtat
     8281 cgccaggcac cagaatatcg gcgtcggaag gtttacggca gcggttgatc acatgctggt
     8341 taatgcggtg atccatgatc agcagcgatc ctttcgccgg gaacatgcga atgcgcagat
     8401 cggcatattc ggcaatgtgt tgcccccaga tcccagcggc attaaccacg acaggtgcat
     8461 gaagggcctg agtttcgccg gtgagatgat tacgtacacg aacaccgcac accgtcgcgc
     8521 cttcacgaat cagccccgtg acttcatgag cggtaaggat aacggcaccg tgttctttgg
     8581 catccagcat gtttgctgcg gtcagacgaa atggatcaac ggtgccatcc ggaactttca
     8641 ccgcgccaat cagtgccggg ttaacggcag gttcgataat gcgcgcttgc tgcgggtcta
     8701 tagcttctgc gctgatccct gcttcttcgc aggcgcgaat aaaagtggcc tggaatgaga
     8761 ggtcatcttc cggcagggtg ataaacaggc cgttggttgg ttcaacgcag tgacgtgcaa
     8821 tgcgtttcag gatctggttt tcactaatgc attcgcgggc cgattccgca tcggttaccg
     8881 catagcgcgc accgctgtgc agcaggccgt ggttacgccc ggtggcaccg gttgcgatgt
     8941 cgtggcgctc aaccaaaatc acgcgcagcc cgcgcagggc acagtcgcgg gcaatcccgg
     9001 ctcccgttgc gccgccacca atgataatca cgtcacttga ttgcgagtcg cgagttttca
     9061 ttgttatccc tctgaagttc gttttttacc atttagccat agtaaaaaca tgaattgttt
     9121 gatttcgcgc atattcgctc ataattcgaa agtgaaacgt gatttcatgc gtcattctga
     9181 acattttgta aatcttattt aataatgtgt gcggcaattc acatttaatt tctgaatgtt
     9241 ttcttaacat cgcggcaact aaagaaacgg caggttctcc cactgaatca gtctgttaat
     9301 cataaataag accacgggcc acggaggctt tcaatgttga gtatttttaa accagcgcca
     9361 cacaaagcgc gcttacctgc tgcggagatc gatccgactt atcgtcgatt gcgctggcaa
     9421 attttcctgg ggatattctt tggctatgcg gcttactatt tggttcgtaa gaactttgcg
     9481 cttgctatgc cttatctggt tgagcaggga ttctcacgcg gtgatttagg ttttgccctt
     9541 tcggggatct cgattgctta tggattttcg aaattcatca tgggttcggt atcggatcgc
     9601 tcgaatccgc gcgttttcct gcccgcaggt ttgattctgg cggcggcagt gatgttgttt
     9661 atgggctttg tgccatgggc gacgtcgagc attgcggtga tgtttgtact gttgttcctc
     9721 tgcggttggt tccaggggat ggggtggccg ccgtgtggtc gtactatggt gcactggtgg
     9781 tcgcagaaag aacgtggcgg cattgtgtca gtgtggaact gtgcgcacaa cgtcggtggt
     9841 ggtattccgc cgctgctgtt cctgctgggg atggcctggt tcaatgactg gcatgcggcg
     9901 ctctatatgc ctgctttctg cgccattctg gtggcattat tcgcctttgc gatgatgcgc
     9961 gataccccgc aatcctgtgg cttgccgccg atcgaagagt acaaaaatga ttatccggac
    10021 gactataacg aaaaagcgga acaggagctg acggcgaagc aaatcttcat gcagtacgta
    10081 ctgccgaaca aactgctgtg gtatatcgcc atcgccaacg tgttcgttta tctgctgcgt
    10141 tacggcatcc tcgactggtc accgacttat ctgaaagagg ttaagcattt cgcgctggat
    10201 aaatcctcct gggcctactt cctttatgaa tatgcaggta ttccgggcac tctgctgtgc
    10261 ggctggatgt cggataaagt cttccgtggc aaccgtgggg caaccggcgt tttctttatg
    10321 acactggtga ccatcgcgac tatcgtttac tggatgaacc cggcaggtaa cccaaccgtc
    10381 gatatgattt gtatgattgt tatcggcttc ctgatctacg gtcctgtgat gctgatcggt
    10441 ctgcatgcgc tggaactggc accgaaaaaa gcggcaggta cggcagcggg ctttaccggg
    10501 ctgtttggtt acctgggcgg ttcggtggcg gcgagcgcga ttgttggcta caccgtggac
    10561 ttcttcggct gggatggcgg ctttatggta atgattggcg gcagcattct ggcggttatc
    10621 ttgttgattg ttgtgatgat tggcgaaaaa cgtcgccatg aacaattact gcaaaaacgc
    10681 aacggaggct aatggcatga aattgacgct gaaaaacctt agcatggcga tcatgatgag
    10741 cactatagtc atgggaagca gtgcaatggc ggcggacagc aacgaaaaaa tagtcatcgc
    10801 ccatcgcggt gccagtggat atttgccgga gcatacgctg ccagcaaaag cgatggcgta
    10861 tgcgcaggga gcggattatc tggaacagga tttggtgatg accaaagacg accatctggt
    10921 tgttctgcat gaccattatc tcgatcgtgt tactgatgtt gccgatcgtt tcccggatcg
    10981 ggcgcgcaaa gacggtcgtt actacgcgat agatttcacg ctggatgaaa ttaagtcgct
    11041 gaaatttacc gaaggtttcg atattgaaaa cggtaaaaaa gtgcagactt atccggggcg
    11101 tttcccaatg ggtaagtccg acttccgggt gcacaccttt gaagaagaga ttgaatttgt
    11161 tcaggggtta aatcactcta ccgggaaaaa tatcggtatt tatcctgaaa tcaaagcgcc
    11221 gtggttccat catcaggaag ggaaggatat tgcggcaaaa acgctggaag tgctgaagaa
    11281 atatggttac accggtaagg acgacaaagt ttatttgcaa tgttttgatg ctgatgagct
    11341 gaagcgtatt aagaatgagc tggaacctaa aatgggcatg gatctcaatc tggtacagtt
    11401 gattgcctat accgactgga atgaaacgca gcagaaacag ccggatggaa gctgggttaa
    11461 ttacaactac gactggatgt ttaagccggg tgctatgaaa caggtggcgg aatatgccga
    11521 cggtatcggg ccggattacc atatgttgat tgaggaaaca tcgcagccgg gtaatatcaa
    11581 actcactggc atggtgcaag atgctcagca gaataaactg gtagtgcatc cttataccgt
    11641 gcggtcagat aaactgcctg aatacactac tgatgtgaat cagttatatg atgctctgta
    11701 taacaaagcg ggtgtaaatg ggctgtttac tgatttccct gataaggcag taaaattcct
    11761 taataaagag taatgctact gcaggatggc gttcatgcgc catcctgtct cacatcaaat
    11821 ttttccattt accacgagtt gttccgtaca cgtttgtagt aaaaacagtg gactgccttc
    11881 taccggcttt tctttagcca gcaacgaaat ctgtcgatag aaagttggtt cgagaggaac
    11941 ggaacacaat tcacctgcaa tgcttttcag cgttaactct ggttgtaagg cgatgcctaa
    12001 tccctgtcga ataaaattca tcgctgtatc cgcctgatta aattcacatt ttatctgctg
    12061 ggcgcactat tagtggtagt ggctggtgga atctatgcgc tgcaaatgaa gggtaaaagc
    12121 ggtgtcaagc tagtagtggc aaaagaaatt cattaatacg acacgtttca ttaagatttt
    12181 cctcaggtaa ccacctatag tcattgtcgt taataaaaat aacaggcgat agggtatggc
    12241 agtttcagca aagtacgacg aatttaatca ctggtgggca acagagggcg actgggttga
    12301 agagcctaac tatcgccgta atggtatgag cggggtgcaa tgcgtcgagc gcaacggcaa
    12361 aaagctgtat gtaaagcgca tgacgcatca tctgtttcat tccgtacgtt atccgttcgg
    12421 ccgaccaacg attgtccgtg aggttgcggt aattaaagaa ctggaacggg ccggtgtcat
    12481 cgtgccgaag atcgtttttg gtgaagcggt gaaaattgag ggtgaatggc gagcgttgct
    12541 ggtgactgaa gatatggcgg ggttcatcag cattgctgac tggtatgccc agcatgcagt
    12601 atcgccttat tctgacgaag tacggcaagc catgttgaaa gcagtggcgc tggcgtttaa
    12661 gaaaatgcat agcattaatc gtcagcatgg ctgttgttat gttcgccata tctatgtgaa
    12721 aacagaaggt aatgcagaag ctggttttct tgacctggag aaaagtcgtc gccgcttgcg
    12781 tcgcgataaa gcgattaatc atgacttccg ccagctggaa aaatatctgg agccaatccc
    12841 caaagcggac tgggagcagg tgaaagcgta ttactacgcc atgtaatcgt tgtaggccag
    12901 ataagacgca taagcgttgt atctggcact acaaccaatt cacatctcga tttcaatatc
    12961 gccttttgcc cggcaacaac agggcaaaat ttcccccggc tgaataaagg ctaacggttc
    13021 ggcaatccag tcaacctgac ctgcaaccag acgggtgcga caggagccgc agtaaccttc
    13081 gcgacactga tactcaaccg ccacattgtg ggattccagc gccgccagaa gggaagggtg
    13141 ttcatcctgg cacagcagtt gtgtgccagt gatgcgcagg gtaacgcggg ccatcagagt
    13201 tggaagttac tcaaatcgtc ggtgtccact tccgcgtcaa tctgcccgac cagataagaa
    13261 ctgacttcca cttcctgcgg agcaacctgc acgttatcag acaccagcca ggtgttgatc
    13321 catgggatcg ggttggagcg cgtctggaac ggcagatcca aaccgactgc ctgcatacgg
    13381 atattggtga tgtattcaac gtactggcag agaatgtctt tattcagacc aatcatcgaa
    13441 ccgtcgcgga acagataatc cgcccagtct ttctcctgtt gagctgcctg aacaaacagg
    13501 tcatagcact cctgcttaca ctcttcggca atttccgcca tctcaggatc gtccgcgccg
    13561 ctgcgcagca gattcagcat atgctgggtg ccggtcaggt gcagggcttc gtcgcgggca
    13621 atcaggcgaa taattttggc gttgccttcc atcaattcgc gttctgcaaa tgcgaaggaa
    13681 caagcaaagc tgacgtagaa acgaatcgct tccagcgcgt taacgctcat caggcagaga
    13741 tacagttttt tcttcagctc gcgcaggcta acggtcacag ttttaccgtt aacggtgtgg
    13801 gtgccttcgc ccagaaggtg ccagtagctg gtcatttcga tcagttcatc gtaatagctg
    13861 gagatccctt ccgcacgttt ctggatctgc tcgttggtga cgatatcgtc aaacacaaca
    13921 gacggatcgt taacgatatt acgaatgata tgagtatagg aacgggaatg aatcgtttct
    13981 gagaacgccc aggtttcgac ccaggtttcc agttccggaa tagaaataag cggcaatagc
    14041 gccacgttcg gactacgacc ctgaatggag tccagcagcg tctgatattt caggttgctg
    14101 ataaagatgt gtttttcgtg ctccggcagc gcctggtaat cgatacggtc gcgggagacg
    14161 tcaacttctt ccggacgcca gaagaaagag agctgctttt cgatcagctt ttcgaagatg
    14221 tcatattttt gctgatcgta gcgagccacg ttgaccggct gaccaaaaaa catcggttct
    14281 ttaagctgat catttttcgt ctgtgaaaag gtggtatatg ccatgagtgt gtcctgtggt
    14341 tttattaccc ctcaccctaa ccctctcccg caaggggaga ggggacggtt tggtgcaaag
    14401 gctgggggat tatcagatct tacatgcgcc gctttcgcag ccatcgtcct ggattgacgg
    14461 caccagatcg tcctgcgcgt cttcagcgcc gtcacgggtg ttctgataat acagcgtttt
    14521 gaccccgaat ttgtaggcgg tgagcaggtc tttcagcaac tgctgcatcg gcacttttcc
    14581 tgacgggaaa cgtgacggat cgtagttggt gttagcagag atcgactgat cgataaattt
    14641 ctgcatgata cctaccagtt gcaggtagcc atcgttaccc ggcatttccc acagcagctc
    14701 ataggcgtcg tgcaggtgct cgtagtccgg caccacctgg cgcaaaatac cgtctttcga
    14761 cgctttgatg ctgacgtaac cgcgcggcgg ttcaataccg ttagtggcgt tagagatctg
    14821 cgaagaggtc tcggacggca tcagggcaga aagcgtggag ttacgcaggc cgtgcgtttt
    14881 gattgattca cgcaatgctt cccagtcgta atgcagcggc tcattagcga tggcatccag
    14941 atctttctta taggtatcga tcggcaggat ccctttcgcg taagtggttt cgttaaacca
    15001 cgggcacgcg ccttgctctt tagccagctc attagacgct ttcagcaggt aatactgaat
    15061 cgcttcgaag gttttatgcg tcaggttgtt ggcgctgccg tcggagtagc gtttaccgtg
    15121 cttcgccaga tagtaagcga agttaatcac accaataccc agcgtacgac gccccatcgc
    15181 tccacgtttg gcggccggga tcgggtaatc ctgataatcc agcagcgcgt caagtgcacg
    15241 aaccgccaga attgccagct cttccagttc atccaggcta ttaattgcgc ccaggttgaa
    15301 agcagacagc gtacacagcg cgatttcacc gttctcgtcg ttgacgtcgt tcagcggttt
    15361 ggtcggcagg gctatctcca ggcacaggtt agactgacgc actggcgcga tggccggatc
    15421 aaacgggcta tgggtattgc agtggtcaac gttctgaata tagatacgac cggtagacgc
    15481 acgttcctgc atcatcagcg agaacagctc aacggctttc acacgctgct tgcggatgct
    15541 gtcgtctttc tcatatttgg tatacaggcg ttcaaactct tcctgatcgg cgaagaatgc
    15601 gtcgtacagc cccggtacgt cggacgggct gaacagggtg atatcttcac ctttcagcag
    15661 gcgggtatac atcagtttgt tgatctgtac cccgtagtcc atatggcgca cgcggttgcc
    15721 ttccacacca cggttgtttt tcaacaccag caggctttcc acttccagat gccacatcgg
    15781 gtagaacagc gttgccgcac cgccgcgcac gccgccctga gagcaggatt tcaccgctgt
    15841 ctggaaatgt ttgtagaacg gaatacagcc ggtatggaac gcttcaccac cgcgaatcgg
    15901 gctacccagc gcacgaatac gcccggcgtt gatgccgatc ccggcacgct gggaaacgta
    15961 tttcacaatc gcgctggagg tagcgttgat ggaatccaga ctgtcaccgc actcgatcag
    16021 tacgcaggag ctgaactgac gagtcggggt acgcacgccg gacatgattg gcgtcggcag
    16081 cgaaatttta aatgtggaaa ccgcgtcgta aaaacgcttc acatattgca ggcgcgtttc
    16141 acgcgggtag ttcgagaaca ggcacgcggc aaccagaata taaaggaact gggcgctttc
    16201 gtagatttcg ccggtcacgc ggttctgtac cagatatttg ccttccagct gcttaacggc
    16261 agcataagag aaggtcatat cacggtcgtg atcgataaac gtgtccatct gcttgaactc
    16321 ttcttccgtg tagtcttcca gcagatgatt atcgtatttg cccatctcga ccattttcac
    16381 cacgtggtcg tacagcgcag gcggctcaaa ctggccgtag gcttttttac gcaggtggaa
    16441 gatcgccagg cgcgcggcga gatactgata atccggcgca tcacgggaga tcaggtctgc
    16501 ggcagccttg ataatggttt cgtggatgtc agaggtcttg ataccgtcat aaaactgaat
    16561 gtgggagcgc agctcgacct gggaaatcga aacgttatgc agtccttctg ccgcccaatc
    16621 cagaacgcga tggattttgt cgagattgat gcgctctgtg ctaccgtcgc gctttgtcac
    16681 cagcagattc tgattcatgt atgtcgtacc tgtttttgga attctttccg caatagtttc
    16741 atgcagacta cctgtagtac gggaagctgc ttagaacact atatataggg ggtatgtttg
    16801 ggattcactg caagatagtg tgaaaatggc cctcttgcaa gtgcataact ttgtggataa
    16861 ctcaggaagg aaaaagtggc tttcgcgcac cttaggtcag acaaggtgtc cgggaaagtc
    16921 aatgggaaga gaaaaatttg ttaaaaataa ctgttcggcg atttcttgaa cggcagaata
    16981 ggttggataa attgatatag atggtttatt aatctttttg ctaatgattg caaaaattga
    17041 tctaagcacg agtcatcaca taatctgatg tatcagttgt ggtcaatata taagcgaatg
    17101 taagcgattg ttgatgtcga aatggttgtt ttctattcgg ttattgttaa a
//
LOCUS       DAPGUL010000098        17011 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.100, whole genome shotgun sequence.
ACCESSION   DAPGUL010000098 DAPGUL010000000
VERSION     DAPGUL010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17011)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17011)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17011
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.100"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            142..1275
                     /gene="ompN"
                     /locus_tag="RHX21_003428"
     CDS             142..1275
                     /gene="ompN"
                     /locus_tag="RHX21_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpN"
                     /protein_id="HDV1988572.1"
                     /translation="MKSKVLALLIPALLAAGAAHAAEVYNKDGNKLDLYGKVDGLHYF
                     SDNSAKDGDQSYARLGFKGETQINDQLTGYGQWEYNIQANNTESSKNQSWTRLAFAGL
                     KFADYGSFDYGRNYGVMYDIEGWTDMLPEFGGDSYTNADNFMTGRANGVATYRNTDFF
                     GLVNGLNFAVQYQGNNEGASNGQEGTNNGRDVRHENGDGWGLSTTYDLGMGFSAGAAY
                     TSSDRTNDQVNHTAAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPFGDSDYAVAN
                     KTQNFEVTAQYQFDFGLRPAVSFLMSKGRDLHAAGGADNPAGVDDKDLVKYADVGATY
                     YFNKNMSTYVDYKINLLDEDDSFYAANGISTDDIVALGLVYQF"
     gene            1416..1850
                     /gene="uspF"
                     /locus_tag="RHX21_003429"
     CDS             1416..1850
                     /gene="uspF"
                     /locus_tag="RHX21_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310024.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspF"
                     /protein_id="HDV1988573.1"
                     /translation="MNRTILVPIDISDSELTQRVISHVEAEAKIDDAEVHFLTVIPSL
                     PYYASLGLAYSAELPAMDDLKAEAKSQLEEIIKKFKLPTDRVHVHVEEGSPKDRILEM
                     AKKIPAHMIIIASHRPDITTYLLGSNAAAVVRHAECSVLVVR"
     gene            2026..2961
                     /gene="ttcA"
                     /locus_tag="RHX21_003430"
     CDS             2026..2961
                     /gene="ttcA"
                     /locus_tag="RHX21_003430"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HDV1988574.1"
                     /translation="MSQNQEISKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMV
                     CLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHVLPEYLEKLGVEYKI
                     VEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFL
                     NMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIQRFADAKAFPIIPCNLCGSQPN
                     LQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVVNGGD
                     LAFDREEIPLQPAGWQPEEDENQLDELRLNVVEVK"
     gene            complement(3090..4463)
                     /gene="dbpA"
                     /locus_tag="RHX21_003431"
     CDS             complement(3090..4463)
                     /gene="dbpA"
                     /locus_tag="RHX21_003431"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase DbpA"
                     /protein_id="HDV1988575.1"
                     /translation="MTAFSTLNVLPPAQLTNLNELGYLTMTPVQAAALPAILAGKDVR
                     VQAKTGSGKTAAFGLGLLQQIDASLFQTQALVLCPTRELADQVAGELRRLARFLPNTK
                     ILTLCGGQPFGMQRDSLQHAPHIIVATPGRLLDHLQKGTVSLDALNTLVMDEADRMLD
                     MGFSDAIDDVIRFAPASRQTLLFSATWPEAIAAISGRVQRDPLAIEIDSTDALPPIEQ
                     QFYETSSKGKIPLLQRLLSLHQPSSCVVFCNTKKDCQAVCDALNEVGQSALSLHGDLE
                     QRDRDQTLVRFANGSARVLVATDVAARGLDIKSLELVVNFELAWDPEVHVHRIGRTAR
                     AGNSGLAISFCAPEEAQRANIISDMLQIKLNWQTPPANSSIVPLEAEMATLCIDGGKK
                     AKMRPGDVLGALTGDIGLDGADIGKIAVHPAHVYVAVRQAVAHKAWKQLQGGKIKGKT
                     CRVRLLK"
     gene            complement(4941..5924)
                     /gene="zntB"
                     /locus_tag="RHX21_003432"
     CDS             complement(4941..5924)
                     /gene="zntB"
                     /locus_tag="RHX21_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZntB"
                     /protein_id="HDV1988576.1"
                     /translation="MEAIKGSDVNVPDAVFAWMLDGRGGVKPLENTDVIDEAHPCWLH
                     LNYVHHDSAQWLATTPLLPNNVRDALAGESTRPRVSRLGEGTLITLRCINGSTDERPD
                     QLVAMRVYMDGRLIVSTRQRKVLALDDVVSDLEEGTGPTDCGGWLVDVCDALTDHSSE
                     FIEQLHDKIIDLEDNLLDQQIPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPW
                     MSDDQRRRMQDIADRLGRGLDEIDACIARTGVMADEIAQVMQENLARRTYTMSLMAMV
                     FLPSTFLTGLFGVNLGGIPGGGWQFGFSIFCILLVVLIGGVALWLHRSKWL"
     gene            6179..7411
                     /gene="dgcM"
                     /locus_tag="RHX21_003433"
     CDS             6179..7411
                     /gene="dgcM"
                     /locus_tag="RHX21_003433"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415857.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcM"
                     /protein_id="HDV1988577.1"
                     /translation="MITHNFNTLDLLTSPVWIVSPFEEQLIYANSAARLLMQDLTFSQ
                     LRTGPYSVSSQKELPKYLSDLQNQHDIIEILTVQRKEEETALSCRLVLRKLTEAEPVI
                     IFEGIEAPATLGLKASRSANYQRKKQGFYARFFLTNSAPMLLIDPSRDGQIVDANLAA
                     LNFYGYNHETMCQKHTWEINMLGRRVMPIMHEISHLPGGHKPLNFVHKLADGSTRHVQ
                     TYAGPIEIYGDKLMLCIVHDITEQKRLEEQLEHAAHHDAMTGLLNRRQFYHITEPGQM
                     QHLAIAQDYSLLLIDTDRFKHINDLYGHSKGDEVLCALARTLESCARKGDLVFRWGGE
                     EFVLLLPRTPLDTALSLAETIRVSVAKVSISGLPRFTVSIGVAHHEGNESIDELFKRV
                     DDALYRAKNDGRNRVLAA"
     gene            complement(7432..7995)
                     /gene="smrA"
                     /locus_tag="RHX21_003434"
     CDS             complement(7432..7995)
                     /gene="smrA"
                     /locus_tag="RHX21_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA endonuclease SmrA"
                     /protein_id="HDV1988578.1"
                     /translation="MNLDDKSLFLDAMEDVQPLKRATDVHWHPTRNQRAPQRIDTLQL
                     DNFLTTGFLDIIPLSQPLEFRREGLQHGVLDKLRSGKYPQQASLNLLRQPVEECRKMM
                     FSFIQQAMADGLRNVLIIHGKGRDDKSHANIVRSYVARWLTEFDDVQAYCTALPHHGG
                     SGACYVALRKTAQAKQENWERHAKRSR"
     gene            complement(8325..9233)
                     /locus_tag="RHX21_003435"
     CDS             complement(8325..9233)
                     /locus_tag="RHX21_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV1988579.1"
                     /translation="MAFQVKIHQIRAFVEVARQGSIRGASRMLNMSQPALSKSIQELE
                     EGLAAQLFFRRSKGVTLTDAGESFYQHASLILEELRAAQEDIRQRQGQLAGQINIGMG
                     ASISRSLMPAVISRFHQQHPQVKVRIMEGQLVSMINELRQGELDFTINTYYQGPYDHE
                     FTFEKLLEKQFAIFCRPGHPAIGARSIKQLLDYSWTMPTPHGSYYKQLSELLDDQAQT
                     PQVGVVCETFSACISLVAKSDFLSILPEEMGCDPLHGQGLVMLPVSEILPKAAYYLIQ
                     RRDSRQTPLTASLITQFRRECGYLQS"
     gene            9409..10719
                     /gene="abgA"
                     /locus_tag="RHX21_003436"
     CDS             9409..10719
                     /gene="abgA"
                     /locus_tag="RHX21_003436"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415854.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-aminobenzoyl-glutamate hydrolase subunit AbgA"
                     /protein_id="HDV1988580.1"
                     /translation="MESLNQFVNSLAPKLSHWRRDFHHYAESGWVEFRTATLVAEELQ
                     QLGYSLALGREVVNESSRMGLPDELTLQREFERARQQGALAQWIAVFEGGFTGIVATL
                     DTGRPGPVMAFRVDMDALDLSEEQDVSHRPYRDGFASCNAGMMHACGHDGHTAIGLGL
                     AHTLKQFESGLHGVIKLIFQPAEEGTRGARAMVDAGVVDDVDYFTAVHIGTGVPAGTV
                     VCGSDNFMATTKFDAHFTGTAAHAGAKPEDGHNALLAAAQATLALHAIAPHSEGASRV
                     NVGVMQAGSGRNVVPASALLKVETRGASDVINQYVFDRAQQAIQGAATMYGVGVETRL
                     MGAATASSPSPQWVAWLQSQAAQVAGVNQAIERVEAPAGSEDATLMMARVQQHQGQAS
                     YVVFGTQLAAGHHNEKFDFDEQVLAIAVETLARTALNFPWTRGI"
     gene            10719..12164
                     /gene="abgB"
                     /locus_tag="RHX21_003437"
     CDS             10719..12164
                     /gene="abgB"
                     /locus_tag="RHX21_003437"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-aminobenzoyl-glutamate hydrolase subunit AbgB"
                     /protein_id="HDV1988581.1"
                     /translation="MQEIYRFIDDAIEADRQRYTDIADQIWDHPETRFEEFWSAEHLA
                     SALESAGFTVTRNVGNIPNAFIASFGQGKPVIALLGEYDALAGLSQQAGCAQPTSVTP
                     GENGHGCGHNLLGTAAFAAAIAVKKWLEQYGQGGTVRFYGCPGEEGGSGKTFMVREGV
                     FDDVDAALTWHPEAFAGMFNTRTLANIQASWRFKGIAAHAANSPHLGRSALDAVTLMT
                     TGTNFLNEHIIEKARVHYAITDSGGISPNVVQAQAEVLYLIRAPEMTDVQHIYDRVAK
                     IAEGAALMTETTVECRFDKACSSYLPNRTLENAMYHALSHFGTPEWNSEELAFAKQIQ
                     ATLTPNDRQNSLNNIAATGGENGKVFALRHRETVLANEVAPYAATDNVLAASTDVGDV
                     SWKLPVAQCFSPCFAVGTPLHTWQLVSQGRTSIAHKGMLLAAKTMAATTVNLFIDSGL
                     LQECQQEHQQVTDTQPYHCPIPKNVTPSPLK"
     gene            12201..13727
                     /gene="abgT"
                     /locus_tag="RHX21_003438"
     CDS             12201..13727
                     /gene="abgT"
                     /locus_tag="RHX21_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415852.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-aminobenzoyl-glutamate transporter"
                     /protein_id="HDV1988582.1"
                     /translation="MSMSSIPSSSQSGKLYGWVERIGNKVPHPFLLFIYLIIVLMVTT
                     AILSAFGVSAKNPTDGTPVVVKNLLSVEGLHWFLPNVIKNFSGFAPLGAILALVLGAG
                     LAERVGLLPALMVKMASHVNARYASYMVLFIAFFSHISSDAALVIMPPMGALIFLAVG
                     RHPVAGLLAAIAGVGCGFTANLLIVTTDVLLSGISTEAAAAFNPQMHVSVIDNWYFMA
                     SSVVVLTIVGGLITDKIIEPRLGQWQGNSDEKLQTLTESQRFGLRIAGVVSLLFIAAI
                     ALMVIPENGILRDPINHTVMPSPFIKGIVPLIILFFFVVSLAYGIATRTIRRQADLPH
                     LMIEPMKEMAGFIVMVFPLAQFVAMFNWSNMGKFIAVGLTDILESSGLSGIPAFVGLA
                     LLSSFLCMFIASGSAIWSILAPIFVPMFMLLGFHPAFAQILFRIADSSVLPLAPVSPF
                     VPLFLGFLQRYKPDAKLGTYYSLVLPYPLIFLVVWLLMLLAWYLVGLPIGPGIYPRLS
                     "
     gene            13738..14253
                     /gene="ogt"
                     /locus_tag="RHX21_003439"
     CDS             13738..14253
                     /gene="ogt"
                     /locus_tag="RHX21_003439"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDV1988583.1"
                     /translation="MLRLLEEKIATPLGPLWVICDEQFRLRAVEWEEYSERMVQLLDI
                     HYRKEGYERISATNPGGLSDKLRDYFAGNLSIIDTLPTATGGTPFQREVWKTLRTIPC
                     GQVMHYGQLAEQLGRPGAARAVGAANGSNPISIVVPCHRVIGRNGTMTGYAGGVQRKE
                     WLLRHEGYLLL"
     gene            14448..15200
                     /gene="fnr"
                     /locus_tag="RHX21_003440"
     CDS             14448..15200
                     /gene="fnr"
                     /locus_tag="RHX21_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007849744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="HDV1988584.1"
                     /translation="MIPEKRIIRRIQSGGCAIHCQDCSISQLCIPFTLNEHELDQLDN
                     IIERKKPIQKGQTLFKAGDELKSLYAIRSGTIKSYTITEQGDEQITGFHLAGDLVGFD
                     AIGSGHHPSFAQALETSMVCEIPFETLDDLSGKMPNLRQQMMRLMSGEIKGDQDMILL
                     LSKKNAEERLAAFIYNLSRRFAQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRF
                     QKSGMLAVKGKYITIENNDALAQLAGHTRNVA"
     gene            15352..16302
                     /gene="uspE"
                     /locus_tag="RHX21_003441"
     CDS             15352..16302
                     /gene="uspE"
                     /locus_tag="RHX21_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspE"
                     /protein_id="HDV1988585.1"
                     /translation="MAMYQNMLVVIDPNQDDQPALRRAVYLHQRIGGKIKAFLPIYDF
                     SYEMTTLLSPDERTAMRQGVISQRTAWIHEQAKYYLNAGVPIEIKVVWHNRPFEAIIQ
                     EVISGGHDLVLKMAHQHDRLEAVIFTPTDWHLLRKCPSPVWMVKDQPWPEGGKALVAV
                     NLASEEPYHNALNEKLVKETIELAEQVNHTEVHLVGAYPVTPINIAIELPEFDPSVYN
                     DAIRGQHLLAMKALRQKFGINENMTHVEKGLPEEVIPDLAEHLQAGIVVLGTVGRTGI
                     SAAFLGNTAEQVIDHLRCDLLVIKPDQYQTPVELDDEEDD"
     gene            complement(16352..16609)
                     /locus_tag="RHX21_003442"
     CDS             complement(16352..16609)
                     /locus_tag="RHX21_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2534 family protein"
                     /protein_id="HDV1988586.1"
                     /translation="MIMAKLKSAKGKKFLFGLLAVFIIAASVVTRATIGGVIEQYNIP
                     LSEWTTSMYVIQSSMIFVYSLVFTVLLAIPLGIYFLGGEEQ"
     gene            16853..>17011
                     /locus_tag="RHX21_003443"
     CDS             16853..>17011
                     /locus_tag="RHX21_003443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel protein MscS"
                     /protein_id="HDV1988587.1"
                     /translation="MIAELFTNNALNLVIIFGSCAALILMSFWFRRGNRKRKGFLFHA
                     VQFLIYTII"
BASE COUNT         4337 a         4223 c         4138 g         4313 t
ORIGIN      
        1 tttcagagga attatttgat taaggtttta cttaaggcgt aacaaatgat atttatcggc
       61 taactgaact tctcctttag gatgttttca ctccccgaaa tggggataaa aggcaaataa
      121 aataactaaa ggatttattc aatgaaaagc aaagtactgg cacttttaat tcctgccctg
      181 ctcgccgcag gtgctgcaca tgcagccgaa gtttataata aagacggcaa caaattagat
      241 ctgtatggca aagttgatgg cctgcattat ttttctgata attcggcgaa agatggcgac
      301 cagagctatg cgcgtctggg ttttaaaggc gaaacccaaa ttaacgatca actcactggc
      361 tacggtcaat gggaatacaa tattcaggca aacaacactg aatcttcaaa aaaccagtca
      421 tggacccgtc tggcatttgc cgggctgaaa tttgcagatt acggttcttt cgattacgga
      481 cgtaattatg gcgtaatgta cgacatcgaa ggctggaccg atatgctgcc tgaatttggc
      541 ggtgactctt ataccaatgc agacaacttt atgactggtc gagccaatgg cgtcgcgact
      601 tatcgtaata ctgatttctt cggtctggta aatggtctga acttcgcggt gcagtatcaa
      661 ggtaacaacg aaggtgccag taatggtcag gaaggcacca acaacggacg tgatgttcgc
      721 catgaaaacg gtgacggctg gggtctttcc acaacatatg atttaggcat gggctttagc
      781 gctggtgcgg catacacctc ttctgaccgc accaatgatc aggttaacca tactgcggcg
      841 ggtggtgata aagcagacgc gtggactgct gggctaaaat acgatgctaa caatatttac
      901 ctggcaacca tgtattcaga aacgcgtaat atgaccccgt ttggcgacag cgattatgct
      961 gttgcaaaca aaacccagaa ctttgaagtc actgcacagt accagtttga ttttggtctg
     1021 cgtccggcag tctctttcct gatgtctaaa ggccgtgacc tgcacgctgc cggtggtgca
     1081 gacaacccgg caggtgttga tgataaagat ctggttaaat acgccgatgt tggcgcgact
     1141 tactatttca ataaaaacat gtccacttat gttgactata aaatcaacct gttggatgaa
     1201 gatgacagtt tctacgctgc caatggcatc tctaccgatg atattgtcgc tttaggtctg
     1261 gtttatcagt tctaaatcct cctgcccgct gttatggcgg gctttttctg cttattcttc
     1321 ctcctttgat ctaaattaaa aatgtgaact ccgtcattac acaaaaagtg tcatctggcg
     1381 ttacacttta tgcggatact aaaacaggag gttttatgaa cagaacgatt cttgtcccta
     1441 tcgatatttc cgattcagaa ttaactcaac gcgtgattag ccacgttgag gcagaggcaa
     1501 agattgatga tgcagaggtt catttcctga cggtaatacc ttcactgccc tactatgcct
     1561 ctctgggttt agcgtattcc gcagaattac cggcaatgga tgacctgaaa gcggaagcca
     1621 aatcgcaact ggaagagatc attaaaaaat ttaaactgcc aaccgacaga gtgcatgtcc
     1681 atgttgagga aggctcgccc aaagaccgca ttctggaaat ggcgaagaag atccccgctc
     1741 atatgatcat cattgcttcc catcgaccgg atatcaccac ttatctgctc ggttccaacg
     1801 ccgcagctgt agtgcgtcac gcagagtgct ccgtgctggt tgtgcgctga cactaacgcc
     1861 cgcacattgc tgcgggcttt ttgattcatt tcgcaaatgt gctgacattt tcccctctaa
     1921 tccgtaccat acacgccaca gtttttatat cagatttctt atgctgggcg ttccggcatg
     1981 acgcatactc ttctgatgcc atataacgaa ttgagtcgct tttaaatgtc gcaaaatcaa
     2041 gaaattagta agaaagaaca atacaacctg aacaaattac aaaaacgtct gcgtcgtaac
     2101 gtgggcgaag ccattgctga cttcaatatg attgaagaag gcgatcgcat catggtttgc
     2161 ctctccgggg gtaaagacag ctataccatg ctggagattc tgcgcaattt gcagcaaagc
     2221 gcgccaatca atttttcgct ggtggctgtt aacctcgatc aaaagcaacc gggcttcccg
     2281 gaacacgttc tgcccgagta tcttgaaaag ctgggcgttg agtacaagat tgttgaagag
     2341 aatacttacg gtatcgtgaa agagaagatt ccagagggca aaaccacttg ctcactgtgt
     2401 tctcgccttc gtcgcggtat cctttatcgt accgcaacgg aactgggggc gacgaagatc
     2461 gcgttgggtc accatcgtga cgatatcctg caaacgttgt tcttaaatat gttctacggc
     2521 ggcaagatga aaggtatgcc tccgaaactg atgagcgatg atggcaaaca tatcgttatt
     2581 cgtccgctgg cctactgccg cgagaaagat attcagcgat ttgccgatgc aaaagcgttc
     2641 ccgattattc cgtgcaacct gtgcggttca cagcctaacc tgcaacgtca ggtgattgct
     2701 gacatgttgc gtgactggga taaacgttat ccagggcgta tcgagacgat gttcagcgcg
     2761 atgcagaatg tggtgccgtc gcatctgtgc gataccaacc tgttcgattt caaaggcatt
     2821 acccacggtt ctgaagtggt taacgggggt gatctggcgt ttgatcgcga agagatccca
     2881 ctacaaccgg cgggctggca gccagaagaa gatgaaaatc agttggatga gttacggctg
     2941 aatgtggttg aagtgaaata accaggatag cgcccgatgc gcaagcgtat cgggctactc
     3001 ttatggaggc cggataagac gcggccagcg tcgcatccgg caatcccgca taagatgttt
     3061 actcttgcac ccggcaattc aacatttcat tattttaata accgcacccg gcacgttttt
     3121 cctttaatct tcccgccctg taactgtttc catgctttat gagcaacagc ctgacgcacc
     3181 gcgacataga catgcgccgg atgcacggcg attttgccaa tatctgcgcc atcaagcccg
     3241 atatctcctg tcagtgcacc taatacatca cccgggcgca ttttggcttt tttcccgcca
     3301 tcgatacaca acgttgccat ttctgcttcc agcggcacaa tggaactatt agctggcggc
     3361 gtttgccagt taagttttat ctgcaacatg tcagaaatga tattggcccg ctgtgcttct
     3421 tccggagcac agaaactgat cgccagaccg ctatttcctg cacgagctgt acgaccgatg
     3481 cgatgtacat gaacttcagg gtcccacgcc agctcaaagt tcaccaccag ctcaagcgat
     3541 ttaatatcca gaccacgcgc agcaacatca gtagcaacca gtacacgggc gctaccgtta
     3601 gcaaaacgta ccagagtctg atcgcgatcg cgttgctcca gatcgccgtg taacgacaat
     3661 gcactttgcc ctacttcatt cagcgcgtcg cagacagcct ggcaatcttt tttggtattg
     3721 caaaacacca cgcaagagga tggctgatgc aagcttaata accgttgcaa cagaggaatt
     3781 ttgcctttgc tggatgtctc ataaaattgt tgttcaatgg gtggcaaagc atctgttgag
     3841 tcaatttcaa tcgccaaagg atcgcgttgc actcgtccgc tgattgcggc gatggcttcc
     3901 ggccaggttg ccgaaaacag aagcgtctgt cgagatgcag gcgcaaaacg gatgacatca
     3961 tcaatggcat cgctaaatcc catatccagc atgcggtcgg cctcatccat caccaaagta
     4021 ttcagcgcat ccagtgatac cgtgcctttt tgcaagtgat ccagcaaacg acccggcgtt
     4081 gccacgataa tatgcggcgc atgttgcaac gaatcacgct gcataccgaa cggttgacca
     4141 ccgcataacg tcaaaatttt ggtatttggc agaaaacgcg ccagccgacg caattcacct
     4201 gccacctgat ccgccagttc acgcgtagga cacagcacta aagcctgggt ttgaaatagc
     4261 gacgcatcaa tttgctgtaa caagccgagg ccaaaagccg ccgttttgcc gctgccggtt
     4321 ttcgcctgca cgcgaacatc ttttccggca aggatcgccg gaagcgcggc ggcctgcacc
     4381 ggcgtcatgg ttaaataacc caactcatta aggttcgtga gttgggcggg aggcaaaaca
     4441 ttcagggtag aaaaagcggt cacaatctat tctcgtggtc atcgacgcaa agttagcagg
     4501 cgcgtatcct cgcagatcta cgctcacgat gcgacaattt aatcggttct tcatcaggtg
     4561 gtgggtcagg catgggttgc gggcgaggga tcggatcggg cactggaaca ggatcgccag
     4621 gaatcggttc agggacagga atttgcaaat aaataagtgt cgtcatattt ccctccggtc
     4681 attgggtgga ctcttaaagg gtagacgctg ataaataaca ggcaaaaaaa agccgactca
     4741 tcaaagtcgg cgtcgtacga atcaattgtg ctatgcagta attcaaaaaa ggaagtaaga
     4801 caatatggag cgcaacgccc atcgcttgac gttgcattca cctgcaaggg agatattgcc
     4861 ctgaatgggt agagagttta ttgacttcgc tcaaactttg cggcgttttt gtatacagac
     4921 agccggaaaa attgcttttg ttacaaccat ttactacggt gcaaccataa agcaacacca
     4981 ccaataagaa caactaacag aatacaaaaa attgaaaatc cgaattgcca cccgccgcca
     5041 gggatcccac caaggttgac gccaaataac cctgtcagaa aggtactggg taaaaagacc
     5101 attgccatca atgacattgt ataggtacga cgagctaaat tttcctgcat cacctgagcg
     5161 atttcatccg ccatcacgcc agtccgtgct atacaggcgt cgatttcgtc aagaccgcgc
     5221 ccaaggcgat cggcaatatc ctgcatccga cggcgttggt catcgctcat ccacggcaaa
     5281 cgttcactgg caagacgagc ataaacatca cgttgcggtg ccatatagcg acgcatcacg
     5341 attaattgtt tgcgcagcag agccaggaat ccacgcggtg gaatttgctg atcaaggaga
     5401 ttatcttcaa ggtcgataat tttatcgtgc agctgctcga taaattcgct ggaatgatcg
     5461 gtcaacgcat cgcacacatc caccagccac cctccgcaat cggtcggacc cgtgccctct
     5521 tccagatcgc tcaccacatc gtccagcgcc agcactttgc gttgtcgggt cgaaacaatt
     5581 aaccgcccgt ccatatatac acgcatggcg accagttgat cggggcgttc atcggtgctg
     5641 ccgtttatac agcgcaatgt aatcagcgtg ccttcaccga gacggctgac tcggggccgc
     5701 gtgctctcgc ccgccagcgc atcacgtacg ttattgggaa gcagcggtgt tgtcgccagc
     5761 cattgggcgc tatcatggtg tacataatta aggtggagcc agcagggatg cgcttcatca
     5821 atcacatctg tattttccag cggtttaacg ccgcctctac catccagcat ccaggcaaat
     5881 actgcatccg ggacattaac gtccgatccc ttaatcgctt ccacagtgcc tccatcatca
     5941 acgcattatt ttgtagtcta gccttctggc cctgttacgc aacatctcat caccccatta
     6001 ccctgaaatg attaataaaa ttctgtctaa attgaataca aaaagcaaaa tgcttttccg
     6061 tatacaaacc gtgtgaagtg ttaaatagcg tctatcatta tcagaattat ctgatcatat
     6121 gacatggctt ttttgcgatc ggatagcaac aaaaattgat aaaaataacg ggatctcaat
     6181 gattacgcac aacttcaata ccctggactt actcaccagt cctgtctgga tcgtttcgcc
     6241 ctttgaggaa cagttaattt atgccaatag cgcggcgcga ctgttgatgc aagacctcac
     6301 gtttagtcag ctacgaaccg gtccctattc cgtctcctca caaaaagaac tgccgaaata
     6361 cctctccgat ctgcaaaacc aacacgatat tatcgaaatc ctcactgttc agcgtaaaga
     6421 agaggaaaca gcattaagct gtcggcttgt tttgcgaaag ctgacagaag cagaaccggt
     6481 gattattttc gaaggtatcg aagcgccggc aacgctgggt ttaaaagcca gtcgctcggc
     6541 aaattatcag cgcaaaaaac aaggttttta tgcgcgcttt tttctgacta actctgcacc
     6601 aatgttgttg attgacccct cacgagatgg ccaaatcgtc gatgctaacc tcgccgcgct
     6661 caatttctat ggttataacc atgaaacgat gtgccagaaa catacctggg aaattaatat
     6721 gctcgggcgt cgcgtcatgc ctatcatgca tgaaatttcg catttacccg gcggtcataa
     6781 acctttgaat tttgttcata aactggcgga tggatctact cgtcatgtgc agacctatgc
     6841 cgggccgatt gaaatttatg gcgacaagct catgttatgt attgtgcatg atattactga
     6901 gcaaaaacgg ctggaggagc agctggaaca tgctgctcac catgacgcga tgaccggatt
     6961 actgaatcgg cgacagtttt atcacattac ggaaccaggc caaatgcagc acctcgccat
     7021 cgcccaggat tacagcttgt tgctcatcga caccgatcgt tttaaacaca ttaacgatct
     7081 ctatgggcat tctaaaggtg atgaggtgtt atgcgccctc gcccgcaccc ttgaaagttg
     7141 cgctcgcaaa ggcgatttgg tgtttcgttg gggaggcgaa gagtttgtct tattgctacc
     7201 aagaacccca cttgataccg cgctttcgct ggctgaaact atccgtgtaa gcgtggcaaa
     7261 agtgagtatt tcgggcttac cacgctttac cgtcagcatt ggtgtggcgc atcacgaagg
     7321 aaatgaaagc atcgatgaac tgtttaaacg cgttgatgat gctttgtatc gggcgaaaaa
     7381 tgatggacgc aaccgcgtgc tggcggcata agccgcggat gcgtctcgag atcaacgact
     7441 gcgcttagcg tggcgctccc agttttcttg cttcgcctgc gccgttttac gtagtgcgac
     7501 gtaacacgcc ccgctgccgc catgatgcgg tagcgcagtg caatatgcct gaacatcatc
     7561 aaattcggtc agccagcgcg ccacatagct gcggacaata ttggcatgcg atttatcatc
     7621 ccgtcctttg ccatgaataa tcagcacgtt acgcaaacca tcagccatgg cttgttgaat
     7681 gaaactgaac atcattttgc ggcactcttc caccggctgg cgcaaaagat tcaggctcgc
     7741 ctgttgcgga tatttaccac tgcgcagctt atccagcacc ccatgttgca acccttcccg
     7801 ccgaaactcc agcggctgac ttagtgggat gatgtcgaga aatccggtgg tgaggaaatt
     7861 atcaagctgc agcgtgtcga tacgctgcgg cgcacgttgg ttacgcgttg gatgccagtg
     7921 gacatcggta gcacgtttca gcggctggac atcttccatg gcgtcaagaa acagcgattt
     7981 gtcgtcaagg ttcatgttac atcctcccgc aattaagagc gcgatatgat aaccagaccg
     8041 ggtcggtcca acaacgtatt acccaaaatt ccagtaataa gttccaaata ttgccgatat
     8101 tttaagcaaa atgcttatgc atgattattc attcacgata ttaataatgt aacttatatt
     8161 ttcgtgaaat ctgtcactga agaaaattgg caactaaagg ttaaaaccgt tataacacag
     8221 tcaccggcgc agaggagaca atgccggatt taagacgcgg atgcactgct gtgtgtactg
     8281 tagagtctgg cggatgtcga cagactctat ttttttatgc agttttaact ttgcagatag
     8341 ccgcattctc gccggaattg cgtgattaat gacgcggtca gtggtgtctg gcgactatca
     8401 cgccgctgaa tcaaataata ggccgctttc ggtaaaattt cgctaaccgg caacatcacc
     8461 agcccctgtc cgtgcaaggg atcgcagccc atttcttcag gcagtatgct gagaaaatcg
     8521 ctttttgcca ccagactgat acaggctgag aacgtctcgc agactacacc gacctgtggc
     8581 gtttgcgcct gatcgtcaag caattcgctc aactgtttgt agtagctgcc gtgtggcgtc
     8641 ggcattgtcc agctgtaatc cagtaactgt ttgatcgaac gggcaccaat ggcggggtgt
     8701 cccgggcggc aaaagatcgc gaattgcttt tccagtaatt tctcaaaagt aaattcgtgg
     8761 tcgtacggtc cctgataata ggtattgatg gtgaaatcca attctccctg acgcaattca
     8821 ttaatcatcg acaccagttg cccttccata atgcgtactt ttacctgcgg atgctgctga
     8881 tgaaaacgag atatgacagc tggcatcaga ctgcgggaaa tactggcccc catgccgata
     8941 ttaatctgcc ctgccagttg cccttgtcgt tggcgaatat cctcttgggc tgcgcgcagt
     9001 tcttcaagaa taagactggc gtgctgataa aaactttcac cggcatcagt taacgtcacg
     9061 cctttactac ggcgaaaaaa gagttgcgcc gctaatcctt cttccagctc ctgaatagat
     9121 ttactcagtg ccggttgcga catattcaac attcggctcg ctccgcgaat gctgccctga
     9181 cgagccactt caacaaaagc acgaatttga tgaattttta cctgaaaagc catgacgcca
     9241 ccgataaccg ttatttatca gaccaaagaa actggcatct actttaatgc agatgattgt
     9301 gtcagggtaa tttatgaacg gttaaaactg tgaaaaatca gttagtgata agtaaaaact
     9361 atcgctacgt gaaccgggtc acacttttta ctgatgacgg gaaaggttat ggagtctttg
     9421 aatcaatttg ttaattcgct tgccccaaaa ttatcgcact ggcgacgtga ttttcatcac
     9481 tatgcagagt ctggctgggt ggaattccgc actgccaccc ttgttgcgga agaattgcag
     9541 cagctcggct attcactggc gctgggccgc gaagtagtta atgaaagtag ccggatggga
     9601 ctacctgatg aactcactct acaacgcgaa ttcgagcgcg ctcgtcaaca gggtgcgcta
     9661 gcacaatgga ttgcggtttt tgaaggtggt ttcactggta tcgtcgccac cctggatacc
     9721 ggtcgccccg gtccggtgat ggctttccgt gtcgatatgg acgcgctgga tctcagtgaa
     9781 gagcaggatg tcagccatcg cccctaccgc gacggttttg cgtcatgtaa cgccggaatg
     9841 atgcatgcct gtggtcatga tggacatacc gccattgggc ttgggctggc gcataccctt
     9901 aaacaattcg agtccggact acatggcgtc atcaaactga tttttcagcc tgcagaggaa
     9961 ggtacgcgtg gcgcgcgggc gatggtcgat gcaggtgtcg tagatgatgt tgattatttt
    10021 actgccgtgc acattggcac tggcgtacct gcgggcaccg tggtgtgcgg cagtgataat
    10081 tttatggcaa ccaccaaatt tgacgcgcac ttcaccggta ccgccgctca cgcaggcgca
    10141 aaaccagaag acggtcacaa tgccttgttg gcggcagcac aagccactct tgcactgcat
    10201 gcaatcgccc cgcacagcga aggagcttcc agagtaaacg tgggcgttat gcaggcagga
    10261 agcggtcgta acgttgttcc tgcctcggcg ttgctgaaag tggaaacacg cggggccagc
    10321 gacgtcatta atcaatatgt ttttgaccgt gcacaacaag cgattcaggg cgcagcaacc
    10381 atgtatggtg tcggcgttga aactcgtctg atgggtgcag ctaccgccag ttctccttcg
    10441 ccgcaatggg tcgcatggtt gcaaagtcag gcggctcagg tcgcgggggt caatcaggcc
    10501 attgaacgtg ttgaagcgcc tgcgggttcc gaagatgcca cattaatgat ggcccgcgtg
    10561 cagcaacatc aagggcaagc ctcctacgtg gtgtttggca cacagctggc ggcaggtcat
    10621 cacaacgaaa aattcgattt tgacgagcag gttctcgcta ttgccgtcga aacgctggcg
    10681 cgcaccgcgc tcaattttcc ctggacgcga ggtatctgat gcaggaaatc tatcgtttta
    10741 tcgacgatgc gattgaagcc gatcgccaac gttataccga tattgccgat caaatctggg
    10801 atcatccaga aacacgtttt gaagagttct ggtcagcgga gcatctggct tcggcgctgg
    10861 aatctgcagg cttcaccgtt acccgcaacg taggcaatat cccaaatgcc tttattgctt
    10921 cgtttggtca aggcaaaccg gttatcgccc tgctgggaga atatgacgcc ctggcaggtt
    10981 taagtcagca agcaggttgc gcgcaaccta catccgtgac gcccggtgaa aatggtcacg
    11041 gttgcggaca caatttgctg ggaaccgccg cctttgccgc tgcaatagcc gtcaagaaat
    11101 ggctggaaca atatgggcaa ggcggcacag tgcgctttta tggttgtcct ggcgaagaag
    11161 gcggctcggg taaaacgttc atggtccgcg agggggtatt tgatgatgtg gatgcggcac
    11221 tcacctggca cccggaagcc tttgccggta tgttcaatac ccgcacgctg gcaaacattc
    11281 aggcatcatg gcgctttaaa gggatcgcag cacatgccgc gaattcccct catttgggac
    11341 gcagcgccct tgatgccgta acgttgatga ccactggcac caacttcctc aacgaacata
    11401 ttattgaaaa agcgcgcgta cactatgcca tcacagatag cggcgggatc tcgcccaacg
    11461 tggtccaggc gcaggcagaa gtgctttatc ttatccgtgc ccccgaaatg accgacgtgc
    11521 agcatattta tgatcgggtc gccaaaatcg ccgaaggtgc ggcattgatg accgaaacca
    11581 cggttgaatg ccgcttcgac aaagcctgtt ccagttatct cccgaatcgc accttagaaa
    11641 atgccatgta ccatgcccta tcccattttg gtaccccgga atggaactcc gaagaactgg
    11701 cttttgcgaa acaaattcag gctacgctca cccccaacga tcggcaaaac agtctgaata
    11761 atatcgccgc aaccggtggc gaaaacggca aggtttttgc actacgtcat cgtgaaacgg
    11821 tactggcgaa tgaggtcgct ccatatgccg ccaccgataa cgtgcttgcg gcatcgactg
    11881 atgtcggcga cgtcagttgg aaactgcctg ttgcccagtg tttcagcccc tgttttgccg
    11941 tcggtacacc gctacatacg tggcaactgg ttagccaggg gcgaacatct attgctcata
    12001 aaggaatgct gctggcggcg aaaactatgg cagcaaccac agtcaatctc ttcattgatt
    12061 cagggctatt gcaagaatgc caacaagagc atcagcaagt tacggacacg caaccgtatc
    12121 actgccctat cccgaaaaac gtgacaccgt cacctttaaa ataacaacaa caacgcaaac
    12181 acaacaaccg aggaatgccc atgagtatgt catccatacc gtcgtcctcc caatccggga
    12241 agctctatgg ctgggtcgaa agaattggta acaaggttcc ccatcctttt ttgctcttta
    12301 tctatttgat aatcgtactc atggtgacga cggcaatttt gtcagccttt ggcgtcagtg
    12361 cgaaaaaccc gaccgatggt acgccggtgg tggtgaaaaa cctgctcagt gtggaaggat
    12421 tacactggtt tttacccaat gtgattaaaa actttagcgg ttttgctcca cttggagcga
    12481 tcctggcgct ggttttaggt gccggcctag cggagcgcgt cggcttactg ccagcgctaa
    12541 tggttaaaat ggcatcgcat gttaatgccc gctacgccag ttatatggtg ctgtttattg
    12601 cttttttcag ccacatttct tccgatgcgg cgttagtgat catgccaccg atgggtgcgc
    12661 tgatttttct ggcggtgggc aggcatccag ttgcaggttt actggctgcc attgcaggcg
    12721 taggttgcgg ctttacggct aatttactga ttgtcacaac cgacgtgttg ctgtcgggga
    12781 tcagcacgga agcggcggct gcgttcaatc cgcaaatgca cgtcagtgta attgataact
    12841 ggtattttat ggccagctcc gtagtcgtac tgacgattgt tggcggcctg ataaccgaca
    12901 aaatcatcga gccacgatta ggtcaatggc agggaaacag cgatgagaaa ctgcagacat
    12961 tgaccgaaag tcagcgtttt ggtttacgca tagcaggtgt cgtatcgcta ctttttattg
    13021 ctgcgatcgc gctgatggtg atcccggaaa acgggatatt gcgcgatccg attaatcaca
    13081 ccgtgatgcc atcacccttt attaaaggta tcgtgccact gatcattctt tttttctttg
    13141 ttgtctcgct ggcttatggc atcgctaccc gcacaattcg acgtcaggcg gatttaccgc
    13201 atttaatgat tgaaccgatg aaagagatgg cgggatttat cgtgatggtt tttcccctcg
    13261 cccaatttgt cgccatgttt aactggagca acatggggaa attcatcgcc gtggggctga
    13321 ccgatatact tgaaagttca gggcttagcg gcatcccggc gtttgtcggt ctggcgttgc
    13381 tttcctcttt cttatgcatg tttattgcca gcggttccgc aatctggtcg attctggccc
    13441 ccattttcgt accaatgttt atgctacttg gctttcaccc ggcatttgcg caaatcctct
    13501 ttcgtattgc cgactcatcc gtattgcctt tagcgccggt atctcctttt gttccactgt
    13561 ttcttggatt cctgcaacgc tacaaaccag acgcaaaact gggtacttac tattcgttag
    13621 tcttgcccta tccgcttatc tttttggtgg tatggctgct gatgttgctg gcgtggtatc
    13681 ttgttggtct gccgataggt ccggggattt acccacgttt gtcttaagag agaacggatg
    13741 ctgagattac ttgaagaaaa aattgccacg ccactgggtc cactgtgggt gatttgcgat
    13801 gagcaatttc gcctgcgggc ggttgaatgg gaagagtaca gcgaacgcat ggtgcagctg
    13861 ctggacatcc attatcgcaa agaaggctat gagcgcattt ctgccaccaa cccaggcggt
    13921 ttaagcgaca agcttcgtga ttattttgcc ggtaatctta gcattattga tacgcttccc
    13981 actgccacag gggggacgcc atttcagcgc gaagtctgga aaactctacg cactatcccc
    14041 tgcgggcagg taatgcatta cggccaactg gctgaacaat tgggccgccc tggcgcggcg
    14101 cgtgccgttg gtgcggcaaa cggatcgaat cccatcagca tcgtcgtacc ttgccatcgg
    14161 gttattggcc gaaacggcac catgaccgga tatgcaggcg gagttcagcg aaaagagtgg
    14221 ttattgcgcc acgaaggtta tcttttgctg taaacattaa acaatttgtg ccagcttgtt
    14281 cacactttta tgtaaagtta cccttaacaa cttaagggtt ttcaaataga tagacatata
    14341 tttacatctg atatcggaat tctctgctgt taaggtttgc ttagacttac ttgctcccta
    14401 aaaagatgtt aaaattgaca aatatcaatt acggcttgag cagacctatg atcccggaaa
    14461 agcgaattat acggcgcatt cagtctggcg gttgtgctat ccattgccag gattgcagca
    14521 tcagccagct ttgcatcccg ttcacactca acgaacatga gcttgatcag cttgataata
    14581 tcattgagcg gaagaagcct attcagaaag gccagacgct gtttaaggct ggtgatgaac
    14641 ttaaatcgct ttatgccatc cgctccggta cgattaaaag ttataccatc actgagcaag
    14701 gcgacgagca aatcactggt ttccatttag ctggcgacct ggtgggattt gacgccatcg
    14761 gcagcggcca tcacccgagc ttcgctcagg cgctggaaac ctcgatggta tgtgaaatcc
    14821 cgttcgaaac gctggacgat ttgtccggta aaatgccgaa tctgcgtcag cagatgatgc
    14881 gtctgatgag cggtgaaatc aaaggcgatc aggacatgat cctgctgttg tcgaagaaaa
    14941 atgccgagga acgtctggct gcattcatct acaacctgtc ccgtcgtttt gcccaacgcg
    15001 gcttctcccc tcgtgaattc cgcctgacga tgactcgtgg cgatatcggt aactatctgg
    15061 gcctgacggt agaaaccatc agccgtctgc tgggtcgctt ccagaaaagc ggtatgctgg
    15121 cagtcaaagg taaatacatc accatcgaaa ataacgatgc gctggcccag cttgctggtc
    15181 atacgcgtaa tgttgcctga tttttccgca taactcacta tccttctgtc atatcattaa
    15241 atttttctga tttattgatc tggcagaagg ttcatcactg tttcattcac cagatatggg
    15301 ttaatctttt aattacaaac tgcgttgaca gttgttgtaa ggagaccctg tatggctatg
    15361 tatcagaaca tgctcgttgt tatcgatcct aaccaggacg accaaccagc attgcggcga
    15421 gctgtttatt tacatcaacg gattggtggc aaaattaaag cctttttgcc gatctatgac
    15481 ttctcatacg aaatgaccac cctgctctcc ccggacgaac gtacggctat gcgtcagggc
    15541 gtcatcagcc agcgtacagc ctggatccac gagcaggcaa aatattatct caatgctggc
    15601 gttcccattg aaattaaagt ggtctggcat aaccgtcctt tcgaagccat cattcaggaa
    15661 gtgatcagcg gcgggcacga tttggtgcta aaaatggcgc accaacatga ccgtctggaa
    15721 gcggtgattt ttacgccaac ggactggcat ctgttacgca aatgcccaag cccggtgtgg
    15781 atggtgaaag accagccgtg gccggaagga ggcaaggcgc tggtggcggt gaatctcgcc
    15841 agtgaagagc cgtatcataa tgcgctcaat gaaaaactgg tcaaagagac gatcgaactg
    15901 gcagaacaag tcaaccatac cgaagttcat ctggttggcg cttatccggt aacgccaatt
    15961 aatatcgcga ttgaactgcc ggaatttgat ccgagcgttt ataacgatgc cattcgtggg
    16021 caacatttgc tggcaatgaa agctctgcgg cagaaattcg gcattaatga aaacatgacg
    16081 cacgtagaaa aaggtctgcc agaagaggtg attcctgatt tggcggaaca cttacaggcg
    16141 gggattgtgg ttctgggcac ggtaggacgc accggtattt cagcagcatt cctcggcaac
    16201 acggcggaac aggtgattga tcatcttcgc tgcgatctgt tggtcattaa acctgaccag
    16261 tatcagacac ccgttgaact ggatgacgaa gaagacgatt aacgactctt caataactga
    16321 caaggcccga gttatcgggc ctatttttta cttactgctc ttcgccgcca aggaaataaa
    16381 ttcccaacgg gattgccagc aacacagtaa agaccaggct ataaacaaaa atcatcgatg
    16441 actgaatcac atacattgat gtcgtccact cagacagcgg aatattgtac tgttctataa
    16501 cgccgccgat agtcgcgcga gtcacaaccg acgccgcaat aatgaaaacc gccaacaaac
    16561 caaagagaaa tttcttccct ttcgctgact tcagtttcgc cataatcatg atgtaatcct
    16621 tgtgcagaca aatttcttgt tacctaaacg taacaatacc atgacatttc accgttgtct
    16681 gctctgaaaa cctcacctct tagctggatt tacaatcaac gcattgatta gttagctaat
    16741 gttgctactt ccttccctga ctattgatga tctgaatgaa ttgtcgcggt aaaatagccc
    16801 cgccaggggt ttccggcatg acgacaatta tctggaggag cctgataaaa caatgatcgc
    16861 tgaactgttt acaaataatg cgcttaatct ggtcattatt ttcggtagct gcgcagcatt
    16921 gattctgatg agcttttggt ttcgccgcgg aaatcgtaaa agaaaaggtt ttttattcca
    16981 tgcggtgcaa tttttaatct acaccataat t
//
LOCUS       DAPGUL010000099        16866 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.101, whole genome shotgun sequence.
ACCESSION   DAPGUL010000099 DAPGUL010000000
VERSION     DAPGUL010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16866
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.101"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..83
                     /locus_tag="RHX21_003444"
     CDS             <1..83
                     /locus_tag="RHX21_003444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HDV1988588.1"
                     /translation="ITFKRLELIDRINDIIARHFPSVLSA"
     gene            complement(364..900)
                     /gene="yghD"
                     /locus_tag="RHX21_003445"
     CDS             complement(364..900)
                     /gene="yghD"
                     /locus_tag="RHX21_003445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GspM family type II secretion system protein
                     YghD"
                     /protein_id="HDV1988589.1"
                     /translation="MLRDKFIHYFQQWRERQLSRGEHWLAQHLAGRSPREKGMLLAAV
                     VFLFSVGYYVLIWQPLSERIEQQETMLQQLVAMNTRLRSAAPDIMAARKSATTTPAQV
                     SRVISDSASAHSVVIKRIAERGENIQVWIDPVVFNDLLNWLNALDEKYALRVTQIDAS
                     AAEKTGMVNVQRLEFGRG"
     gene            complement(902..2080)
                     /gene="gspL"
                     /locus_tag="RHX21_003446"
     CDS             complement(902..2080)
                     /gene="gspL"
                     /locus_tag="RHX21_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000097227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspL"
                     /protein_id="HDV1988590.1"
                     /translation="MSSILEIFFPLCASDTVRWQRRTPDVEHGIWPDVADEQLQQWLQ
                     TDAIRLYIPGEWISVWQVELPDVARKQIPTILPALLEEELNQDIDELHFAPLKIDQQL
                     ATVAVIHQQHMRNIAQWLQENGITRATVAPDWMSIPCGFMAGDAQRVICRIDECRGWS
                     AGLALAPVMFRAQLNEQDLPLSLTVVGIAPEKLSAWAGADAERLTVTALPAVTTYGEP
                     EGNLLTGPWQPRVSYRKQWARWRVMILPILLILVALAVERGVTLWSVSEQVAQSRTQA
                     EEQFLTLFPEQKRIVNLRSQVTMALKKYRPQADDTRLLAELSAIASTLKSASLSDIEM
                     RGFTFDQKRQTLHLQLRAANFASFDKLRSALATDYVVQQDALQKEGDAVSGGVTLRRK
                     "
     gene            complement(2077..3054)
                     /gene="gspK"
                     /locus_tag="RHX21_003447"
     CDS             complement(2077..3054)
                     /gene="gspK"
                     /locus_tag="RHX21_003447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001554494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspK"
                     /protein_id="HDV1988591.1"
                     /translation="MITSPPKRGMALVVVLVLLAVMMLVTITLSGRMQQQLGRTRSQQ
                     EYQQALWYSASAESLALSALSLSLKNEKRVHLTQPWASGPRFFPLPQGQIAVTLRDAQ
                     ACFNLNALAQPTTASRPLAVQQLIALISRLDVPAYRAELIAESLWEFIDEDRSVQTRL
                     GREDSEYLARSVPFYAANQPLADISEMRVVQGMDDGLYQKLKPLVCALPMTRQQININ
                     TLDVTQSVLLEALFDPWLSPVQARALLQQRPAKGWEDVDQFLAQPLLADVDERTKKQL
                     KTVLSVDSNYFWLRSDITVNEIELTMNSLIVRMGPQHFSVLWHQTGESE"
     gene            complement(3051..3656)
                     /gene="gspJ"
                     /locus_tag="RHX21_003448"
     CDS             complement(3051..3656)
                     /gene="gspJ"
                     /locus_tag="RHX21_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001255030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspJ"
                     /protein_id="HDV1988592.1"
                     /translation="MRRTRAGFTLLEMLVAIAIFASLALMAQQVTNGVTRVNNAVAGH
                     DQKLNLMQQTMSFLTHDLTQMMPRPVRGEQGQREPALLAGAGVLASESEGMRFVRGGV
                     VNPLMRLPRSNLLTVGYRIHDGYLERLAWPLTDAAGSVKPTMQKLIPADSLRLQFYDG
                     TRWQESWSSVQAIPVAVRMTLHSPQWGEIERIWLLRGPQLS"
     gene            complement(3653..4024)
                     /gene="gspI"
                     /locus_tag="RHX21_003449"
     CDS             complement(3653..4024)
                     /gene="gspI"
                     /locus_tag="RHX21_003449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001709020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspI"
                     /protein_id="HDV1988593.1"
                     /translation="MKRGFTLLEVMLALAIFALAATAVLQIASGALSNQQILEEKTVA
                     GWVAENQTALLYLMTREQRAVRQQGESDMAGSRWYWRTTPLSTGNALLQAVDIEVSLH
                     EDFSSVIQSRRAWFSAVGGQQ"
     gene            complement(4021..4584)
                     /gene="gspH"
                     /locus_tag="RHX21_003450"
     CDS             complement(4021..4584)
                     /gene="gspH"
                     /locus_tag="RHX21_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001394829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system minor pseudopilin GspH"
                     /protein_id="HDV1988594.1"
                     /translation="MPERGFTLLEIMLVIFLIGLASAGVVQTFATDSESPAKKAAQDF
                     LTRFAQFKDRAVIEGKTLGVLIDPPGYQFMQRRQGQWSPVSSTRLSAQVTVPKQVQML
                     LQPGSDIWQKEYALELQRRRLTLHDIELELQKEAKKKTPQIRFSPFEPAAPFTLRFYS
                     AAQNACWAVKLAHDGALSLNQCDERMP"
     gene            complement(4588..5043)
                     /gene="gspG"
                     /locus_tag="RHX21_003451"
     CDS             complement(4588..5043)
                     /gene="gspG"
                     /locus_tag="RHX21_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003912123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system major pseudopilin GspG"
                     /protein_id="HDV1988595.1"
                     /translation="MNSLSRTQKPRAGFTLLEVMVVIVILGVLASLVVPNLLGNKEKA
                     DRQKAISDIVALENALDMYRLDNGRYPTTEQGLEALIQQPANMADSRNYRTGGYIKRL
                     PKDPWGNDYQYLSPGEKGLFDVYTLGADGQENGEGAGADIGNWNLQEFQ"
     gene            complement(5060..6283)
                     /gene="gspF"
                     /locus_tag="RHX21_003452"
     CDS             complement(5060..6283)
                     /gene="gspF"
                     /locus_tag="RHX21_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system inner membrane protein
                     GspF"
                     /protein_id="HDV1988596.1"
                     /translation="MALFYYQALERNGRKTKGMIEADSARHARQLLRGKELIPVHIEA
                     RMNTSSGGMLQRRRHAHRRVAAADLALFTRQLATLVQAAMPLETCLQAVSEQSEKLHV
                     KSLGMALRSRIQEGYTLSDSLREHPRVFDSLFCSMVAAGEKSGHLDVVLNRLADYTEQ
                     RQRLKSRLLQAMLYPLVLLVVATGVVTILLTAVVPKIIEQFDHLGHALPASTRTLIAM
                     SDALQASGVYWLAGLLALLVLGQRLLKNPTMRLRWDKTVLRLPVTGRVARGLNTARFS
                     RTLSILTASSVPLLEGIQTAAAVSANRYVEQQLLLAADRVREGSSLRAALAELRLFPP
                     MMLYMIASGEQSGELETMLEQAAVNQEREFDTQVGLALGLFEPALVVMMAGVVLFIVI
                     AILEPMLQLNNMVGM"
     gene            complement(6283..7776)
                     /gene="gspE"
                     /locus_tag="RHX21_003453"
     CDS             complement(6283..7776)
                     /gene="gspE"
                     /locus_tag="RHX21_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001525635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system ATPase GspE"
                     /protein_id="HDV1988597.1"
                     /translation="MVPVAQETTANTVRLPYSFSRRFSLVAWCEASLEILHVHPLSLS
                     VLQELQRGLNAPFTLRQIDGAEFEQRLNAVWQRDSSEARQLMEDLGSAEDFFTLAEEL
                     PETEDLLESDDDAPIIKLINAMLAEAIKEGASDIHIETFEKSLVIRFRVDGTLHEMLR
                     PGRKLASLLVSRIKVMARLDIAEKRVPQDGRIALLLGGRAIDVRVSTMPSAWGERVVL
                     RLLDKNQARLTLERLGLSQQLTAQLRQLLHKPHGIFLVTGPTGSGKSTTLYAGLQELN
                     NHSRNILTVEDPIEYMIEGIGQTQVNTRVGMTFARGLRAILRQDPDVVMVGEIRDTET
                     AEIAVQASLTGHLVLSTLHTNTAVGAITRLQDMGVEPFLLSSSLTGVMAQRLVRTLCP
                     DCRQPAPATDEEKRLLGITDARTVTLYHPQGCPACNHKGFRGRTAIHELIVVDATLRD
                     LIHRQAGELELERYVRQHSAGIRSNGIEKVLAGETSLDEVLRVTMEA"
     gene            complement(7776..9836)
                     /gene="gspD"
                     /locus_tag="RHX21_003454"
     CDS             complement(7776..9836)
                     /gene="gspD"
                     /locus_tag="RHX21_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020234996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system secretin GspD"
                     /protein_id="HDV1988598.1"
                     /translation="MFWRDITLSVWRKKTTGLKTKKRLLPLVLAAALCSSPVWAEEAT
                     FTANFKDTDLKSFIETVGANLNKTIIMGPGVQGKVSIRTMTPLNERQYYQLFLNLLEA
                     QGYAVVPMENDVLKVVKSSAAKVEPLPLVGEGSDNYAGDEMVTKVVPVRNVSVRELAP
                     ILRQMIDSAGSGNVVNYDPSNVIMLTGRASVVERLTEVIQRVDHAGNRTEEVIPLDNA
                     SASEIARVLESLTKNSGENQPATLKSQIVADERTNSVIVSGDPATRDKMRRLIRRLDS
                     EMERSGNSQVFYLKYSKAEDLVDVLKQVSGTLTAAKEEAEGTVGSGREIVSIAASKHS
                     NALIVTAPQDIMQSLQSVIEQLDIRRAQVHVEALIVEVAEGSNINFGVQWASKDAGLM
                     QFANGTQIPIGTLGAAISQAKPQKGSTVISENGATTINPDTNGDLSTLAQLLSGFSGT
                     AVGVVKGDWMALVQAVKNDSSSNVLSTPSITTLDNQEAFFMVGQDVPVLTGSTVGSNN
                     SNPFNTVERKKVGIMLKVTPQINEGNAVQMVIEQEVSKVEGQTSLDVVFGERKLKTTV
                     LANDGELIVLGGLMDDQAGESVAKVPLLGDIPLIGNLFKSTADKKEKRNLMVFIRPTI
                     LRDGMAADGVSQRKYNYMRAEQIYRDEQGLSLMPHTAQPVLPAQNQALPPEVRAFLNA
                     GRTR"
     gene            complement(9866..10825)
                     /gene="gspC"
                     /locus_tag="RHX21_003455"
     CDS             complement(9866..10825)
                     /gene="gspC"
                     /locus_tag="RHX21_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspC"
                     /protein_id="HDV1988599.1"
                     /translation="MARVVFRDARIYLIQWLTKIRHTLNQRQSLNTDKEHLRKIVRGM
                     FWLMLLIISAKVAHSLWRYFSFSAEYTAVSPSANKPPRADAKTFDKNDVQLISQQNWF
                     GKYQPVATPVKQPEPVPVAETRLNVVLRGIAFGARPGAVIEEGGKQQVYLQGETLGSH
                     NAVIEEINRDHVMLRYQGKIERLSLAEEERSTVAVTNKKAVSDEAKQAVAEPAASAPV
                     EIPTAVRQALAKDPQKIFNYIQLTPVRKEGIVGYAVKPGADRSLFDASGFKEGDIAIA
                     LNQQDFTDPRAMIALMRQLPSMDSIQLTVLRKGARHDISIALR"
     gene            complement(10843..11253)
                     /gene="gspS2"
                     /locus_tag="RHX21_003456"
     CDS             complement(10843..11253)
                     /gene="gspS2"
                     /locus_tag="RHX21_003456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system pilot lipoprotein
                     GspS-beta"
                     /protein_id="HDV1988600.1"
                     /translation="MSIKQMPGRVLISLLLSVTGLLSGCASHNENASLLAKKQAQNIS
                     QNLPIKSAGYTLVLAQSSGTTVKMTIISEAGTQTTQTPDAFLISYQRQMCADPTVKLM
                     LTEGINYSITINDTRTGNQYQRKLDRTTCGIVKA"
     gene            complement(11319..12128)
                     /gene="pppA"
                     /locus_tag="RHX21_003457"
     CDS             complement(11319..12128)
                     /gene="pppA"
                     /locus_tag="RHX21_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417446.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase PppA"
                     /protein_id="HDV1988601.1"
                     /translation="MLFDVFQQYPAAMPILATVGGLIIGSFLNVVIWRYPIMLRQQMA
                     EFHGEMPSAQSKISLALPRSHCPHCQQTIRIRDNIPLLSWLMLKGRCRDCQAKISKRY
                     PLVELLTALAFLLASLVWPESGWALAVMILSAWLIAASVIDLDHQWLPDVFTQGVLWT
                     GLIAAWAQQSPLTLQDAVTGVLVGFITFYSLRWIAGIVLRKEALGMGDVLLFAALGSW
                     VGPLSLPNVALIASCCGLIYAVIIKKGSTTLPFGPCLSLGGIATLYLQALF"
     gene            complement(12268..16836)
                     /gene="sslE"
                     /locus_tag="RHX21_003458"
     CDS             complement(12268..16836)
                     /gene="sslE"
                     /locus_tag="RHX21_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein metalloprotease SslE"
                     /protein_id="HDV1988602.1"
                     /translation="MNKKFKYKKSLLAAILSATLLAGCDGGGSGSSSDTPPVDSGTGS
                     LPEVKPDPTPNPEPTPEPTPDPEPTPEPTPDPEPTPEPEPEPVPTKTGYLTLGGSLRV
                     TGDITCNDESSDGFTFTPGDKVTCVAGNNTTIATFDTQSEAARSLRAVEKVSFSLEDA
                     QELAGSDNKKSNALSLVTSMNSCPANTEQVCLEFSSVIESKRFDSLYKQIDLAPEEFK
                     KLVNEEVENNAATDKAPSTHTSPVVPVTTPGTKPDLNASFVSANAEQFYQYQPSEIIL
                     SEGRLVDSQGYGVAGVNYYTNSGRGVTGENGEFSFSWGETISFGIDTFELGSVRGNKS
                     TIALTELGDEVRGANIDQLIHRYSTTGQNNTRVVPDDVRKVFAEYPNVINEIINLSLS
                     NGATLDEGEQVVNLPNAFIEQFKTGQAKEIDTAICAKTDGCNEARWFSLTTRNVNDGQ
                     IQGVINKLWGVDTNYKSVSKFHVFHDSTNFYGSTGNARGQAVVNISNAAFPILMARND
                     KNYWLAFGEKRAWDKNELAYITEAPSLVEPENVTRDTATFNLPFISLGQVGEGKLMVI
                     GNPHYNSILRCPNGYSWNGGVNKDGQCTLNSDPDDMKNFMENVLRYLSDDKWTPDAKA
                     SMTVGTNLDTVYFKRHGQVTGNSAAFDFHPDFAGISVEHLSSYGDLDPQEMPLLILNG
                     FEYVTQVGNDPYAIPLRADTSKPKLTQQDVTDLIAYLNKGGSVLIMENVMSNLKEESA
                     SGFVRLLDAAGLSMALNKSVVNNDPQGYPNRVRQQRATGIWVYERYPAVDGALPYTID
                     SKTGEVKWKYQVENKPDDKPKLEVASWLEDVDGKQETRYAFIDEADHKTEDSLKAAKE
                     KIFAAFPGLKECTNPAYHYEVNCLEYRPGTGVPVTGGMYVPQYTQLSLNADTAKAMVQ
                     AADLGTNIQRLYQHELYFRTNGRKGERLSSVDLERLYQNMSVWLWNDTSYRYEEGKND
                     ELGFKTFTEFLNCYANDAYAGGTKCSADLKKSLVDNNMIYGDGSSKAGMMNPSYPLNY
                     MEKPLTRLMLGRSWWDLNIKVDVEKYPGAVSEEGQNVTETISLYSNPTKWFAGNMQST
                     GLWAPAQKEVTIKSNANVPVTVTVALADDLTGREKHEVALNRPPRVTKTYSLDASGTV
                     KFKVPYGGLIYIKGNSSTNESASFTFTGVVKAPFYKDGAWKNDLNSPAPLGELESDAF
                     VYTTPKKNLNASNYTGGLEQFANDLDTFARSMNDFYGRDETSGKHRMFTYKALTGHKH
                     RFTNDVQISIGDAHSGYPVMNSSFSTNSTTLPTTPLNDWLIWHEVGHNAAETPLTVPG
                     ATEVANNVLALYMQDRYLGKMNRVADDITVAPEYLEESNNQAWARGGAGDRLLMYAQL
                     KEWAEKNFDIKKWYPDGTPLPEFYSEREGMKGWNLFQLMHRKARGDDVGDKTFGGKNY
                     CAESNGNAADTLMLCASWVAQTDLSEFFKKWNPGANAYQLPGASEMSFEGGVSQSAYN
                     TLASLNLPKPKQGPETINKVTEYSMPAE"
BASE COUNT         3733 a         4819 c         4252 g         4062 t
ORIGIN      
        1 acatcacttt caaaaggctg gagctgattg acagaattaa cgatataata gccaggcact
       61 ttccttctgt gctctcagcc tgaccccgag tttgattccc tttcgatatc aaaagggact
      121 gcgggtacaa aagagggtac atatttcacc aaaccaaaca aaataaaata atatcaacat
      181 gatagaagca ttcttcgatt ccgagtccgg caccactaat tcttaagaac ccgcccacaa
      241 ggcgggtttt tgcttttgga tctgacaata accttcacga aaaaagtttg cttataaagt
      301 ctgggggaat tactctcgcc acgttaacga gagtaatttt attgatacta atctcctgat
      361 actttacccc cgtccaaact ccagccgctg cacattcacc atcccagtct tctcagcagc
      421 actggcatca atttgtgtca cccgcagcgc atacttttca tccagcgcgt ttaaccagtt
      481 cagcaggtca ttaaacacca ccggatctat ccagacctga atattctccc cacgctcggc
      541 tatccgcttg atgactaccg agtgcgcgga agcgctgtca ctgataaccc gcgatacctg
      601 cgcaggcgtt gttgtggcgg attttcgcgc cgccataata tccggcgcgg cgctcctcag
      661 tctggtgttc atcgccacca gttgctgcaa cattgtctcc tgttgttcta tccgttcgct
      721 caacggctgc cagatgagga cgtaatatcc gacgctaaac aggaacacca ccgctgccag
      781 taacatgccc ttttcacgcg gagaacgccc cgccaggtgt tgtgccagcc agtgttcgcc
      841 acggcttaac tggcgttcac gccattgctg aaaatagtga ataaatttat cgcgtaacat
      901 gttatttcct ccgcaacgtt acgccgccgg aaaccgcatc accctctttc tgtaatgcgt
      961 cctgttgcac aacataatcg gttgccagtg cactacgcag tttgtcgaaa ctggcaaagt
     1021 tagcagcccg caactggagg tgaagcgtct ggcgtttttg atcaaaggtg aaaccacgca
     1081 tttcgatgtc ggaaagtgac gctgatttca gggtgctggc tatcgctgac aactcggcga
     1141 gcagccgggt atcgtcggcc tgtgggcgat attttttcag cgccatcgtc acctgagagc
     1201 gtaaattcac aatccgcttc tgctccggga acaacgttaa gaactgttcc tccgcctggg
     1261 tgcggctttg cgccacctgt tcgctgacgc tccataacgt cacgccccgc tccactgcca
     1321 gcgcaaccag aatcagcaat atcggcagaa tcatcacccg ccagcgcgcc cactgttttc
     1381 ggtagctgac gcgaggctgc cacggccctg tcagcaggtt cccttccggt tcgccataag
     1441 tggtaacggc gggcagagct gtaacggtca ggcgttcagc gtctgcgcca gcccatgctg
     1501 atagcttttc cggtgcaatg ccgactacgg ttagcgaaag cggtaaatcc tgctcattga
     1561 gctgggcgcg gaacatgacc ggagccagcg ccagcccggc gctccatccc cggcattcat
     1621 cgatgcggca gataacccgt tgcgcatcgc cagccataaa cccacaagga atggacatcc
     1681 agtccggcgc gacggtagcg cgggtgatgc cgttttcctg caaccactgc gcaatgttgc
     1741 gcatatgctg ttggtgaatc actgctacgg ttgccagttg ctggtcgatt ttcaacgggg
     1801 cgaaatgcag ttcatcgata tcctggttca gctcttcttc cagcaaggcg ggcagaatag
     1861 tcggtatctg cttgcgggcg acatcaggca gttcaacctg ccagacgctg atccattcgc
     1921 cgggaatgta gagtcgaatc gcatcggttt gcagccattg ctgaagctgt tcgtcagcaa
     1981 cgtcaggcca gataccgtgt tccacgtcgg gtgtacggcg ctgccagcgg acggtatcgg
     2041 aggcgcaaag cgggaaaaaa atctcaagga tggaactcac tcactttctc ctgtctgatg
     2101 ccagagaacc gaaaagtgtt gtgggcccat gcggacaatt aacgaattca tcgtcagttc
     2161 aatctcattc acggtgatat ctgaacgcag ccagaagtaa ttgctgtcca cgctcaggac
     2221 ggtttttagc tgttttttag tacgctcatc gacgtcagca agtagcggct gtgcaagaaa
     2281 ctgatcgaca tcttcccagc ccttcgccgg acgttgttgt aataatgccc gcgcctgaac
     2341 agggcttaac cacgggtcaa acagcgcctc aagaagcaca ctttgcgtga cgtctaaggt
     2401 attgatgttg atttgctggc gggtcatcgg cagcgcacag accagcggtt tcagtttttg
     2461 ataaagcccg tcgtccattc cctgcaccac gcgcatctcg ctgatatcgg ccagcggttg
     2521 attcgcggcg tagaaaggca ccgaacgggc gagatactcg ctgtcttcac ggcccagacg
     2581 tgtctggacg ctgcggtcct cgtcaataaa ctcccacagg ctttcggcta tcagttcggc
     2641 ccgataagca ggcacatcca ggcgcgagat cagggcaatc aactgttgta ccgcaagcgg
     2701 acgcgacgcc gttgtcggct gagcaagggc attcaggtta aagcaagcct gtgcgtcacg
     2761 cagggtgacc gcaatttgcc cctgcggcag agggaagaaa cgagggccgg atgcccacgg
     2821 ctgtgtcaga tgcacgcgct tttcattttt caggctcaga ctgagcgcgc tcagcgccag
     2881 gctttccgca ctggcgctgt accacagcgc ctgctggtac tcctgctggc tgcgcgttcg
     2941 cccaagttgt tgctgcatcc gcccggaaag cgtgatggtt accagcatca taaccgccag
     3001 caataccagc accacgacca gtgccattcc gcgttttggt ggtgaggtga tcatgataat
     3061 tgcggcccgc gtaacaacca gatgcgttca atctcgcccc attgcggcga atgcagagtc
     3121 atgcgcactg ccacagggat cgcctgtact gacgaccagc tctcctgcca gcgcgtacca
     3181 tcatagaact gcaaacggag cgaatccgcc ggaatcaact tttgcattgt cggcttcacg
     3241 ctgcctgcgg catcggtcag cggccaggct aaccgttcga gataaccgtc atgaatgcgg
     3301 taaccgacgg tgagcagatt gctgcgtggc agacgcatca acgggttaac cacgccgccg
     3361 cgcacaaagc gcatgccttc actctcagac gccagcacgc cagcgcccgc cagtaacgct
     3421 ggttcacgct ggccctgttc gcctcttacc ggacgcggca tcatttgggt cagatcgtgg
     3481 gtcagaaaac tcatcgtttg ctgcatgagg tttagttttt gatcatgtcc ggcgacggcg
     3541 ttattcacgc gtgtgacacc gtttgtcacc tgctgcgcca tcagtgccag cgaggcaaaa
     3601 atggcaattg ccaccaacat ttccagtaac gtgaaaccag cgcgagtcct tctcactgtt
     3661 ggcctcccac ggcgctaaac caggcgcgtc gtgactgaat caccgacgaa aagtcttcgt
     3721 gaaggctgac ttcaatatcc accgcctgga gcagcgcgtt gcctgtactc agcggtgtgg
     3781 ttcgccagta ccagcggctt cctgccatat cgctctcgcc ctgctgcctg accgcccgct
     3841 gctcgcgggt catcaggtag agcagcgcgg tctggttttc agccacccag cccgctaccg
     3901 ttttttcctc aagaatttgc tgattactca gcgcaccgct ggcaatctgt aacaccgccg
     3961 tggcagccag cgcaaaaatc gccagcgcga gcatcacttc cagcaaggta aatccgcgct
     4021 tcatggcatc ctctcatcac attgattgag ggataacgcg ccatcgtgcg ccagttttac
     4081 cgcccaacat gcgttttgcg ccgccgagta gaagcgcagc gtaaacggcg cggcgggttc
     4141 aaaaggcgaa aaacggatct gcggagtctt ctttttcgcc tctttttgca gctccagttc
     4201 aatatcgtgc agcgtcagtc gacgacgttg cagctccagc gcatattcct tctgccagat
     4261 atcacttccg ggttgtaaca gcatctgcac ctgtttcggc accgtaacct gtgcagataa
     4321 ccgggtcgag gaaacgggcg accactgccc ctgacgacgc tgcataaact ggtagccagg
     4381 cgggtcgatt agcacaccga gtgttttccc ttcgatcact gccctgtcct taaactgcgc
     4441 aaagcgagtc agaaaatcct gcgccgcttt tttcgcgggc gattcagaat cggtcgcaaa
     4501 agtctgtacc acgcccgcac tggcaaggcc gataagaaaa atcaccagca tgatttccag
     4561 aagtgtgaat ccgcgttcag gcactgctta ctgaaactcc tgcaaattcc agttaccgat
     4621 atctgcgcca gcgccttccc cgttttcctg accatccgcc cccagggtat aaacatcaaa
     4681 cagccctttt tcacccggac tgagatactg ataatcattg ccccacggat cctttggcag
     4741 tcgtttaatg tatccaccag tacggtagtt gcgggagtcc gccatattgg ctggctgctg
     4801 gatcagcgcc tcaagcccct gttctgtggt cggataacgc ccgttatcca gtcggtacat
     4861 atccagtgcg ttttccagcg ccacgatatc gctgatggct ttttgccgat cggctttctc
     4921 tttgttgccc aacaggttag gcaccaccag acttgccagg acgccaagaa taacaatcac
     4981 caccatcact tccagcaggg taaaacctgc ccgtggtttt tgtgtgcggg ataacgaatt
     5041 catgtgataa ctccgtaaat tacattccaa ccatattatt cagttgcagc atcggctcga
     5101 ggatggcgat gacaataaac agcaccacgc ccgccatcat caccaccagc gcaggctcaa
     5161 acagccccaa cgccagcccc acctgggtat caaattcccg ttcctggtta acagcggcct
     5221 gctcaagcat ggtttccagt tcgccgctct gttcgccgga ggcgatcatg tacagcatca
     5281 tcggggggaa caggcgcaac tccgccagcg cggcgcgcag actgcttcct tcgcggacgc
     5341 gatctgccgc cagcagtagt tgttgttcga catagcgatt tgccgacaca gcggcagcgg
     5401 tctgaatacc ttccagtagc ggaacactgc tggcggtgag gatgcttaag gtgcgggaaa
     5461 aacgcgccgt attcagcccg cgcgcaacac gccctgtcac gggcagacgc agcacggttt
     5521 tatcccagcg caggcgcata gtaggatttt taagtagccg ttgccccagc accagaagcg
     5581 ccagcaatcc cgccagccag taaacgccgc tggcctgtaa cgcgtcgctc atggcaataa
     5641 gcgtgcgggt tgaggcgggt agcgcgtgtc cgagatgatc aaactgttcg atgattttcg
     5701 gcaccactgc cgtcagcaaa atagtgacta cgcccgttgc caccaccagc agaaccagcg
     5761 gatagagcat ggcctgcaat agacgtgatt tcaggcgctg tcgctgttcg gtgtaatctg
     5821 ccaggcgatt aagcaccacg tcgagatgcc cggatttttc tccggcagca accatcgaac
     5881 aaaacagaga atcaaagacg cggggatgtt cgcgcaggct gtccgacagg gtgtaacctt
     5941 cctgaatccg gctgcgcagc gccattccga ggctttttac atgcagtttt tcactttgct
     6001 cactgaccgc ctgtaagcag gtttccagcg gcattgctgc ctgtaccagc gttgccagtt
     6061 ggcgcgtgaa cagcgcaaga tctgccgccg ccacgcgacg atgtgcgtgc cgccgacgct
     6121 gcaacatccc ccctgacgaa gtattcatcc gggcttcaat atgcacgggg ataagctctt
     6181 taccgcgcaa caactggcgg gcatgacgcg cggaatccgc ctcaatcata cctttggttt
     6241 tgcgaccatt acgctccagc gcctgatagt aaaacagtgc cattacgcct ccatggttac
     6301 ccgcagaact tcatcgagag aggtttctcc ggcgagcact ttctcaatgc cgttgctgcg
     6361 gatacccgca gagtgttgtc ggacataacg ttccagctcc agctccccgg cctgacggtg
     6421 gatcaaatca cgcaatgtgg catccaccac gatcagctca tggatggcag tccgtccgcg
     6481 aaaacctttg tgattacagg cgggacagcc ctgtggatgg tacagagtga cggtacgggc
     6541 gtcggtaatt cccagcaggc gtttttcttc gtcagtggct ggtgcgggct ggcggcagtc
     6601 gggacacagc gtgcgaacca gtcgctgcgc catcacgccc gtcagactgg aagagagcag
     6661 gaaaggctcc acgcccatat cctgcaaacg tgtgatcgcc cccaccgctg tgttggtatg
     6721 cagcgtggaa aggaccaggt gtccggtaag tgaagcctgg acggcgattt ctgcggtttc
     6781 ggtatcgcga atttcaccga ccatcaccac atccgggtcc tgacgcaaaa tcgcgcgcag
     6841 cccacgggca aaggtcatgc cgacgcgggt gttaacctgc gtctgaccga tcccttcaat
     6901 catgtattcg atgggatctt caaccgtgag aatgttgcgc gaatggttgt tcagctcctg
     6961 caatccggcg tacagcgtgg tgcttttgcc ggaacccgtc ggccccgtca ccagaaagat
     7021 gccgtgcggt ttgtgtaaca gctggcgcaa ctgcgcggtc agttgctggc taagccccag
     7081 acgctccagc gtcaggcggg cctggttttt gtccagcagt cgcagcacca cgcgctcgcc
     7141 ccaggcagaa ggcatggtgg agacacgcac gtcaatcgcc cggccgccca gcaacagcgc
     7201 aatacgtcca tcctgcggca cgcgcttttc ggcaatgtcc agccgcgcca tcaccttgat
     7261 acgcgacacc agcagcgagg ccagtttgcg ccccgggcgc agcatttcat gtaatgtgcc
     7321 gtcaacgcga aaacggatca ccagactctt ttcaaatgtc tcgatgtgga tatccgaagc
     7381 gccttcttta atcgcctctg ccagcatggc gttgatcagt ttgatgatcg gcgcatcgtc
     7441 gtcactttcc agcagatctt ccgtttctgg cagttcttcc gcgagagtaa aaaagtcctc
     7501 agcagaaccg agatcttcca tcagctggcg agcctcggaa gagtcccgct gccagaccgc
     7561 attcagccgc tgttcaaatt cggccccgtc gatttgccgc agcgtaaagg gcgcgttcag
     7621 cccccgctgc agctcctgca aaacagagag cgacaacgga tgcacatgga ggatctccag
     7681 cgacgcttcg caccatgcca ccaggctaaa ccgacggctg aaactgtagg gcagacgcac
     7741 ggtgttagcg gtggtttcct gtgctacagg caccattaac gcgttctccc ggcattaagg
     7801 aatgcacgaa cttccggcgg tagagcctga ttttgcgctg gcagtaccgg ctgcgcggtg
     7861 tgcggcatca ggcttaaacc ttgctcatcg cgatagatct gctcggcgcg catgtagtta
     7921 tatttgcgct gcgacacgcc gtctgccgcc ataccgtcac gcagaatggt cggacggata
     7981 aacaccatca ggttacgttt ttctttttta tccgccgtcg atttaaacag gttaccaatc
     8041 aatgggatat cgcccagcag cggcactttc gccacgcttt ctcccgcctg atcgtccatc
     8101 agaccaccaa gcacaatcag ctcaccatcg ttagccagca cggtggtttt cagtttgcgc
     8161 tcaccaaaca ccacgtcgag gctggtctgt ccttccacct tcgagacttc ctgctcaatc
     8221 accatctgta ccgcgttacc ttcgttaatc tgcggcgtga ctttcagcat gatgccgact
     8281 tttttccttt ctactgtatt gaaaggattg ctgttattgg agccaacggt agagccggtt
     8341 aataccggaa cgtcctggcc caccatgaag aaggcttcct ggttgtccag cgtagtgatg
     8401 ctcggcgtgg agagaacgtt cgagctggag tcgtttttaa ccgcctgcac cagtgccatc
     8461 cagtcgcctt tcaccacgcc aaccgccgta ccgctaaatc cagaaagaag ctgggcgagt
     8521 gtggagagat cgccgttggt atccggatta atggtggtag cgccgttttc actgatcacc
     8581 gtcgagcctt tctgcggttt cgcctgagaa atggctgccc ccagcgtacc gatagggatc
     8641 tgcgtaccat tagcaaactg cattaatccg gcatctttcg acgcccactg cacgccgaag
     8701 ttgatattgc taccttcggc aacttccacg atcaacgcct cgacgtgcac ctgagcacgg
     8761 cgaatatcca gttgttcaat cacgctttgc agcgactgca tgatgtcctg cggtgcggtt
     8821 acaatcaggg cattactgtg tttgctggcg gcgatggata caatctcacg cccgctaccg
     8881 accgtgcctt ccgcctcttc tttagccgcc gtgagcgtgc cgctgacctg cttcagcaca
     8941 tcgaccagat cttcggcttt gctgtatttg agatagaaca cctggctgtt gccgctgcgt
     9001 tccatttctg agtccagccg acggatcagg cggcgcattt tgtcccgcgt ggccgggtca
     9061 ccactgacaa tcacactgtt ggtgcgttcg tcggcgacaa tttgagattt cagcgtcgca
     9121 ggctggttct cgccgctgtt tttcgtcagg ctttccagca cgcgggcgat ttccgaagcc
     9181 gaggcgttat ccagcgggat cacctcttcg gtgcgattac ccgcgtgatc cacgcgctgg
     9241 atcacttctg tcaggcgctc cacaacggag gcgcgtccgg tgagcataat cacgttggag
     9301 ggatcgtaat taacaacatt gcctgagcct gcgctgtcga tcatctggcg cagaatcggt
     9361 gccagctcgc gtaccgacac attacgtacc ggcactactt tggtgaccat ttcatcgccc
     9421 gcgtagttgt cgctgccttc accgaccagc ggcagcggct cgactttcgc agcgctggat
     9481 ttcaccacct tcagcacgtc gttttccatc ggtacgacgg catacccctg tgcttccagc
     9541 aggttaagga atagctggta atactggcgt tcattgagcg gggtcatggt gcgaatactc
     9601 actttcccct gtacgcccgg ccccataatg atggttttat taaggttagc gccgacggtt
     9661 tcgatgaacg atttcaggtc ggtatcttta aaattagcgg tgaaagtggc ttcttccgcc
     9721 cagaccggtg aactgcataa tgccgctgcc agcaccagcg gcagtaaacg cttttttgtt
     9781 ttgaggccag ttgtcttctt acgccagacc gacaacgtaa tatcacgcca aaacacgatg
     9841 aatgattctc ctggattaaa tgcggttagc gcagcgcgat ggaaatgtcg tggcgcgcac
     9901 ccttgcgtaa aaccgtaagt tgaatggaat ccattgaagg taactgccgc atcagagcaa
     9961 tcattgctcg tggatcagtg aaatcctgct gatttagcgc aatggcgata tcgccttcct
    10021 tgaaaccgct ggcatcgaac agagaacgat ctgcccccgg cttcactgca taaccgacaa
    10081 tcccctcctt acgcacaggc gtaagctgga tatagttaaa aattttctgc ggatctttcg
    10141 ccagtgcctg acgcacggca gtcgggatct caactggcgc actggcagca ggctcagcaa
    10201 cagcttgctt tgcttcgtca ctgacagctt ttttgttggt cacggcaaca gtggaacgct
    10261 cctcttcagc caggctcagg cgctctattt ttccctgata gcgcagcatc acatggtcgc
    10321 gattgatttc ctcaatcacc gcattgtgcg agccaagcgt ttcaccctgc aaatagacct
    10381 gctgtttacc gccttcttca ataaccgcgc cgggtctggc accaaaggca atcccgcgca
    10441 gcaccacatt aagacgcgtt tctgccacag gcacaggttc gggttgtttt accggcgtgg
    10501 cgacgggctg atatttgcca aaccagtttt gctggctgat taattgcacg tcatttttat
    10561 cgaacgtttt tgcatccgca cggggcggtt tattcgccga tggggaaaca gccgtatatt
    10621 ccgcagaaaa ggagaaatag cgccagagtg aatgcgccac ttttgcagaa ataataagca
    10681 gcatcagcca gaacatcccg cgtacaattt ttcgcagatg ctctttgtct gtattaagag
    10741 attgtctctg gttaagagtg tgacgaattt ttgtcagcca ttgaatgaga taaattcgtg
    10801 cgtcacgaaa aacaacccgc gccaatttat atctacccga cgttatgctt tgactattcc
    10861 acaggtggta cgatccagtt tccgctgata ctggttacct gtacgtgtat cattaatcgt
    10921 tatgctgtaa ttaattccct cagtgagcat taatttcact gttgggtcag cgcacatttg
    10981 tcgttgatag ctgattaaaa aggcgtctgg cgtctgcgtg gtctgagtac ccgcttcgct
    11041 gataatggtc atttttaccg tcgtgccgct actttgtgcc agcactaagg tatatcccgc
    11101 agatttaatc ggcaggtttt ggctgatatt ttgcgcctgt tttttcgcca gcaaactggc
    11161 gttttcatta tggctggcac agccacttaa taatcctgta acgctcaaca atagcgatat
    11221 taataccctc cctggcatct gttttatcga catggtaaat aatctctaag gttattaata
    11281 agagttaaaa tgtcactttg ataatgacgt ggttatcatt aaaacaatgc ctgtagataa
    11341 agtgttgcta taccgcccag acttaaacac ggtccaaaag gcagtgtggt tgatcctttt
    11401 tttataataa cggcatatat caggccgcag catgaggcga ttaaagcaac attgggcagt
    11461 gacaacggcc ccacccaact acctaacgca gcgaacaata atacatcgcc catgcctaat
    11521 gcttctttac gcagaactat tccggctatc cagcgcagag agtaaaaagt gataaacccc
    11581 accaggacgc cggtgactgc atcttgtagc gtgagcgggc tctgctgcgc ccatgccgca
    11641 attagtcccg tccacaatac gccctgagta aaaacatcgg gcagccattg gtgatcgagg
    11701 tcaatgacgc tcgcggcaat cagccaggcg gataatatca tcaccgccag cgcccatcca
    11761 ctttccggcc agaccagact cgccagcaaa aaagcgagtg ctgtcaataa ctccaccagc
    11821 ggataacgct tgctgatttt cgcctgacag tcgcggcagc gccctttgag catcagccag
    11881 gagagcagcg gaatattgtc acgtatccgg atggtctgct gacaatgtgg gcagtgcgaa
    11941 cgcggtagcg caaggcttat ttttgactgc gcactcggca tttcaccatg aaactccgcc
    12001 atttgttggc gcagcatgat ggggtaacgc caaatcacca cattcaaaaa actgccgata
    12061 atcaatcctc cgacggtagc cagtatgggc atcgccgcgg ggtattgctg aaaaacatca
    12121 aaaagcatgg ttaaaggttg tttgttgtaa cttgccggat gcgggcctgc aggtgtatgc
    12181 catatggctt tcctccaggc ccaataagct ggcgcaaccc ggtgcgcctt atttcatgcc
    12241 ggatgcggcg tgaacgcctt atccgggtta ttcagcaggc atcgaatact cggtaacctt
    12301 attaatggtt tccggccctt gcttcggttt cggcagattg agtgacgcca gcgtgttgta
    12361 cgccgactgg ctcacaccgc cctcgaagct catctcgctc gcccccggca gctggtaagc
    12421 attcgcaccc ggattccatt tcttaaagaa ctccgaaaga tccgtctgag cgacccagga
    12481 tgcacacagc atcagcgtgt cagcagcgtt accgttggat tcagcacagt aattcttgcc
    12541 accaaaggtc ttgtcaccaa cgtcatcgcc gcgcgcttta cggtgcatca actggaacag
    12601 gttccagcct ttcatccctt cacgctcgct gtaaaactct ggcagaggag tgccatctgg
    12661 ataccatttc ttgatatcaa agtttttctc tgcccattcc ttcagctgcg cgtacatcag
    12721 cagacggtca cccgcaccgc cgcgtgccca tgcctggttg ttgctctcct ccagatattc
    12781 cggtgcgacg gtaatatcgt cagcgacacg gttcatcttg ccgagatagc gatcctgcat
    12841 gtacagcgcc agcacgttgt tcgcgacttc agttgcaccc ggtacagtca gcggtgtttc
    12901 tgcggcgttg tgccctactt cgtgccagat caaccagtcg ttcagcggcg tcgtcggcag
    12961 cgtggtgctg ttcgtcgaga agctgctgtt cattaccgga taacccgagt gcgcatcacc
    13021 gatggagatc tgcacatcgt ttgtgaaacg atgtttatgt cccgtcaatg ctttataggt
    13081 aaacatccgg tgcttaccgc tcgtttcatc acgaccgtag aagtcattca tcgatctggc
    13141 aaaggtgtcc agatcgttag cgaattgctc cagtccgcca gtgtaattgc tggcattcag
    13201 gttcttcttc ggtgtggtat agacgaaagc gtctgattcc agctcaccca gcggagccgg
    13261 tgagttcaga tcgtttttcc atgcgccgtc tttatagaac ggtgctttta ccacgccagt
    13321 aaaggtgaag ctggcagatt cattggtaga gctattgccc ttgatataaa tcaggccacc
    13381 gtaaggcacc ttgaacttca ccgtaccgct agcgtccaga gagtacgttt tagtcactct
    13441 tggcggacgg ttcagcgcaa cttcatgctt ctcacgtccg gtcaggtcgt cagccagcgc
    13501 cacggtgacg gtcacaggaa cgttcgcatt ggacttaatg gtgacctctt tctgagccgg
    13561 tgcccacagg ccagttgact gcatgttacc tgcaaaccat ttggtcggat tcgagtacag
    13621 gctgatggtt tcagtaacgt tctgtccctc ttccgatact gctcccggat acttctcgac
    13681 atcaactttg atgttcagat cccaccagga acggcccagc atcaggcgtg tcagcggttt
    13741 ttccatatag ttgagcgggt agctcgggtt catcatgccc gctttgctgc taccgtcacc
    13801 gtagatcatg ttgttatcga ccagcgattt tttcagatct gcagaacact tggtgccgcc
    13861 tgcataggca tcattggcgt agcagttcag gaactcggtg aacgttttaa agcccagctc
    13921 gtcatttttg ccttcttcat aacgatagct cgtatcgttc cacagccaga ccgacatgtt
    13981 ctggtacaga cgttccagat cgacgctgct cagacgctca cctttgcgac cattggtccg
    14041 gaagtagagc tcatgctgat acagacgctg aatgttggtg cctaaatccg cagcctgcac
    14101 catcgctttt gcagtgtcgg cgttaaggct tagttgcgta tactgtggaa catacatgcc
    14161 accagtaacc ggaacccccg tgccaggacg atattccaga cagttgacct catagtgata
    14221 tgccggatta gtacactctt tcagccccgg gaacgcggcg aaaattttct ccttcgcagc
    14281 cttcagagaa tcctctgttt tatgatcggc ctcatcaata aaggcataac gcgtttcctg
    14341 tttgccatct acatcttcca gccagctggc aacttccagc ttcggtttgt catcaggttt
    14401 gttttctacc tgatatttcc acttaacttc ccctgtctta ctatcgatgg tgtacggcag
    14461 cgcaccatct acggcaggat aacgttcata gacccaaatg cccgttgcgc gctgctgacg
    14521 aacgcggttc ggataccctt gcggatcgtt atttactacc gacttgttca gtgccatcga
    14581 cagacctgcg gcatccaaca gacgcacaaa accagacgcg ctctcttcct taagattgct
    14641 catcacgttt tccatgatca gcaccgatcc acctttgttc agataggcga tcagatcggt
    14701 cacatcctgc tgagtcagct tcggtttgct ggtatctgca cgcagcggga ttgcataagg
    14761 atcgttaccc acctgagtca catattcaaa gccgttaagg atcagcagcg gcatttcctg
    14821 cggatcgaga tcgccatagc tacttaaatg ctcaacagag atgcccgcaa aatccggatg
    14881 gaagtcgaac gcagcgctgt ttcctgtaac ctgaccatga cgtttaaaat agacagtatc
    14941 caggttggtg cctacggtca tgctggcttt cgcgtccggc gtccatttat cgtcggacag
    15001 atagcgcagc acgttctcca tgaagttctt catgtcatcc gggtcgctgt tgagcgtaca
    15061 ctgcccatct ttattaacgc ccccgttcca gctgtaaccg ttcgggcaac gcaaaatgct
    15121 gttgtagtgt gggttaccga taaccatcag tttgccctca ccgacttgcc ccagcgaaat
    15181 aaacggcagg ttgaaagtgg cggtatcgcg cgtaacgttt tccggctcaa caagagaagg
    15241 cgcttccgta atgtacgcca gctcattttt atcccaggcg cgtttttcgc caaacgccag
    15301 ccagtagttt ttatcattac gcgccatcag aatcgggaag gccgcgttgg agatattcac
    15361 caccgcctga ccgcgcgcat tacccgtgct gccatagaag ttggtagagt catggaatac
    15421 atggaacttg ctgacagatt tgtagttcgt atccacgccc cacagcttgt tgataacgcc
    15481 ctgaatctgg ccgtcattaa cattgcgcgt cgtcagcgag aaccagcgag cctcgttaca
    15541 accgtcggtt ttcgcacaaa tcgcggtatc gatctctttg gcctgacccg tcttaaactg
    15601 ctcgataaat gcgtttggca gattaacaac ttgctcacct tcatccagcg tcgcaccgtt
    15661 ggataacgag agattgataa tctcgttgat cacgttggga tattcggcaa agaccttgcg
    15721 tacatcatcc ggaacaacac gggtattatt ttgcccggtc gtcgaatagc gatgaataag
    15781 ctgatcgata ttcgccccgc gaacttcatc acccagttca gtcagcgcaa tggtcgactt
    15841 attgccgcgc actgaaccca gttcaaaggt atcgatacca aaggagatgg tttcgcccca
    15901 gctaaaagaa aattcaccat tttcccctgt cacgccacgg cctgaattgg tgtagtagtt
    15961 gacgccagca acaccatatc cctggctatc caccaggcga ccttctgaga gaatgatttc
    16021 cgaaggttga tactgataaa actgttccgc gttagccgac acgaaggagg cgttcagatc
    16081 cggttttgtt cccggagtcg tgacggggac taccggtgaa gtatgagtgg atggcgcttt
    16141 atcagtcgcg gcattgtttt ccacctcttc attgaccagc tttttgaact cttccggtgc
    16201 cagatcgatt tgcttataca gcgagtcgaa acgtttactc tcgatcaccg aggagaactc
    16261 caggcacacc tgttctgtat tcgccgggca actgttcatg gaggtgacca gcgagagcgc
    16321 attgcttttc ttgttgtcgg aacccgccag ttcttgcgcg tcctcaagac taaacgacac
    16381 tttttcaacc gcacgcaggc tacgcgcagc ttctgactgg gtgtcgaagg tagcaattgt
    16441 cgtgttgttc cctgccacac aggtgacttt gtcgcctggt gtaaaggtaa agccatcgct
    16501 ggattcatca ttacaggtga tatcaccagt tacccgcagg cttccgccca gagtcagata
    16561 acccgttttc gtaggaacag gttctggctc cggttctggt gttggctcag gatcaggtgt
    16621 cggttccggc gtaggttctg ggtccggcgt tggctcaggc gtcggctccg ggtttggtgt
    16681 tggatcaggt ttcacttccg gcaaagaccc tgttccagaa tctacaggcg gcgtatcgga
    16741 ggaagatccg gagccaccgc catcacaacc ggctaacagg gttgcactca aaatagccgc
    16801 taaaagcgat ttcttatatt taaatttctt attcattaat aacgcaagtg acaaaacaat
    16861 gttaaa
//
LOCUS       DAPGUL010000100        16791 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.102, whole genome shotgun sequence.
ACCESSION   DAPGUL010000100 DAPGUL010000000
VERSION     DAPGUL010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16791
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.102"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(65..1615)
                     /gene="cueO"
                     /locus_tag="RHX21_003459"
     CDS             complement(65..1615)
                     /gene="cueO"
                     /locus_tag="RHX21_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multicopper oxidase CueO"
                     /protein_id="HDV1988603.1"
                     /translation="MQRRDFLKYSVALGVASALPLWSRAVFAAERPTLPIPDLLTTDA
                     RNRIQLTIGAGQSTFGEKTATTWGYNGNLLGPAVKLQRGKAVTVDIYNQLTEETTLHW
                     HGLEVPGEVDGGPQGIIPPGGKRSVTLNVDQPAATCWFHPHQHGKTGRQVAMGLAGLV
                     VIEDDEILKLMLPKQWGIDDVPVIVQDKKFNADGQIDYQLDVMTAAVGWFGDTLLTNG
                     AIYPQHAAPRGWLRLRLLNGCNARSLNFATSDNRPLYVIASDGGLLPEPVKVSELPVL
                     MGERFEVLVEVNDNKPFDLVTLPVSQMGMAIAPFDKPHPVMRIQPIAISASGALPDTL
                     SSLPALPSLEGLTVRKLQLSMDPMLDMMGMQMLMEKYGDQAMAGMDHSQMMGHMGHGN
                     MNHMNHGGKFDFHHANKINGQAFDMNKPMFAAAKGQYERWVISGVGDMMLHPFHIHGT
                     QFRILSENGKPPAAHRAGWKDTVKVEGNVSEVLVKFNHNAPKEHAYMAHCHLLEHEDT
                     GMMLGFTV"
     gene            1781..2128
                     /locus_tag="RHX21_003460"
     CDS             1781..2128
                     /locus_tag="RHX21_003460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414664.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YacC family pilotin-like protein"
                     /protein_id="HDV1988604.1"
                     /translation="MKTFFRTVLFGSLMAVCANSYALSESEAEDMADLTAVFVFLKND
                     CGYQNLPNGQIRRALVFFAQQNQWDLSNYDTFDMKALGEDSYRDLSGIGIPVAKKCKA
                     LARDSLSLLAYVK"
     gene            2234..3100
                     /gene="speE"
                     /locus_tag="RHX21_003461"
     CDS             2234..3100
                     /gene="speE"
                     /locus_tag="RHX21_003461"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HDV1988605.1"
                     /translation="MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFG
                     RVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVE
                     SITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCT
                     DPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGF
                     YQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAIHTAAFALP
                     QYLQDALASQPS"
     gene            3116..3910
                     /gene="speD"
                     /locus_tag="RHX21_003462"
     CDS             3116..3910
                     /gene="speD"
                     /locus_tag="RHX21_003462"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HDV1988606.1"
                     /translation="MKKLKLHGFNNLTKSLSFCIYDICYAKTAEERDGYIAYIDELYN
                     ANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDKTEHPGPLP
                     ETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDI
                     VTIDYRVRGFTRDINGMKHFIDHEINSIQNFMSDDMKALYDMVDVNVYQENIFHTKML
                     LKEFDLKHYMFHTKPEDLTDSERQEITAALWKEMREIYYGRNMPAV"
     gene            complement(3948..4310)
                     /locus_tag="RHX21_003463"
     CDS             complement(3948..4310)
                     /locus_tag="RHX21_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414661.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YacL family protein"
                     /protein_id="HDV1988607.1"
                     /translation="MDYEFLRDITGVVKVRMSMGHEVVGHWFNEEVKENLALLDEVEQ
                     AAHALKGSERSWQRAGHEYTLWMDGEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCG
                     VEDFLQVVAAYRNFVQQK"
     gene            complement(4485..7082)
                     /gene="acnB"
                     /locus_tag="RHX21_003464"
     CDS             complement(4485..7082)
                     /gene="acnB"
                     /locus_tag="RHX21_003464"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aconitate hydratase
                     2/2-methylisocitrate dehydratase"
                     /protein_id="HDV1988608.1"
                     /translation="MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEF
                     LLDLLTNRVPPGVDEAAYVKAGFLAAIAKGEAKSPLLTPEKAIELLGTMQGGYNIHPL
                     IDALDDAKLAPIAAKALSHTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRP
                     ALAEKLTVTVFKVTGETNTDDLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVG
                     PIKQIEALQQKGFPLAYVGDVVGTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGG
                     KIAPIFFNTMEDAGALPIEVDVSNLNMGDVIDVYPYKGEVRNHETGELLATFELKTDV
                     LIDEVRAGGRIPLIIGRGLTTKAREALGLPHSDVFRQAKDVAESDRGFSLAQKMVGRA
                     CGVKGIRPGAYCEPKMTSVGSQDTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPK
                     PVDVNTHHTLPDFIMNRGGVSLRPGDGVIHSWLNRMLLPDTVGTGGDSHTRFPIGISF
                     PAGSGLVAFAAATGVMPLDMPESVLVRFKGKMQPGITLRDLVHAIPLYAIKQGLLTVE
                     KKGKKNIFSGRILEIEGLPDLKVEQAFELTDASAERSAAGCTIKLNKEPIIEYLNSNI
                     VLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEADADAEYAAVIDIDLADIKEPIL
                     CAPNDPDDARPLSAVQGEKIDEVFIGSCMTNIGHFRAAGKLLDAHKGQLPTRLWVAPP
                     TRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVADGATVVSTSTRNFPNRLG
                     TGANVFLASAELAAVAALIGKLPTPEEYQTYVAQVDKTAVDTYRYLNFNQLSQYTEKA
                     DGVIFQTAV"
     gene            7437..9194
                     /locus_tag="RHX21_003465"
     CDS             7437..9194
                     /locus_tag="RHX21_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3300 domain-containing protein"
                     /protein_id="HDV1988609.1"
                     /translation="MKMTLPFKPHVLALICSAGLCAASTGLYIKSRTVEAPVEPQSTQ
                     QTAPDITAVTLPATVSAPPVTPAVVKSAFSTAQIDQWVAPVALYPDSLLSQVLMASTY
                     PANVAQAVQWSHDNPLKQGDAAIQAVSDQPWDASVKSLVAFPQLMALMGENPQWVQNL
                     GDAFLAQPQDVMDSVQRLRQLAQQTGSLKSSTEQKVITTTKKAVPVTQTVTAPVIPSN
                     TVSTASPVITEPATTVISIEPANPDVVYIPNYNPTVVYGNWANTAYPPVYLPPPAGEP
                     FIDSFVRGFGYSMGVATTYALFSSIDWDDDDHDHHHHDDDDYHHHDGGHRDGNGWQHN
                     GDNINIDVNNFNRITGEHLTDKNMAWRHNPNYRNGVPYHDQDMAKRFHQTDVNGGMSA
                     TQLPAPTRDSQRQAAASQFQQRTHAAPVITRDTQRQAAAQRFNEAENYGSYDDFRDFS
                     RRQPLTQQQKDAARQRYQSASPEQRQAVREKMQTNPQIQQRRDAARERIQSASPEQRQ
                     VFKEKVQQRPLNQQQRDNARQRVQSASPEQRQVFREKVQESRPQRLNDSNHTVRLNNE
                     QRSAVRERLSERGARRQER"
     gene            complement(9265..10689)
                     /gene="lpdA"
                     /locus_tag="RHX21_003466"
     CDS             complement(9265..10689)
                     /gene="lpdA"
                     /locus_tag="RHX21_003466"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDV1988610.1"
                     /translation="MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGV
                     CLNVGCIPSKALLHVAKVIEEAKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLA
                     GMAKGRKVKVVNGLGKFTGANTLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDP
                     RIWDSTDALELKEVPERLLVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDI
                     VKVFTKRISKKFNLMLETKVTAVEAKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPN
                     GKNLDAGKAGVEVDDRGFIRVDKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEV
                     IAGKKHYFDPKVIPSIAYTEPEVAWVGLTEKEAKEKGISYETATFPWAASGRAIASDC
                     ADGMTKLIFDKESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHE
                     SVGLAAEVFEGSITDLPNPKAKKK"
     gene            complement(11014..12906)
                     /gene="aceF"
                     /locus_tag="RHX21_003467"
     CDS             complement(11014..12906)
                     /gene="aceF"
                     /locus_tag="RHX21_003467"
                     /EC_number="2.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex
                     dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HDV1988611.1"
                     /translation="MAIEIKVPDIGADEVEITEILVKVGDKVEAEQSLITVEGDKASM
                     EVPSPQAGIVKEIKVSVGDKTQTGALIMIFDSADGAADAAPAQAEEKKETAPAAAPAA
                     AAAKDVNVPDIGSDEVEVTEILVKVGDKVEAEQSLITVEGDKASMEVPAPFAGTVKEI
                     KVNVGDKVSTGSLIMVFEVAGEAGAAAPAAKQEAAPAAAPAPAAGVKEVNVPDIGGDE
                     VEVTEVMVKVGDKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIM
                     IFEVEGAAPAAAPAKQEAAAPAPAAKAEAPAAAPAAKAEGKSEFAENDAYVHATPLIR
                     RLAREFGVNLAKVKGTGRKGRILREDVQAYVKEAIKRAEAAPAATGGGIPGMLPWPKV
                     DFSKFGEIEEVELGRIQKISGANLSRNWVMIPHVTHFDKTDITELEAFRKQQNEEAAK
                     RKLDVKITPVVFIMKAVAAALEQMPRFNSSLSEDGQRLTLKKYINIGVAVDTPNGLVV
                     PVFKDVNKKGIIELSRELMTISKKARDGKLTAGEMQGGCFTISSIGGLGTTHFAPIVN
                     APEVAILGVSKSAMEPVWNGKEFVPRLMLPISLSFDHRVIDGADGARFITIINNTLSD
                     IRRLVM"
     gene            complement(12921..15584)
                     /gene="aceE"
                     /locus_tag="RHX21_003468"
     CDS             complement(12921..15584)
                     /gene="aceE"
                     /locus_tag="RHX21_003468"
                     /EC_number="1.2.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008814576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring),
                     homodimeric type"
                     /protein_id="HDV1988612.1"
                     /translation="MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEA
                     RKGGVNVAAGTGISNYINTIPVEEQPEYPGNLELERRIRSAIRWNAIMTVLRASKKDL
                     ELGGHMASFQSSATIYDVCFNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTQ
                     EQLDNFRQEVHGNGLSSYPHPKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLK
                     DTSKQTVYAFLGDGEMDEPESKGAITIATREKLDNLVFVINCNLQRLDGPVTGNGKII
                     NELEGIFEGAGWNVIKVMWGSRWDELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYV
                     REHFFGKYPETAALVADWTDEQIWALNRGGHDPKKIYAAFKKAQETKGKATVILAHTI
                     KGYGMGDAAEGKNIAHQVKKMNMDGVRHIRDRFNVPVSDADIEKLPYITFPEGSEEHT
                     YLHAQRQKLHGYLPSRQPNFTEKLELPSLQDFGALLEEQSKEISTTIAFVRALNVMLK
                     NKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQQYTPQDREQVAYYKEDEKGQIL
                     QEGINELGAGCSWLAAATSYSTNNLPMIPFYIYYSMFGFQRIGDLCWAAGDQQARGFL
                     IGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERMYGEK
                     QENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETIEGSKGKVQLLGSGSILRHVR
                     EAAEILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHPLETPRVPYIAQVMNDAPA
                     VASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRHHFEVDASYVVVAALGE
                     LAKRGEIDKKVVADAIAKFNIDADKVNPRLA"
     gene            complement(15745..16509)
                     /gene="pdhR"
                     /locus_tag="RHX21_003469"
     CDS             complement(15745..16509)
                     /gene="pdhR"
                     /locus_tag="RHX21_003469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex transcriptional
                     repressor PdhR"
                     /protein_id="HDV1988613.1"
                     /translation="MAYSKIRQPKLSDVIEQQLEFLILEGTLRPGEKLPPERELAKQF
                     DVSRPSLREAIQRLEAKGLLLRRQGGGTFVQSSLWQSFSDPLVELLSDHPESQYDLLE
                     TRHALEGIAAYYAALRSTDEDKERIRELHHAIELAQQSGDLDAESNAVLQYQIAVTEA
                     AHNVVLLHLLRCMEPMLAQNVRQNFELLYSRREMLPLVSSHRTRIFEAIMAGKPEEAR
                     EASHRHLAFIEEILLDRSREESRRERSLRRLEQRKN"
BASE COUNT         3888 a         4666 c         4128 g         4109 t
ORIGIN      
        1 gatttgcgtt tgtcatcagt ttaatgcccg gagagatccg ggcatatttc cgaatacggt
       61 ctttttatac cgtaaaccct aacatcatcc ccgtatcttc atgctccagc agatggcagt
      121 gcgccatata agcatgttct ttcggtgcgt tgtgattaaa cttcaccagc acttcactga
      181 cattgccttc taccttaacg gtatctttcc agcccgcgcg atgagccgct ggcggtttgc
      241 cattttctga caagatacgg aactgggtgc cgtgaatatg gaacggatgc agcatcatgt
      301 cgcccacgcc agagataacc caacgttcgt actgcccttt cgccgccgca aacatcggct
      361 tattcatatc aaacgcctga ccgttgattt tattggcatg gtggaaatcg aacttcccgc
      421 catggttcat atgattcata ttgccgtgcc ccatatggcc catcatctgg ctatgatcca
      481 tcccggccat cgcctgatcg ccatatttct ccatcagcat ctgcatcccc atcatatcga
      541 gcatcgggtc catagaaagt tgcagcttgc gtaccgtcag cccttccagc gaaggtaacg
      601 caggcaggct acttaatgtg tctggcaaag caccggaggc actaatagca atcggctgaa
      661 tccgcattac cggatgcggc ttgtcaaacg gcgcaatcgc catccccatc tggctgaccg
      721 gtagcgtcac caggtcaaag ggtttgttgt cgttaacctc caccagcact tcaaaacgct
      781 cgcccatcag caccggcagc tcgctcacct tcaccggttc aggtagcaga ccaccgtcgc
      841 tggcaatcac atacagcggg cgattgtcgc tggtggcgaa attgagcgag cgggcattac
      901 agccattgag caaacgcagg cgcagccaac cacgtggggc agcgtgttgt gggtagattg
      961 caccgttggt cagcagcgta tcgccaaacc agcccacggc ggcggtcatc acatccagtt
     1021 gataatcaat ctgcccatca gcgttaaatt ttttatcctg aacaatcacc ggaacatcat
     1081 cgatacccca ctgttttggc agcattaatt tcaggatctc gtcatcttca attaccacca
     1141 gcccagccaa ccccatcgcc acctgtcgcc cggtcttgcc atgttgatgt ggatggaacc
     1201 agcaagtagc ggcaggttga tcaacgttca acgtcaccga gcgcttgcca cctggcggaa
     1261 taattccctg cgggccgccg tcgacttcac ccggtacttc cagcccgtgc cagtgcaacg
     1321 tcgtctcttc cgtcagttgg ttatagatat caaccgttac cgctttgccg cgctgtaatt
     1381 tcaccgccgg ccccagcaga ttgccgttat agccccaggt agttgcagtt ttctcgccaa
     1441 aggtagactg acctgcgcca atagttaact gaatgcgatt acgggcatcg gtcgtgagca
     1501 aatcagggat cggtaacgtt gggcgttccg ccgcaaagac tgcgcggctc cacagcggca
     1561 aggctgaagc cacacccagc gcgacggaat attttaagaa atcacgacgt tgcatagtta
     1621 tttccttatt cttaagcagg cgaaacaaaa tcaaacgttg agcatagtcc ttccccttac
     1681 gggaaggtca agccgcagac acaatttaat cgacaataat ggtcgtcgcc tcgctcgcag
     1741 tgtgctaacg tttatcttct ttaagcccct ggtagaagca atgaagacgt ttttcagaac
     1801 agtgttattc ggcagcctga tggccgtttg cgcaaacagt tacgcgctca gcgagtctga
     1861 agccgaagat atggccgatt taacggcagt ttttgtcttt ctgaagaacg attgtggtta
     1921 ccagaactta cctaacgggc aaattcgtcg cgcactggtc tttttcgccc agcaaaacca
     1981 gtgggatctc agtaattacg acaccttcga catgaaagcc ctcggtgaag acagctaccg
     2041 cgatctcagc ggcattggca ttcccgtcgc taaaaagtgc aaagccctgg cccgcgattc
     2101 cttaagcctg cttgcctacg tcaaataatc cctgatacct ttttgtagaa atattgaccg
     2161 tgcatccgcg gtcaatgtta gctattatgt tgcgcccttt ttttacgggt gttaacaaag
     2221 gaggtatcaa cccatggccg aaaaaaaaca gtggcatgaa acgctacacg accagtttgg
     2281 gcagtacttt gcggtagata acgttctgta tcatgaaaag accgatcacc aagatctgat
     2341 catttttgag aacgctgcat ttggtcgcgt aatggcgctg gatggcgtag tacaaaccac
     2401 cgagcgcgac gagtttatct atcatgagat gatgacccat gttccgctac tggcccacgg
     2461 tcacgcgaaa catgtgctga ttatcggcgg cggcgacggt gccatgctgc gtgaagtaac
     2521 ccgacataaa aacgttgagt caatcacgat ggtggaaatc gatgcgggtg tcgtatcgtt
     2581 ctgccgtcag tatctaccca accataacgc cggtagctac gacgatccgc gctttaagct
     2641 ggtgatcgac gatggcgtca atttcgttaa tcaaaccagc cagacctttg atgtcattat
     2701 ctccgactgc accgatccta tcggtcccgg cgaaagcctt ttcacttcgg cattttatga
     2761 aggctgcaaa cgttgcctga atcctggcgg tatcttcgtc gcacaaaacg gcgtctgctt
     2821 tttacagcag gaagaagcca tcgacagcca tcgcaaactc agccattact tcagcgacgt
     2881 tggcttttat caggcggcga ttccgaccta ttacggcggt atcatgactt ttgcatgggc
     2941 gacagataac gacgccttac gccatctctc aaccgaaatt attcaggcgc gttttctcgc
     3001 ttctggcctg aaatgccgtt attacaatcc ggcaatccat acggcagctt ttgccttacc
     3061 tcagtatctg caagacgcac tggcttcaca gccgtcctaa ggagaagata agaaattgaa
     3121 aaaactgaaa ctgcatggct ttaataatct gaccaaaagt ctgagttttt gtatttacga
     3181 tatctgctac gccaaaactg ccgaagagcg cgacggttat attgcttata tcgatgaact
     3241 ctataatgcc aaccgtctga ccgaaatcct gtcagaaacc tgttccatta tcggggccaa
     3301 tattcttaac atcgcccgcc aggattacga accacagggt gccagcgtca ctattctggt
     3361 gagtgaagaa ccggttgacc cgaaactcat cgacaaaaca gaacaccccg gcccactgcc
     3421 agaaacggtc gttgcccatc tcgataaaag tcatatttgc gtacatacct acccggaaag
     3481 tcatcctgaa ggcggtttat gtaccttccg cgccgatatt gaagtctcta cctgcggcgt
     3541 gatttctccg ctgaaggcgc tgaattacct gatccaccag cttgagtccg atatcgtaac
     3601 cattgattat cgcgtgcgcg gttttacccg cgacattaac ggtatgaagc actttatcga
     3661 ccatgagatt aattcgattc agaactttat gtctgacgat atgaaggcgc tgtatgacat
     3721 ggtggatgtg aacgtctatc aggaaaatat cttccatacc aagatgttgc ttaaagagtt
     3781 cgaccttaag cactacatgt tccacaccaa accggaagat ttaaccgaca gcgagcgcca
     3841 ggaaattacc gctgcgctgt ggaaagaaat gcgcgagatt tattacgggc gcaatatgcc
     3901 agctgtttaa cggctctggc ggagctccca ggctccgcca gatttattta cttctgctgc
     3961 acgaaattgc ggtaagccgc cacgacctgc agaaaatcct caacgccgca tagcgacagg
     4021 ctttcttcgt cgtagtagtt catcccctct tccatttcat cgccagcgaa ttccagttga
     4081 ttggcgcgaa ccatcacctc ttcaccgtcc atccacaggg tgtattcatg ccctgcccgt
     4141 tgccaggacc gttcgctacc tttcagtgcg tgcgctgctt gttccacttc atcaagcaag
     4201 gccaggtttt ctttcacctc ttcattaaac cagtgcccga ccacttcatg ccccatggac
     4261 atacgcacct ttaccactcc ggtaatatcg cgcagaaatt cgtaatccat agtgtgttcc
     4321 tctgctcccg gcaatgcgcc gaaatcgcat cgcgccattg atgtaattat cgcagcctta
     4381 ccggagaaaa acagcggaac ggcgatggtt tagaaataaa aaatgcccgg gaatctcatt
     4441 caccgggcat tgtgtcgttt atgcgcagcg cgtgcgctta cttattacac cgcagtctgg
     4501 aaaatcaccc catcggcttt ttcggtgtac tgagaaagct ggttgaagtt cagataacga
     4561 taagtatcaa cggcagtttt atctacttgc gcaacgtagg tctggtactc ttccggcgtc
     4621 ggcagtttgc caatcagcgc cgcaacagcc gccagttctg cagaagccag gaagacattc
     4681 gcgccagtcc ccagacggtt cgggaagtta cgggtagagg tggaaaccac cgtcgcaccg
     4741 tctgctacac gcgcctggtt acccatacac agagaacagc ccgggatctc gatacgagcc
     4801 ccgctcttac cgaagacgct gtagtagcct tcttcagtca actgtgcggc gtccatacgg
     4861 gttggcggtg ccacccacag gcgggtcggc aactggcctt tatgcgcatc cagcagttta
     4921 cccgcagcac ggaagtgacc gatgttagtc atgcaagaac cgataaatac ttcgtcgatc
     4981 ttctcgccct gtaccgcaga cagcggacgc gcgtcatccg ggtcgttcgg tgcacagagg
     5041 attggctctt taatatccgc cagatcgatg tcgatcactg ccgcgtattc agcatctgca
     5101 tcggcttcca gcagctcagg attcgccagc catttttcca tgccctgaat acgacgttcg
     5161 agggtacgac gatcgccata accttccgcg atcatccact tcagcaggac gatgttagag
     5221 ttcaggtatt cgatgatcgg ttctttgttc agcttgatag tacaaccagc ggcagaacgc
     5281 tcagcggacg catcggtcag ttcaaatgcc tgctcaactt tcagatccgg cagaccttca
     5341 atttccagaa tgcgaccaga gaagatgttt ttcttgcctt tcttctcaac ggtcagcaga
     5401 ccttgtttga tcgcatacag cgggatcgcg tgtaccagat cgcgcagggt gatgcccggc
     5461 tgcattttgc ctttgaagcg caccagaacg gattccggca tatccagcgg cattacgcct
     5521 gttgcggctg caaatgccac cagaccagaa cccgccggga aagagatacc gatcgggaaa
     5581 cgggtatggg agtcaccacc ggtaccgacg gtatccggca gcagcatacg gttcagccag
     5641 gagtggatta cgccgtcacc cggacgcagc gacacaccac cacggttcat aatgaagtcc
     5701 ggcagcgtgt ggtgcgtgtt cacgtcaact ggcttcggat acgccgcggt atggcagaaa
     5761 gactgcatca ccaggtcagc cgagaagccc aggcacgcca ggtctttcag ttcatcacgg
     5821 gtcatcgggc cggtggtgtc ctgagagcct acagaagtca ttttcggttc gcagtacgcg
     5881 cccggacgaa tgcctttcac gccacaggca cggcctacca ttttctgcgc cagcgagaag
     5941 ccgcgatcgc tctcagcgac atctttcgcc tgacggaaca catcactgtg cggcagacca
     6001 agtgcttcac gcgctttggt ggtcaggcca cgcccgataa tcagcggaat acgaccgcca
     6061 gcacgcactt catcaatcag cacgtcggtt ttcagttcga aggtcgccag cagttcgccg
     6121 gtttcgtggt tacgcacttc acctttgtac gggtaaacgt caatcacgtc gcccatgttc
     6181 aggttagaga cgtcgacttc gattggcagt gcacccgcgt cttccatcgt gttaaagaag
     6241 atgggtgcaa ttttaccgcc gaggcacaaa ccaccgccgc gtttgttcgg cacatgtgga
     6301 atatcatcgc ccataaacca cagaacggag ttagtggcgg atttacgcga agaacccgta
     6361 cccacaacgt caccgacgta cgccagcggg aaacctttct gttgcagagc ttcgatttgc
     6421 ttgatcggac caacaacacc tggctggtct ggctcaatac cttcacgggc gtttttcagc
     6481 atcgccagcg cgtgcagtgg gatatccggg cgtgaccacg catccggtgc cggagaaagg
     6541 tcatcggtgt tagtttcgcc agtgactttg aagacggtaa cggtcagttt ttcagccagc
     6601 gccgggcgat tcaggaacca ttcggcatcc gcccaggact gcataacctg cttcgcatat
     6661 tcgttgcctg ctttcgcttt ctcttctacg tcatagaagt tatcgaacat cagcagcgtg
     6721 tgagaaagtg ctttggcagc aataggtgcc agtttggcat catccagcgc gtcgatcagc
     6781 ggatgaatgt tgtaaccacc ctgcatggtg cccagcagtt cgatggcttt ttccggagtc
     6841 agcagagggg atttggcttc gcctttcgcg atagcagcca ggaagcctgc tttgacatag
     6901 gcggcttcat cgacgcctgg gggaacacgg ttggttaaca gatctaacag gaattcttct
     6961 tcgcccgcgg gcgggttttt cagcagctct acaagtgcgg ccatttggtt tgcatccagg
     7021 ggtttgggcg caatcccctc agcggcacgc tcagctacgt gcttacggta ttcttctagc
     7081 acgacggttc tcctcgctct cattgtcata gtgcggcagg cgattctctt cacgctcctg
     7141 tgagacagca gtttgtaggg taaatgccca gtaccgcaac gggcagaata gcaggatttt
     7201 gacgatgtgt taatctgttt acaaaaaagc aacataaaaa agtggctgaa tcgttaagga
     7261 tggtctagag attgtttccc tccgtaaaaa cttcgttaat tcgcatggtg ataatcacct
     7321 ttctcaacga atcccaagat tagtcaaaat ttaaactacc gcctctttat actcggattc
     7381 acagcacctg cgggtggcag ttcgccgacc attgcgattt ccttgagatc cgaattatga
     7441 aaatgacttt gccgtttaaa ccccatgtgc tggcgctaat ttgcagtgcc gggctttgtg
     7501 ccgcctctac cgggctatat ataaaaagcc gcacagtgga agcgcctgtg gaaccgcaat
     7561 cgacacaaca gactgcgcct gacatcaccg cagttacgct tcctgcaacg gtttccgcac
     7621 cgcccgtaac gcccgccgtc gtcaaatccg cattcagcac tgcacaaatc gatcaatggg
     7681 ttgcgcctgt cgcgctgtac cccgattctc tgctttcaca agtgttaatg gcatcaacct
     7741 atccggcaaa cgttgctcaa gcagtgcaat ggtcgcacga taatccactt aaacaaggcg
     7801 atgctgctat tcaggcggta tctgaccagc cgtgggacgc cagcgttaaa tcactggtgg
     7861 cctttccaca attgatggca ttgatgggcg aaaacccgca atgggtgcaa aacctgggcg
     7921 atgcttttct ggcgcagccg caggacgtga tggactcggt acagcgattg cggcaactgg
     7981 cgcaacaaac cggctcgctg aagtcatcaa ccgaacagaa agttattacc acaacgaaga
     8041 aagctgtacc ggtaacacag acagtcacgg ctcccgtcat accatccaat accgtttcaa
     8101 ctgccagccc cgtcattaca gagcctgcaa caaccgtcat ttccattgag cccgccaatc
     8161 ctgatgtggt ctatattccc aactacaacc caaccgtggt ttacgggaac tgggccaata
     8221 ctgcgtatcc gccggtttat ctgccaccac cagccggaga accgtttatt gacagctttg
     8281 tgcgcggatt cggctatagc atgggtgttg ctaccacgta cgcactattc agcagcatcg
     8341 actgggacga cgacgatcat gaccatcatc atcatgacga tgatgattat catcaccacg
     8401 atggcggtca tcgtgacggt aatggctggc aacacaacgg cgacaacatc aatatcgacg
     8461 tcaacaattt caaccgtatc accggtgagc atcttactga taagaatatg gcatggcggc
     8521 acaatccaaa ctaccgtaat ggtgtgccct atcatgatca ggatatggca aagcggtttc
     8581 atcaaaccga tgtcaacggc ggaatgagcg ccacgcagct acctgctcca acacgcgaca
     8641 gccagcgtca ggcggcagca agtcagtttc agcaacgaac acacgccgcc cccgtcatta
     8701 cacgagatac ccaacgtcag gcagcggcac agcggtttaa tgaagctgaa aactatggga
     8761 gctatgacga cttccgcgac ttcagccgtc gccaaccact gacccagcaa caaaaggacg
     8821 ccgctcgtca gcgttatcag tcggcctcgc ctgagcagcg ccaggcagtc cgcgagaaaa
     8881 tgcagactaa cccacagatc cagcagcgaa gagacgcagc gcgtgagcgt attcagtcag
     8941 cctcgcctga gcagcgccag gtgtttaagg aaaaagtaca gcagcgccca ctgaaccaac
     9001 agcaacgtga taacgcccgc cagcgtgttc aatcagcatc acctgaacaa cgtcaggttt
     9061 ttcgggaaaa agttcaggag agccgcccac aacgtctaaa cgacagtaac catactgtca
     9121 ggctgaataa cgagcaacgg tcagcagtac gcgaacgtct ctctgagcgc ggagcaaggc
     9181 gacaggaaag gtaaattgca gacgtaaaaa aagcggcgtg gttagccgct tttttaattg
     9241 ccggatgttc cggcaaacga acacttactt cttcttcgct ttcgggttcg gcaggtcggt
     9301 aatgctacct tcgaacactt ctgccgccag gcccacagac tcgtgcagag tcgggtgcgc
     9361 gtggatggtc agtgcgatgt cttcagcatc acaacccatt tcgattgcca ggccgatttc
     9421 acccagcagc tcgccgccgt tggtaccgac aatcgcacca ccgatcacac ggtgagattc
     9481 tttgtcgaaa atcagcttgg tcataccgtc tgcgcagtcg gaagcgatag cacgaccaga
     9541 agcagcccac gggaaggtgg cggtttcata gctgatgcct ttctctttcg cttctttctc
     9601 agtcagacct acccatgcaa cttctggttc ggtataggcg atggacggga taactttcgg
     9661 atcgaagtag tgtttcttac cggcgataac ttcagcggca acgtgacctt cgtgaacacc
     9721 tttgtgtgcc agcatcggct gaccgacgat atcgccgata gcaaagatgt gcggtacgtt
     9781 ggtacgcagc tgtttgtcaa cgcggatgaa accacggtcg tccacttcca cgccagcttt
     9841 gcctgcgtcg aggtttttac cgttcggcac acgaccaatc gctaccagca cggcgtcgta
     9901 acgctgcggt tcagcgggtg cttttttgcc ttccatcgtc acataaatac cgtcttcttt
     9961 cgcttcaacg gcggtaactt tggtttccag catcaggttg aatttcttgc tgatacgctt
    10021 ggtgaagact ttaacgatgt ctttgtcagc tgccgggata acctggtcga acatttcaac
    10081 cacgtcaatc tgtgaaccca gcgcgtggta tacggtgccc atttccagac cgatgatacc
    10141 gccacccatt accagcaggc gttctggtac ttctttcagt tccagcgcgt cagtggagtc
    10201 ccagatacgc ggatcttcat gcggaataaa cggcagttgg atcgggcgag aacccgctgc
    10261 aatgatcgcg ttgtcgaagt tgatcacggt tttaccgttc tcaccttcaa cttccagggt
    10321 gttagccccg gtaaatttac ccagaccgtt gaccactttg actttgcggc ctttcgccat
    10381 accagccaga ccaccggtca gctgattgat cactttctct ttccaggtac gaatcttgtc
    10441 aatatcggtt ttcggttcgc cgaagacgat accgtgttca gccagcgctt tggcttcttc
    10501 gataactttt gctacgtgca gcagtgcttt agaagggata cagccgacgt tcaggcaaac
    10561 accgccaagg gtgttgtaac gttctacgat tacggtttcc agacctaaat cagcgcaacg
    10621 gaaggcagcg gagtaacctg cggggcctgc cccaagtacc acgacctgag ttttgatttc
    10681 agtactcatc atgacctcta tatatttatc tccggcggtc atacccgtcg tctttcaggc
    10741 cgcagcggcg ttagcttcac gccctcaccc cagtcactta cttatgtaag ttcctgggga
    10801 ttctggcgct tgctaccttg ctgcacccag aaatccatag ggtatgtgaa gtaataccct
    10861 aaccaccacc gggtcgttct atccgtcggt attttacaaa attgttaaca atttttaaac
    10921 aacaaacggc aaccgatttg tctattcgct aataacctca atacattcat gagattacca
    10981 gaaaaaagcc ggccgttggg ccggctcttt tacttacatc accagacggc gaatgtcaga
    11041 cagcgtgttg ttaatgatgg taatgaaacg ggcaccatca gcaccgtcga tcacgcggtg
    11101 gtcgaaggag agagaaatcg gcagcatcag acgcggcacg aactctttac cattccacac
    11161 cggctccatc gcggacttgg aaacgccgag gatagccact tccggcgcgt tcacaatcgg
    11221 cgcgaagtgg gtagtaccca ggccgccgat gctggagatg gtgaagcaac cgccctgcat
    11281 ttcgcccgca gtcagcttac cgtcacgcgc tttcttagaa atagtcatca gctcgcgaga
    11341 cagctcgatg atgcctttct tgttgacgtc tttgaatacc ggaacaacca gaccgttcgg
    11401 ggtatccacc gccacaccga tgttgatgta tttcttcagg gtcagacgct gaccgtcttc
    11461 cgacaacgaa ctgttgaagc gaggcatctg ctcaagagct gcagcaacgg ctttcatgat
    11521 gaagacaacc ggggtgatct tcacatccag cttacgtttc gccgcttctt cgttctgctg
    11581 tttacggaac gcttccagct cggtgatatc ggttttgtcg aagtgagtaa catgcgggat
    11641 catcacccag ttacggctca ggttcgcacc agaaattttc tggatacggc ccagttccac
    11701 ttcttcgatt tcaccaaact tgctgaagtc caccttcggc cacggcagca tgcctgggat
    11761 accgccgcca gtcgccgccg gagctgcttc tgcacgtttg atagcttctt tcacgtaagc
    11821 ctgaacgtct tcgcgcagga tacgaccttt acggccagtg cccttcactt tcgccaggtt
    11881 aacgccaaac tcgcgtgcca gacggcggat cagcggagtc gcgtgaacgt aagcgtcgtt
    11941 ttctgcaaat tcagatttgc cttccgcttt cgcagccggt gctgctgccg gagcttcagc
    12001 ttttgctgcc ggagccggcg ctgccgcttc ctgtttcgca ggagctgccg caggcgctgc
    12061 gccttcaact tcgaagatca taatcagcga gccagttttc actttatcgc caacgttgac
    12121 tttcagttcc ttcacgacgc ctgcaaacgg agccggaact tccatagaag ctttgtcgcc
    12181 ttctacggta atcagtgact gttcagcggc aactttgtcg cccactttca ccatcacttc
    12241 ggtcacttca acttcgtcac cgccgatatc cggaacgtta acttctttca cgccagccgc
    12301 tggtgcaggg gccgctgccg gagccgcttc ctgtttagcc gccggagctg ccgcgcctgc
    12361 ttcacccgcg acttcgaaga ccataatcag cgagccggta gacactttgt cacccacgtt
    12421 cactttgatc tctttcacgg tgccagcaaa cggagccgga acttccatag acgctttatc
    12481 gccttctacg gtgatcagcg actgttcagc ttcaacttta tcgccaactt tcaccaggat
    12541 ttcggtcact tcaacttcgt cgctgccgat atccggaacg ttaacgtctt ttgccgctgc
    12601 agccgctggt gctgctgccg gagctgtttc tttcttctct tctgcctgag caggtgcagc
    12661 gtctgctgca ccgtcggcgg aatcgaaaat cataatcagt gcgccggtct gggttttatc
    12721 gccaacagag actttgatct ctttaacgat acccgcctgc ggagacggaa cttccataga
    12781 ggctttgtcg ccttctacgg tgatcagcga ctgttcggct tcaactttgt cgcccacttt
    12841 gaccaggatc tcggtgattt caacttcatc agccccgatg tccggtactt tgatttcgat
    12901 agccattatt cttttacctc ttacgccaga cgcgggttaa ctttatctgc atcgatgttg
    12961 aatttggcga ttgcgtcagc aaccactttc ttatcgattt cgccacgttt agccagttcg
    13021 cccagcgccg ctacaaccac gtaggaagca tcaacttcga agtggtgacg caggttctca
    13081 cggctgtcgg aacgaccgaa gccatcagta cccagtacgc ggtagtcgtc agccggtacg
    13141 taagtacgga cctgctcagc gaacagtttc atatagtcgg tagatgccac tgccggagcg
    13201 tcgttcatca cctgagcgat atacggaacg cgcggagttt ccagcgggtg cagcatgttc
    13261 cagcgttcac aatcctgacc atctcgcgcc agttcggtga aggaggtcac gctataaacg
    13321 tcagaaccta cgccgtaatc tttcgccagg atctctgccg cttcacggac gtgacgcagg
    13381 atggaaccgg agcccagcag ctgaacttta cctttgctac cttcaatggt ttcgagtttg
    13441 tagatacctt tacggatacc ttcctcagca ccttccggca ttgccggcat gtggtagttt
    13501 tcgttcagcg tagtgatgta gtagtaaacg ttctcttgtt tttcaccgta catacgctcc
    13561 agaccgtcat gcataatgac agcaacttcg taagcgtaag ccgggtcgta agagatacag
    13621 ttcgggatag tcagcgactg aatgtggctg tgaccatctt cgtgctgcag accttcaccg
    13681 ttcagggtgg tacgaccgga agtaccgccg atcaggaagc cacgcgcttg ctggtcgcca
    13741 gccgcccagc acagatcgcc gatacgctgg aagccgaaca tcgagtaata gatgtagaac
    13801 ggaatcatcg gcagattgtt ggtgctgtaa gaggtcgccg ctgccagcca ggaacaacct
    13861 gcgcccaact cgttgatccc ttcctgcaga atctgacctt tctcgtcttc tttatagtaa
    13921 gcaacctgct cgcggtcctg cggggtgtac tgctgaccgt tcgggctgta aataccaatc
    13981 tgacggaaca gaccttccat accgaaagta cgcgcttcgt cggcgatgat cggtaccaga
    14041 cgatctttga tcgacttgtt cttcagcatt acgttcaggg cacgaacgaa agcgatagtg
    14101 gtagagatct ctttgctctg ctcttccagc agcgcgccga agtcttgcag gctcggcagc
    14161 tcaagcttct cggtgaagtt cggctgacgg cttggcagat aaccgtgcag tttctgacgc
    14221 tgtgcgtgca gataggtatg ctcttcagaa ccttccggga aggtgatgta cggcagtttt
    14281 tcgatatctg catcagacac cggcacattg aaacggtcgc ggatgtgacg cacgccgtcc
    14341 atgttcattt tcttaacctg gtgcgcgatg tttttacctt cagccgcgtc gcccatgccg
    14401 taacctttaa tggtatgagc aaggattact gtcgctttgc ctttggtttc ctgcgctttc
    14461 ttgaatgcag cgtagatttt cttcggatcg tgaccaccac ggttcagtgc ccagatctgt
    14521 tcgtcagtcc agtctgcaac cagtgctgcg gtttccggat atttaccgaa gaagtgttca
    14581 cgaacgtacg caccatcttt cgatttgaag gtctggtagt cgccgtcaac ggtttcgttc
    14641 atcagctgga tcagtttacc gctggtatct ttacgcagca gttcatccca acggctaccc
    14701 cacatcactt tgatcacgtt ccagccagca ccttcgaaga tgccttccag ttcgttgatg
    14761 atcttgccgt taccggtgac cgggccgtca agacgctgca ggttacagtt gataacgaag
    14821 accaggttat ccagtttttc acgggtagcg atggtgatcg cacctttgga ttccggttcg
    14881 tccatttcac cgtcgccgag gaacgcgtaa acggtctgtt tagaggtatc tttcaggcca
    14941 cggtgttcca gatatttcag gaatttagcc tggtaaatag caccaatcgg ccccagaccc
    15001 atagatacgg tcgggaactg ccagaattcc ggcatcagtt tcgggtgcgg ataggaagag
    15061 aggccattgc cgtgaacttc ctgacggaag ttatccagct gctcctgagt cagacgacct
    15121 tccaggaaag cacgagcgta cacgcccggg gagatgtggc cctggaagta aaccaggtcg
    15181 ccgccatcct gctcgttgcg tgcacggaag aagtggttaa agcacacatc ataaatggtt
    15241 gcggaagact ggaaggacgc catgtggccg cccagttcga gatctttttt cgacgcacgc
    15301 agcaccgtca tgatggcgtt ccagcgaata gctgaacgaa tacggcgttc cagttccaga
    15361 ttacccggat actccggttg ttcttcaacg gggatggtgt tgatgtagtt gctgatacct
    15421 gtgcctgcgg ctacgtttac accgcctttg cgggcttcag caagcagttg gtcgatcaga
    15481 tactgagcac gctcaacacc ttcttcacgg atgaccgatt cgatcgcctg gagccagtcg
    15541 cgagtttcga tcggatccac gtcatttggg aaacgttctg acatgggtta ttccttatct
    15601 atctaataac gttgagtttt ctggaacctg tcccattgaa ctctcgccgg aaagctcaat
    15661 aagacaggtt ctacgtttag ttgccgcgct tttatatgcg cttgatttac aacatcttct
    15721 ggataatttt taccagaaaa atcactaatt ctttcgttgc tccagacgac gcagagaacg
    15781 ctcacggcgg ctctcttcac gacttctgtc gagcaaaatt tcttcgataa aggccagatg
    15841 gcgatgcgat gcttcgcgcg cttcttccgg cttaccggcc ataatcgctt caaatatgcg
    15901 ggtgcggtga ctactcacca gcggcagcat ctcgcgacgc gaatagagca attcgaagtt
    15961 ctggcggaca ttctgggcca acatcggctc catacacctt agcagatgaa gcagaaccac
    16021 attgtgggcc gcttcggtga cggcaatctg atactggagt acggcgtttg attccgcgtc
    16081 cagatcgcca gactgctgcg ccagctctat ggcgtggtgg agttcacgga tgcgttcctt
    16141 gtcttcatcg gtactacgca gcgcggcgta ataagcggcg ataccttcca gggcgtgtcg
    16201 tgtttcgagc aagtcatact gtgactcagg atggtcggag agcagctcca ccagcggatc
    16261 gctgaagctt tgccataggc tgctctggac aaaagtgccg ccaccctggc gacgaagcaa
    16321 caagcccttc gcttcgagac gttgaatcgc ctcacgcaag gagggacggg agacgtcaaa
    16381 ctgttttgcc agttcgcgtt ccggtgggag tttttcgccc gggcggagag tgccttcgag
    16441 gatcaaaaac tccagttgct gctcaatcac atcggagagt tttggttggc ggattttgct
    16501 gtaggccatg agttcctgtc ttaagccact tgccgaagtc aattggtctt accaatttca
    16561 tgtctgtgac gctaaagtaa caaagtattc accttatgtc catacaggtt ttgattgaaa
    16621 tcatgaaact gtgcacattt taacaacttg acatatataa cgtttcaaag ttgtaactat
    16681 gcacaaatgt agactttacg taggaaagga gttttttaac gattattaaa ctataaaaat
    16741 ccgaattgaa ccgattcact taccaatttt gtgattttta attcaattaa a
//
LOCUS       DAPGUL010000101        16650 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.103, whole genome shotgun sequence.
ACCESSION   DAPGUL010000101 DAPGUL010000000
VERSION     DAPGUL010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16650
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.103"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(303..1334)
                     /gene="rsmC"
                     /locus_tag="RHX21_003470"
     CDS             complement(303..1334)
                     /gene="rsmC"
                     /locus_tag="RHX21_003470"
                     /EC_number="2.1.1.172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1207)-N(2))-methyltransferase
                     RsmC"
                     /protein_id="HDV1988614.1"
                     /translation="MSAFTPASEVLLRHSDDFEQSRILFAGDLQDDLPARLDTAASRA
                     HTQQFHHWQVLSRQMGDNARFSLVATADDVADCDTLIYYWPKNKPEAQFQLMNLLSLL
                     PVGTDIFVVGENRSGVRSAEQMLADYAPLNKVDSARRCGLYFGRLEKQPVFDADKFWG
                     EYSVDGLTVKTLPGVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGCGAGVLSVAFARHS
                     PKIRLTLCDVSAPAVEASRATLAANCVEGEVFASNVFSEVKGRFDMIISNPPFHDGMQ
                     TSLDAAQTLIRGAVRHLNSGGELRIVANAFLPYPDVLDETFGFHEVIAQTGRFKVYRA
                     IMTRQAKKG"
     gene            1437..1850
                     /gene="holD"
                     /locus_tag="RHX21_003471"
     CDS             1437..1850
                     /gene="holD"
                     /locus_tag="RHX21_003471"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit psi"
                     /protein_id="HDV1988615.1"
                     /translation="MTSRRDWQLQQLGITQWSLRRPGALQGEIAIAIPAHVRLVMVAN
                     DLPALTDPLVSDVLRALTVSPDQVLQLTPEKIAMLPQGSRCNSWRLGTDEPLSLEGAQ
                     VASPALTELRANPTARAALWQQICTYEHDFFPRND"
     gene            1819..2265
                     /gene="rimI"
                     /locus_tag="RHX21_003472"
     CDS             1819..2265
                     /gene="rimI"
                     /locus_tag="RHX21_003472"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDV1988616.1"
                     /translation="MNTISSLETTDLPAAYHIEQRAHAFPWSEKTFASNQGERYLNFQ
                     LTQNGKMAAFAITQVVLDEATLFNIAVDPDYQRQGLGRVLLEHLIDELEKRGVATLWL
                     EVRASNAAAIALYESLGFNEATIRRNYYPTTDGREDAIIMALPISM"
     gene            2280..2957
                     /gene="yjjG"
                     /locus_tag="RHX21_003473"
     CDS             2280..2957
                     /gene="yjjG"
                     /locus_tag="RHX21_003473"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine 5'-nucleotidase"
                     /protein_id="HDV1988617.1"
                     /translation="MKWDWIFFDADETLFTFDSFTGLQRMFLDYSVTFTAEDFQDYQA
                     VNKPLWVDYQNGAITSLQLQHGRFESWAERLKVEAGLLNDAFINAMAEICTPLPGAVS
                     LLNAIRGNAKIGIITNGFSALQQVRLERTGLRDYFDLLVISEEVGVAKPNKKIFDYAL
                     EQAGNPDRSRVLMVGDTAESDILGGINAGLATCWLNAHHREQPEGIAPTWTVSSLHEL
                     EQLLCKH"
     gene            3343..4566
                     /locus_tag="RHX21_003474"
     CDS             3343..4566
                     /locus_tag="RHX21_003474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001402824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDV1988618.1"
                     /translation="MALSDAWLRSVVGKERDKVLVKSDRDGLSVRVSPKGRVVFQYRY
                     QWAGKGERLDIGTYPATGLKEAREEVIRLRGELESNRNPRFVKQAEKRKATEAMTVES
                     VIRAWYEAYCVKNKKGSEQILRSFELHLFSKIGNIPHDAATLHDWLEVLEPLSTKTPA
                     IADRLLINAKQAHVWAYKRKLIETRPLSDITGKDMDIRKGQKKRFLTHDEIKILYAAI
                     DGSRMVPKYRAFIKLLLHFGCRSSELITARVDDFDFINKVWTVPPERHKTGEITGEPL
                     KRPIIEPVEELIKNAISMNNGSDMLFTKEGSREPVGRTSLQSLPYNLMQYAWRSLGYQ
                     FPHWSLHDLRRTARTNFSDLTAPHIAEIMLGHKLPGVWQVYDKSDYLEEQRKAYQAWW
                     ERVESIITCASSDPN"
     gene            4721..5536
                     /locus_tag="RHX21_003475"
     CDS             4721..5536
                     /locus_tag="RHX21_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016570101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988619.1"
                     /translation="MQSEIITQKNGKGIFDRKAWLTESKKLYLSAKLLRSEGERNKKL
                     LRAASKKSPIVHEYIDIASATDQTSRLMLGYAFEMLLKSAILLMNLGARKKAIENEFC
                     NYGHKLDCMAVDLGLPLTVDELKLLKVASRDIVLNARYPIGIVDDNKYITELNERNIQ
                     LADENIFRDMVSLYDKIKSIVAKFDNDVANCANFNMLRLSEFTLFMRNGGGLSSRAIV
                     IFSDKFPEVSKRKSYLKKAIEEHAGKVAFLYTYRWSSFSFFEDTGKKLIPLVE"
     gene            complement(5866..6477)
                     /locus_tag="RHX21_003476"
     CDS             complement(5866..6477)
                     /locus_tag="RHX21_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF551 domain-containing protein"
                     /protein_id="HDV1988620.1"
                     /translation="MTTFTDKELIKEIKERIGSLDVRDNVERRAYEIALASLEAEPVA
                     WLHSDNGLGIPAITRSKNIADSWLSKGWYVQPLYMAQPVSVVPDALPSLNNGIVGFDE
                     GWNACRAVMLHGAEPVSQTYKLNKLSGNPPVTPDGWISCSERMPEDGQHVIILCDGAF
                     VLYAQYRDGEFFDVVRNGEEFFETQSRNVTHWIPLPEPPQEVN"
     gene            complement(6477..6839)
                     /locus_tag="RHX21_003477"
     CDS             complement(6477..6839)
                     /locus_tag="RHX21_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988621.1"
                     /translation="MRMNVFEMEGFLRGRCVPRDLKVNETDAEYLVRKFDALEAKCAA
                     QENKVIPVSTELPPANESVLLFDANGEGWLIGWRSLWYTWGQKETGEWQWTFQVGDLE
                     NVNITHWAVMPKAPEAGA"
     gene            complement(6830..7366)
                     /gene="yfdR"
                     /locus_tag="RHX21_003478"
     CDS             complement(6830..7366)
                     /gene="yfdR"
                     /locus_tag="RHX21_003478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416862.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-deoxynucleotidase"
                     /protein_id="HDV1988622.1"
                     /translation="MSFIKTFSGKHFYYDRINKDDIDINDIAVSLSNICRFAGHLSHF
                     YSVAQHAVLCSQLVPQEFAFEALMHDATEAYCLDIPAPLKRLLPDYKQMEEKIDAVIR
                     EKYGLPPVMSTPVKYADLIMLATERRDLGLDDGSFWPVLKGIPATEMFNVIPLAPGHA
                     YGMFMERFNELSELRKCA"
     gene            complement(7494..8318)
                     /locus_tag="RHX21_003479"
     CDS             complement(7494..8318)
                     /locus_tag="RHX21_003479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2303 family protein"
                     /protein_id="HDV1988623.1"
                     /translation="MSQNLDATAINQIHALISAQGVNEIISKIGADAVALPENFRIHD
                     LEKFNLNRFRFRGALSTASIDDFTRYSKDLADEGTRCFIDADNMRAVSVLNLGTIDEP
                     GHADNTATLKLKKTAPFSALLSVNGERNSQKSLAEWIEDWADYLVGFDANGDAIQATK
                     AAAAVRKITIEANQTADFEDNDFSGKRSLMESVEAKTKDIMPVAFEFKCVPFEGLKER
                     PFKLRLSIITGDRPVLVLRIIQLEAVQEEMANEFRNLLVEKFKDSKVETFIGTFTA"
     gene            complement(8384..8746)
                     /locus_tag="RHX21_003480"
     CDS             complement(8384..8746)
                     /locus_tag="RHX21_003480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416860.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988624.1"
                     /translation="MASERSTDVQAFIGELDGGVFETKIGAVLSEVASGVMNTKTKGK
                     VSLNLEIEPFDENRVKIKHKLSYVRPTNRGKISEEDTTETPMYVNRGGRLTILQEDQG
                     QLLTLAGEPDGKLRAAGH"
     gene            complement(9449..10141)
                     /locus_tag="RHX21_003481"
     CDS             complement(9449..10141)
                     /locus_tag="RHX21_003481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001358750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDV1988625.1"
                     /translation="MNIGNRVRQLRQAKNMKIADLAEAIGVDAANISRLETGKQKQFT
                     EQALSNIARSLGVDIADLFTSDVKSNTVCKNSISEDVAQVKDVFRIEMLDVSASAGNG
                     LIQGGDVIDVIHAIEYRTDNAVSMFGGRPANHIKVINVRGDSMCPTIEPGDLIFVDVS
                     INQFDGDGIYVFGFDDKIYVKRLQMIPDKLLVISDNQIYREWGITSENEHRFMVFGKV
                     LISQSQTLKRHN"
     gene            10239..10499
                     /locus_tag="RHX21_003482"
     CDS             10239..10499
                     /locus_tag="RHX21_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001191680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDV1988626.1"
                     /translation="MQSPLRNVRKAHGFTLQHVAAGVQVNPATLSRIERLEQIPSIDL
                     AERLANFFKGEISEMQILYPARFQSSQNQNGFKPQEQEVSRG"
     gene            10492..11049
                     /gene="ymfL"
                     /locus_tag="RHX21_003483"
     CDS             10492..11049
                     /gene="ymfL"
                     /locus_tag="RHX21_003483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415665.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YmfL"
                     /protein_id="HDV1988627.1"
                     /translation="MGNHHWKVEKQPEWYVKAVRKTIAALPGGYAEAAEWLDVTENAL
                     FNRLRADGDQIFPLGWAMILQRAGGTHFIADAVAQSANGVFVSLPDVEDVDNADINQR
                     LLEVIEQIGSYSKQIRSAIEDGVVEPHEKTAINDELYLSISKLQEHAALVYKIFCVSE
                     SNDARECAAPGVVASIASGCGETNA"
     gene            11225..11404
                     /locus_tag="RHX21_003484"
     CDS             11225..11404
                     /locus_tag="RHX21_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001761574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4222 domain-containing protein"
                     /protein_id="HDV1988628.1"
                     /translation="MRQVNRWFKDHYGVPVRVIRWEPETQRVIYLREGYEHECFSPLE
                     QFRRKFREIEVGHEH"
     gene            11394..12335
                     /locus_tag="RHX21_003485"
     CDS             11394..12335
                     /locus_tag="RHX21_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000104949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDV1988629.1"
                     /translation="MSTKLTGYVWDGCAASGMKLSSVAIMARLADFSNDEGVCWPSIE
                     TIARQIGAGMSTVRTAIARLEAEGWLTRKARRQGNRNASNVYQLNVAKLQAAAFSQLS
                     DSDPSKSDASKSDTSKFDASKSGKKAGFHPSESGGDPSVKSKHDPSDKKPSRPDASQP
                     DTQTAEQDFLTRHPDAVVFSPKKRQWGTQDDLTCAQWLWKKIIALYEQAAECDGEVVR
                     PKEPNWTAWANEIRLMCVQDGRTHKQICEMYSRVSRDPFWCRNVLSPSKLREKWDELS
                     LRLSPSISTYTEKREDPYFKSSYDSVDYSQIPAGFRG"
     gene            12338..12667
                     /locus_tag="RHX21_003486"
     CDS             12338..12667
                     /locus_tag="RHX21_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988630.1"
                     /translation="MSLLNEVQKFIEAHPGCTSGDIADAFAGYSRQRVLQSASKLRQS
                     GRVAHRCEGDTRRHFPRLTERAQEPEPQPVRETRPVRNFYVGTNDSRVILCLTRQAEK
                     LVREMAA"
     gene            12664..12990
                     /locus_tag="RHX21_003487"
     CDS             12664..12990
                     /locus_tag="RHX21_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003878599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HDV1988631.1"
                     /translation="MTTLTQCQQQVLDMLISYQKERGFPPTNQEVATMLGYRSVNAAV
                     EHLRALEKKGVITIKRGVARGITLHTAVKDDDSEAVGIIRALLAGEENARLRAAHWLH
                     ERGLKV"
     gene            12987..13376
                     /locus_tag="RHX21_003488"
     CDS             12987..13376
                     /locus_tag="RHX21_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDV1988632.1"
                     /translation="MKLILPFPPSVNTYWRHPNKGAFAGKSLISEAGRKFQSAACAAI
                     VEQLRRLPKPTSAPASVEIVLFPPDNRIRDLDNYNKALFDALTHAGVWEDDRQVKRML
                     VEWGPVIPKGKVEITISKYEKPAGAAA"
     gene            13396..14205
                     /locus_tag="RHX21_003489"
     CDS             13396..14205
                     /locus_tag="RHX21_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KilA-N domain-containing protein"
                     /protein_id="HDV1988633.1"
                     /translation="MNNLMVIDGIEVHRDAYGRYSLNDLHRAAVASGANARTKEPGKF
                     LSSQQTVELVHELTNTQNLGVDPVSVIHGGNERGTYVCKELVYAYAMWISPSFHLKVI
                     RTFDMVTSAPEKLSGQAADKMQAGVILLDFMRRELNLSNSSVLGACQKLQEAVGLPNL
                     APRYAIDAPADAPDGSSRPTLSLSALLKQYGIRLTANQAYHQMAKLGIVEQRERYSRT
                     AINNIKKFWSLTAKGCMFGKNITSPANPRETQPHFFESRFPELLKLLDTVH"
     gene            14213..15202
                     /locus_tag="RHX21_003490"
     CDS             14213..15202
                     /locus_tag="RHX21_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001764249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF968 domain-containing protein"
                     /protein_id="HDV1988634.1"
                     /translation="MRALLTPEIAPRMGIVLFRPGSELMPLFMQGRVLLEPEPEHYSS
                     FASGAVPAASQPLADDPAVWAVFRNEAVIRRAGGVECLESWLLREKGCQWPHSDWHSE
                     NMTTMRHAPGAIRLCWHCDNQLRDQFTERLESMATDNCARWVLSVVRRDLGFDDSHVV
                     TMPELCWWLIRNDLADALPESAARKALRLPKPVVPSVTRESDLVPSVPATSIIQDKAK
                     KVLALKVDPESPESFMLRPKRRRWVNEKYTRWVKTQPCACCGKPADDPHHLIGHGQGG
                     MGTKAHDLFVLPLCRKHHDELHADTVAFEEMYGSQLELIFRFIDRALAIGVLA"
     gene            15220..15573
                     /locus_tag="RHX21_003491"
     CDS             15220..15573
                     /locus_tag="RHX21_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001564334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein"
                     /protein_id="HDV1988635.1"
                     /translation="MRDMYEVLDRWGAWAAAENSGVDWQPVAAGFKRLLPHGRKSRIQ
                     CDDDEGIIIDGCVARLRKYKPAEYELIIAHFVVGISLRTIAKKRKCSDGTVRKDMQTA
                     MGFIDGCLSFFYLIQ"
     gene            15653..>16650
                     /locus_tag="RHX21_003492"
     CDS             15653..>16650
                     /locus_tag="RHX21_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020803204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HDV1988636.1"
                     /translation="MNIQAVDIFCGAGGLTFGLKKAGIEVSHGIDIDESCRFAIESNN
                     PLTKFINQSVTELQSSDVSAMFKEGNIRLLAGCAPCQPFSKYRNPNSRKDDTKWRLLS
                     EFQRIVSDVMPELVTMENVPQLRNHKVFEEFVSVLKTLGYHLWYDVVKCSEYGLPQNR
                     RRLILIGSILGPISLDQKKVSRKVTVKDAIGQLPKIGAGEKLESDPLHRSPKLRDINL
                     KRILHSLPGGTWDDWPEEIRADCHKKHSGATYKSVYGRMVWDDTSPTITTQCYGYGNG
                     RFGHPEQNRAITLREAAILQSFPMDYKFIGKNTPFSFQKLGTMIGNAVPPIIGQVIG"
BASE COUNT         4297 a         3823 c         4207 g         4323 t
ORIGIN      
        1 gaagctagcg cgtctaccaa ttccgccacc ttcgcatacc atcaattctt aaaaagaatt
       61 gctaccacgg aggcgcattc tagtggtttt cagcttttcg tcaatagtta attatcgccg
      121 gaggtgtaat tgctggaaaa atgtccatca ggaaactagc gtgcaggttt ggtaggcatg
      181 cgggggcaga tgccagatgc gacgctggcg cgtcttatct ggcctacgaa gggctaacgt
      241 gcaggttttg taggtcggat aaggcgttca cgccgcatcc gacacggtat tcggcgagat
      301 aattaacctt tcttcgcctg gcgggtcata atggcgcgat acaccttgaa acgcccggtt
      361 tgcgcaatca cttcatggaa gccaaatgtc tcatccagca cgtccgggta aggcaggaag
      421 gcgttcgcta caattcgcag ctcgccgccg ctattaagat gacgcaccgc gccgcgaatc
      481 agcgtttgcg ccgcatccag gctggtttgc atcccatcgt ggaacggcgg gttggagatg
      541 atcatatcaa aacgaccttt cacctcggaa aagacgttgc tggcaaagac ttcaccttca
      601 acacagttgg ccgcaagtgt tgcgcggctg gcttctaccg ctggcgcaga gacatcgcac
      661 aaggtgagac gaattttcgg cgaatggcgc gcaaaggcaa ctgaaagcac ccccgcgcca
      721 cagccgacat ccagcacttt acctttcgtg tgcggagtta acgtcgagag cagcaactgg
      781 ctaccgacat ccagaccgtc gcggctaaac acgccaggca gcgttttgac cgtcaggcca
      841 tcgacgctgt attcgcccca gaatttatcg gcatcaaata ccggctgttt ttccagacga
      901 ccaaaataga ggccacagcg acgagcgctg tcgactttat tcaacggcgc ataatctgcc
      961 agcatctgct cggcgctgcg cacgccgctg cggttctcgc caacgacaaa aatatccgtc
     1021 cccaccggca gcagagaaag taaattcatc aactggaact gggcttccgg tttgttcttc
     1081 ggccagtagt aaatcagcgt atcgcaatct gcgacgtcat ccgccgtggc gaccagactg
     1141 aaacgggcgt tatcccccat ctggcggctt aatacctgcc agtggtggaa ttgctgggta
     1201 tgagcacggc tggccgcggt atctaaacgc gcgggcaggt catcctgtaa gtctccggca
     1261 aacagaatac ggctttgttc gaaatcatca ctgtgacgca gcaagacttc acttgccggg
     1321 gtaaatgcag acatggaatg ctcctcaatt gatactggcg gcgattatag ccatatgttg
     1381 gcgcggtatc gacgaatttg ctatatttgc gcccctgaca acaggagcga ttcgctatga
     1441 catcccgacg agactggcag ttacagcaac tgggcattac ccagtggtcg ctgcgtcgcc
     1501 ctggcgcgtt gcagggggag attgccattg cgatcccggc acacgtccgt ctggtgatgg
     1561 tggcaaacga tcttcccgcc ctgaccgatc ctttagtgag cgatgttctg cgcgcattaa
     1621 ccgtcagccc cgatcaagtg ctgcaactga cgccagaaaa aatcgcgatg ctgccgcaag
     1681 gcagtcgctg caacagctgg cggttgggta ctgacgaacc gctatcactg gaaggcgctc
     1741 aggtggcatc accggcgctc accgaattac gggcaaaccc aacggcacgc gccgcgttat
     1801 ggcaacaaat ttgcacatat gaacacgatt tcttccctcg aaacgactga tttaccagcg
     1861 gcttaccaca ttgaacaacg cgcccacgcc tttccgtgga gtgaaaaaac ctttgccagc
     1921 aaccagggcg agcgttatct caactttcag ttaacgcaaa acggcaaaat ggcggcgttt
     1981 gcgattacgc aagtggtgct ggatgaagct acattgttca atattgcggt cgatcctgac
     2041 tatcagcgtc agggattggg aagggtgctg ctggaacatc tgatcgacga actggaaaaa
     2101 cgcggcgtgg cgacactatg gctggaagtc cgtgcctcaa atgctgccgc cattgccctg
     2161 tacgaaagtt taggctttaa cgaggcgacg attcgccgca attactaccc caccacggac
     2221 ggtcgcgaag acgccatcat catggcgttg ccaatcagta tgtaagacaa ggtggaataa
     2281 tgaagtggga ctggattttc tttgatgccg atgaaacgct gtttaccttt gactcattca
     2341 ccggcctgca gcggatgttt cttgattaca gcgtcacctt taccgctgaa gattttcagg
     2401 actatcaggc cgttaacaag ccactgtggg tggattatca aaacggcgcg atcacttcat
     2461 tacagcttca gcacgggcgt tttgagagct gggccgaacg gctgaaagtt gaagcaggct
     2521 tgcttaacga tgcctttatt aatgcgatgg cggaaatctg cacgccgctg ccgggcgcgg
     2581 tttctctgct taacgccatt cgtggcaacg ccaaaatcgg catcatcacc aacggcttta
     2641 gcgccttgca gcaagtgcgt ctggaacgca cgggcctgcg tgattacttc gatttgctgg
     2701 tgatttccga agaagttggc gttgccaaac cgaataagaa aattttcgat tatgcgctgg
     2761 aacaggcggg caatcctgac cgttcacgcg tgctgatggt tggcgacact gccgagtccg
     2821 atattctcgg tggcatcaac gccgggcttg cgacctgctg gctgaatgcg caccatcgcg
     2881 agcaaccaga aggcatcgcg cccacctgga ccgtttcttc gttgcacgaa ctggagcagc
     2941 tcctgtgtaa acactgattg cctccccccc gttgatgggt aaaatagccg caatttttcg
     3001 ttttcaacaa gcgcggcgcg atgccgctta ctcaagaaga aagaattatg acgttgtctc
     3061 cttatttgca agaggtggcg aagcgccgca cttttgccat tatttctcac cccaataatt
     3121 aagcccaatt taaagctctt ttattctttc aaaatccttt cagttaattg aggttgagtc
     3181 atataactca tttaaataca tttggttatg tggcttcttt aattgaaaat tctttcatgt
     3241 agctttaaat cgatcaggtt gctttcatca aaaatctgta catatgcttg tacataatgt
     3301 acaaagcagc agaggtgttt tgcgatttgt acaaggtgag taatggcgct gtctgatgcg
     3361 tggttgcgtt cagtcgttgg aaaggaacgt gataaggttt tggttaaatc cgatcgtgat
     3421 ggtctgtctg tcagagtatc accgaaaggt cgcgtagtgt tccaatatcg ttatcaatgg
     3481 gcagggaaag gtgagcgtct tgatatcgga acttacccgg caactggatt aaaagaggcc
     3541 agagaagaag ttattcgtct ccgtggtgaa cttgagtcaa accgtaatcc acgatttgtc
     3601 aagcaggctg aaaaacgaaa agctactgaa gccatgacgg tagagtctgt gatccgtgcc
     3661 tggtatgaag catattgtgt aaaaaataaa aaaggttctg aacagatact ccgctcgttt
     3721 gagctgcacc tgttctctaa aatcgggaat atccctcacg atgcagctac attgcatgat
     3781 tggttagaag tcctggagcc tcttagcact aagactccag caatagcaga ccgattgcta
     3841 attaacgcaa agcaggccca tgtctgggcg tataagagaa agctcattga aactcgcccg
     3901 ctgtcggata tcacgggtaa agatatggat atccgtaaag gtcagaagaa acggtttctg
     3961 acacatgatg aaattaaaat cctttatgct gcgatcgatg gttctcgaat ggttcctaaa
     4021 taccgggcct tcattaagct attgctgcat tttggctgcc gtagttcaga gctaattact
     4081 gccagggtgg acgattttga tttcattaat aaggtatgga ctgtaccacc agaacgacat
     4141 aagactgggg agataacagg cgaaccgcta aagaggccca ttattgaacc ggtggaggag
     4201 cttataaaga acgctatctc tatgaacaat ggttccgata tgctttttac taaggaagga
     4261 agcagggaac ccgttggtcg aacatcattg cagtcgctgc cttacaattt aatgcagtac
     4321 gcatggcgga gtttggggta tcaattccct cattggtctc ttcatgattt gaggcgaaca
     4381 gcacgaacaa acttttctga tcttactgct cctcatattg cagaaataat gctcggccat
     4441 aaactgccag gggtttggca ggtttatgac aagagcgatt atctagaaga acagcgtaaa
     4501 gcctaccagg cgtggtggga gagggttgaa tcgatcatta cttgtgctag ctcagacccc
     4561 aactgatagt ctgttttgtc ggaatactta caatttctca ttcaagttag ttaagtggta
     4621 ttttacaaat ggagacaatg taatgtctgg tcaaaataac agcgacgaga tttgcaattg
     4681 attagtggca ggtttggttc taataacata ggagttattg atgcagagcg agataatcac
     4741 gcagaaaaat gggaaaggta tatttgatcg aaaggcttgg ttaacagagt ctaaaaaact
     4801 gtatttatct gcgaagctgt tgagaagtga aggtgagcga aacaaaaaat tgcttcgggc
     4861 agcaagtaag aaatctccta ttgttcatga atacatcgat atcgcatcgg caactgatca
     4921 aactagcaga cttatgttgg ggtatgcttt tgaaatgttg ttaaagtcag cgattcttct
     4981 aatgaatctc ggtgcgagaa aaaaagctat tgaaaatgag ttttgtaatt atgggcataa
     5041 acttgattgt atggctgttg atttaggttt gccattaacc gttgacgaac tgaagttatt
     5101 gaaagttgcg tctcgagata tagttttaaa tgctcgatat cctattggaa tagtggatga
     5161 taataaatat ataacagagt tgaatgaaag aaatattcag ttggcagatg aaaatatttt
     5221 tagggatatg gtcagtctgt atgacaaaat aaaaagtata gttgctaagt ttgataatga
     5281 tgtagcgaat tgtgcaaatt tcaatatgct tagattgagt gagtttactc tctttatgcg
     5341 gaatggtggt ggactatcat caagagcaat agttatcttt tcggataaat ttccagaagt
     5401 cagtaaacgc aagtcatatt taaaaaaagc tatcgaagaa catgcaggca aagtggcttt
     5461 tttatatact taccgctggt cttcgttttc attctttgaa gacacaggta aaaaacttat
     5521 cccgcttgtg gagtagtaca gatgagctgt gtcccgttga ttattttata cttatgttag
     5581 tagtatcttc ttttggcaca gagcaggtag ttagattagg tttgactctg tgccatagtg
     5641 gtgtgtcagc ttacatctga tctaaggcat attactcaat gactcctgca aacctgtaaa
     5701 tcttttgtga tgcccattta tttgggcagg atttaatatc aggatctgga aagtctggtc
     5761 tgtatttctt gccagttctc cggtttacgc tgttccagcg aagcaccgtc gatattgaaa
     5821 cgccacagaa ttcggcgact tgttttgttg tcattaagtt gttcattaat ttacctcctg
     5881 cggcggctcc ggtagcggta tccagtgggt tacattgcgg ctctgcgttt cgaagaactc
     5941 ctcaccattg cggacaacat caaaaaactc accgtctcga tattgcgcat aaagaacgaa
     6001 tgcgccatca cataaaataa ttacgtgctg accgtcctct ggcattcgct cactacagct
     6061 tatccaacca tccggagtta caggagggtt gcccgacagc ttgttcaact tgtaagtctg
     6121 gcttacaggt tcggcaccat gaagcatgac ggcgcggcag gcgttccagc cttcatcaaa
     6181 gccgactatg ccattattta aagacggaag agcatccggc accaccgaca ctggctgagc
     6241 catatatagc ggctgaacat accagccctt tgataaccaa ctgtcagcaa tgtttttgct
     6301 cctggttatt gccggaatac ctaagccatt gtctgaatga agccacgcca ccggctctgc
     6361 ttccagtgat gccagagcaa tttcataagc acggcgctca acattgtctc gcacgtctaa
     6421 gctgccgatt cgttctttga tttctttaat cagttcctta tcggtgaaag tggtcattat
     6481 gctccagcct ccggtgcttt tggcattact gcccagtgag tgatattgac gttttcaagg
     6541 tccccgacct gaaatgtcca ctgccattct ccggtttctt tttgtcccca ggtgtaccag
     6601 agagaacgcc agccaattag ccagccttct ccgttagcat cgaataacaa aacactttca
     6661 tttgctggtg gcagttcagt tgacactggt attactttgt tttcctgtgc tgcacattta
     6721 gcttcaagcg catcgaattt acgcaccagg tattcagcat ctgtttcatt tactttcaga
     6781 tctcgcggta cacatctccc acgaagaaac ccttccattt cgaaaacatt catgcgcatt
     6841 tgcgtaactc cgataactcg ttaaagcgtt ccataaacat cccgtaggca tggcccggtg
     6901 ccagtggaat cacgttgaac atctctgttg ccgggatacc tttcagtaca ggccagaaag
     6961 agccatcatc aagcccgaga tcgcggcgtt cggttgccag catgatgaga tcggcatatt
     7021 tcacgggcgt actcataact gggggtaacc cgtatttctc acggattacg gcgtctattt
     7081 tttcttccat ttgtttatag tcaggaagaa ggcgtttcag tggtgcggga atgtccaggc
     7141 aatacgcttc tgttgcatca tgcattaacg cttcaaaagc aaattcctgc ggcaccaact
     7201 ggctgcaaag aaccgcatgt tgggcgacgc tgtagaagtg cgaaagatga ccggcaaagc
     7261 gacagatatt tgaaagggaa accgcgatat cgttaatatc gatgtcgtct ttatttatcc
     7321 tgtcataata aaaatgcttc ccggaaaaag ttttaataaa tgacattttg ttctccacgt
     7381 atatgcgctg caccgcgctg aattttggtt aaagaaaacc ctcgccatca ggcgattatt
     7441 gagttaatta cgtttccata aatgcccccg caggggcatt tgcagtaatg aaatcaggcg
     7501 gtgaaagtac caataaaggt ttctactttg ctgtctttga atttttcaac aagcagatta
     7561 cgaaattcgt tagccatttc ttcctgtact gcttccagct gaataatgcg cagaaccagt
     7621 acagggcgat caccagtgat aatgctgagg cgtaatttaa acggacgttc tttcaggcct
     7681 tcaaacggaa cgcatttaaa ctcaaatgct actggcataa tgtctttggt tttcgcttcg
     7741 acagactcca tcagagagcg tttgccgctg aagtcattgt cttcaaaatc agcggtctgg
     7801 tttgcttcaa tcgtgatttt acggaccgcc gcagccgctt ttgttgcctg aatggcgtca
     7861 ccattagcat caaagcccac aaggtagtcg gcccagtctt caatccattc tgccagtgac
     7921 ttctgggagt tacgctcgcc gttaacagac aacagagcag agaacggtgc tgtctttttc
     7981 agtttgagag tggcggtgtt atctgcgtga cctggttcat caatagtacc caggttaagc
     8041 acactgacgg ctcgcatatt atcagcatcg ataaagcagc gggtgccttc atctgcaaga
     8101 tctttagaat aacgggtaaa gtcatcgatg ctggcagtgg aaagcgcacc acggaaacgg
     8161 aagcgattta aattaaattt ttccagatca tgaatgcgga aattctcagg caatgccaca
     8221 gcatcggcac caatcttact gataatttca ttaacaccct gagcagaaat aagggcatgg
     8281 atttgattaa ttgcggttgc gtctaagttc tgagacataa taagtcctca ctatataaag
     8341 atattcagtg atgagataaa taatcagtta attaagaacg atattaatga cctgctgcgc
     8401 ggagttttcc gtcaggttca ccggcaagag tcagtaattg tccctggtct tcctgcagaa
     8461 tagtcaggcg accaccgcga ttgacataca tcggcgtttc ggtggtgtct tcttcggaaa
     8521 ttttcccgcg gttagtcggg cgaacatatg agagtttgtg tttgattttc acacggttct
     8581 catcaaatgg ttcgatttcc aggttgagtg agaccttacc tttggttttc gtgttcatca
     8641 caccggaagc gacttcactg agaactgcgc cgattttggt ttcaaatacg ccgccgtcca
     8701 gctccccgat aaatgcctgc acatcagtac tgcgttcgct agccattttg ctgctcctca
     8761 tcatatcgac cctgtaaggt cggttagttt ctccacaaaa cagagaagaa cacctgcggt
     8821 ggcagccgcc cggatggatt gggttatgag cccgtcgtcc ggtgatgctc ttctctgttt
     8881 tgtaaaaaga gcggtaccag ccggaagcaa gggtacaaac tggtaccgcc aaagcagtgg
     8941 ctgttgtggt ggggttgtca ctcaggcgta tggtcaacct gacaatccgg tgtcctcaac
     9001 ggggaaagag taaccccgcc atacttaccg ccgcgccatt tcgcggatta ccacaacgct
     9061 gagagcactt agccagttac ggcaccacac tttgtcgcgg ctccataaat gccctcatcg
     9121 ttgcaccctg gtctcttccc aggcgtcaaa ccgaatcgcc acgctggtta ggcgtcttat
     9181 cagcatcatc attgacttgc acattccggc tacctggttt gtttgcccga gcaaggagtg
     9241 gattgtcccc tttaacgtcc ccagaccgct aacgacgcat gtgccatacg ccgtgttaca
     9301 accaaatttt gttagtacct tgtttgtttg tctggaaaga aagataaaat gaagttgcgc
     9361 attatgcaag tgtttttgtt gcgagatatg caatttaaag ggtaatgaaa agccaccttt
     9421 gggtggctaa ttgatgagga ggtaagggtt aattgtgtcg cttaagggtt tgtgactggc
     9481 tgattaagac ctttccaaag accataaacc ggtgttcatt ttcgctggta attccccatt
     9541 cacggtaaat ctggttatca gaaatcacca gtagtttgtc aggtatcatt tgcagtcgtt
     9601 tgacataaat tttatcatca aaaccaaata catagatacc atctccatca aactgattga
     9661 tactgacatc aacgaagatg agatctcctg gctcaatggt tggacacata ctgtccccac
     9721 gaacgttgat aactttaatg tgattggctg gccgtccgcc aaacatcgat acagcattat
     9781 cagttctgta ttcaatggca tgaatcacat caatgacatc accgccctgg ataaggccat
     9841 ttcccgcact ggcactgaca tccagcattt caatacggaa tacatccttc acctgcgcaa
     9901 catcctcact aatactgttt ttacatacag tattactttt gacgtctgag gtaaagagat
     9961 cagcaatatc aacacctaag ctcctggcaa tattactcag ggcttgttca gtgaattgtt
    10021 tctgcttacc tgtttccagg cgtgagatat tcgccgcatc cactcctatt gcttcagcga
    10081 gatcggcgat tttcatgttc ttcgcctggc gaagttgtct gactcggttt cctatgttca
    10141 tgcgtttatt acatttcttt attgcgcgtt aagcaaatca acttgcgcaa aatatttgcg
    10201 tgaaataata tgcttatcac gcaatatgtg gaggttatat gcaatcacca ttacggaatg
    10261 tgcgtaaggc gcacggattt actttgcagc atgttgctgc tggcgttcag gtcaatccag
    10321 cgacgctgag tcgtattgaa agactggaac aaattccatc tatcgatctt gcagaacgtc
    10381 tggccaattt ttttaagggt gaaatcagcg aaatgcagat tctttatccg gcacgttttc
    10441 aatctagcca aaaccagaat gggtttaaac cacaggaaca ggaggtaagc cgtgggtaat
    10501 catcactgga aagtggaaaa acagcctgag tggtacgtga aagctgtcag aaaaactatc
    10561 gcggcgttgc cggggggtta cgctgaagct gctgagtggc tggatgtaac agagaacgca
    10621 ttatttaacc gccttcgtgc cgatggcgat cagattttcc cgctgggatg ggcaatgatt
    10681 ttacaacgtg ctggtggcac tcacttcatt gccgacgctg tggcgcagtc tgcaaatggc
    10741 gtctttgtgt ctcttcctga cgtcgaggat gtggacaatg ccgatattaa ccagcgttta
    10801 ctggaagtca ttgaacagat cggcagttat tcaaaacaga ttcgttcggc aatcgaagac
    10861 ggtgtagtgg aaccgcatga gaagacagca attaacgacg agctgtacct ctcaatttcg
    10921 aagctgcagg agcatgcagc acttgtctac aaaatttttt gcgtttcaga aagtaatgac
    10981 gcccgcgagt gtgcagctcc gggcgtcgtg gcgtcgattg cttctggttg tggagaaact
    11041 aacgcatgaa cagtttaaca acacactacc gtcgctcgca actgattgcg cttcctgtac
    11101 cgggtggaaa agcgaaggtg gagtattgct atgcagtaaa tgtaccaggt gacagggaaa
    11161 ttgtaaccca cagctttgct gagtgggctg tgggggattt caaccggcag aaggagacag
    11221 tcctttgcga caagttaacc gctggttcaa agatcactac ggagtgcccg tcagagtcat
    11281 tcgttgggag ccggaaacac aacgggttat ctacctccgt gaaggctatg agcatgagtg
    11341 cttcagcccg ctcgaacagt ttcgtcgtaa attcagggaa atagaggtcg gtcatgagca
    11401 ctaaattaac cggctatgta tgggatggtt gcgctgcgtc aggcatgaaa ttatccagcg
    11461 tggcaattat ggcccgcctg gctgatttca gtaatgacga aggtgtgtgc tggccatcaa
    11521 ttgaaactat tgcccgtcag attggcgcgg ggatgagtac cgtcagaacg gctatcgcac
    11581 ggctggaagc agaaggctgg ttaacgcgta aggcgcgtcg ccagggtaac cgcaatgcgt
    11641 cgaatgttta tcagcttaac gttgcgaagc ttcaggcagc ggcattttct caactgtcag
    11701 attctgaccc gtcaaaatct gacgcatcaa aatctgacac gtcaaaattt gatgcgtcga
    11761 aatctggcaa aaaagcgggt tttcacccgt cagaatctgg cggggatccg tcagtaaaat
    11821 caaaacatga tccgtcagat aaaaaacctt ctcgtccgga cgcttcgcaa ccggacacgc
    11881 agacggctga acaggatttt ttaactcgcc atcctgatgc ggttgtattc agccctaaaa
    11941 agcgccagtg gggaacgcag gatgatttga cctgcgcaca gtggctctgg aaaaaaatca
    12001 ttgccctgta cgagcaggcc gccgaatgtg acggcgaggt ggttcgtccc aaagaaccga
    12061 actggacagc ctgggcaaac gaaattcgcc tgatgtgtgt gcaggatggt cgtactcaca
    12121 aacaaatctg cgagatgtac agccgcgtca gccgcgatcc gttctggtgc cgtaacgtgc
    12181 tcagcccgtc gaagctgcgg gaaaaatggg atgagctttc cctgcgctta tcgccgtcca
    12241 tcagcacata cacagaaaaa cgcgaagacc cgtatttcaa atccagttac gacagcgtgg
    12301 actacagcca gatcccggca ggattcaggg ggtgagcatg agtcttttga atgaagttca
    12361 gaaattcatt gaagcccatc cgggctgtac ttccggagac attgcggatg cttttgcagg
    12421 ttactcacgg cagcgcgttc tgcagtcagc aagcaagtta cgtcagagtg ggcgtgtggc
    12481 tcaccgttgt gaaggggata cacgcagaca tttcccgcgc ctgactgaga gagcgcagga
    12541 gccggaacca caaccagttc gtgaaaccag acctgtgcgc aatttctatg tcggcactaa
    12601 cgattcccgg gtgattttgt gcctgactcg ccaggcggaa aaactggtca gggagatggc
    12661 ggcatgacga cgttaactca atgccagcag caggtgctgg atatgctgat ttcttaccag
    12721 aaagaacgtg gcttcccgcc aaccaatcag gaggtggcaa ccatgctggg ataccgttca
    12781 gtgaatgcag cggtggagca tcttcgcgca ctggagaaaa aaggcgtcat cacgataaag
    12841 cgtggcgtgg cccgggggat cacgcttcat accgcagtga aggacgacga cagcgaagcg
    12901 gtcggtatca tccgcgcact gcttgccggt gaggagaacg ctaggttgcg tgcagcccac
    12961 tggttacatg agaggggcct gaaagtatga agttgatcct tcctttcccg cccagtgtga
    13021 acacgtactg gcgacacccc aacaaagggg catttgctgg taagagcctg ataagcgagg
    13081 cggggcgaaa atttcagagc gcggcgtgcg cagcaatagt tgagcagtta cgtcgtctgc
    13141 cgaaaccaac gtcggcacct gcttcagtgg agatcgtgtt gtttcctccg gataaccgga
    13201 tccgcgatct ggacaactat aacaaggctc tgtttgacgc cctgacccac gcgggtgtgt
    13261 gggaagacga cagacaggtg aaaagaatgc tggtggagtg gggaccggtt atcccgaaag
    13321 ggaaggtcga gatcactatc agtaagtatg agaaaccggc gggtgcagcc gcctgattaa
    13381 gaggagaaac gaagtatgaa taatctgatg gtcattgatg gtattgaagt tcatcgtgat
    13441 gcttatgggc gttacagcct gaacgatctg catcgcgcag cagtagcatc tggtgcaaat
    13501 gccagaacca aggagccagg aaagtttctt tccagccaac aaactgttga gcttgttcat
    13561 gaattgacca acacccagaa tttgggtgtt gacccggtga gtgtgattca tgggggaaat
    13621 gaacggggaa cgtatgtctg caaggaactg gtgtatgcct atgcaatgtg gatcagcccg
    13681 tcattccatc tgaaggtgat ccgtactttc gacatggtaa ccagcgcacc ggaaaaatta
    13741 tccggacagg ctgctgacaa gatgcaggct ggtgtgattc tgctggactt tatgcgccgg
    13801 gaattaaacc tgtctaactc ttcagtgctt ggtgcctgtc agaaactcca ggaggctgtt
    13861 ggcttaccga atctggcacc gcgctatgcc attgatgctc ctgctgacgc gcctgatggc
    13921 tcaagccgcc ccacgctgtc gctgagtgca ctgctgaaac agtatggtat ccgcctgacg
    13981 gctaatcagg catatcacca gatggcgaag ctggggatcg ttgaacaacg cgaacgatac
    14041 agccgtaccg cgattaacaa catcaaaaaa ttctggtcgc tgacagcgaa aggctgcatg
    14101 ttcggcaaga acatcaccag tcccgcaaat ccgcgcgaga cgcagccgca tttcttcgaa
    14161 tcccgattcc ctgagctgtt aaagctgctc gataccgttc attgaggtga ccgtgagagc
    14221 actactgacc cctgaaattg ccccgcgtat ggggatcgta ttgttcaggc ccggttcaga
    14281 gctgatgccc ctgtttatgc aggggcgtgt cctgctggag cctgagccgg agcattattc
    14341 atctttcgcc agtggtgccg ttcccgcggc gtcacaaccg ctggcggatg atcctgccgt
    14401 ttgggccgtg ttccgcaatg aggcagtgat ccgtcgtgct ggtggcgtgg aatgtcttga
    14461 aagctggtta cttcgtgaaa aaggctgcca gtggcctcat tccgactggc acagcgagaa
    14521 catgaccaca atgcgacacg ctccgggtgc aatccgtctg tgctggcact gcgataacca
    14581 gctgcgcgat cagttcacgg aacggctgga atcaatggca acggataact gtgcccgctg
    14641 ggtgttgtct gttgtgcgtc gggatctcgg ttttgatgac agtcacgttg tgacaatgcc
    14701 ggaactgtgc tggtggctga ttcgtaatga cctggcggat gccttaccgg aaagtgcagc
    14761 ccgtaaggca ctgagattac cgaagcctgt tgtgccgtct gtcacccggg aaagtgacct
    14821 tgtgccttcg gttcctgcta ccagcatcat ccaggataag gcgaaaaagg tgctggcgct
    14881 gaaagtggat ccggagtcgc cggagtcttt tatgttacgc ccaaaacgtc gccgctgggt
    14941 taatgaaaag tacacgcgct gggttaagac acagccgtgt gcatgttgtg gaaagcctgc
    15001 tgatgatccc caccacctga taggtcacgg tcagggtgga atgggtacaa aagcgcatga
    15061 cctctttgtg ttgcctttgt gcagaaagca tcacgacgag ctgcatgcag ataccgtggc
    15121 atttgaagag atgtatggct cccagctgga gctgatattt cgttttatcg atcgtgcgct
    15181 ggcaattggc gtgctggcct gattttgtgg agaaagttga tgcgtgatat gtatgaagtt
    15241 ttggaccgct ggggggcatg ggctgctgca gaaaacagtg gtgtggactg gcaaccggta
    15301 gctgctggct tcaagcggct tttacctcat ggcagaaagt cccggattca gtgcgatgat
    15361 gatgagggca tcataataga cggttgtgtc gctaggttgc gtaaatacaa gccggcagag
    15421 tatgagctga taattgctca ctttgttgtt ggcatttcgc tccgtacaat tgcaaagaag
    15481 cggaaatgtt cagacggaac agttcgaaaa gatatgcaaa cagctatggg gtttattgat
    15541 ggatgcttgt cattttttta tttaatacaa tgagttaagt gctatgtaaa atcattctac
    15601 tttcccaact tttatgtgta tataatacca gggtaaagta acggagaatc ttgtgaacat
    15661 tcaagcagta gacatttttt gtggcgcagg gggcttaact tttgggctaa aaaaagccgg
    15721 gattgaagtt tctcatggca ttgatattga tgagtcctgc cgtttcgcta ttgagagcaa
    15781 taatccctta acgaagttca ttaaccagtc agttactgaa ctgcaatcca gcgatgtgtc
    15841 tgctatgttc aaggaaggaa atattagatt acttgcaggc tgtgcccctt gccaaccgtt
    15901 ttccaagtat cgtaatccaa atagcagaaa agatgataca aagtggcgtc ttttatctga
    15961 gtttcagagg attgtaagtg atgtcatgcc agagcttgtg actatggaaa atgttcctca
    16021 acttagaaat cataaggttt ttgaagagtt tgttagtgta ttaaagactc ttgggtatca
    16081 tctgtggtac gacgttgtaa aatgttccga gtatggcttg cctcaaaata gacgtagatt
    16141 aattctaatt gggtccatat tggggccaat cagccttgat caaaaaaaag taagccgtaa
    16201 agttacagta aaggatgcta ttggtcagtt gccaaaaata ggtgcagggg agaaactcga
    16261 aagtgatcca ttgcatcgtt cgcctaaatt aagggatatt aaccttaaac gaatcttgca
    16321 ctctttacca ggtggtacgt gggatgattg gcctgaagaa attagagcgg attgccataa
    16381 aaagcattca ggtgctacct ataaaagtgt ttatggacgg atggtttggg acgatactag
    16441 tcctacaata actacccaat gttatggata tggtaatggg cgattcggac atcctgagca
    16501 aaatagagca ataactttgc gtgaagctgc tattttacaa tcttttccta tggattataa
    16561 atttattgga aaaaatacgc ctttttcatt ccaaaagtta ggaacgatga ttggtaatgc
    16621 tgttccccct ataattggcc aagtaatagg
//
LOCUS       DAPGUL010000102        16016 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.104, whole genome shotgun sequence.
ACCESSION   DAPGUL010000102 DAPGUL010000000
VERSION     DAPGUL010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16016
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.104"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(8..823)
                     /gene="djlA"
                     /locus_tag="RHX21_003493"
     CDS             complement(8..823)
                     /gene="djlA"
                     /locus_tag="RHX21_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone DjlA"
                     /protein_id="HDV1988637.1"
                     /translation="MQYWGKIIGVAVALLMGGGFWGVVLGLLIGHMFDKARSRKMAWF
                     ANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFR
                     VGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEE
                     LGISRAQFDQFLRMMQGGAQFGGGYQQQTGGGNWQQAQRGPTLEDACNVLGVKPTDDA
                     TTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK"
     gene            1078..3432
                     /gene="lptD"
                     /locus_tag="RHX21_003494"
     CDS             1078..3432
                     /gene="lptD"
                     /locus_tag="RHX21_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly protein LptD"
                     /protein_id="HDV1988638.1"
                     /translation="MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQ
                     GDTNDLPVTINADHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVR
                     TVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGEN
                     RYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQL
                     PVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEF
                     RYLSQAGAGLMELDYLPSDKVYEDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKV
                     SDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEP
                     QLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTE
                     AKLLATHYQQTNLDWYNSRNTTKLDESVNRVMPQFKVDGKMVFERDMEMLAPGYTQTL
                     EPRAQYLYVPYRDQSDIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRI
                     YDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISERWGLRG
                     GIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGI
                     SQVGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWD
                     NDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL"
     gene            3485..4771
                     /gene="surA"
                     /locus_tag="RHX21_003495"
     CDS             3485..4771
                     /gene="surA"
                     /locus_tag="RHX21_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase SurA"
                     /protein_id="HDV1988639.1"
                     /translation="MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDG
                     LMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIAN
                     IAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESL
                     AQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIA
                     HSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGE
                     SKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGS
                     ANQGGDLGWATADIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAA
                     QKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN"
     gene            4771..5760
                     /gene="pdxA"
                     /locus_tag="RHX21_003496"
     CDS             4771..5760
                     /gene="pdxA"
                     /locus_tag="RHX21_003496"
                     /EC_number="1.1.1.262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase
                     PdxA"
                     /protein_id="HDV1988640.1"
                     /translation="MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLT
                     DRAAMLGLPLTLRTYSPNSPAQPQTAGTLTLLPVALRESVTAGQLAVENGHYVVETLA
                     RACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRV
                     ALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHM
                     GTEEIDTIIPLLDELRAQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQ
                     GFGRGVNITLGLPFIRTSVDHGTALELAGRGEADVGSFITALNLAIKMIVNTQ"
     gene            5757..6578
                     /gene="rsmA"
                     /locus_tag="RHX21_003497"
     CDS             5757..6578
                     /gene="rsmA"
                     /locus_tag="RHX21_003497"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HDV1988641.1"
                     /translation="MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEI
                     GPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAE
                     KMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRL
                     SVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAF
                     NQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPLQES"
     gene            6581..6958
                     /gene="apaG"
                     /locus_tag="RHX21_003498"
     CDS             6581..6958
                     /gene="apaG"
                     /locus_tag="RHX21_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Co2+/Mg2+ efflux protein ApaG"
                     /protein_id="HDV1988642.1"
                     /translation="MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQ
                     LLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMI
                     DENGVPFSIDIPVFRLAVPTLIH"
     gene            6965..7807
                     /gene="apaH"
                     /locus_tag="RHX21_003499"
     CDS             6965..7807
                     /gene="apaH"
                     /locus_tag="RHX21_003499"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     ApaH"
                     /protein_id="HDV1988643.1"
                     /translation="MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPG
                     SLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWL
                     RRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMP
                     NNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVA
                     EEYSIAFGHWASLEGKGTPEGIYALDTGCCWGGSLTCLRWEDKQYFVQPSNRHKDLGE
                     AAAS"
     gene            complement(7885..8364)
                     /gene="folA"
                     /locus_tag="RHX21_003500"
     CDS             complement(7885..8364)
                     /gene="folA"
                     /locus_tag="RHX21_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020456510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 3 dihydrofolate reductase"
                     /protein_id="HDV1988644.1"
                     /translation="MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGR
                     HTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQ
                     FLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR"
     gene            complement(8556..10418)
                     /gene="kefC"
                     /locus_tag="RHX21_003501"
     CDS             complement(8556..10418)
                     /gene="kefC"
                     /locus_tag="RHX21_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     protein KefC"
                     /protein_id="HDV1988645.1"
                     /translation="MDSHTLVQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPW
                     GLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLG
                     LFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMVTQMGRSAFAVLLFQDIAAI
                     PLVAMIPLLATSSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREV
                     FSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLF
                     FIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQ
                     GSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREA
                     DEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDA
                     TRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQ
                     AGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTK
                     ARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS"
     gene            complement(10411..10941)
                     /gene="kefF"
                     /locus_tag="RHX21_003502"
     CDS             complement(10411..10941)
                     /gene="kefF"
                     /locus_tag="RHX21_003502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     oxidoreductase KefF"
                     /protein_id="HDV1988646.1"
                     /translation="MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNI
                     DIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLW
                     AVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQA
                     RHYKQRLLEWQEAHHG"
     gene            complement(11049..12380)
                     /locus_tag="RHX21_003503"
     CDS             complement(11049..12380)
                     /locus_tag="RHX21_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1988647.1"
                     /translation="MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQL
                     TPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMF
                     VSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADL
                     VGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFG
                     EPVAFDEEQPQQTRFRDLFNRRHFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLG
                     VGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGI
                     WLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPI
                     FINNYGISNTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRGQRMG"
     gene            complement(12439..12726)
                     /gene="fixX"
                     /locus_tag="RHX21_003504"
     CDS             complement(12439..12726)
                     /gene="fixX"
                     /locus_tag="RHX21_003504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like protein FixX"
                     /protein_id="HDV1988648.1"
                     /translation="MTSPVNVDVKLGVNKFNVDEEHPHIVVKADADKQALELLVKACP
                     AGLYKKQDDGSVRFDYAGCLECGTCRILGLGSALEQWEYPRGTFGVEFRYG"
     gene            complement(12723..14009)
                     /locus_tag="RHX21_003505"
     CDS             complement(12723..14009)
                     /locus_tag="RHX21_003505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDV1988649.1"
                     /translation="MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKN
                     VTGGRLYAHSLEHIIPGFADSAPVERLITHEKLAFMTEKSAMTMDYCNGDETSPSQRS
                     YSVLRSKFDAWLMEQAEEAGAQLITGIRVDNLVQRDGKVVGVEADGDVIEAKTVILAD
                     GVNSILAEKLGMAKRVKPTDVAVGVKELIELPKSVIEDRFQLQGNQGAACLFAGSPTD
                     GLMGGGFLYTNENTLSLGLVCGLHHLHDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEY
                     SAHVVPEAGINMLPELVGDGVLIAGDAAGMCMNLGFTIRGMDLAIAAGEAAAKTVLSA
                     MKSDDFSKQKLAEYRQHLESGPLRDMRMYQKLPAFLDNPRMFSGYPELAVGVARDLFT
                     IDGSAPELMRKKILRHGKKVGFINLIKDGMKGVTVL"
     gene            complement(14060..15001)
                     /locus_tag="RHX21_003506"
     CDS             complement(14060..15001)
                     /locus_tag="RHX21_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HDV1988650.1"
                     /translation="MNTFSQVWVFSDTPSRLPELMNGAQALANQINTFVLNDADGAQA
                     IQLGANHVWKLNGKPDDRMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYR
                     LKAAVSNDASTVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDAS
                     RTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKENIALAEQLC
                     KAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQT
                     IFAINKDKNAPIFQYADYGIVGDAVKILPALTAALAR"
     gene            complement(15016..15786)
                     /locus_tag="RHX21_003507"
     CDS             complement(15016..15786)
                     /locus_tag="RHX21_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414583.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein FixA"
                     /protein_id="HDV1988651.1"
                     /translation="MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEA
                     ACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTAS
                     ALAAAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLAADTLTVE
                     RELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAEAA
                     WSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI"
BASE COUNT         3912 a         4482 c         4046 g         3576 t
ORIGIN      
        1 ttaaaactta tttaaaccct ttctgctgct ttatcagctc atatgcctgc tgaatttcct
       61 gcgctttctg cttcgccatc tccatcatct caggcggcaa acctttcgcc accagcttat
      121 cgggatggtg ttcactcatc agcttacggt aggcacgttt gatggtggtc gcatcatccg
      181 tcggcttcac gcccagcaca ttacaggcat cttccagcgt tgggccacgc tgcgcttgct
      241 gccagttacc accgccagtt tgctgctgat aaccgccgcc aaactgtgca ccgccctgca
      301 tcatgcgcaa aaactggtca aactgggcgc gggagatccc taattcttca gcaatgacat
      361 acagcaccgc ccgttcattc gggtgcagtg aaccatcagc aaacgccgcc tgaatctgga
      421 tctccagaaa catacgaatt aagtcaaaac gaccaaagca gacactgcga aactggcgca
      481 tcttttcgcg cagcgggtaa ttgtctgatt ttcccacccg gaacgcattt tgcgccgcag
      541 tacgggaagc gccatgaaga ttcattcggt ccatcaactg gctggcgata tgaatatcag
      601 cctccgtgac gcgacctttg gatttggtta aatgccccat cacttcaaaa gtggtggcaa
      661 aaaacagcgc ctgacgctca cgctggttgg cgaaccacgc cattttacgg ctacgggctt
      721 tatcaaacat atggccaatt aacaggccta acactacgcc ccaaaagccg ccgcccatca
      781 gtaaggccac ggccacgcca atgatttttc cccaatactg catatattcc ccaaatcgac
      841 acacggatat cagggctatc tcccacaata taaaggtgct tttaccgttt tccggctgcg
      901 gtcaattgtg ggacatcgcc tataatttgc attatcatac ctgtcattca atgccgtgcc
      961 taacaccact gacgctattc ggacaggatt aacactagcg tagagatgac gagtacgtta
     1021 gtctctgacc gtttgtcacg cgcaacgtta ccgatgatgg aacaataaaa tcaacgtatg
     1081 aaaaaacgta tccccactct cctggccacc atgattgcca ccgcccttta tagtcaacag
     1141 ggactggcag ccgacctcgc ctcacagtgc atgttgggcg tgccaagcta tgaccgtcct
     1201 ctggtacagg gcgataccaa tgacttaccc gtgactatca atgctgacca cgcgaaaggg
     1261 gactacccgg atgacgccgt gtttactggc agcgtggata tcatgcaggg taacagccgt
     1321 ctgcaggccg acgaagtgca gctccatcaa aaagaggcac caggacaacc ggagccggta
     1381 cgtaccgttg atgcgctcgg taatgtccat tacgacgata accaggtgat cctcaaaggg
     1441 ccgaaaggct gggcgaatct gaacaccaaa gataccaacg tctgggaagg tgattaccag
     1501 atggtgggtc gccagggtcg cggtaaagcg gacctgatga aacaacgtgg cgaaaaccgc
     1561 tataccattc tggataacgg tagctttacc tcctgtctgc cgggttctga cacctggagc
     1621 gtggtaggta gcgaaattat tcatgaccgc gaagaacaag ttgcggagat ctggaacgcc
     1681 cgctttaagg tgggtccggt accgatcttt tatagcccct atttgcagtt gccggtgggt
     1741 gacaaacgtc gctctggttt cttgatcccg aacgccaagt acaccaccac caactacttt
     1801 gagttctacc tgccatatta ctggaacatc gcgccaaata tggatgccac catcacgccg
     1861 cattatatgc atcgtcgtgg caacatcatg tgggagaacg aattccgcta cctctcccag
     1921 gcgggcgctg gcttgatgga actggactat ctgccttcag ataaagtcta tgaagatgaa
     1981 cacccgaacg atgacagttc acgtcgttgg ttattctact ggaaccactc cggggtcatg
     2041 gatcaggtgt ggcgtttcaa cgtcgactac accaaggtca gcgatcctag ctacttcaat
     2101 gatttcgata acaagtacgg ttccagtact gacggctacg caacgcaaaa attcagcgtt
     2161 ggctatgcgg tgcaaaactt caatgccacc gtttcaacca agcagttcca ggttttcagc
     2221 gaacagaaca ccagtagcta ctcggcagag ccgcagttag acgttaatta ctaccagaat
     2281 gatgttggtc cgtttgatac gcgtatttac ggccaggcag tgcactttgt taacaccaga
     2341 gacgacatgc ctgaagcaac ccgtgttcac ctggaaccga ccatcaattt gccgctctct
     2401 aataactggg gcagcatcaa taccgaagcg aagttgctgg caacccatta tcagcaaact
     2461 aatcttgact ggtataactc cagaaacacg accaagctgg acgaatccgt taaccgcgta
     2521 atgccgcaat tcaaagttga cggcaaaatg gtctttgaac gcgatatgga aatgctggct
     2581 ccgggttata cccaaacgct ggaaccgcgc gcgcagtatt tgtacgtgcc gtatcgcgat
     2641 cagagcgaca tctataacta cgactcatct ctgctgcaat ctgactactc tggcctgttc
     2701 cgggaccgga cttacggcgg tcttgaccgt attgcctccg ctaaccaggt gacgaccggt
     2761 gtcacatctc gcatatatga tgatgctgcc gttgaacgtt ttaatatttc cgttggtcaa
     2821 atctactatt tcacggagtc tcgcactggc gatgacaaca taacatggga gaatgacgac
     2881 aaaacgggct cactggtgtg ggcaggcgat acttactggc gtatctccga gcgttgggga
     2941 ttgcgtggcg ggattcagta cgatacacgt ctggataacg tagcgaccag taactccagc
     3001 attgaatacc gtcgggatga agaccgtctg gtacagctga attaccgtta cgccagcccg
     3061 gaatatattc aggctacgct gcctaagtac tattccactg ctgagcaata taagaatggt
     3121 atttcgcagg taggtgctgt cgccagctgg ccaattgccg atcgttggtc cattgttggg
     3181 gcctactact acgacaccaa tgcgaacaag caagccgact ctatgttagg tgtgcaatac
     3241 agctcctgct gctatgcaat tcgcgtcggt tacgagcgga agctgaacgg ttgggataac
     3301 gataaacaac atgcggtata tgacaacgca atcggcttta acatcgaact tcgcggcctg
     3361 agctccaact acggtctggg tacgcaagag atgctgcgtt cgaacattct gccgtatcaa
     3421 aacactttgt gatttgttga tttaccacgt aatccgcagt gcggttaatt gaaatggaaa
     3481 aagtatgaag aactggaaaa cgctgcttct cggtatcgcc atgatcgcga ataccagttt
     3541 cgctgccccc caggtagtcg ataaagtcgc agccgtcgtc aataacggcg tcgtgctgga
     3601 aagcgacgtt gatggattaa tgcagtcggt aaaactgaac gctgctcagg caaggcagca
     3661 acttcctgat gacgcgacgc tgcgccacca aatcatggaa cgtttgatca tggatcaaat
     3721 catcctgcag atggggcaga aaatgggagt gaaaatctcc gatgagcagc tggatcaggc
     3781 gattgctaac atcgcgaaac agaacaacat gacgctggat cagatgcgca gccgtctggc
     3841 ttacgatgga ctgaactaca acacctatcg taaccagatc cgcaaagaga tgattatctc
     3901 tgaagtgcgt aacaacgagg tgcgtcgtcg catcaccatc ctgccgcagg aagtcgaatc
     3961 cctggcgcag caggtgggta accaaaacga cgccagcact gagctgaacc tgagccacat
     4021 cctgatcccg ctgccggaaa acccgacctc tgatcaggtg aacgaagcgg aaagccaggc
     4081 gcgcgccatt gtcgatcagg cgcgtaacgg cgctgatttc ggtaagctgg cgattgctca
     4141 ttctgccgac cagcaggcgc tgaacggcgg ccagatgggc tggggccgta ttcaggagtt
     4201 acccgggatc ttcgcccagg cattaagcac cgcgaagaaa ggcgacattg ttggcccgat
     4261 tcgttccggc gttggcttcc atattctgaa agttaacgac ctgcgcggcg aaagcaaaaa
     4321 tatctcggtg accgaagttc atgctcgcca tattctgctg aaaccgtcgc cgatcatgac
     4381 tgacgaacag gcccgtgtga aactggaaca gattgctgct gatatcaaga gtggtaaaac
     4441 gacttttgct gccgcagcga aagagttctc gcaggatcca ggttctgcta accagggcgg
     4501 cgatctcggt tgggcaacag cggacatttt tgatccggct ttccgtgacg ccctgacccg
     4561 cctgaacaaa ggtcaaatga gtgcaccggt tcactcttca ttcggctggc atttaatcga
     4621 actgctggat acccgtaatg tcgataaaac cgacgctgcg cagaaagatc gtgcataccg
     4681 catgctgatg aaccgtaagt tctcggaaga agcagcaagc tggatgcagg aacaacgtgc
     4741 cagcgcctac gttaaaatcc tgagcaacta atggttaaaa cccaacgtgt tgtgatcact
     4801 cccggcgagc ccgccgggat tggcccggac ttagttgtcc agcttgcaca gcgtgagtgg
     4861 ccggtcgaac tggttgtttg tgccgatgcc actctcctta ccgaccgggc agcgatgctc
     4921 ggtttgccgc tcaccctccg cacttattcc cccaactctc ctgcacaacc gcaaactgcg
     4981 ggcacattaa cgctacttcc tgtcgcgcta cgtgaatctg tcactgcggg gcagttagcg
     5041 gttgaaaatg ggcattatgt ggtggaaacg ctggcgcgag cgtgcgatgg ctgtctgaac
     5101 ggtgaatttg ctgcgctgat cacaggcccc gtgcataaag gcgtcattaa cgacgcaggc
     5161 attccgttta ccggtcatac cgagtttttc gaagagcgtt cgcaggcgaa aaaagtggtg
     5221 atgatgctgg cgaccgaaga acttcgcgtg gcgctggcaa cgacgcattt accgctgcgc
     5281 gatatcgcag atgctatcac ccctgcgctt ttgcacgaag tgattgctat tttgcatcac
     5341 gatttgcgga ccaaatttgg tattgccgaa ccgcgcattc tggtctgcgg gctgaatcca
     5401 cacgcgggcg aaggcggtca tatgggtacg gaagagatag acaccattat tccgctgctc
     5461 gacgagttgc gggcgcaggg gatgaaactt aacgggccgc tgcctgccga taccctgttt
     5521 cagccgaaat atctcgataa cgccgacgcc gtgctggcga tgtaccacga tcagggtctt
     5581 cccgtgctaa aataccaggg cttcgggcgc ggtgtgaaca ttacgctggg cctgcccttt
     5641 attcgcacat cagtggacca cggcaccgcg cttgaactgg cgggacgtgg cgaagccgat
     5701 gtcggcagtt ttattacggc gcttaatctc gccatcaaaa tgattgttaa cacccaatga
     5761 ataatcgagt ccaccagggc cacttagccc gtaaacgctt cgggcaaaac tttctcaacg
     5821 atcagttcgt gatcgacagc attgtttctg ccattaaccc gcaaaagggc caggcaatgg
     5881 tcgaaatcgg ccccggtctg gcggcattga ccgagccggt cggcgaacgt ctggaccagc
     5941 tgacggtcat cgaacttgac cgcgatctgg cggcacgtct gcaaacgcat ccattcttag
     6001 gcccgaaact gacgatttat cagcaggatg cgatgacctt taactttggc gaactggccg
     6061 agaaaatggg tcagccgctg cgtgttttcg gcaacctgcc ttataacatc tccacgccgt
     6121 tgatgttcca tctgtttagc tatactgatg ccattgccga catgcacttt atgttgcaaa
     6181 aagaggtggt gaatcgtctg gttgcaggac cgaacagcaa agcgtatggt cgattaagcg
     6241 tcatggcgca atactattgc aacgtgatcc cagtgctgga agtaccgccg tcagccttta
     6301 caccaccacc caaagtggat tccgccgtcg tgcgcctggt tcctcatgca acgatgcctc
     6361 acccggttaa agatgttcgt gtgttgagcc gcatcaccac cgaagccttt aaccagcgtc
     6421 gtaaaaccat tcgtaacagc ctcggcaacc tgtttagcgt cgaggtgtta acgggaatgg
     6481 ggatcgaccc ggcgatgcga gcggaaaata tctctgtcgc gcaatattgc cagatggcga
     6541 actatctggc ggagaacgcg cctttgcagg agagttaacg atgatcaatt cgccccgagt
     6601 gtgtattcag gttcaaagcg tctacattga ggcacaatct tcacctgata atgaacgtta
     6661 cgtttttgct tataccgtaa ccatacgcaa tctggggcga gcgccagtgc agttgttggg
     6721 gcgttactgg ctgatcacca atggcaatgg ccgtgaaacc gaagtccagg gcgaaggagt
     6781 ggttggcgtc cagccactta tcgcgcctgg cgaagagtac cagtacacca gcggtgcaat
     6841 cattgaaacc ccgctgggca ccatgcaggg tcactacgaa atgatcgatg aaaatggcgt
     6901 ccctttcagc atcgacattc ccgtattccg actcgccgtt cccacactca ttcattaaaa
     6961 gaatatggcg acatacctta ttggcgacgt tcatggttgt tacgatgaac tgatcgcatt
     7021 gctgcataaa gtagaattta cccctgggaa agataccctc tggctgacgg gcgatctggt
     7081 cgcgcgcggg ccgggttcgc tggatgttct gcgctatgtg aaatccttag gcgacagcgt
     7141 acgtctggtg ctgggcaatc acgatctgca tctgctggcg gtatttgccg ggatcagccg
     7201 caataaaccg aaagatcgcc tgacaccgct gctggaagcg ccggatgccg acgagctgct
     7261 taactggctg cgtcgccagc ctttgctgca aatcgacgaa gagaaaaagt tggtgatggc
     7321 ccacgcaggg atcacgccgc agtgggatct acagaccgcc aaagagtgcg cgcgcgatgt
     7381 agaagcggtg ctatcgagtg actcctatcc cttctttctc gacgctatgt acggcgatat
     7441 gccaaataac tggtcaccgg aattgcgggg gctgggaaga ctgcgtttta tcaccaacgc
     7501 ctttacccgt atgcgttttt gctttccaaa cggtcaactg gatatgtaca gcaaagaatc
     7561 gccggaagaa gcccctgccc cactgaaacc gtggtttgcg attcctggcc ctgtcgctga
     7621 agaatacagc atcgcctttg gtcactgggc atcgctggaa ggcaaaggta cgccggaagg
     7681 tatttacgcg ctggataccg gctgctgctg gggtgggtca ttaacctgcc tgcgctggga
     7741 agataagcag tattttgtcc agccgtcgaa ccggcataag gatttgggcg aagcggcggc
     7801 gtcttaaaca cagcctgata taggaaggcc ggataagacg cgaccggcgt cgcatccggc
     7861 actagccgta aattctatac aaaattaccg ccgctccaga atctcaaagc aatagctgtg
     7921 agagttctgc gcatcagcat cgtggaattc gctgaatacc gattcccagt catccggctc
     7981 gtaatccggg aaatgggtgt cgccttccac ttctgcgtcg atatgcgtca gatacagttt
     8041 ttgcgctttt ggcaggaact gctcataaac gcgaccgccg ccaatcacca tgatttctgg
     8101 tacgtcacca cacgccgcga tggcttcatc caccgacttc acccacgtta cgcgatcgtc
     8161 cgtacccggt tgactgctga ggataatatt tttgcgtcct ggcaacggac gaccgattga
     8221 ttcccaggta tggcggccca taatcacggg tttatttaag gtgttgcgtt taaaccaggc
     8281 gagatcggca ggcaggttcc acggcatggc gttttccatg ccgataacgc gatctaccgc
     8341 taacgccgca atcagactga tcattgagat ttcccgataa aaaaaattgt cgccactata
     8401 cgtaaagcgt aaaccgtcgt cgactggtgc gaggatgatg ttgaggaaaa ttttatattc
     8461 tgctggcgag tccacgctct ctccctggac tcgccgcatt acaatgaaac aaaaacaaac
     8521 agttagctgt aaagtgtgat ttacgtcact ctttattagg atgagggttt cgtttccggt
     8581 tcatccgcca tgttgccggt atgtttacct tcttcggttc cctgccagcc atgtcgttga
     8641 attaatgaca gatgttcgcg gtcctcggta atgatctcac ttaacatcgc gctggtgcgt
     8701 ttatagaccg ccgcgcgggc tttggtgtcg ttctcaacca ttgccatctc ttccaccatc
     8761 tgaatattaa agcggcggaa cacatcggca cgttctcgcg cttcatacgg ccccagacct
     8821 aaactttcca gtgccagacg cccggttttc agcgcacctt cgaaggtttc acgctccggc
     8881 ttttcaacgc ctgcctgacg caaacgaatg tagtggtcga catcgcgggc gcgggcaata
     8941 atctgcaaat gcgggaaatg ttctttcacc atctctgtca gttgcaggtt ggtttgcgga
     9001 tcgtcgatgg cgttaatcag cacttccgct ttcgccgctc cggcagattc cagtaaatcc
     9061 atccgcgtgg catcgccata aaacactttc ataccaaatt tacgcaaggt ttcgatatgg
     9121 tccggatcgt gatcgagtac caccattttc accccgctgg agagcagtaa acgtccggta
     9181 atctgcccaa aacgaccgaa tccggcgata atcacgcgcg gctgttcttc gtcgatctca
     9241 tcggcttcac gcgcttcctc agtagaagat tgctcaaggc gattgaggat caccagcaga
     9301 atcggcgttg ctgccatcga cagcgccacc gccagggtca gcgatttcgc ccactccggc
     9361 tccagcacat tcgccatctg cgccgcgcca aataccacaa aggcaaactc actgccctgc
     9421 cctaacaaca ccgcaaacca acgacgctgt ttatttggca cttgcaacgg tcgggcaatc
     9481 agccacagca tggcgatttt gatgatgagg aaaccgagca gcaaaatgac aatgcgcaat
     9541 gggttttcaa gcagcgtgcc aaagtctatc gacatgccaa caccgatgaa aaacagcccc
     9601 aacagcaaac ctttaaatgg ttcgatatcg ctctccagcg catgacggta ttccgaactt
     9661 gccagcagta cgcccgccag aaacgcgccc atcgccatcg acaagccgac ctcttccagc
     9721 agcaaaccaa agccaaacac gaggaataac gccacggcac taaacacttc ccgcaagcca
     9781 gagcgggcta caaaacgcag cgccggacgc gtgacatagc gccccagcaa taccaccagc
     9841 accagcgcac ccgccacttt taacgccgag agagcaaatg cgcccatcgt cgtcgaggca
     9901 ctgctcgttg ccagtagcgg aatcatcgcc accagcggga tcgccgcgat atcctggaac
     9961 agcagcaccg caaaggcact gcgacccatt tgcgtcacca tcagattgcg ttcattcatc
    10021 gcctgcatgg caatcgccgt agaggagagc gccagcgtca tgccgatcaa ttccgcgacc
    10081 tgccagcgca gcccaagtaa catgcagaac agccccagca ggccgccgca aatcaccatc
    10141 tgcaatgcgc cgccgccgaa cactgccgca cgcagcttcc atagcctttg tggatcgagt
    10201 tcgaggccaa taataaacag catcagcacc acgccaatct cggcaaagtg caggatagat
    10261 tcggcatcgg tcaccagtcg cagcccccac gggccaataa tgcagccggc aatcaggtag
    10321 ccaagtaccg atcccagacc aagacgtacc gcaatgggta caatcagcgc cgccgatccg
    10381 aggtagatca gcgcctgaac cagcgtatgg ctatccatga tgggcctcct gccattccag
    10441 cagacgttgc ttatagtgac gcgcctgccc ttcgagggtt tcgtcgtcac aaataaaggt
    10501 gcagtgcatg gcaaacggtg gcagccagtt cagcccgcag tagattgccg tcgcctgtag
    10561 cggctgcgac agcacatcaa agcccggatg cgcaccaatt tcaaaatggc tttccccgcc
    10621 gccggtcgtc accgcccaca gcaaatgttt gccatgcagc gccgtgccgc cgtgaccgta
    10681 agcccagccg tgcgagaaaa ctttatcgat ccaaagtttg aggagcggtg gaatgctgta
    10741 ccactgcatc gggtgctgcc agacgatcag atcggcgcga gacagcgcct cctgctcggc
    10801 ggcaatatcg atattgaagt caggatagag ttgataaaga gagcgaattt cgacgccttc
    10861 cagcgtcctt gcctgttcaa gcatccgttt attcgcatgg gaatgatgcg gatacggatg
    10921 cgcataaatt ataagaatca taggtagccc gcgtgattac gcctttgttt tcccacaaag
    10981 tgtagtcata tattcacgcg gcttatagtc aataatattg attcagaaaa gagagaaatc
    11041 tgaacaattt accccattct ctgcccgcgg atcgtcatat tgctggtttg cgccagtgac
    11101 atccctcgag tctccggggc aaacgctacg gaaatcaaca agccaaacag cgagataccc
    11161 gcccccatta gcatcgtgtt actgataccg taattattga taaagatcgg cagtgcccag
    11221 gtcgaaacaa tggtgccaat acggcttaag gacataatca cgcccacggc agaggcgcgg
    11281 atatctgtcg ggaagagttc attaggatag agccactgca aattacccgg cccgccagag
    11341 aaaaaggcat acaccgcaaa ggccatcact accagccaga tccccatatc cgggatcagc
    11401 cccaaaaccg ccagcgccag cgtcatcatg gcaaagctgc caatcaacaa tggacgccgt
    11461 ccggcagtgt ttagccacag catcggcgga atacagccga gcataaagaa caggctaatc
    11521 accacgttcc ccagtgccgc gtttttgcca acccccaatc ccaacaaacc aacgatttgc
    11581 gggccaaagg tgtaaatggc gaacattggg atcacctggc aggtccagat ggcggcaaca
    11641 aacagaacaa aaggaaaatg gcggcgatta aacagatcgc gaaaacgggt ttgctgcggc
    11701 tgctcttcat cgaaagccac cggttcgcca aacagtttta tcatcatctc ttcgcactct
    11761 tttactcgcc ctttgcgtaa taaccagcgg ggagattcag gcagttcgaa tcgaccaatc
    11821 aaaatcaaca aacaggggat cgccgcgcta cccagcatcc agcgccagcc gccttccaca
    11881 tcataaagcc agtagccgac cagatcggcg caggtcgcgc cgacatacca catggcggcg
    11941 ataaagctga tggaaaacgc ccgctgacgg gtactggaga actcggtgat cattgaggtg
    12001 gcgatgggat aatctgcacc gatgacaatg ccgataagta cccgcatcac caacagttcg
    12061 acaggggatg agacaaacat cgtcgccacc gatatcacgc cgatggcgat gatatcaatg
    12121 aggaacattt tgcgccgtcc gactttatcg gaaatatagc caaacagcga tgtgccaacg
    12181 aacagcccgg cgagcgttcc cgcgcccaac aagccaatcc agtcagcgtc cagttttagc
    12241 gccggagtca gttgctccag cgccacgcca atcattacca gtacataacc atccagaaac
    12301 ggaccaccgc ttccccacag caaaatgcgg cggtgaattg aggagaattt gagatcgtca
    12361 aagtttctgg acggttgcat gggttattcc tgtttttttg caatgagagt cagtacggcg
    12421 ttacgtatca aaccaacatc agccgtaacg gaactccaca ccaaaggtgc cgcgcgggta
    12481 ttcccactgt tccagcgccg accccagccc cagaatgcga caggtgccgc actccagaca
    12541 tccggcgtaa tcgaagcgca cactgccgtc atcctgcttc ttgtacagac ctgcggggca
    12601 cgctttcacc agcagctcca gggcctgttt atcggcatcg gccttcacaa caatgtgcgg
    12661 atgctcttca tcgacattga atttattgac gcccagtttg acgtccacat tgacgggaga
    12721 agtcataaaa cggtcactcc tttcatgcca tccttgatca gattgatgaa gcccactttc
    12781 ttgccgtggc ggaggatttt cttgcgcatc agttccggcg cactgccgtc aatggtgaac
    12841 aggtcacgcg ccacgcccac cgccagttcc gggtagccgc taaacatgcg tgggttatca
    12901 aggaaggccg gtagtttctg gtacatacgc atatcgcgca gcgggccact ctcaagatgc
    12961 tgacgatatt ccgccagttt ttgcttactg aaatcgtcgc ttttcatcgc tgaaagcacg
    13021 gtttttgctg cggcttcccc ggcggcaatc gccagatcca taccgcgaat ggtaaaaccg
    13081 aggttcatac acattccggc ggcatcaccg gcaatcaata cgccgtcacc aaccaactcc
    13141 ggcagcatgt tgatgcctgc ttccggcact acgtgagcgg aatattccac cagcttgcca
    13201 cccgcgatca gcggtgcaac ggccggatgt tgtttgaaat cttccagcat ttgcggcacc
    13261 gatttttttg cgtcatgcag atgatgcaga ccacaaacca gccccagcga cagggtattt
    13321 tcattggtat aaaggaagcc gccgcccatc aggccatcgg tgggtgatcc cgcaaacaga
    13381 caagccgcgc cctgattacc ctgcaactga aaacggtctt cgattaccga cttcggtaac
    13441 tcgatcagtt ccttcacgcc aaccgccaca tccgtcggtt taacgcgttt tgccatcccc
    13501 agcttttcgg caaggatgga gttcactcca tcagcaagga tcaccgtttt cgcttcaatc
    13561 acatcgccat cggcttctac accgacgact ttgccatcgc gctgtacgag gttatcgacg
    13621 cggatcccgg taattaactg cgcgcccgct tcttcggcct gctccatcag ccaggcatca
    13681 aatttactgc gcaaaacgga gtaagaacgc tgggatggcg aggtttcgtc accattgcag
    13741 tagtccatag tcatcgctga cttttccgtc ataaacgcga gtttttcatg ggtgatcagg
    13801 cgttctacgg gggcggagtc ggcgaaacca ggaataatgt gttccaggct gtgggcatag
    13861 agacgcccgc cggtgacgtt cttggcacct gcggaattgc cacgctcgat aactaacact
    13921 tgcgcccctt cgcgggcgag caccagtgcg gcaaccgaac cggcaagccc agcaccgacg
    13981 atgatggcgt caaagatatc ttcggacata agagctccct gtcagcggca gggccaaaat
    14041 gcagccctgc cagagtggat caacgcgcta aagctgcggt cagcgccgga aggatcttca
    14101 cggcgtcacc aacaatgccg taatccgcgt actggaagat cggcgcattt ttatctttat
    14161 tgatggcgaa aatggtttgc gatgcattag caccaaccat gtgctggatc tgcccggaga
    14221 tccccaccgc caggtacagt tcaggtttca gcatcaggtt ggagataccg acatagcgtt
    14281 cgtgctccat ccatttttcg ttttccgcca ccggacgaga acaggccaac tccgcaccta
    14341 tcgccttgca aagctgttct gccagcgcaa tgttctcttt gctgccaata ccgcgaccga
    14401 cgctgaccac cagacgggct ttgtcgagat cgacgctgtt gctctggcgc gcctgggttg
    14461 ccgtgcgggt aatcgccaca gccggagcct gccactccac ggtgtgcgtt tcgccagtgc
    14521 gtgacgcgtc tggctgagcc gcatcgaacg tgccgctgct gatggtcagt accgcatacg
    14581 gcgtggcaat gcgttcttcg ccaatcgcca gaccaccgta aaccatgtgt ttcactgtcg
    14641 ctttaccgtc ctgtacgctg acggtgctgg catcgttaga caccgccgct ttaaggcgat
    14701 aacccagttt tgccgccagt aatttgccgc gacgggtgtt tggcagcagc accaggccgt
    14761 ctgcgccgtg ctggcgaata gtgtcagcca tgacaccggc gtaatcttcg atcatccgat
    14821 cgtccggttt gccgtttaat ttccagacat gattagcgcc gagctggatt gcctgtgcgc
    14881 cgtcggcatc attgaggaca aaggtgttga tttgattagc taaagcctgc gcaccgttca
    14941 tcagttccgg cagacgagaa ggggtatcgc tgaataccca gacttgagaa aacgtgttca
    15001 tagcatcccc tgtaattaaa tgactttgcg aagattttca gcaaatgcgg cgatctgttc
    15061 ttcgccgtcg ccttcaatca cgatgcgctg acgttcgcgc tgtttcggcg cggcaacctg
    15121 ttgttctgac caggctgcct ctgcgttaaa accaatatcc gccgccgacc atacctggac
    15181 gggctttttc gccgcgccga gaatggcttt catcgaagga atttgtgggg aattgatatc
    15241 agtggaaaca gcaacaaccg caggcagcgg aatgcttaag gtttcggttt catcttccag
    15301 ttcgcgctca acggtgaggg tatctgcagc cagggagata attttgctga cgccgttaac
    15361 tgccggaata ttgaggattt cgcccaccag cagaccaacc tgctgggcat aaaggtcgga
    15421 agaaccatcg ccacagagga tcaaatcaaa gcctgctttc tgggcggctg cagccagtgc
    15481 gctcgccgtt tgttgcggca gtgcctgctc gaactggtca tcaatcacca caatcagttc
    15541 atccgggccg cgcgatagca catctttacg ccctttggcg ttggtcaggg ctttaccgcc
    15601 cacacttaag gccgtcacct gcgcctctgc tgcctgttgc tttagctggc aagccgcttc
    15661 aatagcgttc agatcgtatt ggcttatttt ggcatcggct ttgctgaagt ctaatgaacc
    15721 atcagcatta ttgaccgcaa tatcctgttc atcaggcacg cacttatagc aagtaataat
    15781 cttcattgca tctccagaaa tcatgaagga aacgtcgttc atatcggtgg tgttaattac
    15841 agatatcacg ccctttaatt tggaaataaa actttaatca ccaatattga aaatgtcaca
    15901 cgcagataaa tccaactttc aatattgtta agttcctcac caatattgaa aacatggcgt
    15961 agcaaaaaga aattttcaat attgctttat ggatcaccaa tattgaaagt cagatg
//
LOCUS       DAPGUL010000103        15535 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.105, whole genome shotgun sequence.
ACCESSION   DAPGUL010000103 DAPGUL010000000
VERSION     DAPGUL010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15535
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.105"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..427)
                     /locus_tag="RHX21_003508"
     CDS             complement(<1..427)
                     /locus_tag="RHX21_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000578510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988652.1"
                     /translation="MIFYLIDKEVKDREMSFNTTHEKSEIYRLILRESELITAWVKSG
                     DTPSAVYGKLRDKNPDIIFSINGFLYNLRNFNYALYETATKNKSKTRLIILNHYDDIA
                     SAIRAGHTLKGVYKLVCPHITYNCFITQLRKTYPDLHSQG"
     gene            complement(1057..1557)
                     /locus_tag="RHX21_003509"
     CDS             complement(1057..1557)
                     /locus_tag="RHX21_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDV1988653.1"
                     /translation="MNNTDSLEKIIKHQQNNDPKYPCQEHLLIQLCIRVNKKIQDNIS
                     SLLSGYGINYSTYMVLTILSTADNHCLSPSKISRELQFTRTNITRITDFLEKAGYIER
                     TDSREDRRAKKISLTSDGLSFIQNVNIAQSLHLKEIWSPLTHAECELFEDINKKLLTH
                     IADVCP"
     gene            complement(1810..2019)
                     /locus_tag="RHX21_003510"
                     /pseudo
     CDS             complement(1810..2019)
                     /locus_tag="RHX21_003510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611483.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2187..2703
                     /locus_tag="RHX21_003511"
                     /pseudo
     CDS             2187..2703
                     /locus_tag="RHX21_003511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001751479.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2594..2941
                     /gene="tnpB"
                     /locus_tag="RHX21_003512"
     CDS             2594..2941
                     /gene="tnpB"
                     /locus_tag="RHX21_003512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HDV1988654.1"
                     /translation="MITLPAGSRIWLVAGITDMRNGFNGLAAKVQNTLKDDPISGHLF
                     IFRGRRGRLVKLLWADSGGLCIYMKRLERGTFIWPVAREGKVYLTPAQLAMLLEGIVW
                     MQPGRSKSNSLRI"
     gene            3051..4570
                     /locus_tag="RHX21_003513"
                     /pseudo
     CDS             3051..4570
                     /locus_tag="RHX21_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005050628.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            complement(4580..5787)
                     /locus_tag="RHX21_003514"
                     /pseudo
     CDS             complement(4580..5787)
                     /locus_tag="RHX21_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015869530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            complement(5911..6747)
                     /locus_tag="RHX21_003515"
                     /pseudo
     CDS             complement(5911..6747)
                     /locus_tag="RHX21_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904571.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            6740..7390
                     /locus_tag="RHX21_003516"
                     /pseudo
     CDS             6740..7390
                     /locus_tag="RHX21_003516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477168.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(7568..7849)
                     /locus_tag="RHX21_003517"
     CDS             complement(7568..7849)
                     /locus_tag="RHX21_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016230754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988655.1"
                     /translation="MSESVKLSFYRVHECGYYLWGNNTPVFGSLQELLTDLHFWSTDK
                     SIENTKLYEPQADSDYLGTYLFNINRSGDYWLVTIWNEVPSTKRELLLL"
     gene            complement(8035..13545)
                     /locus_tag="RHX21_003518"
     CDS             complement(8035..13545)
                     /locus_tag="RHX21_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDV1988656.1"
                     /translation="MINKNKVTERSGIHDTVKSLSENLRKYIEAQYHIRDEGLIAERR
                     ALLQQNETIAQAPYIEATPIYEPGAPYSELPIPEAASNVLTQLSELGIGLYQRPYKHQ
                     SQALESFLGENASDLVIATGTGSGKTESFLMPIIGKLAIESSERPKSASLPGCRAILL
                     YPMNALVNDQLARIRRLFGDSEASKILRSGRCAPVRFGAYTGRTPYPGRRSSRRDELF
                     IKPLFDEFYNKLANNAPVRAELNRIGRWPSKDLDAFYGQSASQAKTYVSGKKTGKQFV
                     LNNWGERLITQPEDRELMTRHEIQNRCPELLITNYSMLEYMLMRPIERNIFEQTKEWL
                     KADEMNELILVLDEAHMYRGAGGAEVALLIRRLCARLDIPRERMRCILTSASLGSIED
                     GERFAQDLTGLSPTSSRKFRIIEGTRESRPESQIVTSKEANALAEFDLNSFQCVAEDL
                     ESAYAAIESLAERMGWQKPMIKDHSTLRNWLFDNLTGFGPIETLIEIVSGKAVKLNIL
                     SENLFPDSPQQIAERATDALLALGCYAQRASDGRVLIPTRMHLFYRGLPGLYACIDPD
                     CNQRLGNHSGPTILGRLYTKPLDQCKCASKGRVYELFTHRDCGAAFIRGYVSSEMDFV
                     WHQPNGPLSEDEDIDLVPIDILVEETPHVHSDYQDRWLHIATGRLSKQCQDEDSGYRK
                     VFIPDRVKSGSEITFDECPVCMRKTRSAQNEPSKIMDHVTKGEAPFTTLVRTQISHQP
                     ASRPIDGKHPNGGKKVLIFSDGRQKAARLARDIPRDIELDLFRQSIALACSKLKDINR
                     EPKPTSVLYLAFLSVLSEHDLLIFDGEDSRKVVMARDEFYRDYNSDLAQAFDDSFSPQ
                     ESPSRYKIALLKLLCSNYYSLSGTTVGFVEPSQLKSKKMWEDVQSKKLNIESKDVHAL
                     AVAWIDTLLTEFAFDESIDSTLRIKAAGFYKPTWGSQGRFGKALRKTLIQYPAMGELY
                     VEVLEEIFRTHLTLGKDGVYFLAPNALRLKIDLLHVWKQCNDCTALMPFALEHSTCLA
                     CGSNSVKTVEPSESSYINARKGFWRSPVEEVLVSNSRLLNLSVEEHTAQLSHRDRASV
                     HATTELYELRFQDVLINDNDKPIDVLSCTTTMEVGVDIGSLVAVALRNVPPQRENYQQ
                     RAGRAGRRGASVSTVVTYSQNGPHDSYYFLNPERIVAGSPRTPEVKVNNPKIARRHVH
                     SFLVQTFFHELMEQGIYNPAEKTAILEKALGTTRDFFHGAKDTGLNLDSFNNWVKNRI
                     LSTNGDLRTSVAAWLPPVLETGGLSASDWFAKVAEEFLNTLHGLAEIVPQTAVLVDEE
                     NEDDEQTSGGMKFAQEELLEFLFYHGLLPSYAFPTSLCSFLVEKIVKNIRGSFEVRTV
                     QQPQQSISQALSEYAPGRLIVIDRKTYRSGGVFSNALKGELNRARKLFNNPKKFIHCD
                     KCSFVRDPHNNQNSENTCPICGGILKVEIMIQPEVFGPENAKELNEDDREQEITYVTA
                     AQYPQPVDPEDFKFNNGGAHIVFTHAIDQKLVTVNRGKNEGESSGFSVCCECGAASVY
                     DSYSPAKGAHERPYKYIATKETPRLCSGEYKRVFLGHDFRTDLLLLRITVGSPLVTDT
                     SNAIVLRMYEDALYTIAEALRLAASRHKQLDLDPAEFGSGFRILPTIEEDTQALDLFL
                     YDTLSGGAGYAEVAAANLDDILTATLALLESCECDTSCTDCLNHFHNQHIQSRLDRKL
                     GASLLRYALYGMVPRCASPDIQVEKLSQLRASLELDGFQCIIKGTQEAPMIVSLNDRS
                     IAVGSYPGLIDRPDFQHDVYKSKHTNAHIAFNEYLLRSNLPQSHQNIRKMLR"
     gene            complement(13542..14585)
                     /locus_tag="RHX21_003519"
     CDS             complement(13542..14585)
                     /locus_tag="RHX21_003519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001519246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988657.1"
                     /translation="MEWRAVSRDKALDMLSTALNCRFDDEGLRISAVSECLRSVLYQY
                     SISETEEARQTVTSLRLTSAVRRKLVPLWPDIADIDNAIHPGIMSILNSLAELGDMIK
                     LEGGNWLTAPPHAVRIDNKMAVFFGGEPSCTFSTGVVAKSAGRVRLVEEKVCTGSVEI
                     WDANEWIGAPAEGNEEWSSRLLSGTISGFIDAPGNMSETTAYVRGKWLHLSELSFNKK
                     QIYLCRMSVDNHFSYYLGEIEAGRLCRMNSLESSDDVRRLRFFLDTKDNCPLKVRIKI
                     SNGLARLRLTRRLPRRETKVLLLGWRESGFENEHSGITHHVFPEEILPIVRSAFEGLG
                     IIWINEFTRRNEI"
     gene            complement(14597..>15535)
                     /locus_tag="RHX21_003520"
     CDS             complement(14597..>15535)
                     /locus_tag="RHX21_003520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001519245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988658.1"
                     /translation="ERIDTLEINTSQASEVSVTNRFTKFHEIAHYENYEYLSSSEDIS
                     NRISLNLQAVGLTKNSAEKLARLTLATFVSGQIIQFSGSLADIIADAIAIAIGAPRYH
                     IWRVPVGIISDMDAFDFIETIAESSRCLLLKGANLSAFEIYGAAIRDIVVQRQIHPTN
                     YDHLALIATWKQGPATFPDGGMLAELGPVIDTDTLKMRGLSATLPQLKPGCLAKDKWT
                     NIDGLHLDSVDDYVDELRALLDEAGFDGGTLWKRMIHIFYTSLIRIPNGNYIYDLYSV
                     LSFYTLTWAKIKGGPVQKIEDIANRELKNYSAKISS"
BASE COUNT         4147 a         3610 c         3440 g         4338 t
ORIGIN      
        1 taccctgaga atgcaggtca ggataggttt tcctgagttg tgtaataaaa cagttatatg
       61 ttatatgtgg gcatacgagt ttgtaaacac ctttaagcgt atgaccagca cggatagctg
      121 atgcaatatc atcataatgg ttgagtatta ttaaccttgt tttgcttttg ttctttgtgg
      181 ctgtttcata tagtgcatag ttaaagttac gtaggttata taaaaagcca tttatcgaaa
      241 agattatatc cgggttttta tcacgtagtt ttccgtaaac tgctgacggc gtgtctccag
      301 attttaccca tgctgtaatg agttcacttt ctctaaggat cagacgatag atttcagatt
      361 tctcgtgtgt ggtattaaaa ctcatctctc ggtccttaac ttctttgtca atgagataaa
      421 aaatcatatt tctataattt agtcaacact ctgtgctaca tgcgatatgg atataccagc
      481 aatatgcaat gcgtgagaaa atgatgtttt tattgcatca tctatgatga gtgaaaacaa
      541 ctaaagttga aagctacaca aaactggccc catagttatc gggactgaat accataaacc
      601 attcatagtc aagcgtgtat tcaaccatat cagttaaacc ggtttgactg gcctgaaagt
      661 atctccatat ccgttgtgat aattttgttc tctttagtgt agaactttaa agtaatgtgt
      721 tgagaagctc aactatatta ataaaaataa gatagattga acaattataa acaatgttgc
      781 aactattttt attgcgcgtt accccatatg agataagctc aatcattacg ttatcttgta
      841 tcagtaagtt ctacggtgaa tcatgctgat atttgcgggt taggcaccgc atcattcaca
      901 agaaccgtcg tatgagtttg tcattttgct gcattgtgac ctaaaccagt agttttcttg
      961 tatcgctgtt tccgcctgta gttatgtcgc tcttatgcct gcttattata tgattcattg
     1021 cttgaagctc ttcagtttcc tcaaactctt catgctttag ggacacacat cagcaatatg
     1081 cgtcagtaat tttttattaa tgtcttcaaa cagttcacac tctgcatggg tcagcgggct
     1141 ccagatttct ttcaggtgca gactttgtgc aatattgacg ttctgaataa aggacagacc
     1201 atctgatgtc agactgattt ttttagcacg gcgatcctct ctgctatcag ttctttctat
     1261 ataccctgct ttttctaaaa aatctgtaat gcgggtaatg tttgttctgg taaactggag
     1321 ttctctgctt atctttgagg gcgaaagaca atgattatct gctgtggata atatggtaag
     1381 aaccatatat gttgaataat ttattccata tccactgagt aaactcgata tattatcctg
     1441 tatttttttg tttacgcgga tacagagttg tatcaacaga tgctcctggc aggggtattt
     1501 tggatcgttg ttttgttgat gtttgattat tttttctaat gagtctgtgt tgttcatata
     1561 atcatttcca tttgctgaaa tactttgcct ttatacaaaa gtgcatcaga catgcggtaa
     1621 gcatctactt ttcacaacaa gttatgtctg ccagatatct gtatgaatga gacaaccagg
     1681 cagaaaggaa ggataacttc attcgcataa aaaaacataa atgtttgtag tggtcaacaa
     1741 aaaatgatca cgattttaaa tttttttcca gtatctattt tccaattcgt ttggtagtaa
     1801 cctgccattt tattcgtgag gcctgagtgc actataatac ccaacgatat agtccgttat
     1861 gacttgaact gcatcgctga agcttacgta ccccaccact ggtaaccatt cgttctttag
     1921 actcctgaag atgcgttcca ttgggctgtt atcccagcag tttccctatc ggctgatact
     1981 ttgctttatc ctgtaacacc agagaagttg ttgatatttc agttcagtat actgacctct
     2041 tgcctggctt gatcaactgg taaagtactt caccgttgag cttcccgtgg ttgattttac
     2101 gtaagcgacc cgtcagagac gtcttcaggc agtcgagtga aaacgctaac ttagacgccc
     2161 atctgaaaca gacggacatc taagttatgg aatctgaaac ccgggcctgg cggaccgaac
     2221 cccgccgcgt ttattccagc gaattcaaac tcaggctggt cgaactggct acccgaccgg
     2281 acgccaatgt tgcggatatt gcccgtacgc acggggtcaa cgataacgtc ctttttaaat
     2341 ggatccgtct gtggcgtaaa gaaggccggg tattccgccg gctgccagct cccgttccat
     2401 ctgtatcccc tcctgcggca tttccggtcg aaattgtacc tgactccacc acccggcagt
     2461 ctccggctct gtctggtcag ggaacggggt caacctgctc gctgacgctt cgccacggca
     2521 ccctcacact cgacaatcct gacccggaga tacagctccg gatcgtccgc gaactcgccg
     2581 gcaggagcac agtatgatta cgcttccggc tggcagccgt atctggctcg tggccggcat
     2641 caccgacatg agaaacggct tcaacggtct ggccgcaaag gtccagaaca ccctgaagga
     2701 tgacccgatc tccggccatc tcttcatctt ccggggacgc aggggcaggc tggtaaaact
     2761 cctgtgggca gacagcggag ggctctgcat ctatatgaaa agacttgaac ggggaacgtt
     2821 catctggccg gtcgcccggg agggaaaggt gtatctgacc ccggcacagc ttgccatgct
     2881 gctggagggt atagtctgga tgcaaccggg aaggtcgaaa agtaatagtc tgcggatctg
     2941 aatcccttta cctgggcagg atgaaaaata tcccgcttcc tgataatatc gaccagttga
     3001 aagccctgtt gcgtcagcag caggttgctg tgtaacagct aaatgttacc atgaaaaagc
     3061 agcaggcccg gctgcgccag tacgccggac aggttgccga ctacgaacag gaaatcgaac
     3121 ggctgaaggc acagcttgat aagttgataa gctgcggcgg atgctgttcg ggcagagttc
     3181 agagaaaagc cgcaataaac tggaaaataa aatccgccag gcagagaagc ggctggctga
     3241 gctggaaaac cgtcttgcag cggcaaaacg ctgtctgcag gacgatgagc ccactgtcag
     3301 tacggttgag caggcagagc ccccggtggc ggtcgcccca caggaccggc ctgcacgccg
     3361 ctcccgtcgt cagaaactgc cggcagacct gccacgtgaa acccggcgca tcgccccgac
     3421 agtgactgtc tgcccgaaat gcggcggcga cctgaaggtg atgagtgaaa ccgtctcaga
     3481 gcaactggag ataatccgca gcgcctttaa ggtcatcgaa acggtgcgcc cgaagctggc
     3541 ctgcagccgc tgcgatgtga tagtccaggc cccactcctc ccgaaacctc tgacccgcag
     3601 tgtggccggt gcgggcccgc tggcccgcat cctggtgagt aaatactgtg accatacccc
     3661 gctgcatcgt cagtccgtca tcttcagccg ccagggtgtg gaactgagcc gaaacacgct
     3721 ggtccggtgg gtggcgatga ccgcagaacg actcagtccc ctgcacgatg cgctgaaccg
     3781 ctacgtgatg gagagcagca aacagcacac ggacgatacc ccggtgaaag tgctggagcc
     3841 ggggagcggt aaaactcgga cgggccggct gtgggtgtat gtgcgcgatg accggaacag
     3901 cggttcagcg gctccgccag cggcgtggtt cgcttacagt acagatcgtc ggggctgtca
     3961 cccgcagggg catctggcgg agtggaaagg tatcctgcag gcagatgcgt ttgccggtta
     4021 cgatgcgctt tatgagtcag ggctgatcag ggaagccgcc tgcatggcgc atgcaaggag
     4081 aaagatccat gatgagcatg ttcgccggcc gacagcgatg acaacggagg cgctgaagcg
     4141 tatagccggg ctgtatgcgg tggaagcgac aatccggggt caaccggcag agaaacggct
     4201 ggcagaacgg caggagaaaa gcgtcccgca gatgaaggcg ttgttcgcgt ggctgacaga
     4261 acagatggag acgttgtcgg tgcatgcaga gctggggaaa gcgttcagct atatgctgaa
     4321 ccaccgtgaa gcgcagtcgc tctgttgtga ggacgggcgt gtggaactgg acaataatat
     4381 cgcagaaaac acactgcgtt gtgtcgccct atggcgacgc aactgtctat tcttcggctc
     4441 agacacggga ggtcagagcg cagcgatcct gtacagcctg ctggcgacat gccggctgaa
     4501 tggagtggat ccggaaagct ggttgcgtga ggtaatcagc tgtatcgacc cagtttacca
     4561 ttctgtgtaa atgcctttct cagaagtgac cgtcaaggcg gtcaccgaat ttgataataa
     4621 agcgactcat ggctatccgc cagtcctgaa gtggcatcgt ccatttctgt gaggctgact
     4681 ggatagccag ccacaccact tttttcaccg attcatctgt ctggaacact ttccgtttct
     4741 ttatcgcatg tctgatgacg ctattcagcg attcgattgc gttagtggtg tagataacct
     4801 tgcggatcgc ctccgggtac acgaagaagg tggcaacatt cggccagttt gcccgccaac
     4861 tgcgacttat ctgcgggtac agtgcatcac attccttccc gaacgcatcc agcgcctgaa
     4921 acgcgccttc ttccgtggct gcgcggtaaa cctgtttcag gtcacgggtt accgctttat
     4981 agtctttcca cgccacgaac cgcaggctgt tgcgtaccat gtgtactatg cacaactgga
     5041 tctgcgtctc cgggtagacg gcattaatcg cttccgggaa gcctttcagg ccgtccacgc
     5101 aggcgataag gatatcgttc aggccgcgat ttttcagttc cgtcagtaca ttcagccaga
     5161 actttgcacc ttcattttcg gccagccaca tacctggcag ctctttctga ccatcaaggt
     5221 taatacccag agccaggaac accgctttgt tgataacccg gctgtcctgc cgtactttca
     5281 ggacaataca gtcaagataa ataatgggat aaatcgcatc cagaggacgg ttttgccatt
     5341 caaccacctg gtcgattacg gcatcggtga ctttcgatat cagcgccgga gagacgtctg
     5401 catcgtacat ttctttgaag actgaggtaa tttcgcgggt agtcatccct ctggcataca
     5461 gcccaagatc tggttgtcca tgccggtaat gcgggtctga tttttcttca ccagttgtgg
     5521 ttcgaaggaa ccatcacgat cacgtggagt acgtaattcc atcggcccgt cggtagtggt
     5581 gacggttttc gtggaatagc cattacggga gttggttccc gatttgggct gatttttttc
     5641 atgtcccaga tggtgagtca gttcagcgtt gagagcagcc tcaacactga ttttcttgag
     5701 caggcgatcg aactgactga gatcttcagg ggttttgaga tttttggcca gttcgttagc
     5761 cagagcctgc aattgtttgt cgtccataat ttaaccttca tttgatgttg aattgaacat
     5821 atcaaaatca ggcaattaca caaatctatg tacaggctca aagttatcgc cttatgtaac
     5881 tgctcttgaa agaatcaatg aacaaattga gagccagttt ttccggccta cggccactcc
     5941 ccgtaaggtg ttctctgcaa tgttgttgtc gatttccacc cagccattac tgcagtagac
     6001 gttcagggcc tcccactgtt tcagcaggta tgcgaacgct tttgccgtat ccgagtgacg
     6061 cgacagtgtt ttcatctgag tctgtatcca gtcatacagt gactgcatca gtggcgcagc
     6121 tctggctttt cttgccgcca gatgctgttc tgctgaacat ccccggactt ctgcctcgat
     6181 gacatacagt tcaccgatac gctgcagggc ttccgtggtg atgtcggttg gcactcttgc
     6241 atgcacatcg tggatttttc tccgggcatg agccatacac gcggcttccg ttattctgcc
     6301 ggattcgtat aacacccggt aaccaccgta agcatcggcc tgaaacacac cgctgtagcc
     6361 ggccagatga ttttgtggat ggataccttt ccggtccggt gagtacgcga accagaccgc
     6421 tgggggcatc tgtgaaccgg cattacggtc atcacggacg taggcccaca gccgggcagt
     6481 ccttgtttta ccactgcccg gctcctgtac cggaacgggg atatcatcgg catggacttt
     6541 accgggcacc agcacatact ggcgcaggac gtcatacaac ggctccagca gttcagcaac
     6601 agcgcctgtc cagcgcccca gtgtggcacg gctcagctcc actccctgac gacgatatat
     6661 ttctgactgg cggtataacg gcagatggtc tgcatatttt ccagcgacaa catgggccag
     6721 aagccccgct ccggcataac tgcgtgctca gggttaccac tttaacgtaa aaaccgtgtc
     6781 ggcaagcctg caccgtcagg ggctgagggc aaaggcctcc cggaagttca gtccggtcag
     6841 ttaccgcgca catggcctgc ctgtgtcaga aaatctgttg gagcaggatt tttacgccag
     6901 tggtccgaac cagaagtggg cgggagcatc acgtacttac gtacgtgatg aaggctggct
     6961 gtatctggca gtggtcattg acctgtggtc acgtgctgtt attggctggt ccatgtcgcc
     7021 acgcatgacg gcgcaactgg cctgcgatgc cctgcagatg gcgctgtggt ggcgtaagag
     7081 acccagaaac gttatcgttc actcggaccg cggaagccag tactgttcag cagattatca
     7141 ggcgctgctg aagcggcata atctgcgtgg cagtatgagc gcaaagggct gctgctacga
     7201 taatgcctgc gtggaaagct tctttcattc actgaaagtg gaatgtctcc atggagaaca
     7261 ctttatcagc cgggaaataa tgcgggcaac ggtgtttaat tatatcgaat gtgattacaa
     7321 tcgctggcga cggcacagtt ggtgtggcgg tctcagtccg gaacaatttg aaaacaagaa
     7381 cctcgcttag agcagtgtcc atattacgag ggtaggatca gttgttctgt ttgagttcta
     7441 tttttgaatc gcacactggc aaataatcca taactaggta aaatccaaaa ataagtcgcg
     7501 taaccgggaa tagagttatc ttgtatttgg ttcataacta catcgggcgc agtaacactt
     7561 gaatgcctca taacagaagc aactcccgct tggttgatgg aacttcattc caaatagtaa
     7621 ctagccaata atcgcctgac ctattgatat taaataagta agtacctaaa taatcactat
     7681 ctgcttgtgg ttcataaagt tttgtgtttt ctatactctt atccgtactc caaaagtgaa
     7741 gatctgtcag gagctcctga agtgagccaa aaacaggagt attattaccc cataagtagt
     7801 atccacattc atgtactcga taaaaactaa gtttaaccga ttcgctcatt ggtcagaagt
     7861 tcccttacct tattattctc aatgggcata attttacatt gtgcaatagt tgctggcgag
     7921 ttaaatggtc acattttctc ccatacgtac atttatggct tcagttaaag cccgctcacg
     7981 cactgaaaac cttgagtgcc ctacagggct ttagggcact caatactgct gctatcagcg
     8041 caacattttt ctaatatttt gatgcgattg tggcagattt gaacgaagaa gatattcatt
     8101 aaaggctata tgagcattag tatgctttga cttatatacg tcgtgttgaa agtcgggtcg
     8161 atcaataaga ccaggataac ttcccactgc aatagaacgg tcattcaaac tcacaatcat
     8221 aggtgcctcc tgagttccct taattatgca ttgaaaacca tccaattcca gacttgccct
     8281 caattgagac aatttttcta cctgaatatc aggtgaagca caacgaggaa ccattccgta
     8341 tagtgcataa cgaagtaaag atgcacctag tttcctatcg agacggcttt gtatatgctg
     8401 gttgtggaaa tgattgagac aatctgtaca ggaggtatcg cactcacagc tttctaacaa
     8461 tgcgagtgtt gcagtaagaa tgtcatctag attcgctgct gctacttccg cataacccgc
     8521 accgccggat aaagtatcat aaaggaagag atccaatgcc tgagtatctt cctctatagt
     8581 gggtaaaatt ctgaaaccag agccaaactc agcaggatca agatccagtt gtttatggcg
     8641 actagctgca agccttagtg cttccgctat tgtatataat gcatcttcat acatccgtaa
     8701 aacgatagca tttgaagtat cagttacaag cggagaccca acggttattc gtaataaaag
     8761 caaatcagta cggaaatcat gtccgagaaa aacgcgttta tactcgccag agcataagcg
     8821 aggcgtttcc ttagttgcta tatatttata cggtctttca tgtgccccct ttgccggtga
     8881 gtaggaatca taaacggagg ccgcaccaca ttcgcaacat actgaaaaac cactggactc
     8941 cccctcattt ttccctcggt tcaccgtcac cagtttctga tctattgcgt gagtaaaaac
     9001 aatatgagca cctccattat tgaacttaaa atcttcagga tcaacaggtt gtggatattg
     9061 tgccgctgtt acataggtga tttcttgctc tctgtcgtcc tcattaagtt ccttggcatt
     9121 ttcaggtcca aagacttcgg gctgaatcat tatttctact tttagaatgc caccacagat
     9181 cggacaagta ttttcgctat tctgattatt atgaggatcg cggacaaaag agcacttatc
     9241 gcaatgaata aactttttgg gattattgaa aagctttctt gcccggttta gttcgccttt
     9301 caatgcatta gaaaaaacac caccagagcg ataggttttc ctatcaataa caatcaaacg
     9361 tcccggggca tattcactca gagcctgaga aattgattgc tgaggctgtt gtactgttcg
     9421 cacctcaaaa gaacctctaa tattctttac aattttttct accaagaaac tacagaggct
     9481 tgtaggaaat gcataacttg gtaataaacc atggtaaaac aggaactcaa gtaattcttc
     9541 ttgtgcaaat ttcattccac cagaagtctg ctcatcatct tcattttcct catcaacaag
     9601 aacggcagtt tgtggaacaa tttcagccag cccatggagt gtatttaaaa attcctctgc
     9661 taccttagca aaccagtcac tggcagaaag ccctccagtt tcaagaacag gaggaagcca
     9721 tgctgcaaca cttgttctca aatcaccatt agtagataga atacggtttt taacccaatt
     9781 attaaagcta tcgagattta ggccagtatc ttttgctcca tgaaaaaaat ctcgtgtagt
     9841 accaagtgct ttctcaagta tggcagtttt ctctgcggga ttataaattc cttgttccat
     9901 taactcgtga aaaaaggtct gaactaaaaa agaatgaacg tgtcttctgg ctattttggg
     9961 attatttact ttcacttcag gtgtacgagg agaacctgca acaatgcgtt caggattaag
    10021 gaaataataa ctatcatgag ggccattttg agaatatgta accaccgttg aaacagatgc
    10081 gccacggcgg cctgctcgcc cagcacgttg ctgataattt tctcgttgcg gagggacgtt
    10141 tcttaaagca acagcaacca gagatccaat atcaaccccc acttccatcg tcgtcgtaca
    10201 actaagtaca tcaatgggct tgtcgttatc attaataaga acatcttgga atctcagttc
    10261 gtagagttct gtagtggcat gaacgctggc cctatctcta tgtgagagtt gagcagtatg
    10321 ctcttcaacg ctaaggttta gaagccgcga atttgaaacc aaaacttctt ctaccggcga
    10381 acgccagaat ccttttcgtg cattaatata gctgctttcc gacggctcga ctgttttgac
    10441 actgttacta ccacaagcaa ggcaagtaga atgttctaaa gcaaatggca ttagtgccgt
    10501 gcagtcatta cattgtttcc agacatgcaa gagatctatt ttcagacgta gtgcatttgg
    10561 agcaagaaag tagacaccat cttttcctaa tgtcagatga gtacgaaaaa tctcctccaa
    10621 aacttccaca taaagctccc ccatagcagg atactgtatc agggttttcc taagagcttt
    10681 tccaaaccgt ccttgactac cccaagtggg tttgtagaat ccagctgctt tgattcgtag
    10741 tgtcgaatca atagattcat caaaagcaaa ttcagtgagt aaggtatcaa tccaagcaac
    10801 agctaaagca tgaacatcct tgctctcaat attgagcttc ttggactgca catcttccca
    10861 catttttttt gatttaagct gcgatggttc aacaaaacca actgttgttc cggaaagaga
    10921 atagtaattg ctacataaaa gtttaagcaa cgctatttta tatcgtgacg gtgactcttg
    10981 ggggctgaag ctatcatcaa aagcttgagc cagatcgcta ttataatcac gataaaattc
    11041 atcacgggcc attacaactt ttcgtgaatc ttccccatca aaaataagca agtcatgttc
    11101 agaaaggact gataggaaag caaggtaaag tactgatgtt ggtttgggtt cccgattgat
    11161 atctttcagt ttagaacagg cgagagcaat ggattgccga aacaaatcaa gctcaatatc
    11221 tctaggaata tcacgtgcaa gccgagctgc tttttgtcgg ccatcagaaa aaataagtac
    11281 tttttttccc ccattgggat gtttaccatc aataggacga ctcgctggct ggtgagatat
    11341 ctgtgtacgt actaacgttg taaaaggtgc ttcccctttt gtaacatgat ccataatttt
    11401 agacggttca ttctgagcac ttcttgtctt acgcatacaa acagggcatt catcaaatgt
    11461 aatttctgat ccagacttaa ctcggtcagg tataaagact ttacgataac cagaatcctc
    11521 atcttgacac tgtttagaaa ggcgtcctgt tgctatatgt agccatctgt cctggtaatc
    11581 actatgtaca tgaggtgttt cctcgaccaa tatatctatg ggaacaagat cgatatcctc
    11641 atcttctgat aatggtccgt tcggctggtg ccatacaaag tccatttcgg aactaacgta
    11701 tccacgaata aaagccgcac cgcagtcacg gtgggtaaat aattcgtaga ctcgcccttt
    11761 tgaagcgcat ttacattgat ccagtggttt cgtataaagg cggccaagta tagttggccc
    11821 gctatggtta cccaaacgtt gattacaatc gggatctata caggcataaa gacctggtaa
    11881 tccccgataa aaaagatgca tgcgagttgg aataagcact ctgccatcgg atgccctctg
    11941 agcatagcaa cccaatgcga gtaatgcatc tgttgctcgc tctgcgattt gctgtggaga
    12001 gtctggaaaa aggttttcac tcaagatatt tagcttaacc gctttacctg aaactatttc
    12061 aataagcgtt tcaataggac caaaaccagt caaattatca aataaccaat tacgtagtgt
    12121 actatgatct tttatcatcg gcttttgcca gcccattcgt tcggcaagag actctattgc
    12181 tgcatatgca gattcaagat cctcagctac gcactgaaat gaatttaggt cgaattcagc
    12241 cagtgcatta gcttctttac tggtaacaat ttgtgactca ggacgcgatt cccttgtacc
    12301 ctcaataatt cgaaatttcc tcgaagaggt tggtgataag ccagttaagt cttgggcaaa
    12361 acgttctcca tcctcaatgg accctagact agcactggta aggatgcagc gcatacgttc
    12421 ccggggaata tccaaccgag cacagaggcg acgtattaaa agggctacct ctgctccccc
    12481 tgctcctcta tacatatgcg cttcatcaag cactaagata agctcattca tctcatcagc
    12541 tttgagccat tccttagtct gctcaaaaat attacgctcg ataggtcgca tcagcatata
    12601 ctcaagcatg gagtagttcg ttatcagtaa ttctggacag cgattctgta tttcatgccg
    12661 ggtcattagc tcacgatcct caggctgggt aattagcctc tccccccaat tgttcaaaac
    12721 aaattgctta cccgtttttt tgcctgagac gtaggtttta gcctgagatg cgctttgccc
    12781 ataaaaagca tcaagatctt tacttggcca gcgaccaatg cggttcagtt ccgcacgtac
    12841 gggggcgtta tttgcgagtt tattgtaaaa ctcatcgaaa aggggtttga taaaaagctc
    12901 gtctcgtcta gagctacgac gaccagggta aggcgttctt cccgtataag cgccaaagcg
    12961 tacaggggca catcttccag atctcagtat tttagaggct tcagaatcac caaaaagacg
    13021 tctgatacga gcaagttgat cgttaactaa tgcattcatt ggatataata aaattgctct
    13081 acaacctgga agggatgcag atttaggtct ctcggaagat tcaatcgcca attttccaat
    13141 aattggcatt agaaagcttt cagtcttacc ggagcctgta cctgttgcaa tgaccagatc
    13201 agaagcgttt tcgccaagaa atgactcaag tgcctgtgat tggtgtttat aggggcgttg
    13261 atagaggcca attccaagtt ctgatagttg agttagcaca ttacttgctg cttcgggaat
    13321 aggcaattca ctgtatggcg caccaggttc ataaattggg gttgcttcta tataaggagc
    13381 ttgagcaata gtttcatttt gctgtaaaag cgctcgtcgc tcagcaatta acccttcatc
    13441 ccggatatga tattgtgcct caatgtattt tctcagattt tcactaaggc ttttcacggt
    13501 atcatgtata cctgaacgtt cagttacttt atttttatta atcatatttc attccgtcgc
    13561 gtgaattcgt taatccaaat aataccaagc ccttcaaaag cgctacgcac tatgggtaat
    13621 atttcctcgg ggaatacatg gtgtgttatt cctgaatgtt cattttcaaa acctgattct
    13681 ctccagccta gcaggagtac cttcgtttct cgtcttggta atcttctggt taatcttaat
    13741 cttgctagcc cattagatat tttgatacgg acctttagcg gacaattatc ttttgtatcg
    13801 agaaaaaaac gtaatcttct gacatcatca gacgattcta acgaattcat tctacataag
    13861 cgtccagctt caatttctcc taaataatag gaaaagtgat tatcaacgga cattctgcat
    13921 aagtagattt gctttttatt aaaagaaagt tctgacaaat ggagccattt tccccgcaca
    13981 tatgcagtcg tttcactcat attgccaggt gcatcgataa agccggaaat agttccagat
    14041 agtagtctgg atgaccattc ttcattgcct tctgctgggg caccaatcca ctcatttgca
    14101 tcccagattt caacacttcc agtacacact ttttcttcaa ccaagcgaac tcttccagca
    14161 gatttagcta ccacgcccgt tgaaaatgta caggaaggct ctccaccaaa aaaaacagcc
    14221 atcttattgt caattcgtac tgcatgtggg ggagctgtta gccaattacc accttctaac
    14281 ttaatcatgt cacccaattc agccaagctg ttcaatatag acataatgcc tggatgtata
    14341 gcattatcaa tatcagcaat gtctggccat aaaggtacca attttcgcct tactgcacta
    14401 gtgagtcgaa gcgaggttac agtttgccta gcttcttctg tttcagatat agaatattga
    14461 tataatacgc tccttaagca ttctgaaact gctgaaattc tcaacccttc atcatcaaat
    14521 cgacaattta atgcagttga taacatatcc agtgctttgt ctcgtgatac tgctctccac
    14581 tccattaacc acctcctcaa gaagatattt ttgcactata attttttaat tcacgattgg
    14641 caatatcttc tatcttttgg acggggccac ctttaatttt tgcccatgta agagtataaa
    14701 aagacaagac agaataaaga tcataaatat aatttccatt agggatcctt atgagtgaag
    14761 tatagaaaat atgaatcatt ctcttccaca aagttccccc atcaaatcca gcttcgtcca
    14821 gtaatgctct taattcatct acataatcat caacactatc aagatgtagt ccatcaatat
    14881 ttgtccattt atccttggca agacaacctg gtttcaattg gggtaaagta gctgataaac
    14941 cacgcatttt taatgtatca gtatcaataa caggtcccaa ctcggccaac attcctccat
    15001 cagggaatgt agctgggcct tgtttccagg tagctatcaa tgccagatgg tcataatttg
    15061 ttggatgtat ttgccgttga acaactatat ctctaattgc cgctccataa atctcaaatg
    15121 ctgaaagatt ggcccctttc aaaaggagac agcgagatga ttcagctata gtctctataa
    15181 aatcaaaagc atccatgtca gaaataatac caactggaac tctccatatg tgataacgtg
    15241 gtgcaccaat agcaatggca attgcatccg cgataatatc tgccaaagag ccactgaatt
    15301 gaatgatttg tccagaaacg aaggtagcta atgtcaatct agccaatttt tctgctgaat
    15361 tttttgtcaa tccaacagcc tgtaaattta aagaaattct attagatatg tcttcggagg
    15421 atgaaagata ctcataattt tcatagtgcg ctatttcatg gaattttgta aatctattgg
    15481 tgacactcac ttcgctagct tgagatgtgt ttatttcaag tgtatctatt cgttc
//
LOCUS       DAPGUL010000104        15479 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.106, whole genome shotgun sequence.
ACCESSION   DAPGUL010000104 DAPGUL010000000
VERSION     DAPGUL010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15479
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.106"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(84..431)
                     /gene="trbA"
                     /locus_tag="RHX21_003521"
     CDS             complement(84..431)
                     /gene="trbA"
                     /locus_tag="RHX21_003521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbA"
                     /protein_id="HDV1988659.1"
                     /translation="MSEDYLKMFTGVVLLIFVIIAGYFFSERNDRKMFLLSSLVFLVI
                     NIACLYVLTASLWFLCGAIMSQGAALVVSIVAAALPDVTSFDRFRRIFICIVLSSVWS
                     GVMWFFIRGLMTG"
     gene            complement(447..1190)
                     /gene="traF"
                     /locus_tag="RHX21_003522"
     CDS             complement(447..1190)
                     /gene="traF"
                     /locus_tag="RHX21_003522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly protein TraF"
                     /protein_id="HDV1988660.1"
                     /translation="MNKALLPLLLCCFIFPASGKDAGWQWYNEKINPKEKENKPVPAA
                     PRQEPDIMQKLAALQTATKRALYEAILYPGVDNFVKYFRLQNYWTQQAGLFTMSARKA
                     MLAHPELDYNLQYSHYNGTVRNQLAADQAQQRQAIAKLAEHYGIMFFYRGQDPIDGQL
                     AQVINGFRDTYGLSVIPVSVDGVINPLLPDSRTDQGQAQRLGVKYFPAMMLVDPKQGS
                     VRPLSYGFISQDDLAKQFLNVSEDFKPNF"
     gene            complement(1183..1440)
                     /gene="trbE"
                     /locus_tag="RHX21_003523"
     CDS             complement(1183..1440)
                     /gene="trbE"
                     /locus_tag="RHX21_003523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbE"
                     /protein_id="HDV1988661.1"
                     /translation="MKVIFTSNRFIDFLIRLLITAIVISPVIIWSWDTVKETTADGML
                     AAAFVILYSGVLLFILYFCFSALTDLQKPDERKSDERNEDE"
     gene            complement(1467..3275)
                     /gene="traN"
                     /locus_tag="RHX21_003524"
     CDS             complement(1467..3275)
                     /gene="traN"
                     /locus_tag="RHX21_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001756807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system mating-pair
                     stabilization protein TraN"
                     /protein_id="HDV1988662.1"
                     /translation="MKRILPLILALVAGMAQADSNSDYRAGSDFAHQIKGQGSSSIQG
                     FKPQESIPGYNANPDETKYYGGVTAGGDGGLKNDGTTEWATGETGKTITESFMNKPKD
                     ILSPDAPFIQTGRDVVNRADSIVGNTGQQCSAQEISRSEYTNYTCERDLQVEQYCTRT
                     ARMELQGSTTWETRTLEYEMSQLPAREVNGQYVVSITSPVTGEIVDAHYSWSRTYLQK
                     SVPMTITVLGTPLSWNAKYSADASFTPVQKTLTAGVAFTSSHPVRVGNTKFKRHTAMK
                     LRLVVRVKKASYTPYVVWSESCPFSKELGKLTKTECTEAGGNRTLVKDGQSYSMYQSC
                     WAYRDTYVTQSADKGTCQTYTDNPACTLVSHQCAFYSEEGACLHEYATYSCESKTSGK
                     VMVCGGDVFCLDGECDKAQSGQSNDFAEAVSQLAALAAAGKDVAALNGVDVRAFTGQA
                     KFCKKAAAGYSNCCKDSGWGQDIGLAKCSSDEKALAKAKSNKLTVSVGEFCSKKVLGV
                     CLEKKRSYCQFDSKLAQIVQQQGRNGQLRISFGSAKHPDCRGITVDELQKIQFNRLDF
                     TNFYEDLMNNQKIPDSGVLTQKVKEQIADQLKQAGQ"
     gene            complement(3272..3910)
                     /gene="trbC"
                     /locus_tag="RHX21_003525"
     CDS             complement(3272..3910)
                     /gene="trbC"
                     /locus_tag="RHX21_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001553832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly protein TrbC"
                     /protein_id="HDV1988663.1"
                     /translation="MKLSMKSLAALLMMLNGAVMASENVNTPENRQFLKQQENLSRQL
                     REKPDHQLKAWAEKQVLENPLQRSDNHFLDELVRKQQASQDGKPRQGALYFVSFSIPE
                     EGLKRMLGETRHYGIPATLRGMVNNDLKTTAEAVLSLVKDGATDGVQIDPTLFSQYGI
                     RSVPALVVFCRQGYDIIRGNLRVGQALEKVAATGDCRQVAHDLLAGKGDSGK"
     gene            complement(3919..4911)
                     /locus_tag="RHX21_003526"
     CDS             complement(3919..4911)
                     /locus_tag="RHX21_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer pilus assembly protein TraU"
                     /protein_id="HDV1988664.1"
                     /translation="MKRSLWLLMLFLLAGHVPAASADSACEGRFVNPITDICWSCIFP
                     LSLGSIKVSQGKVPDTANPSMPIQICPAPPPLFRRIGLAIGYWEPMALTDVTRSPGCM
                     VNLGFSLPAFGKTAQGTAKKDEKQVNGAFYHVHWYKYPLTYWLNIITSLGCLEGGDLD
                     IAYLSEIDPTWTDSSLTTILNPEAVIFANPIAQGACAADAIASAFNMPIDTLFWCAGS
                     QGSMYPFNGWVSNESSPLQSSLLVSERMAFKLHRQGMIMETIGKNNAVCNEYPSPILP
                     KERWRYQMVNMYPDSGQCHPFGRSVTRWETGKNPPNTKKNFGYLMWRKRNCVFL"
     gene            complement(4908..5540)
                     /gene="traW"
                     /locus_tag="RHX21_003527"
     CDS             complement(4908..5540)
                     /gene="traW"
                     /locus_tag="RHX21_003527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system protein TraW"
                     /protein_id="HDV1988665.1"
                     /translation="MRCRGLIALLVWGQSVAAADLGTWGDLWPVKEPDMLTVIMQRLT
                     VLEQSGEMGRKMDAFKERVIRNSLRPPAVPGIGRTEKYGSRLFDPSVRLAADIRDNEG
                     RVFARQGEVMNPLQYVPFNQTLYFINGDDPAQVAWMKRQTPPTLESKIILVQGSIPEM
                     QKALDSRVYFDQNGVLCQRLGIDQVPARVSAVPGNRFLKVEFIPAEEGRK"
     gene            complement(5537..5923)
                     /gene="trbI"
                     /locus_tag="RHX21_003528"
     CDS             complement(5537..5923)
                     /gene="trbI"
                     /locus_tag="RHX21_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system protein TrbI"
                     /protein_id="HDV1988666.1"
                     /translation="MSSTQKPADVTAERRSHWWWTVPGCLAMVLLNAAVSYGIVRLNA
                     PVTVAFNMKQTVDAFFDSASQKQLSEVQSKALSARFNTALEASLQAWQQKHHAVILVS
                     PAVVQGAPDITREIQQDIARRMRAEP"
     gene            complement(5920..8547)
                     /gene="traC"
                     /locus_tag="RHX21_003529"
     CDS             complement(5920..8547)
                     /gene="traC"
                     /locus_tag="RHX21_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein TraC"
                     /protein_id="HDV1988667.1"
                     /translation="MNNPLEAVTQAVNSLVTALKLPDESAKANEVLGEMSFPQFSRLL
                     PYRDYNQESGLFMNDTTMGFMLEAIPINGANESIVEALDHMLRTKLPRGVPFCIHLMS
                     SQLVGDRIEYGLREFSWSGEQAERFNAITRAYYMNAAATQFPLPEGMNLPLTLRHYRV
                     FFSYCSPSKKKSRADILEMENLVKIIRASLQGASITTQAVDAQAFIDIVGEMINHNPD
                     SLYPKRRQLDPYSDLNYQCVEDSFDLKVRADYLTLGLREKGRNSTARILNFHLARNPE
                     IAFLWNMADNYSNLLNPELSISCPFILTLTLVVEDQVKTHSEANLKYMDLEKKSKTSY
                     AKWFPSVEKEAKEWGELRQRLGSGQSSVVSYFLNITAFCKDNNETALEVEQDILNSFR
                     KNGFELISPRFNHMRNFLTCLPFMAGKGLFKQLKEAGVVQRAESFNVANLMPLVADNP
                     LTPAGLLAPTYRNQLAFIDIFFRGMNNTNYNMAVCGTSGAGKTGLIQPLIRSVLDSGG
                     FAVVFDMGDGYKSLCENMGGVYLDGETLRFNPFANITDIDQSAERVRDQLSVMASPNG
                     NLDEVHEGLLLQAVRASWLAKKNRARIDDVVDFLKNARDNDQYVESPTIRSRLDEMIV
                     LLDQYTAGGTYGRYFNSDEPSLRDDAKMVVLELGGLEDRPSLLVAVMFSLIIYIENRM
                     YRTPRNLKKLNVIDEGWRLLDFKNHKVGEFIEKGYRTARRHTGAYITITQNIVDFDSD
                     KASSAARAAWGNSSYKIILKQSAKEFAKYNQLYPDQFLPLQRDMIGKFGAAKDQWFSS
                     FLLQVENHSSWHRLFVDPLSRAMYSSDGPDFEFVQQKRKEGLSIHEAVWQLAWKKSGP
                     EMASLEAWLEEHEKYRSVA"
     gene            complement(8707..8928)
                     /gene="traR"
                     /locus_tag="RHX21_003530"
     CDS             complement(8707..8928)
                     /gene="traR"
                     /locus_tag="RHX21_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraR"
                     /protein_id="HDV1988668.1"
                     /translation="MSDEADEAYSVTEQLTMTGINRIRQKINAHGIPVYLCEACGNPA
                     PEARRKIFPGVTLCVECQAYQERQRKHYA"
     gene            complement(9063..9578)
                     /gene="traV"
                     /locus_tag="RHX21_003531"
     CDS             complement(9063..9578)
                     /gene="traV"
                     /locus_tag="RHX21_003531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system lipoprotein
                     TraV"
                     /protein_id="HDV1988669.1"
                     /translation="MKQISLFIPLLGTLLLSGCAGTNTEFECNATTSDTCMTMEQANE
                     KAKKLEQSSEAKPVAASLPRLGEGNFRTMPVQTVTAATPSGSRPAVTAHPEQKLLAPR
                     PLFTAAREVKTIVPVSSVAPVTPPRPLRTGEQTAALWIAPYIDNQDVYHQPSSVFFVI
                     KPSAWGKPRIN"
     gene            complement(9575..9826)
                     /gene="trbG"
                     /locus_tag="RHX21_003532"
     CDS             complement(9575..9826)
                     /gene="trbG"
                     /locus_tag="RHX21_003532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbG"
                     /protein_id="HDV1988670.1"
                     /translation="MNKLVSDGSVKKIKYPVLYESGITPPLCEVSVPEPDAGGKRIVA
                     YVYKSSRNTVFENPDIVKTCTVRDLKNDFVNCDEKGEGQ"
     gene            complement(9819..10187)
                     /locus_tag="RHX21_003533"
     CDS             complement(9819..10187)
                     /locus_tag="RHX21_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011478094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2689 domain-containing protein"
                     /protein_id="HDV1988671.1"
                     /translation="MFISLMTEQSETTEIKMNMRNINVITARSVPDKSVSDDLMHAVL
                     SNCTTRIVLPAPKEFSSESLPHNFNMAAVGVMKKGMSMSLFSSPGHIVVAGQSGSGKS
                     VPVKELIDRIIQKYKEPFDE"
     gene            complement(10126..10707)
                     /locus_tag="RHX21_003534"
     CDS             complement(10126..10707)
                     /locus_tag="RHX21_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001438629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraP"
                     /protein_id="HDV1988672.1"
                     /translation="MPARRAEMAGDALTFRVAFVVRWLLWVVRFVVIWPLATMALMAL
                     FVLWKDNTTPGKLLVQEIDFVRQTAPAGQFPVRECLPSLHDLPGAEEKICRYRAADAA
                     DYVRETDRSLMQLVTAFWATLALMYMSFAAGTGKYPVRPGKMKCVRVATADERLKEVL
                     AEDTSLPGKIRECHVYFPDDRTIRNNGDKNEHA"
     gene            complement(10676..12127)
                     /locus_tag="RHX21_003535"
     CDS             complement(10676..12127)
                     /locus_tag="RHX21_003535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraB"
                     /protein_id="HDV1988673.1"
                     /translation="MASINTIVKRKQYLWLGIVVVGAASAIGGALYLSDVDMSGNGET
                     VAEQEPVPDMTGVVDTTFDDKVRQHATTEMQVTAAQMQKQYEEIRRELDVLNKQRGYD
                     QRRIEKLGQDNAALAEQVKALGANPVTATGEPVPQTPASPPGPEGEPQPGNTPVSFPP
                     QGSVAVPPPTAFYPGNGVTPPPQVTYQSVPVPNRIQRKVFTRNEGKQGPSLPYIPSGS
                     FAKAMLIEGADANASVTGNESTVPMQLRITGLVEMPNSKTYDATGCFVGLEAWGDVSS
                     ERAIVRTRNISCLKDGKTIDMPIKGHVSFRGKNGIKGEVVMRNGKILGWAWGAGFVDG
                     IGQGMERASQPAVGLGATAAYGAGDVLKMGIGGGASKAAQTLSDYYIKRAEQYHPVIP
                     IGAGNEVTVVFQDGFQLKTVEEMALEQSQSTAEEGNPESPVPNPPSAESHLNGFNTDQ
                     MLKQLGNLNPQQFMSGDKNPLGGDAGKEGGNGG"
     gene            complement(12127..12831)
                     /gene="traK"
                     /locus_tag="RHX21_003536"
     CDS             complement(12127..12831)
                     /gene="traK"
                     /locus_tag="RHX21_003536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003982266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system secretin
                     TraK"
                     /protein_id="HDV1988674.1"
                     /translation="MFGSLFFSCSVMAANGTLAPTVVPMVNGGQASIAISNTSPNLFT
                     VPGDRIIAVNSLDGALTNNEQTASGSVVVATVNKKPFTFILETERGLNLSIQAVPREG
                     AGRTIQLVSDLRGTGEEAGAWETSTPYESLLVTISQAVRGGKLPAGWYQVPVTKETLQ
                     APAGLSSVADAVWTGNHLKMVRFAVENKTLSALSIRESDFWQPGTRAVMFSQPASQLL
                     AGARMDVYVIRDGEGN"
     gene            complement(12842..13408)
                     /gene="traE"
                     /locus_tag="RHX21_003537"
     CDS             complement(12842..13408)
                     /gene="traE"
                     /locus_tag="RHX21_003537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraE"
                     /protein_id="HDV1988675.1"
                     /translation="MEHGARLSTSRVMAIAFIFMSVLIVLSLSVNVIQGVNNYRLQNE
                     QRTAVTPMAFNAPFAVSQNSADASYLQQMALSFIALRLNVSSETVDASHQALLQYIRP
                     GAQNQMKVILAEEAKRIKNDNVNSAFFQTSVRVWPQYGRVEIRGVLKTWIGDSKPFTD
                     IKHYILILKRENGVTWLDNFGETDDEKK"
     gene            complement(13430..13741)
                     /gene="traL"
                     /locus_tag="RHX21_003538"
     CDS             complement(13430..13741)
                     /gene="traL"
                     /locus_tag="RHX21_003538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system protein
                     TraL"
                     /protein_id="HDV1988676.1"
                     /translation="MSGDENKLKKYRFPETLTNQSRWFGLPLDELIPAAICIGWGITT
                     SKYLFGIGAAVLVYFGIKKLKKGRGSSWLRDLIYWYMPTALLRGIFHNVPDSCFRQWI
                     K"
     gene            complement(13746..14108)
                     /gene="traA"
                     /locus_tag="RHX21_003539"
     CDS             complement(13746..14108)
                     /gene="traA"
                     /locus_tag="RHX21_003539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005771228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system pilin TraA"
                     /protein_id="HDV1988677.1"
                     /translation="MNAVLSVQGASAPVKKKSFFSKFTRLNMLRLVRAVLPAAVLMMF
                     FPQLAMASGSQDLMASGNSTVKATFGKDSSVVKWVVLAEVLVGAVMYMMTKNVKFLAG
                     FAIISVFIAVGMAVVGLK"
     gene            complement(14141..14536)
                     /gene="traY"
                     /locus_tag="RHX21_003540"
     CDS             complement(14141..14536)
                     /gene="traY"
                     /locus_tag="RHX21_003540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001366159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer relaxosome protein TraY"
                     /protein_id="HDV1988678.1"
                     /translation="MKRFGTRSATGKMVKLKLPLDVESLLIEASNRSGRSRSFEAVIR
                     LKDHLHRYPKFNRAGNIYGKSLVKYLTMRLDDETNQLLIAAKNRSGWCKTDEAADRVI
                     DHLIKFPDFYNSEIFREADKEEDITFNTL"
     gene            complement(14635..15324)
                     /gene="traJ"
                     /locus_tag="RHX21_003541"
     CDS             complement(14635..15324)
                     /gene="traJ"
                     /locus_tag="RHX21_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003979562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer transcriptional regulator
                     TraJ"
                     /protein_id="HDV1988679.1"
                     /translation="MYPMDRIQQKHARQIDLLENLTAVIQDYPNPACIRDETGKFIFC
                     NTLFHESFLTQDQSAEKWLLSQRDFCELISVTEMEAYRNEHTHLNLVEDVFIQNRFWT
                     ISVQSFLNGHRNIILWQFYDAAHVRHKDSYNQKTIVSDDIRNIIRRMSDDSSVSSYVN
                     DVFYLYSTGISHNAIARILNISISTSKKHASLICDYFSVPNKDELIILLYNKKFIHYL
                     YEKAMCIINTR"
BASE COUNT         3660 a         4270 c         3637 g         3912 t
ORIGIN      
        1 ctggattgcg gtatggttta tcatatggtc ttcagtaatc aacctcatta ttttgtatgg
       61 tttttatgac cgttttatat gacttagcct gtcataagcc cccttataaa aaaccacatc
      121 actccggacc ataccgatga caacacaata cagataaata ttcttctgaa cctgtcgaag
      181 ctcgtaacgt ccggtaatgc ggccgcaact attgaaacaa ccagtgctgc gccctgactc
      241 ataattgcac cacacagaaa ccagagactg gcggtaagca catataaaca cgcgatatta
      301 ataacaagga aaaccagtga gctcaggaga aacattttcc tgtcattacg ctcagaaaag
      361 aaataaccgg caataatgac aaatattaac agaacaacac ctgtaaacat tttcaaataa
      421 tcttcactca taaatcaaat ccgcgattaa aaattgggtt taaaatcttc agaaacgttc
      481 aggaactgtt ttgccaggtc gtcctgcgaa ataaagccgt atgataacgg gcgaacactg
      541 ccctgtttcg ggtcaaccag catcatggcc gggaaatatt tcacgccgag gcgctgcgcc
      601 tgcccctggt cagtccggga atccggcaac agcggattaa tcacgccatc cacggaaacg
      661 ggaataacac tcagaccata cgtatcccgg aagccattaa tgacctgcgc cagttgcccg
      721 tcgatggggt cctgcccccg gtaaaaaaac atgatgccgt agtgttcagc cagtttcgca
      781 atggcctgtc gctgctgcgc ctggtctgct gccagctggt tccgtaccgt gccgttgtaa
      841 tggctgtact gcaggttata gtccagttca ggatgtgcca gcatggcctt tctggcgctc
      901 atggtgaaaa gcccggcctg ctgagtccag taattttgca gccggaaata tttcacaaaa
      961 ttatccacgc cgggatacag aatggcttcg tacagcgccc gctttgttgc cgtctgcagt
     1021 gcggccagtt tctgcataat atccggttcc tgacgggggg ctgcaggtac aggtttattt
     1081 tctttttcct tcggatttat tttctcgtta taccactgcc agcctgcatc ttttcctgac
     1141 gccggaaaaa taaagcagca gagtaacagt ggcagtaatg ctttattcat cttcattcct
     1201 ttcatcactt tttctttcat caggtttctg caggtcagtc agggcagaaa aacaaaaata
     1261 cagaataaac aggagcacac cggagtaaag gataacgaaa gcagcggcaa gcatcccgtc
     1321 tgccgtggtt tcttttaccg tatcccacga ccagataatt accggagaaa tgacaatcgc
     1381 tgtaatcaaa agccggataa gaaaatcaat aaaacggttc gacgtgaata tgactttcat
     1441 catttccccc ggttatttcc cataccttac tgtcctgcct gtttcagctg gtcagcaatc
     1501 tgctctttca ctttctgcgt cagaacgcca ctgtccggga ttttctggtt attcatcagg
     1561 tcttcgtaga agttagtgaa atccagtctg ttgaactgaa ttttctgcag ctcatcaacc
     1621 gtaatccccc gacagtcagg atgcttcgca ctaccaaaac tgatacgcaa ctgaccgttg
     1681 cgcccctgct gctggactat ctgcgccagc ttcgaatcaa actgacagta gctgcgtttt
     1741 ttctccagac agacacccag cactttcttc gaacagaact ccccgacgct gacggtcagt
     1801 ttgtttgatt ttgctttagc cagggccttt tcatcactgc tgcatttggc cagcccgata
     1861 tcctgtcccc agccgctgtc cttacagcag ttgctgtatc cggctgcagc cttcttacaa
     1921 aatttcgcct gaccggtgaa agcacggaca tccaccccgt tcagcgccgc aacatcctta
     1981 cctgctgcgg ccagtgccgc cagctgagaa acggcttcgg caaaatcatt actctgcccg
     2041 ctctgagcct tatcgcattc gccatcgaga cagaagacgt ctcccccaca gaccatcact
     2101 ttcccggatg tttttgactc acaggagtac gtggcatatt catgcagaca ggcaccttct
     2161 tcggagtaaa aggcacactg gtgtgacacc agggtacagg caggattgtc ggtgtaggtc
     2221 tgacaggttc ccttgtctgc tgactgcgtg acatacgtgt cccggtatgc ccagcagctc
     2281 tggtacatgc tgtatgactg accgtctttc accagcgtcc tgttcccgcc agcctccgta
     2341 cattctgttt ttgtcagttt ccccagctcc ttgctgaacg ggcagctttc agaccagaca
     2401 acatacgggg tgtacgaggc tttttttacc ctgacaacca gacgcagctt cattgccgta
     2461 tgacgtttga attttgtatt cccgacccgg acggggtgag atgacgtaaa agccacaccg
     2521 gcagtcagtg ttttctgtac tggtgtaaat gaggcatctg ctgagtattt ggcattccag
     2581 ctcagtgggg ttcccagtac tgtaattgtc ataggtacac tcttctgcag gtaagtacga
     2641 ctccagctgt aatgcgcatc gacaatttca ccggtaacgg gagaggtaat ggagacaaca
     2701 tactgaccat tcacttcacg tgcaggtagc tgactcattt catactccag cgtccgggtt
     2761 tcccatgtgg tactcccctg cagctccata cgggcagttc gtgtgcagta ctgctccacc
     2821 tgtaaatccc gctcacaggt gtaattcgtg tattcactcc ggctaatctc ctgcgcactg
     2881 cactgctgcc cggtgtttcc cacaatgctg tcagcccggt tcaccacatc cctgccggtc
     2941 tggataaacg gtgcatccgg tgaaagaatg tctttcggct tgttcatgaa tgactctgta
     3001 atggtttttc cggtttcacc ggtcgcccat tccgtggtgc cgtcattttt caggccgcca
     3061 tccccgccgg cagtcacgcc accgtaatat tttgtctcgt ccggattcgc gttatagccg
     3121 gggatactct cctgtggctt aaagccctga atactgctgc ttccctgtcc tttgatctgg
     3181 tgagcaaaat cagagccggc ccggtaatca ctgttgctgt cagcctgtgc catgccggca
     3241 accagagcca gtatcagagg taaaatacgt ttcatttccc ggaatctcct ttccctgcca
     3301 gtaaatcatg agccacctgc cggcagtcac ccgtggcggc cactttctcc agcgcctggc
     3361 cgacccgcag gtttccccgg atgatgtcgt atccctgacg gcagaacacc accagtgccg
     3421 gtacactgcg aatgccgtac tgtgaaaaca gcgtcgggtc gatctgaaca ccatcagttg
     3481 cgccgtcttt caccagggac aacacggctt cagcggtggt cttcaggtca ttattcacca
     3541 tgccccgcag tgtggccgga ataccgtagt gccgggtttc gcccagcatc cgtttcagcc
     3601 cctcttcggg aatggaaaac gacacaaaat acagggcacc ctgccggggt ttcccgtcct
     3661 gtgaagcctg ctgtttacga accagctcat ccaggaaatg gttatctgaa cgctgaaggg
     3721 ggttttccag cacctgcttc tccgcccagg ctttcagctg atggtcaggt ttttcacgca
     3781 gttgtctgct taaattttcc tgctgcttca ggaactggcg gttttcaggt gtgttcacat
     3841 tttctgacgc cataaccgcc ccgttcagca tcatcagcag tgctgccaga gatttcatac
     3901 tcagcttcat cattcacctc acaggaagac acagttacgt ttacgccaca tcaggtagcc
     3961 gaagtttttc tttgtgttgg gcggattttt cccggtttcc cagcgggtca cgctgcgccc
     4021 gaacgggtgg cactgcccgc tgtccggata catattcacc atctggtaac gccagcgttc
     4081 tttgggcagg attggggacg gatattcatt acagacggcg ttatttttcc cgatggtttc
     4141 cataatcatg ccctgacggt gcagcttgaa cgccatgcgt tcactgacca gcagggagga
     4201 ctgcaacgga ctggactcat tactcaccca gccattgaac gggtacatac ttccctgcga
     4261 accggcacac cagaacagag tatcgatggg catgttaaag gcgctggcaa tggcatctgc
     4321 agcacaggcc ccctgtgcta tcggattggc aaaaatgacg gcttccggat tgagaatggt
     4381 ggtcaggctg ctgtccgtcc aggtggggtc gatttcagaa agataagcga tatccaggtc
     4441 accaccttcc aggcagccca gcgatgtgat gatgttaagc cagtacgtca gcgggtattt
     4501 gtaccagtga acgtgataga acgctccgtt cacctgcttc tcatcttttt tcgccgttcc
     4561 ctgtgccgtt ttaccaaaag ccggcaggct gaagcccagg ttcaccatac atcccggtga
     4621 ccgggtgacg tccgtcagcg ccatcggctc ccagtaacca atggccagtc cgatacgcct
     4681 gaacagcggc ggcggtgccg gacaaatctg aatgggcatc gacgggttcg ccgtgtcggg
     4741 gaccttaccc tgactgactt tgatactgcc cagcgagagc gggaaaatac agctccagca
     4801 gatatccgtg atcgggttta caaaacgccc ctcacaggca gaatccgcag acgccgcagg
     4861 gacatgaccg gcgagaagga ataacatcag cagccacagg cttcgcttca ttttctgccc
     4921 tcctctgccg gaataaattc caccttcagg aagcgattgc cgggaacggc gctcacccgt
     4981 gccggtacct gatcgatgcc gaggcgctgg cagagcacac cgttctggtc aaagtaaaca
     5041 cggctgtcca gtgctttctg catctccggg atactgccct gcaccaggat aattttgctc
     5101 tccagtgtgg gcggcgtctg gcgtttcatc caggcaacct gcgccggatc atcgccattg
     5161 atgaaataca gcgtctggtt aaaaggaaca tactgcagcg gattcatcac ttcaccctgg
     5221 cgggcaaaca cccgcccttc gttatcccgg atatccgcag ccagtctgac ggacgggtca
     5281 aacaaccggc tgccgtattt ctccgtgcgt ccgataccgg gcacggcagg gggccgcaga
     5341 ctgttgcgga tcacccgctc cttaaaggca tccattttcc ggcccatctc accggactgc
     5401 tccagtaccg tcaggcgctg catgatcacc gtcagcatgt ccggctcctt taccggccac
     5461 agatcgcccc aggtgccaag atcggcggcg gccacactct gcccccatac cagcagggca
     5521 atcagccccc gacatctcat ggttctgccc tcattcgccg ggcaatatcc tgctggattt
     5581 cccgggtgat atccggtgcc ccctgtacca cagcaggcga caccagaatg accgcgtggt
     5641 gtttctgctg ccacgcctgc aggctggctt ccagtgccgt gttaaaacgc gctgaaaggg
     5701 cttttgactg tacttctgac agttgtttct gactggcgct gtcaaaaaac gcatctacgg
     5761 tctgtttcat gttgaaggcg acagtcaccg gtgcgttcag tctgacaatg ccgtaactga
     5821 cagctgcgtt cagtaacacc attgccagac aacctggcac cgtccaccac cagtggctgc
     5881 gtcgttctgc cgtgacgtcg gcgggtttct gcgttgaact catgcaacac tcctgtattt
     5941 ctcatgttct tccagccagg cttccagcga agccatctcc ggccctgact tcttccacgc
     6001 cagctgccac accgcctcat gaatactcag cccctcttta cgtttctgct gcacaaactc
     6061 aaaatccggg ccgtcagagc tgtacatggc gcggcttaac gggtccacaa acaggcggtg
     6121 ccaggaggaa tggttttcca cctgcagcag gaaggaactg aaccactgat ctttggccgc
     6181 accgaactta ccaatcatgt cacgctgcag tggcaggaac tggtccggat acagctggtt
     6241 gtatttcgcg aactccttcg cactctgttt gaggataatt ttgtaggagg agttacccca
     6301 tgccgcgcgg gcagcactgg aggccttgtc agagtcaaag tcgacgatgt tctgtgtgat
     6361 ggtgatatag gcaccggtat gacggcgggc ggtacggtaa cctttctcaa taaactcacc
     6421 gaccttgtga tttttgaagt ccagcagacg ccatccctca tcaatgacgt tcagtttttt
     6481 gaggttacgc ggcgtgcggt acatcctgtt ctcgatgtaa ataatgaggc tgaacatcac
     6541 cgcaaccagc agtgacggac ggtcttccag tccgcccagc tccagcacca ccattttcgc
     6601 atcatcccgc agggacggct catcagagtt aaaataccgg ccgtaagtgc cgccggcggt
     6661 atattgatcc agcaggacaa tcatttcatc cagacggctg cggatggtcg gtgactcgac
     6721 atactggtcg ttatcacggg cgtttttcag gaaatccacc acatcatcga tgcgcgccct
     6781 gttcttttta gccagccagg aggccctgac cgcctgcagc agcagacctt catgcacttc
     6841 atccaggtta ccgttggggc tggccatcac cgacaactgg tcacggacac gctccgctga
     6901 ctggtcaata tcggtgatgt tcgcaaacgg gttaaaacgc agggtttcac cgtccagata
     6961 caccccgccc atgttctcac acagggactt atatccatcc cccatgtcaa acaccacggc
     7021 aaagcccccg gagtccagca cgctgcggat aaggggctgt atcagtccgg ttttaccggc
     7081 cccggaggtg ccacagaccg ccatgttgta gttggtgtta ttcatccccc ggaagaaaat
     7141 atcgataaac gccagctggt tacggtaggt gggtgccagc agacctgccg gtgtcagggg
     7201 gttatccgcc actaacggca tcaggttggc cacattaaag ctctctgcgc gctgaaccac
     7261 accggcctct ttcagctgtt taaacagccc tttcccggcc ataaagggaa ggcaggtcag
     7321 gaaattacgc atgtggttaa agcgcggtga aatcagctca aaaccgtttt tacggaagct
     7381 gttcaggatg tcctgctcca cttccagcgc cgtttcatta ttgtccttgc agaatgctgt
     7441 gatgttgagg aagtaggaca cgacagagga ctgaccggag cccagccgct gacgcagttc
     7501 cccccactcc ttcgcctctt tctccacgga cggaaaccat ttggcatagg aggtcttcga
     7561 ctttttctcc aggtccatgt acttcaggtt ggcttcgctg tgggttttca cctggtcttc
     7621 caccaccaga gtcagcgtca ggatgaacgg acaggagatg gacagttccg ggttcagcag
     7681 gttgctgtag ttgtcggcca tgttccacag gaaggcgatt tccgggttac gggccagatg
     7741 gaaattcagg atgcgggccg tgctgttcct gcccttctca cgcaggccca gcgtcaggta
     7801 atccgcccgg actttcaggt caaaactgtc ctccacacac tgataattca gatcagaata
     7861 cgggtccagc tgacgtcttt tcggatacag ggagtccggg ttatggttaa tcatctcccc
     7921 gacaatatcg ataaaggcct gtgcatccac cgcctgtgtg gtgatactgg ccccctgtaa
     7981 cgacgcccgg atgattttca ccaggttttc catttccaga atatcagccc ggcttttttt
     8041 cttcgaggga gaacagtacg agaagaatac ccggtaatgg cgcagggtca ggggcagatt
     8101 catcccctcc ggcagcggaa actgtgtcgc tgccgcgttc atataatagg cacgggtaat
     8161 ggcgttaaac cgttcagcct gttcacccga ccaggagaac tcacgcagcc cgtattcaat
     8221 cctgtcacca accagctgac tggacatcag atggatgcag aacggcaccc cgcgcggcag
     8281 tttggtgcgc agcatgtgat cgagggcctc cacaatggac tcattcgccc cattgatggg
     8341 aatggcttcc agcataaagc ccatcgtggt gtcattcatg aacagaccgg attcctggtt
     8401 gtaatcacgg tacggcagca gacgactgaa ctgcgggaag ctcatttcgc ccagaacttc
     8461 attggccttt gcggattcgt caggcagttt cagtgctgtg acgagggagt taaccgcctg
     8521 agtgacggcc tcaagtggat tattcacatg aattccttag ttgaaaaata aagcgagaaa
     8581 tgcggtagcc atgaagggaa tacctgtaat taacgcgcca tttcccggca catatacaaa
     8641 gatttctgtt ttctgaatat ccactcatgt tcatccggaa ttaaatcact atgttctgcg
     8701 actgacttat gcataatgtt ttctctgtct ttcctgatac gcctgacatt caacgcacaa
     8761 cgtcacaccg ggaaatattt tccgccgggc ttccggagca ggattcccgc atgcttcaca
     8821 gagataaaca ggaataccat gagcatttat tttctggcgt atccggttta ttcctgtcat
     8881 ggtcagttgt tctgtcactg aatatgcttc atcggcttca tcactcacgg aatattcctc
     8941 ccgacatgtt ctgacacgct accgcccatc ccttttcacg cacagggcac tcgttttaca
     9001 ggcagatttt gaatacagaa agcctgccgg cattgccggc tgatatacaa cttcagggcc
     9061 agttaattaa tacgtggttt tccccacgca gacggtttaa taacaaaaaa cacgctggat
     9121 ggctgatgat aaacatcctg attatcaata taaggcgcta tccataatgc agccgtctgc
     9181 tcacccgttc ttagcggacg aggaggtgtt accggcgcaa ctgaactgac cggaacaatc
     9241 gttttcactt cccgggcagc ggtaaacagc gggcgtggtg ccagcagttt ctgctccgga
     9301 tgtgctgtca ccgcaggtct gctgccggac ggagtggccg cggtgacggt ctgcaccggc
     9361 attgtccgga agttcccttc acccaggcgc ggcagtgatg ccgcaaccgg ctttgcttct
     9421 gaggactgct ccagtttttt ggccttctca ttggcctgct ccatcgtcat acaggtatcg
     9481 gatgtggtgg cgttacactc aaattccgta ttagttccgg cacagccgga aagtaataag
     9541 gtccccagca gaggaataaa taaagaaatc tgtttcattg tccctcacct ttctcatcgc
     9601 agttcacaaa atcattcttc aaatccctga ccgtacaggt ttttacaatg tcaggatttt
     9661 caaaaaccgt attccgtgat gatttataaa catatgccac aatgcgtttc ccccccgcat
     9721 caggttctgg cacactgact tcacataacg gaggggttat tccggattca tacagcaccg
     9781 gatactttat ttttttgacg ctgccatcag aaaccagctt attcatcgaa gggttcctta
     9841 tatttctgaa taattctgtc gattagttct ttcaccggaa cagattttcc gctaccggat
     9901 tgtccggcaa ccacaatatg ccccggagaa gaaaataagc tcatcgacat acccttcttc
     9961 atcacaccga cagcagccat attaaaattg tgcggcaatg attcagaact gaattccttc
    10021 ggtgcaggaa gtacgattct tgtggtgcag ttactgagaa cagcatgcat aagatcatct
    10081 gatacgcttt tatccggtac agagcgggca gtaataacat taatattacg catgttcatt
    10141 tttatctccg ttgtttctga ttgttctgtc atcagggaaa taaacatggc actccctgat
    10201 ttttcccggc agggaagtgt cttctgcaag aacttccttc agacgctcat ctgctgttgc
    10261 cacacggaca catttcattt ttccgggtcg caccggatat ttcccggtgc ctgccgcaaa
    10321 cgacatatac ataagtgcca gcgttgccca gaatgcggtg accagttgca tcagtgaccg
    10381 gtcagtctcc ctgacataat ctgcagcatc agcagcacgg taacggcaga ttttctcttc
    10441 tgctcctgga agatcatgca gagaaggcaa acattctctt acaggaaact gcccggcagg
    10501 ggctgtttgt cttacgaagt caatttcctg aaccagtaat tttcctggtg tggtgttgtc
    10561 cttccataaa acaaacagag ccatcagggc cattgtggcc agtggccaga taaccacaaa
    10621 cctgacgacc cacagcagcc agcgaacgac aaacgccaca cggaatgtca gtgcatcacc
    10681 cgccatttcc gccctccttg ccggcatccc cgcccagcgg gttcttgtct ccggacataa
    10741 actgctgcgg attcagattg cccagctgtt tcagcatctg gtcggtgtta aaaccgttca
    10801 ggtggctttc tgccgaggga ggattcggca ccgggctttc cgggttaccc tcttccgctg
    10861 tactctgtga ctgctccagc gccatttcct ccacggtttt cagctggaag ccgtcctgga
    10921 acaccacggt cacttcgttg cccgcaccaa tcggtatcac cgggtgatac tgttcggcac
    10981 gtttgatgta gtagtcactg agcgtctgtg cggctttcga tgcgccgcca ccgataccca
    11041 ttttcaggac atcaccagcc ccgtaagcgg ctgtggcacc cagcccgaca gccggctggg
    11101 aggcgcgctc cattccctga ccgataccgt caacaaatcc cgcgccccat gcccagccga
    11161 ggattttgcc gttacgcatc accacttcgc ccttgatacc gtttttaccc cggaagctga
    11221 catgcccctt aatcggcata tcaatggttt tgccgtcctt caggcagctg atattgcggg
    11281 tacgtacaat ggcacgctca ctggagacat ccccccaggc ttccagcccc acaaaacatc
    11341 ccgttgcgtc atacgttttg ctgttcggca tttccaccag gccggtgata cgcagctgca
    11401 tcggcaccgt ggattcatta ccggtgactg aggcattggc atccgcccct tcaatcagca
    11461 tggctttcgc aaaacttcct gacggaatgt acggcagtga tggtccctgt tttccctcat
    11521 tacgggtaaa caccttacgc tgtatccggt taggcaccgg cacagactgg tacgtcacct
    11581 gtggtggtgg cgtgacacca ttcccgggat aaaacgccgt cggcggtgga acagcaacgc
    11641 tgccctgcgg cgggaaggat acgggggtgt ttcctggctg tggttcgcct tccggcccgg
    11701 gcggtgaggc tggcgtctgc ggtacaggct caccggtcgc ggtgacggga tttgcaccca
    11761 gggctttcac ctgctctgcc agtgcagcat tgtcctgtcc cagcttttca atacgacgct
    11821 ggtcataacc gcgctgtttg ttcaggacat ccagttcacg acggatttcc tcatactgct
    11881 tctgcatctg tgccgccgtc acctgcatct ctgtagtagc atgctgacgc accttgtcat
    11941 caaaggtcgt atccaccaca ccggtcatat ccggcacagg ctcctgttca gccacggttt
    12001 caccgttacc ggacatgtcc acatcagaca gatacagcgc accaccaatc gcggaggctg
    12061 caccgacaac cacaatcccc agccacaggt actgcttgcg tttcacaatg gtattgatac
    12121 tggccatcag ttgccctccc cgtcacggat gacatacaca tccatgcgcg cacctgccag
    12181 taactggctg gcaggctggc tgaacatcac ggcacgggtt cccggctgcc agaagtcact
    12241 ttcccggata ctcagagcag acagagtttt attttccacg gcaaagcgga ccatcttcag
    12301 gtgattcccc gtccatacgg catctgccac tgaagacaga cccgccgggg cctgcagggt
    12361 ttcctttgtc accgggacct gataccagcc tgcgggtaat tttccgccac ggacggcctg
    12421 gctgatggtc acaagcaggg attcgtaagg cgtggacgtt tcccacgcac cggcttcttc
    12481 tccggttccg cgcaggtcac tgacaagctg aatggtacgc cccgcgcctt cacggggaac
    12541 ggcctgaatg gaaagattca gaccacgttc tgtttccaga atgaacgtaa agggcttttt
    12601 gttgacggtg gccaccacca cactgccgga ggcggtctgc tcattattgg tcagggcacc
    12661 atccagactg ttcacggcga taatccggtc accgggaacg gtaaacagat tcgggctggt
    12721 attgctgatg gcaatactgg cctgaccacc gttcaccatt ggcaccacgg tgggggccag
    12781 cgtaccgttt gcggccatca cgctgcagga aaaaaacagg ctgccgaata ttattgccgt
    12841 attatttttt ctcatcgtct gtttccccga aattatccag ccaggtcacc ccgttttccc
    12901 gcttcagaat aaggatgtaa tgtttgatat cagtgaaagg ttttgaatca ccaatccagg
    12961 ttttaagcac accacgaatt tccacacggc catactgagg ccagacacga acactggtct
    13021 ggaaaaaggc tgagttcacg ttatcgtttt taatacgctt cgcttcttca gccagaataa
    13081 ctttcatctg gttctgtgcg cccgggcgga tatattgcag aagcgcctga tgtgaggcat
    13141 cgacggtttc tgatgaaaca ttcagacgga gggcaataaa tgacagcgcc atctgctgta
    13201 aataagaggc gtcggcactg ttctgtgaca cggcaaaggg ggcattaaat gccattggcg
    13261 tcacggcagt gcgttgctca ttctgaagac ggtagttatt cactccctga atgacgttaa
    13321 cagagaggct gagaacaata agcactgaca taaatataaa ggcgatggcc attacacgac
    13381 tggtacttaa acgggcaccg tgttccatat aacaatcctg gtatcagttc tatttaatcc
    13441 actgccggaa acacgaatcg ggaacattat gaaaaatacc gcgcaacagg gctgttggca
    13501 tataccagta aatcaggtca cgtaaccagg aactgccccg cccttttttc agttttttaa
    13561 tcccgaaata aaccagaacc gctgcaccaa taccgaacag atatttcgat gttgtgatac
    13621 cccagccaat acagattgct gcggggatca gttcatccag tggcaggcca aaccagcggc
    13681 tctggttggt cagtgtttcc gggaaacgat atttcttaag tttattctcg tctcccgaca
    13741 tcgttttatt tcaggccaac gacggccata cccacagcaa taaatacaga gatgatggca
    13801 aaaccggcca ggaacttgac gtttttggtc atcatgtaca tgacagcacc gaccagaact
    13861 tcagccagaa caacccattt aacaacactg gagtccttac cgaaggtcgc cttaaccgtg
    13921 gagttaccac ttgccatcag gtcctgacta ccggaagcca tcgccagttg cgggaagaac
    13981 atcatcagaa cagcagccgg gagcacagcg cgtaccaggc gaagcatatt cagacgagtg
    14041 aatttagaaa aaaacgactt ctttttgacg ggcgcagaag caccctgaac acttaaaaca
    14101 gcattcataa gttacctcaa tttcggataa atgaataaaa ctagagtgta ttaaatgtta
    14161 tatcttcctc tttatctgcc tccctgaata tctccgagtt ataaaaatca ggaaacttga
    14221 tcaaatgatc aataactctg tctgcagcct catctgtttt acaccatcca ctacgatttt
    14281 tggctgcaat aagtagctgg ttagtttcat catccagacg cattgtcaga tacttaacca
    14341 gcgacttacc atagatattc cctgccctgt taaactttgg atagcggtga agatgatctt
    14401 taagtcttat tactgcctca aacgatcgac ttcttccgct tctgttactt gcctcaatta
    14461 atagactttc cacatctaaa ggtaatttta gttttaccat cttacctgtt gcagaacgtg
    14521 taccaaatct tttcaataac acctcccgct gtttatcttc tggttaccac ttatgtttgc
    14581 agaataatca gaaaaggtaa atagacggaa agtctatatt ttattaacac tttattaacg
    14641 cgtatttatg atacacatag ccttctcgta caaataatga ataaactttt tattgtagag
    14701 taagatgatt aactcatctt tattaggaac agagaagtag tcgcatatca gagacgcgtg
    14761 tttctttgat gtggagatgg atatgtttaa tattcttgct atagcattat gactgattcc
    14821 ggtgctatat aagtaaaaga catcatttac atatgatgat acagaagaat catcactcat
    14881 tcttctgatt atatttctga tatcatcact gacaatcgtt ttttgattat aactgtcttt
    14941 atgacgaaca tgagcagcat cataaaattg ccacagaata atatttctgt gtccattaag
    15001 aaatgactgg acagaaattg tccagaatct gttctgaata aaaacatcct ctacaagatt
    15061 aagatgcgta tgctcattcc tatatgcttc catctctgtg acagagatca attcacaaaa
    15121 atctctctgc gacagaagcc atttttcagc actttgatct tgtgtaagaa atgactcatg
    15181 aaacagcgta ttgcaaaaaa taaattttcc agtttcgtcc ctgatacagg ctggatttgg
    15241 ataatcctga ataactgccg tcagattttc cagcagatct atttgacgag catgtttttg
    15301 ttgaatacga tccatcggat acataggaac ctcctcacaa aggattctat ggacagtcga
    15361 tgcagggagt tcacgtctcc ctgcatcggc gattttcaat ttcaaatttt aacgtggcat
    15421 taaccacgta attaatatac taattatctt tcgtactgtc acctttttaa atcataaaa
//
LOCUS       DAPGUL010000105        15390 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.107, whole genome shotgun sequence.
ACCESSION   DAPGUL010000105 DAPGUL010000000
VERSION     DAPGUL010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15390
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.107"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            80..592
                     /gene="bmaE"
                     /locus_tag="RHX21_003542"
                     /gene_synonym="afaE-8"
     CDS             80..592
                     /gene="bmaE"
                     /locus_tag="RHX21_003542"
                     /gene_synonym="afaE-8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M agglutinin-type afimbrial adhesin BmaE/AfaE-8"
                     /protein_id="HDV1988680.1"
                     /translation="MNLKKIAIASSVFAGITMALTCHAVTVTATHTVESDAEFTIDWV
                     DAGPTTTDAKDGEVWGHLDMTQTRGTPTFGKLRNPQGETSPGPLKAPFSFTGPDGHTA
                     RAYLDSYGAPIHNYAGDNLANGVKVGSGSGNTPFVVGTASRLTARIFGDQTLVPGVYR
                     TTFELTTWTD"
     gene            complement(927..1787)
                     /locus_tag="RHX21_003543"
     CDS             complement(927..1787)
                     /locus_tag="RHX21_003543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000205482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDV1988681.1"
                     /translation="MTTATSLNELQKQIRDRYDSLSKRLQQVSRYVLDNTNSVAFDTV
                     AVIAERADVPPSTLIRFANAFDFTGFNEMKQLFRMHLVEETASYSDRARLFREMESEA
                     VPETPLDILQEFASSNSQALQQLAARAEPEMLEHAVQLLAYADTIYIAGLRRSFSIAA
                     YLTYALSHLECRPILLDGMGGMLREQISRIKACDIVVSISFSPYAEETVMVSKTAASV
                     GARQIVITDSQISPLATFSDLCFVVKEAQVDAFRSQSATLCLVQSLVVALAYRLGDKK
                     HNNTQENSNQ"
     gene            2078..3583
                     /locus_tag="RHX21_003544"
     CDS             2078..3583
                     /locus_tag="RHX21_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006687257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-acylating methylmalonate-semialdehyde
                     dehydrogenase"
                     /protein_id="HDV1988682.1"
                     /translation="METVANFIHGECVTGSGQRIQAIFNPATGEQIRQVVMSTAQETE
                     QAIAAAQLAFPAWARFAPLKRARVMFRFKALLEENMERLARIISEEHGKVFSDAVGEL
                     TRGLEVVEFACGIPHLQKGEHSANVGTGVDSHSLMQPLGVCAGITPFNFPAMVPMWMF
                     PIALATGNTFVLKPSEKDPSLALALAKLLKEAGLPDGVFNVVQGDKESVDVLLTDPRV
                     QAVSFVGSTPIAEYMYLTASAHGKRCQALGGAKNHCILMPDADMDMATNAIMGAAYGA
                     AGERCMALSVVVAVGDKTADELCARLEKKIASLRVGPGLNQTPENEMGPLISAAHRSK
                     VLGYIDSGEAQGANLRVDGRGLRVKGHEQGYFVGPTLFDNVTPEMTIYKEEIFGPVLS
                     VVRVADYASAVDLINRHEYGNGSAIFTRDGGCARRFCEEVQAGMVGVNVPIPVPMAFH
                     CFGGWKRSIFGALNVHGNDGVRFYTRMKTITARWPEMQQETGAAFSMPTLG"
     gene            3595..5520
                     /gene="iolD"
                     /locus_tag="RHX21_003545"
     CDS             3595..5520
                     /gene="iolD"
                     /locus_tag="RHX21_003545"
                     /EC_number="3.7.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001192846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3D-(3,5/4)-trihydroxycyclohexane-1,2-dione
                     acylhydrolase (decyclizing)"
                     /protein_id="HDV1988683.1"
                     /translation="MQTERMTMAQALVRFLNQQYVSVDGKETPFVEGVATIFGHGNVL
                     GIGQALEQDPGHLQVMQGCNEQGIAHMATGFAKQHRRQRIFAVTSSVGPGAANMVTAA
                     ATATANRIPLLLLPGDIYACRQPDPVLQQIEQYHDLSISTNDCFRPVSRYWDRINRPE
                     QLMSAMLSAMRTLTDPANTGAVTICLPQDVQGEAWDYPLSFFARRVHHIERRPPDPQR
                     LAQAHALISRKRRPLVVCGGGVRYSGAHEALREFVEVLQLPFAETQAGKGALVSDHPL
                     NLGGVGVTGGMAANQLAPQADLVIGIGTRLTDFTTGSKALFSHPDVEFLLLNVAEFDS
                     LKLDATALIADARTGLTALTHALKDYRSGWGEAIAHAKSAWHDECCRLWERQWHPDDV
                     PEVAGHLDAQLMEYGETLNTHLTQTRVLGLINQHIEDNAIVVGAAGSLPGDLQRLWQV
                     KTPDSYHLEYGYSCMGYEVAAAIGAKLAKPQQPVYAMVGDGSYMMLHSELQTAVQEGI
                     KVTILLFDNASFGCINNLQMGHGMGSFGTENRYRNPKTGQLDGPLVKVDFAQNAESYG
                     CRAWRVHNEKSLLAALEASRAHPGPTLLDIKVLPKTMTHDYASWWRTGNAQVAESPAV
                     RQAAEQTQAQVKKARQY"
     gene            5805..6791
                     /gene="iolG"
                     /locus_tag="RHX21_003546"
     CDS             5805..6791
                     /gene="iolG"
                     /locus_tag="RHX21_003546"
                     /EC_number="1.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013098257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol 2-dehydrogenase"
                     /protein_id="HDV1988684.1"
                     /translation="MFNIALLGAGRIGQVHAANIASHSATTLWSVVDPNQEFATRLAT
                     QYQARQQSLDEAMTDPNVHAVLIASATDTHADLIEMAARYGKAIFCEKPVHLDLARVR
                     DCLKVVKEYDVPLFIGFNRRFDPQFRRVKTDTQAGRIGKPESLLIISRDPSPPPAEYV
                     RVSGGMFRDMTIHDFDMARFIMGEEPVSVYAQGSNLVDPAIGGAGDIDTAFIVLKYAS
                     GAMATIVNSRRSSYGYDQRLELHGSEGLLCAGNILENQVQHYGKQGCTSALPEHFFLQ
                     RYKSAYAAEWEHFVAVLRGEAVPDCSGDDGERALYLADKALESLRCQREIVL"
     gene            6823..7752
                     /locus_tag="RHX21_003547"
     CDS             6823..7752
                     /locus_tag="RHX21_003547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015871439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDV1988685.1"
                     /translation="MKKLILAALIAMTSGAAIAENEQIVFSTPNLAMPFEVHMQRTAV
                     KAAKEMGVKLQVLDGQGSSPKQVADLENAITRGAQGFIVSPNDVNAVSSAVDEIQDTK
                     LPVVTLDRSVDSQKKVPHFGANNYKGGQAIGDFVKTKFPNGAEIILLTGQPGSSSNIE
                     RTKGIRDSLKAGGDMYKIVADQTGNWMRSEGMRIVESVLPSLPKRPQVILSANDDMAL
                     GAIEALQSQGVKPGEILVTGFDAVPEALARVRDGWLAVTADQRPGFAVTTAMSQLVAN
                     VREKKTITGADYPPTLITKENLQQAERIAEAGN"
     gene            7804..9351
                     /locus_tag="RHX21_003548"
     CDS             7804..9351
                     /locus_tag="RHX21_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020883046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDV1988686.1"
                     /translation="MSQPLLKVTDLAKSFSGVWALSSAQLTVGTGEIHALLGENGAGK
                     STLLKALAGAQPQTRGEIWFNGETLPVDDSPVERQNKGIITIYQEFNLLPNMTVAENM
                     FLGREPRKRNLIVDEKAVNQEAQVILDYLQLNVAPTTPVARLSVAQQQMVEIARALTL
                     NARLIIMDEPSAALSDSEVESLHRVVRELKNRGVSIIYVTHRLHEVFQLCDRFTVFQD
                     GRFTGTGAVTETNVEQLIRLMVGRDVAFNRRPASETHHEDKPVRLSVKGLSREKPPLD
                     PHGIALHDISFHVHAGEVLGIAGLVGAGRTEVARCLFGADAFTTGSFELDGVPYQPRD
                     PLYALEQGLALVPEDRKKEGAVLGLSIRDNLSLSCLSSLLQWRWFVNTRKEDDLIESY
                     RQALQIKMVNSTQEVRKLSGGNQQKVILARCMALNPRVLIVDEPTRGIDVGTKSEVHQ
                     VLFDMAKKGVAVIVISSDLPEVMAVSDRIITLSEGRLTGEIHGDDANEERLMTMMAIN
                     HNALNAA"
     gene            9363..10391
                     /locus_tag="RHX21_003549"
     CDS             9363..10391
                     /locus_tag="RHX21_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003826102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDV1988687.1"
                     /translation="MTQMIPKTQVPVKRAGRIDPIAFFERFGVLIFMILLLIFFQSQN
                     SNFFSERNIFNILTEVSIYGIMAVGMTFVILTAGIDLSVGSILAVCAMTAAYVIKGDN
                     FTTVDPNAWGGMSWLIGLGICLTMGTAIGFLHGLGVTRLRLPPFIVTLGGMTIWRGLT
                     LVINDGAPIAGFDQGYRWWGRGELLGISIPIWIFAIVAIGGYLALHKTRWGRFVYAIG
                     GNPEAARLAGVNVKRVLVSVYVLIGCLAGLAGFILSARLGSAEAVAGISFELRVIASV
                     VIGGTSLMGGYGRIGGTIIGSIIMGILINGLVLMNVSAYYQQIITGLIIVLAVAFDTY
                     AKSRRGAL"
     gene            10400..11533
                     /locus_tag="RHX21_003550"
     CDS             10400..11533
                     /locus_tag="RHX21_003550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013098253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDV1988688.1"
                     /translation="MKEVRIGLIGTGYIGKAHAIAYAQAPTVFNLRGKLVREMVAEVN
                     PALAAERAQAFGFNRSTGDWRVLVADPAIDVVDICSPNHLHKEMALEAIRHGKHVYSE
                     KPLALNAHDAREMVDAAKRAGVKTLVGFNYMKNPTAQLAKEIIARGEIGEVIHFYGTH
                     NEDYMADPLSPIHWHCFKETAGLGALGDLAAHIVNMAQYLVGEIEQVCGDLKIVVPAR
                     PAKAGSSEMVTVENEDQAHAMVRFAGGAQGVIETSRVACGRKMGLSYVITGTKGAISF
                     TQERMAEIKLYLHDDPVNRQGFQTLLVGPAHPDYGAFCMGAGHGIGFNDQKTVEVRDL
                     VDGIATDAPMWPDFEEGWKVSRVLDAIALSHQQGLWLNVNDIV"
     gene            11546..13450
                     /gene="iolC"
                     /locus_tag="RHX21_003551"
     CDS             11546..13450
                     /gene="iolC"
                     /locus_tag="RHX21_003551"
                     /EC_number="2.7.1.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008502114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-2-deoxygluconokinase"
                     /protein_id="HDV1988689.1"
                     /translation="MEKQFDVICMGRVAVDLYSQQIGARLEDVSSFAKYLGGSSGNVA
                     YGTARQGLRSSMLARVGDEHMGRFLREELNQVGCDTSHLITDKERLTALVLLGIKDRD
                     TFPLIFYRDNCADMAITASDVDESYIASARCIAITGTHLSHPQTREAVLTALNYARRH
                     GVRTVLDIDYRPVLWGLTSLGDGETRFIVAEQVTRELQEVLHLFDVVVGTEEEFHIAG
                     GSTDTLQALAQVRHVSKATLVCKRGALGCSVYTDAIPPRLDDGLTVTGVRVEVLNVLG
                     AGDAFMSGLLRGYLNDEGWEQACRYANACGALVVSRHGCAPAMPSKIELDDYLSRAAL
                     VPRPDIDPRLNHLHRVTTRRREWPELCVMAFDHRSQLEDMALQCGASLKRIPALKQLI
                     LQASREAASSAGLEGKAGLLCDGTFGQDALNAITGEGWWIGRPIELPGSRPLEMEHGN
                     IGTQLISWPQEHVVKCLVFFHPEDAHGLRLEQEQKIAEVYHACCQSGHELLLEVILPA
                     TMPRSDELYLRAISRFYNLGIYPDWWKLPPLSAEGWTALSEIIARRDPHCRGVVILGL
                     DAPAEQLRADFKAAAGQALVKGFAVGRTLFGDASRAWLKHDIDDAQLVARIRDNYLQL
                     IAWWRERGHA"
     gene            13462..14352
                     /gene="iolE"
                     /locus_tag="RHX21_003552"
     CDS             13462..14352
                     /gene="iolE"
                     /locus_tag="RHX21_003552"
                     /EC_number="4.2.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010433880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inosose-2 dehydratase"
                     /protein_id="HDV1988690.1"
                     /translation="MSVQLGINPLTWTNDDLPSLGAETSLETCLSEGKEAGFAGFELG
                     NKFPREARLLGPILQRHDLQLVSGWYSGRLLERSVEDEIAAVQSHLTLLRELGAKVLV
                     FAEVSGCIHGEQQTPVHLRPRFPQECWKEYGEKLTVFARYTQQQGVQIAYHHHMGTVI
                     ESAQDVDNLMLHTGEEVGLLLDTGHLTFAGADPLAVAQRWASRINHVHCKDVRADVLA
                     DVKNRKTSFLDAVLSGVFTVPGDGCVDYPPIMQLLKTQDYHGWLVVEAEQDPAIAHPL
                     TYARLGYNNLSRLARDAGLI"
     gene            14362..15183
                     /gene="iolB"
                     /locus_tag="RHX21_003553"
     CDS             14362..15183
                     /gene="iolB"
                     /locus_tag="RHX21_003553"
                     /EC_number="5.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
                     /protein_id="HDV1988691.1"
                     /translation="MSRLLSRWQQPNAEGRTQSVTPESAGWGYVGFEAYELEEGQQLT
                     LPAVSEERCLVLVAGRAFISTPSAQFTDIGERMSPFERIKPWAVYVTPQEAVQVKALT
                     KLELAVCTAPGKGTYPTRLIAPQDIDGEARGNGHNQRYVHNILPEDKPADSLLVVEVW
                     TNEGCTSSYPSHKHDTNNPPQESYLEETYYHRLNPEQGFCMQRVYTDDRTLDECMAVY
                     NRDVVMVPKGYHPVATMAGYDSYYLNVMAGPVRKWIFTWEKEHSWINTEYSAISL"
BASE COUNT         3398 a         4050 c         4562 g         3380 t
ORIGIN      
        1 gggccagtgt ttattgtggt gaagcagtat tatagaaata tgttttgcca tttattataa
       61 ccaagtataa ggataaggta tgaatttaaa gaaaatagct atcgcaagca gtgtctttgc
      121 aggtataaca atggcgctaa cttgccatgc tgtgacagta acagccactc atacagttga
      181 atcagatgct gaattcacaa tagattgggt cgacgctggg ccaacgacta cagatgcaaa
      241 agatggtgag gtttgggggc accttgatat gactcaaacc aggggaacac caacattcgg
      301 aaaactccgc aatcctcaag gagagacttc gccaggaccg ttgaaggcgc cattcagttt
      361 taccgggcca gatggtcata ctgcaagagc gtaccttgat tcatacggcg caccgattca
      421 caactacgca ggggataacc ttgctaatgg ggtgaaggta ggtagtggaa gcggaaacac
      481 tccatttgtt gttgggacag caagtcgact aactgcaaga atcttcggag accagacatt
      541 ggttccagga gtctaccgga caacctttga attaactact tggaccgact gacggaaaat
      601 taacctgatg aaagaagggg gctatatgtc ccccttgttg atttaccaac ataaaatggt
      661 tgtgtttaaa tcagcttggc agtgaaaagt agtcatgaga ttataaatgt tgctgcccaa
      721 aagtttaaag aagccgttat ctttgggtta cattactacc tacaagagaa atcttcctcg
      781 ctaataaggc cctcgctgta cgctaacatg aggcatgacc ttttagggag atagcagtac
      841 agttgatatt caagctgaag tctgtatcgc tactggcacc gaatcattta ctcttatatg
      901 gactcggggg aggagttcat tggtcattat tggttactgt tttcctgggt attattatgt
      961 tttttatctc ctaaacggta agctagcgcg accactaacg actgcaccag acacaatgtt
     1021 gccgactgag accgaaatgc gtccacctga gcctctttca ccacaaagca gagatcactg
     1081 aacgttgcca gtgggctgat ctggctatcc gtaatcacaa tctgccgagc gccgacgctg
     1141 gcggcggttt tgctgaccat caccgtttct tccgcgtacg gcgagaaact gatcgacacc
     1201 acaatgtcgc acgccttaat acggctgatc tgttcgcgca gcatgccgcc catcccgtca
     1261 agcagaatag ggcggcactc taggtggctt aaagcatagg tgagataagc agcaatgcta
     1321 aaggatctgc gtaatccggc gatgtaaatg gtgtcggcgt aggccagtag ttgtacggcg
     1381 tgctccagca tctccggttc ggcgcgggca gccaactgct gcagcgcctg cgagttcgaa
     1441 ctggcgaact cctgcaaaat atcgagcggc gtttcaggta cggcttcgct ctccatttcg
     1501 cggaacagtc gcgcacgatc gctgtagctg gcggtttcct ccaccaggtg catacgaaat
     1561 aactgtttca tttcgttgaa gccggtgaag tcaaaggcat tggcaaaacg aatcagtgta
     1621 gagggtggaa catcggcacg ttcggctatg accgcaaccg tatcaaacgc gacactgttc
     1681 gtattatcca gtacatagcg ggagacctgc tgcagccttt tgctcaggct atcgtagcga
     1741 tcgcggattt gcttttgtag ttcgttcagg ctggttgctg tcgtcatgtt atccccctat
     1801 ccagtctcat gattctaaac gcaaaaccgc gtcttttaaa tgttggccat ccacttggca
     1861 gcaaaaatga aacagaagct tcagtcattt cctcgcccga aactcctaat agctcaggct
     1921 gagtcagtga tgctggctgt tcacataaaa atccatcctt gatcacaata atcattattt
     1981 attttatttc aacttaaaat ggaatatttg tttcatatat agtgttcagt acataacgtt
     2041 caggtaacaa tcacgtatca acagcgagag gttaaggatg gagacggtag cgaattttat
     2101 tcacggcgaa tgtgtcaccg gttcaggcca gcgcattcag gcgatcttca acccggccac
     2161 tggcgagcag attcgccagg tggtgatgag tacggcacag gaaaccgaac aggcgattgc
     2221 cgcagcacag ttggcgtttc ccgcgtgggc acgttttgct ccactcaagc gcgcgcgtgt
     2281 gatgttccgc ttcaaagcgt tgcttgaaga gaatatggag cgtctggccc gtattatcag
     2341 tgaagaacac ggtaaggtct tctcagatgc agtaggtgaa ctgacccgtg gtctggaagt
     2401 ggtagaattc gcctgcggca tcccacatct gcaaaaaggc gaacactctg cgaacgttgg
     2461 cacaggtgtc gacagccact cactgatgca gccgctcggg gtctgcgccg ggatcacgcc
     2521 gtttaacttc ccggcgatgg tgccaatgtg gatgttcccg atagctctgg cgacaggcaa
     2581 caccttcgtg ctgaaaccgt cggaaaaaga tccgtctctg gcgctcgcgc tggcgaaact
     2641 gctgaaagag gcaggcctgc cggacggcgt attcaacgtg gtgcagggcg ataaagaatc
     2701 cgttgatgtg ctcctgaccg acccgcgcgt gcaggccgtc agttttgtcg gttcaacacc
     2761 gattgccgaa tacatgtacc tgactgcgtc cgcccacggt aagcgctgtc aggcgctcgg
     2821 cggtgcgaaa aaccactgca ttttaatgcc ggatgccgat atggatatgg cgacaaacgc
     2881 cataatgggc gcagcttatg gtgcggcagg agaacgctgc atggcgcttt ccgtggtggt
     2941 ggcggttggc gataaaacgg ctgatgaact ctgcgcccgg ctggaaaaaa agatcgcttc
     3001 gctgcgcgtc ggacctggcc tgaaccagac gccagaaaac gagatggggc cgctgatctc
     3061 cgccgcacac cgcagcaaag tgttgggcta tatcgacagt ggcgaagctc agggggctaa
     3121 cctgcgtgtg gacgggcgtg gcctcagagt gaaagggcac gagcagggct atttcgttgg
     3181 gccgactctg ttcgataacg tcaccccgga gatgaccatc tataaagaag aaattttcgg
     3241 accggtgctt tctgtggtgc gcgtagcaga ttacgccagc gcggtggatc tgattaaccg
     3301 acacgaatat ggtaatggct cggccatttt cacccgtgac ggtggctgcg cacgccgctt
     3361 ttgtgaagag gtgcaggcgg gtatggtggg ggtcaacgtg ccgatcccgg tgccaatggc
     3421 attccactgt ttcggtggct ggaaacgttc catttttggc gcgctcaatg ttcacgggaa
     3481 cgatggcgtg cgtttctaca cccgaatgaa aaccatcact gcacgctggc cggaaatgca
     3541 gcaggagaca ggtgcagcgt tctccatgcc gacgctgggc tgacaggggg ttttatgcaa
     3601 accgaacgta tgactatggc ccaggcgctg gtcagatttc ttaaccaaca atatgttagc
     3661 gttgatggta aagaaacgcc ctttgtggag ggcgtggcaa cgatctttgg gcacggaaac
     3721 gtgctcggta tcggccaggc gctggagcag gatcctggtc atctgcaggt gatgcaaggc
     3781 tgtaacgagc aggggattgc ccatatggcg acgggattcg ccaaacagca tcgccgtcag
     3841 cgtatttttg ctgtcacctc atccgttggg cctggcgctg ccaatatggt gacggcggca
     3901 gcgacggcca cggcgaaccg cattccactg ctgctactgc caggggatat ctacgcctgc
     3961 cgccagcctg accccgtgtt gcagcagatc gagcagtatc acgatctcag catcagtacc
     4021 aacgattgct tccgcccggt ttcccgctac tgggaccgca tcaaccgtcc tgaacagctt
     4081 atgagcgcga tgttaagtgc gatgcgaacg cttactgacc ccgcaaatac aggagcggtg
     4141 accatttgcc tacctcagga tgtgcagggg gaggcctggg attaccccct gagtttcttt
     4201 gcgcgtcggg tgcatcatat tgaacgccgt ccgcctgacc cgcagcgact ggcgcaggct
     4261 catgcattga tttcccgcaa gcgccgtcca ctggtggtgt gcggcggtgg cgtgcgttac
     4321 tccggtgcgc atgaggcgtt acgggaattt gttgaagtgc tgcaattgcc gtttgccgaa
     4381 acccaggccg gtaagggggc gctggtaagt gaccacccgc ttaatctggg cggggtgggc
     4441 gtgacgggcg gaatggctgc caaccagctt gcgccgcagg ctgacttagt gattggcatc
     4501 ggcacgcgcc tgacggattt tactaccggc tctaaggcgc tcttttctca tcccgacgtc
     4561 gagttcctgc tgctgaacgt ggctgagttt gactccctga agctggatgc caccgcgctc
     4621 attgccgatg cccgaactgg tctgacagcg ttgacccacg cactgaaaga ttatcgtagt
     4681 ggctgggggg aggcgattgc ccatgcgaaa tccgcttggc acgatgaatg ctgtcgactg
     4741 tgggaacgcc agtggcatcc tgacgacgtt cccgaagtgg cagggcacct tgatgcacag
     4801 ctaatggaat acggtgaaac gctcaacaca cacctgaccc agacgcgggt gttggggctc
     4861 attaaccagc atattgagga taacgccatt gtggtggggg cggccggatc gctgccaggg
     4921 gatttgcaac gcctctggca ggttaaaacg cctgacagtt accatctgga gtatggttac
     4981 tcctgcatgg ggtatgaggt cgcagcggct attggtgcga agctggcaaa acctcagcag
     5041 ccggtgtatg ccatggtagg cgatggttcg tacatgatgc tgcactcaga gctgcaaact
     5101 gccgtacagg agggaattaa ggtcaccatt ctgctgtttg ataacgccag cttcggctgc
     5161 attaataacc tgcagatggg gcacggaatg gggagttttg gcacagaaaa tcgttaccgt
     5221 aatccgaaaa caggtcagct tgacgggccg ttggtgaagg tcgattttgc gcaaaacgcg
     5281 gaaagctacg gttgccgcgc atggcgggta cataatgaga aaagcctgct ggcggcgctg
     5341 gaagcctcgc gcgctcaccc gggaccgacg ctcctcgaca tcaaagtgct accaaaaacc
     5401 atgacccatg attacgcgtc atggtggcga accggcaacg cacaggtggc agagtcgcca
     5461 gcagtgcgcc aggccgccga gcaaacacag gctcaggtga aaaaagctcg tcagtattga
     5521 gttttcctgt cgtaacgaaa ttttcatttc atttttcttt tttcccctca cccatcccct
     5581 ctcccaacgg gagaggggat ggtacagttt ttattccctc ccccccttgt aatggaggga
     5641 catatcttcc tcggcgttgt gagattgata acaaaattta tctaatacat ctcaaaagtg
     5701 ttaactggca ctcaaaatat aattttcact atttataaaa atgaaataaa tgttttattt
     5761 gtagtgtcgt tagttcaccg cattcatcaa caccgggagc cgttatgttt aacattgctt
     5821 tactgggcgc tggccgaatt ggccaggtac atgcagctaa catcgccagc catagtgcga
     5881 ccacgctctg gtctgtggta gacccgaatc aggagttcgc cacgcgtctc gcgacacagt
     5941 atcaggcgcg ccagcagagc ctggatgagg cgatgaccga tccgaacgtt catgccgtat
     6001 tgatcgcctc cgcgaccgac acccacgcgg atctgattga aatggccgcc cgttacggca
     6061 aagccatttt ctgtgaaaaa ccggtacacc ttgatcttgc ccgcgtacgc gactgcctga
     6121 aagtggtcaa agagtatgac gtaccgctgt ttatcggttt taaccgccgc tttgacccac
     6181 agttccgtcg cgtgaaaacc gacactcagg ccgggcgtat cggcaaaccg gaatcactgc
     6241 tgatcatctc ccgcgatccg tctccaccgc ctgcggagta cgtgcgtgtt tccggcggca
     6301 tgttccgtga tatgaccatc cacgactttg acatggcacg cttcatcatg ggtgaagagc
     6361 cggtgtcggt gtatgcacag ggcagcaatc tggtggatcc ggcgattggc ggagcgggag
     6421 atatcgacac cgcatttatc gttctgaaat atgcctccgg cgcgatggcg accatcgtca
     6481 acagtcgccg ctcttcatac ggctacgacc agcgcctgga gctacacggt tccgaagggc
     6541 tgctgtgcgc gggcaatatc cttgaaaacc aggtgcagca ctacggcaaa cagggttgca
     6601 ccagcgcgct gccggaacac ttcttcctgc aacgctacaa atccgcttac gcagcggaat
     6661 gggagcactt tgttgcggtt ctgcgcggcg aagcggtgcc tgattgcagc ggcgatgatg
     6721 gtgaacgtgc gctgtaccta gcggataaag cgctggaatc actgcgttgc cagcgtgaga
     6781 tcgtcctcta aacacaacaa ccctacacag agagacataa taatgaaaaa actgatctta
     6841 gccgccctaa tcgccatgac atccggggcc gccatagccg aaaacgagca aattgttttc
     6901 agtacgccaa acctggccat gccgtttgaa gttcacatgc agcgcacggc ggtgaaagcc
     6961 gcaaaagaga tgggggtgaa acttcaggta ctggacggtc agggcagctc accgaagcag
     7021 gtggctgacc tggaaaacgc catcacccgt ggtgcgcagg gctttatcgt ctccccgaac
     7081 gatgtgaacg cggtctccag tgcggtagat gaaattcagg atacgaagct gccggtcgtt
     7141 acgcttgacc gctctgtcga cagccagaaa aaagtgccgc actttggtgc caacaactac
     7201 aagggcggcc aggcgattgg cgacttcgtc aaaaccaaat tccccaacgg cgcggagatc
     7261 attctgttga ccggtcaacc gggttcctcc tccaacattg aacgcaccaa agggatccgt
     7321 gacagcctga aggctggcgg ggatatgtac aagatcgtcg ccgatcagac cggcaactgg
     7381 atgcgctcgg aagggatgcg cattgtcgaa agcgttttgc cgtcgctgcc aaaacgtcct
     7441 caggtgatcc tctctgccaa cgatgatatg gcgctggggg cgattgaagc gctgcagagt
     7501 cagggtgtga aaccgggtga aatcctggtc accggttttg atgcggtacc ggaagcactg
     7561 gcccgcgtgc gcgacggctg gctggcggtt acggcggatc agcgtcccgg ctttgcggtg
     7621 accacggcga tgagccaact ggtggctaac gtgcgtgaga aaaaaactat caccggggcg
     7681 gactatccgc cgacgctgat caccaaagag aacctgcaac aggctgagcg tattgctgag
     7741 gccggtaact gatttgtctg gagccgccgt acgggcggct ccccataaat aaggagcagg
     7801 ctgatgtcgc aacccttact gaaagtaacc gacctggcaa aaagcttttc cggcgtatgg
     7861 gcgctgagca gcgcccagct caccgtcggc acgggtgaaa ttcacgcttt gctgggcgaa
     7921 aacggcgctg ggaaatccac gctgttgaag gcactcgcgg gcgcacagcc acaaacgcgc
     7981 ggggagatct ggttcaatgg cgaaacgctg ccggtggacg actccccggt agaacggcag
     8041 aacaagggca ttatcaccat ctatcaggaa ttcaacctgc tgcccaatat gaccgttgcg
     8101 gaaaacatgt ttctcggacg cgaaccgcgt aaacgtaacc tgatcgtcga cgaaaaagcg
     8161 gtcaatcagg aagcgcaggt gattctcgat tatctgcaac tgaatgtcgc acccaccacg
     8221 ccagtcgccc gtctgagcgt ggcccagcag cagatggtgg agattgcccg ggcgctgacc
     8281 ctcaatgcca ggctgatcat catggatgaa ccctccgccg ccctgagtga cagcgaggtg
     8341 gaaagcctgc accgcgtggt gcgggagctt aaaaaccgcg gcgtgagcat tatttacgtt
     8401 actcaccgtc tgcatgaagt tttccagctt tgcgatcgtt tcaccgtttt ccaggatggc
     8461 cgtttcaccg gcaccggcgc agtgacggag acgaacgtag agcagttgat ccgcctgatg
     8521 gtagggcgtg atgtggcctt taaccgccgc cctgccagcg aaacccacca tgaagacaaa
     8581 cctgtccgtt tgtcggtgaa ggggttaagc cgggaaaaac cgccgctgga tccacacggc
     8641 atcgccctgc atgacatcag ttttcacgtc catgctgggg aagttctggg tatcgctggg
     8701 ctggtggggg ctggtcgtac tgaggtagcg cgctgcctgt ttggcgccga cgcctttacc
     8761 accggcagct ttgaactgga cggcgtgccg taccagccgc gtgacccact ttatgcgctg
     8821 gagcaagggc tggcgctggt gccggaagat cgcaaaaaag agggggcggt gctgggtctg
     8881 tcgattcgcg acaacctgtc gctctcctgc ctctcctcgc tgttgcagtg gcgctggttt
     8941 gtgaataccc gcaaagagga cgacctgatt gagtcctacc gccaggcgct gcagatcaaa
     9001 atggtcaaca gcacgcaaga ggtgcgtaag ctctctggcg gcaaccagca gaaagttatc
     9061 ctcgcgcgct gcatggcgct caatccacgg gtgttgattg tcgatgagcc gacgcgtggc
     9121 atcgacgttg gaaccaaatc ggaagtgcac caggtgctgt ttgatatggc gaaaaagggc
     9181 gtggcggtga tcgtgatctc ctccgatctg cctgaagtga tggcggtgtc tgaccggatc
     9241 atcaccctta gtgaaggccg gttaactggc gagatccacg gtgacgacgc taacgaagaa
     9301 cggctgatga cgatgatggc tatcaaccac aacgccctga acgcggcata acggagtttc
     9361 tcatgacgca gatgattcct aaaacgcagg tcccggtaaa acgcgccgga cgcatcgatc
     9421 ccattgcctt cttcgagcgc ttcggggtac tgattttcat gatcctgctg ctgatcttct
     9481 ttcagtcgca gaacagtaat tttttctctg aacgcaatat tttcaacatc ctgaccgaag
     9541 tctccatcta cggaatcatg gccgtgggga tgaccttcgt cattctgacc gctgggatcg
     9601 acctctccgt gggctctatt ctggcagtgt gcgccatgac agcggcgtac gtgatcaaag
     9661 gcgacaattt caccacagtc gatccgaacg cttggggcgg tatgagctgg ctgattgggc
     9721 tggggatttg tctgaccatg ggtacagcga ttggcttcct gcacggtctg ggcgtcaccc
     9781 gcctgcgcct accaccgttc atcgtcaccc ttggcgggat gaccatctgg cgtggtctga
     9841 cgctcgtgat taacgacggt gcgccgattg ccggcttcga tcagggttat cgctggtggg
     9901 gacgagggga attgctcggc atctccattc cgatctggat cttcgccatc gttgccattg
     9961 gtggttatct ggcactgcat aaaacccgtt gggggcgctt cgtctatgca attggtggca
    10021 acccggaggc ggcacgtctg gctggggtaa acgtgaagcg tgtgctggtt agcgtctatg
    10081 tgctgattgg ctgtctggcg gggctggcgg gcttcatcct gagcgctcgt ctggggagcg
    10141 ctgaggcggt tgccgggatc tcctttgagc tgcgtgttat tgcctcggtg gttattggcg
    10201 gcacgtcgtt gatgggggga tatgggcgta tcggcggcac tatcatcggc tccatcatca
    10261 tgggcattct gattaatggc ctggtactga tgaacgtctc ggcctactac cagcaaatta
    10321 tcaccggatt aattatcgtt ctggcggtgg cattcgacac ctatgccaag agccgtcgcg
    10381 gcgcactgtg aggatcacga tgaaagaggt tcgtattgga ttgattggca ccgggtatat
    10441 tggcaaggcg catgccattg cctatgccca ggcaccgacg gtgttcaatc tgcgcggcaa
    10501 actggtgcgc gagatggtgg ctgaggtgaa tccggcgctg gcggcagaac gcgcgcaggc
    10561 gtttggcttc aatcgctcaa ccggagactg gcgggtgctc gtggccgacc cggccattga
    10621 tgtggtggat atttgctccc ctaaccatct tcacaaagag atggcgctgg aggcgatccg
    10681 ccacggcaag cacgtctatt cggaaaagcc gctggcactg aatgcccacg acgcgcgtga
    10741 gatggtcgac gctgcgaagc gggcaggggt gaaaacgctg gtgggtttca attacatgaa
    10801 aaacccgacg gcacagttgg cgaaagagat tattgcgcgc ggcgaaattg gtgaggtgat
    10861 ccacttctac ggaacccaca acgaagacta tatggccgac ccgctttccc ctattcactg
    10921 gcactgtttt aaagagaccg ccggactggg ggctctgggt gacctggcgg cacatatcgt
    10981 caatatggcc cagtatctgg tgggagagat tgagcaggtc tgtggcgatc tgaaaattgt
    11041 ggtgccggca cgtccggcaa aggccggatc gtcggaaatg gtcaccgtgg aaaatgaaga
    11101 tcaggcccac gcgatggtgc gctttgcggg cggggcgcag ggcgtcattg aaacttcccg
    11161 cgtcgcctgc ggccgcaaga tggggctgtc atacgtcatt actggtacca aaggagcgat
    11221 cagttttacc caagagcgga tggcagagat aaagctctat ctgcatgatg atccggtgaa
    11281 ccgtcagggg ttccagacac tgttggtcgg tccggcacac ccggattacg gcgcgttttg
    11341 catgggcgca ggtcatggta tcggctttaa cgatcaaaaa acggtggaag tgcgtgatct
    11401 ggtagacggc attgccaccg acgcaccgat gtggccggac ttcgaagagg gctggaaggt
    11461 ctcgcgcgtg ctggatgcca tcgcactctc acaccagcag ggcctctggc tgaacgtgaa
    11521 tgacattgtc tgaagagggt tcaacgtgga aaagcagttt gatgtgatat gcatgggccg
    11581 cgtggcggta gacctctaca gccagcaaat tggtgcccgc ctggaggatg tgtcgagctt
    11641 cgccaaatat ctcggcggct cgtccggcaa cgtggcgtac ggtaccgcgc gtcagggctt
    11701 acgctcgtca atgctggcgc gcgttggcga tgaacatatg gggcgcttcc tgcgggaaga
    11761 gttaaaccag gtgggctgcg ataccagcca tctgatcacc gataaagaac gcctcacggc
    11821 gctggtgcta ctcggcatta aagaccggga cacctttcct ctgatttttt atcgcgataa
    11881 ctgcgcggat atggcgatta ctgccagcga tgtggacgaa agctacattg cctccgcacg
    11941 gtgtattgcc atcaccggga ctcacctttc tcacccgcag acccgcgagg cggtgctgac
    12001 ggcgctgaat tacgcccgcc gtcacggcgt gcgcacggtg ctggacatcg actaccgtcc
    12061 ggtgctgtgg ggactaacct ctctaggaga cggcgaaacg cgttttatcg ttgccgaaca
    12121 ggttacccgt gaacttcagg aggtgctaca ccttttcgac gtcgttgtcg gcaccgaaga
    12181 ggagtttcac attgcggggg gcagcaccga tactttgcag gcgctggcgc aggtgcgcca
    12241 cgtcagcaag gcgacactgg tttgcaagcg cggcgcgctg ggctgttcgg tgtataccga
    12301 tgccattcca cctcggctgg atgacggcct gacggtgacc ggcgtgcgtg tggaggtgct
    12361 taacgtcctt ggcgcgggag atgcgtttat gtctggcctg ctgcgcggtt acctgaacga
    12421 cgagggctgg gagcaggcgt gccgctacgc caacgcctgt ggggcgctgg tggtctcgcg
    12481 ccacggctgt gcaccggcga tgccgagcaa aattgagctg gatgattacc tctcccgcgc
    12541 cgcgctcgtt ccgcgcccgg acattgaccc gcgtcttaac catctgcacc gggtgaccac
    12601 ccgccgccgc gaatggccgg agctgtgcgt gatggcgttc gatcaccgca gtcaactgga
    12661 agatatggcg ctgcagtgcg gcgcgtcgct taagcgtatt ccggcgctga aacagctgat
    12721 cctgcaggcc agccgagagg cggcaagctc tgccgggctg gaggggaaag ccggcctgct
    12781 gtgcgatggc acctttggtc aggatgcgct gaacgccatt accggcgaag ggtggtggat
    12841 tggtcgtccc attgaactgc caggctcgcg tccgctggag atggagcacg gtaacattgg
    12901 tacccagctt atcagttggc cgcaggagca tgtggtgaag tgcctggtct ttttccatcc
    12961 ggaagatgcc cacggcttgc gtctggagca ggagcagaaa atcgccgagg tgtaccacgc
    13021 ctgctgtcag tccggacatg aactgctgct ggaggtgata ttacccgcca ctatgccgcg
    13081 cagtgacgaa ctttatctgc gtgccatttc ccgcttctac aaccttggca tttaccccga
    13141 ctggtggaaa ctgccgccgc tctccgccga aggctggacg gcactgagcg agattatcgc
    13201 gcgccgggac ccgcactgcc gcggcgtggt gatcctcggt ctggatgctc cggcggaaca
    13261 gctgcgtgcc gacttcaaag ctgccgcggg gcaggcgctg gtgaaaggct tcgccgtggg
    13321 gcgcacgctg tttggcgatg cctcccgcgc atggctgaaa cacgatattg acgatgcgca
    13381 gctggtggcg cgcatccggg acaactacct gcagcttatc gcctggtggc gcgagcgcgg
    13441 acacgcataa tggagacgac aatgagtgta caactgggca tcaacccgct gacgtggacg
    13501 aacgatgatc tgccttcact gggcgcggag acatctctgg agacctgcct gagtgaaggg
    13561 aaagaggccg gttttgctgg cttcgaactg ggcaataaat tcccgcgaga agcgcgcctg
    13621 ctcgggccca ttttgcagcg ccacgacctg cagttggtct ccggctggta ttccggccgc
    13681 ctgttggaac gcagtgtaga ggacgagatt gctgctgtgc agtcgcatct gacgctgctg
    13741 cgagagctgg gtgcaaaagt actggttttt gcggaagtga gtggctgcat tcacggtgag
    13801 cagcagacgc cggttcacct gcgcccacgt ttcccgcagg aatgctggaa agagtatggt
    13861 gagaagctca ccgtgttcgc ccgctatacg cagcaacagg gggtacagat tgcttaccac
    13921 catcatatgg gcacggtgat tgagtccgct caagacgtgg acaacctgat gctccacacg
    13981 ggtgaggagg ttggtttact gctggatacc ggccacctga cctttgccgg ggccgatccg
    14041 ctggcggtgg cacagcgatg ggcatcgcgc atcaatcatg ttcactgcaa agatgtgcgc
    14101 gccgacgtgc tggcggacgt caaaaaccgt aaaaccagct tcctcgacgc ggtgctgagc
    14161 ggcgtgttta ccgtgccggg tgacggctgc gtggattatc cgccgattat gcaactgctg
    14221 aaaacgcagg attatcacgg ttggctggtg gtggaggctg aacaggaccc ggcgatcgcc
    14281 catccgctga cctacgcccg tctgggatat aacaatctga gccgcctggc gcgcgacgcc
    14341 gggcttatct gaggaggtga catgtcacgt ctgttatcac gctggcaaca gccgaacgct
    14401 gaggggcgga ctcagtctgt cacgccggaa agcgccggat ggggatatgt tggctttgag
    14461 gcctatgaac ttgaggaagg gcagcaactg acgctgcccg ctgtcagtga agagcgctgt
    14521 ctggtgctgg tggccgggcg cgctttcatc agcactcctt ctgcacagtt tactgatatc
    14581 ggggagcgga tgagcccgtt cgagcgcatc aaaccttggg cggtttacgt caccccgcag
    14641 gaggcagtgc aggtgaaggc gctgacgaaa ctggagctgg cagtctgtac cgctccggga
    14701 aaagggacat acccgacgcg gttgattgca cctcaggata tcgatggcga agcgcgcggt
    14761 aacggccaca accagcgtta tgtgcataat attttgccgg aagacaagcc cgctgacagc
    14821 ctgctggtcg tcgaggtctg gaccaacgaa ggctgtacca gttcgtaccc gagccataaa
    14881 cacgatacga ataacccgcc tcaggagagc tatctggagg agacctatta ccatcgcctc
    14941 aacccggaac aggggttctg catgcagcgg gtgtataccg atgaccgcac acttgatgaa
    15001 tgtatggcgg tctataaccg tgacgtggtc atggtgccga aagggtacca cccggtggcg
    15061 acgatggccg ggtatgacag ttattacctt aacgtgatgg ccggaccagt acgtaaatgg
    15121 atattcacct gggaaaagga acactcatgg ataaacacag agtattctgc catttcttta
    15181 taaactgagt acctaagcta aaaaagggga atgactcccc ttttgtataa tatgaactcg
    15241 acaatgttat ttcaaagtct gagtgatgat ttttctctca ggcagtatgt tcctcaataa
    15301 ggatgagaat gtattctgtt cattggcata tgcatttata ttctaatgag ctgaatttta
    15361 taaaggttgt ggctattctg gagtataaat
//
LOCUS       DAPGUL010000106        15373 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.108, whole genome shotgun sequence.
ACCESSION   DAPGUL010000106 DAPGUL010000000
VERSION     DAPGUL010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15373
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.108"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..257)
                     /locus_tag="RHX21_003554"
     CDS             complement(<1..257)
                     /locus_tag="RHX21_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001458895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDV1988692.1"
                     /translation="MKRLQAFKFQLRPGDQQECEMRRFAGACRFVFNRALALQNENHE
                     AGNKYIPYGKMASWLVEWKNATETQWLKDSPSQPLQQSLKDL"
     gene            265..1227
                     /gene="tnpA"
                     /locus_tag="RHX21_003555"
                     /pseudo
     CDS             265..1227
                     /gene="tnpA"
                     /locus_tag="RHX21_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001349736.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(1436..2074)
                     /gene="leuE"
                     /locus_tag="RHX21_003556"
     CDS             complement(1436..2074)
                     /gene="leuE"
                     /locus_tag="RHX21_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine efflux protein LeuE"
                     /protein_id="HDV1988693.1"
                     /translation="MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVSSGMKGGY
                     LAACGVFIGDAVLMFLAWAGVATLIKTTPILFNIVRYLGAFYLLYLGSKILYATLKGK
                     NNEAKSDEPQYGAIFKRALILSLTNPKAILFYVSFFVQFIDVNAPHTGISFFILATTL
                     ELVSFCYLSFLIISGAFVTQYIRTKKKLAKVGNSLIGLMFVGFAARLATLQS"
     gene            complement(2201..3124)
                     /gene="dmlR"
                     /locus_tag="RHX21_003557"
     CDS             complement(2201..3124)
                     /gene="dmlR"
                     /locus_tag="RHX21_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310535.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator DmlR"
                     /protein_id="HDV1988694.1"
                     /translation="MNNLPLLNDLRVFMLVARRAGFAAVAEELGVSPAFVSKRIALLE
                     QTLNVVLLHRTTRRVTITEEGERIYEWAQRILQDVGQMMDELSDVRQVPQGMLRIISS
                     FGFGRQVVAPALSALAKAYPQLELRFDVEDRLVDLVNEGVDLDIRIGDDIAPNLIARK
                     LATNYRILCASPEFIAQHGAPKHLTDLSALPCLVIKERDHPFGVWQLRNKEGHHAIKV
                     TGPLSSNHGEIVHQWCLDGQGIALRSWWDVSENIASGHLVQVLPEYYQPANVWAVYVS
                     RLATSAKVRITVEFLRQYFAEHYPNFSLEHA"
     gene            3227..4312
                     /gene="dmlA"
                     /locus_tag="RHX21_003558"
     CDS             3227..4312
                     /gene="dmlA"
                     /locus_tag="RHX21_003558"
                     /EC_number="1.1.1.83"
                     /EC_number="1.1.1.85"
                     /EC_number="1.1.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional
                     D-malate/3-isopropylmalate/tartarate dehydrogenase"
                     /protein_id="HDV1988695.1"
                     /translation="MMKTMRIAAIPGDGIGKEVLPEGIRVLQAAAERWGFDLSFEQME
                     WASCEYYSHHGKMMPDDWHEQLSRFDAIYFGAVGWPDTVPDHISLWGSLLKFRREFDQ
                     YVNLRPVRLFPGVPCPLAGKQPGDIDFYVVRENTEGEYSSLGGRVNEGTEHEVVIQES
                     VFTRRGVDRILRYAFELAQSRPRKTLTSATKSNGLAISMPYWDERVEAMAENYPEIRW
                     DKQHIDILCARFVMQPERFDVVVASNLFGDILSDLGPACTGTIGIAPSANLNPERTFP
                     SLFEPVHGSAPDIYGKNIANPIATIWAGAMMLDFLGNGDERFQQAHNGILAAIEEVIA
                     HGPKTPDMKGNATTPQVADAICKIILR"
     gene            4563..6173
                     /gene="yeaV"
                     /locus_tag="RHX21_003559"
     CDS             4563..6173
                     /gene="yeaV"
                     /locus_tag="RHX21_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310537.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BCCT family transporter YeaV"
                     /protein_id="HDV1988696.1"
                     /translation="MMSNVKKKDVPLISISLVAILFIAAALSLFPQQSADAANAIYTF
                     VTRTLGSAVQVLVLLAMGLVIYLATSKYGNIRLGEGKPEYSTLSWLFMFICAGLGSST
                     LYWGVAEWAYYYQTPGLNIAPRSQQALEFSVPYSFFHWGISAWATYTLASLIMAYHFH
                     VRKNKGLSLSGIIAAITGVRPQGPWGKLVDLMFLIATVGALTISLVVTAATFTRGLSA
                     LTGLPDNFTVQAFVILLSGGIFCLSSWIGINNGLQRLSKMVGWGAFLLPLLVLIVGPT
                     EFITNSIINAIGLTTQNFLQMSLFTDPLGDGSFTRNWTVFYWLWWISYTPGVAMFVTR
                     VSRGRKIKEVIWGLILGSTVGCWFFFGVMESYAIHQFINGVINVPQVLETLGGETAVQ
                     QVLMSLPAGKLFLAAYLGVMIIFLASHMDAVAYTMAATSTRNLQEGDDPDRGLRLFWC
                     VVITLIPLSILFTGASLETMKTTVVLTALPFLVILLVKVGGFIRWLKQDYADIPAHQV
                     EHYLPQTPVEALEKTPVLPAGTVFKGDN"
     gene            6205..7329
                     /gene="yeaW"
                     /locus_tag="RHX21_003560"
     CDS             6205..7329
                     /gene="yeaW"
                     /locus_tag="RHX21_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine monooxygenase subunit YeaW"
                     /protein_id="HDV1988697.1"
                     /translation="MSNLSPDFVLPENFCANPQEAWTIPARFYTDQNAFEHEKENVFA
                     KSWICVAHSSELANANDYVTREIIGESIVLVRGRDKVLRAFYNVCPHRGHQLLSGEGK
                     AKNVITCPYHAWAFKLDGNLAHARNCENVANFDSDKAQLVPVRLEEYAGFVFINMDPN
                     ATSVEDQLPGLGAKVLEACPEVHDLKLAARFTTRTPANWKNIVDNYLECYHCGPAHPG
                     FSDSVQVDRYWHTMHGNWTLQYGFAKPSEQSFKFEEGTDAAFHGFWLWPCTMLNVTPI
                     KGMMTVIYEFPVDSETTLQNYDIYFTNEELTDEQKSLIEWYRDVFRPEDLRLVESVQK
                     GLKSRGYRGQGRIMADSSGSGISEHGIAHFHNLLAQVFKD"
     gene            7385..8350
                     /gene="yeaX"
                     /locus_tag="RHX21_003561"
     CDS             7385..8350
                     /gene="yeaX"
                     /locus_tag="RHX21_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine monooxygenase subunit YeaX"
                     /protein_id="HDV1988698.1"
                     /translation="MSDYQMFEVQVSQVEPLTEQVKRFTLVATDGKPLPAFTGGSHVI
                     VQMSDGDNQYSNAYSLLSSPHDTSCYQIAVRLKENSRGGSRFLHQQVKVGNRLTISTP
                     NNLFALIPSARKHLFIAGGIGITPFLSHMAELQHSDVDWQLHYCSRNPESCAFRDELV
                     QHPQAEKVHLHHSSTGTRLELARLLADIEPGTHVYTCGPEALIEAVRSEAARLDIAAD
                     TLHFEQFAIEDKTGDAFTLVLARSGKEFVVPEEMTILQVIENNKAAKVECLCREGVCG
                     TCETAILEGEADHRDQYFSDEERASQQSMLICCSRAKGKRLVLDL"
     gene            complement(8404..9519)
                     /gene="rnd"
                     /locus_tag="RHX21_003562"
     CDS             complement(8404..9519)
                     /gene="rnd"
                     /locus_tag="RHX21_003562"
                     /EC_number="3.1.13.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310540.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease D"
                     /protein_id="HDV1988699.1"
                     /translation="MITTDDALASLCEAVRAFPAIALDTEFVRTRTYYPQLGLIQLFD
                     GEHLALIDPLGITDWSPLKAILRDPSITKFLHAGSEDLEVFLNVFGELPQPLIDTQIL
                     AAFCGRPMSWGFASMVEEYSGVTLDKSESRTDWLARPLTERQCEYAAADVWYLLPITA
                     KLMVETEASGWLPAALDECRLMQMRRQEVVAPEDAWRDITNAWQLRTRQLACLQLLAD
                     WRLRKARERDLAVNFVVREEHLWSVARYMPGSLGELDSLGLSGSEIRFHGKTLLALVE
                     KAQTLPEEALPQPMLNLMDMPGYRKAFKAIKSLITDVSETHKISAELLASRRQINQLL
                     NWHWKLKPQNNLPELISGWRGELMAEALHNLLQEYPQ"
     gene            complement(9601..11292)
                     /gene="fadD"
                     /locus_tag="RHX21_003563"
     CDS             complement(9601..11292)
                     /gene="fadD"
                     /locus_tag="RHX21_003563"
                     /EC_number="6.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain-fatty-acid--CoA ligase FadD"
                     /protein_id="HDV1988700.1"
                     /translation="MKKVWLNRYPADVPTEINPDRYQSLVDMFEQSVARYADQPAFVN
                     MGEVMTFRKLEERSRAFAAYLQQGLGLKKGDRVALMMPNLLQYPVALFGILRAGMIVV
                     NVNPLYTPRELEHQLNDSGASAIVIVSNFAHTLEKVVDKTAVQHVILTRMGDQLSTAK
                     GTVVNFVVKYIKRLVPKYHLPDAISFRSALHNGYRMQYVKPELVPEDLAFLQYTGGTT
                     GVAKGAMLTHRNMLANLEQVNATYGPLLHPGKELVVTALPLYHIFALTINCLLFIELG
                     GQNLLITNPRDIPGLVKELAKYPFTAITGVNTLFNALLNNKEFQQLDFSSLHLSAGGG
                     MPVQQVVAERWVKLTGQYLLEGYGLTECAPLVSVNPYDIDYHSGSIGLPVPSTEAKLV
                     DDDDNDNEVPPGQPGELCVKGPQVMLGYWQRPDATDEIIKNGWLHTGDIAVMDEEGFL
                     RIVDRKKDMILVSGFNVYPNEIEDVVMQHPGVQEVAAVGVPSGSSGEAVKIFVVKKDP
                     SLTEESLVTFCRRQLTGYKVPKLVEFRDELPKSNVGKILRRELRDEARGKVDNKA"
     gene            complement(11497..12078)
                     /gene="yeaY"
                     /locus_tag="RHX21_003564"
     CDS             complement(11497..12078)
                     /gene="yeaY"
                     /locus_tag="RHX21_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Slp family lipoprotein YeaY"
                     /protein_id="HDV1988701.1"
                     /translation="MAVQKNVIKGILAGTFALMLSGCVTVPDAIKGSSPTPQQDLVRV
                     MSAPQLYVGQEARFGGKVVAVQNQQGKTRLEIATVPLDSGARPTLGEPSRGRIYADMN
                     GFLDPVDFRGQLVTVVGPITGAVDGKIGNTPYKFMVMQVTGYKRWHLTQQVIMPPQPI
                     DPWFYGGRGWPYGYGGWGWYNPGPARVQTVVTE"
     gene            complement(12118..12813)
                     /gene="tsaB"
                     /locus_tag="RHX21_003565"
     CDS             complement(12118..12813)
                     /gene="tsaB"
                     /locus_tag="RHX21_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HDV1988702.1"
                     /translation="MRILAIDTATEACSVALWNDGTVNAHFELCPREHTQRILPMVQD
                     ILTTSGTSLTDINALAYGRGPGSFTGVRIGIGIAQGLALGAELPMIGVSTLMTMAQGA
                     WRKNGATRVLSAIDARMGEVYWAEYQRDENGIWRGEETEAVLKPELVHERMQQLSGEW
                     VTVGTGWQAWPDLGKESGLVLRDGEVLLPAAEDMLPIACQMFAEGKTVAVEHAEPVYL
                     RNNVAWKKLPGKE"
     gene            complement(12871..14781)
                     /locus_tag="RHX21_003566"
     CDS             complement(12871..14781)
                     /locus_tag="RHX21_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HDV1988703.1"
                     /translation="MTDDFAPDGQLAKAIPGFKPREPQRQMAVAVTQAIEKGQPLVVE
                     AGTGTGKTYAYLAPALRAKKKVIISTGSKALQDQLYSRDLPTVSKALKYTGNVALLKG
                     RSNYLCLERLEQQALAGGDLPVQILSDVILLRSWSNQTVDGDISTCVSVAEDSQAWPL
                     VTSTNDNCLGSDCPMYKDCFVVKARKKAMDADVVVVNHHLFLADMVVKESGFGELIPE
                     ADVMIFDEAHQLPDIASQYFGQSLSSRQLLDLAKDITIAYRTELKDTQQLQKCADRLA
                     QSAQDFRLQLGEPGYRGNLRELLANPQIQRAFLLLDDTLELCYDVAKLSLGRSALLDA
                     AFERATLYRTRLKRLKEINQPGYSYWYECTSRHFTLALTPLSVADKFKELMAQKPGSW
                     IFTSATLSVNDDLHHFTSRLGIEQAESLLLPSPFDYSRQALLCVPRNLPQTNQPGSAR
                     QLAAMLRPIIEANNGRCFMLCTSHAMMRDLAEQFRATMTLPVLLQGETSKGQLLQQFV
                     SAGNALLVATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARMEDCRLRGGDPFD
                     EVQLPDAVITLKQGVGRLIRDADDRGVLVICDNRLVMRPYGATFLASLPPAPRTRDIA
                     RAVRFLAIPSSR"
     gene            14913..15257
                     /locus_tag="RHX21_003567"
     CDS             14913..15257
                     /locus_tag="RHX21_003567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416323.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HDV1988704.1"
                     /translation="MTIVRIDAEARWSDVVIHNNTLYYTGVPENLDADAFEQTANTLA
                     QIDAVLEKQGSNKSSILDATIFLADKNDFAAMNKAWDAWVVAGHAPVRCTVQAGLMNP
                     KYKVEIKIVAAV"
BASE COUNT         3737 a         4046 c         3790 g         3800 t
ORIGIN      
        1 aggtctttca gtgactgttg caatggctgt gagggagaat ctttaagcca ttgcgtttca
       61 gtggcatttt tccactcaac cagccaggaa gccattttcc cgtaagggat gtatttatta
      121 ccggcctcat gattctcatt ctgaagcgcc agagcacgat tgaaaacgaa acgacatgcg
      181 cctgcgaagc gcctcatttc acactcctgt tgatcacctg gtcttaactg gaatttaaat
      241 gcctgtagtc gtttcacagg ccaaatgata ctttggtctg tgaaaaaaga aaccgatatc
      301 cggcgtggaa ggcattgtgt tttcctgatg catgttcacc tggtctttgt caccagatac
      361 agacgtcaga tttttgacca tgacgcgaca gaaaaactac gcgcttactt ttcaaatgta
      421 tgtgctgatt ttgaagctga acttgttgaa atggatggcg aaccagatca cgtccatttg
      481 ttaattaact atcctcccaa actggcgata tccagtctgg taaacagcct caaaggcgta
      541 tcgggtaggt gactgcgacg agatcgacca gatattgcag tcaggtatta ctacaaaggc
      601 gttttgtgga gtgctggcta ttttgccagt agctgcggag gtgcgccaat atccgtcatc
      661 cgccaataca ttgaacaaca gcaaacacct ggtcaggtgg aaaaccgcgc cttatatccc
      721 tgccctgaag gatggggttt tacggcgcac cggataagaa cgcacggtat tcaccagatc
      781 ttttatcact tcagccgcca cttctggcac cagcaaagtc atcggcgtct ctgtttcata
      841 atcgacagaa acgccattgc tgttattggt gacggtcacg gtatacgttg ctttgcccat
      901 gattcatttc ccgttatgaa tgactttccg ttgttgcgca ccttccatca ggacttcagg
      961 agccacgaag aagtcaatgt tgaaataagt atcgtcagtc atggcttcaa tgttgtgcca
     1021 cttttctgga gggaacaccg caaactgccc cgcttcgata aggatcacct gatcaggctc
     1081 tgcactgtgt tcatcagcgt agccgagata tttgaccgcc ccatgcataa cggaaaggcg
     1141 tgggtaaacc cccgggcgcg ttcctttatc aagatgacgt tcgaatattc cggcaggcgc
     1201 agtttgttta ttccagaaag gcgttgagcg cgtatgaata taattctgtg ggatttgcag
     1261 catcctattc cctccttcgg ggaatgcgct gaaaacggtt tattccagcc gtttcagggt
     1321 acgcctgata atttgcattt taaataccat ttattggtta ctttttagca ccatatcaga
     1381 gaaaaatcag ggaggattac aagtggggag cccgcgacaa cgcgggctga atgtatcagg
     1441 attgcagcgt cgccagtcgg gcggcgaaac ccacgaacat caaaccaatc agtgagttgc
     1501 caactttagc cagtttcttt ttggtacgta tgtactgcgt gacaaaagca ccagaaataa
     1561 tcaggaagct caaatagcag aaactcacca gttccagcgt cgtcgccaga ataaagaatg
     1621 aaattcccgt atgtggggca ttaacatcga taaactgtac gaaaaacgac acatagaaca
     1681 aaatggcttt cggattagtc aggctcaaaa ttaacgcgcg tttaaaaatg gccccgtatt
     1741 ggggctcatc ggatttggcc tcgttatttt tacccttcag ggtcgcgtag agaattttac
     1801 tccccagata gagcaaataa aacgcaccaa gataacgtac aatgttgaat aatatcgggg
     1861 tggtcttaat taatgtcgcc actccagccc atgccagaaa catcaatact gcatcgccaa
     1921 taaatacacc gcaggccgca agataaccgc ctttcatacc gctactgacg ctatttttga
     1981 gtacaaacag ggtatttggc cctggcacca acacaataaa aatggcccca accagatagg
     2041 tccagtaatt cagaaccccg tattcagcga acacattaac ctctttaatt atctttcgat
     2101 catgcgcgat taaaggtgaa tatgctaacc aatctgtagc ggcttagaaa ggagaaaatc
     2161 aggttttaac ccgatatcaa cccgataatt gaatcattaa tcaggcatgc tccagtgaaa
     2221 aattcgggta gtgctcggca aaatactggc gtaaaaattc taccgttatc cgcactttcg
     2281 ctgacgtcgc cagccttgaa acataaacgg cccagacgtt cgctggctgg taatattccg
     2341 gtagcacttg cactaaatga ccactggcaa tgttttcgct aacatcccac caggagcgca
     2401 gagcaatccc ctgcccatcg agacaccact gatggacaat ttctccatga ttagacgaca
     2461 gtgggccggt gactttaatc gcatggtggc cttctttatt gcgtaattgc cagacaccaa
     2521 aaggatgatc gcgctcttta atgaccaggc acggcaatgc agaaagatcg gttaaatgtt
     2581 tcggcgcacc atgttgcgca ataaattccg gcgacgcgca gagaatgcgg taattagtcg
     2641 ccagtttgcg ggcgattaaa ttaggtgcga tgtcatcgcc aatgcgaata tcgagatcaa
     2701 caccttcatt gaccaaatcg accaaccggt cttccacatc aaaacgtaat tccagttgcg
     2761 gatacgcctt cgccagcgct gataacgccg gagccaccac ctgtcgtcca aaaccaaagc
     2821 tgctgataat acgcagcatc ccctggggca cctgacgcac gtcagaaagt tcgtccatca
     2881 tctgaccgac atcctgcaaa atccgctgcg cccattcata aatccgctct ccttcttcgg
     2941 taatggtgac gcggcgggtg gtgcggtgta acaacaccac gtttagcgtt tgctccagca
     3001 aggcgatgcg cttgctgacg aacgccggtg aaacgcccag ttcttccgcc acggcggcaa
     3061 aaccagcccg acgagccacc agcataaaga cgcgcaaatc attcagcagc ggtaaattat
     3121 tcatgattcg tgttttatgt ttcaccagtt acggggatta attccttttc agtcaattat
     3181 aggatggtga tgttgtcaat tttgatggtc aggaagtgag aacccaatga tgaaaacgat
     3241 gcgtattgct gcgatcccgg gagacgggat tggcaaagaa gtccttcctg aagggattcg
     3301 cgtgttacag gctgccgctg agcgctgggg cttcgacttg agttttgagc aaatggagtg
     3361 ggcgagctgc gagtattaca gccatcacgg taaaatgatg ccggacgact ggcatgagca
     3421 acttagccgt ttcgacgcca tctattttgg tgccgtcggc tggccggata ccgttccgga
     3481 ccatatttcg ttgtggggtt cgctgctgaa atttcgtcgt gaattcgacc agtacgtcaa
     3541 cctgcgcccg gttcgtctct ttcctggcgt tccctgcccg ctggcgggaa aacagcctgg
     3601 cgacatcgat ttttacgtgg tcagggaaaa caccgaaggc gaatattcct cgctcggcgg
     3661 tagagtgaat gaaggtacag agcatgaagt cgtcattcag gaatcggtat ttacgcgtcg
     3721 tggtgtcgat cgcattttgc gttatgcctt cgaacttgcg caaagccgcc cacgtaagac
     3781 gctaacttct gccactaaat caaacggttt agccatcagc atgccgtact gggatgagcg
     3841 agtggaagca atggccgaga attacccgga gatccgctgg gacaagcagc atattgatat
     3901 tctctgcgcg cgttttgtga tgcagccgga acgcttcgat gtggtggtgg cgtccaattt
     3961 atttggcgat atcctttccg atcttggccc ggcctgcacc ggcaccattg gcattgcccc
     4021 atccgccaac ctgaatccgg aacgcacttt cccgtcgctc ttcgagccag tccacggttc
     4081 cgcgccggat atctacggga aaaacattgc taaccctatc gccacgattt gggccggtgc
     4141 aatgatgctc gattttctcg gcaatggcga tgagcgtttc cagcaagcgc ataacggtat
     4201 tctggcagca attgaagaag tgattgctca cgggccgaaa acacctgata tgaaaggcaa
     4261 tgccaccacg ccacaggttg ccgacgcgat ttgcaaaatt attttgcgtt aaggtcaaac
     4321 cagtttattt gaaccgcgtc actgacgcgg tttttttatt cgttctttgc agtaaataac
     4381 ctgcgtcatt tcacctttta ttgtttccgt ttcgtgtttt atggctttcc gtattcttaa
     4441 ttgtttaatt tatgtaacat gcaaataatc aatttgttaa acacaacata caactcatta
     4501 ccctgcaaat aattacaact ggcaaaagcc agagacgggc ttttatgccc aggagatgac
     4561 tcatgatgag caatgttaag aaaaaagatg tgccgctgat aagcatcagc ctggtggcca
     4621 ttcttttcat cgcagctgca ttaagccttt tcccacaaca atcggccgac gcggccaacg
     4681 caatatacac ttttgttacg cgtacgttag gttccgccgt acaggtattg gttttgctgg
     4741 caatgggact ggtgatttat ttagccacca gtaaatacgg caatattcgt cttggcgaag
     4801 gaaaaccgga atacagcaca ctctcctggc tgtttatgtt tatttgtgcc ggtttaggtt
     4861 cttctacgct ttattggggg gttgctgaat gggcctatta ttatcaaacg cctggattaa
     4921 atatcgcacc gcgttcacaa caggcactcg aatttagcgt cccttactcc ttcttccact
     4981 ggggcatcag cgcctgggca acttatacgc tggcctcatt aatcatggct tatcactttc
     5041 atgtgcgtaa aaacaaaggt ctgagtcttt ccggcattat tgccgcgatt accggcgttc
     5101 gcccgcaagg cccatgggga aaactggttg atttgatgtt cctgatcgcc actgtcggcg
     5161 cactgactat ttcccttgtt gtcaccgcag caacctttac tcgtggactt tccgcgctga
     5221 ccggtttacc cgataacttc accgtgcagg catttgtgat cctgctttcc ggcggcattt
     5281 tttgcctaag ctcgtggatt ggtatcaaca acggtttgca acgtctgagc aaaatggttg
     5341 gctggggcgc gttcctgctg ccattactgg tgctgattgt cggcccaacc gaatttatta
     5401 ccaacagcat catcaatgcc atcggtctga ccacgcaaaa cttcctgcaa atgagcttat
     5461 tcaccgatcc gcttggcgat ggttcattta cccgcaactg gaccgttttc tactggctgt
     5521 ggtggatctc atacacccct ggcgtagcaa tgtttgtcac ccgcgtttcc cgcggtcgta
     5581 agattaaaga agttatctgg ggactgatcc tcggcagcac cgtcggttgc tggttcttct
     5641 tcggcgtaat ggaaagctat gccattcatc agtttatcaa tggcgtaatc aacgtcccac
     5701 aggtgctgga aacactgggc ggcgaaacag ctgtacagca agttctgatg tcgttgccag
     5761 ccggtaaatt gttcctcgcc gcatacctgg gcgtgatgat tattttcctt gcctcgcata
     5821 tggatgcggt ggcctacacc atggctgcga ccagtacgcg taatctccag gaaggtgacg
     5881 atcctgaccg tgggctgcgt cttttctggt gcgtggtgat cactctgatc ccgctttcca
     5941 tcttgtttac cggtgcttcg ctggaaacga tgaaaaccac cgtcgtgctc acagcccttc
     6001 ccttcctcgt cattttactg gtgaaagtcg gcggatttat tcgctggctg aaacaggatt
     6061 acgccgacat tccggctcat caagttgaac attatctccc gcagacaccg gttgaagccc
     6121 tggaaaaaac gccagtgctc cctgcgggaa ccgtattcaa aggcgacaac tgagcgccat
     6181 catcctaacg ataaaggtat ccctatgagc aatctgagcc ctgactttgt actacccgaa
     6241 aatttttgcg ctaacccgca agaggcgtgg accattcctg cccgttttta taccgatcag
     6301 aacgcgtttg aacacgaaaa agagaacgtc ttcgccaaaa gctggatttg cgtcgctcac
     6361 agcagcgaac tggcgaatgc caatgattat gtgacgcgtg agatcattgg tgaaagcatc
     6421 gtgctggtac gcggtcgtga taaggttttg cgcgcgttct ataacgtgtg tccgcaccgt
     6481 ggtcatcagt tgttgagcgg tgaaggaaaa gcaaaaaatg tgattacctg cccgtatcac
     6541 gcatgggcat tcaaactcga tggcaacctg gcccatgcac gtaactgcga aaacgtcgcc
     6601 aatttcgata gcgacaaagc gcaactggtt ccggtgcgtc tggaagaata tgccggattc
     6661 gtcttcatca acatggaccc caacgccacc agcgtagaag atcaattacc cggcctgggc
     6721 gcgaaagtgc tggaagcctg cccggaagtc cacgatctga aactggcggc ccgctttacc
     6781 acccgcacgc ctgccaactg gaagaacatt gtcgataact atctcgagtg ctatcactgt
     6841 ggtccggcgc atccaggttt ctccgactcc gtacaggttg atcgttactg gcacaccatg
     6901 cacggtaact ggacgctgca atacggtttc gccaaaccgt ccgaacagtc gtttaaattt
     6961 gaagagggta cggatgcggc attccacggt ttctggctgt ggccgtgcac gatgctgaac
     7021 gtcaccccga tcaaagggat gatgacggtc atttatgaat tcccggtgga ttctgaaact
     7081 accctgcaaa actacgatat ttacttcacc aatgaagagt taaccgacga gcaaaaatcg
     7141 ctgattgagt ggtatcgcga tgtgttccgt ccggaagatt tacgtctggt tgaaagcgta
     7201 cagaaagggc tgaaatcgcg tggctatcgt ggtcaggggc gcatcatggc cgacagtagc
     7261 ggtagtggca tttccgaaca tggtatcgcc catttccata atctgctggc gcaggtgttt
     7321 aaggactaat gacatcggcg gcggtatttt ccgccgctgg gctgattttt gatggagtac
     7381 agcaatgtca gactatcaaa tgtttgaagt acaggtgagc caggttgaac cccttaccga
     7441 acaggtgaaa cgcttcacgc tggtggcaac cgatggcaaa ccattacctg cgtttactgg
     7501 aggaagtcac gtcattgtgc agatgagcga tggtgataac cagtacagca atgcgtattc
     7561 actactgagt tcgccgcatg acacctcttg ttatcagatt gccgttcggc tgaaggaaaa
     7621 ctcgcgcggc ggttcccgct ttttgcatca gcaggtaaaa gtgggcaatc ggttaacgat
     7681 ttcaacgcct aataacctgt ttgcgctaat tccctcagcc agaaagcatc tgtttatcgc
     7741 gggcggtatt ggtatcaccc ctttcctgtc gcacatggca gagctgcaac acagcgacgt
     7801 cgactggcag ctacattact gctcgcgaaa tccagaaagt tgcgcatttc gtgatgagct
     7861 agtccagcat ccgcaggctg agaaagtcca tttgcatcat tcatcaaccg gaacacgact
     7921 ggaattagcg cgattattgg cggatatcga acctggcaca cacgtttata cctgtggccc
     7981 cgaggcgcta attgaagcgg taagaagtga agctgcgcgt ctggacatcg ccgccgatac
     8041 gctgcacttt gagcaatttg ctatcgaaga caaaaccggc gatgcattta ccctggtgct
     8101 tgcccgttcc ggaaaagagt ttgtggtgcc ggaagagatg actattttgc aggttattga
     8161 aaataataaa gccgcgaaag tggaatgttt atgtcgtgaa ggggtatgcg gaacctgcga
     8221 aacagcaata ctggaaggtg aagctgacca tcgggatcaa tattttagcg atgaagagcg
     8281 tgccagccag caaagtatgt tgatctgttg ttcgcgtgcg aagggtaaac gcctggtgtt
     8341 ggatttgtag tttgccgaag ccggatgtgg cgctgagcgc gcccagtccg gcttcggaag
     8401 attttactgc ggatattcct gcaataaatt gtgtaatgct tccgccatca gctcaccacg
     8461 ccagccggaa atcagctccg gcaaattgtt ctgcggtttc agtttccagt gccagttcag
     8521 cagttggttg atttgccgac gcgatgccag caattcggcg ctgatcttat gcgtttcgct
     8581 cacgtcagta atcagcgact taatcgcttt aaacgcttta cgataacccg gcatgtccat
     8641 caggttaagc atcggctgcg gtaaggcctc ttccggcaat gtctgcgctt tttccaccag
     8701 cgccagcagc gttttaccgt gaaagcggat ttcgctaccg gataaaccca ggctgtccag
     8761 ttcgcctaaa cttcccggca tataacgcgc taccgaccac aaatgctctt cacgcacgac
     8821 aaagttcacc gccagatcgc gctctcgcgc cttgcgcagt cgccagtcgg ctaacagttg
     8881 cagacaggcc agttggcgtg tgcgtaattg ccaggcattg gtgatatcac gccaggcatc
     8941 ttccggcgca acgacttcct gacgacgcat ttgcatcagg cggcattcat ccagcgccgc
     9001 aggtagccag ccggaggcct ccgtttctac cataagcttg gcggtgatcg gtaacagata
     9061 ccagacatcc gccgctgcgt attcacactg acgttcggtc agcggtctgg ccagccagtc
     9121 ggtgcgcgat tcactcttgt ccagcgtaac gccggaatac tcttccacca tggaagcgaa
     9181 accccatgac atcgggcgtc cgcagaaggc agcaaggatt tgcgtgtcaa tcaagggttg
     9241 tggtaattcg ccaaagacat tgaggaacac ttccagatct tcactgcctg catggagaaa
     9301 ttttgtgatg gacggatcgc gcaggatcgc tttcagcggt gaccagtcgg tgatcccgag
     9361 aggatcaatt agcgccagat gctcgccatc gaaaagttga atcaacccca gctgcgggta
     9421 ataagtgcgc gtacgaacaa attcagtatc cagggctatc gccggaaagg cacggacggc
     9481 ttcacacaaa gaagccagcg catcgtccgt ggtaatcatt tggtaattca aattgttttc
     9541 tctttagtgg gcgtcaaaaa aaacgccgga ttaaccggcg tctgacgact gacttaacac
     9601 tcaggcttta ttgtccactt tgccgcgcgc ttcgtcacgt aattctcgtc gcaaaatttt
     9661 tccgacgtta gatttcggta actcatcacg aaactccacc agcttcggta ctttgtagcc
     9721 cgtgagctga cggcggcaaa aggtcaccag tgactcttcg gtaagcgatg gatctttttt
     9781 cactacgaag attttcaccg cttcaccact ggagccggaa ggtacgccaa cagccgcgac
     9841 ttcctgtacg ccaggatgct gcatgacgac atcttcaatc tcgttgggat agacgttaaa
     9901 accggaaacc agaatcatgt cttttttacg atcgacaatg cgcaggaacc cttcttcatc
     9961 catcaccgca atgtcgccgg tgtgtaacca gccatttttg atgatctcat ctgtagcatc
    10021 cggacgctgc cagtaaccca gcatcacctg cggtcctttg acacaaagct cacccggttg
    10081 acccggtggt acttcattat cattatcatc atcatccacc agtttggctt ccgtcgacgg
    10141 caccggcaaa ccgatgctac cactatgata atcaatatca tatgggttaa cgctgaccag
    10201 cggcgcacac tcggtaaggc catagccttc cagcagatac tgtcctgtca gtttcaccca
    10261 acgctctgcc accacttgct gcactggcat ccctccgcct gcggaaagat gcagactgga
    10321 gaaatccagc tgctggaact ctttattgtt cagcaacgca ttgaacaagg tgttaacgcc
    10381 cgtgatagcg gtaaacggat atttcgctaa ctcttttacc aaccctggaa tatcgcgcgg
    10441 gttagtgata agcaggttct gcccacccag ttcgataaac agcaggcagt taatggtcag
    10501 ggcaaaaatg tgatacagcg gcagcgccgt caccaccagc tctttgcccg gatgcaacag
    10561 cggaccatag gtggcgttga cctgttccag gttcgccagc atattgcggt gagtcagcat
    10621 cgcgcctttc gccacacctg tggtgccgcc ggtgtattgc aggaaggcta aatcttccgg
    10681 caccagttcg ggtttgacgt actgcatccg gtagccgtta tgcagtgcgc tacgaaatga
    10741 aatggcatct ggcagatggt atttcggcac caaacgcttg atgtatttaa caacgaaatt
    10801 gactaccgtg ccttttgccg tagatagctg atcgcccata cgggtcagaa ttacgtgctg
    10861 aacggcggtt ttatcaacca ctttttccag tgtgtgagca aagttagaca cgataacaat
    10921 cgccgatgcg ccgctatcgt taagctgatg ctcaagctca cgcggggtat acaacgggtt
    10981 aacgtttacg acgatcatcc cggcacgcaa aatgccaaac agcgccaccg gatattgcaa
    11041 taaattaggc atcatcaacg caacgcgatc gcctttcttc agccccaacc cttgttgcaa
    11101 ataagcggca aacgcgcgac tgcgttcttc cagcttgcgg aaggtcatta cctcccccat
    11161 attcacaaac gcaggctgat cggcgtagcg cgcgaccgac tgctcaaaca tatctaccag
    11221 agattgataa cggtcagggt tgatctccgt cggaacgtcc gcgggataac ggttaagcca
    11281 aaccttcttc aattcttcac ctctaaaatg cgtgttcgtc gtcatcgcaa ccccaaatga
    11341 tatacatgcc gttaacataa tattaactca tcataccagc ttgataatta cccaacgaaa
    11401 aggttgcgaa gcgcgtcact atttattttt atctttaccg taagaatgca gaaacagcgg
    11461 accagccgct gtttcttttt ctttaaaaac aagcaattat tcagttacaa ctgtttgtac
    11521 tctcgcgggg ccgggattat accagcccca tccgccatag ccatagggcc agccacgacc
    11581 gccataaaac catggatcaa tcggctgagg cggcataatc acctgctggg ttaaatgcca
    11641 acgtttgtaa cccgttactt gcatcaccat aaatttatag ggcgtgttgc cgatttttcc
    11701 gtcaaccgca ccagtgattg gcccgactac cgtaaccagt tgtccacgga aatccaccgg
    11761 gtccagaaaa ccgttcatat cggcataaat gcgaccgcga gaaggttctc ccagcgtcgg
    11821 tctggctccg ctgtccagcg gtacggtagc aatttccagg cgggttttcc cttgctggtt
    11881 ttgtaccgca accactttgc caccaaagcg tgcctcctga ccaacgtaca gctgcggcgc
    11941 actcatcacc cgaactaaat cttgttgcgg cgtgggactg ctgcctttaa tggcgtccgg
    12001 cacagtgaca caaccgctca gcattagcgc aaacgtacct gccagtatgc ctttgataac
    12061 attcttttga accgccatgg tgcgactcct ttttttctca gggcatactc ttaagattca
    12121 ttctttgccc ggaagtttct tccatgcgac gttgttacgt aaataaaccg gttcggcatg
    12181 ttccaccgcc accgttttac cctcggcaaa catctgacac gcaatcggca gcatatcttc
    12241 cgccgctggc agtaaaactt ctccgtcgcg caaaaccagc ccgctctctt taccgagatc
    12301 cggccaggct tgccagcccg tccctaccgt tacccattcg ccggaaagct gttgcattcg
    12361 ttcatgaacg agttcgggtt tgagtacggc ttcggtttct tcaccgcgcc agataccgtt
    12421 ttcatcacgc tgatattcgg cccagtaaac ttcgcccatt cgcgcgtcaa tggctgacag
    12481 cacgcgggtt gcgccgtttt tgcgccacgc cccttgcgcc atcgtcatta gcgtggagac
    12541 gccaatcatc ggtaattccg cgccaagcgc cagcccttgc gcgatgccaa taccaatgcg
    12601 cacgccggta aagctaccgg ggccgcgccc gtaagccaga gcgtttatgt cagtcaggga
    12661 agttccgctg gtggtcagga tatcctgcac catcggtaag attcgttgag tatgttcacg
    12721 agggcaaagc tcaaaatgag cgttgacagt accgtcgttc cacagggcga cagagcaggc
    12781 ctctgtcgcg gtatcgatag ccagaattcg catgggtctt cgtgcttttt tcaataaaaa
    12841 ggcgcgcatc ataccatact ccgtaacaaa ttacctggag gatggtatcg caaggaaacg
    12901 aaccgcacgg gcaatgtcac gagtgcgtgg cgcgggcggc agactggcga gaaacgtcgc
    12961 gccgtaagga cgcatcacca gccgattgtc acaaatcacc agcacgccac gatcgtcggc
    13021 gtcgcgaatc agtcgcccta ccccctgttt gagagtaatg acggcatctg gtagttgcac
    13081 ttcatcgaac gggtcgccac cgcgcaaacg acaatcttcc atgcgcgctt ttaacagtgg
    13141 atcatccggc gaggtaaacg gcaacttgtc gataatcacc aatgacaatg tatcgccacg
    13201 cacgtccacc ccttcccaga aactactggt tgccacaaga agcgcgttac cggcgctgac
    13261 aaattgctgc aacagttgcc ctttgctggt ttccccctgc aacaaaacgg gaagcgtcat
    13321 ggtagcgcgg aactgctcgg ccagatcacg catcatggcg tgcgaggtac aaagcataaa
    13381 acaacgaccg ttgttagctt cgatgatcgg tcgcagcatt gccgctaact ggcgagcaga
    13441 acctggctgg ttggtttgcg gcagattgcg cggcacacag agtaacgcct ggcggctgta
    13501 atcaaacggg cttggcaata gcaacgactc cgcctgttct atcccaagcc gcgaggtgaa
    13561 atgatgcaga tcgtcgttca ccgacagcgt tgctgaggtg aagatccagc taccaggctt
    13621 ttgcgccatt aactctttga atttatccgc cacgctgagc ggcgtgagag ccagagtaaa
    13681 atggcgcgaa gtgcattcgt accagtagct gtagcccggc tgattgatct cttttagccg
    13741 cttcagccgt gtgcgataca acgtagcgcg ctcaaatgcc gcatccagca aggcggaacg
    13801 ccccagtgac agtttcgcca cgtcataaca aagttccagg gtgtcatcga gcagtaaaaa
    13861 tgcccgctga atttgcggat tagctaacag ctcacgcagg ttaccgcgat aacctggctc
    13921 accgagttgc agacgaaaat cctgcgcact ctgggcaaga cgatcagcgc acttttgtaa
    13981 ctgctgggtg tcttttaatt cggtgcggta agcgatggtg atgtcttttg ccaggtcgag
    14041 cagttgtcga ctggagagtg actgaccaaa atactggctg gcaatgtccg gtagctggtg
    14101 ggcttcgtcg aagatcatga cgtccgcttc cgggatcagt tcgccaaatc cactctcttt
    14161 aaccaccata tccgccagaa agagatgatg gtttaccacc accacatcgg cgtccatcgc
    14221 ttttttacgt gctttgacca caaagcaatc tttatacatc gggcagtcgc tgccaagaca
    14281 gttgtcgttg gtgctggtga ccagcggcca cgcctgtgaa tcttccgcca cgctgacgca
    14341 ggtgctgata tcaccatcga ctgtttgatt agaccaggag cgcagcagga tcacatcgct
    14401 taagatttgt accggcagat cgccccccgc cagcgcctgc tgttcgagac gttcgaggca
    14461 gaggtagttt gagcgccctt tcagcagcgc cacgttgccc gtatatttca atgcctttga
    14521 gactgttggc aaatcgcggc tgtagagctg atcctgcaac gcttttgagc cggtcgagat
    14581 aatgactttc tttttcgccc gcagcgcagg agccaggtaa gcgtaggttt tgcccgtacc
    14641 ggttcctgct tccaccacca gcggctggcc tttttctatc gcctgggtga cggctaccgc
    14701 catctgtcgc tgtggttctc gcggcttaaa gcctggtatc gctttcgcca gctgaccgtc
    14761 tggtgcaaaa tcgtccgtca cactaccccc tgttgatttg aacagggatt atgtcaggat
    14821 gagggcgctt tcgccagttg aagtggtgac ggcgacctca cattgtggca gtctttgcag
    14881 cacgaaaatg gaaggataat gaggacaaaa tgatgactat cgttcgtatc gatgctgaag
    14941 cccgctggtc tgatgtggta atccacaaca acacgctcta ctacactggt gtaccggaaa
    15001 acctcgacgc cgatgccttt gagcaaaccg ccaacacgct ggcgcagatt gatgccgtgc
    15061 tggaaaaaca gggcagcaat aaatcgagca ttctggatgc caccattttc ctggccgata
    15121 aaaacgactt cgcggcgatg aataaagcgt gggatgcctg ggttgtcgcg ggtcatgcgc
    15181 cggtgcgctg cacggtacaa gcgggtttga tgaacccgaa gtataaagtt gaaattaaga
    15241 ttgtggctgc ggtgtaagct ttatcgaagc aaaataagtc agacgataat ttatcgataa
    15301 tactggtcgg ttttacataa atcgaccaga gattaagata ttacctgttg atgctcctgc
    15361 taattcatta ttt
//
LOCUS       DAPGUL010000107        15314 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.109, whole genome shotgun sequence.
ACCESSION   DAPGUL010000107 DAPGUL010000000
VERSION     DAPGUL010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15314)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15314)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15314
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.109"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            10..660
                     /gene="zinT"
                     /locus_tag="RHX21_003568"
     CDS             10..660
                     /gene="zinT"
                     /locus_tag="RHX21_003568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-binding protein ZinT"
                     /protein_id="HDV1988705.1"
                     /translation="MAIRLHKLAVALGVFIVSAPAFSHGHHSHGKPLTEVEQKAANGV
                     FDDANVQNRTLSDWDGVWQSVYPLLQSGKLGPVFQKKADADKTKTFAEIKDYYHKGYA
                     TDIEMIGIEDGIVEFHRNNETTSCKYDYDGYKILTYKSGKKGVRYLFECKDPESKAPK
                     YIQFSDHIIAPRKSSHFHIFMGNDSQQSLLNEMENWPTYYPYQLSSEEVVEEMMSH"
     gene            1004..1534
                     /locus_tag="RHX21_003569"
                     /pseudo
     CDS             1004..1534
                     /locus_tag="RHX21_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416483.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b"
     gene            complement(2104..2193)
                     /locus_tag="RHX21_003570"
     tRNA            complement(2104..2193)
                     /locus_tag="RHX21_003570"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2157..2159),aa:Ser,seq:cga)
     gene            2287..3084
                     /gene="mtfA"
                     /locus_tag="RHX21_003571"
     CDS             2287..3084
                     /gene="mtfA"
                     /locus_tag="RHX21_003571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgsA anti-repressor MtfA"
                     /protein_id="HDV1988706.1"
                     /translation="MIKWPWKVQESAHQTALPWQEALSIPLLTGLTEQEQSKLVTLAE
                     RFLQQKRLVPLQGFELDSLRSCRIALLFCLPVLELGLEWLDGFHEVLIYPAPFVVDDE
                     WEDDISLVHNQRIVQSGQSWQQGPIVLNWLDIQDSFDASGFNLIIHEVAHKLDTRNGD
                     RASGVPFIPLREVAGWEHDLHAAMNNIQEEIELVGENAASIDAYAASDPAECFAVLSE
                     YFFSAPELFAPRFPSLWQRFCQFYQQDPLQRLHHANDTDSFSATNVH"
     gene            3185..3260
                     /locus_tag="RHX21_003572"
     tRNA            3185..3260
                     /locus_tag="RHX21_003572"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3218..3220,aa:Asn,seq:gtt)
     gene            3574..10650
                     /gene="yeeJ"
                     /locus_tag="RHX21_003573"
                     /pseudo
     CDS             3574..10650
                     /gene="yeeJ"
                     /locus_tag="RHX21_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416485.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="inverse autotransporter adhesin YeeJ"
     gene            complement(10912..11964)
                     /locus_tag="RHX21_003574"
                     /pseudo
     CDS             complement(10912..11964)
                     /locus_tag="RHX21_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310804.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 9 protein"
     gene            12279..13595
                     /gene="shiA"
                     /locus_tag="RHX21_003575"
     CDS             12279..13595
                     /gene="shiA"
                     /locus_tag="RHX21_003575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate transporter"
                     /protein_id="HDV1988707.1"
                     /translation="MDSTLISTRPDEGTLSLSRARRAALGSFAGAVVDWYDFLLYGIT
                     AALVFNREFFPQVSPAMGTLAAFATFGVGFLFRPLGGVIFGHFGDRLGRKRMLMLTVW
                     MMGIATALIGILPSFSTIGWWAPILLVTLRAIQGFAVGGEWGGAALLSVESAPKNKKA
                     FYSSGVQVGYGVGLLLSTGLVSLISMMTTDEQFLSWGWRIPFLFSIVLVLGALWVRNG
                     MEESAEFEQQQHYQAAAKKRIPVIEALLRHPGAFLKIIALRLCELLTMYIVTAFALNY
                     STQNMGLPRELFLNIGLLVGGLSCLTIPCFAWLADRFGRRRVYITGTLIGTLSAFPFF
                     MALEAQSIFWIVFFSIMLANIAHDMVVCVQQPMFTEMFGASYRYSGAGVGYQVASVVG
                     GGFTPFIAAALITYFAGNWHSVAIYLLAGCLISAMTALLMKDSQRA"
     gene            13697..15151
                     /gene="amn"
                     /locus_tag="RHX21_003576"
     CDS             13697..15151
                     /gene="amn"
                     /locus_tag="RHX21_003576"
                     /EC_number="3.2.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP nucleosidase"
                     /protein_id="HDV1988708.1"
                     /translation="MNNKGSGLTPAQALDKLDALYEQSVVALRNAIGNYITSGELPDE
                     NARKQGLFVYPSLTVTWDGSTTNPPKTRAFGRFTHAGSYTTTITRPTLFRSYLNEQLT
                     LLYQDYGAHISVQPSQHEIPYPYVIDGSELTLDRSMSAGLTRYFPTTELAQIGDETAD
                     GIYHPTEFSPLSHFDARRVDFSLARLRHYTGTPVEHFQPFVLFTNYTRYVDEFVRWGC
                     SQILDPDSPYIALSCAGGNWITAETEAPEEAISDLAWKKHQMPAWHLITADGQGITLV
                     NIGVGPSNAKTICDHLAVLRPDVWLMIGHCGGLRESQAIGDYVLAHAYLRDDHVLDAV
                     LPPDIPIPSIAEVQRALYDATKLVSGRPGEEVKQRLRTGTVVTTDDRNWELRYSASAL
                     RFNLSRAVAIDMESATIAAQGYRFRVPYGTLLCVSDKPLHGEIKLPGQANRFYEGAIS
                     EHLQIGIRAIDLLRAEGDRLHSRKLRTFNEPPFR"
BASE COUNT         4183 a         3620 c         3564 g         3947 t
ORIGIN      
        1 gaaactgttt tggcgattcg tcttcacaaa ctggctgttg ctttaggtgt ctttattgtt
       61 agcgctcctg ccttttcgca tggtcatcac tcacacggca aacccttaac agaggtcgaa
      121 caaaaagctg ctaatggtgt ttttgatgat gccaatgtac aaaaccgaac gctcagtgac
      181 tgggatggag tctggcaatc cgtttatcct ttactgcaaa gtggcaaact tggccccgtc
      241 tttcagaaga aagcggatgc agataaaacc aaaacatttg ctgaaattaa agattattat
      301 cacaaaggtt atgcgacaga tatcgagatg attggcattg aggacggcat tgttgaattc
      361 catagaaata atgaaacaac atcctgtaaa tatgattacg atggatacaa aatactcact
      421 tacaaatcag gtaagaaagg cgttcgttac ttattcgaat gtaaagatcc tgaaagcaaa
      481 gcccctaaat atatacaatt tagcgatcat ataattgcac cacgaaaatc atctcatttt
      541 cacattttta tgggtaatga ttcacagcaa tctttattaa atgaaatgga aaactggcca
      601 acgtattatc catatcagtt gagtagcgaa gaagtggtcg aggaaatgat gtctcattga
      661 gtattctcat gataacgcct cgatgccgct ttagtaagtc atcataacta ccactggtcc
      721 atccacaaac gccactgaac gcaagctagc tacagacacg ctcatcacta tgacgtgtct
      781 gtatattaaa taagctaacc cgcattgagt taaccaataa cggattccat acacaatacg
      841 gccaacagag aaagatacct gtgctcacgc cattgcttat attggctggt tacaatgtgc
      901 actatcaatt ttttaaataa caaattctta aaaccacatc tgtataagga atttttaagg
      961 ttcatgggat agcttgactg tgaaaattac aggagctaca aaaatgaacc gattctcaaa
     1021 aactcaaatt tatttacatt ggataacgct gcttttcatt gcaataacct atgccgcgat
     1081 ggaactccgt ggctggtttc ctaaaggtag tagtacttat ctgctgatgc gagaaataca
     1141 ttacaatgcg ggtatattcg tttgagtgtt aatgttttca cgcctgatta taaaacaccg
     1201 ttatagtgat ccttctattg tgccaccgcc acctgcctgg caaatgaaag cggcttcgct
     1261 aatgcacatc atgctttata taaccttcct tgcacttcct ctgctgggga ttgctttgat
     1321 ggcttacagt ggaaaatcgt ggagtttcct tggtttcaat gtgtctccct ttgttacccc
     1381 aaacagcgaa attaaagcac tgataaaaaa tattcacgaa acctgggcaa atataggcta
     1441 ctttttaatc gcagctcacg ctggcgcagc actctttcat cactacattc agaaagataa
     1501 tactctgtta cgaatgatgc ctcgccgcaa ataagtcgat cccctgacaa ggaaatgtga
     1561 accatggaca tcaacgcgtc ataaatgttt acgcaagtgc acaatgcacc ctttccacta
     1621 tcaacaagga ggagcagaaa ctgtgtaaat cgtacaatgg taagacttat caaaaataca
     1681 ggttaatttt ggtatttaaa ccttttttac ttgttagtat gatacaaagg ctttcaaaaa
     1741 agctgggaaa ttcaacaact cttggaaatt atggactttg tcccgcggct ttaatctgac
     1801 ggccgcgttc cttttttgac tcaattattg accccttctc tacgcaactt cagttcccac
     1861 caccaacttt gcggcagttt cataggatga atgtctaaaa gaataatggt gagcgataag
     1921 aaaacgactg aataactgca cattttcgct cgaaagcttc ctgtcagatc catagcgaat
     1981 caagtgctga atgtcacagt atcgaacaga aaacagtgac gatctaaccc ttcaagaata
     2041 ttctacgatt gttctgttta ggaaaagcaa ggcgggaagt cgggagataa gtcattgata
     2101 aagtggcgga gagaggggga tttgaacccc cggtagagtt gcccctactc cggttttcga
     2161 gaccggtccg ttcagccgct ccggcatctc tccgttcaga tggttgccat gatgccagga
     2221 aatttggcat tttaacagtc cctgtccgtg caattttgtt caagtgacga gtttgcgagc
     2281 aaaacgatga ttaagtggcc ctggaaagta caagaatcag cacatcaaac tgcccttccc
     2341 tggcaggaag cactatcgat ccccctttta acgggtctga cggaacagga acaaagcaaa
     2401 ttagtcactc ttgccgaacg ttttttacag caaaagcggc ttgttccttt acagggcttt
     2461 gaactggatt cattaagaag ctgccggata gcacttctat tttgcctacc cgttctggag
     2521 ttaggactgg aatggctgga tggttttcat gaagtcttaa tttatcctgc gccatttgtg
     2581 gtcgatgatg aatgggaaga cgatatcagt ctggtgcata accaacgtat tgttcagtca
     2641 ggtcagagct ggcagcaagg gcctatcgtt ttgaactggt tggatataca agattctttt
     2701 gatgcttctg gttttaacct gattattcat gaagtcgctc ataagctgga cacccgtaac
     2761 ggcgatcgcg ccagcggagt tccctttatt ccgttgcgtg aggttgctgg ctgggaacac
     2821 gatcttcatg ctgcaatgaa caacattcag gaagaaatcg aattggttgg cgagaatgcg
     2881 gcgagcattg atgcttatgc agccagcgat cctgctgaat gttttgccgt actttctgaa
     2941 tatttcttta gcgccccaga actttttgct cctcgtttcc cttcattgtg gcaacgtttc
     3001 tgccaatttt atcaacaaga tcctttgcag agactgcatc acgctaatga tacagactcg
     3061 ttttcggcga cgaatgttca ttaattaaca actttgcaga ttaattaacc aattgaaatg
     3121 acttatgaaa tttagtgttg acagacaagg taccgctaag taatattcgc cccgttcaca
     3181 cgattcctct gtagttcagt cggtagaacg gcggactgtt aatccgtatg tcactggttc
     3241 gagtccagtc agaggagcca aattctaaaa attcgctttt ttagcgcaat gtcactgacc
     3301 ttagttgaac attgtttttt aacggatagc gggtttttaa catcttaagc gccctcgacc
     3361 tttatggttg agggcgtttt gctatgaacg ccatcaccat tttcccctcg attataaaac
     3421 ttgagttatt cagtagtctc ccctcttgca actcacaccc aaaactgcct aacgaaaagt
     3481 tattaatttt caatcatatt gctatcagta tttacatttt ttcgctgtgc tagaaagggc
     3541 gcatttatgt tagctcgttc agggaaggta agcatggcta cgaagaagag aagtggagaa
     3601 gaaataaatg accgacaaat attatgcggg atgggaatta aactacgccg cttaactgcg
     3661 ggtatctgtc tgataactca acttgcgttc cctatggctg cggcagcaca aggtgtggta
     3721 aacgccgcaa cccaacaacc agttcctgca caaattgcca ttgcaaatgc caatacggtg
     3781 ccctacaccc ttggagcgtt ggaatcggcc caaagcgttg ccgaacgttt cggtatttcg
     3841 gtggctgagt tacgcaaact caaccagttt cgtacgtttg ctcgaggttt tgataatgtc
     3901 cgccagggtg atgaactgga tgtcccggca caagttagtg aaaaaaaatt aaccccgccg
     3961 ccgggtaata gcagtgacaa cctcgagcaa cagatagcca gtacttcaca gcaaatcggg
     4021 tctctgctcg ccgaagatat gaacagcgag caagcggcaa atatggcgcg tggatgggcc
     4081 tcttctcagg cttcaggcgc aatgacagac tggttaagcc gcttcggtac cgcaagaatc
     4141 acgctgggcg tggatgaaga ttttagcctg aagaactccc agttcgattt tctccatccg
     4201 tggtataaaa cgcctgataa tctctttttc agtcagcata ctctccatcg tactgacgag
     4261 cgtacgcaga ttaacaacgg cttaggttgg cgtcatttca ctcccacatg gatgtcgggc
     4321 atcaacttct ttttcgacca cgatcttagc cgttaccact cccgcgccgg cattggcgcg
     4381 gagtactggc gcgactatct aaaattaagc agtaacggct atttgcgact gaccaactgg
     4441 cgcagcgcac ctgaactgga caacgattat gaagcacgcc cggccaatgg ctgggatgta
     4501 cgcgcagaaa gctggctacc cgcctggccg caccttggcg gtaaactggt ctatgaacag
     4561 tattatggcg atgaagtggc cctgttcgat aaagacgatc ggtaaagtaa tcctcatgcc
     4621 ataaccgctg gacttaacta tacccccttc ccgctgatga ccttcagcgc ggagcaacgc
     4681 cagggtaaac agggcgaaaa tgacacccgt tttgccgtcg attttacctg gcaacctggc
     4741 agcgcaatgc agaaacagct tgacccgaat gaagtcgctg cacggcgtag ccttgcaggc
     4801 agccgttatg atctggtgga tcgcaacaac aatatcgttc tggaatatcg caaaaaagaa
     4861 ctggttcgcc tgaccctgac agaccccgtg acagggaagt caggagaagt gaaatcactg
     4921 gtttcgtcgc tacaaaccaa atatgccctg aaaggctata acgtcgaagc caccgcactg
     4981 gaagctgccg gtggcaaagt ggtcacaacg ggtaaagata ttctggttac cctgccggct
     5041 taccggttca ccagtacgcc agaaaccgat aacacctggc cgattgaagt caccgccgaa
     5101 gatgtcaaag gcaatttgtc gaatcgtgaa cagagcatgg tggtcgttca ggcacctacg
     5161 ctaagccaga aagattcctc ggtatcgtta agtacccaaa cattgaacgc ggattcccat
     5221 tcaaccgcca cactgacttt tattgcgcat gatgcagcag gtaatcctgt tgtcgggctg
     5281 gtgctctcga cgcgtcacga aggtgttcag gacatcaccc tttctgactg gaaagataat
     5341 ggtgacggaa gctataccca gatcctgacc acaggagcga tgtctggcac gctgacgctg
     5401 atgccacagc tgaatggtgt ggatgcggct aaagcccccg ccgtggtgaa tatcatttct
     5461 gtttcgtcat cccgaactca ctcgtcaatt aagattgata aggaccgtta tctctccggc
     5521 aatcctatcg aggtgacggt agaactgaga gatgaaaatg acaaacctgt taaggaacaa
     5581 aaacagcaac tgaataacgc agtcagcatc gacaacgtga aaccaggagt cactacagac
     5641 tggaaagaaa ccgcagatgg cgtctataag gcgacctata ccgcctatac caaaggcagt
     5701 ggacttactg cgaagctatt aatgcaaaac tggaatgaag atttgcatac cgctggattt
     5761 atcatcgacg ccaacccgca gtcagcgaaa attgcgacat tatctgccag caataatggt
     5821 gtgctcgcca atgagaatgc agcaaacacc gtctcggtca atgtcgctga tgaaggaagc
     5881 aacccaatca atgatcatac cgtcacgttt gcggtattaa gcggatcggc aacttccttc
     5941 aacaatcaaa acaccgcaaa aacggatgtt aatggtctgg cgacttttga tctgaaaagt
     6001 agtaagcagg aagacaacac ggttgaagtc acccttgaaa atggcgtgaa acaaacgtta
     6061 atcgtcagtt ttgtcggcga ctcgagtacc gcgcaggttg atctgcagaa gtcgaaaaat
     6121 gaagtggttg ctgacggcaa tgacagcgtc acaatgaccg cgaccgtccg ggatgcaaaa
     6181 ggcaacctgc tcaatgacgt catggtcact ttcaatgtta attcagcaga ggcgaaactg
     6241 agccaaaccg aagtgaatag ccacgacggg atcgccacag ctacgctgac cagtttgaaa
     6301 aatggtgatt atagggttac ggcctctgtg agctctggtt cccaggctaa tcaacaggtg
     6361 aattttatcg gtgatcaaag tactgctgcc ctgaccctca gtgtgccttc aggtgatatc
     6421 accgtcacca acacagctcc gcaatatatg actgcaacct tgcaggataa aaatggcaac
     6481 ccactaaaag ataaagaaat caccttctct gtgccaaacg acgtcgcaag taagttctcg
     6541 attagcaacg gaggaaaagg catgacggat agtaacgggg ttgcaatcgc ctccctgacc
     6601 ggcacgttag cgggcacgca tatgatcatg gctcgtctgg ctaacagcaa tgtcagcgat
     6661 gcacagccaa tgacgtttgt ggcggataaa gacagagcgg ttgtcgtttt gcaaacatcg
     6721 aaagcggaaa tcattgggaa tggcgtggat gagacaactc tgacagcaac agtgaaagat
     6781 ccgtcgaatc atccggtggc ggggataacg gtaaacttca ccatgccaca ggacgttgcg
     6841 gcaaacttta cccttgaaaa taacggtatt gccatcactc aggccaatgg ggaagcgcat
     6901 gtcacgctga aaggtaaaaa agcgggcacg catacggtta ccgcaacgct gggtaataac
     6961 aataccagtg attcgcagcc ggtaacattt gtggcggaca aagcctcggc tcaggttgtc
     7021 ctgcagatat caaaagatga gatcacaggt aatggcgtcg atagcgcaac gctaactgca
     7081 acggttaaag atcagttcga caatgaggtg aataatcttc cggtaacatt cagctcagcc
     7141 tcttcaggac tcaccctgac cccgggagta agtaatacca acgagtctgg catcgcgcag
     7201 gccactctcg caggcgttgc ctttggtgag aagacggtta ctgcatcact ggctaataat
     7261 ggtgccagcg acaacaaaac tgtgcatttt attggcgaca cagcggcggc aaaaattatc
     7321 gagttgacgc ctgtcccaga cagcataatc gccggtaccc cgcagaacag ctccggcagc
     7381 gtcatcaccg ccacagtcgt tgataataat ggctttccgg tgaaaggtgt gactgtgaac
     7441 ttcaccagca acgcagcgac agccgaaatg acgaacggcg gtcaagccgt gacgaacgaa
     7501 cagggtaagg ctaccgtcac ttataccaat acccgctcct cgatagaatc aggagcgaga
     7561 ccggataccg ttgaggccag tctggaaaat ggtagctcca cgcttagcac atcaattaat
     7621 gtcaacgctg atgcgtctac ggcacatctc accttgctac aggcactttt tgatacagtc
     7681 tccgcaggcg agacaaccag tctgtatatt gaggtgaagg ataattacgg caacggtgtc
     7741 ccccagcagg aggtaaccct cagcgtttca ccaagtgaag gcgtgacccc cagtaataac
     7801 gctatatata ctaccaacca cgacggcaat ttttacgcaa gctttaccgc tacaaaagcc
     7861 ggggtttatc aattgacggc aaccctcgaa aatggcgatt cgatgcaaca aacagtgacc
     7921 tatgtgccga acgtcgcgaa tgctgaaatc acgctggcag cctcgaagga tccggtgatt
     7981 gccgacaata acgatctcac gacactaaca gcaacagtcg ctgatacaga gggcaatgcg
     8041 atagccaaca ctgaggtaac atttactctg ccggaagatg tgaaggcgaa cttcacgctg
     8101 agcgatggcg gtaaagtgat tactgatgct gaaggcaaag cgaaagtcac gctgaaaggt
     8161 acaaaagcag gcgctcatac tgttacagca tcgatgactg gcggtaagag tgagcagttg
     8221 gtggtgaact ttattgcgga tacgctcact gcgcaggtta atcttaacgt taccgaggac
     8281 aattttatcg ctaataacgt cgggatgacc aggctgcagg caacagtgac tgatggaaac
     8341 ggcaacccgt tagccaatga ggcggtgaca ttcacgctac cggcagatgt gagcgcaagc
     8401 tttactctcg gacaaggcgg ttccgccatt actgatatca acggcaaggc tgaagttaca
     8461 ctgagcggta caaaatccgg cacctacccc gtgacagtta gcgtgaacaa ttatggtgtc
     8521 agtgatacga aacaggtgac tttgattgcc gatgctggta ccgcaaaact agcctcctta
     8581 acctctgtat actcattcgt cgtcagcacg accgagggcg caaccatgac ggcaagcgtc
     8641 actgacgcta acggcaaccc ggtagaaggc ataaaagtta atttccgcgg aacctccgtc
     8701 acgctaagca gcaccagcgt tgaaacggat gatcggggtt tcgctgaaat tcttgtgaca
     8761 agcaccgagg tcggactgaa aacagtttca gcctctctgg cagataaacc tactgaagtc
     8821 atctcgcgat tactgaatgc cagtgcagat gttaattctg cgacgattac cagtctggag
     8881 ataccggaag gtcaggtaat ggtcgcacaa gacgtagcag ttaaagctca cgttaacgac
     8941 cagtttggca acccggttgc gcatcaaccc gtgacattca gtgcagagcc atcctcgcaa
     9001 atgatcatca gccagaatac ggtctctact aatacgcagg gtgtagccga ggtcaccatg
     9061 acgcccgaaa gaaacggttc gtatatggtg aaagcatccc tgccgaatgg agcctcactt
     9121 gagaaacaac tggaggctat tgatgaaaaa ctgacactca cggcgtccag tccgcttatc
     9181 ggtgtctatg cccctacagg cgctactctg acggcaacgc taacctctgc aaatggcact
     9241 ccagtggagg gtcaggtcat caactttagc gtaacgccag aaggggcgac gttaagtggc
     9301 ggaaaagtga gaactaactc ttcaggtcag gctccagtcg ttttgaccag caataaagtc
     9361 ggtacatata cggtgactgc atctttccat aacggcgtaa caatacagac acagacaacc
     9421 gtgaaagtca ctggcaactc aagcaccgcc catgttgcta gctttatcgc tgatccatcg
     9481 actatcgccg ccaccaacac tgatttaagt accttaaagg caacggttga ggatggcagt
     9541 ggtaacctga tcgaaggtct cactgtgtac ttcgccttaa aaagcggctc tgccacatta
     9601 acgtcattaa cagcggtgac cgatcaaaac ggaatcgcga caacaagcgt gaaaggagcg
     9661 atgacaggta gcgtcacggt aagcgcagtc acgaccgctg gtggaatgca aacagtagat
     9721 ataacgctgg tggctggccc ggcagacacc tcgcagtccg tccttaagag caatcggtca
     9781 tcactgaaag gggactatac cgatagtgct gaattacgtc ttgttctgca cgatatatca
     9841 ggcaatccga tcaaagtttc tgaagggatg gaatttgtgc aatcaggtac taacgtgccc
     9901 tatataaaaa ttagcgcaat tgattacagt ctaaatatca acggtgatta caaagccact
     9961 gttacaggag gcggagaggg tatcgcaacg ctgatccctg tattgaatgg tgttcatcaa
    10021 gcaggtctga gtaccacaat acaattcact cgcgcagaag acaaaataat gagcggtaca
    10081 gtatcagtca atggtactga cctaccgaca actacattcc cttcgcaggg gttcaccggg
    10141 gcgtattatc agttgaataa tgacaacttt gccccaggaa aaacggcggc tgattatgag
    10201 ttttcaagct ctgcctcctg ggtcgatgtt gatgctaccg gtaaagtgac atttaaaaat
    10261 gtcggcagca attcggaaag gattacggcg acgccaaaat caggaggccc tagctatgta
    10321 tacgaaatcc gtgtgaagag ttggtgggtg aacgccggcg aggctttcat gatatacagc
    10381 cttgctgaaa atttttgcag cagcaatggc tacacgctcc ccagagcaaa ctatttaaac
    10441 cactgtagtt cccgaggcat cgggtcactg tacagtgaat ggggagatat ggggcattac
    10501 acgactgacg ctggttttca atcaaatatg tattggtcat ctagtcccgc aaactcaagc
    10561 gaacaatacg tagtttccct ggcaacaggt gatcaaagcg tatttgaaaa gcttgggttt
    10621 gcttatgcga catgttataa aaacctgtga ttttccgtta taatttctta aagagtgttc
    10681 cattcggggc actctttttt acattccctc tacagaacta gcccttctct cacagaaaat
    10741 gaataaataa aaatgcggca ccgccagaat cgcgttcgat gtgactatga tcattttcgg
    10801 tgagtactgc tttgatctaa aggctggttt tctgtgatga ttgaccagcc tcagagtatt
    10861 gatgacacca ccgttcataa cagatcggca ttactatgca taagtactgt ctcatattct
    10921 cgccaaaaca ctttttaatg cctttgcgaa ttcatccaga cttatattgt caattttttg
    10981 cccaacgacg actgactccg agacatcggc cattgcgggc catcgcgttt tgtaatcagc
    11041 ataaattgca acaacagagg tattataggc acttgccata tgtaatattg aggtgtcagg
    11101 agttattgcg atataagcat cttttatgat tgctgctgaa cgtttaatcg agggtggtaa
    11161 ggataaacgg tagacattat tataacaatc cactaatgcc ctggctttat cttcaccttt
    11221 gggtccatga acgatcacta ttggtatatc tgtttcactt taaatttttg ctattagatt
    11281 ttctgcaatc gataatgaaa atgtacgttc ctgcgagcta ccttctaaat tgaacgcaat
    11341 gtaagatcct aacgatcgca tttcctcgcg cacctcatcg agtacatcct cacttagtgg
    11401 caattcatat attggcctga ctgctggaaa acccgcctca cgcatcataa atgcccatgt
    11461 cataggtacg ggagcccgga gtttctgatc catacgggac gcgttcttgc acaaagggga
    11521 gaagcaattc atggttatac caacaacctg aaaattcgtt tttgctttca actgactgat
    11581 aaataacatc gttttcaggt tctttttacg catcccctca atgcaaagat tcggcgtacc
    11641 gtattgctgt gttatgttct ttgctaaatc ttttatttct tttaatgttg cgtgatcctg
    11701 catagtcatt gtgactaatg ttaatttagt ctgttcaagt ttaagcgcat taaagacttc
    11761 taaattaatt gtcgacgtta caattaaaag atgcttaatt ttatgcaatt caagcgcccg
    11821 aataacagga aagatggcca tagcatcgcc aatctgatcg ggaatatgga tgacaacaaa
    11881 gtctgttttt tcaatattga aattataagc tttataatcg tagtaactaa atgcaatacg
    11941 tctcaacaat gatgctaaaa acatacctaa cctcgcctcc ctactggtta taatgcaatg
    12001 cagtctatca gactcatcag ggtgccattt tgtgcatatg cggactttta tgtttcatat
    12061 ctctaacctg tgggtcctct gcttaatcct taaacaacac cagcaactcc tgcgctttca
    12121 tcttccatcg aatttttcat gttgccgcta atcagccata aaatcatttg cagatgcgct
    12181 ctgtcgaggt agtctcataa ggttcgttta tagatcgacg gcaatgtgag ttaccttttc
    12241 catactaatt ataaaaagac agtacaaaca ggatcattat ggactccacg ctcatctcca
    12301 ctcgtcccga tgaagggacg ctttcgttaa gtcgcgcccg acgagctgcg ttaggcagct
    12361 tcgctggtgc cgtcgtcgac tggtatgatt ttttactcta tggcatcacc gccgcactgg
    12421 tgtttaatcg cgagtttttc ccgcaagtaa gcccggcgat gggaacgctc gccgcatttg
    12481 ctacctttgg cgtcggattt cttttccgtc cgctcggcgg tgtcattttc ggtcactttg
    12541 gcgaccgact gggacgtaag cgcatgttaa tgctgaccgt ctggatgatg ggcatcgcga
    12601 cagccttgat tggtattctt ccttcattct cgaccattgg gtggtgggca cctattttgc
    12661 tggtgacact gcgtgccatt cagggatttg cagtcggcgg cgaatgggga ggcgcggcgt
    12721 tgctttccgt tgaaagtgca ccgaaaaata aaaaagcctt ttacagtagc ggtgtacaag
    12781 ttggctacgg tgtaggttta ctgctttcaa ccggactggt ttcattgatc agtatgatga
    12841 cgactgacga acagttttta agctggggct ggcgcattcc tttcctgttt agcatcgtac
    12901 tggtactggg agcattgtgg gtgcgcaatg gcatggagga gtccgcggaa tttgaacaac
    12961 agcaacatta tcaagctgcc gcgaaaaaac gcatcccggt tatcgaagcg ctgttacgac
    13021 atcccggtgc tttcctgaag attattgcgc tacgactgtg cgaattgctg acgatgtaca
    13081 tcgttactgc ctttgcactt aattattcaa cccagaatat ggggctaccg cgcgaacttt
    13141 tccttaatat tggtttgctg gtaggtggat taagctgcct gacaattccc tgttttgcct
    13201 ggcttgccga tcgttttggt cgccgtaggg tttatatcac aggtacgtta atcggaacgt
    13261 tgagcgcatt tcctttcttt atggcgcttg aagcacaatc tattttctgg atagttttct
    13321 tctccataat gctggcaaac attgcgcatg acatggtggt gtgtgtgcaa caaccgatgt
    13381 ttaccgaaat gtttggtgcc agttatcgct atagtggcgc tggagtcggt tatcaggttg
    13441 ccagtgtggt tggcggtgga tttacacctt ttattgccgc tgcactcatc acttactttg
    13501 ccgggaactg gcatagcgtc gccatttatt tgctggctgg atgcctgatt tccgcaatga
    13561 ccgctttgtt gatgaaagac agtcaacgcg cttgatagcc tggcgaagat catccgatct
    13621 tcgccttaca cttttgtttc acatttctgt gacatactat cggatgtgcg gtaattgtat
    13681 ggaacaggag acacacatga ataataaggg ctccggtctg accccagctc aggcactgga
    13741 taaactcgac gcgctgtatg agcaatctgt agtcgcatta cgcaacgcca ttggcaacta
    13801 tattacaagt ggcgaattac ctgatgaaaa cgcccgcaaa caaggtcttt ttgtctatcc
    13861 atcactgacc gtaacctggg acggtagcac aaccaatccc cccaaaacgc gcgcatttgg
    13921 tcgctttacc cacgcaggca gctacaccac cacgattact cgccctactc tctttcgttc
    13981 gtatcttaat gaacaactta cgttgctgta tcaggattat ggtgcgcata tctcagtgca
    14041 accctcgcag catgaaatcc cttatcctta tgtcatcgat ggctctgaat tgacacttga
    14101 tcgctcaatg agcgctgggt taactcgcta cttcccgaca acagaactgg cgcaaattgg
    14161 cgatgaaact gcagacggca tttatcatcc aactgaattc tccccgctat cgcattttga
    14221 tgcgcgccgc gtcgattttt ccctcgcacg gttgcgccat tataccggta cgccagttga
    14281 acattttcag ccgttcgtct tgtttaccaa ctacacacgt tatgtggatg aattcgttcg
    14341 ttggggatgc agccagatcc tcgatcctga tagtccctac attgcccttt cttgtgctgg
    14401 cgggaactgg atcaccgccg aaaccgaagc gccagaagaa gccatttccg accttgcatg
    14461 gaaaaaacat cagatgccag catggcattt aattaccgcc gatggtcagg gtattactct
    14521 ggtgaatatt ggcgtgggac cgtcaaatgc taaaaccatc tgcgatcatc tggcagtgct
    14581 acgcccggat gtctggttga tgattggtca ctgtggcgga ttacgtgaaa gtcaggccat
    14641 tggcgattat gtacttgcac acgcttattt acgcgatgac cacgttcttg atgcggttct
    14701 gccgcccgat attcctattc cgagcattgc tgaagtgcaa cgtgcgcttt atgacgccac
    14761 caagctggtg agcggcaggc ccggtgagga agtcaaacag cggctacgta ctggtactgt
    14821 ggtaaccaca gatgacagga actgggaatt acgttactca gcttctgcac ttcgttttaa
    14881 cttaagccgg gccgtagcaa ttgatatgga aagtgcaacc attgccgcgc aaggatatcg
    14941 tttccgcgtg ccatacggga cactactgtg tgtttcagat aaaccgttgc atggcgagat
    15001 taaacttccc ggccaggcta accgttttta tgaaggcgct atttccgaac atctgcaaat
    15061 tggcattcgg gcgatcgatt tgctgcgcgc agaaggcgac cgactgcatt cgcgtaaatt
    15121 acgaaccttt aatgagccgc cgttccgata ataagttctg aaccttctta tcagaaatag
    15181 atgtgaagga gtaagtaaga cacctggcaa atagcctgca ataatcgtgg gctgtttgct
    15241 tccttgggcg gatacgagtt ttattatcgt cttaatgatt tccacatatt aaaagcaagt
    15301 atgctttcaa aaca
//
LOCUS       DAPGUL010000108        15288 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.110, whole genome shotgun sequence.
ACCESSION   DAPGUL010000108 DAPGUL010000000
VERSION     DAPGUL010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15288
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.110"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(1..1830)
                     /locus_tag="RHX21_003577"
                     /pseudo
     CDS             complement(1..1830)
                     /locus_tag="RHX21_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310454.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ShET2/EspL2 family type III secretion system
                     effector toxin"
     gene            2354..4282
                     /gene="thrS"
                     /locus_tag="RHX21_003578"
     CDS             2354..4282
                     /gene="thrS"
                     /locus_tag="RHX21_003578"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006894721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HDV1988709.1"
                     /translation="MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGEL
                     VDACDLIENDAQLSIITAKDEDGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGF
                     YYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSIL
                     DENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRI
                     YGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRE
                     LEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNC
                     PGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQ
                     IRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNI
                     PFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPV
                     MIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAG
                     IRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEV
                     IEKLQQEIRSRSLKQLEE"
     gene            4286..4828
                     /gene="infC"
                     /locus_tag="RHX21_003579"
     CDS             4286..4828
                     /gene="infC"
                     /locus_tag="RHX21_003579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HDV1988710.1"
                     /translation="MKGGKRVQTARPNRINGEIRAQEVRLTGLEGEQLGIVSLREALE
                     KAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGT
                     DEGDYQVKLRSLIRFLEEGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLQELAVVES
                     FPTKIEGRQMIMVLAPKKKQ"
     gene            4925..5122
                     /gene="rpmI"
                     /locus_tag="RHX21_003580"
     CDS             4925..5122
                     /gene="rpmI"
                     /locus_tag="RHX21_003580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006708231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HDV1988711.1"
                     /translation="MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHL
                     RPKAMVSKGDLGLVIACLPYA"
     gene            5175..5531
                     /gene="rplT"
                     /locus_tag="RHX21_003581"
     CDS             5175..5531
                     /gene="rplT"
                     /locus_tag="RHX21_003581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HDV1988712.1"
                     /translation="MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQ
                     YAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFD
                     KVAFTALVEKAKAALA"
     misc_feature    5648..5772
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01859"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Phe leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF01859"
     gene            5654..5698
                     /gene="pheM"
                     /locus_tag="RHX21_003582"
     CDS             5654..5698
                     /gene="pheM"
                     /locus_tag="RHX21_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pheST operon leader peptide PheM"
                     /protein_id="HDV1988713.1"
                     /translation="MNAAIFRFFFYFST"
     gene            5982..6965
                     /gene="pheS"
                     /locus_tag="RHX21_003583"
     CDS             5982..6965
                     /gene="pheS"
                     /locus_tag="RHX21_003583"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004851795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HDV1988714.1"
                     /translation="MSHLAELVASAKAAISQASDVAALDNVRVEYLGKKGHLTLQMTT
                     LRELPPEERPAAGAVINEAKEQVQQALNARKAELESAALNARLAAETIDVSLPGRRIE
                     NGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWF
                     DTTRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNI
                     SFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVH
                     PNVLRNVGIDPEVYSGFAFGMGMERLTMLRYGVTDLRSFFENDLRFLKQFK"
     gene            6980..9367
                     /gene="pheT"
                     /locus_tag="RHX21_003584"
     CDS             6980..9367
                     /gene="pheT"
                     /locus_tag="RHX21_003584"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HDV1988715.1"
                     /translation="MKFSELWLREWVNPAIDSDALANQITMAGLEVDGVEPVAGSFHG
                     VVVGEVVECAQHPNADKLRVTKVNVGGDRLLDIVCGAPNCRQGLRVAVATIGAVLPGD
                     FKIKAAKLRGEPSEGMLCSFSELGISDDHSGIIELPADAPIGTDIREYLKLDDNTIEI
                     SVTPNRADCLGIIGVARDVAVLNQLPLVEPEIVPVGATIDDTLPITVEAPEACPRYLG
                     RVVKGINVKAPTPLWMKEKLRRCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIEGGI
                     VVRMAKEGETLVLLDGTEAKLNADTLVIADHNKALAMGGIFGGEHSGVNDETQNVLLE
                     CAFFSPLSITGRARRHGLHTDASHRYERGVDPALQHKAMERATRLLIDICGGEAGPVI
                     DITNEATLPKRATITLRRSKLDRLIGHHIADEQVTDILRRLGCEVTEGKDEWQAVAPS
                     WRFDMEIEEDLVEEVARVYGYNNIPDEPVQASLIMGTHREADLSLKRVKTLLNDKGYQ
                     EVITYSFVDPKVQQMIHPGVEALLLPSPISVEMSAMRLSLWTGLLATVVYNQNRQQNR
                     VRIFESGLRFVPDTQAPLGIRQDLMLAGVICGNRYEEHWNLAKETVDFYDLKGDLESV
                     LDLTGKLNEVEFRAEANPALHPGQSAAIYLKGERIGFVGVVHPELERKLDLNGRTLVF
                     ELEWNKLADRVVPQAREISRFPANRRDIAVVVAENVPAADILSECKKVGVNQVVGVNL
                     FDVYRGKGVAEGYKSLAISLILQDTSRTLEEEEIAATVAKCVEALKERFQASLRD"
     gene            9372..9671
                     /gene="ihfA"
                     /locus_tag="RHX21_003585"
     CDS             9372..9671
                     /gene="ihfA"
                     /locus_tag="RHX21_003585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit alpha"
                     /protein_id="HDV1988716.1"
                     /translation="MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQV
                     KLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVENASPKDE"
     gene            9772..10752
                     /gene="btuC"
                     /locus_tag="RHX21_003586"
     CDS             9772..10752
                     /gene="btuC"
                     /locus_tag="RHX21_003586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter permease BtuC"
                     /protein_id="HDV1988717.1"
                     /translation="MLTLARQQQRQNIRWLLCLSVLMLLALLLSLCAGEQWISPGDWF
                     SPRGELFVWQIRLPRTLAVLLVGAALAISGAVMQALFENPLAEPGLLGVSNGAGVGLI
                     AAVLLGQGQLPNWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALM
                     TWAIYFSTSVDLRQLMYWMMGGFGGVDWRQSWLMLALIPVLLWICCQSRPMNMLALGE
                     ISARQLGLPLWFWRNVLVAATGWMVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLL
                     PGCALAGASALLLADVVARLALAAAELPIGVVTATLGAPVFIWLLLKAGR"
     gene            10815..11366
                     /gene="btuE"
                     /locus_tag="RHX21_003587"
     CDS             10815..11366
                     /gene="btuE"
                     /locus_tag="RHX21_003587"
                     /EC_number="1.11.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional thioredoxin/glutathione peroxidase"
                     /protein_id="HDV1988718.1"
                     /translation="MQDSILTTVVKDIDGEVTTLEKYAGNVLLIVNVASKCGLTPQYE
                     QLENIQKAWADRGFVVLGFPCNQFLEQEPGSDEEIKTYCTTTWGVTFPMFSKIEVNGE
                     GRHPLYQKLIAAAPTAVAPEESGFYARMVSKGRAPLYPDDILWNFEKFLVGRDGLVIQ
                     RFSPDMTPEDPIVMESIKLALAK"
     gene            11366..12115
                     /gene="btuD"
                     /locus_tag="RHX21_003588"
     CDS             11366..12115
                     /gene="btuD"
                     /locus_tag="RHX21_003588"
                     /EC_number="7.6.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter ATP-binding protein
                     BtuD"
                     /protein_id="HDV1988719.1"
                     /translation="MSIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLA
                     RMAGMTSGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFAMPVWHYLTLHQHDKT
                     RTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANPAGQLLLLDEP
                     MNSLDVAQQSALDKILSALCQQGLAIVMSSHDLNHTLRHAHRAWLLKGGKMLASGRRE
                     EVLTPPNLAQAYGMNFRRLDIEGHRMLISTI"
     gene            12193..12657
                     /locus_tag="RHX21_003589"
     CDS             12193..12657
                     /locus_tag="RHX21_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDV1988720.1"
                     /translation="MRFCLILITALFLAGCSHHKAPPPNARLSDSITVIAGLNDQLQS
                     WHGTPYRYGGMTRRGVDCSGFVVVTMRDRFDLQLPRETKEQASIGTQIDKDELLPGDL
                     VFFKTGSGQNGLHVGIYDTNNQFIHASTSKGVMRSSLDNVYWQKNFWQARRI"
     gene            12904..13617
                     /gene="ydiV"
                     /locus_tag="RHX21_003590"
     CDS             12904..13617
                     /gene="ydiV"
                     /locus_tag="RHX21_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-FlhDC factor"
                     /protein_id="HDV1988721.1"
                     /translation="MKIFLENLYHSDCYFLPIRDNQQLLVGVELITHFSSEDGTVRIP
                     TSRVIAQLTEEQHWQLFSEQLELLKSCQHFFIQHKLFAWLNLTPQVATLLLERDNYAG
                     ELLKYPFIELLINENYPHLNEGKDNRDLLSLSQMYPLVLGNLGAGNSTMKAVFDGLFT
                     RVMLDKSFIQQQITHRSFEPFIRAIQAQISPCCNCIIAGGIDTTEILAQITPFDFHAL
                     QGCLWPAVPINQITTLVQR"
     gene            13680..15116
                     /locus_tag="RHX21_003591"
     CDS             13680..15116
                     /locus_tag="RHX21_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiU family protein"
                     /protein_id="HDV1988722.1"
                     /translation="MTLSFITRWRDELPETYTALSPTPLNNARLIWHNTELANTLSIP
                     SSLFKNAAGVWGGETLLPGMSPLAQVYSGHQFGVWAGQLGDGRGILLGEQLLADGTTM
                     DWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRE
                     TVEPGAMLIRVAPSHLRFGHFEHFYYRREPEKVRQLADFAIRHYWSHLADDEDKYRLW
                     FTDVVARTASLIAQWQTVGFAHGVMNTDNMSLLGLTLDYGPFGFLDDYEPGFICNHSD
                     HQGRYSFDNQPAVALWNLQRLAQTLSPFVAVDALNEALDSYQQVLLTHYGQRMRQKLG
                     FMTEQKEDNALLNELFSLMARERSDYTRTFRMLSLTEQHSAASPLRDEFIDRAAFDDW
                     FARYRRRLQQDEVSDIERQQLMQSVNPALVLRNWLAQRAIEAAEKGDMTELHRLHEAL
                     RNPFSDRDDDYVSRPPDWGKRLEVSCSS"
     gene            complement(15120..>15288)
                     /gene="hemP"
                     /locus_tag="RHX21_003592"
     CDS             complement(15120..>15288)
                     /gene="hemP"
                     /locus_tag="RHX21_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hemin uptake protein HemP"
                     /protein_id="HDV1988723.1"
                     /translation="LTPETDANHKTASPQPIRRISSQTLLGPDGKLIIDHDGQEYLLR
                     KTQAGKLLLTK"
BASE COUNT         3903 a         3455 c         3996 g         3934 t
ORIGIN      
        1 atatgtttct acagttttat aatgattatg atgaatggct atatgaacag ctgacatgtt
       61 ttcatgattt ttagcggcca acagtgtgaa taattgacgt tgactaaaag aatatttttt
      121 tgcaaaagta ctcagtgttg atatataaga taacacgacg tctttattac ccttgctcat
      181 ggcgatgtat aaagcagggg ttccatgtgc tgtcgcgcct tttaataagt ccatgatgtt
      241 gattttgctg agtttatatt taacggcgat cccataaact ttagagagga accgtgtgaa
      301 acacaaaggg tgattatttt ccattgcagc aaataaccct ggttcaccat cacgtgtttt
      361 catggctaaa atatccatca ccattttttt gtttaaaagt tcttgtgcta ttggagtggt
      421 taatgcattc agaaagatat cgattatttc atcgaatcca tacaacatgg agatatagag
      481 tccaggtgtt tcgttagcac ttttagtttg aagtaattta accagattat cttcatgaat
      541 gatatgattg tataccagtg actggatttc ttgcataaat atttttacgt tgtcagtttg
      601 tccgttcatc atagccagaa ataaagcagg tgtaccaacg ctattctgcg cagttattat
      661 ttcaatgatt tctttttcag ggagtatggg caactgtttg aatagtgtaa taagctattg
      721 agtctggcct gtggccatta ttaacaacat tgccgatgga tgtatagggg caaatggcat
      781 tcgtgtcgtg atacccgcta aaatagcaac tggaactccc tcaggtaata gaggaagaat
      841 agcaattgca cagttgcgaa catacctatc agcccaggtc tgagcatcgg gagctgaact
      901 gatgaactta tcaagcgaga gaaagcgccg tgctgtcctg tgggtgcctc tgacggcaac
      961 gttggtatcg ttcgggtcgt aaaaagacac aacataattt aattgtccat acactgactg
     1021 ctttattcgt agccttactg acaaagtatg attgtctata tataaaatcg cggacatatg
     1081 actgacattg tttgccatca ttcgacaaaa gaaaatatct aaagcgaagc caaaatcctt
     1141 actcgcgata acgcgactcc ctgcaggagg atggcgaagt aatgctctga actccgcatc
     1201 ccggactaag gggatatgct gctgtatgga ttcaacggag gagtaatgtt taatcaggtt
     1261 gactttgcct tttccatttc tcaatgaatc aagggcgtat tgcaatgaca gatggcgaca
     1321 aaaaatagcg tcagaaggag attgcaaaaa acatgcacta ccattgagat ttactgttgg
     1381 gtgtatagtt ttttctctat ggattttttt agacagtttc atacaatggt tacgatcttc
     1441 agcagttaac tgttcctgtt caatataatc cagtatgctt cgcaaatggt tagctttaat
     1501 aggcgtggtt tccagtaata aggaaatgaa atctttttta tagtgtaatg taatgagtat
     1561 attttctgca tggatgggtg aagtggcaaa gttaatggta aaaagggcag tggaataaca
     1621 attttgtgat atttttcgac agtttgcgat aaattcctga ataacacagt atgacagcat
     1681 cgaacttaag tcagaggtat caagtagggt gatgagctgg cgcgcaaatt tattaatagg
     1741 ctctgatgaa ggtgttggta tgtcgctatc gatgtgcaat ctatgaggag acttataatg
     1801 agttctgata atgatatcgt tttgactcat aatctattcg ccttatatat atctggaggt
     1861 tttgaggatg atgattaatt attatcgcca gaacgaaatg tgcacgaaaa attgttataa
     1921 gaattgtgtc acttttatca ttgtgatatg accacttcgt cattaatctc atgagcgttt
     1981 aaaatactac cgccaaatca cgcaacgaac tttgctggat tcagtttatg ctgctgtaaa
     2041 tccgctcgca gtaaaccttt cagacgcacc gtgatgttat cagtggttct ttaagcgttt
     2101 tgctggtgta ctcactacaa acgaattgcg aatcgaatca atgtgaaacg gaaaggtaca
     2161 atctcccttt ttttagtgtt aacatcgctc aaccgggtgg aaggtgagag gttaatgtct
     2221 ttcatttgtg tacctgattg cgaaccaatt tagcatttgt tggctagatg gtttcgcaat
     2281 gaactgttaa taaacaaatt tttctttgta tgtgatcttt cgtgtgggtc accactgcaa
     2341 ataaggatat aaaatgcctg ttataactct tcctgatggc agccaacgcc attacgacca
     2401 cgctgtaagc cccatggatg ttgcgctgga cattggtcca ggtctggcga aagcctgtat
     2461 cgcagggcgc gttaatggcg aactggttga tgcttgcgat ctgattgaaa acgacgcaca
     2521 actgtccatc attaccgcca aagacgaaga cggtctggag atcattcgtc actcctgtgc
     2581 gcacctgtta gggcacgcga ttaaacaact ttggccgcat accaaaatgg caatcggccc
     2641 ggttattgac aacggttttt attacgacgt tgatcttgac cgcacgttaa cccaggaaga
     2701 tgtcgaagca ctcgagaagc ggatgcatga gcttgctgag aaaaactacg acgtcattaa
     2761 gaagaaagtc agctggcacg aagcgcgtga aacattcgcc aaccgtgggg agagctacaa
     2821 agtctccatt cttgacgaaa acatcgccca tgatgacaag ccaggtctgt acttccatga
     2881 agaatatgtc gatatgtgcc gcggtccgca cgtaccgaac atgcgtttct gccatcattt
     2941 caaactaatg aaaacggcag gggcttactg gcgtggcgac agcaacaaca aaatgttgca
     3001 acgtatttac ggtacggcgt gggcagacaa aaaagcgctt aacgcttacc tgcagcgcct
     3061 ggaagaagcc gcgaaacgcg accaccgtaa aatcggtaaa cagctcgacc tgtaccatat
     3121 gcaggaagaa gcgccgggta tggtattctg gcacaacgac ggctggacca tcttccgtga
     3181 actggaagtg tttgttcgtt ctaaactgaa agagtaccag tatcaggaag ttaaaggtcc
     3241 gttcatgatg gaccgtgtcc tgtgggaaaa aaccggtcac tgggacaact acaaagatgc
     3301 aatgttcacc acgtcttctg agaaccgtga atactgcatt aagccgatga actgcccggg
     3361 tcacgtacaa attttcaacc aggggctgaa gtcttatcgc gatctgccgc tgcgtatggc
     3421 cgagtttggt agctgccacc gtaatgagcc gtcaggttcg ctgcatggcc tgatgcgcgt
     3481 gcgtggattt acccaggatg acgcgcatat cttctgtact gaagaacaaa ttcgcgatga
     3541 agttaacgga tgtatccgtt tagtctatga tatgtacagc acttttggct tcgagaagat
     3601 cgtcgtcaaa ctctccactc gtcctgaaaa acgtattggc agcgacgaaa tgtgggatcg
     3661 tgctgaggcg gacctggcgg ttgcgctgga agaaaacaac atcccgtttg aatatcaact
     3721 gggtgaaggc gctttctacg gtccgaaaat tgaatttacc ctgtatgact gcctcgatcg
     3781 tgcatggcag tgcggtacag tacagctgga cttctctttg ccttctcgtc tgagcgcttc
     3841 ttatgtaggc gaagacaatg aacgtaaagt accggtaatg attcaccgcg caattttggg
     3901 gtcgatggaa cgtttcatcg gtatcctgac cgaagaattc gctggtttct tcccgacctg
     3961 gcttgcgcca gttcaggttg ttatcatgaa tattaccgat tcacagtctg aatacgttaa
     4021 cgaattgacg caaaaactat caaatgcggg cattcgtgtt aaagcagact tgagaaatga
     4081 gaagattggc tttaaaatcc gcgagcacac tttgcgtcgc gtcccatata tgctggtctg
     4141 tggtgataaa gaggtggaat caggcaaagt tgccgttcgc acccgccgtg gtaaagacct
     4201 gggaagcatg gacgtaaatg aagtgatcga gaagctgcaa caagagattc gcagccgcag
     4261 tcttaaacaa ttggaggaat aaggtattaa aggcggaaaa cgagttcaaa cggcgcgccc
     4321 taaccgtatc aatggcgaaa ttcgcgccca ggaagttcgc ttaacaggtc tggaaggcga
     4381 gcagcttggt attgtgagtc tgagagaagc tctggagaaa gcagaagaag ccggagtaga
     4441 cttagtcgag atcagcccta acgccgagcc gccggtttgt cgtataatgg attacggcaa
     4501 attcctctat gaaaagagca agtcttctaa ggaacagaag aaaaagcaaa aagttatcca
     4561 ggttaaggaa attaaattcc gtcctggtac agatgaaggc gactatcagg taaaactccg
     4621 cagcctgatt cgctttctcg aagagggtga taaagccaaa atcacgctgc gtttccgcgg
     4681 tcgtgagatg gcgcaccagc aaatcggtat ggaagtgctt aatcgcgtga aagacgattt
     4741 gcaagaactg gcagtggtcg aatccttccc aacgaagatc gaaggccgcc agatgatcat
     4801 ggtgctcgct cctaagaaga aacagtaagg ccttcaagta gcactgtctg tggagccttc
     4861 gggcttcaca ggctttgttc gcctttgttt cgtttattaa caatgcgaag tggaagttat
     4921 taaaatgcca aaaattaaga ccgtacgcgg tgctgctaag cgcttcaaaa aaaccggtaa
     4981 aggtggtttt aagcacaagc acgctaacct gcgtcacatt ctgaccaaaa aagcgaccaa
     5041 acgtaaacgt cacctgcgtc cgaaagccat ggtttccaaa ggcgatctgg gcctggtaat
     5101 cgcgtgcctg ccgtacgcat aagccgttaa cgtttttaac tttttaatta gaatatagat
     5161 acaggagagc acatatggct cgcgtaaaac gtggtgttat tgcacgcgca cgtcacaaga
     5221 aaattttgaa acaagctaaa ggctactacg gtgcgcgttc tcgcgtatac cgcgttgcct
     5281 tccaggctgt tatcaaagct ggtcagtatg cttaccgtga ccgtcgtcaa cgtaagcgtc
     5341 agttccgtca actgtggatt gcgcgtatca acgcagcagc acgtcagaac ggtatttctt
     5401 acagcaaatt catcaatggc ctgaaaaaag cctctgttga aatcgaccgt aagatcctgg
     5461 ctgatatcgc agtattcgac aaagtagcgt tcaccgctct ggttgaaaaa gcgaaagcag
     5521 ctctggcata agccagttga aagagggagc tagtctccct cttttcgttt caacgccatc
     5581 aaaacattga cttttatcgc cgtagccttt tcaataaagg tcttttgaag agtaccaaaa
     5641 ggtaacgcaa gcaatgaatg ctgctatttt ccgcttcttt ttttacttta gcacctgaat
     5701 ccaggaggct agcgcgtgag aagagaaacg gaaaacagcg cctgaaagcc tcccagtgga
     5761 ggcttttttt gtatgcgcgt tttgaaaaat aaaaagcctg tctcatcagg tgtaattgtc
     5821 gcagccagtc tggacacggc cagcgcggag aaaccggagc gtatttaagt acgtgagaat
     5881 ttcgagcact gcccgggacc aaaatggcaa gtaaaatagc ctgatgggat aggctctaag
     5941 tccaacgaac cagtgtcacc actgacacaa tgaggaaaac catgtcacat ctcgcagaac
     6001 tggttgccag tgcgaaggcg gccattagcc aggcgtcaga tgttgccgcg ttagataatg
     6061 tgcgcgtcga atatttgggt aaaaaagggc acttaaccct tcagatgacg accctgcgtg
     6121 agctgccgcc agaagagcgt ccggcagctg gtgcggttat caacgaagcg aaagagcagg
     6181 ttcagcaggc gctgaatgcg cgtaaagcgg aactggaaag cgcagcgctg aatgcgcgtc
     6241 tggcggcgga aacgattgat gtctccctgc caggtcgtcg cattgaaaac ggcggtctgc
     6301 atccggttac ccgtaccatc gaccgtatcg aaagtttctt cggtgagctt ggctttaccg
     6361 tggcaaccgg gccggaaatc gaagacgatt atcataactt cgatgctctg aacattcctg
     6421 gtcaccaccc ggcgcgcgct gaccacgaca ctttctggtt tgacactacc cgcctgctgc
     6481 gtacccagac ctctggcgta cagatccgca ccatgaaagc ccagcagcca ccgattcgta
     6541 tcatcgcgcc tggccgcgtt tatcgtaacg actacgacca gactcacacg ccgatgttcc
     6601 atcagatgga aggtctgatt gttgatacca acatcagctt taccaacctg aaaggcactc
     6661 tgcacgattt cctgcgtaac ttctttgagg aagatttgca gattcgcttc cgtccttcct
     6721 acttcccgtt caccgagcct tctgcagaag ttgacgtcat gggtaaaaac ggtaaatggc
     6781 tggaagtgct gggttgcggg atggtgcatc cgaacgtgct gcgtaacgtt ggcatcgacc
     6841 cggaagttta ctctggtttc gccttcggga tggggatgga gcgtctgact atgttgcgtt
     6901 acggcgtcac cgacctgcgt tcattcttcg aaaatgatct gcgtttcctc aaacagttta
     6961 aataaggcag gaatagatta tgaaattcag tgaactgtgg ttacgcgaat gggtgaaccc
     7021 ggcgattgat agcgatgcgc tggcgaatca aatcactatg gcgggcctgg aagttgacgg
     7081 tgtagaaccg gttgccggta gcttccacgg cgtggtcgtt ggtgaagtgg ttgagtgtgc
     7141 gcagcatccg aacgctgaca aactgcgtgt gacaaaagtg aatgttggcg gcgatcgcct
     7201 gctggacatc gtctgcggtg cgccaaactg ccgtcagggc ctgcgtgtgg cggtagctac
     7261 cattggtgct gttctgccgg gtgatttcaa aattaaagcg gcgaaactgc gtggtgaacc
     7321 gtctgaaggg atgctgtgct ccttttctga gctgggaatt tctgacgatc atagcggcat
     7381 tatcgagctg cctgcggatg cgccgattgg caccgacatc cgtgaatacc tgaaacttga
     7441 tgacaacacc atcgaaatca gcgtgacgcc aaaccgtgcc gactgtttag gtatcattgg
     7501 tgttgcgcgt gacgttgccg tgctgaatca gctgccgctg gttgaaccgg aaatcgttcc
     7561 ggttggtgcg accatcgacg acacgctgcc gattacagtc gaagcgccgg aagcctgccc
     7621 gcgttatctt ggccgtgtgg taaaaggcat taacgttaaa gcgccaactc cgctgtggat
     7681 gaaagaaaaa ctgcgtcgtt gcgggatccg ttctatcgat gcagttgttg acgtcaccaa
     7741 ctatgtactg ctcgaactgg gccagccgat gcacgctttc gataaagatc gcattgaagg
     7801 cggcattgtg gtgcggatgg cgaaagaggg cgaaacgttg gtactgcttg atggcactga
     7861 agcgaagctg aatgctgaca ctctggtcat cgccgaccac aacaaggcgc tggcgatggg
     7921 cggcatcttt ggtggcgaac actctggcgt gaatgacgaa acgcaaaacg tcttgctgga
     7981 atgcgctttc ttcagcccgc tgtctatcac cggtcgtgct cgtcgtcatg gcctgcatac
     8041 tgatgcgtct caccgttatg agcgtggcgt tgatccggca ctgcagcaca aagcgatgga
     8101 acgtgcgacc cgtctgctga tcgacatctg cggtggtgag gctggtccgg taattgatat
     8161 caccaacgaa gcaacgctgc cgaagcgtgc aaccatcact ttacgtcgta gcaaactgga
     8221 tcgcctgatc ggccatcata ttgcggatga gcaggtaact gacattctgc gtcgtctcgg
     8281 ctgcgaagtg accgaaggca aagacgagtg gcaggcagtt gcgccgagct ggcgtttcga
     8341 tatggagatt gaagaagatc tggtcgaaga agtcgcgcgt gtttacggct acaacaacat
     8401 cccggatgag ccggtacagg caagcctgat tatgggtact caccgtgaag ctgacctgtc
     8461 gctcaagcgc gtgaaaacgc tgctcaacga caaaggctat caggaagtga tcacctacag
     8521 cttcgttgat ccgaaagtgc agcagatgat ccatccaggc gttgaagcct tactgctgcc
     8581 aagcccgatc tctgttgaaa tgtcagcaat gcgtctttct ctgtggaccg gcctgctggc
     8641 aaccgtggtg tacaaccaga accgtcagca gaaccgtgtg cgcattttcg aaagcggtct
     8701 gcgtttcgta ccagatactc aggcaccgtt gggcattcgt caggatctga tgttagccgg
     8761 tgtgatttgc ggtaaccgtt acgaagagca ctggaacctg gcaaaagaga ccgttgattt
     8821 ctatgatttg aaaggcgatc ttgaatccgt tctcgacctg accggtaaac tgaatgaggt
     8881 tgagttccgt gcagaagcga atccggcact gcatccgggg caatccgcag cgatttatct
     8941 gaaaggtgaa cgtattggtt ttgttggggt tgttcatcct gaactggaac gtaaactgga
     9001 tcttaacggt cgcactctgg tgttcgaact ggagtggaac aagctcgcag accgcgtggt
     9061 gcctcaggcg cgcgagattt ctcgcttccc ggcgaaccgt cgtgacatcg cggtggtggt
     9121 cgcagaaaac gttcccgcag cggatatttt atccgaatgt aagaaagttg gcgtaaatca
     9181 ggtagttggc gtaaacttat ttgacgtgta ccgcggtaag ggtgttgcgg aggggtataa
     9241 gagcctcgcc ataagcctga tcctgcaaga taccagccgt acactcgaag aagaggagat
     9301 tgccgctacc gtcgccaaat gtgtagaggc attaaaagag cgattccagg catcattgag
     9361 ggattgaacc tatggcgctt acaaaagctg aaatgtcaga atatctgttt gataagcttg
     9421 ggcttagcaa gcgggatgcc aaagaactgg ttgaactgtt tttcgaagag atccgtcgcg
     9481 ctctggaaaa cggcgaacag gtgaaactct ctggttttgg taacttcgat ctgcgtgata
     9541 agaatcaacg cccgggacgt aacccgaaaa cgggcgagga tattcccatt acagcacggc
     9601 gcgtggtgac cttcagaccc gggcagaagt taaaaagccg ggtcgaaaac gcttcgccca
     9661 aagacgagta atctgatcta actaaaaagg ccgctctgcg gccttttttc ttttcactgt
     9721 cgaagagtca ccgtaaaatc aacgccatga cacttcagca gaacggatac catgctgaca
     9781 cttgcccgcc aacaacagcg acaaaatatt cgctggttat tatgcctgtc agttttgatg
     9841 ctgctggcgc ttctcttaag cctttgcgcc ggtgaacaat ggatctcgcc aggtgactgg
     9901 ttttctcctc gtggcgaact gttcgtctgg cagattcgcc tgccacgtac gctggctgta
     9961 ttgctggttg gtgcggcgct ggctatatcc ggcgcagtaa tgcaggcgtt gtttgaaaat
    10021 cctctggcag aacctggact acttggcgtc tctaacggcg caggcgtagg gcttatcgcc
    10081 gcggtattgc ttgggcaagg gcaactccca aactgggcac tagggctgtg tgcgattgct
    10141 ggcgcgctta tcatcacttt aatactctta cgtttcgccc gtcgtcatct ttcgaccagt
    10201 cggttattgc tggctggcgt tgcattaggg attatctgta gcgcactaat gacgtgggct
    10261 atctactttt ccacctctgt tgatttacgt cagctgatgt actggatgat gggcggtttt
    10321 ggcggcgtag actggcggca aagctggctg atgctggcat tgatccccgt gttgttgtgg
    10381 atctgttgtc agtccaggcc gatgaatatg ttagcacttg gcgagatctc ggcgcggcaa
    10441 ctgggtttac ccctgtggtt ctggcgcaat gtgctggtgg cagcgaccgg ctggatggtt
    10501 ggcgtcagtg tggcgctggc gggtgctatc ggctttattg gtctggtgat cccacatatt
    10561 cttcggttgt gtggtttaac cgatcatcgc gtattacttc ccggctgcgc gctggcaggg
    10621 gcgagcgcat tgctgctggc cgatgttgta gcgcgcttgg cattagctgc cgcagagctg
    10681 cctattggcg tggtcaccgc aacgttgggt gcgccggtgt ttatctggtt attgttaaaa
    10741 gcaggacgtt agccgcaaaa agacggtcta tgattaaaag ctaagatttt tactgaccac
    10801 acccaggaga aacgatgcaa gattccattc tgacgaccgt agtgaaagat atcgacggtg
    10861 aagtgaccac gctggagaag tacgccggta atgtgctgtt gattgtcaat gtcgcctcaa
    10921 agtgtggctt aacgccgcaa tatgagcagt tggagaatat tcagaaagcc tgggccgatc
    10981 gaggttttgt ggtgctggga ttcccgtgca accagtttct ggaacaagaa ccgggcagcg
    11041 atgaagagat taaaacttac tgtaccacca catggggggt gacgttcccg atgttcagta
    11101 agattgaagt taatggcgaa ggacgccatc cgctgtatca aaaattgatt gccgcagcgc
    11161 cgaccgcagt cgcgccggaa gagagcggat tctatgcccg tatggtcagc aaaggtcgtg
    11221 caccgctgta ccctgatgat attttatgga attttgagaa atttttagtt ggcagggacg
    11281 gattggtcat ccagcgtttt tccccggata tgacgccgga agaccccatt gtgatggaaa
    11341 gcattaaact ggcgttggca aaataatgtc tattgtgatg cagttacagg atgttgcgga
    11401 atctacccgc ctggggccac tttctggcga ggttcgggct ggggagatcc tgcatctggt
    11461 ggggccgaat ggcgcgggta agagtacctt gcttgcacga atggccggaa tgaccagcgg
    11521 taagggaagc attcagttcg cggggcaacc cctggaagca tggtccgcaa caaaactcgc
    11581 gctgcatcgc gcctatcttt cacaacagca gacgccgccg tttgcaatgc cggtctggca
    11641 ctacctgaca ctgcatcagc acgataaaac gcgtaccgaa ctactgaatg atgtcgcagg
    11701 ggcgctggct cttgatgaca aactcggacg tagcaccaat caactttccg gcggtgaatg
    11761 gcaacgcgta cgtcttgctg cggtggtgct gcaaatcaca ccacaagcca atcccgcagg
    11821 tcaattgctg cttcttgatg agccgatgaa cagtcttgat gttgcgcaac aaagtgcgtt
    11881 agacaaaatt ctgagcgctc tgtgtcagca aggactggcg attgtgatga gcagtcacga
    11941 tctcaaccac acattgcgtc atgcgcatcg ggcgtggttg ctaaaaggtg gaaaaatgct
    12001 ggccagtgga cgcagagaag aggtgctcac gccgccaaat ctggcgcagg cctatgggat
    12061 gaattttcgc cgtctggata tcgaaggtca cagaatgctg atttcgacca tctgatttca
    12121 ttagtatctt gaaaatcggg taattacgac gctaaattaa tgcaagaata aaaaacagag
    12181 gaaccgtacg gaatgcgttt ctgccttatt ttgatcacag cactgtttct ggccgggtgt
    12241 agccaccata aagcaccgcc gccaaatgcc agactttctg attcgattac cgttattgcc
    12301 ggtttgaacg accagctaca aagctggcat ggcacgccgt atcgttatgg tggcatgacg
    12361 cggcgcggtg tggactgttc gggatttgtg gttgtaacga tgcgcgatcg tttcgatttg
    12421 caactgcccc gagaaaccaa agaacaagcc tctatcggca cgcaaattga taaagacgag
    12481 ttgctgcctg gtgacctggt ctttttcaaa acggggtccg gacaaaatgg tttgcatgta
    12541 ggtatttacg ataccaacaa ccaatttatc cacgcctcta ccagcaaggg agtgatgcgt
    12601 tcctcacttg ataatgtcta ttggcagaaa aatttctggc aggcgagacg aatctagtat
    12661 gtcgaaaaat ggacggcgat gatacatcgc cgtccattta ctcctgaata cagtagtatt
    12721 ttgcagacaa aaattccgta aatggattat tcgtttataa tcaggataat ctaaaaaaag
    12781 gacccctgaa aaagtggtta acatggaaca aatgaaagtt actccttctg taattgttat
    12841 gtcttatggc ctcatccctt ttagccggat actgaaaaac atccttcgag agggacggtt
    12901 accatgaaga tttttttgga gaatctttat cattctgatt gctatttcct gccgataaga
    12961 gataaccagc aactccttgt cggcgttgag ttaattaccc atttctccag tgaagatggc
    13021 acggtgcgta tcccgacgag tcgggttata gcgcaactta ccgaggagca acattggcaa
    13081 ttattttcag agcagttgga attactaaaa tcatgccaac atttttttat tcaacataaa
    13141 ctctttgcct ggcttaattt aacgccacaa gtggctacat tattattaga gagggataat
    13201 tacgcaggcg aactattaaa atatccgttt attgaactgt tgattaatga gaattacccg
    13261 catctcaatg aaggaaaaga taatcgcgat cttttatcct tatcgcaaat gtatcccctt
    13321 gtgttaggca atttgggagc aggtaatagc acaatgaaag cggtttttga tggtcttttc
    13381 acccgcgtca tgctggataa aagttttatt cagcaacaaa tcacgcatcg ctccttcgaa
    13441 ccgtttattc gtgcgatcca ggcgcaaatt tccccttgtt gcaattgcat catcgcgggg
    13501 ggcattgata cgacagaaat attggcacag attaccccct tcgatttcca tgctctccag
    13561 ggatgcctgt ggcctgccgt tcctataaat cagataacga cgttggttca gcgataaccc
    13621 tcctgtttgc tggtgtttaa gacgagagta accgtctaca ctatcaaaca ggaggatcta
    13681 tgaccctgtc ttttattacc cgctggcgcg atgaattgcc agaaacctat acagcacttt
    13741 cccctacgcc tttaaataat gcccggctga tttggcataa taccgaactc gctaacacgc
    13801 tgagtattcc atcgtcgctg tttaaaaatg ctgcaggtgt ctggggcggc gaaaccctac
    13861 tgcctggtat gtcaccactg gcgcaggttt acagtggtca tcagttcggc gtctgggcgg
    13921 gccaactggg tgatgggcgc ggcattttac ttggcgaaca actgcttgct gatggcacta
    13981 caatggactg gcatctgaaa ggtgctggcc tgacgcctta ttcgcgaatg ggtgatggac
    14041 gggcggtttt acgttcgacg atacgagaaa gtctcgccag tgaggcgatg cattatctgg
    14101 gcattccgac gacccgcgcg ttaagtatcg tcaccagcga ttcgccagtg tatcgggaaa
    14161 cggtggagcc aggcgcgatg ctgatacgtg tggcaccaag tcatctgcgc tttggtcatt
    14221 tcgaacattt ttactatcgc cgcgagccgg aaaaggttcg tcagttagct gactttgcca
    14281 ttcgtcatta ctggtcacat cttgcagatg atgaggacaa ataccgtctc tggtttaccg
    14341 atgttgtcgc acgtaccgca tcgttaattg cccaatggca gacggtcggc tttgctcatg
    14401 gggtgatgaa taccgacaac atgtcgctgc tggggctgac gcttgattac gggccgtttg
    14461 gttttcttga tgattacgaa cccggtttta tttgtaatca ctcggatcat caagggcgtt
    14521 atagctttga taatcaacct gctgtcgcgt tgtggaattt acagcgtctg gcgcagacat
    14581 tgtcaccatt tgttgccgta gatgccctga atgaggccct ggacagctat cagcaggttt
    14641 tgttgacgca ttatggacaa cggatgcggc agaaactggg cttcatgacg gagcaaaaag
    14701 aggataacgc gctactgaat gaattattca gtctgatggc gcgagagcgc agcgattata
    14761 cccgcacatt ccgcatgctg agtctgaccg agcagcacag cgcggcgtca ccgctacgtg
    14821 atgagtttat tgatcgtgcg gcatttgatg actggtttgc ccgttatcgg aggcgtttgc
    14881 aacaagacga ggttagcgat attgagcgtc agcaactgat gcaaagcgtt aacccagctc
    14941 tggtgttgcg caactggttg gcgcaacggg cgattgaagc ggcagaaaag ggtgatatga
    15001 cggaattgca ccgcctgcat gaggcgttgc gaaatccttt cagcgacaga gatgatgact
    15061 atgtcagtcg tccacctgac tggggtaaac ggctggaagt cagctgctcg agttaaaggc
    15121 tacttagtta acagcagctt gccagcctga gttttacgga gcagatattc ttgcccgtca
    15181 tgatcgataa tcagtttgcc atccggacct aacagtgtct ggctggaaat tcgccgaata
    15241 ggctgcgggg aagcggtctt gtgattggca tccgtttcag gcgtgagt
//
LOCUS       DAPGUL010000109        14979 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.111, whole genome shotgun sequence.
ACCESSION   DAPGUL010000109 DAPGUL010000000
VERSION     DAPGUL010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14979)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14979)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14979
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.111"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(23..481)
                     /locus_tag="RHX21_003593"
     CDS             complement(23..481)
                     /locus_tag="RHX21_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414921.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HDV1988724.1"
                     /translation="MTIWVDADACPNVIKEILYRAAERMQMPLVLVANQSLRVPPSRF
                     IRTLRVAAGFDVADNEIVRQCEAGDLVITADIPLAAEAIEKGAAALNPRGERYTPATI
                     RERLTMRDFMDTLRASGIQTGGPDSLSQRDRQAFAAELEKWWLEVQRSRG"
     gene            601..1410
                     /gene="proC"
                     /locus_tag="RHX21_003594"
     CDS             601..1410
                     /gene="proC"
                     /locus_tag="RHX21_003594"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDV1988725.1"
                     /translation="MEKKIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVAA
                     LHDQFGINAAESAQEVAQIADIIFAAVKPGIMIKVLSEITSSLNKDSLVVSIAAGVTL
                     DQLARALGHDRKIIRAMPNTPALVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVI
                     AEPMIHPVVGVSGSSPAYVFMFIEAMADAAVLGGMPRAQAYKFAAQAVMGSAKMVLET
                     GEHPGALKDMVCSPGGTTIEAVRVLEEKGFRAAVIEAMTKCMEKSEKLSKS"
     gene            complement(1427..2542)
                     /gene="adrA"
                     /locus_tag="RHX21_003595"
                     /gene_synonym="dgcC"
     CDS             complement(1427..2542)
                     /gene="adrA"
                     /locus_tag="RHX21_003595"
                     /gene_synonym="dgcC"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase AdrA"
                     /protein_id="HDV1988726.1"
                     /translation="MFPKIMNDENFFKKAAAHGEEPPLTPQNEHQRSGLRFARRVRLP
                     RAVGLAGMFLPIASTLVSHPPPGWWWLVLVGWAFVWPHLAWQIASRAVDPLSREIYNL
                     KTDAVLAGMWVGVMGVNVLPSTAMLMIMCLNLMGAGGPRLFVAGLVLMVVSCLVTLEL
                     TGITVSFNSAPLEWWLSLPIIVVYPLLFGWVSYQTATKLAEHKRRLQVMSTRDGMTGV
                     YNRRHWETMLRNEFDNCRRHNRDATLLIIDIDHFKSINDTWGHDVGDEAIVALTRQLQ
                     ITLRGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVREGLNTLRLPNTPQVTLRISVG
                     VAPLNPQMSHYREWLKSADLALYKAKKAGRNRTEVAA"
     gene            complement(2644..2964)
                     /gene="psiF"
                     /locus_tag="RHX21_003596"
     CDS             complement(2644..2964)
                     /gene="psiF"
                     /locus_tag="RHX21_003596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414918.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PsiF"
                     /protein_id="HDV1988727.1"
                     /translation="MKITLLVTLLFGLVFLTTVGAAERTLTPQQQRMTSCNQQATAQA
                     LKGDARKTYMSDCLKNSKSAPGEKSLTPQQQKMRECNNQATQQSLKGDDRNKFMSACL
                     KKAA"
     gene            complement(3083..4498)
                     /gene="phoA"
                     /locus_tag="RHX21_003597"
     CDS             complement(3083..4498)
                     /gene="phoA"
                     /locus_tag="RHX21_003597"
                     /EC_number="3.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414917.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase"
                     /protein_id="HDV1988728.1"
                     /translation="MKQSTIALALLSLLFTPVTKARTPEMPVLENRAAQGDITAPGGA
                     RRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPL
                     TGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKA
                     AGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLL
                     NARADVTLGGGAKTFAETATAGEWQGKTLREQAQARGYQLVSDAASLNSVTEANQQKP
                     LLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSK
                     NEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKDGNTLVIVTADH
                     AHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAAN
                     VVGLTDQTDLFYTMKAALGLK"
     gene            complement(4599..4859)
                     /gene="iraP"
                     /locus_tag="RHX21_003598"
     CDS             complement(4599..4859)
                     /gene="iraP"
                     /locus_tag="RHX21_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraP"
                     /protein_id="HDV1988729.1"
                     /translation="MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQND
                     QQRLIDQVEGALYEVKPDASIPDDDTELLRDYVKKLLKHPRQ"
     gene            complement(5041..5244)
                     /locus_tag="RHX21_003599"
     CDS             complement(5041..5244)
                     /locus_tag="RHX21_003599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988730.1"
                     /translation="MLQSSADEACNVLVKKVRYLKDVRKITKMMNGKLIYSWLKWPCG
                     EFFSLNYKLTKRIYFITFIYNKG"
     gene            5322..6416
                     /gene="ddlA"
                     /locus_tag="RHX21_003600"
     CDS             5322..6416
                     /gene="ddlA"
                     /locus_tag="RHX21_003600"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDV1988731.1"
                     /translation="MEKLRVGIVFGGKSAEHEVSLQSAKNIVDAIDKSRFDVVLLGID
                     KQGQWHVSDASNYLLNADDPAHIALRPSATSLAQVPGKHEHQLIDAQNGQPLLTVDVI
                     FPIVHGTLGEDGSLQGMLRVANLPFVGSDVLASAACMDKDVTKRLLRDAGLNIAPFIT
                     LTRANRHNISFAEVESKLGLPLFVKPANQGSSVGVSKVTSEEQYAIAVDLAFEFDHKV
                     IVEQGIKGREIECAVLGNDNPQASTCGEIVLTSDFYAYDTKYIDEDGAKVVVPAAIAP
                     EINDKIRAIAVQAYQTLGCAGMARVDVFLTPENEVVINEINTLPGFTNISMYPKLWQA
                     SGLGYTDLITRLIELALERHAADNALKTTM"
     gene            complement(6440..6652)
                     /locus_tag="RHX21_003601"
     CDS             complement(6440..6652)
                     /locus_tag="RHX21_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414914.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2754 domain-containing protein"
                     /protein_id="HDV1988732.1"
                     /translation="MNLPVKIRRDWHYYAFAIGLIFILNGVVGLLGFEAKGWQTYAVG
                     LVTWVISFWLAGLIIRRRDEETENAQ"
     gene            6912..7220
                     /locus_tag="RHX21_003602"
     CDS             6912..7220
                     /locus_tag="RHX21_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiY family protein"
                     /protein_id="HDV1988733.1"
                     /translation="MADFTLSKSLFSGKYRNASSTPGNIAYALFVLFCFWAGAQLLNL
                     LVHAPGVYERLMQVQETGRPRVEIGLGVGTIFGLIPFLVGCLIFAVVALWLHWRHRRQ
                     "
     gene            complement(7279..8373)
                     /gene="yaiW"
                     /locus_tag="RHX21_003603"
     CDS             complement(7279..8373)
                     /gene="yaiW"
                     /locus_tag="RHX21_003603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-exposed outer membrane lipoprotein YaiW"
                     /protein_id="HDV1988734.1"
                     /translation="MSRVNHLSSLSLLAVLVLAGCSSQAPQPLKKGEKAIDVASVVRQ
                     KMPASVKDRDAWAKDLATTFESQGLAPTLENVCSVLAVAQQESNYQADPAVPGLSKIA
                     WQEIDRRAERMHIPAFLVHTALKIKSPNGKSYSERLDSVRTEKQLSAIFDDLISMVPM
                     GQTLFGSLNPVRTGGPMQVSIAFAEQHTKGYPWKMDGTVRQEVFSRRGGLWFGTYHLL
                     NYPASYSAPIYRFADFNAGWYASRNAAFQNAVSKASSVKLALDGDLIRYDSKEPGKTE
                     LATRKLAAKLGMSDSEIRRQLEKGDSFSFEETALYKKVYQLAEAKTGKSLPREMLPGI
                     QLESPKITRNLTTAWFAKRVDERRARCMKQ"
     gene            complement(8386..9606)
                     /gene="sbmA"
                     /locus_tag="RHX21_003604"
     CDS             complement(8386..9606)
                     /gene="sbmA"
                     /locus_tag="RHX21_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706191.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide antibiotic transporter SbmA"
                     /protein_id="HDV1988735.1"
                     /translation="MFKSFFPKPGAFFLSAFVWALIAVIFWQAGGGDWVARITGASGQ
                     IPISAARFWSLDFLIFYAYYIVCVGLFAFFWFIYSPHRWQYWSILGTALIIFVTWFLV
                     EVGVAVNAWYAPFYDLIQTALSSPHKVTIEQFYREVGVFLGIALIAVVISVLNNFFVS
                     HYVFRWRTAMNEYYMANWQQLRHIEGAAQRVQEDTMRFASTLENMGVSFINAIMTLIA
                     FLPVLVTLSAHVPELPIIGHIPYGLVIAAIVWSLMGTGLLAVVGIKLPGLEFKNQRVE
                     AAYRKELVYGEDDATRATPPTVRELFSAVRKNYFRLYFHYMYFNIARILYLQVDNVFG
                     LFLLFPSIVAGTITLGLMTQITNVFGQVRGAFQYLINSWTTLVELMSIYKRLRSFEHE
                     LDGDKIQEVTHTLS"
     gene            9958..11115
                     /gene="ampH"
                     /locus_tag="RHX21_003605"
     CDS             9958..11115
                     /gene="ampH"
                     /locus_tag="RHX21_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine-
                     carboxypeptidase/endopeptidase AmpH"
                     /protein_id="HDV1988736.1"
                     /translation="MKRSLLFSAVLCAASLTSVHAAQPITEPEFASDIVDRYADHIFY
                     GSGATGMALVVIDGNQRVFRSYGETRPGNNVRPQLDSVVRIASLTKLMTSEMLVKLLD
                     QGTVKLNDPLSKYAPPGARVPTYNGTPITLVNLATHTSALPREQPGGAAHRPVFVWPT
                     REQRWKYLSTAKLKAAPGSQAAYSNLAFDLLADALANASGKPYTQLFEEQITRPLGMK
                     DTTYTPSPDQCRRLMVAERGASPCNNTLAAIGSGGVYSTPGDMMRWMQQYLSSDFYQR
                     SNQADRMQTLIYQRAQFTKVIGMDVPGKADALGLGWVYMAPKEGRPGIIQKTGGGGGF
                     ITYMAMIPQKNIGAFVVVTRSPLTRFKNMSDGINDLVTELSGNKPLVIPAS"
     gene            complement(11116..11739)
                     /gene="iprA"
                     /locus_tag="RHX21_003606"
     CDS             complement(11116..11739)
                     /gene="iprA"
                     /locus_tag="RHX21_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414909.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogen peroxide resistance inhibitor IprA"
                     /protein_id="HDV1988737.1"
                     /translation="MLSVVKPLQEFGKLDKCLSRYGTRFEFNNEKQVIFSSDVNSENT
                     FVILEGVISLRREENVLIGITQAPYIMGLADGLMKNDIPYKLISEGNCTGYHLPAKQT
                     ITLIEQNQLWRDAFYWLAWQNRILELRDVQLIGHNSYEQIRATLLSMIDWNEELRSRI
                     GVMNYIHQRTRISRSVVAEVLAALRKGGYIEMNKGKLVAINRLPSEY"
     gene            complement(11827..14733)
                     /locus_tag="RHX21_003607"
     CDS             complement(11827..14733)
                     /locus_tag="RHX21_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HDV1988738.1"
                     /translation="MHSWKKKLVVSQLALACTLAITSQANAANYDTWTYIDNPVTALD
                     WDHMDKAGTVDGNYVNYSGFVYYNNTNGDFDQSFNGDTVNGTISTYYLNHDYADSTAN
                     QLDISNSVIHGSITSMLPGGYYDRFDADGNNLGGYDFYTDAVVDTHWRDGDVFTLNIA
                     NTTIDDDYEALYFTDSYKDGDVTKHTNETFDTSEGVAVNLDVESNINISNNSRVAGIA
                     LSQGNTYNETYTTESHTWDNNISVKDSTVTSGSNYILDSNTYGKTGHFGNSDEPSDYA
                     GPGDVAMSFTASGSDYAMKNNVFLSNSTLMGDVAFTSTWNSNFDPNGHDSNGDGVKDT
                     NGGWTDDSLNVDELNLTLDNGSKWVGQAIYNVAETSAMYDVATNSLTPDATYENNDWK
                     RVVDDKVFQSGVFNVALNNGSEWDTTGRSIVDTLTVNNGSQVNVSESKLTSDTIDLTN
                     GSSLNIGEDGYVDTDHLTINSYSTVALTESTGWGADYNLYANTITVTNGGVLDVNVDQ
                     FDTEAFRTDKLELTSGNIADHNGNVVSGVFDIHSSDYVLNADLVNDRTWDTSKSNYGY
                     GIVAMNSDGHLTINGNGDVDNGTELDNSSVDNVVAATGNYKVRIDNATGAGAIADYKD
                     KEIIYVNDVNTNATFSAANKADLGAYTYQAEQRGNTVVLQQMELTDYANMALSIPSAN
                     TNIWNLEQDTVGTRLTNSRHGLADNGGAWVSYFGGNFNGDNGTINYDQDVNGIMVGVD
                     TKIDGNNAKWIVGAAAGFAKGDMNDRSGQVDQDSQTAYIYSSAHFANNVFVDGSLSYS
                     HFNNDLSATMSNGTYVDGSTNSDAWGFGLKAGYDFKLGDAGYVTPYGSVSGLFQSGDD
                     YQLSNDMKVDGQSYDSMRYELGVDAGYTFTYSEDQALTPYFKLAYVYDDSNNDNDVNG
                     DSIDNGTEGSAVRVGLGTQFSFTKNFSAYTDANYLGGGDVDQDWSANVGVKYTW"
BASE COUNT         3811 a         3794 c         3532 g         3842 t
ORIGIN      
        1 aagtgtaaat aataaattac atttagccac gactacgttg cacttccagc caccacttct
       61 ccagctccgc ggcaaaggcc tggcggtcac gttgtgaaag gctatctggt ccgccggtct
      121 ggatcccact ggcacgtaag gtatccataa aatcgcgcat cgtcaggcgc tcacgaatgg
      181 tcgctggcgt gtaacgttcg ccgcgcggat taagcgccgc tgcgcctttc tcgatggctt
      241 cagcagccaa aggtatatct gcggtgatca ccaaatcgcc cgcttcacac tgccggacaa
      301 tttcgttatc ggcaacgtcg aaacctgccg cgacgcgcag cgtacgaata aatcgcgatg
      361 gcggcacgcg taaactctgg tttgctacca gtaccagcgg catctgcata cgttccgccg
      421 cgcgatacaa aatctcttta attacattgg gacacgcgtc ggcatccacc caaattgtca
      481 taaagtcatc ctttgttggg taattctcta ttgtgtcgcg cttttgcctt ccggcatagt
      541 tctgtttatg cttctgccag cgattatcaa aacaatgaat ttcacggcag gagtgaggca
      601 atggaaaaga aaatcggttt tattggctgc ggcaatatgg gaaaagccat tctcggcggt
      661 ctgattgcca gcggtcaggt gcttccaggg caaatctggg tatacacccc ctccccggat
      721 aaagtcgccg ccctgcatga ccagttcggc atcaacgccg cagaatcggc gcaagaagtg
      781 gcgcaaatcg ccgacatcat ttttgctgcc gttaaacctg gcatcatgat taaagtgctt
      841 agcgaaatca cctccagcct gaataaagac tctctggtcg tttctattgc tgcaggtgtc
      901 acgctcgacc aacttgcccg cgcgctgggc catgaccgaa aaattatccg cgccatgccg
      961 aacactcccg cgctggttaa tgccgggatg acctccgtaa cgccaaacgc gctggtaacc
     1021 ccagaagata ccgctgatgt gctgaatatt ttccgctgct ttggcgaagc ggaagtaatt
     1081 gctgagccga tgatccaccc ggtggtcggt gtgagcggtt cttcgccagc ctacgtattt
     1141 atgtttatcg aagcgatggc cgacgccgcc gtgctgggcg ggatgccacg cgcccaggcg
     1201 tataaatttg ccgctcaggc ggtaatgggt tccgcaaaaa tggtgctgga aacgggagaa
     1261 catccggggg cactgaaaga tatggtctgc tcaccgggag gcaccaccat tgaagcggta
     1321 cgcgtactgg aagagaaagg cttccgtgcc gcagtgatcg aagcgatgac gaagtgtatg
     1381 gaaaaatcag aaaaactcag caaatcctga tgactttcgc cggacgtcag gccgccactt
     1441 cggtgcggtt acgtccggct ttctttgctt tgtaaagcgc caaatctgcc gatttcaacc
     1501 actcacgata gtgactcatt tgtgggttca gcggcgcaac ccccacacta atccgtaaag
     1561 ttacctgtgg cgtattcggc aagcgtaacg tgtttagccc ttcacgcacc cgtaacatgg
     1621 cggtaatggc gctctcagct ggcgtaccgg acatgattac tgcaaactca tcgccgccaa
     1681 accgaccaat cacatcgcta ccgcgcaggg taatttgtaa ctgtcgggta agcgccacaa
     1741 tcgcttcatc gcccacatca tgaccccagg tatcgttgat gctcttgaaa tggtcgatat
     1801 cgataatcag taacgttgca tcgcgattat gccgccgaca gttatcaaat tcattgcgta
     1861 acatagtttc ccaatgacgt cggttataca cgcccgtcat gccgtcgcgg gtactcatga
     1921 cctgcaacct gcgtttatgt tccgccagtt tggttgccgt ctggtagctg acccagccaa
     1981 acagcagagg ataaacgaca ataatgggaa gggagagcca ccattccagc ggcgcactat
     2041 tgaacgacac ggtaatgccc gtaagctcga gggtgacaag gcaggaaacc accatcaaca
     2101 ccagacccgc gacaaacaga cgggggccgc ctgcccccat caaattcaga cacataatca
     2161 tcaacatagc ggtggaaggc agcacgttta cgcccattac gcctacccac attcccgcta
     2221 atactgcatc ggtttttaag ttgtaaattt cccggctaag cggatcgacg gccctgctcg
     2281 ctatctgcca ggctaaatgc ggccagacga acgcccagcc gaccaacacc agccaccacc
     2341 agcccggcgg cgggtgcgaa accagcgttg aagcaatcgg taagaacatg ccagccaggc
     2401 caaccgcacg gggtagtctg acgcgacggg cgaagcgcag cccggaccgc tgatgttcgt
     2461 tttgaggagt taaaggaggt tcctccccat gcgccgccgc ttttttgaaa aagttttcat
     2521 cattcattat ttttgggaac attcagaaac aattttccca aattatagag acggggctaa
     2581 aggcagaagt atgaaatttc gggtgagcca ctttcgtagc tcacccgtta gcactatcag
     2641 gtatcaggcg gctttcttga ggcaggcact cataaactta ttacgatcat cacctttcag
     2701 agattgttgc gttgcttgat tattacattc gcgcatcttt tgctgctgtg gcgtcaaact
     2761 tttttcacca ggcgcagact tgctgttctt caggcaatca ctcatgtagg tcttacgagc
     2821 atcccctttc aacgcctgcg ccgtcgcctg ctgattacag gatgtcatac gctgttgttg
     2881 tggggttaag gttctctcgg cagcgccgac ggtggttaaa aaaaccagac caaaaagcaa
     2941 ggtaaccagt aatgttattt tcatagcacc atccctcttc atgttttaac catgagcgta
     3001 tgcgcccgtg atctgccatt aagtctggtt gctaacagca aaaaaaccac ccggcagcga
     3061 aaattcactg ccgggcgcgg ttttatttca gccccagggc ggctttcatg gtgtagaaga
     3121 gatcggtctg gtcggtcagt ccaacaacat tggcggcatg cgggccatac gccgcaatac
     3181 gcaactgact gccggtatgt tcttgtgaat cctcttcgga gttcccgtag ctcatcacca
     3241 tcactgcgcc atctttggta tttagcgcct gggtgaggcc cggagctttg gtatccggcg
     3301 cgacaatctg gctggcgtgg gcgtgatcag cggtgactat gaccagcgta ttgccatcct
     3361 ttttagcgaa ttccagcgcc cgttgtacgg cttcatcgag atcgaccgtc tcgccaattt
     3421 gcccacaagg attcgcagcg tgatcctgtt tatcgattga cgcaccttca acttgcagga
     3481 aaaatccttt ctcattttta ctcaacaatt caatggcttt gtcggtcatc tgcgccaggg
     3541 ttggtacact gtcattacgt tgcggattag gcgtacaggt gactgcgggc ttatcgatat
     3601 tgccgtggta cgttgctttc ggtcctagcc agcgcactgg catattgccg tcagcaaaca
     3661 gtccaagcag aggtttttgc tgattcgctt ccgtcaccga attcagtgag gcagcatcgc
     3721 tgaccaactg ataaccacgc gcctgtgcct gttcacgcag cgtttttccc tgccattcac
     3781 cggcggttgc cgtttcagca aaggtttttg cgccaccgcc aagcgtaacg tcggcacgag
     3841 cgttaagcag ctgttcggta atcgatcctt ttccgccttt ttccagagcg ttacccggac
     3901 atttttcact ggtcgcgctc ggaccgtagc atttgcgcga ggtcacatgc gccaccagcg
     3961 cagcgggcgt ggcatcctgc aactctgcgg tagaaacgtt accggtcgcc agacctgcgg
     4021 cttttgccat ttccagaatc gttgggtgat ctttttcgtg aatatcgacg cccagcgcgc
     4081 cgttataggt tttgacaccg gttgaccagg cggttgctga tgcagccgag tcggtgacgt
     4141 agtccggttt gccggttttt ttattcagcg catagtgagt gtattgcccg gtaagcggta
     4201 aggcatcgat acctttaaaa aagccgcccg caccttcggc ataattacgt gcggcagtaa
     4261 tttccgaatc ccccatccca tcgccaatca gcaaaataat attttttgca ggtttatcgc
     4321 taagagaatc acgcagagcg gcagtctgat cacccgttaa acggcgagca ccgccgggtg
     4381 cagtaatatc gccctgagca gcccggtttt ccagaacagg catttctggt gtccgggctt
     4441 ttgtcacagg ggtaaacagt aacgataaga gtgccagtgc aatagtgctc tgtttcactt
     4501 tattttctcc atgtacaaat acattaaaaa ataaaaacaa agcgactata agtctcggcc
     4561 gtgacaactt tatgacagct gttgaaaaga ttaacttttt actgacgagg atgcttcaat
     4621 aacttcttta cgtaatcgcg cagcagctcc gtatcgtcgt caggaatgct ggcatcgggc
     4681 tttacctcgt acagcgcccc ctctacctga tcaatcaacc gctgttggtc attttgcgcc
     4741 atattgcgaa gcattgcagt gacgataatc tccaaagctt ctacctgcgc acacagttct
     4801 ttcgactctt cttctttttg ggcaagctta aataacaact cagcaatgag atttttcatg
     4861 tctgtatttc cttatccaaa gtatggagaa gttaacatta tgtttcacaa cttcatagtg
     4921 tctggaagta ttatttttat gacaaaggaa atactttgcg caaatatttt ttgtttgatt
     4981 accagcgaaa cgtttctctt atttaaataa ttacccacac aaaatatagg cttttaatta
     5041 tcaaccttta ttataaataa aagttatgaa atatattctc ttcgttaact tataattaag
     5101 agaaaaaaac tcaccgcatg gccatttaag ccaggaataa attagcttcc cgttcatcat
     5161 ttttgtgatc ttgcgcacat ctttgagata acgcactttc ttcaccagta cgttgcacgc
     5221 ttcgtcagca gaagattgca acaatctttc agaaggccgc gaatcccccg ttttgtcgtg
     5281 gtaatgtatg cactttgtgt tagacgggat aggtttttaa gatggaaaaa ctgcgggtag
     5341 gaatcgtttt tggtggtaaa tcagcggaac atgaagtgtc tctgcaatcg gcaaaaaaca
     5401 ttgtcgatgc cattgataaa agtcgcttcg acgttgtgct gctgggcatt gataaacaag
     5461 ggcaatggca cgtcagcgat gccagcaatt atctgctaaa tgcagacgat cctgcccata
     5521 ttgcgttacg cccttcggcg accagccttg cgcaggtgcc aggtaaacat gagcatcagc
     5581 ttatcgacgc gcaaaacggt cagccgttgc tgacggtgga tgtcattttc ccgattgtcc
     5641 acggtacgct gggcgaagat ggttccttgc agggaatgct gcgggtcgcc aatttaccgt
     5701 ttgtaggttc tgatgttctg gcttcagcag cctgtatgga taaagatgtc accaaacgtc
     5761 tgctacgcga tgccgggctg aacattgcgc catttattac tctgacgcgc gctaatcgtc
     5821 acaacatcag ttttgccgaa gtggagtcta aactggggtt accactgttt gtaaaaccgg
     5881 ctaatcaggg ctcttctgtt ggtgtcagca aagtaaccag tgaagaacag tacgcaattg
     5941 ccgtcgatct ggcgttcgag ttcgatcata aagtgatcgt tgagcaaggg atcaaaggtc
     6001 gtgagatcga atgcgcagtt ctgggcaacg acaatccgca agccagcacc tgtggcgaga
     6061 tcgtactcac cagcgatttc tatgcctacg acaccaagta cattgacgaa gatggcgcga
     6121 aagtggtagt tccggcagcc attgcaccag agatcaacga taagatccgg gcgattgccg
     6181 ttcaggctta tcagacgttg ggatgcgcag gcatggcgcg tgtagacgtg tttttaaccc
     6241 cagagaacga agtggtgatc aacgagatca acacactgcc tggcttcacc aacatcagta
     6301 tgtatccgaa gctgtggcaa gccagcggtc tgggttacac cgatctgatc acacgtttga
     6361 ttgagctggc gctggagcgt cacgctgcgg ataacgcatt gaaaaccaca atgtaatatt
     6421 ttaacgcccg ataatattct tattgggcgt tttcagtttc ttcatcgcga cgacgaataa
     6481 tcagccccgc cagccagaaa ctaatcaccc acgtcaccag accgacggca taggtctgcc
     6541 aaccttttgc ttcaaatccc agtaacccca ccacgccatt aagaatgaat ataaggccaa
     6601 tggcgaacgc atagtagtgc cagtcacggc ggatttttac aggcagattc atggcagctc
     6661 cgttaacgaa aaacaacatc cttgcatatt ctgtaacaac cgtctgtggt gtagacaaca
     6721 ttttcgtaat tgttaataaa tttaacttaa ggttgccatt ttgtgactca caacgaagat
     6781 tcacgcttcg ggaatattcc caacatcaat ttaccatgat tctgatattg acaatctaaa
     6841 tgacctgtca gacttgccat aagccgctgg tatcacacca gaagagaagc agatgacttc
     6901 cggaggtttt tatggctgat ttcaccctgt caaaatcgct gtttagcgga aaatatcgca
     6961 atgcctcttc aacgcctggc aacattgcct atgcgttgtt tgtgctgttt tgcttttggg
     7021 ctggggcgca attgctgaac ctgttagtgc atgcgcccgg cgtctatgag cgtttaatgc
     7081 aggtccagga aacaggtcgc ccacgggtgg aaattggttt aggtgtcggc accattttcg
     7141 ggctgatccc gtttttagta ggctgcctca tttttgcagt ggtggcgcta tggctgcact
     7201 ggcgacatcg ccgccagtaa gatttacgtt gccagatacg gcctaaaacg ccttatctgg
     7261 catgacattc ctgtttgatc actgtttcat acaacgcgcc cgccgttcgt ctacgcgctt
     7321 cgcaaaccag gccgtagtca ggttgcgggt gattttcggg ctttccagtt gaatgccagg
     7381 caacatttcg cggggtagtg atttacccgt tttcgcttcg gcaagttgat aaactttctt
     7441 gtacagcgcc gtctcctcaa aagagaagct gtcacctttc tctaactgac ggcgaatttc
     7501 gctgtcgctc atccccagtt ttgccgccag tttgcgcgtt gccagttcgg ttttcccggg
     7561 ttctttactg tcgtaacgaa ttaaatcacc gtccagtgcc agcttcacgc tgctggcctt
     7621 actgactgcg ttctgaaacg cggcattacg gctggcgtac cagccagcgt taaaatcagc
     7681 aaagcggtat atcggtgcgc tatagctggc gggataattc agtaaatggt aagtaccaaa
     7741 ccacaacccg ccgcggcgac tgaagacttc ctgacgaact gtaccgtcca ttttccacgg
     7801 ataccctttg gtatgctgtt cggcaaaagc aatgctgacc tgcatcggcc caccggtgcg
     7861 cacaggatta agcgaaccaa acagcgtctg ccccattggt accatgctga tcagatcgtc
     7921 aaaaatcgcg ctcaattgct tttctgtacg caccgaatct aaccgttcgc tataactttt
     7981 gccgtttggc gatttgattt ttagcgcggt atgaaccaga aaagcaggaa tgtgcatccg
     8041 ttcagcacga cggtcaatct cttgccaggc gatcttgctt aagcccggaa cggccggatc
     8101 tgcctgataa tttgactcct gctgcgccac cgccagcacc gagcagacgt tttccagcgt
     8161 cggtgccagc ccctgacttt caaaggtggt ggcgagatct ttcgcccagg catcgcggtc
     8221 tttcacgctc gcaggcatct tctgccgcac gacgctcgct acatctatcg ctttttcgcc
     8281 ctttttcaac ggttgcggag cctgactact acaccccgct aaaaccagaa ccgccaacaa
     8341 tgacagcgaa gatagatgat tgacgcgcga cattacttct cctttttagc tcaaggtatg
     8401 ggttacttcc tgaattttgt caccatccag ctcatgttca aagctgcgca gacgtttgta
     8461 gatagacatc aactcaacca gtgtggtcca tgagttaatc aggtactgga aagcaccgcg
     8521 aacctgacca aaaacgttgg taatctgcgt catcaggccg agcgtaatcg taccggcaac
     8581 aattgacgga aacagcaaga acaaaccgaa aacgttatcg acctgcaaat agagaatgcg
     8641 ggcgatgttg aaatacatat agtgaaaata gaggcgaaaa tagtttttcc gtacggcgct
     8701 aaacagctcg cgtaccgtag gcggcgtcgc gcgcgtggca tcgtcttcac cataaaccag
     8761 ctctttacgg taggcggcct ctactcgctg gtttttaaac tccagccccg gcagtttgat
     8821 ccctaccact gccagcaatc cggtccccat cagcgaccag acgatagcgg caatcaccag
     8881 accatacgga atgtgcccga taattggcag ctccggcaca tgcgcggaga gcgttaccag
     8941 caccggcaga aaggcgatca acgtcatgat ggcgttgata aaactgacgc ccatattctc
     9001 cagcgttgaa gcaaaacgca tggtgtcttc ctgcacacgc tgtgcggcac cttcgatatg
     9061 acgcagttgt tgccagttcg ccatgtaata ttcgttcatc gccgtacgcc agcggaacac
     9121 atagtgactg acaaagaagt tgttcagtac actgatcacc accgcgatca gcgcaatccc
     9181 cagaaagacg cccacttcgc ggtaaaattg ttcgatagtg actttatgcg gcgaacttag
     9241 cgcggtttga atcagatcat agaacggtgc ataccaggcg ttgacggcga ccccgacttc
     9301 caccaaaaac caggtgacga agatgatcag tgcagtaccg agtattgacc agtattgcca
     9361 acggtgcggg ctgtagataa accagaaaaa tgcaaaaagt cctacgcaaa caatgtagta
     9421 agcgtaaaaa atcaggaaat ccaacgacca gaaacgcgcg gcgctaatcg ggatctgccc
     9481 ggaagcgccg gtgatacgcg ccacccagtc acccccaccg gcttgccaga agataacggc
     9541 aatcaatgcc caaacaaagg ccgagagaaa aaacgctccc ggctttggga aaaaagactt
     9601 aaacatatgc actcctgcta acttcttatc gttttaacaa ctgctgtgta ttaaccgcat
     9661 gaccactaca aagcgtcagc caaatgaaac cgcccattgt gacccatagc aaggcgctta
     9721 gttcgccagc ctgaccataa gaattgtttc gacggatttc acaaaccaaa gattgtttac
     9781 ataagcggat taacacgcgc aggatcacaa atgcaggcat tggtgagcag gaaaaagatc
     9841 gtgtttacgc gccgttacgt ttttaacact attattgcac taattcgccc tttgcaatcc
     9901 atcaatgagt agtataaata cgctcagtta ccttcattca atctatggac accaccgttg
     9961 aaacgtagtc tgcttttttc tgccgtgctg tgtgcggcgt cattgacctc cgtccatgcg
    10021 gcgcagccga tcactgaacc ggagtttgcc tctgatattg tcgatcgtta tgccgatcat
    10081 attttttacg gcagcggtgc cacggggatg gcgctggttg ttatcgacgg taaccagcgc
    10141 gtctttcgta gttatggcga aacgcgacct ggtaataacg ttcgcccgca gctggattcg
    10201 gtcgtgcgta ttgcttccct caccaaacta atgaccagtg aaatgctggt gaaattgctc
    10261 gaccagggga ccgtaaagtt aaacgatccg ctaagtaaat atgctccgcc aggcgcacgc
    10321 gtgccgacct acaatgggac gcccattacc ctagtgaatc tggcaaccca taccagcgcc
    10381 ctgccccgtg aacagcccgg tggcgcggca catcgtccgg tgtttgtctg gccaacgcgc
    10441 gaacaacgct ggaaatacct ttctacggcg aagctaaaag ccgcgccagg cagtcaggcg
    10501 gcgtactcta accttgcgtt cgacctgctg gcagatgcac tggcgaatgc gtccggcaag
    10561 ccttataccc agttgtttga agagcagatt acccgtccat tggggatgaa agacaccacc
    10621 tacaccccct caccggatca gtgccgccgt ttaatggttg ctgagcgcgg tgccagtccg
    10681 tgcaataaca cgctggcggc aattggcagc ggcggcgtct attccacgcc tggcgatatg
    10741 atgcgctgga tgcagcagta tttgtcatct gatttttatc agcgcagtaa ccaggcagat
    10801 cgcatgcaga cgttgattta tcagcgcgcg cagtttacga aagtgattgg catggatgtc
    10861 cccggcaaag cggatgcgct tggtttaggc tgggtatata tggccccgaa agagggtcgt
    10921 ccggggatta ttcagaagac aggaggtggt ggcggtttca ttacctatat ggcgatgatc
    10981 ccgcagaaga atattggcgc gtttgtggtg gtcactcgtt cgccgttgac gcgctttaaa
    11041 aatatgagcg atggcatcaa tgatctggtg accgagctaa gcgggaataa accgttggtt
    11101 atccccgcat cctgattaat actctgaagg caaacggttg atagcgacca gtttgccttt
    11161 attcatttcg atatagccgc ctttacgcaa agcagcgaga acttctgcga cgacagaacg
    11221 cgatatgcgt gtacgttgat ggatataatt catcacacca atacgtgatc gcaattcttc
    11281 attccagtca atcattgata ataatgttgc gcggatttgt tcgtaggaat tatgcccaat
    11341 gagctgcacg tcgcgtaatt ccagaattct attttgccag gctaaccagt aaaaagcgtc
    11401 tcgccagagt tgattttgtt caataagcgt aatggtttgt ttggctggta gatgatatcc
    11461 cgtacaattt ccttctgata ttaatttgta tggtatatcg tttttcatta aaccatcagc
    11521 cagccccata atataaggag cctgggtaat accgataagt acgttttctt ctctacgcag
    11581 agagataacg ccctctaaaa taacgaaagt attttcgcta ttgacatcac tggaaaatat
    11641 aacttgcttt tcattattaa actcgaagcg cgtaccgtat ctggacaaac atttatcgag
    11701 cttaccaaat tcctgaagag gtttaactac agataacatt tgcgcgtcct ttgcagtaat
    11761 gcccgtcaaa tccttgacgg gcattattta gattaaatta ccagaatttc ttcggagtga
    11821 agaatattac caggtatatt taacacccac gttcgcggac cagtcttgat ctacgtcacc
    11881 accaccgagg tagttagcat cggtataggc gctgaagttc ttggtgaagc tgaactgagt
    11941 acccagacca acacgtaccg cagacccttc agtaccgtta tcgatggaat caccgttcac
    12001 atcgttatcg ttgttagagt cgtcgtagac gtaagccagt ttgaagtacg gagtcagagc
    12061 ctgatcttcg ctgtaggtga aggtataacc tgcatctaca cccagttcat aacgcatgct
    12121 gtcgtaagac tgaccgtcaa ctttcatgtc gttgctcagc tggtagtcat caccagactg
    12181 gaacagacca gaaacgctgc cgtaaggagt cacgtaacca gcatcaccca gtttgaagtc
    12241 gtaaccggct ttcaaaccga agccccacgc gtcagagttg gtgctaccgt caacgtaagt
    12301 accgttgctc atggttgcag acaggtcgtt gttgaagtga gagtagctca agctaccatc
    12361 aacaaagacg ttgttcgcga agtgagcaga agagtagatg taggcagtct ggctgtcttg
    12421 atccacctga ccagaacggt cattcatgtc acctttagcg aagcctgcag ccgcaccgac
    12481 gatccactta gcgttgttac cgtcaatttt ggtatcaaca ccgaccatga tgccgttaac
    12541 atcctgatca tagttgatgg tgccgttgtc gccgttgaag ttaccaccga agtagcttac
    12601 ccatgcgccg ccgttatcag ccaggccatg acgagagttg gtcagacgag taccaacggt
    12661 gtcttgttcc aggttccaga tattggtgtt cgcagacggg atgctcagtg ccatgttagc
    12721 gtagtcggtc agctccatct gttgcagaac aacggtgtta ccgcgctgtt cagcctgata
    12781 ggtgtatgca cccaggtcag ctttgttagc agcagagaag gtcgcgttgg tgttgacgtc
    12841 gtttacgtag ataatttctt tatctttgta atcagcgata gcgccagcgc cagttgcgtt
    12901 gtcgatacga actttgtagt taccggttgc agcaacaacg ttatcaacag agctgttatc
    12961 cagttcagta ccgttgtcta cgtcgccgtt accattgata gtcaggtgac cgtcagagtt
    13021 catagcaaca ataccgtaac cgtagttaga cttggaagta tcccacgtac ggtcgttcac
    13081 cagatcagcg ttcagaacgt aatcgctgct atggatatcg aacacaccag atactacgtt
    13141 accgttatgg tcagcgatgt tgccgctggt cagttccagt ttgtcagtac ggaaagcttc
    13201 agtatcgaac tgatcaacgt tcacatccaa tacaccaccg ttagttacgg tgatagtatt
    13261 ggcgtacagg ttgtaatcag ccccccaccc agtagattcg gtcaacgcaa cagtactgta
    13321 ggagttaata gtcagatgat cggtatcaac gtagccatct tcaccaatgt tcagcgaaga
    13381 accgttagtt aaatcgatag tatctgaagt taatttagat tccgaaacat taacctgaga
    13441 accattatta actgtcaagg tatcaacgat ggaacgacct gtagtatccc attcagaacc
    13501 gttattcaac gctacgttaa atacaccgct ctggaagacc ttgtcatcaa caacacgttt
    13561 ccagtcattg ttttcatatg ttgcatcagg agtaaggctg tttgtagcaa catcatacat
    13621 tgctgacgtt tcagcaacgt tataaattgc ctgaccaacc cacttgcttc cgttatcgag
    13681 agtgagattt agttcatcaa cgttgaggct atcatcagtc caacccccgt tggtatcttt
    13741 caccccgtca ccgttggaat catgaccatt cggatcaaaa ttactattcc aggtgctggt
    13801 aaaggcaaca tcacccatca gcgttgaatt gctgaggaat acattgttct tcatcgcata
    13861 gtcggaacct gaagcagtaa aggacattgc aacatcaccc gggccagcat aatcactcgg
    13921 ttcatcagaa ttgccaaagt gaccagtttt gccataagta ttgctatcca ggatataatt
    13981 tgaacccgaa gtcactgtgg aatcttttac agagatattg ttatcccaag tatgagattc
    14041 ggtagtgtag gtttcgttgt aagtattacc ttgagataat gcaatacctg caacgcggga
    14101 gttattggaa atattgatgt tactttctac atcaagatta acagcaacgc cttcacttgt
    14161 atcaaatgtc tcatttgtgt gcttggttac atcaccatct ttataagaat cagtgaagta
    14221 aagagcttca taatcatcat caatagtagt gttagcaatg ttcaaagtga aaacatcacc
    14281 atcacgccag tgtgtatcaa caaccgcatc agtgtaaaaa tcatatccac ccagattatt
    14341 accatctgca tcaaaacgat cataataacc gccaggcagc atagaagtaa tcgaaccgtg
    14401 aatcactgaa ttactgatat caagctgatt agcagtactg tctgcataat catggttcaa
    14461 ataataggtt gagattgtcc cgttaacggt atcgccgtta aaggactgat cgaaatcacc
    14521 attggtgttg ttgtaataga caaaaccact atagtttaca tagttgccat ctacagtgcc
    14581 tgccttatcc atatgatccc aatcaagtgc tgtaacggga ttatcgatat aagtccaggt
    14641 atcatagttt gctgcattag cctgagaggt gatagccaga gtgcaagcca atgctaattg
    14701 tgatactaca agtttctttt tccaggagtg catttgtcat ccctcctcag ggacgtaata
    14761 agttgatcca tcaattatca atgcatagaa aacatattat gtttcgcgct aacgattatg
    14821 ctgcgttaca gacgaatggt tcaattattc tttcccctaa gtccgaatgt ggacatatat
    14881 aatttatgga gaaaaacacg catcaaattg ataaaaggac gatatttcaa catgttgcag
    14941 ataatgttat ttttgataca tacgcgttat aaatatcaa
//
LOCUS       DAPGUL010000110        14564 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.112, whole genome shotgun sequence.
ACCESSION   DAPGUL010000110 DAPGUL010000000
VERSION     DAPGUL010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14564
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.112"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..354)
                     /gene="quuD"
                     /locus_tag="RHX21_003608"
     CDS             complement(<1..354)
                     /gene="quuD"
                     /locus_tag="RHX21_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein QuuD"
                     /protein_id="HDV1988739.1"
                     /translation="MRDIQMVLERWGAWAANNHEDVTWSSIAAGFKGLIPSKVKSRPQ
                     CCDDDAMIICGCMARLKKNNSDLHDLLVDYYVVGMTFMSLAGKHCCSDGYIGKRLQKA
                     EGIIEGMLMALDIRLE"
     gene            complement(440..580)
                     /locus_tag="RHX21_003609"
     CDS             complement(440..580)
                     /locus_tag="RHX21_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlcG family protein"
                     /protein_id="HDV1988740.1"
                     /translation="MMFEFYMAELLRHRWMRLRLYRFPGSVLTDYRILKNYAKTLTGA
                     GV"
     gene            complement(577..939)
                     /locus_tag="RHX21_003610"
     CDS             complement(577..939)
                     /locus_tag="RHX21_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDV1988741.1"
                     /translation="MNTYNITLPWPPSNNRYYRHNRGRTHISAEGQAYRENVARIIKN
                     AMLDIGLAMPVKIRIECHMPDRRRRDLDNLQKAAFDALTKAGFWLDDAQVVDYRVVKM
                     PVVKGGKLELTITEQGDE"
     gene            complement(936..1025)
                     /locus_tag="RHX21_003611"
                     /pseudo
     CDS             complement(936..1025)
                     /locus_tag="RHX21_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309645.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1364 domain-containing protein"
     gene            complement(1146..1487)
                     /locus_tag="RHX21_003612"
     CDS             complement(1146..1487)
                     /locus_tag="RHX21_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001673929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2591 family protein"
                     /protein_id="HDV1988742.1"
                     /translation="MDYSQLSDFEINRMVGDIIFKGLWASKPETSGNNTNKWYYGNAD
                     TTFEPLNHLPDYCNDPSASWPIIEKYRISILDQLTEWCVDAKGVSPIFDTRPLRAAMI
                     VFLLMQEANNA"
     gene            complement(1490..1666)
                     /locus_tag="RHX21_003613"
     CDS             complement(1490..1666)
                     /locus_tag="RHX21_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NinE family protein"
                     /protein_id="HDV1988743.1"
                     /translation="MRRQRRSFTDIICENCKYLPTKRSRNKRKPIPKESDVKTFNYTA
                     HLWDIRWLRYRARK"
     gene            complement(1663..2190)
                     /locus_tag="RHX21_003614"
     CDS             complement(1663..2190)
                     /locus_tag="RHX21_003614"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage N-6-adenine-methyltransferase"
                     /protein_id="HDV1988744.1"
                     /translation="MTIKSNTPAHDKDCWQTPLWLFDALDIEFGFWLDSAASDKNALC
                     AHWLTEADDALNSEWVSHGAIWNNPPYSNIRPWVEKAAEQCIQQRQTVVMLVPEDMSV
                     GWFSKALESVDEVRIITDGRINFIEPSTGLEKKGNSKGSMLLIWRPFISPRRMFTTVS
                     KAALMAIGQGVRRAA"
     gene            complement(2187..2627)
                     /locus_tag="RHX21_003615"
     CDS             complement(2187..2627)
                     /locus_tag="RHX21_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein NinB"
                     /protein_id="HDV1988745.1"
                     /translation="MKKLTFEIRSPAHQQNAIHAVQQILPDPTKPIVVTIQERNRSLD
                     QNRKLWACLGDVSRQVEWHGRWLDAESWKCVFTAALKQQDVVPNLAGNGFVVIGQSTS
                     RMRVGEFAELLELIQAFGTERGVKWSDEARLALEWKARWGDRAA"
     gene            complement(2701..2991)
                     /locus_tag="RHX21_003616"
     CDS             complement(2701..2991)
                     /locus_tag="RHX21_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein ren"
                     /protein_id="HDV1988746.1"
                     /translation="MKGKEAIIHYLGTHNSFCAPDVAALTGATVTSINQAAAKMARAG
                     LLVIEGKVWRTVYYRFATREEREGKMSTNLIFKECRQSAAMKRVLAVYGVKR"
     gene            complement(2988..3689)
                     /locus_tag="RHX21_003617"
     CDS             complement(2988..3689)
                     /locus_tag="RHX21_003617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Replication protein P"
                     /protein_id="HDV1988747.1"
                     /translation="MKNIAAQMVDFDREQMRRIANNMPEQYDEKPQVQQVAQIINGVF
                     SQLLATFPASLANRDQNELNEIRRQWVLAFRENGITTMEQVNAGMRVARRQNRPFLPS
                     PGQFVAWCREEASVIAGLPNVSELVDMVYEYCRKRGLYPDAESYPWKSNAHYWLVTNL
                     YQNMRANALTDAELRRKAADELTCMTARINRGETIPEPVKQLPVMGGRPLNRAQALAK
                     IAEIKAKFGLKGASV"
     gene            complement(3686..4578)
                     /locus_tag="RHX21_003618"
                     /pseudo
     CDS             complement(3686..4578)
                     /locus_tag="RHX21_003618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311014.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
     gene            complement(4611..4907)
                     /locus_tag="RHX21_003619"
     CDS             complement(4611..4907)
                     /locus_tag="RHX21_003619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988748.1"
                     /translation="MEQTNYSKLSQRDVDRAETDLLINLSTLTQRGLAKMIGCHESKI
                     SRTDWRFIASVLCAFGMASDLSPISRAFKYALDEITNKKRPAATERSEQIQMEF"
     gene            complement(5049..5264)
                     /locus_tag="RHX21_003620"
     CDS             complement(5049..5264)
                     /locus_tag="RHX21_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDV1988749.1"
                     /translation="MSNLRKYRESLNISQTTLAKAVGCTQGAIGHWESGRRFPDLKTC
                     RALVACLNKLGAKVSLDDVFPPEHKAA"
     gene            5340..6035
                     /locus_tag="RHX21_003621"
     CDS             5340..6035
                     /locus_tag="RHX21_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019842863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HDV1988750.1"
                     /translation="MDGCNTERNNKDMKMKWYELARSRMKELGITQEKLAEELGMTQG
                     GIGHWLRGSRHPSLSDIGVVFKYLGIDNISFNHDGTFSPVGEYSSAPVKKQYEYPVFS
                     HVQAGMFSPELRTFTKGDAERLVSTTKKASDSAFWLEVEGNSMTAPTGSKPSFPDGML
                     ILVDPEQAVEPGDFCIARLGGDEFTFKKLIRDSGQVFLQPLNPQYPMIPCNESCSVVG
                     KVIASQWPEETFG"
     gene            6208..6504
                     /locus_tag="RHX21_003622"
     CDS             6208..6504
                     /locus_tag="RHX21_003622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000854876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1902 domain-containing protein"
                     /protein_id="HDV1988751.1"
                     /translation="MKTLRCMAYQQNGVYVAACLDLSLAAQADTMKEAVNKLDEQIKD
                     FFTEALSEPEYAKQLLSRKAPLSMWLKYWVIAFQVFVRKRGEAKLFAEPCDAHA"
     gene            6516..6800
                     /locus_tag="RHX21_003623"
     CDS             6516..6800
                     /locus_tag="RHX21_003623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000478870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HDV1988752.1"
                     /translation="MFLKKLTPLKYDEVIRGLKKMGFEMKPKTGTSHEQWVLKNSKGK
                     WVVTVDKHHAPFSRDLIKSMAKQAGLKARHFHALCRGDATLEDIGFQIIS"
     gene            7033..7255
                     /locus_tag="RHX21_003624"
                     /pseudo
     CDS             7033..7255
                     /locus_tag="RHX21_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502599.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            7233..7505
                     /locus_tag="RHX21_003625"
     CDS             7233..7505
                     /locus_tag="RHX21_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein N"
                     /protein_id="HDV1988753.1"
                     /translation="MSRKTEFKGTAASRRRARRANLQSQKAISSDKLHRPTPSRVVLQ
                     CKRKPAMRAEVITLTTLTRKYEGSTCLPNVALYAAGYRKSKQLTAR"
     gene            7634..7731
                     /locus_tag="RHX21_003626"
                     /pseudo
     CDS             7634..7731
                     /locus_tag="RHX21_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213972.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            7790..8239
                     /locus_tag="RHX21_003627"
     CDS             7790..8239
                     /locus_tag="RHX21_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988754.1"
                     /translation="MEEQANKILVELLQKASNGIDAAVSFSQAQIPDVVHQLLLWNMV
                     DSLIKTLMAILTIPLVFWFMKKQCQRVETGKIGDEGYSWEKGNPKYRPTMVWDSKGDI
                     NLLIMPLVGVLTLWGIFIIGVVTNMTWLKIWLAPKLYLIEYAASLVK"
     gene            8435..8803
                     /locus_tag="RHX21_003628"
     CDS             8435..8803
                     /locus_tag="RHX21_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2528 family protein"
                     /protein_id="HDV1988755.1"
                     /translation="MSNIKKYIIDYDWKASIEIEIDHDVMTEEKLHQINNFWSDSEYR
                     LNKHGSLLNAVLIMLAQHALLIAISKDLNAYGVVCEFDWDDGNGQEGWPPMDGSEGIR
                     ITDIDTSGIFDSDDMTIKAA"
     gene            8876..9040
                     /locus_tag="RHX21_003629"
     CDS             8876..9040
                     /locus_tag="RHX21_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease FtsH-inhibitory lysogeny factor CIII"
                     /protein_id="HDV1988756.1"
                     /translation="MQYAIAGWPVAGCPSESLLERITRKLRDGWKRLIDMLNQPGVPK
                     NGSNTYGYPD"
     gene            9009..9152
                     /gene="kil"
                     /locus_tag="RHX21_003630"
     CDS             9009..9152
                     /gene="kil"
                     /locus_tag="RHX21_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309204.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host cell division inhibitory peptide Kil"
                     /protein_id="HDV1988757.1"
                     /translation="MDQTLMAIQTKFTIATFIGDEKMFREAVDAYKKWILILKLRSSK
                     SIH"
     gene            9226..9522
                     /locus_tag="RHX21_003631"
     CDS             9226..9522
                     /locus_tag="RHX21_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309203.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host-nuclease inhibitor protein Gam"
                     /protein_id="HDV1988758.1"
                     /translation="MNAYYIQDRLEAQSWARHYQQIAREEKEAELADDMEKGLPQHLF
                     ESLCIDHLQRHGASKKAITRAFDDDVEFQERMAEHIRYMVETIAHHQVDIDSEV"
     gene            9528..10313
                     /gene="bet"
                     /locus_tag="RHX21_003632"
     CDS             9528..10313
                     /gene="bet"
                     /locus_tag="RHX21_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage recombination protein Bet"
                     /protein_id="HDV1988759.1"
                     /translation="MSTALATLAGKLAERVGMDSVDPQELITTLRQTAFKGDASDAQF
                     IALLIVANQYGLNPWTKEIYAFPDKQNGIVPVVGVDGWSRIINENQQFDGMDFEQDNE
                     SCTCRIYRKDRNHPICVTEWMDECRREPFKTREGREITGPWQSHPKRMLRHKAMIQCA
                     RLAFGFAGIYDKDEAERIVENTAYTAERQPERDITPVNDETMQEINTLLIALDKTWDD
                     DLLPLCSQIFRRDIRASSELTQAEAVKALGFLKQKATEQKVAA"
     gene            10310..10990
                     /locus_tag="RHX21_003633"
     CDS             10310..10990
                     /locus_tag="RHX21_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HDV1988760.1"
                     /translation="MIPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKP
                     RSGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYENDARTLFEFTSGVNITE
                     SPIIYRDESMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQY
                     SMWVTRKDAWYFANYDPRMKREGLHYVVVERDEKYMASFDEMVPEFIEKMDEALAEIG
                     FVFGEQWR"
     gene            10987..11169
                     /locus_tag="RHX21_003634"
     CDS             10987..11169
                     /locus_tag="RHX21_003634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1317 domain-containing protein"
                     /protein_id="HDV1988761.1"
                     /translation="MKHPHDNIRVGAITFVYSVTKRGWVFPGLSVIRNPLKAQRLAEE
                     INNKRGAVCTKHLLLS"
     gene            11142..11333
                     /locus_tag="RHX21_003635"
     CDS             11142..11333
                     /locus_tag="RHX21_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1382 family protein"
                     /protein_id="HDV1988762.1"
                     /translation="MHKASPVELRTCIEMAHSLAQIGVRFVPIPVETDEEFHTLAASL
                     SQKLEMMVAKAEADERDQV"
     gene            11410..11625
                     /locus_tag="RHX21_003636"
     CDS             11410..11625
                     /locus_tag="RHX21_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HDV1988763.1"
                     /translation="MTPQQENALRSIARQANSEIKKARQQFPDKNVDDICRSVLKKHR
                     ETVTLMGFTPTHLSLAIGMLNGVFKER"
     gene            11724..11942
                     /locus_tag="RHX21_003637"
     CDS             11724..11942
                     /locus_tag="RHX21_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016246897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA family transcriptional regulator"
                     /protein_id="HDV1988764.1"
                     /translation="MADIIDSASEIEELQRNTAIKMRRLNYQTVSATHCCECGDPIDE
                     RRRLAVQGCRTCASCQEEIELKNKQWGL"
     gene            11990..12268
                     /locus_tag="RHX21_003638"
     CDS             11990..12268
                     /locus_tag="RHX21_003638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4222 domain-containing protein"
                     /protein_id="HDV1988765.1"
                     /translation="MFRIIFPNTWYVDHHGTPCKILRSTHNKVHYIRKGRTCIASMFR
                     FNHDFEPVNKADADRIAEEIETAEHIKKLRDMRSKSRGNHGIIQPHTR"
     gene            12467..13630
                     /locus_tag="RHX21_003639"
     CDS             12467..13630
                     /locus_tag="RHX21_003639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDV1988766.1"
                     /translation="MSLFRRNEIWYASYSLPGGKRIKESLGTKDKRQAQELHDKRKAE
                     LWRVEKLGDLPDVTFEEACLRWLEEKADKKSLDSDKSRIEFWLEHFEGIRLKDISEAK
                     IYSAVSRMHNRKTKEIWKQKVQAAIRKGKEPPVYEPKPVSTQTKAKHLAMIKAILRAA
                     ERDWKWLEKAPVIKIPAVRNKRVRWLEKEEAKRLIDECPEPLKSVVKFALATGLRKSN
                     IINLEWQQIDMQRRVAWVNPEESKSNRAIGVALNDTACKVLRDQIGKHHKWVFVHTKA
                     AKRADGTSTPAVRKMRIDSKTSWLSACRRAGIEDFRFHDLRHTWASWLIQSGVPLSVL
                     QEMGGWESIEMVRRYAHLAPNHLTEHARKIDDIFGDNVPNMSHSGIMEDIKKA"
     gene            complement(13646..13722)
                     /locus_tag="RHX21_003640"
     tRNA            complement(13646..13722)
                     /locus_tag="RHX21_003640"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13686..13688),aa:Arg,seq:tct)
     gene            13965..>14564
                     /gene="fimZ"
                     /locus_tag="RHX21_003641"
     CDS             13965..>14564
                     /gene="fimZ"
                     /locus_tag="RHX21_003641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria biosynthesis transcriptional regulator
                     FimZ"
                     /protein_id="HDV1988767.1"
                     /translation="MKPTSVIIMDTHPIIRMSIEVLLQKNSELQIVLKTDDYRITIDY
                     LRTRPVDLIIMDIDLPGTDGFTFLKRIKQIQSTVKVLFLSSKSECFYAGRAIQAGANG
                     FVSKCNDQNDIFHAVQMILSGYTFFPSETLNYIKSNKCSTNSSTVTVLSNREVTILRY
                     LVSGLSNKEIADKLLLSNKTVSAHKSNIYGKLGLHSIVEL"
BASE COUNT         4014 a         3394 c         3369 g         3787 t
ORIGIN      
        1 ctctaaccgg atatctaatg ccattaacat cccttcaatt atgccctcag ccttctgtaa
       61 ccttttcccg atataaccat cagagcagca atgcttacct gccagtgaca tgaatgtcat
      121 accgactaca taataatcta ctaataaatc atgcaaatcg ctgttgttct ttttcagacg
      181 ggccatgcac ccgcaaatga tcatcgcgtc atcgtcacaa cattgtgggc gagattttac
      241 ttttgaagga attaatccct taaaaccggc ggcaatggac gaccaggtca catcttcatg
      301 attattagcc gcccacgctc cccaacgctc aagaaccatc tgaatatcac gcatcaactt
      361 actccacaaa actcagacca gaacgccaat tacaagcaaa aatcaacaaa acagtattag
      421 ttgattgtta tctctgactt catactcctg ctcctgtcag tgttttggcg taattcttca
      481 gtattcggta atcggtcaaa acagaaccgg ggaaacgata taagcgcagg cgcatccagc
      541 ggtggcgaag aagttctgcc atataaaact caaacatcat tcatctccct gttcagtgat
      601 ggtcagttcc agctttccac ctttgacaac cggcatcttc acaacgcggt aatcaacgac
      661 ctgagcatca tccagccaga aacctgcttt ggtgagtgcg tcaaaagcgg ccttttgtag
      721 attatccagg tcacggcgac ggcgatccgg catgtgacac tcaatgcgga ttttcacagg
      781 catagccagg ccgatatcca gcattgcgtt tttaatgatt cgggcgacgt tttcgcggta
      841 tgcctgcccc tctgcgctga tgtgcgtgcg cccgcgatta tggcggtaat agcgattatt
      901 gctcggcggc cagggtaatg tgatattgta ggtattcacg ccttaataac cccctctttc
      961 agccagataa actgtgttct cgccatacct tccagcgcgc attcttttgc atatgcagca
     1021 tcgacttgct tggcatgccc tttaccggca atcttctgta tgcgctaaac ctagatagaa
     1081 tccactctgt gcacattgaa gcccgctcta tgcttccttt caggtattga agggattgag
     1141 atgggctaag cattattggc ctcctgcatc aggagaaaga caatcatggc ggcgcggaga
     1201 ggtctggtat caaatattgg gcttacgcct tttgcatcca cacaccattc agttaactgg
     1261 tctaagatag aaatcctgta tttctcaata atcggccatg aagcgctcgg atcattgcag
     1321 tagtcaggca aatgatttaa tggctcaaaa gttgtatcag catttccgta ataccatttg
     1381 ttggtgttat tccctgatgt ttccggttta cttgcccaaa ggcctttaaa aattatgtct
     1441 cctaccattc tgttaatttc aaaatcactt aactgtgaat aatccattgt catttcctcg
     1501 cacgatatct tagccaccgg atatcccaca ggtgagctgt gtaattgaag gtttttacgt
     1561 cagattcttt tgggattggc ttgcgtttat ttctggagcg tttcgttgga aggtatttgc
     1621 agttttcgca gatgatgtcg gtgaaacttc gtcgctgtcg cctcatgccg ccctcctgac
     1681 gccctgcccg atcgccatca atgccgcttt ggatacggta gtaaacatcc gtcgaggact
     1741 gatgaacggt cgccaaatca gcagcatgga gcctttgctg tttcccttct tctccagccc
     1801 tgtcgatggt tcgataaaat taatccgtcc atcagtgata atgcgaactt cgtcgacact
     1861 ctccagagcc ttgctgaacc atccgactga catatcctct ggcacaagca taactaccgt
     1921 ctgtcgctgt tgtatgcact gctcagcagc tttttccacc cacggcctga tattgctgta
     1981 cggtgggtta ttccagattg caccgtggct tacccactca gaattgagcg cgtcgtcggc
     2041 ctcagttagc cagtgagcac acagagcatt tttgtcgctc gctgccgaat ccagccagaa
     2101 tccaaactca atatccagtg catcaaaaag ccaaagcggc gtttgccagc agtccttgtc
     2161 gtgtgctggc gtatttgatt tgatagtcat gcagcccgat ctccccatct cgctttccac
     2221 tccagagcca gtctcgcttc gtctgaccac ttaacgccac gctctgtacc gaatgcctgt
     2281 ataagctcta atagctccgc aaattcgcct acacgcatcc tgctggttga ctggcctatt
     2341 accacaaagc cattcccggc aaggttagga acaacatcct gctgctttaa tgctgcggta
     2401 aacacacact tccagctttc tgcatccagc cagcgaccat gccattcaac ctgacgagag
     2461 acgtcaccta agcaggccca tagcttcctg ttttggtcta agctgcggtt gcgttcctga
     2521 atggttacta cgattggttt ggttgggtct ggaaggattt gctgtactgc gtgaatagcg
     2581 ttttgctgat gtgctggaga tcgaatttca aaggttagtt ttttcatgac ttccctctcc
     2641 cccaaataaa aaggcctgcg attaccagca ggcctgttat tagctcagta atgtagatgg
     2701 tcatctttta actccatata ccgccaatac ccgtttcatc gcggcactct ggcgacactc
     2761 cttaaaaatc aggttcgtgc tcatctttcc ttcccgttct tccctggtag caaaccggta
     2821 atacaccgtt cgccagacct taccttcgat aaccagaaga cctgcccgtg ccattttagc
     2881 cgcggcctga tttatgctgg ttactgttgc gcctgttagc gcggcaacgt ccggcgcaca
     2941 gaagctatta tgcgtcccca ggtaatgaat aattgcctct ttgcccttca tacacttgct
     3001 cctttcagtc cgaacttagc tttaatttct gcgatcttcg ccagagcctg tgcacgattt
     3061 agaggtctac cgcccataac aggaagttgt tttactggtt caggtatcgt ctcaccacgg
     3121 ttaattcgcg ctgtcataca ggtcagttca tcggcagcct tgcgccgtaa ttccgcatca
     3181 gtaagcgcat tggcccgcat gttctgatac aggttggtaa ccagccagta gtgcgcgttt
     3241 gatttccacg gataagactc cgcatccgga tacaggcctc gcttccggca atactcgtaa
     3301 accatatcaa ccagctcgct gacgtttggc agtccggcga taacggatgc ttcttcccgg
     3361 caccatgcaa caaactgccc gggtgatggc agaaatggtc gattctgccg acgggctacg
     3421 cgcattcctg cgttaacctg ttccatcgtg gtgatcccgt tttcccgaaa agccagaacc
     3481 cactggcgac ggatttcgtt cagttcgttc tggtcacggt tagccagact cgccgggaaa
     3541 gttgccagta actggctgaa cacaccgttg atgatctgcg ctacctgctg tacctgcggc
     3601 ttttcgtcgt actgttccgg catgttgttg gcgatccgac gcatctgctc acggtcaaag
     3661 tcaaccatct gtgcggcgat gtttttcata gatccacccc gtaaatccag tctgtgtttg
     3721 tcaggtcgag ttttggtttg ctggctgtca cgactgcctg ttgcttgtta cggttgattt
     3781 cgagctgggt ccacttgtcg cggagtttgg ccgggctaag cacgttaccg gaccagaagt
     3841 tgtcctggca tgcccagcgg aacagtacac acatgtcgcg atggttacgt ccgtcacgtt
     3901 cacgcatcag gcggatatcg ttagcccacc cagcaaaatt cggttttctg gctgatggtg
     3961 cgatagtctt caccatgtca aacatccact ctgcggcggt caggtcttct gctgtccccc
     4021 acttgctgcc gctctgaatt gcagcatccg gtttcaccac agaaaggtcg ttttctggct
     4081 ggtcagagga ttcgccagaa ttctctgacg aataatcttt tcttttgtaa tagtgtcttt
     4141 tgtgtccccc tgttttgagg gatagcaatc ccccaatttg agggatgttt tatccctcgt
     4201 tttaggggat tttccctcgt tttgagggat acaccattct gagatgtttt tatttggtcc
     4261 aaacatgccg ccttgctgct tgataatatt cattctgacg agttctaact tggcttcatt
     4321 gcaccgtttg acgggtaact ttgtaatctc gctaagttga gaatcggtga ttctgtccat
     4381 tggtttattc cacccatagg ttttacgcag aatggcaagc agcactttaa actgtcgctt
     4441 ggtcagatct gcgcccgaat aagcctcaag cagcatattt gatagtctgg cgtaaccatc
     4501 atcgagatct gccacattac gctcctgtcc ggcaaagtta cctctgccga agttgagtat
     4561 ttttgctgtg tttgtcataa tgactcctgt tgatagatcc agtaatgacc tcagaactcc
     4621 atctggattt gttcagaacg ctcggttgcc gccgggcgtt ttttattggt gatttcatca
     4681 agcgcatact taaaagctct gctaatcgga ctgaggtctg atgccatgcc aaaagcacac
     4741 aagaccgaag ctataaacct ccagtctgtt ctgcttatct tcgattcatg acagccaatc
     4801 atctttgcca gaccgcgctg agtaagcgtt gacaggttga taagtaaatc tgtttctgcg
     4861 cgatcaacgt cgcgctgtga tagtttgctg taatttgttt gttccatttc ttaagatttc
     4921 caatagtgaa tagttagttg aaaggtatgc gtggaaacgc atatggcctt agttggtcag
     4981 atatcttggg gctcgctttt cagcgacgta ggacgaatgt ccgttgttac aaagagcggc
     5041 tccgcttatt aagcggcttt gtgctccggc gggaacacgt catcaagact tacttttgcg
     5101 cctaacttgt ttagacacgc aacaagagca cggcatgttt taaggtctgg gaagcgacga
     5161 ccagattccc aatgtccgat agctccctgt gtgcatccaa ctgccttagc aagtgttgtt
     5221 tgagagatat tcagtgactc tcgatatttt cgtaggttgc tcatatgccc tccatagtaa
     5281 ccatgaagaa aaaaatacaa tatgtacttt tttaatgcaa gcaaaaatac acattgtgca
     5341 tggatggttg caatacagag cgtaataata aggacatgaa aatgaaatgg tatgaactgg
     5401 ctagatccag aatgaaagag ctcggcataa ctcaagagaa gttagccgaa gagctaggta
     5461 tgacgcaggg tggaattgga cactggttgc gcggatctcg tcatccatct cttagtgata
     5521 ttggtgtggt gtttaaatac cttggtattg ataacatatc attcaaccac gacgggacat
     5581 tttcacctgt tggcgaatac tcatcggccc cagttaaaaa acaatatgag taccctgttt
     5641 tttctcatgt tcaggctggg atgttctctc cagaactcag aacctttacc aaaggcgatg
     5701 cggagagatt ggtaagcaca accaaaaaag ccagtgactc tgcattctgg cttgaggttg
     5761 aaggtaactc gatgaccgcc ccaacaggtt ccaaacctag ttttcctgac gggatgttaa
     5821 ttctggttga ccctgagcag gctgttgagc caggtgattt ctgcatagcc agacttggtg
     5881 gtgatgagtt taccttcaag aaactgatca gggatagcgg tcaggtgttt ctacagccac
     5941 taaacccgca atatccaatg atcccatgca atgagagttg ttccgttgtg gggaaagtta
     6001 tcgccagcca gtggccagaa gagacgtttg ggtaatttct ctgtttgttt tttaagctat
     6061 caatctctgg cttgtggata agttggaagg tattcgctgc taatgtattg acatttacaa
     6121 aatataggta ttttggggtt gtctaaaatt acctataggg taaacttcac ttaagctcct
     6181 acatgagagc ttctgaggag agataaaatg aaaaccttac gttgcatggc ctaccagcag
     6241 aacggcgttt acgtagctgc atgtttagac ctgtcattgg cagcgcaagc agatactatg
     6301 aaagaagctg taaacaaact ggatgagcag attaaagatt ttttcactga agcgctatca
     6361 gagccggaat atgcaaaaca actactaagt cggaaagcac ctttatctat gtggcttaag
     6421 tattgggtaa ttgcatttca ggtttttgtc agaaaacgag gtgaagcaaa actctttgct
     6481 gagccttgtg atgctcatgc ttagggttac attacatgtt cttgaaaaag cttactcctt
     6541 tgaaatacga cgaggtaatc aggggactta agaaaatggg gtttgaaatg aaacctaaaa
     6601 caggaacctc tcacgaacag tgggttctca agaacagtaa aggaaaatgg gtggttacag
     6661 ttgataagca tcacgcccca ttctccagag atttaataaa atccatggct aagcaagctg
     6721 gactgaaagc tcgtcacttt catgcgttat gcagaggtga cgcaacgctt gaggatatag
     6781 gattccaaat cattagctaa aacccggcct cagcgccggg ttttctttgc ctcacgcccc
     6841 cacctaaaga cacataacca aatgtattta ttgaaaaata aatagataca actcactaaa
     6901 ccacgcaatt ctgatctctc cttacatcgc cgaggcaata cacccacgct aaaaaacaac
     6961 actattaaat acaaagtgtt ataaaaaatc accccatttt agaacaaatc gtattgacac
     7021 aataaagtac atatcgtact atttaaccgt cagcaggacg ctggaagcca aacggaacag
     7081 actggcaggc tctttaaaca acgtcgaact ctcgactacg tggctgaaaa gccagatcac
     7141 ccaaccacat gagctgtggg atgcaatgcc gaagcaaccg tctcaggagg agcttcgaga
     7201 ttgcatcgcc aaagtttatt cgggaggaat ctatgtccag aaaaacagaa tttaaaggca
     7261 ccgcagcttc tcgccgtaga gctcgtcgcg caaatctgca aagtcagaag gcgatcagct
     7321 ccgacaagct acacaggcca accccttcac gagtggtctt gcaatgcaag cgcaaaccag
     7381 caatgagagc agaagtaata acactgacaa cgctgaccag aaaatatgaa ggctcaactt
     7441 gtcttccaaa cgtagctctt tacgcggcag gctaccggaa atccaaacaa ctgacagcaa
     7501 gatgacttgt gttggtcgcc agaaaatgaa attaggcagc aaaccactta tttgaggtga
     7561 gatatggaag aagaatttga agagttcgaa gatcatcctc aggatgtgat ggaacaatac
     7621 caggactatc cgtatgacta cgactattga taagaatcaa tggtgtagac aatacgaacg
     7681 acgacaatga ttgccagaga acttggtaaa cagaactaca aggctgcctg atggtggcct
     7741 ttatttttgt ccgtaaataa tttcatgctt attacaatca aggtgatata tggaagaaca
     7801 agcaaacaag attctcgtag aactactgca aaaagccagt aatggaatag acgcggctgt
     7861 ttcatttagc caggcacaga ttcctgatgt tgttcatcag ttgctgctat ggaatatggt
     7921 tgacagtctg attaaaacat taatggccat tctaacaatc ccactggttt tctggtttat
     7981 gaagaagcag tgccaaagag ttgagacagg taaaatcggt gatgaaggat attcatggga
     8041 gaaaggaaat cccaaataca ggccgacaat ggtttgggat agcaaaggtg atattaatct
     8101 tcttatcatg ccattggttg gagttttgac tctgtggggg atttttatta ttggtgtagt
     8161 aaccaatatg acttggttaa aaatttggct ggccccaaag ctttacctta tcgaatatgc
     8221 agcatcattg gttaagtaat ttcaggccgc atagtcggcc tttatttttg gcataaacaa
     8281 cagaataaac actgcactgt gtattcattc caacgagtga atacacggag caatgtcgct
     8341 cgtaactaaa caggagccga cttgttctga ttattggaaa tcttctttgc cctccagtgt
     8401 gaaggcgatt ttttatctat gaggatatga atagatgtca aacatcaaaa aatacatcat
     8461 tgattacgac tggaaagcat caatagaaat tgaaatcgac catgacgtaa tgacagagga
     8521 aaaacttcac cagattaata atttctggtc agactctgaa taccgactca ataaacacgg
     8581 ctctttatta aatgctgtat taatcatgct ggcgcaacat gctctgctta tagcaatttc
     8641 gaaagactta aatgcatatg gtgttgtttg tgagttcgac tgggatgatg gaaatggtca
     8701 ggaaggatgg cctccaatgg atggtagtga aggaataaga attaccgata tcgatacatc
     8761 aggaatattt gattcagatg atatgactat caaggccgcc tgagtgcggt tttaccgcat
     8821 accaataacg cttcactcga ggcgtttttc gttatgtata aataaggagc acaccatgca
     8881 atatgccatt gcagggtggc ctgttgctgg atgcccttcc gaatctttac ttgaacgaat
     8941 cacccgtaaa ttacgtgacg gatggaaacg ccttatcgac atgcttaatc agccaggagt
     9001 cccaaagaat ggatcaaaca cttatggcta tccagactaa attcactatc gccactttta
     9061 ttggcgatga aaagatgttt cgtgaagccg tcgacgctta taaaaaatgg atattaatac
     9121 tgaaactgag atcaagcaaa agcattcact aacccctttc ctgttttcct aatcagcccg
     9181 gcatttcgcg ggcgatattt tcacagctat ttcaggagtt cagccatgaa cgcttattac
     9241 attcaggatc gtcttgaggc tcagagctgg gcgcgtcact accagcagat cgcccgtgaa
     9301 gagaaagagg cagaactggc agacgacatg gaaaaaggcc tgccccagca cctgtttgaa
     9361 tcactctgca tcgatcattt acaacgccac ggggccagta aaaaagccat tacccgtgcg
     9421 tttgatgacg atgttgagtt tcaggagcgc atggcagaac acatccggta catggttgaa
     9481 accattgctc accaccaggt tgatattgat tcagaggtat aaaacggatg agtacagcac
     9541 tcgcaacgct ggctgggaag ctggctgaac gtgtcggcat ggattctgtc gacccacagg
     9601 aactgatcac cactcttcgc cagacggcat ttaaaggtga tgccagcgat gcgcagttca
     9661 tcgcattgtt gatcgtcgcc aaccagtacg gccttaatcc gtggacgaaa gaaatttacg
     9721 ccttccctga caagcagaac ggcatcgttc cggtggtggg cgttgatggc tggtcccgta
     9781 tcatcaatga aaaccagcaa tttgatggca tggactttga gcaggacaat gaatcatgta
     9841 catgccggat ttaccgcaag gaccgtaatc atccgatctg cgttaccgag tggatggatg
     9901 aatgccgccg cgaaccattc aaaactcgcg aaggcagaga aatcacgggg ccgtggcagt
     9961 cgcatcccaa acggatgtta cggcataaag ctatgattca gtgtgcccgt ctcgccttcg
    10021 gatttgctgg tatctatgac aaggatgaag ccgagcgcat tgtcgaaaat accgcataca
    10081 ctgcagaacg tcagccggaa cgcgacatca ctccggttaa cgatgaaacc atgcaggaga
    10141 ttaacactct gctgatcgcc ctggataaaa catgggatga cgacttattg ccgctctgtt
    10201 cccagatatt tcgccgcgac attcgcgcat cgtcagaact gacacaggcc gaagcagtga
    10261 aagctcttgg attcctgaaa cagaaagcca ctgagcagaa ggtggcagca tgataccgga
    10321 cattatcctg cagcgtaccg ggatcgacgt gagagctgtc gaacaggggg atgatgcatg
    10381 gcacaaatta cggctcggcg tcatcaccgc ttcagaagtt cacaacgtga tagcaaagcc
    10441 ccgctcagga aagaagtggc ctgacatgaa aatgtcctac ttccacaccc tgctggctga
    10501 ggtttgcacc ggtgtggctc cggaagttaa tgctaaggcg ctggcctggg gaaaacagta
    10561 cgagaacgac gccagaaccc tgtttgaatt cacttccggc gtgaatatta ctgaatcccc
    10621 gatcatctat cgcgacgaaa gtatgcgcac cgcctgctct cccgatggtt tatgcagtga
    10681 cggcaacggc ctggaactga aatgcccgtt tacctcccgg gatttcatga aattccggct
    10741 cggtggtttc gaggcaataa aatcggctta catggcccag gtgcagtaca gcatgtgggt
    10801 gacgcgaaaa gatgcctggt actttgccaa ctatgacccg cgtatgaagc gtgaaggcct
    10861 gcattatgtc gtggttgagc gggatgaaaa gtacatggcg agttttgacg agatggtgcc
    10921 ggagttcatc gaaaaaatgg acgaggcact ggctgaaatt ggttttgtat ttggggagca
    10981 atggcgatga agcatcctca cgataatatc cgggtaggtg cgatcacttt cgtctactcc
    11041 gttacaaagc gaggctgggt atttcccggc ctttctgtta tcagaaatcc cctgaaagca
    11101 cagcggctgg ctgaggagat aaataataaa cggggggctg tatgcacaaa gcatctcctg
    11161 ttgagttaag aacgtgtatc gagatggcac atagcctcgc tcaaattgga gtcaggtttg
    11221 tgccaatacc agtagaaaca gacgaagaat ttcatacgtt agccgcatcc ctttcacaaa
    11281 agctggaaat gatggtggcg aaagcagaag cagatgagag agaccaggta tgacaaccac
    11341 tgaatgcatt tttctggcag cgggcttcat attctgtgtg cttatgcttg ccgacatggg
    11401 acttgttcaa tgacacctca gcaagaaaac gcccttcgca gcattgcccg tcaggctaac
    11461 tctgaaatca aaaaagccag acagcagttt ccggataaaa acgtcgatga catttgccgt
    11521 agcgtactga agaagcaccg cgaaacggta acgctgatgg gattcacacc gactcattta
    11581 agtctggcga tcggcatgtt aaacggcgtc tttaaggagc gatgaacatg aaaagcaaaa
    11641 tcatcaggga gctacaggct ccttttttat tattcgcatt caccctcaag cgtattaacc
    11701 aacaattcag ggattaatga aagatggcag acataattga ttcagcatca gaaatcgaag
    11761 aattacagcg caatacagca ataaaaatgc gtcgtctgaa ctaccagact gtatctgcca
    11821 ctcattgttg tgagtgtggc gatccgatag atgagcgaag acgcctggct gttcagggtt
    11881 gtcggacttg tgcaagttgc caggaggaga tcgaacttaa gaacaaacaa tggggactgt
    11941 gatggcctca aagcagcaaa tttcaacatc gtccaactga ggtgtaaaaa tgttcagaat
    12001 catttttcct aacacctggt acgtcgacca ccacggtact ccctgcaaaa tcctgcgttc
    12061 tacccacaac aaagttcact acatccgaaa aggcagaaca tgtatcgcca gcatgttccg
    12121 ctttaatcat gactttgaac ctgtgaataa agctgatgca gatcggatag cagaagagat
    12181 cgaaacggca gaacacatta agaagttacg tgacatgcgt tcaaaaagca gaggtaacca
    12241 tggaatcata cagcctcaca ctcgatgagg cctgtcagtt tcttaagata tccagaccaa
    12301 ccgccaccaa ctggatacga acaggccgcc tacaggcaac acgtaaagat ccaaccaagc
    12361 caaaatctcc ttacctcaca acacggcaag cctgcattgc ggcgcttcag tctccgctgc
    12421 atactgtcca ggtgagcgcg ggtgatggca taacagagga aagaaaatgt cactcttccg
    12481 cagaaatgaa atatggtatg cctcgtattc gctcccgggc gggaaacgaa ttaaggaatc
    12541 tcttggcaca aaggacaagc ggcaagctca ggagttgcac gacaagcgaa aagcagaact
    12601 ctggcgagta gaaaagctag gggatttacc tgatgtcact tttgaagagg cctgcctaag
    12661 atggcttgag gaaaaagctg ataaaaaatc tctcgattca gataaaagcc ggattgagtt
    12721 ctggcttgaa cattttgagg gtataaggct taaagatatc tcggaggcaa agatttactc
    12781 tgctgtaagc agaatgcata acagaaagac gaaagaaata tggaaacaga aagttcaggc
    12841 cgccatcagg aaaggtaaag aaccgcctgt ttatgaacca aagccagtat caactcagac
    12901 aaaggcaaag catcttgcca tgataaaggc cattctccgt gctgcagaac gcgactggaa
    12961 gtggctggaa aaagcgcctg tcatcaagat accagcggtc agaaacaagc gagtcagatg
    13021 gctggaaaag gaggaagcaa aacgccttat tgatgagtgc cccgaaccac tgaaatctgt
    13081 cgtcaagttt gcgctggcaa ctggtctgag aaagtcgaac atcataaatc tggaatggca
    13141 acaaatcgac atgcagcgac gagttgcctg ggtgaatcca gaagagagca aatcaaaccg
    13201 cgccattggt gtggcgctga acgataccgc ctgtaaagtg ttgcgtgatc aaataggcaa
    13261 gcatcacaaa tgggtgtttg tacataccaa ggcggctaag cgagcagatg gaacatcaac
    13321 gcctgcggtc aggaagatgc gcatcgacag caagacatca tggctatcag cttgtcgtcg
    13381 tgcaggaatt gaagatttcc gtttccatga cctcagacac acctgggcaa gctggctgat
    13441 tcagtcaggc gtcccattat cagtgcttca ggaaatgggc ggatgggagt ccatagaaat
    13501 ggttcgtagg tatgctcacc ttgcgcctaa tcatttgaca gagcatgcga ggaaaataga
    13561 cgacattttt ggtgataatg tcccaaatat gtcccactct ggaattatgg aggatataaa
    13621 gaaggcgtaa ctgattgaat tgtaatggcg cgccctgcag gattcgaacc tgcggcccac
    13681 gacttagaag gtcgttgctc tatccaactg agctaagggc gcgttgatac cgcaatgcgg
    13741 tgtaatcgcg tgaattatac ggtcaaccct tgctgagtca atggcttttg atctggttgc
    13801 tgaacaagtg aacgaccgcg tctgattttc tgatttattt cgctatagcg gcaaacaaac
    13861 acacaccgct gcgcgtctga atcaagaaaa cccgtatttt catgtatcaa agtacaattt
    13921 accgccctaa cggaaaattg tccgctccta tgagactggt aactatgaaa ccaacgtcgg
    13981 tgatcattat ggatactcat cctatcatca gaatgtctat tgaagttctg ttgcaaaaaa
    14041 acagtgaatt gcagattgtc ctgaaaacgg atgattaccg cataaccatc gattatctcc
    14101 gaacccgtcc tgttgattta atcattatgg atatagactt gcccggaaca gacggtttta
    14161 ccttcctgaa aaggatcaaa caaatccaga gcacagtgaa agtgttattt ttatcatcga
    14221 aatcagaatg cttttatgct ggcagagcga tacaagctgg tgctaacggt tttgtcagta
    14281 aatgcaatga tcagaatgat atttttcatg ccgttcagat gatcctctcc ggatacacgt
    14341 tttttcccag cgaaacgctt aactatataa aaagcaataa atgtagtacg aatagttcaa
    14401 cggtcactgt gctatctaat cgtgaagtga ccatattacg ttatctggtt agcggattat
    14461 ctaataaaga aattgccgat aagttattac ttagcaataa aacagttagt gcgcataaat
    14521 ctaatattta tggcaagcta ggtttgcatt caattgtaga gctt
//
LOCUS       DAPGUL010000111        14444 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.113, whole genome shotgun sequence.
ACCESSION   DAPGUL010000111 DAPGUL010000000
VERSION     DAPGUL010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14444)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14444)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14444
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.113"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            252..1823
                     /gene="garD"
                     /locus_tag="RHX21_003642"
     CDS             252..1823
                     /gene="garD"
                     /locus_tag="RHX21_003642"
                     /EC_number="4.2.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate dehydratase"
                     /protein_id="HDV1988768.1"
                     /translation="MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLE
                     LIEHIPQGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTL
                     PLATKVPAPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDL
                     LPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKL
                     QPERLLVGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQVAERHLQKLNQRQRET
                     CPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTP
                     RAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGK
                     SAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVP
                     VIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQW
                     GLHNQLAVFNPAPVT"
     gene            1972..2307
                     /gene="prlF"
                     /locus_tag="RHX21_003643"
     CDS             1972..2307
                     /gene="prlF"
                     /locus_tag="RHX21_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PrlF"
                     /protein_id="HDV1988769.1"
                     /translation="MPANARSHAVLTTESKVTIRGQTTIPAPVREALKLKPGQDSIHY
                     EILPGGQVFMCRLGDEQEDHTMNAFLRFLDADIQNNPQKTRPFNIQQGKKLVAGMDVN
                     IDDEIGDDE"
     gene            2307..2771
                     /gene="yhaV"
                     /locus_tag="RHX21_003644"
     CDS             2307..2771
                     /gene="yhaV"
                     /locus_tag="RHX21_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system ribonuclease
                     toxin YhaV"
                     /protein_id="HDV1988770.1"
                     /translation="MDFPQRVNGWALYAHPCFQETYDALVAEVETLKGKDPENYQRKA
                     ATKLLAVVHKVIEEHITVNPSSPAFRHGKSLGSGKNKDWSRVKFGAGRYRFFFRYSEK
                     EKVIILGWMNDENTLRTYGKKTDAYTVFSKMLKRGHPPADWESLTQETEENH"
     gene            complement(2826..3635)
                     /gene="agaR"
                     /locus_tag="RHX21_003645"
     CDS             complement(2826..3635)
                     /gene="agaR"
                     /locus_tag="RHX21_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aga operon transcriptional regulator AgaR"
                     /protein_id="HDV1988771.1"
                     /translation="MSNTDASGEKRVTGTSERREQIIQRLRQQGSVQVNDLSALYGVS
                     TVTIRNDLAFLEKQGIAVRAYGGALICDSTTPSVEPSVEDKSALNTAMKRSVAKAAVE
                     LIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLR
                     RQSQSFYGDQAEQSLQNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERII
                     VVTDSSKFNRSSLHKIIDTQRIDMIIVDEGIPADSLEGLRKAGVEVILVGE"
     gene            3884..5164
                     /gene="kbaZ"
                     /locus_tag="RHX21_003646"
     CDS             3884..5164
                     /gene="kbaZ"
                     /locus_tag="RHX21_003646"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit KbaZ"
                     /protein_id="HDV1988772.1"
                     /translation="MKHLTEMVRQHKAGKTNGIYAVCSAHPLVLEAAIRYASANQTPL
                     LIEATSNQVDQFGGYTGMTPADFRGFVCQLADSLNFPQDALILGGDHLGPNRWQNLPA
                     AQAMANADDLIKSYVAAGFKKIHLDCSMSCQDDPIPLTDDIVAERAARLAKVAEETCL
                     EHFGEADLEYVIGTEVPVPGGAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWP
                     RIIALVVQPGVEFDHTNVIDYQPAKASALSQMVENYETLIFEAHSTDYQTPQSLRQLV
                     IDHFAILKVGPALTFALREALFSLAAIEEELVPAKACSGLRQVLEDVMLDRPEYWQSH
                     YHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFAHLVRNLADSPIPLPLISQYLPLQY
                     VKVRSGELQPTPRELIINHIQDILAQYYTACEGQ"
     gene            5187..5660
                     /gene="agaV"
                     /locus_tag="RHX21_003647"
     CDS             5187..5660
                     /gene="agaV"
                     /locus_tag="RHX21_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312038.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIB"
                     /protein_id="HDV1988773.1"
                     /translation="MPNIVLSRIDERLIHGQVGVQWVGFAGANLVLVANDEVAEDPVQ
                     QNLMEMVLAEGIAVRFWTLQKVIDNIHRAADRQKILLVCKTPADFLTLVKGGVPVNRI
                     NVGNMHYANGKQQIAKTVSVDAGDIAAFNDLKAAGVECFVQGVPTEPAVDLFKLL"
     gene            5671..6450
                     /locus_tag="RHX21_003648"
     CDS             5671..6450
                     /locus_tag="RHX21_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HDV1988774.1"
                     /translation="MEISLLQAFALGIIAFIAGLDMFNGLTHMHRPVVLGPLVGLVLG
                     DLHTGILTGGTLELVWMGLAPLAGAQPPNVIIGTIVGTAFAITTGVKPDVAVGVAVPF
                     AVAVQMGITFLFSVMSGVMSRCDRMAENADTRGIERVNYLALLALGTFYFLCAFLPIY
                     FGAEHAKTIIDVLPQRLIDGLGVAGGIMPAIGFAVLLKIMMKNVYIPYFILGFVAAAW
                     LKLPVLAIAAAALAMALIDLLRKSPEPTQPAAQKEEFEDGI"
     gene            6440..7318
                     /locus_tag="RHX21_003649"
     CDS             6440..7318
                     /locus_tag="RHX21_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019079236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HDV1988775.1"
                     /translation="MASNQTTLPNVSENEETLLTGVNENVYEDQSIGAELTKKDINRV
                     AWRSMLLQASFNYERMQASGWLYGLLPALKKIHTNKRDLARAMKGHMGFFNTHPFLVT
                     FVIGIILAMERSKQDVNSIQSTKIAVGAPLGGIGDAMFWLTLLPICGGIGASLALQGS
                     ILGAVVFILLFNVVHLGLRFGLAHYAYRMGVAAIPLIKANTKKVGHAASIVGMTVIGA
                     LVATYVRLSTTLEITAGDAVVKLQTDVIDKLMPAFLPLVYTLTMFWLVRRGWSPLRLI
                     AVTVVLGIVGKFCHFL"
     gene            7336..7770
                     /locus_tag="RHX21_003650"
     CDS             7336..7770
                     /locus_tag="RHX21_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDV1988776.1"
                     /translation="MLSIILTGHGGFASGMEKAMKQILGEQSQFIAIDFPETSSTALL
                     TSQLEEAIAQLDCEDGIVFLTDLLGGTPFRVASTLAMQKPGCEVITGTNLQLLLEMVL
                     EREGLSGEEFRVQALECGHRGLTSLVDELGRCHEECPVEEGI"
     gene            7767..8900
                     /gene="nagA"
                     /locus_tag="RHX21_003651"
     CDS             7767..8900
                     /gene="nagA"
                     /locus_tag="RHX21_003651"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDV1988777.1"
                     /translation="MTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPVGVTERDA
                     ELLCPAYIDTHVHGGAGVDVMDDAPDVLDKLAMHKAREGVGSWLPTTVTAPLNSIHAA
                     LKRIAQRCQRGGPGAQVLGSYLEGPYFTPQNKGAHPPELFRELEIAELDQLIAVSQHT
                     LRVVALAPEKEGALQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMT
                     GLHHREPGMVGAGLTDKRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGM
                     PDGRYTLCGEEVQMHGGVVRTASGGLAGSTLSVDAAVRNMVELTGVTPAEAIHMASLH
                     PARMLGVDGVLGSLKPGKRASIVALDSGLHVQQIWIQSQLASF"
     gene            9250..10404
                     /locus_tag="RHX21_003652"
     CDS             9250..10404
                     /locus_tag="RHX21_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AgaS family sugar isomerase"
                     /protein_id="HDV1988778.1"
                     /translation="MPENYTPAAAATGTWTEEEIRHQPRAWIRSLTNIDALRSALNNF
                     LEPLLRKENLRIILTGAGTSAFIGDIIAPWLASHTGKNFSAVPTTDLVTNPMDYLNPA
                     HPLLLISFGRSGNSPESVAAVELANQFVPECYHLPITCNEAGALYQNAINSDNAFALL
                     MPAETHDRGFAMTSSITTMMASCLAVFAPETINSQTFRDVADRCQAILTSLGDFSEGV
                     FGYAPWKRIVYLGSGGLQGAARESALKVLELTAGKLAAFYDSPTGFRHGPKSLVDDET
                     LVVVFVSSHPYTRQYDLDLLAELRRDNQAMRVIAIAAESSDIVAAGPHIILPPSRHFI
                     DVEQAFCFLMYAQTFALMQSLHMGNTPDTPSASGTVNRVVQGVIIHPWQA"
     gene            10417..11277
                     /gene="kbaY"
                     /locus_tag="RHX21_003653"
     CDS             10417..11277
                     /gene="kbaY"
                     /locus_tag="RHX21_003653"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit KbaY"
                     /protein_id="HDV1988779.1"
                     /translation="MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSP
                     VILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALHLDHHESLDDIRRKVHAGVRSAM
                     IDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEA
                     KRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFV
                     RRTIELGVTKVNVATELKIAFAGAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKIN
                     VCGSANRISA"
     gene            11444..11920
                     /gene="agaB"
                     /locus_tag="RHX21_003654"
     CDS             11444..11920
                     /gene="agaB"
                     /locus_tag="RHX21_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIB"
                     /protein_id="HDV1988780.1"
                     /translation="MSSPNILLTRIDNRLVHGQVGVTWTSTIGANLLVVVDDVVANDD
                     IQQKLMGITAETYGFGIRFFTIEKTINVIGKAAPHQKIFLICRTPQTVRKLVEGGIDL
                     KDINVGNMHFSEGKKQISSKVYVDDQDLADLRFIKQRGVNVFIQDVPGDQKEQIPD"
     gene            11959..12762
                     /gene="agaC"
                     /locus_tag="RHX21_003655"
     CDS             11959..12762
                     /gene="agaC"
                     /locus_tag="RHX21_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIC"
                     /protein_id="HDV1988781.1"
                     /translation="MHEITLLQGLSLAALVFVLGIDFWLEALFLFRPIIVCTLTGAIL
                     GDIQTGLITGGLTELAFAGLTPAGGVQPPNPIMAGLMTTVIAWSTGVDAKTAIGLGLP
                     FSLLMQYVILFFYSAFSLFMTKADKCAKEADTAAFSRLNWTTMLIVASAYAVIAFLCT
                     YLAQGAMQALVKAMPAWLTHGFEVAGGILPAVGFGLLLRVMFKAQYIPYLIAGFLFVC
                     YIQVSNLLPVAVLGAGFAVYEFFNAKSRQQAQPQPVASKNEEEDYSNGI"
     gene            12752..13543
                     /gene="agaD"
                     /locus_tag="RHX21_003656"
     CDS             12752..13543
                     /gene="agaD"
                     /locus_tag="RHX21_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708938.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IID"
                     /protein_id="HDV1988782.1"
                     /translation="MGSEISKKDITRLGFRSSLLQASFNYERMQAGGFTWAMLPILKK
                     IYKDDKPGLSAAMKDNLEFINTHPNLVGFLMGLLISMEEKGENRDTIKGLKVALFGPI
                     AGIGDAIFWFTLLPIMAGICSSFASQGNLLGPILFFAVYLLIFFLRVGWTHVGYSVGV
                     KAIDKVRENSQMIARSATILGITVIGGLIASYVHINVVTSFAIDSTHSVALQQDFFDK
                     VFPNILPMAYTLLMYYFLRVKKAHPVLLIGVTFVLSIVCSAFGIL"
     gene            13544..14299
                     /locus_tag="RHX21_003657"
     CDS             13544..14299
                     /locus_tag="RHX21_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosamine-6-phosphate isomerase"
                     /protein_id="HDV1988783.1"
                     /translation="MERGTASGGASLLKEFHPVQTLQQVENYTALSERASEYLLAVIR
                     SKPDAVICLATGATPLLTYHYLVEKIHQQQVDISQLTFVKLDEWVDLPLTMPGTCETF
                     LQQHIVQPLGLREDQLISFRSEEINETECERVTNLIARKGGLDLCVLGLGKNGHLGLN
                     EPGESLQPACHISQLDARTQQHEMLKTTGRPVTRGITLGLKDILNAREVLLLVTGEGK
                     QDATERFLTAKVSTAIPASFLWLHSNFICLINT"
BASE COUNT         3517 a         3635 c         3747 g         3545 t
ORIGIN      
        1 tcattgtgca aatgctaatt taattaatac tatttaaata ttattttgag catatgcaca
       61 taaggttgcg cgctaaagca cagatttgcg ctttaccttg ccgggcggca ctgcaatccc
      121 tgaaatgatt gacattgatc acatttctgc gtttaaactc ctgacattct tatttcaccc
      181 aatgaagtca tttattttta aatgagacca ggtcctcatt ttaataaccc ctggctggag
      241 aatattgcac aatggccaac atcgaaatca gacaagaaac gccaactgcg ttttatataa
      301 aagttcacga cacagataat gtggcaatta ttgttaatga taatggcctg aaagcaggaa
      361 cgcgttttcc ggatgggctg gaattaattg aacatattcc ccaggggcat aaagtcgcat
      421 tgctggacat tccggctaat ggtgaaatta ttcgttatgg cgaagtgatt ggttacgccg
      481 tgcgtgcaat cccacgcgga agctggatcg acgaatcaat ggttgtacta ccggaagcgc
      541 cgccgttaca cacgctgcca ctggcaacca aagtcccggc ccccttaccg ccgctggaag
      601 gatacacctt tgagggctat cgcaatgccg atggcagcgt gggcaccaaa aacctgctcg
      661 gcatcaccac cagcgtccac tgtgtggcag gcgtggtgga ctatgtagta aaaatcattg
      721 aacgcgatct gctaccgaaa tacccgaacg tcgatggcgt ggtggggctg aatcatttgt
      781 acggctgtgg cgtggcgatt aacgcaccgg cggcagttgt gcctattcgt accatccaca
      841 atatttcgct gaaccctaac tttggcggcg aagtaatggt gattggtctg ggttgtgaaa
      901 agttgcagcc tgagcgcctg ctggtcggca cggatgatgt gcaagctatt ccagtagaaa
      961 gcgccagcat tgtcagtttg caggatgaaa agcatgtcgg ttttcagtcc atggtcgagg
     1021 atattttgca ggtcgccgaa cgccatctac aaaaactgaa tcaacgtcag cgagaaacct
     1081 gtccggcttc agaactggtt gtcggcatgc agtgcggtgg cagcgatgcc ttttctggcg
     1141 taacggcaaa cccggcggtt ggctatgcgt ctgatctact ggtgcgctgc ggcgcaacgg
     1201 tgatgttctc agaagtcacg gaagtgcgtg acgcgatcca tctgctgaca ccacgcgcag
     1261 tgaacgaaga ggtcggcaaa cggctgctgg aggagatgga gtggtacgat aactatctca
     1321 atatgggaaa aaccgaccgc agcgccaacc cttcgccggg caacaagaaa ggcggtctgg
     1381 caaacgtggt agagaaggca ctcggctcca ttgctaaatc gggtaaaagc gcaattgttg
     1441 aagtgctgtc gcccggtcaa cgcccgacta aacgcggatt aatttacgcc gcgacgccag
     1501 ccagcgattt tgtctgtggc acgcaacagg tggcttcggg tatcaccgtg caagtgttta
     1561 cgaccggtcg tggtacgccg tacggcctga tggcggtacc cgtcattaaa atggcgaccc
     1621 gcaccgagct ggcgaaccgc tggtttgatt taatggatat taacgcgggc actatcgcca
     1681 ccggcgaaga aaccattgaa gaggtgggct ggaagttgtt ccactttatt ctcgacgtcg
     1741 ccagcgggaa gaagaaaacc ttctcggatc aatgggggct gcataaccag ctggcagtgt
     1801 ttaacccggc accggtgacc tgatttcttt tggaacgtcc ctcgcaaaac atggccttag
     1861 tgccatgttt ttattgttta aagcccccac gtccattaat aatgcatttg cattacctta
     1921 gttcaagctt ataatttgag cagaaaacag gctgtaaaag gacagtgaat catgcccgct
     1981 aatgctcgct ctcacgctgt actgaccact gaatcaaagg tcacgatacg cggacaaaca
     2041 actatccccg cgccagtgcg tgaggcctta aaactgaagc caggccagga cagcattcat
     2101 tacgaaattc tgcctggtgg gcaagtcttt atgtgccgac tgggagatga acaggaggat
     2161 catactatga atgcattttt gcgttttctg gatgcagata tccagaacaa cccgcaaaaa
     2221 actcgtccat tcaacattca acaaggaaag aaacttgtcg ctggcatgga cgtcaacatt
     2281 gatgatgaga ttggcgacga cgaataatgg attttccaca aagggttaat ggttgggcgc
     2341 tatatgctca tccctgtttt caggaaacct acgacgcttt agttgccgaa gtcgagacat
     2401 taaagggaaa agatcctgaa aattatcaga gaaaagccgc cacaaagtta ttggcggtag
     2461 tccataaagt gattgaggag catatcacgg tcaatccatc atcaccggca ttccgtcatg
     2521 gcaagtcgtt aggctctggg aaaaataaag actggtcacg ggtaaaattt ggtgctggtc
     2581 gttatcgttt cttctttcgt tatagtgaaa aagagaaagt catcattctg ggatggatga
     2641 acgatgaaaa cactctgcgc acctacggta aaaaaacaga tgcctatacc gtattcagca
     2701 aaatgttaaa aagaggacat cctcctgccg actgggaaag cctcacccaa gagacagaag
     2761 aaaaccattg atggtgttca caatgcccgc cgaacgtatt cgtgttgacc agcgggcacc
     2821 ctttctcact ccccgaccag aatcacttca accccagcct ttcgcagtcc ttccagacta
     2881 tccgcaggaa tgccttcatc aacaatgatc atgtcgatac gttgagtatc aatgatctta
     2941 tgtaaactgg aacgattgaa tttactggaa tcggtgacca cgatgatccg ttccgcaact
     3001 tcgcacatcc gacggtttaa acgggcttca tcttcattat gtgtgctgac gccgcgctcc
     3061 agatcgatcg catctacacc aagaaacagc atatcgaagt ggtaattttg cagcgattgc
     3121 tcagcctgat cgccgtaaaa agattgcgac tgacggcgca aatgcccgcc ggtcatcagc
     3181 agctcaacgc cttccgcttc cagcaacgca ttagccacgt tcataccgtt ggtcatcgca
     3241 attacgtcag tgtgcttacg catcagacga gcaatctcaa aagtggtagt cccggaatcg
     3301 aggatcaccc gatgaccagg ctgaatcaac tcaacggcag ctttcgcaac gctgcgtttc
     3361 atcgcggtgt tcagcgcgct tttatcttcc actgatggct cgactgacgg cgtcgtgcta
     3421 tcgcagatca acgcgccacc ataggcacgc acagcgatcc cctgcttttc cagaaacgcc
     3481 agatcattgc ggatcgtcac agtagatacg ccatacaatg ccgacagatc gttaacctgc
     3541 acactccctt gctgtcgcag acgctgaatg atctgttctc gtcgctcgct ggtgccagtc
     3601 actcgcttct cacctgaagc gtcggtatta ctcatagtaa gtcctttcgt aaaactttcg
     3661 tttcatttcg ttttgcctat taacgccttt ctattaagca aatgcaagcc caccttgccc
     3721 attggcgcaa gctactctcg tttcagtgac tttcattatg tttcttttgt gaatcagatc
     3781 agaaaactat tatctttcgt tttattttta tctcaccatg acgcagtatc aactgaaaca
     3841 aaacgaaaga ttaatatcgc agtaatctga actggagagg aaagtgaaac atctgacaga
     3901 aatggtgaga cagcacaaag cgggcaaaac aaatggaatt tatgccgttt gttccgcaca
     3961 tccgctggtg ctggaggctg caatccgcta cgccagtgca aaccaaacgc cgttactgat
     4021 tgaagcaacc tccaatcagg tagaccagtt cggcggttat accggaatga cgcccgccga
     4081 ttttcgcggc tttgtttgtc agctcgccga ctcgttgaat ttcccgcagg atgcgttgat
     4141 tctgggtggt gaccatctgg ggccaaaccg ctggcaaaac ctgccggccg ctcaggcaat
     4201 ggccaatgcc gatgatttga ttaaaagcta cgttgcggca ggattcaaaa aaatccacct
     4261 tgattgcagc atgtcctgtc aggacgatcc gattccctta actgatgaca tcgtggctga
     4321 acgcgccgcc cgtctggcga aagtggcgga agaaacctgt cttgaacact ttggcgaagc
     4381 cgatctggag tatgtcattg gtaccgaagt gccggtacct ggcggcgcgc atgaaacctt
     4441 aagcgagctg gcggtcacca cgccggatgc cgcccgcgcc acgctggaag cccatcgtca
     4501 cgcctttgaa aagcaaggtt tgaatgccat ctggccacgc atcattgccc tggtggttca
     4561 acccggcgtc gaattcgatc acaccaacgt tattgattat cagcccgcca aagcgagcgc
     4621 cttaagccag atggtcgaaa actacgaaac gctgattttc gaagcgcact ctaccgatta
     4681 tcaaacgccg caatcgctgc gccagctggt gattgaccac tttgccattc tgaaagttgg
     4741 cccagcgctg accttcgccc tgcgtgaagc tctgttctct ctggcggcga ttgaagaaga
     4801 actggtgcca gcgaaagcct gttctggtct gcgtcaggtg ctggaagacg tgatgctcga
     4861 ccgcccggaa tactggcaaa gccactacca cggtgacggc aacgcgcgtc gtctggcgcg
     4921 tggttatagc tactcggatc gcgtgcgcta ttactggccg gacagccaga ttgatgacgc
     4981 tttcgctcat ctggttcgta atctggcgga ttcaccaatt ccgctaccgc tcatcagcca
     5041 gtatctgccg ctgcaatacg tgaaagttcg ctccggcgag ctgcaaccga cgccacggga
     5101 actcattatc aaccatattc aggacatcct ggcgcagtac tacacagcct gtgaaggcca
     5161 ataagcaaaa caaagaggaa cacgctatgc caaatattgt tttaagccgg attgatgaac
     5221 gcttgattca cggtcaggtc ggcgttcagt gggtcggatt tgcgggggca aatctggtgc
     5281 tggtagccaa cgatgaggtt gccgaagatc cggtacaaca aaacctgatg gaaatggtac
     5341 tggcagaagg gatcgccgta cgtttctgga cgctgcaaaa agttatcgac aacattcatc
     5401 gcgccgccga tcgacagaaa atcctgctgg tttgtaaaac acccgccgat ttcctgacgc
     5461 tggtgaaagg tggcgttccg gtgaatcgca ttaacgttgg caatatgcac tacgccaatg
     5521 gcaaacaaca aatcgccaaa acggtttctg tggatgcggg cgatatcgca gcatttaacg
     5581 acctgaaagc cgctggggtg gaatgcttcg ttcagggcgt cccgacagag cctgctgtgg
     5641 acctctttaa attactttga gggattcatc atggaaatca gcctgttgca ggcatttgcg
     5701 ttgggcatta tcgcctttat cgctggcctg gatatgttta acggcctaac acatatgcac
     5761 cgcccggtgg tcctcggccc gttggtcggg ctggtacttg gcgatctgca taccggaatt
     5821 ttaaccggcg gtacgctgga actggtgtgg atggggctgg ccccgctggc gggcgcacag
     5881 ccgcctaacg tgattatcgg tactatcgtc ggcacggcgt ttgccattac tactggcgtg
     5941 aaacccgatg tcgcggtcgg tgtcgccgta cctttcgctg tcgcagtaca gatggggatt
     6001 accttcctgt tctcggtgat gtctggcgtg atgtctcgct gcgaccggat ggcggagaac
     6061 gccgatactc gcggcattga acgcgtgaac tatctggcac tgctggcact cggcactttc
     6121 tattttctct gcgctttcct gcctatctac ttcggcgcgg aacatgcaaa aaccatcatt
     6181 gatgtcctgc cgcaacgatt aatcgacggc ctcggcgtcg cgggcggcat catgccagca
     6241 atcggttttg ccgtgctgct gaaaatcatg atgaaaaacg tctacatccc ctacttcatc
     6301 ctgggctttg ttgccgcagc ctggctcaag ttaccggtgc tggctattgc tgccgctgcg
     6361 ctggcgatgg cgctgatcga cctgctgcgt aaatctcctg aaccgactca acctgcggca
     6421 cagaaagagg aatttgaaga tggcatctaa tcaaaccacc ctgccgaacg tcagtgaaaa
     6481 cgaagaaaca ttgctgactg gcgtcaatga aaacgtgtat gaagatcaga gcattggcgc
     6541 ggagctgacg aaaaaagata tcaaccgcgt cgcctggcgt tccatgctgt tacaagcgtc
     6601 ttttaactac gaacgtatgc aggcttctgg ctggttgtac ggtctgctgc ctgctctgaa
     6661 aaagatccac actaataaac gcgacctggc gcgcgccatg aaggggcata tgggtttctt
     6721 caatacccat ccgtttctgg tgacatttgt tatcggcatt atccttgcga tggagcgttc
     6781 taagcaggac gttaacagta ttcagagcac caaaattgcc gtcggtgcgc cgctcggcgg
     6841 gattggcgat gcaatgttct ggctaacgct actgccgatt tgtggcggga ttggagccag
     6901 tctggcattg caaggctcca ttcttggcgc agtcgtcttt attctgctgt tcaacgtggt
     6961 acacctgggg ctgcgttttg gtctggcgca ttatgcttac cgcatgggcg tggcggcgat
     7021 tccactcatt aaagcgaata ccaaaaaagt cggccatgct gcgtctatcg ttgggatgac
     7081 ggtaatcggc gcgctggtgg caacctatgt tcgtttaagc accacgctgg aaatcacagc
     7141 gggcgacgca gtggttaagt tacagactga tgttattgac aaactgatgc ctgccttctt
     7201 accgctggtc tacaccttga ccatgttctg gctggtacgc cgcggctgga gtccgctgcg
     7261 tctgattgca gttaccgtgg ttctcggcat cgtcggtaaa ttctgccatt tcctttaaat
     7321 acaatgaggt attagatgtt aagtattatt ttgacagggc atggcgggtt tgccagcggc
     7381 atggaaaaag caatgaagca aattctcggt gagcaatcgc agtttatcgc catcgatttt
     7441 ccggaaacct caagcaccgc gctgcttaca tcgcagcttg aagaggccat cgcccaactg
     7501 gattgtgaag acggcattgt ttttctgacg gatttgctgg gcggcacgcc gtttcgcgta
     7561 gcttcaacgc tggcgatgca aaaaccgggc tgtgaagtga tcaccggcac caatttgcaa
     7621 ctgctactgg agatggtgct ggagcgcgaa gggttaagcg gtgaagaatt ccgtgtacag
     7681 gcgctggagt gtggacaccg agggctgacc agtctggtgg acgagttagg ccgctgccat
     7741 gaagaatgtc cggtcgagga aggaatatga cacacgttct gcgcgccaga aggctgctga
     7801 ctgaagaggg atggctcgat gaccatcagt tgcgtattgc tgacggtgtc atcgcagcaa
     7861 tcgaaccgat tccagtgggc gtgactgaac gcgatgcgga actgctctgc cccgcttaca
     7921 tcgacaccca tgtacacggt ggtgcgggcg ttgatgtaat ggatgacgcg ccggatgtac
     7981 tcgacaagct ggcaatgcac aaggcacgcg aaggtgtcgg cagttggttg ccgactaccg
     8041 taaccgcgcc gcttaacagc attcatgcgg cgctgaaacg tattgctcaa cgttgccaac
     8101 gcggcggacc tggtgcgcaa gtgctgggga gttatctcga aggaccgtac ttcacgccgc
     8161 agaataaagg cgcgcatccg ccggaattgt ttcgcgagct tgaaattgcc gagctggatc
     8221 aattgattgc cgtttctcag cacaccttac gcgtggtagc gctggcaccg gaaaaagagg
     8281 gggcattgca ggccatccgc catcttaaac agcaaaatgt acgagtgatg ctggggcata
     8341 gcgcggcgac ctggcaacaa actcgcgccg cgtttgatgc tggtgccgac ggcctggtgc
     8401 attgctataa cgggatgaca ggtttacatc accgcgaacc gggaatggtt ggcgcgggat
     8461 taacggacaa gcgcgcctgg ctggaactga tagccgatgg tcatcatgtg catccggcgg
     8521 cgatgtcgct gtgttgttgc tgtgcaaaag agagaatcgt gctgatcacc gacgcgatgc
     8581 aggcagccgg gatgccggat ggtcgctata cgttatgtgg cgaagaagtg cagatgcacg
     8641 gtggcgttgt ccgtaccgcg tccggtgggc tggcgggcag tacgctgtct gttgatgcgg
     8701 cagtgcgcaa catggtcgag ttgacgggcg taacgcctgc ggaagccatt catatggcat
     8761 cgctgcatcc ggcgcgaatg ctgggtgttg atggtgttct gggatcgctt aaaccgggca
     8821 aacgcgccag catcgttgcg ctggatagcg ggctgcatgt gcaacaaatc tggattcaga
     8881 gtcaattagc ttcgttttga tagtttgctc ctttattggg ccttcacttc ccccgtaagg
     8941 cctttctttt tctttcgttt tgatctgtgc agcggtgtcg gatgcgacgc taacgcgtct
     9001 tatgcgacct acggtacgcc gcatccggca atcggtgaac atagcgacgt cattacgcaa
     9061 ttcttaatct tcccttgtct tttctttcaa cgatcacaga tttcgtttta tttccttttt
     9121 cttcattgaa ctttcagttt cttttctata gattttaatc aacgaaagac atcaccaagt
     9181 gaaatgaaac gaaaggcaag tgaaagcgac aacgcccgac gtcaagttca tcagactaag
     9241 gattgagtta tgccagaaaa ttacacccct gctgccgccg caaccggtac atggactgaa
     9301 gaagagatcc gccatcagcc tcgcgcatgg atccgttcac tcaccaacat cgacgcgcta
     9361 cgttccgcgc tcaataactt ccttgaaccg ttactgcgca aagagaatct gcggatcatc
     9421 ctgaccggag ccggaacgtc ggcatttatc ggtgacatca tcgcgccgtg gctcgccagc
     9481 cataccggta aaaacttcag cgccgtaccg accaccgatc tggtcaccaa tccgatggac
     9541 tacctgaatc cagctcatcc gctgctgttg atctccttcg gtcgatccgg caacagcccg
     9601 gaaagcgtcg ctgccgtgga actggcaaat caatttgtac cggaatgcta tcacctgccg
     9661 atcacctgca acgaagcggg cgctctttac caaaacgcga tcaacagcga taacgcattt
     9721 gccctgctga tgcccgcaga aacgcacgat cgcggctttg cgatgaccag cagcattacc
     9781 accatgatgg ccagctgcct cgcggttttc gcacctgaga cgatcaacag ccaaaccttc
     9841 cgcgacgtgg cggatcgttg ccaggcgatc ctgacctcac tgggcgattt cagcgaaggt
     9901 gtgtttggtt acgcaccgtg gaaacggatc gtttatctcg gcagcggtgg cttacagggc
     9961 gcagcacgcg agtcggcgct gaaagtgctg gaactgacgg cgggtaaact ggcggccttt
    10021 tatgattctc caaccggatt ccgtcatgga ccaaaatcgc tggtcgatga cgaaacgctg
    10081 gtggtggtat ttgtctccag ccacccttac acccgtcagt atgatcttga tctgctggct
    10141 gaacttcgcc gtgacaacca ggcaatgcgt gtaatcgcca tcgccgcgga aagcagcgac
    10201 atcgtcgctg ccggtccaca tatcatcctg ccaccgtcac gtcactttat cgacgttgag
    10261 caggcatttt gcttcctgat gtacgcccag acgtttgcac tgatgcagtc gctgcacatg
    10321 ggcaatacgc cggatacccc atcagccagt ggcaccgtta accgcgtggt gcaaggcgta
    10381 atcattcatc cgtggcaggc ataagaggat cgcattatga gcattatctc cactaaatat
    10441 ctgttacagg acgcccaggc caatggctac gcggtgcctg cttttaacat tcataacgcc
    10501 gagacgatcc aagcgatcct cgaagtgtgc agtgaaatgc gatcgccggt gatcctcgcc
    10561 ggaacgccgg ggacctttaa acatatcgcg ctggaagaga tctacgccct gtgcagcgcc
    10621 tattccacaa cctacaacat gccactggcg ctgcatctcg accaccacga atcgctggat
    10681 gatattcgcc gtaaagtcca cgcaggtgtg cgcagtgcaa tgatcgacgg cagccacttc
    10741 ccgtttgccg agaacgtgaa gctggtgaaa tcggttgttg acttctgcca ctcacaggat
    10801 tgcagcgtgg aagcagaact gggccgcctg ggcggtgttg aagatgacat gagcgttgac
    10861 gccgaaagtg cattcctgac cgatccacaa gaagctaaac gctttgtcga actgactggc
    10921 gtcgacagcc tggcggtagc gattggtacg gcgcacggct tatacagcaa aacgccgaag
    10981 attgatttcc agcggctggc ggaaattcgt gaagtggtgg atgttcctct ggtgctacat
    11041 ggtgccagcg atgttccaga tgaatttgtc cgtcgcacta ttgaacttgg cgtcacaaaa
    11101 gtgaacgttg ccacagaatt aaaaatagcc ttcgctggcg cggttaaagc ctggtttgcg
    11161 gaaaatccgc agggtaatga tcctcgttat tatatgcgcg tcggaatgga tgcgatgaaa
    11221 gaagttgtca gaaataaaat taatgtctgt ggttcagcga atcgaatttc agcataatca
    11281 ttagtttttt atgatttatc ccaatgtact tcccgattaa tatcggggag tgccttaatg
    11341 gaaaaggaga tgactaaacc ttaataaata catcagtaca atatcgcaac aataatatat
    11401 taaaaaaaat catattattc aactttatgg tgaggattac acaatgagca gtccaaatat
    11461 tctcttaacc cgtattgata accgtctggt tcacggtcag gttggcgtga cctggacatc
    11521 caccatcggt gcgaatctgc tggtagtcgt ggatgatgtt gtcgctaacg atgatattca
    11581 acagaaatta atgggtatta ccgcagaaac ctacggcttt ggcattcgtt tctttactat
    11641 cgaaaaaacc attaacgtca tcggcaaagc tgcaccgcat cagaagatct tcctgatttg
    11701 ccgtacgcca caaacggtac gtaaattggt agaaggtggc attgacctga aagatatcaa
    11761 cgtcggcaat atgcatttct cggaagggaa aaagcaaatc agcagtaaag tttatgtcga
    11821 tgaccaggat ctcgcggact tacgttttat taaacaacgt ggcgtgaatg ttttcattca
    11881 ggacgtccct ggcgatcaaa aagaacaaat ccctgactaa atctaaaatc gccttaatat
    11941 tggtttgagg taataaaaat gcatgaaata accctacttc agggattatc cctggcggcg
    12001 ttagttttcg ttctggggat tgatttttgg ctggaagcct tatttttatt ccgcccgata
    12061 atcgtttgta ccctaactgg cgctattctc ggtgatattc agactggctt aattaccggt
    12121 ggtctgacag agttggcttt cgccggatta acccctgcag gtggtgttca gccgcccaac
    12181 ccgattatgg cgggtctgat gaccaccgtc attgcatggt ctacgggcgt tgatgccaaa
    12241 acagcaattg gtcttggcct gccgtttagt ttgttaatgc agtacgtcat tctgttcttc
    12301 tattccgctt tctcattatt tatgaccaaa gccgataaat gcgcgaaaga ggcggatacg
    12361 gcagcgtttt cccggcttaa ctggacaacg atgctcatcg tcgcttcagc gtatgcggtg
    12421 attgctttcc tctgtactta cctggcacaa ggggcgatgc aggcgctggt gaaagcgatg
    12481 cccgcctggt tgacccacgg ctttgaagtg gctggcggta ttctgcctgc cgttggtttt
    12541 ggcttgctgc tgcgcgtaat gttcaaagcg caatatatcc cttacctgat cgccggtttc
    12601 ctgtttgttt gctacatcca ggtcagcaac ctgttgccgg ttgccgtact gggcgcaggc
    12661 tttgcggtgt atgagttttt caatgcgaaa tcccggcagc aagcgcaacc gcagcccgtt
    12721 gccagtaaaa atgaagaaga ggactacagc aatgggatct gaaatcagta aaaaagatat
    12781 cacccgtctg ggctttcgtt cgtcgctgct gcaagcgagc tttaactacg aaaggatgca
    12841 ggcgggcggt tttacctggg cgatgttgcc gatcctgaaa aagatttata aggacgacaa
    12901 accgggctta agcgcggcga tgaaagataa cctcgaattt attaataccc acccgaatct
    12961 ggtcggattc ctgatggggt tattaatttc gatggaagaa aaaggagaaa accgcgacac
    13021 cattaaaggc ctcaaagtgg cactgtttgg cccaatcgcc gggattggcg atgcgatttt
    13081 ctggtttact ttgttgccga ttatggcggg aatttgctca tcatttgcca gccagggaaa
    13141 cctgctgggg ccgattctat ttttcgccgt ttacctgctt atctttttcc tgcgcgtcgg
    13201 ctggacccac gtcggttatt cagtcggcgt gaaggcgatc gataaagtgc gagagaactc
    13261 gcagatgatt gctcgctcgg caaccatcct cgggatcacg gtaatcggcg ggctgatcgc
    13321 ttcgtatgtg catattaacg tggtgacatc gtttgccatc gacagtaccc acagcgtcgc
    13381 gctgcaacag gatttcttcg ataaagtctt cccgaacatt ttaccgatgg cctacaccct
    13441 gctgatgtat tacttcctgc gggtgaaaaa agcgcatccg gtgctgttaa tcggcgtgac
    13501 ttttgtgctc tctattgttt gttccgcatt cggcattttg taaatggaac gaggcactgc
    13561 ttctggcggt gcctctttac ttaaggaatt tcatcctgtg caaacccttc agcaagttga
    13621 aaactatacg gcgttaagtg aacgagccag cgaatattta ttggctgtga tccgtagcaa
    13681 accggatgcc gtgatttgcc tggcgaccgg agccacgcca ttactgacgt atcattatct
    13741 ggtagaaaaa atccaccagc agcaggttga tatcagccag ctcaccttcg tgaagctcga
    13801 cgaatgggtg gatctgccat taacgatgcc tggcacctgc gaaactttcc tacaacagca
    13861 tatcgtgcag ccgctggggc tgcgtgaaga ccagctcatc agctttcgct ccgaagagat
    13921 aaatgagaca gagtgcgaac gggtaacgaa cctgattgcg cgcaaaggcg gtctggattt
    13981 atgcgttcta ggattgggga aaaacggtca tcttgggctg aacgaaccgg gagaaagcct
    14041 acaaccggcc tgccatatca gtcaacttga tgccagaaca cagcaacatg agatgttaaa
    14101 aaccacgggt cgccccgtga ctcgtgggat caccttaggc ctgaaggata ttctcaatgc
    14161 ccgcgaggtt ttgttattgg tgactggcga aggaaagcag gatgcgacag aacgttttct
    14221 cacggctaaa gtctccaccg ctatcccggc ttcgttttta tggctgcaca gtaactttat
    14281 ttgtttaatt aatacctaac cagatgaaaa tttgctcaaa atttttaaat taacttattc
    14341 aacagtcacg cattatatta aataacattt gactgggttg aacataacgc caatagcaaa
    14401 aggagttatg ttcaacaatt taattttaga tatacatata actt
//
LOCUS       DAPGUL010000112        14421 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.114, whole genome shotgun sequence.
ACCESSION   DAPGUL010000112 DAPGUL010000000
VERSION     DAPGUL010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14421
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.114"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            70..426
                     /locus_tag="RHX21_003658"
     CDS             70..426
                     /locus_tag="RHX21_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HDV1988784.1"
                     /translation="MQWYLAVLKNYVGFSGRARRKEYWMFTLINAIVGAIINVIQLIL
                     GLEFPFLSLIYLAATIIPVIALCVRRLHDTDRSGAWALLYLVPIIGWLVLFVFACLEG
                     NSGSNRYGNDPKFGSN"
     gene            complement(477..1373)
                     /gene="yhaJ"
                     /locus_tag="RHX21_003659"
     CDS             complement(477..1373)
                     /gene="yhaJ"
                     /locus_tag="RHX21_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YhaJ"
                     /protein_id="HDV1988785.1"
                     /translation="MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQK
                     LEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTIV
                     TEALVPTPAFFPLIDKLAAKANTQLAIITEVLAGAWERLEQGRADIVIAPDMHFRSSS
                     EINSRKLYTLMNVYVAAPDHPIHQEPEPLSEVTRVKYRGIAVADTARERPVLTVQLLD
                     KQPRLTVSTIEDKRQALLAGLGVATMPYPMVEKDIAEGRLRVVSPESTSEIDIIMAWR
                     RDSMGEAKSWCLREIPKLFSGK"
     gene            1478..2179
                     /locus_tag="RHX21_003660"
     CDS             1478..2179
                     /locus_tag="RHX21_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pirin family protein"
                     /protein_id="HDV1988786.1"
                     /translation="MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLN
                     QEVLAPGAAFQPRTYPKVDILNVILDGEAEYRDSEGNHVQASAGEALLLSTQPGVSYS
                     EHNLSKDKPLTRMQLWLDACPQRENPLIQKLALNMGKQQLIASPEGTMGSLQLRQQVW
                     LHHIVLDKGESANFQLHGPRAYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITL
                     VADSPLRALLIDLPV"
     gene            2202..2366
                     /locus_tag="RHX21_003661"
     CDS             2202..2366
                     /locus_tag="RHX21_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312016.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988787.1"
                     /translation="MSKKSAKKRQPVKPVVAKEPARTAKNFGYEEMLSELEAIVADAE
                     TRLAEDEATA"
     gene            complement(2578..3888)
                     /locus_tag="RHX21_003662"
     CDS             complement(2578..3888)
                     /locus_tag="RHX21_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HDV1988788.1"
                     /translation="MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAEL
                     EGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQ
                     AIADAKALLAAGKVSVKIQEPCNEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHNG
                     VVFTQQACVAEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEG
                     LSGKWGLHIGATLEKQCERGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQ
                     GITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAA
                     GMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDT
                     AVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR"
     gene            complement(3916..5247)
                     /locus_tag="RHX21_003663"
     CDS             complement(3916..5247)
                     /locus_tag="RHX21_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026203.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease"
                     /protein_id="HDV1988789.1"
                     /translation="MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMS
                     IGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESPECKDYPSV
                     ISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGL
                     VLICILVAISSRGEKLLFKISTGMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLV
                     KNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEVARHKALRAMNIAFGILFVTVFF
                     YAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVSVILNIFAVMTAFFG
                     VYLGFREATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAIVLNAPVLSFTS
                     ICSPIFGMVGCLIPAWLVYKVPALHKYKGMSLYLIIVTGLLLCVSPFLAFS"
     gene            complement(5522..6886)
                     /gene="tdcG"
                     /locus_tag="RHX21_003664"
     CDS             complement(5522..6886)
                     /gene="tdcG"
                     /locus_tag="RHX21_003664"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HDV1988790.1"
                     /translation="MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSH
                     IVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVIDEIPAFIELVTRSGRLPVASGA
                     HIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLS
                     HDVETSVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHD
                     GIERGMNTEGVLPGPLNVPRRAVALRRQLVSSDNISNDPMNVIDWINMYALAVSEENA
                     AGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAGAIGALYKMNASISG
                     AEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPC
                     IERNAINAVKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIK
                     VVCG"
     gene            complement(6958..7347)
                     /locus_tag="RHX21_003665"
     CDS             complement(6958..7347)
                     /locus_tag="RHX21_003665"
                     /EC_number="3.5.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312020.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enamine/imine deaminase"
                     /protein_id="HDV1988791.1"
                     /translation="MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPA
                     DVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQATY
                     PTRSCVQVARLPKDVKLEIEAIAVRSA"
     gene            complement(7361..9655)
                     /gene="tdcE"
                     /locus_tag="RHX21_003666"
     CDS             complement(7361..9655)
                     /gene="tdcE"
                     /locus_tag="RHX21_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-ketobutyrate formate-lyase/pyruvate
                     formate-lyase"
                     /protein_id="HDV1988792.1"
                     /translation="MKVDIDTSDKLYADAWLGFKGTDWKNEINVRDFIQHNYTPYEGD
                     ESFLAEATPATTELWEKVMEGIRIENATHAPVDFDTNIATTITAHDAGYINQPLEKIV
                     GLQTDAPLKRALHPFGGINMIKSSFHAYGREMDSEFEYLFTDLRKTHNQGVFDVYSPD
                     MLRCRKSGVLTGLPDGYGRGRIIGDYRRVALYGISYLVRERELQFADLQSRLEKGEDL
                     EATIRLREELAEHRHALLQIQEMAAKYGFDISRPAQNAQEAVQWLYFAYLAAVKSQNG
                     GAMSLGRTASFLDIYIERDFKAGVLNEQQAQELIDHFIMKIRMVRFLRTPEFDSLFSG
                     DPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEELPIAFKKYA
                     AQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYA
                     INGGVDEKLKIQVGPKTAPLMDDVLDYDKVMDSLDHFMDWLAVQYISALNIIHYMHDK
                     YSYEASLMALHDRDVYRTMACGIAGLSVATDSLSAIKYARVKPIRDENGLAVDFEIDG
                     EYPQYGNNDERVDSIACDLVERFMKKIKALPTYRNAVPTQSILTITSNVVYGQKTGNT
                     PDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKE
                     DPVRKTNLVGLLDGYFHHEADVEGGQHLNVNVMNREMLLDAIEHPEKYPNLTIRVSGY
                     AVRFNALTREQQQDVISRTFTQAL"
     gene            complement(9689..10897)
                     /gene="tdcD"
                     /locus_tag="RHX21_003667"
     CDS             complement(9689..10897)
                     /gene="tdcD"
                     /locus_tag="RHX21_003667"
                     /EC_number="2.7.2.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417585.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate kinase"
                     /protein_id="HDV1988793.1"
                     /translation="MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAF
                     LSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITD
                     EVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLP
                     WKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQS
                     VDTSMGMTPLEGLMMGTRSGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLS
                     SDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDGIIFTGGIGENSSLI
                     RRLVMEHLAVLGVEIDTEMNNRSNSCGERIVSSENARVICAVIPTNEEKMIALDAIHL
                     GKVNAPAEFA"
     gene            complement(10923..12254)
                     /gene="tdcC"
                     /locus_tag="RHX21_003668"
     CDS             complement(10923..12254)
                     /gene="tdcC"
                     /locus_tag="RHX21_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine transporter TdcC"
                     /protein_id="HDV1988794.1"
                     /translation="MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRA
                     GFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITF
                     LYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLM
                     VKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIM
                     VFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLF
                     TLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGH
                     YLGTLEGLNGLILKFGYKGDKTKVSLGKLNTISMIFIMGSTWVVAYANPNILDLIEAM
                     GAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF"
     gene            complement(12276..13265)
                     /gene="tdcB"
                     /locus_tag="RHX21_003669"
     CDS             complement(12276..13265)
                     /gene="tdcB"
                     /locus_tag="RHX21_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional threonine ammonia-lyase/L-serine
                     ammonia-lyase TdcB"
                     /protein_id="HDV1988795.1"
                     /translation="MHITYDLPVAIDDIIEAKQRLAGRIYKTGMPRSNYFSERCKGEI
                     FLKFENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVACSAGNHAQGVSLSCAMLGIDGK
                     VVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIA
                     GQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAA
                     SFHSGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQR
                     NKVVTEGAGALACAALLSGKLDQYIQNRKTVSIISGGNIDLSRVSQITGFVDA"
     gene            complement(13364..14302)
                     /gene="tdcA"
                     /locus_tag="RHX21_003670"
     CDS             complement(13364..14302)
                     /gene="tdcA"
                     /locus_tag="RHX21_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator TdcA"
                     /protein_id="HDV1988796.1"
                     /translation="MSTILLPKTQHLVVFQEVIRSGSIGSAAKELGLTQPAVSKIIND
                     IEDYFGVELVVRKNTGVTLTPAGQLLLSRSESITREMKNMVNEISGMSSEAVVEVSFG
                     FPSLIGFTFMSGMINKFKEVFPKAQVSMYEAQLSSFLPAIRDGRLDFAIGTLSAEMKL
                     QDLHVEPLFESEFVLVASKSRTCTGTTTLESLKNEQWVLPQTNMGYYSELLTTLQRNG
                     ISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTSPFGSNQFITIPVEETLPVAQYAAV
                     WSKNYRIKKAASVLVELAKEYSSYNGCRRRQLIEVG"
BASE COUNT         3734 a         3870 c         3369 g         3448 t
ORIGIN      
        1 aagatacgaa tagcatttac acaatacccg gaatagactt tcgtcacttt taattaaagg
       61 gatgttttta tgcagtggta tttagccgta ttaaaaaatt atgttggttt ctctggtcgc
      121 gcacgtcgta aagagtactg gatgtttact ctgattaacg ccatcgtcgg cgctattatc
      181 aatgtcattc aattgatttt aggtttagag tttccattcc tttctctcat ttacctggca
      241 gcaacaatca ttccggtcat tgctctgtgt gttcgtcgtc tgcacgatac tgaccgttca
      301 ggtgcgtggg cgcttctcta tctggtaccg atcattggct ggttagttct gtttgtattt
      361 gcctgtttag aaggcaattc tggcagcaat cgttacggaa acgatcctaa gtttggttca
      421 aattaatctt agaattgggg cgacatttcg ccccttttta ttaataataa caaatattat
      481 tttccgctaa aaagtttggg aatttcccgc agacaccagg atttcgcttc ccccatactg
      541 tcacgacgcc aggccataat aatatcgatc tcgctggtcg attccgggct gacgacacgc
      601 aaccgccctt ccgcaatatc tttttcgacc atcggatacg gcatcgtcgc cacgccaagc
      661 cccgccagta atgcctgacg tttatcttca atcgtgctca ccgttaagcg cggctgtttg
      721 tccagcagct gtacggtcaa caccgggcgc tcacgagcgg tatccgctac cgcaattcca
      781 cgatatttca cgcgcgtcac ttcagataac ggttccggct cctgatgaat cgggtgatca
      841 ggcgcggcaa cgtagacgtt cattaacgta tagagcttgc gcgagttgat ctccgacgag
      901 gaacgaaaat gcatatccgg cgcgataaca atatccgccc gcccctgctc cagtcgttcc
      961 cacgcccccg ccagcacttc ggtgatgatt gccagttggg tattggcttt tgccgccagt
     1021 ttgtcgatta acgggaaaaa ggcaggtgtc ggtaccagcg cttcggtcac aatggtgaga
     1081 tgcgtttccc aaccgcgcgc gagggcttcc gcatcggtag tcagtttatc tgcggcttcc
     1141 agcaaaacgc gccctcgctc cagcaacatc ctcccgacat tggtgaattt ggtgcgatgg
     1201 cccgagcggt caaacagcac cacatccagc tcttcttcca gtttttgcat ggtgtagcta
     1261 agtgcggaag gcacgcgtcc cagctcatcc gccgccgccg caaaactgcc ccggcgatcg
     1321 atcgcatcca taacccgtag tgcttccagc gttaatgccc tttctttggc catttcgttc
     1381 tcattcagga aatttgaaca taccgggcag aatatctggc taacaatgta gcgtccagcc
     1441 ccttaccata aaaggaagta aagagaggtc aagaattatg attactaccc gaactgccag
     1501 gcagtgtgga caagcagact acggatggtt gcaggcccgg tatacttttt cctttggaca
     1561 ctacttcgac ccgaaattgt taggctatgc ctccctgcgt gtgcttaacc aggaagtgct
     1621 ggccccaggt gccgcctttc agccgcgaac ctatcccaaa gtcgatattt taaatgtgat
     1681 tctggatgga gaagcagagt atcgcgacag cgaaggcaat catgttcagg ccagcgccgg
     1741 tgaggcgttg ctgctctcta cccagccggg tgtcagctac agcgaacaca atctcagcaa
     1801 agacaaaccg ttaacacgaa tgcagctttg gctggacgcc tgcccgcagc gagagaatcc
     1861 gctgattcaa aaactggcgc ttaatatggg caagcagcaa ttaatcgcct cgccagaggg
     1921 tacgatggga agcctgcaat tacgccagca agtgtggctg caccatatcg tgctcgacaa
     1981 aggcgaaagt gcgaatttcc agttgcatgg gccacgcgcg tatttgcaat cgattcacgg
     2041 gaaatttcat gcgcttacgc atcatgaaga gaaagcggcg ctgacctgcg gtgatggggc
     2101 gtttattcgt gacgaggcta acattacgct ggttgccgat tccccactgc gcgctttgct
     2161 gatagatttg cctgtctagt tgtttttaca gggagatgat gatgagtaaa aaatcggcca
     2221 aaaagcgcca gccagtgaag cccgtggtgg cgaaagaacc tgctcgcacc gccaaaaatt
     2281 ttggctatga agagatgttg agcgagctgg aagccatcgt cgcggatgct gaaacgcgtt
     2341 tagccgagga tgaagctacc gcgtaaagac aggttgccgg atgcggcgaa aacgccttat
     2401 ccggcctaca aaatccaaca acattaacga attaaacaac ccgtaggccg gataagatgc
     2461 gccagcatcg catccggcat caggtacaaa acacaacaac atcaacaagt tgagcacccc
     2521 gtaggccgga taaggtgcgc cagcatcgca tccggcacga tacccaaaac ctggcgttta
     2581 tctggccttg ctcgccataa tctcgataat ctgccgatcc gtttgctgca tcgaatggct
     2641 tgctaacgca cacaggttgg caatcgactg ctcaacatca tgcgccacga tcccttcatt
     2701 gccggtcacg gcggtatcat ccagcgccat taacaccgct ttccacgcag ccgaagcact
     2761 ggtcgaaacc ttcatcgcgc agctgttcga cgcaccatcg caaatcatgc cgctgacatc
     2821 gccgatcata ctgctgatcg ccatcgagat ggtttcataa cgcccatcca ccagccatgc
     2881 catcccggcg gcggccccca ttgctgcggt cgttgcggca cacagcgcag acaaacgcgg
     2941 taactggtta tggatgtaaa ttgcgctcaa atgagaaagc atcagcgcac gcgccagccg
     3001 ttcatcatcc gctccgaagt gttctgctac caccaccaca ggcattgttg cggtgatccc
     3061 ctggttaccc gagccggagt tactcatagc cggaagcgta gcgccgccca tacgcgcatc
     3121 ggatgccgcg ctggtacgaa tcacaatgga tgaagagaga tctttcgcca gcaaaccgcg
     3181 ctcgcactgt ttttccagcg tcgcgccaat atgcagcccc cacttaccgc tcaaaccttc
     3241 ctgcgataac gcacaattta gcttcgcgga atcgagaata aagcggatcg ccgcaaacgg
     3301 gacttcattg acgaacttca ggatctcagc cagcgtcgtt ctggaaagca ccgtcagcgg
     3361 agactcttgc tcgccctctg ccacacacgc ctgctgggta aacaccacac cattgtgcgt
     3421 ctcaatatgc acaatgttgg tatgcccgcc gacgatggtg acacacgccc acttctcacc
     3481 gttccagact ttggcgcgtg agaagaggat ttcattgcaa ggttcctgga tcttaacgga
     3541 gactttcccc gccgccagca gtgctttggc atcggcaatt gcctgcgcag ttgcgtcttt
     3601 cagcacttcc agcccggcgt tggcatttcc acctaacgcc cccagcgccg ccgcaatcgg
     3661 cagccccacc attcccgtgc cgggaacggt gacgcccaga ccgttcttca tcagatttgg
     3721 cgaaacccag gcttctacac gttcaaccgg accttccagt tctgccgcag caaccgccgc
     3781 cgccagcgcc agtgaaatcg gttcagtaca tcccagcgcc ggttttactt cctcctgaac
     3841 ggcgaggatg taacgctgcc ataacggatt taaagtcgaa tcaaacatat taaaaacctt
     3901 aaaatttcag gtaaatcaag aaaatgccag gaacggagaa acacaaagca acaaaccagt
     3961 gacgataatc aggtacagag acatcccttt gtatttgtgc aatgccggta ctttgtaaac
     4021 cagccacgcc gggatcaggc accctaccat gccgaaaatc gggctacaga tagaggtgaa
     4081 gctcaacacc ggtgcgttca gtacgatggc gctccaggcc agcaaaatgg cgaaaatcat
     4141 gatgccgcgc tgaacaagat tttcgttaat cttctcggca ggcatcttgc gacgcaggat
     4201 gttcattacg atcccttgcg ttgcttcgcg aaagcctaaa tagacgccaa agaatgcagt
     4261 catgacagca aagatattga gaatgacgct gaccactttc acccacgctg cgccgtcacc
     4321 gctaataaac tgtgcggcaa tcgccagcgc ggaaatattc tgctcatagg cttttaccgc
     4381 ttcgtcatgt cccatcgcca gcgtgaacga cacggcgtag aaaaagacgg tgacaaacaa
     4441 aatgccaaac gcgatattca ttgcccgcaa tgctttatgc cgcgccactt caattgattt
     4501 ttcccgcgag cgataagaga tcaccatcgg gcttaacgtc tggataaaca gaatcgacgt
     4561 cagggtaaac ggcagcgtaa taatggcgtt tttcaccagc agccccagcg gcggtagcga
     4621 accgacgtta tacagatgcc acattcccac catcgacacg cccagcgccg cgaccaccag
     4681 cagcttggtc agcaccatgc cggtcgaaat tttgaataac aatttctcgc cgcgtgaaga
     4741 gatcgccacc agaatgcaaa tcagtaccag accataaaag ggactgtctg acagcaaccc
     4801 ttccgtcacg ccgaaggtat gcagatagga agcactatcg ttggtgatgg cggtggaata
     4861 gacgaacatc caaatcacca gcattacgaa atagagcgca cctaacagga tgccccagtt
     4921 tttacctaaa taaccgctaa tgacactcgg gtaatcttta cattctggtg attctgccag
     4981 cgtattaata aacaaccgct gaaacagata cattgccggg taaccaatca ccgatgagag
     5041 caaaaatacc cacaatccca tcaaaccgac ctgcaccggg agaaaaacaa tccccgcgcc
     5101 aatcgccatc ccgatactca taatcaccca gccggtgtca gtactgtcga atttgatcgc
     5161 ttctcgccac tcgctctcac tcattccagc acgacccgcc ggggtcgaag cgtctgcaat
     5221 gacgccttta ttcgatgcaa tttccataat ttctcgctca atattttgta gggcttatta
     5281 tttttttccg agccgcatca aggcgatatg cggtctacgt ttttgcaggc gagttattag
     5341 aataaagaaa tgatacgcgc gaggtcagag aaaatcttca caatcaagac tttgaaataa
     5401 cggagatgga taagaatttt ctactaaatt aatcgcaaga gaatattcat tctctatttg
     5461 cggcagatca caaaaaaaag gtgcacattt gtgcacccaa ggatgaaagc tgacagcaat
     5521 gtcagccgca gaccacttta atggccagtc ctccgcgtga tgtttcgcgg tatttatcgt
     5581 tcatatcttt gccggtttca tacatcgtct cgatcacttt atcgagtgaa acacgcggtg
     5641 ccgaggtgcg gcgcatcgcc atccgcgcgg cgtttactgc tttcacggca ttaatggcat
     5701 tacgttcaat gcacgggatt tgtacctgtc cggcaaccgg atcgcaggtc agcccaaggt
     5761 tatgctccat cgcgatttcc gccgcattgc atacctgcgc cggactgccg cccagtagtt
     5821 cagttaaccc tgccgccgcc attgaacagg ccacgccaat ctccccctga cagccgacct
     5881 ccgcgccaga gatggaggcg ttcattttat acagcgcgcc aatagccccc gctgccagaa
     5941 aatagcgggc aattgaccgc tcgtttaccg gacgacggaa cttatcgtaa taagccagca
     6001 ctgccggaat aatgccgcac gcaccgttag tcggtgccgt taccacgcgc ccgccagctg
     6061 cgttttcttc actaaccgcc agcgcgtaca tgttgatcca gtcgatgaca ttcatcggat
     6121 cgttagagat gttatcgcta gaaaccagct gacgacgcag cgctacggca cgacgcggca
     6181 cattgagcgg accaggcaac acgccttcag tgttcatccc gcgttcaata ccgtcatgca
     6241 tcacttgcca gatacgggca aaccctgcgt caatttccgc tttactgcgc agcgctagct
     6301 cgttgtgcat catcaggcca gatatagaca ggccgttgta atcacacatt ttcagcagtt
     6361 cacctgctga gtggaaatcg taaggtacgg acgtttcgac atcgtgcgac aggccgaagt
     6421 gttcttcttc gacaataaac ccgccgccga cagagtaata ggttttactt aatagcgctt
     6481 cctgtccctt ccaggcagtg atccgcattc cgttctcatg gcgaggcaac atttcgggat
     6541 ggaagataat gttctttgct acaggaaaat caacaatatg cgcaccagat gccactggca
     6601 gccgcccgct gcgcgttact aactctataa atgcagggat ctcatcaatg acaacatcct
     6661 gcggactgtt tcctgccagt cccatgataa tggcgacatc cgtggcatgg cctttgcccg
     6721 tcagtgacaa cgacccatac agatcgacca caatatggct cgtcgcggtt aataagccgc
     6781 tactttccag ccgatcaata aaactttttc cggcattcat tggccccacg gtatgcgaac
     6841 tggagggacc aatcccaatt ttgaaaatat cgaatgcact aatcatatcc acaccctcgg
     6901 attgccgttc agtgaagtgg agcggaacga ccttgcgacc gtcccgctca cgaggcttta
     6961 cgcactacgt actgcgatag cttcaatttc cagcttcaca tctttcggca aacgcgcaac
     7021 ctgcacacag ctccgggtcg ggtaggtcgc ctgatgctca tcgaagaact gcttatagac
     7081 ttcattgatg gtggcaaaat cattcagatc ggtgatgaac acggtcatct tgatgatatc
     7141 gcccacgctc agcccggcag caaccacgat cgctttgacg ttttcgaggc ttaaacgcgc
     7201 ctgatcttgc acatcagccg ggatctcacc ggtctgcggg caaaccggaa tttgcccgga
     7261 ggtgaagacc atgctgccta aatcaacgcc ctgaacataa gggccgattg cgcctggggc
     7321 acgttgcgtt tcgataatct ttttcataca tcctccggcg tcagagcgcc tgggtaaaag
     7381 tacgtgaaat aacatcctgt tgctgttcac gggtcagtgc gttgaagcgc acggcgtagc
     7441 cagagacacg gattgtcagg ttaggatatt tttccgggtg ctcgatggca tccagcagca
     7501 tttcccgatt cattacgttg acgttgaggt gttgaccgcc ttcgacatcc gcttcgtggt
     7561 ggaaataccc atccagcagg ccgacaaggt tggttttacg tactggatct tctttgccca
     7621 gcgccgcagg aacgattgag aaggtgtacg agatcccatc tttggcgtag gtgaacggca
     7681 gtttcgccac cgacgtcaat gaggccacgg cacctttgcg gtcacgacca tgcatcgggt
     7741 tagcgcccgg cgcgaacggt gttccggcgc gacgaccgtc cggcgtatta ccggttttct
     7801 ggccgtacac cacgttagaa gtgatagtca gaatcgactg ggtagggacg gcgttgcgat
     7861 aggttggcag cgctttaatt ttcttcataa agcgttcaac caggtcgcag gcaatgctgt
     7921 ctacgcgctc gtcgttgttg ccgtactgcg gatattcacc gtcgatttca aagtccaccg
     7981 ccaggccgtt ttcgtcacgg attggtttca cgcgggcata tttgatggca gacagggagt
     8041 ccgtcgccac cgacaggccc gcgatgccgc atgccatagt gcgatagaca tcacgatcgt
     8101 gcagcgccat cagcgaagct tcgtagctgt acttgtcgtg catgtagtga atgatattca
     8161 gcgcgctgat gtactgcacc gccagccagt ccatgaagtg atcgaggctg tccatcactt
     8221 tgtcgtaatc cagcacgtcg tccatcagcg gtgctgtttt cggcccgacc tgaatcttca
     8281 gcttctcgtc caccccgccg ttaattgcgt agagcagcgt tttcgccagg ttagcgcgtg
     8341 caccaaagaa ctgcatttgc ttaccaatca ccattgggct gacgcagcag gcaatcgcgt
     8401 aatcgtcgct gttgaagtca gtacgcatca gatcgtcatt ttcatactgc aaggaagagg
     8461 tgacgatcga cacctgcgcg gcatattttt tgaaggcaat cggtaattct tccgaccaaa
     8521 gaatggtcag gttaggttcc ggtgccggcc ccatagtgtg cagggtgtgc aaatagcgga
     8581 aggagttttt ggtcaccagc gtacgaccgt ccagccccat cccgccgatc acttccgtcg
     8641 cccagattgg gtcgccggag aacagcgaat caaattccgg tgtacgcagg aagcgtacca
     8701 tacggatctt catgatgaag tgatcgatca gttcctgtgc ctgctgctca ttgagtacgc
     8761 cagctttaaa gtcgcgctca atgtagatat cgaggaacga tgccgtgcgg cccagcgaca
     8821 tcgcgccgcc attttgcgat ttcactgccg ccagataagc gaagtagagc cactgcaccg
     8881 cttcctgcgc attctgcgcc gggcgagaga tatcaaagcc atatttcgcc gccatttcct
     8941 gaatctgcaa cagcgcatga cgatgctctg ccagctcctc acgcagacgg atggtggctt
     9001 ccagatcctc gcctttttcc agacgagact ggagatcggc aaattgcagt tcgcgttcac
     9061 gtaccagata actgatgcca tacagcgcta cgcggcgata gtcaccgata atgcgcccac
     9121 ggccatagcc atctggtaaa ccggtcagca cgccagattt acggcagcgc agcatatccg
     9181 gtgagtaaac atcaaatacg ccctggttat gggttttacg cagatcggta aacagatatt
     9241 caaattcact gtccatttct cggccatagg cgtggaatga acttttaatc atattaatgc
     9301 caccgaacgg gtgtagcgca cgtttcaacg gcgcatccgt ttgcaggcca acaatttttt
     9361 ccagcggctg gttaatatat cccgcatcat gagcggtaat tgtggtggca atattggtat
     9421 cgaaatcaac cggcgcgtgg gttgcatttt cgatacggat gccttccatt actttttccc
     9481 acaattccgt ggtggcaggc gtcgcttcgg cgaggaaaga ttcatcgcct tcatacggtg
     9541 tatagttatg ttgaataaaa tcgcggacat taatttcgtt tttccagtcc gtacctttaa
     9601 agccaagcca tgcgtcggcg tacagcttat cgctggtatc aatatctacc ttcatgaaaa
     9661 ataatctctc tacaatactt caactaaatt atgcaaattc tgcgggcgcg ttaactttgc
     9721 ctaaatgaat ggcatccaaa gcaatcattt tttcttcgtt agtcggaata acggcacaaa
     9781 tgacacgcgc attttcactg gaaacaattc gctcaccaca ggagttagag cgattattca
     9841 tttctgtatc aatctctacg cctaatacag ccaaatgttc catgaccaga cgacgaatta
     9901 agcttgaatt ctctcctatt ccgccggtga atataattcc atccaggcga cgtaatgaag
     9961 ctgcgtgtcc ggcaatatga cgggcaattc ggtgaacaaa ggttttaatt gccagttgcg
    10021 cgcgttcgtg accttcatgc caggcttttt ccagaacacg taaatccgaa gaaagaccgg
    10081 aaatacctaa taatcccgac tctttattca ctacgcgttc caggtcaccc aggctctggt
    10141 tggtttggct ggcgacccag gacatcgcac caaagtcgac atcgccactg cgggtaccca
    10201 tcatcaagcc ttccagcggc gtcattccca ttgaagtatc aacactctga ccgttgcgaa
    10261 ccgcgcagat tgacgcgcca ttgccaagat gcgccacaac caggccggag tcatcttccg
    10321 ccagattcag cagcgaatgt gcgcgctggg aaacatagcg gtgcgacgtg ccgtggaaac
    10381 cataacggcg tacacctaac tcttcataat atttccacgg caggccgtat aaataagctt
    10441 ccggagccat cgtctggtgg aaactggtat caaataccgc cacctgagtt acgcccggaa
    10501 ataattgctg cgccgattca ataccactta aattggcgta attatgcagg ggtgccagtg
    10561 gagaaacgcg acggatatta tcaatgactt catcggtaat aatggcggac tcggtaaaaa
    10621 tactgccgcc gtgagcgatg cggtggccaa ttaaggccac actgtcattt aaattccgtt
    10681 tttccagttc aaatgcaatt gccttcaatg caccttcgta gctgtggtga gccagcggtg
    10741 ctggctctcc cccatttacg gataagaatg cattttccga gttaataccg tcggcaatac
    10801 ctgacattaa tacttcacag tcgctggcat cgagtacgga aaacttaatc gaagacgaac
    10861 cacagttaat aaccaaaaca accggaaatt cattcatctc ttttctcatc ctgagttacg
    10921 gattaaaaca gtttgtatac gatgttcagg atggtcagca gaccaatcac ggtaacaaac
    10981 acgttatcca gacgaccacg gtatttcgcc agagacggcg ctttacggat ggcatacatc
    11041 ggcaacaggc acagcaggga tgcgataatc ggtgcgccca tggcttcaat aaggtcgagg
    11101 atgttcgggt tggcgtaggc aacaacccag gtggagccca tgatgaagat catgctgata
    11161 gtgttcagtt tacccagcga cactttagtt ttgtcgcctt tataaccgaa cttcagaatc
    11221 agaccattca agccttccag cgtccccaga tagtgaccga agaaagattt gaagatagcc
    11281 acgagtgcga tgatggaagc cgcatattcc agtgtaatcg cgaacgttgt tttggtaccg
    11341 gtcatggacg caaagtggtt agccagataa gaaagcactg gaatattctg cgctttggct
    11401 tccgccatgt tggccggaga cagcgtaaac aggcagctaa aggcaaagaa catcaccact
    11461 gcaaccatca gcatgctggc acgagaaatg atttgggaac atttacgttc ggtgaagtcg
    11521 cgaccgaagt ctttctcata ctcttcacgt ttagaaacca cgaaggaaga gacgattggc
    11581 gagaagttaa aggagaaaac catgatggaa atccccagcc agacagtgat caggataccg
    11641 tcatgaccgg ttaacgacag cgaaccgagg tcaacctggt cgataactgc agagttccag
    11701 taagggatca gcgacagaga aatcagcacc aggctggcga taaacggcca taccaggtag
    11761 ctcatcactt taaccatcag atccttacca aaccagatga cgaaagccat cagcagcaac
    11821 aggaacagcg ccacaaagcc gcgattcagc ggtgcaaatc cgagctggtt ttcccagaac
    11881 gtcataaagg tattggtaat agtaacgcca taaatccaca gcagtgggca aatcgcgaag
    11941 aagtacagga acgtgataac cacgccgcca gttttaccaa aatgctcttc caccgtttcc
    12001 gtaatgttgc cggaagggtt agagccagaa agacacagac gcgccagcgc ccggtggcaa
    12061 taaaatgcga tggggtatgc caataccaac atcagaagaa tcgggatcag tccgccaaaa
    12121 cctgcgcgga tagggaagaa cagcaccccg gcgccgattg ccgtaccaaa caagcctaac
    12181 gtccatgtgg tatctgattt acgccaggac gattgttttg tctggctgga tacaatgcta
    12241 tctgaagtac tcatatccta tcctcaacga attaattaag cgtcaacgaa accggtgatt
    12301 tgagagacgc gagaaagatc gatattgccg ccggaaataa tactgacggt ttttctgttt
    12361 tgaatatatt ggtctaattt accgcttaat aatgcagcac atgccagagc gcctgcgcct
    12421 tcggtgacga ctttattgcg ctgaattaag gcaatcatac tgtttctgat ttcgtcttcg
    12481 ctgaccagca cgatgtcatc gactaattca cgaacgattt cgtaagttaa attacccggg
    12541 cgggagacat cacaaccatc cgccagggtg ccggtagttc ggtgcgtggt tatttctccg
    12601 gagtggaaag aagccgccat gccgtgaacg ttttctgact gtacgccaat aacacgaatg
    12661 gtcgggttaa tagatttaat tgccaccgca ataccagcaa ttaaaccacc accaccaatt
    12721 ggcacaatca cgttatcgac atcatagaga tcttccataa tttccagacc aatcgttccc
    12781 tggccagcaa tcactttcgg atcatcgtaa ggtgggataa aaatacgacc ttccatttcg
    12841 acaatttcgc tcactttagc gatagtgtcg ttgaaattat caccatgcag aacgacttct
    12901 gcggagtagt cgcacgttgc cgctactttg gattttggcg caccttttgg catcaccact
    12961 ttaccgtcga tacccagcat cgcgcaggag agcgaaaccc cttgcgcatg gttgcccgca
    13021 gaacaggcca ctacaccttt acgtttttcc gcatcagtca gtgaacttaa tttattaaat
    13081 gcgccacgaa ttttaaatga acccgtacgc tgcatatttt caaacttcag gaatatttca
    13141 cctttgcaac gttcactaaa atagtttgag cgaggcatgc ctgttttata aattcgccca
    13201 gccagtcgtt gtttcgcttc aataatgtca tcaatagcaa ccggcagatc gtatgtaata
    13261 tgcattataa aacctcttcg cctgaattaa atatgtaggt aaccgtaacc gacacctgca
    13321 aaacagacag gtggattatt tatgtttaaa taaaaacaaa taactaacca acttctatta
    13381 attgccttcg tctacaccca ttataagatg aatactcttt ggctaattcc accaaaaccg
    13441 atgctgcttt tttaatacga taatttttcg accataccgc ggcatattgt gccacaggta
    13501 atgtttcttc aaccggaata gtaataaatt gatttgaacc aaaaggtgac gtcatatcac
    13561 aaggaattac agttaagaaa tcagcattga gaacaagatt ataaattgtc acgactgagt
    13621 cggttttaac gatgttttca atactgatgc catttctttg taacgtagta agaagctcgc
    13681 tgtagtaccc catattggtt tgtggcaaca cccactgttc gttcttcaac gactccagcg
    13741 tggtggtgcc ggtgcatgtt cgggacttac tggctaccag cacaaactcg gactcgaaca
    13801 gcggctcaac atgtaaatcc tgaagcttca tttctgcact taacgtacca atcgcaaaat
    13861 ccagtcgacc gtcgcggatt gccggtaaga acgaagacag ttgcgcttca tacatagaaa
    13921 cctgcgcttt cgggaacacc tctttgaact tgttgatcat ccctgacata aaagtaaaac
    13981 caatcaatga aggaaaacca aatgagactt ccaccaccgc ctcagaagac ataccgctta
    14041 tctcattaac catatttttc atttcacggg taatggattc ggaacgggag agtaacaatt
    14101 gaccggcagg tgttaatgtt acaccggtat ttttccgcac cactaattcc acaccaaaat
    14161 aatcttcaat atcgttaatg attttactga cggctggttg agttaaccct aattcttttg
    14221 cagccgagcc gatagagcca cttctaatga cttcctgaaa gactaccagg tgctgcgttt
    14281 tcggaagaag aatagtgctc ataacgacct acgttaatta cctcattgac ggcatgaagt
    14341 gtatcaaaat gaaatgaaca ggatatgtgc gaccactcac aaattaactt tcaatacttt
    14401 ccatggtatc gttacgcaaa t
//
LOCUS       DAPGUL010000113        14149 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.115, whole genome shotgun sequence.
ACCESSION   DAPGUL010000113 DAPGUL010000000
VERSION     DAPGUL010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14149)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14149)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14149
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.115"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(121..873)
                     /gene="yecC"
                     /locus_tag="RHX21_003671"
     CDS             complement(121..873)
                     /gene="yecC"
                     /locus_tag="RHX21_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine ABC transporter ATP-binding protein
                     YecC"
                     /protein_id="HDV1988797.1"
                     /translation="MSAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTT
                     LLRSINLLEQPEAGTITVGDITIDTARSLSQQKSLIRQLRQHVGFVFQNFNLFPHRTV
                     LENIIEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALA
                     MRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMD
                     QGRIVEQGAAKALFADPQQPRTRQFLEKFLLQ"
     gene            complement(870..1538)
                     /gene="tcyL"
                     /locus_tag="RHX21_003672"
     CDS             complement(870..1538)
                     /gene="tcyL"
                     /locus_tag="RHX21_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine ABC transporter permease"
                     /protein_id="HDV1988798.1"
                     /translation="MQESIQLVIDSLPFLLKGAGYTLQLSIGGMFFGLLLGFILALMR
                     LSPIWPVRWLARFYISIFRGTPLIAQLFMIYYGLPQFGIELDPIPSAMIGLSLNTAAY
                     AAETLRAAISSIDKGQWEAAASIGMTPWQTMRRAILPQAARVALPPLSNSFISLVKDT
                     SLAATIQVPELFRQAQLITSRTLEVFTMYLAASLIYWIMATVLSTLQNHFENQLNRQE
                     REPK"
     gene            complement(1553..2539)
                     /gene="dcyD"
                     /locus_tag="RHX21_003673"
     CDS             complement(1553..2539)
                     /gene="dcyD"
                     /locus_tag="RHX21_003673"
                     /EC_number="4.4.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416429.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-cysteine desulfhydrase"
                     /protein_id="HDV1988799.1"
                     /translation="MPLHNLTRFPRLEFIGAPTPLEYLPRFSDYLGREIFIKRDDVTP
                     MAMGGNKLRKLEFLAADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENP
                     IGTTAENYLTNGNRLLLDLFNTQIEMCDALTDPNAQLEELATRVEAQGFRPYVIPVGG
                     SNALGALGYVESALEIAQQCEGAVNISSVVVASGSAGTHAGLAVGLEHLMPESELIGV
                     TVSRSVADQLPKVVNLQQAIAKELELTASAEILLWDDYFAPGYGVPNDEGMEAVKLLA
                     RLEGILLDPVYTGKAMAGLIDGISQKRFKDEGPILFIHTGGAPALFAYHPHV"
     gene            complement(2644..3444)
                     /gene="tcyJ"
                     /locus_tag="RHX21_003674"
     CDS             complement(2644..3444)
                     /gene="tcyJ"
                     /locus_tag="RHX21_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine ABC transporter substrate-binding
                     protein"
                     /protein_id="HDV1988800.1"
                     /translation="MKLAHLGRQALMGVMAVALVAGMSVKSFADEGLLNKVKERGTLL
                     VGLEGTYPPFSFQGDDGKLTGFEVEFAQQLAKHLGVEASLKPTKWDGMLASLDSKRID
                     VVINQVTISDERKKKYDFSTPYTISGIQALVKKGNEGTIKTAADLKGKKVGVGLGTNY
                     EEWLRQNVQGVDVRTYDDDPTKYQDLRVGRIDAILVDRLAALDLVKKTNDTLAVTGEA
                     FSRQESGVALRKGNEDLLKAVNDAIAEMQKDGTLQALSEKWFGADVTK"
     gene            complement(3532..4083)
                     /gene="fliZ"
                     /locus_tag="RHX21_003675"
     CDS             complement(3532..4083)
                     /gene="fliZ"
                     /locus_tag="RHX21_003675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310687.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulatory protein FliZ"
                     /protein_id="HDV1988801.1"
                     /translation="MMVQHLKRRPLSRYLKDFKHSQTHCAHCRKLLDRITLVRDGKIV
                     NKIEISRLDTLLDENGWQVEQKSWAALCRFCGDLHCKTQSDFFDIIGFKQFLFEQTEM
                     SPGTVREYVVRLRRLGNHLHEQNISLDQLQDGFLDEILAPWLPTTSTNNYRIALRKYQ
                     HYQRQTCTGLVQKSTSLPASDIY"
     gene            complement(4129..4848)
                     /gene="fliA"
                     /locus_tag="RHX21_003676"
     CDS             complement(4129..4848)
                     /gene="fliA"
                     /locus_tag="RHX21_003676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor FliA"
                     /protein_id="HDV1988802.1"
                     /translation="MNSLYTAEGVMDKHSLWQRYVPLVRHEALRLQVRLPASVELDDL
                     LQAGGIGLLNAVERYDALQGTAFTTYAVQRIRGAMLDELRSRDWVPRSVRRNAREVAQ
                     AIGQLEQELGRNATETEVAERLGIDIADYRQMLLDTNNSQLFSYDEWREEHGDSIELV
                     TDDHQRENPLQQLLDSNLRQRVMEAIETLPEREKLVLTLYYQEELNLKEIGAVLEVGE
                     SRVSQLHSQAIKRLRTKLGKL"
     gene            complement(5168..7180)
                     /locus_tag="RHX21_003677"
     CDS             complement(5168..7180)
                     /locus_tag="RHX21_003677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin FliC"
                     /protein_id="HDV1988803.1"
                     /translation="MAQVINTNSLSLITQNNINKNQSALSSSIERLSSGLRINSAKDD
                     AAGQAIANRFTSNIKGLTQAARNANDGISVAQTTEGALSEINNNLQRIRELTVQATTG
                     TNSDSDLDSIQDEIKSRLDEIDRVSGQTQFNGVNVLSKDGSMKIQVGANDGETITIDL
                     KKIDSDTLNLAGFNVNGKGSVANTAATSDDLKLAGFTKGTTDTNGVTAYTNTISNDKA
                     KASDLLANITDGSVITGGGANAFGVAAKNGYTYDAASKSYSFAADGADSAKTLSIINP
                     NTGDSSQATVTIGGKEQKVNISQDGKITAADDNATLYLDKQGNLTKTNAGNDTAATWD
                     GLISNSDSTGAVPVGVATTITITSGTASGMSVQSAGAGIQTSTNSQILAGGAFAAKVS
                     IEGGAATDILVASNGNITAADGDALYLDATIGGFTTTAGGNTAASLDNLIANSKDATL
                     TVTSGTGQNTVYSTTGSGAQFTSLAKVDTVNVTNAHVSAEGMANLTKSNFTIDMGGTG
                     TVTYTVSNGDVKAAANADVYVEDGALSANATKDVTYFEQKNGAITNSTGGTIYETADG
                     KLTTEATTASSSTADPLKALDEAISSIDKFRSSLGAVQNRLDSAVTNLNNTTTNLSEA
                     QSRIQDADYATEVSNMSKAQIIQQAGNSVLAKANQVPQQVLSLLQG"
     gene            7446..8852
                     /gene="fliD"
                     /locus_tag="RHX21_003678"
     CDS             7446..8852
                     /gene="fliD"
                     /locus_tag="RHX21_003678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HDV1988804.1"
                     /translation="MASISSLGVGSGLDLSSILDSLTAAQKATLTPISNQQSSFTAKL
                     SAYGTLKSALTTFQTANTALSKADLFSATSTTSSTTAFSATTAGNAIAGKYTISVSHL
                     AQAQTLTTRTTRDDTKTAIATSDSKLTIQQGGDKDPITIDISAANSSLSGIRDAINNA
                     KAGVSASIINVGNGEYRLSVTSNDTGLDNAMTLSVSGDDALQSFMGYDASASSNGMEV
                     SVAAQNAQLTVNNVAIENSSNTISDALENITLNLNDVTTGNQTLTITQDTSKAQTAIK
                     DWVNAYNSLIDTFSSLTKYTAVDAGADSQSSSNGALLGDSTLRTIQTQLKSMLSNTVS
                     SSNYKTLAQIGITTDPSDGKLELDADKLTAALKKDASGVGALIVGDGKKTGITTTIGS
                     NLTSWLSTTGIIKAATDGVSKTLNKLTKDYNAASDRIDAQVARYKEQFTQLDVLMTSL
                     NSTSSYLTQQFENNSNSK"
     gene            8877..9287
                     /gene="fliS"
                     /locus_tag="RHX21_003679"
     CDS             8877..9287
                     /gene="fliS"
                     /locus_tag="RHX21_003679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HDV1988805.1"
                     /translation="MYAAKGTQAYAQIGVESAVMSASQQQLVTMLFDGVLSALVRARL
                     FMQDNNQQGKGVSLSKAINIIENGLRVSLDEESKDELTQNLIALYSYMVRRLLQANLR
                     NDVSAVEEVEALMRNIADAWKESLLSPSLIQDPV"
     gene            9287..9652
                     /gene="fliT"
                     /locus_tag="RHX21_003680"
     CDS             9287..9652
                     /gene="fliT"
                     /locus_tag="RHX21_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulatory protein FliT"
                     /protein_id="HDV1988806.1"
                     /translation="MNHAPHLYFAWQQLVEKSQLMLRLATEEQWDELIASEMAYVNAV
                     QEIAHLTDEIDPSTTMQEQLRPMLRLILDNESKVKQLLQIRMNELAKLVGQSSVQKSV
                     LSAYGDQGGFVLAPQDNFS"
     gene            9730..11217
                     /gene="amyA"
                     /locus_tag="RHX21_003681"
     CDS             9730..11217
                     /gene="amyA"
                     /locus_tag="RHX21_003681"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HDV1988807.1"
                     /translation="MRNPTLLQCFHWYYPEGGKLWPELAERADGFNDIGINMVWLPPA
                     YKGASGGYSVGYDSYDLFDLGEFDQKGSIPTKYGDKAQLLAAIDALKRNDIAVLLDVV
                     VNHKMGADEKEAIRVQRVNADDRTQIDEEIIECEGWTRYTFPARAGQYSQFIWDFKCF
                     SGIDHIENPDEDGIFKIVNDYTGEGWNDQVDDELGNFDYLMGENIDFRNHAVTEEIKY
                     WARWVMEQTQCDGFRLDAVKHIPAWFYKEWIEHVQEVAPKPLFIVAEYWSHEVDKLQT
                     YIDQVEGKTMLFDAPLQMKFHEASRMGRDYDMTQIFTGTLVEADPFHAVTLVANHDTQ
                     PLQALEAPVEPWFKPLAYALILLRENGVPSVFYPDLYGAHYEDVGGDGQTYPIDMPII
                     EQLDELILARQRFAHGVQTLFFDHPNCIAFSRSGTDEYPGCVVVMSNGDDGEKTIHLG
                     ENYGNKTWRDFLGNRQESVVTDENGEATFFCNGGSVSVWVIEEVI"
     gene            complement(11251..11664)
                     /locus_tag="RHX21_003682"
     CDS             complement(11251..11664)
                     /locus_tag="RHX21_003682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310694.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDV1988808.1"
                     /translation="MKKLAIAGALMLLAGCAEVENYNNVVKTPAPDWLAGYWQTKGPQ
                     RALVSPEAIGSLIVTKEGDTLDCRQWQRVIAVPGKLTLMSDDLTNVTVKRELYEVERD
                     GNTIEYDGMTMERVDRPTAECAAALDKAPLPTPLP"
     gene            11851..13056
                     /gene="yedE"
                     /locus_tag="RHX21_003683"
     CDS             11851..13056
                     /gene="yedE"
                     /locus_tag="RHX21_003683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium metabolism membrane protein YedE/FdhT"
                     /protein_id="HDV1988809.1"
                     /translation="MSWQQFKHAWLIKFWAPIPAVIAAGILSTYYFGITGTFWAVTGE
                     FTRWGGQLLQLFGVHAEEWGYFKIIHLEGSPLTRIDGMMILGMFGGCFAAALWANNVK
                     LRMPRSRIRIMQAIIGGIIAGFGARLAMGCNLAAFFTGIPQFSLHAWFFAIATAIGSW
                     FGARFTLLPIFRIPVKMQKVSAASPLTQKPDQARRRFRLGMLVFFGMLGWALLTAMNQ
                     PKLGLAMLFGVGFGLLIERAQICFTSAFRDMWITGRTHMAKAIIIGMAVSAIGIFSYV
                     QLGVEPKIMWAGPNAVIGGLLFGFGIVLAGGCETGWMYRAVEGQVHYWWVGLGNVIGS
                     TILAYYWDDFAPALATDWDKINLLKTFGPMGGLLVTYLLLFTALMLIIGWEKRFFRRA
                     APQTAKEIA"
     gene            13053..13286
                     /gene="yedF"
                     /locus_tag="RHX21_003684"
     CDS             13053..13286
                     /gene="yedF"
                     /locus_tag="RHX21_003684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HDV1988810.1"
                     /translation="MKNIVPDYRLDMVGEPCPYPAVATLEAMPQLKKGEILEVVSDCP
                     QSINNIPLDARNHGYTVLDIQQDGPTIRYLIQK"
     gene            13393..14064
                     /locus_tag="RHX21_003685"
     CDS             13393..14064
                     /locus_tag="RHX21_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase"
                     /protein_id="HDV1988811.1"
                     /translation="MCGRFAQSQTREDYLALLAEDIERDIPYDPEPIGRYNVAPGTKV
                     LLLSERDEHLHLDPVFWGYAPGWWDKPPLINARVETAATSRMFKPLWQHGRAICFADG
                     WFEWKKEGDKKQPYFIYRADGQPVFMAAIGSTPFERGDEAEGFLIVTAAADQGLVDIH
                     DRRPLVLSPEAAREWMRQEISGKEASEIAVSGCVPAKQFSWHPVLRAVGNVKNQGAAL
                     IQPVC"
BASE COUNT         3445 a         3650 c         3507 g         3547 t
ORIGIN      
        1 tgcaagccat cacattctct tatgttatta atgagttatg ctgatttgtt aagcagtttt
       61 atcacgcttg aaatagcgtc ccgccccgac aggtgaatcg tcggggctga ttttttctta
      121 ttattgcagc agaaacttct cgaggaactg gcgggtgcga ggctgctggg gatcggcaaa
      181 taacgctttt gctgccccct gctcgactat ccgcccctgg tccataaaaa tcgcccggtc
      241 cgcaacatcc cgggcaaagc tcatttcgtg cgtcacaatc accatcgtgc gcttttcctg
      301 cgccagctga cggatggtgt tcaggacttc gcccaccagc tctggatcca gcgctgacgt
      361 tggctcgtca aacaaaatca cctcaggacg cattgccagc gcacgcgcaa tcgcaacacg
      421 ctgctgttga ccgccagaca aacgacgtgg atagctggtt tctttaccgg ccagcccaac
      481 tttcgccagt agctcgcgag cgcgcgccgt ggcctcttct ttcggttcgc ctttgacgat
      541 caccggccct tcaataatgt tctccagcac cgtacgatgc ggaaacaaat taaagttctg
      601 gaagacaaac ccgacgtgct gacgcaactg gcgaatcagc gatttttgct gacttaatga
      661 acgtgcagta tcaatagtga tatcgccaac ggtgatcgtt cccgcttcgg gttgttccag
      721 cagatttatg ctgcgtagca acgtggtttt gccggaacca ctcggaccga taattgccac
      781 cacttcgcca ggctttacct cgaggtcgat accgtgcagc accgtctgac cgtggaattt
      841 tttcaccagg ttcttaactt caatggcact cattttggtt ctctctcctg gcgattaagt
      901 tgattctcaa aatggttctg caacgtcgat aacacagtcg ccatgatcca gtagatgagc
      961 gaagccgcca gatacatggt gaacacctcc agcgtacgcg aggtaatcaa ctgcgcctga
     1021 cggaacagct ccggcacctg gattgtcgcg gccagcgacg tatcttttac caggctgata
     1081 aagctgttcg acagcggcgg caacgccaca cgcgccgcct gtggcaaaat cgcgcgacgc
     1141 atggtctgcc acggcgtcat accaatactg gctgccgctt cccactgacc tttatcaata
     1201 gaagaaatgg cggcgcgcag cgtttcggca gcataggcgg cagtgttcaa cgacagacca
     1261 atcattgctg acggaatggg atctaattcg ataccaaact gcggcaggcc gtaatagatc
     1321 ataaacagtt gtgcgatgag cggcgtacca cgaaaaatag agatataaaa acgcgccagc
     1381 cagcgcacgg gccagattgg cgacaggcgc atcagcgcga gaataaaccc gagcagtaag
     1441 ccaaaaaaca tgccgccgat actgagttgc agcgtatacc cagcaccttt cagcaggaac
     1501 ggcaaggaat caataaccag ttgtatactt tcttgcatga gcgtttccgg agctaaacgt
     1561 ggggatgata ggcgaacagc gcaggcgcac cgccggtatg aataaacaga atcggccctt
     1621 catctttgaa acgtttctga ctgataccgt caatcagacc cgccatcgct tttccggtat
     1681 acacaggatc aagcagaatg ccttccagcc gcgccagcaa tttcactgct tccatgcctt
     1741 cgtcgttcgg cacgccgtag ccaggtgcaa aatagtcatc ccagagtaaa atttccgctg
     1801 atgcggtcag ctccagttct ttcgcaatcg cctgttgtag gttaaccact ttcggcaatt
     1861 gatcggcaac ggaacgcgac acggtcacgc caatcagttc gctttcaggc atcaggtgtt
     1921 ccagcccaac agccagtccg gcgtgagttc cggcactgcc cgatgcgacc accaccgacg
     1981 aaatattaac cgccccttca cactgttgcg caatttccag cgcactctcc acataaccca
     2041 gcgcgcccag agcattagaa ccgccaaccg gaatgacata cgggcgaaag ccttgtgctt
     2101 cgactcgcgt cgccagctct tccagttggg cattgggatc ggtcagtgcg tcgcacattt
     2161 caatctgggt attgaacaga tccagcaaca aacgattgcc gttggttaaa tagttttctg
     2221 cggttgtgcc aataggattt tccagcagcg ccacgcagtg cagaccgagt ttcgccgcaa
     2281 ctgcggcagt ctggcgcaca tggttagact ggatcgcccc ggcagtaatc agcgtatcgg
     2341 caccttcacg cagagcatct gccgcgagaa attccagctt acgtaattta ttgccgccca
     2401 ttgccatggg tgtgacgtca tcccgtttga tgaaaatttc ccgtccaaga taatcagaaa
     2461 agcgcggcag atattcgagc ggcgttggcg cgccgataaa ctccagccgt ggaaaacggg
     2521 ttaaattatg cagtggcata acagcctccg atgtgtgttg ttgtgatttt cttattatgc
     2581 acgctgaaaa cgcgtaaata aaaaaggcgc tagtgaaagc gccctttttt gtcattatgc
     2641 tgattatttg gtcacatcag caccaaacca tttttcggaa agggcttgca gagtgccatc
     2701 tttttgcatt tccgcaattg catcattcac tgctttcagc aggtcttcat ttcctttacg
     2761 cagcgccacg ccagactcct gacgggagaa tgcttcaccg gttactgcca gcgtatcgtt
     2821 ggttttcttc accagatcca gcgccgccag acggtcaacg aggatcgcat cgatacggcc
     2881 tacgcgcaga tcctgatatt tggtcgggtc atcatcatag gtacgcacat cgacgccctg
     2941 aacattctga cgcagccact cttcatagtt ggtgcccagg ccgacaccca cttttttgcc
     3001 tttcagatca gcagctgttt taatggtgcc ttcgttacct tttttcacca gcgcctgaat
     3061 accggaaatg gtgtaagggg tagagaaatc gtattttttc ttgcgctcgt cagaaatggt
     3121 gacctgatta atcaccacat caatgcgttt agagtccagc gacgccagca taccgtccca
     3181 tttggtcggt tttagtgacg cctcaacgcc aagatgtttt gccagctgtt gggcaaattc
     3241 cacttcaaaa ccggttaatt tgccgtcatc cccctgaaaa ctgaacggcg gataagttcc
     3301 ttccagccct acgagcagcg taccgcgctc tttaacttta ttaagcagac cttcatctgc
     3361 aaaactttta acgctcatgc ccgcaaccag cgccacggcc atcacaccca tcaatgcctg
     3421 acgtcccaga tgtgctaatt tcatattcac cccgaatgtt gttatgtctg tttgcagtgt
     3481 agagccattg tttgtaaaca caaaaacaac tctgctacat cttattctta tttaatatat
     3541 atcagaagca ggcagactgg tggatttctg cacaagtccg gtacacgttt gacgctgata
     3601 gtgttgatac ttccgtaacg cgatgcggta attgttggtg ctggtagtgg gcagccacgg
     3661 ggcgaggatt tcatcaagga aaccgtcctg cagctgatcg agggaaatat tttgctcgtg
     3721 aagatgatta cccaaacggc gcagacgaac gacatattca cgcaccgtac ctgggctcat
     3781 ttcagtttgc tcaaaaagaa attgcttaaa gccgataata tcgaaaaaat cactctgcgt
     3841 tttgcaatgt aaatcaccgc aaaatcggca caatgccgcc catgattttt gttccacttg
     3901 ccagccattt tcatcaagca gcgtgtccag gcgggaaatc tcgattttat tcactatttt
     3961 gccgtcgcga acgagggtaa tgcgatcgag taatttacgg caatgcgcgc aatgggtctg
     4021 gctgtgttta aagtctttaa gatagcggct taatggccgt cttttcaggt gctgcaccat
     4081 cattaagaac tcctggtagt caaaattaaa gtgcggcatt tactgacgtt ataacttacc
     4141 cagtttagtg cgtaaccgtt taatggcctg gctgtgtaac tgactgaccc gcgattcccc
     4201 gacctccagc actgcaccaa tctctttgag attcagctct tcctggtaat agagggttaa
     4261 taccagtttt tcgcgctccg gcaacgtttc gatagcttcc atcacccgct ggcgcagatt
     4321 actgtccagc agttgttgta gcgggttttc tcgctgatga tcatcagtaa ccagttcaat
     4381 gctatcgccg tgctcttcgc gccactcatc gtaggagaag agctggctgt tattggtgtc
     4441 gagcaacatt tggcgataat cggcaatatc gatccctaaa cgttccgcta cctcagtttc
     4501 cgtggcgttg cggccaagtt cctgctccag ttgccctatt gcctgtgcca cttcacgcgc
     4561 gttgcgtcgc acgctgcgcg gcacccagtc acggctgcga agttcatcca gcatagcgcc
     4621 acggatacgc tgcactgcgt aagttgtaaa tgccgttcct tgtagggcgt catagcgttc
     4681 gacggcatta agtaacccaa tgccgcccgc ctgtagcaga tcgtcaagtt ccacgctcgc
     4741 gggcagtcga acctgcaggc gcaatgcttc gtgacgcacc agcgggacat aacgctgcca
     4801 cagcgagtgt ttatccatta caccttcagc ggtatagagt gaattcacga taaacagccc
     4861 tgcgttatat gagttatcgg catgattatc cgtttctgca gggtttttaa tcggacgatt
     4921 agtgggtgaa atgaggggtt atttgggggt taccggtaaa ttgcggacag aaaaaacccc
     4981 gccggtggcg gggaagcacg ttgctggcaa attaccattc atgttgccgg atgcggcgta
     5041 aacgccttat ccggcctaca aaaatgtgca aattcaataa attgcaattc accttgtagg
     5101 cctgataagc gcagcgcatc aggcaatttg gcgttgccgt cagtctcagt taatcaggtt
     5161 acgacgatta accctgcagc agagacagaa cctgctgcgg tacctggtta gcttttgcca
     5221 gcacggagtt accggcctgc tggatgatct gcgctttcga catgttggac acttcggtcg
     5281 catagtcggc gtcctgaata cgggactgcg cttcagacag gttggtagtg gtgttgttca
     5341 ggttggtgac cgcggaatcc agacggtttt gaaccgcacc gagggaggag cggaatttgt
     5401 cgatggagct gatggcttcg tccagagctt tcaggggatc ggcggtggaa ctggatgcag
     5461 tagtggcttc tgttgttaac ttaccatcag ctgtttcata gatggtacca ccggtgctgt
     5521 tggtaatagc cccatttttt tgttcaaagt aggttacatc ttttgtagca ttggctgaaa
     5581 gtgcaccatc ttcgacataa acatcagcat ttgcagcagc tttcacatcc ccattggaaa
     5641 ctgtgtaagt tactgtacct gtaccgccca tatcaatggt aaaattgctt tttgtcagat
     5701 ttgccatacc ttcggcactg acatgtgcgt tggtgacatt gacagtgtct acttttgcta
     5761 aactggtgaa ctgagcgcca cttcctgttg tgctataaac agtgttctgg ccggtacctg
     5821 aagttacggt taaggtagca tccttactgt tagcaattaa attatctaac gaagcagctg
     5881 tatttcctcc agccgttgta gtgaatccac caatagtcgc atcaagataa agtgcatcac
     5941 catcagccgc tgttatgttt ccattacttg ctaccaaaat gtctgtagca gcgcctccct
     6001 caatacttac cttagccgca aatgcaccac ctgcaagaat ctgagaattt gttgaggtct
     6061 gaattcctgc tcctgcggac tgaacagaca ttccggaagc tgtaccagaa gtaattgtaa
     6121 ttgtagttgc aaccccaact ggaaccgcac cggtagaatc gctgttggaa attaaaccat
     6181 cccaagtcgc tgcggtatcg ttacctgcat tcgtttttgt caagtttccc tgtttatcta
     6241 aatacagcgt cgcattatca tctgccgcag taatttttcc atcctgggaa atattaactt
     6301 tctgctcttt accaccaata gtcactgtcg cctgcgacga atcaccggtg tttggattaa
     6361 tgatgcttaa cgtcttcgct gaatcggcac catctgcagc aaaactataa gatttacttg
     6421 ctgcatcata ggtgtaacca ttctttgcag ccacgccaaa agcgtttgcc cctcccccag
     6481 tgatcactga tccatcggtg atattagcta acagatcgga agctttggct ttgtcattac
     6541 taattgtgtt tgtatacgcg gtcacgccat tggtatctgt ggtgccctta gtgaaaccag
     6601 ccagttttaa atcgtcgctt gtcgcagctg tattcgctac agaaccttta ccgttaacgt
     6661 taaaaccagc cagattcagc gtatcagagt caattttctt cagatcaata gtaatcgttt
     6721 cgccatcgtt cgcgccgacc tgaattttca tcgagccatc tttagacagc acgttcacgc
     6781 cgttgaactg ggtctgaccg gatacgcggt caatttcgtc cagacgagat ttgatttcgt
     6841 cctggatgga gtccaggtca gaatcggagt tagtccctgt agtggcctga accgtcagtt
     6901 cacgaatacg ctgtaagttg ttgttgattt cagacagcgc gccttcggtg gtctgtgcaa
     6961 cagaaatacc gtcgttggcg ttacgtgcag cctgagtcag gcccttgatg ttagaggtaa
     7021 aacggttagc aatcgcctga cccgctgcgt catccttcgc gctgttgata cgcaagccag
     7081 aagacagacg ctcgatagaa ctcgacagcg cagactggtt cttgttgata ttattttgag
     7141 tgatcagcga gaggctgttg gtattaatga cttgtgccat gattcgttat cctatattgc
     7201 aagtcgttga ttacgtattg ggtttccacc cgtcggctca atcgccgtca accctgttat
     7261 cgtctgtcgt aaaacaacct ttagaatttt tttcacaaac agccattttt tgttagtcgc
     7321 cgaaatactc ttttctctgc cccttattcc cgctattaaa aaaaacaatt aaacgtaaac
     7381 tttgcgcaat tcaggccgat aaccccggta ttcgttttac gtgtcgaaag ataaaaggaa
     7441 atcgcatggc aagtatttca tcgctgggag tcgggtcagg tctggattta agttcaatcc
     7501 tcgatagcct caccgccgcg caaaaagcga cgctaacccc tatttcaaat cagcaatcgt
     7561 cgtttaccgc taaacttagc gcctacggta cgctgaaaag cgcgttgacg actttccaga
     7621 ccgccaatac tgcattgtct aaagccgatc ttttttccgc caccagcact accagcagca
     7681 ccaccgcgtt cagtgccacc accgcgggta acgccatcgc cgggaaatac accatcagcg
     7741 tcagccatct ggcgcaggcg caaaccctga ccacgcgcac caccagagac gatacgaaaa
     7801 cggcgatcgc cactagcgac agcaaactca ccattcaaca aggcggcgac aaagatccga
     7861 ttaccattga tatcagcgcg gctaactcat cgttaagcgg gatccgtgat gccatcaaca
     7921 acgcaaaagc aggcgtaagc gcaagcatca ttaacgtggg taacggtgaa tatcgtctgt
     7981 cagtcacatc aaatgacacc ggccttgata atgcgatgac actctcggtc agcggtgatg
     8041 atgcgctaca aagttttatg ggctatgacg ccagtgccag cagcaacggt atggaggtct
     8101 cggtcgccgc ccagaatgcg cagctgacgg tcaacaacgt cgccatcgag aacagcagca
     8161 acactatcag cgacgcgctg gaaaacatca ccctgaacct gaacgatgtc accacgggca
     8221 accagacgct aaccatcact caggacacct ccaaagcgca aacagcgatt aaagactggg
     8281 tgaatgccta taactcgcta atagatacct tcagcagcct gaccaaatac accgccgtag
     8341 atgcgggagc tgatagccag agttctagca atggcgcact gctcggcgac tccacgttgc
     8401 ggacgattca gacgcagttg aagtcgatgc tgagtaatac cgtcagttct tccaactata
     8461 aaacgctggc gcagattggt atcacgaccg atcccagcga tggcaaactg gaactggatg
     8521 ccgacaaact caccgctgca ctgaaaaaag atgccagcgg cgtaggtgca ttgattgttg
     8581 gcgatggtaa aaaaaccggc atcacgacca ccatcggcag caacctgacc agttggcttt
     8641 cgacaacggg cattattaaa gccgctaccg atggcgttag taagaccctg aataaattaa
     8701 ctaaagacta caacgccgcc agcgatcgca ttgatgcgca ggtcgcgcgc tataaagaac
     8761 aatttaccca actggacgtt ttaatgacct cgttaaacag caccagcagc tacttaacgc
     8821 agcagttcga aaacaacagt aattccaagt aatcaatatt catcgggaga caggtcatgt
     8881 acgcggcaaa aggcacccag gcctatgcac aaattggcgt cgaaagcgcc gtaatgagcg
     8941 ccagccagca gcagctggtc accatgctat ttgatggagt gctaagcgca ctggttagag
     9001 cgcgcctgtt tatgcaggac aacaatcagc aaggcaaagg cgtctctttg tcaaaagcga
     9061 tcaacatcat tgagaacgga ctgcgggtga gtcttgatga agagagcaaa gacgaactaa
     9121 cccaaaactt gattgctctt tatagctata tggtcaggcg tttgctgcaa gccaatttac
     9181 gcaacgatgt ctccgcagtc gaagaagtgg aagcattaat gcgcaatatt gccgatgcct
     9241 ggaaagagtc gttactctcc ccttctttga ttcaggaccc agtctgatga accacgcacc
     9301 gcatttgtat ttcgcctggc aacaactcgt cgaaaaaagc cagctcatgt tacgcctggc
     9361 aacggaagaa caatgggacg aactcatcgc cagcgaaatg gcgtatgtga atgcggtgca
     9421 ggagattgca catctgactg atgagattga tccgtccacc acgatgcagg agcagctccg
     9481 cccgatgctg cgcctgattc tcgataacga aagcaaggta aagcagttat tacagattcg
     9541 gatgaatgaa ctggcgaaac tggtcggtca gtcatcggtg caaaaatcgg tgttaagtgc
     9601 ctatggcgat cagggcggct ttgtgctggc tccgcaagat aacttctcgt gaatcttaac
     9661 gagctaatgg ctcgcgaata atctgattac ggctacgctt ctaatgttcc ccttgaatgg
     9721 agtcgaagaa tgcgtaatcc cacgctgtta caatgttttc actggtatta cccggaaggc
     9781 ggtaagctct ggcctgaact ggccgagcgc gccgacggtt ttaatgatat tggtatcaat
     9841 atggtctggt tgccgcccgc ctataaaggc gcatcgggcg ggtattcggt cggctacgac
     9901 tcctatgatt tatttgattt aggcgagttt gatcagaaag gcagcatccc tactaaatat
     9961 ggcgataaag cacaactgct ggccgccatt gacgctctga aacgtaatga cattgcggtg
    10021 ctgttggatg tggtagtcaa ccacaaaatg ggcgcggatg aaaaagaagc tattcgcgtg
    10081 cagcgtgtaa atgctgatga ccgtacgcaa attgacgaag aaatcattga gtgcgaaggc
    10141 tggacgcgtt acaccttccc cgctcgtgcc gggcaatact cgcagtttat ctgggatttc
    10201 aaatgtttta gcggtatcga ccatatcgaa aatcctgatg aagatggcat atttaaaatt
    10261 gttaacgact acaccggcga aggctggaac gatcaggttg atgatgagtt aggtaatttc
    10321 gattatctga tgggcgagaa tatcgatttc cgcaatcatg ccgtgacgga agagattaaa
    10381 tactgggcgc gctgggtgat ggaacaaaca caatgcgacg gttttcgtct tgatgcggtc
    10441 aaacatatac cggcgtggtt ttataaagag tggatcgaac acgtacaaga agttgcgcca
    10501 aagccgctgt ttattgtggc ggagtactgg tcgcatgaag ttgataagct gcaaacgtat
    10561 attgatcagg tggaaggcaa aaccatgctg ttcgatgcgc cgctgcagat gaaattccat
    10621 gaagcatcgc gcatgggacg cgactacgac atgacgcaga ttttcactgg gacgctggtg
    10681 gaagccgatc cttttcacgc cgtaaccctc gttgccaacc acgacaccca accgttgcaa
    10741 gccctcgaag cgccggtcga accgtggttt aaaccgctgg cgtatgcctt aattttgttg
    10801 cgggaaaatg gcgttccttc ggtattctat ccggacctct acggtgcgca ttacgaagat
    10861 gtcggtggtg acgggcaaac ctatccgata gatatgccaa taatcgaaca gcttgatgag
    10921 ttaattctcg ctcgtcagcg tttcgcccac ggtgtacaga cgttattttt cgaccatccg
    10981 aactgcattg cctttagccg cagtggcact gacgaatatc ccggctgcgt ggtggtcatg
    11041 tcgaacgggg atgatggcga aaaaaccatt catctgggag agaattacgg caataaaacc
    11101 tggcgtgatt ttctggggaa ccggcaagag agcgtagtga ccgacgaaaa cggcgaagca
    11161 accttctttt gcaacggcgg cagcgtcagc gtgtgggtta tcgaagaggt gatttaaatt
    11221 catccccggc ggcaagccgg ggagatttca ttacggcagt ggcgtcggta acggcgcttt
    11281 atccagcgcg gcggcacact ctgccgtcgg gcgatccaca cgctccatcg tcataccatc
    11341 gtactcaatg gtgttaccgt cacgctcaac ctcgtatagc tcacgtttta cggtaacgtt
    11401 agtgagatca tcagacatca atgtcaactt acccggcacg gcaatcaccc gctgccactg
    11461 acggcaatca agagtatcgc cctctttagt gacaatcagg ctgcctatcg cttccgggct
    11521 gaccagcgca cgttgcggcc ctttggtctg ccagtagccc gccagccagt ccggcgcggg
    11581 ggttttcacg acattgttat agttttcgac ttcggcacag cccgccagca acatgagcgc
    11641 gcctgcaatt gcgagttttt tcatcattcg tcctgcatga gaagaaaaga ggattgtggc
    11701 attaaagccc tgatgtcgcc agcctttcca ggttcagaga gaaatttgat ctaactatta
    11761 tttttgtgaa ttattacccc gaaaataaat ttgcatgatg tatgattcgc gactcttgtt
    11821 tcaaaccttc tgagttcaga ggctacattc atgtcatggc agcaattcaa acacgcctgg
    11881 ttgattaaat tctgggcgcc catccccgcg gtcatcgcgg cgggtattct ctccacttac
    11941 tattttggca tcactggcac cttttgggct gtcacgggtg aatttacccg ttggggcggc
    12001 cagctcctgc agctgttcgg cgtccatgct gaagagtggg gttactttaa aattatccat
    12061 ctggaaggat cgccattaac ccgcatcgac gggatgatga tcctcggtat gtttggcggc
    12121 tgctttgccg cagcgctgtg ggccaacaat gtcaaactgc gcatgccacg cagccgtatc
    12181 cgcattatgc aggccatcat tggcggtatt atcgctggtt ttggcgcgcg tctggcaatg
    12241 ggctgtaacc tggcggcgtt ctttaccggt attcctcagt tctcgctgca tgcctggttc
    12301 tttgccatcg ccactgccat tggttcatgg tttggcgcac gctttaccct gctgcccatc
    12361 ttccgtattc ccgtgaaaat gcagaaagtt tctgccgcct caccgctgac gcaaaaaccg
    12421 gatcaggcgc ggcgtcgttt tcgtctcggg atgctggtct ttttcggtat gctgggctgg
    12481 gcgctgctca cggcgatgaa ccaacccaaa ctggggctgg caatgctgtt tggcgtcggc
    12541 tttggtttac tgattgaacg tgcgcaaatc tgctttactt cggcgttccg cgatatgtgg
    12601 atcaccggac gtacccacat ggcgaaagca atcattatcg gtatggcggt gagtgccatc
    12661 gggatcttca gttacgtaca gttaggcgtt gaacccaaaa tcatgtgggc gggaccaaac
    12721 gcggtaattg gtggtttact gtttggtttt ggcatcgtgc tggcaggcgg ctgcgaaacc
    12781 ggctggatgt accgcgcggt agaaggccag gtgcactact ggtgggtcgg tctgggcaac
    12841 gtgatcggct caacgattct ggcgtattac tgggatgatt tcgctccggc gctggccacc
    12901 gactgggaca aaatcaacct gctgaaaacc tttggcccga tgggtggcct gctggtgaca
    12961 tatttgctgt tgtttactgc gctgatgttg attatcggct gggaaaaacg cttcttccgc
    13021 cgtgcggcac cgcagactgc taaggagatc gcatgaaaaa tatcgttcct gattaccgcc
    13081 ttgatatggt gggtgaaccc tgcccttatc cggcagtcgc aactcttgag gcgatgccgc
    13141 agttaaaaaa aggggaaatc ctggaagtgg tgagcgactg tccacagtcg atcaataata
    13201 ttccactgga tgcgcgtaat cacggctata cggtgctgga tattcagcaa gacgggccga
    13261 ccattcgtta tttaattcag aagtaatccc tcattcccgc tgtggcccac agcgggaaca
    13321 tcgttgcctc tgacacatag attttacccg ccccctatcc tattcttttc agtatgatct
    13381 caggaggttt ctatgtgtgg acgctttgcc caatcccaaa cgcgtgaaga ttaccttgcg
    13441 cttctcgcgg aagatattga acgcgatatt ccctacgatc ccgaacccat tggcagatac
    13501 aacgtcgcgc cgggaaccaa agttcttctg ctcagtgaac gtgatgaaca ccttcatctg
    13561 gatccggttt tctggggata tgctcccgga tggtgggata aaccgccgct gattaacgcc
    13621 cgcgtagaaa ctgcggccac cagtcgtatg tttaaaccgc tctggcaaca tggtcgggca
    13681 atctgttttg ccgatggctg gtttgagtgg aaaaaagaag gcgacaaaaa acagccttat
    13741 tttatctatc gcgctgatgg acaacctgtt tttatggccg cgataggtag cacaccgttt
    13801 gagcgtggtg acgaagccga aggattttta attgtcactg cagcagcaga ccagggtctg
    13861 gtagatattc atgaccgccg cccgctggta ctgtcgccag aagctgcgcg ggaatggatg
    13921 cggcaagaga ttagcggtaa agaagcctca gaaatcgcgg tcagtggttg tgtgccagca
    13981 aagcagttct cctggcatcc ggtattgcgc gcggtgggta atgtcaaaaa ccagggcgca
    14041 gcgttaattc aacctgtctg ttaaccctgg agattattga tgaactaaaa tgtgtcacaa
    14101 gaaacctcta ttccagtgac acaattgcgc ctaattactt acatataat
//
LOCUS       DAPGUL010000114        14138 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.116, whole genome shotgun sequence.
ACCESSION   DAPGUL010000114 DAPGUL010000000
VERSION     DAPGUL010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14138
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.116"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            132..698
                     /locus_tag="RHX21_003686"
     CDS             132..698
                     /locus_tag="RHX21_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDV1988812.1"
                     /translation="MFKGQKTLAALAVSLLFTAPVYAADEGSGEIHFKGEVIEAPCEI
                     HQDDIDKEVELGQVTTSHINQSHHSDAVAVDLRLVNCDLENSSNGSGGKISKVAVTFD
                     SSAKTTGADPILNNTSTGEATGVGVRLMNKDQSNIVLGTATPDIDLAPTSSEQTLNFF
                     AWMEQIDQATPVTPGAVTANATYVLDYK"
     gene            749..3208
                     /locus_tag="RHX21_003687"
     CDS             749..3208
                     /locus_tag="RHX21_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706516.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDV1988813.1"
                     /translation="MDTVNIYRLSFVSCLVVAMPCALAVEFNLNVLDKSMRDRIDISL
                     LKEKGVIAPGEYFVSVAVNNNQISNGQKINWHKNDDKTIPCINDLLVDKFGLKPEVRQ
                     SLPLINQCVDFSSRPEMLFNFDQANQQLNITIPQAWLAWHSENWTPPSTWKEGVAGVL
                     MDYNLFASSYRPQDGSSSTNLNAYGTAGINTGAWRLRSDYQLNQTDSDDNHEQSGEIS
                     RTYLFRPLPQLGSKLTLGETDFSSNIFDGFSYTGAALASDDRMLPWELRGYAPQISGI
                     AQTNATVTISQSGRVIYQKKVPPGPFIIDDLNQSVQGTLDVKVTEEDGRVNNFQVSAA
                     STPFLTRQGQVRYKLAAGQPRPSMSHQTENETFFSNEVSWGMLSNTSLYGGLLLSGDD
                     YHSAAIGIGQNMLWLGALSFDVTWASSHFDTQQDERGLSYRFNYSKQVDATNSTISLA
                     AYRFSDRHFHSYANYLDHKYNDSDAQDEKQTISLSVGQPITPLNLNLYANLLHQTWWN
                     ADASTTANITAGFNVDIGDWRDISISTSFNTTHYEDKDRDNQIYLSISLPFGNGGRVG
                     YDMQNSSHSTTHRMSWNDTLDERNSWGMSAGLQSDRPDNGAQVSGNYQHLSSAGEWDI
                     SGTYAANDYSSVSSSWSGSFTATQYGAAFHRRSSTNEPRLMVSTDGVADIPVQGNLDY
                     TNHFGIAVVPLISSYQPSTVAVNMNDLPDGVTVAENVIKETWIEGAIGYKSLASRSGK
                     DVNVIIRNASGQFPPLGADIRQDDSGISVGMVGEEGHAWLSGVAENQKFTVVWGDSQH
                     CSLHLPEHMEDTANRLILPCH"
     gene            3223..3954
                     /locus_tag="RHX21_003688"
     CDS             3223..3954
                     /locus_tag="RHX21_003688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706517.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HDV1988814.1"
                     /translation="MTFMKGLPLLLLVASLCSHAALQPDRTRIVFNANDKATSLRVDN
                     RSDKLPYLAYSWLENEKGEKSDDLLVALPPIQRLEPKATTQVRIVKQASTTKLPGDRE
                     TLFFYNMREIPPAPEKNSDHAVLQVAIQSRIKVFWRPAALRKKAGEKVELQLQVSQQG
                     NQLTLKNPTAYYLTIAYLGRNEKGVLPGFKTVMVAPFSTVNTNTGNYSGSQFYLGYMD
                     DYGALRMTTLNCSGQCHLQAVEAKK"
     gene            3951..5012
                     /locus_tag="RHX21_003689"
     CDS             3951..5012
                     /locus_tag="RHX21_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415244.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV1988815.1"
                     /translation="MSAGKGVLLVICLLFLPLKSALALNCYFGSSGGSVEKSEAIQPF
                     AVPGNAKLGDKIWESDDIKIPVYCDNNTNGNFESEHVYAWVNPYPGVQDRYYQLGVTY
                     NGVDYDANQGKSRIDTNQCIDSKNIDIYTPEQIIAMGWQNKICSGDPANIHMSRTFLA
                     RMRLYVKIREMPPHDYQSTLSDYIVVQFDGAGSVNEDPTAQNLKYHITGLENIRVLDC
                     SVNFSISPETQVIDFGKFNLLDIRRHTMSKTFSIKTTKSQNDQCTDGFKVSSSFYTEE
                     TLVEEDKALLIGNGLKLRLLDENASPYTFNKYAEYADFTSDMLIYEKTYTAELSSIAG
                     TPIEAGPFDTVVLFKINYN"
     gene            5164..6210
                     /locus_tag="RHX21_003690"
     CDS             5164..6210
                     /locus_tag="RHX21_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415243.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDV1988816.1"
                     /translation="MPVLQWGMLCVLSLLLSIGFLAVHLPAALLLGPMIAGIIFSMRG
                     ITLQLPRSAFLAAQAILGCMIAQNLTGSILTTLAANWPIVLAILLVTLLSSAIVGWLL
                     VRYSSLPGNTGAWGSSPGGAAAMVAMAQDYGADIRLVAFMQYLRVLFVAGAAVLVTRM
                     MLGDNAEAVNQQIVWFPPVSINLLLTILLAVVAGTAGCMLRLPSGTMLIPMLAGAVLQ
                     SGQLITIELPEWLLAMAYMAIGWRIGLGFDKQILLRALRPLPQILLSIFALLAICAGM
                     AWGLTRFMHIDFMTAYLATSPGGLDTVAVIAAGSNADMALIMAMQTLRLFSILLTGPA
                     IARFISTYAPKRSA"
     gene            complement(6207..6998)
                     /gene="nei"
                     /locus_tag="RHX21_003691"
     CDS             complement(6207..6998)
                     /gene="nei"
                     /locus_tag="RHX21_003691"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease VIII"
                     /protein_id="HDV1988817.1"
                     /translation="MPEGPEIRRAADNLEAAIKGKPLTDVWFAFPQLKTYQSQLIGQH
                     VTHVETRGKALLTHFSNDLTLYSHNQLYGVWRVVDTGEEPQTTRVLRVKLQTADKTIL
                     LYSASDIEMLRPEQLTTHPFLQRVGPDVLDPNLTPEVVKERLLSPRFRNRQFAGLLLD
                     QAFLAGLGNYLRVEILWQVGLTGNHKAKDLNAAQLDALAHALLEIPRFSYATRGQVDE
                     NKHHGALFRFKVFHRDGELCERCGGIIEKTTLSSRPFYWCPGCQH"
     gene            complement(7034..7768)
                     /gene="pxpA"
                     /locus_tag="RHX21_003692"
     CDS             complement(7034..7768)
                     /gene="pxpA"
                     /locus_tag="RHX21_003692"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpA"
                     /protein_id="HDV1988818.1"
                     /translation="MKIDLNADLGEGCASDAELLTLVSSANIACGFHAGDAQTMQACV
                     REAIKNGVAIGAHPSFPDRENFGRSAMQLPPETVYAQTLYQIGALATIARAQGGVMRH
                     VKPHGMLYNQAAKEAQLADAIARAVYACDPALILVGLAGSELIRAGKQYGLTTREEVF
                     ADRGYQADGSLVPRSQPGALIENEEQALAQTLEMVQHGRVKSITGEWATVTAQTVCLH
                     GDGEHALAFARRLRSTFAEKEIVVAA"
     gene            complement(7758..8690)
                     /gene="pxpC"
                     /locus_tag="RHX21_003693"
     CDS             complement(7758..8690)
                     /gene="pxpC"
                     /locus_tag="RHX21_003693"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpC"
                     /protein_id="HDV1988819.1"
                     /translation="MLKIIRAGMYTTVQDGGRHGFRQSGISHCGALDMPALRIANLLV
                     GNDANAPALEITLGQLTVEFETDGWFALTGAGCEARLDDNAVWTGWRLPMKAGQRLTL
                     KRPQHGMRSYLAVAGGIDVPPVMGSCSTDLKVGIGGLEGRLLKDGDRLPIGKAKRDFM
                     EAQGVKQLLWGNRIRALPGPEYHEFDRASQDAFWRSPWQLSSQSNRMGYRLQGQILKR
                     TTDRELLSHGLLPGVVQVPHNGQPIVLMNDAQTTGGYPRIACIIEADMYHLAQIPLGQ
                     PIHFVQCSLEEALKARQDQQRYFEQLAWRLHNEN"
     gene            complement(8684..9340)
                     /gene="pxpB"
                     /locus_tag="RHX21_003694"
     CDS             complement(8684..9340)
                     /gene="pxpB"
                     /locus_tag="RHX21_003694"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HDV1988820.1"
                     /translation="MQRARCYLIGETAVVLELEPPVTLASQKRIWRLAQRLVDMPNVV
                     EAIPGMNNITVILRNPESLALDAIERLQRWWEESEALEPESRFIEIPVVYGGAGGPDL
                     AVVAAHCGLSEKQVVELHSSVEYVVWFLGFQPGFPYLGSLPEQLHTPRRAEPRLLVPA
                     GSVGIGGPQTGVYPLATPGGWQLIGHTSLSLFDPARDEPILLRPGDSVRFVPQKEGVC
                     "
     gene            complement(9363..10106)
                     /gene="ybgI"
                     /locus_tag="RHX21_003695"
     CDS             complement(9363..10106)
                     /gene="ybgI"
                     /locus_tag="RHX21_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radiation resistance protein YbgI"
                     /protein_id="HDV1988821.1"
                     /translation="MKNTELEQLINEKLNSAAISDYAPNGLQVEGKETVQKIVTGVTA
                     SQALLDEAVRLGADAVIVHHGYFWKGESPVIRGMKRNRLKTLLANDINLYGWHLPLDA
                     HPELGNNAQLAALLGITVMGEIEPLVPWGELTMPVPGLELASWIEARLGRKPLWCGDT
                     GPEVVQRVAWCTGGGQSFIDSAARFGVDAFITGEVSEQTIHSAREQGLHFYAAGHHAT
                     ERGGIRALSEWLNENTDLDVTFIDIPNPA"
     gene            10377..11858
                     /gene="dtpD"
                     /locus_tag="RHX21_003696"
     CDS             10377..11858
                     /gene="dtpD"
                     /locus_tag="RHX21_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide permease DtpD"
                     /protein_id="HDV1988822.1"
                     /translation="MNKHASQPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYND
                     THAYELFSAYCSLVYVTPILGGFLADKVLGNRMAVMLGALLMAIGHVVLGASEIHPSF
                     LYLSLAIIVCGYGLFKSNVSCLLGELYEPTDPRRDGGFSLMYAAGNVGSIIAPIACGY
                     AQEEYSWAMGFGLAAVGMIAGLVIFLCGNRHFTHTRGVNKKVLRATNFLLPNWGWLLV
                     LLVATPALITVLFWKEWSVYALIVATIIGLGVLAKIYRKAENQKQRKELGLIVTLTFF
                     SMLFWAFAQQGGSSISLYIDRFVNRDMFGYTVPTAMFQSINAFAVMLCGVFLAWVVKE
                     SVAGNRTVRIWGKFALGLGLMSAGFCILTLSARWSAMYGHSSLPLMVLGLAVMGFAEL
                     FIDPVAMSQITRIEIPGVTGVLTGIYMLLSGAIANYLAGVIADQTSQASFDASGAINY
                     SINAYIEVFDQITWGALACVGLVLMIWLYQALKFRNRALALES"
     gene            complement(11900..13318)
                     /gene="phrB"
                     /locus_tag="RHX21_003697"
     CDS             complement(11900..13318)
                     /gene="phrB"
                     /locus_tag="RHX21_003697"
                     /EC_number="4.1.99.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HDV1988823.1"
                     /translation="MTTHLVWFRQDLRLHDNLALAAACRNSSARVLALYIATPRQWET
                     HNMSPRQAELINAQLNGLQIALAEKGIPLLFREVDDFVASVEIVKQVCAENSVTHLFY
                     NYQYEVNERARDVEVERALRNVVCEGFDDSVILPPGAVMTGNHEMYKVFTPFKNAWLK
                     RLREGMPECVAAPKVRSSGSIEPSPSITLNYPRQSFDTAHFPVEEKAAIAQLRQFCQN
                     GAGDYEQQRDFPAVEGTSRLSASLATGGLSPRQCLHRLLAEQPQALDGGAGSVWLSEL
                     IWREFYRHLMTYYPSLCKHRPFIAWTDRVQWQSNPAHLQAWQKGKTGYPIVDAAMRQL
                     NSTGWMHNRLRMITASFLVKDLLIDWREGERYFMSQLIDGDLAANNGGWQWAASTGTD
                     AAPYFRIFNPITQGEKFDREGEFIRRWLPELRDVPGKAVHEPWKWAQKAGVKLDYPQP
                     IVDHKEARLRTLAAYEEARKGA"
     gene            complement(13315..13824)
                     /locus_tag="RHX21_003698"
     CDS             complement(13315..13824)
                     /locus_tag="RHX21_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgA family protein"
                     /protein_id="HDV1988824.1"
                     /translation="MNQQRFDDSTLIRIFALHELYRLKEHGLTRGALLDYHSRYKLVF
                     LAHSQPEYRKLGPFVADIHRWQNLDDYYNQYRQRVIVLLSHPANTRDHTNVLMHVQGY
                     FRPHIDSTERQQLAALIDSYRRGEQPLLAPLMRIKHYMALYPDAWLSGQRYFELWPRV
                     INLRHSGVL"
     gene            complement(13975..14138)
                     /locus_tag="RHX21_003699"
                     /pseudo
     CDS             complement(13975..14138)
                     /locus_tag="RHX21_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3426 a         3784 c         3430 g         3498 t
ORIGIN      
        1 taccatcaat taattacttt tacatttaat aaaattaata atatttttaa gaaaaactaa
       61 aaacattcga caatcaaata agatattctt gcaccgatat acttttttct tttctgttaa
      121 aggactccgt tatgtttaaa ggacaaaaaa cattggccgc actggccgta tctctgctgt
      181 tcacagcacc tgtttatgcg gctgatgaag gatccggtga aattcacttt aaaggtgaag
      241 ttattgaagc accgtgtgaa atacatcagg atgatattga taaagaggtt gaactcggtc
      301 aggtgaccac cagccacatt aatcagtcac atcacagcga tgccgttgct gtcgacctgc
      361 gcttagtcaa ctgtgatctg gaaaactcca gcaacggttc cggtggcaag atttctaaag
      421 ttgcagtcac ctttgatagc tcagcgaaaa ccaccggcgc agatccgatt ctcaacaaca
      481 ccagcacggg tgaagccacc ggcgtcggcg tacgtttaat gaataaagat caaagcaata
      541 tcgttttagg caccgctact ccagatatcg acctggctcc gacctccagc gaacaaacgc
      601 tgaatttctt tgcctggatg gaacaaattg atcaggctac acctgtaacg ccaggcgcag
      661 ttacggcgaa tgcaacctac gtgctggatt ataaataagt attactttgg cggcgctatc
      721 gccgcctttc ataaaatatt tatcaggtat ggacaccgtg aatatttatc gactctcttt
      781 tgtatcctgc ctggtcgtgg cgatgccttg cgcattggcg gtcgaattca accttaatgt
      841 tctcgataaa tcaatgcgcg accgcattga tatttcatta ttaaaggaaa aaggagtcat
      901 tgctcccggt gagtattttg ttagcgttgc ggtaaataat aaccaaatca gtaacgggca
      961 aaagattaac tggcacaaaa atgacgataa aaccattccg tgcatcaatg atttactggt
     1021 cgataaattt ggcttaaaac ctgaagtccg tcagtcgtta ccattgataa atcagtgcgt
     1081 cgattttagc tcccgacctg aaatgctctt caatttcgat caagccaatc agcaactaaa
     1141 tatcaccatt ccgcaagcct ggctggcgtg gcactcagaa aactggaccc caccctccac
     1201 atggaaagaa ggtgtcgccg gtgtcctgat ggattacaac ttgtttgcca gcagctaccg
     1261 cccacaggat ggcagcagca gcactaatct taacgcctat ggaacagccg gaatcaacac
     1321 gggggcatgg cgcttacgca gtgattatca gttgaatcag actgatagcg atgataacca
     1381 tgaacagtca ggcgaaatat cacgtaccta tctttttcgc ccgttaccgc aattaggttc
     1441 aaaattaacc ctcggcgaaa cggattttag ttccaatatt ttcgacggtt tttcttatac
     1501 cggcgcggca ctggcaagtg acgatcgaat gttgccatgg gaactacgcg gctacgcccc
     1561 acaaattagc ggtattgcac agaccaatgc cacggtgacg atcagtcaat caggccgcgt
     1621 catttaccag aaaaaagtcc caccaggccc atttatcatt gacgacctta atcagtctgt
     1681 tcagggcaca ctggatgtca aagtgacgga agaagatggt cgggtgaaca atttccaggt
     1741 ttcggcagca tcgacgccct tcctgactcg tcagggacag gttcgctata aactggccgc
     1801 gggtcagcca cggccctcca tgtcacatca aactgaaaat gaaacctttt ttagcaatga
     1861 agtttcctgg gggatgctgt caaacacctc gctgtacggc ggcctgctgc tttctggtga
     1921 tgactaccat tctgccgcaa taggtatcgg gcaaaatatg ctgtggcttg gcgcgctgtc
     1981 gtttgatgtc acgtgggcca gtagtcactt tgatactcag caggacgagc ggggcttaag
     2041 ctaccgtttt aattacagca aacaagtgga tgccaccaac agcacgattt ccctcgccgc
     2101 ttatcgtttc tccgatcgtc attttcacag ctacgccaac tatctggatc acaaatacaa
     2161 cgacagcgat gcgcaggacg aaaaacagac gatcagctta tctgtgggcc aaccgattac
     2221 cccactaaac ctcaatcttt acgccaacct gctacatcaa acctggtgga atgcagacgc
     2281 ctccacgacc gccaacatca cggcaggttt taatgttgat attggtgact ggagagatat
     2341 ctctatttcg acgtcattca atacaaccca ttacgaagat aaagatcgcg acaaccagat
     2401 ttacctgtcg atttcgctcc ccttcggtaa cggtggtcgg gttggctatg acatgcaaaa
     2461 cagtagccac agcaccacac accgcatgtc gtggaacgat acgctggatg aacgtaatag
     2521 ctggggcatg tctgccggac tgcaatccga ccgtccggac aatggagccc aggtgagcgg
     2581 taactatcag cacctgagtt cagcgggtga gtgggatatt tctggtacct atgccgccaa
     2641 tgattacagt tccgtcagca gcagctggag cggttctttc accgcaaccc aatatggtgc
     2701 agcgtttcat cgccgcagct ccaccaatga accacgcctg atggtcagca ccgatggcgt
     2761 ggcagatatt ccggttcagg gcaatctcga ctacaccaac cattttggca ttgcggtggt
     2821 gccgttgatt tccagttacc agccttccac cgtggcggtg aacatgaatg acttacccga
     2881 cggcgtaaca gttgcagaaa acgttatcaa agaaacgtgg attgaaggcg cgataggtta
     2941 caaatcactg gcttcccgtt ccggtaaaga cgttaacgtc atcattcgca acgccagcgg
     3001 tcagtttcct cccctcggag cggatatccg ccaggatgac agcggcatta gcgtggggat
     3061 ggttggcgag gaaggacatg cctggttaag cggagtcgct gaaaatcaaa agtttaccgt
     3121 ggtctggggt gatagccagc attgctcgct ccatcttcct gaacatatgg aagacaccgc
     3181 aaatcgcctg attttacctt gtcattaatt aaggaaatga aaatgacatt tatgaaagga
     3241 ctaccccttt tgttgttggt tgccagtctg tgcagccacg ctgcactaca acccgatcgc
     3301 actcgtattg tgtttaacgc taatgataaa gctaccagtc tgcgggtgga taatcgtagc
     3361 gataaactcc cctacctcgc ttattcctgg ctcgaaaatg aaaaagggga gaaaagcgat
     3421 gatcttctgg tcgccctgcc gccgatacaa cgtctggaac cgaaagcaac aacgcaggta
     3481 cggatagtaa agcaagcctc gaccacaaaa ttaccgggcg atcgcgaaac gctatttttc
     3541 tacaatatgc gtgaaattcc tcccgccccg gaaaaaaaca gcgaccatgc cgttctgcaa
     3601 gtcgccattc agagtcgtat caaggtgttc tggcgaccgg ctgcattacg caagaaagca
     3661 ggagaaaagg tcgaactgca gttacaggtc agccagcagg gcaaccaact gacactgaaa
     3721 aatcctaccg cgtattatct gaccattgcc tacctgggac gaaatgaaaa aggcgttctc
     3781 cccggcttca aaaccgtgat ggttgcgcct tttagtacgg tcaacacaaa caccggaaat
     3841 tatagcggca gccagtttta tctcggttat atggatgatt acggcgcgtt acgcatgacg
     3901 acgctcaact gcagcggaca atgccattta caagccgtgg aggcgaagaa atgagtgctg
     3961 gcaagggagt gttgctcgtc atctgtctgt tatttctgcc gttgaagtct gcgcttgccc
     4021 tgaactgcta ctttggttca tccggtggct cggtagaaaa atcagaagcg attcaacctt
     4081 ttgctgtacc aggcaatgcc aaactcggcg ataagatttg ggaatctgac gatattaaaa
     4141 ttcccgtcta ttgtgacaac aataccaacg gcaattttga aagtgagcat gtttatgcct
     4201 gggtaaaccc ctacccgggg gtgcaggatc gctattatca actcggcgta acttacaatg
     4261 gcgttgatta tgacgccaac cagggaaaaa gccgcatcga cactaaccag tgtattgaca
     4321 gtaagaacat tgacatttat acccctgagc agattatcgc gatgggatgg cagaacaaaa
     4381 tttgctcggg tgatcccgct aatattcaca tgtcgcgtac ctttctcgct cgcatgcggt
     4441 tatacgtcaa aatacgagaa atgccgccgc atgattatca aagtacgctt agcgactata
     4501 tcgtcgtgca atttgacggt gccggtagcg ttaacgaaga ccctactgcc caaaacctga
     4561 aatatcatat tactggtctg gaaaacattc gcgtgctgga ttgcagcgtc aatttttcca
     4621 tttcaccgga aacacaggtg attgattttg gtaaatttaa tttgctggat attcgtcgcc
     4681 acacaatgtc gaaaacattc agtattaaga cgacaaaatc acaaaatgac caatgcaccg
     4741 acggatttaa agtcagttcc tccttttata ccgaagaaac gttggttgaa gaagataaag
     4801 cattgttgat tggtaatggt ctgaagctac gtttgctgga tgaaaacgcc tcgccttata
     4861 ccttcaataa atatgctgaa tacgccgatt tcaccagcga tatgctgatc tacgaaaaaa
     4921 cctatacggc tgaactttcg tccattgcag gcacccccat cgaggctggc cccttcgata
     4981 cagtggtgct ttttaagatt aactataact gatttgccat gatgcccttt gcagccggaa
     5041 agggcatctc tttcagaaaa ttgctgattt tccccttttc cttgattgct gttatttttt
     5101 cctggcccgg ctttctttat gctgtatcga tacaccaaag agaaaataat gagggagcga
     5161 aggatgccag ttttgcagtg gggaatgtta tgtgtgctat cacttctcct ttctattggt
     5221 ttcctcgcgg tacatctccc ggcggcgcta ttacttgggc cgatgatcgc cgggatcatc
     5281 ttcagtatgc gcggaattac tctgcaactt ccccgctccg cttttctcgc cgcgcaggcc
     5341 attcttggct gcatgattgc gcaaaacctc actggttcga ttctcaccac gctggccgcc
     5401 aactggccga tcgtgcttgc tattttactg gtgacgctgc tttccagcgc catcgtgggt
     5461 tggttattgg tgcgctatag ctcactgcct ggaaataccg gtgcctgggg ttcttctcca
     5521 ggcggcgcag cggcaatggt cgctatggcg caagattacg gcgcagatat tcgcctggtg
     5581 gcgtttatgc aatatctgcg agtgctgttc gtcgcggggg ccgctgttct ggtcacccgc
     5641 atgatgctgg gtgataacgc tgaagcggtt aaccagcaaa tcgtctggtt cccgccagtg
     5701 agcattaatc tcctgcttac gattttgctc gcagtcgttg ccggtacggc gggatgcatg
     5761 ctgcgtcttc cttccggcac gatgctcatc ccgatgctgg cgggcgcagt gctccagtct
     5821 ggtcagctca tcaccatcga actaccggaa tggctgctgg cgatggcgta tatggcaatt
     5881 ggctggcgga ttggtcttgg tttcgataaa caaatcttac tgcgggcact acgcccgcta
     5941 ccgcaaatcc tgctgtcgat ttttgctctg ctggctattt gtgcgggtat ggcgtggggg
     6001 ctgacccggt ttatgcacat tgattttatg actgcctacc tcgccaccag tcccggcggg
     6061 cttgataccg tggcggtcat cgccgcaggg agcaatgccg atatggcgct tattatggcg
     6121 atgcaaaccc tgcgcctgtt cagtattttg ctgacggggc cagccattgc gcggtttatt
     6181 tcaacctatg cgccgaagcg gtcggcctag tgctggcagc ctggacacca gtaaaacggg
     6241 cgcgaggaca acgtggtttt ctcaatgatg ccgccacagc gttcgcacag ttcgccatca
     6301 cgatgaaaaa ccttaaagcg aaacagcgcc ccatgatgct tattctcatc cacctgcccc
     6361 cgcgtagcgt aagaaaaccg aggaatctcc agtaacgcgt gtgcgagtgc atccagttgc
     6421 gccgcattga gatctttcgc tttatgattt ccagtcaacc caacctgcca gaggatctcc
     6481 acccgcaaat aattgccaag cccagccaga aacgcctgat cgagcagtaa tcctgcaaac
     6541 tgacggttac gaaagcgcgg tgacaataac cgttccttta ccacctccgg cgtcagattc
     6601 ggatccagca catcgggacc aacgcgttgt aaaaacggat gcgtggtcag ttgttccggc
     6661 ctcaacatct caatatccga ggcgctataa agcagaatgg ttttgtcagc cgtttgcagt
     6721 tttacccgca atactcgcgt ggtctgcggc tcttcgccgg tatcaaccac gcgccagacg
     6781 ccgtaaagct gattatggct gtagagcgtt aagtcgttgg aaaaatgagt taacaacgcc
     6841 ttaccacgcg tttccacatg ggtaacgtgt tgaccgataa gttgtgattg ataagttttt
     6901 aactgcggga aggcaaacca gacatcagtt agtggtttgc ctttgatcgc cgcctccagg
     6961 ttatccgctg cacggcggat ctccgggcct tcaggcatgg tgatatcctt ttttcattct
     7021 ttattaatcg gggttatgct gcgacaacaa tctccttttc ggcaaatgta gagcgtagtc
     7081 ggcgggcgaa cgccagtgcg tgctcgccgt cgccatgcag gcagactgtt tgcgccgtga
     7141 ccgttgccca ttcgccggtg atacttttga ctctgccgtg ttgcaccatc tctagcgttt
     7201 gcgccagcgc ctgttcttcg ttttcaatca acgcgcctgg ctgacttcgc ggcaccagcg
     7261 agccgtcagc ctgataaccg cgatcggcaa acacttcctc gcgcgttgtc aggccatatt
     7321 gcttgcctgc acgaatcagc tcgcttcctg ccagcccaac gagaatcaat gccggatcgc
     7381 aagcgtatac cgctctggcg atggcgtctg ccagttgtgc ttctttcgcc gcctggttgt
     7441 acaacatgcc gtgcggtttg acatgacgca ttacgccgcc ttgcgcacgg gcaatcgttg
     7501 ccagcgcgcc aatttgatac agcgtctggg cgtaaacggt ttctggcggc aactgcatgg
     7561 cgctgcgacc aaaattttcc ctgtcgggaa aactcgggtg agcgccaatt gcaacaccat
     7621 tttttattgc ttcacgcacg caagcctgca tggtttgcgc atcgcctgca tgaaatccac
     7681 aggcaatatt ggcagaggaa accagcgtta atagctctgc gtcgctggcg cagccttcgc
     7741 ccagatcggc gttcaggtca attttcattg tgcagccgcc acgctaattg ttcaaaataa
     7801 cgttgctgat cttgccgcgc tttcagtgcc tcttccagtg aacactggac aaaatgaatc
     7861 ggctgaccga gcggaatttg cgcaagatgg tacatatcag cctcaatgat gcaggcaata
     7921 cgcgggtaac caccggtggt ctgtgcgtcg ttcatcaaca caatcggctg cccgttatgt
     7981 ggcacctgca ccacgcccgg taacaaaccg tgagataaca gttcgcgatc ggtggtgcgt
     8041 tttaaaattt gcccctgtaa gcgatagccc atgcggttac tttgcgagct aagctgccag
     8101 ggcgaacgcc agaatgcatc ctgcgaggca cgatcgaact catgatattc cggccccggc
     8161 aaggcgcgaa tgcggttgcc ccacagcagc tgtttaacgc cctgcgcttc cataaaatca
     8221 cgcttcgctt tgccaatcgg gagtcggtca ccatccttca gtaaacggcc ttccagcccg
     8281 ccaatcccca ctttgagatc ggtgctgcat gaccccatta ccggcggaac atcaatacca
     8341 cccgcgaccg ccagataact gcgcatcccg tgctgcgggc gtttaagcgt taaacgctgg
     8401 cctgctttca tcggcaatcg ccagccggtc cagacggcat tatcatccag ccgcgcttcg
     8461 caaccggcac ccgtcagagc aaaccaccca tcagtttcga actcaacagt taactgaccg
     8521 agcgtgatct ccagcgcggg ggcattggcg tcattaccca ccagtaggtt agcaatgcgt
     8581 aacgcgggca tatccagtgc gccgcagtgg ctgatacccg actggcgaaa accgtgacga
     8641 ccgccatcct gcacagtggt atacatgccc gcacgaataa tcttcagcat actccctcct
     8701 tctgcggtac aaagcgcacg ctgtctcccg gacgtaataa gatgggttcg tcacgcgccg
     8761 gatcaaacag gctgagtgag gtatgaccaa tcaactgcca gccacccggc gttgccagcg
     8821 gataaacacc agtctgcggc ccgccgatcc cgacagaacc tgccggaacg agtaagcgcg
     8881 gttcagcgcg ccgtggcgtg tgtagttgtt ccggcaaact cccgagatac gggaagcccg
     8941 gttgaaaacc taaaaaccag accacgtatt ccacggagga gtgcaattca acaacctgtt
     9001 tttcgctcaa cccgcaatgc gccgcgacca ccgccaaatc cggtccgcct gcaccaccgt
     9061 aaaccaccgg aatttcaata aagcgagact caggttccag ggcctcgctc tcctcccacc
     9121 agcgttgcaa acgctctatg gcatccagcg ccagcgactc aggattacgc aaaatcaccg
     9181 taatattgtt catgccggga atggcttcaa ccacattcgg catatccacc agacgctgcg
     9241 ccagtcgcca gatccgtttc tggctagcca gcgtcaccgg cggttccagt tccagcacta
     9301 ccgccgtttc acctatcaga taacaacgcg ctcgttgcac tttcgatccc tctgattatt
     9361 cgttatgcag gattaggaat atcaataaag gtcacatcaa gatcggtatt ttcattcagc
     9421 cactcgctca atgcgcgaat accaccacgt tcagtggcat ggtgacctgc agcataaaaa
     9481 tgcaatccct gctcgcgggc tgaatgaatg gtctgttcag aaacttcgcc agtaataaaa
     9541 gcatccacgc caaaacgcgc ggcgctatcg ataaaacttt gcccgccgcc cgtgcaccag
     9601 gcgacgcgct ggaccacctc aggtccggta tcgccacacc ataacggctt acgtcccaga
     9661 cgcgcttcaa tccaggaggc tagttccagt cccggcacag gcatggtcag ctctccccac
     9721 ggcaccaacg gctcaatttc gcccatgacc gtgatcccca gtaacgccgc cagctgtgcg
     9781 ttattgccca gctcaggatg tgcgtcaagc ggcaaatgcc agccatacag gttgatatca
     9841 ttcgccagca acgtttttaa acggttacgc ttcattccgc gaatgaccgg agactctcct
     9901 ttccagaagt agccatgatg cacaatgacc gcatccgcgc ccagacgcac tgcctcatcg
     9961 agcaaagcct ggctggcggt gacaccggta acaatttttt gcaccgtctc tttgccttcc
    10021 acctgcaaac cattcggcgc gtaatcacta atcgccgcgc tgttcagttt ttcgttaatc
    10081 agttgttcca gttcggtgtt tttcatcttc gcgccttccg tattctgata gctacaccgt
    10141 taacatagcg ttacctcgcc agttcgtcga tagccaatct tttgacatat taagaaacaa
    10201 acccgacgcc aaaagacgca aattgtttat atcatcacgc ttcagctaat gtatatttat
    10261 gcaatcagac agcatattgc ataaataatc agatctgtat caaagtttta actttaagga
    10321 aacacaagca cgccgcgcaa ctattacgtg acgttgccgt caattgtgga attattatga
    10381 ataaacacgc atcacagccg cgcgctattt actatgtcgt tgcgctgcaa atctgggaat
    10441 attttagctt ttacggcatg cgtgccctgc tgattctcta tctcaccaat caactaaaat
    10501 acaacgatac tcacgcctac gagttattta gcgcctactg ttcgctggtg tatgtcacgc
    10561 caatcctcgg tggctttttg gcggataaag ttctcggcaa tcgcatggcg gtgatgctgg
    10621 gggcgttatt gatggcgatc ggtcatgtgg tgttgggtgc cagtgagatc catccgtcat
    10681 tcctctatct gtccctggcg ataatcgttt gtggctatgg tctgtttaaa tccaatgtca
    10741 gttgcctgct cggcgagctg tatgagccaa ccgatccgcg tcgtgatggc ggtttctcgc
    10801 tgatgtatgc ggcgggtaac gtggggtcta ttatcgcacc tatcgcctgt ggttacgccc
    10861 aggaagagta cagctgggcg atgggctttg gcctggcggc ggttggcatg atcgcgggtc
    10921 tggtcatttt cttatgtggc aatcgtcatt tcactcatac ccgcggcgtt aataaaaaag
    10981 tactgcgtgc gacaaacttt ctcctgccta actggggatg gctgctggtt ctgctggtgg
    11041 caacgcctgc gctgattacc gtattgttct ggaaagagtg gtcggtatac gccttaattg
    11101 tcgcgactat tattggcctg ggtgtactgg caaaaattta tcgcaaagca gaaaaccaga
    11161 aacagcgtaa ggagctgggg ctgattgtga cgctcacctt cttcagtatg ttgttctggg
    11221 ccttcgcaca acagggcggc agctcgatta gcctttatat cgaccgcttc gttaaccgcg
    11281 atatgtttgg ttataccgtt ccgactgcta tgttccagtc gattaatgcc ttcgcagtta
    11341 tgctgtgcgg tgtgttcctg gcgtgggtgg ttaaagaaag cgtcgcaggt aatcgtaccg
    11401 tgcgcatctg gggaaaattt gctcttggtc tcggcctgat gagcgccggg ttctgcattc
    11461 tgaccttaag cgcccgctgg tccgcaatgt atggtcactc ttctctgcca ctgatggtat
    11521 taggcctggc ggtgatgggc tttgcggaac tgtttatcga cccggttgcc atgtcgcaaa
    11581 ttacgcgcat tgaaattccg ggcgtgaccg gcgtattaac cggcatctac atgctgcttt
    11641 ctggcgcgat cgcgaactat ctggcgggcg tgattgccga tcagacatcg caggcttcgt
    11701 ttgatgcttc cggggcgatc aactactcca tcaatgcata tattgaagta tttgatcaaa
    11761 ttacctgggg cgcactggcg tgtgtaggac tggtactgat gatttggctg tatcaggcgc
    11821 tgaaattcag aaaccgcgcg ctggcgctgg agtcataata ggccagcacc atacctgata
    11881 aaacgctcgc tgcgttttat caggctcctt tcctcgcttc ttcgtacgct gccagcgttc
    11941 gcagccttgc ctctttgtga tcaactatcg gttgcggata atccagcttc acacctgctt
    12001 tctgcgccca cttccacggc tcatgcaccg ctttccctgg tacatcgcgc agctccggta
    12061 accatcgacg aataaactcg ccctcacggt caaatttctc gccctgagtt atcggattga
    12121 aaatacgaaa atacggcgca gcatcagtac ccgtagaagc cgcccactgc cagccaccgt
    12181 tattagctgc caaatcacca tcaatcagct gcgacatgaa atatcgctcg ccttcgcgcc
    12241 agtcgatcaa caaatctttc accagaaaac tggctgtaat catccgtagc cggttatgca
    12301 tccagccagt gctgttaagc tgacgcatag cggcatcaac aatcgggtat cccgttttgc
    12361 ctttctgcca ggcctgtaaa tgtgcgggat tgctttgcca ctgcacacga tccgtccagg
    12421 caataaatgg acgatgttta cacaacgagg ggtaatacgt catcagatga cggtagaact
    12481 cgcgccagat cagctcacta agccagacac taccggcccc accgtccagc gcctgcggct
    12541 gttcagccaa caagcgatgc aagcactggc gaggcgataa cccgcccgtt gccaggctgg
    12601 ccgacaaacg gctggtgcct tccactgccg gaaaatctcg ttgttgctca taatctccgg
    12661 caccgttctg gcaaaactgg cgtaattgcg caatcgccgc tttttcttcc accggaaaat
    12721 gcgcagtatc gaaagactga cgaggataat tcagcgtaat ggatggcgag ggctctatcg
    12781 atccgctact acgaactttt ggtgcagcga cgcactccgg catcccttcc cgcagccgtt
    12841 tcagccaggc attcttaaaa ggcgtaaaga ctttgtacat ctcgtgattg ccggtcatca
    12901 ccgcgccagg cggcaggatc acgctgtcat caaatccttc acacaccacg ttacgcagcg
    12961 ctctttcaac ttccacatcc cgcgcccgct cattcacttc atactgatag ttataaaaca
    13021 ggtgggtaac gctgttttcc gcgcacacct gtttaactat ttcgacactg gcgacaaagt
    13081 catccacttc acggaacaat aaaggaatac ctttttccgc aagcgctatt tgtagcccat
    13141 tcagttgagc attgataagt tcagcctgac gcggcgacat gttatgcgtc tcccactggc
    13201 gtggtgtagc gatatacagc gccagcacgc gtgcagacga attgcggcag gcggcagcaa
    13261 gcgcgagatt atcatgcaga cgtaaatcct ggcgaaacca gaccagatgg gtagtcataa
    13321 aactcctgaa tggcgcaagt taatcacacg cggccaaagt tcgaaataac gctgccctga
    13381 aagccaggcg tcaggataaa gcgccatata gtgtttgata cgcatcagcg gcgcaagaag
    13441 cggttgctcg ccacggcgat aactgtcgat aagcgcagcc agctgctggc gttctgtgga
    13501 atcaatatgt gggcgaaaat aaccctgaac gtgcatcaaa acgttggtgt gatcgcgcgt
    13561 gttggcgggg tgagaaagta aaacgattac gcgttggcgg tactggttgt aatagtcatc
    13621 cagattttgc caccgatgaa tatcagccac aaacgggcca agtttgcggt attccggctg
    13681 agaatgcgcc agaaagacga gtttatagcg gctgtgataa tcgagaagcg ccccgcgcgt
    13741 taagccatgt tctttcagtc gatataactc atgaagcgcg aagatacgga ttagggtgct
    13801 gtcatcaaat cgttgctgat tcattactgc tcctgaacgg tttacaggag taagtgtaga
    13861 cgttgagaaa tgatatttgt gaagttaatc ctgttgtagc aggacaaatt tacgaaagcc
    13921 tgctccccgc aaggactgac gtcaggtagt ttctaaccat agctgccctt tctattcaaa
    13981 cgtgaaatca ataagctcat cagggacatc gcaaacaata tgaagacggg tttcttctct
    14041 gccgtgactc ttttcactaa ttgcgtaact gtcatgctct ggattattta attctttcag
    14101 cggaaatttt tcctcaaagg ctttatttag ccgcccct
//
LOCUS       DAPGUL010000115        14127 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.117, whole genome shotgun sequence.
ACCESSION   DAPGUL010000115 DAPGUL010000000
VERSION     DAPGUL010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14127)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14127)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14127
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.117"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            162..1220
                     /gene="citC"
                     /locus_tag="RHX21_003700"
     CDS             162..1220
                     /gene="citC"
                     /locus_tag="RHX21_003700"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415151.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HDV1988825.1"
                     /translation="MFGNDIFTRVKRSENKKMAEIAQFLHENDLSVDTTVEVFITVTR
                     DEKLIACGGIAGNIIKCVAISESVRGEGLALTLATELINLAYERHSTHLFIYTKTEYE
                     ALFRQCGFSTLTCVPGVMVLMENSATRLKRYAESLKKFRHPGNKIGCIVMNANPFTNG
                     HRYLIQQAAAQCDWLHLFLVKEDSSRFPYEDRLDLVLKGTADIPRLTVHRGSEYIISR
                     ATFPCYFIKEQSVINHCYTEIDLKIFRQYLAPALGVTHRFVGTEPFCRVTAQYNQDMR
                     YWLETPTISAPPIELVEIERLRYQEMPISASRVRQLLAKNDLTAIAPLVPAVTLHYLQ
                     NLLEHSRQDAAARQKTPA"
     gene            1235..1531
                     /gene="citD"
                     /locus_tag="RHX21_003701"
     CDS             1235..1531
                     /gene="citD"
                     /locus_tag="RHX21_003701"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HDV1988826.1"
                     /translation="MKINQPAVAGTLESGDVMIRIAPLDTQDIDLQINSSVEKQFGDA
                     IRTTILDVLARYNVRGVQLNVDDKGALDCILRARLEALLARASGIPALPWEDCQ"
     gene            1528..2436
                     /gene="citE"
                     /locus_tag="RHX21_003702"
     CDS             1528..2436
                     /gene="citE"
                     /locus_tag="RHX21_003702"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415149.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HDV1988827.1"
                     /translation="MISASLQQRKTRTRRSMLFVPGANAAMVSNSFIYPADALMFDLE
                     DSVALREKDTARRMVYHALQHPLYRDIETIVRVNALDSEWGVNDLEAVVRGGADVVRL
                     PKTDTAQDVLDIEKEILRIEKACGREPGSTGLLAAIESPLGITRAVEIAHASERLIGI
                     ALGAEDYVRNLRTERSPEGTELLFARCSILQAARSAGIQAFDTVYSDANNEAGFLQEA
                     AHIKQLGFDGKSLINPRQIDLLHNLYAPTQKEVDHARRVVEAAEAAAREGLGVVSLNG
                     KMVDGPVIDRARLVLSRAELSGIREE"
     gene            2447..3979
                     /gene="citF"
                     /locus_tag="RHX21_003703"
     CDS             2447..3979
                     /gene="citF"
                     /locus_tag="RHX21_003703"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HDV1988828.1"
                     /translation="MTQKIEQSQRQERVAAWNRRAECDLAAFQNSPKQTYQAEKARDR
                     KLCANLEEAIRRSGLQDGMTVSFHHAFRGGDLTVNMVMDVIAKMGFKNLTLASSSLSD
                     CHAPLVEHIRQGVVTRIYTSGLRGPLAEEISRGLLAEPVQIHSHGGRVHLVQSGELNI
                     DVAFLGVPSCDEFGNANGYTGKACCGSLGYAMVDADNAKQVVMLTEELLPYPHNPASI
                     EQDQVDLIVKVDRVGDAAKIGAGATRMTTNPRELLIARSAADVIVNSGYFKEGFSMQT
                     GTGGASLAVTRFLEDKMRSRDIRADFALGGITATMVDLHEKGLIRKLLDVQSFDSHAA
                     QSLARNPNHIEISANQYANWGSKGASVDRLDVVVLSALEIDTQFNVNVLTGSDGVLRG
                     ASGGHCDTAIASALSIIVAPLVRGRIPTLVDNVLTCITPGSSVDILVTDHGIAVNPAR
                     PELAERLQEAGIKVVSIEWLRERARLLTGEPQPIEFTDRVVAVVRYRDGSVIDVVHQV
                     KE"
     gene            3983..4534
                     /gene="citX"
                     /locus_tag="RHX21_003704"
     CDS             3983..4534
                     /gene="citX"
                     /locus_tag="RHX21_003704"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HDV1988829.1"
                     /translation="MHLLPELASHHAVSIPELLVSRDERQARQHVWLKRHPVPLVSFT
                     VVAPGPIKDSEVTRRIFNHGVTALRALAAKQGWQIQEQAALVSASGPEGMLSIAAPAR
                     DLKLATIELEHSHPLGRLWDIDVLTPEGEILSRRDYSLPPRSCLLCEQSAAVCARGKT
                     HQLTDLLNRMEALLNDVDACNVN"
     gene            4509..5387
                     /gene="citG"
                     /locus_tag="RHX21_003705"
     CDS             4509..5387
                     /gene="citG"
                     /locus_tag="RHX21_003705"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HDV1988830.1"
                     /translation="MSMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDR
                     INCGAHKDMALEDFHRSALAIQGWLPRFIEFGACSAEMAPEAVLHGLRPIGMACEGDM
                     FRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTN
                     NSQLTAGQRLYQQLGLTGARGEAEAGYPLVLNHALPHYLTLLDQGLDPELALLDTLLL
                     LMAINGDTNVASRGGEGGLRWLQREAQTLLQKGGIRTPADLDYLRQFDRECIERNLSP
                     GGSADLLILTWFLAQI"
     gene            5438..6901
                     /gene="citT"
                     /locus_tag="RHX21_003706"
     CDS             5438..6901
                     /gene="citT"
                     /locus_tag="RHX21_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate/succinate antiporter CitT"
                     /protein_id="HDV1988831.1"
                     /translation="MSLAKDNIWKLLAPLVVMGVMFLIPVPDGMPPQAWHYFAVFVAM
                     IVGMILEPIPATAISFIAVTICVIGSNYLLFDAKELADPAFNAQKQALKWGLAGFSST
                     TVWLVFGAFIFALGYEVSGLGRRIALFLVKFMGKRTLTLGYAIVIIDILLAPFTPSNT
                     ARTGGTVFPVIKNLPPLFKSFPNDPSARRIGGYLMWMMVISTSLSSSMFVTGAAPNVL
                     GLEFVSKIAGIQISWLQWFLCFLPVGVILLIIAPWLSYVLYKPEITHSEEVATWAGDE
                     LKTMGALTRREWTLIGLVLLSLGLWVFGSEVINATAVGLLAVSLMLALHVVPWKDITR
                     YNSAWNTLVNLATLVVMANGLTRSGFIDWFAGTMSTHLEGFSPNATVIVLVLVFYFAH
                     YLFASLSAHTATMLPVILAVGKGIPGVPMEQLCILLVLSIGIMGCLTPYATGPGVIIY
                     GCGYVKSKDYWRLGAIFGVIYISMLLLVGWPILAMWN"
     gene            7015..7821
                     /gene="rna"
                     /locus_tag="RHX21_003707"
     CDS             7015..7821
                     /gene="rna"
                     /locus_tag="RHX21_003707"
                     /EC_number="4.6.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease I"
                     /protein_id="HDV1988832.1"
                     /translation="MKAFWRNAALLAVSLLPFSSANAVALQAKQYGDFDRYVLALSWQ
                     TGFCQSQHDRNRNERDECRLQTETTNKADFLTVHGLWPGLPKSVAARGVDERRWMRFG
                     CATRPIPNLPEAHASRMCSSPETGLSLETAAKLSEVMPGAGGRSCLERYEYAKHGACF
                     GFDPDAYFGTMVRLNQEIKESEAGKFLADNYGKTVSRRDFDAAFAKSWGKENVKAVKL
                     TCQGNPAYLTEIQISIKADAINAPLSANSFLPQPHPGNCGKTFVIDKVGY"
     gene            8051..8461
                     /gene="rnk"
                     /locus_tag="RHX21_003708"
     CDS             8051..8461
                     /gene="rnk"
                     /locus_tag="RHX21_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside diphosphate kinase regulator"
                     /protein_id="HDV1988833.1"
                     /translation="MSRPTIIINDLDAERIDILLEQPAYAGLPIADALNAELDRAQMC
                     SPEEMPHDVVTMNSRVKFRNLSDGEVRVRTLVYPAKMTDSNTQLSVMAPVGAALLGLR
                     VGDSIHWELPGGVATHLEVLELEYQPEAAGDYLL"
     gene            complement(8692..9930)
                     /locus_tag="RHX21_003709"
     CDS             complement(8692..9930)
                     /locus_tag="RHX21_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent formaldehyde
                     dehydrogenase"
                     /protein_id="HDV1988834.1"
                     /translation="MKALTYHGPHHVQVENVPDPGIEQADDIILRITATAICGSDLHL
                     YRGKIPQVKHGDIFGHEFMGEVVETGKDVKNLQKGDRVVIPFVIACGDCFFCRMQQYA
                     ACENTNAGKGAALNKKQIPAPAALFGYSHLYGGVPGGQAEYVRVPKGNVGPFKVPPLL
                     SDDKALFLSDILPTAWQAAKNAQIQQGSSVAVYGAGPVGLLTIACARLLGAEQIFVVD
                     HHPYRLRFAADRYGAIPINFDEDSDPAQSIIEQTAGHRGVDAVIDAVGFEAKGSTTET
                     VLTNLKLEGSSGKALRQCIAAVRRGGIVSVPGVYAGFIHGFLFGDAFDKGLTFKMGQT
                     HVHAWLGELLPLIEKGLLKPEEIVTHYMPFEEAARGYEIFEKREEECRKVILVPGAQS
                     AEAAQKAVSGLVNAMPGGTI"
     gene            10151..10579
                     /gene="uspG"
                     /locus_tag="RHX21_003710"
     CDS             10151..10579
                     /gene="uspG"
                     /locus_tag="RHX21_003710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspG"
                     /protein_id="HDV1988835.1"
                     /translation="MYKTIIMPVDVFEMELSDKAVRHAEFLAQDDGVIHLLHVLPGSA
                     SLSLHRFAADVRRFEEHLQHEAEERLQTMVSHFTIDPSRIKQHVRFGSVRDEVNELAE
                     ELGADVVVIGSRNPSISTHLLGSNASSVIRHANLPVLVVR"
     gene            complement(10700..12265)
                     /gene="ahpF"
                     /locus_tag="RHX21_003711"
     CDS             complement(10700..12265)
                     /gene="ahpF"
                     /locus_tag="RHX21_003711"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017455864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HDV1988836.1"
                     /translation="MLDTNMKTQLKAYLEKLTKPVELIATLDDSAKSAEIKELLAEIA
                     ELSDKVTFKEDNSLPVRKPSFLITNPGSNQGPRFAGSPLGHEFTSLVLALLWTGGHPS
                     KEAQSLLEQIRHIDGDFEFETYYSLSCHNCPDVVQALNLMSVLNPRIKHTAIDGGTFQ
                     NEITDRNVMGVPAVFVNGKEFGQGRMTLTEIVAKIDTGAEKRAAEELNKRDAYDVLIV
                     GSGPAGAAAAIYSARKGIRTGLMGERFGGQILDTVDIENYISVPKTEGQKLAGALKVH
                     VDEYDVDVIDSQSASKLIPAAVEGGLHQIETASGAVLKARSIIVATGAKWRNMNVPGE
                     DQYRTKGVTYCPHCDGPLFKGKRVAVIGGGNSGVEAAIDLAGIVEHVTLLEFAPEMKA
                     DQVLQDKLRSLKNVDIILNAQTTEVKGDGSKVVGLEYRDRVSGDIHNIELAGIFVQIG
                     LLPNTNWLEGAVERNRMGEIIIDAKCETNVKGVFAAGDCTTVPYKQIIIATGEGAKAS
                     LSAFDYLIRTKTA"
     gene            complement(12394..12957)
                     /gene="ahpC"
                     /locus_tag="RHX21_003712"
     CDS             complement(12394..12957)
                     /gene="ahpC"
                     /locus_tag="RHX21_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003858764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HDV1988837.1"
                     /translation="MSLINTKIKPFKNQAFKNGEFIEITEKDTEGRWSVFFFYPADFT
                     FVCPTELGDVADHYEELQKLGVDVYAVSTDTHFTHKAWHSSSETIAKIKYAMIGDPTG
                     ALTRNFDNMREDEGLADRATFVVDPQGIIQAIEVTAEGIGRDASDLLRKIKAAQYVAS
                     HPGEVCPAKWKEGEATLAPSLDLVGKI"
     gene            13329..14075
                     /gene="dsbG"
                     /locus_tag="RHX21_003713"
     CDS             13329..14075
                     /gene="dsbG"
                     /locus_tag="RHX21_003713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308670.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbG"
                     /protein_id="HDV1988838.1"
                     /translation="MLKKILLLALLPAIAFAEELPSPVKAIEKQGITIIKTFDAPGGM
                     KGYLGKYQDMGVTIYLTPDGKHAISGYMYNEKGENLSNTLIEKEIYAPAGREMWQRME
                     QSHWLLDGKKDAPVIVYVFADPFCPYCKQFWQQARPWVDSGKVQLRTLLVGVIKPESP
                     ATAAAILASKDPAKTWQEYESSGGKLKLNVPANVSTEQMKVLSANEKLMDDLGANVTP
                     AIYYMSKENTLQQAVGLPDQKTLNIIMGNK"
BASE COUNT         3345 a         3745 c         3558 g         3479 t
ORIGIN      
        1 cacgccgaaa tactccttag gatgtatagc gaaaggagaa aaagatatac ctcgatcacc
       61 cccctttctc ccaagtgaaa ataaaaggtt atcagtttgc aacattgaac aacattcgtt
      121 gcaaatcgat aacaacatgc accttcagga tactatttat tatgttcggc aatgatattt
      181 tcacccgcgt aaaacgttca gaaaataaaa aaatggcgga aatcgcccaa ttcctgcatg
      241 aaaatgattt gagcgttgac accacagtcg aagtatttat taccgtaacc cgcgatgaaa
      301 agcttatcgc gtgcggtgga attgccggaa atattattaa atgcgttgct atcagtgaat
      361 ccgttcgcgg tgaaggactg gcgctgacat tagccactga actgataaac ctcgcctatg
      421 agcggcacag cacgcatctg tttatttata ccaaaaccga atacgaggcg ctgttccgcc
      481 agtgcggttt ttccacgctg acctgcgtac ccggcgtgat ggtgctgatg gaaaacagcg
      541 ccacgcgact gaaacgctat gccgaatcgc tgaaaaaatt tcgtcatcca gggaacaaga
      601 ttggctgcat tgtgatgaac gccaatccct tcacgaatgg tcaccgttat ctgattcaac
      661 aagctgcggc acagtgcgac tggttgcatc tgtttttagt caaagaagat tcttcacgct
      721 tcccctatga agaccggttg gatctggtgt taaaaggcac cgccgatatt ccacgcctga
      781 ctgtgcatcg cggctccgaa tacatcatct cccgcgctac gttcccttgc tacttcatta
      841 aagaacagag cgtcattaac cattgttaca ccgaaattga tctgaagatt ttccgtcagt
      901 acctcgctcc cgcgctgggt gtaactcacc gctttgtcgg tactgaaccc ttttgtcgcg
      961 ttaccgccca gtacaaccag gatatgcgct actggctgga aacgccgact atctccgcac
     1021 cgcccatcga actggttgaa attgagcggc tgcgttacca ggagatgccg atatccgctt
     1081 cccgggtacg tcaactgctg gcgaaaaacg atctcacggc tatcgcgccg ctggtccctg
     1141 cagtcacgct gcattatttg cagaacctgc ttgagcactc ccgccaggac gcggcagctc
     1201 gtcaaaagac ccccgcatga gaaacaggtg aaaaatgaaa ataaaccagc ccgccgttgc
     1261 aggcaccctt gagtctgggg atgtgatgat acgcatcgcc ccactcgata cgcaggatat
     1321 cgacctgcaa atcaatagca gcgttgagaa acagtttggc gatgcaattc gcaccaccat
     1381 tctggacgtt ctcgcccgct acaacgtgcg cggcgtacag ctgaatgtcg atgacaaagg
     1441 cgcactggac tgcattttac gtgcacgact ggaagccctg ctggcacgcg ccagcggtat
     1501 cccggctctg ccatgggagg attgccaatg atttccgctt cgctgcaaca acgtaaaact
     1561 cgcacccgcc gcagcatgtt gtttgtgcct ggtgccaatg ccgcgatggt cagcaactcc
     1621 ttcatctacc cggctgatgc cctgatgttt gacctcgaag actccgtagc attgcgtgaa
     1681 aaagacaccg cccgccgcat ggtttaccac gcgctgcaac atccgctgta tcgcgatatt
     1741 gaaaccattg tgcgtgtcaa cgcgctggat tccgaatggg gtgtcaacga cctggaagcc
     1801 gtcgttcgcg gtggtgcgga cgttgtgcgt ctgccgaaaa ccgataccgc tcaggatgtt
     1861 ctggatatcg aaaaagagat cctgcgtatc gaaaaagcct gtggtcgtga acccggcagc
     1921 accggcctgc tggcggcgat tgaatctccg ctgggcatta cccgcgcagt ggaaatcgct
     1981 cacgcttccg agcgtttgat cggtatcgcc ctcggtgcag aagactatgt gcgcaacctg
     2041 cgtacagaac gctccccgga aggaactgaa ctgctgttcg cacgctgttc cattttgcag
     2101 gccgcgcgct ctgcgggtat tcaggcgttc gataccgtct attccgacgc taacaacgaa
     2161 gccggattcc tgcaagaagc cgcccacatc aaacagctgg gctttgacgg caaatcgctg
     2221 atcaacccgc gtcagattga tctgttgcac aacctctacg caccaaccca gaaagaagtg
     2281 gatcacgccc gccgcgtcgt agaagccgct gaagccgccg ctcgcgaagg cctcggcgtg
     2341 gtttccctga acggcaagat ggtggacggt ccggttatcg atcgcgcccg tctggtgctc
     2401 tctcgtgcag aactttccgg catccgcgaa gaataaggca atcaaaatga cgcagaaaat
     2461 tgaacaatct caacgacaag aacgggtagc ggcctggaat cgtcgcgctg aatgcgatct
     2521 tgccgctttc cagaactcgc caaagcaaac ctaccaggct gaaaaagcgc gcgatcgcaa
     2581 actgtgcgcc aacctggaag aagcgattcg tcgctctggt ttacaggacg gcatgacggt
     2641 ttccttccat cacgctttcc gtggcggtga cctgaccgtc aatatggtga tggacgtcat
     2701 cgcgaagatg ggctttaaaa acctgaccct ggcgtccagc tccctgagtg attgccatgc
     2761 gccgctggta gaacacattc gccagggcgt ggttacccgc atttatacct ctggcctacg
     2821 tggtccactg gcggaagaaa tctcccgcgg tctgctggcg gaaccggtgc aaatccactc
     2881 tcacggcggt cgtgtgcatc tggtacagag cggcgaactg aatatcgatg tggctttcct
     2941 cggcgtcccg tcctgtgatg aattcggtaa tgccaacggc tacaccggta aagcctgctg
     3001 cggctccctc ggctatgcaa tggttgatgc cgacaacgca aaacaggttg tgatgcttac
     3061 cgaagaactg ctgccttatc cgcataatcc ggcaagcatt gagcaagatc aggttgattt
     3121 aatcgtcaaa gttgatcgcg ttggcgatgc tgcaaaaatc ggcgctggtg ctacccgtat
     3181 gaccactaac ccgcgcgaac tgcttattgc ccgtagcgct gcggatgtga ttgtcaactc
     3241 aggctacttc aaagaaggtt tctccatgca aaccggcacc ggcggcgcat cgctggcggt
     3301 aacccgtttc ctggaagaca aaatgcgtag ccgcgatatt cgcgccgact tcgccctcgg
     3361 tggtattacc gcgacgatgg ttgatctgca cgaaaaaggt ctgatccgca aactgctgga
     3421 tgtacagagc tttgacagcc acgctgcgca atcgctggcc cgtaacccca atcacatcga
     3481 aatcagcgcc aaccagtacg ctaactgggg ttcgaaaggc gcatcggttg atcgtctcga
     3541 cgtggtggta ctgagcgcgc tggaaattga cacccagttc aacgttaacg tgctgaccgg
     3601 ctctgacggc gtactgcgtg gtgcttccgg tggtcactgc gataccgcga ttgcctctgc
     3661 gctttccatc atcgtcgcgc cgctggtacg cggtcgtatt ccgactctgg tggataacgt
     3721 gctgacctgc atcaccccgg gctccagtgt cgatattctg gtcacagacc acggtatcgc
     3781 agttaacccg gcacgtccgg agctggcaga acgtctgcag gaagcgggca ttaaagtggt
     3841 ttccattgag tggctgcgtg aacgtgcgcg tctgctgacc ggtgaaccac agccgattga
     3901 attcaccgac cgcgtcgttg ccgttgtgcg ttaccgcgat ggctcggtga tcgatgttgt
     3961 acatcaggtg aaggaataag ccatgcacct gcttcctgaa ctcgccagcc accatgcggt
     4021 gtcaattccc gagctgctcg tcagccggga tgaaaggcaa gcacggcaac acgtctggct
     4081 caagcgtcat cctgttccac tggtctcctt taccgtggtt gcgcctgggc cgattaaaga
     4141 cagtgaggtc acacgccgaa tttttaatca tggcgtgaca gccttgcgtg ccttagccgc
     4201 aaaacagggc tggcaaattc aggagcaggc tgcactggtt tccgccagcg ggccggaggg
     4261 tatgttgagc attgccgccc cggctcgcga cctcaagctc gccaccattg agcttgaaca
     4321 tagtcatcct ctcgggcggt tatgggatat cgatgtcctg acgcccgaag gcgaaattct
     4381 ctcccgccgc gactattcac tgccgcctcg cagctgcctg ttgtgcgagc aaagcgcagc
     4441 cgtctgcgcg cgtggaaaaa cccatcaact gaccgattta ctcaaccgca tggaggcact
     4501 gctgaacgat gtcgatgcct gcaacgtcaa ctaaaaccac aaagcttgcg acgtcattaa
     4561 tcgatgagta cgccctgctg ggctggcgcg ccatgctgac tgaagtcaat ctgtcaccga
     4621 aaccaggcct cgtggatcgg attaactgcg gtgcgcataa agatatggcg ctggaagatt
     4681 tccaccgcag cgcgctggcg attcagggct ggctaccccg tttcattgaa tttggtgcct
     4741 gtagtgcgga aatggcacca gaagcggtac tccacggatt acgcccaatt ggtatggctt
     4801 gcgaaggtga tatgttccgc gccactgcgg gcgtaaacac gcataaaggc agcatttttt
     4861 ctttagggct gctatgtgcg gcaattggcc gtttgcttca gctcaaccag ccggtaacgc
     4921 caacaaccgt ttgttctacg gcggcaagtt tctgccgtgg tctgaccgat cgcgaactgc
     4981 gtaccaataa ttcacaactg acggcaggtc aacggttgta ccagcagctt ggccttaccg
     5041 gcgcacgcgg tgaagccgaa gcgggttatc cactagtgct caaccacgcc ctgccgcatt
     5101 acctcactct gctggatcag gggttagatc ctgaactggc attgctcgat accttgctcc
     5161 tactgatggc gatcaacggc gataccaacg ttgcatcgcg cggtggcgag gggggcctgc
     5221 gctggctaca gcgcgaggcg caaacattat tgcaaaaagg gggcattcga acccccgccg
     5281 atctcgatta tctccggcag ttcgacaggg agtgtatcga acgaaatctc agtccaggcg
     5341 gcagtgccga cctgctgatc cttacctggt ttttagcaca gatttaatta tttaagcact
     5401 tgataaattt ggaaatatta attttcggag aacccgtatg tctttagcaa aagataatat
     5461 atggaaacta ttggccccac tggtggtgat gggtgtcatg tttcttatcc ctgtccccga
     5521 cggtatgccg ccgcaggcat ggcattactt cgctgtgttt gtggcaatga ttgtcggcat
     5581 gatcctcgag ccaattccgg caacagcgat cagttttatt gcggttacta tttgcgttat
     5641 tggcagtaat tacctgctct ttgatgccaa agaattagct gacccagcgt ttaatgcgca
     5701 aaaacaggcg ctgaaatggg gtctggctgg tttttccagc accacggtat ggctggtatt
     5761 tggcgcattt atttttgcat tagggtatga agtttccggg ttaggtcgtc gcattgccct
     5821 tttcctggtg aaattcatgg gcaaacgcac gctgacgttg ggttatgcga ttgtcattat
     5881 cgacattctg ctggcaccgt ttacaccgtc caacaccgcg cgtaccgggg gtacggtttt
     5941 tccggtcatt aaaaacctgc cgccgctgtt taaatcattc cccaacgatc cgtccgcgcg
     6001 tcgtattggc ggctatttga tgtggatgat ggtcattagt accagtctga gttcgtccat
     6061 gtttgtcacc ggtgcggcac caaacgtgct gggtctggag ttcgtcagca aaattgccgg
     6121 tatccagatt agctggttgc agtggttcct ctgcttcctg ccggttgggg ttatcttgct
     6181 tatcattgcg ccgtggcttt cctacgtgct gtacaaaccg gaaatcacac acagtgaaga
     6241 agtggcaacc tgggcgggtg atgaactgaa aaccatgggt gcgctgacac gcagagagtg
     6301 gacactgatt ggccttgtat tgctcagctt aggtttgtgg gtttttggca gtgaagtcat
     6361 taatgctact gcagttggtc tgctggcagt ttcgctaatg ctggccctgc acgttgtgcc
     6421 ttggaaagat attacccgct ataacagcgc atggaacacg ctggtcaacc tggcaactct
     6481 ggttgtgatg gctaacggcc tgactcgttc tggttttatt gactggttcg ccggtaccat
     6541 gagtacgcac ctggaaggat tctcaccaaa cgcaacggtg attgtactgg ttctggtgtt
     6601 ctactttgca cactacctgt ttgccagcct gtctgcgcac accgcaacca tgctgccggt
     6661 tattctggcc gttggtaaag gtattccggg cgtaccaatg gaacaactgt gtatcctgct
     6721 ggtgctgtct atcggtatca tgggctgtct gacgccgtat gcaaccggtc ctggggtgat
     6781 tatttacggc tgtggctatg tgaaatcaaa agattactgg cgtcttggcg caatcttcgg
     6841 ggtgatttac atctctatgt tgctgttggt tggctggccg attctcgcca tgtggaacta
     6901 atacgttcgc caaacgctga ataaatcatc acgcccgcca ggtaagccca cctggcgggc
     6961 ttttttatga tttaatagat agtattcagt gtatgtatga gttccacacc cattatgaaa
     7021 gcattctggc gtaatgccgc gttgctcgcg gtttctctgc ttcccttctc ttctgccaac
     7081 gccgtagcgt tgcaggcaaa acagtatggc gattttgatc gctatgtcct ggccctctcc
     7141 tggcaaaccg gattttgcca gagtcaacac gatcgaaatc gtaacgaacg agatgaatgt
     7201 cgcctgcaaa ccgaaacgac caacaaagct gattttctga ccgtacatgg tctgtggcca
     7261 ggattgccta aatcggttgc tgcccgtggt gttgatgaac gccgctggat gcgcttcggt
     7321 tgcgctactc gcccaatccc gaatctacca gaagcgcacg ccagccggat gtgttcatcg
     7381 ccggaaaccg gattatcact ggaaacggcc gctaaactaa gtgaagtcat gccaggagct
     7441 ggcggacgtt cctgcctgga acgctacgaa tatgccaaac acggtgcctg ctttggtttt
     7501 gatccggacg catacttcgg tacgatggta cgcctgaatc aagaaattaa agagagcgaa
     7561 gccggaaaat tccttgcgga taattacggt aaaacagtga gccgccgtga ctttgacgcc
     7621 gcctttgcca aaagctgggg aaaagagaac gtgaaagcag ttaagctaac gtgccagggt
     7681 aaccctgcgt atttgactga aattcagatc tcgatcaaag ctgacgccat caacgctccg
     7741 ctttctgcaa actcattctt gccacaacca cacccaggca actgtggcaa aacctttgtg
     7801 attgataaag tgggttatta atcatctgat ttacaaaaca cgctaattcg tcttccataa
     7861 accgtgacga ttaagaatta tacataatgc gctgcattga ggaattccct gaatgtgacg
     7921 caaatcactt caaagagtga gcaacagtca gtatcatcat gtgagttaaa ccctcgccgc
     7981 ctgacggtga gggttttctt ttgggtatgt ttatctgcga cactcgcagt accgacgaca
     8041 tggagtaaaa atgtccagac caactatcat cattaacgac ctggatgccg aacgcatcga
     8101 tattctgctg gagcaacccg cctatgctgg tttgccaatc gccgacgcgt taaacgcaga
     8161 gttggatcgc gcccaaatgt gttcgccaga agagatgcca cacgacgtgg tgacaatgaa
     8221 cagccgggtt aaattccgca atcttagcga tggcgaagtg cgtgtgcgca cgctggtgta
     8281 tccggcaaaa atgaccgata gcaatactca gctttccgtt atggctccgg taggtgccgc
     8341 actgctgggg ctgcgcgttg gcgattccat tcactgggaa cttccgggcg gcgttgcaac
     8401 ccaccttgaa gtgctggaac tcgaatacca gccagaagct gctggcgact acctgcttta
     8461 atcccatctg cacaagcgat aactcgcttt gcccagagga tgcactcgca tcctctttac
     8521 gcaaaatcag caatttttcc tggttctcac tgttcacttt tgctgcaaaa ttattccgtt
     8581 tcgtttgtgg gaataaccat ggcagaagca ttttacatcc tgataggatt tctgattatg
     8641 gcggcgatta tcgtcatggc tgtcctttac ctcgaaaacc actcctgacg atcatattgt
     8701 tccccccggc atcgcattca ccagacctga aaccgccttc tgcgccgcct ctgcgctttg
     8761 tgcaccgggt accagaatca ccttacggca ctcctcttca cgtttttcga aaatctcata
     8821 tccccgggcg gcctcttcaa acggcatata gtgggtaaca atttcttctg gtttcagtaa
     8881 tcctttctca attaacggta ataattctcc cagccatgcg tgaacgtggg tctgtcccat
     8941 tttaaacgtc aaccctttat caaaggcgtc gccaaacagg aaaccgtgaa taaatccagc
     9001 gtagacgccc ggtacgctaa caatgccgcc acgcctgacc gccgcaatac actggcgcaa
     9061 cgctttaccg ctgctgccct ccagtttcag gttagtcagc accgtttccg tggtgctgcc
     9121 tttcgcttca aaaccgacgg cgtctattac tgcatccacg ccccggtgac ctgccgtttg
     9181 ttcaataatt gactgtgccg gatcgctatc ttcatcgaaa ttaatcggga tcgcgccgta
     9241 gcggtcagcg gcgaaacgca agcggtaggg atgatgatca acaacaaaaa tctgttccgc
     9301 accgagcaac cgtgcacagg cgattgtcaa caatcccact ggaccggcac catagactgc
     9361 aacgcttgaa ccttgttgga tctgcgcatt ttttgctgcc tgccatgccg ttggcagaat
     9421 atcagaaagg aaaagggctt tatcatctga aagcaaaggc ggtactttaa acggccccac
     9481 attcccttta gggacgcgga catattccgc ctgcccacca ggaacgccgc catacaggtg
     9541 actataacca aacaatgccg cgggagctgg tatctgtttt ttattgagcg cagcgccttt
     9601 acccgcattg gtattttcgc aggcggcata ttgctgcatt cgacagaaaa aacagtcgcc
     9661 acaagcaatg acaaacggaa ttaccacccg gtcgcctttt tgcaaatttt ttacgtcctt
     9721 tccggtttca acgacttccc ccataaattc atgaccaaaa atatcgccat gtttaacctg
     9781 gggtattttg cctcgataaa gatggaggtc agagccacag atcgccgttg ccgtaatacg
     9841 cagaataata tcatcagcct gttcaatgcc cggatcggga acattttcta cctgaacgtg
     9901 atgtgggccg tgataagtca atgctttcat gcaacctcca gagacagttc aaaaaagagt
     9961 cagtctttaa gggtagctat cacagcggga aaacgggcgg taccgcaggt tttgggagaa
    10021 ttcctggtgt tcagtgagaa tatattaatc acagaaaccg ttcgtaagga aaaagaacca
    10081 gacaaatatc agggataaat attataatca tggcgaatga tttgttcatg attaacaggg
    10141 agaaagggtt atgtataaga caatcattat gccagttgat gtatttgaaa tggaattgag
    10201 cgacaaagct gttcgccacg ctgaattcct cgcccaggat gacggagtta ttcatctact
    10261 tcacgtacta cccgggtcag ccagcctgag cctgcaccgt tttgccgctg atgtgcgtcg
    10321 ttttgaagag catctgcaac atgaagcaga agaacgtctg caaacgatgg tcagccactt
    10381 caccatcgat ccttcccgca ttaaacaaca tgtccgtttt ggtagcgtgc gggatgaagt
    10441 caatgagttg gcagaagaac tgggggctga tgttgtagtt attggttctc gcaacccatc
    10501 gatttcgacc catctgttag gttctaacgc ctcgagcgtg atccgccacg ccaatctgcc
    10561 ggtgctggtc gttcgctaac agataaaagt atttatgccg ccctgcctgg aacatcccgg
    10621 cagggctttt taatgccata aaaaagccgc caggtttgac cccggcggct aagcaattgc
    10681 aggtgaatct tacttcttct tatgcagttt tggtgcgaat caggtagtca aaagcactca
    10741 gagaggcttt ggcaccttcg ccagtggcga tgatgatctg cttgtacgga accgtcgtac
    10801 agtcacccgc tgcgaacacg cctttcacgt tggtttcgca tttcgcatca atgataatct
    10861 cgcccatgcg gttacgttcg actgcgcctt ccagccagtt ggtgttcggc agcagaccaa
    10921 tctgcacgaa aataccggcc agttcgatgt tgtgaatatc gccgctgaca cgatctcgat
    10981 attccagacc aacgactttg ctgccgtcgc ctttcacttc cgtggtttgc gcattcagaa
    11041 taatgtcgac gtttttcagg ctgcgcagtt tgtcctgcag aacctggtcg gctttcattt
    11101 ctggcgcaaa ttccagcaga gttacgtgct caacgatacc cgccaggtcg attgccgctt
    11161 ccacgccgga gttaccgccg ccgataaccg ctacgcgttt gcctttaaac agcgggccgt
    11221 cgcagtgcgg gcagtaggtc acgcctttgg tgcgatactg atcttcgccc ggaacgttca
    11281 tgttgcgcca ttttgcaccg gtcgccacga taatgctgcg tgctttcagt accgcgccag
    11341 aagctgtttc aatctggtgt agaccacctt caaccgctgc cgggatcagt ttgctggcgc
    11401 tctggctgtc gatcacatca acgtcgtatt catcaacgtg aactttcagt gcgcctgcca
    11461 gcttctgccc ttcagtcttc ggtacagaaa tgtagttttc gatatcaacg gtatcgagga
    11521 tctgaccacc aaaacgttcg cccatcagac cggtacggat gcctttacgt gcggagtaaa
    11581 ttgctgccgc tgcacccgcc gggccggaac cgacgattaa tacgtcataa gcatcacgct
    11641 tgttcagctc ttctgccgca cgtttttccg cgccagtatc aattttggca acgatttcag
    11701 tcaacgtcat gcggccctga ccaaactctt tcccgtttac gaacactgcc ggaacgccca
    11761 tcacgttgcg atcggtgatt tcgttctgga aggtgccgcc gtcaattgca gtgtgcttga
    11821 tgcgcgggtt cagtacgctc atcaggttca gcgcctgcac cacgtccggg cagttgtggc
    11881 aagagagcga gtaataggtt tcgaattcaa aatcaccgtc aatatggcga atctgctcca
    11941 gcagagactg cgcttctttc gacggatgac caccggtcca cagcaacgcc agtaccagcg
    12001 aggtgaactc gtggcccagc ggggagcctg caaaacgtgg cccctggttg gaacctgggt
    12061 tggtgatcag gaaagacggc ttacgcaccg gcaagctgtt atcttcttta aaggtgactt
    12121 tgtctgacag ttctgcgatt tcagccaaca gttccttgat ttctgccgat ttagcgctgt
    12181 catccagcgt ggcaattaac tcaacaggct tggtcaattt ctcaaggtaa gccttgagtt
    12241 gagttttcat atttgtgtcg agcatgttta tctcctgggc tttaaacatc atcatgcaag
    12301 cggcctctgc ggctacctgg atgcagcttg catcatggtg cggggaagaa aatcgggtgc
    12361 cgcagcaccc gattaattac gcgattgcgg aacttagatt ttaccaacca ggtccagaga
    12421 cggagccaga gttgcttcac cttctttcca tttagccggg caaacttcac ctgggtgaga
    12481 agctacgtac tgtgctgctt tgattttacg cagcaggtca gacgcgtcac ggccaatgcc
    12541 ttcagcggta acttcgattg cctggatgat accctgcggg tcaacaacga aggtcgcacg
    12601 atcagccaga ccttcatctt cacgcatgtt gtcgaagtta cgggtcaggg cgccagtcgg
    12661 gtcgccgatc atcgcatatt tgattttagc gatggtttca gagctgctgt gccatgcttt
    12721 gtgggtgaag tgagtatcgg tagatactgc gtatacgtct acgcccagtt tctgcagttc
    12781 ttcgtagtgg tcagcaacgt cacccagttc ggtcgggcat acgaaagtaa agtcagccgg
    12841 gtagaagaag aagacgctcc agcggccttc ggtatctttt tcggtgattt cgatgaattc
    12901 gccgtttttg aatgcctggt ttttaaaagg tttaattttg gtgttaatca aggacatcta
    12961 tacttcctcc gtgttttcga tgagatgtaa ggtaaccaat ttttgccgat tcggctaatg
    13021 cgtttccatt atcaaatcga taagttttac cttacaacct tcgtaagaca actttgtgaa
    13081 ctttgcaccg ccagcggcga taaaaagtaa aatggccccc tttccaggtg accgtgtaat
    13141 ctgaactacc ctttggtatc ttcagcgcct gcctgcaggc tgaggtgttg cccttacaaa
    13201 tgcaacaacg acatggatta caacaccctc ataaacaaag ggcaatcacc tgatctaagc
    13261 tcttacctat gacagtgata ggttatgcct tttactcgac ttttgcactg actgaaaagg
    13321 acaaattaat gttaaaaaag atacttttac tggctctgct tcctgcaatc gccttcgcag
    13381 aggaacttcc ttccccagta aaagcgattg aaaaacaggg cattacaatc atcaaaacgt
    13441 tcgatgcccc cggaggaatg aaaggttatc tcggaaagta tcaggatatg ggcgtcacca
    13501 tctacctgac tcccgatggt aagcacgcta tctctggtta catgtacaac gagaaaggtg
    13561 aaaacctgag taacacactt atcgaaaaag aaatttacgc accagccgga cgcgaaatgt
    13621 ggcaacggat ggaacaatcc cactggctcc tcgacggtaa aaaagatgcg ccggtcattg
    13681 tctacgtgtt cgccgatccg ttctgcccat attgtaaaca gttctggcag caggcgcgcc
    13741 cgtgggtaga ttctggcaaa gtgcaattaa gaacattgtt ggttggggtt atcaagccag
    13801 aaagcccggc gacagcagcg gcaattcttg cctccaaaga tcccgcaaaa acctggcaag
    13861 aatatgaatc ctctggtggc aagcttaagc taaacgtgcc tgcaaacgta agtacagaac
    13921 aaatgaaagt gttaagcgcc aacgagaaac tcatggacga tctgggggca aatgtcacac
    13981 cagcgatcta ttacatgagt aaggaaaata cgctgcaaca ggccgtgggg ttgcccgatc
    14041 agaaaacgct taatatcatt atggggaata aataaaagat aattcatgga tggttgaaat
    14101 acatccctgc ttttcaacca tcctaaa
//
LOCUS       DAPGUL010000116        14116 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.118, whole genome shotgun sequence.
ACCESSION   DAPGUL010000116 DAPGUL010000000
VERSION     DAPGUL010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14116)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14116)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14116
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.118"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            147..506
                     /locus_tag="RHX21_003714"
     CDS             147..506
                     /locus_tag="RHX21_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001331208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1889 family protein"
                     /protein_id="HDV1988839.1"
                     /translation="MQIKVIYSLIDNMVNFKDKNMPAVIDKALDFIGAMDVSAPTPSS
                     MNESTAKGIFKYLKELGVPASAADITARADQEGWNPGFTEKMVGWAKKMESGERTVIK
                     NPEYFSTYMQEELKALV"
     gene            complement(626..805)
                     /locus_tag="RHX21_003715"
     CDS             complement(626..805)
                     /locus_tag="RHX21_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaH family protein"
                     /protein_id="HDV1988840.1"
                     /translation="MFAGLPSLTHEQQQKAVERIQELMAQGMSSGQAIALVAEELRAN
                     HSGERIVARFEDEDE"
     gene            879..2240
                     /gene="pabB"
                     /locus_tag="RHX21_003716"
     CDS             879..2240
                     /gene="pabB"
                     /locus_tag="RHX21_003716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component 1"
                     /protein_id="HDV1988841.1"
                     /translation="MKTLSPAVITLPWRQDAAEFYFSRLSHLPWAMLLHSGYADHPYS
                     RFDIVVADPICTLTTFGKETVVSESEKRTTTTDDPLQVLQQVLDRADIRPTHNEDLPF
                     QGGALGLFGYDLGRRFESLPEIAEQDIVLPDMAVGIYDWALIVDHQRHTVSLLSHNDV
                     NARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRF
                     HATYSGDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGT
                     LPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPF
                     PAVHHLVSTITARLPEQLHASDLLRAAFPGGSITGAPKVRAMEIIDELEPQRRNAWCG
                     SIGYLSFCGNMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDKVNKILRQ
                     LEK"
     gene            2244..2822
                     /locus_tag="RHX21_003717"
     CDS             2244..2822
                     /locus_tag="RHX21_003717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HDV1988842.1"
                     /translation="MEYRSLTLDDFLSRFQLLRPQINRETLNHRQAAVLIPIVRRPQP
                     GLLLTQRSIHLRKHAGQVAFPGGAVDDTDASVIAAALREAEEEVAIPPSAVEVIGVLP
                     PVDSVTGYQVTPVVGIIPPDLPYRASEDEVSAVFEMPLAQALHLGRYHPLDIYRRGDS
                     HRVWLSWYEQYFVWGMTAGIIRELALQIGVKP"
     gene            3006..4370
                     /gene="sdaA"
                     /locus_tag="RHX21_003718"
     CDS             3006..4370
                     /gene="sdaA"
                     /locus_tag="RHX21_003718"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HDV1988843.1"
                     /translation="MISLFDMFKVGIGPSSSHTVGPMKAGKQFVDDLVEKGLLDSVTR
                     VAVDVYGSLSLTGKGHHTDIAIIMGLAGNEPATVDIDSIPGFIRDVEERERLLLAQGR
                     HEVDFPRDNGMRFHNGNLPLHENGMQIHAYNGDEVVYSKTYYSIGGGFIVDEEHFGQD
                     AANEVSVPYPFKSATELLAYCNETGYSLSGLAMQNELALHSKKEIDEYFAHVWQTMQA
                     CIDRGMNTEGVLPGPLRVPRRASALRRMLVSSDKLSNDPMNVIDWVNMFALAVNEENA
                     AGGRVVTAPTNGACGIVPAVLAYYDHFIESVSPDIYTRYFMAAGAIGALYKMNASISG
                     AEVGCQGEVGVACSMAAAGLAELLGGSPEQVCVAAEIGMEHNLGLTCDPVAGQVQVPC
                     IERNAIASVKAINAARMALRRTSAPRVSLDKVIETMYETGKDMNAKYRETSRGGLAIK
                     VQCD"
     gene            4501..6099
                     /locus_tag="RHX21_003719"
     CDS             4501..6099
                     /locus_tag="RHX21_003719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416329.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDV1988844.1"
                     /translation="MQKAQRIIKTYRRNRMIVCTICALVTLASTLSVRFISQRNLNQQ
                     RVVQFANHAVEELDKVLLPLQAGSEVLLPLIGLPCSVAHLPLRKQAAKLQTVRSIGLV
                     QDGTLYCSSIFGYRNVPVVDILAELPAPQPLLRLTIDRALIKGSPVLIQWTPAAGSSN
                     AGVMEMINIDLLTAMLLEPQLPQISSASLTVDKRHLLYGNGLVDSLPQPEDNENYQVS
                     SQRFPFTINVNGPGATALAWHYLPTQLPLAVLLSLLVGYIAWLATAYRMSFSREINLG
                     LAQHEFELFCQPLLNARSQQCIGVEILLRWNNPRQGWISPDVFIPIAEEHHLIVPLTR
                     YVMAETIRQRHVFPMSSQFHVGINVAPSHFRRGVLIKDLNQYWFSAHPIQQLILEITE
                     RDALLDVDYRIARELHRKNVKLAIDDFGTGNSSFSWLETLRPDVLKIDKSFTAAIGSD
                     AVNSTVTDIIIALGQRLNIELVAEGVETQEQAKYLRRHGVHILQGYLYAQPMPLRDFP
                     KWLAGSQPPPARHNGHITPIMPLR"
     gene            complement(6103..7659)
                     /gene="yoaE"
                     /locus_tag="RHX21_003720"
     CDS             complement(6103..7659)
                     /gene="yoaE"
                     /locus_tag="RHX21_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CNNM family cation transport protein YoaE"
                     /protein_id="HDV1988845.1"
                     /translation="MEFLMDPSIWAGLLTLVVLEIVLGIDNLVFIAILADKLPPKQRD
                     KARLLGLSLALIMRLGLLSLISWMVTLTKPLFTVMDFSFSGRDLIMLFGGIFLLFKAT
                     TELHERLENRDHDSGHGKGYASFWVVVTQIVILDAVFSLDAVITAVGMVNHLPVMMAA
                     VVIAMAVMLLASKPLTRFVNQHPTVVVLCLSFLLMIGLSLVAEGFGFHIPKGYLYAAI
                     GFSIIIEVFNQIARRNFIRHQSTLPLRARTADAILRLMGGKRQANVQHDADNPMPMPI
                     PEGAFAEEERYMINGVLTLASRSLRGIMTPRGEISWVDANLGVDEIREQLLSSPHSLF
                     PVCRGELDEIIGIVRAKELLVALEEGVDVAAIASASPAIIVPETLDPINLLGVLRRAR
                     GSFVIVTNEFGVVQGLVTPLDVLEAIAGEFPDADETPEIITDGDGWLVKGGTDLHALQ
                     QALDVEHLADDDDIATVAGLVISANGHIPRVGDVIDVGPLHITIIEANDYRVDLVRIV
                     KEQPAHDEDE"
     gene            8122..9093
                     /gene="manX"
                     /locus_tag="RHX21_003721"
     CDS             8122..9093
                     /gene="manX"
                     /locus_tag="RHX21_003721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HDV1988846.1"
                     /translation="MTIAIVIGTHGWAAEQLLKTAEMLLGEQENVGWIDFVPGENAET
                     LIEKYNAQLAKLDTTKGVLFLVDTWGGSPFNAASRIVVDKEHYEVIAGVNIPMLVETL
                     MARDDDPSFDELVALAVETGREGVKALKAKPVEKAAPAPAAAAPKAAPTPAKPMGPND
                     YMVIGLARIDDRLIHGQVATRWTKETNVSRIIVVSDEVAADTVRKTLLTQVAPPGVTA
                     HVVDVAKMIRVYNNPKYAGERVMLLFTNPTDVERLVEGGVKITSVNVGGMAFRQGKTQ
                     VNNAVSVDEKDIEAFKKLNARGIELEVRKVSTDPKLKMMDLISKIDK"
     gene            9156..9956
                     /gene="manY"
                     /locus_tag="RHX21_003722"
     CDS             9156..9956
                     /gene="manY"
                     /locus_tag="RHX21_003722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HDV1988847.1"
                     /translation="MEITTLQIVLVFIVACIAGMGSILDEFQFHRPLIACTLVGIVLG
                     DMKTGIIIGGTLEMIALGWMNIGAAVAPDAALASIISTILVIAGHQSIGAGIALAIPL
                     AAAGQVLTIIVRTITVAFQHAADKAADNGNLTAISWIHVSSLFLQAMRVAIPAVIVAL
                     SVGTSEVQNMLNAIPEVVTNGLNIAGGMIVVVGYAMVINMMRAGYLMPFFYLGFVTAA
                     FTNFNLVALGVIGTVMAVLYIQLSPKYNRVAGAPAQAAGNNDLDNELD"
     gene            9969..10820
                     /gene="manZ"
                     /locus_tag="RHX21_003723"
     CDS             9969..10820
                     /gene="manZ"
                     /locus_tag="RHX21_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020804907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IID"
                     /protein_id="HDV1988848.1"
                     /translation="MVDTTQTTTEKKLTQSDIRGVFLRSNLFQGSWNFERMQALGFCF
                     SMVPAIRRLYPENNEARKQAIRRHLEFFNTQPFVAAPILGVTLALEEQRANGAEIDDG
                     AINGIKVGLMGPLAGVGDPIFWGTVRPVFAALGAGIAMSGSLLGPLLFFILFNLVRLA
                     TRYYGVAYGYSKGIDIVKDMGGGFLQKLTEGASILGLFVMGALVNKWTHVNIPLVVSR
                     ITDQTGKEHVTTVQTILDQLMPGLVPLLLTFACMWLLRKKVNPLWIIVGFFVIGIAGY
                     ACGLLGL"
     gene            10875..11333
                     /locus_tag="RHX21_003724"
     CDS             10875..11333
                     /locus_tag="RHX21_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF986 domain-containing protein"
                     /protein_id="HDV1988849.1"
                     /translation="MTITDLVLILFIAALLAFAIYDQFIMPRRNGPTLLAIPLLRRGR
                     IDSVIFVGLIVILIYNNVTNHGALITTWLLSALALMGFYIFWIRVPKIIFKQKGFFFA
                     NVWIEYSRIKAMNLSEDGVLVMQLEQRRLLIRVRNIDDLEKIYKLLVSTQ"
     gene            11762..12328
                     /gene="mntP"
                     /locus_tag="RHX21_003725"
     CDS             11762..12328
                     /gene="mntP"
                     /locus_tag="RHX21_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416335.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese efflux pump MntP"
                     /protein_id="HDV1988850.1"
                     /translation="MNITATVLLAFGMSMDAFAASIGKGATLHKPKFSEALRTGLIFG
                     AVETLTPLIGWGMGMLASRFVLEWNHWIAFVLLIFLGGRMIIEGFRGADDEDEEPRRR
                     HGFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMVGRFIGS
                     IIGKKAEILGGLVLIGIGVQILWTHFHG"
     gene            complement(12325..13134)
                     /gene="rlmA"
                     /locus_tag="RHX21_003726"
     CDS             complement(12325..13134)
                     /gene="rlmA"
                     /locus_tag="RHX21_003726"
                     /EC_number="2.1.1.187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (guanine(745)-N(1))-methyltransferase"
                     /protein_id="HDV1988851.1"
                     /translation="MSFSCPLCHQPLSREKNSYICPQRHQFDMAKEGYVNLLPVQHKR
                     SRDPGDSAEMMQARRAFLDAGHYQPLRDAIVAQLRERLDEKATAVLDIGCGEGYYTHA
                     FADALPEITTFGLDVSKVAIKAAAKRYPQVTLCVASSHRLPFSDTSMDAIIRIYAPCK
                     AEELARVVKPGGWVITATPGPRHLMELKGLIYNEVHLHAPHAEQLEGFTLQQSDELCY
                     PMRLRGDEAVALLQMTPFAWRAKPEVWQTLAAKEVFDCQTDFNIHLWQRSY"
     gene            complement(13300..13509)
                     /gene="cspE"
                     /locus_tag="RHX21_003727"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
     CDS             complement(13300..13509)
                     /gene="cspE"
                     /locus_tag="RHX21_003727"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator/RNA stability
                     regulator CspE"
                     /protein_id="HDV1988852.1"
                     /translation="MAKIKGQVKWFNESKGFGFITPADGSKDVFVHFSAIQGNGFKTL
                     AEGQNVEFEIQDGQKGPAAVNVTAI"
     gene            complement(13522..13665)
                     /locus_tag="RHX21_003728"
     CDS             complement(13522..13665)
                     /locus_tag="RHX21_003728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YobF family protein"
                     /protein_id="HDV1988853.1"
                     /translation="MCGIFSKEVLSKHVDVEYRFSAEPYIGASCSNVSVLSMLCLRAK
                     KTI"
BASE COUNT         3525 a         3506 c         3492 g         3593 t
ORIGIN      
        1 tagctgaata atctggttat agcgtgagga ctgaccgtta aatttctcca tcttactgga
       61 taacacacca tgagctgcta cctttaaaac acctgaatgt caacaggtta actcgtgcca
      121 tatcgttata atccctttga tattagatgc aaattaaggt catatatagt cttatcgata
      181 acatggttaa ttttaaggat aagaatatgc ctgctgtaat agataaagcc ctggatttca
      241 ttggtgccat ggatgtatca gcgccaacac caagttcgat gaatgaaagc acagcgaagg
      301 gaatctttaa atatttaaaa gaactgggag tacccgcgag tgccgctgat attacggcgc
      361 gagctgacca ggaaggctgg aaccctgggt tcacggaaaa aatggttgga tgggcaaaaa
      421 aaatggagtc tggtgaacgc actgtaatta aaaatcctga atacttttca acatatatgc
      481 aggaagaact aaaagcactg gtctgagctt aatttatatc agcataaatg ggtcaggacg
      541 cttttaatca catataaaaa gcgtcctttt tctcacaatc aaataatcat cggattctat
      601 aacgaaatcg atacggatta gtgtgttact cgtcttcatc ctcaaaacgc gccacgattc
      661 gctcgccgga gtggttggca cgcagctctt ctgccaccag cgcgattgcc tggccgctgc
      721 tcatcccttg tgccatcagt tcctggatcc gctcgacagc tttttgctgc tgttcatggg
      781 tgagtgaagg taaacctgca aacattgtta actcctgcta aattgttggc gctaattatt
      841 tcatgctacc cggcacatag ccagtagagt caggactgat gaagacgtta tctcccgctg
      901 tgattacttt accctggcgt caggacgccg ctgaatttta tttctcccgc ttaagccacc
      961 tgccgtgggc gatgctttta cactccggct atgccgatca tccgtatagc cgctttgata
     1021 ttgtggtcgc cgatccgatt tgcactttaa ccactttcgg taaagaaacc gttgttagtg
     1081 aaagcgaaaa acgcacaacg accactgatg acccgctaca ggtgctccag caggtgctgg
     1141 atcgcgcaga cattcgccca acgcataacg aagatttgcc atttcagggc ggcgcactgg
     1201 ggttgtttgg ctacgatctg ggccgccgtt ttgagtcact gccagaaatt gcggaacaag
     1261 atatcgttct gccggatatg gcagtgggta tctacgattg ggcgctcatt gtcgaccacc
     1321 agcgtcatac agtttctttg ctgagtcata atgatgtcaa tgcccgtcgg gcctggctgg
     1381 aaagccagca attctcgccg caggaagatt tcacgctcac ttccgactgg caatccaata
     1441 tgacccgcga gcagtacggc gaaaaatttc gccaggtaca ggaatatctg cacagcggtg
     1501 attgctatca ggtgaatctc gcccagcgtt ttcatgcgac ctattctggc gatgaatggc
     1561 aggcattcct tcagcttaat caggccaacc gcgcgccatt tagcgctttt ttacgtcttg
     1621 aacagggtgc aattttaagc ctttcgccag agcgatttat tctttgtgat aatagtgaaa
     1681 tccagacccg cccgattaaa ggcacgctac cacgcctgcc cgatcctcag gaagatagca
     1741 aacaagcaga aaaactggcg aactcagcga aagatcgtgc cgaaaatctg atgattgtcg
     1801 atttaatgcg taatgatatc ggtcgtgttg ccgtagccgg ttcggtaaaa gtaccagagc
     1861 tgttcgtggt ggaacccttc cctgccgtgc atcatctggt cagcactata acggcgcgac
     1921 taccagaaca gttacacgcc agcgatctgc tgcgcgcagc ttttcctggt ggctcaataa
     1981 ccggggctcc gaaagtacgg gctatggaaa ttatcgacga actggaaccg cagcgacgta
     2041 atgcctggtg cggcagcatt ggctatttga gcttttgcgg caacatggat accagcatta
     2101 ctatccgcac gctgactgcc attaacggac aaatatactg ctctgcgggc ggtggaattg
     2161 tcgccgatag ccaggaagaa gcggaatatc aggaaacttt tgataaagtt aataagatat
     2221 tacgccaact ggagaagtaa gacgtggaat accgtagcct gacgcttgat gattttttat
     2281 ctcgctttca acttttgcgc ccgcaaatta accgggaaac cctaaatcat cgtcaggctg
     2341 ccgtgttaat ccccatcgtc cgtcgaccgc aaccggggtt gttgctgact cagcgttcaa
     2401 ttcatctgcg taaacacgct ggacaagtgg cattccctgg aggtgcagtc gatgacacgg
     2461 acgcatcagt tatcgccgcc gcgctgcgcg aagctgaaga agaggtcgct ataccgcctt
     2521 ccgccgttga agttatcggc gtgctgccgc ccgtcgatag cgtaactggc tatcaggtaa
     2581 ccccagtggt cggcattatc ccgcccgatc tgccgtatcg cgccagtgaa gatgaagtct
     2641 cggcggtgtt tgaaatgccg ctcgcccagg cattacatct gggtcgttat caccctttag
     2701 atatctaccg ccgtggcgat tcacatcggg tatggctgtc ctggtacgaa cagtattttg
     2761 tatggggaat gaccgcaggc ataattcgtg agctggcgct gcaaattggt gtgaaaccct
     2821 gactatactt atctttacat ctacaaaaca ctacttgaga caatcatcgc aatattagtt
     2881 aaatcgcggt ttttgattag tttaattcat gtgaatagtt aagccagtcg ccgcgttccc
     2941 tcttacacta tgcgctgtta ttagttcgtt actggaagtc cagtcacctt gtcaggagta
     3001 ttatcgtgat tagtctattc gacatgttta aggtggggat tggtccctca tcttcccata
     3061 ccgtagggcc tatgaaggcg ggtaaacagt tcgtcgatga tctggtcgaa aaaggcttac
     3121 tggatagcgt tactcgcgtt gccgtggacg tttatggttc actgtcgctg acgggtaaag
     3181 gccaccacac cgatatcgcc attatcatgg gtcttgcagg taacgaacct gccaccgtgg
     3241 atatcgacag tattcccggt tttattcgcg acgtagaaga gcgcgaacgt ctgctgctgg
     3301 cacagggacg gcatgaagtg gatttcccgc gcgacaacgg gatgcgtttt cataacggca
     3361 acctgccgct gcatgaaaac ggtatgcaaa tccacgccta taacggcgat gaagtcgtct
     3421 acagcaaaac ttattattcc atcggcggcg gttttatcgt cgatgaagaa cactttggtc
     3481 aggatgctgc caacgaagtg agcgtgccgt atccgttcaa atctgccacc gaactgctcg
     3541 cgtactgtaa tgaaaccggc tattcgctgt ctggtctcgc tatgcagaac gaactggcgc
     3601 tgcacagcaa gaaagagatc gacgagtatt tcgcgcatgt ctggcaaacc atgcaggcat
     3661 gtatcgatcg cgggatgaac accgaaggtg tactgccagg cccgctgcgc gtgccacgtc
     3721 gtgcgtctgc cctgcgccgg atgttagttt ccagcgataa actgtctaac gatccgatga
     3781 atgtcattga ctgggtaaac atgtttgcgc tggcagttaa cgaagaaaac gccgccggtg
     3841 gtcgtgtggt aactgcgcca accaacggtg cctgcggtat cgttccggca gtgctggctt
     3901 actatgacca ctttattgaa tcggtcagcc cggacatcta tacccgttac tttatggcag
     3961 cgggcgcgat tggtgcattg tataaaatga acgcctctat ttccggtgcg gaagttggtt
     4021 gccagggcga agtgggtgtt gcctgttcaa tggctgctgc gggtcttgca gaactgctgg
     4081 gcggtagccc ggaacaggtt tgcgtggcgg cggaaattgg catggaacac aaccttggtt
     4141 taacctgcga cccggttgca gggcaggttc aggtgccgtg cattgagcgt aatgccattg
     4201 cctctgtgaa ggcgattaac gccgcacgga tggctctgcg ccgcaccagt gcaccgcgcg
     4261 tctcgctgga taaggtcatc gaaacgatgt acgaaaccgg taaggacatg aacgccaaat
     4321 accgcgaaac ctcacgcggt ggtctggcaa tcaaagtcca gtgtgactaa tacttcttac
     4381 tcgcccatct gcaacggatg ggcgaattta tacccgcttt ctcgtctgct gtaatattcc
     4441 ccactacact tccactgttg cgtcaggcgt ttgtcgccat acgcttacag ggtggcccgc
     4501 atgcaaaaag cacaacggat cattaaaacc tatcgccgta atcgaatgat tgtttgtacg
     4561 atttgcgcac tcgttacgct cgcttcgacc ctgagcgtgc gatttatttc acagcgtaac
     4621 ttaaatcaac aacgggtagt acaattcgcc aatcacgctg tagaggaatt agataaagta
     4681 ctgcttcccc tacaggcagg tagcgaagtc ttgcttccgc tgattggtct gccctgctct
     4741 gtcgcccatt tgccattacg taaacaggcg gcaaaactcc aaactgtgcg atccattggc
     4801 ctggtgcaag acggcacact ctattgctcc agcatttttg gttatcgcaa tgtgcccgtc
     4861 gtggacattc tggctgaact tcctgcaccg caaccacttt tacgcctgac gatcgaccgt
     4921 gccctgatta aaggcagtcc ggttttgatt caatggacgc ctgcagcggg cagtagcaat
     4981 gctggggtca tggagatgat taacatcgac ttactgacgg caatgctcct tgagccacaa
     5041 ctgccgcaaa tcagtagcgc cagcctgacg gtggacaaac ggcatttgct ctatggtaat
     5101 gggctggtag attcccttcc gcaacctgaa gacaatgaaa actatcaggt ttcttcgcaa
     5161 cgctttcctt ttaccattaa cgttaatggt ccgggggcta cggcgctggc atggcactat
     5221 cttccaacac aattaccgct ggcggtgctg ctaagtttac tggtgggcta catcgcctgg
     5281 ctggcgaccg cttaccggat gagcttttcc cgcgaaatca atctgggcct ggcgcaacat
     5341 gagttcgaat tgttctgtca gcctttgctt aatgcgcgca gccagcaatg tattggtgta
     5401 gagattttgc tgcgctggaa caatccgcgt cagggctgga tttcaccgga tgtgtttatt
     5461 cctatcgcgg aagaacatca tttaattgtg ccactgaccc gctatgtgat ggcagaaacc
     5521 attcgtcagc gccatgtttt cccgatgagt agtcagtttc atgttggcat taacgtcgca
     5581 cccagccatt ttcgccgtgg tgtgctgata aaagatctca atcagtactg gtttagcgct
     5641 cacccgattc agcaactgat cctcgaaatc accgaacgcg atgccttact ggatgttgat
     5701 tatcggattg cccgcgagct acatcgtaaa aacgtcaaac tggcgattga tgacttcggc
     5761 accggcaaca gttcattttc ctggcttgaa acattacgtc ctgacgtgct gaaaattgat
     5821 aagtcattta ccgcagctat aggttctgac gcggttaact cgacggtgac cgatatcatc
     5881 atcgcgctgg ggcaaagact gaatattgaa ctggtggcgg agggcgtgga aacgcaagaa
     5941 caggcgaagt atttgcgccg tcatggcgtg catattttgc aagggtattt gtacgcacag
     6001 ccgatgccgc tacgtgattt tcccaaatgg ctggcgggca gccaaccgcc gcccgcccgg
     6061 cataatggac atatcacgcc cattatgccg ttacgttaat gcttactcat cttcatcgtg
     6121 cgccggttgc tctttaacaa tgcgaaccag atcaacacga taatcattgg cttcaatgat
     6181 ggtgatatgc agtggcccta catcaatcac atcgcccaca cggggaatgt gaccatttgc
     6241 cgagatcacg aggcccgcga ccgtcgcgat atcatcgtca tcggcaaggt gctcaacatc
     6301 aagcgcctgc tgcaaggcat gcaaatctgt accgcctttt accagccagc cgtcaccatc
     6361 agtaatgatt tccggcgttt cgtcagcgtc cgggaattca cccgcaatgg cttccagcac
     6421 atccagcggc gtgaccagac cttgtaccac accaaactcg ttggtcacga taacaaagct
     6481 cccgcgagca cgacgcagca cgcccaacag gttgatcgga tcgagggttt ccgggacgat
     6541 aatcgccgga gacgccgaag caatcgccgc cacatcaacg ccctcttcca gcgccaccag
     6601 cagttcttta gcacgtacaa taccgatgat ttcatccagt tcaccgcgac ataccgggaa
     6661 cagactgtgc ggtgaagaga gcagttgctc gcggatttca tcgaccccga gattagcgtc
     6721 aacccagctt atttcaccgc gcggcgtcat gatcccgcgc agagaacgcg acgccagcgt
     6781 cagtacgccg ttaatcatgt aacgttcttc ttcggcaaat gcaccttccg ggatcggcat
     6841 cggcatcggg ttatcggcat cgtgctgaac attggcctga cgtttcccgc ccatcaaacg
     6901 caggatggca tcggcagtac gcgctcgcag cggcaaagtc gactggtggc gaataaagtt
     6961 gcgacgcgca atctggttaa acacttcgat gatgatcgag aagccaatcg cggcatacag
     7021 gtaacctttc ggaatgtgga aaccgaaacc ttctgccacc agactcagac caatcattaa
     7081 caggaagctc agacagagca ccaccaccgt ggggtgctgg ttaacgaatc gcgtcagcgg
     7141 tttggatgcc agcaacataa ccgccatcgc aatcactacc gccgccatca tcaccggcag
     7201 atggttaacc atccctactg cagtaattac cgcatccaac gagaagacgg cgtcaaggat
     7261 gacaatctgt gtgacgacca cccagaaact ggcgtagcct ttaccgtggc cggaatcatg
     7321 atcgcggttt tccagccgtt catgcagttc ggttgttgct ttgaacagca agaatatccc
     7381 cccgaacaac ataatcaggt cgcgtccgga gaaggagaaa tccatgacgg taaatagcgg
     7441 tttggtcagc gtgaccatcc atgaaatcag cgacagcagc cccagacgca taatcagcgc
     7501 cagtgataac cccagcaaac gcgctttatc gcgttgtttt ggcggcagtt tgtcagcaag
     7561 aatggcgatg aagaccaggt tatcgatacc cagcacaatt tcgagaacaa caagcgtgag
     7621 tagccccgcc caaattgagg ggtccattaa gaattccatg acaagctcct gcttaaggaa
     7681 tagctattcg acgccagaaa taatgcaggc gtaacgacaa aatgcaaacg aaaggtgcgg
     7741 catagagagc cagaaaggta ggcgttaaaa ggcctgatgc tgaaatgacg tcggtgacga
     7801 tccatactgc gggctactgc cctatactcc atggttgtta aacgggagtt aaacatatca
     7861 gagacgcctc tgatttggca aagatttacc ttcctttgca aacgaatgtg acaaggatat
     7921 tttacctttc gaaatttctg ctaatcgaaa gttaaattac ggatcttcat cacataaaat
     7981 aattttttcg atatctaaaa taaatcgcga aacgcagggg tttttggttg tagcccttat
     8041 ctgaatcgat tcgattgtgg acgacgattc aaaaatacat ctggcacgtt gaggtgttaa
     8101 cgataataaa ggaggtagca agtgaccatt gctattgtta taggcacaca tggttgggct
     8161 gcagagcagt tgcttaaaac ggcagaaatg ctgttaggcg agcaggaaaa cgtcggctgg
     8221 atcgatttcg ttccaggtga aaatgccgaa acgctgattg aaaagtacaa cgctcagttg
     8281 gcaaaactcg acaccactaa aggcgtgctg tttctcgttg atacatgggg aggcagcccg
     8341 ttcaatgctg ccagccgcat tgtcgtcgac aaagagcatt atgaagtcat tgcaggcgtt
     8401 aacattccaa tgctcgtgga aacgttaatg gcccgtgatg atgacccaag ctttgatgaa
     8461 ctggtggcac tggcagtaga aacaggccgt gaaggcgtga aagctctgaa agccaaaccg
     8521 gttgaaaaag ccgcgccagc acccgctgcc gcagcaccaa aagcggctcc aactccggca
     8581 aaaccaatgg ggccaaacga ctacatggtt attggccttg cgcgtatcga cgaccgtctg
     8641 attcacggtc aggtcgccac ccgctggacc aaagaaacca atgtctcccg tattattgtt
     8701 gttagtgatg aagtggctgc ggataccgtt cgtaagacac tgctcaccca ggttgcacct
     8761 ccgggcgtaa cagcacacgt agttgatgtt gccaaaatga ttcgcgtcta caacaacccg
     8821 aaatatgctg gcgaacgcgt aatgctgtta tttaccaacc caacagatgt agagcgtctc
     8881 gttgaaggcg gcgtgaaaat cacctctgtt aacgtcggtg gtatggcatt ccgtcagggt
     8941 aaaacccagg tgaataacgc ggtttcggtt gatgaaaaag atatcgaggc gttcaagaaa
     9001 ctgaatgcgc gcggtattga gctggaagtc cgtaaggttt ccaccgatcc gaaactgaaa
     9061 atgatggatc tgatcagcaa aatcgataag taacgtattg tgttgattat cactcagttt
     9121 tcacacttaa gtcttacgta aacaggagaa gtacaatgga gattaccact cttcaaattg
     9181 tgctggtatt tatcgtagcc tgtatcgcag gtatgggatc aatcctcgat gaatttcagt
     9241 ttcaccgtcc gctaatcgcg tgtaccctgg tgggtatcgt tcttggggat atgaaaaccg
     9301 gtattattat cggtggtacg ctggaaatga tcgcgctggg ctggatgaac atcggtgctg
     9361 cagttgcgcc tgacgccgct ctggcttcta tcatttctac cattctggtt atcgcaggtc
     9421 atcagagcat tggtgcaggt atcgcactgg caatccctct ggccgctgcg ggccaggtac
     9481 tgaccatcat cgttcgtact attaccgttg ctttccagca cgctgcggat aaggctgctg
     9541 ataacggcaa cctgacagcg atttcctgga tccacgtttc ttctctgttc ctgcaagcaa
     9601 tgcgtgtggc tattccggcc gtcatcgttg cgctgtctgt tggtaccagc gaagtacaga
     9661 acatgctgaa tgcgattccg gaagtggtga ccaatggtct gaatatcgcc ggtggcatga
     9721 tcgtggtggt tggttatgcg atggttatca acatgatgcg tgctggctac ctgatgccgt
     9781 tcttctacct cggcttcgta accgcagcat tcaccaactt taacctggtt gctctgggtg
     9841 tgattggtac tgttatggca gtgctctaca tccaacttag cccgaaatac aaccgcgtag
     9901 ccggtgcgcc tgctcaggca gctggtaaca acgatctcga taacgaactg gactaacagg
     9961 tgagcgaaat ggttgataca actcaaacta ccaccgagaa aaaactcact caaagtgata
    10021 ttcgtggcgt cttcctgcgt tctaacctct tccagggttc atggaacttc gaacgtatgc
    10081 aggcactggg tttctgcttc tctatggtac cggcaattcg tcgcctctac cctgagaaca
    10141 acgaagctcg taaacaagct attcgccgtc acctggagtt ctttaacacc cagccgttcg
    10201 tggctgcgcc gattctcggc gtaaccctgg cgctggaaga acagcgtgct aatggcgcag
    10261 agatcgacga cggtgctatc aacggtatca aagtcggttt gatggggccg ctggctggtg
    10321 taggcgaccc gatcttctgg ggaaccgtac gtccggtatt tgcagcactg ggtgccggta
    10381 tcgcgatgag cggcagcctg ttaggtccgc tgctgttctt catcctgttt aacctggtgc
    10441 gtctggcaac ccgttactac ggcgtagcgt atggttactc caaaggtatc gatatcgtta
    10501 aagatatggg tggtggcttc ctgcaaaaac tgacggaagg ggcgtctatc ctcggcctgt
    10561 ttgtcatggg ggcattggtt aacaagtgga cacatgtcaa catcccgctg gttgtctctc
    10621 gcattactga ccagacgggc aaagaacacg ttactactgt ccagactatt ctggaccagt
    10681 taatgccagg cctggtacca ctgctgctga cctttgcttg tatgtggcta ctgcgcaaaa
    10741 aagttaaccc gctgtggatc atcgttggct tcttcgtcat cggtatcgct ggttacgctt
    10801 gcggcctgct gggactgtaa gactgttgta cactaccggg gccttttggc cccgtttttt
    10861 tatctggagg attaatgaca atcacggacc tggtactgat tcttttcatc gccgcactcc
    10921 tggccttcgc gatctacgat cagttcatca tgccccgccg taacggcccc accctgctgg
    10981 caattccttt gctccggcgt ggtcgcatcg atagcgttat cttcgtcgga ttgattgtca
    11041 ttcttatcta taacaacgtc acgaatcatg gcgcgctaat aacaacatgg ttattaagtg
    11101 cactggctct gatgggtttt tatatattct ggatccgcgt tccgaagatc atctttaaac
    11161 aaaaaggttt tttcttcgcc aatgtctgga ttgaatatag ccgaatcaaa gcgatgaact
    11221 tgtcggaaga tggcgtgttg gtgatgcaat tagaacagcg tcggctgtta atccgcgttc
    11281 gaaatatcga cgatctggaa aaaatttata agcttctcgt atcaactcaa taacttatga
    11341 atttagccaa agctatgttt agtgtatttt taataatcag acatagctta ggctatatta
    11401 tctcttccct tatttgttat ttattttaac gtttcattga tatataaatc taaataaaaa
    11461 tcgttatcaa taaagcaatg aaataatata ttccaacagt tgttttatat tctcaaaata
    11521 tgttaaggtt gcgccctcat ttggggagta gctgatttcc agattccgga aatgtacgtg
    11581 tcaacatact cgttgcaaaa cgtggcacgt acggactgaa gactttcagt caggcgagac
    11641 catatgcaca tcaatcgcta tgcctgcatg aacgcgaaaa ccatcgcggc ttgttgttca
    11701 tgtatgcatg tttgctgggg gcgatgatgt gttttatgga taccccggtc aggacgttgt
    11761 catgaatatc actgctactg ttcttcttgc gtttggtatg tcgatggatg catttgctgc
    11821 atcaatcggt aaaggtgcca ccctccataa accgaaattt tctgaagcat tgcgaaccgg
    11881 ccttattttt ggtgccgtcg aaaccctgac gccgctgatc ggctggggaa tgggcatgtt
    11941 agccagccgg tttgtccttg aatggaatca ctggattgcg tttgtgctgc tgatattcct
    12001 cggcgggcga atgattattg agggttttcg tggcgcagat gatgaagatg aagagccgcg
    12061 ccgtcggcac ggtttctggc tactggtaac caccgcgatt gccaccagcc tggatgccat
    12121 ggctgtgggt gttggtcttg ctttcctgca ggtcaacatt atcgcgaccg cattggccat
    12181 tggttgtgca accttgatta tgtcgacatt agggatgatg gttggtcgct ttatcggctc
    12241 aattattggg aaaaaagcgg aaattctcgg cgggctggta ctgatcggca tcggcgtcca
    12301 gatcctctgg acgcacttcc acggttaata agaacgctgc cagaggtgaa tattaaagtc
    12361 cgtctggcag tcgaacactt cttttgctgc cagtgtttgc cagacttctg gcttcgcacg
    12421 ccaggcaaac ggcgtcatct gcaataatgc gacggcttca tcaccgcgaa gacgcatcgg
    12481 ataacacaac tcatcactct gctgtaatgt aaaaccttcc agttgttctg catgaggtgc
    12541 atgaagatgt acttcattgt aaatcagccc cttcagctcc atcaaatgtc gcggtcccgg
    12601 cgtggcagta atgacccagc cgccgggctt cactactcgt gctaattctt ctgctttaca
    12661 cggcgcgtaa atacgtatta tggcgtccat actggtatcg gaaaacggca aacggtggct
    12721 ggaagcgaca caaagagtga cctgcggata gcgtttcgcc gccgctttta tcgctacctt
    12781 cgagacatcc aggccaaacg tggtgatttc gggcaacgca tcggcaaatg cgtgtgtgta
    12841 atacccttca ccacagccaa tatccagcac tgccgtggcc ttttcatcaa gccgttcccg
    12901 cagttgggcg acaattgcat cacgcagcgg ctgataatgt ccggcatcta agaatgcgcg
    12961 gcgtgcttgc atcatttccg cgctgtcgcc cggatcacga gaccgtttat gctgaacggg
    13021 cagcagattg acataccctt ctttcgccat atcaaactga tgtcgctggg gacagatata
    13081 gctgtttttt tcacgcgaaa gaggctgatg gcaaagtgga caggaaaacg acatgacaac
    13141 tccggcagga tactaaaggc cgcaagtgta acgcgaatca cgcggcgggc aaatatccga
    13201 acgccaggag cgaagataaa gcatagtaaa aagcctcgca ttcgacgagg ctttatagcg
    13261 agattgaagc gtattcacac ttcagatcag tggattcgat cagatagctg ttacgttaac
    13321 agctgccgga cctttctggc cgtcctgaat ttcgaactca acgttctgac cttcagccag
    13381 agttttgaag ccattaccct ggatagcgga gaagtgtacg aacacgtctt tgctgccatc
    13441 agccggagta atgaagccaa aacctttaga ctcgttgaac cacttaacct gacctttaat
    13501 ctttgccatt tgaaaaattc cttagattgt tttcttcgcc cgcaggcata acatagataa
    13561 aactgacaca ttactgcatg aggcaccaat ataaggctcg gcagagaagc ggtattcaac
    13621 gtcaacgtgt ttactcagga cttctttact gaaaatgcca cacataaaca gaactgtacc
    13681 tcgtttaacc cgaaatctgt tatcacatac aacgttaatt atggcaagcc atttttaaac
    13741 atgtctcgat cagacgcaca aatctcgata cgtcttccac tttttttgca cacttatgca
    13801 acggaatacg cgccgatata tcattgtgct taaccttgcc agttcaggca gatacttaaa
    13861 ctggcgtagt ttctaacata gttcaataag ttcagttgtt ccaggccagt gggagaagtt
    13921 attacatagt gcgtgcaata tcacattttc tgctatgcaa tgaataaaaa gttatatcac
    13981 tttttctcat aaaacagtca gttaacggct atcaattacc ctaaagagaa gtcaatcccc
    14041 aaagggattg taaatttaaa ataagaaaaa ttgatgagtg agcaaaaaaa tcaagagaga
    14101 aacgtttcgc taataa
//
LOCUS       DAPGUL010000117        13914 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.119, whole genome shotgun sequence.
ACCESSION   DAPGUL010000117 DAPGUL010000000
VERSION     DAPGUL010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13914
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.119"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            53..847
                     /gene="hyxR"
                     /locus_tag="RHX21_003729"
     CDS             53..847
                     /gene="hyxR"
                     /locus_tag="RHX21_003729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001304859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LuxR family transcriptional regulator HyxR"
                     /protein_id="HDV1988854.1"
                     /translation="MKKPLVIISACQFTRLALESLIPADRYIVRVYSNVTTEVEFVLK
                     TSCGYLLADIPSLPSGELVLLACLVRLRSDAGQWQVCLTGDSDWFDNAPASSLYNGFP
                     HIGTLLKASRYQNQIIRWLLRPLPGDMSDFWLLTARELSVLKILMQGMSFSEIARYEQ
                     RSSKTLHAIATQALRKLGLGTLSDFRLLYTGCGDSRVKRNIRLHARYVGQHSAHRLTQ
                     YVQNMVSGILYPEKVIVGKSINSDAISGKVLSGQRKHMSKKRPGVL"
     gene            1001..1762
                     /gene="hyxA"
                     /locus_tag="RHX21_003730"
     CDS             1001..1762
                     /gene="hyxA"
                     /locus_tag="RHX21_003730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein HyxA"
                     /protein_id="HDV1988855.1"
                     /translation="MRFVLFCPSGIVPAQFEALSTGSVCNITCIRTEEELRNKLRHRP
                     QSVVISAGRPAECAEMWFRFYRDHSFVVVLCVAPFFLPPDVSISGVLKNLRLLKTGMS
                     VERAISVANASGGFSGLKHAENLPVMDSYSVFMNEVNNRTKTIVMSERFPEKQKKVLS
                     LLLAGHSWEYSAQFLKTGIRQIWLAEQSLKKRWGIPDSMSLREALLLSSNKFHGDGNA
                     LEKTNAMTLRENGNTNRYSVVVNAGTQALSLHKYK"
     gene            1804..2886
                     /locus_tag="RHX21_003731"
                     /pseudo
     CDS             1804..2886
                     /locus_tag="RHX21_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308377.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
     gene            2908..4101
                     /locus_tag="RHX21_003732"
     CDS             2908..4101
                     /locus_tag="RHX21_003732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308376.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HDV1988856.1"
                     /translation="MTKATVNTGTFASQNGTLIVDASSENTLDISGKASGDLRVYSAG
                     SLDLINEQTAFISTGKDSTLKATGTTEGGLYQYDLTQGADGNFYFVKNTHKASNASSL
                     IQAMAAAPANVANLQADTLSARQDAVRLSENDKGGVWIQYFGGKQKHTTAGNASYDLD
                     VNGVMLGGDTRFMTEDGSWLAGVAMSSAKGDMTTMQSKGDTEGYSFHAYLSRQYNNGI
                     FIDTAAQFGHYSNTADVRLMNGGGTIKADFNTNGFGAMVKGGYTWKDGNGLFIQPYAK
                     LSALTLEGVDYQLNGVDVHSDSYNSVLGEAGTRVGYDFAVGNSTVKPYLNLAALNEFS
                     DGNKVRLGDESVNASIDGAAFRVGAGVQADITKNMGAYASLDYTKGDDIENPLQGVVG
                     INVTW"
     gene            4285..4950
                     /locus_tag="RHX21_003733"
     CDS             4285..4950
                     /locus_tag="RHX21_003733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988857.1"
                     /translation="MREQIKQDIDLIEILFYLKKKIRVILFIIAICMAMVLLFLYINK
                     DNIKVSYSLKINQTTPGILVNCDSNNNFACQTTMTEDVIQRITTFFHTSPDVKNREIK
                     LEWSGDKRDLPTAEAEISRVQASIIKWYASEYHNGRQVLDEIQTPSAINSELYTKMIY
                     LTRNWSLYPNGDGCVTISSPEIKNKYPAAICLALGFFLSIVISVMFCLVKKMVDEYQQ
                     NSG"
     gene            complement(5196..5891)
                     /locus_tag="RHX21_003734"
     CDS             complement(5196..5891)
                     /locus_tag="RHX21_003734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414842.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein C"
                     /protein_id="HDV1988858.1"
                     /translation="MDNRSEFLNNVAQALGRPLRLEPQAEDAPLNNYANERLTALNQQ
                     QRCDAFIQFASDVMLTRCELTSEAKAAEAAIRLCKELGDQSVVISGDTRLEELGISER
                     LQQECNAVVWDPAKGAENISQAEQAKVGVVYAEYGLTESGGVVLFSAAGRGRSLSLLP
                     ESSLFILRKSTILPRVAQLAEKLHQKAQAGERMPSCINIISGPSSTADIELIKVVGVH
                     GPVKAVYLIIEDC"
     gene            complement(5884..7311)
                     /locus_tag="RHX21_003735"
     CDS             complement(5884..7311)
                     /locus_tag="RHX21_003735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster-binding protein"
                     /protein_id="HDV1988859.1"
                     /translation="MSIKTSNTDFKTRIRQQIEDPIMRKAVANAQQRIGANRQKMVDE
                     LGHWEEWRDRAAQIRDHVLSNLDAYLYQLSEKVTQNGGHVYFAKTKEDATRYILQVAQ
                     RKNARKVVKSKSMVTEEIGVNHVLQDAGIQVIETDLGEYILQLDQDPPSHVVVPAIHK
                     DRHQIRRVLHELLGYEGPETPEAMTLFIRQKIREDFLSAEIGITGCNFAVAETGSVCL
                     VTNEGNARMCTTLPKTHIAVMGMERIAPTFAEVDVLITMLARSAVGARLTGYNTWLTG
                     PREAGHVDGPEEFHLVIVDNGRSEVLASEFRDVLRCIRCGACMNTCPAYRHIGGHGYG
                     SIYPGPIGAVISPLLGGYKDFKDLPYACSLCTACDSVCPVRIPLSKLILRHRRVMAEK
                     GITAKAEQRAIKMFAYANSHPGLWKVGMMAGAHAASWFINGGKTPLKFGAISDWMEAR
                     DLPEADGESFRSWFKKHLAQEKKNG"
     gene            complement(7322..8041)
                     /locus_tag="RHX21_003736"
     CDS             complement(7322..8041)
                     /locus_tag="RHX21_003736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(Fe-S)-binding protein"
                     /protein_id="HDV1988860.1"
                     /translation="MNVNFFVTCIGDALKSRMARDSVLLLEKLGCRVNFPEKQGCCGQ
                     PAINSGYIKEAIPGMKNLIAALEDNDDPIISPAGSCTYAVKSYPMYLADEPEWASRAE
                     KVAARMQDLTSFIVNKLGVVDVGASLQGRAVYHPSCSLARKLGVKDEPLTLLKNVRGL
                     ELLTFAEQDTCCGFGGTFSVKMAEISGEMVKEKVVHLMEVRPEYLIGADVSCLLNISG
                     RLQREGQKVKVMHIAEVLMSR"
     gene            complement(8570..9424)
                     /gene="rclR"
                     /locus_tag="RHX21_003737"
     CDS             complement(8570..9424)
                     /gene="rclR"
                     /locus_tag="RHX21_003737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator RclR"
                     /protein_id="HDV1988861.1"
                     /translation="MDALSRLLMLNAPQGTIDKNCVLGSDWQLPHGAGELSVIRWHAL
                     TQGAAKLEMPTGEIFTLRPGNVVLLPQNSAHRLSHVDNESTCIVCGTLRLQHSARYFL
                     TSLPETLFLAPVNHSVEYNWLREAIPFLQQESRSAMPGVDALCSQICATFFTLAVREW
                     IAQVNTEKNILSLLLHPRLGAVIQQMLEMPGHAWTVESLASIAHMSRASFAQLFRDVS
                     GTTPLAVLTKLRLQIAAQMFSREMLPVVVIAESVGYASESSFHKAFVREFGCTPGEYR
                     ERVRQLAP"
     gene            9650..10975
                     /locus_tag="RHX21_003738"
     CDS             9650..10975
                     /locus_tag="RHX21_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414838.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridine nucleotide-disulfide oxidoreductase"
                     /protein_id="HDV1988862.1"
                     /translation="MNKYQAVIIGFGKAGKTLAVTLAKAGWRVALIEQSNAMYGGTCI
                     NIGCIPTKTLVHDAQQHTDFVRAIQRKNEVVNFLRNKNFHNLADMPNIDVIDGQAEFI
                     NNHSLRVHRPEANLEIHGEKIFINTGAQTVVPPIPGITTTPGVYDSTGLLNLKELPGH
                     LGILGGGYIGVEFASMFANFGSKVTILEAASLFLPREDRDIADNIATILRDQGVDIIL
                     NAHVERISHHENQVQVHSEHAQLAVDALLIASGRQPATASLHPENAGIAVNERGAIVV
                     DKQLHTTADNIWAMGDVTGGLQFTYISLDDYRIVRDELLGEGRRSTDDRKNVPYSVFM
                     TPPLSRVGMTEEQARESGADIQVVTLPVAAIPRARVMNDTRGVLKAIVDNKTQRILGA
                     SLLCVDSHEMINIVKMVMDAGLPYSILRDQIFTHPSMSESLNDLFSLVK"
     gene            11084..11320
                     /locus_tag="RHX21_003739"
     CDS             11084..11320
                     /locus_tag="RHX21_003739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414837.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HDV1988863.1"
                     /translation="MFKKSVLFATLLSGVMAFSTNADDKIILKHISVSSVSASPTVLE
                     DAIADIARKYNASSWKVTSMRIDNNSTATAVLYK"
     gene            11332..11925
                     /gene="rclC"
                     /locus_tag="RHX21_003740"
     CDS             11332..11925
                     /gene="rclC"
                     /locus_tag="RHX21_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414835.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reactive chlorine species resistance protein
                     RclC"
                     /protein_id="HDV1988864.1"
                     /translation="MEKYLHLLSRGDKIGLTLIRLSIAIVFMWIGLLKFVPYEADSIT
                     PFVANSPLMSFFYEHPEDYKQYLTHEGEYKPEARAWQTANNTYGFSNGLGVVEVIIAL
                     LVLANPVNRWLGLLGGLMAFTTPLVTLSFLITTPEAWVPALGDAHHGFPYLSGAGRLV
                     LKDTLMLAGAVMIMADSAREILKQRSNESSSTLKTEY"
     gene            complement(12085..12954)
                     /locus_tag="RHX21_003741"
     CDS             complement(12085..12954)
                     /locus_tag="RHX21_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308365.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDV1988865.1"
                     /translation="MEFSVLSNNLKMPMMGFGVFQVTDKNVCKQSVLNAIRTGYRLID
                     TAAVYGNEDAVGEAVREAISEGLCTRDELFITSKLWVQDMLNQDTAAAGIEASLKKSG
                     LEYFDLYLLHQAMRDYFSAWRALEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKPMV
                     NQVELHPYFAQPEALATMKYYNVQPEAWAPLGGGRHKPFENNLLQSIADAHQKSISQV
                     ILRWNIQRGVVVIPKSTHQQRIEENFAIWDFSLTEKEMAQISSLDLGYVGESVKHFNP
                     EFVRGCLAVKIHD"
     gene            13203..>13914
                     /locus_tag="RHX21_003742"
     CDS             13203..>13914
                     /locus_tag="RHX21_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308364.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDV1988866.1"
                     /translation="MIRQKILQQLLEWIECNLEHPISIEDIAQKSGYSRRNIQLLFRN
                     FMHVPLGEYIRKRRLCRAAILVRLTAKSMLDIALSLHFDSQQSFSREFKKLFGCSPRE
                     YRHRDYWDLANIFPSFLIRQQQKTECRLVNFPETPIFGNSFKYDIEVSNKSPDEEVKL
                     RRHHLARCMNNFKTDIYFVSTFEPSTKSVDLLTVETFAGTVCKQTDSEMAKEWTINRG
                     LYASFRYEGEWERYPEWSR"
BASE COUNT         3864 a         3221 c         3119 g         3710 t
ORIGIN      
        1 acattttgaa tcaaaatgtc aggttttgta gcaatggcgt ggacgagtct gaatgaagaa
       61 gcctctggtt attatcagtg cctgtcagtt caccaggctg gcactggagt ctctcatccc
      121 agcggacagg tatatcgtgc gggtgtacag caacgtcact acagaggttg aattcgtttt
      181 aaagacctcc tgtggctacc tgttggctga tatcccttcg cttccttcgg gggagttagt
      241 tcttctggct tgtcttgtcc gcttgcggag tgatgccggg caatggcaag tctgcctgac
      301 cggtgactcc gactggttcg ataatgctcc tgcttcaagt ctgtataacg gcttcccaca
      361 tatcggcacc ttgctgaaag cgagtcgtta tcagaatcaa attatccgct ggttactacg
      421 tcctttaccc ggcgatatga gtgatttctg gctcctgact gcacgggagt taagcgtgct
      481 taagattctg atgcagggca tgagtttcag tgagattgcc cgttatgaac aacgcagttc
      541 aaagactctg catgcgattg ccacacaggc attaaggaaa cttggactgg gaacactaag
      601 cgatttcagg ctgctctata caggatgcgg tgacagcaga gtcaaacgga atatacggct
      661 acatgcaaga tatgtcggac aacattccgc tcatcgactc actcagtatg tgcagaacat
      721 ggtgtccgga attctttatc cagagaaagt tatcgttggt aaatcaataa attctgacgc
      781 catatccgga aaagtgcttt ccgggcaaag aaaacatatg tctaaaaaaa gaccaggagt
      841 gttatgacac agcagcgttg ttactaccac ccactgcggc gcgtacggac tcgctacagt
      901 gtaggggcca aaatatttct actgctctgg gctgcaggag tgggaggcac gctgtacagc
      961 ctgtacagcg tgctggcgta ctgacatctg tgagggaagg atgcgtttcg ttcttttctg
     1021 tccctcagga attgtacctg cacagtttga agctctatca accggttctg tctgcaatat
     1081 tacctgcatc agaacagaag aagagttacg caataaattg cggcacaggc cgcagagtgt
     1141 cgtgatatcg gcagggcgac ctgccgaatg cgctgaaatg tggttccgat tttatcggga
     1201 tcactcattc gtggtggtgt tgtgcgtcgc gccctttttt ctgccaccgg atgtgagtat
     1261 ttctggcgtt ctcaaaaacc tgaggttact gaaaacagga atgtcagtag agcgtgctat
     1321 cagtgttgca aatgcctctg gtgggttttc aggactgaaa catgcagaaa atttgccagt
     1381 tatggacagt tactctgtct ttatgaatga ggtgaataac cgcacaaaga caatcgtcat
     1441 gtcagaacgc ttcccggaaa agcaaaagaa ggtgttgtcg ttgcttcttg ctggacacag
     1501 ctgggaatac agtgcgcagt ttctcaaaac ggggataaga cagatatggc ttgctgagca
     1561 gtcgctaaaa aagcgttggg gaataccgga cagcatgtca ttgcgggaag ccctgctgct
     1621 gagcagcaat aaatttcacg gtgatggaaa tgcattggaa aaaacgaatg ccatgacatt
     1681 gcgtgaaaac ggaaatacca acaggtattc cgtggtggta aatgcaggga cgcaggcttt
     1741 atctctgcat aaatataaat aagtgggaaa ttgaaattag ttaccagaat ggagaatttc
     1801 ttcatgaaaa acagtaaggc attttaccgc agcgcattag cgacagctat tgttatggct
     1861 ctttctgcac cagcattcgc tgctgataac gcggtatcaa ctacaccggt tacactggat
     1921 aaagataaga caactctgga tcaagatgtt gttattagca atacagcaga ccaacagatt
     1981 acagccgtaa caattaatgc ggcagataaa gatcttaatg ttacttttgg cggtcatgat
     2041 attactgctg aatcaacggc agacaaaaaa ttccttgaag gtgtaaaagt tagcggtgac
     2101 aaaaatgttg tgattaatgc tacaggctcc accatcacag ctcaaggtga aggcacctat
     2161 gtccggactg caatggtcat ttcttcaact ggcgatgttg ttgttaatgg cggtaatttc
     2221 gttgcaaaaa atgaaaaaag tagtgcgaca ggaatatctc tggaaggggc cacgggaaat
     2281 aatgtaacgc taaatggtac aaccataaat gctcaaggta ataagagttc cagcaacggc
     2341 tctacggcaa tttttgctca aaagggtagc gtattgaatg gttttaaagg tgatgcaacc
     2401 gacaacatta cccttgctgg ctcaaatatt attaatggcc ggattgaaac aatagttatt
     2461 gccaaggaga atacgggaac tcatacagtc aatctgaata ttaaggatgg ctcagtaatt
     2521 ggggcggcta ataataaaca aacaatttat gcttctgctt cggcacaagg agcaggttca
     2581 gcaacgcaaa atttaaattt atctgtcgcc gattcaacca tctactctga tatccatgcc
     2641 ctttctgcaa gcgagaattc agccggtacc acaacaaatg taaacatgaa cgttgcccgc
     2701 tcttactggg aaggtaatgc ttataccttc aatagcggcg ataaagcggg tagtaatctg
     2761 gatataaatc tttccgatag ctcagtctgg aaaggcaaag tttcaggggc aggagatgcc
     2821 agtgtatctc tgcaaaacgg gtctgtctgg aatgttacgg gatcctcaac tgttgatgct
     2881 ctggcagtaa aagacagtac ggttaatatc acgaaggcta cagtcaatac tggcacgttt
     2941 gcttctcaga acggcactct gattgttgat gcctcttctg aaaacactct ggatatcagc
     3001 ggaaaagcga gcggtgactt gcgtgtttac agtgcgggtt cattggatct tatcaatgaa
     3061 caaacggcat ttatttctac cggcaaagac agcactctaa aagccacagg cacaacggaa
     3121 ggtggtctgt atcaatatga cctgacacag ggagctgatg gtaactttta tttcgtaaaa
     3181 aacacgcata aagcatccaa cgccagctcc ctgattcagg caatggcagc agctccggct
     3241 aacgttgcta atctgcaggc tgacacgctc tcagcccgtc aggatgctgt ccgtctgagc
     3301 gaaaatgaca agggcggcgt atggattcag tactttggcg gtaaacagaa acataccacc
     3361 gcgggaaatg catcctatga cctggatgta aacggtgtaa tgctgggtgg tgatacccgc
     3421 ttcatgactg aagatggtag ctggctggca ggtgtagcga tgtcttctgc gaaaggtgac
     3481 atgaccacca tgcagagcaa aggcgacact gaaggttaca gcttccacgc ttacctgagc
     3541 cgccagtata acaacggtat cttcattgat actgctgcac agtttggtca ctacagcaac
     3601 acggcagatg ttcgcctgat gaatggtggc ggtaccatca aagctgactt taacaccaat
     3661 ggtttcggtg cgatggttaa aggcggttac acatggaaag acggtaatgg cctgtttatt
     3721 cagccatatg ccaaactgtc tgcgctgacg ctggaaggtg tggattatca gctcaacggc
     3781 gtggacgttc attctgacag ctataactct gtgctgggtg aggccggtac gcgcgtgggt
     3841 tatgacttcg ctgtgggcaa ctcgaccgtt aaaccttatc tgaatctggc cgcactgaac
     3901 gaattctctg atggcaacaa agtccgtctg ggtgatgagt ctgtcaatgc cagcattgac
     3961 ggtgcagcat tccgcgtggg tgcaggtgta caggctgata tcaccaaaaa catgggagca
     4021 tatgcaagcc ttgactacac caaaggtgac gacattgaga acccgctaca gggtgtagtt
     4081 ggtatcaatg tgacctggta agaataaagc agtcggttcc cctgtcgact gttatacccc
     4141 ctgcaggcag catactgctg cctgcaggct ataaacatcc agtattcatg atgctggttt
     4201 tttgctgata tttaccccga acattcctga tacagactat taatacaacc ttatctgcga
     4261 cagattttat tttctggata tattatgcgt gaacaaatca aacaggatat cgatctgatt
     4321 gagattttat tttatctgaa gaaaaagatt cgcgttatcc tttttattat agctatctgt
     4381 atggcaatgg tgctgttgtt tctgtatatc aataaagata atataaaagt gagttacagc
     4441 ctaaaaataa accagacaac accaggcata cttgttaact gtgatagcaa taataacttt
     4501 gcctgtcaga ccacaatgac tgaagatgtt atacagcgaa ttactacatt ttttcacacc
     4561 agcccagatg tcaagaacag agaaataaag ctggaatggt caggagataa gagagattta
     4621 ccaactgctg aagcggaaat atctcgcgtg caggcgtcta ttatcaaatg gtatgcgtca
     4681 gaataccata atggcaggca agttctcgat gagatacaaa caccttcagc aattaacagt
     4741 gagctttata caaaaatgat atacctgacc aggaactggt cattgtatcc gaacggtgat
     4801 ggctgtgtaa ctataagctc accagaaata aaaaataaat accctgctgc catttgcctg
     4861 gctctgggat tttttctaag cattgtaatt tctgtaatgt tttgccttgt caaaaaaatg
     4921 gtagatgaat accaacaaaa ctctgggtag taataaacag cattctgata gagagtgcct
     4981 gtataaagct gaagtgacaa tgaccgggaa gggaacccgt tttcaggaat ggatgcctgt
     5041 ctttttcact gtaaatatcc tggcattact aatgccagga tatttacaga agagcagcat
     5101 aaccatgacg gaacggggtt aagtcaggtt gtcctaaacg ctattttcaa cctcgtatgc
     5161 cttcttcagg tttatgtcca gacttcatat ctctctcaac aatcctcaat aatcagatac
     5221 accgctttca ccggaccatg aaccccgacg actttgataa gctcaatatc cgccgttgaa
     5281 ctagggccgc taatgatgtt aatgcaggac ggcattcgtt caccggcctg cgctttctga
     5341 tgcaattttt ctgcgagttg cgctacacgc ggcaagatag tgcttttacg caggataaaa
     5401 agagaagatt ccgggagcag gctcaatgaa cgcccgcgcc cggcggcgga aaaaagaacc
     5461 acgcctcccg attcggttaa accatattca gcatacacga cacccacttt agcctgctct
     5521 gcctgcgaga tattctcggc acctttcgcc ggatcccaaa caacggcatt gcattcctgc
     5581 tgcaaacgtt cgctaatccc caattcctct agcctcgtgt caccgctaat cacgaccgac
     5641 tgatctccca gctctttaca cagacgtatt gcagcttctg ccgccttcgc ctcgctggtc
     5701 agctcacagc gcgtcaacat aacatcgctg gcaaactgaa taaacgcgtc acagcgctgc
     5761 tgttggttaa gtgcggtaag ccgctcgtta gcatagttgt taagcggcgc atcttctgct
     5821 tgcggttcaa gtcgcaacgg gcgacccagt gcctgagcaa cgttattcaa aaattcgctc
     5881 cgattatcca ttctttttct cctgcgccag atgtttctta aaccaactac ggaaactctc
     5941 tccgtcagct tcaggaagat cgcgtgcttc catccagtca ctaatcgcgc caaatttgag
     6001 tggtgttttg ccgccattga taaaccagct tgccgcatga gcaccggcca tcatcccgac
     6061 tttccacaat cctggatgac tattggcata agcgaacatt tttatcgccc gttgctctgc
     6121 ttttgcggtg atcccttttt cagccatcac ccgacgatga cgcaaaatca gttttgacag
     6181 cggaatacgc accggacaca cgctgtcaca agcagtgcat aaagagcagg cgtagggtaa
     6241 atctttaaaa tctttatagc cgccaagtag cggagaaatc accgcaccaa ttggccctgg
     6301 ataaatagag ccatatccat gaccgccaat atggcgatat gccggacaag tattcataca
     6361 agccccgcag cgaatacagc gcagcacatc ccgaaattca gaggccagca cctcagaacg
     6421 cccgttatcg acaataacca gatgaaactc ttcaggacca tcaacgtgcc ccgcttcgcg
     6481 cggtcctgtc agccaggtgt tgtatcccgt caaacgtgca ccaacggcac tgcgcgccag
     6541 catggtgatc aatacatcta cctcggcaaa cgtgggggca atacgctcca ttcccatcac
     6601 tgcaatatgc gttttaggca gcgtggtaca cattcgcgca ttaccttcat tggtcaccag
     6661 gcataccgaa cctgtctctg ccaccgcgaa attacagccg gtaataccta tttcagcact
     6721 gaggaaatct tcgcggattt tttgccggat gaataaggtc atcgcttcag gcgtttccgg
     6781 cccctcatag cccagaagtt cgtgtagcac tcgacggatc tgatggcgat ctttatgaat
     6841 tgccgggacc acaacatgag agggcggatc ttgatccagc tggagaatgt attcacccag
     6901 atcggtttca atcacctgaa tgccagcatc ctgcaacaca tgattgacac caatctcttc
     6961 ggtcaccatc gatttagatt tcaccacctt ccgggcattt ttgcgttggg caacctgtaa
     7021 aatgtagcga gtggcgtctt ctttagtttt tgcaaaatag acgtgaccgc cgttttgcgt
     7081 cactttttct gagagctggt acagataagc gtcgagatta ctcagaacat gatcacgtat
     7141 ctgggcggcc cgatcgcgcc actcctccca gtgccccaat tcatcgacca ttttttgccg
     7201 atttgcccca atacgctgct gcgcgtttgc caccgctttg cgcatgatcg gatcttcaat
     7261 ttgctgacgg atgcgtgtct taaaatctgt attactggtt ttgatcgaca tctttatatc
     7321 ctcagcggct catcaacact tcagcaatat gcatcacttt gactttctgc ccttcccgtt
     7381 gtaatcgccc actgatgttc agcaggcaac tcacgtcagc accaattaaa tactcagggc
     7441 ggacttccat caggtgcaca accttttctt tcaccatctc gccggatatt tcggccattt
     7501 tgaccgagaa cgtgccgcca aatccgcagc aggtatcctg ttcagcaaag gtcaacagct
     7561 ccagtccacg cacatttttc agcagcgtaa gtggttcgtc cttcaccccc agcttacggg
     7621 ccaggctaca agatgggtga tacaccgctc tcccttgcaa actggcacct acatcgacta
     7681 cccctaattt attaacaata aaagaggtga gatcctgcat acgcgcggca accttttcgg
     7741 ctcgtgatgc ccattcaggt tcatccgcca gatacatcgg gtaacttttt acggcatagg
     7801 tgcaggagcc agccggtgaa ataatgggat catcgttatc ctccagtgcg gcgatcagat
     7861 ttttcatccc tggaatcgct tctttgatat aaccactatt gatcgcaggc tgaccgcagc
     7921 atccctgttt ctccgggaaa tttacgcgac agccgagttt ttccagtagc agcacggagt
     7981 ctcgtgccat tcttgatttc agggcgtcac caatacaggt gacaaagaaa ttgacattca
     8041 caactaatac tccattactt catgcccatt tatgcccgat gtttcccccc caccggggga
     8101 tcaatcatca ataaatatgg cgttcttttt taattggcta gcaacatacc acccctcatt
     8161 tgtatgacaa atgatgatct ttcatccaaa cttcaaatgc aataactaat tttatttctt
     8221 tcggcatcgc tcacatttta tagggaaatc gacgatcatt tttggcataa gaaatccatt
     8281 taaaaatggc tacatccctt atacctattc agagctactt attcaggggt tattgagata
     8341 tacactgatg gtgtacaaac aaaatcaccg acaataatca cgtatcaagt aatagtcggg
     8401 gttttattta attgaagcaa tttagtttgc atttttattt aaaaactgag ctagagtcca
     8461 tcagaaaaaa atatataaag cccaaaccac cgttggaaat agaaatagtt gaaaggctca
     8521 caactcccgg aatgcggatt atctttgccc tgatttctgg cggttttatt cagggtgcaa
     8581 gctgtctgac cctttcccga tattctcccg gagtacaacc aaactcgcgg acaaacgcct
     8641 tgtgaaaaga tgattcactg gcatagccta ctgactcagc gatcaccaca acagggagca
     8701 tttcccggga aaacatctgg gccgctattt gtagacgcaa ctttgttaat acagccagcg
     8761 gcgtggttcc ggaaacatca cggaaaagct gggcaaaact tgcccgggac atgtgagcga
     8821 tgctggccag cgattcgacg gtccaggcgt gtcctggcat ttccagcatt tgctgtatta
     8881 ccgcaccaag acgtggatgc agaagcaaac tgagaatgtt tttctcagta ttaacctgtg
     8941 caatccactc acgcaccgcg agggtaaaga atgtagcgca gatctggcta cacagtgcat
     9001 ccactcccgg catcgccgat ctggattcct gttgtaaaaa cgggatcgcc tccctcagcc
     9061 agttatattc cacgctgtgg ttaaccggtg ctaaaaacag cgtttccggc aaagacgtta
     9121 aaaaataacg cgccgaatgt tgcaaccgaa gagtgccgca gacaatacag gtcgattcat
     9181 tatcgacatg actcaggcga tgagctgaat tttgtggtag caggaccaca tttcccgggc
     9241 gtaatgtaaa aatctctccc gtcggcattt ccagcttcgc cgctccttgc gttaacgcat
     9301 gccaacgaat aaccgataat tccccggcac catgtggaag ctgccagtca cttcctaaca
     9361 cgcaattctt atcgatcgtt ccttgtggag cgttaagcat caacaaacgg ctaagggcat
     9421 ccatatcaga ctcctgagtg gtttttgatt acaaacacca acaatcttag taaataacta
     9481 atctaatacc atcaaatggt taatcatgat ttttgttttg tgattctgat taagaaaaag
     9541 aaaataccag acgataagac aaaatatcaa gcgttgtgaa gaaatggtat ttgctctttt
     9601 gcgtctatag tcatgatgtc aaatgaacgc gtttcgacag gaaatcatca tgaataaata
     9661 tcaggcagtt attattggtt ttggcaaggc tggaaaaaca ttagccgtca cgctggcaaa
     9721 agcaggttgg cgagtggctc tcatcgaaca atcaaatgca atgtatggcg ggacctgtat
     9781 taatatcggc tgcatcccaa ccaaaacatt ggttcatgac gcacagcagc acacagattt
     9841 tgtccgtgcc atacagcgta aaaatgaagt ggttaatttt ttacgtaata agaattttca
     9901 taatcttgcg gatatgccca atatcgacgt gatcgacggc caggcggagt ttatcaataa
     9961 tcatagcctg cgtgttcatc ggcctgaggc aaatctggaa attcatggcg agaaaatttt
    10021 tattaatacc ggtgcacaaa ccgtggttcc gccaattcct ggaattacca ccacgccagg
    10081 agtatatgac agcaccggat tacttaatct aaaagaattg cctgggcatt taggtatttt
    10141 gggcggcgga tatattggcg ttgagttcgc ctctatgttc gctaattttg gcagcaaggt
    10201 aaccatttta gaagcagctt cgctgttttt gcctcgggaa gatcgggata ttgctgataa
    10261 tatcgcgacg attttacgcg atcagggcgt cgatattatc ctcaatgccc atgtggagcg
    10321 aatcagtcac catgaaaatc aagtgcaagt gcatagcgag cacgcccaac tggcggtgga
    10381 tgcactgtta atagcttccg gtcgtcaacc ggctaccgct tcgttacatc cagaaaatgc
    10441 cggtatcgca gtaaacgagc gcggggcaat tgtcgttgac aagcaattac ataccaccgc
    10501 agacaatatt tgggcgatgg gagatgttac cggcgggctg caatttactt atatttcact
    10561 ggatgattac cgcattgtgc gtgatgagtt gctgggagaa ggcagacgta gtactgatga
    10621 tcggaaaaat gtgccttatt ccgtattcat gacaccgcca ctgtccaggg ttggtatgac
    10681 agaagaacag gccagagaga gtggtgctga tattcaggtg gtgacattgc ctgtagctgc
    10741 aattccgcgt gccagagtga tgaatgatac tcgtggggta ttaaaagcga ttgttgataa
    10801 taaaacccaa cgtatattag gggcatcact gctgtgtgtt gactcccacg agatgatcaa
    10861 tatagtgaaa atggtgatgg atgccgggct gccttatagc atattacgcg atcagatatt
    10921 tactcatccg tcgatgagcg aatcactcaa tgatctattt tcattagtca aataaactca
    10981 aaatcagacg ccagaacaaa tattctggcg tctcagagaa aagaatctta ttaattccct
    11041 gttactctat aacttcttaa tcacttcatt gatggtattt tatatgttta aaaaatctgt
    11101 tttatttgca acactattat ctggcgttat ggcattttcc accaatgcag atgataaaat
    11161 aattctgaaa catatcagcg tctcgtcagt atcagcatca ccgacagttc tggaggatgc
    11221 cattgctgat atagccagaa aatataatgc ttcatcctgg aaagtcacat cgatgcgaat
    11281 tgataataat tcaaccgcaa cagcagtatt gtataaataa ggatgttcac aatggaaaaa
    11341 tacctgcacc tgttaagtcg gggagataaa attggcctga cattgattcg tctgagtatt
    11401 gcaattgttt ttatgtggat tgggttatta aagtttgtcc cttacgaggc agacagcatt
    11461 acaccattcg tcgcaaacag tccactaatg tcgttctttt atgaacaccc ggaagactat
    11521 aaacagtatc tgactcacga aggcgaatac aaaccagaag caagggcatg gcaaacggcc
    11581 aataatacct atggtttttc caacggtctt ggcgtcgtgg aggtgattat tgctctgctg
    11641 gttttggcta atcctgtcaa tcgctggtta ggtttattgg gaggactgat ggcatttacc
    11701 acgccgctgg taacactctc atttttaatc accaccccgg aggcatgggt acccgcattg
    11761 ggtgacgctc atcatggttt cccttattta tccggtgctg gtcgcctggt attgaaagat
    11821 actctgatgc tggcaggtgc tgtcatgata atggcagatt cggcgcggga aattcttaaa
    11881 caacgcagta atgaatccag ttcaacgtta aaaactgaat attgataatc cgaacactgt
    11941 ctgttgttca ctttttcagg cgtcaggccc cctttctgat gatgaagcct gacgccatat
    12001 taccggagat atgacagagt gaagatcaat atcactcccc ggttaaaaga ttcttgtcgt
    12061 ctcaggtaaa atatatgatt aatatcaatc gtgtattttt acagcaagac aaccacgaac
    12121 aaattcagga ttaaaatgtt ttaccgactc cccaacataa cccaaatcaa gcgaactaat
    12181 ttgtgccatt tctttctctg tcagtgagaa atcccagata gcaaaatttt cttcgatacg
    12241 ctgttgatgt gtcgatttcg gaataacgac cactccccgt tgaatattcc aacgcagaat
    12301 gacttgagaa atcgattttt gatgggcatc tgcaatactc tgaagcagat tattttcaaa
    12361 gggtttatgt cgtccaccac ctaacggagc ccatgcttca ggctgcacgt tataatactt
    12421 catggttgcc agcgcctctg gttgggcaaa atagggatgc aactcgacct ggttgaccat
    12481 cggtttaact cttaccgttt cacaaaagtt cgccagaaca tgaggataga aattggaaac
    12541 cccaattgct tttaatttgc cctcttcata ggcatcttcg agtgcacgcc acgcactgaa
    12601 ataatcgcgc atagcctggt gcaataaata gaggtcgaag tactctagtc ccgatttttt
    12661 taatgatgct tcaatacctg ctgctgccgt atcctgattc aacatatcct gcacccacaa
    12721 tttagacgtt ataaataact catctcgggt acataaacct tcagatatag cttcacgaac
    12781 ggcttcaccg acggcatctt cattaccgta taccgctgca gtgtcgatga gtcgataacc
    12841 tgtgcggata gcgttcaaca ctgactgttt gcacacgttt ttatcggtaa cctgaaaaac
    12901 accaaatccc atcatcggca ttttcagatt gttacttaat acggaaaatt ccactgtcag
    12961 tccctccatt aggcatgaac aatgagtcta cgttaaaacg taacctcaaa ttagtacgtg
    13021 gattttgata tcacttatgc aaaaaaatca ttaataatgc aggactgaaa cctctctatt
    13081 ttcggggaca acgaagcaga cgctaccagt gcttttgcct tcgcccttgc tgtttttgat
    13141 acacttaggg cccagggcat aacgaaaatg tgcgatatga caaagaatta acggagaatg
    13201 tgatgatcag gcagaagatt ctacagcagc tcctggagtg gattgagtgc aatcttgagc
    13261 accctatttc aatcgaagat atcgcacaga aatctggcta cagcagacgc aacatccagc
    13321 ttctgttccg aaatttcatg catgtgcctt tgggagaata cattcgcaaa cgaaggcttt
    13381 gccgtgccgc tattcttgtc cggctcaccg cgaaatctat gcttgatatt gcactctctt
    13441 tgcattttga ttcacagcag tcattcagcc gcgaatttaa aaagttattc ggctgctctc
    13501 cccgtgaata ccgccaccgt gattattggg atctcgcaaa tatcttccct tcttttttaa
    13561 tacgtcaaca gcaaaagacg gagtgtagat tagtcaattt tcctgagaca cctatttttg
    13621 gcaactcatt taaatatgac attgaagtgt cgaataaatc accggatgaa gaagtcaaac
    13681 tgcgacgtca tcatttagcc agatgtatga ataattttaa gacggatatc tatttcgtct
    13741 ccacgtttga accgtcaaca aaatcggtcg atttgctcac agttgaaact tttgccggta
    13801 cggtatgtaa acaaaccgat tctgagatgg cgaaagagtg gacaataaac cgaggactgt
    13861 atgcatcttt ccgctatgaa ggtgagtggg agcgctatcc tgaatggtcg cgaa
//
LOCUS       DAPGUL010000118        13653 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.120, whole genome shotgun sequence.
ACCESSION   DAPGUL010000118 DAPGUL010000000
VERSION     DAPGUL010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13653
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.120"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            320..814
                     /locus_tag="RHX21_003743"
     CDS             320..814
                     /locus_tag="RHX21_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1441 family protein"
                     /protein_id="HDV1988867.1"
                     /translation="MDRELKNLTLNISQLAALSGVHRQTAAARLQNLPVAGGHESNLK
                     LYRVVDIVSAFLALPPPVAEGEMDAHERKAWYQSERERLKFEQETAQLIPASDVRREF
                     AIWAKAVVQVLETLPDILERDCGLQPAAVSRVQSIIDDLRDQIALRVTEAGADDEEEL
                     QQEE"
     gene            814..2916
                     /locus_tag="RHX21_003744"
     CDS             814..2916
                     /locus_tag="RHX21_003744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit family protein"
                     /protein_id="HDV1988868.1"
                     /translation="MLNQETAKAARTDSGYILRAPRRMRVADAVAQYMRVPMGAGNSV
                     PWDPLVAPYVIEPMNCLASREYDAVIFVGPARTGKTIGLIDGWVIYNVICDPADMLII
                     QMTEEKAREHSKKRLARTFRVSPEVVSRLSPNKNDNNVYDRTFLAGNYLKIGWPSVNI
                     MSSSDYKCVALTDYDRFPEDIDGEGDAFSLASKRTTTFMSSGMTLVESSPGRDVKDVK
                     WRRTSPHEAPPTTGILSLYNRGDRRRWYWPCPHCGEYFQPCGDVVAGFRDIADPVLAS
                     EAAYIQCPSCSGRIMPEQKRELNGRGVWLRDGESINADGSRYGDPRRSRIASFWMEGP
                     AAAYQTLSQLVYKLLTAEQEYETTGSEETLKTVINTDWGLPYLPRASMEQRKSELLEQ
                     RAEPVPSRSVPDGVNFLVATVDVQAGRHRRFVVQVTGYGSRGERWIIDRYNITQSLRG
                     DCDGESQRIDPASYPEDWDVLLTDVFHKSWPLASDPSQQMRLMAMAVDSGGEDGVTDN
                     AYKFWRRCRRDGLGKRIYLFKGDSIRRAKLISRTFPDNTGRTGRRAQAAGDVPLWLLQ
                     TDALKDRVNNALWRDSPGPGYVHFPDWLGSWFYDELTYEERSSDGKWSKPGRGANEAF
                     DLMVYAEALVILHGYEKIRWPDAPEWASRETWLECVPDSTEPSSSPEPVSTPVKKQKR
                     KKTVTDDVNPWLTSGGWL"
     gene            2913..3125
                     /locus_tag="RHX21_003745"
     CDS             2913..3125
                     /locus_tag="RHX21_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988869.1"
                     /translation="MNQNDIEAMIQRYTEAEMAVLDGKSVTFNGQQMTMENLSEIRQG
                     RQEWERRLAALITRRRGHPGYRLARF"
     gene            3053..4633
                     /locus_tag="RHX21_003746"
     CDS             3053..4633
                     /locus_tag="RHX21_003746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011703754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDV1988870.1"
                     /translation="MGAPPCGSDYTTTGASRVSAGEVLMAILDDVIGVFSPGWKAARL
                     RSRAVIQAYEAVKTTRTHKARRENRTADQLSQYGAVSLREQARYLDNNHDLVIGVFDK
                     LEERVVGKNGIIVEPHPVLRNGAIARDLAAEIRTRWSEWSVSPEVTGQFTRPMLERLM
                     LRTWLRDGEVFAQMVSGRINSLTPSAGVHFWLEALEPDFIPMTSDESNRLNQGVFVDD
                     WGRPEKYLVYKSRPVSGRQMETKEVDAERMLHLKFVRRLHQMRGTSLLSGVLIRLSAL
                     KEYEDSELTAARIAAALGMYIRKGDGQSYEADGNGSKDKERELTIQPGIIYDDLKPGE
                     EIGMVKSDRPNPNLETFRNGQLRAVAAGSRLSFSSTARNYNGTYSAQRQELVESTDGY
                     LILQDWFIGAVTRPMYRAWLKQAVASGVIRLPRDLDLSSLYTAVYSGPVMPWIDPVKE
                     AEAWKIQIRGGAATESDWVRAGGRNPDDVKRRRKAEIDENRKLDLVFDTDPASDKGGS
                     SAATKRQEPQHTDDQSEE"
     gene            4578..6605
                     /locus_tag="RHX21_003747"
     CDS             4578..6605
                     /locus_tag="RHX21_003747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308856.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HDV1988871.1"
                     /translation="MPQRNDRSRSTPTTSPKNNSWFRMQAGHQSDADIYIYDEIGFWG
                     VTAKQFISDLNALGDITHINLHINSPGGDVFEGIAIFNALKTHGASITVYVDGVAASM
                     ASVIAMVGNPVIMPENTFMMIHKPFGFTGGDAEDMRTYADLLDKVEAVLLPAYAQKTG
                     KTTDEIAAMLADETWMSGAECLAHGFADQVTPAVKAMACIQSKRTEEFKKMPESIRNM
                     ITPPRNSAPRVQDNEPEASRTPVQAAAPVVDENSIRAQVLAEQKARVNGINDLFAMFG
                     GRYQTLQAQCLADPECSLEQAREKLLNEMGRESTPSNKNTPAHIYAGNGNFVGDGIRQ
                     ALMARAGFEKTERDNVYNGMTLREYARMSLTERGIGVSGYNPMQMVGAAFTHSTSDFG
                     NILLDVANKAILQGWEDAPETYEQWTRKGQLSDFKIAHRVGMGGFSALRQVREGAEYK
                     YVTTGDKQATIALATYGELFSITRQAIINDDLNMLTDVPMKLGRAAKSTIADLVYAIL
                     TSNPKISTDNVSLFDKAKHANVLESAAMDVASLDKARQLMRVQKEGERHLNIRPAFVL
                     VPTAMESVANQVIRSSSVKGADINAGIINPVKDFATVIAEPRLDDNSQTTFYLAASKG
                     SDTIEVAYLNGVDTPYIDQMEGFSVDGVTTKVRIDAGVAPVDHRGLVKCTA"
     gene            6692..7015
                     /locus_tag="RHX21_003748"
     CDS             6692..7015
                     /locus_tag="RHX21_003748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308857.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2190 family protein"
                     /protein_id="HDV1988872.1"
                     /translation="MAKNFVEEGKTVAIVASAAISSGDLVQVGDVFAVALTDIPQGET
                     GDGMTEGVFMLPKLKTDDMKTGKKVYLKSGKVQLTNSGSDPLVGVVWADAGTSAEEVP
                     VKLNV"
     gene            7008..7283
                     /locus_tag="RHX21_003749"
     CDS             7008..7283
                     /locus_tag="RHX21_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA breaking-rejoining protein"
                     /protein_id="HDV1988873.1"
                     /translation="MSDPFSRLAARMDAITVRKMGKTASINDADMTVIPGETLAELNA
                     LSGPAVSLVVFSSGYRPRRGDRVVYDGQQWTVTRHERFNGKPMIFIE"
     gene            7295..7873
                     /locus_tag="RHX21_003750"
     CDS             7295..7873
                     /locus_tag="RHX21_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV1988874.1"
                     /translation="MKGLENTIRNLNSLDTRMVPQASAWAINRVAQKAVSVATRQVAG
                     NTVAGDNQVKGIPLKLVRQRVRVFKASPSGKMTARIRVNRGNLPAIKLGTARVRLARR
                     GGKLQYRGSVLKVGKYLFRDAFIQQLANGRWHVMRRIDGKNRYPIDVVKIPLSGPLTQ
                     AFEDARDRIIAAEMPKQLGYALKQQLRLWLTR"
     gene            7870..8271
                     /locus_tag="RHX21_003751"
     CDS             7870..8271
                     /locus_tag="RHX21_003751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV1988875.1"
                     /translation="MNRHTQIRQAVLARLREQCGDSATFFDGLPAFIDAQELPAVAVW
                     LSDAQYTGKMTDEDDWQAVLHIAVFIRAQAPDSELDMWMESTIFPALNDIPALSGLID
                     TLIPLGFNYQRDNEMATWAMAEITYQITYTN"
     gene            8283..9026
                     /locus_tag="RHX21_003752"
     CDS             8283..9026
                     /locus_tag="RHX21_003752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV1988876.1"
                     /translation="MTTPNPLAKTKGAGTTFWMYTGKGDAFANPLSDTDWLRLAMVKD
                     LQPGEMTADAEDDTYLDDEDADWKTTTQGQKSVGDTSATLAWRPGDSGQKKLVQLFDS
                     GEVCAFRIKYPNGTVDVFRGWLSSLGKTIASKDVMTRTVKISGVGRPYLAEEGTETVS
                     VTGLTVAPASASVKVGATTTLTFTVKPDGASDKAISVHSTDPQTATVTLNGLVATVKG
                     VKQGSVSIVGMTSDGDFVAVAAVAVSAAG"
     gene            9087..9473
                     /locus_tag="RHX21_003753"
     CDS             9087..9473
                     /locus_tag="RHX21_003753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein G"
                     /protein_id="HDV1988877.1"
                     /translation="MFLKQGTFNYEKQSVVLSELSGLQRIEYLAFVQQRTAKFDAEEG
                     ELPEAERQIAFLRMGMDINAWLVSRSLWNAEQSQDVETLCASVITTWSYDALGAGAEM
                     VLSLSGMGAIDNAGDLEHEVLTPEKS"
     gene            9482..9811
                     /locus_tag="RHX21_003754"
     CDS             9482..9811
                     /locus_tag="RHX21_003754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein T"
                     /protein_id="HDV1988878.1"
                     /translation="MQFVMRLAREFRRADWRRMLSEMSATELGEWGDYFRMQSFSDVW
                     MDAQFASLKALIVRMVSGSSDAAVADFSLLPEENGIPERTDEELMHLGEGISGGVRYG
                     PDSQPGH"
     gene            9783..12839
                     /locus_tag="RHX21_003755"
     CDS             9783..12839
                     /locus_tag="RHX21_003755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDV1988879.1"
                     /translation="MDQIANLVIDLGIDAAEFKNEIPRIKNLLNGAASDAERSSARMQ
                     RFMERQTQAARQTMQAASSAATAASVHAQTVEKSAQAHERMAREVEQTRQRMEALSQK
                     MREEQAQAMALAEAQDKAAAAFYRQIDSVKQASAGLQELQRIQQQIRQARNSGGIGQQ
                     DYLALISEVTAKTRVLTQAEAEATRQKVAFIRQLKEQATRQNLSSSELLRAKAAQLGV
                     SSAAEVYIRKMEQAGKATHSLGLKSAAARQEIGVLIGELARGNLGALRGSGITLANRA
                     GWIDTLMSPKGMMLGGVIGGIAAAVYGLGKAWYDGQKEGEEFNRQLSLTGHYAGVTAG
                     QLWTLSRAISGNGITQHAAAGALAQVVGSGAFRGNDIGMVARAAAQMERSVGQSVSDT
                     INQFKRLKDDPVNAAKALDNELHFLTATQLEQIRVLGDQGRSSDAARIAMSALAEETG
                     RRTADIDNNLNALGSTLKYLSDLWSRFWDAAMNIGREDSLDEQISALQEKVSRAKRLP
                     WTASSSQVEYDQQRLNELQEKKRQKDLQDAKEQAERNYQEQQKRRNAENAALNRMNET
                     EAARHQREIARINAMQYADQAVRDAAIQRENERYEKALASGKKKTREPRNDEATRLLL
                     QYSQQQAQVEGQIAAARQSAGIATERMTEAHKQLLALQQRISDLDGKKLTADEKSVLA
                     RKDELIQALTLLDVKQQELQKQTALNELKKKTIQLTSQLAEEERAQRQQHDLDIATVG
                     MGDQQRQRYQVQLSLRQKYQQQLEQLRRDSEQKGTYNTDDYRKAEQALTESLNRQLNE
                     NRRYWQQLEVVQGDWKNGVLRALQNVTENADNTAGTVEQLFTSAFSSMSDWLATFCTT
                     GKLNFKSFTSSVLSDMSRIMAQIALMKAVKGIASALPFDFVANADGGVYQSADLSRYS
                     GTVVNRPTFFAFAKGAGVMGEAGPEAILPLRRDADGKLGVVADIGGSGMAMFAPQYNI
                     EINNDGTNGQIGPAALKVVYDLGKKAAADFMQQQARDGGRLSGAYR"
     gene            12839..13168
                     /locus_tag="RHX21_003756"
     CDS             12839..13168
                     /locus_tag="RHX21_003756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV1988880.1"
                     /translation="METFHWKVRPDMNVVSEPKVVTVKLGDGYEQRRAAGLNNQLSTY
                     SVTIRVRKCEHPSLKAFLERHGGVRAFQWTPPYDWKPIRVVCRKWSASVGALWVTITA
                     DFEQVVA"
     gene            13178..>13653
                     /locus_tag="RHX21_003757"
     CDS             13178..>13653
                     /locus_tag="RHX21_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HDV1988881.1"
                     /translation="MQDIPQETHHETTRLTQSAQVVLWEIDLTEVGGERYFFCNEQNE
                     KGEPVTWQGRQYQAYPIQGTGFELNGKGSAARPTLTVSNLHGMVTGMAEDLQSLVGGT
                     VVRRKVYARFLDAVNFVNGNSDADPEQEVISRWRIEQCSELSAVSASFVLSTPTET"
BASE COUNT         3313 a         3153 c         4147 g         3040 t
ORIGIN      
        1 atctttaacg tcctccgcaa atacatcgaa aataatattc actttgtgat ttgtagttac
       61 cttggaaagg tacataacta acgagaatta ctctcatcat tgacgggtcc tcccggtggg
      121 gtggcctgcc acggggcggg agcgtcgcgg aaaaaggcta gtttttgaaa ttttattcgt
      181 catcaccacc actgtaattg attgatatta cagtgatttt atttttatgg tgtcgattct
      241 gattgttttt tgttcatcac taacaccgtt tgcctaaagt tgttcgcaag atgcatgttt
      301 aaaacattct ggagcgggta tggatcgaga gttaaaaaat ctgacgctga atatcagtca
      361 actggcggca ttgtcaggtg tacatcgcca gactgctgcg gcaaggctgc aaaatctacc
      421 cgttgcaggg gggcatgaaa gcaacctcaa gctttatcgg gtggttgata ttgtgtcggc
      481 atttctggca ttaccaccgc cggttgcaga aggcgaaatg gacgcgcatg agcgcaaagc
      541 ctggtatcag tctgaacgtg agcgtcttaa gtttgaacag gaaacggcac aactcattcc
      601 ggccagtgat gtcagacggg agtttgccat ctgggcaaaa gcggtcgtgc aggtgctgga
      661 gacattaccg gatattcttg aacgtgactg cggtctgcag cctgccgctg tgagccgtgt
      721 tcagtccatt attgatgatc ttcgcgatca gatagccctg cgggtgactg aagcaggtgc
      781 ggatgatgag gaggaattac agcaggagga gtaatgctga atcaggaaac cgcaaaggca
      841 gcacgaaccg attcaggtta tatccttcgc gcaccgagac gaatgcgggt tgctgatgcc
      901 gttgctcagt atatgcgggt gcccatgggg gcagggaact cagtcccgtg ggatccgctg
      961 gtggcaccgt atgttattga gcctatgaac tgcctggcct cgcgtgaata cgacgcagtg
     1021 atatttgttg gcccggcacg aaccggcaag actatcggcc tgattgacgg ctgggtgatt
     1081 tacaacgtga tttgcgatcc tgctgatatg ctgattattc agatgacgga ggaaaaagcc
     1141 cgcgaacact ccaaaaaacg actcgccaga acgtttcgcg tcagcccgga agtggtcagt
     1201 cgcctgagtc cgaacaaaaa tgacaacaac gtttatgaca gaacattcct tgctggtaac
     1261 tacctgaaaa tcggctggcc gtcagtcaat atcatgtcct catcagatta taaatgcgtc
     1321 gcgctgacgg attatgatcg ttttccggaa gatattgatg gcgaggggga tgctttctct
     1381 cttgcctcaa aacgtaccac aacatttatg tccagtggta tgacgctggt ggagagttcc
     1441 cccggcaggg atgtgaagga tgtgaaatgg cgacggactt caccgcatga ggctccacca
     1501 accacgggga tactgtcgct ctataaccgt ggcgatcgcc gtcgctggta ctggccctgt
     1561 ccacactgtg gtgagtattt tcagccctgc ggcgatgtgg ttgctggttt ccgtgatatt
     1621 gccgatcccg ttctggcaag tgaggcggct tatattcagt gtccttcctg ttcaggacgg
     1681 attatgcctg aacaaaaacg tgagctgaac ggacgtgggg tctggttgcg ggatggtgaa
     1741 tccatcaatg cggatggcag tcgttatggt gatccccgac gctcacgtat tgcgtcattc
     1801 tggatggagg ggccggcagc tgcttaccag acactctcgc aactcgttta caaactgctt
     1861 actgcagaac aggaatacga gacaaccgga agtgaagaaa cactcaagac ggttatcaat
     1921 accgactggg gattacctta tcttccccgc gccagcatgg agcaacgaaa aagtgaactg
     1981 cttgagcagc gggcagagcc agttccttcc cgcagtgtgc cggatggcgt taattttctt
     2041 gtggcgacag tggatgtgca ggcgggacgt catcgccgtt ttgtggttca ggtaacgggc
     2101 tatggcagcc gtggcgaacg ctggattatt gatcgttaca acatcacgca gtcattgcgc
     2161 ggtgactgcg acggggagag ccagcgaatt gatccggcca gctacccgga agactgggat
     2221 gtcctgctga cggatgtttt tcataaaagc tggccgctgg cctccgatcc ttctcaacaa
     2281 atgcgactga tggcaatggc ggtggactcc ggcggtgaag acggggtcac tgataatgcc
     2341 tataaattct ggcgtcgttg ccgtcgtgat ggccttggta aacgtattta cctgtttaag
     2401 ggtgacagca tccggcgcgc aaaactgatc agccgtacat tccctgataa caccggacga
     2461 acgggccgcc gggcgcaggc cgcaggtgat gtgccgctct ggcttcttca gacggatgca
     2521 ctgaaagacc gggtgaataa cgcgttatgg cgtgactcgc caggtcccgg ctatgtgcat
     2581 ttccctgact ggctggggag ctggttttac gacgaactga cgtatgaaga gcggagcagt
     2641 gacgggaaat ggagtaagcc gggtcgcggt gccaacgaag cttttgacct gatggtgtat
     2701 gccgaggctc tggtcattct gcatggatac gaaaagatcc gctggccgga tgcaccggag
     2761 tgggcgagcc gggaaacctg gctggagtgt gtcccggaca gtaccgaacc gtcatcctca
     2821 ccggaaccgg tatccacgcc tgttaaaaaa caaaaacgga agaaaacagt aactgacgat
     2881 gttaacccct ggctgacttc cggaggatgg ttatgaacca gaatgatatc gaagccatga
     2941 ttcagcgtta tacggaagct gaaatggcgg tgctggacgg aaaatccgtc acctttaatg
     3001 gtcagcagat gaccatggaa aacttatctg agatccggca gggacggcag gagtgggagc
     3061 gccgccttgc ggctctgatt acacgacgac gggggcatcc cgggtatcgg ctggcgaggt
     3121 tctgatggca attcttgatg atgtgattgg cgttttttca ccaggatgga aagcggcaag
     3181 gctgcgttcc cgtgcggtga tccaggctta tgaggccgta aaaacgacgc ggacacacaa
     3241 agcccgacgg gagaaccgaa ctgccgacca gttaagccag tacggggccg tgtcgttacg
     3301 tgagcaggcc cgttaccttg ataacaacca cgatctggtt attggtgtat ttgacaagct
     3361 ggaagaacgg gtggtgggga aaaacgggat tattgtcgag ccacatccgg tattacgcaa
     3421 tggggccatt gcccgtgacc tggctgcgga gattcgcacc cgatggagtg aatggtctgt
     3481 cagcccggaa gtcaccgggc agtttacccg tccgatgctg gaacgtctga tgcttcgtac
     3541 ctggctgcgc gatggtgagg tgtttgccca gatggtttcc gggcgcataa acagcctgac
     3601 gccttctgcc ggtgttcatt tctggctgga ggcgctcgag ccggacttta ttcccatgac
     3661 cagtgatgag agcaacaggc tgaatcaggg cgtgtttgtt gatgactggg ggcgtcccga
     3721 aaaatatctg gtgtataaaa gccgtcccgt atccggacgg cagatggaaa ccaaagaagt
     3781 ggatgcagag cgaatgctgc atcttaaatt tgttcgccgt ctgcaccaga tgcgcgggac
     3841 gtctttattg tccggtgtgc tgatccgcct cagtgccctg aaagagtatg aagattctga
     3901 gctgactgca gcaaggatcg ccgctgctct ggggatgtac atccggaaag gcgacgggca
     3961 gagctatgaa gcggatggta atggcagcaa ggataaggaa cgcgagctta ccattcagcc
     4021 aggcattatt tacgatgatc tgaaacccgg cgaagaaatc ggaatggtga agtcggatcg
     4081 cccaaatcct aaccttgaaa cttttcgtaa tggtcagttg cgtgccgtgg cggcgggcag
     4141 tcgtctgagt ttttccagta cggcacgcaa ctataacggc acttacagcg cccagcgtca
     4201 ggagctggtt gaatccactg atggctacct gatcctgcag gactggttta ttggtgccgt
     4261 cacccgtccg atgtatcgtg cctggctgaa acaggctgtg gcatccggtg ttatcaggct
     4321 accccgcgat cttgaccttt cttcactgta taccgcggtg tattccggac cggtgatgcc
     4381 gtggattgac cctgttaagg aggctgaggc ctggaaaatc cagattcgtg gtggagcggc
     4441 gacagaatca gactgggtac gtgctggtgg tcgtaatccg gatgatgtca aacgtcggcg
     4501 caaggccgaa attgatgaaa accgcaagct ggatctggta tttgataccg atccggccag
     4561 tgataaagga ggcagcagtg ccgcaacgaa acgacaggag ccgcagcaca ccgacgacca
     4621 gtccgaagaa taattcctgg ttcaggatgc aggctggtca ccagagtgac gcggatattt
     4681 atatttatga cgagattggt ttctggggtg ttacagcgaa gcagtttatc agtgatctga
     4741 atgcactggg cgatatcacc catattaatc tccatattaa ttcaccgggt ggcgatgtct
     4801 ttgaaggcat cgccattttt aatgcactga aaacacatgg tgcgtccatt accgtttatg
     4861 tcgacggtgt ggcggcgtca atggcgtcgg tcattgcgat ggtgggaaac ccggtcatta
     4921 tgccggaaaa caccttcatg atgattcata aaccatttgg ctttacgggc ggtgatgcgg
     4981 aggacatgcg cacctatgcc gacctgctcg ataaagttga ggcggttctg ttacccgctt
     5041 atgcacagaa aaccgggaaa accaccgatg aaattgctgc catgctggcg gatgagacct
     5101 ggatgtccgg tgccgaatgt ctggcacatg gatttgctga tcaggtaacg ccagccgtta
     5161 aggcaatggc atgtattcag tcaaaacgta cagaggaatt taaaaagatg ccggaatcca
     5221 ttcgaaacat gattactccg ccacgcaaca gtgctccacg cgtacaggat aatgaacctg
     5281 aagcctcccg aacgccagtg caggcagcag cacccgtggt ggatgaaaac agcatccgtg
     5341 cgcaggtact ggcagagcaa aaagcgcgtg taaacggtat taatgatctg tttgccatgt
     5401 ttggcgggcg ttatcagacg ctgcaggctc agtgtcttgc cgatcctgaa tgttcgctgg
     5461 agcaggcccg cgaaaagctg ttgaacgaga tggggcgcga gtccacgcca tccaataaaa
     5521 ataccccggc tcatatttat gccggtaacg gtaattttgt gggggacggg atccgccagg
     5581 cgctgatggc gcgtgccgga tttgaaaaaa ccgaacgtga taatgtctac aacgggatga
     5641 ccctgcgtga atatgcccgt atgtcactga ctgaacgggg tattggggtt tccggttata
     5701 acccgatgca gatggtcggt gcggcgttca cacacagtac gtctgacttc ggtaatattc
     5761 tgctggatgt tgcgaacaaa gccattctgc agggctggga agatgcccct gaaacctatg
     5821 aacagtggac gcggaaaggt cagttgtctg attttaaaat tgcccatcgt gtgggtatgg
     5881 ggggcttcag tgctctgcgt caggtgcgtg aaggggcgga atataaatac gtcaccaccg
     5941 gagataaaca ggccactatt gcactggcga cctatggcga gctgttcagt atcacccgtc
     6001 aggccattat caatgatgat ctgaatatgc tgaccgatgt cccgatgaag ctgggccgtg
     6061 cggcgaaatc cactattgcc gatctggttt atgccattct gacgtctaac ccgaaaatct
     6121 ccacagataa tgtaagtctg ttcgataaag cgaaacatgc aaacgtactg gagagcgctg
     6181 caatggacgt ggcatcgctg gataaagccc gccagttgat gcgcgttcag aaagaggggg
     6241 agcgtcatct gaatattcgt cctgcgttcg tactggtacc gacggcgatg gagtctgttg
     6301 ctaaccaggt cattcgctcc tcaagtgtca agggggctga cattaacgcc ggtattatta
     6361 acccggtgaa agattttgcg accgttattg cagagcctcg tcttgatgat aacagccaga
     6421 ccaccttcta cctggctgcg tcaaaaggct ccgatacgat tgaagtggct tatctcaacg
     6481 gtgtggatac gccatatatt gatcagatgg agggcttcag tgtggatggc gtgacaacga
     6541 aagtgcgtat tgacgccggt gtcgcgccag ttgatcaccg cggtctggtg aaatgtacgg
     6601 cgtaaacgtc gcagacaaca actctgatgg cccgtaaggg ctttttttgt acctgaaatc
     6661 agcccctgaa cggggctgtg cggagacagt tatggcaaag aattttgtag aagaaggaaa
     6721 aacggtggcg attgttgcca gtgcagccat cagcagcgga gatctggtgc aggtgggtga
     6781 tgtttttgcg gtggcgctga ccgatattcc acagggtgaa acaggcgacg gcatgaccga
     6841 aggtgtgttt atgctgccta agctgaaaac ggatgacatg aaaacgggta agaaggttta
     6901 tctgaagtcc ggaaaagttc agctgactaa cagcggctct gatccgctgg tcggggttgt
     6961 ctgggcagat gccggaacca gtgcagaaga agtgccggta aaactcaatg tctgatccct
     7021 tttcccggct ggcagcgcgt atggatgcga tcacggtcag aaagatggga aagacagcct
     7081 cgattaatga tgccgatatg actgtgatcc cgggagaaac actggcagag ctgaatgctc
     7141 tgtccggacc tgcggtatct ctggtggtgt tttcttcggg ataccgccca cggcgcgggg
     7201 atcgcgttgt ttatgacgga caacaatgga cggtcacacg gcatgaacgt tttaacggta
     7261 agccaatgat ctttattgag taaagaggtg tgggatgaag gggcttgaga ataccatccg
     7321 taatctgaac agccttgata cccgtatggt gccacaggcc agcgcatggg cgataaaccg
     7381 tgtggcacag aaagcggtct cggtcgccac ccggcaggtt gccgggaata ccgttgcggg
     7441 agataaccag gtgaaaggga tccccctgaa actggtacgt cagcgtgtcc gggtgtttaa
     7501 agccagtccg tcaggaaaaa tgacggccag gatccgcgtt aaccggggca atctgcccgc
     7561 tattaagctg gggacagccc gggtcagact ggcccggcgt ggtggaaaac tgcagtaccg
     7621 tggcagtgtg ctgaaggtgg gtaaatatct tttccgggat gcgtttattc agcaactggc
     7681 gaatggtcgt tggcatgtga tgcggcgtat tgatggcaaa aatcgttacc ccattgatgt
     7741 ggtgaaaatc ccgctgtccg gaccgctgac acaggcattt gaagatgccc gcgaccgcat
     7801 cattgctgcg gaaatgccga aacagctggg gtatgcactg aaacaacaac tgaggttatg
     7861 gctgacccga tgaaccgaca tacacaaatc cgccaggccg tactggcacg ccttcgggaa
     7921 cagtgtggag acagcgccac gttttttgac gggcttccgg catttattga tgcgcaggaa
     7981 ctgcctgccg tggcggtgtg gctgagtgat gctcagtaca ccggaaaaat gacggatgaa
     8041 gatgactggc aggctgttct gcatattgct gtcttcatcc gggcacaggc accggattca
     8101 gagctggata tgtggatgga gagcaccatt ttcccggccc tgaatgatat accggcactt
     8161 tccggactca tcgacaccct gatccctctc ggttttaact atcaacgtga taatgagatg
     8221 gccacctggg cgatggcgga aatcacgtac cagatcacgt acacgaatta aaggaggtgg
     8281 caatgaccac accaaatcca ctggcaaaaa cgaaaggtgc gggaacgacg ttctggatgt
     8341 acaccggcaa gggcgatgcg tttgcgaacc ctttatcgga cactgactgg ctgcgtcttg
     8401 cgatggtgaa ggatctgcaa cctggcgaaa tgaccgctga tgcagaagat gacacttatc
     8461 tcgatgatga agatgcagac tggaaaacga caacccaggg gcagaaatcc gtcggtgata
     8521 cttcggcgac gctggcctgg cgtccgggtg acagcgggca gaaaaaactg gttcagttgt
     8581 tcgactccgg tgaagtctgc gcgtttcgta tcaaatatcc caacggcact gttgatgttt
     8641 tccgtggctg gctgagctca ctgggtaaaa ccattgcctc aaaagacgtg atgacccgca
     8701 cagtgaaaat cagcggtgtg gggcgtccgt atctggcaga ggaaggcact gaaaccgtga
     8761 gcgttaccgg gctgacggtg gcaccggcat ctgccagtgt aaaagtggga gcaaccacca
     8821 cgctgacctt tacagtaaaa cctgacggag ccagtgacaa agcgatcagt gtgcattcga
     8881 cagatccaca gactgccacg gtgaccctga acgggcttgt ggccacggtg aaaggcgtga
     8941 agcagggcag tgtcagcatt gtgggcatga cttctgacgg cgattttgtg gcagtggctg
     9001 cggtggctgt cagcgcagca ggttaacagg acgatactca tcatttgccc cggttatccg
     9061 gggctttttt gcaggtggag aacatgatgt ttctgaaaca gggcacgttt aattatgaaa
     9121 agcagtccgt ggtgctcagt gagctgtccg ggctgcagag aattgaatat ctggcgtttg
     9181 ttcagcagcg aacggcaaag tttgatgccg aagagggaga actgccggag gctgaacgac
     9241 agattgcttt tctgcggatg gggatggata tcaatgcctg gctggtttcc cgctcactgt
     9301 ggaatgcgga acagtctcag gatgttgaga cgctttgcgc atccgttatt acaacatggt
     9361 cgtatgatgc cctgggtgcg ggggcggaga tggttctgtc gctgagcggt atgggggcca
     9421 ttgataatgc cggggatttg gagcatgagg tgctgacgcc ggaaaagtcc tgacgcggga
     9481 aatgcagttt gtcatgcggc ttgcccggga gttccggcgg gcagactggc ggcggatgct
     9541 gtcggaaatg tcggccactg agcttggtga atggggcgat tatttccgga tgcagagctt
     9601 cagtgatgtg tggatggatg cgcagtttgc ctcgctgaag gcattgatcg tgagaatggt
     9661 gtccggtagc agtgatgctg cggtggctga tttcagcctt ttaccggaag agaacgggat
     9721 accggagcga acggacgaag aactgatgca tcttggggaa ggtatttccg gaggtgtgcg
     9781 ttatggacca gatagccaac ctggtcattg atttggggat tgatgcggca gagtttaaaa
     9841 atgaaattcc ccgtatcaaa aaccttctga atggtgcagc cagcgatgca gaacggtctt
     9901 ctgcccgtat gcagcgtttt atggagcgtc agactcaggc cgcccggcag acaatgcagg
     9961 cggcttcttc ggctgcaaca gccgcatccg tccatgcgca gacggtggag aagagcgcac
    10021 aggctcatga acgcatggcc cgcgaggtgg agcaaacccg ccagcgtatg gaggcactga
    10081 gccagaaaat gcgcgaggaa caggcgcagg ccatggctct ggcggaggct caggataaag
    10141 cggctgccgc gttttatcgt cagattgaca gtgtgaaaca ggccagtgcg gggctgcagg
    10201 aattacagcg tattcagcag cagatccgac aggccagaaa cagtggcggg attggtcagc
    10261 aggattatct ggcgctgatt tctgaggtta cggcgaaaac ccgtgttctt acgcaggctg
    10321 aggcagaggc tacccgacag aaagtggcgt ttatccgtca gcttaaagag caggcaaccc
    10381 gccagaatct ttcttcttct gagttgcttc gtgctaaggc tgcccagctg ggggtaagca
    10441 gtgctgcaga agtgtatatc cgcaaaatgg agcaggcagg aaaagccacg cattcgctgg
    10501 gtctgaaaag tgcagcggcc cgccaggaga taggcgttct gataggtgaa ctggctcgcg
    10561 gcaatttagg tgcgctgagg ggatccggga taacgctggc taaccgtgcc ggatggatag
    10621 acacactgat gtcaccgaaa ggcatgatgc tgggcggggt tattggcggt attgccgcgg
    10681 ccgtctatgg tctgggtaaa gcctggtatg atggtcagaa ggagggggaa gaatttaacc
    10741 gccagttgtc gctgacgggg cattatgccg gagtcactgc cgggcagctg tggacgctca
    10801 gccgtgctat ttccgggaat ggtattacgc aacatgctgc agccggtgcg ctggctcagg
    10861 tggtggggag tggtgcattt cgtggaaacg atatcggtat ggtggcgaga gctgccgcac
    10921 agatggagcg atcggttggc cagtcggtca gcgataccat aaatcagttt aagcggctga
    10981 aggatgatcc tgtaaatgcc gcgaaggctc tggacaatga gctgcatttt cttactgcca
    11041 ctcagcttga gcagatacgt gtccttgggg atcagggacg gtccagtgat gcggcacgga
    11101 tagccatgtc tgcactggca gaggaaaccg gtcggcgtac tgcggatatt gataataacc
    11161 tcaatgcgct tggcagtacg ctgaagtatc tgtctgattt gtggagtcgt ttctgggatg
    11221 cggccatgaa tattggtcgt gaagactcgc tggatgaaca gatttccgct ttacaggaga
    11281 aagtgtcgcg ggcgaaaaga ctcccctgga cggcatcatc ttctcaggtt gagtacgatc
    11341 agcagcgtct taacgagctt caggagaaaa aacgccagaa ggatttgcag gatgcaaaag
    11401 agcaggcaga gcggaattat caggagcaac agaaacgccg taatgctgaa aatgctgcac
    11461 tgaaccggat gaatgaaacg gaagcagcac gacatcagcg tgaaattgcg cgtattaatg
    11521 ccatgcagta cgccgatcag gctgtcaggg atgcggcgat acaacgtgaa aatgaacgtt
    11581 acgagaaagc cctggcatcc ggtaagaaaa aaacacgcga accccgtaat gatgaggcca
    11641 cccggttatt gctgcagtac agtcagcaac aggcacaggt ggaaggacag attgctgctg
    11701 ccagacagtc agcaggcatt gccacggaaa ggatgacaga agcgcataaa cagcttctgg
    11761 ctctgcagca gcgcatcagc gacctggacg ggaaaaaact gacggcagat gaaaagagtg
    11821 tgctggcccg taaagatgaa ctgattcagg cactgacgct gctggatgta aaacagcagg
    11881 agcttcagaa acagacggca ctcaacgagc tgaagaaaaa aacaattcag ctgaccagtc
    11941 aactggctga agaagagcgc gctcagcgtc agcaacatga cctggatatc gccacggtgg
    12001 gtatgggtga tcagcagcgg cagcgatatc aggtacaact gagtcttcgc cagaaatacc
    12061 agcaacagct ggagcagttg aggcgggata gtgagcagaa agggacatat aacacggatg
    12121 actacagaaa ggccgagcag gcgctgacgg agagcctgaa ccgacaactg aatgagaatc
    12181 gccgttactg gcaacagctt gaagttgtgc agggtgactg gaaaaacgga gtcctgcgtg
    12241 cactccagaa tgtcactgag aatgcggata acacagccgg gacagtggaa cagttgttca
    12301 cgtctgcgtt cagtagcatg agtgactggc tggcgacatt ctgtactaca ggcaaactca
    12361 atttcaaatc cttcacctct tctgtgctgt cagatatgtc cagaatcatg gctcagatag
    12421 ctttaatgaa agcggtaaaa ggcattgctt ccgcgctgcc ttttgatttt gtagccaatg
    12481 ctgatggcgg tgtttatcag tcggctgatt tgagtcgcta cagtggcacg gtggttaacc
    12541 gtccgacgtt ttttgctttt gcaaaaggcg cgggtgtgat gggggaagcg ggacctgaag
    12601 ccattctgcc actgcgtcgt gatgctgacg gtaagctggg ggttgtggcg gatattggtg
    12661 gttcaggtat ggcgatgttt gccccgcagt acaacataga gatcaataac gatggcacga
    12721 acgggcagat aggtccggct gctctgaagg tggtttatga cctcgggaaa aaagcagcag
    12781 cggactttat gcaacagcag gcccgtgatg gtggtcggtt aagtggagca tatcggtaat
    12841 ggagacgttt cactggaaag tgcgcccgga tatgaatgtg gtatcagagc cgaaagtggt
    12901 gacagtgaag ctgggcgatg gttatgaaca gcgtcgtgcg gcgggactga ataaccagtt
    12961 gtcgacttac agcgtgacga tacgtgttcg taaatgtgaa cacccatctt taaaagcctt
    13021 tctggaacgg cacggtggcg tccgcgcatt tcagtggacg ccaccttatg actggaagcc
    13081 gatcagggtg gtttgtcgta aatggtcggc gagcgtaggg gcgctgtggg taaccataac
    13141 ggcagatttt gaacaggtcg tggcatagga ggctctgatg caggatattc cacaggaaac
    13201 acatcatgag acgacacgcc tcactcagtc agcccaggtg gtgctctggg aaatcgatct
    13261 gacagaggtc ggtggtgaac gttatttttt ctgtaatgag cagaacgaaa aaggtgagcc
    13321 ggtcacctgg caggggcggc agtatcaggc ataccccatt caggggacgg gatttgaact
    13381 gaacggcaag ggcagtgctg cccgtccgac actgacggtt tctaacctgc acggcatggt
    13441 caccgggatg gcggaagacc tgcagagtct ggtcggcgga acggtggtca ggcgtaaggt
    13501 ttacgcccgt tttctggatg cggtgaactt cgtcaacgga aacagcgacg ccgatccaga
    13561 gcaggaggtg atcagccgct ggcgcatcga gcagtgcagc gaactgagtg cggtcagtgc
    13621 ctcctttgtg ttgtccacac cgacggaaac gga
//
LOCUS       DAPGUL010000119        13620 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.121, whole genome shotgun sequence.
ACCESSION   DAPGUL010000119 DAPGUL010000000
VERSION     DAPGUL010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13620
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.121"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            27..1793
                     /gene="adeD"
                     /locus_tag="RHX21_003758"
     CDS             27..1793
                     /gene="adeD"
                     /locus_tag="RHX21_003758"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HDV1988882.1"
                     /translation="MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLIN
                     GGEISGPIVIKGRYIAGVGAEYADAPALQRIDARGATAVPGFIDAHLHIESSMMTPVT
                     FETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCD
                     VNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGL
                     GGKELNAYITAGIENCHESYQLEEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNS
                     PQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVASWSTARHFGLNHLGL
                     LAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAEESARLAQSAPPYGNTIARQP
                     VSASDFALQFTPGKRYRVIDVIHNELITHSHSSVYSENGFDRDDVSFIAVLERYGQRL
                     APACGLLGGFGLNEGALAATVSHDSHNIVVIGRSAEEMALAVNQVIQDGGGLCVVRNG
                     QVQSHLPLPIAGLMSTDTAQLLAEQIDALKAAARECGPLPDEPFIQMAFLSLPVIPAL
                     KLTSQGLFDGEKFAFTTLEVTE"
     gene            complement(1838..3229)
                     /gene="uhpT"
                     /locus_tag="RHX21_003759"
     CDS             complement(1838..3229)
                     /gene="uhpT"
                     /locus_tag="RHX21_003759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose-6-phosphate:phosphate antiporter"
                     /protein_id="HDV1988883.1"
                     /translation="MLAFLNQVRKPTLDLPLEVRRKMWFKPFMQSYLVVFIGYLTMYL
                     IRKNFNIAQNDMISTYGLSMTQLGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFML
                     ILSAICMLGFSASMGSGSVSLFLMIAFYALSGFFQSTGGSCSYSTITKWTPRRKRGTF
                     LGFWNISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRYGSDSPE
                     SYGLGKAEELFGEEISEEDKETESTDMTKWQIFVEYVLKNKVIWLLCFANIFLYVVRI
                     GIDQWSTVYAFQELKLSKAVAIQGFTLFEAGALVGTLLWGWLSDLANGRRGLVACIAL
                     ALIIATLGVYQHASNEYIYLASLFALGFLVFGPQLLIGVAAVGFVPKKAIGAADGIKG
                     TFAYLIGDSFAKLGLGMIADGTPVFGLTGWAGTFAALDIAAIGCICLMAIVAVMEERK
                     IRREKKIQQLTVA"
     gene            complement(3367..4686)
                     /gene="uhpC"
                     /locus_tag="RHX21_003760"
     CDS             complement(3367..4686)
                     /gene="uhpC"
                     /locus_tag="RHX21_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709527.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter family glucose-6-phosphate
                     receptor UhpC"
                     /protein_id="HDV1988884.1"
                     /translation="MLPFLKAPADAPLMTDKYEIDARYRYWRRHILLTIWLGYALFYF
                     TRKSFNAAVPEILANGVLSRSDIGLLATLFYITYGVSKFVSGIVSDRSNARYFMGIGL
                     IATGIMNILFGFSTSLWAFAVLWVLNAFFQGWGSPVCARLLTAWYSRTERGGWWALWN
                     TAHNVGGALIPIVMAASALHYGWRAGMMIAGCMAIVVGIFLCWRLRDRPQALGLPAVG
                     EWRHDALEIAQQQEGAGLTRKEILTKYVLLNPYIWLLSFCYVLVYVVRAAINDWGNLY
                     MSETLGVDLVTANTAVTMFELGGFIGALVAGWGSDKLFNGNRGPMNLIFAAGILLSVG
                     SLWLMPFASYVMQATCFFTIGFFVFGPQMLIGMAAAECSHKEAAGAATGFVGLFAYLG
                     ASLAGWPLAKVLDTWHWSGFFVVISIAAGISALLLLPFLNAQAPREA"
     gene            complement(4696..6198)
                     /gene="uhpB"
                     /locus_tag="RHX21_003761"
     CDS             complement(4696..6198)
                     /gene="uhpB"
                     /locus_tag="RHX21_003761"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418124.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction histidine-protein
                     kinase/phosphatase UhpB"
                     /protein_id="HDV1988885.1"
                     /translation="MKTLFSRLITVIACFFIFSAAWFCLWSISLHLVERPDMAVLLFP
                     FGLRLGLMLQCPRGYWPVLLGAEWLLIYWLTQAVGLTHFPLLMIGSLLTLLPVALISR
                     YRHQRDWRTLLLQGAALTAAALLQSLPWLWHGKESWNALLLTLTGGLTLAPICLVFWH
                     YLANNTWLPLGPSLVSQPINWRGRHLVWYLLLFVISLWLQLGLPDELSRFTPFCLALP
                     IIALAWHYGWQGALIATLMNAIALIASQTWRDHPVDLLLSLLVQSLTGLLLGAGIQRL
                     RELNQSLQKELARNQHLAERLLETEESVRRDVARELHDDIGQTITAIRTQAGIVQRLA
                     ADNASVKQSGQLIEQLSLGVYDAVRRLLGRLRPRQLDDLTLEQAIRSLMREMELEGRG
                     IVSHLEWRIDESALSENQRVTLFRVCQEGLNNIVKHADASAVTLQGWQQDERLMLVIE
                     DDGSGLPPGSGQQGFGLTGMRERVTALGGTLHISCLHGTRVSVSLPQRYV"
     gene            complement(6198..6788)
                     /gene="uhpA"
                     /locus_tag="RHX21_003762"
     CDS             complement(6198..6788)
                     /gene="uhpA"
                     /locus_tag="RHX21_003762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator UhpA"
                     /protein_id="HDV1988886.1"
                     /translation="MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLP
                     GRGVQVCICDISMPDISGLELLSQLPKGMATIMLSVHDSPALVEQALNAGARGFLSKR
                     CSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
                     ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW"
     gene            complement(6863..7153)
                     /gene="ilvN"
                     /locus_tag="RHX21_003763"
     CDS             complement(6863..7153)
                     /gene="ilvN"
                     /locus_tag="RHX21_003763"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HDV1988887.1"
                     /translation="MQNTTHDNVILELTVRNHPGVMTHVCGLFARRAFNVEGILCLPI
                     QDSDKSHIWLLVNDDQRLEQMISQIDKLEDVVKVQRNQSDPTMFNKIAVFFQ"
     gene            complement(7157..8845)
                     /gene="ilvB"
                     /locus_tag="RHX21_003764"
     CDS             complement(7157..8845)
                     /gene="ilvB"
                     /locus_tag="RHX21_003764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HDV1988888.1"
                     /translation="MASSGTTSTRKRFTGAEFIVHFLEQQGIKIVTGIPGGSILPVYD
                     ALSQSTQIRHILARHEQGAGFIAQGMARTDGKPAVCMACSGPGATNLVTAIADARLDS
                     IPLICITGQVPASMIGTDAFQEVDTYGISIPITKHNYLVRHIEELPQVMSDAFRIAQS
                     GRPGPVWIDIPKDVQTAVFEIEAQPAVAEKAAAPAFSEESIRDAATMINAAKRPVLYL
                     GGGVINAPARVRELAEKAQLPTTMTLMALGMLPKAHPLSLGMLGMHGVRSTNYILQEA
                     DLLIVLGARFDDRAIGKTEQFCPNAKIIHVDIDRAELGKIKQPHVAIQADVDDVLAQL
                     IPLVEAQPRAEWHQLVADLQREFPCPIPKACDPLSHYGLINAVAACVDDNAIITTDVG
                     QHQMWTAQAYPLNRPRQWLTSGGLGTMGFGLPAAIGAALANPDRKVLCFSGDGSLMMN
                     IQEMATASENQLDVKIILMNNEALGLVHQQQSLFYEQGVFAATYPGKINFMQIAAGFG
                     LETCDLNNEADPQAALQEIINRPGPALIHVRIDAEEKVYPMVPPGAANTEMVGE"
     gene            complement(8951..9049)
                     /gene="ivbL"
                     /locus_tag="RHX21_003765"
     CDS             complement(8951..9049)
                     /gene="ivbL"
                     /locus_tag="RHX21_003765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ilvB operon leader peptide IvbL"
                     /protein_id="HDV1988889.1"
                     /translation="MTTSMFNAKLLPTAPSAAVVVVRVVVVVGNAP"
     gene            9614..9703
                     /gene="tisB"
                     /locus_tag="RHX21_003766"
     CDS             9614..9703
                     /gene="tisB"
                     /locus_tag="RHX21_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin TisB"
                     /protein_id="HDV1988890.1"
                     /translation="MSLVDIAILILKLIVAALQLLDAVLKYLK"
     gene            9983..11167
                     /gene="emrD"
                     /locus_tag="RHX21_003767"
     CDS             9983..11167
                     /gene="emrD"
                     /locus_tag="RHX21_003767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418129.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EmrD"
                     /protein_id="HDV1988891.1"
                     /translation="MKRQRNVNLLLMLVLLVAVGQMAQTIYIPAIADMARDLNVREGA
                     VQSVMGAYLLTYGVSQLFYGPISDRVGRRPVILVGMSIFMLATLVAVTTSSLTVLIAA
                     SAMQGMGTGVGGVMARTLPRDLYERTQLRHANSLLNMGILVSPLLAPLIGGLLDTMWN
                     WRACYLFLLVLCAGVTFSMARWMPETRPVDAPRTRLLTSYKTLFGNSGFNCYLLMLIG
                     GLAGIAAFEACSGVLMGAVLGLSSMTVSILFILPIPAAFFGAWFAGRPNKRFSTLMWQ
                     SVICCLLAGLLMWIPDWFGVMNVWTLLVPAALFFFGAGMLFPLATSGAMEPFPFLAGT
                     AGALVGGLQNIGSGVLASLSAMLPQTGQGSLGLLMTLMGLLIVLCWLPLATRMSHQGQ
                     PV"
     gene            complement(11175..11672)
                     /locus_tag="RHX21_003768"
     CDS             complement(11175..11672)
                     /locus_tag="RHX21_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HDV1988892.1"
                     /translation="MTGSQVIDAEEDRHKLVVEYKDALQPADFYHNFKQRGIRSVQLI
                     PYLEFDDRGDLTAASVTAELWGKFLIALFECWVRADISRISIELFDATLQKWCGSENP
                     QPRRDCQACDWHRLCPHARQETPDSVLCAGYQAFYSYSAPHMRVMRDLIKQHRSPMEL
                     MTMLR"
     gene            complement(11669..12031)
                     /locus_tag="RHX21_003769"
     CDS             complement(11669..12031)
                     /locus_tag="RHX21_003769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF202 domain-containing protein"
                     /protein_id="HDV1988893.1"
                     /translation="MPDSRKARRIADPGLQPERTSLAWFRTMLGYGALMALAIKHNWH
                     QAGMLFWISIGILAIVALILWHYTRNRNLMDVTNSDFSQFHVVRDKFLISLAVLSLAI
                     LFAVTHIHQLIVFIERVA"
     gene            complement(12021..12368)
                     /locus_tag="RHX21_003770"
     CDS             complement(12021..12368)
                     /locus_tag="RHX21_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidH family protein"
                     /protein_id="HDV1988894.1"
                     /translation="MNISRLGEAPDYRFSLANERTFLAWIRTALGFLAAGVGLDQLAP
                     DFATPVIRELLALLLCLFSGGLAMYGYLRWLRNEKAMRLKEDLPYTNSLLIISLILMV
                     VAVIVMGLVLYAG"
     gene            complement(12539..>13620)
                     /locus_tag="RHX21_003771"
     CDS             complement(12539..>13620)
                     /locus_tag="RHX21_003771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001458895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDV1988895.1"
                     /translation="EAGNKYIPYGKMASWLVEWKNATETQWLKDSPSQPLQQSLKGLE
                     RAYKNFFQKRAAFPRFKKRGQNDAFRYPQGVKLDQENSRIFLPKLGWMRYRNSRQVTG
                     VVKNVTVSQSCGKWYISIQTESEVSTPVHPSASMIGLDAGVAKLATLSDGTVFEPVNS
                     FQKNQKTLERLQRQLSRKVKFSNNWQKQKRKIQRLHSCIANIRRDYLHKVTTTVSKNH
                     AMIVIEDLKVSNMSKSAAGTVSLPGRNVRAKSGLNRSILDQGWYEIRRQLAYKQLWRG
                     GQVLAVPPAYTSQRCVCCGHTAKENRLSQSKFRCQVCGYTANADVNGARNILAAGHAV
                     LACGEMVQSGRSLKQEPTEMIQATA"
BASE COUNT         3195 a         3812 c         3562 g         3051 t
ORIGIN      
        1 attgataaaa tcaaaatgag aaaaatatga ataattctat taaccataaa tttcatcaca
       61 ttagccgggc tgaataccag gaattgttag ccgtttcccg tggcgacgct gttgccgatt
      121 atattattga taatgtctct attctcgacc tgatcaatgg cggagaaatt tccggcccaa
      181 ttgtgattaa aggacgttac attgccggtg ttggcgcaga atacgctgat gctccggctt
      241 tgcagcggat tgatgctcgc ggcgcaacgg cggtgccagg gtttattgat gctcacctgc
      301 atattgaatc cagcatgatg acgccggtca cttttgaaac cgctaccctg ccgcgcggcc
      361 tgacgaccgt tatttgcgac cctcatgaaa tcgtcaacgt gatgggagaa gccggattcg
      421 cctggtttgc ccgctgtgcc gaacaggcaa ggcaaaacca gtacttacag gtcagctctt
      481 gcgtacccgc cctggaaggc tgcgatgtta acggtgccag ttttaccctt gaacagatgc
      541 tcgcctggcg ggaccatccg caggttaccg gccttgcaga aatgatggac taccctggcg
      601 taattagcgg gcagaatgcg ctgctcgata aactggatgc atttcgccac ctgacgctgg
      661 acggtcactg cccgggtttg ggtggtaaag aacttaacgc ctatattact gcgggtattg
      721 aaaactgcca cgaaagttat cagctggaag aaggacgccg gaaattacaa ctcggcatgt
      781 cgttgatgat ccgcgaaggg tccgctgccc gcaatctcaa cgcgctggca ccgttgatca
      841 acgaatttaa cagcccgcaa tgcatgctct gtaccgatga ccgtaacccg tgggagatcg
      901 cccatgaagg acacatcgat gccttaattc gccgcctgat cgaacaacac aatgtgccgc
      961 tgcatgtggc atatcgcgtc gccagctggt cgacggcgcg ccactttggt ctgaatcacc
     1021 tcggcttact ggcacccggc aagcaggccg atatcgtcct gttgagcgat gcgcgtaagg
     1081 tcacggtgca gcaggtactg gtgaaaggcg agccgattga tgcgcaaacc ttacaggcgg
     1141 aagagtcggc gagactggca caatccgctc cgccatatgg caacaccatt gcccgccagc
     1201 cagtttccgc cagcgacttt gccctgcaat ttacgcccgg aaaacgctat cgggtcattg
     1261 acgtcatcca taacgaattg attacgcact cccactccag cgtctacagc gaaaatggtt
     1321 ttgatcgcga tgatgtgagc tttattgccg tacttgagcg ttacgggcaa cggctggctc
     1381 cggcttgtgg tttgcttggc ggctttggac tgaatgaagg tgcgctggct gcgacggtca
     1441 gccatgacag ccataatatt gtggtgatcg gtcgcagtgc cgaagagatg gcgctggcgg
     1501 tcaatcaggt gattcaggat ggcggcgggc tgtgcgtggt acgtaacggc caggtccaaa
     1561 gtcatctgcc gttgcccatt gccggcctga tgagcaccga cacggcgcag ttgctggcgg
     1621 aacaaattga cgccttgaaa gccgccgccc gtgaatgcgg tccgttaccc gatgagccgt
     1681 ttattcagat ggcgtttctt tctctgccag tgatccccgc gctaaaacta accagtcagg
     1741 ggctatttga tggcgagaag tttgccttca ctacgctgga agtcacggaa taataaaaaa
     1801 gcccggcgtc atgccgggca aaagtcacca gttacgttta tgccactgtc aactgctgaa
     1861 tttttttctc gcggcggatt ttgcgttctt ccatcaccgc cactatcgcc atcaggcaga
     1921 tacaaccaat cgcggcgata tcaagtgcgg cgaaggtgcc tgcccagccg gtaaggccga
     1981 ataccggcgt cccatcggca atcattccca gacctaactt ggcaaagctg tcaccaatca
     2041 ggtaagcaaa ggtgccttta ataccatcgg cagcgccaat cgctttttta ggtacaaagc
     2101 caacagcagc cacaccaatc aacaattgcg ggccaaagac caggaaaccc aacgcaaaga
     2161 gagaagccag atagatatat tcgttgctgg catgttgata cacaccgagc gtggcgataa
     2221 tcagcgccag cgcgatgcag gccaccaggc cacggcgacc gttcgccagg tcagagagcc
     2281 agccccacag cagcgtaccg accagcgcac cagcttcaaa cagcgtaaag ccctgaatcg
     2341 ccaccgcttt agagagtttc agttcctgga acgcgtacac ggttgaccac tggtcgatac
     2401 caatacgcac cacatagagg aaaatgttgg cgaagcacag cagccagatc actttgtttt
     2461 tcagcacata ctcaacaaag atctgccact tggtcatatc ggtagattct gtctctttgt
     2521 cctcttcgct gatctcctcg ccgaacagct cttccgcttt gccgaggcca taagattccg
     2581 gggagtcgct gccgtaacgc aggccgataa aaccgacaat caacgcgata atcgacggga
     2641 agataaacat gccgatcacg tggccgtcga acaggtaatt tgcgccgaac agcgccacac
     2701 cagccgcacc cgcgccgcca aggttatggg aaatgttcca gaaaccgagg aaggtcccgc
     2761 gcttacgacg cggtgtccat ttggtgatgg tggagtaact gcacgaaccg ccggtactct
     2821 ggaaaaagcc gcttaaggcg tagaaggcaa tcatcaggaa caggctaacc gagccgctgc
     2881 ccatactggc actgaagccc agcatacaaa tggcagacag gatcagcatg aacggcagga
     2941 attgtttggt gtttttgccg tcggcgtagt aggaaaccag cgttttaccc acgccataag
     3001 tgatggagaa acccaggccg atcatcccca gctgcgtcat gctcaacccg taggtcgaga
     3061 tcatgtcgtt ctgcgcgatg ttaaagttct tgcgaatcag gtacatcgtc aggtagccga
     3121 taaagaccac caggtaggat tgcatgaacg gtttgaacca cattttgcgc cgcacttcga
     3181 gcggaaggtc cagggtcggc ttgcgaacct ggtttaagaa agccagcatg ggttactcct
     3241 gaaatgaata cctgcgtgag gcatgcattg taaaaatcag cagcaaatca ggcctgagat
     3301 agcgtccagg caaaacctgg aaaatttctt agttttgccg gatatgaagt gaaaaggtga
     3361 gatgcatcac gcttcgcgcg gtgcctgggc gttcaaaaag ggcagtaaca gcagtgcgga
     3421 aatcccggcg gcgatagaga taaccacaaa aaatccgctc cagtgccagg tatcgagtac
     3481 tttcgccagc ggccaaccag caagcgacgc ccccagataa gcaaacaagc cgacaaaccc
     3541 cgtcgccgcc cctgccgcct ctttgtggga acactctgcc gccgccatgc cgattaacat
     3601 ctgcgggcca aagacaaaaa aaccaatggt gaagaagcag gttgcctgca tcacgtagct
     3661 ggcaaatggc atcagccaca gcgagccgac tgaaagcaaa attccggcgg cgaaaatcaa
     3721 attcatcggc ccacggttgc cgttaaacaa tttgtccgag ccccaaccgg ctaccagcgc
     3781 accgataaat ccgcccagtt caaacatcgt cactgccgta ttcgccgtga ccagatcgac
     3841 gcccagtgtc tcggacatat acaaattgcc ccagtcgttg atcgccgccc ggaccacata
     3901 gaccagcaca tagcaaaacg aaagcagcca gatatacgga ttcagcaaca catatttggt
     3961 caggatctct ttacgcgtca accctgcccc ttcttgttgt tgagcaattt ccagcgcgtc
     4021 gtgccgccat tcaccgaccg ccggtaaacc taacgcctgc gggcgatcgc gtagccgcca
     4081 gcagagaaaa atccccacga ctatcgccat acaaccagca atcatcatcc cggcacgcca
     4141 gccgtaatgc agcgcgctcg ctgccatcac aatgggaatg agtgcgccgc cgacgttatg
     4201 cgccgtgttc cataatgccc accaaccgcc gcgctcggta cgtgaatacc aggccgttaa
     4261 cagacgcgca cacaccggtg aaccccagcc ctggaaaaag gcgttcagca cccagagcac
     4321 ggcaaacgcc catagcgacg tcgagaagcc aaacagaatg ttcatgatgc ccgtggcgat
     4381 aagccctatc cccataaaat aacgggcatt tgagcgatcg ctgacaatgc cggagacaaa
     4441 cttcgacacg ccgtaagtaa tgtaaaacag ggtcgctaac aggccgatat cgctacggct
     4501 gagcacgccg ttagcaagga tttctggtac cgcggcgtta aaacttttcc gcgtgaagta
     4561 aaacagcgcg taacccagcc agatggtcag cagaatatgc cgacgccagt agcgatagcg
     4621 ggcatcaatt tcatatttat cagtcattaa tggcgcatcg gcaggcgctt tcagaaacgg
     4681 caacatcatc aaaccttaga catagcgttg aggtagagaa acgctgacac gcgtgccgtg
     4741 cagacaggaa atgtgtaatg tgccacccag cgccgttacg cgctcgcgca ttccggtgag
     4801 gccaaaacct tgttgcccgg aacccggcgg caaaccgctg ccatcgtctt caataaccag
     4861 catcaaccgt tcatcctgct gccagccttg cagggtgacc gcgctggcat cagcatgttt
     4921 cacaatgttg ttcagccctt cctggcagac acgaaacagc gtcacgcgct ggttttcgct
     4981 taacgctgat tcatcgattc gccattcgag atggctgaca ataccgcgcc cttccagctc
     5041 catttcccgc atcagtgagc ggatggcctg ctccagggtg agatcatcca actggcgcgg
     5101 acgtaaccga cccaacaaac ggcgcaccgc gtcgtaaacg cccagcgata gttgttcgat
     5161 gagctgcccg ctctgcttca cgctggcgtt atctgccgcc agccgctgaa caatgcccgc
     5221 ctgagtacga atggctgtga tggtctgacc gatatcatca tgcagctcac gcgccacatc
     5281 acggcgcacg ctctcttcgg tttccagcaa ccgttcagcc agatgctgat tgcgcgccag
     5341 ttccttttgc agcgactggt taagttcacg caaccgctgg atgccagcgc caagcaacaa
     5401 ccctgtcaga ctttgcacca gcagcgagag caataaatcc accggatgat cgcgccaggt
     5461 ttgactggcg atcagcgcga tggcgttcat caacgtcgca atcagcgccc cttgccaacc
     5521 atagtgccag gccagcgcga taatcggcag cgccagacaa aatggcgtaa agcgcgacag
     5581 ttcgtccggc aatcccaact ggagccagag actgataaca aacagcagca agtaccagac
     5641 cagatgtcgc ccgcgccagt tgatcggctg agaaaccagt gacgggccga gcggcagcca
     5701 ggtgttattg gcgagatagt gccagaacac cagacatatc ggggccagcg tcaggccgcc
     5761 agttaaagtc agcaacagcg cattccacga ctctttgccg tgccaaagcc agggcagcga
     5821 ctgcaacaac gccgccgccg ttaacgccgc accctgtaac agcaaggtgc gccagtcacg
     5881 ctgatggcga tagcgcgaga tcagcgccac gggcagtaac gtcagtaaac taccgatcat
     5941 caataacgga aaatgggtta aaccgaccgc ctgcgttagc cagtaaatca gcagccactc
     6001 cgcgcccagc agcaccggcc agtatccgcg cgggcattgc agcattagcc ccagacgcag
     6061 accaaacgga aataacagca ccgccatatc agggcgctca accaggtgca ggctgatact
     6121 ccacaggcaa aaccatgcgg cagagaagat aaaaaagcag gcaataacgg taattaagcg
     6181 ggagaacaac gtcttcatca ccagccatca aacatgcggc gcgccagctc tacgtcgtta
     6241 ctgacaccca gtttttccat caggttggcg cgatggacgt gcaccgtttt cggcgacaag
     6301 cccagttcgg cagcaatctc tttcaccgcc attccttgcg ccagtttttc cgccacctgc
     6361 cgttcgcgtt tggttagcgg gtcctgacga ccggatgcca gtttaatggc aatatccggc
     6421 gtcagataac agccgcccgt ggcaaccgta tgcaccgccg caatcagttc gtcagggcta
     6481 cagcgtttgg agagaaagcc gcgtgccccc gcgttaagcg cctgctcaac cagcgccgga
     6541 ctgtcatgaa cagagagcat tattgtcgcc atacctttcg gcagctggct tagcagttcc
     6601 agaccggaga tatcgggcat ggagatatcg caaatacaca cctgcacacc gcgccccggc
     6661 agccccgcca gcgcctcgcg ccccgaacca aactcggcaa ctacctgcaa atcaggttcc
     6721 agccccagca gctgcgcaaa gccggagcgg acgatgaggt gatcgtctat aagggcaacg
     6781 gtgatcatgg tcttgtcctg gcgggtaaaa aaaaacgcgc ttaccttaac gataagcgcg
     6841 atgttgttca agccttgagc ggttactgaa aaaacaccgc gatcttgtta aacatcgtcg
     6901 gatcggactg attacgctgc actttcacga catcttccag cttatcgatt tggcttatca
     6961 tctgctccag acgctggtcg tcattgacca gtagccagat atggcttttg tcgctgtcct
     7021 gaatcggcag acaaagaatg ccttcaacgt taaaagcgcg gcgggcaaaa aggccacaaa
     7081 cgtgggtcat tacgcccgga tggttgcgaa cggtgagctc cagaattacg ttgtcatgag
     7141 ttgtgttttg catggcttat tcccccacca tttcagtatt cgccgcacct ggcggcacca
     7201 tcgggtaaac tttttcttcg gcatcaatgc gcacatggat cagcgccggg ccagggcgat
     7261 tgatgatttc ctgcaatgca gcctgcggat cggcttcgtt attcaaatca caggtttcga
     7321 ggccgaatcc ggcggcaatc tgcataaagt tgattttgcc cggataggtg gcggcaaaaa
     7381 cgccttgctc gtagaacaga ctctgttgct gatgcaccag ccccagcgct tcgttgttca
     7441 tcagaatgat tttgacatcc agctgatttt cactggcggt cgccatctcc tgaatattca
     7501 tcatcaggct gccgtcgccg gagaaacaca acactttgcg atccgggttc gccagcgccg
     7561 cgccaatcgc cgcaggcagg ccaaaaccca tcgtgcccag cccaccggag gtcagccact
     7621 ggcgtgggcg attgagcgga taagcttgcg cggtccacat ctgatgctgc cccacatcgg
     7681 tggtgataat cgcattgtca tcgacacagg cggcaacggc gttgatcagg ccgtaatggc
     7741 ttaatggatc gcacgctttc gggattggac acggaaactc acgctgcaaa tccgctacca
     7801 actggtgcca ctctgcacgc ggttgcgctt ccaccagcgg gatcaactgc gccagcacgt
     7861 catcaacatc cgcctgaatc gccacatgcg gctgcttgat tttacccagc tctgcacggt
     7921 cgatatcgac atgaatgatt ttggcattcg gacagaactg ctcggttttg ccaatcgccc
     7981 ggtcatcaaa acgcgcaccg agcacaatca gtaaatccgc ctcctgcaag atatagttag
     8041 tgctgcgcac gccgtgcatc cccagcatac ccagcgacaa cggatgcgct tttggcagca
     8101 tgcccagcgc cattaaagtc atggtggtag gcagttgcgc tttctccgcc agttcacgca
     8161 cccgcgcagg cgcattgatc acaccaccac ccagataaag caccgggcgt ttggcagcgt
     8221 taatcattgt agctgcgtca cgaatgcttt cttcgctaaa ggcgggtgca gcggcttttt
     8281 ctgccaccgc gggctgagct tcaatctcaa aaaccgccgt ttgcacatcc ttaggaatgt
     8341 ctatccacac cgggcctggg cggcctgatt gcgcaatgcg gaaggcatcg ctcatgacct
     8401 gcgggagttc ttcgatatgt ctgaccagat agttgtgttt ggtgatgggg atagagatgc
     8461 cgtaggtgtc gacttcctgg aaggcgtcgg tgccgatcat cgaggcggga acctgaccag
     8521 tgatgcaaat cagcgggatg gagtccagcc gcgcatcggc aatggcggtc accaggttag
     8581 tcgcacccgg tccgctacag gccatacaga ccgccggttt accgtcggtg cgcgccattc
     8641 cctgagcgat aaatcccgcg ccctgttcat ggcgagccag aatatggcgg atttgcgtac
     8701 tttggcttaa ggcatcgtaa acaggcagga tagaaccgcc cggaatgccc gtcacaatct
     8761 taatgccctg ctgttccagg aaatgaacga taaattctgc gccggtaaag cgcttacgcg
     8821 tcgatgttgt gcccgaactt gccatgctcc agtccttttc ttctgggccg actttccggg
     8881 aggtgcttaa acgaaaaacc ccgcccggtt tgcgccggcg gggttttgga atcgtgtgtt
     8941 gttccagtcc ctacggcgca ttgccgacga ccaccaccac acgcacgacg accactgcgg
     9001 cggatggcgc agttggtagt agttttgcgt tgaacatgga agtagtcatt ggggaccttg
     9061 ttggttttgt gtttaacaat atttatacaa gcacagcttt acaggggaga caatggaaaa
     9121 tttttcagca agggaaaatt gaggggttga tcacgttttg tactgaattg cagataacaa
     9181 aaaaccccgc cggagcgagg tttcgtcagt cgcctgcggc tggtaaccgc aaagcacact
     9241 gtattatgtc aacactgaaa gtatacgtgt tccgcgcaga acgcgcaatt tcggcacgaa
     9301 ttttgacgta tttagtgcat agttgagtat cgatcacagt ttgcgttttg tccaaatatt
     9361 actgtttatt tatacagtaa acttctataa tatcactgta cgcaatgtgt tatgcggggg
     9421 ccgcatcgtt acccggcgca ctaagtcctg gctgaaacgg gtggtgccgt cagcgcctta
     9481 accccgcgtg agcacactgt gttatgtcaa caagcacaac gtttctcctt gagataccgc
     9541 gtgcacaaca gctggcaaca ggcagcggaa aggtacgtca gctggcagtg ctcctgaacc
     9601 acaggagacg cgtatgagcc tggtggatat cgccattctt atcctcaaac tcattgttgc
     9661 agcactgcaa ctgcttgatg ctgttctgaa atacctgaag taattcagat tcaagtcgca
     9721 ccaaagggga gcgggaaacc gctccccttt tatatttagc gtgcgggttg gtgtcggatg
     9781 cgatgctgac gcatcttatc cgccctacca tctctcccgg caacatttat tgccgctttt
     9841 gtttacatat tctgccgcta aacaattccc cattcctggc gtatatctgg ctaacattca
     9901 tcaatgtgat agattcctct cccgcattta tgggaatgcg tagtgactta ttctaattat
     9961 ttttataaaa gcatccgtga taatgaaaag gcaaagaaac gtcaatttgt tattgatgtt
    10021 ggtattactc gtggccgtcg gtcagatggc gcaaaccatt tatattccag ctattgccga
    10081 tatggcgcgc gatctcaacg tccgtgaagg ggcggtgcag agcgtaatgg gcgcttatct
    10141 gctgacttac ggtgtctcac agctgtttta tggcccgatt tccgaccgcg tgggccgccg
    10201 accggtgatc ctcgtcggaa tgtccatttt tatgctggca acgctggtcg cggtcacgac
    10261 ctccagtttg acggtgttga ttgccgccag cgcgatgcag gggatgggca ccggcgttgg
    10321 cggcgtaatg gcgcgtactt tgccgcgaga tttatatgaa cggacacagt tgcgccatgc
    10381 taacagcctg ttaaacatgg ggattctcgt cagtccgttg ctcgcaccgc taatcggcgg
    10441 tctgctggat acgatgtgga actggcgcgc ctgttatctc tttttgttgg ttctttgtgc
    10501 tggtgtgacc ttcagtatgg cccgctggat gccggaaacg cgtccggtcg atgcaccgcg
    10561 cacgcgcctg cttaccagtt ataaaacgct tttcggtaac agcggtttta actgttattt
    10621 gctgatgctg attggcggtc tggccgggat tgccgccttt gaagcctgct ccggcgtgct
    10681 gatgggcgcg gtgttagggc tgagcagtat gacggtcagt attttgttta ttctgccgat
    10741 tccggcagcg ttttttggcg catggtttgc cggacgtccc aataaacgct tctccacgtt
    10801 aatgtggcag tcggttatct gctgcctgct ggctggcttg ctgatgtgga tccccgactg
    10861 gtttggcgtg atgaatgtct ggacgctgct cgttcccgcc gcgctgttct ttttcggtgc
    10921 cgggatgctg tttccgctgg cgaccagcgg cgcgatggag ccgttcccct tcctggcggg
    10981 cacggctggc gcgctggtcg gcggtctgca aaacattggt tccggcgtgc tggcgtcgct
    11041 ctctgcgatg ttgccgcaaa ccggtcaggg tagcctgggg ttattgatga ccttaatggg
    11101 attgttgatc gtgctgtgct ggctgccgct ggcgacgcgg atgtcgcatc aggggcagcc
    11161 cgtttaagcg cacgtcaccg cagcatcgtc atcagctcca tgggagaacg atgctgcttt
    11221 atcagatcac gcatcacccg catatgcggt gcggagtaag aataaaacgc ctgatagccc
    11281 gcacaaagca cgctgtctgg cgtctcctgc cgagcgtgcg ggcacaggcg atgccagtcg
    11341 cacgcctggc agtcacggcg cggttgcggg ttttcgctgc cacaccattt ttgtaaggtg
    11401 gcgtcaaaaa gctcaatcga gatacgactg atatctgccc gcacccaaca ctcgaacagg
    11461 gcaattaaaa atttccccca cagctctgct gtcaccgaag cggccgtcag atcgccccgg
    11521 tcatcaaatt caagataggg aatgagctgt acggagcgga tgccccgctg tttgaaattg
    11581 tgataaaaat cggcaggttg cagagcatcc ttgtactcta caaccagttt atgcctgtcc
    11641 tcttcagcat caatgacctg acttcctgtc atgcgactct ctcaataaat acgataagtt
    11701 gatgtatatg cgttacagca aacagtattg cgagagataa caccgcgagg gagatcaaaa
    11761 atttgtcacg gactacgtga aattgggaaa aatcgctatt cgtgacatcc attaaattgc
    11821 gattacgggt gtagtgccag aggatcagcg ccacgatggc gagaatgcca atcgaaatcc
    11881 agaataacat gcccgcctgg tgccagttgt gtttgatagc caacgccatc aacgcgccgt
    11941 agcccagcat ggtacgaaac cacgccagtg atgtgcgctc cggctgcagt cctgggtcgg
    12001 caatgcgtct ggctttgcgg ctatccggca tacaacacca gtcccataac gatcaccgcc
    12061 acgaccatca atattaagct aatgattaat aagctgttgg tgtagggcag gtcctctttc
    12121 agacgcatcg ctttttcatt gcgtaaccag cgcaggtagc catacattgc taacccgccg
    12181 gaaaacagac acaacaacaa cgccagcagt tcacgaatga cgggcgtggc gaaatctggc
    12241 gcaagttgat caagcccaac ccccgccgcc agaaatccta gtgcggtacg gatccacgcc
    12301 agaaaagtac gctcattagc cagcgagaag cggtaatcgg gcgcttctcc aaggcgggaa
    12361 atattcattg ttgctccttt gcaatttcac taacgctcta tctttagcgg ttttttttaa
    12421 gaatttcgtc cgcccgtttc ctgatatgct tttgccatcc gctacaagga ggtcagatgg
    12481 gtatcatagc gcaaattgac atcctccacg ccctgaagga cgtggatccc tgctacgttc
    12541 aggctgtcgc ctgaatcatt tcggtgggtt cctgcttcaa cgagcggcct gactgcacca
    12601 tctctccaca ggcaagaacg gcgtgccccg ccgctaaaat gttacgagcg ccatttacat
    12661 cggcgttcgc tgtatatcca catacctggc atctgaattt actttgtgac aggcgatttt
    12721 ctttcgctgt atgaccacag cacacgcaac gctggcttgt gtacgctggc ggaacagcaa
    12781 gcacctgacc accacgccag agctgcttgt acgcaagctg gcggcgtatt tcataccagc
    12841 cctgatccag tatcgaacgg tttaaacctg attttgcccg gacattgcgc cccggcaggc
    12901 tgaccgtacc cgctgctgac tttgacatgt tgctgacctt caaatcctca atgactatca
    12961 ttgcgtggtt tttgctgacg gtcgttgtga ctttgtgaag gtagtccctg cggatatttg
    13021 cgatacagga atgcagtcgc tgtattttgc gtttctgctt ctgccagttg ttgctgaatt
    13081 tgaccttgcg gcttaactgt cgctgaagtc tctccagcgt cttctggttt ttctgaaaac
    13141 tgtttacagg ctcaaagact gtgccatctg acagcgtggc gagtttagcc acgccagcat
    13201 ccagcccgat cattgatgct gaagggtgaa ccggagttga tacttcactt tctgtctgaa
    13261 tactgatgta ccacttaccg caggactggc tgacagtgac atttttcaca acacccgtga
    13321 cctgacggct gttccggtag cgcatccagc ccagtttcgg cagaaaaata cggctgtttt
    13381 cctgatcgag cttaacgccc tgcgggtagc ggaatgcatc attctgtccc cgctttttga
    13441 atcggggaaa agcagcccgc ttctggaaga agtttttgta agcccgctca aggcctttca
    13501 gtgactgttg caatggctgt gagggcgaat ctttaagcca ttgcgtttca gtggcgtttt
    13561 tccactcaac cagccaggaa gccattttcc cgtaagggat gtatttatta ccggcctcat
//
LOCUS       DAPGUL010000120        13598 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.122, whole genome shotgun sequence.
ACCESSION   DAPGUL010000120 DAPGUL010000000
VERSION     DAPGUL010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13598
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.122"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(70..789)
                     /gene="deoD"
                     /locus_tag="RHX21_003772"
     CDS             complement(70..789)
                     /gene="deoD"
                     /locus_tag="RHX21_003772"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDV1988896.1"
                     /translation="MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVR
                     GMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLR
                     DVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGIDARVGNLFSADLF
                     YSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAER
                     QTTFNDMIKIALESVLLGDKE"
     gene            complement(869..2092)
                     /gene="deoB"
                     /locus_tag="RHX21_003773"
     CDS             complement(869..2092)
                     /gene="deoB"
                     /locus_tag="RHX21_003773"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDV1988897.1"
                     /translation="MKRAFIMVLDSFGIGATEDAERFGDVGADTLGHIAEACAKGEAD
                     NGRKGPLNLPNLTRLGLAKAHEGSTGFIPAGMDGNAEVIGAYAWAHEMSSGKDTPSGH
                     WEIAGVPVLFEWGYFSDHENSFPQELLDKLVERANLPGYLGNCHSSGTVILDQLGEEH
                     MKTGKPIFYTSADSVFQIACHEETFGLDKLYELCEIAREELTNGGYNIGRVIARPFIG
                     DKAGNFQRTGNRHDLAVEPPAPTVLQKLVDEKHGQVVSVGKIADIYANCGITKKVKAT
                     GLDALFDATIKEMKEAGDNTIVFTNFVDFDSSWGHRRDVAGYAAGLELFDRRLPELMS
                     LLRDDDILILTADHGCDPTWTGTDHTREHIPVLVYGPKVKPGSLGHRETFADIGQTLA
                     KYFGTSDMEYGKAMF"
     gene            complement(2144..3466)
                     /gene="deoA"
                     /locus_tag="RHX21_003774"
     CDS             complement(2144..3466)
                     /gene="deoA"
                     /locus_tag="RHX21_003774"
                     /EC_number="2.4.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine phosphorylase"
                     /protein_id="HDV1988898.1"
                     /translation="MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAM
                     TIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGPIVDKHSTGGVGDVTSLMLGPMV
                     AACGGYIPMISGRGLGHTGGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSL
                     APADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSE
                     ALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVT
                     MALCVEMLISGKLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPTDFVENYAKYL
                     PTAMLTKAVYADTEGFVSEMDTRALGMAVVAMGGGRRQASDTIDYSVGFTDMARLGDQ
                     VDGQRPLAVIHAKDENSWQDAAKAVKAAIKLADKAPESTPTVYRRISE"
     gene            complement(3593..4372)
                     /gene="deoC"
                     /locus_tag="RHX21_003775"
     CDS             complement(3593..4372)
                     /gene="deoC"
                     /locus_tag="RHX21_003775"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005097947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HDV1988899.1"
                     /translation="MTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQAKTPVGNTA
                     AICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGNDDIEIALAETRAAIAYGADEVD
                     VVFPYRALMAGNEQVGFDLVKACKEACAAANVLLKVIIETGELKDEALIRKASEISIK
                     AGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAI
                     ADELFGADWADARHYRFGASSLLASLLKALGHGDGKSASSY"
     gene            4630..6180
                     /locus_tag="RHX21_003776"
     CDS             4630..6180
                     /locus_tag="RHX21_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjI family glycine radical enzyme"
                     /protein_id="HDV1988900.1"
                     /translation="MPTSHENALQQRCQQIVTSPVLSPEQKRHFLALEAENNLPYPQL
                     PAEARRALDEGVICDMFEGHAPYKPRYVLPDYARFLANGSEWLELEGAKDLDDALSLL
                     TILYHHVPSVTSMPVYLGQLDALLQPYVRILTQDEIDVRIKRFWRYLDRTLPDAFMHA
                     NIGPSDSPITRAILRADAELKQVSPNLTFIYDPEITPDDLLLEVAKNICECSKPHIAN
                     GPVHDKIFTKGGYGIVSCYNSLPLAGGGSTLVRLNLKAIAERSESLDDFFTRTLPHYC
                     QQQIAIIDARCEFLYQQSHFFENSFLVKEGLINPERFVPMFGMYGLAEAVNLLCEKEG
                     IAARYGKEAAANEVGYRISAQLAEFVANTPVKYGWQKRAMLHAQSGISSDIGTTPGAR
                     LPYGDEPDPITHLQTVAPHHAYYYSGISDILTLDETIKRNPQALVQLCLGAFKAGMRE
                     FTANVSGNDLVRVTGYMVRLSDLEKYRAEGSRTNTTWLGEEAARNTRILERQPRVISH
                     EQQMRFSQ"
     gene            6152..7015
                     /locus_tag="RHX21_003777"
     CDS             6152..7015
                     /locus_tag="RHX21_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjW family glycine radical enzyme activase"
                     /protein_id="HDV1988901.1"
                     /translation="MNSRCALVSKIIPFSCVDGPGSRLALFLQGCNLRCKNCHNPWTM
                     GRCNDCGECVPQCPHQALQIVDGKVLWNAVVCEQCDTCLKMCPQHATPMAQSMSVDEV
                     LSHVRKAVLFIEGITVSGGEATTQLPFVVALFTAIKNDPQLRHLTCLVDSNGMLSETG
                     WEKLLPVCDGAMLDLKAWGSECHQQLTGRDNQQIKRSICLLAERGKLAELRLLVIPDQ
                     VDYLHHIDELATFIKRLGDVPVRLNAFHAHGVYGEAQSWASATPEDVEPLADALKVRG
                     VSRLIFPALYL"
     gene            complement(7128..7910)
                     /locus_tag="RHX21_003778"
     CDS             complement(7128..7910)
                     /locus_tag="RHX21_003778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313363.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDV1988902.1"
                     /translation="MICRFIDTHCHFDFPPFSGDEEASLQRAAQAGVGKIIVPATEAE
                     NFARVQALAEKYQPLYAALGLHPGMLEKHSDVSLDQLQQALERRPAKVVAVGEIGLDL
                     FGDDPQFERQQWLLDEQLKLAKRYDLPVILHSRRTHDKLAMHLKRHDLSRTGVVHGFS
                     GSLQQAERFVQLGYKIGVGGTITYPRASKTRDVIAKLPLASLLLETDAPDMPLNGFQG
                     KPNRPEQAARVFDVLCELRPEPEDEIAEVLLNNTYAVFSVRG"
     gene            complement(7907..8980)
                     /locus_tag="RHX21_003779"
     CDS             complement(7907..8980)
                     /locus_tag="RHX21_003779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin family protein"
                     /protein_id="HDV1988903.1"
                     /translation="MGQRIPVTLGNIAPLSLRPFQPGRIALVCEGGGQRGIFTAGVLD
                     EFMRAQFNPFDLYLGTSAGAQNLSAYICNQPGYARKVIMRYTTKREFFDPLRFVRGGN
                     LIDLDWLVEATASQMPLQMDTAARLFDSGKSFYMCACRQDDYAPNYFLPTKQNWLDVI
                     RASSAIPGFYRSGVSLEGINYLDGGISDAIPVKEAARQGAKTLVVIRTVPSQMYYTPQ
                     WFKRMERWLGDSSLQPLVNLVQHHETSYRDIQQFIEKPPGKLRIFEIYPPKPLHSIAL
                     GSRIPALREDYKLGRLCGRYFLATVGKLLTEKAPLTRHLVPVVTPESIVIPPAPVAND
                     TLVAEVSDAPQANDPTFNNEDLA"
     gene            complement(9102..9263)
                     /locus_tag="RHX21_003780"
     CDS             complement(9102..9263)
                     /locus_tag="RHX21_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1328 domain-containing protein"
                     /protein_id="HDV1988904.1"
                     /translation="MFRWGIIFLVIALIAAALGFGGLAGTAAGAAKIVFVVGIILFLV
                     SLFMGRKRP"
     gene            complement(9390..9995)
                     /gene="osmY"
                     /locus_tag="RHX21_003781"
     CDS             complement(9390..9995)
                     /gene="osmY"
                     /locus_tag="RHX21_003781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone OsmY"
                     /protein_id="HDV1988905.1"
                     /translation="MTMTRLKISKTLLAVMLTSAVATGSAYAENNAQTTNESAGQKVD
                     SSMNKVGNFMDDSAITAKVKAALVDHDNIKSTDISVKTDQKVVTLSGFVESQAQAEEA
                     VKVAKGVEGVTSVSDKLHVRDAKEGSVKGYAGDTATTSEIKAKLLADDIVPSRHVKVE
                     TTDGVVQLSGTVDSQAQSDRAESIAKAVDGVKSVKNDLKTK"
     gene            complement(10388..11974)
                     /gene="prfC"
                     /locus_tag="RHX21_003782"
     CDS             complement(10388..11974)
                     /gene="prfC"
                     /locus_tag="RHX21_003782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HDV1988906.1"
                     /translation="MTSLLAAEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAGT
                     VKGRGSNQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRTL
                     TAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVENE
                     LKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQSGKGHTIQEVRIVKGLNNPDLDAAV
                     GEDLAQQLRDELELVKGASNEFDKELFLAGEITPVFFGTALGNFGVDHMLDGLVEWAP
                     APMPRQTDTRTVEASEDKFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQVR
                     TAKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPNF
                     APELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVVS
                     RLKSEYNVEAVYESVNVATARWVECADAKKFEEFKRKNESQLALDGGDNLAYIATSMV
                     NLRLAQERYPDVQFHQTREH"
     gene            12194..12454
                     /locus_tag="RHX21_003783"
     CDS             12194..12454
                     /locus_tag="RHX21_003783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001217545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinI-like family protein"
                     /protein_id="HDV1988907.1"
                     /translation="MRIEICIAKEKMTKMPNGAVDALKEELTRRISKRYDDVEVIVKA
                     TSNDGLSVTRTTDKDLAKTFVQETLKDTWESADEWFVYSNHK"
     gene            12812..>13598
                     /locus_tag="RHX21_003784"
     CDS             12812..>13598
                     /locus_tag="RHX21_003784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005025120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HDV1988908.1"
                     /translation="MHNFALANKKSPDFISELPQIEPKPYSNGHKIKWINHTLTSTEV
                     TPPDNLIKICILIESGEITITSVSDIANLLGVPAGQLLYILYHKKDNYRTFEIEKKNG
                     KKRVINAPCGGLSILQTRLKPVLEYFYRPKKSAHGFIKGKSIITNAGMHIKKNFVVNI
                     DLENYFESISFARVYGIFKSKPFNFAHPAATVLAQLCTHNGKLPQGACTSPILANIAS
                     ASLDKQLTQFAGRKKISYSRYADDITFSFNQRNIDIIKKNDDGS"
BASE COUNT         3338 a         3546 c         3383 g         3331 t
ORIGIN      
        1 agatactaaa aagccggagc agtctcccac tccggcttca cacgacaatc gcctttcagc
       61 gaaacacaat tactctttat cgcccagcag aacggattcc agtgcgattt tgatcatgtc
      121 gttgaaggtg gtctgacgct cagcggcagt ggtctgctcg tgagtgcgga tgtggtcaga
      181 cacggtacag atggtcaggg ctttcgcgcc aaattctgca gcgacgccgt agataccagc
      241 cgcttccatt tccacgccga ggatgccgta tttttccatc acgtcgaaca tttcgccgtc
      301 cggagagtag aacaggtcag cggagaacag gttaccaacg cgagcatcaa tgcccagtgc
      361 tttagccgcg tctaccgcgt tacgcaccat gtcaaagtca gcgatagcgg caaagtcatg
      421 atctttaaaa cggatgcggt taactttgga atcggtgcag gcacccatac cgataacgac
      481 gtcgcgcagt tttacgtgcg gcagaactgc gccacaggaa cccacgcgga taattttctt
      541 cacgccgaaa tcggtgatca gttctttggt gtagatggag caggacggga tacccatacc
      601 gtgacccatt acggaaattt tgcggccttt ataagtaccg gtgaagccca gcataccgcg
      661 aacgttgttc acttcacggg catcttcaag gaaagtttca gcaatatact ttgcacgcag
      721 cgggtcgcct ggcatcaaaa ctacgtcagc gaaatcgccc atttctgcat taatgtgtgg
      781 ggtagccatt gttttatcct tatctacatg ttttcaccct ctccctgagg gagagggccg
      841 gggtgagggc atcaagccgc acccattatc agaacatggc tttgccatat tccatatcag
      901 aagtaccaaa atattttgcc agagtctggc cgatatccgc gaaggtttca cggtgaccca
      961 gtgagcccgg ttttactttc gggccgtaaa ccagtaccgg aatgtgttca cgcgtgtgat
     1021 cagtaccggt ccaggtcgga tcacaaccgt ggtcagcagt gaggatcagg atgtcgtcat
     1081 cgcgcagcag agacatcagc tccggcagac ggcggtcgaa cagttccaga cccgccgcat
     1141 aacctgcgac gtcgcgacgg tggccccagg aagagtcgaa gtcaacgaag ttggtgaaga
     1201 cgatggtgtt atcacccgct tctttcatct ctttgatggt ggcgtcaaac agcgcgtcca
     1261 ggccagttgc tttcactttc ttggtgatac cgcagttggc gtagatgtct gcaattttac
     1321 cgacagaaac cacctgaccg tgtttttcat caaccagttt ctgcagcacg gtcggtgctg
     1381 gcggctcaac agccaggtcg tgacggttac cggtacgctg gaagttaccg gctttgtcgc
     1441 caataaacgg acgagcgata acacgaccga tgttgtagcc gccgttggtc agctcttcac
     1501 gggcgatttc gcacagttcg tagagtttat ccaagccaaa ggtttcttcg tggcaggcaa
     1561 tctggaacac ggagtcagcg gaggtataga aaatcggctt gccggttttc atgtgctctt
     1621 cgcccagctg atccagaatg accgtaccgg aagagtggca gttaccgaga taaccaggca
     1681 ggttagcgcg ttcaaccagt ttatccagca gctcttgcgg gaagctgttt tcgtgatcgg
     1741 agaagtatcc ccactcaaac agaaccggga caccggcgat ttcccagtga ccagacgggg
     1801 tatctttacc ggatgacatt tcgtgcgccc atgcgtacgc gccgataact tcagcgttgc
     1861 cgtccattcc tgccggaatg aaaccggtag aaccttcatg tgctttcgcc agccccagac
     1921 gggtcagatt tggcagattg agcgggcctt tacgaccgtt atcagcttcg cctttggcac
     1981 aggcttctgc gatatgaccc agggtgtcag ccccgacgtc accaaagcgt tctgcatctt
     2041 ctgtagcgcc gatgccgaat gagtccagca ccataataaa tgcacgtttc atatgttctc
     2101 cgtactcagt gcttcaaatt taaatgatca gatcagtata ccgttattcg ctgatacggc
     2161 gatagacagt tggtgtgctt tccggtgctt tatcggcaag tttaattgcc gctttcaccg
     2221 ctttcgccgc gtcctgccag ctgttttcgt ctttcgcgtg gataacagcc agcggacgct
     2281 gaccgtctac ctggtcgccc aaacgcgcca tatcagtaaa gccgacgctg taatcaatgg
     2341 tgtcagatgc ctgacgacga ccgccgccca ttgcaaccac tgccatcccc agcgcgcggg
     2401 tatccatttc actgacaaaa ccttcggtat cagcatagac tgctttcgtc agcatcgctg
     2461 tcggcagata cttcgcgtag ttctcaacga agtcggttgg gcctttttgt gccgctacca
     2521 tacgaccaaa gacttctgcc gctttaccgt tgtccagcac tgcttgcaat ttcgcgcgcg
     2581 cttcggcgtc atctttcgcc agtttgccgg agataagcat ctccacgcac agcgccatcg
     2641 tgacatcaaa cagacgcggg ttacgatatt cccccgtcag gaactgcacc gcttcacgaa
     2701 cttcaaccgc gttacctgca ctggaggcca gtacctgatt catatcggtg agcagcgcgg
     2761 tggtgcgcac gccagcgccg ttagccacgc caacaatcgc ttcggcaagg gcttcagaga
     2821 gttcgtaggt cggcataaac gcgccgctac ccactttcac gtccatcacc agcgcatcca
     2881 gaccttccgc cagtttcttc gccaggatcg aggcagtgat cagcgggatg gagtccacgg
     2941 ttgcggtaat atcacgggtc gcgtagaaac gtttatccgc cggagccagt gagctggtct
     3001 ggccgataat cgctacgccg acgtctttaa taatttcgcg gaaacggttg tcatccggga
     3061 aaatgtcgaa gccagggatg gattccagtt tgtcgagcgt accgccagta tgaccgaggc
     3121 cgcgaccgga gatcatcgga atatagccgc cgcaggctgc gaccatcggc cccaacatca
     3181 gcgaagtcac atcgccgacg ccgccggtgg agtgtttatc aacaatcggg ccattcagat
     3241 gcaggctttt ccagtcgaga acggttcctg aatctcgcat cgccatggtc agcgagacac
     3301 gctcaggcat tgtcatatcg tggaagaaaa tggtcatcgc gagggcggca atctgccctt
     3361 cggagatagt gttgtcgcga ataccgttga taaagaaacg aatttcttca tcgcttagcg
     3421 catgaccatc acgtttttta cgaataattt cttgtgcgag aaacaaggta acctcccgag
     3481 gaaaagagta tgaggcggct tttgccggat gcgtctacgc cttatccggc ctacgggtag
     3541 atacgtctcg taggcctgat aagcgcagcg catcaggcgt aaagcatctt acttagtagc
     3601 tgctggcgct cttaccgtca ccgtggccca gcgctttcaa caggcttgcc agcaggctgg
     3661 aagcaccaaa gcggtagtga cgcgcatctg cccagtcagc accgaacagt tcatctgcga
     3721 tggcgagata tttctgcgca tcttccgcag tacgcacgcc gcccgctggt ttgaaaccaa
     3781 cggttttttc tacgcccata tcacggatca cttccatcat gatgcgcgcg ctttccggcg
     3841 tcgcgttcac agccacttta ccggtagagg ttttgatgaa gtccgcaccc gctttgatgg
     3901 agatttcaga cgctttacgg atcagcgctt cgtctttcag ttcgccggtt tcgatgatca
     3961 ctttcagcag tacattcgct gccgcgcaag cctctttaca ggctttcacc aggtcaaaac
     4021 caacctgctc gttacccgcc atcagcgcgc ggtacgggaa cacaacgtca acttcatcag
     4081 caccgtaggc gattgccgca cgggtttctg ccagcgcgat ttcgatgtca tcgttaccgt
     4141 gtgggaagtt ggttaccgta gcgattcgga tttccggggt gccctgctct ttcagcgttt
     4201 tgcgagcaat cgggataaag cgaggataga tacagatagc ggcggtattg ccgaccggag
     4261 ttttggcctg atgacacaga gcaattactt tctcgtcggt gtcgtcgtca ttcagggtgg
     4321 tcaggtccat caatttcagt gcacgcaggc tgcttgcttt cagatcagtc atttcattct
     4381 cctggcttgt cgccaataaa attcaccttg cgagtttgtt agtattctaa catctactcc
     4441 gcaacacact tcgatataca tcacaattaa ggaaatctac ttacaagttt gcatcactgt
     4501 aatgcgatct ggttcaaata attcactttc aaatgaatgc gtcagtggtg gcaaacgcat
     4561 caggatcaaa gtgaacatca cgaaacttct tacaatggcg catcaccttc ggcataaaag
     4621 gaaaagaaga tgcccacttc tcatgaaaat gcactgcaac aacgttgcca gcaaattgtc
     4681 accagcccag tgcttagccc ggagcagaag cgccattttc tggctctgga agcagaaaac
     4741 aatctgcctt atccgcagct tcctgccgaa gcccgccgcg cgctggatga gggtgtaatc
     4801 tgcgatatgt ttgaaggtca tgcgccgtac aaaccgcgct atgtcttacc cgattacgcc
     4861 cgttttctgg cgaacggttc cgaatggctg gagctggaag gcgcgaaaga tcttgatgac
     4921 gcactctctc tgctgaccat tctttaccac cacgtaccgt cggtcacatc gatgccggtc
     4981 tacctggggc aactggatgc gttgttgcaa ccgtatgtta gaattctaac acaagacgag
     5041 atcgatgttc gaataaaacg tttctggcgt tacctcgaca gaaccctgcc agacgccttt
     5101 atgcacgcca atatcggccc gtctgattcg cccattaccc gtgcaatctt acgtgcagac
     5161 gcagagttga agcaggtttc accgaacctg acctttatct acgatcctga aatcacccct
     5221 gatgacctgc tgctggaagt ggcgaagaac atctgtgaat gtagcaaacc gcacatcgcc
     5281 aacggtccgg tgcatgataa aattttcaca aaagggggct acgggattgt gagctgttac
     5341 aactcactgc cgctggcggg tggtggcagc acgctggtac gccttaacct gaaagccatt
     5401 gccgagcgca gcgaatcgct ggatgacttc tttacgcgca ctctaccgca ctactgccag
     5461 cagcagatcg ccatcatcga tgcgcggtgt gaattcctct atcaacaatc acacttcttt
     5521 gagaatagct tcctggtgaa agaagggctg attaaccctg aacgttttgt gccaatgttt
     5581 ggcatgtatg ggctggcgga agcggttaac ttgctgtgtg agaaagaagg gattgccgca
     5641 cgttacggta aagaagccgc cgcaaatgaa gtgggttatc gcatcagcgc gcaactggcg
     5701 gagtttgtcg ccaatacccc cgtgaaatat ggatggcaaa aacgcgccat gttacacgca
     5761 cagtcgggga tcagttccga tattggcacc acgccgggcg cgcgtttgcc gtatggcgat
     5821 gagccagatc cgatcaccca tctgcaaact gtcgccccgc atcatgctta ttattattcc
     5881 ggcatcagcg acattctgac gctcgacgaa accatcaaac gtaacccgca ggcactggta
     5941 cagctttgcc tcggtgcctt taaagccgga atgcgtgaat ttaccgccaa tgtcagcggt
     6001 aacgatctgg ttcgcgttac cggttatatg gtacgtttgt cggacttaga aaaatatcgc
     6061 gccgaaggtt cacgcaccaa caccacctgg ctgggcgaag aagccgcacg caacactcgt
     6121 attctggaac gccagccgcg cgtgataagc catgaacagc agatgcgctt tagtcagtaa
     6181 gattatcccc ttctcctgcg ttgacgggcc aggtagtcgt ctggctctgt ttttgcaggg
     6241 ctgcaatctg cgctgcaaaa actgtcacaa tccgtggacg atgggacgct gcaatgattg
     6301 cggagagtgc gtgccacagt gtccgcatca ggcgttgcag attgttgacg gcaaagtgct
     6361 gtggaacgct gtggtctgcg agcagtgtga tacctgcctg aagatgtgtc cgcaacatgc
     6421 cacgccaatg gcgcaatcca tgagcgtgga cgaagtgctt agccatgtcc gcaaagcggt
     6481 gctgtttatt gaagggataa cggtaagcgg cggcgaagcc acgacccaac tgccgtttgt
     6541 agtggcgcta tttacagcca tcaaaaacga tccgcaactg cgccacctca cctgcctcgt
     6601 ggacagtaac ggtatgttga gcgaaaccgg ctgggaaaaa ttactcccgg tgtgcgacgg
     6661 cgcgatgctc gatctcaaag cgtgggggag cgaatgtcat cagcaattaa ccggacgcga
     6721 taatcagcag attaagcgca gcatctgttt gctggcagag cgcggtaagc tggcggaact
     6781 gcgtttgctg gtaattccag accaggtgga ttatttgcat cacatcgatg agctggcgac
     6841 gtttatcaag agacttggcg atgttccggt tcgcctgaat gcgtttcatg cccacggcgt
     6901 gtatggcgag gcgcaaagct gggcgagcgc cacgccggaa gacgttgagc cgttggctga
     6961 tgcgttaaag gtgcgcgggg tgagccggtt gatatttccg gcgctctatt tgtgacatgc
     7021 cggatacggc ctacggttcg gcacaaacct gtaggcatga taagacgcga caagcgtcgc
     7081 atcaggcatt atgcgccgac tgccggatgc tgcctacgaa gggtaaacta cccacgaacg
     7141 ctaaacaccg catacgtatt attaagcaac acttcggcaa tctcatcttc tggttccgga
     7201 cgtaactcgc aaagcacgtc aaacacccgc gcagcctgtt ccgggcggtt aggcttcccc
     7261 tgaaagccgt tgagcggcat atccggcgcg tcggtttcca gcaacaacga tgccagcggt
     7321 aattttgcga tgacatcgcg ggttttactg gcgcgtggat aggtgatagt accgcctacg
     7381 ccgattttgt agcccagctg tacaaaccgc tcggcctgtt gcaggctgcc ggaaaaaccg
     7441 tgaaccacgc cagtgcgcga taaatcgtgg cgtttaagat gcatcgccag tttgtcgtgt
     7501 gtgcgccgtg aatgcaggat caccggcaga tcgtagcgtt tcgccagttt cagctgttcg
     7561 tcgagtaacc actgttgcct ctcaaattgc ggatcgtcgc cgaagagatc cagaccgatc
     7621 tcccccaccg ccaccacctt cgccggacgc ctttccagcg cctgctgtag ctgatcaaga
     7681 gacacatcgc tatgtttttc caacatcccc ggatgcaacc ccaatgcggc atacagcggt
     7741 tgatattttt ccgctaacgc ctgcacgcgg gcaaaatttt ccgcctctgt cgccggaaca
     7801 atgatcttgc ctacgcccgc ttgtgccgcg cgttgcaggc tggcctcttc atcgccacta
     7861 aacggcggga aatcaaaatg gcagtgggta tcgataaaac ggcaaatcaa gccagatcct
     7921 cattgttaaa tgtcgggtcg ttcgcctgcg gagcatcgct cacttcggca accagcgtat
     7981 cgttggcgac tggcgcaggc ggaataacga tcgattccgg cgtcaccact ggcaccagat
     8041 ggcgggtaag cggcgctttt tcagttaata gcttgccaac cgtggcgagg aaataacgac
     8101 cgcataaacg cccaagttta tagtcttcac gcagcgccgg aatccgactg ccaagcgcga
     8161 tactatgtaa tggcttcggt ggataaattt cgaatatccg cagcttgcca ggtggtttct
     8221 caataaattg ctgaatgtca cgatagctgg tttcatgatg ctgcaccaga ttgaccagcg
     8281 gctgcaggct actgtcaccc agccagcgtt ccatgcgttt gaaccactgc ggcgtgtagt
     8341 acatttgtga cggcacagtg cggatgacga ccaacgtttt agcgccctgc cttgccgcct
     8401 ctttaaccgg aatcgcatca ctgatcccgc catccaggta gttaatgcct tccagcgaca
     8461 ctccgctacg ataaaagcca ggtatcgcac tggaggcgcg aatcacatcc agccagtttt
     8521 gtttggttgg taaaaagtaa ttcggcgcgt agtcatcctg acgacaggcg cacatataaa
     8581 acgatttgcc gctgtcaaac aaccgcgcgg cggtatccat ttgcaacggc atctgacttg
     8641 cggtggcctc caccagccag tcgagatcga taagatttcc tccacggaca aagcgcaatg
     8701 gatcgaaaaa ttcgcgtttt gtggtatagc gcatgatgac tttgcgcgcg taaccgggct
     8761 gattgcagat atacgccgag aggttctgcg ccccggcaga tgtgccgaga taaagatcga
     8821 aaggattaaa ctgcgcgcgc ataaactcat ccagcacgcc agccgtgaaa attccacgct
     8881 gtccgccgcc ttcgcacacc agagctattc gtccaggctg gaacggcctt agcgacaacg
     8941 gcgcaatatt accaagcgtt acaggtattc gctgccccac ctctgccttc ctgtttttgt
     9001 tgtgaaagaa tgacaaagta acgcaattta ttattcgcta aaaccgcaaa agccagtccg
     9061 ctggactggc tttggataaa attttcttaa tggtctgaaa tctagggtcg ttttcggccc
     9121 atgaacaaac tcaccaggaa cagaataatc ccgacgacaa agacaatttt agctgcgcct
     9181 gcagcggtac cggccagacc accaaaccca agtgcggcgg cgattaacgc gataaccaga
     9241 aatatgatgc cccaacgaaa cataagcgtc tcctttacca tagttaatgt caccgcttga
     9301 tatgagcgtg aaaatcactc aatgcgatat ttttagtgtg gtgcacatcg cgcctcccga
     9361 caaagttcgg gaggacgaat tacgacgaat tacttagttt tcagatcatt tttaacgctt
     9421 ttcacaccat ctaccgcttt ggcgatactt tcagcacggt cgctctgtgc ctgggaatcg
     9481 acggtaccgg agagctgaac cacgccgtcg gtggtttcaa ctttcacatg acgggaaggg
     9541 acgatatcgt ccgccagcag tttggctttg atttcactgg tggtggcggt gtcacccgcg
     9601 tagcccttca ccgagccttc tttagcgtcg cgaacgtgca gtttgtcgct gacagaggtc
     9661 accccttcaa cgcctttcgc cactttcact gcctcttcgg cctgagcctg gctttcaacg
     9721 aaaccgctca gggtcacgac tttttgatcg gttttgacag agatatcggt gctcttgatg
     9781 ttgtcatgat ccaccagcgc cgccttcact ttcgcggtga tggcgctgtc atccatgaaa
     9841 ttaccgactt tattcataga gctatcgact ttttgccctg cgctttcatt ggtagtctgt
     9901 gcgttgtttt ccgcgtaggc agagccggtc gcgacggcag aggtcaacat tacagccagc
     9961 agagttttcg aaatcttcag tcttgtcata gtcatcgatt tattcctgta tgtttgctcg
    10021 taatttgagc ctggcaacac gaggttgcat tgctgaatag ggagagactt caccctctac
    10081 agaagtcaat ggtcgccatc acaaaagcga tgggtgatga ataacgacca ttacagcctc
    10141 tgaatcagtt attaatatcg gtagaatgac aatcgacggc tttagatact gatatctacg
    10201 cattgaacgg tatttaacgc cgtcagaaat gtcattactt tgttaaatat agttcacaat
    10261 tttgaaaccg ctcgggatat cagcgaaaac ataagcaaaa gtgaatgttt taagaacatt
    10321 ccgtaagcgg ctaataagga agggaaattg acagggcgca gcggctaccg cgccctggag
    10381 gcaagaatta atgctcgcgg gtctggtgga actgaacgtc gggataacgt tcctgcgcca
    10441 ggcgcaggtt gaccatgctg gtagcgatgt aagcgaggtt atcgccgcca tcaagcgcca
    10501 gttggctttc gttcttacgc ttgaactctt cgaatttctt cgcgtccgca cattctaccc
    10561 agcgggcagt ggcaacgttg actgattcat atactgcttc aacgttgtat tcgctcttca
    10621 ggcgcgatac caccacatca aactgcagca caccaacagc accaacgatc aaatcgttgt
    10681 tggagatcgg acggaacacc tgcaccgcgc cctcttcgga aagctgtacc agccctttga
    10741 gcagctgttt ttgcttcagc ggatctttca ggcggatacg acggaacagt tctggtgcga
    10801 agttcggaat accggtgaac ttcatcatct caccctgggt aaaggtgtcg ccgatctgaa
    10861 tagtgccgtg gttgtgcagg ccgaggatat cgcccggata cgcttcttca acgtgcgaac
    10921 ggtcgcccgc cataaaggtc agcgcgtcgg agataaccac atctttcgca gtacgcacct
    10981 ggcgcagctt catgcctttt tcatatttac cggatactac gcgcataaac gccacgcggt
    11041 cgcggtgttt cgggtccatg ttggcctgaa ttttaaatac gaagccggta aatttgtctt
    11101 cgctcgcctc tacggtacgg gtatcagtct gacgcggcat cggcgcagga gcccactcca
    11161 ccaggccatc cagcatatga tcaacaccga agttacccag cgcagtaccg aagaataccg
    11221 gagtgatttc gcccgcaagg aacagttctt tgtcgaactc gttagacgcg cctttcacca
    11281 gttccagttc gtcacgtagc tgctgtgcca gatcttcacc aaccgcagcg tcgagatccg
    11341 ggttattcag ccctttaaca atacggactt cctgaatcgt gtggccttta ccgctctgat
    11401 agagataggt ttcgtcttta taaaggtggt aaacgccttt aaacagcttg ccgcagccaa
    11461 tcggccaggt gatcggtgcg cagccgattt tcagctcgtt ctcaacttca tcgagcagtt
    11521 ccatcgggtc gcggatatca cggtcaagtt tgttcataaa ggtgaggatc ggcgtgtcgc
    11581 gcagacgggt aacttccatc agcttacggg tacgatcttc aacacctttt gcagcgtcga
    11641 taaccatcag gcagcagtcc accgccgtca gggtacgata ggtatcttcc gagaagtctt
    11701 cgtgccccgg ggtgtcgagc aggttaacca ggcaatcgtg atacggaaac tgcatcacag
    11761 acgtagtaat ggagatccca cgctgctttt ccatctccat ccagtccgac ttagcgtgct
    11821 ggttggaacc acggcctttt actgtaccgg cggtctgaat ggcctgtccg aacagcagca
    11881 ccttctcggt gatggtagtc ttaccggcat ccgggtgaga aataattgca aaggttcttc
    11941 ttttcgctac ctctgcggcc aaaaggcttg tcataattgt tgtctctttg attatgtaca
    12001 atcatatgta caaagaaaaa ttcatgccgc tgattgtaca ttttggaggt atcagagcat
    12061 agcagaacat gatcagtagg tgtatttgta gccaaagaac atttgtacat gcagcaatct
    12121 ttgctctatt gacactgttt atttatacag ttaaaaataa tgctgtatgc aaacacagtg
    12181 tagagggagt tttatgcgta ttgagatctg catagccaaa gagaaaatga ctaaaatgcc
    12241 aaacggtgct gtggatgcgt taaaggaaga attaacccga cgcatcagta agcgttatga
    12301 cgatgtagag gtgatcgtaa aagccaccag caatgatggc ctttctgtta cgcgcaccac
    12361 tgataaagat ttagctaaaa cttttgttca ggaaactctg aaagatacct gggagtctgc
    12421 tgacgagtgg tttgtatact ccaaccataa atgaagttaa tgactattgt gagcgagaaa
    12481 cgcgctacta ctatatagac agacaagatg cacttactga ataaatactc ataacggaga
    12541 aaccagctgt atagtgaaca atagatttcc agtagcatat ttttacttca cttttagtta
    12601 ttaatatgat aatcataaac tacggctctg ccttaaattt gtgaggttgt ttcgcctcga
    12661 aggaactaat gttaggacat acgccaccgt tcagtcgatg gtaacgcttc ttaactagtg
    12721 gtccgctaag tgatgcgcaa agtgattggg cagagccgaa acgtttacaa tccgatagga
    12781 gttggttttg tcgctacatg ataaattatt aatgcataac ttcgcattag ccaataaaaa
    12841 aagccctgac ttcatatctg aacttcctca aattgaacct aaaccataca gcaatggaca
    12901 taaaattaaa tggataaacc acacacttac tagcactgaa gttactcccc ctgataacct
    12961 gattaaaata tgcatattga ttgagtcagg ggaaattact ataacatcag taagtgatat
    13021 tgccaattta cttggagttc ctgctggcca attactttat atactatatc ataaaaaaga
    13081 taattatcgt acttttgaaa tagaaaagaa gaatggtaaa aaaagagtca ttaatgctcc
    13141 ttgtggcggt ctatcgatac tccaaacgag actaaagcct gttcttgaat atttctacag
    13201 gccaaagaaa tctgctcatg gttttataaa aggaaagagc atcattacta atgctgggat
    13261 gcatattaaa aaaaattttg tcgtaaacat tgacctagaa aactatttcg aatcaataag
    13321 ttttgccagg gtttatggaa tatttaaaag taaacctttt aattttgctc atccagcagc
    13381 tactgtttta gctcagttat gtactcacaa tggaaaatta cctcaaggtg cgtgtacatc
    13441 gccaatatta gcaaatattg catcagcttc tctagacaaa cagctcaccc aatttgcagg
    13501 aagaaaaaaa atatcttatt ctaggtatgc tgacgacata actttttctt tcaatcagag
    13561 aaatattgat ataatcaaaa aaaacgacga cggaagtt
//
LOCUS       DAPGUL010000121        13597 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.123, whole genome shotgun sequence.
ACCESSION   DAPGUL010000121 DAPGUL010000000
VERSION     DAPGUL010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13597)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13597)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13597
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.123"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            5..829
                     /locus_tag="RHX21_003785"
     CDS             5..829
                     /locus_tag="RHX21_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001707419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2686 family protein"
                     /protein_id="HDV1988909.1"
                     /translation="MPLSNALQSQIITDDHFLHHPKVDNELTRKYERARLDTENIYLL
                     PLTRGNNHNYDGKSVVEIRKLDISKESWPFNYVTETCRESDGITTTGRMLYRNLRITS
                     ALDEIYGGICKKAHAATELAEGLRLNLFMKSPFAPVEDYTVHEITLGPGCNVPGYAGT
                     TIGYISTLPVSQAKRWTNEQPRIDIYIDQIITVSGVANSSGFALAALLNANIEMGNDP
                     IIGIEAYPGTAEIHAKMGYKVIPGDEDAPLKRMTLQPSSLPELFELKNGEWNYIGK"
     gene            complement(970..1743)
                     /gene="uxuR"
                     /locus_tag="RHX21_003786"
     CDS             complement(970..1743)
                     /gene="uxuR"
                     /locus_tag="RHX21_003786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Uxu operon transcriptional regulator"
                     /protein_id="HDV1988910.1"
                     /translation="MKSATSAQRPYQEVGAMIRDLIIKTPYNPGERLPPEREIAEMLD
                     VTRTVVREALIMLEIKGLVEVRRGAGIYVLDSSGSHNTDSPDANVCNDAGPFELLQAR
                     QLLESNIAEFAALQATREDIVKMRQALQLEERELASSAPGSSESGDMQFHLAIAEATH
                     NSMLVELFRQSWQWRENNPMWIQLHSHLDDSLYRKEWLGDHKQILAALIKKDARAAKL
                     AMWQHLENVKQRLLEFSNVDDIYFDGYLFDSWPLDKVDA"
     gene            complement(1958..3418)
                     /locus_tag="RHX21_003787"
     CDS             complement(1958..3418)
                     /locus_tag="RHX21_003787"
                     /EC_number="1.1.1.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructuronate reductase"
                     /protein_id="HDV1988911.1"
                     /translation="MTTIVDSNLPVARPSWDHSRLESRIVHLGCGAFHRAHQALYTHH
                     LLESTDSDWGICEVNLMPGNDRVLIENLKKQQLLYTVAEKGAESTELKIIGSMKEALH
                     PEIDGCEGILNAMARPQTAIVSLTVTEKGYCADAASGQLDLNNPLIKHDLENPTAPKS
                     AIGYIVEALRLRREKGLKAFTVMSCDNVRENGHVAKVAVLGLAQARDPQLAAWIEENV
                     TFPCTMVDRIVPAATPETLQEIADQLGVYDPCAIACEPFRQWVIEDNFVNGRPDWDKV
                     GAQFVADVVPFEMMKLRMLNGSHSFLAYLGYLGGYETIADTMTNPDYRKAAFALMMQE
                     QAPTLSMPEGTDLNAYATLLIERFSNPSLRHRTWQIAMDGSQKLPQRLLDPVRLHLQN
                     GGSWRHLALGVAGWMRYTQGVDEQGNAIDVVDPMLAEFQKINAQYQGADRVKALLGLS
                     GIFADDLPQNADFVGAVTTAYQQLCERGARECVAAL"
     gene            complement(3499..4683)
                     /gene="uxuA"
                     /locus_tag="RHX21_003788"
     CDS             complement(3499..4683)
                     /gene="uxuA"
                     /locus_tag="RHX21_003788"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709912.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HDV1988912.1"
                     /translation="MEQTWRWYGPNDPVSLADVRQAGATGVVTALHHIPNGEVWSVEE
                     ILKRKAIVEDAGLVWSVVESVPIHEDIKTHTGNYEQWIANYQQTLRNLAQCGIRTVCY
                     NFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAE
                     RFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKA
                     IIPVAEEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYG
                     VRADNDLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNGDVDMYEVVKAIVEEE
                     HRRKAEGKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFF
                     SR"
     gene            5023..6366
                     /gene="gntP"
                     /locus_tag="RHX21_003789"
     CDS             5023..6366
                     /gene="gntP"
                     /locus_tag="RHX21_003789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate permease GntP"
                     /protein_id="HDV1988913.1"
                     /translation="MHVLNILWVVFGIGLMLVLNLKFKINSMVALLVAALSVGMLAGM
                     DLMSLLHTMKAGFGNTLGELAIIVVFGAVIGKLMVDSGAAHQIAHTLLARLGLRYVQL
                     SVIIIGLIFGLAMFYEVAFIMLAPLVIVIAAEAKIPFLKLAIPAVAAATTAHSLFPPQ
                     PGPVALVNAYGADMGMVYIYGVLVTIPSVICAGLILPKFLGNLERPTPSFLKADQPVD
                     MNNLPSFGVSILVPLIPAIIMISTTIANIWLVKDTPAWEVVNFIGSSPIAMFIAMVVA
                     FVLFGTARGHDMQWVMNAFESAVKSIAMVILIIGAGGVLKQTIIDTGIGDTIGMLMSH
                     GNISPYIMAWLITVLIRLATGQGVVSAMTAAGIISAAILDPATGQLVGVNPALLVLAT
                     AAGSNTLTHINDASFWLFKGYFDLSVKDTLKTWGLLELVNSVVGLIIVLIISMVA"
     gene            complement(6610..7512)
                     /gene="fimH"
                     /locus_tag="RHX21_003790"
     CDS             complement(6610..7512)
                     /gene="fimH"
                     /locus_tag="RHX21_003790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria D-mannose specific adhesin FimH"
                     /protein_id="HDV1988914.1"
                     /translation="MKRVITLFAVLLMGWSVNAWSFACKTANGTAIPIGGGSANVYVN
                     LAPAVNVGQNLVVDLSTQIFCHNDYPETITDYVTLQRGSAYGGVLSNFSGTVKYSGSS
                     YPFPTTSETPRVVYNSRTDKPWPVALYLTPVSSAGGVAIKAGSLIAVLILRQTNNYNS
                     DDFQFVWNIYANNDVVVPTGGCDVSARDVTVTLPDYPGSVPIPLTVYCAKSQNLGYYL
                     SGTTADAGNSIFTNTASFSPAQGVGVQLTRNGTIIPANNTVSLGAVGTSAVSLGLTAN
                     YARTGGQVTAGNVQSIIGVTFVYQ"
     gene            complement(7532..8035)
                     /gene="fimG"
                     /locus_tag="RHX21_003791"
     CDS             complement(7532..8035)
                     /gene="fimG"
                     /locus_tag="RHX21_003791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria minor subunit FimG"
                     /protein_id="HDV1988915.1"
                     /translation="MKWRKRGYLLAAILALASATIQAADVTITVNGKVVAKPCTVSTT
                     NATVDLGDLYSFSLMSAGAASAWHDVALELTNCPVGTSRVTASFSGAADSTGYYKNQG
                     TAQNIQLELQDDSGNTLNTGATKTVQVDDSSQSAHFPLQVRALTVNGGATQGTIQAVI
                     SITYTYS"
     gene            complement(8048..8578)
                     /gene="fimF"
                     /locus_tag="RHX21_003792"
     CDS             complement(8048..8578)
                     /gene="fimF"
                     /locus_tag="RHX21_003792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria minor subunit FimF"
                     /protein_id="HDV1988916.1"
                     /translation="MRNKPFYLLCAFLWLAVSHALAADSTITIRGYVRDNGCSVAAES
                     TNFTVDLMENAAKQFNNIGATTPVVPFRILLSPCGNAVSAVKVGFTGVADSHNANLLA
                     LENTVSAAAGLGIQLLNEQQNQIPLNAPSSAISWTTLTPGKPNTLNFYARLMATQVPV
                     TAGHINATATFTLEYQ"
     gene            complement(8588..11224)
                     /gene="fimD"
                     /locus_tag="RHX21_003793"
     CDS             complement(8588..11224)
                     /gene="fimD"
                     /locus_tag="RHX21_003793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial usher FimD"
                     /protein_id="HDV1988917.1"
                     /translation="MSYLNLRLYQRNTQCLHIRKHRLAGFFVRLFVACAFAAQAPLSS
                     AELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFNTGDSE
                     QGIVPCLTRAQLASMGLNMASVAGMNLLADDACVPLTTMVQDATAHLDVGQQRLNLTI
                     PQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIG
                     AWRLRDNTTWSYNSSDRSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGI
                     NFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTIND
                     IYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQEK
                     PRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLPD
                     DSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGV
                     IQVKPKFTDYYNLAYNKRVKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQAGL
                     NTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMS
                     HDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANI
                     GYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDTKVENQTGVRTD
                     WRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKL
                     LMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCV
                     ANYQLPPESQQQLLTQLSAECR"
     gene            complement(11291..12016)
                     /gene="fimC"
                     /locus_tag="RHX21_003794"
     CDS             complement(11291..12016)
                     /gene="fimC"
                     /locus_tag="RHX21_003794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418736.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria chaperone FimC"
                     /protein_id="HDV1988918.1"
                     /translation="MSNKNVNVRKSQEITFCLLAGILMFMAMMVAGRAEAGVALGATR
                     VIYPAGQKQVQLAVTNNDENSTYLIQSWVENADGVKDGRFIVTPPLFAMKGKKENTLR
                     ILDATNNQLPQDRESLFWMNVKAIPSMDKSKLTENTLQLAIISRIKLYYRPAKLALPP
                     DQAAEKLRFRRSANSLTLINPTPYYLTVTELNAGTRVLENALVPPMGESTVKLPSDAG
                     SNITYRTINDYGALTPKMTGVME"
     gene            complement(12053..12592)
                     /locus_tag="RHX21_003795"
     CDS             complement(12053..12592)
                     /locus_tag="RHX21_003795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418735.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDV1988919.1"
                     /translation="MKRKRLFLLASLLPMFALAGNKWNTTLPGGNMQFQGVIIAETCR
                     IEAGDKQMTVNMGQISSNRFHAVGEDSAPVPFVIHLRECSTVVSERVGVAFHGVADGK
                     NPDVLSVGEGPGIATNIGVALFDDEGNLVPINRPPANWKRLYSGSTSLHFIAKYRATG
                     RRVTGGIANAQAWFSLTYQ"
     gene            complement(12657..13205)
                     /gene="fimA"
                     /locus_tag="RHX21_003796"
     CDS             complement(12657..13205)
                     /gene="fimA"
                     /locus_tag="RHX21_003796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial major subunit FimA"
                     /protein_id="HDV1988920.1"
                     /translation="MKIKTLAIVVLSALSLSSTAALAAATTVNGGTVHFKGEVVNAAC
                     AVDAGSVDQTVQLGQVRTASLAQEGATSSAVGFNIQLNDCDTNVASKAAVAFLGTAID
                     ATRTDVLALQSSAAGSATNVGVQILDRTGNALTLDGATFSAQTTLNNGTNTIPFQARY
                     YAIGEATPGAANADATFKVQYQ"
BASE COUNT         3322 a         3488 c         3295 g         3492 t
ORIGIN      
        1 gtctatgcca ttaagcaatg cccttcagag tcaaattatt acagatgatc acttccttca
       61 tcatccaaaa gtcgacaatg agttaacacg taaatatgaa cgtgcacgcc tggatacgga
      121 aaatatctat cttctgcctc ttactcgtgg caataatcat aattacgatg gaaaaagcgt
      181 tgtcgaaatt agaaaacttg atattagtaa agagtcctgg ccatttaatt atgtgacaga
      241 aacatgcaga gaatccgatg gtattacaac aacaggacgt atgctctatc gaaacttgcg
      301 aatcacctca gctttagacg aaatatatgg tggtatatgt aaaaaggcgc atgctgccac
      361 agagttagca gaaggattac ggctaaattt atttatgaag agccctttcg ctcctgttga
      421 ggactataca gttcatgaaa taacattagg ccctggttgc aatgttccag gttacgccgg
      481 aaccacgata ggatatattt caacacttcc agtttctcag gcaaaaagat ggaccaatga
      541 gcagccaagg attgatatct atattgatca gataataact gtctcagggg tggcaaattc
      601 ttccggattc gcccttgccg cattacttaa tgctaatatt gaaatgggaa atgacccaat
      661 aattggtata gaagcctatc ctggtaccgc ggagatccat gcaaaaatgg gatataaagt
      721 tatccccggt gatgaagatg cgccactcaa acgcatgact ctgcaaccgt catctcttcc
      781 agaactgttt gaattaaaaa atggtgaatg gaattatatt ggtaaataac cactgagaag
      841 aatgagtgct aacattcagg ttatacagat agttaaacaa taccctgtaa tttagaaagt
      901 aatactcatt gcgacttctt aatttaagaa agcgcaagga acgtttaccc ttgcgcttat
      961 cataataagt caggcgtcga ctttatccag cggccatgaa tcaaacaaat agccgtcaaa
     1021 ataaatatcg tcaacgttcg agaattccag cagacgttgt ttaacgtttt ccagatgctg
     1081 ccacattgcc agcttcgccg ctcgagcatc ttttttgatt aacgcggcaa ggatctgttt
     1141 gtgatcgccc aaccactctt tgcgatacag gctgtcatcc agatggctgt gcaactggat
     1201 ccacatcgga ttgttttccc gccactgcca ggactgacgg aataactcca ccagcatgct
     1261 gttatgcgtt gcttcggcaa tggcgagatg gaactgcatg tcaccacttt cgctgctgcc
     1321 tggcgcgctg gaagcaagct cacgctcttc cagttgcaat gcctgacgca ttttgacgat
     1381 atcttcgcgg gtagcctgca gggcggcaaa ttccgcgatg ttactttcca gtaactgacg
     1441 cgcctgtaac agctcaaaag gaccagcatc attgcagacg ttggcatccg gactgtctgt
     1501 gttgtggctg cctgagctat caagaacata gataccggca ccccgacgca cttccaccag
     1561 ccctttgatc tccagcatga tcagcgcttc acgtaccacc gtccgcgtga catcaagcat
     1621 ttctgcaatt tcacgctccg gcggcagccg ttcgccagga ttgtacggcg tctttatgat
     1681 cagatcgcgg atcatcgccc cgacttcctg gtaaggtctt tgcgcagagg tggcagattt
     1741 catggtgttg tgtccgttag atgcggttaa tcaaattttt gccggatgcg gcgtgaatgc
     1801 cttatacggc ctacaacggg caattttacg gcacccgtta atctcaaact ataccattag
     1861 cactggaagt tggcacgtac aggtgggcaa aaaaacgaaa actggtcaac caaatatgcg
     1921 tttgattgac cagtaagtct gtagggtaat cagttagtta cagcgcagcc acacactcgc
     1981 gagcaccgcg ttcgcacagc tgctgatatg ccgtcgtcac cgcgccaaca aagtcggcat
     2041 tctgcggcag atcatcagca aagataccgc tcaggcccag cagcgctttc acgcggtctg
     2101 cgccctgata ctgcgcgttg atcttctgga actccgccag catcgggtca accacgtcaa
     2161 tggcattacc ctgctcatcc acgccctggg tgtaacgcat ccagccagcc acgcccagcg
     2221 ccagatgacg ccagctaccg ccgttttgca ggtgcagacg caccggatcc agcagacgct
     2281 gcggtaactt ctggctgccg tccatcgcaa tctgccaggt acggtgacgc agagacgggt
     2341 tgctgaaacg ctcgatcagc agcgtcgcat aggcgttcag gtctgtacct tccggcatcg
     2401 acagcgttgg cgcttgttcc tgcatcatca gggcaaaggc cgctttgcga taatccggat
     2461 tagtcatggt gtcggcaata gtttcatagc cgccgaggta accgaggtac gccaggaaag
     2521 agtggctgcc gttcagcata cgcagcttca tcatttcgaa cggcacaaca tccgcaacaa
     2581 actgcgcgcc gactttatcc cagtccggac gaccattaac gaagttatct tcaattaccc
     2641 actgacggaa cggttcgcag gcaatggcgc acgggtcgta aacacccagc tggtcagcaa
     2701 tttcctgtaa ggtttctggc gtcgccgccg gaacgatgcg gtcaaccatg gtgcacggga
     2761 aggtgacgtt ctcttcaatc catgccgcca gctgtggatc acgcgcctga gccagcccca
     2821 gaaccgcgac cttcgccaca tgaccgtttt cacgcacgtt gtcgcaggac atcaccgtaa
     2881 acgctttcag ccctttttca cgacgcagac gcaaggcttc gacgatgtaa ccaatcgcgg
     2941 acttcggcgc agtcgggttt tccagatcgt gcttaatcag cggattattg agatccagct
     3001 gaccgcttgc cgcatcggcg caataacctt tctctgtgac cgtcagggag acaatcgccg
     3061 tctgcggacg cgccatcgcg ttgagaatac cttcacaacc gtcgatttcc ggatgcaggg
     3121 cttctttcat cgaaccgata attttcagct cggtgctttc tgcgcctttt tccgccacgg
     3181 tgtacagcag ttgctgtttt ttcaggtttt cgatcagcac gcggtcgtta cctggcatca
     3241 ggttaacttc gcagataccc cagtcgctgt cggtgctttc cagcagatga tgggtgtaca
     3301 gcgcctggtg cgcgcggtga aacgcaccgc aaccgagatg cacaatgcgt gattccagac
     3361 gagaatgatc ccatgacggg cgggcaaccg gcagattgct gtcaacaata gtagtcatcg
     3421 taaactccag aatccgtctt cagagagtga cggcaaggaa gaaggaaccg gcacggcgcg
     3481 cagccatgcc ggtggatatt aacggctaaa gaaagcgcgc tggatcgcca gttcgacacc
     3541 gcgaacttcg gccaggcctt tcagacgacc aattgcggag taacctgggt tggttttctt
     3601 cttcaggtcg tccagcatct gatgaccgtg gtccggacgc atcgggatca ggtcttcttt
     3661 gccttccgct ttacgacggt gttcttcttc aactatcgct ttcaccactt cgtacatatc
     3721 aacgtcaccg ttcaggtgcg ccgcttcgtg gaaggttttc gggttatctt cacgcatggt
     3781 ggagcgcaga tgggtgaagt aaatacgcgg accaaactgc ttgatcatat caaccagatc
     3841 gttgtcagcg cgcacgccgt aggaaccggt gcacatggtg aaaccgttcg ccatgctgtt
     3901 tacggtatca accatccact gcatatcttc aatggtggaa acgatacgcg gcaggccgag
     3961 gatcgggcgc ggcggatcgt ccgggtgaac cgccatacgc acgccaactt cttcggcaac
     4021 cggaataatg gctttcagga agacagcaaa gttttcgcgc agtttggctt tgtcgatatc
     4081 tttgtacagc tccaggtgct tacggaactg gtcgagggtg tagccttctt ccgcgcccgg
     4141 cagaccggca atgatgttac gggtcagacg cgctttgtct tcgtcgctca tagtggcgaa
     4201 gcgttcagcg gcctgagcaa tttcttcttc ggtgtaatcc gcttccgcac ctggacgctt
     4261 caggatatgc atttcaaatg cagcgaattc gatctggtcg aagcgcagag ctttggagcc
     4321 gtccggcagc acgtattcga ggtcagtacg ggtccagtcg agcaccggca tgaagttgta
     4381 gcacacggtg cgaatgccgc actgcgccag gttgcgcagg gtctgctgat agttagcgat
     4441 ccactgctcg tagttgccag tgtgggtttt gatatcttcg tgaattggca cgctttctac
     4501 gacagaccac accaggcctg cgtcttcaac gatcgccttg cgtttgagga tctcttctac
     4561 ggaccatact tcgccgttcg ggatatggtg cagcgcggta accacgccag ttgcgcccgc
     4621 ctgacggaca tcagctaaag aaaccggatc gtttgggccg taccagcgcc aggtctgttc
     4681 catgattttt cctctttcac atagtgggtt ccacagcaaa gagacgcgga accccggagt
     4741 tgtttaggta tccggatgaa caaccagacc gcagccgtgg cgttgcatcg gatgagatgg
     4801 cgtataagtt ctaccttttg gtaagacatg tcaaccagaa atctgaaatt ggttaaccac
     4861 atcacaagaa tttcactctc acggttgttg ctgcaaattg cagcaaaggg taatcgatgg
     4921 ttattgatca gaggatgtga cattcatcgc aacaatggtt gaccaattta cataacatgt
     4981 cgcccaaaat aacaacggtt caaccaggta aggtaaaacg ttatgcatgt gcttaacatt
     5041 ctctgggtgg tattcggcat tggcctgatg ctggtactga atttgaagtt caaaatcaat
     5101 tcaatggtgg ctttgctagt ggcggcgctg tccgtcggga tgctggcggg catggatttg
     5161 atgtcgctgc tgcacaccat gaaagcgggc ttcggcaaca cgctggggga actggctatc
     5221 atcgtggtgt tcggtgcggt catcggtaaa ttgatggtcg actccggcgc ggctcaccag
     5281 atagcgcata cgctgctggc gcgtctcggt ctgcgctatg tacagctgtc ggtgattatc
     5341 atcggcctga ttttcggtct ggcgatgttc tatgaagtgg cctttatcat gttagcgccg
     5401 ctggttatag tgattgccgc cgaagctaaa attccgttcc tgaaactggc gatcccggca
     5461 gtagcagcag ccactaccgc acattcactg ttcccaccgc agccgggtcc ggtggcgctg
     5521 gtgaatgctt atggcgcgga tatggggatg gtttatatct atggcgtact ggtgacgatc
     5581 ccaagtgtca tctgcgcagg tctgatcctg ccgaagttcc tcggcaatct tgagcgccca
     5641 acgccatcat tcctgaaagc agatcaaccg gtagatatga ataatctgcc ctctttcggc
     5701 gtttcgattc tggtgccgct gatcccggcg atcattatga tctctaccac catcgccaat
     5761 atctggctgg taaaagatac ccctgcctgg gaagtggtta actttatcgg ttcctcgccg
     5821 attgcaatgt ttattgcgat ggtggttgca ttcgtactct tcggcaccgc gcgcgggcac
     5881 gatatgcagt gggtgatgaa cgcttttgaa agcgcggtga agagcattgc aatggtgatt
     5941 ctgatcatcg gtgcgggtgg cgtgctgaag cagaccatca tcgacaccgg cattggcgac
     6001 accatcggca tgttgatgtc ccacggcaat atctcgccct acatcatggc atggctgatc
     6061 accgtactga ttcgtctggc gacgggtcag ggtgtcgttt cggcgatgac cgctgccggg
     6121 attatcagtg cagcaatcct tgatccagca actggtcagc tggttggcgt gaatccggcg
     6181 ctgctggtac tggcgacggc tgcgggttcc aacaccctca cccacattaa cgatgcatct
     6241 ttctggttgt tcaaaggtta ctttgacctg tcagtaaaag acacgttgaa aacctggggt
     6301 ctgctggagc tggtcaactc cgtggttggg ctgattattg tgctgattat tagcatggta
     6361 gcgtaaaaga acaccagagc ctgccattgg caggctcaga ctgatgacta aagtctaaaa
     6421 atgtgcccgg acagtcccct cgcccctccg gggagagggt tagggtgagg ggaacagacc
     6481 agcaaagtgc gctttgtgta tgccagatgc gacgctgacg cgtcttatct ggcctacaaa
     6541 gggctaacgt gcaggttttt agcttcaggt aatattgcgt acctgcatta gcaatgccct
     6601 gtgatttctt tattgataaa caaaagtcac gccaataatc gattgcacat tccctgcagt
     6661 cacctgccct ccggtacgtg cgtaatttgc cgttaatccc agacttaccg ccgaagtccc
     6721 cactgctcct aacgataccg tgttattcgc tggaataatc gtaccgttgc gcgtcaactg
     6781 tacgccgacg ccctgtgctg gtgaaaacga ggcggtattg gtgaaaatcg agttgcccgc
     6841 atctgcggtt gtgccggaga ggtaataccc caggttttgg cttttcgcac aataaacggt
     6901 aagaggaatc ggcactgaac cagggtagtc cggcagagta acggtgacat cacgagcaga
     6961 aacatcgcag ccgccagtag gcaccaccac atcattattg gcgtaaatat tccacacaaa
     7021 ctggaaatca tcgctgttat agttgttggt ctgtcgcaaa ataagcacgg caattaatga
     7081 gccagcttta atcgccaccc cgcccgcact gctcacaggc gtcaaataaa gcgccaccgg
     7141 ccacggctta tccgttctcg aattataaac aacgcgcggc gtttcactgg tggtcggaaa
     7201 tggatagcta ctgccactat attttacggt cccggaaaaa ttagataaca cgccgccata
     7261 agccgaacct cgttgcagtg tgacatagtc tgtaatggtt tccgggtaat cgttatggca
     7321 aaagatttgc gtcgaaagat ctacgaccag gttttgcccc acattcacgg cgggcgcaag
     7381 gtttacataa acattggcgc tgccaccgcc aatagggata gcggtgccat tggcggtttt
     7441 acaggcgaat gaccaggcat ttaccgacca gcccatcagc agtacagcaa acagggtaat
     7501 aactcgtttc attacaatca tctcttcggc ttcagctgta ggtataggtg atgctaatca
     7561 ctgcctgaat ggttccctga gtggctccgc catttaccgt caatgctctg acctgtaacg
     7621 ggaagtgcgc tgattgtgag gaatcatcca cctgaactgt tttggttgcg ccagtattca
     7681 atgtgttgcc actgtcatcc tgtagctcta actggatgtt ttgcgcggtc ccctggtttt
     7741 tataatatcc ggtactgtcg gctgccccgc tgaagctggc ggtgaccctc gacgttccca
     7801 ccggacaatt agtcaactca agcgcaacat catgccaggc cgatgccgcc ccggcagaca
     7861 tcagactgaa agaataaaga tcgccgagat ctacggttgc attggtggtg gaaaccgtgc
     7921 acggtttggc gacgacctta ccgttcaccg tgatggtgac atcggctgcc tgtatcgtcg
     7981 cacttgcgag cgccaatatt gccgccaata aatacccacg tttgcgccat ttcatgagca
     8041 tctccagtta ctgatattca agagtgaagg tagccgtggc attgatatgc cccgcagtga
     8101 caggcacctg tgtcgccatt agccgggcgt aaaaattcag cgtatttggt ttacccggcg
     8161 tcagggtcgt ccacgaaatc gcggacgatg gggcattaag gggtatctga ttttgttgct
     8221 cattcagaag ctgtattccc agtcccgcag ccgctgacac cgtattttca agtgcaagca
     8281 ggttggcatt gtggctatct gcaacgccgg taaacccaac ttttacggca gaaacggcat
     8341 taccacaggg tgacagcaaa atacgaaatg gaacgacagg agtcgtcgcg ccaatgttgt
     8401 taaattgctt cgccgcgttt tccatcagat caacagtaaa attggttgat tcagcggcca
     8461 cactacagcc gttatctctg acatagccgc ggatagtaat cgtgctatcc gcagccaaag
     8521 cgtgacttac cgccagccac aaaaaagcgc acagaagata aaaaggtttg tttctcatca
     8581 cgccccctta acgacattca gctgatagct gggttaataa ctgctgctga ctctctggtg
     8641 gcagttgata attggcgaca cagtgagcat tttcctcttc tccccatttc acctgaactt
     8701 ttcccgctaa aggcattccg ctgaggtaaa cctgaccatt atccgcaaca atgccgctac
     8761 tctggctact ctctgatgtc accatcgccc caaacggcag cggcttatta ttgtgggtta
     8821 gcgtcatgag cagttttatc ccaacgcgcg ctttaaactc tgctcgcacg atcgccccac
     8881 gagtgggaac aacgttagcg accgcgttat ctaaatcgac gttatcagcc agggtattgg
     8941 tatccagcgc cactctgttt tcccgatatt cagtggcata aggcagcacg gcataaccgc
     9001 gccagtcggt acgcactcct gtctggtttt cgacttttgt atcttttgcg ccaggcgctt
     9061 taacaagtac caccgtatcg tttaacggct gccccagcgt tacgccattg gcatgagcca
     9121 ataccccacc gctgactccg taatagagct gcttaatatc atcgctatgg ctgtaaccga
     9181 tgttggcatt gccgtaacca ccgcgataat tcagcgtggc gtagcctgtg cttccgctat
     9241 taccatcgcc tcccccggca tagccggttt gcacgctata gctgaggttg ttgtcttcca
     9301 gcaacgtacc gtatacacca gccagattgg tcatccgacc gttgagatcg tgtgacatgc
     9361 tgtagctggc actggcatgt cgccactgag atttactatc agaacgcagc cagtggctga
     9421 aaggaatatt gacgttaagc gctaacatct gatcccgtcc tttttgccag gcgtttttcg
     9481 tcaggctata gctgagcgtc cagttgatat cttcgaacgc agtatttaaa ccagcctgga
     9541 attgctcatc gacattactc gtaccccaat aagtttgatg gctaccactc aaatacagtg
     9601 ttgatgtgcg cccgagttgc tgagtaacgg tgagctgtaa tttcacgcgt ttgttataag
     9661 cgagattgta atagtcggta aattttggct taacctgaat aacaccatcc tgtgtttcga
     9721 tgttgtagcc attcattcga ctgtatgttg tatcagcgaa attaaaatat ccgctggtcg
     9781 aataacggta acccactaac tgaatattcg tgcctgactc attgagcgat ttgttataga
     9841 gaaaacgcac cgattgtccg tcatgctgac tgtcatcggg aagtgtggaa ttagcctgcg
     9901 tcatatccac agacagagcg cccagtgctc ccatgttttt cccgataccg aaattaaaag
     9961 cacgataacg atccgccagt tgcgttccac catatattgt ccagccagcc ggaaggccgt
    10021 ggagtaatgt actctggaaa aagcggggtt tttcctgctg cgcatttcca ctacggtatt
    10081 ctcctgccgt aatggaataa cgagtatgtc cttcccgttg caaaagcggg actgacgaat
    10141 agggtacggt aaagatctgc gtgctgccgt cagcctcttt aatcgttacc tgcaagtcac
    10201 cactattacc tgcggcatag atatcgttga tggtaaaagg ccccggcggc accgtactat
    10261 tataaatgtc atacccattt tgtttaatag tgacctgtgc agtaccacga gcaataccgt
    10321 ggatcaccgg ggcaaatcct ctttgactat cgggtaacat attgtcatct gaggccaatt
    10381 gtgcgccgcg aaagttaata ccatcgaaaa tatcgccctg agtataacca tcacccagcg
    10441 tcagccggga acgtaacggt attatgtctc gctcaagcca ggtattgata tgctgccatt
    10501 tatttttgct acctgatgat ctgtcgctac tgttataact ccaggtggta ttgtcgcgta
    10561 aacgccacgc accaatattt aacccactct gtaggtttaa atatgcataa tggctgttac
    10621 ccccaatccg attctgtaca ctatttccgc tgaaattata attgagcaat ccggcattaa
    10681 taccgggatc ccataactca ggaggaatat aaccacgcgc gcgattactc ataaatgcct
    10741 gagggatcgt caggttgagt cgctgctgac caacatctaa atgcgcagta gcgtcctgga
    10801 ccattgtggt taatggcaca caggcatcat ccgccagcag attcataccg gcgacagaag
    10861 ccatattcag ccccatactg gcgagttgcg cgcgtgtcag gcagggaaca atcccttgtt
    10921 cactgtcgcc cgtattaaat gtgacatcac gcgttgccat ataaccatta ttcaaataga
    10981 tatcgacgcg atacgtccct ggcggtaatt cttgtccatt ttcaaaacgc gataaatcag
    11041 ccacagcctg gggatcatcc gctaaaaagc gcgggttaaa atagagttcg gcagatgaca
    11101 aaggtgcctg tgcggcaaaa gcacaggcaa caaagagccg gacaaaaaaa ccagccaaac
    11161 gatgcttacg aatatgcaag cattgtgtgt ttcgctggta aagtcttaaa ttcagatatg
    11221 acattattcc tccggtttaa aatcacccgg cagtcaattc tttttattca ggcgaaaaat
    11281 tccccctgcg ttattccatt acgcccgtca ttttgggggt aagtgcgcca taatcattta
    11341 ttgttcggta agtaatattg cttcctgcat cagaaggcaa tttaaccgtg ctttcgccca
    11401 ttggaggcac caatgcattt tcaagaaccc gggttccggc attcaactct gttaccgtca
    11461 ggtaataggg tgtcgggtta atcagcgtca gagaattcgc gctacgacga aatcttaatt
    11521 tttctgcggc ctgatcgggt ggcaacgcta atttagccgg acgatagtac agtttaatgc
    11581 ggctgataat tgcgagctgt agcgtattct cagtcaattt tgatttatcc attgacggaa
    11641 tcgctttaac gttcatccag aataaacttt cccgatcctg tggcaattgg ttattggttg
    11701 catcaagaat acgtaaggta ttctcttttt ttcccttcat cgcaaacaga ggtggcgtca
    11761 caataaaacg accatccttt acaccatcgg cattttccac ccatgattga attaaatagg
    11821 tgctattttc atcattattt gtaacggcaa gttgcacttg tttttgccct gccggataaa
    11881 ttacgcgagt cgcacctaag gccactcccg cttcagcgcg tccggcaacc atcattgcca
    11941 tgaacatcag gatacctgcc agcaagcaga atgttatttc ctgcgatttc cttacattga
    12001 cgtttttatt actcactgtc ctgttcctgt tatcacatta tctgctgaac aattactgat
    12061 aggttaaaga gaaccaggcc tgggcattgg cgatgccgcc agtaacccga cgcccggtag
    12121 cacgatattt ggcgatgaaa tgtagcgaag tagagcctga gtaaagccgt ttccagtttg
    12181 ctggaggacg attaatcggt acgaggttgc cttcatcatc aaacaacgct acgccaatat
    12241 tggtggctat ccctggcccc tctcccacgg aaagcacatc cggattttta ccatccgcga
    12301 caccgtgaaa cgccacacct acacgttcac tcaccaccgt gctacattcc cgtaaatgaa
    12361 taacaaaagg caccggtgcg ctatcttccc ctaccgcatg aaaccggtta ctgctgattt
    12421 gccccatatt gaccgtcatt tgtttatcac cggcttcaat ccggcaagtt tccgcaataa
    12481 tgacgccctg aaattgcata tttccgccgg gcaacgtggt attccattta tttccggcca
    12541 gagcaaacat tggcagtaac gacgctaata gaaataatct cttccttttc atcgttattt
    12601 ttatcgcaca agggtgggca tccctgcccg taatgacgtc cctgaacctg ggtaggttat
    12661 tgatactgaa ccttgaaggt cgcatccgca ttagcagcac ccggggttgc ctcgccgatt
    12721 gcataataac gcgcctggaa cggaatggtg ttggtaccgt tattcagggt tgtttgtgca
    12781 ctaaatgtcg caccgtccag cgtcagagca ttgcctgttc tgtccaggat ctgcacgcca
    12841 acgtttgttg cactacctgc agcagaactc tgcagagcca gtacatcagt acgcgtagca
    12901 tcaattgctg tacctaaaaa ggcaacagcg gctttagatg caacattggt atcgcaatca
    12961 ttcagctgaa tgttaaaacc gacagcagaa ctggttgctc cttcctgtgc cagcgatgcg
    13021 gtacgaacct gtcctaactg aacggtttga tcaacagagc ctgcatcaac tgcgcaagcg
    13081 gcgttaacaa cttccccttt aaagtgaacg gtcccaccat taaccgtcgt ggcagcggcc
    13141 agagccgctg tagaactgag ggacagagcc gacagaacaa cgattgccag agttttaatt
    13201 ttcatgctgc tttcctttaa aaaaactatt tctaaatcga catgggtagt cgttctgtac
    13261 actttgtttt gtcaacgagt ttgactgcca acactgcaca gttttccccc aaaagatgaa
    13321 acatttgggg ccattttgac tcatagagga aagcatcgcg cacaaacttt ttcagtttat
    13381 ttgttggctt gatattctgc agttatcttt atttatagat ttttatattg catgaggtgg
    13441 tttttggaga gaagaatgag gaagatgcgt cgagccacag aaacgttagc tttacattta
    13501 gcggaggtga tgtgaaatta atttacagga gaaataattt acatatcaaa cagttagatg
    13561 ctttttgtcg ttttttaata tttttatgct tgagaaa
//
LOCUS       DAPGUL010000122        13251 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.124, whole genome shotgun sequence.
ACCESSION   DAPGUL010000122 DAPGUL010000000
VERSION     DAPGUL010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13251)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13251)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13251
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.124"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(92..1342)
                     /gene="icd"
                     /locus_tag="RHX21_003797"
     CDS             complement(92..1342)
                     /gene="icd"
                     /locus_tag="RHX21_003797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent isocitrate dehydrogenase"
                     /protein_id="HDV1988921.1"
                     /translation="MESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPA
                     MLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGP
                     LTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIY
                     AGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAI
                     ANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIV
                     IKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGANIGDECAL
                     FEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAINAKTVTYD
                     FERLMEGAKLLKCSEFGDAIIKNM"
     gene            1514..2167
                     /gene="rluE"
                     /locus_tag="RHX21_003798"
     CDS             1514..2167
                     /gene="rluE"
                     /locus_tag="RHX21_003798"
                     /EC_number="5.4.99.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415653.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2457) synthase RluE"
                     /protein_id="HDV1988922.1"
                     /translation="MRQFIISENTMQKTSFRNHQVKRFSSQRSTRRKPENQPTRVILF
                     NKPYDVLPQFTDEAGRKTLKEFIPVQGVYAAGRLDRDSEGLLVLTNNGALQARLTQPG
                     KRTGKIYYVQVEGIPTQDALEALRNGVTLNDGPTLPAGAELVDEPAWLWPRNPPIRER
                     KSIPTSWLKITLYEGRNRQVRRMTAHVGFPTLRLIRYAMGDYSLDNLANGEWREVTD"
     gene            2177..2638
                     /gene="nudJ"
                     /locus_tag="RHX21_003799"
     CDS             2177..2638
                     /gene="nudJ"
                     /locus_tag="RHX21_003799"
                     /EC_number="3.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase NudJ"
                     /protein_id="HDV1988923.1"
                     /translation="MFKPHVTVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETL
                     VEAAARELWEETGISAQPQHFIRMHQWIAPDKTPFLRFLFAIELEQICPTQPHDSDID
                     CCRWVSAEEILQASNLRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTKGVI"
     gene            2692..3798
                     /gene="mnmA"
                     /locus_tag="RHX21_003800"
     CDS             2692..3798
                     /gene="mnmA"
                     /locus_tag="RHX21_003800"
                     /EC_number="2.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415651.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HDV1988924.1"
                     /translation="MSETAKKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDD
                     GEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLAEYKAGRTPNPDILC
                     NKEIKFKAFLEFAAEDLGADYIATGHYVRRADVDGKSRLLRGLDSNKDQSYFLYTLSH
                     EQIAQSLFPVGELEKPQVRKIAEDLGLVTAKKKDSTGICFIGERKFREFLGRYLPAQP
                     GKIITVDGDEIGEHQGLMYHTLGQRKGLGIGGTKEGTEEPWYVVDKDVENNILVVAQG
                     HEHPRLMSVGLIAQQLHWVDREPFTGTMRCTVKTRYRQTDIPCTVKALDDDRIEVIFD
                     EPVAAVTPGQSAVFYNGEVCLGGGIIEQRLPLPV"
     gene            3834..4475
                     /gene="hflD"
                     /locus_tag="RHX21_003801"
     CDS             3834..4475
                     /gene="hflD"
                     /locus_tag="RHX21_003801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high frequency lysogenization protein HflD"
                     /protein_id="HDV1988925.1"
                     /translation="MAKNYYDITLALAGICQSARLVQQLAHQGHCDADALHVSLNSII
                     DMNPSSTLAVFGGSEANLRVGLETLLGVLNASSRQGLNAELTRYTLSLMVLERKLSSA
                     KGALDTLGNRINGLQRQLEHFDLQSETLMSAMAAIYVDVISPLGPRIQVTGSPAVLQS
                     PQVQAKVRATLLAGIRAAVLWHQVGGGRLQLMFSRNRLTTQAKQILAHLTPEL"
     gene            4479..5849
                     /gene="purB"
                     /locus_tag="RHX21_003802"
     CDS             4479..5849
                     /gene="purB"
                     /locus_tag="RHX21_003802"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HDV1988926.1"
                     /translation="MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWL
                     QKLAAHAAIKEVPAFAADAIGYLDAIVANFSEEDAARIKTIERTTNHDVKAVEYFLKE
                     KVAEIPELHAVSEFIHFACTSEDINNLSHALMLKTARDEVILPYWLQLIDGIKDLAVQ
                     YRDIPLLSRTHGQPATPSTIGKEMANVAYRMERQYRQLNQVEILGKINGAVGNYNAHI
                     AAYPEVDWHQFSEEFVTSLGIQWNPYTTQIEPHDYIAELFDCVARFNTILIDFDRDVW
                     GYIALNHFKQKTIAGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQ
                     RDLTDSTVLRNLGVGIGYALIAYQSTLKGVSKLEVNRDHLLDELDHNWEVLAEPIQTV
                     MRRYGIEKPYEKLKELTRGKRVDAEGMKQFIDGLALPEEEKARLKAMTPANYIGRAIT
                     MVDELK"
     gene            6017..6688
                     /gene="phoP"
                     /locus_tag="RHX21_003803"
     CDS             6017..6688
                     /gene="phoP"
                     /locus_tag="RHX21_003803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator PhoP"
                     /protein_id="HDV1988927.1"
                     /translation="MRVLVVEDNALLRHHLKVQIQDAGHQVDDAEDAKEADYYLNEHL
                     PDIAIVDLGLPDEDGLSLIRRWRSNDVSLPILVLTARESWQDKVEVLSAGADDYVTKP
                     FHIEEVMARMQALMRRNSGLASQVISLPPFQVDLSRRELSINDEVIKLTAFEYTIMET
                     LIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPQEVITTVRGQGY
                     LFELR"
     gene            6688..8148
                     /gene="phoQ"
                     /locus_tag="RHX21_003804"
     CDS             6688..8148
                     /gene="phoQ"
                     /locus_tag="RHX21_003804"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PhoQ"
                     /protein_id="HDV1988928.1"
                     /translation="MKKLLRLFFPLSLRVRFLLATAAVVLVLSLAYGMVALIGYSVSF
                     DKTTFRLLRGESNLFYTLAKWENNKLHVELPENIDKQSPTMTLIYDENGQLLWAQRDV
                     PWLMKMIQPDWLKSNGFHEIEADVNDTSLLLSGDHSIQQQLQEVREDDDDAEMTHSVA
                     VNVYPATSRMPKLTIVVVDTIPVELKSSYMVWSWFIYVLSANLLLVIPLLWVAAWWSL
                     RPIEALAKEVRELEEHNRELLNPATTRELTSLVRNLNRLLKSERERYDKYRTTLTDLT
                     HSLKTPLAVLQSTLRSLRSEKMSVSDAEPVMLEQISRISQQIGYYLHRASMRGGTLLS
                     RELHPVAPLLDNLTSALNKVYQRKGVNISLDISPEISFVGEQNDFVEVMGNVLDNACK
                     YCLEFVEISARQTDEHLYIVVEDDGPGIPLSKREVIFDRGQRVDTLRPGQGVGLAVAR
                     EITEQYEGKIVAGESMLGGARMEVIFGRQHSAPKDE"
     gene            8224..9345
                     /gene="roxA"
                     /locus_tag="RHX21_003805"
                     /gene_synonym="ycfD"
     CDS             8224..9345
                     /gene="roxA"
                     /locus_tag="RHX21_003805"
                     /gene_synonym="ycfD"
                     /EC_number="1.14.11.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309600.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[50S ribosomal protein L16]-arginine
                     3-hydroxylase"
                     /protein_id="HDV1988929.1"
                     /translation="MEYQLTLNWPDFLERHWQKRPVVLKRGFNNFIDPISPDELAGLA
                     MESEVDSRLVSHQDGKWQVSHGPFESYDHLGETNWSLLVQAVNHWHEPTAALMRPFRE
                     LPDWRIDDLMISFSVPGGGVGPHLDQYDVFIIQGTGRRRWRVGEKLQMKQHCPHPDLL
                     QVDPFEAIIDEELEPGDILYIPPGFPHEGYALENAMNYSVGFRAPNTRELISGFADYV
                     LQRELGGNYYSDPDVPPRAHPADVLPQEMDKLREMMLELINQPEHFKQWFGEFISQSR
                     HELDIAPPEPPYQPDEIYDALKQGDVLVRLGGLRVLRIGDDVYANGEKIDSPHRPALD
                     ALASNIALTAENFGDALEDPSFLAMLAALVNSGYWFFEG"
     gene            complement(9491..10720)
                     /gene="pepT"
                     /locus_tag="RHX21_003806"
     CDS             complement(9491..10720)
                     /gene="pepT"
                     /locus_tag="RHX21_003806"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HDV1988930.1"
                     /translation="MDKLLERFLNYVSLDTQSKAGVRQVPSTEGQWKLLHLLKEQLEE
                     MGLINVTLSEKGTLMATLPANVPGNIPAIGFISHVDTSPDCSGKNVNPQIVENYRGGD
                     IALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGIAEIMTALAVLQQKNI
                     PHGDIRVAFTPDEEVGKGAKHFDVDAFDARWAYTVDGGGVGELEFENFNAASVNIKIV
                     GNNVHPGTAKGVMVNALSLAARIHAEVPADESPEMTEGYEGFYHLASMKGTVERADMH
                     YIIRDFDRKQFEARKRKMMEIAKKVGKGLHPDCYIELVIEDSYYNMREKVVEHPHILD
                     IAQQAMRDCDIEPELKPIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVTLEGMEK
                     AVQVIVRIAELTAQRKS"
     gene            10970..12106
                     /gene="potA"
                     /locus_tag="RHX21_003807"
     CDS             10970..12106
                     /gene="potA"
                     /locus_tag="RHX21_003807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     ATP-binding protein PotA"
                     /protein_id="HDV1988931.1"
                     /translation="MGQSKKLNKQPSSLSPLVQLAGIRKCFDGKEVIPQLDLTINNGE
                     FLTLLGPSGCGKTTVLRLIAGLETVDSGRIMLDNEDITHVPAENRYVNTVFQSYALFP
                     HMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLETFAQRKPHQLSGGQQQRVAIAR
                     AVVNKPRLLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRI
                     VVMRDGRIEQDGTPREIYEEPKNLFVAGFIGEINMFNATVIERLDEQRVRANVEGREC
                     NIYVNFAVEPGQKLHVLLRPEDLRVEEINDDNHAEGLIGYVRERNYKGMTLESVVELE
                     NGKMVMVSEFFNEDDPDFDHSLDQKMAINWVESWEVVLADEEHK"
     gene            12090..12953
                     /gene="potB"
                     /locus_tag="RHX21_003808"
     CDS             12090..12953
                     /gene="potB"
                     /locus_tag="RHX21_003808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309597.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter permease
                     PotB"
                     /protein_id="HDV1988932.1"
                     /translation="MKNTSKFQNVVIVTIVGWLVLFVFLPNLMIIGTSFLTRDDASFV
                     KMVFTLDNYTRLLDPLYFEVLLHSLNMALIATLACLVLGYPFAWFLAKLPHKVRPLLL
                     FLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVIDTPIRIMFTPSAVIIGLVYI
                     LLPFMVMPLYSSIEKLDKPLLEAARDLGASKLQTFIRIIIPLTMPGIIAGCLLVMLPA
                     MGLFYVSDLMGGAKNLLIGNVIKVQFLNIRDWPFGAATSITLTIVMGLMLLVYWRASR
                     LLNKKVSELDD"
     gene            complement(13186..>13251)
                     /locus_tag="RHX21_003809"
     CDS             complement(13186..>13251)
                     /locus_tag="RHX21_003809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001387760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HDV1988933.1"
                     /translation="LLNRVDTSTAPDIEWPTSPAE"
BASE COUNT         3235 a         3372 c         3338 g         3306 t
ORIGIN      
        1 taaatatgct cgatatgcta ttaataatac ctacataaat aaaacaacgg gcgtgttata
       61 cgcccgttgc aatattaaac acatgtagtg attacatgtt cttgatgatc gcatcaccaa
      121 attctgaaca tttcagcagt ttagcgcctt ccatcagacg ctcgaagtca taggttacgg
      181 tcttcgcatt gattgcgcct tccatacctt taacaatcag gtctgcggct tcagtccagc
      241 ccatatggcg taacatcatc tcagcggaga gaataataga gccagggttt actttgtcct
      301 gaccggcgta tttcggcgca gtaccgtggg tggcttcaaa cagggcgcat tcgtcaccga
      361 tgtttgctcc aggggcgata ccgataccgc caacctgcgc tgccagagcg tcagaaatgt
      421 agtcaccatt caggttcata caggcgataa catcatattc agccggacgc agcaggatct
      481 gttgcaggaa tgcatcagca atcacgtctt taatgacgat ctctttgccg gtgttcgggt
      541 ttttaacttt cagccacggg ccgccgtcga tcagttcacc gccaaactct tcacgcgcca
      601 gctggtagcc ccaatcttta aacgcgcctt cggtgaactt catgatgttg cctttgtgca
      661 ccagagtcac agagtcacga tcgttagcaa ttgcgtattc gatcgctgca cgaaccagac
      721 gtttggtgcc ttcttccgaa cacggcttaa taccgatacc acaatgttcc gggaagcgaa
      781 ttttcttcac ccccatctct tcacgcagga atttaatcac tttctcggcg tcggcagagt
      841 ctgctttcca ttcgataccc gcataaatgt cttccgagtt ttcacggaag ataaccatat
      901 cggtcagttc agggtgttta accgggcttg gagtgccttg atagtaacgt accggacgca
      961 ggcagatgta gagatccagt tcctggcgca gggcaacgtt cagagagcga ataccgccac
     1021 caacaggagt ggtcagcgga cctttaatgg caacgcgata ttcacgaatc agatcaagag
     1081 tttcagcagg cagccagacg tcctgaccat aaacctgtgt ggatttttca ccggtgtaaa
     1141 tttccatcca ggagatttta cgctcgcctt tataggcttt ctcgactgca gcgtcgacca
     1201 ctttcagcat ggctggggtt acatctacac cgattccatc accttcaatg taagggataa
     1261 tcggattttc aggaacgttg agtttgccgt tttgcagggt gatcttcttg ccttgtgccg
     1321 gaacaactac tttactttcc attcacctct ccttcgagcg ctactggttt gctcgtctgc
     1381 caccacgttg catatgcgtt tgcgtcctgc gatacggatg ctttagagca attttttgtt
     1441 aatgatttgt aattggcttg tcaatactac cctattgttt gccgtcatga aagatgcgcg
     1501 ttattaggct ataatgcggc aattcataat ctctgaaaat accatgcaaa aaacttcttt
     1561 tagaaatcac caggttaagc gattcagctc gcaacgttct accaggcgta aacctgaaaa
     1621 ccagcccacg cgtgtgatcc tgttcaataa accctacgat gttcttccgc agttcaccga
     1681 tgaagccgga cgcaaaacat taaaagaatt catcccggtt cagggcgttt atgcagcagg
     1741 tcgtcttgac cgcgatagcg aagggttact ggtgctgacc aataacggcg cgttgcaggc
     1801 gcgtttaacc cagccgggca aacgcaccgg gaaaatctat tatgtgcagg tggaaggtat
     1861 tcccacacaa gacgcacttg aagccttgcg caatggcgta accttaaatg atggccctac
     1921 cctgcccgca ggcgcggagc tggttgacga acccgcgtgg ttatggccgc ggaatccacc
     1981 aattcgtgaa cgcaaaagta ttcccaccag ctggctgaag atcaccttat atgaaggacg
     2041 taatcgccag gtgcgccgca tgaccgccca tgttggtttc cccacgctgc gactgattcg
     2101 ctatgcgatg ggagattact ctttggataa tcttgccaat ggcgaatggc gagaagtgac
     2161 agattaagga tgcaaaatgt ttaaaccgca cgttaccgtt gcttgcgtgg tgcacgcaga
     2221 aggcaaattt ttagtcgttg aagagacgat taatggtaaa gcgttatgga accaacctgc
     2281 cgggcatctg gaagccgatg aaaccttagt ggaagccgcc gcccgtgaac tgtgggaaga
     2341 aaccggcatc agcgcgcagc cgcaacactt tattcgtatg catcagtgga ttgcgccaga
     2401 taaaacgccg tttttgcgtt tcctctttgc cattgagctt gagcaaatat gcccgaccca
     2461 gcctcatgac agcgatatcg actgctgtcg ttgggtcagc gccgaagaaa ttttacaggc
     2521 gtcaaatctt cgttcgccgc tggtggcgga aagtatccgt tgttatcaaa gcgggcaacg
     2581 ctatccgctg gagatgattg gcgattttaa ctggcctttt acaaagggtg tcatctaaaa
     2641 ggctgcgtga tagaatacgc cgccttgaag ttcaatgtcg tgagtgatcc aatgtctgaa
     2701 accgcaaaaa aagtaatcgt cggcatgtcc ggcggtgtcg attcctccgt ttctgcctgg
     2761 ctgttgcaac aacagggata tcaggtcgaa ggcctgttta tgaagaactg ggaagaagac
     2821 gacggtgagg aatattgcac agcggcagcg gatctggctg atgcccaggc tgtctgcgac
     2881 aagctcggca ttgaactgca caccgttaac tttgctgccg agtactggga caacgtcttc
     2941 gaactgttcc ttgccgaata taaagccggt cgcacgccga atccggatat tctgtgcaac
     3001 aaagagatca aatttaaagc cttcctcgaa tttgccgccg aagatttagg tgccgattat
     3061 atcgctaccg gtcattacgt acgtcgggcc gatgtcgatg gcaagagccg cctgctgcgt
     3121 ggtctggaca gcaataaaga ccagagctac ttcctttata cgctcagcca tgagcagatt
     3181 gcgcaaagcc tgttcccggt cggcgaactg gaaaaaccgc aggtgcgtaa gattgctgaa
     3241 gatcttggtc tggtcaccgc gaagaaaaaa gactctaccg gcatttgctt cattggcgaa
     3301 cgtaaattcc gcgagttcct gggccgttat ctcccggcgc aaccgggcaa aatcattacc
     3361 gtcgatggcg atgaaattgg tgagcaccag gggctgatgt atcacactct cggtcagcgt
     3421 aaaggtctgg gtatcggtgg caccaaagaa ggtaccgaag aaccgtggta tgtggtggac
     3481 aaagacgtcg aaaacaacat tctggttgtc gctcagggcc atgaacaccc gcggctgatg
     3541 tctgtcgggt tgattgccca gcagttgcac tgggtcgatc gcgaaccatt caccggcact
     3601 atgcgttgca cggtaaaaac ccgctatcgc cagaccgata tcccttgcac cgtcaaggcg
     3661 ctggacgatg atcgcattga agtgattttc gatgaaccgg ttgccgccgt gacgccgggc
     3721 cagtctgccg tcttctataa cggtgaagtg tgcctcggtg gcggtattat tgagcagcgt
     3781 ctgccgctgc cggtctgatt attatcttta cttaaaacaa ggaagcagtg aacgtggcaa
     3841 agaattacta tgacatcacc ctcgccctgg ccggtatttg tcagtcggca cgcctggtgc
     3901 aacaactcgc tcaccagggg cattgtgatg ccgatgcgct acacgtctca ctcaacagta
     3961 ttattgatat gaaccccagc tcgacgctgg cggtttttgg cggtagcgaa gccaacctgc
     4021 gcgtcgggct ggaaaccctg ctcggcgtgc tcaatgccag cagtcgccag ggcttaaacg
     4081 ccgaattaac ccgctacaca ctcagcttga tggtgcttga gcgcaaactc tcctcagcga
     4141 aaggcgcgct cgacactctg ggcaaccgga tcaacggcct gcaacgccag ctcgaacact
     4201 tcgatttaca gtccgaaacg ctgatgagcg cgatggctgc tatctatgtt gatgtgatca
     4261 gcccgcttgg cccgcgcatt caggtcaccg gttcccctgc tgtactgcaa agcccacaag
     4321 tgcaggcgaa agttcgcgca accctgctgg caggcattcg cgccgccgtg ctctggcacc
     4381 aggtcggcgg cggacgtctg caactgatgt tttctcgtaa tcgcctgacc actcaggcaa
     4441 aacaaattct tgctcattta accccggagt tgtgatctat ggaattatcc tcactgaccg
     4501 ccgtttcccc tgtcgatgga cgctacggcg ataaagtcag cgcgctgcgc gggattttca
     4561 gcgaatatgg tttgctgaaa ttccgtgtac aagttgaagt acgttggctg caaaaactgg
     4621 ccgcgcacgc agcgatcaag gaagttcctg cttttgctgc cgacgcaatc ggttaccttg
     4681 atgcaattgt cgccaatttc agcgaagaag atgccgcacg catcaaaacc atcgagcgta
     4741 ccactaacca cgacgttaaa gcggttgagt atttcctgaa agaaaaagtg gcggagatcc
     4801 cggaactgca cgcggtttct gaattcatcc actttgcctg tacttcggaa gatatcaata
     4861 acctctccca cgcattaatg ctgaaaaccg cgcgtgatga agtgatcctg ccgtactggc
     4921 ttcaactgat tgatggcatt aaagatctcg ccgttcagta ccgcgatatc ccgctgctgt
     4981 ctcgtaccca cggtcagcca gccacgccgt caaccatcgg taaagagatg gcaaacgtcg
     5041 cctaccgtat ggagcgccag taccgccagc ttaatcaggt ggagatcctc ggcaaaatca
     5101 acggcgcggt cggtaactat aacgcccata tcgccgctta cccggaagtt gactggcatc
     5161 agttcagcga agagttcgtc acctcgctgg gtattcagtg gaacccgtac accacccaga
     5221 tcgaaccgca cgactacatt gccgaattgt ttgattgcgt tgcgcgcttc aacaccattc
     5281 tgatcgactt tgaccgtgac gtctggggtt atatcgccct taaccacttc aaacagaaaa
     5341 ccattgctgg tgagattggt tcttccacca tgccgcataa agttaacccg attgacttcg
     5401 aaaactccga agggaatctg ggcctttcca acgcggtatt gcagcatctg gcaagcaaac
     5461 tgccggtttc ccgctggcag cgtgacctga ccgactccac cgtgctgcgt aacctcggcg
     5521 tgggtatcgg ttatgcgctg attgcgtatc aatccaccct gaaaggcgtg agcaaactgg
     5581 aagtaaaccg tgaccatctg ctggatgagc tggatcacaa ctgggaagtg ctggctgagc
     5641 caatccagac agttatgcgt cgctatggca tcgaaaaacc gtacgagaag ctgaaagagc
     5701 tgactcgcgg taagcgcgtt gacgccgaag gcatgaagca gtttatcgat ggtctggcgt
     5761 tgccagaaga agagaaagcc cgcctgaaag cgatgacgcc ggctaactat attggtcgag
     5821 ctatcaccat ggttgatgag ctgaaataaa ctcgtatcag tgccggatgg cgatgctgtc
     5881 cggcctgttt attaaaatta tccacttttt cttttttcac tttacctccc ctccccgctg
     5941 gtttatttaa tgtttacccc cataaacaca taatcgcgtt acactatttt aataattaag
     6001 acagggagaa ataaaaatgc gcgtactggt tgttgaagac aatgcgttgt tacgtcacca
     6061 ccttaaagtt cagattcagg atgctggtca tcaggtcgat gacgcagaag atgccaaaga
     6121 agccgattat tatctcaatg aacatttacc ggatattgcg attgtcgatc tcggattgcc
     6181 tgacgaggac ggtctgtcac tgattcgccg ctggcgtagc aatgatgttt cactgccgat
     6241 tctggtatta accgcccgtg aaagctggca ggacaaagtc gaagtattaa gtgccggtgc
     6301 tgatgattac gtgactaaac cgtttcatat tgaagaggtg atggcgcgaa tgcaggcatt
     6361 aatgcggcgt aatagcggcc tggcttcaca ggtcatttcg ctacccccgt ttcaggttga
     6421 tctctctcgc cgtgaattat ctattaatga cgaagtgatc aaactgaccg cgttcgaata
     6481 caccattatg gaaacgttga tacgcaataa tggcaaagtg gtgagcaaag attcgttaat
     6541 gctccaactc tatccggatg cggagctgcg ggaaagccat accattgatg tactgatggg
     6601 acgtctgcgc aaaaaaattc aggcacaata tccgcaagaa gtgattacta ccgttcgcgg
     6661 ccagggctat ttgttcgaat tgcgctgatg aaaaaattac tgcgtctttt tttcccgctc
     6721 tcactgcggg tacgttttct gttggcaacg gctgcggtag tactggtgct ttcgcttgcc
     6781 tacggaatgg tcgcgctgat cggttatagc gtcagtttcg ataaaactac gtttcggctg
     6841 ttacgtggcg agagcaatct gttctatacc cttgcgaagt gggaaaacaa taagttgcat
     6901 gtcgagttac ccgaaaatat cgacaagcaa agccccacca tgacgctaat ttatgatgag
     6961 aacgggcagc ttttatgggc gcaacgtgac gtgccctggc tgatgaagat gatccagcct
     7021 gactggctga aatcgaatgg ttttcatgaa attgaagcgg atgttaacga taccagcctc
     7081 ttgctgagtg gagatcattc gatacagcaa cagttgcagg aagtgcggga agatgatgac
     7141 gacgcggaga tgacccactc ggtggcagta aacgtctacc cggcaacatc gcggatgcca
     7201 aaattaacca ttgtggtggt ggataccatt ccggtggagc taaaaagttc ctatatggtc
     7261 tggagctggt ttatctatgt gctctcagcc aatctgctgt tagtgatccc gctgctgtgg
     7321 gtcgccgcct ggtggagttt acgccccatc gaagccctgg caaaagaagt ccgcgaactg
     7381 gaagaacata accgcgaatt gctcaatcca gccacaacgc gagaactgac cagtctggta
     7441 cgaaacctga accgattgtt aaaaagtgaa cgcgaacgtt acgacaaata ccgtacgacg
     7501 ctcaccgacc tgacccatag tctgaaaacg ccactggcgg tgctgcaaag tacgctgcgt
     7561 tctctgcgta gtgaaaagat gagcgtcagt gatgctgagc cggtaatgct ggagcaaatc
     7621 agccgcattt cacagcaaat tggctactac ctgcatcgtg ccagtatgcg cggcgggaca
     7681 ttgctcagcc gcgagctgca tccggtcgcc ccactgctgg acaatctcac ctcagcgctg
     7741 aacaaagtgt atcaacgcaa aggggtcaat atctctctcg atatttcgcc agagatcagc
     7801 tttgtcggtg agcagaacga ttttgtcgag gtgatgggca acgtgctgga taatgcctgt
     7861 aaatattgcc tcgagtttgt cgaaatttct gcaaggcaaa ccgacgagca tctctatatt
     7921 gtggtcgagg atgatggccc cggtattcca ttaagcaagc gagaggtcat tttcgaccgt
     7981 ggtcaacggg ttgatacttt acgccctggg caaggtgtag ggctggcggt agcccgcgaa
     8041 atcaccgagc aatatgaggg taaaatcgtc gccggagaga gcatgctggg cggtgcgcgg
     8101 atggaggtga tttttggtcg ccagcattct gcgccgaaag atgaataaat atgtccatac
     8161 ttcacgcatt acgttaagca tccgttataa tcggttgcag ataccagcct gtggatgctt
     8221 aacatggaat accaactcac tcttaactgg cccgattttc ttgaacgtca ctggcagaaa
     8281 cgcccggtgg tgttaaaacg cggctttaat aattttattg acccgatctc tccagacgag
     8341 ttggcgggtc tggcgatgga aagcgaagtt gacagtcgac tggtcagtca ccaggatggc
     8401 aaatggcagg tcagccacgg cccgttcgaa agctacgatc atctcggtga aaccaactgg
     8461 tcattactgg tacaggcagt gaaccactgg catgagccga ccgccgcgct gatgcgaccg
     8521 ttccgtgaac taccggactg gcgtattgat gatctgatga tctctttttc tgtaccgggc
     8581 ggcggcgtcg gcccgcatct cgatcagtac gacgtgttta tcattcaggg taccggtcgt
     8641 cgtcgctggc gagtgggcga aaagctgcaa atgaaacagc actgtccgca cccggatctg
     8701 ttacaggtcg atccgttcga agccatcatc gatgaagagc tggagcctgg cgatattctt
     8761 tatattccgc caggattccc gcatgaaggc tacgcgctgg aaaatgcgat gaactattcc
     8821 gtgggttttc gcgcgccgaa tacgcgggaa ctgattagcg gatttgccga ttatgtgctg
     8881 caacgtgaac tgggcggcaa ctactacagc gatccggatg ttccacctcg cgctcatcct
     8941 gcggatgttc tgccgcaaga gatggataaa ctgcgtgaga tgatgctcga attgatcaac
     9001 cagccggaac actttaagca atggtttggc gagtttatat cccagtcacg tcatgaactg
     9061 gatatcgcgc cgccggaacc gccttatcag ccagatgaaa tctacgatgc gctgaaacaa
     9121 ggtgatgtgc tggtgcgcct gggtggtctg cgcgtattgc gcattggcga cgacgtgtat
     9181 gccaatggtg agaagatcga ttccccgcac cgtccggcac tggatgcact cgccagcaac
     9241 attgcgctga ctgcggagaa ttttggcgat gcgctggaag atccgtcatt cctcgcaatg
     9301 ctcgcggcgc tggtaaatag cgggtattgg ttcttcgaag ggtaagtttg gatttaagcc
     9361 ggatgtggtg ctgattgcgc cttatcgtgc ctacatgcac tgaacgcctg taggcacgat
     9421 aagtatgtgg accagtgtca atataacggt ttcatcccgg taattggcag tccacatacg
     9481 catcgggcaa tcacgacttc cgttgcgccg ttaactcggc aatacggacg atcacctgca
     9541 ccgctttttc cataccttcc agagtcacaa actcatgctt accatgatag ttgtaaccgc
     9601 cagtgaacag gttcgggcaa ggtaatccca taaacgacaa ctgcgcgccg tcggtaccgc
     9661 cgcggatcgg tttcagttcc ggttcaatat cgcagtcacg catcgcctgc tgggcgatat
     9721 cgagaatatg cggatgctca accactttct cgcgcatatt gtagtaactg tcttcaatca
     9781 ccaattcaat gtagcaatca ggatgtaacc ctttgcccac ttttttggcg atctccatca
     9841 ttttacgttt acgcgcttca aactgtttac ggtcgaaatc acggatgatg taatgcatat
     9901 cggcccgttc aacggtgcct ttcatgctcg ccaggtgata gaaaccttca tagccttctg
     9961 tcatttccgg gctttcatcc gccggaactt ccgcatgaat acgtgccgcc agcgacagcg
    10021 catttaccat cactcctttc gccgtgcccg ggtgaacatt gttaccgaca attttgatat
    10081 tgaccgacgc ggcgttgaag ttttcaaact ccagttcgcc tacgccacca ccatcaacag
    10141 tgtaagccca gcgggcatcg aaggcgtcaa catcaaaatg tttcgcccct ttgcccactt
    10201 cttcatccgg ggtaaaggcg acgcgaatat caccatgcgg aatgtttttc tgttgcaata
    10261 ccgccagcgc ggtcatgatt tctgcaatac ctgctttgtc atcggcacct aacaaggttt
    10321 taccatcggt agtaatcagc gtctgaccca gtagctgatg cagcaccggg aacataaccg
    10381 gtgataaaac ttcatcgccg atacccagcg caatatcgcc accgcgatag ttttcaacaa
    10441 tttgcggatt cacatttttg ccgctgcaat ccggtgaggt atccacatga gaaataaagc
    10501 caatcgccgg gatattgcca gggacgttag ccggtaacgt cgccatcaaa gtgcccttct
    10561 cacttaaggt cacattgata agccccatct cttcgagctg ctctttcagt agatgcaata
    10621 acttccattg gccttccgtg ctgggaacct gtctcacccc tgcttttgat tgggtatcca
    10681 gagacacgta gttcaaaaat cgctcaagta gtttatccat gtagtcaccc tcactttttg
    10741 tgacaacatt attaagaagc aagaaaagac aaatattgcg tcaggtcact tttacccctg
    10801 caagcgggaa tatttatcag cattacctta atgaatataa agctaagcca gtaattcaca
    10861 acaaagattg gcgattcaag cggtttgccg tagaattacc gccctcatta agagtcacca
    10921 aggtggttaa ccacaaaccc cgcatcggta agccatccgt tgcgtttaca tgggacagag
    10981 taaaaaattg aataaacaac cgagttcgct ttcaccgctg gtgcaattgg cgggaattcg
    11041 caaatgcttt gatggtaaag aggtcattcc ccagctggat ctgactatca acaatggcga
    11101 gttcctcacg ctgcttggcc cttctggctg cggtaaaaca accgttcttc gcctgattgc
    11161 aggtctggaa actgttgatt ccggacgcat catgctggat aacgaggaca tcacccacgt
    11221 tccggcggaa aaccgctatg tgaacactgt tttccaaagc tacgcacttt tcccccacat
    11281 gaccgtgttc gaaaatgtgg cctttgggtt gcgcatgcaa aaaacccccg ctgctgaaat
    11341 tacgccccgc gttatggaag ccctgcggat ggtgcagctg gaaaccttcg ctcaacgtaa
    11401 accgcatcag ctctctggtg gtcaacagca acgcgtcgcc attgcccgtg cggtggttaa
    11461 caagcctcgt cttttgttgc tggatgagtc gctctcagcg ctggattaca aactgcgtaa
    11521 gcaaatgcag aacgagctga aagcgttaca gcgtaagctt ggcattacat tcgtcttcgt
    11581 gactcacgac caggaagaag cactcaccat gtcagacagg attgtggtga tgcgcgatgg
    11641 tcgcatcgag caagacggca cgccgcgtga aatctacgaa gagccgaaaa acctgtttgt
    11701 tgccgggttc attggcgaaa tcaatatgtt taacgcaacg gtcatcgaac gtctcgacga
    11761 gcagcgcgta cgcgccaacg ttgaaggccg cgaatgtaat atctacgtta acttcgccgt
    11821 tgaaccgggg caaaaactgc atgttctgct gcgcccggaa gacttacgtg ttgaagagat
    11881 taacgacgac aaccacgctg aagggctaat tggttacgtt cgcgagcgta actacaaagg
    11941 catgacgctg gagtcggttg ttgaactgga aaatggcaag atggtgatgg tcagcgaatt
    12001 cttcaatgaa gacgatcctg actttgacca ctctctcgac caaaaaatgg ccattaattg
    12061 ggtagaaagc tgggaggtcg tactggctga tgaagaacac aagtaagttc cagaatgtag
    12121 tgattgtcac tattgtcggt tggcttgtgt tgtttgtctt tctgcccaac ctgatgatca
    12181 ttggcaccag ctttttgacc cgcgacgacg ccagtttcgt caaaatggtc tttacgctgg
    12241 ataactatac gcgtctgctc gatccgctct attttgaagt gctattgcac tcgctgaata
    12301 tggcgctgat cgccaccctc gcctgcctgg tgctgggcta cccgtttgcc tggtttctgg
    12361 cgaagctgcc acacaaggtg cgtccgctgc tgctgtttct gctgattgtt cccttctgga
    12421 ccaactcatt gattcgtatc tacgggctga aaattttcct cagcaccaaa ggctatctca
    12481 acgagttttt gctctggctg ggcgttatag atacaccaat tcgcatcatg ttcacgccca
    12541 gtgcggtgat tatcggtctg gtttacattc tgctgccgtt tatggtgatg ccgctgtatt
    12601 ccagtatcga aaaactggat aagccgttgc ttgaggcagc gcgcgatctc ggtgccagca
    12661 agttacagac ttttatccgt atcattattc cactgacgat gccgggaatt attgccggat
    12721 gtctgctggt gatgctgcca gcgatgggcc tgttctatgt gtccgacctg atgggcggtg
    12781 cgaaaaacct gctgatcggt aacgtcatca aggtacagtt cctcaatatt cgtgactggc
    12841 cgtttggtgc agccaccagc attacgctga ctatcgtaat gggcctgatg ttgctggttt
    12901 actggcgcgc ttctcgtctg ctgaataaga aggtgagcga attagatgat taatccttta
    12961 tattcaatgc attaggtttg tttttgagtg gttttgccgt ttaaggtaac ggcattatag
    13021 atcctatcaa aatcaatcaa ttgcattctg gttttggaga aagatttttc gagaacttcg
    13081 gtctttaact aaaactgatt gcgtataatc ccaatccccc ctccccgact atctgaatgg
    13141 tcggggaggc acttcaagca caaaatatca tccctgcgcc gttgattact ctgcaggtga
    13201 agtcggccac tcaatatcag gtgcagttga tgtatcaaca cgattcaaca a
//
LOCUS       DAPGUL010000123        13231 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.125, whole genome shotgun sequence.
ACCESSION   DAPGUL010000123 DAPGUL010000000
VERSION     DAPGUL010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13231)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13231)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13231
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.125"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(139..351)
                     /gene="cspH"
                     /locus_tag="RHX21_003810"
     CDS             complement(139..351)
                     /gene="cspH"
                     /locus_tag="RHX21_003810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock-like protein CspH"
                     /protein_id="HDV1988934.1"
                     /translation="MSRKMTGIVKTFDRKSGKGFIIPSDGRKEVQVHISAFTPRDAEV
                     LIPGLRVEFCRVNGLRGPTAANVYLS"
     gene            637..849
                     /gene="cspG"
                     /locus_tag="RHX21_003811"
     CDS             637..849
                     /gene="cspG"
                     /locus_tag="RHX21_003811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock protein CspG"
                     /protein_id="HDV1988935.1"
                     /translation="MSNKMTGLVKWFNADKGFGFITPDDGSKDVFVHFTAIQSNEFRT
                     LNENQKVEFSIEQGQRGPAAANVVTL"
     gene            860..1048
                     /locus_tag="RHX21_003812"
     CDS             860..1048
                     /locus_tag="RHX21_003812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDV1988936.1"
                     /translation="MTQHLHFRCPCCHGSQYRTSAFDVTERNPLGAKCIFCKSTMITF
                     DNVALQIRTDHVPLDFTK"
     gene            1023..1253
                     /gene="ymcE"
                     /locus_tag="RHX21_003813"
     CDS             1023..1253
                     /gene="ymcE"
                     /locus_tag="RHX21_003813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YmcE"
                     /protein_id="HDV1988937.1"
                     /translation="MCRWISQNNIRLPRGAFFISALFFFNAVCIVSDNLLIIESFGEM
                     AYNISYLTRVPGTNTLLACCCLSRPEEVNSEY"
     gene            1243..1416
                     /locus_tag="RHX21_003814"
     CDS             1243..1416
                     /locus_tag="RHX21_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module toxin, GnsA/GnsB family"
                     /protein_id="HDV1988938.1"
                     /translation="MNIEELKKQAETEIADFIAQKIAELNKNTGKEVSEIRFTAREKM
                     TGLESYDVKIKIM"
     gene            complement(1464..2537)
                     /locus_tag="RHX21_003815"
     CDS             complement(1464..2537)
                     /locus_tag="RHX21_003815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDV1988939.1"
                     /translation="MAENKRTRWQRRPGTTGGKLPWNDWRNATTWRKATQLLLLATNI
                     YIAITFWYWVRYYETASSTTFVARPGGIEGWLPIAGLMNLKYSLVTGQLPSVHAAAML
                     LLVAFIVISLLLKKAFCSWLCPVGTLSELIGDLGNKLFGRQCVLPRWLDIPLRGVKYL
                     LLSFFLYIALLMPAQAIHYFMLSPYSVVMDVKMLDFFRHMGTATLISVTVLLIASLFI
                     RHAWCRYLCPYGALMGVVSLLSPFKIRRNAESCIDCGKCAKNCPSRIPVDKLIQVRTV
                     ECTGCMTCVESCPVASTLTFSLQKPAANKKAFALSGWLMTLLVLGIMFAVIGYAMYAG
                     VWQSPVPDELYRRLIPQAPMIGH"
     gene            complement(2609..5353)
                     /gene="torS"
                     /locus_tag="RHX21_003816"
     CDS             complement(2609..5353)
                     /gene="torS"
                     /locus_tag="RHX21_003816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415513.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TMAO reductase system sensor histidine
                     kinase/response regulator TorS"
                     /protein_id="HDV1988940.1"
                     /translation="MNLTLTRRLWMGFALMALLTLTSTLVGWYNLRFISQVEKDNTQA
                     LIPTMNMARQLSEASAWELFAAQNLTSADNEKMWQAQGRMLTAQSLKINALLQALREQ
                     GFDTTAIEQQEQEISRSLRQQGELVGQRLQLRQQQQQLSQQIVAAADEIARLAQGQAN
                     NAATSAGATQAGIYDLIEQDQRQAAESALDRLIDIDLEYVNQMNELRLSALRVQQMVM
                     NLGLEQIQKNAPTLEKQLNNAVKILQRRQIRIEDPGVRAQVATTLTTVSQYSDLLALF
                     QQDSEISNHLQTLAQNNIAQFAQFSSEVSQLVDTIELRNQHGLAHLEKASARGQYSLL
                     LLGMVSLCALILILWRVVYRSVTRPLAEQTQALQRLLDGDIDSPFPETAGVRELDTIG
                     RLMDAFRSNVHALNRHREQLAAQVKARTAELQELVIEHRQARAEAEKASQAKSAFLAA
                     MSHEIRTPLYGILGTAQLLADNPALNAQRDDLRAITDSGESLLTILNDILDYSAIEAG
                     GKNVSVSDEPFEPRPLLESTLQLMSGRVKGRPIRLATAIADDMPCALMGDPRRIRQVI
                     TNLLSNALRFTDEGYIILRSRTDGEQWLVEVEDSGCGIDPAKLAEIFQPFVQVSGKRG
                     GTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLPLRVATAPVPKTVNQAVRLDGL
                     RLLLIEDNPLTQRITVEMLNTSGAQVVAVGNAAQALETLQNSEPFAAALVDFDLPDVD
                     GITLARQLAQQYPSLVLIGFSAHVIDETLRQRTSSLFRGIIPKPVPREVLGQLLAHYL
                     QLQVNNDQSLDVSQLNEDAQLMGTEKIHEWLVLFTQHALPLLDEIDIARASQDSEKIK
                     RAAHQLKSSCSSLGMRIASQLCAQLEQQPLSAPLPHEEITRSVAALEAWLHKKDLNAI
                     "
     gene            5436..6464
                     /gene="torT"
                     /locus_tag="RHX21_003817"
     CDS             5436..6464
                     /gene="torT"
                     /locus_tag="RHX21_003817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TMAO reductase system periplasmic protein TorT"
                     /protein_id="HDV1988941.1"
                     /translation="MRVLLFLLLSLFMLPAFSADNLLRWHDAQHFTVQASTPLKAKRA
                     WKLCALYPSLKDSYWLSLNYGMQEAARRYGVDLKVLEAGGYSQLATQQAQIDQCKQWG
                     AEAILLGSSTTSFPDLQKQVASLPVIELVNAIDAPQVKSRVGVPWFQMGYQPGRYLVQ
                     WAHGKPLNVLLMPGPDNAGGSKEMVEGFRAAIAGSPVRIVDIALGDNDIEIQRNLLQE
                     MLERHPEIDVVAGTAIAAEAAMGEGRNLKTPLTVVSFYLSHQVYRGLKRGRVIMAASD
                     QMVWQGELAVEQAIRQLQGQSVSDNVSPPILVLTPKNADREHIRRSLSPGGFRPVYFY
                     QHTSAAKK"
     gene            complement(6437..7129)
                     /gene="torR"
                     /locus_tag="RHX21_003818"
     CDS             complement(6437..7129)
                     /gene="torR"
                     /locus_tag="RHX21_003818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator TorR"
                     /protein_id="HDV1988942.1"
                     /translation="MPHHIVIVEDEPVTQARLQSYFTQEGYTVSVTASGAGLREIMQN
                     QPVDLILLDINLPDENGLMLTRALRERSTVGIILVTGRSDRIDRIVGLEMGADDYVTK
                     PLELRELVVRVKNLLWRIDLARQAQPHTQDNCYRFAGYCLNVSRHTLERDGEPIKLTR
                     AEYEMLVAFVTNPGEILSRERLLRMLSARRVENPDLRTVDVLIRRLRHKLSADLLVTQ
                     HGEGYFLAADVC"
     gene            7259..8431
                     /gene="torC"
                     /locus_tag="RHX21_003819"
     CDS             7259..8431
                     /gene="torC"
                     /locus_tag="RHX21_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentaheme c-type cytochrome TorC"
                     /protein_id="HDV1988943.1"
                     /translation="MRKLWNALRRPSARWSVLALVAIGIVIGIALIVLPHVGIKVTST
                     TEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDIYQ
                     TFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQM
                     KVAAKDNQSCIDCHKGIAHQLPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAK
                     GDKEASGSLLPASEVKVLKRDGDWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGD
                     VQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAYADSLYNGTCNQCHG
                     APEIAHFDANGWIGTLNGMIGFTSLDKREERTLLKYLQMNASDTAGKAHGDKKEEK"
     gene            8431..10977
                     /gene="torA"
                     /locus_tag="RHX21_003820"
     CDS             8431..10977
                     /gene="torA"
                     /locus_tag="RHX21_003820"
                     /EC_number="1.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethylamine-N-oxide reductase TorA"
                     /protein_id="HDV1988944.1"
                     /translation="MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAAT
                     DAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELDKYPSKMIAGLPDHVHNAARIRY
                     PMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGW
                     QSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLV
                     LQNSKTIVLWGSDLLKNQQANWWCPDHDVYEYYAQLKAKVAAGEIEVISIDPVVTSTH
                     EYLGREHVKHIAVNPQTDVPLQLALAYTLYSENLYDKNFLANYCVGFEQFLPYLLGEK
                     DGQPKDAAWAEKLTGIDAETIRGLARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLA
                     AMLGQIGLPGGGFGFGWHYNGAGTPGRKGVILSGFSGSTSIPPVHDNSDYKGYSSTIP
                     IARFIDAILEPGKVINWNGKSVKLPPLKMCIFAGTNPFHRHQQINRIIEGWRKLETVI
                     AIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEARNDFDI
                     FRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFD
                     HPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGG
                     PGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGKEPVFINPQDASARGIRNGDV
                     VRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIG
                     TSQLAQATSAHTTLVEIEKYNGTVEQVTAFNGPVEMVAQCEYVPASQVKS"
     gene            10974..11573
                     /gene="torD"
                     /locus_tag="RHX21_003821"
     CDS             10974..11573
                     /gene="torD"
                     /locus_tag="RHX21_003821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone TorD"
                     /protein_id="HDV1988945.1"
                     /translation="MTTLTAQQIACIYAWLAQLFSRELDDEQLTQIASAQMAEWFSLL
                     KSEPPLAAAVNALENRIAALTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQ
                     EIKRLLVEAGMETSGNFNEPADHLAIYLELLSHLHFSLGEGTVPARRIDSLRQKTLTA
                     LWQWLPEFVARCHQHDSFGFYAALSQLLLVLVECDHQNR"
     gene            complement(11666..11971)
                     /gene="cbpM"
                     /locus_tag="RHX21_003822"
     CDS             complement(11666..11971)
                     /gene="cbpM"
                     /locus_tag="RHX21_003822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone modulator CbpM"
                     /protein_id="HDV1988946.1"
                     /translation="MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPREIQETTWV
                     FDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVTHP"
     gene            complement(11971..12891)
                     /gene="cbpA"
                     /locus_tag="RHX21_003823"
     CDS             complement(11971..12891)
                     /gene="cbpA"
                     /locus_tag="RHX21_003823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curved DNA-binding protein"
                     /protein_id="HDV1988947.1"
                     /translation="MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEA
                     RFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFNRQFHHSDGQSFNAEDFDDIFSSIF
                     GQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTL
                     NVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGHDLEIVVPVS
                     PWEAALGAKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMP
                     PKPDENTAALWQQLADAQSSFDPRKDWGKA"
BASE COUNT         3228 a         3344 c         3462 g         3197 t
ORIGIN      
        1 tttataacta ttaggtgcag agatattcgc ttaaatggat tagtttcttt gtggaaaagt
       61 aactgatgtt ataatgtatg atgttgacta ttgcactatt ccaataaaac cagtcagctt
      121 taaacaagca gcgtcatatt aagagagata aacatttgcc gctgttggtc ctcgcaggcc
      181 atttacgcgg caaaattcca cacgtaatcc tggtataagc acttctgcgt cgcggggagt
      241 gaatgcggaa atatggacct gaacttcttt acgaccgtcg gaggggataa tgaatccttt
      301 gccgcttttg cgatcaaagg ttttgacaat tcctgtcatt ttacgggaca aacaaattcc
      361 ttactgaaaa tactgcgctg cactatacgg ggttaataaa ataaagccag cgatatttaa
      421 gaccgccgga cggctaaaat aaaatttgct taatctcaat tatcatgcgt taatagctgc
      481 gtcggtttga aagacagaca gcatacaaag tagtttacta aagcagttct cattatcagg
      541 cattatcccc ttcttttgag tctctctcct gaacactaag tagtttctgt attaaagccc
      601 tgtttgccga aaggcccaaa atgaaggaag taaaatatgt ctaataaaat gactggttta
      661 gtaaaatggt ttaacgcaga taaaggtttt ggctttatca ctcctgatga tggcagcaaa
      721 gacgttttcg tccatttcac cgccatccag agcaatgaat tccgcacgct gaacgaaaat
      781 cagaaagttg aattttctat tgagcagggg caacgtggcc ccgcggcagc gaacgttgtt
      841 acgctctaag gttgccgtta ttactcaaca tctccatttc cgctgtccat gttgtcatgg
      901 ttcacagtac cgcacatcgg cattcgatgt gacggagcga aaccctttgg gcgctaagtg
      961 tattttttgt aaatcgacga tgatcacctt tgataacgtc gcgctgcaaa tacgcactga
     1021 ccatgtgccg ctggatttca caaaataata tcaggctccc tcgtggagcc ttttttatat
     1081 ctgccttatt tttcttcaac gctgtatgta tagtaagcga taacctgttg attattgaat
     1141 ctttcgggga gatggcttat aacatttctt acctgaccag ggtaccggga accaacacct
     1201 tactggcgtg ttgctgtctt tcaagaccag aagaggttaa cagtgaatat tgaagagtta
     1261 aaaaaacaag ccgaaacgga aatcgccgac tttatcgcgc aaaaaatcgc cgagctgaac
     1321 aagaatacag ggaaagaagt ctctgaaatt cgcttcaccg cacgagaaaa aatgaccggg
     1381 cttgaaagtt atgatgtcaa aatcaaaata atgtgatttt gtgaacatca cccgtgcgag
     1441 gtgatgttcc gcttgttgct aatttagtga ccaatcattg gcgcttgtgg aattaagcgt
     1501 cggtacaatt catccggtac cgggctttgc catactcccg catacattgc gtaaccaatc
     1561 accgcaaaca taatccccag aaccagtagc gtcattaacc agccagacaa cgcaaaggct
     1621 tttttatttg ccgcaggttt ttgcagtgaa aaggtcaatg ttgaggctac cggacatgac
     1681 tctacgcaag tcatacagcc ggtacattcc actgttcgta cctgaattaa tttatcgacc
     1741 gggatccgtg atgggcaatt ttttgcgcat ttgccacagt cgatacaact ttcggcattg
     1801 cgacgaatct taaacggcga caatagcgaa accacgccca tcagcgcgcc atatgggcaa
     1861 agataacgac accaggcatg gcgaataaac aggctggcaa tcagcaaaac ggtcacgctg
     1921 attaatgtcg cggtccccat atgacgaaag aaatcgagca ttttaacgtc catcaccacg
     1981 ctgtagggcg acaacataaa atagtgaatc gcctgagcgg gcatcaataa cgcgatatag
     2041 agaaaaaaac tcaacagcaa atacttcacg ccgcgcagag gaatatccag ccagcgggga
     2101 aggacacatt gccgaccaaa cagtttgtta ccgagatcgc cgattaattc agaaagcgta
     2161 ccaaccgggc ataaccatga gcaaaaggcc tttttgagta atagactgat gacgataaaa
     2221 gcgaccaata acagcatcgc ggcggcgtgg acggacggta actgacctgt tacaaggcta
     2281 tatttcagat tcatcagccc ggcaatcggt agccagcctt cgatacctcc cggtctggcg
     2341 acaaatgtcg tgctacttgc cgtttcgtaa tagcgcaccc aataccagaa cgtgatggca
     2401 atataaatat tcgttgccaa cagtaataat tgcgtcgctt tacgccaggt cgtggcatta
     2461 cgccagtcat tccacggtaa tttgccgccc gtcgtgcctg gccgccgctg ccagcgggtt
     2521 cttttattct ctgccatgat tttgccagtc cgttaagttg tataccaaat gccactattc
     2581 tagttgttct taactggctg atattgattc aaatcgcgtt caggtctttc ttatgcaacc
     2641 atgcttccag agcggcaaca ctgcgtgtaa tttcttcgtg tggaaggggg gcagataatg
     2701 gctgctgctc cagttgtgcg catagctggc tggcgatacg cattcccaga ctcgagcaac
     2761 tgctttttag ctgatgcgcg gcacgcttta ttttctcgct atcctgactg gcgcgggcaa
     2821 tgtcgatttc atcgagaagc ggcagggcat gttgtgtaaa taataccagc cattcgtgga
     2881 tcttctccgt ccccattaac tgagcatctt cattgagttg cgatacatcc agcgattgat
     2941 cgttattgac ttgcagttgg agatagtgcg ccagtaactg accgagcact tcacgcggca
     3001 ccggtttagg gataatcccg cggaataatg aactggtacg ctggcgcagc gtttcgtcaa
     3061 tgacatgggc gctaaagcca atcaaaacca gcgacggata ttgctgtgcc agttgtcggg
     3121 caagcgtaat gccgtcgaca tccggcagat caaaatccac cagtgcggca gcaaacggtt
     3181 cgctattttg cagtgtctct aaagcctgcg cggcattgcc aacagcaaca acctgcgcac
     3241 cactggtgtt cagcatctca acggtaattc gctgggttag cgggttatct tcaattaaca
     3301 gcaaacgtaa accgtcaaga cgcaccgcct gattgactgt ttttggcacg ggtgccgtgg
     3361 caacacgtaa cggcaagcgt aaacaaaaac agcttccaac ctccggcgtg ctggtggcgc
     3421 tcagttcgcc gcccatcgcc tgggccagac ggctactgat agtcagcccc agcccggtgc
     3481 cgccgcgttt gccgcttacc tgcacaaatg gctggaagat ttctgccagt ttcgcgggat
     3541 caataccgca gccgctgtct tccacttcga ccagccattg ctcgccatca gtgcgactac
     3601 gcaggataat gtacccttcg tcagtaaaac gcagggcgtt gctcaacagg ttggttataa
     3661 cctgacgaat acgtcgtgga tcgcccatta acgcgcacgg catatcatcg gcaattgccg
     3721 ttgccaggcg aatcgggcga cctttcaccc gtccgctcat taattgcagg gtactttcca
     3781 gcagcgggcg cggttcaaag ggctcatcgc tgaccgaaac attcttgcca cctgcttcga
     3841 tagcggaata atcgagaata tcgttgagga tggtcagcaa cgattcacca gagtcagtaa
     3901 ttgcccgcaa atcatcacgc tgggcgttaa gtgcggggtt atctgccagc agttgagcag
     3961 tgccgagaat accgtacagc ggtgtgcgga tctcatggct catcgccgcc agaaacgccg
     4021 attttgcctg gctggctttt tctgcttccg cccgtgcctg tcggtgttct atcaccagtt
     4081 cctgcaattc agctgtacgc gctttgacct gcgccgccag ctgttcgcgg tggcgattca
     4141 gtgcatgaac attgctgcga aacgcatcca tcagccgccc gatggtatcc agctcccgta
     4201 cgccagcggt ttccgggaaa ggggagtcaa tatcaccgtc cagcagccgt tgcagcgcct
     4261 gcgtttgttc ggcaagtgga cgcgtgactg agcgataaac cacgcgccaa aggatcagaa
     4321 tcagtgcgca aagtgaaacc atccccagca ataacaggct gtattgcccg cgtgcactgg
     4381 ctttttccag atgtgccagt ccatgctgat tgcgcagctc aatggtgtcg accagctgac
     4441 tgacttcgct actaaactgc gcgaactggg cgatattatt ttgggcgaga gtttgcaggt
     4501 gattgctgat ttcactgtcc tgctggaaca gcgccaacag atcgctatat tggctaacgg
     4561 tagttaacgt tgttgcgacc tgcgcacgaa cacccggatc ttcaatgcgt atttgccgac
     4621 gttgcagaat tttcaccgca ttattgagct gcttttccag cgttggcgca tttttctgga
     4681 tctgctccag ccccagattc atcaccattt gctgcacccg cagggcgcta aggcgcagtt
     4741 cattcatctg gttaacatac tcaagatcga tatcaatcag ccgatcgagt gcactttctg
     4801 cggcctgacg ctgatcttgt tcgatcaaat cgtaaatccc ggcctgggtc gctccggcgg
     4861 aggttgccgc attattcgcc tgaccttgcg ccaggcgtgc gatctcatcg gcggcagcga
     4921 ctatctgctg actgagttgc tgttgttgct ggcgcagttg caaacgctgc cccaccagtt
     4981 ccccttgctg acgtaacgaa cgggagatct cctgctcctg ttgttcaata gcggtggtat
     5041 caaaaccttg ttcccgtaac gcttgcagca acgcattaat cttcaggctt tgtgcggtga
     5101 gcattcgccc ctgcgcctgc cacatctttt cgttatcggc actggtcagg ttctgcgcgg
     5161 cgaaaagttc ccaggcgctg gcttcgctca actggcgcgc catattcatg gtaggaatca
     5221 atgcctgagt attgtctttt tccacctggc tgataaagcg caggttgtac catcccacca
     5281 gggtactggt cagggttaac agcgccatca gggcaaagcc catccagagt cttcgggtca
     5341 gggttaaatt cacggtcggt gcactttagg tgaaaaaggt tgagtcgcaa agcggaatgc
     5401 atctagcata aagccttatt attgatgagg ctatcatgcg cgtactgcta tttttacttc
     5461 tttccctttt catgttgccg gcattttcgg ctgataacct gttgcgctgg catgatgcgc
     5521 agcatttcac ggtgcaagcc tctacgccgc ttaaagccaa acgcgcatgg aaactgtgcg
     5581 cgctttatcc cagcctgaaa gattcatatt ggttatcgtt gaactatggt atgcaggagg
     5641 ctgctcgccg ctacggtgtg gatttaaaag tgctggaggc aggcggctac agccagttgg
     5701 ctacccagca agcacaaatc gaccagtgta aacagtgggg cgcagaggcc attttgctcg
     5761 gtagtagcac gacctcattt cccgacctgc aaaagcaggt agcaagtctg ccggtgatcg
     5821 aactggtaaa tgctattgat gctccccagg tgaaaagccg cgttggtgtg ccctggtttc
     5881 agatgggcta tcaaccgggg cgatatctgg tgcaatgggc gcacggtaaa ccactgaatg
     5941 tgctgttgat gcccggaccc gataacgccg ggggcagtaa ggagatggtc gagggttttc
     6001 gcgcagccat tgccggaagc ccggtgcgta ttgttgatat tgcgcttggt gataacgata
     6061 ttgaaatcca gcgtaacctg ttgcaggaga tgctggaacg ccacccagaa atcgacgtcg
     6121 ttgccggaac ggccattgcg gcagaggcgg caatgggtga agggcgtaac ctgaaaacgc
     6181 cgcttaccgt ggtgtcgttt tatctttcac atcaggtgta tcgcgggctg aagcggggaa
     6241 gagtgattat ggctgccagc gatcaaatgg tctggcaggg ggaactggca gttgagcagg
     6301 ccatcaggca attacagggg caatcggtgt ctgataatgt cagcccaccg attttagttc
     6361 tgacgccgaa aaatgccgac cgagaacata tccgccgctc gctgtcacca gggggatttc
     6421 gtccggtcta tttttatcag cacacatcag cggctaagaa ataaccttca ccatgttgcg
     6481 tcaccagtaa atccgcgctg agtttatgac gtaaacgacg aattaacaca tcgacggtgc
     6541 gcaggtcagg gttttccacc cgacgcgcag aaagcatacg tagcagacgt tcacggctga
     6601 gaatttcgcc cggattcgtc acaaatgcca ccaacatttc atactctgcg cgggtcagtt
     6661 taatcggctc gccatcccgc tccagcgtat ggcgcgacac attcaggcaa taaccggcaa
     6721 agcgatagca gttgtcctga gtgtgcggtt gagcttgtcg cgcgaggtcg attcgccaga
     6781 gcagattttt cacccgtact accagttcgc gcagttccag cggtttggtg acgtaatcgt
     6841 ctgcgcccat ttccagccca acaatacggt caatccgatc gctgcgtccg gtaaccagaa
     6901 taatccccac cgttgagcgt tctcgcaggg cgcgggttaa catcaggcca ttttcatcgg
     6961 gtaagttgat atccagcaga attaaatcta ccggctgatt ctgcataatt tcccgcagcc
     7021 cggcaccgct cgctgtaacg gaaacggtat acccctcctg agtgaagtaa gattgtaatc
     7081 gcgcctgggt aaccggctca tcttcaacaa taacaatgtg atgtggcatc agagggtttt
     7141 actcattctg ttcatatctg ttcatattct gccgtaagcc gttcatcctg accagtgccg
     7201 ctgttcatat ttgctcatta agatcgcttc actaaaccat aattttacag gggctattat
     7261 gcggaaactc tggaacgcgc tacgccgacc cagtgctcgt tggtcggtac tggcgctggt
     7321 cgcaattggg attgtgattg gcattgcgct gattgtattg ccacacgttg ggatcaaagt
     7381 caccagcaca accgaatttt gtgtcagttg ccacagtatg caaccggtgt atgaagaata
     7441 taaacagtcg gtgcatttcc agaacgcctc cggcgtgcga gctgaatgcc atgactgtca
     7501 tatcccgccg gatattccag gcatggtgaa gcgcaaactg gaagcgagca atgatatcta
     7561 ccagaccttt attgctcact ccattgatac acctgaaaaa ttcgaagcca aacgcgcgga
     7621 acttgccgag cgtgaatggg cgcgaatgaa agaaaacaac tcggcaacct gccgctcctg
     7681 ccataactac gatgcgatgg atcatgcgaa gcagcatcct gaagcggcac gtcagatgaa
     7741 ggtggcagcg aaagataatc aatcctgcat cgactgtcat aaaggtattg cccaccagtt
     7801 accggatatg agtagcggct tccgtaagca gttcgatgag ctgcgcgcca gtgctaatga
     7861 cagtggtgac acgctgtact ctattgatat taagccaatt tatgcggcga aaggcgataa
     7921 agaagcctct ggttctctgc tgcctgcttc ggaagtgaaa gtccttaaac gtgacggcga
     7981 ctggctgcaa attgaaatta ccggctggac ggaaagcgcc ggacgtcagc gtgtactcac
     8041 ccaattccca ggtaaacgca tctttgttgc ctcgattcgt ggtgatgtgc agcagcaggt
     8101 aaaaacgctg gagaaaacca ccgttgccga caccaatacc gagtggagca agttgcaggc
     8161 cactgcgtgg atgaagaaag gcgacatggt gaacgatatc aaaccgatct gggcttatgc
     8221 ggattcgttg tacaacggca cctgtaacca gtgccacggc gcaccggaaa tcgcccactt
     8281 tgacgctaac ggttggatcg gcacgctcaa cggcatgatt ggctttacca gtctcgataa
     8341 acgtgaagaa cgcaccttgt tgaaatatct gcaaatgaat gcgtctgaca ccgcaggtaa
     8401 ggctcacggc gataagaagg aagaaaaata atgaacaata acgatctctt tcaggcatca
     8461 cgtcggcgtt ttctggcaca actcggcggc ttaaccgtcg ccgggatgct ggggccgtca
     8521 ttgttaacgc cgcgccgtgc gactgcggcg caagcggcga ctgacgctgt catctcgaaa
     8581 gagggcattc ttaccgggtc gcactggggg gctatccgcg cgacggtgaa ggatggtcgc
     8641 tttgtggcgg caaaaccgtt cgaactggat aaatatccgt cgaaaatgat tgccggattg
     8701 ccggatcacg tacacaacgc ggcgcgtatt cgttatccga tggtacgcgt ggactggctg
     8761 cgtaagcgcc atctcagcga tacctcccag cgcggtgata accgttttgt gcgcgtgagc
     8821 tgggatgaag ccctcgacat gttctatgaa gaactggaac gcgtgcagaa aactcacggg
     8881 ccgagtgcct tgctgaccgc cagtggttgg caatcgacgg ggatgttcca taacgcttcg
     8941 gggatgctgg cgaaagctat tgccttgcat ggtaatagcg ttggtacggg cggagattac
     9001 tctaccggtg ctgcgcaggt gatcctgccg cgcgtggttg gctcaatgga agtgtatgaa
     9061 cagcaaacct cctggccgct ggtattgcag aacagcaaaa ccattgtgct gtggggctct
     9121 gatttgctga aaaaccagca agcgaactgg tggtgcccgg atcacgatgt ttatgaatat
     9181 tacgcgcagc taaaagcgaa agtcgccgcc ggtgaaattg aggtcatcag catcgatccg
     9241 gttgtcacat ccacccatga gtatctgggg cgcgagcatg tgaagcacat tgcggttaac
     9301 ccgcaaactg atgtgccgct gcaactggcg ctggcgtata cgctgtacag tgaaaacctg
     9361 tacgacaaaa acttcctcgc taactactgt gtgggttttg agcagttcct gccgtacctg
     9421 ctgggtgaga aagacggtca gccgaaagat gccgcatggg ctgaaaaact gaccggcatt
     9481 gatgccgaaa ccattcgtgg gctggcgcgg cagatggcgg cgaacagaac gcaaattatt
     9541 gctggctggt gcgtgcagcg tatgcagcac ggtgaacagt gggcgtggat gattgtggtt
     9601 ctggcggcga tgctggggca aattggcctg ccaggtggtg gctttggttt tggctggcac
     9661 tataacggcg caggcacgcc ggggcgtaaa ggcgttattc tgagtggttt ctccggctct
     9721 acgtcgattc cgcctgttca cgacaacagt gattacaaag gctacagcag caccattccg
     9781 attgcccgtt ttatcgatgc gatcctcgaa ccggggaaag tgatcaactg gaacggtaaa
     9841 tcggtaaaac tgccgccgct gaaaatgtgt atttttgccg gaactaaccc attccatcgc
     9901 catcagcaga tcaaccgcat tattgaaggc tggcgcaagc tggaaacggt tatcgccata
     9961 gataaccagt ggacctcaac ctgccgcttt gccgatatcg tgctgcctgc gaccacgcag
    10021 tttgagcgta acgatctcga ccagtacggc aaccactcca accgtggcat tatcgccatg
    10081 aaacaggtgg tgccgccgca gttcgaggcg cgcaacgact ttgatatttt ccgcgagctg
    10141 tgccgtcgct ttaatcgcga agaagccttt accgaagggc tggacgaaat gggctggctg
    10201 aaacgcatct ggcaggaagg tgtacagcaa ggcaaaggac gcggcgttca tctgccagcg
    10261 tttgatgact tctggaataa caaagagtac gtcgagtttg accatccgca gatgtttgtt
    10321 cgccaccagg cattccgcga agatccggat ctcgaaccgc tgggcacgcc gagtggcctg
    10381 attgagatct actcgaaaac catcgccgat atgaactacg acgattgtca ggggcatccg
    10441 atgtggtttg agaaaatcga acgctcccac ggtgggcccg gctcgcagaa gtatccgttg
    10501 catctgcaat ctgtgcatcc ggattttcga cttcactcgc agttatgtga gtcggaaact
    10561 ctgcgtcagc aatatacggt agcgggtaaa gagccagtat tcattaaccc gcaggatgcc
    10621 agcgcgcgcg gtattcgtaa cggtgatgtg gtacgcgtct ttaacgctcg cggtcaggtg
    10681 ttggcagggg cagtggtttc tgaccgctat gcacccggtg tggcacgaat tcacgaaggg
    10741 gcatggtacg atccagataa aggcggcgag cctggtgcgc tgtgcaaata cggtaacccc
    10801 aacgtgttga ccatcgacat cggtacatcg cagctggcgc aggcgaccag tgcgcacact
    10861 acgctggtgg aaattgagaa gtacaacgga acagtggagc aggtgacggc gtttaacggc
    10921 cccgtggaga tggtggcgca gtgcgaatat gttcccgcgt cgcaggtgaa atcatgacca
    10981 cgctgacagc acaacagatt gcctgtattt acgcctggct ggcgcagttg ttctcccgtg
    11041 aactggacga tgaacaactg acgcaaatcg ccagtgcgca gatggctgaa tggttttcgt
    11101 tgctgaaaag cgaaccgccg ctggctgcgg cggtgaatgc gctggaaaac cgtattgccg
    11161 ctctgacagt acgtgacgat gcccgtctgg aactggccgc tgacttttgc ggcctgtttc
    11221 tgatgaccga caaacaagcg gcgctgccgt atgcatcggc ctacaaacag gacgagcaag
    11281 agattaaacg cttgttagtt gaggcaggga tggaaaccag cggcaatttc aacgaaccgg
    11341 cagatcatct ggcgatctat ctcgagttgt tgagtcatct gcatttttcg ctgggagagg
    11401 ggaccgttcc tgcgcgaaga atcgacagtt tgcggcaaaa aacactgacg gcgctgtggc
    11461 aatggttacc agagtttgtt gcgcgttgcc atcagcatga cagctttggt ttttacgcgg
    11521 cactaagcca gttattgctg gtgttagtgg agtgcgacca ccaaaacaga taacgtcgtt
    11581 tgtgcgcctg aaaagacgcg tttagcgtcg catcaggcat tatggggcag ttgccggatg
    11641 cgtcatcaca tccggcaaac acacatcacg gatgagttac aaaccgggaa agtcgctggc
    11701 gcagcaggcg gttttcctgc ttcaggtgcg caatatcatc cattaacgtc agcgccaccg
    11761 cgatcccagg ccagtccaga gccagttcat gacgcaggcg tactgcgcgt tgcaccacga
    11821 tggcggcatg gtcgtcaaat acccaggttg tttcctggat ctcacgcggt tcaaccaccc
    11881 ccaaaccgac aatttcattc aactcctctt cagagatgcc ggtatgcagg caaaattcgg
    11941 taatagtaaa agtcaccgta acattagcca ttatgctttc ccccaatctt tacgtggatc
    12001 aaaagacgac tgggcgtctg ccagttgctg ccacagcgcg gcagtgtttt catccggttt
    12061 cggcggcatc acgattttca gtaccgcata cagatcgccg gtctgttttt tgctcaccag
    12121 acctttgcct ttaacgcgca atcgttgccc ggcctggctg cctggcggga tagtcagcaa
    12181 aatgctttct ttcagtgttg gaacggtgac tttagcaccc agcgccgctt cccacgggct
    12241 aaccggcact acaatttcca gatcatggcc gacaatatcg aacagcggat gtggcgcaat
    12301 atgaatcacc agccacaaat cgccatttgg accgccgttt tcgcccggcg tcccctggcc
    12361 tttcagacgg atgcgttgac cattgccgac gcccgccggg atcttgacat tcagcgtttt
    12421 cggaatttcc tgttcgatca tgccaaaggc gttataaacc ggcaggttat agctgatggt
    12481 acgcttatgc tcagtcagcg tttcttcgag gaataccgcc acttcgattt caatatcgtg
    12541 gccgcgtgtg gcggggcgtt gacggctctg gcgggcatgc tgaccgaaaa ttgacgagaa
    12601 gatatcgtca aaatcttcgg cgttaaaact ctgaccgtcg ctatgatgga actgacggtt
    12661 aaattgcgga tcgttgcgat gttgccacat ctgatcatac tcagcgcgac gttgttcatc
    12721 acttaacact tcccaggctt cagcgacctc tttgaagcgg gcttcggcat ccggttcttt
    12781 gctgacatca ggatggtatt tgcgggccag tcgacgatag gcggtcttga ttgtcttgag
    12841 atcgtccgtc ggtttcacgc ccatgatggc gtaataatcc tttaattcca tagcgttatc
    12901 tcgcgtaaat caacacaaat tgaaggaacc cctgtaaggt aactcctata agtgtagggt
    12961 aatcctcaaa atttcatatg ccaacacaga atatgttatt gaaatcatcg cggagaggag
    13021 gtcgcctcaa ggtggggtgc tgaacatatt ttaaacaggt gaaaaagggt gagcgatttt
    13081 tgatagttga accaggcact ttaagtttaa ctggggcgtc attatttatt aaattttata
    13141 gacgctatat atgggtagta atatacatgg aattagttgc actgcaaata attatttgaa
    13201 acaggcctgg aacgatataa aaaatgagta c
//
LOCUS       DAPGUL010000124        13228 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.126, whole genome shotgun sequence.
ACCESSION   DAPGUL010000124 DAPGUL010000000
VERSION     DAPGUL010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13228
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.126"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..690
                     /locus_tag="RHX21_003824"
     CDS             <1..690
                     /locus_tag="RHX21_003824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDV1988948.1"
                     /translation="CILDDSNFPQIKMADGTLNACSAMHVQFYNAAMNRANIKNTFLD
                     YSNFYMAYMAEVNLYKVIAPYVNLFKADLSFSKLDLINFEHADLSRVNLNKAILQNIN
                     LIDSKLFCTWLTNTFLEMVICTDSNMANVNFNNANLSNCHFNCSILTKACMFNTRLYR
                     VNFDEASVQGMGISILRGEENIPIDSDTLVTRQKFFEEDCTSHTGMSQTEDNINAVAM
                     KITADIMQHAD"
     gene            complement(844..2493)
                     /locus_tag="RHX21_003825"
     CDS             complement(844..2493)
                     /locus_tag="RHX21_003825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter"
                     /protein_id="HDV1988949.1"
                     /translation="MEIFFTILIMTLVVSLSGVVTRVMPFQIPLPLMQIAIGALLAWP
                     TFGLHVEFDPELFLVLFIPPLLFADGWKTPTREFLEHGREIFGLALALVVVTVVGIGF
                     LIYWVVPGIPLIPAFALAAVLSPTDAVALSGIVGEGRIPKKIMGILQGEALMNDASGL
                     VSLKFAVAVAMGTMIFTVGGATVEFMKVAIGGILAGFVVSWLYGRSLRFLSRWGGDEP
                     ATQIVLLFLLPFASYLIAEHIGVSGILAAVAAGMTITRSGVMRRAPLAMRLRANSTWA
                     MLEFVFNGMVFLLLGLQLPGILETSLMAAEIDPNVEIWMLFTDIILIYAALMLVRFGW
                     LWTMKKFSNRFLKKKPMEFGSWTTREILIASFAGVRGAITLAGVLSIPLLLPDGNVFP
                     ARYELVFLAAGVILFSLFVGVVMLPILLQHIEVADHSQQLKEERIARAATAEVAIVAI
                     QKMEERLAADTEENIDNQLLTEVSSRVIGNLRRRADGRNDVESSVQEENLERRFRLAA
                     LRSERAELYHLRATREISNETLQKLLHDLDLLEALLIEENQ"
     gene            complement(2644..3993)
                     /gene="ghxP"
                     /locus_tag="RHX21_003826"
                     /gene_synonym="yjcD"
     CDS             complement(2644..3993)
                     /gene="ghxP"
                     /locus_tag="RHX21_003826"
                     /gene_synonym="yjcD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine/hypoxanthine transporter GhxP"
                     /protein_id="HDV1988950.1"
                     /translation="MSTPSARTGGSLDAWFKISQRGSTVRQEVVAGLTTFLAMVYSVI
                     VVPGMLGKAGFPPAAVFVATCLVAGLGSIVMGLWANLPLAIGCAISLTAFTAFSLVLG
                     QHISVPVALGAVFLMGVLFTVISATGIRSWILRNLPHGVAHGTGIGIGLFLLLIAANG
                     VGLVIKNPLDGLPVALGDFATFPVIMSLVGLAVIIGLEKLKVPGGILLTIIGISIVGL
                     IFDPNVHFSGVFAMPSLSDENGNSLIGSLDIMGALNPVVLPSVLALVMTAVFDATGTI
                     RAVAGQANLLDKDGQIIDGGKALTTDSMSSVFSGLVGAAPAAVYIESAAGTAAGGKTG
                     LTAITVGVLFLLILFLSPLSYLVPGYATAPALMYVGLLMLSNVAKIDFADFVDAMAGL
                     VTAVFIVLTCNIVTGIMIGFATLVIGRLVSGEWRKLNIGTVVIAVALVTFYAGGWAI"
     gene            complement(4539..5003)
                     /gene="soxR"
                     /locus_tag="RHX21_003827"
     CDS             complement(4539..5003)
                     /gene="soxR"
                     /locus_tag="RHX21_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensitive transcriptional activator SoxR"
                     /protein_id="HDV1988951.1"
                     /translation="MEKKLPRIKALLTPGEVAKRSGVAVSALHFYESKGLITSIRNSG
                     NQRRYKRDVLRYVAIIKIAQRIGIPLATIGEAFGVLPEGHTLSAKEWKQLSSQWREEL
                     DRRIHTLVALRDELDGCIGCGCLSRSDCPLRNPGDRLGEEGTGARLLEDEQN"
     gene            5089..5412
                     /gene="soxS"
                     /locus_tag="RHX21_003828"
     CDS             5089..5412
                     /gene="soxS"
                     /locus_tag="RHX21_003828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide response transcriptional regulator
                     SoxS"
                     /protein_id="HDV1988952.1"
                     /translation="MSHQKIIQDLIAWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRT
                     VTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDLGYVSQQTFSRVFRRQFDRTPSD
                     YRHRL"
     gene            complement(5415..7001)
                     /gene="pdeC"
                     /locus_tag="RHX21_003829"
     CDS             complement(5415..7001)
                     /gene="pdeC"
                     /locus_tag="RHX21_003829"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="c-di-GMP phosphodiesterase PdeC"
                     /protein_id="HDV1988953.1"
                     /translation="MSHRARHQLLALPGIIFLVLFPIILSLWIAFLWAKSEVNNQLRT
                     FAQLALDKSELVIRQADLVSDAAERYQGQVCTPAHQKRMLNIIRGYLYINELIYARDN
                     HFLCSSLIAPVNGYTIAPADYKREPNVSIYYYRDTPFFSGYKMTYMQRGNYVAVINPL
                     FWSEVMSDDPTLQWGVYDTVTKTFFSLSKEASAATFSPLIHLKDLTVQRNGYLYATVY
                     STKRPIAAIVATSYQRLITHFYNHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQ
                     RALEKHQLCLYYQPIIDIKTEKCIGAEALLRWLGEQGQIMNPAEFIPLAEKEGMIEQI
                     TDYVIDNVFRDLGDYLATHADRYVSINLSASDFHTSRLIARINQKTEQYAVRPQQIKF
                     EVTEHAFLDVEKMTPIILAFRQAGYEVAIDDFGIGYSNLHNLKSLNVDILKIDKSFVE
                     TLTTHKTSHLIAEHIIELAHSLGLKTIAEGVETEEQVNWLRKRGVRYCQGWFFAKAMP
                     PQVFMQWMEQLPARELTRGQ"
     gene            7431..7712
                     /locus_tag="RHX21_003830"
     CDS             7431..7712
                     /locus_tag="RHX21_003830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjcB family protein"
                     /protein_id="HDV1988954.1"
                     /translation="MATLTTGVVLLRWQLLSAVMMFLASTLNIRFRRSDYVGLAVISS
                     GLGVVSACWFAMGLLGITMADITAIWHNIESVMIEEMNQTPPQWPMILT"
     gene            complement(7811..8347)
                     /gene="ssb1"
                     /locus_tag="RHX21_003831"
     CDS             complement(7811..8347)
                     /gene="ssb1"
                     /locus_tag="RHX21_003831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SSB1"
                     /protein_id="HDV1988955.1"
                     /translation="MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDK
                     ATGEMKEQTEWHRVVLFGKLAEVASEYLRKGSQVYIEGQLRTRKWTDQSGQDRYTTEV
                     VVNVGGTMQMLGGRQGGGAPAGGNIGGGQPQGGWGQPQQPQGGNQFSGGAQSRPQQSA
                     PAAPSNEPPMDFDDDIPF"
     gene            8601..11423
                     /gene="uvrA"
                     /locus_tag="RHX21_003832"
     CDS             8601..11423
                     /gene="uvrA"
                     /locus_tag="RHX21_003832"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDV1988956.1"
                     /translation="MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDT
                     LYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTIT
                     EIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKG
                     EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLA
                     ESFETALELSGGTAVVADMDDPKAEELLFSANFACPICGYSMRELEPRLFSFNNPAGA
                     CPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQMLKSLADHYKFDVEA
                     PWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSA
                     VREELAKFISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAG
                     QRAKIAEKILKEIGDRLKFLVNVGLNYLTLSRSAETLSGGEAQRIRLASQIGAGLVGV
                     MYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDIGPGAGV
                     HGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLK
                     DVTLTLPVGLFTCITGVSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHF
                     DKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPESRARGYTPGRFSFNVRGGRC
                     EACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEARE
                     FFDAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYIL
                     DEPTTGLHFADIQQLLDVLHKLRDQGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGE
                     ILVSGTPETVAECEASHTARFLKPML"
     gene            complement(11458..11814)
                     /locus_tag="RHX21_003833"
     CDS             complement(11458..11814)
                     /locus_tag="RHX21_003833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HDV1988957.1"
                     /translation="MTISELLQYCMAKPGAEQSVHNDWKATQIKVEDVLFAMVKEVEN
                     RPAVSLKTSPELAELLRQQHSDVRPSRHLNKAHWSTVYLDGSLPDSQIYYLVDASYQQ
                     AVNLLPEEKRKLLVQL"
     gene            complement(11818..12234)
                     /locus_tag="RHX21_003834"
     CDS             complement(11818..12234)
                     /locus_tag="RHX21_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HDV1988958.1"
                     /translation="MWYQKTLTLSAKSRGFHLVTDEILNQLADMPRVNIGLLHLLLQH
                     TSASLTLNENCDPTVRHDMERFFLRTVPDNGNYEHDYEGADDMPSHIKSSMLGTSLVL
                     PLHKGRIQTGTWQGIWLGEHRIHGGSRRIIATLQGE"
     gene            complement(12345..13058)
                     /gene="aphA"
                     /locus_tag="RHX21_003835"
     CDS             complement(12345..13058)
                     /gene="aphA"
                     /locus_tag="RHX21_003835"
                     /EC_number="3.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase AphA"
                     /protein_id="HDV1988959.1"
                     /translation="MRKITQAISAVCLLFALNSSAVALASSPSPLNPGTNVARLAEQA
                     PIHWVSVAQIENSLAGRPPMAVGFDIDDTVLFSSPGFWRGKKTFSPESEDYLKNPVFW
                     EKMNNGWDEFSIPKEVARQLIDMHVRRGDAIFFVTGRSPTKTETVSKTLADNFHIPAT
                     NMNPVIFAGDKPGQNTKSQWLQDKNIRIFYGDSDNDITAARDIGARGIRILRASNSTY
                     KPLPQAGAFGEEVIVNSEY"
BASE COUNT         3434 a         3451 c         3221 g         3122 t
ORIGIN      
        1 tgtattctcg atgactcaaa tttccctcag ataaaaatgg ccgacggaac tctaaatgca
       61 tgctccgcta tgcatgttca attctacaat gcagcaatga atagagccaa tattaaaaat
      121 acctttcttg actattcaaa tttttatatg gcgtacatgg ctgaggtaaa tctttataaa
      181 gtaatagcgc catatgttaa tttatttaaa gccgacctta gtttctctaa actcgattta
      241 attaactttg aacatgctga tctgtctcgc gtcaatctga acaaagcaat cctccagaat
      301 ataaacttaa ttgatagcaa actcttttgt acgtggctaa caaatacatt cctcgaaatg
      361 gttatatgta ccgactctaa tatggctaat gttaatttta ataatgccaa tttaagcaac
      421 tgccatttca actgttctat tttaacaaaa gcctgtatgt ttaatacccg tctctatcgg
      481 gttaattttg atgaggctag cgtccaggga atgggcattt ccatactccg tggggaggaa
      541 aatatcccca ttgatagtga taccctggta acacgacaga aattctttga agaagattgt
      601 acctctcata ctggcatgtc acaaactgag gataatatta atgcagtcgc tatgaagatt
      661 actgcagata ttatgcaaca cgcagattga ggttaaatcg aagaacagcc aatgaattga
      721 ctttacaaga gagataactt atttgtttta gaatcatgaa tgttagcccg agctaacctg
      781 ttaaaggtgc aaaagattgc acctttttca gattacctcg ggcctggtta cgtcgctttc
      841 ggcttactga ttttcctcaa ttagcaacgc ttcaagcaaa tcgagatcgt gcagtaattt
      901 ttgcagcgtt tcgttgctga tctcccgcgt ggcgcgcagg tggtacagtt cagcacgttc
      961 agaacgcaat gccgccagac ggaagcgacg ctcaaggttc tcttcctgca cggaactttc
     1021 aacgtcgtta cgtccatcgg cgcgacgacg caggttacca atgacgcgag aactgacctc
     1081 cgtaagcagc tggttatcga tattctcttc ggtatccgcc gccagacgct cctccatttt
     1141 ctggatcgcc acaatcgcca cttctgccgt tgccgctcgc gcaatacgtt cctctttcaa
     1201 ttgttgcgaa tgatccgcga cttcaatgtg ttgtagcaga ataggcaaca tcaccacgcc
     1261 gacaaacagc gagaagagaa tgacgccagc cgccaggaac accagctcat agcgcgccgg
     1321 gaagacgtta ccatccggca agagcagcgg gatagagagc acaccggcca gagtgatcgc
     1381 cccacgcacc ccagcgaaag acgcgatcag gatttctcgt gtggtccacg aaccaaactc
     1441 catcggcttc ttcttcagga agcggttgct gaactttttc atcgtccaca gccagccgaa
     1501 acggaccagc atcagcgccg catatatcag aataatatcg gtaaacagca tccagatttc
     1561 gacgttaggg tcgatttctg ccgccatcag cgacgtctcc agaatacccg gtagctgcag
     1621 acctaacagc aggaacacca tgccgttaaa gacaaattcc agcatcgccc aggtgctgtt
     1681 tgcacgcagg cgcattgcca gcggcgcacg gcgcatcaca ccggagcggg tgatggtcat
     1741 cccggcggca accgcagcga ggatgccgga aacgccaata tgttcggcaa tcagataaga
     1801 agcgaatggc agcaggaaca gcaggacgat ctgcgtcgcg ggttcatcac cgccccagcg
     1861 gctgaggaat cgcagcgagc gaccgtacag ccagctaacc acaaaaccgg cgagaatacc
     1921 gccaatggct actttcataa attcgaccgt cgcaccgccg acggtgaaga tcatcgtccc
     1981 catcgccact gctacggcaa acttcaacga caccaggccg gaagcgtcat tcatcaacgc
     2041 ttcgccctgc aaaatgccca tgattttttt cgggatacgc ccttcgccaa caatcccgga
     2101 gagcgccaca gcatcggtcg gagaaagtac cgccgccagc gcaaaggcgg ggatcagcgg
     2161 aatgcccggc accacccagt aaataaggaa gccaatgccg accacggtga ccaccaccag
     2221 cgccagcgcg aggccaaaaa tctctcgacc atgttcgaga aattcacggg tcggcgtttt
     2281 ccagccatca gcgaacagca acggcgggat aaacaagact aaaaagagtt caggatcaaa
     2341 ctccacatgc aaaccaaacg tcggccacgc cagtagcgca ccgatggcga tttgcataag
     2401 cggaagcggg atctgaaagg gcatgacacg agtgaccacc ccggacagcg agaccacgag
     2461 ggtcattatc agtatggtga agaagatttc catgcgttcc ctgtttgcga tgttttttat
     2521 gatctgagaa agacgttatg cctgaattct cattttttca gaatatcgca aaagctcaca
     2581 caatgtgcgg agaaaataaa aacgggcagc cattgccacc cgttttcaga atccgatgaa
     2641 agattagata gcccagccac ccgcatagaa ggtcaccagc gccacggcga taacgaccgt
     2701 accgatgttc aacttgcgcc attcgccgga aaccagacga ccaatcacca gagtcgcgaa
     2761 gccgatcatg atgcctgtta cgatgttaca ggtcagcacg atgaataccg ccgtaaccag
     2821 acccgccatc gcatcaacaa aatcagcaaa gtcgattttc gccacgttgc tcagcatcag
     2881 caggccaacg tacatcagcg ccggagccgt tgcatacccc ggaacgaggt aagagagcgg
     2941 agagaggaac agaatcagca ggaacagcac gccaacggtg atagccgtca aaccggtttt
     3001 accgcccgcc gccgtacccg ccgcagactc gatgtatacc gctgccggag ctgcacccac
     3061 caggccagag aaaacgctgc tcatggagtc agtggtcagt gctttcccac cgtcgatgat
     3121 ctgcccatct ttatccagca ggttcgcctg gccggcgacg gcacggatag ttccggtggc
     3181 atcaaatact gccgtcatca ccagcgccag aacgcttggc aggactacag gattcagcgc
     3241 gcccataatg tccaggctgc caatcagtga attgccgttt tcatcgctca atgaaggcat
     3301 ggcgaaaacg ccggagaaat ggacgttagg atcgaagatc aaaccgacaa ttgagatacc
     3361 gataatggtc agcagaatgc caccagggac tttcagtttt tccaggccga tgatcaccgc
     3421 cagacctacc agtgacataa tcaccgggaa ggtcgcgaaa tcacccagcg caacgggcag
     3481 accatcaagc gggtttttaa tcaccagacc gacaccatta gcggcaatga gcagcaggaa
     3541 cagaccgata ccgatccccg tgccgtgcgc cacaccgtga ggcaagttgc gcaaaatcca
     3601 gctacggata cccgtggcag aaattaccgt aaacagcaca cccatcagga acacggcacc
     3661 cagcgcgaca ggtacgctaa tatgttgccc cagcaccagg ctgaatgcgg taaatgccgt
     3721 cagggagatg gcgcaaccaa tcgccaacgg cagattagcc cacagaccca tcacgataga
     3781 accgagtccg gcaaccagac aggttgcaac gaaaactgcc gcaggcggga agcctgcttt
     3841 acccaacata cctggaacga cgatgaccga gtagaccatc gccagaaacg ttgttaaccc
     3901 ggcaaccact tcctgacgga cagtgcttcc acgttgtgaa attttaaacc aggcgtcgag
     3961 tgaaccgccg gtacgcgctg atggcgtaga cataagaaaa catcccctga gagtttaatt
     4021 ttcgtcaaga tgcgtggcgg acaatcccct gccagcgaaa cgttatcttc ctgctccagg
     4081 tttgcgacaa tttgctgcgt cgcaaaaaag caaacgttta gctccgcgca tacaaaacgg
     4141 gtggtaaaaa aagcaaacga ttatccggcg atcatagcgg ctttttcaac cgaagtttgc
     4201 tgcttttttc tcttttattg tcttgacgat gaaaaaccag gcaattgatg cgcaaacgtt
     4261 atcgtcggtg cgcaagattg cagcgttatc gagccgtata ccgttcagga ttgcgataaa
     4321 aaatcgtctg agatgacaaa aatattgcgg ttaaaaagta tacttttaca ctggcgaaga
     4381 aacgtcggtg acatacaatt aaagcatcaa caccaaccgg aacctccacc acgtgctcga
     4441 atgaggtgtg ttgacgtcgg gggaaaccct cctgtgtacc agcgggatag agagaaagac
     4501 aaagaccgga aaacaaacta aagcgccctt gtggcgcttt agttttgttc atcttccagc
     4561 aagcgtgcgc cggtaccttc ttctcctaag cggtcgcccg ggttacgcaa cgggcaatca
     4621 ctgcgcgaaa ggcagccaca accaatacat ccgtccagtt cgtcacgcag cgctactaag
     4681 gtatgaatgc gccgatccaa ctcttctcgc cattgggacg aaagctgttt ccactctttc
     4741 gcacttaacg tatgcccttc gggcaacacg ccaaacgctt caccaatggt cgccagcgga
     4801 atgccaatac gctgagcaat tttgataatt gcaacatatc gcaacacatc acgtttatat
     4861 cgccgctgat tgccgctgtt acggatactg gtaatcaacc ctttactttc atagaaatgc
     4921 agcgccgata ccgccacacc gctgcgtttc gccacttcgc cgggggttag cagcgcttta
     4981 atgcggggta atttcttttc cataaatcgc tttacctcaa gttaacttga ggaattatac
     5041 tccccaacag atgaattaac gaactgaaca ctgaaaagag gcagatttat gtcccatcag
     5101 aaaattattc aggatcttat cgcatggatt gacgagcata ttgaccagcc gcttaacatt
     5161 gatgtagtcg caaaaaaatc aggctattca aagtggtact tgcaacgaat gttccgcacg
     5221 gtgacgcatc agacgcttgg cgattacatt cgccaacgtc gcctgttact ggccgccgtt
     5281 gagttgcgca ccaccgagcg tccgattttt gatatcgcaa tggacctggg ttatgtctcg
     5341 cagcagacct tctcccgcgt tttccgtcgg cagtttgatc gcactcccag cgattatcgc
     5401 caccgcctgt aattttattg cccgcgcgtt aactcccgcg cgggtaattg ctccatccat
     5461 tgcataaaca cctgcggcgg catcgccttc gcaaagaacc atccctggca atagcgcacg
     5521 ccgcgtttgc gcagccagtt aacctgctcc tcagtttcga cgccttcagc gatcgttttt
     5581 aaccccaggc tgtgcgccag ctcgatgatg tgttccgcaa tcaaatgact ggttttgtgg
     5641 gtggtcagcg tttcaacaaa cgatttgtcg attttcaaaa tatcgacatt caatgattta
     5701 aggttatgca agttagagta gccaatacca aaatcatcaa ttgccacttc gtaaccagcc
     5761 tggcggaaag ccagaataat cggcgtcatt ttttcgacat caagaaatgc atgctcagtc
     5821 acttcaaatt taatttgctg cggacgcacc gcgtattgct ctgttttctg attgattcgc
     5881 gctatcaacc gtgacgtatg aaaatcggag gccgacaggt taatagaaac atagcgatct
     5941 gcatgtgttg ccaggtaatc gcccagatcg cggaagacat tatcaataac ataatcagtt
     6001 atctgttcta tcatcccctc cttttctgcc agcggaataa actctgccgg attcattatt
     6061 tgcccctgct caccaagcca acgtaacaac gcttcagcgc cgatacattt ttctgttttg
     6121 atatcgatta ttggctggta ataaagacaa agttgatgtt tttcgagggc gcgttgcaat
     6181 ttacgtttgg gagataaata gttttgtcga atacgtagcc agagtaatag cagaacaaga
     6241 ctccccaaaa taccggcggg caacgcaaaa ataagatgat tataaaaatg ggttataaga
     6301 cgttgatatg aagtcgcaac aatggctgca attgggcgtt ttgtcgaata aactgtcgca
     6361 tataaatagc catttctttg tacggttaaa tccttcaaat gaatcagcgg agaaaacgtt
     6421 gctgccgagg cctctttgct taacgagaaa aaggttttcg tcaccgtatc atacacaccc
     6481 cattgcaatg tcggatcatc agacatcact tcactccaga agagagggtt gataaccgcc
     6541 acataatttc cccgctgcat ataggtcatt ttatagccag agaaaaaagg cgtatcgcgg
     6601 taataataga tagaaacgtt aggttcacgc ttataatcgg ccggtgcaat cgtatagccg
     6661 tttacaggcg ctatcagcga tgagcataaa aaatggttat cacgggcata gatcaattca
     6721 ttaatataaa gatagccacg aataatattc aacattcgct tttgatgggc tggagtgcaa
     6781 acttgcccct gatagcgttc agctgcatcg ctcactaaat ctgcctggcg aatgaccagc
     6841 tcggatttat ccagtgccag ttgagcaaag gttcggagct gattattcac ttctgatttt
     6901 gcccaaagga aggcaatcca tagcgaaaga atgatgggaa agagaactaa aaagataatg
     6961 cccggcaacg ccagtaattg gtgtcgtgca cgatgactca ttgctatcaa tttcctgcct
     7021 gtttataccc ggccattgca aggtgaaaac cctgggtacc gacgtcttta gataaatctt
     7081 acggtataaa tagcactttt gcctgatttg aaattgatac ctttctaatc gtcacctgga
     7141 tgaaaataat tcattgatat tcaaaattaa tttcctacag gaatgcagag gcggcgggaa
     7201 gatatgccct taatgccact gaaaaaccac ataatctgta cagcaataaa agtcacggcc
     7261 taatatggct aacaaacaat caattgtgat atagttcaca aaattaatga aacaaacaga
     7321 gtgtttcatt tttgtgttct gcaagccccg cgatagccag agtgtaccac gcctcccgtg
     7381 aacaacgccg cgctgtccag ggcatcggct cttttcagag gaattgtttg atggctaccc
     7441 tcaccactgg cgtggttctt cttcgctggc aacttcttag tgccgtaatg atgtttctgg
     7501 ccagcacact caacatccgt tttcgtcggt ctgattatgt cgggcttgcg gtgatcagca
     7561 gcggtctggg cgttgtttcc gcctgttggt tcgcaatggg gttgcttggc atcacaatgg
     7621 cggacatcac cgctatctgg cacaacatcg agtcggtgat gatagaagag atgaatcaga
     7681 caccgccaca atggccaatg attttgacct gatacgtaga agcctccata acggaggctt
     7741 cttttttatg gctggcagat gctttaatca tccaccttaa aacaatataa cctattgttt
     7801 taatgacaaa tcagaacgga atgtcatcat caaagtccat cggcggctcg ttagacggcg
     7861 ctgccggagc ggactgctgc gggcgagact gcgcgccgcc gctgaactga ttgccaccct
     7921 gcggctgctg tggctgaccc caaccgccct gcggctgacc accaccgata ttgccacctg
     7981 ccggagcgcc accaccctga cgaccaccca gcatctgcat ggtgccgcca acgttcacca
     8041 cgacttctgt ggtgtagcga tcctgaccgg attgatcggt ccatttacgg gtacgcagct
     8101 gaccttcgat ataaacctga gaacctttac gcagatattc gctcgccact tctgccagtt
     8161 tgccgaacag cacaacgcgg tgccattcag tctgttcttt catctcgccg gtcgctttat
     8221 cacgccagga ttcggaagta gccagcgtaa tgttggcaac tgcgccacca tttggcatgt
     8281 agcgtacttc cgggtcctga cccagattac caacgagaat aaccttgttt acgcctctgc
     8341 tggccatgtt cgtgtctcct gaaaaaaatc gttctgaata agtgtaaacg cgcgattgta
     8401 ccattaccaa tagcgctttt actatgttgt gacctcggtt ccgggaaaca aacctggcca
     8461 gacattgtta cacaacactc cgggtaatgc attccaatac tgtatattca ttcaggtcaa
     8521 tttgtgtcat aattaaccgt ttgtgatcgc cggtagcacc atgccaccgg gcaaaaaagc
     8581 gtttaatccg ggaaaggtga atggataaga tcgaagttcg gggcgcccgc acccataatc
     8641 tcaaaaacat caacctcgtt atcccccgcg acaagctcat tgtcgtgacc gggctttcgg
     8701 gttctggcaa atcctcgctc gctttcgaca ccttatatgc cgaagggcag cgccgttacg
     8761 ttgaatccct ttccgcctac gcgcggcagt ttctgtcact gatggaaaag ccggacgtcg
     8821 atcatattga ggggctttct cctgccatct caattgagca gaaatcgacg tctcataacc
     8881 cgcgttctac ggtggggaca atcaccgaaa tccacgacta tttgcgtttg ttgttcgccc
     8941 gcgtcggcga accgcgctgt ccggaccacg acgtcccgct ggcggcgcaa accgtcagcc
     9001 agatggtgga taacgtgctg tcgcagccgg aaggcaagcg tctgatgctg ctcgcgccaa
     9061 tcattaaaga gcgcaaaggc gaacacacca aaacgctgga gaacctggca agccagggtt
     9121 acatccgtgc tcgtattgat ggcgaagtct gcgatctttc cgatccgccg aaactggaac
     9181 tgcaaaagaa acacactatt gaagtggtgg ttgatcgctt caaggtgcgt gacgatctta
     9241 cccaacgtct tgcggagtcg tttgaaaccg cgctggagct ttccggtggt acagcggtag
     9301 tggcggatat ggacgacccg aaagcggaag agctgctgtt ctccgccaac ttcgcctgcc
     9361 caatttgcgg ctacagtatg cgtgaactgg agccgcgact gttttcgttt aacaacccgg
     9421 caggtgcctg cccgacctgt gacggccttg gcgtacagca atatttcgat cctgaccgcg
     9481 tgatccaaaa ccccgagctg tcactggctg gcggtgcgat ccgtggctgg gatcgccgca
     9541 acttctatta tttccagatg ctgaaatcgc tggcagatca ctataagttc gacgtcgaag
     9601 cgccgtgggg cagcctgagc gcgaacgtgc ataaagtggt gttgtacggt tctggcaaag
     9661 aaaacattga attcaaatac atgaacgatc gtggcgatac ctccatccgt cgtcatccgt
     9721 tcgaaggcgt gctgcacaat atggagcgcc gttataaaga gacagaatcc agtgcggtac
     9781 gtgaagaatt agccaagttt atcagcaatc gcccatgcgc cagctgcgaa gggacgcgtc
     9841 tgcgtcggga agcgcgccac gtttatgtcg agaatacgcc gctgcctgct atctccgaca
     9901 tgagcatcgg tcatgcgatg gaattcttca acaatctcaa actagctggt cagcgggcga
     9961 agattgcaga aaaaatcctt aaagagatcg gcgatcgtct gaaattcctc gttaacgtcg
    10021 gcctgaatta cctgacactt tcccgctcgg cagaaacact ttccggcggt gaagcccagc
    10081 gtatccgtct ggcgagccag attggtgcgg gcctggttgg cgttatgtat gtactggacg
    10141 agccgtctat cggcctgcac cagcgcgata acgagcgcct gttgggtacg cttatccatc
    10201 tgcgcgatct cggtaatacc gtgattgtgg tggagcatga cgaagacgca attcgcgccg
    10261 ctgaccatgt gatcgatatc ggtcctggtg cgggtgttca cggcggtgaa gtggtcgcag
    10321 aaggtccgct ggaagcgatt atggcagtgc ctgaatcgtt gaccgggcag tacatgagcg
    10381 gtaaacgcaa gattgaagtg ccgaagaaac gcgttccggc gaatccagaa aaagtgctga
    10441 agctgacagg tgcacgcggc aacaacctga aggacgtgac gctcacgctg ccagtcggtc
    10501 tgtttacctg catcacaggg gtttcaggtt ccggtaaatc gacgctgatt aacgacacac
    10561 tgttcccgat tgcccaacgc cagttgaatg gtgcgaccat cgccgaaccg gcaccgtatc
    10621 gcgatattca ggggctggag catttcgata aagtgatcga tatcgaccaa agcccaattg
    10681 gtcgtactcc acgttctaac ccggcgacct ataccggcgt gtttacacct gtgcgcgaac
    10741 tgtttgcggg cgtaccggaa tcccgtgcgc gtggttatac gccaggacgt ttcagcttta
    10801 acgtccgtgg cgggcgctgc gaagcctgtc agggcgacgg tgtgatcaaa gtggagatgc
    10861 acttcctgcc ggatatctac gtgccgtgcg atcagtgcaa aggtaaacgc tataaccgtg
    10921 aaacgctgga aattaagtac aaaggcaaaa ccatccacga agtgctggat atgaccatcg
    10981 aagaggcgcg tgagttcttt gatgcggtgc cagctctggc gcgtaagctg caaacgttga
    11041 tggacgttgg tctgacgtac attcgcctgg ggcagtccgc aaccacactt tctggtggtg
    11101 aagcccagcg cgtgaagctg gcgcgtgagc tgtcaaaacg cggcaccggg cagacgctgt
    11161 atattctcga cgagccgacc accggtctgc acttcgccga tattcagcaa ctcctcgacg
    11221 tgctgcataa actgcgcgat cagggcaata ccattgtggt gattgagcac aatctcgacg
    11281 tgatcaaaac cgctgactgg attgtcgacc tgggaccaga aggcggcagt ggcggcggcg
    11341 aaatcctcgt ctccggtacg ccagaaaccg tcgcggagtg cgaagcttcg catacggcac
    11401 gcttcctcaa gccgatgctg taatcgttaa ggccgctttc tgagcggcct tttcctttca
    11461 gagttgtacc agcaatttac gcttttcttc cggtagtaaa ttcactgcct gctgataaga
    11521 cgcatccacc agataataga tttgcgaatc cggcagcgaa ccgtcgagat acacggtgct
    11581 ccagtgcgct ttattcagat ggcggctagg acgcacatcg ctgtgctgct gacgtagcag
    11641 ctccgccagc tccgggctgg ttttcagcga aacagctggg cgattttcta cttctttcac
    11701 catcgcaaac agtacatctt ccactttgat ctgcgtcgct ttccagtcgt tatgcacgct
    11761 ctgttctgcg cctggttttg ccatgcaata ttgtagcaac tccgaaatgg tcatttttta
    11821 ctccccttgt agtgtcgcga tgatgcgacg cgatccgccg tggatgcgat gttcccccag
    11881 ccagatgcct tgccaggtgc cggtctgaat acgcccttta tgtaacggca atacaagcga
    11941 tgttcccagc attgaggatt tgatatgaga aggcatatcg tctgctccct catagtcatg
    12001 ctcataattt ccgttgtcgg gaacggtgcg gaggaaaaaa cgctccatgt cgtggcgtac
    12061 ggtgggatcg cagttctcat taagtgtcag agaggcggag gtatgttgca gcaacagatg
    12121 cagtaagccg atgttaacgc gcggcatatc agccagctga ttcagaattt catccgttac
    12181 cagatgaaac ccacgagatt tggcgctaag cgtgagcgtc ttttgatacc acatgtgctg
    12241 ctccttgata aaactctctt aatcagtttg cagcaagaca gcgaaaggat aaaggtgtga
    12301 ttaaaaaaac agcattcggg agagcatcac gctctcccgc tctgtcagta ttctgaattg
    12361 acgatcacct cttcaccaaa cgcacccgct tgtggcaagg gtttgtaggt agagttggag
    12421 gcgcgcagaa tgcggatacc acgagcgccg atatcgcgtg cggcggtaat atcgttatcg
    12481 gaatcgccat aaaaaattcg gatattttta tcctgcagcc attgcgattt tgtattttgc
    12541 cctggtttat cgcccgcaaa gattactgga ttcatgttgg tggcaggaat atgaaaatta
    12601 tccgccagcg tttttgaaac cgtttctgtt ttcgtcgggc tacgaccagt cacaaagaag
    12661 atcgcgtcac cgcggcgtac atgcatatca atcagctggc gagcgacctc ttttggaatg
    12721 ctgaattcat cccagccatt gttcattttt tcccagaaca caggattttt cagataatct
    12781 tcgctttctg gtgagaaggt ttttttgccg cgccagaagc ccgggctgga aaaaagtacc
    12841 gtgtcatcga tatcaaaccc caccgccatt ggcggacgcc ctgcgaggct attttcaatt
    12901 tgtgcgaccg aaacccaatg aattggtgcc tgttcagcaa gcctggcaac gttagtccca
    12961 gggttaagcg gtgaaggaga tgaggccagg gcaacagcgg aactgtttag agcgaacaat
    13021 aagcaaacgg cactgattgc ctgtgtgatc ttgcgcatat ttttccctaa atagtcagta
    13081 tgttgaaact ttttattgtg agatttgttg caaaaaccat ctgaccataa cgccagctgc
    13141 cggggaaagg aaggattatc tgcggttttt gtgatgaaaa gcaggatgat tatatttaac
    13201 ccagtaaata cgttcctgtc tttttttg
//
LOCUS       DAPGUL010000125        13142 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.127, whole genome shotgun sequence.
ACCESSION   DAPGUL010000125 DAPGUL010000000
VERSION     DAPGUL010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13142
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.127"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            425..775
                     /locus_tag="RHX21_003836"
     CDS             425..775
                     /locus_tag="RHX21_003836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001135225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDV1988960.1"
                     /translation="MPPRTPKACRVRGCRFTTTDPSGYCESHKSEGWKQYKPGQSRHQ
                     RGYGSKWDSIRARVLKRDKGLCQLCLRAGVVREAKTVDHIIPKSHGGTDVDSNLQSLC
                     WPCHKAKTARERLK"
     gene            901..1395
                     /locus_tag="RHX21_003837"
     CDS             901..1395
                     /locus_tag="RHX21_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HDV1988961.1"
                     /translation="MAGTAGRSGRRPKPTARKALAGNPGKRALNKDEPVFTPIKGVEP
                     PEWFAEEDLPLATIMWQLTTKELCGQGLLCVTDLAVLERWCVAYEFWRRAVKNIARQG
                     NTITGAMGGMVKNPELTAKKEQESEMSSTGAMLGLDPSSRQRLIGLAGQKKATNPFLK
                     IIES"
     gene            1629..3125
                     /locus_tag="RHX21_003838"
     CDS             1629..3125
                     /locus_tag="RHX21_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HDV1988962.1"
                     /translation="MPITLEPWQLFVICCAFGWVNKGTRLRRFREVYTEIPRKNGKSA
                     ISAGVALYCFACDNEFGAEVYSGATTEKQAWEVFRPARLMCKRTPMLTEAFGIEVNAS
                     NMNRPEDGARFEPLIGNPGDGSSPHCAVVDEYHEHATDALYTTMLTGMGARRQPLMWA
                     ITTAGYNIEVPCYDKRREVLEMLNGSVPNDELFGIIYTVDEGDDWTDPQVLEKANPNI
                     GVSVYREFLLSQQQRAKNNARLANVFKTKHLNIWVSARSAYFNLVSWQSCEDKSLTLE
                     QFEGQPCILAFDLARKLDMNSMARLYTREIDGKTHYYSVAPRFWVPYDTVYSVEKNED
                     RRTAERFQKWVEMGVLTVTDGAEVDYRYILEEAKAANKISPVSESPIDPFGATGLSHD
                     LADEDLNPVTIVQNFTNMSDPMKELEAAIESGRFHHDGNPIMTWCIGNVVGKTIPGND
                     DVVKPVKEQAENKIDGAVALIMAVGRAMLYEKEDTLSDHIESYGIRSL"
     gene            3137..3319
                     /locus_tag="RHX21_003839"
     CDS             3137..3319
                     /locus_tag="RHX21_003839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988963.1"
                     /translation="MIMLILAPLVGVLGALLLAYGAWLIYPPAGFVVAGALCLFWSWL
                     VARYLDRTQSSAGGGK"
     gene            3319..4560
                     /locus_tag="RHX21_003840"
     CDS             3319..4560
                     /locus_tag="RHX21_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDV1988964.1"
                     /translation="MFFSGLFQRKSDAPVTTPAELADAIGLSYDTYTGKQISSQRAMR
                     LTAVFSCVRVLAESVGMLPCNLYHLNGSLKQRATGERLHKLISTHPNGYMTPQEFWEL
                     VVTCLCLRGNFYAYKVKAFGEVAELLPVDPGCVVPKLNSSWEPVYQVTFPDGSTDVLS
                     QEDIWHVRTLTLDGLVGLNPIAYAREAISLAAATEEHGARLFSNGAVTSGVLRTEQTL
                     SDQAYERLKKDFEERHTGLGNAHRPMILEMGLDWKSMALNAEDSQFLETRRFQLEEIC
                     RLFRVPLHMVQNTDRATFNNIEELGLGFINYSLVPYLTRIEQRINTGLVRKSKQGVYY
                     AKFNAGALLRGDMKSRFEAYATGINWGIYSPNDCRDLEDMNPRPGGDVYLTPMNMTTK
                     PSDGSKAGKQKDNANADETTS"
     gene            4538..5188
                     /locus_tag="RHX21_003841"
     CDS             4538..5188
                     /locus_tag="RHX21_003841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HDV1988965.1"
                     /translation="MQTKQRLDVPLSLKSVSDSGEFEGYGSVFGVKDSHDDVVMSGAF
                     AASLRAWSDRKALPALLWQHRMDEPIGVYTEMKEDDVGLYVRGRLLIDDDPLAKRAHA
                     HMKAGSLTGLSIGYVLKDWEYDRTKEAFLLKEIDLWEVSLVTFPSNDEARISDVKNAL
                     ARGEIPEQKKIERVLRDVGLSRTQAKAFMAGGYGALSLRDAEDVGSALNALKNLNF"
     gene            5203..6408
                     /locus_tag="RHX21_003842"
     CDS             5203..6408
                     /locus_tag="RHX21_003842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HDV1988966.1"
                     /translation="MAVDIKDVEQVAQELQQKFDDFKAKNDKRVDAIEQEKGKLAGQV
                     ETLNGKLSELENLKSDLEKELLELKRPAGGAQNKLATEHKEAFVGFLRKGREDGLRDL
                     ERKALQVGTDEDGGYAVPEALDRNILNLLKDEVVMRQEATVITVGGSDYKKLVNLGGT
                     ASGWVGETDTRSQTATSRLELIEPLMGEIYGNPQATQKMLDDAFFNVEAWINSELATE
                     FAEQEEIAFTTGDGTKKPKGFLAYESTDETDKVRAFGKLQHIVSGDATAVTADAIIKL
                     IYTLRKAHRTGAKFMMNNNSLFAIRLLKDTEGNYLWRPGLELGQPSSLAGYGIAENEQ
                     MPDIAADAKAIAFGNFKRGYTIVDRIGTRILRDPYTNKPFVGFYTTKRTGGMLVDSQA
                     IKLLKIAAA"
     gene            6458..6658
                     /locus_tag="RHX21_003843"
     CDS             6458..6658
                     /locus_tag="RHX21_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001735262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988967.1"
                     /translation="MILKQDLKWSPDGMRVEVIRAGEYDDGALPARVQEIALQAGLAE
                     RGTSAKSSKAAKEKKATTSKEG"
     gene            6661..6984
                     /locus_tag="RHX21_003844"
     CDS             6661..6984
                     /locus_tag="RHX21_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001492759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HDV1988968.1"
                     /translation="MLLTIEEIKAQLRLDEDFDTDDRHLQLLACAAQKRTETYLNRKL
                     YAPDETIPDSDPDGLHLPDDIRLGMLMLISHFYENRSSVTEVEKLDMPQSFGWLVSPY
                     RYFPQ"
     gene            6981..7391
                     /locus_tag="RHX21_003845"
     CDS             6981..7391
                     /locus_tag="RHX21_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HDV1988969.1"
                     /translation="MKIRQAQTSATYILPDPGELNKRVLIRQRVDMPADNFGVEPQYP
                     VAFRAWAKVIQTSATTWQETAQTGDAITHYITIRYRRGITADYEVVCGDSVYRVKRQR
                     DLNGARRFLLLECTELGEFTQSHGGNNGDFLFAR"
     gene            7366..7872
                     /locus_tag="RHX21_003846"
     CDS             7366..7872
                     /locus_tag="RHX21_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001501060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988970.1"
                     /translation="MATSFLHVDFQQPAEMRFNRARVRRAFVTIGQRHMRDARRLVMR
                     RVRSAPGENPGYQTGRLARSIGYMVPRASKHRPGFMARIAPNQRNGEGNRRITGDFYP
                     AFLFYGVRRGAKRRRSHHRGASGGSGWRLAPRNNFMVETLEKNRSWTRYFLARELRKS
                     LKPERRHR"
     gene            7869..8429
                     /locus_tag="RHX21_003847"
     CDS             7869..8429
                     /locus_tag="RHX21_003847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988971.1"
                     /translation="MKLTPVIAALRARCPYFENRVAGAAQFKNLPEVGKLKLPAAYVV
                     PGDDSPGENKSQTDYWQELKEGFSVVVILSNGRDERGQFASYDVVDDVRQMLFKALLG
                     WNPEACGNPITYDGGTLLDLNRHELIYQFDFSVISELTEDDTRQQDDLNSLDELQTLA
                     IDVDYLDPGNGPDGDIEHHTEITLPS"
     gene            8438..8608
                     /locus_tag="RHX21_003848"
     CDS             8438..8608
                     /locus_tag="RHX21_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000497758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2635 domain-containing protein"
                     /protein_id="HDV1988972.1"
                     /translation="MFVKPVKGRSVPDPARGDLLPTEGRNVDENNYWLRREAAGDIRR
                     VNKKVNTDDDKL"
     gene            8592..10088
                     /locus_tag="RHX21_003849"
     CDS             8592..10088
                     /locus_tag="RHX21_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath subtilisin-like
                     domain-containing protein"
                     /protein_id="HDV1988973.1"
                     /translation="MTISFNTIPSNTLVPLFYAEMDNSAANTVQDSGASLLIGHANNG
                     AEIVANSLVLMPSADYARQICGAGSQLARMVEAYRQTDPFGELYVIAVPEATGAAATV
                     TLTVTGAATETGTVNVYVGRTRVQTPVTNGDNVTTIASSIKDAINAVPALPFTASSSA
                     GVVTLTARHKGLCGNEIPVSLNYYGFGGGEVLPAGVQIAVATGTAGTGAPVLTGAVAA
                     MADEPFDYICLPFNDTASVNTLVTEMNDTSGRWSYARQLYGHVYTAKTGTLSELVTAG
                     DQFNQQHITLAGYEKDTQTPADELAASRTARAAVFIRNDPARPTQTGELVGMLPAPKG
                     KRFTMTEQQTLLSHGVATAYVESGVLRIQRDVTTYRKNAYGVADNSYLDSETLHTSAY
                     VLRKLKSVITSKYGRHKLASDGTRFGPGQAIVTPAVIKGELLATYRQLERAGIVENYE
                     LFKQYLVVERDASDPNRLNTLFPPDYVNQLRVFAVVNQFRLQYSEESA"
     gene            10088..10444
                     /locus_tag="RHX21_003850"
     CDS             10088..10444
                     /locus_tag="RHX21_003850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tube protein"
                     /protein_id="HDV1988974.1"
                     /translation="MARIGGTCYFKIDGQQLSLTGGIEVPMNRTVNDDIIGLDGSVDR
                     KETHRAPYVKGTFKVPKNFPVSKITSSDEMTITAELANGQVYVLSSAWLHGEANHNAE
                     EGTVDLEFHGEEGDYQ"
     gene            10444..10713
                     /locus_tag="RHX21_003851"
     CDS             10444..10713
                     /locus_tag="RHX21_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001526907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein"
                     /protein_id="HDV1988975.1"
                     /translation="MKELELKKPITAHGETLSVLEFDEPTGKDVRELGYPYQMNQDES
                     VRLLAHVVSKYIVRLAKVPQSSVDQMSPADLNAAAWLVAGFFLQA"
     gene            10855..12687
                     /locus_tag="RHX21_003852"
     CDS             10855..12687
                     /locus_tag="RHX21_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDV1988976.1"
                     /translation="MAEFELKALITGVDRLSPALSKMQKKIRGFKRQAEEASQGGLAL
                     GGGLAAGLTLSLKSYADQENAATGLKVAMMDANGEVGKSFQDINKLAIGLGNQLPGTT
                     ADFQNMMQMLVRQGIPAENILGGVGKATAYLAVQLKKTPEAAAEFAAKMQDATGTASE
                     DMMGLFDTIQKAFYLGVDDTNMLSFFTKTSSVLKMVNKDGLQAAQSLAPISVMMDQMG
                     MNGESAGNALRKVIQSGLSVKKIRDVNKVMARQKLGVQLDFTDGKGSFGGLDNMFKQL
                     AKLRKLTDVKRTGVLKAIFGDDAETLQVVNALIDKGKDGYDQIQQKMNKQASLNKRVQ
                     AQLGTLSNLWEAMTGTATNGLAAIGGAFSGDAKNITQWLGELGEKFTKFADENPRVIR
                     GVVGLAAGLAILKLGLMGVGGAISIVSRIMSMTPIGMIATAIALAAGLIITNWDVVGP
                     YFKKLWETIGPYFEAGWELLKKVFAWSPLGIVINNWGPVVKWFQDMWDKLKPIIEWFT
                     DSSGDTVDAINSAQWGAGAYDAYGTGIPARGYTPYPAVDPAQSNNASDATGPNPFMIN
                     KAIAPKVDGEIKVSFMNMPPGMRVTETRSSGIDINHDVGYTRFR"
     gene            complement(12720..>13142)
                     /locus_tag="RHX21_003853"
     CDS             complement(12720..>13142)
                     /locus_tag="RHX21_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000734912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1988977.1"
                     /translation="LYIFIGLVIIGYFAGNNDKGSNSSYSSDTEAAAPQKEIYNTTAR
                     QLFKQYEENEVATDEQLKGKLIAVRGIVQSIDKDFTDSIIIKFRTENEFMPARMEMQD
                     SEKSTAAALKKGEQVTVICEKMSRIVGSPSGRNCVFAQ"
BASE COUNT         3148 a         3253 c         3861 g         2880 t
ORIGIN      
        1 tcagactatt ggaggtagtc aggatttgaa tgtcagtctg ttgtcggcat tctggcaatg
       61 caatttggat aaagcgggga ttaaaaagat agaggcgagc cggtcaggta gaaatgaatc
      121 aggctcaaat tgaagcggaa aaggtctgtg gcacaaactg atgctgccat aattacagcc
      181 tgatgacttg tggaatgaaa catgttgaac ctccttaatt gatgtgattc gagtgaggaa
      241 ggcattctgt ccctctatag tgtccattaa atcaaacggg aaatttgtct catgcgtgag
      301 acaagtctct ccattagtga gttgtattga ttgcgactct tcaaagaatc cattactgcg
      361 ttgatgaaaa aggtttacta cgaatgaagg cagctatttc gctggtttct tcattggagt
      421 acatatgccc ccacgaaccc caaaagcctg ccgtgttcgc ggctgccgct ttacaaccac
      481 ggacccttca ggctactgcg aaagccacaa aagcgaaggc tggaagcaat acaaacctgg
      541 acaatcccgt catcagcgcg gctacggttc gaagtgggac agtatccgcg cgcgtgtcct
      601 gaagcgtgac aaaggcctgt gtcagttatg tctgcgtgct ggtgtggtgc gtgaggcgaa
      661 gaccgttgac cacatcatcc ctaaatcgca tggcggcact gatgtcgaca gtaatctgca
      721 gagtttgtgc tggccgtgtc ataaggcgaa gacggcccgt gaacggctga agtaagaacc
      781 agttcccact gccagagggg aggggcgggt caaatccctg tgacctgacg tcttctggac
      841 tgcccgcccc atcgtttttt tatacccgcg aaaaatgaaa tttaaccagg agtgccgcat
      901 atggctggaa cggcggggcg ttccgggcgt cgccccaagc caacggcgcg caaggcgctg
      961 gccggaaacc ccggcaagcg agccctgaat aaagatgaac ctgtttttac gcccatcaaa
     1021 ggtgttgagc caccggagtg gttcgctgaa gaagatctcc ctctcgccac gatcatgtgg
     1081 caactgacaa ccaaagaact ctgcggtcag ggcctgctgt gcgtgactga cctcgcggtg
     1141 cttgagcggt ggtgtgtggc ctatgagttc tggcgacgtg ccgtgaaaaa tattgccaga
     1201 cagggcaaca ccatcaccgg tgcaatgggc ggtatggtca aaaatcctga gctgaccgcc
     1261 aaaaaagaac aggagtccga gatgagcagt acgggggcaa tgctcggact cgaccccagc
     1321 agccgccagc gtctgattgg cctggcgggg cagaagaaag ccactaaccc gtttctgaaa
     1381 attatcgaat catgagccgg aaatcttatc ccaacgtaaa tgctgccaat cagtatgccc
     1441 gggatgtcgt tcgcggaaag attgtggcct gccagtttgt gattcaggcc tgccagcgcc
     1501 atcttgatga cctgatggcg gaaaaaagta agtcgtttcg ttaccgcttc gacaaggacc
     1561 tggctgaacg ggccgccaaa tttattcagc tgttgccgca taccaagggt gagtgggcat
     1621 tcaaacggat gcccatcacg ctggagccgt ggcagctctt tgtgatctgc tgtgcgtttg
     1681 gctgggtcaa taaaggtacc cggctgcgcc gcttccggga ggtgtatacc gaaatccccc
     1741 gtaagaacgg caaatcggca atctctgccg gtgtcgccct gtattgtttt gcctgtgata
     1801 acgagtttgg cgcggaagtg tattccggtg ccacgacaga gaaacaggcg tgggaagtct
     1861 ttcgcccggc gcgactgatg tgtaaacgca cacccatgct gacggaagcg ttcgggattg
     1921 aggttaacgc ctcaaacatg aaccgtccgg aggatggcgc gcggtttgag ccgctgatcg
     1981 gtaaccccgg tgatggttca tcaccccact gtgcggtggt ggatgaatat cacgagcatg
     2041 ccaccgatgc actttacacc acgatgctta ccgggatggg ggcgcgacgt cagccactga
     2101 tgtgggccat caccaccgcc gggtacaaca ttgaggtgcc gtgctacgac aagcggcggg
     2161 aagttctcga gatgctcaac ggttcggtac ccaacgatga actgttcggg atcatctata
     2221 ccgttgacga aggcgatgac tggaccgacc cgcaggtgct ggaaaaagcc aatccaaata
     2281 ttggcgtgtc ggtttatcgc gaatttttgt taagtcagca gcagcgtgcg aaaaataacg
     2341 cccgtctggc aaacgtcttt aaaacaaaac acctcaatat ctgggtgtcg gcgcgttcgg
     2401 cgtatttcaa cctggtgagc tggcagagct gcgaggataa atcactgacc cttgagcagt
     2461 tcgaggggca gccgtgcatt ctggcctttg acctggcgcg taagctggat atgaacagca
     2521 tggcgcgact ttatacccgc gagattgacg gtaaaacgca ttactacagt gtggccccgc
     2581 gtttctgggt accgtatgac acggtgtaca gcgtcgagaa aaatgaagat cgacggacag
     2641 ccgaacgctt tcagaaatgg gtggaaatgg gcgttctgac cgttaccgat ggtgcggaag
     2701 tggattatcg ctacatcctc gaggaggcca aagcggcgaa caaaatcagc ccggtcagtg
     2761 agtcacccat cgaccccttc ggggcgaccg ggttgtcaca tgaccttgct gatgaagacc
     2821 tgaatcccgt cactatcgtc cagaacttca ccaatatgtc cgacccgatg aaagagctgg
     2881 aagcggcgat tgaatcggga cgttttcatc atgacggcaa tcccatcatg acctggtgta
     2941 tcggcaacgt ggtcggcaaa accattccgg gtaacgatga tgtggtgaag cccgtcaaag
     3001 agcaggcgga aaacaaaatc gatggtgcag ttgcgctgat tatggcggtt ggcagagcca
     3061 tgctgtacga gaaagaagac acgctgtctg accacattga gtcctatggg atccgctcgc
     3121 tttaactgag gtaattatga tcatgctgat tctcgcgcct ctggtgggcg tgctgggggc
     3181 gcttttgctg gcgtatggtg cctggctgat ttatcccccg gcggggtttg ttgttgccgg
     3241 ggcgttgtgc ctgttctggt cgtggctggt ggcgcgatat ctcgaccgta cacagtcgtc
     3301 tgccggcgga ggtaaatagt gttcttttcg ggattatttc aacgaaaaag tgacgcaccg
     3361 gtgaccacgc cagcagagct ggcggatgct atcgggttgt cctacgacac ctataccgga
     3421 aagcagatca gcagccagcg ggccatgcga ctgacggcgg ttttttcctg tgtcagggtg
     3481 ctggcggagt cggtcgggat gttgccctgc aacctgtatc acctgaacgg cagcctgaag
     3541 cagagagcca ctggcgaacg tctgcataag ctgatctcca cgcatcccaa tggctatatg
     3601 acgccgcagg agttctggga gctggtggtc acctgtctgt gcctgcgggg aaacttttac
     3661 gcctacaaag tgaaagcatt tggcgaagtg gctgaactgc tgcccgtcga tcccggctgt
     3721 gtggtaccga agcttaacag tagctgggag ccggtctatc aggtcacatt cccggatggc
     3781 tccacggatg tactgagcca ggaggatatc tggcatgtgc gcacgctgac gctggacgga
     3841 ctggtggggc tgaatcccat cgcctatgcc cgcgaggcaa tatcgctggc ggcagcgacc
     3901 gaagagcacg gggccagact gttcagcaat ggcgcggtga cgtcgggtgt gttgcgtaca
     3961 gagcagacgc tgtcagatca ggcttatgag cgcctgaaga aagattttga ggagcgtcac
     4021 accgggcttg gcaatgctca ccgcccgatg atccttgaga tggggctgga ctggaagtcg
     4081 atggcgctga acgccgagga cagccagttc ctggaaaccc gcaggtttca gcttgaagaa
     4141 atctgtcgtc tgttccgggt gccgttgcac atggtgcaga acaccgatcg cgccaccttc
     4201 aacaatatcg aagagctggg gctgggattt atcaactatt cactggtgcc gtatctgacc
     4261 cgcatcgaac agcggatcaa caccggactg gtacgaaaaa gtaagcaggg cgtttattac
     4321 gccaaattta acgccggggc gttactgcgc ggggatatga agtcccgttt tgaagcctac
     4381 gccaccggga tcaactgggg aatttactct cccaatgact gccgcgacct ggaagatatg
     4441 aatccgcgtc ccggtggtga tgtctatctc acaccgatga acatgaccac gaaaccctcc
     4501 gatggcagta aagccggtaa gcagaaggat aatgccaatg cagacgaaac aacgtcttga
     4561 tgtaccgctg agtctgaaat ctgtcagtga ctccggtgag tttgaagggt atggctctgt
     4621 ctttggtgta aaggacagcc acgatgatgt ggtgatgtcc ggggcatttg ctgcttccct
     4681 gcgggcgtgg agtgacagaa aagcgttacc tgcactgctc tggcagcacc gtatggatga
     4741 gcccatcggt gtttacaccg aaatgaagga agacgatgtc gggctttacg tcagggggcg
     4801 gttgctcatt gatgatgatc ccctggcaaa acgcgcacat gcacacatga aggccggttc
     4861 gctaaccggc ctttctattg ggtacgtcct gaaggactgg gaatacgacc ggacgaaaga
     4921 agcctttctg ctgaaagaaa tcgacctctg ggaagtcagt ctggtgacgt ttccgtctaa
     4981 cgacgaggcg cggatcagcg acgtcaagaa cgcgctggcc cgcggggaaa tccccgaaca
     5041 gaaaaaaatc gaaagagtcc tgcgtgatgt cggactctcc cgtacccagg ccaaagcatt
     5101 catggccggg ggctatggcg cactgtccct gcgcgacgct gaggatgtgg gctctgcact
     5161 gaatgcactg aaaaatctga acttctaatc aggagaaata cgatggcggt tgatattaaa
     5221 gatgtcgaac aggtcgcgca ggagctgcag cagaagtttg acgacttcaa agcaaagaac
     5281 gacaagcgcg tggatgcgat tgagcaggaa aaaggcaagc ttgccgggca ggtggaaacc
     5341 ctgaacggga aactcagcga gctggaaaat ctcaaaagcg accttgaaaa agagctgctt
     5401 gagctgaaac gtccggcagg tggtgcgcaa aataaactgg ccaccgagca taaagaagcg
     5461 tttgtgggct tcctgcgtaa aggccgtgaa gacggtctgc gcgatctgga gcgtaaggca
     5521 ttgcaggtgg gcaccgatga agacggtggc tacgccgtgc cggaagcgct ggatcgcaac
     5581 attctcaacc tgctgaaaga tgaagtggtg atgcgtcagg aagccacggt gatcaccgtt
     5641 ggcggttccg actacaaaaa actggtgaat ctgggcggca cggcttccgg atgggtgggg
     5701 gaaacggata cgcgatccca gactgccacc tccagactgg agctgattga acctctcatg
     5761 ggggaaatct acggcaaccc gcaggctacc cagaaaatgc tggacgatgc cttcttcaac
     5821 gtggaagcat ggatcaacag cgagctggca accgaatttg ccgaacagga agaaattgcc
     5881 tttaccaccg gcgatggtac caagaagccg aaagggttcc tggcgtatga atccacggat
     5941 gaaaccgata aggtccgggc gttcggcaaa cttcagcata ttgtatccgg cgacgcgact
     6001 gcggtgaccg ctgatgccat tatcaaactg atttacacgc tgcgaaaggc acaccgcacc
     6061 ggcgcgaagt tcatgatgaa caacaacagc ctgtttgcca tccgtttgct gaaagacacc
     6121 gagggtaact atctgtggcg tccggggctg gaactggggc agccgtcctc tctggcgggt
     6181 tacggtatcg ctgaaaacga acagatgccg gatatcgccg ctgatgcgaa agccattgca
     6241 tttggtaact tcaaacgggg ttacaccatc gttgaccgta tcggcacccg cattctgcgt
     6301 gacccgtaca ccaataaacc gtttgtcggt ttttatacca ccaagcgcac cggcgggatg
     6361 ctggtcgatt cgcaggccat caaactgctg aagattgcag cggcgtaatc attcaggggc
     6421 gcggaaccgc gccccctgtt ctgacgggtg aagaatcatg atcctgaaac aagatctgaa
     6481 atggtcaccg gacggtatgc gtgttgaggt cattcgggcc ggtgagtatg acgacggggc
     6541 gctgcctgcc cgggtgcagg agattgcact tcaggccggg ttagcagagc gcggaaccag
     6601 tgcaaaaagc agtaaagcgg caaaagagaa aaaagccacg accagtaaag agggctgagt
     6661 atgcttctga caatagaaga gattaaagcc caactccggc tggatgagga tttcgatact
     6721 gatgaccgtc atctgcaact gctggcctgt gcggcgcaaa agcggacgga aacgtatctg
     6781 aaccggaagc tctatgcacc ggatgaaacc attccggaca gcgatccgga cggactacac
     6841 ctgccggatg atattcgtct ggggatgctg atgcttatca gccattttta cgaaaaccgc
     6901 tcgtcggtta cggaagtgga gaaactcgac atgccgcaga gttttggctg gcttgtcagc
     6961 ccgtacaggt actttccgca atgaaaattc gtcaggcgca gaccagcgca acctacatcc
     7021 tgccggaccc cggcgaactg aataaacgcg tcctgatccg ccagcgggtg gatatgcccg
     7081 cggataactt tggcgtggag cctcaatacc cggttgcgtt ccgggcatgg gcgaaggtta
     7141 tccagaccag tgccaccacc tggcaggaaa ccgcgcagac cggagacgcc atcacccatt
     7201 acatcaccat tcgctaccgc cgggggatca ctgctgatta tgaggtggtc tgtggtgaca
     7261 gtgtgtaccg cgtgaaacgt cagcgtgatc tgaacggagc gcggcgcttt ctgctgctgg
     7321 agtgtacgga gctgggcgaa tttacgcaga gtcacggagg caacaatggc gacttccttt
     7381 ttgcacgttg attttcagca gcccgcggag atgcgcttta accgcgcccg tgtccggcgg
     7441 gcgtttgtca cgattggtca gcgtcatatg cgtgatgccc gtcggctggt gatgcgccgt
     7501 gtgcggtcgg caccgggtga aaaccccggt tatcagaccg gacgcctggc tcgttcgatt
     7561 ggttacatgg tacccagagc cagtaaacat cgccctggtt ttatggcacg tatagcccct
     7621 aaccagcgta atggagaggg aaaccgccgt atcaccggtg atttttatcc ggcttttttg
     7681 ttctatggcg tgaggcgagg ggcaaagcgt cgtcgcagcc atcatcgtgg tgcatccggt
     7741 ggcagcggct ggcgactggc tccacgtaat aacttcatgg tggaaacgct tgaaaagaac
     7801 cgcagttgga cacgctattt tctggcgcgg gaattgcgta aatcactgaa gccggagcga
     7861 cgacacagat gaaactgacg cctgttattg ctgcactgcg tgcccgctgt ccgtattttg
     7921 aaaaccgggt tgcaggcgcg gcccagttca aaaatctgcc ggaggtcgga aagctgaaac
     7981 tcccggcggc atatgttgta ccgggtgatg attctccggg agaaaacaaa agccagaccg
     8041 actactggca ggagctgaaa gagggtttct ccgtggttgt catactgagt aacgggcgtg
     8101 atgagcgcgg tcagtttgcc tcgtatgatg tggtggacga tgtccggcag atgctcttta
     8161 aggctctgct gggctggaac ccggaggcgt gcggtaaccc gattacctat gacggcggca
     8221 cgctgctgga tctgaatcgt catgagctga tttatcagtt cgatttttcg gtcatcagcg
     8281 agctgactga agacgatacc cgccagcagg atgatctgaa cagtctggat gaactgcaaa
     8341 cgctggcgat tgatgttgat tatctcgatc ccggtaacgg gcctgacggc gatatcgaac
     8401 atcacaccga aataaccctt ccttcctgag aatcttcatg tttgtgaaac ctgttaaagg
     8461 gcggtcagtg cctgaccctg cccgcggtga ccttttgccc accgaagggc gaaatgttga
     8521 cgagaacaac tactggctgc gccgtgaagc agcgggtgat atccggcgcg tgaataaaaa
     8581 ggtgaacacc gatgacgata agctttaaca ccattccgtc gaatacgctg gttccgctgt
     8641 tttatgcgga aatggataac tcggcggcaa atactgtaca ggacagcggg gcatcgttgc
     8701 tgattggtca cgccaataac ggtgcagaga ttgttgccaa cagtctggtg ctgatgccgt
     8761 cggcagacta tgcacgccag atttgtggtg cgggaagtca gctggcgcgt atggtcgagg
     8821 cttatcgcca gaccgacccg tttggcgagc tgtatgtgat tgccgttccg gaagccacag
     8881 gcgcagcggc aacggttacg ctgacggtga ccggggcggc aaccgagacc ggcacggtga
     8941 atgtttatgt gggacgtacc cgcgtgcaga caccggtgac caacggcgat aacgtcacga
     9001 cgattgccag cagtatcaaa gatgccatca atgccgttcc ggccctgccg tttacggcct
     9061 catcttcggc aggcgtggtc acgctgaccg cgcgtcataa ggggctttgc gggaatgaaa
     9121 ttcctgtcag cctcaattac tacggctttg gtgggggcga agtgctgcca gcgggcgtac
     9181 agattgccgt ggcgacgggg accgccggaa cgggcgctcc ggttctcacc ggcgcggtgg
     9241 ctgcaatggc ggatgagccg tttgattata tctgcctgcc gttcaacgac acggcctccg
     9301 ttaacacgct ggtgaccgaa atgaacgata ccagcggtcg ctggagctat gcgcgtcagc
     9361 tgtatggcca tgtgtatacg gcaaagaccg gcacgctgtc agaactggtg accgcaggtg
     9421 accagtttaa ccagcagcac attaccctgg cggggtacga aaaagacacc cagacgcctg
     9481 ccgacgagct ggcggcaagc cgtaccgccc gcgcagcggt gtttatccgc aacgatccgg
     9541 cacgtcccac gcagaccggt gagctggtgg gaatgctgcc tgcgccgaag gggaaacggt
     9601 tcacgatgac cgaacaacag accctgctgt ctcatggcgt ggcaacggcg tatgtcgaaa
     9661 gcggggtgct gcgcattcag cgtgatgtca ccacgtacag gaaaaacgct tacggggttg
     9721 cggataacag ctacctcgac agcgagacgc tgcacaccag tgcgtatgta ctgcgcaaac
     9781 tgaaatccgt cattaccagt aagtacgggc gtcacaagct tgccagtgac ggtacccgct
     9841 ttggtcccgg tcaggcgatt gtcaccccgg cggtgattaa aggggaactg ctggcaacct
     9901 accgtcagct cgagcgtgcg gggatcgtgg aaaactacga actgttcaag cagtacctgg
     9961 ttgtggagcg tgatgccagc gatccgaacc gcctgaacac gctgttcccg cctgactatg
    10021 ttaaccagtt gcgtgtcttt gccgtggtta accagttccg tcttcagtat tcagaggagt
    10081 ctgcataatg gcccgtatcg ggggaacctg ttatttcaaa attgacggtc agcagctatc
    10141 gctgaccggc ggcattgagg tgcccatgaa caggacggtc aatgatgaca tcatcggcct
    10201 ggacggttca gtggaccgca aggaaactca ccgtgcgcct tatgtcaaag ggaccttcaa
    10261 ggtgccgaag aattttccgg tgagcaaaat cacctcgtct gatgagatga ccatcactgc
    10321 cgagctggcg aacggtcagg tctatgtact gtcgtctgcc tggctgcacg gcgaagcgaa
    10381 ccataatgcc gaagaaggca cggtcgatct tgagttccac ggtgaagaag gggattacca
    10441 gtaatgaaag agcttgagtt aaagaaaccg attaccgctc atggcgagac actctccgta
    10501 ctggagtttg atgagcccac cgggaaagat gtccgcgagc tggggtatcc ctaccagatg
    10561 aatcaggatg agtccgtcag acttctggcg catgtggtat cgaaatacat tgtgcggctg
    10621 gcgaaagtgc cgcaaagctc tgtcgaccag atgtctccgg cagacctgaa tgcagcggcg
    10681 tggcttgtgg ctggtttttt cctccaggcc tgacggctga atacctcact gatcgcttct
    10741 ttgactgcgc cagctactgg cgcattaatc ccttcgaatt gctgaatatg ccgatcagtg
    10801 aaattccctt gctggtcagt caggcaaaca ggatagagca ggagaaacgc acacatggct
    10861 gaatttgagc ttaaggcgtt gatcaccggt gtcgacaggc tttctcccgc gctgtcgaaa
    10921 atgcaaaaga aaatccgggg atttaaacgc caggcggaag aagcgtcaca gggtgggctg
    10981 gcgcttggtg gcggactggc agcgggtctg acgctttccc tgaaatctta tgccgatcag
    11041 gaaaacgccg ccaccgggct gaaagtcgcc atgatggatg cgaacggcga ggtcggaaag
    11101 agctttcagg acatcaataa actggctatt ggcctgggta accagctacc cggtacaacg
    11161 gctgattttc agaacatgat gcagatgctg gtgcgtcagg ggatcccggc agaaaacatt
    11221 cttggcggtg tgggtaaagc gacggcttat cttgcggtac aactgaaaaa aacaccggaa
    11281 gcggctgctg agtttgccgc aaagatgcag gatgctacag gaacggcgtc agaagacatg
    11341 atggggctgt tcgacactat ccagaaagcg ttttatctgg gcgttgacga taccaacatg
    11401 ttgtccttct tcactaaaac cagttctgtt ctgaagatgg tgaataagga cggtcttcag
    11461 gctgcacaga gccttgcccc tatcagcgtc atgatggatc agatggggat gaacggggag
    11521 tcggcaggta atgccctgcg aaaagttatc cagtccggat taagcgttaa gaaaatcagg
    11581 gacgtcaata aagtcatggc ccgccagaaa ctcggagtgc agctcgattt tactgacggc
    11641 aaagggagtt ttggcggtct tgataacatg tttaagcaac tggcaaagct gcgaaaactg
    11701 accgacgtta agcgaaccgg tgtacttaag gcaatatttg gtgatgatgc tgaaaccctt
    11761 caggtggtca atgctctgat cgataaagga aaggatggtt acgatcagat ccagcagaag
    11821 atgaataaac aggccagcct gaataaacgt gttcaggcac agcttggtac gctgtccaac
    11881 ctgtgggagg caatgacggg gaccgcaact aacggtcttg cagctattgg cggcgcattt
    11941 tctggtgacg ccaaaaatat cacgcaatgg ctgggggagt taggggaaaa attcacgaag
    12001 tttgcggatg aaaatcccag ggttattcgc ggcgtcgtcg ggcttgctgc cggtcttgcg
    12061 attctgaaac tgggattgat gggcgttggc ggtgccatca gtattgtcag caggattatg
    12121 tcgatgacgc cgattggcat gattgcgacg gcgatagccc tggctgcggg attaattatc
    12181 actaactggg atgttgtcgg accttatttt aagaaactct gggaaaccat tggtccttat
    12241 tttgaggctg gctgggaact tcttaagaag gtttttgcct ggtcgccgct ggggatagtg
    12301 atcaataact ggggaccggt tgttaagtgg tttcaggata tgtgggacaa gctgaagcca
    12361 attattgagt ggtttaccga cagttccggt gacacggtcg atgccattaa ctctgcgcag
    12421 tggggcgcgg gtgcttatga tgcttatggg acgggaatac cggcgcgggg atacacacct
    12481 tatccggcgg tagatccggc tcagtcaaac aacgcctccg atgccacagg cccgaatccc
    12541 ttcatgatta acaaagctat cgcgccaaaa gttgatggcg agatcaaggt ttcatttatg
    12601 aatatgccac caggtatgcg ggttacggaa acacgttcca gtggcattga tattaatcac
    12661 gatgttgggt acaccagatt taggtaaaga cgaacaggga gggccgcccc tccctgaact
    12721 tactgtgcga acacgcaatt tcggcctgat ggggagccga caattctgga cattttttcg
    12781 caaataacag ttacttgttc tcctttttta agagcagcag ctgttgattt ttcagagtct
    12841 tgcatttcca ttcttgctgg catgaattca ttttcagttc tgaatttaat aattatagag
    12901 tcagtaaagt ccttatcaat ggattgtacg atacctctaa cggcgattaa tttacctttt
    12961 aactgttcat cggtagcgac ttcattttct tcatactgtt taaacagctg tcgagcagta
    13021 gtgttgtaga tttctttttg cggtgccgca gcttccgtat cggatgagta tgaagaatta
    13081 gagcctttat cgttattgcc tgcaaaatat ccaataatca ccaacccgat gaaaatatat
    13141 aa
//
LOCUS       DAPGUL010000126        13027 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.128, whole genome shotgun sequence.
ACCESSION   DAPGUL010000126 DAPGUL010000000
VERSION     DAPGUL010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13027
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.128"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            283..849
                     /gene="yqaB"
                     /locus_tag="RHX21_003854"
     CDS             283..849
                     /gene="yqaB"
                     /locus_tag="RHX21_003854"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1-phosphate/6-phosphogluconate
                     phosphatase"
                     /protein_id="HDV1988978.1"
                     /translation="MYERYAGLIFDMDGTILDTEPTHRKAWREVLGHYGLQYDVQAMI
                     ALNGSPTWRIAQAIIELNQADLDPHALAREKTEAVRSMLLDSVEPLPLVEVVKSWHGR
                     RPMAVGTGSESAIAEALLAHLGLRRYFDAVVAADHVKHHKPAPDTFLLCAQRMGVQPT
                     QCVVFEDADFGIQAARAAGMDAVDVRLL"
     gene            846..1274
                     /locus_tag="RHX21_003855"
     CDS             846..1274
                     /locus_tag="RHX21_003855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDV1988979.1"
                     /translation="MSEALSLFSLFASSFLSATLLPGNSEVVLVAMLLSGISYPWVLV
                     LTATMGNSLGGLTNVILGRFFPLRKTSRWQEKATGWLKRYGAVTLLLSWMPVVGDLLC
                     LLAGWMRISWGPVIFFLCLGKALRYVAVAAATVQGMMWWH"
     gene            1347..2903
                     /gene="gshA"
                     /locus_tag="RHX21_003856"
     CDS             1347..2903
                     /gene="gshA"
                     /locus_tag="RHX21_003856"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HDV1988980.1"
                     /translation="MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGH
                     PEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPL
                     SMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFW
                     QAKCGDISGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPF
                     EKTECGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAK
                     IGIEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDI
                     NPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLG
                     IGCETAQFPLLQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSAR
                     ILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMETADTE
                     PFAVWLEKHA"
     gene            3053..3568
                     /gene="luxS"
                     /locus_tag="RHX21_003857"
     CDS             3053..3568
                     /gene="luxS"
                     /locus_tag="RHX21_003857"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008458247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HDV1988981.1"
                     /translation="MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPN
                     KEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVAD
                     AWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELA
                     LPKEKLQELHI"
     gene            complement(3632..5170)
                     /gene="emrB"
                     /locus_tag="RHX21_003858"
     CDS             complement(3632..5170)
                     /gene="emrB"
                     /locus_tag="RHX21_003858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter permease
                     subunit EmrB"
                     /protein_id="HDV1988982.1"
                     /translation="MQQQKPLEGAQLVIMTIALSLATFMQVLDSTIANVAIPTIAGNL
                     GSSLSQGTWVITSFGVANAISIPLTGWLAKRVGEVKLFLWSTIAFAIASWACGVSSSL
                     NMLIFFRVIQGIVAGPLIPLSQSLLLNNYPPAKRSIALALWSMTVIVAPICGPILGGY
                     ISDNYHWGWIFFINVPIGVAVVLMTLQTLRGRETRTERRRIDAVGLALLVIGIGSLQI
                     MLDRGKELDWFSSQEIIILTVVAVVAICFLIVWELTDDNPIVDLSLFKSRNFTIGCLC
                     ISLAYMLYFGAIVLLPQLLQEVYGYTATWAGLASAPVGIIPVILSPIIGRFAHKLDMR
                     RLVTFSFIMYAVCFYWRAYTFEPGMDFGASAWPQFIQGFAVACFFMPLTTITLSGLPP
                     ERLAAASSLSNFTRTLAGSIGTSITTTMWTNRESMHHAQLTESVNPFNPNAQAMYSQL
                     EGLGMTQQQASGWIAQQITNQGLIISANEIFWMSAGIFLVLLGLVWFAKPPFGAGGGG
                     GGAH"
     gene            complement(5187..6359)
                     /gene="emrA"
                     /locus_tag="RHX21_003859"
     CDS             complement(5187..6359)
                     /gene="emrA"
                     /locus_tag="RHX21_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter periplasmic
                     adaptor subunit EmrA"
                     /protein_id="HDV1988983.1"
                     /translation="MSANAETQTPQQPVKKSGKRKRLLLLLTLLFIIIAVAIGIYWFL
                     VLRHFEETDDAYVAGNQIQIMSQVSGSVTKVWADNTDFVKEGDVLVTLDPTDARQAFE
                     KAKTALASSVRQTHQLMINSKQLQANIEVQKIALAKAQSDYNRRVPLGNANLIGREEL
                     QHARDAVTSAQAQLDVAIQQYNANQAMILGTKLEDQPAVQQAATEVRNAWLALERTRI
                     VSPMTGYVSRRAVQPGAQISPTTPLMAVVPATNMWVDANFKETQIANMRIGQPVTITT
                     DIYGDDVKYTGKVVGLDMGTGSAFSLLPAQNATGNWIKVVQRLPVRIELDQKQLEQYP
                     LRIGLSTLVSVNTTNRDGQVLANKVRSTPVAVSTAREISLAPVNKLIDDIVKANAG"
     gene            complement(6486..7016)
                     /gene="emrR"
                     /locus_tag="RHX21_003860"
     CDS             complement(6486..7016)
                     /gene="emrR"
                     /locus_tag="RHX21_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter EmrAB
                     transcriptional repressor EmrR"
                     /protein_id="HDV1988984.1"
                     /translation="MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQSKLLENR
                     NKMLKAQGINETLFMALITLESQENHSIQPSELSCALGSSRTNATRIADELEKRGWIE
                     RRESDNDRRCLHLQLTEKGHEFLREVLPPQHNCLHQLWSALSTTEKDQLEQITRKLLS
                     RLDQMEQDGVVLEAMS"
     gene            complement(7107..7442)
                     /gene="ygaH"
                     /locus_tag="RHX21_003861"
     CDS             complement(7107..7442)
                     /gene="ygaH"
                     /locus_tag="RHX21_003861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-valine transporter subunit YgaH"
                     /protein_id="HDV1988985.1"
                     /translation="MSYEVLLLGLLVGVANYCFRYLPLRLRVGNARPTKRGAVGILLD
                     TIGIASICALLVVSTAPEVMHDTRRFVPTLVGFAVLGASFYKTRSIIIPTLLSALAYG
                     LAWKVMAII"
     gene            complement(7432..8169)
                     /gene="ygaZ"
                     /locus_tag="RHX21_003862"
     CDS             complement(7432..8169)
                     /gene="ygaZ"
                     /locus_tag="RHX21_003862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-valine exporter subunit YgaZ"
                     /protein_id="HDV1988986.1"
                     /translation="MESPTPQPAPGSATFMEGCKDSLPIVISYIPVAFAFGLNATRLG
                     FSPLESVFFSCIIYAGASQFVITAMLAAGSSLWVAALTVMAMDVRHVLYGPSLRSRII
                     QRLQKSKTALWAFGLTDEVFAAATAKLVRNNRRWSENWMIGIAFSSWSSWVFGTVIGA
                     FSGSGLLQGYPAVEAALGFMLPALFMSFLLASFQRKQSLCVTAALVGALAGVTLFSIP
                     VAILAGIVCGCLTALIQAFWQGAPDEL"
     gene            complement(8293..9477)
                     /locus_tag="RHX21_003863"
     CDS             complement(8293..9477)
                     /locus_tag="RHX21_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1988987.1"
                     /translation="MTKPNHELSPALIVLMSIATGLAVASNYYAQPLLDTIARNFSLS
                     ASSAGFIVTAAQLGYAAGLLFLVPLGDMFERRRLIVSMTLLAAGGMLITASSQSLAMM
                     ILGTALTGLFSVVAQILVPLAATLASPDKRGKVVGTIMSGLLLGILLARTVAGLLANL
                     GGWRTVFWVASVLMALMALALWRGLPQMKSETHLNYPQLLGSVFSMFISDKILRTRAL
                     LGCLTFANFSILWTSMAFLLAAPPFNYSDGVIGLFGLAGAAGALGARPAGGFADKGKS
                     HHTTTFGLLLLLLSWLAIWFGHTSVLALIIGILVLDLTVQGVHITNQTVIYRIHPDAR
                     NRLTAGYMTSYFIGGAAGSLISASAWQHGGWAGVCLAGATIALVNLLVWWRGFHRQEA
                     AN"
     gene            complement(9768..10760)
                     /gene="proX"
                     /locus_tag="RHX21_003864"
     CDS             complement(9768..10760)
                     /gene="proX"
                     /locus_tag="RHX21_003864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708493.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     substrate-binding protein ProX"
                     /protein_id="HDV1988988.1"
                     /translation="MRHSVLFATAFATLISTQTFAADLPGKGITVNPVQSTITEETFQ
                     TLLVSRALEKLGYTVNKPSEVDYNVGYTSLASGDATFTAVNWTPLHDNMYEAAGGDKK
                     FYREGVFVNGAAQGYLIDKKTADQYKITNIAQLKDPKIAKLFDTNGDGKADLTGCNPG
                     WGCEGAINHQLAAYELTNTVTHNQGNYAAMMADTISRYKEGKPVFYYTWTPYWVSNEL
                     KPGKDVVWLQVPFSALPGDKNADTKLPNGANYGFPVSTMHIVANKAWTEKNPAAAKLF
                     AIMQLPVADINAQNAIMHDGKASEGDIQGHVDGWIKAHQQQFDGWVNEALAAQK"
     gene            complement(10817..11881)
                     /gene="proW"
                     /locus_tag="RHX21_003865"
     CDS             complement(10817..11881)
                     /gene="proW"
                     /locus_tag="RHX21_003865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     permease ProW"
                     /protein_id="HDV1988989.1"
                     /translation="MADQNNPWDTTPAADSAAQSADAWGTPATAPTDGGGADWLTSTP
                     APNVEHFNILDPFHKTLIPLDSWVTEGIDWVVTHFRPVFQGVRVPVDYILNGFQQLLL
                     GMPAPVAIIVFALIAWQISGVGMGVATLVSLIAIGAIGAWSQAMVTLALVLTALLFCI
                     VIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFA
                     LPPIIRLTILGINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLAL
                     SMVVIASMIAVGGLGQMVLRGIGRLDMGLATVGGVGIVILAIILDRLTQAVGRDSRSR
                     GNRRWYTTGPVGLLTRPFIK"
     gene            complement(11874..>13027)
                     /gene="proV"
                     /locus_tag="RHX21_003866"
     CDS             complement(11874..>13027)
                     /gene="proV"
                     /locus_tag="RHX21_003866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein ProV"
                     /protein_id="HDV1988990.1"
                     /translation="PQRAFKYIEQGLSKEQILEKTGLSLGVKDASLAIEEGEIFVIMG
                     LSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREVRRKKIAMVFQSFALMP
                     HMTVLDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLAR
                     ALAINPDILLMDEAFSALDPLIRTEMQDELVKLQAKHQRTIVFISHDLDEAMRIGDRI
                     AIMQNGEVVQVGTPDEILNNPANDYVRTFFRGVDISQVFSAKDIARRTPNGLIRKTPG
                     FGPRSALKLLQDEDREYGYVIERGNKFVGAVSIDSLKTALTQQQGLDAALIDAPLAVD
                     AQTPLSELLSHVGQAPCAVPVVDEDQQYVGIISKGMLLRALDREGVNNG"
BASE COUNT         3229 a         3357 c         3451 g         2990 t
ORIGIN      
        1 catattctcc gtaaccttca gcaatgaagg tatcgaagag atagcggtat taaccgcagg
       61 caccagggag gataacgttg cgtcagcaac ggcccgaagg gcgaacgcca gtgagtaatc
      121 ctcccggatg caccatcttc tcccaaaaat ttccttcaaa aatatctcat ttctaaataa
      181 ctactttatc catttcctga attttcttct ccttcgccat cagcgacaaa atcaagcaat
      241 tacgctaaag tagcgtcata tttttcgact tgcgagaaga ccatgtacga gcgttatgca
      301 ggtttaattt ttgatatgga tggcacaatc ctggatacgg agcctacgca ccgtaaagcg
      361 tggcgcgaag tattagggca ctacggtctt cagtacgatg ttcaggcaat gattgcgctt
      421 aatggatcgc ccacctggcg tattgctcag gcaattattg agctgaatca ggccgatctc
      481 gacccgcatg cgttagcgcg tgaaaaaaca gaagcagtaa gaagtatgct gctggatagt
      541 gtcgagccgc ttcctcttgt tgaagtggtg aaaagttggc atggtcgtcg cccaatggct
      601 gtaggaacgg ggagtgaaag cgccatcgct gaggcattgc tggcgcacct gggattacgc
      661 cgttattttg acgccgtcgt cgctgctgat cacgtcaaac accataaacc cgcgccagac
      721 acatttttgt tgtgcgcgca gcgtatgggc gtgcaaccga cgcagtgtgt ggtctttgaa
      781 gatgccgatt tcggtattca ggcggcccgt gcagcaggca tggacgccgt ggatgttcgc
      841 ttgctgtgag tgaagcgtta tcgcttttct cgttgtttgc cagtagtttt ctcagcgcta
      901 cactattacc cggcaactcc gaagtcgtgc tggtggcaat gttgctttcc gggatcagtt
      961 atccctgggt tttagtttta acagcaacaa tgggtaatag ccttggaggg ttaactaacg
     1021 ttatccttgg gcgtttcttt ccattgcgta aaacatcgcg ctggcaagag aaagctaccg
     1081 gctggctgaa acgctatggt gcagtcacgc tattattaag ctggatgccc gtggttggcg
     1141 atttactgtg tctgttagcg ggatggatgc gcatctcctg gggaccggta atcttttttt
     1201 tgtgccttgg taaagcgtta cgctatgttg cagttgcagc agcgaccgtt cagggcatga
     1261 tgtggtggca ctaattgtag gcctgcacat atggtcacca ttacagttat gctaattaaa
     1321 acgattttga caggcgggag gtcaatttga tcccggacgt atcacaggcg ctggcctggc
     1381 tggaaaaaca tcctcaggcg ttaaagggga tacagcgtgg gctggagcgc gaaactttgc
     1441 gtgttaatgc tgatggcaca ctggcaacaa caggtcatcc tgaagcatta ggttccgcac
     1501 tgacgcacaa atggattact accgattttg cggaagcatt gctggaattc attacaccag
     1561 tggatggtga tattgaacat atgctgacct ttatgcgcga tctgcatcgt tatacggcgc
     1621 gcaatatggg tgatgagcgg atgtggccgt taagtatgcc atgctacatc gcagaaggtc
     1681 aggacatcga actggcacag tacggcactt ctaacaccgg acgctttaaa acgctgtatc
     1741 gtgaagggct gaaaaatcgc tacggcgcgc tgatgcaaac catttccggc gtgcactaca
     1801 atttctcttt gccaatggca ttctggcaag cgaagtgcgg tgatatctcg ggcgctgatg
     1861 ccaaagagaa aatttctgcg ggctatttcc gcgttatccg caattactat cgtttcggtt
     1921 gggtcattcc ttatctgttt ggtgcatctc cggcgatttg ttcttctttc ctgcaaggaa
     1981 aaccaacgtc gctgccgttt gagaaaaccg agtgcggtat gtattacctg ccgtatgcga
     2041 cctctcttcg tttgagcgat ctcggctata ccaataaatc gcaaagcaat cttggtatta
     2101 ccttcaacga tctttacgag tacgtagcgg gccttaaaca ggcaatcaaa acgccatcgg
     2161 aagagtacgc gaagattggt attgagaaag acggtaagag gctgcaaatc aatagcaacg
     2221 tgctgcagat tgaaaacgaa ctgtatgcgc cgattcgtcc aaaacgcgtt acccgcagcg
     2281 gcgagtcacc ttctgatgcg ctgttacgtg gcggcattga atatattgaa gtgcgttcgc
     2341 tggacatcaa cccgttctcg ccgattggtg tagatgaaca gcaggtgcga ttcctcgacc
     2401 tgtttatggt ctggtgtgcg ctggctgatg caccggaaat gagcagtagc gaacttgcct
     2461 gtacgcgcgt taactggaac cgggtgatcc ttgaaggtcg caaaccgggc ctgacgctgg
     2521 gtatcggctg cgaaaccgcg cagttcccgt tactgcaggt ggggaaagat ctgttccgcg
     2581 atctgaaacg cgtcgcgcaa acgctggata gcattaacgg cggcgaagcg tatcagaaag
     2641 tgtgtgatga actggttgcc tgcttcgata atcccgatct gactttctct gcccgtatct
     2701 taaggtctat gattgatact ggtattggcg gaacaggcaa agcgtttgca gaagcctacc
     2761 gtaatctgct gcgtgaagag ccgctggaaa ttctgcgcga agaggatttt gtagccgagc
     2821 gcgaggcatc tgaacgccgt cagcaggaaa tggaaaccgc tgataccgaa ccgtttgcgg
     2881 tgtggctgga aaaacacgcc tgacagaaaa gaaaaaggcc actcgtgagt ggccaaaatt
     2941 tcatctctga attcagggat gatgataaca aatgcgcgtc tttcatatac tcagactcgc
     3001 ctgggaagaa agagttcaga aaattttaaa aaaaattacc ggaggtggct aaatgccgtt
     3061 gttagatagc ttcacagtcg atcatacccg gatggaagcg cctgcagttc gggtggcgaa
     3121 aacaatgaac accccgcatg gcgacgcaat caccgtgttc gatctgcgct tctgcgtgcc
     3181 gaacaaagaa gtgatgccag aaagagggat ccataccctg gagcacctgt ttgctggttt
     3241 tatgcgtaac catcttaacg gtaatggtgt agagattatc gatatctcgc caatgggctg
     3301 ccgcaccggt ttttatatga gtctgattgg tacgccagat gagcagcgtg ttgctgatgc
     3361 ctggaaagcg gcaatggaag acgtgctgaa agtgcaggat cagaatcaga tcccggaact
     3421 gaacgtctac cagtgtggca cttaccagat gcactcgttg caggaagcgc aggatattgc
     3481 gcgtagcatt ctggaacgtg acgtacgcat caacagcaac gaagaactgg cactgccgaa
     3541 agagaagttg caggaactgc acatctagtc agtaaactat cttcacaatt aattgaaaaa
     3601 agccagttca aatgaactgg cttagttgta cttagtgcgc accgcctccg ccgccacctg
     3661 cgccaaatgg cggtttagca aaccacacca gccccagcag tacgaggaat atcccggctg
     3721 acatccagaa gatctcattg gcggaaataa tcagcccctg attggtgatc tgctgggcaa
     3781 tccagcctga tgcctgctgt tgcgtcatcc caagcccttc cagttgactg tacatcgcct
     3841 gggcattcgg gttgaacggg tttaccgact cagtcaactg cgcatggtgc atcgactcgc
     3901 ggttggtcca catggtcgtg gttatcgacg tgccgataga ccccgccagc gttcgcgtaa
     3961 agttagagag gctcgatgcc gccgccagtc gttccggtgg caaaccagac agcgtaatgg
     4021 tggtcagcgg cataaagaag caggccaccg caaacccctg gataaactgc ggccaggccg
     4081 acgcgccaaa atccatacct ggttcaaagg tataggcacg ccagtagaag cagacggcat
     4141 acataataaa gctgaaggtt accagccgcc gcatatccag tttatgcgcg aagcggccga
     4201 taatcggcga caggatcacc ggaataatcc ctaccggcgc agaggccaaa cctgcccagg
     4261 tcgccgtgta accgtagacc tcctgcaaca actgcggcag cagaacaata gcgccgaagt
     4321 agagcatata cgcgaggctg atacacaagc agccgatggt gaagttgcgc gacttaaaca
     4381 acgacagatc gactatcggg ttatcgtcgg tcagctccca gacaatcagg aagcagatag
     4441 ccaccaccgc caccacggta agaatgataa tttcctgtga tgaaaaccag tccagctctt
     4501 taccgcggtc gagcataatc tgcaggctgc cgataccaat aaccagcagt gccagcccca
     4561 cggcatcaat ccgccgccgt tcggtgcggg tttcacgtcc gcgcagagtt tgcagtgtca
     4621 tcaacaccac cgccacgcca atcggcacgt tgatgaagaa tatccagccc cagtggtaat
     4681 tatcgctgat ataaccgccg aggatcgggc cgcaaattgg cgcgacaatc accgtcatcg
     4741 accacaacgc cagcgcgatc gagcgtttgg ctggcgggta gttattcagc aatagacttt
     4801 gcgaaagcgg gatcaacggc ccggcgacaa tcccctgaat cacgcggaag aagatcagca
     4861 tattcaggct gctggagaca ccacacgccc acgacgcaat agcaaaggcg atggtggacc
     4921 aaaggaacag tttcacttcc ccgacgcgct ttgccagcca gccggtaagc gggatcgaga
     4981 tggcattcgc caccccgaaa gaagtgatta cccacgttcc ctggctgagc gatgagccca
     5041 gattcccggc gatagtgggg atcgccacgt tagcaatggt ggagtccagc acctgcatga
     5101 atgtcgccag tgacagcgca atcgtcataa tgaccagttg cgcgccttcc agcggttttt
     5161 gctgttgcat cacacgcacc tctggattag ccagcgttag cttttacgat atcgtcgatc
     5221 agtttattga caggtgccag gctgatttca cgcgcggtac ttaccgcgac cggtgttgaa
     5281 cgtactttat ttgccagtac ctgaccgtca cggttagtgg tattgacgct caccagcgtg
     5341 gacaaaccaa tgcgcagcgg gtattgctcc agctgtttct ggtccagttc gatacgcaca
     5401 ggtagacgct gaacgacttt gatccagtta ccggtcgcat tttgcgccgg aagcagtgag
     5461 aatgcgctac ctgtgcccat atccagacca accactttac cggtgtattt cacatcatcg
     5521 ccgtaaatat ccgtggtgat agtgaccggc tgaccgatac gcatattggc aatctgcgtc
     5581 tctttaaagt tggcatccac ccacatattg gtggctggaa cgaccgccat cagcggcgtc
     5641 gttgggctaa tttgcgcccc aggctgtacc gcgcggcggg agacataacc ggtcatcgga
     5701 ctgacaatac gggtacgctc cagcgccagc caggcgttac gtacttcggt ggcagcctgt
     5761 tgcacggcag gctgatcttc cagtttagtc cccagaatca tcgcctgatt ggcattgtat
     5821 tgttgaatag cgacgtccag ttgcgcctgg gcactggtga cggcgtcgcg ggcgtgttgc
     5881 agctcttcgc gaccaatcag gttggcattg cccagcggca cacggcggtt gtagtcgctt
     5941 tgtgctttcg cgagggcgat tttttgcacc tcaatattcg cctgcaactg tttgctgtta
     6001 atcatcagct ggtgggtttg gcgaacgctg gaagccagtg cagttttggc tttttcaaac
     6061 gcctggcgag catctgtcgg gtcgagagtg accagaacat cgccttcttt tacaaaatcg
     6121 gtgttatcgg cccagacttt cgtcacgctg ccagacacct gagacataat ttgaatctga
     6181 ttccctgcca cgtatgcgtc atcggtttct tcgaaatgac gcagtaccaa aaaccaataa
     6241 atccctatcg ctacggcaat aattataaag agcaaggtga gaaggaggag cagacgctta
     6301 cgtttgccgc tcttctttac cggttgctgc ggggtttgag tctccgcatt tgcgctcata
     6361 ttgttctcca cgatcttctt aactcatcgg ctgagccgac ctgcttgcca aaaaggccag
     6421 catgttgcga tgctggccgg tcattttttc ttttataaat ctggattttt gagcgagatg
     6481 acgcgttagc tcatcgcttc gagaaccaca ccgtcttgtt ccatctggtc gagacgggag
     6541 agcaatttgc gggtgatttg ctcgagctga tctttttctg ttgtgctgag cgcggaccag
     6601 agttgatgca ggcagttatg ctgcggtggt aaaacctcgc gcaaaaactc gtgacctttt
     6661 tccgttaatt gcagatgcag gcagcggcga tcgttatcgc tttcacgacg ttcgatccaa
     6721 ccgcgttttt ccagttcatc ggcaatacgc gtcgcgttgg tacgggatga tccaagagca
     6781 caacttaatt cagaaggctg aatactgtgg ttttcctgag actccagcgt aatcaacgcc
     6841 ataaacaacg tctcgttaat cccctgagcc ttcagcattt tattgcggtt ctccagcagc
     6901 ttgctttgca tgtgcatgca aagacgagtc agaaggatct cctgataagg aaaatcttcg
     6961 tggcggctgg cgcgaaattt tagcatttgt tcaatgggcg taaacgaact atccatttgg
     7021 gtatgacctc attaatttca gccgatatag taacgacagt gacaaataaa gtaaatgtat
     7081 tgttttagaa aaatgattct tgtgggttat ataatcgcca tcactttcca ggcgagccca
     7141 taggccagcg cactaagcag tgttgggatg ataatgctgc gtgttttata gaaactggca
     7201 cccagtaccg cgaagccgac cagcgtgggc acgaaacggc gtgtatcgtg catcacttct
     7261 ggtgcggtag agacaaccag cagagcgcat atcgaggcga tgccaatggt gtcgagcaaa
     7321 atacctaccg cgccacgttt ggttgggcgg gcattaccca cacgcaggcg cagcggcaaa
     7381 tagcggaagc aataattcgc cacgccaacc agtaacccaa gcagcagaac ctcatagctc
     7441 atcgggcgct ccttgccaga atgcctggat taacgcagtg aggcagccac agacaatgcc
     7501 tgccagaatg gcgacgggaa tagaaaatag cgttacgcct gcaagggcac caactaacgc
     7561 tgcggtaacg caaagagatt gtttgcgctg gaaagaggcg agcaggaaac tcataaagag
     7621 tgccggaagc ataaaaccta atgcagcttc aacggcggga taaccttgca gcaagccgct
     7681 gccggagaat gcccctatta ccgtaccaaa tacccacgat gaccatgaac tgaaggcaat
     7741 gccgatcatc cagttctcgc tccagcggcg attattgcgt accagttttg cggttgcggc
     7801 ggcaaaaacc tcatccgtca ggccaaatgc ccacagggcg gttttcgatt tttgcagacg
     7861 ctgaataata cggctacgca gtgacgggcc atacaacaca tggcgaacat ccattgccat
     7921 gacggtcagt gcagcaaccc acaaactact cccggctgcc agcatcgcgg taatgacgaa
     7981 ctggctcgcg cctgcataaa tgatgcagga gaaaaaaacg ctttcgagag gagagaatcc
     8041 cagacgggtc gcattcagac cgaacgcaaa ggccaccgga atataactaa taacaatcgg
     8101 taaactgtct ttgcatcctt ccatgaaggt cgccgaacca ggagcaggct gtggagtagg
     8161 gctttccata gagtgtacgc ttaacgattg ttaatattat aaatagactg aatgaatatc
     8221 ttaaccttat cagactgatg ggcttcttaa cacccttata agtgtaaagc cacgaaaacg
     8281 gttgctgatt gcttaatttg cggcttcctg acgatgaaaa cctcgccacc agaccagtaa
     8341 gttaaccagg gcaatcgtcg cgccagccag acaaacgcca gcccaaccgc catgttgcca
     8401 ggctgaggct gaaattagcg aaccggcggc accgccaata aagtagctgg tcatgtaacc
     8461 tgcggtcagg cgattacgcg catcagggtg tattcgataa attaccgtct ggttagtgat
     8521 atgcacgccc tgtacggtga gatccagcac caggatgccg ataatcagcg ccagtacgga
     8581 agtgtgacca aaccagatcg ccagccatga aagtaatagc agcagcagac cgaaagttgt
     8641 ggtgtggtgc gatttaccct tatcggcaaa accgcccgcc ggacgagcgc ccaacgctcc
     8701 ggcagctccc gcaagtccaa acagaccaat gacaccatcg ctgtagttaa aaggtggagc
     8761 ggcaagcaaa aaggccattg aggtccagag aatgctgaag ttggcaaagg tcaggcagcc
     8821 cagcaatgcg cgggtgcgca ggatcttatc gctgataaac atgctgaaaa cggaacctaa
     8881 caactgtggg tagttgaggt gggtttctga tttcatttgt ggcagaccac gccataatgc
     8941 cagcgccatc agtgccatta acaccgaggc aacccaaaag acggtgcgcc agccgccgag
     9001 attcgccagc aatccggcaa cggtccgtgc gagtaagatc cccaacagca gaccgctcat
     9061 aatagtgcca accactttgc cgcgtttgtc cggtgaagcc agcgtcgctg ccagcggaac
     9121 cagaatttgt gccacgactg agaataaacc ggttaatgcc gtaccgagga tcatcatcgc
     9181 cagtgactga ctgctggcag tgattaacat accgcccgct gccagtaagg tcatcgagac
     9241 aatcaggcgg cggcgttcaa acatatcacc gaggggaaca agaaacagta gacctgcggc
     9301 atagcccaac tgcgcggcgg taacaataaa gcctgccgaa ctggcggaaa gggaaaagtt
     9361 acgcgcgatg gtgtcgagca atggctgggc gtaatagtta ctggctaccg ccagaccggt
     9421 ggcgatagac atcagcacga tcagcgccgg gctaagctca tgattaggtt tagtcattat
     9481 ttttgttcat caggtgatga ttaagctgga aatcaataat agcggatgtt gatgaatatg
     9541 ggatgaaaga tagattgttg aaatgtgcga tgtggtttgt aggcatgata agacgcgcca
     9601 gcgtcgcatc aggcattgtg cacagaacgg cggatgcggc gaaaacgcct tatccgccat
     9661 acgaatgagt gtattttgta ggcatgataa gacgcgtcag cgtcgcatca ggcattgtgt
     9721 acagagcggc ggatgaggca aaaacgcctt atccgcctga ataaaaatta cttctgcgct
     9781 gccagcgcct cattcaccca gccatcgaac tgctgctggt gggctttgat ccagccatca
     9841 acgtggccct gaatatcgcc ttctgaggct ttgccgtcat gcataatggc gttctgggcg
     9901 ttaatatcgg ccactggcaa ctgcataatg gcaaacagtt tggctgccgc cggatttttc
     9961 tcggtccagg ctttgttggc aacgatatgc atggtgctga ccgggaagcc gtaattcgcg
    10021 ccattcggca gtttggtatc ggcattttta tcgcccggca gtgcggagaa cggcacctgc
    10081 aaccagacca catctttccc tggcttcagc tcattactca cccagtacgg cgtccaggtg
    10141 taataaaaca ccggtttgcc ctctttgtag cgactgatgg tgtcggccat catcgctgcg
    10201 tagttcccct gattatgcgt cacggtgttg gtcagttcat acgcggcaag ctggtggttg
    10261 atggcacctt cgcagcccca gccagggtta caaccggtta aatccgcttt accgtcgccg
    10321 ttggtatcga acagtttggc gatcttcgga tctttcagtt gtgcgatgtt ggtgatttta
    10381 tactggtcgg cggttttctt atcgatcagg taaccctgtg ccgcgccgtt aacaaatacc
    10441 ccttcacgat aaaatttctt atcgccaccg gcagcttcgt acatgttgtc atgcagcggc
    10501 gtccagttca cggcggtgaa ggttgcatcg ccggaagcaa gcgaggtgta gccaacgttg
    10561 taatctactt cgctgggttt attgacggta taacctaatt tctccagcgc acgactgacc
    10621 agcagtgtct ggaaggtttc ttcggtgatg gtgctttgaa ctggattaac tgtaatgcct
    10681 ttgcccggca ggtcggcagc aaaagtttgt gtagagataa gcgtggcaaa cgctgtcgca
    10741 aaaagtacgc tatgtcgcat tgttattcct ttttttggca gggtgatatg cccggcgtta
    10801 ccgggcaagt gcagagttac ttaatgaatg ggcgggtcag cagaccgaca gggccagtgg
    10861 tgtaccagcg acggttgccg cgactgcgtg agtcgcgccc aacggcctgc gtcaggcggt
    10921 cgaggataat ggcgaggatc acaatcccga cgccgccaac ggtggcaagc cccatatcca
    10981 gacgaccgat accgcgaagt accatctgac ccagcccgcc gacggcaatc atcgaggcaa
    11041 tgaccaccat agaaagggcc agcatcagcg tctggttaac gcccgccata atggtcggca
    11101 tcgccagcgg taactgaact ttgaacagca tctggcgcgg gctggcaccg aatgagcgcg
    11161 aggcttcaat cagatccgcc ggaacctggt taatccccag aatggtcaga cggataatcg
    11221 gcggcagagc aaagatgatc gtcaccacca cgcccggcac gttaccgata ccaaatagca
    11281 tgacgattgg caccagataa acaaacgctg gcgtggtctg catggcatca agcagtggac
    11341 gaataatttt cgccgctcgc ggacttctcg ccagccagat ccccaacggc aaaccgatga
    11401 cgatacagaa cagcagggcg gttaacacca gcgccagagt aaccattgcc tgcgaccagg
    11461 caccgattgc gccgatggca atcagcgaaa ccagcgtcgc cacgcccatt ccgaccccgg
    11521 aaatctgcca ggcgatgaga gcgaaaacga taatcgccac cggtgcgggc atacccagca
    11581 gcaactgctg gaaaccgttg aggatataat caaccggaac gcgcacgccc tggaagacgg
    11641 gacggaaatg ggtaacaacc cagtcgatcc cttcagtgac ccaactgtcg agcgggatca
    11701 gcgttttatg gaacggatcg agaatattaa aatgctcgac gtttggcgca ggcgtactgg
    11761 tcagccagtc agcaccaccg ccgtcagtcg gtgcagtcgc cggtgtaccc caggcgtctg
    11821 cggattgcgc ggcactgtcc gccgctggcg tggtatccca cggattattt tgatcagcca
    11881 ttatttaccc cctcacgatc taaagcgcgc agcagcattc ctttcgaaat gatgccgaca
    11941 tactgttggt cctcgtcgac cacgggcacc gcacagggtg cctgtccgac atgagagagc
    12001 aactcgctaa gaggcgtttg tgcatcgact gctaacggcg catcaatcag cgccgcatca
    12061 agaccttgct gctgcgttaa cgcggtttta agcgaatcga tggagactgc gccgacaaac
    12121 ttattaccgc gttcgataac gtagccatat tcgcgatctt catcctgcaa taatttcagt
    12181 gccgaacgtg ggccgaagcc aggggtttta cgaattaagc cattcggtgt ccggcgggca
    12241 atatctttcg cactgaatac ctgactaata tcaacgccac ggaagaaggt acggacataa
    12301 tcattcgccg gattattgag aatttcatcc ggtgtgccga cctgtaccac ttcaccattt
    12361 tgcataatgg caattcggtc gccaatacgc atagcctcat cgagatcgtg ggaaataaag
    12421 acaatggtgc gctgatgttt cgcctgtaat tttaccagct catcctgcat ctcggtgcga
    12481 attaatggat cgagcgccga gaaggcttcg tccattaata atatatccgg attaatcgct
    12541 aacgcgcggg ctaatcccac acgttgacgc atcccgccag agagttcatc cgggtagctg
    12601 tgggcataat tttccagccc gacctgacgc agtgcatcaa gggctttttc ccggcgttct
    12661 tcggcattaa ttccggccaa ttccataccg aacgcagtat tgtccagcac ggtcatatgc
    12721 ggcattaagg caaaggactg gaagaccatc gcaatctttt ttctgcgcac ctcacggagt
    12781 tcggcatcgg atattttggc aatatccaca ccatcaatca gcacttgccc gcgggtgggt
    12841 tcaatcaggc gattgagaag gcgtaccatt gtggatttac ccgagccgga taatcccatg
    12901 atgacaaata tctcgccttc ttcaatggcc agactggcgt cttttacgcc aagcgatagc
    12961 ccagtttttt ccagaatttg ttctttcgaa agtccttgtt cgatatattt gaacgctcgc
    13021 tgtggat
//
LOCUS       DAPGUL010000127        12989 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.129, whole genome shotgun sequence.
ACCESSION   DAPGUL010000127 DAPGUL010000000
VERSION     DAPGUL010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12989
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.129"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            24..341
                     /locus_tag="RHX21_003867"
     CDS             24..341
                     /locus_tag="RHX21_003867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001183281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HDV1988991.1"
                     /translation="MQPVFLFKKRTGAMGGHVAGTAGFCVAVPAFYSWSMSEVIDKDT
                     RSSERTDYPHYASEVALAFGSRVVGLELAKMIVDAWLGAQYEGGRHQQRVEAITAIEQ
                     RRN"
     gene            410..739
                     /gene="yjdP"
                     /locus_tag="RHX21_003868"
     CDS             410..739
                     /gene="yjdP"
                     /locus_tag="RHX21_003868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YjdP"
                     /protein_id="HDV1988992.1"
                     /translation="MKRFPLFLLFTLLTLSTVPAQADIIDDTIGNIQQAINDAYNPDR
                     GRDYEDSRDDGWQREVSDDRRRQYDDRRRQFEDRRRQLDDRQRQLDLERRQLEDEERR
                     MEDEYGR"
     gene            complement(886..1644)
                     /gene="phnP"
                     /locus_tag="RHX21_003869"
     CDS             complement(886..1644)
                     /gene="phnP"
                     /locus_tag="RHX21_003869"
                     /EC_number="3.1.4.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate metabolism protein PhnP"
                     /protein_id="HDV1988993.1"
                     /translation="MSLTLTLTGTGGAQGVPAWGCECAACARARRSPQYRRQPCSGVV
                     KFNDAITLIDAGRHDLTDRWSPGSFQQFLLTHYHMDHVQGLFPLRWGVGDVIPVYGPP
                     DEQGCDDLFKHPGLLDFSHTVEPFVVFDLQGLQVTPLPLNHSKLTFGYLLETAHSRVA
                     WLSDTAGLPEKTLKFLLNNHPQVMVIDCSHPPRADAPRNHCDLNTVLALNQVIRSPQV
                     ILTHISHQFDAWLMENALPSGFEVGFDGMEIGVA"
     gene            complement(1646..2080)
                     /gene="phnO"
                     /locus_tag="RHX21_003870"
     CDS             complement(1646..2080)
                     /gene="phnO"
                     /locus_tag="RHX21_003870"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoalkylphosphonate N-acetyltransferase"
                     /protein_id="HDV1988994.1"
                     /translation="MPACELRPATQYDTDAVYALICELKQAEFDHHAFRVGFNANLRD
                     PNMRYHLALLDGEVVGMIGLHLQFHLHHVNWIGEIQELVVMPQARGLNVGSKLLAWAE
                     EEARQAGAEMTELSTNVKRHDAHRFYLREGYEQSHFRFTKAL"
     gene            complement(2067..2624)
                     /gene="phnN"
                     /locus_tag="RHX21_003871"
     CDS             complement(2067..2624)
                     /gene="phnN"
                     /locus_tag="RHX21_003871"
                     /EC_number="2.7.4.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 1,5-bisphosphokinase"
                     /protein_id="HDV1988995.1"
                     /translation="MMGKLIWLMGPSGSGKDSLLAELRLREQTQLLVAHRYITRDASA
                     GSENHIALSEREFFTRAGQNLLALSWHANGLYYGVGIEIDLWLHAGFDVVVNGSRAHL
                     PQARARYQSALLPVCLQVSPEILRQRLENRGRENASEINARLARAARYTPQDCHTLNN
                     DGSLRQSVDTLLTLIHQKEKHHACL"
     gene            complement(2624..3760)
                     /gene="phnM"
                     /locus_tag="RHX21_003872"
     CDS             complement(2624..3760)
                     /gene="phnM"
                     /locus_tag="RHX21_003872"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HDV1988996.1"
                     /translation="MIINNVKLVLENEVVHGSLEVQDGEIRAFAESQSRLPEAMDGEG
                     GWLLPGLIELHTDNLDKFFTPRPKVDWPAHSAMSSHDALMVASGITTVLDAVAIGDVR
                     DGGDRLENLEKMINTIEETQKRGVNRAEHRLHLRCELPHHTTLPLFEKLVQREPVTLV
                     SLMDHSPGQRQFANREKYREYYQGKYSLTDAQMQQYEEEQLALAARWSQPNRESIAAL
                     CRARQIALASHDDATHAHVAESHQLGSVIAEFPTTFEAAEASRKHGMNVLMGAPNIVR
                     GGSHSGNVAASELAQLGLLDILSSDYYPASLLDAAFRVADDESNRFTLPQAVRLVTKN
                     PAQALNLQDRGVIGEGKRADLVLAHRQGNHIHIDHVWRQGKRVF"
     gene            complement(3757..4437)
                     /gene="phnL"
                     /locus_tag="RHX21_003873"
     CDS             complement(3757..4437)
                     /gene="phnL"
                     /locus_tag="RHX21_003873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnL"
                     /protein_id="HDV1988997.1"
                     /translation="MINVQNVSKTFILHQQNGVRLPVLNRASLTVNAGECVVLHGHSG
                     SGKSTLLRSLYANYLPDEGQIQIKHGDEWVDLVTAPARKVVEIRKTTVGWVSQFLRVI
                     PRISALEVVMQPLLDTGVPREACAAKAARLLTRLNVPERLWHLAPSTFSGGEQQRVNI
                     ARGFIVDYPILLLDEPTASLDAKNSAAVVELIREAKTRGAAIVGIFHDEAVRNDVADR
                     LHPMGASA"
     gene            complement(4548..5306)
                     /gene="phnK"
                     /locus_tag="RHX21_003874"
     CDS             complement(4548..5306)
                     /gene="phnK"
                     /locus_tag="RHX21_003874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnK"
                     /protein_id="HDV1988998.1"
                     /translation="MNQPLLSVNNLTHLYAPGKGFSDVSFDLWPGEVLGIVGESGSGK
                     TTLLKSISARLTPQQGEIHYESRSLYAMSEADRRRLLRTEWGVVHQHPLDGLRRQVSA
                     GGNIGERLMATGARHYGDIRATAQKWLEEVEIPANRIDDLPTTFSGGMQQRLQIARNL
                     VTHPKLVFMDEPTGGLDVSVQARLLDLLRGLVVELNLAVVIVTHDLGVARLLADRLLV
                     MKQGQVVESGLTDRVLDDPHHPYTQLLVSSVLQN"
     gene            complement(5303..6148)
                     /gene="phnJ"
                     /locus_tag="RHX21_003875"
     CDS             complement(5303..6148)
                     /gene="phnJ"
                     /locus_tag="RHX21_003875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HDV1988999.1"
                     /translation="MANLSGYNFAYLDEQTKRMIRRAILKAVAIPGYQVPFGGREMPM
                     PYGWGTGGIQLTASVIGESDVLKVIDQGADDTTNAVSIRNFFKRVTGVNTTERTDDAT
                     LIQTRHRIPETPLTEDQIIIFQVPIPEPLRFIEPRETETRTMHALEEYGVMQVKLYED
                     IARFGHIATTYAYPVKVNGRYVMDPSPIPKFDNPKMDMMPALQLFGAGREKRIYAVPP
                     FTRVESLDFDDHPFTVQQWDEPCAICGSTHSYLDEVVLDDAGNRMFVCSDTDYCRQQS
                     EAKSQ"
     gene            complement(6141..7205)
                     /gene="phnI"
                     /locus_tag="RHX21_003876"
     CDS             complement(6141..7205)
                     /gene="phnI"
                     /locus_tag="RHX21_003876"
                     /EC_number="2.7.8.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate synthase subunit PhnI"
                     /protein_id="HDV1989000.1"
                     /translation="MYVAVKGGEKAIDAAHALQESRRRGDTDLPELSVAQIEQQLNLA
                     VDRVMTEGGIADRELAALALKQASGDNVEAIFLLRAYRTTLAKLAVSEPLDTTEMRLE
                     RRISAVYKDIPGGQLLGPTYDYTHRLLDFTLLANGEAPTLTTADSEQQPSPHVFSLLA
                     RQGLVKFEEDSGAQPDDITRTPPVYPCSRSSRLQQLMRGDEGYLLALAYSTQRGYGRN
                     HPFAGEIRSGYIDVSIVPEELGFAVNVGELLMTECEMVNGFIDPPDEPPHFTRGYGLV
                     FGMSERKAMAMALVDRALQAPEYGEHATGPAQDEEFVLAHADNVEAAGFVSHLKLPHY
                     VDFQAELELLKRLQQEKNHG"
     gene            complement(7205..7789)
                     /gene="phnH"
                     /locus_tag="RHX21_003877"
     CDS             complement(7205..7789)
                     /gene="phnH"
                     /locus_tag="RHX21_003877"
                     /EC_number="2.7.8.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HDV1989001.1"
                     /translation="MTLETAFMLPVQDAQHSFRRLLKAMSEPGVIVALHQLKRGWQPL
                     NIATTSVLLTLADNDTPVWLAAPLSNDIVSQSLRFHTNAPLVSQPEQATFAVTDEAIS
                     SEQLNALSTGTAVAPEAGATLILQVASLSGGRMLRLTGAGIAEERMIAPQLPECILHE
                     LTERPHPFPLGIDLILTCGERLLAIPRTTHVEVC"
     gene            complement(7786..8238)
                     /gene="phnG"
                     /locus_tag="RHX21_003878"
     CDS             complement(7786..8238)
                     /gene="phnG"
                     /locus_tag="RHX21_003878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HDV1989002.1"
                     /translation="MHADTATRQHWMSVLAHSQPAELAARLKALNITADYEVIRAAET
                     GLVQIQARMGGTGERFFAGDATLTRAAVRLTDGTLGYSWVLGRDKQHAERCALIDALM
                     QQSRYFQNLSETLIAPLDADRMARIAARQAEVNASRVDFFTMVRGDNA"
     gene            complement(8239..8964)
                     /gene="phnF"
                     /locus_tag="RHX21_003879"
     CDS             complement(8239..8964)
                     /gene="phnF"
                     /locus_tag="RHX21_003879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate metabolism transcriptional regulator
                     PhnF"
                     /protein_id="HDV1989003.1"
                     /translation="MHLSTHPTSYPTRYQEIAAKLEQELRQHYRCGDYLPAEQQLAAR
                     FEVNRHTLRRAIDQLVEKGWVQRRQGVGVLVLMRPFDYPLNAQARFSQNLLDQGSHPT
                     SEKLLSVLRPASGHVADALGITEGENVIHLRTLRRVNGVALCLIDHYFADLTLWPTLQ
                     RFDNGSLHDFLREQTGIALRRSQTRISARRAQAKECQRLEIPNMSPLLCVRTLNHRDG
                     ESSPAEYSVSLTRADMIEFTMEH"
     gene            complement(8985..9764)
                     /gene="phnE"
                     /locus_tag="RHX21_003880"
     CDS             complement(8985..9764)
                     /gene="phnE"
                     /locus_tag="RHX21_003880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313113.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HDV1989004.1"
                     /translation="MQTITIAPPKRSWFSLLSWAVVLAVLVVSWQGAEMAPLTLIKDG
                     GNMATFAADFFPPDFSQWQDYLTEMAVTLQIAVWGTALAVVLSIPFGLMSAENLVPWW
                     VYQPVRRLMDACRAINEMVFAMLFVVAVGLGPFAGVLALFIHTTGVLSKLLSEAVEAI
                     EPGPVEGIRATGANKLEEILYGVLPQVMPLLISYSLYRFESNVRSATVVGMVGAGGIG
                     VTLWEAIRGFQFQQTCALMVLIIVTVSLLDFLSQRLRKHFI"
     gene            complement(9889..10905)
                     /gene="phnD"
                     /locus_tag="RHX21_003881"
     CDS             complement(9889..10905)
                     /gene="phnD"
                     /locus_tag="RHX21_003881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDV1989005.1"
                     /translation="MNAKIIASLAFTSMFSLSTLLSPAHAEEQEKALNFGIISTESQQ
                     NLKPQWTPFLQDMEKKLGVKVNAFFAPDYAGIIQGMRFNKVDIAWYGNLSAMEAVDRA
                     NGQVFAQTVAADGSPGYWSVLIVNKDSPINNLNDLLAKRKDLTFGNGDPNSTSGFLVP
                     GYYVFAKNNISASDFKRTVNAGHETNALAVANKQVDVATNNTENLDKLKTSAPEKLKE
                     LKVIWKSPLIPGDPIVWRKNLSETTKDKIYDFFMNYGKTPEEKAVLERLGWAPFRASS
                     DLQLVPIRQLALFKEMQGVKSNKGLNEQDKLAKTTEIQAQLDDLDRLNNALSAMSSVS
                     KAVQ"
     gene            complement(10930..11718)
                     /gene="phnC"
                     /locus_tag="RHX21_003882"
     CDS             complement(10930..11718)
                     /gene="phnC"
                     /locus_tag="RHX21_003882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709835.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HDV1989006.1"
                     /translation="MQTIIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKS
                     TLLRHLSGLITGDKSAGSHIELLGRTVQREGRLARDIRKSRANTGYIFQQFNLVNRLS
                     VLENVLIGALGSTPFWRTCFSWFTGEQKQRALQALTRVGMVHFAHQRVSTLSGGQQQR
                     VAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALR
                     YCERIVALRQGHVFYDGSSQQFDNERFDHLYRSINRIEENAKAA"
     gene            complement(11851..12294)
                     /gene="yjdN"
                     /locus_tag="RHX21_003883"
     CDS             complement(11851..12294)
                     /gene="yjdN"
                     /locus_tag="RHX21_003883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family metalloprotein YjdN"
                     /protein_id="HDV1989007.1"
                     /translation="MPLSPYLSFAGNCADAIAYYQRTLGAELLYKISFGEMPKSAQDS
                     AENCPSGMQFPDTAIAHANVRIAGSDIMMSDAMPSGKASYSGFTLVLDSQQVEEGKRW
                     FDNLAANGKIEMAWQETFWAHGFGKVTDKFGVPWMINVVKQQPTQ"
     gene            complement(12454..12789)
                     /locus_tag="RHX21_003884"
     CDS             complement(12454..12789)
                     /locus_tag="RHX21_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phnA family protein"
                     /protein_id="HDV1989008.1"
                     /translation="MSLPHCPKCNSEYTYEDNGMYICPECAYEWNDAEPAQESDELIV
                     KDANGNLLADGDSVTIIKDLKVKGSSSMLKIGTKVKNIRLVEGDHNIDCKIDGFGPMK
                     LKSEFVKKN"
BASE COUNT         2576 a         3655 c         3921 g         2837 t
ORIGIN      
        1 caaatactga gcacaattta tcaatgcaac cggtgtttct ttttaaaaaa cgtaccggag
       61 caatgggcgg tcatgtcgct ggcaccgcag gattctgcgt tgctgtgcca gccttttatt
      121 catggtcaat gagtgaggtg attgataaag acaccaggtc gtcagagcgc actgattatc
      181 cgcattatgc cagtgaagtt gcactggctt ttggttcacg agtggttggc ctcgaactgg
      241 caaaaatgat tgtggatgcg tggctgggcg cacagtacga aggcggtcgt catcaacaac
      301 gcgtggaggc gattacggca atagagcagc ggagaaattg agattcatcc actacttgca
      361 tggatgagta atgactaatg tggatagagt ttctttttga ggttggctaa tgaaacgctt
      421 tccgctattt cttttattca ccctgctcac gctgtccacc gttccggccc aggctgatat
      481 tatcgacgat actattggta atattcagca ggcgattaat gacgcttata accctgaccg
      541 tgggcgagac tatgaagatt cgcgcgacga cggctggcag cgtgaagtga gcgacgatcg
      601 gcgcagacaa tatgacgacc gccgccgcca gtttgaagat cgccgcaggc agctggacga
      661 tcgccagcgc cagcttgatc tggagcgtcg gcaactggag gatgaagagc ggagaatgga
      721 agatgagtat gggcgatgag gttgggtatg gagcaggcat cgcccctcac cccaatgggg
      781 agagggagaa aacgagcgca atattcaata ttgagcacaa tcggtcccct cgcccctctg
      841 gggagagggt tagggtgagg gggccagcgc gcacattccc tctcatcacg ccaccccaat
      901 ctccatccca tcaaacccca cctcaaaccc tgacggtagt gcgttttcca tcagccacgc
      961 atcaaactgg tggctgatat gggtcagaat cacctgtggc gagcggataa cctgattcag
     1021 cgcaagcacg gtatttaaat cacagtgatt acgcggtgca tccgcgcgcg gcgggtgact
     1081 gcaatcaatc accatcacct gcggatgatt attgagtaaa aatttcagcg ttttttccgg
     1141 caggccagcg gtgtcagaca gccacgccac ccggctatgt gccgtttcca gcagataacc
     1201 gaaggtcagt tttgagtggt taagcggcag cggcgtgacc tgcaacccct gcaaatcaaa
     1261 caccacaaac ggttccactg tgtggctgaa atcaagcagg cccggatgtt taaacagatc
     1321 gtcgcagccc tgttcatccg gcgggccgta gaccgggatc acatcgccca cgccccagcg
     1381 tagcggaaat agcccttgga cgtgatccat atggtagtgc gtcagcaaaa actgctggaa
     1441 cgatccaggc gaccagcgat cggtgagatc gtgccgcccg gcgtcgatca gggtgatcgc
     1501 gtcgttaaac ttcactacgc cgctgcatgg ctggcggcga tactgcggcg agcgccgcgc
     1561 tctggcgcag gccgcgcact cgcagcccca tgccggaacg ccctgtgcgc cgccagtgcc
     1621 ggtgagcgtg agggtcaggc tcatgttaca gcgccttggt gaagcggaag tggctctgct
     1681 cgtagccttc acgcaggtaa aaacggtgtg cgtcgtggcg cttcacgttg gtggaaagct
     1741 cggtcatttc ggccccggcc tggcgggctt cttcttctgc ccatgccagt aatttactgc
     1801 cgacgttcag accgcgcgcc tgcggcatca ccaccagttc ctgaatttcg ccgatccagt
     1861 tgacatgatg cagatgaaac tgcaaatgca ggccgatcat gccgacaact tcgccatcca
     1921 gcagcgccag atggtagcgc atgtttgggt cgcgcaggtt ggcgttaaag cccacgcgaa
     1981 acgcatggtg gtcaaactcc gcctgtttta gctcacaaat cagcgcgtaa accgcgtcgg
     2041 tatcgtactg cgtggccggg cgaagctcac aagcaggcat ggtgtttctc cttctgatgg
     2101 atcagcgtca gcagcgtgtc gaccgactgg cgcaggctgc cgtcattgtt gagcgtatgg
     2161 caatcctgtg gagtatagcg ggcggcgcgc gccaggcggg cgttaatttc actggcgttt
     2221 tcacggccac ggttttccag gcgctggcgc aggatctccg gcgaaacctg taaacagacg
     2281 ggcagcagcg ccgattgata gcgcgcccgt gcctgcggca aatgcgcgcg tgaaccgttg
     2341 acgactacgt cgaatccagc gtgcagccag aggtcaatct cgatgccgac gccataatac
     2401 agaccgttag cgtgccagct taaggccagc aggttttgcc ccgcgcgggt aaaaaactcc
     2461 cgctcactca gggcgatatg gttttcactt ccggcgctgg cgtcgcgcgt gatgtagcga
     2521 tgcgccacca gtaactgcgt ttgttcccgc aggcggagtt ccgccagcag gctgtctttc
     2581 ccggagccgg acggccccat taaccaaatc agttttccca tcatcagaac acccttttac
     2641 cctgacgcca gacgtggtcg atatgaatgt gattgccctg gcgatgcgcc agcaccaggt
     2701 cagcgcgttt accctcgcca atcaccccgc gatcctgaag attcagcgcc tgcgccggat
     2761 ttttggtcac cagcctcacc gcctgcggta gcgtaaagcg gttgctctcg tcatcggcga
     2821 cgcggaacgc cgcatccagc aggctggctg ggtagtagtc ggaagagagg atatccagca
     2881 gaccaagctg cgccagttca ctggccgcca cattgccgga gtgcgagccg ccacgcacga
     2941 tatttggcgc acccatcagc acgttcatgc catgcttacg cgaggcttcc gccgcttcga
     3001 acgtggtggg aaattcggcg atcacgctgc caagttggtg ggattcggca acgtgggcgt
     3061 gcgtggcgtc atcgtggctg gcgagcgcaa tttgtcgcgc gcggcacagg gcggcgatgg
     3121 attcgcgatt cggctgcgac cagcgtgcgg cgagcgccaa ttgctcttct tcgtactgct
     3181 gcatctgcgc atcggtgagg gagtatttgc cctgataata ttcgcgatac ttctcgcggt
     3241 tagcgaactg gcgctggccc ggtgagtggt ccatcagcga caccagcgtc accggttcgc
     3301 gctgaaccag tttttcaaac agcggcagtg tggtgtgatg cggcagctcg cagcgcaggt
     3361 gcagacggtg ctcggcgcgg ttgacgccgc gtttctgcgt ctcttcgatg gtgttgatca
     3421 tcttctccag attctccagc cgatcgccgc cgtcgcgcac gtcgccaatc gccaccgcgt
     3481 ccagcacggt ggtgatgccg cttgccacca tcagcgcgtc gtggctgctc atcgccgaat
     3541 gggcgggcca gtcgactttc gggcgcgggg tgaagaattt atcgaggttg tcggtatgca
     3601 gctcaatcag gccgggtagt agccagccac cttcgccgtc catcgcttct ggcaggcggc
     3661 tctggctttc ggcaaaggcg cggatttcgc catcctgcac ctccagcgaa ccgtgtacca
     3721 cttcgttttc cagcaccagt ttgacgttat tgataatcat gcagaggctc ccattgggtg
     3781 caagcggtcg gcgacgtcat tacgtacggc ttcgtcatgg aagatgccga cgatggccgc
     3841 gccacgggtt ttggcttcgc gaatcagctc gactacggcg gcgctgtttt tggcgtccag
     3901 cgaggcggta ggttcgtcga gcagcagaat ggggtagtcg acgataaagc cgcgggcgat
     3961 gttgacgcgc tgctgttcgc caccggaaaa ggttgatggc gccaggtgcc acaggcgttc
     4021 cggcacgttc aggcgggtga gcagacgcgc ggctttagcg gcgcaggctt cacgcggaac
     4081 gccggtatcg agcagcggct gcatcaccac ttccagtgct gaaatacgcg ggatgacgcg
     4141 cagaaactgg ctcacccagc cgacggtggt tttgcggatc tccaccactt tgcgggctgg
     4201 cgcggtgacc aggtctaccc actcgtcacc gtgtttgatc tggatttgac cttcatcggg
     4261 cagatagttg gcgtacagcg agcgcagcag ggttgatttg ccgctgccgg agtgaccgtg
     4321 gagcaccacg cattcgcccg cgttgacggt gagcgaggcg cggttgagga cgggcaggcg
     4381 cacgccgttt tgctggtgca ggatgaaggt tttactgacg ttttgtacgt taatcatttt
     4441 tcgcctcgtg gttcgggtgt cggatgcgac gctgacgcgt cttatccgac ctacggggag
     4501 cgcatttgta ggccggataa ggcgtttacg ccgcatccgg caccggctca attctgcaaa
     4561 accgatgaca ccagcagctg tgtatacgga tgatgcgggt cgtcgagcac gcggtcggtt
     4621 aacccactct ccaccacttg cccctgcttc atcaccagca aacggtccgc cagcaggcgg
     4681 gcaacgccta aatcatgggt gacaatcacc accgccaggt tcagctccac caccaggccg
     4741 cgcagcaggt cgagcaggcg ggcctgcacc gacacatcca gcccgccggt cggttcatcc
     4801 ataaacacca gcttcggatg cgtcaccagg ttgcgggcaa tctgcaaacg ttgctgcatg
     4861 ccgccggaaa aggtggtcgg caggtcgtcg atccggttgg cgggaatttc cacctcttcc
     4921 agccacttct gcgcggtggc acgaatatcg ccgtaatgac gtgccccggt cgccatcagc
     4981 cgctcgccga tattgccgcc tgccgacacc tggcggcgca ggccgtcgag cggatgctga
     5041 tgcactacgc cccattcggt gcgcagcagg cgacggcggt cggcctcgct cattgcgtac
     5101 agcgaacggc tctcatagtg aatctccccc tgctgcggcg tcaggcgcgc ggagattgat
     5161 ttcagcagcg tggtcttccc ggagccggac tccccgacaa tgcccagcac ttcccccggc
     5221 cataaatcaa aagagacatc gctaaagcct ttgcccggcg cgtaaaggtg ggtcaggtta
     5281 ttgaccgaaa gtaacggttg attcattggc ttttcgcctc gctctgttgg cggcaataat
     5341 cggtatcgga gcagacaaac atgcggtttc cggcgtcatc cagcaccact tcatcaagat
     5401 agctgtgggt cgatccgcag atggcgcatg gctcatccca ctgctgaacg gtgaacgggt
     5461 gatcgtcgaa atcgagactt tccacgcggg taaacggcgg caccgcatag atgcgcttct
     5521 cgcgccccgc gccgaacagt tgcagggcgg gcatcatgtc catttttggg ttatcgaatt
     5581 tcgggatcgg cgacgggtcc attacgtagc gcccgttcac cttcaccgga taggcgtagg
     5641 tagtggcgat atgaccgaag cgggcgatat cttcatacag tttcacctgc atcacgccgt
     5701 actcttccag cgcgtgcatg gtgcgggttt ccgtttcgcg cggctcgata aagcgcagcg
     5761 gttccgggat tggcacctgg aagataatga tctgatcttc ggtcagcggc gtttcgggga
     5821 tgcggtgacg cgtctggata agcgtcgcat cgtccgtacg ttcagtggtg tttaccccgg
     5881 tcacgcgctt aaagaagttg cgaatcgaca cggcgttggt ggtgtcatcc gcaccctggt
     5941 caatcacctt cagcacgtcg ctttcgccaa tcacgctggc ggtgagctgt atgccgccgg
     6001 ttccccagcc gtatggcatc ggcatctcgc gcccgccaaa cggcacctga taaccgggga
     6061 tcgccaccgc ttttaagata gcgcggcgga tcatgcgttt ggtctgctcg tcgaggtagg
     6121 caaagttgta gccgctcaga ttagccatgg ttcttctcct gttgcagacg tttgagtagc
     6181 tccagttcgg cctggaaatc gacgtagtgg gggagtttga ggtgcgagac aaagcctgcg
     6241 gcttcgacgt tgtcggcatg tgccagcaca aactcttcat cctgcgccgg gcctgtcgcg
     6301 tgctcgccgt attccggagc ctgcaacgca cgatcgacca gcgccattgc catcgctttg
     6361 cgctcgctca tgccgaatac cagcccgtag ccgcgcgtga agtgcggcgg ctcatccggc
     6421 gggtcgataa aaccgttgac catttcacac tcggtcatca gtagttcgcc gacgtttacc
     6481 gcaaatccca gctcttccgg cacaatcgac acgtcgatgt aaccactgcg gatctcgccc
     6541 gcgaacgggt gattgcgccc gtaaccacgc tgggtggagt aggccagcgc cagcaaatag
     6601 ccttcgtccc cgcgcattaa ttgttgcagg cgggaggagc gtgagcaggg gtaaaccggc
     6661 ggcgtgcggg tgatgtcatc cggctgtgcg ccgctatctt cttcaaactt caccagcccc
     6721 tgacgcgcca gcaggctgaa aacgtgcggc gacggctgtt gttcgctgtc ggcggtggtc
     6781 agcgtcggcg cttcaccgtt tgccagcagg gtgaaatcga gcaggcgatg ggtgtagtcg
     6841 taggttgggc caagcagctg gccgccggga atgtctttat aaaccgccga aatacgccgt
     6901 tcgagacgca tctctgtggt gtcgagcggc tcgcttaccg cgagcttcgc cagcgtggtg
     6961 cggtaggcgc gcagcaggaa aattgcttcg acgttatcgc cgctggcctg tttcagcgcc
     7021 agcgccgcca gttcgcggtc ggcaatgccg ccttcggtca tcacgcgatc caccgcaaga
     7081 ttaagctgct gttcaatctg ggcgacgctc agttcaggca aatcggtatc gccccggcgt
     7141 cggctctctt gcagggcgtg agcggcgtcg atcgccttct cgcccccttt cacggcaacg
     7201 tacatcagca cacctccaca tgagtggttc gcggaatagc cagcaggcgc tcgccgcagg
     7261 tcaggatcag gtcgatgccg agcgggaacg ggtgcgggcg ctcggtgagt tcgtgcagaa
     7321 tgcactccgg cagctgcgga gcgatcattc gttcttcggc aatgcccgcg ccggtgagac
     7381 gtaacatgcg cccgccgctc aggctggcga cctgtaaaat cagcgttgca cccgcttccg
     7441 gcgcaacggc ggtgccggtg gaaagggcgt taagctgttc gctggaaatc gcctcatccg
     7501 tcaccgcgaa ggtcgcctgt tccggctggc tgaccagcgg cgcgttggta tgaaaacgca
     7561 ggctctggct gacgatatcg ttactcaatg gcgcggcaag ccacaccggc gtgtcgttat
     7621 cggccagcgt cagcagcacg ctggtggtgg cgatattcag cggctgccag ccgcgcttga
     7681 gctgatgcag ggcgacaatc acgcccggct cgctcatggc ctttaacagg cgacgaaaac
     7741 tgtgctgggc atcctgcacg ggaagcataa aagcggtttc cagggtcatg cgttgtctcc
     7801 gcgaaccatc gtaaagaagt cgacccggct ggcgttcact tcggcctggc gtgcggcaat
     7861 gcgtgccata cggtcagcgt ccagcggggc aataagggtt tctgataagt tttgaaaata
     7921 gcgagattgc tgcatcagcg cgtcaatcag cgcgcagcgt tcggcgtgct gtttgtcgcg
     7981 ccccagcacc cagctgtagc cgagcgtgcc gtcagtcagg cgtacggcgg cgcgggtgag
     8041 cgtggcgtcg ccggcaaaaa agcgttcgcc ggtgccgccc atccgcgcct gaatctgcac
     8101 caggccggtt tcggcggcgc ggataacctc atagtcggcg gtgatgttca gtgctttcag
     8161 gcgggctgcc agttcagccg gttggctgtg cgccagtacg gacatccagt gctggcgggt
     8221 cgcggtatct gcgtgcattc agtgctccat agtgaattca atcatgtcgg cgcgcgtcag
     8281 gctgacggag tactccgccg ggctgctttc accgtcacgg tggttaaggg tgcgcacgca
     8341 cagcagcggc gacatattcg gaatttcaag acgctggcac tctttggcct gggcgcgacg
     8401 ggcgctgatc cgcgtctggc tgcggcgcag cgcaattccg gtttgctcgc gcagaaaatc
     8461 gtgcagcgaa ccgttgtcga agcgttgcag cgtcggccaa agggtgaggt ccgcaaagta
     8521 gtggtcgatt aaacagagcg cgacgccgtt gacgcgacgc agggtgcgca aatggataac
     8581 gttctcgccc tcggtaatcc ccagcgcgtc agcgacgtga ccggacgcgg ggcgcaatac
     8641 cgacagcagt ttttcgctgg tgggatggct accctggtcc agcaggttct ggctaaaacg
     8701 cgcctgggcg ttgagcgggt aatcgaacgg gcgcatcagc accagcacgc cgacgccctg
     8761 acggcgctgt acccagcctt tttccaccag ttggtcgatg gcgcggcgca gggtgtggcg
     8821 gttcacctca aagcgcgccg ccagttgctg ctcggcggga agatagtcgc cgcagcggta
     8881 gtgttgacga agctcctgct caagttttgc ggctatctcc tgatagcgtg ttgggtagct
     8941 ggtcggatgt gtagacaagt gcatagatat caatgcctcg cttatcagat aaagtgctta
     9001 cgcaaccgtt gagagaggaa atccagcagg ctgaccgtga cgatgataag caccatcagg
     9061 gcgcaggttt gttggaactg gaaaccgcga atcgcttccc acagggtgac gccgatcccg
     9121 cctgcgccga ccatgccgac gacggtcgcc gagcggacgt tggattcgaa gcgatagagg
     9181 gagtaggaga tcagcagcgg catcacctgt ggcagcacgc cgtagaggat ctcttcgagc
     9241 ttgttggcac cggtggcgcg aatgccttcc accgggccgg gttcaatcgc ttccaccgcc
     9301 tcggaaagca gcttggagag cacgccggtg gtgtggataa atagcgccag cacgccagcg
     9361 aacggtccga gaccgacggc gaccacgaac agcatggcga agaccatttc gttaatggcg
     9421 cggcaggcgt ccatcaggcg gcgaacgggc tggtaaaccc accacggcac caggttttcg
     9481 gcgctcatca ggccgaaggg gatggagaga accactgcca gcgcggtgcc ccagacggcg
     9541 atttgcagcg tgacggccat ttcggtgagg taatcctgcc actggctgaa atcgggcggg
     9601 aagaagtcgg cagcgaaggt tgccatgttg ccgccgtctt taatcagcgt aagcggggcc
     9661 atttccgcgc cctgccacga gacgaccagc acggcgagaa caacggccca gctcagaagc
     9721 gagaaccagc tacgcttggg tggggcgatg gtgatggttt gcatgtttgg ctccgtttaa
     9781 tgttttctcc ctctccctgt gggagagggc cggggtgagg gcatcagcgt gcgcattccc
     9841 cctcacccta accctctccc tcaagggaga ggggaccgat cgagcacatt actgcaccgc
     9901 tttactcacc gaactcatcg cgcttaacgc gttgttcagg cggtccaggt catccagctg
     9961 cgcctgaatc tcggtggttt tcgccagctt gtcctgctca ttcagtcctt tattgctttt
    10021 tacgccctgc atctctttaa acagtgcgag ctggcgaatc ggcaccagtt gcaggtcgct
    10081 ggaagcgcgg aacggcgccc agcccaggcg ttccagcacc gctttttctt ccggcgtttt
    10141 gccgtagttc ataaagaagt cgtagatctt gtctttggtg gtttcggaaa ggtttttacg
    10201 ccagacgatc ggatcgcctg ggatcagcgg cgacttccag atcactttca gttctttcaa
    10261 cttctccggc gcggaggttt tcagcttgtc gaggttttcg gtgttgttag tggcaacatc
    10321 cacctgcttg ttggcgacgg ccagcgcgtt ggtttcatgc ccggcgttga cggtgcgctt
    10381 gaagtcgctg gcggagatat tgtttttggc gaagacgtag tagccgggga cgaggaagcc
    10441 agaggtggag ttaggatcgc cattgccgaa ggtgagatct ttccgcttcg ccagcagatc
    10501 gttcaggttg ttgatcggac tatctttgtt gacgatcaac acgctccagt aacccggcga
    10561 tccgtccgcc gcgacggttt gggcgaagac ctggccgttg gcgcgatcca ccgcttccat
    10621 tgccgacagg ttgccgtacc aggcgatatc cactttattg aagcgcattc cctggataat
    10681 gcctgcgtag tctggggcaa agaaggcgtt caccttcacg cccagcttct tctccatatc
    10741 ctgtaagaat ggcgtccatt gcggtttcag gttttgctgt gattccgttg aaataatgcc
    10801 gaaattcagc gccttttcct gctcttcggc gtgtgccggg cttaacaggg tgctgaggct
    10861 gaacatgctg gtgaaggcca gcgaggcaat tatcttagcg ttcattcgtt ttcctcaatg
    10921 atggggatgt caggcagctt tcgcgttctc ttcgatgcga ttaatgctgc ggtagagatg
    10981 gtcaaaacgt tcgttatcaa actgttgact gctgccgtcg tagaaaacgt gcccctggcg
    11041 cagggcgacg atgcgttcgc agtagcgcag ggcgtaatcc acctgatgta gcgtgacgac
    11101 cacggtgatg ccgtcgttct ggttgatgtc gcgcagggtg tccatcacga tgcgggcgga
    11161 ttccgggtcc agcgaggcga tgggttcatc ggccagaatc accttcgcct gctgcatcag
    11221 cgcgcgggca atcgccacac gctgctgctg tccgccggag agggtggaaa cgcgctgatg
    11281 ggcaaaatgc accatgccaa cgcgggtcag cgcctgtaac gcgcgctgtt tctgctcgcc
    11341 ggtgaaccag ctaaaacagg tgcgccagaa cggcgtgctg ccgagcgcgc caatcagcac
    11401 gttctccagt acgctcaggc ggttcaccag gttgaattgt tggaagatgt agccggtgtt
    11461 ggcgcggctt ttgcggatat cgcgcgccag acggccttcg cgctggactg tgcggcccag
    11521 cagctcgata tggctgccgg cggatttatc gccggtaatc aaaccgctta agtgacgtaa
    11581 aagggtggat ttgccggaac ccgacggccc aagcagagcc accatttcac cgtgatgaat
    11641 gttcagatca accgcatgca gcgcctgatg ctgattgaag gttttggcga gcttctcgac
    11701 acggataatc gtttgcatga tgcagcctcc ctaaaaaagt ggctccatcg tggcggatta
    11761 ttgtgacgat ttggttaatt aaaagtgact aacagatgaa gagttaacgg gaattcgatg
    11821 acagtgcggg agggcgggcc tcccggcgga ttattgcgtt ggttgttgtt tgacgacatt
    11881 aatcatccac ggtacgccaa atttatcggt gactttgcca aagccatgcg cccagaaagt
    11941 ttcctgccag gccatttcga tttttccgtt agcggcaaga ttgtcaaacc agcgttttcc
    12001 ttcttcgacc tgttgcgaat cgagcaccag cgtaaagccg gagtagctgg cttttcctga
    12061 cggcatggca tcgctcatca tgatgtcgct tccggcaatg cgcacgttgg catgagcgat
    12121 ggcggtatcg ggaaattgca ttccggaagg gcagttctcg gcgctgtcct gcgctgattt
    12181 tggcatttcg ccgaagctga ttttatagag cagttcagcg cccaacgtac gttgataata
    12241 agcaattgcg tcggcacagt taccggcaaa agagaggtag ggacttaacg gcatgatggt
    12301 gacctcagtt aagagaagcc agttaagtgt agttcgaaat ttatacagat gagagggaag
    12361 cctgataaga cgcggtcagc gtcgcatcag gcagtcggca tcgttgccgg atgcggcgcg
    12421 agcgccttat ccggcttacc gatcacaata caatcagttc tttttcacaa actcagattt
    12481 cagtttcatc ggaccaaaac cgtcgatttt gcaatcgatg ttatggtcgc cttcaaccag
    12541 gcggatgttt ttcactttgg tgccaatttt cagcatcgaa gagctacctt tcaccttcag
    12601 atctttaatg atggtaacgc tgtcgccgtc agccagcaga ttgccgttag catctttaac
    12661 gatcagctcg tcgctttcct gtgcaggttc tgcgtcgttc cattcgtagg cacattccgg
    12721 gcagatgtac atgccgttat cttcgtaagt gtattcggag ttgcattttg ggcagtgtgg
    12781 taatgacatg tggatttcct caaaagtcag cagggcaaaa gcgccaaaaa acggcagatt
    12841 gccgaaaaag gccgcaatta tacacaaaat ccctgagttt gtcgggggta ctgctgattt
    12901 tagacgacga tcgttttcat ttgaaaggaa acgcaaaaag aaaataatct ttttgcctct
    12961 atttattatt taagataatg ttaatgctc
//
LOCUS       DAPGUL010000128        12970 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.130, whole genome shotgun sequence.
ACCESSION   DAPGUL010000128 DAPGUL010000000
VERSION     DAPGUL010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12970
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.130"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(495..1586)
                     /gene="ychF"
                     /locus_tag="RHX21_003885"
     CDS             complement(495..1586)
                     /gene="ychF"
                     /locus_tag="RHX21_003885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001538644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HDV1989009.1"
                     /translation="MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVV
                     PMPDPRLDQLAEIVKPQRTLPTTMEFVDIAGLVKGASKGEGLGNQFLTNIRETEAIGH
                     VVRCFENDNIIHVSGKVNPADDIEVINTELALADLDTCERAIHRVQKKAKGGDKDAKA
                     ELAVLEKCLPQLENAGMLRALDLSAEEKAAIRYLSFLTLKPTMYIANVNEDGFENNPY
                     LDQVREIAAKEGSVVVPVCAAVEADIAELDDEERDEFMQELGLEEPGLNRVIRAGYKL
                     LNLQTYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAQTISFEDFITYKGEQ
                     GAKEAGKMRAEGKDYIVKDGDVMNFLFNV"
     gene            complement(1703..2287)
                     /gene="pth"
                     /locus_tag="RHX21_003886"
     CDS             complement(1703..2287)
                     /gene="pth"
                     /locus_tag="RHX21_003886"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HDV1989010.1"
                     /translation="MTIKLIVGLANPGAEYAATRHNAGAWFVDLLAERLRAPLREEAK
                     FFGYTSRVTLGGEDVRLLVPTTFMNLSGKAVAAMASFFRINPDEILVAHDELDLPPGV
                     AKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRIGIGHPGDKNKVVGFVLGKPPVSEQK
                     LIDEAIDEAARCTEMWFTDGLTKATNRLHAFKAQ"
     gene            2565..2843
                     /gene="ychH"
                     /locus_tag="RHX21_003887"
     CDS             2565..2843
                     /gene="ychH"
                     /locus_tag="RHX21_003887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress-induced protein YchH"
                     /protein_id="HDV1989011.1"
                     /translation="MKRKNASLLGNVLMGLGLVVMVVGVGYSILNQLPQFNMPQYFAH
                     GAVLSIFVGAILWLAGARVGGHEQVCDRYWWVRHYDKRCRRSDNRRHS"
     gene            complement(2898..4577)
                     /gene="dauA"
                     /locus_tag="RHX21_003888"
     CDS             complement(2898..4577)
                     /gene="dauA"
                     /locus_tag="RHX21_003888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415724.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylic acid transporter DauA"
                     /protein_id="HDV1989012.1"
                     /translation="MNKIFSSHVMPFRALIDACWKEKYTAARFTRDLIAGITVGIIAI
                     PLAMALAIGSGVAPQYGLYTAAVAGIVIALTGGSRFSVSGPTAAFVVILYPVSQQFGL
                     AGLLVATLLSGIFLILMGLARFGRLIEYIPVSVTLGFTSGIGITIGTMQIKDFLGLQM
                     AHVPEHYLQKVGALFMALPTINVGDAAIGIVTLGILVFWPRLGIRLPGHLPALLAGCA
                     VMGIVNLLGGHVATIGSQFHYVLADGSQGNGIPQLLPQLVLPWDLPNSEFTLTWDSIR
                     TLLPAAFSMAMLGAIESLLCAVVLDGMTGTKHKANSELVGQGLGNIIAPFFGGITATA
                     AIARSAANVRAGATSPISAVIHSILVILALLVLAPLLSWLPLSAMAALLLMVAWNMSE
                     AHKVVDLLRHAPKDDIIVMLLCMSLTVLFDMVIAISVGIVLASLLFMRRIARMTRLAP
                     VVVDVPDDVLVLRVIGPLFFAAAEGLFTDLESRLEGKRIVILKWDAVPVLDAGGLDAF
                     QRFVKRLPEGCELRVCNVEFQPLRTMARAGIQPIPGRLAFFPNRRAAMADL"
     gene            complement(4702..5649)
                     /gene="prs"
                     /locus_tag="RHX21_003889"
     CDS             complement(4702..5649)
                     /gene="prs"
                     /locus_tag="RHX21_003889"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HDV1989013.1"
                     /translation="MPDMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQI
                     NENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVR
                     SARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLN
                     LDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVL
                     VDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIP
                     LSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFEH"
     gene            complement(5800..6651)
                     /gene="ispE"
                     /locus_tag="RHX21_003890"
     CDS             complement(5800..6651)
                     /gene="ispE"
                     /locus_tag="RHX21_003890"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HDV1989014.1"
                     /translation="MRTQWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTISIE
                     LRDDGDIRLLTPVEGVEHEDNLIVRAARLLMKTAADSGRLPTGSGANISIDKRLPMGG
                     GLGGGSSNAATVLVALNHLWQCGLSMDELAEMGLTLGADVPVFVRGHAAFAEGVGEIL
                     TPVDPPEKWYLVAHPGVSIPTPVIFKDPELPRNTPKRSIETLLKCEFSNDCEVIARKR
                     FREVDAVLSWLLEYAPSRLTGTGACVFAEFDTESEARQVLEQAPEWLNGFVAKGVNLS
                     PLHRAML"
     gene            complement(6651..7274)
                     /gene="lolB"
                     /locus_tag="RHX21_003891"
     CDS             complement(6651..7274)
                     /gene="lolB"
                     /locus_tag="RHX21_003891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein localization protein LolB"
                     /protein_id="HDV1989015.1"
                     /translation="MPLPDFRLIRLLPLAALVLTACSVTTPKGPGKSPDSPQWRQHQQ
                     DVRNLNQYQTRGAFAYISDQQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGN
                     VQLVDNKGQRYTADDAEEMIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEI
                     TYSQNGKNWKVVYGGYDTKTQPAMPANMELTDGGQRIKLKMDNWIVK"
     gene            7488..8744
                     /gene="hemA"
                     /locus_tag="RHX21_003892"
     CDS             7488..8744
                     /gene="hemA"
                     /locus_tag="RHX21_003892"
                     /EC_number="1.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_041689438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA reductase"
                     /protein_id="HDV1989016.1"
                     /translation="MTLLALGINHKTAPVSLRERVSFSPDKLDQALDSLLAQPMVQGG
                     VVLSTCNRTELYLSVEEQDNLQEALIRWLCDYHNLNEEDLRKSLYWHQDNDAVSHLMR
                     VASGLDSLVLGEPQILGQVKKAFADSQKGHMKASELERMFQKSFSVAKRVRTETDIGA
                     SAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRER
                     AQILADEVGAEVIALSEIDERLREADIIISSTASPLPIIGKGMVERALKSRRNQPMLL
                     VDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRKAAAVEAETIVAQETSEFMA
                     WLRAQSASETIREYRSQAEHVRDELTAKALAALEQGGDAQAIMQDLAWKLTNRLIHAP
                     TKSLQQAARDGDNERLNILRDSLGLE"
     gene            8786..9868
                     /gene="prfA"
                     /locus_tag="RHX21_003893"
     CDS             8786..9868
                     /gene="prfA"
                     /locus_tag="RHX21_003893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012132158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HDV1989017.1"
                     /translation="MKPSIVAKLEALHERHEEVQALLGDAQTIADQERFRALSREYAQ
                     LSDVSRCFTDWQQVQEDIETAQMMLDDPEMREMAQDELREAKEKSEQLEQQLQVLLLP
                     KDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSASEGEHGGYK
                     EIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPDAELPDIN
                     PADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGA
                     RIHAAEMAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVME
                     GKLDMLIEPIIQEHQADQLAALSEQE"
     gene            9868..10701
                     /gene="prmC"
                     /locus_tag="RHX21_003894"
     CDS             9868..10701
                     /gene="prmC"
                     /locus_tag="RHX21_003894"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HDV1989018.1"
                     /translation="MEYQHWLREAISQLQASESPRRDAEILLEHVTGRGRTFILAFGE
                     TQLTDEQCQQLDALLTRRRDGEPIAHLTGVREFWSLPLFVSPATLIPRPDTECLVEQA
                     LARLPEQPCRILDLGTGTGAIALALASERPDCEIIAVDRMPDAVSLAQRNAQHLAIKN
                     IHILQSDWFSALAGQQFAMIVSNPPYIDEQDPHLQQGDVRFEPLTALVAADSGMADIV
                     HIIEQSRNALVSGGFLLLEHGWQQGEAVRQAFILAGYHDVETCRDYGDNERVTLGRYY
                     Q"
     gene            10698..11090
                     /locus_tag="RHX21_003895"
     CDS             10698..11090
                     /locus_tag="RHX21_003895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SirB family protein"
                     /protein_id="HDV1989019.1"
                     /translation="MTSFSTLLSVHLISLALSVGLLTLRFWLRYQKHPQAFARWTRIV
                     PPVVDTVLLLSGIALMAKAHILPFSGQAQWLTEKLFGVIIYIVLGFIALDYRRMHSQQ
                     ARIIAFPLALVVLYIIIKLATTKVPLLG"
     gene            11094..11903
                     /locus_tag="RHX21_003896"
     CDS             11094..11903
                     /locus_tag="RHX21_003896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat-containing protein"
                     /protein_id="HDV1989020.1"
                     /translation="MRSLADFEFNKAPLCEGMILACEAIRRDFPSQDVYDELERLVSL
                     AKEEISQLLPLEEQLEKLIALFYGDWGFKASRGVYRLSDALWLDQVLKNRQGSAVSLG
                     AVLLWVANRLDLPLLPVIFPTQLILRIECPDGEIWLINPFNGESLSEHMLDVWLKGNI
                     SPSAELFYEDLDEADNIEVIRKLLDTLKASLMEENQMELALRTSEALLQFNPEDPYEI
                     RDRGLIYAQLDCEHVALNDLSYFVEQCPEDPISEMIRAQINNIAHKHIVLH"
     gene            11939..12793
                     /gene="kdsA"
                     /locus_tag="RHX21_003897"
     CDS             11939..12793
                     /gene="kdsA"
                     /locus_tag="RHX21_003897"
                     /EC_number="2.5.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-8-phosphooctulonate synthase"
                     /protein_id="HDV1989021.1"
                     /translation="MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTV
                     TQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQA
                     QPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGN
                     EKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRR
                     AQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKG
                     FEELDTSK"
BASE COUNT         3237 a         3274 c         3357 g         3102 t
ORIGIN      
        1 gtatctgcat aacaaaaaca atatgcgcca tttttgcatt actaataaga aaaagcaaaa
       61 aacatcgata ttcatttttg gtcaatgggt tttctggcct atcgttgtta ttgtgctact
      121 ggttatcatt ttcatcttgc caggatcgca cgtaatcacg ttattcgggg actttatctg
      181 cgggatatta cccttcaggt aagtcctttt ctcgccagca tattggagcg tgatcaatat
      241 tgatcagctg tgaagggggt gatgtgtagt ggaccaaaac ttacgttata tcactactaa
      301 tgagatatcc gtcatctgac actgatgtct ttaattattc tcgtggttca ctgtaggcaa
      361 taagcacaaa agtgtaggat gttacaagaa tgattaggac tcggtgaaat gaaaaatcca
      421 cgcaattgcg tggattatat atacttttgc gctcttcatg agatttagcg aaacctcatg
      481 agacaacaaa ttaattagac gttgaaaagg aagttcatca catcgccatc tttaacgatg
      541 taatctttac cttctgcacg cattttgcct gcttctttcg cgccttgttc acctttgtaa
      601 gtgatgaaat cttcaaacga gatggtttgt gcacggataa agcctttttc aaaatcagta
      661 tggattttgc ccgctgcctg cggcgcggtt gctccaaccg gaatggtcca tgcacgcact
      721 tctttcaccc cagcggtgaa gtaagtttgc aggttcagca gcttataacc ggcacggatc
      781 acacggttca ggcccggctc ttccagccca agctcctgca taaactcgtc acgttcttcg
      841 tcgtccagtt cggcaatgtc tgcttcaaca gcagcacaaa ccggaaccac aacagaacct
      901 tctttcgccg cgatttcacg cacctggtca agatatgggt tgttttcaaa accgtcttcg
      961 ttgacgttgg cgatgtacat tgttggtttc agcgtcagga agctcaggta acgaatagcc
     1021 gctttctctt cagcgcttaa atccagcgcg cgcagcatac ctgcattttc caactggggc
     1081 aggcattttt ccaggaccgc cagctcagct ttcgcgtctt tatcgccacc tttggctttc
     1141 ttctgtacgc gatgaatcgc acgttcgcag gtgtcgaggt ctgccagcgc cagttcggtg
     1201 ttgataactt caatatcgtc agccgggtta actttgccgg aaacgtgaat gatgttgtca
     1261 ttttcaaagc agcgaacaac gtgaccgatc gcttcggttt cacggatgtt ggtcaggaac
     1321 tggttaccca gaccttcgcc tttcgatgcg ccttttacca gaccggcgat atcgacaaat
     1381 tccatggtcg tgggaagcgt acgttgcggt tttacgattt cagccagttg atccaggcga
     1441 gggtcaggca ttggtacgac gcctgtgttc ggctcaatgg tgcagaatgg aaagttggcc
     1501 gcttcaatac cggctttggt cagcgcgttg aacagggtag atttcccgac gttgggcaaa
     1561 ccgacgatac cgcatttgaa tcccatgatt taaatcacct taatatctta ataatcaacc
     1621 tgttattgct aacagattgc agaaatggaa ataactttgc ctattataca cggcactcgg
     1681 caaaaatgcc gcagacaacg acttattgcg ctttaaaggc gtgcaatcgg ttcgttgctt
     1741 tggtcaagcc atctgtaaac cacatttcag tacaacgcgc cgcttcgtcg atggcttcat
     1801 caattaactt ctgttcacta acaggcggtt tgcctaacac aaaaccgaca actttatttt
     1861 tatcgcccgg atgaccgatt ccgatgcgta aacggtgaaa gttagggtta ttacccaatt
     1921 tactgatgat gtctttcagt ccattgtgac caccatggcc accgcccaat ttaaatttgg
     1981 cgacgccagg aggcagatcc agttcgtcgt gggccaccag aatttcgtcc ggattaatgc
     2041 ggaaaaaact ggccatcgcc gcaacggctt tgccgctgag attcataaat gtagtcggga
     2101 ctaacaggcg gacatcttcg cctccaagag tgactcgcga agtataacca aagaatttag
     2161 cctcttcgcg cagcggagcg cgcaaacgct ctgccagtaa gtcaacgaac caggcaccag
     2221 cattatgtcg cgttgcggcg tattcagcac cggggttcgc caggccgaca atcaatttaa
     2281 tcgtcacgtt tttttgtcct gagtgtgtac ataactggcg cgtagtttac tggttgcggc
     2341 cccgcttgac aaaaaactgc gtatcaaatg cagataacgt aataattgca tgagtggact
     2401 attagaaagt caaggtgttc aggcgtttat ttgtaaagtt ttgttgaaat aagggttgta
     2461 attgtgatca cgcccgcaca taacccacag ggtgttgtct atactttaca cataaggaag
     2521 aggggtattc cctgttacaa cccagaaagt tccggaggtg acatatgaaa cgcaaaaacg
     2581 cttcgttact cggtaacgtg ctcatggggt tgggtctggt ggtaatggtg gtcggcgtgg
     2641 ggtattcaat cctcaaccag ttaccacagt ttaatatgcc ccagtatttc gcacatggtg
     2701 cagtgctaag tattttcgtc ggtgccattc tctggctggc gggtgcccgt gttggcgggc
     2761 atgaacaggt gtgcgaccgt tactggtggg ttcgccacta tgacaaacgt tgccgccgta
     2821 gcgataatcg ccgtcatagc taacaaataa tgcagtttgc tgaccagtca gtttgcgctg
     2881 actggtcaat ctcgtactta taaatccgcc atcgccgcgc gacgattcgg gaagaacgcc
     2941 aggcgtcccg ggatcggttg aatgccagcg cgagccatag tgcgcagtgg ctggaattcc
     3001 acgttgcaca cgcgcagttc acatccctcg ggcagacgct tcacaaaacg ctggaacgca
     3061 tcaagaccac cagcatcaag taccggaacc gcatcccact tcagaatcac aatccgtttg
     3121 ccttcaagac gtgactccag gtccgtgaac aagccttcag cagcagcaaa aaacagcggg
     3181 ccaataacgc gcagaaccag gacatcgtct ggaacatcta cgactaccgg tgccaggcga
     3241 gtcatacgtg cgatacgacg cataaacagc agcgatgcca gcacgatccc cacgctgatg
     3301 gcaataacca tatcaaacag cacggtcagc gacatgcaca gcagcatgac aatgatgtca
     3361 tctttcggcg catgacgcag caagtcgacc actttgtgcg cttcactcat gttccacgcc
     3421 accatcaaca gcagggcagc catggcggaa agcggcagcc aggagagcag cggtgccagt
     3481 accagcaggg caagaataac cagaatagag tggatcaccg ccgagatagg ggaagttgcc
     3541 ccggcacgga cgttagcggc agaacgcgcg atggcagctg tagcggtaat gccaccaaag
     3601 aacggagcga tgatattccc cagtccctgt ccaaccagtt cgctattcgc cttgtgtttc
     3661 gtcccggtca taccatccag caccacggcg cagagcagag attcgattgc gccgagcatt
     3721 gccattgaga atgccgcagg cagcagtgtg cgaatagaat cccaggttag cgtgaattct
     3781 gaattaggca gatcccacgg cagcaccagt tgcggcagca gttgcggaat accgttaccc
     3841 tgagaaccat cggccaggac gtagtggaat tgcgaaccga tggtagcaac atgtccgccg
     3901 agcaggttaa caatccccat caccgcgcaa ccagccagca aggccggaag gtgaccgggt
     3961 aaacgaatgc ccagacgcgg ccagaaaaca agaataccta gcgtcacaat gccaatggca
     4021 gcatcaccca cattaatggt cggcagcgcc ataaataatg cgccgacttt ttgtagataa
     4081 tgttccggga catgggccat ttgcagaccg agaaaatctt taatctgcat ggtaccgatg
     4141 gtgatcccga tacccgaggt gaaacctaag gtgacggaaa ccggaatata ctcaatcagg
     4201 cgaccaaagc gtgccagacc catcagaatc aaaaaaatcc ccgacagcaa ggtcgcaacc
     4261 agcagtcctg ccagtccaaa ctgttgcgac acgggataga gaattaccac aaatgccgca
     4321 gtcggaccgg aaacgctaaa gcgtgaccca cccgtcagag caatgacaat ccccgcaaca
     4381 gctgcggtat ataaaccgta ctggggtgcc acaccactac caatagccaa cgccatcgcc
     4441 agcgggatag caataatccc gacggttatc ccggcaatca ggtcacgggt aaaccgtgcg
     4501 gcagtatatt tttctttcca gcaagcgtcg atcagagcgc ggaaaggcat cacatgtgag
     4561 gaaaatattt tgttcacaat aatgtttcat ccgtgagcgc atcatctgtc aactaaatgg
     4621 caggtgaagg aggcataggt catacaaatg gatattacag acaaaaaaac ccgccgcagc
     4681 gggtctttga gccgggttcg attagtgttc gaacatggca gagatcgatt cttcgttgct
     4741 gatacgacga atcgcttcgg ccagcatacc tgacagggtc agagtacgca cgttcggcag
     4801 tgatttgatt tcatcgctca gcggaatggt atcgcagaca acgacttcat caattacaga
     4861 gttacgcagg ttgttcgccg cgttgccaga gaagatcggg tgagtcgcgt acgcaaatac
     4921 acgtttagca ccacgttctt tcagagcttc agcagcttta cacagcgtac cgccagtgtc
     4981 gatcatatca tcgaccagta cgcagtcacg acctgcaacg tcaccgatga tatgcatcac
     5041 ctgggaaacg ttcgcacgcg gacgacgttt gtcgatgatt gccatatcgg tatcgttcag
     5101 cagcttagcg atagcgcggg cacgcacaac gccgccgatg tccggagaaa ccacaattgg
     5161 gttatccaga ttcagctgca gcatgtcttc cagcaggatc gggctaccaa atacgttatc
     5221 aaccggaacg tcgaagaaac cctgaatctg ttcagcgtgc agatccactg tcagcacacg
     5281 gtcaacaccg acgctggaga ggaagtctgc aaccactttc gcagtgattg gtacacgagc
     5341 ggaacggacg cgacggtcct ggcgcgcata gccaaagtag gggataacag cggtgatacg
     5401 acctgcggaa gcacgacgca gggcatcaac cataacgact aattccatca ggttgtcgtt
     5461 agtaggggca caagtggact ggatgatgaa aatatcacca ccgcgtacat tttcattaat
     5521 ttgtacgctg acttcgccat cgctaaagcg acctacagcg gcgtcgccga gtgaagtgta
     5581 caggcggttg gcaatacgtt gtgctagttc cggggtggcg ttaccagcaa aaagcttcat
     5641 atcaggcacg agaagaacct caggcatgcg tccattggtg gaaagaatct gccgaaaact
     5701 gtgcgggcca ggcatgatcc tttccaggcg gtgtattaaa gagcgcgatg caacgtctgg
     5761 aacaaggtga cgttgtcacc gaaactcagc ttgcccggct taaagcatgg ctctgtgcaa
     5821 tggggaaaga ttaacgcctt tcgccacaaa gccattgagc cattccgggg cttgctctag
     5881 cacctggcgg gcttcagact ctgtatcaaa ttcagcaaag acacaggccc ctgtcccagt
     5941 caggcgcgac ggggcgtatt ctaacagcca ggaaagcacc gcatcaacct cgcgaaaacg
     6001 ttttcttgcg ataacctcgc aatcattgct gaattcacat tttagcaacg tttctattga
     6061 cctttttggc gtattgcgcg ggagttcagg atctttaaaa atcaccggag tcggaatact
     6121 tacaccaggg tgcgccacca gataccactt ctctggcgga tccaccggcg ttagtatttc
     6181 accaacgcct tcggcaaacg cggcatgccc ccgaacaaag acaggaacat ctgcgcccag
     6241 cgtcagcccc atttccgcca gctcatccat gcttagcccg cattgccaga gatgatttaa
     6301 tgccaccagg accgtcgcgg cattggatga accaccgccg agaccgccgc ccatcggcaa
     6361 acgcttgtca atgctgatat tcgcaccgct tcccgtcgga agacgcccgc tgtctgccgc
     6421 agttttcatc aacaatcgcg ctgcgcgaac gatcaggtta tcttcatgtt ccacgccttc
     6481 aacgggcgtt aacagacgaa tatccccatc gtcacgaagc tcaatgctga tggtgtcgcc
     6541 gtaatcaaga aactgaaaca gcgtttgcag cgtgtggtaa ccatccgcac gctgaccggt
     6601 aatgtataaa aacagattaa gttttgccgg agagggccac tgtgtccgca ttatttcact
     6661 atccagttat ccatttttaa cttgatgcgt tgaccaccgt cggtgagttc catattggct
     6721 ggcatcgcag gttgcgtttt ggtgtcataa ccaccataaa caaccttcca gtttttgcca
     6781 ttctggctgt aggtaatttc gctcaggcgg tactggtcgt ccagtttgta gtcggttgca
     6841 tcacccggta aacctaaaat ccactggcgc aagctgttga gcggaattgg cattccggtc
     6901 aatttgccaa tcatctcttc ggcgtcatcg gcggtataac gctgaccttt attgtcgact
     6961 aactgcacgt tacccggttg agcattcagc tccagttccg tgctgcccaa tgggttagtg
     7021 agcagcagac ggtagcgatc ctggccggtt tgctgccaga aaaagcgggc gtacactttt
     7081 tgttggtcag aaatataagc gaacgcgccg cgagtctgat actgattaag attgcgcacg
     7141 tcttgctgat gctgacgcca ttgtggcgaa tccgggcttt tgccaggacc tttgggcgtg
     7201 gtaacggaac aggcagtgag cacaagagca gccagcggta gcaggcggat aagacgaaaa
     7261 tcgggcaggg gcatagtgat gacaagtcct tgagatacgt tgcagttata acccttaatg
     7321 ctagcgttac cgtccgctat cgtctatgtt caagttgtct taattgccag aatctaacgg
     7381 ctttcggcaa ttactccaaa agggggcgct ctcttttatt gatcttacgc atcctgtatg
     7441 atgcaagcag actaacccta tcaacgttgg tattatttcc cgcagacatg acccttttag
     7501 cactcggtat caaccataaa acggcacctg tatcgctgcg agaacgtgta tcgttttcgc
     7561 cggataagct cgatcaggcg cttgacagcc tgcttgcgca gccgatggtg cagggcggcg
     7621 tggtgctgtc gacgtgcaac cgcacggaac tttatcttag cgttgaagag caggataacc
     7681 tgcaagaggc gttaatccgc tggctttgcg attatcacaa tcttaatgaa gaagatctgc
     7741 gtaaaagcct ctactggcat caggataacg acgcggttag ccatttaatg cgtgttgcca
     7801 gcggcctgga ttcactggtt cttggggagc cgcagatcct cggtcaggtt aaaaaagcgt
     7861 ttgccgattc gcaaaaaggt catatgaagg ccagcgaact ggaacgcatg ttccagaaat
     7921 ctttctctgt agcgaaacgc gttcgcactg aaacagatat cggtgccagt gctgtgtctg
     7981 tcgcttttgc ggcttgtacg ctggcgcggc agatctttga atcgctctct acggtcacag
     8041 tgttgctggt aggcgcgggc gaaaccatcg agctggtagc gcgtcatctg cgcgaacata
     8101 aagtacagaa gatgattatc gccaaccgca ctcgcgaacg tgcccaaatt ctggcagatg
     8161 aagttggcgc ggaagtgatt gccctgagtg agatcgacga acgtctgcgc gaagccgata
     8221 tcatcatcag ttccaccgcc agcccgttac cgattatcgg gaaaggcatg gtggagcgcg
     8281 cattaaaaag tcgtcgtaac caaccaatgc tgttggtgga tattgccgtt ccgcgcgatg
     8341 ttgagccgga agttggcaaa ctggcgaatg cttatcttta tagtgtggac gatctgcaaa
     8401 gcataatttc gcacaacctg gcgcagcgta aagccgcagc ggttgaggcg gaaactattg
     8461 tcgctcagga aaccagcgaa tttatggctt ggctgcgagc acaaagcgcc agcgaaacca
     8521 ttcgcgagta tcgcagccag gcagagcacg ttcgcgatga gttaaccgcc aaagcgttag
     8581 cggcccttga gcagggcggc gacgcgcaag ccattatgca ggatctggca tggaaactga
     8641 ctaaccgctt gatccatgcg ccaacgaaat cacttcaaca ggccgcccgt gacggggata
     8701 acgaacgcct gaatattctg cgcgacagcc tcgggctgga gtagcagtac atcattttct
     8761 ttttttacag ggtgcattta cgcctatgaa gccttctatc gttgccaaac tggaagccct
     8821 gcatgaacgc catgaagaag ttcaggcgtt gctgggtgac gcgcaaacta tcgccgacca
     8881 ggaacgtttt cgcgcattat cacgcgaata tgcgcagtta agtgatgttt cgcgctgttt
     8941 taccgactgg caacaggttc aggaagatat cgaaaccgca cagatgatgc tcgatgatcc
     9001 tgaaatgcgt gagatggcgc aggatgaact gcgcgaagct aaagaaaaaa gcgagcaact
     9061 ggaacagcaa ttacaggttc tgttactgcc aaaagatcct gatgacgaac gtaacgcctt
     9121 cctcgaagtc cgagccggaa ccggcggcga cgaagcggcg ctgttcgcag gcgatctgtt
     9181 ccgtatgtac agccgttacg ccgaagcccg ccgctggcgg gtagaaatca tgagcgccag
     9241 cgagggtgaa catggtggtt ataaagagat catcgccaaa attagcggtg atggtgtgta
     9301 tggtcgtctg aaatttgaat ctggcggtca tcgcgtgcag cgtgttcctg ctacggaatc
     9361 gcagggtcgt attcatactt ctgcttgtac cgttgcggta atgccagaac tgcctgacgc
     9421 agaactgccg gacatcaacc cagcagattt acgcattgat actttccgct cgtcaggggc
     9481 gggtggtcag cacgttaaca ccaccgattc ggcaattcgt attactcact tgccgaccgg
     9541 gattgttgtt gaatgtcagg atgaacgttc acaacataaa aacaaagcga aggcgctttc
     9601 agtgctcggt gctcgcatcc acgctgctga aatggcaaaa cgccaacagg ccgaagcgtc
     9661 tacccgtcgt aacctgctgg ggagtggcga tcgcagcgac cgtaaccgta cttacaattt
     9721 cccgcagggg cgcgttaccg atcaccgcat caacctgacg ctctaccgcc tggatgaagt
     9781 gatggaaggt aagctggata tgctgattga accgattatc caggaacatc aggccgacca
     9841 actggcggcg ttgtccgagc aggaataatg gaatatcaac actggttacg tgaagcaata
     9901 agccaacttc aggcgagcga aagcccgcgg cgtgatgctg aaatcctgct ggagcatgtt
     9961 accggcagag ggcgtacttt tattctcgcc tttggtgaaa cgcagctgac tgacgaacaa
    10021 tgtcagcaac ttgatgcgct actgacacgt cgtcgcgatg gtgaacccat tgctcattta
    10081 accggggtgc gagaattctg gtcgttgccg ttatttgttt cgccagcgac cttaattccg
    10141 cgcccggata cggagtgtct ggtggagcag gcactggcgc ggttgcctga acaaccttgc
    10201 cgtattcttg atctcgggac gggtaccggg gcgattgcgc ttgcgctggc tagcgagcgc
    10261 ccggactgcg aaattatcgc tgtagatcgt atgcctgatg ctgtctccct ggcacaacgt
    10321 aatgcccagc atctggcgat caaaaatatc cacattctgc aaagcgactg gtttagcgcg
    10381 ctagccgggc agcagtttgc gatgattgtc agcaatccgc cgtatattga cgagcaggac
    10441 ccacatcttc aacaaggcga tgtccgcttt gagccgctca ctgcgctggt tgcggcagac
    10501 agtggaatgg cagacatcgt gcatatcatc gaacagtcgc gtaacgcgct ggtatccggc
    10561 ggctttctgc ttctggaaca tggctggcag cagggcgaag cggtgcgaca agcatttatc
    10621 ctcgcggggt atcatgacgt cgaaacctgc cgtgactatg gtgataacga gcgcgtaacg
    10681 ctcggccgct attatcaatg acaagttttt ctacactgct tagtgttcat cttattagtc
    10741 tcgcgctttc tgttgggcta ttaaccttac gtttctggct acgttatcag aagcatccac
    10801 aggcatttgc tcgctggacg cgcattgtgc cgccggttgt cgatacggtg ttattgttaa
    10861 gcggcattgc gttgatggct aaagcgcaca tcctgccatt ttccgggcag gcacagtggc
    10921 tgactgaaaa gctgtttgga gttatcattt atatcgtttt gggttttatt gcactcgatt
    10981 atcgtcgtat gcacagtcag caggcgcgca ttattgcctt cccgctggcg ttggtggtgc
    11041 tgtacatcat cattaaactc gccaccacaa aagtaccgtt actggggtaa gtcatgagat
    11101 cgttagctga tttcgaattt aataaagcgc cattgtgcga aggcatgatc ctggcttgcg
    11161 aagcaatccg ccgcgatttt ccctcgcaag atgtttacga cgaactggag cgtctcgtta
    11221 gtctggcgaa ggaagaaatc agccagcttc tgcctttaga agagcagctg gaaaaactga
    11281 tcgcgctgtt ttacggcgac tggggattta aagcctcacg cggcgtttat cgtctttccg
    11341 atgcattatg gctggaccag gtgttaaaga atcgacaggg cagtgcggta tcattaggtg
    11401 cggttttatt atgggtcgcg aatcgtctcg atttgccgct gctgccggtg attttcccta
    11461 cgcagctgat attgcgcatt gaatgtccgg atggcgaaat ttggctgatt aatcctttta
    11521 acggtgaatc gttaagcgaa catatgctgg acgtatggtt aaagggaaat atcagcccgt
    11581 cggcggaact gttttatgaa gaccttgatg aagctgataa cattgaggta atccgcaaat
    11641 tgctggatac actcaaagcc tcgttgatgg aagaaaatca gatggagctg gcgttacgca
    11701 ccagcgaagc tttattacaa ttcaaccctg aagatcccta tgaaattcgc gatcgcgggt
    11761 tgatttatgc gcaactggat tgcgaacacg ttgcgttgaa cgatttaagt tatttcgttg
    11821 aacagtgtcc ggaagacccg atcagcgaaa tgatccgtgc gcaaataaat aacatcgcgc
    11881 ataaacatat tgtgctgcat taattaatcg acattttact caagattaag gcgatcctat
    11941 gaaacaaaaa gtggttagca ttggcgacat caacgtagca aatgacctgc cgttcgtact
    12001 gtttggcggt atgaacgtgc tggaatctcg cgatctggcg atgcgcattt gcgagcacta
    12061 cgtaactgtg acccagaaac tgggtatccc ttacgtgttc aaagcctctt ttgacaaagc
    12121 caaccgctcc tccatccact cttatcgtgg accgggcctg gaagaaggga tgaaaatctt
    12181 ccaggagttg aagcagactt ttggcgtgaa aattatcacc gacgttcacg aaccaagtca
    12241 ggcacagccc gttgctgatg tcgtggatgt gattcagttg ccggcgtttc ttgctcgcca
    12301 gactgacctg gttgaagcca tggcgaaaac cggtgcggta attaacgtca agaaaccaca
    12361 gtttgtcagc ccgggacaga tgggtaatat cgttgataaa ttcaaagaag gcggcaacga
    12421 aaaagtgatt ctttgcgatc gtggtgctaa cttcggctat gacaacctgg ttgtcgatat
    12481 gctgggcttc agcattatga agaaagtgtc tggtaactcg ccggtgattt tcgacgtgac
    12541 ccacgcactg caatgccgcg atccgtttgg cgcagcttcc ggtggtcgtc gtgctcaggt
    12601 ggctgagctg gcacgagccg gtatggcggt aggtctggcg gggctgttta ttgaagcgca
    12661 tccggatccg gaacatgcga aatgtgatgg tccatccgcg ctgccgctgg ctaaactgga
    12721 accgttcctc aagcagatga aagcgattga tgatctggtg aaaggtttcg aagaactgga
    12781 taccagcaag taatcttttt tgcttgaaaa ataaagtctt agcgttctgc gttaagactt
    12841 ttttcatggg tgccagatac aaaaaaggcc gcaggctgtt acccctgcgg ccggtttcgg
    12901 gcgcatattg ccatcacggc agcctgacgc ccgttttcac cttacttccg gttacgccac
    12961 cagccgacaa
//
LOCUS       DAPGUL010000129        12798 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.132, whole genome shotgun sequence.
ACCESSION   DAPGUL010000129 DAPGUL010000000
VERSION     DAPGUL010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12798
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.132"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..1006)
                     /gene="araG"
                     /locus_tag="RHX21_003898"
     CDS             complement(<1..1006)
                     /gene="araG"
                     /locus_tag="RHX21_003898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter ATP binding protein
                     AraG"
                     /protein_id="HDV1989022.1"
                     /translation="MQQSTPYLSFRGIGKTFPGVKALTDISFDCYAGQVHALMGENGA
                     GKSTLLKILSGNYAPTTGSVVINGQEMSFSDTTAALNAGVAIIYQELHLVPEMTVAEN
                     IYLGQLPHKGGIVNRSLLNYEAGLQLKHLGMDIDPDTPLKYLSIGQWQMVEIAKALAR
                     NAKIIAFDEPTSSLSAREIDNLFRVIRELRKEGRVILYVSHRMEEIFALSDAITVFKD
                     GRYVKTFTDMQQVDHDALVQAMVGRDIGDIYGWQPRSYGEERLRLDAVKAPGVRTPIS
                     LAVRSGEIVGLFGLVGAGRSELMKGMFGGTQITAGQVYIDQQPIDIRKPSHAIAAGMM
                     L"
     gene            complement(1076..2065)
                     /gene="araF"
                     /locus_tag="RHX21_003899"
     CDS             complement(1076..2065)
                     /gene="araF"
                     /locus_tag="RHX21_003899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter substrate-binding
                     protein AraF"
                     /protein_id="HDV1989023.1"
                     /translation="MHKFTKALAAIGLAAVMSQSAMAENLKLGFLVKQPEEPWFQTEW
                     KFADKAGKDLGFEVIKIAVPDGEKTLNAIDSLAASGAKGFVICTPDPKLGSAIVAKAR
                     GYDMKVIAVDDQFVNAKGKPMDTVPLVMMAATKIGERQGQELYKEMQKRGWDVKESAV
                     MAITANELDTARRRTTGSMDALKAAGFPEKQIYQVPTKSNDIPGAFDAANSMLVQHPE
                     VKHWLIVGMNDSTVLGGVRATEGQGFKAADIIGIGINGVDAVSELSKAQATGFYGSLL
                     PSPDVHGYKSSEMLYNWVAKDVEPPKFTEVTDVVLITRDNFKEELEKKGLGGK"
     gene            2862..3365
                     /locus_tag="RHX21_003900"
     CDS             2862..3365
                     /locus_tag="RHX21_003900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-heme ferritin-like protein"
                     /protein_id="HDV1989024.1"
                     /translation="MATAGMLLKLNSQMNREFYASNLYLHLSNWCSEQSLNGTATFLR
                     AQAQSNVTQMMRMFNFMKSVGATPIVKAIDVPGEKLNSLEELFQKTMEEYEQRSSTLA
                     QLADEAKELNDDSTVNFLRDLEKEQQHDGLLLQTILDEVRSAKLAGMCPVQTDQHVLN
                     VVSHQLH"
     gene            complement(3444..3695)
                     /locus_tag="RHX21_003901"
     CDS             complement(3444..3695)
                     /locus_tag="RHX21_003901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416416.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2766 domain-containing protein"
                     /protein_id="HDV1989025.1"
                     /translation="MSQPLNADQELVSDVVACQLVIKQILDVLDVIAPVEVREKMSSQ
                     LKNIDFTNHPAAADPVTMRAIQKAIALIELKFTPQGESH"
     gene            complement(3810..3896)
                     /gene="azuC"
                     /locus_tag="RHX21_003902"
     CDS             complement(3810..3896)
                     /gene="azuC"
                     /locus_tag="RHX21_003902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein AzuC"
                     /protein_id="HDV1989026.1"
                     /translation="MKLRKILKSMFNNYCKTFKDVPPGNMFR"
     gene            4159..4482
                     /locus_tag="RHX21_003903"
     CDS             4159..4482
                     /locus_tag="RHX21_003903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YecR-like lipofamily protein"
                     /protein_id="HDV1989027.1"
                     /translation="MRLLILTLSLITLAGCTVTRQAHVSEVDAATGIVRLVYDQAFLQ
                     HARTDRYVSRGIADRACQQEGYTHAIPFGQPVGNCSLFAGSLCLNTEFTLSYQCHHSA
                     FPVFL"
     gene            4654..5151
                     /gene="ftnA"
                     /locus_tag="RHX21_003904"
     CDS             4654..5151
                     /gene="ftnA"
                     /locus_tag="RHX21_003904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-heme ferritin"
                     /protein_id="HDV1989028.1"
                     /translation="MLKPEMIEKLNEQMNLELYSSLLYQQMSAWCSYHTFEGAAAFLR
                     RHAQEEMTHMQRLFDYLTDTGNLPRINTVESPFAEYSSLDELFQETYKHEQLITQKIN
                     ELAHAAMTNQDYPTFNFLQWYVSEQHEEEKLFKSIIDKLSLAGKSGEGLYFIDKELST
                     LDTQN"
     gene            complement(5189..5428)
                     /locus_tag="RHX21_003905"
     CDS             complement(5189..5428)
                     /locus_tag="RHX21_003905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YecH family protein"
                     /protein_id="HDV1989029.1"
                     /translation="MDSIHGHEVLNMMIESGEQYTHASLEAAIKARFGEQARFHTCSA
                     EGMTAGELVAFLAAKGKFIPSEEGFSTDQSKICRH"
     gene            5618..6829
                     /gene="tyrP"
                     /locus_tag="RHX21_003906"
     CDS             5618..6829
                     /gene="tyrP"
                     /locus_tag="RHX21_003906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine transporter TyrP"
                     /protein_id="HDV1989030.1"
                     /translation="MKNRTLGSVFIVAGTTIGAGMLAMPLAAAGVGFSVTLILLIGLW
                     ALMCYTALLLLEVYQHVPADTGLGTLAKRYLGRYGQWLTGFSMMFLMYALTAAYISGA
                     GELLASSISDWTGISMSATAGVLLFTFVAGGVVCVGTSLVDLFNRFLFSAKIIFLVVM
                     LVLLLPHIHKVNLLTLPLQQGLALSAIPVIFTSFGFHGSVPSIVSYMDGNVRKLRWVF
                     ITGSAIPLVAYIFWQVATLGSIDSTTFMGLLANHAGLNGLLQALREMVASPHVELAVH
                     LFADLALATSFLGVALGLFDYLADLFQRSNTVGGRLQTGAITFLPPLAFALFYPRGFV
                     MALGYAGVALAVLALIIPSLLTWQSRKHNPQAGYRVKGGRPALVVVFLCGIAVIGVQF
                     LIAAGLLPEVG"
     gene            complement(6891..7556)
                     /gene="yecA"
                     /locus_tag="RHX21_003907"
     CDS             complement(6891..7556)
                     /gene="yecA"
                     /locus_tag="RHX21_003907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0149 family protein YecA"
                     /protein_id="HDV1989031.1"
                     /translation="MKTGPLNESELEWLDDILTKYNTDHAILDVAELDGLLTAVLSSP
                     QEIEPEQWLVAVWGGADYVPRWASEKEMTRFMNLAFQHMADTAERLNEFPEQFEPLFG
                     LREVDGSELTIVEEWCFGYMRGVALSDWSTLPDSLKPALEAIALHGTEENFERVEKMS
                     PEAFEESVDAIRLAALDLHAYWMAHPQEKAVQQPIKAEEKPGRNDPCPCGSGKKFKQC
                     CLH"
     gene            complement(7752..7838)
                     /locus_tag="RHX21_003908"
     tRNA            complement(7752..7838)
                     /locus_tag="RHX21_003908"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7802..7804),aa:Leu,seq:taa)
     gene            complement(7851..7924)
                     /locus_tag="RHX21_003909"
     tRNA            complement(7851..7924)
                     /locus_tag="RHX21_003909"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7890..7892),aa:Cys,seq:gca)
     gene            complement(7978..8053)
                     /locus_tag="RHX21_003910"
     tRNA            complement(7978..8053)
                     /locus_tag="RHX21_003910"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(8018..8020),aa:Gly,seq:gcc)
     gene            complement(8205..8753)
                     /gene="pgsA"
                     /locus_tag="RHX21_003911"
     CDS             complement(8205..8753)
                     /gene="pgsA"
                     /locus_tag="RHX21_003911"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HDV1989032.1"
                     /translation="MQFNIPTLLTLFRVILIPFFVLVFYLPVTWSPFAAALIFCVAAV
                     TDWFDGFLARRWNQSTRFGAFLDPVADKVLVAIAMVLVTEHYHSWWVTLPAATMIARE
                     IIISALREWMAELGKRSSVAVSWIGKVKTTAQMVALAWLLWRPNIWVEYAGIALFFVA
                     AVLTLWSMLQYLSAARADLLDQ"
     gene            complement(8810..10642)
                     /gene="uvrC"
                     /locus_tag="RHX21_003912"
     CDS             complement(8810..10642)
                     /gene="uvrC"
                     /locus_tag="RHX21_003912"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310678.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HDV1989033.1"
                     /translation="MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLS
                     SYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSY
                     PFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
                     NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETAS
                     QNLEFEEAARIRDQIQAVRRVTEKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKV
                     LGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLS
                     ELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEV
                     KRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRY
                     GKAIDDSKIPDVILIDGGKGQLAQAKNVFAELDVSWDKNHPLLLGVAKGVDRKAGLET
                     LFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLETIEGVGP
                     KRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH"
     gene            complement(10639..11295)
                     /gene="uvrY"
                     /locus_tag="RHX21_003913"
     CDS             complement(10639..11295)
                     /gene="uvrY"
                     /locus_tag="RHX21_003913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrY/SirA/GacA family response regulator
                     transcription factor"
                     /protein_id="HDV1989034.1"
                     /translation="MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCR
                     ANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIMLTVHTENPLPAKVMQAGAAGYL
                     SKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
                     ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ
                     "
     gene            11591..11767
                     /locus_tag="RHX21_003914"
     CDS             11591..11767
                     /locus_tag="RHX21_003914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989035.1"
                     /translation="MIKIFIGHYINAFNSTVDDTLKKQPLLFLAKLMVYSAALTFFTA
                     NFHCNMTRKINEYA"
     gene            11754..11978
                     /locus_tag="RHX21_003915"
     CDS             11754..11978
                     /locus_tag="RHX21_003915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2594 family protein"
                     /protein_id="HDV1989036.1"
                     /translation="MSTPDFSTAENNQELANEVSCLKAMLTLMLQAMGQADAGRVMLK
                     MEKQLALIEDETQAAVFSKTVKQIKQAYRQ"
     gene            complement(12046..12768)
                     /gene="sdiA"
                     /locus_tag="RHX21_003916"
     CDS             complement(12046..12768)
                     /gene="sdiA"
                     /locus_tag="RHX21_003916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SdiA"
                     /protein_id="HDV1989037.1"
                     /translation="MQDTDFFSWRRTMLLRFQRMEAAEEVYHEIEFQAQQLEYDYYSL
                     CVRHPVPFTRPKVAFYTNYPEAWVSYYQAKNFLAIDPVLNPENFSQGHLMWNDDLFSE
                     AQPLWEAARAHGLRRGVTQYLMLPNRALGFLSFSRSSAREIPILSDELQLKMQLLVRE
                     SLMALMRLNDEIVMTPEMNFSKREKEILKWTAEGKTSAEIAMILSISENTVNFHQKNM
                     QKKINAPNKTQVACYAAATGLI"
BASE COUNT         3227 a         3229 c         2933 g         3409 t
ORIGIN      
        1 agagcatcat gcctgcggca atggcgtggc tcggtttacg aatatcgatc ggctgttggt
       61 cgatataaac ctgaccggcg gtgatttgcg tcccgccaaa catgcctttc attaattcgc
      121 tacgccccgc ccctaccaga ccaaacagcc caacaatttc accactgcga accgccagac
      181 ttattggcgt acgcacgcct ggtgctttca cagcatcaag acgtaggcgc tcctcgccat
      241 aactacgcgg ttgccagccg tagatatcgc caatgtcgcg cccgaccatc gcctgcacca
      301 gcgcgtcgtg gtcaacctgc tgcatatcgg taaaggtttt gacataacgt ccatctttaa
      361 agacagtaat ggcatcgctg agggcaaata tttcttccat acggtgagaa acgtataaga
      421 ttacccgccc ctcttttcgc agttcacgaa taacgcggaa aagattgtcg atttcacggg
      481 cagaaaggga gctggttggc tcatcaaagg cgataatttt ggcgttacgc gccagcgctt
      541 tggcgatttc aaccatctgc cactgaccaa tggagagata tttcagcggc gtgtccgggt
      601 caatatccat accaagatgt ttaagttgta aacccgcctc ataattcagc aatgagcgat
      661 tcacaatgcc gcctttatgc ggcagctggc cgagatagat gttttccgcg acggtcattt
      721 ccggcacgag atgcagttcc tggtaaataa tcgccacgcc cgcgttaagt gctgcggtcg
      781 tgtcggaaaa ggacatttcc tgcccattaa tcactacaga acccgtggtt ggcgcatagt
      841 tgccgctgag gatttttaag agagttgatt ttcctgcgcc attttcaccc atcaacgcat
      901 gaacctgacc ggcatagcag tcaaaactaa tatccgtcag cgccttaacg ccgggaaacg
      961 ttttaccgat gccgcgaaat gagagatacg gggtagactg ttgcataacg tctccgtgaa
     1021 tcactggtcg ttcacacccc ctctgcatca tgcagagggg aatttttccg gcaaattact
     1081 taccgcctaa accttttttc tccagttctt ctttaaagtt gtcacgcgtg atcagtacca
     1141 cgtcggtaac ttcggtaaat tttggcggtt caacgtcttt tgctacccag ttgtaaagca
     1201 tttcgctgga tttatagcca tgtacgtccg ggcttggcag cagggaaccg tagaagccgg
     1261 ttgcctgtgc tttagacagt tcgctcaccg catccacacc gttaatgcca atgccgatga
     1321 tatcggccgc tttaaagccc tgaccttccg tcgcgcgtac gccgcccagc acggtgctgt
     1381 cgttcatacc gacgatcagc caatgtttaa cttccggatg ttgaaccagc attgagttgg
     1441 cagcgtcaaa tgcccccggg atgtcgttag atttggtagg tacctgataa atttgttttt
     1501 ccgggaatcc ggccgctttc agcgcatcca tagatcccgt agtacggcgg cgggcggtat
     1561 ccagttcgtt ggcggtaatc gccatcaccg cgctttcttt gacatcccag ccacgtttct
     1621 gcatctcttt atacagttcc tggccctgac gttcgccaat tttagtcgcc gccatcatca
     1681 ccagcggaac ggtatccatt ggcttacctt tggcgttaac aaactggtca tccacggcaa
     1741 tgactttcat atcgtagcca cgcgctttcg cgacgatggc agagccgagt ttggggtccg
     1801 gagtacaaat aacgaaacct tttgcgccac tggcagccag gctgtcgatc gcgttcaatg
     1861 ttttttcgcc atccggcacg gcaatcttaa taacctcaaa ccctaaatcc ttcccggctt
     1921 tatcggcaaa cttccattcg gtctggaacc acggctcttc cggttgcttc accagaaaac
     1981 cgagcttcag gttctccgcc atagcggatt gtgacataac ggctgccaga ccaatggctg
     2041 ccagggcttt agtaaatttg tgcatggttc tctccagctt tagtgtcgtt ttgtgtaggg
     2101 caaaaacgaa tgacattcgt taaattaatc ggaaaacaaa gcattacctt ttaactaaaa
     2161 gataagtgac tgtgttgaca tagttttagc gagaaattaa ttctccatag gagagcaata
     2221 tcacatcgca gaattacagt gagaacgtgc ataaatttag cgggaaaaga cataagggaa
     2281 agccaatttg tcagacaaat tgtcgaatgc acagcagatt aatccataag attagcctgg
     2341 aaatccttgt tgtctttggt acccatgcgg gatgtcttct ttttaaccag tcaataggcc
     2401 gcattacctg gcgttgagtt tttgaaatgg tgtaataacc gcaactcaaa gatgtggaaa
     2461 atgcacgtca ttcatttcgt cattaattat cactgtgctc attaattaac agaacacgta
     2521 taatgagagc catctcgcaa aaatgaaaaa acgttttata aaatcatcac ttcatcatga
     2581 attcaaattc attgattaat atcaacaaga tacaaaaagc actatcatta aaattcattg
     2641 cagttacatt gatttcatca atgaaatgta aaaatatata aacttgatga tttaagcatt
     2701 ttcttatacc cgttcagacg ttattcttat ttcagatcat cgtcagaatt gactccacga
     2761 tcacatttcg gaccggcaga aaggaattat tctgcaaaca gtaattatgg tgttttgatt
     2821 tatcttgcac ctctccactt ctggatataa ggatattagg tatggcaacc gctggaatgc
     2881 ttctcaaact caactctcaa atgaaccgcg agttttacgc atccaatctc taccttcacc
     2941 tgagtaactg gtgttctgaa cagagtctga acggcaccgc cactttcctt cgcgcccagg
     3001 cacagagtaa tgtgacccaa atgatgcgca tgtttaactt tatgaagagt gtcggcgcta
     3061 cccccatcgt taaagccatt gatgttcccg gtgaaaaact gaactctctg gaagaactgt
     3121 tccaaaaaac gatggaagaa tacgagcaac gttctagtac gttggcacag ttagccgatg
     3181 aagcgaaaga actgaatgat gattcaaccg tcaatttcct gcgcgatctg gaaaaagaac
     3241 agcagcatga tggtctgttg ctgcaaacca ttcttgatga agtgcgcagt gcgaaacttg
     3301 cgggtatgtg ccctgtgcag accgaccaac atgttctgaa tgtcgtgtca caccagctgc
     3361 attgatcatc atcggcgcta atgcattgcg ccgatgaagg ttttgagaaa ccgctgcctc
     3421 atctgtttga agcagcggtt tttttaatgg gattcaccct gtggggtaaa cttgagttca
     3481 ataagcgcga tggctttttg gattgcccgc atggtgaccg ggtctgcggc ggcgggatgg
     3541 ttagtaaagt cgatattctt cagctgactg gacatttttt cacgaacttc aacgggcgcg
     3601 attacatcga gaacatccag aatttgtttg ataaccaact ggcaagcaac cacatcagaa
     3661 accagttcct gatcggcatt cagcggctgg gacatcgtaa actcctgata gcattttgaa
     3721 agccgttata gtagcggctt cacatcttca gcgatagtca catccaccgt catcaggaca
     3781 caaaaaaacc tgccggagca ggttttttgt tatcggaaca tattgcctgg cggtacgtct
     3841 ttgaacgtct tgcaatagtt attgaacata cttttcagta ttttgcgcag tttcatcgcg
     3901 gcactccgac catttgttat acaggtgtta ttgtctttgc acttataata tgacaaccat
     3961 cacaaaaatc aatctttatg tgatgtgaat cacataaata cccctttaat gttataaaaa
     4021 tgataatcaa aaagcagcta ccccatttct gacacctaca gatggcaaga aatagcgcct
     4081 gccaggcgtc ttttccggcc attgtcgcag cgctgtaacg cgtaaaatag tgctttcttt
     4141 tactcttctg gctggaccat gagacttctg attctgactc tttcattaat aacgctggcg
     4201 gggtgtacgg ttactcgcca ggcccatgtg agcgaagttg acgcggcaac aggtattgta
     4261 cggttggttt atgaccaggc ttttttgcag catgcccgta ccgatcgtta tgtcagtcgc
     4321 gggatcgccg atcgcgcatg ccagcaggaa ggctataccc acgctatccc ctttggtcag
     4381 ccagtaggca actgtagcct ttttgcgggt tccttatgtt taaatacgga attcactttg
     4441 tcatatcagt gccatcattc cgccttccct gtctttctct aaatgtttta atcagcgagg
     4501 gggatcttcg ctgattaaat aaatagcggt aatgcgtttt attcccattc gtatttttaa
     4561 taaatgaagt tcatatttta ccttttgcaa ataataaaat aacaaattat agtgacgcca
     4621 cagcaacaaa tataaccttt gtggagcact atcatgctga aaccagaaat gattgaaaaa
     4681 cttaatgagc agatgaacct ggaactgtac tcttcactgc tttatcagca aatgagcgcc
     4741 tggtgcagct atcatacctt cgaaggtgct gccgcgttcc tgcgccgcca cgcccaggaa
     4801 gagatgacac atatgcagcg tctgtttgat tacctgactg ataccggaaa cttaccacgt
     4861 attaataccg ttgaatctcc gtttgctgaa tattcttcac ttgatgaatt attccaggaa
     4921 acctataaac acgaacaatt aatcacgcag aaaattaacg aactggctca tgctgcaatg
     4981 accaatcagg actacccaac atttaatttc ctgcaatggt atgtttctga gcagcatgaa
     5041 gaagagaaac tgttcaaatc gattattgat aaattaagcc tggcaggcaa aagcggcgaa
     5101 ggtctgtatt ttatcgacaa agaactctct accctcgaca cacaaaacta atgctctcag
     5161 gcggcaggtt ttctgccgcc gtttcaaatc agtgacggca aatcttactc tgatcggtcg
     5221 aaaaaccttc ttctgaaggt ataaatttgc cttttgctgc cagaaacgct accagctctc
     5281 ccgcagtcat cccttctgcc gagcaggtgt gaaaacgtgc ctgttcacca aaacgcgctt
     5341 taattgctgc ttccagactg gcatgcgtat attgctcgcc tgattcaatc atcatattta
     5401 acacttcatg accgtgaata gagtccatcg ttcctcctca aaaaaagcct agcgtagcga
     5461 ttgccgctta tgaagacttt gcgccagcgc agaactaaac gcttttattg tacatttata
     5521 tttacactat atgtaacgtc ggtttgacga agcagccgtt atgccttaac ctgcgccgca
     5581 gatatcactc ataaagatcg tcaggacaga agaaagcgtg aaaaacagaa ctctgggaag
     5641 tgtttttatc gtggcgggaa ccacaattgg cgcaggcatg ctggcaatgc cgctggctgc
     5701 ggccggtgtt ggttttagcg ttacgttaat cttgttgatt gggctttggg cgttgatgtg
     5761 ctacacggcg ctattactgc tggaggtgta ccagcatgtt ccggcagata ccggtcttgg
     5821 cacgctggca aaacgctatc tgggacgcta cggtcagtgg ctgacgggct tcagtatgat
     5881 gttcttaatg tatgctctga ctgcggcata catcagcggt gccggtgaat tgttggcctc
     5941 cagcatcagc gactggacag gtatttcaat gtcggcaacc gctggcgtgc tgttgttcac
     6001 ttttgttgcc ggtggcgtgg tttgtgtcgg gacatcgctg gtcgatttgt ttaaccgttt
     6061 tctgttcagc gccaaaatta tttttctggt ggtgatgctg gtattgctgc taccgcatat
     6121 tcacaaagtg aatcttttaa ccctgccgtt gcaacagggg ctggctctgt ccgcaatccc
     6181 ggtgattttt acctcgtttg gttttcacgg tagcgtgccg agtattgtca gctatatgga
     6241 tggcaacgtt cgtaagctac gctgggtgtt tataaccggt agtgcgatcc ccctggtggc
     6301 atatattttc tggcaggtgg caacgcttgg cagcattgat tcaacaacct ttatgggatt
     6361 gctggctaat catgctggat taaacgggct gttacaggcg ttacgcgaaa tggtggcctc
     6421 tccgcatgtt gagctggcag tgcatttatt tgctgattta gccctcgcca cgtcatttct
     6481 cggcgttgcg ttaggcttat ttgattatct ggctgattta tttcagcgtt caaataccgt
     6541 tggtggacgg ttgcaaactg gtgcaattac ctttctgccg ccgttggcgt ttgcactgtt
     6601 ttatccacga ggatttgtga tggcgctggg ttacgccggt gtggcgctgg cggtactggc
     6661 attgattatc ccttcgctgt tgacctggca aagcagaaag cacaatcctc aggcgggtta
     6721 ccgggtgaaa ggtggtcgtc cggcgctggt ggtggtgttt ctctgtggta ttgctgtgat
     6781 tggcgtgcaa tttttgattg cggcagggtt gttaccagaa gtggggtgat cagatagcct
     6841 caaattcctt attgggtgcc agaattaacg ctgacaccca atttgacctc ttaatgcagg
     6901 cagcactgct taaatttctt accactaccg cacgggcaag gatcgttacg ccccggtttc
     6961 tcttctgctt tgatcggttg ctgaacagct ttttcctgcg gatgcgccat ccagtacgca
     7021 tgtagatcaa gcgccgccag tcgaatggca tctacgctct cttcaaacgc ttctggcgac
     7081 atcttctcta cccgctcgaa gttttcctca gtaccgtgca gcgcaatcgc ctccagcgct
     7141 ggttttaacg aatcgggcaa cgttgaccag tcagaaagtg ccacgccccg catatagcca
     7201 aagcaccact cctcaacaat cgtcagctcg ctgccatcga cttctcgcaa gccgaataac
     7261 ggctcaaact gctccgggaa ttcgttcaga cgctctgcgg tatcggccat atgttgaaag
     7321 gccaggttca taaagcgcgt catctctttc tctgacgccc agcgcggcac atagtcagcc
     7381 ccaccccaca cggcaaccag ccactgttcc ggttcaatct cttgcggaga actcaacacc
     7441 gccgtcaata aaccgtccag ctccgccaca tcaaggatgg cgtggtcagt gttgtatttg
     7501 gtcagaatat cgtccagcca ttccaactca ctttcgttta acggtcccgt tttcatacgc
     7561 ttttccttgt ggatctcaac tcgccagcac ctatcttaca tgccggtccg tatcagagat
     7621 actttttgag tggctttgcc ggtgattaaa aattaaggag ggtgtaacga caagttgcag
     7681 gcacaaaaaa accacccgaa ggtggtttca cgacactgct tattgctttg attttattct
     7741 tatctttccc atggtacccg gagcgggact tgaacccgca cagcgcgaac gccgagggat
     7801 tttaaatccc ttgtgtctac cgattccacc atccgggctc gggaagaaag tggaggcgcg
     7861 ttccggagtc gaaccggact agacggattt gcaatccgct acataaccgc tttgttaacg
     7921 cgccaaattc ttcaggcctt tcagccagac atccgctgac gccgacgtct tttaaactgg
     7981 agcgggaaac gagactcgaa ctcgcgaccc cgaccttggc aaggtcgtgc tctaccaact
     8041 gagctattcc cgcattcatc aagcaatcag ttaatcactt gattttatta tcgtctggca
     8101 atcagtgccg ccgttcgatg cgttgcattc tacttacctg gcgcgatgag tcaacgatat
     8161 ttttcaccac ttttgatcgt ttgctgaaaa ttgcgccgaa acgatcactg atcaagcaaa
     8221 tctgcacgcg cagcgctcaa atattgcaac attgaccaca gagtcagtac cgcagccaca
     8281 aagaaaagtg caataccggc gtactcaacc caaatgttcg gacgccacag cagccaggcc
     8341 aacgccacca tctgggcagt ggttttcact ttcccaatcc aggagacagc cacgctactg
     8401 cgtttaccca actccgccat ccattcgcgt agcgcagaaa taataatttc acgggcgatc
     8461 atcgttgccg ccggtaaggt cacccaccag ctgtgataat gctcggttac cagcaccatg
     8521 gcgatagcca cgagaacttt atctgctaca gggtcaagga aagcaccaaa ccgggtactc
     8581 tggttccagc ggcgtgccag aaaaccatcg aaccagtcag ttaccgccgc gacgcagaaa
     8641 atgagcgcgg cggcaaacgg cgaccaggtg acaggcagat aaaagaccaa tacaaagaat
     8701 gggataagga tgacacggaa cagtgtaagc aacgtaggga tattaaattg cataatgacg
     8761 ggtaactatc tgttgtcagt aagattaccc ctatgttgct acagagacat caatgtttca
     8821 acgaccagaa gatcttttct gccagacctt gcgaaatacc cggcactttt gcaatttcct
     8881 cgacgctggc gttacgtaaa ccttgcaaac cgcccatata tttcaacaac atttgccggc
     8941 gttttggccc gacgccttca atggtttcca gggaactggt atttttgacc ttcgcccgtt
     9001 ttttacggtg cccgccaatc gcgtgatcgt gtgattcatc gcgaatatgc tggataacat
     9061 gcagcgcggg agaatctggc ggcaaactga atccctcacc ttccggctca aagaacagcg
     9121 tttccagccc agccttacga tctactcctt tggcaacgcc aagtagcagc ggatgatttt
     9181 tatcccatga gacatccagt tcggcgaaga catttttcgc ctgcgcaagc tggcctttgc
     9241 cgccgtcgat aagtatcaca tccgggatct tactgtcgtc gatggcttta ccataacgcc
     9301 gacgcagcac ctgattcatc gccgcataat catcgcccgg cgtgatgcca gtaatgttat
     9361 agcgccgata ctccgcacgc agcgggccgt tagcatcaaa taccacacag gaggcgacgg
     9421 tttgttcacc catggtatgg ctgatgtcaa agcactccat ccgcttcact tccggcaatt
     9481 tcaacacgct ggcaagcgcg gtcagtcgct ggtgaacggt agattgctgc gaaagtttgc
     9541 tggttaaggc cgtcgccgca ttggtgcgcg cgagtttcag ataacgcgcc cgatcgccgc
     9601 gaggtttggt ttgaacatta atcttgcgtc ccgccagttc tgaaagggaa tcggcgagca
     9661 gcgttttatc gctaagatta aaatcgagca ggatctcacc cggtaaggtg cgcatctggc
     9721 tgccttgtaa atagaactga cctacgaagg tttccaccac ctcgctcagt tccgtaccgc
     9781 ccggcacttt cgggaaatag ctgcggctgc cgagcacttt accctgacga atgaacaata
     9841 cgtggacaca agccatgccc gcatcgaacg ccacaccaat aacgtcaagg tcgtcgccgg
     9901 tattggacac aaactgtttt tcggtgacgc gtcgcaccgc ctgaatttgg tcgcgaatac
     9961 gtgccgcttc ttcaaactcc agattctggc tggcagtttc catacggcta atgagttgcg
    10021 taagcacctg atcatctttg ccagacaaaa acaggcgcac atactcgacc tgctgagcgt
    10081 attcttcttc actcaccagt ccttcaacgc acggccccag acagcgccct atctgatatt
    10141 gcagacacgg acgcgagcga ttgcgataaa cactattttc gcactggcga atggggaata
    10201 tcttttgcag taacgccagt gtttcacgta cggcatagcc attcgggaac gggccgaaat
    10261 attcaccttt ggcatgcttc gcaccacgat gcatcgccag acgcgggtgg gtatcgccac
    10321 tcaggaagat aaaaggataa gatttatcat cgcgtagcaa aacgttgtaa cgcggctgat
    10381 agagtttgat gtagttgtgt tccagcaaca gcgcttcggt ttctgtatga gtaaccgtta
    10441 catcaatttg ctggatctgg gcgaccagcg cttcggtttt gcgcgaagcg aggttgctac
    10501 ggaaatagct ggaaagccgt tttttcaggt ctttcgcttt gccgacatag ataaccgtac
    10561 caccagcatc gtacatgcga taaacgcctg gctggctggt tacggttttt aaaaacgctt
    10621 ttgcgtcaaa ctgatcactc actgacttga taatgtctcc gcattacaca gaccatggcg
    10681 aattgccagg tgagtcagct caacatcgcc atgaatgttt agtttactga acatacgata
    10741 gcggtagctg ttcaccgttt tcggactgag attgagctgt tctgagatct cattgacctt
    10801 ctggcccttg gtgatcatca gcataatctg caattcacgt tcagacaaac tggcaaatgg
    10861 gctttctgtt ttttctggtt cgatctggct taacgccatt tgttgagcga tgtcagaagc
    10921 aatgtaacgc tgccctgaat agacagaacg aatcgcactc acgacttcct gcggagccgc
    10981 gcctttgctg aggtagcccg cagcaccggc ctgcatgact ttcgctggta aagggttttc
    11041 tgtatggacg gtaagcatga tgattttgac atcagctgtg gaacgcgcga ttttacgcgt
    11101 cgcctcaaga ccgccaatgc ccggcatact catgtccatt agcaccacgt caacggcatt
    11161 tgcccgacac cacttaacgg cgtcttcacc gcacgatgcc tcaccgacga cttttatacc
    11221 ctttatatct tccagaatgc gtcgtatccc tgcgcgcacc agttcgtggt catcaacaag
    11281 tagaacgttg atcaaaggaa tatctccaga aatagggata acgctactga tagttagtca
    11341 ttcgtatatt agcggttttt attgcaactt tgaaacgtta aaaatggtgg gtattcgatt
    11401 tttctctcgt ttttgtcaat tcgattgtcc atagttatgg tcacgcccgt caccaacggc
    11461 ttaccggatc gtttcacagt aagccctgcg acgaaatgtg acaaaaatta cctttattca
    11521 gcaaaaatga aaatcagccc gctgaatatg taacattaat taacccgaac aatacgggca
    11581 aaaaacattc atgataaaaa tatttattgg tcattatatt aacgcattta atagcaccgt
    11641 tgacgatacg ctcaaaaaac aaccactgct atttttagca aagcttatgg tatactccgc
    11701 cgccttaaca tttttcaccg caaattttca ttgcaacatg acgaggaaaa taaatgagta
    11761 cgcctgattt ttctactgcc gagaataatc aagaactggc aaatgaagtc tcctgcctga
    11821 aagcgatgct gacgctgatg ctgcaggcga tgggacaagc tgacgcgggc cgcgtgatgt
    11881 taaagatgga aaaacagctt gcgctgatcg aagacgaaac ccaggctgca gtattttcca
    11941 aaacggttaa gcaaattaaa caagcctacc gtcagtaata taaaaccggc tgatagcgtg
    12001 cctttcagcc ggtttttgca tctggcacgc aggacagaaa agagatcaaa ttaagccagt
    12061 agcggccgcg taacaggcaa cctgggtctt atttggtgca ttgatttttt tctgcatgtt
    12121 tttctgatgg aaattgaccg tattctcaga gattgacaaa atcatcgcta tctctgctga
    12181 tgtcttccct tccgccgtcc atttcaaaat ttctttttcg cgcttgctga aattcatctc
    12241 tggcgtcatc actatttcat catttaaacg catcagagcc atcagacttt cgcgcaccag
    12301 taactgcatt tttaattgca gttcatcact aagaatgggt atttcgcgcg cgctgctacg
    12361 ggaaaaggac aaaaagccca gcgcccggtt tggcagcatt aaatactgag tgacaccgcg
    12421 gcgtaaacca tgtgcgcgcg cggcttccca taacggctgt gcttcgctga ataagtcatc
    12481 attccacatt aaatggccct gactaaagtt ttcagggttc agcaccggat caattgcgag
    12541 aaagtttttt gcctgataat aactaaccca cgcctcaggg taattggtgt agaaagccac
    12601 tttaggtcgc gtgaatggta ccgggtggcg aacacataac gaatagtaat cgtactccag
    12661 ctgctgagcc tgaaactcta tttcatggta gacctcttct gcggcctcca tcctctgaaa
    12721 acgcaacagc atcgtgcgac gccagctgaa aaaatccgta tcctgcatag taaaccgcaa
    12781 cgcccctgag agtgagta
//
LOCUS       DAPGUL010000130        12525 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.133, whole genome shotgun sequence.
ACCESSION   DAPGUL010000130 DAPGUL010000000
VERSION     DAPGUL010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12525
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.133"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..815
                     /locus_tag="RHX21_003917"
     CDS             <1..815
                     /locus_tag="RHX21_003917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001060172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF2608 domain-containing protein"
                     /protein_id="HDV1989038.1"
                     /translation="SYAQVKNIVTGEYSAVSKIITEKETLYPSDKILLVFDIDNTLLT
                     SGTRIGGDIWYQWQTDKLPLKPDDSQKVPCLYENTISMLYELSPMQLTEPQLPTMLKQ
                     WQQKHTAFALTSRAPDTLFPTLRELKRNGIDFSSSALRKKEDTLPPFEKGKLKRSWLY
                     SQGVFFSSGQDKGVVLDYMLDKMGNKYDAIVFIDDGQANIHAMTKMFSKDKWSSTDFT
                     IIHYTRVEDELIKQQGAVITTAQAEKMATDWKTLAGSLATLFPDRNKLCPIK"
     gene            complement(860..2752)
                     /gene="parE"
                     /locus_tag="RHX21_003918"
     CDS             complement(860..2752)
                     /gene="parE"
                     /locus_tag="RHX21_003918"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HDV1989039.1"
                     /translation="MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSV
                     DEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHPEEGVPAVELILCRLHAGGKFSN
                     KNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN
                     TGTSVHFWPDETFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDG
                     LNDYLAEAVNGLPTLPEKPFIGNFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQG
                     GTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVLSVKMQDPQFAGQTK
                     ERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQRRMRAAKKVVRKKLT
                     SGPALPGKLADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEV
                     SSDEVLASQEVHDISVAIGIDPDSDDLSQLRYGKICILADADSDGLHIATLLCALFVK
                     HFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNVQRFKGL
                     GEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGD
                     MAEIEV"
     gene            complement(2781..3362)
                     /gene="yqiA"
                     /locus_tag="RHX21_003919"
     CDS             complement(2781..3362)
                     /gene="yqiA"
                     /locus_tag="RHX21_003919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase YqiA"
                     /protein_id="HDV1989040.1"
                     /translation="MSTLLYLHGFNSSPRSAKASLLKNWLAEHHPDVEMIIPQLPPYP
                     SDAAELLESIVLEHGGDSLGIVGSSLGGYYATWLSQCFMLPAVVVNPAVRPFELLTDY
                     LGQNENPYTGQQYVLESRHIYDLKVMQIDPLEAPDLIWLLQQTGDEVLDYRQAVAYYA
                     SCRQTVIEGGNHAFTGFEDYFNPIVDFLGLHHL"
     gene            complement(3362..4189)
                     /gene="cpdA"
                     /locus_tag="RHX21_003920"
     CDS             complement(3362..4189)
                     /gene="cpdA"
                     /locus_tag="RHX21_003920"
                     /EC_number="3.1.4.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3',5'-cyclic-AMP phosphodiesterase"
                     /protein_id="HDV1989041.1"
                     /translation="MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQA
                     VLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMY
                     SALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTL
                     LLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLL
                     ATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY"
     gene            complement(4214..4636)
                     /locus_tag="RHX21_003921"
     CDS             complement(4214..4636)
                     /locus_tag="RHX21_003921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1249 family protein"
                     /protein_id="HDV1989042.1"
                     /translation="MKRYTPDFPEMMRLCEMNFSQLRRLLPRNDAPGETVSYQVANAQ
                     YRLTIVESTRYTTLVTIEQTAPAISYWSLPSMTVRLYHDAMVAEVCSSQQIFRFKARY
                     DYPNKKLHQRDEKHQINQFLADWLRYCLAHGAMAIPVY"
     gene            complement(4637..5266)
                     /gene="nudF"
                     /locus_tag="RHX21_003922"
     CDS             complement(4637..5266)
                     /gene="nudF"
                     /locus_tag="RHX21_003922"
                     /EC_number="3.6.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribose diphosphatase"
                     /protein_id="HDV1989043.1"
                     /translation="MLKPDNLPVTFGKNDVEIIARETLYRGFFSLDLYRFRHRLFNGQ
                     MSHEVRREIFERGHAAVLLPFDPVRDEVVLIEQIRIAAYDTSETPWLLEMVAGMIEEG
                     ESVEDVARREAIEEAGLIVKRTKPVLSFLASPGGTSERSSIMVGEVDATTASGIHGLA
                     DENEDIRVHVVSREQAYQWVEEGKIDNAASVIALQWLQLHHQALKNEWA"
     gene            5471..6952
                     /gene="tolC"
                     /locus_tag="RHX21_003923"
     CDS             5471..6952
                     /gene="tolC"
                     /locus_tag="RHX21_003923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417507.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane channel protein TolC"
                     /protein_id="HDV1989044.1"
                     /translation="MKKLLPILIGLSLSGFSSLSQAENLMQVYQQARLSNPELRKSAA
                     DRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDANGINSNATSASLQLTQSIFDMSK
                     WRALTLQEKAAGIQDVTYQTDQQTLILNTATAYFNVLNAIDVLSYTQAQKEAIYRQLD
                     QTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEQLRQITGNYYPELAAL
                     NVENFKTDKPQPVNALLKEAEKRNLSLLQARLSQDLAREQIRQAQDGHLPTLDLTAST
                     GISDTSYSGSKTRGAAGTQYDDSNMGQNKVGLSFSLPIYQGGMVNSQVKQAQYNFVGA
                     SEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIV
                     DVLDATTTLYNAKQELANARYNYLINQLNIKSALGTLNEQDLLALNNALSKPVSTNPE
                     NVAPQTPEQNAIADGYAPDSPAPVVQQTSARTTTSNGHNPFRN"
     gene            7100..7771
                     /locus_tag="RHX21_003924"
     CDS             7100..7771
                     /locus_tag="RHX21_003924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417509.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1190 family protein"
                     /protein_id="HDV1989045.1"
                     /translation="MKRTKSIRHASFRKNWSARHLTPVALAVATVFMLAGCEKSDETV
                     SLYQNADDCSAANPGKSAECTTAYNNALKEAERTAPKYATREDCVAEFGEGQCQQAPA
                     QAGMAPENQAQAQQSSGSFWMPLMAGYMMGRLMGGGAGFAQQPLFSSKNPASPAYGKY
                     TDATGKNYGAAQPGRTMTVPKTAMAPKPATTTTVTRGGFGESVAKQSTMQRSATGTSS
                     RSMGG"
     gene            7777..8937
                     /locus_tag="RHX21_003925"
     CDS             7777..8937
                     /locus_tag="RHX21_003925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="HDV1989046.1"
                     /translation="MERVSITERPDWREKAHEYGFNFHTMYGEPYWCEDAYYKLTLAQ
                     VEKLEEVTAELHQMCLKVVEKVIASDELMTKFRIPKHTWSFVRQSWLTHQPSLYSRLD
                     LAWDGTGEPKLLENNADTPTSLYEAAFFQWIWLEDQLNAGNLPEGSDQFNSLQEKLID
                     RFVELREQYGFQFLHLTCCRDTVEDRGTIQYLQDCATEAEIATEFLYIDDIGLGEKGQ
                     FTDLQDQVISNLFKLYPWEFMLREMFSTKLEDAGVRWLEPAWKSIISNKALLPLLWEM
                     FPNHPNLLPAYFAEDDHPQMEKYVVKPIFSREGANVSIIENGKTIEAAEGPYGEEGMI
                     VQQFHPLPKFGDSYMLIGSWLVNDQPAGIGIREDRALITQDMSRFYPHIFVE"
     gene            complement(8975..9763)
                     /gene="ygiD"
                     /locus_tag="RHX21_003926"
     CDS             complement(8975..9763)
                     /gene="ygiD"
                     /locus_tag="RHX21_003926"
                     /EC_number="1.13.11.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001356237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4,5-DOPA dioxygenase extradiol"
                     /protein_id="HDV1989047.1"
                     /translation="MSSTRMPALFLGHGSPMNVLEDNLYTRSWQKLGMTLPRPQAIVV
                     VSAHWFTRGTGVTAMETPPTIHDFGGFPQALYDTHYPAPGSPVLAQHLVELLAPVPVT
                     LDKEAWGFDHGSWGVLIKMYPDADIPMVQLSIDSSKPAAWHFEMGRKLAALRDEGIML
                     VASGNVVHNLRTVKWHGDSSPYPWAMSFNEYVKANLTWQGAVEQHPLVNYLDHEGGAL
                     SNPTPEHYLPLLYVLGAWDGQEPITIPVDGIEMGSLSMLSVQIG"
     gene            9906..10679
                     /gene="zupT"
                     /locus_tag="RHX21_003927"
     CDS             9906..10679
                     /gene="zupT"
                     /locus_tag="RHX21_003927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HDV1989048.1"
                     /translation="MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIM
                     LLISLMEMLPAALAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQKSVQPLP
                     KSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPV
                     YAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVVMAAIMAAVAGIMVALSVD
                     ELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG"
     gene            complement(10737..10907)
                     /locus_tag="RHX21_003928"
     CDS             complement(10737..10907)
                     /locus_tag="RHX21_003928"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989049.1"
                     /translation="MFIAWYWIVLIALVVVGYFLHLKRYCRAFRQDRDALLEARNKYL
                     NSTREETAEKVE"
     gene            complement(11168..11821)
                     /gene="ribB"
                     /locus_tag="RHX21_003929"
     CDS             complement(11168..11821)
                     /gene="ribB"
                     /locus_tag="RHX21_003929"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3,4-dihydroxy-2-butanone-4-phosphate synthase"
                     /protein_id="HDV1989050.1"
                     /translation="MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMI
                     FPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAA
                     EGVTTGVSAADRITTVRAAIADGAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDL
                     MTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALVTIEDLVAYRQAHERKAS"
     regulatory      complement(11925..12073)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            12195..12485
                     /gene="ubiK"
                     /locus_tag="RHX21_003930"
     CDS             12195..12485
                     /gene="ubiK"
                     /locus_tag="RHX21_003930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417514.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis accessory factor UbiK"
                     /protein_id="HDV1989051.1"
                     /translation="MIDPKKIEQIARQVHESMPKGIREFGEDVEKKIRQTLQAQLTRL
                     DLVSREEFDVQTQVLLRTREKLALLEQRMSELENRSTEIKKQPDPETLPPTL"
BASE COUNT         3196 a         3330 c         3045 g         2954 t
ORIGIN      
        1 tatcttacgc acaggtaaaa aatatagtta ctggcgaata tagtgcggtc agtaaaatta
       61 tcaccgaaaa ggaaactctc tatccatccg ataagatatt attggttttt gacattgata
      121 atacgttatt aacgagtggc acacgcattg gcggtgatat ctggtatcaa tggcaaaccg
      181 ataaattgcc cttaaagccg gatgactcgc aaaaagttcc ctgcctgtat gaaaatacaa
      241 tcagtatgct ttacgaactt agccctatgc agcttaccga gccacagtta ccgacaatgt
      301 taaaacagtg gcaacaaaag cataccgctt ttgctctgac atcccgtgca ccggatactc
      361 tctttccgac attgcgggaa ttaaagcgaa acggcattga tttttcgtct tccgcactca
      421 ggaagaaaga ggatactttg ccaccctttg aaaaagggaa actcaaacgg tcatggctgt
      481 acagccaggg ggtatttttt tcttccgggc aagataaagg cgtagttctc gattatatgc
      541 tggataaaat ggggaacaaa tatgacgcga ttgtttttat cgatgacggg caagcaaaca
      601 ttcatgcgat gacgaagatg ttctctaagg ataaatggtc ctctacggat tttaccatta
      661 ttcactatac cagagtggag gatgagctta ttaaacaaca aggtgcagta ataacaactg
      721 cacaagcaga aaaaatggct acggactgga aaactctggc tggttcgctg gcaacactat
      781 ttccagatcg taacaaactg tgcccaataa aataatcagc gacaacccgg caaaacacat
      841 gtttgccggg taaagattat taaacctcaa tctccgccat gtcgcctttc tcttgcaacc
      901 agttgcggcg atcttccgag cgtttcttcg ccagcagcat atccatcatc gcgtcagtac
      961 gctgatcgtc ttcatcatcg atagtcaact gcaccagacg gcgagtgttc ggatcaagcg
     1021 tggtttcacg caattgcatc gggttcattt cccccagacc tttaaaacgc tggacgttcg
     1081 gcttgccttt cttgcgtttt aattgctcaa gtacgccctc tttctcttct tccgtcagcg
     1141 cgtaataaac ctctttcccg agatcaatac ggtagagcgg tggcagtgcg acgtaaacgt
     1201 gaccgtgttt caccaacgcg cggaagtgtt ttacgaacaa agcgcagagc agcgtggcaa
     1261 tgtgcagacc atcagagtcc gcatccgcga ggatacagat tttgccataa cgaagctggc
     1321 tcagatcgtc gctgtcagga tcgataccga tcgctaccga aatatcatgc acttcctgcg
     1381 aggccagcac ttcgtcggaa gaaacttccc aggtgttaag gatcttacct ttcagtggca
     1441 tgatcgcctg atattcgcga tcgcgcgcct gcttggcaga tccgcctgcg gagtcacctt
     1501 ccacaaggaa cagttcggta cggttaagat cctgcgcggt acagtcagcc agtttgccag
     1561 gcagtgctgg gccgctggtc agctttttgc gcaccacttt tttagccgca cgcatacggc
     1621 gctgggcgct ggaaatcgcc atctccgcca gcaactccgc cgcctgaacg ttctggttca
     1681 gccacaggat aaaggcatct ttcaccacgc cagaaacaaa tgccgcgcac tgacgcgaag
     1741 agagacgctc tttggtctgc ccggcaaact gcggatcctg catttttact gacagcacat
     1801 aggcgcagcg atcccagata tcttccgccg acaactttac accgcgcggc agaatgttgc
     1861 ggtattcaca gaactcacgc atcgcgtcca acaggccctg acgcagaccg ttaacgtgcg
     1921 taccgccctg catcgttggg ataaggttga cgtagctttc ggtcagcagt tcaccgcctt
     1981 ccggcagcca cagtagcgcc cagtccacag cttcagtatc gccagcgaaa ttaccgataa
     2041 acggtttttc tggcagcgtc ggtaaaccgt ttaccgcttc cgccaggtaa tcattcagac
     2101 cgtcctgata gcaccagcgc tgttcggtgt tgttgatctc atctttaaag gtaatctcaa
     2161 cgccggggca cagtactgct ttggccttca gcacatgcgt caggcgtgaa acagaaaaac
     2221 gcgggctgtc aaagaaggtt tcatccggcc agaagtgcac gctggtaccg gtattgcgtt
     2281 taccgcaagt gccgacaacc tgtaaatcct gcaccttttc gccattttca aaggcgatgt
     2341 tataaacctg accatcgcgg cgcacgttaa cttctacgcg cttcgacagg gcgttaacca
     2401 ccgaaatccc cacgccatgc aggccgccag agaactggta atttttgtta gagaatttac
     2461 cgcctgcatg cagacggcaa agaatcagtt caaccgccgg tacaccctct tccgggtgaa
     2521 tatccaccgg catcccgcgc ccatcgtcaa taacttctaa cgactggtca gcatgtaaga
     2581 ttacatccac gcgttttgcg tgacccgcca gtgcttcatc gacactgtta tcaataactt
     2641 cttgccccaa atggttaggg cgagtggtat cggtatacat ccccggacgg cggcgaaccg
     2701 gctcaagccc ggtgagtacc tcaatggcat cagcgttata agtttgcgtc atggtttaag
     2761 ttagcaattc gagttgatcg tcagagatgg tgcagaccaa gaaaatcgac gatcgggttg
     2821 aaataatctt cgaagcccgt gaatgcgtgg ttgccgcctt ctatgacagt ctggcggcag
     2881 gaagcgtagt acgccaccgc ctggcggtaa tccagcactt catctcccgt ctgttgcagc
     2941 agccagatca aatccggcgc ttccagcggg tcaatctgca tgactttgag atcgtaaata
     3001 tggcgtgact ctagcacata ttgctgcccg gtgtaggggt tctcgttctg accgagatag
     3061 tccgtcagca gttcaaacgg gcgcaccgcc gggtttacca ccactgcggg cagcataaaa
     3121 cattgtgaca accaggtggc gtaatatccc cccagtgacg aaccgacaat acccagcgaa
     3181 tcgccgccat gttccaggac aatggattcc agcagctctg ccgcgtcgga aggatacggc
     3241 ggcaactgcg gaatgatcat ctcaacgtca gggtgatgtt ccgccagcca gttttttaac
     3301 aagctcgctt ttgcagagcg cggcgagctg ttgaaaccgt gtaaataaag aagcgtagac
     3361 atcagtagcc ttctgaagcg gtatcaggtt ggaaacgtgt gtccgccagg cgatgcacct
     3421 cggtggtcag cgtgccatca gcatgtaact cgagagtacg ccagccgggc gcgatggtgt
     3481 ccagcgtaaa gttggaacag tgcggcttaa actgcacaca ggtcgacggc gttgccagca
     3541 ggcggcgacc gttccagtcg agatccagct cctgatgaat atgaccgcac agcaagtatt
     3601 tgacgtgcgg aaacttcgcc agcacggtat ccagttcgcc cgcgttacgc aggctgtgtt
     3661 gatcaagcca actacaaccc gcaggtagcg gatgatgatg cagcagcagc aacgtatggc
     3721 gttctggcgc atcggccagt ttacgttcca gccactcaag ctgaaactcg ctcagctcac
     3781 cgtgcggcac gccaaacacc tggctatcca gcaacaggat ttgccattgc tcaccaataa
     3841 acacgcgctt cgccggggag atacccgcat cctgtaacgc gctgtacatc gcgggctgga
     3901 aatcgtggtt gcccggcagc cagacgcagg gcgcacgaaa acttgcgatg ccttcagcga
     3961 aatgctgata ggccgcagag gattgatcct gcgctaaatc acctgtcgcg acaatcaggt
     4021 cgaattcgtg ctgatgtgga cgaatcgcct ccagcaccgc ctggtagctt tcccaggtgt
     4081 ttacccctaa cagggcttcg tgcttttgtg caaacaggtg agtatcggta atttgtaaaa
     4141 tcctgactct ggcctcacca gccagaggaa gggttaacag gctttccaaa tggtgtcctt
     4201 aggtttcacg acgctagtaa accggaatcg ccatcgctcc atgtgctaaa cagtatcgca
     4261 accagtccgc taaaaactgg ttaatttgat gcttttcgtc gcgttgatgc aactttttat
     4321 taggataatc ataccgcgct ttgaagcgaa aaatctgctg gcttgaacac acttcagcca
     4381 ccatcgcgtc atgatacaga cgcaccgtca ttgacggaag gctccagtaa ctgatcgcgg
     4441 gcgcagtctg ttctattgtc accagggtag tgtatcgggt cgattccaca atcgtcagcc
     4501 gatattgtgc gtttgccacc tgatagctta cagtttcgcc gggtgcgtca ttgcgcggta
     4561 acaaacggcg caattgtgaa aagttcatct cgcacaggcg catcatttca ggaaagtcag
     4621 gtgtgtaacg cttcatttat gcccactcat tttttaacgc ttgatgatgc agctgcagcc
     4681 attgcaaagc gatgaccgac gctgcgttgt cgattttccc ctcttctacc cactggtatg
     4741 cctgttcccg gcttaccaca tgaacgcgaa tatcttcgtt ttcatcagcc agaccatgaa
     4801 taccgcttgc ggtcgtggcg tccacttcgc ccaccataat tgacgaacgc tcactggtgc
     4861 cccccgggct tgccaggaaa cttaacaccg gtttggtccg tttgactatc agtcccgcct
     4921 cttcaatcgc ttcgcgacgg gcaacatctt ccacactttc accctcttct atcatcccgg
     4981 caaccatctc cagtagccag ggggtttcac tggtgtcgta tgcggcaatc cgaatctgct
     5041 caatcagcac aacttcatca cgcactgggt caaagggtag caagactgcg gcgtgaccgc
     5101 gctcaaaaat ttccctccgt acctcatgac tcatttgccc gttgaataaa cgatgacgaa
     5161 atctataaag atctaatgaa aaaaagccgc gataaagtgt ttctcgtgca ataatttcta
     5221 catcgttttt gccaaatgta acgggcaggt tgtctggctt aagcattgtt aatgtcctgg
     5281 cactaatagt gaattaaatg tgaatttcag cgacgtttga ctgccgtttg agcagtcatg
     5341 tgttaaattg aggcacatta acgccctatg gcacgtaacg ccaacctttt gcggtagcgg
     5401 cttctgctag aatccgcaat aattttacag tttgatcgcg ctaaatactg cttcaccaca
     5461 aggaatgcaa atgaagaaat tgctccccat tcttatcggc ctgagccttt ctgggttcag
     5521 ttcgttgagc caggccgaga acctgatgca agtttatcag caagcacgcc ttagtaaccc
     5581 ggaattgcgt aagtctgccg ccgatcgtga tgctgccttt gaaaaaatta atgaagcgcg
     5641 cagtccatta ctgccacagc taggtttagg tgcagattac acctatagca acggctaccg
     5701 cgacgcgaac ggcatcaact ctaacgcgac cagtgcgtcc ctgcagttaa ctcaatccat
     5761 ttttgatatg tcgaaatggc gtgcgttaac gctgcaggaa aaagcagcag ggattcagga
     5821 cgtcacatat cagaccgatc agcaaacctt gatcctcaac accgcgaccg cttatttcaa
     5881 cgtgttgaat gctattgacg ttctttccta tacacaggca caaaaagaag cgatctaccg
     5941 tcaattagat caaaccaccc aacgttttaa cgtgggcctg gtagcgataa ccgacgtgca
     6001 gaacgcccgc gcgcagtacg ataccgtgct ggcgaacgaa gtgaccgcac gtaataacct
     6061 tgataacgcg gtagagcagc tgcgccagat caccggtaac tactatccag aactggcagc
     6121 gctgaatgtc gaaaacttta aaaccgacaa accacagccg gttaacgcgc tgctgaaaga
     6181 agccgaaaaa cgcaacctgt cgctgttaca ggcacgcttg agccaggacc tggcgcgcga
     6241 gcaaattcgc caggcgcagg atggtcactt accgacgctg gatttaacgg cttctaccgg
     6301 gatttctgac acctcttata gcggttcgaa aactcgtggt gccgctggta cccagtatga
     6361 cgacagcaat atgggccaga acaaagtggg cctgagcttc tcgctgccga tttatcaggg
     6421 cggaatggtt aactcgcagg tgaaacaggc ccagtacaac tttgttggtg ccagcgagca
     6481 actggaaagc gcgcatcgta gcgtcgtgca aaccgtacgt tcctccttca acaacattaa
     6541 tgcatctatc agtagcatta acgcctacaa acaagccgta gtttccgctc aaagctcatt
     6601 agacgcgatg gaagcgggct actcggtcgg tacgcgtacc attgttgatg tgttggatgc
     6661 aaccaccacg ctgtacaacg ctaagcaaga gctggcaaat gcgcgttata actacctgat
     6721 taatcagctg aatattaagt cagccctggg tacgttgaac gagcaggatc tgctggcact
     6781 gaacaatgcg ctgagcaaac cggtttccac taatccggaa aacgttgccc cgcaaacgcc
     6841 ggaacagaat gctattgctg atggttatgc gcctgatagc ccggcacccg tcgttcagca
     6901 aacatccgca cgcactacca ccagtaacgg tcataaccct ttccgtaact gatgacgacg
     6961 acggggcttc ggccccgtct gaacgtaagg caacgtaaag atacgggtta tctgccgcat
     7021 tcttccccct tctcgcttca atttcgacca gccatcctct attctgatgg gtatttacca
     7081 ctggtcccgg aagacaaaaa tgaaacggac aaaatccata cgccacgcat cgttccgcaa
     7141 aaactggagc gcgcgccatc tgacaccagt cgctctcgcg gttgccactg tttttatgct
     7201 ggctggctgt gaaaagagtg atgaaacagt gtctctctat caaaatgctg acgactgttc
     7261 agctgcaaac ccaggcaaaa gcgccgaatg taccaccgcg tacaacaatg cgctgaaaga
     7321 agccgaacgt actgcgccga aatacgccac ccgtgaagac tgtgttgctg aatttggtga
     7381 aggtcagtgc cagcaggcac cagcccaggc tggcatggca ccagaaaacc aggcgcaggc
     7441 ccagcaatcc agcgggagtt tctggatgcc gctgatggcc ggttacatga tggggcgtct
     7501 gatgggcggc ggcgcgggat ttgcacagca gccgctgttc tcctcgaaaa acccagccag
     7561 cccggcttac ggtaaatata ccgacgcgac gggtaaaaac tatggcgcag cccagccagg
     7621 ccgcaccatg accgtaccga agacagccat ggcaccaaaa ccggcgacca ccactaccgt
     7681 tacccgtggc ggttttggtg aatctgttgc caaacaaagc actatgcagc gtagcgcaac
     7741 tggcacctct tctcgttcaa tgggtggctg ataccgatgg aaagagtcag tattaccgag
     7801 cgcccggact ggcgtgagaa agcccacgaa tacggtttca attttcacac catgtacggc
     7861 gagccgtact ggtgtgaaga tgcttactac aagttgaccc tcgcccaggt tgaaaagctg
     7921 gaagaagtca ccgccgaact gcaccagatg tgcctgaaag tggtggaaaa agtgatcgcc
     7981 agcgatgagc tgatgaccaa attccgcatt ccaaaacaca cctggagttt tgtgcgccag
     8041 tcatggctga cgcaccagcc atcgctttat tcgcgtcttg atctggcgtg ggatggcact
     8101 ggcgaaccta aacttctgga aaataacgcc gatacgccaa cgtcactata cgaggcggcg
     8161 ttctttcagt ggatctggct ggaagatcag cttaacgccg gtaacttgcc ggagggcagc
     8221 gaccagttta acagtctgca agaaaaactg atcgatcgct tcgttgagct gcgtgaacag
     8281 tatggcttcc agtttctgca tctcacctgc tgtcgcgaca cggtggaaga tcgcggaacc
     8341 attcagtatt tgcaggactg cgcaacggaa gctgaaattg ctactgagtt cctctacatc
     8401 gatgatatcg ggttaggtga aaaaggtcag ttcacggatt tacaggatca ggtaatttcc
     8461 aacctgttca agctgtatcc gtgggaattt atgttgcgtg agatgttttc caccaagctg
     8521 gaggatgcag gcgtacgctg gctggaacca gcgtggaaga gcattatctc caacaaggca
     8581 cttctaccgc tactgtggga gatgttcccg aatcacccga acctgctgcc cgcttatttt
     8641 gcggaagatg atcatccgca aatggaaaaa tatgtggtta aaccgatctt ctcccgtgaa
     8701 ggcgcaaacg tgtcgatcat tgaaaacggc aaaaccattg aagcagcgga aggtccgtat
     8761 ggcgaagaag ggatgattgt tcagcaattc cacccgttac cgaaattcgg cgacagctat
     8821 atgctgattg gtagctggct ggtgaacgat caacccgccg gaattggcat tcgtgaagac
     8881 cgtgcattga tcacccagga tatgtctcgg ttttatccac atatttttgt tgagtaatca
     8941 atgatgccgg atggcattcg ccatccggta attgttaacc tatctgcacc gacagcatac
     9001 tcaggctgcc catttctata ccatcgaccg gaatggtaat tggctcctgc ccatcccacg
     9061 cacctaagac atacaacaac ggcagatagt gctccggcgt tgggttcgat aacgcgccac
     9121 cttcatggtc gaggtaattc accagaggat gctgctctac cgccccttgc cacgtcagat
     9181 tcgctttcac atactcatta aacgacatcg cccaaggata tggtgaacta tcaccgtgcc
     9241 acttcactgt acgcaggtta tgcaccacgt tgccactggc gaccaacatt attccttcat
     9301 ctcgcagcgc tgccagtttg cgccccattt cgaaatgcca ggcggcaggt ttgctactgt
     9361 cgatactcaa ctgcaccatc gggatatcgg cgtcaggata catcttaatc agcacgcccc
     9421 aggaaccgtg gtcaaagccc caggcttctt tatccagcgt caccgggacc ggtgctaaca
     9481 gctcaaccag atgctgtgcc agcacaggcg aacccggagc aggataatgc gtatcgtaca
     9541 gcgcctgcgg gaagccacca aagtcatgaa tcgtgggcgg cgtctccatc gcggtcactc
     9601 ctgttccacg ggtaaaccag tgagccgaaa ccaccacaat cgcttgcggg cgtggcaatg
     9661 tcatccccaa cttctgccag ctgcgggtat acaaattatc ttccagcacg ttcatcggac
     9721 taccgtgacc taaaaacaat gctggcatac gtgttgaaga catgatgata tccttaacta
     9781 aaggtgtcat tttgatatcc tcacaatacg cttgttcggc ggagtaagaa cccggataac
     9841 aatgatgatg atcatcagtt attttgacga tctgcctgaa ggtgaagatt tataaggagt
     9901 tgtcgatgtc agtacctctc attctgacca tactggcggg ggcagccacg tttattggcg
     9961 cgtttctcgg cgttctcggg caaaaaccct cgaaccgctt actggcgttt tcgctaggat
    10021 ttgcggcggg gatcatgttg ctcatctcat taatggaaat gcttcctgcc gcactagcag
    10081 ctgaaggaat gtcgcctgtg ttgggttatg gaatgtttat cttcggtctg cttggctatt
    10141 ttggcctgga ccgcatgttg ccacatgcgc atccgcagga tttaatgcaa aaatcggtgc
    10201 agccgttgcc aaaatcgatc aagcgcacag ccattctgct cactctcggc atcagtctgc
    10261 ataacttccc ggaagggatt gccacctttg tcacggcgag cagcaacctg gagctgggat
    10321 ttggcatcgc actggccgtc gcgttgcaca atattcctga aggtctggcg gttgcaggcc
    10381 cggtttatgc agcaacgggt tctaaacgca cggcaattct gtgggcgggg atttctggat
    10441 tggcagaaat tcttggtggt gtgctggcgt ggttaatcct cggtagcatg atttcccccg
    10501 tggtcatggc ggcaatcatg gcggcggttg caggaattat ggtggcgctc tcggttgatg
    10561 aattaatgcc gctcgccaaa gagattgacc ctaataataa ccccagctat ggcgtactat
    10621 gtggaatgtc agtgatggga ttcagtttag tgctgctaca aacggcggga attggttaaa
    10681 agcaacatca gaagttggcc agcgcatgga caacttctgc tagcttcact aaagccttat
    10741 tctacctttt cggctgtctc ttctctcgta ctgtttaagt atttgttccg cgcttcaagc
    10801 agtgcgtctc tgtcctggcg aaacgcccga caataacgtt tcaaatgcag gaaataaccc
    10861 accacaacaa gagcaatcaa tacaatccag taccaggcga taaacatcct tttaccctta
    10921 atatttaaca atactaaaca tttagcgcat aaatttcaca tatccttttt cggatatatt
    10981 catatggtcg cataataacg gaacaattat atgattttga tcataatgaa aaagaatgcc
    11041 tgatattaat gaaattttct catagaaaga gaagcggaat taacatcttg catagcaggg
    11101 caaaataaaa accgaagcca gctacaactt cggtttcttg attaaggcag taattaagca
    11161 gcggttttca gctggcttta cgctcatgtg cctgacggta tgccaccagg tcttcaatag
    11221 tcacgagcgc catattgtgt ttattggcaa actcaatgca ctctggtgca cgcgccatcg
    11281 tgccatcgtc attagtcaac tcacacagca caccagccgg tttaaagcct gccagcgtca
    11341 tcaaatcaat agtcgcttca gtatgaccgc cacgcgtcag tacaccacct gcctgcgcgc
    11401 gaagtgggaa aacgtggccc gggcgattca gatcagaagg ttttgcgcca tcggcaatcg
    11461 ctgcgcgaac ggtcgtaatt cgatcagcgg cagaaacacc ggtagtcaca ccttcagccg
    11521 cttcaatggt cacggtaaaa ccggtgccat aggcgctggt gttattttct accatcattg
    11581 gcagatcaag ttgtttacgg cgatcttcag tgatgcacag gcaaacaata ccgctaccgt
    11641 ggcgaatggt cagcgccatc tgctcaacgg tcatggtttc tgccgggaag atcatatcgc
    11701 cttcgttttc acggtcttca tcatcaagca ccattacacc gcgtccttca cgcagcgcag
    11761 ccagtgcatt ttcaacacgt tcgaaaggcg taccaaaaga ggaaagtagc gtctgattca
    11821 tggtaaaaaa acctcactaa aattatggtt accagaatca gggcagtctt aggagtggcg
    11881 gcatatagcc aaaataacgt gagcgggtcc atgcccgaca gaatcgttac tctctcccat
    11941 ccggactcta accgtcggcc ccggaattac accggatctg ctgtcctttg agttcgcacc
    12001 caaagcgctc gcgggctttc aactgagttg atttaccgcc ggtggggaat ttcgccccgc
    12061 cctgagaata agcggattca ctataacgct aatgattagc ggcagcaacg catagcttca
    12121 cataattctg gtttatgact tacccttatc gcactacaat ggcactcaac acctatcagt
    12181 acagggaaac tacaatgatt gacccgaaaa aaattgagca aatcgctcgc caggttcacg
    12241 aatcaatgcc taaaggaatc agggagttcg gggaagatgt ggagaaaaaa atccgccaaa
    12301 ccctacaagc tcagctgacg cgcctcgacc ttgtaagccg tgaagagttc gacgtccaaa
    12361 cgcaagtcct gttacggact cgtgagaaac tggcgctgct tgaacaaaga atgagcgaac
    12421 tggaaaatcg cagtactgag attaaaaagc agccagatcc agagactctc cccccaacgc
    12481 tgtaaacatt tgtctttaat gcactgtaaa ttatgaatta atctt
//
LOCUS       DAPGUL010000131        12134 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.134, whole genome shotgun sequence.
ACCESSION   DAPGUL010000131 DAPGUL010000000
VERSION     DAPGUL010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12134
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.134"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            234..1004
                     /locus_tag="RHX21_003931"
     CDS             234..1004
                     /locus_tag="RHX21_003931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418784.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter ThrE family protein"
                     /protein_id="HDV1989052.1"
                     /translation="MQTEQQRAVTRLCIQCGLFLLQHGAESALVDELSSRLGRALGMD
                     SVESSISSNAIVLTTIKDGQCLTSTRKNHDRGINMHVVTEVQHIVILAEHHLLDYKGV
                     EKRFSQIQPLRYPRWLVALMVGLSCACFCKLNKGGWDGAVITFFASTAAMYIRQLLAQ
                     RHLHPQINFCLTAFAATTISGLLLQLPTFSNTPTIAMAASVLLLVPGFPLINAVADMF
                     KGHINTGLARWAIASLLTLATCVGVVMALTIWGLRGWV"
     gene            995..1468
                     /locus_tag="RHX21_003932"
     CDS             995..1468
                     /locus_tag="RHX21_003932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418783.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HDV1989053.1"
                     /translation="MGVIEFLLALAQDMILAAIPAVGFAMVFNVPVRALRWCALLGAI
                     GHGSRMILMTSGLNIEWSTFMASMLVGTIGIQWSRWYLAHPKVFTVAAVIPMFPGISA
                     YTAMISAVKISQLGYSEPLMITLLTNFLTASSIVGALSIGLSIPGLWLYRKRPRV"
     gene            1575..2114
                     /gene="dnaT"
                     /locus_tag="RHX21_003933"
     CDS             1575..2114
                     /gene="dnaT"
                     /locus_tag="RHX21_003933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaT"
                     /protein_id="HDV1989054.1"
                     /translation="MSSRVLTPDVVGIDALVHDHQTVLAKAEGGVVAVFANNAPAFYA
                     VTPARLAELLALEEKLARPGSDVALDDQLYQEPQAAPVAVPMGKFAMYPDWQPDADFI
                     RLAALWGVALREPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRASNGGLPK
                     RDVNTVSEPDSQIPPGFRG"
     gene            2117..2854
                     /gene="dnaC"
                     /locus_tag="RHX21_003934"
     CDS             2117..2854
                     /gene="dnaC"
                     /locus_tag="RHX21_003934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaC"
                     /protein_id="HDV1989055.1"
                     /translation="MKNVGDLMQRLQKMMPAHIKPAFKTGEELLAWQKEQGAIRSAAL
                     ERENRAMKMQRTFNRSGIRPLHQNCSFENYRVECEGQMNALSKARQYVEEFDGNIASF
                     IFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFRNSGTSEEQLLNDL
                     SNVDLLVIDEIGVQTESKYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMTKLLGERVM
                     DRMRLGNSLWVIFNWDSYRSRVTGKEY"
     gene            2903..3397
                     /locus_tag="RHX21_003935"
     CDS             2903..3397
                     /locus_tag="RHX21_003935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2501 domain-containing protein"
                     /protein_id="HDV1989056.1"
                     /translation="MMKTVKHLLCCAIAASALISTGVHAASWKDALSSAASELGNQNS
                     TTQEGGWSLASLTNLLSSGNQALSADNMNNAAGILQYCAKQKLASVTDAENIKNQVLE
                     KLGLNSEEQKEDTNYLDGIQGLLKTKDGQQLNLDNIGTTPLAEKVKTKACDLVLKQGL
                     NFIS"
     gene            3651..5942
                     /gene="opgB"
                     /locus_tag="RHX21_003936"
     CDS             3651..5942
                     /gene="opgB"
                     /locus_tag="RHX21_003936"
                     /EC_number="2.7.8.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418779.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerol--membrane-oligosaccharide
                     glycerophosphotransferase"
                     /protein_id="HDV1989057.1"
                     /translation="MSELLSFALFLASVLIYAWKAGRNTWWFAATLTVLGLFVVLNIT
                     LFASDYFTGDGINDAVLYTLTNSLTGAGVSKYILPGIGIVLGLTAVFGALGWILRRRR
                     HHPHHFGYSLLALLLALGSVDASPAFRQITELVKSQSRDGDPDFAAYYKEPSKTIPDP
                     KLNLVYIYGESLERTYFDNEAFPDLTPELGALKNEGLDFSHTQQLPGTDYTIAGMVAS
                     QCGIPLFAPFEGNASASVSSFFPQNICLGDILKNSGYQNYFVQGANLRFAGKDVFLKS
                     HGFDHLYGSEELKSVVADPHYRNDWGFYDDTVLDEAWKKFEELSRSGQRFSLFTLTVD
                     THHPDGFISRTCNRKKYDFDGKPNQSFSAVSCSQENIAAFINKIKASPWFKDTVIVVS
                     SDHLAMNNTAWKYLNKQDRNNLFFVIRDDKPQQETLAVKRNTMDNGATVLDILGGDNY
                     LGLGRSSLSGQSMSEIFLNIKEKTLAWKPDIIRLWKFPKEMKEFTIDQQKNMIAFSGS
                     HFRLPLLLRVSDKRVEPLPESEYSAPLRFQLADFAPRDNFVWVDRCYKMAQLWAPELA
                     LSTDWCVSQGQLGGQQIVQHVDKTMWKGKTAFKDTVIDMARYKSNVDTLKIVDNDIRY
                     KADSFIFNVAGAPEEVKQFSGISRPESWGRWSNAQLGDEVKIEYKHPLPKKFDLVITA
                     KAYGNNASRPIPVRVGNEEQTLVLGNEVTTTTLHFDNPTDADTLVIVPPEPVSTNEGN
                     ILGHSPRKLGIGMVEIKVVEREG"
     gene            complement(6081..7103)
                     /gene="lgoD"
                     /locus_tag="RHX21_003937"
     CDS             complement(6081..7103)
                     /gene="lgoD"
                     /locus_tag="RHX21_003937"
                     /EC_number="1.1.1.414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418778.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-galactonate oxidoreductase"
                     /protein_id="HDV1989058.1"
                     /translation="MSTMNVLICQQPKELVWKQREIPIPGDNEALIKIKSVGICGTDI
                     HAWGGNQPFFSYPRVLGHEICGEIVGLGKNIADLKNGQQVAVIPYVACQQCPACKSGR
                     TNCCEKISVIGVHQDGGFSEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAI
                     APGEQVLVVGAGPIGLGAAAIAKADGAQVVVADTSPARREHVATRLELPLLDPSAEDF
                     DAQLRAQFGGSLAQKVIDATGNQHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHK
                     KETTMMGSRNATPEDFAKVGRLMAEGKITADMMLTHRYPFATLAETYERDVINNRELI
                     KGVITF"
     gene            7242..8156
                     /locus_tag="RHX21_003938"
     CDS             7242..8156
                     /locus_tag="RHX21_003938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDV1989059.1"
                     /translation="MSRSQNLRHNVINQVIDDMARGHIPSPLPSQSALAEMYNISRTT
                     VRHILSHLRECGVLTQVGNDYVIARKPDHDDGFACTTASMSEQNKVFEQAFFTMINQR
                     QLRPGETFSELQLARAAGVSPVLVREYLLKFGRYNLIHSEKRGQWSMKQFDQSYAEQL
                     FELREMLETHSLQHFLNLPDHDPRWLQAKTMLERHRLLRDNIGNSFRMFSQLDRDFHS
                     LLLSAADNIFFDQSLEIISVIFHFHYQWDESDLKQRNIIAVDEHMTILSALICRSDLD
                     ATLALRNHLNSAKQSMIRSINENTRYAH"
     gene            8371..9732
                     /locus_tag="RHX21_003939"
     CDS             8371..9732
                     /locus_tag="RHX21_003939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1989060.1"
                     /translation="MEKENITLDPRSSFTPSSSADIPVPPDGLVQRSTRIKRIQTTAM
                     LLLFFAAVINYLDRSSLSVANLTIREELGLSATEIGALLSVFSLAYGIAQLPCGPLLD
                     RKGPRLMLGLGMFFWSLFQAMSGMVHNFTQFVLVRIGMGIGEAPMNPCGVKVINDWFN
                     IKERGRPMGFFNAASTIGVAVSPPILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYR
                     NREHVELTAVEQAYLNAGSVNARRDPLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLY
                     LAWLPGYLQTAYNLDLKSTGLMAAIPFLFGAAGMLVNGYVTDWLVKGGMAPIKSRKIC
                     IIAGMFCSAAFTLVVPQATTSMTAVLLIGMALFCIHFAGTSCWGLIHVAVASRMTASV
                     GSIQNFASFICASFAPIITGFIVDTTHSFRLALIICGCVTAAGALAYIFLVRQPINDP
                     RKD"
     gene            complement(9781..11445)
                     /gene="tsr"
                     /locus_tag="RHX21_003940"
     CDS             complement(9781..11445)
                     /gene="tsr"
                     /locus_tag="RHX21_003940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein"
                     /protein_id="HDV1989061.1"
                     /translation="MLKRIKIVTSLLLVLAVFGLLQLTSGGLFFNALKNDKENFTVLQ
                     TIRQQQSTLNGSWVALLQTRNTLNRAGIRYMMDQNNIGSGSTVAELMQSASISLKQAE
                     KNWADYEALPRDPRQSTAAAAEIKRNYDIYHNALAELIQLLGAGKINEFFDQPTQGYQ
                     DGFEKQYVAYMEQNDRLYDIAVSDNNASYSQAMWILVGVMIVVLAVIFAVWFGIKASL
                     VAPMNRLIDSIRHIAGGDLVKPIEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANA
                     IYSGASEIATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASHLALSAS
                     ETAQRGGKVVDNVVQTMRDISTSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQ
                     GRGFAVVAGEVRNLAQRSAQAAREIKSLIEDSVGKVDVGSTLVESAGETMAEIVSAVT
                     RVTDIMGEIASASDEQSRGIDQVGLAVAEMDRVTQQNAALVEESAAAAAALEEQASRL
                     TEAVAVFRIQQQQQQQRETSAVVKTVTPAAPRKMAVADSEENWETF"
     gene            complement(11564..12010)
                     /gene="hpaR"
                     /locus_tag="RHX21_003941"
     CDS             complement(11564..12010)
                     /gene="hpaR"
                     /locus_tag="RHX21_003941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoprotocatechuate degradation operon regulator
                     HpaR"
                     /protein_id="HDV1989062.1"
                     /translation="MHDSLTIALLQAREAAMSYFRPIVKRHNLTEQQWRIVRILAESP
                     SMDFHDLAYRACILRPSLTGILTRMERDGLVLRLKPINDQRKLYISLTKEGQALYNRA
                     QTQIEEAYRQIEAQFTAEKMQQLTHLLEEFIALGNSRQEAIPGDNE"
BASE COUNT         2946 a         3197 c         2956 g         3035 t
ORIGIN      
        1 attatcctga ttcgtaaagg ccaaacaata aattcattat agtgataata ttcatgtgat
       61 agtttgtttg cggcgagaga taattcgctt tttatcaccg agcttgtccc gataaccagg
      121 attaatcagc gcaattttga tcttaaccta ccgcaaaaca accgtgcttc atgatacaaa
      181 tggattctca ttatctgaac aatacgcagc acgtctatga caaagggcga gttatgcaaa
      241 ctgagcaaca gcgagccgta acacggcttt gtatccagtg tggattattt cttttgcaac
      301 atggtgcgga aagcgcgttg gttgatgagc tttcctcacg actgggtcgg gcgttgggga
      361 tggacagcgt cgaaagttct atctcttcga acgccatagt gctgacaacc attaaagatg
      421 ggcaatgcct gacatcgaca cgtaaaaatc acgatcgcgg cattaatatg catgtggtga
      481 ctgaagtcca gcacattgtg attctggcgg agcaccatct gctggattac aaaggcgtag
      541 agaaacgatt tagccaaatt cagccattac gttacccaag atggctggta gccttaatgg
      601 ttggcctttc ttgtgcctgt ttctgtaaac tcaataaagg tggctgggat ggtgccgtca
      661 tcaccttctt tgccagtacg gccgcgatgt atatccgcca gctgctggca caacgtcatc
      721 ttcatccaca aatcaacttt tgccttaccg ctttcgccgc caccaccatt tccggattgc
      781 ttttgcaact tcccactttc agcaatacac ccactatcgc gatggccgcc agcgttctgc
      841 tgctggtgcc gggatttccg ttgattaatg ccgtcgccga tatgtttaaa ggccacatca
      901 ataccggact ggcacgctgg gcgatcgcca gtctgctgac actggctacc tgcgtcggcg
      961 tagtgatggc actgacgatt tgggggctac gcggatgggt gtgatcgaat ttctgttagc
     1021 gttggcgcag gatatgatcc tcgccgccat tcctgcggtc ggctttgcga tggtgttcaa
     1081 cgttcccgtt cgggcgttac gctggtgtgc gctgcttggc gcgattggtc atggttcacg
     1141 aatgatctta atgaccagcg ggctgaatat tgagtggtca acttttatgg cttctatgct
     1201 ggtcggcacc attggtattc aatggtcgcg ctggtatctg gcgcatccga aagtgtttac
     1261 cgtggcggcc gttatcccta tgttcccggg catatcggct tataccgcaa tgatttcggc
     1321 ggtaaaaatc agccagttag gttacagcga accgttgatg attaccctgt taaccaactt
     1381 tcttacagct tcatcgattg ttggtgcgtt atccatcggt ctttccattc ctggattatg
     1441 gttgtaccgc aagcgccctc gcgtataaaa ttgcctcgct taagcacacg gatgagagac
     1501 agcctcctct cctccgtgtg ttactataaa agttatctcc cttctcgttc atcgttccat
     1561 atttgagaaa cagtatgtct tccagagttt tgaccccgga cgtcgttggt attgacgccc
     1621 tggtacacga tcaccaaacc gttctggcaa aagctgaagg cggtgtggtt gccgtatttg
     1681 ctaacaatgc cccggcgttt tatgccgtca cgcctgcacg cctggctgaa ctgctggcgc
     1741 tggaagaaaa gctggcgcgt ccgggaagcg atgtcgctct ggacgatcaa ctctatcagg
     1801 aaccgcaagc cgctcccgtt gctgtcccca tggggaaatt cgccatgtat ccggactggc
     1861 aacccgatgc cgactttatc cgcctggcgg cgctatgggg cgtggcgcta agagagccgg
     1921 tgaccaccga agaactggcc tcattcattg cctactggca ggcggaaggt aaagtctttc
     1981 accatgtgca gtggcaacaa aaactggcgc gcagcctgca aatcggtcgt gccagcaacg
     2041 gcggactgcc gaaacgagat gtgaatacgg tcagcgaacc tgacagccaa attccaccag
     2101 gattcagagg gtaacgatga aaaacgttgg cgacctgatg caacgcctgc aaaaaatgat
     2161 gcctgcccat atcaaacctg cattcaaaac gggtgaagag ctactggcct ggcagaaaga
     2221 acaaggagcg atccgctccg ccgctctcga acgtgaaaat cgggcgatga aaatgcagcg
     2281 cacctttaac cgctccggta ttcggccact gcatcagaac tgctcctttg agaactatcg
     2341 cgttgagtgt gaagggcaga tgaatgcgtt aagcaaagcg cgccagtacg tcgaagagtt
     2401 tgacggcaac atcgccagct tcatcttttc tggtaagcca ggaaccggca aaaaccatct
     2461 ggcggcggca atctgcaacg agctgctgct acgcggtaaa tccgtattga tcatcaccgt
     2521 ggccgatatt atgtcggcga tgaaagatac cttcaggaat agcggtacca gtgaagaaca
     2581 actgcttaac gatctgagca acgttgatct gctggtgatc gatgagatcg gcgtgcagac
     2641 cgaatcgaaa tacgaaaaag tgatcatcaa ccagatcgtc gatcgccgct cttcttccaa
     2701 acgcccaacc gggatgctga ccaacagtaa tatggaagag atgaccaagt tgctgggcga
     2761 acgcgtgatg gaccgtatgc gcctgggtaa cagtttgtgg gtgatcttca actgggatag
     2821 ctaccgtagc cgggtaacag gtaaagagta ttaatccccg tttctggcgg tatactgcga
     2881 cacaattcca ccttgagtaa tgatgatgaa aactgttaaa catcttctgt gctgtgccat
     2941 tgccgccagc gcattaattt ccaccggggt gcatgctgcg tcctggaaag atgcgctctc
     3001 cagcgccgcc agcgaacttg gcaaccaaaa cagcacgaca caggaaggcg gttggtcgct
     3061 cgcgtcatta actaacttgc ttagcagcgg gaaccaggcc ttaagcgcag ataacatgaa
     3121 caacgccgca ggcattctgc aatactgcgc gaagcaaaag ctggcgtcgg taaccgatgc
     3181 cgaaaacatc aagaaccagg tgctggaaaa gctgggcctg aacagtgaag agcaaaaaga
     3241 agacaccaac tatctggatg gcattcaggg tttgctgaaa accaaagatg gtcagcaact
     3301 caatctggat aacatcggaa cgactccgct ggcagaaaag gtgaaaacca aagcctgcga
     3361 tctggtgtta aagcaggggc tgaacttcat ttcctgaacc gcgaaacgcc gcgttttagc
     3421 tgttacccgg ctgacgcggc tctctcctgc ccttttccct gctcctggac ggttttcccc
     3481 ctgttacacg ggaagcgacc gcgatcaaaa aagtctgttt ataaactaat tcctaacaac
     3541 atcgcatttt tttgacacta gaattgcagc aatatggcga cgccattaca ttgtgcttct
     3601 caaaaagctt aaacgttggc taaacggccc ggtttagtga ggatcgcccg ttgtcagaac
     3661 tactctcttt cgcccttttt ctcgcctctg tgctgattta cgcatggaaa gcgggacgta
     3721 acacctggtg gtttgcagcc acattaacgg tgctggggct atttgtcgtt ttaaatatca
     3781 ccctgtttgc cagcgactat tttactggcg atggtattaa cgacgcggtt ctctatacct
     3841 taaccaacag cctgaccggt gctggcgtca gcaaatacat cctgccgggt atcggcattg
     3901 tgctggggct gacagcggtg ttcggtgcgc tgggctggat cctgcgccgt cgtcgccatc
     3961 atccgcacca ttttggttac agcctgctgg cgctcttact ggcgctgggt tcggtggacg
     4021 ccagcccagc atttcgtcag ataacggaac tggtgaaatc ccagtcacgc gatggcgacc
     4081 cggactttgc ggcttattat aaagagccgt cgaaaactat ccctgacccg aaactcaacc
     4141 tggtttatat ctacggcgaa agtctcgagc ggacctattt tgataacgaa gctttcccgg
     4201 atctcacgcc tgaactgggc gcgttgaaaa atgaaggcct ggatttcagc cacacgcagc
     4261 agctgccagg aacggattac acgattgcgg gcatggtggc ttctcagtgc ggcataccgc
     4321 tgtttgcccc ctttgaaggc aacgcctccg cctctgtctc cagcttcttc ccgcagaaca
     4381 tctgtctggg cgatatcctg aaaaactcgg gttatcagaa ctatttcgtg cagggcgcga
     4441 atctgcgttt tgccggtaaa gatgtgttcc tgaagtcgca tggcttcgac cacttatacg
     4501 gctcagaaga gctgaaaagc gtggtggccg acccgcacta tcgcaacgac tggggattct
     4561 acgacgatac cgttctcgat gaagcgtgga aaaagtttga agagctttcc cgctcaggtc
     4621 agcgattctc actgtttacc ctgacagtcg atacccatca cccggatggt tttatctcgc
     4681 gtacctgtaa ccgcaaaaaa tatgattttg acggtaagcc gaaccagtca ttcagcgcgg
     4741 taagttgcag ccaggagaat atcgcggcgt ttatcaacaa aatcaaagcg tcaccgtggt
     4801 ttaaagatac cgtcatcgtc gtctcttctg accatttagc gatgaacaac acggcgtgga
     4861 aataccttaa taagcaggat cgcaataacc tgttttttgt cattcgtgac gacaagccgc
     4921 agcaagagac gctggcagtg aagcgtaaca cgatggataa cggcgcgacg gtgctggaca
     4981 ttctcggtgg cgataactat ctcggacttg gtcgtagcag tttatccggg cagtcgatgt
     5041 cggaaatctt cctcaatatc aaagagaaaa cattggcgtg gaagccggat atcatccgcc
     5101 tgtggaaatt ccctaaagag atgaaagagt tcactatcga ccagcagaaa aacatgattg
     5161 ccttctcggg tagccatttc cgtttgccgc tgctgttgcg ggtttcagac aagcgcgtag
     5221 aaccgctgcc ggaaagtgaa tactcagcac cgctgcgttt ccagctggcc gatttcgctc
     5281 cacgcgacaa tttcgtctgg gttgaccgtt gctacaagat ggcacaactt tgggctccgg
     5341 aactggcact ctccaccgac tggtgtgtct cgcaggggca gcttggcggt cagcaaattg
     5401 tccagcatgt tgataaaaca atgtggaagg gcaaaacggc atttaaagat acggtcatcg
     5461 acatggcgcg ttacaaaagc aatgtcgata cgctgaaaat tgttgataac gatattcgct
     5521 acaaagccga cagtttcatc ttcaacgtcg ccggtgcgcc agaagaggtg aaacagttta
     5581 gcgggatttc ccgtccggag tcgtggggcc gctggtccaa cgctcagctg ggcgatgaag
     5641 taaaaatcga gtacaagcat ccgctgccga agaaatttga cctggtgatt accgccaaag
     5701 catacggcaa taacgccagc cgtcctattc cggtacgcgt aggcaatgaa gaacaaaccc
     5761 ttgtgctggg caatgaagtg accaccacca cactgcattt cgataaccca accgatgccg
     5821 acacactggt aattgtgccg ccggaacctg tctcaaccaa cgaagggaat atcctcggac
     5881 actcgccgcg taagctcggg atcggcatgg tggaaattaa agtggtggaa cgtgaaggat
     5941 aattcctgac tgatgtgtag gtcgcataag gtgcgaccta cacaccttct gcggcctaca
     6001 aaacatcatt gagaaacaga aaaaaacagc gcccaacact tccccggacg ctgcatggca
     6061 actttaataa tctcgcctta tcagaaagta attacaccct taatcaactc acgattgtta
     6121 atcacatcgc gctcgtaggt ttctgccagc gtggcgaacg gatagcgatg ggttaacatc
     6181 atgtcggcag tgatttttcc ttccgccatc agtcgaccga ctttagcaaa atcttccggc
     6241 gtggcgttgc ggctgcccat catcgtcgtt tcttttttat ggaattccgg atcggagaac
     6301 tgcaactcac ctttaaacag gccgacaaat accaccgtgc cgccgtgacg aatcaaattc
     6361 acggtgttat tcatcgcatg ttgattacct gtcgcgtcga tcactttctg cgccagcgaa
     6421 ccaccaaact gcgcccgtag ctgcgcgtca aaatcttcgg ctgacgggtc cagtaaaggt
     6481 aattccagac gcgttgccac atgttcacgg cgcgccggac tggtatccgc caccaccacc
     6541 tgtgcgccat cggctttagc gattgccgcc gcgcccagac cgattggccc cgccccgacc
     6601 accagcacct gctcgccggg agcaatggct gcgcgacgca ccgcatgagc gctaatagcg
     6661 aaaggttcaa tcaatgctgc cgcctgcggg tcaataccgt ctgcgggcaa aatgttcgcc
     6721 accggcacgc tcaaatactc actaaaaccg ccatcctgat gcacgccaat gactgaaatt
     6781 ttttcacagc aattggtacg cccgctttta cacgccgggc attgctgaca ggcaacataa
     6841 gggatcacag caacttgctg accattttta agatcagcaa tatttttacc cagcccaaca
     6901 atctccccac atatttcatg gcctaaaaca cgtggataac taaaaaatgg ttgatttcca
     6961 ccccaggcat gaatatcggt accgcaaatc ccgacagact taatttttat taatgcttca
     7021 ttgtcacccg gaataggtat ctcgcgttgt ttccagacta attctttcgg ctgctggcaa
     7081 attaaaacat tcatcgtaga catgattcgg ctctccattt tttgttgcct tagatatcaa
     7141 tgaaaatgaa aaatggcagc ggaacggaaa atctgttttg tgaaaacaca cgcataaaaa
     7201 tgttttaaat cgggttttaa tggactcaca aggaggaaaa tatgagtcgt tcacaaaatt
     7261 tacgccacaa tgtgattaac caggtcattg atgatatggc gcggggtcat atcccttccc
     7321 cacttccatc gcaaagtgcg ctggcggaaa tgtacaacat cagccgtact acagtgcgtc
     7381 atattctcag ccacttacgc gaatgcggcg tcttaacgca ggttggaaac gactatgtta
     7441 ttgcgcgtaa acctgaccat gatgacggtt tcgcctgtac taccgcttca atgagtgaac
     7501 aaaacaaagt gtttgagcag gcttttttca cgatgataaa ccagcgccag ttacgcccag
     7561 gggaaacgtt ttctgaactg caactggctc gggccgcggg tgtcagcccg gttctagtaa
     7621 gagaatatct tttaaaattc ggccgttata atcttattca cagcgaaaag cgcggccagt
     7681 ggagcatgaa gcaattcgat caatcctacg ccgagcagct gtttgagcta cgcgaaatgc
     7741 tcgaaacaca ttcacttcag cactttctca acctgcctga tcatgatccc cgctggctgc
     7801 aggcgaaaac catgctcgaa cgtcatcggc tactgcgtga caacatcggc aatagctttc
     7861 gcatgttctc gcaacttgac agagattttc actccttact gctttcagct gccgacaata
     7921 tcttttttga tcaatcgctt gagatcatct cagtcatctt tcattttcac tatcaatggg
     7981 acgaaagcga tcttaaacag cgcaatatca ttgccgtcga tgagcatatg accattctca
     8041 gcgctctgat ttgccgcagt gaccttgatg ccacccttgc gctccgtaac catttgaatt
     8101 cagctaaaca atcaatgatt cgatccatta atgagaacac gcgttatgct cattaagtac
     8161 ggattaaaaa cagcaaacta ttagcgggtg cacggtttta tcaaaagata aataccggga
     8221 aattcccgct tacctatgct cacaatcagt cgactaaaaa tgtttttgtg agcggtagta
     8281 aagtcctaaa actttaacct gccgttaatg tcaaccttgc gtaatgcaca attacgtaaa
     8341 caattaaaat tataaataca ggagtccggc gtggaaaaag aaaatatcac cctcgatcca
     8401 cgttcttcat ttactccatc ttcgtcggca gatattcccg tgccaccaga tggattagtt
     8461 caacgcagta cccgaattaa acgcattcaa accaccgcca tgttgttatt attttttgcg
     8521 gcggtaatca attatctcga ccgcagttcg ctgtcggtag caaatttaac gattcgtgaa
     8581 gaattgggat taagtgccac cgaaatcggc gctttgctct ccgtgttttc actcgcttac
     8641 gggattgcgc aacttccttg cggcccacta ttggatcgta aaggcccacg cctgatgctg
     8701 ggactgggga tgttcttctg gtcactgttc caggcaatgt ctggcatggt gcacaacttt
     8761 acgcagttcg tgttggtgcg tatcggtatg gggattggtg aagcgccgat gaacccatgc
     8821 ggtgtaaaag tcattaacga ctggttcaac atcaaagagc gcggacgccc gatgggcttc
     8881 ttcaacgcag cttctaccat tggcgttgcc gtaagcccac cgattctggc ggcgatgatg
     8941 ctggtgatgg gctggcgcgg gatgtttatt accattggtg tactggggat ttttctcgcc
     9001 atcggctggt atatgctcta tcgcaaccgc gagcacgtag aactgactgc cgttgaacaa
     9061 gcttatctca atgcaggtag cgtcaatgcc cgccgagatc cgctcagttt tgccgaatgg
     9121 cgcagcctgt tccgtaaccg tacaatgtgg ggaatgatgc tcggattcag tggtatcaac
     9181 tacactgcgt ggctgtatct ggcctggctt cctggttacc tgcaaacagc ctataacctg
     9241 gatttaaaaa gcacagggtt gatggcggct atccctttcc tgtttggggc tgccgggatg
     9301 ctggtcaacg gttacgttac tgactggctg gtcaaagggg gaatggctcc gattaaaagc
     9361 cgtaagatct gcattattgc cgggatgttc tgttctgccg cctttacgct ggtcgtacca
     9421 caagcgacaa catccatgac ggcggttctg ctgattggca tggcactgtt ctgtattcac
     9481 tttgccggaa catcctgctg gggcttgatc cacgtcgcag ttgcttctcg catgactgcg
     9541 tcggtgggca gtatccagaa ctttgccagc ttcatctgcg cctcttttgc gccgatcatt
     9601 actggtttta ttgttgatac cacccactca ttccgtctgg cactaatcat ctgcggttgc
     9661 gtcaccgcag cgggggcact ggcgtacatc ttcctggttc gtcagccgat caacgaccca
     9721 cgtaaagatt aatctcctta tgcccgataa cattttgctt atcgggcatt ttcatggcga
     9781 ttaaaatgtt tcccagttct cctcgctatc tgccacggcc attttacgcg gcgcagctgg
     9841 cgtcacggtt tttaccacag ccgatgtttc acgctgctgt tgctgctgtt gctgaatccg
     9901 gaacactgcc acagcttcgg tcaggcgact ggcctgctct tccagcgcgg cggcggcagc
     9961 ggcagattct tccaccagcg cggcgttctg ttgagttacc cggtccatct cagcaaccgc
    10021 taagccaacc tgatcgatac cacggctctg ctcatcagaa gcagaagcaa tttcgcccat
    10081 aatgtccgtc acgcgggtca cggcgctgac aatctccgcc attgtttccc cggcgctttc
    10141 gaccagcgta gagccaacat ccactttccc caccgagtct tcaataaggc ttttaatttc
    10201 acgagccgcc tgagcgctac gctgggccag attacgcact tctcccgcaa ccaccgcaaa
    10261 accgcgccct tgctcacccg cacgcgctgc ttcaaccgcc gcgttcaaag ccagaatatt
    10321 ggtctggaag gcaatgccgt caattacgct gataatatcg gcgattttct gcgaactggt
    10381 ggagatatcg cgcatagtct gcaccacgtt atctaccact ttgccgcccc gttgcgccgt
    10441 ttcagaagca cttaatgcca gatggctggc ctggcgcgca ttctcggcgt tctgtttcac
    10501 cgttgcggtc agttgctcca tgctggctgc cgtctcttcc agcgaagcgg cctgttgctc
    10561 ggtgcgcgaa gagagatcgt tattgccggt agcgatttcg ctggcaccgc tatagatggc
    10621 attggccccg ttgcgcacat caccgacggt acgcatcagc tctccctgca tatggcgcaa
    10681 actctctgcc agttgcccca tctcattaga gccatccacc tcaatcggtt tcaccagatc
    10741 gccgcctgca atatgacgga tgctgtcaat caggcgattc attggcgcta ccagcgaggc
    10801 tttaataccg aaccagacgg cgaagatgac cgccagtacg acgatcatca cgcccaccag
    10861 aatccacatc gcctggctgt aggaggcatt gttatcgctg acggcgatat catagagccg
    10921 atcgttttgc tccatgtaag ccacatactg cttctcgaaa ccgtcttgat atccctgggt
    10981 cggctgatca aagaactcgt tgattttgcc tgcacctaac agttggatca gctccgccag
    11041 cgcattgtga taaatatcgt aattacgttt gatctctgcc gctgcggcgg tgctctgacg
    11101 cgggtcacgc ggcaacgctt cgtaatccgc ccagtttttt tccgcctgtt tcagcgaaat
    11161 actggcactc tgcatcagct cagcaacggt tgaaccgcta ccaatattat tctgatccat
    11221 catgtagcgg atacccgcgc ggttgagggt gttacgcgtc tgcaacaacg cgacccagct
    11281 gccattcagc gtggattgct gctggcgaat ggtttgtaaa acagtgaaat tttctttgtc
    11341 attctttaag gcattaaaga acagaccgcc tgatgtcagt tgtaaaaggc caaaaacggc
    11401 caaaaccagc agtaagctgg tcacgatctt gatacgtttt aacatggttt ctctttcctg
    11461 tggaccgatg caagattttc ggcctggaaa gcaaaaactt tatgaaaagg tgtaacccgc
    11521 catccatgga aaaaccaggc gctggttatc agatactaaa aagttattca ttatcgcccg
    11581 ggatggcttc ttgtcgggaa ttgcccagag caataaattc ctctaacaga tgggttaact
    11641 gttgcatttt ctcggcagta aactgagctt caatctgccg ataggcttct tcaatctgtg
    11701 tctgagcgcg gttatacagc gcctgcccct ctttggttag cgagatatag agcttccgct
    11761 gatcattgat cggctttaat cgcaacacta aaccgtcgcg ttccatccgc gtaaggatcc
    11821 cggtcaggct tgggcgcaaa atgcatgcgc gatacgccag atcgtgaaaa tccattgatg
    11881 ggctttccgc cagaatacgc acgatgcgcc actgttgctc agtcaaatta tgccgtttaa
    11941 cgattgggcg aaaataactc atcgccgctt ctcgcgcctg gagcaacgca atggttagag
    12001 agtcgtgcat tatctttccc ctgaaaaatt caaaatcatt aatatagaaa cagttaatca
    12061 tcacgttacc gggactgcgc tgcccctgca attcttcatt ttatcaaaat tgagcatgtt
    12121 ttgttaactt gctg
//
LOCUS       DAPGUL010000132        11862 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.135, whole genome shotgun sequence.
ACCESSION   DAPGUL010000132 DAPGUL010000000
VERSION     DAPGUL010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11862)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11862)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11862
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.135"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            275..1663
                     /gene="narU"
                     /locus_tag="RHX21_003942"
     CDS             275..1663
                     /gene="narU"
                     /locus_tag="RHX21_003942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite transporter NarU"
                     /protein_id="HDV1989063.1"
                     /translation="MALQNEKNSRYLLRDWKPENPAFWENKGKHIARRNLWISVSCLL
                     LAFCVWMLFSAVTVNLNKIGFNFTTDQLFLLTALPSVSGALLRVPYSFMVPIFGGRRW
                     TVFSTAILIIPCVWLGIAVQNPNTPFGIFIVIALLCGFAGANFASSMGNISFFFPKAK
                     QGSALGINGGLGNLGVSVMQLVAPLVIFVPVFAFLGVNGVPQADGSVMSLANAAWIWV
                     PLLAIATIAAWSGMNDIASSRASIADQLPVLQRLHLWLLSLLYLATFGSFIGFSAGFA
                     MLAKTQFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTLINFIFMAIFSALLF
                     LTLPGTGSGNFIAFYAVFMGLFLTAGLGSGSTFQMIAVIFRQITIYRVKMKGGSDEQA
                     QKEAVTETAAALGFISAIGAVGGFFIPQAFGMSLNMTGSPVGAMKVFLIFYIVCVLLT
                     WLVYGRRKFSQK"
     gene            1745..5485
                     /gene="narZ"
                     /locus_tag="RHX21_003943"
     CDS             1745..5485
                     /gene="narZ"
                     /locus_tag="RHX21_003943"
                     /EC_number="1.7.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase Z subunit alpha"
                     /protein_id="HDV1989064.1"
                     /translation="MSKLLDRFRYFKQKGETFADGHGQVMHSNRDWEDSYRQRWQFDK
                     IVRSTHGVNCTGSCSWKIYVKNGLVTWEIQQTDYPRTRPDLPNHEPRGCPRGASYSWY
                     LYSANRLKYPLIRKRLIELWREALKQHSDPVLAWASIMNDPQKCLSYKQVRGRGGFIR
                     SNWQELNQLIAAANVWTIKTYGPDRVAGFSPIPAMSMVSYAAGTRYLSLLGGTCLSFY
                     DWYCDLPPASPMTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGT
                     KTIAITPDYSEVAKLCDQWLAPKQGTDSALAMAMGHVILKEFHLDNPSDYFINYCRRY
                     SDMPMLVMLEPRDDGSYVPGRMIRASDLVDGLGESNNPQWKTVAVNTAGELVVPNGAI
                     GFRWGEKGKWNLESIAAGTETELSLTLLGQHDAVAGVAFPYFGGIENPHFRSVKHNPV
                     LVRQLPVKNLTLVDGNTCPVVSVYDLVLANYGLDRGLEDENSAKDYAEIKPYTPAWGE
                     QITGVPRQYIESIAREFADTAHKTHGRSMIILGAGVNHWYHMDMNYRGMINMLIFCGC
                     VGQSGGGWAHYVGQEKLRPQTGWLPLAFALDWNRPPRQMNSTSFFYNHSSQWRYEKVS
                     AQELLSPLADASKYSGHLIDFNVRAERMGWLPSAPQLGRNPLGIKAEADKAGLSPTEF
                     TAQALKSGDLRMACEQPDSGSNHPRNLFVWRSNLLGSSGKGHEYMQKYLLGTESGIQG
                     EELGASDGIKPEEVEWQTAAIEGKLDLLVTLDFRMSSTCLFSDIVLPTATWYEKDDMN
                     TSDMHPFIHPLSAAVDPAWESRSDWEIYKGIAKAFSQVCVGHLGKETDVVLQPLLHDS
                     PAELSQPCEVLDWRKGECDLIPGKTAPNIVAVERDYPATYERFTSLGPLMDKLGNGGK
                     GISWNTQDEIDFLGKLNYTKRDGPAQGRPLIDTAIDASEVILALAPETNGHVAVKAWQ
                     ALGEITGREHTHLALHKEDEKIRFRDIQAQPRKIISSPTWSGLESDHVSYNAGYTNVH
                     ELIPWRTLSGRQQLYQDHPWMRAFGESLVAYRPPIDTRSVSEMRQIPPNGFPEKALNF
                     LTPHQKWGIHSTYSENLLMLTLSRGGPIVWISETDARELTIVDNDWVEVFNANGALTA
                     RAVVSQRVPPGMTMMYHAQERIMNIPGSEVTGMRGGIHNSVTRVCPKPTHMIGGYAQL
                     AWGFNYYGTVGSNRDEFIMIRKMKNVNWLDDEGRDQVQEAKK"
     gene            5482..7026
                     /gene="narH"
                     /locus_tag="RHX21_003944"
     CDS             5482..7026
                     /gene="narH"
                     /locus_tag="RHX21_003944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HDV1989065.1"
                     /translation="MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTGREGMEYAWFNNV
                     ETKPGIGYPKNWEDQEEWQGGWVRDVNGKIRPRLGSKMGVITKIFANPVVPQIDDYYE
                     PFTFDYEHLHSAPEGKHIPTARPRSLIDGKRMDKVIWGPNWEELLGGEFEKRARDRNF
                     EAMQKEMYGQFENTFMMYLPRLCEHCLNPSCVATCPSGAIYKREEDGIVLIDQDKCRG
                     WRLCISGCPYKKIYFNWKSGKSEKCIFCYPRIESGQPTVCSETCVGRIRYLGVLLYDA
                     DRIEEAASTEREVDLYERQCEVFLDPHDPSVIEEALKQGIPQNVIEAAQRSPVYKMAM
                     DWKLALPLHPEYRTLPMVWYVPPLSPIQSYADAGGLPKSEGVLPAIESLRIPVQYLAN
                     MLSAGDTGPVLRALKRMMAMRHYMRSQTVEGVTDTRAIDEVGLSVAQVEEMYRYLAIA
                     NYEDRFVIPTSHREMAGDAFAERNGCGFTFGDGCHGSDSKFNLFNSSRIDAINITEVR
                     DKAEGE"
     gene            7026..7721
                     /gene="narW"
                     /locus_tag="RHX21_003945"
     CDS             7026..7721
                     /gene="narW"
                     /locus_tag="RHX21_003945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HDV1989066.1"
                     /translation="MQILKVIGLLMEYPDELLWECKEDALALIRSDAPMLTDFTHNLL
                     NAPLLDKQAEWCEVFDRGRTTSLLLFEHVHAESRDRGQAMVDLLAEYEKVGLQLDCRE
                     LPDYLPLYLEYLSVLPDDQAKEGLLNVAPILALLGGRLKQREAPWYALFDALLQLAGS
                     SLSSDSVTKQVNSEERDDTRQALDAVWEEEQVKFIEDNATACDSSPLNQYQRRFSQDV
                     APQYVDISAGGGK"
     gene            7718..8398
                     /gene="narI"
                     /locus_tag="RHX21_003946"
     CDS             7718..8398
                     /gene="narI"
                     /locus_tag="RHX21_003946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase subunit gamma"
                     /protein_id="HDV1989067.1"
                     /translation="MIQYLNVFFYDIYPYICATVFFLGSWLRYDYGQYTWRASSSQML
                     DKRGMVIWSNLFHIGILGIFFGHLFGMLTPHWMYAWFLPVAAKQLMAMVLGGICGVLT
                     LIGGAGLLWRRLTNQRVRATSTTPDIIIMSILLIQCLLGLSTIPFSAQYPDGSEMMKL
                     VGWAQSIVTFRGGSSEMLNGVAFVFRLHLVLGMTIFLLFPFTRLVHVWSAPFEYFTRR
                     YQIVRSRR"
     gene            8477..9370
                     /locus_tag="RHX21_003947"
     CDS             8477..9370
                     /locus_tag="RHX21_003947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
                     /protein_id="HDV1989068.1"
                     /translation="MKPQVYHVDAFTSQPFRGNSAGVVFPADNLSEAQMQLIARELGH
                     SETAFLLHSDDSDVRIRYFTPTVEVPICGHATVAAHYVRAKVLGLGNCTIWQTSLAGK
                     HRVTIEKHNDDYRISLEQGTPGFEPPLEGETREAIINALHLTEDDILPGLPIQVATTG
                     HSKVMIPLKPEVDIDALSPDLAALSAISKQIGCNGFFPFQIRPGKNETDGRMFSPAIG
                     IVEDPVTGNANGPMGAWLVHHNVLPHDGKVLRVKGHQGRALGRDGVIEVTVTIRDNQP
                     EKVTISGTAVILFHAEWAIEI"
     gene            complement(9466..10311)
                     /gene="nhoA"
                     /locus_tag="RHX21_003948"
     CDS             complement(9466..10311)
                     /gene="nhoA"
                     /locus_tag="RHX21_003948"
                     /EC_number="2.3.1.118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-hydroxyarylamine O-acetyltransferase"
                     /protein_id="HDV1989069.1"
                     /translation="MTPILNHYFARINWSGAAAVNIDTLRALHLKHNCTIPFENLDVL
                     LPREIQLDDQSLEEKLVIARRGGYCFEQNGVFERVLRELEFNVRSLLGRVVLSNPPAL
                     PPRTHRLLLVELEEEKWIADVGFGGQTLTAPIRLVSDLVQTTPHGEYRLLQEGDDWVL
                     QFNHHQHWQSMYRFDLCEQQQSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLT
                     NFHFTHYENGHAVEQRNLPDVVSLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTH
                     PEAGK"
     gene            10484..11053
                     /locus_tag="RHX21_003949"
     CDS             10484..11053
                     /locus_tag="RHX21_003949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415979.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HDV1989070.1"
                     /translation="MSRFIPIELHHASRLLNHGPTVMITSFDEQSQRRNIMAAAWSMP
                     VEFEPPRVAIVVDKSTWTRELIERNGKFGIVIPGVAATNWTWAVGSVSGREEDKFNCY
                     GIPVVKGPVLGLPLVEEKCLAWMECRLLPATSAQQKYDTLFGEVVSAAADARVFVEGR
                     WQFDDDKLNTLHHLGAGTFVTSGKRVTAG"
     gene            complement(11057..11284)
                     /gene="pptA"
                     /locus_tag="RHX21_003950"
     CDS             complement(11057..11284)
                     /gene="pptA"
                     /locus_tag="RHX21_003950"
                     /EC_number="5.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tautomerase PptA"
                     /protein_id="HDV1989071.1"
                     /translation="MPHIDIKCFPRELDEQQKAALAADITDVIIRHLNSKDSSISIAL
                     QQIQPESWQAIWDAEIAPQMEALIKKPGYSM"
     gene            complement(11338..11862)
                     /locus_tag="RHX21_003951"
                     /pseudo
     CDS             complement(11338..11862)
                     /locus_tag="RHX21_003951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
BASE COUNT         2805 a         3076 c         3086 g         2895 t
ORIGIN      
        1 agttaatatg taacccttta gattcacgat ctgaagggtt gaaacatgac atacgttcaa
       61 agattaaccc ccgtttgaag gttagcttgt tagttacatt tagtaacaca tatctggcta
      121 cttaatcccc attctgcccc cgcggttacg ctttcttatc tattctttca atcagcactt
      181 cacccaattc atccttaatt ctaataactg gctattgcgc cttacctcct gttttgtctt
      241 ttttcattac caatgtgtgc atgtgaggaa caatatggca ctgcaaaatg agaaaaatag
      301 tcgttatctt ttacgcgact ggaaaccaga aaatccggcc ttctgggaaa ataaaggaaa
      361 acatattgct cgaagaaacc tctggatatc agtcagttgt ctacttcttg ccttctgtgt
      421 ctggatgcta tttagcgcag ttaccgttaa tctcaataaa atcggtttta attttactac
      481 cgatcaactc tttttattaa ccgcattacc ctccgtttct ggcgcattat tgcgtgttcc
      541 ctactccttt atggtgccta tattcggtgg acgccgatgg acggttttta gtactgcaat
      601 cctgattatt ccttgcgtct ggctcggaat tgccgtgcaa aatccgaata ctccttttgg
      661 gatatttatc gttatcgctt tgctatgcgg ttttgcaggt gcaaactttg cttcgagcat
      721 gggcaatatc agtttcttct ttccaaaagc caaacaaggg agcgctcttg ggattaatgg
      781 cggattagga aacttaggtg taagtgtaat gcagctggtt gcaccgctgg tcatttttgt
      841 acctgtattt gcctttctcg gcgtcaatgg cgtaccgcag gccgacggtt cggtgatgtc
      901 gctggcgaat gccgcatgga tttgggtacc gctactggcg attgccacga tcgccgcctg
      961 gtcagggatg aatgatatcg ccagttcacg cgcctcaatt gccgaccagc tccctgtctt
     1021 acaacgcctg catctctggc tgctgagcct gctttacctt gccaccttcg gttcgtttat
     1081 cggtttttct gcgggttttg ccatgctggc aaaaacccag ttcccggatg tgaatattct
     1141 gcgcctggcg ttctttggcc catttatcgg tgccatcgcg cggtcggttg gtggtgctat
     1201 ttccgataag ttcggcggcg tgcgggtgac gttgatcaac tttattttta tggcgatttt
     1261 cagtgccctg ctgttcctta ccttaccggg cacaggctcc ggtaatttca tcgcctttta
     1321 cgccgtattt atggggctgt ttctgactgc gggtctggga agtggttcta ctttccagat
     1381 gatcgccgtc atctttcgcc agataaccat ttatcgggta aagatgaaag gcggtagtga
     1441 tgagcaagct cagaaagaag ccgtcaccga aacggcggcg gctctgggct ttatctcagc
     1501 cattggcgca gtgggcggct tttttattcc gcaggcgttt ggcatgtcgc tcaatatgac
     1561 cggctctccg gtcggcgcga tgaaagtgtt tttaatcttc tacatcgttt gtgtgctgct
     1621 gacctggctg gtttatggtc ggcggaagtt cagccaaaaa taagagatcg atgcctgatg
     1681 tacaaccgtg tcgcatccga caaggcatca gatcccaatt cattcctgga gcaggagtca
     1741 tgtcatgagt aaacttttgg atcgctttcg ctacttcaaa caaaagggcg aaacctttgc
     1801 cgatggtcac ggacaggtga tgcatagcaa ccgcgactgg gaggacagct atcgccagcg
     1861 ttggcagttc gacaaaatcg tgcgttccac ccacggtgtt aactgtacag gctcctgtag
     1921 ctggaaaatc tacgttaaaa atggtctggt gacctgggaa atccaacaga ccgactaccc
     1981 gcgcactcgc cctgacctgc ccaatcatga acctcgcggc tgcccgcgtg gcgcaagtta
     2041 ctcctggtat ctttacagcg ctaaccgcct gaaatacccg ctcattcgta aacgactgat
     2101 tgaactgtgg cgcgaagccc tcaagcaaca cagcgatccg gtactggcgt gggcatcgat
     2161 tatgaacgat ccgcaaaagt gcctgagcta caaacaagtg cgtgggcgcg gcgggtttat
     2221 ccgctccaac tggcaggaac taaaccagct gattgccgcc gctaacgtct ggaccatcaa
     2281 aacctacggc ccggatcgcg ttgccggttt ctcgccgatc ccggcgatgt cgatggtttc
     2341 ttacgccgcc ggaacgcgtt atctgtcact gcttggcggc acctgtttaa gcttctacga
     2401 ctggtattgc gacctgccgc ccgcctcgcc gatgacctgg ggcgagcaaa ccgacgtacc
     2461 ggaatctgcc gactggtata actccagcta catcatcgcc tgggggtcta acgtaccgca
     2521 gacacgtacg ccggacgccc acttctttac cgaagtacgc tacaaaggca ctaaaaccat
     2581 cgccattacc cctgactact ctgaagtggc caaattgtgc gaccagtggc tggcaccgaa
     2641 acaaggcact gatagcgccc tggcgatggc aatgggccat gtgattttaa aagagtttca
     2701 tctcgataat cccagcgact actttatcaa ctactgccgc cgctacagcg acatgccgat
     2761 gctggtaatg ctggagcctc gcgacgatgg tagctacgtt cccgggcgca tgatccgcgc
     2821 atctgacctg gtggatggac tgggcgaaag caacaatccg cagtggaaaa ccgtagcagt
     2881 taataccgca ggtgaattgg tagtgccgaa cggtgcgatt ggtttccgct ggggagaaaa
     2941 aggcaaatgg aatctggaat ccattgccgc cggtacggaa accgaattgt cgttaaccct
     3001 gctcggtcaa catgacgctg ttgcaggcgt ggccttcccc tactttggcg gcattgaaaa
     3061 tccgcatttt cgcagcgtaa aacacaatcc ggtgctggtg cgccaattgc ccgttaaaaa
     3121 cctgacgtta gtcgatggca acacctgtcc ggtggtcagc gtttatgatt tggtactggc
     3181 gaattacggc ctcgatcgcg ggctggaaga tgaaaacagt gcgaaagatt acgctgaaat
     3241 caaaccgtac accccagcct ggggtgagca aattaccggc gtgccgcgcc agtatattga
     3301 atccatcgct cgtgaatttg ccgatactgc ccataaaacg catgggcgct caatgattat
     3361 cctcggcgct ggcgtcaacc actggtatca catggatatg aactaccgtg ggatgatcaa
     3421 tatgctgatc ttctgcggtt gtgtcgggca aagcggtggc ggctgggcac actatgtcgg
     3481 ccaggaaaaa ctgcgcccac aaaccggctg gttgccactg gcctttgcgc tcgactggaa
     3541 ccgaccaccg cgccaaatga acagcacctc gtttttctac aatcattcca gccaatggcg
     3601 ctatgaaaaa gtctctgctc aggagttact ttcaccgctc gccgatgcca gtaagtacag
     3661 cggtcatctg attgatttca acgttcgcgc cgaacgtatg ggctggctac cttctgcgcc
     3721 gcagctgggg cgtaacccgc tcgggattaa agctgaagcc gacaaggccg gattatcccc
     3781 cacagaattt accgcccagg cgctgaaatc gggcgattta cgtatggcct gcgaacaacc
     3841 agatagcggc agcaatcatc cgcgtaattt gtttgtctgg cgctctaacc tgcttggctc
     3901 ctccggcaaa ggccacgagt atatgcagaa gtatctgctg gggaccgaaa gcgggattca
     3961 gggcgaggaa ctcggtgcca gcgacgggat caaaccggaa gaagtcgagt ggcaaactgc
     4021 ggcgattgaa ggcaagctcg acctgctggt gacgctcgac ttccgcatgt ccagtacctg
     4081 cctgttctcc gatatcgttc tgcccaccgc cacctggtac gaaaaagacg atatgaacac
     4141 ctcggatatg catccgttta ttcatccgct ttctgcggcg gtcgatccgg cgtgggaatc
     4201 acgcagcgac tgggaaatct acaaaggtat cgccaaagca ttttcgcaag tgtgcgtggg
     4261 tcatcttggc aaagaaaccg acgtggtatt acaaccccta ctgcatgact ctccggcaga
     4321 gctctcacag ccgtgtgaag tgctcgactg gcgcaaaggc gaatgcgatc tgattccagg
     4381 caaaaccgcg ccgaatattg tggcggtgga gcgcgactac cctgctacgt atgaacgctt
     4441 tacctcgctc gggccattga tggacaaact tggcaatggc ggtaaaggga tttcgtggaa
     4501 tacccaggat gaaatcgatt tcctcggcaa actcaattac accaagcgtg atggcccggc
     4561 acaggggcgt ccgctgattg acaccgccat tgacgcttca gaagtgattc tggcactggc
     4621 accggaaacc aacggtcatg ttgcagtcaa agcgtggcag gcgctgggcg agatcaccgg
     4681 gcgcgaacat acccatctgg cgctgcacaa agaggacgag aagattcgct ttcgcgatat
     4741 tcaggcgcag ccgcgtaaaa ttatctccag ccccacctgg tccggtctgg aaagcgatca
     4801 cgtatcctat aacgcgggat acaccaacgt tcatgagtta attccgtggc gcacgctgtc
     4861 gggacgccag cagctctatc aggatcatcc gtggatgcgt gcttttggtg aaagcctggt
     4921 ggcttatcgc ccgcctatcg acacccgtag cgtcagtgag atgcgccaga taccgccaaa
     4981 cggcttcccg gaaaaagcac ttaacttcct gacgccgcac cagaaatggg gcattcactc
     5041 aacctacagt gaaaacctgc taatgctgac gctctctcgc ggtggaccga ttgtctggat
     5101 cagcgaaaca gatgcccgag aactgaccat tgtcgataac gactgggtgg aagtattcaa
     5161 cgccaacggc gcgctgactg cccgcgcggt ggtcagccaa cgtgtaccgc cgggcatgac
     5221 catgatgtat cacgcccagg aacgcattat gaatattcct ggttcggaag taactggcat
     5281 gcgcggcggc attcataact cggtcacccg cgtttgcccg aaaccaacgc atatgattgg
     5341 cggttacgcg cagctggcct ggggctttaa ctactacggc accgtcggat cgaaccgcga
     5401 tgagttcatc atgatccgca agatgaagaa cgttaactgg ctggatgatg aaggtcgcga
     5461 tcaggtacag gaggcgaaaa aatgaaaatc cgttcacaag tcggcatggt gcttaacctc
     5521 gacaaatgta tcggctgcca tacctgttcg gtgacctgta aaaacgtctg gaccgggcgc
     5581 gaaggcatgg agtacgcatg gtttaacaac gtcgaaacca aaccgggcat tggttatccg
     5641 aaaaactggg aagatcagga agagtggcaa ggcggctggg tccgcgatgt gaatggcaag
     5701 atccgtccgc gtctgggcag caagatgggc gtaataacca aaatcttcgc caacccggtg
     5761 gtgccgcaga ttgatgatta ctacgaacct ttcaccttcg actacgaaca tttgcatagc
     5821 gcaccggaag gcaaacatat ccctactgct cgcccgcgtt cactgattga cggcaaacgg
     5881 atggacaaag tgatctgggg cccaaactgg gaagaactgc tgggcggcga gtttgaaaaa
     5941 cgtgcccgcg accgcaactt cgaggccatg caaaaggaga tgtacgggca gtttgaaaac
     6001 accttcatga tgtacctgcc gcgcctgtgc gaacactgcc tcaatcccag ttgcgtggcg
     6061 acctgcccaa gcggcgctat ctacaaacgc gaagaagacg gcattgtgct gattgatcag
     6121 gataaatgcc gtggctggcg tttgtgcatt agcggttgtc cgtacaaaaa aatctacttc
     6181 aactggaaaa gcggcaagtc agaaaaatgt atcttctgtt atccgcgaat tgagtcaggc
     6241 caacccaccg tgtgctcaga aacctgcgtg ggtcgcatcc ggtatctggg cgtgctgctt
     6301 tacgacgccg accgcattga ggaagcggcg agcaccgagc gcgaagttga cctctatgaa
     6361 cgtcagtgcg aagtattcct cgatccacac gatccctcag tgatcgagga agccctgaaa
     6421 caaggtattc cacaaaacgt gattgaagct gcccagcgtt cgcctgtcta caaaatggcg
     6481 atggactgga aactggcgct accgctgcac cctgaatatc gcaccctgcc aatggtctgg
     6541 tacgttcctc cgctgtcgcc gattcagtcc tacgcagatg cgggcggttt gccgaaaagc
     6601 gaaggcgtgc tgcccgccat cgaaagcctg cgtattccgg tgcaatatct cgccaatatg
     6661 ttgagtgccg gcgataccgg tccggtactg cgggcgctga aacggatgat ggcgatgcgc
     6721 cactatatgc gttcacaaac cgtggaaggc gttactgata ctcgtgccat cgacgaagta
     6781 ggcctgagcg tcgcccaggt cgaagagatg tatcgttacc tcgccattgc caactatgaa
     6841 gatcgttttg tcatcccgac gagccatcgg gaaatggcgg gcgatgcctt cgcagaacgc
     6901 aacggctgcg gttttacctt tggcgacggt tgccacggtt cggacagtaa attcaacctg
     6961 ttcaacagta gccgtatcga tgccatcaac atcaccgaag tgcgcgacaa agcggagggc
     7021 gaataatgca gatcctcaaa gtgatcggcc tgttgatgga gtatccggac gagctgttgt
     7081 gggaatgcaa ggaggacgcg ctggcgttga tccgcagcga cgcgccgatg cttacggatt
     7141 tcacccacaa cctgcttaac gcaccgctgc tggataaaca ggccgaatgg tgcgaagtgt
     7201 ttgaccgtgg acgtaccaca tcgctgctgc tgttcgaaca tgttcatgcc gagtcccgcg
     7261 atcgcggcca ggcaatggtg gacctgctgg cggagtatga aaaggtcggc ctgcagctgg
     7321 attgtcggga actgcccgat tatctaccgc tgtatctgga gtatttaagc gtactgcctg
     7381 acgatcaggc gaaagaagga ttgctcaatg ttgcgccgat cctcgccctg cttggcggtc
     7441 gcttaaaaca acgcgaggca ccgtggtacg cgttgtttga tgctctgctg caactggcgg
     7501 gaagctccct ttcaagtgac agtgtcacaa aacaagtaaa cagcgaagag cgcgatgaca
     7561 cccgccaggc gcttgatgca gtgtgggaag aggaacaggt gaagtttatt gaagataacg
     7621 ccacggcgtg tgacagctcg ccgcttaatc aatatcagcg acgctttagc caggatgtcg
     7681 cgccgcaata tgtcgacatc agtgcgggag gtgggaaatg attcagtatc tgaacgtctt
     7741 tttttacgat atctacccgt acatttgtgc gacggtgttt ttcctcggca gctggctgcg
     7801 ctacgactac gggcagtaca cctggcgcgc ctcctcaagt caaatgctcg ataaacgcgg
     7861 gatggtgata tggtcgaatc tgttccatat cggcattttg gggattttct tcgggcactt
     7921 gttcggcatg ttaacgccgc actggatgta cgcgtggttt ttgccagtgg cagcgaaaca
     7981 actaatggcg atggtgctcg gcggtatttg cggtgtgttg acattgattg gcggcgcagg
     8041 actgctgtgg cgcaggctga caaatcagcg cgtgcgtgca acttccacta cgccggatat
     8101 tatcatcatg agcattttgc tgatccagtg tctgctgggg ctaagtacca taccgttttc
     8161 agcacagtat cctgatggta gcgaaatgat gaagctggtg ggttgggcgc aaagcattgt
     8221 cactttccgt ggtggatcgt cagaaatgct taacggcgta gcgttcgttt tccgcctgca
     8281 tctggtattg ggaatgacca tcttcctgct cttcccgttc accagattgg tgcatgtgtg
     8341 gagcgcgccg tttgagtact ttactcgtcg gtatcagatt gtgcgttcgc ggcgataatt
     8401 tcaccctggc cggatagccc ttcgctctcc ggccacttgc aggctatgat agttctccag
     8461 tcacaggaga acgttaatga aaccgcaggt gtaccacgtc gatgctttta cctctcaacc
     8521 atttcgcggc aattctgccg gtgttgtttt ccccgccgat aatcttagcg aagcgcaaat
     8581 gcagcttatc gcccgcgagt taggccattc ggaaactgct tttctgctgc acagcgacga
     8641 cagcgatgtg cgcatccgct actttacgcc aacggttgaa gtgccgattt gcggtcacgc
     8701 gacagtagct gcgcactatg tacgtgcgaa ggtgttaggt ttaggaaatt gcacgatctg
     8761 gcaaacatcg ctggcaggaa aacatcgcgt gactatcgaa aagcacaacg atgattatcg
     8821 tatttcgctg gaacaaggta cgccgggctt tgaaccgccg ctggagggtg aaacacgtga
     8881 ggcgattatc aacgcgcttc atctcactga ggacgatatt ctgccaggct tgccaattca
     8941 ggtggcaaca acaggacact caaaagtgat gatcccgttg aaaccagaag tggatatcga
     9001 cgccctttcg cctgatcttg ctgcgctgag cgctatcagc aaacagattg gctgcaatgg
     9061 tttcttcccg ttccagatcc gcccaggcaa aaacgaaacc gatggtcgca tgttctcgcc
     9121 tgcgattggt attgtggaag atccggtgac tggcaatgcc aatggcccga tgggtgcatg
     9181 gttggtacat cacaacgtat tgccccacga tggcaaggtg ctgcgtgtta aaggccatca
     9241 ggggcgcgca ttggggcgtg acggcgtgat tgaagtgacg gtgacaattc gtgataacca
     9301 accggaaaaa gtcaccattt caggtacagc ggtgattttg tttcatgccg aatgggcaat
     9361 tgaaatctga aatcgttgcc tgatgcgctt cgcctgtcag gtctacaacc gggctaatgt
     9421 atgccggata aggcgtttac gccgcatccg gcaacctgac ataaattatt ttcccgcctc
     9481 cggatgcgta tcaaacgccg ccatcaccag cgctaactca tccacagtaa agccatgttt
     9541 cgcatcatcc acgcccagac caaactgttc ctgcatcacg gcatataacg acaccacatc
     9601 cggtagattt cgctgctcca ccgcgtgccc attttcataa tgggtaaaat gaaaattggt
     9661 cagcgttagc ttgccaccgt ccggcaaatg gcggcacatc agcaaatgat ggcgaaaatg
     9721 cgactgcggc cagtgcgccg accagaaatt gcccatcaca taatcgcttt gttgctgctc
     9781 gcagagatca aaacggtaca tcgactgcca atgctgatga tgattaaact gcaacaccca
     9841 atcatcaccc tcctgcaaca accgatactc tccgtgtggc gtggtctgca cgagatcgga
     9901 aactaaacga atcggcgcgg ttagcgtctg cccaccgaaa ccgacatcag caatccattt
     9961 ttcctcttcc agttccacca acagcaaacg atgggtgcgc ggcggtaatg ctggcggatt
    10021 tgataacact acgcgcccta acaagctgcg aacgttaaac tccagctcgc gtaacacccg
    10081 ctcaaacacg ccattctgct caaaacagta accgccacga cgggctatca ccagtttctc
    10141 ttccagcgat tgatcatcaa gctgtatttc cctcggcagc aaaacgtcga ggttttcaaa
    10201 cggaatagtg caattgtgtt tcaggtgcaa tgcacgaagc gtatcaatat tgaccgcagc
    10261 agctcccgac cagttaatac gggcaaaata gtgattcaga atgggcgtca tcaggcgttt
    10321 cccttagtgg ttttctcaac ttataacctg gaatagacgc cgcaccggct attttgtgcg
    10381 atcgcggaca tgcatcacgt ttgcaaatcg ccaatcccgt taatttcgtt acttattgcg
    10441 ttacggacta cgcttaaaaa aaccttcttc gcgaggcgat accatgagcc gattcatccc
    10501 catagaatta caccatgcca gccgtctgtt aaatcatggc ccaactgtca tgatcaccag
    10561 tttcgatgag caatcccagc ggcgtaacat tatggcagca gcctggtcaa tgccggtgga
    10621 gtttgaaccg ccacgcgtgg cgattgtggt agataaatcg acatggacca gggagttgat
    10681 tgaacgtaac ggtaaatttg gcatcgttat cccgggcgtt gcagcaacta actggacgtg
    10741 ggcagtggga agcgtgtcgg gtcgtgaaga agataaattt aattgctatg gcattccggt
    10801 ggtgaaaggt ccggtgcttg gtttgccact tgttgaagag aaatgcctgg cgtggatgga
    10861 gtgccgcctg ctacctgcga cttctgcgca acaaaaatac gacacgctgt ttggcgaggt
    10921 ggtatcagca gcggcagacg cacgggtatt tgtcgaaggc cgctggcagt ttgatgatga
    10981 taagctcaat acgttgcatc atttaggtgc tggcacgttt gttactagcg gcaagcgtgt
    11041 tacggcaggt taagcattac atgctgtaac cgggtttctt tatcaaagcc tccatttggg
    11101 gcgcgatttc ggcatcccag atagcttgcc aagattctgg ttgaatctgc tgtagagcaa
    11161 tgcttatcga actgtcttta ctgttcagat ggcgaataat aacgtcggta atatctgcag
    11221 caagtgctgc tttttgttgt tcgtccagtt cacgcggaaa gcatttaatg tcgatgtgcg
    11281 gcatgattgt gctccttttg aaagatgtca gtaaaattaa cacacattgt gaattttcag
    11341 tcctttccat tcaaacgtga aatcaataag ttcatcaggg acatcgcaaa caatatgaat
    11401 acggatttct tctctgccgt gactcttttc acaaattgcg taactgtcat gctctggatt
    11461 atttaattct ttcagcggaa atttttcctc aaaggcttta tttagccacc cctggtttcc
    11521 tttcaccgcg aataaataat cacctccctg tttttgtatc ttctctgcta tatctttctg
    11581 gcaacccatc gcatcagttg tgatgatttt tcctttaata tccagcatgt taagaagttc
    11641 tgggatagct gtaatctcat tagatttatc atccgtcttg atctgtccga tgaccagact
    11701 gtgcattgtt gagaacgcac taatgacatg aatcgctccc ctgcggcgac tcttatcata
    11761 agaatgccgg agcgtttttc catcaattgc aatgacgtct ttatcatctg aagaatgaca
    11821 atcacgcatc cagttaataa agcactcatg aaattttgta gg
//
LOCUS       DAPGUL010000133        11851 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.136, whole genome shotgun sequence.
ACCESSION   DAPGUL010000133 DAPGUL010000000
VERSION     DAPGUL010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11851
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.136"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            83..2239
                     /locus_tag="RHX21_003952"
     CDS             83..2239
                     /locus_tag="RHX21_003952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001379438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerB N-terminal domain-containing protein"
                     /protein_id="HDV1989072.1"
                     /translation="MHNEDSEDDNLATFTLSGGRNAEYSITATQRQNFSKTTGALARW
                     ILPGEVITVGGVEITGGYFYLGQRMNPVGHNSGGYYDDSSEASLIDDTLKIYPTSYIY
                     EDSSLGYWPSYSSLSPEARGAYLSWLTSDRCDTSCPIGYVFIYLYGLERRALVDSRDS
                     NISDDEFYSLFKEICRLRSVFNENRSFRNYSSQLLEAMSILRPNENLAAALSDDSEFS
                     NSMQFRLILAKTVDAGAPVPADLALTWVTNHTEYSLRTPARRCAKEFAALFKRRYTLK
                     YGEGMVVKPNKARLRLDYTPASPSLRGIRLPVPDLPDPSALKGPVQKLMTLADICTDE
                     LDAYSRYLGRKGTSANDTVAILLLPSEIVNESADKILSAFKRWADDAILSKGGVVSVA
                     DFWSHMNATCPAKINKKEADLMQAFAQKMGYCLAPDPYYHHVKADVDGVLVLFPAGES
                     GRFSPSPEFITAVLTLRLGSVVALIDNSFDQAEQKVLENAINNNVSFSDDEKRSLHAY
                     LTWQLHTPANMTGMKSRIELLGAAEKSAVGKVIVSVACSDGRITPAEIKQLEKIYTSL
                     GLDPSSVSSNIHQHSVTETALVSSVPANQSTAGFTLDANVLARHESATDDVRKLLNSI
                     FTEEEPEQPESAPASLTGEGGLDSAHSQLYRRLLEKEQWSRKEATELCSNWNLMLGGA
                     LEVINDWSYAVVDAPVLEDADDHIWVDLEIAKELEG"
     gene            2243..3559
                     /locus_tag="RHX21_003953"
     CDS             2243..3559
                     /locus_tag="RHX21_003953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000117530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDV1989073.1"
                     /translation="MSVTRIRVKERDAIIQSLKSGVTPRIGIQHIQVGRVNEITALHQ
                     DIERIADGGASFRLIIGEYGSGKTFFLSVVRSIALEKKLVTVSADLSPDRRIHSSGGQ
                     ARNLYSELMKNMSTRNKPDGNALLSVVERFVTEARKEADANGSQVSSVIHKRLAALSD
                     MVGGYDFAKVIDAFWRGHEQDNETLKSNAIRWLRGEYTTKTDARNDLDVRTIISDASF
                     YDSLKLMSLFVRQAGYAGLLVSLDEMVNLFKLNNTQARTANYEQILRILNDCLQGSAE
                     NIGFILGGTPEFLFDPRKGLYSYEALQSRLAENRFAQKAGVIDYSSPTLHLASLTPEE
                     LYILLKNLRHVYAGGDPANYLVPDEALTGFLHHCSKTIGDAYFRTPRNTIKGFLDMLA
                     VLEQNSTMNWQALIEGVAIEEDKPSDMGDAIVEESDDDDGLANFRL"
     gene            3556..5754
                     /locus_tag="RHX21_003954"
     CDS             3556..5754
                     /locus_tag="RHX21_003954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001403205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDV1989074.1"
                     /translation="MSSAYNSLDPRVRKWIYKQGWSSLRPLQESSIPAILARDRDVLI
                     SAGTAAGKTEAFFLPACSAIADLTGGFGIIYISPLKALINDQHRRLESLGEALEMQVT
                     PWHGDVPQSKKKKARTSPSGILLITPESLESLLINSLGWLKQAFSSVAYIVIDEFHAF
                     IGSERGIQLLSLLNRIDHVLGRQLNPVPRVALSATLGELEKVPELLRPDKRLPCETVT
                     DSNSTATLQVQVKGYLERVPEKGEELQSSAEQLVCADIFRLCRGDSHLVFANSRKRTE
                     SIAAILSDMCEANVVPNEFFPHHGSLARELREALEARLQKGNLPTTAVCTMTLELGID
                     IGKVQSVIQVTPPHSVSSLRQRMGRSGRRDSPSVLRMLITEPELTATSSIVDHLRLQL
                     VQAMAMIRLMISKRWFEPADIRQKHYSTLLHQILAITAQWGGVRADQLWSQLCQTGPF
                     RNVDINDFKSLLKHMGTCGLLSQLASGEIVVGAEGEKLTNHYTFYAVFNTPEEFRIVT
                     GNRTLGTVPVDSPLLPEQHIIFGGRRWKVTEIEVEKKVIYVEATKGGQPPLFSGSGMS
                     VHDVVRQEMLAIYRENDYRIAVGNKRVDYADAAARSLFAEGSDNFQRYNLHNDCFIAS
                     GQNCYVIPWMGDKIVNTITSLLIRCGFKASSFAGVIEVEDSGVASVQRVLKKMLLSGL
                     PSEFELAAVVPDKYLDKYDEYLPETLLAKGYGAQAYDIEGTCTWLQKHLQ"
     gene            6236..7252
                     /locus_tag="RHX21_003955"
     CDS             6236..7252
                     /locus_tag="RHX21_003955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000100143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989075.1"
                     /translation="MSSVRTDKFIRYGFAVVAIVAILITTITTPNPTPYQYIVYRIVL
                     ALAAGCIGAVLPGFLEVKFNGWLRASGAVAIFAIVFFISPDLLQQNPESASKPVPPTV
                     IDAYAVNSSNRDRYLELFRTGQLGQRDKLRIGCVEWSESSCVAAGNFLRLLSEAGWEI
                     DSDAVFRMQPSVPVEGVSIVSRGDDLVGLPKVPPHMGRWSRSDISYEILTAAFKLMGV
                     PVYFSSDPTLQPGTTGVYFGPKPKLDAPVMQKDENVRRELLRYVGLGMTIQRACSQQP
                     VELCGGEIFSWETSVSSFLRQQRFNSDAVNRWLALPQVNAASATADMKIKLDLLMSFV
                     LGIE"
     gene            7895..10255
                     /locus_tag="RHX21_003956"
     CDS             7895..10255
                     /locus_tag="RHX21_003956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HDV1989076.1"
                     /translation="MNSMQSKTGSPLVRTEAELESRLTSALNIAFPNIPREDLIEQRH
                     FTVRLGHGTYKIDSAAHWKKYGRADVLIFHRERPLAVIELKREDLTLTHDDYEQAQSY
                     ANQLTPRPPLVVVTNGKDTRVYDSSNGQQWSGGQDASAAVNKMLANSAKLAAADMRWA
                     IEALMGRETNAWVPAVREETARLLIDITDQPGHSEHPFANNLLFPRKITSLVIESAVM
                     GTAFTIIEGDAQSGKSSCLREISLKTESSDLLAVLMLRGSGPGLFQALANLFAAEFEW
                     NLTSNDARNWLRRMSNCTEGPSLMLAIDDVEPGSQMATYLEELAGIRFGNRLVVVLTT
                     YHANALLKNPNGRTPSAIGSRSKVFKTSPMSLDEFKLAQQILSDQRIVFQQGAEYADD
                     YRSPWVLRTIYDDIVRNHQYQKTDLIAYLPPSPGMELIDAAQKSYESQYDLLRYYRVL
                     ARCALADTNSHSVELMFAKANGFVVRYDALSDEARGVVNELKHMGAVRIFRLSGWEDV
                     VVPTVPAAYLLELSDAVCDELVLRAEQDPQDAGAWLGERLDATYLGDMIGAQAIRRMA
                     AKERYFSFGIIQGLLSIEPYKEPIKNGLFTLAMPDNQQVNLKIEDGLAWISKHGDDAK
                     SVLVNLEDQIPKVISKSTSWMILGQLAKLPSAEVGDDDQRIDAYILLSIGRCPFPLIR
                     TNIEGLPYFEHNFGDQGDVLCLEKASIEVATQAMADLFSAPWLYADQWVDTAIATGSI
                     HLLHRLFAALNTVILRRIPVQSDWANEALNQRVSPALKEAIRSLSS"
     gene            10432..11571
                     /locus_tag="RHX21_003957"
                     /pseudo
     CDS             10432..11571
                     /locus_tag="RHX21_003957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612091.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(11568..11723)
                     /locus_tag="RHX21_003958"
     CDS             complement(11568..11723)
                     /locus_tag="RHX21_003958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000160236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989077.1"
                     /translation="MTKGNISERDFDILIKLSGIHSEKAILALKKYYVDGVIRKIDPT
                     HVMWTRP"
BASE COUNT         3080 a         2654 c         2964 g         3153 t
ORIGIN      
        1 gtccgcgggc tcttatactt ccgctcctgt gaaagcacca cctaaagaat ggcttgctaa
       61 taacaaaaaa aatcagtctg taatgcacaa cgaggacagc gaagatgaca atctggctac
      121 gtttacacta agtggcgggc ggaatgccga atacagtata acagccactc aacgccagaa
      181 tttctcaaaa actaccggtg ctttggctcg ctggatttta ccgggggagg tgatcacagt
      241 cggtggggta gagattaccg gcggctactt ctatcttgga cagcgaatga accctgtcgg
      301 gcataactca ggcggttatt atgatgatag tagcgaggca tcgctaattg acgacacgct
      361 caagatatac cccacatctt acatctacga agatagttca ttagggtatt ggcccagtta
      421 ttcctcactt tcacctgaag cacgtggcgc gtacctgagt tggcttacca gcgacagatg
      481 tgacacttct tgcccaattg gttacgtttt tatttatctg tatggtctgg aaagacgggc
      541 gcttgttgac agcagggaca gcaatatatc tgacgatgag ttctattctc ttttcaaaga
      601 gatctgccgt ctcagatctg ttttcaatga aaacagatca ttccggaact actcgtccca
      661 gttacttgaa gcgatgtcca ttcttcgtcc gaacgaaaat cttgcagcag ctctcagcga
      721 tgattcagag ttcagcaata gcatgcagtt caggttaatc ctggcaaaga ctgttgatgc
      781 aggagccccg gttccagcgg atctggctct gacgtgggtg acaaaccata ctgaatactc
      841 attacgaacc cccgcccgcc gctgtgcgaa agaatttgct gcactattta aacggcgtta
      901 cacccttaaa tacggtgaag ggatggtagt gaagccgaat aaagcgcgtc tgcgtttaga
      961 ttacacgcct gcaagtccca gtttgagagg tattcggctt cctgttcctg acttgcctga
     1021 tccaagtgca ttgaaaggcc ctgttcagaa gcttatgact cttgctgata tatgcacaga
     1081 tgaactggat gcttacagtc gttaccttgg tagaaaaggc acttcagcaa atgataccgt
     1141 tgcaattttg ttgctgcctt cagaaatcgt taacgaaagc gcagataaaa tattaagtgc
     1201 attcaaacgc tgggctgatg acgcgatcct cagtaagggg ggagtagttt cagttgctga
     1261 cttctggtca cacatgaatg ctacctgtcc ggcaaagatc aacaaaaaag aggccgactt
     1321 gatgcaggcc tttgcacaga aaatggggta ctgcctggct cctgacccct attaccacca
     1381 cgtaaaagca gatgtcgatg gtgttcttgt tttattccct gctggtgaaa gtggccgctt
     1441 ctctccttct cctgaattta tcacagctgt attgacgctc cgattaggtt cggtagtcgc
     1501 cttgattgac aattctttcg atcaagccga acagaaagtg cttgagaatg ccatcaacaa
     1561 caatgtcagc ttcagcgatg atgaaaagcg ctctctgcac gcatatttaa cgtggcagct
     1621 tcataccccg gcgaatatga cgggaatgaa aagccggatt gaattactcg gtgcagcgga
     1681 aaaatcagct gtgggtaagg ttatcgttag tgtcgcttgc tctgacggca gaattacgcc
     1741 tgccgaaatc aaacagcttg agaagattta tacaagcctg gggttggatc cctcatccgt
     1801 atcaagcaat atccatcagc attccgtaac tgaaactgct ctcgtttcat ctgtaccagc
     1861 taatcagtcg acggcagggt ttacgctgga tgccaatgta cttgcccgcc acgaatctgc
     1921 cactgatgat gttcgtaaat tactgaactc gattttcact gaagaagaac cagaacaacc
     1981 agaaagcgct ccagcctcat taaccgggga aggggggctt gactccgctc atagccaact
     2041 ttatcgcagg ttgctggaga aagaacaatg gtccagaaaa gaggcgacag agttgtgtag
     2101 taactggaac ctgatgctcg gcggtgcgct tgaggtgatt aacgattggt cctatgcggt
     2161 ggttgatgca ccagtgctgg aagatgctga tgatcacatt tgggttgacc tggaaatagc
     2221 caaagaatta gagggttagt gaatgtctgt aacacgtata agagtgaaag agcgcgacgc
     2281 tattattcag tcacttaagt cgggagtaac gccaaggata ggtattcagc atatccaggt
     2341 tggccgcgtg aatgagataa ccgccctcca tcaggatatt gaacggattg ctgatggcgg
     2401 ggcaagcttc agacttatca ttggtgagta tggttccggc aaaacgttct ttttaagtgt
     2461 tgtacggtct attgcgttag agaaaaagct ggtcacggtc agtgcagacc tttctcccga
     2521 cagacgtatt cactcatcgg gaggtcaggc tcgtaatctc tactcagagc ttatgaaaaa
     2581 tatgtccacc agaaacaaac cagatggcaa tgcattactt agcgttgtgg aaaggtttgt
     2641 tactgaggca aggaaggaag ctgatgcgaa cggctcccag gtctcatccg ttattcataa
     2701 acgccttgct gctttgtcag atatggtggg tggatatgac tttgcgaagg tcattgacgc
     2761 attctggcgc gggcatgagc aggataacga aaccttaaaa tccaatgcta ttcgctggtt
     2821 gcggggcgag tacaccacaa aaactgatgc ccgtaatgat cttgacgtcc gaacgattat
     2881 ctcagacgcc tcgttctatg actctttgaa gttgatgagc ctttttgtcc gtcaggcagg
     2941 ctatgccgga cttttagtta gcctcgacga gatggtgaac ctcttcaagt tgaataatac
     3001 gcaagcgaga acggccaact acgaacaaat tttgcggatc ctgaatgact gcctgcaagg
     3061 ctccgccgaa aatattggtt ttatcctcgg ggggacgcca gagtttcttt tcgatccacg
     3121 taaggggctc tacagctatg aagcgctcca gtcgcgtctg gcagaaaatc gattcgcaca
     3181 gaaagctggc gtgattgact actcgtctcc cacgctacat cttgccagcc tcactcctga
     3241 ggaactgtat attttactga aaaatcttcg tcatgtttat gctggtggag atcccgcaaa
     3301 ttatctggtg ccagatgagg ctctgaccgg gtttctgcat cactgcagca aaaccatcgg
     3361 agatgcttac tttcgaactc cccgcaatac cataaaaggt tttctggata tgctggctgt
     3421 gctggaacaa aacagtacga tgaactggca agctctcatt gagggggtgg cgattgaaga
     3481 agacaagccc agcgatatgg gggatgccat tgtggaggaa agtgatgacg atgatggcct
     3541 ggcgaatttc agactatgag cagtgcctac aatagtctcg atccccgtgt ccgtaagtgg
     3601 atttataagc agggctggtc atcattaagg cccttgcagg agagctctat tccggcaatt
     3661 ttagcccgtg atcgtgatgt actaattagt gcaggtacag ctgcgggtaa aacagaggct
     3721 ttctttcttc ctgcctgttc agcgattgca gatctcactg gtggatttgg cattatctat
     3781 atcagtccgt tgaaggcatt gattaacgat cagcaccgtc gtcttgagag cctgggggaa
     3841 gccctggaaa tgcaagtgac gccctggcac ggggatgtac cacaaagcaa aaagaagaaa
     3901 gcacggacaa gcccgtcagg tatcttactt atcacacctg aatcacttga gtctttgctc
     3961 ataaactcat tgggttggct caaacaggcg ttttcttcag tggcatacat tgttattgat
     4021 gagttccacg cttttattgg ctcagagcgt ggtatacaac tgctttcgct gcttaataga
     4081 attgaccatg tgctgggacg ccagttaaat ccagttcccc gtgtcgcgtt gagtgccact
     4141 ctgggagagc tggaaaaagt gccagaatta ttgcgtccgg ataagagatt accttgtgaa
     4201 acggtaacag acagtaatag caccgctaca ctacaagttc aggttaaagg ttatcttgag
     4261 cgggtgcccg aaaaagggga agagctccag agctctgctg aacagctcgt ctgcgcggat
     4321 attttcaggc tctgtcgtgg cgattcccac ctggtctttg ctaacagtcg aaagcgtact
     4381 gaaagcatag cggcaatact gagcgacatg tgtgaagcaa atgtcgttcc taatgaattc
     4441 tttcctcatc atggctccct tgccagggag ttacgtgagg cgcttgaagc ccgactgcag
     4501 aaagggaatt tgcccacaac cgctgtttgt acaatgacgc tggagctggg tattgatatt
     4561 ggtaaggtgc agtctgtcat acaagtgaca cctccgcatt ctgtttccag tctgcgtcaa
     4621 cgcatgggac gttcagggcg gcgcgattcc ccatcggtgc tgagaatgtt aattactgaa
     4681 cctgaactta ccgcaaccag cagcattgtg gatcatttac ggctgcagtt ggttcaggcg
     4741 atggcaatga tcaggttgat gatctctaag cgctggttcg agcctgcaga tatccggcag
     4801 aaacattact ccacactact acaccagatc ctggctatta ctgcgcaatg gggaggtgtt
     4861 cgtgccgatc aactctggtc acaactttgc cagacaggtc cgttccggaa tgtggatata
     4921 aatgacttta aaagtctgct taaacatatg gggacatgtg gcctgctcag tcaactagcc
     4981 agcggtgaaa tagttgtcgg ggctgagggg gagaagctga ctaatcacta cacgttttat
     5041 gccgtattca atacacctga ggagtttcgc attgtaacgg gaaaccgaac tcttggcaca
     5101 gtgcctgtag actccccact tttgccggag cagcacatca tcttcggcgg acggcgctgg
     5161 aaagtgacag agatcgaggt tgaaaaaaag gttatctatg ttgaggcgac taaaggcggt
     5221 cagccaccac tattcagtgg tagcgggatg tctgttcatg atgttgttcg ccaggagatg
     5281 ctcgctatct acagggaaaa tgattaccgt atcgcggtag gcaacaagag agtcgattat
     5341 gctgatgccg cagccagaag cctctttgcg gaaggaagtg acaacttcca acgctacaat
     5401 ctacacaatg actgttttat tgccagtggt cagaactgct acgtgatccc gtggatgggg
     5461 gataaaattg tcaatacaat tacgtccctg cttatacgtt gtggctttaa agccagttca
     5521 tttgcaggtg tgatagaggt agaggactca ggcgttgcct ctgtccagcg tgtacttaag
     5581 aaaatgctat tgtcggggtt accttcagag tttgagcttg ctgcagttgt tcctgacaag
     5641 tatctggata aatatgacga gtatttacca gagactttgc ttgctaaagg gtatggggca
     5701 caggcgtatg atatagaagg aacgtgcacc tggctgcaga aacaccttca gtagactgga
     5761 tatgtagtca gggtataaat aacttattta taccctgatt tttttacttc ccggtggact
     5821 tacttggctt tagtcccgga gtgttgccag gagtatcttt attatctcgt cggcgttgat
     5881 ctggttttcc tgtcgattta gcaattggtt ttggaccagg tttaagaccc atgatagtta
     5941 tccttttgag atgtaagagg gaagccctca acattggtat attggatact gagaaatttt
     6001 tcaatgggag tgataaacgg ccgaatgatt aactcgatat tgtgatcaac gtctgttttt
     6061 tgcacactgt agactgactc ttggagcaga aggttgctct gagcgaggaa tggacagtta
     6121 cactcatcac caacgccaat agcctcatta cgcgtataaa gctgtattaa tcattgggga
     6181 acagtttaat gcgggatttt cgacttatgg acttgattca ggtgtcaaaa ttaaaatgag
     6241 cagtgtaagg acagacaagt tcattaggta tggttttgcg gttgtggcga tagttgccat
     6301 actcattact actatcacaa cccccaatcc cacaccttat caatatatag tttaccgaat
     6361 agttctggct ctggctgccg gatgtattgg tgcagttctg cctggtttcc ttgaagtaaa
     6421 atttaatggg tggttaagag catctggcgc agtggcgatc ttcgctatag tgtttttcat
     6481 aagcccagat ttgcttcaac aaaatcctga atctgcaagt aaacctgtac cgcctactgt
     6541 gattgatgca tatgccgtta atagttccaa tcgcgacaga tacctcgaat tatttcgaac
     6601 aggacagctc ggtcagcggg acaagctgcg catcggttgt gttgagtgga gtgaatcatc
     6661 gtgcgtggct gctggtaatt ttttgcgatt gttaagcgaa gctggctggg aaatcgattc
     6721 tgacgctgta ttcagaatgc aaccatccgt gccagttgag ggggtatcga ttgtaagccg
     6781 tggcgatgat ctggtcggtt tgccaaaagt accaccccac atgggccgtt ggagtcgatc
     6841 agacattagt tatgaaattt tgacagcggc atttaaattg atgggagttc cggtttattt
     6901 ttccagtgac ccgacattac aaccaggtac taccggagtg tactttggac cgaaaccgaa
     6961 actggatgca ccagtcatgc aaaaagatga gaatgtgcga cgtgagcttc tccgctacgt
     7021 cggtttggga atgactattc agcgagcctg ctctcagcag cccgtcgaac tttgtggggg
     7081 tgaaatcttt tcctgggaaa cgtcggtatc ttcgttccta aggcagcaga gattcaactc
     7141 cgatgccgta aacagatggc ttgccttgcc gcaggttaat gcggcttcgg caactgcaga
     7201 catgaaaata aagctagatt tgttaatgtc atttgttctg ggcatcgagt aactatacct
     7261 cttgcgagga tgattgagcg tctaatggac cagcttagcc gttagcgcta tttgtttacg
     7321 taagcctgtg gaatccaact agtgcttcta cgatgcgttg tttggtgaaa aaaagtgttg
     7381 aagcactggt tttagacaac taaagccacg atttgctcat gcgtcgaaaa tgtagtcgtc
     7441 tactgtgtag cacggaggcg atattcgtac gcttacactt gccgataggc cactggggag
     7501 tgttcttggc actaagctgc caggcccgaa ggtctgctat gagcgagggg ctgacattcc
     7561 tattggcatt cggtgtgagt tatcgggggc ggtcatgcgg catacttccg atacaggcgt
     7621 ttccagctct gcctgtttca gggttatatt aatctgcttt agaattaatc gtggctttag
     7681 catctgcaca tcgtgctgga gaaacctgag tgaactaaat catattccct ttcttcagct
     7741 aatcaattga tagttatgcg gaaaaagtta ctttgcttgt caataatcca tttcacatcc
     7801 gttaatccaa tgctatgcgt cttcgcatta atctggaaag gtagtaagtg aaataaaaac
     7861 ttagccaatg actaatatct gaggatactt tgtcatgaac agtatgcaat caaaaacggg
     7921 ctctccactc gttcgaactg aagccgagct agaaagccgg cttacttcag cactaaacat
     7981 agcatttcct aacattcctc gcgaagatct tatcgaacag cgccatttta ccgttcggct
     8041 aggccatgga acttacaaaa tagatagcgc cgcacactgg aaaaaatacg ggcgagcgga
     8101 tgttttgatc tttcatcggg agagaccact tgcggttatt gaactgaaac gtgaagacct
     8161 gacactgacc catgatgatt atgaacaggc tcaaagctac gctaaccagt taacaccacg
     8221 tccgcctctc gttgtagtta cgaacggtaa agatacgcgc gtttatgact caagtaatgg
     8281 acaacagtgg tcgggtggac aggatgcctc ggcagcggta aacaagatgc tcgccaattc
     8341 tgcaaagttg gcggcggctg acatgcgctg ggctattgaa gccttgatgg ggcgagaaac
     8401 taatgcttgg gtgccagctg tgcgagaaga aacagcccgg ctgctgattg atataactga
     8461 tcagcctggg cattcagaac atccatttgc caacaaccta ctttttcctc gcaaaatcac
     8521 gtctcttgta attgaatctg ctgtgatggg tacagctttc actatcattg agggtgatgc
     8581 acaaagcgga aaaagcagtt gcctccgtga aatttcgcta aaaacggaaa gtagcgatct
     8641 tttggctgtc ctgatgttac gaggttccgg accaggacta tttcaggctc tggccaatct
     8701 ttttgcagct gaatttgaat ggaatttaac ctcaaatgat gcacgtaact ggttaagacg
     8761 aatgtctaac tgcactgaag gtccatcgct tatgcttgct atcgacgacg ttgaaccagg
     8821 ctcccaaatg gctacttatc ttgaggaact tgcgggtata cgttttggca acaggctggt
     8881 ggttgttctg acgacctatc atgccaacgc gttactgaaa aatccaaacg gacgaactcc
     8941 gtctgcaatt ggtagccggt cgaaggtatt taaaacatcg cctatgtccc tagatgaatt
     9001 taagctggcg caacagattc tctcggatca gcggatagtt tttcaacagg gagcagaata
     9061 cgccgatgac taccgctcgc cttgggttct tcgcactatt tatgatgaca ttgtgcgcaa
     9121 tcatcaatac cagaaaacgg atcttatcgc ctatcttcct ccatcacccg gtatggaact
     9181 tatagatgct gcgcaaaaga gctatgagag tcagtatgat cttcttcgtt attatcgggt
     9241 tcttgcacgc tgcgcactag ctgacacaaa ctcccactca gtagaattaa tgtttgctaa
     9301 agcgaatgga tttgtcgtgc ggtatgacgc actttctgac gaagctcgtg gtgtagtgaa
     9361 tgagttaaaa catatggggg cagttcgtat ttttcgcctt tcaggatggg aagatgttgt
     9421 ggtgccgaca gttcccgcag cttaccttct ggaactgtcg gatgctgttt gtgatgaact
     9481 ggttttacgg gcagaacaag accctcaaga cgccggggct tggcttggcg aacggctaga
     9541 cgccacttat cttggagata tgatcggtgc tcaagccata cgccgtatgg cagctaaaga
     9601 gagatatttc agctttggaa ttattcaggg ccttctcagc attgagccat ataaagaacc
     9661 tataaaaaac ggattgttta ctttagccat gccagacaac caacaagtca atctaaagat
     9721 tgaggatgga ttagcgtgga tttctaaaca cggggatgat gcaaagagtg ttctggtgaa
     9781 tttagaggat caaatcccaa aggtcatttc taaatcaacc agttggatga tactcgggca
     9841 actagcgaaa ctgccgtcag cagaggtggg tgacgatgat cagcgtatag acgcctatat
     9901 tttactgagc attgggcgct gcccatttcc tctaattcgc acgaatatag aaggattgcc
     9961 ttactttgag cataattttg gcgatcaggg tgatgttctt tgcctagaaa aagcgtctat
    10021 tgaagttgct actcaggcga tggctgattt attttcagcc ccatggctct atgcggacca
    10081 gtgggtggat acagctatcg cgaccggttc tatacattta ctgcatcgtt tgtttgctgc
    10141 tttaaacaca gtgatattgc gtagaatacc cgtgcaatcc gactgggcta atgaagcact
    10201 taatcaacgt gtctcaccag cccttaagga agccatacga tcattatctt cgtgactaag
    10261 caatgggatt ttaatacata acgagcatct gtccacgcaa gttaacaatt gccttggctc
    10321 gatattttgg tttctagtgc atatatgctg atcttctctt cgttgatctg atcttaccca
    10381 ccaatagtgg acacaggact aagtgagtaa actctcaacc agaggtgact catgacaaaa
    10441 ccagtatcaa tcagcaagaa gccccgtgaa caacattcgc ctgaatttcg taacgaagcc
    10501 ctgaaactcg ctgaacgcat cggtgtggcc gccgcagccc gtgaactcag cctttatgaa
    10561 tctcagcttt atgcctggcg cagtaaacag cagcaacaaa tgagttcgtc agagcgcgaa
    10621 agcgaactgg ccgctgaaaa tgtccgcctt aaacgacaac tggcggagca ggctgaggaa
    10681 ctggccatcc tccaaaaggc cgcgacatac ttcgcgaatc gcctgaaatg aagtatgtct
    10741 tcatcgaaaa tcatcgggca gagttctgca tcaaagcgat gtgtcgtgta cttcgggttg
    10801 cccgcagcgg ctggtatgtc tggctcaggc gtcgtcacca gatgagcctt cgccaacagt
    10861 ttcggctcac ctgcgatgcc gctgtccata aggcattctt tgaggcaaag cagcgatacg
    10921 gtgctccccg ccttgctgac gaactgccgg agttcaatat taaaaccatt gccgccagcc
    10981 tgcgtcgtca ggggctgcgg gcgaaagttc agcccggtca gctaccgtgc acatggcctg
    11041 cccgtattgg agaatctgct ggagcaggac ttcagcgcca gaggcccgaa ccagaagtgg
    11101 gcgggtgaca tcacgtactt gcgtaccgat gagggctggt tgtatctcgc agtagtcatc
    11161 gacctgtggt cacgcgccgt cattggctgg tcgatgtcac cgcgaatgac agcacaactg
    11221 gcctgtgatg cactacaaat ggcgttgtgg cggagaagac gcccggaaag cgtcattgtt
    11281 catacggacc gtggtggtca atactgttca ggggattatc aggcgctgct gaagcgacac
    11341 aacctgcgtg gcagtatgag tgcgaaaggc tactgttatg acaatgcctg tgtggaaagc
    11401 ttctttcatt cgctgaaagt ggaatgtatc cacggggaac gctttagcag tcgggaaata
    11461 atgcgggcaa cggtgtttaa ttatatcgag tgtgattaca atcgctggcg tcgtcacagt
    11521 gcctgtggcg gtctcagccc ggaacaattt gaaaaccata atctcgctta gggccgtgtc
    11581 cacattacgt gggtaggatc aattttcctg atgaccccat cgacatagta ttttttcaaa
    11641 gcaagaattg ccttctcgct atgtattcct gatagcttga tcaggatatc aaagtctctt
    11701 tcagatatat tcccctttgt catgtgtcac tccatgaatc aaatttcata gtaatcaatc
    11761 tttctttgat cgacttatag ataataagat cagaaatgat aaaaaagtaa cgcatatttc
    11821 ttctcgtcat gtctacttat aaaattcaaa t
//
LOCUS       DAPGUL010000134        11850 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.137, whole genome shotgun sequence.
ACCESSION   DAPGUL010000134 DAPGUL010000000
VERSION     DAPGUL010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11850
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.137"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            26..628
                     /locus_tag="RHX21_003959"
     CDS             26..628
                     /locus_tag="RHX21_003959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416376.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebB family permuted papain-like enzyme"
                     /protein_id="HDV1989078.1"
                     /translation="MNINYPAEYEIGDIVFTCIGAALFGQISAASNCWSNHVGIIIGH
                     NGEDFLVAESRVPLSTITTLSRFIKRSSNQRYAIKRLDAGLTEQQKQRIVEQVPSRLR
                     KLYHTGFKYESSRQFCSKFVFDIYKEALCIPVGEIETFGQLLNSNPNAKLTFWKFWFL
                     GSIPWERKTVTPASLWHHPGLVLIHAEGVETPQPELTEAV"
     gene            complement(630..1151)
                     /gene="ruvC"
                     /locus_tag="RHX21_003960"
     CDS             complement(630..1151)
                     /gene="ruvC"
                     /locus_tag="RHX21_003960"
                     /EC_number="3.1.21.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005068993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HDV1989079.1"
                     /translation="MAIILGIDPGSRVTGYGVIRQVGRQLSYLGSGCIRTKVDDLPSR
                     LKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEY
                     AARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQM
                     SESRLNLARGRLR"
     gene            complement(1186..1926)
                     /locus_tag="RHX21_003961"
     CDS             complement(1186..1926)
                     /locus_tag="RHX21_003961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDV1989080.1"
                     /translation="MAGHSKWANTRHRKAAQDAKRGKIFTKIIRELVTAAKLGGGDPD
                     ANPRLRAAIDKALSNNMTRDTLNRAIARGVGGDDDANMETIIYEGYGPGGTAIMIECL
                     SDNRNRTVAEVRHAFSKCGGNLGTDGSVAYLFSKKGVISFEKGDEDTIMEAALEAGAE
                     DVVTYDDGAIDVYTAWEEMGKVRDALEAAGLKADSAEVSMIPSTKADMDAETAPKLMR
                     LIDMLEDCDDVQEVYHNGEISDEVAATL"
     gene            complement(1955..2407)
                     /gene="nudB"
                     /locus_tag="RHX21_003962"
     CDS             complement(1955..2407)
                     /gene="nudB"
                     /locus_tag="RHX21_003962"
                     /EC_number="3.6.1.67"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin triphosphate diphosphatase"
                     /protein_id="HDV1989081.1"
                     /translation="MTDMAYKRPVSILVVIYAQDTKRVLMLQRRDDPDFWQSVTGSVE
                     EGETAPQAAVREVKEEVTIDVVAEQLTLIDCQRTVEFEIFSHLRHRYAPGVTRNTESW
                     FCLALPHERQIVFTEHLAYKWLDAPAAAALTKSWSNRQAIEQFVINAA"
     gene            complement(2400..4172)
                     /gene="aspS"
                     /locus_tag="RHX21_003963"
     CDS             complement(2400..4172)
                     /gene="aspS"
                     /locus_tag="RHX21_003963"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HDV1989082.1"
                     /translation="MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGI
                     VQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTII
                     NRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDI
                     ETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRD
                     EDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAE
                     RRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLTRKQI
                     DEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEAILDRTAAQDGDMI
                     FFGADNKKIVADAMGALRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHP
                     FTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEE
                     EQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTE
                     APSFANPTALAELSIQVVKKAENN"
     gene            4482..5048
                     /locus_tag="RHX21_003964"
     CDS             4482..5048
                     /locus_tag="RHX21_003964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416381.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDV1989083.1"
                     /translation="MLELNAKTTALVVIDLQEGILPFAGGPHTADEVVNRAGKLAAKF
                     RASGQPVFLVRVGWSADHAEALKQPVDAPSPAKVLPENWWQHPAALGATDSDIEIIKR
                     QWGAFYGTDLELQLRRRGIDTIVLCGISTNIGVESTARNAWELGFNLVIAEDACSAAS
                     AEQHNNSINHIYPRIARVRSVEEILHAL"
     gene            5045..5863
                     /locus_tag="RHX21_003965"
     CDS             5045..5863
                     /locus_tag="RHX21_003965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HDV1989084.1"
                     /translation="MIYIGLPQWSHPKWVRLGITSLEEYARHFNCVEGNTTLYALPKP
                     EVVLRWREQTTDDFRFCFKFPATISHQAALRHCDDLVTEFLTRMSPLAPRIGQYWLQL
                     PATFGPRELPALWHFLDSLPGEFNYGVEVRHPQFFAKGEEEQTLNRGLHQRGVNRVIL
                     DSRPVHAARPHSEAIRDAQRKKPKVPVHAVLTATNPLIRFIGSDDMTQNRELFQVWLQ
                     KLVQWHQTTTPYLFLHTPDIAQAPELVHTLWEDLRKTLPEIGAVPAIPQQSSLF"
     gene            5916..6311
                     /locus_tag="RHX21_003966"
     CDS             5916..6311
                     /locus_tag="RHX21_003966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310606.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MAPEG family protein"
                     /protein_id="HDV1989085.1"
                     /translation="MVSALYAVLSALLLMKFSFDVVRLRLQYRVAYGDGGFSELQSAI
                     RIHGNAVEYIPIAIVLMLFMEMNGAETWMVHICGIVLLAGRLMHYYGFHHRLFRWRRS
                     GMSATWCALLLMVLANLWYMPWELVFSLR"
     gene            6352..7095
                     /gene="cmoA"
                     /locus_tag="RHX21_003967"
     CDS             6352..7095
                     /gene="cmoA"
                     /locus_tag="RHX21_003967"
                     /EC_number="2.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxy-S-adenosyl-L-methionine synthase CmoA"
                     /protein_id="HDV1989086.1"
                     /translation="MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIIS
                     MIGMLAERFVQPGTQVYDLGCSLGAATLSVRRNIHHDNCKIIAIDNSPAMIERCRRHI
                     DAYKAPTPVDVIEGDIRDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGAL
                     VLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARL
                     HKAGFEHSELWFQCFNFGSLVALKAEDAA"
     gene            7092..8063
                     /gene="cmoB"
                     /locus_tag="RHX21_003968"
     CDS             7092..8063
                     /gene="cmoB"
                     /locus_tag="RHX21_003968"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic
                     acid(34) synthase CmoB"
                     /protein_id="HDV1989087.1"
                     /translation="MIDFGNFYSLIAKNHLSHWLETLPAQIANWQREQQHGLFKQWSN
                     AVEFLPEIKPYRLDLLHSVTAESEEPLSAGQIKRIETLMRNLMPWRKGPFSLYGVNID
                     TEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGIDPTQLFLCQ
                     FEAVRKLLGNDQRAHLLPLGIEQLPALKAFDTVFSMGVLYHRRSPLEHLWQLKDQLVN
                     KGELVLETLVIDGDENTVLVPGDRYAQMRNVYFIPSALALKNWLKKCGFVDIRIADVS
                     VTTTEEQRRTEWMVTESLADFLDPHDPGKTVEGYPAPKRAVLIARKP"
     gene            complement(8228..10657)
                     /gene="torZ"
                     /locus_tag="RHX21_003969"
     CDS             complement(8228..10657)
                     /gene="torZ"
                     /locus_tag="RHX21_003969"
                     /EC_number="1.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310609.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethylamine N-oxide reductase TorZ"
                     /protein_id="HDV1989088.1"
                     /translation="MTLTRREFIKHSGIAAGALVVTSAAPLPAWAEEKGGKILTAGRW
                     GAMNVEVKDGKIVSSTGALAKTIPNSLQSTAADQVHTTARIQHPMVRKSYLDNPLQPA
                     KGRGEDTYVQVSWEQALKLIHEQHDRIRKANGPSAIFAGSYGWRSSGVLHKAQTLLQR
                     YMNLAGGYSGHSGDYSTGAAQVIMPHVVGSVEVYEQQTSWPLILENSQVVVLWGMNPL
                     NTLKIAWSSTDEQGLEYFHQLKKSGKPVIAIDPIRSETIEFFGDNATWIAPNMGTDVA
                     LMLGIAHTLMTQGKHDKVFLEKYTTGYPQFEEYLTGKSDNTPKSAAWAAEITGVPEAQ
                     IVKLAELMAANRTMLMAGWGIQRQQYGEQKHWMLVTLAAMLGQIGTPGGGFGFSYHYS
                     NGGNPTRVGGVLPEMSAAIAGQASEAADDGGMTAIPVARIVDALENPGGKYQHNGKEQ
                     TYPNIKMIWWAGGGNFTHHQDTNRLIKAWQKPEMIVVSECYWTAAAKHADIVLPITTS
                     FERNDLTMTGDYSNQHIVPMKQAVAPQFEARNDFDVFADLAELLKPGGKEIYTEGKDE
                     MAWLKFFYDAAQKGARAQRVTMPMFNAFWQQNKLIEMRRSEKNEQYVRYGDFRADPVK
                     NALGTPSGKIEIYSKTLEKFGYKDCPAHPTWLAPDEWKGTADEKQLQLLTAHPAHRLH
                     SQLNYAELRKKYAVADREPITIHTEDAARFGIANGDLVRVWNKRGQILTGAVVTDGIK
                     KGVVCVHEGAWPDLENGLCKNGSANVLTADIPSSQLANACAGNSALVYIEKYTGNAPK
                     LTAFDQPAVQA"
     gene            complement(10682..11782)
                     /locus_tag="RHX21_003970"
     CDS             complement(10682..11782)
                     /locus_tag="RHX21_003970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707761.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NapC/NirT family cytochrome c"
                     /protein_id="HDV1989089.1"
                     /translation="MRGKKRIGLLFLLIAVVVGGGGLLLAQKALHKTSDTAFCLSCHS
                     MSKPFEEYQGTVHFSNQKGIRAECADCHIPKSGMDYLFAKLKASKDIYHEFVSGKIDS
                     DDKFETHRQEMAETVWKELKATDSATCRSCHSFDAMDIASQSESAQKMHNKAQKGGET
                     CIDCHKGIAHFPPEIKMDDNAAHELESQTATSVTNGAHIYPFKTSRIGELATVNPGTD
                     LTVVDASGKQPIVLLQGYQMQGSENTLYLAAGQRLALATLSEEGIKALTVNGEWQADE
                     YGNQWRQASLQGALTDPALADRKPLWQYAEKLDDTYCAGCHAPIAADHYTVNAWPSIA
                     KGMGARTSMSENELDILTRYFQYNAKDITEKQ"
BASE COUNT         2713 a         3158 c         2891 g         3088 t
ORIGIN      
        1 gtatcgattt caatggaatg acaacgtgaa tattaattac cctgctgaat atgaaattgg
       61 agatatcgtc tttacatgta taggtgctgc cttatttggt caaatatcag ctgcatcaaa
      121 ttgctggagt aatcacgtcg ggatcattat cggtcataac ggtgaagact tcctggttgc
      181 agaaagccgg gttccccttt caaccatcac cacgctatct cgttttatta aacgttcgtc
      241 taatcaacgc tatgctataa agcgattaga cgctgggctg acagaacaac aaaaacaacg
      301 aattgttgaa caggttcctt cccggctacg caaactttac cacacgggtt ttaaatacga
      361 atcttcccgc cagttctgtt caaaatttgt ctttgatatt tataaagagg cgctatgtat
      421 tccggtgggt gaaatagaga cgtttggaca actgttaaat agcaatccga atgcaaaact
      481 cactttctgg aaattctggt tcttaggttc tattccgtgg gagcgtaaaa ccgtcacgcc
      541 agccagtttg tggcatcatc cgggtttggt gttgattcac gcggagggag ttgaaacgcc
      601 tcagcctgaa ctgaccgagg cggtataact taacgcagtc gccctctcgc caggttcagc
      661 cgcgattcgc tcatctgcat cgcattctga ctgacgtgac aatgggtaat cgcgatagct
      721 aacgcatcgg cggcatccgc ctgtggatta gcgggcagtt tcagcaaggt gcggaccata
      781 tgctgcacct ggcttttttc ggcactacca atacctacca ccgtttgctt tacctgacgt
      841 gccgcgtatt caaataccgg caattcctga ttcaccgccg caacaatcgc cacgccgcgc
      901 gcctggccca gtttcagggc tgagtcagcg ttcttcgcca taaagacttg ttcaatggcg
      961 aaataatcag gctggaactg ggtgatgatt tccgtcacgc ccgcatagat gagcttcaga
     1021 cgagacggta aatcatccac tttggtgcgt atgcatccgc tacccaggta ggacagttgc
     1081 ctgcctacct ggcgaattac gccatagccg gtcacgcgcg aacccggatc aatgccgaga
     1141 ataatagcca tcacgcgtct ccgttttgct gtttagcagg cctcatcaga gagtcgctgc
     1201 gacctcatca gagatttcac cgttatggta aacttcctgc acgtcgtcgc aatcttccag
     1261 catatcgatc agacgcatca gtttcggtgc ggtttctgca tccatatcag ctttggtgga
     1321 cgggatcatg gaaacttccg cgctgtctgc tttcagacct gccgcttcca gagcgtcgcg
     1381 cactttaccc atttcttccc atgcagtgta gacatcaatc gcgccgtcat cataggtcac
     1441 aacgtcttca gcacctgctt ccagagctgc ttccatgatg gtgtcttcat cgcctttctc
     1501 gaaggagatc acgccttttt tgctgaacag ataggctacg gaaccatctg taccgaggtt
     1561 accgccacat ttgctgaatg catgacgcac ttcagcaacg gtacggttgc ggttgtcaga
     1621 cagacattca atcatgattg ccgtgccgcc aggaccgtaa ccttcgtaga tgatggtttc
     1681 catgtttgca tcatcatcac cgcccacacc acgtgcaatt gcgcggttca gtgtgtcgcg
     1741 ggtcatgttg ttagacagtg ctttatcaat tgctgcacgc agacgcgggt tagcgtccgg
     1801 atcgccaccg cccagcttag ccgcggttac cagctcacga atgattttag tgaagatttt
     1861 accgcgcttt gcatcctgcg cagctttacg atgtctggtg ttggcccatt tactatgacc
     1921 tgccataaaa atatctccag atagccctgc ctgttcaggc agcgttaatt acaaactgtt
     1981 caatcgcctg ccggttgctc caggacttag tgagcgccgc cgcagcaggc gcatcaagcc
     2041 acttgtaagc cagatgttca gtgaaaacga tctgccgctc gtgtgggagc gcaagacaga
     2101 accatgattc cgtattacgc gtcacgcccg gcgcatagcg atgacgtaaa tgtgaaaaaa
     2161 tttcaaactc taccgtgcgc tgacagtcaa ttaaggtcag ttgttcagcg acaacatcaa
     2221 tggtgacctc ttcctttact tcgcgcacgg cagcttgcgg cgcggtttcc ccctcttcca
     2281 cgctgccggt taccgactgc cagaaatcgg gatcgtcacg ccgctgcaac atcagcaccc
     2341 gtttcgtatc ttgtgcgtag atgaccacta agatcgaaac gggacgctta taagccatat
     2401 cagttattct cagccttctt cacaacctga atgctcagct cagccagtgc agtcgggtta
     2461 gcaaagctcg gtgcttcagt catcagacac gctgccgccg tggttttcgg gaaggcaata
     2521 acgtcacgga tattgtcggt gccggtcagc agcatggtca gacggtcaag accgaatgcc
     2581 agacctgcgt gcggcggagt accgtatttc agagcgtcga gcaggaagcc gaatttctcg
     2641 cgctgttcct cttcgttgat acccagaata ccaaacaccg tctgctgcat atcaccatta
     2701 tggatacgta ctgaaccacc gcccacttcg taaccattga tgaccatatc gtaagcgttc
     2761 gccaccgcat tttccggtgc agctttcagt tctgcagcag tcatgtcttt cggtgaggtg
     2821 aacggatggt gcattgccgt caggccgcct tcaccgtcgt cttcaaacat cgggaagtcg
     2881 ataacccaca gcggtgccca tttgctttcg tcggtcagac caaggtcttt acccactttc
     2941 aggcgcagtg cgcccatcgc gtcggcaaca attttcttgt tgtcggcacc gaagaaaatc
     3001 atatcgccat cttgcgcggc agtacgatcc aggatggctt cgatgatttc tgcattaagg
     3061 aacttcgcta ccgggctgtt gataccttcc agacctttcg cgcgttcgtt aactttgatg
     3121 taagccagac ctttcgcgcc gtagatttta acgaagttac cgtattcgtc gatctgctta
     3181 cgggtcagcg atgcgccgcc cggaacgcgc agagcggcaa cgcgaccttt cggatcgttc
     3241 gccggacctg caaatactgc aaactcaaca gatttcagca gatcagcaac gtcggtcagt
     3301 tccatcgggt tacgcagatc cggtttatca gaaccataac ggcgttctgc ttccgcaaag
     3361 gtcattaccg ggaaatcgcc cagatccacg cccttcactt ccagccacaa atgacgcacc
     3421 agcgcttcca tcacttcacg cacttgcggc gcggtcatga aagaagtttc cacatcgatc
     3481 tgagtaaatt caggctgacg atcagcgcgc aggtcttcgt cacggaagca tttaacgatc
     3541 tgatagtaac ggtcaaaacc ggacatcatc agcagctgtt tgaacaactg tggggattgc
     3601 ggcagtgcgt agaatttacc tttgtgcaca cgagaaggca ccaggtagtc acgcgcgcct
     3661 tccggcgtgg ctttggtcag catcggagtt tcgatgtcga ggaagccgtg gtcatccata
     3721 aaacggcgca ccaggctggt gattttagcg cgggttttca ggcgctgcgc catttccggg
     3781 cgacgcaggt cgaggtagcg gtatttcaga cgcgcttctt cggtgttgac gtggttagag
     3841 tcaagcggca gaacatctgc gcggttgatg atagtcagcg aggacgccag cacttcaatt
     3901 tcgccggtcg ccatatcgcg gttaatattt ttttcgtcac gcgcacgtac ggtgcccgta
     3961 acctgaatgc agaactcatt acgcagttca gaggccagct ttaacgcgtc cgcacgatcc
     4021 ggatcgaaaa atacctgcac gataccttcg cggtcgcgca tatcgatgaa gatcaggcta
     4081 ccaagatcac gacgacggtt gacccaacca cacagagtca cctgctgccc cacgtgggac
     4141 aaacggagct gtccacaata ttctgtacgc atgagatatc ccttaactta gctgccggcg
     4201 gatgccccct gctgcgcagg tgaccaagtc gcagcgttag ctgtatgtca caactgaatg
     4261 aaaaaaggcg gctattatac tggaaattct gccgcaccgt aagagcctgg cccgcgctgg
     4321 aacgcctcgt taccacttta tatcgggcct gaaatcagac tctacgccag tttgctataa
     4381 aggtgttgcc cgaactcata aaaattaaca aaatttgtcg ttccgccatc ggctaatcgc
     4441 attaaggtgt gaggcacgat tttgtttttt caggagtcag catgcttgaa cttaatgcta
     4501 aaaccactgc gttggtggtg atcgatttac aagaaggcat cttacctttt gccggtggtc
     4561 cacatactgc cgatgaggta gttaatcgcg ccgggaagct ggcggcgaaa tttcgcgcca
     4621 gcggtcagcc cgtgtttctg gtgcgcgttg gctggtctgc cgatcacgcc gaagcattaa
     4681 aacagccggt tgatgccccc tcccccgcta aagtgttgcc cgaaaactgg tggcaacatc
     4741 cagctgcatt aggtgcaact gacagtgata tcgaaatcat caaacgtcag tggggtgcgt
     4801 tttacggtac ggatctggag ttgcaactgc gccgccgagg tatcgataca atagtgttat
     4861 gtgggatctc gaccaatatc ggtgttgaat ccaccgcccg caatgcctgg gaacttggct
     4921 ttaatctggt gattgccgaa gacgcctgta gtgccgccag cgccgagcag cacaataaca
     4981 gcatcaacca tatctaccca cgcatcgccc gtgtgcgtag cgtggaagag atccttcacg
     5041 cgttatgatt tacatcggtc taccgcaatg gtcgcatcct aaatgggtgc ggttgggaat
     5101 caccagcctt gaagagtatg cccgccactt taactgcgtg gagggcaaca ccacgcttta
     5161 cgccctgccg aaacccgagg ttgtcctgcg ctggcgtgaa cagaccacag atgacttccg
     5221 cttctgtttt aagtttccgg cgaccatttc gcatcaggca gcattacgac attgcgatga
     5281 tttagtgact gaatttttga cccgcatgtc accgttggct ccgcgcattg ggcaatactg
     5341 gctgcaactg cctgccacat tcggcccacg ggagctgcct gcgctttggc attttctcga
     5401 ttctctccct ggcgaattta attatggtgt ggaagtccgc catccacagt ttttcgccaa
     5461 aggggaagag gaacaaacgc ttaatcgcgg tttacatcag cgcggcgtta atcgggtgat
     5521 tttagacagc cgcccggttc atgcagcacg tccacacagt gaagctattc gcgacgctca
     5581 acgaaaaaaa cctaaagttc cggtacatgc tgtactgacg gcgacaaatc cgctgatccg
     5641 ttttatcggt agtgatgata tgacgcaaaa ccgggaatta tttcaggtct ggttacaaaa
     5701 attagtgcag tggcatcaga ccactacgcc ttatcttttt ttacatacgc cagacattgc
     5761 ccaggccccg gaactggtac ataccctgtg ggaagactta cgtaaaacgc ttccagagat
     5821 cggagcagtt ccggctattc cacagcaatc ttctcttttc tgaatttgcc acctatcata
     5881 gacaggtgcc atcggccatt ttaaagggag tttgtatggt aagcgcgctg tatgccgttt
     5941 taagtgcgtt gttattaatg aagttctctt ttgatgtcgt tcgcttgcgt ttgcagtacc
     6001 gcgttgccta tggtgacggt ggttttagcg aactgcaaag cgctattcgc attcatggta
     6061 acgcggtgga atatattccc atcgcgattg tgctgatgct gtttatggaa atgaatggcg
     6121 cagaaacctg gatggtgcat atttgcggca tcgttttgct tgctggtcgt ctgatgcatt
     6181 attacggttt tcatcaccgt ctgttccgct ggcgacgttc cggcatgagc gccacctggt
     6241 gtgcgctgtt gctgatggtg ctggcgaatc tttggtatat gccctgggag ttggttttct
     6301 ccctgcgtta gcgcacaata cgccactttc tttttcccgg atttttacgt tatgtctcac
     6361 cgcgacacgc tattttctgc ccctatcgcc agactgggcg actggacctt tgatgaacgg
     6421 gtagctgaag tcttcccgga tatgatccag cgttccgttc ccggctattc caatattatt
     6481 tccatgattg gtatgttagc cgagcgcttc gttcaacctg gtacgcaggt ttacgatctg
     6541 ggttgttctc tgggcgcggc gacgctctcg gtgcgtcgca acattcatca tgataattgc
     6601 aaaattattg ccatcgacaa ctccccggcg atgattgaac gctgccgtcg tcatattgac
     6661 gcctataaag cccctacgcc agtagacgtc attgaaggtg atattcgcga tatcgccatt
     6721 gaaaacgcat cgatggtggt gctgaatttt accctgcaat tcctggaacc ttccgagcgc
     6781 caggcattac tggataaaat ttatcaagga ctgaacccgg gcggcgcgct ggtgctttcg
     6841 gaaaaattca gtttcgaaga tgccaaagtt ggtgaactgt tgttcaacat gcaccacgac
     6901 tttaaacgtg ccaacggtta cagcgaactg gagatcagcc agaagcgcag catgctggaa
     6961 aacgtgatgc tgaccgattc cgtggaaacc cataaagcac gcctgcataa agccggtttt
     7021 gagcatagcg agctgtggtt ccagtgcttt aactttggtt cactggtggc attaaaagca
     7081 gaggacgctg catgatcgac tttggtaact tttattctct gattgccaaa aatcatcttt
     7141 cacactggct cgaaacgctg cccgcgcaga ttgctaactg gcagcgcgag cagcagcacg
     7201 ggttgtttaa gcagtggtca aatgcggtgg agtttctacc tgaaattaaa ccgtatcgtc
     7261 ttgatttatt gcatagcgtt acggcagaaa gcgaagagcc actgagcgca gggcaaatta
     7321 aacgcattga aacgctgatg cgcaacctga tgccgtggcg caaagggccg ttctcactgt
     7381 atggcgtcaa catcgatacc gaatggcgtt ccgactggaa atgggatcgt gttctgcccc
     7441 atctttctga tttaaccgga cgcaccattc tggatgtcgg ctgcggcagc ggttatcaca
     7501 tgtggcgcat gattggcgca ggcgcgcacc tcgcggtggg gatcgaccct acgcaactgt
     7561 ttctgtgcca gtttgaagcg gtgcgtaaac tactgggtaa tgatcagcgc gcgcatttgt
     7621 taccgttagg tattgaacaa cttccggcac tgaaagcctt tgataccgtc ttttcgatgg
     7681 gcgtgcttta ccatcgccgt tcaccgctgg agcatctatg gcagttgaaa gatcaactgg
     7741 tcaataaagg tgaactggtg ctggaaacgc tggttattga tggtgatgag aacacggtgc
     7801 tggtaccagg cgatcgttac gcgcaaatgc gtaatgtcta tttcatccct tccgcgctgg
     7861 cgctgaaaaa ctggctgaag aagtgtggtt ttgtagatat ccgcattgcg gatgtgagcg
     7921 ttaccaccac agaagagcag cgacgcaccg aatggatggt taccgaatcg ctggccgatt
     7981 tcctcgaccc acatgatccg ggtaaaacgg tggaaggtta tccggcacct aaacgcgcgg
     8041 tgctgattgc gcgcaagccg taaaggtctg gtattactgc cggatgcggc gtgaactcct
     8101 tatccggcct acaaaacctt gctaattcaa tatattgcag ggactatgta ggcctgataa
     8161 gcatagcgca tcaggcagct ttacgtttgc ataacctcag cgcccgtttc cgggcgctat
     8221 tcacgtctta cgcctgaaca gctggctgat caaacgccgt taacttcggt gcattgcccg
     8281 tatatttttc gatatacacc aacgctgagt taccggcaca ggcatttgcc agctgcgagc
     8341 tggggatatc cgccgttaac acgttcgcac tgccgttttt acacaagcca ttttccagat
     8401 ctggccatgc accttcatgc acgcatacca cgcctttttt gatcccgtca gtcaccaccg
     8461 cgcctgtcaa aatctgacca cgtttgttcc agacacgcac cagatcgcca ttcgcaatac
     8521 caaagcgtgc agcatcttcg gtgtgaatag tgattggttc acgatctgca accgcatatt
     8581 ttttacgcag ttccgcatag ttaagctgac tatgtaaacg gtgtgccgga tgtgcggtca
     8641 gaagctgcaa ctgcttctcg tcggcggtac ccttccactc atcaggcgca agccaggttg
     8701 ggtgtgccgg gcaatcctta tagccaaatt tttccagcgt tttggagtaa atctcaattt
     8761 tgccgcttgg cgtacccagc gcatttttca ccggatcggc gcggaaatca ccataacgaa
     8821 cgtactgttc gttcttctcg ctgcggcgca tttcgatcag tttattttgc tgccagaagg
     8881 cattaaacat cggcatagtc acgcgttgcg cacgggcacc tttctgagcg gcatcataga
     8941 aaaatttcag ccacgccatt tcatctttac cttcggtata gatctctttt ccgccaggtt
     9001 tcagtaattc cgcaagatcg gcaaacacat caaaatcgtt tcgcgcttca aattgcggag
     9061 cgacagcctg cttcatcggc acaatatgct ggttgctgta atcaccggtc atcgtcaagt
     9121 cattgcgctc aaacgatgtg gtgatcggta atacgatatc tgcatgttta gcagctgcgg
     9181 tccagtagca ttcagaaacg acgatcatct ccggtttctg ccatgcttta atcagacgat
     9241 tagtatcctg gtgatgggta aagttaccgc cacccgccca ccagatcatt ttgatattcg
     9301 gatacgtttg ctctttaccg ttatgctgat atttgccgcc aggattttcc agcgcatcga
     9361 cgatacgggc aacaggaatc gccgtcattc cgccatcatc agcggcctcg ctggcctgtc
     9421 cggcaatagc cgcagacatt tccggcagca cgccgccaac acgtgtcggg ttgccaccat
     9481 tggagtaatg ataagagaaa ccaaaaccgc cgcccggtgt accaatctgc cctaacatcg
     9541 ccgccagcgt caccagcatc cagtgtttct gttcaccata ttgctggcgc tgaattcccc
     9601 agcctgccat cagcattgtg cgattcgccg ccatcagttc agcgagtttg actatctgcg
     9661 cttccggtac gccagtaatt tccgccgccc aggccgcgct cttcggagta ttatcgctct
     9721 tacctgtcag atattcttca aactgcggat acccggtggt gtatttttca aggaacactt
     9781 tatcgtgttt gccttgtgtc atcagggtat gcgcaatccc taacatcagt gccacgtcgg
     9841 tgcccatatt cggcgcgatc caggtggcat tatcgccaaa gaactcaatg gtttcggagc
     9901 ggataggatc aatggcaatc actggtttgc cagatttttt cagctgatgg aagtattcca
     9961 gcccttgctc atcggtactg ctccaggcaa tttttaaggt attcagcggg ttcatccccc
    10021 acagcaccac aacctggctg ttttccagaa tcagcggcca ggaggtctgc tgttcataca
    10081 cctctacaga accgaccaca tgcggcatga tcacctgtgc tgccccggtt gaataatcgc
    10141 cgctatgccc ggaataaccg cccgcgaggt tcatataacg ttgcagtaag gtttgcgctt
    10201 tatgcaacac gccagaagag cgccagccgt aagatccggc aaaaatggcc gatggtccgt
    10261 tagctttacg aatacgatcg tgttgctcat gaatcagttt taatgcttgt tcccagctca
    10321 cctgtacata ggtatcttcg cctcgacctt tcgccggttg cagtggatta tcgagatagc
    10381 tttttctcac catcggatgc tgaatacgcg ccgtggtgtg tacctgatcc gccgccgtag
    10441 actgtaagga gttcggtatg gttttcgcca gcgcgcctgt cgaagaaaca atcttgccgt
    10501 ccttcacttc tacgttcatc gctccccagc gtcccgcggt gaggatttta ccgcccttct
    10561 cttctgccca tgcgggtagc ggtgctgccg atgtcaccac cagcgctcca gcggcaatac
    10621 cgctgtgttt aataaattca cgtcttgtta atgtcataac ttcctccctg atcaacgagg
    10681 atcactgttt ctcggtaata tctttggcgt tgtactggaa ataccgcgtt aaaatgtcca
    10741 gttcgttttc gctcatgctg gttcgtgccc ccattccttt ggcaatggac ggccacgcat
    10801 tgacggtgta atggtcggcg gcaatagggg catgacaacc agcgcaatag gtatcgtcaa
    10861 gtttttcagc gtattgccat agcggtttac ggtccgctaa tgcgggatcg gtaagcgcac
    10921 cctgtaaaga cgcctgacgc cattgattgc cgtattcgtc agcctgccat tccccgttta
    10981 ccgtgagcgc cttgatacct tcttcactta atgtggctag cgccagccgt tgacctgccg
    11041 ccaggtagag cgtgttttca ctgccctgca tttgataacc ctgcaacaga acgatcggct
    11101 gtttgccact ggcatcaacg acggtgagat cggtaccagg attcacggta gccagctcgc
    11161 ctatgcgaga agttttgaaa ggataaatat gtgcgccatt agtcactgaa gtagcggtct
    11221 gactttccag ctcatgcgcc gcgttgtcat ccatttttat ttctggcgga aaatgggcaa
    11281 tgcctttatg acaatcgata caggtttcgc cgcccttttg tgctttgtta tgcattttct
    11341 gcgcagattc actttgcgag gcaatatcca tggcatcaaa agaatggcaa ctacggcacg
    11401 ttgcagagtc agttgctttt aattctttcc atactgtttc ggccatttcc tggcgatgag
    11461 tttcgaactt atcgtcactg tctattttgc cgctaacaaa ttcatgataa atatctttag
    11521 atgcttttaa tttagcaaat aaataatcca tccctgactt tggaatatgg caatcggcac
    11581 attccgcacg tatccctttc tggttcgaaa agtggacagt tccctgatat tcctcaaaag
    11641 gtttactcat cgagtggcag gaaaggcaaa atgctgtatc cgacgtttta tgtaaggctt
    11701 tttgcgccag caataacccg ccgccaccaa ccacaaccgc tatcagcaaa aacaataacc
    11761 caatgcgttt tttccctcgc atagattcct ctaaataaat tccagaacac cgaaatcatt
    11821 gtataattaa atacacaacg aattaaccgc
//
LOCUS       DAPGUL010000135        11847 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.138, whole genome shotgun sequence.
ACCESSION   DAPGUL010000135 DAPGUL010000000
VERSION     DAPGUL010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11847)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11847)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11847
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.138"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(112..393)
                     /locus_tag="RHX21_003971"
     CDS             complement(112..393)
                     /locus_tag="RHX21_003971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YehE family protein"
                     /protein_id="HDV1989090.1"
                     /translation="MNKYWLSGIIFLAYGLASPAFSSETATLTINGRISPPTCSMAMV
                     NSQPQQHCGQLTYNVDTRHQVSSPVKGVTTEVVVAGSDSKRRIVLNRYD"
     gene            complement(656..1765)
                     /gene="apbC"
                     /locus_tag="RHX21_003972"
     CDS             complement(656..1765)
                     /gene="apbC"
                     /locus_tag="RHX21_003972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310946.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster carrier protein ApbC"
                     /protein_id="HDV1989091.1"
                     /translation="MNEQSQAKSPEALRAMVAGTLANFQHPTLKHNLTTLKALHHVAW
                     MDDTLHVELVMPFVWHSAFEELKEQCSAELLRITGAKAIDWKLSHNIATLKRVKNQPG
                     INGVKNIIAVSSGKGGVGKSSTAVNLALALAAEGAKVGILDADIYGPSIPTMLGAENQ
                     RPTSPDGTHMAPIMSHGLATNSIGYLVTDDNAMVWRGPMASKALMQMLQETLWPDLDY
                     LVLDMPPGTGDIQLTLAQNIPVTGAVVVTTPQDIALIDAKKGIVMFEKVEVPVLGIVE
                     NMSVHICSNCGHHEPIFGTGGAEKLAEKYHTQLLGQMPLHISLREDLDKGTPTVISRP
                     ESEFTAIYRQLADRVAAQLYWQGEVIPGEISFRAV"
     gene            1897..3930
                     /gene="metG"
                     /locus_tag="RHX21_003973"
     CDS             1897..3930
                     /gene="metG"
                     /locus_tag="RHX21_003973"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HDV1989092.1"
                     /translation="MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGH
                     EVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEE
                     NRQLSELIYSRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCE
                     VCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANK
                     MQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSV
                     SFDEYWKKDSTAELYHFIGKDIVYFHSLFWPAMLEGSNFRKPTNLFVHGYVTVNGAKM
                     SKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVN
                     LASRNAGFINKRFDGVLASELADPQLYKTFTDAAEVIGEAWESREFGKAVREIMALAD
                     LANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLN
                     TELTWDGIQQPLLGHKVNPFKALYNRIDMKQVEALVEASKEEVKAAAAPVTGPLADDP
                     IQETITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQ
                     ALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDAGAKPGHQVK"
     gene            4071..7865
                     /locus_tag="RHX21_003974"
     CDS             4071..7865
                     /locus_tag="RHX21_003974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001215568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WGR and DUF4132 domain-containing protein"
                     /protein_id="HDV1989093.1"
                     /translation="MRHFIYQDEKSHKFWAVEQQDNELHISWGKIGTHGQSQIKSFSD
                     AAAAAKAELKLIAEKVKKGYVEQAKDNSLQPSQTVTGSLKVADLSTIIQEQPSFVAET
                     RAPDKNTDAVLPWLAKDIAVVFPPEVVHTTLSHRRFPGVPVQQADKLTQLRRLACSVS
                     QRDNKTATFDFSACSLEWQNTVAQAISQIDGLKTTQLPSPVMAVLTALEMKCTRYKVR
                     EDVMDQIVQEGGLEYATDVIIHLQQIDIEWDYANNVIIILPSGIAPSYLEQYSRFELR
                     LRKHLSLTEESLWQKCAQKLIAAIPHIPEWRQPLIALLLPEKPEIAHEIAQRLLGQKK
                     LPSLEWLKIVATDEHILASLEKYHEPYAIFDDYYCGAIWSATVLQEQGVAALPRFAPY
                     AASDYCADVLRHINHPFALTLLIRVAGHTKRCHDRMTKAIAAFPHAAMAALTELLGQK
                     EENSWRIMLMTMLISQPALAEQVIPWLSTPAVAVLKSCQQQLTQPSNHASADLLPAVV
                     VSPPWLSKKKKSPIPVLDLAPLGIEPICYLTEEISNQLLAKYIWYSKHITVSHEESTT
                     NLLARMGFQRRIAGTYIKAPEAVVEAWLNEDYSTLLSEFKVFHSPTGHYWQLGILTTL
                     PLEKAVKAWNALTLSPHTDTEYAMLHFGLKGLPGLVNSLARYPQEALPITNYFAASEL
                     APAVARAFNKLKTLRENARSWLLKYPEHALTGLLPAALGKAGEAQDNARAALRMLTEN
                     GHQPLLQEIARRYNQPEVTDAVNALLALDPLDNHPTKIPTLPAFYQPSLWTRPVLKAN
                     AQSLPDSALLHLGEMLRFPQEEALYPGLLQVKDVCSADSLAGFAWDLFTAWQTAGAPS
                     KESWAFTALGVLGNDDTARKLTPLIRAWPGESQHKRATVGLDILAAIGSDIALMQLNG
                     IAQKLKFKALQERAKEKIADIAESRELTVAELEDRLAPDLGLDDNGSLLLDFGPRQFT
                     VSFDETLKPFVRDVSGSRLKDLPKPNKSDDETRANDAVNRYKLLKKDARTIAAQQVAR
                     LESAMCLRRRWSLENFQLFLVEHPLVRHLTRRLIWGVYSAENQLLACFRVAEDNSYST
                     ADDDLFTLPEGDISIGTPHVLEISPTDAAAFGQLFADYELLPPFRQLDRNSYALTEAE
                     RNASELTRWAGRKCPSGRVMGLANKGWIKGEPQDGGWIGWMIKPLGRWSLIMEIDEGF
                     AVGMSPAELSAEQLLSKLWLWEGKAESYGWGSNSTQEAQFSVLDAITASELINDIEAL
                     FE"
     gene            7875..11507
                     /locus_tag="RHX21_003975"
     CDS             7875..11507
                     /locus_tag="RHX21_003975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HDV1989094.1"
                     /translation="MDKELPWLADNAQLELKYKKGKTPLSHRKWPDEPVPVITESIIQ
                     TLGDKLLQKAEKKKNIVWRYENFSLEWQSAITQAINLIGEHKPSIPARTMAALVCIAQ
                     NDSQQLLDEIVQQEGLEYATEVVIARQFITRCYESDPLLVTLQYQDEDYGYGYRSETY
                     NEFDLRLRKHLSLAEESSWQRCADKLIAALPGIPKIRRPFIALLLPEKPEIANELASL
                     ESSRSSLHSKEWLKVIATDNTAVKKLERYWGLDVFSDREASYMSQENRFGYAACASLL
                     REQGLAAVPRLAMYAHKEDCGSLLVQINHPQVIRTLLLVADKNKPSLQRVAKYSKNFP
                     HATLAALAELLALKEPPARPGYPIIEDKKLPAQQKARDEYWRTLLQTLMASQPQLAAE
                     VMPWLSTQARAVLNSYLSAPPKPVIDSTDNSSLPEMLVSPPWRSKKKMTAPRLDLAPL
                     ELTPQIYWQPGEQERLAATESARYFSTESLAERMEQKSGRVVLQELGFGDDVWLFLNY
                     ILPGKLDAARNSLIVQWHYYQGRVEEILNGWNSPQAQLAEQALRSGHIEALINIWEND
                     NFSRYRPEKSVWNLYLLAQLPREMALTFWLRIIEKKHLFAGEDYFLSILGLDALLGLL
                     LAFSHRPKETFPLILNFGATELALPVARVWRRFAAQRDLARQWILQWPEHTASALIPL
                     VFTKPSDNSEAALLALRLLYEQGHGELLQTVANRWQRTDVWSALEQLLKQGPMDIYPA
                     RIPKAPDFWHPAMWSRPRLITNNQPVTGDALEIIGEMLRFTQGGRFYSGLEQLKTFCQ
                     PQTLAAFAWDLFTAWQQAGAPAKDNWAFLALSLFGDESTARDLTTQILAWPQEGKSAR
                     AVSGLNILTLMNNDMALIQLHHISQRAKSRPLRDNAAEFLQVVAENRGLSQEELADRL
                     VPTLGLDDPQALSFDFGPRQFTVRFDENLNPVIFDQQNVRQKSVPRLRADDDQLKAPE
                     ALARLKGLKKDATQVSKNLLPRLEAALRTTRRWSLADFHTLFVNHPFTRLVTQRLIWG
                     VYPANEPRRLLNAFRVAAEGEFCNAQDEPIDLPADALIGIAHPLEMTAEMRSEFAQLF
                     ADYEIIPPLRQLTRRTVLLTPDESASNSLNRWEGKSATVGQLMGMRYKGWESGYEDAF
                     VYDLGEYRLVLKFSPGFNHYNVDSKALMSFRSLRVYSDNKSVTFAELDVFDLSEALSA
                     PDVIFH"
     gene            11568..>11847
                     /locus_tag="RHX21_003976"
     CDS             11568..>11847
                     /locus_tag="RHX21_003976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989095.1"
                     /translation="MIVQKELVAIYDYEVPVPEDPFSFRLEIHKCSELFTGSVYRLER
                     FRLRPTFHQRDREDADPLINDALIYIRDECIDERKLRGESPETVIAIFN"
BASE COUNT         3098 a         3010 c         2918 g         2821 t
ORIGIN      
        1 ttaattaatg tagatttatg taaatggtat tgttgatatc aataaaaaag ccgatatcat
       61 ttatataaat gatttcggct ttctaaatgc aattaaaatc aggttgccaa attaatcgta
      121 gcgatttaac acgattcgac gtttgctatc gctacctgca acaaccactt ctgtcgtaac
      181 acctttgacg ggcgaagaaa cctgatgacg ggtgtcaaca ttatacgtta actgaccaca
      241 atgctgttgt ggttgactat taaccatagc catactgcat gttgggggac tgatcctgcc
      301 attaatcgtt aatgtggcag tctctgaaga gaatgcggga gaagccaatc cataggcaag
      361 aaaaataatt cctgacagcc aatacttatt cattgaacgt tatccctgta gtaaaggtta
      421 tgcctggata gaatgagtgc ataacaaact atagctgtac atccactaca cagccacgaa
      481 ggatgataat gaagcattgc ctgtatgatc aatcgacttt gtagagtttc ggacgaaggt
      541 ccgcagaata ttcgcagtat taaataagtg ttcattaatg cggcaaaaac taatacaccg
      601 catcaatgta acatctctgc ggtgtatgaa gaataaccag aatggttaat aggcgttaga
      661 ccgcgcggaa ggaaatctcg cctggaatga cttcaccctg ccagtagagc tgagctgcaa
      721 cgcggtcagc cagctggcgg tagatagcgg taaattcgct ctccggacgg ctgataaccg
      781 ttggcgtgcc tttatcgaga tcctcacgta aggaaatgtg taacggcatc tgccccagca
      841 gctgtgtgtg gtatttttca gccagtttct ctgcaccacc ggtaccgaaa atcggttcat
      901 ggtgaccaca gttactgcaa atatgcacac tcatgttctc gacaatacca agcaccggaa
      961 cctcgacttt ctcgaacatc acaatgcctt ttttcgcatc gatcaacgcg atgtcctgcg
     1021 gggtggtgac cacgactgca ccagttactg gaatgttttg cgccagcgtc aattgaatgt
     1081 caccggtgcc tggcggcata tcaagcacca gatagtcgag atccggccac aaggtttcct
     1141 gcaacatctg cattaacgcc ttgctcgcca tcggtccacg ccacaccatc gcattgtcgt
     1201 cagtgaccag ataaccaatt gaattggttg ccaggccatg agacataatc ggtgccatat
     1261 gggtaccgtc cggcgaagtt ggacgctgat tttctgcgcc cagcatggtg ggaattgatg
     1321 ggccgtagat atcggcgtcc agaatgccga ctttcgcccc ttccgccgcc agtgccagcg
     1381 ccaggtttac cgccgtggag gatttaccca cgccgccttt accggaactg accgcaatga
     1441 tgttcttcac accattaata cccggctgat tcttcacgcg ttttaaggtg gcgatattgt
     1501 gcgacagttt ccagtcgata gctttcgccc cggtgatacg cagcagttcg gcgctacatt
     1561 gctcttttaa ctcttcaaac gcgctatgcc agacgaatgg cataaccagt tccacatgca
     1621 acgtgtcgtc catccaggcg acatggtgca acgctttcag cgtggtgagg ttatgcttca
     1681 gggttgggtg ctgaaaattg gccagtgtcc cggcgaccat tgcgcgcaag gcttctggtg
     1741 atttggcctg ggattgttcg ttcatcccga ctcctttttt gtatagataa accatcagct
     1801 gatagtttac ctgaagaata tagagaagta cttacttaac attttcccat ttggtactat
     1861 ctaacccctt ttcactatta agaagtaatg cctactatga ctcaagtcgc gaagaaaatt
     1921 ctggtgacgt gcgcactgcc gtacgctaac ggctcaatcc acctcggcca tatgctggag
     1981 cacatccagg ctgatgtctg ggtccgttac cagcgaatgc gcggccacga ggtcaacttc
     2041 atctgcgccg acgatgccca cggtacaccg atcatgctga aagctcagca gcttggtatc
     2101 accccggagc agatgattgg cgaaatgagt caggagcatc agactgattt cgcaggcttt
     2161 aacatcagct atgacaacta tcactcgacg cacagcgaag agaaccgcca gttgtcagaa
     2221 cttatctact ctcgcctgaa agagaacggt tttattaaaa accgcaccat ctctcagctg
     2281 tacgatccgg aaaaaggcat gttcctgccg gaccgttttg tgaaaggcac ctgcccgaaa
     2341 tgtaaatccc cggatcaata cggcgataac tgcgaagtct gcggcgcgac ctacagcccg
     2401 actgaattga tcgagccgaa atcggtggtt tctggcgcta cgccggtaat gcgtgattct
     2461 gaacacttct tctttgatct gccctctttc agcgaaatgt tgcaggcatg gacccgcagc
     2521 ggtgcgttgc aggagcaggt ggcaaataaa atgcaggagt ggtttgaatc cggcctgcaa
     2581 cagtgggata tctcccgcga cgcgccatac tttggttttg aaattccgaa cgcgccgggc
     2641 aaatatttct acgtctggct ggacgcaccg attggctaca tgggttcttt caagaatctg
     2701 tgcgacaagc gcggcgacag cgtaagcttc gatgaatact ggaagaaaga ctccaccgcc
     2761 gagctgtacc acttcatcgg taaagatatt gtttacttcc acagcctgtt ctggcctgcc
     2821 atgctggaag gcagcaactt ccgcaagccg accaacctgt ttgttcatgg ctatgtgacg
     2881 gtgaacggcg caaagatgtc caagtctcgc ggcaccttta ttaaagccag cacctggctg
     2941 aatcattttg acgctgacag cctgcgttac tactacactg cgaaactctc ttcgcgcatt
     3001 gatgatatcg atctcaacct ggaggatttc gttcagcgtg tgaatgccga tatcgtgaac
     3061 aaagtggtta acctggcctc tcgtaatgcg ggctttatca acaagcgttt tgacggcgtg
     3121 ctggcaagcg aactggctga cccgcagttg tacaaaacct tcactgatgc cgctgaagtg
     3181 attggtgaag cgtgggaaag ccgcgaattt ggtaaagcag tgcgcgaaat catggcgctg
     3241 gctgatctgg ctaaccgcta tgtcgacgag caggctccgt gggtggtggc aaaacaggaa
     3301 ggccgcgatg ccgacctgca ggcaatttgc tcaatgggca taaacctgtt ccgcgtgctg
     3361 atgacttacc tgaagccggt actgccgaaa ctgaccgagc gcgcagaagc attcctcaat
     3421 acagaactga cctgggatgg tatccagcaa ccgctgctgg gccacaaagt gaatccgttc
     3481 aaagcgctgt ataaccgcat cgatatgaag caggttgaag cactggtgga agcgtctaaa
     3541 gaagaagtga aagcagctgc cgcgccagtt actggcccac tggcagatga tccgattcag
     3601 gaaaccatca cctttgacga cttcgcaaaa gttgacctgc gcgtggcgct gatcgaaaac
     3661 gcagagtttg ttgaaggttc tgacaaactg ctgcgcctga cactggatct cggcggtgaa
     3721 aaacgcaatg tcttctccgg tattcgttct gcctacccgg atccgcaggc actgatcggg
     3781 cgtcacacca ttatggtggc caacctggca ccgcgtaaaa tgcgctttgg tatctccgaa
     3841 ggcatggtaa tggctgctgg tcctggcggg aaagatatct tcctgttaag cccggatgct
     3901 ggtgctaaac caggccatca ggtgaaataa tcccccttta aggcgctgca tcgacagcgc
     3961 cttttcttta taaattccta aagttgtttt cttgcgattt tgtctctctc taacccgcat
     4021 aaatactggt agcatctgca ttcaactgga taaaattaca gggatgcaga atgagacact
     4081 ttatctatca ggacgaaaaa tcacataaat tctgggcagt tgagcaacag gataatgagc
     4141 ttcatattag ctggggcaaa atcggtaccc acggacaaag tcagataaaa agtttttcag
     4201 atgctgcggc agcggcaaaa gcggagctta agctgattgc ggagaaggtg aagaaggggt
     4261 atgtggagca agcgaaggat aattctttgc aaccttccca aacggtaacg ggctctctca
     4321 aggtagcgga cttatccacc attattcagg aacaaccctc tttcgtagca gaaacccgtg
     4381 cgcctgacaa aaatacagat gctgttttac cgtggctggc gaaagatatt gctgtcgttt
     4441 ttccgcccga agttgtacac accacgttaa gtcatcgccg ctttcccgga gttcctgttc
     4501 agcaagcaga caaattgacc caattacgtc gcttagcctg tagtgtgtcg caacgggata
     4561 ataaaacagc cacatttgac ttcagcgcct gttctttaga atggcaaaac accgtcgccc
     4621 aggcgatcag tcagatcgac ggcctgaaaa caacacagtt accatcacca gtaatggctg
     4681 tactcacggc acttgaaatg aaatgcacaa gatataaagt gcgtgaggat gttatggatc
     4741 agatcgtcca ggaaggcggt ctggaatatg ctactgatgt aataatacac cttcaacaga
     4801 ttgatattga atgggattat gcgaataatg tcattattat tctgccgtct ggcattgcac
     4861 ctagctactt ggagcaatat tccagatttg aattacgcct acgtaaacat ttatcactga
     4921 cggaagagtc tctctggcaa aaatgtgcac aaaaacttat tgccgcaatt ccacatattc
     4981 cagaatggcg gcaaccatta attgctttgt tattacccga aaaaccagaa attgcacatg
     5041 aaattgccca gcgtctactg gggcaaaaaa aattaccctc gcttgagtgg ttaaaaatag
     5101 tggcgactga tgagcacatt cttgcctcat tagaaaaata tcacgaacca tatgccattt
     5161 ttgatgatta ctattgtggt gcgatatggt cagccaccgt attacaggag caaggtgttg
     5221 cagccctgcc ccgatttgct ccctatgccg caagtgacta ctgcgccgat gtgttgcgtc
     5281 atatcaatca tccgttcgca ttaacactgc ttatacgtgt agccgggcat actaaacgct
     5341 gtcacgatcg gatgacgaaa gccattgctg cgttcccaca tgcagcaatg gcggcactga
     5401 cggaacttct tgggcaaaaa gaagagaaca gttggcgcat tatgctaatg acaatgctta
     5461 tctcacaacc agcactggca gaacaggtca ttccctggct ctcgacaccc gcagttgccg
     5521 tactgaaatc atgccagcaa caactgacac agccctcaaa ccatgccagc gccgatctac
     5581 tgccagccgt agtagtctcc cctccctggc tttcgaaaaa gaaaaaatcg ccgattccgg
     5641 tgctggattt agcgccatta ggcattgagc caatctgtta tctgacagaa gaaatcagta
     5701 atcaactttt ggcgaaatat atctggtatt caaaacacat cacggttagc catgaagaaa
     5761 gtactaccaa cctgttggca aggatgggtt ttcaacgacg gatcgctggt acatatatta
     5821 aagctcccga agcggtagtt gaggcatggc taaatgaaga ttattcaacc ttactaagtg
     5881 aatttaaggt gtttcattca cctaccgggc attattggca gttggggatt ttgacaacat
     5941 tgccgctgga gaaagcagta aaagcatgga atgcccttac cctatctcca cataccgata
     6001 ccgaatacgc catgttacat tttggactca aagggttacc tgggttagta aactcacttg
     6061 cacgctatcc acaagaagcc ttgcccatca cgaattactt cgcagcgagt gagctggctc
     6121 ctgccgtcgc ccgtgccttc aacaaactga aaacgctacg cgaaaacgcc cgtagctggc
     6181 tgttgaaata cccggaacat gcccttaccg gcctgctgcc tgcggcgctc ggcaaagccg
     6241 gtgaagcaca ggataacgcc cgcgctgcct tgcgtatgct taccgaaaac ggtcatcagc
     6301 cattactgca agaaatcgcc cgacgttata accagccgga agtaaccgat gcggtgaacg
     6361 ctctgcttgc gctcgatccc ttagataatc acccgacaaa aatccccact cttccggcct
     6421 tttatcagcc atcgctctgg acgcgcccgg tattaaaagc aaatgcccaa tcactgccag
     6481 atagcgccct cctccacctc ggtgaaatgc tccgcttccc tcaggaagag gctctgtatc
     6541 cgggattatt gcaggtgaaa gacgtctgtt ccgccgactc actggcggga tttgcctggg
     6601 atctgtttac cgcctggcag accgctggcg cgccgtcgaa agagagttgg gcgttcactg
     6661 cgttaggcgt tctcggtaac gatgacaccg cccgcaaact gacgccatta atacgcgcct
     6721 ggcctggtga atcccagcat aaacgcgcca ccgttgggtt ggatattctc gctgctatcg
     6781 gtagtgatat cgcccttatg cagcttaacg gcatcgccca gaaactgaaa ttcaaagcat
     6841 tacaggagcg ggcaaaagaa aaaattgccg acattgccga gagccgcgaa ctcacggtgg
     6901 cggagcttga agatcggtta gcaccggatc tcggtctgga tgataacggt tcgctgctgc
     6961 tggattttgg cccacggcag ttcaccgtca gctttgatga aaccttaaaa ccgtttgtgc
     7021 gtgatgtttc cggcagccgc ctgaaagacc tgcccaaacc gaacaaaagc gatgatgaaa
     7081 cgcgggcgaa cgatgcggtt aaccgctaca aattgctgaa aaaagatgcg cgtaccatcg
     7141 ccgcccagca ggtagcaagg ctggaatccg ccatgtgcct gcgccgccgc tggtcgctgg
     7201 aaaacttcca gctcttcctg gttgagcatc cgctggttcg tcacttaacc cgccgtctga
     7261 tttggggcgt ttatagcgcc gaaaaccagc tactggcttg ctttcgcgta gcagaagata
     7321 acagctacag caccgctgac gatgatcttt tcaccctgcc ggaaggcgat atctctatcg
     7381 gcactcctca cgttctggaa atatcaccaa cggatgctgc cgcctttggt cagctttttg
     7441 ccgactacga actgctacca ccgttccgcc agctcgaccg taacagctac gccctgacag
     7501 aagccgagcg caatgccagt gaactgaccc gctgggcagg cagaaaatgc ccgagtggtc
     7561 gggtcatggg gctggcgaat aaaggctgga taaagggcga accacaggat ggaggctgga
     7621 tcggatggat gatcaaacct ttgggtcgct ggtcgttaat catggaaatc gacgaaggtt
     7681 ttgcggtggg tatgtcacca gccgaactta gcgctgagca gctcttaagc aagctgtggt
     7741 tatgggaagg caaagcggaa agctatggct gggggagtaa ttcaacacag gaagcgcagt
     7801 tctccgtact cgatgccatc accgccagcg agctaattaa cgatattgaa gccctgtttg
     7861 aataaggaaa gagcatggac aaggaattac cgtggctggc ggataacgcc caactggaac
     7921 tgaaatataa aaaaggcaaa acaccactca gtcatcgcaa atggccggac gaaccggtgc
     7981 ctgttatcac tgaaagcatc attcagacac tgggtgataa attgctacaa aaagctgaga
     8041 agaaaaaaaa cattgtctgg cgttatgaaa atttttcact ggagtggcag tccgccatca
     8101 cgcaggccat caacttgatc ggcgaacaca aaccctcaat cccggcccgg acaatggcgg
     8161 cgctagtctg tatcgcgcaa aatgacagcc aacagttgct cgacgaaatc gtccaacaag
     8221 agggactgga atatgcgact gaggtggtga ttgcacgcca gtttattaca cgatgttatg
     8281 agagtgatcc tctgctagtg acattgcagt atcaggacga ggattatggc tatggttatc
     8341 gctcagaaac ctataacgaa ttcgatctcc gactgcgtaa gcatctctct ctggcagagg
     8401 aaagcagctg gcagcgttgc gccgacaaac tcattgccgc actgccagga atacccaaaa
     8461 ttcgccgtcc ttttattgca ctactcctcc cggaaaaacc tgaaatagcc aatgaactcg
     8521 ccagtcttga aagctcccgg tcaagtctcc attcaaagga gtggttaaag gtcattgcta
     8581 ctgataatac ggcggtaaaa aaactcgaac gatactgggg cctggacgta tttagcgatc
     8641 gcgaagccag ctacatgtca caagaaaacc gcttcggcta cgcggcctgc gcctcccttt
     8701 tgcgcgaaca aggactggca gccgttccgc gcctggcaat gtatgcccat aaagaagatt
     8761 gcggcagtct gctggtacaa attaaccatc cgcaagtcat ccgcaccttg ctactggtgg
     8821 ctgataaaaa caaacccagc ctgcaacgtg tggctaaata cagtaaaaac ttcccccacg
     8881 cgacgctcgc cgcactggca gaactgctgg cgttaaaaga accaccagcc cgcccaggtt
     8941 atccaatcat cgaagacaaa aagctgcctg cacagcaaaa agcacgcgat gaatactggc
     9001 gtacgctgtt acaaacgctg atggcatcgc agccacaact ggcagcagaa gtgatgccgt
     9061 ggttaagtac tcaagccagg gcagtgctga atagttattt atcggcaccg ccaaaaccgg
     9121 ttattgatag caccgataac agcagtctgc ctgaaatgct cgtttcacca ccgtggcgta
     9181 gtaagaaaaa aatgacagct ccacgtcttg atttggcacc gctcgaatta actccgcaaa
     9241 tttactggca accaggcgaa caagagaggc ttgccgccac tgagtctgcc cgttatttca
     9301 gcacggaatc tcttgcggaa cgcatggaac aaaaaagtgg acgagttgta ttacaggaac
     9361 tgggttttgg ggatgatgta tggctgtttc tgaattatat actccccgga aaactggatg
     9421 ctgcacgcaa ttcactcatt gttcagtggc attactacca ggggcgggtt gaagagatcc
     9481 tgaatggctg gaactccccg caagcacaat tagcagaaca ggcgctccgc agcggtcaca
     9541 tagaagcgtt aattaacata tgggaaaatg acaacttctc acgttatcgt ccggaaaaga
     9601 gtgtctggaa cctgtattta ttggcacagt tgccgcgtga gatggctttg accttctggc
     9661 tgcgtatcat tgagaaaaag catctgttcg cgggtgagga ctattttctc agtatcctcg
     9721 gattggatgc gctactaggt ctgctgttgg ctttttcaca tcgtccaaaa gaaacatttc
     9781 cgttaatttt aaattttggc gcaacagaac tggcgctgcc tgttgcccgc gtctggcgac
     9841 gtttcgcggc gcagcgtgat ctggctcgcc agtggatttt acaatggccg gaacatacgg
     9901 ctagtgcact tatccctctt gtctttacca aacccagcga taatagcgaa gccgcattac
     9961 ttgccctgcg tttactgtac gaacagggac atggcgaatt gctacaaacc gtggcaaacc
    10021 gctggcagcg tacagatgta tggtctgccc tggagcagtt gcttaaacag ggtccaatgg
    10081 acatttaccc ggcacgcatt ccaaaagccc ctgatttctg gcatccggca atgtggtcca
    10141 ggcctcgact tatcactaat aatcagcctg ttaccggtga cgctctggaa attatcggcg
    10201 aaatgctgcg ctttacccag gggggacgtt tttatagcgg gctggaacaa ctgaaaacgt
    10261 tctgccagcc acaaacgctg gcagcttttg cctgggatct cttcactgcg tggcaacaag
    10321 ctggtgcccc cgcaaaagac aactgggcat ttctggcgtt aagtctcttt ggtgacgaaa
    10381 gcacggcacg ggatctgacg acacagatcc tcgcctggcc acaagaaggc aaatctgccc
    10441 gtgctgtcag cggcctgaac atccttaccc tgatgaataa tgatatggcg ctgatacagc
    10501 tgcatcatat atcgcaacgg gctaaatccc gccccttacg tgataacgcg gcggaatttc
    10561 ttcaggtggt cgcagaaaat cgcgggctaa gccaggaaga gctagcggac agattagtcc
    10621 caaccctggg ccttgatgat ccgcaggcgt tgagttttga ttttggtccc cggcagttta
    10681 ccgttcgctt cgatgaaaac ctcaacccgg ttatctttga tcagcaaaac gttcgccaga
    10741 aaagcgttcc ccggttgcgc gccgatgacg atcaactgaa agcgcccgag gcactggccc
    10801 gactaaaagg gctaaaaaaa gatgctactc aggtgagcaa aaacctgctc ccgcgtcttg
    10861 aagctgccct acgtaccacc cgacgctggt cgctggcaga ttttcatact ctgtttgtta
    10921 atcatccctt tacccgcctg gttacccagc gattaatatg gggcgtgtat ccggcaaatg
    10981 aaccgcgtcg tttactcaac gcctttcgtg tggccgcaga gggggagttc tgcaatgcgc
    11041 aggatgagcc aattgacctg cctgcggatg ctctgattgg cattgcccac ccgttagaaa
    11101 tgacagcaga aatgcgcagt gaatttgccc agctttttgc cgattacgaa attataccgc
    11161 cacttcgcca gttgacacgg cgcacggtgc tgctcacgcc tgacgagtca gccagtaata
    11221 gtttgaatcg ctgggaaggt aaatctgcta ccgttgggca acttatggga atgcgataca
    11281 aaggctggga gtcaggctat gaggacgcat ttgtctatga cctgggtgag taccggctgg
    11341 tccttaagtt ttcacccggt tttaaccact acaatgttga tagcaaagcg ctaatgagct
    11401 tccgttctct tcgagtgtac agtgacaata aatccgtcac ttttgccgaa cttgatgtgt
    11461 ttgatttgag tgaggcgtta agcgcacctg acgtcatttt ccattaaaac acagcgggca
    11521 gtgatgcaac tgcccgttat caacacgact taccagcggg gaaagcgatg atcgtgcaaa
    11581 aagagctggt tgctatttac gattatgagg tccctgtacc tgaagatccg ttttccttca
    11641 gacttgagat ccataaatgc tctgaattat ttacaggttc cgtctatcga ctggagcgat
    11701 tccggctacg tccaacattt catcaacgtg atcgagaaga tgctgacccg ctaataaatg
    11761 atgcgttgat ttatataaga gatgagtgta ttgatgagcg gaaattacga ggtgaatcac
    11821 ctgaaactgt aatagcaatt tttaatc
//
LOCUS       DAPGUL010000136        11570 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.139, whole genome shotgun sequence.
ACCESSION   DAPGUL010000136 DAPGUL010000000
VERSION     DAPGUL010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11570
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.139"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            149..847
                     /locus_tag="RHX21_003977"
     CDS             149..847
                     /locus_tag="RHX21_003977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDV1989096.1"
                     /translation="MIFQKIARLLKSEINGNSWHVGDLLPSEAELAVRYNVSRNTLRK
                     ALSLLEGEGIIHRKHGSGTYIQKKNFVAHIDHMNSFSEIAHKSGKEAGSQIMKFEVQD
                     ASPTIATELNLVTGEQVYYIKRLRFIEDNAAQLEETWMSVARFPDLTVSHMQKSKFSY
                     IENECGIKIIGTFETFSPTFPTPEIASILRISPRDPILKIQTQAVDSNSIPLDYSLLY
                     SNIFEFQVKYFFPR"
     gene            complement(892..1791)
                     /gene="eamA"
                     /locus_tag="RHX21_003978"
     CDS             complement(892..1791)
                     /gene="eamA"
                     /locus_tag="RHX21_003978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylserine/cysteine exporter"
                     /protein_id="HDV1989097.1"
                     /translation="MSRKDGVLALLVVVVWGLNFVVIKVGLHNMPPLMLAGLRFMLVA
                     FPAIFFVARPKVPLNLLLGYGLTISFAQFAFLFCAINFGMPAGLASLVLQAQAFFTIV
                     LGAFTFGERLHGKQLAGIALAIFGVLVLIEDSLNGQHVAMLGFMLTLAAAFSWACGNI
                     FNKKIMSHSTRPAVMSLVIWSALIPIIPFFVASLILDGSASMIHSLVTIDMTTILSLM
                     YLAFVATIVGYGIWGTLLGRYETWRVAPLSLLVPVVGLASAALLLDERLTGLQFLGAV
                     LIMTGLYINVFGLRWRKAVKVRG"
     gene            1986..3173
                     /gene="ydeE"
                     /locus_tag="RHX21_003979"
     CDS             1986..3173
                     /gene="ydeE"
                     /locus_tag="RHX21_003979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux MFS transporter YdeE"
                     /protein_id="HDV1989098.1"
                     /translation="MNLSLRRSTSALLASSLLLTIGRGATLPFMTIYLSRQYSLSVDL
                     IGYAMTIALTISVVFSLGFGILADKFDKKRYMLLAITAFASGFIAIPLVNNVKLVVLF
                     FALINCAYSVFATVLKAWFADNLSSTSKTKIFSINYTMLNIGWTIGPPLGTLLVMQSI
                     NLPFWLAAICSAFPMLFIQIWVKRSEKIIATETGSVWSPKVLLQDKALLWFTCSGFLA
                     SFVSGAFASCISQYVMVIADGDFAEKVVAVVLPVNAAMVVTLQYSVGRRLNPANIRAL
                     MTAGTLCFVIGLVGFIFSGNSLLLWGMSAAVFTVGEIIYAPGEYMLIDHIAPPGMKAS
                     YFSAQSLGWLGAAINPLVSGVVLTSLPPSSLFVILALVIIAAWVLMLKGIRARPWGQP
                     ALC"
     gene            3300..3395
                     /gene="mgtS"
                     /locus_tag="RHX21_003980"
     CDS             3300..3395
                     /gene="mgtS"
                     /locus_tag="RHX21_003980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein MgtS"
                     /protein_id="HDV1989099.1"
                     /translation="MLGNMNVFMAVLGIILFSGFLAAYFSHKWDD"
     gene            complement(3614..4504)
                     /gene="dgcZ"
                     /locus_tag="RHX21_003981"
     CDS             complement(3614..4504)
                     /gene="dgcZ"
                     /locus_tag="RHX21_003981"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcZ"
                     /protein_id="HDV1989100.1"
                     /translation="MIKKTTEIDAILLNLNKAIDAHYQWLVSMFHSVVARDASKPEIT
                     DNHSYGLCQFGRWIDHLGPLDNDELPYVRLMDSAHQHMHNCGRELMLAIVENHWQDAH
                     FDAFQEGLLSFTAALTDYKIYLLTIRSNMDVLTGLPGRRVLDESFDHQLRNAEPLNLY
                     LMLLDIDRFKLINDTYGHLIGDVVLRTLATYLASWTRDYETVYRYGGEEFIIIVKAAN
                     DEEACRAGVRICQLVDNHAITHSEGHINITVTAGVSRAFPEEPLDVVIGRADRAMYEG
                     KQTGRNRCMFIDEQNVINRV"
     gene            complement(4759..5151)
                     /gene="ydeI"
                     /locus_tag="RHX21_003982"
     CDS             complement(4759..5151)
                     /gene="ydeI"
                     /locus_tag="RHX21_003982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdeI family stress tolerance OB fold protein"
                     /protein_id="HDV1989101.1"
                     /translation="MKFQAIVLASFLVMPYALADDQGGLKQDAAPPPPHAIEDGYRGT
                     DDAKKMTVDFANTMHDGASVSLRGNLISHKGEDRYVFRDKSGEINVVIPAAVFDGREV
                     QPDQMINISGSLDKKSAPAVVRVTHLQK"
     gene            5427..5945
                     /locus_tag="RHX21_003983"
     CDS             5427..5945
                     /locus_tag="RHX21_003983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxo-tetronate isomerase"
                     /protein_id="HDV1989102.1"
                     /translation="MNINSDKIVQLADTDTIENLTSALSQRLIADQLRLTTAESCTGG
                     KLASALCAAEDTPKFYGAGFVTFTDQAKMKILSVSQQSLERYSAVSEKVAAEMATGAI
                     ERADADVSIAITGYGGPEGGEDGTPAGTVWFAWHIKGQTYTAVMHFAGDCETVLALAV
                     RFALAQLLQLLL"
     gene            complement(5990..8035)
                     /gene="dcp"
                     /locus_tag="RHX21_003984"
     CDS             complement(5990..8035)
                     /gene="dcp"
                     /locus_tag="RHX21_003984"
                     /EC_number="3.4.15.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-dipeptidase Dcp"
                     /protein_id="HDV1989103.1"
                     /translation="MTTMNPFLVQSTLPYLAPHFDQIANHHYRPAFDEGMQQKRAEIA
                     AIALNPQTPDFNNTILALEQSGELLTRVTSVFFAMTAAHTNDELQRLDEQFSAELAEL
                     ANDIYLNGELFARVDAVWQRRESLGLDSESIRLVEVIHQRFVLAGAKLAQADKAKLKV
                     LNTEAATLTSQFNQRLLAANKSGGLVVNDIAQLAGMSEQEIALAAEAAREKGLDNKWL
                     IPLLNTTQQPALAEMRDRATREKLFIAGWTRAEKNDGNDTRAIIQRLVEIRAQQATLL
                     GFPHYAAWKIADQMAKTPEAALNFMREIVPAARQRASDELASIQAVIDKQQGGFSAQP
                     WDWAFYAEQVRREKFDLDEAQLKPYFELNTVLNEGVFWTANQLFGIKFVERFDIPVYH
                     PDVRVWEIFDHNGVGLALFYGDFFARDSKSGGAWMGNFVEQSTLNETHPVIYNVCNYQ
                     KPAAGEPALLLWDDVITLFHEFGHTLHGLFARQRYATLSGTNTPRDFVEFPSQINEHW
                     ATHPQVFARYARHYQSGAAMPDELQQKMRNASLFNKGYEMSELLSAALLDMRWHCLEE
                     NEAMQDVDDFELRALVAENMDLPAIPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADD
                     GYQWFVEQGGLTRENGLRFREAILSRGNSEDLERLYRQWRGKAPQIMPMLQHRGLNI"
     gene            8172..8918
                     /gene="ydfG"
                     /locus_tag="RHX21_003985"
     CDS             8172..8918
                     /gene="ydfG"
                     /locus_tag="RHX21_003985"
                     /EC_number="1.1.1.298"
                     /EC_number="1.1.1.381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional NADP-dependent 3-hydroxy acid
                     dehydrogenase/3-hydroxypropionate dehydrogenase YdfG"
                     /protein_id="HDV1989104.1"
                     /translation="MIVLVTGATAGFGECITRRFIQQGHKVIATGRRQERLQELKDEL
                     GDNLYIAQLDVRNRAAIEEMLASLPAEWSNIDILVNNAGLALGMEPAHKASVEDWETM
                     IDTNNKGLVYMTRAVLPGMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLN
                     LRTDLHGTAVRVTDIEPGLVGGTEFSNVRFKGDDGKAEKTYQNTVALTPEDVSEAVWW
                     VSTLPAHVNINTLEMMPVTQSYAGLNVHRQ"
     gene            9007..9693
                     /gene="ydfH"
                     /locus_tag="RHX21_003986"
     CDS             9007..9693
                     /gene="ydfH"
                     /locus_tag="RHX21_003986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YdfH"
                     /protein_id="HDV1989105.1"
                     /translation="MTVETQLNPTQPVNQQIYRILRRDIVHCLIAPGTPLSEKEVSVR
                     FNVSRQPVREAFIKLAENGLIQIRPQRGSYVNKISMAQVRNGSFIRQAIECAVARRAA
                     SMITESQCYQLEQNLHQQRIAIERKQLDDFFELDDNFHQLLTQIADCQLAWDTIENLK
                     ATVDRVRYMSFDHVSPPEMLLRQHLDIFSALQKRDGDAVERAMTQHLQEISESVRQIR
                     QENSDWFSEE"
     gene            9871..10074
                     /gene="ydfZ"
                     /locus_tag="RHX21_003987"
     CDS             9871..10074
                     /gene="ydfZ"
                     /locus_tag="RHX21_003987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium delivery protein YdfZ"
                     /protein_id="HDV1989106.1"
                     /translation="MTTYDRNRNAITTGSRVMVSGTGHTGKILSIDTEGLTAEQIRRG
                     KTVVVEGCEEKLAPLDLIRLGMN"
     gene            complement(10110..11570)
                     /locus_tag="RHX21_003988"
     CDS             complement(10110..11570)
                     /locus_tag="RHX21_003988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HDV1989107.1"
                     /translation="MGNNLLSAKATLPVYDRNNLAPRIIHLGFGAFHRAHQGVYADIL
                     ATEHFSDWGYYEVNLIGGEQQIADLQQQDNLYTVAEMSADAWTARVVGVVKKALHVQM
                     DGLETVLAAMCEPQIAIVSLTITEKGYFHSPATGQLMLDHPMVAADVQNPHQPKTATG
                     VIVEALARRKAAGLPAFTVMSCDNMPENGHVMRDVVTSYAKAVDEKLAQWIEDNVTFP
                     STMVDRIVPAVTEDTLAKIEQLTGVGDPAGVACEPFRQWVIEDNFVAGRPEWEKAGAE
                     LVSDVLPYEEMKLRMLNGSHSFLAYLGYLAGYQHINDCMEDEHYRYAAYGLMLQEQAP
                     TLKVQGVDLQDYANRLIARYSNPALRHRTWQIAMDGSQKLPQRMLDSVRWHLAHDSKF
                     DLLALGVAGWMRYVGGVDEQGNPIEISDPLLPVIQKAVQSSAEGKARVQSLLAIKAIF
                     GDDLPDNSLFTAKVTEAYLSLLAHGAKATVAKYSVK"
BASE COUNT         3079 a         2864 c         2612 g         3015 t
ORIGIN      
        1 cgcagtagct atacgtcctg gtacattgat cacagtaata cagtgataaa gttgttcaac
       61 atcagggtga ttattaaacg actcggccat acgataaacc aatcaggact caactccttg
      121 ttttcaatgg ctcttaaaag gtgcaaaagt gatttttcaa aagattgccc gcttacttaa
      181 atccgaaatc aatggcaatt catggcatgt tggtgatttg ttgccgtcag aagcggaact
      241 cgctgttcgt tataatgttt cgcgtaatac cctgcgtaag gcattatcct tgctggaagg
      301 cgaaggaatt attcacagaa agcatggttc aggaacatac attcaaaaaa agaattttgt
      361 tgcacacatt gatcacatga acagtttcag tgaaattgcg cataaaagcg gcaaagaggc
      421 agggagtcag attatgaaat ttgaagtgca ggatgcttca cccactattg cgactgagct
      481 gaatttagtg actggtgagc aggtttatta cataaagaga ctgcgattca ttgaggataa
      541 tgcagcacaa ttagaagaaa cgtggatgtc agtagcacgt tttcctgatt taaccgtgtc
      601 acatatgcaa aaatccaaat tttcatatat tgagaatgaa tgcgggatca aaatcattgg
      661 cacctttgaa actttctccc ctacttttcc taccccagaa atcgccagta ttttacggat
      721 cagcccacgg gatcccatac ttaaaattca gacccaggct gtggacagta actctattcc
      781 gctggattat tcgttacttt acagcaatat tttcgagttc caggtaaagt actttttccc
      841 gcgataaaag cagacgcaca gagtgctgac atcacattct gtgcgtatgg tttagcctct
      901 aacctttacc gctttacgcc accgcaagcc aaatacattg atatacagcc cggtcataat
      961 gagcaccgca cctaaaaatt gcagacccgt taagcgttca tccaacaata gtgccgcact
     1021 tgccagtccg actacgggca ccagtaacga taacggtgca acccgccagg tttcatagcg
     1081 tcccagtaac gtcccccaga tcccataacc aacaattgtc gccacaaacg ccagatacat
     1141 cagcgacaag atggtggtca tatcaatagt aaccagactg tgaatcatgg atgcggaacc
     1201 atcgagaatc agcgaggcaa caaagaaggg aatgattggg attaaagcgc tccagattac
     1261 cagcgacatc accgccggac gcgttgagtg cgacatgatc tttttattga agatgttgcc
     1321 acacgcccaa ctaaatgctg cagccagggt caacataaag ccgagcatcg ccacatgctg
     1381 accgttcaga ctatcttcga ttaacaccag tacgccaaaa atcgctaagg cgatccccgc
     1441 caattgtttg ccatgcaatc gctccccgaa agtaaacgcg ccaagcacga tagtaaaaaa
     1501 cgcctgtgcc tgtaacacca gcgaagccag tccagcaggc ataccgaagt taatggcaca
     1561 aaaaagaaaa gcaaactgcg caaaactgat ggttaatcca taccccagca gcaaattcag
     1621 tggtactttc ggtcgtgcga caaaaaagat agccggaaaa gcgaccagca taaagcgcaa
     1681 accggccagc atcagcggtg gcatgttatg aagccccact ttgatgacca caaaatttag
     1741 cccccatacg accactacca gtagcgccaa caccccatct tttcgcgaca ttctaccgcc
     1801 tctgaatttc atcttttgta agcaatcaac ttagctgaat ttacttttct ttaacagttg
     1861 attcgttagt cgccggttac gacggcatta atgcgcaaat aagtcgctat acttcggatt
     1921 tttgccatgc tatttcttta catctctaaa acaaaacata acgaaacgca ctgccggaca
     1981 gacaaatgaa cttatcccta cgacgctcta ccagcgccct tcttgcctcg tcgttgttat
     2041 taaccatcgg acgcggcgct acgctgccat ttatgaccat ttacttgagt cgccagtaca
     2101 gcctgagtgt cgatctaatc ggttatgcga tgacaattgc gctcactatt agcgtcgttt
     2161 ttagcctcgg ttttggtatc ctggcggata agttcgacaa gaaacgctat atgttactgg
     2221 caattaccgc cttcgccagc ggttttattg ccattccttt agtgaataac gtaaagctgg
     2281 tggtgctctt ttttgccctc attaactgcg cctattctgt ttttgctacc gtgctgaaag
     2341 cctggtttgc cgacaatctt tcgtccacca gcaaaacgaa aatcttctca atcaactaca
     2401 ccatgctaaa cattggctgg accatcggtc cgccgctcgg cacgctgttg gtgatgcaga
     2461 gcatcaatct gcccttctgg ctggcagcta tctgttccgc gtttcccatg cttttcattc
     2521 aaatttgggt aaagcgcagc gagaaaatca tcgccacgga aacaggcagt gtctggtcgc
     2581 cgaaagtttt attacaagat aaagcactgt tgtggtttac ctgctctggt tttctggctt
     2641 cttttgtaag cggcgcattt gcttcatgca tttcacaata tgtgatggtg attgctgatg
     2701 gggattttgc cgaaaaggtg gtcgcggttg ttcttccggt gaatgctgcc atggtggtta
     2761 cgttgcaata ttccgtgggc cgccgactta acccggctaa catccgcgcg ctgatgacag
     2821 caggcaccct atgtttcgtc atcggtctgg tcggttttat tttttccggc aacagcctgc
     2881 tattgtgggg tatgtcagct gcggtattta ctgtcggtga aatcatttat gcgccgggcg
     2941 agtatatgtt gattgaccat attgcgccgc caggaatgaa agccagctat ttttccgccc
     3001 agtctttagg ctggcttggt gccgcgatta acccattagt gagtggcgta gtgctaacca
     3061 gcctgccgcc ttcctcgctg tttgtcatct tagcgttggt gatcattgct gcgtgggtgc
     3121 tgatgttaaa agggattcgt gcaagaccgt gggggcagcc cgcgctttgt tgatttaagt
     3181 cgaacacaat aaaaatttaa ttcagccttc gtttaggtta cctctgctaa tatctttctc
     3241 attgagatga aaattaaggt aagcgaggaa acacaccaca ccataaacgg aggcaaataa
     3301 tgctgggtaa tatgaatgtt tttatggccg tactgggaat aattttattt tctggttttc
     3361 tggccgcgta tttcagccac aaatgggatg actaatgaac ggagataatc cctcacctaa
     3421 ccggcccctt gttacagttg tgtacaaggg gcctgatttt tatgacggcg aaaaaaaacc
     3481 gccagtaaac cggcggtgaa tgcttgcatg gatagatttg tgttttgctt ttacgctaac
     3541 aggcattttc ctgcactgat aacggatcgt tgacacagta gcatcagttt tctcaatgaa
     3601 tgttaaacgg agcttaaact cggttaatca cattttgttc atcaataaac atgcagcgat
     3661 ttcttccggt ttgcttaccc tcatacattg cccggtctgc tcttccaatg accacatcca
     3721 gaggctcttc aggaaatgcg cgactgacac ctgctgtcac ggtaatgttg atatgccctt
     3781 cagaatgcgt gatggcatgg ttatcgacta actggcaaat tctgacacct gcacgacatg
     3841 cttcttcatc attagccgct ttgacaataa tgataaattc ttcgcccccg tagcgataaa
     3901 ccgtttcgta atcacgcgtc caactggcta agtaagttgc cagggtgcgt aatactacat
     3961 cgccgattaa atgcccgtag gtatcattaa tcaatttaaa tcggtcaata tccaacaaca
     4021 ttaaataaag attcagaggc tcagcgttgc gtaactgatg atcaaaggat tcatcaagaa
     4081 cccgacgccc cggcaatccc gtcaaaacat ccatattgct acggatcgtc agcaaataaa
     4141 ttttgtaatc ggttaatgcc gcagtaaaag aaagcaaccc ctcctgaaag gcgtcgaaat
     4201 gcgcgtcctg ccagtgattt tcaacaatag ccagcattaa ttcccgacca cagttatgca
     4261 tatgttgatg ggcagaatcc attagccgaa cgtaaggtaa ttcatcgtta tcgagtggcc
     4321 ccagatgatc aatccaccga ccaaactggc acagtccata agaatggtta tccgttattt
     4381 ctggcttact ggcatctctc gcgaccacgc tgtgaaacat actcaccagc cactggtagt
     4441 gggcatcgat agccttattg agatttaaca agatggcatc aatttccgtt gttttcttga
     4501 tcattgccac tcctttttca cagttccttg tgcgcgctat tctaacgaga gaaaagcaaa
     4561 attacgtcaa tattttcata gaaatccgaa gttatgagtc atctctgaga taacattgtg
     4621 atttaaaaca aaatcagcgg ataaaaaagt gtttaattct gtaaattacc tctgcattat
     4681 cgtaaataaa aggatgacaa atagcataac ccaataccct aatggcccag tagttcaggc
     4741 catcaggcta atttattttt atttctgcaa atgagtgacc cgaacgacgg ccggcgcgct
     4801 tttcttatcc agactgccgc taatgttgat catctggtcc ggctgaactt ctcgtccatc
     4861 aaagacggcc gcaggaataa cgacattaat ttcaccgctc ttatcgcgaa aaacgtaacg
     4921 gtcctctcct ttgtgagaaa tcaaattacc gcgtagtgaa accgaagcgc catcgtgcat
     4981 ggtatttgcg aaatcaacgg tcattttttt tgcatcatcg gttccgcgat agccatcttc
     5041 tattgcatga ggcggcggtg gcgctgcatc ctgttttaaa ccgccctggt catctgccaa
     5101 cgcataaggc atgacaagaa aacttgctaa tacaatggcc tgaaatttca tactgactcc
     5161 ttaattgcgt ttggtttgac ttattaagtc tggttgctat ttttataatt gccaaataag
     5221 aatactgcca attgttataa ggcatttaaa atcaggcaac tagctgtcaa atattcagag
     5281 aatttaactc actaaagtta agaagatcaa atagtcttaa atatattttc agaataatcg
     5341 gatttatatg tttgaaaatt attatattgg acgagcatac agaaaaagca aatcaccttt
     5401 acatataaaa gcgtggacaa aaaacagtga acattaatag cgataaaatt gtacaacttg
     5461 cagataccga cactattgaa aacctgacat ccgcgttgag tcaaagactt atcgcggatc
     5521 aattacgctt aactaccgcc gaatcatgca ccggcggtaa gttggctagc gccctgtgtg
     5581 cagctgaaga tacacccaaa ttttacggtg caggctttgt tactttcacc gatcaggcaa
     5641 agatgaaaat cctcagcgta agccagcaat ctcttgaacg atattctgcg gtgagtgaga
     5701 aagtggcagc agaaatggca accggtgcca tagagcgtgc ggatgctgat gtcagtattg
     5761 ccattaccgg ctacggcgga ccggagggcg gtgaagatgg tacgccagcg ggtaccgtct
     5821 ggttcgcgtg gcatattaaa ggccagacct atactgcggt tatgcatttt gctggcgact
     5881 gcgaaacggt attagcttta gcggtgaggt ttgccctcgc ccagctgctg caattactgc
     5941 tataaccagg ctggcctggc gatatctcca ggacagccat tggtggtgtt tatatgttca
     6001 agccacgatg ttgcagcatc ggcataatct gaggagcctt accgcgccat tgtcgataca
     6061 ggcgttccag atcttcgctg ttacctctgg aaaggatcgc ctcgcgaaaa cgcagcccat
     6121 tttcacgcgt taatccgccc tgctcaacaa accactgata accatcatcg gccaacattt
     6181 gtgtccacag ataagcgtaa taacctgcgg catatccgcc accaaaaata tgggcgaaat
     6241 aactgctgcg atagcgtggc ggtatagcag gaagatccat attttccgcc accagcgccc
     6301 gcaattcaaa atcatcgaca tcctgcattg cttcgttttc ttccaggcaa tgccagcgca
     6361 tatcgagaag tgcggcgcta agcagttcgc tcatctcata ccctttgttg aacaggctgg
     6421 cattacgcat tttctgttgc agttcgtcag gcattgctgc cccgctctga taatgccggg
     6481 cgtagcgagc gaatacctgc ggatgcgttg cccagtgttc gttgatttgc gacggaaatt
     6541 cgacaaaatc acgcggcgtg ttggtgccgg aaagcgtggc ataacgctgg cgggcaaaaa
     6601 ggccgtgcag cgtatgacca aattcatgga ataaggttat gacatcatcc cagagtaaca
     6661 acgcaggctc accggcagcg ggtttctgat aattgcaaac gttataaatt accggatgcg
     6721 tttcattaag cgttgattgc tcaacaaaat tgcccatcca tgcaccgccg ctttttgaat
     6781 cacgggcgaa gaaatcaccg taaaataacg ccagtcccac gccattatga tcaaaaattt
     6841 cccacacacg aacgtcagga tggtagacag gaatatcaaa acgttcgaca aacttaatac
     6901 cgaagagctg attcgcggtc cagaatacac cttcattcaa caccgtgttt aattcaaaat
     6961 atggcttgag ctgcgcctca tcaagatcaa atttctcccg ccgtacctgt tcggcataaa
     7021 atgcccagtc ccacggctgc gcgctaaacc cgccctgctg cttatcaata accgcctgta
     7081 tggaggctaa ttcatcgctc gcacgttgac gcgccgctgg aacaatttcc cgcataaagt
     7141 tgagcgctgc ttcaggtgtt tttgccatct gatcggcgat tttccatgcg gcataatgag
     7201 gaaaaccaag taatgtcgcc tgttgtgcac ggatctccac cagacgttga atgatagcgc
     7261 gggtatcatt gccatcattt ttttccgctc gcgtccagcc cgcaataaac agtttttcac
     7321 gcgtcgcacg atcgcgcatt tcggcaagcg ccggctgttg ggtggtattc agcagcggaa
     7381 tcagccattt gttatccaga cctttctcgc gagccgcctc tgccgccagc gcaatctctt
     7441 gctcactcat tcctgccagc tgcgcgatat cgttcacaac cagaccgccg gatttatttg
     7501 ctgccagtaa ccgctggtta aactgactgg tcagtgtcgc agcttctgta ttcagtactt
     7561 ttaattttgc tttatcagct tgcgcaagtt tggctccggc aaggacaaaa cgttgatgaa
     7621 tcacctccac caggcggatg gattcactat caagccccag ggattcacgg cgctgccaga
     7681 cagcatctac ccgcgcgaat aattcaccgt tcagatagat atcattagcc agttccgcca
     7741 gttcagcgga aaactgttca tcaagacgct gtaattcatc attggtatgc gccgcagtca
     7801 tcgcaaaaaa gacgctggta acgcgggtaa gtaattctcc gctttgttcc agtgccagaa
     7861 tagtattgtt gaaatcaggc gtttgcgggt taagcgcgat ggcagcaatt tctgcccgct
     7921 tttgctgcat tccctcatcg aatgccgggc gatagtgatg attggcaatt tgatcaaaat
     7981 gaggagccag atacggcagt gtgctttgca caaggaaagg attcattgtt gtcattttct
     8041 tctcctgaac gcgaggtgtt ccatagcgta ggcttactga taacggagtg caatcttgca
     8101 atccagtatt acccgctctt aagcatcccg tgctatgtta ttgacacaca aaagcgttga
     8161 ggaacagtga gatgatcgtt ttagtaactg gagcaacggc aggttttggt gaatgcatta
     8221 ctcgtcgttt tattcaacaa gggcataaag ttatcgccac tggccgtcgt caggaacggt
     8281 tgcaggagtt aaaagacgaa ctgggagata atctgtatat cgcccaactg gacgttcgca
     8341 accgcgccgc tattgaagag atgctggcat cgctccctgc cgagtggagc aatattgata
     8401 tcctggtaaa taatgccggc ctggcgttgg gcatggagcc tgcgcataaa gccagcgttg
     8461 aagactggga aacgatgatt gataccaaca ataaaggcct ggtatatatg acgcgcgccg
     8521 tcttaccggg tatggttgaa cgtaatcatg gtcatattat taacattggc tcaacggcag
     8581 gtagctggcc ttatgccggt ggtaacgttt acggtgcgac gaaagcgttt gttcgtcagt
     8641 ttagcctgaa tctgcgtacg gacctgcatg gtacggcggt gcgcgtcacc gacatcgaac
     8701 cgggtctggt gggtggcacc gagttttcca atgtccgctt taaaggcgat gacggtaaag
     8761 cggaaaaaac ctatcaaaat accgttgcat tgacgccaga agatgtcagc gaagccgtct
     8821 ggtgggtgtc aacgctgcct gctcacgtca atatcaatac cctggaaatg atgccggtta
     8881 cccaaagcta tgccggactg aatgtccacc gtcagtaatt tttatacccg gcgtaactgc
     8941 cgggttattg cttgtcacaa aaaagtggta gactcatgca gttaactcac tcacaagcaa
     9001 gaacgaatga ccgtcgaaac gcaacttaat cccacacagc ctgtcaatca gcagatttat
     9061 cgtattcttc gtcgcgacat tgtccattgc ctgattgcac caggcacacc gttgtcggaa
     9121 aaagaagttt ctgttcgttt caatgtgtca cgccagccgg ttcgtgaagc ctttattaaa
     9181 ctggcggaaa acggcctgat tcaaattcgt ccgcagcgtg gcagctacgt caacaaaatt
     9241 tccatggccc aggtgcgaaa cggcagtttt atccgtcagg ccattgagtg cgcggtggcg
     9301 cgtcgggcgg cgagcatgat taccgaaagc cagtgctacc aactggaaca aaatcttcac
     9361 cagcaacgca ttgccattga gcgcaagcaa ctggatgatt tttttgaact tgatgacaac
     9421 ttccatcaac tcctgacgca gattgccgac tgtcaactgg cgtgggatac cattgagaac
     9481 ctgaaagcga ccgttgatcg cgtgcgctat atgagtttcg accatgtttc tccaccagaa
     9541 atgctgttac gccagcatct tgatattttc tctgccctgc aaaaacgtga tggcgatgcg
     9601 gtagaacgtg caatgacgca acatttgcag gaaatcagcg aatccgtgcg ccagatccgc
     9661 caggaaaaca gcgactggtt tagcgaagag taattcattt actctcatcc catccgggat
     9721 gagaggcttt tccccccgcc ttacggctca tgcatgcatc aaaaaagatg tgagcttgat
     9781 caaaaacaaa aaatatttca ctcgacagga gtatttatat tgcgcccgtt acgtgggctt
     9841 cgactgtaaa tcagaaagga gaaaacacct atgacgacct acgatcgtaa ccgtaacgca
     9901 atcaccactg gcagccgtgt tatggttagc ggcaccggtc acactggcaa gatcctgtcg
     9961 attgatactg aaggtctgac cgctgagcaa atccgccgcg gaaaaaccgt agttgttgaa
    10021 ggttgtgaag agaaactggc acctctggac ctgattcgtc tcggcatgaa ctaagtgtgt
    10081 gaatgccgcc gatggcggca ttgctttttt tacttcacgg aatatttcgc cacggtcgct
    10141 ttcgcgccat gcgctaataa agacaagtac gcttccgtca cttttgcagt aaacaagcta
    10201 ttgtctggca aatcatcacc aaagattgcc ttaatcgcca gcaatgactg gacgcgcgct
    10261 ttcccttcgg cactactttg tacagccttc tgaataacag gtaacagtgg gtcactgatt
    10321 tctatcggat ttccctgttc atcaacacca ccgacataac gcatccaacc cgcgacgccc
    10381 agcgccagca gatcgaactt gctgtcatgc gccagatgcc agcgaacaga atccaacatc
    10441 cgctgtggca atttctggct accatccatc gcaatctgcc aggttcgatg acgtaacgcc
    10501 gggttgctat agcgtgcaat taatcggtta gcgtaatctt gcaaatcaac gccctgcact
    10561 ttcagcgtcg gcgcttgttc ctgcaacatc aagccatacg ccgcataacg ataatgttca
    10621 tcttccatgc agtcattaat gtgctgatat ccagcaagat aacccaaata cgccaggaat
    10681 gaatgactgc cgttgagcat gcgcaacttc atctcttcat aaggcagcac atcactaacc
    10741 agttcggctc ccgctttttc ccattctgga cgtccggcaa caaagttatc ttctattacc
    10801 cactggcgga aaggttcaca ggcaacgccc gcaggatcgc ccacaccggt aagttgttcg
    10861 attttcgcca gcgtatcctc tgtcactgcg ggcacaatac ggtccaccat tgttgatggg
    10921 aaagtcacgt tatcttcgat ccattgtgcc agtttttcat caacggcttt cgcgtatgaa
    10981 gtgacaacgt cacgcataac atgaccgttt tctggcatgt tgtcacatga catgacggta
    11041 aatgcgggaa gtcctgccgc tttacggcgg gccagcgcct caacaatcac ccctgttgct
    11101 gttttcggct ggtggggatt ttgcacgtcg gcagcgacca tcgggtgatc gagcattaac
    11161 tgtccggtcg ccggagagtg gaaataccct ttttcggtga ttgtcagaga gacaatcgcg
    11221 atttgcggtt cacacatcgc agccaacacg gtttctaagc catccatctg tacgtgcaag
    11281 gcttttttaa cgacgccaac gacgcgagcc gtccacgcat cggccgacat ttccgcaacg
    11341 gtataaagat tatcttgctg ttgtaaatcg gcaatttgct gttcgccgcc gattaagttg
    11401 acctcataat atccccagtc actgaaatgt tctgtagcaa gaatatcggc atacacgccc
    11461 tgatgcgcac ggtgaaatgc accaaagcct aaatgaataa ttcttggggc caggttatta
    11521 cgatcataaa cagggagtgt cgcttttgct gataacaaat tatttcccat
//
LOCUS       DAPGUL010000137        11143 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.140, whole genome shotgun sequence.
ACCESSION   DAPGUL010000137 DAPGUL010000000
VERSION     DAPGUL010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11143
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.140"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            35..139
                     /locus_tag="RHX21_003989"
     CDS             35..139
                     /locus_tag="RHX21_003989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001312672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2618 domain-containing protein"
                     /protein_id="HDV1989108.1"
                     /translation="MENNNRLMPHIRRTTHIMKFAHRNSFDFHFFNAR"
     gene            450..2648
                     /gene="speF"
                     /locus_tag="RHX21_003990"
     CDS             450..2648
                     /gene="speF"
                     /locus_tag="RHX21_003990"
                     /EC_number="4.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine decarboxylase SpeF"
                     /protein_id="HDV1989109.1"
                     /translation="MSELKIAVSRSCPDCFSTHRACVNIDESNYIDVAAIILSVSDVE
                     RGKLDEIDATGYDIPVFIATENEERVPAEYLPRISGVFEHCESRKEFYGRQLETAASH
                     YETQLRPPFFRALVDYVNQGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGEMLFRSDLC
                     NADVAMGDLLIHEGAPCIAQQHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVL
                     FDRNNHKSNHHGALLQAGATPVYLETARNPYGFIGGIDAHCFEESYLRELITEVAPQR
                     AKEARPFRLAVIQLGTYDGTIYNARQVVDKIGHLCDYILFDSAWVGYEQFIPMMADCS
                     PLLLDLNENDPGILVTQSVHKQQAGFSQTSQIHKKDSHIKGQQRYVPHKRMNNAFMMH
                     ASTSPFYPLFAALDINAKMHEGVSGRNMWMDCVVNGINARKLILDNCQHIRPFVPELV
                     DGKPWQSYETAQIAVDLRFFQFVPGEHWHSFEGYAENQYFVDPCKLLLTTPGIDARNG
                     EYEAFGVPATILANFLRENGVVPEKCDLNSILFLLTPAEDMAKLQQLVALLVRFEKLL
                     ESDAPLAEVLPSIYKQHEERYAGYTLRQLCQEMHDLYARHNVKQLQKEMFRKEHFPRV
                     SMNPQEANYAYLRGEVELVRLPDAEGRIAAEGALPYPPGVLCVVPGEIWGGAVLRYFS
                     ALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPRDAQSTLLKGEKL"
     gene            2645..3964
                     /gene="potE"
                     /locus_tag="RHX21_003991"
     CDS             2645..3964
                     /gene="potE"
                     /locus_tag="RHX21_003991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine-ornithine antiporter"
                     /protein_id="HDV1989110.1"
                     /translation="MSQAKSNKMGVVQLTILTMVNMMGSGIIMLPTKLAEVGTISIIS
                     WLVTAVGSMALAWAFAKCGMFSRKSGGMGGYAEYAFGKSGNFMANYTYGVSLLIANVA
                     IAISAVGYGTELLGASLSPVQIGLATIGVLWICTVANFGGARITGQISSITVWGVIIP
                     VVGLCIIGWFWFSPTLYVDSWNPHHAPFFSAVGSSIAMTLWAFLGLESACANTDVVEN
                     PERNVPIAVLGGTLGAAVIYIVSTNVIAGIVPNMELANSTAPFGLAFAQMFTPEVGKV
                     IMALMVMSCCGSLLGWQFTIAQVFKSSSDEGYFPKIFSRVTKVDAPVQGMLTIVIIQS
                     GLALMTISPSLNSQFNVLVNLAVVTNIIPYILSMAALVIIQKVANVPPSKAKVANFVA
                     FVGAMYSFYALYSSGEEAMLYGSIVTFLGWTLYGLVSPRFELKNKHG"
     gene            complement(4020..5660)
                     /gene="pgm"
                     /locus_tag="RHX21_003992"
     CDS             complement(4020..5660)
                     /gene="pgm"
                     /locus_tag="RHX21_003992"
                     /EC_number="5.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-glucose phosphate-specific
                     phosphoglucomutase"
                     /protein_id="HDV1989111.1"
                     /translation="MAIHNRAGQPAQQSDLINVAQLTAQYYVLKPEAGNAEHAVKFGT
                     SGHRGSAARHSFNEPHILAIAQAIAEERAKNSITGPCYVGKDTHALSEPAFISVLEVL
                     AANGVDVIVQENNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPP
                     NGGPADTNVTKVVEDRANALMADGLKGVKRISLDEAMASGHVKEQDLVQPFVEGLADI
                     VDMAAIQKAGLTLGVDPLGGSGIEYWKRIGEYYNLNLTIVNDQVDQTFRFMHLDKDGA
                     IRMDCSSECAMAGLLALRDKFDLAFANDPDYDRHGIVTPAGLMNPNHYLAVAINYLFQ
                     HRPQWGKDVAVGKTLVSSAMIDRVVNDLGRKLVEVPVGFKWFVDGLFDGSFGFGGEES
                     AGASFLRFDGTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAKRFGAPSYNRLQA
                     AATSAQKAALSKLSPEMVSASTLAGDPITARLTAAPGNGASIGGLKVMTDNGWFAARP
                     SGTEDAYKIYCESFLGEEHRKQIEKEAVEIVSEVLKNA"
     gene            complement(5686..6231)
                     /gene="seqA"
                     /locus_tag="RHX21_003993"
     CDS             complement(5686..6231)
                     /gene="seqA"
                     /locus_tag="RHX21_003993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation negative regulator SeqA"
                     /protein_id="HDV1989112.1"
                     /translation="MKTIEVDDELYSYIASHTKHIGESASDILRRMLKFSAASQPAAP
                     VTKEVRVASPAIVEAKPVKTIKDKVRAMRELLLSDEYAEQKRAVNRFMLLLSTLYSLD
                     AQAFAEATESLHGRTRVYFAADEQTLLKNGNQTKPKHVPGTPYWVITNTNTGRKCSMI
                     EHIMQSMQFPAELIEKVCGTI"
     gene            6416..7180
                     /gene="ybfF"
                     /locus_tag="RHX21_003994"
     CDS             6416..7180
                     /gene="ybfF"
                     /locus_tag="RHX21_003994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HDV1989113.1"
                     /translation="MKLNIRAQTAQNQHNNSPIVLVHGLFGSLDNLGVLARDLVNDHN
                     IIQVDMRNHGLSPREPVMNYPAMAQDLVDTLDALQIDKATFIGHSMGGKAVMALTALA
                     PDRIDKLVAIDIAPVDYHVRRHDEIFAAINAVSESDAQTRQQAAAIMRQHLNEEGVIQ
                     FLLKSFVDGEWRFNVPVLWDQYPHIVGWEKIPAWDHPALFIPGGNSPYVSEQYRDDLL
                     AQFPQARAHVIAGAGHWVHAEKPDAVLRAIRRYLND"
     gene            7320..7613
                     /gene="ybfE"
                     /locus_tag="RHX21_003995"
     CDS             7320..7613
                     /gene="ybfE"
                     /locus_tag="RHX21_003995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415211.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA regulated protein"
                     /protein_id="HDV1989114.1"
                     /translation="MAKEQTDRTTLDLFAHERRPGRPKTNPLSRDEQLRINKRNQLKR
                     DKVRGLKRVELKLNAEAVEALNELAESRNMSRSELIEEMLMQQLAALRSQGIV"
     gene            7753..8283
                     /gene="fldA"
                     /locus_tag="RHX21_003996"
     CDS             7753..8283
                     /gene="fldA"
                     /locus_tag="RHX21_003996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin FldA"
                     /protein_id="HDV1989115.1"
                     /translation="MAITGIFFGSDTGNTENIAKMIQKQLGKDVADVHDIAKSSKEDL
                     EAYDILLLGIPTWYYGEAQCDWDDFFPTLEEIDFNGKLVALFGCGDQEDYAEYFCDAL
                     GTIRDIIEPRGATIVGHWPTAGYHFEASKGLADDDHFVGLAIDEDRQPELTAERVEKW
                     VKQISEELHLDEILNA"
     gene            8493..8579
                     /gene="uof"
                     /locus_tag="RHX21_003997"
     CDS             8493..8579
                     /gene="uof"
                     /locus_tag="RHX21_003997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001491546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fur leader peptide"
                     /protein_id="HDV1989116.1"
                     /translation="MIRIISRANSVTSSNEVNRLVTGQIPHD"
     gene            8572..9018
                     /gene="fur"
                     /locus_tag="RHX21_003998"
     CDS             8572..9018
                     /gene="fur"
                     /locus_tag="RHX21_003998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric iron uptake transcriptional regulator"
                     /protein_id="HDV1989117.1"
                     /translation="MTDNNTALKKAGLKVTLPRLKILEVLQEPDNHHVSAEDLYKRLI
                     DMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEF
                     SDDSIEARQREIAAKHGIRLTNHSLYLYGHCAEGDCREDEHAHEGK"
     gene            complement(9102..9428)
                     /locus_tag="RHX21_003999"
     CDS             complement(9102..9428)
                     /locus_tag="RHX21_003999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989118.1"
                     /translation="MKKLILIAIMASGLVACAQSTAPQEDSRLKEAYSACINTAQGSP
                     EKIEACQSVLNVLKKEKQHQQFADQESVRVLDYQQCLRATQTGNDQAVKADCDKVWQE
                     IRSNNK"
     gene            complement(9478..10884)
                     /gene="chiP"
                     /locus_tag="RHX21_004000"
     CDS             complement(9478..10884)
                     /gene="chiP"
                     /locus_tag="RHX21_004000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitoporin"
                     /protein_id="HDV1989119.1"
                     /translation="MRTFSGKRSTLALAIAGVTAMSGFMAMPEARAEGFIDDSTLTGG
                     IYYWQRERDRKDVTDGDKYKTNLSHSTWNANLDFQSGYAADMFGLDIAAFTAIEMAEN
                     GDSSHPNEIAFSKSNKAYDEDWSGDKSGISLYKAAAKFKYGPVWARAGYIQPTGQTLL
                     APHWSFMPGTYQGAEAGANFDYGDAGALSFSYMWTNEYKAPWHLEMDEFYQNDKTTKV
                     DYLHSLGAKYDFKNNFVLEAAFGQAEGYIDQYFAKASYKFDIAGSPLTTSYQFYGTRD
                     KVDDRSVNDLYDGTAWLQALTFGYRAADVVDLRLEGTWVKADGQQGYFLQRMTPTYAS
                     SNGRLDIWWDNRSDFNANGEKAVFFGAMYDLKNWNLPGFAIGASYVYAWDAKPATWQS
                     NPDAYYDKNRTIEESAYSLDAVYTIQDGRAKGTMFKLHFTEYDNHSDIPSWGGGYGNI
                     FQDERDVKFMVIAPFTIF"
BASE COUNT         2700 a         2756 c         2783 g         2904 t
ORIGIN      
        1 taccttcaac tgacacagca agaggtaaag gtaaatggaa aataataacc gcttaatgcc
       61 tcatataagg cggacaaccc atatcatgaa gtttgcccat cgtaatagtt ttgactttca
      121 tttctttaat gcccgctagt cttctgacta aagggcaccc caacgtacag gtctccctga
      181 ctttaagcat tacaggttaa tacctgtatt cctcggtgct catatactgc taaccctttt
      241 aaactctaaa taattcgagt cgcagcactt gcaacttgag gtatgacgag tatagccagt
      301 taccgggctg gtctgggtta ttgcatctgc aaaaagcaaa ctactgattt atttatcagc
      361 ggtggagctt tgcttttttt ccggcgtgat cgatttctcc tttgagaaat tgaggacctg
      421 ctattacctg aaataaagag atgaacaaaa tgtcagaatt aaaaattgcc gttagccgtt
      481 cttgcccgga ttgtttttcc actcatcgtg catgcgtgaa tatagacgaa agtaattata
      541 ttgacgttgc cgccattatt ttatcagtca gtgatgttga acgtggaaaa ctcgatgaaa
      601 tagacgctac tggctatgac attcctgttt ttattgcaac ggaaaatgaa gaacgtgtac
      661 ccgcagaata tctgccacgt atttctggtg tcttcgaaca ttgcgaatca cgtaaagagt
      721 tttatggacg tcagttagaa accgctgcca gccattatga aacgcaactg cgcccgccct
      781 tcttccgcgc actggtcgat tatgttaatc agggcaatag tgcttttgac tgccctggtc
      841 atcagggggg tgagtttttc cgtcgccatc cggcaggcaa tcagttcgtg gaatactttg
      901 gcgaaatgct cttccgctct gacttgtgta atgctgacgt agcaatgggc gatctgctga
      961 ttcatgaagg tgcgccatgt attgcacaac agcatgcggc taaagtcttt aatgccgata
     1021 aaacctattt cgttttaaac ggtacttcat cttctaataa agtggtctta aacgcattgc
     1081 tgacgccggg cgatctggtg ttgtttgacc gcaataacca taaatctaac caccacggtg
     1141 cgttgctaca ggctggcgcg acaccggttt atctggaaac cgcacgtaac ccgtatggct
     1201 ttatcggtgg cattgatgcg cactgttttg aagaaagtta cctgcgtgag ctgattacag
     1261 aagttgcacc gcagcgggca aaagaggctc gtcctttccg cctcgccgtt attcagctag
     1321 gcacttacga cggtacgatt tataacgccc gtcaggtggt ggataaaatt ggtcatctgt
     1381 gtgactacat cctctttgac tccgcatggg tcggctatga acagtttatt ccgatgatgg
     1441 ctgactgttc gccgctgttg ctggatctta atgagaacga tccgggtatt ctggttacgc
     1501 aatccgtaca taaacagcag gctggttttt ctcaaacttc acaaatccat aaaaaagaca
     1561 gccacatcaa agggcaacag cgttatgtac cgcacaaacg catgaacaac gcctttatga
     1621 tgcacgcctc caccagcccg ttctatccgc tgtttgccgc actggatatc aacgccaaaa
     1681 tgcatgaagg tgtcagcggt cgtaatatgt ggatggattg tgtggtaaat ggcattaatg
     1741 cccgcaaact gatcctcgat aactgtcagc atattcgtcc gttcgtacct gaactggtgg
     1801 atggtaaacc ctggcagtcg tatgaaacag cgcaaattgc ggttgatctg cgcttcttcc
     1861 agtttgtacc aggggaacac tggcattctt ttgaaggcta tgcagagaat caatactttg
     1921 tcgatccttg caaactgttg ctgacaaccc caggtattga tgcacgtaac ggcgaatatg
     1981 aagcgttcgg tgtacccgcg acgattcttg ctaacttcct gcgcgaaaat ggcgtagtgc
     2041 cggaaaaatg cgatcttaac tccatcctct tcctgctgac tccggcagaa gatatggcca
     2101 agcttcagca acttgttgcc ctgctggtac gcttcgaaaa actgcttgag tccgacgcgc
     2161 cattagcaga agtgctgcct tccatctaca aacagcatga agagcgctac gccggttata
     2221 ccctgcgtca gttgtgtcaa gaaatgcatg atttgtatgc ccgtcacaac gtgaaacaac
     2281 tgcaaaaaga gatgttccgt aaggaacact tcccacgcgt aagcatgaat ccgcaagaag
     2341 ccaactacgc ctatttacgc ggtgaagtgg agctggttcg tctgccggat gcagaaggcc
     2401 gtatcgctgc cgaaggtgcg cttccttatc ctccgggtgt gctgtgcgtt gttccgggtg
     2461 aaatctgggg tggtgctgtt ctgcgttact tcagcgctct ggaagaaggg atcaacctgt
     2521 tgccaggttt tgcaccggag cttcagggtg tctatatcga agaacatgat ggtcgtaagc
     2581 aagtttggtg ctatgtcatc aagcctcgtg atgcgcaaag caccctgttg aaaggggaaa
     2641 aattatgagt caggctaaat cgaacaaaat gggcgtcgtt cagttaacca tactgacgat
     2701 ggtcaacatg atgggctccg gtatcatcat gctgccgaca aagcttgccg aagttgggac
     2761 aatttcaatt atctcctggc tggtgacagc cgtaggctca atggcactgg catgggcatt
     2821 cgcaaaatgc ggtatgttca gccgtaaatc aggcggtatg ggcggttatg cggagtatgc
     2881 tttcggtaaa tccggtaact ttatggcgaa ctatacctac ggcgtctcgc tgctgattgc
     2941 taacgtcgcg attgctattt cggcggttgg ttacggcacc gaactgctcg gcgcgagttt
     3001 gtcgccagtg cagattggtc ttgcgaccat cggggtgctg tggatttgta ccgtggctaa
     3061 ctttggtggt gcgcgcatta ccgggcaaat cagtagcatt accgtgtggg gggtcattat
     3121 tccggtggta ggcctgtgca ttatcggctg gttctggttt agcccgacgc tttacgttga
     3181 ttcctggaat ccgcatcatg caccgttctt cagtgcagta ggttcttcca tcgctatgac
     3241 gctgtgggct tttctcggtc tggagtctgc gtgtgcgaat actgatgtag tggaaaaccc
     3301 ggaacgtaat gtgccaatcg cggtactcgg cggtacgtta ggtgcggcgg tgatttatat
     3361 cgtctccacc aacgtgattg cagggattgt gcctaatatg gagctggcaa attcaacggc
     3421 accatttggc ctggccttcg cacagatgtt cacaccagaa gtgggtaaag tcattatggc
     3481 gctgatggtg atgtcctgct gcggttcgct gcttggctgg cagttcacca ttgcccaggt
     3541 gtttaaatct tcatctgatg aaggctactt ccctaaaatt ttctcccgtg taaccaaagt
     3601 ggatgcaccg gtgcagggaa tgttgaccat tgtgattatc cagagcgggt tggcgctgat
     3661 gacgattagc ccgtcgctaa acagtcagtt caacgtgctg gttaacctgg ccgtggtgac
     3721 caatatcatt ccgtatattc tgtcaatggc ggcattagtc attattcaga aggtcgctaa
     3781 tgtgcccccc tcaaaagcga aagttgcaaa ctttgttgct tttgttggcg cgatgtatag
     3841 cttttatgcg ctgtactcat ccggggaaga agccatgctg tacggttcca tcgtgacctt
     3901 ccttggttgg acactgtatg gtctggtatc accacgcttt gaactgaaaa ataaacacgg
     3961 ttaaaaaagc aaagtaaaaa agggcgatct tgcgaccgcc ctttttttat taaatgtgtt
     4021 tacgcgtttt tcagaacttc gctaacaatc tcaaccgctt ctttctcaat ctgcttgcga
     4081 tgttcttcac cgaggaagct ttcgcagtag atcttatatg cgtcttccgt gcctgacgga
     4141 cgcgcggcga accagccgtt gtcagtcatc actttcagac cgccaataga agcaccgttg
     4201 cccggagcag cagtcaggcg cgcggtgatc gggtcacctg ccagggtgct ggcgctcacc
     4261 atttccggag acagcttaga cagcgccgct ttttgtgcgg aagtcgcagc tgcctgcaaa
     4321 cggttgtagc tcggcgcacc aaagcgtttt gccagttcgt tgtagtgttc ctgcgggttc
     4381 ttaccggtga cagcggtgat ttccgccgcc agcagacaca taatgatgcc gtctttgtcg
     4441 gtggaccacg gcgtgccgtc gaaacgcagg aaggaagccc ctgcgctctc ttcgccgcca
     4501 aagccgaagc tgccgtcgaa cagaccatca acaaaccatt tgaaacctac cggtacttct
     4561 accagcttac ggcccaagtc attgaccaca cggtcgatca tcgcagaaga aaccagcgtt
     4621 ttaccgacag caacatcttt gccccactgc ggacgatgct ggaacaggta gttgatcgcc
     4681 accgccaggt agtggttcgg attcatcaaa cctgccggag tgacgatacc gtgacggtca
     4741 taatccgggt cgttagcaaa cgccagatcg aacttatcac gcagtgccag cagacccgcc
     4801 atcgcacact cggaggagca gtccatacgg atcgcaccgt ctttatcgag gtgcataaag
     4861 cggaaggttt gatcgacctg atcgttaacg atggtcaggt tgaggttgta atactcgcca
     4921 atgcgcttcc agtattcgat accggaaccg cccaacggat caacgcccag cgtcaggccc
     4981 gctttctgaa tcgccgccat atcaacgata tcggccagcc cttccacgaa cggctgcacc
     5041 agatcctgct ctttcacatg accggatgcc atcgcttcgt cgagggagat acgcttcacg
     5101 cctttcaggc catcggccat cagtgcgttg gccctgtctt ccaccacttt ggtgacgtta
     5161 gtatcagccg ggccaccatt tggcggattg tacttgatac caccatcttc cggcgggtta
     5221 tgggacggtg taatcacgat accgtctgcc agcgggccac cttttttatt gtgaaccagg
     5281 atggcattgg aaacggcagg cgtcggagtg aagccattgt tttcctgcac aatgacatca
     5341 acgccgttcg ctgccagcac ttccagtacg gaaatgaacg caggctcgga cagggcgtga
     5401 gtatctttac ccacatagca agggccagtg atgctgtttt tcgcacgttc ttcagcaatt
     5461 gcctgagcga tcgccagaat gtgcggctcg ttaaagctgt ggcgcgctgc actgccacgg
     5521 tgaccggaag taccgaattt caccgcgtgc tccgcattcc ctgcttctgg tttcagtaca
     5581 taatattgcg ccgtcagttg ggcgacgtta atcaaatcac tctgttgtgc aggttggcct
     5641 gcacgattgt ggattgccat tgctttgtcc tttgtctgca acgttttaga tagttccgca
     5701 aaccttctca atcaattccg ccgggaattg catcgactgc atgatgtgtt cgatcatgct
     5761 gcatttacgg ccggtgttgg tgttggtgat cacccaatac ggcgtgcctg gcacatgttt
     5821 cggcttggtc tgattaccat ttttcagcag cgtttgttca tctgccgcaa agtaaacgcg
     5881 tgtacgaccg tgcaacgatt ccgttgcttc ggcaaacgcc tgggcgtcaa gagaatatag
     5941 tgtagacaac agcagcataa agcgattgac cgctcgcttt tgctctgcgt attcgtccga
     6001 aagcagaagt tcacgcattg cgcgaacctt gtctttaatc gttttgaccg gcttcgcttc
     6061 gacgatagca ggtgacgcaa cgcgaacctc tttcgtcacc ggagcagcag gctgtgatgc
     6121 ggcggaaaat ttcaacatac gccgtaaaat gtcggatgcg ctctcgccga tatgcttagt
     6181 gtggctggca atatagctgt agagttcatc atcaacttca atcgttttca tcttaatcca
     6241 gtgcagtgtc ttagctgaat acaagtcgcc aggagtatat gaataaatcc cggcagcgga
     6301 tagcgtcaag cctggcttgc agaaaaactc ggaataaacc ttatttgttg cagccctgtg
     6361 gcacaatggt caacataata ccctaacccg acaacgcgaa aaaaagaact ttgccatgaa
     6421 attgaatatc cgcgcgcaaa ctgcacaaaa ccagcacaat aattctccca tcgttcttgt
     6481 ccatggtctg tttggtagcc tcgacaacct tggcgtactg gctcgcgatc tggtaaacga
     6541 tcacaatatc atccaggttg atatgcgtaa ccacggtctt tcaccgagag agccggtaat
     6601 gaattacccg gcgatggcgc aggatcttgt tgataccctg gatgcactgc agatcgacaa
     6661 agcaacattt atcggtcact ccatgggcgg taaagcggta atggcactta ctgcactggc
     6721 ccccgatcgc atcgataaac tggtggcgat cgatatcgca ccggtcgact atcacgtacg
     6781 ccgtcatgat gagattttcg cagctatcaa cgcggtcagt gaatcggacg cacaaactcg
     6841 ccagcaagca gcagcaataa tgcgccagca tcttaatgaa gaaggggtga ttcagtttct
     6901 gttgaaatct tttgttgacg gggagtggcg ctttaacgtg ccggtattgt gggatcagta
     6961 tccgcatatt gtgggttggg agaaaatccc ggcatgggat caccctgccc tgtttatccc
     7021 tggcggcaat tctccgtatg ttagcgagca gtaccgtgat gatttactgg cacaatttcc
     7081 acaggcacgg gcgcatgtga ttgcaggcgc gggtcactgg gtccatgctg aaaaaccgga
     7141 tgcggtatta cgcgctatcc gtcgctatct caatgattaa cgcaactgat taaaaaccca
     7201 gcgtccgcgt cgctttccgc gcgtgggcgt tggcgtgact catcgcgctg atgtattatg
     7261 gcgcgctatc catccgggca gaggcctggc tgattgtttc ccccgaagtc accaagatca
     7321 tggccaaaga acaaacggac cgtacgacat tagatctgtt cgcgcacgag cgtcgaccgg
     7381 gacgaccgaa aactaatccg ctttcgcgcg atgaacagct gcgtattaat aaacgcaacc
     7441 agctaaaacg cgacaaagta cgtggcctta agcgtgtcga actgaagctg aacgcggaag
     7501 ctgtcgaggc gctgaacgag ctggcggaat cgcgcaatat gagccgtagc gaactgatcg
     7561 aagagatgtt aatgcagcaa ctggcggcgc tgcgtagtca gggcatcgtt taaatttcca
     7621 gtttcatgta gcacagtgtg cagtcctgct cgtttgctga ttccgcaaga ctgcctgttc
     7681 tgctatgatt gcctttatcc gtgggcaatt ttccaccccc atttcaataa gtttcaagag
     7741 gttatttcac tcatggctat cactggcatc tttttcggca gcgacaccgg taataccgaa
     7801 aatatcgcaa aaatgattca aaaacagctt ggtaaagacg ttgccgatgt ccatgacatt
     7861 gcaaaaagca gcaaagaaga tctggaagct tatgacattc tgctgctggg catcccaacc
     7921 tggtattatg gcgaagcgca gtgtgactgg gatgacttct tcccgactct cgaagagatt
     7981 gatttcaatg gcaaactggt tgcgctgttt ggttgtggtg accaggaaga ttacgccgaa
     8041 tatttctgcg atgcattggg caccatccgc gacatcattg aaccgcgcgg tgcaaccatc
     8101 gttggtcact ggccaactgc gggctatcat ttcgaagcat caaaaggtct ggcagatgac
     8161 gaccactttg tcggtctggc tatcgacgaa gaccgtcagc cggaactgac cgctgaacgt
     8221 gtagaaaaat gggttaaaca gatttctgaa gagttgcatc tcgacgaaat tcttaatgcc
     8281 tgatgtgatg cggcgtagac tcatgtctac gccgtattaa tagataatgc caatcaaaat
     8341 aattgctaca aatttgtaac ttttgctgtt gtacctgtac aatgtcccgg tgttcaagtg
     8401 gccttgccgt tgtaaatgta agctgtgcca cgtttttatt aacaatattt gccagggact
     8461 tgtggttttc atttaggcgt ggcaattcta taatgatacg cattatctca agagcaaatt
     8521 ctgtcacttc ttctaatgaa gtgaaccgct tagtaacagg acagattccg catgactgat
     8581 aacaataccg ccctaaagaa agctggcctg aaagtaacgc ttccacgttt aaaaatcctg
     8641 gaagttcttc aggagccgga caaccatcac gtcagtgcgg aagatttata caaacgtctg
     8701 atcgatatgg gtgaagaaat tggtctggct acggtatatc gcgtactgaa ccagtttgac
     8761 gacgctggta tcgtcacccg ccacaatttt gaaggcggta aatccgtatt tgaactgaca
     8821 cagcaacatc accacgatca cctgatttgc ctcgactgcg gcaaggttat cgaatttagt
     8881 gatgattcca tcgaagcgcg tcagcgtgaa attgccgcaa aacatggcat tcgcctgact
     8941 aaccacagtc tctatcttta cggtcactgt gccgaaggcg attgccgcga agatgagcac
     9001 gcgcacgaag gcaaataagc cagcctgaac gagaaaagcc aacctgcggg ttggcttttt
     9061 tatacaaggg aaataagaaa agcgagagtt acagctctca cttatttgtt attactgcgt
     9121 atttcctgcc agaccttatc acaatcggct ttcaccgcct gatcatttcc ggtttgcgtt
     9181 gcacgcagac actgctgata atccagtacg cgtacacttt cctggtcggc aaactgctga
     9241 tgttgtttct ctttcttcag cacgtttaac acgctctggc aggcttcaat tttttctggc
     9301 gaaccttgtg cggtgttgat acaggcgctg tatgcctctt tcagacgact gtcttcctgt
     9361 ggcgcggttg attgcgcaca agctaccagc cccgatgcca ttatggcgat gagaatcagt
     9421 tttttcatag caaattcctc aaacgtgcgg caggcacaaa acctgccgcg tcgggcatca
     9481 gaagatggtg aatggtgcga ttaccataaa tttcacgtca cgctcatcct ggaagatgtt
     9541 accgtaaccg ccgccccagc ttgggatgtc agagtggttg tcgtattcgg tgaagtgcag
     9601 tttgaacatc gtgcctttgg cgcgaccgtc ctgaatggtg tagaccgcat ccaggctgta
     9661 ggcagactct tcaatagtcc ggtttttgtc gtagtacgca tccggattgc tctgccaggt
     9721 cgcaggttta gcatcccatg cgtaaacgta ggaagcgccg atggcgaagc ctggaagatt
     9781 ccagtttttc aggtcataca tcgcaccgaa gaagaccgct ttttcgccgt tggcgttgaa
     9841 gtcggaacgg ttatcccacc agatatccag gcggccgttg gaggaagcgt aggttggagt
     9901 catacgttgc aggaagtatc cctgctgacc gtcagcctta acccaggtgc cttcgaggcg
     9961 caaatccact acgtcagccg cccggtaacc aaaggtcaac gcttgcagcc aggcggtgcc
    10021 gtcataaagg tcgttgacgc tgcgatcgtc aactttatcg cgcgtaccat agaactggta
    10081 gctggtggtt aacgggctac cggcgatatc aaatttgtag ctggctttgg caaaatattg
    10141 atcgatatac ccttccgcct gaccaaatgc cgcttccagt acgaagttat ttttgaagtc
    10201 gtatttcgcc ccaagggagt gcagataatc aactttggtg gttttatcgt tctgataaaa
    10261 ctcatccatt tccagatgcc acggcgcttt gtattcgttg gtccacatgt aggagaaact
    10321 caacgcacca gcatcgccgt aatcaaaatt cgccccggct tccgccccct gataagtacc
    10381 tggcataaag ctccagtgcg gcgctaacag cgtttgacca gttggctgaa tgtaacctgc
    10441 cctcgcccaa accggaccgt atttaaattt ggccgcagct ttatacaggc ttataccgct
    10501 tttgtcgccg gaccagtctt cgtcataggc tttattactt tttgaaaacg cgatttcgtt
    10561 cgggtgggag ctgtcgccgt tttccgccat ttcaatcgcc gtaaacgcag caatatcaag
    10621 gccgaacata tcagcagcat aaccggactg aaaatcgagg ttggcattcc aggtggagtg
    10681 agaaaggttg gttttgtatt tgtcgccgtc ggtaacatct ttacggtcgc gttcacgctg
    10741 ccagtaatat ataccgccgg ttaaggttga atcgtcgatg aatccttcgg cgcgagcctc
    10801 cggcattgcc ataaagcccg acattgctgt aacaccggcg atagccagcg ccagcgtact
    10861 acgtttgcca ctaaacgtac gcatgggtta atcctctttg acgtataaat tgctgcacca
    10921 aaggtgaaca gcgaaaaaat aaaaattaaa aaagtagcgt tgagaaaagt ctcgctgact
    10981 acaggaacag actatttttc gcgacgcgaa ttatcaatct ctttctgtaa ccagaatgta
    11041 agaacatgag caaccgcaca tattttgatg atttttgtta caaggcttaa gtttgcggtt
    11101 gaaaggcttg cagaagaata aaagcgtgaa tttccagcaa gat
//
LOCUS       DAPGUL010000138        11056 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.141, whole genome shotgun sequence.
ACCESSION   DAPGUL010000138 DAPGUL010000000
VERSION     DAPGUL010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11056
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.141"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            115..876
                     /gene="adiY"
                     /locus_tag="RHX21_004001"
     CDS             115..876
                     /gene="adiY"
                     /locus_tag="RHX21_004001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator AdiY"
                     /protein_id="HDV1989120.1"
                     /translation="MRICSDQPCIVLLTEKDVWIRVNGKEPISLKANHMALLNCENNI
                     IDVSSLNNTLVAHISHDIIKDYLRFLNKDLSQIPVWQRSATPILTLPCLTPDVFRVAA
                     QHSMMPAETESEKERTRALLFTVLSRFLDSKKFLSLMMYMLRNCVSDSVYQIIESDIH
                     KDWNLSMVASCLCLSPSLLKKKLKSENTSYSQIITTCRMRYAVNELMMDGKNISQVSQ
                     SCGYNSTSYFISVFKDFYGMTPLHYVSQHRERTVA"
     gene            1013..2350
                     /gene="adiC"
                     /locus_tag="RHX21_004002"
     CDS             1013..2350
                     /gene="adiC"
                     /locus_tag="RHX21_004002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine/agmatine antiporter"
                     /protein_id="HDV1989121.1"
                     /translation="MSSDADAHKVGLIPVTLMVSGNIMGSGVFLLPANLASTGGIAIY
                     GWLVTIIGALGLSMVYAKMSFLDPSPGGSYAYARRCFGPFLGYQTNVLYWLACWIGNI
                     AMVVIGVGYLSYFFPILKDPLVLTITCVVVLWIFVLLNIVGPKMITRVQAVATVLALI
                     PIVGIAVFGWFWFRGETYMAAWNVSGLGTFGAIQSTLNVTLWSFIGVESASVAAGVVK
                     NPKRNVPIATIGGVLIAAVCYVLSTTAIMGMIPNAALRVSASPFGDAARMALGDTAGA
                     IVSFCAAAGCLGSLGGWTLLAGQTAKAAADDGLFPPIFARVNKAGTPVAGLIIVGILM
                     TIFQLSSISPNATKEFGLVSSVSVIFTLVPYLYTCAALLLLGHGHFGKARPAYLAVTT
                     IAFLYCIWAVVGSGAKEVMWSFVTLMVITAMYALNYNRLHKNPYPLDAPISKD"
     gene            2454..4097
                     /gene="eptA"
                     /locus_tag="RHX21_004003"
     CDS             2454..4097
                     /gene="eptA"
                     /locus_tag="RHX21_004003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418538.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase EptA"
                     /protein_id="HDV1989122.1"
                     /translation="MLKRLLKRPSLNLLAWLLLAAFYISICLNIAFFKQVLQALPLDS
                     LHNVLVFLSMPVVAFSVINIVLTLSSFLWLNRPLACLFILVGAAAQYFIMTYGIVIDR
                     SMIANIIDTTPAESYALMTPQMLLTLGFSGVLAALIACWIKIKPATSRLRSVLFRGAN
                     ILVSVLLILLVAALFYKDYASLFRNNKELVKSLSPSNSIVASWSWYSHQRLANLPLVR
                     IGEDAHRNPLMQNEKRKNLTILIVGETSRAENFSLNGYPRETNPRLAKDNVVYFPNTA
                     SCGTATAVSVPCMFSDMPREHYKEELAQHQEGVLDIIQRAGINVLWNDNDGGCKGACD
                     RVPHQNVTALNLPGQCINGECYDEVLFHGLEEYINNLQGDGVIVLHTIGSHGPTYYNR
                     YPPQFRKFTPTCDTNEIQTCSKEQLVNTYDNTLVYVDYIVDKAINLLKEHQDKFTTSL
                     VYLSDHGESLGENGIYLHGLPYAIAPDSQKQVPMLLWLSEDYQKRYQVDQNCLQKQAQ
                     TQHYSQDNLFSTLLGLTGVETKYYQAADDILQTCRRVSE"
     gene            4094..4762
                     /gene="basR"
                     /locus_tag="RHX21_004004"
     CDS             4094..4762
                     /gene="basR"
                     /locus_tag="RHX21_004004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BasR"
                     /protein_id="HDV1989123.1"
                     /translation="MKILIVEDDTLLLQGLILAAQTEGYACDGVTTARMAEQSLEAGH
                     YSLVVLDLGLPDEDGLHFLARIRQKKYTLPVLILTARDTLTDKIAGLDVGADDYLVKP
                     FALEELHARIRALLRRHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSR
                     LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVA
                     NEEN"
     gene            4763..5863
                     /gene="pmrB"
                     /locus_tag="RHX21_004005"
     CDS             4763..5863
                     /gene="pmrB"
                     /locus_tag="RHX21_004005"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PmrB"
                     /protein_id="HDV1989124.1"
                     /translation="MNLMHFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQI
                     QLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLTLFICYQAVRRITRPLAELQ
                     KELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTP
                     LAGVRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLE
                     DVILPSYDELSTMLDQRQQTLLLPESAADITVQGDATLLRMLLRNLVENAHRYSPQGS
                     NIMIKLQEDGGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGLGLSIVSRITQL
                     HHGQFFLQNRQETSGTRAWVRLKKDQNVANQI"
     gene            complement(5839..5928)
                     /gene="pmrR"
                     /locus_tag="RHX21_004006"
     CDS             complement(5839..5928)
                     /gene="pmrR"
                     /locus_tag="RHX21_004006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LpxT activity modulator PmrR"
                     /protein_id="HDV1989125.1"
                     /translation="MKNRVYESLTTVFSVLVVSSFLYIWFATF"
     gene            complement(6040..7542)
                     /gene="proP"
                     /locus_tag="RHX21_004007"
     CDS             complement(6040..7542)
                     /gene="proP"
                     /locus_tag="RHX21_004007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709830.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline transporter ProP"
                     /protein_id="HDV1989126.1"
                     /translation="MLKRKKVKPITLRDVTIIDDGKLRKAITAASLGNAMEWFDFGVY
                     GFVAYALGKVFFPGADPSVQMVAALATFSVPFLIRPLGGLFFGMLGDKYGRQKILAIT
                     IVIMSISTFCIGLIPSYDTIGIWAPILLLICKMAQGFSVGGEYTGASIFVAEYSPDRK
                     RGFMGSWLDFGSIAGFVLGAGVVVLISTIVGEANFLDWGWRIPFFIALPLGIIGLYLR
                     HALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKHWRSLLTCIGLVIATNVTYY
                     MLLTYMPSYLSHNLHYSEDHGVLIIIAIMIGMLFVQPVMGLLSDRFGRRPFVLLGSVA
                     LFVLAIPAFILINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTHIRYSALAAA
                     FNISVLVAGLTPTLAAWLVESSQNLMMPAYYLMVVAVIGLITGVTMKETANRPLKGAT
                     PAASDIQEAKEILVEHYDNIEQKIDNIDHEIADLQAKRTRLVQQHPRIDE"
     gene            complement(7806..8684)
                     /locus_tag="RHX21_004008"
     CDS             complement(7806..8684)
                     /locus_tag="RHX21_004008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418534.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjcZ-like family protein"
                     /protein_id="HDV1989127.1"
                     /translation="MTKTLLDGPGRVLESVYPRFLVDLAQGDDARLPQAHQQQFRERL
                     MQELLARVQLQTWTNGGMLNAPLSLRLTMVEKLASMLDPGHLALTQIAQHLALLQKMD
                     HRQHSAFPELPQQIAALYEWFSARCRWKEKALTQRGLLVQAGDQSEQIFTRWRAGAYN
                     AWSLPGRCFIVLEELRWGAFGDACRLGSPQAVALLLGDLRVKATQHLAESINAAPTTR
                     HYYHQWFASSTVPTGGDHADFLSWLGKWTTADKQPVCWSVTQRWQTVALGMPRLCSAQ
                     RLAGAMVEEIFSVNLA"
     gene            complement(8681..10909)
                     /gene="crfC"
                     /locus_tag="RHX21_004009"
     CDS             complement(8681..10909)
                     /gene="crfC"
                     /locus_tag="RHX21_004009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="clamp-binding protein CrfC"
                     /protein_id="HDV1989128.1"
                     /translation="MYTQTLYELSQEAERLLQLSRQQLQLLEKMPLSVPGDDAPQLAL
                     PWSQPNIAERHAMLNNELRKISRLEMVLAIVGTMKAGKSTTINAIVGTEVLPNRNRPM
                     TALPTLIRHTPGQKEPVLHFSHVAPIDCLIQQLQQRLRDCDIKHLTDVLEIDKDMRAL
                     MQRIENGVAFEKYYLGAQPIFHCLKSLNDLVRLAKALDVDFPFSAYAAIEHIPVIEVE
                     FVHLAGLESYPGQLTLLDTPGPNEAGQPHLQKMLNQQLARASAVLAVLDYTQLKSISD
                     EEVREAILAVGQSVPLYVLVNKFDQQDRNSDDADQVRALISGTLMKGCITPQQIFPVS
                     SMWGYLANRARHELANNGKLPAPEQQRWVEDFAHAALGRRWRHDDLADLEHIRHAADQ
                     LWEDSLFAQPIQALLHAAYANASLYALRSAAHKLLNYAQQARGYLDFRAHGLNVACEQ
                     LRQNIHQVEESLQLLQLNQAQVSGEVKHEIELALTSANHFLRQQQDALNAQLAALFQD
                     DSEPLSEIRTCCETLLQTAQNTISRDFTLRFAELESTLCRVLTDVIRPIEQQVKMELS
                     ESGFRPGFHFPVFHGVVPHFNTRQLFSEVISRQDATDEQSTRLGVVRETFSRWLNQPD
                     WGRGNEKSPTETVDYSVLQRALSAEVDLYCQQMAKVLAEQVDESVTAGMNTFFAEFAS
                     CLTELQTRLRESLALRQQNESVVRLMQQQLQQTVMTHGWIYTDAQLLRDDIQTLFTAE
                     RY"
BASE COUNT         2773 a         2870 c         2707 g         2706 t
ORIGIN      
        1 aaaactcgtt atttttatgc atgtttatat tcatcataca attatataac catttcccgg
       61 tatcgctttg ctttagcgag aactggtctt ttatttgcac tcaggagtac atgtatgagg
      121 atttgcagcg accaaccttg tattgtttta ttgactgaaa aagatgtctg gataagggtg
      181 aatgggaaag aacctattag ccttaaagct aaccatatgg cgttattaaa ttgtgaaaat
      241 aatattatcg acgtctcctc tcttaacaac actttggttg ctcatattag tcacgacatc
      301 atcaaagatt acctccggtt tctgaataaa gatctctcgc aaataccagt atggcaacgt
      361 agcgctacgc ccatactcac cctgccatgc ctgacgccag acgtctttcg cgttgccgcg
      421 caacacagca tgatgcccgc agaaactgag tcagaaaagg aacgaacacg cgcattatta
      481 ttcacggtgc tatcccgttt tctcgacagt aaaaaattcc tttcattaat gatgtatatg
      541 ttacgtaatt gtgtaagtga cagcgtttat caaattattg aaagcgatat tcacaaagac
      601 tggaatctta gtatggtagc cagttgttta tgtcttagcc caagtctgtt aaagaaaaag
      661 ttgaaaagcg aaaacaccag ttatagccaa ataatcacca cctgccgcat gcgttatgcc
      721 gtaaatgaat taatgatgga cggtaaaaat atctctcagg tatcacagtc ctgcggctac
      781 aacagtacgt cgtactttat ttctgtcttt aaagacttct acggtatgac gccgctgcat
      841 tatgttagtc agcacagaga acgcactgtc gcctgatttt taaccttaac gaagagctat
      901 attaataacg gcatcagcga taacccggtc gataataatt caactatcga atgcaggcgt
      961 atgatatgac gtaatttatt gtcacgaagc tcgccttcgc aggagtttaa ttatgtcttc
     1021 ggatgctgat gctcacaaag tgggcttaat ccccgtcacc ctgatggtgt cggggaatat
     1081 tatggggtca ggtgtttttc tgttacctgc aaacctggcc tctactggcg ggattgccat
     1141 ttatggatgg ttggtgacga ttatcggtgc actggggctc tcgatggtat acgccaaaat
     1201 gtcgttcctc gacccaagtc ctggtggttc ttacgcttac gcccgccgct gctttggccc
     1261 gtttctcggt tatcaaacca acgtcctcta ctggctggcc tgctggatcg gcaatatcgc
     1321 catggtggtc attggcgtag gatatttaag ttacttcttc ccgattctga aagatccatt
     1381 ggtattaacc atcacctgcg tcgtggtgct gtggatcttc gtcctgctga acattgtcgg
     1441 tccgaaaatg atcacccgtg tgcaggcagt tgccaccgtg ctggcgctga tccccatcgt
     1501 cgggattgcc gtatttggct ggttctggtt ccgtggtgaa acctatatgg cggcatggaa
     1561 cgtcagcggc ctgggcacct tcggtgcaat tcaaagtacc cttaacgtta cgctgtggtc
     1621 gttcatcggt gtggaaagtg cctccgttgc cgcaggtgtg gtgaaaaacc cgaaacgcaa
     1681 tgtccctatc gccaccattg gtggggtatt gattgccgcc gtttgctatg tactttctac
     1741 caccgcgatt atggggatga tccctaatgc cgcactgcgc gtttctgctt cgccattcgg
     1801 tgatgccgca cggatggcgt tgggtgacac cgccggggcc attgtttcct tctgcgcagc
     1861 tgcgggttgc ttaggttcac tgggcggctg gacgttgctg gcgggtcaaa cggcgaaagc
     1921 cgctgccgat gacggactgt tcccaccaat ttttgcccgt gtaaataaag cgggtacgcc
     1981 agtggcgggg ctgattatcg tcggtatttt gatgaccatc ttccagctca gcagcatttc
     2041 accaaacgcg accaaagagt tcggtctggt ttcttccgtc tcggtcatct ttacactggt
     2101 gccatatctt tacacctgtg cggcgttact gctgctcgga cacggtcact ttggtaaagc
     2161 acgcccggca tatctggcag ttactaccat tgccttcctc tactgcatct gggccgtggt
     2221 ggggtccgga gcgaaagagg ttatgtggtc atttgtcacc ctgatggtca tcaccgccat
     2281 gtatgcgctg aattacaacc ggctacataa aaacccgtat cccttagatg caccaataag
     2341 caaagattaa ttccccttaa tccagcaaac ataaaagcca accttaagaa cttaaggttg
     2401 gcttaatttt gctttgcgag catatgcgca ctttgttcga tggaaacacc gtgatgttga
     2461 agcgcctact aaaaagaccc tctttgaatt tactcgcctg gctattgttg gccgcttttt
     2521 atatctctat ctgcctgaat attgcctttt ttaaacaggt gttgcaggcg ctgccgctgg
     2581 attcgctgca taacgtactg gttttcttgt cgatgccggt cgtcgctttc agcgtgatta
     2641 atattgtcct gacactaagc tctttcttat ggcttaatcg accactggcc tgcctgttta
     2701 ttctggttgg cgcggctgca caatatttca taatgactta cggcatcgtc atcgaccgct
     2761 cgatgattgc caatattatt gataccactc cggcagaaag ttatgcgctg atgacaccgc
     2821 aaatgttatt aacgctggga ttcagcggcg tgcttgctgc gctgattgcc tgctggataa
     2881 aaatcaaacc tgccacctcg cgtctgcgca gtgttctttt ccgtggagcc aatattctgg
     2941 tttctgtact actgattttg ctggtcgccg cactgtttta taaagactac gcctcgttgt
     3001 tccgcaataa caaagagctg gtgaaatcct taagcccctc taacagcatt gttgccagct
     3061 ggtcatggta ctcccatcag cgactggcaa atctaccgct ggtgcgaatt ggtgaagacg
     3121 cccaccgcaa cccgttaatg cagaacgaaa aacgtaaaaa tttgaccatc ctgattgtcg
     3181 gcgaaacctc gcgggcggag aacttctccc tcaacggcta cccgcgtgaa actaacccgc
     3241 ggctggcgaa agataacgtg gtctatttcc ctaataccgc atcttgcggc acggcaacgg
     3301 cagtttcagt accgtgcatg ttctcggata tgccgcgtga gcattacaaa gaagagctgg
     3361 cacagcacca ggaaggcgtg ctggatatca ttcagcgagc gggcatcaac gtgctgtgga
     3421 atgacaacga tggcggctgt aaaggtgcct gcgaccgcgt gcctcaccag aacgtcaccg
     3481 cgctgaatct gcctggtcag tgcatcaacg gcgaatgcta tgacgaagta ctgttccacg
     3541 ggctggaaga gtacatcaat aacctgcagg gtgatggcgt gattgtctta cacaccatcg
     3601 gcagccacgg tccgacctat tacaaccgct atccgccgca gttcaggaaa tttaccccaa
     3661 cctgcgacac caatgagatc cagacctgta gcaaagagca actggtgaac acttacgaca
     3721 acacgctggt ttacgtcgac tatattgttg ataaagcgat taatctgctg aaagaacatc
     3781 aggataaatt taccaccagc ctggtttatc tttctgacca cggtgaatcg ttaggtgaaa
     3841 atggcatcta tctgcacggt ctgccttatg ccatcgcccc ggatagccaa aaacaggtgc
     3901 cgatgctgct gtggctgtcg gaggattatc aaaaacggta tcaggttgac cagaactgcc
     3961 tgcaaaaaca ggcgcaaacg caacactatt cacaagacaa tttattctcc acgctattgg
     4021 gattaactgg cgttgagacg aagtattacc aggctgcgga tgatattctg caaacttgca
     4081 ggagagtgag tgaatgaaaa ttctgattgt tgaagacgat acgctgttat tgcagggatt
     4141 gattctggcg gcgcaaactg aaggctacgc gtgcgatggc gtgacaaccg cgcggatggc
     4201 ggaacaaagc cttgaggccg gtcattacag cctggtggta ctggatttag ggttacccga
     4261 cgaagatgga ctgcattttc tcgcccgtat ccggcagaaa aaatataccc tgccggtact
     4321 gatcctcacc gctcgcgata cgctgaccga caaaatcgcc gggctggatg tcggtgccga
     4381 tgactatctg gtgaagcctt ttgcgctgga agagttacac gcccgtatcc gcgccctgct
     4441 acgacgccat aataatcagg gcgaaagtga gctgattgtt ggcaatctga cgctgaatat
     4501 gggtcgccgt caggtatgga tgggcggtga agagttgatt ctgacgccca aagaatatgc
     4561 tctgctgtca cggttaatgc tcaaagcagg cagtccggtg catcgggaaa ttctctacaa
     4621 cgacatctat aactgggaca atgaaccctc gaccaacacc ctggaagtgc atatccacaa
     4681 tctgcgcgac aaagtgggca aagcccgtat ccgcaccgtg cgcggctttg gctatatgct
     4741 ggtcgcgaat gaggaaaact aattgaatct gatgcatttt ctgcgccgac caatatcgct
     4801 gcgccaacgg ctgatattga ccatcggggc cattttgttg gtgtttgagc tgatcagcgt
     4861 cttctggcta tggcatgaaa gtaccgagca gattcagctg tttgagcagg cgctacgcga
     4921 caatcgcaac aacgatcgcc acatcatgcg tgagatccgc gaggcggtcg ccagcctgat
     4981 tgtccccggc gtctttatgg tcagcctgac gctatttatc tgctatcagg cggtacgccg
     5041 catcacccgc ccgctggcgg agctgcaaaa agagctggaa gcgcgcaccg ccgacaactt
     5101 aacgcccatt gccattcaca gcgccaccct cgaaatcgaa gcggtggttt cggcgttgaa
     5161 cgatctggtc agtcgcctga ccagcacgct ggataacgaa aggttgttta ccgctgacgt
     5221 cgcgcacgaa ctgcgaacgc cactggcggg ggtgcgtttg catctggaac tgctggcgaa
     5281 aacgcatcac attgatgtag caccgttagt ggcacggctt gatcagatga tggagagcgt
     5341 ctcccagctg ctgcaactgg cgcgtgccgg acagtcattt tcttccggta attatcaaca
     5401 tgtaaaactg ctggaagatg tcattctccc ctcgtatgac gaactcagta ccatgctcga
     5461 ccagcgacag caaaccctgc tattgccaga gagcgccgcc gacatcaccg ttcagggtga
     5521 tgcaaccctg ctgcggatgt tattgcgaaa cctggtagaa aacgcccatc gttacagccc
     5581 gcaaggcagc aacattatga ttaagctgca agaagatggc ggagcggtca tggcagttga
     5641 agatgaagga ccaggtattg atgagagtaa atgcggggag ttgagtaaag cgtttgtacg
     5701 tatggacagc cgttatggcg ggattggtct ggggttaagt attgtcagcc gcattacaca
     5761 gttgcatcac gggcagtttt tcctgcaaaa ccggcaagag acttccggca cgcgggcctg
     5821 ggtacggctg aagaaagatc agaacgtggc aaaccagata taaagaaagc tgctgaccac
     5881 cagcacgctg aacacggtag ttaaactttc ataaacacgg tttttcattg cactctcctc
     5941 cgttaacctg gaggagagta tgcgcgtcag agattaagtg aaccttaaga gttcaattgg
     6001 cctgataaga cagcgtcaca tcaggccatc cgtttcagct tattcatcaa ttcgcggatg
     6061 ttgctgcacc aggcgggtac gtttcgcctg caaatcggca atctcgtggt caatattatc
     6121 gattttctgc tcgatattat cgtaatgctc gacgagaatt tccttcgctt cctgtatatc
     6181 tgacgccgcc ggtgtcgcac ctttcaacgg acgatttgcc gtctctttca tggttacgcc
     6241 ggtgattaaa ccaatcaccg ccactaccat caggtaatag gcaggcatca tcagattctg
     6301 cgagctttcg accagccagg ccgccagtgt tggcgtcaga ccggcaacca gcaccgaaat
     6361 attaaatgcc gccgccagcg cgctgtaacg gatatgcgtc gggaacatcg ctggcaaggt
     6421 agaagccata acgcccgtaa agcagttaag gatcaccgcc agcatcagta acccggcaaa
     6481 aatcaggccg atgacgttac tgttaatcag aataaacgcc gggatcgcca acacaaacag
     6541 ggcaacacta ccaagtagca caaacggacg acggccaaaa cggtcactca gcaagcccat
     6601 caccggctgg acaaacagca taccgatcat aatggcgata ataatcagca ccccgtggtc
     6661 ttcggagtaa tgcaggttat gcgacaaata actcggcata taggtcagca acatgtagta
     6721 agtcacgttg gtggcaatta ccagaccaat acatgtcaac aggctgcgcc agtgtttggt
     6781 ggcaatctct ttaaacgaga ctttcgggcc atcctgcaaa ccttcgcggt cgccctgttc
     6841 cagtttatcg acatgctgct ggaacgccgg agtttcttcc agcgcatggc gcaggtaaag
     6901 cccgataatc cctaacggca gagcaataaa gaacggaata cgccagcccc agtcgaggaa
     6961 gttcgcttcg ccgacaatgg tcgaaattaa caccactacg ccagcaccca gcacaaaccc
     7021 ggcaatagaa ccgaagtcca gccagctgcc cataaagcca cgtttacggt caggtgagta
     7081 ttccgcaaca aatatcgacg ccccggtata ttcaccgccg accgagaaac cttgtgccat
     7141 cttacagatc aacagcagaa tcggtgccca aataccaatc gtgtcgtagg acggtattaa
     7201 gccaatacag aacgtactga tcgacataat cacaatagtg atagcgagga tcttctggcg
     7261 accatattta tcgcccaaca taccaaagaa gagcccgcca agcggtcgaa tcagaaaggg
     7321 aacggagaac gtggcaagtg cagcaaccat ctgcacgctg gggtcagccc ccgggaaaaa
     7381 aactttacct aatgcgtaag caacaaaacc ataaacacca aaatcaaacc attccattgc
     7441 attacccagt gatgctgcgg taatggcttt acgcagttta ccgtcatcaa taatggtgac
     7501 atcacgaagg gtaatcggtt ttactttttt ccttttcagc atagctttcc tcgcagagtt
     7561 ggcccatttc cgcaaacgcc agaaaaatca gcgcgacggc cgcaaaaggg gagcgggaat
     7621 tgcaggatgc aatctctgta acaagcgtag cgggtttgct tacaccctcc ggttaaggaa
     7681 tgtacaatca aaccagttga cgcctgaatt gggcagttaa tgaccttttt accctaccag
     7741 tgtttaaatt tgtgatcaac ttcacacatg gatttcgttt aggactcatt gatgtaactg
     7801 attatttacg ccaaatttac agagaagatt tcctcgacca ttgcccccgc cagacgctgc
     7861 gctgaacaga gtcgtggcat ccccagcgcg acagtttgcc agcgttgggt cactgaccag
     7921 caaacgggtt gtttatctgc cgtggtccac tttcccagcc aacttaaaaa atcagcatga
     7981 tccccgcccg tcggaacggt cgaagaggca aaccactgat ggtaatagtg acgcgtggtc
     8041 ggggccgcat tgatactctc tgccagatgt tgtgtcgctt tcacgcgcaa atcacccagc
     8101 aacaacgcca ccgcttgcgg gcttcccaga cgacaggcat cgccaaatgc cccccaacgc
     8161 aactcttcga gaacgataaa acagcgccca ggcaacgacc aggcgttata cgccccagca
     8221 cgccagcggg taaaaatttg ctcgctctga tcacctgcct gcaccagtag gcctcgttgc
     8281 gttaacgcct tttccttcca gcggcaacgg gctgaaaacc actcatacaa ggcggcaatt
     8341 tgctggggga gctccgggaa agcagagtgc tggcggtgat ccattttttg cagcagcgcc
     8401 agatgctgcg cgatctgcgt cagcgccaga tgaccgggat ccagcatcga cgccagtttt
     8461 tccaccattg tcagtcgcag gctaagcggc gcatttaaca tgccgccgtt cgtccatgtc
     8521 tgaagctgca cgcgcgcaag aagttcctgc atcagtcgtt cacgaaactg ctgctgatgg
     8581 gcttgtggaa ggcgggcatc atcgccctgc gccagatcca ctaaaaagcg gggataaacc
     8641 gactccagca cgcgaccggg gccgtcaagt aacgtcttgg tcaatatcgt tctgccgtga
     8701 aaagtgtttg aatatcatcg cgtaacagct gggcgtcggt gtaaatccag ccgtgagtca
     8761 tcacagtctg ctgcaattgc tgctgcatca gcctgaccac cgattcattt tgttgacgca
     8821 gagccagact ttcgcgtaaa cgcgtctgta attccgtcaa acatgaagcg aactcagcga
     8881 aaaaagtatt catgcctgcc gtaacagatt catcgacctg ctctgccaga actttagcca
     8941 tttgttggca ataaagatcg acttctgcgc ttaaagctcg ttgcaacaca ctgtaatcaa
     9001 ccgtttctgt cggggatttc tcatttcccc gtccccagtc gggctgattc aaccagcgcg
     9061 aaaaagtctc acgcacaacg cctaaacgcg tgctctgctc gtccgttgca tcctggcgcg
     9121 aaatgacttc actgaacagc tggcgagtgt tgaagtgggg aactacgccg tgaaaaacag
     9181 gaaaatgaaa cccaggacga aaccctgact cgctcaattc cattttgact tgttgctcaa
     9241 tgggccgaat aacatcggtt aacacccggc aaagggtgga ttcaagctcg gcaaaacgca
     9301 gcgtaaagtc gcgactgatg gtgttctgcg ccgtctgtaa cagtgtctca cagcaggtac
     9361 gaatctcgct taacggctcc gaatcatcct gaaacaaggc ggctaactgc gcattcagcg
     9421 catcttgctg ttgacgcaga aagtggttgg cggaggtcag ggccagctcg atttcatgtt
     9481 taacctcgcc gctcacctgc gcctgattga gttgcaatag ctgcaaactt tcttcgacct
     9541 gatggatatt ttgccgcaat tgttcacaag cgacgtttaa cccgtgcgca cgaaaatcca
     9601 ggtatccccg cgcctgctgc gcgtaattca acagtttatg cgcagcagat cgcagagcat
     9661 acaacgaggc gttagcgtaa gcggcatgaa gcaacgcctg aattggctgg gcgaacagcg
     9721 aatcttccca caactgatcg gcagcatgac gaatatgttc gaggtccgcc agatcgtcat
     9781 gacgccagcg cctgccgagc gcagcatggg caaaatcttc cacccagcgt tgttgctctg
     9841 gcgctggtaa cttaccgttg ttggctaact catggcgcgc tcgattcgcc aggtagcccc
     9901 acatcgacga caccggaaat atctgctgtg gcgtaataca gcctttcatc agcgtcccgg
     9961 aaatcagtgc ccgcacctgg tcggcgtcgt cactgttacg atcctgttga tcgaacttat
    10021 tgaccagcac atacagcggc accgattgcc ccaccgccaa aatcgcctca cggacctctt
    10081 catcggagat cgatttcagt tgcgtataat ccagcaccgc cagtaccgcc gaggcgcgtg
    10141 ccagctgctg gttaagcatt ttttgcagat gcggttgccc ggcttcattt ggcccggggg
    10201 tatccagtaa cgtcaactga ccgggataac tctccagccc cgccagatgg acaaactcca
    10261 cttcaatcac gggaatatgc tcaatggcgg cgtaagcaga aaaaggaaaa tcgacgtcca
    10321 gcgccttcgc cagtcgcact aaatcattca aacttttcag acaatgaaaa ataggctggg
    10381 cacccagata atatttttcg aaagcgacgc cattttcgat ccgctgcata agcgcacgca
    10441 tatctttatc tatttccagc acatcggtca gatgcttaat atcgcaatca cgcaggcgct
    10501 gttgtaattg ttgaattaaa caatcgattg gcgcgacatg tgaaaaatgc agtaccggtt
    10561 ccttttgccc gggcgtatgg cgaataagcg tcggcagcgc agtcattggg cgattacgat
    10621 taggcagaac ctccgtacca acaatggcat taatggtggt tgatttccct gctttcatgg
    10681 taccgacaat tgccagcacc atttccagtc gggaaatttt acgcaactca ttattcagca
    10741 tcgcgtgacg ttcggcgata ttaggctgac tccagggtaa agccagttgt ggcgcgtcgt
    10801 ctccgggtac agagagaggc attttttcca gtaactgcaa ctgttggcga gaaagctgta
    10861 acaggcgttc agcctcctga cttaactcat acagggtctg tgtgtacata gaaaattctt
    10921 ccttaaagca aattttgtta cttttattta gccagattgt ttttgagttc tgttttcggc
    10981 ttttataatt actgcaagaa ataattttat atttagtgtg ttgtttttta tcagaataaa
    11041 taacgtcttc tgatac
//
LOCUS       DAPGUL010000139        10916 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.142, whole genome shotgun sequence.
ACCESSION   DAPGUL010000139 DAPGUL010000000
VERSION     DAPGUL010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10916)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10916)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10916
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.142"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(137..943)
                     /gene="trpA"
                     /locus_tag="RHX21_004010"
     CDS             complement(137..943)
                     /gene="trpA"
                     /locus_tag="RHX21_004010"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HDV1989129.1"
                     /translation="MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLKIIDTLIEAG
                     ADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMY
                     ANLVFNKGIDEFYAQCEKVGVDSVLVADVPIEESAPFRQAALRHNVAPIFICPPNADD
                     DLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVAKLKEYNAAPPLQGFGISAPD
                     QVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKVFVQPMKAATRS"
     gene            complement(943..2136)
                     /gene="trpB"
                     /locus_tag="RHX21_004011"
     CDS             complement(943..2136)
                     /gene="trpB"
                     /locus_tag="RHX21_004011"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HDV1989130.1"
                     /translation="MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQ
                     FNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG
                     KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH
                     SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRMIGEETKAQILE
                     REGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRV
                     GIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALE
                     AFKTLCLHEGIIPALESSHALAHALKMMRENPDKEQLLVVNLSGRGDKDIFTVHDILK
                     ARGEI"
     gene            complement(2148..3509)
                     /gene="trpCF"
                     /locus_tag="RHX21_004012"
     CDS             complement(2148..3509)
                     /gene="trpCF"
                     /locus_tag="RHX21_004012"
                     /EC_number="4.1.1.48"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional indole-3-glycerol-phosphate
                     synthase TrpC/phosphoribosylanthranilate isomerase TrpF"
                     /protein_id="HDV1989131.1"
                     /translation="MMQTVLAKIVADKAIWVETRKQQQPRASFQNEVQPSTRHFYDAL
                     QGARTAFILECKKASPSKGVIRDDFDPARIAAIYKHYASAISVLTDEKYFQGSFDFLP
                     IVSQIAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLAAVAHSLEMG
                     VLTEVSNEEELERAIALGAKVVGINNRDLRDLSIDLNRTRELAPKLGHNVTVISESGI
                     NTSAQVRELSHFANGFLIGSALMAHDDLHAAVRRVLLGENKVCGLTRGQDAKAAYDAG
                     AIYGGLIFVATSPRCVNVEQAQEVMAAAPLQYVGVFRNHDIADVVDKAKVLSLAAVQL
                     HGNEDQLYIDTLREALPAHVAIWKALSVGETLPARELQHVDKYVLDNGQGGSGQRFDW
                     SLLNGQSLGNVLLAGGLGADNCVEAAQTGCAGLDFNSAVESQPGIKDARLLASVFQTL
                     RAY"
     gene            complement(3510..5105)
                     /gene="trpD"
                     /locus_tag="RHX21_004013"
     CDS             complement(3510..5105)
                     /gene="trpD"
                     /locus_tag="RHX21_004013"
                     /EC_number="2.4.2.18"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008784940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional anthranilate synthase glutamate
                     amidotransferase component TrpG/anthranilate
                     phosphoribosyltransferase TrpD"
                     /protein_id="HDV1989132.1"
                     /translation="MADILLLDNIDSFTYNLADQLRSNGHNVVIYRNHIPAQTLIERL
                     ATMSNPVLMLSPGPGVPSEAGCMPELLTRLRGKLPIIGICLGHQAIVEAYGGYVGQAG
                     EILHGKASSIEHDGQAMFAGLTNPLPVARYHSLVGSNIPAGLTINAHFNGMVMAVRHD
                     ADRVCGFQFHPESILTTQGARLLEQTLAWAQQKLEPANTLQPILEKLYQAQTLSQQES
                     HQLFSAVVRGELKPEQLAAALVSMKIRGEHPNEIAGAATALLENAAPFPRPDYLFADI
                     VGTGGDGSNSINISTASAFVAAACGLKVAKHGNRSVSSKSGSSDLLAAFGINLDMNAD
                     KSRQALDELGVCFLFAPKYHTGFRHAMPVRQQLKTRTLFNVLGPLINPAHPPLALIGV
                     YSPELVLPIAETLRVLGYQRAAVVHSGGMDEVSLHAPTIVAELHDGEIKSYQLTAEDF
                     GLTPYHQEQLAGGTPEENRDILTRLLQGKGDAAHEAAVAANVAMLMRLHGHEDLQANA
                     QTVLEVLRSGSAYDRVTALAARG"
     gene            complement(5105..6667)
                     /gene="trpE"
                     /locus_tag="RHX21_004014"
     CDS             complement(5105..6667)
                     /gene="trpE"
                     /locus_tag="RHX21_004014"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HDV1989133.1"
                     /translation="MQTQKPTLELLTCEGAYRDNPTALFHQLCGDRPATLLLESADID
                     SKDDLKSLLLVDSALRITALGDTVTIQALSGNGEALLTLLDNALPAGVENEQLPNCRV
                     LRFPPVSPLLDEDARLCSLSVFDAFRLLQNLLNVPKEEREAMFFGGLFSYDLVAGFED
                     LPQLSAENNCPDFCFYLAETLMVIDHQKKSTRIQASLFAPNEEEKQRLTARLNELRQQ
                     LTEAAPPLPVVSVPHMRCECNQSDEEFGGVVRLLQKAIRAGEIFQVVPSRRFSLPCPS
                     PLAAYYVLKKSNPSPYMFFMQDNDFTLFGASPESSLKYDATSRQIEIYPIAGTRPRGR
                     RADGSLDRDLDSRIELEMRTDHKELSEHLMLVDLARNDLARICTPGSRYVADLTKVDR
                     YSYVMHLVSRVVGELRHDLDALHAYRACMNMGTLSGAPKVRAMQLIAEAEGRRRGSYG
                     GAVGYFTAHGDLDTCIVIRSALVENGIATVQAGAGVVLDSIPQSEADETRNKARAVLR
                     AIATAHHAQETF"
     misc_feature    complement(6689..6782)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00513"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Trp leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00513"
     gene            complement(6759..6803)
                     /gene="trpL"
                     /locus_tag="RHX21_004015"
     CDS             complement(6759..6803)
                     /gene="trpL"
                     /locus_tag="RHX21_004015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trp operon leader peptide"
                     /protein_id="HDV1989134.1"
                     /translation="MKAIFVLKGWWRTS"
     gene            6941..7822
                     /gene="yciV"
                     /locus_tag="RHX21_004016"
     CDS             6941..7822
                     /gene="yciV"
                     /locus_tag="RHX21_004016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-3' exoribonuclease"
                     /protein_id="HDV1989135.1"
                     /translation="MSDTNYAVIYDLHSHTTASDGCLTPEALVHRAVEMRVGTLAITD
                     HDTTAAIAPAREEISRSGLALNLIPGVEISTVWENHEIHIVGLNIDITHPLMCEFLAQ
                     QTERRNQRAQLIAERLEKAQIPGALEGAQRLAQGGAVTRGHFARFLVECGKASSMADV
                     FKKYLARGKTGYVPPQWCTIEQAIDVIHHSGGKAVLAHPGRYNLSAKWLKRLVAHFAE
                     HHGDAMEVAQCQQSPNERTQLAALARQHHLWASQGSDFHQPCPWIELGRKLWLPAGVE
                     GVWQLWEQPQNTTEREL"
     gene            7819..8439
                     /locus_tag="RHX21_004017"
     CDS             7819..8439
                     /locus_tag="RHX21_004017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HDV1989136.1"
                     /translation="MSQFFYIHPDNPQQRLINQAVEIVRKGGVIVYPTDSGYALGCKI
                     EDKNAMERICRIRQLPDGHNFTLMCRDLSELSTYSFVDNVAFRLMKNNTPGNYTFILK
                     GTKEVPRRLLQEKRKTIGMRVPSNPIAQALLEALGEPMLSTSLMLPGSEFTESDPEEI
                     KDRLEKQVDLIIHGGYLGQKPTTVIDLTDDTPVVVREGVGDVKPFL"
     gene            8540..9412
                     /gene="rluB"
                     /locus_tag="RHX21_004018"
     CDS             8540..9412
                     /gene="rluB"
                     /locus_tag="RHX21_004018"
                     /EC_number="5.4.99.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2605) synthase RluB"
                     /protein_id="HDV1989137.1"
                     /translation="MSEKLQKVLARAGHGSRREIESIIEAGRVSVDGKIAKLGDRVEV
                     TPGLKIRIDGHLISVRESAEQICRVLAYYKPEGELCTRNDPEGRPTVFDRLPKLRGAR
                     WIAVGRLDVNTCGLLLFTTDGELANRLMHPSREVEREYAVRVFGQVDDAKLRDLSRGV
                     QLEDGPAAFKTIKFSGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDI
                     PLPKGLPRGGWTELDLAQTNYLRELVELPPETSSKVAVEKDRRRMKANQIRRAVKRHS
                     QVSGGRRSGGRNNG"
     gene            complement(9452..10042)
                     /gene="cobO"
                     /locus_tag="RHX21_004019"
     CDS             complement(9452..10042)
                     /gene="cobO"
                     /locus_tag="RHX21_004019"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="HDV1989138.1"
                     /translation="MSDERYQQRQQRVKEKVDARVAQAQDERGIIIVFTGNGKGKTTA
                     AFGTATRAVGHGKKVGVVQFIKGTWPNGERNLLEPHGVEFQVMATGFTWDTQNRESDT
                     AACREVWQHAKRMLADSSLDMVLLDELTYMVAYDYLPLEEVVQALNERPHQQTVIITG
                     RGCHRDILELADTVSELRPVKHAFDAGVKAQIGIDY"
     gene            complement(10039..10797)
                     /locus_tag="RHX21_004020"
     CDS             complement(10039..10797)
                     /locus_tag="RHX21_004020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciK family oxidoreductase"
                     /protein_id="HDV1989139.1"
                     /translation="MHYQPKQDLLNDRIILVTGASDGIGREAAMTYARYGATVILLGR
                     NEEKLRQVASHINEETGRQPQWFILDLLTCTSEDCQQLAQRITVNYPRLDGVLHNAGL
                     LGDVCPMSEQNPQVWQDVIQVNVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRA
                     NWGAYAASKFATEGMMQVLADEYQQRLRVNCINPGGTRTAMRASAFPTEDPQKLKTPA
                     DIMPLYLWLMGDDSRRKTGMTFDAQPGRKPGISQ"
BASE COUNT         2539 a         2894 c         2913 g         2570 t
ORIGIN      
        1 gcggaaaaat gacgtaagtt gacgttcgac cggggtaagc gaaacggtaa aaagataaat
       61 attaaatgaa tttaggattt ttccggcttc attaaagaaa gttaaaatgc cgccagcgga
      121 actggcggct gtgggattaa ctgcgcgtcg ccgctttcat cggttgtaca aaaactttca
      181 gtgccgccag cattttctct ggctcattaa tatgttgctc gatgatttta acaatggccg
      241 aaccagaaat cgcgcccgca gctcctgcat caatcgctgc ttttacctga tccggggcgg
      301 aaataccaaa cccctgcaat ggaggtgcag cgttgtactc tttcagcttc gcaaccagat
      361 gattgagggg taacgcggcg cggttttctg cgccggtcac gcccgctcgt gacagcaaat
      421 aggtgtaacc acgaccgtaa gaggctatct ggcgcagcag gtcgtcatcg gcatttggcg
      481 ggcagatgaa gataggtgcg acattatggc gcaacgcggc ctggcggaag ggcgcggact
      541 cttcaattgg cacatcggca accagcaccg aatcgacgcc gactttctcg cactgggcat
      601 aaaactcatc aatgcctttg ttaaacacca gattggcata catcaacagg ccaatgggaa
      661 tggtcgggtg tttctggcga atcagtgcca gcatttcaaa acattgtgcc ggagtcacac
      721 ctgccgcaaa ggcgcgcaga gtggcgtttt gaatcgtcgg gccatccgcc agtgggtcgg
      781 agaaggggat acctaactcc agcgcgtcag caccggcttc aattagcgta tcgataattt
      841 tcaatgactg ctcaatgccc ggatcaccga gcgtgacgaa aggaacgaat gcgccttctt
      901 tgcgctcctt caactgggca aacagagatt cgtagcgttc catcagattt cccctcgtgc
      961 tttcaaaata tcgtgaacgg tgaagatgtc tttatcgccg cgaccggaaa ggttaaccac
     1021 cagtagctgc tctttatccg ggttttcgcg catcattttc aacgcatggg ccagggcgtg
     1081 ggaggattcc agcgccggga tgatcccttc gtgcaggcac agcgttttga aggcttcaag
     1141 ggcttcatca tcggtaatag acacgtaatc agcgcgtcca gtgctgttaa gatacgcgtg
     1201 ttgtgggccg acagacggga aatccagtcc ggcggagatg gagtaagatt cttcaatctg
     1261 cccgtcttcg gtttgcatca tcggcgcttt cataccgaaa tagatgccca cgcgaccatg
     1321 ttttaacggt gcgccgtgct cgccagtttc gataccgtga ccacctggct ccacaccaat
     1381 caggccgacg ttggtttcat tgatgaaatc agcaaacatg ccgatggcat tcgaaccgcc
     1441 gccaacacag gcgataacgg catccggcag gcgaccttct ctttccagaa tctgcgcttt
     1501 ggtttcttcg ccaatcatcc gctgaaactc acgcacaatg gtcggataag gatgcgggcc
     1561 agctgcggtg cccagcatat agtgcgcggt ttcgtaacta ccggaccagt cgcgcagcgc
     1621 ctcgttacag gcatctttca gcgtcgcgga accgctatgc accgggatca cttccgcacc
     1681 cattaagcgc atacgaaaaa cgttaggcga ctggcgttct acgtctttgg cacccatata
     1741 aatacggcat ttcaggccga gcagggcgct ggcaagggcc gacgccacgc catgctgacc
     1801 ggcaccggtt tcggcgatga tttcggtttt acccatccgc ttcgccagta aagcctgacc
     1861 gagcacctgg ttagttttat gcgcgccgcc gtgcagcaaa tcttcacgct tgagatacag
     1921 agtggtgttc gtcccggctg taatgttctg gcatttggtc agcgcggttg gacgcccggc
     1981 atagtttttc agcaggtcgt tgaactgagc ctgaaattca ggatcttttt gcgcactgac
     2041 aaaagcttct tccagctggc gcagagcagg catcaggatt tgtggcacgt acatgccgcc
     2101 aaactcacca aaataggggt taagtaatgt tgtcattgtt cctttcctta atatgcgcgc
     2161 agcgtctgga aaaccgaggc caaaagacgt gcgtctttga tgcccggttg cgactctaca
     2221 gcagaattaa aatcaagtcc ggcgcagccg gtttgtgccg cttccacgca gttatctgcg
     2281 cctaagcccc ccgccagcag aacgttgcca agcgattgac catttaatag tgaccagtcg
     2341 aaacgttgcc cgcttccacc ctggccgttg tctaaaacat atttatcaac gtgctgaagc
     2401 tcgcgggcgg gcagggtttc accgacgctt aatgctttcc agatggcaac gtgtgctggc
     2461 agagcttcac gcagcgtatc gatatacagc tgatcttcat taccatgcag ttgcactgcc
     2521 gccagcgata acaccttagc tttgtccacc acatcggcaa tatcgtgatt gcggaacacg
     2581 ccaacatact gcaacggtgc cgcagccatc acttcctgcg cctgttcaac gttgacgcaa
     2641 cgcggtgatg tcgcaacaaa aatcaaccca ccgtaaatcg cgcccgcgtc ataagctgct
     2701 ttagcatctt gcccacgcgt caggccacat actttattct cacccagcaa cacccggcgc
     2761 acggcggcgt gcaaatcgtc atgggccatc aacgccgaac caatcagaaa accgttagcg
     2821 aagtggctta actcgcgcac ctgagcggaa gtattgatgc cggattcgct gattaccgtt
     2881 acgttgtgcc ccagtttcgg cgcaagctcg cgggtacggt tgagatcaat cgacaaatcc
     2941 cgcagatcgc ggttgttgat gccaacgacc tttgccccca atgcaatggc acgctccagt
     3001 tcctcttcat tactgacttc ggtcagcaca cccatctcca gactgtgggc gacggcggca
     3061 agctggcgat attgttcgtc atccagtact gaaagcatta ataagcaggc atcagcctgg
     3121 taatagcgcg ccagatagat ctggtaagga tcgataatga agtctttaca taaaatcggc
     3181 tgcggggcga tttggctgac gatggggagg aaatcaaagc tcccctgaaa atatttctca
     3241 tcagtcagca ccgaaattgc cgaagcgtaa tgtttataaa tggcggcaat gcgtgctgga
     3301 tcgaaatcat cacggatcac gccttttgac ggcgacgctt tcttgcactc cagaataaac
     3361 gccgtgcgcg caccctgtag cgcatcataa aaatgtcgcg tgctcggctg aacctcattc
     3421 tgaaaactgg cccgcggttg ctgctgtttg cgggtttcta cccaaatcgc cttgtctgcg
     3481 acgattttcg ctaaaacggt ttgcatcatt taccctcgtg ccgccagcgc ggtaactctg
     3541 tcgtaagcgg aaccactgcg cagtacctca agaacggttt gcgcattggc ttgcagatct
     3601 tcatggccat gcaggcgcat taacatggcg acgttcgcag cgacggctgc ttcatgggcg
     3661 gcgtcgcctt taccttgtaa caaacgtgtt aaaatgtcac ggttttcttc cggtgttccg
     3721 cctgccagtt gctcctggtg gtagggtgtc aggccaaaat cttcagcggt caattgatag
     3781 ctcttaattt cgccgtcatg cagctcggca acgattgtcg gcgcgtgtaa tgaaacttca
     3841 tccatcccgc cgctgtgcac caccgccgcg cgttgatacc ccagcacgcg caaggtttcg
     3901 gcaatcggca gcaccagttc cggactataa acaccaatta acgccagcgg cggatgcgcc
     3961 gggttaatca atggccccag cacattgaac agggtgcggg tttttagttg ctggcgaacc
     4021 ggcattgcat ggcgaaatcc ggtgtgatat ttcggtgcaa agaggaaaca tacgcctaac
     4081 tcatccagcg cctggcgcga tttatcggcg ttcatatcaa gattaatacc gaacgccgcc
     4141 agcagatcgg acgaaccaga tttactggag acgctacggt tgccgtgttt cgccactttc
     4201 agcccacagg ccgcagcgac aaacgcactg gcggtagaaa tattgatact gttgctgccg
     4261 tcaccgccag taccgacgat atcagcaaac agataatccg ggcgcgggaa cggcgctgcg
     4321 ttttccagta gcgcggttgc tgccccggcg atctcgttcg ggtgctcacc gcgaattttc
     4381 atgctcacca gcgccgccgc cagttgttcc ggcttcagct cgccacgcac caccgctgaa
     4441 aacagctggt ggctttcttg ttggctaagc gtctgcgcct gatacagttt ttccagaatc
     4501 ggttgcagcg tgttggctgg ctctagtttc tgctgcgccc aggccagcgt ttgttccagc
     4561 aggcgagcgc cctgggtggt gagaatggat tccggatgga actggaatcc acaaacgcga
     4621 tccgcatcgt gacgtactgc catcaccatg ccattaaaat gggcgttgat ggttaaaccg
     4681 gccggaatgt tactgccaac cagcgagtga taacgcgcca ccggcagcgg gtttgttaat
     4741 ccggcaaaca tcgcctgacc gtcatgttca atgctcgacg ctttaccgtg aagaatttcg
     4801 cccgcctgac cgacatagcc cccgtaagct tcgacaattg cctgatgtcc gaggcaaatg
     4861 ccaataatgg gcagcttgcc acgcaagcgg gtgaggagtt ccggcataca accggcttcg
     4921 ctcggcacac cggggccagg agaaagcatc agtaccggat tgctcatggt cgccaggcgt
     4981 tcaattaagg tctgcgccgg aatatggttg cggtaaatca ccacgttatg cccattgctg
     5041 cgcaactgat ctgccaggtt gtacgtaaaa gagtcgatat tatcgagcag cagtatgtca
     5101 gccatcagaa agtctcctgt gcatgatgcg cggtggcaat agcgcgcagt acagcgcggg
     5161 ctttattacg ggtttcgtcg gcttccgact gcggaataga atcaaggact acgccagcac
     5221 cggcttgcac ggtggcgata ccgttttcca ccagcgccga gcggatcaca atgcaggtgt
     5281 cgagatcgcc gtgcgcggtg aaataaccta ccgcgccgcc gtagctgccg cggcgacgac
     5341 cttccgcctc ggcaattaac tgcatggcgc gcactttcgg cgcaccgctt aacgtcccca
     5401 tattcataca ggcgcggtaa gcgtgtaggg cgtcgagatc gtggcgcagc tcaccgacca
     5461 cgcgggagac caggtgcatc acgtaagagt aacggtcaac tttggtgagg tcggcgacgt
     5521 agcggctgcc gggggtgcaa atgcgtgcca gatcattacg ggcaagatcc accagcatca
     5581 gatgttcaga aagctcttta tgatcggtac gcatttccag ttcgatgcgg ctgtcgaggt
     5641 ctctgtccag cgagccatcg gcacgacgac cgcgtggacg tgttccggca atcgggtaga
     5701 tctcaatctg gcggctggtg gcgtcatact tgagcgaact ttccggcgac gcgccaaaca
     5761 gggtgaaatc attatcctgc ataaaaaaca tgtacgggct gggattactc tttttcagca
     5821 cgtaataggc cgccagcggt gacgggcagg gcagagagaa acggcgagat ggcaccacct
     5881 ggaaaatttc tccagcgcga atcgcttttt gcaacaaacg cactacgcca ccgaactctt
     5941 catcgctctg attacattca caacgcatat gcggcacgga aaccaccggc agcggcggcg
     6001 cggcttcggt cagttgctga cgtagttcgt tcaggcgagc agtgagacgt tgtttttctt
     6061 cttcattcgg agcaaacagg ctggcctgaa tacgggtgct ttttttctga tggtcaatca
     6121 ccatcagagt ttcagcgaga taaaaacaga aatcagggca gttattttcc gctgacagtt
     6181 gcggtaaatc ttcaaatccc gccacaaggt cataagagaa caggccgccg aagaacattg
     6241 cttctcgttc ttccttcggt acattcaaca gattctgcaa taaacggaaa gcgtcaaaaa
     6301 ccgaaaggga gcataagcga gcgtcttcat ccagcagtgg actgacaggg gggaagcgca
     6361 gcacacggca gtttggtaat tgttcatttt ccacacccgc aggcagggcg ttatccagta
     6421 gtgtcagcag ggcttcgccg ttgccggaaa gtgcctggat tgtgacagtg tcacctaaag
     6481 ctgtaatgcg cagcgcactg tctaccagta gcaggctttt taaatcatct ttgctgtcga
     6541 tatctgcgga ttccagcagc agcgttgccg gacgatcccc acacaactgg tgaaaaagcg
     6601 cggtgggatt gtcgcgataa gcgccttcgc aggttagcag ttcgagagtc ggtttttgtg
     6661 tttgcattgt tattctctaa ttttgttcaa aaaaaagccc gctcattagg cgggctgggt
     6721 atctgattgc tttacgcatg gtgaatacac tgcccgtttc aggaagtgcg ccaccaacct
     6781 ttcagtacga aaattgcttt cattgtcgat acccttttta cgtgaacttg cgtactagtt
     6841 aactagttcg atgattaatt gtcaacagct catttcagaa tatttgccag aaccgttatg
     6901 atgtcggcgc aaaaaacatt atccagaacg ggagtgcgcc ttgagcgaca cgaattacgc
     6961 agtgatttac gacctgcaca gccataccac agcttccgat ggctgcctga cgccagaagc
     7021 attggtgcac cgtgcagtcg agatgcgcgt cggcaccctg gcgatcaccg accatgacac
     7081 cacagctgca atcgcgccag caagagagga aatttcacgt tcgggactgg cgctgaatct
     7141 tattcccggc gtggaaattt ccacggtctg ggaaaatcat gaaattcata ttgtcgggct
     7201 gaatattgat attactcatc cgctaatgtg tgagttcctc gcgcagcaga cagaacggcg
     7261 caatcagcgg gcgcagctga ttgccgaaag acttgaaaaa gcgcaaatac ctggggcgct
     7321 ggaaggcgca caacgactgg cgcagggcgg cgcagtgacg cgcggtcatt ttgcgcgttt
     7381 ccttgttgag tgcggcaaag ccagttcaat ggcggatgtc tttaaaaagt atctggcgcg
     7441 cgggaaaacc ggatacgttc cgccacagtg gtgtacaata gaacaagcta ttgatgtcat
     7501 tcatcattct ggcggtaagg cggtgctagc tcatcctggg cggtacaatc ttagtgctaa
     7561 atggctgaaa agattggttg cgcattttgc cgaacaccac ggtgacgcga tggaagtcgc
     7621 gcagtgccag caatcgccca atgaacgtac ccagctggcg gcccttgcgc gtcagcatca
     7681 tttatgggca tcacaaggat ctgattttca tcagccatgc ccgtggatcg aactgggtcg
     7741 taaactctgg ctgcccgcag gcgttgaagg cgtctggcag ctatgggaac agccgcagaa
     7801 caccacagag agggaattat gagccagttt ttttatattc atcctgataa cccacagcaa
     7861 cgtctgatca accaggcggt ggagatcgtg cgtaaaggcg gggtgattgt ttatccaact
     7921 gattccggct atgcgctcgg ctgtaaaatt gaagataaaa acgcgatgga gcgtatttgt
     7981 cgtattcgcc agctgccgga cggtcacaac tttaccctga tgtgtcgcga tctttctgaa
     8041 ctctcgacct attcatttgt tgataacgtt gcgtttcgtt taatgaaaaa caacacgccg
     8101 ggcaactata ccttcatctt gaaggggacg aaggaagtgc cacgccgtct gttgcaggaa
     8161 aaacgcaaaa ccatcggtat gcgtgtgcct tctaacccga ttgcgcaggc gttgcttgaa
     8221 gcactgggcg aaccgatgct ttccacttcg ctaatgctgc caggcagcga atttaccgaa
     8281 tccgatcccg aagaaattaa agaccgtctg gaaaaacagg tggatttgat tatccacggc
     8341 ggctatctcg gacagaaacc gacaacggtt attgatctta ccgatgatac gccggtcgtg
     8401 gtgcgtgaag gcgtaggtga tgtgaagcct ttcttataag tgcgtaactc tgtatactac
     8461 gcggccttaa aatggcgcta tacggcgcca ttgattctcc tgttcgacgc ctgtgaaggc
     8521 gacaccaaaa ggaagctcta tgagcgaaaa attacagaaa gtgctggccc gcgctggcca
     8581 cggctcccgc cgtgaaatcg aatctattat tgaagccggt cgtgtgagtg ttgatggcaa
     8641 aattgctaaa ctcggcgatc gcgttgaagt tacccctggg ctgaaaattc gtatcgatgg
     8701 tcatctgatt tcggtacgtg agtccgctga acaaatttgt cgcgttctgg cctattacaa
     8761 accggaaggt gagttgtgta cccgtaacga tccggaaggg cgtccgacgg tgtttgaccg
     8821 tctgccaaag ctgcgtggcg cacgctggat tgccgtaggt cgtctggacg ttaacacctg
     8881 tggtctgctg ctgttcacca ccgatggtga actggcaaac cgtttaatgc atccaagccg
     8941 tgaagttgaa cgtgaatacg ccgtgcgtgt atttggtcag gttgacgacg cgaaactgcg
     9001 tgatttgagt cgtggcgtgc aactggaaga tggtccggca gcttttaaaa ccatcaagtt
     9061 cagcggcggc gaagggatca accagtggta caacgtgact ctgaccgaag gccgtaaccg
     9121 tgaagttcgt cgtctgtggg aagcggttgg tgtgcaggtg agccgcctga tccgtgttcg
     9181 ttacggtgat atcccactgc caaaaggtct gccacgcggt ggctggacgg agctggacct
     9241 cgcccagact aactatctgc gcgaactggt ggagcttccg ccagaaacca gctctaaagt
     9301 cgctgtagaa aaagaccgtc gtcgcatgaa ggctaatcag attcgtcgtg cggtgaaacg
     9361 tcacagtcag gtgagcggcg gtcgtcgttc tggcgggcgt aataacggtt aatcaaagta
     9421 tgccggacgt catatccggc atttttacag attaataatc aatccctatc tgcgctttta
     9481 caccggcatc aaacgcatgt ttgacggggc gtaattcact taccgtatct gccagttcaa
     9541 gaatatcccg atgacaacca cgacccgtga taatcaccgt ctgttgatgt ggacgttcat
     9601 ttaacgcctg caccacttct tccagtggca aatagtcata cgccaccata tacgtcagtt
     9661 catcaagcaa aaccatatcc agtgaggaat cagcaagcat ccgctttgca tgttgccaga
     9721 cttcgcggca ggcggcggta tcagactcgc ggttttgtgt atcccaggta aagcccgttg
     9781 ccatcacctg aaactcaacg ccatgtggct ccagcagatt gcgttcgcca ttaggccagg
     9841 tgcctttaat aaactgcacg acgcctactt tttttccgtg accaactgcg cgtgttgccg
     9901 taccaaatgc cgcggtggtt ttgccttttc cattgccggt aaagacgatg ataataccgc
     9961 gttcatcctg ggcctgggcc acacgagcat ctactttttc tttcactcgc tgctgacgct
    10021 gttggtagcg ttcatcactc attgggaaat tcctggttta cggcccggtt gggcgtcaaa
    10081 ggtcatgccg gttttacggc ggctgtcatc gcccatcagc cagaggtaga gcggcatgat
    10141 atcagcgggt gttttaagtt tctgtggatc ttcggtcggg aaggcgctgg cacgcattgc
    10201 ggtgcgcgta ccgcctgggt taatgcagtt gacgcgcagg cgctgctgat attcatcggc
    10261 cagtacctgc atcatccctt cggtggcaaa tttcgacgct gcatatgcgc cccagttggc
    10321 tcgtccctga cgtccaacgc ttgatgaagt aaagaccagt gaaccggcgt ccgatttgag
    10381 taataaagga agcagtgcct gggtgagcat aaaggtggca ttaacgttga cctgtatgac
    10441 gtcctgccag acctgtggat tttgttcgct cattgggcaa acatcgccga gcaatccggc
    10501 attatgcaaa acaccatcca gacgcggata attaacggta atgcgctgtg ccagttgttg
    10561 gcaatcttcg gacgtgcagg tcagcaaatc gagaataaac cactgtggct gacgtccagt
    10621 ttcttcgttt atgtggctgg ctacctgacg taatttttct tcattacggc ccaacagaat
    10681 cactgtcgca ccatagcgtg catacgtcat cgcggcttca cggccaatcc catcgctggc
    10741 tcccgtcacc aggataatgc gatcattgag taaatcttgt tttggctggt aatgcatggc
    10801 tactcctcaa cgacgttgtc tgtcgtgctg ccagtgtact ttatgacttt ggggctttat
    10861 gcctgaaaca gaagggcatt tcaatcagcc tggggcgata acaccgcaaa atggat
//
LOCUS       DAPGUL010000140        10790 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.143, whole genome shotgun sequence.
ACCESSION   DAPGUL010000140 DAPGUL010000000
VERSION     DAPGUL010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10790
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.143"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(86..1750)
                     /gene="glnS"
                     /locus_tag="RHX21_004021"
     CDS             complement(86..1750)
                     /gene="glnS"
                     /locus_tag="RHX21_004021"
                     /EC_number="6.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase"
                     /protein_id="HDV1989140.1"
                     /translation="MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGH
                     AKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVESIKNDVEWLGFHWSGNVRYSSD
                     YFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEK
                     MRAGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCI
                     SDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNL
                     LVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIRE
                     DLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRAD
                     FREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADG
                     RKVKGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSL
                     KDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDTWAKVGE"
     gene            complement(1953..3899)
                     /gene="nagE"
                     /locus_tag="RHX21_004022"
     CDS             complement(1953..3899)
                     /gene="nagE"
                     /locus_tag="RHX21_004022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetyl glucosamine transporter subunit
                     IIABC"
                     /protein_id="HDV1989141.1"
                     /translation="MNILGFFQRLGRALQLPIAVLPVAALLLRFGQPDLLNVAFIAQA
                     GGAIFDNLALIFAIGVASSWSKDSAGAAALAGAVGYFVLTKAMVTINPEINMGVLAGI
                     ITGLVGGAAYNRWSDIKLPDFLSFFGGKRFVPIATGFFCLVLAAILGYVWPPVQHAIH
                     AGGEWIVSAGALGSGIFGFINRLLIPTGLHQVLNTIAWFQIGEFTNAAGTVFHGDINR
                     FYAGDGTAGMFMSGFFPIMMFGLPGAALAMYFAAPKERRPMVGGMLLSVAVTAFLTGV
                     TEPLEFLFMFLAPLLYLLHALLTGISLFVATLLGIHAGFSFSAGAIDYALMYNLPAAS
                     QNVWMLLVMGVVFFAIYFVVFSLVIRMFNLKTPGREDKEDEIVTEEANSNTEEGLNQL
                     ATNYIAAVGGTDNLKAIDACITRLRLTVADSARVNDTMCKRLGASGVVKLNKQTIQVI
                     VGAKAESIGDAMKKVVARGPVAAASAEATPATAAPVAKPQAVPNAVSIAELVSPITGD
                     VVALDQVPDEAFASKAVGDGVAVKPTDKIVVSPAAGTIVKIFNTNHAFCLETEKGAEI
                     VVHMGIDTVALEGKGFKRLVEEGAQVSAGQPILEMDLDYLNANARSMISPVVCSNIDD
                     FSGLIIKAQGHVVAGQTPLYEIKK"
     gene            4232..5032
                     /gene="nagB"
                     /locus_tag="RHX21_004023"
     CDS             4232..5032
                     /gene="nagB"
                     /locus_tag="RHX21_004023"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008805656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDV1989142.1"
                     /translation="MRLIPLTTAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGT
                     PMTTYKALVEMHKAGQVSFKHVVTFNMDEYVGLPKEHPESYYSFMHRNFFDHVDIPAE
                     NINLLNGNAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIK
                     TLTHDTRVANSRFFDNDVNQVPKYALTVGVGTLLDAEEVMILVLGSQKALALQAAVEG
                     CVNHMWTISCLQLHPKAIMVCDEPSTMELKVKTLRYFNELEAENIKGL"
     gene            5092..6240
                     /gene="nagA"
                     /locus_tag="RHX21_004024"
     CDS             5092..6240
                     /gene="nagA"
                     /locus_tag="RHX21_004024"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDV1989143.1"
                     /translation="MYALTQGRIFTGHEFLDDHAVVIADGLIKSVCPVAELPPEIEQR
                     SLNGAILSPGFIDVQLNGCGGVQFNDTAEAVSVETLEIMQKANEKSGCTNYLPTLITT
                     SDELMKQGVRVMREYLAKHPNQALGLHLEGPWLNLVKKGTHNPNFVRKPDAALVDFLC
                     ENADVITKVTLAPEMVPAEVISKLANAGIVVSAGHSNATLKEAKAGFRAGITFATHLY
                     NAMPYITGREPGLAGAILDEADIYCGIIADGLHVDYANIRNAKRLKGDKLCLVTDATA
                     PAGANIEQFIFAGKTIYYRNGLCVDENGTLSGSSLTMIEGVRNLVEHCGIALDEVLRM
                     ATLYPARAIGVEKRLGTLAAGKVANLTAFTPDFKITKTIVNGNEVVTQ"
     gene            6249..7469
                     /gene="nagC"
                     /locus_tag="RHX21_004025"
                     /gene_synonym="nagR"
     CDS             6249..7469
                     /gene="nagC"
                     /locus_tag="RHX21_004025"
                     /gene_synonym="nagR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NagC"
                     /protein_id="HDV1989144.1"
                     /translation="MTPGGQAQIGNVDLVKQLNSAAVYRLIDQYGPISRIQIAEQSQL
                     APASVTKITRQLIERGLIKEVDQQASTGGRRAISIVTETRNFHAIGVRLGRHDATITL
                     FDLSSKVLAEEHYPLPERTQQTLEHALLNAIAQFIDSYQRKLRELIAISVILPGLVDP
                     DSGKIHYMPHIQVENWGLVEALEERFKVTCFVGHDIRSLALAEHYFGASQDCEDSILV
                     RVHRGTGAGIISNGRIFIGRNGNVGEIGHIQVEPLGERCHCGNFGCLETIAANAAIEQ
                     RVLNLLKQGYQSRVPLDDCTIKTICKAANKGDSLASEVIEYVGRHLGKTIAIAINLFN
                     PQKIVIAGEITEADKVLLPAIESCINTQALKAFRTNLPVVRSELDHRSAIGAFALVKR
                     AMLNGILLQHLLEN"
     gene            7517..8269
                     /gene="nagD"
                     /locus_tag="RHX21_004026"
     CDS             7517..8269
                     /gene="nagD"
                     /locus_tag="RHX21_004026"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide monophosphatase NagD"
                     /protein_id="HDV1989145.1"
                     /translation="MTIKNVICDIDGVLMHDNVAVPGAAEFLHGIMDKGLPLVLLTNY
                     PSQTGQDLANRFATAGVDVPDSVFYTSAMATADFLRRQEGKKAYVVGEGALIHELYKA
                     GFTITDVNPDFVIVGETRSYNWDMMHKAAYFVANGARFIATNPDTHGRGFYPACGALC
                     AGIEKISGRKPFYVGKPSPWIIRAALNKMQAHSEETVIVGDNLRTDILAGFQAGLETI
                     LVLSGVSSLDDIDSMPFRPSWIYPSVAEIDVI"
     gene            8526..10190
                     /gene="asnB"
                     /locus_tag="RHX21_004027"
     CDS             8526..10190
                     /gene="asnB"
                     /locus_tag="RHX21_004027"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001724523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase B"
                     /protein_id="HDV1989146.1"
                     /translation="MCSIFGVFDIKTDAVELRKKALELSRLMRHRGPDWSGIYASDNA
                     ILAHERLSIVDVNAGAQPLYNQQKTHVLAVNGEIYNHQALRAEYGDRYQFQTGSDCEV
                     ILALYQEKGPEFLDDLQGMFAFALYDSEKDAYLIGRDHLGIIPLYMGYDEHGQLYVAS
                     EMKSLVPVCRTIKEFPAGSYLWSQDGEIRSYYHRDWFDFDAVKDNVTDKNELRQALED
                     SVKSHLMSDVPYGVLLSGGLDSSIISAITKKYAARRVEDQERSEAWWPQLHSFAVGLP
                     GSPDLKAAQEVANHLGTVHHEIHFTVQEGLDAIRDVIYHIETYDVTTIRASTPMYLMS
                     RKIKAMGIKMVLSGEGSDEVFGGYLYFHKAPNAKELHEETVRKLLALHMYDCARANKA
                     MSAWGVEARVPFLDKKFLDVAMRINPQDKMCGNGKMEKHILRECFESYLPASVAWRQK
                     EQFSDGVGYSWIDTLKEVAAQQVSDQQLETARFRFPYNTPTSKEAYLYREIFEELFPL
                     PSAAECVPGGPSVACSSAKAIEWDEAFKKMDDPSGRAVGVHQSAYK"
     gene            10571..10647
                     /locus_tag="RHX21_004028"
     tRNA            10571..10647
                     /locus_tag="RHX21_004028"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10605..10607,aa:Met,seq:cat)
     gene            10656..10740
                     /locus_tag="RHX21_004029"
     tRNA            10656..10740
                     /locus_tag="RHX21_004029"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10690..10692,aa:Leu,seq:tag)
BASE COUNT         2663 a         2793 c         2754 g         2580 t
ORIGIN      
        1 gccgcagagt gcggcgtttg ggattgtttg ctatttcttg ccggatgcga cgtaaatgcc
       61 tcacccggcc tggtagaact taaaattact cgcctacttt cgcccaggta tcacgcagcc
      121 caacggtgcg gttaaatacc ggtttttccg ctgtggaatg gcggctgtcg aggcagaagt
      181 aaccttcacg ctcaaactgg aatgctttac ccgcaaccgc atctttcagc gacggttcag
      241 caaagccctg tttgatcacc agcgattccg ggttaatcac cgacaggaaa tcatccgcag
      301 caccagggtt cggcacgctg aacagacggt cgtacagacg gatttcaacc ggcagcgcat
      361 gtgccgcgct cacccagtga ataacacctt tgactttacg accatctgcc ggatctttgc
      421 ttaaggtgtc ggcgtcataa gtacagaaga tggtggtgat attgccttcg gcatctttct
      481 ccacgcgttc agccttaatg acgtaagcat tacgcagacg cacttcttta cccagcacca
      541 gacgtttgta ctgcttgtta gcttcttcgc ggaaatcggc gcgatcgatc caaatctcac
      601 cgctaaacgg cacctgacga ctccccattt ccggtttgtt cggatggttc ggcatggtga
      661 ccatttcgcc ttcgccctga tagttttcga taaccagttt caccggatcg ataaccgcca
      721 ttgcgcgcgg cgcattttcg ttgagatctt cacggatgca ggattccagc gatgccatct
      781 caatggtgtt gtcctgcttg gtcacgccga tgcgtttgca gaactcacga atagaagcag
      841 cagtgtaacc acgacgacgc agaccggaaa tggtcggcat acgcgggtca tcccagcctt
      901 caacgtgctt gtcggtcacc agcaggttca gcttacgctt ggacatcaca gtgtattcca
      961 gattcaggcg cgagaattcg tactggcgcg ggtgaacagg aatggtgatg ttgtccagca
     1021 cccagtcgta caggcgacgg ttgtcctgga actcaagcgt acacagagag tgcgtaatac
     1081 cttccagggc atcgctgatg cagtgggtga agtcgtacat cgggtagatg caccacttgt
     1141 tgccagtctg gtggtgttca gcaaatttaa tacggtacag caccggatcg cgcatcacga
     1201 taaacggtga agccatgtcg attttcgcac gcaggcaggc tttaccttct tcaaaaccac
     1261 cggcacgcat tttttcgaac agcgccaggt tctcttcaac gctgcggtcg cggtacgggc
     1321 tgtttttacc cggttgcgtc agggtgccgc ggtattcgcg gatctgttcc ggcgtcagtt
     1381 catcaacgta cgccaggcct ttattgatca gttcgatcgc ataggcgtgg agctgatcaa
     1441 aataatcgga ggagtaacgg acgttaccag accagtgaaa acctaaccac tctacgtcgt
     1501 ttttgatcga ctcaacatac tcgatatctt cttttaccgg gttagtgtcg tcgaaacgca
     1561 ggttgcactg gcctttatag tcctgggcga tcccgaagtt caggcagata gatttcgcat
     1621 ggccaatatg cagatagcca ttcggctccg gcgggaaacg ggtgtgtact gtggtgtgct
     1681 taccactggc cagatcttca tcgatgatct gacggataaa gttagtcggg cgggcttctg
     1741 cctcactcat cgtggattcc tcaaagcgta aacaacgtat aacggcgtat gatcttataa
     1801 gcgggacagg ctgacaactg ttagtttttt aaaattgata atctaacaag gattatgggg
     1861 atgattgatg aaaaaaaaag cggcagagaa gatctccacc gcttgtcatt gttggatgcg
     1921 acgctcaagc gtcgcatcag gcataaagca gattactttt tgatttcata cagcggtgtt
     1981 tgacccgcca caacatggcc ctgagcttta atgatcaagc cactgaaatc gtcgatattg
     2041 ctgcaaacca ccgggctaat catcgagcgg gcgttagcgt tcaggtaatc cagatccatt
     2101 tccagaatcg gttgccctgc gcttacctgc gcaccctctt ccaccagacg tttaaagcct
     2161 ttaccttcca gcgctacggt gtcgataccc atatggacga cgatctccgc gcctttttcg
     2221 gtttccaggc agaacgcgtg gttggtgttg aagattttca cgattgtccc tgcggctggt
     2281 gatacgacga ttttatctgt cggtttcacc gccacaccgt cacccaccgc tttgctggcg
     2341 aatgcttcgt caggaacctg atccagtgcc acgacatcac cggtaatcgg cgataccagc
     2401 tccgcgatag ataccgcgtt tggtacagcc tgcggttttg ctacaggcgc ggcagttgcc
     2461 ggagttgctt cagctgacgc agcggctacc ggaccacggg caacgacttt cttcatcgca
     2521 tcgccgatgg attctgcttt cgcgccaaca atcacctgaa tagtctgttt gttcagtttc
     2581 actacaccag aagcacccag acgtttacac atcgtatcgt tgacgcgggc agagtcagcc
     2641 acggtcaggc gcagacgggt gatacaggcg tcaattgctt tcaggttgtc agtgccgcca
     2701 accgcagcaa tatagttggt cgccagttga ttgaggcctt cttcagtgtt gctgttggct
     2761 tcttcagtaa cgatctcgtc ttctttatct tcacgacccg gcgttttcag gttgaacatg
     2821 cggataacca aactgaacac cacgaagtag atagcgaaga agacaacacc cataaccagc
     2881 agcatccaga cgttctggct ggcggccggc aggttataca tcaacgcgta gtcgatagcc
     2941 cccgcagaga aagagaagcc agcatggata cccagcagtg ttgccacaaa caggctgata
     3001 ccggtcagca gtgcgtgcag gaggtacagc agcggtgcaa ggaacatgaa caggaattcc
     3061 agcggctcag tcacaccggt caggaacgca gtaacagcaa cagaaagcag catcccgcca
     3121 accatcggac gacgctcttt cggtgctgcg aagtacatcg ccagcgccgc acccggcaga
     3181 ccgaacatca taatcgggaa gaagccggac atgaacatcc ccgcggtgcc gtcaccggca
     3241 tagaagcggt tgatatcacc gtggaaaacc gtacccgccg cgttggtgaa ttcaccaatc
     3301 tggaaccagg cgatggtgtt cagcacctga tgcagaccgg ttgggatcag cagacggttg
     3361 atgaaaccaa agataccgga acccagcgcg cccgcagaaa cgatccactc gcctcctgca
     3421 tggatagcgt gctgtaccgg cggccagacg taaccaagaa tggccgccag caccaggcag
     3481 aagaagccgg tggcaatcgg cacaaagcgt ttgccgccga agaaactcag gaagtccggc
     3541 agtttaatat cggaccaacg gttataggct gcgccaccaa ccagaccggt aatgataccc
     3601 gccagtacac ccatgttaat ttctgggttg atggtcacca tcgctttggt taacacaaag
     3661 taacctaccg cacccgccag cgccgccgca cctgcgctgt ctttcgacca gctggatgcc
     3721 acaccgatgg cgaagattaa tgcgaggtta tcaaaaatcg caccgcccgc ctgggcaata
     3781 aacgcaacgt taagtaaatc tggctgaccg aatcgcagca acagtgccgc caccggcagc
     3841 accgcgatag ggagctgtaa cgccctaccg agtcgctgga aaaaacctaa aatattcatc
     3901 ttattccccc tacgagaacc ctatttggct cgtttaaagc cgtattttta ttttgctgca
     3961 aattgtactg ccgatgttct gtaatcagat tgttagatca tctgctacag agtgtgtgaa
     4021 aatttaattc gtatcgcaaa ttaaacgcgt gtcttttgtg agttttgtca ccaaatatcg
     4081 ttatcatcac tcccttttac tggctaaacc agaaaactta ttttatcatt caaaaaatca
     4141 ggtcggattg acgcctgtct gcgcaaatcc aggttacgct taaagatgcc taatccgcca
     4201 acggcttaca ttttacttat tgaggtgaat aatgagactg atccccctga ctaccgctga
     4261 acaggtcggc aaatgggctg ctcgccatat cgtcaatcgt atcaatgcgt tcaaaccgac
     4321 tgccgatcgt ccgtttgttc tgggcctgcc gactggcggc acgccgatga ccacctataa
     4381 agcgttagtc gaaatgcata aagcaggcca ggtcagcttt aagcacgttg tcaccttcaa
     4441 catggacgaa tatgtcggtc tgccgaaaga gcatccggaa agctactaca gctttatgca
     4501 ccgtaatttc ttcgatcacg ttgatattcc agcagaaaac atcaaccttc tcaacggcaa
     4561 cgccccggat atcgacgccg aatgccgcca gtatgaagaa aaaatccgtt cttacggaaa
     4621 aattcatctg tttatgggcg gtgtaggtaa cgacggtcat attgcattta acgaaccggc
     4681 gtcttctctg gcttctcgta ctcgtatcaa aaccttgact catgacactc gcgtcgcgaa
     4741 ctctcgtttc tttgataacg atgtcaatca ggtgccaaaa tatgccctga ctgtcggtgt
     4801 tggtacattg ctggatgccg aagaagtgat gattctggtg ctgggtagcc agaaagcact
     4861 ggcactgcag gctgcagttg aaggttgcgt gaaccacatg tggaccatca gctgtctgca
     4921 actgcatcca aaagcgatca tggtgtgcga tgaaccttcc accatggagc tgaaagttaa
     4981 gactttaaga tatttcaatg aattagaagc agaaaatatc aaaggtctgt aattgttatc
     5041 cctgccctgg ctccttgctc agggcaatat ttttaaaaat cgggggtcag aatgtatgca
     5101 ttaacccagg gccggatctt taccggccac gaatttcttg atgaccacgc ggttgttatc
     5161 gctgatggcc tgattaaaag cgtctgtccg gtagcggaac tgccgccaga gatcgaacaa
     5221 cgttcactga acggggccat tctctccccc ggttttatcg atgtgcagtt aaacggctgc
     5281 ggcggcgtac agtttaacga caccgctgaa gcggtcagcg tggaaacgct ggaaatcatg
     5341 cagaaagcca atgagaaatc aggctgtact aactatctgc cgacgcttat caccaccagc
     5401 gatgagctga tgaaacaggg cgtgcgcgtt atgcgcgagt acctggcaaa acatccgaat
     5461 caggcgttag gtctgcatct ggaaggtccg tggctgaatc tggtaaaaaa aggcacccat
     5521 aatccgaatt ttgtgcgtaa gcctgatgcc gcgctggtcg atttcctgtg tgaaaacgcc
     5581 gacgtcatta ccaaagtgac cctggcaccg gaaatggttc ctgcggaagt catcagcaaa
     5641 ctggcaaatg ccgggattgt ggtttctgcc ggtcactcca acgcgacgtt gaaagaagcg
     5701 aaagccggtt tccgcgcggg gattaccttt gccacccatc tgtacaacgc gatgccgtat
     5761 attaccggtc gtgaaccggg cctggcgggc gcgatcctcg acgaagctga catttattgc
     5821 ggtattatcg ctgatggcct gcatgttgat tacgccaaca ttcgtaacgc taaacgcctt
     5881 aaaggcgaca aactgtgtct ggttaccgac gccaccgcgc cagcaggtgc caacattgaa
     5941 cagttcattt ttgcgggtaa aacaatatac taccgtaacg gactttgtgt ggatgagaac
     6001 ggtacgttaa gcggttcatc cttaaccatg attgaaggcg tgcgtaatct ggtcgaacat
     6061 tgcggtatcg cactggatga agtgctgcgt atggcgacgc tctatccggc gcgtgcgatt
     6121 ggcgttgaga aacgtctcgg cacactcgcc gcaggtaaag tagccaacct gaccgcattc
     6181 acacctgatt ttaaaatcac caagaccatc gttaacggta acgaggtcgt aactcaataa
     6241 gagaaagtat gacaccaggc ggacaagctc agataggtaa tgttgatctc gtaaaacagc
     6301 ttaacagcgc ggcggtttat cgcctgattg accagtacgg gccaatctcg cggattcaga
     6361 ttgccgagca aagccagctt gcccccgcca gcgtaaccaa aattacgcgt cagcttatcg
     6421 aacgcgggct gatcaaagaa gttgatcagc aggcctccac cgggggccgc cgcgctatct
     6481 ccatcgtcac cgaaacccgc aatttccacg caatcggcgt acggcttggt cgtcacgacg
     6541 ccaccatcac cctgtttgat ctcagcagca aagtgctggc agaagaacat tacccgctgc
     6601 cggaacgtac ccagcaaacg ctggaacatg ccctgttgaa tgccattgct cagtttattg
     6661 atagctacca gcgcaaactg cgcgagctga tcgcgatttc ggtgatcctg ccagggcttg
     6721 ttgacccgga cagcggcaaa attcattaca tgccgcatat tcaggtagaa aactgggggc
     6781 tggtagaagc actggaagaa cgttttaaag tgacctgttt cgttggtcac gatatccgta
     6841 gtctggcgct ggcggagcac tacttcggtg caagtcagga ttgcgaagac tccattctgg
     6901 tgcgtgtcca tcgcggaacc ggggccggga ttatctctaa cgggcgcatt tttattggcc
     6961 gcaacggcaa cgtcggtgaa attggccata ttcaggtcga accgctgggt gaacgctgcc
     7021 actgcggcaa ctttggctgc ctggaaacta tcgctgccaa cgccgctatt gaacaacggg
     7081 tgttgaatct tttaaagcag ggctaccaga gccgcgtgcc gctggacgac tgcaccatca
     7141 aaactatctg caaagccgcg aacaaaggcg atagcctggc ctcggaagtg attgagtatg
     7201 tcggtcgtca tctgggcaaa accatcgcca ttgctatcaa cttatttaat ccgcaaaaaa
     7261 ttgttattgc cggtgaaatc accgaagccg ataaagtgct gctccctgct attgaaagct
     7321 gcattaatac ccaggcgctg aaggcgtttc gcactaatct gccggtggta cgttctgagc
     7381 tggatcaccg ctcggcaatc ggcgcttttg cgctggtaaa acgcgccatg ctcaacggta
     7441 ttttgctcca gcatttgctg gaaaattaat gtgcttttat agtggcgctt attgttgtca
     7501 atattctggg tagtccatga ccattaaaaa tgtaatttgc gatatcgacg gcgtgctgat
     7561 gcacgataac gtcgccgtac cgggtgcagc ggaatttttg cacgggatta tggataaagg
     7621 cctgccgctg gtgttgctga ccaactatcc ttcgcagacc gggcaagatc tggcgaaccg
     7681 ctttgccact gccggtgtcg atgtgccgga tagcgtgttt tatacctctg cgatggcgac
     7741 tgccgatttc ctgcgtcgcc aggaaggcaa gaaagcgtat gtggtgggcg aaggcgcact
     7801 gattcatgaa ctgtacaaag ccggtttcac tattaccgat gtgaaccctg attttgtgat
     7861 tgttggcgaa acgcgttcct acaactggga catgatgcat aaagcggcct atttcgtcgc
     7921 taacggtgca cgctttatcg ccaccaaccc ggacacccac gggcgcggtt tttatcccgc
     7981 ttgtggcgcg ttgtgtgcag ggattgagaa aatctccggg cgcaaaccgt tctatgttgg
     8041 taagcccagc ccgtggatca tccgcgcggc attaaacaaa atgcaggcgc attcggaaga
     8101 aacggtgatt gtcggcgata acttgcgtac cgatattctg gcgggcttcc aggcgggtct
     8161 ggagacgatt ctggtgcttt ctggtgtttc gtcgctcgac gatatcgaca gtatgccgtt
     8221 ccgcccaagt tggatttacc catcggtcgc tgaaatcgac gttatctgaa tagcaaccac
     8281 gtctgcggac gtggtttctt atttttaccc atcattaaaa tcatcccatt caataaaacc
     8341 cgtcaaaaat tatcgatcca tcaataaata cgccaccaca ccctatcctt tttcacaaat
     8401 cagcaatcac cattacgttt tttatttttt caccgccaaa tcgcttgcgc acagtgctgc
     8461 tttgcggcat ttttttaaac aagcaaacac aacaagcaac aaataccaag ttaacggaga
     8521 aggttatgtg ttcaattttt ggcgtattcg atatcaaaac agacgcagtt gagctgcgta
     8581 agaaagcact cgagctgtca cgcctgatgc gtcatcgtgg cccggactgg tccggtattt
     8641 atgccagcga taacgccatt ctcgctcacg aacgtctgtc aattgttgac gttaacgcgg
     8701 gggcgcaacc tctctacaac caacaaaaaa cccacgtact ggcggtaaac ggtgaaatct
     8761 acaaccacca ggcattgcgc gctgaatatg gcgatcgtta tcagttccag acagggtctg
     8821 actgtgaagt gatcctcgcg ctgtatcagg aaaaagggcc ggaatttctc gacgacttgc
     8881 agggcatgtt tgcctttgcc ctgtacgaca gcgaaaaaga tgcctacctg attggtcgcg
     8941 accatctggg gatcatccca ctgtatatgg gctatgacga acacggtcag ctgtatgtgg
     9001 cctcagaaat gaaatcgctg gtgccagttt gccgcacgat taaagagttc ccggcgggga
     9061 gctatttgtg gagccaggac ggcgaaatcc gttcttatta tcatcgcgac tggttcgact
     9121 ttgatgcagt gaaagataac gtgaccgaca aaaacgagct gcgtcaggct ctggaagatt
     9181 ccgttaaaag ccatctgatg tctgatgtgc cttacggtgt gctgctttct ggtggtctgg
     9241 attcctcaat tatttccgct atcaccaaga aatacgcagc ccgtcgcgtg gaagatcagg
     9301 aacgctctga agcctggtgg ccgcagttac actcctttgc tgtaggtctg ccgggttcac
     9361 cggatcttaa agcagcccag gaagtggcaa accatctggg cacggtgcat cacgaaattc
     9421 acttcactgt acaggaaggt ctggatgcca tccgcgacgt gatttaccac atcgaaactt
     9481 atgatgtgac cactattcgc gcttcaacac cgatgtattt aatgtcgcgt aagatcaagg
     9541 cgatgggcat taaaatggtg ctgtccggtg aaggttctga tgaagtgttt ggcggttatc
     9601 tttacttcca taaagcgccc aacgctaaag aactgcatga agagacggtg cgtaaactgc
     9661 tggccctgca tatgtatgac tgcgcgcgcg ccaacaaagc gatgtccgcc tggggcgtgg
     9721 aagcgcgcgt tccgttcctc gacaaaaaat tccttgatgt ggcgatgcgt attaacccac
     9781 aggataaaat gtgcggtaac ggcaaaatgg aaaaacacat cctgcgtgaa tgttttgagt
     9841 catacctgcc tgcaagcgtg gcctggcggc agaaagagca gttctccgat ggcgtcggtt
     9901 acagttggat cgacaccctg aaagaagtgg cggcgcagca ggtttctgat caacagctgg
     9961 aaactgcccg cttccgcttc ccgtacaaca cgccgacgtc caaagaagcg tatctgtacc
    10021 gggagatctt tgaagaactg ttcccacttc cgagcgccgc tgagtgcgta ccgggcggtc
    10081 cttccgtcgc gtgttcttcc gctaaagcga ttgagtggga tgaggcgttc aagaaaatgg
    10141 acgatccgtc tggtcgtgcg gttggcgttc accagtcggc gtataagtaa gaaatgcgaa
    10201 acagccccgg tgaaatccgg ggctgtttca gttattgagg tgcttgttaa ttctgatatg
    10261 cagtaaggaa atgttccggg tttgccacat cactgtttga caactcatca ctgtaggcca
    10321 gtatttcata gattaatttc ccaccactat tgttgaattc cgaatttcat cctgtacgac
    10381 aaaagaatgg ctgtagggtg gggaaaaaac acaaagtaaa caataattga cgaatatagc
    10441 gccacgctgt tcgcaaccta accaaacagt cactttcgag caattttcct tgaaaaagag
    10501 gttgacgctg caaggctcta tacgcataat gcgccccgca acgccgataa ggtatcgcga
    10561 aaaaaaagat ggctacgtag ctcagttggt tagagcacat cactcataat gatggggtca
    10621 caggttcgaa tcccgtcgta gccaccatct tttttgcggg agtggcgaaa ttggtagacg
    10681 caccagattt aggttctggc gccgcaaggt gtgcgagttc aagtctcgcc tcccgcacca
    10741 ttcaccagaa agcgttgtac ggatggggta tcgccaagcg gtaaggcacc
//
LOCUS       DAPGUL010000141        10707 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.144, whole genome shotgun sequence.
ACCESSION   DAPGUL010000141 DAPGUL010000000
VERSION     DAPGUL010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10707
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.144"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            79..792
                     /locus_tag="RHX21_004030"
     CDS             79..792
                     /locus_tag="RHX21_004030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HDV1989147.1"
                     /translation="MNQRNMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPT
                     EHIYLGQSSGRIGEWISQLPVIGAPCGRYLRSKAAHVHEKPSTPPGNITALVIYLLSC
                     WRAYKFRKMLCKSQQGFLLITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELK
                     LYQWMASYLPVLLIRLGIDEQTAFARKPDHQLAALQEKIAVTPQLTFNGAKILELDGR
                     HPADEILQASLRAIHAALS"
     gene            824..1582
                     /locus_tag="RHX21_004031"
     CDS             824..1582
                     /locus_tag="RHX21_004031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989148.1"
                     /translation="MDALQTQTVNSTTAPQPNYIPGLIAVVGCDGTGKSTLTTDLVKS
                     LQQHWQTERRYLGLLSGEDGDKIKRLPLVGVWLERRLAAKSSKTQSMKTKSPALWAAV
                     IMYCFSLRRMANLRKVQRLAQSGVLVVSDRFPQAEISGFYYDGPGIGVERATGKISMF
                     LAQRERRLYQQMAQYRPELIIRLGIDIETAISRKPDHDYAELQDKIGVMSTIGYNGTK
                     ILEIDSRAPYSEVLEQAQKAVSLVAIVSDRRSLT"
     gene            1628..2977
                     /locus_tag="RHX21_004032"
     CDS             1628..2977
                     /locus_tag="RHX21_004032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HDV1989149.1"
                     /translation="MAGFNIKHWFADGAFRTIIRNSAWLGSSNVVSALLGLLALSCAG
                     KGMTPAMFGVLVIVQSYAKSISDFIKFQTWQLVVQYGTPALTNNNPQQFRNVVSFSFS
                     LDIVSGAVAIVGGIALLPFLSHSLGLDDQSFWLAALYCTLIPSMASSTPTGILRAVDR
                     FDLIAVQQATKPFLRAAGSVVAWYFDFGFAGFVIAWYVSNLVGGTMYWWFAARELRRR
                     NIHNAFKLNLFESARHIKGAWSFVWSTNIAHSIWSARNSCSTVLVGIVLGPAAAGLFK
                     IAMTFFDAAGTPAGLLGKSFYPEVMRLDPRTTRPWLLGVKSGLLAGGIGILVALAVFI
                     VGKPLISLVFGVKYLEAYDLIQVMLGAIVISMLGFPQESLLLMAGKQRAFLVAQTIAS
                     IGYIVLLFMFCHLFGVLGAAFAYFGGQCLDVALSLIPTLKAFFQRHSLLYNAAGEKS"
     gene            2977..3801
                     /locus_tag="RHX21_004033"
     CDS             2977..3801
                     /locus_tag="RHX21_004033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989150.1"
                     /translation="MMRKYFPLEASERLFVAIEEDDVVDAQVSLPPTIALSCTTEIIH
                     DNYALCLQFWLNGVDRQELLRLVRKQAKGDELTADERKQFKYMRARYKHLRFAQRLYL
                     KKHQAGFLFGKTTVFLGRFQDGFRNGKKNIVSYYGNLLRIYLSSPVWSLVNYSLRHSQ
                     LESVSSFIAYRQKQMHTLKEIIAKPRLTGREFHDVRKIISQQVSYYDTLRSLDPENKE
                     ALQISRFLAAINGLMGDKHDDMVADDMENRQSYDAPLALDSDIRQRLELLISRFPL"
     gene            3813..4373
                     /locus_tag="RHX21_004034"
     CDS             3813..4373
                     /locus_tag="RHX21_004034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708799.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtfJ family protein"
                     /protein_id="HDV1989151.1"
                     /translation="MSSRLIIALIIMLLAPGVQAHNFVTGKTVTPVYIQEGGELLLNS
                     DDEIHYQKWKSTQLAGKVRIIQYIAGRKSAKKKNSLLIKAVEAANFPQDRFQPTTIVN
                     TDDAIFGTGYFVVGKIEKNKRRYPWAQFVIDGNGQGRVAWRLPEQSSTILVLNKAGQI
                     QWAKDGSLTPEEVDHVIALAQKLINE"
     gene            4404..5474
                     /gene="lptF"
                     /locus_tag="RHX21_004035"
     CDS             4404..5474
                     /gene="lptF"
                     /locus_tag="RHX21_004035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptF"
                     /protein_id="HDV1989152.1"
                     /translation="MKLVEHYIMRGTRRLVLIIVGFLIFIFASYSAQRYLTEAANGTL
                     ALDVVLDIVFYKVLIALEMLLPVGLYVSVGVTLGQMYTDSEITAISAAGGSPGRLYKA
                     VLYLAIPLSIFVTLLSMYGRPWAYAQIYQLEQQSQSELDVRQLRAKKFNTNDNGRMIL
                     SQTVDQDNNRLTDALIYTSTANRTRIFRARSVDVVDPSPEKPTVMLHNGTAYLLDHQG
                     RDDNEQIYRNLQLHLNPLDQSPNVKRKAKSVTELARSAFPADHAELQWRQSRGLTALL
                     MALLAISLSRVKPRQGRFSTLLPLTLLFIAIFYGGDVCRTLVANGAIPLIPGLWLVPG
                     LMLMGLLMLVARDFSLLQKFSR"
     gene            5471..6550
                     /gene="lptG"
                     /locus_tag="RHX21_004036"
     CDS             5471..6550
                     /gene="lptG"
                     /locus_tag="RHX21_004036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptG"
                     /protein_id="HDV1989153.1"
                     /translation="MNVFSRYLIRHLFLGFAAAAGLLLPLFTTFNLINELDDVSPGGY
                     RWTQAVLVVLMTLPRTLVELSPFIALLGGIVGLGQLSKNSELTAIRSTGFSIFRIALV
                     ALVAGILWTVSLGAIDEWVASPLQQQALQIKSTATALGEDDDITGNMLWARRGNEFVT
                     VKSLNEQGQPVGVEIFHYRDDLSLESYIYARSATIEDDKTWILHGVNHKKWLNGKETL
                     EILDNLAWQSTFTSMNLEELSMPGNSFSVRQLNHYINYLQETGQPSSEYRLALWEKLG
                     HPILTLAMILLAVPFTFSAPRSPGMGSRLAVGVIVGLLTWISYQIMVNLGLLFALSAP
                     VAALGLPMAFVLAALILVYLFDRQH"
     gene            complement(6585..7757)
                     /locus_tag="RHX21_004037"
     CDS             complement(6585..7757)
                     /locus_tag="RHX21_004037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDV1989154.1"
                     /translation="MGLYDKYARLAGERLQFSDNGLTPFGTCIDEVYSATEGRIGNKK
                     VILAGTNNYLGLTFNHDAISEGQAALAAQGTGTTGSRMANGSYAPHLALEKEIAEFFN
                     RPTAIVFSTGYTANLGVISALADHNAVVLLDADSHASIYDACSLGGAEIIRFRHNDAK
                     DLERRMVRLGERAKEAIIIVEGIYSMLGDVAPLAEIVDIKRRLGGYLIVDEAHSFGVL
                     GATGRGLAEAVGVEDDVDIIVGTFSKSLASIGGFAVGSEAMEVLRYGSRPYIFTASPS
                     PSCIATVRSSLRTIATQPELRQKLMDNANHLYDGLQKLGYELSSHISPVVPVIIGSKE
                     EGLRIWRELISLGVYVNLILPPAAPAGITLLRCSVNAAHSREQIDAIIQAFATLKQ"
     gene            complement(7757..8005)
                     /locus_tag="RHX21_004038"
     CDS             complement(7757..8005)
                     /locus_tag="RHX21_004038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDV1989155.1"
                     /translation="MVNREIVMDYILSCLQDLVENGVEIKPDSDLVNDLGLESIKVMD
                     LLMMLEDRFDISIPINILLDVKTPAQLMETLLPWLENK"
     gene            complement(8037..8951)
                     /locus_tag="RHX21_004039"
     CDS             complement(8037..8951)
                     /locus_tag="RHX21_004039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001481799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HDV1989156.1"
                     /translation="MNQTVAVTGATGFIGKYIIDNLLARGFHVRALTRTARAHVNDNL
                     TWVRGSLEDTHSLSKLVAGASAVVHCAGQVRGHKEEIFTRCNVDGSLRLMQAAKESCF
                     CQRFLFISSLAARHPELSWYANSKHIAEQRLTAMADEITLGVFRPTAVYGPGDKELKP
                     LFDWMLRGLLPRLGAPDTQLSFLHVTDFAQAVGQWLSAETVQTQTYELCDGVAGGYDW
                     QRIQQLAANVRCGSVRMVGIPLPVLTCLADISTALSRLAGKEPMLTRSKIRELTHADW
                     SASNNRISEDINWFPGISLEHALRNGLF"
     gene            complement(8948..10678)
                     /locus_tag="RHX21_004040"
     CDS             complement(8948..10678)
                     /locus_tag="RHX21_004040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acyl-AMP ligase"
                     /protein_id="HDV1989157.1"
                     /translation="MVYMSNKIFTHSLPMRYADFPTLVDALDYAALSSAGMNFYDRRC
                     QLEDQLEYQTLKTRAEAGAKRLLSLNLKKGERVALIAETSSGFVEAFFACQYAGLVAV
                     PLAIPMGVGQRDSWSAKLQGLLASCQPAAIITGDEWLPLVNAATHNNPELHVLSHAWF
                     KALPEADVALQRPVPNDIAYLQYTSGSTRFPRGVIITHREVMANLRAISHDGIKLRPG
                     DRCVSWLPFYHDMGLVGFLLTPVATQLSVDYLRTQDFAMRPLQWLKLISKNRGTVSVA
                     PPFGYELCQRRVNEKDLAELDLSCWRVAGIGAEPISAEQLHQFAECFRQVNFDDKTFM
                     PCYGLAENALAVSFSDEGSGVVVNEVDRDILEYQGKAVAPGAETRAVSTFVNCGKALP
                     EHGIEIRNEAGMPVAERVVGHICISGPSLMSGYFGDQVSQDEIAATGWLDTGDLGYLL
                     DGYLYVTGRIKDLIIIRGRNIWPQDIEYIAEQEPEIHSGDAIAFVTAQEKIILQIQCR
                     ISDEERRGQLIHALAARIQSEFGVTAAIDLLPPHSIPRTSSGKPARAEAKKRYQKAYA
                     ASLHVQESLA"
BASE COUNT         2577 a         2670 c         2798 g         2662 t
ORIGIN      
        1 ttgtcacaat aaggttgaac ggatattctg agcacggacc acgtaatatt caatacatta
       61 tttactgccg ggtttttcgt gaatcaacgt aatatgtcaa taattaattc cacgccagtg
      121 cgtgttattg ccattgtagg atgtgatggt tcaggtaaat cgaccctcac ggcaagcctg
      181 gtaaatgaac tggcagcaag aatgccaaca gaacacattt atctcgggca atcgtccggg
      241 cgaattggcg aatggatttc acagctccct gttattggcg caccttgtgg gcgttatctg
      301 cgaagtaaag cggcacatgt gcacgaaaaa ccctcaacac cgcctggcaa tattactgcg
      361 ctggttatct atctgctttc ctgctggcgg gcgtacaagt ttcgcaaaat gttgtgtaaa
      421 agccagcaag gctttctgct catcaccgac cgctacccgc aggttgaagt gccgggtttt
      481 cgctttgatg gcccgcaatt ggcaaaaacc acgggcggta acggttggat aaaaatgtta
      541 aggcagcgcg agctgaagct gtaccaatgg atggcatctt atttgcccgt attgttgatt
      601 cgtcttggca ttgatgaaca aaccgcgttt gcgcgtaaac ctgaccacca actggcagcg
      661 ttacaggaaa aaatcgccgt tacgccgcaa ctgacattca atggcgcaaa gatccttgaa
      721 ctggatgggc gacaccccgc cgatgaaatt ctgcaagcgt cactacgcgc aattcacgcc
      781 gcgctttcct gatcaccaaa atggataggg gatgatttaa cgaatggatg cactacaaac
      841 tcaaactgtt aatagtacaa ccgcgccgca gcccaactac attccggggc tgattgcggt
      901 ggtcgggtgt gatggcaccg gtaaatccac actgaccacc gacctggtga aatcgctgca
      961 acaacactgg caaaccgagc ggcgctatct ggggctgctc tccggcgaag acggcgacaa
     1021 aatcaaacga ttgccgttgg ttggcgtctg gctggaacgg cgactggcgg ccaaatcctc
     1081 gaaaacccaa agcatgaaaa ccaaatctcc ggcgctatgg gcggcggtga ttatgtactg
     1141 cttctcgctg cgaagaatgg cgaatctacg caaggttcag cgactggcgc aaagtggcgt
     1201 tctggtggtc agcgatcgct tcccgcaggc tgaaatttcg ggcttttatt atgatggacc
     1261 ggggattggc gtcgaacgtg cgaccgggaa aatcagcatg tttctggcgc agcgcgaacg
     1321 gcgtttatac caacaaatgg cgcaatatcg cccggaatta attattcgcc tgggcattga
     1381 tattgagact gccatctccc gcaagcctga ccatgactat gccgagctgc aggacaaaat
     1441 cggcgtcatg tcgacgattg gctataacgg cacaaaaatt cttgagattg attccagagc
     1501 gccctacagc gaagtgctgg aacaggcaca gaaggcggtt tctctggttg ccatcgtttc
     1561 tgaccgccga agtttaactt aaggctggcg ggatactttt tactatcaac gataaggtca
     1621 ggctgaattg gcgggtttta acatcaaaca ttggtttgca gatggcgcgt ttcgcaccat
     1681 tattcgcaat agcgcctggt taggctccag taatgtcgtg agcgccttgc tgggtctgtt
     1741 ggcgctctcg tgtgccggta aagggatgac gcccgccatg tttggcgtac tggtgattgt
     1801 gcaatcgtac gccaagtcga tcagcgattt tattaagttt cagacatggc aactggtggt
     1861 tcagtacgga acgccagcct tgaccaacaa taatccgcag caatttcgca atgtcgtctc
     1921 attttccttc tcgctggata tcgtcagcgg cgcggtggcg attgtcggcg gcattgcctt
     1981 actgccattc ctttcccatt cattaggtct ggatgaccaa agcttttggc tggcggcgct
     2041 gtattgcacg ctcattcctt caatggcttc ctccacgccg accggcattc tgcgtgcggt
     2101 agatcgcttc gatttaattg ctgtacagca ggcgacgaaa ccttttctgc gcgcagcggg
     2161 gagcgtcgta gcctggtatt ttgactttgg ttttgcgggt tttgttattg cctggtacgt
     2221 gtcgaatctg gttggcggca ccatgtactg gtggtttgca gcgcgcgaat tacgccgcag
     2281 aaatatccat aatgccttca aattgaatct gtttgagtct gcccgacaca tcaaaggcgc
     2341 gtggagtttt gtctggtcaa ccaacattgc ccactccatc tggtcggcgc gtaactcgtg
     2401 cagcacagtg ctggtgggga tcgtgttagg acccgctgcc gccgggttat ttaaaatcgc
     2461 catgacattc ttcgacgccg ccggaacgcc agcgggtttg ctgggtaaaa gtttttaccc
     2521 agaggtgatg cgtttagatc cgcgcaccac cagaccgtgg ttgttaggtg tgaagtccgg
     2581 tttactggcg ggcggaatcg gtattctggt ggcgctcgcg gtgtttatcg tcggcaagcc
     2641 gctcatttcg ctggtgtttg gcgttaagta tctcgaagcg tatgacctga ttcaggtgat
     2701 gctgggcgca attgtgattt cgatgctggg cttccctcag gagtcattgc tattgatggc
     2761 gggaaaacag cgcgcttttc tcgtggcgca aaccatcgcc tcaatcggct acatcgtatt
     2821 gctgttcatg ttctgtcatc tgtttggtgt gctgggagca gcgtttgctt acttcggtgg
     2881 gcaatgtctg gacgtggcgc tctcgttaat tccaacctta aaggcatttt ttcagcgcca
     2941 ttccttgctt tataacgcag ccggagagaa atcctgatga tgagaaaata tttcccgctt
     3001 gaggcgagcg agcgtctatt tgttgcgatt gaagaagatg atgtcgttga tgcacaggtt
     3061 agtttgccgc cgactattgc actaagttgt accaccgaaa tcattcatga taattacgcg
     3121 ttatgcctgc aattctggct caatggcgtt gatcgtcagg aattactgcg tttagttcgc
     3181 aaacaagcca aaggcgatga gctgactgct gatgagcgca aacaatttaa atacatgcga
     3241 gcgcgctaca agcacctgcg ttttgcgcaa cggctgtatt taaagaagca tcaggccgga
     3301 tttttattcg gcaaaacgac cgtttttctg gggcgttttc aggacggctt tcgtaacggt
     3361 aagaaaaata ttgtgtcgta ttacggcaac ctgttacgga tttatttaag ctctccggtc
     3421 tggtcgttgg tgaactattc attacgccat agccagttag aaagcgtaag cagttttatt
     3481 gcctatcggc aaaagcaaat gcataccctg aaagagatta ttgccaaacc gcgactaacc
     3541 ggcagggaat ttcatgatgt gcgaaaaatc atcagccaac aggtttctta ttacgacacc
     3601 ttaagatcgc ttgatcctga aaataaagag gcgttacaga tttcccgttt cctcgccgcc
     3661 attaatggcc tgatgggaga taaacacgac gacatggtgg cggatgatat ggaaaaccgc
     3721 cagtcgtatg atgcaccgtt ggcgctggat agcgatattc gtcagcgctt agagctgctg
     3781 atttcgcgtt ttccgctata gccggagcaa tgatgtcatc tcgtttgatt attgcgttga
     3841 ttatcatgct cttagccccg ggtgtgcagg cacacaattt cgtcactggc aaaacggtta
     3901 cccctgttta tatccaggaa ggcggcgagc tgcttctgaa tagcgacgac gaaattcact
     3961 accaaaagtg gaaaagcaca caattagcgg gaaaagtccg cattattcag tatatcgccg
     4021 ggcgtaagtc ggcgaagaaa aagaactcac tgttaattaa agcggttgaa gcggcaaact
     4081 ttccgcagga tcgttttcag cccaccacca ttgtgaacac cgatgatgcc atctttggta
     4141 ccggctattt tgtcgttggc aaaatcgaaa aaaataaacg ccgctatccg tgggcgcaat
     4201 tcgttattga cggcaatgga cagggacgcg ttgcctggcg cttgccggag cagagttcaa
     4261 ccattctggt gctgaataaa gccgggcaaa ttcagtgggc aaaggacggc agcctgacgc
     4321 cggaagaggt agatcatgtc attgcgttgg cgcagaaact gatcaatgaa taaaaaactc
     4381 aaaggattga gggcgttagt tagatgaagc tggttgaaca ctacatcatg cgtggtacgc
     4441 gccgtctggt gctgattatc gtcggttttc tgatctttat tttcgccagc tactccgcac
     4501 agcgttatct gaccgaagcg gcaaatggga cattagctct tgatgttgtg ctggatatcg
     4561 ttttctacaa agtactgatt gcactggaga tgttgttacc tgttggtctg tatgtgtcag
     4621 ttggcgtgac gctagggcag atgtataccg actcggaaat taccgctatc tctgcggcgg
     4681 ggggcagtcc gggacgcttg tacaaagccg ttctttatct ggcgataccg ctaagtattt
     4741 ttgtcaccct tctgtcgatg tatggtcgtc cgtgggctta tgcgcagatt tatcaactgg
     4801 agcagcagtc gcagtcggag ctggatgttc gccagttgcg ggcaaagaaa tttaacacta
     4861 acgataacgg acgaatgatc ctttcgcaga cggttgatca ggataataat cgcctgactg
     4921 acgcgctgat ttatacttct actgccaatc gaacccgtat tttccgcgcc cgttcggttg
     4981 atgtggttga cccatcaccc gagaaaccga ccgttatgtt gcacaacggc actgcctatc
     5041 ttctcgatca tcaggggcgt gacgacaacg aacagatcta ccgtaatctg caattacatc
     5101 tgaatccgct ggatcaaagc cctaacgtca aacgcaaagc aaaatcggtc acggagctgg
     5161 cgcgctccgc ctttcctgcc gatcatgccg aactgcaatg gcgacaaagc cgtggcctga
     5221 ccgcattgtt gatggcgctg ctggccattt cattaagtcg ggtaaaaccg cggcaagggc
     5281 gattttcaac gttattgcca ctgacgttgc tgtttattgc cattttttat ggcggcgacg
     5341 tctgccgtac gctggtggct aacggcgcga ttcccctcat tcctggtttg tggttagtac
     5401 ccggactcat gctaatgggc ctgctgatgc tggtcgcacg cgacttctct ttgctgcaga
     5461 aattttcccg atgaatgttt tcagtcgcta tttaatccgt catctctttc tcggttttgc
     5521 cgccgccgca gggctattgc tgccgctttt taccaccttc aacctgatta acgaactgga
     5581 tgatgtcagc ccgggcggtt atcgctggac tcaggcggtg ctggtggtgc taatgacctt
     5641 accgcgcaca ctggtcgaac tttcgccgtt tatcgcgtta ttgggtggta ttgttggact
     5701 ggggcagtta tcgaaaaaca gtgagcttac cgccattcgc agcacggggt tttctatctt
     5761 ccgtattgca ctggtggcgc tggttgccgg gatattgtgg actgtttcgt taggcgcgat
     5821 agatgagtgg gtggcgtcgc cattgcagca acaggcgttg caaatcaaat cgaccgccac
     5881 cgcgttgggg gaggacgatg atattaccgg caatatgctg tgggccaggc gcggtaatga
     5941 atttgtgacg gtgaaatcgc tgaatgaaca gggccagcct gtgggcgtgg agatatttca
     6001 ttatcgcgac gatctctcgc tcgaatccta catttatgca cgcagtgcca ccattgaaga
     6061 cgacaaaacg tggattctgc atggtgtgaa tcataaaaaa tggctgaatg gcaaagaaac
     6121 gctggaaata ttagataatc ttgcctggca atcgacattc accagtatga atcttgaaga
     6181 actgtcgatg ccgggcaata gcttttccgt tcgtcagctc aaccattaca tcaattactt
     6241 gcaggaaacc ggacaaccga gcagtgagta tcgcctggca ttgtgggaaa agctggggca
     6301 tcccatttta accctggcga tgattttgct ggcagtgcct tttaccttta gcgccccgcg
     6361 ctcgccgggg atgggcagcc gtcttgctgt aggcgtcatc gttggcttac ttacctggat
     6421 aagctaccaa ataatggtca atctgggatt attatttgcg ctgagtgcgc ccgttgctgc
     6481 actcggttta cctatggcat ttgtgctggc ggcgttgatt ctggtgtatc tatttgatag
     6541 gcaacattaa acccgccgtg gcgcaacacc acggcgggct cacattactg cttcagagta
     6601 gcaaatgcct gaatgatggc atcgatttgc tcacgactgt gggcagcatt tacgctacag
     6661 cgcagcagcg tgatgcctgc aggcgcggca ggcggcagga taagattcac atacacgccc
     6721 agcgagataa gctcgcgcca gatgcgtaaa ccttcctctt tcgaaccgat tattactggc
     6781 actaccgggc taatatgtga acttaactca taacccagtt tttgcagacc gtcatacaga
     6841 tggttggcgt tatccatcag cttttgccgc agctctggtt gtgtggcaat agttcttaac
     6901 gacgagcgca cggtcgcaat gcaggacgga gaaggagagg cggtaaaaat atacgggcgg
     6961 ctgccgtagc gcagcacttc catcgcttcc gaaccgacag caaaaccgcc aatcgaggcc
     7021 agacttttac tgaaagtacc aacgataata tccacatcat cttcaacgcc gacagcttca
     7081 gccagtccgc gccccgttgc gcctaacacg ccaaacgaat gcgcttcatc gacaatcaaa
     7141 taaccaccga gacgacgttt gatatcaaca atttccgcca gcggcgcaac gtcaccgagc
     7201 atgctgtaga tgccctcaac gatgataatc gcctctttcg cccgttcacc gaggcgaacc
     7261 atgcgccgtt ccagatcttt agcatcgtta tggcggaaac gaataatttc cgcgccaccg
     7321 agagaacagg cgtcataaat actggcgtgg ctgtcggcat ccagtaacac cacggcgtta
     7381 tggtcggcaa gtgcgctgat gacgcctaaa ttagcggtat aaccggttga aaaaacgata
     7441 gcggtagggc gattgaaaaa ctcggcaatc tctttctcta acgccaggtg cggcgcataa
     7501 ctgccgtttg ccatacgaga accggtggtg ccggtacctt gggccgctaa cgcggcctga
     7561 ccttcgctga tggcatcatg attaaaggtt aaaccgagat aattattggt cccggccaga
     7621 atcacttttt tattgccgat ccggccttcg gtggcggaat acacttcatc aatacaggtg
     7681 ccaaacggtg ttaacccgtt gtcactaaat tgcagtcgct cgccagcaag gcgcgcatat
     7741 ttatcgtata gccccattat ttattctcca gccatggaag tagagtttcc attaattgcg
     7801 caggggtttt gacatccagc agaatattaa taggaatgga aatatcgaat ctgtcttcca
     7861 gcatcattaa gagatccatc actttgatcg actccaggcc aagatcgttg acgagatcgc
     7921 tgtcgggctt aatttccaca ccgttttcga ccaaatcctg taaacaggaa aggatgtaat
     7981 ccattactat ttcacgattt accatagaaa cgttaacaca cctttaaaca agacaatcaa
     8041 aatagcccgt tgcgtaatgc gtgttccagg ctaatcccgg gaaaccaatt aatatcttca
     8101 gaaatacggt tattacttgc cgaccagtcg gcgtgggtta attcacgaat tttcgagcgg
     8161 gtcagcatag gttctttacc tgccaggcga ctcaacgcgg tactgatatc cgcaaggcag
     8221 gtgagtaccg gcagaggaat accaaccatt cgcacggaac cgcaacggac gttggcggca
     8281 agttgctgta tgcgttgcca gtcatagccg ccagcgacgc catcgcataa ttcataggtt
     8341 tgcgtctgta cagtttcggc gcttaaccac tgacccactg cttgcgcaaa atcggtgacg
     8401 tgcaggaaag agagctgtgt atctggtgca ccaagtcgtg gcagcaggcc gcgcagcatc
     8461 cagtcaaaca gcggttttaa ctctttatcg ccgggaccat acacggctgt cgggcgaaaa
     8521 acgcccagcg taatttcgtc agccattgca gtcagccgtt gttcggcgat gtgtttggaa
     8581 tttgcgtacc aggagagctc gggatggcgc gccgccagcg aagagataaa cagaaaacgt
     8641 tggcaaaagc agctctcttt tgctgcttgc atcaggcgca ggctgccgtc aacgttacag
     8701 cgggtgaaaa tctcttcttt gtgcccgcgc acttgcccgg cgcaatggac cactgcgctg
     8761 gctccggcaa ccagcttgct aagtgaatga gtatcttcca gcgaaccgcg cacccaggtg
     8821 agattatcat tgacgtgagc gcgggcagta cgcgtcaatg cgcgaacgtg aaagccgcgg
     8881 gcgagcaggt tatcgataat atatttaccg ataaacccgg tagcgcccgt caccgcgaca
     8941 gtttgattca tgccagggat tcctgcacat gaaggcttgc agcataagcc ttctgataac
     9001 gttttttcgc ttccgcacgg gcaggcttgc cggaggatgt tcggggaata ctgtggggcg
     9061 gcaacagatc gatagccgct gttacgccaa attcgctttg gatccgtgct gccagcgcgt
     9121 ggataagctg cccgcgacgt tcttcgtcgc tgatccgaca ctggatctgc aaaatgattt
     9181 tttcctgggc ggtaacaaaa gcaatcgcat cgccagaatg aatttccggt tcttgttccg
     9241 caatatattc aatatcctgc ggccagatat tacggccacg aataataatc agatctttaa
     9301 tacgtccggt gacatacaga taaccgtcca gcagataacc gaggtcgccg gtgtctaacc
     9361 agcccgtcgc ggcaatctcg tcttgcgaaa cctggtcgcc aaagtaaccg ctcatcaggc
     9421 tggggccgga gatgcaaata tggcctacca cacgttccgc gaccggcata cctgcttcat
     9481 tgcggatttc aatgccatgt tccggcaacg ctttgccgca gttgacgaaa gtcgatacgg
     9541 cgcgtgtttc agcacccggc gcgacggctt tgccctgata ttctaggatg tcgcgatcca
     9601 cttcgttaac cacaacccca gagccttcat cagagaagct gacagccagc gcattttctg
     9661 ccagtccgta gcacggcatg aacgttttat cgtcaaagtt aacctgacgg aaacattcag
     9721 cgaattgatg gagttgttct gcggagatcg gctcagcacc aataccagcg acgcgccagc
     9781 aggaaagatc cagttcagcg agatcttttt cattcacgcg gcgttggcac aattcatagc
     9841 caaacggcgg cgcaacggaa acggtgccgc gatttttact gatcaattta agccattgca
     9901 aaggacgcat ggcaaaatcc tgagtgcgca aataatctac tgaaagttgc gtggcgacgg
     9961 gggtcaggag aaagccgacc agtcccatat catggtagaa aggcagccag gagacgcagc
    10021 ggtcgccagg gcgtaattta atgccatcgt ggcttatagc acgtagatta gccatcactt
    10081 cgcgatgggt gataatgacg ccacggggaa aacgggtgct gccggaggtg tactggaggt
    10141 aggcgatatc gttcggaact ggacgctgga gcgcaacatc ggcttccggt aatgccttaa
    10201 accaggcgtg gcttaaaaca tgtaattcgg ggttgttatg cgtcgcggca ttgaccagtg
    10261 gcaaccactc atcaccagtg ataatggctg cgggctggca acttgccagt aaaccctgga
    10321 gtttggcgct ccaggaatcc cgctgaccga cgcccattgg aatcgccaac gggacggcga
    10381 ctaagccagc atactgacag gcaaaaaaag cctctacaaa cccgctactc gtttcggcaa
    10441 tcagcgccac gcgttcgcct tttttcaggt tcagcgataa caaccgcttc gcaccagctt
    10501 cggcacgcgt ttttaacgtc tgatattcca gttgatcttc aagttggcaa cgtctgtcat
    10561 aaaaattcat tccggcgcta ctcagagcgg cgtagtccaa agcatcaacc agcgttggaa
    10621 aatcggcata gcgcataggt agggaatgcg taaagatttt attagacata tacaccacga
    10681 aaaaattgga tatcaaaaat aaaatga
//
LOCUS       DAPGUL010000142        10703 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.145, whole genome shotgun sequence.
ACCESSION   DAPGUL010000142 DAPGUL010000000
VERSION     DAPGUL010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10703
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.145"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            34..1176
                     /locus_tag="RHX21_004041"
     CDS             34..1176
                     /locus_tag="RHX21_004041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001327865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDV1989158.1"
                     /translation="MECDLLMIKIEKVINKNDLKAFIAFPSSLYPDDPNWIPPLFIER
                     NEHLSAKNPGTDHIIWQAWVAKKAGQIVGRITAQIDTLHRERYGEDTGHFGMIDAIDD
                     PQVFAALFGAAEAWLKSQGASKISGPFSLNINQESGLLIEGFDTPPCAMMPHGKPWYA
                     AHIEQLGYHKGIDLLAWWMQRTDLTFSPALKKLMDQVRKKVTIRCINRQRFAEEMQIL
                     REIFNSGWQHNWGFVPFTEHEFATMGDQLKYLVPDDMIYIAEIDSAPCAFIVGLPNIN
                     EAIADLNGSLFPFGWAKLLWRLKVSGVRTARVPLMGVRDEYQFSRIGPVIALLLIEAL
                     RDPFARRKIDALEMSWILETNTGMNNMLERIGAEPYKRYRLYEKQI"
     gene            complement(1183..1947)
                     /gene="glcC"
                     /locus_tag="RHX21_004042"
     CDS             complement(1183..1947)
                     /gene="glcC"
                     /locus_tag="RHX21_004042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GlcC"
                     /protein_id="HDV1989159.1"
                     /translation="MKDERRPICEVVAESIERLIIDGVLKVGQPLPSERRLCEKLGFS
                     RSALREGLTVLRGRGIIETAQGRDSRVARLNRVQDTSPLIHLFSTQPRTLYDLLDVRA
                     LLEGESARLAATLGTQADFVVITRCYEKMLAASENNKEISLIEHAQLDHAFHLAICQA
                     SHNQVLVFTLQSLTDLMFNSVFASVNNLYHRPQQKKQIDRQHARIYNAVLQRLPHVAQ
                     RAARDHVRTVKKNLHDIELEGHHLIRSAVPLEMNLS"
     gene            2198..3697
                     /gene="glcD"
                     /locus_tag="RHX21_004043"
     CDS             2198..3697
                     /gene="glcD"
                     /locus_tag="RHX21_004043"
                     /EC_number="1.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase subunit GlcD"
                     /protein_id="HDV1989160.1"
                     /translation="MSILYEERLDGALPDVDRTSVLMALREHVPGLEILHTDEEIIPY
                     ECDGLSAYRTRPLLVVLPKQMEQVTAILAVCHRLRVPVVTRGAGTGLSGGALPLEKGV
                     LLVMARFKEILDINPVGRRARVQPGVRNLAISQAVAPHNLYYAPDPSSQIACSIGGNV
                     AENAGGVHCLKYGLTVHNLLKIEVQTLDGEALTLGSDALDSPGFDLLALFTGSEGMLG
                     VTTEVTVKLLPKPPVARVLLASFDSVEKAGLAVGDIIANGIIPGGLEMMDNLSIRAAE
                     DFIHAGYPVDAEAILLCELDGVESDVQEDCERVNDILLKAGATDVRLAQDEAERVRFW
                     AGRKNAFPAVGRISPDYYCMDGTIPRRALPGVLEGIARLSQQYDLRVANVFHAGDGNM
                     HPLILFDANEPGEFARAEELGGKILELCVEVGGSISGEHGIGREKINQMCAQFNSDEI
                     TTFHAVKAAFDPDGLLNPGKNIPTLHRCAEFGAMHVHHGHLPFPELERF"
     gene            3697..4749
                     /gene="glcE"
                     /locus_tag="RHX21_004044"
     CDS             3697..4749
                     /gene="glcE"
                     /locus_tag="RHX21_004044"
                     /EC_number="1.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase subunit GlcE"
                     /protein_id="HDV1989161.1"
                     /translation="MLRECDYSQALLEQVNQAISDKTPLVIQGSNSKAFLGRPVTGQT
                     LDVRCHRGIVNYDPTELVITARAGTPLVAIEAALESAGQMLPCEPPHYGEEATWGGMV
                     ACGLAGPRRPWSGSVRDFVLGTRIITGAGKHLRFGGEVMKNVAGYDLSRLMAGSYGCL
                     GVLTEISMKVLPRPRASLSLRREISLQEAMNEIAQWQLQPLPISGLCYFDNALWIRLE
                     GGEGSVKAARELLGGEEVAGQFWQQLREQQLPFFSLPGTLWRISLPSDAPMMDLPGEQ
                     LIDWGGALRWLKSTAEDNQIHRIARNAGGHATRFSAGDGGFAPLSAPLFRYHQQLKQQ
                     LDPCGVFNPGRMYAEL"
     gene            4760..5983
                     /gene="glcF"
                     /locus_tag="RHX21_004045"
     CDS             4760..5983
                     /gene="glcF"
                     /locus_tag="RHX21_004045"
                     /EC_number="1.1.99.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate oxidase subunit GlcF"
                     /protein_id="HDV1989162.1"
                     /translation="MQTQLTEEMRQNARALEADSILRACVHCGFCTATCPTYQLLGDE
                     LDGPRGRIYLIKQVLEGNEVTLKTQEHLDRCLTCRNCETTCPSGVRYHNLLDIGRDIV
                     EQKVKRPLPERMLREGLRQVVPRPAVFRALTQVGLVLRPFLPEQVRAKLPAETVKAKP
                     RPPLRHKRRVLMLEGCAQPTLSPNTNAATARVLDRLGISVMSANEAGCCGAVDYHLNA
                     QEKGLERARNNIDAWWPAIEAGAEAILQTASGCGAFVKEYGQMLKNDALYADKARQVS
                     ELAVDLVELLREEPLEKLAVRGDKKLAFHCPCTLQHAQKLNGEVEKVLLRLGFTLTDV
                     PDSHLCCGSAGTYALTHPDLARQLRDNKMNALESGKPEMIVTANIGCQTHLASAGRTS
                     VRHWIEIVEQALEKE"
     gene            5988..6392
                     /locus_tag="RHX21_004046"
     CDS             5988..6392
                     /locus_tag="RHX21_004046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein GlcG"
                     /protein_id="HDV1989163.1"
                     /translation="MKTKVILSQQMASAIIAAGQEEAQKNNWSVSIAVADDGGHLLAL
                     SRMDDCAPIAAYISQEKARTAALGRRETKGYEEMVNNGRTAFVTAPLLTSLEGGVPVV
                     VDGQIIGAVGVSGLTGAQDAQVAKAAAAVLAK"
     gene            6414..8585
                     /gene="glcB"
                     /locus_tag="RHX21_004047"
     CDS             6414..8585
                     /gene="glcB"
                     /locus_tag="RHX21_004047"
                     /EC_number="2.3.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate synthase G"
                     /protein_id="HDV1989164.1"
                     /translation="MSQTITQGRLRIDANFKRFVDEEVLPGTGLDAAAFWRNFDEIVH
                     DLAPENRQLLAERDRIQAALDEWHRSNPGPVKDKAAYKSFLRELGYLVPQLERVTVET
                     TGIDSEITSQAGPQLVVPAMNARYALNAANARWGSLYDALYGSDIIPQEGAMVSGYDP
                     QRGEQVIAWVRRFLDESLPLENGSYQDVVAFKVVDKQLRIQLKNGKETTLRTPAQFVG
                     YRGDAAALTCILLKNNGLHIELQIDANGRIGKDDPAHINDVIVEAAISTILDCEDSVA
                     AVDAEDKILLYRNLLGLMQGTLQEKMEKNGRQIVRKLNDDRHYTAADGSEISLHGRSL
                     LFIRNVGHLMTIPVIWDSEGNEIPEGILDGVMTGAIALYDLKVQKNSRTGSVYIVKPK
                     MHGPQEVAFANKLFTRIETMLGMAPNTLKMGIMDEERRTSLNLRSCIAQARNRVAFIN
                     TGFLDRTGDEMHSVMEAGPMLRKNQMKSTPWIKAYERNNVLSGLFCGLRGKAQIGKGM
                     WAMPDLMADMYSQKGDQLRAGANTAWVPSPTAATLHALHYHQTNVQSVQANIAQTEFN
                     AEFEPLLDDLLTIPVAENANWSVEEIQQELDNNVQGILGYVVRWVEQGIGCSKVPDIH
                     NVALMEDRATLRISSQHIANWLRHGILTKEQVQASLENMAKVVDQQNAGDPAYRPMAG
                     NFANSCAFKAASDLIFLGVKQPNGYTEPLLHAWRLREKESH"
     gene            8941..10623
                     /gene="glcA"
                     /locus_tag="RHX21_004048"
     CDS             8941..10623
                     /gene="glcA"
                     /locus_tag="RHX21_004048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycolate permease GlcA"
                     /protein_id="HDV1989165.1"
                     /translation="MVTWTQMYMPMGGLGLSALVALIPIIFFFVALAVLRLKGHVAGA
                     ITLILSILIAIFAFKMPIDMAFAAAGYGFIYGLWPIAWIIVAAVFLYKLTVASGQFDI
                     IRSSVISITDDQRLQVLLIGFSFGALLEGAAGFGAPVAITGALLVGLGFKPLYAAGLC
                     LIANTAPVAFGALGVPILVAGQVTGIDPFHIGAMAGRQLPFLSVLVPFWLVAMMDGWK
                     GVKETWPAALVAGGSFAVTQFFTSNYIGPELPDITSALVSIVSLALFLKVWRPKNTET
                     AISMGQSAGAMVVNKPSSGGPVPSEYSLGQIIRAWSPFLILTVLVTIWTMKPFKALFA
                     PGGAFYSLVINFQIPHLHQQVLKAAPIVAQPTPMDAVFKFDPLSAGGTAIFIAAIISI
                     FILGVGIKKGIGVFAETLISLKWPILSIGMVLAFAFVTNYSGMSTTLALVLAGTGVMF
                     PFFSPFLGWLGVFLTGSDTSSNALFGSLQSTTAQQINVSDTLLVAANTSGGVTGKMIS
                     PQSIAVACAATGMVGRESELFRYTVKHSLIFASVIGVITLLQAYVFTGMLVS"
BASE COUNT         2484 a         2707 c         3023 g         2489 t
ORIGIN      
        1 tttcaccgtt aattatttgt tatccacaga gatatggaat gcgatctgct gatgattaaa
       61 attgaaaaag taattaataa aaatgacctt aaggcattta tcgcttttcc gtcatcactt
      121 tatcccgacg atccaaactg gataccccct ttattcatag aacgcaacga gcatttgtct
      181 gcgaaaaatc cggggacgga ccatatcatc tggcaggcgt gggtggcaaa aaaagcgggg
      241 cagatagttg ggcgtattac cgcgcaaata gataccttgc accgtgagcg ttacggtgaa
      301 gataccggtc atttcggcat gattgacgcc attgatgatc cgcaggtttt tgccgcgttg
      361 tttggcgcag cggaagcgtg gttgaagtca caaggtgcaa gtaagatcag cgggcctttc
      421 agcctgaata tcaatcagga aagcggatta ctgattgaag gttttgacac accaccctgt
      481 gcgatgatgc cacacggcaa accgtggtat gccgcgcata ttgaacaact gggttatcac
      541 aaaggcattg atttactggc gtggtggatg cagcgaaccg atctcacttt ctctccggcg
      601 ctaaaaaaac tgatggatca ggtgcgcaaa aaggtgacca ttcgctgcat caatcgtcag
      661 cggtttgccg aagagatgca gatcctgcgt gagattttca actctggctg gcagcacaac
      721 tggggatttg tgccgtttac cgaacatgaa ttcgcgacca tgggcgatca acttaaatat
      781 ctggtgccgg acgatatgat ctacatcgct gagattgatt ctgcaccctg cgcgtttatt
      841 gtcggcttgc cgaacatcaa cgaggcgatt gccgatctga acggatcgct ctttcccttc
      901 ggctgggcaa aattgctgtg gcgtttgaaa gtcagcggtg tgcgaactgc gcgagtaccg
      961 ctgatgggcg tgcgcgacga gtatcagttc agccgcatcg gcccggtgat tgcgctgtta
     1021 ttgattgaag ccttacgcga tccgtttgcc cgccggaaga tcgatgcgct ggagatgtca
     1081 tggatcctcg aaaccaatac aggcatgaat aacatgctgg aacgcattgg ggcggagccg
     1141 tacaagcgtt accgattgta tgaaaagcag atttaatacc agctaactca ggttcatctc
     1201 cagcggcacc gccgagcgaa tcaaatggtg gccttccagc tcgatatcgt ggagattctt
     1261 tttcacggtc cgcacatgat cgcgtgctgc gcgctgggcg acgtgcggca gccgctgcaa
     1321 caccgcgttg tagatcctcg catgctggcg atcgatctgc tttttttgct gtggtcgatg
     1381 gtagagatta tttacgctgg caaacactga attaaacatc agatcggtca atgattgcag
     1441 cgtaaacacc agcacctgat tgtgagaagc ctgacaaatg gcgagatgga aagcgtgatc
     1501 caactgcgca tgttcgatca gcgaaatctc tttgttgttc tcactggcgg cgagcatttt
     1561 ttcataacag cgggttatca caacaaaatc agcctgcgtt cccagcgttg ccgccagcct
     1621 tgccgattcg ccctccagta atgcgcgaac gtcgagcaga tcgtacagcg ttcgcggctg
     1681 cgtactgaac agatggatca gcgggctggt gtcctgcacc cgattaagcc gtgcgacacg
     1741 agaatcgcga ccctgcgccg tttcaataat cccgcgcccg cgcagcacgg tcagcccttc
     1801 acgcagtgcg gagcgtgaga agccgagctt ttcacacagt cgacgttccg agggaagtgg
     1861 ctgaccgacc ttcagtacgc cgtcgataat taaccgttcg atactctctg caaccacttc
     1921 gcaaataggg cgacgttcat ctttcattcc cggacctcgt gcacaggtag gaccaatttt
     1981 tctgttctta actcgcaaaa cacgcacatc acgtaagtga ttatgttaca tcaatttaac
     2041 attgagttaa ccaaggcaag gtcacagagc tggaaaaaaa atggtctgac cggtagctaa
     2101 agagatagac gaaaacgaaa agcccgctta ataactgttc acagaagcag cgcgcaaaaa
     2161 tcagctgcca cacaacacaa caaagcgaag cctactcatg agcatcttgt acgaagagcg
     2221 tcttgatggc gctttacccg atgtcgaccg cacatcggta ctgatggcac tgcgtgagca
     2281 tgtccctgga cttgagatcc tgcataccga tgaggagatc attccttacg agtgtgacgg
     2341 gttgagcgcg tatcgcacgc gtccattact ggttgttctg cctaagcaaa tggaacaggt
     2401 gacagcgatt cttgctgtct gccatcgcct gcgtgtaccg gtggtgaccc gtggtgcagg
     2461 caccgggctt tctggtggcg cgctgccgct ggaaaaaggt gtgttgttgg tgatggcgcg
     2521 ctttaaagag atcctcgaca ttaaccccgt tggtcgccgc gcgcgcgtgc agccaggcgt
     2581 gcgtaacctg gcgatctccc aggccgttgc accgcataat ctctactacg caccggaccc
     2641 ttcctcacaa atcgcctgtt ccattggcgg caacgtggca gaaaatgccg gcggcgtcca
     2701 ctgcctgaaa tatggtctga ccgtacataa cctgctgaaa attgaagtgc aaacgctgga
     2761 cggcgaggcg ctgacgctgg gatcggacgc gctggattca cctggttttg acctgctggc
     2821 gctgttcacc ggatcggaag gtatgctcgg cgtgaccacc gaagtgacgg taaaactgct
     2881 gccgaagccg cccgtggcgc gggttctgtt agccagcttt gactcggtag aaaaagccgg
     2941 acttgcagtt ggtgacatca tcgccaatgg cattatcccc ggcgggctgg agatgatgga
     3001 taacctgtcg atccgcgcgg cggaagattt tattcatgcc ggttatcccg tcgacgccga
     3061 agcaattttg ttatgcgagc tggacggcgt ggagtctgac gtacaggaag actgcgagcg
     3121 ggttaacgac atcttgttga aagcgggcgc gactgacgtc cgtctggcac aggacgaagc
     3181 agagcgcgta cgtttctggg ccggtcgcaa aaatgcgttc ccggcggtag gacgtatctc
     3241 cccggattac tactgcatgg atggcaccat cccgcgtcgc gccctgcctg gcgtactgga
     3301 aggcattgcc cgtttatcgc agcaatatga tttacgtgtt gccaacgtct ttcatgccgg
     3361 agatggcaac atgcacccgt taatcctttt cgatgccaac gaacccggtg aatttgcccg
     3421 cgcggaagag ctgggtggga agatcctcga actctgcgtt gaagttggcg gcagcatcag
     3481 tggggaacat ggcatcgggc gagaaaaaat caatcaaatg tgcgcccagt tcaacagcga
     3541 tgaaatcacg accttccatg cggtcaaggc ggcgtttgac cccgatggtt tgctgaaccc
     3601 tgggaaaaac attcccacgc tacaccgctg tgctgaattt ggtgccatgc atgtgcatca
     3661 cggtcattta cctttccctg aactggagcg tttctgatgc tacgcgagtg tgattacagc
     3721 caggcgctgc tggagcaggt gaatcaggca attagcgata aaacgccgct ggtgattcag
     3781 ggcagcaata gcaaagcctt tttaggtcgc cctgtcaccg ggcaaacgct ggatgtgcgt
     3841 tgtcatcgcg gcattgttaa ttacgacccg accgagctgg tgataaccgc gcgtgccgga
     3901 acgccgctgg tggcgattga agcggcgctg gagagcgccg ggcaaatgct tccctgcgag
     3961 ccgccgcatt atggtgaaga agccacctgg ggtgggatgg tcgcctgcgg gctggcgggg
     4021 ccgcgtcgcc cgtggagcgg ttcggtccgc gattttgtcc tcggcacgcg catcattacc
     4081 ggcgctggaa aacatctgcg ttttggtggc gaagtgatga aaaacgttgc cggatacgat
     4141 ctctcacggt taatggccgg aagctacggt tgtcttggcg tgctcactga aatctcgatg
     4201 aaagtgttac cgcgaccgcg cgcctccctg agcctgcgtc gggaaatcag cctgcaagaa
     4261 gccatgaacg aaatcgccca gtggcaactc cagccgctac ccattagtgg cttatgttac
     4321 ttcgacaatg cgttgtggat ccgccttgag ggcggcgaag gatcggtaaa agcggcgcgt
     4381 gaactgctgg ggggcgaaga ggttgcgggt cagttctggc agcaattgcg tgaacaacaa
     4441 ctgccgttct tctcgttacc aggtacctta tggcgcattt cattacccag cgatgcgccg
     4501 atgatggatt tacccggcga gcaactgatc gactggggcg gagcgttacg ctggctgaaa
     4561 tcgacagccg aggacaatca aatccatcgc atcgcccgca acgctggcgg tcatgcgacc
     4621 cgctttagtg ccggagatgg tggctttgcc ccgctatcgg ctcctttatt ccgctatcac
     4681 cagcagctta aacagcagct cgacccttgc ggcgtgttta accccggtcg catgtacgcg
     4741 gaactttgag gagcaggcta tgcaaaccca attaactgaa gagatgcggc agaacgcgcg
     4801 cgcgctggaa gccgacagca tcctgcgcgc ctgtgttcac tgcggatttt gtaccgcaac
     4861 ctgcccaacc tatcagcttc tgggcgatga actggacggg ccgcgcgggc gcatctatct
     4921 gattaaacag gtgctggaag gcaacgaagt cacgcttaaa acacaggagc atctcgatcg
     4981 ctgcctcact tgccgcaatt gtgaaaccac ctgtccttct ggtgtgcgct atcacaattt
     5041 gctggatatc gggcgtgata ttgtcgagca gaaagtgaaa cgcccactgc cggagcgaat
     5101 gctgcgcgaa ggattgcgcc aggtagtgcc gcgtccggcg gtcttccgtg cgctgacgca
     5161 ggtagggctg gtgctgcgac cgtttttacc ggaacaggtc agagcaaaac tgcctgctga
     5221 aacggtgaaa gctaaaccgc gtccgccgct gcgccataag cgtcgggttt taatgctgga
     5281 aggctgcgcc cagcctacgc tttcgcccaa caccaacgcg gcaactgcgc gagtgctgga
     5341 tcgtctgggg atcagcgtca tgtcagctaa cgaagcaggc tgttgtggcg cggtggacta
     5401 tcatcttaat gcgcaggaga aagggctgga acgggcgcgc aataatattg atgcctggtg
     5461 gcccgcgatt gaagcaggtg ccgaggcaat tttgcaaacc gccagcggtt gcggcgcgtt
     5521 tgtcaaagag tacgggcaga tgctgaaaaa cgatgcgtta tatgccgata aagcgcgtca
     5581 agtcagtgaa ctggcggtcg atttagtcga gcttctgcgc gaggaaccgc tggaaaaact
     5641 ggcagttcgc ggcgataaaa aactggcctt ccactgcccg tgtaccctac aacatgcgca
     5701 aaagctgaac ggcgaagtgg aaaaagtgtt gcttcgtctt ggatttacct taacggacgt
     5761 tcccgacagc catctgtgct gcggttcagc gggaacatat gcgttaacgc atcccgatct
     5821 ggcacgccag ctgcgggata acaaaatgaa tgcgctggaa agcggcaaac cggaaatgat
     5881 cgtcaccgcc aacattggtt gccagacgca tctggcgagc gccggtcgta cctctgtgcg
     5941 tcactggatt gaaattgtag aacaagccct tgaaaaggaa taacaaaatg aaaactaaag
     6001 tcattcttag ccagcaaatg gcgagtgcaa ttattgccgc aggtcaggaa gaggcgcaga
     6061 aaaataactg gtcggtttcc attgctgttg ccgatgacgg cggtcatctg ctggcgttaa
     6121 gtcgcatgga cgattgcgcg ccgattgcgg cttacatctc ccaggagaaa gcgcgtaccg
     6181 ccgcgctggg gcgtcgtgaa actaagggct atgaagagat ggtgaacaac ggacgtaccg
     6241 cgttcgtgac tgcgccgtta ctgacgtcgc tggaaggcgg cgtaccagtt gttgtggatg
     6301 ggcaaattat tggtgccgtg ggcgtttctg gtttaaccgg agcacaggat gcgcaggtcg
     6361 cgaaagcggc agcagcggtg ttggcgaaat aagcgaaaac gaggagataa acaatgagtc
     6421 aaaccataac ccagggccgt ttacgcattg acgccaattt taaacgtttt gtggatgaag
     6481 aagttttacc gggaacaggg ctggacgctg cggcgttctg gcgcaatttt gatgaaatcg
     6541 ttcacgattt ggcaccagaa aatcgtcagt tgctggcaga acgcgatcgc attcaggcgg
     6601 cgcttgatga gtggcatcgc agcaatccgg ggccggtaaa agataaagcg gcctataaat
     6661 ctttcctgcg tgaactgggc tacctggtgc cgcaactgga gcgcgtgacg gtggaaacca
     6721 cgggcattga cagcgaaatc accagtcagg cggggccaca gctggtggtt ccggcaatga
     6781 acgcccgcta cgcgctgaac gcggcgaacg ctcgctgggg ctcactgtac gatgcgttat
     6841 acggcagcga catcatcccg caggaagggg cgatggtcag cggctacgat ccgcaacgcg
     6901 gtgagcaggt tatcgcctgg gttcggcgtt tcctcgatga atctctaccg ctggaaaacg
     6961 gcagctatca ggatgtggtg gcgtttaagg tggtcgataa acaattacgc atccagttga
     7021 aaaatggtaa agaaaccacg ttacgtaccc cggcgcagtt tgtcggttac cgtggcgatg
     7081 ccgctgcgct gacctgcatt ttgctgaaaa ataacggcct gcatattgaa ctgcaaattg
     7141 atgccaacgg gcggattggc aaagacgatc cggcgcacat caacgatgtt atcgtcgaag
     7201 cggccatcag taccattctc gactgcgaag attcggtcgc ggcggttgat gcggaagata
     7261 aaatcctgct gtaccgcaat ctgctgggcc tgatgcaggg gactctgcaa gagaaaatgg
     7321 agaaaaacgg tcgacaaatc gtgcgtaaac tgaatgacga tcgtcattac accgccgccg
     7381 atggctctga aatttctctg cacggacgct cgctgctgtt tatccgcaac gtgggtcatt
     7441 tgatgaccat tcctgtgatt tgggacagcg aaggcaatga aatcccggaa ggcattcttg
     7501 atggcgtcat gactggcgcg atcgccctct atgatttaaa agtgcagaaa aactcgcgca
     7561 ctggcagcgt ctatattgtg aaaccgaaaa tgcacggtcc gcaggaagtg gcgttcgcca
     7621 acaaactgtt tacccgcatt gagacaatgc tcggtatggc accgaatacc ctgaaaatgg
     7681 gcattatgga tgaagaacgt cggacctcgc tgaacttgcg tagctgtatc gctcaggcgc
     7741 gcaatcgcgt ggcgttcatc aataccggtt tcctcgaccg taccggcgat gaaatgcatt
     7801 cggtgatgga agctggcccg atgctgcgta aaaaccagat gaaatcgacg ccgtggatca
     7861 aagcctacga gcgtaataac gtgctttccg gtctgttctg tgggctgcgc ggtaaagcgc
     7921 aaattggtaa aggcatgtgg gcaatgccgg acctgatggc agacatgtac agccagaagg
     7981 gcgaccaact gcgtgccggg gcaaacacag cctgggttcc gtcaccaacc gctgctacgc
     8041 tccatgcgct gcactaccac caaaccaacg tacagagcgt gcaagccaac attgcccaga
     8101 ccgagttcaa tgctgaattt gaaccgctgc tggacgatct gctgactatt ccggtggctg
     8161 aaaacgctaa ctggtcggtg gaagagatcc aacaagagct ggataacaac gtgcagggga
     8221 ttctggggta cgtggtgcgc tgggtggagc aggggattgg ttgttcaaaa gtgccggata
     8281 ttcacaatgt ggcgctgatg gaagaccgcg caacgctgcg tatctccagc cagcatatcg
     8341 ccaactggtt acgtcacggt attctgacca aagaacaggt gcaggcgtcg ctggagaata
     8401 tggcgaaagt ggttgatcag caaaacgctg gcgatccggc ttatcgtccg atggcgggga
     8461 atttcgctaa ctcgtgtgct tttaaagctg ccagcgattt aatcttcctc ggcgtgaaac
     8521 agccaaacgg ctataccgaa ccgttattac acgcctggcg tttacgcgaa aaagaaagtc
     8581 attaatagcg tcaaaaaaag ccccggcaag ttttattgtc ggggctatga tagtaactgc
     8641 ggtagtacat ttatcccgga aataaccgga gcgattatca gggtttaaca atattaaata
     8701 cccgtagcgc attactagcg ggcctaaaac aacaatatgg acatcttaac gatactctgc
     8761 gcctgcgtgt gcggaacaga aacccttacc cgatatactt gttatgccag aggtagcaat
     8821 tgcgttagcg gcgtactgtt gctgtaaagt ataacgccta tattttacag ttcagtcctc
     8881 ttttgcttat tacaacctta agtatatcaa gcatataaag ataataagag actgaacaat
     8941 atggttacct ggacccaaat gtatatgccg atgggaggac tggggctatc cgctctggtc
     9001 gccctgatcc cgataatatt cttcttcgtt gcactcgcgg tattacgtct gaaaggacat
     9061 gtcgctggag caataaccct tatcttatct atcctgattg cgatattcgc ctttaaaatg
     9121 ccgattgata tggcatttgc tgctgcaggc tatggcttta tttatggatt atggccaatt
     9181 gcgtggatta ttgtcgcggc ggtgttcctc tataaattaa ccgttgccag cggtcagttc
     9241 gatattatcc gcagctcggt tatctccatc accgacgatc agcgtttgca ggtgttactg
     9301 attggtttct cctttggtgc gttgctggaa ggagcggctg gctttggtgc gccggtggcg
     9361 attaccggtg cgctgctggt gggcctgggc ttcaaaccgt tatacgcggc ggggctgtgt
     9421 ctgattgcca acactgcgcc agtggcgttt ggtgcgttgg gcgtgccgat tctggtcgcc
     9481 ggtcaggtaa cgggaatcga tccgttccac attggcgcaa tggcgggacg tcagttaccg
     9541 ttcctgtcgg ttcttgtgcc gttctggctg gtagcaatga tggacggctg gaaaggggtg
     9601 aaagagacgt ggccagcggc gctggttgct gggggaagct tcgctgtcac tcagttcttt
     9661 acctctaact atattggtcc ggaactgccg gatattactt cggcgctggt gagtatcgtc
     9721 tcactcgctt tattccttaa agtctggcgg ccgaaaaata ccgaaacggc aatcagcatg
     9781 gggcaatccg caggtgcgat ggtggtaaat aagccatctt ctggcggtcc cgtgccttca
     9841 gaatatagtc tggggcaaat cattcgtgcg tggtcaccgt ttttaatctt aacggtgctg
     9901 gtcaccatct ggaccatgaa gccgtttaaa gcgttatttg ctccgggcgg cgcgttttat
     9961 tcactggtga ttaatttcca gatccctcat ttgcatcaac aagtgttgaa agcggcaccc
    10021 attgtcgccc aaccaacgcc aatggatgcg gtgtttaaat tcgaccctct ctcggctggc
    10081 ggcaccgcta tttttattgc ggcgattatc tctatcttca tcctcggcgt gggcatcaag
    10141 aaagggattg gcgtctttgc cgaaacgcta attagtctga agtggccgat attgtcgatt
    10201 ggcatggtgc tggcgttcgc cttcgtcacc aactattccg gcatgtccac cacgttggcg
    10261 ctggtactgg caggtacagg cgtgatgttc ccgtttttct caccgttcct cggctggctg
    10321 ggggtattcc ttaccggctc ggacacttct tcaaacgccc tgtttggttc actgcaatcg
    10381 accacggcgc agcaaatcaa cgtctctgac actctgctgg tggcagcaaa taccagcggc
    10441 ggcgtaactg gcaagatgat ctccccgcaa tctatcgccg tggcctgcgc cgcgacgggc
    10501 atggtgggcc gagaatctga actattccgc tacaccgtga agcacagtct gatttttgcc
    10561 agcgttatcg gcgttatcac gttgttgcag gcgtatgtgt ttactggaat gttggtctcg
    10621 taaatcaata atgccggatg atcgttaata tcatccggct tcatttacat tattctgtct
    10681 tattaattga aaattatttc tcg
//
LOCUS       DAPGUL010000143        10562 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.146, whole genome shotgun sequence.
ACCESSION   DAPGUL010000143 DAPGUL010000000
VERSION     DAPGUL010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10562)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10562)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10562
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.146"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..277)
                     /locus_tag="RHX21_004049"
     CDS             complement(<1..277)
                     /locus_tag="RHX21_004049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000147044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDV1989166.1"
                     /translation="MTGKNRVVLPALLALGLISTNANASDPCASVLCLYGKAVGQGGG
                     SECRSAEKDFFNILKKKKGSIRWSKTFDARKAFLNQCSTADPAAISKI"
     gene            complement(261..680)
                     /locus_tag="RHX21_004050"
     CDS             complement(261..680)
                     /locus_tag="RHX21_004050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cag pathogenicity island Cag12 family protein"
                     /protein_id="HDV1989167.1"
                     /translation="MKKLVFLLISILAGCSSPPEPTPVQFEKANEVINPSLPYVPDFH
                     GVIKSDVSGKGWVYEITSLSGVQARTPTFYYALAHADRIVVTTHDAGLWFRIRDLLKM
                     EGATAVVEWRNEKSFLPEQGKIVFIKAQNEVKNDWKK"
     gene            complement(692..2554)
                     /locus_tag="RHX21_004051"
     CDS             complement(692..2554)
                     /locus_tag="RHX21_004051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HDV1989168.1"
                     /translation="MKTFNKSQSVFIFAVMLVAAWFAGSFIFFVLYFSQIKNLKPLKA
                     VFRSIDAYRMDIFTDSLTLSVVTTDIRVLAFVALGAGFVVSLIIPVAALIKLNEKKDN
                     IFGDARFATTNDIRESNSFTLDGDEKDGIIVGIKDKKIIRYVGAAFSAMGAGTRAGKG
                     AGIVITNLMKYWWSVIILDPKRECFNITSLIRKVILGHEVYKFDPFSPVTHRFNPLYY
                     VSMGTSEGFNQLENLALIIYPYKTDGADAGSYLNKTAGGVFKSYAVALWFMIKNDKAG
                     LKTLDIEPVFSMSKINQLFERAEPEHLLSFMNDIRSELRGKDKTLADIGVAGLKAFIE
                     MEDKTKAQLKSNFLNGLSPFANPNVANATDGNDFDLRQVRKKRMTIYFCISGDNARLA
                     EKITNIFFQLAIQVNLEKMPTDDPEIKHDCLFLLDEFPSIGAVDYIKSKSGLIAGYKL
                     KLLIVYQVGSQLEEIYSYAGSKTLLASAPCKIVYSASDVKDARELSEAMGTRTVTIGS
                     KSKSRSRGGTSRSESESLIERPLVTTNELLTLKFSEEILAMKGENPIRCEKAFYYLHE
                     YFFGDFVKVAPELANIFPRKKGKLVMPPQKVFENEIVAKGYLAVKEVPDLDKAA"
     gene            complement(2541..3569)
                     /gene="virB11"
                     /locus_tag="RHX21_004052"
     CDS             complement(2541..3569)
                     /gene="virB11"
                     /locus_tag="RHX21_004052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="HDV1989169.1"
                     /translation="MSGVIPVSISNKSLDFYKNQVFQSFLDIEGLTEIAVNRPGEIWT
                     EINGDWTFHNNDGVTFDFCKRFSQTLASFRGDEIGDTKPLLSATLESGERVQVVFPPA
                     CERNTISITIRKPSTRQITHKEYVANGFYDYVQSGKKHRTYDDELLDLFRARNIAAFM
                     ELAVAAGKTIVFAGATGSGKTTYMKSLIDFIPLNTRLITIEDAEEIKFFIHKNYVHLF
                     YPSESGSDSGSIITAAKLIKSCLRMKPDRILLAEIKGGDAWDFVKVAGSGHSGSMTSI
                     HAASAKDAIIQMVTKCYQNRECQNLPFDVLRKIIMDSIDIVVHVGRDGVVRHMSDIYY
                     KGAECENF"
     gene            complement(3571..4689)
                     /locus_tag="RHX21_004053"
     CDS             complement(3571..4689)
                     /locus_tag="RHX21_004053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbI/VirB10 family protein"
                     /protein_id="HDV1989170.1"
                     /translation="MTDMKKTDDLVDDANQSKLESKPVHDIGDIRNKNNRMRSGFLFG
                     LMAVLVIGIFALKTYKNYFADDQQKASESTGDTSISQVSKIRTGLGQNFDPVENKAII
                     NPGATGSGNTVSDGHKEVPQEGFRKYLSIPVAGQGGSQTGASGSSRTSQTSEPQEERK
                     ESKENVPGKSGMKVTAINLDPDLYIEENRLIPCALTTRFVSDVAGRISCVFTEDVWSA
                     NHHTKLLEQGTKAFGRYQTGTLNHGQGRMFVMWEQLRTPDNKRIDMVNTAAAGPLGEA
                     GIDGWIDSHFWERFGGSLMLSMVQDVAAAAADNAPGKDRNVDYTENSRQAMAEMAKVA
                     LENSINIPPTMYKNQGDIITIMVGEDIDFSDIYELKVK"
     gene            complement(4682..5590)
                     /gene="virB9"
                     /locus_tag="RHX21_004054"
     CDS             complement(4682..5590)
                     /gene="virB9"
                     /locus_tag="RHX21_004054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001299943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein VirB9"
                     /protein_id="HDV1989171.1"
                     /translation="MMKKLFIATCLLLPGLVYSAATPLPSGFDARMQTVSYNGANTTV
                     IRSKTGFLTSVVFDEGEAVISAKAGFPAGWEITTDDNVVYINPRPVVQEQEGDEGEKL
                     KKVFQPTEKEWDTNLFVRTTKRIYSLDLILLSEEKQAQPAYVVQFRYPSEIAKKNAEE
                     VRLAKEKQEKLRQKKLISESFEKADAPKNWDYFMRVNEKYDSRRIAPDFAYDNGIFTF
                     LGFNSGKVFPAPFAVRDGQEQTLAFNVETKGKYKIMVIHNVNDKFVLRYGNSVVGVVN
                     KSFGKVLTDQRNTSSPAVERVEVNND"
     gene            complement(5587..6273)
                     /locus_tag="RHX21_004055"
     CDS             complement(5587..6273)
                     /locus_tag="RHX21_004055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="HDV1989172.1"
                     /translation="MSEKIEKKIETAKSFERQLYAENERSKKNAWRVAVAASLLSLCL
                     GAAICVLVPLKEKELAIVAVGEKTGRTELITQVKQEKILQSEALGRYFVNTYITLREG
                     YNYPSLQYDYETVQLYSSNTVKDDYLRLYNSDMAPDKIYHNNGSYVAVEVISNIISDA
                     TAPDKLASVRFKKTTRNFTTGQVSVSYWTARVTYRFEPEKSVKSSSRELNPLGFTVTS
                     YQTDREVRGE"
     gene            complement(6788..7882)
                     /locus_tag="RHX21_004056"
     CDS             complement(6788..7882)
                     /locus_tag="RHX21_004056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001677777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="HDV1989173.1"
                     /translation="MAQGFFVKYNSTVMDSVDKISSSYQTQFANDIMSLATVSVTLYV
                     LWKGYQILASKTQTPLQDLVWDLSKFAIIIMFITNADGYLTAATDALQGMKDGFSGGV
                     SVWQTLDNLWKSTQNLGAEIYSLDKSTYVKDQGVVGQFLIWTGSLILMAVSVVVFLTA
                     DVTMKLLIITAPIFIFCLMFGFIRSMFNNWLQSLFSSILTVLFASLVIRIAMDFQGMI
                     LSHAIRAAQTGNVNLVSTGAMGFMAGFLGALLVLIAKGFAVQLAGAGVEGAVQGAAMM
                     GLGAAGMATGKSLMLGGRAGLGFGLGMAGRTGMNSLSGKAGNLMGRGARTAAEWAGEK
                     GYQALAPTGALGMKARRLASLEKARARNAA"
     gene            complement(7894..8610)
                     /locus_tag="RHX21_004057"
     CDS             complement(7894..8610)
                     /locus_tag="RHX21_004057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein VirB5"
                     /protein_id="HDV1989174.1"
                     /translation="MKRVKTFMLISLLTASFYSSAGIPVAIDASPEWAVEAARWTERL
                     KQWSETAQHYQSQIQAYKDQLATATGIRNIAAFTNELSNLQSELTNIYKQGNSYISDF
                     TSNPEGALSSQAKNLFSKYGAFDMCNTGYERNDNLCKARIVSTAASIEQGNEINKQLS
                     NAMSQIQSLSSRIEASKDIKESQDLANALQAQSLKMQAIKMQYDVWNNKNKADHEMLI
                     TQEQEAFIKQQKEAEPLTFD"
     gene            complement(8622..>10562)
                     /locus_tag="RHX21_004058"
     CDS             complement(8622..>10562)
                     /locus_tag="RHX21_004058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDV1989175.1"
                     /translation="LLGMYEENGKVFSSQLSFYNYLLTGKLQKIRVTDSPVYNVLGGV
                     DVFFNHDTGQICRIDGNKFFRSIEIKDFCSETASGVFDVLQYSDADYIITHSYTSMSK
                     SEALSTIKRAEKQLKSTEDDAVTQLQELEKAKNDIVSGDISFGYYHFTLMVMADSIRE
                     LDESVSKITADFTDLGIIPALSTMSLPAAYFAQLPAVFHLRPRLSPVSNVNFVELASF
                     HNFYQGKRDKNCWTEAVAILKTPSKQAYYLNLHNSVLFKDETGEKNLANTKVIGTAGS
                     GKTMFLSYLACSLQKYNNPETFADSAKNKKLTCVFLDKDRGAELCIRMLGGEYYTVKS
                     GEPTGWNPFALEATKRNRIFVKQLMEILCTRNGERLSTRERLLISESVDAVMDFPPGE
                     MREYGITRMLEHLMQRDDRDEQENGIILRLSQWANGQAHGWVFDNAKDTFNIQHVNNF
                     GIDGTEFLDDPMVCAPITFYLLYRITQLLDGRRLVIFLDEFWKWLQDEAFSDFVYNKL
                     KTIRKLNGLVIPATQSPDEILKNKISRAVVEVCSTSIYLANPDADYNDYVEGLKLTPE
                     EFNIVKNLDPMSRQFLIKKSSLKKGDGKSFSALATLDLSGLGGYLKILSASADNLEIF
                     ESIYHEGMEPDDWVPEYLERAI"
BASE COUNT         3087 a         2511 c         1823 g         3141 t
ORIGIN      
        1 taatttttga gatagcagcc ggatcagccg ttgaacactg attcagaaat gctttacggg
       61 catcaaatgt tttactccag cgaatgcttc cttttttctt tttcagaata ttaaaaaaat
      121 ccttttcagc acttctgcac tcactccctc caccttgccc gactgctttt ccatataagc
      181 aaagtaccga agcgcaagga tcagatgcat tagcatttgt tgatattaat cctaacgcca
      241 gcaaggcagg taaaaccact ctattttttc cagtcatttt tcacctcgtt ttgtgcttta
      301 atgaaaacta tttttccctg ttcaggtaaa aaacttttct cgtttcgcca ctccacgact
      361 gctgttgccc cttccatctt caacagatct ctgattcgaa accacagccc agcatcatgt
      421 gttgtcacta caatcctgtc cgcatgagcc agagcgtaat aaaacgtcgg cgttctggcc
      481 tgtactccgg ataaggaagt gatctcataa acccatcctt taccgctaac gtctgacttt
      541 atgacaccgt gaaaatcggg gacatatggc aatgagggat tgatcacttc atttgccttt
      601 tcaaactgca cgggtgttgg ctctggcggt gatgaacaac cagcaaggat agaaatcaat
      661 aaaaacacta acttcttcat catgttctcc tttatgccgc tttatcgaga tcaggaactt
      721 cttttactgc cagataccct tttgcgacga tttcattttc aaatactttc tgtggaggca
      781 taaccaactt tcctttcttc ctggggaaaa tgtttgcaag ttccggagca accttcacaa
      841 aatcaccaaa gaaatactca tggagatagt agaatgcctt ttcacaacga atcgggtttt
      901 ctcccttcat tgccaggatt tcttcactaa atttcagtgt aagtagttca tttgttgtta
      961 ccagtggacg ctcaataagg ctttctgatt cagatctcga tgttcctcca cgactacgac
     1021 ttttgctttt cgaaccgata gttactgttc gtgttcccat cgcttctgat aactcccgcg
     1081 catctttaac atcagaagcg gaataaacga ttttacaggg tgcacttgcc agtaatgttt
     1141 tactgcctgc ataactgtag atttcctcaa gctgagagcc gacctggtaa acaatcaaca
     1201 atttcagctt gtaaccagca atgagtccag atttactctt gatgtaatct acagcaccaa
     1261 ttgacgggaa ttcatccagt agaaaaaggc agtcatgttt tatttccgga tcatccgttg
     1321 gcatcttttc aagattcacc tgtatagcaa gctgaaagaa aatatttgtt attttttcag
     1381 ccaacctggc attatcacca gaaatacaga aataaattgt catccgcttt ttccgcacct
     1441 gccgcaaatc aaaatcattt ccatcagtag catttgccac attggggtta gcaaacggtg
     1501 ataatccatt aagaaagttg cttttgagtt gtgcttttgt tttatcctcc atctcaatga
     1561 atgccttaag gccagcgaca ccaatatcag caagcgtttt gtctttcccc cttaattctg
     1621 aacgaatatc attcatgaat gaaagaagat gttcgggttc tgcacgctca aaaagctgat
     1681 taattttaga cattgagaag acaggctcaa tatcaagcgt ttttagtcca gccttatcat
     1741 tcttaatcat aaaccataaa gcgacagcat aagatttaaa aacacccccc gccgtcttat
     1801 taagatagct accagcatcc gcaccatctg tcttataggg gtaaataatc aacgcaagat
     1861 tttcaagctg attaaaacct tcactcgttc ccatgctgac ataatacaaa gggttaaagc
     1921 ggtgcgttac cggactaaag ggatcaaatt tataaacctc atgacctaaa atcaccttcc
     1981 tgataagact ggtgatatta aaacactccc tttttggatc gagaataata acactccacc
     2041 agtacttcat aagattagtg atgactatac ctgcaccttt accagccctt gttccggctc
     2101 ccatcgcact gaatgctgct cccacatagc gtatgatttt cttgtctttt ataccaacga
     2161 taatcccgtc tttttcgtca ccgtcaagcg tgaaactgtt agactcacga atatcattag
     2221 ttgtcgcaaa tcgcgcatca ccaaaaatat tatctttctt ctcgttcagt tttatcaacg
     2281 ccgcaacagg gataataaga gacacgacaa atcctgctcc aagtgcaaca aaggctaaaa
     2341 ctctgatatc cgtagtcaca acagataaag taaggctgtc tgtaaaaata tccatcctgt
     2401 acgcatcaat ggatctgaac acagccttca atggtttcag attctttatc tggctgaagt
     2461 aaagcacaaa gaaaataaat gaacctgcaa accatgccgc aacaagcata acagcgaata
     2521 taaaaacaga ttgcgactta ttaaaagttt tcacattcag cccctttgta atagatgtcg
     2581 ctcatatgcc tgacaacacc atccctgcct acatgaacaa caatatcaat actgtccata
     2641 atgattttac gaagaacatc aaaaggaaga ttttgacatt ctctgttctg ataacatttt
     2701 gtcaccatct gaatgatggc atcttttgcc gaggccgcgt gaatggacgt catgcttcca
     2761 ctgtgaccag aaccagcaac tttcacaaaa tcccaggcat cgccaccttt aatttccgcc
     2821 agtaaaattc tgtcaggttt cattctcaaa caggatttga ttaatttcgc tgctgttatg
     2881 atagagccgg aatcactgcc ggattccgaa gggtaaaaaa gatgcacata atttttatga
     2941 ataaaaaatt tgatttcctc cgcatcttca atcgtaatca gccgcgtatt caatggtatg
     3001 aaatcgataa gactcttcat ataggttgtt ttaccggaac ccgttgctcc ggcaaataca
     3061 atggttttcc ctgctgctac ggcaagctcc ataaaagcag cgatatttct cgctctgaat
     3121 aaatcaagaa gctcatcatc gtatgtcctg tgtttttttc ctgactggac ataatcataa
     3181 aaaccgttcg ccacatattc tttatgcgtt atctgccgtg tcgatggttt acgtatagtg
     3241 attgaaatag tatttctctc acatgcagga ggaaaaacga cctgtacacg ttctcctgat
     3301 tccagtgttg ctgaaagtaa tggcttggta tcaccgattt catctccccg aaatgatgcc
     3361 agcgtctgag aaaaacgttt acaaaaatca aaggtcacac cgtcattatt atggaatgtc
     3421 cagtcaccat taatttccgt ccagatttca ccaggacggt tgacagcaat ttctgttagc
     3481 ccttcaatat caagaaaaga ctggaatact tgatttttat aaaaatcgag cgatttattg
     3541 ctaatgctga caggaataac gccactcata ctattttacc tttaactcat agatatcaga
     3601 aaaatcaatg tcttccccga ccataatagt gattatgtca ccttggtttt tatacattgt
     3661 tggaggaata tttatcgaat tctcaagtgc aactttagcc atttcagcca ttgcctgtcg
     3721 tgagttttcg gtataatcca cattacgatc tttaccaggt gcattatccg ccgccgccgc
     3781 cgctacatcc tgaaccatac tgagcataag agaaccacca aaacgctccc agaagtgaga
     3841 atcgatccat ccatcaatgc ctgcttcccc caggggacca gccgctgctg tatttaccat
     3901 atcgattcgt ttattatcag gcgtccgcaa ctgctcccac ataacgaaca ttctgccctg
     3961 tccatgattc agcgttccgg tctggtaacg accaaaagcc ttagttccct gttccagtaa
     4021 ttttgtgtgg tgattagcac tccatacatc ttctgtaaaa acacaactga tacgacctgc
     4081 aacatcagaa acaaagcgtg tggttaaagc acacggtata agcctgtttt cctcaatata
     4141 gagatcagga tcgagattaa tcgcagtcac tttcattcct gatttaccag gcacattttc
     4201 ttttgattct ttcctttctt cctgtggctc tgatgtctgc gatgtcctgc tgctgccact
     4261 cgcgccagtc tgactccctc cctgaccagc aacaggtatt gacaaatatt tcctgaaccc
     4321 ctcctgtggc acttctttat gaccgtcaga aacagtatta ccagaaccag tagcgcctgg
     4381 attgataatt gctttgttct caacagggtc aaaattctga ccaagaccag tacggatttt
     4441 acttacctga gaaatgctgg tatcgcctgt tgattctgat gctttctgct ggtcatctgc
     4501 aaaataattt ttatatgttt tcagcgcaaa aataccaata actaatacag ccatcagacc
     4561 aaacagaaag ccagaacgca tacgattatt tttgttcctg atatcaccga tatcatgaac
     4621 gggtttactt tccagctttg actgattcgc atcatcaact aaatcatctg tttttttcat
     4681 atcagtcatt attcacctca acacgttcta ccgcaggaga agatgtattc ctctggtcgg
     4741 ttaatacttt tccgaaagat ttattcacaa caccaacaac gctgtttcca tagcgtaaaa
     4801 caaatttgtc attaacgttg tggataacca tgattttata cttgcctttt gtttccacat
     4861 taaaagcaag tgtctgttcc tgaccatctc ttacagcaaa tggagctggg aatactttcc
     4921 ctgagttaaa acctaaaaag gtaaatatgc cattatcata agcaaaatca ggggcgatac
     4981 gacgactgtc atatttttca ttgactcgca tgaaataatc ccagttttta ggcgcatcgg
     5041 ctttttcaaa actttcagaa atcagtttct tctgtctgag tttttcctgt ttttcttttg
     5101 ccagccttac ttcttctgca ttctttttcg ctatttctga tggatagcgg aattgtacaa
     5161 cataagcagg ttgcgcttgt ttttcttctg acagaaggat tagatcaaga ctgtaaatcc
     5221 gctttgttgt tctgacaaaa agattcgtgt cccattcctt ttctgttggc tggaaaacct
     5281 ttttcagttt ttcgccttca tcgccttcct gttcctgaac aacgggacgc ggattgatgt
     5341 aaacaacatt atcatcggtt gtgatttccc atccggcagg aaaaccagcc tttgcactga
     5401 taacagcctc accttcatca aaaacaactg atgtgagaaa tcctgtcttt gaccggataa
     5461 cggtcgtatt cgcaccgtta taactcacag tctgcatcct tgcatcaaat ccagaaggta
     5521 acggagtcgc tgctgaatac acaagcccag gaagcaataa acatgtagca ataaataatt
     5581 tcttcatcat tcccccctga cttcccgatc tgtctggtaa ctggttaccg taaaaccgag
     5641 aggattaagc tcacgactgg aacttttaac cgacttttct ggttcaaaac gatatgtcac
     5701 acgagccgtc cagtatgaaa ctgaaacctg tccggtcgtg aagtttctcg tcgttttttt
     5761 aaaacgcaca gaggccagtt tatctggcgc ggttgcgtca gaaataatat tggagatgac
     5821 ctcaaccgca acgtaagaac cgttattatg ataaatttta tcaggagcca tatcgctgtt
     5881 atacagacga agataatcgt cctttactgt attcgagcta tatagctgta cagtctcata
     5941 atcatactga agagacggat aattataacc ttcacgtaaa gtaatatacg tgtttacaaa
     6001 ataccgccca agcgcttcag attgcaggat cttttcctgt ttaacctgag taatcagttc
     6061 tgtacggcct gttttttcgc caacagccac aatagcaagc tctttttctt ttaatggcac
     6121 aagaacacaa attgcagccc caagacataa ggacagtaat gatgctgcca ctgcaacacg
     6181 ccatgcattt ttcttagacc gttcattttc tgcatagagt tgtctttcga aggatttagc
     6241 tgtctcaatc ttcttttcga ttttttcact cataactgat tacctggctg tggttaatgg
     6301 gttccagttc gccggaaaca tcagaaggaa gggtattcct tgtggtacat ccggaaatct
     6361 gaaacaggaa aaacaaaaga atcacacatc gcataaattc accttattaa gcgttcacga
     6421 acacctttaa gagataaagg ccaagatgaa gaaaaagaat cccaccaata agaagcaaaa
     6481 agcgaagatc catacccttt ctccatttcc ccgcaagccc taaaccaagt cttattcctg
     6541 cgaagcaggt aaacactcct aaaagaagga ttaggacaaa ataaagtatc atgacaaaat
     6601 aatgaagcat gtcacaacca gctctgactg attccaccta agaccttaaa taaggtaatt
     6661 cccgtgatta aaataataag ctgggttatt agctttctct tcctgctcca tccggaggtg
     6721 atatgtttat caacaaacgt cagtatccag ttcagggaca tcacataaaa aaaacgtttc
     6781 attatattca tgcggcattc ctcgctcgtg ctttttccag ggatgcaagt cttctcgcct
     6841 tcatccccaa agcacctgtc ggagccagcg cctgatatcc cttttcaccc gcccattcag
     6901 cggctgttcg cgcaccacgc cccatcagat tccctgcttt cccagataaa gaattcatgc
     6961 ccgttcttcc ggccatccct aagccaaaac ctaaaccagc acgaccgcca agcatcagag
     7021 acttaccagt agccatacca gcagcaccca gccccatcat ggctgcgccc tgaacagcac
     7081 cttcaacacc tgcacctgct aactggacag caaaaccttt agctataaga accaataaag
     7141 cccccaaaaa cccagccata aagcccatag cacctgtaga tacaagattt acatttcctg
     7201 tttgtgcagc acgaatagca tgggaaagga tcatcccttg aaaatccatt gctatccgaa
     7261 tcactaaact ggcaaataga actgtcagaa tactggagaa taacgattgt aaccaattat
     7321 taaacatgct ccgaataaaa ccaaacataa gacaaaagat aaatatcggt gctgtaataa
     7381 tcaggagttt catcgttaca tctgctgtta aaaaaacaac cacactaaca gccattaaaa
     7441 taagcgagcc agtccatatt aaaaactgtc caactacacc ttgatcttta acatatgttg
     7501 atttatctaa agagtatatt tccgcgccaa gattttgcgt acttttccat aagttatcta
     7561 aagtttgcca gacactcacc cctccagaaa aaccatcttt catgccttgc aacgcatcag
     7621 tggccgcagt taaataccca tccgcattag ttataaacat gattatgatt gcaaattttg
     7681 atagatccca tactaaatcc tgcaagggcg tctgagtttt actggcaagt atttgatatc
     7741 ctttccatag tacatataac gtaaccgata ccgtcgctaa cgacataata tcattagcaa
     7801 attgtgtttg ataactggag ctgattttat ctaccgaatc cataacggta gaattatatt
     7861 taacgaaaaa cccctgagcc atatatccac cttttaatca aaagttaatg gttcagcttc
     7921 tttctgctgt ttaataaagg cctcttgttc ttgtgtgatc aacatctcat gatctgcttt
     7981 atttttatta ttccagacat catactgcat ttttatcgcc tgcattttta acgactgcgc
     8041 ctgtaatgcg ttagccaaat cctgggattc tttgatatcc tttgaagcct caattcggct
     8101 acttaaactc tgaatctgag acattgcatt tgataactgc ttattgatct catttccctg
     8161 ttcaatactg gcagccgttg acacaatccg tgctttacag agattatcat tacgttcata
     8221 gcccgtatta cacatatcga aggctccata cttgctgaac agatttttag cctggctgct
     8281 caatgcacct tcgggattac tggtaaaatc agaaatataa ctgttcccct gcttataaat
     8341 atttgtcagt tctgattgta gattacttag ttcatttgtg aatgccgcaa tattccttat
     8401 acctgttgcc gtggctaact ggtctttata tgcctgaatc tgactctgat aatgttgcgc
     8461 agtttcggac cattgtttga gtcgttctgt ccatcttgcg gcttcaacag cccattccgg
     8521 actggcatca atagcaaccg gaattcctgc gctactataa aatgaagccg tcaataatga
     8581 tatcagcata aatgttttta cacgcttcat aaattcacct gtcagattgc ccgttcgaga
     8641 tattcaggaa cccagtcatc aggctccatt ccttcatgat aaatactttc aaaaatttcc
     8701 agattatctg cactagcaga caatattttc agatatccac caagtcccga taaatcaagt
     8761 gtcgcaagtg ctgaaaatga tttaccatcc ccctttttaa gactgctttt tttaatcagg
     8821 aactgtctcg acattggatc aagattttta acaatattaa attcttctgg tgtcagctta
     8881 agcccttcca cataatcatt gtaatcggca tcagggttag ccagataaat actggtgctg
     8941 catacttcaa ccacagcccg tgaaatctta ttcttcagta tttcatccgg agactgagtt
     9001 gccggaataa ccagcccgtt cagcttacga attgttttca gcttgttata gacaaagtcg
     9061 ctgaatgctt catcctgtag ccatttccag aactcatcca ggaagataac aagacgccga
     9121 ccgtcaagaa gctgcgtaat gcgatacagc agatagaaag taattggtgc acataccatc
     9181 ggatcatcaa gaaactcggt gccatcaatg ccaaaattat tgacatgctg aatattgaat
     9241 gtgtctttag cattatcaaa aacccagcca tgagcctgac cattagccca ttgggacaac
     9301 cgaaggataa tcccgttctc ctgctcatcc cgatcatctc tctgcataag atgctcaagc
     9361 attctggtaa tgccatattc ccgcatttcg ccaggaggaa aatccatcac agcatcaaca
     9421 ctttcgctaa taagcaatct ttctcttgtc gataatcttt caccatttct ggtacacaga
     9481 atctccatca gttgcttgac aaaaatacgg ttacgttttg ttgcctccag agcaaaagga
     9541 ttccatcctg tcggctcacc gctttttacg gtgtaatatt ccccaccaag cattcggata
     9601 cataattcag cccctctgtc cttatcaaga aagacacacg ttaacttctt attttttgca
     9661 gaatcagcaa aagtttcggg gttattgtat ttctgtaatg aacaggcaag atatgacaga
     9721 aacattgtct tacctgaacc cgccgttcct ataactttag tattagcaag attcttttca
     9781 cctgtttcat ctttaaacag tactgagtta tgtaaattca gataatacgc ctgtttgctt
     9841 ggtgttttga gaatagcaac cgcttctgtc cagcagtttt tatcgcgttt cccctggtag
     9901 aaattatgga atgatgccag ttcgacaaaa tttacattcg ataccggaga taaacgtggc
     9961 cttaaatgaa aaaccgccgg aagctgggca aaatatgccg ctggcaatga catggttgac
    10021 aatgccggaa taatgcccag gtcagtaaag tctgccgtaa ttttacttac agattcgtca
    10081 agctccctga tactgtccgc cattaccatt agcgtgaaat ggtagtaacc aaaggatata
    10141 tcaccggaca caatatcatt ttttgccttt tccagttcct gcaattgagt aaccgcatca
    10201 tcttctgtac tctttaactg tttttccgca cgtttaatgg tactcaatgc ttctgatttg
    10261 ctcatggatg tatatgaatg cgtaataata tagtcagcat cagaatactg gagcacatca
    10321 aaaacaccgg atgcagtctc actacagaaa tctttaattt caatagaacg aaagaattta
    10381 tttccatcaa tgcggcatat ctgtccggta tcatggttaa aaaacacatc cactccacca
    10441 agaacgttat acaccggaga atcagttact ctgatttttt gcaacttccc tgtcagaaga
    10501 taattataga atgacagttg agaagaaaat acctttccgt tctcctcata cataccaaga
    10561 ag
//
LOCUS       DAPGUL010000144        10492 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.147, whole genome shotgun sequence.
ACCESSION   DAPGUL010000144 DAPGUL010000000
VERSION     DAPGUL010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10492
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.147"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            111..686
                     /gene="ssuE"
                     /locus_tag="RHX21_004059"
     CDS             111..686
                     /gene="ssuE"
                     /locus_tag="RHX21_004059"
                     /EC_number="1.5.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HDV1989176.1"
                     /translation="MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFAP
                     EDLLYARFDSPALKTFTEQLQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVV
                     LPLATGGTVAHLLAVDYALKPVLSALKAQEILHGVFADDSQVIDYHHRPQFTPNLQTR
                     LDTALETFWQALHRRDVQVPDLLSLRGNVHA"
     gene            679..1638
                     /gene="ssuA"
                     /locus_tag="RHX21_004060"
     CDS             679..1638
                     /gene="ssuA"
                     /locus_tag="RHX21_004060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415456.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonate ABC transporter
                     substrate-binding protein SsuA"
                     /protein_id="HDV1989177.1"
                     /translation="MRNIIKLALAGLLSVSTFAVAAESSPEALRIGYQKGSIGMVLAK
                     SHQLLEKRYPQSKISWVEFPAGPQMLEALNVGSIDLGSTGDIPPIFAQAAGADLVYVG
                     VEPPKPKAEVILVAENSPIKTVADLKGHKVAFQKGSSSHNLLLRALRQAGLKFTDIQP
                     TYLTPADARAAFQQGNVDAWAIWDPYYSAALLQGGVRVLKDGTDLNQTGSFYLAARPY
                     AEKNGAFIQGVLATFSEADALTRSQREQSIALLAKTMGLPAPVIASYLDHRPPTTIKP
                     VNAEIAALQQQTADLFYENRLVPKKVDIRQRIWQPTQLEGKQL"
     gene            1635..2780
                     /gene="ssuD"
                     /locus_tag="RHX21_004061"
     CDS             1635..2780
                     /gene="ssuD"
                     /locus_tag="RHX21_004061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMNH2-dependent alkanesulfonate monooxygenase"
                     /protein_id="HDV1989178.1"
                     /translation="MSLNMFWFLPTHGDGHYLGTEEGSRPVDHGYLQQIAQAADRLGY
                     TGVLIPTGRSCEDAWLVAASMIPVTQRLKFLVALRPSVTSPTVAARQAATLDRLSNGR
                     ALFNLVTGSDPQELAGDGVFLDHSERYEASAEFTQVWRRLLLGETVNFNGKHIHVRGA
                     KLLFPPIQQPYPPLYFGGSSDVAQELAAEQVDLYLTWGEPPELVKEKIEQVRAKAAAH
                     GRKIRFGIRLHVIVRETNDEAWQAAERLISHLDDETIAKAQAAFARTDSVGQQRMAAL
                     HNGKRDNLEISPNLWAGVGLVRGGAGTALVGDGPTVAARINEYAALGIDSFVLSGYPH
                     LEEAYRVGELLFPHLDVAIPEIPQPQPLNPQGEAVANDFIPRKVAQS"
     gene            2791..3582
                     /gene="ssuC"
                     /locus_tag="RHX21_004062"
     CDS             2791..3582
                     /gene="ssuC"
                     /locus_tag="RHX21_004062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415454.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonate ABC transporter permease
                     SsuC"
                     /protein_id="HDV1989179.1"
                     /translation="MATPVKKWLLRVAPWFLPVGIVAVWQLASSVGWLSTRILPSPEG
                     VVTAFWTLSASGELWQHLAISSWRALIGFSIGGSLGLILGLISGLSRWGERLLDTSIQ
                     MLRNVPHLALIPLVILWFGIDESAKIFLVALGTLFPIYINTWHGIRNIDRGLVEMARS
                     YGLSGIPLFIHVILPGALPSIMVGVRFALGLMWLTLIVAETISANSGIGYLAMNAREF
                     LQTDVVVVAIILYALLGKLADVSAQLLERLWLRWNPAYHLKEATV"
     gene            3579..4346
                     /gene="ssuB"
                     /locus_tag="RHX21_004063"
     CDS             3579..4346
                     /gene="ssuB"
                     /locus_tag="RHX21_004063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonates ABC transporter ATP-binding
                     protein"
                     /protein_id="HDV1989180.1"
                     /translation="MNTARLNQGTPLLLNAVSKHYAENIVLNQLDLHIPAGQFVAVVG
                     RSGGGKSTLLRLLAGLETPTAGDVLAGTTPLAEIQEDTRMMFQDARLLPWKSVIDNVG
                     LGLKGQWRDAARRALAAVGLENRAGEWPAALSGGQKQRVALARALIHRPGLLLLDEPL
                     GALDALTRLEMQDLIVSLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEGKIGLDLTVD
                     IPRPRRLGSVRLAELEAEVLQRVMRRGHSEQLIRRHG"
     gene            complement(4553..7165)
                     /gene="pepN"
                     /locus_tag="RHX21_004064"
     CDS             complement(4553..7165)
                     /gene="pepN"
                     /locus_tag="RHX21_004064"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000193787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase N"
                     /protein_id="HDV1989181.1"
                     /translation="MTQQPQAKYRHDYRAPDYQITDIDLTFDLDAQKTVVTAVSQAVR
                     HGASDAPLRLNGEDLKLVSVHINDEPWTAWKEEEGALVISNLPERFTLKIINEISPAA
                     NTALEGLYQSGDALCTQCEAEGFRHITYYLDRPDVLARFTTKIIADKIKYPFLLSNGN
                     RVAQGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRG
                     NLDRAPWAMTSLKNSMKWDEERFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYV
                     LARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDL
                     GSRAVNRINNVRTMRGLQFAEDASPMAHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIH
                     TLLGEENFQKGMQLYFERHDGSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPIVTV
                     KDDYNPETEQYTLTISQRTPATPDQAEKQPLHIPFAIELYDNEGKVIPLQKGGHPVNS
                     VLNVTQAEQTFVFDNVYFQPVPALLCEFSAPVKLEYKWSDQQLTFLMRHARNDFSRWD
                     AAQSLLATYIKLNVARHQQGQPLSLPVHVADAFRAVLLDEKIDPALAAEILTLPSVNE
                     MAELFDIIDPIAIAEVREALTRTLATELADELLAIYNANYQSEYRVEHEDIAKRTLRN
                     ACLRFLAFGETHLADVLVSKQYHEANNMTDALAALSAAVAAQLPCRDALMQEYDDKWH
                     QDGLVMDKWFILQATSPAANVLETVRGLLQHRSFTMSNPNRIRSLIGAFAGSNPAAFH
                     AEDGSGYQFLVEMLTDLNSRNPQVASRLIEPLIRLKRYDAKRQEKMRAALEQLKGLEN
                     LSGDLYEKITKALA"
     gene            7431..8633
                     /gene="pncB"
                     /locus_tag="RHX21_004065"
     CDS             7431..8633
                     /gene="pncB"
                     /locus_tag="RHX21_004065"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706850.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HDV1989182.1"
                     /translation="MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVHVAAEFRCRGD
                     DLLGIYADAIREQIQAMQHLRLQDDEYQWLSALPFFKADYLNWLREFRFNPEQVTVSN
                     DNGKLDIRLSGPWREVILWEVPLLAVISEMVHRYRSPQADVAQALDTLESKLVDFSAL
                     TAGLDMSRFHLMDFGTRRRFSREVQETIVKRLQQESWFVGTSNYDLARRLSLTPMGTQ
                     AHEWFQAHQQISPDLANSQRAALAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASR
                     YQGLRHDSGDPVEWGEKAIAHYEKLGIDPQSKTLVFSDNLDLRKAVELYRHFSSRVQL
                     SFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFD
                     LPHIKKAS"
     gene            8802..10202
                     /gene="asnS"
                     /locus_tag="RHX21_004066"
     CDS             8802..10202
                     /gene="asnS"
                     /locus_tag="RHX21_004066"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HDV1989183.1"
                     /translation="MSVVPVADVLQGRVAVDSEVTVRGWVRTRRDSKAGISFLAVYDG
                     SCFDPVQAVINNSLPNYNEDVLRLTTGCSVIVTGKVVASPGQGQQFEIQASKVEVAGW
                     VEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFNEQGFFWV
                     STPLITASDTEGAGEMFRVSTLDLENLPRNDQGKVDFDKDFFGKESFLTVSGQLNGET
                     YACALSKIYTFGPTFRAENSNTSRHLAEFWMLEPEVAFANLNDIAGLAEAMLKYVFKA
                     VLEERADDMKFFAERVDKDAVSRLERFIEADFAQVDYTDAVTILENCGRKFENPVYWG
                     VDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIG
                     GSQREERLDVLDERMLEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLIAYVTGVQN
                     VRDVIPFPRTPRNASF"
BASE COUNT         2377 a         2711 c         2816 g         2588 t
ORIGIN      
        1 agaaaaagat acacaaaatt tatatttggc attttcttgt ctctccgaca gactgaccga
       61 attgttatca atgttaacaa aaaaagaaca attggttata aggagagagt atgcgtgtca
      121 tcaccctggc gggtagtcct cgctttcctt ctcgctccag ctccttgctg gaatatgcgc
      181 gggaaaaact aaatggcctc gatgtagagg tttatcactg gaatctgcaa aacttcgccc
      241 cggaagatct gctttatgct cgtttcgata gtccggcact caagaccttc accgaacagc
      301 tgcaacaggc tgatggactg atagtcgcta cacctgtgta taaagccgcc tattccggcg
      361 cgctgaaaac cctgctcgac ctgctgccag agcgcgcttt gcaaggcaaa gtggtgctac
      421 cgctggcgac gggcggtacc gtggcccatc tgctggcggt cgattatgcc cttaaaccag
      481 ttttaagcgc actgaaagcc caggagatcc tgcacggcgt gtttgccgat gactcacaag
      541 tcattgatta ccatcacaga ccccagttca cgccaaatct gcaaacccgt cttgataccg
      601 cgctagaaac tttctggcag gcattgcacc gccgcgatgt tcaggttcct gaccttctgt
      661 ctctgcgagg taatgtccat gcgtaacatc attaaactgg cgctggcggg attgcttagc
      721 gtctctactt ttgcggttgc tgcagaatcc tcgcctgaag cgttacgtat aggctatcag
      781 aaaggcagta ttggtatggt gctggcaaaa agccaccagt tactggaaaa acgctatccg
      841 caatcaaaaa tctcctgggt ggagttcccc gcgggtccgc aaatgttgga agcgttaaac
      901 gttggcagta ttgatctcgg cagtaccggg gatattccgc caatctttgc ccaggctgcc
      961 ggggctgatt tggtatatgt gggcgtcgag ccaccgaagc ccaaagccga agtgattctg
     1021 gtggcagaaa acagcccgat caaaaccgta gccgatctta aaggtcacaa agttgccttt
     1081 cagaaaggtt ccagttcaca caacctttta ctgcgtgcac tgcgtcaggc cggacttaag
     1141 tttaccgata tacaacccac ttacctgaca cctgccgatg cccgcgccgc gttccagcaa
     1201 ggtaacgttg acgcctgggc tatctgggat ccctactact ccgctgcgtt attacagggc
     1261 ggcgtgcggg tgttgaaaga cggcaccgat ctcaatcaaa ccggatcgtt ttatctggca
     1321 gctcgcccct atgcagaaaa aaacggcgct tttattcagg gcgtactggc aacctttagt
     1381 gaggccgatg cgttaacccg cagccagcgc gagcaaagca tcgctttact ggcaaaaacg
     1441 atgggcttac cggcaccggt gattgcctct tacttagatc atcgccctcc taccaccatc
     1501 aaaccggtta acgccgagat tgccgcctta cagcagcaaa cggcagatct gttttatgaa
     1561 aatcgtctgg tgccgaaaaa agtcgatatt cgccagcgca tctggcagcc cactcaactg
     1621 gaaggaaaac aattatgagt ctgaatatgt tctggttttt accgacccac ggtgacgggc
     1681 actatctggg aacggaagaa ggttcacgcc cggttgatca cggttatctg caacaaattg
     1741 cgcaagcggc ggatcgtctg ggctataccg gtgtgctgat cccaacgggg cgatcgtgtg
     1801 aagatgcgtg gctggtggcg gcgtcgatga tcccggtgac gcagcggctg aagtttcttg
     1861 tcgccctgcg ccccagcgta acctcaccta ccgttgccgc tcgccaggcc gccacgcttg
     1921 accgtctctc aaatggtcgt gcgttgttta atctggtcac aggcagcgat ccacaagagc
     1981 tggcaggcga cggcgtgttc cttgatcata gcgagcgcta cgaagcctcg gcggaattta
     2041 cccaggtctg gcggcgctta ttgctggggg aaaccgtcaa tttcaacggt aaacatattc
     2101 atgtgcgcgg agcaaaactg ctcttcccgc cgattcaaca gccttatcct ccgctttact
     2161 ttggcggatc gtcagacgtc gcccaggagc tggcggcaga acaagttgat ctctacctca
     2221 cctggggcga accgccagaa ctagtaaaag agaagatcga acaagtgcgg gcgaaagctg
     2281 ccgcgcatgg acgcaaaatt cgtttcggta ttcgtctgca tgtgattgtt cgtgaaacta
     2341 acgacgaagc gtggcaggcc gccgagcggt taatctcgca tcttgatgat gaaactatcg
     2401 ccaaagcaca ggccgcattc gcccggacgg attccgtagg acaacagcga atggcggcgt
     2461 tacataacgg caagcgcgac aatctggaga tcagccccaa tttatgggcg ggcgttggct
     2521 tagtgcgcgg cggtgccgga acggcgctgg tgggcgatgg tcctacggtc gctgcgcgaa
     2581 tcaacgaata cgccgcgctt ggcatcgaca gctttgtgct ttcgggctat ccgcatctgg
     2641 aagaagcgta tcgggtcggc gagttgctgt tcccacatct ggatgtcgcc attccggaaa
     2701 ttccccagcc gcagccgctg aatccgcaag gcgaagcggt ggcgaatgat tttatccccc
     2761 gtaaagtcgc gcaaagttaa ggaagaaata atggcaacgc cagtgaagaa gtggttattg
     2821 cgcgttgccc cctggttttt accggtgggc atcgtggcgg tgtggcaact ggcctcctca
     2881 gttggctggc tgtcgacgcg tattttgccc tcaccggaag gggtggtgac ggcgttctgg
     2941 acgctctccg ccagcggcga actgtggcag catctggcga tcagttcctg gcgggcgctg
     3001 attggctttt caattggcgg atcgctgggg ttgattttgg gactgattag cgggctatct
     3061 cgctggggag aacggctgct ggatacctca attcagatgt tgcgcaacgt accgcatctg
     3121 gcgctgatcc cgctggtgat tttgtggttt ggcattgatg aatccgcaaa aatctttctg
     3181 gtggcgctcg gcacgctatt ccccatttat atcaacacct ggcatggcat ccgtaatatc
     3241 gatcgcggtc tggtggaaat ggcgcgtagc tatggattat ccggcatacc gctgtttatc
     3301 catgtgatcc tgcctggtgc cctgccctca attatggtcg gcgtgcgttt tgcgttgggc
     3361 ctgatgtggc tgacgctgat tgttgccgaa accatttctg ccaattcagg cattggttat
     3421 ctggcgatga atgcgcggga gtttttgcaa acggacgtgg tggtagtcgc tattattctt
     3481 tacgccctgc tcggcaaact tgctgacgtc agcgcgcagc tgttagagcg cctctggttg
     3541 cgctggaacc cggcttatca tttgaaggag gccacggtat gaatactgct cgtctgaacc
     3601 agggcacacc attgttgctc aatgcagtaa gcaaacatta cgcggaaaat atcgtcctga
     3661 accaactgga tttacatatt ccggcaggtc agtttgtggc ggtggtgggc cgcagcggtg
     3721 gtggcaaaag taccctgctg cgcctgctgg caggtctgga aacgccaacc gcaggcgatg
     3781 tgttagcggg caccacaccg ctggctgaga ttcaggaaga cacgcgaatg atgtttcagg
     3841 atgcgcgtct gctgccgtgg aaatcggtga ttgataacgt tgggttaggc cttaaaggcc
     3901 agtggcgcga tgccgcgcgt cgggcgttgg ctgcagtagg actggagaat cgcgccgggg
     3961 aatggcctgc cgcactttct ggcgggcaga aacagcgtgt ggcgctggca agagcgttga
     4021 ttcatcgacc gggtttattg ttgcttgatg aaccgctcgg ggcgctggac gccttaacgc
     4081 gactcgagat gcaggatttg attgtgtcac tttggcagca gcacggcttt accgtactgt
     4141 tggtgacgca tgatgtgagc gaagcggtag caatggctga ccgggtgctg ttaattgaag
     4201 agggaaaaat tggtctggat ttgacggtgg atatccctcg tccgcgccgg ttagggtcgg
     4261 tgcgattagc ggagctggaa gcggaagtat tgcaacgggt aatgcggcgt gggcattctg
     4321 aacaactgat tcggcgtcat ggttaatatg ccggatgtgg cgcacaaaac cagcattttc
     4381 aacggactag taggcctgat aagacacgtc aagcatcgca tcaggcagtt gggcacggct
     4441 gccggatgcg gcgtgaacgc cttatccagc ctacaaaacc agcaatttca acggagttgt
     4501 aggcctgata agacgcgtca agcgtcgcat caggcatttt ggctcaaaag tatcaagcca
     4561 gtgctttggt gatcttctcg tacagatcgc cagagagatt ttccagccct ttcaactgtt
     4621 ccagcgccgc gcgcattttc tcctgacgtt tggcatcata acgtttcagg cgaatcagcg
     4681 gttcaatcag acgtgaagct acctgcgggt tacggctgtt gaggtcggta agcatttcca
     4741 ccaggaactg gtaaccgctg ccatcttcgg catggaacgc tgccgggttg ctgcccgcaa
     4801 acgcaccaat caacgaacga atacggttcg ggttgctcat ggtaaatgag cgatgctgca
     4861 acagaccacg caccgtctcc agcacattcg ccgccgggct ggtggcttgc aggataaacc
     4921 atttatccat caccagaccg tcctgatgcc acttatcgtc gtactcctgc atcagcgcgt
     4981 cacggcaagg cagctgtgca gcaaccgccg cagaaagcgc tgccagcgca tcggtcatat
     5041 tgtttgcttc atggtattgc ttgctcacca gcacgtcagc cagatgcgtt tcaccaaaag
     5101 caaggaagcg caggcaggca ttacgcagag tgcgttttgc aatatcttca tgctcaacac
     5161 ggtactcgct ctggtaattc gcgttgtaaa tagccagcag ctcatccgcc agttcagtcg
     5221 ccagagtacg agtgagtgct tcgcgtactt cggcaatagc aatcgggtcg atgatatcga
     5281 acagttcagc catttcattg acagaaggca gcgtcaggat ttctgccgcc agcgccggat
     5341 caatcttctc atcgagcagc accgcgcgga aagcgtcagc cacatgtacc ggcagagaca
     5401 gcggctgccc ttgctgatga cgggcgacgt tcagcttgat gtaggttgcc agcaaacttt
     5461 gcgccgcatc ccaacgggag aaatcattac gcgcatgacg catcaggaag gtcagttgct
     5521 gatcgctcca cttatattcc agtttcactg gcgcagagaa ttcgcacagc agcgcaggca
     5581 ccggctggaa gtagacatta tcaaaaacaa aggtctgttc cgcctgggtg acgttcagca
     5641 cggaattcac cggatgaccg cctttctgca acgggatcac tttgccttcg ttgtcataca
     5701 attcgatggc aaatggaata tgcagcggct gtttttctgc ctgatccggc gtggctggcg
     5761 tgcgctggct gatggtcagg gtgtactgct cggtttccgg attgtagtcg tctttgacgg
     5821 tcacaatcgg cgtgccggac tggctgtacc aacggcggaa atgggagaga tcgacattcg
     5881 acgcatcttc catcgcctgc acaaagtcgt cgcaggttgc cgcgctgcca tcatggcgct
     5941 cgaaatagag ttgcatccct ttctggaagt tttcttcgcc cagcagggtg tggatcatgc
     6001 gaatcacttc cgcgcccttc tcgtaaacgg tcagggtgta gaagttgttc atctcaatga
     6061 ccatatccgg gcggatcggg tgcgccatcg ggctggcgtc ttccgcaaac tgcaatccgc
     6121 gcatggtgcg cacattattg atacggttta ccgcgcggga accaaggtca gagctgaatt
     6181 cctgatcgcg gaagacggtt aaaccttctt tcaggctgag ctggaaccag tcgcggcagg
     6241 tcactcggtt accggtccag ttatggaaat attcatggcc gataacgcgt tcaatatcga
     6301 gataatcttt gtcggtggcg gtgtcggtgc gggccaacac atatttggag ttaaagatat
     6361 tcagcccctt attctccatt gcgcccatat tgaagaaatc caccgcgacg atcatataga
     6421 tgtcgaggtc atactccagg ccaaagcgtt cttcatccca tttcatggag tttttcagcg
     6481 aggtcatcgc ccacggcgcg cgatcaaggt tgccgcgatc gacgtacagc tccagtgcta
     6541 cttcgcgacc agaacgcgtg gtaaaggtat cgcgcagtac atcaaagtcg cctgccacca
     6601 gcgcaaacag gtagcacggt ttcgggaacg ggtcctgcca ctgtacccaa tggcgtccgt
     6661 tttcgagttc gccttgcgca acgcggttac cattggaaag caggaaggga tatttgattt
     6721 tatcggcaat aattttggtg gtaaaacgcg ccagcacgtc cgggcggtcg agataatacg
     6781 taatatggcg gaaaccttcg gcttcacact gggtgcaaag cgcatcgcct gactgataaa
     6841 gcccttccag cgccgtattc gccgccgggc ttatttcatt aatgatctta agcgtaaaac
     6901 gctccggcaa attactgatg accagtgcgc cctcttcttc tttccaggcg gtccacggct
     6961 catcattaat atgaacagaa accagtttga ggtcttcgcc gttgagacga agcggagcat
     7021 ctgatgcacc atgacggaca gcctggctga ccgcggtaac gaccgtcttt tgcgcgtcga
     7081 ggtcaaaggt caagtcaata tcagtaatct ggtaatccgg cgcacgataa tcgtgacggt
     7141 atttggcttg tggctgttga gtcataaata acctttagca tcttttatag agtctggtgt
     7201 tcagtctatt cctgttgcgt aaatcgcgct atgcagaatc ttcatctttt caggtacaaa
     7261 cgcctttatt gctacatttt tataacatac accgcgtaat gccatcgacc agaaaggtgg
     7321 catatggtgt gatcggggtt caataaattg cgaaacaagg tatactccag cagttcctga
     7381 agatgtttat tgtactaaac gctcctgtac gaggacgcta ctgcgcacct atgacacaat
     7441 tcgcttctcc tgttctgcac tcgttgctgg atacagatgc ttataagttg catatgcagc
     7501 aagccgtgtt tcatcactat tacgatgtgc atgtcgcggc ggagtttcgt tgccgaggtg
     7561 acgatctgct gggtatttat gccgatgcta ttcgtgaaca gattcaggcg atgcagcacc
     7621 tgcgcctgca ggatgatgaa tatcagtggc tctctgctct gcctttcttt aaggccgact
     7681 atcttaactg gttacgcgag ttccgcttta acccggaaca agtcaccgta tccaacgata
     7741 atggcaagct ggatattcgt ttaagcggcc cgtggcgtga agtcatcctc tgggaagttc
     7801 ctttgctggc ggttatcagt gaaatggtac atcgctatcg ctcaccgcag gccgacgttg
     7861 cgcaagccct cgacacgctg gaaagcaaat tagtcgactt ctcggcgtta accgccggcc
     7921 ttgatatgtc gcgcttccat cttatggatt ttggcacccg tcgccgtttt tctcgcgaag
     7981 tacaagaaac catcgttaag cgtctgcaac aggaatcctg gttcgtgggc accagcaact
     8041 acgatctggc gcgtcggctt tccctcacgc cgatgggaac acaggcacac gaatggttcc
     8101 aggcacatca gcaaatcagc ccggatctag ccaacagcca gcgagctgca cttgctgcct
     8161 ggctggaaga atatcccgac caacttggca ttgcattaac cgactgcatc actatggatg
     8221 ctttcctgcg tgatttcggt gtcgagttcg ccagtcgcta tcagggcctg cgtcatgact
     8281 ctggcgaccc ggttgaatgg ggtgaaaaag ccattgcaca ttatgaaaag ctgggaattg
     8341 atccacagag taaaactctg gttttctctg acaatctgga tttacgcaaa gcggttgagc
     8401 tataccgcca cttctcttcc cgcgtgcaat taagttttgg tattgggact cgcctgacct
     8461 gcgatatccc ccaggtaaaa cccctgaata ttgtgattaa gttggttgag tgtaacggta
     8521 aaccggtggc gaaactttct gacagccctg gcaaaactat ctgccacgat aaagcgtttg
     8581 ttcgggcgct gcgcaaagcg ttcgaccttc cgcatattaa aaaagccagt taatatcatc
     8641 agggagctaa tcggctccct ttttttacct ttaattccga aatctttcgc tgcatttgcg
     8701 aattctgctt gtctgattgc agatgccagg taacataggt atccccccat ttacgggtgg
     8761 acaagtgttt attttttccg actattaaca gagagaatat tatgagcgtt gtgcctgtag
     8821 ccgacgtact ccagggccgc gtagccgttg acagcgaagt caccgtacgc ggatgggtac
     8881 gtacccgccg agattcaaaa gctggcatct ccttcctcgc cgtttatgac ggttcctgct
     8941 ttgatcctgt acaggctgtc atcaataatt ctctgcccaa ttacaatgaa gacgtcctgc
     9001 gtctgaccac cggctgctcg gtcattgtga cgggtaaagt cgtggcgtcg ccgggccagg
     9061 ggcaacaatt tgaaattcag gccagcaaag ttgaagttgc tggttgggtt gaagatccag
     9121 acacttaccc gatggcggca aaacgccaca gcattgagta tctgcgtgaa gtcgctcacc
     9181 tgcgtccgcg cacaaacctg attggtgccg tcgcgcgcgt tcgccatacg ctggcgcagg
     9241 cgctgcatcg cttctttaac gagcagggat tcttctgggt ttcaacgcca ctgattaccg
     9301 catctgatac cgaaggtgca ggcgaaatgt tccgcgtttc tacgctggat ctggaaaacc
     9361 tgccgcgtaa cgatcagggc aaagtggatt tcgacaaaga cttctttggt aaagagtctt
     9421 tcctgaccgt atctggccag ttgaacggcg aaacctacgc ttgcgcatta tccaaaattt
     9481 ataccttcgg cccgactttc cgtgctgaaa actccaacac cagccgtcac ctggcggaat
     9541 tctggatgct ggagccggaa gtggcgtttg ctaacctgaa cgatatcgcg ggtctggctg
     9601 aagccatgct gaaatatgtc ttcaaagcgg ttctcgaaga acgcgcagac gacatgaaat
     9661 tcttcgctga acgcgtagat aaagatgccg tttcacgtct ggaacgcttc attgaggccg
     9721 atttcgcgca ggtggattac accgacgcag tgaccattct cgaaaactgc ggcaggaagt
     9781 ttgaaaaccc ggtttactgg ggcgtcgatc tctcttctga gcatgagcgt tatctggcgg
     9841 aagaacactt taaagcaccg gtagtggtta aaaactatcc gaaagatatt aaagcgttct
     9901 atatgcgcct caacgaagac ggtaaaaccg ttgcggctat ggacgttctg gctccgggca
     9961 tcggtgagat cattggtggc tcccagcgtg aagaacgtct ggacgttctg gacgagcgta
    10021 tgctggaaat gggcctgaat aaagaagatt actggtggta tcgcgatctg cgtcgctacg
    10081 gtactgttcc gcattcaggt ttcggtcttg gttttgaacg cctgattgct tacgtaactg
    10141 gcgtgcaaaa cgtgcgtgat gtgattccgt tcccacgtac tccgcgcaac gccagcttct
    10201 gattttcttc ctcaaagagc cagcgcctgc tggctctttt ttatcctttc tgtcaagtta
    10261 tctgtttgtt aagtcaagca atctatttgc aaccccgcca taacgatcat cctgttacgg
    10321 aatattacat tgcaacattt acgcacaaaa aataacccgc attcttattg cggattagtt
    10381 ttttcttagc tgatagcaca attttcatac tattttttgg cattctggat gtctgaaaga
    10441 ggattttgtg ccaggtcgat aaagtttcca tcagaaacaa aatttccgtt ta
//
LOCUS       DAPGUL010000145        10329 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.148, whole genome shotgun sequence.
ACCESSION   DAPGUL010000145 DAPGUL010000000
VERSION     DAPGUL010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10329)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10329)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10329
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.148"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(228..2801)
                     /gene="clpB"
                     /locus_tag="RHX21_004067"
     CDS             complement(228..2801)
                     /gene="clpB"
                     /locus_tag="RHX21_004067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002461515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HDV1989184.1"
                     /translation="MRLDRLTNKFQLALADAQSLALGHDNQFIEPLHLMSALLNQEGG
                     SVSPLLTSAGINAGQLRTDINQALNRLPQVEGTGGDVQPSQDLVRVLNLCDKLAQKRG
                     DNFISSELFVLAALESRGTLADILKAAGATTANITQAIEQMRGGESVNDQGAEDQRQA
                     LKKYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEG
                     LAQRIINGEVPEGLKGRRVLALDMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVILF
                     IDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYRQYIEKDAALERRFQ
                     KVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAID
                     LIDEAASSIRMQIDSKPEELDRLDRRIIQLKLEQQALMKESDEASKKRLDMLNEELSD
                     KERQYSELEEEWKAEKASLSGTQTIKAELEQAKIAIEQARRVGDLARMSELQYGKIPE
                     LEKQLEAATQLEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMMESEREKLLRMEQEL
                     HHRVIGQNEAVDAVSNAIRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKALANFMFD
                     SDEAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKA
                     HPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLIQERFGELDYAHMKEL
                     VLGVVSHNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLKRLYKRLEERGYEIHISDE
                     ALKLLSENGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKVIRLEVNEDRIVAV
                     Q"
     gene            complement(2931..3662)
                     /gene="pgeF"
                     /locus_tag="RHX21_004068"
     CDS             complement(2931..3662)
                     /gene="pgeF"
                     /locus_tag="RHX21_004068"
                     /EC_number="1.10.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphenol oxidase"
                     /protein_id="HDV1989185.1"
                     /translation="MSKLIVPQWPLPKGVAACSSTRIGGVSLPPYDSLNLGAHCGDNP
                     DHVEENRKRLFAAGNLPSKPVWLEQVHGKDVLKLTGEPYASKRADASYSNTPGTVCAV
                     MTADCLPVLFCNRVGTEVAAAHAGWRGLCAGVLEETVSCFADNPENILAWLGPAIGPR
                     AFEVGVEVREAFMAVDAKASAAFIQHGDKYLADIYQLARQRLANVGVEQIFGGDRCTY
                     TENETFFSYRRDKTTGRMASFIWLI"
     gene            complement(3659..4639)
                     /gene="rluD"
                     /locus_tag="RHX21_004069"
     CDS             complement(3659..4639)
                     /gene="rluD"
                     /locus_tag="RHX21_004069"
                     /EC_number="5.4.99.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017383977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(1911/1915/1917) synthase
                     RluD"
                     /protein_id="HDV1989186.1"
                     /translation="MAQRVQLTATVSENQLGQRLDQALAEMFPDYSRSRIKEWILDQR
                     VLVNGKVCDKPKEKVLGGEQVAINAEIEEEARFEPQDIPLDIVYEDEDIIVINKPRDL
                     VVHPGAGNPDGTVLNALLHYYPPIADVPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVE
                     SLQRREITREYEAVAIGHMTAGGTVDEPISRHPTKRTHMAVHPMGKPAVTHYRIMEHF
                     RVHTRLRLRLETGRTHQIRVHMAHITHPLVGDPVYGGRPRPPKGASEAFISMLRKFDR
                     QALHATMLRLYHPISGIEMEWHAPIPQDMVELIEVMRADFEEHKDEVDWL"
     gene            4774..5511
                     /gene="bamD"
                     /locus_tag="RHX21_004070"
     CDS             4774..5511
                     /gene="bamD"
                     /locus_tag="RHX21_004070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamD"
                     /protein_id="HDV1989187.1"
                     /translation="MTRMKYLVAAATLSLFLAGCSGSKEEVPDNPPNEIYATAQQKLQ
                     DGNWRQAITQLEALDNRYPFGPYSQQVQLDLIYAYYKNADLPLAQAAIDRFIRLNPTH
                     PNIDYVMYMRGLTNMALDDSALQGFFGVDRSDRDPQHARAAFSDFSKLVRGYPNSQYT
                     TDATKRLVFLKDRLAKYEYSVAEYYTERGAWVAVVNRVEGMLRDYPDTQATRDALPLM
                     ENAYRQMQMNAQAEKVAKIIAANSSNT"
     gene            5782..6123
                     /gene="raiA"
                     /locus_tag="RHX21_004071"
     CDS             5782..6123
                     /gene="raiA"
                     /locus_tag="RHX21_004071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDV1989188.1"
                     /translation="MTMNITSKQMEITPAIRQHVADRLAKLEKWQTHLINPHIILSKE
                     PQGFVADATINTPNGVLVASGKHEDMYTAINELINKLERQLNKLQHKGEARRAATSVK
                     DANFVEEVEEE"
     misc_feature    6226..6351
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01859"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Phe leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF01859"
     gene            6227..6274
                     /gene="pheL"
                     /locus_tag="RHX21_004072"
     CDS             6227..6274
                     /gene="pheL"
                     /locus_tag="RHX21_004072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pheA operon leader peptide PheL"
                     /protein_id="HDV1989189.1"
                     /translation="MKHTPFFFAFFFTFP"
     gene            6373..7533
                     /gene="pheA"
                     /locus_tag="RHX21_004073"
     CDS             6373..7533
                     /gene="pheA"
                     /locus_tag="RHX21_004073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chorismate mutase/prephenate
                     dehydratase"
                     /protein_id="HDV1989190.1"
                     /translation="MTSENPLLALREKISALDEKLLALLAERRELAVEVGKAKLLSHR
                     PVRDIDRERDLLERLITLGKAHHLDAHYITRLFQLIIEDSVLTQQALLQQHLNKINPH
                     SARIAFLGPKGSYSHLAARQYAARHFEQFIESGCAKFADIFNQVETGQADYAVVPIEN
                     TSSGAINDVYDLLQHTSLSIVGEMTLTIDHCLLVSGTTDLSTINTVYSHPQPFQQCSK
                     FLNRYPHWKIEYTESTSAAMEKVAQAKSPHVAALGSEAGGTLYGLQVLERIEANQQQN
                     FTRFVVLARKAINVSDQVPAKTTLLMATGQQAGALVEALLVLRNHNLIMTRLESRPIH
                     GNPWEEMFYLDIQANLESAEMQKALKELGEITRSMKVLGCYPSENVVPVDPT"
     gene            complement(7576..8697)
                     /gene="tyrA"
                     /locus_tag="RHX21_004074"
     CDS             complement(7576..8697)
                     /gene="tyrA"
                     /locus_tag="RHX21_004074"
                     /EC_number="1.3.1.12"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chorismate mutase/prephenate
                     dehydrogenase"
                     /protein_id="HDV1989191.1"
                     /translation="MVAELTALRDQIDEVDKALLNLLAKRLELVAEVGEVKSRFGLPI
                     YVPEREASMLASRRAEAEALGVPPDLIEDVLRRVMRESYSSENDKGFKTLCPSLRPVV
                     IVGGGGQMGRLFEKMLTLSGYQVRILEQHDWDRAADIVADAGMVIVSVPIHVTEQVIG
                     KLPPLPKDCILVDLASVKNGPLQAMLAAHDGPVLGLHPMFGPDSGSLAKQVVVWCDGR
                     KPEAYQWFLEQIQVWGARLHRISAVEHDQNMAFIQALRHFATFAYGLHLAEENVQLEQ
                     LLALSSPIYRLELAMVGRLFAQDPQLYADIIMSSERNLALIKRYYKRFGEAIELLEQG
                     DKQAFIDSFRKVEHWFGDYAQRFQSESRVLLRQANDNRQ"
     gene            complement(8708..9778)
                     /gene="aroF"
                     /locus_tag="RHX21_004075"
     CDS             complement(8708..9778)
                     /gene="aroF"
                     /locus_tag="RHX21_004075"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroF"
                     /protein_id="HDV1989192.1"
                     /translation="MQKDALNNVHITDEQVLMTPEQLKAAFPLSLQQEAQIADSRKTI
                     SDIIAGRDPRLLVVCGPCSIHDPETALEYARRFKALAAEVSDSLYLVMRVYFEKPRTT
                     VGWKGLINDPHMDGSFDVEAGLQIARKLLLELVNMGLPLATEALDPNSPQYLGDLFSW
                     SAIGARTTESQTHREMASGLSMPVGFKNGTDGSLATAINAMRAAAQPHRFVGINQAGQ
                     VALLQTQGNPDGHVILRGGKAPNYSPADVAQCEKEMEQAGLRPSLMVDCSHGNSNKDY
                     RRQPAVAESVVAQIKDGNRSIIGLMIESNIHEGNQSSEQPRSEMKYGVSVTDACISWE
                     MTDALLREIHQDLNGLLTARVA"
     gene            9988..>10329
                     /locus_tag="RHX21_004076"
     CDS             9988..>10329
                     /locus_tag="RHX21_004076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417093.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2799 domain-containing protein"
                     /protein_id="HDV1989193.1"
                     /translation="MMKKFIAPLLALLVSGCQIDPYTHAPTLTSTDWYDVGMEDAISG
                     SAIKDDDAFSDSQADRGLYLKGYAEGQKKTCQTDFTYARGLSGKSFPASCNNVENASQ
                     LHEVWQKGADEN"
BASE COUNT         2643 a         2731 c         2425 g         2530 t
ORIGIN      
        1 tttttgcttt ctctgccgga attctcagga gaaccccgct gacccggcgg cgtgtttgcc
       61 gttgttccgt gtcagtggtg gcgcattata gggagttatt ccggcctgac aagcgaaaaa
      121 tataaaaact ttatcgttcg ctcatttttc aggcaaaaca tcttaaatat agtcttttcc
      181 gtctaactta tagacaaaaa cgagccccga agggctcgtt ttatcattta ctggacggcg
      241 acaatccggt cttcattaac ttccaggcga atcactttac ccggaaccaa ttcaccagac
      301 agtatttgct gtgccagcgg gttttcgatc tgctgctgga tagcacgttt caaaggacgt
      361 gcaccataga ctggatcgta accgttctcg ctcagcagtt tcagcgcctc gtcagaaatg
      421 tggatttcat aaccacgttc ttccagacgt ttgtacagac gtttcaactg aatctgcgca
      481 atcgaggcaa tgtgctgttc acccagcgga tggaagacca ccacttcatc aatacggtta
      541 atgaattccg gacggaagtt atggcttacc acaccgagca ccagctcttt catgtgcgca
      601 taatccagtt caccgaagcg ttcctgaatc aaatcggaac cgaggttaga ggtcataatg
      661 acaaccgtat tacggaagtc gaccgttctc ccctgcccgt cagtcagacg accatcatcc
      721 agtacctgca acagaatgtt gaagacatcc ggatgcgctt tttccacttc atccagcagg
      781 atgacggaat acggacgacg acgcacagct tcggtcaggt agccaccttc ttcataaccg
      841 acatatcccg gaggcgcacc aaccagacga gacaccgagt gtttctccat aaactcggac
      901 atatcgatac ggaccatcgc ctcgtcgcta tcaaacataa agttcgccag cgccttacaa
      961 agctcagttt tccccacacc cgttgggccg aggaacagga atgaaccaat cgggcgattt
     1021 ggatccgcca accccgcacg gctacggcga atagcgttag ataccgcatc aaccgcttcg
     1081 ttctgaccaa tgacgcgatg gtgcagttct tgttccatac gcagcagttt ttcgcgctcg
     1141 ctttccatca tgcgagaaac cggaatcccc gtccaacgcg ccagcacttc agcaatttcg
     1201 gcatcggtca ctttattacg caacagacgc atagttttgc cttcgagctg cgttgcggct
     1261 tccagttgct tttccagttc cgggattttg ccgtattgca gttcagacat ccgcgccagg
     1321 tcccccacac ggcgagcctg ttcaatagcg attttcgcct gttccagttc cgctttaatg
     1381 gtctgcgtac cagaaagcga tgccttctct gctttccact cttcttctaa ctcggagtac
     1441 tgacgttctt tgtcgctcag ttcttcgttg agcatatcca ggcgtttttt actggcttca
     1501 tcagactctt tcattaacgc ctgttgttcc agtttgagct ggatgatacg acgatcgagt
     1561 cggtcgagtt cttctggttt tgagtcaatc tgcatacgaa tgctggatgc tgcttcatcg
     1621 atcaggtcga tggctttatc cggcagctga cggtcagcaa tgtagcgatg agacaacgtc
     1681 gccgctgcaa caattgccgg gtcagtaatt tgcacatggt ggtgcaattc gtaacgttct
     1741 ttcaggccac gcagaatcgc aatggtatct tcaacggaag gctcggcaac aaacactttc
     1801 tggaaacgac gttccagcgc agcatctttt tcaatgtact ggcgatattc gtcaagcgtc
     1861 gtggcaccta cgcagtgcaa ttcaccacgc gccagcgccg gtttcagcat gtttccggcg
     1921 tccattgcgc catcggcttt acccgcgccg accatggtat gtaattcgtc gataaacagg
     1981 atgacgttgc cttcctgttt ggcaagatcg ttaagcacgc cttttaaacg ttcttcaaac
     2041 tcaccgcgat atttcgcccc agccaccagc gcgcccatat ccagcgccag tacgcggcgg
     2101 cctttcaatc cttccggcac ttcgccgttg ataatacgct gcgccagacc ttcaacgatg
     2161 gcagttttac cgacgccggg ttcaccaatc agtaccgggt tatttttagt acgacgttgc
     2221 agcacctgaa tggtacggcg aatttcttca tcacgaccaa tcaccggatc gagtttgccc
     2281 tgttcggctc gttcggtaag gtcgatggta tattttttca aagcctgacg ttggtcttca
     2341 gcaccttgat cgttcacgct ttcacctcca cgcatttgtt caatcgcttg agtaatgttg
     2401 gcggtggtcg cccctgctgc tttcaggatg tcggccagcg tgccgcgaga ctcaagtgcc
     2461 gccagaacga acagttctga cgagataaag ttatcaccac gtttttgcgc cagcttgtcg
     2521 caaagattaa gaacgcgcac cagatcctgt gatggctgga catcaccacc agtaccttca
     2581 acctgcggta aacgatttaa tgcctgattg atatctgtgc gcaactggcc agcattgatg
     2641 ccagcggatg ttaataaagg actaaccgaa cccccttcct gattcagcag ggcgctcatt
     2701 aaatgaagtg gttcgataaa ttggttgtcg tgcccgagtg caagtgattg ggcatcggca
     2761 agagcaagct ggaatttatt agtaagacga tccagacgca taactcctcc cataacggat
     2821 caaagttgct actggagatt aaatgaggtc atccctcaat tattcaaggt tattgaccag
     2881 attaatgtga aaagaaaatc acgcgtaccg gatcgtcttg attctttagg ttatatcagc
     2941 caaatgaaac ttgccatacg accggtggtc ttgtcgcgac gataagagaa gaaagtctca
     3001 ttttccgtat atgtacaacg gtcgccgccg aaaatttgct caacacccac gttcgccaga
     3061 cgctgccggg caagctgata aatatccgcc agatacttat caccatgctg aatgaaagct
     3121 gcacttgctt tagcgtctac tgccataaac gcctcgcgaa cctccacccc cacttcgaac
     3181 gcgcgtggac caattgccgg ccctaaccag gcgagaatat tttccggatt atcagcaaaa
     3241 caggaaaccg tctcttccag cacgcctgcg cacagtccac gccagccagc atgagcggcg
     3301 gcgacttccg ttcccactcg attgcaaaac agcacaggga ggcagtcggc agtcatcact
     3361 gcgcaaaccg tgccaggcgt attgctataa gaggcatcag ctcgttttga ggcataaggt
     3421 tcgccagtaa gcttaagcac atctttgccg tgtacctgct caagccagac cggtttagaa
     3481 ggcaaattgc ccgcagcaaa aagtcgcttg cgattctcct caacgtgatc cgggttatcg
     3541 ccacaatggg caccgaggtt gagtgagtca tacgggggca agctcacgcc gccgatacga
     3601 gtagagctac aggccgcaac accttttggc agcggccact gcgggacaat cagcttactc
     3661 ataaccagtc cacttcatcc ttatgctctt cgaaatcggc gcgcatcacc tcaatcagct
     3721 ccaccatatc ttgtggaata ggcgcatgcc attccatttc gatgccggag atcgggtgat
     3781 aaagacgcag catggttgca tgaagcgcct ggcggtcaaa cttacgcagc atggagataa
     3841 atgcttccga agcacctttt ggcggacgcg gacggccacc ataaaccgga tcgcccacca
     3901 gcggatgagt gatatgggcc atatgcacgc ggatctggtg cgtacgtcca gtttccagac
     3961 gcaaccgcag acgcgtgtgc acacggaagt gttccatgat gcgatagtga gtcaccgccg
     4021 gtttgcccat cggatgcacc gccatgtgag tacgtttggt cgggtggcgg ctgatgggtt
     4081 catctactgt accgccagcg gtcatatgac caatcgccac cgcttcatac tcacgagtaa
     4141 tttcacgccg ttgcaaagat tcgactaaac gcgtctgagc cggaacggtt tttgccacaa
     4201 ccatcaggcc agtggtgtct ttatccagac gatggacgat gcccgcacgt ggtacatcgg
     4261 caatgggcgg atagtaatga agcaacgcat tcagtaccgt gccatccggg ttacccgcgc
     4321 caggatgtac caccaggtcg cgcggtttat taatgacgat gatatcttca tcttcataga
     4381 cgatatccag cgggatatcc tgcggttcaa aacgcgcttc ttcttcaatc tcagcattga
     4441 tggcaacctg ctcgccaccc aatacttttt ctttcggctt atcacaaact ttgccgttta
     4501 ccagcacgcg ctggtcgagg atccattctt ttattcgcga acgtgaataa tccgggaaca
     4561 tttcggccaa agcctgatct aagcgttgac cgagttggtt ttcggacacc gttgcagtga
     4621 gctgtactcg ttgtgccata tatactgctt cttcgtttat cgttggggtt ttacggcttt
     4681 gccgtttaat atagtgtgct attgtagctg gtcttaaccg ggagcaggaa cagagaatct
     4741 cccgtattac attttgagga aagtcaaaac gtcatgacgc gcatgaaata tctggtggca
     4801 gccgccacac taagcctgtt tttggcgggt tgctcggggt caaaggaaga agtacctgat
     4861 aatccgccaa atgaaattta cgcgactgca caacaaaagc tgcaggacgg taactggaga
     4921 caggcaataa cgcaactgga agcgttagat aatcgctatc cgtttggtcc gtattcgcag
     4981 caggtgcagc tggatctcat ctacgcctac tataaaaacg ccgatttgcc gttagcgcag
     5041 gctgccatcg atcgttttat tcgccttaac ccgacccatc cgaatatcga ttatgtcatg
     5101 tacatgcgtg gcctgaccaa tatggcgctg gatgacagtg cgctgcaagg gttctttggc
     5161 gttgaccgta gcgatcgcga tcctcaacat gcacgagctg cgtttagtga cttttccaaa
     5221 ctggtgcgcg gctatccaaa cagtcagtac accaccgatg ccaccaaacg tctggtattc
     5281 ctgaaagatc gtctggcgaa atatgaatac tccgtggccg agtactatac agaacgtggc
     5341 gcatgggttg ccgtcgttaa ccgcgtagaa ggaatgttgc gcgactaccc ggatacccag
     5401 gctacgcgtg atgcgctgcc gctgatggaa aatgcatacc gtcagatgca gatgaatgcg
     5461 caagctgaaa aagtagcgaa aatcatcgcc gcaaacagca gcaatacata acagaaacct
     5521 gaaatacaaa acggcagccc ttgagctgcc gtttttttat tctgttagtt gtgaaactga
     5581 agcgatttag tcactatcga tctcatcaaa tatggctcgc tttgagatat tcctcaagta
     5641 aaaaaacacc tcttcctgcg atttctcaca aaaaagattc gttgacaaaa agtgacaaaa
     5701 ttatgagatt cccatcacac attttgacat caggagcggt atgctgaatt caccaagacg
     5761 ggaagacaag aggtaaaatt tatgacaatg aacattacca gcaaacaaat ggaaattact
     5821 ccggccatcc gccaacatgt cgcagaccgt ctcgccaaac tggaaaaatg gcaaacacat
     5881 ctgattaatc cacatatcat tctgtccaaa gagccacaag ggtttgttgc tgacgccaca
     5941 atcaatacac ctaacggcgt tctggttgcc agtggtaaac atgaagatat gtacactgca
     6001 attaacgaat tgatcaacaa gctggaacgg cagctcaata aactgcagca caaaggcgaa
     6061 gcacgtcgtg ccgcaacatc ggtgaaagac gccaacttcg tcgaagaagt tgaagaagag
     6121 tagtccttta tattgagtgt atcgccaacg cgccttcggg cgcgtttttt gttgacagcg
     6181 tgaaaacagt acgggtactg tactaaagtc acttaaggaa acaaacatga aacacacacc
     6241 gtttttcttc gcattctttt ttaccttccc ctgaatggga ggcgtttcgt cgtgtgaaac
     6301 agaatgcgaa gacgaacaat aaggcctccc aaatcggggg gcctttttta ttgataacaa
     6361 aaaggcaaca ctatgacatc ggaaaacccg ttactggcgc tgcgagagaa aatcagcgcg
     6421 ctggatgaaa aattattagc attactggca gagcggcgcg aattggccgt cgaggtagga
     6481 aaagccaaac tgctctcgca tcgcccggta cgagatattg atcgtgaacg cgatttactg
     6541 gaaagattaa ttacgctcgg taaagcgcac catctggacg cccattacat tactcgcctg
     6601 ttccagctca tcattgaaga ttccgtatta actcagcagg ctttgctcca gcaacatctc
     6661 aataaaatta atccgcactc agcacgcatc gcttttctcg gccccaaagg ttcttattcc
     6721 catcttgcgg cgcgccagta tgctgcccgt cactttgagc aattcattga aagtggctgc
     6781 gccaaatttg ccgatatttt taatcaggtg gaaaccggcc aggccgacta tgccgtcgta
     6841 ccgattgaaa ataccagctc cggtgccata aacgacgttt acgatctgct gcaacatacc
     6901 agcttgtcga ttgttggcga gatgacgtta actatcgacc attgtttgtt ggtctccggc
     6961 acgactgatt tatccaccat taatacggtc tacagccatc cgcagccatt ccagcaatgc
     7021 agcaaattcc ttaatcgtta tcctcactgg aagattgaat ataccgaaag tacgtctgcg
     7081 gcaatggaaa aggttgcaca ggcaaaatca ccgcatgttg ctgcattggg aagcgaagct
     7141 ggcggcactt tgtacggttt gcaggtactg gagcgtattg aagcgaatca gcaacaaaac
     7201 ttcacccgat ttgtggtgtt ggcacgtaaa gccattaacg tgtctgacca ggttccggcg
     7261 aaaacgacgt tgttaatggc gaccgggcaa caagccggtg cgctggttga agcgttgctg
     7321 gtgctgcgca accacaatct gattatgacc cgtctggaat cacgcccgat tcacggtaat
     7381 ccatgggaag agatgtttta tctggatatt caggccaatc ttgaatcagc ggaaatgcaa
     7441 aaagcattga aagagttagg ggaaattacc cgttcaatga aggtattggg ctgttaccca
     7501 agtgagaacg tagtgcctgt tgatccaacc tgatgaaaag gtgccggatg atgtgaatca
     7561 tccggcactg gattattact ggcggttgtc attcgcctga cgcaataaca cgcggctttc
     7621 actctgaaaa cgctgtgcgt aatcgccgaa ccagtgctcc accttgcgga aactgtcaat
     7681 aaacgcctgc ttatcgccct gctccagcaa ctcaatcgcc tcgccgaaac gcttatagta
     7741 acgtttgatt aacgccagat tacgctctga cgacataata atgtcggcat aaagctgcgg
     7801 atcctgagca aacagtcgcc cgaccatcgc cagctcaagg cggtaaatcg gcgaagagag
     7861 cgccagaagt tgctcaagct gaacattttc ttctgccaga tgcagcccat aagcaaaagt
     7921 agcaaagtgg cgcagagcct gaataaacgc catattctga tcgtgctcga cagcgctaat
     7981 acgatgcagc cgagcgcccc agacctgaat ttgctccaga aaccattggt atgcttccgg
     8041 cttacgtcca tcacaccaga ccacaacttg ctttgccagg ctaccgctgt ccgggccgaa
     8101 catcgggtgt aaccccagta ccgggccatc gtgcgccgcc agcatggcct gtaatggtcc
     8161 atttttcact gatgccagat caaccagaat acaatctttc ggtaaaggcg gtaatttgcc
     8221 gataacttgc tcagtaacgt ggattggcac actaacaatc accattccgg catcggcaac
     8281 aatatcagcc gctcgatccc agtcatgttg ctccagaatc cgcacctgat aacccgagag
     8341 ggtcagcatc ttctcgaaca ggcgtcccat ctgaccgcca ccgccgacga taaccaccgg
     8401 acgcagtgac ggacaaagtg ttttaaatcc tttgtcgttt tcactggagt aagattcacg
     8461 catcacccga cgcaaaacat cctcaatcag atctggcggt acacccagag cttccgcctc
     8521 tgcacgacgc gaggccaaca tagatgcctc gcgctccgga acataaatag gcagtccaaa
     8581 gcggcttttc acctcgccca cttcagcaac cagttccaga cgcttagcta ataaattcag
     8641 cagcgcttta tcgacttcat caatttgatc gcgtaatgcg gtcaattcag caaccataat
     8701 aaacctctta agccacgcga gccgtcagca gcccgttcag atcctgatga atttcacgca
     8761 gcaaggcatc ggtcatttcc cagctaatgc aggcatcggt tacggataca ccgtatttca
     8821 tttcactgcg cggttgctcg gaagactgat tgccctcgtg gatattactt tcgatcatca
     8881 gaccaataat tgagcgattg ccatctttga tttgagcaac cacggattct gccaccgcag
     8941 gctgacggcg ataatcttta ttggaattac cgtggctgca atctaccatc agagacgggc
     9001 gcagtcccgc ctgttccatc tctttttcac attgcgcaac atccgcaggg ctatagttcg
     9061 gcgctttacc accgcgcagg atgacatgcc cgtccggatt cccctgagtt tgtagcaacg
     9121 caacctgccc tgcctggtta atgccaacaa aacggtgcgg ctgggcggcg gcgcgcatag
     9181 cgttaattgc tgttgccaga ctgccgtcgg tgccgttttt aaaaccaacc ggcatggaaa
     9241 gcccggaggc catttcacgg tgagtttgcg attccgttgt acgagcacca attgctgacc
     9301 agctaaacag atcgcccagg tattgcgggc tattcggatc taacgcttcc gtcgccagtg
     9361 gcagtcccat attcaccagc tcaagcagca atttacgcgc gatctgcagc ccggcttcta
     9421 catcaaaaga gccatccata tggggatcgt taattaaccc tttccagccg acagtggtac
     9481 ggggtttttc aaaatagacg cgcattacca gatagaggct atcgctgacc tctgcggcaa
     9541 gggctttaaa tcgacgagca tattccagag cagtttccgg atcatgaatg gaacaaggac
     9601 cacatactac cagcagacga ggatcgcgcc cggcgataat atctgaaatg gttttacgcg
     9661 agtcagcaat ctgggcttct tgttgcaggc tcaatggaaa agcggccttc agttgttccg
     9721 gagtcattaa aacctgttcg tcggtaatat gtacgttatt cagcgcgtct ttttgcatga
     9781 tggcgatcct gtttatgctc gtttgcgata gttgatcctc agcgaggatg acgtaacgat
     9841 aacacataaa gtaaagtttt caatccatat ttcgtacatt tttatttaca ctggcaattt
     9901 agtcgcgatt tcacccctta cttctgtata gataaattta cactcccttt gaaaacaatc
     9961 cgctatgctt tgaaaaagga gaaagaaatg atgaaaaagt ttatcgcccc cttgttggct
    10021 ttactggtta gcggatgtca gattgatcct tatactcacg cgccaacctt gaccagcacc
    10081 gactggtatg atgttggtat ggaagatgcg atatcgggca gcgccataaa agatgacgat
    10141 gcatttagcg attcacaggc ggatcgcggt ctatacctta aaggatatgc cgaaggacaa
    10201 aagaaaactt gccagaccga ttttacttat gcccgaggac tttccggtaa aagctttcct
    10261 gccagctgca acaatgttga aaatgccagc caactgcatg aagtatggca aaaaggggct
    10321 gatgaaaat
//
LOCUS       DAPGUL010000146        10320 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.149, whole genome shotgun sequence.
ACCESSION   DAPGUL010000146 DAPGUL010000000
VERSION     DAPGUL010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10320)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10320)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10320
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.149"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            28..408
                     /gene="crcB"
                     /locus_tag="RHX21_004077"
     CDS             28..408
                     /gene="crcB"
                     /locus_tag="RHX21_004077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001318207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HDV1989194.1"
                     /translation="MIKSLFAVIIGGSVGCTLRWLLSTRFNSLFPNLPPGTLVVNLLA
                     GLIIGTALAYFLRQPHLDPFWKLMITTGLCGGLSTFSTFSVEVFALLQAGNYIWALTS
                     VLVHVIGSLIMTALGFFIITILFA"
     gene            complement(788..1981)
                     /locus_tag="RHX21_004078"
     CDS             complement(788..1981)
                     /locus_tag="RHX21_004078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1989195.1"
                     /translation="MSSKIEDTPQKTLSCWPLAFSAGLLGIGQNGLLVVLPVLVIQTN
                     LSLSVWAALLMLGSMLFLPSSPWWGKQISLTGSKTVVLWALGGYGVSFTLLGLGSVLM
                     ATGAVTTAVGLGILIIARIVYGLTVSAMVPACQVWALQRAGEGNRMAALATISSGLSC
                     GRLFGPLCAAAMLVIHPLAPVWMLMAAPVWAVVMLLRLPGTPPQPTPERKSVSLKRDC
                     LPYLLCAMLLAAAMSMMQLGLSPALTRQFDTDTTTISQQVAWLLGLSAIAALIAQFVV
                     LRPQRLTPVALLLSAGVLMSSGLAIMLTEQLWLFYLGCAVLSFGAALATPAYQLLLND
                     KLADGAGAGWLAASHTLGYGLCALLVPLASKTGVSIALIVTALFAAVLFTIVSACIWH
                     YRTIK"
     gene            2117..3841
                     /gene="iucA"
                     /locus_tag="RHX21_004079"
     CDS             2117..3841
                     /gene="iucA"
                     /locus_tag="RHX21_004079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001314127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerobactin synthase IucA"
                     /protein_id="HDV1989196.1"
                     /translation="MILPSEKSATDVAAQCFLNALIRETKDWQLAEYPPDELIIPLDE
                     QKSLHFRVAYFSPTQHHRFAFPAHLVTASGSYPVDFTTLSRLIIDKLRHQLFLPVPLC
                     ETFHQRVLESYAHTQQTIDARHDWAILREKALNFGEAEQALLTGHAFHPAPKSHEPFN
                     RQEAERYLPDMAPHFPLRWFSVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDN
                     QWLFPLHPWQGEYLLQQVWCQALFAKGLIRDLGEAGTSWLPTTSSRSLYCATSRDMIK
                     FSLSVRLTNSVRTLSVKEVERGMRLARLAQTDGWQMLQARFPTFRVMQEDGWAGLRDL
                     NGNIMQESLFSLRENLLLEQPQSQTNVLVSLTQAAPDGGDSLLVSAVKRLSDRLGITV
                     QQAAHAWVDAYCQQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPVGFIYRDCQGSA
                     FMPHATEWLDTIDEAQAENIFTREQLLRYFPYYLLVNSTFAVTAALGAAGLDSEANLM
                     ARVRTLLAEVRDQVTHKTCLNYVLESPYWNVKGNFFCYLNDHNENTIVDPSVIYFDFA
                     NPLQAQEV"
     gene            3842..4789
                     /gene="iucB"
                     /locus_tag="RHX21_004080"
     CDS             3842..4789
                     /gene="iucB"
                     /locus_tag="RHX21_004080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(6)-hydroxylysine O-acetyltransferase"
                     /protein_id="HDV1989197.1"
                     /translation="MSGANIVHSGYGLRCEKLDKPLNLGWGLDNSAVLHWPGELPTGW
                     LCDALDQIFIAAPQLSAVVLPWSEWCEEPQALTLFGQVQSDIIHRSAFWQLPLWLSSP
                     ANRASGEMVFDAEREIYFPQRPPRPQGEVYRRYDPRIRRMLSFRIADPVSDAERFTRW
                     MNDPRVEYFWEQSGSLEVQIAYLERQLTSKHAFPLIGCFDDRPFSYFEIYWAAEDRIG
                     RHYSWQPFDRGLHLLVGEQQWRGAHYVQSWLRGVTHYLLLNEPRTQRTVLEPRTDNQR
                     LFRHLEPAGYRTIKEFDFPHKRSRMVMADRHHFFTEVGL"
     gene            4789..6531
                     /gene="iucC"
                     /locus_tag="RHX21_004081"
     CDS             4789..6531
                     /gene="iucC"
                     /locus_tag="RHX21_004081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerobactin synthase IucC"
                     /protein_id="HDV1989198.1"
                     /translation="MNHKDWDLVNRRLVAKMLSELEYEQVFHAESQGDDRYCINLPGA
                     QWRFIAERGIWGWLWIDAQTLRCADEPVLAQTLLMQLKQVLSMSDATVAEHMQDLYAT
                     LLGDLQLLKARRGLSASDLINLNADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEY
                     ANTFRLHWLAVKREHMIWRCDNEMDIHQLLTAAMDPQEFARFSQVWQENGLDHNWLPL
                     PVHPWQWQQKIATDFIADFAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPL
                     TIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYA
                     ALARAPYRYQEMLGVIWRENPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRSGLD
                     AETWLTQLFRVVVVPLYHLLCRYGVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLV
                     KEEFPEMDSLPQEVRDVTSRLSADYLIHDLQTGHFVTVLRFISPLMVRLGVPERRFYQ
                     LLAAVLSDYMKKHPQMSERFALFSLFRPQIIRVVLNPVKLTWPDLDGGSRMLPNYLED
                     LQNPLWLVTQEYES"
     gene            6528..7805
                     /gene="iucD"
                     /locus_tag="RHX21_004082"
     CDS             6528..7805
                     /gene="iucD"
                     /locus_tag="RHX21_004082"
                     /EC_number="1.14.13.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001354579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent L-lysine N(6)-monooxygenase"
                     /protein_id="HDV1989199.1"
                     /translation="MKKSVDFIGVGTGPFNLSIAALSHQIEELDCLFFDEHPHFSWHP
                     GMLVPDCHMQTVFLKDLVSAVAPTNPYSFVNYLVKHKKFYRFLTSRLRTVSREEFSDY
                     LRWAAEDMNNLYFSHTVENIDFDKKRRLFLVQTSQGEYFARNICLGTGKQPYLPPCVK
                     HMTQSCFHASEMNLRRPDLSGKRITVVGGGQSGADLFLNALRGEWGEAAEINWVSRRN
                     NFNALDEAAFADEYFTPEYISGFSGLEEDIRHQLLDEQKMTSDGITADSLLTIYRELY
                     HRFEVLRKPRNIRLLPSRSVTTLESSGPGWKLLMEHHLDQGRESLESDVVIFATGYRS
                     ALPQILPSLMPLITMHDKNTFKVRDDFTLEWSGPKENNIFVVNASMQTHGIAEPQLSL
                     MAWRSARILNRVMGRDLFDLSMPPALIQWRSGT"
     gene            7887..10088
                     /gene="iutA"
                     /locus_tag="RHX21_004083"
     CDS             7887..10088
                     /gene="iutA"
                     /locus_tag="RHX21_004083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004213924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric aerobactin receptor IutA"
                     /protein_id="HDV1989200.1"
                     /translation="MMISKKYTLWALNPLLLTMMAPAVAQQTDDETFVVSANRSNRTV
                     AEMAQTTWVIENAELEQQIQGGKELKDALAQLIPGLDVSSRSRTNYGMNVRGRPLVVL
                     VDGVRLNSSRTDSRQLDSIDPFNIDHIEVISGATSLYGGGSTGGLINIVTKKGQPETM
                     MEFEAGTKSGFSSSKDHDERIAGAVSGGNEHISGRLSVAYQKFGGWFDGNGDATLLDN
                     TQTGLQYSDRLDIMGTGTLNIDESRQLQLITQYYKSQGDDDYGLNLGKGFSAIRGTST
                     PFVSNGLNSDRIPGTERHLISLQYSDSAFLGQELVGQVYYRDESLRFYPFPTVNANKQ
                     VTAFSSSQQDTDQYGMKLTLNSKPMDGWQITWGLDADHERFTSNQMFFDLAQASASGG
                     LNNKKIYTTGRYPSYDITNLAAFLQSGYDINNLFTLNGGVRYQYTENKIDDFIGYAQQ
                     RQIAAGKATSADAIPGGSVDYDNFLFNAGLLMHITERQQAWLNFSQGVELPDPGKYYG
                     RGIYGAAVNGHLPLTKSVNVSDSKLEGVKVDSYELGWRFTGNNLRTQIAAYYSISDKS
                     VVANKDLTISVVDDKRRIYGVEGAVDYLIPDTDWSTGVNFNVLKTESKVNGTWQKYDV
                     KTASPSKATAYIGWAPDPWSLRVQSTTSFDVSDAQGYKVDGYTTVDLLGSYQLPVGTL
                     SFSIENLFDRDYTTVWGQRAPLYYSPGYGPASLYDYKGRGRTFGLNYSVLF"
BASE COUNT         2460 a         2713 c         2679 g         2468 t
ORIGIN      
        1 gataaaaaat tattttatga ggggtacatg attaaatcac tttttgccgt cattatcggc
       61 ggttctgttg gatgtactct gcgctggtta ctgtccacac gctttaacag tctttttcca
      121 aatctacctc caggtacact ggtggtgaac ctccttgccg ggttaattat tggtactgcg
      181 ttggcgtact ttttacgaca accacacctt gatccttttt ggaaattaat gataacaacg
      241 ggactttgtg gaggtctgag tactttctct acattttctg ttgaagtatt cgcattactc
      301 caggcgggaa attatatatg ggctttgacg tctgtacttg ttcacgtcat tggctccctc
      361 atcatgacag ctttaggctt ttttatcata accatacttt tcgcatgaga attcattaac
      421 gttacaggtt tatcaactaa tgtgacgctt aggatagaat ttcgctccat ggtatgcgtt
      481 tgcagtcatt acagtctcca tgacgactgt aatgactgca aacgcattac ctgacatatc
      541 agtataaaca atgaattaac ctcttggcgt attttttaca tcactggccc tcacccccca
      601 aaattctctc tgaaaaattg ttgcggttaa cgttgccaat gtatccaccc atttcagaag
      661 acgatctggt atcctggtgg catgctgcga tgtgcttcag gtgagtgcac tgggcggtca
      721 gcacaggcgg tttcgacagc gaaattgcac aggacgttat gccggctgtg agtacaacat
      781 catagcctta cttgattgta cggtaatgcc aaatacatgc agacactatg gtaaataata
      841 cagcggcaaa taatgccgtc acaatcagcg cgattgagac acctgttttc gacgccagtg
      901 gcaccaacaa tgcgcacagc ccatagccaa gtgtgtgact ggccgcaagc cagcccgcgc
      961 ctgcgccgtc ggccagctta tcattcagta aaagttgata agcgggtgtt gccagagcgg
     1021 ccccaaatga cagcactgca cagcccaggt aaaacaacca tagctgttca gtgagcatga
     1081 tagccagacc actactcatc aacaccccgg cactcaggag cagagccact ggagtcaggc
     1141 gctgtggacg gagtaccacg aactgcgcga taagcgcagc tattgcggac agccccaaca
     1201 accacgccac ctgttggcta atagtggtgg tatcagtatc gaactggcga gtaagggctg
     1261 gcgaaagtcc aagctgcatc atgctcattg ccgcagccag taacattgcg caaagcagat
     1321 aaggcaggca atcccgcttc aggctgacgc tcttgcgctc cggtgtgggc tgtggtggtg
     1381 tgccgggcaa ccgcagaagc atcaccacag cccacaccgg agctgccatc agcatccaca
     1441 ctggcgccag agggtgaatg accaacattg ccgccgcgca cagcggcccg aatagcctgc
     1501 cgcagctcag gccggagctg atggttgcca gagcggccat gcgattccct tctcccgctc
     1561 tctgcaatgc ccagacctga caggctggca ccattgctga cacggtcaga ccgtagacga
     1621 tccgggcgat gattaatatt cccaacccca ccgctgttgt tacggcaccg gtagccatca
     1681 gcacgcttcc cagcccaagc agggtaaagc ttacgccata tcctcccaga gcccacagca
     1741 ccacagtctt actgccagta agggaaattt gctttcccca ccatggggaa gatggcagaa
     1801 acagcattga gcccagcatc agcagggcag cccatacaga cagactcaga tttgtctgta
     1861 tgaccagaac agggagtaca accagcagac cgttctgtcc gataccgaga agaccggcac
     1921 tgaacgccag tggccagcag gacagggttt tttggggcgt atcttcgatc ttagatgaca
     1981 ttgtaatgtt tcaacaccat gtattaattg tgtttatttg taaaattaat ttttctgaca
     2041 ataacatttc tcattgataa tgagaatcat tattgacata attgttatta ttttactgtg
     2101 taggagctgt ttgattatga tcctgccctc tgaaaaatcc gccacagatg tggctgcgca
     2161 gtgcttcctg aatgccttga ttcgtgaaac caaagactgg caactggcgg aatacccgcc
     2221 agacgaattg attatcccgc tggacgaaca gaagtcgctc catttcagag tggcttattt
     2281 ctccccaacc cagcatcacc gctttgcatt tcctgctcat ctggtcacgg catcaggcag
     2341 ttatcctgtc gactttacca ctctctcccg gcttattatt gataagctcc ggcatcaact
     2401 ttttctgcca gttcccctct gcgaaacttt ccaccaacgc gtgctggaaa gctacgccca
     2461 tacgcaacag acaattgatg cccgccatga ctgggccatc ctgcgtgaaa aagcgttgaa
     2521 ttttggcgag gctgagcagg cactgctgac aggacacgct ttccaccctg cacctaagtc
     2581 tcatgaaccg tttaaccgcc aggaagctga acgatacctg cctgacatgg cacctcactt
     2641 cccgctgcgg tggttttcgg tggataaaac gcaaatcgct ggtgaaagtc tgcatcttaa
     2701 ccttcaacag cggttgacgc gatttgccgc agaaaatgcg ccccagttac tcaacgaatt
     2761 aagtgacaat caatggctgt tcccgctgca cccgtggcag ggagaatatc ttttgcagca
     2821 agtgtggtgc caggcacttt ttgctaaagg acttatcaga gacttaggcg aggccggcac
     2881 gtcgtggctg ccgaccacct cttcccgctc cctctactgt gctaccagcc gcgatatgat
     2941 caagttctcc ctgagcgttc ggctgaccaa ctccgtccgt actctgtctg tgaaagaggt
     3001 ggagcgagga atgcgcctgg cacgtctggc gcaaaccgac ggctggcaga tgctacaggc
     3061 ccgcttccct actttccggg taatgcagga ggacggctgg gccgggctgc gcgatcttaa
     3121 cggcaacatc atgcaggaaa gtttgttttc cctgcgtgaa aacctgctgc tggagcagcc
     3181 gcaaagccag accaacgttc tggtttccct gactcaggcc gcaccggatg gcggtgattc
     3241 gctgctggtt tcggcggtaa aacgcctgag cgatcgcctc ggtatcactg tgcaacaggc
     3301 cgcccacgca tgggtcgatg cttactgtca gcaggtgctg aagcctctgt ttacggctga
     3361 agcggattac ggcctggtgc tgctggcgca tcagcaaaat attcttgtgc agatgcttgg
     3421 ggatctgccg gtcggattta tttaccgtga ctgccagggc agcgcgttta tgcctcacgc
     3481 gacagagtgg ctcgatacca ttgacgaggc gcaggcggaa aatattttca cccgtgagca
     3541 gttgctgcgc tatttccctt attacctgct ggttaactcc acttttgccg taactgctgc
     3601 gctgggtgct gccgggctgg acagcgaagc gaatctgatg gctcgtgtac gaacattgct
     3661 ggctgaagtg cgtgaccagg tgactcataa aacctgtctc aactatgttc tggaaagtcc
     3721 gtactggaac gtaaaaggta actttttctg ttatctgaac gatcataacg agaacaccat
     3781 cgttgaccct tcggtgatct attttgattt cgctaacccg ctgcaggctc aggaggtctg
     3841 aatgtctggg gcaaacattg ttcacagcgg atatggactg cgctgtgaaa aactcgacaa
     3901 gcctctgaat cttggctggg ggctggacaa tagcgcggtg ttgcactggc ccggggagct
     3961 gccaacaggg tggctgtgcg acgcgctgga tcagatattt atcgccgcac cacaactttc
     4021 agcagtggtt cttccctggt ccgaatggtg tgaggagcca caggcgctga cgcttttcgg
     4081 acaggtacaa agcgacatta tccatcgttc cgctttctgg cagttaccgt tatggctgag
     4141 ttctccggca aaccgggcct ccggtgaaat ggtttttgat gcagagcgtg agatttattt
     4201 cccgcagcgc cccccccgtc cgcagggtga agtttatcgt cgttacgatc cacgcattcg
     4261 caggatgctg agtttccgca ttgccgatcc cgtttctgat gcagaacgtt tcactcgctg
     4321 gatgaacgat ccgcgcgttg agtatttctg ggagcaaagt ggctcactgg aggtacagat
     4381 cgcctatctg gaacgccagc tcaccagtaa acatgcattc ccgctgattg gttgtttcga
     4441 cgatcggccg ttcagttatt tcgaaatcta ctgggcggcg gaagaccgca ttggtcgcca
     4501 ctattcgtgg cagccctttg accgtggcct gcatctgctg gttggtgaac agcaatggcg
     4561 cggagcccac tatgtgcaaa gctggctgcg cggggtgaca cattacctgc tgctgaatga
     4621 gccacgtacg cagcgcacag tactggagcc acgcaccgat aaccagcgcc tgttccgcca
     4681 tcttgagcct gcgggatacc ggacaattaa agagttcgac ttcccacata aacgctcgcg
     4741 catggtgatg gcggatcgtc atcacttctt cacggaggtc ggtctgtaat gaatcacaaa
     4801 gactgggatt tggtcaaccg ccgcctggtg gcaaaaatgt tgtctgagct ggagtatgag
     4861 caggttttcc acgcggaatc tcagggcgat gaccgctact gcattaacct gccgggagca
     4921 caatggcgct tcatcgctga acgtggtatc tggggctggc tctggattga tgctcaaact
     4981 ctgcgctgcg cggacgagcc agtactggct cagacgctgc tgatgcagct aaagcaggta
     5041 ctgtcaatga gcgatgcaac cgttgctgag catatgcagg atttgtatgc cacgctgctg
     5101 ggcgacctgc aactactgaa agcccgtcgc gggctgagcg ccagtgacct gattaatctt
     5161 aatgccgacc gcctgcaatg cctgctgagc ggtcatccta aattcgtttt taataaaggt
     5221 cgccgtggct ggggtaaaga ggcgctggaa cgatatgcgc cagagtatgc caacaccttc
     5281 agactgcact ggctggcggt aaaacgtgaa catatgatct ggcgctgtga taacgagatg
     5341 gatattcatc agttgttgac ggccgcaatg gatccgcagg agtttgcccg cttcagtcag
     5401 gtctggcagg aaaacggact ggatcataac tggctgccgc tgccggtaca tccgtggcag
     5461 tggcagcaaa aaatcgctac cgacttcatc gctgattttg ccgaaggcag gatggtgtct
     5521 ctcggcgagt ttggcgacca gtggctcgcc cagcagtcgc tgcgtaccct gaccaacgcc
     5581 agtcgccggg gcgggctgga tatcaagctg ccgctgacca tctacaacac ctcatgctac
     5641 cgggggatcc ctggcagata catcgctgcc ggaccactgg cttcacgctg gctacaacag
     5701 gtttttgcga ccgacgccac cctagtgcaa agcggcgcag tgatacttgg tgaaccggct
     5761 gcaggctatg tctcccatga aggctatgcc gcgcttgccc gggctcccta tcgctaccag
     5821 gaaatgcttg gtgttatctg gcgggagaat ccgtgccgct ggctgaaacc ggatgaaagt
     5881 ccggttctga tggcaacact gatggagtgc gacgaaaaca atcagccgct ggcaggcgca
     5941 tatatagacc gctccgggct ggacgctgaa acctggctta cgcaactgtt ccgggtggtc
     6001 gtggttcctc tgtatcacct gctttgccgc tacggtgtcg cgcttattgc acatggacaa
     6061 aatataactc tcgccatgaa agagggggtt ccacagcgtg ttctgctgaa agacttccag
     6121 ggcgatatgc gactggtgaa agaagagttc cccgaaatgg actctttgcc tcaggaggtt
     6181 cgtgatgtta catcccgcct gagtgcggac tacttaatcc atgatttgca gacgggtcac
     6241 ttcgtgacag tactgcgttt tatttcgcca ctgatggttc gtcttggcgt acctgaaagg
     6301 cgattttatc aactgctggc agcagtgttg agtgattaca tgaaaaaaca tccacaaatg
     6361 tcagagcgtt ttgcgctttt ctcacttttc aggccacaaa tcattcgcgt ggtgctgaac
     6421 ccggtaaaac tgacctggcc tgatctggat ggcggcagcc gcatgctgcc gaattacctt
     6481 gaggatctgc aaaatccgct gtggctggta actcaggaat atgaatcatg aaaaaaagtg
     6541 tcgattttat tggtgtaggg acagggccat ttaatctcag cattgctgcg ttgtcacatc
     6601 agatcgaaga actggactgt ctcttctttg atgaacatcc tcatttttcc tggcatccgg
     6661 gtatgctggt accggattgt catatgcaga ccgtctttct gaaagatctg gtcagtgctg
     6721 ttgcacctac aaatccctac agttttgtta actatctggt gaagcacaaa aagttctatc
     6781 gcttccttac aagcagacta cgtacagtat cccgtgaaga gttttctgac tacctccgct
     6841 gggctgctga agatatgaat aacctgtatt tcagtcatac cgttgaaaac attgatttcg
     6901 ataaaaaacg tcgattgttt ctggtgcaaa ccagccaggg agaatatttt gcccgcaata
     6961 tctgccttgg tacaggaaaa caaccttatt taccaccctg tgtgaagcat atgacacaat
     7021 cctgtttcca tgccagtgaa atgaatcttc gtcggccgga ccttagtgga aaacggataa
     7081 ccgtggttgg tggaggacag agtggtgcag acctgttcct taatgcatta cgcggggaat
     7141 ggggagaagc ggcggaaata aactgggtct cccggcgtaa taattttaac gcactggatg
     7201 aggctgcttt tgctgatgag tattttacac ctgaatatat ttcaggcttc tccggactgg
     7261 aggaagatat tcgccatcag ttactggatg agcagaaaat gacatcggat ggcatcactg
     7321 ccgattcttt actgaccatt tatcgtgagt tgtaccaccg ttttgaagtt ctgagaaaac
     7381 caagaaatat ccgtctgcta cccagccgct cggtaacaac tctggaaagt agtggtcctg
     7441 gctggaagtt gctgatggag catcatctgg atcagggcag ggagagcctg gaaagtgatg
     7501 tggtgatttt cgccacaggt taccgttctg cgttgccaca aatacttccc tcactgatgc
     7561 ccctgatcac catgcacgat aagaacacct ttaaagtgcg tgatgacttc actctggaat
     7621 ggagtggccc gaaagagaac aacatcttcg tggtcaacgc cagtatgcaa acccatggca
     7681 tcgccgaacc ccagctcagc ctgatggcat ggagatctgc acgtattctt aatcgcgtaa
     7741 tgggacgtga tttattcgat ctcagtatgc cgcccgccct gattcagtgg cgcagcggca
     7801 cctagggaaa acgcagccgg aggctgcttc tttaactcgc tacacagcat ctttgggctg
     7861 attttttccg cccgtatgga ggaataatga tgataagcaa aaagtatacg ctttgggctc
     7921 tcaacccact gcttcttacc atgatggcgc cagcagtcgc tcaacaaacc gatgatgaaa
     7981 cgttcgtggt gtctgccaac cgcagcaatc gcaccgtagc ggagatggcg caaaccacct
     8041 gggttatcga aaacgccgaa ctggaacagc agattcaggg cggcaaagag cttaaagacg
     8101 cactggctca gctgatccct ggccttgacg tcagcagccg gagccgcacc aactacggta
     8161 tgaatgtgcg tggccgcccg ctggtcgtgc tggttgacgg cgtgcgtctc aactcttcac
     8221 gtaccgacag ccgacaactg gactctatag atccttttaa tatcgaccat attgaagtga
     8281 tctccggtgc gacgtccctg tacggcggcg gcagtaccgg tggcctgatc aacatcgtga
     8341 ccaaaaaagg ccagccggaa accatgatgg agtttgaggc tggcaccaaa agtggcttta
     8401 gcagcagtaa agatcacgat gaacgcattg ccggagctgt ctccggcgga aatgagcata
     8461 tctccggacg tctttccgtg gcatatcaga aatttggcgg ctggtttgac ggtaacggcg
     8521 atgccacctt gcttgataac acccagaccg gcctgcagta ctccgatcgg ctggacatca
     8581 tgggaactgg tacgctgaac atcgatgaat cccggcagct tcagttgatc acacagtact
     8641 ataaaagcca gggcgacgac gattacgggc ttaatctcgg gaaaggcttc tctgccatca
     8701 gagggaccag cacgccattc gtcagtaacg ggctgaattc cgaccgtatt cccggcactg
     8761 agcggcattt gatcagcctg cagtactctg acagcgcttt tctgggacag gagctggtcg
     8821 gtcaggttta ctaccgcgat gagtcgttgc gattctaccc gttcccgacg gtaaatgcga
     8881 acaaacaggt gacggctttc tcttcgtcac agcaggacac cgaccagtac ggcatgaaac
     8941 tgactctgaa cagcaaaccg atggacggct ggcaaatcac ctgggggctg gatgctgatc
     9001 atgagcgctt tacctccaac cagatgttct tcgacctggc tcaggcaagc gcttccggag
     9061 ggctgaacaa caagaagatt tacaccaccg ggcgctatcc gtcgtatgac atcaccaacc
     9121 tggcggcctt cctgcaatca ggctatgaca tcaataatct ctttaccctc aacggtggcg
     9181 tacgctatca gtacactgaa aacaagattg atgatttcat cggctacgcg cagcaacggc
     9241 agattgccgc cgggaaggct acatccgccg acgccattcc tggcggctca gtcgattacg
     9301 acaacttcct gttcaacgcc ggtctgctga tgcacatcac cgaacgccag caggcatggc
     9361 tcaacttctc ccagggcgtg gagctgccgg acccgggtaa atactatggt cgcggcatct
     9421 atggtgctgc agtgaacggc catcttcctc taacaaagag tgtgaacgtc agcgacagca
     9481 agctggaagg cgtgaaagtc gattcttatg agctgggctg gcgctttact ggcaataatc
     9541 tgcgtaccca aatcgcggcc tactattcga tttctgataa gagcgtggtg gcgaataaag
     9601 atctgaccat cagcgtggtg gacgacaaac gccgtattta cggcgtggaa ggtgcggtgg
     9661 actacctgat tcctgatact gactggagta ccggagtgaa cttcaacgtg ctgaaaactg
     9721 agtcgaaagt gaacggtacc tggcagaaat acgatgtgaa gacagcaagc ccatcaaaag
     9781 cgacagccta cattggctgg gcaccggacc cgtggagtct gcgcgtgcag agcaccacct
     9841 cctttgacgt gagcgacgcg cagggctaca aggtcgatgg ctataccacc gtggatctgc
     9901 tcggcagtta tcagcttccg gtgggtacac tcagcttcag cattgaaaac ctcttcgacc
     9961 gtgactacac cactgtctgg gggcagcgtg caccactgta ctacagcccg ggttacggcc
    10021 cagcgtcact gtacgactac aaaggcaggg gccgaacctt tggtctgaac tactctgtgc
    10081 tgttctgacc ggtattcctt tacaacaaag gtacgctgat atcaacatgg ccgctgacag
    10141 ccaagttgat atcatataat acacgacata atctgtagtc agggaggata gactctttac
    10201 tgactacaga ttatgtcgtg ttccgtgctc atttcctcaa aaaaatacaa gaaaagaatt
    10261 agtattctaa caaaaagtta gactggcccc ctgaatctcc agacaaccaa tatcacttaa
//
LOCUS       DAPGUL010000147        10240 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.150, whole genome shotgun sequence.
ACCESSION   DAPGUL010000147 DAPGUL010000000
VERSION     DAPGUL010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10240)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10240)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10240
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.150"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            36..5276
                     /locus_tag="RHX21_004084"
     CDS             36..5276
                     /locus_tag="RHX21_004084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001589595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inverse autotransporter beta-barrel
                     domain-containing protein"
                     /protein_id="HDV1989201.1"
                     /translation="MSSTNAHQIKNNIQNSLCGLGDKIRRLTAGVCLFTQIFSPVMAT
                     AQNVVHAKPQTTVSSAPPLIENNTVPYTLGALESAQSVADRFGISLEELRRLNQFRTF
                     ARGFDNVRQGEELDVPTTTSQKSHEQQNAVPPANGENTLENQIASTSQRVGTLLSQDM
                     NSEQASGMARGWASSEASGAMTDWLNNFGTAKISLGVDEDFSLKNSQFDFLHPWYDTP
                     DYLLFSQHTLHRTDDRTQINTGLGWRHFTPSWMSGINLFFDHDLSRYHSRAGLGAEYW
                     RDYLKLSSNAYIGLTGWRSAPELDNDYEARPANGWDLRAEGWLPAWPQLGGKLVYEQY
                     YGDEVALFDKNDRQSNPHAITAGLNYTPFPLLTLSAEQRQGKQGENDTRFAVDLTWQP
                     SSSMQKQLNPDEVAGRRSLAGSRYDLIDRNNNIVLEYRKKELIRLSLLDPVKGKSGEI
                     KPLVSSIQTKYALKGYNIEAAALEAAGGKVSTSGKDITVTLPGYRFTNTPETDNTWSI
                     DVTAEDVKGNLSRHEQSMVVIQAPTLSQKDSLLSVNPLTVAADKKSTTTLTVTAHDSD
                     GTPVPGLALQTRSEGVQDITLSDWTDNGDGSYTQMLTAGTTSGSVTLTPQINGESAVK
                     ESIVVNIVPVVSSRDHSSITIDNVSYYAGDDIKVRVELKDDSNQPVAYQKEELVKAVT
                     VENSKPGATIVWNEEQPGVYAANYPAHKQGTALRAQLSLHNWNAPLQSHIYNIEANQN
                     KARVATLSATNNDVYADKKTFNTLTINVTDESDNPLTNHQVTFKNEKGSAEFVEPPQQ
                     KTDAYGVATINMVSQVAEENTISATLPNGFSQRIIAKFVSDSSTPKFKQLVADPDTII
                     AGNSQGSTLTATVTDFHNNPLKDMKVNFVAPGGSQLDNTTATTDQSGIVRVHLTSSKA
                     GSYSVDASLEADKNIHQSVTITVVPNREQSVMTLNAGSGSAIANNTNTVILTASVKDV
                     YGHPLPDEDVKFTLPASMTGNFTLSSETARTDANGDAVVTLRGTEAGEFTVTATLTRN
                     NTVAHQQVTFIGDTNSAQLQPLIALLNTIVAGNNTGSTLTATILDAYQNPLKDQLVTF
                     QSNDVTLSGTEVTTNTLGQATVTMTSNIAGQHNVVVSRKTQPSDNKTFSLSVLPDESS
                     AKVISITGAEKTITVGENITLRILVQDAFNNVIAGQRVRLSAQPTAHITIGDTAYTDN
                     NGYAYVNLISTQSGVYQVTATLDNNSSSKVDVNVANGKLELTSSKPETTVHNSEGITL
                     TATARNARDELMPGQIITFSVTPEGATLSNTGEVLTDQYGQAKVTLTSDKVNVYTVTA
                     TMGKDVPVQRQVTVAVKADAKTAHVVSVVASPDTITADGVDNSTITSRVEDDYGFPVE
                     GVDVSYALDTKGSPVVNIPTTRTDQSGQVTATITSTLAETLTVNVQVPGTANQSATIT
                     LVAGTADESKSILKSDVDTLKADYQQSAKLTLTLQDKYGNPIVTSDHLEFVQSGPFVN
                     FLKLSDIDYSQRNYGEYTVTVTGGKEGTATLIPMLNGVHQAKLSVSLDLIHSIKEMSG
                     HVTANNHTFSTAKFPSEGFAGAYYTLNNDNFEAGKTVDDYMFSSSQSWVSVDASGKVS
                     FSNIGDQTSVTISAVPRQGGTTYQTLIKLKGWWVNNGNHTNIWLAANALCHAKNDGYT
                     LPGITHLTSGENKRTQGSLYGEWGNVGAFSSNSQFTQGAYWTSESDDYNRHYYVQMLT
                     GMTGSDADSSPQLTACRKSL"
     gene            complement(5397..5981)
                     /gene="kptA"
                     /locus_tag="RHX21_004085"
     CDS             complement(5397..5981)
                     /gene="kptA"
                     /locus_tag="RHX21_004085"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019842235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2'-phosphotransferase"
                     /protein_id="HDV1989202.1"
                     /translation="MAKYNEKELADTSKFLSYVLRHKPEAIGIVLDREGWADIDKLIL
                     CAQKAGKRLTRALLDTVVATSDKKRFSYSSDGRCIRAVQGHSTSQVAISFAEKTPPQF
                     LYHGTASRFLDEIKKQGLIAGERHYVHLSADEATARKVGARHGSPVILTVKAQEMAKR
                     GIPFWQAENGVWLTTTVAVEFLEWPFMPAGKQKQ"
     gene            6231..6914
                     /locus_tag="RHX21_004086"
     CDS             6231..6914
                     /locus_tag="RHX21_004086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418750.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989203.1"
                     /translation="MTQQGDAVAGELATEKVGIKGYLAFFLTIIFFSGVFSGTDSWWR
                     VFDFSVLNGSFGQLPGANGATTSFRGAGGAGAKDGFLFALELAPSVILSLGIISITDG
                     LGGLRAAQQLMTPVLKPLLGIPGICSLALIANLQNTDAAAGMTKELAQEGEITERDKV
                     IFAAYQTSGSAIITNYFSSGVAVFAFLGTSVIVPLAVILVFKFVGANILRVWLNFEER
                     RNPTQGAQA"
     gene            6911..7372
                     /locus_tag="RHX21_004087"
     CDS             6911..7372
                     /locus_tag="RHX21_004087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HDV1989204.1"
                     /translation="MTTQVRKNVMDMFIDDARRGFTIATTNLLPNVVMAFVIIQALKI
                     TGLLDWVGHICEPVMALWGLPGEAATVLLAALMSMGGAVGVAASLATAGALTGHDVTV
                     LLPAMYLMGNPVQNVGRCLGTAEVNAKYYPHIITVCVINALLSIWVMQLIV"
     gene            7385..8557
                     /gene="iadA"
                     /locus_tag="RHX21_004088"
     CDS             7385..8557
                     /gene="iadA"
                     /locus_tag="RHX21_004088"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HDV1989205.1"
                     /translation="MIDYTAAGFTLLQGAHLYAPEDRGVCDVLVANGKIIAVASNIPS
                     DIVPDCTVVDLSGQILCPGFIDQHVHLIGGGGEAGPTTRTPEVALSRLTEAGVTSVVG
                     LLGTDSISRHPESLLAKTRALNEEGISAWMLTGAYHVPSRTITGSVEKDVAIIDRVIG
                     VKCAISDHRSAAPDVYHLANMAAESRVGGLLGGKPGVTVFHMGDSKKALQPVYDLLEN
                     CDVPISKLLPTHVNRNVPLFEQALEFAHKGGTIDITSSIDEPVAPAEGIARAVQAGIP
                     LARVTLSSDGNGSQPFFDDEGNLTHIGVAGFETLLETVQVLVKDYDFSISDALRPLTS
                     SVAGFLNLSGKGEILPGNDADLLVMTPELRIEQVYARGKLMVKDGKACVKGTFETA"
     gene            8622..9533
                     /gene="hypT"
                     /locus_tag="RHX21_004089"
                     /gene_synonym="qseD"
     CDS             8622..9533
                     /gene="hypT"
                     /locus_tag="RHX21_004089"
                     /gene_synonym="qseD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypochlorite stress DNA-binding transcriptional
                     regulator HypT"
                     /protein_id="HDV1989206.1"
                     /translation="MDDCGAVLHNIETKWLYDFLTLEKCRNFSQAAVSRNVSQPAFSR
                     RIRALEQAIGVELFNRQVTPLQLSEQGKIFHSQIRHLLQQLESNLAELRGGSDYAQRK
                     IKIAAAHSLSLGLLPSIISQMPPLFTWAIEAIDVDEAVDKLREGQSDCIFSFHDEDLL
                     EAPFDHIRLFESQLFPVCASDEHGEALFTLAQPHFPLLNYSRNSYMGRLINRTLTRHS
                     ELSFSTFFVSSMSELLKQVALDGCGIAWLPEYAIQQEIRSGQLVVLNREELVIPIQAY
                     AYRMNTRMNPVAERFWRELRELEIVLS"
     gene            complement(9526..9918)
                     /gene="iraD"
                     /locus_tag="RHX21_004090"
     CDS             complement(9526..9918)
                     /gene="iraD"
                     /locus_tag="RHX21_004090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418746.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraD"
                     /protein_id="HDV1989207.1"
                     /translation="MMRQSLQAVLPEISGNKTSSLRKSVCSDLLTLFNSPHSALPSLL
                     VSGMPEWQVHNQSDKHLQSWYCRQLRSALLFHEPRIAALQVNLKEAYSHTLAISLEIM
                     LYHDDEPLTFDLVWDNGGWRSATLENVS"
     gene            complement(9915..9998)
                     /gene="idlP"
                     /locus_tag="RHX21_004091"
     CDS             complement(9915..9998)
                     /gene="idlP"
                     /locus_tag="RHX21_004091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iraD leader peptide IdlP"
                     /protein_id="HDV1989208.1"
                     /translation="MENEHQYSGARCSGQAAYVAKRQECAK"
BASE COUNT         2686 a         2601 c         2517 g         2436 t
ORIGIN      
        1 acaagtttaa ttctgttttt tcacggaagg tcactatgtc ttcaacaaat gcgcatcaaa
       61 taaaaaataa tattcaaaat tctttatgtg gtctgggtga caaaatacgc cgcctgaccg
      121 ccggagtttg tttatttaca caaatttttt cccccgtcat ggcgacggca caaaatgtgg
      181 tacacgctaa acctcagacg acagtttcat ctgccccccc tctaatagaa aataatactg
      241 tgccttacac gcttggagcg ctggaatcag cgcaaagcgt tgctgatcga ttcggtattt
      301 cactggagga gcttcgtcgt cttaatcagt tccgtacttt tgctcgcggc tttgataacg
      361 tgcgccaggg tgaggaactg gatgttccga caacaacctc gcagaaaagt catgagcaac
      421 aaaatgccgt accgcctgcg aatggcgaaa acacgctgga gaatcaaata gccagcactt
      481 cgcagcgagt tggcactctg ctttcacaag atatgaatag tgagcaggcc agcggcatgg
      541 cgcgtggttg ggcgtcttca gaagcctcag gcgcgatgac tgattggtta aataactttg
      601 gcactgcgaa aatctctctg ggtgtggatg aagatttcag cctgaaaaat tcgcaattcg
      661 acttcctgca tccgtggtat gacacacccg attatctgct cttcagccag catacccttc
      721 accgaacaga cgaccgtacc cagatcaaca ccggtttggg ctggcgtcat ttcaccccca
      781 gctggatgtc aggcatcaac ctgttttttg accacgacct gagccgctat cactcccgcg
      841 cggggcttgg cgcagaatac tggcgtgatt atctgaagtt gagcagcaac gcttatatcg
      901 gcctgaccgg ctggcgtagc gcaccggaat tggataatga ctacgaagcc cgcccggcca
      961 acggctggga tttacgcgcg gaaggctggt taccagcctg gccacaactg ggtggaaaac
     1021 tggtctatga acaatactat ggtgatgaag tggcgctgtt tgacaagaat gatcgccaaa
     1081 gtaatcccca tgctattacc gcgggcctca actatacccc cttcccgctt ctgactctca
     1141 gtgcagaaca gcgtcagggg aagcaaggtg aaaatgacac acgttttgcc gttgatctga
     1201 cctggcaacc cagcagctca atgcagaaac agcttaaccc ggacgaagtg gccggacggc
     1261 gcagtctggc cggtagtcgt tatgacctga ttgatcgcaa caacaatatc gttctggaat
     1321 atcgcaagaa agagctgatt cgcctgagtc tgctggatcc ggtgaaagga aagtctggag
     1381 aaataaaacc gctggtttcc tcgatacaga ccaaatatgc cctgaaaggc tataacatcg
     1441 aagccgctgc gctggaagct gccggaggta aagtcagcac gtctggaaaa gatatcacgg
     1501 tcacgctgcc aggttaccgc ttcactaaca ctccagaaac cgataataca tggtcgatag
     1561 acgttaccgc cgaggatgta aaaggtaacc tgtcacgtca tgaacaaagc atggtcgtca
     1621 ttcaggctcc gacattaagc cagaaagatt ctctgttatc cgttaatccg ctaaccgtag
     1681 ctgcagataa aaaatcgacg accacattga ccgttactgc gcacgattcc gacggaactc
     1741 cggtgccggg gctggcgctg caaactcgca gtgaaggcgt tcaggatatc accctgtctg
     1801 actggacaga taacggtgat ggtagttaca cacagatgct gaccgccgga acgacatcag
     1861 gttcagtaac actgacgccg caaattaacg gtgagagtgc ggtaaaagaa tccatcgtcg
     1921 ttaatatcgt ccctgttgtc tcatcccgcg accattcttc aataacaata gataacgtat
     1981 cgtattatgc cggagacgac atcaaggtta gggtggaact gaaagacgac agcaatcaac
     2041 cggttgctta tcaaaaagaa gaattggtaa aagccgttac tgtcgaaaac agcaaacctg
     2101 gagccacgat tgtctggaac gaagagcagc cgggcgttta tgccgcgaat tatccggccc
     2161 ataagcaagg aacagcacta agggcacaac ttagccttca caactggaat gctccactgc
     2221 aatcgcatat ttataacatt gaggctaacc agaataaggc tcgcgtcgcc acattatcag
     2281 cgacgaataa tgacgtttac gccgataaaa agacatttaa taccctcact atcaacgtca
     2341 ctgatgagag tgataatccc ctgacaaatc atcaggtcac ctttaagaat gaaaaaggaa
     2401 gcgcggaatt tgtcgaaccg ccgcagcaaa aaacggatgc atacggtgtt gccacaatca
     2461 acatggtaag tcaggttgct gaagaaaata cgattagtgc cacgctgcca aatggtttct
     2521 cacaacggat aattgcgaaa ttcgttagcg attcgagtac gccaaaattc aaacaactgg
     2581 ttgccgatcc agataccatt attgctggca acagccaggg cagtactctg accgccaccg
     2641 tcacagactt tcataacaat ccattaaaag atatgaaagt gaattttgtg gcaccaggtg
     2701 gctcgcaact ggacaacacg accgccacca cagaccagtc cggtattgtg cgagtgcacc
     2761 tgaccagttc aaaagctggt agctattccg tcgatgcctc gcttgaggcg gataaaaata
     2821 ttcaccagtc ggtcacgatc accgtggtcc caaacaggga acaatcggta atgaccttaa
     2881 atgccgggtc aggcagtgcg atcgctaaca atacaaatac cgttatcctg acagccagtg
     2941 tgaaagatgt gtatggacac ccgttgccgg atgaggatgt gaaatttacc ttgccagcct
     3001 ccatgaccgg aaacttcacg ctaagtagtg aaaccgcccg caccgatgca aacggcgatg
     3061 ccgtggtcac attgcgaggc acagaagcgg gtgagtttac agttacggcg acgctgacca
     3121 gaaataatac cgttgctcat cagcaagtca cttttattgg ggatacaaac agcgcgcagc
     3181 tccagccgct gattgcctta ttaaatacca ttgttgcggg taacaatacg gggagtaccc
     3241 tgacggcaac gatcctggac gcttaccaaa atccgcttaa agaccagctg gtcactttcc
     3301 agagtaacga tgtcactcta agcggaacag aagtcaccac caatacgctg ggtcaggcga
     3361 cggtaacaat gaccagcaat attgccggac aacataacgt cgtggtgagc cggaaaacgc
     3421 aaccctccga taataaaacg tttagtttat cagtgctccc ggatgaaagt tcggcgaagg
     3481 ttataagtat aaccggagcc gaaaaaacga taacggttgg tgaaaacatc acgctacgga
     3541 tactcgtcca ggacgcgttt aacaatgtaa tagcgggtca acgcgtcaga ttaagtgcgc
     3601 agccaacagc tcacattacg ataggcgata cggcttacac cgataataac ggttatgcgt
     3661 acgttaacct tattagcacc cagtctgggg tttatcaggt gacggcaacg ctggacaata
     3721 acagtagtag taaggttgac gtgaatgtgg caaatggcaa gctcgagtta acatcatcga
     3781 agccagaaac cacggtccat aacagtgaag gtattacgct taccgcaacg gcgagaaatg
     3841 ctcgggatga attaatgcct gggcaaatta tcacctttag cgtaacgcct gaaggtgcaa
     3901 cgctaagcaa tacaggggaa gtccttactg accagtatgg tcaggccaaa gtgacgctga
     3961 ccagtgacaa agtgaatgtc tataccgtta cggccacaat gggcaaagat gttcccgttc
     4021 agagacaggt aacggttgcg gttaaggcag atgctaaaac ggcacatgtt gtgagcgtcg
     4081 tggcctctcc tgacaccata accgccgacg gcgttgataa cagcaccatc acttcacgag
     4141 tagaagatga ttacggattc ccggttgaag gtgtcgatgt tagttatgcc ttagacacca
     4201 aaggcagccc ggtagttaat attccaacta cgcgtaccga tcagtccggg caagtcacgg
     4261 cgacaataac cagtacattg gcagaaactt taacagtcaa tgtgcaagtt cctggtacag
     4321 ccaaccaatc cgcaaccatt acattggttg ccggcacggc cgatgaaagt aagtcaattt
     4381 tgaaatccga cgttgacact ttgaaggctg actaccagca gagcgcaaaa cttacgctaa
     4441 cattgcaaga caagtacggt aacccgatag tgacgtctga tcatctggaa tttgtccagt
     4501 caggcccctt cgtgaacttt ctcaagttga gcgatattga ttacagccaa agaaattatg
     4561 gcgagtacac tgtgactgtc actggcggaa aagagggaac agcgaccctc attcccatgc
     4621 tgaacggggt tcatcaggca aaattaagcg tatcgctgga tctcatccac tcgataaaag
     4681 aaatgtccgg tcatgtcact gcaaacaacc ataccttctc cacggctaaa ttcccgagcg
     4741 aaggttttgc aggagcgtat tacacactca acaatgataa ctttgaagcg ggtaaaaccg
     4801 ttgatgatta tatgttttca agttcacaga gttgggtgtc tgtcgatgcg tcaggtaaag
     4861 tttctttctc aaatatcggc gatcaaacgt cagtcacaat aagtgctgtt ccccgacaag
     4921 gaggtacaac ctaccagacc ttaattaagc tgaaaggctg gtgggtgaat aatggaaatc
     4981 ataccaatat ctggctagct gccaatgcgc tctgtcatgc gaaaaatgat ggatatactc
     5041 ttcctggcat cacacatttg acgtctggcg aaaacaaacg cacgcaggga tcactgtatg
     5101 gtgaatgggg gaacgttgga gcgttttcca gtaattcgca atttacacaa ggagcttact
     5161 ggacaagtga atctgatgat tacaatcggc actactatgt gcagatgcta acgggtatga
     5221 ccggaagcga cgctgattcc agcccccaac tgaccgcctg ccgcaaatca ctttaatttc
     5281 agcaggttat taaggatacc cttgtgcgag ggtatccttt ccgactgata acaaacgcta
     5341 cattgcctga tccgctgcgc ttatcaggcc tatataaccc ctgcaatatc ttgaatttat
     5401 tgtttttgtt tccctgccgg catgaacggc cactcaagaa actcaacagc aaccgttgtt
     5461 gtcagccaga ccccgttttc cgcttgccag aaagggatgc ctcgtttcgc catttcctgt
     5521 gctttgacgg ttaagataac cggcgatccg tgtcttgctc ccactttgcg tgccgttgct
     5581 tcatcagcag agagatgcac gtaatgacgc tcccctgcaa tcagcccctg tttttttatc
     5641 tcgtcaagga aacggcttgc cgtaccgtgg taaagaaact gtggcggtgt tttttcggca
     5701 aaggaaatgg cgacctgcga agtcgaatgc ccctgaaccg cgcgaatgca cctaccatca
     5761 ctggagtaac taaaacgctt tttatcgctg gtggcgacaa cggtatccag caatgcacgg
     5821 gttaaccgct tgcccgcttt ttgggcacaa agtatgagct tatcgatatc cgcccatcct
     5881 tcacggtcca gtacgatacc aatcgcctcc ggtttgtgtc ggaggacata acttaaaaac
     5941 ttgctcgtat ccgccagctc tttttcgttg tactttgcca tctcattttc gtccctggat
     6001 tttctgtttt aatttactga tgtcattgtc actgggttta tgaatttact gcaactccat
     6061 cctgcgcaga accttttcca cacagcgtaa tttttccgct atgcaaaaaa cgcatagcca
     6121 gaaacatact tgcattttcc ccatacccac atggctgata aggtttttcg gctccaggaa
     6181 ttttcctggc tcaagcaaca cacaaacaca aaaaaacaat ggggattgtt atgacacaac
     6241 aaggggatgc tgtagccggg gagctggcga cagaaaaagt gggcattaaa gggtatcttg
     6301 ctttttttct caccataatc tttttttccg gtgttttttc cgggacagac agttggtggc
     6361 gcgtttttga tttttccgtg ctgaacgggt cgtttgggca actgcctggt gcgaacggag
     6421 ccaccacctc gtttcgcggc gcgggtggcg cgggggctaa agatggcttt ctctttgcgc
     6481 tggagctggc accgtcagtc attctctctc tggggattat ttcaattact gatggtcttg
     6541 gcggattacg cgccgcgcag cagttaatga cgccagtgct aaaaccgttg ttgggcattc
     6601 cagggatctg ctcgctggcg ctgatcgcta acctgcaaaa caccgatgcc gccgccggta
     6661 tgaccaaaga gctggcgcag gaaggtgaaa ttaccgaacg cgataaagtg attttcgccg
     6721 catatcaaac cagcggtagc gccattatca ccaactactt ctcttccggc gtcgcggtgt
     6781 ttgcctttct gggcacatcc gtaatcgtac ctttagccgt catcctggtg tttaaatttg
     6841 tcggagccaa cattttgcgc gtctggctta acttcgaaga acgtcgcaac ccaacgcaag
     6901 gagcgcaagc atgacaactc aggtccgcaa aaacgtcatg gatatgttta tcgatgacgc
     6961 gcgccgtggc tttactatcg ccaccaccaa cctgctgcca aacgtggtga tggcgtttgt
     7021 catcattcag gcgctgaaaa ttaccggcct gctcgactgg gtggggcata tctgtgaacc
     7081 ggtaatggcg ctgtggggat tgccaggtga agcggcaacc gtccttttag ccgcattaat
     7141 gagtatgggc ggcgcagtcg gtgttgccgc cagtctggca accgctggcg cattaaccgg
     7201 tcacgatgtc accgttttac tgcccgcgat gtatttaatg ggcaacccgg tgcaaaatgt
     7261 cggtcgctgc ctggggacag ccgaagtgaa tgccaaatat tacccgcata tcattacggt
     7321 ctgcgtgatt aacgcattgc tgtcgatctg ggttatgcag cttattgttt aacaaggagt
     7381 taccatgatt gattataccg cagccggttt taccctgctg cagggagcgc atttgtatgc
     7441 gccggaagat cggggagttt gcgatgtcct cgtcgctaac ggcaaaatta tcgccgttgc
     7501 cagtaatatc ccttctgaca ttgtaccgga ctgcacggtt gtcgatctca gcgggcagat
     7561 cctctgccca ggttttattg atcaacacgt tcatttgatt ggcggtggcg gtgaagcagg
     7621 tcccacgacg cgcacaccgg aagtggcgtt aagtcgtctg acggaagcgg gcgtcacgtc
     7681 agtggttggt ctgctcggca ctgactctat ctctcgtcac ccggaatccc tgctcgccaa
     7741 gacccgtgcg ctcaatgaag aaggcatcag cgcctggatg ctgaccggcg cttatcatgt
     7801 cccttcccgc accattacag gttccgtgga aaaagacgtg gcgattatcg atcgcgtgat
     7861 tggtgtgaaa tgcgccatct ctgatcaccg ttctgccgca cctgacgttt atcacctggc
     7921 taatatggcg gcggaatccc gcgttggcgg tttgctcggc ggcaaacctg gcgtcactgt
     7981 gttccacatg ggcgacagca aaaaggcgtt acagcctgtc tatgacctgc tggaaaactg
     8041 cgatgtgccg atcagcaagc tgctgccgac ccacgttaac cgcaacgttc cgttgtttga
     8101 gcaggcgctg gagtttgcgc acaaaggcgg cactatcgac atcaccagca gcattgacga
     8161 accggtcgcc cctgccgaag gtattgcccg tgccgttcag gccggtattc cgctggcacg
     8221 cgtcaccctc agctccgacg gcaacggtag ccagccgttc ttcgatgacg aagggaattt
     8281 aacccatatc ggtgttgcag gttttgaaac gttgctggaa accgtgcagg tgctggtcaa
     8341 agactatgat ttcagtatca gcgatgccct gcgcccgctc accagtagcg tagccggttt
     8401 ccttaacctg agcgggaaag gcgaaattct gccaggcaat gacgcagact tactggtcat
     8461 gacgccagaa ttgcgcattg agcaggtata cgctcgcggc aaactgatgg tcaaagacgg
     8521 caaagcctgc gtgaaaggaa cgtttgaaac ggcttaaacg gttgtcagcc gcccgaatgg
     8581 acgtagaatg cccgcaaggg cggctgacag agtaaaacgt aatggatgac tgtggtgcgg
     8641 ttttgcataa tattgaaaca aaatggcttt atgattttct gaccctggaa aaatgccgca
     8701 acttttccca ggcggcagtc agtcgcaacg tctcgcaacc ggcattcagc cgccgcatcc
     8761 gtgcactgga acaggcgatt ggcgttgaat tgtttaaccg ccaggtgacg ccgctgcaac
     8821 tctcggaaca agggaaaatc ttccattcgc agatccgcca tctgttgcaa cagttagaaa
     8881 gcaacctggc agagctgcgt ggcggcagcg attatgcgca acgtaaaatc aagatagccg
     8941 ctgcacactc tctttccctc ggtctgttac cgtccattat cagccagatg ccgccgctct
     9001 ttacctgggc gattgaagcc attgatgtcg atgaagcggt cgataaactg cgtgaagggc
     9061 aaagtgactg tattttttcc tttcacgacg aagatttgct ggaagcgccg tttgaccaca
     9121 ttcgcttatt tgaatctcaa ttgttccccg tctgcgccag tgacgaacac ggagaagcac
     9181 tgtttaccct cgcgcagcca cactttccgt tactgaatta cagccgcaac tcctacatgg
     9241 ggcgattgat taatcgcacc ctgacgcgcc acagcgagtt aagtttcagc accttttttg
     9301 tctcttcgat gagcgagcta ttaaagcagg ttgccctcga cggctgtggg attgcctggc
     9361 tgccggaata cgccatccaa caagaaattc gcagcgggca gctcgttgta ctgaatcggg
     9421 aagaactggt gatcccgatt caggcctacg catacaggat gaacacccgt atgaatcccg
     9481 ttgccgaacg cttctggcgt gaactgcgcg aactggagat tgtgcttagc tgacattctc
     9541 cagcgtcgca ctacgccaac cgccattatc ccagaccaga tcaaacgtta gcggttcatc
     9601 gtcgtggtac agcattatct caaggctgat cgccagcgtg tggctgtacg cttctttcaa
     9661 attgacctgc aacgccgcaa tccgtggctc atgaaataac agtgcagaac gcagctgacg
     9721 gcaataccag ctctgaagat gtttgtcgct ctggttatgc acttgccact cgggcatgcc
     9781 tgaaacaagt aatgacggta atgccgaatg aggagaatta aaaagagtga ggagatcgct
     9841 gcataccgat ttacgcagcg atgacgtttt attgcctgaa atttcaggta aaacagcctg
     9901 aagtgattgg cgcatcattt tgcgcactcc tgacgtttag caacatatgc ggcttgccct
     9961 gaacaccggg caccactgta ttgatgctca ttttccatag ccattccctt ttgttcatta
    10021 catccatgtc agtctgagac aggcctgaat cctgtcagca aagtataaaa ccttacttgc
    10081 ctatgaatat ctactgactt ttcaggaaaa aagtcatgat ttgataaaaa tcatcaaact
    10141 caaaaaaaaa ccgctactat attctgaata ttccgaatag ttacgcagat gaaaatactt
    10201 gtcaccgtcg ctacataatc ccggaaagca attatttatc
//
LOCUS       DAPGUL010000148        10124 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.151, whole genome shotgun sequence.
ACCESSION   DAPGUL010000148 DAPGUL010000000
VERSION     DAPGUL010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10124
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.151"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(80..856)
                     /gene="yaaA"
                     /locus_tag="RHX21_004092"
     CDS             complement(80..856)
                     /gene="yaaA"
                     /locus_tag="RHX21_004092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HDV1989209.1"
                     /translation="MLILISPAKTLDYQSPLTTMRYTLPELLDNSQQLIHEARKLTPP
                     QISTLMRISDKLAGINAARFHDWQPDFTPENARQAILAFKGDVYTGLQAETFSEDDFD
                     FAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENARGKDLYQFWGDIITNKLNEALA
                     AQGDNVVINLASDEYFKSVKPKKLNAEIIKPVFLDEKNGKFKIISFYAKKARGLMSRF
                     IIENRLTKPEQLTGFNSEGYFFDEASSSNGELVFKRYEQR"
     gene            complement(926..2356)
                     /locus_tag="RHX21_004093"
     CDS             complement(926..2356)
                     /locus_tag="RHX21_004093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HDV1989210.1"
                     /translation="MPDFFSFINSVLWGSVMIYLLFGAGCWFTFRTGFVQFRYIRQFG
                     KSLKNSIHPQPGGLTSFQSLCTSLAARVGSGNLAGVALAITAGGPGAVFWMWVAAFIG
                     MATSFAECSLAQLYKERDVNGQFRGGPAWYMARGLGMRWMGVLFAVFLLIAYGIIFSG
                     VQANAVARALSFSFDFPPLVTGIILAVFTLLAITRGLHGVARLMQGFVPLMAIIWVLT
                     SLVICVMNIGQLPHVIWSIFESAFGWQEAAGGAAGYTLSQAITNGFQRSMFSNEAGMG
                     STPNAAAAAASWPPHPAAQGIVQMIGIFIDTLVICTASAMLILLAGNGTTYMPLEGIQ
                     LIQKAMRVLMGSWGAEFVTLVVILFAFSSIVANYIYAENNLFFLRLNNPKAIWCLRIC
                     TFATVIGGTLLSLPLMWQLADIIMACMAITNLTAILLLSPVVHTIASDYLRQRKLGVR
                     PVFDPLRYPDIGRQLSPDAWDDVSQE"
     gene            2635..3588
                     /gene="tal"
                     /locus_tag="RHX21_004094"
     CDS             2635..3588
                     /gene="tal"
                     /locus_tag="RHX21_004094"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HDV1989211.1"
                     /translation="MTDKLTSLRQYTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQ
                     IPEYRKLIDDAVAWAKQQSNDRAQQIVDATDKLAVNIGLEILKLVPGRISTEVDARLS
                     YDTEASIAKAKRLIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFS
                     FAQARACAEAGVFLISPFVGRILDWYKANSDKKEYAPAEDPGVVSVSEIYQYYKEHGY
                     ETVVMGASFRNIGEILELAGCDRLTIAPALLKELAESEGAIERKLSYTGEVKARPARI
                     TESEFLWQHNQDPMAVDKLAEGIRKFAIDQEKLEKMIGDLL"
     gene            3703..4290
                     /gene="mog"
                     /locus_tag="RHX21_004095"
     CDS             3703..4290
                     /gene="mog"
                     /locus_tag="RHX21_004095"
                     /EC_number="2.7.7.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin adenylyltransferase"
                     /protein_id="HDV1989212.1"
                     /translation="MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELET
                     RLIPDEQAIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQ
                     MRQISLHFVPTAILSRQVGVIRKQALILNLPGQPKSIKETLEGVKDAAGNVVVHGIFA
                     SVPYCIQLLEGPYVETAPEVVAAFRPKSARRDVSE"
     gene            complement(4325..4891)
                     /gene="satP"
                     /locus_tag="RHX21_004096"
     CDS             complement(4325..4891)
                     /gene="satP"
                     /locus_tag="RHX21_004096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate uptake transporter"
                     /protein_id="HDV1989213.1"
                     /translation="MGNTKLANPAPLGLMGFGMTTILLNLHNVGYFALDGIILAMGIF
                     YGGIAQIFAGLLEYKKGNTFGLTAFTSYGSFWLTLVAILLMPKLGLTDAPNAQFLGVY
                     LGLWGVFTLFMFFGTLKGARVLQFVFFSLTVLFALLAIGNIAGNAAIIHFAGWIGLIC
                     GASAIYLAMGEVLNEQFGRTVLPIGESH"
     gene            complement(5040..5753)
                     /gene="msyB"
                     /locus_tag="RHX21_004097"
     CDS             complement(5040..5753)
                     /gene="msyB"
                     /locus_tag="RHX21_004097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acidic protein MsyB"
                     /protein_id="HDV1989214.1"
                     /translation="MNVNYLNDSDLDFLQHCSEEQLANFARLLTHNEKGKTRLSSVLM
                     RNELFKSMEGHPEQHRRNWQLIAGELQHFGGDSIANKLRGHGKLYRAILLDVSKRLKL
                     KADKEMSTFEIEQQLLEQFLRNTWKNMDEEHKQEFLHAIDARVNELEELLPLLMKDKL
                     LAKGVSHLLSSQLTRILRTHAAMSVLGHGLLRGAGLGGPVGAALNGVKAVSGSAYRVT
                     IPAVLQIACLRRMVSATQV"
     gene            complement(5779..6183)
                     /locus_tag="RHX21_004098"
     CDS             complement(5779..6183)
                     /locus_tag="RHX21_004098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2541 family protein"
                     /protein_id="HDV1989215.1"
                     /translation="MKSVFTISASLAISLMLCCTAQANDHKLLGVIAMPRNETNDLAL
                     KLPVCRIVKRIQLSADHGDLQLSGASVYFKAARSASQSLNIPSEIKEGQTTDWININS
                     DNDNKRCVSKITFSGHTVNSSDMATLKIIGDD"
     gene            6560..8476
                     /gene="dnaK"
                     /locus_tag="RHX21_004099"
     CDS             6560..8476
                     /gene="dnaK"
                     /locus_tag="RHX21_004099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001737966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HDV1989216.1"
                     /translation="MGKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQ
                     DGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAW
                     VEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRI
                     AGLEVKRIINEPTAAALAYGLDKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEV
                     LATNGDTHLGGEDFDSRLINYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSA
                     QQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDI
                     DDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLL
                     DVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAAD
                     NKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLN
                     EDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIE
                     SALTALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQTAGADASANNAKDD
                     DVVDAEFEEVKDKK"
     gene            8565..9695
                     /gene="dnaJ"
                     /locus_tag="RHX21_004100"
     CDS             8565..9695
                     /gene="dnaJ"
                     /locus_tag="RHX21_004100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HDV1989217.1"
                     /translation="MAKQDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAE
                     AKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGGMGGGGFGGGADFSDIFGDVFGDIF
                     GGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKPGTQPQT
                     CPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERSKTLSVKIPA
                     GVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAAL
                     GGEIEVPTLDGRVKLKVPGETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLN
                     EKQKQLLQELQESFGGPTGEHNSPRSKSFFDGVKKFFDDLTR"
     gene            complement(9799..9951)
                     /gene="mokC"
                     /locus_tag="RHX21_004101"
     CDS             complement(9799..9951)
                     /gene="mokC"
                     /locus_tag="RHX21_004101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin MokC"
                     /protein_id="HDV1989218.1"
                     /translation="MKQHKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVF
                     TAYESE"
BASE COUNT         2658 a         2539 c         2630 g         2297 t
ORIGIN      
        1 aattctgcaa tatattgaat ctgcatgctt ttgtaggccg gataaggcgt tcacgccgca
       61 tccggcattg gctacaaact taacgctgct cgtagcgttt aaacaccagt tcaccattgc
      121 tggaggaagc ttcatcaaag aagtaacctt cgctattaaa accagtcagt tgctctggtt
      181 tggtcagccg attttcaata atgaaacgac tcatcagacc gcgtgctttc ttagcgtaga
      241 agctgatgat cttaaatttg ccgttcttct catcgaggaa caccggcttg ataatctcgg
      301 cattcaattt cttcggcttc accgatttaa aatactcatc tgacgccaga ttaatcacca
      361 cattatcgcc ttgtgctgcg agcgcctcgt tcagcttgtt ggtgatgata tctccccaga
      421 attgatacag atctttccct cgggcattct caagacggat ccccatttcc agacgataag
      481 gctgcattaa atcgagcggg cgcagtacgc catacaagcc ggaaagcatt cgcaaatgct
      541 gttgggcaaa atcgaaatcg tcttcgctga aggtttcggc ctgcaagccg gtgtagacat
      601 cacctttaaa cgccagaatc gcctggcggg cattctccgg cgtgaaatct ggctgccagt
      661 catgaaagcg agcggcgttg atacccgcca gtttgtcgct gatgcgcatc agcgtgctaa
      721 tctgcggagg cgtcagtttc cgcgcttcat ggatcaactg ctgggaattg tctaacagct
      781 ccggcagcgt atagcgcatg gtggtcaacg ggctttggta atcaagcgtt ttcgcaggtg
      841 aaataagaat cagcatatcc agtccttgca ggaaatttat gccgacttta gcaaaaaaag
      901 agaatgagtt gatcgatagt tgtgattact cctgcgaaac atcatcccac gcgtccggag
      961 aaagctggcg accgatatcc ggataacgca acggatcaaa caccgggcgc acgccgagtt
     1021 tacgctggcg tagataatca ctggcaatgg tatgaaccac aggcgagagc agtaaaatgg
     1081 cggtcaaatt ggtaatagcc atgcaggcca ttatgatatc tgccagttgc cacatcagcg
     1141 gaagacttag caaggtgccg ccgatgaccg ttgcgaaggt gcagatccgc aaacaccaga
     1201 tcgctttagg gttgttcagg cgtaaaaaga agagattgtt ttcggcataa atgtagttgg
     1261 caacgatgga gctgaaggca aacagaataa ccacgagggt aacaaactca gcaccccagg
     1321 aacccattag cacccgcatc gccttctgga taagctgaat accttccagc ggcatgtagg
     1381 ttgtgccgtt acccgccagt aatatcagca tggcgcttgc cgtacagatg accagggtgt
     1441 cgataaaaat gccaatcatc tggacaatcc cttgagctgc cggatgcgga ggccaggacg
     1501 cagctgccgc tgctgcgttt ggtgtagaac ccattcccgc ctcattggaa aacatactgc
     1561 gctgaaaacc gttagtaatc gcctggctta aggtatatcc cgccgcgccg cctgccgctt
     1621 cctgccagcc aaaagcactc tcaaaaatag accaaatgac gtggggaagt tgcccgatat
     1681 tcattacgca aatcaccagg ctggtcagta cccagattat cgccatcaac gggacaaaac
     1741 cctgcatgag ccgggcgacg ccatgaagac cgcgagtgat tgccagcaga gtaaagacag
     1801 cgagaataat gcctgtcacc agcgggggaa aatcaaaaga aaaactcagg gctcgggcaa
     1861 cggcgttcgc ctgaactccg ctgaaaatta tgccataggc gatgagcaaa aagacggcga
     1921 acagaacgcc catccaacgc atccccagcc cgcgcgccat ataccatgcc ggtccgccac
     1981 gaaactgtcc attgacgtca cgttctttat aaagttgtgc cagagaacat tcggcaaacg
     2041 aggtcgccat gccgataaac gcggcaaccc acatccaaaa gacggctcca ggtccaccgg
     2101 cggtaattgc cagcgcaacg ccggccaggt tgccgctacc cacgcgcgcc gcaagactgg
     2161 tacacaatga ctgaaatgag gttaaaccgc ctggctgtgg atgaatgcta tttttaagac
     2221 ttttgccaaa ctggcggatg tagcgaaact gcacaaatcc ggtgcgaaaa gtgaaccaac
     2281 aacctgcgcc gaagagcagg taaatcatta ccgatcccca aaggacgctg ttaataaagg
     2341 agaaaaaatc tggcatgcat atccctctta ttgccggtcg cgatgacttt cctgtgtaaa
     2401 cgttaccaat tgtttaagaa gtatatacgc tacgaggtac ttgataactt ctgcgtagca
     2461 tacatgaggt tttgtataaa aatggcgggc gatatcaacg cagtgtcaga aatccgaaac
     2521 agtctcgcct ggcgataacc gtcttgtcgg cggttgcgct gacgttgcgt cgtgatatca
     2581 tcagggcaga ccggttacat ccccctaaca agctgtttaa agagaaatac tatcatgacg
     2641 gacaaattga cctcccttcg tcagtacacc accgtagtgg ccgacactgg ggacatcgcg
     2701 gcaatgaagc tgtatcaacc gcaggatgcc acaaccaacc cttctctcat tcttaacgca
     2761 gcgcagattc cggaataccg taagttgatt gatgatgctg tcgcttgggc gaaacagcag
     2821 agcaacgatc gcgcgcagca gatcgtggac gcgaccgaca aactggcagt aaatattggt
     2881 ctggaaatcc tgaaactggt tccgggccgt atctcaactg aagttgatgc gcgtctttcc
     2941 tatgacaccg aagcgtcaat tgcgaaagca aaacgcctga tcaaactcta caacgatgct
     3001 ggtattagca acgatcgtat tctgatcaaa ctggcttcta cctggcaggg tatccgtgct
     3061 gcagaacagc tggaaaaaga aggcatcaac tgtaacctga ccctgctgtt ctccttcgct
     3121 caggctcgtg cttgtgcgga agcaggcgtg ttcctgatct cgccatttgt tggccgtatt
     3181 cttgactggt acaaagcgaa tagtgataag aaagagtacg ctccggcaga agatccgggc
     3241 gtggtttctg tatctgaaat ctaccagtac tacaaagagc acggttatga aacagtggtt
     3301 atgggcgcaa gcttccgtaa catcggcgaa attctggaac tggcaggctg cgaccgtctg
     3361 accatcgcac cggcactgct gaaagagctg gcggagagcg aaggggctat cgaacgtaaa
     3421 ctgtcttaca ccggcgaagt gaaagcgcgt ccggcgcgta tcactgagtc cgagttcctg
     3481 tggcagcaca accaggatcc aatggcagta gataaactgg cggaaggtat ccgtaagttt
     3541 gctattgacc aggaaaaact ggaaaaaatg atcggcgatc tgctgtaatc attcttagcg
     3601 tgaccgggaa gtcggtcacg ctacctcttc tgaagcctgt ctgtcactcc cttcgcagtg
     3661 tatcattctg tttaacgaga ctgtttaaac ggaaaaatct tgatgaatac tttacgtatt
     3721 ggcttagttt ccatctctga tcgcgcatcc agcggcgttt atcaggataa aggcatccct
     3781 gcgctggaag aatggctgac atcggcgcta accacgccgt ttgaactgga aacccgctta
     3841 atccccgatg agcaggcgat catcgaacaa acgttgtgtg agctagtgga tgaaatgagt
     3901 tgccatctgg tgctcaccac gggcggaact ggcccggcgc gtcgtgacgt aacgcccgat
     3961 gcgacgctgg cagtagcgga ccgcgagatg cctggctttg gtgaacagat gcgccagatc
     4021 agcctgcatt ttgtaccaac tgcgatcctt tcgcgtcagg tgggcgtgat tcgcaaacag
     4081 gcgctgatcc ttaacttacc cggtcagccg aagtctatta aagagacgct ggaaggtgtg
     4141 aaggacgctg cgggtaacgt tgtggtacac ggtatttttg ccagcgtacc gtactgcatt
     4201 cagttgctgg aagggccata cgttgaaacg gcaccggaag tggttgcagc attcagaccg
     4261 aagagtgcaa gacgcgacgt tagcgaataa aaaaatcccc ccgagcgggg ggatctcaaa
     4321 acaattagtg ggattcacca atcggcagaa cggtgcgacc aaactgctcg ttcagtactt
     4381 cacccatcgc cagatagatt gcgctggcac cgcagatcag cccaatccag ccggcaaagt
     4441 ggatgattgc ggcgttaccg gcaatgttac cgatcgccag cagggcaaac agcacggtca
     4501 ggctaaagaa aacgaattgc agaacgcgtg cgcctttcag cgtgccgaag aacataaaca
     4561 gcgtaaatac gccccacaga cccaggtaga caccaaggaa ctgtgcattt ggcgcatcgg
     4621 tcagacccag tttcggcatc agcagaatcg caaccagcgt cagccagaaa gaaccgtaag
     4681 aggtgaatgc ggttaaaccg aaagtgttgc cttttttgta ctccagcaga ccagcaaaaa
     4741 tttgcgcgat gccgccgtag aaaatgccca tggcaagaat aataccgtcc agagcgaaat
     4801 aacccacgtt gtgcaggtta agcagaatgg tggtcatgcc gaagcccatc aggcccagcg
     4861 gtgccggatt agccaactta gtgttgccca taattcctca aaaatcatca tcgaatgaat
     4921 ggtgaaataa tttccctgaa taactgtagt gttttcaggg cgcggcataa taatcagcca
     4981 gtggggcagt gtctacgatc ttttgagggg aaaatgaaaa ttttccccgg tttccggtat
     5041 cagacctgag tggcgctaac catccggcgc aggcaggcga tttgcagtac ggctggaatc
     5101 gtcacgcgat aggcgctgcc gctgaccgct ttaaccccat ttagtgccgc acctacaggg
     5161 cctcccagcc ccgcgccgcg cagcaaacca tgcccaagta cgctcattgc tgcgtgggtg
     5221 cgtaaaatgc gggtcagttg gctggaaagc aaatgcgaca cgccttttgc caataatttg
     5281 tctttcatca gcagcggcag cagctcttcc agctcattca ccctggcatc gatcgcgtgc
     5341 agaaactcct gcttatgttc ctcgtccata ttcttccagg tgttacgcag aaattgttcc
     5401 agtaactgtt gctcaatctc aaacgtagac atctctttgt cggctttcag cttcaatcgt
     5461 tttgaaacat cgagcaaaat ggcccgatac aatttaccgt gtccgcgcag tttgttggcg
     5521 atactatcgc caccaaaatg ctgtaattct ccagcaatca gctgccagtt gcggcgatgt
     5581 tgctcgggat gcccttccat cgatttaaac agttcgttgc gcatcagtac gctggagagg
     5641 cgagttttgc ctttttcatt atgggtgagc aatcgggcga aatttgccaa ctgttcctca
     5701 ctgcaatgct ggagaaaatc cagatctgaa tcattcaggt aattaacatt cattttttgt
     5761 ggcttctata ttctggcgtt agtcgtcgcc gataattttc agcgtggcca tatccgatga
     5821 gttcaccgta tgaccggaaa aggtgatttt tgagacgcag cgtttattgt cgttatcact
     5881 gttaatgttg atccagtcag tggtttgccc ttcttttatt tctgaaggaa tattcagact
     5941 ctgactggcg ctacgggcgg ctttgaaata aaccgatgca ccgcttaact gtaaatcgcc
     6001 atggtcggca gagagttgta tgcgtttcac aatgcgacaa acaggaagtt tcagcgccag
     6061 atcgttggtt tcgttacgcg gcattgcaat gacgccgagg agtttatggt cgtttgcctg
     6121 cgccgtgcag cacagcatca ggctaatcgc caggctggcg gaaatcgtaa aaacggattt
     6181 cataaggatt ctcttagtgg gaagaggtag agggatgaat acccactagt ttactgctga
     6241 taaagagaag attcaggtac gtaatctttt ctttttatta caattttttg atgaatgcct
     6301 tggctgcgat tcattcttta tatgaataaa attgctgtca attttacgtc ttgtcctgcc
     6361 atatcgcgaa atttctgcgc aaaagcacaa aaaatttttg catctccccc ttgatgacgt
     6421 gggttacgac cccatttagt agtcaaccgc agtgagtgag tctgcaaaaa aatggaattg
     6481 ggcagttgaa accagacgtt tcgcccctat tacagactca caaccacatg atgaccgaat
     6541 atatagtgga gacgtttaga tgggtaaaat aattggtatc gacctgggta ctaccaactc
     6601 ttgtgtagcg attatggatg gcaccactcc tcgcgtgctg gagaacgccg aaggcgatcg
     6661 caccacgcct tctatcattg cctataccca ggatggtgaa actctggttg gtcagccggc
     6721 taaacgtcag gcagtgacga acccgcaaaa caccctgttt gcgattaaac gcctgattgg
     6781 ccgccgcttc caggacgaag aagtacagcg tgatgtttcc atcatgccgt tcaaaattat
     6841 tgctgctgat aacggcgacg catgggtcga agttaaaggc cagaaaatgg caccgccgca
     6901 gatctctgct gaagtgctga aaaaaatgaa gaaaaccgct gaagattact tgggtgaacc
     6961 ggtaactgaa gctgttatca ccgtaccggc atactttaac gatgctcagc gtcaggcaac
     7021 caaagacgca ggccgtatcg ctggtctgga agtaaaacgt atcatcaacg aaccgaccgc
     7081 agctgcgctg gcttacggtc tggacaaagg tactggcaac cgtactatcg cggtttatga
     7141 cctgggtggt ggtactttcg atatttctat tatcgaaatc gacgaagttg acggcgaaaa
     7201 aaccttcgaa gttctggcta ccaacggtga tacccacctg ggtggtgaag acttcgacag
     7261 ccgtctgatc aactacctgg ttgaagaatt caagaaagat cagggcattg acctgcgcaa
     7321 cgatccgctg gcaatgcagc gcctgaaaga agcggcagaa aaagcgaaaa tcgaactgtc
     7381 ttccgctcag cagaccgacg ttaacctgcc gtacatcact gcagatgcga ccggtccgaa
     7441 acacatgaac atcaaagtga ctcgtgcgaa actggaaagc ctggttgaag atctggtaaa
     7501 ccgttccatt gagccgctga aagttgcact gcaggacgct ggcctgtccg tatctgatat
     7561 cgacgacgtt atcctcgttg gtggtcagac tcgtatgcca atggttcaga agaaagttgc
     7621 tgagttcttt ggtaaagagc cgcgtaaaga cgttaacccg gacgaagctg tagcaatcgg
     7681 tgctgctgtt cagggtggtg ttctgactgg tgacgtgaaa gacgtactgc tgctggacgt
     7741 taccccgctg tctctgggta tcgaaaccat gggcggtgtg atgacgacgc tgatcgcgaa
     7801 aaacaccact atcccgacca agcacagcca ggtgttctct accgctgaag acaaccagtc
     7861 tgcggtaacc atccatgtgc tgcagggtga acgtaaacgt gcggctgata acaaatctct
     7921 gggtcagttc aacctggatg gtatcaaccc ggcaccgcgc ggcatgccgc agatcgaagt
     7981 taccttcgat atcgatgctg acggtatcct gcacgtttcc gcgaaagata aaaacagcgg
     8041 taaagagcag aagatcacca tcaaggcttc ttctggtctg aacgaagatg aaatccagaa
     8101 aatggtacgc gacgcagaag ctaacgccga agctgaccgt aagtttgaag agctggtaca
     8161 gactcgcaac cagggcgacc atctgctgca cagcacccgt aagcaggttg aagaagcagg
     8221 cgacaaactg ccggctgacg acaaaactgc tatcgagtct gcactgactg cactggaaac
     8281 tgctctgaaa ggtgaagaca aagccgctat cgaagcgaaa atgcaggagc tggcacaggt
     8341 ttcccagaaa ctgatggaaa tcgcccagca gcaacatgcc cagcagcaga ctgccggtgc
     8401 tgatgcttct gcaaacaacg cgaaagatga cgatgttgtc gacgctgaat ttgaagaagt
     8461 caaagacaaa aaataatcgc cctataaacg ggtaattata ctgacacggg cgaaggggaa
     8521 tttcctctcc gcccgtgcat tcatctaggg gcaatttaaa aaagatggct aagcaagatt
     8581 attacgagat tttaggcgtt tccaaaacag cggaagagcg tgaaatcaaa aaggcctaca
     8641 aacgcctggc catgaaatac cacccggacc gtaaccaggg tgacaaagag gccgaggcga
     8701 aatttaaaga gatcaaggaa gcttatgaag ttctgaccga ctcgcaaaaa cgtgcggcat
     8761 acgatcagta tggtcatgct gcgtttgagc aaggtggtat gggcggcggc ggttttggcg
     8821 gcggcgcaga cttcagcgat atttttggtg acgttttcgg cgatattttt ggcggcggac
     8881 gtggtcgtca acgtgcggcg cgcggtgctg atttacgcta taacatggag ctcaccctcg
     8941 aagaagctgt acgtggcgtg accaaagaga tccgcattcc gactctggaa gagtgtgacg
     9001 tttgccacgg tagcggtgca aaaccaggta cacagccgca gacctgtccg acctgtcatg
     9061 gttctggtca ggtgcagatg cgtcagggtt tctttgccgt gcagcagacc tgtccacact
     9121 gtcagggtcg cggtacgctg atcaaagatc cgtgcaacaa atgtcatggt catggtcgtg
     9181 ttgagcgcag caaaacgctg tccgttaaaa tcccggcagg ggtggacact ggagaccgca
     9241 tccgtcttgc gggcgaaggt gaagcgggcg agcatggcgc accggcaggc gatctgtacg
     9301 ttcaggttca ggttaaacag cacccgattt tcgagcgtga aggcaacaac ctgtattgcg
     9361 aagtcccgat caacttcgct atggcggcgc tgggtggcga aatcgaagta ccgacccttg
     9421 atggtcgcgt caaactgaaa gtgcctggcg aaacccagac tggtaagctg ttccgtatgc
     9481 gcggtaaagg cgtcaagtct gtccgcggtg gcgcacaggg tgatttactg tgccgcgttg
     9541 tcgtcgaaac accggtaggc ctgaacgaga agcagaaaca gctgctgcaa gagctgcaag
     9601 aaagcttcgg tggcccaacc ggcgagcaca acagcccgcg ctcaaagagc ttctttgatg
     9661 gtgtgaagaa gttttttgac gacctgaccc gctaacctcc ccaaaagcct gcccgtgggc
     9721 aggcctgggt aaaaataggg tgcgttgaag atatgcgagc acctgtaaag tggcggggat
     9781 cactccccgc cgttgctctt actcggattc gtaagccgtg aaaacagcaa cctccgtctg
     9841 gccagttcgg atgtgaacct cacagaggtc ttttctcgtt accagcgccg ccactacggc
     9901 ggtgatacag atgacgatca gggcgacaat catcgcctta tgctgcttca ttgctctctt
     9961 ctccttgacc ttacggtcag taagaggcac tctacatgtg ttcagcatat agggggcctc
    10021 gggttgatgg taaaatatca ctcggggctt ttctctatct gccgttcagc taatgcctga
    10081 gacagacagc ctcaagcacc cgccgctatt atatcgctct cttt
//
LOCUS       DAPGUL010000149        10002 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.152, whole genome shotgun sequence.
ACCESSION   DAPGUL010000149 DAPGUL010000000
VERSION     DAPGUL010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10002
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.152"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..184
                     /locus_tag="RHX21_004102"
     CDS             <1..184
                     /locus_tag="RHX21_004102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025307.1"
                     /note="NorM; MdtK; functions as a Na(+)/drug antiporter;
                     inactivation in Vibrio cholerae results in susceptibility
                     to fluoroquinolones; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDV1989219.1"
                     /translation="LGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMR
                     FLQRLPSVIILQRASR"
     gene            complement(225..1481)
                     /locus_tag="RHX21_004103"
     CDS             complement(225..1481)
                     /locus_tag="RHX21_004103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIDA repeat-containing protein"
                     /protein_id="HDV1989220.1"
                     /translation="MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENT
                     VVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRH
                     PEGEFSVDQGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGE
                     LLVYPGGEASNCEINQGGVFMLAGKASDTLLAGGTMNNLGGEDSDTIVENGSIYRLGT
                     DGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRA
                     PVELTGSVALLDGASMIIGYGADLQQSTITVQQGGVLILDGSTVKGDGVTFIVGNINL
                     NGGKLWLITGAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIHVEITD
                     ASRQTLCNALKLQPDEDGIGATLQPA"
     gene            1789..1865
                     /locus_tag="RHX21_004104"
     tRNA            1789..1865
                     /locus_tag="RHX21_004104"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1823..1825,aa:Val,seq:gac)
     gene            1870..1946
                     /locus_tag="RHX21_004105"
     tRNA            1870..1946
                     /locus_tag="RHX21_004105"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1904..1906,aa:Val,seq:gac)
     gene            2054..2359
                     /locus_tag="RHX21_004106"
     CDS             2054..2359
                     /locus_tag="RHX21_004106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HDV1989221.1"
                     /translation="MATLLQLHFAFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTES
                     EKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNEPLSQINQAKLA"
     gene            2485..4089
                     /locus_tag="RHX21_004107"
     CDS             2485..4089
                     /locus_tag="RHX21_004107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-NAD(P)-binding protein"
                     /protein_id="HDV1989222.1"
                     /translation="MKKIAIVGAGPTGIYTLFSLLQQQTPLSISIFEQADEAGVGMPY
                     SDEENSKMMLANIASIEIPPINCTYLEWLQKQEASHLQRYGVKKETLHDRQFLPRILL
                     GEYFRDQFLRLVDQARQQKFAVAVYESCQVTDLQITNAGVMLATNQDLPSETFDLAVI
                     ATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFI
                     EDDKQHVVFNRDNASEKLNITLMSRTGILPEADFYCPIPYEPLHIVTDQALNAEIQKG
                     EEGLLDRVFRLIVEEIKFADPDWSQRIALESLNVDSFAQAWFAERKQRDPFDWAEKNL
                     QEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPS
                     ESIRRLLALREAGIIHILALGEDYKMEINESRTVLKTEDNSYSFDVFIDARGQRPLKV
                     KDIPFPGLREQLQKTGDEIPDVGEDYTLQQPEDIRGRVAFGALPWLMHDQPFVQGLTA
                     CAEIGEAMARAVVKPASRARRRLSFD"
     gene            complement(4101..4913)
                     /locus_tag="RHX21_004108"
     CDS             complement(4101..4913)
                     /locus_tag="RHX21_004108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989223.1"
                     /translation="MIITRADLREWRIGAVMYRWFLRHFPRGGSYADIHHALIEEGYT
                     DWAESLVEYAWKKWLADENFAHQEVSSMQKLATDPGEIPFCSQFARSDDHARIGCCED
                     NARIATAGYAAQIASMGYSVRIGSVGFNSHIGSSGERARVAVTGNSSRISSAGDSSRI
                     ANTGMRVRVCTLGERCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTG
                     VVDSIILGPGGSAALAYHDGERVRFAVAIEGENNIRTGVRYRLNEQHQFVEC"
     gene            complement(4917..5702)
                     /locus_tag="RHX21_004109"
     CDS             complement(4917..5702)
                     /locus_tag="RHX21_004109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate reductase cytochrome B subunit"
                     /protein_id="HDV1989224.1"
                     /translation="MNPSQHAEQFQSQLANYVPQFTPEFWPVWLIIAGVLLVGMWLVL
                     GLHALLRARGVKKSVTDYGEKIYLYCKAVRLWHWSNALLFVLLLASGLINHFALVGAT
                     AVKSLVAVHEVCGFLLLACWLGFVLINAVGGNGHHYRIRRQGWLERAAKQTRFYLFGI
                     MQGEEHPFPATTQSKFNPLQQVAYVGVMYGLLPLLLLTGLLCLYPQAVGDVFPGVRYW
                     LLQAHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH"
     gene            complement(5699..6367)
                     /locus_tag="RHX21_004110"
     CDS             complement(5699..6367)
                     /locus_tag="RHX21_004110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416186.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HDV1989225.1"
                     /translation="MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKEVRYAMIHDES
                     RCNGCNICARACRKTNHVPAQGSRLSIAHIPVTDNDNETQYHFFRQSCQHCEDAPCID
                     VCPTGASWRDEQGIVRVEKSQCIGCSYCIGACPYQVRYLNPVTKVADKCDFCAESRLA
                     KGFPPICVSACPEHALIFGREDSPEIQAWLQQNKYYQYQLPGAGKPHLYRRFGQHLIK
                     KENV"
     gene            complement(6431..7069)
                     /locus_tag="RHX21_004111"
     CDS             complement(6431..7069)
                     /locus_tag="RHX21_004111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707570.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdhW family putative oxidoreductase system
                     protein"
                     /protein_id="HDV1989226.1"
                     /translation="MNHRDELPLAKVSEVDEAKRQWLQGMRHPVDTVTEPEPAEILAE
                     FIRQHSAAGQLVARAVFLSPPYSVAEEELSVLLESIKQNGDYADIACMTGSQDDYYYS
                     TQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEA
                     AIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP"
     gene            complement(7082..9184)
                     /locus_tag="RHX21_004112"
     CDS             complement(7082..9184)
                     /locus_tag="RHX21_004112"
                     /EC_number="1.2.7.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016246021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde ferredoxin oxidoreductase"
                     /protein_id="HDV1989227.1"
                     /translation="MANGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDE
                     VPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQ
                     MKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCV
                     AAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKR
                     LNDYMMTELIGANNNHVVPSTPQSWAEYSDPKSRWTARKGLFWGAAEGGPIETGEIPP
                     GNQNTVGFRTYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPSTGGN
                     TCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYS
                     KGVFKRVLPAEEYAEIRWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAERWN
                     LGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPL
                     KLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTV
                     SPLKSRNYRGDLALEAKFFKAITGEEMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRN
                     EHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQR
                     LGLEDIAADLAAHNLLPV"
     gene            complement(9205..9831)
                     /locus_tag="RHX21_004113"
     CDS             complement(9205..9831)
                     /locus_tag="RHX21_004113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like protein"
                     /protein_id="HDV1989228.1"
                     /translation="MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQE
                     DIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFG
                     DNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQKEGCITVDHKRCIGCS
                     ACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV"
BASE COUNT         2542 a         2660 c         2240 g         2560 t
ORIGIN      
        1 gctgggcttg ccaagcggct atattctggc actgaccgat ctggtcgttg aacctatggg
       61 gccagcaggc ttctggatag gctttattat tggcctgacg tcggcagcca ttatgatgat
      121 gctgcgtatg cggttcctgc aacgtctgcc gtcagttatc attctgcaac gagcatcccg
      181 ctaataaaga caaggcgcaa ccttcacggg ttgcgcctgt gtttttacgc aggctggagc
      241 gttgcgccaa tcccgtcttc gtctggctgt aatttcagag cgttgcacag agtttgccga
      301 ctggcatctg ttatctcaac gtgtatatcc ccggtaactt cccctttcac attgatgaag
      361 tcaggtgaga tttctttcgc actggtttgc aggcaaatcg ctccctctcc gcgcaggcgt
      421 ttcactttca gttgcacatg cgttgccgca ccagtgatca gccacagttt tccgccattc
      481 agattgatgt taccaacaat aaaagtgaca ccgtcacctt ttaccgtact gccgtcgaga
      541 atcaacacac cgccctgctg tacagtaatc gttgattgtt gcagatctgc gccatagcca
      601 ataatcattg aagcgccgtc cagtaatgca acactcccgg tcagttcaac cggtgcacga
      661 tcttcctcta cgacaaaatt ttcgtccgcg ctggtgggtg acaacaggat cactgttcca
      721 ccttgtatta ccgcattttc cagcgtaccg gcatgcactt cagcccgacc acccacattc
      781 acggacaggt tttgcgtctt accggaactg tagagctgaa ggccatccgt ccccagacga
      841 taaatggatc cattctcaac aatagtgtca gagtcttcac caccgagatt attcatggtg
      901 ccaccagcaa gcaacgtatc actggctttc ccggccagca taaaaacgcc gccctgatta
      961 atctcacaat tgctggcttc cccacctgga tacaccaaca attcaccacc ttcatctacc
     1021 acgaccgctg aggttgtccc attaaccaac aggccgccct cttgatcgag aatgattttt
     1081 tccgcgcgat gtccttccag tacacgcagg ttaccgccat tttccagcaa caaaccgcag
     1141 gcataaccct gatcaacgct gaattcacct tcgggatggc ggccattaac cgtagcgagc
     1201 gtagagagac taattgcgcc tccctcggac tgaacaatat ctgtggcaat ggcaccgtcg
     1261 ctgaccgata gcgtgccatt gttaccgtac tgtgtgcatt tggcgatccc accggttgcc
     1321 actttcaacc agccagcccc cgtgaccacg gtattttcgg ctcttccgcc agcttcaaca
     1381 atcaactcgc cttcagtaag ttgcgtcgcg ccaatgacct cgccggtctt aacaatttgc
     1441 acattcccgt cgctcatcaa gtttttcgca tcagatccca tgatttattc ctttgctgca
     1501 tctgtgtgcc tttattgcta cctaagtgta aaggctacgg aggatttatc cacgacagat
     1561 ttgagatggt ggcaaacaac tctgtttaaa ctctgataca cgaattattg ggttgtatca
     1621 gatgtaaatg cgatcctgaa taaaaatcgc ccttgcaaat caacaaaata tagccaattt
     1681 gcttaaaagc tctgcaaacg gtcgaaatag cgcagaaaat tacgttttgc ctcttgccac
     1741 cttcccactc tgccgctaat attcgtcccc gttgtcacct acaacgttgc gttcatagct
     1801 cagttggtta gagcaccacc ttgacatggt gggggtcgtt ggttcgagtc caattgaacg
     1861 caccatcctg cgtccgtagc tcagttggtt agagcaccac cttgacatgg tgggggtcgg
     1921 tggttcgagt ccactcggac gcaccagatt ttcttaatct ggtcttctcc tttttccctc
     1981 tgtttcttct ctgtatccaa tacgttaaaa gatttacact gtcttcgtat gcgttatcag
     2041 aaggagaatc gctatggcaa ctttgttaca acttcatttt gcttttaatg gcccatttgg
     2101 cgacgcaatg gctgagcagc ttaaaccgct tgctgagtcg attaatcagg aacctggttt
     2161 tctgtggaag gtatggacag aaagtgaaaa gaaccacgaa gccggtggga tctatctttt
     2221 tactgatgaa aaaagcgccc ttgcctatct ggaaaaacat actgcccgac ttaaaaatct
     2281 cggcgttgag gaagttgtcg ccaaagtttt cgatgtcaat gagccactga gtcaaatcaa
     2341 tcaggcaaaa ctcgcctgac agaatttaat caagggcggt tagcgccctt ttcatccctg
     2401 tctgaaattt ctcaaattct aaaaatctca accaaactta tctgataaca ctaaattcga
     2461 aagaatgcgt acaggtaagt aacaatgaaa aaaattgcta ttgtgggtgc cgggcctacg
     2521 gggatctaca ccttattctc gcttctacag caacaaactc cactttctat ttctatcttc
     2581 gagcaggctg acgaggccgg tgtcgggatg ccatacagtg atgaggaaaa ctcaaaaatg
     2641 atgctggcaa atattgccag tattgaaata ccgccgatta attgtacgta tctcgaatgg
     2701 ctacaaaagc aagaagccag ccatctccag cgttatggcg ttaaaaaaga aaccttgcac
     2761 gatcgtcagt ttttaccgcg aattctgctg ggcgaatatt tccgcgatca atttttacga
     2821 ttagtagacc aggcacgaca gcaaaaattt gcagtggctg tttatgaatc atgccaggtt
     2881 accgatctgc aaattacaaa tgctggcgtc atgctcgcta caaatcagga tttacccagc
     2941 gagacgtttg atttagcggt gattgccacg ggtcacgtct ggcctgatga agaagaagca
     3001 accagaacgt attttcccag tccgtggtca ggcctgatgg aagcaaaggt cgatgcgtgt
     3061 aacgtgggta ttatgggaac atccttgagc ggactggatg cggcaatggc agtggctatt
     3121 cagcatggtt cgttcattga agatgataaa caacacgtcg tttttaaccg cgataacgca
     3181 agtgaaaagc taaatattac gttgatgtcg cgcacgggta ttttacccga agccgatttc
     3241 tattgcccta ttccctacga gcccttacac atcgtcaccg atcaggcatt aaatgctgag
     3301 attcaaaaag gtgaagaggg ccttttggat cgggtattta gattgatagt agaggaaatc
     3361 aagtttgctg atccagactg gagccaacgc atagccttag agagcctgaa tgtcgattcc
     3421 tttgctcaag cctggtttgc cgagcgcaaa caacgcgacc catttgactg ggcagaaaaa
     3481 aatctccagg aagtcgaacg caataaacga gaaaaacata ctgttccctg gcgttatgtc
     3541 attctgcgcc tgcatgaagc cgtacaggaa attgttcctc atctgaatga acacgaccat
     3601 aaacggttca gtaaaggcct tgccagggtt ttcatcgata attatgcggc aatcccttca
     3661 gagtctattc gtcgcctact tgccttacgt gaagcgggaa tcattcatat tctcgccctc
     3721 ggtgaagact acaaaatgga aattaatgag tcgcgcaccg tcctgaaaac ggaagacaac
     3781 agctactcgt ttgacgtttt tattgatgcc cgcggacagc gtccgcttaa agtgaaagat
     3841 attcctttcc ctgggctacg cgagcaatta cagaaaacag gggatgaaat ccctgatgtt
     3901 ggcgaagatt atacgttaca gcaacccgaa gatattcgtg gacgcgtagc gttcggcgcg
     3961 ttgccctggt tgatgcacga ccagcctttc gttcagggac ttacggcatg tgcagaaatt
     4021 ggtgaggcga tggctcgggc ggtcgtaaag cctgcatccc gtgctcgtcg gcgtctttcg
     4081 tttgattaaa ggtaaagcta tcagcactca acaaactgat gctgttcatt aagacgatag
     4141 cggactccgg ttcgaatatt gttttcacct tcaatggcga cggcgaagcg aactctttcg
     4201 ccgtcatgat atgccagtgc ggcgcttccc cctggcccga gaataattga gtcgaccacg
     4261 cccgtgctca ctaccgttga attttcaccg ctggcaatga tgtgtacatt gtcgccgctg
     4321 ttggcaattc tggcgtttgc gccaaagctg gcgatttgca ccaggtcacc attactggcg
     4381 acatgacacc gttcacccaa tgtacaaacg cgtactcgca ttccggtatt cgcaatccga
     4441 ctactatctc cagcgctgct tatccgcgaa gaattaccgg ttacagcaac ccgtgcgcgt
     4501 tcaccggagc tgccaatgtg actgttaaag ccgacacttc caatccgcac gctataaccc
     4561 atactggcaa tttgcgcggc atacccagcg gttgcgattc gggcgttatc ctcacaacag
     4621 ccgatgcgag catgatcgtc gctgcgggca aactgactgc aaaatggtat ctctccgggg
     4681 tctgtggcca gtttttgcat agaggaaact tcctgatgcg cgaagttttc atccgccagc
     4741 cattttttcc acgcatactc aaccagactc tccgcccagt ccgtatatcc ttcctcaatc
     4801 agtgcatgat gaatatcggc ataactaccg ccgcgtggga aatggcgcag gaaccagcga
     4861 tacatcaccg ctccgatacg ccattctcgc aggtctgctc gtgtaatgat cattcgttag
     4921 tgccggtgat agccatcgac catgctttta aaggtttcgt gtggcgtacg ccccgtggtg
     4981 caaagataaa gatgaccgaa gataaaaaag aggcttataa atgccagagc aaaatgcgcc
     5041 tgcaataacc agtatcttac gccaggaaac acatctccca cagcttgcgg atagagacac
     5101 agcagccccg tcaatagtaa caacggcagc aatccataca taacaccaac ataggcgacc
     5161 tgctgtaagg gattaaattt agactgggtt gttgccggga aaggatgttc ttccccctgc
     5221 ataatgccaa acaaataaaa tcgcgtttgt tttgccgctc gctccagcca cccctgacga
     5281 cgaatgcgat agtggtgacc attaccccca acggcattga tcagcacaaa gccgagccag
     5341 catgcgagta acaaaaatcc gcaaacttca tgcaccgcaa ccagactttt aaccgcagtt
     5401 gcgcccacca gcgcaaagtg atttatcagc ccacttgcca gcaacaatac aaagagtaac
     5461 gcattcgacc agtgccataa tctgaccgct ttgcagtaaa gataaatctt ctcaccataa
     5521 tcggtgactg atttcttcac gccacgagca cgaagcaagg catgcagccc cagcaccaac
     5581 cacatcccaa ccagcaatac tccggcaatg atcaaccaca ccggccaaaa ttcgggagtg
     5641 aactgtggca catagttcgc taactggctc tgaaactgtt cagcatgttg cgacgggttc
     5701 atacattttc ctttttaatc aaatgttgac cgaaccggcg atacagatgc ggtttcccgg
     5761 caccaggtag ctgatattga tagtatttat tttgctgcaa ccacgcctga atttctgggc
     5821 tatcttcgcg accaaagatc aatgcgtgtt ccgggcaggc gctgacgcaa atgggcggaa
     5881 agccttttgc cagtcgggac tcagcgcaga aatcacattt atctgccact ttagtgacag
     5941 ggttaaggta gcgaacctgg tacggacaag cgccaatgca ataactgcag ccgatgcact
     6001 gcgatttttc tacccgcacg atcccctgct catcacgcca cgacgcccct gtcgggcata
     6061 cgtcgatgca cggagcatct tcgcagtgct gacatgactg gcgaaaaaag tgatactgcg
     6121 tttcgttatc gttatcggtg actggaatgt gtgctatcga taaacggctt ccctgagcgg
     6181 ggacgtggtt agttttacgg catgcgcggg cgcaaatatt acagccattg caccgtgact
     6241 cgtcatgaat catggcatac cgaacttcct tttcttgcct cgtgttcgct aacagagaag
     6301 acgcagaacc agtaaaaaag attactgttc ccatccccag aacaaatttg cgtcgagtga
     6361 aggacatctg attatcccct aatgcagtgg ctgcaactgt ccaccctatc catgacatct
     6421 ccctgaaatt tcaggggttc tgaaactgct ctacctcgaa ccattcgcat aagccataag
     6481 ccttgccata ggtcataaat cgctcgctaa acaagtacaa caccgccgtc gatgactcca
     6541 cctgccgtat atcggcatat tcaggtgcaa catccatcgc ggcgatcgcg gcttcaatct
     6601 gcgcttcctg gaagtaatat ggcgcttgca tcagcatggc gactttgtaa ggacgaggat
     6661 atgtctggca ctcaaaacga acggcgtgtg caatggcgcg acaaatgtcc tgctccacaa
     6721 cttgcaaaga catcgccgcg tagttttcac tcatggcctg cgttgagtaa tagtaatcat
     6781 cctgacttcc cgtcatacaa gcgatatccg cgtagtctcc gttctgctta atgctttcca
     6841 gcaaaactga cagctcctct tctgcaaccg aatagggtgg cgagagaaac acggcgcgcg
     6901 ccaccagctg cccagccgca gaatgctggc gaatgaactc tgccaggatt tcagccggtt
     6961 ctggttcggt taccgtatca acggggtgac gcatcccctg taaccattgc cgcttcgcct
     7021 cgtcaacttc gctgactttc gctaacggca attcatcccg atggttcatc tcacccattc
     7081 cttacacagg cagtagattg tgtgctgcca gatcggcggc aatatcttcc agccccagac
     7141 gctgcaatgt ttcgcgggtc ggacaaccaa gctgtgggtc ccagcccatt tctttgtaga
     7201 acatcgtgag cgaagcatgc atatcgtcac gatccatttt gtcagtacct tcagtaaaga
     7261 ccgggatctg cggatccttg tcgaataccc aggaacagat aagatcgtgt tcattacgca
     7321 tatctttggt ttgcatcagt tttaccgtgt aggcacgatg caacgtaaag atacgctctg
     7381 cagctaaatc taatttttcc tgagtcatct cttcgccggt gatcgctttg aagaatttgg
     7441 cttcaagcgc cagatcgccc cggtaattac ggcttttcag cggcgaaacg gtcattggcc
     7501 agacccagtt gcacagggtg acggcgttat gcaaacagac ccgcaacagc gaccactttg
     7561 catatttaat ttttgcgtca ttgattggcg tgtagttttt ggtttcatcg taggcatctt
     7621 cagaaccaaa aagctctttc gccacttcac gctgcagttt caatggcaaa cccgaaccaa
     7681 taaaattgat atgggtatgc gtcatgcagt cacggttgaa catacagtta acaatggaac
     7741 cgacctgcgc tgacgcttca ttggcatggt gaaccggata gccaaacggc gaccagagtt
     7801 tatttttcgc gtagccccag tactcttcac ccaaattcca gcgttctgcg atggcatatg
     7861 aaccatcagc caggtgactc agctcaccca cacgatgcgc cagacggtag taaaaatctt
     7921 taatgaagtt aacgtcaccc gcttccagtt gatcccagcg aatttccgca tactcttcag
     7981 caggcagaac acgcttgaac acccctttgc tgtaacaata ggtaaagtcg cgatgcaact
     8041 gcccgtagtt acaccatagg ccgtagtcat cgaacaaatt cagacccacc aggttaccaa
     8101 tcacacgacc atcgtcttta tcttcaaaat ctttcggccc gttcgggaag atggtggtat
     8161 ggacaaagtt ggctacacaa gtgttaccac ctgtgctggg cacgccaaac tctttcaccc
     8221 gaggaatatt catttgggtc atacaacgga tcgggcaaga gtggcagcca ctcattttta
     8281 ctgtgtattt ctctgccgcc ggacctaagt caaaaacgga tttataggta cgaaagccga
     8341 ccgtgttctg attgcctggc ggaatttccc ccgtttcaat cggaccacct tcagccgcgc
     8401 cccaaaacag ccctttacgt gctgtccaac gtgacttggg atctgaatac tctgcccacg
     8461 attgcggcgt acttggcacg acatggttgt tattcgcacc aataagttca gtcatcatgt
     8521 aatcgttgag acgcttcatc tcctgacgat cggcaatgtt gacccctttc gtcccttcaa
     8581 ccgcaatcgc tttcaggttt ttcgaaccca taattgcgcc agttcccgca ccgccgctgt
     8641 ggttacggct attcaacatg ccagagagag gaacaaggtt ttccccagcc tgaccaatag
     8701 ccgccacaca ggtttccgga ctggtcaatc gacaaatttc ttccgtcgtt gcgcgcgtcc
     8761 cttttcccca taagaaatcg gctttttcca ggctaacttt gtcatcttta atcttcagcc
     8821 ataccggtga tttcgccttc ccttcgataa taatgacgtc gtatccagcg aatttcattt
     8881 gcgctgcaaa aaagccaccc atatgggcat cgacaactaa atttcctttg gtaaaagtag
     8941 aaagtgaggt gatatttacg cgagaactac agggggcacc agatccagtt aatgggccgg
     9001 tagcaaagac taatttattc gcttcatcga aaggtttcgt gcctggcggt acttcgtcat
     9061 acataatttt gtagccgaag cccatgccac cgacaaaact tttaaactta ctggaatctt
     9121 cgagggtaat atttcctgtc gtgagattga ctcttaatat attacctgtc caaccgttag
     9181 ccatgatttt ttcctttgca agattcacac agtaatatct ttccactcga taatttttaa
     9241 cgcccctgtt gggcaggcgt ttgcgcattc accgcataac acacatttcg aggatttttt
     9301 actttcggta tttacggtgg ccatcatcca cgggcatgcc gtagtacagg cgctacagcc
     9361 aatacagcgt ttatgatcga cggtaataca gccttctttc tgctgccagg taatcgcacc
     9421 aatcgggcag acgttcatgc attgcggctc tttgcattga cggcaggtgt ccgcggtata
     9481 gttgagatcg ccatacaggc cgccgccaga gccaaccccg ttgtcgccaa agaaataatt
     9541 acgatggatt ttgatacggg agaagaatgt ccctactgag ccatcgttga agttggtaca
     9601 agagatttca cagcggtggc aacccgtgca tcgcgctcgc tgggtcacca gcaccccttt
     9661 gggtgtattt atcaacccta ctgtgccgct atcaatatct tcctgtttgc aacccaaaag
     9721 tgacagtaac gcaggggcaa ttgttagacc agcaaggcct tttcctgata tacgcaagaa
     9781 ttctaatcgc gttaagccaa tatctaatag tggacgatca accgggttca tttatttcgc
     9841 atcctcttcg caaacacagt gctgacaatt cagcagcctg atattaagca ttcaactaat
     9901 acgctgctga ctctgtcccc aacaccagat attttcccta acccgatagt gtatgagaaa
     9961 agatttaacg ccgataaact aatcctttat ggttaggaga aa
//
LOCUS       DAPGUL010000150         9894 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.153, whole genome shotgun sequence.
ACCESSION   DAPGUL010000150 DAPGUL010000000
VERSION     DAPGUL010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9894)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9894)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9894
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.153"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..253)
                     /locus_tag="RHX21_004114"
     CDS             complement(<1..253)
                     /locus_tag="RHX21_004114"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989229.1"
                     /translation="MIDYISQLPLPVDQIPQGLKDLLSIEDITNPQKEVIVTHRYEKN
                     LFKDNHECAHMTMATVPQEDINNIKVLQESTNGLVSFSTP"
     gene            complement(576..1754)
                     /locus_tag="RHX21_004115"
     CDS             complement(576..1754)
                     /locus_tag="RHX21_004115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001515619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase"
                     /protein_id="HDV1989230.1"
                     /translation="MAARPRKKEYRHLPDYLIFDKDRGVYKFTLITGKKKNIGKDRAI
                     AIAIAREYNLRMRPELSPSVDNLIRESGGVIGEAKPFAEHVDHIMTRIIEDERPSQST
                     LDDWKNDALRVKAFFVNVPACDIALEHVNTYINKYHACASANVQNRKVSFLKKLFSYA
                     VDESLMLDNPAIRKKMRRTDEKKRRRLSLEHFIAIRQAAAPWLRTAMDLALQTTHARL
                     EVSRIRYSIREPKDGICGCVWFEQPQNGIYGTLYIHRQKVQKKEASHVAIPIGEELKR
                     IIDDSRDNVASPFVVHRIPERQVKRSKEVSHPTQVAPDYLSRSFSATRDKLGLCDNLP
                     IDERPTFHEIRALAAYLFDQQGIDPQARMAHSDSKSTKIYTQNHIDWVVVPHGEIKAS
                     "
     gene            complement(1757..1966)
                     /locus_tag="RHX21_004116"
     CDS             complement(1757..1966)
                     /locus_tag="RHX21_004116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004123007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989231.1"
                     /translation="MAKLMKASQWGRREFSNGSIPDNRTIKRWVENGLLMGRIVDGSV
                     FVCETEKWGVDSMVSQAVRKLINEG"
     gene            complement(2028..2243)
                     /locus_tag="RHX21_004117"
     CDS             complement(2028..2243)
                     /locus_tag="RHX21_004117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001331173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989232.1"
                     /translation="MSVIKTHTGIVITRDGEKRMKLHSTETSWVVGRCESYDKKTGYR
                     WGAPNMRRRLLLDSIRPIKQVATREQN"
     gene            complement(2240..2426)
                     /locus_tag="RHX21_004118"
                     /pseudo
     CDS             complement(2240..2426)
                     /locus_tag="RHX21_004118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001242743.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2865..3359
                     /locus_tag="RHX21_004119"
     CDS             2865..3359
                     /locus_tag="RHX21_004119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989233.1"
                     /translation="MTRDDYKFYIHYSYVLEKMNYTLLTRIDKLITLMLIVLGFSVFA
                     PYSNLFIFGLFVAVLSVLQLVYQFGQEAGMSKEQARHYKRLLIESDTLSEDQLQARYL
                     KIQDTDSNPWKSLERAAFIRACIFAGVPTKYDLTTKEKFIAWCAGDLPLENELTDIND
                     DQQA"
     gene            complement(3702..4376)
                     /locus_tag="RHX21_004120"
     CDS             complement(3702..4376)
                     /locus_tag="RHX21_004120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional repressor"
                     /protein_id="HDV1989234.1"
                     /translation="MKTIHDIRRSNARKLRDGVGGNSSFATMIDREPTQTSRFMGDGA
                     TKNIGDSMARHIEKCFDLPVGWLDQEHQTTNITKKPDVSITNKQITLVPVISWVQAGA
                     WKEVGYSEVDLSTAETYPCPVPCGEMTYILRVIGDSMIDEYRPGDMIFVDPEVPACHG
                     DDVIALMHDTGETTFKRLIEDGTQRYLKALNPNWPEPYIKINGNCSIIGTVIFSGKPR
                     RYKIKA"
     gene            4467..4667
                     /locus_tag="RHX21_004121"
     CDS             4467..4667
                     /locus_tag="RHX21_004121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415664.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDV1989235.1"
                     /translation="MKAYWDSLTKEQQGELAGKVGSTPGYLRLVFNGYKKASFVLAKK
                     LEQCTSGAITKSDLRPDIYPKD"
     gene            4711..5262
                     /gene="ymfL"
                     /locus_tag="RHX21_004122"
     CDS             4711..5262
                     /gene="ymfL"
                     /locus_tag="RHX21_004122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415665.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YmfL"
                     /protein_id="HDV1989236.1"
                     /translation="MGKHHWKIEKQPEWYMKAVRKTIAALPGGYAEAADWLDVTENAL
                     FNRLRADGDQIFPLGWAMILQRAGGTHFIADAVAQSANGVFVSLPDVEDVDNADINQR
                     LLEVIEQIGSYSKQIRSAIEDGVVEPHEKTAINDELYLSISKLQEHAALVYKIFCISE
                     SNDARECAAPGAVACRDCGETNA"
     gene            5438..5617
                     /locus_tag="RHX21_004123"
     CDS             5438..5617
                     /locus_tag="RHX21_004123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001761574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4222 domain-containing protein"
                     /protein_id="HDV1989237.1"
                     /translation="MRQVNRWFKDHYGVPVRVIRWEPETQRVIYLREGYEHECFSPLE
                     QFRRKFREIEVGHEH"
     gene            5607..6548
                     /locus_tag="RHX21_004124"
     CDS             5607..6548
                     /locus_tag="RHX21_004124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000104949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDV1989238.1"
                     /translation="MSTKLTGYVWDGCAASGMKLSSVAIMARLADFSNDEGVCWPSIE
                     TIARQIGAGMSTVRTAIARLEAEGWLTRKARRQGNRNASNVYQLNVAKLQAAAFSQLS
                     DSDPSKSDASKSDPSKFDASKSGKKAGFHPSESGGDPSVKSKHDPSDKKNSRPDASQP
                     DTQMDEQDFLTRHPDAVVFSPKKRQWGTQDDLTCAQWLWKKIIALYEQAAECDGEVVR
                     PKEPNWTAWANEIRLMCVQDGRTHKQICEMYSRVSRDPFWCRNVLSPSKLREKWDELS
                     LRLSPSVSTYTEKREDPYFKSSYDNVDYSQIPAGFRG"
     gene            6545..7039
                     /locus_tag="RHX21_004125"
     CDS             6545..7039
                     /locus_tag="RHX21_004125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PerC family transcriptional regulator"
                     /protein_id="HDV1989239.1"
                     /translation="MIMSLLNDVQKFIEAHPGCTSGDIADAFAGYSRQRVLQSASKLR
                     QSGRVAHRCEGDTRRHFPRLTERAQELEPQPVRETRSVRNFYVGTNDPRVILCLTRQA
                     EKLESRGLYRRAATVWMAAFRESHSQPERNNFLARREQCLRKSSKRAVSSDEWYLSGN
                     YVGA"
     gene            7039..7365
                     /locus_tag="RHX21_004126"
     CDS             7039..7365
                     /locus_tag="RHX21_004126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003878599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HDV1989240.1"
                     /translation="MTTLTQCQQQVLDMLISYQKERGFPPTNQEVATMLGYRSVNAAV
                     EHLRALEKKGVITIKRGVARGITLHTAVKDDDSEAVGIIRALLAGEENARLRATHWLH
                     ERGLKV"
     gene            7362..7751
                     /locus_tag="RHX21_004127"
     CDS             7362..7751
                     /locus_tag="RHX21_004127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HDV1989241.1"
                     /translation="MKLILPFPPSVNTYWRHPNKGAFAGKSLISAAGRKFQSAACAAI
                     VEQLRRLPKPTSAPASVEIVLFPPDNRIRDLDNYNKALFDALTHAGVWEDDSQVKRML
                     VEWGPVIPEGKVEITISKYEKTAGAAA"
     gene            7771..8568
                     /locus_tag="RHX21_004128"
     CDS             7771..8568
                     /locus_tag="RHX21_004128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KilA-N domain-containing protein"
                     /protein_id="HDV1989242.1"
                     /translation="MNNLMVIDGIEVRRDAYGRYSLNDLHRAAGSLDKHKPAFWLRNE
                     QTERLISELQICNSVNIEPVNVIRGGNNQGTYVCKELVYAYAMWISPSFHLKVIRTFD
                     MVTSAPEKLSGQAADKMQAGVILLDFMRRELNLSNSSVLGACQKLQEAVGLPNLAPRY
                     AIDAPADAHDGSSRPTLSLSALLKQYGIRLTANQAYHQMVKLGIVEQRERYSRTAINN
                     IKKFWSLTAKGCMFGKNITSPANPRETQPHFFESRFPELLKLLDTVH"
     gene            8576..9565
                     /locus_tag="RHX21_004129"
     CDS             8576..9565
                     /locus_tag="RHX21_004129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001764249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF968 domain-containing protein"
                     /protein_id="HDV1989243.1"
                     /translation="MRALLTPEIAPRMGIVLFRPGSELMPLFMQGRVLLEPEPERYSS
                     FASGAVPAASQPLADDPAVRAVFRNEAVIRRAGGVECLESWLLREKGCQWPHSDWHSE
                     NMTTTRHAPGAIRLCWHCDNQLRDQFTERLESMATDNCARWVLSVVRRDLGFDDSHVV
                     TMPELCWWLVRNDLADALPESAARKALRLPKPVVPSVTRESDLVPSVPATSIIQDKAK
                     KVLALKVDPESPESFMLRPKRRRWVNEKYTRWVKTQPCACCGKPADDPHHLIGHGQGG
                     MGTKAHDLFVLPLCRKHHDELHADTVAFEEMYGSQLELIFRFIDRALAIGVLA"
     gene            9583..>9894
                     /locus_tag="RHX21_004130"
     CDS             9583..>9894
                     /locus_tag="RHX21_004130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein"
                     /protein_id="HDV1989244.1"
                     /translation="MRDMYEVMDRWGAWAASDNSGVDWQPVAAGFKGLLPHGKKSRIQ
                     CDDDEGIMIDSCVARLRKYRPEEYELIIAHFVIGISLRTIAKKRKCSDGTIRKKLQAA
                     LG"
BASE COUNT         2518 a         2259 c         2486 g         2631 t
ORIGIN      
        1 caggagtcga aaatgaaact aaaccattag tagactcctg gagaactttg atattattga
       61 tatcttcttg tggtacggta gccattgtca tatgagcaca ctcatgatta tctttaaaaa
      121 gatttttttc gtatctatgt gtgacaatga cctctttctg tggattagta atatcctcta
      181 tagataataa atctttaaga ccttgaggga tctgatctac tggtaaaggt aattgtgata
      241 tatagtcaat cattataatt tatgccttct atgctcagta ttaaattaaa tattaaatcg
      301 aagtcatccc cttggcaacc taaatcgttt gctgctagta cttcagtgta agattaatta
      361 tgcaatagtt tgcaattgaa atatcttaag ctgtagaaaa atcaatcata ctgatacctt
      421 ttacttaagt ttcactccta ggcatgatga acgcttcctc aagatacagt attacgctat
      481 gcctgcaact ttcacttgtg gcatagtaaa cctttcaatt taggtttagc cctgtatagt
      541 agtaatgcac gcttcaaatc tgagctaata aaattttaac tggctttaat ttctccatgt
      601 ggtacgacaa cccaatcaat atggttttgc gtataaatct tggttgactt ggagtcgctg
      661 tgcgccattc gtgcttgcgg atcgatacct tgctgatcga aaagatacgc tgctaatgct
      721 ctaatttcgt gaaaggttgg tctttcatct atcggtagat tgtcgcataa acctagcttg
      781 tcacgtgtgg ctgaaaacga ccggctcaaa tagtccggtg caacttgagt agggtgtgaa
      841 acctctttgc tgcgtttaac ctgccgttca gggatcctgt gaacgacaaa cggactggcc
      901 acattatctc ggctatcatc aattattcgt ttcaactctt caccaatcgg tattgcaacg
      961 tgtgatgcct cttttttttg cactttttgc ctgtggatgt aaagcgtccc atatatgcca
     1021 ttttgtggtt gttcgaacca gacacatcca catataccgt ctttaggttc gcgaattgag
     1081 taacggattc gcgatacttc gagtcgtgca tgtgtagtct gcaatgctag gtccattgct
     1141 gttcttaacc atggtgcagc ggcctgcctg atagctataa aatgctcgag tgacaggcgc
     1201 cgtcttttct tctcatcagt cctacgcatt ttttttctga tggccgggtt atccagcatt
     1261 agtgattcat cgaccgcata agagaacaac tttttaagga agctgacctt tctgttctgc
     1321 acatttgcgg atgcgcaggc atgatattta ttgatgtagg tattaacgtg ttcaagtgca
     1381 atatcgcatg ctggaacatt tacgaaaaac gcttttacgc gtagagcgtc atttttccag
     1441 tcatctaagg tgctctggga aggacgttcg tcttcgataa tccgggtcat tatgtgatca
     1501 acatgttcag caaatggttt tgcttctccg ataacaccgc cagattctct aataagatta
     1561 tctactgatg gagataattc tggtcgcatc ctcaggttgt actctctggc gattgcaatg
     1621 gctattgccc tatccttacc tatatttttc ttctttccgg taataagtgt gaatttataa
     1681 acacctcgat ctttatcaaa aatcagataa tcaggaagat gtctgtattc ttttttacgt
     1741 ggccttgccg ccatggtcac ccctcattta ttaacttgcg aacagcttga ctaaccattg
     1801 agtcgactcc ccatttttct gtttcgcaga caaaaacaga accgtccacg atgcgtccca
     1861 tgagtagacc gttctcgacc caacgtttta tcgttcggtt gtcaggaatt gagccattag
     1921 agaattcacg gcgtccccat tggctcgctt tcattagttt tgccatggct gtttctccac
     1981 ttagcccgct gcacacgggt agtaatatca aattccagtc ctgataatta attttgttct
     2041 ctggttgcta cttgttttat tggcctgatg ctgtccagga gcagacggcg gcgcatgttt
     2101 ggcgcgcccc aacggtaacc agtctttttg tcgtaggatt cacaacgtcc gacaacccag
     2161 gaggtttcag tggaatgtaa tttcatccgc ttttcaccgt ctcgggtgat aacaattcct
     2221 gtatgagttt ttatcacgct cattttttat tctccggtgc tttcggcatt actgcccagt
     2281 gggtaatatt gacgttttca aggtccccga cctgaaatgt ccactgccat tctccggttt
     2341 ctttttgccc ccaatgtgta ccagagagaa cgccagccaa tcagccagcc ttctccatta
     2401 gcatcaaata acagaacact ttcatgtctg ttttgtaaaa aggacggtac cagtcggaag
     2461 caagggtaca agctggtacc tccaagacta cacacagcat aaagttgtgg tgccgggtgc
     2521 ctcccggtgc ctggcgaagg ttgcacacca ggcgggtggg tatccacaga aggtcgactg
     2581 tcagcctcaa cctttacccg cgtgcgctga gccgcattca ccacaacgct aaggattctc
     2641 tctggttgaa aatacttagc tgttatgtgc ctgcttttag ccacatcagg cgaggtggac
     2701 ctagttattc cccaacaaca aggatttggt tattatgtaa ccctccccaa caacgataag
     2761 gatttatatg gaacgatgtg tagataagta tgaggagagg catgtgccgt taaggcaaaa
     2821 gcctccagtt cctccaaaac cacccaagga aaactgagac taatatgacc agagacgatt
     2881 ataaatttta tattcactac tcttatgtat tggagaagat gaattacacg ttgttaactc
     2941 gtattgataa attaataacg ttgatgttaa tcgttctcgg tttttcagtt ttcgccccgt
     3001 acagtaattt atttattttc ggtttgtttg ttgccgtact ttcggttctt cagttggtct
     3061 atcagttcgg ccaggaggct gggatgtcta aagaacaagc gaggcattac aaaagactgc
     3121 tgattgagtc tgatactctt tctgaagatc agttgcaagc taggtattta aaaatccaag
     3181 ataccgatag taatccatgg aaatcacttg aacgagcggc tttcattcgg gcctgcattt
     3241 ttgctggtgt tccaactaag tacgatctaa caaccaaaga aaaatttatt gcttggtgtg
     3301 cgggagatct acctctagag aatgaactaa cggatattaa tgatgaccaa caagcataat
     3361 ccagttcacg gacatgtacc tccgaagccg aaaccaccga aaccgaagaa atgagacata
     3421 ataggattgg ataatgagtc gaccaataga gccttttcat attccacctc gtcccaggcc
     3481 accagatcca ggcccaaagt gagggttact gatttttaaa gagcgaagcg tccggtaggg
     3541 cgcttttttg ttgctaacga atcatcttgg acttcatatg ccccaggcgg ctacttcgtg
     3601 agcgtcctgc ctgtttgttg tttctcttgg gtacattatg tatctcaaag gtacattgtc
     3661 aagcataaaa aaacctgccg aagcaggttc ataaacattg attaggcttt gattttgtat
     3721 cttcttggtt ttcctgagaa aatcacagta ccaattatag agcaattacc gttgatctta
     3781 atgtaaggct caggccagtt tgggtttaac gctttgagat aacgctgtgt cccatcttct
     3841 atcaaccttt tgaaggtggt ttcacctgta tcgtgcatca atgcaataac gtcgtcaccg
     3901 tggcaggcag gtacttcagg atcgacaaaa atcatgtctc ccgggcggta ctcatcaatc
     3961 attgaatcac ctatcacccg caagatataa gtcatttccc cacagggtac agggcaggga
     4021 tacgtttctg ctgtgctcaa atcaacctca gaatatccaa cttctttcca tgctccggcc
     4081 tgtacccatg atatgacagg gactaatgtg atttgtttat tagtgattga aacatcaggt
     4141 ttttttgtga tgttcgttgt ctggtgttct tgatcgagcc atccgacagg caggtcgaaa
     4201 catttttcga tgtgtcgtgc catgctgtca ccgatatttt tagtagcacc atctcccata
     4261 aacctgctgg tttgggttgg ctcgcgatca atcatagtgg caaaggaaga attcccgcca
     4321 acaccatctc tcagttttct ggcgttagac cgccggatgt catggattgt tttcataacg
     4381 aaattaaaac ccttgtaccg ttaaggtaca agtatcttga aggttcattt taatcatgta
     4441 atatgtatac cggaggtaca tattgtatga aagcgtattg ggactcttta accaaagaac
     4501 agcagggcga gttggccgga aaagttggct caacacctgg ctacttacgg ctggttttca
     4561 atggctataa aaaagccagt tttgtgctgg ctaaaaaact tgagcaatgc acgtcaggtg
     4621 caattacgaa atctgactta agaccggata tctatccgaa agattagcag aacactttca
     4681 atttttaacc acagaacgat gaggctaatc gtgggtaagc atcactggaa aatagaaaaa
     4741 cagcctgagt ggtacatgaa agctgtcaga aaaactatcg cggcgttgcc gggtggttac
     4801 gctgaagccg ctgactggct ggatgtaaca gagaacgcat tatttaaccg ccttcgtgcc
     4861 gatggcgatc agattttccc gctgggatgg gcaatgattt tgcaacgtgc tggtggaact
     4921 cacttcattg ctgatgctgt ggcgcagtct gcaaatggcg tctttgtgtc tcttcctgac
     4981 gtcgaggatg tggacaacgc cgatattaac cagcgtctgc tggaagtcat tgaacagatt
     5041 ggcagttatt caaaacagat tcgttcagca atcgaagacg gtgtagtgga accgcatgag
     5101 aagacagcaa ttaatgacga gctgtacctc tcaatttcga agctgcagga gcatgcagca
     5161 ctggtctaca aaattttttg catttcagaa agtaatgacg cccgcgagtg tgcagctccg
     5221 ggcgccgtgg cgtgtcgtga ctgtggagaa actaacgcat gaacagttta acaacacatt
     5281 accgtcgctc gcaactgatt gcacttcctg taccgggtgg aaaagcgaag gtggagtatt
     5341 gctatgcagt gaatgtacca ggtgacaggg aaattgtaac ccacagcttt gcagagtggg
     5401 ctgtgggcga tttcaaccgg caaaaggaga cagtcctttg cgacaagtta accgctggtt
     5461 caaagatcac tacggagtgc ccgtcagagt cattcgttgg gagccggaaa cacaacgggt
     5521 tatctacctc cgcgaaggct atgagcatga gtgcttcagc ccgctcgaac agtttcgtcg
     5581 taaattcagg gaaatagagg tcggtcatga gcactaaatt aaccggctat gtatgggatg
     5641 gttgcgctgc gtcaggcatg aagttatcca gcgtggcaat tatggcccgc ctggctgatt
     5701 tcagtaatga cgaaggtgtg tgctggccat caattgaaac cattgcccgc cagattggcg
     5761 cggggatgag caccgtcaga acggctatcg cacggctgga agcagaaggc tggttaactc
     5821 gtaaggcgcg tcgccagggt aaccgcaatg cgtcgaatgt ttatcagctt aacgttgcga
     5881 agcttcaggc agcggcattt tctcaactgt cagattctga cccgtcaaaa tctgacgcat
     5941 caaaatctga cccgtcaaaa tttgatgcgt cgaaatctgg caaaaaagcg ggttttcacc
     6001 cgtcagaatc tggcggggat ccgtcagtaa aatcaaaaca tgatccgtca gataaaaaaa
     6061 actctcgtcc ggacgcttcg caaccggaca cgcagatgga tgaacaggat tttttaactc
     6121 gccatcctga tgcggttgta ttcagcccta aaaagcgcca gtgggggacg caggatgatt
     6181 tgacctgcgc acagtggctc tggaaaaaaa tcatcgccct gtacgagcag gctgccgaat
     6241 gtgacggcga ggtggttcgt cccaaagaac cgaactggac agcctgggca aacgaaattc
     6301 gcctgatgtg tgtgcaggat ggtcgtactc acaaacaaat ctgcgagatg tacagccgcg
     6361 tcagccgcga tccgttctgg tgccgtaacg tgctcagccc gtcgaagctg cgggaaaaat
     6421 gggatgagct ttccctgcgc ttatcgccgt ccgtaagcac gtacaccgaa aaacgcgaag
     6481 acccgtactt caaatccagt tacgacaacg tggactacag ccagatcccg gcaggattca
     6541 gggggtgatc atgagtcttt tgaatgacgt tcagaaattc attgaagccc atccggggtg
     6601 tacttccgga gacattgcgg atgcttttgc tggttactca cggcagcgcg ttctgcagtc
     6661 agcaagcaag ttacgtcaga gtgggcgtgt ggctcaccgt tgtgaagggg atacacgcag
     6721 acatttcccg cgcctgactg agagagcgca ggaactggaa ccacaaccag ttcgagaaac
     6781 cagatctgtg cgcaatttct atgtcggcac taacgatccc cgggtgattt tgtgcctgac
     6841 ccgccaggct gaaaaactgg agtccagggg cttataccgt cgtgctgcaa cggtgtggat
     6901 ggcggcattc cgtgaaagcc actcccagcc agaacgaaac aattttctgg cgcgtcgtga
     6961 gcagtgttta cggaaaagca gcaagcgcgc tgtatcgagt gatgagtggt atctgtcagg
     7021 gaattacgtg ggggcgtaat gacgacgtta actcaatgcc agcagcaggt gctggatatg
     7081 ctgatttctt atcagaaaga gcgtggcttt ccgccaacca atcaggaggt ggcaaccatg
     7141 ctgggatacc gttcagtgaa tgcagcggta gagcatcttc gcgcactgga gaaaaaaggc
     7201 gtcatcacga taaagcgtgg cgtggcccgg gggataacgc ttcataccgc ggtgaaggac
     7261 gacgacagcg aggcggtcgg gattatccgc gcactgcttg ccggtgagga aaacgcaagg
     7321 ctgcgtgcaa cccactggtt acatgagagg ggcctgaaag tatgaagctg atcctgcctt
     7381 ttccgcccag cgtgaacacg tactggcgac accccaacaa aggggcgttt gctggtaaga
     7441 gcctgataag cgcggcgggg cgaaaattcc agagcgcggc gtgtgcagca atagttgagc
     7501 agttacgtcg tctgccgaaa ccaacgtcgg cacctgcttc agtggagatc gtgttgtttc
     7561 ctccggataa ccggatccgc gatctggaca actataacaa ggcgctgttt gacgccctga
     7621 cccacgcggg tgtgtgggaa gacgacagcc aggtgaaaag aatgttggtg gagtggggac
     7681 cggttatccc ggaagggaag gtcgagatca ctatcagtaa gtacgagaaa acggcgggtg
     7741 cagccgcctg atcaagagga gaaacgaagt atgaataatc tgatggtcat tgatggtatt
     7801 gaagttcgtc gtgatgctta tgggcgttac agcctgaacg atctgcacag ggctgccggt
     7861 tctctggata agcataagcc tgcattctgg ctccgcaatg agcaaactga acgtttaata
     7921 agcgagttgc agatttgcaa ctcggtcaat atagagccag ttaacgttat tcgcggcgga
     7981 aataatcagg ggacgtatgt ctgtaaggaa ctggtgtatg cctatgcaat gtggatcagc
     8041 ccgtcattcc atctgaaggt gatccgtact ttcgacatgg taaccagcgc accggaaaaa
     8101 ttatccggac aggctgctga caagatgcag gctggagtga ttctgctgga ctttatgcgt
     8161 cgggagttaa acctgtctaa ctcatctgtg cttggggcct gtcaaaaact ccaggaggct
     8221 gttggcttac cgaatctggc accgcgctat gccattgatg ctcctgctga tgcacacgat
     8281 ggctcaagtc gccccacgct gtcgctgagt gcactgctga agcagtatgg tatccgcctg
     8341 acggctaatc aggcatatca ccagatggtg aagctgggga tcgttgaaca acgcgaacga
     8401 tacagccgta ccgcgattaa caacatcaaa aaattctggt cgctgacagc gaaaggctgc
     8461 atgttcggca agaacatcac cagtcccgca aatccgcgcg agacgcagcc gcatttcttc
     8521 gaatcccgat tccctgagct gttaaagctg ctcgataccg ttcattgagg tgaccgtgag
     8581 agcactactg acccctgaaa ttgccccgcg tatggggatc gtattgttca gaccaggttc
     8641 agaactgatg cccctgttta tgcaggggcg tgtcctgctg gagcctgagc cggaacgtta
     8701 ttcatctttc gccagtggtg ccgttccggc agcatcacaa ccgctggcgg atgatcctgc
     8761 cgttcgggcc gtgttccgca atgaggcagt gatccgtcgt gctggtggcg tggaatgtct
     8821 tgaaagctgg ttacttcgtg aaaaaggctg tcagtggcct cactccgact ggcacagcga
     8881 aaacatgacc acaacgcgcc atgcgccggg cgcaatccgt ctgtgctggc actgcgataa
     8941 ccagttgcgt gaccagttca cggaacggct ggaatcaatg gcaacggata actgtgcccg
     9001 ctgggtgtta tctgttgtgc gccgtgatct cggttttgat gatagtcacg ttgtgacaat
     9061 gccggaactg tgctggtggc tggttcgtaa tgacctggcg gatgccttac cggaaagtgc
     9121 agcccgtaag gcactgagat taccgaagcc tgttgtgccg tctgtcaccc gggaaagtga
     9181 ccttgttcct tcggttcctg ccaccagcat catccaggat aaggcgaaaa aggtgctggc
     9241 gctgaaagtg gatccggagt caccggagtc ttttatgtta cgcccaaaac gtcgccgctg
     9301 ggttaatgaa aagtacacgc gctgggttaa gacacagccg tgtgcatgtt gtggaaagcc
     9361 cgctgatgat ccccaccacc tgataggcca tggtcagggt ggaatgggga caaaagcgca
     9421 tgacctcttt gtgttgcctt tgtgcagaaa gcatcacgac gagctgcatg cggataccgt
     9481 ggcatttgaa gagatgtatg gctcccagct ggagctgata tttcgtttta tcgatcgtgc
     9541 gctggcaatt ggtgtgctgg cctgattttg tggagaaagt tgatgcgtga tatgtatgaa
     9601 gtaatggatc gttggggagc ttgggctgct tcagacaata gcggagtgga ctggcaaccg
     9661 gtagccgctg gcttcaaggg acttttacct catggcaaaa agtcccggat tcagtgtgat
     9721 gatgacgaag gcattatgat agacagttgt gtggctcggt tgcgtaaata taggcctgaa
     9781 gaatatgagc taatcattgc tcactttgtt atcggtatct cattacgcac tattgcgaag
     9841 aagagaaaat gctctgatgg gactataaga aaaaagttgc aagctgcatt ggga
//
LOCUS       DAPGUL010000151         9831 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.154, whole genome shotgun sequence.
ACCESSION   DAPGUL010000151 DAPGUL010000000
VERSION     DAPGUL010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9831)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9831)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9831
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.154"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(1..802)
                     /locus_tag="RHX21_004131"
                     /pseudo
     CDS             complement(1..802)
                     /locus_tag="RHX21_004131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611435.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(880..1131)
                     /locus_tag="RHX21_004132"
                     /pseudo
     CDS             complement(880..1131)
                     /locus_tag="RHX21_004132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611998.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1250..2329)
                     /locus_tag="RHX21_004133"
     CDS             complement(1250..2329)
                     /locus_tag="RHX21_004133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HDV1989245.1"
                     /translation="MFGYYREVFVKDIRHILSVAVCLYSSLATGGSAIYFNFKGVQTG
                     EAINNTTSGQTITVPVALNSLGNTGTVAGVPECNGQYDINYYTVFYHRLGIPKKIQLG
                     NQWVDVQVNAPGYVRDTEDQNYVYYYSNEENGGRGYRYAGKSCWGAGEVVDVTPFAPG
                     IPPAVTLSVRLPPGLPDGLTEMLIPVKYGKNVNFLRGIWDWNTHRKDLMSAGTTIAAQ
                     STATSFLLYRRDIINKAKCSFDKPSYDIDHKNVSINDALANIAMAETNVKLTCTAPTD
                     VKIKLSTPKTPNYNNSHFSVNLGNGWDSVISLDGYSYDEANLQNKYVTQSGRTIKIGS
                     KLYGDVSKVKPGGINGSLVMTFDFQ"
     gene            complement(2405..2905)
                     /locus_tag="RHX21_004134"
     CDS             complement(2405..2905)
                     /locus_tag="RHX21_004134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042092232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV1989246.1"
                     /translation="MIRLSLFISLLLTSVAVLADVQINIRGNIYIPPCTINNGQNIVV
                     DFSNVDPGKVSADPQNTSQGKVAKTISISCPYNSGNPWIKVTGRVDNNSLMTDMTNLR
                     IALYQGNNTSTRLTLGEGSGSGYRVTAGLDTTTSTFTFMSVLFRNGDLNGGAFSATAS
                     MSMIYN"
     gene            complement(2981..3508)
                     /locus_tag="RHX21_004135"
     CDS             complement(2981..3508)
                     /locus_tag="RHX21_004135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV1989247.1"
                     /translation="MKKIIGLCLPVMLGAVLMSQHAHAADNLTFKGKLIIPACTVTKA
                     EVDWGNIEIQTLSQNGNHEKEFTVNMQCPYNLGTMKVTITATNTQNNNSILVPNTSTT
                     TGNGLLIYLYNRNQNGSIGSPIVFNSPFTPGYITGQVPARNISLYAKLGYKGNIQNLR
                     AGTFSATATLVASYS"
     gene            complement(3535..4071)
                     /locus_tag="RHX21_004136"
     CDS             complement(3535..4071)
                     /locus_tag="RHX21_004136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001558207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HDV1989248.1"
                     /translation="MIKSTGALLLFAALSAGQAMASDVAFRGNLLDRPCHVSGDSLKK
                     HVVFKTRASRDFWYPPGRSPTESFVIRLENCHATAVGKIVTLTFKGTEEAALPGHLKV
                     TGVNSGRLGIALLDTDGSSLLKPGTFHNKGQGEKVTGNSLELPFGAYVVATPEALRTK
                     SVVPGDYEATATFELTYR"
     gene            complement(4081..4662)
                     /locus_tag="RHX21_004137"
     CDS             complement(4081..4662)
                     /locus_tag="RHX21_004137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein papJ"
                     /protein_id="HDV1989249.1"
                     /translation="MVVNKTTAVLYLIALSLSGFIHTFLRAEERGIYDDVFTADELHH
                     YRINERGGRTGSLAVSGALLSSPCTLVSNEVPLSLRPENHSASAGAPLMLRLAGCGDG
                     GALQPGKRGVAMTVSGSLVTGPGSGSALLPDRKLSGCDHLVIHDGDTFLLCRPDRRQE
                     EMLAAWRKRATQEGEYSDARSNPAMLRLSIKYE"
     gene            complement(4699..5433)
                     /locus_tag="RHX21_004138"
     CDS             complement(4699..5433)
                     /locus_tag="RHX21_004138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HDV1989250.1"
                     /translation="MWKLSMIRKKILMAAIPLFVISGADAAVSLDRTRAVFDGSEKSM
                     TLDISNDNKQLPYLAQAWIENENQEKIITGPVIATPPVQRLEPGAKSMVRLSTTPDIS
                     KLPQDRESLFYFNLREIPPRSEKANVLQIALQTKIKLFYRPAAIKTRPNEVWQDQLIL
                     NKVSGGYRIENPTPYYVTVIGLGGSEKQAEEGEFETVMLSPRSEQTVKSANYNTPYLS
                     YINDYGGRPVLSFICNGSRCSVKKEK"
     gene            complement(5504..8014)
                     /gene="papC"
                     /locus_tag="RHX21_004139"
     CDS             complement(5504..8014)
                     /gene="papC"
                     /locus_tag="RHX21_004139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_151035092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P fimbrial usher protein PapC"
                     /protein_id="HDV1989251.1"
                     /translation="MKDRIPFAVNNITCVILLSLFCNAASAVEFNTDVLDAADKKNID
                     FTRFSEAGYVLPGQYLLDVIVNGQSISPASLQISFVEPQSSGDKAEKKLPQACLTSDM
                     VRLMGLTAESLDKVVYWHDGQCADFHGLPGVDIRPDTGAGVLRINMPQAWLEYSDATW
                     LPPSRWDDGIPGLMLDYNLNGTVSRNYQGGDSHQFSYNGTVGGNLGPWRLRADYQGSQ
                     EQSRYNGEKTTNRNFTWSRFYLFRAIPRWRANLTLGENNINSDIFRSWSYTGASLESD
                     DRMLPPRLRGYAPQITGIAETNARVVVSQQGRVLYDSMVPAGPFSIQDLDSSVRGRLD
                     VEVIEQNGRKKTFQVDTASVPYLTRPGQVRYKLVSGRSRGYGHETEGPVFATGEASWG
                     LSNQWSLYGGAVLAGDYNALAAGAGWDLGVPGTLSADITQSVARIEGERTFQGKSWRL
                     SYSKRFDNADADITFAGYRFSERNYMTMEQYLNARYRNDYSSREKEMYTVTLNKNVAD
                     WNTSFNLQYSRQTYWDIRKTDYYTVSVNRYFNVFGLQGVAVGLSASRSKYLGRDNDSA
                     YLRISVPLGTGTASYSGSMSNDRYVNMAGYTDTFNDGLDSYSLNAGLNSGGGLTSQRQ
                     INAYYSHRSPLANLSANIASLQKGYTSFGVSASGGATITGKGAALHAGGMSGGTRLLV
                     DTDGVGGVPVDGGQVVTNRWGTGVVTDISSYYRNITSVDLKRLPDDVEATRSVVESAL
                     TEGAIGYRKFSVLKGKRLFAILRLADGSQPPFGASVTSEKGRELGMVADEGLAWLSGV
                     TPGETLSVNWDEKIQCQVNVPETAISDQQLLLPCTPQK"
     gene            complement(8073..8660)
                     /gene="papH"
                     /locus_tag="RHX21_004140"
     CDS             complement(8073..8660)
                     /gene="papH"
                     /locus_tag="RHX21_004140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001366863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P fimbrial minor subunit PapH"
                     /protein_id="HDV1989252.1"
                     /translation="MKNFCVLFVMYFWSTLLHAVSSEPFPPPGMSLPEYWGEEHVWWD
                     GRAAFHGEVVRPACTLAMEDAWQIIDMGETPVRDLQNGFSGPERKFSLRLRNCEFNSQ
                     GGNLFSDSRIRVTFDGVRGETPDKFNLSGQAKGINLQIADARGNIARAGKVMPAIPLT
                     GNEEALDYTLRIVRNGKKLEAGNYFAVLGFRVDYE"
     gene            complement(8723..9274)
                     /gene="papA"
                     /locus_tag="RHX21_004141"
     CDS             complement(8723..9274)
                     /gene="papA"
                     /locus_tag="RHX21_004141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001460230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P fimbria major subunit PapA"
                     /protein_id="HDV1989253.1"
                     /translation="MIKSVIAGAVAMAVVSFGVNAAPTTPQGQGRVTFNGTVVDAPCS
                     ISQKSADQSIDFGQLSKSFLANDGQSKPMNLDIELVNCDITAFKNGNAKTGSVKLAFT
                     GPTVSGHPSELATNGGTGTAIMIQAAGKNVPFDGTEGDANLLKDGDNVLHYTAVVKKS
                     SDGNAQITEGAFSAVATFNLSYQ"
     gene            complement(9480..9794)
                     /locus_tag="RHX21_004142"
     CDS             complement(9480..9794)
                     /locus_tag="RHX21_004142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin biosynthesis transcription regulatory
                     family protein"
                     /protein_id="HDV1989254.1"
                     /translation="MAHHEVISRSGNEFLLNIRENVLLPGSMSEMHFFLLIGISSIHS
                     DRVILAMKDYLVGGHSRKEVCEKYQMNNGYFSTTLGRLIRLNALAARLAPYYTDESSA
                     FD"
BASE COUNT         2534 a         2592 c         2047 g         2658 t
ORIGIN      
        1 cgcagttttt ctccgttatc acagcggaac tcgaacccgt cagagcacca tcgctgatta
       61 ctttctttca cagccactct gccggtatgt gcccgtttcg atggcggtac agcgggtttt
      121 cgctcaagca acagcgcatt ctggcgcatg atccggtaaa tacgtttggc attgatcgca
      181 ggcataccat caagttcggc ctgtctgcga agcagcgccc atacccgacg ataaccatat
      241 gtgggcagct ctccgataac atggtgtata cggagaagca catccgtatc atctgagtga
      301 cggctgcggc gaccatcttt ccagtcatcg gttcgtctga gaatgacgtg caactgcgca
      361 cgcgacaccc ggagacaacg gctgactaag cttactctcc atccccgggc aataagggcg
      421 cgtgcgctat ccactttttt gcacgcccat attcaacggc ttctttaagg agttcatttt
      481 ccatcgtttt tttgccgagc aggcgctgga gttctttaat ctgcttcatg gcagcagcaa
      541 gttcagaggc aggaacgacc tgttctcctg cggccacagc agtaagactt ccctcctggt
      601 attgcttgcg ccagagaaat aactggctgg ctgccacacc gtgttgccgg gcaacagggg
      661 agaccgtcat tcccggttca aaactctgct gaacaatagc gatcttttcc tgtgtagtac
      721 gccgtctgcg tttctccggt cctaagacat caatcatctg ctctccaatg actagtctaa
      781 aaactagtat taagactatc acttaaataa gtgatattgg ttgtctggag attcaggggg
      841 ccagtctagg gtgttgcatt gacagattga atctacagtt aatatatctc gctcaaggcg
      901 agcttcattt aacgccttac gcagttgcag aatttcagat tccagttcag ccaccgtgcg
      961 ggaaccagga gtaccgagcc cttttctggc ggcggtaacc cattgtccta aagtgccttc
     1021 aggaagagat aatcgggaag cgccttcact gatcgaaagt tgattttcaa gaaccgttct
     1081 gacagcttcg gctttgaact ctttagagta acgttgggtt tttctgctca ttattagctc
     1141 cttctgatgc cattctattt caggaaggag tgtccgttaa actcaggcta cctcaatatg
     1201 aatacgcatc cggatactta ccagctcagg agtccccaac aaattcagat tactgaaagt
     1261 caaaagtcat aaccagacta ccattaatac ccccgggctt cacttttgaa acatctccgt
     1321 aaagcttgct tcctattttg attgttcttc ctgactgggt aacatactta ttttggagat
     1381 tcgcttcatc ataagaataa ccatcaagac tgattacaga atcccagcca ttcccaagat
     1441 taactgaaaa atggctatta ttataattag gtgtttttgg tgttgataat ttaattttta
     1501 catctgtagg tgcggtacat gttaacttaa cattagtttc agccatggct atatttgcta
     1561 atgcatcgtt gatactaacg tttttgtgat ctatatcgta tgatggctta tcaaatgagc
     1621 attttgcctt atttatgata tcccttctat acagaaggaa ggatgttgct gttgactgag
     1681 ctgcaattgt tgtccctgcc gacatcaaat ccttccgatg agtattccag tcccatatgc
     1741 ctcttaaaaa attgacattt ttcccatatt tgaccggtat cagcatctca gtcaaaccat
     1801 cgggtaagcc cggcggaagg cgtacactca gagttacagc aggggggata cccggggcaa
     1861 acggagttac gtctacgacc tcccctgccc cccagcaact ctttcctgca tatctgtaac
     1921 cacgaccacc attttcctca ttggagtaat aatacacgta attttgatct tctgtatccc
     1981 tgacataacc aggtgcattt acctgtacat cgacccattg attccctaat tgaatttttt
     2041 ttggtatacc taacctgtgg tagaaaaccg tataataatt tatatcatat tgtccattac
     2101 attcagggac acctgctaca gttcctgtat tgcctaaaga gttcaacgcc acaggtactg
     2161 tgattgtttg cccggaagtc gtattattaa tggcctctcc tgtttgaact cctttaaagt
     2221 taaaataaat tgcactccct cccgtagcca aactgctgta aagacacaca gcgacagata
     2281 aaatatgtct aatatccttc acaaacacct ctctgtaata tccgaacatc tgatagactc
     2341 agtatatttt cgctatttgg catgaaccca tgataatcat aattcattct ctgataataa
     2401 ggacctagtt atatatcata ctcatgctgg ctgtagcact aaatgcaccg ccattcagat
     2461 ctccgtttct gaacagcacc gacatgaaag taaatgttga tgttgttgtg tccagaccag
     2521 cggttactct gtaaccgctt cctgagcctt cacctaatgt gagtctggtt gacgtgttat
     2581 tcccctgata taaggcaatt ctcagatttg tcatatcggt cataagtgaa ttgttatcca
     2641 ctcttccggt caccttgatc cacggatttc cactgttata tggacaggat atgcttatcg
     2701 tttttgccac cttcccctga gatgtattct gtgggtcagc actcaccttg cccgggtcga
     2761 cattactgaa gtcaacaacg atattctgtc cgttattaat ggtgcatgga ggaatataga
     2821 tatttcctct gatgttaatc tgcacatcag ccagtacagc gaccgatgtc agaagcaacg
     2881 atataaataa tgataaacga atcattcccc ctccggagag cggcacagaa aacattttat
     2941 tttatgagat ataaaattcg atgtatttta actgatagca ttacgaatat gatgcaacca
     3001 gcgttgctgt tgcagaaaat gttcccgccc gcaaattctg tatatttcct ttatatccaa
     3061 gttttgcata gagagaaata tttctggccg gaacctgacc tgtaatatag ccaggggtaa
     3121 atggcgaatt aaaaactata ggtgaaccaa tagaaccatt ttgatttctg ttgtaaagat
     3181 agataagcaa tccattacct gtcgtagttg atgtattagg caccagtata gaattgttat
     3241 tctgagtatt cgtggctgtt atcgtaacct tcattgttcc cagattataa ggacactgca
     3301 tattcacagt aaactctttt tcgtgatttc cattttgact cagggtctga atctctatat
     3361 ttccccagtc aacctctgcc tttgttacag tacaggcagg aataatcagt tttcctttaa
     3421 aggtcagatt atcagctgca tgtgcatgct gagacattaa cactgccccc agcattaccg
     3481 gaagacacaa acctattatc tttttcatct gaaatctcct gtacaaaatt ttttctaacg
     3541 atatgttaat tcaaacgtgg ctgttgcttc ataatcaccg ggtaccacac tcttcgtccg
     3601 cagggcttcc ggcgttgcca caacatacgc gccgaaagga agctcaagac tgtttccggt
     3661 aaccttttcc ccctggcctt tgttatggaa ggtgccgggt ttcagcagac tgctgccatc
     3721 ggtgtccagc agtgcaatgc ctaaccggcc ggaattcact ccggttacct tcagatggcc
     3781 cgggagggcc gcctcttccg tccccttaaa ggtcagggtc acaattttgc caactgctgt
     3841 tgcatggcag ttttccagcc tgatgacaaa cgactctgtc ggcgaacgtc cgggcggata
     3901 ccagaaatcc ctggacgcgc gggttttgaa gacgacatgt ttcttcagac tgtcaccgga
     3961 cacatggcag ggtctgtcaa gcagattacc cctgaatgcc acatctgagg ccattgcctg
     4021 cccggcagac agtgcggcaa acagtaaaag agcgcctgtg ctttttatca tcacatcccc
     4081 ttactcatat tttatgctca gacgcagcat ggccggattg ctcctggcat cagaatactc
     4141 accctcctgt gtcgcccttt tcctccaggc ggccagcatc tcctcctgcc gccggtcagg
     4201 ccggcacagt aaaaaggtat caccatcgtg tataacaaga tggtcacagc cggatagctt
     4261 acggtcagga agtaaagcac ttccgcttcc gggaccggtt accagtgagc cggagactgt
     4321 catcgcaact ccccgttttc cgggctgaag tgcaccaccg tccccacatc ctgccagcct
     4381 cagcatcaga ggtgctccgg ctgacgcaga gtgattctcc ggccggaggc ttaacggcac
     4441 ctcattactc accagcgtgc agggtgagga cagcagtgca ccactgactg ccaggcttcc
     4501 ggtgcgtccc ccccgttcat ttatccggta atgatgcaac tcatctgcag taaagacgtc
     4561 atcgtatata ccccgctctt cagcccgcag gaaagtatgg atgaaaccac tcagcgacag
     4621 tgcaataaga tacagtactg ctgttgtttt attcacaacc ataatatccc acccgcattt
     4681 aaccgttatt gcggtacatt atttctcttt tttcacagag caacggctgc cattacagat
     4741 aaacgacagt accgggcgac caccatagtc gttaatataa gacagataag gggtattata
     4801 atttgccgat tttactgtct gctctgaacg gggagacagc atcacggttt caaactcacc
     4861 ttcctctgcc tgtttttcac ttcctcccag accaataaca gtgacataat agggcgttgg
     4921 gttttcaata cgatacccac cgctgacttt gttcagaatt aactggtcct gccatacttc
     4981 attcggtctg gttttaattg ctgccgggcg ataaaaaagc tttattttgg tctgtaaggc
     5041 tatctgcagt acattggcct tttcactcct cggcggtatt tcccggagat taaaataaaa
     5101 cagtgattcc ctgtcctgag gaagtttact gatatccggt gtggtactca gcctgaccat
     5161 gcttttcgca cccggctcaa ggcgctgaac cggaggggtg gcaataaccg gccctgtaat
     5221 aattttttcc tgattttcat tttctatcca tgcctgagca agatagggca gttgtttgtt
     5281 atcattggag atatcaagcg tcattgactt ctcactcccg tcaaacaccg cgcgggttct
     5341 gtccagcgaa acagcagcgt cagccccgga tataacaaac agggggatgg cagccatcag
     5401 aatctttttt cgaatcatac ttaatttcca cattctgtaa tttcacctgg tccggaaaat
     5461 ggcataaccg cattcatcag ccgttaatat tccggacttt catttatttc tgaggcgtac
     5521 agggaagcaa taactgctgg tcagatattg ctgtctccgg tacatttacc tgacactgta
     5581 ttttttcatc ccagtttacc gacagggttt cccccggcgt cacgccactc agccaggcaa
     5641 ggccttcatc ggccaccatg cccagttccc ggcctttttc actggttaca ctggcaccaa
     5701 acgggggctg agagccatca gcaagacgca gtattgcaaa cagacgtttc cctttaagca
     5761 cgctgaattt ccggtaacca atggcacctt ctgtcagcgc cgattccaca acagaacggg
     5821 ttgcttccac atcatccggt aagcgcttca ggtcaacaga agttatattc cggtaataac
     5881 tgctgatgtc agtcaccacg cccgttcccc agcgatttgt caccacctgc ccgccatcaa
     5941 ccggtacacc tcccacacca tccgtgtcaa caagaagacg tgttccaccg gacattcccc
     6001 ctgcatgtaa cgccgcacct tttccggtaa ttgttgcccc accggaagca ctgacgccga
     6061 aagacgtata tcctttctgc agggatgcaa tattcgcgga caaatttgcc agcggactac
     6121 gatgactgta ataggcatta atctgacgtt gcgatgtcag tccaccgcca ctgttaaggc
     6181 cggcgttcag gctgtagctg tccagaccgt cattgaacgt gtcagtgtag ccggccatat
     6241 tcacataacg gtcattactc atactgccac tgtagctcgc tgtccccgtc cccagcggca
     6301 cggatatacg caggtaagca gaatcgttat cacgccccag atatttagac cttgaggctg
     6361 acaatccaac cgccacaccc tgcagtccga aaacattaaa gtagcggttg acgctcaccg
     6421 tataatagtc cgttttccgt atgtcccagt atgtctgacg gctgtactgc aggttaaaag
     6481 aggtgttcca gtccgccacg tttttattca gcgtaacggt atacatctct ttttcccgac
     6541 tgctgtaatc attacggtag cgggcgttca ggtactgctc catggtcata tagtttcgct
     6601 ctgagaaacg atacccggcg aacgtaatgt cggcatccgc attatcaaac cgtttggagt
     6661 agctcagacg ccaggatttt ccctgaaacg ttctctctcc ctcaatacgg gctactgact
     6721 gcgtgatatc agcggaaagg gtccccggca cacccaggtc ccagccggca ccggctgcca
     6781 gtgcattata atcaccggca agcacagccc cgccatacag cgaccactgg ttactgagcc
     6841 cccaggatgc ctctccggtc gcaaatacag gcccttcggt ctcatgcccg tatccacggg
     6901 aacgaccgga gacaagtttg taccggacct gtcccggacg cgtcagataa ggaaccgagg
     6961 ctgtatcgac ctgaaaggtt ttcttccgtc cgttctgttc aataacctca acatcaagac
     7021 gtccgcgaac tgaactgtcc aggtcctgaa tactgaatgg ccctgcgggg accatagagt
     7081 cgtacagcac ccgtccctgc tgcgacacca caacacgggc attagtctcc gcaatcccgg
     7141 taatctgcgg tgcatagcct cgcagtctgg gcggcagcat ccggtcatcg ctttccaggc
     7201 tggctcccgt ataactccat gaccggaata tatctgagtt gatattattc tcgcccagcg
     7261 tcaggtttgc ccgccaccgg ggaatggcac ggaacagata aaagcgactc catgtgaaat
     7321 ttctgtttgt cgttttttcc ccgttgtagc ggctctgctc ctggcttccc tgatagtcag
     7381 cccgcaggcg ccagggcccc agattccccc ccacagtccc gttataactg aactgatgag
     7441 agtctcctcc ctgataatta cgggaaaccg tcccgttgag gttataatcc agcatcagtc
     7501 cgggaatgcc gtcgtcccag cgtgagggag gcagccaggt ggcatcagaa tactcaagcc
     7561 aggcctgcgg catattgatg cgtaatacgc ccgctccggt atcaggacga atatccactc
     7621 ccggcaaccc atgaaaatcc gcacactgac catcatgcca gtaaacaact ttatccagag
     7681 attctgctgt taaccccatc agtctgacca tatctgatgt cagacaggcc tgtggcaatt
     7741 ttttttctgc cttatctcct gacgactgag gttcaacaaa tgaaatctgt aacgatgcgg
     7801 gagaaatact ttgcccgtta acaatcacat ccagaagata ttgccccggc agaacataac
     7861 cggcttctga aaaacgggtg aagtcaatat ttttcttgtc cgctgcgtca agtacatctg
     7921 tattaaactc aacggcactg gctgcgttac aaaacagaga caacaatatc acacaggtaa
     7981 tattgttgac tgcaaaaggt attctgtctt tcattccacg catcaccaga ttcacaaaaa
     8041 agataaataa ccggacatct caccggagtg actcactcat aatcgacccg gaatcccagc
     8101 acagcaaaat aatttccggc ttcaagtttt tttccgtttc tcacaattct gagggtgtaa
     8161 tccagcgctt cttcattacc cgtcaatggt attgcaggca ttactttccc tgcccgggca
     8221 atattccccc tggcatcagc tatctgcaga ttaattcctt ttgcctgacc ggataaatta
     8281 aacttatccg gcgtttcacc ccggacgcca tcgaaagtca cccttatccg ggaatcagag
     8341 aaaaggttcc caccctgact gttaaattca cagtttctga gccggaggct gaattttctt
     8401 tcaggtccgg aaaaaccatt ctgtaaatcc cgaaccgggg tttcccccat atcaataatc
     8461 tgccaggcgt cttccatcgc cagagtacag gcaggtctga caacctcacc atgaaaagca
     8521 gccctgccgt cccaccatac gtgttcttct ccccagtatt caggaaggga catgccgggc
     8581 ggaggaaatg gctctgaaga tacagcatga agtaatgtac tccagaaata catcacaaac
     8641 agaacacaaa aattcttcat accttaaatg tcgttgtcag acacagggtg ggtcttgcct
     8701 caccctgtaa aaatcagatg aattactggt aacttaaatt aaaggttgcg actgcagaaa
     8761 aagcaccttc agtaatttga gcattaccat cagatgattt cttaacaaca gctgtataat
     8821 gcagtacatt atcaccatct ttcaggagat tagcgtcacc ctccgtacca tcgaagggaa
     8881 cgtttttacc cgcagcctga atcataatag ctgtgcccgt accgccgtta gtagctaact
     8941 cactaggatg accactaact gttgggcctg taaaagctaa cttaacgctc ccagttttag
     9001 cattaccatt tttaaaggca gtaatgtcac aattaactaa ttcaatatcc aagttcattg
     9061 gcttggattg accatcattt gcaagaaaac tttttgaaag ttgtccaaaa tcaatagact
     9121 gatcagctga tttctgagaa atgctgcatg gagcatcaac aacagttccg ttaaaggtta
     9181 ctctaccctg cccctgtgga gtagttggag cagcatttac accaaaagac accactgcca
     9241 tagctaccgc accggcaata accgacttaa tcataaataa caacctcttt ttcattactg
     9301 aacacaccag agatatctgg caatttaaaa tgacccgatt acctttaata atcagatcaa
     9361 tacaaataat attctcgtat tttcagggca ggttatttat cgacaaaata ctgatataac
     9421 ctgtctgctt tctgataagg acttcttttg atctgtaaga aactccggaa tgccatcatt
     9481 cagtcaaatg ccgacgactc atctgtataa taaggtgcaa gccttgctgc aagagcattc
     9541 agccgtataa gtctcccaag tgttgtactg aaatacccat tattcatctg gtatttctcg
     9601 cagacctcct tacgggagtg cccacctacc agatagtcct tcatagccag aatgaccctg
     9661 tcactgtgaa tagacgaaat acctatcagt aaaaaaaaat gcatttcaga catagagccg
     9721 ggcaacagta cgttctcgcg tatattcagc aaaaactcat ttcctgaccg actgatgact
     9781 tcatgatgcg ccatgtttcc cccttctgtc gggcccctgg atatatgctt c
//
LOCUS       DAPGUL010000152         9747 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.155, whole genome shotgun sequence.
ACCESSION   DAPGUL010000152 DAPGUL010000000
VERSION     DAPGUL010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9747
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.155"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            1..377
                     /locus_tag="RHX21_004143"
                     /pseudo
     CDS             1..377
                     /locus_tag="RHX21_004143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611482.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
     gene            460..717
                     /locus_tag="RHX21_004144"
     CDS             460..717
                     /locus_tag="RHX21_004144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000177060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989255.1"
                     /translation="MTLVNDTGFDPVFSGSIAESWRQQPCTPSYCCDWEAATMLRAFP
                     LAKKGEGRARLPSLYASFGKLGETPTHEDIIDNNRSINWPV"
     gene            complement(1274..2041)
                     /gene="fecE"
                     /locus_tag="RHX21_004145"
     CDS             complement(1274..2041)
                     /gene="fecE"
                     /locus_tag="RHX21_004145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter ATP-binding
                     protein FecE"
                     /protein_id="HDV1989256.1"
                     /translation="MTLRTENLTVSYGTDKVLNDVSLSLPTGKITALIGPNGCGKSTL
                     LNCFSRLLMPQSGTVFLGDNPINMLSSRQLARRLSLLPQHHLTPEGITVQELVSYGRN
                     PWLSLWGRLSAEDNARVNVAMNQTRINHLAVRRLTELSGGQRQRAFLAMVLAQNTPVV
                     LLDEPTTYLDINHQVDLMRLMGELRTQGKTVVAVLHDLNQASRYCDQLVVMANGHVMA
                     QGTPEEVMTPGLLRTVFSVEAEIHPEPVSGRPMCLMR"
     gene            complement(2042..2998)
                     /gene="fecD"
                     /locus_tag="RHX21_004146"
     CDS             complement(2042..2998)
                     /gene="fecD"
                     /locus_tag="RHX21_004146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter permease
                     subunit FecD"
                     /protein_id="HDV1989257.1"
                     /translation="MKIALVIFITLALAGCALLSLHMGVIPVPWRALLTDWQAGREHY
                     YVLMEYRLPRLLLALFVGAALAVAGVLIQGIVRNPLASPDILGVNHAASLASVGALLL
                     MPSLPVMVLPLLAFAGGMAGLILLKMLAKTHQPMKLALTGVALSACWASLTDYLMLSR
                     PQDVNNALLWLTGSLWGRDWSFVKIAIPLMILFLPLSLSFCRDLDLLALGDARATTLG
                     VSVPHTRFWALLLAVAMTSTGVAACGPISFIGLVVPHMMRSITGGRHRRLLPVSALTG
                     ALLLVVADLLARIIHPPLELPVGVLTAIIGAPWFVWLLVRMR"
     gene            complement(2995..3993)
                     /gene="fecC"
                     /locus_tag="RHX21_004147"
     CDS             complement(2995..3993)
                     /gene="fecC"
                     /locus_tag="RHX21_004147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dicitrate ABC transporter permease FecC"
                     /protein_id="HDV1989258.1"
                     /translation="MTAIKHPVLLWGLPVAALIIIFWLSLFCYSAIPVSGADATRALL
                     PGHTPTLPEALVQNLRLPRSLVAVLIGASLALAGTLLQTLTHNPMASPSLLGINSGAA
                     LAMALTSALSPTPIAGYSLSFIAACGGGVSWLLVMTAGGGFRHTHDRNKLILAGIALS
                     AFCMGLTRITLLLAEDHAYGIFYWLAGGVSHARWQDVWQLLPVVVTAVPVVLLLANQL
                     NLLNLSDSTAHTLGVNLTRLRLVINMLVLLLVGACVSVAGPVAFIGLLVPHLARFWAG
                     FDQRNVLPVSMLLGATLMLLADVLARALAFPGDLPAGAVLALIGSPCFVWLVRRRG"
     gene            complement(3990..4892)
                     /gene="fecB"
                     /locus_tag="RHX21_004148"
     CDS             complement(3990..4892)
                     /gene="fecB"
                     /locus_tag="RHX21_004148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418710.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate ABC transporter
                     substrate-binding protein FecB"
                     /protein_id="HDV1989259.1"
                     /translation="MLAFIRFLFAGLLLVISHAFAAMVQDEHGTFTLEKTPQRIVVLE
                     LSFADALAAVDVSPIGIADDNDAKRILPEVRAHLKPWQSVGTRAQPSLEAIAALKPDL
                     IIADSSRHAGVYIALQQIAPVLLLKSRNETYAENLQSAAIIGEMVGKKREMQARLEQH
                     KERMAQWASQLPKGTRVAFGTSREQQFNLHTQETWTGSVLASLGLNVPAAMAGASMPS
                     IGLEQLLAVNPAWLLVAHYREESIVKRWQQDPLWQMLTAAQKQQVASVDSNTWARMRG
                     IFAAERIAADTVKIFHHQPLTVVK"
     gene            complement(4937..7261)
                     /gene="fecA"
                     /locus_tag="RHX21_004149"
     CDS             complement(4937..7261)
                     /gene="fecA"
                     /locus_tag="RHX21_004149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+) dicitrate transport protein FecA"
                     /protein_id="HDV1989260.1"
                     /translation="MTPLRVFRKTTPLVNTIRLSLLPLAGLSFSAFAAQVNIAPGSLD
                     KALNQYAAHSGFTLSVDASLTRGKQSNGLHGDYDVESGLQQLLDGSGLQVKPLGNNSW
                     TLEPAPAPKEDALTVVGDWLGDARENDVFEHAGARDVIRREDFAKTGATTMREVLNRI
                     PGVSAPENNGTGSHDLAMNFGIRGLNPRLASRSTVLMDGIPVPFAPYGQPQLSLAPVS
                     LGNMDAIDVVRGGGAVRYGPQSVGGVVNFVTRAIPQDFGIEAGVEGQLSPTSSQNNPK
                     ETHNLMVGGTADNGFGTALLYSGTRGSDWREHSATRIDDLMLKSKYAPDEVHTFNSLL
                     QYYDGEADMPGGLSRADYDADRWQSTRPYDRFWGRRKLASLGYQFQPDSQHKFNIQGF
                     YTQTLRSGYLEQGKRITLSPRNYWVRGIEPRYSQIFMIGPSAHEVGVGYRYLNESTHE
                     MRYYTATSSGQLPSGSSPYDRDTRSGTEAHAWYLDDKIDIGNWTITPGMRFEHIESYQ
                     NNAITGTHEEVSYNAPLPALNVLYHLTDSWNLYANTEGSFGTVQYSQIGKAVQSGNVE
                     PEKARTWELGTRYDDGALTAEMGLFLINFNNQYDSNQTNDTVTARGKTRHTGLETQAR
                     YDLGTLTPTLDNVSIYASYAYVNAEIREKGDTYGNLVPFSPKHKGTLGVDYKPGNWTF
                     NLNSDFQSSQFADNANTVKESADGSTGRIPGFMLWGARVAYDFGPQMADLNLAFGVKN
                     IFDQDYFIRSYDDNNKGIYAGQPRTLYMQGSLKF"
     gene            complement(7348..8301)
                     /gene="fecR"
                     /locus_tag="RHX21_004150"
     CDS             complement(7348..8301)
                     /gene="fecR"
                     /locus_tag="RHX21_004150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fec operon regulator FecR"
                     /protein_id="HDV1989261.1"
                     /translation="MNPLLTDSRRQALRSASHWYAVLSGERVSPQQEARWQQWYEQDQ
                     DNQWAWQQVENLRNQLGGVPGDVASRALHDTRLTRRHVMKGLLLLLGAGGGWQLWQSE
                     TGEGLRADYRTAKGTVSRQQLEDGSLLTLNTQSAADVRFDAHQRTVRLWYGEIAITTA
                     KDALQRPFRVLTRQGQLTALGTEFTVRQQDNFTQLDVQQHAVEVLLASAPAQKRIVNA
                     GESLQFSASEFGAVKPLDDESTSWTKDILSFSDKPLGEVIATLTRYRNGVLRCDPAVA
                     GLRLSGTFPLKNTDAILNVIAQTLPVKIQSITRYWINISPL"
     gene            complement(8298..8819)
                     /gene="fecI"
                     /locus_tag="RHX21_004151"
     CDS             complement(8298..8819)
                     /gene="fecI"
                     /locus_tag="RHX21_004151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor FecI"
                     /protein_id="HDV1989262.1"
                     /translation="MSDRATTTASLTFESLYGTHHGWLKSWLTRKLQSAFDADDIAQD
                     TFLRVMVSETLSTIRDPRSFLCTIAKRVMVDLFRRNALEKAYLEMLALMPEGGAPSPE
                     ERESQLETLQLLDSMLDGLNGKTREAFLLSQLDGLTYSEIAHKLGVSISSVKKYVAKA
                     VEHCLLFRLEYGL"
     gene            9293..9397
                     /locus_tag="RHX21_004152"
                     /pseudo
     CDS             9293..9397
                     /locus_tag="RHX21_004152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477168.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         2233 a         2635 c         2724 g         2155 t
ORIGIN      
        1 accatgaaag cactggaaat ggcatgggaa acccgtggta agcccgtcgg ggtgatgttc
       61 caagcgatca aggcagtcat tatacgagca ggcagttccg gcagttactg tggcgatacc
      121 ggatcaggca gagtatgagt cggcgtggaa actgctggga taacagcccc atggagcgct
      181 tcttcaggag tctgaagaac gaatgggtgc cagcgacggg ctatgtaagc ttcagcgatg
      241 cagctcacgc aataacggac tatatcgttg gatattacag cgcactaaga ccgcacgaat
      301 ataatggtgg gttaccacca aacgaatcag aaaaccgata ctggaaaaac tctaacgcgg
      361 aggccagttt tagttgacca caacagacta cctgaaggga gccgcggtcg cctggcagtt
      421 gcagtagcag gagatcatcc agccgcagta caggtcacga tgactctggt taatgatacc
      481 ggctttgacc ccgtattttc cggctctatc gctgaatcat ggcgtcagca gccgtgcaca
      541 ccatcctatt gttgtgactg ggaggctgcc accatgcttc gcgctttccc tctggcgaaa
      601 aagggagaag gacgggcccg tctgccttca ctttatgcca gcttcggtaa gctgggtgag
      661 acaccgactc atgaagatat cattgataac aatcgatcca tcaactggcc tgtataacgt
      721 ggctgccggt gattaagaaa gctgcaccta cctaagtagt agcaaacgca cactttttag
      781 aaaaatcgat ggtcagaaac tggattagca attccgttcc agggttgctt ttgatttacg
      841 ttggcgtctg atcattgatt tatcctcaaa agcccaacct cattggtaat gaaccagctc
      901 cgtgaatgtc cgctctggca cagagcgaaa ttttttgatc tcccccctga aatctaaact
      961 tagtcatgtc acgtttttgg gtttctaaaa ttttaacttc gcgtttttcg ttgccgtaag
     1021 ggttatacag aaatgtccgt taagcagagt tcaaaattga ttgccgtgat cacgactggt
     1081 ttgaaagccg cgcccaagcc tgtacagctc tggtttgcgt tgattatgaa cctgtcagcc
     1141 taaagcaagc ggatggacga tgagtattgg taatctttca gagtccggaa aagttcagcc
     1201 ccagtctgaa caggcttgct ggcgccagtc cagtttcatt cagtcgtggt ttggttctta
     1261 cggcctgtgc aatctacctc attaggcaca tcggcctgcc agataccggc tcggggtgta
     1321 tttccgcttc cacgctgaat actgttctca gcaatcctgg ggtcatcacc tcttctggtg
     1381 tgccttgcgc cataacatgt ccgtttgcca ttaccaccag ttgatcgcag taccggctag
     1441 cctgattaag gtcgtgcagc acagcgacca ccgttttccc ctgagtccgg agttcgccca
     1501 tcaaccgcat caggtccacc tggtgattga tatcaagata ggtggttggc tcatcaagta
     1561 atacaacggg cgtattctgg gccaggacca ttgccagaaa tgcgcgctgg cgctgaccgc
     1621 cggaaagctc ggttaaccga cgaacggcaa gatgattgat ccgggtctgg ttcatggcga
     1681 cattaactcg tgcattgtct tcagcggaga gacgccccca gagtgacagc cagggattac
     1741 gaccatacga aaccagctcc tggactgtga tcccctctgg cgttaaatgg tgctgaggca
     1801 gcagcgaaag cctgcgggcc aactggcgcg atgagagcat atttatggga ttatcgccga
     1861 gaaatacggt gccagactgc ggcattaaaa gccgcgaaaa acagtttaac agcgtcgatt
     1921 tcccgcaacc gttaggaccg atcagggcgg tgatcttccc cgttggcagt gagagtgaaa
     1981 cgtcgttaag taccttgtct gtcccgtaac tgaccgtcag attttcagtt cgtaaagtca
     2041 tttatcgcat tctcacaagc aaccagacaa accacggcgc accgataatg gcggtcagca
     2101 cgccaaccgg gagctccagt gggggatgaa taattctcgc cagcagatcg gcaaccacca
     2161 acagcaacgc acctgtcagg gccgaaacag gcagcagtct gcggtgacgt ccaccggtga
     2221 tgctacgcat catatgcggc accacgagac caataaagct aatcgggccg caggcggcca
     2281 cgccggtaga tgtcatggcg acagctagta acaaagccca gaatcgggta tggggcaccg
     2341 acacaccgag cgtggtggcg cgcgcatcgc cgagtgcaag gaggtcgaga tcgcggcaaa
     2401 aactcaggct cagcggcaga aataaaatca tcagcgggat ggcaatcttc acaaagctcc
     2461 agtcacggcc ccataagctg ccggtcagcc acagcagggc gttgttcaca tcctgcgggc
     2521 gcgagagcat cagataatcc gtcaggctgg cccagcatgc agaaagcgcc acgccggtga
     2581 gcgccagctt catcggctgg tgggtctttg ccagcatctt cagcaatatc aaccccgcca
     2641 tgccgcccgc aaaggccagc agcggcagca ccatcacggg cagtgacggc ataagaagta
     2701 gagcccccac agaggccagg ctggcggcat ggttaacacc gagaatatcc ggtgatgcca
     2761 gagggttgcg cacaatcccc tgtatcagca cgcccgccac ggcgagggct gcaccgacaa
     2821 acagtgccag cagcaagcgc ggcagtcggt actccatcaa tacataataa tgctcgcgtc
     2881 cggcctgcca gtcggtcagc agcgcgcgcc acggcacggg gatcactccc atatggagtg
     2941 ataacagcgc acagcccgcc agggcaaggg tgatgaaaat aaccagcgca attttcatcc
     3001 tcgcctcctc acaagccaga caaagcaagg gctgccaatc agcgccagca ctgcgcctgc
     3061 gggcagatct ccggggaagg ccagtgcgcg tgcgagtaca tctgccagca gcatcagcgt
     3121 ggcccccagc agcatgctca ctggcagtac gttgcgctga tcgaagcctg cccagaagcg
     3181 cgccagatgt ggcaccagca gaccgataaa cgccaccgga cctgccacgc tgacgcacgc
     3241 accaaccaga agcagcacta acatattgat gaccaaacgt agcctcgtca ggttcactcc
     3301 cagcgtatgg gcggtgctgt cgctgaggtt gagcaggttc agttgattcg ccagcagcaa
     3361 cacgacaggg actgcagtga ccaccaccgg caagagctgc cagacatcct gccagcgggc
     3421 gtgggacact ccgcctgcca gccagtaaaa gatgccgtaa gcatgatctt cggccagcag
     3481 cagggtgatg cgggtaaggc ccatacaaaa ggccgacagc gcgatacccg cgaggatcag
     3541 tttgtttctg tcatgggtat gacgaaatcc gcctcctgcg gtcatgacca gcagccagct
     3601 cacgccgccc ccgcatgccg cgatgaacga cagagaatag cctgcaatcg gcgtcggact
     3661 cagcgcgctg gtaagcgcca tagccagcgc cgcgccgctg ttaatgccga gcagtgaagg
     3721 agaggccatt gggttgtggg tcagggtttg cagcagcgtg cccgcgagcg ccaggcttgc
     3781 gccgatcaga acggcgacca ggcttcgtgg caaacgaagg ttttgcacca gcgcttctgg
     3841 tagcgttggc gtgtgtccag gcagcagggc gcgggttgca tctgctccgg aaacaggaat
     3901 ggccgagtag caaaacagac tcagccagaa aataataata agtgctgcaa cgggaagccc
     3961 ccacagcagc accgggtgtt ttatcgcggt catttcacaa cggtaagcgg ctgatggtgg
     4021 aagattttta ccgtgtcagc ggcaatacgc tctgcagcaa aaataccgcg catccgcgcc
     4081 caggtgttac tgtcgaccga agcaacctgc tgcttctgcg cggcggttaa catctgccag
     4141 agcggatctt gttgccagcg tttaacaatg ctctcttcgc gatagtgggc aaccagcagc
     4201 caggcaggat tgaccgccag cagttgctcc aggccgatgg acggcatgga cgcacccgcc
     4261 atcgcagcgg gaacgttcag ccccagagag gccagcacgc tgccggtcca ggtctcctga
     4321 gtatgcaggt tgaattgctg ttcgcgtgat gtgccaaagg ccacgcgtgt ccctttggga
     4381 agctggctgg cccactgcgc catcctctct ttatgttgtt ccaggcgtgc ctgcatctct
     4441 cgctttttac ccaccatttc gccgatgata gccgcagatt gcaaattttc agcgtaggtt
     4501 tcgttgcggg acttaagcag cagtaccggc gcgatttgct gcaaggcgat gtaaaccccc
     4561 gcatggcgac tgctgtcggc aatgatcagg tctggtttca gagcggcaat ggcttccagg
     4621 ctcggctgcg cgcgcgttcc gacggactgc cacggtttca ggtgcgcacg cacttcgggc
     4681 aggatgcgtt ttgcatcgtt atcgtcggca ataccgatcg ggctgacgtc cacggcggcc
     4741 agcgcatcgg cgaacgagag ttccagcacc acaatccgtt gtggcgtttt ttcgagtgta
     4801 aacgtgccgt gttcgtcctg aaccatggcg gcaaaggcgt ggctgatcac cagcagcagg
     4861 cctgcaaaaa gaaaacggat aaatgccaac ataatcacat tccagctaaa agcccggcaa
     4921 gccgggcgtt aacacatcag aacttcaacg acccctgcat atacagcgtg cgcggctggc
     4981 ctgcatagat gcctttgttg ttgtcgtcat aagagcggat gaagtagtcc tggtcgaaga
     5041 tgtttttcac accgaatgcc aggttcagat ctgccatctg cgggccaaag tcatacgcca
     5101 cgcgtgcgcc ccagagcatg aagccgggaa tgcggccggt actgccgtcg gcgctctctt
     5161 tcaccgtatt ggcgttatcc gcaaactggc tggactggaa atcgctgttc agattgaacg
     5221 tccagtttcc tggcttgtag tccacgccca gcgtgccttt atgtttcggg gagaatggta
     5281 ccagattgcc gtaggtgtcg cctttctcgc ggatttccgc gttcacatac gcatagctgg
     5341 cgtagatgga aacgttatca agcgttggcg ttagcgtacc cagatcgtaa cgtgcctgcg
     5401 tttccagccc ggtatggcgc gttttgccac gtgcagtgac ggtgtcgttg gtctggttgg
     5461 agtcgtactg attgttaaag ttaatcagga acagccccat ttccgccgtc agcgcgccgt
     5521 cgtcgtagcg ggtaccgagt tcccaggttc gcgctttttc cggttccaca ttgccgcttt
     5581 gcacagcctt gccaatctgg ctgtactgta cggtgccgaa cgagccttca gtgtttgcat
     5641 aaagattcca gctgtcagtc aggtgataga gcacgttcaa cgccggaagc ggtgcgttat
     5701 agctcacttc ttcgtgcgtg cctgtgatgg cgttgttctg gtatgactcg atatgttcga
     5761 aacgcatacc cggcgtgatg gtccagttgc cgatgtcgat tttgtcatcc agataccagg
     5821 cgtgcgcctc ggtgccggaa cgcgtatcgc ggtcgtaagg gcttgagccg gacggcaact
     5881 gcccgctgct ggtggcggtg tagtaacgca tttcatgcgt tgattcattc aaatagcgat
     5941 agcccacgcc cacttcgtgc gcggaagggc cgatcataaa gatctggctg tagcgtggct
     6001 caataccgcg cacccagtag ttacgcggcg agagggtgat gcgtttgcct tgctccaggt
     6061 agccgctgcg cagggtttgg gtgtagaacc cctgaatgtt gaatttatgc tggctgtctg
     6121 gctggaactg gtagcccagg ctcgccagct tgcgacgacc ccagaagcgg tcatacgggc
     6181 gggtggattg ccagcgatcg gcgtcgtaat ccgcgcgaga caggccaccg ggcatgtcgg
     6241 cttcaccgtc gtaatattgc agcaggctgt tgaaggtgtg cacctcatcc ggcgcatatt
     6301 tgcttttcag catcaggtcg tcgatgcggg tggcgctgtg ctcgcgccag tcactgccgc
     6361 gcgtgccgga gtagagcagc gcggtgccaa aaccgttgtc cgctgtgccg cccaccatca
     6421 ggttgtgcgt ctctttcggg ttgttttgtg aagaggttgg gctgagctga ccttccacgc
     6481 ccgcctcgat accaaagtcc tgcggaatgg cacgggtaac aaagttcacc acgccgccca
     6541 cgctctgcgg tccgtaacgc accgcaccac caccgcgtac cacgtcaatg gcatccatgt
     6601 tgccgagcga aacgggagcc agtgaaagct gcggctgacc gtaaggggcg aaggggacgg
     6661 ggatgccgtc catcaggacg gtcgagcggc tggcgaggcg cgggttcagg ccccggatgc
     6721 caaagttcat cgccaggtcg tggctgccgg tgccgttgtt ttccggcgcg ctgacgccag
     6781 ggatgcggtt aagtacctca cgcatggtgg ttgcgccggt tttggcgaaa tcctcacggc
     6841 ggatcacgtc acgcgcgcca gcatgttcaa atacgtcgtt ttcacgcgca tcacccagcc
     6901 agtcgccgac cacggtcagg gcatcttctt ttggtgcggg cgcgggctcc agcgtccagc
     6961 tgttatttcc cagcggtttt acctgcagtc cgctgccgtc cagcagttgt tgcaggccgc
     7021 tctcgacgtc gtaatcgccg tgcaggccgt tgctctgctt gccgcgcgtc aggctggcgt
     7081 caaccgagag ggtaaatccg ctgtgtgcgg catactgatt gagcgcttta tcgagcgatc
     7141 ccggtgcgat attaacctgt gcagcaaaag cggaaaacga gagaccggcc agcggcagca
     7201 ggctcaggcg aatggtgtta accaaaggtg ttgttttacg aaaaacgcgt aacggcgtca
     7261 taccttcccc atcatcattt ttgttgtgtt cagctatgag tcgaacgaga agggtaaaaa
     7321 ggacaatcga aataagaatt attttcctta cagtggtgaa atgtttatcc agtaccgcgt
     7381 aatagactga attttaacgg gaagcgtttg cgcgataacg ttcaggatcg catcggtatt
     7441 tttcagcggg aacgtcccgc tcaggcgcag cccggcaacg gcgggatcgc agcgcagcac
     7501 gccgttgcgg taacgggtta gcgtggctat cacctcaccc agcggtttat cgctgaagct
     7561 caggatgtcc ttcgtccagc ttgtactctc gtcatccagc ggtttcactg cgccaaactc
     7621 agaggcgctg aactgcaggc tttcaccagc gttcacgatg cgtttttgcg cgggggcact
     7681 ggcgagaagc acttccacag cgtgctgctg cacgtcaagc tgcgtgaaat tatcctgctg
     7741 gcggacggta aattctgtcc ctaaagcagt gagctggccc tgacgggtca ggacacggaa
     7801 ggggcgttgc agggcatctt tcgcggtagt aatggcgatt tcaccgtacc agagccggac
     7861 ggtgcgctga tgcgcatcaa aacgcacatc cgccgcgctt tgggtattca gcgtgagcag
     7921 ggagccatct tccagttgct gacggctgac tgtgcctttg gcggtgcggt aatctgcccg
     7981 cagaccttcg ccggtttccg actgccagag ctgccagcct ccgccagcgc cgagcaacag
     8041 cagtaatcct ttcatcacgt gacggcgggt gaggcgggta tcgtgcaacg cccggctggc
     8101 aacgtcgcca ggcacaccgc caagctggtt gcgcaggttt tcaacctgct gccaggccca
     8161 ctggttatcc tgatcctgtt cataccactg ttgccagcgc gcttcctgtt gtgggctgac
     8221 gcgctcgccg cttagcacgg cataccagtg ggaagctgaa cgcagcgcct gacggcggga
     8281 atcggttaac aaaggattca taacccatac tccagacgga acagcaggca gtgctcgacg
     8341 gctttcgcca cgtatttttt cacggagctg atggaaacac cgagtttgtg cgcaatctcg
     8401 ctgtatgtca gaccatccag ttgcgaaagc agaaacgctt cacgtgtttt gccgtttagc
     8461 ccgtccagca tgctgtcgag gagttgtagg gtctcgagtt ggctttcgcg ttcctcaggt
     8521 gaaggcgctc ccccctccgg cataagcgcc agcatctcca gatacgcttt ttccagcgcg
     8581 tttcggcgaa acaggtccac catcacgcgt ttggcgatag tgcagaggaa ggagcgagga
     8641 tcgcggatcg tcgagagcgt ttcgctgacc attacccgca aaaaagtgtc ctgggcaatg
     8701 tcatctgcat caaaagcaga ctggagtttg cgcgtcagcc agcttttcaa ccagccgtga
     8761 tgtgtgccat aaagcgactc gaacgttaag gaagctgtgg tagtggcgcg gtcagacatg
     8821 cggagtgcat caaaagttaa ttatcacgta gtcatattaa tatgagaatg gttatcatta
     8881 caattggaaa taaaattgtt tccaatagac atttttaaca tgttgttttt ctaagtgtta
     8941 taaggtaggt ataaaatggg atggagcctc tgcttctggc atgtgtcggt cagaatgact
     9001 catgatgtgg tctgctatta ttgacatcct cactgcccta aaggatgggg atttcggtaa
     9061 tgatcttacc cagcaatagt ggacacgcgg ctaagtgagt aaactctcag tcagaggtga
     9121 ctcacaagac aaaacagttt caaccagtaa aaaaacgtaa acaccattcg catgaatttc
     9181 gtagttaaga tctgaagctt gcagaatgca tcggtgttac tgccggagtc cgttaactta
     9241 gtctgcatga atcaccacag ctttacatct gtcgcagtaa acagcaaaat cagcaaactt
     9301 acttaattat atcgagtgcg attacaatcg ctggcgatgg tacagttggt gtggcggtct
     9361 cagtccggaa caatttgaaa atcagaatct cacttaaaac ggcatccatt ttacaaaaga
     9421 tggccgtctg tgtatttata atgaatacct tctacatgtt tagagtgcat aatccacgac
     9481 aaggcgatat cctaaaaatt agctagcagg caactttgat ggcatagata atgtttttag
     9541 taaaaaagag ttgactgaat ataatacagc ctcttcctac ataagaagga atgtgctcac
     9601 aaaaaaaacc attagtctgc ttcctgttct tacaataatc agtattatgt attttattta
     9661 tatagcaaaa tatgcttgtt acacctgtca taattaggca tggtaaaatt attgactgaa
     9721 ccctggggga gaaagatgca cagtgat
//
LOCUS       DAPGUL010000153         9376 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.156, whole genome shotgun sequence.
ACCESSION   DAPGUL010000153 DAPGUL010000000
VERSION     DAPGUL010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9376
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.156"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(80..2071)
                     /gene="tkt"
                     /locus_tag="RHX21_004153"
     CDS             complement(80..2071)
                     /gene="tkt"
                     /locus_tag="RHX21_004153"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDV1989263.1"
                     /translation="MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDF
                     LKHNPQNPSWADRDRFVLSNGHGSMLIYSLLHLTGYDLPMEELKNFRQLHSKTPGHPE
                     VGYTAGVETTTGPLGQGIANAVGMAIAEKTLAAQFNRPGHDIVDHYTYAFMGDGCMME
                     GISHEVCSLAGTLKLGKLIAFYDDNGISIDGHVEGWFTDDTAMRFEAYGWHVIRDIDG
                     HDAASIKRAVEEARAVTDKPSLLMCKTIIGFGSPNKAGTHDSHGAPLGDAEIALTREQ
                     LGWKYAPFEIPSEIYAQWDAKEAGQAKESAWNEKFAAYAKAYPQEAAEFTRRMKGEMP
                     SDFDAKAKEFIAKLQANPAKIASRKASQNAIEAFGPLLPEFLGGSADLAPSNLTLWSG
                     SKAINEDAAGNYIHYGVREFGMTAIANGISLHGGFLPYTSTFLMFVEYARNAVRMAAL
                     MKQRQVMVYTHDSIGLGEDGPTHQPVEQVASLRVTPNMSTWRPCDQVESAVAWKYGVE
                     RQDGPTALILSRQNLAQQERTEEQLANIARGGYVLKDCAGQPELIFIATGSEVELAVA
                     AYEKLTAEGVKARVVSMPSTDAFDKQDAAYRESVLPKAVTARVAVEAGIADYWYKYVG
                     LNGAIVGMTTFGESAPAELLFEEFGFTVDNVVAKAKELL"
     gene            2349..3107
                     /gene="loiP"
                     /locus_tag="RHX21_004154"
                     /gene_synonym="yggG"
     CDS             2349..3107
                     /gene="loiP"
                     /locus_tag="RHX21_004154"
                     /gene_synonym="yggG"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311838.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease LoiP"
                     /protein_id="HDV1989264.1"
                     /translation="MKIRALLVAMSVATVLTGCQNMDSNGLLSSGAEAFQAYSLSDAQ
                     VKTLSDQACQEMDSKATIAPANSEYAKRLTTIANALGNNINGQPVNYKVYMAKDVNAF
                     AMANGCIRVYSGLMDMMTDNEVEAVIGHEMGHVALGHVKKGMQVALGTNAVRVAAASA
                     GGIVGSLSQSQLGDLGEKLVNSQFSQRQEAEADDYSYDLLRQRGISPAGLATSFEKLA
                     KLEEGRQSSMFDDHPASAERAQHIRDRMSADGIK"
     gene            complement(3313..4233)
                     /gene="speB"
                     /locus_tag="RHX21_004155"
     CDS             complement(3313..4233)
                     /gene="speB"
                     /locus_tag="RHX21_004155"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HDV1989265.1"
                     /translation="MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDM
                     ATSGRAGGRHGPAAIRQVSTNLAWEHNRFPWNFDMRERLNVVDCGDLVYAFGDAREMS
                     EKLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCE
                     FDHGTMFYTAPKEGLIDPNHSVQIGIRTEFDKDNGFTVLDACQVNDRSVDDVIAQVKQ
                     IVGDMPVYLTFDIDCLDPAFAPGTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVA
                     PAYDQSEITALAAATLALEMLYIQAAKKGE"
     gene            complement(4369..5100)
                     /locus_tag="RHX21_004156"
     CDS             complement(4369..5100)
                     /locus_tag="RHX21_004156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989266.1"
                     /translation="MKKWKVRSALVALIVLLAGCSSNAQYNSSASGNVGTAWGGDVHS
                     SVQGVSAERAWRDPAEMIVISYSTNVPSGYDRVYSIRINELEYAIRDGNFNSLPITRV
                     YDSSNNEPRYIVHARVGMNYQLYVRNYSRNTNYEIVATVDGLDVLNGKQGSLNNNGYI
                     VNAGDSLAIKGFRKDKHTEAAFQFANVADSYAANSAQGDVRNTGVIGFAAFELQGQAQ
                     NALPPCSGQAFPADNNGYAPPPCRK"
     gene            complement(5246..7222)
                     /gene="speA"
                     /locus_tag="RHX21_004157"
     CDS             complement(5246..7222)
                     /gene="speA"
                     /locus_tag="RHX21_004157"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic arginine decarboxylase"
                     /protein_id="HDV1989267.1"
                     /translation="MSDDMSMGLPSSAGEHGVLRSMQEVAMSSQEASKMLRTYNIAWW
                     GNNYYDVNELGHISVCPDPDVPEARVDLAQLVKTREAQGQRLPALFCFPQILQHRLRS
                     INAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLA
                     HAGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIVLDEAERLNVVPR
                     LGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLREAGRLDSLQLLHFHLGSQ
                     MANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNE
                     YANNIIWAIGDACEENGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTVPTAPAE
                     DAPRALQSMWETWQEMHEPGTRRSLREWLHDSQMDLHDIHIGYSSGTFSLQERAWAEQ
                     LYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFPVL
                     PLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVG
                     AYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTQF
                     RDQVKKTDLDAELQQQFLEEFEAGLYGYTYLEDE"
     gene            complement(7231..7362)
                     /gene="yqgB"
                     /locus_tag="RHX21_004158"
     CDS             complement(7231..7362)
                     /gene="yqgB"
                     /locus_tag="RHX21_004158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417414.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid stress response protein YqgB"
                     /protein_id="HDV1989268.1"
                     /translation="MKKKPVAQLERQHSLLENPCAYGLLSQFQAAIVVNCFTLNKII"
     gene            7498..7713
                     /locus_tag="RHX21_004159"
     CDS             7498..7713
                     /locus_tag="RHX21_004159"
                     /inference="COORDINATES: protein motif:HMM:NF037550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989269.1"
                     /translation="MGITSAGMQSRDAECGERIFTRTVRQVKQQTTVHYFVSPPRPPV
                     KTNPQAKTLISTRLEVATRKKRRVLFI"
     gene            8017..9171
                     /gene="metK"
                     /locus_tag="RHX21_004160"
     CDS             8017..9171
                     /gene="metK"
                     /locus_tag="RHX21_004160"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HDV1989270.1"
                     /translation="MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACET
                     YVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPD
                     INQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPW
                     LRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLT
                     SATKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAA
                     YAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPSEQLTLLVREFF
                     DLRPYGLIQMLDLLHPIYKETAAYGHFGREHFPWEKTDKAQLLRDAAGLK"
BASE COUNT         2315 a         2512 c         2382 g         2167 t
ORIGIN      
        1 atctattgct tgtccgcaaa cggacatatc aaggtaataa aaaaggtcgc cgaagcgacc
       61 tttttacccg aaatgctaat tacagcagtt cttttgcttt cgcaacaacg ttatcaacag
      121 tgaagccgaa ctcttcaaac agcagctctg ccggagcaga ttcaccgaag gtggtcatac
      181 cgacgatagc accgttcagg ccaacatact tgtaccagta gtcagcaata cccgcttcta
      241 cagcaacgcg tgcagtaacc gctttcggca gtacggattc acggtaagca gcatcctgct
      301 tgtcaaatgc gtcggtagac ggcatggaca ccacgcgcgc tttcacgcct tcggcagtca
      361 gtttttcgta ggcagcaaca gccagttcaa cttctgaacc ggtagcgatg aaaatcagtt
      421 ccggctgacc ggcgcagtct ttcagcacat aaccaccgcg cgcgatgttt gccagttgct
      481 cttcagttcg ttcctgctgc gccaggttct gacgggagag gatcagtgcg gtcgggccgt
      541 cctgacgctc aacaccgtat ttccacgcga ccgcggattc aacctggtca cacggacgcc
      601 atgtagacat gttcggggtt acgcgcagag aagcgacctg ctctaccggc tggtgagtcg
      661 ggccatcttc gcccagaccg atggagtcgt gggtgtaaac catcacctga cgctgtttca
      721 tcagcgcagc catacgtacg gcgttacgtg cgtattccac gaacatcagg aaggtggagg
      781 tgtacggcag gaaaccaccg tgcagggaga taccgttagc aatcgcggtc ataccgaact
      841 cgcgaacacc gtagtggatg tagttacccg cagcatcttc gttgattgct ttagaaccag
      901 accacagggt caggttagac ggtgccaggt cagcagaacc gccgaggaat tccggcaaca
      961 gcggaccgaa agcttcgata gcattctgag acgctttacg gctggcgatt ttcgccgggt
     1021 tagcctgcag tttagcaatg aactcttttg ctttcgcgtc gaagtcagac ggcatttcgc
     1081 ctttcatacg gcgggtaaat tcagcggctt cctgcggata agctttcgcg taagcagcga
     1141 atttctcgtt ccatgcggat tctttcgcct ggcctgcttc tttcgcatcc cactgagcat
     1201 agatttcaga cgggatttcg aacggtgcat atttccagcc cagctgttcg cgggtcaggg
     1261 caatttcagc gtcgcccagc ggcgcaccgt gggagtcgtg agtaccggct ttgttcgggg
     1321 aaccgaaacc gatgatggtt ttgcacatca gcagggacgg tttgtcagtc actgcgcgcg
     1381 cttcttctac tgcgcgtttg atggatgccg cgtcatgacc gtcgatgtcg cgaataacgt
     1441 gccagccgta agcttcgaaa cgcattgcgg tgtcgtcggt gaaccagcct tcaacgtgac
     1501 catcaataga gataccgttg tcatcgtaga acgcaatcag tttacccagc ttcagcgtac
     1561 ccgccagaga gcaaacttcg tgggagatgc cttccatcat gcagccgtcg cccatgaagg
     1621 cataggtgta gtggtcgaca atgtcgtggc ccggacggtt aaactgcgcc gccagcgttt
     1681 tttctgcaat cgccataccg actgcgttgg caataccctg acccagcgga ccggtggtgg
     1741 tttccacacc agcggtgtaa cccacttccg ggtgacccgg agttttagag tgcagctgac
     1801 ggaagttttt cagttcttcc atcggcagat cgtaaccggt gaggtgcagc aggctgtaga
     1861 tcagcatgga gccgtggccg ttggacagca cgaagcggtc acggtcagcc caggacggat
     1921 tctgcgggtt gtgtttcagg aaatcacgcc acaggacttc ggcaatgtca gccataccca
     1981 taggggcacc cgggtgaccg gatttggctt tctgtactgc gtccatgctc agcgcacgaa
     2041 tagcattggc aagctcttta cgtgaggaca ttttgactcc agatcggatg atgaagggca
     2101 cgcccttaac gacttgacga cagcgcgttt tgggctacgc cggaaaattt gccaacaatt
     2161 taccgcaagc cgcgcgtcat gtacatggaa catccttttg ccgcttcaga aatctctgga
     2221 tcatgctcgc atgttgcgca atctactcgc ccgtccgctg cgcttttcct tatactgaga
     2281 ctgagcgtcg attcacctgc aaacggcgca tttttagaat aatcctgacc ttgtgcggaa
     2341 gagaaaacat gaaaattcgc gccttattgg tagcaatgag cgtggcaacg gtactgactg
     2401 gttgccagaa tatggactcc aacggactgc tctcatcagg agcggaagct tttcaggctt
     2461 acagtttgag tgatgcgcag gtgaaaaccc tgagcgatca ggcatgtcag gagatggaca
     2521 gcaaggcgac gattgcgcca gccaatagcg aatacgctaa acgtctgaca actattgcca
     2581 atgcgctagg caacaatatc aacggtcagc cggtaaatta caaagtgtat atggcgaagg
     2641 atgtgaacgc ctttgcaatg gctaacggct gtatccgcgt ctatagcggg ctgatggata
     2701 tgatgacgga taacgaagtc gaagcggtga tcggtcacga aatggggcac gtggcgttag
     2761 gccatgtgaa aaaaggaatg caggtggcac ttggtacaaa tgccgtgcga gtagctgcgg
     2821 cctctgcggg cgggattgtc ggcagtttat ctcaatcaca actcggtgat ctgggcgaga
     2881 aattagttaa ttcgcaattc tcccagcgcc aggaagcaga agccgatgat tattcttacg
     2941 atcttctgcg ccaacgcggc atcagcccgg caggtcttgc caccagcttt gaaaaactgg
     3001 cgaaactgga agaaggccgc caaagctcaa tgtttgacga ccatcctgca tccgccgaac
     3061 gcgcccagca tattcgcgat cgtatgagcg cggatgggat aaagtaaagc ctggtggtgt
     3121 cgaacgtagg tcagataagg cgttcacccc gcatctgaca tgaatggcac atttgttacc
     3181 ttgtgcgcat tgccggatgc gatgctggcg catcttatcc ggcctacggg tgccgaacgt
     3241 aggtcggata aggcgttcac gccgcatccg acattaatgg cacgttttac ccgtgcgcat
     3301 cgcatctggt gcttactcgc cctttttcgc cgcctgaata tacagcatct ccagcgccag
     3361 cgtcgccgca gccagagcag tgatttccga ctgatcgtat gccggagcca cttccactac
     3421 gtccatccca acgatgttga gatctttcag gccgcgtacc agtttaatgg cgcgatcgga
     3481 ggtcagaccg ccaattaccg gcgtaccggt tcccggcgca aatgcaggat ccaggcagtc
     3541 gatatcaaag gtcaggtaaa ccggcatatc acccacaatt tgtttcacct gggcgataac
     3601 gtcatccacg ctgcgatcgt tcacctggca ggcgtccagc acggtaaagc cgttgtcttt
     3661 atcaaattcg gtacgaatac caatctgcac ggaatgattc ggatcgatca gaccttcttt
     3721 cggcgcggta tagaacatgg tgccgtggtc aaattcacaa ccgttcgcgt aggtatcggt
     3781 gtgggcgtca aagtgtacca gcgccatttt gccgaaatgc ttcgcatgag cacgcagcag
     3841 cggcagcgta acaaagtggt caccaccgaa ggagagcata cgcttaccgg cagccagcag
     3901 cttctcggcg tgcgcctgca gcttctcgct catctcacgg gcatcgccga aagcatatac
     3961 cagatcaccg cagtccacga cgttcagacg ctcacgcatg tcgaaattcc acgggaagcg
     4021 gttgtgttcc caggccagat tcgtcgaaac ctgacggata gctgccggac cgtggcgtcc
     4081 ccccgcacga ccagaagtgg ccatatcgaa cggcacacca gtaatcaccc agtcagcatc
     4141 gctgtcatac ggctggaagt tcatcggcag gcgtaaaaaa ccaaaggcat tggaaaccag
     4201 tgagttatcg tattgatgac ctaaggtgct catggatgga ctcctattac aaagtcgata
     4261 taaaaaaacc cttccgcgtc gttaggcccg acgaggaagg gttggatttg cgaaacacaa
     4321 gtttgtgcta attatcgcct taaatgggcg aggcatcaag cgaggttgct atttccgaca
     4381 cggtggcggc gcatagccat tgttatctgc cggaaaggct tgtccagagc acggcggcag
     4441 cgcgttttgc gcctggcctt gtaattcaaa ggcggcaaag cctattacac cggtattacg
     4501 cacatcgcct tgcgccgaat tggctgcgta ggaatcagca acgttggcga actgaaaagc
     4561 cgcttcggta tgtttatctt tgcggaatcc tttaatcgct aaagaatctc cggcattcac
     4621 aatatagccg ttgttattca gcgaaccttg cttgccgttc agcacatcca ggccatcaac
     4681 agtagcaacg atctcgtagt tggtgttacg actgtaatta cggacatata attgataatt
     4741 cattccgact ctggcatgga caatatagcg tggttcatta ttggatgaat cataaacacg
     4801 cgtaataggt agagaattaa aattaccatc gcgaatagca tattccagtt cgttaatacg
     4861 aatgctataa acgcggtcat agccggaagg aacattagtc gaataactaa taacgatcat
     4921 ctctgccgga tcgcgccagg ctcgctcagc agatacgccc tgaaccgatg agtgcacatc
     4981 cccaccccag gcagtgccga cattgcccga tgcactgcta ttatactgcg cattactgga
     5041 acaaccggcc agcagcacga ttaatgccac caacgcgcta cgtactttcc attttttcat
     5101 aaccgttccc tctgcattta attaatgcag cgattgtagg gagattattt aataagaaaa
     5161 gcagcgagat tatttttaag aatatataaa aagaaagcgg gccgatttac gtaaataaat
     5221 cgacccgcca gcggaataat cttaattatt catcttcaag ataggtataa ccgtacaaac
     5281 ctgcctcgaa ctcttcaagg aactgttgtt gcagttcagc atcaagatcg gttttcttca
     5341 cttgatcgcg gaactgggtt aacagcgttt tcggatcgag ctgtacatat tgcagcatgt
     5401 ccgccacggt atcgccttcg tcagacagtt ctacttctac gctaccgtca gggaacacga
     5461 acacgtcaac cgcttcggta tcaccgaaca ggttgtgcat attgccaagg atctcctgat
     5521 atgcgccgac cataaagaaa ccgagcatcg gcggattctc tggatcgtac tccggcattg
     5581 gcattgtcgt ggcaatacca tcaccatcaa tatagtggtc gatagcaccg tcagagtcac
     5641 aggtaatatc cagcagcaca gcgcgacgtt ccggcacttg atccagccct tccagcggca
     5701 gaaccgggaa caactggtcg atcccccatg cgtccggcat tgactggaac agcgagaaat
     5761 tgacgtacat tttgtccgcc atacgttcct gcagttcgtc gattatcgga cgatgcgcac
     5821 ggttttgcgg atccagttgc ttctgcactt catggcacat gctcagatag agttgttctg
     5881 cccatgcacg ttcttgcagg ctaaaggtgc cggaagagta gccgatatga atgtcgtgca
     5941 gatccatctg actgtcgtgt aaccattcac gcagagaacg gcgagttccc ggttcgtgca
     6001 tctcctgcca ggtttcccac atgctttgca gcgcgcgcgg cgcatcttct gcaggcgcgg
     6061 tcggcaccgt gtattcgtta cgttccacgc cgatgatatt agacaccagc acggtgtgat
     6121 gcgcagtcac cgcacgaccc gattcggtga ttaccgtcgg atgcggcaga ccgttttctt
     6181 cacacgcatc accaatcgcc cagatgatgt tgttggcata ttcattgagg ccgtagttta
     6241 cggagcagtc agactgcgaa cgggtgcctt catagtccac gcccagaccg ccgccgacgt
     6301 cgaagcactg aatattgacg cccagcttgt gcagttccac atagaaacgc gccgattcac
     6361 gaacgcctgt ggcgatatcg cgaatattcg ccatctgcga accgaggtgg aagtgcagta
     6421 gttgcaggct gtcgagacgc ccggcttcac gcagggtttc aaccagttgc agtacctgag
     6481 tcgcagccag gccgaacttc gatttttccc cgccggagga ctgccattta cccgagccct
     6541 gcgaagccag acgtgcacgc acgcccagac gaggaacgac attcagacgt tctgcttcat
     6601 ccagcacaat ggcgatttct gacatcttct caatgaccag atagaccttg tgccccatct
     6661 tctcgccaat taatgccagg cggatatatt cgcggtcttt ataaccgttg cagacgatga
     6721 cgctacgggt catgccagca tgtgccagca ctgccatcaa ctcggctttg gaaccggctt
     6781 ccagacccag cggttcgccc gaatgaatca gggactcaat cacgcgacgg tgctggttaa
     6841 ctttgatcgg ataaacaagg aagtaatcgc cgttatagcc gtaggattcc cgcgcacgtt
     6901 tgaacgcggc gttaatggaa cgcaaacggt gctgcaggat ctgtgggaaa cagaacagtg
     6961 caggcagacg ctggccctgt gcttcacgag ttttcactaa ctgcgcgaga tcgacgcgag
     7021 cttccgggac gtccgggtcc gggcacacgc tgatgtggcc cagctcgtta acgtcatagt
     7081 agttattgcc ccaccaggca atattgtaag tacgcagcat cttgctggct tcctgggagc
     7141 tcattgcaac ctcctgcatg gagcgtagta caccgtgttc gcccgctgac gaaggcaaac
     7201 ccatagacat gtcgtcagac atagcgaacc tcaaattatt ttattaagtg taaaacagtt
     7261 aacgactatc gcagcctgga actgcgataa caacccataa gcacatggat tttccagcag
     7321 tgaatgctga cgctccaact gcgcaaccgg tttctttttc ataacattat taagcacata
     7381 accgaacgta agtgtgacag ttcggcgaaa ccacgagaaa actcttgttt ttacaagagc
     7441 gcccttgttc agtcctcagt aactgtaacc agctcttgaa tcctgagaag cgccgagatg
     7501 ggtataacat cggcaggtat gcaaagcaga gatgcagagt gcggggaacg aatcttcacc
     7561 agaacggtga gacaggttaa gcagcagaca acggttcatt atttcgtatc acctccacgg
     7621 ccgcctgtta agacgaaccc acaagccaaa actctgattt caacccggct ggaagtggca
     7681 acacgaaaga aacgtcgtgt gctttttatt taagccgcgc gccgcgtttt ataccccaca
     7741 atggcagaaa attgcaaaag ataaatacgc agaatgccgg cattgtcagg aaaaatttcc
     7801 agccacgttt ttaacagaat gagacacgat tcaaaaaaaa gtggaaatcg ggtgaagaat
     7861 tgacctaaaa tagccatcca gatgttaatc catccatacc gattaacact cagactgcca
     7921 gtgtttttaa cctgcagagt cgtggtagga tccgctacca cagaaaatcc acacaacagt
     7981 ttgagctaac caaattctct ttaggtgata ttaaatatgg caaaacacct ttttacgtcc
     8041 gagtccgtct ctgaagggca tcctgacaaa attgctgacc aaatctctga tgccgtttta
     8101 gacgcgatcc tcgaacagga tccgaaagca cgcgttgctt gcgaaaccta cgtaaaaacc
     8161 ggcatggttt tagttggcgg cgaaatcacc accagcgcct gggtagacat cgaagagatc
     8221 acccgtaaca ccgttcgcga aattggctat gtgcattccg acatgggctt tgacgctaac
     8281 tcctgtgcgg ttctgagcgc tatcggcaaa cagtctcctg acatcaacca gggcgttgac
     8341 cgtgccgatc cgctggaaca gggcgcgggt gaccagggtc tgatgtttgg ctacgcaact
     8401 aatgaaaccg acgtgctgat gccagcacct atcacctatg cacaccgtct ggtacagcgt
     8461 caggctgaag tgcgtaaaaa cggcactctg ccgtggctgc gcccggacgc gaaaagccag
     8521 gtgactttcc agtatgacga cggcaaaatc gttggtatcg atgctgtcgt gctttccact
     8581 cagcattctg aagagatcga ccagaaatcg ctgcaagaag cggtaatgga agagatcatc
     8641 aagccaattc tgcccgctga atggctgact tctgccacca aattcttcat caacccgacc
     8701 ggtcgtttcg ttatcggtgg cccaatgggt gactgcggtc tgactggtcg taaaattatc
     8761 gttgatacct acggcggcat ggcgcgtcac ggtggcggtg cattctctgg taaagatcca
     8821 tcaaaagtgg accgttccgc agcctacgca gcacgttatg tcgcgaaaaa catcgttgct
     8881 gctggcctgg ccgatcgttg tgaaattcag gtttcctacg caatcggcgt ggctgaaccg
     8941 acttccatca tggtagaaac tttcggtact gagaaagtgc cttctgaaca actgactctg
     9001 ctggtacgtg agttcttcga cctgcgccca tacggtctga ttcagatgct ggatctgctg
     9061 cacccgatct acaaagaaac cgcagcatac ggtcactttg gtcgtgaaca tttcccgtgg
     9121 gaaaaaaccg acaaagcgca gctgctgcgc gatgctgccg gtctgaagta atctttcttc
     9181 acctgctttc aaaggccagc ctcgcgctgg cctttttctt ttacctcacc gcggtggata
     9241 ggcattcacg ccgcatccgg caaaaagctg cccgcacaat aacatcattc ttcctcaaca
     9301 cgttttatcg caaattatca tcactactga aaccgattac accaataaca ccagccaaat
     9361 atttgtaata ttttca
//
LOCUS       DAPGUL010000154         9315 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.157, whole genome shotgun sequence.
ACCESSION   DAPGUL010000154 DAPGUL010000000
VERSION     DAPGUL010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9315
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.157"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            398..1324
                     /locus_tag="RHX21_004161"
     CDS             398..1324
                     /locus_tag="RHX21_004161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989271.1"
                     /translation="MSKKYQPLLITHYMSTWVTITEAVEITTKAIKQKITPSDIYRHA
                     LSGNILLSVYFQSPVILKKIQTFNGKIKFRQFEGDLLDKLCMLDRDGFIYGQNLRLCT
                     EARYVCPVQQIIDTPLIGYEYVLIQRILARELKFPSPIVGARKTNHGIIVRFSEELFQ
                     IFETMSWKERVEKQISRLPKNTALDVIKKLTEVTTIKYNHNGCFPLYTLPPDACFVIR
                     HTEVERLINLYKKRESHPISPSRMTTPLSRLFWLACKHNDIISPLLNHPYKLLSIFEQ
                     WASGDGIGEKLDAETLKNALKRGSPSSTSLSG"
     gene            1464..1649
                     /locus_tag="RHX21_004162"
     CDS             1464..1649
                     /locus_tag="RHX21_004162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
                     /protein_id="HDV1989272.1"
                     /translation="MTSYQLLRLRQVEQKTGLKRSQIYLYMKEGAFPRSIKIGPASVA
                     WLESEIDEWINKKLSDR"
     gene            1671..1853
                     /locus_tag="RHX21_004163"
     CDS             1671..1853
                     /locus_tag="RHX21_004163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001309570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989273.1"
                     /translation="MNINIPALINFDPAGIKKSTCMYISDLPGIVLYDTIPFTEYSAE
                     LLSTYSVKESISCFHP"
     gene            1838..2419
                     /locus_tag="RHX21_004164"
     CDS             1838..2419
                     /locus_tag="RHX21_004164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2857 domain-containing protein"
                     /protein_id="HDV1989274.1"
                     /translation="MLPSLNHIILTVALQALREGNIHHCETMGFTYDEMNLLGCLSIN
                     DLITLSQAPLPLVDITIRHDVLQKLLASSHEENRRQEQLNRAVRLGGSIALMNRYFGV
                     GSRETCARRRLLGVSVPNGRTPIPDEETDAAIWHQWQKYRVENIDSPEALDAMMLVTE
                     NLSSCTAPSLTVVWNCITHCERKNTVRRIQRAR"
     gene            2409..2618
                     /locus_tag="RHX21_004165"
     CDS             2409..2618
                     /locus_tag="RHX21_004165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA family transcriptional regulator"
                     /protein_id="HDV1989275.1"
                     /translation="MPDEIDRDQAFNERCLEALIEQSRLRPTPTPSLQHCRLCGKAIP
                     EKRRQTLPGVTTCTDCQSILEKRRR"
     gene            2822..2989
                     /locus_tag="RHX21_004166"
     CDS             2822..2989
                     /locus_tag="RHX21_004166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989276.1"
                     /translation="MNDGSLLEKVVGHMEEKLTGNELEMLYAAADYRRAEIVMNQYFD
                     KVPGNVWKYVR"
     gene            3558..3791
                     /locus_tag="RHX21_004167"
     CDS             3558..3791
                     /locus_tag="RHX21_004167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989277.1"
                     /translation="MRKPVYYAYVAQESHPDSQGEKNTWWTKVGVAFPHHGKSGLNIV
                     LTPGIAVSGKLVLLEPREENNPPQNTGPIETVS"
     gene            3864..4574
                     /locus_tag="RHX21_004168"
     CDS             3864..4574
                     /locus_tag="RHX21_004168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HDV1989278.1"
                     /translation="MLSTTAFLAIAMQCAASIHPSTAFDVARVESGFNPYAIAEIVPK
                     AGPSFGDQHIISHLPASRGDAEHILRRLSAQDRRYSVGLMQITSTNFRHYGVSATELL
                     DPCTNLSVFEHILRDCYRRGGTLKRALSCYYSGNFSTGQQPETAFSGTSYIQRIGYPP
                     GSSRYAVPGTREDKSSVAVPLKTAPASDSSRHHVFWPGVVVRGVPAKLRQEKIFIAPF
                     SAPSVRRSFSLSPREEEE"
     gene            4574..4867
                     /locus_tag="RHX21_004169"
     CDS             4574..4867
                     /locus_tag="RHX21_004169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012885319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="HDV1989279.1"
                     /translation="MILFRKLKAVVPPVSACTLTTFSATPALADGFQRANTVMQKVST
                     GLHGLAAITITVAVIWIGYKTLWKGESLSQCGYIIIGGILIGGGSEIGALLMS"
     gene            4880..7618
                     /locus_tag="RHX21_004170"
     CDS             4880..7618
                     /locus_tag="RHX21_004170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB3 family type IV secretion system protein"
                     /protein_id="HDV1989280.1"
                     /translation="MAKLLKAMKRPAALWGVPMVPLLAVTGVTIIVAIWTSVALLFLL
                     PVQFLVMKSLTRNEPMRFNLIAVWLRAKGKPVANRLFGATTFMPVEHDDVDIKEFLDA
                     MKLNQCATIKKYIPYSSHIHQHVVRSPKSDLYCTWELMGTPFDCESDESLQFGTNQLH
                     GLIRSFEGMPVTFYIHNDRNTFTDNLHKDSGNPYADEVSRLYYASVGLFRRNRLFLTV
                     CYRPFVSLEKAERKRMKDSQKLKELDGALLEMLEIKSTLDTALSRYGARPLGTFTEGN
                     AVFSSQLAFYEYLLTHQWRKVRVTRTPAYDVMGAAALFFSAESGQINHANGTQYFRGL
                     EVKEFAEETATGMMDSLLYAPCDYVITQSYTCMSREEAKKAIKRTRRLLMSADDDAVS
                     QRLDLDVALDLLTSGKIAYGKHHFSIMVYSPSLESLVADTNEISNALNNIGITPVPAE
                     ISLSAAYMAQLPGNYNLRPRKGELSSQNFVELAALHNFYPGKRDKAPWGDAMALLRTP
                     SGDGYYINLHNTLADKDEFNEKNPASTCILGTNGSGKTMLMTFFEIMQQKYGREDSFS
                     PDAKTKRLTTVYLDKDRGAEMNIRALGGRYYRVISGESTGWNPFSLPATKRNINFIKQ
                     LMKILCTRNGSTISPRDERRLSDAVNAVMNDEPQYRVYGITRMLENLPEPATKEAQEN
                     GLSIRLSQWAQGGEFGWVFDNESDTFDISNCDNFGIDGTEFLDDASVCAPISFYLLYR
                     ITSLLDGRRLVIFMDEFWKWLRDPVFKDFAYNKLKTIRKLNGMLVVGTQSPAEIIKDD
                     IAPAVIEQCGTQILAANPNADRAHYVDGMKFEPEVFDVVKGLDPQARQYVVVKNQFKR
                     GDTKRFAARVTLDLSGIGRYTKVMSGDAPNLEIFESIYREGMQPHEWLDTYLAKAL"
     gene            7636..8343
                     /locus_tag="RHX21_004171"
     CDS             7636..8343
                     /locus_tag="RHX21_004171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="HDV1989281.1"
                     /translation="MKTRFRTLILACVIASPLAHAGIPVAVDADPMRDVQWAQELKRW
                     METARHYQSQIQAYKDQLATATGVRDIADFVDQAKGLKADLEKLRKPGQALNDLLLSG
                     GSSGQFDALYEKYKIFDTCNTAQSGSYANVCKQQVINKAIQLEQTDEVQNQVSQTLGE
                     INSLSNRVALAKDSKESQDLANSIQLKSVMLNTLTTQWEMSVKAAEKRENALEAERVK
                     QWNQQQLNAPTADLNNL"
     gene            8351..8593
                     /locus_tag="RHX21_004172"
     CDS             8351..8593
                     /locus_tag="RHX21_004172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="HDV1989282.1"
                     /translation="MLSKKIILISTITLCFSIVGCKEEAKTTKWYRDHPDELKLAYEK
                     CQKSGDASDNCKNANEAHYQIKQLNAPTPDLNNLEE"
     gene            8597..>9315
                     /locus_tag="RHX21_004173"
     CDS             8597..>9315
                     /locus_tag="RHX21_004173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="HDV1989283.1"
                     /translation="MSGGLFVGVEKYLIGGITDATKRLMMSYSSMMMGLAAASATIYI
                     MWRGYQTLAGKLSTPMEDTMWDIMRMAIILSFVANLGGYLDGVIDAINGIKEGFSGSD
                     NIWQLLDTLWNKAKVLGKTLHDMDNSTYVKDEGMTAQFCVWLGIFALMILAGFVSMVA
                     EVMILLLGITAPIFIFCLMYGFLRPMFNNWLQNIFAGILTVLFTALSLRIVVNYLNLV
                     LNKATKVADSSTIVELGAQVCL"
BASE COUNT         2550 a         2283 c         2167 g         2315 t
ORIGIN      
        1 agttagggtt cagtaaaacc aattcgccac aaaaaaaacc accccataca tataaattat
       61 tttataggta aaatagatta tatattctca tagctaccac aaactatact agcctgaact
      121 atatttattc ttctgcaatc aatgcataca taacacaaat atcactcagg tacactactc
      181 aaaccacgct gggatttttc ctcaagttat aatcatcacc ccgaaaatca ttcggcattt
      241 actcattaaa tagtcacccc ataggcctgt acatgtttac tcagaaatat acatcctttt
      301 ctctgtcaca aaccctctga ttaatcataa ataaatactt gtgacaccaa tctttttcct
      361 taacggaacg aattgttgtg tagaaggaga taatattatg tcaaaaaaat atcagccatt
      421 gcttataact cattatatgt caacatgggt cactataacg gaagcagttg agatcactac
      481 caaagccata aaacaaaaaa ttactcctag cgatatttat cgtcatgcct tgagtggcaa
      541 catcctacta tcggtctatt tccagtctcc tgtgatactt aagaagatac aaacttttaa
      601 tggaaaaata aaattcaggc agtttgaggg agacctactt gataaactat gcatgcttga
      661 cagggacggt tttatttatg gtcaaaattt aagactctgt acagaagcca gatatgtttg
      721 tcctgtgcaa caaattatag atacccccct gataggctat gaatatgttt tgattcagcg
      781 catactggca cgtgaactta aattcccctc cccaattgtg ggggcaagaa aaactaacca
      841 tggtattata gtaagatttt cagaggagct ttttcaaatt ttcgaaacga tgagttggaa
      901 agaacgcgta gaaaaacaaa tttccagact acctaaaaac acagcattag atgtcataaa
      961 aaaactaaca gaagtgacga ccataaaata taatcacaat gggtgttttc ctctttatac
     1021 attaccgcct gatgcctgtt ttgttattcg ccacaccgaa gtcgaaagac taattaattt
     1081 atacaaaaaa agggagagtc atcccatttc accttcccgt atgacaacac cgttatcacg
     1141 cctgttttgg ctggcctgca agcacaatga tattatcagc ccactgctga atcatcccta
     1201 taagctcctt tctatttttg aacaatgggc atcaggcgat ggcatcgggg aaaaactgga
     1261 cgctgaaaca ctgaaaaatg cgctgaagcg tggttcgcca tcttcgacat ccttatccgg
     1321 ctaataccat ccccatttgt aatggccgac aaccctaaat aagggttttg catcccttat
     1381 ttagggctca ccagctttct ctcaggcttc cactgtgttt ttttattctc cggccaccgt
     1441 ttatttcagt cacaggagga tatatgacat cttatcagtt actacgcctc agacaggttg
     1501 agcaaaaaac agggctgaag cgttcacaga tataccttta tatgaaagag ggtgcatttc
     1561 cccgttcaat aaaaataggc cctgctagtg ttgcctggct cgagtctgag attgacgagt
     1621 ggatcaacaa aaagttatct gaccgataaa gatgcaatga ggagaagatg atgaacatta
     1681 atatcccggc actcataaac ttcgatcctg caggtataaa aaaaagcacc tgcatgtata
     1741 tttcagacct gcccggtatt gtgctatatg acactatacc attcactgaa tattcagctg
     1801 aattactgag tacttattca gttaaggagt caatttcatg cttccatccc tgaatcatat
     1861 tatattaacc gttgctcttc aggcgctacg ggaaggaaat attcatcact gcgaaactat
     1921 gggattcact tacgatgaaa tgaatttgct cggttgctta tcaataaacg atcttatcac
     1981 cctcagtcag gcacctttac cgcttgtcga tattactatc cgccatgatg tcctgcaaaa
     2041 attactggca tcatcccacg aggaaaacag gcgtcaggaa caactgaaca gagctgtcag
     2101 gctggggggc tcaatcgcac tgatgaaccg ttatttcggg gttggctcca gagaaacctg
     2161 tgcacgccgc cggttactcg gtgtctccgt tccaaacggg agaacaccca ttccggatga
     2221 agaaaccgat gctgcaatct ggcatcagtg gcaaaaatat cgggtcgaaa acattgattc
     2281 cccggaggcg ctggacgcca tgatgctggt tacagaaaac ctttcatcgt gtactgcccc
     2341 ctcgctgacc gttgtctgga actgcatcac gcattgcgaa agaaagaaca cggtaaggag
     2401 aatacaacgt gccagatgaa atcgatcgcg atcaggcgtt taatgaacgg tgcctagaag
     2461 cactgattga acaaagccgg ttaagaccca caccgacacc ttccctgcag cactgtcgat
     2521 tatgcggcaa ggctattccg gaaaaacgcc gtcagacgct gccgggtgta acaacctgta
     2581 ctgactgtca gtcgatactg gagaaacgca gacgttaaat ctgtatgtgc ggaggagaat
     2641 agctccgcac attttaatat gcaccagccg gcttgttttc aggttcccgt gcctccatgt
     2701 catggatgaa taacctgctc acatctcctg ctgtggcaat ccttttttac agtcagtaca
     2761 ccagaggtca gacatgaaca aaccggcaaa caagatggaa ttcgtcagaa aactgcggta
     2821 aataaatgac ggcagcctgc tggaaaaggt tgtcgggcat atggaagaaa agctcacagg
     2881 gaatgagctt gaaatgcttt atgccgcagc agattatcgc cgcgcagaga ttgtaatgaa
     2941 ccagtacttt gataaggttc ccggtaatgt ctggaaatat gtcagataac tctgtgtttt
     3001 ttatgcaaca ggtacagacg gataccactg cggcatgaaa acgaatttca ccacccggcc
     3061 cggtaagtat cggcctaagt ggccaggaaa cgtttaacca gattaaagac cgtcccttac
     3121 aacaaaaggg actactgtat tcctgtcttt cacgccttac acattattgt cgttaccaaa
     3181 ttcagccaca gagacagcat acaaccccat ctgaaatata aagaaagtct tcctccggat
     3241 gtttaattta acctgataat aatcaacaaa tattattatc agcccgcccg tcatcattca
     3301 tgcacacaca caccgtgcca gtaatacgtt aatttcacat acttttttat cattccttcc
     3361 ggtatttatt ttcccgttaa aatttcatta cccctcctgc atcctgacca tgctctttaa
     3421 caatatggag cgggctgtca cacaaccata attcagggtg ccgctgaatg ttctcgctga
     3481 cccgttaaaa ccggaatgca ggatcggaat gtgatcgaag aaatcatctt caacaatttt
     3541 aattaaacga ggacactatg agaaagcctg tttattacgc gtatgttgcc caggaaagtc
     3601 atccggactc tcagggtgag aaaaatacct ggtggacaaa ggtcggagtc gcctttcccc
     3661 accacggtaa atccggtctg aatattgtcc tgacgcccgg tattgccgtt tccggcaaac
     3721 tggtcctgct tgagccccgg gaggaaaata atccaccaca gaatacgggc cccatcgaaa
     3781 ccgtgtcgta accaccctta attctgttcc cacggcatgc agtatcagca gaccctgcat
     3841 gtcacttgtt tactgaggtc accatgcttt ccaccacagc ctttctggcg atagccatgc
     3901 agtgcgccgc cagcattcat ccgtccacgg cattcgacgt ggcacgggtg gaatccggtt
     3961 ttaaccctta tgccatcgct gagattgtcc cgaaggccgg cccctctttc ggcgatcaac
     4021 acattatttc tcacctgcca gccagccggg gagatgcaga gcatattctc cgtcgcctgt
     4081 cagcacagga tcgccgttac tctgtcgggc tgatgcaaat caccagcacc aatttccgcc
     4141 attatggtgt gtccgccaca gagctacttg atccctgtac caatctgtcc gtcttcgaac
     4201 acattctcag agactgctac cggcgcggcg gcacgctgaa aagggcgctg agttgttatt
     4261 attccggcaa tttcagtacc gggcaacaac ctgaaacggc gttttccgga acgagctata
     4321 tccagcgaat cggttatccg ccgggatcat cccgctatgc ggtccccgga acccgtgagg
     4381 acaaatcatc agttgccgtt cccctgaaaa ccgcccctgc cagtgactca tcccgtcacc
     4441 acgtgttctg gcccggagtc gtcgtccgtg gcgtccctgc gaaactccgc caagaaaaaa
     4501 tcttcatcgc acctttctcc gcgccgtcag tgcgccggag tttctccctg tcaccccgtg
     4561 aggaggagga ataatgatac ttttccgcaa gctaaaagct gtggtccccc ccgtttcggc
     4621 ctgtacgctg acgacttttt ctgcaacccc ggcactggcc gacggatttc agcgggcaaa
     4681 tactgtcatg caaaaagtgt caaccgggct gcatggtctg gcggcaatca cgatcaccgt
     4741 ggccgtgatc tggattggct ataagaccct gtggaaaggc gagagcctgt cgcagtgcgg
     4801 ctacatcatc attggcggca ttttaattgg cggaggcagt gaaatcggcg ctctgctgat
     4861 gagctaagag gctgaacata tggcaaagct gctcaaggca atgaaacgcc cggcggcgct
     4921 gtggggggtg ccaatggtgc ccctgctggc tgtcacgggt gtaaccatca tcgttgctat
     4981 ctggacttcc gtcgctctcc tgttcttact tcctgtgcaa tttctggtga tgaagtccct
     5041 taccagaaat gaaccgatgc ggttcaatct gattgccgta tggctgagag cgaagggaaa
     5101 gccggtagca aaccgtttat ttggcgcaac aacatttatg cccgttgagc atgatgatgt
     5161 tgatatcaag gagtttctcg acgccatgaa actaaatcag tgtgccacca tcaagaagta
     5221 catcccgtac tcatcgcaca ttcatcagca tgtggttcgt tcccctaaga gcgatctgta
     5281 ctgcacctgg gaattgatgg gaacgccgtt cgactgcgag tctgacgagt cgctccagtt
     5341 cgggacgaac cagttacacg ggctaatccg ctcattcgaa ggtatgccag ttactttcta
     5401 tatccataac gaccgcaata cgtttaccga caatcttcat aaagattccg gcaacccgta
     5461 tgccgatgaa gttagccgtc tttactacgc ttctgtcggt ctgttccggc gcaaccgcct
     5521 gttcctgacg gtctgctatc gcccgtttgt cagccttgaa aaagcagaac gcaaacggat
     5581 gaaagacagc cagaaactaa aggagctgga cggtgctttg ctggaaatgc tggaaataaa
     5641 aagcacgctc gataccgcgc tgtcgcgcta tggtgcgcga cctctcggta cgtttaccga
     5701 aggaaacgcg gtgttttcgt cgcaactggc tttctatgaa tatctgctaa cgcaccagtg
     5761 gcgaaaagtg cgcgtcaccc gtaccccggc ctatgacgtg atgggggcgg cggcgttgtt
     5821 cttttcggct gaatccgggc agataaacca cgccaacggt acgcaatatt tccgggggct
     5881 ggaggttaaa gagttcgccg aagagaccgc cacggggatg atggactccc ttctttacgc
     5941 cccctgcgat tacgtgatca cgcagtccta tacatgcatg tcacgcgagg aagcgaagaa
     6001 agccattaag cgtacccgcc gccttttgat gagtgccgac gacgatgctg tttcccagcg
     6061 gctggatctg gatgtggcgc ttgacctgct gacatcgggg aaaatcgctt acggcaagca
     6121 ccatttttcc atcatggtgt attccccgtc gctggaaagc ctggttgctg atacgaatga
     6181 aatcagtaac gcgctgaaca acatagggat aacgcctgtt ccggcagaaa tatcgctttc
     6241 agcggcgtat atggcgcaac tgccaggcaa ctacaacctg aggccacgta aaggggagct
     6301 gagtagccag aactttgtgg agctggccgc gctccataat ttctatccgg gcaagcgcga
     6361 taaagccccc tggggggatg cgatggcttt actgcgcacc ccgtcaggcg atggctacta
     6421 tatcaacctg cataacacac tggcagataa ggacgaattc aacgagaaga acccggccag
     6481 tacctgcatc ctcggtacga acggttcggg taaaaccatg ttgatgacgt tctttgagat
     6541 catgcagcag aaatacgggc gcgaggatag cttctccccg gatgccaaaa ccaaacggct
     6601 gacaaccgtt tacctcgata aagaccgggg cgcagagatg aacatccggg cgctgggtgg
     6661 ccgttactat cgggttatca gtggtgagtc tacagggtgg aacccgttct cgttgccagc
     6721 aaccaaacgc aatatcaatt tcatcaagca actgatgaaa atcctttgta cccgtaacgg
     6781 ctcgacgatc tccccacgcg atgaacgccg tctgagtgat gcggtcaatg ctgtgatgaa
     6841 tgacgagccg caatatcgcg tctacggcat tacccgaatg ctggaaaatt tgcctgagcc
     6901 ggctacgaaa gaagcccagg aaaacggcct tagcattcgg ttgtcacagt gggcgcaggg
     6961 cggtgagttc ggctgggtgt ttgataacga gtctgacacg ttcgatatca gcaactgcga
     7021 taacttcggc atcgacggaa cggagttcct ggacgatgca agcgtatgtg cgccaatctc
     7081 gttttatctg ctgtaccgca ttaccagcct gcttgacggg cgacgcctgg tcattttcat
     7141 ggatgaattc tggaagtggt tacgcgaccc ggtgtttaag gactttgctt ataacaagct
     7201 gaaaaccatc cgtaagctga acgggatgct ggtcgtcggt actcaatccc cggcagagat
     7261 catcaaagat gatatcgccc cggcagtgat tgagcagtgc gggacacaga ttctggcggc
     7321 gaaccccaac gccgaccgcg cacactatgt tgacggtatg aagtttgaac cggaagtgtt
     7381 cgacgtggtg aaagggcttg acccgcaagc ccgccagtat gttgtggtga aaaatcagtt
     7441 caagcgcggc gataccaaac gttttgccgc tcgtgtcacg ctcgacctgt cgggtatcgg
     7501 cagatacacc aaagtcatga gcggcgatgc ccccaacctc gaaatattcg aatcgattta
     7561 ccgggaagga atgcagcctc atgaatggct cgatacctac ctggctaaag cgctctgacc
     7621 caaaggagat atacgatgaa aactcgcttt cgtactctta ttctggcttg cgtcattgca
     7681 agcccactgg ctcatgctgg tattcccgtc gctgttgatg ctgaccctat gcgggacgtg
     7741 cagtgggcgc aggagttaaa acgctggatg gaaacggcca gacactacca gtcacaaata
     7801 caggcatata aagaccaact ggcgacggcc actggcgttc gtgatattgc tgattttgtt
     7861 gaccaggcca aaggcctgaa agctgacctt gaaaagctgc gtaagcccgg acaggcactg
     7921 aatgacctgc ttctctccgg cggttcctcc gggcagttcg atgcgttgta cgagaagtat
     7981 aaaattttcg acacctgcaa cactgcgcaa tcggggagtt atgccaacgt atgcaagcag
     8041 caggtcatca acaaggctat ccagcttgag caaaccgacg aggttcagaa ccaggtaagc
     8101 cagaccctgg gggaaataaa cagtctctcc aacagggtag cgttagccaa agattcgaaa
     8161 gaatctcaag accttgcaaa cagtattcag ctaaaatctg tcatgctgaa cacgcttacc
     8221 acccaatggg aaatgagcgt gaaagcagca gagaagcgcg aaaatgcgct agaagcggag
     8281 cgtgttaagc agtggaatca gcagcagtta aacgcgccaa ctgctgacct taataattta
     8341 tgaggtattt atgttatcaa aaaaaattat tttaatttcg acgatcaccc tgtgcttttc
     8401 tattgttgga tgcaaagagg aagctaaaac aacaaaatgg tatagggatc accctgacga
     8461 attaaaacta gcttatgaaa agtgccaaaa gagtggtgac gcttctgata attgcaagaa
     8521 tgcaaatgaa gcccactatc aaatcaagca gctaaacgca ccaactccag acttaaataa
     8581 tttagaggag taatatatga gtggcggtct ttttgttggg gttgagaaat acctgatagg
     8641 aggaattaca gacgccacaa agagattgat gatgtcgtac tcttctatga tgatggggtt
     8701 ggcagcagcg tcagctacca tctacatcat gtggcgtgga taccagactt tggctggtaa
     8761 gctatctacg cctatggaag acacgatgtg ggacatcatg aggatggcga tcatcctgtc
     8821 cttcgtggct aatttaggcg gctacctcga tggcgttatt gatgccataa acggaataaa
     8881 ggagggtttt tctggtagtg ataatatatg gcagttatta gacaccctat ggaataaggc
     8941 taaagtgtta gggaaaacgc tacatgacat ggataattct acatatgtaa aagatgaggg
     9001 aatgactgct caattttgtg tatggcttgg aatattcgca cttatgattc tagcgggctt
     9061 tgtttcaatg gttgccgaag taatgattct actattagga ataactgcac ctattttcat
     9121 attctgcctt atgtatggtt tcctccgccc catgttcaat aactggttgc aaaatatatt
     9181 tgcaggaata ttaacagttc tatttaccgc tctctcattg agaattgtag tgaattactt
     9241 gaatctcgtt cttaataagg cgacgaaggt agcagacagt tcaacaattg ttgaacttgg
     9301 tgctcaagtc tgcct
//
LOCUS       DAPGUL010000155         9158 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.158, whole genome shotgun sequence.
ACCESSION   DAPGUL010000155 DAPGUL010000000
VERSION     DAPGUL010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9158
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.158"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..287)
                     /locus_tag="RHX21_004174"
     CDS             complement(<1..287)
                     /locus_tag="RHX21_004174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989284.1"
                     /translation="MAKIPKKIDQEIKPLDLRQFVSSAAQKPASASAVTRINLTMTDD
                     DLDTAQVFQNKYGASRAEVIRAALAALRLVSAEERRRLFDDIRKNSPKAGRP"
     gene            complement(453..1112)
                     /locus_tag="RHX21_004175"
     CDS             complement(453..1112)
                     /locus_tag="RHX21_004175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-arginine deiminase"
                     /protein_id="HDV1989285.1"
                     /translation="MGKIITVAGHKGGIGKSTVLCSLCVCVIKKGKTACFLETDSQGS
                     IKDFIEDRKTNARLSEIPYFECYTDIPAMAQKLAARFDYVFVDTPGMKSPAFVKALSC
                     AHILFTFIEPGSGIEINTLGRLVFDIKTAQAGVNPSMKAWIVLNKCSTNPSDSEASEL
                     RRQLNDDPDWLPVPRQRIYMRTAHKKAYNNGMGVHEYDDKRGNKARGEIELLLKETDI
                     L"
     gene            complement(1217..2041)
                     /locus_tag="RHX21_004176"
     CDS             complement(1217..2041)
                     /locus_tag="RHX21_004176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001487124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDV1989286.1"
                     /translation="MSDLPASIFQISRSDAWNLTISPDAARNMRDLASQIGAGMPKYL
                     IAPEVSLLLSYIDDLNIRMYFETLWNTGARLNEALALKPADFMLTPTRQYPQPVVILK
                     TLKQRLKEAERRPGRPTTRHPPLHPDPRYRKPPEPAVRLVPVLDAGYALRMREYLATW
                     KKRIKHQPVWDITSRQTPLNWINTAVARAERDGVTFSVPVTPHTFRHSYAMHLTMSGV
                     PPRVLQSLLGHRYARSTEIYTRVFSLDVLTGSGLSFTCDPQLAKQLLGYPERLNNE"
     gene            complement(2306..2515)
                     /locus_tag="RHX21_004177"
                     /pseudo
     CDS             complement(2306..2515)
                     /locus_tag="RHX21_004177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001419804.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2598..3254)
                     /locus_tag="RHX21_004178"
     CDS             complement(2598..3254)
                     /locus_tag="RHX21_004178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001478769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989287.1"
                     /translation="MMIKSKKVVVIFVALSSFLLAGCDSPKDANKQNFEKAINTRLEK
                     ECITISPLGMFDSKPYPVQIAVAQANRYTSQERADEINSRQFSALDVLVKADLLTVKN
                     TLVDDVIGFTKTGKKVPGREYALTDEGKKYLKSPERPDFCVGHYKVDEIVDFTEPGDA
                     MGMKITQVNYTFSPTSIAEWAKRDDVRAAFLGLESDLKEKQTKHITLVLKNDGWSAER
                     "
     gene            complement(3358..3822)
                     /locus_tag="RHX21_004179"
     CDS             complement(3358..3822)
                     /locus_tag="RHX21_004179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS histone family protein"
                     /protein_id="HDV1989288.1"
                     /translation="MSELTKEDEYGIISRTMMNIRSLRVFAREIDFEQLLEMQEKLNV
                     VIEERREDAEREAAERQELEAKRQQAIEYIISLGLDPESLLAPVTADTVKTRRKAKGG
                     VRKAKYRFKDENGEIREWSGNGKRPLALQKLLDEGHFMEDFLIDKLQPGQVE"
     gene            complement(3838..4044)
                     /gene="hha"
                     /locus_tag="RHX21_004180"
     CDS             complement(3838..4044)
                     /gene="hha"
                     /locus_tag="RHX21_004180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="HDV1989289.1"
                     /translation="MKTKQEWLFQLRKCTSRDTLEKVIEINRYKLPLSESEAFYSAAD
                     HRRAELVMNKLYDKVPSGVWKYVH"
     gene            complement(4041..6194)
                     /locus_tag="RHX21_004181"
     CDS             complement(4041..6194)
                     /locus_tag="RHX21_004181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HDV1989290.1"
                     /translation="MRLFIAEKPAVANDIVKALGGNFTRHDGWFESDNAIVTNCFGHI
                     IESQPPENYNPEYKAWKVETLPLRLYPVKYQPVESAAKQVKTILELIRRGDVTEIVHA
                     GDPDDEGQLLVDEVLEYAGNTKPVKRVLINDNTLPAVKKALANLKDNRDFKGLYLKAL
                     ARSVADAVYGFSMTRAYTIPAKARGYQGVLSVGRVQTPVLGLIVNRTRANQNHKSSFY
                     YTMTGVFQRGADVIRANWKPGEFAPLTDRKLLDKAWADGTAASLAGKPATVEAAATDD
                     KKTAAPLPFNLVRLQQYMNKKFKMTAQKTLDITQQLREKYKAITYNRSDCSYLSDEQF
                     SEAPQVIDALKSVFPQSLDIDSARKSKAFNSAKVTAHTAIIPTASVPDVNALSTDERN
                     VYLAIAQHYLVQFMPEKAYQEVSVAIQCGDESFYARARKTTDSGFEAFLGAETTDEGE
                     SEDNDDSAFELLCKIRTGETLTTKEVVVNEKKTTPPPLFTEASLLAALVRVADFVTDP
                     TIKKLLKDKDKDKKDEHGGIGTPATRAAILETLKKRNYITLEKGKLIPTDTGYALIDA
                     LPGIAVNPDMTALWSEKQTAIENGDLTVEEFINELYGELTGMISDVDLGEMKIEPAAP
                     AGQFQRLDSPCPSCGKHIVIRPKGYFCTGCEFKIWSEFSGKKITQAQAEKLVKSGKTD
                     LIKGFKKKSGGTYDTVLVLEDKKTGKLGFPVRAKK"
     gene            complement(6199..6771)
                     /locus_tag="RHX21_004182"
     CDS             complement(6199..6771)
                     /locus_tag="RHX21_004182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012908955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDV1989291.1"
                     /translation="MQYALVDALERKFLLDALEFGVLKDWKENPVKELPDIDESVHPF
                     HICYGGYLLNPGVSDSDISRKIKDQAGFWLAAIDDTRMDCHSIAYYDIHTLPLISCGH
                     QKIVPFAALIKADECIISKIASYSGFAVTAFLRIKEWDIATNILNREGIFAFNGCERR
                     FRVVSKDNWQHTVSEERAIRCAKRLIQCKG"
     gene            complement(6775..8037)
                     /locus_tag="RHX21_004183"
     CDS             complement(6775..8037)
                     /locus_tag="RHX21_004183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDV1989292.1"
                     /translation="MGKLTLVEQALRLHKEYYGEDNFGTVVKDCDYYPKVAEIFINRK
                     NRKIYSNLDIEPVASTVVHTGSNPVMAKAGRIKKLMFKDGSGAYRIHLGQNEVVHIIR
                     FILNSKVRMEYAVGTTKSMSMLHNLCEAGRAKLNRSLPRKGIWKLGYYDGVYYHGKAR
                     KEEIENAMRFSVHPKFDELENDFNQFFSDIDFYTRYGQSGMRKVLFTGPPGTGKTTIA
                     KALGAKYQDKYVFVYADDYFKDVCYAAAQKKIPVIIIAEEVDELYRADAGTLSFLDGA
                     DTPRNVAGTYVIFSTNYPKRIDPRIRKRPGRIDRIISVGAFRTKAAAACAKMYLPEDV
                     EIDLKELGAVLDRTTPAEIKEIINIAIGMIRGTKNELSVDVIKNARAFLKGTLDLSVQ
                     EADEDIEEREELYKKNGAQPDYLSYLED"
     gene            complement(8119..8613)
                     /locus_tag="RHX21_004184"
     CDS             complement(8119..8613)
                     /locus_tag="RHX21_004184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001215543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="HDV1989293.1"
                     /translation="MRHFLKALSFVVSLLPATLCAAEIQGKVIRVLDGDTIEVKTLPA
                     KIVVYEVPIRVRLINIDAPEKKQAFGHWSANQLKALLAGQSVTVSYTQTDRYGRIIGR
                     VFTTNGTDASRFMVQSGAAWVYERYNTDKSLPALQREAQEQKRGLWADSNPVPPWEWR
                     HKQN"
     gene            complement(8610..8918)
                     /locus_tag="RHX21_004185"
     CDS             complement(8610..8918)
                     /locus_tag="RHX21_004185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989294.1"
                     /translation="MKARSVRVAGIEIIDSVKTVAYVFTEALLFMVWFSAIVYGLYRV
                     VIVLWDDPLKPQSLMEFLNFIVELYSYVLPSLAVIAVALIAVLSICKILSAIWEGRKQ
                     "
BASE COUNT         2394 a         2144 c         1906 g         2714 t
ORIGIN      
        1 ggtcttcctg ctttcgggct gtttttcctt atatcatcaa acagcctccg acgttcttct
       61 gctgatacca gacgtaacgc tgccagtgct gctctgatta cttcagcacg gcttgcaccg
      121 tacttgttct ggaacacctg cgctgtatcc agatcatcat ctgtcatagt cagatttata
      181 cgcgttactg cggatgccga tgctggtttt tgtgcagcag aacttacaaa ctggcgtaaa
      241 tccagtggtt taatttcctg atctattttc tttgggatct ttgccataag gtatcctttt
      301 tataaggtgt gtaactatac acatcattta tggcagggaa agttccggca tccacgtact
      361 gcaaattgcc aggcttggtc agataagcca tccccgccgt atatcgcatc ggatatgggt
      421 atattatcaa atttggtgtg taataataca cattacagaa tatccgtttc ttttaacaat
      481 aactcaatct cgccacgggc tttgtttccc cgtttatcat cgtattcatg tacgcccata
      541 ccgttgttat aggctttttt atgcgcagta cgcatataga tacgctggcg gggaaccgga
      601 agccagtctg gatcatcatt gagttgtcgg cgcagttctg acgcttcact gtctgacggg
      661 ttagttgagc acttattcag gacaatccat gctttcattg acggattgac tccggcctgt
      721 gctgttttaa tgtcgaaaac cagccgtccc agtgtgttga tctcaatgcc tgatcctggc
      781 tcaatgaatg tgaaaagaat gtgagcacaa ctcagagctt taacgaacgc cggagatttc
      841 atgcctggtg tatcaacaaa cacataatca aagcgggcgg ccagcttttg tgccatagcc
      901 ggaatatccg tgtagcattc gaaatacggt atttctgaca gtctggcgtt ggttttacga
      961 tcctcgatga aatccttgat acttccctgt gagtctgttt ccaggaaaca ggctgttttc
     1021 cctttcttta tgacacatac acataaggaa caaagcacgg tgctttttcc tatgccgcct
     1081 ttgtgtcctg caactgtaat gatttttccc atcacaaaat cctcctggtt aaatagtgtg
     1141 tattaataca caatcttttg tggtgaaagt ataaccgtac aattgcgtgc tggcaatagt
     1201 ttaatggtgt gtattattac tcattattaa ggcgctcagg gtacccaaga agctgttttg
     1261 caagctgtgg atcgcaggta aaggacaggc cacttcctgt aaggacgtcc agcgaaaaaa
     1321 cgcgggtgta aatctcggtg cttcttgcat aacggtgtcc cagcagggat tgcaggacgc
     1381 gcggaggaac gccactcatt gtcaggtgca tggcgtagct gtggcggaac gtgtgaggag
     1441 tgaccggaac cgaaaatgtt acgccgtcac gctctgcccg tgccactgcg gtgtttatcc
     1501 agttcagcgg tgtctgtctc gatgttatgt cccacacagg ctgatgtttg atccgctttt
     1561 tccaggtcgc caggtattcc cgcatacgca atgcgtatcc ggcatccaga acaggaacca
     1621 gccttacagc aggctctggt ggttttctgt atcgcggatc aggatgtaat ggtggatgtc
     1681 tggtggtcgg acgtcctggt cttctttctg cttcttttag acgttgcttg agtgttttca
     1741 ggatcaccac gggttgcggg tactgccgcg tcggagtcag cataaaatcg gcaggtttca
     1801 gcgccagagc ttcgttcagt cgtgctccgg tattccagag cgtctcaaag tacatacgta
     1861 tgttcagatc atcgatgtag gagagaagca gtgagacttc cggtgctatc agatattttg
     1921 gcattcctgc gccaatctgt gatgcaagat cccgcatatt acgggctgca tcgggagaga
     1981 tggttaaatt ccaggcgtcg ctacgtgaaa tctggaaaat gctggcgggt aagtcactca
     2041 attttttaat ctccgcacct gtttttctgg acgtgccagc aattatgacc tgaagcagag
     2101 gtgcgtccga caacaaaaat tccgatcacc aaaaaaaaaa tttggacatt ttttccgata
     2161 atgcattttt gtccaggtgg atatgaacga cagggcaggg cgaaaaggaa gcggttatcc
     2221 tgaataaccc aggatatggg cacatatgcc ggaacagggc accggataaa ggaacagaat
     2281 atttgaatgt tgtaactaat gaagtctgga cagaatgacc tgtatgtcta actgcctggc
     2341 gaattaaacc ggagcgaggg taatcttgtt caaaaatact gtagcggtcg cagctgagga
     2401 tcgcgctggc cagcgtgctc gatgcgtcac cggcgagaag ctgatttgtt gttttacagt
     2461 gagttaggtt gtttgcagtg cgaaaaatat cggtgagtat ttttgataga gtcattaacg
     2521 gcggtgcgct acgtgaaatc cgtgaaaaag caggggatat acgtggggta tttttcacgt
     2581 agcaacacca ttacagccta ccgttcagca gaccatccat catttttcaa aaccagtgta
     2641 atatgttttg tttgtttctc tttcaaatca gactcaagtc ctaaaaatgc agcccgaaca
     2701 tcatcgcgtt tcgcccattc agcgatactg gtgggactga atgtgtaatt cacctgcgtg
     2761 atcttcattc ccatagcatc accaggttcg gtaaaatcaa ctatctcatc caccttataa
     2821 tgaccgacgc aaaaatcagg tcgttccgga gacttcagat atttttttcc ctcatctgtc
     2881 agagcatatt cacgacctgg cactttttta cccgtcttag taaaaccaat aacgtcatca
     2941 accagggtat tttttactgt caataaatcg gctttgacca gtacatccag cgcggaaaac
     3001 tgtcgagaat ttatttcatc tgcccgttcc tgagatgtgt atcgattagc ctgagccaca
     3061 gctatctgaa ccggataagg cttactatca aacattccca gcggactaat ggtaatgcat
     3121 tccttctcta gtcgagtatt aatagctttt tcaaagtttt gcttattagc atcttttggt
     3181 gaatcacacc ctgccagcaa gaatgaactc aaagcaacaa aaataaccac tacttttttt
     3241 gatttgatca tcattttccc tctttatcaa acgataaaat ttcttgccag cgccgctggc
     3301 tgttctgtcc cctccatttg ccgtcgcaaa cttgtttgcg acggcatcac gattatttta
     3361 ttcaacctgc ccaggttgca gtttgtcaat gaggaaatct tccatgaaat ggccctcatc
     3421 aagcagcttc tgtaaagcaa gcggacgctt gccattacca gaccattctc tgatctcgcc
     3481 attttcatcc ttaaagcggt atttagcctt tcttactccg cctttggctt tccgcctagt
     3541 tttcactgta tcagctgtta caggagcaag gagtgattcg ggatcaagac ctaaagatat
     3601 gatgtattca atggcctgct gacgtttggc ttcaagttcc tggcgttcag ccgcttcacg
     3661 ttcagcatct tcacgacgtt cttcaataac aacgttgagc ttttcctgca tttcgagcaa
     3721 ctgctcaaaa tcaatctcac gggcaaaaac acgcaatgaa cgaatattca tcatagtccg
     3781 gctgataatg ccgtattcat cttctttagt cagttcgctc ataattaatc ctcttgttta
     3841 gtggacgtac ttccagacgc cggaaggaac cttatcatac agtttattca tcaccagttc
     3901 tgcgcggcga tgatctgcgg cagaataaaa tgcctctgat tctgataaag gcagtttgta
     3961 acggttaatc tcaataactt tttcaagagt atctcttgat gtacattttc ttaactgaaa
     4021 aagccattcc tgctttgttt tcacttctta gcccttaccg gaaaacccag cttccctgtt
     4081 ttcttatcct caagaacaag aactgtatca tacgttccac cgcttttctt tttaaatccc
     4141 ttaatcaaat cggttttccc tgatttaacc agtttttctg cctgcgcctg ggtgattttc
     4201 ttaccagaaa actcactcca gattttaaat tcacatccgg tacagaaata accttttggt
     4261 ctgataacaa tatgtttacc acaggaaggg cagggagagt ccaggcgttg aaactgccct
     4321 gctggcgcag cgggttcaat cttcatctcg cccaggtcaa catcagaaat catgcctgtc
     4381 agttcaccgt acagctcatt aataaactct tcaaccgtca ggtcgccatt ttcaatggct
     4441 gtctgctttt cagaccataa tgctgtcata tcaggattaa ccgctatacc aggcagggca
     4501 tcaataagcg catatccggt atcagtagga ataagtttcc ctttttccag cgtgatatag
     4561 tttcttttct tcagtgtttc cagaatggct gcgcgggtag ctggcgtacc aatgccacca
     4621 tgttcatctt ttttgtcttt atccttatct ttcagcaatt tcttaatcgt tgggtcagtg
     4681 acaaaatccg cgacgcgaac aagcgcagca agcaaggagg cttcggtaaa taatggcggc
     4741 ggtgttgttt tcttctcatt aacgacaact tcttttgtcg tcagtgtttc tcctgtgcga
     4801 attttacaga gcagttcaaa agcggaatca tcattatctt ctgattcacc ttcgtctgtg
     4861 gtttccgcgc caagaaacgc ctcaaatccg ctgtcagttg tttttctggc acgggcatag
     4921 aacgactcat caccacactg aatggcaacc gatacttcct ggtatgcttt ttcaggcatg
     4981 aactgaacaa gatagtgttg tgcgatcgcc aggtaaacat tgcgctcatc ggtgctgagt
     5041 gcgttaacat caggcacact ggcggtcggg attattgcag tatgcgcagt cacctttgca
     5101 ctgttaaacg ctttgctttt acgtgcagaa tcaatatcca gcgactgagg aaagactgat
     5161 ttcagggcat cgataacctg cggcgcttcg ctgaattgtt catcagaaag atatgagcaa
     5221 tcagagcggt tataagtaat cgctttatat ttttcacgta attgttgcgt aatatccagt
     5281 gttttttgtg ccgtcatttt gaactttttg ttcatgtatt gctggagtct gaccaggtta
     5341 aacggcaacg gtgcagccgt ttttttatca tcagttgctg ccgcttcaac tgtagccggt
     5401 tttcctgcaa gggatgctgc cgttccgtct gcccacgctt tatcaagtaa tttacggtcg
     5461 gtcagcggag caaattcccc tggcttccag ttcgccctga taacatcagc accacgctga
     5521 aagactccgg tcatggtgta gtaaaaactg gatttatggt tctggttagc acgggtacga
     5581 ttcacaatca ggccaagaac gggagtctgg acgcgcccga cagacagaac accctgatat
     5641 cctctggctt ttgccggaat ggtgtaagca cgcgtcatgg agaagccata gacggcatca
     5701 gcaactgaac gcgccagcgc cttaaggtaa agccctttga aatcacgatt atctttaaga
     5761 tttgccagtg cctttttcac tgccggaagc gtgttgtcgt taatcagaac gcgctttacg
     5821 ggttttgtgt ttcctgcata ttccaggact tcatcaacaa gtagctgtcc ctcatcatca
     5881 ggatcgccag cgtgaacaat ttcagtcacg tctccacgtc tgataagctc gagaatcgtt
     5941 ttaacctgtt ttgctgcact ttcaacaggc tgatacttca cgggataaag acgtaaagga
     6001 agcgtttcaa ccttccaggc tttgtattca ggattatagt tttccggcgg ctgtgattcg
     6061 ataatatgac caaaacagtt agtcacaatg gcgttatcac tttcaaacca gccatcatgg
     6121 cgggtaaaat tgccaccaag tgccttaaca atatcatttg ctactgcggg tttttctgcg
     6181 ataaaaagtc tcattttgtt atcctttaca ttgaattaat cttttggcac aacggatagc
     6241 gcgttcttcc gatactgtat gttgccagtt atctttactt actactctga atctgcgctc
     6301 acagccatta aaggcaaaaa ttccctcacg gttaagtata ttagttgcaa tatcccactc
     6361 tttaattctc aaaaaggctg ttacagcaaa accagaatac gaagcaattt ttgaaatgat
     6421 gcattcatca gcttttatta acgcggcaaa aggaactatc ttttgatgac cacacgaaat
     6481 cagagggagt gtgtgaatat cataataagc tattgaatga caatccatgc gggtatcatc
     6541 aatagctgcc agccagaatc ctgcctggtc ttttattttt ctgctaatat ctgaatctga
     6601 aacaccaggg tttaataaat atccaccata acagatatgg aaggggtgaa cagattcatc
     6661 aatatcagga agttctttta ccggattttc tttccagtcc ttcagaacac caaattcaag
     6721 agcatccagc aaaaattttc gttccagcgc atcaactaat gcatattgca tgtgttaatc
     6781 ctccaggtaa cttaaatagt caggttgcgc cccgttcttt ttataaagct cttccctttc
     6841 ctctatatct tcatctgctt cctgcacgct cagatcaagg gttcctttca aaaaggcacg
     6901 agcatttttt attacatcca ctgataattc atttttggtt ccgcgaatca ttccgattgc
     6961 gatattaata atttccttga tttcagccgg agtcgttctg tccagcactg cgccaagctc
     7021 tttaaggtca atttctacat cttctggtaa gtacattttg gcgcaagcgg cagcagcttt
     7081 ggttctgaaa gcacctacag agattatcct gtcaattcga cctggacgtt tcctaatacg
     7141 tgggtcgatg cgttttggat agtttgtaga aaagatcaca tatgtacctg cgacatttcg
     7201 cggtgtatca gctccatcaa gaaaacttaa cgttccggca tcagcccgat aaagttcatc
     7261 aacctcttca gctataataa tgacgggtat tttcttctga gcagcagcgt agcaaacatc
     7321 tttaaagtaa tcatcggcat aaacaaaaac atacttatcc tgatactttg cccccaaagc
     7381 ttttgcgata gttgtcttgc ctgttccagg ggggccagta aagagcactt tacgcatacc
     7441 tgactgacca taccgggtat agaaatcaat atcagaaaag aactgattaa agtcgttttc
     7501 cagctcgtca aattttggat gaactgagaa acgcatagca ttttcaattt cctcctttct
     7561 tgccttaccg tgataataaa caccatcata gtacccaagt ttccagatac ctttacgtgg
     7621 caatgagcgg tttaatttag cgcgtcctgc ctcgcaaaga ttgtggagca ttgacatact
     7681 tttagtagtc ccaacggcgt actccatcct gactttagag ttaagaatga agcgaataat
     7741 atgaacaact tcattttgac caagatgaat cctgtatgca ccagaaccat ctttgaacat
     7801 aagtttttta attctcccag ctttagccat aacagggtta cttcccgtat gaacaacggt
     7861 tgaagcaaca ggttcgatat ccagattcga ataaatttta cggttctttc tgtttataaa
     7921 aatctctgcc actttaggat agtaatcaca atcctttacg acagttccaa aattatcttc
     7981 accgtaatat tctttgtgaa gccgtaaagc ctgctctacc agagttaatt tacccataag
     8041 cgcaccatgt atatttaaaa ccgtgacact gcctgaaatt tatttaaggt agtggagggg
     8101 ttggacaagc aacgcgcgtc agttctgttt atgtcgccat tcccacggtg gaaccggatt
     8161 actgtcagcc cataaaccac gcttttgttc ctgcgcttcc cgttgcaaag ccggtaatga
     8221 tttatctgtg ttgtaacgtt catataccca tgcagcgcca gactgaacca taaagcggct
     8281 ggcatccgtg ccgttcgtcg tgaacacacg accgataatg cgtccgtagc ggtctgtctg
     8341 cgtataagag acggtaactg attgtcctgc gagcagagct ttaagctgat ttgctgacca
     8401 gtgcccgaaa gcctgtttct tttcaggagc atcgatattt atcaatcgaa ccctgatcgg
     8461 aacttcatac acaacaattt tcgcgggtag tgttttaact tctatggtgt cgccatcgag
     8521 aacgcgaata actttcccct ggatttcagc cgcacacaat gtagctggta acagggaaac
     8581 aacaaaggaa agagccttaa gaaaatgtct cattgctttc ttccctccca tattgctgag
     8641 agtattttac aaatggataa aacggcgatt aaagccactg cgataacagc caacgaagga
     8701 agtacatagc tatacaactc aactatgaaa ttaagaaatt ccatgagcga ttgcggcttt
     8761 aaaggatcat cccataaaac gataacaaca cgataaagcc catagacaat tgccgaaaac
     8821 cagaccataa acagtaaggc ctcagtaaaa acataagcga ccgttttaac actatcgata
     8881 atttcaattc cggcaactct cacacttctt gctttcatat atacctcatg gataacggga
     8941 aactaacgcc cttcggttgt tcaaccccgc aaatcccaga ttaaaatctg gaatctgcgg
     9001 cgtttacctt tatccctgtt cagaaggatt ctggataaat tttatttcat cgatttcctc
     9061 aattgaaata cgctctggta ttgttctaaa acaccacttg agtggtgttt ctttcccctt
     9121 ctccacgcta cccaacacaa ttctggtcgg gcaattct
//
LOCUS       DAPGUL010000156         9156 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.159, whole genome shotgun sequence.
ACCESSION   DAPGUL010000156 DAPGUL010000000
VERSION     DAPGUL010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9156
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.159"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..1055
                     /locus_tag="RHX21_004186"
     CDS             <1..1055
                     /locus_tag="RHX21_004186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDV1989295.1"
                     /translation="IHKPINGSTLIQTKSNDVSIFYIFRQLSFICLTSLALFCYGKDN
                     ILDNNKKKTGILLLALIPFLVFPLLAHNLSSYNADYSLYVVDYCPDNHTATWGINYTK
                     ILVCLWAFLLFFIIMRTRLASELWPLIALLCLASLCCNLLLLTLDEYNYTIWYISRGI
                     EVSSKLFVVSFLIYNIFQELQLSSKLAVHDVLTNIYNRRYFFNSVESLLSRPVVKDFC
                     VMLVDINQFKRINAQWGHRVGDKVLVSIVDIIQQSIRPDDILARLEGEVFGLLFTELN
                     SAQAKIIAERMRKNVELLTGFSNRYDVPEQMTISIGTVFSTGDTRNISLVMTEADKAL
                     REAKSEGGNKVIIHHI"
     gene            1236..2726
                     /locus_tag="RHX21_004187"
     CDS             1236..2726
                     /locus_tag="RHX21_004187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416300.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDV1989296.1"
                     /translation="MKLHHRMLRHFIAASVIVLTSSFLIFELVASDRAMSAYLRYIVQ
                     KADSSFLYDKYQNQSIAAHVMRALAAEQSEVSPEQRRAICEAFESANNTHGLNLTAHK
                     YPGLRGTLQTASTDCDTIVEAAALLPAFDQAVEGNRHQDDYGSGLGMAEEKFHYYLDL
                     NDRYVYFYEPVNVEYFAMNNWSFLQSGSIGIDRKDIEKVFTGRTVLSSIYQDQRTKQN
                     VMSLLTPVYVAGQLKGIVLLDINKNNLRNIFYTHDRPLLWRFLNVTLTDTDSGRDIII
                     NQSEDNLFQYVSYVHDLPGGIRVSLSIDILYFITSSWKSVLFWILTALILLNMVRMHF
                     RLYQNVSRENISDAMTGLYNRKILTPELEQRLQKLVQSGSSVMFIAIDMDKLKLINDT
                     LGHQEGDLAITLLAQAIKQSIRKSDYAIRLGGDEFCIILVDSTPQIAAQLPERIEKRL
                     QHIAPQKEIGFSSGIYAMKENDTLHDAYKASDERLYVNKQNKNSRS"
     gene            2769..3272
                     /gene="yeaK"
                     /locus_tag="RHX21_004188"
     CDS             2769..3272
                     /gene="yeaK"
                     /locus_tag="RHX21_004188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mischarged aminoacyl-tRNA deacylase"
                     /protein_id="HDV1989297.1"
                     /translation="MTEMAKGSVTHQRLIALLSQEGANFRVVTHEAVGKCEAVSEIRG
                     TALGQGAKALVCKVKGNGVNQHVLAILAADQQADLSQLASHIGGLRASLASPAEVDEL
                     TGCVFGAIPPFSFHPKLKLVADPLLFERFDEIAFNAGMLDKSVILKTTDYLRIAQPEL
                     LNFRRTA"
     gene            complement(3273..3377)
                     /locus_tag="RHX21_004189"
     CDS             complement(3273..3377)
                     /locus_tag="RHX21_004189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416302.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989298.1"
                     /translation="MNDQMFVETLIITSSFFAIAVVLVLSVLLIERTG"
     gene            3547..3993
                     /locus_tag="RHX21_004190"
     CDS             3547..3993
                     /locus_tag="RHX21_004190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HDV1989299.1"
                     /translation="MFDVTLLILLGLAALGFISHNTTVAVSILVLIIVRVTPLSTFFP
                     WIEKQGLSIGIIILTIGVMAPIASGTLPPSTLIHSFLNWKSLVAIAVGVIVSWLGGRG
                     VTLMGSQPQLVAGLLVGTVLGVALFRGVPVGPLIAAGLVSLIVGKQ"
     gene            complement(3950..4771)
                     /gene="nimR"
                     /locus_tag="RHX21_004191"
     CDS             complement(3950..4771)
                     /gene="nimR"
                     /locus_tag="RHX21_004191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NimR"
                     /protein_id="HDV1989300.1"
                     /translation="MMHRLNLNGYEPDRHHEAAVAFCIHAGTDELTSPVHQHRKGQLI
                     LALHGAITCTVENALWMVPPQYAVWIPGGVEHSNQVTANAELCFLFIEPSAVTMPTTC
                     CTLKISPLCRELILTLANRTTTQRAEPMTRRLIQVLFDELPQQPQQQLHLPVSSHPKI
                     RTMVEMMAKGPVEWGSLGQWAGFFAMSERNLARLIVKETGLSFRQWRQQLQLIMALQG
                     LVKGDTVQKVAHTLGYDSTTAFITMFKKGLGQTPGRYIAGLTTVSPQSAKPDPRQ"
     gene            4868..6049
                     /gene="nimT"
                     /locus_tag="RHX21_004192"
     CDS             4868..6049
                     /gene="nimT"
                     /locus_tag="RHX21_004192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-nitroimidazole transporter"
                     /protein_id="HDV1989301.1"
                     /translation="MTCSTSLSGKNRIVLIAGILMIATTLRVTFTGAAPLLDTIRSAY
                     SLTTAQTGLLTTLPLLAFALISPLAAPVARRFGMERSLFAALLLICAGIAIRSLPSPY
                     LLFGGTAVIGGGIALGNVLLPGLIKRDFPHSVARLTGAYSLTMGAAAALGSAMVVPLA
                     LNGFGWQGALFMLMCFPLLALFLWLPQWRSQQHANLSTSRALHTRGIWRSPLAWQVTL
                     FLGINSLVYYVIIGWLPAILISRGYSEAQAGSLHGLLQLATAAPGLLIPLFLHHVKDQ
                     RGIAAFVALMCAVGAVGLCFMPAHAITWTLLFGFGSGATMILGLTFIGLRASSAHQAA
                     ALSGMAQSVGYLLAACGPPLMGKIHDANGDWSVPLMGVAILSLLMAIFGLCAGGDKEI
                     R"
     gene            6104..6451
                     /locus_tag="RHX21_004193"
     CDS             6104..6451
                     /locus_tag="RHX21_004193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310528.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HDV1989302.1"
                     /translation="MNIQCKRVYDPAEQSDGYRVLVDRLWPRGIKKTDLALDEWDKEI
                     TPSTELRKAFHGEVVDFATFREQYLAELAQHEQEGKRLADIAKKQPLTLLYAAKNTTQ
                     NHALVLADWLRSL"
     gene            complement(6473..6727)
                     /gene="yoaF"
                     /locus_tag="RHX21_004194"
     CDS             complement(6473..6727)
                     /gene="yoaF"
                     /locus_tag="RHX21_004194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing lipoprotein YoaF"
                     /protein_id="HDV1989303.1"
                     /translation="MKIISFALPCLLVLAGCSTSSQPEAPKPPQIGMANPASVYCQQK
                     GGTLIPVQTAQGVSNNCKLPGGETIDEWALWRRDHPAGEK"
     gene            6910..7935
                     /gene="dgcP"
                     /locus_tag="RHX21_004195"
     CDS             6910..7935
                     /gene="dgcP"
                     /locus_tag="RHX21_004195"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416308.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcP"
                     /protein_id="HDV1989304.1"
                     /translation="MSDQIIARVSQSLAKEQSLESLVRQLLEMLEMVTDMESTYLTKV
                     DVEARLQHIMFARNSQKMHIPENFTVSWDYSLCKRAIDENCFFSDEVPDRWGDCIAAR
                     NLGITTFLSTPIHLPDGSFYGTLCAASSEKRQWSERAEQVLQLFAGLIAQYIQKEALV
                     EQLREANAALIAQSYTDSLTGLPNRRAIFENLTTLFSLARHLNHKIMIAFIDLDNFKL
                     INDRFGHNSGDLFLIQVGERLNTLQQNGEVIGRLGGDEFLVVSLNNENADISSLRERI
                     QQQIRGEYHLGDVDLYYPGASLGIVEVDPETTDADSALHAADIAMYQEKKHKQKTPFV
                     AHPALHS"
     gene            7968..8066
                     /locus_tag="RHX21_004196"
     CDS             7968..8066
                     /locus_tag="RHX21_004196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family small membrane protein"
                     /protein_id="HDV1989305.1"
                     /translation="MRIGIIFPVVIFITAVVFLAWFFIGGYAAPGA"
     gene            8069..8143
                     /gene="yoaJ"
                     /locus_tag="RHX21_004197"
     CDS             8069..8143
                     /gene="yoaJ"
                     /locus_tag="RHX21_004197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YoaJ"
                     /protein_id="HDV1989306.1"
                     /translation="MKKTTIIMMGVAIIVVLGTELGWW"
     gene            complement(8202..8450)
                     /locus_tag="RHX21_004198"
     CDS             complement(8202..8450)
                     /locus_tag="RHX21_004198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDV1989307.1"
                     /translation="MGILSWIIFGLIAGILAKWIMPGKDGGGFFMTILLGIVGAVVGG
                     WISTLFGFGKVDGFNFGSFVVAVIGAIVVLFIYRKIKS"
     gene            complement(8678..>9156)
                     /locus_tag="RHX21_004199"
     CDS             complement(8678..>9156)
                     /locus_tag="RHX21_004199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001458895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDV1989308.1"
                     /translation="IRRDYLHKVTTTVSKNHAMIVIEDLKVSNMSKSAAGTVSQPGRN
                     VRAKSGLNRSILDQGWYEMRRQLEYKQLWRGGQVLAVPPAYTSQRYACCGHTAKENRL
                     SQSQFRCQVCGYTANADVNGARNILAAGHAVLACGEMVQSGRPLKQEPTEMIQATA"
BASE COUNT         2245 a         2222 c         2168 g         2521 t
ORIGIN      
        1 ttatccataa accaattaac ggcagtacac tgatccagac aaagtcgaat gatgtttcta
       61 ttttctatat tttccgccaa ctcagtttta tttgtttaac ctcgctggca ctcttttgtt
      121 atggaaaaga caacatcctt gacaacaata agaaaaaaac gggaatcctg ttgctggcgc
      181 tgattccttt tttagttttt ccccttctgg cacacaatct gagcagttat aacgctgact
      241 attctttgta tgtcgtcgac tactgtccgg acaaccatac tgcgacctgg ggaatcaact
      301 atacaaaaat attggtttgt ctgtgggcat ttttactgtt ctttattatc atgcgtacac
      361 gattagccag cgaactatgg ccgttaatag cattattatg tctggcatcg ctatgctgca
      421 acttacttct actgactctg gatgagtata attacaccat ctggtatatc agtcgcggga
      481 ttgaagtttc cagtaaactg tttgttgtgt cttttctgat ttataacatt tttcaggaac
      541 tgcaactctc cagcaaactg gcagttcatg atgtgctgac caatatttat aatcggcgct
      601 actttttcaa cagcgtagag tcattattgt cgcgacctgt tgttaaggac ttctgtgtca
      661 tgctggttga tattaatcag ttcaaacgca tcaatgccca atggggacat cgtgtgggtg
      721 ataaagtgct ggtttcaatt gtcgatatta tccagcaaag catccgccct gatgatattt
      781 tagcgcgact ggagggtgag gtgtttggct tgctatttac cgaactcaat agtgcccagg
      841 caaaaatcat tgcggaacgt atgcgtaaaa atgtcgaact cctgaccggc tttagtaaca
      901 gatatgatgt tcctgaacaa atgaccatca gtattggcac ggttttttca acgggtgaca
      961 cgcgtaatat ctcgcttgtc atgacggaag cagataaagc cttacgcgaa gcgaaaagcg
     1021 aggggggcaa caaagtgatt attcatcata tttaagtgca aaaatattca gagccatgct
     1081 ttttgcgtgg cttttgcata caatttatta ctattacccc taaatttccc ctccccagcg
     1141 gcgcagagat gagtataatt agcgcccctg tgccaggccg caatcgaact ttatctggtt
     1201 ttctcgtttc actaaccgaa ggagtgccat ttatcatgaa attgcaccat agaatgctcc
     1261 ggcattttat cgccgcaagt gtcattgtgc tgacatcttc cttccttatt tttgaacttg
     1321 tcgccagcga cagagcaatg agtgcctatc tgcgctatat cgtgcagaaa gcagactcct
     1381 cctttcttta tgataagtat cagaatcaga gtattgccgc gcatgtgatg cgcgctctcg
     1441 ctgctgagca gtcggaagtg tcgccagaac agcggcgcgc catctgcgag gcttttgagt
     1501 ctgccaataa tacccatggc ttaaacctga ctgcccataa atacccgggc ttacgcggca
     1561 cactacaaac cgcatccact gactgcgaca caattgtgga agctgcagca ctattacccg
     1621 cttttgatca ggcagtggaa ggcaaccgcc accaggatga ttacggttca ggtcttggga
     1681 tggccgaaga gaaatttcac tattatctcg atctcaatga ccgctatgtc tatttttatg
     1741 agccggttaa tgttgaatac tttgcgatga ataactggtc cttcctgcag tcaggaagta
     1801 ttggcatcga tcgcaaagat attgaaaagg tatttaccgg gcgtaccgta ttgtcgagca
     1861 tttaccagga tcagcgtact aaacagaacg tgatgagttt gctgacgccg gtatatgtcg
     1921 cagggcagct aaaagggatt gtgctgctgg atattaacaa aaacaatttg cggaatatct
     1981 tttacactca tgaccgccct ctcctctggc gttttctcaa tgtcacgcta accgataccg
     2041 attcggggcg cgacattatc atcaaccaga gcgaagataa tctgttccag tatgtcagtt
     2101 acgtccatga cttaccgggc ggcattcgtg tctcgttatc cattgatatt ctttacttta
     2161 tcacgtcttc gtggaaaagc gttctgttct ggattttgac ggcgttaatt ttgctgaata
     2221 tggtgcggat gcacttccgc ttataccaaa atgtgtcgcg agaaaatatt agtgatgcga
     2281 tgactggact gtataatcgc aaaattttaa cccctgaact ggagcagcgg ttgcagaaac
     2341 tggtgcaatc cggttcttcg gtgatgttta ttgcaattga catggacaag ttaaagctaa
     2401 taaatgacac cctcggtcat caggaagggg atttagcgat tacgttgtta gctcaggcga
     2461 ttaaacaatc gattcgtaaa agtgattatg ccatccgact cggtggcgat gaattctgca
     2521 tcattcttgt cgattcgacg ccgcaaattg cagcacaact gcctgaacgt atcgaaaaac
     2581 gtctgcaaca tatcgcgccg cagaaagaga tcggcttctc ttccggtatt tacgcgatga
     2641 aagaaaacga tacgttacat gatgcgtata aagcttccga tgagcgttta tatgtcaata
     2701 agcagaacaa aaacagccgt tcatgataac cttctgtggt tgtttgcttg taatctcagg
     2761 agcgtgaaat gactgaaatg gctaaaggaa gcgtgacgca tcagcggtta atcgctttat
     2821 tatcacaaga aggtgctaac ttccgcgtcg ttacccatga agcggtaggt aaatgtgaag
     2881 cggtgtcaga aattcgtggc accgctttag gccagggagc taaggcactg gtatgtaaag
     2941 tcaaaggcaa tggcgtaaat caacatgttc tggcgatcct cgctgccgat caacaggccg
     3001 atctgagcca actcgccagc catataggcg gattacgcgc ttcgttggcc agcccggcgg
     3061 aagtcgatga actcacaggc tgtgtcttcg gcgcgatccc ccctttcagc ttccatccaa
     3121 aactcaaact ggttgccgac cctctactct tcgaacgatt tgatgaaatc gccttcaatg
     3181 cagggatgct ggataaatcc gttattttga aaaccacgga ttatttgcgc attgcgcaac
     3241 cagaactgct caatttccgc cgcactgcgt aactagcctg tccgttcaat aagcagaacg
     3301 gacaaaacca gcacaacagc aatggcaaaa aacgatgacg tgataatcag tgtctcgacg
     3361 aacatttgat cgttcatagc atgcccccgg gagatagctg ttttcacgtt attgttagcg
     3421 tgcacaaatg gcagtttgat gacagttcgc ctgatttttt atgcaaaaaa cgtaaagatt
     3481 ttctacttcc ttcctgcagc aagcgtaaag taagcaggct tattattttt tggcaaggaa
     3541 accacgatgt ttgatgtcac tttgctgatc ctgctcgggt tagctgcgct gggctttatc
     3601 agtcataaca ccactgtcgc cgtttcaatt ctggtgttga tcattgtccg cgtcacaccg
     3661 ttaagcacct ttttcccgtg gattgaaaaa caggggctaa gtatcgggat aatcattctg
     3721 acgattggcg ttatggcccc catcgccagc gggacgctac cgccctcaac cttgattcac
     3781 tcgtttctga actggaaatc gctggtggca attgcagtag gcgttattgt ctcctggctg
     3841 ggtgggcgcg gcgtgacctt aatgggcagc cagccgcaac tggtcgccgg gctgctggta
     3901 ggcactgttt taggcgtggc gctgtttcgc ggcgtaccgg tcggcccgct tattgccgcg
     3961 ggtctggttt cgctgattgt ggggaaacag tagttaatcc cgcaatatat cggcctggcg
     4021 tttgccccag gcctttctta aacatagtaa taaaggccgt tgttgaatca taccccagcg
     4081 tatgagcaac tttctgtaca gtatcgcctt tcactaatcc ctgaagtgcc ataatcagct
     4141 gtaactgctg acgccactgg cgaaaactca accccgtctc ttttactatc agtcgggcaa
     4201 gattgcgttc actcatcgca aaaaagccag cccattgccc taatgacccc cactcgacgg
     4261 gccctttcgc catcatctcc accatcgtgc ggattttagg atgagaagaa acgggcaggt
     4321 gcagctgttg ttgtggctgc tgagggagtt catcaaacag gacctgaatt aatctgcggg
     4381 tcatcggctc agcacgctga gtcgtcgtcc tgtttgccag ggttaaaatc aattcccggc
     4441 ataagggcga tattttcaat gtgcaacatg ttgtcggcat tgtcactgcg ctgggttcga
     4501 taaacagaaa acagagttca gcgttagctg tcacttgatt gctatgttcc accccgcccg
     4561 gtatccaaac cgcatattgc ggcggcacca tccacaaagc attttccacc gtacaggtaa
     4621 ttgcaccatg taatgctagt atcagctgtc ctttgcggtg ctgatgtaca ggactggtta
     4681 actcatccgt tccggcgtga atacaaaatg cgaccgcggc ttcatggtgt cggtcgggtt
     4741 catagccatt gagattcaac ctgtgcatca ttttgtccga atttagcgat aatttgtcat
     4801 tttagcttga ttcaacataa caataaaaac ggtaaggtac agcctcgttt gtaacaatga
     4861 gaagcatatg acctgttcaa cttcattaag cggcaaaaac aggattgtcc ttatcgctgg
     4921 cattctgatg attgccacaa cattacgcgt cacctttacc ggcgcagcgc cgttactgga
     4981 tacgattcgt tccgcttact cgctgacgac agcgcaaacc ggcttattaa ccaccctgcc
     5041 attattggcc tttgcgctaa tctcaccttt ggctgccccg gtggcgcgac gttttggtat
     5101 ggaacgtagc ctgtttgccg cgttactttt gatctgtgca ggtatcgcaa ttcgttctct
     5161 cccttcgcct tacttattat ttggcggtac agcggtcatt ggcggtggga ttgcattagg
     5221 caatgtctta ctgccaggat taattaaacg cgatttccct cattccgtcg ccagacttac
     5281 cggcgcatat tccctgacaa tgggagctgc agcggcactg ggatcggcta tggtcgtgcc
     5341 gctggctttg aacggttttg gctggcaagg cgcgttgttc atgctgatgt gttttcctct
     5401 gctggctctt tttttatggc tgccacagtg gcgaagccaa caacatgcaa atttgagtac
     5461 ctcgcgcgcc ttacatactc ggggtatctg gcgttcgccg cttgcctggc aggtcacatt
     5521 gtttcttggg atcaactcac tggtctatta cgtgattatt ggctggcttc cggcgatcct
     5581 catcagtcgc ggctatagcg aagcacaggc gggttcactg catggtttgc tgcaactagc
     5641 cacagcagct cccggtttgc tgatccctct tttcttacat catgtgaaag atcagcgtgg
     5701 tattgcagcg ttcgttgcct tgatgtgcgc agtgggcgct gttgggctct gctttatgcc
     5761 agcgcacgcg atcacctgga ctctgctttt cggttttggt tccggcgcaa caatgatact
     5821 ggggttgacg ttcattggtc ttcgggcaag ttctgcgcat caggcggcgg cactctcggg
     5881 gatggcacaa tccgtcgggt atttgctggc agcctgtggg ccgccgctga tgggtaaaat
     5941 acacgatgct aacggtgact ggtccgtacc actgatgggt gttgccatac tttcactact
     6001 gatggcgatt ttcggacttt gcgccggggg agacaaagaa attcgctaat atccggtgct
     6061 atagtgacgt gacaaatcat gcgtgaaagg gagaacaaac acgatgaata ttcagtgcaa
     6121 acgcgtttat gatccggctg aacagagcga tggttatcgc gtactggtcg accgcctctg
     6181 gccgcgcggt atcaaaaaaa ccgatttagc ccttgatgag tgggataaag aaatcacgcc
     6241 gtcaacggaa ctgcgcaaag cctttcacgg cgaagtcgtc gattttgcaa cctttcgcga
     6301 gcaatatctt gcagaactgg cgcaacacga gcaagaagga aagcggctgg cggacatcgc
     6361 caaaaaacag ccgctgaccc tgctctacgc agcaaaaaac accacgcaga accatgcgct
     6421 ggtgctggcc gactggctac gtagcttgtg attttagtac agcatccggc ggttattttt
     6481 caccagccgg atggtcccgt cgccacaatg cccattcatc aatcgtttca ccgcccggta
     6541 atttgcaatt gttgctgacc ccttgcgctg tctgcactgg aatgagcgtc ccgcccttct
     6601 gctggcaata gaccgacgcc ggatttgcca taccaatctg cggcggttta ggtgcttctg
     6661 gctgagaaga ggttgaacaa ccagccagga ccagcaagca aggcaaagca aaactgataa
     6721 ttttcattta ttgatctcac acatttatct acgcttagag tatcgcggta tcgttttgtt
     6781 ttgcagcact atttttatta cattcactca aaacatatta cgtcttgttt catctttgtt
     6841 gatgatgttt tatcatgcct gcaaagatta aataatcagc atttacccgc cgtatcctgg
     6901 agttgtttcg tgtcagatca gattatcgcc cgcgtctcgc aatcccttgc caaagaacag
     6961 tcactagaaa gtctggtccg acagcttctg gagatgctgg aaatggtcac tgatatggaa
     7021 tcaacctacc tgaccaaagt ggatgtcgaa gcgcgcctgc agcatattat gtttgcccgt
     7081 aacagccaga aaatgcacat cccggagaat tttaccgtct cgtgggatta ctcgttatgc
     7141 aaacgcgcca ttgatgaaaa ctgctttttc agcgatgaag tccctgaccg ttggggcgac
     7201 tgtattgcgg cacgcaatct tggcatcacc acatttctga gcacgccaat tcacttaccg
     7261 gatggatcat tctatggcac gctttgcgcc gccagcagtg agaagcgcca gtggagtgaa
     7321 cgcgcggaac aggttttaca gttattcgct ggactgattg cacaatatat tcaaaaagag
     7381 gcgctggttg aacagctgcg cgaagccaat gctgcgctga ttgcgcaatc gtataccgac
     7441 tcgttaaccg ggctaccgaa tcggcgggcg atttttgaaa atctgacgac gctgttttct
     7501 ctcgcccggc atcttaacca taagataatg atcgcgttta tcgatctgga taacttcaaa
     7561 ttaatcaatg atcgttttgg tcataatagt ggcgatctgt ttctcattca ggttggcgag
     7621 cgccttaata cgctccagca aaatggcgaa gttattggtc gtctcggcgg tgatgagttt
     7681 ttggttgttt cactaaacaa cgagaatgcg gatatttcgt cgctgcgaga acgtattcaa
     7741 cagcaaatac gtggagaata tcacttaggt gatgttgatt tgtattatcc cggtgccagt
     7801 cttggcatag tagaagtcga tcctgaaaca accgatgcag acagtgccct gcatgctgcc
     7861 gatattgcga tgtatcagga gaaaaaacac aaacagaaaa caccttttgt cgcgcatcca
     7921 gcgctacatt cctgaggcgt attcacatcc ttttgattgg tgataacatg cgaatcggta
     7981 ttatttttcc ggttgtaatc tttattacag cggtcgtatt tttagcatgg ttttttattg
     8041 gcggctatgc tgccccggga gcataaagat gaaaaaaaca acgattatta tgatgggtgt
     8101 ggcgattatt gtcgttctcg gcactgagct gggatggtgg taacgtcacc tctaaaaaat
     8161 agcaaaggct gcctgtgtgc agcctttgtg caatttaagc gttaactttt aatcttcctg
     8221 tagataaata gcacgacaat cgcaccaata acggcaacca cgaagctgcc aaaattgaag
     8281 ccatcgactt taccaaagcc aaacagtgtg ctgatccatc cgccgactac ggcaccgact
     8341 atccccagca gaatagtcat aaagaatcca ccaccatctt tacctggcat gatccacttc
     8401 gccagaatac cggcaataag cccaaaaata atccatgaca gaatgcccat tgtttcctca
     8461 cttatctgtt ttgcattagc gggttagtcg ctgataaaaa gcatagcaca acatcgggag
     8521 ggcaagattt gtgacgagca tcacggagga tttttttgcg gatggcacag aaattgcgcc
     8581 atcaacgatc agtgataatt accaaccaca aacatcatgt tcgttttccg tatcttgaca
     8641 tcctccaccc cctgaatgac gaggatccct gctacgttca ggctgtcgcc tgaatcattt
     8701 cggtgggttc ctgcttcaac gggcggcctg actgcaccat ctctccacag gcaagaacgg
     8761 cgtgccccgc cgctaaaatg ttacgagcgc cgtttacatc ggcgttcgct gtatatccac
     8821 atacctggca tctgaattga ctttgtgaca ggcgattttc tttcgctgta tgaccacagc
     8881 acgcgtaacg ctggcttgtg tacgctggcg gaacagcaag cacctgaccg ccacgccaga
     8941 gctgcttgta ctcaagctgg cggcgcattt cataccagcc ctgatccagt atcgaacggt
     9001 ttaaacctga ttttgcccgg acattgcgcc ccggctggct gaccgtaccc gctgctgact
     9061 ttgacatgtt gctgaccttc aaatcctcaa tgactatcat tgcgtggttt ttgctgacgg
     9121 tcgttgtgac tttgtgaagg tagtccctgc ggatat
//
LOCUS       DAPGUL010000157         9025 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.160, whole genome shotgun sequence.
ACCESSION   DAPGUL010000157 DAPGUL010000000
VERSION     DAPGUL010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9025
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.160"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..424)
                     /locus_tag="RHX21_004200"
     CDS             complement(<1..424)
                     /locus_tag="RHX21_004200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HDV1989309.1"
                     /translation="MNPSDAIEAIEKPLSSLPYSLSRHILEHLRKLTSHEPVPGIMGK
                     SGAGKSSLCNALFQGEVTPVSDVHAGPREVQRFRLNGHGHSMVITDLPGVGESRDRDA
                     EYEALYRDILLELDLVLWLIKADDRALSVDEYFWRHILH"
     gene            complement(508..1659)
                     /locus_tag="RHX21_004201"
     CDS             complement(508..1659)
                     /locus_tag="RHX21_004201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000514103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989310.1"
                     /translation="MGKELDDICTSCPYIDAVKRHKQQLGAIEEYTQWLKKEPRASYF
                     FLFQLYTRIHNTFFSQKQQLPFTPGGTHCPEPDVTLRDLTLSPGYHSDYAPQPIPEMD
                     SSAVVPPTNENTSPPEDTPDNTPAGGNTGQAEKTRNAGLTPIPEKRSGMPPEHLRFAT
                     GFPSQPKIAGPREKPMRTVHPDKIYREIIWFCSSYLLKSGPEATRTIINSVFSEWASI
                     NNDYPSPFSWVDSRDSEQCDWLWNAMQVRCVGTPLNPLTPEQKYWFACATFDNWEGWN
                     EQQVQFLLESNPRRNRAKFTQVSFQAPRIQHKAILLDELKSAREQQKRRDERADGSVP
                     LKLSGKIHKQLESIARSRGVLPKKLLNEMIEQAYHDLVATRQNSQIDSR"
     gene            complement(2790..2945)
                     /locus_tag="RHX21_004202"
                     /pseudo
     CDS             complement(2790..2945)
                     /locus_tag="RHX21_004202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544830.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            complement(2989..3148)
                     /locus_tag="RHX21_004203"
                     /pseudo
     CDS             complement(2989..3148)
                     /locus_tag="RHX21_004203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000952428.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
     gene            3227..3610
                     /locus_tag="RHX21_004204"
     CDS             3227..3610
                     /locus_tag="RHX21_004204"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HDV1989311.1"
                     /translation="MRAKERLPRKHYSPEFKMELVRLALEEEGSIAALARKHDVNDNL
                     LFKWIRLWQREGRVCRPRKNSSSLPALIPVQLQAGSSLPTFELPSCSPPATCHIKCRG
                     GEITLTHPSAELMSTVLRELMRGPV"
     gene            3607..3954
                     /gene="tnpB"
                     /locus_tag="RHX21_004205"
     CDS             3607..3954
                     /gene="tnpB"
                     /locus_tag="RHX21_004205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004966400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HDV1989312.1"
                     /translation="MINLPAGTKIWLVAGITDMRNGFNGLAAKVQTALKDDPMSGHVF
                     IFRGRSGSQVKLLWSTGDGLCLLTKRLERGRFAWPSARDGKVFLTPAQLAMLMEGIDW
                     RQPKRLLTSLTML"
     gene            4004..5605
                     /locus_tag="RHX21_004206"
     CDS             4004..5605
                     /locus_tag="RHX21_004206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001000399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HDV1989313.1"
                     /translation="MNDTSSDDILLLKQRLAEQEALIHALQEKLSNREREIDHLQAQL
                     DKLRRMNFGSRSEKVSRRIAQMEADLNLLQQESDTLHCRVDDPAVQRPLRQTRTRKPF
                     PESLPRDEKRLLPTEPCCPECGGSLSYLGEDAAEQLELMRSAFRVIRTVREKHACRRC
                     DRIVQAPAPSRPIERGIAGPGLLARVLTSKYAEHIPLYRQSEIYARQGVVLSRSVLSG
                     WVDACCRLLAPLDEALQHYVLTDGKLHADDMPVPVLLPGNKKTKTGRLWTYVRDDRNA
                     GSALAPAVWFAYSPDRKGIHPQTHLAGFSGVLQADAYAGFNELYRDGHIKEAACWAHA
                     RRKIHDVHVRTPSALTEEALKRIGELYAIESELRGKRAEERQAVRHQKVLPLLASLEG
                     WLREKQKTLSRHSELAKAFGYALNQWPALTRYAEDGWVEVDNNIAENSLRLVSLGRKN
                     WLFFGSDHGGERGASLYSLIGTCKLNGVDPERYLHHVLDVIADWPVNRVGALLPWRVT
                     LPDQLHFVNTVLTARLPFSARHMSM"
     gene            complement(6494..7096)
                     /locus_tag="RHX21_004207"
     CDS             complement(6494..7096)
                     /locus_tag="RHX21_004207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989314.1"
                     /translation="MKQQYQTRYELLHENYQKWLTGFTRHAVSWGVCHPNIYYFHNLT
                     PGWVSFNGEKPEIAIVPQSLHRLIYGPDKRSSPSLDDDLVVNLCTSEHLLVHHPMLEG
                     ILLSECERLKQHSLANKLISLFRQFGGTELRLKLVWLCWLDLMTGNSLDDWTKNLKHK
                     SEKDLEQWIIARQGQSEPLTNLMDQYVLMAYRTSVDAAHS"
     gene            complement(7190..7396)
                     /locus_tag="RHX21_004208"
     CDS             complement(7190..7396)
                     /locus_tag="RHX21_004208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020234041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family phage regulatory protein"
                     /protein_id="HDV1989315.1"
                     /translation="MATPVSLMDDQMVDMAFITQLTGLTDKWFDKLIKDGGFPAPIKM
                     GRSSRWLKSEVEAWLQARIAQSRP"
     gene            8843..8929
                     /locus_tag="RHX21_004209"
                     /pseudo
     CDS             8843..8929
                     /locus_tag="RHX21_004209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001375328.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus Gp2 family protein"
     gene            8921..>9025
                     /locus_tag="RHX21_004210"
     CDS             8921..>9025
                     /locus_tag="RHX21_004210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus Gp2 family protein"
                     /protein_id="HDV1989316.1"
                     /translation="MTYKYNPFWQQRIRETVRHALNVHPRLTALRVDLR"
BASE COUNT         2073 a         2311 c         2400 g         2241 t
ORIGIN      
        1 ggtgcaggat gtgtcgccag aaatactcat ccacagacag ggcacggtca tcggctttaa
       61 tcagccacag taccaggtcc agttcgagca gaatgtcacg gtacagggct tcatactctg
      121 catccctgtc ccggctctcg cccaccccgg gcaggtcagt gataaccatg ctgtgaccat
      181 ggccattcag acggaagcgc tgcacttccc gggggccggc gtgaacatca ctgaccgggg
      241 tgacctcccc ctgaaacagc gcattacaga gtgaggattt accggccccg cttttaccca
      301 taatgccagg cacgggttcg tgactggtga gtttgcgcag atgttccagg atgtgacggg
      361 aaagtgagta aggcagggag gagagcggtt tttcaattgc ctcaatggca tcagacggat
      421 tcatacatgt attcccggtg aaaaaagaca aaaccccgcg caccggaaag gtggcggggg
      481 attcacggaa ataatatctg tctgaaatta tctggaatcg atttggctgt tctgcctggt
      541 tgccaccaaa tcatggtacg cctgctcaat catttcattc agcagttttt ttgggaggac
      601 accacgactt cgggcaatac tttcaagctg tttgtggatt tttccggaca gtttcagagg
      661 gacggaacca tcagcacgtt catcacgcct tttttgttgc tcccgggcac ttttcagctc
      721 atcaagaaga atcgctttat gctgaatcct gggggcctgg aaggagacct gcgtaaactt
      781 cgctctgttc cgtctgggat tactttccag taaaaactgt acctgttgct cattccagcc
      841 ctcccagtta tcaaacgtgg cgcaggcaaa ccagtatttc tgctccgggg taaggggatt
      901 cagcggggtt cccacacacc ggacctgcat ggcgttccat aaccagtcac actgttcact
      961 gtccctgctg tccacccacg aaaaggggga ggggtaatca ttgtttatgc tggcccattc
     1021 agagaatact gagttgataa tcgtcctcgt agcctctggt ccggatttca gcaggtaact
     1081 ggagcagaac catataattt cacggtagat tttatccgga tgcacggtgc gcatcggctt
     1141 ttctctggga ccggcaatct tcggttgcga tggaaacccc gtggcaaacc gcagatgttc
     1201 cgggggcatt cctgaacgtt tttcaggaat gggtgtgagt cctgcgtttc tggtcttttc
     1261 cgcttgtccg gtattgcctc cggccggagt gttgtcggga gtatcttccg gaggcgaggt
     1321 gttttcatta gttgggggaa caacagcaga actgtccatc tccggaatgg gttgaggggc
     1381 ataatcactg tggtagccag gggaaagcgt taagtcccga agggtgacat caggttccgg
     1441 gcagtgagtg ccaccgggag tgaacgggag ttgttgcttt tgggagaaaa atgtattgtg
     1501 aatgcgggta tacagctgga acagaaaaaa ataagatgcc cgtggttctt tttttaacca
     1561 ctgtgtatat tcctctatgg caccgagctg ttgtttgtgc cgttttacag catcgatata
     1621 cggacagctg gtgcagatat catccagttc ctttcccaca atacacctca cctgcttttc
     1681 tcacatttgc agattttaaa aaagcaaaca aaaacctccg tacatgatgt acagaacaat
     1741 ctaccaggta gtggcgtcag aaaacctccg ggccgcctgc actttccgga atgcgccggt
     1801 tatgaaaaac cggaaattca gtctctgttg taagatgtac cctctgatac tacgttttct
     1861 ctgtgtattt aactcactgt atttattgtc tttttaagct tgactgatat tctccggtca
     1921 tagtgtgccg gatatacatc ccgtaaactt ctcattttta tataaaaata cctgcactct
     1981 cttcagcgca tctgtctcct ttaagtaaaa aatgttttca cgtattgctg taaattcatt
     2041 ttaaatcagt atattacctt gatattgctg tctcctggtt tgatgcgtaa tcgttctgcc
     2101 tttctggatg attctggtgc ttccgggtgc attctcctct gcacatgcaa cagttcgtca
     2161 tcgccacgct cccaaaaagc atataaaaac gaatcgaatt tgatattttt ttcaatcgtt
     2221 tttcatagga atttcgtagg gtattctccg ctataacctc catatttgct gtctttttct
     2281 tcataaatcg tatgcaatat agcctgtctg tcaagacctc ttctctgctg ttgaggagac
     2341 gatctcattt ttggtctttt ccgggagaga ggctgtcaga tgagcgagcc ggatatactg
     2401 tcagaggtac accccgtagc agacctgtgc tcccatttcc gcgatccgga accaacaaca
     2461 ccctacggtt aataccattt gaagcgttag gtactgcagg aagttccccc ctgcgcggac
     2521 atcggttcct gccgacatct cacaatacgg ccagactgtc atgcagtaac acccgcatgc
     2581 ggtctgcggt tttaagcgca ctctcccgtt ttcagtgcac cgataatgcg tcatagtaag
     2641 tctgggggaa gttacggaat gcctgttaag tggtgccgtg ggtggagaca gcttactttt
     2701 ctacagcaac tgcagtcatt caggatgatc aggagatatt ctgtcaatgt cacgatcctg
     2761 ccattttcgt acccgctaag atacttccgt tactgatgct gtccgctttt caccatttca
     2821 tcctcactga caggcgttgc gttttgggtc atcaccacag ctttacgttt ctcttttaac
     2881 cggtaacgct ctcctttgat attcagcgtg gttgagtgat gcagcagtca atccaggagc
     2941 gctgttgtcc ggcaaccacc atatcaactt cttcccgggt gtggcggaga ggtggtatcc
     3001 tggctgagtt tcgaagcgaa ccgttctttt tgacgggcgc attttacgtc cgggctgaat
     3061 gtagtaacgc ggcatggaac gtcggcccgt ataccattgc cttaatctcc gcaaagataa
     3121 cctcgtcatt ccggacattc tctgtaagcg tcgtctgagt accgtctggt cccgaatcca
     3181 ggatcctgta acttaagcac ccacttattt tgcaggtgga cacctcatgc gcgctaaaga
     3241 aagacttccc cggaaacact attcccctga attcaaaatg gaactggtca ggctggctct
     3301 tgaagaagaa ggcagtattg ccgcactggc ccggaaacat gacgtcaatg ataacctgct
     3361 ctttaaatgg ataaggctct ggcagcgtga agggcgggtc tgtcggcccc gaaaaaactc
     3421 atcgtcgctt cctgccctga tacccgtgca gcttcaggcg ggctcttctc tcccaacctt
     3481 cgaactacca tcctgctctc ctcccgctac ctgccacata aaatgtcggg gaggagaaat
     3541 aacactgact catccctctg ctgaactcat gagcactgtc ctgcgcgaac tgatgcgggg
     3601 gcctgtatga taaatcttcc cgcaggcaca aaaatctggc tggttgccgg tatcaccgat
     3661 atgcgcaacg gcttcaatgg cctcgccgca aaggtgcaga ccgcgctgaa agatgacccg
     3721 atgtccggcc acgtcttcat cttccgggga cgcagcggca gtcaggtaaa actgctctgg
     3781 tccaccggcg atggtctgtg cctgctgaca aagcgactag aacgtggtcg cttcgcctgg
     3841 ccctcagccc gcgatggcaa agtgttcctg acgccggcgc aactggcgat gctgatggaa
     3901 ggtatcgact ggcgacagcc aaagcggtta ctgacatccc tgaccatgtt gtagcgctct
     3961 ttatcctggt tgtcgcagaa taagcctggt aaaatacagg cttatgaacg acacctcttc
     4021 tgacgacatc cttctgctga aacagcgcct ggccgaacag gaagcgttga tccacgccct
     4081 gcaggaaaag ctgagcaacc gggaacgcga aatagaccat ctgcaggcgc aactggataa
     4141 gctgcgccgg atgaacttcg gcagtcgttc cgaaaaggta tcccgccgta tcgcgcaaat
     4201 ggaagctgac ctgaacctgc tgcagcagga aagcgatacg ctgcactgcc gggtggatga
     4261 cccggcagtg cagcgcccgc tgcgtcagac ccgcacccgc aaaccgttcc ctgagtcact
     4321 cccacgggat gagaagcggc tgctgccgac tgagccgtgt tgcccggagt gcggtggttc
     4381 gctgagttac ctgggtgagg atgccgccga acagctggag ctgatgcgca gcgccttccg
     4441 ggttatccgg acagtccgtg aaaagcatgc ctgccgtcgg tgcgatcgca tcgttcaggc
     4501 cccggctcct tcgcgcccca tcgaacgggg gatcgccgga ccggggctgc tggcccgagt
     4561 gctgacctca aagtatgcag agcacatacc gctgtatcgc cagtcggaga tctatgcccg
     4621 ccagggtgta gtgttgagtc gttctgtact gtcgggctgg gtggatgcgt gttgtcgtct
     4681 gctggcaccg ctggatgaag cccttcagca ctatgtcctg accgacggca aactccatgc
     4741 tgacgatatg cctgtcccgg tgctgttgcc gggcaataag aagacgaaga ccgggcgctt
     4801 atggacgtac gttcgagacg accgcaacgc cggatcagcg ctggcccccg cagtgtggtt
     4861 cgcttacagc ccggacagaa aaggtatcca ccctcagacc catcttgcag gcttcagtgg
     4921 cgtactgcag gctgatgcct acgccgggtt caacgagctc taccgcgacg gccatataaa
     4981 ggaagccgcg tgctgggccc atgcccgccg aaaaatccac gatgttcacg tccgtacccc
     5041 gtcagccctg acggaggagg cgctgaaacg gatcggcgag ctgtatgcca tcgagtcgga
     5101 gctcagaggt aaaagagcag aggaacggca ggcagtccgg caccaaaaag tgctgccgct
     5161 gctggcgtca ctggaggggt ggctgcggga gaaacagaaa accctctcaa ggcactcaga
     5221 actggcgaag gcgttcgggt atgcgctgaa ccagtggccg gcgctgaccc gctatgcaga
     5281 agatggctgg gtggaggtgg ataataacat tgccgaaaac tccctacgac tggtcagtct
     5341 ggggagaaaa aactggctgt tcttcggctc ggatcatggt ggtgagcgcg gtgcgtcact
     5401 gtacagtctt atcgggacgt gcaaattaaa cggcgtggat ccggaacgct atctgcatca
     5461 tgtacttgat gtcatcgccg actggcctgt gaaccgggtg ggtgctctgc tcccgtggcg
     5521 ggttactctg cctgaccagc ttcacttcgt caatacggtt ctcactgcac gcttaccatt
     5581 ctctgccagg catatgtcga tgtaatccat aaacgatttc agcttacccc ttttgtggcc
     5641 agtctttctg gctggcggtt caggggatgt tttctggtta tcgtgtacca caaagcaggg
     5701 atattgcccc gatagtcaca tttcagattg atcgcggtct gaagatgtgg cactgaggta
     5761 acgtgctggt gtcactggta ttgctgaagt tatggttttt cggggtcagg tgagcctgtt
     5821 gtgtgtatgc tttttgttca ggtcagaggg ggactgtgtg gacagcggct tttgtctccg
     5881 ggcattcacg cctgaacgat gaatgcgatt ttcagcaata tttgtctttg tgacactctc
     5941 tggttgagaa gctaatgcgc gcccctgttt ccacagagaa tgaggcttgc catcagccga
     6001 aacatcagta ttccacgcta tacagacggc gcctgaccat gtgctgatgc aggtaaaatg
     6061 tttcactaca actgttcggg ttgctatgca acgaaacagc gattctcacg atctttaact
     6121 gcaacgtttt tccgcctgaa agctgactgc ctcctgctga ggtgggaggc tatgattcag
     6181 tgcgtttata gtctccgggg tatgcatgta ccggagcata ccatttctgg tggataacaa
     6241 gccggcacat tcagactgca gtgaagatgg aggcacctgg ttgtgaagaa cgtttctgcc
     6301 cgtggctgct tcgcatcatc aatggtattc atacccgctc agaaatgacc gggtgctgaa
     6361 gccctccgtt atcgcgcagt ataatgacgt atatgatctg tggaagagtg agcggcgtgc
     6421 ctgatgtacg ccgctattac tgtattttac cacagggctg gttttctgct gccagccctg
     6481 tggttctcag acatcaactg tgagcggcat caaccgatgt acggtatgcc ataagcacgt
     6541 actgatccat cagatttgtc agtggttcac tctgaccctg acgtgcaatg atccattgct
     6601 ccagatcttt ttctgatttg tgtttcaggt ttttcgtcca gtcgtcaagg ctgtttccgg
     6661 tcattaagtc aagccagcag agccagacca gtttgagacg taactccgtg ccgccaaact
     6721 gacggaagag gctgatcagt ttgtttgcca gagaatgttg cttcaggcgc tcacattcag
     6781 acagcaggat cccttccagc atcggatgat gaaccagcag gtgttcgctg gtgcataaat
     6841 tcaccaccag atcatcatcc agggacgggg agctccgttt gtccggacca taaatcagcc
     6901 ggtgcagact ctggggaacg atggcaatct ccggtttttc gccattgaat gacacccacc
     6961 cgggcgtcag attatggaaa tagtagatat tcggatgaca cacgccccat gatacggcgt
     7021 gccgggtgaa gccggtcagc catttctggt agttttcatg gagcagctcg taacgggtct
     7081 gatactgttg tttcattttc atattcctca cgggggataa caggcagcag agcgccgccg
     7141 gcaggccgga gattgcgtct gctgtgggcg aagggttagt ggttaaaaat tacggacggg
     7201 actgtgcaat acgcgcctgc agccaggctt ccacttcact tttcagccag cgggagctgc
     7261 gccccatttt gatgggcgca ggaaagcccc catctttgat gagtttgtca aaccacttat
     7321 cggttaggcc ggtcagttga gtgataaacg ccatgtcgac catctggtca tccatcagcg
     7381 aaactggggt agccatgaga atgttcctcc ggatgttgtt aaaccagccg gtgtggtcat
     7441 gaaaacagcg cgccaccttc accggcataa caaccgggga gaaacgtaaa aaataatcgg
     7501 gaatgtgacc gccaggagat aaacggggag gttgcggtgg ctgagccgta ccggtatacc
     7561 gggtggttgt tgcgaaaaga tgcttccgca cgcacgcgcg ataaagaggg gatagttttc
     7621 gtgaggacag ggagagaagc aggcgttctg ataattgcag agttgttttc ggaggtggtt
     7681 acagtgagtc agcccgttcc tggcgagcag gagactgata tcaccgatgg gataaggttg
     7741 tctgattggt attataaata taagaagtca tcagagagta acgtaaagga tttgccagaa
     7801 taacctaaga gagtaaatct ctccggtaac agagcgctgt gaagcattct gtatcagagt
     7861 gcagatacat gaacgctgat gcgtaaaatc agcagtgaca cgccagctcc ccctgtgccc
     7921 attcctgtat aagacatgaa ctgagtgtat taatgcttct gccctgagac tgagccggtg
     7981 agtgaggggc tgagaaatcc ctcttgacac agctctaacc agaaatactt ccccggttgt
     8041 tgcggtgcgt ccggatcccc gataacggaa cactaaggct gtattgcggg acaccgggta
     8101 agtagcagcc cgtaaggcgt tctgtcaacg ccagaaaaaa tgatttccca cacgcgttat
     8161 agactcactc ctgtggacct ggaagcccgt aactctgcgg ttgcccactg actgacggaa
     8221 ctgaccgcaa attttacgag tgcgtgctgg gcttcagtct ggtcacctga gcgttcggta
     8281 acggaggcgc gggcggtaat aggctgattt tcaggtatta ccggcttaca gcgtgtggtt
     8341 gatattgagg ggctgtgagt ttcgcgtatt tgtcagaaac ccagacgagt tttcctgtat
     8401 gggacgaaat aaggcagcgg caatacctgg aaaaatttaa tatggtatga aggagaacct
     8461 gtcggttacg cttaatatac ccggtacact gtcagctcag gggatacatg aaccgttatc
     8521 tcaccagcta cacagtatat acacactgac gctgacagta gtcagcagga ccacaataat
     8581 cagtgccagc agtatggtaa cgatacggtc tgtattccgg taatagccga aggggtcgac
     8641 agaaccacaa tacgggcaac acactgtatt atgagtaatc gcgtttccac agtccctgca
     8701 cttctttttg cgtatcacca tcactccctc ctcacagcct tacccgtaac cggtttttta
     8761 cattaaaaaa acaacgctga aaattcaacc gtcagtccgg agacgaccgt tcgggttatc
     8821 acagagtgcc tgagacagtg tcctgccgga ggtcacttca gggactctgc gcatttttta
     8881 cgacgtggct attccgtatg aaccatacgg agatttaacc atgacctaca aatacaaccc
     8941 cttctggcag caacgtattc gtgagacggt gcggcacgca ctgaatgttc atccccgcct
     9001 gacggcattg cgggttgacc tgcgt
//
LOCUS       DAPGUL010000158         8933 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.161, whole genome shotgun sequence.
ACCESSION   DAPGUL010000158 DAPGUL010000000
VERSION     DAPGUL010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8933
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.161"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            36..308
                     /locus_tag="RHX21_004211"
     CDS             36..308
                     /locus_tag="RHX21_004211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3811 domain-containing protein"
                     /protein_id="HDV1989317.1"
                     /translation="MALPRITQKEMTEREQRELKTLLDRARIAHGRVLTNSETNSIKK
                     EYIDKLMVEREAEAKKARQLKKKQAYKPDPEASFSWSANTSTRGRR"
     gene            complement(309..1181)
                     /gene="rluF"
                     /locus_tag="RHX21_004212"
     CDS             complement(309..1181)
                     /gene="rluF"
                     /locus_tag="RHX21_004212"
                     /EC_number="5.4.99.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2604) synthase RluF"
                     /protein_id="HDV1989318.1"
                     /translation="MLPDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRATIGD
                     QVKPGDVVKVNGQLIEPREAEDLVLIALNKPVGIVSTTEDGERDNIVDFVNHSKRVFP
                     IGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITDEFIRGMGAGVPIL
                     GTVTKKCKVKKEAPFVFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPL
                     GEWRDLTDDELIDLFKLIENSSSEAKPKVKAKPKTAGIKRPVVKMEKTAEKGGRPASN
                     GKRFTSPGRKKKGR"
     gene            1393..2082
                     /gene="pepE"
                     /locus_tag="RHX21_004213"
     CDS             1393..2082
                     /gene="pepE"
                     /locus_tag="RHX21_004213"
                     /EC_number="3.4.13.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepE"
                     /protein_id="HDV1989319.1"
                     /translation="MELLLLSNSTLPGKAWLEHALPLIAEQLQGRRSAVFIPFAGVTQ
                     TWDDYTAKTAAVLAPLGVSVTGIHSVVDPVAAIENAEIVIVGGGNTFQLLKQCRERGL
                     LAPITDVVKRGALYIGWSAGANLACPTIRTTNDMPIVDPQGFDALNLFPLQINPHFTN
                     ALPEGHKGETREQRIRELLVVAPELTIIGLPEGNWITVSKGHATLGGPNTTYVFKAGE
                     EAVPLEAGHRF"
     gene            complement(2173..3804)
                     /locus_tag="RHX21_004214"
     CDS             complement(2173..3804)
                     /locus_tag="RHX21_004214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HDV1989320.1"
                     /translation="MLTLLHLLSAVALLVWGTHIVRTGVMRVFGARLRTVLSRSVEKK
                     PLAFCAGIGVTALVQSSNATTMLVTSFVAQDLVALAPALVIVLGADVGTALMARILTF
                     DLSWLSPLLIFIGVIFFLGRKQSRAGQLGRVGIGLGLILLALELIVQAVTPITQANGV
                     QVIFASLTGDILLDALIGAMFAIISYSSLAAVLLTATLTAAGIISFPVALCLVIGANL
                     GSGLLAMLNNSAANAAARRVALGSLLFKLVGSLIILPFVHLLAETMGKLSLPKAELVI
                     YFHVFYNLVRCLVMLPFVDPMARFCKTIIRDEPELDTQLRPKHLDVSALDTPTLALAN
                     AARETLRIGDAMEQMMEGLNKVMHGEPRQEKELRKLADDINVLYTAIKLYLARMPKEE
                     LAEEESRRWAEIIEMSLNLEQASDIVERMGSEIADKSLAARRAFSLDGLKELDALYEQ
                     LLSNLKLAMSVFFSGDVTSARRLRRSKHRFRILNRRYSHAHVDRLHQQNVQSIETSSL
                     HLGLLGDMQRLNSLFCSVAYSVLEQPDEDEGRDEY"
     gene            complement(4024..7707)
                     /gene="metH"
                     /locus_tag="RHX21_004215"
     CDS             complement(4024..7707)
                     /gene="metH"
                     /locus_tag="RHX21_004215"
                     /EC_number="2.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HDV1989321.1"
                     /translation="MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLNEADFRGERFAD
                     WPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYQMESLSAE
                     INFAAAKLARACADEWTARTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDGLV
                     AAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKTEFEALGVELPIMISGTITDA
                     SGRTLSGQTTEAFYNSLRHAEALTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAG
                     LPNAFGEYDLDADTMAKQIREWAQAGFLNIVGGCCGTTPQHIAAMSRAVEGLAPRKLP
                     EIPVACRLSGLEPLNIGEDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVE
                     NGAQIIDINMDEGMLDAEAAMVRFLNLIAGEPDIARVPIMIDSSKWDVIEKGLKCIQG
                     KGIVNSISMKEGVDAFIHHAKLLRRYGAAVVVMAFDEQGQADTRARKIEICRRAYKIL
                     TEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNVS
                     FSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAELRDAVEDVILNRR
                     DDGTERLLELAEKYRGSKTDDTANAQQAEWRSWEVNKRLEYSLVKGITEFIEQDTEEA
                     RQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASK
                     EQGKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAKEVNA
                     DLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVY
                     VQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPRTPPVTLEAARDNDF
                     AFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVE
                     AQRLFKDANDMLDKLSAEKTLNPRGVVGLFPANRVGDDIEIYRDETRTHVINVSHHLR
                     QQTEKTGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMV
                     KALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYPACPEHT
                     EKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQVEDYA
                     RRKGMSVTEVERWLAPNLGYDAD"
     gene            7907..8731
                     /gene="iclR"
                     /locus_tag="RHX21_004216"
     CDS             7907..8731
                     /gene="iclR"
                     /locus_tag="RHX21_004216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418442.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate bypass operon transcriptional
                     repressor IclR"
                     /protein_id="HDV1989322.1"
                     /translation="MVAPIPAKRGRKPAVATAPATGQVQSLTRGLKLLEWIAESNGSV
                     ALTELAQQAGLPNSTTHRLLTTMQQQGFVRQVGELGHWAIGAHAFMVGSSFLQSRNLL
                     AIVHPILRNLMEESGETVNMAVLDQSDHEAIIIDQVQCTHLMRMSAPIGGKLPMHASG
                     AGKAFLAQLSEEQVTKLLHRKGLHAYTHATLVSPVHLKEDLAQTRKRGYSFDDEEHAL
                     GLRCLAACIFDEHREPFAAISISGPISRITDDRVTEFGAMVIKAAKEVTLAYGGMR"
BASE COUNT         2061 a         2464 c         2296 g         2112 t
ORIGIN      
        1 tacactgaac tctctggctc actgagggca ccatcatggc actcccccgt attacccaaa
       61 aagagatgac tgaacgcgag cagcgtgaac ttaaaacact gctggatcgg gcgcggattg
      121 cgcatggtcg cgtactgacc aactccgaaa ccaacagcat taagaaagag tacatcgata
      181 aattaatggt cgagcgtgag gctgaagcga aaaaagcccg ccagttgaag aaaaagcagg
      241 cttataaacc ggatcctgaa gcgtcattta gctggtcagc aaatacgtcg acgcgcggca
      301 ggcgctgatt agcgcccctt ctttttacgc cccggagagg taaaacgctt accgttggac
      361 gccgggcgac cgcctttttc cgccgttttt tccatcttaa cgactggacg tttgatgccc
      421 gctgttttcg gtttggcctt cactttaggt tttgcctcgg aagaggaatt ttcgatgagc
      481 ttaaagaggt cgattaactc atcatcagtt aaatcgcgcc actcacccag cggaatgccg
      541 cttaaactga cgttcataat gcgcgtacgt tccagctttt tcacttcata gccgaaatgc
      601 tcgcacatgc gccggatctg acggttcagc ccctgcacca gggtaatgcg gaagacaaac
      661 ggcgcttctt ttttgacttt acacttttta gtcactgtcc cgaggattgg cacccccgcc
      721 cccataccac gaataaattc atcggtaatc ggtttatcga ccgtaaccag atactctttc
      781 tcatgatcgt tacccgcacg gaggatctta ttcaccagat cgccgtgatt ggtgaggaaa
      841 atcagcccct gggagtcttt atccaggcgg ccaatcggga acacgcgttt gctgtggtta
      901 acgaaatcga caatgttatc gcgctcgcca tcttcggtgg tgctgacaat accgacgggc
      961 ttgttcaggg cgataagtac caaatcttcg gcttcccgag gctcaatcaa ctgaccgttt
     1021 actttcacaa cgtcgccggg tttcacctga tcgccaatgg tggctcgctt gccattaagg
     1081 aacacattgc cttgctcgat atagcgatcc gcttcgcggc gtgagcaaat tccgctttcg
     1141 ctgatgtatt tatttaaacg gactgatgag tcgggcagca taaattctcc tgtaaaaaac
     1201 ggaatatacc gtacctttgg gttgataaaa aatagtcatg agcgaactat ttgttatttc
     1261 cattggcttg aattcgttac ctgctcaaat cactttccag aagcaatgtg cgacatcgtg
     1321 agccatgtca gtaagtggtt aaattcgcag tggtagcatg cctcccgtga tttcttacta
     1381 accggagaag taatggaact gcttttattg agtaactcga cgctgccggg taaagcctgg
     1441 ctggaacatg cactgccgct aattgctgaa cagttgcagg gtcgccgctc agcggtgttt
     1501 atccctttcg ctggcgtaac gcagacctgg gatgattaca cagcgaaaac ggctgcggtt
     1561 ctcgctccgc tgggtgtttc tgtcaccggt attcatagcg ttgtcgatcc cgttgccgcg
     1621 attgaaaatg ctgagatcgt gattgtcggc ggcgggaata ctttccagtt gctgaaacag
     1681 tgccgcgagc gcgggctgct ggcaccaatt actgacgtgg ttaaacgtgg cgctctgtat
     1741 attggctgga gcgcaggcgc taaccttgct tgcccaacca ttcgtaccac caacgatatg
     1801 ccgattgtcg atccgcaagg tttcgatgcg ctaaatctgt tcccgttgca aatcaacccg
     1861 cacttcacca acgcgctgcc ggaaggccat aaaggtgaaa cccgtgagca gcgtattcgc
     1921 gaactgctgg tcgtcgcgcc agaactgacg attattggtc taccggaagg taactggatc
     1981 acagtgagta aaggtcacgc tacgctgggt ggcccgaaca ccacttatgt gtttaaggct
     2041 ggtgaagaag cggtgccgct agaagctggt caccgttttt aagtgaattg ccggatgcat
     2101 gatccggcat cttgttcata gtgcctgatg cgacgcttga cgcgtcttat caggcctaca
     2161 ggattcacaa tattaatact cgtcccgtcc ttcatcttca tccggctgtt ccagcacact
     2221 gtaagccacc gaacaaaaca gcgagttcag gcgctgcata tctcccagta agcctaaatg
     2281 tagcgaactg gtttcaatgc tctgcacgtt ttgctgatgc aggcgatcga cgtgggcgtg
     2341 ggaatagcgg cgattaagaa tgcgaaagcg atgcttacta cggcgcaaac gacgagcgct
     2401 ggtgacatcg ccagagaaga acaccgacat tgccagcttt aaattactga gcaattgctc
     2461 atagagcgca tccagttcct tcaacccatc aagcgaaaat gcccgccgtg ctgccagtga
     2521 tttgtcggca atttcactcc ccatgcgctc gacgatatcg gaggcctgtt caaggttgag
     2581 cgacatttcg atgatctctg cccagcggcg cgactcttcc tccgccagct cttcttttgg
     2641 catccgcgcc agatacagct taatggcggt gtagagaacg ttgatatcat ctgccagctt
     2701 acgcagctct ttctcctgcc gtggctcacc gtgcatcact ttattcaacc cttccatcat
     2761 ctgttccatg gcgtcgccaa tgcgcagggt ttcgcgcgcg gcgttcgcca gagcaagcgt
     2821 gggcgtatcc agcgcgctga catccagatg tttaggccgt agctgggtat ccagttccgg
     2881 ttcatcgcga ataatcgttt tgcaaaaccg tgccatcggg tcaacaaatg gcagcatgac
     2941 caggcaacgt acaaggttgt agaagacgtg gaaatagatc accagttccg cttttggcaa
     3001 tgacagcttc cccattgtct ctgccagcaa atggacaaac ggcaggataa tcaggctacc
     3061 caccagctta aacagcagac tacccagcgc gacacggcgg gctgcggcat tggcggcact
     3121 gttgttgagc atcgccagca gaccggaacc gaggttagca ccaatcacca gacagagcgc
     3181 cacggggaag gagataatgc ctgcggcggt cagagtcgcg gtcagcagta cagcagcaag
     3241 gctggagtag ctgataatgg cgaacatcgc gccaatcagc gcatccagca gaatatcgcc
     3301 ggtcagcgag gcaaagatca cctgaacgcc gtttgcctgg gtgatcggcg ttacggcctg
     3361 cacaatcaac tccagcgcta gcaaaatcag cccaagacca ataccgacgc ggcccagttg
     3421 cccggcgcgt gactgtttgc gtccgaggaa aaaaatcacg ccgataaaaa taagtaacgg
     3481 tgacagccag gataagtcga aggtgagaat acgcgccatt agcgccgtcc cgacatctgc
     3541 acccagcaca atgaccagag ccggtgcgag ggctaccaga tcctgagcga caaacgaggt
     3601 caccagcatg gtggtggcat tactgctctg taccagtgcg gtaacgccga tccccgcgca
     3661 aaaggcgagc ggcttttttt cgacgctccg gctaaggaca gtacgcaaac gcgcgccgaa
     3721 gacgcgcatt acgccggttc gaacaatatg agtcccccag accagcaggg cgacggcaga
     3781 aagcaggtga agcagcgtta acacgagttc aggttctcct tatcgttata tgttcctgaa
     3841 gcaattgaat gaccaaagga ccggaaacac gttgactggc atctttactg tgccttttga
     3901 cattcgtttt tccggctaag attattccag cctgtttcca gtataagtgt ttcatattaa
     3961 taaagagaca gggcactcat tgagcgccct gtttgttgta aggaaaagtg acagatttgt
     4021 gaatcagtcc gcgtcatacc ccagattcgg tgccagccag cgctcaactt cggtaacgct
     4081 cataccttta cggcgggcat agtcttcaac ctgatcgcgc tgaatttgcg ctaccgcgta
     4141 atacttgctg tccgggtggc tgaagtacca acccgaaacc gatgcaccag gccacatggc
     4201 gaaagattct gtgagtttca tgccagtgtg tttttccact tccagcagct cccagatggt
     4261 ggctttttcc gtatgttccg ggcaggccgg atagcccggt gccggacgga tgccctggta
     4321 gttttcgcgg atcagttctt cgttgctgag gttctcgttc ggcgcatagc cccagtagac
     4381 tttacgcaca cgctcatgga gatactccgc aaaggcttcg gctaaacggt cggcaagcgc
     4441 tttcaccatg attttgttgt aatcatcgtg ctgcgcttca aaggcatcag ccagtgcgtc
     4501 ctcttccagc ccgccagtca cggcaaatgc gccgatgtaa tctgctttac cagaaagctt
     4561 cggcgcaacg aagtcagcga gacagtagtt agcgaatccc gttttttcgg tctgttgacg
     4621 cagatggtgg ctgacgttga tcacatgagt gcgcgtttcg tcacggtaga tttcaatgtc
     4681 atcgcccaca cggtttgccg ggaacaggcc caccacgcca cgcggattca gcgttttctc
     4741 ggcgcttaat ttatccagca tgtcgttggc gtctttaaac agccgctgcg cctcaacgcc
     4801 taccacttca tcttccagaa tgcgcggata cttcccggcc agcgaccagg tcataaagaa
     4861 cggtgtccag tcgatgtaat tgcgcagcgt ttcgatgctg gcttcgactt cctgcacgcc
     4921 gagacggtgc gccaccggcg gcgtgtaagc ctgccagtca aaagcgaaat cgttatcgcg
     4981 cgccgcttcc agcgtgaccg gtggtgtgcg cggcttcttg cgcccgtgct gaatacgtac
     5041 ggtttcgtac tccttgcggg tacgagcgac aaaatcatca cgctgggtat cggaaagcag
     5101 cgccgccacc acaccaacgg tacgcgatgc gttctgcaca tacaccgtcg ggccgctgta
     5161 gttctgctcg attttcaccg ccgtgtgcgc ttttgaggtg gtcgcgccgc caatcaatag
     5221 cggaatagtg aagccctgac gctccatctc tttcgccacg ttaaccatct cgtccagcga
     5281 cggcgtgata agccccgaaa gtccaatcag atcagcattc acttctttag cggtacggag
     5341 aattttttcc gcaggcacca taacgccgag atcgacaatt tcgtagttgt tacattgcag
     5401 caccacacca acgatatttt taccgatgtc gtggacgtcg cccttcacgg tggcgatcac
     5461 catcttgccg ttggttttac cctgctcttt gctggcttca ataaacggtt cgagatacgc
     5521 cactgcctgt ttcatgacgc gcgccgattt gaccacctgt ggcaggaaca ttttcccttc
     5581 gccaaacaga tcgccgacca cgttcatacc gtccatcagc gggccttcaa tcacttcaat
     5641 cgggcgcgta gcctgctggc gggcttcttc ggtatcctgc tcgataaact cggtaatgcc
     5701 tttaaccagc gagtattcca gacgtttatt cacttcccac gagcgccact ccgcctgctg
     5761 ggcgttagcg gtgtcgtcgg ttttgctgcc gcgatatttc tcggcaagct ccagtaaacg
     5821 ctcagtgcca tcgtcgcgac ggttaagaat cacatcttcc accgcgtcgc gcagttcagc
     5881 gggtaggtcg tcgtaaatcg ccagttgccc ggcgttgacg atccccatat ccatgccatt
     5941 gcgaatagcg tagtagagga acaccgcgtg aatggcttcg cgcaccggat cgttgccacg
     6001 gaatgagaaa gaaacgttag atacaccgcc ggaaatcagc gcgtgcggca gttcgcgttt
     6061 gatatcttca cacgcgccga taaagtcctg cgcgtagttg ttgtgctctt caatgccggt
     6121 tgcgaccgcg aagatgttcg ggtcgaagat gatatcttct ggcgggaagc caacctcttc
     6181 ggtgaggatt ttgtacgccc gacggcaaat ctcgattttc cgtgcgcggg tatcggcctg
     6241 tccctgttcg tcaaaggcca ttaccaccac tgccgcaccg taacgacgca agagcttcgc
     6301 gtgatggata aaggcgtcga cgccctcttt catcgagata gagttaacaa tgcctttgcc
     6361 ctggatacac ttcagacctt tttcaatgac atcccatttt gaggagtcga tcataatcgg
     6421 cacgcgagcg atatccggtt caccggcaat cagattgaga aaacgcacca tcgccgcttc
     6481 ggcgtcgagc atcccttcat ccatgttgat atcgataatc tgcgcaccgt tttccacctg
     6541 ctggcgggcc acatccagtg cctcgctgta tttctcttct ttgatcaggc gcttgaactt
     6601 agcggaaccg gtgacgttgg tgcgttcacc cacgttcaca aacaggctat cttcgccaat
     6661 gttcagcggc tccaggccgg acaaacggca ggctacgggg atttccggca gtttgcgcgg
     6721 cgctaatcct tctactgcac gactcatcgc tgcaatatgt tgtggcgtgg tgccacagca
     6781 gccgccgacg atattgagaa aacccgcttg cgcccattca cgtatctgtt ttgccatcgt
     6841 gtcggcgtcg agatcgtact caccaaaggc gttgggtagc ccggcgttcg ggtgcgcggt
     6901 gacgtagcat tccgcaatcc gtgacagctc ctgcacgtac tggcgcagtt catctggccc
     6961 cagcgcacag ttcaggccaa aggtcagagc ttcggcgtgg cgcaatgagt tgtaaaatgc
     7021 ttcggtggtc tgcccggaga gcgtgcgccc ggaggcgtcg gtgatggtgc cggagatcat
     7081 aatcggcagc tcaacgccca gcgcttcaaa ctccgttttc accgcaaaga ccgccgcttt
     7141 ggcgttaagg gtgtcgaaaa cggtttcaat caggatcaga tccgcaccac cttccaccag
     7201 cgctttggtg gactctcgat aagccgccac cagcccgtca aaagtgatat tacgaaatgc
     7261 cggatcgttg acgtccggag aaatagacgc cgtgcggttg gttgggccga gaacaccggc
     7321 aacgtagcgc ggtttctccg gggtgcgcgc ggtccactca tcagcacagg cgcgcgccag
     7381 tttcgccgcc gcaaagttga tttccgccga cagggattcc atctggtaat ccgccatcgc
     7441 aatggtcgtg gagttgaagg tgttggtttc gatgatatcc gcgcccgctt caaagtaggc
     7501 gttgtggata gcggcgatca cttccggttt actgagtacc agcaggtcgt tgttgccttt
     7561 gaggtcgcat ggccagtcgg caaagcgttc accacgaaaa tcggcttcgt tcagtcgata
     7621 gctctggatc atggtgccca taccgccgtc cagcaccaga atacgttcat ttaactgcgc
     7681 acgcagttgt tccactttgc tgctcacact tgctcccgac acgctcaacc cagatttaat
     7741 aaaaattcaa caaaccatac tggcataaac gcatctgtgg taaaagcgac caccacgcaa
     7801 catgagattt gttcaacatt aactcatcgg atcagttcag caactattgc attagctaac
     7861 aataaaaatg aaaatgattt ccacgataca gaaaaaggag actgtcatgg tcgcacccat
     7921 tcccgcgaaa cgcggcagaa aacccgccgt tgccaccgca ccagcgactg gacaggttca
     7981 gtctttaacg cgtggcctga aattactgga gtggattgcc gaatccaatg gcagtgtggc
     8041 actcacggaa ctggcgcaac aagccgggtt acccaattcc acgacccacc gcctgctaac
     8101 cacgatgcaa cagcagggtt tcgtgcgtca ggttggcgaa ctgggacact gggcaatcgg
     8161 cgcacatgcc tttatggtcg gcagcagctt tctccagagc cgtaatttgt tagcaattgt
     8221 tcaccctatc ctgcgcaatc taatggaaga gtctggcgaa acggtcaata tggcggtgct
     8281 tgatcaaagc gatcacgaag cgattattat cgaccaggta cagtgtaccc acctgatgcg
     8341 aatgtccgcg cctatcggcg gtaaattgcc gatgcacgct tccggtgcgg gtaaagcctt
     8401 tttagcccaa ctgagcgaag aacaggtgac gaagctgctg caccgcaaag ggttacatgc
     8461 ctatacccac gcaacgctgg tgtctcctgt gcatttaaaa gaagatctcg cccaaacgcg
     8521 caaacggggt tattcatttg acgatgagga acatgcgctg gggctacgtt gccttgcagc
     8581 gtgtattttc gatgagcacc gcgaaccgtt tgccgcaatt tcaatttccg gaccgatttc
     8641 acgtattacc gatgaccgcg tgaccgagtt tggcgcaatg gtgattaaag cggcgaagga
     8701 agtgacgctg gcgtacggtg gaatgcgctg acttttttct ggcgggcaga ggcaatattc
     8761 tgcccgtcat atctgagtgg caatagaata agggtgtctg ttaatcgcat tgacgccaaa
     8821 ataacttatt gtcatacact tcgcacactt ttattaactc agcattattt ttaaacatca
     8881 aaccacttaa ttattaacaa aatcgcaaga tctcattacg ccgaaacttt tac
//
LOCUS       DAPGUL010000159         8909 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.162, whole genome shotgun sequence.
ACCESSION   DAPGUL010000159 DAPGUL010000000
VERSION     DAPGUL010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8909
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.162"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(206..1306)
                     /gene="chaA"
                     /locus_tag="RHX21_004217"
     CDS             complement(206..1306)
                     /gene="chaA"
                     /locus_tag="RHX21_004217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-potassium/proton antiporter ChaA"
                     /protein_id="HDV1989323.1"
                     /translation="MSNAQEAVKTRHKETSLIFPVLALVVLFLWGSSQTLPVVIAINL
                     LALIGILSSAFSVVRHADVLAHRLGEPYGSLILSLSVVILEVSLISALMATGDAAPTL
                     MRDTLYSIIMIVTGGLVGFSLLLGGRKFATQYMNLFGIKQYLIALFPLAIIVLVFPMA
                     LPAANFSTGQALLVALISAAMYGVFLLIQTKTHQSLFVYEHEDDSDDDDPHHGKPSAH
                     SSVWHAIWLIIHLIAVIAVTKMNASPLETLLDSMNAPVAFTGFLVALLILSPEGLGAL
                     KAVLNNQVQRAMNLFFGSVLATISLTVPVVTLIAFMTGNELQFALGAPEMVVMVASLV
                     LCHISFSTGRTNVLNGAAHLALFAAYLMTIFA"
     gene            1576..1806
                     /gene="chaB"
                     /locus_tag="RHX21_004218"
     CDS             1576..1806
                     /gene="chaB"
                     /locus_tag="RHX21_004218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative cation transport regulator ChaB"
                     /protein_id="HDV1989324.1"
                     /translation="MPYKTKSDLPESVKHVLPSHAQDIYKEAFNSAWDQYKDKDDRRD
                     DASREETAHKVAWAAVKHEYAKGDDDKWHKKS"
     gene            1964..2659
                     /gene="chaC"
                     /locus_tag="RHX21_004219"
     CDS             1964..2659
                     /gene="chaC"
                     /locus_tag="RHX21_004219"
                     /EC_number="4.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415736.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-specific
                     gamma-glutamylcyclotransferase"
                     /protein_id="HDV1989325.1"
                     /translation="MITRDFLMNADCKTAFGAIEESLLWSAEQRAASLAATLACRPDE
                     GPVWIFGYGSLMWNPALEFTESCTGTLVGWHRAFCLRLTAGRGTAHQPGRMLALKEGG
                     RTTGVAYRLPEETLEQELTLLWKREMITGCYLPTWCQLDLDDGCTVNAIVFIMDPRHP
                     EYESDTRAQVIAPLIAAASGPLGTNAQYLFSLEQELIKLGMQDDGLNDLLVSVKKLLA
                     ENYPDGVLRPGFA"
     gene            complement(2703..3056)
                     /gene="ychN"
                     /locus_tag="RHX21_004220"
     CDS             complement(2703..3056)
                     /gene="ychN"
                     /locus_tag="RHX21_004220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE/F sulfur relay family protein YchN"
                     /protein_id="HDV1989326.1"
                     /translation="MQKIVIVANGAPYGSESLFNSLRLAIALREQESNLDLRLFLMSD
                     AVTAGLRGQKPGEGYNIQQMLEILTAQNVPVKLCKTCTDGRGISTLPLIDGVEIGTLV
                     ELAQWTLSADKVLTF"
     gene            3241..4635
                     /gene="ychO"
                     /locus_tag="RHX21_004221"
     CDS             3241..4635
                     /gene="ychO"
                     /locus_tag="RHX21_004221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415738.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inverse autotransporter invasin YchO"
                     /protein_id="HDV1989327.1"
                     /translation="MSRFVPRIIPFYLLLLVAGGTANAQSTFEQKAANPFDNNNDGLP
                     DLGMAPENHDGEKHFAEIVKDFGETSMNDNGLDTGEQAKAFALGKVRDALSQQVNQHV
                     ESWLSLWGNASVDVKVDNEGHFTGSRGSWFVPLQDNDRYLTWSQLGLTQQDDGLVSNV
                     GVGQRWARGNWLVGYNTFYDNLLDENLQRAGFGAEAWGEYLRLSANFYQPFAAWHEQT
                     ATQEQRMARGYDLTARMRMPFYQHLNTSVSVEQYFGDRVDLFNSGTGYHNPVALSLGL
                     NYTPVPLVTVTAQHKQGESGENQNNLGLNLNYRFGVPLKKQLSAGEVAESQSLRGSRY
                     DNPQRNNLPTLEYRQRKTLTVFLATPPWDLKPGETVPLKLQIRSRYGIRQLIWQGDTQ
                     ILSLTPGAQANSAEGWTLIMPDWQNGEGASNHWRLSVVVEDNQGQRVSSNEITLTLVE
                     PFDALSNDELRWEP"
     gene            complement(4636..5286)
                     /gene="narL"
                     /locus_tag="RHX21_004222"
     CDS             complement(4636..5286)
                     /gene="narL"
                     /locus_tag="RHX21_004222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator NarL"
                     /protein_id="HDV1989328.1"
                     /translation="MSNQEPATILLIDDHPMLRTGVKQLISMAPAITVVGEASNGEQG
                     IELAESLDPDLILLDLNMPGMNGLETLDKLREKSLSGRIVVFSVSNHEEDVVTALKRG
                     ADGYLLKDMEPEDLLKALHQAAAGEMVLSEALTPVLAASLRANRATTERDVNQLTPRE
                     RDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWVHQERIF"
     gene            complement(5279..7075)
                     /gene="narX"
                     /locus_tag="RHX21_004223"
     CDS             complement(5279..7075)
                     /gene="narX"
                     /locus_tag="RHX21_004223"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite two-component system sensor
                     histidine kinase NarX"
                     /protein_id="HDV1989329.1"
                     /translation="MLKRCLSPLTLVNQVALIVLLSTAIGLAGMAVSGWLVQGVQGSA
                     HAINKAGSLRMQSYRLLAAVPLSEKDKPLIKEMEQTAFSAELTRAAERDGQLAQLQGL
                     QDYWRNELIPALMRAQNRETVSADVSQFVAGLDQLVSGFDRTTEMRIETVVLVHRVMA
                     VFMALLLVFTIIWLRARLLQPWRQLLAMASAVSHRDFTQRANISGRNEMAMLGTALNN
                     MSAELAESYAVLEQRVQEKTAGLEHKNQILSFLWQANRRLHSQAPLCERLSPVLNGLQ
                     NLTLLRDIELRVYDTDDEENHQEFTCQPDMTCDDKGCQLCPRGVLPVGDRGTTLKWRL
                     ADSHTQYGILLATLPQGRHLSHDQQQLVDTLVEQLTATLALDRHQERQQQLIVMEERA
                     TIARELHDSIAQSLSCMKMQVSCLQMQGDALPESSRELLSQIRNELNASWAQLRELLT
                     TFRLQLTEPGLRPALEASCEEYSAKFGFPVKLDYQLPPRLVPSHQAIHLLQIAREALS
                     NALKHSQASEVVVTVAQNDNQVKLTVQDNGCGVPENAIRSNHYGMIIMRDRAQSLRGD
                     CRVRRRESGGTEVVVTFIPEKTFTDVQGDTHE"
     gene            7414..8805
                     /gene="narK"
                     /locus_tag="RHX21_004224"
     CDS             7414..8805
                     /gene="narK"
                     /locus_tag="RHX21_004224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate transporter NarK"
                     /protein_id="HDV1989330.1"
                     /translation="MSHSSAPERATGAVITDWRPEDPAFWQQRGQRIASRNLWISVPC
                     LLLAFCVWMLFSAVAVNLPKVGFNFTTDQLFMLTALPSVSGALLRVPYSFMVPIFGGR
                     RWTAFSTGILIIPCVWLGFAVQDTSTPYSVFIIISLLCGFAGANFASSMANISFFFPK
                     QKQGGALGLNGGLGNMGVSVMQLVAPLVVSLSIFAVFGSQGVKQPDGTELYLANASWI
                     WVPFLAIFTIAAWFGMNDLATSKASIKEQLPVLKRGHLWIMSLLYLATFGSFIGFSAG
                     FAMLSKTQFPDVQILQYAFFGPFIGALARSAGGALSDRLGGTRVTLVNFILMAIFSGL
                     LFLTLPTDGQGGSFMAFFAVFLALFLTAGLGSGSTFQMISVIFRKLTMDRVKAEGGSD
                     ERAMREAATDTAAALGFISAIGAIGGFFIPKAFGSSLALTGSPVGAMKVFLIFYIACV
                     VITWAVYGRHSKK"
BASE COUNT         2181 a         2158 c         2291 g         2279 t
ORIGIN      
        1 ctcaattcat cttcacttca tccctgaaat gtttgcaata aagagtacat tccggctttt
       61 caacagctgt tgcagtggtt tcgtgcaggt tgtggtacag gctcgcaatt ctgattaacg
      121 agctgtccag gtagtatgaa gaaatacaat aagcaggaat ttatcttatc tcccccgatt
      181 tccgtcatcg gaggagatat aactgtcagg caaatatcgt catcaaatag gcggcaaaca
      241 gtgccagatg cgctgcgcca ttgagcacgt tagtacgtcc ggtggagaag gagatatggc
      301 acagcactaa agaggccacc atcaccacca tttctggcgc accaagtgca aactgtaatt
      361 cgttacccgt cataaaggca attagcgtga cgacaggtac ggtaagcgaa atggttgcta
      421 acactgaacc aaagaacaga ttcatcgcgc gctggacctg gttgttcaac actgctttta
      481 acgcacctaa accttccggc gacagaatca acagagccac caggaagcca gtaaaggcga
      541 caggggcatt catgctgtcg agcaatgtct ccagcgggct ggcattcatt ttggtgactg
      601 caataacggc aatcagatgg ataatcaacc agatagcatg ccacacgctg ctatgggcag
      661 acggtttacc gtgatgcggg tcatcgtcat cactgtcatc ttcgtgctcg tagacaaaca
      721 aactttgatg cgttttggtc tggatcagca aaaatacgcc atacattgcc gcagaaatta
      781 atgctaccag taacgcctga ccggttgaaa aattcgccgc aggcagagcc attggaaata
      841 ccagtacgat tatcgccagg gggaacagcg caattaaata ctgcttgata ccaaacagat
      901 tcatatattg ggtggcaaac ttacgaccgc ccaacaataa tgaaaagcca accagcccac
      961 cggtaacaat cataatgatt gaatagagcg tatcacgcat tagcgttggc gcggcgtcgc
     1021 cggttgccat taaagctgaa atcaaactga cttcaagaat aaccactgaa aggctaagaa
     1081 taagcgaacc gtaaggttct cccaggcgat gggctaatac gtccgcatga cggacaacac
     1141 taaaggcgct acttaaaata ccaataagcg caagaagatt gatggcaatg accactggta
     1201 gtgtctggct gcttccccac aggaacagca ctaccagcgc cagaaccggg aaaataagcg
     1261 aagtctcctt gtggcgggtt tttaccgcct cttgagcatt tgacattatg gttatccctt
     1321 tgcagatgaa tttatcgaaa atgtaaaaaa taggtaggaa aaataacaga aagtgtctgg
     1381 atatcggtaa cattttacga atttttaccc cactgtcgat tttttactca ttgggacata
     1441 aaaataagta ttacgtttag acaatgtttg ttttagcgtt tcttaagaac agtctgacat
     1501 gaaaattcct atgttttggc aagagtagat attgttgacc acacttaatg ttcaactttg
     1561 taaaaggagt caacgatgcc gtataaaacg aaaagcgatc tgccggaaag cgtaaagcac
     1621 gttctaccgt ctcatgccca ggatatctat aaagaagcgt tcaacagcgc atgggatcaa
     1681 tataaagata aagacgatcg gcgtgatgac gccagtcgcg aagaaaccgc gcataaagtg
     1741 gcctgggctg ctgtgaagca tgaatatgcc aaaggggatg atgataaatg gcataaaaaa
     1801 tcgtaaaacc ggtagcttag ttaaagctat tcgtgcggtg ttgccttgca agtggtccgt
     1861 ggattgcata ttgtcccgtt agtggtttca aaatgagcag taaaaatgtc cggaagacac
     1921 caaaaagttg tcgcagggaa gtatgcagtg gcggaggtgt aaggtgataa cgcgtgattt
     1981 cttgatgaat gccgattgta aaacggcatt tggtgccatt gaagaatcac tcttatggtc
     2041 agcagagcaa cgggcggctt cgctggcggc gacgctggct tgtcgacctg atgagggacc
     2101 ggtgtggatc ttcggttatg gatcgttgat gtggaatccg gcactggagt ttaccgagtc
     2161 gtgcaccggt acactggttg gatggcatcg cgcgttttgc ctgcgcctga ccgccgggcg
     2221 cgggactgcg caccagccgg gacggatgct tgcactgaaa gagggcggac gcactacagg
     2281 cgtcgcctat cgactgccag aagagacgct ggagcaggaa ctaaccctgt tgtggaagcg
     2341 cgagatgatt accggctgtt atctgccaac ctggtgtcag cttgatcttg atgatggatg
     2401 cacagtaaac gccattgtgt ttattatgga cccgcgacat ccagaatatg aatctgacac
     2461 tcgcgctcag gtcatcgcgc cgttgattgc ggcggcgagc ggtccgctgg gaaccaacgc
     2521 acaatacctg ttttcactgg aacaggagct tatcaaactg ggaatgcagg acgatgggct
     2581 gaatgatttg ctggtatcgg taaaaaaact gctggcggag aattatccgg atggtgtgtt
     2641 acggccggga ttcgcctgag taaacttccc tcatagtggg gcgtcagacg ccccctcaaa
     2701 cattaaaatg tgagcacttt atcggctgac agcgtccatt gcgccagctc cacaagagta
     2761 ccgatttcca ccccatcaat aagaggaagt gtgctaatcc cgcgcccgtc ggtacaggtt
     2821 ttgcacaatt tcaccggtac attctgagcg gtaaggatct ccagcatttg ctgaatgttg
     2881 tagccttccc ctggtttttg cccgcgcaac ccggctgtga ccgcatcaga catcaggaac
     2941 agacgcagat ccagattgct ctcctgctct cgtaacgcaa tggccagccg caagctgtta
     3001 aacaaggatt cgctcccgta aggtgcgcca ttggcaacga tcacgatttt ttgcattatt
     3061 tactcctgta ttcagggaat tagacattca tcttctatct tactgcttct gcagcgtctg
     3121 accaatcggt cacattttta aggattttcc tgaaagcgcg agaaaatacg acaaaagttg
     3181 ccagtaatcg ttattcttta aggctatggt ttttcattat taccggaagt taccgacgtt
     3241 ttgagccgtt tcgttcctcg cattatcccg ttttatttac tcttgcttgt agcaggcggt
     3301 acagctaacg cacaatctac cttcgagcaa aaagcggcaa atccctttga taataacaat
     3361 gatggtctgc cggatttagg catggctccc gaaaatcatg atggggaaaa acactttgct
     3421 gaaattgtga aagatttcgg cgaaaccagt atgaatgata acgggctgga tactggcgag
     3481 caggcaaaag ctttcgcatt gggaaaagtc cgcgacgcgc ttagtcaaca ggttaatcag
     3541 cacgtagagt cctggctatc actgtgggga aatgccagtg ttgacgtcaa agtggataac
     3601 gaaggacatt tcaccggcag tcgtggaagc tggtttgtgc cgttacaaga taatgatcgt
     3661 tatctcacct ggagccagct tggtcttact cagcaggatg atgggttggt gagcaatgtg
     3721 ggcgttgggc aacgctgggc gcgcggcaac tggctggtgg gttataacac tttttatgac
     3781 aacttgctgg acgaaaatct tcagcgagcg ggctttggtg ccgaagcgtg gggcgaatat
     3841 ttgcgactat cggcaaactt ttatcagccg tttgctgcat ggcatgaaca gacagccacg
     3901 caggaacaac ggatggcgcg cgggtatgac ctgacagccc ggatgcgcat gccgttctat
     3961 caacacctca ataccagtgt cagcgtagaa cagtattttg gtgatcgtgt tgatttgttt
     4021 aactctggta cgggttatca caatcccgtc gcgttgagtc tgggattaaa ttacacccct
     4081 gtgccattag tcactgtgac ggcccagcat aaacagggtg aaagtggcga gaatcaaaat
     4141 aacctcgggc tgaatcttaa ttaccgcttt ggtgtaccgc tcaaaaaaca actttctgcg
     4201 ggtgaggttg ccgaaagtca gtcgttacgt ggtagtcgct atgacaatcc gcagcgaaat
     4261 aatctaccga ctcttgagta ccgacagcga aaaacgttaa cggtgtttct ggcgacaccg
     4321 ccgtgggatc taaaacctgg cgaaacagtg ccgctgaaat tacaaatccg cagtcgttac
     4381 ggtattcggc aactgatttg gcagggcgat acgcagatat taagtttgac gccgggcgca
     4441 caagccaaca gcgcggaggg ctggacgctg atcatgcctg actggcagaa cggggaaggg
     4501 gcaagcaatc actggcgatt gtcggtggtt gtggaagata accaggggca gcgtgtctcc
     4561 tccaatgaga tcacgctaac gcttgtcgaa ccgttcgatg cattgtcaaa cgacgaactg
     4621 cgctgggaac cgtaatcaga aaatgcgctc ctgatgcacc cataccgctg cttccacgcg
     4681 agacttgagc ttcattttct tcagcatgtg cttgacgtgc acttttactg tgctttcggt
     4741 gatatccagg cggcgggcaa tcatcttgtt cggcaaaccc tgggcaatca gcttgagaat
     4801 atcgcgctcg cgtggggtta actggttaac atcgcgctca gtagtggcac ggttagcgcg
     4861 caagctggcg gccagaacag gcgttaatgc ttcgcttaat accatttcgc cagcagctgc
     4921 ctgatgcaat gctttcagca gatcttccgg ttccatatct tttaacagat agccatccgc
     4981 gccgcgtttc agtgcggtga ccacatcttc ttcatggtta gagacgctga ataccacaat
     5041 gcgccctgag agggactttt cgcgcagttt atccagcgtt tccagaccgt tcatgccggg
     5101 catattgaga tctaacagga tcagatcggg atcaagagat tccgccagtt caataccctg
     5161 ttcgccatta ctcgcttcgc caaccacggt gatagctggt gccatactga taagctgttt
     5221 tacgccagtt cgcagcatcg ggtgatcgtc aatcagcagg atagtagccg gttcctgatt
     5281 actcatgggt atctccttgg acgtctgtga aagttttttc gggaataaag gtgaccacca
     5341 cttcggtgcc acctgattca cgacggcgga cgcggcaatc gcctcgtaaa ctttgcgcac
     5401 ggtcgcgcat tattatcatg ccgtagtgat tgctgcggat ggcattttca ggcacgccgc
     5461 agccgttatc ctgtacggtc agtttgacct gattatcgtt ttgcgccacc gtcaccacga
     5521 cctcactcgc ttgcgaatgt ttgagggcgt tacttaatgc ctcacgggca atttgcaaca
     5581 agtggattgc ctgatgcgaa ggcaccagac gaggcggcaa ttgataatcc agcttcaccg
     5641 ggaagccaaa tttggcgctg tactcttcgc aactcgcctc cagcgccgga cgtaatccag
     5701 gctcggtgag ctgcaagcgg aatgtggtga gcaattcacg caactgcgcc caggatgcat
     5761 tcagttcgtt acggatctga cttaacagtt cgcggctgct ttctggcagc gcatcgccct
     5821 gcatctgtaa acaactcacc tgcatcttca tacaagagag agattgggca atagaatcat
     5881 gcagttcgcg cgcaatggtg gcacgctctt ccatcacgat caactgttgc tgacgttcct
     5941 gatggcgatc caacgccagc gtggcggtga gttgttcaac cagggtatcc accagttgtt
     6001 gttgatcatg gctaagatga cgcccctgcg gcagggtcgc cagcaaaata ccgtactgcg
     6061 tatgagagtc agccagccgc cacttcaggg ttgtgccgcg atcgccaacg ggtaatacgc
     6121 cgcgcgggca gagctggcag cctttatcat cacaagtcat atctggttgg caggtaaact
     6181 cctgatgatt ctcttcatca tcagtatcat aaacccgcag ttcgatatca cgtagcaggg
     6241 ttaaattctg taagccgttg agtacaggtg acaggcgttc acacagcggg gcttgggaat
     6301 gcaaacggcg gttagcctgc cataaaaaag agaggatctg atttttatgc tccagcccgg
     6361 cggttttctc ctgaacccgc tgctcaagta cggcataact ttcggccagt tctgcagaca
     6421 tattgttcaa cgcagttcca agcatcgcca tttcgttgcg cccgctgatg tttgcgcgtt
     6481 gggtaaaatc gcgatgactg acggcactcg ccattgccag cagttgccgc cacggttgta
     6541 gcagtcgcgc ccgcaaccag ataatagtga acaccagtaa aagtgccata aataccgcca
     6601 ttacccgatg gaccagtacc actgtctcga tgcgcatttc cgtggtgcgg tcaaaaccag
     6661 ataccagttg atcaagcccg gcaacaaact ggctgacatc cgctgacacc gtttctcggt
     6721 tttgtgcacg catcaacgca gggatcagtt cattacgcca gtaatcttgt aaaccctgta
     6781 attgcgccag ttgtccgtct cgttctgctg ctcgagtcaa ctcggcgcta aatgccgttt
     6841 gttccatctc tttaattaag ggcttgtctt tctcgcttaa tggcactgct gccaacagac
     6901 ggtaactttg catgcgcagc gatcccgctt tgttgatcgc atgggcgctg ccctgaacgc
     6961 cttgcaccag ccagccagaa accgccatcc ctgccagtcc aatagcagta gaaagcaaca
     7021 caataagcgc aacctgatta accagggtga gcggagagag acaacgttta agcatgtaaa
     7081 cctcttcctt caggctttaa atgagcaata accttaatga atgtgacgat acattctgga
     7141 atggcagtat tctcggctat tggctgaagt atacccatac ccggaaagag ttactcctta
     7201 tttgccgtgt ggttagtcgc tttacatcgg taagggtagg gattctacag caccgtgaaa
     7261 aatctcataa tttttatgaa atcactgtac tcactatggg taatgataaa tatcaatgat
     7321 agataaagtt atcttatcgt ttgatttaca tcaaattgcc tttagctaca gacactaagg
     7381 tggcagacat cgaaacgagt atcagaggtg tctatgagtc actcatccgc ccccgaaagg
     7441 gctactggag ctgtcattac agattggcga ccggaagatc ctgcgttctg gcaacaacgc
     7501 ggtcaacgta ttgccagccg taacctgtgg atttccgttc cctgtctgct gctggcgttt
     7561 tgcgtatgga tgttgttcag cgctgttgcg gtgaacttac cgaaagtcgg ttttaatttt
     7621 acgaccgatc agctatttat gttgactgcg ctgccttcgg tttctggcgc gttattacgt
     7681 gttccatact cctttatggt tcctatcttc ggtggtcgtc gctggacggc gttcagcacc
     7741 ggtattctga ttattccttg cgtctggctg ggttttgccg tgcaggatac ctccacgcct
     7801 tatagcgtct tcatcatcat ctctctgcta tgcggctttg ctggcgcgaa cttcgcatcc
     7861 agtatggcaa acatcagctt cttctttccg aaacagaagc agggtggcgc gctgggtctg
     7921 aatggtggtc tgggaaacat gggcgtcagc gtcatgcagt tggttgctcc gctggtggta
     7981 tcactgtcga ttttcgcagt atttggtagc cagggcgtca aacagccgga tgggactgag
     8041 ctgtatctgg cgaatgcgtc ctggatatgg gtgccgttcc ttgccatctt caccattgca
     8101 gcgtggtttg gcatgaacga tcttgctacc tcgaaagcct ccatcaagga gcagttgccg
     8161 gtactcaaac ggggtcatct gtggattatg agcctgctgt atctggcaac cttcggctcc
     8221 tttatcggct tctccgcggg ctttgcaatg ctgtcaaaaa cgcagttccc ggatgttcag
     8281 attctgcaat acgctttctt cgggccgttt attggtgcgc tggcgcgttc tgcaggtggt
     8341 gcattatctg accgtctggg cggaactcgt gtcacgctgg tgaactttat tctgatggcg
     8401 attttcagcg gcctgctgtt cctgacctta cctactgacg ggcagggcgg aagcttcatg
     8461 gcgttcttcg cggtcttcct ggcgctgttc ctgacagctg ggctgggtag tggttccact
     8521 ttccagatga tttcagtgat ctttcgtaaa ctgacaatgg atcgcgtgaa agcagaaggg
     8581 ggttctgacg aacgtgcgat gcgtgaagcg gcaaccgaca cggcggcggc gttgggtttc
     8641 atctctgcga ttggcgcgat aggtggcttc tttatcccga aagcgttcgg tagctcgctg
     8701 gcattaacgg gttcgccagt tggcgcaatg aaagtatttt tgattttcta tatcgcctgc
     8761 gtagtgatta cctgggcggt atatggtcgg cattctaaaa aataaatctt aatatttgat
     8821 tatcctttgc gcggcatgat gtcgcgcttt ttttatgcgt catttagtta caacatactc
     8881 atattatatg gcttatttcg ccggatttc
//
LOCUS       DAPGUL010000160         8599 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.163, whole genome shotgun sequence.
ACCESSION   DAPGUL010000160 DAPGUL010000000
VERSION     DAPGUL010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8599
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.163"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..356
                     /locus_tag="RHX21_004225"
     CDS             <1..356
                     /locus_tag="RHX21_004225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001515283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989331.1"
                     /translation="GINGGNSLFASLIAPGGAGGGKSGVTNTNGGNGGVPSTGDINII
                     GGCGGDGQSGNIGVSGEGGTSYWGGGGRAGAGGGVSGKAYGSGGGGAYDAGYSGTSMT
                     GGKGAAGICIIEEFA"
     gene            356..766
                     /locus_tag="RHX21_004226"
     CDS             356..766
                     /locus_tag="RHX21_004226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000994390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HDV1989332.1"
                     /translation="MNTSYAVIENGMVVNVIVWDGEDEFTVPDNLQLINISDISEQPG
                     IGWAYSDGVFTAPPTPERSHDELVADAEQKKQSLIDAAMVNISVIQLKLQAGRKLTQE
                     ETTRLNVVLDYIEAVTATDTSTAPDVIWPELPEA"
     gene            complement(888..1376)
                     /locus_tag="RHX21_004227"
     CDS             complement(888..1376)
                     /locus_tag="RHX21_004227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001761054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV1989333.1"
                     /translation="MMMIYGMFVFELRTLPHQQLQQNKSWRHVKNERVNRSASWQYIG
                     AGDDRIVLSGVLYPEITGGEVSLSLLTTQAYTGRPWPLIDGVGQIYGMYVLTETSTTR
                     SEFDRYGKAKKIEFSLTLERCDEDLRERLQSSSFSDMLSGFKDKVTSSLNSAASSVKG
                     LF"
     gene            complement(1389..4196)
                     /locus_tag="RHX21_004228"
     CDS             complement(1389..4196)
                     /locus_tag="RHX21_004228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000853438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDV1989334.1"
                     /translation="MKTLDIRVAFSAVDRLTRPAENARRLMGQFGDSIQRTQGAIKNL
                     ERQARSFERARDAVSKADAGIVKARRQLNTLNQLQRTGTVLSEKQQKLMQQLSTRLER
                     LNESRTREIQKMRELGGELKRHGISLTGSDNTIQQAIRRTEQYNNQLERERQALARVT
                     RARERYSRAQETAGKLKTGGALAIGAVAAGGYAAGRFLQPAIGFGKEMSRVQALTRID
                     KNSPQFKELREQALKLGSETQFTAGDAASGQAFLAMAGFTPQAIQAALPGVLSMATAG
                     GMDLGETADIGSNILTQFGLSADQMDRVGDTLTAAFTRTNTDLRALGETMKYAGPVAG
                     KLGISLEQAAAMAGVLANMGIRGSDAGTAMRASLARLASPPKAAAEALKELGVSVSDA
                     GGKMRPMEDVLADLYKATRKYGEVDRVSFFKDIAGEEAFTSFMALVDAAGDGSLPKLR
                     KELEGARGEAERTAKVMANNLDGDLKSLSSAWEGLRIRIADLIDGPLRSVTQWLTRVV
                     SKVTALAQAHPALTRQLLIAGSALLAMTATVGSLSLAIGVLAGPLAKLRLGFSLLTGS
                     MNAVRVLPALWGMVTGSVSLLGGAIGALFSPVGLIVAALAGAAVLIWKYWDPIRAFFA
                     GVFSGIMERLNPLRETFERFGPVFDAIGSGISQVFNWFKSLLSPMESSKETLDKCTSA
                     GEIFGNVLGGALQLVLTPAKMLLDTLAWILEKLGVLPDEAERARKKIEDAQRAAILQD
                     KVALFQGDIAKINPPKSAENGNGTGGDKPKDNKPLTDSNTGTLRRLSKIADNTGKLVD
                     ETKKRIGPGDIVFKNLPRALAVRGEWQERKIAQVSKPAPAINITPVVPAPLPPALVPV
                     VAASSHPVAEAIRSPVASVPVTSRNREPVASGFGGEIHVHLHNVVTQNPRELAKLVGE
                     MVRAEVERRARAGRGSFYDKD"
     gene            complement(4183..4338)
                     /locus_tag="RHX21_004229"
     CDS             complement(4183..4338)
                     /locus_tag="RHX21_004229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GpE family phage tail protein"
                     /protein_id="HDV1989335.1"
                     /translation="MCFEHIEDFVADIAVIFNWSPAEIFMMTPGEVVSWRERAALRSG
                     NADNEDS"
     gene            complement(4347..4712)
                     /locus_tag="RHX21_004230"
     CDS             complement(4347..4712)
                     /locus_tag="RHX21_004230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV1989336.1"
                     /translation="MKETKNIDTENTVVADTVKETSERGVKLTQPIERGGEKITYVEI
                     TGAIEQAGSLRDLSLSDVLNLKAESMFTLLSRVTSPRLDEVTIKKMASRDFIQLCAVA
                     VNFLSGADSGGKNEQATEA"
     gene            complement(4767..5279)
                     /locus_tag="RHX21_004231"
     CDS             complement(4767..5279)
                     /locus_tag="RHX21_004231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail tube protein"
                     /protein_id="HDV1989337.1"
                     /translation="MAVPKHLRFFTLFVDGENEVGKVTSVTPPKLTRKTDSYRGGGMM
                     GAVSIDLGLDDSALDASFVMGGAVRALFLKYGGTIDGTLLRFAGEYYTDAESDLYEVE
                     MRGRVTEIDMGEAKQGEATSHTYAIKNTYYKLSVNDRPLWEIDLLNFIYRKDGKDIVP
                     DRIRSALGLG"
     gene            complement(5279..6463)
                     /locus_tag="RHX21_004232"
     CDS             complement(5279..6463)
                     /locus_tag="RHX21_004232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HDV1989338.1"
                     /translation="MSETRFHGARVTENTDLVTAINDVDSSVIGIVATADDADAKLFP
                     LNKPTLLTRVNDVLGKCGTTGTLYRALKAIADQVSTKVIVVRVAEHKEEDGKTQDQLV
                     IGGSESDGSYTGMYALLVAEQDESIGYRPRILAAPELDTEAVTKSLCVIAGKLRAFVY
                     ASCHGCNTMAEAITYRQKFNEREVMLLWPDFIAYNPKSGKNETFPAPAYACGLRAYID
                     HEQGWHKSLSNVPVKNVLGMSRHVFWSLQAEDSDANSLNNKEITTIIRRNGFRFWGNR
                     TPETNAYIFEVYTRTAQVLADSIAEAQFETIDSPLTPANVKDVISAIRAKLDSLVTAG
                     KLIGAECWYDVVDNSTTDLRQGRVRIRYKYTPVPPLEDMELYQTFTDEFFGPAFAVLG
                     GA"
     gene            6621..7730
                     /locus_tag="RHX21_004233"
     CDS             6621..7730
                     /locus_tag="RHX21_004233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001494339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage late control D family protein"
                     /protein_id="HDV1989339.1"
                     /translation="MTDTTMQLLSQGTDPVKMPDFDILAEGKTLSGVAERLMSLSLTD
                     NRGFEADQLTIMLDDADGQLQLPPRGAHLTVLIGWKGEPLTEKGTYIVDEIAHEGPPD
                     RLTVSARSADFRDEFNVKREVSWHDVTVERVVSAIAHRYGLKPQISEMLIDIEIDHAD
                     QTEESDISFLTRMAEMLGAITTVKSGNLLFIMPGGGVNAQGQPLPSFAITRSSGDRHQ
                     FRIADREAYTGVRAYWLDLNYGKKKKVSVKRRKPPKPKKEKSSSREGDYMEGAEGNVF
                     VLRKTYQNEQAARRAAAAKWQQLQRGAASFSITLARGRAELYPEMHGTVTGFKSEIDN
                     QDWIIAKAEHTIDNSGFTTQLELEAKIPEWIAETE"
     gene            7773..8033
                     /locus_tag="RHX21_004234"
     CDS             7773..8033
                     /locus_tag="RHX21_004234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001512982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ogr/Delta-like zinc finger family protein"
                     /protein_id="HDV1989340.1"
                     /translation="MFRCPLCGASARIRTSRPENDSNTVRQKYYQCNNLECGVCFSTL
                     EAFHKFTSKHASGVHSSEGIPWHDLPASHRGNNQMSLPLSQN"
     gene            8224..8364
                     /locus_tag="RHX21_004235"
     CDS             8224..8364
                     /locus_tag="RHX21_004235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hok/Gef family protein"
                     /protein_id="HDV1989341.1"
                     /translation="MSQKSLMAITFCVTAILIIWMLHGSLCEIRMSFWGAEFAAFLQC
                     KQ"
BASE COUNT         2051 a         2401 c         2193 g         1954 t
ORIGIN      
        1 acggcatcaa tggcggtaat agcttattcg catcgttaat tgctcctggt ggcgcaggcg
       61 gcggaaagtc aggagtcaca aacacaaacg gtggtaacgg aggtgtgccg agtactggcg
      121 atataaacat cattggtgga tgtggtggcg acggtcagtc cggaaatatc ggcgtcagcg
      181 gtgaaggcgg aacatcgtac tggggtggcg gtggacgcgc aggcgctggc ggtggtgtta
      241 gcggtaaggc atatggttca ggcggaggtg gcgcatacga tgctggttat agcggaacaa
      301 gtatgacggg cgggaaaggc gctgcaggga tttgtattat cgaggagttt gcataatgaa
      361 tacgtcatat gcagttattg aaaatgggat ggttgtgaat gtcattgtct gggatggcga
      421 ggatgaattc actgtgccgg ataatctgca gctcattaat atttctgata tcagtgagca
      481 gcccggaatc ggctgggcgt attcagacgg ggtatttact gcaccaccca ctccggaacg
      541 ttctcatgat gaactggtag ctgacgctga acagaaaaaa cagtcgttga tagacgcagc
      601 aatggtcaat atcagcgtga ttcagttaaa gctgcaggcc gggcgcaaac tgacgcaaga
      661 ggaaactacc cgacttaacg ttgtgctgga ttatatcgag gctgtgacgg caacagatac
      721 cagcaccgca ccggatgtca tctggcctga actgccggag gcgtaggcta ttctcctgct
      781 acctgataag aaattttaat cttctcagga ggaatacgtt tttatcagct ccagagaaac
      841 actttcagaa agaaccgcta atctgaccat tagcggtttt gcgttaatca gaacagccct
      901 ttaactgaac tggccgcgct gttaagagat gatgtcacct tatctttgaa gccggacagc
      961 atatcgctga acgatgagga ttgcagacgt tcccgcaaat cctcatcaca gcgttcaagg
     1021 gttagtgaaa attctatctt tttcgcctta ccgtagcgat caaactcaga gcgggtcgta
     1081 ctcgtttcgg tcaggacata catgccgtaa atctgcccga cgccatcaat cagaggccag
     1141 gggcgtccgg tatacgcctg cgtggtcagc agcgacagcg acacttcgcc gccagtaatt
     1201 tcaggataaa gcacgccgga aagaacaatg cgatcatcac ctgcaccaat atactgccag
     1261 cttgctgaac ggttaacgcg ttcatttttc acatgccgcc agcttttatt ttgctgtaac
     1321 tgctgatgcg gcaatgtacg cagctcaaaa acaaacatgc cgtagatcat catcatagcc
     1381 atggctcctc aatctttatc gtaaaaactg ccacgcccgg cacgagcgcg ccgttccact
     1441 tctgctctga ccatttcacc gaccagtttc gccagttcgc ggggattctg tgtaacaacg
     1501 ttatgcagat gaacatgaat ttcaccacca aatccggagg caacaggctc ccggttacgg
     1561 gaagttacag gaactgatgc cactggcgat cgtatggcct ccgccaccgg gtgggagctg
     1621 gccgcaacaa cagggaccag cgccggaggc agcggagccg ggaccacggg tgtgatatta
     1681 attgcggggg caggcttact gacctgcgca atcttccgct cctgccactc cccacgaacg
     1741 gcaagtgcgc ggggcaggtt cttaaagaca atatcgccgg ggccaatgcg ttttttcgtc
     1801 tcatcaacca gcttacctgt gttatcagca attttgctga gtctgcgtag cgtaccggta
     1861 ttgctgtctg tgagcggttt gttgtctttg ggtttatcgc ctccggtgcc attgccattt
     1921 tccgcagact tcggcggatt gattttcgca atgtctccct gaaacagagc aaccttgtcc
     1981 tgaagaatgg ccgcacgctg tgcgtcttcg attttctttc tcgccctttc cgcttcatcc
     2041 ggaagcacac cgagtttttc aagtatccac gccagcgtat ccagcaacat ttttgcaggc
     2101 gtcagaacaa gctgtagcgc gccaccaaga acgttaccga atatctcgcc agcactggta
     2161 catttatcca gcgtttcctt gctggactcc atcggtgaca gcagcgattt aaaccagtta
     2221 aacacctggc tgatcccgct tccgattgcg tcaaaaacag gaccaaaccg ttcaaaggtt
     2281 tcacgcaacg ggttcagcct ttccataatc ccgctgaaca ccccggcaaa aaatgccctg
     2341 atgggatccc agtatttcca gataagaacg gcagctccgg caagcgcagc cacgataaga
     2401 ccaaccggac tgaacagcgc cccgatagcg cctcccagta aagaaacgga acccgtcacc
     2461 attccccaca gtgctggcag aaccctgaca gcattcattg atccggtcag gagggaaaaa
     2521 ccaagacgca gttttgccag cgggccagca agcacaccaa tagccagcga caacgagcca
     2581 accgttgcag tcattgccag cagtgcactg cctgcaatca gtagctggcg cgtcagtgcg
     2641 ggatgggcct gcgccagcgc cgtcaccttt gataccacac gcgtgagcca ctgcgtgaca
     2701 gaacgcagcg gaccgtcaat cagatctgca atgcggatgc gcaacccttc ccatgcactg
     2761 ctgagtgatt tcagatcgcc gtcaaggttg ttggccataa cctttgccgt gcgttcagcc
     2821 tcaccgcgcg cgccttcaag ttcttttctc agtttgggta aggagccgtc acctgccgca
     2881 tcaacgaggg ccataaatga tgtgaaagcc tcttctccgg caatgtcctt aaagaacgat
     2941 acccggtcaa cttccccgta tttgcgggta gctttataaa ggtcagccag cacatcctcc
     3001 atcgggcgca ttttgccccc ggcatccgag acagacacgc caagctcttt cagcgcctct
     3061 gctgccgcct ttggcggtga tgccagacga gccaggctgg cacgcattgc cgtaccagca
     3121 tcactccccc tgatacccat attcgccagc acgcccgcca tcgctgcggc ctgctccagc
     3181 gatattccca gcttacccgc caccggacct gcatatttca tggtttcacc cagtgcgcga
     3241 aggtcagtgt tggtacgggt aaacgctgcg gtgagtgtgt cgccgacccg gtccatctgg
     3301 tcagcagaaa gaccgaactg cgtcagaata tttgagccaa tatccgccgt ctcaccgagg
     3361 tccataccgc cagccgttgc catgctcagt acgccaggga gcgcagcctg aatggcctgt
     3421 ggtgtgaagc cagccattgc aagaaatgcc tgcccactgg cggcatcgcc tgcggtgaac
     3481 tgcgtttcag agccaagttt taacgcctgc tcacgcagct ccttaaactg cgggctgttt
     3541 ttgtcgattc gcgtcagtgc ctgaacgcgg gacatctctt tcccgaaccc gatcgcaggc
     3601 tgcaaaaaac gcccggcagc atagccgccc gcagctaccg caccaattgc cagcgcacca
     3661 cctgttttca gttttcccgc tgtttcctgc gcgcgcgaat accgctcacg cgcccgcgtt
     3721 acacgcgcaa gcgcctgccg ttcgcgttca agctggttgt tgtactgttc ggtgcgtctg
     3781 atggcctgct ggatggtgtt atcgctgcct gtcagggaaa tgccgtggcg tttcagctct
     3841 ccgccaagct cccgcatttt ctgaatttcc cgtgtgcgcg attcattcag gcgttcaagc
     3901 cgggtgctta actgctgcat cagcttttgt tgtttttcgc tgagcactgt acccgtgcgt
     3961 tgtaactgat taagggtatt aagctggcgt cgtgctttca cgatgccagc atccgcttta
     4021 ctgacagcgt cacgggcgcg ctcaaatgaa cgcgcctgac gctcgagatt tttgatcgcc
     4081 ccctgcgttc gctggatgga gtcaccaaac tgccccatca ggcggcgggc gttttcggca
     4141 ggccgggtca gtctgtcaac ggcgctgaaa gcgacccgga tatcaagagt cttcattgtc
     4201 tgcattcccg ctgcgaagtg ccgcccgctc acgccagcta accacttcgc cgggcgtcat
     4261 catgaagatt tcggcgggcg accagttaaa aataacggca atatctgcca caaagtcttc
     4321 tatgtgctca aagcacacaa ccgtgatcag gcttccgtcg cctgttcgtt cttcccgcca
     4381 gagtccgcac cgctcaaaaa atttacggca accgcacata actgaataaa gtcacgggat
     4441 gccatttttt tgatcgtcac ttcatccagt cgcggtgatg tcacgcgtga cagcagcgta
     4501 aacatggatt ccgctttcag attcagcaca tcagacagcg acaaatctcg cagagatcca
     4561 gcctgctcaa tagctccggt gatctccaca tacgtgattt tttcgccgcc tcgctcaatt
     4621 ggttgggtaa gttttacgcc acgctcactg gtttctttca cagtgtcagc aacgaccgtg
     4681 ttttcggtat cgatgttttt cgtctctttc atcaggaaac tcctttcagt cagaggcgac
     4741 gcactgcgcc gcctgcatat tacttatcag ccaagcccga gcgcggaacg gatgcgatcg
     4801 ggcacaatgt ccttgccgtc cttccggtaa atgaagttca gcaggtcaat ctcccacaac
     4861 gggcgatcgt taacactcag cttgtagtag gtgtttttaa tggcgtaagt gtgtgatgtg
     4921 gcttcgccct gtttggcttc ccccatatca atttccgtca cacgtccgcg catttcgact
     4981 tcatacaggt cgctttctgc atcggtgtaa tattcacccg caaaacgcag cagcgtgccg
     5041 tcaatcgtgc cgccatactt aaggaacagt gcacgaacag ctccccccat gacaaagctc
     5101 gcatcaagcg cggagtcgtc cagaccgaga tcaatactta ctgcccccat catgccacca
     5161 ccccggtagc tgtcggtttt gcgcgtcagt ttgggcggcg tgacggatgt cactttaccc
     5221 acttcgtttt caccatccac aaacaacgta aaaaagcgaa gatgttttgg tacagccatc
     5281 aggcacctcc cagcaccgca aatgcgggac caaagaattc atcagtaaac gtctggtaaa
     5341 gctccatgtc ttccagcggg ggaacgggcg tatatttgta gcgaatacgc acacgcccct
     5401 gacgtaaatc cgtggtgctg ttatccacca cgtcatacca gcactccgcg ccaatcagtt
     5461 tcccggcagt cacaagtgaa tccagttttg ccctgatggc actgataaca tccttcacgt
     5521 tcgcaggcgt cagtggactg tcgatggttt caaactgcgc ttccgcaatt gaatcagcca
     5581 gcacctgtgc ggttcgggta tacacctcaa agatgtaggc gttcgtttcc ggtgtgcggt
     5641 tgccccagaa gcggaacccg ttgcgacgaa taatggtcgt gatttctttg ttgttgaggc
     5701 tgttggcatc gctgtcttcg gcctgcaacg accagaacac atgcctcgac atccccagca
     5761 catttttaac cggaacgttg gacagtgatt tgtgccagcc ctgctcatgg tcaatgtacg
     5821 cacgaaggcc gcacgcatag gcaggcgcgg ggaacgtttc gtttttgcca cttttcgggt
     5881 tgtaggcgat gaagtccggc cataagagca tcacctcacg ttcgttgaat ttctggcggt
     5941 aggtaatcgc ctcagccatc gtgttacagc cgtgacatga ggcatacaca aacgcgcgca
     6001 gtttacccgc aatcacgcac agggattttg ttaccgcctc cgtgtccagc tccggcgcgg
     6061 ccagaatacg cggacggtat ccgatgcttt catcctgctc tgcaacaagc agcgcataca
     6121 tccccgtata gctgccgtca gattcagaac caccgataac cagttgatcc tgcgtctttc
     6181 cgtcttcttc tttgtgttca gccacgcgaa cgacgatcac ctttgtgctc acctggtctg
     6241 caatggcctt aagcgcacga taaagcgtcc ccgttgtccc gcattttccc agcacgtcat
     6301 tgacgcgggt cagcagtgtg ggcttgttca gcgggaacag cttcgcgtcc gcatcatccg
     6361 ccgttgccac gataccgata acgctggaat caacatcgtt aatcgctgtt accaggtcgg
     6421 tattttccgt aacacgggca ccatgaaaac gagtttcact catagcttca gccccttgta
     6481 tccgttaaat gattcggcaa caatcatcac ccaccacgcg cgtaatctca cccctgcgcc
     6541 gttctcccga cccggcgaca acaaaaagca gtaaccccct ccgcacgcac atgcgaccat
     6601 gccgcacagg gagggaacag atgaccgaca ccaccatgca attgctcagt cagggcacag
     6661 accccgtgaa aatgccggat tttgatattc tcgcggaggg taaaacgctg tcaggcgtgg
     6721 cagagcgcct gatgagcctg tcactgaccg acaaccgggg atttgaggcg gaccagctca
     6781 ccatcatgct ggatgatgca gatggtcagt tgcagctacc gccacggggc gcgcacctga
     6841 cggttctcat tggctggaaa ggagaaccgc tgacagaaaa aggcacttac attgttgatg
     6901 aaatcgctca cgaaggaccg ccggacaggc tgactgtttc agccagaagc gcagattttc
     6961 gggatgaatt taacgttaaa cgtgaggtgt cctggcatga tgtgaccgtt gagcgtgtgg
     7021 tatccgccat cgctcatcgg tatggtctga aaccgcaaat cagcgaaatg ctgatagata
     7081 tcgaaatcga ccacgccgat cagactgaag aaagcgacat atccttcctt acgcgcatgg
     7141 cggaaatgct gggcgcaatc accacggtaa aaagcggtaa tctgttattc atcatgcccg
     7201 gtggtggcgt gaacgcacag ggccagccgt tgccatcgtt cgccatcaca cgcagcagcg
     7261 gcgatcgcca tcagttccgc attgctgacc gcgaggcgta tacgggggta cgcgcctact
     7321 ggcttgatct taattacggg aaaaagaaaa aagtcagcgt gaaacgccgc aaaccgccaa
     7381 aacccaaaaa ggagaaaagc agcagccgtg aaggtgatta catggaaggc gcggaaggca
     7441 atgtgtttgt gttacgcaag acttatcaga acgagcaggc agcaagacgc gcagcggcgg
     7501 caaagtggca gcagctacaa cgcggagccg catcattctc catcacgctg gcgcgtggac
     7561 gtgcagaact ctaccccgaa atgcatggca cggtaacagg atttaaaagc gagattgata
     7621 atcaggactg gatcattgca aaagccgagc acaccattga taacagcggc tttaccacgc
     7681 agcttgagct tgaggcaaaa atcccggaat ggatagcgga aacagagtga gcaacttaga
     7741 atagcggcag caccacgtta agggaggtcg ctatgttccg ttgtccgctt tgtggcgcat
     7801 ctgcccgtat ccgcaccagt cgtccggaaa atgattcaaa caccgtgcgg caaaagtatt
     7861 accagtgtaa caatctggaa tgcggcgtat gcttctcaac actggaagct ttccataaat
     7921 tcacatcaaa acacgcctcc ggcgttcact cttcagaagg tatcccgtgg catgatctgc
     7981 cagcttcaca caggggaaac aatcagatga gtttgccttt atctcagaat taacaggcag
     8041 aattgccgga gtaacaaaaa agcgatagat tacgcgcggg tgcctttcgg ctgatggtcg
     8101 gagggaatgc ccgaaggcca gatgtggaaa ggccccggaa aacatttctg tttaaccgag
     8161 gccctgacca tctaacctta gcaagtgata ggttagcgcc tccccaaaaa aggagcaagc
     8221 gctatgtcgc aaaaatcgct tatggccatc acgttctgcg tgacggcaat cctcatcatc
     8281 tggatgctac acggttcgct gtgtgaaata cggatgagct tctggggagc ggagtttgcg
     8341 gcgttcttac agtgtaagca gtaaggaaac cgcgacgggg gagtaatccc ccgtcaatcg
     8401 gttgccaggg taaggtcgat aaggcaccct atctcacagc tctaaatgca aaaattccat
     8461 gaaactgtgg gatttttgca tcacatactg atgcagacca gcccttctat atgcctcact
     8521 ctataccagc taatcaattg acacttatca ataaaaaaaa atctgataaa atcaaaatgt
     8581 tttgtaacaa atatcaact
//
LOCUS       DAPGUL010000161         8542 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.164, whole genome shotgun sequence.
ACCESSION   DAPGUL010000161 DAPGUL010000000
VERSION     DAPGUL010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8542)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8542)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8542
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.164"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(71..451)
                     /locus_tag="RHX21_004236"
                     /pseudo
     CDS             complement(71..451)
                     /locus_tag="RHX21_004236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611134.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
     gene            complement(869..2082)
                     /locus_tag="RHX21_004237"
     CDS             complement(join(869..1788,1788..2082))
                     /locus_tag="RHX21_004237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612262.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDV1989342.1"
                     /translation="MISSPQHKTGDLMNKKTKRTFTPEFRLECAQLIVDKGYSYRQAS
                     EAMNVGSTTLESWVRQLRRERQGIAPSATPITPDQQRIRELEKQVRRLEEQNTIFKKG
                     YRALDVRLAERFTIVARLSDSHSVVSLCSALEIHRSSYRYWRKRRDTVNPARVRLCSE
                     IRRAWNQSRGSAGARTLAEMLTQNGVPMSRYRAGRLMKYLNLSSCQPGKHQYKNARQE
                     HTCLPNLLERQFAVPEPDRVWCGDITYIWAENRWCYLAVVMDLFARRVIGWSLSANTD
                     TALISSALRMAYEVRGQPRDVMFHSDQGSQYTGLKYQQLLWRYRIKQSVSRRGNCWDN
                     SPMERFFRSLKTEWVPTDGYVGKDEARQQISGYILNYYNNVRPHHYNGGLTPEESENR
                     YRIYCKTVANIT"
     gene            2115..2346
                     /locus_tag="RHX21_004238"
                     /pseudo
     CDS             2115..2346
                     /locus_tag="RHX21_004238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904571.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(2587..3258)
                     /locus_tag="RHX21_004239"
     CDS             complement(2587..3258)
                     /locus_tag="RHX21_004239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000906845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDV1989343.1"
                     /translation="MLIPEIKQERLYQKIANLIIKLINDNVFPPGSFLPPERELAKQL
                     GVSRSSLREALIVLEISGWIIIQSGNGIIVSDNKHSPVDYTIEEILYVRDLVDSHCAR
                     LAALANNETIINKIELLHFRMENSIHENNVAEFYMLDKQFHLTISEASHNRVLLDMSR
                     MLWEQRVNIPYAGLDKRSGDKNVLIKLNQQHKAIIEAIRAGNADNALQRALLHLKYVR
                     EIIGY"
     gene            complement(3306..3665)
                     /locus_tag="RHX21_004240"
     CDS             complement(3306..3665)
                     /locus_tag="RHX21_004240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001361993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989344.1"
                     /translation="MICEHILISAYVFLYGAEGFIILFVETELSHAKIILENLRNKMA
                     GLRIQALVSERFSVTDNIGVDEYDFYPDYNLLIEREGVLLRQKSGSKPDRRLSATDDK
                     LLIFRHCHAKPVDPNQV"
     gene            3987..4269
                     /locus_tag="RHX21_004241"
                     /pseudo
     CDS             3987..4269
                     /locus_tag="RHX21_004241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447023.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
     gene            4424..4711
                     /locus_tag="RHX21_004242"
     CDS             4424..4711
                     /locus_tag="RHX21_004242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HDV1989345.1"
                     /translation="MTPAQRRQHYDAWRVSGMSRTAYARQHGINNKTFWHLCRAFSAD
                     DARGPAPADNRPAILPVTLSVSDTATLKLQCACVTASPAGIAAIIRELNLC"
     gene            4705..5043
                     /gene="tnpB"
                     /locus_tag="RHX21_004243"
     CDS             4705..5043
                     /gene="tnpB"
                     /locus_tag="RHX21_004243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HDV1989346.1"
                     /translation="MLSPHSLWLVREPADIRAGIDSLTRLATQAAGHPPREGEAFLFT
                     GKKRTRMKLLMWDRHGVWLCTRRLHQGAFRWPRDGDTTWSLTAEQFAWLTAGVDWLRL
                     SASPLQRWTE"
     gene            5118..6794
                     /locus_tag="RHX21_004244"
                     /pseudo
     CDS             5118..6794
                     /locus_tag="RHX21_004244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014837254.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            complement(6958..7137)
                     /locus_tag="RHX21_004245"
                     /pseudo
     CDS             complement(6958..7137)
                     /locus_tag="RHX21_004245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459923.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7247..7729)
                     /locus_tag="RHX21_004246"
     CDS             complement(7247..7729)
                     /locus_tag="RHX21_004246"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HDV1989347.1"
                     /translation="MDEKQLQALANELAKNLKTSEDLSQFDRLLKKLSVEAALNAEMT
                     HHLGYEKNQPRLGANSRNGYSTKTVITGDGPLELRTPRDRDGTFEPQLVKKNQTRITG
                     MDNQILSLYAKGMTTREIAAAFKELYDADVSPALTAEAGRLTGRILPRSSLIQRTSAK
                     "
     gene            complement(7872..8334)
                     /locus_tag="RHX21_004247"
                     /pseudo
     CDS             complement(7872..8334)
                     /locus_tag="RHX21_004247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001446915.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1977 a         2276 c         2185 g         2104 t
ORIGIN      
        1 gacaacaacc ttttttatat aaattattcc taatgttctt gcccccttat ttccagacag
       61 gggttgtatc ttaagttaac attacccgct gacgtcgata ttctcgcgga gagcgataac
      121 ccaacgcact atgcggatgg ttttcattgt aatgctcgat cgccactgca aggttatgca
      181 atgccgttct tacattcggt ttcggcatga acgcgatgta gtcttccttc atcgttttca
      241 cgaaccgttc tgccattcca ttactctgag ggctactgat tgccgttgtg cagggcttca
      301 gattcagctc tctggcgaac tgccgtgttt catgcgctct gtacgcttaa ccgttatctg
      361 tcagccactg gatggactgt tccggtactt tatcgccaaa gcgtttttct atcgctccta
      421 acatcacatc ctgcactgtc gctttatcgt aactccgaac cacacggcaa acaattctga
      481 gagttagagc gaaacagcaa atgttgctgt ataaaaaata gtcttagcgt gggaaaattt
      541 ccgaattcca agctgccccc tacgctggaa acgccgaaat ttccgataca gcgaatttgt
      601 tgatctttga agcatgtttg gcaggtttta acgtgtacgt ttatggtgca gtaagtgaga
      661 atttattcgt accagctatg gatacgttac gggcagtgat ttttcgcgcc aggcagctat
      721 ttctttgctg tccggttaac ggcggtctta cgtacaggtt gccgagcgca aaatttgtgc
      781 attccggaaa tttcggtggt tgcgacttgg tacccctttt attgttacag gaggactggg
      841 cttgtctgct accggtcagg tgtagtggtc aagtaatatt ggccacggtt ttacagtaaa
      901 tacggtatct gttctctgat tcttccggcg tcaacccacc gttgtaatgg tgaggcctga
      961 cgttattgta ataattcagg atataaccgc taatttgttg ccgggcctcg tccttgccta
     1021 cgtaaccatc cgtcggcacc cattctgttt tcagactgcg gaagaagcgt tccattggac
     1081 tgttatccca gcagtttccc cgtcgactga cactttgctt tatcctgtaa cgccagagaa
     1141 gttgttgata tttcagtcct gtatattgac ttccctggtc gctatggaac atgacgtccc
     1201 gcggctgacc acgcacctca tacgccatcc gcagggcact gcttatcagg gcagtatcgg
     1261 tattcgctga caggctccag ccgataaccc tgcgggcaaa aagatccatg acgaccgcca
     1321 gatagcacca gcgattttct gcccagatat acgtaatatc tccgcaccat accctatctg
     1381 gctcgggcac agcgaactgg cgctcaagca gattcggcag gcaggtatgt tcctgacgag
     1441 catttttgta ctgatgtttt ccgggctgac aactgctcag gttcagatat ttcatcagac
     1501 gcccggcacg gtaacggctc atcgggacgc cgttttgggt cagcatttca gccagcgtgc
     1561 gcgcccccgc agagccccta ctttggttcc acgcccggcg tatttcgctg cacaacctga
     1621 ctcgcgccgg attaaccgta tcgcgtcgtt ttcgccagta ccggtaactg ctgcggtgta
     1681 tttccagagc agaacagagg ctgacaactg agtggctgtc actcagtctg gcaactatcg
     1741 tgaaccgttc agcgagtcgg acatcaagag cgcggtagcc ttttttaata tcgtattttg
     1801 ttcctccagg cggcgaacct gcttttccag ttcgcggata cgttgctggt ctggagtaat
     1861 aggtgtggcg gagggcgcaa tcccctgacg ctctcgcctg agctggcgca cccaactctc
     1921 aagcgtggta gaaccgacat tcatcgcttc actggcttgt cgatatgagt agcccttatc
     1981 aacaattagc tgtgcacatt ccagcctgaa ttcaggggtg aaagtacgtt tggttttctt
     2041 gttcattaag tcacctgttt tgtgttgtgg tgaggatatc acctttaatc aggtggccaa
     2101 atttactgtg ccactacaat gtgcatgcaa gagtgcccac cgatatcacc cctgcagcgt
     2161 atcggtgaac tgtatgccat cgaggcagaa gtccggggat gtacagcaga acagagtctg
     2221 gcggcaagaa aagccagagc tgcgccactg atgcagtcac tgtatgactg gatacagact
     2281 cagatgaaaa cactgtcgcg tcactcggat acggcaaaag cgttcgcata cctgctgtta
     2341 cagtacctga ttcggcaagg caacgagaga tgagttcggg gtcgaggtaa tcccccagag
     2401 aagtcagtgg gttacgcaga gaatcgtaac gggataccag atcaagggcc tgtcccatgt
     2461 gcataaaaaa tccggaaacg agtgagcgtt tccggattct tacacagcca ctggatcggt
     2521 caactgatcc ttaactgatc ggcattacgg ctataccgga ggtatattta ttcagcgcag
     2581 aaaaggttaa taaccaatta tttctcgcac atacttcaaa tgtagcagtg cccgttgcaa
     2641 ggcattgtct gcatttcctg cacgaatcgc ctcaataatt gctttatgct gttgattaag
     2701 tttgataagt acattcttat cgccggaacg tttatccagc ccagcataag gtatattgac
     2761 acgctgctcc caaagcatcc gtgacatatc taacaacacc ctattatggc tggcttcaga
     2821 aatggtcaga tgaaactgct tatcaagcat ataaaattca gccacattat tttcatgaat
     2881 ggaattttcc attcggaaat ggagtaactc aattttatta attattgttt cattattagc
     2941 cagtgctgca agtcgggcac aatgactatc aactaaatca cggacataaa gaatttcttc
     3001 gatagtgtaa tcgactggag agtgtttatt atcactgaca ataatcccat taccagactg
     3061 aataataatc cagccagata tctcaagaac aataagagct tctctcagcg atgaacgact
     3121 aactcccagt tgtttcgcca gctcacgctc tggaggtaaa aaactacctg gcggaaagac
     3181 attatcattg atgagcttaa taataagatt cgctatcttt tgatagagcc tttcctgttt
     3241 aatttctgga attaacatgt gcctcccgct cgcttttatc gttagttatc tgacgaatta
     3301 tcatatcata cttggttcgg atctactggt ttcgcgtgac aatgacgaaa aatcagcagt
     3361 ttgtcatcag tagcagaaag acgtctatcc ggtttcgatc ctgacttttg gcgtaataaa
     3421 acgccctccc tttctatcaa taggttatag tcaggataaa aatcatattc gtcgacgcca
     3481 atattgtccg tgaccgaaaa cctttcactg actaaggctt ggatacgcaa accagccatt
     3541 ttgttacgta gattttcgag aatgatttta gcgtgtgata attctgtttc gacaaacaaa
     3601 ataataaatc cttcggcacc atagaggaaa acataagcac tgatgagaat atgctcacaa
     3661 atcatcgaag agaaattttt ctgtgtatta ccctcggaat tatgtctata acgattatta
     3721 attttcttga ggataatcaa tatccagcat ggcaagggag aattgtttac gtgagtgcaa
     3781 cgcgatagag attttccgcc gcataatcgt cagaataaag cgtcgattta atagttatgt
     3841 aagagaatct ttaccgtttc catgaatgta cctaaggtca ttagttcttt tctgacagct
     3901 tccggaaaat ttttatgtag agcagaaggc gtaacaagtc tatcctccct ccgcttcttt
     3961 cattttctgg tattgtgccg gggatacgcg tggcaatttc cgtggccatg ggggggcatc
     4021 ttactatacc tacgctgaag cgtgtgaagg tcagggtatg atgacatggt taaatactca
     4081 cggccactgc ctgacctact tgagcaacgt accgaagctg ctcagccccg ataaactaag
     4141 aagcgcagcg ctatgttcct gtcatccacg acagtaacca ggccctgcag agtactatgg
     4201 tacggttatc ataccggttc acccacgcaa accaaaagca caaaaaacgg tgttttcacc
     4261 gttgaaagat agctgcttgc ccgtatccat aatgaaacct tccatgcact caggacgttg
     4321 aatggtaagc atccggtgaa ctcgcattgc cggccgttgt gaaccacgcc attctgcagg
     4381 ttcttccttt atatgcaaaa gagagaaaac tgatggcaaa aaaatgaccc cggcgcagcg
     4441 acgccagcac tacgacgcct ggcgcgtcag cggcatgtcc cggaccgcgt atgcccggca
     4501 acacggcatc aacaacaaaa ctttctggca tctctgccgc gccttctccg ctgacgacgc
     4561 ccgtggcccc gctccggctg ataacagacc agccatcctg ccggtcaccc tctccgtcag
     4621 tgacactgcc accctgaaac ttcagtgcgc ctgcgtcacc gcctctccgg ccggcatcgc
     4681 cgccatcatc cgggagctta atctgtgctg agccctcatt ccctctggct cgtccgcgag
     4741 cctgctgaca tacgcgccgg catcgactcc ctgacgcgac tcgccactca ggccgccggg
     4801 catccgcccc gggaaggcga agccttcctc ttcaccggga aaaaacgcac ccgcatgaaa
     4861 ctcctgatgt gggaccgcca cggcgtctgg ctctgcaccc gccgcctgca ccagggcgcc
     4921 ttccgctggc cccgcgacgg cgacaccacc tggtcgctca cggcggaaca gttcgcctgg
     4981 cttaccgccg gcgttgactg gctgcgtctc tctgccagcc ccctgcagag gtggactgaa
     5041 taacctcctg tgccagaatc ataatacggg cagcttctta tcaggatgtt cccgcccgcc
     5101 tctgtcatca tggctgcatg acagatgaca tcctgaacac cacacaaaac cccgatgaac
     5161 tgcgccgtct ggcaacagcg ctgctgacgg cacaggcatg cgaatatgag cagcgccttc
     5221 ataacctgaa taccgtcaac accacgctgg aacagcgcct ccataacctg aataccgtca
     5281 ccaccacgct ggaacagcgt atccatgacc ttaatgccgc catgcaggca gaaaaaaccg
     5341 catatgaaca gcgcatccgg gagctggagg aggccctgaa gctggcccac cagtggcgct
     5401 tcgggcgtaa aagcgagcgc ctcccggcca gccagaaacc actggcagat gaggacgcgg
     5461 ccagcgatga ggctgatatc acccggcaac tgagcgacct gctgccggtg aaggagaaaa
     5521 ccgggaagaa gccggcccgt caccccctgc cggcacacct gccgcgacag gaaaccgtac
     5581 tcatgcctga gaccggtagc acctgtccgg actgcggaag tgaaatgcga catatccgcg
     5641 acgaggtgaa tgaggtgctg gagtatgtac cggcacactt cgtggtgaaa cggaccgtga
     5701 gaccgcagta cagttgcccg tgctgcgaca cggtgcacag tgccgtgctg ccgccggcag
     5761 tcatcgacaa agggcagccg ggtccgggtc tgctggcgca ggtggtgacc gcgaaggtgc
     5821 tggatcacct gtcactgcag cggcagcaga agatatacgc ccgtgaaggg gtacagttgc
     5881 cggaaagcac gctgacggac tggttcgggc cgacggcggc ggtgctgtcg ccgctggcgg
     5941 cagccctgaa acgtgacctg ctcaggcaac cggtgctgca ggcggacgag acgccgctgc
     6001 agatactgga tacgcggaaa gggaaagtcc ggaaagggta cctgtgagca tacgtgagtg
     6061 cggcgggcag tgcccgggac atcgtggtgt acgactgccg tccggggcgt gcggggcagt
     6121 atgcgtgtga gatgctgagc gggtggtcgg ggactctggt ggctgacggt tatgccggtt
     6181 accgggcgct gttccgtgac gggcaggaag gggcccctcc ggcggcaccg ggtatctgtg
     6241 aggcggggtg catggcgcac gtgcgcagaa agttcatgga gctgtacaga atgaacggca
     6301 gtccgggggc gaaggaggcg ctgaaacaga tacgggcgct gtatatcctg gagcagacca
     6361 tccggcagcg tccggcagag cagaaatggc gatggcgacg gcggtacgcg aagccgcaga
     6421 tggaggcgtt ccacagctgg ctgagggcga cggaaaagac gagcgcgccg ggtggcaggc
     6481 tgcacggtgc ggtgacgtat gccctgaagc gttggccggc gctggaaaca tacctgaatg
     6541 acggacgggt accgctggac aacaaccgga gtgagtagat gatgcgtccg gtggcgcagg
     6601 ggcggaagtc atggctgttc gcgggttcgc tgcggggagg agagcggctg gcggagctgc
     6661 tgacgctgct gcacacggcg aggctgaacg gtctggagcc agtagtctgg ctgcgtgatg
     6721 tgctggagaa gctgccgtca tggccggcgt cccggctgga tgaactgctg ccttaccgcc
     6781 atccggcgga ctgaatacgc cctgccataa cgccggtgat cgcgccatgc gagttcaccg
     6841 gatgcttacg ttgaatgtac gtttttggga tttactgacg gatatgaata accggcccat
     6901 gaaggagtac ggcaaaacca gcgcagaaca cttccgtatg cgctcatttg gggcgggatt
     6961 tgcacagtat tcagcttcca gaatctgtac acttttccac tcacacagct tcctcaaaat
     7021 acagcctatt gctctacgct tctctctgta gaacacctgt cttcggtatt ttggcgcaaa
     7081 aactatgatt cgccagtcct tcaacggaat cgtccatttc tgggacgcag actggattgc
     7141 cagccacacc acttttttca ccgagtcgtc tgtcgggaac acttacgctt tttgatcgca
     7201 tggcggatca cgctgtttag cgactcgatg gcattcgtcg tatagatcac tttgcggatg
     7261 tccgttggat aagcgaagaa cgtggcaaga ttcggccagt tagcctgcca gcttcggctg
     7321 tcagcgccgg tgaaacatct gcgtcataca gttctttgaa cgcagcagct atctcacgag
     7381 tggtcatccc tttggcatac aacgagagga tctggttatc catcccggta atacgggtct
     7441 gatttttctt taccagttgt ggttcgaagg taccgtcacg atcgcgcgga gtacgcagtt
     7501 ccagtggacc gtcgcctgtg ataacggtct ttgtggaata accgttgcgg gagttagctc
     7561 ctagtctggg ctgatttttc tcatacccaa gatggtgtgt catctcagca ttgagagcgg
     7621 cttcaacgct gagctttttc agcagccgat caaactgact gaggtcttca gaggttttga
     7681 ggtttttggc cagttcgtta gccagagcct gtaactgttt ttcatccata aattaacctt
     7741 catatgatgc tggattgaac atatcaaaat caggcgatta cacaaatcta tgtacaggtt
     7801 cagccgcttt attatcgagt tcggtgaccg ccaggacggt cacttctgag aaaaggcatt
     7861 tacacagaat cttaaacagg ttcacgcagc actggcgtca gggcattgat tgtcgctttc
     7921 actgatttgc tccggtttcc cgtggtcaga ctgcgcactt tctccttcag cctgttcaca
     7981 ctcgtcaggg ctattttcag cttcaactgt ttgtgccatg tcatactgta cccgaggaac
     8041 ttctgctccc acgggcgcgc caccgcgctc ttcttctcat tcactttctg cttcagtttg
     8101 ttctctacga cgtcctgata ccatgcagca atggccgccc tgcggcatgc cttcctgcca
     8161 tttctctctt tgcccgtccc ggactatttc ctctttcaag tagcggcgta tcagcctcag
     8221 cacccgcctg tcctttatcg tactggccag acgcgtcatc aggagtctgt gatccacacg
     8281 gtcgaagaac ttctccagat ttatatccac cacccaccgt ttgctgcccc gtatataatg
     8341 ctgtgcctat tgcactgcct gccatacgtt gcgtcccagc cggaaaccgt gcctagagtc
     8401 tgagaagctt ttgtccacga tggcgcttaa atgttgcgct atagctatag cctgctggat
     8461 aggcctatcc accactgtcg ggatccctaa ctaccttgaa aggcagttcg ccgtgaccga
     8521 gccaaatcag gtgtggtgcg gt
//
LOCUS       DAPGUL010000162         8484 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.165, whole genome shotgun sequence.
ACCESSION   DAPGUL010000162 DAPGUL010000000
VERSION     DAPGUL010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8484)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8484)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8484
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.165"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(156..422)
                     /locus_tag="RHX21_004248"
     CDS             complement(156..422)
                     /locus_tag="RHX21_004248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HDV1989348.1"
                     /translation="MKEFLFLFHSTVGVIQTRKALQAAGMTFRVSDIPRDLRGGCGLC
                     IWLTCLPGEEIQWVIPGQTEAIYCQQGSDWQCVVHYDSEASTRQ"
     gene            complement(419..1186)
                     /locus_tag="RHX21_004249"
     CDS             complement(419..1186)
                     /locus_tag="RHX21_004249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418754.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989349.1"
                     /translation="MAYSIGIDSGSTATKGILLADGVIMRRFLVPTPFRPATAITEAW
                     ETLREGLETTPFLTLTGYGRQLVDFADKQVTEISCHGLGARFLAPATRAVIDIGGQDS
                     KVIQLDDDGNLCDFLMNDKCAAGTGRFLEVISRTLGTSVEQLDSITENVTPHAITSMC
                     TVFAESEVISLRSAGVAPEAILAGVINAMARRSANFIARLSCEAPILFTGGVSHCQAF
                     ARMLETHLGMPVNTHLDAQFAGAIGAAVIGQRVRTRR"
     gene            complement(1196..2347)
                     /locus_tag="RHX21_004250"
     CDS             complement(1196..2347)
                     /locus_tag="RHX21_004250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418755.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase subunit D"
                     /protein_id="HDV1989350.1"
                     /translation="MSLVTDLPAIFDQFSEARQKGFLTVMDLKERGIPLVGTYCTFMP
                     QEIPMAAGAVVVSLCSTSDETIEEAEKDLPRNLCPLIKSSYGFGKTDKCPYFYFSDLV
                     VGETTCDGKKKMYEYMAEFKPVHVMQLPNSVKDDASRALWKAEMLRLQKTVEERFGHE
                     ISEDALRDAIALKNRERRALANFYHLGQLNPPALSGSDILKVVYGATFRFDKEALINE
                     LDAMTARVRQQWEEGQRLDPRPRILITGCPIGGAAEKVVRAIEENGGWVVGYENCTGA
                     KATEQCVAETGDVYDALADKYLAIGCSCVSPNDQRLQMLSQMVEEYQVDGVVDVILQA
                     CHTYAVESLAIKRHVRHQHNIPYIAIETDYSTSDIGQLSTRVAAFIEML"
     gene            complement(2463..3743)
                     /locus_tag="RHX21_004251"
     CDS             complement(2463..3743)
                     /locus_tag="RHX21_004251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 domain-containing protein"
                     /protein_id="HDV1989351.1"
                     /translation="MNKLIELRRAKMLALSLLLIAAATFVVTLFLPPNFWVSGVKAIA
                     EAAMVGALADWFAVVALFRRVPIPIISRHTAIIPRNKDRIGENLGQFVQEKFLDTQSL
                     VALIRRHEPALLIGNWFSQPENARRVGQHLLQIMSGFLELTDDARIQRLLKRAVHRAI
                     DKVDLSGTSALMLESMTKNDRHQVLLDTLIAQLIALLQRDKSRKFIAQQIVRWLESEH
                     PLKAKILPTEWLGEHSAELVSDAVNSLLDDISRDRAHQIRHAFDRATFALIDKLKNDP
                     EMAARADAVKSYLKEDEAFNRYLSELWGDLREWLKADINSEDSRVKERIARAGQWFGE
                     TLIADDALRASLNGHLEQAAHRVAPEFSAFLTRHISDTVKSWDAQDMSRQIELNIGKD
                     LQFIRVNGTLVGGCIGLILYLLSQLPALFPLGNF"
     gene            complement(3784..5016)
                     /gene="mdtM"
                     /locus_tag="RHX21_004252"
     CDS             complement(3784..5016)
                     /gene="mdtM"
                     /locus_tag="RHX21_004252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtM"
                     /protein_id="HDV1989352.1"
                     /translation="MPRFFARHAATLFFPMALILYDFAAYLSTDLIQPGIINVVRDFN
                     ADVSLAPAAVSLYLAGGMALQWLLGPLSDRIGRRPVLITGALIFTLACAATMFTTSMT
                     QFLIARAIQGTSICFIATVGYVTVQEAFGQTKGIKLMAIITSIVLIAPIIGPLSGAAL
                     MHFVHWKVLFAIIAVMGFISFVGLLLAMPETVKRGAVPFSAKSVLRDFRNVFCNRLFL
                     FGAATISLSYIPMMSWVAVSPVILIDAGGLTTSQFAWTQVPVFGAVIVANAIVARFVK
                     DPTEPRFIWRAVPIQLVGLALLIIGNLLSPHVWLWSVLGTSLYAFGIGLIFPTLFRFT
                     LFSNNLPKGTVSASLNMVILMVMSVSVEIGRWLWFNGGRLQFHLLAVVAGVIVVFTLA
                     GLLNRVRQHQAAELAEER"
     gene            5484..6440
                     /locus_tag="RHX21_004253"
     CDS             5484..6440
                     /locus_tag="RHX21_004253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001678496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HDV1989353.1"
                     /translation="MTNFTTSTPHDALFKSFLTHPDTARDFMEIHLPKDLRELCDLDT
                     LKLESASFVDEKLRALHSDILWSVETREGDGYIYVVIEHQSREDIHMAFRLMRYSMAV
                     MQRHIEHDKRRPLPLVIPMLFYHGSRSPYPWSLCWLDEFADPATARKLYTAAFPLVDV
                     TVVPDDEIVQHRRVALLELIQKHIRQRDLMGLIDQLVLLLVTECANDSQITALLNYIL
                     LTGDEARFKEFISELTSRMPQQRERIMTIAERIHNDGWLLGRERGRKEGKVEGERSLL
                     RLLLQNGADPEWIQKITGLSAEQMQALDQPLPESKRDPWIEY"
     gene            complement(6683..8095)
                     /locus_tag="RHX21_004254"
     CDS             complement(6683..8095)
                     /locus_tag="RHX21_004254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDV1989354.1"
                     /translation="MTRYQHLATLLAERIEQGLYRHGEKLPSVRSLSQEHGVSISTVQ
                     QAYQTLETMKLITPQPRSGYFVAQRKAQPPVPPMTRPVQRPVEITQWDQVLDMLEAHS
                     DSSIVPLSKSTPDVETPSLKPLWRELSRVVQHNLQTVLGYDLLAGQRVLREQIARLML
                     DSGSVVTADDIIITSGCHNSMSLALMAVCKPGDIVAVESPCYYGSMQMLRGMGVKVIE
                     IPTDPETGISVEALELALEQWPIKGIILVPNCNNPLGFIMPDARKRAVLSLAQRHDIV
                     IFEDDVYGELATEYPRPRTIHSWDIDGRVLLCSSFSKSIAPGLRVGWVAPGRYHDKLL
                     HMKYAISSFNVPSTQMAAATFVLEGHYHRHIRRMRQNYQRNMALYTCWIREYFPCEIC
                     ITRPKGGFLLWIELPEQVDMVCVARQLYRMKIQVAAGSIFSASGKYRNCLRINCALPL
                     SETYREALKQIGEAVYRAME"
     gene            8272..8436
                     /locus_tag="RHX21_004255"
     CDS             8272..8436
                     /locus_tag="RHX21_004255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1127 domain-containing protein"
                     /protein_id="HDV1989355.1"
                     /translation="MEFHENKAKTPFIRLVQLWQAVRRWRRQMQARRVLQQMSDERLR
                     DIGLRREDVE"
BASE COUNT         2202 a         2236 c         2160 g         1886 t
ORIGIN      
        1 tgtataatgt attttagacg taaaatagta aggtgctatc aaaaatcgct cattttgtgg
       61 atgggaaata tttcacggca gacgagatat ttaatacaac ttccttcatg caggattatg
      121 cgcagccaat tatccgcgcg ttatatttaa aggtcttatt gcctggttga cgcttctgaa
      181 tcgtaatgca ccacgcactg ccagtcgctg ccctgctggc aatatatcgc ttcggtctgc
      241 ccagggatca cccattgtat ttcctcgccg ggcagacagg tcagccaaat gcataacccg
      301 cagccgccgc gtaaatcacg gggaatatcg ctgacgcgaa aagtcatgcc cgctgcctgc
      361 aacgccttgc gggtttgtat cacgccgacc gtggagtgaa ataaaaataa aaactctttc
      421 atcggcgtgt cctcactcgt tgaccaatta ccgccgcgcc aattgcgcca gcaaattgcg
      481 catcaagatg ggtatttacc ggcattccca ggtgagtttc caacatccgg gcaaacgcct
      541 ggcaatgact aacgccacca gtaaacagaa tcggcgcttc acaggagaga cgagcaatga
      601 aattggcact ccgccgcgcc atcgcgttaa tcactccagc gagaatcgct tctggcgcga
      661 cgcccgctga gcgcaagctg atcacttctg attcggcaaa caccgtacac atactcgtga
      721 tggcgtgcgg cgtgacattt tcggtaatgc tgtcgagttg ctcgacgctg gtgccaagcg
      781 tgcgcgagat cacctccagg aaacgcccgg tgcccgccgc gcatttgtca ttcatcagga
      841 aatcgcacag gttaccgtca tcatcaagct gaatcacttt gctgtcctga ccaccgatgt
      901 cgattactgc gcgcgttgct ggcgcaagaa accgtgcgcc cagcccgtga caggagattt
      961 ccgtcacctg tttatcggca aaatccacca gttgccgtcc gtagccggtg agcgtcagaa
     1021 acggcgttgt ttctaaccct tcgcgcagag tttcccaggc ttcagtaatt gctgttgccg
     1081 ggcgaaaggg tgttggaacg aggaaacggc gcataatcac gccgtctgcc agtaagatcc
     1141 ctttggtggc ggttgagccg gaatcaatgc caatcgaata tgccactgcc actccttaca
     1201 gcatctcaat aaaggccgcg acacgggtgc tgagctgccc gatatctgag gtggagtagt
     1261 ctgtttcaat agcgatataa ggaatgttgt gctgatgacg cacatgacgt ttaatcgcca
     1321 gcgattccac cgcgtaggta tggcacgcct gcaaaatcac atcaactacg ccatcgacct
     1381 gatattcttc aaccatctgg ctgagcattt gcaggcgctg atcgttcggc gaaacacagg
     1441 agcagccaat cgccagatat ttatccgcca gcgcgtcgta gacatcgccc gtttctgcca
     1501 cgcattgctc ggtcgctttc gccccggtgc agttttcata accgacaacc cagccgccat
     1561 tctcttcaat cgcgcgcacc actttttctg ctgcgccgcc aatcgggcag ccggtgatta
     1621 aaatgcgcgg acgcgggtcc agtcgctggc cttcttccca ctgctgacga acgcgggcgg
     1681 tcattgcatc cagttcattg atcaacgcct ctttatcgaa ccggaaggtt gcgccgtaaa
     1741 ccactttcag aatgtcgctg ccgctaagcg ccggaggatt taactgccca agatgataaa
     1801 aattagccag tgcgcgacgt tcgcggtttt tcagcgcaat ggcatcgcgc agagcatctt
     1861 cgctaatttc gtgcccaaaa cgttcttcta ccgttttttg caagcgcagc atctcggctt
     1921 tccacaatgc acgcgaggca tcgtccttaa cgctgttcgg taactgcatc acatgaacag
     1981 gcttaaactc cgccatgtat tcatacattt tctttttgcc gtcgcaggtg gtttcaccga
     2041 ccaccagatc agaaaagtag aagtaggggc atttatcggt tttgccgaag ccgtagctgc
     2101 ttttaatcag cgggcagagg ttgcgcggca gatctttctc ggcttcttca atggtttcat
     2161 cagaggtgga acagagcgaa accacaactg caccggctgc catcgggatc tcttgcggca
     2221 taaaggtgca gtaggtgcca accagcggaa tgccgcgctc cttgagatcc atgacggtga
     2281 gaaagccttt ctggcgagct tcagagaact gatcgaaaat ggcgggtaga tcggtgacaa
     2341 gtgacatgat tttccttccc cgtaccacgg gagataatga aaagaggcca cattattacc
     2401 attcttttag tgtggtttat ttgatctctc tcgcggttag ccacttagtt tttcatggat
     2461 ttctaaaaat tgccgagggg gaacaaggcc gggagctgcg aaagcaaata caaaattagc
     2521 ccaatacaac cgccaaccag cgtaccgttg acacggataa actgcagatc tttgccgata
     2581 tttaactcga tttgccgcga catatcctgc gcatcccagc tttttaccgt atcgctgata
     2641 tgtcgcgtca ggaatgcgga aaactcaggc gcgacgcggt gcgcggcttg ttccagatga
     2701 ccatttaacg acgcccgcaa ggcatcatcg gcaattaacg tttcgccaaa ccattgaccc
     2761 gcccgcgcga tacgttcttt cacacgagaa tcttcactgt tgatatccgc tttcagccat
     2821 tcccgtaaat ctccccacaa ttcactgaga tagcggttaa aagcttcgtc ttctttcaga
     2881 tagcttttta cggcatcggc tcgcgctgcc atttcaggat cgtttttcag cttgtcgatc
     2941 agggcaaagg tggcgcgatc aaacgcatgg cggatctgat gcgcacgatc gcggctgata
     3001 tcatcaagca aagaattcac cgcgtcagaa accaactccg cgctatgttc gcccagccat
     3061 tcagtgggca aaattttggc tttcagtgga tgctcgctct ccagccagcg aacaatttgc
     3121 tgggcgataa acttgcgcga tttatcgcgc tggagaaggg cgatcaactg tgcgatcagc
     3181 gtatccagca gcacctgatg acgatcgttt ttggtcatac tctccagcat caacgcactg
     3241 gtgccagaaa gatcaacctt atcaatcgcc cggtggaccg cgcgcttaag caggcgctga
     3301 atacgcgcat catcggtcag ttcaagaaaa ccgctcatga tctgcaacag atgctgacca
     3361 acgcggcggg cgttttctgg ctgactaaac cagttgccaa tcaacaacgc cggttcgtga
     3421 cgtcgaatca atgccaccag cgattgggta tcgagaaatt tttcctgcac gaactgaccg
     3481 agattttcgc caatccggtc tttattacgc gggataatcg ccgtatgacg agaaatgatc
     3541 ggaatcggca cgcggcgaaa cagcgccacc accgcaaacc agtccgccag cgcgccgacc
     3601 atcgccgctt cagcaatcgc cttcacgccg ctcacccaaa aattgggcgg caaaaacagc
     3661 gtaacgacaa aggtagcagc ggcgataagc agtaaagaga gcgccaacat tttggcgcgt
     3721 ctgagttcaa tgagtttatt cataacgtta agaatagagc ctgacggtag gatcgcgcaa
     3781 aaatcaccgc tcctccgcca gctcggcagc ctgatgttgg cgcacgcgat taagcaatcc
     3841 ggccagggtg aaaacgacga taacgcctgc cacaacggct aacagatgaa actgcaagcg
     3901 accgccgtta aaccacagcc agcggccgat ttcgaccgag acagacatca ccatcaggat
     3961 caccatattc agcgatgcgg agacggtccc tttcggtaag ttattggaaa acagcgtaaa
     4021 gcggaataag gtcgggaaga tcaaaccaat cccgaaagca tacagactgg tgcccagcac
     4081 cgaccacagc cagacgtgcg gtgacagcag attgccgata atcaacagcg cgaggccgac
     4141 cagttgaatg ggtacggcac gccagataaa gcgcggttcg gtcggatctt taacgaaacg
     4201 cgccacgatg gcattcgcga caatcaccgc gccgaacacc ggaacctgtg tccaggcgaa
     4261 ctgcgaagtt gttaagccgc ctgcgtcaat caggatcacc ggcgagacag ccacccaact
     4321 catcattggg atatagctta aagagatggt tgctgcgcca aagaggaaca gccgattgca
     4381 aaagacatta cgaaaatcgc gcaagacgct tttggcgcta aatggaaccg cgccgcgctt
     4441 caccgtctct ggcatcgcca gcagtaagcc aacaaatgag ataaaaccca taaccgcaat
     4501 gatggcaaaa aggactttcc agtgcacaaa gtgcatcaga gctgcgccgg aaagcgggcc
     4561 gataatcggc gcaatcagta cgatggaggt gataatcgcc atcaacttga tcccttttgt
     4621 ctgtccgaac gcctcctgca ccgtgacata accaacggtg gcaataaaac agatactggt
     4681 gccctgaatt gcacgcgcga taagaaattg tgtcattgac gtggtgaaca ttgtcgcggc
     4741 gcaggcaagg gtaaaaatta acgccccggt aatcagcacc ggcctgcggc caattctgtc
     4801 ggaaagcggc cccagcagcc actgtaacgc cataccgcca gcaagataga gactgacggc
     4861 agcaggggcc agactgacat cggcattaaa atcacggacc acattaatga tccctggctg
     4921 gatcagatcc gtcgacagat acgcagcaaa gtcatacaaa atcaacgcca tcgggaaaaa
     4981 cagcgtggcg gcatggcggg caaaaaaacg tggcataaca aacaactcct tgtccggaga
     5041 accccaatgg ggaaaacgaa attcaatacc gtcggtaatg acgaaaggca ggcgagaagg
     5101 acaaatgtac tgaatttcat gtaatcaacc acactgcctg tgaacacaca gacagagaaa
     5161 taccttctga ctccaggtca gaatgtataa cgattacaaa tagtcatcag cacattacac
     5221 ctcttgaatt gatgggttgc atagaaaata tacaccttaa gtgtaattaa aatttgcggt
     5281 taatcaaaag agcgcggtgg aaagggggaa tatctgccgg gtacaggaaa tgtaaaatgc
     5341 gagcctgttt ccggaaaaat gtatcgtttg cagaagaata aaaatagcct ggaaagcacc
     5401 tcggggaatg ggaaattgcc gggtgagaat ggttttgtta gtcgctaaag tcgggccatc
     5461 ttatcaacag gtgacggatc gccatgacaa acttcacgac cagtacgccg catgacgcat
     5521 tatttaaatc ctttctcacc caccctgaca ccgcgcggga ttttatggag atccatttac
     5581 ctaaagattt acgtgaactg tgcgatctcg acactttaaa actggaatcc gccagcttcg
     5641 tcgatgaaaa attgcgggcg ctacactccg atattctgtg gtcggtagag acccgtgaag
     5701 gtgatggcta tatctatgtg gtgattgaac atcagagccg tgaggatatt catatggcct
     5761 ttcgcctgat gcgctattcc atggcggtga tgcagcgcca tatcgagcat gataaacgcc
     5821 ggccgctacc gctggtcatc ccgatgctgt tttatcacgg tagccgtagt ccttatccct
     5881 ggtccctgtg ctggctggac gaatttgccg acccggctac cgcacggaag ctttataccg
     5941 ccgcgttccc gctggtggat gtcactgtcg tgccagacga cgagattgtg cagcatcgca
     6001 gagtcgccct gttggagttg atccaaaagc atattcgcca gcgcgatctg atggggctta
     6061 tcgaccaact ggtattatta ctggttacag agtgtgctaa tgacagccag ataactgcgc
     6121 tgttaaatta cattttactg actggcgatg aagcgcgttt taaagagttt atcagcgaac
     6181 taaccagtcg aatgccacaa caaagggagc gaataatgac gattgcagag cgaattcata
     6241 atgatggatg gctgttggga agggagaggg ggaggaaaga agggaaagta gaaggggaac
     6301 ggagcctcct ccgattgttg ttgcagaatg gggcagatcc tgaatggata caaaagatta
     6361 ccggactctc ggcagagcaa atgcaggcat tagatcagcc cttgcctgaa agcaagcgcg
     6421 atccatggat cgagtactaa tcagagactg atggcaaacg caaagctgcc tgatgcgcta
     6481 cgcttatcag gtctacataa cccattaaat atattgaact ttaaaaattt tgtagacctg
     6541 gtaaggcgtt cacatggcat ccggcatgaa cgaagcgcat tttgcctaag ccatgctgga
     6601 acgtggagat gaccctgcaa agataaaacg agtcacacgc gattcgtgag aggaaatcag
     6661 ggggctcacc actatttcga attcattcca ttgcccgata cacggcttcg ccaatttgct
     6721 tcagtgcttc gcgataggtt tcgctgagcg gcaaagcgca gttgatgcgc agacaattac
     6781 ggtatttgcc ggaagccgag aaaatcgagc ctgccgccac ctggattttc atgcggtata
     6841 gctgccgcgc aacgcagacc atatcgacct gttcaggcaa ttctatccac agtaaaaatc
     6901 cgcctttcgg gcgcgtaata cagatttcgc agggaaaata ttcccgtatc cagcaggtat
     6961 aaagcgccat attgcgctga tagttctgcc gcatccgccg gatatggcga tgatagtgac
     7021 cttccagcac aaacgttgcc gccgccattt gcgtggacgg tacattaaag ctgctgatgg
     7081 catatttcat atgcagcagt ttatcgtgat agcgccccgg tgcgacccaa cccacgcgca
     7141 ggccaggtgc aatactttta ctgaacgagc tgcacagtag cactcgcccg tcgatatccc
     7201 aggaatgaat ggtccgcggg cgcggatact ccgtcgccag ttcgccgtag acatcatctt
     7261 caaaaatcac aatatcatga cgctgagcga gagagagaac ggcccgtttg cgcgcgtccg
     7321 gcataataaa tcccagcgga ttattacagt ttggcaccag aatgatgcct ttaatcggcc
     7381 actgttccag cgccagttcc agcgcttcaa cgctgatgcc tgtttctgga tcggttggga
     7441 tttcaatcac tttcacgccc atgccacgca gcatctgcat cgaaccgtaa taacaggggg
     7501 attcgaccgc gacaatatcg cccggtttac acaccgccat taacgccagc gacatcgagt
     7561 tatggcagcc gctggtgatg atgatgtcat cggcagtgac caccgagccg ctgtcgagca
     7621 tcaggcgggc aatctgctct cgcaacactc gctgaccggc taacaagtca taaccgagaa
     7681 cggtttgcag attatgctgc accacccggc ttagctcccg ccacagcggt ttcaggctgg
     7741 gcgtttcgac atccggcgtg cttttactta acggaacaat ggaactgtcg ctatgcgcct
     7801 ccagcatatc cagcacctga tcccactggg taatttccac cgggcgctgc accggacgcg
     7861 tcatcggcgg cactggcggc tgggctttac gttgtgcgac aaaataaccc gaacgcggct
     7921 gtggggtgat gagcttcatc gtctccagcg tctgatacgc ctgctgcacg gtgctgatgc
     7981 tgacgccgtg ctcctgactt aagctgcgca ccgacggcaa tttctccccg tgacgataca
     8041 gcccctgctc aatccgctcg gcaagcagag tcgccagatg ttgataacgc gtcatgctgt
     8101 attccttatg tggaccatac agagagaaaa accggtacag atgaggctaa aaaaccggat
     8161 gcagatgctg ttttaacctg tctgtatgtt aaataaaact aatatttgca tctgtattgt
     8221 gaactgccag aagacggatg atgaagcctc tgaaagatga ggaggcagca gatggaattt
     8281 cacgaaaaca aagccaaaac gccgtttatc agacttgtgc aactctggca ggcggtgagg
     8341 cgttggcggc ggcaaatgca ggcccggcgg gtgttacagc agatgagtga tgagcggttg
     8401 agggatattg ggttacgcag ggaggatgtg gagtgataga ggatgttgag aataaatcag
     8461 gatattaact ttttatatgt accc
//
LOCUS       DAPGUL010000163         8433 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.166, whole genome shotgun sequence.
ACCESSION   DAPGUL010000163 DAPGUL010000000
VERSION     DAPGUL010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8433
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.166"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..296
                     /locus_tag="RHX21_004256"
     CDS             <1..296
                     /locus_tag="RHX21_004256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HDV1989356.1"
                     /translation="RLGFRTFIRTQEKNSGSHGDDFEPFVEMNWIHNSKDFAVSMNGV
                     KVEQDGASNLGEIKLGVNGNLNPAASVWGNVGVQLGDNGYNDTAVMVGLKYKF"
     gene            complement(353..688)
                     /locus_tag="RHX21_004257"
     CDS             complement(353..688)
                     /locus_tag="RHX21_004257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmgD family protein"
                     /protein_id="HDV1989357.1"
                     /translation="MMMKKFALLAGLFVFAPMTWAQDYNIKNGLPSETYITCAEANEM
                     AKTDSAQVAEIVAVMGNASVASRDLKIEQSPELSAKVVEKLNQVCAKDPQMLLITAID
                     DTMRAIGKK"
     gene            complement(692..1036)
                     /locus_tag="RHX21_004258"
     CDS             complement(692..1036)
                     /locus_tag="RHX21_004258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415690.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper family protein"
                     /protein_id="HDV1989358.1"
                     /translation="MKKKILAFGLISALFCSTPAMADMNRTTKGALLGAGVGLLTGNG
                     VNGVLKGAAVGAGVGAVTEKGRDGKNARKGAKVGAAVGAVTGVLTGNGLEGAIKGAVI
                     GGTGGAILGKMK"
     gene            complement(1038..1211)
                     /locus_tag="RHX21_004259"
     CDS             complement(1038..1211)
                     /locus_tag="RHX21_004259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989359.1"
                     /translation="MSYSSFKIILIHVKNIIPIITATLILNYLNNSERSLVKQILIED
                     EIIVCATYLIPDI"
     gene            1312..1497
                     /locus_tag="RHX21_004260"
     CDS             1312..1497
                     /locus_tag="RHX21_004260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989360.1"
                     /translation="MSRRYSSATITLVILFCRRPHCRKISVRQYYLKRVIFYPTTLQR
                     TACKKCLFLMRDIIISS"
     gene            1458..1577
                     /locus_tag="RHX21_004261"
     CDS             1458..1577
                     /locus_tag="RHX21_004261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001131457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDV1989361.1"
                     /translation="MPLSYAGYHHFIMMSLVSGEHNTPALSLQDESPGLVPAG"
     gene            1612..1956
                     /locus_tag="RHX21_004262"
                     /pseudo
     CDS             1612..1956
                     /locus_tag="RHX21_004262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311542.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
     gene            complement(2328..2594)
                     /gene="minE"
                     /locus_tag="RHX21_004263"
     CDS             complement(2328..2594)
                     /gene="minE"
                     /locus_tag="RHX21_004263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HDV1989362.1"
                     /translation="MALLDFFLSRKKNTANIAKERLQIIVAERRRSDAEPHYLPQLRK
                     DILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEELK"
     gene            complement(2598..3410)
                     /gene="minD"
                     /locus_tag="RHX21_004264"
     CDS             complement(2598..3410)
                     /gene="minD"
                     /locus_tag="RHX21_004264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020801817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HDV1989363.1"
                     /translation="MARIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVIDFDIGLR
                     NLDLIMGCERRVVYDFVNVIQGDATLNQALIKDKRTENLYILPASQTRDKDALTREGV
                     AKVLDDLKAMDFEFIVCDSPAGIETGALMALYFADEAIITTNPEVSSVRDSDRILGIL
                     ASKSRRAENGEEPIKEHLLLTRYNPGRVSRGDMLSMEDVLEILRIKLVGVIPEDQSVL
                     RASNQGEPVILDINADAGKAYADTVERLLGEERPFRFIEEEKKGFLKRLFGG"
     gene            complement(3434..4129)
                     /gene="minC"
                     /locus_tag="RHX21_004265"
     CDS             complement(3434..4129)
                     /gene="minC"
                     /locus_tag="RHX21_004265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HDV1989364.1"
                     /translation="MSNTPIELKGSSFTLSVVHLHEAEPKVIHQALEDKIAQAPAFLK
                     HAPVVLNVSALEDPVNWSAMHKAVSATGLRVIGVSGCKDAQLKAEIEKMGLPILTEGK
                     EKAPRPAPAPQAPAQNTTPVTKTRLIDTPVRSGQRIYAPQCDLIVTSHVSAGAELIAD
                     GNIHVYGMMRGRALAGASGDRETQIFCTNLMAELVSIAGEYWLSDQIPAEFYGKAARL
                     QLVENALTVQPLN"
     gene            4649..5017
                     /locus_tag="RHX21_004266"
     CDS             4649..5017
                     /locus_tag="RHX21_004266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989365.1"
                     /translation="MNMMRIFYIGLSGVGMMFSSMASGHDAGGLQSPACGVVCDPYIC
                     VNSDGISPELTRKYLGEKAAENLQSLQGYDPSEFTFANGVFCDVKEKLCRDDRYFGVD
                     GKRSGKINQITTKMLFMCRE"
     gene            complement(5137..5538)
                     /locus_tag="RHX21_004267"
     CDS             complement(5137..5538)
                     /locus_tag="RHX21_004267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PPC domain-containing protein"
                     /protein_id="HDV1989366.1"
                     /translation="MKIKSISKAVLLLALLTSTSFAAGKNVNVEFSKGHSSAQYSGEI
                     KGYDYDTYTFYAKKGQKVHVSISNEGADTYLFGPGIDDSVDLSRYSPELDSHGQYSLP
                     ASGKYELRVLQTRNDARKNKTKKYNVDIQIK"
     gene            5780..6073
                     /locus_tag="RHX21_004268"
     CDS             5780..6073
                     /locus_tag="RHX21_004268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309701.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgL domain-containing protein"
                     /protein_id="HDV1989367.1"
                     /translation="MFCVIYRSSKRDQTYLYVEKKDDFSRVPEELMKGFGQPQLAMIL
                     PLDGRKKLVNADIEKVKLALTEQGYYLQLPPPPEDLLKQHLSVMGQKTDDTNK"
     gene            6145..6804
                     /locus_tag="RHX21_004269"
     CDS             6145..6804
                     /locus_tag="RHX21_004269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HDV1989368.1"
                     /translation="MYQHHNWQGALLDYPVSKVVCVGSNYAKHIKEMGSAVPEEPVLF
                     IKPETALCDLRQPLAIPSDFGSVHHEVELAVLIGATLRQATEEHVRKAIAGYGVALDL
                     TLRDVQGKMKKAGQPWEKAKAFDNSCPLSGFIPAAEFTGDPQNTTLGLSVNGEQRQQG
                     TTADMIHKIVPLIAYMSKFFTLKAGDVVLTGTPDGVGPLQSGDELTVTFDGHSLTTRV
                     L"
     gene            6896..7342
                     /locus_tag="RHX21_004270"
     CDS             6896..7342
                     /locus_tag="RHX21_004270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309703.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgN family cysteine cluster protein"
                     /protein_id="HDV1989369.1"
                     /translation="MSDVPFWQSKTLDEMSDAEWESLCDGCGQCCLHKLMDEDTDEIY
                     FTNVACRQLNIKTCQCRNYERRFEFEPDCIKLTRENLPTFEWLPMTCAYRLLAEGKDL
                     PAWHPLLTGSKAAMHGERISVRHIAVKESEVIDWQDHILNKPDWAQ"
     gene            complement(7549..>8433)
                     /gene="hlyE"
                     /locus_tag="RHX21_004271"
     CDS             complement(7549..>8433)
                     /gene="hlyE"
                     /locus_tag="RHX21_004271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415700.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin HlyE"
                     /protein_id="HDV1989370.1"
                     /translation="VEVVKNAIETADGALDLYNKYLDQVIPWQTFDETIKELSRFKQE
                     YSQAASVLVGDIKTLLMDSQDKYFEATQTVYEWCGVATQLLAAYIFLFDEYNEKKASA
                     QKDILIKVLDDGITKLNEAQKSLLVSSQSFNNASGKLLALDSQLTNDFSEKSSYFQSQ
                     VDKIRKEAYAGAAAGVVAGPFGLIISYSIAAGVVEGKLIPELKNKLKSVQSFFTTLSN
                     TVKQANKDIDAAKLKLTTEIAAIGEIKTETETTRFYVDYDDLMLSLLKEAAKKMINTC
                     NEYQKRHGKKTLFEVPEV"
BASE COUNT         2168 a         1874 c         1982 g         2409 t
ORIGIN      
        1 cccgacttgg tttccgcacc tttattcgta ctcaggagaa aaacagcggt tcgcacggtg
       61 acgactttga accttttgtt gaaatgaact ggatccataa cagtaaagat tttgctgtct
      121 caatgaacgg tgtgaaagtc gaacaagatg gggcgagtaa tttgggggaa attaaacttg
      181 gcgtaaatgg caacctgaat ccagcggcca gcgtctgggg gaatgtgggc gtgcagctgg
      241 gtgataatgg ctacaatgac accgcagtga tggtgggcct gaaatataag ttctgatccc
      301 gccgttagct aaaaaaccgc gtcgtattca tcgacgcggt acatatgaaa tattattttt
      361 tgccgatagc acgcatggtg tcatcaattg ccgtgatcaa cagcatttgc gggtctttag
      421 cgcaaacctg attcagtttt tctaccactt tggcgctcag ttccggagat tgctcaattt
      481 ttaaatcacg gctggcaacg ctggcattac ccattaccgc aacaatttct gcaacctgtg
      541 cgctgtcagt ttttgccatt tcgttggctt ctgcgcaagt aatataggtt tctgacggca
      601 aaccgttttt aatattgtag tcctgcgccc aggtcattgg tgcgaaaaca aacaggcccg
      661 ccagtaaagc aaattttttc atcatcattc cttatttcat tttacccaga attgcaccac
      721 ccgtaccgcc aatcacggca cctttaatcg ccccttcgag gccattgccg gtcagaacgc
      781 cagtgacagc accaacggcg gcacccactt ttgcaccttt acgcgcattt ttaccgtcgc
      841 ggcctttttc tgttactgca ccaacaccag cgccaacagc tgcacctttc agtacgccat
      901 taacaccatt gccagtaagt aaaccaacgc ctgcgcctag caatgcacct ttcgtggtgc
      961 ggttcatatc cgccatcgct ggcgtggagc agaacaatgc tgagataagc ccgaaggcaa
     1021 gtattttttt cttcaactta gatgtccggt attaagtaag ttgcacacac aataatttcg
     1081 tcttcaatta agatctgctt aactaaagaa cgctcgctat tattcagata attcaaaatg
     1141 agcgtggctg tgatgatagg aattatgttt tttacgtgaa tgagaataat cttaaatgag
     1201 gaataactca ttgattgaca atatttttat tcaagaagtg tcattgactg ttaacgcaat
     1261 gttgtaaagg taagataatc tgatttatca atattattgt gtgattttta tgtgagcaga
     1321 agatattcat cagcaacgat tacattagtc attttatttt gccgacggcc tcattgtcga
     1381 aagataagcg tacgacagta ttatctgaaa agagtgattt tttatccaac tacacttcag
     1441 cgcactgcgt gtaaaaaatg cctctttctt atgcgggata tcatcatttc atcatgatgt
     1501 ctttggtgag cggtgaacac aatacacctg cgctgtctct tcaggatgaa tcccctggtc
     1561 tggtgcctgc gggctgatgt tgcagcagag cttaggtcac ttagacgcta ctatcattta
     1621 tccaatggca tggaatcgaa atcagtcgat acccgcagta tatatcgtga actgggtgca
     1681 acgctgagtt acaacatgcg tctggggaac ggtatggaaa ttgaaccctg cctgaaggcg
     1741 gctgtgcgca aagaatttgt cgatgataat cgggtgaaag tgaatagtga cggtaatttt
     1801 gtcaatgatt tgtcgggcag acgtggaata taccaggcag gtattaaagc ctcattcagc
     1861 agtacgttaa gcgggcattt cggggtgggg tatagccatg gtgccggtgt ggagtccccg
     1921 tggaacgcgg tggctggtgt gaactggtcg ttctgaccat caacgattaa actgcgcttc
     1981 ggcgcagttt tcgtttacag ggggctaaaa gggaaaattc tggggcaaaa aaagcccgcc
     2041 agttacggcg ggaaacctca tcctatggga gaacaatgaa taatgaaatt gcggggttat
     2101 catcccccag tgtatccaca ctaacaatga ggttatttac tcaaccaggc ataaacattt
     2161 tgttctgtgc gtgggaacag ccttaaggtg taaaggggga ggtggaaata gcaatgagga
     2221 gtatcagcaa gaatactcgc cgctttacca caacgtggat gagagggatg aaaaactcaa
     2281 ggcagaaatg actctgcctt gaagataaat gcgtttttac agcgggctta tttcagctct
     2341 tctgcttccg gtaaggtcac gttcagctca agaatagaaa tatcgccatc tttttgctca
     2401 agctgtacgg ttaccatctc aggatcaatt tgtacgtatt tacaaatgac ctcaagaata
     2461 tctttacgca actgcggcag ataatgcggt tctgcatcgc tgcgacggcg ttcagcaaca
     2521 ataatctgca gccgttcttt tgcaatgttg gctgtgtttt tcttccgcga gagaaagaaa
     2581 tcgagtaatg ccataactta tcctccgaac aagcgtttga ggaagccttt cttctcttct
     2641 tcaatgaagc ggaaaggacg ttcttctccc aacagacgtt ctacggtatc tgcgtaggct
     2701 ttacccgcat cggcgttaat gtcgagaatg accggttcac cctggttaga ggcgcgcaat
     2761 actgattgat cctctgggat cacgccgacg agtttgatgc gcaggatctc cagcacatct
     2821 tccatgctca gcatgtcacc tctgcttacg cggcctgggt tatagcgcgt taacagcagg
     2881 tgctctttaa taggctcttc gccattttct gcgcggcgtg atttcgacgc cagaatgcct
     2941 aaaatacggt cagagtcgcg tactgaggag acttccgggt tggtggtaat aatggcttcg
     3001 tctgcaaaat agagtgccat taacgcaccg gtttcaatcc ctgccgggga gtcacaaacg
     3061 ataaattcaa aatccatcgc tttcagatca tcaagaactt tggcgacccc ttcacgggtg
     3121 agggcatctt tatcgcgtgt ttgcgatgcc ggaagaatat agagattttc agtacgctta
     3181 tctttaatta acgcctgatt tagcgttgca tcgccctgaa tgacgttgac gaaatcgtaa
     3241 acgacccggc gttcgcaacc cataatcagg tcgagattac gcaggccgat atcaaaatct
     3301 atcacgacag ttttctttcc cttctgggcc aaaccagtgg cgatggccgc gctggaggtt
     3361 gtcttaccaa cacccccttt gcccgaagta acaacaataa tgcgtgccat agaaattcct
     3421 tgttaaaaag ggatcaattt aacggttgaa cggtcaaagc gttttcgact aactgcagtc
     3481 gcgccgcttt gccataaaat tctgctggga tttgatcact cagccagtat tcacctgcga
     3541 tggacaccag ttccgccatc aggttcgtac aaaatatttg cgtttcccgg tcaccacttg
     3601 cccctgcaag cgcacgaccg cgcatcatgc catagacatg aatgttccca tcggcaatca
     3661 attcggcccc agcgctaacg tggcttgtaa caatcagatc acattgtgga gcataaatac
     3721 gctgaccgga acgcaccggg gtatctatta aacgcgtttt tgtgaccggc gttgtatttt
     3781 gcgctggagc ctgtggtgcg ggagctggac gcggcgcttt ttcctttcct tccgtcagga
     3841 taggcagccc catcttttca atttcggctt taagttgcgc atctttgcag ccacttacgc
     3901 caataacccg caaaccggtt gccgaaaccg ccttatgcat cgctgaccag tttaccgggt
     3961 cttccagtgc actgacgttg agtacaacgg gggcatgttt taaaaatgcg ggggcctgag
     4021 cgattttgtc ttccagcgcc tgatggataa ccttaggttc tgcctcatgc agatgaacca
     4081 cagataaagt gaagctactg cctttaagct cgattggcgt gtttgacatc ctggccttac
     4141 tcaattagct attaatcatc gccagcgcgc gatgatgttc cgaagactat aaggcatgtt
     4201 atagtctgga ttatattgag gcaagtcacc ctcccattta ttcagagtaa aagtctattc
     4261 tgtgataaat ggcgctgatt catagcttaa aaaataccct tgtcaatcaa cccattgccg
     4321 tcgtactttt gattgttctt atttacgctt cctttttccg caccctaatc gtgacagcat
     4381 ctccagacct gtttaaatat ccagtattga ggcaagtgta ttttttcacc acgccaggct
     4441 ttcttaactt tccatttttt gcggcatcat taaagaacag atacccgtta tcttaatatc
     4501 cgccacagaa ttgctctatc atagaaaccg cagaagacgt ctgatacttc tgtcaggtca
     4561 tcgtaactcg tccaggtcag cggttttgat tacggattga tgatgaaatg agcataagtg
     4621 ttgtacggtt ggattatcag gatgtgctat gaatatgatg cgtatttttt atatcggatt
     4681 gtcaggtgtg gggatgatgt tctcatcaat ggcgtctgga catgacgctg gcggacttca
     4741 atctccggcg tgcggcgttg tttgcgaccc gtatatttgt gtgaactcag atggtatttc
     4801 cccagagtta acaaggaaat atctcggcga aaaagccgct gaaaacttac aatcattaca
     4861 aggctacgat cccagcgaat ttacattcgc taacggtgta ttttgcgatg ttaaagaaaa
     4921 attatgtcgt gatgatcgtt attttggtgt ggatggtaag cggagtggaa aaatcaatca
     4981 aatcaccaca aagatgttat ttatgtgtcg tgagtgatgc cttgtttaca ttatgttcta
     5041 ttcggcattg tctgctattc gtcattaacc tcttgagcga cagagaggag tggggcgtta
     5101 acgtttatga cggggagagt ccccgtcggt tgacatttac ttaatttgaa tatcgacgtt
     5161 atatttttta gttttgtttt tacgggcgtc gtttcgggtt tgcagcactc gcagctcata
     5221 tttgccagaa gcagggagtg agtattgtcc gtgactatcg agttctggtg aatatctgga
     5281 taaatcaact gaatcatcga ttcctggccc gaagaggtaa gtatcagcgc cttcattaga
     5341 gatactcaca tgcactttct gacctttttt ggcatagaag gtatatgtat cgtaatcgta
     5401 tccctttatt tcgccggagt actgagcgct gctatggcct ttgctgaact caacattgac
     5461 attcttaccc gcagcaaagc tcgtggaggt tagcagtgca agcagcaata cagccttact
     5521 gatgctcttg attttcattg gtagtctcct gttcagaatg agtacgatga actgttataa
     5581 tataacaatt ccttacggga gaattccagt ggcttttctg cgttcggtaa aatcccggcg
     5641 cggcattttt tgccgggggg attacttata aaggggcatg gactcaacaa accgcagaaa
     5701 tctacagctg gctggcttgt ggcgcgggtt tcattgatgt tagcttatgc caaaacctgg
     5761 catcttaaag agtaaaagta tgttttgtgt gatttatcga agcagcaagc gtgaccagac
     5821 ctatttatat gtcgaaaaaa aagacgattt ttcgcgtgtt cctgaggaac tgatgaaagg
     5881 ttttggtcag cctcagttag cgatgattct gccgctggat gggcgcaaga aactggtcaa
     5941 tgctgatatt gaaaaggtta aactggcatt aaccgagcaa ggttactatt tgcagttacc
     6001 gccaccaccc gaagatttgc tgaagcaaca tctttccgtc atggggcaga aaacagacga
     6061 cactaacaaa taaccgatat ccggcggtgg cattatcttt gtcggcgcgg gttttcatat
     6121 ccacgataag gtgaggggaa cgttatgtat caacatcata actggcaagg tgcgctgctg
     6181 gattatccgg tgagtaaagt agtctgtgtt ggcagtaact atgccaaaca tattaaagag
     6241 atgggcagcg cagtgcccga agagccagtg ctgtttatta aaccagaaac ggcactgtgc
     6301 gatctgcggc agccattggc gatcccatcc gatttcggtt cagttcatca tgaagtcgaa
     6361 ctggcggtgt tgattggcgc gacgctgcgt caggcaacgg aagagcatgt ccgcaaagcc
     6421 attgccggtt acggcgtggc gcttgatctg acattgcgtg atgttcaggg aaaaatgaag
     6481 aaagccgggc agccgtggga aaaggctaaa gcgtttgata actcttgtcc gctttccggg
     6541 tttatccccg cggcggaatt taccggcgat ccacaaaata caacgctggg cctgagcgta
     6601 aacggcgaac aacgccagca aggtacgact gcggacatga tccataaaat cgttccgttg
     6661 atcgcttata tgagcaagtt ttttaccctc aaggccggtg acgttgtgtt gacaggcacg
     6721 cctgatggcg tcggcccgtt gcaaagcggt gatgagctga cagtcacttt cgatgggcat
     6781 tctttgacaa ctcgcgtttt gtaatacttt ttgccgcctg aaagcggcgg caaaacttgc
     6841 atcgctgtgc cagactggtt ataaggtgcg ttttaacgta atggcggaac acctgatgag
     6901 cgatgtacct ttctggcaaa gtaaaaccct ggacgaaatg agcgatgcgg aatgggagtc
     6961 gttgtgtgat ggttgcggtc agtgttgcct gcataaactg atggatgaag acaccgacga
     7021 aatctacttc actaacgtcg cctgtcgcca gctcaatatt aaaacttgtc aatgtcggaa
     7081 ctacgaacgt cgtttcgagt ttgaacccga ctgcattaaa ttaacccgtg aaaatctgcc
     7141 aacattcgaa tggctgccaa tgacctgcgc ttatcgtttg ctggcggaag gtaaagattt
     7201 acctgcgtgg catccgctac ttactggttc gaaagcggca atgcatggtg aacgtatctc
     7261 tgtgcgtcat atcgcagtga aagaatcaga agtgattgac tggcaggatc atatcttaaa
     7321 taaacctgac tgggcgcagt gataaattta atagatgttg atgggggctt tcttaatata
     7381 cgtctggatg ctcgccattt cgtagccctg tttttgaaag cgctctgtca taatgagagt
     7441 tacccgatac cttattatca acaggtaact ctcaatcttt aaaaaacgtc tgtgttttta
     7501 aatgtgataa accttatacc ttgagtacat ggagagaata atcgcttatc agacttcagg
     7561 tacctcaaag agtgtctttt taccgtgtct tttctgatac tcattacagg tgttaatcat
     7621 ttttttggcc gcttctttta gcaaagaaag cattaaatca tcataatcaa catagaatct
     7681 ggttgtttca gtttccgttt ttatctcccc gatggcggct atttcggtgg ttaatttcaa
     7741 tttggcggca tcgatatctt tattcgcttg tttaaccgtg ttagacaggg tggtaaagaa
     7801 actctgcaca gattttaact tgttcttcaa ttctgggatc agtttccctt caactacgcc
     7861 cgcagcaata gaataggaaa tgattaatcc aaatggaccg gcgacgacac cggctgcggc
     7921 accggcatac gcttccttcc tgattttatc tacctgtgac tggaaatagc tgcttttttc
     7981 tgaaaaatca ttggttaact ggctatctaa cgccagcagt ttcccggaag cgttgttgaa
     8041 actttgtgag cttaccagca gggatttttg cgcttcattc agcttcgtga tgccgtcatc
     8101 cagtacctta atgagaatgt ctttctgggc ggatgctttc ttctcattgt actcatcaaa
     8161 tagaaaaata tacgctgcga gcaattgcgt cgcaacacca caccattcat acactgtttg
     8221 ggttgcttca aaatacttat cctggctatc cataagtaag gttttaatat cgccgactaa
     8281 aacggaggct gcctgtgaat actcctgttt aaagcgactt aactctttta tggtttcatc
     8341 aaaggtctgc caggggatga cctgatcgag atatttatta taaagatcta atgctccatc
     8401 tgcagtttcg attgcgtttt taactacttc tac
//
LOCUS       DAPGUL010000164         8419 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.167, whole genome shotgun sequence.
ACCESSION   DAPGUL010000164 DAPGUL010000000
VERSION     DAPGUL010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8419)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8419)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8419
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.167"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            10..303
                     /locus_tag="RHX21_004272"
     CDS             10..303
                     /locus_tag="RHX21_004272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000070395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system YeeU family
                     antitoxin"
                     /protein_id="HDV1989371.1"
                     /translation="MTPCFGARLVQEGNRLHYLADRAGIRGLFSDADAYHLDQAFPLL
                     MKQLELMLTSGELNPRHQHTVTLYAKGLTCKADTLSSCGYVYLAVYPTPEMKN"
     gene            392..765
                     /gene="cbtA"
                     /locus_tag="RHX21_004273"
                     /pseudo
     CDS             392..765
                     /gene="cbtA"
                     /locus_tag="RHX21_004273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system toxin CbtA"
     gene            762..956
                     /locus_tag="RHX21_004274"
     CDS             762..956
                     /locus_tag="RHX21_004274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310834.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989372.1"
                     /translation="MMTLEADSVNVQALDMGHIVVDIDGVNITELINKAAENGYSLRV
                     VDDRDSTETPATYASPHQLL"
     gene            969..1082
                     /locus_tag="RHX21_004275"
     CDS             969..1082
                     /locus_tag="RHX21_004275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001161660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF957 domain-containing protein"
                     /protein_id="HDV1989373.1"
                     /translation="MQGIVPLTTETALLSCIKQAREDVLTLRHLQLLHQNR"
     gene            complement(1371..1517)
                     /locus_tag="RHX21_004276"
                     /pseudo
     CDS             complement(1371..1517)
                     /locus_tag="RHX21_004276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080164.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
     gene            1571..1753
                     /locus_tag="RHX21_004277"
     CDS             1571..1753
                     /locus_tag="RHX21_004277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein"
                     /protein_id="HDV1989374.1"
                     /translation="MNHPVIGVVTKADLASMEQISLVKSWLREAGAHNVLVTSAVNNN
                     GVTELFALLHTEEGCC"
     gene            complement(1854..2183)
                     /locus_tag="RHX21_004278"
     CDS             complement(1854..2183)
                     /locus_tag="RHX21_004278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310836.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF496 family protein"
                     /protein_id="HDV1989375.1"
                     /translation="METTKPSFQDVLEFVRLFRRKNKLQREIQDVEKKIRDNQKRVLL
                     LDNLSDYIKPGMSVEAIQGIIASMKGDYEDRVDDYIIKNAELSKERRDISKKLKAMGE
                     MKNGEAK"
     gene            complement(2355..3413)
                     /locus_tag="RHX21_004279"
     CDS             complement(2355..3413)
                     /locus_tag="RHX21_004279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDV1989376.1"
                     /translation="MRADKSLSPFEIRVYRHYRIVHGTRVALAFLLTFLIIRLFTIPE
                     STWPLVTMVVIMGPISFWGNVVPRAFERIGGTVLGSILGLIALQLELISLPLMLVWCA
                     AAMFLCGWLALGKKPYQGLLIGVTLAIVVGSPTGEIDTALWRSGDVILGSLLAMLFTG
                     IWPQRAFIHWRIQLAKSLTEYNRVYQSAFSPNLLERPRLESHLQKLLTDAVKMRGLIA
                     PASKETRIPKSIYEGIQTINRNLVCMLELQINAYWATRPSHFVLLNAQKLRDTQHMMQ
                     QILLSLVHALYEGNPQPVFANTEKLNDAVEELRQLLDNHHDLKVVETPIYGYVWLNME
                     TAHQLELLSNLICRALRK"
     gene            complement(3611..4084)
                     /gene="sbmC"
                     /locus_tag="RHX21_004280"
     CDS             complement(3611..4084)
                     /gene="sbmC"
                     /locus_tag="RHX21_004280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor SbmC"
                     /protein_id="HDV1989377.1"
                     /translation="MNYEIKQEEKRTVAGFHLVGPWEQTVKKGFEQLMMWVDSKNIVP
                     KEWVAVYYDNPDETPAEKLRCDTVVTVPNNFTLPENSEGVILTEISGGQYAVAVARVV
                     GDDFAKPWYQFFNSLLQDSAYEMLPKPCFEVYLNNGAEDGYWDIEMYVAVQPKHH"
     gene            complement(4203..5369)
                     /gene="dacD"
                     /locus_tag="RHX21_004281"
     CDS             complement(4203..5369)
                     /gene="dacD"
                     /locus_tag="RHX21_004281"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416514.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase DacD"
                     /protein_id="HDV1989378.1"
                     /translation="MKRRLIIAASLFIFNLSSGFAAENIPFSPQPPQIHAGSWVLMDY
                     TTGQILTAGNEHQQRNPASLTKLMTGYVVDRAIDSHRITPDDIVTVGRDAWAKDNPVF
                     VGSSLMFLKEGDRVSVRDLSRGLIVDSGNDACVALADYIAGGQRQFVEMMNNYAEKLH
                     LKDTHFETVHGLDAPGQHSSAYDLAVLSRAIIHGEPEFYHMYSEKSLTWNGITQQNRN
                     GLLWDKTMNVDGLKTGHTSGAGFNLIASAVDGQRRLIAVVMGADSAKGREEEARKLLR
                     WGQQNFTTVQILHRGKKVGTERIWYGDKENIDLGTEQEFWMVLPKAEIPHIKAKYTLD
                     GKELTAPISAHQRVGEIELYDRDKQVAHWPLVTLESVGEGSMFSRLSDYFHHKA"
     gene            5578..7005
                     /gene="sbcB"
                     /locus_tag="RHX21_004282"
     CDS             5578..7005
                     /gene="sbcB"
                     /locus_tag="RHX21_004282"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease I"
                     /protein_id="HDV1989379.1"
                     /translation="MMNDGKQQSTFLFHDYETFGTHPALDRPAQFAAIRTDDEFNVIG
                     EPEVFYCKPADDYLPQPGAVLITGITPQEARAKGENEAAFAARIHSLFTVPKTCILGY
                     NNVRFDDEVTRNVFYRNFYDPYAWSWQHDNSRWDLLDVMRACYALRPEGINWPENDDG
                     LPSFRLEHLTKANGIEHSNAHDAMADVYATIAMAKLVKTRQPRLFDYLFTHRNKHKLM
                     ALIDVPQMKPLVHVSGMFGAWRGNTSWVAPLAWHPENRNAVIMVDLAGDISPLLELDS
                     DTLRERLYTAKADLGDNAAVPVKLVHINKCPVLAQANTLRPEDADRLGINRQHCLDNL
                     KILRENPQVREKVVAIFVEAEPFTPSDNVDAQLYNGFFSDADRAAMKIVLETEPRNLP
                     ALDITFVDKRIEKLLFNYRARNFPGTLDYAEQQRWLEHRRQVFTPEFLQGYAEEIQML
                     AQQYADDKEKVALLKALWQYAEEIV"
     gene            complement(7048..7275)
                     /locus_tag="RHX21_004283"
     CDS             complement(7048..7275)
                     /locus_tag="RHX21_004283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA family protein"
                     /protein_id="HDV1989380.1"
                     /translation="MAIKKLDVVTQVCPFPLIEAKAALAEMASGDELVIEFDCTQATE
                     AIPQWAAEEGHAITDYQQIGDAAWSITVQKA"
     gene            complement(7289..8347)
                     /gene="yeeE"
                     /locus_tag="RHX21_004284"
     CDS             complement(7289..8347)
                     /gene="yeeE"
                     /locus_tag="RHX21_004284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transport protein YeeE"
                     /protein_id="HDV1989381.1"
                     /translation="MFSMILSGLICGALLGFVMQRGRFCLTGGFRDMYIAKNNRMFYA
                     LLIAISVQSVGVFALIQAGLLTYEAGAFPWLGTVIGGYLFGLGIVLAGGCATGTWYRA
                     GEGLIGSWIALFTYMVVSAVMRSPHASGLNQTLQHYTTEHNSIADTFNLSVWPLVAVL
                     LVITLWVVMKELKKPKLKVATLPPRRTGIAHILFEKRWHPFVTAVLIGLIALLAWPLS
                     EATGRMFGLGITSPTANILQFLVAGDVKYINWGVFLVLGIFVGSFIAAKASREFRVRA
                     ADAQTTLRSGLGGVLMGFGASIAGGCSIGNGLVMTAMMTWQGWIGLVFMILGVWTASW
                     LVYVRPQRKARLATAAAN"
BASE COUNT         2249 a         2172 c         1956 g         2042 t
ORIGIN      
        1 ccctgcaccg tgacgccctg tttcggggca cgtctggtgc aggagggtaa ccggttgcat
       61 taccttgccg accgcgccgg tatcagaggc ctgttcagcg atgcagatgc gtaccacctg
      121 gaccaggcct ttccgctgct gatgaaacaa ctggaactca tgctcaccag cggtgaactg
      181 aatccccgcc atcagcatac cgtcacgctg tatgcaaaag ggctgacctg caaagccgat
      241 accctcagca gttgtggtta cgtttatctg gctgtttatc cgacgcccga aatgaaaaat
      301 taactctcca gaatagcctt ctgctacggc ctggtgtttt caccacgcca cttttccatt
      361 tttatatctg catatcagga aaatcttcag tatgaaaaca ttacctgtat tacccgggca
      421 ggcggccagt tctcgcccgt ctcctgttga aatctggcag atactgctgt cccgactgct
      481 ggaccagcac tatggcctca cactgaatga cacacctttt gccgatgaac gtgtgattga
      541 gcagcatatt gaggcaggca tttcactgtg tgatgcggtg aactttctcg tggaaaaata
      601 cgcgctggtg ctaccgacca gccgggattc agcgcctgta cccgctctca gttaataaac
      661 agcatcgata tcctccgggc tcgcagggcg accggcctga tgacccgcga caattacaga
      721 acggtaaata acattaccct gggtaagtat ccggaggcga aatgatgaca ctggaagccg
      781 acagcgttaa cgtacaggcg ctggatatgg ggcacattgt cgttgacatt gatggtgtta
      841 atatcactga actgattaat aaggccgctg aaaacggtta ttcactccgc gtggtggatg
      901 accgtgactc taccgaaaca ccggcaactt atgccagccc tcaccagttg ctgtaagaca
      961 atgcagtgat gcagggtata gtgccattaa ccacagaaac agcactgttg tcctgtatta
     1021 agcaggcaag agaagatgtc cttaccctgc gccatctgca gcttctgcac cagaaccggt
     1081 gaatctcact caacaggctt catttcccct gacgccagcc tgaatacagc tggcgttttc
     1141 atttataaac agaaaggaaa accgataata atggaatgga cgccccgacc atgaagcaac
     1201 ggtaggatat tactgataaa ccttccagtg gaggtgcgtt atggccgttt taacgattag
     1261 cattgacctg acaaaaaatg aattccaaat ccacggtctg ggtaggaaca gaaaaatcta
     1321 agctcagaaa acggattaaa gtaagcgtca acggagcacc gtattgacgc ttatttattg
     1381 gtgagaacta cgttccatgg caggagttcg tcaacacggt tggagggcca ttccggcagt
     1441 atgctcagaa tatggcgcag atacgcttcc ggatcgatac cgttcagacg gcaggtgcct
     1501 gcttttccgg caacaagcag gaatctcagc gctgaagcag gaattagagg taaaaacgcc
     1561 ctaccgggcc atgaatcacc cggtcattgg agtagtaacc aaagcagatt tagccagcat
     1621 ggaacaaata tctttggtga aaagttggtt acgggaagct ggagcgcaca acgtgttagt
     1681 aaccagtgca gttaataaca atggagttac agaacttttt gccttgctgc atacagaaga
     1741 aggctgttgt taatttcgat tggttctcag atgagaatga tgacggtgat acacagataa
     1801 gaatcaatga gcaatgaggg ttaccgggca accctcattg aataaaacgg gaattacttc
     1861 gcttcgccgt ttttcatttc gcccatagct ttcagctttt tggagatatc gcggcgttct
     1921 ttggagagct cggcattttt gatgatgtaa tcgtcaacgc gatcttcata gtcacctttc
     1981 atgctggcga tgatgccctg gattgcttca acgctcatcc ctggcttgat gtaatcgctc
     2041 aggttgtcca gcaacaggac gcgcttctgg ttgtcacgga tctttttctc aacgtcctga
     2101 atttcacgtt gcagtttgtt cttacgacgg aacagacgaa caaattctag tacgtcctgg
     2161 aatgaaggct tggtagtttc catttttata cccctgataa tgtgagagtc ggattcgttt
     2221 aagcaaccgc tattcgttag ggccaacatt actcatagct gccgcagatg acaatgcttt
     2281 tatccctttt cactatcata ccctttatcc ttgctgaatc gaagcagcag caagatgatt
     2341 ctgaagttca ggaattattt gcgcaaggcc cggcaaatca gattcgatag caactcaagc
     2401 tgatgtgccg tttccatgtt cagccacaca taaccataga ttggtgtttc cacaaccttc
     2461 aggtcatggt ggttatcgag caactgacgc agctcttcca cagcatcgtt caatttttcc
     2521 gtattggcaa aaaccggctg cggattacct tcgtacagcg catgaacaag gctcagcagt
     2581 atttgctgca tcatgtgctg ggtatcacga agtttttgcg cgttcaataa cacgaaatgg
     2641 ctggggcgcg tggcccagta cgcattgatt tgcaactcca gcatacaaac cagattgcgg
     2701 ttaatggtct ggataccttc atatatcgat ttgggaatac gggtttcttt gctggcgggc
     2761 gcaatcagcc cacgcatttt cacggcatcg gtcagcagtt tttgtagatg gctttccaga
     2821 cgtgggcgtt cgagtaagtt cggtgagaat gcagattgat agacccgatt atactcggtc
     2881 agacttttcg ccagttgaat gcgccagtgg atgaacgccc gttgtggcca gataccggta
     2941 aacaacattg ccagtaaaga gccgaggatc acatcgccgc ttcgccataa cgccgtatca
     3001 atttcacctg tcggggaacc cacaacaatt gccagcgtca ccccaatcaa taatccttga
     3061 tacggtttct tgcccagcgc cagccaaccg caaagaaaca tcgccgccgc gcaccagact
     3121 aacatcagcg gtaacgaaat taactccagt tgcagagcga taagacctaa aatcgacccc
     3181 aacaccgtac cgccaatacg ttcgaaggca cgagggacaa cgttccccca gaacgagatt
     3241 ggccccataa tcaccaccat ggtgaccagc ggccaggtgc tttccgggat agtaaacagg
     3301 cggataatga gaaaagtgag caggaatgcc agcgcgaccc gagtaccatg cacaatgcgg
     3361 taatggcggt atacccggat ttcaaacggg cttaatgact tatcggcacg cactcagaaa
     3421 ctccgtaatg aagatgaaaa gcgctcataa cacatctgtc ggccagaagg cgcgcctctg
     3481 agttatccga cggacatacc gggaacagtg taatttcccg gcaggagcga aaaatttgaa
     3541 aggcgcatct tactcttttc gctttcaaaa aaagagtggt cttcgcgtta acacaccgcc
     3601 ctgagatgaa ttagtgatgt tttggctgca ccgcaacata catttcgata tcccagtacc
     3661 catcttccgc gccattgttc aagtaaacct cgaagcaggg ctttggtaac atttcataag
     3721 cactgtcctg caagaggcta ttaaagaact gataccaggg tttagcaaaa tcatcaccga
     3781 ctacacgagc caccgccacc gcatattgac cacctgaaat ttctgtcaga atgacgccct
     3841 cactgttttc ggggagcgta aagttattcg gtaccgtcac gacggtgtcg cagcgtaatt
     3901 tttcggcggg tgtttcatcc ggattgtcgt aatagacagc aacccactcc ttcggcacaa
     3961 tatttttgct atctacccac atcatcaact gctcaaaacc tttctttacc gtctgttccc
     4021 acgggccaac gagatggaaa cctgcaacgg tacgtttctc ttcctgctta atctcgtagt
     4081 tcatgacgcc tccattgatg ctgtttttat atacagtata gttgcaaaat taaaaccaca
     4141 aggaatgagt gttgattatg cgagcagact cgcactcctg ccagtctgct gcaaaagaaa
     4201 ggtcaggcct tatggtggaa ataatcactc aggcgagaaa acatgctgcc ttccccgaca
     4261 gattccaggg taaccagcgg ccagtgcgcc acctgtttat cacggtcgta aagttcaatt
     4321 tcccctaccc gctgatgggc gctaattggc gcggtgagct ctttaccatc aagggtatat
     4381 ttggctttga tatgtggaat ttcggctttc ggtagcacca tccagaactc ttgttccgtt
     4441 cccaggtcga tattttcttt atcgccatac cagatgcgtt ccgttccgac ctttttccca
     4501 cggtgcaaaa tttgcaccgt agtaaagttt tgttgccccc aacgcagtaa ttttcttgcc
     4561 tcttcctcac gaccttttgc actgtcagcc cccattacca ctgcaatgag acgacgctgc
     4621 ccatctacag ccgaagcaat gagattaaac ccggcaccag aagtatgacc cgttttcagg
     4681 ccgtcaacat tcatggtttt atcccacaac aacccgttac ggttttgctg ggtgataccg
     4741 ttccaggtga gacttttctc actgtacata tgataaaact cgggctcgcc gtggatgata
     4801 gcgcgagaaa gcacagctaa atcataagcc gagctatgct ggccaggtgc atccagacca
     4861 tgcactgttt caaaatgcgt atccttgaga tgcagcttct cggcatagtt gttcatcatt
     4921 tcaacaaact gccgttgccc accggcaata tagtcagcca gagcaacaca agcgtcattt
     4981 ccggaatcca caattaaacc acggcttaaa tcacgtaccg atacgcgatc gccctctttc
     5041 aaaaacatca gtgaagaacc gacaaacacc ggattatctt tcgcccacgc atcgcgcccc
     5101 acggtgacaa tatcgtctgg cgtaatgcga tgactatcga tagcgcgatc cacgacataa
     5161 cccgtcatca gctttgtcag gctggcggga ttgcgctgtt gatgctcatt acccgcggtg
     5221 aggatctgac cggtggtgta atccatcagt acccaggacc cggcatgaat ctgtggaggc
     5281 tgaggtgaaa aaggaatgtt ttccgccgca aaaccagacg ataagttaaa aatgaacaaa
     5341 gaagcagcaa taataagacg gcgtttcaac agcaaaccct caggagtttc aaatagctgt
     5401 tctttttacg gaaatactta tgaactggct ggaataaagt gcaagaaaat gtgactaccc
     5461 tctcattttt atctgacatg atctgttgtc actcgctgtc aaattgtcgc gctaaagctg
     5521 attagcacgg tgatatttga tactctggca gacagcagaa ataacggatt taacctaatg
     5581 atgaatgacg gtaagcaaca atctaccttt ttgtttcacg attacgaaac ctttggcacg
     5641 caccccgcgt tagatcgccc tgcacagttc gcagccattc gcaccgatga cgaattcaat
     5701 gtcatcggcg aacccgaagt cttttactgc aagcccgcgg atgactattt accccagcct
     5761 ggagcagtat taattaccgg tattaccccg caggaggcac gagcgaaagg agaaaacgaa
     5821 gccgcgtttg ccgcccgtat tcactcgctt tttaccgtac cgaagacctg tattctgggc
     5881 tacaacaatg tgcgtttcga cgacgaagtc acacgcaacg ttttttatcg taatttctac
     5941 gatccttacg cctggagctg gcagcatgat aactcgcgct gggatttact ggatgttatg
     6001 cgtgcctgtt atgccctgcg cccggaagga ataaattggc ctgaaaatga tgacggtcta
     6061 ccgagctttc gccttgagca tttaaccaaa gcgaatggta ttgaacatag caacgcccac
     6121 gatgcgatgg ctgatgtgta cgccactatt gcgatggcaa aactggtaaa aacgcgtcag
     6181 ccacgcctgt ttgattatct ctttacccat cgtaataaac acaaactaat ggcgttgatt
     6241 gatgttcctc agatgaaacc cctggttcac gtttccggaa tgtttggggc atggcgcggc
     6301 aatacaagct gggtggcacc gctggcgtgg catcctgaaa atcgcaatgc cgtaattatg
     6361 gtggatttgg caggagacat ttcgccatta ctggagctgg atagcgacac attgcgcgag
     6421 cgtttatata ccgcaaaagc cgatcttggc gataacgccg ccgttccggt taagctggta
     6481 catatcaata aatgtccggt actggcccag gcgaatacgc tacgcccgga agatgccgac
     6541 cgactgggaa ttaatcgtca gcattgcctc gataacctaa aaattctgcg tgaaaatccg
     6601 caagtgcgtg aaaaagtggt agcgatattc gtggaagccg aaccgtttac accttcagat
     6661 aatgtggatg cacagcttta taacggcttt ttcagtgacg ccgatcgtgc agcaatgaaa
     6721 attgtgctgg aaaccgagcc gcgtaattta ccggcactgg atatcacttt tgttgataaa
     6781 cgaattgaaa agctgttgtt caattatcgg gcgcgcaact tcccggggac gctggattat
     6841 gccgagcagc aacgctggct ggagcaccgc cgccaggtct tcacgccaga gtttttacaa
     6901 ggctatgcag aagagattca gatgctggcg cagcagtatg ccgacgataa agaaaaagtg
     6961 gcgctgttaa aagcgctttg gcagtacgcg gaagagattg tctaatgtga agcctccgcc
     7021 gctggtacgg cggaggacaa ttttgagtca ggctttttga acggtgatgc tccacgctgc
     7081 atcgccaatc tgctgataat cggtgatggc atgtccttct tctgccgccc actgtgggat
     7141 tgcttcagtt gcctgggtgc aatcaaactc aattaccaac tcatcgccgc tggccatttc
     7201 tgccagtgct gcttttgctt ctatgagtgg aaacggacag acctgcgtca ccacatccag
     7261 ctttttaatc gccatcttta caccttactt aatttgccgc agcagttgcc agtcgtgcct
     7321 tacgctgcgg tcgaacatac acaagccagg acgcagtcca gactccgaga atcataaata
     7381 caaggccaat ccagccctgc caggtcatca ttgcagtcat gaccagtcca ttaccgatag
     7441 agcaaccacc tgcaatgctg gcaccgaagc ccatcagtac accacctaac ccgctacgta
     7501 atgttgtttg tgcatcagca gcgcgaacgc ggaactcacg gctcgctttg gctgcaataa
     7561 atgaccccac gaagatccct aacaccagga aaacgcccca gttaatgtat ttcacgtcac
     7621 ccgcgaccag aaattgcaga atattggccg ttggggaagt gattcctaac ccaaacatgc
     7681 gtccggttgc ttcactcagg ggccaggcta aaagcgcaat caaaccgatg agtacagcag
     7741 tgacaaaggg atgccagcgt ttttcaaaca gaatatgagc gatcccggtt cggcgcggcg
     7801 gtaaggtcgc gactttgagt tttggcttct tcaactcttt catcaccacc cagagcgtta
     7861 tcaccagcaa aacggcaacc aacggccaca cagacaaatt aaaagtatca gcaatagagt
     7921 tatgttcagt agtgtagtgc tgcaaggttt gatttaaacc actggcgtgt ggagaacgca
     7981 tcaccgcact caccaccata taagtgaaaa gcgcgatcca actgccgatc aatccctcac
     8041 ccgcgcgata ccaggtcccg gtggcacatc cacccgccag aacaattccc agcccgaaaa
     8101 gatacccacc tataacagta ccaagccacg ggaacgcccc ggcttcgtaa gtcagtaggc
     8161 ccgcctgaat taacgcaaaa acccccacgc tttgtaccga aattgcaatc agcaaggcgt
     8221 aaaacatgcg attatttttc gcgatataca tatcgcgaaa accacctgtc aggcaaaaac
     8281 gcccacgctg catgacaaat cccagcagag caccacaaat tagcccgctt aatatcattg
     8341 aaaacataaa ttaattaacc agatgaatgt taatggggaa attattcatg actggtggaa
     8401 tgcagaccaa taaccaaat
//
LOCUS       DAPGUL010000165         8408 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.168, whole genome shotgun sequence.
ACCESSION   DAPGUL010000165 DAPGUL010000000
VERSION     DAPGUL010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8408
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.168"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(60..1652)
                     /locus_tag="RHX21_004285"
     CDS             complement(60..1652)
                     /locus_tag="RHX21_004285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATPase"
                     /protein_id="HDV1989382.1"
                     /translation="MLVSSNVTMQFGSKPLFENISVKFGGGNRYGLIGANGSGKSTFM
                     KILGGDLEPTLGNVSLDPNERIGKLRQDQFAFEEFTVLDTVIMGHKELWEVKQERDRI
                     YALPEMSEEDGYKVADLEVKYGEMDGYSAEARAGELLLGVGIPVEQHYGPMSEVAPGW
                     KLRVLLAQALFADPDILLLDEPTNNLDIDTIRWLEQVLNERDSTMIIISHDRHFLNMV
                     CTHMADLDYGELRVYPGNYDEYMTAATQARERLLADNAKKKAQIAELQSFVSRFSANA
                     SKSRQATSRARQIDKIKLEEVKASSRQNPFIRFEQDKKLFRNALEVEGLTKGFDNGPL
                     FKNLNLLLEVGEKLAVLGTNGVGKSTLLKTLVGDLQPDSGTVKWSENARIGYYAQDHE
                     YEFENDLTVFEWMSQWKQEGDDEQAVRSILGRLLFSQDDIKKPAKVLSGGEKGRMLFG
                     KLMMQKPNILIMDEPTNHLDMESIESLNMALELYQGTLIFVSHDREFVSSLATRILEI
                     TPERVIDFSGNYEDYLRSKGIE"
     gene            1871..2791
                     /gene="ldtB"
                     /locus_tag="RHX21_004286"
     CDS             1871..2791
                     /gene="ldtB"
                     /locus_tag="RHX21_004286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HDV1989383.1"
                     /translation="MNMKLKTLFAAAFAVVGFCSTASAVTYPLPTDGSRLVGQNQVIT
                     IPEGNTQPLEYFAAEYQMGLSNMMEANPGVDTFLPKGGTVLNIPQQLILPDTVHEGIV
                     INSAEMRLYYYPKGTNTVIVLPIGIGQLGKDTPINWTTKVERKKAGPTWTPTAKMHAE
                     YRAAGEPLPAVVPAGPDNPMGLYALYIGRLYAIHGTNANFGIGLRVSHGCVRLRNEDI
                     KFLFEKVPVGTRVQFIDEPVKATTEPDGSRYIEVHNPLSTTEAQFEGQEIVPITLTKS
                     VQTVTGQPDVDQVVLDEAIKNRSGMPVRLN"
     gene            complement(2850..3968)
                     /locus_tag="RHX21_004287"
     CDS             complement(2850..3968)
                     /locus_tag="RHX21_004287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion transporter"
                     /protein_id="HDV1989384.1"
                     /translation="MSLPFLRTLQGDRFFQLLILVGIGLSFFVPFAPKSWPAAIDWHT
                     IITLSGLMLLTKGVELSGYFDVLGRKMVRRFATERRLAMFMVLAAALLSTFLTNDVAL
                     FIVVPLTITLKRLCEIPVNRLIIFEALAVNAGSLLTAIGNPQNILIWGRSGLSFAGFI
                     AQMAPLAGAMMLTLLLLCWCCFPGKALQYHTGVQTPEWKPRLVWSCLGLYIVFLTALE
                     FKQELWGLVIVAAGFALLARRVVLSVDWTLLLVFMAMFIDVHLLTQLPALQGVLGNVS
                     HLSEPGLWLTAIGLSQVISNVPSTILLLNYVPPSLLLVWAVNVGGFGLLPGSLANLIA
                     LRMANDRRIWWRFHLYSIPMLLWAALVGYVLLVILPAN"
     gene            complement(3965..4432)
                     /gene="mntR"
                     /locus_tag="RHX21_004288"
     CDS             complement(3965..4432)
                     /gene="mntR"
                     /locus_tag="RHX21_004288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-binding transcriptional regulator
                     MntR"
                     /protein_id="HDV1989385.1"
                     /translation="MSRRAGTPTAKKVTQLVNVEEHVEGFRQVREAHRRELIDDYVEL
                     ISDLIREVGEARQVDMAARLGVSQPTVAKMLKRLATMGLIEMIPWRGVFLTAEGEKLA
                     QESRERHQIVENFLLVLGVSPEIARRDAEGMEHHVSEETLDAFRLFTQKHGAK"
     gene            4618..4746
                     /gene="mntS"
                     /locus_tag="RHX21_004289"
     CDS             4618..4746
                     /gene="mntS"
                     /locus_tag="RHX21_004289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganase accumulation protein MntS"
                     /protein_id="HDV1989386.1"
                     /translation="MNEFKRCMRVFSHSPFKVRLMLLSMLCDMVNNKPQQDKPSDK"
     gene            5018..6601
                     /gene="opgE"
                     /locus_tag="RHX21_004290"
     CDS             5018..6601
                     /gene="opgE"
                     /locus_tag="RHX21_004290"
                     /EC_number="2.7.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HDV1989387.1"
                     /translation="MNLTLKESLVTRSRVFSPWTAFYFLQSLLINLGLGYPFSLLYTA
                     AFTAILLLLWRTLPRVQKVLVGISSLVAACYFPFAQAYGAPNFNTLLALHSTNMEEST
                     EILTIFPWYSYMVGIFIFVLGVIAIRRKKESEKARWNTFDSLCLVFSVATFFVAPVQN
                     LAWGGVFKLKDTGYPVFRFAKDVIVNNNEVIEEQERMAKLSGMKDTWTVTAVKPKYQT
                     YVVVIGESARRDALGAFGGHWDNTPFASSVNGLIFADYIAASGSTQKSLGLTLNRVVD
                     GKPQFQDNFVTLANRAGFQTWWFSNQGQIGEYDTAIASIAKRADEVYFLKEGNFEADK
                     NTKDEALLDMTAQVLAQEHSQPQLIVLHLMGSHPQACDRTQGKYETFVQSKETSCYLY
                     TMTQTDDLLRKLYDQLRNSGSSFSLVYFSDHGLAFKERGKDVQYLAHDDKYQQNFQVP
                     FMVISSDDKAHRVIKARRSANDFLGFFSQWTGIKAKEINIKYPFISEKKAGSIYITNF
                     QLQKVDYNHLGTDIFDPKP"
     gene            complement(6650..7165)
                     /gene="ompX"
                     /locus_tag="RHX21_004291"
     CDS             complement(6650..7165)
                     /gene="ompX"
                     /locus_tag="RHX21_004291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpX"
                     /protein_id="HDV1989388.1"
                     /translation="MKKIACLSALAAVLAFTAGTSVAATSTVTGGYAQSDAQGQMNKM
                     GGFNLKYRYEEDNSPLGVIGSFTYTEKSRTASSGDYNKNQYYGITAGPAYRINDWASI
                     YGVVGVGYGKFQTTEYPTYKHDTSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDV
                     GTWIAGVGYRF"
     gene            complement(7218..7283)
                     /locus_tag="RHX21_004292"
     CDS             complement(7218..7283)
                     /locus_tag="RHX21_004292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989389.1"
                     /translation="METFCYMKWPVRHHKSRRVSH"
     gene            7518..8405
                     /gene="rhtA"
                     /locus_tag="RHX21_004293"
     CDS             7518..8405
                     /gene="rhtA"
                     /locus_tag="RHX21_004293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/homoserine exporter RhtA"
                     /protein_id="HDV1989390.1"
                     /translation="MPGSLRKMPVWLPIIILLVAMASIQGGASLAKSLFPLVGAPGVT
                     ALRLALGTLILIAFFKPWRLRFAKEQRLPLLFYGVSLGGMNYLFYLSIQTVPLGIAVA
                     LEFTGPLAVALFSSRRPVDFVWVVLAVLGLWFLLPLGQDVSHVDLTGSALALGAGACW
                     AIYILSGQRAGAEHGPATVAIGSLIAALIFVPIGALQAGEALWHWSVIPLGLAVAILS
                     TALPYSLEMIALTRLPTRTFGTLMSMEPALAAVSGMIFLGETLTPIQLLALGAIIAAS
                     MGSTLTVRKESKIKELDIN"
BASE COUNT         2076 a         2229 c         2014 g         2089 t
ORIGIN      
        1 attttgcatt tgtcatcagc cgccgtcacc ccgacagtat cggggtgacg gataatcact
       61 tactcgatcc ctttactacg caggtaatct tcgtaattac cgctaaagtc gatcacgcgt
      121 tccggggtga tttccagaat gcgggtcgcc agggagctta cgaactcacg gtcgtgtgaa
      181 acaaagatca gcgtgccctg atacagttcc agcgccatgt tcagtgactc gatggattcc
      241 atatccaggt ggttggtcgg ttcgtccatg atcagaatgt tcggcttctg catcattaac
      301 ttaccaaaaa gcatccgccc tttttctcca ccggaaagca ctttagctgg ctttttgatg
      361 tcgtcctggc tgaacagcaa acgaccgaga atgctgcgta ccgcctgctc gtcatcgcct
      421 tcctgcttcc actggctcat ccattcgaac acggtcagat cattttcaaa ctcatattcg
      481 tggtcctggg cgtagtaacc aatgcgcgcg ttttcagacc attttacggt gccgctgtcc
      541 ggttgcagat cgcccaccag cgttttcagc agcgttgatt taccgacgcc gttggtaccc
      601 agtaccgcaa gtttttcacc gacctccagc agcaggttga gatttttaaa cagtggaccg
      661 ttatcaaacc ctttggtcag accttccact tccagcgcgt tacggaacag tttcttatcc
      721 tgttcaaaac ggatgaacgg gttctgacgg ctggaggctt tcacctcttc cagtttgatt
      781 ttatcaatct ggcgcgcgcg cgaagttgcc tggcgagatt tcgaggcgtt ggcgctaaag
      841 cggctaacga aagattgcaa ctcagcaatc tgcgctttct tcttggcgtt atcggccagc
      901 agacgttcac gcgcctgggt cgccgccgtc atgtactcat cgtagttacc cggataaacg
      961 cgcagctcgc cgtaatccag atccgccatg tgggtacaga ccatgttaag gaagtgacgg
     1021 tcgtgcgaga tgatgatcat ggtgctgtca cgctcgttca gcacctgttc cagccagcga
     1081 atggtgtcga tgtcgaggtt gttggtcggt tcgtcgagca ggagaatatc cggatcagca
     1141 aacagcgcct gcgccagaag cacacgcagc ttccagccag gagcaacttc actcatcggg
     1201 ccgtagtgct gttccactgg aattcccacg ccaagcaaca attcaccggc gcgagcttcc
     1261 gcagagtaac cgtccatttc gccgtattta acttccagat cggccacttt atagccgtct
     1321 tcctcactca tttccggcaa agcatagatg cggtcacgct cctgcttcac ttcccacaac
     1381 tctttatgcc ccatgatcac cgtatccagc acagtgaact cttcaaaggc aaactgatcc
     1441 tgacgcagct taccaatgcg ctcgttggga tcgagggaaa cgttacccaa agtcggctct
     1501 aagtcgccgc cgaggatctt cataaaggtg gatttaccac taccgttcgc gccaatcagg
     1561 ccgtaacggt tgccgccgcc aaatttgacg gaaatgtttt caaacaacgg cttactgccg
     1621 aactgcatgg tgacgttact ggaaactaac acaggcgtat cctgaaaaga gatatgacaa
     1681 accgcgcatt atgccataag tctgaaagaa gatcctgctc ctcgcttaag gtctacactc
     1741 aagccaaagg caaaaaatgt gatttcgtac acatctgatt tcactgtgag ctggaatgaa
     1801 cttataatgc gcttccaata ctctaatatt ctcaacccaa tggcctgcca ggcacaaaat
     1861 ctcgcttaac atgaatatga aattgaaaac attattcgca gcggccttcg ctgttgtcgg
     1921 cttttgcagt accgcctctg cggtaactta tcctctgcca accgacggga gtcgcctggt
     1981 tggtcagaat caggtgatca ccattcctga aggtaacact cagccgctgg agtattttgc
     2041 cgcggagtac cagatggggc tttccaatat gatggaagcg aacccgggtg tggatacctt
     2101 cctgccgaaa ggcggtactg tactgaacat tccgcagcag ctgatcctgc cggataccgt
     2161 tcatgaaggc atcgtcatta acagtgcaga gatgcgtctg tattactatc cgaaagggac
     2221 caacaccgtt atcgtgctgc cgatcggcat tggtcagtta ggcaaagata cgcctatcaa
     2281 ctggaccacc aaagttgagc gtaagaaagc aggcccgacc tggacgccga ccgccaaaat
     2341 gcacgcagag taccgcgctg cgggcgaacc gcttccggct gtcgttccgg caggtccgga
     2401 taacccgatg ggtctgtatg cactctacat cggtcgcctg tatgctatcc atggcaccaa
     2461 cgccaacttc ggtatcggcc tgcgtgtaag tcatggttgt gtgcgtctgc gtaacgaaga
     2521 catcaaattc ctgttcgaga aagtaccggt cggtacccgc gtacagttta ttgatgagcc
     2581 ggtaaaagcg accaccgagc cagacggcag ccgttatatt gaagtccata acccgctgtc
     2641 taccaccgaa gcccagtttg aaggtcagga aattgtgcca attaccctga cgaagagcgt
     2701 gcaaacagtg accggtcagc cagatgttga ccaggttgtt cttgatgaag cgattaaaaa
     2761 ccgctccggg atgccggttc gtctgaatta atcttcaaaa cttaaagcaa aaggcggact
     2821 cataatccgc cttttttatt tgccagaccc tagttggccg ggagtataac taacaaaaca
     2881 tatcccacca acgccgccca caacagcatc ggtattgaat agagatggaa acgccaccag
     2941 atgcggcgat cgttcgccat acgtagcgca atcaaatttg ccagcgatcc gggtaataac
     3001 ccaaagccac ctacgtttac cgcccatacc agtaataaag acggcggcac atagttcagc
     3061 aacaatatgg tactcggcac gttactgatc acctgcgata aaccgattgc cgttaaccat
     3121 aacccgggtt cagatagatg actcacgtta cccaacacgc cttgcaacgc tggaagctgg
     3181 gtcagtaaat ggacgtcgat aaacatcgcc ataaacacca gcagcagcgt ccagtccaca
     3241 ctgagcacca cgcgacgtgc cagcagcgca aagcctgccg ccacaatcac cagtccccac
     3301 agctcttgtt tgaactccag cgccgtcaga aagacgatat acagccccag acaactccac
     3361 accagccgcg gtttccactc cggtgtttgc acccccgtat ggtattgcag cgcctttcca
     3421 gggaaacaac accagcacag gagcaggagc gtcagcatca ttgcgccagc cagcggtgcc
     3481 atttgggcaa taaatccggc aaacgaaaga ccagaacgtc cccagataag aatattttgc
     3541 gggttgccaa ttgccgtcag tagcgaacca gcgttgactg ccagcgcctc aaaaataatc
     3601 agccgattaa ccgggatctc acacagtctt tttagcgtga tagtcagcgg aacaacaata
     3661 aacagcgcga catcgttggt cagaaaggta gaaagcagcg ccgccgccag caccataaac
     3721 atcgccagcc gacgctccgt agcaaagcgg cgcaccattt tgcgccccag cacatcaaaa
     3781 taaccgctta actccacacc tttggtcagc agcatcaggc cgcttaaggt gatgatggtg
     3841 tgccagtcga tagcagcagg ccaggatttc ggtgcaaagg gcacgaaaaa gcttaatccg
     3901 ataccaacaa gaattaataa ctgaaaaaaa cgatcgcctt gcagcgtgcg taaaaaaggc
     3961 aggctcattt ggcaccgtgt ttctgggtaa acaaacgaaa agcgtcgagc gtctcttcac
     4021 taacatggtg ctccatgcct tccgcgtcgc gacgggcgat ttccggactg acgcccaaca
     4081 ccaacaagaa attttcgact atctgatgtc gctcgcggct ttcctgcgcc agcttctctc
     4141 cttctgccgt taaaaacacg ccacgccagg ggatcatttc aatcagcccc atggttgcca
     4201 gccgcttaag cattttagcc accgtcggtt gcgaaactcc cagacgagca gccatgtcca
     4261 cctgacgagc ttcccccact tccctgatca agtcagaaat cagctcaacg taatcatcaa
     4321 taagctcgcg ccgatgcgcc tctctgacct ggcggaaccc ttcaacgtgc tcttccacgt
     4381 tcactaactg cgtcactttt tttgctgttg gcgtacctgc gcgacgactc attgtgcttc
     4441 ctcattatgg tgacgcatac atagcgttct catttcgtgc gcacattgta aaccagagtt
     4501 gcgaaggtac aaaaaattaa cgttttagca atagctatat aatatagcct gtgctatatc
     4561 tgtatgtaat gcaatcatcc ctcaaggatc gacgggatta gcaagtcagg aggtcttatg
     4621 aatgagttca agaggtgtat gcgcgtgttt agtcattctc cctttaaagt acggttaatg
     4681 ctgctctcta tgttgtgcga tatggtcaac aacaaaccgc agcaagataa accttccgat
     4741 aaatagcggc gtcgcggtac gccgcttcac tcctgctttc atgcaggcat aacgcgtttt
     4801 ggtctgaaaa accccacttt ttgtcggatt tgcaatcccc ttcgcaaaag atttgtacgt
     4861 cagtagttga cctgaacggc ggctcgctct atcttcttgc agccctgcgt atattgcggc
     4921 tcgcggatgc ggaccccttt ccactcttca cgcactcttg caggtattga cccttgacgc
     4981 cagggtaagc acatggcgtt tgttacgata gtggcatatg aatttaaccc tcaaagaatc
     5041 gcttgttacc cgtagccggg tatttagccc gtggactgcg ttctactttt tacagtcgct
     5101 attaattaac ctcggcttag gttacccctt cagtttgctc tacaccgctg cgtttacggc
     5161 tattttgctt ttgctatggc gaacattgcc tcgcgtacaa aaagttctgg tcggtatcag
     5221 ttcgctggtg gcggcttgtt atttcccttt tgctcaggcc tacggcgcgc ctaacttcaa
     5281 tacattgctg gcattgcact ccaccaatat ggaagagtcg accgaaatcc tgacgatttt
     5341 tccgtggtac agctacatgg tcggcatatt tatttttgtg ctcggcgtaa tagcaatcag
     5401 gcgaaaaaaa gagagtgaaa aagcgcgctg gaataccttc gacagcctgt gtctggtatt
     5461 cagtgtggcg acattttttg ttgctcccgt gcaaaacctg gcctggggcg gcgtatttaa
     5521 actgaaagat actggctatc cggtatttcg ttttgctaag gatgtcatcg tcaataataa
     5581 cgaggtgatt gaagagcaag aacggatggc aaaactttcc ggaatgaaag atacctggac
     5641 ggtcactgcc gttaagccga agtatcagac ctatgtggtg gtgatcggtg aaagcgcgcg
     5701 tcgcgatgcc ctcggtgcct ttggcggtca ctgggacaat accccgtttg ccagcagcgt
     5761 taacggtttg atatttgctg actacattgc cgccagtggc tccacgcaga aatcgcttgg
     5821 cttaacgctc aatcgcgtag tcgatggcaa accacagttt caggataact ttgtcaccct
     5881 ggcaaatcgc gcgggcttcc agacctggtg gttttccaac cagggccaaa tcggcgaata
     5941 cgatactgct atcgccagca tcgccaaacg agcagatgaa gtgtacttcc tgaaagaagg
     6001 taattttgaa gcagataaaa ataccaaaga cgaagcgtta ctggatatga ccgctcaagt
     6061 gctggcgcaa gagcactcgc aaccgcagct gattgttcta catctgatgg gctcacatcc
     6121 gcaggcctgc gacaggacac aaggcaaata cgaaaccttt gtgcagtcga aagaaacgtc
     6181 gtgctatctc tataccatga cgcaaacgga cgatttactg cgcaagctgt acgatcagtt
     6241 acgcaacagc ggcagcagct tctcgctggt ttacttttct gaccacggtc tggcctttaa
     6301 agagcgcggc aaagacgtgc aataccttgc ccatgatgat aagtatcagc aaaatttcca
     6361 ggtgcctttt atggtcattt ccagcgacga taaagcgcat cgggtgatta aagcccgccg
     6421 ctcagccaat gacttcttag gttttttctc ccagtggacg ggaattaaag cgaaggaaat
     6481 taacatcaaa tacccgttta tatctgagaa gaaagccggg tcgatataca tcaccaactt
     6541 ccagttacag aaggtggatt acaaccatct cggaaccgat attttcgacc cgaagcctta
     6601 aaaacaaaaa tccgccccga gaggcggatt ttttatatca ccaaagtgat tagaagcggt
     6661 aaccaacacc ggcaatccag gtgcctacgt caacgctacg aatacggctc tgctcgtaag
     6721 agaagtccag agcaacgttt tccatcgggt tgaactgcag accagcaccg taggagaaac
     6781 cgtagtcgct ggtgtcgtgt ttgtaggtcg ggtattcagt ggtctggaat ttaccataac
     6841 ccacacccac tacaccgtag atgcttgccc agtcgttaat gcggtaagcc ggaccagcag
     6901 tgatgccgta gtactggttt ttgttgtagt caccagagct tgcagtacgg cttttctcgg
     6961 tgtaagtgaa agaaccgatc acacccagcg ggctgttgtc ttcttcatag cggtatttca
     7021 ggttgaaacc gcccattttg ttcatttggc cctgagcgtc gctctgtgcg taaccgccag
     7081 ttacggtaga agtcgcagct acggaagtac ctgcggtgaa agccagaact gcggccagtg
     7141 ctgaaagaca tgcaattttt ttcataacca cctcaaatgt gattcaaata agtcctaagt
     7201 tttaaatata tcaaaaatta atgggaaact cttcgcgatt tgtgatgtct aacgggccat
     7261 ttcatgtaac agaacgtttc catacaccgc tatccatcta aatttaaatc actttttcag
     7321 agaactgcgt aagtattacg catgttttcc ctgtcattca tccagattat tcctaatcac
     7381 cagactaatg attccatcaa tcctggcgca ttttagtcaa aacgggggaa aattttttca
     7441 acaaatgctc aaccagcatt gggtatatcc agtacactcc acgctttact taagtctaga
     7501 tatttgtggg agaaaggatg cctggttcat tacgtaaaat gccggtctgg ttaccaataa
     7561 tcatattgct cgttgccatg gcgtctattc agggtggagc ctcgttagct aagtcacttt
     7621 ttcctctggt gggcgcaccg ggtgtcactg cgctgcgtct ggcattagga acgctgatcc
     7681 tcatcgcgtt ctttaagcca tggcgactgc gctttgccaa agagcaacgg ttaccgctgt
     7741 tgttttacgg cgtttcgctg ggtgggatga attatctttt ttatctttct attcagacag
     7801 taccgctggg tattgcggtg gcgctggagt tcaccggacc actggcggtg gcgctgttct
     7861 cttctcgtcg cccggtagat ttcgtctggg ttgtgctggc ggttcttggt ctgtggttcc
     7921 tgctaccgct ggggcaagac gtttcccatg tcgatttaac cggcagtgcg ctggcactgg
     7981 gggccggggc ttgttgggct atttacattt taagtgggca acgcgcagga gcggaacatg
     8041 gccctgcgac ggtggcaatt ggttcgttga ttgcagcgtt aattttcgtg ccaattggag
     8101 cgcttcaggc tggtgaagca ctctggcact ggtcggttat tccattgggt ctggctgtcg
     8161 ctattctctc gaccgctctg ccttattcgc tggaaatgat tgccctcacc cgtttgccaa
     8221 cacggacatt tggtacgctg atgagcatgg aaccggcgct ggctgccgtt tccgggatga
     8281 ttttcctcgg agaaacactg acacccatac agctgctggc gctcggcgct atcatcgccg
     8341 cttcaatggg gtctacgctg acagtacgca aagagagcaa aataaaagaa ttagacatta
     8401 attaaatt
//
LOCUS       DAPGUL010000166         8382 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.169, whole genome shotgun sequence.
ACCESSION   DAPGUL010000166 DAPGUL010000000
VERSION     DAPGUL010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8382
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.169"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            276..1253
                     /gene="csiD"
                     /locus_tag="RHX21_004294"
     CDS             276..1253
                     /gene="csiD"
                     /locus_tag="RHX21_004294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311547.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation induced protein CsiD"
                     /protein_id="HDV1989391.1"
                     /translation="MNALTAVQNNAVDSGQDYSGFTLIPSAQSPRLLELTFTEQTTKQ
                     FLEQVAEWPVQALEYKSFLRFRVGKILDDLCANQLQPLLLKTLLNRAEGALLINAVGI
                     DDVAQADEMVKLATAVAHLIGRSNFDAMSGQYYARFVVKNVDNSDSYLRQPHRVMELH
                     NDGTYVEEITDYVLMMKIDEQNMQGGNSLLLHLDDWEHLDHYFRHPLARRPMRFAAPP
                     SKNVSKDVFHPVFDVDQQGRPVMRYIDQFVQPKDFEEGVWLSELSDAIETSKGILSVP
                     VPVGKFLLINNLFWLHGRDRFTPHPDLRRELMRQRGYFAYATHHYQTHQ"
     gene            1273..2541
                     /gene="lhgO"
                     /locus_tag="RHX21_004295"
     CDS             1273..2541
                     /gene="lhgO"
                     /locus_tag="RHX21_004295"
                     /EC_number="1.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311548.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-hydroxyglutarate oxidase"
                     /protein_id="HDV1989392.1"
                     /translation="MYDFVIIGGGIIGMSTAMQLIDVYPDARIALLEKESGPACHQTG
                     HNSGVIHAGVYYTPGSLKAQFCLAGNRATKAFCDQNGIRYDNCGKMLVATSELEMERL
                     RALWERTAANGIEREWLNAMELREREPNITGLGGIFVPSSGIVSYRNVTAAMAKIFQA
                     RGGEIIYNAEVSGLSEHKNGVVIRTRQGGEYEASTLISCSGLMADRLVKMLGLEPGFI
                     ICPFRGEYFRLAPEHNQIVNHLIYPIPDPAMPFLGVHLTRMIDGSVTVGPNAVLAFKR
                     EGYRKRDFSFSDTLEILGSSGIRRVLQNHLRSGLGEMKNSLCKSGYLRLVQKYCPRLS
                     LSDLQPWPAGVRAQAVSPDGKLIDDFLFVTTPRTIHTCNAPSPAATSAIPIGAHIVSK
                     VQTLLASQSNPGRTLRAARSVDALHAAFNQ"
     gene            2564..4012
                     /gene="gabD"
                     /locus_tag="RHX21_004296"
     CDS             2564..4012
                     /gene="gabD"
                     /locus_tag="RHX21_004296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HDV1989393.1"
                     /translation="MKLNDSNLFRQQALINGEWLDANNGEVIDVTNPANGDKLGSVPK
                     MGADETRAAIDAANRALPAWRALTAKERANILRNWFNLMMEHQDDLARLMTLEQGKPL
                     AEAKGEISYAASFIEWFAEEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPA
                     AMITRKAGPALAAGCTMVLKPASQTPFSALALAELAIRAGIPAGVFNVVTGSAGAVGN
                     ELTSNPLVRKLSFTGSTEIGRQLMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEG
                     ALASKFRNAGQTCVCANRLYVQDGVYDRFAEKLQQAVSKLHIGDGLDKGVTIGPLIDE
                     KAVAKVEEHIADALEKGARVVCGGKAHERGGNFFQPTILVDVPANAKVSKEETFGPLA
                     PLFRFKDEADVIAQANDTEFGLAAYFYARDLSRVFRVGEALEYGIVGINTGIISNEVA
                     PFGGIKASGLGREGSKYGIEDYLEIKYMCIGL"
     gene            4026..5306
                     /gene="gabT"
                     /locus_tag="RHX21_004297"
     CDS             4026..5306
                     /gene="gabT"
                     /locus_tag="RHX21_004297"
                     /EC_number="2.6.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-aminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="HDV1989394.1"
                     /translation="MSSNKELMQRRSQAVPRGVGQIHPIFADRAENCRVWDVEGREYL
                     DFAGGIAVLNTGHLHPKVVAAVEAQLKKLSHTCFQVLAYEPYLELCEIMNQKVPGDFA
                     KKTLLVTTGSEAVENAVKIARAATKRSGTIAFSGAYHGRTHYTLALTGKVNPYSAGMG
                     LMPGHVYRALYPCPLHGISEDDAIASIHRIFKNDAAPEDIAAIVIEPVQGEGGFYAAT
                     PAFMQRLRALCDEHGIMLIADEVQSGAGRTGTLFAMEQMGVAPDLTTFAKSIAGGFPL
                     AGVTGRAEVMDAVAPGGLGGTYAGNPIACVAALEVLKVFEQENLLQKANDLGQKLKDG
                     LLAIAEKHPEIGDVRGLGAMIAIELFEDGDHSKPDAKLTAGIVARARDKGLILLSCGP
                     YYNVLRILVPLTIEDAQIRQGLEIINQCFAEAKQ"
     gene            5543..6943
                     /gene="gabP"
                     /locus_tag="RHX21_004298"
     CDS             5543..6943
                     /gene="gabP"
                     /locus_tag="RHX21_004298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GABA permease"
                     /protein_id="HDV1989395.1"
                     /translation="MGQSSQPHELGGGLKSRHVTMLSIAGVIGASLFVGSSVAIAEAG
                     PAVLLAYLFAGLLVVMIMRMLAEMAVATPDTGSFSTYADKAIGRWAGYTIGWLYWWFW
                     VLVIPLEANIAAMILHSWVPGIPIWLFSLVITLALTGSNLLSVKNYGEFEFWLALCKV
                     IAILAFIFLGAVAISGFYPYAEVSGISRLWDSGGFMPNGFGAVLSAMLITMFSFMGAE
                     IVTIAAAESDTPEKHIVRATNSVIWRISIFYLCSIFVVVALIPWNMPGLKAVGSYRSV
                     LELLNIPHAKLIMDCVILLSVTSCLNSALYTASRMLYSLSRRGDAPAVMGKINRSKTP
                     YVAVLLSTGAAFLTVVVNYYAPAKVFKFLIDSSGAIALLVYLVIAVSQLRMRKILRAE
                     GSEIRLRMWLYPWLTWLVIGFITFVLVVMLFRPAQQLEVISTGLLAIGIICTVPIMAR
                     WKKLVLWQKTPVHNTR"
     gene            6964..7626
                     /gene="csiR"
                     /locus_tag="RHX21_004299"
     CDS             6964..7626
                     /gene="csiR"
                     /locus_tag="RHX21_004299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311552.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CsiR"
                     /protein_id="HDV1989396.1"
                     /translation="MTITSLDGYRWLKNDIIRGNFQPDEKLRMSLLTSRYALGVGPLR
                     EALSQLVAERLVTVVNQKGYRVASMSEQELLDIFDARANMEAMLVSLAIARGGDEWEA
                     DVLAKAHLLSKLEACDASEKMLDEWDLRHQAFHTAIVAGCGSHYLLQMRERLFDLAAR
                     YRFIWLRRTVLSVEMLEDKHDQHQTLTAAVLARDTARASELMRQHLLTPIPIIQQAMA
                     GN"
     gene            complement(7627..8076)
                     /gene="kbp"
                     /locus_tag="RHX21_004300"
     CDS             complement(7627..8076)
                     /gene="kbp"
                     /locus_tag="RHX21_004300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium binding protein Kbp"
                     /protein_id="HDV1989397.1"
                     /translation="MGLFNFVKDAGEKLWDAVTGQHDKDDQAKKVQEHLSKTGIPDAD
                     KVNIQIADGKATVTGDGLSQEAKEKILVAVGNISGIASVDDQVKTATPATASQFYTVK
                     SGDTLSAISKQVYGNANLYNKIFEANKPMLKSPDKIYPGQVLRIPEE"
     gene            complement(8160..8318)
                     /locus_tag="RHX21_004301"
     CDS             complement(8160..8318)
                     /locus_tag="RHX21_004301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaE/Pmp3 family membrane protein"
                     /protein_id="HDV1989398.1"
                     /translation="MGFWRIVITIILPPLGVLLGKGFGWAFIINILLTLLGYIPGLIH
                     AFWVQTRD"
BASE COUNT         1887 a         2198 c         2346 g         1951 t
ORIGIN      
        1 cattttgcag tgaagccatt tactgttttt tatcgaccag ataatctgtt ctctaatgtt
       61 aactccccct aacctgttgc tttagttatt catttcctgt ctcactttgc cttaataccc
      121 tacgttaaat gttactaatt tgttgctttt gatcacaata agaaaacaat atgtcgcttt
      181 tgtgcgcatt tttcagaaat gtagatattt ttagattatg gctacgaaat gagcatcgcc
      241 atgtcaccct acatctcata agaggatcgc ttctgatgaa tgcactgacc gccgtacaaa
      301 ataacgctgt cgattcaggc caggactata gcggattcac tctcatcccg tcggcgcaat
      361 ccccgcgtct gctggaactc accttcaccg aacagacgac caaacagttt ctcgaacagg
      421 ttgccgaatg gcccgtgcag gcgctggagt acaaatcgtt tctgcgtttt cgggtaggca
      481 aaattcttga cgatctgtgt gcgaatcagc tgcaaccatt gctgttgaag accctgctaa
      541 accgcgctga aggtgcgctg ttgatcaatg cggtgggtat cgatgatgtg gcgcaggcag
      601 atgagatggt gaagctggca acggcggtag cgcatctgat tggtcgctca aatttcgatg
      661 cgatgagcgg tcagtattac gcgcgtttcg tggtgaaaaa tgtcgataac tcagacagct
      721 atctgcgtca gccgcaccgc gtgatggaac tgcacaacga cggcacgtat gtcgaagaga
      781 tcaccgatta cgtgctgatg atgaaaatcg atgagcaaaa catgcagggt ggaaattcgt
      841 tgctgctgca tctcgatgac tgggaacatc tggaccacta tttccgccat ccactggcgc
      901 gtcgcccgat gcgctttgcc gcgccgccga gcaaaaacgt cagcaaagat gttttccatc
      961 cagtgttcga cgttgatcaa cagggtcgcc cggtgatgcg ctatatcgac cagttcgtcc
     1021 agccaaaaga ttttgaagaa ggcgtgtggt tgagcgagct ttccgatgcc attgaaacca
     1081 gcaaaggcat tctttctgta cccgttcccg ttggcaaatt cctgttgata aacaacctgt
     1141 tctggctgca cggtcgcgac cgctttactc cgcacccgga tctgcgccgt gaactgatgc
     1201 gtcagcgtgg ctatttcgct tacgccactc accactacca gacgcatcag taagcgcaaa
     1261 ggaattgagc ggatgtatga ttttgtgatt attggcggcg gcatcatcgg catgtcgacc
     1321 gccatgcaac tgattgatgt ttatccggat gcccgcattg cgttgctgga aaaagagtcc
     1381 ggcccggcct gtcaccagac gggccacaac agcggcgtga tccatgccgg ggtttattac
     1441 acgcccggta gcctgaaggc gcagttttgc ctggcgggaa accgcgccac caaagccttt
     1501 tgcgatcaaa acggcattcg ctatgacaac tgcggcaaga tgctggtcgc cacctctgaa
     1561 ctcgaaatgg aacggttgcg cgcgttgtgg gaacgcacgg cggcaaacgg tatcgagcgc
     1621 gagtggttaa acgccatgga actgcgcgag cgcgaaccga atatcaccgg gcttggcggc
     1681 atttttgtgc catccagcgg cattgtcagc taccgcaacg tgacggcggc aatggcaaaa
     1741 atcttccagg ccagaggcgg tgagattatc tataacgccg aagtcagcgg cctcagtgag
     1801 cataaaaacg gcgtggtgat acgtacccgc cagggcggcg aatatgaagc atcgacgctg
     1861 attagctgtt ccgggctgat ggctgaccgg ctggtgaaaa tgctcggcct cgaaccgggc
     1921 tttattatct gcccgttccg cggcgagtat ttccgccttg cgccggagca taaccagatt
     1981 gttaaccatc tgatttaccc tattcccgac ccggcaatgc cgtttttggg cgtgcatctc
     2041 acccgaatga tcgatggcag cgtgaccgtc gggccaaacg cggtgctggc ttttaaacgc
     2101 gaaggctacc gcaagcgcga cttctcgttt agcgacacgc tggaaatttt aggctcgtcg
     2161 gggattcgcc gggtgctgca aaaccatcta cgctcaggac tgggcgagat gaaaaactcg
     2221 ctgtgcaaaa gcggctatct gcggctggtg caaaagtatt gtccccggct ttcgttaagc
     2281 gatctccagc cctggcccgc cggtgtgcgg gcgcaggcgg tatcgccgga tggcaagttg
     2341 attgacgatt ttctgtttgt caccaccccg cgcacgatcc acacctgcaa tgcgccctcc
     2401 ccggcagcga catcagcaat tcctattggt gcgcatattg tcagcaaggt acaaacgctg
     2461 ttggcaagcc agagtaaccc cggacgcacg ctgcgagcgg cacgtagtgt ggatgcctta
     2521 cacgccgcat ttaatcaata acctttgaaa acaggacgta acaatgaaac ttaacgacag
     2581 taacttattc cgccagcagg cgttgattaa cggggaatgg ctggacgcca acaatggcga
     2641 ggtcatcgac gtcaccaatc cggcgaacgg cgacaagctg ggtagcgtac ccaaaatggg
     2701 cgctgatgaa acccgcgccg ctatcgacgc cgccaaccgc gctctgcccg cctggcgtgc
     2761 gctcaccgcc aaagaacgcg ccaacattct gcgcaactgg ttcaatttga tgatggagca
     2821 tcaggacgat ttagcgcgtc tgatgaccct cgaacagggt aaaccgctgg ctgaagcgaa
     2881 aggtgaaatc agctacgccg cctcctttat tgagtggttt gctgaagaag gcaaacgcat
     2941 ttatggcgac accattcccg gtcatcaggc cgataaacgc ctgattgtta tcaagcagcc
     3001 gattggcgtt accgccgcca tcacgccgtg gaacttcccg gcggcgatga ttacccgtaa
     3061 agccggtccg gcgctggcgg caggctgcac gatggtgctg aaacccgcca gtcagacgcc
     3121 gttctctgcg ctggcgctgg cggagctggc gattcgcgcg ggcattccgg ctggggtatt
     3181 taacgtggtc accggttcgg cgggcgcagt cggtaacgaa ctgaccagca acccgctggt
     3241 gcgcaaactg tcgtttaccg gttcgaccga aattggccgc cagttaatgg aacaatgcgc
     3301 gaaagacatc aaaaaagtgt cgctggagct cggcggcaac gcgccgttta tcgtctttga
     3361 cgatgccgac ctcgacaaag ccgtggaagg cgcgctggcc tcgaaattcc gcaacgccgg
     3421 gcaaacctgc gtctgcgcca accgtttata cgtgcaggac ggcgtgtatg accgctttgc
     3481 cgaaaaattg cagcaggcgg tgagcaaact gcacatcggc gacgggctgg ataaaggcgt
     3541 caccatcggg ccgctgatcg atgaaaaagc agtagcaaaa gtggaagagc atattgccga
     3601 tgcgctggag aaaggcgcgc gcgtggtttg cggcggtaaa gcacacgaac gtggcggcaa
     3661 cttcttccag ccgaccattc tggtggacgt tccggccaac gctaaagtgt cgaaagaaga
     3721 gacgttcggc cccctcgccc cgctgttccg ttttaaagat gaagccgatg tgatcgcgca
     3781 agccaatgac accgaatttg gtcttgccgc ctatttctac gcccgtgatt taagccgcgt
     3841 cttccgcgtg ggcgaagcgc tggagtacgg catcgtcggc atcaataccg ggattatttc
     3901 caatgaagtg gccccgttcg gcggcatcaa agcctcgggt ctgggtcgtg aaggttcgaa
     3961 gtatggcatc gaagattact tagaaatcaa atatatgtgc atcggtcttt aactggagaa
     4021 cgcgaatgag cagcaataaa gagttaatgc agcgccgcag tcaggcagtt cctcgtggcg
     4081 ttgggcaaat tcacccgatt ttcgctgacc gcgcggaaaa ctgccgggtg tgggacgttg
     4141 aaggccgtga gtatcttgat ttcgcgggcg ggattgcggt gctcaatacc gggcacctgc
     4201 atccgaaggt ggttgcggcg gtggaagcgc agttgaaaaa actgtcgcac acctgcttcc
     4261 aggtgctggc ctacgagccg tatctggagc tgtgcgagat tatgaatcag aaggtgccag
     4321 gcgatttcgc caagaaaacg ctgctggtta cgaccggttc cgaagcggtg gaaaacgcgg
     4381 tgaaaatcgc ccgcgccgcc acaaaacgta gcggcaccat cgcttttagc ggcgcgtacc
     4441 acgggcgcac gcattacacg ctggcgctga ccggcaaggt gaatccgtac tctgcgggca
     4501 tggggctgat gcctgggcac gtttatcgcg cgctttatcc ttgcccgctg cacggcatca
     4561 gtgaagatga cgctatcgcc agcattcacc gaatttttaa aaatgacgct gcgccggaag
     4621 atatcgccgc catcgtgatt gaaccggttc agggcgaagg cggtttctac gccgctacgc
     4681 ctgcttttat gcagcgttta cgcgcgctgt gtgacgagca cgggatcatg ctgattgccg
     4741 atgaagtgca gagcggcgcg gggcgtaccg gcacgctgtt tgcgatggag cagatgggcg
     4801 ttgcgccgga tctcaccacc tttgcgaaat ccatcgcggg cggcttcccg ctggcgggtg
     4861 tcaccgggcg cgcggaagtg atggatgccg tcgctccagg cgggctgggc ggcacctatg
     4921 ccggtaaccc gattgcctgc gtggcggcgc tggaagtgtt gaaggtgttc gagcaggaaa
     4981 atctgctgca aaaagccaac gatctggggc agaagctgaa agatggactg ctggcgattg
     5041 ccgaaaaaca cccggagatc ggcgacgtac gcgggctggg agcgatgatc gccatcgagc
     5101 tgtttgaaga tggcgatcac agcaaaccgg acgcaaaact caccgccggg atcgtggcgc
     5161 gcgcccgcga taaaggcctg attcttctct cctgcggccc gtattacaac gtgctgcgca
     5221 tccttgtacc gctcaccatt gaagacgctc agatccgtca gggtctggag atcatcaacc
     5281 agtgttttgc tgaggcgaag cagtagcacc gcaccatgcc ggaggcgacg ctgcgcgtct
     5341 tgtccggcct acggtgatcc aggtcggata aggcgtttac gccgcatccg acaatctgta
     5401 cgtgaacagg aataaatcta tgtcggccgg ataaggcgga gccgctctcc ggcaaaaaga
     5461 atcaataaca attaaacgcg tgacccgacg cgggaaatgt cggggcgctc tcccaagtga
     5521 cacactttcg agaggattca ggatggggca atcatcgcaa ccacatgagt taggcggcgg
     5581 gctgaaatca cgccacgtca ccatgttgtc tattgccggt gttatcggcg caagtctgtt
     5641 tgtcggttca agcgtcgcca tcgccgaagc gggcccggcg gtattactgg cctatctgtt
     5701 cgccggatta ctggtggtta tgattatgcg gatgttggcg gaaatggcag ttgccacgcc
     5761 cgataccggt tcgttttcca cctatgccga caaggcaatt ggccgctggg cgggttatac
     5821 catcggctgg ctgtactggt ggttttgggt actggttatc ccgctggaag ccaacatcgc
     5881 cgctatgatc ctgcactcgt gggttccagg cattcccatc tggttatttt ccctcgtcat
     5941 taccctcgcc ttaactggca gtaatttatt aagcgttaaa aactacggcg aatttgagtt
     6001 ctggctggcg ctgtgcaaag tcatcgctat cctggccttt attttccttg gtgcagtcgc
     6061 aattagcggt ttttaccctt atgccgaagt gagcgggatc tcaagattgt gggatagcgg
     6121 cggctttatg cccaacggtt tcggtgcggt attaagcgcg atgttgatca ccatgttctc
     6181 gtttatgggc gcagaaattg tcaccattgc cgccgcggaa tccgacacgc cggaaaaaca
     6241 tattgtccgc gccaccaact cggttatctg gcgtatttct atcttctatt tgtgctctat
     6301 ttttgtcgta gtggcgttaa taccgtggaa tatgccgggg ctgaaagccg ttggttctta
     6361 tcgctcggta ctggaattgc tcaatattcc ccatgcgaaa ttaatcatgg actgcgtgat
     6421 attactttcc gtaaccagtt gcctgaactc ggcgctgtat accgcctcaa ggatgctcta
     6481 ctccttaagc cgtcgcggag atgcgcctgc ggtaatgggt aaaatcaacc gcagtaaaac
     6541 cccgtacgtg gcggtgttac tctccaccgg cgcggcattc ttaacggtgg tggtgaacta
     6601 ttacgcgcct gcgaaggtat ttaaatttct gatcgacagc tccggcgcta tcgccctgct
     6661 ggtttattta gtcatcgccg tttcacagtt gcggatgcgc aaaattctgc gagcagaagg
     6721 aagcgaaatt cgcttgcgaa tgtggcttta tccgtggctc acctggctgg tcatcggctt
     6781 tattaccttt gtgttggtag tgatgctatt ccgtccggcg caacagttag aagtgatctc
     6841 caccggctta ttagcgatag ggattatctg taccgtgccg attatggcgc gctggaaaaa
     6901 gctggtattg tggcaaaaaa cacccgttca taatacgcgc tgataatgat caggagtcac
     6961 accatgacca ttacgtctct ggatggctat cgctggctga agaacgatat tattcgcggt
     7021 aattttcaac cggatgaaaa attacgaatg agtttgctga catcgcgtta tgcacttggc
     7081 gttgggccgt tacgggaagc tctttcgcaa ctggtggcgg aacggctggt cacggtggtg
     7141 aatcaaaaag ggtatcgggt ggcgtctatg tcagagcagg agctgctcga tattttcgac
     7201 gcccgcgcca atatggaagc gatgctggtc agtctggcga ttgcccgcgg tggcgatgaa
     7261 tgggaggcag acgttctcgc aaaagcgcat ctgctgagta agctggaggc ctgtgacgcc
     7321 agcgagaaaa tgcttgatga gtgggatctg cgtcatcagg cgtttcatac agcaattgtg
     7381 gcgggctgtg gttctcacta tttgctgcaa atgcgtgaac ggttgtttga tctggcggcg
     7441 cgctatcgat ttatctggct gcggcgaacg gtgctttcgg tagaaatgct ggaggataaa
     7501 cacgatcagc accagaccct gactgcggcg gtactggcgc gagataccgc gcgcgccagt
     7561 gagttaatgc gccagcattt actgacgcca attcccatta tccagcaggc gatggctggc
     7621 aattaactac tcttccggaa tacgcaacac ttgccccgga taaattttat ccgggctttt
     7681 tagcatcggt ttattcgctt cgaagatttt attgtacaga ttagcgttac cgtagacctg
     7741 tttggaaatg gcactcagag tgtcgccaga cttaacggta taaaactggc tggcagtggc
     7801 tggtgtcgcc gttttcacct gatcatcaac actggcaata ccggaaatat tccccaccgc
     7861 aacaaggatt ttctccttcg cctcctgact caggccgtca ccagtgaccg tcgctttgcc
     7921 gtcggcaatt tgaatgttca ctttatcggc atcaggtata ccggttttgc tcagatgctc
     7981 ctgcaccttc ttcgcctgat cgtctttatc gtgctgacct gtaaccgcgt cccagagttt
     8041 ttctccggca tctttcacaa aattgaacag acccatagct acctcattcg ttaacggaaa
     8101 cactcagaaa gtgtagcaga ggaacgcggc gcgttaacgc cgcgggggtg agcacaggtt
     8161 taatcgcggg tttgcaccca gaacgcgtga atcaaaccgg ggatataccc aagcagtgtc
     8221 agcagaatat taataatgaa cgcccaaccg aaccctttac cgagcagcac gccgagaggc
     8281 ggcagaatga tggtgatgac gattctccag aaacccatat gtactcccta taagaaaatt
     8341 actcattgtt taaaaagaga ttttatctct taagcgtagt aa
//
LOCUS       DAPGUL010000167         8378 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.170, whole genome shotgun sequence.
ACCESSION   DAPGUL010000167 DAPGUL010000000
VERSION     DAPGUL010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8378
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.170"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..250
                     /locus_tag="RHX21_004302"
     CDS             <1..250
                     /locus_tag="RHX21_004302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001389100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type IV toxin-antitoxin system YeeU family
                     antitoxin"
                     /protein_id="HDV1989399.1"
                     /translation="FSDADAYHLDQAFPLLMKQLELMLTSGELNPRHQHTITLYAKGL
                     TCEADTLGSCSFVYMAVYATRFSNQLPKASVHQLTHYF"
     gene            559..711
                     /locus_tag="RHX21_004303"
     CDS             559..711
                     /locus_tag="RHX21_004303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001316510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989400.1"
                     /translation="MHSLMNSQARDTRDRSLNDDNVLEISEPCIRSTFERLYQNMNEV
                     FGLGDY"
     gene            complement(791..2038)
                     /locus_tag="RHX21_004304"
     CDS             complement(791..2038)
                     /locus_tag="RHX21_004304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide MFS transporter"
                     /protein_id="HDV1989401.1"
                     /translation="MALNIPFRNAYYRFASSYSFLFFISWSLWWSLYAIWLKGHLGLT
                     GTELGTLYSVNQFTSILFMMFYGIVQDKLGLKKPLIWCMSFILVLTGPFMIYVYEPLL
                     QSNFSVGLILGALFFGLGYLAGCGLLDSFTEKMARNFHFEYGTARAWGSFGYAIGAFF
                     AGIFFSISPHINFWLVSLFGAVFMMINMCFKDKDHQCVAADAGGVKKEDFIAVFKDRN
                     FWVFVIFIVGTWSFYNIFDQQLFPVFYAGLFESHDVGTRLYGYLNSFQVVLEALCMAI
                     IPFFVNRVGPKNALLIGVVIMALRILSCALFVNPWIISLVKLLHAIEVPLCVISVFKY
                     SVANFDKRLSSTIFLIGFQIASSLGIVLLSTPTGILFDHAGYQTVFFAISGIVCLMLL
                     FGIFFLSKKREQIVMETPVPSAI"
     gene            complement(2110..3024)
                     /locus_tag="RHX21_004305"
     CDS             complement(2110..3024)
                     /locus_tag="RHX21_004305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoimidazole riboside kinase"
                     /protein_id="HDV1989402.1"
                     /translation="MSAKVWVLGDAVVDLLPESDGRLLPCPGGAPANVAVGISRLGGT
                     SGFIGRVGDDPFGALMQRTLLTEGVDITYLKQDEWHRTSTVLVDLNDQGERSFTFMVR
                     PSADLFLETTDLPCWRHGEWLHLCSIALSAEPSRTSAFTAMTAIRHAGGFVSFDPNIR
                     EDLWQDEHLLRLCLRQALQLADVVKLSEEEWRLISGKTQNDRDICALAKEYEIAMLLV
                     TKGAEGVVVCYRGQVHHFAGMSVDCVDSTGAGDAFVAGLLTGLSSTGLSTDEREMRRI
                     IDLAQRCGALAVTAKGAMTALPCRQELE"
     gene            3240..4673
                     /gene="cscA"
                     /locus_tag="RHX21_004306"
     CDS             3240..4673
                     /gene="cscA"
                     /locus_tag="RHX21_004306"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HDV1989403.1"
                     /translation="MTQSRLHAAQNALAKLHERRGNTFYPHFHLAPPAGWMNDPNGLI
                     WFNDRYHAFYQHHPMSEHWGPMHWGHATSDDMIHWQHEPIALAPGDDNDKDGCFSGSA
                     VDDNGVLSLIYTGHVWLDGAGNDDAIREVQCLATSRDGIHFEKQGVILTPPEGIMHFR
                     DPKVWREADSWWMVVGAKDPGNTGQILLYRGSSLREWTFDRVLAHADAGESYMWECPD
                     FFSLGDQHYLMFSPQGMNAEGYSYRNRFQSGVIPGMWSPGRLFAQSGHFTELDNGHDF
                     YAPQSFVAKDGRRIVIGWMDMWESPMPSKREGWAGCMTLARELSESNGKLLQRPVHEA
                     ESLRQQHQSISPRTISNKYVLQENAQAVEIQLQWALKNSDAEHYGLQLGTGMRLYIDN
                     QSERLVLWRYYPHENLDGYRSIPLPQRDTLALRIFIDTSSVEVFINDGEAVMSSRIYP
                     QPEERELSLYASHGVAVVQHGALWQLG"
     gene            complement(4681..5739)
                     /locus_tag="RHX21_004307"
     CDS             complement(4681..5739)
                     /locus_tag="RHX21_004307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDV1989404.1"
                     /translation="MDLASDVCFCYSARFTANGLDMASLKDVARLAGVSMMTVSRVMH
                     NAESVRPATRDRVLQAIQTLNYVPDLSARKMRAQGRKPSTLAVLAQDTATTPFSVDIL
                     LAIEQTASEFGWNSFLINIFSEDDAARAARQLLAHRPDGIIYTTMGLRHITLPESLYG
                     ENIVLANCVADDPALPSYIPDDYTAQYESTQHLLAAGYRQPLCFWLPESALATGYRRQ
                     GFEQAWRDAGRDLAEVKQFHMATGDDHYTDLASLLNDHFKSGKPDFDVLICGNDRAAF
                     VAYQVLLAKGVRIPQDVAVMGFDNLVGVGHLFLPPLTTIQLPHDIIGREAALHIIEGR
                     EGGSVTRIPCPLLIRCST"
     gene            5907..6125
                     /locus_tag="RHX21_004308"
                     /pseudo
     CDS             5907..6125
                     /locus_tag="RHX21_004308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416866.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine transporter DsdX"
     gene            6143..7471
                     /gene="dsdA"
                     /locus_tag="RHX21_004309"
     CDS             6143..7471
                     /gene="dsdA"
                     /locus_tag="RHX21_004309"
                     /EC_number="4.3.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine ammonia-lyase"
                     /protein_id="HDV1989405.1"
                     /translation="MENAKMNSLIAQYPLVKDLVALKETTWFNPGTTSLAEGLPYVGL
                     TEQDVQDAHARLSRFAPYLAKAFPETAATGGIIESELVAIPAMQKRLEKEYQQPISGQ
                     LLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLDDDYSKLLSPEFKQFFSQ
                     YSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGV
                     AVEEGRKAAQSDPNCFFIDDENSRTLFLGYSVAGQRLKAQFAEQGRIVDADNPLFVYL
                     PCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGLHDQISVQDIGIDNL
                     TAADGLAVGRASGFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMA
                     GPQRVCASVSYQQMHGFSAEQLRNATHLVWATGGGMVPEEEMEQYLAKGR"
     gene            complement(7580..>8378)
                     /gene="emrY"
                     /locus_tag="RHX21_004310"
     CDS             complement(7580..>8378)
                     /gene="emrY"
                     /locus_tag="RHX21_004310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="multidrug efflux MFS transporter permease
                     subunit EmrY"
                     /protein_id="HDV1989406.1"
                     /translation="SLISLVIWESTSENPILDLSLFKSRNFTIGIVSITCAYLFYSGA
                     IVLMPQLLQETMGYNAIWAGLAYAPIGIMPLLISPLIGRYGNKIDMRLLVTFSFLMYA
                     VCYYWRSVTFMPTIDFTGIILPQFFQGFAVACFFLPLTTISFSGLPDNKFANASSMSN
                     FFRTLSGSVGTSLTMTLWGRRESLHHSQLTATIDQFNPVFNSSSQIMDKYYGSLSGVL
                     NEINNEITQQSLSISANEIFRMAAIAFILLTVLVWFAKPPFTAKGVG"
BASE COUNT         2359 a         2072 c         1933 g         2014 t
ORIGIN      
        1 gttcagcgat gcggatgcat accatctgga ccaggccttt ccactgctga tgaaacaact
       61 ggaactcatg ctcaccagcg gtgaactgaa tccccgccat cagcatacca tcacgctgta
      121 tgcaaaaggg ctgacctgtg aagctgatac tctcggcagt tgtagtttcg tttatatggc
      181 tgtttatgct acccgattct caaatcaatt accgaaagct tctgttcatc aactaactca
      241 ttacttttaa tgatggggcc ctttctgggg cccaagaaat taacaacgct aacaaacaac
      301 ataaataaca ataaattaaa taaaaaattt cattcctgca gggacaccag atacccttca
      361 aacgaaatct accttcaccc cgtaaaagat gggtttggca gcacacttgc cctatatcta
      421 ctcattttta ctgcaacagg ttgaaatctc agcactgtca gaaagcgctg atgactaaac
      481 agccttgggc cgggcgatgt aaccatcaca cagaatcctg atagcgaaat atggcgtgac
      541 tcgatacttc actccgcaat gcattccttg atgaattcgc aggcccgtga tacacgcgac
      601 aggtcgctga atgacgacaa tgtcctggaa atcagcgaac cgtgtatccg gagtacattt
      661 gagcgactgt accagaacat gaatgaggtg tttggattag gcgattatta gcagggctaa
      721 gcattttact attattattt tccggttgag ggatatagag ctatcgacaa caaccggaaa
      781 aagtttacgt ctatattgct gaaggtacag gcgtttccat aactatttgc tcgcgttttt
      841 tactcaggaa gaaaatgcca aatagcaaca tcaggcagac aatacccgaa attgcgaaga
      901 aaactgtctg gtagcctgcg tggtcaaaga gtatcccagt cggcgttgaa agcagcacaa
      961 tcccaagcga actggcaatt tgaaaaccaa tcagaaagat cgtcgacgac aggcgcttat
     1021 caaagtttgc cacgctgtat ttgaagacgg atatgacaca aagtggaacc tcaatggcat
     1081 gtaacagctt cactaatgaa ataatccagg ggttaacgaa cagcgcgcag gaaaggatac
     1141 gcaacgccat aatcacaaca ccgataagta atgcattttt tggccctacc cgattcacaa
     1201 agaacggaat aatcgccatg cacagcgctt cgagtaccac ctggaatgag ttgagataac
     1261 catacaggcg cgttcctaca tcgtgtgatt cgaataaacc tgcataaaag acaggaaaaa
     1321 gttgttgatc aaaaatgtta tagaaagacc acgtcccaac aataaatatg acgaaaaccc
     1381 agaagtttcg atccttgaaa actgcgataa aatcctcttt ttttacccct cccgcatccg
     1441 ccgctacgca ctggtgatcc ttatctttaa aacacatgtt gatcatcata aatacagcgc
     1501 caaatagcga gaccaaccag aagttgatat ggggactgat actaaaaaat atgccggcaa
     1561 agaacgcgcc aatagcatag ccaaaagatc cccaggcgcg cgctgttcca tattcgaaat
     1621 gaaaatttcg cgccattttt tcggtgaagc tgtcaagcaa accgcatccc gccagatacc
     1681 ccaggccaaa aaagagcgcc cccagaatta aacctacaga aaaattgctt tgcagtaacg
     1741 gttcataaac gtaaatcata aacggtccgg tcaagaccag gataaaactc atacaccaga
     1801 tgagcggttt cttcagaccg agtttatcct gaacgatgcc gtagaacatc ataaatagaa
     1861 tgctggtaaa ctggttgacc gaataaagtg tacctaattc cgtccctgtc aaccctagat
     1921 gtcctttcag ccaaatagcg tataacgacc accacagcga ccaggaaata aaaaagagaa
     1981 atgagtaact ggatgcaaaa cgatagtacg catttctgaa tggaatattc agtgccataa
     2041 ttacctgcct gtcgttaaaa aattcacgtc ctatttagag ataagagcga cttcgccgtt
     2101 tacttctcac tattccagtt cttgtcgaca tggcagcgct gtcattgccc ctttcgccgt
     2161 tactgcaagc gctccgcaac gttgagcgag atcgataatt cgtcgcattt ctctctcatc
     2221 tgtagataat cctgtagagg acagacctgt gagtaacccg gcaacgaacg catctcccgc
     2281 ccccgtgcta tcgacacaat ccacagacat tccagcaaaa tggtgaactt gtcctcgata
     2341 gcagaccacc accccttctg cacctttagt caccaacagc atggcgatct catactcttt
     2401 tgccagggcg catatatccc gatcgttctg tgtttttcca ctgattagtc gccattcttc
     2461 ttccgagagc ttgacgacat ccgccagttg tagcgcctgc cgcaaacaca agcggagcaa
     2521 atgctcgtct tgccatagat cttcacgaat attgggatcg aagctgacaa aacctccggc
     2581 atgccggatc gccgtcatcg cagtaaatgc gctggtacgc gaaggctcgg cagacaacgc
     2641 aattgaacag agatgtaacc attcgccatg tcgccagcag ggcaagtctg tcgtctctaa
     2701 aaaaagatcg gcactggggc ggaccataaa cgtaaatgaa cgttcccctt gatcgttcag
     2761 atcgacaagc accgtggatg tccggtgcca ttcatcttgc ttcagatacg tgatatcgac
     2821 tccctcagtt agcagcgttc tttgcattaa tgcaccaaaa ggatcatccc ccacccgacc
     2881 tataaaccca cttgttccgc ctaatctgga gattcccacc gcaacgttag ctggcgcgcc
     2941 gccaggacaa ggcagtaggc gcccgtctga ttctggcaag agatctacga ccgcatcccc
     3001 taaaacccat actttggctg acattttttt cccttaaatt catctgactt acgcatagtg
     3061 ataaacctct ttttcgcaaa atcgtcatgg atttactaaa acatgcatat tcgatcacaa
     3121 aatgtcatag ttaacgttaa catttgtgat attcatcgca tttatgaaag taagggactt
     3181 tatttttata aaagttaacg ttaacaattc accaaatttg cttaaccagg atgataaaaa
     3241 tgacgcaatc tcgattgcat gcggcgcaaa acgcactagc aaaacttcac gagcgccgag
     3301 gtaacacttt ctatccccat tttcacctcg cgcctcctgc cgggtggatg aacgatccaa
     3361 acggcctgat ctggtttaac gatcgttatc acgcgtttta tcaacatcac ccaatgagtg
     3421 aacactgggg gccaatgcac tggggacatg ccaccagcga cgatatgatc cactggcagc
     3481 atgagcctat tgcgctagcg ccaggagacg ataatgacaa agatgggtgt ttttcaggta
     3541 gtgctgtcga tgacaatggt gtcctctcac ttatctacac cggacacgtc tggctcgatg
     3601 gtgcaggtaa tgacgatgca attcgcgaag tacaatgtct ggctaccagt cgggatggta
     3661 ttcatttcga gaaacagggt gtgatcctca ctccaccaga aggaatcatg cacttccgcg
     3721 atcctaaagt gtggcgtgaa gccgactcat ggtggatggt tgtcggggcg aaagacccag
     3781 gcaacacggg gcagatcctg ctttatcgcg gcagttcatt acgtgaatgg actttcgatc
     3841 gcgtactggc ccacgctgat gcgggtgaaa gctatatgtg ggaatgtccg gactttttca
     3901 gccttggcga tcagcattat ctgatgtttt ccccgcaggg aatgaatgcc gagggataca
     3961 gttaccgaaa tcgctttcaa agtggcgtaa tacccggaat gtggtcgcca ggacgacttt
     4021 ttgcacaatc cgggcatttt actgaacttg ataacgggca tgacttttat gcaccacaaa
     4081 gctttgtagc gaaggatggt cggcgtattg ttatcggctg gatggatatg tgggaatcgc
     4141 caatgccctc aaaacgtgaa ggctgggcag gctgcatgac gctggcgcgc gagctatcag
     4201 agagcaatgg caaactccta caacgcccgg tacacgaagc tgagtcgtta cgccagcagc
     4261 atcaatctat ctctccccgc acaatcagca ataaatatgt tttgcaggaa aacgcgcaag
     4321 cagttgagat tcagttgcag tgggcgctga agaacagtga tgccgaacat tacggattac
     4381 agctcggcac tggaatgcgg ctgtatattg ataaccaatc tgagcgactt gttttgtggc
     4441 ggtattaccc acacgagaat ttagacggct accgtagtat tcccctcccg cagcgtgaca
     4501 cgctcgccct aaggatattt atcgatacat catccgtgga agtatttatt aacgacgggg
     4561 aagcggtgat gagtagtcga atctatccgc agccagaaga acgggaactg tcgctttatg
     4621 cctcccacgg agtggctgtg gtgcaacatg gagcactctg gcaactgggt taacataata
     4681 tcaggtggaa caacggatca acagcgggca agggatccgc gtcacacttc ccccttcacg
     4741 accttcaata atatgcaatg cagcttcccg cccgataatg tcatgtggaa gctgaattgt
     4801 ggtcagcggc ggtaaaaaca gatgcccgac gccaaccaga ttatcaaagc ccattacggc
     4861 gacatcctgc gggatacgta cccccttcgc caggagaacc tgataagcca caaaggctgc
     4921 gcgatcgtta ccacatatca gaacatcaaa atctggtttg cccgatttga agtggtcatt
     4981 gagtaaactt gcgagatcgg tgtagtgatc atcacctgtt gccatgtgaa attgtttcac
     5041 ctcagccaga tctcgtccag catcacgcca ggcctgctca aatccctgcc gacgataccc
     5101 cgttgccaac gcactttccg gtagccagaa gcataacggt tgacgatagc ccgccgcgag
     5161 caaatgctgt gttgattcat attgtgcagt gtaatcatca gggatataac tgggtaacgc
     5221 tgggtcatcc gccacacagt tcgccaatac aatattttca ccatacagag actcaggcag
     5281 cgtgatatgt cgcagcccca ttgtagtata gataatgcca tccggacggt gagcaagcag
     5341 ctgacgtgcc gcgcgggcag cgtcatcttc agaaaaaata ttgattaaaa aactattcca
     5401 gccgaactcg ctggcggttt gctcaatggc aagcagaata tcaacagaga aaggagtggt
     5461 agcagtgtcc tgcgccagca cggcgagagt cgacggctta cgtccttgag cgcgcatctt
     5521 acgggcggaa agatcaggaa cataattcag ggtctggatt gcctgcaata cgcggtcacg
     5581 cgttgcagga cgcacagatt ctgcattatg catcacccgg gagactgtca tcatcgacac
     5641 tcccgccagg cgtgcgacat cctttaatga agccatatcc aagccgtttg ccgtaaaacg
     5701 ggcactgtag cagaaacaga cgtcactggc gagatccaac gccctatcac ctgacacggc
     5761 aatacaataa aaaataacaa taattgccgg acaattgtcc ccaattccgc ctctgttctc
     5821 gccaacgagt aaccatatag gcaagtaagt aaaacatgcc aactggcatc gccaacctgg
     5881 agaagaaaat ataaatatgg atcattgtgc tgccgctgta tcccgacatc agcccggaaa
     5941 ttattgcgat tgctatcggt tcaggcgcga ttggctgcac gatcgttacg gactcgcttt
     6001 tctggctggt gaagcaatat tgcggcgcta cgctcaatga aacatttaaa tactatacga
     6061 cagcgacatt tatcgcttca gtcgtcgctc tggcgggcac attcctgctg tcatttatca
     6121 tctaagcgca aagagacgta ctatggaaaa cgctaaaatg aactcgctca tcgcccagta
     6181 tccgttggta aaggatctgg ttgctcttaa agaaaccacc tggtttaatc ctggcacgac
     6241 ctcattggct gaaggtttac cttatgttgg cctgaccgaa caggatgttc aggacgccca
     6301 tgcgcgctta tcccgttttg caccctatct ggcaaaagca tttcctgaaa ctgctgccac
     6361 tggggggatt attgaatcag aactggttgc cattccggct atgcaaaaac ggctggaaaa
     6421 ggaatatcaa caaccgatca gcgggcaact gttactgaaa aaagatagcc atttgcccat
     6481 ttccggctcc ataaaagcac gcggcgggat ttatgaagtc ctggcacacg cagaaaaact
     6541 ggctctggaa gcggggttgc tgacgcttga tgatgactac agcaaactgc tttctccgga
     6601 gtttaaacag ttctttagcc aatacagcat tgctgtgggc tcaaccggaa atctggggtt
     6661 atcaatcggc attatgagcg cccgcattgg ctttaaggtg acagtgcata tgtctgctga
     6721 tgcccgggca tggaaaaaag cgaaactgcg cagccatggc gttacggtcg tggaatatga
     6781 gcaagattat ggtgttgccg tcgaggaagg acgtaaagca gcgcagtctg acccgaactg
     6841 tttctttatt gatgacgaaa attcccgcac gttgttcctt gggtattccg tcgctggcca
     6901 gcgtcttaaa gcgcaatttg ccgagcaagg tcgtatcgtc gatgctgata accctctgtt
     6961 tgtctatctg ccgtgtggtg ttggcggtgg tcctggtggc gtcgcattcg ggcttaaact
     7021 ggcgtttggc gatcatgttc actgcttttt tgccgaacca acgcactccc cttgtatgtt
     7081 gttaggcgtc catacaggat tacacgatca gatttctgtt caggatattg gtatcgacaa
     7141 ccttaccgca gcggatggcc ttgcagttgg tcgcgcatca ggctttgtcg ggcgggcaat
     7201 ggagcgtctg ctggatggct tctataccct tagcgatcaa accatgtatg acatgcttgg
     7261 ctggctggcg caggaagaag gtattcgtct tgaaccttcg gcactggcgg gtatggccgg
     7321 acctcagcgc gtgtgtgcat cagtaagtta ccaacagatg cacggtttca gcgcagaaca
     7381 actgcgtaat gccactcatc tggtgtgggc gacgggaggt ggaatggtgc cggaagaaga
     7441 gatggagcaa tatctggcaa aaggccgcta attaattttc aatgcagcat cgccatcctt
     7501 tccctgggtg agcgatgctg ccgatggcgc aggcttaaga ttctaccgtc ttacctgcta
     7561 tagctctctc tttttaccat cacccaacac ctttcgctgt aaacggcggt ttcgcaaacc
     7621 aaaccaatac cgtaagtaag ataaaagcaa tagccgccat acggaaaatc tcatttgcag
     7681 aaattgaaag tgactgctga gttatttcat tattaatttc attaagaacc cctgaaagcg
     7741 aaccatagta tttatccata atttgtgacg atgaattaaa cacggggtta aattgatcga
     7801 tggttgctgt caactgacta tggtgtaatg attctcggcg tccccacagc gtcattgtca
     7861 acgacgtacc aactgatcct gacaaggtac gaaaaaaatt actcatactc gaggcattgg
     7921 caaatttatt atctggcaaa cctgaaaacg aaatcgttgt taagggtaaa aagaaacagg
     7981 cgacggcgaa tccctgaaaa aactgtggca aaatgatgcc tgtaaaatca atcgttggca
     8041 taaatgtcac agaacgccag taatagcaaa ccgcatacat taaaaaacta aatgtcacca
     8101 acaaccgcat atcaattttg ttgccataac gtcctatcaa aggtgatatt aatagcggca
     8161 tgatgccgat gggcgcatag gcaagtccgg cccatatcgc attatacccc atcgtttcct
     8221 ggagtaactg cggcataagg actatcgccc cagagtaaaa taaatatgcg catgtgatac
     8281 tcacaatacc aatggtgaaa ttacgggact taaacaaact gagatcaaga atcgggttct
     8341 ctgaggtcga ctcccaaatg actaaagaga tcagagaa
//
LOCUS       DAPGUL010000168         8348 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.171, whole genome shotgun sequence.
ACCESSION   DAPGUL010000168 DAPGUL010000000
VERSION     DAPGUL010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8348
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.171"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(85..291)
                     /locus_tag="RHX21_004311"
     CDS             complement(85..291)
                     /locus_tag="RHX21_004311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbfA family protein"
                     /protein_id="HDV1989407.1"
                     /translation="MELYREYPAWLIFLRRTYAVAAGVLALPFMLFWKDRARFYSYLH
                     RVWSKTSDKPVWMDQAEKATGDFY"
     gene            604..693
                     /gene="kdpF"
                     /locus_tag="RHX21_004312"
     CDS             604..693
                     /gene="kdpF"
                     /locus_tag="RHX21_004312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HDV1989408.1"
                     /translation="MSAGVITGVLLVFLLLGYLVYALINAEAF"
     gene            693..2366
                     /gene="kdpA"
                     /locus_tag="RHX21_004313"
     CDS             693..2366
                     /gene="kdpA"
                     /locus_tag="RHX21_004313"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HDV1989409.1"
                     /translation="MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTTGVER
                     VLFRALGVSDREMNWKQYLCAILGLNMLGLAVLFFMLLGQHYLPLNPQQLPGLSWDLA
                     LNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSM
                     STLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFQPYQAVNTVEGAQQLLPMGP
                     VASQEAIKMLGTNGGGFFNANSSHPFENPTALTNFVQMLAIFLIPTALCFAFGEVTGD
                     RRQGRMLLWAMSVIFVICVGVVMWAEVQGNPHLLALGADSSINMEGKESRFGVLVSSL
                     FAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVF
                     IAGLMIGRTPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGP
                     HGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLAFCMFVGRFGVIIPVMAIAGSLV
                     SKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS"
     gene            2389..4437
                     /gene="kdpB"
                     /locus_tag="RHX21_004314"
     CDS             2389..4437
                     /gene="kdpB"
                     /locus_tag="RHX21_004314"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HDV1989410.1"
                     /translation="MSRKQLALFEPTLVVQALKEAVKKLNPQAQWRNPVMFIVWIGSL
                     LTTCISIAMASGAMPGNALFSAAISGWLWVTVLFANFAEALAEGRSKAQANSLKGVKK
                     TAFARKLREPKYGAAADKVPADQLRKGDIVLVEAGDIIPCDGEVIEGGASVDESAITG
                     ESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMVEGAQRRKTPNE
                     IALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGV
                     AGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASEFIPAQGVDEKTLA
                     DAAQLASLADETPEGRSIVILAKQRFNLRERDVQSLHATFVPFTAQSRMSGINIDNRM
                     IRKGSVNAIRRHVEANGGHFPTDVDQKVDQVARQGATPLVVVEGSRVLGVIALKDIVK
                     GGIKERFAQLRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQA
                     EGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGK
                     QMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNIMRLHSPDSAILSAVIFN
                     ALIIVFLIPLALKGVSYKPLTASAMLRRNLWIYGLGGLLVPFIGIKVIDLLLTVCGLV
                     "
     gene            4446..5018
                     /gene="kdpC"
                     /locus_tag="RHX21_004315"
     CDS             4446..5018
                     /gene="kdpC"
                     /locus_tag="RHX21_004315"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HDV1989411.1"
                     /translation="MRGLRPALSTFIFLLLITGGVYPLLTTVLGQWWFPWQANGSLIR
                     EGDTVRGSALIGQNFTGNGYFQGRPSATAEMPYNPQASGGSNLAVSNPELDKQIAARV
                     AALRAANPDASTNVPVELVTASASGLDNNITPQAAVWQIPRVAKARNLSVEQLTQLIA
                     KYSQQPLVKYIGQPVVNIVELNLALDKLDE"
     gene            5011..7695
                     /gene="kdpD"
                     /locus_tag="RHX21_004316"
     CDS             5011..7695
                     /gene="kdpD"
                     /locus_tag="RHX21_004316"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     KdpD"
                     /protein_id="HDV1989412.1"
                     /translation="MNNEPLRPDPDRLLEQTAAPHRGKLKVFFGACAGVGKTWAMLAE
                     AQRLRAQGLDIVVGVVETHGRKDTAAMLEGLAVLPPKRQAYRGRHISEFDLDAALARR
                     PALILMDELAHSNAPGSRHPKRWQDIEELLEAGIDVFTTVNVQHLESLNDVVSGVTGI
                     QVRETVPDPFFDAADDVVLVDLPPDDLRQRLKEGKVYIAGQAERAIEHFFRKGNLIAL
                     RELALRRTADRVDEQMRAWRGHPGEEKVWHTRDAILLCIGHNTGSEKLVRAAARLASR
                     LGSVWHAVYVETPALHRLPEKKRRAILSALRLAQELGAETATLSDPAEEKAVVRYARE
                     HNLGKIILGRPASRRWWRRETFADRLARIAPDLDQVLVALDEPPARTINNAPDSRSFK
                     DKWRVQIQGCVVAAALCAVITLIAMQWLMAFDAANLVMLYLLGVVVVALFYGRWPSVV
                     ATVINVVSFDLFFIAPRGTLAVSDVQYLLTFAVMLTVGLVIGNLTAGVRYQARVARYR
                     EQRTRHLYEMSKALAVGRSPQDIAATSEQFIASTFHARSQVLLPDDNGKLQPLTHPQG
                     MTPWDDAIAQWSFDKGLPAGAGTDTLPGVPYQILPLKSGEKTYGLVVVEPGNLRQLMI
                     PEQQRLLETFTLLVANAFERLTLTASEEQARMASEREQIRNALLAALSHDLRTPLTVL
                     FGQAEILTLDLASEGSPHARQASEIRQHVLNTTRLVNNLLDMARIQSGGFNLKKEWLT
                     LEEVVGSALQMLEPGLSSPINLSLPEPLTLIHVDGPLFERVLINLLENAVKYAGAQAE
                     IGIDAHVEGENLQLDVWDNGPGLPPGQEQTIFDKFARGNKESAVPGVGLGLAICRAIV
                     DVHGGTITAFNRPEGGACFRVTLPQQTAPELEEFHEDM"
     gene            7692..>8348
                     /gene="kdpE"
                     /locus_tag="RHX21_004317"
     CDS             7692..>8348
                     /gene="kdpE"
                     /locus_tag="RHX21_004317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator KdpE"
                     /protein_id="HDV1989413.1"
                     /translation="MTNVLIVEDEQAIRRFLRTALEGDGMRVYEAETLQRGLLEAATR
                     KPDLIILDLGLPDGDGIEFIRDLRQWSAVPVIVLSARSEESDKIAALDAGADDYLSKP
                     FGIGELQARLRVALRRHSATAAPDPLVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLL
                     AVLLNNAGKVLTQRQLLNQVWGPNAVEHSHYLRIYMGHLRQKLEQDPARPRHFITETG
                     I"
BASE COUNT         1730 a         2175 c         2441 g         2002 t
ORIGIN      
        1 taaatattcc tctgaacatc ttcctgatac aaaaaaccgc cagcgtttcc gctggcggtt
       61 ttcaatgtat tcaaaactca gcaatcaata aaaatcacca gttgcctttt cggcctgatc
      121 catccacacc ggtttatcgc tggttttcga ccagacgcga tgcaggtagc tgtaaaagcg
      181 ggcgcggtct ttccagaaaa gcatgaaagg cagcgccaga acgcccgctg caaccgcata
      241 agtacggcgt aaaaagataa gccatgcagg atattctctg tagagttcca tacttttctc
      301 ccccttttgt atctacccgg tgaatggcac cggaaaaatg aatttgttta tctgatgaaa
      361 atagtaccgc cttttgtgta attttactac tcatccgacc acttattttt gcttattgat
      421 ggtttattta cattcatcct gtaattaagt tacacaaaag ttaaattaat actaaacatt
      481 agttaaatca tggcttttgc catttttata ctttttttac accccgcccg cagatttttg
      541 cgaaatcttt gcagccagaa ttctaccctt ccggtatcac ttttaggcca ctggaggtgc
      601 actgtgagtg caggcgtgat aaccggcgta ttgctggtgt ttttattact gggttatctg
      661 gtttatgccc tgatcaatgc ggaggcgttc tgatggctgc gcaagggttc ttactgatcg
      721 ccacgttttt actggtgtta atggtgctgg cgcgtccttt aggcagcggg ctggcgcggc
      781 tgattaatga cattcctctt cccggtacaa cgggcgttga gcgcgtactt tttcgcgcac
      841 ttggcgtctc tgaccgtgag atgaactgga agcaatatct ttgtgccatt ctcggcctga
      901 acatgctggg gctggcggtg ctgtttttta tgttgctcgg tcagcactat ctgccgctta
      961 atccacagca gttgccgggg ctgtcgtggg atctggcgct gaataccgcc gtcagctttg
     1021 tcacgaatac caactggcaa tcttacagcg gtgaaaccac gttgagctat ttcagccaga
     1081 tggctggctt aacggtgcaa aactttcttt ctgccgccag cgggattgcg gtgatttttg
     1141 ccctcatccg tgcgtttacc cgccagagca tgagcacact cgggaatgcc tgggtcgatc
     1201 tgctacgcat cacgttatgg gtgctcgtcc ctgtggcgtt gttgatcgca ctgtttttta
     1261 ttcaacaagg tgcgctgcaa aactttcagc cttatcaggc tgtgaatacc gttgaaggag
     1321 cgcaacagct gttacccatg gggcctgtag cttctcagga agcgatcaag atgctcggta
     1381 ctaacggcgg tggcttcttt aatgccaact cgtcgcatcc gtttgaaaac ccaaccgcac
     1441 tgaccaactt cgtgcagatg ctggcgatct tcttgatccc aacggcgctg tgctttgcct
     1501 ttggtgaagt gacgggcgat cgccgccagg ggcgcatgtt gctgtgggcg atgtcagtga
     1561 tttttgtcat ctgcgtaggc gtggtgatgt gggcagaagt tcagggtaat cctcatctgc
     1621 tggcgctcgg cgcagacagc agcatcaata tggaaggtaa agagagccgt ttcggcgtgc
     1681 tggtcagtag cctgtttgcg gtcgtgacta cggcggcttc ctgtggcgcg gtgattgcga
     1741 tgcatgattc gtttaccgct ctcggtggca tggtgccgat gtggctgatg caaattggtg
     1801 aagtggtgtt cggcggtgtc ggttctggtc tttacggcat gatgctgttt gtcctgctgg
     1861 cggtgtttat tgccgggctg atgattggtc gtacaccgga atatctgggt aaaaaaatcg
     1921 acgtacgcga gatgaaactg actgcactgg cgattctggt taccccgacg ctggtgctga
     1981 tgggcgcggc gctggcaatg atgaccgacg ccggacgtag cgccatgctc aaccctggcc
     2041 cgcatggttt tagcgaagtg ctgtacgccg tgtcatccgc cgctaacaac aacggcagcg
     2101 cctttgccgg attaagcgcc aactccccgt tctggaactg tttactggcg ttctgcatgt
     2161 ttgtcggtcg cttcggggtg attatcccgg tgatggcaat tgccggttcg ctggtgagta
     2221 aaaagagcca acccgccagc tccggcacgc tgccaacgca cggcccgctg tttgttggcc
     2281 tgttaatcgg caccgtgttg ctggttggcg cactgacctt tatccctgcc ctggcgcttg
     2341 gtccggtggc ggaatatctc tcctgatgat attgagtgag cactgaatat gagtcgtaaa
     2401 caactggcgc tattcgaacc aacacttgtc gttcaggcgc tgaaagaagc ggtgaaaaaa
     2461 ttaaacccgc aggcgcaatg gcgcaatccg gtgatgttta tcgtctggat cggcagtctg
     2521 ctgaccacct gtattagcat cgcgatggca agcggtgcga tgcctggcaa tgcgctgttt
     2581 agcgcggcaa ttagcggctg gctgtgggtc accgtactgt tcgctaattt cgccgaggcg
     2641 ctggcagaag gccgcagtaa agcgcaggcc aacagtctta aaggggtgaa aaaaactgcc
     2701 tttgcccgca agctgcgtga gccgaaatat ggcgctgcgg cggacaaagt tcctgccgat
     2761 caactgcgta aaggtgacat cgtgctggta gaagctggcg atattatccc ctgcgatggt
     2821 gaagtcattg aaggcggcgc atcggtcgat gaaagcgcca tcaccgggga atcggcaccg
     2881 gtgatccgtg aatccggcgg cgattttgcc tccgtcaccg gcggcacgcg tattctttct
     2941 gactggctgg tgattgagtg tagcgttaac cccggtgaga catttctgga tcggatgatc
     3001 gcgatggtgg aaggcgcaca gcgacgcaaa acaccgaacg agattgccct gactatcctg
     3061 ctgattgctc tgaccatcgt ctttttactg gcaaccgcca cgctgtggcc gttttccgcg
     3121 tggggcggta atgccgtgag tgtaacggta ctggtggcgc tgctggtctg tctgatccca
     3181 accactattg gcggcctgtt gtcagcgatc ggcgtcgccg ggatgagtcg gatgctgggc
     3241 gcgaatgtga ttgccaccag cggacgtgca gttgaagcgg caggtgacgt tgacgttctg
     3301 ctactggata aaaccggcac catcacactc ggtaaccgtc aggcgtcgga gtttatccct
     3361 gcgcagggcg tggatgaaaa aacgctggct gacgccgcac aactggcttc gctggctgat
     3421 gaaacgccgg aaggccgcag tattgtgatc ctcgccaagc aacgttttaa cctgcgcgag
     3481 cgcgatgtgc agtcgctcca tgccaccttt gtaccgttta ctgcgcaaag ccggatgagc
     3541 gggatcaaca tcgacaaccg catgatccgt aaaggttctg tcaatgccat tcgccgccat
     3601 gttgaggcta acggcggtca cttccctacc gatgttgatc aaaaagtcga tcaggttgcg
     3661 cgtcaggggg ccacgccgct ggtggtggtg gaaggttccc gtgtgctggg cgttattgcg
     3721 ctgaaagata tcgtcaaagg cggtattaaa gagcgcttcg cccagctgcg caaaatgggc
     3781 attaaaacgg tgatgattac cggcgataac cgtctgactg ccgccgccat tgctgcggaa
     3841 gcgggcgtcg atgattttct cgccgaagcg acaccggagg ccaagctggc attgattcgt
     3901 cagtatcagg cggaaggccg tttggtggcg atgaccggcg acggcaccaa cgatgctcca
     3961 gcgctggcgc aggcagatgt cgcggtggcg atgaactccg gtactcaggc ggcgaaagaa
     4021 gcgggcaata tggtcgatct cgactctaac ccgaccaagt tgatcgaggt ggtacatatt
     4081 ggcaaacaga tgctgatgac ccgtggctcg ctgaccacct tcagcattgc caacgatgtg
     4141 gcgaaatact tcgccattat tccggcggcg ttcgcggcaa cgtatccgca gttaaatgcg
     4201 ctgaacatca tgcgccttca ttcgcccgac tccgccattc tcagtgcggt cattttcaac
     4261 gccttgatta tcgtcttttt gattcctctg gcgttaaaag gcgtgagtta taaaccgctt
     4321 accgcttctg ccatgttgcg ccgtaactta tggatttacg gtctgggtgg gctgctggtg
     4381 ccgtttattg gtatcaaagt cattgattta ctgctgaccg tttgcggtct ggtgtgaggt
     4441 ttaccatgcg tggcttacgt ccggcattat cgacatttat ctttctgtta ttgattactg
     4501 gcggcgttta cccgctgctg accaccgtgc tggggcaatg gtggtttccc tggcaggcca
     4561 acggttcgtt gattcgtgaa ggtgatacgg tgcggggttc ggcattaatc gggcagaatt
     4621 ttaccggcaa cggctatttt cagggtcgcc cgtcggcaac ggcagaaatg ccctataatc
     4681 cacaggcttc tggcgggagc aatctggcgg tcagtaaccc tgagctggat aaacaaatag
     4741 ccgcacgcgt tgctgcatta cgggccgcta acccggatgc cagtacgaac gttccggttg
     4801 aactggtgac ggcatcggca agcgggctgg acaataatat caccccgcaa gcggcggtct
     4861 ggcaaatccc acgcgtggcg aaagcgcgta atctcagcgt tgaacagctc acgcaactga
     4921 tcgcaaaata cagccaacaa ccgctggtga aatatatcgg ccagccggtc gtcaacattg
     4981 ttgaactcaa tctggcgctg gataaacttg atgaataacg aacccttacg tcccgacccc
     5041 gatcgtctgc tggaacaaac tgccgcgccg catcggggga agctgaaagt tttcttcggt
     5101 gcctgtgcag gcgtcgggaa gacctgggcg atgctggcag aagcccagcg actgcgggcg
     5161 caagggctgg atattgtggt tggcgtggta gaaacccatg ggcggaaaga taccgccgcc
     5221 atgcttgaag ggctggctgt tctgccgccc aaacgccagg cgtaccgtgg gcggcatatc
     5281 agcgagtttg atctcgatgc cgccctcgcc cgccgtccgg cgctgatctt aatggacgaa
     5341 ctggcgcaca gtaatgcgcc aggttctcgt catcctaaac gctggcagga tatcgaagaa
     5401 ctgctggaag ctggcattga tgttttcaca accgtcaacg ttcagcatct ggaaagtctg
     5461 aatgatgtgg tcagcggcgt caccggaatt caggtacggg aaaccgtgcc cgatcctttt
     5521 ttcgatgccg ccgacgacgt agtgctggtg gacttgcccc cggacgatct gcgccagcgg
     5581 ctgaaagaag gcaaagtcta tattgccggg caggcggagc gcgccattga acattttttc
     5641 cgcaaaggca atctgatcgc cctgcgtgaa ctggcactgc gccgtactgc cgatcgcgta
     5701 gatgagcaaa tgcgcgcctg gcgggggcat cctggtgaag agaaagtgtg gcacacgcgc
     5761 gacgcgatcc ttttatgcat cgggcataac accggcagtg agaaactggt ccgcgcggcg
     5821 gcgcggttgg cctcgcgcct gggtagcgtc tggcacgcgg tgtatgttga aacccctgcc
     5881 ctgcatcgct taccggaaaa aaaacgtcgg gcaattctca gcgccttacg tctggcgcag
     5941 gagctgggcg cggagacggc tacactttct gatccagcgg aagaaaaagc agtagtgcgt
     6001 tatgcccgtg aacataatct cggcaagatt attctcggtc gcccggcctc gcgccgctgg
     6061 tggcgtcggg aaacgtttgc tgaccgactg gcgcgcatcg cccccgatct cgatcaggtg
     6121 ctggtcgcgc ttgatgaacc acccgcccgc acgattaaca acgcgccgga tagccgctct
     6181 tttaaagaca agtggcgggt acagattcag ggatgcgtgg ttgccgccgc gttatgcgcc
     6241 gttatcactt taattgccat gcagtggctg atggcgtttg atgccgccaa cctggtgatg
     6301 ctgtatctgc ttggcgtggt ggtggtggcg ctattttatg gacgctggcc ttcggtggtt
     6361 gctaccgtca ttaatgtggt gagtttcgat ctctttttta tcgccccacg cggcacgctc
     6421 gctgtctctg atgtgcaata tctgctgacc ttcgcggtga tgttaaccgt cgggctggtg
     6481 atcgggaacc ttactgcggg tgtgcgttat caggcgcggg tagcccgtta ccgcgagcaa
     6541 cgcacacggc acttatatga aatgtcgaaa gctctggcgg tgggccgcag tccgcaggac
     6601 atcgccgcca ccagcgaaca atttattgcc tccacgtttc atgcccgcag tcaggtgttg
     6661 ttgcccgatg acaacggtaa attgcagccg ttaacacatc cgcaaggaat gaccccgtgg
     6721 gacgatgcca tcgcacagtg gagttttgat aaaggcctgc ctgcgggtgc gggcaccgac
     6781 acgttacccg gtgtaccgta ccagattttg ccgttaaaaa gcggtgagaa aacctacggg
     6841 ctggtggtgg tggaaccagg gaatctgcgt cagttgatga tcccggaaca gcagcgcctg
     6901 ctggagacgt ttacgctgtt agtcgccaat gcgtttgagc ggcttacgct gaccgccagt
     6961 gaagaacagg cgcggatggc aagcgaacgg gaacagatcc gcaacgctct gctggcggcg
     7021 ctttcgcatg atttacgcac gccgctcacg gtgctgttcg gtcaggcaga aatcttaacg
     7081 ctcgatctgg caagcgaagg atcgcctcac gcccgccagg ccagcgagat tcgtcagcac
     7141 gtgctgaaca ctacccgact ggtgaataat ctactggata tggcgcgaat tcagtccggc
     7201 ggctttaatt tgaagaaaga gtggttaacg ctggaagaag tggtcggcag cgcgctgcaa
     7261 atgctggaac cgggtttatc gtcgcccatc aatctttctc tgccagaacc gctgacctta
     7321 atccacgttg acgggccact ctttgaacgg gtgctgatta atctgctgga gaacgcggtg
     7381 aaatatgcgg gtgcgcaggc cgaaattggt atcgatgccc acgttgaggg cgaaaatcta
     7441 caactggatg tctgggataa cggccccggt cttccgccag gccaggagca gacgatattt
     7501 gataagtttg ctcgcgggaa taaagagtcg gcagtaccgg gggtagggct tggactggca
     7561 atttgtcggg cgatagtgga tgtacacggg ggcactatta ccgcgttcaa ccgaccggaa
     7621 ggtggtgcct gttttcgtgt tacacttccc cagcaaactg cccctgaact tgaagaattt
     7681 catgaggata tgtgacaaac gttctgattg ttgaagatga acaggctatt cgtcgctttc
     7741 tgcgcacggc gctggagggc gacgggatgc gcgtctatga ggccgaaacg ctgcaacgcg
     7801 gcttgctgga agcggctacc cgtaagccag atttgattat tctcgatctc ggcctgcccg
     7861 atggtgatgg gattgagttt atccgcgacc tgcgccagtg gagcgcggtg ccggtgattg
     7921 tgctttccgc acgcagcgaa gagagcgaca aaatcgccgc gctggatgcc ggagcggatg
     7981 attatctgag taagccgttt ggcattggcg aattgcaggc ccgtctgcgc gtcgctttac
     8041 gccgccactc cgccaccgcc gcgcccgatc cgctggtgaa attttccgat gttaccgtcg
     8101 atttagccgc ccgcgtgatt caccggggtg aggaagaggt gcatctcacg ccgattgagt
     8161 tccgcctgct ggcggtgctg ctgaataatg ccgggaaagt gctcacccag cgccagttac
     8221 tcaatcaggt gtgggggcca aacgcggtcg aacacagtca ctatttgcgt atttatatgg
     8281 gacatctgcg acaaaaactg gaacaggatc ccgctcgccc ccgccatttc attactgaaa
     8341 ccggtatt
//
LOCUS       DAPGUL010000169         8339 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.172, whole genome shotgun sequence.
ACCESSION   DAPGUL010000169 DAPGUL010000000
VERSION     DAPGUL010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8339
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.172"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..439
                     /locus_tag="RHX21_004318"
     CDS             <1..439
                     /locus_tag="RHX21_004318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989414.1"
                     /translation="NNNFFIQLIDQALRSTDDMIKANAWYLYKEWIRSDDVSPIFIET
                     EEKLRTFNTNKLTRNDNIFILFSSVDDGPVMVVSSQRLHDMLNPTKDTNWNSTYIYKS
                     RHEMLPVNLTQETLFSSKSHGKYALFPIFTASWRAHRIMNKGV"
     gene            662..1159
                     /gene="ubiC"
                     /locus_tag="RHX21_004319"
     CDS             662..1159
                     /gene="ubiC"
                     /locus_tag="RHX21_004319"
                     /EC_number="4.1.3.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709881.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate lyase"
                     /protein_id="HDV1989415.1"
                     /translation="MSHPALTQLRALRYFKEIPALEPQLLDWLLLEDSMTKRFEQQGK
                     TVSVTMIREGFVEQNEIPEELPLLPKESRYWLREILLCADGEPWLAGRTVVPVSTLSG
                     PELALQKLGKTPLGRYLFTSSTLTRDFIEIGRDAGLWGRRSRLRLSGKPLLLTELFLP
                     ASPLY"
     gene            1172..2044
                     /gene="ubiA"
                     /locus_tag="RHX21_004320"
     CDS             1172..2044
                     /gene="ubiA"
                     /locus_tag="RHX21_004320"
                     /EC_number="2.5.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybenzoate octaprenyltransferase"
                     /protein_id="HDV1989416.1"
                     /translation="MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVP
                     QLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVV
                     LVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAA
                     VSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGIL
                     QIGVLALMAIIGELNGLGWGYYWSIVVAGALFVYQQKLIANREREACFKAFMNNNYVG
                     LVLFLGLAMSYWHF"
     gene            complement(2199..4622)
                     /gene="plsB"
                     /locus_tag="RHX21_004321"
     CDS             complement(2199..4622)
                     /gene="plsB"
                     /locus_tag="RHX21_004321"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418465.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsB"
                     /protein_id="HDV1989417.1"
                     /translation="MSGWPRIYYKLLNLPLSILVKSKSIPADPAPELGLDTSRPIMYV
                     LPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGTLLPRYVFIHGGPRVFTYYTPKEESI
                     KLFHDYLDLHRSNPNLDVQMVPVSVMFGRAPGREKGEVNPPLRMLNGVQKFFAVLWLG
                     RDSFVRFSPSVSLRRMADEHGTDKTIAQKLARVARMHFARQRLAAVGPRLPARQDLFN
                     KLLASRAIAKAVEDEARSKKISHEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWN
                     RLYQGINVHNAERVRQLAHDGHELVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGIN
                     LNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTG
                     RLLDPKTGTLSMTIQAMLRGGTRPITLIPIYIGYEHVMEVGTYAKELRGATKEKESLP
                     QMLRGLSKLRNLGQGYVNFGEPMPLMTYLNQHVPDWRESIDPIEAVRPAWLTPTVNNI
                     AADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLNCYLDLMRNVPYSTDST
                     VPSASASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLVLPSLMA
                     AIVTQHRHISRDVLMEHVNVLYPMLKAELFLRWDRDELPDVIDALANEMQRQGLITLQ
                     DDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSANPSINRGTLEKESRTVAQRLS
                     VLHGINAPEFFDKAVFSSLVLTLRDEGYISDSGDAEPAETMKVYQLLAELITSDVRLT
                     IESATQGEG"
     gene            4793..5161
                     /gene="dgkA"
                     /locus_tag="RHX21_004322"
     CDS             4793..5161
                     /gene="dgkA"
                     /locus_tag="RHX21_004322"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDV1989418.1"
                     /translation="MANNTTGFTRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLAVV
                     IACWLDVDAITRVLLISSVMLVMIVEILNSAIEAVVDRIGSEYHELSGRAKDMGSAAV
                     LIAIIVAVITWCILLWSHFG"
     gene            5271..5879
                     /gene="lexA"
                     /locus_tag="RHX21_004323"
     CDS             5271..5879
                     /gene="lexA"
                     /locus_tag="RHX21_004323"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repressor LexA"
                     /protein_id="HDV1989419.1"
                     /translation="MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAE
                     EHLKALARKGVIEIVSGASRGIRLLQEEEEGLPLVGRVAAGEPLLAQQHIEGHYQVDP
                     SLFKPNADFLLRVSGMSMKDIGIMDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKK
                     QGNKVELLPENSEFKPIVVDLRQQSFTIEGLAVGVIRNGDWL"
     gene            5952..7277
                     /gene="dinF"
                     /locus_tag="RHX21_004324"
     CDS             5952..7277
                     /gene="dinF"
                     /locus_tag="RHX21_004324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter DinF"
                     /protein_id="HDV1989420.1"
                     /translation="MAFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSPVY
                     LGGVAVGATATSFLFMLLLFLRMSTTGLTAQAYGAKNPQALARALVQPLLLALGAGAL
                     IALLRTPIIDLALHIVGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARA
                     PVILLVVGNILNIVLDVWLVMGLHMNVQGAALATVIAEYATLLIGLLMVRKILKLRGI
                     SGEMLKTAWRGNFRRLLALNRDIMLRSLLLQLCFGAITVLGARLGSDIVAVNAVLMTL
                     LTFTAYALDGFAYAVEAHSGQAYGARDGSQLLDVWRAACRQSGIVALLFSVVYLLAGE
                     HIIALLTSLTQIQQLADRYLIWQVILPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAA
                     GFALTLLTLPWLGNHGLWLALTVFLALRGLSLAAIWRRHWRNGTWFAAT"
     gene            7393..7602
                     /locus_tag="RHX21_004325"
     CDS             7393..7602
                     /locus_tag="RHX21_004325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HDV1989421.1"
                     /translation="MNKDEAGGNWKQFKGKVKEQWGKLTDDDMTIIEGKRDQLVGKIQ
                     ERYGYQKDQAEKEVVDWETRNEYRW"
     gene            complement(7644..8159)
                     /gene="zur"
                     /locus_tag="RHX21_004326"
     CDS             complement(7644..8159)
                     /gene="zur"
                     /locus_tag="RHX21_004326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418470.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc uptake transcriptional repressor Zur"
                     /protein_id="HDV1989422.1"
                     /translation="MEKTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISA
                     YDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFI
                     CDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEACRHPEQCQH
                     DHSVQVKKKPR"
BASE COUNT         1898 a         2022 c         2263 g         2156 t
ORIGIN      
        1 aaataacaat ttttttatcc aacttatcga tcaggcctta cgatcaacgg atgatatgat
       61 caaagcaaat gcctggtatc tttataaaga gtggattcgt agtgatgatg tttcacctat
      121 atttatagaa actgaagaaa agttaagaac ctttaacact aataaattaa cacgaaacga
      181 taatatattt atcctgttct cctctgtcga tgatgggcct gttatggtgg taagctccca
      241 gcgcttacat gatatgttga atcctacaaa agataccaat tggaattcca cgtatatcta
      301 caaatccaga catgagatgt tgcctgttaa tcttactcag gaaacacttt tcagctccaa
      361 atctcatggt aaatatgcgc ttttccccat ttttactgcg agttggcgag ctcatcgtat
      421 aatgaataag ggtgtttaag taaaggaaaa catcaccgtt cctggcatcc tgggcggtga
      481 tgcccctatg gttgccctct ccagcgcggg catcggcaaa gcgtaaggtt caacagcgtt
      541 ttaccacttc atgcgattgt tgcgtttttg ttgcgtatta gatcacttaa tttgctttac
      601 atctcccgta aacacttttc tgcgatacaa tgcctttacg ttatgtaacg gagagttcgg
      661 catgtcacac cccgcgttaa cgcaactgcg tgcgctgcgc tattttaaag agatccctgc
      721 cctggaaccg caactgctcg actggctgtt gctggaggat tccatgacaa aacgttttga
      781 acagcaggga aaaacggtaa gcgtgacgat gatccgcgaa gggtttgtcg agcagaatga
      841 aatccccgaa gaactgccgc tgctgccgaa agagtctcgt tactggttac gtgaaatttt
      901 gttatgtgcc gatggtgaac cgtggcttgc cggtcgtacc gtcgttcctg tgtcaacgtt
      961 aagcgggccg gagctggcgt tacaaaaatt gggtaaaacg ccgttaggac gctatctgtt
     1021 cacatcatcg acattaaccc gggactttat tgagataggc cgtgatgccg gactgtgggg
     1081 gcgacgttcc cgcctgcgat taagcggtaa accgctgttg ctaacagaac tgtttttacc
     1141 ggcgtcaccg ttgtactaag aggaaaaaaa tatggagtgg agtctgacgc agaataagct
     1201 gctggcgttt catcgcttaa tgcgtacgga taagccaatt ggcgcgttac tgctgctctg
     1261 gccaacatta tgggcgttgt gggtggcgac accgggcgtt cctcagctct ggatcctggc
     1321 ggtatttgtc gcgggtgtct ggctgatgcg cgctgctgga tgtgtggtga atgattatgc
     1381 tgaccgaaag tttgatggtc atgttaagcg cacggcgaac cgaccacttc ccagcggcgc
     1441 ggtaacagag aaagaggcgc gcgcgctgtt tgtagtgctg gtactgattt cgtttttact
     1501 ggtactgacg ctgaatacga tgaccattct gttgtcgatt gccgctctgg cgttggcgtg
     1561 ggtgtacccg tttatgaagc ggtataccca tctcccgcaa gtggtgctgg gcgcggcgtt
     1621 tggctggtcg attccaatgg cttttgccgc tgtgagtgag tcggtgccat tgagttgctg
     1681 gttaatgttc ctcgccaata ttctctgggc ggtggcttac gacacgcagt atgcgatggt
     1741 tgaccgcgat gatgatgtga agattggcat taaatccacg gcaatcctgt tcggccaata
     1801 cgataaattg attattggta ttttgcagat tggcgtactg gcactgatgg cgatcatcgg
     1861 tgagttaaat ggcttaggct ggggatatta ctggtcaatt gtggtggctg gcgcgctgtt
     1921 tgtttatcaa caaaaactga ttgccaaccg cgagcgtgaa gcctgcttta aagcatttat
     1981 gaataataac tatgttggtc tggtactgtt tttaggactg gcaatgagtt actggcattt
     2041 ctgatgatgt aaaaaagccg gatgatcatc cggctttctt ctgggttgcc ttatgcgcgg
     2101 cgcttctcag gcctacacaa cacatcgcaa tttattgaat ttgcagatta tggaaggccg
     2161 gataaggcgt tttcgccgca tccggcaatt ctctctgatt acccttcgcc ctgcgtcgca
     2221 ctctcaatcg tcaaacgcac gtctgatgta atcaactccg ccagcaactg ataaaccttc
     2281 atcgtttctg ccggttcggc gtcgccgcta tcgctgatat acccttcatc acgcagcgtc
     2341 agcaccagag aactgaacac cgccttgtcg aagaactccg gcgcgttgat gccgtgcagc
     2401 acggagagac gttgcgcgac ggtgcggctc tctttctcca gcgtaccgcg gttgatcgac
     2461 gggttggcac tcaacaacca gaaggtgatg gcataacgtt gcagcgtttc gcgcgcgcct
     2521 gcggccagca gctgtagggt gcgagaatgc gccgggttga tatgcaactc atcatcttgc
     2581 agggtaatca gcccctgacg ttgcatctca tttgccagcg catcaataac gtccggcaac
     2641 tcgtcgcgat cccagcgcag gaacagctcc gctttcagca ttgggtaaag cacattgacg
     2701 tgctccatca atacgtcgcg ggagatgtgg cgatgctggg tgacaattgc cgccatcagc
     2761 gaaggcagca ccaacatatg cgcaatgttg ttgcgatagt aggtcatcag caccgcttgc
     2821 tcgcgtggca gaatgatgat gtcgccgata gtgtctttct cgacttcaaa cttgttcatt
     2881 tgcagcgcgt gatcgataag ctcgctggcg ctggctgaag gaacggtaga gtctgtggag
     2941 taaggtacgt tgcgcatcag atccaggtag cagttgagtt gctcggttaa ctgctcgcgg
     3001 gtgagtgagc gctgacgtga tgccagaagc gcagtacaac acaggttcat ggcgtttgcc
     3061 gcgcctgcgt tgttaatgcg taccatcaga tcggcagcaa tattattgac cgtcggcgtt
     3121 aaccaggccg gacgcaccgc ttcgatggga tcgatagatt cacgccagtc tggtacgtgc
     3181 tggttaaggt aggtcatcaa cggcattggt tcaccgaagt tgacgtaacc ctgaccgaga
     3241 ttacgcagct tgcttaaacc gcgcagcatc tgcggcaggc tctctttctc tttcgtcgcg
     3301 ccgcgcagtt ctttggcgta agtacccact tccatgacgt gctcataacc gatatagatc
     3361 ggaatcagcg taatcggacg cgtgccgcca cgcagcatcg cctgaatggt catcgacagc
     3421 gtaccggttt tcggatccag caaacgcccc gtgcgggaac gaccgccttc cacgaagtac
     3481 tcgacggaat aaccacggct gaacagttcg ccgagatact cacggaaaac ggtggaataa
     3541 agtttattgc ctttaaaagt acggcgaata aagaacgccc ccagacggcg gaaaatcggc
     3601 ccggccggcc agaagttcag gttgatcccg gcggcgatat gcggcggcac cagcccctgg
     3661 tggtacagca cgtaagaaag tagcaggtag tccatgtgac tgcggtggca aggcacatac
     3721 accagctcat gaccgtcgtg ggccagctgg cgaacgcgct cggcgttatg gacgttgatg
     3781 ccctgataaa gtcggttcca ggtgaagccc agaatgcggt cagtcaggcg gatcatctcg
     3841 taagagaaat tcgccgcaat ctcttccatc agcgcaatcg cgttctgctg cgctttttca
     3901 tgggagattt ttttgctgcg cgcttcatct tctaccgctt tggcaatggc gcgggaggcg
     3961 agcagcttat taaacagatc ctgacgagca ggcagacgtg ggcccacagc agccagacgt
     4021 tgacgggcaa agtgcatacg cgccacgcgc gccagtttct gtgcgatagt tttatccgtg
     4081 ccgtgttcat ccgccatacg gcgcagcgaa actgacggcg agaaacgcac aaaactgtcg
     4141 cgaccgagcc acagtacggc gaaaaatttc tgtacgccgt taagcatacg cagcggcggg
     4201 tttacttcgc ctttttcacg ccccggcgcg cgaccaaaca tcaccgatac tggcaccatc
     4261 tgcacatcca gatttgggtt gctacggtgc aaatcgagat agtcgtggaa cagcttaata
     4321 gactcttctt tcggcgtgta ataggtgaat acacgcggcc cgccgtgaat gaacacatag
     4381 cgcggcagta gcgtgccgtc gatttccagc ggctctaacg ggtcaggcaa gtcatgagcc
     4441 agacactggg cgcgtaacgt cagcaaatct gctttcgagt tgtacggtaa aacgtacata
     4501 attggacgag aagtatccag ccccagttcc ggggcaggat ctgccggaat agacttgctt
     4561 tttaccagga tgcttaatgg taaattcagt aatttgtagt aaattcgtgg ccagccggac
     4621 ataaacgatg taaagcctct ggttaataat gcaaatgcgc ggcaaggata gcagaaagtc
     4681 atgggaaatt ctgtggtatc cgctcatgtt tcgcgcggcg ttacgcaaac ccgaatcatc
     4741 ggatttaacg gtacactgat attgacgctc ataatgtaaa aaggttcttt caatggccaa
     4801 taataccact ggattcaccc gaattatcaa agctgctggc tattcctgga aaggtttacg
     4861 cgctgcatgg atcaacgaag cggcattccg tcaggaaggc gtagcggtat tgttggcggt
     4921 ggtcatcgcc tgctggctgg atgtggacgc aattacccgc gtgctgctta tcagctccgt
     4981 gatgctggtg atgattgtgg aaattctcaa tagcgccatc gaagcagtgg ttgaccgaat
     5041 tggctctgaa taccatgagc tttccggacg cgctaaagat atgggatccg ccgcggtgct
     5101 gattgccatt atcgtcgccg tgattacctg gtgcattctg ttatggtcgc attttggata
     5161 acccttccag atttcgataa atctctggtt tattgtgcag tttatggttc caaaatcgcc
     5221 ttttgctgta tatactcaca gcataactgt atatacaccc agggggcgga atgaaagcgt
     5281 taacggccag gcaacaagag gtgtttgatc tcatccgtga tcacatcagc cagacaggta
     5341 tgccgccgac gcgtgcggaa atcgcgcagc gtttggggtt ccgttcccca aacgcggctg
     5401 aagaacatct gaaggcgctg gcacgcaaag gcgttattga aattgtttcc ggcgcatcac
     5461 gcgggattcg tctgttgcag gaagaggaag aagggttgcc gctggtaggt cgtgtggctg
     5521 ccggtgaacc gcttctggcg caacagcata ttgaaggtca ttatcaggtc gatccttcct
     5581 tgttcaagcc gaatgctgat ttcctgctgc gcgtcagcgg gatgtcgatg aaagatatcg
     5641 gcattatgga tggtgacttg ctggcagtgc ataaaactca ggatgtacgt aacggtcagg
     5701 tcgttgtcgc acgtattgat gacgaagtta ccgttaagcg cctgaaaaaa cagggcaata
     5761 aagtcgaact gttgccagaa aatagcgagt ttaaaccaat tgtcgttgac cttcgtcagc
     5821 agagcttcac cattgaaggg ctggcggttg gggttattcg caacggcgac tggctgtaac
     5881 atatctctga gaccgcgatg ccgccaggcg tcgcggtttg tttttcatct ctcttcatca
     5941 ggcttgtctg catggcattc ctcacttcat ctgataaagc actctggcat ctcgccttac
     6001 ccatgatttt ctccaatatc accgttccgt tgctgggact ggtcgatacg gcggtaattg
     6061 gtcatcttga tagcccggtt tatttgggcg gcgtggcggt tggtgcaacg gcgaccagct
     6121 ttctctttat gctgttgctg tttttacgca tgagcaccac cgggctgact gcgcaggctt
     6181 atggtgccaa aaatcctcag gcattagccc gtgcgctggt gcaaccgttg ctgttggcgt
     6241 tgggggctgg ggcgttaatt gcgctgctgc gtacaccgat tatcgatctg gcgctgcata
     6301 ttgttggcgg tagtgaagcg gtcctggaac aggcgcggcg ctttcttgaa atccgctggt
     6361 taagcgctcc ggcgtcgctg gcgaatctgg tattactcgg ttggttactc ggcgtgcaat
     6421 atgcccgtgc gccagtaatt ttgttagtgg tcggcaatat cctcaacatt gtgctggatg
     6481 tctggctggt gatggggctg catatgaacg tgcagggcgc ggcgctggcg acggttattg
     6541 cggaatatgc aacattgctg attggtctgc taatggtgcg taaaatcctc aaactacgcg
     6601 gaatttccgg cgaaatgctg aaaactgcct ggcgaggaaa cttccgtcgc ttgctggcgc
     6661 ttaaccgcga tatcatgctg cgttcgctgt tgttgcaact ctgtttcggc gcgatcaccg
     6721 tacttggtgc gcgactgggg agtgacattg tcgctgttaa cgcggttctg atgacgctac
     6781 tcacctttac cgcctatgcg cttgatggtt ttgcctacgc ggttgaagcg cactccggtc
     6841 aggcatacgg tgcgcgcgac ggtagccagt tgctggatgt atggcgggca gcgtgccgcc
     6901 agtcggggat tgtagcgtta ctgttttcgg tggtttattt gctggcaggg gaacacatca
     6961 ttgcgttgct gacgtcgtta acccagattc agcagctggc tgaccgctat cttatctggc
     7021 aggtgatttt gccgttggtt ggcgtctggt gttatctgct ggacggcatg tttataggcg
     7081 caacgcgtgc cgccgaaatg cgtaacagta tggcggtggc cgccgcaggt tttgcgctga
     7141 cgctccttac gctgccgtgg ctgggtaatc atggtttgtg gctggcatta accgtctttc
     7201 tggcgttgcg cgggctttct ctggcggcta tctggcggcg tcactggcgc aacggtacct
     7261 ggtttgccgc aacgtgacgg ttaaaaattc tgaataaatt atcctaagcc aaattgctga
     7321 ctacacttaa tctcacgttc agaagaaaag tgaacgtact ctcattcaca acctaacgat
     7381 gaggtcttga ttatgaataa agatgaagcc ggcggtaact ggaaacagtt taaaggtaaa
     7441 gtgaaagagc aatggggcaa actgaccgat gatgatatga cgatcattga aggtaaacgt
     7501 gatcaactgg tcggtaaaat ccaggaacgt tatggttatc agaaagatca ggcagaaaaa
     7561 gaggtcgtgg attgggaaac ccgcaatgaa tatcgctggt aattaatccc tcctgcccga
     7621 cgtgtacaag gatgtacgcc ctcttaacgc ggtttctttt tcacctgcac agagtgatca
     7681 tgctggcact gttcaggatg acgacacgct tccacttcca cgcatgccgc acagagccca
     7741 tgtgcttcaa tcacattatg ccgcagggca aaccccattt ttgccgccag cgtatgcata
     7801 atgtcttcca cgccttctgc acactcttct ttcaccgcgc cgcagcgatc gcatataaac
     7861 atggctgacg tatgcgtggg ctggtcgaac agatgacaga gcacataact gttggtggat
     7921 tccaccttat gcacaaaacc ttgctcaagc agaaaatcca gcgcgcgata aaccgttggc
     7981 ggcttggctt gcggttcagc ttcgcgcagt aaatcaagca gatcataagc gctgatagcg
     8041 ccatcctgca gactcatcag gcgcaacact tccaggcgct gtggggtcag gcgcacatta
     8101 cgctgcgcgc agattttttc agcctgcgct aataactcct gcgttgtggt cttttccatc
     8161 gggcacctca aagtgggggt taagaatgtc cttactttac catgttccag gaaaaacacc
     8221 gagaaccctt attgttgccg taatgttgat tttctgtttt gtaggtaagg tgttgtgttg
     8281 ccttgtcgta ccattatcaa cacgataata attaataatt catttttaaa taaattgct
//
LOCUS       DAPGUL010000170         8219 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.173, whole genome shotgun sequence.
ACCESSION   DAPGUL010000170 DAPGUL010000000
VERSION     DAPGUL010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8219
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.173"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            276..3395
                     /gene="ag43"
                     /locus_tag="RHX21_004327"
     CDS             276..3395
                     /gene="ag43"
                     /locus_tag="RHX21_004327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin Ag43"
                     /protein_id="HDV1989423.1"
                     /translation="MKRHLNTSYRLVWNHITGTLVVASELARSRGKRAGVAVALSLAA
                     VTSVPALAADTVVQAGETVNDGTLTNHDNQIVFGTANGMTISTGLEYGPDNEANTGGQ
                     WIQNGGTANNTTVTGGGLQRVNAGGSVSDTVISAGGGQSLQGQAVNTTLNGGEQWVHE
                     DGIATGTVINEKGWQAIKSGAVATDTVVNTGAEGGPDAENGDTGQTVYGDAVRTTINK
                     NGRQIVAAEGTANTTVVYAGGDQTVHGHALDTTLNGGYQYVHNGGTASGTVVNSDGWQ
                     IVKNGGVAGNTTVNQKGRLQVDAGGTATNVTLKQGGALVTSTAATVTGINRLGAFSVV
                     EGKADNVVLENGGRLDVLTGHTATNTRVDDGGTLDVRNGGTATTVSMGNGGVLLADSG
                     AAVSGTRSDGKAFSIGGGQADALMLEKGSSFTLNAGDTATDTTVNGGLFTARGGTLAG
                     TTTLNNGAILTLSGKTVNNDTLTIREGDALLQGGSLTGNGSVEKSGSGTLTVSNTTLT
                     QKAVNLNEGTLTLNDSTVTTDVIAQRGTALKLTGSTVLNGAIDPTNVTLASGATWNIP
                     DNATVQSVVDDLSHAGQIHFTSTRTGKFVPATLKVKNLNGQNGTISLRVRPDMAQNNA
                     DRLVIDGGRATGKTILNLVNAGNSASGLATSGKGIQVVEAINGATTEEGAFVQGNKLQ
                     AGAFNYSLNRDSDESWYLRSENAYRAEVPLYASMLTQAMDYDRILAGSRSHQTGVSGE
                     NNSVRLSIQGGHLGHDNNGGIARGATPESSGSYGFVRLEGDLLRTEVAGMSVTAGVYG
                     AAGHSSVDVKDDDGSRAGTVRDDAGSLGGYLNLIHNASGLWADIVAQGTRHSMKASSD
                     NNDFRARGWGWLGSLETGLPFSITDNLMLEPQLQYTWQGLSLDDGQDNAGYVKFGHGS
                     AQHVRAGFRLGSHNDMTFGKGTSSRDTLRGSAKHSVRELPVNWWVQPSVIRTFSSRGD
                     MSMGTAAAGSNMTFSPSQNGTSLDLQAGLEARVRENITLGVQAGYVHSVSGSSAEGYN
                     GQATLNVTF"
     gene            3516..6032
                     /locus_tag="RHX21_004328"
     CDS             3516..6032
                     /locus_tag="RHX21_004328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708766.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989424.1"
                     /translation="MLQIVGALILLIAGFAILRLLFRALISTASALAGLILLCLFGPA
                     LLAGYITERITRLFHIRWLAGVFLTIAGMIISFMWGLDGKHIALEAHTFDSVKFILTT
                     ALAGGLLAVPLQIKNIQQNGITPEDISKEINGYYCCFYTAFFLMACSACAPLIALQYD
                     ISPSLMWWGGLLYWLAALVTLLWAASQIQALKKLTCAISQTLEEQPVLNSKSWLTSLQ
                     NDYSLPDSLTERIWLTLISQRISRGELREFELADGNWLLNNAWYERNMAGFNEQLKEN
                     LSFTPDELKTLFRNRLNLSPEANDDFLDRCLDGGDWYPFSEGRRFVSFHHVDELRICA
                     SCGLTEVHHAPENHKPDPEWYCSSLCRETETLCQEIYERPYNSFISDATANGLILMKL
                     PETWSTNEKMFASGGQGHGFAAERGNHIVDRVRLKNARILGDNNARNGADRLVSGTEI
                     QTKYCSTAARSVGAAFDGQNGQYRYMGNNGPMQLEVPRDQYAGAVETMRNKIREGKVP
                     GVTDPAEASRLIRRGHLTYTQARNITRFGTIESVTYDIAEGSVVSLAAGGISFALTAS
                     VFWLSTGDRDAALQTAAVQAGKTFTRTLAVYVTTQQLHRLSVVQGMLKHIDFSTASPT
                     VRLALQKGTGAGNISALNKVMKGTLVTSLALVAVTTGPDMIKMLRGRISGTQFIRNLA
                     VASSGVAGGAVGSVAGGILFSPLGPFGALTGRVVGGVLGGMIASAVSGKIAGALVEED
                     RVKILAMIHEQVTWLAGSFLLTGHEIENLNENLARVIDQNALEIIFAAGIQQRAATNM
                     LIKPLVVSIIRQRPVMEYDASHLGNMVNRLEEALPPELPA"
     gene            6108..6563
                     /locus_tag="RHX21_004329"
     CDS             6108..6563
                     /locus_tag="RHX21_004329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989425.1"
                     /translation="MIHLFKTCMITAFILGLTWSAPLRAQDQRYISIRNTDTIWLPGN
                     ICAYQFRLDNGGNDEGFGPLTITLQLKDKYGQTLVTRKMETEAFGDSNATRTTDAFLE
                     TECVENVATTEIIKATEESNGHRVSLPLSVFNPQDYHPLLITVSGKNVN"
     gene            6642..6875
                     /locus_tag="RHX21_004330"
     CDS             6642..6875
                     /locus_tag="RHX21_004330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001119724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF905 family protein"
                     /protein_id="HDV1989426.1"
                     /translation="MPGYTEYVLAEGSFSYGQAVAVITAYRNVFIQDDPGMHFRRVIR
                     NAEGQRRWRCRNSEPDAGKVLNTRLASDGLLRQ"
     gene            6975..7793
                     /locus_tag="RHX21_004331"
     CDS             6975..7793
                     /locus_tag="RHX21_004331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HDV1989427.1"
                     /translation="MRLASRFGYANQIRRDRPLTHEELMHYVPGIFGEDKHTSRSQNY
                     TYIPTITVLESLQREGFQPFFACQTRVRDPGRRGYTKHMLRLRRAGEINGEHVPEIIL
                     LNSHDGTSSYQMLPGYFRFVCQNGCVCGQSLGEVRVPHRGNVVDRVIEGAYEVVGVFD
                     RIEEKRDAMQSLILPPPARQALAQAALTYRYGDEHQPVTTADILTPRRREDYGKDLWS
                     AYQTIQENMLKGGISGRSAKGKRIHTRAIHSIDTDIKLNRALWVMAETLLESLR"
     gene            7848..>8219
                     /locus_tag="RHX21_004332"
     CDS             7848..>8219
                     /locus_tag="RHX21_004332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HDV1989428.1"
                     /translation="MKTISHNSTTSSVSVTAASGNDQPQLVATIVPDEQRISFWPQHF
                     GLIPQWVTLEPRIFGWMDRLCEDYCGGIWNLYTLNNGGAFMAPEPDDNDDETWVLFNA
                     MNGNRAEMSPEAAGIAACLMTY"
BASE COUNT         1985 a         2159 c         2301 g         1774 t
ORIGIN      
        1 cctgccgtta atagaataaa acgatcgata aaacaggtat cgatcgttac tatcgatcgt
       61 ttatagtggt taatggtctg cgaaaaggca gctgaatctc ttcatcatgc agaacggaat
      121 tgcacacaac ggactgatgc ttctctggcg gatgagagag gggaaacatt tatgtccggg
      181 aaaaaccact ttatctgacc atgctgtttt gtacctgccg gtacccacat ctgtgggtac
      241 cggctttttt attcaccctc tgtaaggaaa agctgatgaa acgacatctg aacaccagct
      301 acaggctggt atggaatcac attacgggca ccctggtggt ggcctccgaa ctggcccgct
      361 cacggggaaa acgcgccggt gtggcggttg cgctgtctct tgctgctgtc acatcagtcc
      421 cggcactggc tgctgacacg gttgtacagg cgggagaaac cgtgaacgac ggaacactga
      481 caaatcatga caaccagatt gtcttcggta cggccaacgg aatgaccatc agtaccgggc
      541 tggagtatgg gccggataac gaggccaata ccggcggcca atggatacaa aatggcggta
      601 ccgccaacaa cactactgtc accggtggtg gtcttcagag agtgaatgcc ggaggaagcg
      661 tttcagacac ggttatcagt gccggaggcg gacagagcct tcaggggcag gcagtgaaca
      721 ccactctgaa cggcggtgag cagtgggtac atgaagacgg gattgcaacg ggtaccgtca
      781 ttaatgagaa gggctggcag gccatcaaat ccggcgcagt ggcaaccgac acggttgtga
      841 ataccggcgc ggaaggggga ccggatgcgg aaaatggtga taccgggcag accgtctacg
      901 gagatgccgt acgcaccacc atcaataaaa atggtcgtca gattgtggct gctgaaggaa
      961 cggcaaatac cactgtggtt tatgccggcg gcgaccagac tgtacatggt cacgcactgg
     1021 ataccacgct gaatgggggg taccagtatg tgcacaacgg cggtacggcg tctggcactg
     1081 ttgtaaacag tgacggctgg cagattgtca aaaacggggg tgtggccggg aataccaccg
     1141 ttaatcagaa gggcagactg caggtggacg ccggtggtac agccacgaat gtcaccctga
     1201 agcagggcgg cgcactggtt accagtacgg ctgcaaccgt taccggcata aaccgcctgg
     1261 gagcattctc tgttgtggag ggtaaagctg ataatgtcgt actggaaaat ggcggacgcc
     1321 tggatgtgct gaccggacac acagccacta atacccgcgt ggatgatggc ggaacgctgg
     1381 atgtccgcaa cggtggcacc gccaccaccg tatccatggg aaatggcggt gtactgctgg
     1441 ccgattccgg tgccgctgtc agtggtaccc ggagcgacgg aaaggcattc agtatcggag
     1501 gcggtcaggc ggatgccctg atgctggaaa aaggcagttc attcacgctg aacgccggtg
     1561 atacggccac ggataccacg gtaaatggcg gactgttcac cgccaggggc ggcacactgg
     1621 cgggcaccac cacgctgaat aacggcgcca tacttaccct ttccgggaag acggtgaaca
     1681 acgataccct gaccatccgt gaaggcgatg cactcctgca gggaggctct ctcaccggta
     1741 acggcagcgt ggaaaaatca ggaagtggca cactcactgt cagcaacacc acactcaccc
     1801 agaaagccgt caacctgaat gaaggcacgc tgacgctgaa cgacagtacc gtcaccacgg
     1861 atgtcattgc tcagcgcggt acagccctga agctgaccgg cagcactgtg ctgaacggtg
     1921 ccattgaccc cacgaatgtc actctcgcct ctggtgccac ctggaatatt cccgataacg
     1981 ccacggtgca gtcggtggtg gatgacctca gccatgccgg acagattcat ttcacctcca
     2041 cccgcacagg gaagttcgta ccggcaaccc tgaaagtgaa aaacctgaac ggacagaatg
     2101 gcaccatcag cctgcgtgta cgcccggata tggcacagaa caatgctgac agactggtca
     2161 ttgacggtgg cagggcaacc ggaaaaacca tcctgaacct ggtgaacgcc ggcaacagtg
     2221 cgtcggggct ggcgaccagc ggtaagggta ttcaggtggt ggaagccatt aacggtgcca
     2281 ccacggagga aggggccttt gtccagggga ataagctgca ggccggtgcc tttaactact
     2341 ccctcaaccg ggacagtgat gagagctggt atctgcgcag tgaaaatgct tatcgtgcag
     2401 aagtccccct gtatgcctcc atgctgacac aggcaatgga ctatgaccgg attctggcag
     2461 gctcccgcag ccatcagacc ggtgtaagcg gtgaaaataa cagcgtccgt ctcagcattc
     2521 agggcggtca tctcggtcac gataacaacg gcggtattgc ccgtggagcc acgccggaaa
     2581 gcagcggcag ctatggcttc gtccgtctgg agggtgacct gctcagaaca gaggttgccg
     2641 gtatgtctgt gaccgcgggg gtatatggtg ctgctggcca ttcttccgtt gatgttaagg
     2701 atgatgacgg ctcccgtgcc ggcacggtcc gggatgatgc cggcagcctg ggcggatacc
     2761 tgaatctgat acacaacgcc tccggcctgt gggctgacat tgtggcccag ggaacccgcc
     2821 acagcatgaa agcctcatcg gacaataacg acttccgcgc ccggggctgg ggctggctgg
     2881 gttcgctgga aaccggtctg cccttcagta tcactgacaa tctgatgctg gagccgcaac
     2941 tgcagtacac ctggcaggga ctctccctgg atgacggcca ggataacgcc ggttatgtga
     3001 agttcgggca tggcagtgca caacatgtgc gtgccggctt ccgtctgggc agccacaacg
     3061 atatgacctt tggtaaaggc acctcatccc gtgacaccct gcgcggcagt gccaaacaca
     3121 gtgtgcgtga actgccggtg aactggtggg tacagccttc tgttatccgc accttcagct
     3181 cccgggggga catgagcatg ggtacagccg cagccggcag taacatgacg ttctcaccgt
     3241 cacagaatgg tacgtcactg gacctgcagg ccggactgga agcccgtgtc cgggaaaata
     3301 tcaccctggg cgttcaggca ggttatgtcc acagcgtcag cggcagcagc gctgaaggct
     3361 ataacggtca ggccacgctg aatgtgacct tctgacagaa ccatcgcctc tctgtggtcc
     3421 cggtcatcat gatcgggacc cggaccggcg caacggatat tcaacgccac attcgctggc
     3481 attaacaata acatgatatt catcacggag tgactatgtt acagatagtc ggcgcgctga
     3541 tcctgctgat cgcaggattt gccattcttc gccttttgtt cagagcatta atcagcacgg
     3601 cttctgcgct ggcagggctc atattgctgt gtctgttcgg cccggcctta ctggctggct
     3661 atatcaccga acgcataacc cggttgttcc atattcgctg gctggcaggc gtatttctga
     3721 cgattgccgg aatgatcatc agcttcatgt ggggacttga tggtaaacat atcgcgctgg
     3781 aggctcacac ctttgactct gtgaaattta ttctgaccac cgctctcgcc ggtggtctgc
     3841 tggctgttcc cctgcagatc aaaaacattc agcagaacgg gatcacacca gaagatatca
     3901 gcaaggaaat taacgggtat tactgctgtt tttatactgc ctttttcctt atggcgtgtt
     3961 ctgcatgcgc accattgatc gcgttacagt acgatatttc accgtcactg atgtggtggg
     4021 gcgggttgtt gtactggctg gctgcattag tgacgctgct atgggcggcc agccaaatcc
     4081 aggcgctgaa aaaactgacc tgtgccatca gccagacact ggaagaacaa ccggtgctca
     4141 acagtaaatc gtggctgacc agtttgcaaa acgattacag ccttcctgac tcactgacgg
     4201 agcgcatctg gctgacgctc atttctcaac ggatttcccg gggagagctg agggaatttg
     4261 aactggcaga cggaaactgg ttactgaaca atgcctggta tgaaagaaac atggcagggt
     4321 ttaacgaaca gttgaaagag aacctgtcat tcacacctga tgaactgaaa acgctcttcc
     4381 ggaaccgcct gaatttatca ccggaagcga atgacgattt tctcgatcgt tgcctggacg
     4441 gcggtgactg gtatcccttt tcagaaggtc gccgttttgt atcattccat cacgtggatg
     4501 agcttcgtat ctgtgcctcc tgcgggctga cagaagtaca tcatgccccg gaaaatcata
     4561 agccggatcc ggaatggtac tgctcctctc tttgtcgcga aacagaaaca ctgtgtcagg
     4621 aaatttatga acgcccttac aacagcttta tttccgatgc aacggcgaat ggtctgattc
     4681 tcatgaaact gccggaaacc tggagtacaa atgagaaaat gtttgcttcc ggagggcagg
     4741 gacatgggtt tgccgctgaa cggggaaacc atattgtcga cagagtccgt ctgaaaaacg
     4801 cacggatcct cggtgataat aatgccagaa atggagcaga cagactggtc agcggaacag
     4861 aaatccagac gaaatattgt tcaactgcag cccgtagcgt cggtgcggca ttcgacggac
     4921 aaaacggaca gtatcgttac atgggaaata atggccccat gcaactggaa gtcccccgtg
     4981 atcagtatgc cggcgctgtt gaaaccatga ggaataagat ccgcgaaggt aaagtacccg
     5041 gtgtaaccga tcccgcagaa gcatcccggc tgattcgtcg gggacatctg acttatactc
     5101 aggcccgtaa tatcacccgg ttcgggacca tcgaatcggt cacttatgat attgccgagg
     5161 gttcggttgt cagtctggcg gccggaggga tcagttttgc cctgacggca tcggtcttct
     5221 ggctcagcac cggcgatcgc gatgctgccc tgcagacagc tgctgtccag gcaggaaaaa
     5281 ccttcacccg cacactggct gtctacgtca caacccagca actccaccgg ctcagtgttg
     5341 ttcagggtat gctgaagcac attgattttt cgactgccag cccgactgtc cgactggctc
     5401 ttcagaaggg gaccggtgca ggaaatatca gtgccctgaa caaagtgatg aagggtacgc
     5461 tggtgacatc tctggcactg gtagctgtca caaccggccc tgacatgatc aaaatgttgc
     5521 ggggacggat ctccggtacg cagttcatca ggaatcttgc cgtggcatct tccggtgtgg
     5581 caggtggtgc tgtcgggtca gtggcgggcg gaatactgtt cagtccactg ggaccatttg
     5641 gtgcactgac agggcgtgtg gttggcggtg ttctgggggg aatgattgcc tccgctgtat
     5701 caggaaaaat tgccggagcg ctggttgaag aagatcgcgt caaaattctg gcaatgattc
     5761 atgagcaggt gacatggctt gccggcagtt tcctgctgac cggacatgag attgaaaatc
     5821 tgaacgagaa tctggcccgt gttatcgatc agaatgctct ggagatcatt ttcgccgccg
     5881 gtatacaaca acgggccgcg accaatatgt taatcaaacc actggtggtc agtatcatca
     5941 ggcaacgccc cgtcatggaa tatgatgcat cccatctcgg caatatggtt aaccgactgg
     6001 aagaagcatt acccccggag ttaccggcat aacggctatt ctgcgccttt tacgctttat
     6061 cacctgattt gtcagtgtca tcgtcatgac tcagagaggt aaataccatg attcacctgt
     6121 tcaaaacctg catgattacc gccttcattc tggggttaac gtggtctgcc ccactccggg
     6181 cacaggatca acgttacatc agtatacgca atacagatac gatatggctc ccgggaaata
     6241 tttgtgctta ccagttccgg ctggataatg gcggaaacga tgaaggattt ggccccctca
     6301 ccatcactct gcaactcaaa gacaaatatg gtcagacgct ggtgaccaga aaaatggaaa
     6361 cggaagcttt tggtgacagt aatgccacgc gaaccacaga cgcatttctg gaaacggagt
     6421 gcgtggaaaa tgtcgccaca accgaaatca ttaaagcaac tgaagaaagt aacggccatc
     6481 gtgtcagtct gccgttatcg gttttcaatc cccaggacta ccatccactg ctgattaccg
     6541 tttccggaaa aaacgttaac tgatccctga agtcagtttc atgcttcagc ctctgtcaca
     6601 acgcgtggca gaggcttttt atttatcagg agaaaacaga tatgccgggt tacacagagt
     6661 atgtcctggc tgaaggatct ttctcatacg ggcaggcggt tgctgtcata acagcttacc
     6721 gcaatgtgtt tatccaggat gacccgggaa tgcatttccg tcgggttatc cgcaacgcgg
     6781 aaggtcagcg acgctggcgc tgccggaatt ctgaacccga tgccggaaag gtgcttaata
     6841 cgcggctcgc cagtgacggt cttctcagac aataaacgtc attcatttca cccatcaggc
     6901 cgcgtcttct ccgggagacg tggctttttc atttattaca ccagtaaatc ttaaccaccg
     6961 ataaggagca aattatgcga ctagccagtc gttttggtta tgcgaaccag atacgccgtg
     7021 accgtccgct gacacacgaa gaactgatgc actatgtgcc ggggattttc ggggaagata
     7081 aacacacgtc ccgaagccag aactatacgt acatccccac catcaccgta ctggaaagcc
     7141 tgcagcggga aggctttcag ccattcttcg cctgccagac ccgtgtgcgc gacccgggcc
     7201 gccggggata cacaaaacac atgctacgtc tgcggcgggc cggagagata aacggagaac
     7261 atgtccctga aattattctg ctcaactctc atgacggtac ctccagctac cagatgctgc
     7321 cgggttactt caggttcgtc tgccagaacg gatgcgtctg tggtcagtct ctgggggaag
     7381 tgcgtgttcc gcaccgggga aatgtggtgg acagagtcat tgaaggggct tacgaggtgg
     7441 tgggggtttt tgaccggatt gaggaaaagc gtgatgccat gcagtcgctg attctgccgc
     7501 caccggcacg ccaggcgctg gcacaggcgg cactgactta ccgttatggt gacgaacatc
     7561 agcccgtcac caccgccgac attctgacgc cacgacgccg ggaggattac ggtaaggacc
     7621 tgtggagtgc ttatcagacc attcaggaga atatgctgaa aggcggaatt tcaggtcgca
     7681 gcgctaaagg aaaacgtatc catacccgtg ccattcacag cattgacact gacattaagc
     7741 tcaaccgcgc attgtgggtg atggcggaaa cgctgctgga gagcctgcgc tgattcagcc
     7801 attaccctga aaaccacgca tttatttgtc ctttaaggag tcatttcatg aaaaccattt
     7861 cacataattc caccacatct tctgtttccg taaccgctgc atcagggaat gaccagcctc
     7921 agctggttgc caccatagtc cctgatgaac agcgcatcag cttctggccg cagcactttg
     7981 gcctcattcc acagtgggtg accctggagc cccgtatctt cggctggatg gaccgtctgt
     8041 gtgaagacta ctgcggtggt atctggaatc tgtacaccct gaacaacggc ggggcattta
     8101 tggcacccga accggatgac aatgatgacg aaacatgggt actgttcaat gccatgaacg
     8161 gtaaccgcgc tgaaatgagc ccggaagctg ccggcattgc tgcctgtctg atgacgtac
//
LOCUS       DAPGUL010000171         8190 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.174, whole genome shotgun sequence.
ACCESSION   DAPGUL010000171 DAPGUL010000000
VERSION     DAPGUL010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8190
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.174"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..512
                     /locus_tag="RHX21_004333"
     CDS             <1..512
                     /locus_tag="RHX21_004333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000056329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989429.1"
                     /translation="DSTKKFMLKEIEFDKENNSFYLSNFLTAQGKTVWPSLLEEASQH
                     DDAWLEQEILNRGLLATHYPRRKPNSTEIIQAKVPHTAARTLAEGEFNRLFARGLSSR
                     AIAEGIEFVEAYRARHSENPRPESQAVIGKKFRPEEILEDLRNNPGVDTALGVPPGPN
                     SGITIKLVK"
     gene            1056..1274
                     /locus_tag="RHX21_004334"
     CDS             1056..1274
                     /locus_tag="RHX21_004334"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989430.1"
                     /translation="MDVKADIIAWLLKQQDWFQELAERLIQQDDLTDNDLQQVIALLK
                     PPPMDEQKRHTILSQAWHLQSRDLEHSG"
     gene            1673..2695
                     /gene="istA"
                     /locus_tag="RHX21_004335"
     CDS             1673..2695
                     /gene="istA"
                     /locus_tag="RHX21_004335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element IS100 family transposase"
                     /protein_id="HDV1989431.1"
                     /translation="MVTFETVMEIKILHKQGMSSRAIARELGISRNTVKRYLQAKSEP
                     PKYTPRPAVASLLDEYRDYIRQRIADAHPYKIPATVIAREIRDQGYRGGMTILRAFIR
                     SLSVPQEQEPAVRFETEPGRQMQVDWGTMRNGRSPLHVFVAVLGYSRMLYIEFTDNMR
                     YDTLEACHRNAFRFFGGVPREVLYDNMKTVVLQRDAYQTGQHRFHPSLWQFGKEMGFS
                     PRLCRPFRAQTKGKVERMVQYTRNSFYIPLMTRLRPMGITVDVETANRQGLRWLHDVA
                     NQRKHETIQARPCDRWLEEQQSMLALPPEKKEYDVHLDENLVNFDKHPLHHPLSIYDS
                     FCRGVA"
     gene            2695..3474
                     /gene="istB"
                     /locus_tag="RHX21_004336"
     CDS             2695..3474
                     /gene="istB"
                     /locus_tag="RHX21_004336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016243248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element IS100kyp family helper ATPase
                     IstB"
                     /protein_id="HDV1989432.1"
                     /translation="MMELQHQRLMALAGQLQLESLISAAPALSQQAVDQEWSYMDFLE
                     HLLHEEKLARHQRKQAMYTRMAAFPAVKTFEEYDFTFATGAPQKQLQSLRSLSFIERN
                     ENIVLLGPSGVGKTHLAIAMGYEAVRAGIKVRFTTAADLLLQLSTAQRQGRYKTTLQR
                     GVMAPRLLIIDEIGYLPFSQEEAKLFFQVIAKRYEKSAMILTSNLPFGQWDQTFAGDA
                     ALTSAMLDRILHHSHVVQIKGESYRLRQKRKAGVIAEANPE"
     gene            3766..4557
                     /locus_tag="RHX21_004337"
     CDS             3766..4557
                     /locus_tag="RHX21_004337"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989433.1"
                     /translation="MMTNWSEADEQALSALNERLNVKDPAENARNKLAVQTSVNQIIT
                     QLEQTAKAFSQSNIDCLRALRADAISKRRIALDSERIKDDSLEGIGSPVWRAMWEAAR
                     DYSRTPYPDKAFSATDEARCVLCNQALSAEAQQRLNNLEAFVQSRLESDAATTECLYV
                     QAIGSITIPPSMAEIATLCASAAIQEEWNKYLTGIWSAASLSRQALTEHEATQTAVPL
                     ADLTEAITNLRTYRDRLQGEADQFQRDAAGFDRAKALQNKNEAEA"
     gene            4680..5579
                     /locus_tag="RHX21_004338"
     CDS             4680..5579
                     /locus_tag="RHX21_004338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001367706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDV1989434.1"
                     /translation="MTQKVVTEAYAARFNRELKVLGAPSLQVELVKIRTENAKVLHQL
                     QLKGAQRDKLHNVLSEGERRIISLAAFLADVTDRPGSAPFIFDDPISSLDHEFEWQVA
                     KRLVELAKSRQVIILTHRLSLYGVIEDLARKEGDPWKKQHHKSICIESFDGAAGHPAD
                     QEVWNANTKSANNILLTRLDSAYKSGQEHGAIAFRGLAQGVCSDFRKLIERSVEEDSF
                     NGVVIRHRRGIQTDGRLPYVQDITAEDCKLIESLMTKYSCYEHSQSTEMPASIPEYKE
                     LRADISTLKEWRDQIKTRRTLMK"
     gene            complement(6130..6861)
                     /locus_tag="RHX21_004339"
     CDS             complement(6130..6861)
                     /locus_tag="RHX21_004339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus Gp2 family protein"
                     /protein_id="HDV1989435.1"
                     /translation="MNQPIHNAYWLSRFESILNSALAQHRAISLIRVDLRFPEYMPAT
                     IMDPDPDSAVISRFSESLKAKIQAYQRHQRRAGKRVHATTLHYFWCREFGKKYGRKHY
                     HVILLLNKDTWCSPGDFTVPSSLATLIQLAWCSALHLEPWLGNGLVHFARWTPSRKPA
                     SADAPPSSDDTPLPGGCSDTRKASDKKSGGSAVLWVTRGDEEAVQKALERARYLVKNE
                     TKLHDGSGQRNYGCSRGSGRLLDGR"
BASE COUNT         2391 a         1901 c         1900 g         1998 t
ORIGIN      
        1 atgattcaac caaaaaattt atgcttaaag aaattgaatt tgataaagaa aataacagtt
       61 tttatttaag caattttctt actgctcaag gtaagactgt gtggccttct ttgttagaag
      121 aagcatctca acatgatgat gcatggcttg agcaagaaat cctaaataga ggattactgg
      181 ccacccatta tcctagaaga aagcctaata gcactgagat aattcaggct aaagttcctc
      241 acacagctgc tcgaacttta gctgaaggag aattcaatcg tttatttgcc cgaggcttga
      301 gctcgcgagc aatagcagaa ggaattgaat ttgttgaagc ttaccgagca agacactcag
      361 aaaatccacg ccctgaatct caagctgtta tcgggaaaaa gttccgaccg gaagaaattc
      421 ttgaggattt acgtaataac ccaggtgtag atacagcatt aggcgttcct cctggcccta
      481 actcaggcat aacaattaaa cttgttaagt aaaaaattaa taagaggcac tttcggaatt
      541 taaatcccta agtgccttta tgatgacctg ttcccccatt gttcaacaca cactgatcta
      601 agaaagcttg gttgcagaca ggccatgaat aacacggtta ctgtgagcga gcagcggacg
      661 gcttaggttt tatgatactg atcaaggcta atatcatggc gatgaaatca ttcggataat
      721 tttaatctca cctttatata tcactgccca gtcgccaaaa gttaggatac ttatgcctcg
      781 tctgcaaacc tgtagcgaag tacccgcaga cgttcacttc ccggactttt caggtagtga
      841 gcagacttca tttcgggatc tactggagcg tgagcatttt actgtggatt acgaatacac
      901 tattgccaat ttttgttgat caagtgttgc tcatctcaag tggctgatgc actatcagat
      961 gattcttaac gccacacact agggcgtggt agcaatgtgc tgggaggcac attcagtttc
     1021 gcttccttta tcgtcatgaa tgaaggaggg cagtaatgga tgtaaaggcc gatatcatag
     1081 cctggctgtt aaagcagcag gactggtttc aggaactagc ggaaagactc attcaacagg
     1141 atgacctgac agataatgac cttcagcagg ttattgcttt gctcaagccc ccccccatgg
     1201 acgaacaaaa acgacacacc atactttccc aggcctggca tctgcagagc agggatctgg
     1261 aacactcagg ttaagtcgga tcgaagctgt aaagggtatt gagaaccttg ctccacgttt
     1321 accgctcgat ttcggttcag ggaatctgac tgttatttac ggccataacg ggtccggtaa
     1381 atccagctat acgcgtgtgc tcaaacgtat gtccggaaaa cctagagcag ctcagcttaa
     1441 atctaatgtc tttaatccct taccacctga gcgaagttgc cacattaaat ggaaagcgaa
     1501 tgaaagcaat gctgaagcgg actggtcagc tgacagccct ccgatcgatg ccctgaaagg
     1561 cattgatatc ttcgatacgg atgaagtgtc acgaacggtg caatagtgat ccacacccaa
     1621 cgcctgaaat cagatccagg gggtaatctg ctctcctgat tcaggagagt ttatggtcac
     1681 ttttgagaca gttatggaaa ttaaaatcct gcacaagcag ggaatgagta gccgggcgat
     1741 tgccagagaa ctggggatct cccgcaatac cgttaaacgt tatttgcagg caaaatctga
     1801 gccgccaaaa tatacgccgc gacctgctgt tgcttcactc ctggatgaat accgggatta
     1861 tattcgtcaa cgcatcgccg atgctcatcc ttacaaaatc ccggcaacgg taatcgctcg
     1921 cgagatcaga gaccagggat atcgtggcgg aatgaccatt ctcagggcat tcattcgttc
     1981 tctctcggtt cctcaggagc aggagcctgc cgttcggttc gaaactgaac ccggacgaca
     2041 gatgcaggtt gactggggca ctatgcgtaa tggtcgctca ccgcttcacg tgttcgttgc
     2101 tgttctcgga tacagccgaa tgctgtacat cgaattcact gacaatatgc gttatgacac
     2161 gctggaggcc tgccatcgta atgcgttccg cttctttggt ggtgtgccgc gcgaagtgtt
     2221 gtatgacaat atgaaaactg tggttctgca acgtgacgca tatcagaccg gtcagcaccg
     2281 gttccatcct tcgctgtggc agttcggcaa ggagatgggc ttctctcccc gactgtgtcg
     2341 ccccttcagg gcacagacta aaggtaaggt agaacggatg gtgcagtaca cccgtaacag
     2401 tttttacatc ccactaatga ctcgcctgcg cccgatgggg atcactgtcg atgttgaaac
     2461 agccaaccgc caaggtctgc gctggctgca cgatgtcgct aaccaacgaa agcatgaaac
     2521 aatccaggca cgtccctgcg atcgctggct cgaagagcag cagtccatgc tggcactgcc
     2581 tccggagaaa aaagagtatg atgtgcatct tgatgaaaat ctggtgaact tcgacaaaca
     2641 ccccctgcat catccactct ccatctacga ctcattctgc agaggagtgg cgtgatgatg
     2701 gaactgcaac atcaacgact gatggcgctc gccgggcagt tgcaactgga aagccttata
     2761 agcgcagcgc ctgcgctgtc acaacaggca gtagaccagg aatggagtta tatggacttc
     2821 ctggagcatc tgcttcatga agaaaaactg gcacgtcatc aacgtaaaca ggcgatgtat
     2881 acccgaatgg cagccttccc ggcggtgaaa acgttcgaag agtatgactt cacattcgcc
     2941 accggagcac cgcagaagca actccagtcg ttacgctcac tcagcttcat agaacgtaat
     3001 gaaaatatcg tattactggg gccatcaggt gtggggaaaa cccatctggc aatagcgatg
     3061 ggctatgaag cagtccgtgc aggtatcaaa gttcgcttca caacagcagc agatctgtta
     3121 cttcagttat ctacggcaca acgtcagggc cgttataaaa cgacgcttca gcgtggagta
     3181 atggcccccc gcctgctcat cattgatgaa ataggctatc tgccgttcag tcaggaagaa
     3241 gcaaagctgt tcttccaggt catcgctaaa cgttacgaaa agagcgcaat gatcctgaca
     3301 tccaatctgc cgttcgggca gtgggatcaa acgttcgccg gtgatgcagc actgacctca
     3361 gcgatgctgg accgtatctt acaccactca catgtcgttc aaatcaaagg agaaagctat
     3421 cgactcagac agaaacgaaa ggccggggtt atagcagaag ctaatcctga gtaaaacggt
     3481 ggatcaatat tgggccgttg gtggagatat aagtggatca cttttcatcc gtcgttgaca
     3541 tgaagctctg cattatctca cccaagagag tgccactacc tatataccga gtgtggtggg
     3601 gctttttgaa aaactggccc agtacctgaa actggtacgc gataagctaa gggatgaaca
     3661 gtctcagcta gtcagcaaac ttcccgaact acctgctgtt tatcagcgtt gtcatattgc
     3721 cactacctat agtgcactaa gtacagcaac taccgaaaat acgcagtgat gacaaactgg
     3781 tctgaggcgg atgagcaagc gcttagtgcc ttgaatgaac gtctgaacgt taaagatccg
     3841 gctgagaacg cccgcaacaa gcttgcggtt caaacatctg ttaatcagat catcactcaa
     3901 cttgagcaga cggcaaaggc ttttagccag tcaaatatcg actgtcttcg ggcgttacgt
     3961 gctgatgcta tcagcaagcg cagaattgcg cttgatagtg aacgaataaa agatgactca
     4021 ctggagggca ttggctcacc tgtatggcgt gccatgtggg aagctgctcg cgactattca
     4081 aggacgccct atccagacaa ggctttttcg gcaacagatg aggcccgttg tgttttatgc
     4141 aatcaggctc tatccgcaga agctcagcag cgtctgaaca atcttgaggc tttcgtgcaa
     4201 tcacgtcttg agagcgatgc tgccacaact gagtgtctgt atgttcaggc aatcggctcg
     4261 ataactattc ctccctcaat ggccgaaatt gctacccttt gtgcaagcgc tgcgattcag
     4321 gaagaatgga ataaatacct aacgggaata tggagtgccg catccctcag tcgtcaggcg
     4381 ctcaccgagc atgaagctac ccagacagca gttcctttgg ctgatttgac cgaagctatc
     4441 acgaatttac gtacttaccg cgaccggctt cagggagaag ccgaccagtt tcagagagat
     4501 gcagcaggat ttgacagggc caaagctttg cagaataaaa acgaagccga agcttgacgg
     4561 tggttatctg gtcaagccga ggctatcaga gccgaagttg aacgcttaaa aaaagaagtg
     4621 aatttgatga atggatatca cttgccgctt cccgtgcatt atcaactcaa tctgctgata
     4681 ttactcagaa agttgtcact gaagcctatg ccgccagatt caaccgtgag ctgaaagttc
     4741 ttggtgctcc tagcttgcag gttgagcttg tgaaaataag gacagaaaat gcgaaagttt
     4801 tgcatcagct acagctaaaa ggagcgcaac gggacaagtt gcacaatgtt ctgagtgaag
     4861 gagaacgtag gattatctca ctggctgcat ttttagccga tgtcactgat cggccgggat
     4921 ctgctccctt catttttgat gaccctattt catctctgga ccacgaattt gagtggcaag
     4981 ttgctaaacg cctcgttgaa ctcgctaaat cgcgtcaggt gattatttta acgcacagac
     5041 tttcccttta cggggtaatt gaagatttgg caagaaaaga gggagaccca tggaaaaagc
     5101 agcaccataa atcgatatgt attgaatcat ttgatggagc tgccggtcat cctgccgatc
     5161 aggaggtctg gaacgcgaat accaaatcag cgaataacat tctcctgact aggctggatt
     5221 cagcctacaa atctggacaa gaacatggcg caatagcttt ccgtgggcta gctcagggcg
     5281 tttgcagtga ttttcgtaaa ctcattgagc gctctgtcga ggaggattca tttaacgggg
     5341 tagttatacg tcatagaaga ggaatccaga ctgacggaag gcttccgtat gtacaggata
     5401 taactgcaga agactgtaaa ttgattgaaa gcctcatgac taaatacagc tgttatgagc
     5461 acagccagtc gacggaaatg cctgcttcta taccagagta taaggagctg cgagcggata
     5521 taagcacgtt aaaagaatgg cgtgatcaga tcaaaacaag gcgcactctt atgaaataac
     5581 ccctcattga atccagtatc tttattgtct tagtaaaaat ctggggtcag tagaaagtat
     5641 catttccgtg ctggatggag aatctcatcg gtaaatccgg atggtatgct tgaagaggcc
     5701 tttctgccag cagttacttg gctagctaag ccataccaga ttgggcggca ttgcggtagc
     5761 tggaagataa tatcagtgaa taccggggga cttaagtacc ttcccggtat cgatgcagag
     5821 cataatagtg ggaacttccg cttctggcac aaagcagact atgagaagag agatgctata
     5881 acatttgagt cccaccaatc gatctgttca tttctatgaa tggcagtaaa tgcaaataac
     5941 cataacaacc aaacgttttt cgacttatgg tcgatgtcgc aaagagtgag gtgtggaaag
     6001 caagcgtgtg aacggaagta gatggctatc cattgcatta cttcaggatg acttttcaga
     6061 aaacgagcta agggcgtcaa ccaacgccct gtagcataag ctcaggtacc ggatgccgtt
     6121 ttacaggctt cacctgccat ccagaagacg ccccgaccca cgactgcaac cataattacg
     6181 ttgacctgaa ccgtcatgca gtttcgtttc atttttcacg agataacggg ctctctccag
     6241 ggctttctgc accgcttcct cgtcaccacg cgtgacccag agcacagcgg atccaccaga
     6301 ctttttgtca gaagccttcc gggtatcaga acacccacca ggcaaaggcg tgtcatcgga
     6361 agaagggggg gcatcagccg atgctggttt acgggaagga gtccacctgg caaaatgaac
     6421 cagtccatta cccagccagg gctcaagatg cagggcgctg caccatgcca gctggatcag
     6481 cgtcgccagc gaagaaggaa cggtgaaatc ccctggcgag caccaggtat ctttgttgag
     6541 cagtaatatc acgtgataat gtttcctgcc atatttcttg ccgaactccc ggcaccagaa
     6601 ataatgcagg gtggttgcat gcacacgctt accggcacgt cgctgatgtc tctggtaagc
     6661 ctggattttg gctttcaggg attcggaaaa acgggagatc accgcagagt ccggatcggg
     6721 atccatgatg gtggcaggca tatactcagg gaaacgtaaa tccacccgga ttaacgagat
     6781 ggcacggtgc tgcgccaggg cactgttgag aatgctttca aaacgggata accagtaagc
     6841 attgtgtatt ggttggttca tgatgagaga tctccgttga tttggattga cttcacatca
     6901 ttaatcaccg tggtaaaact ttactgcatc ccgccattga gcaacaccaa tggctcctga
     6961 ttaaaatgga ataccctaca aacgaaaaga gaatccaact gacacacagg gtaaaaacat
     7021 ctctgcaaaa cataaaataa cagcatgaat ggatttaaaa acgatatgga cgacgagaaa
     7081 agtcagaagg ggaacggatc cacaggacat tcaaacaaaa cgtcacaaac aaaacgtcag
     7141 aaactcaatc agaacgcttt ctggcgctgt gaatcaacaa caatgccaaa acctacagct
     7201 taaccacatt actcaatcac agatgcgaaa tggcacactt aaaacctgtt tacagataat
     7261 cccgccgcaa gaacaaaaaa caccaacatc agaatcgatt ttcttatcct gaaaacgtta
     7321 cttttcacta cgccccataa aacgattaac tatcgataac gtaaaccgca tctgaatcaa
     7381 aacaccagaa ccaatcatca cgctttttct gaaaagagcc ttgcgctaag aaaaaacacc
     7441 agggccagtt aatcatctca tcaatcttat cgttacaaaa acatccagaa agtcgtttaa
     7501 caaaatcatc gtaagcacac agtaaatcac gctaggttat ctcagtcgga tttaagtttt
     7561 tacgtaaaga tacttttctc atgctaacgt cgaaactcga aatctcagga aaggttaaac
     7621 gtaacatcag taaaatcgaa tagcagattg attgcttaaa cagaaaggtt cgttttacaa
     7681 cagcattaaa ctgatttagt taacgtaaag atttactaaa ctggatgtgt atcagatcaa
     7741 acaatgtgtt tagcaatgct taatgaaaac acttgtagaa ttgtttatga aaatacgtgt
     7801 ataacactta ctgaaatgct tagtaaaata cgtgtatata gtatcatacc gacattctca
     7861 acatcttcag acatccatgc agactgagtg ttgatttcag tttttcacgg ccagcatgga
     7921 tctttactgg tcaaaaaaac agacaggttt actctggagt tattttcctg ttcacgtatt
     7981 cagtacagca gaaatcccgt gataacgaga cagtaaacca tcgtaatcag cgtctgtaac
     8041 tccatcgctt taccccagaa aagttaagcc atataatgtg atggatataa gtcgtcgtat
     8101 ccggtaagta cagataacca caacataagc tcattcagta aattttatct ctgaacaaac
     8161 gactatggca tgctcattta tactattcat
//
LOCUS       DAPGUL010000172         7984 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.175, whole genome shotgun sequence.
ACCESSION   DAPGUL010000172 DAPGUL010000000
VERSION     DAPGUL010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7984
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.175"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            43..747
                     /locus_tag="RHX21_004340"
     CDS             43..747
                     /locus_tag="RHX21_004340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="HDV1989436.1"
                     /translation="MNPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDH
                     STIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSRGRTV
                     DFYLSSRRNSKAAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCPSDV
                     EHRQIKYRNNVIECDHGKLKRIINATLGFKSMKTAYATIKGIEVMRALRKGQASAFYY
                     GDPLGEMRLVSRVFEM"
     gene            complement(800..907)
                     /locus_tag="RHX21_004341"
                     /pseudo
     CDS             complement(800..907)
                     /locus_tag="RHX21_004341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904895.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            1033..3918
                     /locus_tag="RHX21_004342"
     CDS             1033..3918
                     /locus_tag="RHX21_004342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HDV1989437.1"
                     /translation="MPRRVTLTDRQKDALLRLPTSQTDLLKHYTLSDEDLGHIRLRRR
                     AHNRFGFALQLCVLRYPGRVLAPGELIPAEVIEFIGAQLGLGADDLVDYAAREETRHE
                     HLAELRGLYGFRTFSGRGASELKEWLFREAEMAVSNEDIARRFVAECRRTRTVLPATS
                     TIERLCAAALVDAERRIETRIASRLPMSIREQLLALLEETADDRVTRFVWLRQFEPGS
                     NSSSANRLLDRLEYLQRIDLPEDLLAGVPAHRVTRLRRQGERYYADGMRDLPEDRRLA
                     ILAVCVSEWQAMLADAVVETHDRIVGRLYRASERICHAKVADEAGVVRDTLKSFAEIG
                     GALVDAQDDGQPLGDVIASGSGWDGLKTLVAMATRLTATMADDPLNHVLDGYHRFRRY
                     APRMLRLLDLRAAPVALPLLEAVTALRTGLNDAAMTSFLRPSSKWHRHLRAQRAGDAR
                     LWEIAVLFHLRDAFRSGDVWLTRSRRYGDLKHALVPAQSIAEGGRLAVPLRPEEWLAD
                     RQARLDMRLRELGRAARAGTIPGGSIENGVLHIEKLEAAAPTGAEDLVLDLYKQIPPT
                     RITDLLLEVDAATGFTEAFTHLRTGAPCADRIGLMNVILAEGINLGLRKMADATNTHT
                     FWELIRIGRWHVEGEAYDRALAMVVEAQAALPMARFWGMGTSASSDGQFFVATEQGEA
                     MNLVNAKYGNTPGLKAYSHVSDQYAPFATQVIPATASEAPYILDGLLMNDAGRHIREQ
                     FTDTGGFTDHVFAACAILGYRFAPRIRDLPSKRLYAFNPSAAPAHLRALIGGKVNQAM
                     IERNWPDILRIAATIAAGTVAPSQILRKLASYPRQNELATALREVGRVERTLFMIDWI
                     LDAELQRRAQIGLNKGEAHHALKRAISFHRRGEIRDRSAEGQHYRIAGMNLLAAIIIF
                     WNTMKLGEVVANQKRDGKLLSPDLLAHVSPLGWEHINLTGEYRWPKP"
     gene            3988..4863
                     /locus_tag="RHX21_004343"
     CDS             3988..4863
                     /locus_tag="RHX21_004343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001201005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA--6-aminopenicillanic acid
                     acyl-transferase"
                     /protein_id="HDV1989438.1"
                     /translation="MRAEVQRHYPHIWQELEGLAQGLEATVDQVFAWNCRGDLVRSTS
                     DGCTTVAGVNAAGERIIAHNEDGFPQLRDECLLATITPSRGLSFTSFAYPGSICGHTF
                     AVNEKGIVNTVNNIRAVYRPQGLPRQILARASLNANTLDEAITILTGQPRSGAFHHTL
                     GQLGDARLFSVEATGQGCSVLPLTTVTGHANHLVHAALAGVEQIVTDSSASRQLRLVQ
                     WRETQPPFDAAAAKTILSDTHDAELPIYRLAADDPDEENTLATAVFTLDANHVRWQIF
                     DINRDDAKFHGEVRG"
     gene            complement(5017..5832)
                     /locus_tag="RHX21_004344"
     CDS             complement(5017..5832)
                     /locus_tag="RHX21_004344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032492145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(3')-Ia"
                     /protein_id="HDV1989439.1"
                     /translation="MSHIQRETSCSRPRLNSNLDADLYGYKWARDNVGQSGATIYRLY
                     GKPDAPELFLKHGKGSVANDVTDEMVRLNWLTAFMPLPTIKHFIRTPDDAWLLTTALP
                     GKTAFQVLEEYPDSGENIVDALAAFLRRLHSIPVSNCPFNSDRVFRLAQAQSRMNNGL
                     VDASDFDDERNGWPVEQVWKEMHKLLPFSPDSVVTHGDFSLDNLIFDEGKLIGCIDVG
                     RVGIADRYQDLAILWNCLGEFSPSLQKRLFQKYGIDNPDMNKLQFHLMLDEFF"
     gene            complement(6168..7004)
                     /locus_tag="RHX21_004345"
     CDS             complement(6168..7004)
                     /locus_tag="RHX21_004345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000480972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /protein_id="HDV1989440.1"
                     /translation="MFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLK
                     PIEDIADELRGADYLVWRNGRGAVRLLGRENNLMLLEYAGERMLSHIVAEHGDYQATE
                     IAAELMAKLYAASEEPLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQMM
                     SNASELRGLHGDLHHENIMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDP
                     RRIAQMADAFSRALDVDPRRLLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQT
                     SY"
     gene            complement(7004..7807)
                     /locus_tag="RHX21_004346"
                     /note="aph(3'')-Ib"
     CDS             complement(7004..7807)
                     /locus_tag="RHX21_004346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(3'')-Ib"
                     /protein_id="HDV1989441.1"
                     /translation="MNRTNIFFGESHSDWLPVRGGESGDFVFRRGDGHAFAKIAPASR
                     RGELAGERDRLIWLKGRGVACPEVINWQEEQEGACLVITAIPGVPAADLSGADLLKAW
                     PSMGQQLGAVHSLSVDQCPFERRLSRMFGRAVDVVSRNAVNPDFLPDEDKSTPQLDLL
                     ARVERELPVRLDQERTDMVVCHGDPCMPNFMVDPKTLQCTGLIDLGRLGTADRYADLA
                     LMIANAEENWAAPDEAERAFAVLFNVLGIEAPDRERLAFYLRLDPLTWG"
BASE COUNT         1795 a         2278 c         2201 g         1710 t
ORIGIN      
        1 tggtgataaa cttatcatcc ccttttgctg atggagctgc acatgaaccc attcaaaggc
       61 cggcattttc agcgtgacat cattctgtgg gccgtacgct ggtactgcaa atacggcatc
      121 agttaccgtg agctgcagga gatgctggct gaacgcggag tgaatgtcga tcactccacg
      181 atttaccgct gggttcagcg ttatgcgcct gaaatggaaa aacggctgcg ctggtactgg
      241 cgtaaccctt ccgatctttg cccgtggcac atggatgaaa cctacgtgaa ggtcaatggc
      301 cgctgggcgt atctgtaccg ggccgtcgac agccggggcc gcactgtcga tttttatctc
      361 tcctcccgtc gtaacagcaa agctgcatac cggtttctgg gtaaaatcct caacaacgtg
      421 aagaagtggc agatcccacg attcatcaac acggataaag cgcccgccta tggtcgcgcg
      481 cttgctctgc tcaaacgcga aggccggtgc ccgtctgacg ttgaacaccg acagattaag
      541 taccggaaca acgtgattga atgcgatcat ggcaaactga aacggataat caacgccacg
      601 ctgggattta aatccatgaa gacggcttac gccaccatca aaggtattga ggtgatgcgt
      661 gcactacgca aaggccaggc ctcagcattt tattatggtg atcccctggg cgaaatgcgc
      721 ctggtaagca gagtttttga aatgtaaggc ctttgaataa gacaaaaggc tgcctcatcg
      781 ctaactttgc aacagtgcca tcatagatat tgtcccgttc gacacctgcg gcgcgcaagg
      841 cgtcgtgctg caggtcgaga gactgcgagc catcggcttt ggagacgcgg gcatatccga
      901 tcagcatgta tcacaaacgt tggtttgagg cggcgcttcg gccacgattg cattgacctc
      961 tggaagtgta tctcaaccag cttcataaac aaagcgtctt gaacgctatc agattttgaa
     1021 aaaggaacat gtatgccgcg tcgcgtcact ctaaccgatc ggcagaaaga cgcgctgttg
     1081 cgcttgccga cttcacagac ggatttgctc aagcactata cgctgagtga tgaagacctt
     1141 gggcatatca ggctgcgtcg gcgcgctcac aacaggttcg gcttcgccct gcaattgtgt
     1201 gtcctgcgct atcccggccg ggtgctggct ccaggcgaac tgatccctgc agaggtcatc
     1261 gaatttatcg gagcgcagct tggcctgggt gccgacgatc tcgtagacta tgctgcccgc
     1321 gaggaaacac ggcacgagca tcttgccgag ttacgggggc tctacggctt ccgcaccttc
     1381 tccggacgtg gtgcgagcga gctgaaggaa tggttgttcc gagaagccga gatggcggtg
     1441 tcgaacgagg atatcgcccg tcgcttcgta gccgagtgcc gacgcacccg cactgtcctt
     1501 cccgcgacat ccacgatcga gcggctttgt gccgcggctc tcgtcgatgc cgagcgacgc
     1561 atcgagacga ggatcgccag tcggctgcct atgtcgatcc gagaacagtt gctggcattg
     1621 ctcgaggaga cggctgatga tcgggtgacc cgttttgtgt ggctgcgcca gttcgagcct
     1681 ggctcgaact cttcgtcggc caaccggctg ctcgaccggc tcgaatatct gcaacgcatc
     1741 gatctccccg aggatctgct tgccggcgtt cctgcccatc gggtgactcg tctgcgcagg
     1801 cagggtgaac ggtattatgc cgacggcatg cgcgatctcc cggaggacag gcggcttgcg
     1861 atcttggctg tttgcgtctc ggaatggcag gcgatgttgg ccgacgcagt ggtcgaaacc
     1921 cacgaccgga tcgtcggccg tctctaccgt gcttcggagc gtatttgcca tgcaaaggtc
     1981 gcagacgaag cgggggtggt gcgtgacacc ctgaaatcct tcgccgagat cgggggcgcc
     2041 ctggtcgatg cacaggatga tggccagccg ctgggcgatg tcatcgcgag tgggtcaggg
     2101 tgggacggct taaaaaccct tgttgcaatg gcaaccaggc tgaccgccac catggccgac
     2161 gatccgctca atcatgtgct cgacggttat caccgcttcc gccgatacgc tccacgcatg
     2221 ttgcgcctgc tcgatctgcg agctgcgccc gttgcactgc cgcttctgga agcggtgacg
     2281 gcccttcgta ccggtttgaa cgatgccgcg atgaccagct tcttgcggcc cagctcgaaa
     2341 tggcatcgcc accttcgggc ccagagggct ggcgacgctc gcctatggga gatcgcggtg
     2401 ctgttccatc tgcgcgatgc gttccgctcc ggagatgtct ggcttactag gtcccggcgc
     2461 tatggcgatc tgaaacacgc actcgttccg gcacaatcca tcgcggaagg cggtcgtctc
     2521 gctgtgccat tgcggccgga ggaatggctg gcagaccggc aagctcgcct cgacatgcgg
     2581 ttgcgcgagc ttggccgtgc cgctcgcgca ggcacgatcc cgggcgggtc gattgaaaac
     2641 ggcgttctgc atatcgagaa actcgaagcc gccgcgccga caggcgccga agatctggtg
     2701 ctcgatctct acaagcagat cccgcccacg cgcatcaccg atctcctgct ggaggtggat
     2761 gcggcgaccg gcttcaccga agcgttcacc catctgcgca caggagcacc ctgcgctgac
     2821 cggatcgggc taatgaacgt tatcttggcg gaagggatca acctcggctt gcgcaaaatg
     2881 gcggatgcga caaacaccca caccttctgg gaattgatcc gcattggacg gtggcatgtc
     2941 gagggcgaag cctatgaccg ggcgctggcc atggtggtcg aggcacaggc agcgttaccc
     3001 atggcccggt tctggggcat gggcacgtcg gcttcgagcg acggacagtt cttcgtcgct
     3061 acagagcaag gtgaggccat gaacctggtc aacgcgaaat atggcaatac cccgggcctg
     3121 aaagcctata gccacgtctc cgaccaatat gcgccgttcg caacccaggt gattcctgca
     3181 acggcaagcg aagcgcctta catcctcgat ggcctgctga tgaacgatgc tggacgccat
     3241 atccgcgagc agttcaccga cacgggcggc ttcaccgatc acgtctttgc cgcatgtgcc
     3301 attctcggct accggttcgc tccgcgcatc cgcgacctgc catccaaacg gctctacgcg
     3361 ttcaatccgt cggccgcccc ggcgcacctg cgagcgttga tcggcggaaa ggtcaaccaa
     3421 gccatgatcg agcgcaattg gcccgacatc ctgcgcatcg ccgccaccat tgctgccggg
     3481 accgtcgcgc caagccagat tctgcggaaa ctcgcctcct atccgcggca gaacgagctc
     3541 gcgacagccc tgcgggaagt cggtcgcgtc gagcgcaccc tgttcatgat cgactggatt
     3601 ctggatgccg aactccaacg gcgtgcccag atcgggctca acaaaggcga agctcatcat
     3661 gcgctgaagc gggcaatcag cttccaccgc cgcggtgaaa tccgcgaccg ttccgccgaa
     3721 ggccagcatt accgcatcgc cggcatgaat ctgctcgccg ccatcatcat cttctggaac
     3781 accatgaagc tcggcgaggt cgttgcaaac cagaaacgcg atggaaagct gctatcgccc
     3841 gatctcttgg cccatgtttc gccgctcgga tgggaacaca tcaatctcac cggagaatat
     3901 cgctggccaa agccttagcg taggattccg ccccctcccg caaacgaccc cgtgatgacc
     3961 ctgcaggcat cccctgagac ccggttaatg cgcgccgagg tgcagcggca ttatccgcac
     4021 atctggcagg agctggaggg gctggcgcag ggactggagg ccactgttga tcaggtcttt
     4081 gcctggaact gccgtggcga tctggtgcgc tcaacgtcgg atggctgtac gacggtggcc
     4141 ggggtaaacg ccgcaggcga gcggattatc gcgcataatg aagacggttt tcctcagtta
     4201 cgggatgaat gcttgctggc taccattact ccgagtcgcg gtctgagctt tacgagtttt
     4261 gcctatccgg ggtcgatttg cggccacacc tttgcggtaa atgaaaaagg tatcgttaac
     4321 acggtgaata acatccgtgc agtgtatcgt ccgcagggat taccgcgtca gatcctggct
     4381 cgcgcctcgc tgaatgcgaa caccctcgac gaggccatca ctatacttac cggccagccg
     4441 cgatccgggg cgtttcacca tacgctcggg cagctgggcg atgcgcggct gttcagcgtt
     4501 gaggccaccg gtcaaggctg ttccgttcta cccctgacga cggtaaccgg gcatgccaac
     4561 catctggtgc atgcggcact ggctggcgtt gagcagatcg ttaccgacag ttcagcgtcg
     4621 cggcagttac gcctcgtgca gtggcgggaa acgcaacctc cgtttgacgc cgcggcggca
     4681 aaaaccattc tctcagatac ccatgacgca gaactgccaa tttaccggct ggctgccgac
     4741 gatccggatg aggagaacac cctcgccacg gcagttttca ccctcgatgc caaccacgtc
     4801 aggtggcaaa ttttcgacat taaccgcgac gatgctaaat ttcatggaga agtgcgtggg
     4861 tgaaatagcc ggtcgtcagt cataaagggc aggggagtac cgttggcccg gcgttcgata
     4921 gtaccgtccg gatactgcca gatatcggcg tccagggaga tgtcctgaag cgcggtgtcc
     4981 ggaatttcag gtttgtgtct ctacaaagac taactatcag aaaaactcat cgagcatcaa
     5041 atgaaactgc aatttattca tatcaggatt atcaatacca tatttttgaa aaagccgttt
     5101 ctgtaatgaa ggagaaaatt caccgaggca gttccatagg atggcaagat cctggtatcg
     5161 gtctgcgatt ccgactcgtc caacatcaat acaacctatt aatttcccct cgtcaaaaat
     5221 aaggttatca agtgagaaat caccatgagt gacgactgaa tccggtgaga atggcaaaag
     5281 cttatgcatt tctttccaga cttgttcaac aggccagcca ttacgctcgt catcaaaatc
     5341 actcgcatca accaaaccgt tattcattcg tgattgcgcc tgagcgagac gaaatacgcg
     5401 atcgctgtta aaaggacaat tactaacagg aatcgaatgc aaccggcgca ggaacgctgc
     5461 cagcgcatca acaatatttt cacctgaatc aggatattct tctaatacct ggaatgctgt
     5521 tttcccgggg agcgcagtgg tgagtaacca tgcatcatca ggagtacgga taaaatgctt
     5581 gatggtcgga agaggcataa atgccgtcag ccagtttagt ctgaccatct catctgtaac
     5641 atcattggca acgctacctt tgccatgttt cagaaacaac tctggcgcat cgggcttccc
     5701 atacaatcga tagattgtcg cacctgattg cccgacatta tcgcgagccc atttataccc
     5761 atataaatca gcatccaggt tggaatttaa tcgcggcctc gagcaagacg tttcccgttg
     5821 aatatggctc ataacacccc ttgtattact gtttatgtaa gcagacagtt ttattgttca
     5881 tgatgatata tttttatctt gtgcaatgta acatcagaga ttttgagaca caacgtggat
     5941 ttgttgaata aatcgaactt ttgctgagtt gaaggatcag atcacgcatc ttcccgacaa
     6001 cgcagaccgt tccgtggcaa agcaaaagtt caaaatcacc aactggccca cctacaataa
     6061 aggggtcgtt tgcgggagag ggcgaaatcc tacgctaagg ctttggccaa cgatattctc
     6121 cggtaagatt gatgtgttcc caggggatag gagaagtcgc ttgatatcta gtatgacgtc
     6181 tgtcgcacct gcttgatcgc ggccgcgata gctagatcgc gttgctcctc ttctccatcc
     6241 gcgttccaag ctgcggaaag gcacccataa gcgtacgcct ggtcgagcag gcgacgcgga
     6301 tcgacgtcca gcgcacgaga gaatgcgtcc gccatctgtg caatgcgtct aggatcgaga
     6361 caaaggtcgt ctctgtcagc cggatcgtag aacatattgg cggcgccaaa gcccacttca
     6421 ccgaccagac cgacgggatc tatcaccagc cagccgcgac tggagaacat gatgttttca
     6481 tgatgcagat cgccatgtag cccacgcagt tccgaggcat tgctcatcat ttgatcggct
     6541 ataatcgccg cgtggacgta gtcagtttga caacctgcgt tttgatcatc gcgcgcccgc
     6601 tgaaacaaag ctgcaaagcg atcccggatc gggagaaggg cagaaggcag gggttcctca
     6661 gatgcggcat acagcttcgc cattagttcc gctgcaattt cggtcgcctg gtagtcgccg
     6721 tgctcggcaa cgatgtgaga gagcattcgc tccccggcat attcgagcaa catcagattg
     6781 ttctcacgac cgagcaaccg gactgctccc ctcccattgc gccataccag atagtcggcc
     6841 ccgcgcagtt catcagcaat gtcttctata ggtttcaatc ccttgacgat tgcaggagtc
     6901 ccgtctggca atgaaacttt ccaaacgagg ctggaaaagg tgtccgcaat gagaacaggt
     6961 tgcgaaacgt gccaatgagc aggaaaaaca ggcggcatga acatcaaccc caagtcagag
     7021 ggtccaatcg cagatagaag gcaaggcgtt cgcggtcggg ggcttcgatc cccaatacat
     7081 tgaataggac agcgaaggcg cgctctgctt catctggcgc tgcccagttc tcttcggcgt
     7141 tagcaatcat gagtgccaaa tcggcatagc gatctgctgt tccgagccgc ccaaggtcga
     7201 tcagacccgt gcattgaaga gttttagggt ccaccatgaa gttcggcatg cagggatcac
     7261 catggcaaac aaccatatcg gtgcgctctt ggtcgagccg caccggtagc tctcgttcga
     7321 cacgagccaa aagatcgagc tgcggcgtac tcttgtcctc gtccggtaag aagtcgggat
     7381 tgacggcatt gcgggacacc acatcaacgg cgcgtccgaa cattcgcgac agcctgcgct
     7441 caaacggaca ttgatcaacc gataggctgt gaacagcgcc aagttgctgc cccattgacg
     7501 gccacgcttt gagcaaatcc gctccagaca gatcagccgc cggtactccc ggaattgccg
     7561 ttatcaccaa gcatgcaccc tcctgttcct cctgccagtt gatcacctcg gggcaagcca
     7621 cacctcgacc tttgagccaa atgaggcggt cacgctctcc agcgagctca ccgcggcggg
     7681 aagcaggtgc gattttcgcg aaggcatgcc cgtcaccacg tcgaaaaaca aaatcaccag
     7741 attctccgcc tctgacaggc aaccagtcag aatgcgattc accaaaaaaa atattagttc
     7801 gattcaatgg aggttccttc agttttctga tgaagcgcgg aggtggctca acctgcgaaa
     7861 agaaacgagt tgctacgtaa gtccgagaac atgctttcca tggtcttgca ccggttgtgt
     7921 tccggtctat ctctcatttt aagcggcttt tttctcaaat gccaccggcg atttccagcc
     7981 gagt
//
LOCUS       DAPGUL010000173         7955 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.176, whole genome shotgun sequence.
ACCESSION   DAPGUL010000173 DAPGUL010000000
VERSION     DAPGUL010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7955)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7955)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7955
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.176"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            1..813
                     /locus_tag="RHX21_004347"
                     /pseudo
     CDS             1..813
                     /locus_tag="RHX21_004347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001560258.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="DUF2713 family protein"
     gene            1177..2214
                     /gene="dusA"
                     /locus_tag="RHX21_004348"
     CDS             1177..2214
                     /gene="dusA"
                     /locus_tag="RHX21_004348"
                     /EC_number="1.3.1.-"
                     /EC_number="1.3.1.91"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine(20/20a) synthase DusA"
                     /protein_id="HDV1989442.1"
                     /translation="MHGNSEMQKINQTSAMPEKTDVHWSGRFSVAPMLDWTDRHCRYF
                     LRLLSRNTLLYTEMVTTGAIIHGKGDYLAYSEEEHPVALQLGGSDPAALAQCAKLAEA
                     RGYDEINLNVGCPSDRVQNGMFGACLMGNAQLVADCVKAMRDVVSIPVTVKTRIGIDD
                     QDSYEFLCDFINTVSGKGECEMFIIHARKAWLSGLSPKENREIPPLDYPRVYQLKRDF
                     PHLTMSINGGIKSLEEAKAHLQHMDGVMVGREAYQNPGILAAVDREIFGSSDTDADPV
                     AVVRAMYPYIERELSQGTYLGHITRHMLGLFQGIPGARQWRRYLSENAHKAGADINVL
                     EHALKLVADKR"
     gene            2348..2590
                     /gene="pspG"
                     /locus_tag="RHX21_004349"
     CDS             2348..2590
                     /gene="pspG"
                     /locus_tag="RHX21_004349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313059.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response protein PspG"
                     /protein_id="HDV1989443.1"
                     /translation="MLELLFVFGFFVMLMVTGVSLLGIIAALVVATAIMFLGGMLALM
                     IKLLPWLLLAIAVVWVIKAIKAPKVPKYQRYDRWRY"
     gene            complement(2756..3739)
                     /locus_tag="RHX21_004350"
     CDS             complement(2756..3739)
                     /locus_tag="RHX21_004350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone oxidoreductase"
                     /protein_id="HDV1989444.1"
                     /translation="MATRIEFHKHGGPEVLQAVEFTPADPAENEIQVENKAIGINFID
                     TYIRSGLYPPPSLPSGLGTEAAGIVSKVGSGVKHIKAGDRVVYAQSALGAYSSVHNIN
                     ADKAAILPAAISFEQAAASFLKGLTVYYLLRKTYEIKPDEQFLFHAAAGGVGLIACQW
                     AKALGAKLIGTVGTAQKAQSALKAGAWQVINYREENLVERLKEITGCKKVRVVYDSVG
                     RDTWERSLDCLQRRGLMVSFGNSSGAVTGVNLGILNQKGSLYVTRPSLQGYITTREEL
                     TEASNELFSLIASGVIKVDVAEQQKYPLKDAQRAHEILESRATQGSSLLIP"
     gene            3822..5237
                     /gene="dnaB"
                     /locus_tag="RHX21_004351"
     CDS             3822..5237
                     /gene="dnaB"
                     /locus_tag="RHX21_004351"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HDV1989445.1"
                     /translation="MAGNKPFNKQQAEPRERDPQVAGLKVPPHSIEAEQSVLGGLMLD
                     NERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGG
                     FAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDL
                     AESRVFKIAESRANKDEGPKNIADVLDATVARIEQLFQQPHDGVTGVNTGYDDLNKKT
                     AGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASL
                     SRVDQTKIRTGQLDDEDWARISGTMGILLEKRNIYIDDSSGLTPTEVRSRARRIAREH
                     GGIGLIMIDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQR
                     ADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVR
                     LTFNGQWSRFDNYAGPQYDDE"
     gene            5290..6369
                     /gene="alr"
                     /locus_tag="RHX21_004352"
     CDS             5290..6369
                     /gene="alr"
                     /locus_tag="RHX21_004352"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDV1989446.1"
                     /translation="MQAATVVINRRALRHNLQRLRELAPASKMVAVVKANAYGHGLLE
                     TARTLPDADAFGVARLEEALRLRAGGITKPVLLLEGFFDARDLPTISAQHFHTAVHNE
                     EQLAALEEASLDEPVTVWMKLDTGMHRLGVRPEQAEAFYHRLTQCKNVRQPVNIVSHF
                     ARADEPKCGATEKQLAIFNTFCEGKPGQRSIAASGGILLWPQSHFDWVRPGIILYGVS
                     PLEDRSTGADFGCQPVMSLTSSLIAVREHKAGEPVGYGGTWVSERDTRLGVVAMGYGD
                     GYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPQAQDKAGDPVILWGEGLPVERI
                     AEMTKVSAYELITRLTSRVAMKYVD"
     gene            6622..7815
                     /gene="tyrB"
                     /locus_tag="RHX21_004353"
     CDS             6622..7815
                     /gene="tyrB"
                     /locus_tag="RHX21_004353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transaminase"
                     /protein_id="HDV1989447.1"
                     /translation="MFQKVDAYAGDPILTLMERFKEDPRSDKVNLSIGLYYNEDGIIP
                     QLQAVAEAEARLNAQPHGASLYLPMEGLNSYRHAIAPLLFGADHPVLQQQRVATIQTL
                     GGSGALKVGADFLKRYFPESGVWVSDPTWENHVAIFAGAGFEVSTYPWYDEATNGVRF
                     NDLLATLKTLPARSIVLLHPCCHNPTGADLTNDQWDAVIEILKSRELIPFLDIAYQGF
                     GAGMEEDAYAIRAIASAGLPALVSNSFSKIFSLYGERVGGLSVLCEDAEAAGRVLGQL
                     KATVRRNYSSPPNFGAQVVAAVLNDEALKASWLAEVEEMRTRILAMRQELVKVLSTEM
                     PERNFDYLLNQRGMFSYTGLSAAQVDRLREEFGVYLIASGRMCVAGLNTANVQRVAKA
                     FAAVM"
BASE COUNT         1948 a         1883 c         2064 g         2060 t
ORIGIN      
        1 ttattgcaaa aatagatttg tttattcaac gaatcacgca taatttatgg catgcacgta
       61 aaaaaatgtg tttttaattg agcaaataaa tgatctcaaa atgtgggtca ataagtatat
      121 tgacgattgc actgatgagg atttaaacga tcgtgacttt attgcatcag ttgttgaccg
      181 ggctattttt catttcgcga ttaatagtat atgtaatcct ggggataata aagatgcgac
      241 tcccattgaa cgatgtactt ttgatgtaga aactaagaat ggccttccct ccacggttca
      301 gctattttat gaggaatcta aggataatga acctttagcg aatatacatt ttcaagcaat
      361 aggttctggt tttttaacgt ttgttaatgc ctgccaggaa catgatgaca acagcttaaa
      421 attatttgct tcgctgttaa tttcaatttc atattctagt gcctacacag atttagccgg
      481 agcagaaaaa gtgaatatta atgaatataa tgagaactat ctgacagctc agtttgaaga
      541 attatctcaa cgtgatatga agaagtacct gggagagatg aagcatctgg cggaccgggg
      601 gggatgaaat ttgatgacta tctggataaa atgtcacttc tggtgaatga aggaaagctc
      661 gaacctgata ttttaagcaa aatgcgagat gctgcaccga aattaattga ctttgctaag
      721 tcgtttgacc caaactcaaa ggaaaagatt aaaatactta cagatacttc taatttaatt
      781 tatgatttgt tcggggttaa atcggcgaaa taatatgtga agttcttcga tggtatggaa
      841 ggcattacat aaaagaacct aatacttatt gggttctttt ttcttctatc agtgccatta
      901 gcaggaagag atatcaccgg agtttaatgt gtgatttttt atttatcgtc gaacctggat
      961 tgtttatcat tgtccttaac aaggctaacg gctaataaga ttatttccat cacttcgtga
     1021 gagcttcatg ccttgatttg atctcaattt tcttttgcaa tgagacaggc gcttcctgtt
     1081 gttatggtat agtaccccgc tattgagcct cctgaacagt gatgctgaat aacataaccc
     1141 aatgatatat cgataaaata atctctacat ttgaaaatgc acggtaattc tgaaatgcaa
     1201 aaaatcaacc aaaccagcgc aatgcctgaa aaaactgacg ttcactggag tggtcggttt
     1261 agcgttgcac caatgctcga ctggacggac agacattgcc gctatttctt gcgtctgctt
     1321 tcccgcaata cgttgctgta taccgaaatg gtgaccacag gggcgattat tcacggtaaa
     1381 ggtgattacc tggcgtacag tgaagaagaa catccggtag cgttgcaact cggcggtagc
     1441 gatccggcgg cgctggcgca gtgtgcaaag ctggcagaag cgcgcggata tgatgagatc
     1501 aacctgaatg tcggctgccc gtctgaccgg gtgcagaacg gcatgtttgg tgcgtgtctg
     1561 atgggtaatg cgcagctggt tgccgactgc gtgaaagcga tgcgcgatgt ggtgtcgatt
     1621 ccagtgacgg tgaaaacgcg tattggcatc gatgaccagg acagctatga atttctctgc
     1681 gatttcatca acaccgtttc cggcaaaggc gagtgtgaga tgtttatcat ccacgcacgt
     1741 aaagcctggc tttcggggtt aagcccgaaa gaaaaccgtg aaatcccgcc gctcgattat
     1801 ccgcgtgtgt atcaactgaa gcgtgacttt ccgcatctga caatgtcgat taacggtggt
     1861 atcaagtcgc tggaagaggc caaagcacac ctgcaacata tggatggcgt gatggtcggg
     1921 cgcgaggcgt atcagaatcc gggtattctg gcggcggtag accgggagat ctttggttcc
     1981 tcggataccg atgccgatcc ggtggcggta gtgcgcgcca tgtatccgta cattgagcgt
     2041 gaactcagcc aggggacgta tctcggccat attacccggc atatgttggg cttgttccag
     2101 ggtattcctg gcgcgcggca gtggcggcgt tatttaagtg aaaatgccca taaagcgggt
     2161 gcagacatta atgtgctgga acacgcgctc aaactggtgg cggataagcg ttaacttttc
     2221 accaaaaagt agtcaaattc accacgccct gcgcaccgtc gcggggcgtt ttgctgttaa
     2281 atcaatagat tatttttggc atgattcttg taatgccagc aagagatttc atatttggga
     2341 gagcatcatg ctggaactac tttttgtgtt tggctttttt gtcatgctga tggtcaccgg
     2401 cgtttcgttg ctgggcatta tcgccgcgct ggttgtggcg acggccatta tgttcctcgg
     2461 cggtatgctg gcattgatga ttaagttgct gccgtggtta ctactggcga ttgcggtggt
     2521 gtgggttatt aaggcgatta aagcaccaaa agtgccgaaa tatcagcgtt atgaccgctg
     2581 gcgttactaa gggattgtgc ggatgatcac aacctaaggt tttatcctta gaacaaaata
     2641 ggaattgata atcaaatctg tcactattgc gcctctaaca gattcatcgt gctgtaccct
     2701 acatacagcc gaactataaa aagaaagggc ttcccaggtg gaagccctat ttcttttatg
     2761 gaatcagcag gctggaacct tgcgtcgccc ggctttccag aatctcatgc gcacgctgcg
     2821 catccttcag cggatatttc tgctgctcgg cgacatcgac cttaatcaca ccgctggcaa
     2881 tcaaagagaa cagttcatta ctggcctcgg ttaattcctc ccgcgtggtg atatagcctt
     2941 gcagggaagg gcgtgtcaca tacaacgagc ctttttgatt gagaatgcct aagttcacac
     3001 cggtaaccgc acctgatgag ttgccaaaac tgaccattaa gccgcggcgt tgcaggcaat
     3061 ccagcgaccg ttcccaggtg tctctgccca cggaatcgta cactacgcgc actttcttac
     3121 agccggtgat ctctttcaat cgctcgacca gattctcttc acgatagtta ataacctgcc
     3181 acgcgccggc ttttagcgcg ctctgcgctt tttgcgcggt tcctacggtg ccgataagtt
     3241 tcgcgcccag ggcttttgcc cactggcagg caattaagcc aacgccgcca gccgctgcgt
     3301 ggaacaggaa ctgttcatcg ggtttaattt cataggtttt gcgcagcaga taataaaccg
     3361 ttaagccttt caggaaagat gctgcagctt gttcaaaaga aattgccgca ggcagaatcg
     3421 ccgctttatc cgcattaatg ttatgcacag agctgtaagc gcctaacgcc gactgcgcat
     3481 agactacacg atcgcctgcc ttaatatgct ttacaccact gccgacttta ctcacgatgc
     3541 ctgccgcttc ggtacctaat ccgctgggta gtgatggcgg cgggtaaagg ccgctgcgga
     3601 tatacgtgtc gataaaattg atgccgatgg ctttattttc gacctggatt tcattctctg
     3661 ccggatcggc aggagtgaac tctacggctt gaagtacttc cgggccaccg tgcttgtgaa
     3721 attcaattcg tgttgccatg tgtcctccag aacgtatcgt cagggtctgc ttcatatggt
     3781 aaagtttcga cccattcttt atctcggtaa ctccattcac tatggcagga aataaaccct
     3841 tcaacaaaca gcaggctgaa ccccgcgaac gcgatccaca agttgccggg ctgaaagtgc
     3901 ctccgcactc gatcgaagcg gagcagtcgg tgttgggcgg tttaatgctg gataacgaac
     3961 gctgggacga tgtagccgag cgtgtggtgg cagacgattt ttacacccgc ccacaccgcc
     4021 atatctttac tgaaatggcg cgtttgcagg aaagcggtag tcctatcgat ctgattaccc
     4081 ttgcggaatc gctggaacgc caggggcaac tcgatagcgt cggtggtttt gcttatctgg
     4141 cagagctgtc aaaaaatacg ccaagtgcgg cgaacatcag tgcctatgcg gacatcgtgc
     4201 gtgaacgtgc cgttgtccgt gagatgatct cggttgcgaa tgagattgct gaagccggtt
     4261 ttgatccgca ggggcgtacc agcgaagatc tgctggacct tgctgaatcc cgcgtcttta
     4321 aaattgccga aagtcgtgca aacaaagacg aagggccgaa gaacatcgcc gatgtgctcg
     4381 acgcaaccgt ggcgcgtatt gagcagttgt ttcagcagcc acacgatggc gttaccggag
     4441 taaacaccgg ttatgacgat ctcaacaaaa aaaccgctgg cttgcagccg tcggatttga
     4501 tcatcgtcgc cgcgcgtccg tcgatgggta aaacaacatt tgcgatgaac ctcgtcgaaa
     4561 acgcggcgat gttgcaggat aaaccggtac ttatcttctc gctggagatg ccttcagaac
     4621 agattatgat gcgttctctg gcgtcgctgt cgcgcgttga ccagactaaa atccgtaccg
     4681 ggcagctcga tgatgaagac tgggcgcgca tttccggcac catgggtatt ttgctcgaaa
     4741 aacgcaatat ctatatcgat gactcctccg gcctgacgcc aacggaagtg cgttcccgcg
     4801 cacgccgtat tgcccgtgaa cacggcggca tcgggcttat catgatcgac tacctgcaac
     4861 tgatgcgcgt accggcgctt tccgataacc gtacgctgga aattgcagaa atctcccgct
     4921 cgctgaaagc actggcgaaa gaactgaacg tgccggtggt ggcgctgtcc cagttgaacc
     4981 gttctctgga acaacgtgcc gacaaacgcc cggtcaactc cgacctgcgt gaatctggct
     5041 ctatcgagca ggatgcggac ttgatcatgt ttatctatcg tgatgaggtg tatcacgaaa
     5101 acagtgattt aaaaggcatc gcggaaatta ttatcggtaa acaacgtaac ggcccaatcg
     5161 ggacggtacg cctgaccttt aacggtcaat ggtcgcgctt cgacaactat gcggggccgc
     5221 agtacgacga cgaataataa ttattttatg aattaggtaa ttaaagcaaa cacttatcaa
     5281 ggaacacaaa tgcaagcggc aactgttgtg attaaccgcc gcgctctgcg acacaacctg
     5341 caacgtcttc gtgaactggc ccctgccagt aaaatggttg cggtggtgaa agcgaacgct
     5401 tatggtcacg gtcttcttga gaccgcgcga acgctccccg atgctgacgc ctttggcgta
     5461 gcccgtctcg aagaagctct gcgactgcgt gcggggggaa tcaccaaacc tgtactgtta
     5521 ctcgaaggct tttttgatgc cagagatctg ccgacgattt ctgcgcaaca ttttcatacc
     5581 gccgtgcata acgaagaaca gctggctgcg ctggaagagg ctagcctgga cgagccggtt
     5641 accgtctgga tgaaactcga taccggtatg caccgtctgg gcgtaaggcc ggaacaggct
     5701 gaggcgtttt atcatcgcct gacccagtgc aaaaacgttc gtcagccggt gaatatcgtc
     5761 agccattttg cgcgcgcgga tgaaccaaaa tgtggcgcaa ccgagaaaca actcgctatc
     5821 tttaatacct tttgcgaagg caaacctggt caacgttcca ttgccgcatc gggtggcatt
     5881 ctgctgtggc cacagtcgca ttttgactgg gtgcgcccgg gcatcattct ttatggcgtc
     5941 tcgccgctgg aagatcgctc caccggtgcc gattttggct gtcagccagt gatgtcacta
     6001 acctccagcc tgattgccgt gcgtgagcat aaagccggag aacctgttgg ttatggtgga
     6061 acctgggtaa gcgaacgtga tacccgtctt ggcgtagtcg cgatgggcta tggcgatggt
     6121 tatccgcgcg ccgcgccgtc cggtacgcca gtgctggtga acggtcgcga agtaccgatt
     6181 gtcgggcgcg tggcgatgga tatgatctgc gtagacttag gtccacaagc gcaggacaaa
     6241 gccggggatc cggtcatttt atggggcgaa ggtttgcccg tagaacgtat cgctgaaatg
     6301 acgaaagtaa gcgcttacga acttattacg cgcctgactt caagggtcgc gatgaaatac
     6361 gtggattaat cgttctgtaa tatttgattg tctgtgccgg atgcggcgtg aatgccttat
     6421 ccggccaata aaatcctaaa aattcaataa gttgatgttc tttcatgctc ttataaaggt
     6481 cgtgcctctg gcggatgtac gtttgtcatg agtctcactc tgttgctaat tgccgttcgc
     6541 tcctgaacat ccactcgatc ttcgccttct tccggtttat tgtgttttaa ccacctgccc
     6601 gtaaacctgg agaaccatcg cgtgtttcaa aaagttgacg cctacgctgg cgacccgatt
     6661 cttacgctta tggagcgttt taaagaagac cctcgcagcg acaaagtgaa tttaagtatc
     6721 ggtctgtact acaacgaaga cggaattatt ccacaactgc aagccgtggc ggaggcggaa
     6781 gcgcgcctga atgcgcagcc tcatggcgct tcgctttatt taccgatgga agggcttaac
     6841 agctatcgcc atgccattgc gccgctgctg tttggtgcgg accatccagt actgcaacaa
     6901 cagcgcgtag caaccattca aacccttggc ggctcagggg cattgaaagt gggcgcggat
     6961 ttcctgaaac gctacttccc ggaatcaggc gtctgggtca gcgatcctac ctgggaaaac
     7021 cacgtagcaa tattcgccgg ggctggattc gaagtgagta cttacccctg gtatgacgaa
     7081 gcgactaacg gcgtgcgctt taatgacctg ttggcgacgc tgaaaacatt acctgcccgc
     7141 agtattgtgt tgctgcatcc atgttgccac aacccaacgg gtgccgatct cactaatgat
     7201 cagtgggatg cggtgattga aattctcaaa tcccgcgagc ttattccatt cctcgatatt
     7261 gcctatcaag gatttggtgc cggtatggaa gaggatgcct acgctattcg cgccattgcc
     7321 agcgctggat tacccgctct ggtgagcaat tcgttctcga aaattttctc cctttacggc
     7381 gagcgcgtcg gcggactttc tgttctgtgt gaagatgccg aagccgctgg ccgcgtactg
     7441 gggcaattga aagcaacagt tcgccgcaac tactccagcc cgccgaattt tggtgcgcag
     7501 gtggtggctg cagtgctgaa tgacgaggca ttgaaagcca gctggctggc ggaagtagaa
     7561 gagatgcgta ctcgcattct ggcaatgcgt caggaactgg tgaaggtatt aagcacagag
     7621 atgccagaac gcaatttcga ttatctgctt aatcagcgcg gcatgttcag ttataccggt
     7681 ttaagtgccg ctcaggttga ccgactacgt gaagaatttg gtgtctatct catcgccagc
     7741 ggtcgcatgt gtgtcgccgg gttaaatacg gcaaatgtac aacgtgtggc aaaggcgttt
     7801 gctgcggtga tgtaatgcag gaaagcaggc tggagctacc cagcctgcag tgaaattaaa
     7861 ctgtcgtcgc tttcactctt tctttataga tgattttttt gatgccatcg ttctacgtga
     7921 gagataataa acgttattag ttcttttatt gttaa
//
LOCUS       DAPGUL010000174         7892 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.177, whole genome shotgun sequence.
ACCESSION   DAPGUL010000174 DAPGUL010000000
VERSION     DAPGUL010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7892)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7892)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7892
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.177"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            1..1071
                     /locus_tag="RHX21_004354"
                     /pseudo
     CDS             1..1071
                     /locus_tag="RHX21_004354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418441.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="ShET2/EspL2 family type III secretion system
                     effector toxin"
     gene            complement(1040..2776)
                     /gene="aceK"
                     /locus_tag="RHX21_004355"
     CDS             complement(1040..2776)
                     /gene="aceK"
                     /locus_tag="RHX21_004355"
                     /EC_number="2.7.11.5"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional isocitrate dehydrogenase
                     kinase/phosphatase"
                     /protein_id="HDV1989448.1"
                     /translation="MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQ
                     QAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAAFLLRVKEHYTRLLPDYPRFEIAESF
                     FNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDL
                     PLRLRWQNKSRDIHYIIRHLTETLGTDNLAESHLQVANELFYRNKAAWLVGKLITPSG
                     TLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILP
                     GKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRV
                     FKVIKDKFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMEL
                     LLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAA
                     ANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDELASEPWYSV
                     SPGDVFPEEFRHWLCADPRIGPLFEEMHADLFRADYWRALQNRIREGHVEDVYAYRRR
                     QRFSVRYGEMLF"
     gene            complement(3057..4361)
                     /gene="aceA"
                     /locus_tag="RHX21_004356"
     CDS             complement(3057..4361)
                     /gene="aceA"
                     /locus_tag="RHX21_004356"
                     /EC_number="4.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate lyase"
                     /protein_id="HDV1989449.1"
                     /translation="MKTRTQQIEELQKEWTQPRWEGITRPYSAEDVVKLRGSVNPECT
                     LAQLGAAKMWRLLHGESKKGYINSLGALTGGQALQQAKAGIEAVYLSGWQVAADANLA
                     ASMYPDQSLYPANSVPAVVERINNTFRRADQIQWSAGIEPGDPRYVDYFLPIVADAEA
                     GFGGVLNAFELMKAMIEAGAAAVHFEDQLASVKKCGHMGGKVLVPTQEAIQKLVAARL
                     AADVTGVPTLLVARTDADAADLITSDCDPYDSEFITGERTSEGFFRTHAGIEQAISRG
                     LAYAPYADLVWCETSTPDLELARRFAQAIHAKYPGKLLAYNCSPSFNWQKNLDDKTIA
                     SFQQQLSDMGYKFQFITLAGIHSMWFNMFDLANAYAQGEGMKHYVEKVQQPEFAAAKD
                     GYTFVSHQQEVGTGYFDKVTTIIQGGTSSVTALTGSTEESQF"
     gene            complement(4391..5992)
                     /gene="aceB"
                     /locus_tag="RHX21_004357"
     CDS             complement(4391..5992)
                     /gene="aceB"
                     /locus_tag="RHX21_004357"
                     /EC_number="2.3.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate synthase A"
                     /protein_id="HDV1989450.1"
                     /translation="MTEQATTTDELAFIRPYGEQEKQILTAEAVEFLTELVTHFTPQR
                     NKLLAARIQQQQDIDNGTLPDFISETASIRDTDWKIRGIPADLQDRRVEITGPVERKM
                     VINALNANVKVFMADFEDSLAPDWNKVIDGQINLRDAVNGTISYTNEAGKIYQLKPNP
                     AVLICRVRGLHLPEKHVTWRGEAIPGSLFDFALYFFHNYQALLAKGSGPYFYLPKTQS
                     WQEAAWWSEVFSYAEDRFNLPRGTIKATLLIETLPAVFQMDEILHALRDHIVGLNCGR
                     WDYIFSYIKTLKNYPDRVLPDRQAVTMDKPFLNAYSRLLIKTCHKRGAFAMGGMAAFI
                     PSKDEERNNQVLNKVKADKALEANNGHDGTWIAHPGLADTAMAVFNDILGSRKNQLEV
                     MREQDVPITADQLLAPCDGERTEEGMRANIRVAVQYIEAWISGNGCVPIYGLMEDAAT
                     AEISRTSIWQWIHHQKTLSNGKPVTKALFRQMLGEEMKVIASELGEERFSQGRFDDAA
                     RLMEQITTSDELIDFLTLPGYRLLA"
     gene            complement(6261..7190)
                     /gene="metA"
                     /locus_tag="RHX21_004358"
     CDS             complement(6261..7190)
                     /gene="metA"
                     /locus_tag="RHX21_004358"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HDV1989451.1"
                     /translation="MPIRVPDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLM
                     PKKIETENQFLRLLSNSPLQVDIQLLRIDSRESRNTPAEHLNNFYCNFEDIQEQNFDG
                     LIVTGAPLGLVEFNDVAYWPQIKQVLEWSKDHVTSTLFVCWAVQAALNILYGIPKQTR
                     TDKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGD
                     AYLFASKDKRIAFVTGHPEYDAQTLAQEYFRDVEAGLGPEVPYNYFPHNDPQNTPRAS
                     WRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD"
     gene            7347..7790
                     /locus_tag="RHX21_004359"
     CDS             7347..7790
                     /locus_tag="RHX21_004359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDV1989452.1"
                     /translation="MVISIRRSQHEEGEELVAIWCRSVDATHDFLSAEYRAELEELVR
                     SFLPEAPLWVAVNERDQPVGFMLLSGQHMDALFIDPDVRGCGVGRMLVEHALSMAPEL
                     TTNVNEQNEQAVGFYKKVGFKVTGRSEVDDLGKPYPLLNLAYVGE"
BASE COUNT         1970 a         1982 c         1989 g         1951 t
ORIGIN      
        1 gaatgttgat tacaaacccc atcaagatga ttactcttca gctgaaaaat ttctcacgca
       61 cttcaacaaa aaatgcaaaa accagacttt ggcgttggtt tccagccgtc ctgaggggcg
      121 ttacgttgct gcctgtggtg atttcgggct agttatgaag gcatatttcg acaagatgga
      181 atcaaatggc atcagtgtta tggcagccat attattggtg gataaccatg ctttgacggc
      241 gcggctaaga ataaagaaca caactgaagg atgtacccat tacgtggttt cggtttatga
      301 tcctaatgtc actaacgata aaataagaat tatgagcgaa agcaaagagg atattaaaca
      361 ctattctctg atggatttta tgaatgtaga ttatagcctc ctgaaatggt caaatgatca
      421 tattattaac caatctgttg caataattcc agcacttccg aaagaacagc tattgatgtt
      481 aaaaggatct gtggatgaaa taacccctcc attatcacct gcaacgatga atttgctaat
      541 ggcaattggt cagaatcacc aacttacgca actgatgatt caactccaga aaatgccaga
      601 actacataga acagaaatgt tgactgccta taatagtgga catatgaacg ttattaatac
      661 tatttttaac gcattaccca ctctttttaa tacgtttaaa ttcgataaaa aaatatgaag
      721 cccctcctcc tggcaaataa ttctaatgaa tatcccggtt tgttttcagc gatacagcat
      781 aaacaacaaa acgttgtaga gacggtttat cttgctttat ctgaccatgc acgcctgttt
      841 ggatttaccg ctgaagatat tatggatttt tggcaacaca aagccccaca aaaatactct
      901 gcctttgagt tggcttttga attgggtcac cgggttattg ctgaattaat ccttaataca
      961 ttaaataaga tggctgaaag ctttggcttt acggataacc ctcgatacat tgcggagaaa
     1021 aattatatgg aagctttact caaaaaagca tctccccata ccgtacgcta aatctttgcc
     1081 tgcgccgata cgcataaaca tcttccacat gcccttcacg tatgcggttt tgtagtgcgc
     1141 gccagtaatc agcgcggaac aggtcggcgt gcatctcttc aaacagcgga ccaatacgcg
     1201 ggtcggcgca tagccagtgg cgaaactctt ccgggaaaac atcgcccggc gagacgctgt
     1261 accacggttc gctggcaagt tcgtcttccg gatagcgcgg cggcgggatg tcgcggaaat
     1321 tcacttccgt catgtagcaa atttcatcgt aatcataaaa aaccacacgc ccgtgacggg
     1381 tgacaccgaa gtttttaaac agcatgtcgc caggaaaaat gttagcagcg gcaagctggc
     1441 gaatagcgtt accgtattct tcaatggcgt cgcgcaactg ctgaccttcc acttgttcca
     1501 gccagatatt gagcggcacc atccgccgct cgatatagag atggcgaatt acaatctgct
     1561 caccaagatc ggtgattttt tccgctgctt cctggagcag taattccatt aatgccgggg
     1621 aaatatgccg cttctccagc acaaagtttt caaactcctg ggtgtccgcc attcggccca
     1681 cacggtcgtg ctctttcacc agttgatagc aggcacgaac gtgagcggca gacatctctt
     1741 tctgcggcgc gaacttgtct ttgatgactt tgaatacccg atcaaagccc ggcagcgtaa
     1801 ataccaacat caccattcca cgaatacccg gcgcttcaat gaactgctca ttacagccct
     1861 gtagataaac gagatattcg cggtagcttt cggttttggc gtgcttctgg cagccgatag
     1921 ccatatacaa ttcagcagtg gttttacctg gcagaatttc ccgtagccac tcgaccagcg
     1981 ctgcgggcag cggtgcataa accataaaat aagaacgcgc aaagccaaaa acaatgctcg
     2041 cttcggcggt cgtcgtcagg caggtatcaa taaataactc gccgtcgtcc gtctggtgga
     2101 tcggcagtaa gaagggcaac gtgccggaag gcgtgatcag tttgcccacc agccaggcgg
     2161 ctttattgcg gtaaaacagt tcgttcgcca cctgtaaatg actttccgcg aggttgtctg
     2221 tccccagcgt ttccgtcaga tggcgaatga tgtaatgaat gtcacggctt ttattctgcc
     2281 agcgcaggcg cagcggcagg tcgctgataa cgcgcatcag tagagattcc cagccgtgat
     2341 cggggtgaaa gtctttcgcc agcgggcggg gaatggtacg aaagcggcgc tctggctgag
     2401 agctaaagat aaaaagccgc tcgggagtaa gcgagcggtg gtcaaataac cgacagtaca
     2461 cggagttaaa aaagctctcc gcaatctcga agcgcgggta atccggcaac agccgcgtgt
     2521 aatgctcttt aacgcgcagt aaaaatgccg cgtccgtact ttggccgtta gtaatgcagc
     2581 gcagttgctc cacgaccaga ccaacgtgat gatcgtaaag atggatacgg tttttcatcg
     2641 cctgctggac agcatgccag tcggcctgtt cgaaacgctg ctgcgccccg gaagtcactt
     2701 cgaggaatcg accatactga gcgtcgaagc cttgcaaaat ggtttgagca atcagtaatt
     2761 ccaggccacg cggcatttag cgccctcatc aggagcagag aattgccgga tgcggcgtaa
     2821 acgccttatc cagcctacgt tcggcaacgg ttgtaggcat gataagacgc gcaagcgtcg
     2881 catcaggcat cgtgcaccga ttgccggatg cggcgtaaat gccttatccg gcctacgttc
     2941 ggcaacggct gtaggcatga taagacgcgc aagcgtcgca tcaggcatcg tgcaccgatt
     3001 gccggatgcg gcgtgaacgc cttatccggc ctacagtcag caacggttgt tgttgcttag
     3061 aactgcgatt cttcagtgga gccggtcagc gcggtgactg aagacgtgcc gccctgaata
     3121 atagtcgtca ctttatcgaa gtaacctgta cccacttcct gctggtgaga tacgaaggta
     3181 tagccatctt tcgcggcggc aaattccggc tgctgcactt tctcaacgta gtgcttcata
     3241 ccctcgccct gggcataggc gtttgccagg tcaaacatgt tgaaccacat gctgtggata
     3301 cctgccaggg tgatgaactg gaacttgtag cccatatccg acagctgctg ctggaagctg
     3361 gcaatagttt tgtcgtcgag gtttttctgc cagttgaacg acggcgagca gttataagcc
     3421 agcagtttgc ccggatattt cgcgtggata gcttgtgcaa agcgacgcgc cagttccaga
     3481 tccggcgtgg aggtttcaca ccagaccagg tcagcatatg gcgcatacgc caggccacgg
     3541 ctgatcgctt gctcaatgcc cgcatgagta cggaagaagc cttcactggt acgctcgcca
     3601 gtaataaatt cactgtcata cgggtcgcaa tcggaggtaa tcagatccgc cgcatcggca
     3661 tcggtacgag caaccagcag ggttggaacg cccgtcacgt cagctgcaag acgcgccgcg
     3721 accagtttct gaatagcttc ctgagttggc accaaaactt tgccgcccat gtgaccgcat
     3781 ttcttcactg acgccagctg atcttcgaag tgaactgccg ctgcaccggc ttcaatcatc
     3841 gctttcatca gttcaaaggc attcaggaca ccgccaaaac cggcttccgc atcggcaacg
     3901 atcggcagga agtaatcgac atagcgcgga tcgcccggct caatgcctgc ggaccattgg
     3961 atctgatcgg cacgacggaa ggtgttgttg atccgctcca ccacagctgg caccgagttt
     4021 gccggataga gcgactgatc cggatacatg ctggccgcca ggttagcgtc cgccgctacc
     4081 tgccatcccg acagatagac tgcttcaata cccgctttcg cctgttgcag cgcctgaccg
     4141 ccagtcagtg caccgaggct gttgatgtag ccttttttcg actcgccatg cagcagacgc
     4201 cacattttcg ccgcgcccag ttgcgccagg gtgcattcag gattgactga accgcgtaat
     4261 ttcaccacat cttccgcgct gtatgggcga gtaatgcctt cccaacgcgg ttgagtccac
     4321 tctttctgta attcttcaat ttgttgtgta cgggttttca tgtgcagatg ctccatagtt
     4381 atgtggtggt ttacgctaac aggcggtagc ctggcagggt caggaaatca attaactcat
     4441 cggaagtggt gatctgttcc atcaagcgtg cggcatcgtc aaaacgcccc tgggagaaac
     4501 gttcttcgcc cagttcgctg gcaatgactt tcatctcttc acccagcatc tggcggaaca
     4561 aggctttggt caccggtttg ccattgctca acgttttttg atgatggatc cactgccaga
     4621 ttgaggtacg ggaaatttca gccgtcgccg catcttccat caggccataa atcggcacgc
     4681 agccgttgcc ggagatccat gcttcgatgt actgcactgc cacgcgaatg ttggcgcgca
     4741 taccttcttc ggtgcgttca ccatcacaag gtgccagcag ctgatcggca gtaatcggca
     4801 cgtcttgttc gcgcatcact tcaagctgat ttttacggga gccgagaatg tcgttgaata
     4861 ccgccattgc cgtatccgca aggcctgggt gagcaatcca tgtgccatcg tgaccgttat
     4921 tggcttccag cgctttatcc gcttttactt tgttgagcac ctggttattg cgctcttcat
     4981 ctttgctcgg aataaacgct gccatgccgc ccatcgcaaa agcaccgcgt ttatggcagg
     5041 ttttaatcaa caggcgtgag taagcattca ggaatggttt atccatcgtc actgcctgtc
     5101 tgtctggcag gacgcgatcg ggatagtttt tcaacgtttt gatatagctg aagatgtaat
     5161 cccaacgacc gcagttcaga ccaacaatat ggtcacgcag cgcgtgaagg atttcatcca
     5221 tctggaacac ggcgggcagc gtttcaatca gcaacgtcgc cttgatggtg ccgcgcggca
     5281 gattaaagcg atcttctgca tagctgaaga cttcgctcca ccaggccgct tcctgccagg
     5341 actgggtttt cggcagatag aaatagggac cgctgccctt tgccaacagt gcctgatagt
     5401 tgtggaagaa atagagcgca aaatcaaaca ggctaccggg gattgcctca ccacgccagg
     5461 tgacatgttt ttccggcaag tgcagaccgc gtacccgaca aatcaaaacc gctggattgg
     5521 gcttgagctg ataaattttg cctgcttcat tggtatagct gatggtgccg ttaaccgcat
     5581 cgcgcaggtt aatttgcccg tcgatcactt tgttccagtc tggtgccagt gaatcttcga
     5641 aatcggccat aaagactttc acattggcgt tcagtgcgtt gatcaccatc ttgcgctcaa
     5701 ccggaccagt tatctcgact cgacgatctt gtaagtccgc gggaatacca cgaattttcc
     5761 agtccgtatc gcgaatggaa gctgtttccg aaataaaatc aggcaaagtt ccgttatcaa
     5821 tatcttgctg ctgctgaatg cgcgctgcca gaagtttatt gcgttgtggc gtaaaatgcg
     5881 tcaccagctc agtcagaaat tctaccgctt cggcagtaag aatttgcttc tcctgctcgc
     5941 catacggcct tatgaaagcc agttcatcgg ttgttgttgc ctgttcagtc atcgtgcagc
     6001 tcctcgtcat ggatccgaaa acttccccac tgtgaacgaa ggatcgttgt gcgcttttcg
     6061 ttcagcacaa ctaagactac tcatttaaaa tgcaaaatca aaaacaattt ccattttaat
     6121 taaaaatact tgataactta ttgataacaa tatgaataaa atttattcac ctcctgaggt
     6181 gcgtttcgga aataaaaaag gcacccgaag gtgcctgagg taaggtgctg aatcgcttaa
     6241 cgatcgacta tcacagaaga ttaatccagc gttggattca tgtgccgtag atcgtatggc
     6301 gtgatctgat agacgtaata gttgagccag ttggtaaaca gcaaattacc gtgactacgc
     6361 cagctcgctc gcggtgtatt ttgcggatca ttgtgcggga aatagttata cggtacttcc
     6421 gggcctagtc cggcttccac atcgcggaaa tattcctgcg ccagcgtttg cgcatcatat
     6481 tcgggatggc ccgtcacaaa ggcaatgcgc ttatctttgc tggcaaacag atatgcatcc
     6541 ccttcttccg tctctgccag aatttccaga tcggtgtaat cacgaatcaa cgctgccgga
     6601 aagtcagcat agcgcgaatg tggtgccagg aatgaatcat caaagccacg cgtcagaagc
     6661 gcatgaggat ggagaatatg atgctcgtaa acgccagaga gtttgtcggt gcgagtttgc
     6721 ttaggaatgc cgtagaggat attgagcgcg gcctgtaccg cccagcagac aaacagcgtc
     6781 gaggtgacgt gatctttcga ccactccagc acctgtttga tctgcggcca gtaagcgaca
     6841 tcattaaact ccaccaggcc cagcggcgca ccggttacaa tcagaccgtc aaagttctgt
     6901 tcctgaatat cttcaaagtt acagtagaag ttgttcagat gctctgcggg cgtgttgcgc
     6961 gattcacggg aatcgatgcg caacagctga atatcgacct gcaaaggtga gtttgaaagc
     7021 aggcgcagaa actgattttc agtttcaatc ttcttcggca tcaggttaag gatcagaacc
     7081 ttaagtggac gaatttcctg accagacgca cgagaagttg tcatcacaaa gacgttttct
     7141 tcacgcaaga aattgacggc gggtagctcg tccggcacac gaataggcat aacctgatta
     7201 cctcactaca tacgcttata cgtttagaca tccagatagc tgaagataac cagaaaattt
     7261 gccaatgtcg agcctgcatg ttgaaggtga gaaagtttca aggaaaaggc tacgttagaa
     7321 tataagaatg acgaaaagga gagaaaatgg ttattagtat tcgccgctca cagcatgagg
     7381 aaggggagga actcgttgcg atttggtgtc gatctgtcga tgccacccac gattttttat
     7441 cagcagagta tcgggccgag ctggaagagc tggttcgttc ctttctgccg gaagcaccgt
     7501 tgtgggtcgc ggttaatgaa cgggatcagc cggttgggtt tatgttgtta agtgggcagc
     7561 atatggatgc gctgtttatc gatcctgatg tgcgcggctg cggcgtgggt cggatgctgg
     7621 tggagcatgc gctctcgatg gcaccggaac tgacaaccaa cgttaatgag caaaatgagc
     7681 aggcggttgg gttctataag aaggtgggtt ttaaggttac gggacgctct gaggtggacg
     7741 atttggggaa accgtatccg ttgctgaatc tggcgtatgt gggggaataa gccgcccctg
     7801 ccgtgcctgc ccaggctgga gaagacgcgc cagcgtcgca tccgaccttt ttctgcacca
     7861 gcgcaaaaag gcccagtctt ccgactgggc ct
//
LOCUS       DAPGUL010000175         7786 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.178, whole genome shotgun sequence.
ACCESSION   DAPGUL010000175 DAPGUL010000000
VERSION     DAPGUL010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7786)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7786)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7786
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.178"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..450
                     /locus_tag="RHX21_004360"
     CDS             <1..450
                     /locus_tag="RHX21_004360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase family protein"
                     /protein_id="HDV1989453.1"
                     /translation="RGHQRVLFVVMQADKTEPCHEWDMAGIQPSPAEAQNIREKTEAV
                     FRLFRPVHRVVAVSARTGWELDTLVSALMTALPDHAASPLMTRLQDELRTESVRSQAR
                     EQFTGAVDRIFDTAESVCIASVARTVLRAVRDSVVSVARAVWNWIFF"
     gene            668..3064
                     /locus_tag="RHX21_004361"
     CDS             668..3064
                     /locus_tag="RHX21_004361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dynamin family protein"
                     /protein_id="HDV1989454.1"
                     /translation="MHEKNIALLCDEADRLLQLNINLLRQMVEEPDVLSDSKNENRLL
                     FDKQKALKRIEELEGEQIKTARREMVLAVVGTMKAGKSTTINAIVGQEILPNRNRPMT
                     SVPTLIRHVPGKTEPVLHLEHIQPVRNLLITLQEKLATPAGQQVAQTLQQTGDTRELL
                     DILTDDGWLKNEYHGEEEIFTGLASLNDLVRLAAAMGTEFPFDEYAEVQKLPVIDVEF
                     SHLVGMDACQGTLTLLDTPGPNEAGQPQMEVMMRDQLQKASAVLAVMDYTQMNSKADE
                     DVRKELNAIADVSAGRLFVLVNKFDEKDRNGDGADAVRQKVPAMLNSDVLPASRVYPG
                     SSRQAYLANRALHELRKNGTLPVDEAWVDDFIRGAFGCMKKEYVCKDSELATEGATDL
                     WEGSLIDQLITEVIQSSHSRAAALAVDSAAAKLMQNAENISEYLLLRHQGLQQSIQSL
                     QSHITSLLADIREIADCQEQMTTDVRMAMEEIDTKTRELLTGVCTSLEEELNDYFRSG
                     KRKEQQMLEEEDAEQRRSQSGLWGKISQWSGINNQGREDYRKRDFAPDSPEIKFSDRR
                     EALELMTQIESTVTSLHREAEAQFRPELEKIVSGIETGFRGTALYATENIAGRINARL
                     EDVGFTVKISFPAVSQLQTRLAVKINLSALMEERTETVTRRRRQSGVWGTVCRWFGTS
                     DLGWENYDEDVSRSVININKVREEVMSLTRAYFGELQASIEQDINQPVRQEIDAFFCA
                     FREKVEQLRNTLIQSSEDHKRDQQAQERLTGRLQALNERVPELITDSKALREELETML
                     "
     gene            3061..3966
                     /locus_tag="RHX21_004362"
     CDS             3061..3966
                     /locus_tag="RHX21_004362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HDV1989455.1"
                     /translation="MTSPFIQQIADNRVCQVLTCLPEKFVVDFANGIDVAQEHIRTAG
                     ERTFFRRLKEGLTGEGAARQNAINASLAQGVEASLRWLTEMTTSLATTNYAITRVNDR
                     VSSLVSDTARLAHYSADTREQLLTLADQVHHKLNHLEEKLHRVDQVQRAQLHLEQIFS
                     WWSAGRYASFSPAGRCYVALEELRWGAFGDVIRQSETGQVNQLLDILRHKALTQMAQE
                     SGGSATVRLNTLDWLGGQGREQADNEWHDAINWLGDWCSEEQHPVIWSTTQAAEHLPV
                     RMPRLCSAERLSESMVDEIFQKGAA"
     gene            3963..5033
                     /locus_tag="RHX21_004363"
     CDS             3963..5033
                     /locus_tag="RHX21_004363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDV1989456.1"
                     /translation="MSTEMKTGLVLSGGGAVGAYQAGVVKALAECGTQISMVSGASIG
                     AFNGAIIAASPDLSEAAVRLEALWDHLGNNQVLSVNRLVYFSLLKKLFQAMNLCQIPG
                     RAGALLTTLLRHISTINGFDNLMAQPLLSDEPLTALMDHYLDTDALADGLPLYVSLYP
                     TEGGMQDIIDCIRAELGVGTTKNAVFQHIQSLPRGQQKEALLASAALPLLFRPREVQG
                     TMFGDGGMGGWRNMQGNTPVTPLVDAGCNMVIVTHLSEGSLWDRQAFPDTTILEIRPR
                     KRLKYAGDGGNSGGLLSFTSAHTDAWRQQGYEDTMLAMEHIRKPLAARQALTRSEAVL
                     QKSLDITEEADLALRNAMARIK"
     gene            5169..5852
                     /locus_tag="RHX21_004364"
     CDS             5169..5852
                     /locus_tag="RHX21_004364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989457.1"
                     /translation="MKLPVKLLMSLISLVSVIARAGEYKNYSRDEIKYWRYTSYKGGK
                     LPEGFTDEKFSSAIYNGRIFTMKRLHTLMLFLAVLFTGFNFNAEAATVKQALSCNPEA
                     WAEQPGACPSTYELYEGDATYKAAIDKALKPVGLSGMFGKGGYMDGPGGGITPVNING
                     TVWFQGDGCKANTCGWDFIVTLYNPKTHEVVGYRYFGLDDPAYLVWFGEIGVHEFAYL
                     VKNYVAAVN"
     gene            5868..6278
                     /locus_tag="RHX21_004365"
     CDS             5868..6278
                     /locus_tag="RHX21_004365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989458.1"
                     /translation="MKTFIKTLLVAVTILFSVFATAKQVKLPNNIKYVNTTEAFSCTE
                     IDGMNCQTKNQFNYKDNSYVFVLERGGAWCYDYTVSVVNLKTGKAQMIEYGDNKLCSG
                     SNKPFFEIKNGVPTVGVIDTSGKPVVVAQDKLKI"
     gene            6499..7320
                     /locus_tag="RHX21_004366"
     CDS             6499..7320
                     /locus_tag="RHX21_004366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HDV1989459.1"
                     /translation="MRLASRFGYAANQIRRDRPLTHEELMHYVPSIFGEDRHTSRSER
                     YAYIPTITVLESLQREGFQPFFACQTRVRDPGRRGYTKHMLRLRRAGEINGEHVPEII
                     LLNSHDGTSSYQMLPGYFRFVCQNGCVCGQSLGEVRVPHRGNVVEKVIEGAYEVVGVF
                     DRIEEKRDAMQSLVLPPPARQALAQAALTYRYGDEHQPVTTADILTPRRREDYGKDLW
                     SAYQTIQENMLKGGISGRSAKGKRIHTRAIHSIDTDIKLNRALWVMAETMLESLR"
     gene            7402..>7786
                     /locus_tag="RHX21_004367"
     CDS             7402..>7786
                     /locus_tag="RHX21_004367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HDV1989460.1"
                     /translation="MKTVSQNTPTIYSATTPENNPPQLVASLVPDEQRISFWPQHFGL
                     IPQWVTLEPRVFGWMDRLCEDYCGGIWNLYTLNNGGAFMAPEPDDDDDETWVLFNAMN
                     GNRAEMSPEAAGIAACLMTYSHHACR"
BASE COUNT         1999 a         1906 c         2126 g         1755 t
ORIGIN      
        1 cggggacatc agcgggtact gtttgtggtg atgcaggccg ataaaacgga gccctgccat
       61 gaatgggata tggccggtat tcagccttct cccgcagagg cacagaacat tcgcgaaaaa
      121 acggaggcgg tattccgtct gttccggccc gtacatcggg ttgttgccgt atcggcccgc
      181 accggctggg aactggatac gctggtcagt gcgctcatga cagcacttcc cgaccatgcc
      241 gccagtcccc tgatgacccg cctgcaggac gagctgcgca cggagtctgt ccggtctcag
      301 gcccgtgaac agtttaccgg tgcggtggac cggatatttg acacggcgga gagcgtctgc
      361 attgcctctg ttgcacgcac ggttctgcgc gccgtccgtg actcggtggt ctctgttgcc
      421 cgcgcggtat ggaactggat tttcttctga acccggtggt gatgtaccag gctgttgtta
      481 cagattttta actccatgaa aacactatgc aaacgcagcc atacccgggt tgtccccttg
      541 cgttgtgttt ctcaagttaa tagaatacat cgatcgttac tatcatatcg atcgttataa
      601 gcgatcattt gtagtaaatg acctcctccg tggttgtcat gaaaatgcgt cttaggaagg
      661 ttaaataatg cacgaaaaga acatcgccct gctttgtgat gaagccgacc gacttttgca
      721 actgaacatt aatctgctcc ggcaaatggt tgaggagcca gatgtgttat ctgacagtaa
      781 gaacgaaaac agactgcttt ttgataaaca gaaagcactg aaaagaattg aggagctgga
      841 gggcgaacaa atcaaaaccg cccgcaggga gatggtgctg gctgttgtcg gcacgatgaa
      901 agcaggcaaa tcaaccacca tcaacgccat tgtggggcag gaaattctgc ctaaccgtaa
      961 ccgccccatg acctctgtac cgacgctcat ccgccacgtt cccggaaaaa ctgagccggt
     1021 tctccatctg gaacatattc agcctgtccg caatttatta atcacactgc aggaaaaact
     1081 cgccaccccg gcaggacagc aggtcgcaca gaccctgcag caaaccgggg atacccgcga
     1141 actgctggat attctgacgg atgatggctg gctcaaaaat gaataccacg gggaggagga
     1201 aatctttacc ggactggcat cgttaaacga tctggttcgt cttgctgcgg caatggggac
     1261 tgaatttcct tttgatgaat acgcagaagt gcagaaactg ccggtgatcg acgtggaatt
     1321 cagccatctg gtggggatgg atgcatgcca gggaacactc acactgctgg atacccccgg
     1381 ccctaatgag gccggacaac cgcagatgga agtgatgatg cgggatcaac tgcagaaagc
     1441 ctctgcggtt ctggctgtga tggattacac ccagatgaac tcaaaagcgg atgaagacgt
     1501 ccgtaaagag cttaatgcca ttgctgacgt atcagccggc cgcctgtttg tactggtcaa
     1561 taaatttgat gagaaagacc gcaatggcga tggggcagat gccgtacgcc agaaagttcc
     1621 ggcaatgctg aacagcgatg tgctgcccgc ctcccgcgtt tatcccggat cctcacgcca
     1681 ggcatacctg gctaaccgtg cgcttcatga gttacggaaa aacggaaccc ttcctgttga
     1741 tgaagcctgg gtcgatgatt ttatcagagg tgccttcggt tgcatgaaaa aagaatacgt
     1801 ctgtaaagac agtgaactgg caactgaagg ggcgacagac ctgtgggaag gctcacttat
     1861 cgatcaactg ataacggaag tcatacagag ctcacattcc agagctgcgg cactggcggt
     1921 tgactctgcc gccgcaaaac tgatgcagaa tgcagaaaat atcagtgaat acctgttgtt
     1981 acgccatcag gggctacagc aaagcattca gtcactgcag tcgcatatca ccagcctgct
     2041 tgcggatatc cgggaaatcg cggactgtca ggagcagatg accactgatg tcagaatggc
     2101 catggaggag atcgatacta aaacccggga attactgacg ggggtctgca cctcactgga
     2161 agaggagctg aatgactatt tcagaagcgg taaacgcaaa gaacagcaaa tgctggagga
     2221 agaagacgca gaacaacgaa ggtctcagtc cggattatgg gggaaaattt ctcaatggtc
     2281 cggtatcaac aaccagggcc gggaggatta caggaaacga gattttgccc cggacagccc
     2341 cgaaataaaa ttcagtgatc gcagggaagc ccttgaactg atgacgcaaa tcgaatcgac
     2401 cgtgaccagc ctgcaccgtg aggctgaagc acagttccgg cctgagctgg agaaaatcgt
     2461 cagcgggatt gaaacaggtt ttcgtggcac ggccctgtac gccacagaaa acattgccgg
     2521 tcgcatcaat gcccgcctgg aggatgtggg ctttaccgta aaaatcagtt ttccggcagt
     2581 cagccagtta cagacccggc tcgcggtaaa aataaatctg agtgcgctta tggaggaaag
     2641 aacggagacc gtcacccgtc gccgtcggca gagtggcgta tggggaaccg tttgtcgatg
     2701 gtttggcacc agtgacctgg gctgggaaaa ctatgacgag gatgtgagtc gcagcgtgat
     2761 caatatcaac aaggtcagag aggaagttat gtcactgacc cgggcatatt tcggggagct
     2821 gcaggcatcc attgagcagg atattaacca gcccgtccgc caggaaatcg atgccttttt
     2881 ctgcgcattc agggagaaag ttgaacaact gcgtaacacg ctgattcaga gctctgaaga
     2941 tcataaacgc gatcagcagg cgcaggaacg gcttaccggg cgacttcagg cattaaatga
     3001 aagggttcct gagctcatta ctgacagtaa ggcgctgagg gaagagctgg agacaatgct
     3061 gtgacttcac catttattca acaaattgct gataaccggg tatgtcaggt actcacctgt
     3121 cttcctgaaa aatttgtggt tgatttcgca aacggaatcg atgttgcaca ggagcatatc
     3181 cgcacggccg gagagcgcac gttcttccgg cgtttaaaag aggggctgac cggcgaaggc
     3241 gctgcacggc agaatgccat caatgcgtcg cttgcacagg gcgttgaggc gtccctgcgc
     3301 tggctgacgg agatgacaac gtcacttgcc accacaaact acgcaattac ccgggtaaac
     3361 gacagggtca gttcactggt cagtgataca gccaggctgg cgcattattc ggctgacacg
     3421 cgggagcagt tactcaccct ggccgatcag gttcaccata aactgaatca tcttgaagaa
     3481 aaactccacc gtgttgacca ggttcagcgg gcgcagttac atcttgagca gatattctca
     3541 tggtggagcg ccgggcgata tgcgtcattt tcccctgccg gacgttgtta tgtggcactt
     3601 gaagagcttc gctggggcgc gtttggtgat gtgatacgtc agagcgaaac aggccaggtt
     3661 aaccagctac tggatattct cagacataaa gcattaacgc agatggcaca ggagagtggc
     3721 ggtagtgcaa ccgtgcgtct gaacactctg gactggcttg gtggtcaggg ccgggagcag
     3781 gcagataacg agtggcatga cgcgattaac tggctgggag actggtgcag tgaagagcag
     3841 catccggtga tctggtcaac cacgcaggct gcagaacact taccggttcg catgcctcgc
     3901 ctctgctctg cagaacgcct ctctgaaagt atggtcgatg aaatatttca gaagggggct
     3961 gcatgagtac agaaatgaaa acggggctgg tgctgtccgg tggcggggcg gtgggcgctt
     4021 atcaggcggg agtggttaag gcactggcag agtgtggtac acagatcagc atggtttcag
     4081 gggccagcat tggcgcattc aatggtgcca ttatcgcggc ctctcccgat ctgtcagaag
     4141 ctgccgtacg cctggaggcg ctctgggatc atctggggaa taatcaggtg ctgtcggtaa
     4201 acagattggt ttacttttca ttgctgaaaa aattgttcca ggcaatgaac ctctgccaga
     4261 tccccggacg tgcaggagca ctgcttacga cgcttcttcg ccatatatcg acaatcaacg
     4321 ggtttgacaa tctgatggct cagccgttgt tgtcagatga gcccctgaca gcgctgatgg
     4381 atcattatct tgatactgat gctctggcag acgggctacc gctgtatgtg tcgctgtacc
     4441 ccacagaagg gggcatgcag gatattattg actgcattcg tgctgaactg ggtgtcggaa
     4501 ccacgaaaaa cgccgttttt cagcatatcc agagcctgcc ccgcggacag cagaaagagg
     4561 ctctgcttgc gtcagccgcg ctgcccctgc tgttccgtcc ccgtgaggtt caggggacaa
     4621 tgttcggtga tggtggtatg ggaggatggc gaaatatgca gggaaatacc cctgtgacgc
     4681 ctctggtcga tgccggatgc aatatggtga ttgtgacgca tctgagtgag ggttctttat
     4741 gggatcgcca ggcttttccg gacaccacaa tccttgagat ccgtccccgg aaaaggctga
     4801 aatatgcagg tgatggtggc aacagcggcg gtctgctcag ttttacatcg gcacataccg
     4861 acgcctggcg tcagcagggc tatgaagaca cgatgctggc gatggagcat atccggaaac
     4921 cgctggcagc acgtcaggca ctgacccggt cagaggcggt attgcagaaa agcctggata
     4981 taacggaaga ggcagatttg gcactgagaa acgcgatggc ccggattaaa taaagacgcc
     5041 ccaaagaaac gccaccgcct gtggtggtgt ttttcctgtc tggtgttatt gaaaatattt
     5101 tcatatatat attacctgag agaaagtttt acccctcacc tgtcaattca ctcactggaa
     5161 atttaattat gaaattacct gtaaagttat taatgagcct tatatctctg gtcagcgtta
     5221 ttgcacgtgc cggggaatat aaaaattaca gccgggatga aataaaatac tggcgatata
     5281 catcatacaa gggggggaaa cttccggaag gtttcactga tgagaaattt tccagcgcca
     5341 tttacaacgg aagaatattt acaatgaaac gtttacatac ccttatgtta tttctggcgg
     5401 ttctgttcac gggctttaac tttaacgcag aagcggctac cgtaaaacaa gctcttagtt
     5461 gtaacccgga agcctgggct gaacaacctg gagcgtgtcc atcaacgtac gagttgtacg
     5521 aaggtgacgc tacctacaaa gccgctatcg acaaagcatt aaaaccggtc ggactgagcg
     5581 gcatgttcgg taaaggcggc tatatggatg gccctggtgg aggtatcacg ccagtaaaca
     5641 ttaacggtac agtctggttc cagggcgacg gttgcaaagc caatacctgc ggctgggact
     5701 ttatcgtaac actctataac ccaaaaaccc atgaagttgt tggctaccgt tactttggtt
     5761 tagatgaccc ggcctacctg gtttggttcg gtgaaattgg cgtgcatgaa ttcgcgtatc
     5821 tggtgaaaaa ctacgtagct gcggttaact aatttaagga gtctatcatg aaaactttta
     5881 tcaaaacttt actcgttgct gtaactattc tgttctctgt cttcgctact gcgaaacaag
     5941 taaaactgcc aaataacatc aaatacgtta atactacaga agcgttttcc tgtaccgaaa
     6001 ttgacggtat gaattgccag acaaagaatc agttcaacta taaagataac agctatgttt
     6061 tcgtgcttga acgtggtggt gcctggtgct acgactacac tgtctcggta gttaacctga
     6121 aaaccgggaa agcacaaatg attgaatacg gggacaataa actgtgctca ggtagcaaca
     6181 aaccgttctt cgaaatcaaa aatggcgtac cgacggtagg agtcatcgac acatccggaa
     6241 aacctgtcgt tgtagcccag gacaaactta aaatctaagg agtaaaccat gcgtttctct
     6301 gcacattatt aatatcaaag gtaaatacag ccccagccat tgttaccgga aagccgctta
     6361 atgcgtggct cgccagtgaa aggcctctca gacaataaac cttattcatt tcacccgtca
     6421 ggccgcgtct tctccgggag acgcggcttt tttcatttat tgcaccagta aatcttaacc
     6481 accgataagg agcaaagtat gcgattagca agtcgttttg gttatgctgc aaaccagata
     6541 cgccgtgacc gcccgctgac acatgaagaa ctgatgcact atgtgcccag tatttttggg
     6601 gaagaccggc atacctcccg cagtgaacgc tatgcgtaca ttcccaccat caccgtacta
     6661 gaaagcctgc agcgggaggg ctttcagccc ttcttcgcct gccagacccg tgtgcgcgac
     6721 ccgggccgcc ggggatacac aaaacacatg ctgcgtctgc ggcgggccgg agagataaac
     6781 ggagaacatg tccctgaaat tattctgctc aactctcatg acggtacctc cagctaccag
     6841 atgctgccgg gttacttcag gttcgtctgc cagaacgggt gcgtctgtgg ccagtctctg
     6901 ggggaagtgc gtgttccaca ccggggaaat gtagtggaga aagttatcga aggggcttac
     6961 gaggtggtgg gcgtgtttga ccggatagag gagaagcgtg atgccatgca gtcgctggtc
     7021 ctgccgccac cggcacgcca ggcgctggca caggcggcac tgacttaccg ttatggtgac
     7081 gaacatcagc ccgtcaccac cgccgacatt ctgacgccgc gacgccggga ggattacggt
     7141 aaggacctgt ggagcgcata tcagaccatc caggagaata tgctgaaagg cgggatttcc
     7201 ggtcgcagtg caaaaggaaa acgtatccat acccgggcca ttcacagcat tgataccgac
     7261 attaagctca atcgcgcatt gtgggtgatg gcagaaacga tgctggagag cctgcgctga
     7321 tgccgtttcc ctgagtgagg gaatcattca gctttcgttc ctgaaaaaca cacatttatt
     7381 tgttatttaa ggagttatct catgaaaacc gtttctcaga atacccccac aatttattca
     7441 gctacaacac cagagaataa tccgcctcag ttggttgcca gcctcgtccc tgatgaacag
     7501 cgcatcagct tctggccgca gcattttggc ctcattccac agtgggtgac cctggagccc
     7561 cgtgtcttcg gctggatgga ccgtctgtgc gaagactact gcggtggtat ctggaatctg
     7621 tacaccctga acaacggcgg ggcatttatg gcacccgaac cggatgacga tgatgacgaa
     7681 acatgggtac tgttcaatgc catgaacggt aaccgcgcag aaatgagccc ggaagccgcc
     7741 ggtattgccg cctgtctgat gacgtacagt catcatgcct gtcgta
//
LOCUS       DAPGUL010000176         7741 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.179, whole genome shotgun sequence.
ACCESSION   DAPGUL010000176 DAPGUL010000000
VERSION     DAPGUL010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7741
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.179"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            170..388
                     /locus_tag="RHX21_004368"
     CDS             170..388
                     /locus_tag="RHX21_004368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312842.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HDV1989461.1"
                     /translation="MAMNTVFLHLSEEAIKRLNKLRGWRKVSRSAILREAVEQYLERQ
                     QFPVRKAKGGRQKGEVVGVDDQCKEHKE"
     gene            606..848
                     /locus_tag="RHX21_004369"
     CDS             606..848
                     /locus_tag="RHX21_004369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709694.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989462.1"
                     /translation="MNSLAGIDMGRILLDLSNEVIKQLDDLEVQRNLPRADLLREAVD
                     QYLINQSQTARTSVPGIWQGCEEDGVEYQRKLREEW"
     gene            complement(1178..2107)
                     /gene="fdhE"
                     /locus_tag="RHX21_004370"
     CDS             complement(1178..2107)
                     /gene="fdhE"
                     /locus_tag="RHX21_004370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory protein FdhE"
                     /protein_id="HDV1989463.1"
                     /translation="MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNLYNRRAERLREL
                     AENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTARIKEASAQGKPPLDIHVLPRDKH
                     WQKLLMALIAELKPEMSGPALAVIENLEKASTQELEDMASALFASDFSSVSSDKAPFI
                     WAALSLYWAQMANLIPGKARAEYGEQRQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLC
                     ETEWHVVRVKCSNCEQSGKLHYWSLDDEQAAIKAESCDDCGTYLKILYQEKDPKIEAV
                     ADDLASLVLDARMEQEGYARSSINPFLFPGEGE"
     gene            complement(2104..2739)
                     /gene="fdoI"
                     /locus_tag="RHX21_004371"
     CDS             complement(2104..2739)
                     /gene="fdoI"
                     /locus_tag="RHX21_004371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase cytochrome b556 subunit"
                     /protein_id="HDV1989464.1"
                     /translation="MKRRDTIVRYTAPERINHWITAFCFILAAVSGLGFLFPSFNWLM
                     QIMGTPQLARILHPFVGVVMFASFIIMFFRYWHHNLINRDDIFWAKNIRKIVVNEEVG
                     DTGRYNFGQKCVFWAAIIFLVLLLVSGVIIWRPYFAPAFSIPVIRFALMLHSFAAVAL
                     IVVIMVHIYAALWVKGTITAMVEGWVTSAWAKKHHPRWYREVRKTTEKKAE"
     gene            complement(2736..3638)
                     /gene="fdoH"
                     /locus_tag="RHX21_004372"
     CDS             complement(2736..3638)
                     /gene="fdoH"
                     /locus_tag="RHX21_004372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase O subunit beta"
                     /protein_id="HDV1989465.1"
                     /translation="MAYQSQDIIRRSATNGLTPAPQARDFQEEVAKLIDVTTCIGCKA
                     CQVACSEWNDIRDTVGNNIGVYDNPNDLSAKSWTVMRFSEVEQNDKLEWLIRKDGCMH
                     CSDPGCLKACPAEGAIIQYANGIVDFQSEQCIGCGYCIAGCPFDIPRLNPEDNRVYKC
                     TLCVDRVVVGQEPACVKTCPTGAIHFGTKESMKTLASERVAELKTRGYDNAGLYDPAG
                     VGGTHVMYVLHHADKPNLYHGLPENPEISETVKFWKGIWKPLAAVGFAATFAASIFHY
                     VGVGPNRADEEENNLHEEKDEERK"
     gene            complement(3651..6701)
                     /gene="fdnG"
                     /locus_tag="RHX21_004373"
     CDS             complement(3651..6701)
                     /gene="fdnG"
                     /locus_tag="RHX21_004373"
                     /EC_number="1.17.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(6114..6116),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit alpha"
                     /protein_id="HDV1989466.1"
                     /translation="MQVSRRQFFKICAGGMAGTTAAALGFAPSVALAETRQYKLLRTR
                     ETRNTCTYCSVGCGLLMYSLGDGAKNAKASIFHIEGDPDHPVNRGALCPKGAGLVDFI
                     HSESRLKFPEYRAPGSDKWQQISWEEAFDRIAKLMKEDRDANYIAQNAEGVTVNRWLS
                     TGMLCASASSNETGYLTQKFSRALGMLAVDNQARVUHGPTVASLAPTFGRGAMTNHWV
                     DIKNANLVVVMGGNAAEAHPVGFRWAMEAKIHNGAKLIVIDPRFTRTAAVADYYAPIR
                     SGTDIAFLSGVLLYLLNNEKFNREYTEAYTNASLIVREDYGFEDGLFTGYDAEKRKYD
                     KSSWTYELDENGFAKRDTTLQHPRCVWNLLKQHVSRYTPDVVENICGTPKDAFLKVCE
                     YIAETSAHDKTASFLYALGWTQHSVGAQNIRTMAMIQLLLGNMGMAGGGVNALRGHSN
                     IQGLTDLGLLSQSLPGYMTLPSEKQTDLQTYLTANTPKPLLEGQVNYWGNYPKFFVSM
                     MKAFFGDKATAENSWGFDWLPKWDKGYDVLQYFEMMKEGKVNGYICQGFNPVASFPNK
                     NKVIGCLSKLKFLVTIDPLNTETSNFWQNHGELNEVDSSKIQTEVFRLPSTCFAEENG
                     SIVNSGRWLQWHWKGADAPGIALTDGEILSGIFLRLRKMYAEQGGANPDQVLNMTWNY
                     AIPHEPSSEEVAMESNGKALADITDPATGAVIVKKGQQLSSFAQLRDDGTTSCGCWIF
                     AGSWTPEGNQMARRDNADPSGLGNTLGWAWAWPLNRRILYNRASADPQGNPWDPKRQL
                     LKWDGTKWTGWDIPDYSAAPPGSGVGPFIMQQEGMGRLFALDKMAEGPFPEHYEPFET
                     PLGTNPLHPNVISNPAARIFKDDAEALGKADKFPYVGTTYRLTEHFHYWTKHALLNAI
                     LQPEQFVEIGESLANKLGIAQGDTVKVSSNRGYIKAKAVVTKRIRTLKANGKDIDTIG
                     IPIHWGYEGVAKKGFIANTLTPFVGDANTQTPEFKSFLVNVEKV"
     gene            6895..7728
                     /gene="fdhD"
                     /locus_tag="RHX21_004374"
     CDS             6895..7728
                     /gene="fdhD"
                     /locus_tag="RHX21_004374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HDV1989467.1"
                     /translation="MKKTQRKEIENVTNITGVRQIELWRRDDLQHPRLDEVAEEVPVA
                     LVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSS
                     RRFMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDF
                     QPVGQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSS
                     RASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLS
                     N"
BASE COUNT         1783 a         1999 c         2065 g         1894 t
ORIGIN      
        1 ataactaaac catttttgag taataaatga aacaactgca acactcttat tatttctgga
       61 aaacgcctcg caaaaacaaa acaacatgca aaaatccgct ttttttaaat gattttccgg
      121 cgtaattttc gcacatacat taatgagtaa tatatgtaag gtattggtaa tggcgatgaa
      181 tacggttttt cttcatttat cagaagaggc aattaaacgg ctgaacaagc ttcggggctg
      241 gcgtaaggtt tcacgatctg caattttacg cgaagcggta gagcaatatc tggaacgtca
      301 gcaattcccg gtgcgtaaag caaagggagg caggcaaaag ggggaggtag ttggtgttga
      361 tgatcagtgt aaggagcata aggaatgaca aaaatttttc attcttgaat ataaaaaaca
      421 gatgccctta ttctggtatt aatacaaggc tgttttactt gaacttataa taactgcaac
      481 tgttacatca tatctggaaa acgcctcgca aaaataaaaa atgatgcgta aatgagcttt
      541 ctttaaagat tcggcaaggg tacttttctc tccatagatt caaaaatgat attggcgaga
      601 tatttatgaa ctctctggca ggtatagata tgggcagaat tttactcgat ttatcgaatg
      661 aggtgattaa gcaacttgat gatctcgagg tgcagcgtaa tcttcctcgt gcggacctat
      721 taagggaagc ggtagatcaa tacctgataa atcaatcgca aacagcaaga accagtgttc
      781 ctggcatctg gcaagggtgt gaggaagatg gtgtcgaata tcagcgtaag ctgcgcgagg
      841 aatggtaatg ggaaaaaatg atgtcaatca gattgctgac aacgtgcgcg ttgttcatgc
      901 cggatgcggc gtgaacgcct tatccggcct acaaagtcgt ataaattcaa tgtattgcag
      961 tttattggta ggcctgataa gcgcagcgca tcaggcaatc ttacgcttgt catcagtctc
     1021 atgcccataa ccttattgat gtggtggtgg gtaaattgag gccaaaccgg cactggcggc
     1081 atagcttgag gtggtaacgc ggaatacgag agatggtgtc gtcacaccct atgagctgta
     1141 atccgggcga cctgcgccac ccggaaaacg tcagagatta ctctccttca cccggaaaca
     1201 ggaacgggtt gatggaactg cgggcatagc cttcttgctc cattcgtgcg tccagtacca
     1261 gagaggcgag gtcatctgct acggcttcga tttttggatc tttttcctga tagagaattt
     1321 tcaggtaagt gccgcagtca tcgcagcttt cggctttaat cgcggcctgt tcgtcatcca
     1381 gcgaccagta atgcagtttg ccgctctgct cgcagttgct gcattttacg cgcactacgt
     1441 gccattcagt ttcacacagg ttgcagtgca ggtaacgtag cccctgagtg gtgccaattt
     1501 gcaccatgct ggacaccggc atagaaccac aaaccgggca atattgacgt tgctcgccgt
     1561 attcagcgcg ggctttgccg gggatcagat tggccatctg cgcccagtag agcgacagtg
     1621 cagcccagat aaacggcgct ttatcgctgc tgacggacga gaaatcagag gcaaacagcg
     1681 cgctggccat atcttccagc tcctgagtcg atgccttctc cagattctca atcactgcca
     1741 gcgccgggcc gctcatttca ggtttcagct cagcaatcag cgccatcagc agcttttgcc
     1801 agtgcttatc acgcggcaga acgtgaatat ccagcggggg cttgccttgt gcgctggctt
     1861 ctttaatgcg cgcagtcaga tccatctcca gcggatggtc gtacagcacc acttcctggg
     1921 cgtgggcgat aagcgcagca aagcgcaggt aatcacccag aggattattt tctgccagct
     1981 cgcgcagacg ctcggcgcgg cggttgtata aattcttgag ccgagggaac aataacggcg
     2041 gaatcatatc cgccgtacgt ttctcgcttg aacccagctc atcttgcggg attatgcgaa
     2101 tactcattca gctttctttt ccgttgtctt gcggacctca cggtaccagc gcgggtgatg
     2161 tttcttcgcc caggcgctgg taacccatcc ttccaccatg gcggtaatcg tgcctttcac
     2221 ccaaagggcg gcgtagatat gcaccatgat aaccacaatt aacgccactg cggcaaatga
     2281 atgcagcatt aacgcgaatc ggatcaccgg gattgagaaa gcaggcgcaa aataaggacg
     2341 ccagataatc acgccgctca ccagcagcag aaccaggaaa ataatcgccg cccagaaaac
     2401 gcatttctga ccgaagttat aacgcccggt gtcacctact tcctcgttga cgacgatctt
     2461 acgaatattc ttcgcccaaa agatatcatc ccgattgatt aggttgtgat gccagtaacg
     2521 gaaaaacatg atgatgaacg aggcaaacat aaccacgccg acaaacgggt gcagaattcg
     2581 cgccagctgc ggtgtgccca tgatttgcat caaccagttg aaggacggga acaaaaagcc
     2641 cagcccgctc accgccgcca ggatgaagca gaaggcggtg atccagtggt tgatacgttc
     2701 cggcgcggtg tagcgcacga tggtgtcacg tcgtttcatt tgcgctcctc gtctttctct
     2761 tcgtgcagat tattctcttc ctcatccgca cggttcggac cgacacccac gtagtggaag
     2821 atactggccg caaaggtagc cgcaaagcca acagccgcga gcggtttcca gatgcctttc
     2881 cagaatttca cggtttcgct gatttccggg ttctccggca agccatgata cagatttggc
     2941 ttgtcagcat ggtgcagcac gtacatgacg tgtgtaccac cgacgcctgc cggatcgtac
     3001 agacccgcat tgtcgtaacc gcgggttttc agctcagcaa cgcgctcgct cgccagcgtt
     3061 ttcatcgact ctttcgtacc gaagtgaatc gcgcccgttg ggcaggtctt cacgcaggct
     3121 ggttcttgcc caaccaccac gcggtcaacg cacagcgtac atttgtagac gcggttgtct
     3181 tccgggttga ggcgcggaat gtcgaacgga cagcccgcaa tgcaataacc gcagccaatg
     3241 cactgctcgg actggaagtc gacgataccg ttggcatact gaataattgc accttccgcc
     3301 gggcacgctt tcaggcagcc tggatcggaa cagtgcatac agccgtcttt gcggatcagc
     3361 cattccagtt tgtcgttctg ctccacttcc gagaagcgca ttaccgtcca cgatttggcg
     3421 cttaaatcat tggggttgtc gtacacccca atgttattgc cgacggtatc gcgaatgtcg
     3481 ttccactctg aacacgccac ctgacaggct ttacagccga tacaggtggt aacgtcgatg
     3541 agtttcgcca cttcttcctg gaagtcccgc gcctgaggcg cgggggtcag accgttagtc
     3601 gcggaacgac gaatgatatc ttgagattga taagccatat gtcgtctccg ttacaccttt
     3661 tccacattca caaggaagga cttaaactcc ggcgtctgcg tgttcgcatc accaacgaat
     3721 ggcgttaaag tattggcaat aaagcctttt ttagctacgc cttcatagcc ccagtgaatc
     3781 ggaataccga tggtatcgat atctttgccg ttcgctttca gcgtgcgaat acgtttggtc
     3841 accaccgctt tggctttgat atagccacgg ttggaggaga ctttcacggt atcgccctgg
     3901 gcaatgccaa gtttattcgc cagcgactcc ccgatttcca caaactgctc tggctgcaaa
     3961 atcgcgttca acagcgcgtg tttggtccag tagtggaagt gctcggtcag acgataggtg
     4021 gttccgacat acgggaactt atcggcttta cccaatgctt cggcgtcgtc tttaaagata
     4081 cgtgcagccg ggttcgagat aacgtttgga tgcagcgggt tagttcccag cggcgtttca
     4141 aacggctcgt agtgttccgg gaacggacct tccgccatct tatcgagggc aaacagacgc
     4201 cccatgcctt cctgctgcat gataaacggc ccgacgccgc tacccggagg cgctgcgctg
     4261 tagtccggaa tatcccagcc ggtccactta gtgccgtccc atttcagcaa ctgacgcttc
     4321 ggatcccacg ggttaccctg cggatctgcg gaggcgcggt tatacagaat gcggcggtta
     4381 agcggccatg cccatgccca gcccagcgtg ttaccgaggc cagacggatc ggcgttatca
     4441 cggcgtgcca tctggttgcc ttccggcgtc cagctaccgg cgaaaatcca gcagccacag
     4501 gaggttgtac cgtcatcgcg caattgggcg aacgaactaa gttgttggcc tttcttgacg
     4561 ataaccgcac cggttgccgg atcggtaata tcggccagcg ccttaccgtt gctctccatc
     4621 gccacttctt ctgaagatgg ctcatgcgga atggcgtagt tccatgtcat gttcagcacc
     4681 tggtccgggt tcgcgccacc ctgttcggca tacatcttgc gcaagcgcag gaagataccg
     4741 gagaggatct cgccgtcagt cagcgcaatc cccggggcgt ccgcaccttt ccagtgccac
     4801 tgtaaccagc gacctgagtt aacgatagaa ccgttctctt ccgcgaagca ggtcgatggc
     4861 agacggaaca cttcggtctg gatcttcgac gagtcaactt cgttcagctc accgtggttc
     4921 tgccagaagt tagaggtttc agtgttcagt gggtcgatgg tgacgaggaa cttcagtttc
     4981 gacagacaac cgatcacttt gtttttgttc gggaatgagg caacagggtt aaagccctgg
     5041 cagatatagc cattgacctt gccctctttc atcatctcga agtattgcag gacgtcgtag
     5101 cctttatccc acttcggcaa ccagtcaaag ccccagctat tttccgccgt cgctttatca
     5161 ccaaagaagg ccttcatcat agagacgaag aatttcgggt agttgcccca gtagtttacc
     5221 tggccttcca gcagcggttt tggcgtgttg gcggtaaggt aggtttgcag atcggtctgc
     5281 ttctcgcttg gcagcgtcat gtaacctggc aggctctgcg acagcagccc caggtccgtc
     5341 agcccctgaa tattggagtg accgcgcagg gcgttaacgc cgccgcctgc catccccata
     5401 ttgccgagca gcagctggat catcgccatc gtacgaatgt tttgcgcacc aacggagtgt
     5461 tgcgtccagc cgagggcata caggaacgag gcagttttat cgtgagcact ggtttctgcg
     5521 atgtattcgc agactttcag gaacgcgtct tttggcgtac cacagatgtt ttcaaccaca
     5581 tctggcgtgt agcgggaaac gtgctgtttc agcaagttcc acacgcagcg cggatgttgc
     5641 agcgtggtat cgcgtttggc gaagccgttt tcgtccagtt cataagtcca ggaggattta
     5701 tcgtacttgc gtttttccgc gtcgtagccg gtgaacaggc catcttcaaa gccgtaatcc
     5761 tcacgcacga tcaggctggc gttggtatag gcttcggtgt attcgcggtt gaatttttca
     5821 ttgttcagca ggtacagcaa tacgcctgac aggaaagcaa tgtcagtacc ggaacgaata
     5881 ggggcatagt agtcagctac cgccgccgta cgcgtaaagc gaggatcgat cacaatcagc
     5941 ttcgcgccgt tgtgaatttt ggcttccatc gcccagcgga acccgaccgg gtgagcttca
     6001 gcggcgttac cgcccatcac cacgacgagg ttggcgttct tgatgtcgac ccagtggttg
     6061 gtcatcgcac cgcgaccaaa tgttggagca agacttgcta ccgttggtcc gtgtcagaca
     6121 cgcgcctggt tgtcgaccgc gagcataccc agcgcgcggg agaatttttg cgttaaatag
     6181 ccggtttcgt tactcgacgc ggaagcacac agcatcccgg tggagagcca gcggttaaca
     6241 gtcacgcctt cggcgttttg cgcaatgtag ttagcatcgc ggtcttcttt catcagtttg
     6301 gcgatgcgat caaacgcctc ttcccaactg atttgctgcc atttatcaga acctggcgca
     6361 cggtattccg gaaacttcag acggctttcg gagtggatga aatccaccag gccagcgcct
     6421 ttcggacaaa gtgcaccgcg gttgaccggg tgatccggat cgccttcgat atggaagata
     6481 gatgctttgg cgttttttgc tccgtcaccg aggctgtaca tcaacagccc acagcctacg
     6541 gaacaatagg tgcaggtatt acgggtttcg cgggtgcgca gcagtttata ctgccgggtt
     6601 tccgcgagtg ctacgctggg tgcaaaaccc agtgccgctg ccgtggtgcc tgccataccg
     6661 ccagcgcaga tcttaaagaa ctgccttctg ctgacctgca tggattgctc cttgtttcga
     6721 cattgtcacg tcccatttac attcgcttgc tgcgtgtgca gggagtggga gttatttttc
     6781 tttgcggaag gggccgcaaa ggtccagaat tggctcaatt tccctccatc caggaagggt
     6841 ttgtaacaga ataccataat gttggtgtgt gtgttcttat ctggttaaga gaaagtgaaa
     6901 aaaacacagc gaaaagaaat cgaaaatgtg acaaatatca caggtgttcg tcaaattgag
     6961 ttatggcggc gtgatgattt acaacaccca cggttagatg aggtcgcgga agaagttccc
     7021 gttgcgctgg tctacaacgg catttcgcat gtggtgatga tggcgtcgcc caaagacctt
     7081 gagtactttg cgctcggttt ttcgctttcc gaggggatta tcgaaagtcc gcgcgatatc
     7141 ttcggcatgg atgtcgttcc ttcctgtaat ggtcttgaag tacaaattga gctttccagc
     7201 cgccgcttta tggggttgaa ggagcgccgc cgggcgctgg cgggacgtac gggctgtggc
     7261 gtatgcggcg tggagcaact taatgacatc ggaaaaccgg tgcagccgct accgttcacc
     7321 cagacgtttg atctcaacaa actggatgat gcattacgtc atctcaacga ttttcagcca
     7381 gtggggcaac tgactggttg tactcacgcc gctgcctgga tgttgccatc tggcgaactg
     7441 gtcggcgggc atgaagacgt gggtcgccat gtggcgctgg acaaactgtt aggccgccgg
     7501 tcacaagaag gggaaagctg gcagcaaggt gcggtactgg tttccagtcg tgccagttat
     7561 gaaatggtgc aaaagtcggc gatgtgcggc gtagagattt tgtttgcggt gtctgccgcg
     7621 accacgcttg ctgtagaagt ggctgagcgc tgtaatctga cactggtagg tttttgtaaa
     7681 ccgggtcggg caacggttta tacccatccg cagcgtttga gcaattaatt aaaataagtc
     7741 c
//
LOCUS       DAPGUL010000177         7575 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.180, whole genome shotgun sequence.
ACCESSION   DAPGUL010000177 DAPGUL010000000
VERSION     DAPGUL010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7575
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.180"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            128..235
                     /locus_tag="RHX21_004375"
     CDS             128..235
                     /locus_tag="RHX21_004375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588455.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989468.1"
                     /translation="MPTKRFDKKHWKMVVVLLAICGAMLLLRWAAMIWG"
     gene            complement(288..1046)
                     /locus_tag="RHX21_004376"
     CDS             complement(288..1046)
                     /locus_tag="RHX21_004376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiY family protein"
                     /protein_id="HDV1989469.1"
                     /translation="MKLLKTVPAIVMLAGGMFASLNAAADDSVFTVMDDPASAKKPFE
                     GNLNAGYLAQSGNTKSSSLTADTTMTWYGQTTAWSLWGNASNTSSNDERSSEKYAAGG
                     RSRFNLTDYDYLFGQASWLTDRYNGYRERDVLTAGYGRQFLNGPVHSFRFEFGPGVRY
                     DKYTDNASETQPLGYASGAYAWQLTDNAKFTQGVSVFGAEDTTLNSESALNVAINEHF
                     GLKVAYNVTWNSEPPESAPEHTDRRTTLSLGYSM"
     gene            1333..2262
                     /gene="pfkB"
                     /locus_tag="RHX21_004377"
     CDS             1333..2262
                     /gene="pfkB"
                     /locus_tag="RHX21_004377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707391.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase II"
                     /protein_id="HDV1989470.1"
                     /translation="MVRIYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINV
                     ARAIAHLGGSATAIFPAGGATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGE
                     QYRFVMPGAALNEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQNQG
                     IRCIIDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKA
                     KRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMV
                     RFGVAAGSAATLNQGTRLCSHDDTQKIYAYLSR"
     gene            2363..2653
                     /gene="ghoS"
                     /locus_tag="RHX21_004378"
     CDS             2363..2653
                     /gene="ghoS"
                     /locus_tag="RHX21_004378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system endoribonuclease
                     antitoxin GhoS"
                     /protein_id="HDV1989471.1"
                     /translation="MASGDLVRYVITVMLHEDTLTEINELNNYLTRDGFLLTMTDDEG
                     NIHELGTNTFGLISTQSEEEIRELVSGLTQSATGKDPEITITTWEEWNSNRK"
     gene            2759..3619
                     /locus_tag="RHX21_004379"
     CDS             2759..3619
                     /locus_tag="RHX21_004379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HDV1989472.1"
                     /translation="MWQAISRLLSEQLGEGEIELRNELPGGEVHAAWHLRYAGHDFFV
                     KCDERELLPGFTAEADQLELLSRSKTVTVPKVWAVGADRDYSFLVMDYLPPRPLDAHS
                     AFILGQQIARLHQWSDQPQFGLDFDNSLSTTPQPNTWQRRWSTFFAEQRIGWQLELAA
                     EKGIAFGNIDAIVEHIQQRLASHQPQPSLLHGDLWSGNCALGPDGPYIFDPACYWGDR
                     ECDLAMLPLHTEQPPQIYDGYQSVSPLPADFLERQPVYQLYTLLNRARLFGGQHLVIA
                     QQSLDRLLAA"
     gene            complement(3660..4196)
                     /locus_tag="RHX21_004380"
     CDS             complement(3660..4196)
                     /locus_tag="RHX21_004380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YniB family protein"
                     /protein_id="HDV1989473.1"
                     /translation="MTYQQAGRIAVLKRILGWVIFIPALISTLISLLKFMNTRQENQE
                     GINAVMLDFTHVMIDMMQANTPFLNLFWYNSPTPNFNGGVNVMFWVIFILIFVGLALQ
                     DSGARMSRQARFLREGVEDQLILEKAKGEEGLTREQIESRIVVPHHTIFLQFFSLYIL
                     PVICIAAGYVFFSLLGFI"
     gene            4343..5011
                     /gene="hxpB"
                     /locus_tag="RHX21_004381"
     CDS             4343..5011
                     /gene="hxpB"
                     /locus_tag="RHX21_004381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexitol phosphatase HxpB"
                     /protein_id="HDV1989474.1"
                     /translation="MSTPRQILAAIFDMDGLLIDSEPLWDRAELDVMASLGVDISRRN
                     ELPDTLGLRIDMVVDLWYARQPWNGPSRQEVVERVIARAISLVEETRPLLPGVREAVA
                     LCKEQGLLVGLASASPLHMLEKVLTMFDLRDSFDALASAEKLPYSKPHPQVYLDCAAK
                     LGVDPLTCVALEDSVNGMIASKAARMRSIVVPAPEAQNDPRFVLANVKLSSLTELTAK
                     DLLG"
     gene            5174..5764
                     /locus_tag="RHX21_004382"
     CDS             5174..5764
                     /locus_tag="RHX21_004382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707386.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDV1989475.1"
                     /translation="MTAEGHLLFSIACAVFAKNAELTPVLAQGDWWHIVPSAILTCLL
                     PDIDHPKSFLGQRLKWISKPIARAFGHRGFTHSLLAVFALLATFYLKVPEGWFIPADA
                     LQGMVLGYLSHILADMLTPAGVPLLWPCRWRFRLPILVPQKGNQLERFICMALFVWSV
                     WMPHSLPENSAVRWSSQMINTLQIQFHRLIKHQVEY"
     gene            5897..7288
                     /gene="tcyP"
                     /locus_tag="RHX21_004383"
     CDS             5897..7288
                     /gene="tcyP"
                     /locus_tag="RHX21_004383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine/sulfocysteine:cation symporter"
                     /protein_id="HDV1989476.1"
                     /translation="MNFPLIANIVVFVVLLFALAQTRHKQWSLAKKVLVGLVMGVVFG
                     LALHTIYGSDSQVLKDSVQWFNIVGNGYVQLLQMIVMPLVFASILSAVARLHNASQLG
                     KISFLTIGTLLFTTLIAALVGVLVTNLFGLTAEGLVQGGAETARLNAIESNYVGKVSD
                     LSVPQLVLSFIPKNPFADLTGANPTSIISVVIFATFLGVAALKLLKDDAPKGERVLAA
                     IDTLQSWVMKLVRLVMQLTPYGVLALMTKVVAGSNLQDIIKLGSFVVASYLGLLIMFA
                     VHGILLGINGVSPLKYFRKVWPVLTFAFTSRSSAASIPLNVEAQTRRLGVPESIASFA
                     ASFGATIGQNGCAGLYPAMLAVMVAPTVGINPLDPMWIATLVGIVTVSSAGVAGVGGG
                     ATFAALIVLPAMGLPVTLVALLISVEPLIDMGRTALNVSGSMTAGTLTSQWLKQTDKA
                     ILDSEDDAELAHR"
     gene            complement(7292..>7575)
                     /locus_tag="RHX21_004384"
     CDS             complement(7292..>7575)
                     /locus_tag="RHX21_004384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416244.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989477.1"
                     /translation="NINLLFNPLNLPGMGSGVLEDIMSIPDSSLRKRLGYEVLSFSLQ
                     AHSLSQECIDKLDIFFADDLFKYESVCIAAMEHLKSKATAPIQNGPLPA"
BASE COUNT         1916 a         1841 c         1866 g         1952 t
ORIGIN      
        1 ataaaacgca gaaacagtga tcaggtgtac aacgccaccc gacggctgta ataacaaaaa
       61 atcccttgat gcctgtccct tttgttacac tccgttatca cgcacaagag atatgcagga
      121 cactggtatg ccgactaaac gctttgataa aaaacactgg aagatggtgg tggtgctact
      181 ggcaatctgt ggcgctatgt tgttgctacg ttgggcagca atgatttggg gctgagcagt
      241 gacaaacgaa gacagccaga ccgcataaca cggtccggca gataatttta catgctgtag
      301 cccagcgata aggttgtccg acgatcggta tgttccggtg cagactctgg aggttcagag
      361 ttccatgtga cgttgtaagc cactttcagt ccaaaatgtt cattaatagc aacatttaat
      421 gcgctttcgg agttcagcgt tgtgtcttcc gcgccaaaga cggaaacacc ctgcgtaaat
      481 ttagcgttgt cagtcaactg ccatgcataa gcaccggagg catagcccag cggctgagtt
      541 tcactggcat tgtcggtata tttgtcgtaa cgcacacctg gaccgaattc aaagcggaaa
      601 ctgtgtaccg ggccattcaa aaactgacga ccataacccg cggtcaacac atcgcgctct
      661 cgatagccgt tataacggtc tgtcagccag cttgcctgac caaataaata gtcataatca
      721 gttaaattaa aacggctacg cccgcccgcc gcatattttt ctgaagaacg ctcatcatta
      781 gaagaagtat tactggcgtt cccccacagc gaccaggcag tggtttgtcc ataccaggtc
      841 atggtggtgt cagccgtaag tgaggagctt ttcgtattgc ctgattgtgc aagatatcct
      901 gcgttcagat taccttcgaa aggtttttta gcgctggcag gatcgtccat gacagtaaaa
      961 acggaatcat cggcagctgc attcagtgac gcaaacatgc cccccgccaa cataacgatg
     1021 gcaggaactg tcttcaaaag cttcatttat caagagtccg tacaacaaaa aaagagacca
     1081 tcgcggtccc ggaaactttc ttaaggatca aagattagcg tccctggaaa ggtaacgaat
     1141 tataaaaagg cgcgaataac ttagcaatgt attcttattt cattttttga ataagcatgt
     1201 ggcgaaaaca gatttttatt tatatatatt tatctgcaaa attttaaata aagctctaat
     1261 aaatcatatt gttaatttct tcactttcgg ctgattcggt gccagactga aatcagccta
     1321 taggaggaaa tgatggtacg tatctatacg ttgacacttg cgccctctct cgatagcgca
     1381 acaattaccc cgcaaattta tcccgaagga aaactgcgct gtaccgcacc ggtgttcgaa
     1441 cccgggggcg gcggcatcaa cgtcgcccgc gccattgccc atcttggagg cagtgccaca
     1501 gcgatcttcc cggcgggtgg cgcgaccggc gaacacctgg tttctctgtt ggcggatgaa
     1561 aatgtccccg tcgctactgt agaagccaaa gactggaccc ggcagaattt acacgtacat
     1621 gtggaagcaa gcggtgagca gtatcgtttt gttatgccag gcgcggcatt aaatgaagat
     1681 gagtttcgcc agcttgaaga gcaagttctg gaaattgaat ccggggccat cctggtcata
     1741 agcggaagcc tgccgccagg tgtgaagctg gaaaaattaa cccaactgat ttccgctgcg
     1801 caaaaccaag ggatccgctg catcatcgac agttctggcg aagcgttaag tgcagcactg
     1861 gcgattggta acatcgagtt ggttaagcct aaccaaaaag aactcagtgc gctggtgaat
     1921 cgcgaactca cccagccaga cgatgtccgc aaagccgcgc aggaaatcgt taatagcggc
     1981 aaggccaaac gggttgtcgt ttcccttggt ccacaaggag cgctgggtgt tgatagtgaa
     2041 aactgcattc aggtggtgcc accaccggtg aaaagccaga gtaccgttgg cgctggtgac
     2101 agcatggtcg gcgcgatgac actgaaactg gcagaaaatg cctctcttga agagatggtc
     2161 cgttttggcg tagctgcggg gagtgcagcc acactcaatc agggaacacg tctgtgctcc
     2221 catgacgata cgcaaaaaat ttacgcttac ctttcccgct aacaaaaaca ttcccccagc
     2281 attgggggaa tcaccaccaa cctgtcggca acgcgtttct ccgactatgc tcaaaagtca
     2341 tgtgataaca aaggggtgaa ctatggccag tggcgatctt gtccgttatg tcataaccgt
     2401 catgttgcat gaggatacat tgactgaaat taacgagttg aataattacc tgactcgcga
     2461 cggttttttg ctcaccatga cggatgatga gggaaatatc catgagctgg ggactaacac
     2521 ttttggactt atcagtaccc aaagtgaaga agaaattaga gaactggttt cggggcttac
     2581 ccaaagtgca accggcaaag atcctgaaat caccatcacg acctgggagg aatggaatag
     2641 caacagaaaa taaatggttt ttgggcaata atcagtctgt ggtgtgcgtt agctcgtgtt
     2701 tttacaccgc attcttgcgc taaccttatg atctggcaga caacatggga gagacatcat
     2761 gtggcaggca atcagtcgtc ttttgagcga gcagttaggt gaaggcgaaa tcgaactgcg
     2821 taatgaactg cctggcggag aagtccatgc cgcatggcat ttgcgctatg caggacatga
     2881 ctttttcgtc aaatgtgatg aaagggaact gcttcccggt tttaccgccg aagccgacca
     2941 actggagtta ctgtcgcgta gtaaaaccgt caccgtgcct aaggtttggg cagtaggcgc
     3001 tgaccgtgac tacagttttc tggtgatgga ttatctccca cctcgtccgc tggatgcgca
     3061 tagcgcattt attcttggtc agcaaattgc gcgtttacat caatggagtg accaaccaca
     3121 atttggcctc gattttgata actcgctctc cacaactcca cagcccaaca cctggcaacg
     3181 tcgctggtca acgttttttg ctgaacaacg gattggctgg cagttggaac tggcagcaga
     3241 gaaagggatc gctttcggca atatcgacgc catcgtcgag catattcagc agcgtctggc
     3301 ctcgcatcaa ccgcagcctt ctctgttgca cggcgattta tggtccggca actgtgcgct
     3361 gggtccggat ggcccgtaca ttttcgaccc tgcctgctac tggggtgacc gagagtgcga
     3421 cctggcgatg ttaccgctgc atactgaaca gccgccacaa atctatgacg gctatcagtc
     3481 agtatccccg ctacctgccg atttccttga acgtcaaccg gtttaccaac tctacacgct
     3541 gttaaatcgt gcaagattat ttggcggtca gcatttggtt attgctcagc agtcattgga
     3601 tagattatta gcagcatgat atgggttgag gataatggcc gctccgtgcg gccttttgat
     3661 taaataaacc caagtagaga aaagaacaca taacctgcag caatacaaat aaccggcagg
     3721 atatatagtg agaaaaactg caggaaaata gtatggtgcg gaacaacaat acgggactca
     3781 atttgttcac gcgttagccc ctcttcccct ttggcttttt ccagaatgag ttgatcttca
     3841 acaccttccc gcaagaagcg cgcctggcga ctcatccggg caccggaatc ctgcaacgcc
     3901 agtccgacaa aaatcaggat gaaaatcacc cagaacataa cgttcacgcc accattaaaa
     3961 ttaggggtcg gggagttata ccagaacaga ttcaaaaaag gcgtattcgc ctgcatcata
     4021 tcgatcatga catgagtaaa gtcgagcatg accgcattaa tgccttcctg gttttcctgc
     4081 cgggtattca taaatttcag caaagaaatc aatgtagaga tcaatgcagg tataaaaatc
     4141 acccaaccca aaatcctttt caaaacagca atgcgtccag cttgttgata cgtcatgagt
     4201 tctccttgat taagacgcgt cgtttcactt agtttacctg tagatatctg ttttcgccca
     4261 ttctttaaag gcgatatgat aggcgcttaa tcataagcac ggcttaatac cttacacata
     4321 atgctctaaa ggagaggttg taatgtcaac cccgcgtcag attcttgctg caatttttga
     4381 tatggatgga ttacttatcg actcagaacc tttatgggat cgagccgaac tggatgtgat
     4441 ggcaagcctg ggggtggata tctcccgtcg taacgagctg ccggacacct taggtttacg
     4501 catcgatatg gtggtcgatc tttggtacgc ccggcaaccg tggaatgggc caagccgtca
     4561 ggaagtagta gaacgggtta ttgcccgtgc catttcactg gttgaagaga cacgtccatt
     4621 attaccaggc gtgcgcgaag ctgttgcgtt atgcaaagaa caaggtttat tggtgggact
     4681 ggcctccgcg tcaccactac atatgctgga aaaagtgttg accatgtttg acttacgcga
     4741 cagtttcgat gccctcgcct cggctgaaaa actgccttac agcaagccgc atccgcaagt
     4801 atatctcgac tgcgcagcaa aactgggcgt tgacccactg acctgcgtgg cgctggaaga
     4861 ctcggtaaat ggcatgatcg cttctaaagc agcccgcatg cgttccatcg tcgttcctgc
     4921 gccagaagcg caaaatgatc cacgttttgt attagcaaac gtcaaactct catcgctgac
     4981 agaactcacc gcaaaagacc ttctcggtta atgaccaggg gcagtgatca cgctgcccct
     5041 ggttctttat ctgaatttgc attcaactga cggattaatc gtcaatttaa gagaaagagt
     5101 tacaccgtca ccacttccgt gcactgtata aaaatcctat actgtacgta tcgacagttt
     5161 agtgagtttt atcatgacgg cggaaggtca ccttctcttt tctattgctt gtgcggtatt
     5221 tgccaaaaat gccgagctga cgcccgtgct ggcacagggt gactggtggc atattgtccc
     5281 ttccgcaatc ctgacgtgtt tgttaccgga catcgatcac ccaaagtcgt ttcttgggca
     5341 gcgattaaaa tggatatcaa aaccgatcgc ccgcgctttt gggcatcgtg gttttaccca
     5401 cagtctgctg gcggtatttg cgctgctggc aaccttttac cttaaggttc cggaaggctg
     5461 gttcattccg gctgatgcgc tacaaggaat ggtgctgggt tatttgagcc acatacttgc
     5521 cgatatgctg acacccgccg gtgttcccct gctctggcca tgccgctggc gtttccgctt
     5581 gcctatcctg gttccccaaa agggcaacca actggaacgt tttatctgca tggcattatt
     5641 tgtctggtcg gtatggatgc cccattcatt acccgagaac agcgctgttc gttggtcatc
     5701 gcaaatgatc aataccttgc agatccagtt tcatcggctt attaagcatc aggttgaata
     5761 ctaaaaaggc aaaaatcacc tttctggaat aagcaattcc atttgaatat aagagccagc
     5821 tcacagttct gttaatcttg cgccaacact atgactgcta cgcagtgata gaaataataa
     5881 gatcaggaga acggggatga actttccatt aattgcgaac atcgtggtgt tcgttgtact
     5941 gctgtttgcg ctggctcaga cccgccataa acagtggagt ctggcgaaaa aagtgctggt
     6001 gggtctggtg atgggtgtgg tttttggcct tgccctgcat accatttatg gttctgacag
     6061 ccaggtactt aaagattctg tacagtggtt taacatcgtt ggtaacggct atgttcaact
     6121 gctgcaaatg atcgttatgc cgttagtctt cgcctctatt ctgagcgcgg ttgcccgtct
     6181 gcataacgca tctcagttag gcaaaatcag ttttctgacc atcggtacgc ttttgtttac
     6241 cacgctgatt gcggcgctgg tcggtgtgct ggtcaccaac ctgtttggtt tgacggctga
     6301 aggtctggtt cagggtggtg cagaaactgc acgtctgaac gccattgaaa gtaactatgt
     6361 tggtaaagtc tctgatctga gcgttccgca gctggtcttg tcctttatcc cgaaaaaccc
     6421 gtttgccgat cttaccggag ccaatccgac gtcaattatc agcgtggtaa tttttgccac
     6481 attcctcggc gtagctgcat tgaaactgct gaaggatgat gcgccgaaag gtgaacgcgt
     6541 cttagccgct atcgataccc tacaaagctg ggtgatgaaa ctggttcgcc ttgtcatgca
     6601 gttgacccct tacggcgttc tggctctaat gaccaaagtg gttgcaggtt ctaacttgca
     6661 agacatcatc aaactgggaa gtttcgttgt cgcgtcctac ctcggtctgc tgattatgtt
     6721 tgcagtgcat ggcattctgc tgggcattaa tggcgtgagt ccgctgaagt acttccgtaa
     6781 ggtatggcct gtgctgacgt ttgcctttac cagccgttcc agtgctgcgt ctatcccact
     6841 gaatgtggaa gcacaaacgc gtcgtctggg cgttcctgaa tccatcgcca gtttcgccgc
     6901 ctctttcggt gcaaccattg gtcagaacgg ctgcgccggt ttgtatccgg caatgctggc
     6961 ggtgatggtt gcgcctacgg ttggcattaa cccgctggac ccgatgtgga ttgcgacgct
     7021 ggtcggtatt gttaccgtta gttccgcagg cgttgccggt gtcggtggtg gtgcaacttt
     7081 cgccgcactg attgtgctgc ctgcgatggg cctgccagta accctggtgg cgctgttaat
     7141 ctccgttgaa ccgcttatcg acatgggccg tacggcgcta aacgttagtg gctcgatgac
     7201 agctggcacg ctgaccagcc agtggctgaa gcaaaccgat aaagccattc tggatagcga
     7261 agacgacgcc gaactggcac accgttaatt cttatgctgg caacggtccg ttttgtatag
     7321 gggccgttgc tttacttttt aaatgttcca tcgcggcgat gcatactgac tcatatttaa
     7381 acagatcgtc agcgaaaaaa atgtccaact tatcaataca ttcctggctc aatgaatgtg
     7441 cctgtagtga gaagcttaaa acctcatacc cgagacgttt tctaagtgaa ctatctggaa
     7501 tactcataat atcttcaagc acaccacttc ccattcccgg aagatttagt ggattaaaaa
     7561 gaagattgat attaa
//
LOCUS       DAPGUL010000178         7553 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.181, whole genome shotgun sequence.
ACCESSION   DAPGUL010000178 DAPGUL010000000
VERSION     DAPGUL010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7553)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7553)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7553
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.181"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            11..289
                     /gene="yafQ"
                     /locus_tag="RHX21_004385"
     CDS             11..289
                     /gene="yafQ"
                     /locus_tag="RHX21_004385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin YafQ"
                     /protein_id="HDV1989478.1"
                     /translation="MIQRDIEYSGQFSKDVKLAQKRHKDMNKLKYLMTLLINNALPLP
                     AVYKDHPLQGSWKGYRDAHVEPDWILIYKLTDKLLRFERTGTHAALFG"
     gene            445..1185
                     /locus_tag="RHX21_004386"
     CDS             445..1185
                     /locus_tag="RHX21_004386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein L,D-transpeptidase"
                     /protein_id="HDV1989479.1"
                     /translation="MRKIALILAMLLIPCVSFAGLLGSSSSTTPVSKEYKQQLMGSPV
                     YIQIFKEERTLDLYVKMGEQYQLLDSYKICKYSGGLGPKQRQGDFKSPEGFYSVQRNQ
                     LKPDSRYYKAINIGFPNAYDRAHGYEGKYLMIHGDCVSIGCYAMTNQGIDEIFQFVTG
                     ALVFGQPSVQVSIYPFRMTDANMKRHKYSNFKDFWEQLKPGYDYFEQTRKPPTVSVVN
                     GRYVVSKPLSHEVVQPQLASNYTLPEAK"
     gene            complement(1156..1923)
                     /locus_tag="RHX21_004387"
     CDS             complement(1156..1923)
                     /locus_tag="RHX21_004387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II glutamine amidotransferase"
                     /protein_id="HDV1989480.1"
                     /translation="MCELLGMSANVPTDICFSFTGLVQRGGGTGPHKDGWGITFYEGK
                     GCRTFKDPQPSFNSPIAKLVQDYPIKSCSVVAHIRQANRGEVALENTHPFTRELWGRN
                     WTYAHNGQLTGYKSLETGNFRPVGETDSEKAFCWLLHKLTQRYPRTPGNMAAVFKYIA
                     SLADELRQKGVFNMLLSDGRYVMAYCSTNLHWITRRAPFGVATLLDQDVEIDFSSQTT
                     PNDVVTVIATQPLTGNETWQKIMPGEWRLFCLGERVV"
     gene            complement(2129..2707)
                     /gene="lpcA"
                     /locus_tag="RHX21_004388"
     CDS             complement(2129..2707)
                     /gene="lpcA"
                     /locus_tag="RHX21_004388"
                     /EC_number="5.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-sedoheptulose 7-phosphate isomerase"
                     /protein_id="HDV1989481.1"
                     /translation="MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKAG
                     GKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFS
                     RYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEI
                     RVPHFGYADRIQEIHIKVIHILIQLIEKEMVK"
     gene            2947..5391
                     /gene="fadE"
                     /locus_tag="RHX21_004389"
     CDS             2947..5391
                     /gene="fadE"
                     /locus_tag="RHX21_004389"
                     /EC_number="1.3.8.7"
                     /EC_number="1.3.8.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414756.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase FadE"
                     /protein_id="HDV1989482.1"
                     /translation="MMILSILATVVLLGALFYHRVSLFISSLILLAWTAALGVAGLWS
                     AWVLVPLAIILVPFNFAPMRKSMISAPVFRGFRKVMPPMSSTEKEAIDAGTTWWEGDL
                     FQGKPDWKKLHNYPQPRLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLK
                     EHRFFAMIIKKEYGGLEFSAYAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGT
                     DEQKDHYLPRLARGQEIPCFALTSPEAGSDAGAIPDTGIVCMGEWQGQQVLGMRLTWN
                     KRYITLAPIATVLGLAFKLSDPEKLLGGAEDLGITCALIPTTTPGVEIGRRHFPLNVP
                     FQNGPTRGKDVFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALA
                     TGAYAHIRRQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAI
                     VKYHCTHRGQQSIIDAMDITGGKGIMLGQSNFLARAYQGAPIAITVEGANILTRSMMI
                     FGQGAIRCHPYVLEEMEAAKNNDVNAFDKLLFKHIGHVGSNKVRSFWLGLTRGLTSST
                     PTGDATKRYYQHLNRLSANLALLSDVSMAVLGGSLKRRERISARLGDILSQLYLASAV
                     LKRYDDEGRNEADLPLVHWGVQDALYQAEQAMDDLLQNFPNRVVAGLLNVVIFPTGRH
                     YLAPSDKLDHKVAKILQVPNATRSRIGRGQYLTPSEHNPVGLLEEALVDVIAADPIHQ
                     RICKELGKNLPFTRLDELAHNALAKGLIDKDEAAILVKAEESRLRSINVDDFDPEELA
                     TKPVKLPEKVRKVEAA"
     gene            complement(5434..5880)
                     /gene="ivy"
                     /locus_tag="RHX21_004390"
     CDS             complement(5434..5880)
                     /gene="ivy"
                     /locus_tag="RHX21_004390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308274.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ivy family C-type lysozyme inhibitor"
                     /protein_id="HDV1989483.1"
                     /translation="MFKAITTVAALVIATSAMAQDDLTISSLAKGETTKAAFNQMVQG
                     HKLPAWVMKGGTYTPAQTVTLGDETYQVMSACKPHDCGSQRIAVMWSEKSNQMTGLFS
                     TIDEKTSQEKLTWLNVNDALSIDGKTVLFAALTGSLENHPDGFNFK"
     gene            6061..6831
                     /gene="yafV"
                     /locus_tag="RHX21_004391"
     CDS             6061..6831
                     /gene="yafV"
                     /locus_tag="RHX21_004391"
                     /EC_number="3.5.1.111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutaramate amidase"
                     /protein_id="HDV1989484.1"
                     /translation="MPGLKITLLQQPLVWMDGPANLRHFDRQLEGITGRDVIVLPEMF
                     TSGFAMEAAASSLAQDDVVNWMTAKAQQCNALIAGSVALQTESGSVNRFLLVEPGGTV
                     HFYDKRHLFRMADEHLHYKAGNARVIVEWRGWRILPLVCYDLRFPVWSRNLNDYDLAL
                     YVANWPAPRSLHWQALLTARAIENQAYVAGCNRVGSDGNGCHYRGDSRVINPQGEIIA
                     TADAHQATRIDAELSMAVLREYRDKFPAWRDADEFRLR"
     gene            complement(6873..>7553)
                     /locus_tag="RHX21_004392"
     CDS             complement(6873..>7553)
                     /locus_tag="RHX21_004392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
                     /protein_id="HDV1989485.1"
                     /translation="TAIPELLNMLDIKGKIITTDAMGCQKDIAEKIQKQGGDYLFAVK
                     GNQGRLNKAFEEKFPLKELNNPEHDSYAISEKSHGREEIRLHIVCDVPDELIDFTFEW
                     KGLKKLCVAVSFRSIIAEQKKEPEMTVRYYISSADLTAEKFATAIRNHWHVENKLHWR
                     LDVVMNEDDCKIRRGNAAELFSGIRHIAINILTNDKVFKAGLRRKMRNAAMDRNYLAS
                     VLAESGLS"
BASE COUNT         1764 a         1901 c         1984 g         1904 t
ORIGIN      
        1 gaatttaaat atgattcaaa gggatattga atactcggga caattttcaa aggatgtaaa
       61 acttgcacaa aagcgtcata aggatatgaa taaattgaaa tatcttatga cgcttcttat
      121 caataatgct ttaccgcttc cagctgttta taaagaccac ccgctgcaag gttcatggaa
      181 aggttatcgc gatgctcatg tcgaaccgga ctggatcctg atttacaaac ttaccgataa
      241 acttttacga tttgagagaa ctggaactca cgcggcgctc tttgggtaaa gcacgctgcc
      301 gatgaaattt gtaaaccctg cgccgacagg cttgcgtaaa actcttttgg tgataatgtg
      361 agccttccaa atccagacta ttccgatttg ggatctattt tgccgtcctg gcgtgtgtaa
      421 ccgttttatc aaggaataag cagtatgcgt aaaatcgcat taattcttgc gatgttgttg
      481 atcccgtgcg tttcgtttgc cggtttgctg ggcagcagta gctcgaccac gccagtgagc
      541 aaagagtata agcagcagtt gatgggatcc cctgtctaca tccagatctt caaggaagaa
      601 cgtacgctcg atctctacgt caaaatgggc gagcaatatc agctgctcga cagttataaa
      661 atctgtaaat attccggcgg cttagggcca aaacagcgtc agggcgattt caaaagcccg
      721 gaagggtttt atagcgtcca gcgtaatcag ttaaaaccag acagccgtta ctacaaagcg
      781 attaatattg gtttccccaa tgcctatgac cgtgcgcatg gttatgaagg gaaatacctg
      841 atgatccacg gcgattgtgt ttccatcggc tgctacgcaa tgaccaatca gggtattgat
      901 gagatcttcc agttcgttac tggtgcgctg gtgtttggtc agccgagcgt gcaggtgagt
      961 atttacccgt tccgcatgac cgacgccaat atgaagcgcc ataaatattc caactttaag
     1021 gacttctggg agcaactgaa gccgggttac gactactttg agcaaacccg taagccaccg
     1081 accgtttctg tggtcaatgg tcgttacgtg gtcagcaagc cgttaagcca cgaagttgtg
     1141 cagccacaac tggcatcaaa ctacacgctc cccgaggcaa aataagcgcc attcgcctgg
     1201 cataatcttt tgccaggttt cattgcccgt cagcggctgt gttgcaatca ccgtgaccac
     1261 atcattcggt gtggtctgcg agctgaagtc gatttccaca tcctgatcca gcagcgttgc
     1321 cacgccaaac ggcgcgcggc gggtgatcca gtgtaaatta gtcgagcaat acgccatcac
     1381 atagcgcccg tcagaaagca gcatgttgaa aacgcccttc tgccgcagtt catccgccag
     1441 tgaggcgata tatttaaaca ctgccgccat gttgcccggt gtgcgcgggt aacgctgcgt
     1501 taatttatgc aggagccagc agaaggcttt ttcgctatcg gtttcaccga ccgggcggaa
     1561 gttgccggtt tccagtgatt tgtagcccgt cagttgtccg ttatgggcat aagtccagtt
     1621 acgcccccat aactcgcggg taaatgggtg agtattttcc agcgccacct cgccccgatt
     1681 agcctggcga atatgagcca ccaccgaaca ggattttatc gggtagtcct ggacaagttt
     1741 ggcgatgggg gaattaaagc tgggttgtgg atctttaaat gtgcgacagc ctttaccttc
     1801 gtaaaaggta atgccccagc catctttatg tggcccggtt ccaccaccac gctgtacaag
     1861 tccggtgaaa ctaaagcaga tatcggtagg gacgttggcg ctcatcccga gcaattcgca
     1921 catgggtaac ctccacaaca gcgggagcga atggcccccg gcgaagattg atttaagaat
     1981 tttcaggtcg gatgcggcgt aaacgaatta ttcggcctac ggttcgggta cagatttgta
     2041 ggcatgataa gacgcgtcag catcgcatca ggcatcagcg cacaagtgcc ggatgcggcg
     2101 taaacgcctt atccagccta cgccagactt acttaaccat ctctttttca attaactgga
     2161 tcaggatatg gatcacttta atgtgaatct cctgaatgcg gtcggcataa ccaaagtgcg
     2221 gtacgcgaat ttcgatatcc gccgtgccag ccattttgcc gccgtcttta ccggtcaggg
     2281 tgatcacttt catccccttc tcacgcgccg ctgcgatcgc tttgatcacg tttgcagagt
     2341 taccggaggt ggagatcccc agcagtacat cgccttcgcg acctaccgct tcaacgtagc
     2401 gggagaaaat atcattgaaa ccgaaatcat taccgacgca ggaaatatga ctaacgtcag
     2461 aaatagcaat cgccgggtag cccggacggt tttcacggta gcgaccggtc aactcttcgg
     2521 caaagtgcat agcgtcgcaa tgggaacctc cgttgccgca ggaaagcact ttgccaccgg
     2581 ctttaaagct gtctgctaac aggaccgccg cgcgctgaat ggcgtgaata ttggcgtcat
     2641 cttttaaaaa gttagccagc gtttccgccg cttcgttcag ttcgttacga ataagatcct
     2701 ggtacatgag gatatccttc agcataaatg taatagacaa aatgcagtgt accggatacc
     2761 gccaaaagcg agaagtacgg gcaggtgcta tgaccaggac tttttgacct gaagtgcgga
     2821 taaaaacagc aacaatgtga gctttgttgt aattatattg taaacacatt gctaaatgtt
     2881 tttacatcca ctacaaccat atcatcacaa gtggtcagac ctcctacaag taaggggctt
     2941 ttcgttatga tgattttgag tattctcgct acggttgtcc tgctcggcgc gttgttctat
     3001 caccgcgtga gcttatttat cagcagtctg attttgctcg cctggacagc cgccctcggc
     3061 gttgctggtc tgtggtcggc gtgggtactg gtgcctctgg ccattatcct cgtgccattt
     3121 aactttgcgc ctatgcgtaa gtcgatgatt tccgcgccgg tatttcgcgg tttccgtaag
     3181 gtgatgccgc cgatgtcgag cactgagaaa gaagcgattg atgcgggcac cacctggtgg
     3241 gagggcgact tgttccaggg caagccggac tggaaaaagc tgcataacta tccgcagccg
     3301 cgcctgaccg ccgaagagca agcgtttctc gacggcccgg tagaagaagc ctgccggatg
     3361 gcgaatgatt tccagattac tcatgagctg gcggatctgc cgccggagtt gtgggcgtac
     3421 cttaaagagc atcgcttctt cgcgatgatt atcaaaaaag agtacggcgg actggagttc
     3481 tcagcttatg cccagtctcg cgtgctgcaa aaactctccg gcgtgagcgg gatcctggcg
     3541 attaccgtcg gcgtgccgaa ctcattaggc ccgggcgagc tgctgcaaca ttacggcact
     3601 gacgagcaga aagatcacta tctgccgcgt ctggcgcgtg gtcaggagat cccttgcttt
     3661 gcactgacaa gcccggaagc gggttccgat gcgggcgcga ttccggacac cgggattgtc
     3721 tgcatgggcg aatggcaggg ccagcaggtg ctggggatgc gtctgacctg gaacaaacgc
     3781 tatattacgc tggcaccgat tgcgactgtg cttgggctgg cgtttaaact ctccgacccg
     3841 gaaaagctgc tgggtggcgc agaagattta ggtattacct gtgcgctgat cccgaccacc
     3901 acgccgggcg tggaaattgg tcgtcgccac ttcccgctga acgtaccgtt ccagaacgga
     3961 ccgacgcgcg gtaaagatgt cttcgtaccg atcgattaca tcatcggggg gccgaaaatg
     4021 gccgggcaag gctggcggat gctggtggag tgcctctcgg taggccgcgg catcaccctg
     4081 ccttccaact caaccggcgg cgtgaaatcg gtagcgctgg caacgggcgc gtatgctcac
     4141 attcgccgtc agttcaaaat ctctatcggt aagatggaag ggattgaaga gccgctggcg
     4201 cgtattgccg gtaatgccta cgtgatggat gctgcggcat cgctgattac ctacggcatt
     4261 atgctcggcg aaaaacctgc cgtgctgtcg gctatcgtta agtatcactg tacccaccgc
     4321 gggcagcagt cgattattga tgcgatggat atcactggtg gcaaaggcat tatgctcggg
     4381 cagagcaact tcctggcgcg tgcttaccag ggcgcaccga ttgccatcac cgttgaaggg
     4441 gccaacattc tgacccgcag catgatgatc ttcggacaag gagcgattcg ttgccatccg
     4501 tacgtgctgg aagagatgga agcagcgaag aacaatgacg tcaacgcgtt cgataaactg
     4561 ttgttcaaac atatcggtca cgtcggtagc aacaaagttc gcagcttctg gctgggcctg
     4621 acgcgcggtt taaccagcag cacgccaacc ggcgatgcca ctaaacgcta ctatcagcac
     4681 ctgaaccgcc tgagcgccaa cctcgccctg ctttctgatg tctcgatggc tgtgctgggc
     4741 ggcagcctga aacgtcgtga gcgcatctcg gcacgtctgg gggatatttt aagccagctt
     4801 tacctcgcct ctgccgttct gaagcgttat gacgacgaag gccgtaatga agccgacctg
     4861 ccgctggtgc actggggcgt acaagatgcg ctgtatcagg ctgaacaggc gatggatgat
     4921 ttactgcaaa acttcccgaa ccgcgtggtt gccgggctgc tgaatgtggt gatcttcccg
     4981 accggacgtc attatctggc accttctgac aagctggatc ataaagtggc gaagatttta
     5041 caagtgccga acgccacccg ttcccgcatt ggtcgcggtc agtacctgac gccgagcgag
     5101 cataatccgg ttggcttgct ggaagaggcg ctggtggatg tgattgccgc cgacccaatt
     5161 catcagcgga tctgtaaaga gctgggtaaa aacctgccgt ttacccgtct ggatgaactg
     5221 gcgcacaacg cgctggcgaa ggggctgatt gataaagatg aagccgctat tctggtgaaa
     5281 gctgaagaaa gccgtctgcg cagtattaac gttgatgact ttgatccgga agagctggcg
     5341 acgaagccgg taaagttgcc ggagaaagtg cggaaagttg aagccgcgta attgaataac
     5401 ggagccgaaa ggctccgttt ctttatccgc taattattta aaattaaagc catccggatg
     5461 gttttccagg ctgccggtca acgccgcgaa cagcaccgtt ttaccatcaa tcgaaagcgc
     5521 atcgttcaca ttcagccagg tgagtttctc ttgcgacgtt ttctcatcaa tagtcgagaa
     5581 cagccccgtc atctgattag atttctcgga ccacatcaca gcgatacgtt gcgagccaca
     5641 gtcatgcggt ttgcacgcgc tcatcacctg atacgtctca tctcccaacg ttacggtttg
     5701 tgcgggagta taagtaccgc ctttcatcac ccaggcaggc agcttatgcc cttgtaccat
     5761 ctgattaaat gcagctttgg tggtttcgcc ctttgcaagg ctgctaatgg ttaaatcatc
     5821 ctgcgccatt gcactggtgg cgatgaccag agcggcgact gtcgttattg ccttaaacat
     5881 cattcctccc gagcttatcc tgcccatgtt attaaccttc taaagcctgg cgataacacg
     5941 ataatttgca aatcagatat ttccaatatc agcatttgtt atcaatttat tctgcgctaa
     6001 ggcaactgcc tgataaggtg ttaaagttat aaaacccttc gcataaagga gttgtacacc
     6061 gtgcctggtt tgaagattac gcttttgcag caaccactgg tgtggatgga tggccctgcc
     6121 aacctgcgtc attttgatcg tcaactggaa ggtattaccg ggcgcgatgt gatcgttcta
     6181 ccggagatgt ttaccagcgg ctttgccatg gaagcggcag cttcgtcgct agcacaagat
     6241 gacgtagtga actggatgac agctaaggcg cagcagtgca atgcgctgat tgcaggcagt
     6301 gttgcattac aaacggagtc tggttcggtt aaccgctttt tgctggttga gccgggcggc
     6361 acggtacatt tttatgataa gcgtcatctg ttccgcatgg cagatgagca tctacattat
     6421 aaagcgggca atgcgcgagt gattgtggaa tggcgcggct ggcgtatttt gccgctggtg
     6481 tgctacgact tacgttttcc tgtgtggtcg cgcaatctca acgattatga cctcgccctg
     6541 tacgtcgcca actggcctgc tccgcgctct ctgcactggc aggcattgct gacggcccgc
     6601 gcgattgaga atcaggcgta tgtggcggga tgcaatcgcg tcggcagcga tggcaacggc
     6661 tgccattatc gcggtgacag ccgggtgatt aatccacaag gcgagattat cgctactgcc
     6721 gacgcgcatc aggcaacgcg cattgatgcc gagctgtcga tggcggtgtt aagggaatat
     6781 cgcgataagt ttccggcatg gcgggatgcg gatgagttta ggttgcggtg agtgggggtt
     6841 gtgtttaagg ctgggggaga gtcggggtaa gactacgaaa gcccgctctc cgcaaggact
     6901 gacgccagat agtttctgtc catagctgca tttcgcatct tacgtcttaa ccctgccttg
     6961 aataccttat cattcgtcaa aatattaata gcgatgtgcc gtatccctga aaataattct
     7021 gctgcatttc ctcttcttat tttgcagtcg tcttcattca ttaccacgtc cagacgccag
     7081 tgcagcttat tctccacgtg ccagtggttt cggattgctg tggcgaactt ctctgcggtt
     7141 aaatcagcag aactgatata atatctgacc gtcatttctg gctctttctt ttgttctgct
     7201 attatggacc gaaaggagac tgccacgcat aatttcttca gccctttcca ttcaaacgtg
     7261 aaatcaataa gttcatcagg gacatcgcaa acaatatgaa gacggatttc ttctctgccg
     7321 tgactctttt cactgattgc gtaactgtca tgctctggat tatttaattc tttcagcgga
     7381 aatttttcct caaaggcttt attaagccgc ccctggtttc cttttaccgc gaataaataa
     7441 tcaccgccct gtttttgtat cttctctgca atatctttct ggcatcccat cgcatcagtt
     7501 gtgatgattt ttcctttaat atccagcatg ttaagaagtt ctgggatagc tgt
//
LOCUS       DAPGUL010000179         7374 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.182, whole genome shotgun sequence.
ACCESSION   DAPGUL010000179 DAPGUL010000000
VERSION     DAPGUL010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7374)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7374)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7374
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.182"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(91..914)
                     /locus_tag="RHX21_004393"
                     /pseudo
     CDS             complement(91..914)
                     /locus_tag="RHX21_004393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414735.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YaeF family permuted papain-like enzyme"
     gene            complement(968..2686)
                     /gene="proS"
                     /locus_tag="RHX21_004394"
     CDS             complement(968..2686)
                     /gene="proS"
                     /locus_tag="RHX21_004394"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDV1989486.1"
                     /translation="MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLP
                     TGVRVLKKVENIVREEMNNAGAIEVSMPVVQPADLWQESGRWEQYGPELLRFVDRGER
                     PFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDA
                     YSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGE
                     DDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLVDTPNAKTIAELVEQFNLPIEK
                     TVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAG
                     PGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEVADIRNVVA
                     GDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTR
                     VVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVL
                     LDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVEYL
                     VKQIKG"
     gene            complement(2798..3505)
                     /gene="tsaA"
                     /locus_tag="RHX21_004395"
     CDS             complement(2798..3505)
                     /gene="tsaA"
                     /locus_tag="RHX21_004395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase
                     TrmO"
                     /protein_id="HDV1989487.1"
                     /translation="MSSFQFEQIGVIRSPYKEKFAVPRQPGLVKSANGELHLIAPYNQ
                     ADAVRGLEAFSHLWILFVFHQTMEGGWRPTVRPPRLGGNARMGVFATRSTFRPNPIGM
                     SLVELKEVVCHKDSVILKLGSLDLVDGTPVVDIKPYLPFAESLPDASASYAQSAPAAE
                     MAVSFTAEVEKQLLTLEKRYPQLTLFIREVLAQDPRPAYRKGEETGKTYAVWLHDFNV
                     RWRVTDAGFEVFALEPR"
     gene            complement(3502..3906)
                     /gene="rcsF"
                     /locus_tag="RHX21_004396"
     CDS             complement(3502..3906)
                     /gene="rcsF"
                     /locus_tag="RHX21_004396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rcs stress response system protein RcsF"
                     /protein_id="HDV1989488.1"
                     /translation="MRALPICLVALMLSGCSMLSRSPVESVQSTAPQPKAEPAKPKAP
                     RATPVRIYTNAEELVGKPFRDLGEVSGDSCQASNQDSPPSIPTARKRMQINASKMKAN
                     AVLLHSCEVTSGTPGCYRQAVCIGSALNITAK"
     gene            complement(4024..4839)
                     /gene="metQ"
                     /locus_tag="RHX21_004397"
     CDS             complement(4024..4839)
                     /gene="metQ"
                     /locus_tag="RHX21_004397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter substrate-binding
                     lipoprotein MetQ"
                     /protein_id="HDV1989489.1"
                     /translation="MAFKFKTFAAVGALIGSLALVGCGQDEKDPNHIKVGVIVGAEQQ
                     VAEVAQKVAKDKYGLDVELVTFNDYVLPNEALSKGDIDANAFQHKPYLDQQLKDRGYK
                     LVAVGNTFVYPIAGYSKKIKSLDELQDGSQVAVPNDPTNLGRSLLLLQKVGLIKLKDG
                     VGLLPTVLDVVENPKNLKIVELEAPQLPRSLDDAQIALAVINTTYASQIGLTPAKDGI
                     FVEDKDSPYVNLIVTREDNKDAENVKKFVQAYQSDEVYEAANKVFNGGAVKGW"
     gene            complement(4879..5532)
                     /gene="metI"
                     /locus_tag="RHX21_004398"
     CDS             complement(4879..5532)
                     /gene="metI"
                     /locus_tag="RHX21_004398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease MetI"
                     /protein_id="HDV1989490.1"
                     /translation="MSEPMMWLLVRGVWETLAMTFVSGFFGFVIGLPVGVLLYVTRPG
                     QIIANAKLYRTVSAIVNIFRSIPFIILLVWMIPFTRVIVGTSIGLQAAIVPLTVGAAP
                     FIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGY
                     SAMGGAVGAGGLGQIGYQYGYIGYNATVMNTVLVLLVILVYLIQFAGDRIVRAVTRK"
     gene            complement(5525..6556)
                     /gene="metN"
                     /locus_tag="RHX21_004399"
     CDS             complement(5525..6556)
                     /gene="metN"
                     /locus_tag="RHX21_004399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014168731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein
                     MetN"
                     /protein_id="HDV1989491.1"
                     /translation="MIKLSNITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGK
                     STLIRCVNLLERPTEGSVLVDGQELTTLSESELTKARRQIGMIFQHFNLLSSRTVFGN
                     VALPLELDNTPKDEIKRRVTELLSLVGLGDKHDSYPSNLSGGQKQRVAIARALASNPK
                     VLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVISNGE
                     LIEQDTVSEVFSHPKTPLAQKFIQSTLHLDIPEDYQERLQAEPFTDCVPMLRLEFTGQ
                     SVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHH
                     VKVEVLGYV"
     gene            6744..7316
                     /gene="gmhB"
                     /locus_tag="RHX21_004400"
     CDS             6744..7316
                     /gene="gmhB"
                     /locus_tag="RHX21_004400"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HDV1989492.1"
                     /translation="MAKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKK
                     MGFALVVVTNQSGIARGKFTEAQFETLTEWMDWSLADRDVDLDGIYYCPHHPQGSVEE
                     FRQVCDCRKPHPGMLLSARDYLHIDMAASYMVGDKLEDMQAAAAANVGTKVLVRTGKP
                     ITPEAENAADWVLNSLADLPQAIKKQQKPA"
BASE COUNT         1808 a         1906 c         1872 g         1788 t
ORIGIN      
        1 tataatgcaa cattttgaat tagcacgatt ttgtaggccg gataaggcgt ttacgccgca
       61 tccggcattt tgtgcacgag gctggcttta tcactgagtc agcccaacaa agcgacccgc
      121 cttgatataa atcccaggct tcaggtgccc aacatactgt aactgcgttt ctggcttaaa
      181 cgcagagaca tcaccaatac gcatatgcat cagatcggca gggctaatcc agcccgattg
      241 cgccagtgta agtggatgcc cggctttggc aaaggcatcc gtgacaaatt ccgaacaaaa
      301 ccacgacttt ttgtctcctt cgcccacact gcttaactgc gctttcgcca ggccgctgac
      361 gcactttggc gaaaatcctc ggagaacgga ttcagtgagc acatctggcg agtcaccata
      421 aagggaataa attcgacaat gccgcgatag ttataaccgc tatctttgat tttattggca
      481 aacgcggtga tatctgtggc ttgttgcggg gtaagatccg ggactcgtaa gacgaaaagc
      541 ttatcactat gcttcatcgc ttttttaagg gaaacaatct ggacgccagc gcctgtcgct
      601 tctgcaacgt tattatcacc cagaaagatt gcaacgtgac tcacagagga agtgctgaag
      661 acgcggattc caaatgaggt taccccaagg cttgaggaga acagcaaatc gccgggtttg
      721 agatcaggtg ccgttatttc ttttattgat tgttcggtga aagagctttg atgctggaat
      781 ttgacagccc atgtttttgc ctcggcatct actgctgtgg ctgatgggtc tggctggctg
      841 atatcaacgg tacaagccga aagtaaaaga aagctgggga gaaacaggcg gcagtacgcc
      901 tttggtttat ccattttata caatccatgt aaaaaaaggg ccctgaaatt caggaccctt
      961 tctggcatca gcctttaatc tgtttcacca gatattcgac gatgtcacca gtcttaatta
     1021 actgtttctc gccgttgcga cgatatttat attcgatatc gtcgttgtcg aggttacggt
     1081 cgcccagcac aatagtgtgc ggaataccga tcagttccat atcagcaaac atcacgcccg
     1141 gacgctcttt gcggtcatcc agcagcactt cgataccttg tgcacgcagt tcgctgtaca
     1201 gtttctcagc aagctcttgt acgcggaagg atttgtgcat gttcatcggc agaatcgcca
     1261 cctggaacgg cgcgatagcg tcaggccata cgatgcctcg ttcgtcgtag ttctgctcaa
     1321 tcgccgcagc taccacacgc gttaccccga taccgtagca acccatcgtc aggatttggt
     1381 tacggccatc ttcaccctgt acggaggctt tcagtgcttc ggagtacttg gtacccagct
     1441 ggaagatgtg accaacttcg ataccacgtt tgatcagcag cgtaccctgg ccatccgggc
     1501 ttggatcgcc agccaccacg ttacggatat ctgcaacttc cggggtagcg acatcgcgat
     1561 cccagttgat gccgaagtag tgtttaccat cgatgttagc accagcagcg aaatcactca
     1621 tcgccgcaac ggtacggtca atcaccaccg gaatcggcat gtttaccgga cccagtgaac
     1681 ccggaccggc tttaaccacg gcacgaattt cttcttcggt cgcgaaagtc agcgggcttg
     1741 caacctgcgg cagtttttct gctttaactt cgttcagctc gtgatcaccg cgcaccagca
     1801 gcgcaaccag cgggaagcta ctgccttcaa ccgctttaac cagcagagtc ttaaccgttt
     1861 tctcaatcgg cagattgaac tgttcaacca gttccgcgat ggttttcgcg ttcggcgtat
     1921 caaccagcgt catttcctgg gtagcagcag cgcgcggttc tttcggcgcg atagcttctg
     1981 ccagttcaat gttcgctgca tagtcagagg tgtcggagaa gaccacatcg tcttcaccgc
     2041 tctgcgccag cacctggaat tcgtgagagg cgctgccgcc gatagaaccg gtgtcggctt
     2101 gtacggcgcg gaaatccagc cccatgcggc tgaagatttt gctgtaggcc gcatacattg
     2161 catcgtaggt ttcctgcagg gattcctgag aagtatggaa agagtaagca tctttcatca
     2221 ggaattcgcg ggaacgcatg acgccgaaac gcggacgcac ttcgtcgcgg aacttggtct
     2281 ggatctgata gaagttcagc ggcagctgtt tgtaagagct aagctcgtta cgaatcaggt
     2341 cagtgataac ttcttcatga gttgggccga gtacgaacgg acgctcgcca cggtcaacaa
     2401 aacgcagcag ttccggaccg tactgttccc aacgaccact ctcttgccac aaatcagctg
     2461 gctgaaccac cggcatcgac acctcgatcg caccggcgtt gttcatctct tcacgcacga
     2521 tgttttcgac ttttttcaga acgcgcacgc cggtcggcag ccaggtatat aacccggagg
     2581 ccagcttgcg gatcatcccg gcgcgcagca tcagctgatg gctgatcacc tcggcgtcgg
     2641 caggtgtctc cttgagagtg gagagcaggt attggctagt acgcatgttg ttacggttcc
     2701 agttggaagg tagaacaggc tcaaggcgag cctgggacaa aaaaaagtga tttagtttac
     2761 cagtgcaaaa gaaatgtcaa aagagaaggg cgtgaattta acgcggttcc agcgcaaaga
     2821 cttcaaaacc tgcgtcggtg acgcgccagc gaacgttaaa atcatgtagc cagacggcat
     2881 aggttttgcc cgtttcctca cctttacgat aggccgggcg tgggtcctgc gccagtactt
     2941 cgcggataaa cagcgttaac tgcggataac gcttctccag cgtcaaaagc tgcttttcga
     3001 cctctgcggt aaaactcacc gccatctctg ccgctggcgc actttgcgca tagctggcac
     3061 tggcatcggg aagcgattcg gcaaagggga gatacggttt gatatccact accggcgtac
     3121 catcgaccag atccagactg ccgagcttca gaatcacgct gtctttatgg caaacaacct
     3181 ctttcagctc taccagcgac ataccaattg ggttagggcg gaaagtagag cgtgttgcga
     3241 aaacccccat tctggcgtta ccgccgaggc gcggtggacg cacagtcgga cgccagccgc
     3301 cttccatcgt ttgatgaaag acgaaaagga tccataaatg gctgaacgct tccaggccgc
     3361 gaacggcgtc ggcctggttg tagggagcaa tgagatgcag ttcgccgttg gcgcttttta
     3421 ccagacctgg ctggcgcgga acggcgaatt tttctttata gggcgagcga ataacgccta
     3481 tttgctcgaa ctggaaactg ctcatttcgc cgtaatgtta agcgcagagc cgatacatac
     3541 agcctgacga tagcagcctg gcgtaccgct ggtgacttcg cagctatgca gtaataccgc
     3601 attggccttc attttcgagg cgttgatttg catccgctta cgcgcggttg gaatgctcgg
     3661 cggagagtcc tgattagagg cctggcaaga gtcgccactg acttcaccga gatcgcggaa
     3721 cggtttgccg actaattctt ctgcattggt ataaattcgg accggcgtgg cgcgcggcgc
     3781 tttcggtttt gcaggctccg ctttcggctg gggtgcagtg ctttgaacgg attcgacagg
     3841 ggatctgctt aacatggaac agccgcttag catgagtgct actaaacaga tcggtaaagc
     3901 acgcatagta tttcctcaat gtatgatcaa aacgtcaata ttgaatcagg agcttgtaaa
     3961 aatgacaaga cgggcaagcg cccgtcctga atgatattac aaattgtgga aacagcctaa
     4021 aaattaccag cctttaacag cgccgccgtt aaacactttg tttgctgctt cgtaaacttc
     4081 atcagactga taagcctgga cgaatttctt cacgttctcg gcgtctttgt tatcttcacg
     4141 cgttacgatc aggtttacgt acggggagtc tttatcttcg acaaagatac cgtctttcgc
     4201 tggagtcagg ccaatctggc tggcataggt ggtattgata actgccagag cgatttgcgc
     4261 gtcgtccaga gatcgaggca gctgcggtgc ttccagctca acaattttca gattttttgg
     4321 gttctcaaca acatcaagaa cggtcggcag caggccaacg ccatctttca gtttgatcaa
     4381 gcccactttt tgcagcagca gcagtgaacg accaagatta gttggatcgt ttggcacggc
     4441 aacctgcgaa ccatcctgca gttcatccag tgatttgatt ttcttggagt aaccagcaat
     4501 cggataaaca aaagtgttgc ctactgcgac cagtttgtag ccacgatctt tcagttgctg
     4561 atcaaggtac ggtttatgct ggaaggcgtt ggcgtcgata tcgcctttgc tcaatgcttc
     4621 gtttggcaga acatagtcgt tgaaggttac cagctcaacg tccaggccat atttgtcttt
     4681 cgcaactttc tgcgcgactt ctgctacctg ctgttcggca ccaacaatca cgccgacttt
     4741 aatgtggttt ggatcttttt catcctgacc gcagcctacc agtgccagtg atccaatcag
     4801 ggctcccact gccgcaaagg ttttgaattt gaacgccata ccttattcct tcttcaatta
     4861 tttatgttgt gttgaacgtt acttgcgagt gacagcccgg acgatgcggt cgcctgcgaa
     4921 ctgaattaaa taaaccagaa tgaccagcaa taccagtacc gtattcatca ccgtcgcgtt
     4981 atagccgatg tagccatact gatagccaat ctgacctaaa ccaccggcac cgactgcacc
     5041 acccatcgcg gaataaccga ccagggtaat cagggtgata gttgccgcat tcaccagacc
     5101 cggcaatgct tccggtaaca gcactttacg gacgatctgc atcggcgtgg cacccattgc
     5161 acgggaagct tcaattaacc cggttgggat ctccagcaga gcgttctcga ccatacgggc
     5221 aataaacggt gctgcaccaa cggttaacgg aacaatcgct gcctgcaaac caatcgatgt
     5281 accgacaata acgcgggtaa acggaatcat ccataccagc aagataatga acgggatgga
     5341 acggaaaatg ttcacaatcg cagaaacggt acgatacagc ttcgcgttag caataatttg
     5401 ccccgggcgc gtaacataaa gcaggacgcc gaccggcaga ccaatcacaa agccaaaaaa
     5461 tccggatacg aaggtcattg ccagcgtttc ccatacgcca cgaaccagca accacatcat
     5521 cggctcagac ataacccagt acctctactt ttacatggtg ttcctgcagc caggcaatgg
     5581 cggcttgcgt atcttgttgt gtgccgtgca tttcagtcag catgatgccg aacttaacgc
     5641 caccggcgta atccatctgc gcgctaataa tgttgttgtt gacgttgaaa cgacgcgcgg
     5701 tttcagaaag cagcggggca tcgaccgatt gaccggtaaa ctccaggcgc aacatcggca
     5761 cgcagtcagt aaatggctcc gcttgcagac gttcctggta atcttccggg atatccagat
     5821 gcagggtcga ctgaataaac ttctgcgcca gcggcgtttt cggatgcgag aacacttcac
     5881 ttaccgtgtc ctgctcgatc agttcgccat tgctgatgac cgccacgcaa tcacaaatac
     5941 gcttcacaac gtccatttcg tgggtgatca acagaatcgt caaacccaga cggcggttaa
     6001 tgtctttcag cagttcgaga atagaacgtg tcgttgccgg gtccagcgcg ctggtggctt
     6061 catcacacag caatactttg ggattgctgg ctaatgcacg ggcaatcgcc acacgttgtt
     6121 tctgcccacc ggaaagattc gacgggtagc tatcatgctt atcgccaaga ccaaccaatg
     6181 acagcaattc cgtcacgcga cgtttgatct cgtctttcgg tgtgttgtcc agctccagcg
     6241 gcagagccac gttgccaaaa acagtacgcg aagagagcag gttaaaatgc tggaaaatca
     6301 taccaatctg gcggcgagct ttggtcaact cggattctga cagcgtggtc agttcctggc
     6361 catcgaccag cacgctaccc tcggttgggc gctccagcag gtttacacaa cgtataagcg
     6421 tactcttacc cgcgcctgag gcaccgataa cgccataaat ttgtccagct ggcacatgca
     6481 ggctgacgtt gttcaacgcc tggatggtgc gggtgccctg gtggaacact ttggtgatat
     6541 tcgaaagttt tatcattgat tatttattat cgtcattaag ttagtcgtgg catttcgaat
     6601 gcctgaaacg ggcaacgccg tcaatgaaat ggatgttaag gcatccagac gtctaaatca
     6661 atcaggttta tgcgaagagc actttcttgc aggtcgaaac atgcgatact agcgtcacat
     6721 gccttattaa ggagctataa aaggtggcga agagcgtacc cgcaattttt cttgaccgtg
     6781 atggcaccat taatgtcgat cacggctatg tccatgagat cgacaacttt gaatttatcg
     6841 acggtgttat tgacgccatg cgcgagctaa aaaaaatggg ctttgcgctg gtggtagtaa
     6901 ccaaccagtc tggcattgct cgcggtaaat ttactgaagc gcagtttgaa acgctgaccg
     6961 agtggatgga ctggtcgctg gcggaccgcg atgtcgatct ggatggcatc tattattgcc
     7021 cgcatcatcc gcagggtagt gttgaagagt ttcgccaggt ctgcgactgc cgcaaaccac
     7081 atccggggat gcttttgtca gcacgcgatt atttgcatat tgatatggcc gcttcttata
     7141 tggtgggcga taaattagaa gatatgcagg cagcggctgc ggcgaacgtg ggaacaaaag
     7201 tgctggtgcg tacgggtaaa cctattacgc ctgaagcaga aaacgcggcg gattgggtgt
     7261 taaatagcct ggcagacctg ccgcaagcga taaaaaagca gcaaaaaccg gcataatgat
     7321 taaaagatga gcaattgaaa taaaaatgca tttttccact tgtcttcctg agac
//
LOCUS       DAPGUL010000180         7250 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.184, whole genome shotgun sequence.
ACCESSION   DAPGUL010000180 DAPGUL010000000
VERSION     DAPGUL010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7250)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7250)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7250
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.184"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..342
                     /locus_tag="RHX21_004401"
     CDS             <1..342
                     /locus_tag="RHX21_004401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309324.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDV1989493.1"
                     /translation="AWHTRLMEDGVQAMRDYLAGLDIASPEHQVLMNVTAKSEVAPSI
                     IKENLSLHLTHTVKWTESLDTFLNMPTPVAFLEISNKPYLGNMLNDFAGVDQQRVMHC
                     RKAFSDAKVFK"
     gene            339..1325
                     /locus_tag="RHX21_004402"
     CDS             339..1325
                     /locus_tag="RHX21_004402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989494.1"
                     /translation="MIPDYLTFIRFQDKRNLIYIYAIGLILIGFYWKNAGFTFPSEDI
                     GVVSGILALVLYNFIFDLKAYWAYKCVTKNIDFSWFKKKQNHKIELFLTQPLVAGFLS
                     LIMLSAMSWGLYQLLPSLYALFLISLLGPLVIFLLFRMIRTSYVKQVAISVAKKVKYK
                     SLTRYVLLSVCISTVVNLLTISPLRNSDSFVTEGQWLTFKSIIALLILCGVVLAINLF
                     FLRFSKRYAFLGRLFLQEIDLFFSSENALSTFFAKPLWLRLFILLVIEMMWITLVSVL
                     ATLVEWRIWFEAYFLLCYVPCLIYYFFHCRCLWHNDFMMACDMYFRWGHFNK"
     gene            complement(1518..1605)
                     /locus_tag="RHX21_004403"
     tRNA            complement(1518..1605)
                     /locus_tag="RHX21_004403"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1569..1571),aa:Ser,seq:gga)
     gene            1839..2777
                     /gene="ghrA"
                     /locus_tag="RHX21_004404"
     CDS             1839..2777
                     /gene="ghrA"
                     /locus_tag="RHX21_004404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415551.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate/hydroxypyruvate reductase GhrA"
                     /protein_id="HDV1989495.1"
                     /translation="MDIIFYHPTFDTQWWIEALRKAIPQARVRAWKSGDNDSADYALV
                     WHPPVEMLAGRDLKAVFALGAGVDSILSKLQAHPEMLNPSVPLFRLEDTGMGEQMQEY
                     AVSQVLHWFRRFDDYRIQQNSSHWQPLPEYHREDFTIGILGAGVLGSKVAQSLQTWRF
                     PLRCWSRTRKSWPGVQSFAGREELSAFLSQCRVLINLLPNTPETVGIINQQLLEKLPD
                     GAYLLNLARGVHVVEDDLLAALDSGKVKGAMLDVFNREPLPPESPLWQHPRVTITPHV
                     AAITRPAEAVEYISRTIAQLEKGERVCGQVDRARGY"
     gene            2832..3569
                     /gene="ycdX"
                     /locus_tag="RHX21_004405"
     CDS             2832..3569
                     /gene="ycdX"
                     /locus_tag="RHX21_004405"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding phosphatase"
                     /protein_id="HDV1989496.1"
                     /translation="MYPVDLHMHTVASTHAYSTLSDYIAQAKQKGIKLFAITDHGPDM
                     EDAPHHWHFINMRIWPRVVDGVGILRGIEANIKNVDGEIDCSGKMFDSLDLIIAGFHE
                     PVFAPHDKATNTQAMIATIASGNVHIISHPGNPKYEIDVKAVAEAAAKHQVALEINNS
                     SFLHSRKGSEDNCRAVAAAVRDAGGWVALGSDSHTAFTMGEFEECLKILDAVDFPPER
                     ILNVSPRRLLNFLESRGMAPIAEFADL"
     gene            3593..4147
                     /gene="ycdY"
                     /locus_tag="RHX21_004406"
     CDS             3593..4147
                     /gene="ycdY"
                     /locus_tag="RHX21_004406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone YcdY"
                     /protein_id="HDV1989497.1"
                     /translation="MNEFSILCRVLGSLYYRQPQDPLLVPLFTLIREGKLAANWPLEQ
                     DELLTRLQKSCDMAQVSADYNALFIGDECAVPPYRSAWVEDATEAEVRAFLSERGMPL
                     ADTPADHIGTLLLAASWLEDQSTEDESEALETLFSEYLLPWCGAFLGKVEAHATTPFW
                     RTMAPLTRDAISAMWDELEEDSEE"
     gene            4249..4740
                     /locus_tag="RHX21_004407"
     CDS             4249..4740
                     /locus_tag="RHX21_004407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415554.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HDV1989498.1"
                     /translation="MNILLSIAITTGILSGIWGWVAVSLGLLSWAGFLGCTAYFACPQ
                     GGLKGLAISAATLLSGVVWAMVIIYGSALAPHLEILGYVITGIVAFLMCIQAKQLLLS
                     FVPGTFIGACATFAGQGDWKLVLPSLALGLVFGYAMKNSGLWLAARSAKTAHREQEIK
                     NKA"
     gene            complement(4804..5637)
                     /gene="csgG"
                     /locus_tag="RHX21_004408"
     CDS             complement(4804..5637)
                     /gene="csgG"
                     /locus_tag="RHX21_004408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgG"
                     /protein_id="HDV1989499.1"
                     /translation="MQRLFLLVAVMLLSGCLTAPPKEAARPTLMPRAQSYKDLTHLPA
                     PTGKIFVSVYNIQDETGQFKPYPASNFSTAVPQSATAMLVTALKDSRWFIPLERQGLQ
                     NLLNERKIIRAAQENGTVAINNRIPLQSLTAANIMVEGSIIGYESNVKSGGVGARYFG
                     IGADTQYQLDQIAVNLRVVNVSTGEILSSVNTSKTILSYEVQAGVFRFIDYQRLLEGE
                     VGYTSNEPVMLCLMSAIETGVIFLINDGIDRGLWDLQNKAERQNDILVKYRHMSVPPE
                     S"
     gene            complement(5664..6080)
                     /gene="csgF"
                     /locus_tag="RHX21_004409"
     CDS             complement(5664..6080)
                     /gene="csgF"
                     /locus_tag="RHX21_004409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgF"
                     /protein_id="HDV1989500.1"
                     /translation="MRVKHAVVLLMLISPLSWAGTMTFQFRNPNFGGNPNNGAFLLNS
                     AQAQNSYKDPSYNDDFGIETPSALDNFTQAIQSQILGGLLSNINTGKPGRMVTNDYIV
                     DIANRDGQLQLNVTDRKTGQTSTIQVSGLQNNSTDF"
     gene            complement(6105..6494)
                     /gene="csgE"
                     /locus_tag="RHX21_004410"
     CDS             complement(6105..6494)
                     /gene="csgE"
                     /locus_tag="RHX21_004410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgE"
                     /protein_id="HDV1989501.1"
                     /translation="MKRYLRWIVAAEFLFAAGNLHAVEVEVPGLLTDHTVSSIGHDFY
                     RAFSDKWESDYTGNLTINERPSARWGSWITITVNQDVIFQTFLFPLKRDFEKTVVFAL
                     IQTEEALNRRQINQALLSTGDLAHDEF"
     gene            complement(6499..7149)
                     /gene="csgD"
                     /locus_tag="RHX21_004411"
     CDS             complement(6499..7149)
                     /gene="csgD"
                     /locus_tag="RHX21_004411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator CsgD"
                     /protein_id="HDV1989502.1"
                     /translation="MFNEVHSIHGHTLLLITKPSLQATALLQHLKQSLAITGKLHNIQ
                     RSLDDISSGSIILLDMMEADKKLIHYWQDTLSRKNNNIKILLLNTPEDYPYRDIENWP
                     HINGVFYAMEDQERVVNGLQGVLRGECYFTQKLASYLITHSGNYRYNSTESALLTHRE
                     KEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR"
BASE COUNT         1800 a         1616 c         1771 g         2063 t
ORIGIN      
        1 gcctggcaca cgcgtttgat ggaagacggc gttcaggcaa tgcgcgatta tcttgccgga
       61 ctggatatcg cttcgccaga gcatcaggtt ctgatgaacg taacagcaaa aagcgaggtc
      121 gctccgtcaa ttatcaaaga aaatctctca ttacacttaa cccatacggt gaaatggact
      181 gaatctctcg atacatttct gaatatgcca accccggtag ctttccttga aataagtaat
      241 aagccctatt tggggaatat gttaaatgat tttgctggcg tggatcagca acgagttatg
      301 cattgtcgta aagcatttag tgatgcaaag gtattcaaat gattcctgat tatttaactt
      361 ttattcgctt tcaggataaa cgaaatctga tatacattta tgctattgga cttattctga
      421 taggctttta ttggaaaaat gcaggattta cttttccatc agaggatatt ggtgtcgtta
      481 gtgggattct ggccctggtg ctgtataatt ttatttttga tctcaaggcg tactgggctt
      541 ataaatgcgt cacgaagaat atcgattttt cgtggtttaa gaaaaagcag aaccacaaaa
      601 tagaattatt tcttacacaa cctctggtgg caggatttct gtcgttaatc atgttgagtg
      661 caatgagttg ggggctatac cagcttctac cctcgttata tgcgctgttc ctgatttcgt
      721 tacttgggcc gttggtcatc tttctgctgt ttcggatgat ccgcaccagt tatgtcaagc
      781 aggtcgctat ttcagtagcg aaaaaagtaa aatataaaag tctgactcgc tatgtgctgc
      841 tttcggtgtg catctcaacg gttgttaacc tgcttactat cagcccgtta cgtaacagtg
      901 attcttttgt gacagagggg cagtggttaa cgtttaaatc gataattgca ttgctcattc
      961 tttgtggcgt agtgttggcg attaatctgt tttttctgcg cttctccaag cggtacgctt
     1021 ttctgggcag gctttttttg caggaaatcg atctgttttt ctccagtgaa aatgcgttgt
     1081 cgaccttttt tgccaagccg ctttggcttc ggttattcat attgctggtt attgaaatga
     1141 tgtggattac gctggtgtcg gtattggcaa cgcttgtaga atggcggatt tggtttgaag
     1201 cctatttttt actctgctat gtaccgtgct taatttacta ttttttccat tgtcgatgcc
     1261 tctggcataa cgattttatg atggcatgtg acatgtattt ccgttggggg cattttaata
     1321 agtgaggaag ttacaggaag tgaccagata acgcatatat gttctctact atcttgcgca
     1381 ttttgattgt tgactgagta accagacagt tgatgtgcac aatttcccct cgccctaaca
     1441 gacgtgggcg ggggcacccg gtgtgtgcaa tatacgaaaa aaaagcccgt actttcgtac
     1501 gggctcttct ttaaatatgg cggtgagggg gggattcgaa cccccgatac gttgccgtat
     1561 acacactttc caggcgtgct ccttcagcca ctcggacacc tcaccaaatt gtcgttcctg
     1621 tcttgctgga acgggcgcta atttagggaa atcatgacct gaggtcaaca aactttttga
     1681 aaaaatcgcg cgtttattca aacttcaatc aatgtgtggt tttagtaagc gaaatctgct
     1741 ttttttgcca ccgaccacgg atttgttatg ctggtggcct ttgtagatca taacgataag
     1801 tgcgaataaa tttcgcacaa cgcttttcgg gagtcagtat ggatatcatc ttttatcacc
     1861 caacgttcga tacccaatgg tggattgagg cactgcgcaa agctattcct caggcaagag
     1921 tcagagcatg gaaaagcgga gataatgact ctgctgatta tgctttagtc tggcatcctc
     1981 ctgttgaaat gctggcaggg cgcgatctta aagcggtgtt cgcactcggg gccggtgttg
     2041 attctatttt gagcaagcta caggcacacc ctgaaatgct gaacccttct gttccacttt
     2101 ttcgcctgga agataccggt atgggcgagc aaatgcagga atatgctgtc agtcaggtgc
     2161 tgcattggtt tcgacgtttt gacgattatc gcatccagca aaatagttcg cattggcaac
     2221 cgctgcctga atatcatcgg gaagatttta ccatcggcat tttgggcgca ggcgtactgg
     2281 gcagtaaagt tgctcagagt ctgcaaacct ggcgctttcc gctgcgttgc tggagtcgaa
     2341 cccgtaaatc gtggcctggc gtgcaaagct ttgccggacg ggaagaactg tctgcatttc
     2401 tgagccaatg tcgggtattg attaatttgt taccgaatac ccctgaaacc gtcggcatta
     2461 ttaatcaaca attactcgaa aaattaccgg atggcgcgta tctcctcaac ctggcgcgtg
     2521 gtgttcatgt tgtggaagat gacctgctcg cggcgctgga tagcggcaaa gttaaaggcg
     2581 caatgttgga tgtttttaat cgtgaaccct taccgcctga aagtccgctc tggcaacatc
     2641 cacgcgtgac gataacacca catgtcgccg cgattacccg tcccgctgaa gctgtggagt
     2701 acatttctcg caccattgcc cagctcgaaa aaggggagag ggtctgcggg caagtcgacc
     2761 gcgcacgcgg ctactaataa agcatcagga ttcctgctat ccttggcggg aattgaatac
     2821 aggagagagt tatgtatccc gtcgaccttc atatgcatac cgttgccagc acacatgcat
     2881 atagcacatt gagtgattac attgcccagg ccaaacaaaa gggcattaaa ctttttgcga
     2941 tcaccgatca tggcccggat atggaagatg ctccgcatca ctggcacttc attaacatgc
     3001 gtatctggcc gcgagtggtt gatggggtag ggatcctgcg cggcatcgaa gctaacatta
     3061 aaaatgttga tggtgaaatt gattgcagcg gtaaaatgtt tgactcgctg gatctgatta
     3121 ttgccggttt tcatgagccg gtttttgcac cacatgacaa agcgaccaat acacaagcga
     3181 tgatcgccac tatcgccagc ggcaatgtgc atataataag ccatcccgga aatcccaaat
     3241 atgaaataga tgtgaaagcc gttgctgaag cagccgcgaa acatcaggtg gcgctggaaa
     3301 tcaataattc ttcattttta cactcacgta agggcagtga agacaactgt cgtgcggtag
     3361 ccgcagcggt acgtgatgct ggaggttggg tggcattagg ctcggattct cacaccgcgt
     3421 ttaccatggg ggaatttgaa gagtgtctta aaatcctcga cgcggtagat tttccgccag
     3481 agcgcatttt gaatgtttct ccgcgccgct tactgaactt ccttgaatct cgcggtatgg
     3541 caccgattgc ggaatttgca gacctttaat tactagtaat ggaaatatat taatgaacga
     3601 gttttctatc ctctgtcgtg tgctgggttc gctctattac cgccaaccgc aagatccttt
     3661 actggtgccg ctgtttaccc tgattcgtga ggggaaactg gctgcgaact ggccactgga
     3721 gcaggatgag ttactgacgc gtttacagaa aagctgtgat atggcgcaag tctctgccga
     3781 ttacaatgcg ttgtttatcg gcgatgaatg tgccgtgccg ccatatcgta gcgcatgggt
     3841 tgaggatgca acggaagcgg aagtgcgcgc ttttctttcc gaacgaggga tgccactggc
     3901 ggatacgcca gccgatcaca tcggcacatt gctgcttgcg gcttcctggc tggaagatca
     3961 gtcaacggaa gatgagagcg aagcactgga aacactgttc agtgagtatc tgttaccctg
     4021 gtgtggtgcg ttcctcggca aagtggaggc ccatgcaacc acgcctttct ggcgcaccat
     4081 ggcaccgcta acccgtgatg ccattagtgc aatgtgggac gagctggaag aagattctga
     4141 agagtaaatg tgatcatcgt cactcataac tgcaacagat aatttgttgt tgcataaaat
     4201 gtgtgctcga tctcattcat ggccgcgttt tctgctatca tgcgcggcat gaacatactt
     4261 ctctctattg caatcacaac aggcattctc tccggtatct ggggatgggt ggctgtttcc
     4321 ctgggcttac taagctgggc gggcttcctg ggctgtacgg cctactttgc ctgcccgcaa
     4381 ggtgggctga aagggctggc gatctccgct gcaaccctgc ttagtggcgt ggtgtgggcg
     4441 atggtcatta tttacggtag tgcactggca ccacatctgg aaattctcgg ttatgtcata
     4501 accggtattg tcgcgtttct gatgtgtatt caggccaaac agctgctgct ttcatttgtt
     4561 ccggggacgt ttataggcgc atgcgcgacg tttgccgggc agggtgactg gaaactggtg
     4621 ttaccttcgc tggcgcttgg gctggtattt ggttacgcaa tgaaaaacag cggcctgtgg
     4681 ctggcggcgc gtagtgcaaa gacggctcac cgtgagcagg aaatcaaaaa taaagcgtga
     4741 ggggcactca cgctttcgct taaacagtaa aatgccggat gataattccg gcttttttat
     4801 ctgtcaggat tccggtggaa ccgacatatg gcggtatttc accagaatgt cgttctgccg
     4861 ttctgctttg ttctgcaaat cccacagacc acggtcgata ccatcattaa tcaggaaaat
     4921 gacccctgtt tcgatagccg acatcagaca cagcataacg ggttcgtttg aggtgtaacc
     4981 cacttcccct tccagcaagc gctggtagtc aataaagcgg aaaaccccgg cctgaacttc
     5041 ataggaaagt atcgtcttac tggtgttcac cgaggagagg atctcaccgg tactcacatt
     5101 gacgacgcgc aggttcacgg caatctgatc gagctggtat tgcgtgtctg caccgatccc
     5161 aaaatatctt gccccaacac cgcccgattt aacgttgctt tcataaccga taatcgaacc
     5221 ttcaaccata atatttgccg ccgttaaaga ttgcagcggg attcggttat taatggcaac
     5281 cgtgccgttt tcttgtgccg cacgaataat cttgcgctcg ttaagcaggt tttgtaagcc
     5341 ctggcgctcc agcggtataa accagcgaga atctttcaat gccgtgacca gcattgccgt
     5401 ggcgctttgc ggaacagcag tggagaagtt acttgccggg tagggtttaa attgcccggt
     5461 ttcgtcctga atgttgtata ccgaaacaaa gatcttaccc gtcggcgctg gcagatgggt
     5521 caaatctttg tagctctgag ctcgaggcat taatgtcggt ctggcggctt ctttaggcgg
     5581 ggcggttaag catccgctca gtaacatgac ggcaaccaaa agaaataagc gctgcatgat
     5641 tattttcctt atgaagctgg ggcttaaaaa tcggttgagt tattttgtaa acccgaaacc
     5701 tggatggtcg aggtttgtcc ggttttacga tctgtcacgt tcaactgcaa ttgaccatcg
     5761 cggttagcaa tatcaacaat ataatcgttg gtcaccatgc ggcccggttt accggtatta
     5821 atattcgaca gtagcccacc taaaatttgt gactggatgg cctgagtaaa gttatctaac
     5881 gctgagggtg tttcaatacc aaagtcatcg ttatagctcg gatctttata agagttttgg
     5941 gcctgagcgc tatttaataa aaaagcgcca ttatttgggt taccaccaaa gtttggatta
     6001 cggaactgga aagtcatggt tccagcccaa cttaatggcg aaataagcat gagtagaact
     6061 actgcatgtt tgacacgcat tgcagcctcc gaacaatttt ttatttagaa ttcatcatgc
     6121 gccaaatcgc ccgtacttaa taacgcctga tttatctggc gacgatttag tgcttcttca
     6181 gtttgaatca gtgcaaagac gacagttttc tcgaagtctc ttttcaacgg aaataaaaaa
     6241 gtctggaaaa taacgtcctg attgaccgtt atagtgatcc agcttcccca tcgtgcactg
     6301 ggcctttcat taatcgttaa gttacccgta tagtcacttt cccatttatc actaaaggct
     6361 cggtaaaaat catggccaat agatgaaaca gtatggtcag ttaacaatcc cgggacttct
     6421 acctcaacgg cgtgaagatt ccctgcggcg aacagaaatt ctgccgccac aatccagcgt
     6481 aaataacgtt tcatggcttt atcgcctgag gttatcgttt gcccaggaaa ccgcttgtgt
     6541 ccggtttttt acggctatct tcttgaaaag attataaaga tgcgttttaa ccgtattttc
     6601 gctgatgaac aacgaacgag cgatctcgtt attagacgcg ccgatacgca gcttattcag
     6661 gatctctttt tcccgatgag taaggagggc tgattccgtg ctgttataac gatagttacc
     6721 agaatgtgta atcaggtaac tggcaagctt ttgcgtaaag tagcattcgc cgcgcaggac
     6781 gccttgcaac ccattgacaa cacgttcttg atcctccatg gcataaaaaa cgccgttgat
     6841 atgaggccag ttttcaatgt cgcggtacgg gtaatcttca ggcgtattta gcaacaatat
     6901 tttgatattg ttgtttttcc tgctcaaagt atcctgccaa taatggataa gctttttatc
     6961 tgcttccatc atatccagaa gaataataga gcctgaagat atatcgtcca gagaacgttg
     7021 aatattatgt aattttcctg taattgccag cgattgttta aggtgctgca agagagctgt
     7081 cgcttgcaaa gacggtttag tgatcaacaa taatgtatga ccatgaatac tatggacttc
     7141 attaaacatg atgaaacccc gcttttttta ttgatcgcac acctgacagc tgcctctaaa
     7201 atagaagcac cagaagtact gacagatgtt gcactgctgt gtgtagtaat
//
LOCUS       DAPGUL010000181         7245 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.185, whole genome shotgun sequence.
ACCESSION   DAPGUL010000181 DAPGUL010000000
VERSION     DAPGUL010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7245
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.185"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(306..1442)
                     /locus_tag="RHX21_004412"
     CDS             complement(306..1442)
                     /locus_tag="RHX21_004412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HDV1989503.1"
                     /translation="MDLLIVLTYVALAWAVFKIFRIPVNQWTLATAALGGVFLVSGLI
                     LLMNYNHPYTFTAQKAVIAIPITPQVTGIVTEVTDKNNQLIQKGEVLFKLDPVRYQAR
                     VDRLQADLMTATHNIKTLRAQLTEAQANTTQVSAERDRLFKNYQRYLKGSQAAVNPFS
                     ERDIDDARQNFLAQDALVKGSVAEQAQIQSQLDSMVNGEQSQIVSLRAQLTEAKYNLE
                     QTVIRAPSNGYVTQVLIRPGTYAAALPLRPVMVFIPEQKRQIVAQFRQNSLLRLKPGD
                     DAEVVFNALPGQVFHGKLTSILPVVPGGSYQAQGVLQSLTVVPGTDGVLGTIELDPND
                     DIDALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWMHYLYLDH"
     gene            complement(1445..1807)
                     /locus_tag="RHX21_004413"
     CDS             complement(1445..1807)
                     /locus_tag="RHX21_004413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3302 domain-containing protein"
                     /protein_id="HDV1989504.1"
                     /translation="MFLNYFALGVLIFVFLVIFYGIIAIHDIPYLIAKKRNHPHADAI
                     HTAGWVSLFTLHVIWPFLWIWATLYQPERGWGMQSHVASQEKATDPEIASLSDRISRL
                     EHQLAAEKKTDYSTFPEI"
     gene            2344..4257
                     /gene="mtlA"
                     /locus_tag="RHX21_004414"
     CDS             2344..4257
                     /gene="mtlA"
                     /locus_tag="RHX21_004414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HDV1989505.1"
                     /translation="MSSDIKIKVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLP
                     NETLAKLVGPMITYLLPLLIGYTGGKLVGGERGGVVGAITTMGVIVGADMPMFLGSMI
                     AGPLGGWCIKHFDRWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPIVEALSKM
                     LAAGVNFMVVHDMLPLASIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSIFFLIE
                     ANPGPGMGVLLAYMFFGRGSAKQSAGGAAIIHFLGGIHEIYFPYVLMNPRLILAVILG
                     GMTGVFTLTILGGGLVSPASPGSILAVLAMTPKGAYFANIAGVCAAMAVSFVVSAILL
                     KTSKVKEEDDIEAATRRMQDMKAESKGASPLSAGDVTNDLSHVRKIIVACDAGMGSSA
                     MGAGVLRKKIQDAGLSQISVTNSAINNLPPDVDLVITHRDLTERAMRQVPQAQHISLT
                     NFLDSGLYTSLTERLVAAQRHTANEEKVKDSLKDSFDDSSANLFKLGAENIFLGRKAA
                     TKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTPTYLGESIAVPHGTVEAKDRVLKT
                     GVVFCQYPEGVRFGEEEDDIARLVIGIAARNNEHIQVITSLTNALDDESVIERLAHTT
                     SVDEVLELLAGRK"
     gene            4487..5635
                     /gene="mtlD"
                     /locus_tag="RHX21_004415"
     CDS             4487..5635
                     /gene="mtlD"
                     /locus_tag="RHX21_004415"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709374.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDV1989506.1"
                     /translation="MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARH
                     SYQVHVVGETEQVDTVSGVNAVSSIGDDVVDLIAQVDLVTTAVGPVVLERIAPAIAKG
                     LVKRKEQGNESPLNIIACENMVRGTTQLKGHVMNALPEDAKAWVEEHVGFVDSAVDRI
                     VPPSASATNDPLEVTVETFSEWIVDKTQFKGALPNIPGMELTDNLMAFVERKLFTLNT
                     GHAITAYLGKLAGHQTIRDAILDEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIQK
                     ILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYSLPHKNLIQGIAGAMHF
                     RSEDDPQAQELAALIADKGPQAALAQISGLDANSEVVSEAVTAYKAMQ"
     gene            5635..6222
                     /gene="mtlR"
                     /locus_tag="RHX21_004416"
     CDS             5635..6222
                     /gene="mtlR"
                     /locus_tag="RHX21_004416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol operon repressor MtlR"
                     /protein_id="HDV1989507.1"
                     /translation="MVDQAQDTLRPNNRLSDMQATMEQTQAFENRVLERLNAGKTVRS
                     FLITAVELLTEAVNLLVLQVFRKDDYAVKYAVEPLLDGDGPLGDLSVRLKLIYGLGVI
                     NRQEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCVAALPPPPQFEPADSSL
                     YAMQIQRYQQAVRSTMVLSLTELISRISLKKAFQK"
     gene            complement(6234..6443)
                     /locus_tag="RHX21_004417"
     CDS             complement(6234..6443)
                     /locus_tag="RHX21_004417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989508.1"
                     /translation="MGKLGENVPLLIDKAVDFMASSQAFREYLKKLPPRNAIPSGIPD
                     ESVPLYLQRLEYYRRLYRPKQVEGQ"
     gene            6728..7090
                     /locus_tag="RHX21_004418"
     CDS             6728..7090
                     /locus_tag="RHX21_004418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibL family ribosome-associated protein"
                     /protein_id="HDV1989509.1"
                     /translation="MKEVEKNEIKRLSDRLDAIRHQQADLSLVEAADKYAELEKEKAT
                     LEAEIARLREVHSQKLSKEAQKLMKMPFQRAITKKEQADMGKLKKSVRGLVVVHPMTA
                     LGREMGLQEMTGFSKTAF"
BASE COUNT         1832 a         1822 c         1842 g         1749 t
ORIGIN      
        1 ttttaaatgt gactgtcatc cttcagataa taaagccatc atcgcaatag atggaaaagc
       61 actcctgctc ttttttgatt agagccgtcg caggaggaac aactcatatc atcattgcga
      121 tctcgacgat gtatagtctc atcctgcggc agaacaagac ggataaaaaa tccaatgaga
      181 gcacactcat ccagaactta ttaacataat gaatattaaa gaaaaatcat cgcagctaat
      241 gaagtaatat gcaaaaataa ttagtcctta caaggagcaa agttccataa tctcccccct
      301 ccccctcaat gatccaaata aagataatgc atccagctgg tcattcttag cagcactttc
      361 cgcatcaccg aaacatggct gaaatggtcg gagtaaaccg ccacctgggc gtagatgccg
      421 tcgggtaagg catcgatatc atcgttagga tccagttcaa tggttcccag cacaccgtcc
      481 gtgccgggca cgaccgttaa tgattgcaat accccctgcg cctgataaga accgcctggc
      541 acgacaggta aaatactagt cagtttgccg tgaaacacct gcccaggtag cgcgttaaac
      601 accacttccg catcatcgcc gggtttcaga cgtaacagcg agttttgccg aaattgggcg
      661 acaatttgcc gtttttgctc ggggatgaag accatcaccg gacgcagcgg caaggcagct
      721 gcgtatgtac ctgggcggat cagtacctga gtaacgtagc cattgctcgg cgcgcgaatg
      781 acagtctgct caaggttata ttttgcttca gtaagttgcg ctcttaagct cacaatctgc
      841 gattgctcgc cgttaaccat actgtcgagc tggctctgga tctgcgcctg ctccgccacc
      901 gagcctttca ccagcgcatc ctgcgcgagg aaattttgcc gcgcatcgtc gatgtcacgt
      961 tccgagaacg gattcaccgc cgcctggctg cctttcaagt aacgttgata atttttaaac
     1021 agacggtcgc gctccgctga aacctgggtg gtgttggcct gcgcttcagt gagctgcgca
     1081 cgcagcgtct ttatattatg cgtcgccgtc atcaggtcag cctgaagtct gtcaactcgc
     1141 gcctggtaac gaaccgggtc gagcttaaaa agcacctcgc ccttttgaat aagctgatta
     1201 ttcttgtcag tgacttcagt aacaattccc gtcacctgtg gcgtgatagg gatcgctatc
     1261 actgcctttt gcgcggtaaa agtgtaaggg tggttgtagt tcatcaacaa aatcaaacca
     1321 ctcaccagaa acacgcctcc cagcgccgcc gtcgccagcg tccactgatt taccggaatg
     1381 cggaagattt taaagaccgc ccacgccagc gccacgtaag ttaaaacaat caatagatcc
     1441 ataattagat ctccgggaac gtggaatagt cagtcttttt ctcggcggcg agttgatgct
     1501 ccagccggga aattcggtca gaaagtgagg cgatttccgg gtcagttgct ttctcctgcg
     1561 acgcaacatg tgactgcata ccccagccac gctccggttg atagagcgtc gcccagatcc
     1621 acagaaacgg ccagataaca tgcagagtaa acaggctcac ccagcccgcc gtatgaatag
     1681 cgtcggcatg ggggtgattg cgctttttgg caatcagata agggatgtca tgtatcgcga
     1741 tgattccata aaaaatcacc agaaagacga agatcagcac tcccaacgcg aaatagttta
     1801 gaaacatatc tgcctcggat tcacgtttat cagtgttgtt tttgggctgg cagccagaag
     1861 ggagtcaggc tgatattttg acaataatcc gggttcgcga ttctcgccat aacaccaaag
     1921 aataattttt agaggtgatg agttgcttag ttacataacg attgtatgac gaaggcataa
     1981 catgctgtag atcacatcag gtgaacgccg taagaaaata tcttgtgatt cagatcacaa
     2041 agattcaaca aaccatcaaa acaaaaatgt gacactactc acatttaaat gccattttta
     2101 gcgaaaatcg ccgtcttgtt gcttttttac acaagcgttt tgtgatgagt atcacgtcaa
     2161 ttacctctct accccctata tttatgtgac tgatatcaca caaaaggccg tcgactggac
     2221 agttaaccga ttcagtgcca gatttcgcag tatctacaag gtccggctac ctctgccgcc
     2281 acattaacaa aaaacctcgg gcttccagcc tgcgcgacag caaacataag aaggggtgtt
     2341 tttatgtcat ccgatattaa gatcaaagtg caaagctttg gtcgtttcct cagcaacatg
     2401 gtgatgccaa atatcggcgc gtttatcgcg tggggtatca tcaccgcgtt atttattcca
     2461 acagggtggt taccgaacga gacgctggcg aagctggtcg ggccgatgat cacttatctc
     2521 ctgccgctgc tgatcggtta taccggtggt aagctggtag gcggcgaacg tggcggcgta
     2581 gtcggtgcca tcactaccat gggcgttatc gtcggcgcag acatgccgat gttcctcggt
     2641 tctatgattg caggtccgct gggcggctgg tgcattaagc acttcgaccg ctgggtagac
     2701 ggtaagatca aatccggttt tgagatgctg gtgaataact tctccgcagg catcatcggg
     2761 atgatcctcg ccattctggc atttctcggc attggcccga ttgttgaagc cctgtccaaa
     2821 atgctggctg cgggcgttaa cttcatggtt gtccatgaca tgctgccgct ggcgtctatc
     2881 tttgttgaac cggcgaaaat cctgttcctc aacaacgcca ttaaccacgg tatcttctcg
     2941 ccgctgggta ttcagcagtc ccatgaactg ggtaaatcca tcttcttcct gattgaagct
     3001 aacccaggtc caggtatggg cgtgctgctg gcgtacatgt tctttggtcg tggtagtgct
     3061 aaacagtctg cgggcggtgc ggcaatcatc cacttcctgg gtggtatcca cgaaatctac
     3121 ttcccgtatg tgctgatgaa tccgcgtctg atcctggccg ttatcctcgg cggtatgact
     3181 ggcgtgttca cgctgactat cctgggcggt ggtctggttt ctccagcatc tccggggtct
     3241 atccttgcgg tactggcgat gacgccaaaa ggtgcttact tcgctaacat cgcgggtgtg
     3301 tgtgcggcga tggctgtctc cttcgttgtc tctgctattt tgctgaaaac cagcaaagtg
     3361 aaagaagaag atgatattga agcagcaact cgtcgtatgc aggacatgaa agctgagtct
     3421 aaaggcgcat ctccgctgtc tgctggcgat gtgactaacg acctgagcca cgtacgtaaa
     3481 atcatcgttg cctgtgacgc cggtatgggt tccagtgcga tgggcgcagg cgttctgcgt
     3541 aagaaaattc aggatgcagg tctgtcgcag atttctgtta ctaacagcgc gatcaacaac
     3601 ctgccgccag atgtggacct cgtcatcact caccgtgacc tgaccgaacg cgctatgcgc
     3661 caggttccgc aggcacagca tatttcgctg accaacttcc tcgacagcgg cctgtacacc
     3721 agcctgaccg aacgtctggt tgctgcccaa cgccacacgg caaacgaaga gaaagtaaaa
     3781 gacagcctga aagacagctt tgacgattcc agtgctaacc tgttcaagct aggcgcggag
     3841 aacatcttcc tcggtcgcaa agcggcaacc aaagaagaag cgattcgttt tgctggcgag
     3901 cagctggtga aaggcggtta cgttgagccg gaatacgttc aggcgatgct ggatcgtgaa
     3961 aaactgaccc cgacttatct gggtgagtct atcgcggtgc cacacggtac ggttgaagcg
     4021 aaagatcgcg tactgaaaac gggcgtggtg ttctgccagt acccggaagg cgtgcgcttc
     4081 ggtgaagaag aagatgacat tgcccgtctg gtgattggta ttgcagcccg taacaacgag
     4141 cacattcagg ttatcaccag cctgaccaat gcactggatg atgagtccgt catcgagcgt
     4201 ctggcacaca ccaccagcgt ggatgaagtg ctggaactgt tggcaggtcg taagtaatcc
     4261 aatcccaccc tctccacatg gagaaggtgg ggttaattgc ctgatgcgct acgcttatca
     4321 ggcctacagg atgcatcacg atttgttgaa tttgcacgtt cttgtaggcc ggataaggcg
     4381 cttacgccgc atccggcgct gcccctctcc tcacggagag ggtttgggtg agggaaaagc
     4441 ctcaccccag ccctctcggg taaaaacatt gatgaaggtt aatactatga aagcattaca
     4501 ttttggcgca ggtaatatcg gtcgtggctt tatcggtaaa ctgctggcag acgcgggtat
     4561 ccaactgacg tttgccgatg tcaatcaggt ggtacttgat gccctgaatg cccgtcatag
     4621 ctatcaggtt catgtggttg gtgaaaccga gcaggtagat accgtttccg gcgtcaatgc
     4681 tgtcagcagc attggtgatg atgtcgttga tctgattgct caggtcgatt tagtcactac
     4741 cgccgttggc ccggttgtgc tggaacgtat tgctccggct atcgccaaag ggctggtgaa
     4801 acgcaaagaa caaggtaatg aatccccgtt gaacatcatc gcctgtgaaa acatggtacg
     4861 cggtaccacg cagctgaaag gccatgtgat gaacgccctg ccggaagacg ccaaagcgtg
     4921 ggtagaagaa cacgttggct ttgtcgattc cgccgttgac cgcatcgtac cgccttcggc
     4981 ttcggcaact aacgatccgc tggaagtgac ggtagaaact ttcagcgaat ggattgtcga
     5041 taaaacgcag ttcaaaggcg cactgccgaa catcccaggc atggagttaa ccgacaacct
     5101 gatggcattt gtcgaacgta aactcttcac cctgaacacg ggtcatgcta taaccgcgta
     5161 cctcggaaaa ctggccggtc atcagaccat tcgtgacgct attctcgacg agaaaatccg
     5221 cgcggtggta aaaggtgcga tggaagaaag tggtgcggta ctgatcaagc gctacggctt
     5281 tgacgcagac aaacatgcgg cgtacatcca gaaaatcctc ggtcgttttg agaacccgta
     5341 tctgaaagat gatgtagagc gcgtaggccg tcagccgctg cgtaaactga gtgctggcga
     5401 ccgtctgatc aagccattgc tcggtacgct ggaatacagc cttccgcaca agaatctgat
     5461 tcaggggatt gctggtgcaa tgcacttccg cagtgaagat gatccgcagg ctcaggaact
     5521 ggcagcactg atcgctgaca aaggtccgca ggcggcgctg gcacagattt ccggtcttga
     5581 tgccaacagc gaggttgtat ccgaggcggt aaccgcttat aaagcaatgc aataatggtg
     5641 gaccaggcgc aggacaccct gcgcccgaat aacagattgt cagatatgca ggcaacaatg
     5701 gaacaaaccc aggcctttga aaaccgtgtg cttgagcgtc tgaatgctgg caaaaccgtg
     5761 cgaagctttc tgatcaccgc cgtcgagctt ttgaccgagg cggtaaatct tctggtgctt
     5821 caggtattcc gcaaagacga ttacgcggtg aagtatgctg tagaaccgtt actcgacggc
     5881 gacggtccgc tgggcgatct ttctgtgcgt ttaaaactca tttacgggtt gggcgtcatt
     5941 aaccgccagg aatacgaaga tgcggagctg ctgatggcat tgcgtgaaga actaaatcac
     6001 gacggcaacg agtacgcctt taccgacgac gagatccttg gaccctttgg tgaactgcac
     6061 tgcgtggcgg cgttaccacc gccgccacag tttgaaccag cagactccag tttgtatgca
     6121 atgcaaattc agcgctatca acaggctgtg cgatcaacaa tggtcctttc actgactgag
     6181 ctgatttcca gaatcagctt aaaaaaagcc tttcaaaagt aagcaacgtc tgcttactgc
     6241 ccctctacct gcttcggccg ataaagccga cgataatact ccagacgttg tagatataac
     6301 ggcacgcttt catcgggtat tccggacgga atcgcgttac ggggaggaag ttttttcaga
     6361 tactcccgga acgcctggct tgatgccatg aaatctacgg ctttatcgat aagaagcgga
     6421 acgttttcac ctaatttgcc catgatgata tctccgtatt accccgcgcc gggaatgcgc
     6481 ggccgccaat tttagtttag gttcccggta aagatgacat taaggaaaac gtgctgaatc
     6541 ctcaataatc atccgctgct gtttattatc ttttttctat agatttctta attaatcaat
     6601 aaattgcgta gtttttaagc atgttaatga ttacgttaca gaactattgc aatgtcatca
     6661 gttgtgaaca aagcacctgg tcgcgcatac taggggctat aaatttatct ttatcagaag
     6721 ccatcacatg aaagaagtcg aaaaaaacga aatcaaacgt ctcagcgatc gtctggacgc
     6781 catccgccac cagcaggccg atctgtcgct ggttgaagcc gcagacaaat atgccgagct
     6841 ggaaaaagag aaagccacgc tggaagcaga aattgctcgc ctgcgtgaag ttcatagcca
     6901 aaaactgagt aaagaagcac agaagctgat gaagatgccg tttcagcgcg caattaccaa
     6961 aaaagagcag gctgatatgg gcaagctgaa gaaaagtgtt cgcggactgg tggttgtgca
     7021 cccaatgacc gcgctgggcc gtgaaatggg cctgcaggag atgactggat tctctaagac
     7081 tgcgttttaa gcgcctcaga cgactggttc gatcatatca acccgcatct ggcttgcctt
     7141 agctggtcaa tgcggggact ctcctgtcta ctcgcctaat taccaaacaa ttcactccct
     7201 ttacttcgat ttaccgctgg ttgatattct gaaaatgcat tttta
//
LOCUS       DAPGUL010000182         7208 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.186, whole genome shotgun sequence.
ACCESSION   DAPGUL010000182 DAPGUL010000000
VERSION     DAPGUL010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7208
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.186"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..448
                     /locus_tag="RHX21_004419"
     CDS             <1..448
                     /locus_tag="RHX21_004419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="inovirus Gp2 family protein"
                     /protein_id="HDV1989510.1"
                     /translation="ATDAAVISRFINALKARIDAYQKRKHREGKRVHPTTLHYVWARE
                     FGECKGKKHYHLMLLVNRDTWCRAGDYRAPESLAGMIKQAWCSALGVDVGCHATLVHF
                     PAWPAVWLARNDDTGFQQVLERADYLAKEYTKAHCTGERNFGCSRS"
     gene            708..1109
                     /locus_tag="RHX21_004420"
     CDS             708..1109
                     /locus_tag="RHX21_004420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004020115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989511.1"
                     /translation="MYAKSFIALDGNGRLTGARTAQAAPYAHYTCHLCGSALRYHPQY
                     DTELPWFEHTDDRLTEHGQQCPYVRPERREIQLIKRLQQFVPDALPVVRKASWHCRQC
                     HHDYYGERYCTHCQTGGFSIPRTTQEEICEF"
     gene            1097..1507
                     /locus_tag="RHX21_004421"
     CDS             1097..1507
                     /locus_tag="RHX21_004421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HDV1989512.1"
                     /translation="MRILNCYMANDSKGHFVTAKEAAKHNRQDVLCCVSCGCPLTLQR
                     GNDGQPPWFEHDQMTVAEKILLRCTWLDPAEKEARRLHLQGMTVPDYTVKVRKWFCVM
                     CDEDYEGEKCCPRCGTGVYSREGGLQEGNWKDRN"
     gene            1791..3410
                     /locus_tag="RHX21_004422"
                     /pseudo
     CDS             1791..3410
                     /locus_tag="RHX21_004422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001368704.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            3490..3782
                     /locus_tag="RHX21_004423"
                     /pseudo
     CDS             3490..3782
                     /locus_tag="RHX21_004423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312320.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
     gene            complement(3822..4856)
                     /locus_tag="RHX21_004424"
     CDS             complement(3822..4856)
                     /locus_tag="RHX21_004424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotriesterase"
                     /protein_id="HDV1989513.1"
                     /translation="MKDYLQTVTGPVAREDMGLTLPHEHLFNDLSSVVDAPCYPFSQR
                     LVDKKVTAEIQWALKHDPYCCADNMDRKPIEDVIFEINNFISLGGRTIIDATGSESIG
                     RDAQALREVALKTGLNIVASSGPYLEKFESQRIHKTVDELATTIDKELNQGIGDTDIR
                     AGMIGEIGVSPTFTEAEHNSLRAASLAQINNPHVAMNIHMPGWLRRGDEVLDIVLGEM
                     GVSPNKVSLAHSDPSGKDVAYQRKMLDKGVWLEFDMIGLDITFPKEGIAPGVQETADA
                     VAHLIELGYADQLVLSHDVFLKQMWAKNGGNGWGFVPDVFLAYLAERGVDKTILKKLC
                     IDNPGRLLTA"
     gene            complement(4859..5824)
                     /locus_tag="RHX21_004425"
                     /pseudo
     CDS             complement(4859..5824)
                     /locus_tag="RHX21_004425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462450.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
     gene            complement(5881..6639)
                     /locus_tag="RHX21_004426"
     CDS             complement(5881..6639)
                     /locus_tag="RHX21_004426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HDV1989514.1"
                     /translation="MNNTKKSLKVLFIGESWHIHMIHSKGYDSFTSSKYEEGATWLLQ
                     CLKNSQVDVTYMPAHTVQIAFPEDVAQLEQYDAIVISDIGSNTFLLQNDTFYQLRIKP
                     NALELIKEYVNNGGGLLMIGGYLSFMGIEAKANYKNTVLADVLPVTMLDGDDRVEKPE
                     GVIAQPSQPEHPVIKGFSEYPFFLGYNRAIAKENAEVVLTINNAPLLVFGNYHNGKIA
                     CFMSDCSPHWGTQQFMSWPFYTALWVNILTHIAR"
     gene            complement(6653..7012)
                     /locus_tag="RHX21_004427"
                     /pseudo
     CDS             complement(6653..7012)
                     /locus_tag="RHX21_004427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462448.3"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
     gene            7075..>7208
                     /locus_tag="RHX21_004428"
     CDS             7075..>7208
                     /locus_tag="RHX21_004428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDV1989515.1"
                     /translation="MTKTVSTSKKPRKQHSPEFRSEALKLAERIGVTAAARELSLYES
                     "
BASE COUNT         1889 a         1723 c         1803 g         1793 t
ORIGIN      
        1 agcaacggac gcagctgtga tatcccgctt catcaatgcc ctgaaagccc gaatcgacgc
       61 ttaccagaaa cgtaagcatc gggaaggtaa acgcgtgcat cccacaaccc tgcattacgt
      121 ctgggcccgg gagtttgggg agtgcaaagg taaaaaacac tatcacctga tgctgctggt
      181 caaccgggat acctggtgtc gtgccggtga ttaccgcgct ccggagtctc tggccgggat
      241 gattaaacag gcgtggtgca gtgccctggg agtggatgtc gggtgccatg ccacgctggt
      301 gcattttccg gcctggccgg cggtgtggct ggcgcgtaat gatgacaccg gctttcagca
      361 agtgctggaa cgtgctgact atctggcgaa ggagtatacc aaagctcact gcaccggtga
      421 gcgcaatttt ggctgtagcc ggagttgagc acgactggcg cgccaatatc cggcaaacca
      481 aaagtatggg ttgttgtctg gcggcaacga tgtatccact cgcccactga ctgtttttta
      541 cgtcagtgtt ccattgtgtg acaaccacag tgctgtaaca gcaaccagcc tgctttaccc
      601 aaactccagt ccagatttta actgaaccgc cattcacacc ctgaccacgc tgcccgtacc
      661 gggacggttg ttgcctgcgt gtcgtctggc ggctaaggaa tatgactatg tacgcaaaat
      721 cctttatcgc tcttgatggc aacggacgtc tgacgggcgc ccgtactgca caggccgcac
      781 cttatgctca ctacacctgc cacttgtgtg gcagtgcact cagataccat ccgcaatacg
      841 acactgaact tccctggttt gaacacactg acgacaggct gacagagcac ggtcaacagt
      901 gcccttatgt caggccggag cgcagagaaa tacagttgat taaacgtctg cagcaattcg
      961 taccggatgc cttacccgtg gtgcgtaaag ccagctggca ctgcagacaa tgtcaccacg
     1021 attattatgg ggagcggtac tgcacacact gccagaccgg aggattcagt attccccgga
     1081 caactcagga ggaaatatgc gaattctgaa ctgttatatg gcgaatgaca gcaaaggcca
     1141 ttttgttacg gcgaaagaag cagcgaagca caaccgccag gacgttttgt gctgtgtgtc
     1201 ctgtggatgc ccgttaacac ttcagcgggg caatgacgga caaccaccgt ggtttgaaca
     1261 tgaccagatg actgtcgctg agaaaatcct gctgcgatgc acctggcttg acccggcaga
     1321 gaaagaggcc cgtcgtttgc atctgcaggg tatgacggtt ccggattata cggtgaaggt
     1381 gagaaagtgg ttttgtgtga tgtgtgacga agattatgaa ggagaaaagt gctgcccgcg
     1441 ttgtggtacc ggggtataca gcagggaggg ggggctgcag gaaggcaact ggaaggatag
     1501 gaactgagcg gttcagtcgc ggaaatcagt tgcagagctg taatgatatc tccgggagtg
     1561 ctgcgttggt aggggcatcc cgggatagag aaattttagc actttgccct gaatgattgt
     1621 agacgttccg agtactcgta ccggtctgag ttattacagt tagatattca ctttttctcc
     1681 cgcatacttc acatctgtca acgacggatg aaaagtggtt cttccgcaac ctgggtggaa
     1741 gaaaatggat gaaactttct ggcgaacaag gatctaagct gttttaagtt atgggcaacg
     1801 caatgcactc tcttaagaca cttctacagt taccttgcgg atggcgatgc agtcgacaaa
     1861 ttattagctc tgacggtata accctccatc tccacggaaa acgcaaaaca gcacaatgtc
     1921 ctgaatgctt taagcgtagc gactctgttc atagttgtcg tcggcgccgg atacagcatc
     1981 taccctgctc agggcagacg ctatggcttg tattttccgt ccgccactgg tactgccgta
     2041 acccggcttg ttcacgtaaa atttttgccg agtcgcttgc tcccttcgcc ggttcacacc
     2101 agcagtcttc acaggcgtta caaaatttac aacgtcaact gggattaata gctggaggtg
     2161 aggctggaaa acgggctgca acggcagcgg gtctccgttg cagtgctgat actcttcttc
     2221 gcagggttat caataccccg gagacgaaac agtcaggcgc gcctcatgtc ggtattgatg
     2281 agtgggcgtg gcatcggggc cactgctgcg gtatgttaat agtcaatctt gatactcacc
     2341 gtcccctcgt cctgcttccc ggccgtgatc agcgtacgct ggcgacctgg ttcagaaaat
     2401 atccggaaat acaggttgtc tcgcgtgatc gcagtggagt ctatgcgaca gcagcacgtg
     2461 aaggtgcacc tcaggccaga caggtggccg atcgatggca cctgctaaaa aatattggtg
     2521 atgagcctga acgaatgatg tacagacata tgcctctgat acgtcttgtt gtcagagagt
     2581 tatcactgaa gaaatcacct gagccagaaa tatctgtgcc tgtagcatcg ctccgtcgtc
     2641 tggaacgcct taaacagcac atccgcaaaa aacggcatca gcgttggaca gaggttatgg
     2701 ccctgcataa caagggatgt agtttcaggg aaatatcccg tattacaggc ctgtcgcgag
     2761 tgacagtcag tcgctgggtg ggttcaggaa cattccctga aatgtcaact aggcctccaa
     2821 agcgagggct tctggaccca tggagggagt ggttaaaaga gcaacgagaa tgtggtaatt
     2881 ataactccgg ccggatatgg cgggaaatgg tggccagggg ggttacaggc agtgaaacca
     2941 tcgtcaggga tgctgttgcc aaatggcgta aaggctggat cccaccggtt actactgccg
     3001 caagacttcc ttcagtgtcc cgggtaagcc gctggttgat gccctggaga ataatcaggg
     3061 gtgaagaaaa ttatgctttc cgatttatta gtctgatgtg tgaaaaagaa ccggagttga
     3121 aaatagcgca gcaactggta ctcgagttct accgtattct gaaaacctaa aataaatcac
     3181 agctaagcag ctggttcacc cgggtccacg aaagcggctc agcagaactt cggtgcgtag
     3241 ctgcggggat ggaagctgat gctgcggcta tatgtgaggc aatcagcagt cgctggagta
     3301 ctggtgttgt cgaaggtcat gtaaatcgcc tgaaggtgct gatacgccag atgtatggtc
     3361 gagccggact tgaactactt aggaggaggg taatgagtcc actggcatga aaatcttcac
     3421 ccaggttgcg gaagagccac ttttgcactg ttcgtgacag tatggccttt atgtactcac
     3481 tttgttaccg gtagctggat catcactacc gtgctgcaaa tggtggtgaa cagcatcaat
     3541 tgtggaatga atgttgccga agcgaccaat gcgcctcgtt tccactatca gtggttgccg
     3601 gacgagctgc gtgttgaaaa gggtttagtc cggatacgct caagctgctg gatgcaaaag
     3661 gtcagaaagt ggcgctgaat gaggcgatgg gcagcacgca aagcattatg gttgggtcgg
     3721 atggtgagtt gtacggcgca tccgactcgc gcttggtgga tgatttaacg gcggggtatt
     3781 aattgacatc ccccggcgca atgtgccggg ggataatggt tttatgcggt caataatcgt
     3841 ccgggattat cgatacagag ttttttgagg atcgttttat cgacgccgcg ctccgccaga
     3901 taggccagaa aaacatctgg aacaaatccc cagccattac cgccattttt agcccacatt
     3961 tgtttaagga agacatcgtg gctgagaaca agctgatcgg cgtatcccaa ctcaatgaga
     4021 tgagcgacgg catcggcagt ctcctgcacc cctggcgcta ttccctcttt cgggaaggta
     4081 atgtctaggc caatcatgtc gaattccagc cagacacctt tatcaagcat tttccgctga
     4141 tacgccacgt cttttcctga cggatccgag tgtgcgagag agactttatt tggcgagacg
     4201 cccatttcac ctaacacaat gtcgagtact tcatcaccgc gacgaagcca gcccggcatg
     4261 tgaatattca tcgccacatg aggattgtta atctgtgcca gcgaggcagc ccgcaagctg
     4321 ttatgctcgg cttcggtaaa tgtcggtgaa acacctattt caccgatcat tccggcacga
     4381 atatccgtat cgccaatccc ttgattcaat tctttatcga tcgttgtcgc cagttcatca
     4441 accgttttat gaattctctg gctttcaaat ttttccaggt aggggccgga ggaagcaaca
     4501 atattcagac ctgtttttaa tgcgacttct cgtaatgcct gcgcatctcg tccgatagac
     4561 tcagaccctg tggcatcaat aatggtgcga ccaccgagcg agataaagtt attaatttcg
     4621 aagatcacat cttcaatagg tttgcggtcc atattatcag cgcagcaata aggatcgtgt
     4681 tttaatgccc actggatttc tgccgtgact tttttatcaa caagccgttg tgaaaaagga
     4741 tagcaaggag catccacaac agaggaaaga tcgttgaaca gatgttcatg aggaagtgtt
     4801 agccccatat cttcacgggc gacggggccc gtcacagttt gtagataatc tttcatgatt
     4861 atacctccat tttcttcatt gttttcgagg ttctgtattc cggaatagtg gtaacaattg
     4921 caccgaccag tgcaaacagt gttccgatga tcgtgaccag ataaacgcta ttgcccagcg
     4981 atggaattaa tacgtcaatc aatactgatc ccagtaactg gcccgccgtt gaagcaaccc
     5041 ccagcatcag taaccccaga cctctgacca aaatggccat taaaccgata gacattagtc
     5101 caagcgggcc gccaagatac atccaccaga catctggtaa ttgaacagtg acgtgcccta
     5161 atgcgacacg aatagctagc gctgtgccta aaacacaaaa tccaacgatg aaattctagg
     5221 tgattgaaac cagcatggat cccgtagctt cagatacttt tgcatttcca gcgggctgcc
     5281 atcctgcaag caaaccagct aagaacggaa gaatggcaag taagatgaaa gaggtagaat
     5341 gccactgagg tgacacaaca aaaatcgtag caataaccgc aaataatgca ccgatgatgc
     5401 gataaggggt aaagtatttt ttctcgtcga caccgatacc aaagcgatcg caaagtaaac
     5461 cagacagcaa tagcgcggag atcagtgcgg tttgaaacgt tgcgaccccg agtgcgctgg
     5521 ctgatgcgcc ttcagaaaat accaccatcg ctccacagaa accggcaaac cagttccaga
     5581 gaggaacttt tcggttttta atcagagaag gaattgccgc aaattgttgc cgggtttctt
     5641 ttcgcgccat aataataaaa aacatcacga ctaaaccact ggcaaaggag ataactgcgc
     5701 atgcattacc atcctgtaac cagtgaccta attgaccatt caccgctgat tgcatagggg
     5761 agagcatacc cgcaagaatc gtggcaagca tccataaggg agttgagtac ttattctttt
     5821 tcatacatca atccttctat tatagtaaat ggagtaactg gagttacccc attattatta
     5881 ttatcttgca atatgagtca gtatatttac ccacaacgcg gtatagaacg gccaggacat
     5941 aaactgctgt gtaccccagt gcggtgaaca gtcactcata aagcaggcta ttttcccgtt
     6001 gtgatagtta ccaaagacca gtaatggagc gttgtttatt gttaatacca cctcagcatt
     6061 ttctttagcg atcgcccggt tataacctag gaaaaaagga tattcagaga accctttaat
     6121 aactggatgt tcaggttgtg atggctgtgc aataacaccc tctggttttt cgacacgatc
     6181 gtcaccatct aacatcgtaa ccgggagcac atcagccaga actgtatttt tataattggc
     6241 ttttgcttca attcccatga atgagagata gccgccaatc atcaataacc caccaccgtt
     6301 attcacatat tctttaatca gttcgagagc gtttggtttt atgcgaagct gataaaaagt
     6361 atcattttgt agcaggaaag tattactacc aatatcacta ataacgatgg catcatattg
     6421 ttctaactgt gccacatctt cagggaaggc aatttgtacc gtatgtgctg gcatataggt
     6481 gacatctacc tgactatttt tcagacactg gagtaaccag gtcgcacctt cttcatattt
     6541 acttgaggta aaactgtcat atccttttga atgaatcata tgaatatgcc aggattcccc
     6601 aataaagagc acttttagtg attttttggt gttattcatt ctctgtccct tcttaatgcg
     6661 taaaaatagt ttgctgataa tgtatactct gaattcgatg tatcacagat tcatgttcag
     6721 gcatgtcgga agcattgctt gtctccaccg ctagggatgc aaaggcgctg gcataacaca
     6781 gtgctgattc cagtgatttt cctttcgcaa gtcctgatgc cagagagccg ttaaacgcat
     6841 ccccggctcc tgccgtattt ttaacgaccg ctggaaacgc tggcgaatga atgaattttt
     6901 tgccatcaaa tgcgagcgag cccttgctac cgagcgtgat aaccgtgttt tttacccctt
     6961 tattgtggat agcttctgca gctcgtttag ctgattcaag atcgtgtact gatcttaccc
     7021 agcaatagtg gacacgcggc taagtgagta aactctcagt cagaggtgac tcacatgaca
     7081 aaaacagtat caaccagtaa aaaaccccgt aaacagcatt cgcctgaatt tcgcagtgaa
     7141 gccctgaagc ttgctgaacg catcggtgtt actgccgcag cccgtgaact cagcctgtat
     7201 gaatcaca
//
LOCUS       DAPGUL010000183         7119 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.187, whole genome shotgun sequence.
ACCESSION   DAPGUL010000183 DAPGUL010000000
VERSION     DAPGUL010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7119
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.187"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            99..1433
                     /gene="adeQ"
                     /locus_tag="RHX21_004429"
                     /gene_synonym="yicO"
     CDS             99..1433
                     /gene="adeQ"
                     /locus_tag="RHX21_004429"
                     /gene_synonym="yicO"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418120.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine permease AdeQ"
                     /protein_id="HDV1989516.1"
                     /translation="MNNDNTDYVSNESGTLSRLFKLPQHGTTVRTELIAGMTTFLTMV
                     YIVFVNPQILGAAQMDPKVVFVTTCLIAGIGSIAMGIFANLPVALAPAMGLNAFFAFV
                     VVGAMGISWQTGMGAIFWGAVGLFLLTLFRIRYWMISNIPLSLRIGITSGIGLFIALM
                     GLKNTGVIVANKDTLVMIGDLSSHGVLLGILGFFIITVLSSRHFHAAVLVSIVVTSCC
                     GLFFGDVHFSGVYSIPPDISGVIGEVDLSGALTLELAGIIFSFMLINLFDSSGTLIGV
                     TDKAGLIDSNGKFPNMNKALYVDSVSSVAGAFIGTSSVTAYIESTSGVAVGGRTGLTA
                     VVVGVMFLLVMFFSPLVAMVPPYATAGALIFVGVLMTSSLARVNWDDFTESVPAFITT
                     VMMPFTFSITEGIALGFMSYCIMKVCTGRWRDLNLCVVVVAALFALKIILVD"
     gene            1486..1938
                     /locus_tag="RHX21_004430"
     CDS             1486..1938
                     /locus_tag="RHX21_004430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418119.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1198 domain-containing protein"
                     /protein_id="HDV1989517.1"
                     /translation="MIWIMLATLAVVFVVGFRVLTSGARKAIRRLSDRLNIDVVPVES
                     MVDQMGKSAGDEFLRYLHRPDESHLQNAAQVLLIWQIVIVDGSEQNLLQWHRILQKAR
                     LAAPITDAQVRLALGFLRETEPEMQDINAFQMRYNAFFQPAEGVHWLH"
     gene            2149..3339
                     /gene="nepI"
                     /locus_tag="RHX21_004431"
     CDS             2149..3339
                     /gene="nepI"
                     /locus_tag="RHX21_004431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418118.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine ribonucleoside efflux pump NepI"
                     /protein_id="HDV1989518.1"
                     /translation="MSEFIAENRGADAITRPNWSAVFSVAFCVACLIIVEFLPVSLLT
                     PMAQDLGISEGVAGQSVTVTAFVAMFASLFITQTIQATDRRYVVILFAVLLTLSCLLV
                     SFANSFSLLLIGRACLGLALGGFWAMSASLTMRLVPPRTVPKALSVIFGAVSIALVIA
                     APLGSFLGELIGWRNVFNAAAVMGVLCIFWIIKSLPSLPGEPSHQKQNTFRLLQRPGV
                     MAGMIAIFMSFAGQFAFFTYIRPVYMNLAGFGVDGLTLVLLSFGIASFIGTSLSSFIL
                     KRSVKLALAGAPLILAVSALVLTLWGSDKIVATGVAIIWGLTFALVPVGWSTWITRSL
                     ADQAEKAGSIQVAVIQLANTCGAAIGGYALDNIGLTSPLMLSGTLMLLTALLVTAKVK
                     MKKS"
     gene            complement(3380..3673)
                     /locus_tag="RHX21_004432"
     CDS             complement(3380..3673)
                     /locus_tag="RHX21_004432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989519.1"
                     /translation="MKPTTLLLIFTFFAMPGIVYAESPFSSLQSAKEKTTVLQDLRKI
                     CTPQASLSDEAWEKLMLSDENNKQHIREAIVAMERNNQSNYWEALGKVECPDM"
     gene            3895..4713
                     /gene="nlpA"
                     /locus_tag="RHX21_004433"
     CDS             3895..4713
                     /gene="nlpA"
                     /locus_tag="RHX21_004433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein NlpA"
                     /protein_id="HDV1989520.1"
                     /translation="MKLTTHHLRTGAALLLAGILLAGCDQSSSDAKHIKVGVINGAEQ
                     DVAEVAKKVAKEKYGLDVELVGFSGSLLPNDATNHGELDANVFQHRPFLEQDNQAHGY
                     KLVAVGNTFVFPMAGYSKKIKTVAQIKEGATVAIPNDPTNLGRALLLLQKEKLITLKE
                     GKGLLPTALDITDNPRHLQIMELEGAQLPRVLDDPKVDVAIISTTYIQQTGLSPVHDS
                     VFIEDKNSPYVNILVAREDNKNAENVKEFLQSYQSPEVAKAAETIFNGGAVPGW"
     gene            complement(4717..5640)
                     /locus_tag="RHX21_004434"
     CDS             complement(4717..5640)
                     /locus_tag="RHX21_004434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HDV1989521.1"
                     /translation="MGSTRKGMLNVLIAAVLWGSSGVCAQYIMEQSQMSSQFLTMTRL
                     IFAGLILLTLSFVHGDKIFSIINNHKDAISLLIFSVVGALTVQLTFLLTIEKSNAATA
                     TVLQFLSPTIIVAWFSLVRKSRPGILVFCAILTSLVGTFLLVTHGNPTSLSISPAALF
                     WGIASAFAAAFYTTYPSTLIARYGTLPVVGWSMLIGGLILLPFYARQGTNFVVNGSLI
                     LAFFYLVVIGTSLTFSLYLKGAQLIGGPKASILSCAEPLSSALLSLLLLGITFTLPDW
                     LGTLLILSSVILISMDSRRRARKINRPARHE"
     gene            complement(5751..6935)
                     /locus_tag="RHX21_004435"
     CDS             complement(5751..6935)
                     /locus_tag="RHX21_004435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter"
                     /protein_id="HDV1989522.1"
                     /translation="MQKTATTPSKILDLTAAAFLLVAFLTGIAGALQTPTLSIFLADE
                     LKARPIMVGFFFTGSAIMGILVSQFLARHSDKQGDRKLLILLCCLFGVLACTLFAWNR
                     NYFILLSTGVLLSSFASTANPQMFALAREHADRTGRETVMFSTFLRAQISLAWVIGPP
                     LAYELAMGFSFKVMYLTAAIAFVVCGLIVWLFLPSIQRNIPVVTQPVEILPSTHRKRD
                     TRLLFVVCSMMWAANNLYMINMPLFIIDELHLTDKLAGEMIGIAAGLEIPMMLIAGYY
                     MKRIGKRLLMLIAIVSGMCFYASVLMATTPAVELELQILNAIFLGILCGIGMLYFQDL
                     MPEKIGSATTLYANTSRVGWIIAGSVDGIMVEIWSYHALFWLAIGMLGIAMICLLFIK
                     DI"
BASE COUNT         1791 a         1601 c         1793 g         1934 t
ORIGIN      
        1 cattaatgtg caattgaaat gtgataatta tcactgaacc gttgttgtca tttgttttac
       61 aaaagcaagg gattaaatct cctccaatgg acaaaaaaat gaataatgac aataccgatt
      121 acgtgagtaa tgaatcaggg acgctttcgc gattatttaa actacctcag catgggacca
      181 ccgtccgcac agaattgatt gcggggatga ccactttttt aaccatggtg tacatcgttt
      241 ttgtgaaccc gcaaatcctc ggcgcggcac aaatggaccc gaaagtggtg tttgttacca
      301 cctgtttgat tgccggtatc ggcagtattg cgatggggat atttgctaac ttacccgtgg
      361 cgctggctcc ggcaatgggg ctgaacgcct tctttgcctt cgtggtcgtg ggggcgatgg
      421 gcatctcctg gcagaccggg atgggcgcaa tattctgggg cgcagttgga ctatttttgc
      481 tcacgctgtt tcgtatccgg tactggatga tctccaacat tcccttaagt ttacgtattg
      541 gtatcaccag cggaattgga ttatttatcg ccttaatggg attaaaaaat actggcgtta
      601 ttgtcgccaa taaagacacg ctggtgatga ttggcgattt aagttctcac ggcgtgttgt
      661 taggtatttt agggtttttt attataaccg tgttgtcatc acgtcatttt catgccgcgg
      721 tgctggtttc tattgtggtg acgtcttgct gtggattatt tttcggtgat gttcatttta
      781 gcggcgtcta ttccattccg cctgatatta gcggcgtcat tggtgaagta gatttgagcg
      841 gcgcgttaac acttgaactc gccggtatca ttttctcctt tatgctaatc aacctatttg
      901 attcatcagg aacattaatt ggtgtaactg ataaagcggg cttaatagat agtaacggta
      961 aattccccaa tatgaataag gcgctgtatg ttgatagcgt cagttcggtg gcgggggcgt
     1021 ttatcggcac ctcgtctgtt actgcctata ttgaaagtac ttctggtgtg gcagtcggtg
     1081 gtcgcacggg gctgactgcg gttgtggttg gcgttatgtt cctgttagtt atgttcttct
     1141 caccgctggt ggcgatggtt cctccttacg caaccgccgg agcgttaatc tttgttggcg
     1201 tgctgatgac ttcgagcctg gcgcgcgtta actgggatga ttttaccgaa tcggtgcctg
     1261 cgtttattac cacggtgatg atgcccttta ctttctcgat caccgaaggg attgcactcg
     1321 gctttatgtc gtactgcatc atgaaagtat gcaccgggcg ctggcgcgat ctgaacctgt
     1381 gtgtggtggt ggtcgcagct ctgtttgcac tgaagattat tctggtggat tagtaactgg
     1441 cgagggtttc cagatatcat gagttctgat tacgcaggag aactcatgat ctggataatg
     1501 ctcgccacgc tggcggtagt gtttgtggtt ggttttcggg tgctgacatc cggggccaga
     1561 aaagcgattc gccgtctcag cgatcggctg aacatcgatg tcgtacccgt ggagtcgatg
     1621 gtcgatcaaa tgggaaagtc agctggtgac gaatttttac gttatttgca tcgtccggat
     1681 gagtcgcacc tgcaaaacgc cgcgcaggtg ttgctcatct ggcaaattgt cattgtcgat
     1741 ggtagcgaac agaacctgct gcaatggcat cggattttac aaaaagctcg cctcgccgcg
     1801 ccgattaccg acgctcaggt caggctggcg ctaggttttc tgcgcgaaac cgaacctgaa
     1861 atgcaggata ttaatgcttt tcagatgcgc tataacgcgt tctttcagcc tgccgagggc
     1921 gttcactggt tgcattgaaa ccgtttcgtc ttatcagcct acagaccgcg cctgacctgt
     1981 cgggtggata agacgttcac gccgcatccg gtaatctttg ccctgttccg tttcgatctt
     2041 aactccagct caagcaacac cgtaaaagtt gcaaaaacgt taaatgcgtc acacatttca
     2101 atgttaaagt ggtcggcttt tcccctgaaa catgccacgg gtaacaccat gagtgaattt
     2161 attgccgaaa accgcggcgc ggatgccatc acccgaccga actggtcagc cgttttctcg
     2221 gtggcgtttt gtgtcgcctg tctgattatc gttgagtttt tgcccgtcag tttgttgacg
     2281 ccaatggccc aggatttagg catttcggaa ggggttgccg ggcaatcggt gaccgtgacc
     2341 gcctttgtgg caatgtttgc cagtttgttt attacccaga caattcaggc tactgaccgc
     2401 cgctacgttg ttattttgtt tgccgttttg ctgacgctct cctgcttgct ggtttccttt
     2461 gctaactcat tcagtttgct tttaatcggt cgtgcctgtc tggggctggc gctgggcggg
     2521 ttctgggcga tgtcggcgtc gctgaccatg cgtctggtgc cgccgcgtac ggtgccgaag
     2581 gcactgtcgg tgatcttcgg cgcggtttct attgcgctgg tgattgccgc gccgttgggc
     2641 agttttttag gcgagcttat cggttggcgc aatgtcttta atgcggcggc ggtgatgggc
     2701 gtgctgtgta ttttctggat tatcaaatca ttgccttcac tgccaggcga accctcgcat
     2761 cagaaacaaa atactttccg cttattacaa cgtccgggtg tgatggcagg gatgatcgcc
     2821 atcttcatgt ctttcgccgg gcagtttgct ttcttcacgt atattcgccc ggtgtatatg
     2881 aacctggcgg gattcggcgt ggatggctta acgctggtgc tgttgagttt tggtatcgcc
     2941 agctttattg gtacgtcgct ttcgtcgttc attcttaaac gttcggtaaa actggcctta
     3001 gcaggcgcgc cgttaatact ggctgtgagt gcgttggtgc tgacgttgtg gggaagcgat
     3061 aaaatcgttg ctaccggcgt ggcgattatc tgggggctaa cttttgcatt ggttcccgtc
     3121 ggctggtcaa cgtggatcac ccgctcgctg gccgatcagg cagaaaaagc cgggtctatt
     3181 caggtggcgg ttattcagct tgctaatacc tgtggcgcgg caatcggcgg ttatgcgctg
     3241 gataatattg gtctgacttc gccgttgatg ttgtccggca cattgatgtt gctgactgca
     3301 ttgttggtta ctgcaaaggt gaaaatgaag aaatcctgat atcaggtaaa gaagcgttgg
     3361 tcagtagttg ttgctgttct tacatatccg ggcattctac cttacccaac gcttcccaat
     3421 aattgctctg attattacgt tccatcgcca cgatggcctc gcgtatatgt tgtttattgt
     3481 tttcatctga caacattaac ttttcccacg cttcatctga taatgacgcc tgtggcgtgc
     3541 aaattttacg taaatcttgt aataccgtgg ttttctcttt tgcggactgc agtgagctaa
     3601 aaggcgactc ggcgtatacg atgcctggca tagcgaaaaa agtgaaaata agcagtagtg
     3661 tcgttggttt catggattca accttttaca aatgtgtatc gaatgaagca taagtgtagt
     3721 ttgctttcat cgctctcatc atgctgtacg aaacgcgctt gcgtggtcag taagaagtgc
     3781 cagactttat attccacttt tattcctttt tattcttatc gatagcgttt cgttttttaa
     3841 accgcagcga ccttaccgct atagtcaggt aatcattaat aaaaggataa aaaaatgaaa
     3901 ctgacaacac atcatctacg gacaggggcc gcattattgc tggccggaat tctgctggca
     3961 ggttgcgacc agagtagcag cgatgcaaaa cacattaaag ttggcgttat aaatggcgca
     4021 gaacaagatg tcgcggaagt cgctaaaaag gtggcaaaag agaaatatgg cctcgatgtt
     4081 gaactggtag gatttagcgg ttcgttgcta ccgaacgatg cgacaaatca tggcgaactt
     4141 gatgcgaatg tcttccagca tcgacccttt cttgaacaag ataatcaggc gcatggttat
     4201 aaactggtag cggtgggaaa tacgtttgtc ttccctatgg cgggttattc caaaaaaatc
     4261 aaaaccgtgg cgcaaataaa agaaggcgcg acagtggcga tccccaacga cccgaccaac
     4321 cttggtcgcg cacttttact gttgcaaaaa gagaagctaa ttactctgaa agagggaaaa
     4381 gggttattac ctaccgcgct ggatataacc gataatcctc gtcatttgca gattatggaa
     4441 ctcgaggggg cgcagctccc gcgcgtactg gatgatccca aagttgatgt agcgattatc
     4501 agcaccactt acattcagca gacagggctt tctccggtgc acgacagcgt atttattgaa
     4561 gataagaatt cgccgtatgt gaatattttg gtggcacggg aagataataa gaatgcagaa
     4621 aacgtgaagg aatttctgca atcttatcaa tcacccgaag tcgctaaagc ggcagaaacc
     4681 atttttaacg gtggcgcggt gcctggctgg taattctcac tcatgccgcg ccggacgatt
     4741 tatttttctg gcgcggcgac gggaatccat tgaaatcaaa atcaccgatg acagaatcag
     4801 cagcgttccc agccagtccg gtaatgtgaa cgtgatcccc agcaacagca aagagagtag
     4861 cgcgctactt aatggttctg cacagctcaa aatgctggct tttggaccgc caattaattg
     4921 tgctcctttc aggtacagac taaatgtcag ggacgtacca atgaccacca aataaaaaaa
     4981 cgccagaatc aaactgccgt taacgacaaa gtttgttcct tgtctggcat aaaaaggcaa
     5041 cagaatcaga ccgccaatca gcatactcca gccgacgact ggtaacgtgc catagcgggc
     5101 aattagcgtt gagggatagg tggtatagaa tgcagcagca aatgccgagg caatgcccca
     5161 gaacaacgcg gcaggagaga tcgataatga cgtcggatta ccgtgtgtca ccaataaaaa
     5221 agtcccgacc agcgatgtca aaatagcgca gaaaaccaga atgcccgggc gcgatttacg
     5281 caccagtgag aaccaggcga cgataatcgt cggtgagagg aattgcagca ccgttgccgt
     5341 ggctgcgttc gatttttcga tggttagcaa aaaagtgagc tgtacagtta gcgcgccaac
     5401 cacggaaaaa atcagcaggc taatggcatc tttatgattg ttaataatag aaaagatttt
     5461 atcgccatga acaaatgaca gcgtcagtag aatcaaaccg gcgaatatca aacgcgtcat
     5521 agtcaaaaac tgcgacgaca tctggctttg ctccatgatg tattgcgcgc agacccctga
     5581 acttccccac aacacggcgg caatcagaac gttcagcatc ccctttctgg tggaacccat
     5641 ttttccctct gcatactgtt ttgtcgttta tgtatgcagg catgatagca aaaatggcga
     5701 ggatggctct gtttgcgcca cgccgatttt tcttagccca gactggtgag ctaaatatct
     5761 ttaataaaca gcaggcaaat catcgcaata cccaacatcc ctatcgccag ccagaacaac
     5821 gcatggtagc tccagatttc aaccataatt ccgtcaacag agccggcgat aatccagccg
     5881 acgcgtgaag tatttgcata taacgttgtc gcagagccta ttttttcagg catcaagtcc
     5941 tgaaaataaa gcatgccgat accacagaga ataccaagga agatggcatt aagaatttgc
     6001 aattccagct caaccgccgg agtcgtcgcc atgagtacgc tggcgtaaaa acacattcca
     6061 ctcacgatag caatgagcat taatagtcgc ttgccaatac gtttcatgta atagcctgcg
     6121 attaacatca tcggaatttc cagaccggca gcgataccaa tcatttctcc agccagttta
     6181 tcggttagat gcagttcatc aataataaat agcggcatat ttatcatgta gagattattc
     6241 gccgcccaca tcattgaaca gaccacaaaa agtagccgcg tatcccgctt cctgtgggtg
     6301 gagggtaaaa tttctacggg ttgggtaacg acaggaatat ttctttgtat tgatggcaaa
     6361 aacaaccaga ctatcagtcc gcaaacaaca aatgcgatgg ctgcggtgag atacatcact
     6421 ttaaaactaa atcccattgc cagttcataa gcgagcggtg gcccgataac ccaggcaagc
     6481 gagatctgag cacgtaaaaa tgtactgaac atgaccgtct cacggcctgt tctgtcggcg
     6541 tgttcacggg cgagggcgaa catttgcggg tttgcggtgg aagcaaaact actcagaagt
     6601 acgcccgttg agaggagaat gaagtagttg cgattccacg caaaaagcgt gcaggccagc
     6661 actccaaata agcaacatag cagaatcagt aatttacggt cgccttgttt atcggagtgc
     6721 cttgccagaa attgactgac cagaattccc ataatagcgc taccggtgaa gaaaaaacct
     6781 accattatag gacgggcttt cagttcatct gcgaggaata tacttagggt aggagtctga
     6841 agagcgcccg caatacccgt cagaaaggcg acaagtaaaa atgccgcggc agtgagatca
     6901 agtatttttg atggagtggt agccgttttt tgcattcttc tgaatcaccg ggcgaaaaaa
     6961 tataactgag ttacaaataa gtaccagtcg aatgagtatt gtattaagaa tttttgagta
     7021 tcgctgatac aaccagaaag caatgctagc gcaatattat agggccagca attgagatta
     7081 ttagtaaaag catgttaaga attaattacc gaatttata
//
LOCUS       DAPGUL010000184         7038 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.188, whole genome shotgun sequence.
ACCESSION   DAPGUL010000184 DAPGUL010000000
VERSION     DAPGUL010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7038
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.188"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(411..1316)
                     /locus_tag="RHX21_004436"
                     /pseudo
     CDS             complement(411..1316)
                     /locus_tag="RHX21_004436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309677.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prophage tail fiber N-terminal domain-containing
                     protein"
     gene            complement(1381..1980)
                     /locus_tag="RHX21_004437"
     CDS             complement(1381..1980)
                     /locus_tag="RHX21_004437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ail/Lom family outer membrane beta-barrel
                     protein"
                     /protein_id="HDV1989523.1"
                     /translation="MRKVCAAILSAAICLAVSGAPAWASEQQATLSAGYLHASTNVPG
                     SDDLNGINVKYRYEFTDTLGLITSFSYANAEDEQKTHYSDTRWHEDSVRNRWFSVMAG
                     PSVRVNEWFSAYAMAGVAYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAW
                     GAGVQFNPTESVAIDIAYEGSGSGDWRTDGFIVGVGYKF"
     gene            complement(2048..5527)
                     /locus_tag="RHX21_004438"
     CDS             complement(2048..5527)
                     /locus_tag="RHX21_004438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="HDV1989524.1"
                     /translation="MGKGSSKGHTPREAKDNLKSTQLLSVIDAISEGPVEGPVDGLKS
                     VLLNSTPVLDSEGNTNISGVTVVFRAGEQEQTPPEGFESSGSETVLGTEVKYDTPITR
                     TITSANIDRLRFTFGVQALVETTSKGDRNPSEVRLLVQIQRNGGWVTEKDITIKGKTT
                     SQYLASVVVDNLPPRPFNIRMRRMTPDSTTDQLQNKTLWSSYTEIIDVKQCYPNTALV
                     GVQVDSEQFGSQQVSRNYHLRGRILQVPSNYNPQTRQYSGIWDGTFKPAYSNNMAWCL
                     WDMLTHPRYGMGKRLGAADVDKWALYVIGQNCDQSVPDGFGGTEPRITCNAYLTTQRK
                     AWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDKVWTYNRSNVVMPDDGAPFRYSFSAL
                     KDRHNAVEVNWIDPDNGWETATELVEDTQAIARYGRNVTKMDAFGCTSRGQAHRAGLW
                     LIKTELLETQTVDFSVGAEGLRHVPGDVIEICDDDYAGISTGGRVLAVNSQTRTLTLD
                     REITLPSSGTTLISLVDGSGNPVSVEVQSVTDGVKVKVSRVPDGVAGYGVWGLKLPTL
                     RQRLFRCVSIRENDDGTYAITAVQHVPEKEAIVDNGAHFDGDQSGTVNGVTPPAVQHL
                     TAEVTADSGEYQVLARWDTPKVVKGVSFLLRLTVAADDGSERLVSTARTTETTYRFTQ
                     LALGNYRLTVRAVNAWGQQGDPASVSFRIAAPAAPSRIELTPGYFQITATPHLAVYDP
                     TVQFEFWFSEKRIADIRQVETTARYLGTALYWIAASINIKPGHNYYFYVRSVNTVGKS
                     AFVEAVGQPSDDASGYLDFFKGEIGKTHLAQELWTQIDNGQLAPDLAEIRTSITDVSN
                     EITQTVNKKLEDQSAAIQQIQKVQVDTNNNLNSMWAVKLQQMQDGRLYIAGIGAGIEN
                     TPAGMQSQVLLAADRIAMINPANGNTKPMFVGQGDQIFMNDVFLKYLTAPTITSGGNP
                     PAFSLTPDGRLTAKNADISGSVNANAGTLNNVTINENCRVLGKLSANQIEGDLVKTVG
                     KAFPRDSRAPERWPSGTITVRVYDDQPFDRQIVIPAVAFRGAKHERENNDIYSSCRLI
                     VKKNGAEIYNRTALDNTLVYTGVIDMPAGRGHMTLEFSVSAWLVNDWYPTASISDLLV
                     VVMKKSTAGISIS"
     gene            complement(5588..6235)
                     /locus_tag="RHX21_004439"
     CDS             complement(5588..6235)
                     /locus_tag="RHX21_004439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="HDV1989525.1"
                     /translation="MAATHTLPLASPGMARICLYGDLQRFGRRIDLRVKTGAEAIRAL
                     VTQLPAFRQKLNEGWYQVRIAGRDAGENELSARLNEPLKNGAVIHIVPRLAGAKSGGV
                     FQAVLGAALIAVAWWNPAGWLGAAAVSGMYAAGASMILGGVAQMLAPKARTPRTQTTD
                     NGKQNTYFSSLDNMVAQGNVLPVLYGEMRVGSRVASQEISTADEGDGGQVVVIGR"
     gene            complement(6133..6876)
                     /locus_tag="RHX21_004440"
     CDS             complement(6133..6876)
                     /locus_tag="RHX21_004440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV1989526.1"
                     /translation="MTETESAILAHARRCAPAESCGFVVRTPEGERYFPCVNISGEPE
                     AYFRMSPEDWLSAEMQGEIVALVHSHPGGLPWLSEADRRLQVQSDLPWWLVCRGTIHK
                     FRCVPHLTGRRFEHGVTDCYTLFRDAYHLAGIEMPDFHRGDDWWRHGQNLYLDNMEAT
                     GFYRVPLTEAQPGDVLLCCFGSSVPNHAAIYCGDGELLHHIPEQLSKRERYTDKWQRR
                     THSLWRHRAWHASAFTGICNDLVAVSTFV"
     gene            complement(6882..>7038)
                     /locus_tag="RHX21_004441"
     CDS             complement(6882..>7038)
                     /locus_tag="RHX21_004441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HDV1989527.1"
                     /translation="CGYHGPAVADEYDQPTSDITKDKCSKCLSGCKFRNNVGNFGGFL
                     SINKLSQ"
BASE COUNT         1452 a         2176 c         1780 g         1630 t
ORIGIN      
        1 tcatctttaa ccaggccgta acgcatttgc atgctattga ttagcccggt tggccctaaa
       61 cggcgtatac tcaggtaacg agatacatta tcagcagtaa gcgaagaagg cagaccgcgc
      121 gccgagatct cgataaagtc aatgtttccg taaggggagc cgtagtcacc gccgttagta
      181 accattagcg ttacatggca attgttgctt ccgggatcgg aaagtttcgc gatctttatg
      241 taaaaagact cattaccagt aacaacgggc caatcgtatt gcgtcatcgg gctgacgagt
      301 cccccgacct tgtcgagata ttctttcgcc ttgttctctg acgctttagc gttggtttcg
      361 ctgacctttg ctgctgactc actatttttc gcgttggttt ctgatttttt ggctgctgtc
      421 gcggaatttg ccgatgcagt ttgtgagtct gctgccgcct gtgcgctgtt atccgcattc
      481 atctcagacg tttttgcggc cttcgcggaa tttcctgccg ccgttgccga ggaagctgca
      541 ctgccggcgc tcgaggctgc gctcgtttct gatgattttg ccgccacttt tgaagccgac
      601 gcatcccggg ctgaggtggc agcttctgac gctttcgtgg tcgcggtgga tgcagaagtg
      661 gccgcagatt tttgtgatgc tgcggcattc gtttctgacg ttttcgctgc accggcactg
      721 gtggctgccg cgctttttga agactctgcg gcggcagcac tttttgatgc ttcagtagcc
      781 tttgttgatg ccgttcctgc gctggaagac gctgactgag ccgacgacgc ggcctgtccg
      841 gctgacgtgc tggctgcgcg tgcggagtcc gcagcatcag tcgcatgggt tgccgcctca
      901 cgggctgatg tgcgggcatc actggctgac ttcttcgcgg ctgccgtgtt ctgtgccact
      961 gcggacgcgt tacgcgccac ctcttccacc atcagttcaa agcggcgcag tgcctccgga
     1021 cggacatcat cctccgtcat ggcaccgaga aaatcattca gcgtacccgg ttgtgagtct
     1081 tcatacacgg tgatggtccc ggcatgcgat ggcgggaagc cttccaccaa cagaataacg
     1141 ctgtactgac cgtactcaac gtccatgctg taacgcccgg cttcatccgg gttttctgag
     1201 gccactgtgt tcaccaccac cgtggtgctg ttgcgcctgg cctttagctg aatggtgcag
     1261 ttttgtatcg gcttacctgc gccatctttc agtacacctg aaatccgtac tgccatattc
     1321 cccccacaaa aaaacccgcc tgaaccggcg ggctgtcata acactgtgtt acctggctaa
     1381 tcagaattta taaccgacac ccacgatgaa accgtcagtg cgccagtcac cactgccgga
     1441 accttcataa gcaatatcaa tggccacgga ttcggtcggg ttaaactgca cgccagcccc
     1501 ccacgccaga gacgtgttgc tgtggcgacc gtcatcactt ccggtcagca catcgtgcgt
     1561 tttccccttg ttgtcagtta cgcggagata atccccggag aaagtcgaca cacggctgta
     1621 agccacaccc gccatcgcat acgcgctgaa ccattcattc acgcgcacag acggccccgc
     1681 catcacgctg aaccagcggt tacgcacgga atcctcatgc cagcgggtat cgctgtaatg
     1741 cgttttttgc tcatcttcag cgttggcata actgaatgac gtaatcagcc ccagcgtgtc
     1801 cgtaaactca taacggtatt tcacgttaat cccgttcaga tcatcactac cgggaacgtt
     1861 cgtcgaggca tgaagatacc ctgcgctcag tgtggcctgc tgctcagacg cccatgcagg
     1921 cgcaccggat acggccagac agatggctgc ggacaaaatg gctgcacaaa ctttacgcat
     1981 aattacctct cgcttttctg caataaaaaa ggcgccagaa atggcgcccg catatgggtt
     2041 ataaaattca gctgatactg atacctgctg tggatttctt catcaccaca accagcaaat
     2101 cactgatact ggctgtggga taccagtcat ttaccagcca cgctgatacc gaaaactcca
     2161 gcgtcatgtg accgcgacca gcaggcatat caataacacc tgtataaacc agcgtattat
     2221 ccagcgcggt acggttataa atttcagcac cgtttttctt cactatcagg cggcatgacg
     2281 aataaatatc gttattctcc cgctcatgtt tagcgccacg aaacgccacc gcgggaataa
     2341 caatctgccg gtcaaacggc tgatcgtcat aaaccctgac ggtaatggtc cctgatggcc
     2401 accgctccgg tgcacgggag tcccggggga aagctttgcc cactgtttta acgagatcgc
     2461 cttcaatctg gttcgcagac agttttccca gaacccgaca gttttcattt atcgtgacat
     2521 tgttgagcgt cccggcgttc gcattcacac tgccactgat atccgcattt ttcgccgtca
     2581 gtcgcccgtc cggtgtaagg gaaaatgcag gaggattacc gccgctggta atggtgggag
     2641 ccgtcagata tttcaggaac acgtcgttca tgaatatctg atcaccctga ccaacaaaca
     2701 tcggctttgt gttgccattc gcaggattaa tcatcgcaat cctgtctgcc gccagcagca
     2761 cctgactctg cattcctgct ggcgtattct caataccggc accgataccc gcaatataaa
     2821 ggcgtccgtc ctgcatctgc tgcagtttca cggcccacat gctgttcagg ttattatttg
     2881 tatcaacctg aaccttctgt atctgctgga tcgctgcact ctggtcttcc agtttcttat
     2941 tgacggtctg tgtgatttca ttgctgacat ccgtaatgga tgtcctgatt tcagccaggt
     3001 caggcgcaag ctgaccgtta tcaatctgcg tccacagctc ctgagccaga tgggttttcc
     3061 ctatctcgcc tttgaaaaaa tccagatagc cggatgcgtc atcactcggc tgaccaacag
     3121 cctccacgaa tgccgatttg ccaacggtgt tcacactgcg aacgtaaaaa taataattat
     3181 ggcccggttt gatattgata ctggcggcta tccagtacaa cgccgtacca agatagcgtg
     3241 ctgtggtttc aacctgcctg atatccgcaa tccgcttttc cgagaaccag aactcaaact
     3301 gtaccgtcgg atcataaacc gcaagatgcg gcgtggcggt tatctgaaaa tagcccggcg
     3361 tcagctcaat ccgcgacggc gctgccggtg cggcaatccg gaacgatacc gacgccggat
     3421 cgccctgctg cccccacgca tttactgccc ggactgtcag cctgtagttc cccagagcca
     3481 gttgtgtgaa gcggtaagtg gtttccgtcg tccgggccgt gctgaccagc cgctcactgc
     3541 cgtcatccgc tgccacggtc aggcgaagca ggaagctcac gcccttcacc accttcggcg
     3601 tgtcccagcg ggccagcacc tggtattccc cgctgtctgc ggtgacttct gcggtcagat
     3661 gctgcactgc tggcggcgtg acaccattca ccgtgccgct ctggtcgccg tcaaagtgcg
     3721 ccccgttatc cacgatggcc tctttttccg gtacatgctg cacggcggtg atggcatacg
     3781 tgccgtcatc gttctcacgg atactcacgc agcggaacag gcgctggcgc agcgtcggca
     3841 gcttcagccc ccatacgccg tatccggcaa cgccgtcagg aacacggctc acttttacct
     3901 tcacgccgtc ggtgacggac tggacctcca cgctgaccgg attgccactt ccgtcaacca
     3961 ggcttatcag cgtggtaccg gaggatggca gcgtgatttc acggtcgagc gtcagcgtcc
     4021 gggtctggct gttcaccgcc agcacgcgcc cgccggtgct gataccggca tagtcatcat
     4081 cgcagatttc aatgacatcg cccggtacat ggcgaagccc ttcagcaccc acgctgaagt
     4141 ccacggtctg cgtttccagc agctccgttt taatcagcca cagcccggcg cggtgtgcct
     4201 gcccccggct ggtacagcca aaggcatcca tcttcgtgac gttacgaccg taacgggcaa
     4261 tggcctgcgt gtcctccaca agctctgtcg ccgtctccca gccgttatcc gggtcaatcc
     4321 agttcacttc aacggcatta tggcggtctt tcagggcgct gaagctgtag cggaatggtg
     4381 cgccatcatc cggcatcacc acattactgc ggttataggt ccacacctta tccgacggcc
     4441 ggtcctgcac gaacgtcagc gtctgcccgt tccataccgg catacagcgc atcgccgagc
     4501 agaaatcact gagcacatcc cacgccttac gttgtgtggt caggtaagcg ttacaggtga
     4561 tgcgcggctc cgtaccgcca aagccgtccg gcaccgactg gtcacaattc tggccgatga
     4621 catacagcgc ccatttgtcc acatccgccg caccgagacg tttccccatg ccgtagcgcg
     4681 ggtgggtcag catatcccac agacaccagg ccatgttgtt gctgtatgcc ggtttaaacg
     4741 tcccgtccca gataccgctg tattgccgcg tctgcgggtt atagttcgac ggcacctgca
     4801 gaatacgccc gcgaagatga taattacggc tcacctgctg gctgccgaac tgctccgaat
     4861 ccacctgcac gccgaccagt gccgtgttcg ggtagcactg tttcacatcg atgatttcgg
     4921 tgtatgacga ccagagcgtt ttgttctgca gctggtctgt ggtgctgtcc ggcgtcatcc
     4981 tgcgcatccg gatattaaac gggcgcggcg gcaggttatc caccaccacc gaggccagat
     5041 actgcgaggt ggttttgccc ttaatggtga tgtctttttc cgtcacccag ccaccattac
     5101 gctgtatctg aaccagcagg cgaacttccg acggattccg gtcccccttt gaggtggttt
     5161 ccaccagtgc ctgcacaccg aaggtaaagc gcagacggtc gatgtttgca gacgtaatgg
     5221 tgcgggtgat cggcgtgtca tatttcactt ccgtacccag caccgtctcg gagccggagg
     5281 attcaaaccc ctccggcggt gtctgctcct gctcaccggc acggaacacc accgtgacac
     5341 cggagatgtt ggtattcccc tcactgtcca gcaccggcgt actgttcagc agcacgcttt
     5401 ttaatccatc caccggacct tcaaccggcc cttcgctgat ggcatcgatc acactcagca
     5461 actgcgtgga cttcaggttg tccttcgctt cgcgcggggt atgcccctta ctgcttcctt
     5521 tacccattcc taacgctcca taaacgacaa aaccgcccgg aggcggtttc acataaaaca
     5581 ttttgcatca gcgaccaatc accacaacct gaccaccgtc cccttcatct gccgtgctga
     5641 tctcctgaga agccacccgc gaccccacgc gcatttcacc gtacagaacg ggcagtacat
     5701 tgccctgggc aaccatgtta tccagtgagg agaaataggt gttctgctta ccgttatccg
     5761 ttgtctgtgt acggggagtt ctggctttcg gtgccagcat ctgcgccaca ccgccaagga
     5821 tcatactggc ccccgcagca tacatgcccg atacagccgc agctcccagc cagcctgcag
     5881 ggttccacca cgccactgca atcagcgccg cacccagcac cgcctgaaac acaccgccac
     5941 tttttgctcc cgcaagacgc ggaacgatgt ggatcacggc accatttttc agcggctcat
     6001 taagacgggc tgataattcg ttttcgcctg catcacgccc ggcaatgcgc acctgatacc
     6061 agccctcatt cagtttctga cgaaacgccg ggagctgtgt gaccagtgcc cggatggctt
     6121 cagcccccgt tttcacacga aggtcgatac ggcgaccaaa tcgttgcaaa tccccgtaaa
     6181 ggcagatgcg tgccatgccc ggtgacgcca gagggagtgt gtgcgtcgct gccatttgtc
     6241 ggtgtacctc tctcgtttac tcagttgttc aggaatatgg tgcagcagct cgccgtcgcc
     6301 acagtaaatg gcggcatgat tcggcaccga tgaaccaaaa cagcacagca gcacgtcgcc
     6361 aggctgcgcc tctgtcagtg ggacacggta aaaacccgtt gcctccatat tgtcaagata
     6421 gagattctga ccgtgacgcc accagtcatc cccgcgatga aaatccggca tctcaatccc
     6481 cgccagatga taagcatccc ggaacagcgt gtaacagtcc gtcaccccgt gctcaaagcg
     6541 ccgcccggtg agatgcggca cacagcggaa cttatgaatc gtcccccggc agaccagcca
     6601 ccacggcaaa tcactctgca cctgcagccg ccggtcggcc tcactcagcc agggcagacc
     6661 accggggtgg ctgtggacca gtgccacaat ctcaccctgc atttctgcac tcagccagtc
     6721 ctccggcgac atccggaaat acgcctccgg ctcaccggaa atattcacgc agggaaaata
     6781 tctttccccc tccggtgttc tcaccacgaa gccgcacgac tccgctggag cacatcgccg
     6841 ggcgtgcgcc agaatcgctg attctgtctc tgtcatggga tttactgcga aagtttgtta
     6901 atggaaagga agccgccaaa gttgccgacg ttattgcgga acttacaacc gctcaggcat
     6961 ttgctgcatt tatccttcgt gatgtcggac gttggctggt catattcatc cgcgaccgcc
     7021 ggaccgtgat aaccgcac
//
LOCUS       DAPGUL010000185         7001 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.189, whole genome shotgun sequence.
ACCESSION   DAPGUL010000185 DAPGUL010000000
VERSION     DAPGUL010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7001)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7001)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7001
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.189"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(38..526)
                     /locus_tag="RHX21_004442"
     CDS             complement(38..526)
                     /locus_tag="RHX21_004442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001499210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989528.1"
                     /translation="MKLSLMLEANRINVQALNMGRIVVDVDGVNLTELINKVAENGYS
                     LRVVEESDQQSTCTLPPFATLAGIRCSTAHITEKDNAWLYSLSHQTSDVGESEWIHFT
                     GSGYLLRTDAWSYPVLRLKRLGLSKTFRRLVITLTRRYGVSLIHLDASAECLPGLPTF
                     NW"
     gene            complement(523..897)
                     /locus_tag="RHX21_004443"
     CDS             complement(523..897)
                     /locus_tag="RHX21_004443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin"
                     /protein_id="HDV1989529.1"
                     /translation="MNTLPDTHVREASHCQSPVTIWQTLLSRLLGQHYGLTLNDTPFA
                     DERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPGFSTCPRSQLINSIDILRARRATG
                     LMTRDNYRTVNNITLGKHPEKR"
     gene            complement(987..1355)
                     /locus_tag="RHX21_004444"
     CDS             complement(987..1355)
                     /locus_tag="RHX21_004444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system YeeU family
                     antitoxin"
                     /protein_id="HDV1989530.1"
                     /translation="MSDTLPGTTHPDDNNDHPWWGLPCTVTPCFGARLVQEGNRLHYL
                     ADRAGIRGRFSDADAYHLDQAFPLLMKQLELMLTSGELNPRHQHTVTLYAKRLTCEAD
                     TLGSCGYVYMAVYPTPETKK"
     gene            complement(1435..1656)
                     /locus_tag="RHX21_004445"
     CDS             complement(1435..1656)
                     /locus_tag="RHX21_004445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 domain-containing protein"
                     /protein_id="HDV1989531.1"
                     /translation="MKIIPRGEAMRIHRQHPASRLFPFCTGKYRWHGSTEAYTGREVQ
                     DIPGVLAVFAERRKDSFGPYVRLMSVTLN"
     gene            complement(1743..2219)
                     /locus_tag="RHX21_004446"
     CDS             complement(1743..2219)
                     /locus_tag="RHX21_004446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RadC family protein"
                     /protein_id="HDV1989532.1"
                     /translation="MQQLSFLPGEMTTRERSLIQRALKTLDRHLHEPGVAFTSTRAAR
                     EWLILNMAGLEREEFRVLYLNNQNQLIAGETLFTGTINRTEVHPREVIKRALYHNAAA
                     VVLAHNHPSGEVTPSKADRLITERLVQALALVDIRVPDHLIVGGSQVFSFAEHGLL"
     gene            complement(2235..2720)
                     /locus_tag="RHX21_004447"
     CDS             complement(2235..2720)
                     /locus_tag="RHX21_004447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HDV1989533.1"
                     /translation="MTTFSHSSTTPSVSVTTASGNNQSQLVATIVPDEQRISFWPQHF
                     GLIPQWVTLEPRVFGWMDRLCEDYCGGIWNLYTLNNGGAFMAPEPDEDDDETWVLFNA
                     MNGNRVEMSPEAAGIAACLMTYSHHACRTECYAMTVHYYRLRDYALQHPECSAIMRII
                     D"
     gene            complement(2812..3630)
                     /locus_tag="RHX21_004448"
     CDS             complement(2812..3630)
                     /locus_tag="RHX21_004448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HDV1989534.1"
                     /translation="MQLASRFGHVNQIRRERPLTREELMYHVPSIFGEDRHTSRSERY
                     AYIPTITVLENLQREGFQPFFACQTRVRDQSRREYTKHMLRLRRDGQITGQHVPEIIL
                     LNSHDGSSSYQMLPGYFRAICTNGLVCGQSLGEVRVPHRGNVVDRVIEGAYEVVGVFD
                     RIEEKRDVMQSLVLPPPARQALAQAALTYRYGDEHQPVTTADILTPRRREDYGKDLWS
                     AYQTIQENMLKGGISGRSAKGKRIHTRAIHSIDTDIKLNRALWVMAETLLESMR"
     gene            complement(3720..3953)
                     /locus_tag="RHX21_004449"
     CDS             complement(3720..3953)
                     /locus_tag="RHX21_004449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF905 family protein"
                     /protein_id="HDV1989535.1"
                     /translation="MSDCHPVLLPEGPFSREQAVAVTTAYRNVLIEDDQGTHFRLVIR
                     NAEGQLRWRCWNFEPDAGKQLNSYLASEGILRQ"
     gene            complement(3959..4636)
                     /locus_tag="RHX21_004450"
     CDS             complement(3959..4636)
                     /locus_tag="RHX21_004450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989536.1"
                     /translation="MNTRALFPLLFTVASFSASAGNWAVKNGWCQTMTEDGQALVMLK
                     NGTIGITGLMQGCPNGVQTLLGSRISINGNLIPTSQMCNQQTGFRAVEVEIGQAPEMV
                     KKAVHSIAERDVSVLQAFGVRMEFTRGDMLKVCPKFVTSLAGFSPKQTTTINKDSVLQ
                     AARQAYARKYDEETTETADFGSYEVKGNKVEFEVFNPEDRAYDKVTVTVGADGNATGA
                     SVEFIGK"
     gene            complement(4784..5464)
                     /locus_tag="RHX21_004451"
     CDS             complement(4784..5464)
                     /locus_tag="RHX21_004451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HDV1989537.1"
                     /translation="MSDNRSRHDRLAVRLSLIISRLMAGESLSLKTLSDEFGVTERTL
                     QRDFHQRLVHLDLEYRNGRYSLRRQSSPGAIPEMLSFIQNTGIARILPLRNGRLITCL
                     TDNQEPSPCLIWLPAPDITATFPECFSQLILAIRQCIHISLMTERWYPSLEPCRLIYY
                     SGSWYLIALQKGKLQVFPLADIKSVSLTSERFERRGHIHSLVAEERFISALPHFSFIH
                     KLINTFNL"
     gene            complement(5667..6551)
                     /locus_tag="RHX21_004452"
     CDS             complement(5667..6551)
                     /locus_tag="RHX21_004452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001557377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HDV1989538.1"
                     /translation="MPFSNSSLSAQVKSYLTFLPEEIRQKILEHLHGVIHYEPVIGIM
                     GKSGTGKSSLCNAIFQSRICATHPLNGCTRQAHRLTLQLGERRMTLVDLPGIGETPQH
                     DQEYRALYRQLLPELDLIIWILRSDERAYAADIAMHQFLLNEGADPSRFLFVLSHADR
                     MFPAEEWNATEKCPSRHQELSLATVTARVATLFPSSFPVLPVAAPAGWNLPALVSLMI
                     HALPPQATSAVYSHIRGENRSEQARKHAQQTFGDAIGKSFDDAVARFSFPAWMLQLLR
                     KARDRIIHLLITLWERLF"
     gene            6652..>7001
                     /locus_tag="RHX21_004453"
     CDS             6652..>7001
                     /locus_tag="RHX21_004453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001702852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989539.1"
                     /translation="MAKNKGICRNKKCSNPVSEFDEANALRLCDDHYKLWKRNKENRR
                     VRNICRIISKYDKSLDREIFYGVRDAAKNKTGKRIIEDAKILHQCRASKQVRKSFHKG
                     VLRSREWLNTQELL"
BASE COUNT         1727 a         1680 c         1912 g         1682 t
ORIGIN      
        1 gcggtttccg tggttaatga tttcatgttg ttcctggtta ccagttgaaa gtgggtaaac
       61 ccggcaggca ttcagcgctg gcatccagat gaatgagact gacgccataa cgtcgggtaa
      121 gtgtgataac cagacgacgg aacgtttttg acagccccag gcgtttaagc cgcagaaccg
      181 gatatgacca cgcatcggta cgtaacagat atccgctacc tgtgaaatga atccattctg
      241 attcaccaac gtcactggtc tgatgcgaca gcgagtacag ccaggcgtta tccttttccg
      301 tgatatgtgc ggtactgcag cgtatgccgg caagggttgc aaacggtggt agtgtgcagg
      361 ttgactgttg gtcggattcc tccaccacgc ggagtgaata accgttttca gcgaccttgt
      421 taatcagttc agtgagatta acaccatcga cgtcaacgac aattcgcccc atgttcagtg
      481 cctgcacatt aattctgttg gcttccagca tcagggaaag tttcatcgtt tctccggatg
      541 cttacccagg gtaatgttat ttaccgttct gtaattgtcg cgggtcatca ggccggtcgc
      601 ccggcgagcc cggaggatat caatactgtt tattaactga gagcggggac aagtgctgaa
      661 tcccggctgg tcggtacgca ccagcgcgta tttttccacg agaaaattca ccgcatcaca
      721 cagtgaaatg ccagcttcaa tatgctgctc aatcacacgt tcatcggcga acggtgtgtc
      781 attcagtgta aggccgtaat gctggcccag tagtcgggag agcagagtct gccagatggt
      841 gacgggagac tggcaatgcg atgcctcccg tacgtgtgta tcgggtaatg tgttcatact
      901 gaagattttc ctgatatgca gagatgaaaa atggaaaagt ggcgtggtga aagcaccagg
      961 ccggagcaga aggttattct ggagagttac tttttcgttt cgggcgtcgg ataaacagcc
     1021 atataaacgt agccacaact gccgagggtg tcggcttcgc aggtcagcct ttttgcatac
     1081 agcgtgacgg tatgctgatg gcggggattc agttcaccgc tggtgagcat gagttccagt
     1141 tgtttcatca gcagcggaaa ggcctggtcc agatggtacg catccgcgtc gctgaaccgg
     1201 cctctgatac cggcgcggtc tgcaaggtaa tgcaaccggt taccctcctg caccagacgt
     1261 gccccaaaac agggcgtcac ggtgcagggt agcccccacc aggggtggtc gttgttatcg
     1321 tcgggatgcg ttgtcccggg gagtgtgtct gacacgataa aatcctcaca gaaaattggt
     1381 taagaatggt ccggtggtgg cgataattct gctcttctga atgcccttcc ggactcagtt
     1441 cagggtgacg ctcatcagcc ggacatacgg accaaaactg tccttacgac gttcagcaaa
     1501 cacggccagc acaccgggaa tatcctgcac ttcacgaccg gtatacgctt cagtgctacc
     1561 gtgccagcgg tatttaccgg tacagaacgg aaaaagacgg gatgcaggat gctgacggtg
     1621 aatacgcatg gcttcaccac gggggatgat tttcatgaga atagtcctcc tgaatgtgaa
     1681 agtaagaaac aactgagaaa gagaaactga agtgatatga aggtgattgt gacggtgacg
     1741 ggttaaagca gaccgtgttc cgcaaaggag aaaacctggc tgccaccgac tatcagatgg
     1801 tccggcaccc ggatatccac cagagccagt gcctgtacca gacgttccgt gataaggcgg
     1861 tctgccttgc tgggtgtgac ttcaccggac gggtgattgt gtgccagcac cacggcagcg
     1921 gcattgtggt acagggcgcg tttaatcact tcccggggat ggacttccgt acggttgatg
     1981 gtgccggtga agagggtttc accggcaatc aactgattct ggttgttcag atacagcacc
     2041 cggaactctt cacgctccag tcccgccatg ttcagaatca gccattcccg tgccgcacgg
     2101 gtggaggtga aggccacgcc gggttcatga agatggcggt ccagggtttt cagggctcgc
     2161 tgaatgaggc tgcgctctct ggttgtcatt tctccgggca gaaaggaaag ctgctgcatt
     2221 gtccctgcct ccattcagtc gatgatgcgc ataatggcgc tgcattccgg atgttgcagg
     2281 gcgtaatccc gcagccggta ataatggacc gtcatggcat aacactcagt acgacaggca
     2341 tgatgactgt acgtcatcag acaggcggca atgccggcgg cttccggact catttcaacg
     2401 cggttaccgt tcatggcatt gaacagtacc catgtttcgt catcatcttc atccggttca
     2461 ggtgccataa atgccccgcc gttgttcagg gtatacagat tccagatacc accgcagtag
     2521 tcttcacaca gacggtccat ccagccgaag acacggggct ccagggtcac ccactgtgga
     2581 atgaggccaa agtgctgcgg ccagaagctg atgcgctgct catcagggac tatggtggca
     2641 accagttgag actggttatt ccctgatgca gtagttacgg aaacagaagg tgtggtggag
     2701 ctatgcgaaa aggttgtcat gagatgattc cttataaaaa gtaaatgaat ggaagaatgc
     2761 ctggggattg gtacagacga gagtcagggc tgcactttca gggaaacagc attagcgcat
     2821 gctctccagc agcgtttccg ccatcaccca caatgcgcgg ttgagcttaa tgtcagtgtc
     2881 aatgctgtga atggcacggg tatggatacg ttttccttta gcgctgcgac ctgaaattcc
     2941 gcctttcagc atattctcct gaatggtctg ataagcactc cacaggtcct taccgtaatc
     3001 ctcccggcgt cgtggcgtca gaatgtcggc ggtggtgacg ggctgatgtt catcaccata
     3061 acggtaagtc agcgccgcct gtgccagcgc ctggcgtgct ggtggcggca ggaccagcga
     3121 ctgcatgaca tcacgctttt cctcaatccg gtcaaacacg cccaccactt cgtaagcacc
     3181 ttcaatcacc ctgtccacca cgtttccccg gtggggcacc cggacttctc ccagcgactg
     3241 accgcagacc aggccattgg tgcagatggc acgaaaatat ccgggtaaca tctggtagct
     3301 ggatgaaccg tcatgggagt tgagcagaat aatttcaggc acatgctgac cggttatctg
     3361 tccgtcccgc cgcagacgca gcatatgttt ggtatattcc cggcggctct ggtcgcgcac
     3421 acgggtctgg caggcgaaga acggctgaaa gccttcccgc tgcagatttt ccaggacggt
     3481 gatggtggga atgtacgcat accgttcact gcgggaggtg tgccggtctt ctccaaaaat
     3541 actcgggacg tggtacatca gttcttcgcg tgtcagtggg cgctcccgac ggatctgatt
     3601 tacatgacca aaacgactgg ctaattgcat actttgctcc ttatgaatga attagcggta
     3661 taaacgaaaa ggccgagtct cccggagaag acgcggcctg atggatgaaa tgaagacgtt
     3721 tattgcctga gaattccctc actggcgaga tacgaattta gctgttttcc ggcatcaggt
     3781 tcaaaattcc agcaccgcca gcgtagctgc ccttcggcat tgcggataac cagccggaaa
     3841 tgcgttccct ggtcatcttc aataagcaca ttgcggtaag ctgttgtgac ggcaaccgcc
     3901 tgttcgcgtg agaaagggcc ttcgggcaat aaaacagggt ggcagtccga cataccggct
     3961 attttccgat aaattcaacg ctggcgccgg tggcattacc gtcagcacca accgtgacgg
     4021 tcactttgtc gtacgcacgg tcttcaggat tgaatacttc aaactcaacc ttattgcctt
     4081 ttacttcgta agagccaaaa tcagcggttt ctgttgtttc ctcgtcgtat ttccgggcgt
     4141 atgcctgtcg ggcagcctgc aggacggaat ctttattaat agtggtcgtc tgtttcgggg
     4201 aaaaaccggc aagtgatgtg acaaatttcg gacagacctt cagcatatca ccgcgggtga
     4261 attccattcg tacaccaaat gcctgtaaaa cggacacatc acgctctgct atggagtgaa
     4321 cggctttttt gaccatttcc ggcgcctgtc cgatttccac ctcaacagcc ctgaatcccg
     4381 tctgctgatt acacatttgt gatgtgggga tcaggttacc gttaatactg atacggctgc
     4441 ccaggagcgt ctgtacacca ttcgggcatc cctgcatcag gccggtaata ccaatcgtgc
     4501 catttttcag cattaccagc gcctgaccat cttccgtcat ggtctgacac cagccgtttt
     4561 tgacagccca gttgccggcg gaggcggaga atgatgccac agtgaacagc aggggaaaaa
     4621 gagctctggt attcatgact gacctctgaa atgaacgtac ggtgttattg ataatgatgg
     4681 aaggtatgca gtgactgttc agggaatgac gtagccgtat atttagtttt ctgttcaaca
     4741 tattgtctcc atacctgtcg ggacggcttt ggcaggccgg cgatcacagg ttaaaggtgt
     4801 tgataagttt atggatgaaa gagaaatgtg gcagggcgga gataaaacgc tcttcagcga
     4861 ccagactgtg gatgtggcct ctccgttcaa accgttctga tgtcaggctg actgatttga
     4921 tatctgccag aggaaagacc tgcagttttc ccttctgtaa cgcgatcaga taccagctac
     4981 cgctgtaata aatgagccgg cagggctcca gtgacggata ccatcgctca gtcatcagag
     5041 agatgtggat acactgtctt attgccagga tgagttgcga gaaacactcg gggaacgttg
     5101 cagtgatatc cggcgccggt agccagataa ggcagggaga gggctcctgg ttgtcggtaa
     5161 gacaggttat cagtcgtccg ttccggagcg gaagtatccg tgcgatcccg gtattctgta
     5221 taaaagaaag catttcaggg atcgcacccg ggctgctctg tcgtctgagg ctgtacctgc
     5281 catttctgta ctctaaatcc aggtgaacca gacgctgatg aaaatcgcgc tgtaaagtac
     5341 gttctgtaac gccaaattca tctgacagtg tttttagtga cagagattct ccggccatca
     5401 gtcggctgat aatgagtgat aagcgaaccg ccaggcgatc atgccgggaa cgattatcag
     5461 acatagatgt gcactccgta agaaaacatc ttttatttca tgatgttatt atgcatcatg
     5521 atgttgaaag gatgtgtcgc atccggataa tcaggaataa aatgcagcag aaaaaatatt
     5581 cttttaatta tctgattttt aagcatgatt tcataaaaag aagaatgctc gttaatccag
     5641 cgacacatcc tgtcggcgtg agtgtgtcag aacagacgct cccacagtgt gatcagcagg
     5701 tggataatgc ggtcccgggc tttacgcaga agctgtaaca tccaggccgg aaaactgaac
     5761 cgggcaacgg cgtcgtcaaa acttttcccg atggcatcac caaaagtctg ttgtgcgtgt
     5821 ttccgggcct gttcagagcg gttttccccc ctgatatgtg aataaactgc gctggttgcc
     5881 tgtggtggca gcgcgtggat catcagtgac accagcgctg gaaggttcca gcctgcaggc
     5941 gcggctacag ggagtaccgg aaatgatgaa gggaacaggg tggccacccg ggctgttact
     6001 gtcgccagtg agagttcctg gtgacgggac gggcattttt ctgtggcatt ccattcttca
     6061 gcaggaaaca tgcgatcggc atggctgaga acaaacagaa agcgcgaggg atctgcgccc
     6121 tcattcagta aaaactgatg catggcaata tcggcagcat acgcacgttc atcactccgc
     6181 aggatccaga taatcagatc cagttccggc agtaactgac gataaagcgc tcggtattcc
     6241 tgatcatgct gcggtgtttc accaatgccg ggcagatcga ccagcgtcat tctgcgttca
     6301 ccgagctgca gggtaagacg atgagcctgg cgggtgcagc cgttcagggg atgcgtggcg
     6361 cagatacggg actgaaaaat ggcattacac aggctgctct tgccggtgcc ggatttaccc
     6421 ataatgccaa tcacgggctc gtaatgaata acaccgtgga gatgttcaag gattttctgg
     6481 cgtatttctt caggaagaaa cgtcagatat gatttcactt gcgcggagag ggaagaattg
     6541 ctgaatggca taccggtatc ctgttgattt cactgaaccg gatcacacta atccggttta
     6601 tcattcaggt aatatgggtg tgaaaatttt tccattgacg ggaagaagag tatggctaaa
     6661 aacaaaggta tttgtcggaa taaaaaatgc agtaatcctg tttcagaatt tgatgaggca
     6721 aatgccttaa ggttatgcga tgatcattat aagctatgga agcgaaataa agagaatcgt
     6781 cgggtcagga atatttgtcg tataatcagt aaatatgaca aaagtctgga ccgggagata
     6841 ttttatggag taagagatgc tgcaaaaaat aaaacgggaa agagaattat tgaggacgca
     6901 aaaatattac atcaatgccg tgcctcaaag caagtaagaa aaagttttca caagggtgtg
     6961 cttcggtcac gggaatggct taatacacag gagttactga g
//
LOCUS       DAPGUL010000186         6972 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.190, whole genome shotgun sequence.
ACCESSION   DAPGUL010000186 DAPGUL010000000
VERSION     DAPGUL010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6972
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.190"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(28..2811)
                     /locus_tag="RHX21_004454"
     CDS             complement(28..2811)
                     /locus_tag="RHX21_004454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310126.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDV1989540.1"
                     /translation="MRNLCFLLTLVATLLLPGRLIAAALPQDEKLITGQLGNGLRYMI
                     YPHAHPKDQVNLWLQIHTGSLQEEDNERGVAHFVEHMMFNGTKTWPGNKVIETFESMG
                     LRFGRDVNAYTSYDETVYQVSLPTTQKQNLQQVMAIFSEWSNAATFEKLEVDAERGVI
                     TEEWRAHQDAKWRTSQARRPFLLANTRNLDREPIGLMDTVATVTPAQLRQFYQRWYQP
                     NNMTFIVVGDIDSKEALALIKDNLSKLPANKAAENRVWPTKAENHLRFNIINDKENRV
                     NGIALYYRLPMVQVNDEQSFVEQAEWSMLVQLFNQRLQERIQSGELKTISGGTARSVK
                     IAPDYQSLFFRVNARDDNIQDAANALMAELATIDQHGFSAEELDDVKSTRLTWLKNAV
                     DQQAERDLRMLTSRLASSSLNNTPFLSPEETYQLSKRLWQQITVQSLAEKWQQLRKNQ
                     DAFWEQMVNNELAAKKALSPAAILALEKEYANKKLAAYIFPGRNLSLTVDADPQAEIS
                     SKETLAENLTSLTLSNGARVILAKSAGEEQKLQITAVSNKGDLSFPAQQKSLIALANK
                     AVSGSGVGELSSSSLKRWSAENSVTMSSKVSGMNTLLSVSARTNNPEPGFQLINQRIT
                     HSTINDNIWASLQNAQIQALKTLDQRPAEKFAQQMYETRYADDRTKLLQENQIVQFTA
                     ADALAADRQLFSSPADITFVIVGNVSEDKLVALITRYLGSIKHSDSPLAAGKPLTRAT
                     DNASVTVKEQNEPVAQVSQWKRYDSRTPVNLATRMALDAFNVALAKDLRVNIREQASG
                     AYSVSSRLSVDPQAKDISHLLAFTCQPERHDELLTLANEVMVKRLAKGISEQELNEYQ
                     QNVQRSLDIQQRSVQQLANTIVNSLIQYDDPAAWTEQEQLLKQMTVENVNTAVKQYLS
                     HPVNTYTGVLLPK"
     gene            complement(2868..5240)
                     /locus_tag="RHX21_004455"
     CDS             complement(2868..5240)
                     /locus_tag="RHX21_004455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor plug domain-containing
                     protein"
                     /protein_id="HDV1989541.1"
                     /translation="MKRVLIPGVILCGADVAQAVDDKNMYMHVFEEMTVYAPVPVPVN
                     GNTHYTSESIERLPTGNGNISDLLRTNPAVRMDSTQSTSLNQGDIRPEKISIHGASPY
                     QNAYLIDGISATNNLNPANESDASSATNISGMSQGYYLDVSLLDNVTLYDSFVPVEFG
                     RFNGGVIDAKIKRFNADDSSVKLGYRTTRSDWLTSHIDENNKSAFNQGSSGSTYYSPD
                     FKKNFYTLSFNQELADNFGVTAGLSRRQSDITRADYVSNDGIVAGRAQYKNVIDTALS
                     KFTWFASDRFTHDLTLKYTGSSRDYNTSTFPQSDREMGNKSYGLAWDMDTQLAWAKLR
                     TTVGWDHISDYTRHDHDTWYTELSCTYGDITGRCTRGGLGHISQAVDNYTFKTRLDWQ
                     KFAVGNVSHQPYFGAEYIYSDAWTERHNQSESYVINAAGKKTNHTIYHKGKGSLGIDN
                     YTLYMADRISWRNVSLMPGVRYDYDNYLSNHNISPRFMTEWDIFADQTSMITAGYNRY
                     YGGNILDMGLRDIRNSWTESVSGNKTLTRYQDLKTPYNDELAMGLQQKIGKNVIARAN
                     YVYREAHDQISKSSRTDSATKTTITEYNNDGKTKTHSFNLSFELAEPLHIRQVDINPQ
                     IVFSYIKSKGNLSLNNGYEESNTGDNQVVYDGNLVSYDSVPVADFNNPLKISLNMDFT
                     HQPSGLVWANTLAWQEARKARIILGKTNAQYISEYSDYKQYVDEKLDSSLTWDTRLSW
                     TPQFLKQQNLTISADILNVLDSKTAVDTTNTGVATYASGRTFWLDVSMKF"
     gene            complement(5278..6963)
                     /locus_tag="RHX21_004456"
     CDS             complement(5278..6963)
                     /locus_tag="RHX21_004456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HDV1989542.1"
                     /translation="MITIPITFCMLIAKYLCLLKPFWLRKNNKTSVLLIIIILAMILG
                     VVKIQVWLNDWNNDFFNALSQKETDKLWQLVLWFPALLGIFVLISVNKTWLIKLLTIR
                     WREWLTDYYLNRWFADKNYYFTQIYGEHKNTDNPDQRIAEDILLLISKTLSLSFGFIQ
                     SLSMLITFTVILWQSAGTLSFTVGGTEWNIQGYMVYTVVLIVIGGTLFTHKVGKRIRP
                     LNVEKQRSEATFRTNLVQHNKQAELIALSNAESLQRQELRDNFHTIKENWHRLMNRQR
                     WLDYWQNIYSRSLSVLPYFLLLPQFISGQINLGGLMKSRQAFMLVSNNLSWFIYKYDE
                     LAELAAVIDRLYEFHQLTEQRPTNKPKNCQHAVQVANASIRTPDNKIILENLNFHVSP
                     GKWLLLKGYSGAGKTTLLKTLSHCWPWFKGDISSPAGSWYVSQTPLIKSGLLKEIICK
                     ALPLPVDDKSLSEVLHQVGLGKLAARIHDHDRWGDILSSGEKQRIALARLILRRPKWI
                     FLDETTSHLEEQEAIRLLRLVREKLPTSGVIMVTHQPGVWNLADDICDISAVL"
BASE COUNT         1801 a         1605 c         1573 g         1993 t
ORIGIN      
        1 gccaacgatg tgttgacggg gctgttatta ttttggcaat aatactccgg tataagtatt
       61 taccggatga gaaagatatt gtttaacggc agtgttaaca ttctctaccg tcatttgttt
      121 caacaattgc tcctgctcag tccatgctgc aggatcgtca tattgaataa gactatttac
      181 aatagtgttc gctaattgtt gaacgctacg ctgttggata tcgaggctgc gctgaacgtt
      241 ttgctggtat tcattcagtt cttgctcact gatcccttta gccagacgct taaccatcac
      301 ttcattcgct aacgttaaca gttcatcatg tcgttctggt tgacaagtaa aagccagcaa
      361 atgactgata tctttggcct gaggatcaac cgagaggcga gaagaaacgc tgtatgctcc
      421 agatgcctgt tcacgaatat taacacgtag atcttttgcc agtgcgacgt taaaagcatc
      481 gagcgccata cgcgtcgcca gattaacagg tgtccgggaa tcataacgct tccactgtga
      541 aacctgtgcc acaggttcat tttgttcttt tacagtaacc gatgcgttgt ccgtcgcgcg
      601 agttaatggt ttacctgcgg ctaatggcga atcagagtgt ttgattgatc ctaagtaacg
      661 cgtaattaac gccacgagtt tgtcttctga gacattaccg acaatgacaa acgtgatatc
      721 cgctggagat gaaaacaact ggcgatcggc agccagcgca tctgcggcag taaactgtac
      781 aatctgattt tcttgcagta atttcgtgcg gtcatcagca tagcgcgtct catacatctg
      841 ctgggcgaat ttctccgctg gacgctggtc gagcgttttc aacgcctgaa tttgagcatt
      901 ttgtagcgat gcccaaatat tgtcgttaat cgtgctgtgg gtgattcgct ggttaatcaa
      961 ctgaaaacca ggttcagggt tattagtccg cgcgctaacg gagagcaacg tattcatgcc
     1021 actgacttta ctgctcatgg ttaccgaatt ttccgcactc cagcgtttca agctggaaga
     1081 ggagagctca ccaacgccgc ttccgcttac tgctttattt gccagcgcga taagtgattt
     1141 ttgctgcgca gggaaactta aatcgccttt attcgatacg gcagtaattt gtagcttttg
     1201 ctcttcaccc gcggattttg ccagaataac cctggcacca ttggaaagtg ttaatgatgt
     1261 cagattctca gccagcgttt ctttgctgct aatttccgcc tgtgggtcag cgtctactgt
     1321 taacgataaa tttctgcctg ggaagatgta agccgccagc tttttgttgg cgtactcttt
     1381 ttccagcgcc aggatagccg caggagacaa tgcttttttg gcggcaagct cattgtttac
     1441 catttgctcc caaaatgcgt cctggttctt tcttaactgc tgccattttt ccgccagact
     1501 ttgcacggta atttgctgcc acagacgttt cgaaagttga tatgtctctt ccggcgacaa
     1561 gaacggcgta ttatttaatg agctggatgc caggcgactg gtcagcatac gtaaatcacg
     1621 ttcagcttgc tgatcaaccg catttttcag ccaggtgagg cgggtagatt tgacatcatc
     1681 gagttcttca gcagaaaaac catgctgatc aatggttgcc aactctgcca ttaatgcatt
     1741 cgcagcatcc tgtatattat cgtctcgtgc atttacacgg aaaaacagcg actgataatc
     1801 gggtgcaatt ttaacgctgc gcgcagtgcc gccagaaata gtcttcaact cgcccgactg
     1861 tatgcgttcc tgcagacgtt gattgaacag ctgaactaac atgctccatt cagcttgttc
     1921 gacaaagctt tgctcatcgt tcacttgtac cattggcagg cgataataga gtgcgatgcc
     1981 gttcacccgg ttttctttat cattaatgat attaaagcgc aggtggtttt cggcttttgt
     2041 cggccagacg cgattttcag ctgctttgtt agccggaagc ttacttaaat tatcctttat
     2101 cagcgccagc gcttctttac tgtcgatatc gccgaccacg ataaaggtca tattatttgg
     2161 ttgataccag cgttgataaa attggcgcaa ttgtgccggt gtgaccgtgg cgacagtatc
     2221 catcaggccg ataggttcac ggtctaaatt acgggtatta gccagcagga aaggacggcg
     2281 cgcctgagag gtgcgccatt tcgcatcctg atgggcacgc cattcctcag taattacgcc
     2341 acgttcagcg tctacttcga gtttttcaaa ggttgcggca ttactccatt cactgaagat
     2401 tgccatcact tgttgcagat tttgtttctg cgtagtcggc aaactcacct gatacaccgt
     2461 ttcgtcatag ctggtatagg cattaacatc gcgaccaaaa cgcaggccca ttgactcaaa
     2521 tgtttcgatg actttattac ccggccatgt ttttgtgccg ttaaacatca tatgttctac
     2581 aaaatgagcc acgccgcgct cattgtcttc ttcctgcaat gaaccggtat gaatttgcag
     2641 ccataaattt acctgatcct ttggatgagc atgcggataa atcatatatc gcaagccatt
     2701 gcccagttgc ccggtaatta acttttcatc ctgcggtaag gcggcggcaa tcagccgccc
     2761 ggggagcaac agagttgcca ctaacgtcag taagaaacag aggtttctca taattatctc
     2821 catgcgaaaa ccgggcgaat ttacccggtt aagtaaaatc cgaactatta aaatttcatg
     2881 ctgacatcaa gccagaaagt acggccactg gcgtaggtcg ccacaccggt gttcgttgta
     2941 tcaacagcgg ttttgctatc caatacattg agaatatcgg cactgatcgt caggttttgt
     3001 tgtttcagaa attgtggcgt ccaggacaag cgggtgtccc aggtcaggct gctatccagt
     3061 ttttcgtcaa catactgctt gtaatctgaa tattcgctga tgtattgcgc atttgtctta
     3121 cccaggataa tgcgagcttt acgcgcttct tgccaggcca gcgtattcgc ccacaccaac
     3181 ccgctcggtt gatgcgtgaa atccatgttt aaggagatct ttaatgggtt attaaaatct
     3241 gccactggaa cgctatcgta agaaaccaga ttaccgtcat aaaccacctg gttatcaccg
     3301 gtattgctct cctcataacc attgtttaac gacaagttgc ccttgctctt gatatagcta
     3361 aagacaattt gtgggttaat atctacctgg cggatatgca ggggttcggc cagctcaaaa
     3421 ctgaggttga acgaatgcgt tttggttttg ccatcgttgt tatattcagt aatggtggtt
     3481 ttagtcgcgc tgtcggtacg actgcttttg ctgatttgat catgcgcttc acggtaaaca
     3541 tagtttgcac gcgcaataac gttcttaccg attttctgct gcaatcccat tgccagttca
     3601 tcgttataag gcgttttcaa atcctgataa cgcgtcaggg ttttattgcc tgataccgat
     3661 tccgtccagc tattgcggat atcacgtaat cccatatcaa gaatattccc accatagtaa
     3721 cggttataac ctgcggtaat cattgaggtt tgatcagcaa aaatatccca ttccgtcata
     3781 aagcgcgggg agatattgtg gtttgacaga tagttgtcat agtcataccg cacgccgggc
     3841 attaatgaca cattacgcca gctaatgcga tccgccatat acagtgtgta gttgtcaatt
     3901 cccaggctgc ctttaccttt atggtaaatg gtatggttag ttttctttcc ggcagcatta
     3961 atcacatagg attcagactg gttatggcgt tcagtccatg catcggaata gatgtattcc
     4021 gcgccgaagt agggttgatg cgaaacatta cccacggcga atttttgcca gtccaggcgt
     4081 gttttgaagg tgtaattatc tacagcctgg gaaatgtgtc ctaatccgcc acgggtgcaa
     4141 cgccctgtaa tatcaccata tgtacatgaa agttcggtgt accaggtgtc atgatcgtga
     4201 cgggtataat cactaatatg atcccaacca acggtggtac gaagtttggc ccatgcgagc
     4261 tgcgtatcca tatcccatgc cagaccatag gatttattac ccatttcgcg atcagactgc
     4321 gggaaggtgc tggtattata atcacggctg gagccggtat attttaaggt taaatcgtgg
     4381 gtaaagcggt cgctggcaaa ccaggtaaat ttgctcaatg cagtatcgat aacgttttta
     4441 tactgtgccc gaccggcgac aatgccgtca ttcgaaacat aatccgcgcg ggtgatatca
     4501 gactggcggc gcgataaacc ggcggtaacg ccaaagttat cagcgagttc ctgattaaac
     4561 gacaaggtat aaaagttctt tttaaaatct ggagagtaat aagtacttcc tgaagaacct
     4621 tgattaaatg cgctcttgtt attctcatcg atatgcgatg ttaaccagtc cgaacgcgta
     4681 gtgcgataac ccagtttcac gctgctatca tcagcgttga agcgtttgat ctttgcatca
     4741 attaccccgc cattgaagcg accgaattca accggcacaa aactgtcata aagcgtcaca
     4801 ttgtccagta agctgacatc aagataatac ccctgtgaca tcccgctaat attggttgca
     4861 ctactggcat cggactcatt cgctgggttc aggttattag tggcactaat accatcaatc
     4921 aaataggcat tctggtaggg cgacgcaccg tgaatagaga ttttctccgg gcgaatatct
     4981 ccctggttca acgaggtact ttgcgttgaa tccatgcgta ccgcagggtt ggttctcagc
     5041 agatcgctga tattgccatt cccggtcggt aaacgctcga tgctttcact ggtgtaatgc
     5101 gtgttgccgt ttacgggtac agggacagga gcatagaccg tcatctcttc aaaaacatgc
     5161 atgtacatgt ttttgtcatc gacggcctgc gccacatcag cgccacataa aatgacgcca
     5221 ggaataagaa ctcgcttcat ttatttatat ctccgtacag cagggctttt attgttttta
     5281 taaaaccgcg ctaatgtcac aaatatcatc ggccaggttc cagacaccgg gttgatgtgt
     5341 aaccataatg acgccgcttg tgggtagttt ttcacgcact aaacgcagta agcggatagc
     5401 ctcttgttcc tcaagatgag aggtagtttc gtcaagaaat atccatttcg gacgtcgtaa
     5461 aattaatcgt gccagggcga tacgttgttt ttcgccgctg gaaagaatat ctccccagcg
     5521 atcgtggtca tgaatacgcg cagccaattt ccccagacca acctgatgca gtacttcgct
     5581 caacgattta tcgtctacgg gcaggggaag tgctttacaa ataatctctt tcagtaagcc
     5641 gcttttgatt aacggtgttt gtgacacata ccaactgcca gcaggagaag aaatatcacc
     5701 tttaaaccac ggccagcagt gggataatgt tttaagcagt gtggtttttc ccgcaccaga
     5761 gtagcctttc agtaatagcc atttgcctgg cgaaacatga aagttcaagt tctctaatat
     5821 gatcttatta tcaggcgtac gaatactcgc attagccact tgtaccgcat gttggcaatt
     5881 tttaggctta ttcgtagggc gctgttcagt gagttgatgg aactcataca agcgatcgat
     5941 aaccgcagcc agttcagcaa gttcgtcata tttataaata aaccagctta aattgttcga
     6001 tactagcata aatgcctggc gcgatttcat cagtccgccc agattgatct gcccgctaat
     6061 aaactgcggc aataacagaa agtagggaag aacgctaagc gagcgcgaat aaatattttg
     6121 ccagtaatca agccaccgct gacgattcat taaacgatgc cagttctctt taatggtatg
     6181 aaaattgtcg cgcaactcct ggcgttgtag agactcagca ttgcttagcg caatcagttc
     6241 tgcctgctta ttatgctgca caagattagt tcgaaatgtc gcttcgctac gttgtttttc
     6301 cacattaagc ggacgaatac gtttacccac cttatgggta aataaagttc caccgatcac
     6361 aatgagcacg acggtataga ccatataccc ctggatattc cattctgttc caccaacagt
     6421 gaatgagagc gtacccgcgc tttgccaaag aataacggta aaggtgatca gcatgctaag
     6481 tgactggatg aagccaaatg aaagactgag cgttttgctg atcagtaaga gaatgtcttc
     6541 agcgatacgt tggtcagggt tatctgtatt tttatgctcg ccgtagatct gcgtgaagta
     6601 gtagttttta tctgcaaacc agcgattaag gtagtaatct gttaaccatt cgcgccagcg
     6661 aatagtcagt agtttaatta accatgtttt gtttacggat attaatacaa agatccccag
     6721 cagggcaggg aaccaaagga caagctgcca aagcttatcg gtttctttct ggcttagcgc
     6781 attgaaaaaa tcattattcc agtcgtttaa ccagacctga attttaacca cgccaaggat
     6841 cattgcgagg ataataatga ttaacaacac tgaagtttta ttattcttac gcagccaaaa
     6901 gggcttcagc agacagagat actttgctat caacatacaa aacgtaatgg gaatggttat
     6961 cattagcgaa aa
//
LOCUS       DAPGUL010000187         6914 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.191, whole genome shotgun sequence.
ACCESSION   DAPGUL010000187 DAPGUL010000000
VERSION     DAPGUL010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6914
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.191"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(187..672)
                     /gene="sixA"
                     /locus_tag="RHX21_004457"
     CDS             complement(187..672)
                     /gene="sixA"
                     /locus_tag="RHX21_004457"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohistidine phosphatase SixA"
                     /protein_id="HDV1989543.1"
                     /translation="MQVFIMRHGDAALDAASDSVRPLTTNGCDESRLMANWLKGQKVE
                     IERVLVSPFLRAEQTLEEVGDCLNLPSSAEVLPELTPCGDVGLVSAYLQALTNEGVAS
                     VLVISHLPLVGYLVAELCPGETPPMFTTSAIASVTLDESGKGEFNWQMSPCNLKMAKA
                     I"
     gene            complement(875..3019)
                     /gene="fadJ"
                     /locus_tag="RHX21_004458"
     CDS             complement(875..3019)
                     /gene="fadJ"
                     /locus_tag="RHX21_004458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid oxidation complex subunit alpha FadJ"
                     /protein_id="HDV1989544.1"
                     /translation="MEMASAFTLNVRLDNIAIITIDVPAEKMNTLKAEFASQVRAIIK
                     QLRENKELRGVVFISAKPDNFIAGADINMIGNCKTAQEAEALARQGQKLMAEIHALPI
                     PVIAAIHGACLGGGLELALACHGRVCTDDPKTVLGLPEVQLGLLPGSGGTQRLPRLIG
                     VSTALEMILTGKQLRAKQALKLGLVDDVVPHSILLEAAVELAKQDHPSSRPLPVRERI
                     LAGPLGRALLFKMVGKKTEHKTQGNYPATERILEVVETGLAQGTSSGYDAEARAFGEL
                     AMTPQSQALRSIFFASTEVKKDPGSDAPPAPLNSVGILGGGLMGGGIAYVTACKAGLP
                     VRIKDINPQGINHALKYSWDQLEGKVRRRHLKASERDKQLALISGTTDYRGFAHRDLI
                     IEAVFENLELKQQMVAEVEQNCAAHTIFASNTSSLPIGDIAAHATRPEQVIGLHFFSP
                     VEKMPLVEIIPHAGTSAQTIATTVKLAKKQGKTPIVVRDKAGFYVNRILAPYINEAIR
                     MLTEGERVEHIDAALVKFGFPVGPIQLLDEVGIDTGTKIIPVLEAAYGERFSAPANVV
                     SSILNDDRKGRKNGRGFYLYGQKGRKSKKQVDPAIYPLIGAQGQGRLSAPQVAERCVM
                     LMLNEAVRCVDEQVIRSVRDGDIGAVFGIGFPPFLGGPFRYIDSLGAGEVVAIMQRLA
                     TQYGSRFTPCERLVEMGARGESFWKTTATDLQ"
     gene            complement(3019..4329)
                     /gene="fadI"
                     /locus_tag="RHX21_004459"
     CDS             complement(3019..4329)
                     /gene="fadI"
                     /locus_tag="RHX21_004459"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase FadI"
                     /protein_id="HDV1989545.1"
                     /translation="MGQVLPLVTRQGDRIAIVSGLRTPFARQATAFHGISAVDLGKMV
                     VGELLARSEIPAEVIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVSRACATS
                     FQAVANVAESLMAGTIRAGIAGGADSSSVLPIGVSKKLARVLVDVNKARTMSQRLKLF
                     SRLRLRDLMPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWS
                     DGKLKEEVMTAFIPPYKQLLAEDNNIRGNSSLADYAKLRPAFDRKHGTVTAANSTPLT
                     DGAAAVILMTESRAKELGLVPLGYLRSYAFTAIDVWQDMLLGPAWSTPLALERAGLTM
                     SDLTLIDMHEAFAAQTLANIQLLGSERFAREALGRAHATGEVDDSKFNVLGGSIAYGH
                     PFAATGARMITQTLHELRRRGGGFGLVTACAAGGLGAAMVLEAE"
     gene            complement(4510..4794)
                     /locus_tag="RHX21_004460"
     CDS             complement(4510..4794)
                     /locus_tag="RHX21_004460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcZ/YiiS family protein"
                     /protein_id="HDV1989546.1"
                     /translation="MSKCSADETPVCCCMDVGTIMDNSDCTASYSRVFANRAEAEQTL
                     AALTEKARSVESEPCKISPTFTEESDGVRLDIDFTFACEAEMLIFQLGLR"
     gene            5166..6506
                     /gene="fadL"
                     /locus_tag="RHX21_004461"
     CDS             5166..6506
                     /gene="fadL"
                     /locus_tag="RHX21_004461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311254.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain fatty acid transporter FadL"
                     /protein_id="HDV1989547.1"
                     /translation="MSQKTLFTKSALAVAVALISTQAWSAGFQLNEFSSSGLGRAYSG
                     EGAIADDAGNVSRNPALITMFDRPTFSAGAVYIDPDVDISGRSDLTGQRADADNIAPT
                     AWVPNLHFVAPINDQFGWGASITSNYGLATEFNDNYAAGIYGGKTDLQTINLNLSGAY
                     RLNNSWSFGLGFDAVYAKAKIERTAGSLGPLLSQQLIAQGVPQSWTNGINTPDSQIAH
                     LKGDEWGFGWNAGILYELDKDNRWGLTYRSEVKIDFEGDYKSSINPNLNNILGSMGLP
                     YGTMGATQNGSLTLNLPEMWEISGYNRVAPQWAIHYSLAYTSWSQFQELKAKGDSGQT
                     LFYKDEGFRDAYRIALGTTYYHDKNWTFRTGIAFDDSPVPADKRSISIPDQDRLWLSA
                     GATYAFNEDASIDVGASYMHGQNVKFTEGEGPAAYTFKSEGKAWLFGTNFNYAF"
BASE COUNT         1769 a         1819 c         1610 g         1716 t
ORIGIN      
        1 gctttgtaaa aatacattac aacttagtct catttcgtca gaaattaata gggaagcaga
       61 ggaaaaagtg cgatgaattc tatatcgaag cgtatcaact ccgtgaaggg ttttgagtga
      121 atttctacta ttgcaaaaag acaaatgccc gatgtacagc ttacatcggg cattttttca
      181 aacgaatcag atagctttcg ccatcttcaa attacatggg ctcatctgcc agttgaactc
      241 gccttttccg ctttcatcaa gcgttacgct ggcaatggcc gaggtggtaa acataggcgg
      301 cgtttcgccc ggacataact cggcaaccag atacccgact aacggtaagt gggagataac
      361 caacaccgaa gcaacacctt cattggtcaa cgcctgcaaa taggcactga ccagaccaac
      421 atcgccgcag ggcgttaact ccggcagaac ttctgcactg gaaggcaggt tcagacaatc
      481 ccctacttcc tccagtgttt gctcggctcg caggaacggg ctcaccagaa cgcgttcgat
      541 ttccactttt tgacctttca gccagttcgc catcaggcga gattcgtcac aaccattagt
      601 agtcagagga cgaaccgaat cactggcggc atcgagggct gcgtcgccgt gacgcatgat
      661 aaaaacttgc atattgcacc gcttttgtta accagattcg cccgttttct ttcatctgaa
      721 accagagaaa gaaaacggtg gccggcattg tgccttatcc attcaccgaa tgaaacgctg
      781 ttttttacct caatggcgta agtatagtca atatgcgttt acattttgac cagcaatccg
      841 ccattcagcg cggattcata tagctttgac cttcttattg caggtcagtt gcagttgttt
      901 tccaaaaact ttccccacgc gcacccatct cgactaaacg ctcgcaaggg gtaaaacgtg
      961 aaccatactg cgtggccagt cgttgcatta ttgcaaccac ttcgcccgcg ccgagagaat
     1021 cgatatagcg aaacggtcca ccgagaaatg gcggaaaacc aatgccaaat accgcaccaa
     1081 tatccccgtc acgcacgcta cggataacct gctcatcaac acaacgtact gcttcattca
     1141 gcatcaacat cacacaccgt tcagcaacct gcggtgcgga gagtcgcccc tgcccttgtg
     1201 cgccaatgag cgggtaaatg gcaggatcga cctgtttttt gcttttacgc cctttctgac
     1261 cataaagata gaaacctcga ccattttttc tgcctttgcg atcgtcgttc aaaattgaag
     1321 aaacaacatt tgcaggcgcg ctaaaacgtt ctccataagc ggcttccagt acaggaataa
     1381 ttttagtccc ggtgtcgatt cctacctcat ccaaaagttg gattggacct accggaaaac
     1441 caaatttcac tagcgcggca tcaatgtgct ctacccgttc accttcggtc agcatgcgga
     1501 tagcttcatt aatgtaaggc gctaagatgc gattgacgta aaacccggct ttgtcacgca
     1561 cgacaatggg cgttttgccc tgttttttcg ccagttttac cgtagtggcg atggtttgcg
     1621 ctgatgtacc cgcatgagga ataatctcca ccagcggcat tttttccacc ggactgaaga
     1681 aatgcaggcc gataacttgc tcaggtcgcg tggcgtgagc ggcgatatca ccaatcggta
     1741 aagatgacgt gttcgaagca aagatggtat gagcggcgca attttgctca acttccgcca
     1801 ccatctgttg ttttaattcg agattttcaa acaccgcttc aataatcaga tcgcgatggg
     1861 caaagccgcg atagtccgtc gttccggaga ttaatgccag ctgtttgtca cgttcgctgg
     1921 ctttgagatg acgacggcga actttgccct ccagctgatc ccaactgtac ttcagcgcat
     1981 gatttatgcc ctgcgggttg atatctttaa ttctgaccgg aagccccgct ttacaagcag
     2041 tgacataagc aataccgccg cccatcaagc caccacctaa aattcccacg ctgtttaatg
     2101 gcgcaggcgg cgcatcacta ccgggatctt tcttcacttc cgtactggca aaaaagatac
     2161 tacgcaaagc ttgcgattgt ggcgtcatcg ccagttcgcc aaacgcccgt gcttcagcgt
     2221 catagccact gctggtgccc tgcgctaatc ccgtttcaac aacctccagg atgcgttctg
     2281 tcgccggata attgccttga gttttgtgtt ctgttttctt gccgaccatt ttgaacagca
     2341 gcgcacgacc taacggcccc gccagaatac gctcgcgtac aggtagaggg cgggaagatg
     2401 gatgatcctg ctttgccagc tcaacagcgg cttccagcag aatggagtgc ggaacaacgt
     2461 catccaccag ccccagcttt aatgcctgtt tcgcccgaag ttgttttcca gtgaggatca
     2521 tctctaatgc tgtgctgacg cctatcagac gcggtaaacg ctgggtgccg cctgaaccgg
     2581 gtaacaatcc aagttgtact tcaggcaaac cgagcaccgt tttaggatcg tcagtacaaa
     2641 cgcgaccgtg gcacgccagc gccaactcca gcccaccacc caggcaagcg ccatgaatag
     2701 ccgcgataac cggaatgggc aaagcatgaa tctctgccat taacttttgc ccctgccgcg
     2761 ccagtgcttc cgcttcttgc gctgttttgc agttgccgat catgttgatg tcagctccgg
     2821 cgataaagtt gtctggtttc gcggaaataa agaccacgcc gcgcaactct ttgttttcgc
     2881 ggagttgctt aataatggcg cgcacctgcg aggcaaactc cgccttcagg gtattcattt
     2941 tctcagccgg tacgtcgatg gtgatgatag caatgttgtc cagacgaaca ttaagagtaa
     3001 acgctgatgc catttccatt attccgcctc cagaaccatt gccgcgccaa gcccaccggc
     3061 agcacaggcg gtaactaaac caaatccacc gccgcgacgg cgaagttcat gcaatgtctg
     3121 ggtaatcatc cgcgcgccgg tcgccgcgaa gggatgcccg taagcaatcg aaccgccaag
     3181 cacgttaaat ttgctatcgt ccacttcgcc agtggcatgt gcacgcccca gtgcttcacg
     3241 agcaaaacgt tcactaccca gcaactgaat attcgccagt gtctgagctg caaaggcttc
     3301 gtgcatatcg atcaatgtca gatcgctcat cgtcaaaccg gcacgctcca gcgccagcgg
     3361 tgttgaccag gctggaccga gcaacatgtc ctgccagaca tcaatagcgg taaatgcgta
     3421 gctgcgcaga tatcccagcg gtaccagccc taattctttc gcccgggatt cagtcatcag
     3481 gatcaccgcc gctgcgccat cggtcagcgg cgtactgttc gccgccgtta ccgtgccgtg
     3541 tttacgatca aacgccggac gcagctttgc gtaatcagca agcgaggaat taccgcgaat
     3601 attgttgtct tccgcgagca gttgtttata aggagggata aaggcagtca tcacctcttc
     3661 tttgagtttt ccgtctgacc atgcctgagc ggcacgctga tgcgaacggt gcgctaatgc
     3721 atcttgctgt tctcgggtga tgccgtaggt tttcgccatt tgctctgcag tgtcgcccat
     3781 ccgcaagccg gtagaatatt ctgctaccgc aggtggtacg ggcattaagt cgcgcaaacg
     3841 caggcgagag aagagtttca gacgctggct cattgtgcgg gctttgttga catcaaccag
     3901 cacgcgcgcc agttttttac tgacgccaat tggcaatacc gaagaggaat ctgccccacc
     3961 ggcaatcccc gctcggatag tccccgccat caggctttct gcgacgtttg caaccgcctg
     4021 gaaactggta gcgcaagcgc ggctgacact gtaagcatcg gtatgcacat tcattccagt
     4081 accgagaaca atttcacgcg caatgttggg agcttcaggc atttgtacga cctgaccaaa
     4141 gaccagttgt tcaatcactt cggcggggat ctcgctgcgt gccagcagtt cgcctaccac
     4201 catcttccct aaatcaaccg cggaaatgcc atgaaaagcc gtcgcctggc gggcaaaagg
     4261 cgtacgtaaa ccgctaacaa tggcgatacg atcgccctgg cgggtaacca gcggtaaaac
     4321 ctgacccata acactcccct gtaaaaaaat aaataaagtg gtctgacctg atcatagtct
     4381 taaccatttt tttacattta gccaagcgga gaaaagggaa agtgggagct atgacacaga
     4441 gagaaaagaa gaagagaaaa gaaaacgccc ctgccagcaa ttgacagggg cgtacgtacc
     4501 cgagaggaat taacgcagac ccagctggaa gatcagcatt tcagcttcgc aggcaaaagt
     4561 gaaatcgata tccaggcgca caccatcaga ctcttcagtg aaagtcgggg agattttgca
     4621 cggttcggat tccacgctac gggctttctc agtcagcgcc gccagcgttt gttctgcttc
     4681 tgcgcggttt gcaaacacgc ggctgtaaga cgcggtgcag tcggagttgt ccataatggt
     4741 gccaacatcc atacagcagc aaaccggggt ttcatcagca ctacatttac tcatcgttga
     4801 tttcctctgt atgtgcaccc aaggtgccag ataaacgttg tggatatttt acgcttccgg
     4861 aaagtgctgc tccagttgtt aattctgcaa aatcggataa gtgaccgaaa tcacacttaa
     4921 aaatgatcta aaacaaaatt cacccgaatc catgagtgcg ccacctccaa attttgccag
     4981 ctggatcgcg tttcttagat catatttgaa aaaagataga aacatacttg caacattcca
     5041 gctggtccga cctatactct cgccactggt ctgatttcta agatgtacct cagaccctac
     5101 acttcgcgct cctgttacag cacgtaacat agtttgtata aaaataaatc attgaggtta
     5161 tggtcatgag ccagaaaacc ctgtttacaa agtctgctct cgcagtcgca gtggcactta
     5221 tctccaccca ggcctggtcg gcaggctttc agttaaacga attttcttcc tctggcctgg
     5281 gccgggctta ttcaggggaa ggcgcaattg ccgatgatgc aggtaacgtc agccgtaacc
     5341 ccgcattgat taccatgttt gaccgcccga cattttctgc gggtgcggtt tatattgatc
     5401 cggatgtaga tatttctggg cgttccgatt taacgggcca gcgtgctgat gcagataata
     5461 ttgcaccaac tgcgtgggtg cctaacctac atttcgtagc acctattaac gatcagtttg
     5521 gttggggggc ttctattacc tcgaactatg gtctggccac ggaatttaat gataactacg
     5581 ctgctggaat ctatggcggt aaaaccgatc tgcagacgat caaccttaac cttagcggag
     5641 cctaccgcct taacaatagc tggagttttg gtcttggttt tgatgctgta tacgctaagg
     5701 caaaaattga gcgtactgcc ggttcactcg gtccattgct ttcccaacaa ctgatagcgc
     5761 aaggcgtgcc acaaagttgg acaaacggca tcaatacacc ggattcgcaa attgctcatc
     5821 tcaagggtga tgaatgggga ttcggctgga acgccggtat tctttatgaa ctggataaag
     5881 ataaccgttg gggcctaacc tatcgttcag aagtgaaaat tgactttgaa ggagattaca
     5941 aaagctccat caacccaaat ctgaacaaca ttttgggtag catgggttta ccatatggca
     6001 caatgggtgc aacccaaaat gggtccttaa cgctgaattt acctgagatg tgggaaattt
     6061 ctggctataa ccgtgtcgca ccacaatggg ctatccacta tagtctggcg tataccagtt
     6121 ggagtcaatt ccaggaactg aaagcgaaag gagactctgg tcaaacgctg ttctataaag
     6181 acgaaggttt ccgggatgct taccgtatcg cgttaggtac aacctactac cacgataaaa
     6241 actggacctt ccgtacgggt attgcattcg atgacagccc ggttccggca gataaacgtt
     6301 ctatctctat cccagatcag gatcgtctgt ggttaagtgc aggtgcgact tatgcattta
     6361 atgaagatgc atccattgac gttggtgcat cttatatgca cggtcagaat gtgaagttta
     6421 ctgaaggtga agggccagca gcatatacct ttaaatctga aggtaaagcc tggctgttcg
     6481 gtactaactt taactacgcg ttctgataac gcgttcgcct ggataaagtc acctgctatg
     6541 caggtgactt taactccccc acttcaccga aagtagtttc ctcattgctt gcctcctgag
     6601 ttttgcaaac agcctgatgg cagcttgccc tttcaaatca gtaagtggta tccacagaca
     6661 aacctgaagg gaaacgcata ttttcaggcg ttctgctcgt ccttctcaaa gagtttactt
     6721 ttctgaattt ccaggatact caaccccctg gctattgtgc gctcatacac tcaaattaaa
     6781 gataggctct aaataaatga gcgttttttg atagtctatt tcattaggta atatatattt
     6841 gtaacaaatc aatcaaaatg gaataaaatc atgctaccat ctatttcaat caacaatacc
     6901 agtgcagctt accc
//
LOCUS       DAPGUL010000188         6589 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.192, whole genome shotgun sequence.
ACCESSION   DAPGUL010000188 DAPGUL010000000
VERSION     DAPGUL010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6589)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6589)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6589
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.192"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..676
                     /locus_tag="RHX21_004462"
     CDS             <1..676
                     /locus_tag="RHX21_004462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS66-like element ISEc23 family transposase"
                     /protein_id="HDV1989548.1"
                     /translation="QGKHPEQHLRPFRGILQADAFTGYDRLFSAEREGGALTEVACWA
                     HARRKIHDVYISSKSATAEEALKRISELYAIEDEIRGLPESERLAVRQQRSKVLLTSL
                     HEWMVEKNGTLSKKSRLGEAFSYVLNQWDALCYYSDDGLAEADNNAAERALRAVCLGK
                     KNFMFFGSDHGGERGALLYGLIGTCRLNGIDPEAYLRHILSVLPEWPSNRVDELLPWN
                     VVLTNK"
     gene            complement(735..1526)
                     /locus_tag="RHX21_004463"
     CDS             complement(735..1526)
                     /locus_tag="RHX21_004463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4198 domain-containing protein"
                     /protein_id="HDV1989549.1"
                     /translation="MMKNTGYILALCLTASGHVLAHDVWITGKQAENNITAEIGYGHN
                     FPSKGTIPDRRNFFENPRIYNGKETITLKPASTDYVYKTESASKDNGYVLSTYMKPGY
                     WSRTSSGWKPVSREGRNDVAYCEFVTKYAKSFIPGVQQMPAQLYQSPTGHELEIIPLS
                     DISRFSEDVKLQVLYKTSPLAGAIMELDSVSYLKSSRHTHAVEHKHPVHKAELTFVTN
                     EDGIVTVPSLHIGQWLAKVQNKKSFQDKSLCDETVDVATLSFSRN"
     gene            complement(1533..3503)
                     /locus_tag="RHX21_004464"
     CDS             complement(1533..3503)
                     /locus_tag="RHX21_004464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001555799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HDV1989550.1"
                     /translation="MYMNVIRNVICTLIILPIGLQAETSHSSMAKDTITVVATGNQNT
                     VFETPSMVSVVTNDTPWSQNAVTSAGMLKGVAGLSQTGAGRTNGQTFNLRGYDKSGVL
                     VLVDGIRQLSDMAKSSGTYLDPALVKRIEVVRGPNSSLYGSGGLGGVVDFRTADVADF
                     LPPGETNGLSLWGNIASGDHSTGSGLTWFGKTGKTDALLSVIMRKRGNIYQSDGERAP
                     NKEKPAALFAKGSVGITDSNKAGASLRLYRNNTTEPGNPTQTHGDSGLRDRKTVQNDV
                     QFWYQYAPVDNSLINVKSTLYLSDITIKTNGHNKTAEWRNNRTSGVNVVNRSHTLIFP
                     GAHQLSYGAEYYRQQQKPEGSATLYPEGNIDFTSLYFQDEMTMKSYPVNIIVGSRYDR
                     YKSFNPRAGELKAERLSPRAAISVSPTDWLMMYGSISSAFRAPTMAEMYRDDVHFYRK
                     GKPNYWVPNLNLKPENNITREIGAGIQLDGLLTGNDRLQLKGGYFGTDARNYIATRVD
                     MKRMRSYSYNVSRARIWGWDMQGNYQSDYFDWMLSYNRTESMDASSREWLGSGNPDTL
                     ISDISIPVGHGGVSAGWRAELSAAATHVKKGDPHQAGYAVHSFSLSYKPVSVKGFEAS
                     VTLDNAFNKLAMNGKGVPLSGRTVSLYTRYQW"
     gene            3834..4268
                     /locus_tag="RHX21_004465"
     CDS             3834..4268
                     /locus_tag="RHX21_004465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001362728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HDV1989551.1"
                     /translation="MDKPTDWRSGTRRIFSNEFKLHMVELASKPNANVAQLAREHGVD
                     NNLIFKWLRLWQREGRISRRMPPTIVGPTVSQSFPASPTLVPVELIDTPRCATDAPAP
                     EALSVACAASCHVEFHYGKMMLENPSPELLTVLIRELTGRGR"
     gene            4265..4615
                     /gene="tnpB"
                     /locus_tag="RHX21_004466"
     CDS             4265..4615
                     /gene="tnpB"
                     /locus_tag="RHX21_004466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017901265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HDV1989552.1"
                     /translation="MISLPSGTRIWLVAGVTDMRKSFNGLGEQIQHVLDDNPFSGHLF
                     IFRGRRGDTIKILWADADGLCLFTKRLEEGQFIWPAVRDGKISITRSQLAMLLDKLDW
                     RQPKTSRLNALTML"
     gene            4646..4900
                     /locus_tag="RHX21_004467"
                     /pseudo
     CDS             4646..4900
                     /locus_tag="RHX21_004467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080164.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
     gene            4978..5250
                     /locus_tag="RHX21_004468"
     CDS             4978..5250
                     /locus_tag="RHX21_004468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_145811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989553.1"
                     /translation="MSHNLEHQKVHTRMVKEVLKAVARANNHPYQSVFTDFIAGHPSC
                     TVCFWETFHKMYPDSPYEYVTFCHTCRRFDLYETEAEMKADDPKWW"
     gene            5231..6439
                     /locus_tag="RHX21_004469"
     CDS             5231..6439
                     /locus_tag="RHX21_004469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS91 family transposase"
                     /protein_id="HDV1989554.1"
                     /translation="MTRSGGDFQPRPLKRLFTANQCWTSFLDAGGLRDIEVEAVTKML
                     ACGTRILGVKEYNCDKPECPHVRYVTNSCGSRACPSCGKKATDLWIATQLNRLPDCDW
                     VHLVFTLPDTLWPVFESNRWLLNDVCRLAVENLLYAARKRGLEPGIFCAIHTYGRRLN
                     WHPHVHVSVTCGGLNKHGHWKKLSFLKDAMRSRWMWNMRQLLLKAWSEGLAMPESLSH
                     ITTESQWRSLVLKAGGKYWHVYMSKKTAGGRNTARYLGRYLKKPPIAASRLAHYNGGA
                     SLSFRYLDHKTGETATETLTQRELVARLKQHIPEKFFKMVRYFGFLANRVCGEKLPQV
                     YRALGMDKPEPVAKVCYAQMVKQFLSRDPFECVLCGGRMVYRRAIAGLNVSGLKKNAR
                     DISLLRYMPA"
BASE COUNT         1641 a         1613 c         1704 g         1631 t
ORIGIN      
        1 gcaggggaaa cacccggagc aacacctccg ccccttccgg ggtatcctgc aggcggatgc
       61 gttcacaggt tacgacaggt tgttcagtgc agaacgtgaa ggtggtgcac tgacagaagt
      121 tgcgtgctgg gcccatgccc ggcgaaaaat ccacgatgta tacatcagca gcaaaagtgc
      181 gacggcagaa gaagccctga agcgaatcag tgaactgtac gccatcgagg atgaaatacg
      241 gggattaccg gagtcagagc gtcttgccgt caggcagcag cgaagcaaag tgttactgac
      301 gtcgctgcat gaatggatgg tggagaagaa tggtacgctg tcgaaaaaat ccagactggg
      361 cgaagcgttc agctatgtac tgaatcagtg ggatgccctc tgttattaca gtgatgacgg
      421 tctggcggag gcggataata atgctgcgga aagagcgctt cgtgcagtct gtctcggaaa
      481 gaaaaacttt atgttctttg gcagcgatca cggcggcgag cgtggagcac tgttgtacgg
      541 gctgatcggc acctgccgtc tgaacggtat cgatccggaa gcgtatctgc gccatatcct
      601 gagcgtactg ccggaatggc cttccaaccg agttgacgaa ctcctgccat ggaacgtagt
      661 actcaccaat aaataagcgt caatacggtg ctccgttgac gcttactaca atttcagggc
      721 agggaatagt attgttaatt tcgggagaaa cttaaagttg ccacatcgac agtttcatca
      781 cacaggcttt tgtcctgaaa acttttctta ttttggactt tcgccagcca ctgtccaata
      841 tgaagagaag gtactgtgac gataccatcc tcattagtta caaaggtgag ttctgcttta
      901 tgaacaggat gtttgtgctc aactgcatga gtatgacggg atgatttcag ataactgacc
      961 gagtcaagct ccatgatagc tccggcgagc ggggacgttt tatacaggac ttgcagcttc
     1021 acatcttcac tgaaacgact tatatcggat aacggaatga tttcaagctc atgccccgtt
     1081 ggagactgat agagttgtgc tggcatctgc tgtacaccag gaataaaaga tttcgcatat
     1141 ttagtgacaa actcacagta agccacatca tttctgccct cccggctgac cggtttccat
     1201 cctgaagagg ttctcgacca gtatcccggt ttcatatatg ttgacaaaac gtagccatta
     1261 tctttgcttg cagactcagt tttatagaca taatccgtgg acgctggctt cagtgttatt
     1321 gtctctttcc cgttataaat ccggggattt tcaaagaaat tccttctgtc aggaattgtg
     1381 ccctttgagg ggaaattatg accataacca atctctgcgg taatgttgtt ctctgcctgt
     1441 ttacctgtaa tccagacatc gtgggccagg acatgccccg atgctgtcag acaaagagct
     1501 aagatataac ctgtattttt catcatgatt tgttaccact gataacgggt ataaagactg
     1561 acagttctgc ctgaaagcgg cactcctttg ccattcatgg caagcttgtt gaaggcatta
     1621 tccagagtca ctgatgcctc aaagccttta acacttacag gcttataaga cagtgaaaag
     1681 gaatgtacgg catagccagc ctgatgggga tcgccttttt tcacatgcgt ggctgctgcc
     1741 gaaagttcag cacgccatcc ggcagaaact cctccatgac caacaggtat actgatgtca
     1801 ctgatgagtg tgtcaggatt gccggagccc agccattccc tgctgctggc atccatactt
     1861 tccgtgcggt tataagaaag catccagtca aaataatcag actggtaatt tccctgcata
     1921 tcccatcccc agatacgggc ccgggataca ttataagaat aagaacgcat ccgtttcata
     1981 tccacgcgcg tggcaatata gtttctggca tccgttccga aatatccgcc tttcaactgc
     2041 agccgatcat tgcctgtaag caggccgtcc agttgaatac ctgcgccaat ctcacgggta
     2101 atgttatttt ctggtttcag attaaggtta ggtacccagt aattgggttt acccttgcgg
     2161 taaaaatgta catcatccct gtacatttct gccattgtgg gggcacggaa tgcagaggat
     2221 atggagccgt acatcatcag ccagtctgtc ggtgagactg aaatcgccgc ccttggggac
     2281 aggcgttcgg ctttcagttc tccggcacgg ggattgaagc tcttgtaccg gtcatagcgg
     2341 gaaccgacga taatgttaac cgggtagctt ttcattgtca tttcatcctg gaaatacaac
     2401 gatgtaaagt caatgtttcc ttccggatat agtgtggcag agccttctgg cttctgctgc
     2461 tgacggtaat attcagcgcc ataacttaac tgatgggctc ccggaaaaat cagagtatga
     2521 ctcctgttga caacattaac accggaggtt ctgttgtttc tccattctgc cgttttgttg
     2581 tgaccgtttg tcttgatagt gatatcactg agatataaag ttgactttac attgatgagg
     2641 ctgttatcca caggagcgta ctggtaccag aactgtacgt cattttgtac tgtttttctg
     2701 tcacgcaggc cgctgtcacc atgtgtctga gtgggattgc ccggttcagt ggtgttattc
     2761 cggtagagac gcaagctggc acctgctttg ttactgtctg ttataccgac agagcctttc
     2821 gcaaacaggg ctgcaggttt ttccttgtta ggtgcgcgct caccatcact ttgatagata
     2881 ttacctcttt tacgcataat gacagaaagg agcgcatctg tttttccggt tttaccgaac
     2941 caggtgagcc ccgagcctgt gctgtggtca ccactggcga tatttcccca cagacttaaa
     3001 ccgtttgtct ctccgggggg aaggaaatct gctacatcgg cagttctgaa gtccacaaca
     3061 cctcccagcc cgccactgcc gtacagactg gagtttggtc cgcggacaac ttcgatacgt
     3121 ttgacgagtg ccggatccag ataagtgcca ctgctttttg ccatgtcact gagttgacgg
     3181 atgccgtcaa caagaacaag taccccgctt ttgtcatagc cgcgtagatt aaaggtctgc
     3241 ccattggtcc gtcctgcacc agtctggctg agaccggcaa cacctttcag catgccggct
     3301 gatgtgaccg cattctgact ccatggcgtg tcattcgtga cgacactgac cattgacggc
     3361 gtttcaaata ccgtgttctg atttcctgtc gcgacaacgg tgattgtatc tttagccata
     3421 gaagaatgac tggtctctgc ctgtaaccct atcgggagta tgattaatgt acaaatgacg
     3481 tttctgatta cgttcatata catgcgaaaa tatatgttaa tattgatatg ttataacata
     3541 tcattttatt aatgcaaccc tgatcacgca gcgttcagtg ataaccagtg aatagcgact
     3601 ctaatacccg gtcgctctgc aatgtatcag cgcctgcgac cgatgctatg gatattgatt
     3661 tttctaccga taaagaacca gcaatacgga atttagactg gccccctgaa tctccagaca
     3721 accaatatca cttaaataag tgatagtcgt aagcgtaaag ccaatgccgt ctgtaacacc
     3781 tgctccttgc agactaaatt agagctcctt ctaaattaga cggagttcta ttgatggata
     3841 aacctacaga ctggcgctcc ggaacccgcc ggatattttc taatgaattt aaacttcata
     3901 tggttgaact ggcttcgaaa ccaaatgcca atgttgcaca actggcccgg gaacatggcg
     3961 ttgataacaa cctgattttt aaatggctac gcctctggca aagagaagga cgtatttctc
     4021 gtagaatgcc tccaactatt gtaggcccta cagtatcaca atcttttccg gcctctccga
     4081 ctctggttcc agtggaactt atcgacaccc cgcgctgtgc tacagatgct cctgctccgg
     4141 aggcattatc agttgcttgt gcagcttcct gccatgtgga attccattac ggtaaaatga
     4201 tgctggaaaa tccttcacca gagctgctca cggtgttgat ccgtgagctg accgggaggg
     4261 gacgatgatt tcactcccat caggtacccg tatctggctc gttgccggcg ttactgatat
     4321 gcgtaaatcc ttcaacggtc tgggggagca gatacagcat gtgctggatg ataacccctt
     4381 ctccggtcac ctgtttatct tccgtggccg acggggagac acgattaaaa tcctgtgggc
     4441 tgatgctgat ggtctgtgcc tgttcaccaa acgccttgag gaaggtcagt ttatctggcc
     4501 tgcggtgcgt gacggtaaga tatccattac ccgctcgcaa ctggcaatgc tcctcgataa
     4561 gctggactgg cgtcagccaa aaacatcccg ccttaacgca ctgacaatgt tgtaaaaaac
     4621 tcctgaccgc attataaaaa cggccatgag tcagaaatac ctcattcgca tcgctgagct
     4681 ggaaaggctg ctctctgagc aggctgaagc cctccgtcag aaagaccagc aactgagtct
     4741 ggttgaagag acggaggcct tcctgcgctc tgcactggca cgtgccgaag aaaagatcga
     4801 agaagatgaa cgggaaatag agcatctgcg ggctcagata gaaaaactgc gccggatgct
     4861 gttcggaacc cgttctgaaa aactgcgtcg tgaggttgaa ccacggcagc ctggcggctg
     4921 caaatcgtgg tgtggcagaa tatgagcttt cagagtaacc atccagaatg agttcccatg
     4981 tcacacaacc tggagcacca gaaagtccac accagaatgg tgaaagaggt tctgaaagcc
     5041 gtcgccaggg ccaataatca cccttatcag tctgtattta cagactttat cgccggtcat
     5101 ccctcctgta cggtctgttt ctgggaaacc ttccacaaaa tgtacccgga ttcaccgtac
     5161 gaatacgtca cgttctgcca tacctgccgt cgttttgatt tatacgaaac tgaagcggag
     5221 atgaaggcgg atgacccgaa gtggtggtga ttttcagccc cgaccgctga aacgcctgtt
     5281 cacagccaac cagtgctgga catccttcct ggatgcgggc ggcctgcgcg atatcgaggt
     5341 tgaggctgtc acaaaaatgc tggcctgcgg cacgcggata ctgggtgtga aggaatacaa
     5401 ctgcgataaa cctgagtgcc cccacgtcag atacgtcact aactcatgtg gcagccgtgc
     5461 ctgcccgtcc tgcggaaaaa aggccacaga cctgtggata gcgacacagc tgaatcgtct
     5521 tcctgactgc gactgggtgc acctggtctt caccctgccg gacacgctgt ggccggtgtt
     5581 cgaaagcaac cgctggctgc tgaatgacgt gtgccgtctg gcggtggaga atctgctgta
     5641 tgcagcccgg aaacggggtc tggaacccgg tatcttctgc gccatccata cgtatggccg
     5701 tcgtctcaac tggcatccgc atgtgcatgt gtcagtgacc tgcggaggtc tgaataaaca
     5761 cggacactgg aaaaagctga gcttcctgaa agacgcgatg cgttcgcggt ggatgtggaa
     5821 tatgcggcag ctgcttctga aagcgtggtc agaaggtctg gcgatgccgg aatcgttgtc
     5881 acatatcacg acggaatcac agtggagaag cctggtgctg aaagccggcg gaaaatactg
     5941 gcatgtgtac atgtcgaaga agacagccgg agggcggaat acggcacgct acctgggtcg
     6001 ttatctgaag aagccaccaa tagcggcttc ccggctggcg cattacaacg gaggagcgag
     6061 tctgagcttc cgttacctgg accacaaaac gggagaaacg gcgacggaaa cgctgacaca
     6121 gcgggagctg gtcgcgaggc tgaaacagca catcccggag aagtttttta agatggtgag
     6181 atacttcggg ttccttgcca accgggtgtg tggagagaag ctgccgcagg tgtaccgtgc
     6241 tctggggatg gataagccgg aaccagtggc gaaagtgtgc tatgcacaaa tggtgaaaca
     6301 gttcctgagt cgtgacccgt tcgaatgcgt gctgtgtggc ggccggatgg tataccgccg
     6361 ggccattgcg gggctgaatg tatcagggct gaagaaaaac gcgcgggata tcagtctgct
     6421 gaggtatatg ccggcctgac acaggctaag tgtgcccggg aatcggtgca ggtataaaaa
     6481 acagcctgtt acggtataaa aatcgaccat gcagagagag aaaccaccgg agtggaggga
     6541 aaagcagaaa ggctcacgtg gcataaggcg tggacagcgg tatcgtctg
//
LOCUS       DAPGUL010000189         6552 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.193, whole genome shotgun sequence.
ACCESSION   DAPGUL010000189 DAPGUL010000000
VERSION     DAPGUL010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6552)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6552)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6552
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.193"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(124..276)
                     /locus_tag="RHX21_004470"
     CDS             complement(124..276)
                     /locus_tag="RHX21_004470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="HDV1989555.1"
                     /translation="MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVL
                     AYESKK"
     gene            complement(541..1275)
                     /gene="cysH"
                     /locus_tag="RHX21_004471"
     CDS             complement(541..1275)
                     /gene="cysH"
                     /locus_tag="RHX21_004471"
                     /EC_number="1.8.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708560.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HDV1989556.1"
                     /translation="MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNL
                     PGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLK
                     VYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQ
                     SGSRANLPVLAIQRGVFKVLPIIDWDNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTT
                     RKWEPGMSEEETRFFGLKRECGLHEG"
     gene            complement(1349..3061)
                     /gene="cysI"
                     /locus_tag="RHX21_004472"
     CDS             complement(1349..3061)
                     /gene="cysI"
                     /locus_tag="RHX21_004472"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="assimilatory sulfite reductase (NADPH)
                     hemoprotein subunit"
                     /protein_id="HDV1989557.1"
                     /translation="MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGF
                     KGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKF
                     AGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSN
                     PYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKT
                     TVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGY
                     LPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPI
                     RPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRI
                     TANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERF
                     LPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGN
                     RIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPAR
                     DLWD"
     gene            complement(3061..4860)
                     /gene="cysJ"
                     /locus_tag="RHX21_004473"
     CDS             complement(3061..4860)
                     /gene="cysJ"
                     /locus_tag="RHX21_004473"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent assimilatory sulfite reductase
                     flavoprotein subunit"
                     /protein_id="HDV1989558.1"
                     /translation="MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVL
                     NQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLTAKLNVKLVNAGDYK
                     FKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEF
                     FCQSGKDFDSKLAELGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSV
                     ATGAVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDAL
                     GVWYQNDPALVKELVELLWLTGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYAT
                     LTRSETLLPLVGDKAKLQHYAATTPIVDMVRFSPAQLDAEALINLLRPLTPRLYSIAS
                     SQAEVENEVHVTVGVVRYDVEGRARAGGASSFLADRVEEEGELRVFIEHNDNFRLPAN
                     PETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKE
                     GVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQAL
                     LEVIAEFGGMDTEAADEFLSELRVERRYQRDVY"
     gene            5179..5541
                     /gene="queD"
                     /locus_tag="RHX21_004474"
     CDS             5179..5541
                     /gene="queD"
                     /locus_tag="RHX21_004474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708563.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxytetrahydropterin synthase QueD"
                     /protein_id="HDV1989559.1"
                     /translation="MSTTLFKDFTFEAAHRLPHVPEGHKCGRLHGHSFMVRLEITGEV
                     DPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLL
                     SAVMVKETCTAGCIYRGE"
     gene            5581..6135
                     /locus_tag="RHX21_004475"
     CDS             5581..6135
                     /locus_tag="RHX21_004475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001317283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HDV1989560.1"
                     /translation="MLGCCVLDIWGMTWKTTATLLLLVPVLQAPLARYAWIYRSILES
                     VALMLKNNYDNMRNEMNHFAKHVIITGGGSNSDLFMQIFADMFNLPARRNAINGCASL
                     GAAINKAVGLGLYPDYATAVDKMVRVKDIFIPIESNAKRYDAMNKGIFKDLTKHNDVI
                     LKKSYEVMHGELGNVDSIQSWSNA"
BASE COUNT         1574 a         1716 c         1633 g         1629 t
ORIGIN      
        1 atttgaaatt cataataata aatagagact atatattcac ataaaaaata taaattttaa
       61 aaaagggtgc aggagaccaa accatcacaa ttcagtacgc ggggttttac ccccgcgtgg
      121 tggctacttc ttcgattcgt aagcgagaac tgccttaaac tccataccac gttctctgat
      181 actcaactca cacaacgagt cacctaccat cagcgtgaat cccagtactg tacaacacag
      241 tacgatgatt gccacaaggg catattttgt cagcatgtct tgcctccctg caaagaagag
      301 actaacattc gaattgtttg ggttcgaacg taagcctcag gttgatagaa atatcgcctg
      361 gggcttttgt ccatctggaa cctcgcgaat gcttaacgcc agacagcctc aagcacccga
      421 cgccattcta tacctgataa ttcttccagc ggcgttcacg tttaaaatca ggaatactgc
      481 tcgcaaaata aaaacgcccc catcatttct gacagaggcg tttaatttat ccggcaatat
      541 ttacccttcg tgcaatccac attccctttt taagccaaag aaacgtgttt cttcttccga
      601 catgccaggt tcccatttac gggttgtatg ggtatcaccg accgataaat atccttcatc
      661 ccataatggg tgatatttca ggccatgttt ttgcaggtac tgataaatag ttcggttatc
      721 ccagtcgata atcggcagca ctttaaatac gccacgctga attgccagca ccggtaaatt
      781 ggcgcggctg ccggattgtt cgcggcgcag gccagcaaac cacgtttgcg cattcagttc
      841 tttcagcgcc cggttcatcg gttcgacttt gttgatgtca ttgtactttt caatgccttc
      901 aacgccctgt tcccacagtt tgccgtagcg tgcttcctgc caggcggcgc tttcggtagc
      961 gcggtacact ttcaggttga gcttgagttt gtccgttaac tcgtcaataa agcggtaggt
     1021 ttccgggaac agatagccgg tgtcggtgag gatcaccgga atatccgggt gaatctgatt
     1081 caccagatgc aggctcaccg ccgcctgaat gccaaagctg gaagaaagta catattcacc
     1141 gggcagatta tccagcgccc aggcaacgcg gccttcagcg tccagttttt ccagttcggc
     1201 gttagtttct gccagcgcca gaatgcgatc taccttcggc agttcgttca gggcgtttag
     1261 atcgagtttg gacatagatt cctcactgtt tgccttgcct gatgcgacgc tcacgcgtct
     1321 tatcaggcct acaagaccgg gctgatggtt aatcccacaa atcgcgcgcc ggatcgagca
     1381 ccgggcgaat gatgcccgca cgcaccgtaa agtcgccgaa gccttcaccc gcttcgcgct
     1441 ctttcgccca gcgccctatc agttcatcaa gcgacgccag gatttccggc tcggtgatgt
     1501 tttctttata catccgtggg atacgtgtcc caatgcggtt gccgccaaga tgcagattgt
     1561 agcgacccgg tgctttaccc accaggccca cttccgccag catcgcgcga ccacaaccgt
     1621 tcgggcagcc tgttacacgc atcacgatat gctcatcgct gacaccatgt ttcgccatta
     1681 aattatcgat gttgtcgata aaagacggca ggaaacgctc tgcttccgcc atcgccagcg
     1741 ggcaagtcgg gaatgacacg caggccatcg agttttcacg ctgcggcgtg acggcattca
     1801 ttaacccgct ctctttggcg atcttctcga tcttcgcttt ctcgctttcc ggtacaccgg
     1861 cgatgatcag attctggttc gccgtaatgc ggaaatcgcc tttgtggatc ttcgcgatct
     1921 ccagcaggcc ggttttcagc ggacgccccg gataatcaag gatgcgacca ttttcgataa
     1981 acagcgtcag gtgccagtta tcatcaatgc ccttaaccca gccaatacga tcgcctcgtc
     2041 cggtgaactc atatggacgg atcggttcaa atttgatccc cgcgcgacgc tccacttccg
     2101 ctttaaacgt ctcaaccccc acgcgctcca gcgtgtattt ggttttggca tttttacgat
     2161 cggttcggtt accccagtca cgctgagttg tcacgacggc ttcggccacc gccagcgtat
     2221 gctccagcgg cagatagcca aactcgctcg ccgtgcgggc gtaggttttc ttgttgccgt
     2281 gttcgataga aagcccaccg cccaccagca ggttgaagcc taccagcttg ccgttttcgg
     2341 cgattgccac gaagttcatg tcgttggcat gcagatcgat atcgttctgc ggcgggatca
     2401 ctaccgtggt tttgaactta cgcggcaggt aggtctgacc aaggatcggt tcttcatcag
     2461 tagtggcgac tttttcctgg tcgagccaga tctccgcata cgcgcgggta cgaggcaaca
     2521 gatgctcaga aatcttcttc gcccactcgt acgcttccgc gtgcagctgc gactcgtaag
     2581 ggttcgaggt gcagagtacg ttacggttca tgtcgttagc tgtcgccagc gcatcaagac
     2641 cgaccgagtg cagcatctgg tgcaccggtt tgacgttctt tttcagaatg ccgtggaact
     2701 gaaacgtctg gcggttggtc aggcgaatgc tgccatagat ggtgttttca ccggcaaatt
     2761 tatcgatcgc ttgccactgt ttggtggtga tcacgccacc cggcagacga cagcgcaaca
     2821 gcatcgcatg gcgcggctcc agcttctgtt cagcacgttc ggcgcggatg tcgcggtcat
     2881 cctgctgata catgccgtgg aagcggatca gcaggaagtt atcgccctta aagccgccgg
     2941 tcagaccgtc gtttaaatct tccgcaatgg tgccgcgcag gtagttgctt tcaagcttca
     3001 tgcgctcggc gtctgtcagt ttaccttcga ccactaaagg ccctggatgt ttttcgctca
     3061 ttagtagaca tctcgctgat aacggcgctc tacgcgcagc tcacttaaaa attcatccgc
     3121 cgcttcggtg tccatgccac caaattcggc aatcacttcc agaagtgcct gctcaacgtc
     3181 tttcgccatg cgattagcgt caccgcagac ataaatatgg gcaccgtcat tgatccagcg
     3241 ccacagctcc gcgccctgtt cgcgcagttt gtcttgtacg taaacttttt ctttttggtc
     3301 gcgcgaccag gcgagatcga tccgcgtcag cacaccctct ttgacgtagc gctgccactc
     3361 cacctggtag aggaaatctt ccgtaaagtg cgggttgcca aagaacagcc agtttttacc
     3421 cggtgcttcg tcggcagcac gttgctgcat aaaggcgcgg aacggcgcga tgccggtgcc
     3481 tgggccaatc ataatcaccg gggtttccgg gttagcgggc aggcggaagt tatcgttatg
     3541 ttcgataaat acgcggagtt cgccctcttc ttccacgcgg tccgcgagga agctggaggc
     3601 accaccggca cgggcgcggc cttccacgtc gtaacgcacc acaccaacgg tgacgtgtac
     3661 ttcgttctcg acttccgcct gcgaggaggc gatggaatac agacgcggcg tcagcgggcg
     3721 cagcagatta attagcgctt cggcatcaag ctgtgccggg gagaaacgca ccatgtcaac
     3781 aatcggcgtc gtcgcggcgt aatgctgtaa cttcgcttta tcgcccacca gcggcagcag
     3841 tgtttcactg cgggtaagcg tggcgtaatt ctcaacaatg ttggcggtgt tgacggtcag
     3901 ttcgaagtgc cactgtagcg cttcgttcag aggcaacgtt ttgccctcga cggtgacagg
     3961 ttcatcgcct gtcagccaca gcagttcgac aagttctttc accagtgccg gatcgttctg
     4021 ataccagacg cccagcgcgt cacccggctg gtaacgcagg cccgagtcac ctaagtcaat
     4081 ttcgatatgg cgaacgtctt tttcagagtt acgcccggta attttctggt taacagagag
     4141 gctagccacc agtggcgcgt ctttgctgta cgggctggtg tggatttcat ttaccgcgcc
     4201 agtagcgacg gattgcgaag gtgccgcgac aggcgcacgc gatttaagcg catcaaccac
     4261 gcgggcgcgc cactcgctgg cagcagcctg gtattcaaca tcggcatcga cacggtcgag
     4321 caggcgttca ccgcccagtt ccgccagctt gctgtcgaaa tctttcccgg actggcagaa
     4381 aaattcataa gagctatcgc cgaggctaaa cacggcaaac gcggtgtttt ccagctttgg
     4441 cgcttttttg gagaacagga acttatgcag cgcgacggct tcttccggcg gttccccttc
     4501 cccttgcgtt gacgtcacca cgataagcag tttttcgctg gcgatttgtt tgaatttata
     4561 gtcgcccgcg ttcaccagct taacgttcag ttttgccgtc aataaatcat cgcgtaatgc
     4621 ttcagcaacc cggcgcgcat tgccggtttg cgaagcagag ataatagtta tacccggcat
     4681 ttctgcggct ggcgctggcg tcgctgcaag cgcagcaggc tgctgattga gcacgcccca
     4741 gaaatagcca gaaacccagg caagctgggt gggagttaaa tcggtcgtgg ccgcctgaag
     4801 gcgtgccagt tgctccgggt tcaacggaag caacgcggaa ggtgggacct gtgtcgtcat
     4861 gcgtcgttat gttccagtaa gcaaagctgt ttctgcgccc tgtcagcgcc cataaaacag
     4921 aagagaaggt aaggttaacg gggcaaatgg tgtggattaa agacgggata gcgataacta
     4981 ataaccaaat cgactaacct gttttagcaa tagtctttaa caacaaaata gattaaccaa
     5041 cccaatgaaa aacaaatgaa tttagccaat cattaagata aatcagcgat tttgcgcaac
     5101 aaagtcgttt tagataatgc gaaaaaacag cctttccggt actctacggc ggttttatcg
     5161 tcctgtagag aaattatgat gtccaccacg ttatttaaag atttcacctt cgaagccgct
     5221 caccgcttac cacacgtccc ggaagggcat aaatgtggtc gcctgcacgg gcattccttt
     5281 atggtgcgac tggaaattac cggggaagtc gatccgcata cgggctggat tatcgatttc
     5341 gctgaactaa aagcggcgtt taaaccaacc tacgagcgcc tcgatcacca ttatctcaat
     5401 gatattccag gtctggaaaa cccaaccagc gaggttttag caaaatggat ttgggatcag
     5461 gttaaacccg ttgtgccgct gttaagtgcg gtgatggtaa aagaaacctg taccgcaggt
     5521 tgtatctatc gcggcgaatg ataagagtgt gtcggcggtc aatttccctt aagtaacgct
     5581 atgttagggt gttgtgttct ggatatctgg ggcatgacat ggaagacgac tgcgacatta
     5641 ttattattgg tgccggtatt gcaggcaccg cttgcgcgtt acgcatggat atatcgttcg
     5701 atactggaaa gcgtggctct gatgctgaag aacaattacg acaatatgcg taatgaaatg
     5761 aatcactttg caaagcatgt gatcattact ggcggcggtt cgaacagcga tctgtttatg
     5821 cagatttttg ccgacatgtt caaccttccg gcacgacgta acgccattaa cggttgtgca
     5881 agtctggggg cagcgattaa taaggcggta ggtctgggac tatacccgga ttacgcaacg
     5941 gctgtcgaca aaatggttcg cgtgaaagat atctttatac cgattgagag caatgccaaa
     6001 cgctacgacg cgatgaataa aggcattttc aaagacctaa ccaaacataa tgatgtaata
     6061 ctgaaaaaat cgtatgaagt gatgcatggg gaattgggga atgtggattc gatccagagc
     6121 tggtcgaatg cgtaagtgag gaaggccggg cgggaaactg cccggcctga acatacctga
     6181 atggttatcc ccgctgacgc ggggaacata agttcgacaa cttaaaaaat gataacaagt
     6241 ccggtttatc cccgctgatg cagggaacat aataaaaact ttaactagtt cggtttatcc
     6301 ctgtttttac aaggaatatt aactacactc gatgtcttta gaataaaaga caatacgaat
     6361 cgcactttat caattttcac ttaaagtatg aactggatat ctttattcat aagaactatt
     6421 catcaacagc gtatagaaac ggtaatgtaa aaccactcat tagcctcaaa acaaagacaa
     6481 attttcagat ttattactta atcaatgaat aacaagctta aaaaacaaac tattaaccta
     6541 aagaaaaaat ta
//
LOCUS       DAPGUL010000190         6550 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.194, whole genome shotgun sequence.
ACCESSION   DAPGUL010000190 DAPGUL010000000
VERSION     DAPGUL010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6550
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.194"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(46..1413)
                     /gene="ydfJ"
                     /locus_tag="RHX21_004476"
     CDS             complement(46..1413)
                     /gene="ydfJ"
                     /locus_tag="RHX21_004476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000582800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter YdfJ"
                     /protein_id="HDV1989561.1"
                     /translation="MTIEKHERSTKDLVKAAVSGWLGTALEFMDFQLYSLGAALVFHE
                     IFFPESSTAMALILAMGTYGAGYVARIVGAFIFGKMGDRIGRKKVLFITITMMGICTT
                     LIGVLPTYAQIGVFAPILLVTLRIIQGLGAGAEISGAGTMLAEYAPKGKRGIISSFVA
                     MGTNCGTLSATAIWVFMFFILSKEELLAWGWRIPFLASVVVMVFAIWLRMNLKESPVF
                     EKVNDSNQPTAKPAPAGSMFQSKSFWLATGLRFGQAGNSGLIQTFLAGYLVQTLLFNK
                     AIPTDALMISSILGFMTIPFLGWLSDKIGRRIPYIIMNTSAIVLAWPMLSIIVDKSYA
                     PSTIMVALIVIHNCAVLGLFALENITMAEMFGCKNRFTRMAISKEIGGLIASGFGPIL
                     AGIFCTMTESWYPIAIMIMAYSVIGLISALKMPEVKDRDLSALEDAAEDQPRVVRAAQ
                     PSRSL"
     gene            complement(1471..2490)
                     /locus_tag="RHX21_004477"
     CDS             complement(1471..2490)
                     /locus_tag="RHX21_004477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn-dependent oxidoreductase"
                     /protein_id="HDV1989562.1"
                     /translation="MKSILIEKPNQLAIVEREIPTPSAGEVRVKVKLAGICGSDSHIY
                     RGHNPFAKYPRVIGHEFFGVIDAVGDGVESARVGERVAVDPVVSCGHCYPCSIGKPNV
                     CTTLAVLGVHADGGFSEYAVVPAKNAWKIPEAVADQYAVMIEPFTIAANVTGHGQPTE
                     NDTVLVYGAGPIGLTIVQVLKGVYNVKNVIVADRIDERLEKAKESGADRAINNSQTPL
                     GEIFAEKGIKPTLIIDAACHPSILKEAVTLASPAARIVLMGFSSEPSEVIQQGITGKE
                     LSIFSSRLNANKFPVVIDWLSKGLIKPEKLITHTFDFQHVADAISLFEQDQKHCCKVL
                     LTFSE"
     gene            complement(2502..3716)
                     /gene="rspA"
                     /locus_tag="RHX21_004478"
     CDS             complement(2502..3716)
                     /gene="rspA"
                     /locus_tag="RHX21_004478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="starvation-sensing protein RspA"
                     /protein_id="HDV1989563.1"
                     /translation="MKIVKAEVFVTCPGRNFVTLKITTEDGITGLGDATLNGRELSVA
                     SYLQDHLCPQLIGRDAHRIEDIWQFFYKGAYWRRGPVTMSAISAVDMALWDIKAKAAN
                     MPLYQLLGGASREGVMVYCHTTGHSIDEALDDYARHQELGFKAIRVQCGIPGMKTTYG
                     MSKGKGLAYEPATKGQWPEEQLWSTEKYLDFMPKLFDAVRNKFGFNEHLLHDMHHRLT
                     PIEAARFGKSIEDYRMFWMEDPTPAENQECFRLIRQHTVTPIAVGEVFNSIWDCKQLI
                     EEQLIDYIRTTLTHAGGITGMRRIADFASLYQVRTGSHGPSDLSPVCMAAALHFDLWV
                     PNFGVQEYMGYSEQMLEVFPHNWTFDNGYMHPGDKPGLGIEFDEKLAAKYPYEPAYLP
                     VARLEDGTLWNW"
     gene            complement(3922..4248)
                     /locus_tag="RHX21_004479"
     CDS             complement(3922..4248)
                     /locus_tag="RHX21_004479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnfA family protein"
                     /protein_id="HDV1989564.1"
                     /translation="MIKTTLLFFATALCEIIGCFLPWLWLKRNASIWLLLPAGISLAL
                     FVWLLTLHPAASGRVYAAYGGVYVCTALMWLRVVDGVKLTLYDWTGALIALCGMLIIV
                     AGWGRT"
     gene            4383..4724
                     /locus_tag="RHX21_004480"
     CDS             4383..4724
                     /locus_tag="RHX21_004480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1283 family protein"
                     /protein_id="HDV1989565.1"
                     /translation="MKITLSKRIGLLAFLLPCALALSTTVHAETNKLVIESGDSAQSR
                     QHAAMEKEQWNDTRNLRQKVNKRTEKEWDKADAAFDNRDKCEQSANINAYWEPNTLRC
                     LDRRTGRVITP"
     gene            4759..5319
                     /gene="speG"
                     /locus_tag="RHX21_004481"
     CDS             4759..5319
                     /gene="speG"
                     /locus_tag="RHX21_004481"
                     /EC_number="2.3.1.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine N1-acetyltransferase"
                     /protein_id="HDV1989566.1"
                     /translation="MPSAHSVKLRPLEREDLRYVHQLDNNASVMRYWFEEPYEAFVEL
                     SDLYDKHIHDQSERRFVVECDGEKAGLVELVEINHVHRRAEFQIIISPEYQGKGLATR
                     AAKLAMDYGFTVLNLYKLYLIVDKENEKAIHIYRKLGFTVEGELMHEFFINGQYRNAI
                     RMCIFQHQYLAEHKTPGQTLLKPTAQ"
     gene            complement(5322..6032)
                     /locus_tag="RHX21_004482"
     CDS             complement(5322..6032)
                     /locus_tag="RHX21_004482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416102.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnfC family lipoprotein"
                     /protein_id="HDV1989567.1"
                     /translation="MKYKLLPCLLAIFLTGCDRTEVTLSFTPEMASFSNEFDFDPLRG
                     PVKDFTQTLMDEQGEVTKRVSGTLSEEGCFDSLELLDLENNTVVALVLDANYYRDAET
                     LEKRVRLQGKCQLAELPSAGVSWETDDNGFVIKASSKQMQMEYRYDDQGYPLGKTTKS
                     NDKTLSVSATPSTDPIKKLDYTAVTLLNNQRVGNVKQSCEYDSHANPVDCQLIIVDEG
                     VKPAVERVYTIKNTIDYY"
     gene            6140..6445
                     /locus_tag="RHX21_004483"
     CDS             6140..6445
                     /locus_tag="RHX21_004483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707474.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1161 domain-containing protein"
                     /protein_id="HDV1989568.1"
                     /translation="MKLSTCCAALLLALASPAVLAAPGSCERIQSDISQRIINNGVPE
                     SSFTLSIVPNDQVDQPDSQVVGHCANDTHKILYTRTTSGNVSAPAQSTQDGAPAEPQ"
BASE COUNT         1819 a         1651 c         1416 g         1664 t
ORIGIN      
        1 atatgaataa aaatcccctc tccggtaaga gaagggattg agggtttaca gacttctgga
       61 aggttgcgca gctcttacaa cacgcggttg atcttccgca gcgtcttcca gcgcacttaa
      121 atcacggtct ttcacctctg gcattttcag cgcagagatt aaaccaatta ctgaatatgc
      181 catgatcata atggcgatcg gataccagga ttccgtcatg gtgcagaaaa tacccgccag
      241 gataggacca aaaccggaag cgataagacc accaatttct ttagaaatag ccatccgggt
      301 aaagcggttt ttacagccga acatttctgc catggtaatg ttttccagag caaataatcc
      361 cagcaccgca cagttatgaa tcacaatcag tgcaaccata atggtgctcg gggcatagct
      421 tttatctaca atgatagaaa gcattggcca tgccagcaca atcgcggagg tattcataat
      481 aatatacggg atccggcgac caattttatc ggataaccaa ccaaggaacg gaatggtcat
      541 aaagccgaga atcgaactaa tcatcaatgc atctgttgga attgctttgt taaacaataa
      601 cgtctgcact aaatagcctg caaggaaagt ctgaattaac ccggagttac ccgcctgacc
      661 aaaacgcagc cctgttgcca gccagaagga tttgctctgg aacatgctac cagcaggtgc
      721 aggttttgct gtgggttggt tgctgtcatt aaccttctca aagaccgggc tttcttttag
      781 attcatacgt aaccagatag caaagaccat cacgacaacg ctcgccagga acggtatacg
      841 ccatccccac gccagcagtt cctctttact gagaatgaag aacataaaga cccagattgc
      901 cgttgcgctc aaggttccgc agttagttcc catagctaca aatgaggaga taattccgcg
      961 cttacctttt ggtgcatatt ccgccagcat cgtaccggca ccggaaattt ccgcacctgc
     1021 acccaacccc tgaataatac gcagcgtcac cagcaagatg ggggcaaaaa caccaatctg
     1081 tgcataggtc ggtaacacac caattaaggt ggtacagatc cccatcatgg tgatggtaat
     1141 aaagagcact tttttacgcc ctattctgtc gcccattttg ccgaaaataa atgctccgac
     1201 aatacgcgcc acataacctg caccgtaggt tcccattgcc aaaattaacg ccattgccgt
     1261 tgatgattca ggaaaaaata tttcatgaaa cactaacgct gcgccgagcg aatataactg
     1321 gaaatccata aattcaagcg cagtgcccag ccatcccgat actgctgctt tcaccaaatc
     1381 cttagtgctt ctttcatgtt tttctattgt cataatggtt atctctaaaa aagaggtaag
     1441 atgcgtacta cttactcgcc gttattggta ttattcagaa aaagtgagta agactttgca
     1501 gcaatgtttt tgatcctgtt caaataaact aatggcatca gcaacatgct ggaaatcaaa
     1561 cgtatgggta attaattttt ctggtttaat taacccttta cttaaccagt cgataacaac
     1621 cggaaattta tttgcattta agcgtgaaga gaaaatagag agttcttttc cggtaattcc
     1681 ttgctgaatc acttcagacg gttcactgga gaagcccatc aatacaatac gtgccgctgg
     1741 agaagccagc gttacggcct ctttcaggat agaaggatga caagccgcat cgataattaa
     1801 tgtcggcttg atgccttttt cagcgaaaat ctcgccaagc ggtgtctggc tgttattaat
     1861 cgccctgtct gccccgctct ctttcgcttt ttccagtcgt tcatcaatgc gatcggcaac
     1921 aatcacattt ttaacgttat agacgccttt taatacctga acgatcgtca ggccgattgg
     1981 accggcacca taaaccagaa cggtatcatt ttcagtcggt tgaccatgtc cggttacgtt
     2041 agccgcaatg gtaaaaggtt cgatcatcac cgcatattga tcggccactg cttcaggaat
     2101 tttccacgca ttttttgccg gaaccacggc atattcactg aaaccaccgt cagcgtgcac
     2161 acctaataca gcaagtgtcg tacaaacgtt cggtttacct atagagcacg gatagcaatg
     2221 cccacagctg accaccggat cgacagcaac acgttcaccg actctggcgc tttccacgcc
     2281 gtcacccacc gcatcaatga cgccaaagaa ttcatgtcca atgacgcgcg gatatttcgc
     2341 aaaaggatta tgcccacgat aaatatggct atcagaacca caaattccgg caagtttcac
     2401 ttttactcgt acttcacccg ctgacggggt gggtatttca cgttcgacaa tcgccagttg
     2461 attcggtttt tcaattaata tgcttttcat tatcttactc cttaccagtt ccacagcgtg
     2521 ccatcttcca gacgtgcgac tggtagataa gcaggttcat agggatattt cgccgccagc
     2581 ttttcatcga attcgatgcc aagacccggt ttgtctcccg gatgcatata gccgttatcg
     2641 aaagtccagt tgtgcgggaa gacttcgagc atttgttcgg aataacccat gtattcctgg
     2701 acaccgaaat tggggaccca cagatcaaag tgcagcgctg cagccatgca gactggtgac
     2761 aaatcggaag gaccgtgtga gccagtacgt acctgataca gcgaagcaaa atcggcaatc
     2821 cggcgcatac cggtaattcc gcctgcatgg gtcagcgtgg tgcggatata atcgatgagt
     2881 tgctcttcaa tcagttgttt gcagtcccag atgctgttga agacttcacc cactgcgatg
     2941 ggtgtgacgg tatgttggcg aatgagacgg aagcattcct ggttttctgc aggcgtcggg
     3001 tcttccatcc agaacatgcg ataatcttca atgcttttac caaagcgcgc cgcttcaata
     3061 ggcgttaagc gatggtgcat gtcatgcagc aaatgttcat taaaaccaaa cttgttacgt
     3121 accgcgtcaa acaatttcgg catgaaatcg aggtatttct ccgtcgacca cagctgctct
     3181 tccggccact gtcctttggt tgcgggttca taagccagac ctttaccttt cgacatgccg
     3241 taggtggttt tcataccagg gattccgcac tgcacgcgga tggctttgaa tcccagctcc
     3301 tgatgacggg cataatcatc cagagcttca tcaatactgt gaccggtggt atggcaataa
     3361 accatcaccc cttcacgaga cgcgccgccg agtaactggt aaagcggcat gttggcagct
     3421 ttggctttaa tatcccacag cgccatatca accgctgaaa tggccgacat cgtaaccgga
     3481 ccgcgacgcc agtaagcacc tttatagaaa aactgccaga tatcttcgat acggtgcgca
     3541 tcgcgaccaa taagctgcgg acaaaggtga tcctgcaaat aagaggccac ggaaagctca
     3601 cgtccattga gggtggcatc cccaaggccc gtaataccgt cctcagtggt gatttttaat
     3661 gtgacgaaat tacgccccgg acaggtaaca aaaacttcag cctttacgat cttcatgttc
     3721 gattccttgc atcgcttgtc gtgatgcatg aaatctacgc aactgagcta ctaccataca
     3781 agtatggaga tcgaaaaaag ccggagtgat cacaaaaaaa ggcgtatatt tgcgctgtga
     3841 atggttgaca aaagatgaaa tagaatacct tttgtcagct gacacttcct cttatcttat
     3901 tgataaaatg gatttatgtt cctacgtgcg cccccagccc gcaacaatga tcaacatgcc
     3961 gcaaagcgca atcaacgcac ccgtccagtc ataaagagtc agtttcacgc catccacaac
     4021 gcgcagccac atcaacgccg tgcagacata aacgccacca taagccgcgt aaacacgccc
     4081 actcgccgct ggatgcaacg ttaacaacca gacaaacagc gccagtgaaa tccccgccgg
     4141 aagcaacagc cagatactgg cgtttcgttt taaccacaac cagggcagaa agcatccaat
     4201 aatttcacac agcgcagtag caaaaaatag taacgttgtt ttaatcatct ttgtcactta
     4261 ttgacatcat gtatagttat agggcgacat aatatcatca atataaacac cctcctggta
     4321 cgttttgcgt tcgcagtgga tggtgtagaa tctcctttaa tcattcatac agggaatgaa
     4381 ttatgaaaat cactctcagc aaacgaatcg gcctgctcgc ttttctgctg ccttgcgcac
     4441 tggcactgag cacaactgtt catgccgaaa ctaacaaact ggtgattgag tctggcgaca
     4501 gtgcacaaag ccgccagcac gccgctatgg aaaaagagca atggaatgac acgcgcaatc
     4561 tgcgtcagaa agtgaataaa cgcactgaaa aagagtggga taaagccgac gccgcttttg
     4621 ataaccgcga taaatgtgag caaagcgcca acatcaatgc ctactgggag ccaaatactt
     4681 tgcgctgcct ggaccgtcga actggccgcg ttattacccc ctaacctgtt attgatttaa
     4741 ggaatgtaag gacacgttat gccaagcgcc cacagtgtta agctacgccc gctggagcgt
     4801 gaagatttac gctatgtaca tcaactcgac aataacgcca gtgtgatgcg ttactggttt
     4861 gaggaaccct acgaagcctt tgttgaactc tctgatctgt atgataagca tattcacgat
     4921 cagagcgaac gacgctttgt ggtggaatgt gacggcgaaa aagccggtct ggtggagctg
     4981 gtggaaatta accatgtaca tcgccgggca gaatttcaga taattatctc cccggagtat
     5041 caggggaaag gtctggcaac ccgtgccgcc aaattagcaa tggactatgg cttcaccgtt
     5101 ctcaatctct ataagctgta tctgatcgtc gataaagaga atgaaaaagc gattcacatt
     5161 taccgcaagc ttggctttac ggttgaaggt gaattgatgc acgagttctt tattaatggt
     5221 caatatcgta atgccattcg catgtgtata ttccagcatc agtatctggc agagcacaaa
     5281 acaccgggtc agactctcct gaagccgacc gcacaatagc attaataata atcgatcgta
     5341 tttttgatgg tgtaaacccg ttcgacggcg ggttttactc cttcatcaac aatgatcagc
     5401 tgacagtcca ccggattggc gtgactgtca tattcacagc tctgttttac attaccaact
     5461 cgttgattat tcagtaaagt aaccgctgtg taatctaatt ttttgatcgg atccgttgat
     5521 ggcgtggcgc tgacagataa tgttttgtcg ttacttttcg tggttttacc cagcggataa
     5581 ccctgatcat catagcgata ttccatctgc atttgtttgc tgctggcttt aatcacgaag
     5641 ccattatcat cggtttccca actcaccccg gcagaaggta attctgctag ctggcatttt
     5701 ccctgtaaac gtactctctt ctccagcgtc tcggcatcac ggtaataatt ggcgtccagt
     5761 accagagcga ccacggtatt attttccaga tccagtaatt cgagtgaatc aaaacagcct
     5821 tcttccgaca aagtcccaga aacacgtttc gtcacttcac cttgctcatc cattaatgtc
     5881 tgagtgaaat cttttaccgg accacgcagc ggatcaaaat cgaattcatt agagaaactg
     5941 gccatctcag gggtaaatga aagtgttacc tctgtgcggt cacatcctgt gaggaatatc
     6001 gcgagtaagc atggtagtaa tttgtatttc acaacagtca ccagagagta gagatgattc
     6061 tcaatcatag tagcaaatac agtactttac acgttaaatg ctatgcttaa agaagttatc
     6121 ttcgcgtaag gagcttatga tgaaactctc aacctgctgt gccgcgcttc tgctcgccct
     6181 cgcctcaccc gcggtactcg ccgcgccggg atcctgtgag cgcatacaga gcgatatatc
     6241 acagcgcatt atcaataatg gcgtacccga aagcagcttc acgttaagta ttgtacccaa
     6301 tgaccaggtt gatcagcctg attcccaggt cgtcgggcat tgtgctaatg atacgcataa
     6361 aattctctac acccgcacca ccagcggtaa cgtctctgct cccgcgcagt ctacccagga
     6421 tggcgcgcct gccgaaccgc agtaatacat tatcgactga acgccggata cgacacatcc
     6481 ggcgatttga acatacaaca taatcccacc ttattactca tacccttcta ttgatatgga
     6541 ttaataattc
//
LOCUS       DAPGUL010000191         6469 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.195, whole genome shotgun sequence.
ACCESSION   DAPGUL010000191 DAPGUL010000000
VERSION     DAPGUL010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6469
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.195"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..1070)
                     /locus_tag="RHX21_004484"
     CDS             complement(<1..1070)
                     /locus_tag="RHX21_004484"
                     /EC_number="2.7.7.13"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019725197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate
                     guanylyltransferase/mannose-6-phosphate isomerase"
                     /protein_id="HDV1989569.1"
                     /translation="MLLPVIMAGGTGSRLWPMSRELYPKQFLRLFGQNSMLQETITRL
                     SGLEIHEPMVICNEEHRFLVAEQLRQLNKLSNNIILEPVGRNTAPAIALAALQATRYG
                     DDPLMLVLAADHIINNQSAFHDAIQVAEQYADEGHLVTFGIVPNAPETGYGYIQRGVA
                     LTDSAHSAYQVARFVEKPDRERAGVYLASGEYYWNSGMFMFRAKKYLIELAKYRPDIL
                     EACQAAVNAADNGSDFINIPHNIFCECPDESVDYAVMEKTADAVVVGLDADWSDVGSW
                     SALWEVSPKDEQGNVLSGDAWVHNSENCYINSDEKLVAAIGVENLVIVSTKDAVLVMN
                     RERSQDVKKAVEFLRQNQRSEY"
     gene            complement(1350..1634)
                     /locus_tag="RHX21_004485"
     CDS             complement(1350..1634)
                     /locus_tag="RHX21_004485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989570.1"
                     /translation="MSRLSHLSEHSADVVCIGPSNLNTRGLLGGEDDVSSYLSPRRKR
                     SFLTVAGIGWAPVALFSVAVRAYVLPCVIEKVLMVNPAANAESVVRLAAR"
     gene            complement(1827..2132)
                     /locus_tag="RHX21_004486"
                     /pseudo
     CDS             complement(1827..2132)
                     /locus_tag="RHX21_004486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1-like element IS1A family transposase"
     gene            complement(2194..2991)
                     /gene="istB"
                     /locus_tag="RHX21_004487"
     CDS             complement(2194..2991)
                     /gene="istB"
                     /locus_tag="RHX21_004487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element IS21 family helper ATPase
                     IstB"
                     /protein_id="HDV1989571.1"
                     /translation="MHELEVLLSRLKMEHLSYHVESLLEQAAKKELNYREFLCMALQQ
                     EWNGRHQRGMESRLKQARLPWVKTLEQFDFTFQPGIDRKVVRELAGLAFVEHSENVIL
                     LGPPGVGKNHLAIALGVKAVDAGHRVLFMPLDRLIATLMKAKQENRLERQLQQLSYAR
                     VLILDEIGYLPMNREEASLFFRLLNRRYEKASIILTSNKGFADWGEMFGDHVLATAIL
                     DRLLHHSTTLNIKGESYRLKEKRKAGVLTKNTTPISDDEMVKSGQHQ"
     gene            complement(2991..4162)
                     /gene="istA"
                     /locus_tag="RHX21_004488"
                     /pseudo
     CDS             complement(2991..4162)
                     /gene="istA"
                     /locus_tag="RHX21_004488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000952428.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
     gene            complement(4264..4658)
                     /locus_tag="RHX21_004489"
                     /pseudo
     CDS             complement(4264..4658)
                     /locus_tag="RHX21_004489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
     gene            5059..6063
                     /locus_tag="RHX21_004490"
     CDS             5059..6063
                     /locus_tag="RHX21_004490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase"
                     /protein_id="HDV1989572.1"
                     /translation="MKFLVTGAAGFIGFHIAQRLLNEGHDVVGIDNMNDYYDVSLKQA
                     RLDRLASPAFHFQQLDLADREGMAKLFAVEQFDRVIHLAAQAGVRYSLENPYAYADAN
                     LMGYLNILEGCRHTKVKHLVYASSSSVYGLNRKMPFSTEDSVDHPVSLYAATKKANEL
                     MAHTYSHLYGIPTTGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFT
                     YIDDIVEAVVRVQDVIPQANADWTVENGSPATSSAPYRVYNIGNSSPVELMDYITSLE
                     EALGMEAKKNMMPIQPGDVLDTSADTQPLYDLVGFKPQTSVKEGVKNFVEWYKDYYQI
                     "
BASE COUNT         1537 a         1763 c         1591 g         1578 t
ORIGIN      
        1 ttgtactcgc tgcgctggtt ctgcctgagg aactcgaccg ccttcttcac gtcctgggaa
       61 cgctcgcgat tcatcaccag cacggcgtcc ttagtgctga caatcaccag attctctacg
      121 ccaatggccg ccaccagctt ctcgtcgctg ttgatgtagc agttttcgct gttgtgcacc
      181 cacgcgtcac cgctgaggac gttaccctgc tcgtctttcg ggctgacctc ccacagggcg
      241 gaccaggagc cgacgtcgct ccagtcggca tcgagaccga ccaccaccgc gtcggcggtt
      301 ttctccataa cggcgtagtc cacggactca tccgggcact cgcagaaaat attatgtggg
      361 atattgatga aatcgctgcc attatcggcg gcattcaccg cagcctggca ggcttccagg
      421 atatccggac ggtatttggc cagctcgatg aggtatttct tggcgcggaa cataaacatg
      481 ccgctgttcc agtagtactc cccggaggcg aggtagaccc cggcgcgctc gcgatccggc
      541 ttctccacaa agcgggccac ctggtaagcg gaatgggcac tatcggtgag cgccacgccg
      601 cgctgaatgt aaccgtagcc agtttccggg gcattcggca cgataccgaa ggtgaccaga
      661 tgaccttcat cagcatactg ctcggcgacc tggatagcgt cgtggaaggc cgactggtta
      721 ttgatgatat ggtcggcggc gagaaccagc atcagcgggt cgtcaccgta gcgggtggcc
      781 tgaagggccg ccagggcgat ggccggcgcg gtgttgcgcc cgaccggctc aagtataatg
      841 ttattcgaca gcttattgag ctggcgcagc tgttcagcca ccaggaaacg atgctcttcg
      901 ttacagatga ccatcggttc atggatttca aggcccgaga gtcgggtgat agtttcctgc
      961 agcatggagt tctgcccgaa cagacggagg aactgtttcg ggtaaagctc gcgagacatc
     1021 ggccagagac gactgccggt accgccagcc ataattacag gaagtaacat aatgagatcc
     1081 ttaaataaat aattgcttta ttttactatc aatcaatcga ccgtcaggtg gcgtggcctt
     1141 tttgaggcac gctaccgcca ttggctgtcg caaccaaaat gcgtactgct cccgtgctcc
     1201 aggctaagcg ccaccctctt tcgcttcagg ctgtcggcag atcgttcagt cagcagctac
     1261 aatgacagcc tgacggaatg cgtgtcctga aaacctaaaa gcagagatat accttcaggc
     1321 atatctctgc ttttaacatg tatcttccct cacctagccg ccaaacgcac cacactttcc
     1381 gcatttgccg ccgggttaac catcaggact ttctcaatta cgcagggcaa aacgtatgcc
     1441 cttaccgcca ccgaaaaaag cgcaacgggc gcccagccga taccggcaac cgtcagaaag
     1501 gagcgtttac gacgtgggga aagataagaa gagacatcgt cttcaccgcc aaggagacca
     1561 cgcgtattca ggtttgatgg ccctatgcac acaacatcgg cgctatgttc cgacaggtgg
     1621 gataaacgac tcatgcctct acactgcaca ttccacaaag aaaatcgtgc gcagattata
     1681 gcgctggtcg gcgggaataa aaataaaaaa gcctactgat taatggatta ctcaaatgac
     1741 acacaccata aacattcatt aaacaagcaa aaaaagagca atttgttgat atcaatgaag
     1801 aaaagaaagc cggtaatgac tccaacttat tgatagtgtt ttatgttcag ataatgcccg
     1861 atgactttgt catgcagctc caccgatttt gagaacgaca gcgacttccg tcccagccgt
     1921 gccaggtgct gcctcagatt caggttatgc cgctcaattc gctgcgtata tcgcttgctg
     1981 attacgtgca gctttccctt caggcgggat tcatacagcg gccagccatc cgtcatccat
     2041 atcaccacgt caaagggtga cagcaggctc ataagacgcc ccagcgtcgc catagtgcgt
     2101 tcaccgaata cgtgcgcaac aaccgtcttc cggtgtcaac gccacgatgt ttgaccgtta
     2161 tttgccattt tcatgcccgc taagatactt tcgttactga tgctgtccgc ttttcaccat
     2221 ttcatcatca ctgattggcg ttgtgttttt ggtcagcact ccagctttac gtttctcttt
     2281 taaccggtaa ctctctcctt tgatattcag cgtggttgag tgatgtagca accgatccag
     2341 tatagctgtt gccagcacgt gatctccgaa catttctccc cagtctgcga accctttgtt
     2401 tgacgtcagt atgatgctcg ctttttcata tcgacggttc agtagccgga agaacaggct
     2461 ggcttcctct ctgttcatcg gcagatagcc tatttcatcc aggatcaaca cccgggcata
     2521 actcagttgc tgcagctgac gctccagccg gttttcctgt ttcgctttca tcagtgtcgc
     2581 gatcagtctg tccagtggca taaacagtac ccgatgtccc gcatccaccg ctttcacgcc
     2641 aagagctatg gccagatgat tttttccgac accaggaggt cccagcagga tcacgttttc
     2701 gctgtgctcc acgaacgcca gaccagccag ttcccggaca accttacggt cgatgcccgg
     2761 ctggaaggta aagtcgaact gctccagcgt tttgacccac ggcagacgag cctgcttcag
     2821 cctggactcc ataccgcgct gatgcctgcc gttccattcc tgctgtagcg ccatgcacag
     2881 gaactcccgg tagttcagct cttttttagc tgcctgttcc agcaggcttt caacgtgata
     2941 actcagatgc tccattttca ggcgactcag caggacttcc agctcatgca tcacaacagc
     3001 tcctcatagg cactcagtgg tcgatgttcc acctgactga cctgctgcca gagcggggcg
     3061 tgatgctccg gcactgtctg ccagccagac gatgccgaac agaggcgatg tgaggccacc
     3121 agtttctcat tactgtagat ccgcaactcg tcatccagcg atattcgtat cgataccggc
     3181 tgaccacaca gcgcttcggg aacgctgtaa cgattaccac caacctcgat atagctgtcc
     3241 caggacacat ggcggatatc gaagtaactg gtatcgaagt ccgtatccgg taacgactgc
     3301 agatgttcct gctccagcgc gaagtgctgt tccggcgttt ctttgaactg gcgaagttcc
     3361 cgtttgtcag ccacatcggc tatccattgc tccagttgtt gattaacatg agtgaagctg
     3421 tcgaacctgc ggtaccggac gaagaagttc tccttgaggt atttcaccat tcgctcaacc
     3481 ttaccttttg ttctggccct gcgtggacgg catgcccgtg gcaggaagtt atagtggtcg
     3541 gccagcaaca ggaatccgga gttgaacacg actttcccgt tgttattctt cagcaccgca
     3601 gccttctggt tatcaaccag caccgttttc acacaaccac cgaagtagcg gaaggcgcga
     3661 accagtgatt cgtaggtatg ctcagcatcc tgttttggtg ctgcgaagac atggaagcgg
     3721 cgggagaacc ccagcgtatt aaccgcaaag ttaactttgc accgttgccc ggcaacctcc
     3781 acctcaactt cgccccagtc gtgctggagc tggtatccag gctgagtttc gaagcgaact
     3841 gttctttttg acggacgcat tttacgtttg ggctggatgt agtaacgcag catggaacgt
     3901 ccgcccgtat aacccattgc cttaatctcc gcgaagataa cctcactatt ccagacattc
     3961 tctgccaggc gcatgtcgat gtaatccata aacggtttca gcttaaccat tttgtggcgg
     4021 gtctttctgg ctggcggttc agggtatttg aggtagcgtc tgaccgtccg ttcaagcaac
     4081 caatctgagt cgcaatatcg acaatgtacg cgccctgctg gcgcatttac tttatcatgt
     4141 aaaagtcctc tctgctcagc atgttgatgt cctttctggt gtgagaacct taaggaaaca
     4201 acatgttggg tggagcggac aatccaaatg gtgaattacc gtcttatatc actggcgctg
     4261 acaccggaga ctgtcatacg cgtaaaacag ccagcgctgg cgcgatttag ccccgacata
     4321 gccccactgt tcgtccattt ccgcgcagac gatgacgtca ctgcccggct gtatgcgcga
     4381 ggttaccgac tgcggcctga gttttttaag tgacgtaaaa tcgtgttgag gccaacgccc
     4441 ataatgcggg cagttgcccg gcatccaacg ccattcatgg ccatatcaat gattttctgg
     4501 tgcgtaccgg gttgagaagc ggtgtaagtg aactgcagtt gccatgtttt acggcagtga
     4561 gagcagagat agcgctgatg tccggcggtg cttttgccgt tacgcaccac cccgtcagta
     4621 gctgaacagg agggacagct gatagaaaca gaagccactg gagcacctca aaaacaccat
     4681 catacactaa atcagtaagt tggcagcatc accaagaaag ccatcattgc gaacttttag
     4741 cccgtttgat aaataaaccg ggcacaaaaa atataacttt aaacaaactt atgccgggct
     4801 caatgggtat ttgttgcctt tgtgtttagc cacaaatcgc taaaccgctg acaagttaca
     4861 aggttattat ttgcatgcta acagtcaaat gagaaacgtt gttatttatc accttttgcc
     4921 acggttattt tgccagaaaa aacgtccttc acctcacgtc tggcggagat gacgcggcaa
     4981 agcaagtgat cccaaccgca atccagtgta aaatcggcac ttatgtagaa cgggatatcc
     5041 acaccccgga ggaaaaatat gaagtttttg gtcactggtg ccgcaggttt tatcggcttt
     5101 catatcgcgc agcgcctgct gaatgaaggg catgatgttg tcgggatcga caacatgaac
     5161 gactattatg acgtcagcct gaagcaggcc cgtctggatc gcctggcatc tccggcattc
     5221 catttccagc agctggatct ggccgaccgg gaaggtatgg caaagctgtt cgccgtagag
     5281 caatttgatc gcgtgatcca cctggcggct caggccggtg tgcgttactc gctggaaaat
     5341 ccgtatgcct atgcggacgc taacctgatg ggttatctga acattctgga aggctgccgc
     5401 cataccaaag tgaaacacct ggtgtacgcc tcctccagct cggtttacgg cctcaaccgt
     5461 aaaatgccgt tctccaccga agattccgtc gatcatccgg tctccctgta tgccgctacc
     5521 aagaaagcca atgagctgat ggcgcatacc tattcccatc tgtacggcat cccgactacc
     5581 ggcctgcgct tctttacggt ctatggtccg tggggacgcc cggatatggc gctgttcaag
     5641 ttcacgaaag cgatgctgga agggaaaagt attgacgttt acaactacgg caaaatgaag
     5701 cgcgacttca cctacatcga cgacatcgtc gaggcagtgg tgcgcgttca ggatgtgatc
     5761 ccgcaggcca atgctgactg gaccgttgag aacggttccc cggcgaccag ctcagcgccg
     5821 tatcgggtct ataacattgg caacagctcg ccggtggaac tgatggacta catcacctct
     5881 ctggaagagg cgctggggat ggaagcaaag aaaaatatga tgccgattca gccgggcgat
     5941 gtgctggaca ccagcgcaga cacccagccg ctgtatgacc tggtgggttt caagccacag
     6001 acgtcagtga aggaaggggt gaaaaacttc gtcgagtggt ataaggatta ctatcagatc
     6061 taacctgtct ctgccctgcc gcgatcagct gattgcggca atggataaac ctcccgtatt
     6121 cccttcattg atcattcatt tctttacccg agcctggcac aggctatact tttttgtgct
     6181 aaagaataat ttttactggt tttaacgacg gtgctgaaac tagtttcatc tacccgtcag
     6241 cgaaaaagcc aacaacttta agcctggttc cctgcagtca ctcttttcaa tactattttt
     6301 aatggctcct tcagcatttt ctcctgataa ataaaagaca ttactttctg taggaatttt
     6361 cttaagaaca ggatatgtta gagatcgcaa tacagcacct tccacgctga tatattgctt
     6421 aacttgctaa tgattcaacc aactaaagct gtggtagata ttatggaaa
//
LOCUS       DAPGUL010000192         6255 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.196, whole genome shotgun sequence.
ACCESSION   DAPGUL010000192 DAPGUL010000000
VERSION     DAPGUL010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6255
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.196"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(461..592)
                     /locus_tag="RHX21_004491"
                     /pseudo
     CDS             complement(461..592)
                     /locus_tag="RHX21_004491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612086.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            874..2232
                     /locus_tag="RHX21_004492"
     CDS             874..2232
                     /locus_tag="RHX21_004492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase-like activity of phytase family
                     protein"
                     /protein_id="HDV1989573.1"
                     /translation="MKRKIIPVLIGCTLSFSALAAQPTAERYVVSFPEGTHVNYAGAF
                     ASAFPNGLPVGIGSGLLFTGKQGDALTFATITDRGPNADSPKEGKNETKIFVTPDFAP
                     LLMTIRVQNGKAEAIDPRPLHDDKGAINGLPLASDVIGSTNEVAFSDTLHRLKGDNRG
                     LDTEGITPDGKGGYWLCDEYGPFLINIDSKGKILAIHGPQAAEGEKAIAGGLPNILKW
                     RQANRGFEGLTRMPDGRIIVAVQSTLDIDAKSKKKALFTRLVSFDPASGKTAMYGYPI
                     DSAAYSKNSDAKIGDIVALDNQHILLIEQGRDKNNRMRNLIYEVDLNKASDLSGFDKP
                     GEYPEFDDEKTLSQRGITLAQKTQVVDLRSLGWQQEKAEGLALIDSKTLAVANDNDFG
                     VKVAMQHPVEGKTFKDYRVNAEGKLTLDDKQVETTLRVKPLEKPESDSELWIVTLPEA
                     LK"
     gene            complement(2471..3856)
                     /locus_tag="RHX21_004493"
     CDS             complement(2471..3856)
                     /locus_tag="RHX21_004493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HDV1989574.1"
                     /translation="MNDISSDDIFLLKQRLAEQEALIHAQQEKLSNREREIDHLQAQL
                     DKLRRMNFGSRSEKVSRRIAQMEADLNRLQKESDTLTGRVYDPAVQRPLRQTRTRKPF
                     PESLPRDEKRLLPAAPCCPNCGGSLSYLGEDTAEQLELMRSAFRVIRTVREKHACTQC
                     DTIVQAPAPSRPIERGIAGPGLLARVLTSKYAEHTPLYCQSEIYGRQGVELSRSLLSG
                     WVDACCRLLSPLEEALHGYVMTDGKLHADDTPVQVLLPGNKKTKTGRLWAYVRDDRNA
                     GSALAPAVWFAYSPDRKSIHPQTHLACFSGVLQADAYAGFNELYRNGGITEAACWAHA
                     RRKIHDVHVRIPSALTEEALEQIGQLYAIEADIRGMPAEQRLAERQRKTKPLLKSLES
                     WLREKMKTLFFGSGHGGERGALLYSLIGTCKLNDVDPESYLRHVLGVIADWPVNRVSE
                     LLPWRIALPAE"
     gene            complement(3906..4253)
                     /gene="tnpB"
                     /locus_tag="RHX21_004494"
     CDS             complement(3906..4253)
                     /gene="tnpB"
                     /locus_tag="RHX21_004494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019104956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HDV1989575.1"
                     /translation="MIPLPSGTKIWLVAGITDMRNSFNGLAAKVQTALKDDPMSGHIF
                     IFRGRSGSQVKLLWSTGDGLCLLTKRLERGRFAWPSARDGKVFLTQAQLAMLLEGIDW
                     RQPKRLLTSLTML"
     gene            complement(4250..4630)
                     /locus_tag="RHX21_004495"
     CDS             complement(4250..4630)
                     /locus_tag="RHX21_004495"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HDV1989576.1"
                     /translation="MQKNVTPGRRKGCPNYPPEFKQLLVAASCEPGISISKLALENGI
                     NANLLFKWRQQWREGKLLLPSSESPQLLPVTLDAAAEQPESLAEDPETLSISCEVTFR
                     HGTLRFNGNVSEKLLTLLIQELKR"
     gene            complement(4985..5419)
                     /locus_tag="RHX21_004496"
     CDS             complement(4985..5419)
                     /locus_tag="RHX21_004496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001556209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HDV1989577.1"
                     /translation="MRILNCYMANDSKGHFVTAKEAAKHNRQDVLCCVSCGCPLTLQR
                     GNDGQPPWFEHDQMTVAEKILLRCTWLDPAEKEARRLHLQGMTVPDYTVKVRKWFCVM
                     CDEDYEGEKCCPRCGTGVYSRAWGRQEVPSEDARADNPLQRL"
     gene            complement(5407..5808)
                     /locus_tag="RHX21_004497"
     CDS             complement(5407..5808)
                     /locus_tag="RHX21_004497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004020115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989578.1"
                     /translation="MYAKSFIALDGNGRLTGARTAQAAPYANYTCHLCGSALRYHPQY
                     ETELPWFEHTDDRLTEHGQQCPYVRPERREIQLIKRLQQFVPDALPVVRKASWHCRQC
                     HHDYYGEQYCTHCQTGGFSIPRTTQEEICEF"
     gene            complement(6068..>6255)
                     /locus_tag="RHX21_004498"
     CDS             complement(6068..>6255)
                     /locus_tag="RHX21_004498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="inovirus-type Gp2 protein"
                     /protein_id="HDV1989579.1"
                     /translation="ALGVDVGCHATLVHFPAWPAVWLARNDDTGFQQVLERADYLAKE
                     HTKAHCTGERNFGCSRS"
BASE COUNT         1468 a         1684 c         1641 g         1462 t
ORIGIN      
        1 ttctgtgagc gtgaaataat aaacaacaag aacataataa agaagctgat gttctttttg
       61 tcagatgtta atcacaccaa gaaagatgtt gttcagagcg cacttaatat tatcattgac
      121 attacatcag gtgatatttg agattttaca taaaagataa tctctcaagg agtcttatct
      181 gaaaacgaaa tatatagtcc ctctcgtttt gtaatatcga ttggctttgt tgaatcggtt
      241 acgtaccccg gagccggtca tattttcagg taatacacac gctttcagac atttcggctt
      301 tcgtcatttt tgtatcatgg gcatagcttc tgctacctga ccatcataat cacgcagctt
      361 cagtgaagca gtgaccacct gtttaacccg gtgtatcgtt atgatcttat ccagcaattg
      421 aaccgccccg ggtttcctgg agagtgtttt atctgtgaac tcaggctgcc agatcatcgt
      481 ttccgatgga agcataataa gctttttctg cttctgccgg tgggatatgg ccctgccttt
      541 ccagcaatcg tcgattgtta taccagtcca cccacgtgag tgtggtcagc tcatcatact
      601 gacacgtgca ttacccctac cgcgataatg caaccgtaca atatagggcg tttcctaaac
      661 gcagccctca tcactccaat ccaacaagac acagcatttt tgatcacgaa gaaagacaaa
      721 taatttccgt aaatgtttcc gttgttacaa ataacaacag tgttttacat ttctttggcc
      781 tcaggcccgc gcatgttgcc attcgatgtc attttcctga ctcgtttctt ctttatggtg
      841 tagtgtgatc ttcactttat ggatgctaac aatatgaaaa gaaaaattat tcccgtgcta
      901 atcggttgta cgctctcttt ctctgccctg gcggcacaac ctacggctga gcgctatgtc
      961 gtcagttttc cagaaggcac gcacgtgaac tacgccggcg catttgccag tgcattcccg
     1021 aacggccttc cggttgggat aggttctggc ctgctgttca ccggtaaaca gggcgatgcc
     1081 ctgacattcg caaccattac cgatcgcggt ccgaacgcgg attcaccgaa agaggggaaa
     1141 aacgaaacta aaattttcgt tacgccagat ttcgcgccgc tgctgatgac gattcgtgta
     1201 caaaacggca aagcggaggc catcgatccc cgtcctctgc atgacgataa aggcgcgatc
     1261 aacggtctgc cgctggcaag cgacgtgatt ggctccacca atgaagtggc cttcagcgac
     1321 acgttacata gactgaaggg ggataatcgc gggctggata cggaagggat cactccggat
     1381 ggtaaaggag gttactggct gtgcgatgag tatggcccgt tcctgattaa catcgacagt
     1441 aaagggaaaa tcctggcaat ccacggtccg caggcggcgg aaggggaaaa agcgattgcg
     1501 ggcggtttgc caaatatcct caaatggcgt caggcgaacc gcggctttga aggcctcacc
     1561 cgtatgccgg acgggcgtat tattgtcgcc gtgcaaagta cgctggatat cgacgctaag
     1621 agcaagaaaa aggcgctgtt tacgcgtctg gtgagcttcg atccggcaag cggaaaaacc
     1681 gcgatgtacg gttatcctat cgacagcgcg gcctacagca aaaacagcga cgctaaaatc
     1741 ggagacatcg tggcgctcga taaccagcac atcctgctga tcgaacaggg aagagataaa
     1801 aacaacagaa tgcgtaacct gatttacgag gtcgatctca ataaggcgag cgacctgtca
     1861 ggcttcgaca agccgggtga gtatccggag tttgatgatg agaaaaccct gtcacagcgc
     1921 ggcattaccc ttgcgcagaa aacgcaggtt gttgatctgc gctccttggg ctggcagcag
     1981 gagaaggctg aagggttggc gctgatcgac agcaaaacgc tggcggtggc gaacgataac
     2041 gactttggcg tgaaggtggc gatgcaacat ccggtcgagg gcaagacatt caaggattat
     2101 cgggtgaacg cggaaggaaa gctgacgctt gacgacaagc aggttgaaac gaccctcaga
     2161 gtgaagccac tggagaaacc ggagtctgac agtgaactgt ggattgtgac gctgccggaa
     2221 gcgttgaaat aagtttataa ggtacggaca gcagtatcgc ttagtttttc aaattcatgt
     2281 atgtgaacaa tattggggtt ccggcgtaga cccccaatga aagcgtcacc acgtgaaaac
     2341 atgcctgcac ggtttacacg tcatcccatg gtggcagccg gttaactttc ctgcgccacc
     2401 agtggaaaaa ggccataagc agtccgaaca aaagtaagcg tacagcgagg gccgtattga
     2461 cggggatgtg ttattcagct ggcagtgcta tgcgccacgg aagcagttcg ctgacccggt
     2521 tgaccggcca gtctgctatg acgccaagca catggcgaag gtagctttct ggatccacgt
     2581 cattcagttt gcacgtcccg atcaggctgt acagtagcgc tccccgctca ccaccatggc
     2641 cagagccgaa gaacagggtc ttcatctttt cacgcaacca gctttccagg gatttcaaca
     2701 gcggtttcgt ttttcgctga cgttcagcaa gccgctgctc tgccggcatt ccccttatat
     2761 ccgcctctat ggcgtacaac tgaccgatct gctccagggc ttcttccgtc agtgctgacg
     2821 ggatgcggac gtgcacatcg tggatctttc ggcgggcatg agcccagcag gcagcttccg
     2881 ttatcccacc attgcgatac agctcgttga acccggcgta cgcatccgct tgcagcacac
     2941 cgctgaagca agcaagatga gtctgcggat ggatgctttt tctgtccggg ctgtaagcga
     3001 accacactgc aggtgccaac gctgacccgg cattgcggtc atcacgaaca tacgcccaca
     3061 accgcccggt cttcgtcttc ttattacccg gcagcagtac ctggaccggg gtatcatcgg
     3121 catggagttt gccgtcagtc atgacatagc catgaagcgc ctcttccagc ggagacagca
     3181 gccggcagca tgcatccacc cagcccgaca gcagtgaacg gctcagctcc acaccttgcc
     3241 ggccgtatat ttctgactgg caatacagcg gggtgtgctc tgcatacttc gaggtcagca
     3301 cgcgggccag cagccccggt ccggcgatac cccgctcgat gggccgcgaa ggtgcaggtg
     3361 cctgcacgat ggtatcgcac tgagtacagg catgtttttc ccgtaccgtc cggataaccc
     3421 ggaaggcgct acgcatcaac tccaactgtt cggcggtatc ctcgcccaga tagctcagtg
     3481 aaccgccgca gttcgggcag cacggcgccg caggcaacag tcgcttttcg tcacggggta
     3541 gtgattcagg gaacggctta cgggtgcggg tctgacgcaa cggacgctgt actgccgggt
     3601 catacaccct accagtcagc gtatcgctct ctttctgaag ccggttcaga tcggcttcca
     3661 tttgtgcgat acggcgggag actttttcgg aacgactgcc gaagttcatc cggcggagtt
     3721 tatccagctg cgcctgcaga tggtctattt cgcgctcccg gttgctcagc ttttcctgct
     3781 gggcgtggat cagcgcttcc tgttcggcca ggcgctgttt cagcaggaag atgtcgtcag
     3841 aagagatgtc gttcataagc ccgtatttta ccgggcttat tctgtgacaa ccaggataaa
     3901 gagatttaca gcatggtcag ggaggtcagc agccgcttgg gctgtcgcca gtcgatacct
     3961 tccagcagca tcgccagctg cgcctgcgta aggaacactt tgccatcacg ggctgacggc
     4021 caggcgaagc gcccacgctc cagccgtttg gtcaggaggc acagtccgtc gccggtggac
     4081 cacagcagtt taacctgact gccgctgcgg ccccggaaaa tgaaaatatg gccggacatg
     4141 ggatcgtctt tcagcgccgt ttgtactttc gcagccaggc cgttgaagct atttctcata
     4201 tcggtgatac cggcaaccag ccaaattttg gtcccggaag gtaacgggat catcgcttca
     4261 gttcctgtat cagcagagtc aggagctttt cgctgacatt gccattgaag cggagcgtcc
     4321 cgtgccggaa cgttacctca cagctgatac tgagggtttc cgggtcctct gcgagcgatt
     4381 ctggctgttc ggcagctgca tcgagagtca caggaagtag ctgggggctc tctgaagaag
     4441 gtaatagcag ctttccctcg cgccattgtt gtcgccattt gaacaacaga ttggcgttaa
     4501 tgccattttc aagagcaagt tttgagatgg atatcccggg ttcacaggag gcagcaacga
     4561 gcagctgttt aaattcggga ggataattag ggcagccttt tcgcctgccg ggagtcacat
     4621 ttttctgcat atctgacact ttggttccca ctacttattt ggtggacacc actttgtcta
     4681 attcgtcaga ttctgaccag acggttcagg ctgtacgctt accactattt tatccctgtt
     4741 gaatttggtt aagccggtgc agacgcgccg ggaaacgcac acctgaaccg gcacaataaa
     4801 atacaataca accccctgtt actggagata cgaatggaat gacgaggcag cctgtcagtc
     4861 acagggggct gttggcataa aatcaacgga aaggccacca acaccggaat taagctccac
     4921 agtccccgca ctggcaatcc attcccggga aaggcatcac cgcaaactgc tccggaggca
     4981 accattacag cctctgtaac ggattatcag ccctggcatc ttccgacggc acctcctgcc
     5041 gcccccacgc cctgctgtat accccggtac cgcagcgtgg gcagcacttt tccccctcat
     5101 aatcttcgtc acacatcaca caaaaccact ttctcacctt caccgtataa tccggaaccg
     5161 tcatgccctg cagatgcaaa cgacgggcct ctttctctgc cgggtcaagc caggtacatc
     5221 gcagcaggat tttttcagcg acagtcatct ggtcatgttc aaaccacggt ggttgtccgt
     5281 cattgccccg ctgaagtgtt aacgggcatc cacaggacac acagcacaaa acgtcctgtc
     5341 ggttgtgctt cgcagcttct ttcgccgtaa caaaatggcc tttgctgtca ttcgccatat
     5401 aacagttcag aattcgcata tttcctcctg agttgtccgg ggaatactga atcctccggt
     5461 ctggcagtgt gtgcagtact gctccccata ataatcgtgg tgacattgtc tgcagtgcca
     5521 gctggcttta cgcaccacgg gtaaggcatc cggtacgaat tgctgcagac gtttaatcaa
     5581 ctgtatttct ctgcgctccg gcctgacata agggcactgt tgaccgtgct ctgtcagcct
     5641 gtcgtcagtg tgttcaaacc agggaagttc agtttcgtat tgcggatggt atctgagtgc
     5701 actgccacac aagtggcagg tgtagttagc ataaggtgcg gcctgtgcag tacgggcgcc
     5761 cgtcagacgt ccgttgccat caagagcgat aaaggatttt gcgtacatag tcatatacct
     5821 cagccgccag acgacacgca ggcaacagcc gtcccggtac gggcagcgtg gtcagggtgt
     5881 gaatggcggt tcagttaaaa tctggactgg agtttgggta aagcaggctg gttgctgtta
     5941 cagcactgtg gttgtcacac aatggaacac tgacgtaaaa aacagtcagt gggcgagtgg
     6001 atacatcgtt gccgccagac aacaacccat acttttggtt tgccggatat tggcgcgcca
     6061 gtcgtgctca actccggcta cagccaaaat tgcgctcacc ggtgcagtga gctttggtat
     6121 gctccttcgc cagatagtca gcacgttcca gcacttgctg aaagccggtg tcatcattac
     6181 gcgccagcca caccgccggc caggccggaa aatgcaccag cgtggcatgg cacccgacat
     6241 ccactcccag ggcac
//
LOCUS       DAPGUL010000193         6230 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.197, whole genome shotgun sequence.
ACCESSION   DAPGUL010000193 DAPGUL010000000
VERSION     DAPGUL010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6230
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.197"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..1021
                     /gene="nrfB"
                     /locus_tag="RHX21_004499"
     CDS             <1..1021
                     /gene="nrfB"
                     /locus_tag="RHX21_004499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="phage adsorption protein NrfB"
                     /protein_id="HDV1989580.1"
                     /translation="LWLNFGLMVNRIVQRVIFVTGYYGLTQGLLSVLRLFWGNLINFM
                     ANWRALKQVLQHGDPRRVAWDKTTHDFPSVTGDTRSLRPLGQILLENQVITEEQLDTA
                     LRNRVEGLRLGGSMLMQGLISAEQLAQALAEQNGVAWESIDAWQIPSSLIAEMPASVA
                     LHYAVLPLRLENDELIVGSEDGIDPVSLAALTRKVGRKVRYVIVLRGQIVTGLRHWYA
                     RRRGHDPRAMLYNAVQHQWLTEQQTGEIWRQYVPHQFLFAEILTTLGHINRSAINVLL
                     LRHERSSLPLGKFLVTEGVISQETLDRVLTIQRELQVSMQSLLLKAGLNTEQVAQLES
                     ENEGE"
     gene            1008..3980
                     /gene="nfrA"
                     /locus_tag="RHX21_004500"
     CDS             1008..3980
                     /gene="nfrA"
                     /locus_tag="RHX21_004500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage adsorption protein NfrA"
                     /protein_id="HDV1989581.1"
                     /translation="MKENNLNRVIGWSGLLLTSLLSTSALADNIGTSAEELGLSDYRH
                     FVIYPRLDKALKAQKNNDEATAIREFEYIHQQVPDNIPLTLYLAEAYRHFGHDDRARL
                     LLEDQLKRHPGDARLERSLAAIPVEVKSVTTVEELLAQQKACDAAPTLRCRSEVGQNA
                     LRLAQLPVARAQLNDATFAASPEGKTLRTDLLQRAIYLKQWSQADTLYNEARQQNTLS
                     AAERRQWFDVLLAGQLDDRILALQSQGIFTDPQSYITYATALAYRGEKARLQHYLNEN
                     KPLFTTDAQEKSWLYLLSKYSANPVQALANYTVQFADNRQYVVGATLPVLLKEGQYDA
                     AQKLLATLPANEMLEERYAVSVATRNKAESLRLARLLYQQEPANLTRLDQLTWQLMQN
                     EQSREAADLLLQRYPFQGDARVSQTLMARLASLLESHPYLATPAKVAILSKPLPLAEQ
                     RQWQSQLPGIADNCPAIVRLLGDMSPSYDAAAWNRLAKCYRDTLPGVALYAWLQAEQR
                     QPNAWQHRAVAYQAYQVEDYATALAAWQKISLHDMSNEDLLAAANTAQAAGNGAARDR
                     WLQQAEQRGLGNNALYWWLHAQRYIPGQPELALSDLTRSINIAPSANAYVARATIYRQ
                     RHNVPAAVSDLRAALELEPNNSNIQAALGYALWDSGDIAQSREMLEQAHKGLPDDPAL
                     IRQLAYVNQRLDDMPATQHYARLVIDDIDNQALITPLTPEQNQQRFNFRRLHEEVGRR
                     WTFSFDSSIGLRSGAMSTANNNVGGAAPGKSYRSYGQLEAEYRIGRNMLLEGDLLSVY
                     SRVFADTGENGVMMPVKNPMSGTGLRWKPLRDQIFFLAVEQQLPLNGQNGASDTMLRA
                     SASFFNGGKYSDEWHPNGSGWFAQNLYLDAAQYIRQDIQAWTADYRVSWHQKVANGQT
                     IEPYAHVQDNGYRDKGTQGAQLGGVGVRWNIWTGETHYDAWPHKVSLGVEYQHTFKAI
                     NQRNGERNNAFLTIGVHW"
     gene            3981..4871
                     /locus_tag="RHX21_004501"
     CDS             3981..4871
                     /locus_tag="RHX21_004501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4434 family protein"
                     /protein_id="HDV1989582.1"
                     /translation="MRKFIFVLLTLLLVSPFSFAMKGIIWQPQNRDSQVTDTQWQGLM
                     SQLRLQGFDTLVLQWTRYGDAFTQPEQRALLFKRAAAAQQAGLKLIVGLNADPEFFMH
                     QKQSSAALESYLNRLLAADLQQARLWSAAPGVTPDGWYISAEIDDLNWRSEAARQPLL
                     TWLNNAQRLISDVSAKPVYISSFFAGNMSPDGYRQLLEHVKATGVNVWVQDGSGVDKL
                     TAEQRERYLQASADCQSSAPASGIVYELFVAGKGKTFTAKPKPDAEIASLLAKRSSCG
                     KDTLYFSLRYLPVAHGILEY"
     gene            5054..5815
                     /gene="envY"
                     /locus_tag="RHX21_004502"
     CDS             5054..5815
                     /gene="envY"
                     /locus_tag="RHX21_004502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator EnvY"
                     /protein_id="HDV1989583.1"
                     /translation="MQLSSSEPCVVILTEKEVEVSVNNHATFTLPKNYLAAFACNNNV
                     IELSTLNHVLITHINRNIINDYLLFLNKNLTCVKPWSRLATPVIACHSRTPEVFRLAA
                     NHSKQQPSKPCEAELTRVLLFTVLSNFLEQSRFIALLMYILRSSVRDSVCRIIQSDIQ
                     HYWNLRIVASSLCLSPSLLKKKLKNENTSYSQIVTECRMRYAVQMLLMDNKNITQVAQ
                     LCGYSSTSYFISVFKAFYGLTPLNYLAKQRQKVMW"
BASE COUNT         1571 a         1640 c         1617 g         1402 t
ORIGIN      
        1 gctgtggcta aactttggct tgatggttaa ccgcatcgtg cagcgggtga ttttcgtcac
       61 tggctactac ggtctgacgc aggggctgct atctgtcctg cgtcttttct ggggcaacct
      121 gattaacttc atggccaact ggcgcgcgct aaaacaggta cttcaacacg gcgatccacg
      181 tcgcgtcgcg tgggataaaa caacgcatga cttccccagc gtgactggcg atacccgctc
      241 gttgcgcccg ttaggccaaa ttctgctgga aaatcaggtc atcactgaag aacaactcga
      301 tacagcactg cgtaatcgcg tcgaaggtct acgcctgggc ggttcaatgc tgatgcaggg
      361 gctgattagc gccgagcagc tggcacaggc gctggcagag caaaacggcg tggcgtggga
      421 atccatcgat gcctggcaga tcccgtcctc gctgattgcc gaaatgccag cctccgtagc
      481 gctgcattat gcagtactgc cgctgcgtct ggaaaatgat gagttaattg tcggcagtga
      541 agatggtatt gacccggttt cgctggcggc cctgacgcgt aaagtcggac gcaaagtgcg
      601 ttacgtcatt gttctgcggg gacaaattgt cacggggtta cgtcactggt atgcacgccg
      661 acgcggtcac gatccgcggg caatgttgta caatgcggtt cagcatcagt ggctcacgga
      721 acagcagacc ggtgaaatct ggcggcaata tgtgccgcat cagttcctgt tcgccgaaat
      781 actgaccacg ctcggtcata ttaatcgttc agcaattaac gtgttgttat tgcgccatga
      841 acgcagttct ctgccgctcg gcaagttttt ggtcaccgaa ggcgttatca gccaggaaac
      901 gttggatcgc gtcctgacaa ttcaacgcga attacaagtt tcgatgcaat cactattact
      961 caaagcaggt ttaaacacag aacaggttgc gcaactggag tccgaaaatg aaggagaata
     1021 accttaatcg cgtcatcgga tggtctggtt tactgctgac gtctttattg agtaccagcg
     1081 cactcgcaga caatatcggc accagcgcag aagagctggg gctgagcgat tatcgccatt
     1141 ttgttattta tccccgtctc gataaggcgc tgaaggcaca gaaaaataac gacgaagcaa
     1201 ccgccatccg cgaatttgaa tatatacacc agcaggtgcc ggataatatt ccgctgactt
     1261 tataccttgc ggaagcctat cgccattttg gtcatgatga ccgggcgcgg ctgttgcttg
     1321 aggatcaact gaaacgtcac ccaggagatg cccgacttga gcgcagtctg gcggctattc
     1381 cggttgaagt gaaaagcgtt acgactgttg aagaactgct tgcccagcaa aaagcgtgcg
     1441 acgctgcgcc gaccctgcgt tgtcgcagtg aagtcgggca gaatgccctg cggctggcac
     1501 aattacctgt cgccagagcg caactgaacg atgcgacgtt tgctgcatcg ccagaaggaa
     1561 aaacgctgcg aaccgatctg ctgcaacggg caatctacct gaaacaatgg tcccaggcag
     1621 atacgctata caatgaagca cgccagcaga acacattaag cgcggcagaa cgccgtcagt
     1681 ggtttgacgt gcttcttgcc gggcagctgg acgatcggat cctggcactg caatcacagg
     1741 ggatcttcac cgatcctcag tcatatatta cttacgcgac cgcgctggct tatcgtggcg
     1801 aaaaagcacg cctccagcat tatctcaatg aaaataagcc gctgtttacc acggacgcac
     1861 aagagaaaag ttggctctat ctgttatcta aatacagcgc caaccccgtt caggcattgg
     1921 cgaattatac ggtgcagttt gccgataacc gccagtatgt tgttggcgcg acgctaccgg
     1981 tgctgttaaa agaaggtcag tacgacgcag cgcaaaaact gctcgccacc ctccccgcca
     2041 atgaaatgct tgaggagcgt tatgctgtca gcgtggcgac ccgtaacaag gctgaatctc
     2101 tgcgtctggc acgattgctg tatcagcaag aaccggcaaa tcttacccgc ctggatcaac
     2161 tgacctggca actgatgcag aacgagcagt cacgcgaagc tgccgattta ttgctgcaac
     2221 gctatccttt ccagggcgat gcgcgtgtca gccagacttt aatggcgcga ctggcgtctc
     2281 tgctggaaag tcatccttac ctggcaacgc cggcgaaggt ggcgatttta tcgaaaccct
     2341 taccgctggc ggagcaacgt cagtggcaaa gtcagttgcc gggtattgca gataattgcc
     2401 cggcaatagt tcgcttgctg ggcgatatgt cgccttccta cgatgctgcc gcctggaacc
     2461 gtctggcaaa gtgttatcgg gacacgctac ccggtgtggc gctgtatgca tggcttcagg
     2521 ccgaacaacg acaaccgaac gcctggcaac atcgtgcggt agcctatcag gcgtatcagg
     2581 ttgaggacta cgccaccgca ctggcggcct ggcagaaaat cagtcttcac gacatgagca
     2641 atgaggatct gcttgctgct gccaataccg cccaggcggc aggaaatggt gcagctcgcg
     2701 atcgctggct acaacaggca gaacaacgtg gactgggaaa caatgccctc tactggtggc
     2761 tgcatgcgca acgttacatt cctggtcagc cggaactcgc actgagcgat ctcacgcgct
     2821 caatcaatat tgcgccttct gccaacgctt acgttgcgcg ggcgacaatt tatcgccaac
     2881 gtcataatgt cccggcggcg gtgagtgatt tgcgcgccgc gctggaactg gaaccgaata
     2941 atagcaacat ccaggcagcg cttggttacg ccttgtggga tagcggtgat atcgcacagt
     3001 cgcgggaaat gctcgaacag gcgcataaag ggcttccgga cgatccggca ctgatccgac
     3061 aactggccta cgtgaaccag cgtctggatg acatgcctgc gacgcagcac tacgcccggc
     3121 tggtgattga tgacattgat aatcaggcgc tgataacccc actgacccca gagcaaaatc
     3181 agcaacgctt caatttccgc cgtttgcatg aggaggtcgg tcgccgctgg acgttcagtt
     3241 tcgattcttc tatcggcttg cgttccgggg caatgagcac cgctaacaat aatgtcggcg
     3301 gcgcagcgcc agggaaaagc tatcgtagct acgggcaact ggaagccgag taccgcatcg
     3361 gacgcaatat gctgctggaa ggcgacctgc tctcagttta tagccgcgtc tttgccgata
     3421 ccggagaaaa cggggtgatg atgccggtga aaaatccgat gtccggcacc ggtctgcgct
     3481 ggaagccgct gcgcgatcag atctttttcc tcgccgtcga acagcagttg ccgctgaacg
     3541 ggcaaaatgg cgcatccgat accatgctgc gcgccagcgc ctcattcttt aatggcggca
     3601 aatacagcga cgaatggcac ccgaacggtt caggctggtt tgcccaaaac ctgtacctcg
     3661 atgcggcgca atatatccgc caggatattc aggcgtggac ggcagattat cgcgtcagct
     3721 ggcatcagaa ggtagctaac ggacagacta ttgagcctta cgctcacgtt caggacaacg
     3781 gctatcgtga taaaggcact cagggcgcgc agcttggcgg agtcggggtc cgctggaata
     3841 tctggaccgg cgagacgcac tacgacgcct ggccgcacaa agtcagtctc ggcgtcgagt
     3901 atcaacatac ctttaaggcg attaatcaac gtaacggaga gcgcaacaac gcgtttctca
     3961 ccattggagt gcactggtaa atgcgtaagt tcattttcgt attgctgaca ctgcttttgg
     4021 tcagcccttt ttcctttgcg atgaaaggta ttatctggca accacaaaac cgagatagtc
     4081 aggttaccga tacccagtgg caggggctga tgagtcagtt acgtttgcaa ggcttcgata
     4141 ccctggtttt gcaatggacc cgttacggcg atgcattcac ccagccagaa cagcgcgcgt
     4201 tattgtttaa gcgtgccgca gctgcgcaac aggctggcct gaagctgatt gtcgggctga
     4261 acgccgatcc ggaatttttt atgcaccaga aacagtcgtc cgcagcgctg gaaagctatc
     4321 ttaatcgcct gctggctgcc gatctccagc aagccagatt atggagcgcc gcgcctggcg
     4381 taacgccgga tggctggtac atcagcgcgg aaattgacga cctgaactgg cgcagcgaag
     4441 ctgcccgtca gcctttgcta acatggttaa acaacgcgca gcggctgatt agcgatgttt
     4501 cagcaaaacc ggtttatatc agtagttttt tcgccggaaa catgtcgccc gatggctatc
     4561 gccaactgct ggaacacgtt aaagcaaccg gcgttaatgt ttgggtacag gatggcagcg
     4621 gcgtggataa actgaccgct gaacagcgtg aacgttatct acaggccagc gccgattgcc
     4681 aaagttccgc cccagcaagc ggcattgttt atgaactgtt tgtcgccggc aaaggcaaaa
     4741 cctttacagc gaaaccgaaa ccggacgcag agatcgcctc gctgttagcg aaacgttcct
     4801 cttgcggtaa agacactctc tatttctctc tgcgctattt gcccgtcgcg cacggcattc
     4861 tcgagtatta aatctcctcc aggtaagtcg ggtacgacct ggcttacctc tttcgctctc
     4921 gtcagaattc catcaagatt aattgctaaa aagcgtgcta aagaaagaag atcgttatcg
     4981 gcgaacgggc cgatcactca tgcaggaagc atagatcctt tgagcggagt ttctgatatc
     5041 tgaggagtgc gaaatgcaat tgagcagcag tgaaccttgc gtggtgatcc tgaccgaaaa
     5101 agaggtagag gtaagcgtca ataaccatgc tacgtttacc cttccgaaaa actacctggc
     5161 cgccttcgcg tgcaacaata acgtcattga actctcaacg ttaaatcacg tattaatcac
     5221 ccacatcaac cgtaacatca tcaacgatta tctgttgttt ttaaataaga acttaacctg
     5281 tgtaaagccc tggtcgcggc tggcaacccc ggttattgct tgtcatagcc gtacaccgga
     5341 agtgttccgg ctagccgcca accacagcaa gcagcaaccc agcaaaccct gcgaagcgga
     5401 gttgacgcgc gtattgcttt ttaccgtatt gtctaacttt cttgagcaat cgcggtttat
     5461 tgccctactg atgtatatct tacgcagcag cgtccgcgac agcgtctgcc gcattattca
     5521 aagcgatatt cagcattact ggaatctgcg aattgtcgcc agttcgctat gtttaagccc
     5581 cagcctgctc aaaaagaaat taaaaaacga aaataccagc tatagccaga ttgtcacaga
     5641 gtgtcgtatg cgttacgccg tacagatgtt attgatggat aacaaaaata tcactcaggt
     5701 ggcgcaatta tgtggctata gcagcacgtc atactttatc tctgttttta aggcgtttta
     5761 cggcctgaca ccgttgaatt atctcgccaa acagcgacaa aaagtgatgt ggtgaagggc
     5821 aaagcggaaa cggataagac gggcataaat gaagaagaaa tggcgcgccc tgcaggattc
     5881 gaacctgcgg cccacgactt agaagttcct agaacgacat tttaagtcaa caaattaccg
     5941 cgccatctct gcgctcacac gtcccactac ctcaaaacat gtaaagcctt gcaagccatt
     6001 gtgaggcctt atgtgtctca gttttgtccc tcttttttgt actaaaaaac atagcaattg
     6061 aggataaacc tcatgctatt ttcgcttata tgcctttaaa ggcatggcgc ttaaatagat
     6121 aaaaacacca caaaagcata aaaaaccaca cagtaaaacc gcaacataaa acaataacag
     6181 ataattaaac caaaaacaga tagcgcattg tgataatcat tcaatactaa
//
LOCUS       DAPGUL010000194         6134 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.198, whole genome shotgun sequence.
ACCESSION   DAPGUL010000194 DAPGUL010000000
VERSION     DAPGUL010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6134)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6134)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6134
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.198"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            79..855
                     /gene="exuR"
                     /locus_tag="RHX21_004503"
     CDS             79..855
                     /gene="exuR"
                     /locus_tag="RHX21_004503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ExuR"
                     /protein_id="HDV1989584.1"
                     /translation="MEITEPRRLYQQLAADLKERIEQGVYLVGDKLPAERFIADEKNV
                     SRTVVREAIIMLEVEGYVEVRKGSGIHVVSNQPRHQQAADNNMEFANYGPFELLQARQ
                     LIESNIAEFAATQVTKQDIMKLMAIQEQARGEQCFRDSEWDLQFHIQVALATQNSALA
                     AIVEKMWTQRSHNPYWKKLHEHIDSRTVDNWCDDHDQILKALIRKDPHAAKLAMWQHL
                     ENTKIMLFNETSDDFEFNADRYLFAENPVVHLDTATSGSK"
     gene            1200..1862
                     /locus_tag="RHX21_004504"
     CDS             1200..1862
                     /locus_tag="RHX21_004504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HDV1989585.1"
                     /translation="MELLTQLLQALWAQDFETLANPSMIGMLYFVLFVILFLENGLLP
                     AAFLPGDSLLVLVGVLIAKGAMGYPQTILLLTVAASLGCWVSYIQGRWLGNTRTVQNW
                     LSHLPAHYHQRAHHLFHKHGLSALLIGRFIAFVRTLLPTIAGLSGLNNARFQFFNWMS
                     GLLWVLILTTLGYMLGKTPVFLKYEDQLMSCLMLLPVVLLVFGLAGSLVVLWKKKYGN
                     RG"
     gene            1866..2249
                     /gene="mzrA"
                     /locus_tag="RHX21_004505"
     CDS             1866..2249
                     /gene="mzrA"
                     /locus_tag="RHX21_004505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EnvZ/OmpR regulon moderator MzrA"
                     /protein_id="HDV1989586.1"
                     /translation="MQIPRMSLRQLAWSGTVLLLVGTLLLAWSAVRQQESTLAIRAVH
                     QGTTMPDGFSIWHHLDAHGIPFKSITPKNDTLLITFDSSDQSAAAKAVLDRTLPHGYI
                     IAQQDNNSQAMQWLTRLRDNSHRFG"
     gene            2396..2764
                     /locus_tag="RHX21_004506"
     CDS             2396..2764
                     /locus_tag="RHX21_004506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1090 domain-containing protein"
                     /protein_id="HDV1989587.1"
                     /translation="MKYRIALAVSLFALSAGSYATTLCQEKEQNILKEISYAEKHQNQ
                     NRIDGLNKALSEVRANCSDSQLRADHHKKIAKQKDEVAERQQDLAEAKQKGDADKIAK
                     RERKLAEAQEELKKLEARDY"
     gene            2802..3107
                     /locus_tag="RHX21_004507"
     CDS             2802..3107
                     /locus_tag="RHX21_004507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF883 domain-containing protein"
                     /protein_id="HDV1989588.1"
                     /translation="MSKEHTTEHLRAELKSLSDTLEEVLSSSGEKSKEELSKIRSKAE
                     QALKQSRYRLGETGDAIAKQTRVAAARADEYVRENPWTGVGIGAAIGVVLGVLLSRR"
     gene            3110..3514
                     /locus_tag="RHX21_004508"
     CDS             3110..3514
                     /locus_tag="RHX21_004508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDV1989589.1"
                     /translation="MADTHHAQGPGKSVLGIGQRIVSIMVEMVETRLRLAVVELEEEK
                     ANLFQLLLMLGLTMLFAAFGLMSLMVLIIWAVDPQYRLNAMIATTVVLLLLALIGGIW
                     TLRKSRKSTLLRHTRHELANDRQLLEEESREQ"
     gene            3504..3803
                     /locus_tag="RHX21_004509"
     CDS             3504..3803
                     /locus_tag="RHX21_004509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqjK-like family protein"
                     /protein_id="HDV1989590.1"
                     /translation="MSSKVERERRKAQLLSQIQQQRLDLSASRREWLEATGAYDRRWN
                     MLLSLRSWALVGSSVMAIWTIRHPNMLVRWARRGFGVWSAWRLVKTTLKQQQLRG"
     gene            3989..4381
                     /locus_tag="RHX21_004510"
     CDS             3989..4381
                     /locus_tag="RHX21_004510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008503138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HDV1989591.1"
                     /translation="MKKLEDVGVLVARILMPILFITAGWGKITAYSGTQQYMEAMGVP
                     GFMLPLVILLEFGGGLAILFGFLTRTTALFTAGFTLLTAFLFHSNFAEGVNSLMFMKN
                     LTISGGFLLLAITGPGAYSIDRLLNKKW"
     gene            4451..5437
                     /gene="yqjG"
                     /locus_tag="RHX21_004511"
     CDS             4451..5437
                     /gene="yqjG"
                     /locus_tag="RHX21_004511"
                     /EC_number="1.8.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708909.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionyl-hydroquinone reductase YqjG"
                     /protein_id="HDV1989592.1"
                     /translation="MGQLIDGVWHDTWYDTKSTGGKFQRSASAFRNWLTADGAPGPTG
                     TGGFIAEKDRYHLYISLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSF
                     PGATGDTLYQHEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAF
                     DALGAKAGDYYPPALQTKIDELNGWIYDTVNNGVYKAGFATSQQAYDEAVAKVFESLA
                     RLEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRD
                     IYQMPGIAETVNFDHIRNHYFRSHKTINPTGIISIGPWQDLDEPHGRDVRFG"
     gene            5730..6095
                     /locus_tag="RHX21_004512"
     CDS             5730..6095
                     /locus_tag="RHX21_004512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HDV1989593.1"
                     /translation="MDWYLKVLKNYVGFRGRARRKEYWMFILVNIIFTFVLGLLDKML
                     GWQRAGGEGILTTIYGILVFLPWWAVQFRRLHDTDRSAWWALLFLIPFIGWLIIIVFN
                     CQAGTPGENRFGPDPKQEP"
BASE COUNT         1533 a         1517 c         1546 g         1538 t
ORIGIN      
        1 atttatatat gaccaatggc atacccatga ataaagtggt atgataactt cgtccgcatt
       61 ccactccggg agacgcatat ggaaatcact gaaccacgcc gtttgtatca acaacttgcc
      121 gctgacctga aagagcgcat cgaacagggc gtctatctgg taggtgataa actgcctgca
      181 gaacgcttta ttgccgatga aaagaacgtc agccgtacgg tagttcgtga agccatcatc
      241 atgctggaag ttgaaggcta tgtcgaagtg cgtaaaggtt caggtattca tgtggtttcc
      301 aaccagccgc gccatcagca ggcggctgac aataatatgg aattcgccaa ttacggtccg
      361 tttgagttgc ttcaggctcg ccagctcatc gaaagtaata ttgccgagtt cgcggcaact
      421 caggtaacga aacaagacat catgaaactg atggccattc aggaacaggc gcgcggcgaa
      481 caatgcttcc gtgattccga gtgggattta cagttccaca ttcaggtagc cctggcgacg
      541 cagaactccg ccctggcggc catcgttgaa aaaatgtgga cccaacgtag ccataacccg
      601 tactggaaaa aactgcacga acacattgat tcccgtaccg tcgataactg gtgtgatgac
      661 cacgatcaaa tcctcaaggc gctgattcgc aaagatcctc atgctgctaa gctggcaatg
      721 tggcagcacc tggaaaacac caagatcatg ttattcaacg aaaccagcga cgacttcgag
      781 ttcaatgccg accgctatct gttcgccgaa aacccggtag tgcatctcga tacggccacc
      841 agtggcagta aatgaaactc ctgtccgaca ggcgctgcga cgcgcctgtt tgtctcgtcg
      901 gtaagcgaaa agtataaagt gtcagcctgt gtaaatcctc tcgccaccct cccctgcatt
      961 cagcaaaatc agactccacg gacatgtaat tttgataacg aacaacgttg acctttgtta
     1021 caattagatt caatttgaat ttatgttttt gaatgctttc ttatctcacg atttaacagg
     1081 gaatagttca ggctgtgttg atgtatcaaa cccgcagaac ataccaaaac agcaataaca
     1141 ttgcggtagt gcatctttta aaaccagcgt ggcgttaacc gattcaccag gaataatgaa
     1201 tggaactttt gacccaattg ctgcaagccc tgtgggcgca ggattttgaa accctggcca
     1261 atccatcgat gattggcatg ttgtattttg tcttgtttgt aattttgttc cttgaaaacg
     1321 gcttgcttcc agcggccttt ttaccgggcg acagtttact ggtattggtc ggcgtgttga
     1381 ttgcgaaagg cgcgatgggt tacccgcaaa cgattctgct gctgaccgtt gccgccagcc
     1441 tcggctgctg ggtcagctat attcaggggc gatggctggg caatacccgc accgtacaaa
     1501 actggctatc tcatttaccc gcgcattatc atcaacgcgc acaccatctt tttcataaac
     1561 acggtttatc ggcgctgtta attggtcgct ttattgcgtt tgtcagaaca ctgctgccga
     1621 cgattgccgg gttatcaggg ctgaataacg cgcgctttca gtttttcaac tggatgagcg
     1681 gtctgctgtg ggtattgatc ctgacaactc tgggttacat gctcggcaaa acgccggtat
     1741 ttttaaagta cgaggaccag ctgatgtcat gcctgatgct gctcccggtg gtgctgctgg
     1801 tgtttggcct ggcaggttct ctggtcgtgt tatggaaaaa gaaatatgga aatcgggggt
     1861 aagggatgca aatacctcgc atgtcgcttc gccagctagc ctggtccggc actgttttac
     1921 ttctggtcgg cacgctgttg ctggcctggt ccgcggttcg ccagcaagag tctacgctgg
     1981 cgattcgtgc cgttcatcaa ggcacaacga tgccagacgg tttttcgatc tggcatcacc
     2041 ttgacgctca tggcattcct ttcaaaagta tcacccccaa aaacgacact ctgttaatta
     2101 catttgactc cagcgaccag agcgccgccg caaaagcggt cctcgacaga acattgcccc
     2161 atggctacat cattgcgcag caggacaata acagtcaggc tatgcagtgg ctgacccggt
     2221 tacgggataa ctctcatcgc ttcggataac ttcctgttat ccgaaacata tcactcactt
     2281 tggtgatttc accgtaactg tctatgatta atgaggcggt ggttaacact accgcttcgt
     2341 tgtctggaca atcgttcctt tgtaataggt ccgaatcaca atggaaggtt caagaatgaa
     2401 ataccgcatc gctttagctg tttctctctt tgctcttagt gccggtagtt atgccactac
     2461 cctgtgtcag gaaaaggagc aaaatatcct taaggagatc agctatgccg aaaaacacca
     2521 aaaccagaat cgtattgacg gtctgaataa agccctgagt gaagtccggg ccaactgttc
     2581 agatagccag ctgcgtgccg atcatcacaa gaaaatcgca aagcagaaag atgaggtggc
     2641 ggaacgccag caagatttag ccgaggcgaa gcaaaaaggc gatgccgata agattgccaa
     2701 acgcgaacgg aaactggcag aagcgcagga agagctgaaa aagctggaag cgcgcgacta
     2761 ctaactcaca atagtcacta cttactcacc tggagaaaac tatgtcgaaa gaacacacta
     2821 cggaacatct gcgtgctgag ttgaaatccc tttccgatac gctggaagag gtgcttagct
     2881 catctggcga gaagtcgaaa gaagagttga gtaagattcg tagcaaagcg gagcaggcac
     2941 tgaaacagag ccgttatcgc ctgggtgaaa ccggtgatgc catcgccaaa caaacccgtg
     3001 tcgcggcggc gcgtgctgat gagtatgtgc gtgaaaatcc gtggaccggc gtgggaattg
     3061 gcgctgcaat cggtgtagtg ctcggcgttc tgctgtcgcg tcgttaatta tggcggacac
     3121 tcatcacgcg caagggcccg gtaaaagcgt tctgggcatc gggcagcgaa ttgtttccat
     3181 catggttgaa atggtggaaa cacgtctgcg gctggcggtg gtggagctgg aagaggaaaa
     3241 agctaatctc tttcaacttt tactgatgct gggcctgacg atgcttttcg ctgcatttgg
     3301 tcttatgagc ctgatggtgc taattatttg ggcggttgat ccgcaatatc gcctgaatgc
     3361 gatgattgcc accaccgtgg tgttgctgct actggcactg attggcggta tctggacgtt
     3421 acgtaaatcg cgtaaatcca ccttgctgcg ccatacacgc catgagctgg caaacgatcg
     3481 gcaactgctc gaggaggagt cccgtgagca gtaaagtcga acgtgaacga cgtaaggcgc
     3541 aactgcttag ccagatccag caacaacggc tggatctttc cgccagtcgt cgtgaatggc
     3601 tggaggcaac aggcgcttac gatcgtcgct ggaatatgct gctaagtctg cgctcctggg
     3661 cgctggttgg cagtagcgtg atggcgatct ggacgattcg ccatcctaat atgctggtcc
     3721 gctgggccag acgcggtttt ggcgtatgga gcgcctggcg tctggttaaa acgaccctca
     3781 agcagcaaca gcttcgcggt taacttccct ctggccggag caattccggc cttatccctc
     3841 aaattttttg aagatttttg acagttttcc ttgctaacaa tcatcattca ccacgtttat
     3901 gattctctcc atcgacagca acgacgctaa taccgcgccc ttgcacaaaa aaacaatcag
     3961 cagcctgagt ggcgcagtgg agagtatgat gaaaaaatta gaagatgttg gtgtactggt
     4021 agcgcgcatt ttaatgccga ttctgtttat taccgcaggc tggggaaaaa tcaccgctta
     4081 ctctggtacc caacaatata tggaagcaat gggtgtcccg ggttttatgc tgccgctggt
     4141 gattctgctt gagttcggtg gtggtctggc aatcctgttc ggtttcctga ctcgcaccac
     4201 agccctgttt actgcgggct ttacgctgct gacggcattt ttatttcaca gcaactttgc
     4261 tgaaggcgtc aactcgctga tgttcatgaa aaacctgaca atttctggcg gattcctgct
     4321 gctggcaatt accggtccgg gcgcgtatag catcgaccgc ctgctgaata aaaagtggta
     4381 agcacgcgct atacttaacg ataaaaaacg aggaggaagc tcctcgtttt tgctattgga
     4441 ggagagaaaa atgggtcaac tgattgacgg cgtctggcat gacacctggt acgataccaa
     4501 atctaccggc ggtaaatttc aacgttcagc ttccgcattt cgtaactggc tcactgccga
     4561 tggcgcacct ggccccactg gcacaggcgg ttttatcgca gagaaagatc gttatcatct
     4621 ctatatttca ctcgcctgcc cgtgggcgca ccgcacgctg atcatgcgca aactcaaagg
     4681 actggaaccg tttatttccg tttccgtagt gaacccgctg atgctggaaa acggctggac
     4741 ctttgatgac agttttccgg gagcaaccgg agatacgctc tatcaacatg aatttctgta
     4801 tcagctttat ctccacgccg atccacacta cagcggacga gttactgttc ccgtgctgtg
     4861 ggacaaaaag aaccacacca tcgtcagcaa cgaatcagca gaaatcatcc gcatgttcaa
     4921 taccgcgttt gatgcgctgg gcgcaaaagc gggtgattac tacccaccag ccctgcaaac
     4981 gaaaattgac gaacttaacg gctggattta tgacaccgtt aacaacggcg tgtataaagc
     5041 tggttttgcc accagccagc aagcctacga cgaggcggtg gcgaaagtgt ttgaatcgct
     5101 ggcgcgactg gagcagattt taggccagca tcgttacctg accggcaacc agctaaccga
     5161 agccgatatt cgcctgtgga ccacgctggt ccgttttgat ccagtgtatg tgacccactt
     5221 caagtgtgat aagcaccgca tcagcgatta ccttaatctg tatggcttcc tgcgtgatat
     5281 ctaccagatg ccgggaattg ccgaaacagt caatttcgat cacatccgta atcattactt
     5341 ccgcagccat aagaccatca accctacggg gattatttca attggtccat ggcaggatct
     5401 cgatgaaccg catggacgag atgttcgctt cggttaaaaa aaggcacctt acgaggtgcc
     5461 tctgataatt agctaagtgc atgttgttca tgtcggatgc ggcgtgaacg ccttatcaaa
     5521 cctacaaaac atttatattc aatatgttgc aatgaccgcg caggccagat aagcgtagcg
     5581 catctggcga ttttgcgctt gtcatcagtc ttagcgcgcc ttcacagcac tttattaatt
     5641 ccttgaacga atatttactg ccatttcatt cacgtctatt cttaatttgc tgctttaaaa
     5701 acaagtgatt gagcaaaatt gaggcaaaaa tggactggta tctgaaagta ctaaaaaatt
     5761 atgtcggttt ccggggtcgt gcgcggcgca aagagtactg gatgtttatt ctggtcaaca
     5821 tcatctttac gttcgtgctg gggctgctgg ataaaatgtt aggctggcaa cgcgctggtg
     5881 gcgaaggcat cctgacgaca atctacggta ttctggtgtt tttaccgtgg tgggcagttc
     5941 agttccgccg cctgcacgac accgaccgct cggcgtggtg ggcactgttg ttcttaatcc
     6001 cgtttatcgg ctggcttatt atcatcgtct ttaactgcca ggcgggtacg ccaggcgaaa
     6061 accgctttgg accagatccg aaacaggaac cttaaaacaa atctgctcgc cggatgtctg
     6121 actcatccgg cttt
//
LOCUS       DAPGUL010000195         6079 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.199, whole genome shotgun sequence.
ACCESSION   DAPGUL010000195 DAPGUL010000000
VERSION     DAPGUL010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6079
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.199"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(499..720)
                     /locus_tag="RHX21_004513"
     CDS             complement(499..720)
                     /locus_tag="RHX21_004513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000545700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989594.1"
                     /translation="MHFRKMKVVFLFIHILAVVMISVMTVHLCSMAMEKVPEECDIPV
                     RVAALVVLWLVFSGLIYWLFTAFMKTDVM"
     gene            complement(735..926)
                     /locus_tag="RHX21_004514"
     CDS             complement(735..926)
                     /locus_tag="RHX21_004514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989595.1"
                     /translation="MSDFVRHFSMKDKKEDVVMQDMHFLLEDFICAHISRKSGRVPDR
                     LRQRMDKLRLQRVRKDRTG"
     gene            complement(1039..2070)
                     /gene="f17g"
                     /locus_tag="RHX21_004515"
     CDS             complement(1039..2070)
                     /gene="f17g"
                     /locus_tag="RHX21_004515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F17G fimbrial adhesin"
                     /protein_id="HDV1989596.1"
                     /translation="MTNFYKVFLAVFILVCCNISHAAVSFIGSTENDVGPSQGSYSST
                     HAMDNLPFVYNTGYNIGYQNANVWRISGGFCVGLNGKVDLPVVGSLDGQSIYGLTEEV
                     GLLIWMGDTNYSRGTAMSGNSWENVFSGWCVGNYVSTQGLSVHVRPVILKRNSSAQYS
                     VQKTSIGSIRMRPYNGSSAGSVQTTVNFSLNPFTLNDTVTSCRLLTPSAVNVSLAAIS
                     AGQLPSSGDEVVAGTTSLKLQCDAGVTVWATLTDATTPSNRSDILTLTGASTATGVGL
                     RIYKNTDSTPLKFGPDSPVKGNENQWQLSTGTETSPSVRLYVKYVNTGEGINPGTVNG
                     ISTFTFSYQ"
     gene            complement(2072..4609)
                     /locus_tag="RHX21_004516"
     CDS             complement(2072..4609)
                     /locus_tag="RHX21_004516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001315611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDV1989597.1"
                     /translation="MSHYFLSGLKYRVIYLCCLSGLYMLSVPLWAAEDAEFDPSFLSR
                     TPGSSVIDVRRFTHGNPVPSGNYYSDIYLNGEWKGNAELSFRDMSSSQEESVLCVTPE
                     LLSILDVSPEAVAREPDTGNGRCMPFSAVVPDAKIRFDLSLLRLNVEIPQAMLVSRPR
                     GYISPSQWQTGVPAAFVSYDVNHWRYRTPDMENNQSYLGLRAGFNAGGWAFRHRGTES
                     WSDGHAEGYRSIETNLQHDIAMLRAQLTLGDFTTTGELMDSNSLRGIRLASDDRMLPG
                     SLRGYAPVVRGMAGSNARVTVRQNGNIIYETTVPAGPFSISDLYPSGYGGDLTVTVTE
                     SDGQTRSFIVPFASVAQLVRPGFSRWQVAAGRYRYGNRTFSDTVFQGTLQYGLTNDIT
                     LNTGMSTAPHYLSGLGGVAFNTPLGAVATDITLARTTFPGSDTTHRGYSLHAGYSARI
                     PETSTNVTLAAYRYSSRDFWSLRDAILTRNRDVINDSSVRSATGYRPRNQLQLTVNQS
                     LGEGWGNLYLTGATYHYWGHTGTFNEYQAGYNNVWKKMSYQIGFSQTRRSGDYHHDNR
                     FFFSFSLPLSDTGRTLLSTTVNVSDKNSNSIQSSISGVSGDDNQLSYGVSLNTQENGP
                     TGYAVNGSYRSPVATLQATAGNDSRHNRQISAGISGAIVAHPFGVTASNDLGDTFTVI
                     HADGAGGAVINNAPGNRLDPWGNGIVPYVTPYEKNYISIDPTALAADVELSATEREII
                     PRANSTTMVTFTTKTGKAMLFDVKMQDGTPPPMAAEALTADGKSAGYIAQGGRLFVRD
                     LDAEKGMLRVVWGSGQNDSCVIHYSASGENARGNAVPENHHVVCMRQ"
     gene            complement(4624..5346)
                     /locus_tag="RHX21_004517"
     CDS             complement(4624..5346)
                     /locus_tag="RHX21_004517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016232883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HDV1989598.1"
                     /translation="MKHILLFIFTVLLSLPSYGSVVIMGTRVIYPAEQKSINVRLNNG
                     DSTPSLIQAWLDTGDPSSPPDSVRVPFIITPPVFRVEPLSGQTMRIMYTGEKLPADRE
                     SLFWLNVLDIPAKPSFAGKSEKAQGYNYLQFAVRSRIKFFFRPDGLPFSPDDAYKKVT
                     WQLTGGDTLQASNPTPYFITFSTVSVGQGAQKVSSTQGGMAAPFSSVTFRLKQKVSPS
                     GKVEWTVVNDNGGYQKGESVVK"
     gene            complement(5414..5959)
                     /gene="f17a"
                     /locus_tag="RHX21_004518"
     CDS             complement(5414..5959)
                     /gene="f17a"
                     /locus_tag="RHX21_004518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_021520534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F17A fimbrial adhesin"
                     /protein_id="HDV1989599.1"
                     /translation="MQKIQFILGILAAASSSATLAYDGTINFNGKVVDQTCSVTTAGT
                     APLAVTLPTVSTKSLNSPGKVAGLTPFTISLSGCNTAAATGSQSVKAYFEPNANTDYT
                     TGNLTNTTSSGASNVQIQLLNADGVKVIKLGQAAAAQNVDTVAINDANVTLRYNAQYY
                     ATGVATAGDVTSTVNYTIAYQ"
BASE COUNT         1682 a         1580 c         1289 g         1528 t
ORIGIN      
        1 tgttaccagt aattcttatg ccatcacaag cccaaaaaat cattaataac ccaccccacc
       61 catgcaaata aaagaaaata catttcacat gaaataccat gatatatata ttgcccggag
      121 tgatggtgtt tttatgaagc aatttaaata atacagataa ctgtaattta tcactcagac
      181 gaagagattt gatttacacg gtaagagcat atggcacatt acaacagggg tctctgtgaa
      241 tatatacaga aaacatatct cataaaaccc gggaaatgcc ccatgaatac aggacagtga
      301 aaacaggcat gataatcagg aaagccatgc ctgatacaga aaaagttacc tgcggggata
      361 atgcatgcgt attttcatgg aaggagatca ctcaataact tccatcgaga gcgggtaata
      421 actcaccgat ctccttcacg gtaataagca atgcacaacc aagcacttac tggccggtta
      481 tccatgtcta tattatattt acatcacgtc agttttcata aaggctgtga acagccagta
      541 aatcaggcca ctgaatacca gccacagcac aaccagggct gcaaccctca cagggatatc
      601 acactcttcc ggcacttttt ccatagccat actgcacaga tggactgtca taacagaaat
      661 catcacaaca gcaaggatat gaatgaaaag aaaaacgact ttcattttcc ggaaatgcat
      721 atacaaaccc tgactcagcc tgtcctgtct ttcctgaccc tctgtaatct taacttatcc
      781 atgcgctgac gaagtctgtc cggaacacgc ccgctctttc ttgaaatatg agcacagata
      841 aaatcttcaa gcagaaaatg catgtcctgc attaccacat cttctttttt gtctttcatt
      901 gaaaaatgcc tgacaaaatc gctcatgaaa atgtttctga aacgctgtta tccagcttca
      961 gaaaccggta ctgctttcgc caacgcaaat cattttgtta ttactgtctg acctgctctc
     1021 ccctcccgga actcgctgtt actgatagga aaacgtaaat gttgatattc cgttaaccgt
     1081 acccggatta attccctcac cagtattcac atactttaca tacaaccgga ctgagggtga
     1141 cgtttccgtt cctgtcgata actgccactg gttttcattt ccctttaccg gcgaatcagg
     1201 tccaaacttc aggggcgtac tgtcagtgtt tttgtatatt ctcagcccga ctccggttgc
     1261 agtcgatgcc cccgtcagtg tgagtatatc gcttctgttg gacggtgtgg tcgcatcagt
     1321 cagtgttgcc catactgtta ctccggcatc acactgtaat ttcagtgatg ttgtcccggc
     1381 gacaacttca tcaccggatg atggtagttg tccggcagaa attgcagcca ggctgacatt
     1441 gactgcggaa ggtgtcagta atctgcacga tgttactgtg tcattcagcg taaatggatt
     1501 caggctgaaa ttcactgtgg tctgaacact gcctgcagat gaaccgttat agggcctcat
     1561 tctgatactc ccgatactgg ttttctgtac actgtattgc gcagaggaat ttctttttaa
     1621 aattaccggt cttacgtgaa cagacagtcc ctgcgttgat acataatttc ccacgcacca
     1681 tccggaaaag acattctccc atgagtttcc actcatcgcg gtacccctgg aataattcgt
     1741 gtcccccatc catataagga gtcccacctc ctccgtcagc ccataaatac tctgcccgtc
     1801 aagactgcca accacgggta aatccacttt cccgttcaga ccaacacaaa acccgccact
     1861 aatacgccag acatttgcat tctgatatcc aatgttgtaa ccggtattat agacaaatgg
     1921 caggttatcc attgcatgag tgctggaata agagccctga gacggtccaa catcattctc
     1981 cgtactgcca ataaatgaaa ctgccgcatg gctgatattg cagcaaacca gaatgaatac
     2041 agccagaaag accttataaa aatttgtcat attattgcct catgcatact acatgatggt
     2101 tttccggaac agcatttccc ctggcatttt ctccggacgc actatagtga atgacacaac
     2161 tgtcattctg cccgcttccc cagactaccc tgagcatccc tttttcagca tccaggtcac
     2221 gtacaaataa ccggccaccc tgagcaatgt agcctgcaga tttcccgtct gctgttaatg
     2281 cttccgcggc catcggcggc ggcgttccgt cctgcatctt cacatcaaac aacatggctt
     2341 tccccgtttt tgttgtgaag gtcaccatgg tggtactgtt ggcccgggga ataatttccc
     2401 gctctgttgc agacagttcc acatccgcag ccagcgctgt cgggtcgata ctgatataat
     2461 tcttttcgta aggtgtgaca tacggaacaa tgccgttacc ccaggggtcc agccggttac
     2521 ccggcgcatt attaatcacc gccccaccgg caccatcagc atgaataacg gtaaatgtgt
     2581 caccaaggtc attactggcc gtcacaccaa acggatgcgc cactattgcc ccggatatac
     2641 cggcagatat ctgacggtta tggcgactgt cattacctgc cgtggcctgc agggtggcca
     2701 ccggtgaacg ataactgcca ttcaccgcat accctgtcgg tccgttttcc tgggtgttca
     2761 gggacacacc atatgacaac tgattgtcat ccccgctgac accactgata ctgctctgaa
     2821 tgctgttact gtttttatcg ctgacattca ctgtcgtgga cagcaacgtc cttcccgtat
     2881 ctgaaagtgg cagggaaaaa ctgaaaaaga accggttatc atgatgataa tcaccactcc
     2941 gtcgggtctg ggaaaagcca atctggtaac tcattttttt ccagacgttg ttataaccgg
     3001 cctggtactc attgaatgtc cctgtatgtc cccagtaatg ataagtggct ccggtcagat
     3061 acaggtttcc ccatccctca ccaagactct ggttcacagt cagttgcaac tgattccttg
     3121 gccggtaacc agttgcactc ctgaccgatg aatcattaat cacatcacga ttcctggtca
     3181 ggatggcatc ccgaagactc cagaagtcac gggatgaata acggtaagcc gccagcgtca
     3241 catttgtact ggtttccggt attcgtgcac tgtaaccggc atgcaggctg tagccgcgat
     3301 gtgtcgtgtc agaacccggg aaagtcgttc tggccagcgt aatatccgtg gcaacagccc
     3361 ccagtggtgt gttgaatgcc acaccaccca gccctgacag ataatgaggt gcggtactca
     3421 tccccgtatt cagggtgata tcatttgtca gcccgtactg cagggtcccc tggaatacgg
     3481 tatcgctgaa tgtcctgtta ccgtaacgat aacgcccggc tgccacctgc cagcgactga
     3541 accccgggcg aaccagttgt gcaaccgaag caaacggcac gataaaactc ctggtctgtc
     3601 cgtctgactc tgtcacagtg actgtcaggt caccaccata tccactggga taaaggtcac
     3661 tgatggagaa aggccctgcc ggcacggtag tttcataaat aatgttaccg ttctgccgga
     3721 cagtgaccct ggcgttactt ccggccatcc cccgaaccac aggggcataa ccacgcaacg
     3781 aacccggcag catccggtca tcagaagcca gtcttattcc cctgaggctg ttactgtcca
     3841 taagctcacc tgtggtggtg aaatccccca gtgtcagttg cgcacgcaac atggctatgt
     3901 cgtgctgaag gttcgtttca atactccggt aaccttctgc atgaccgtca ctccagcttt
     3961 ctgtcccccg gtgacgaaat gcccagcctc ctgcgttaaa gccggcacga agaccaagat
     4021 aactctgatt attttccata tcgggcgtcc ggtaacgcca gtgattcacg tcataactga
     4081 caaaggcagc cggcaccccc gtctgccact gagaaggtga tatgtatccc cgtggacggg
     4141 aaaccagcat ggcctgcgga atttcaacat tcagccgcag cagtgacagg tcaaaacgga
     4201 tttttgcatc aggtacaact gcagaaaatg gcatgcaacg gccatttccg gtatccggtt
     4261 cacgggcaac tgcctcgggt gacacatcca gaatggataa cagttccggc gtcacacaca
     4321 gaacactctc ctcctgtgaa gaggacatat cacggaatga caattccgca tttcctttcc
     4381 attcaccgtt cagataaatg tctgaataat aattccctga gggaacagga ttcccgtgcg
     4441 tgaaacgacg gacatcaatc acactgctcc ctggcgtgcg gctcagaaaa ctcgggtcaa
     4501 attctgcatc ctctgccgcc cacaaaggca cagacagcat atacagtccc gacagacaac
     4561 ataaataaat gacacggtac ttcagaccgg ataaaaaata atgactcact tacggggccc
     4621 ttattatttc acaacggatt cgcctttctg gtaaccacca ttatcattca ccaccgtcca
     4681 ttccactttt cctgacggag aaaccttctg cttaagtctg aaagtgacag aagaaaacgg
     4741 tgcggccatt cccccctgag tactgctgac tttctgagct ccctgcccga cactgacagt
     4801 actgaaggta ataaaataag gcgtgggatt actggcctga agggtatcac cgcctgtaag
     4861 ctgccatgtc actttcttat atgcatcatc aggagaaaaa ggcagaccat caggacggaa
     4921 aaaaaactta atccggctgc gtacggcaaa ctgaaggtaa ttatatccct gtgctttttc
     4981 agattttccg gcaaaagaag gtttggccgg aatatcaaga acattcagcc agaacagtga
     5041 ttccctgtct gccggaagtt tttctcccgt atacataatt cgcattgtct gtccggaaag
     5101 cggctccacc cggaaaacag gaggcgtaat aataaacggc accctgacag agtcaggagg
     5161 ggaagacggg tcccctgtat caagccatgc ctgtatcagg gatggcgtac tgtctccgtt
     5221 attcagccgg acattaatac ttttttgttc tgcaggataa ataaccctgg tccccataat
     5281 aaccacactg ccatatgagg gcagagacaa aagaacggta aaaatgaaca gcagaatatg
     5341 tttcatacag gctccgtaaa cacggggcaa aatgccccgt gaacacttaa gaaggcaggt
     5401 attaagataa aaattactga taagcgatgg tgtaattaac tgtagaagta acatcgcctg
     5461 cagtagccac acccgttgcg tagtactgcg cgttataacg caatgtcaca tttgcatcat
     5521 taatagcaac tgtatccaca ttctgagctg cagcagcctg accaagttta ataactttaa
     5581 ccccatctgc attcagtagc tgaatctgaa cattagatgc accagaagaa gtcgtattag
     5641 ttaaattacc agtggtgtaa tccgtgttcg cattaggctc aaaataagcc ttcacacttt
     5701 gagatcctgt agcggcagca gtattacacc cactcagtga aattgtgaaa ggagtaaggc
     5761 ctgctacctt cccgggtgaa tttaatgatt ttgtggagac agttggtagt gtaactgcca
     5821 agggagcggt tcctgctgta gtaacagaac aagtttgatc aacgactttc ccattaaaat
     5881 taattgtacc gtcataagca agcgtagcag aagatgatgc agccgccagt attccaagga
     5941 taaattgaat tttctgcata gaatcctcag tgaaaactga taagaatata tcatgaaaac
     6001 agcagcagtt aagaatttga cttaatatat taagaacaaa tttaattgcc tatataagat
     6061 tatccatagt taaaaaact
//
LOCUS       DAPGUL010000196         5970 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.200, whole genome shotgun sequence.
ACCESSION   DAPGUL010000196 DAPGUL010000000
VERSION     DAPGUL010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5970
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.200"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(1115..1723)
                     /locus_tag="RHX21_004519"
     CDS             complement(1115..1723)
                     /locus_tag="RHX21_004519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989600.1"
                     /translation="MKMKPQYQTRYELLHESYQKWLTGFTRHAVSWGMCHPNIHYFHN
                     LTPGWVSFNGEKPEIAIVPRSLHRLIYGSDKRATPPLDDDLVVNLCTSEHLLVHHPML
                     EGILLSECERLRQRSLANKLISLFRQFGGTELRLKLVWLCWLDLMTGNSLDDWTENLK
                     RKSEKELEEWIIDRQKQNTALTDLMDQYVLLAYRTTVDDNRN"
     gene            complement(1811..2017)
                     /locus_tag="RHX21_004520"
     CDS             complement(1811..2017)
                     /locus_tag="RHX21_004520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
                     /protein_id="HDV1989601.1"
                     /translation="MNTPVSLMDDQMVDMAFITQLTGLTDKWFYKLIKDGDFPAPIKM
                     GRSSRWLKSEVEAWLQARIAQSRP"
     gene            2804..2953
                     /locus_tag="RHX21_004521"
     CDS             2804..2953
                     /locus_tag="RHX21_004521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002208622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin activation protein"
                     /protein_id="HDV1989602.1"
                     /translation="MEKVISHTRYNLTSAELEAFNSAVDHRLAELTMNKLYDRVPASV
                     WKYVT"
     gene            3588..4157
                     /locus_tag="RHX21_004522"
     CDS             3588..4157
                     /locus_tag="RHX21_004522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus Gp2 family protein"
                     /protein_id="HDV1989603.1"
                     /translation="MTYKYNPFWQQRIRETVRHALNVHPRLTALRVDLRLPDVPAATD
                     AAVISRFINALKARIDAYQKRKRREGKRVHPTTLHYAWAREFGELKGKKHYHLLLLVN
                     RDTWCRAGDYRAPGSLAGMIKQAWCSALGVDAGCYATLAHFPDTPAVWLARNDDTGFQ
                     QVLERADYLAKEHTKAHGTGERNFGCSRS"
     gene            4323..4706
                     /locus_tag="RHX21_004523"
     CDS             4323..4706
                     /locus_tag="RHX21_004523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000270954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989604.1"
                     /translation="MYAKSFLALDGNRRLTGARTAQTAPYDRYTCHLCGSALRYHPQY
                     DTERPWFEHTDDGLTAHGQQCPYVRPERREILLIKRLQQWVPDALPVVRKASWHCRQC
                     HHDYYGEQYCTHCHTGHFSEEAVAG"
     gene            4703..5128
                     /locus_tag="RHX21_004524"
     CDS             4703..5128
                     /locus_tag="RHX21_004524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989605.1"
                     /translation="MNGLKTGLGITPGEHIISADSALSRNIRHCFCLSCRGRLILQTD
                     AQGAWFEHDLHALTAQQKTDCVVLNPEKSHPYIDDMAMFLSPLPVVLEWHCVMCGQHF
                     PGKKFCEACGTGIYSRAVCTKYVYSYQPDLFLDCGSAST"
     gene            complement(5393..5722)
                     /locus_tag="RHX21_004525"
                     /pseudo
     CDS             complement(5393..5722)
                     /locus_tag="RHX21_004525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463350.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S16"
     gene            complement(5726..>5970)
                     /locus_tag="RHX21_004526"
     CDS             complement(5726..>5970)
                     /locus_tag="RHX21_004526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDV1989606.1"
                     /translation="MSRRGNCRDNSPMERFFRSLKNEWMPVVGYVSFSEAAHAITDYI
                     VGYYSALRPHEYNGGLPPNESENRYWKNSNSVASFC"
BASE COUNT         1518 a         1442 c         1564 g         1446 t
ORIGIN      
        1 tggtcaataa aaaggcaatc tgcgcgctgt atagtcattc tgacaggaaa tgcaggagga
       61 agggaaggta actggcttcg ttatgctgac aggaatacct gttatcatgg aagtgcattc
      121 atgtggccga cgtagcttaa gaggatggaa gagtggagac tgcagacagg ggggattgaa
      181 aggtaaacat atttcgcccg ccagctgcac cggaggccag catcactttt tttacgttgt
      241 aacccggtat gcattccggc tttgatgatt acagtcagag ggcagcagac tgacgttatt
      301 taaccggaaa gaaaaattat ggacactgaa atatcgtctg ttaatacctc gtttgtcggt
      361 gtggtattcc ctgtattacc ggcatcaccg ataaagagag ttataaacgc cagaaaggta
      421 cctcctttat gccggggaat acttatggaa aatgaagtct gaaaaggagc acaatgaaaa
      481 gagacgtgtc ccgtaaatat aacgaatcat cgcaggatat gcattatcag gtgatgccag
      541 agggcattaa attgtcgtca cggataagaa tatacaacat ttctgataac aaaacatcat
      601 aacgtgtttc agatatgttc cggcatcagt ctgacggata ttatttcccg gtaaaacaaa
      661 ccggctactg taacggttaa ctgtatctgc ataaattatt tatgatgaaa gaacagtatt
      721 acggattcaa atatcatcct gtttgcattc aggcggatat tcccggatgc cggaaagaat
      781 atcctgcagg ctgagtgagt ctcttccaca gtgccgggat cgctgtcgcc acgtacatat
      841 tgtcaccagg atgggtatgt accgcagcat gccatttctg gtgaataacc gcacctgcac
      901 attcagtctg ctgagaacct ggcgtgtatc gggctgtaaa gaacatccct gtccgtggct
      961 cctctggtgg tgttgcctgc tcagcaatga ctggataccc ttaagacatc cgtcatggct
     1021 cagtatgatg acgacgaaca cgtcctgcag gtgagcatgc ggggccggga gcagcatttc
     1081 cgtattttgt cgcaccttcc ggaagcaacc ggcatcagtt acggttatcg tcaaccgttg
     1141 tgcggtatgc caggagcacg tactgatcca tcagatccgt cagtgctgtg ttctgcttct
     1201 gacggtcgat gatccattcc tccagctctt tttctgattt ccgtttcagg ttctccgtcc
     1261 agtcgtcaag gctgtttccg gtcattaaat caagccagca gagccagacc agtttgaggc
     1321 gcagttccgt gccaccaaac tgacggaaga gactgatcag tttatttgcc agcgaacgct
     1381 gcctcagacg ttcacattca gacagcagaa tgccttccag catcggatga tgaaccagca
     1441 gatgttcgct ggtacataag ttcaccacca gatcatcatc caggggcggc gtggcccgtt
     1501 tgtcagagcc ataaatcagc cggtgcagac tccgggggac gatggcaatc tccggttttt
     1561 caccattgaa tgacacccac ccgggcgtca gattatggaa gtagtggata ttcggatgac
     1621 acatgcccca ggatacggcg tgccgggtga agccggtcag ccatttctgg tagctttcgt
     1681 ggagcagctc gtaacgggtc tgatactgtg gtttcatttt catattcctc acgggggata
     1741 acaggcagca gaacgccgcc ggcaggccgg agattgcgtc tgctgtgggt gaaggggcag
     1801 tggttaaaaa ttacggacgg gactgtgcaa tacgcgcctg cagccaggct tccacttcac
     1861 ttttcagcca gcgggagctg cggcccattt tgatgggcgc aggaaagtca ccatccttga
     1921 tgagtttgta aaaccactta tcggtcaggc cggtcagttg agtgataaat gccatgtcga
     1981 ccatctggtc atccatcagt gaaactgggg tattcatgaa aatgttcctc cggatgttgt
     2041 taatcgcaac cggtgtggtg atgaaaacaa cgcaccacct tcaccggcat aacaaccggg
     2101 aagaaacgta aaaaatgagt aggggaatgt tcatgccggg agataaacag ggagcatgat
     2161 gctgagatat ccggtggcta ccgcgaaacg atgcttcccg ctcgtacgag cgataaagaa
     2221 gcgagggact ttcgtgagac aaggggaaaa ctggtgttct gataattgca gagttgtttt
     2281 gaaggcggtg atggtgagtc agcccgtgac ctgtgggcag gcgacaggta tcactggtgg
     2341 gataaggctg tctgattggt attaaatata taagagagag atcaagagag agattaagag
     2401 agagatcaaa cacatgagat caaataattg agttcatata tgtgaaataa acactgtgag
     2461 tgcgatcagt gggccagtct acgcagtagc agcagattgc gttgtaccca cagggctatc
     2521 cctgatagct ggcgtataac ctgcgtatat aaaacgtacc tgcaacccac gtgaacagag
     2581 tgcattaagc atccgtctga gcggtaagcg tatccgacct ggtgagtgac aatctgagag
     2641 accggttaag tgctggcatg ggagtaatga gtttggggag ggtaccagaa tgccagtctg
     2701 gtgcggtatg ctgacagtat cacgttaatt gcagcataaa gtgatgagag gctaatggaa
     2761 gttaaaacca aagcagttcc gtcgttgttc atcccgggag acactggaaa aagtgatttc
     2821 ccacacacgt tataacctta cctctgcgga gctggaagcc ttcaactctg cggtcgatca
     2881 ccggctggca gaactgacaa tgaacaagct ttacgatcgc gtgccggctt ccgtctggaa
     2941 atatgtcacc tgaacgttcg gtaatcacag cggtattgcg ccaggtgtta tctgctctat
     3001 gtgattcttt ttgggttttc tcaggttgtt aaaagctgaa tatgttcctg ttgtcgggaa
     3061 ccaggataat accgggaacg ttaagcggta tagcgacaac aaagaattcg aaatcaaaag
     3121 ggaatggtgt acggaggtgt ggacggtaat gggccgattt tcgggcatta ccgacctctg
     3181 ctgaggtttt ctcgtatttc tggggatccg gtgagttact gtcactgtct ggcacagcaa
     3241 gcgcagaggc ggcggggcgc tttgctccgc tgattccgga taattcctcc cctgtaacct
     3301 accgcaacag tacaaataca ctgacgcctg aaacgacagc cagaatcagc acaagccaca
     3361 atccctgcac accgttttgc gtatcaccat aacgcctcct cacagcctta cccgtaaccg
     3421 gttttttaca ttaaaaaaac aacgctggga attcaatcgt cagtccggag acgacagtcg
     3481 ggttatcaca gagtgcctga gacagtgtcc tgccggaggt cacctcaggg actctgcaca
     3541 ttttttacag cgtggctatt ccgtatgaac catacggaga tttaaccatg acctacaaat
     3601 acaacccctt ctggcagcaa cgtattcgtg agacggtgcg gcacgcactg aatgttcatc
     3661 cccgcctgac ggcattgcgg gttgacctgc gtctcccgga tgtaccggca gcaacggacg
     3721 cagctgtgat atcccgcttc atcaatgccc tgaaagcccg aatcgacgct taccagaagc
     3781 gtaagcgccg tgaaggtaaa cgcgtacatc ccacgaccct gcattacgcc tgggcccggg
     3841 agttcgggga gcttaaaggc aaaaaacact atcacctgct gctgctggtc aaccgggata
     3901 cctggtgtcg tgccggtgat taccgcgctc cggggtcact ggccgggatg attaaacagg
     3961 cctggtgcag tgccctgggg gtggatgccg gatgctatgc cacgctggcg cattttccag
     4021 acacgccggc ggtgtggctg gcgcgtaatg atgacaccgg ctttcagcag gtgctggaac
     4081 gcgctgacta tctggcgaag gagcatacca aagctcacgg caccggtgag cgcaactttg
     4141 gttgcagtcg tagctgagcc cgacagacga gttatctgac ctcagtgtga tgacgcattc
     4201 acgaccatca cactgatttt cccttctgag accggactga aaccgccatt cacacctgat
     4261 cacgctgccc gaaccgggac ggctgttgcc tgcgtgtcgt ctggcggtaa ggaacatata
     4321 ctatgtacgc aaaatctttt ctcgcacttg atggcaacag acgtctgacg ggcgcccgta
     4381 ccgcacagac tgcaccttac gatcgctaca cctgccacct ttgcggcagt gcgctcagat
     4441 accacccgca atacgacacc gaacggccct ggtttgaaca cactgacgac gggctgacgg
     4501 ctcacggtca gcagtgccct tatgtcagac cggagcgcag agaaatacta ttgattaaac
     4561 gcttacagca atgggtaccg gatgccttac ccgtggtgcg taaagccagc tggcactgca
     4621 gacaatgtca ccacgattat tatggggagc agtactgcac acactgtcat acagggcatt
     4681 tcagtgagga ggcagtggca ggatgaacgg tctaaaaacg gggctgggga tcacgccggg
     4741 tgagcacatt atcagtgccg attctgcgct cagcagaaat atcaggcatt gtttctgcct
     4801 ttcctgtcgt ggtcggttga ttttgcagac agatgctcag ggggcgtggt ttgagcatga
     4861 tttacatgcc ctgaccgcgc aacagaagac ggactgcgtg gtgctgaatc cggaaaaatc
     4921 ccatccttac attgatgata tggcgatgtt tttatcgcca ttacctgtcg tgctggagtg
     4981 gcattgtgtg atgtgcgggc agcattttcc cgggaaaaag ttctgtgaag cctgtggcac
     5041 ggggatctat tccagagcgg tatgtacaaa gtatgtttac agctaccagc cagacttgtt
     5101 cctggactgt ggaagtgcga gcacttaatc cgaaatgcct ggtctgcgca gggcgttcaa
     5161 tccaactcga cgaacatctt ccagtgttga attagctgat agctcctcca ttttttgtaa
     5221 agaacagtta tacaggctta tttgaacagc tctcttttta ttcaaacaca gccaacaata
     5281 ctcagatgta agtattttta tattcatgaa tggagaggca aggtctgatg aatttaatta
     5341 cagaacgttc ttgagccatt gtcctctcca gttcattaaa atagttacta cattaattca
     5401 cacccagcgc cttataaaca gcatcaaccg ggtctgagta aaaactcacc tgaaacttgg
     5461 taaataactc tgccggaacc gttggaatat ccatagccga ggacatcggc aacagaactc
     5521 gttttgcgcc gctgtcgaag gcgagctgta aactggcagc aagatcttgt accgggttaa
     5581 ttactccacc aagcgtcata ctgcccaaca ccaccatctg ttcctgtact ggttttgcca
     5641 gcaatatcga acataaagcg ataagcgcag caagactggt tgcggtgctt gggccagtat
     5701 tatgcagttc aacgacatga agtggtcaac aaaaactggc caccgagtta gagtttttcc
     5761 agtatcgatt ttccgattcg tttgggggta acccaccgtt atattcgtgc ggtcttagtg
     5821 cgctgtaata tccaacgata tagtccgtta tggcgtgagc tgcctcgctg aagcttacgt
     5881 aacccaccac cggcatccat tcgttcttca gactcctgaa gaagcgttcc attgggctgt
     5941 tatccctgca gtttccgcgc cggctcatac
//
LOCUS       DAPGUL010000197         5881 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.201, whole genome shotgun sequence.
ACCESSION   DAPGUL010000197 DAPGUL010000000
VERSION     DAPGUL010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5881
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.201"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            163..1557
                     /gene="galP"
                     /locus_tag="RHX21_004527"
     CDS             163..1557
                     /gene="galP"
                     /locus_tag="RHX21_004527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/proton symporter"
                     /protein_id="HDV1989607.1"
                     /translation="MPDAKKQGRSNKAMTFFVCFLAALAGLLFGLDIGVIAGALPFIA
                     DEFQITSHTQEWVVSSMMFGAAVGAVGSGWLSFKLGRKKSLMIGAILFVAGSLFSAAA
                     PNVEVLILSRVLLGLAVGVASYTAPLYLSEIAPEKIRGSMISMYQLMITIGILGAYLS
                     DTAFSYTGAWRWMLGVIIIPAILLLIGVFFLPDSPRWFAAKRRFVDAERVLLRLRDTS
                     AEAKRELDEIRESLQVKQSGWALFKENSNFRRAVFLGVLLQVMQQFTGMNVIMYYAPK
                     IFELAGYTNTTEQMWGTVIVGLTNVLATFIAIGLVDRWGRKPTLTLGFLVMAAGMGVL
                     GTMMHIGIHSPSAQYFAIAMLLMFIVGFAMSAGPLIWVLCSEIQPLKGRDFGITCSTA
                     TNWIANMIVGATFLTMLNTLGNANTFWVYAALNVLFILLTLWLVPETKHVSLEHIERN
                     LMKGRKLREIGAHD"
     gene            1634..2131
                     /locus_tag="RHX21_004528"
     CDS             1634..2131
                     /locus_tag="RHX21_004528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family zinc-dependent metalloprotease"
                     /protein_id="HDV1989608.1"
                     /translation="MKTSRLPIAIQQAVMRRLREKLAQANLKLGRNYPEPKLSYTQRG
                     TSAGTAWLESYEIRLNPVLLLENSEAFIEEVVPHELAHLLVWKHFGRVAPHGKEWKWM
                     MESVLGVPARRTHQFELQSVRRNTFPYRCKCQEHQLTVRRHNRVVRGEAVYRCVHCGE
                     QLVAK"
     gene            2226..2933
                     /gene="endA"
                     /locus_tag="RHX21_004529"
     CDS             2226..2933
                     /gene="endA"
                     /locus_tag="RHX21_004529"
                     /EC_number="3.1.21.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease I"
                     /protein_id="HDV1989609.1"
                     /translation="MYRYLSIAAVVLSAAFSGPALAEGINSFSQAKAAAVKVHADAPG
                     TFYCGCKINWQGKKGVVDLQSCGYQVRKNENRASRVEWEHVVPAWQFGHQRQCWQDGG
                     RKNCAKDPVYRKMESDMHNLQPSVGEVNGDRGNFMYSQWNGGEGQYGQCAMKVDFKEK
                     AAEPPARARGAIARTYFYMRDQYNLTLSRQQTQLFNAWNKMYPVTDWECERDERIAKV
                     QGNHNPYVQRACQARKS"
     gene            3013..3744
                     /gene="rsmE"
                     /locus_tag="RHX21_004530"
     CDS             3013..3744
                     /gene="rsmE"
                     /locus_tag="RHX21_004530"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014226833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HDV1989610.1"
                     /translation="MRIPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFD
                     GSNQVFDAEITSASKKSVEVKVLEGKIDDRESPLHIHLGQVMSRGEKMEFTIQKSIEL
                     GVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWC
                     AEQDEGLKLNLHPRASNSINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLG
                     PRVLRTETTALTAITALQVRFGDLG"
     gene            3757..4707
                     /gene="gshB"
                     /locus_tag="RHX21_004531"
     CDS             3757..4707
                     /gene="gshB"
                     /locus_tag="RHX21_004531"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione synthase"
                     /protein_id="HDV1989611.1"
                     /translation="MIKLGIVMDPIANINIKKDSSFAMLLEAQRRGYELHYMEMGDLY
                     LINGEARAHTRTLNVKQNYEEWFSFVGEQDLPLADLDVILMRKDPPFDTEFIYATYIL
                     ERAEEKGTLIVNKPQSLRDCNEKLFTAWFSDLTPETLVTRNKAQLKAFWEKHSDIILK
                     PLDGMGGASIFRVKEGDPNLGVIAETLTEHGTRYCMAQNYLPAIKDGDKRVLVVDGEP
                     VPYCLARIPQGGETRGNLAAGGRGEPRPLTESDWKIARQIGPTLKEKGLIFVGLDIIG
                     DRLTEINVTSPTCIREIEAEFPVSITGMLMDAIEARLQQQ"
     gene            4816..5379
                     /locus_tag="RHX21_004532"
     CDS             4816..5379
                     /locus_tag="RHX21_004532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgE/AlgH family protein"
                     /protein_id="HDV1989612.1"
                     /translation="MNLQHHFLIAMPALQDPIFRRSVVYICEHNTNGAMGIIVNKPLE
                     NLKIEGILEKLKITPEPRDESIRLDKPVMLGGPLAEDRGFILHTPPSNFASSIRISDN
                     TVMTTSRDVLETLGTDKQPSDVLVALGYASWEKGQLEQEILDNAWLTAPADLNILFKT
                     PIADRWREAAKLIGVDILTMPGVAGHA"
     gene            5379..5795
                     /gene="ruvX"
                     /locus_tag="RHX21_004533"
     CDS             5379..5795
                     /gene="ruvX"
                     /locus_tag="RHX21_004533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HDV1989613.1"
                     /translation="MSGTLLAFDFGTKSIGVAVGQRITGTARPLPAIKAQDGTPDWNI
                     IERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFANRIHGRFGVEVKLHDERLSTVE
                     ARSGLFEQGGYRALNKGKVDSASAVIILESYFEQGY"
BASE COUNT         1393 a         1534 c         1569 g         1385 t
ORIGIN      
        1 ttaatctatg atgatataac tcaattattt tcatgcactt aaaccataac taagataaat
       61 gttagtgtaa gcgattacac tgatgtgatt tgcttcacat ctttttacgt cgtactcacc
      121 tatcttaatt cacaataaaa aataaccata ttggagggca tcatgcctga cgctaaaaaa
      181 caggggcggt caaacaaggc aatgacgttt ttcgtctgct tccttgccgc tctggcggga
      241 ttactctttg gcctggatat cggtgtaatt gctggcgcac tgccgtttat tgcagatgaa
      301 ttccagatta cttcgcatac gcaagaatgg gtcgtaagct ccatgatgtt cggtgcggca
      361 gtcggtgcgg tgggcagcgg ctggctctcc tttaaactcg ggcgcaaaaa gagcctgatg
      421 atcggcgcaa ttttgtttgt tgccggttcg ctgttctctg cggctgcgcc aaacgttgaa
      481 gtactgattc tttcccgcgt tctactgggg ctggcggtgg gtgtggcctc ttataccgca
      541 ccgctgtacc tctctgaaat tgcgccggaa aaaattcgtg gcagtatgat ctcgatgtat
      601 cagttgatga tcactatcgg gatcctcggt gcttatcttt ctgataccgc cttcagctac
      661 accggtgcat ggcgctggat gctgggtgtg attatcatcc cggcaatttt gctgctgatt
      721 ggtgtcttct tcctgccaga cagcccacgt tggtttgccg ccaaacgccg ttttgttgat
      781 gccgaacgcg tgctgctacg cctgcgtgac accagcgcgg aagcgaaacg cgaactggat
      841 gaaatccgtg aaagtttgca ggttaaacag agtggctggg cgctgtttaa agagaacagc
      901 aacttccgcc gcgcggtgtt ccttggcgta ctgttgcagg taatgcagca attcaccggg
      961 atgaacgtca tcatgtatta cgcgccgaaa atcttcgaac tggcgggtta taccaacact
     1021 accgagcaaa tgtgggggac cgtgattgtc ggcctgacca acgtacttgc cacctttatc
     1081 gcaatcggcc ttgttgaccg ctggggacgt aaaccaacgc taacgctggg cttcctggtg
     1141 atggctgctg gcatgggcgt actcggtaca atgatgcata tcggtattca ctctccgtca
     1201 gcgcagtatt tcgccatcgc catgctgctg atgtttattg tcggttttgc catgagtgcc
     1261 ggtccgctga tttgggtact gtgctccgaa attcagccgc tgaaaggccg cgattttggc
     1321 atcacctgct ccaccgccac caactggatt gccaacatga tcgttggcgc aacgttcctg
     1381 accatgctca acacgctggg taacgccaac accttctggg tgtatgcggc tctgaacgta
     1441 ctgtttatcc tgctgacatt gtggctggta ccggaaacca aacacgtttc gctggaacat
     1501 attgaacgta atctgatgaa aggtcgtaaa ctgcgcgaaa tcggcgctca cgattaatct
     1561 cctcaggctt cctcccatcg cggaggaagc cacctcttgc agtcatcttt tcttcgctct
     1621 atcctctgcc actatgaaaa catcccgtct ccctatcgcc atccagcagg ccgttatgcg
     1681 ccgcctgcgg gaaaaactcg cccaggccaa cctgaagcta gggcgtaact acccggagcc
     1741 aaaactctct tacacccagc gcggaacctc cgccggaaca gcctggctgg aaagctatga
     1801 aatccgcctc aatcccgttt tgctgttgga aaacagtgaa gcttttattg aagaagtggt
     1861 accgcacgaa ctggcacatt tgctggtatg gaaacatttc ggccgcgtag cgccacatgg
     1921 caaagagtgg aagtggatga tggaaagcgt gctgggcgtt cccgcccgtc gtacgcatca
     1981 gttcgaactg caatccgtgc gtcgcaacac cttcccctac cgctgcaagt gccaggagca
     2041 tcagcttacc gtacgccgcc ataatcgcgt agttcgtggc gaggccgtct atcgctgtgt
     2101 tcactgcggt gaacagctgg ttgcgaaata accatctgaa ctatcaggaa ctttcctgat
     2161 ctggctgatt gcataccaaa acaactttcg ctacgttgct ggctcgtttt aacacggagt
     2221 aagtgatgta ccgttatttg tctattgctg cggtggtact gagcgcagca ttttccggcc
     2281 cggcgttggc cgaaggtatc aatagttttt ctcaggcgaa agccgcggcg gtaaaagtcc
     2341 acgctgacgc gcccggtacg ttttattgcg gatgtaaaat taactggcag ggcaaaaaag
     2401 gcgttgttga tctgcaatcg tgcggctatc aggtgcgcaa aaatgaaaac cgagccagcc
     2461 gcgtagagtg ggaacacgtc gttcccgcct ggcagttcgg tcaccagcgc cagtgctggc
     2521 aggacggtgg acgtaaaaac tgcgctaaag atccggtcta tcgcaagatg gaaagcgata
     2581 tgcataacct gcagccgtca gtcggtgagg tgaatggcga tcgcggcaac tttatgtaca
     2641 gccagtggaa tggcggcgaa ggccagtacg gtcaatgcgc catgaaggtc gatttcaaag
     2701 aaaaagctgc cgaaccacca gcgcgtgcac gcggtgccat tgcgcgcacc tacttctata
     2761 tgcgcgacca atacaacctg acactctctc gccagcaaac gcagctgttc aacgcatgga
     2821 acaagatgta tccggttacc gactgggagt gcgagcgcga tgaacgcatc gcgaaggtgc
     2881 aaggcaatca taacccgtat gtgcaacgcg cttgccaggc gcgaaagagc taacctacac
     2941 tagcgggact ctttttgtta acccctaccc cacgcgtaca accgcgtggg gagacgacgc
     3001 ggatttttaa ctatgcgtat cccccgcatt tatcatcctg aaccactgac cagccattct
     3061 cacatcgcgc tttgcgaaga tgccgccaac catatcgggc gcgtactgcg catggggccg
     3121 gggcaggcgt tgcaattgtt tgacggtagc aaccaggtct ttgacgccga aattaccagc
     3181 gccagcaaaa aaagcgtgga agtgaaggtg ctggaaggca agatcgacga tcgcgaatct
     3241 ccgctgcata ttcacctcgg tcaggtgatg tcgcgtggtg aaaaaatgga atttacgatc
     3301 cagaaatcga tcgaactcgg tgtaagcctc attacgccac ttttttctga gcgctgcggc
     3361 gttaaactgg atagtgaacg tctgaacaag aagctccagc agtggcagaa gattgcaatt
     3421 gctgcctgtg agcagtgtgg tcgtaaccgg gtgccggaaa tccgcccagc gatggatctg
     3481 gaagcctggt gtgcagagca ggatgaagga ctgaaactga atcttcaccc gcgcgccagt
     3541 aacagcatca atacgttgcc gttaccggtt gaacgcgtcc gcctgctgat tggcccggaa
     3601 ggcggtttat cggcagatga aattgccatg actgcccgct atcaatttac tgatatcctg
     3661 ttgggacctc gcgttttgcg tacagagaca actgcgctca ccgccattac cgcgctacaa
     3721 gtacgatttg gcgatttggg ctaacggaga agaataatga tcaagctcgg catcgtgatg
     3781 gaccccatcg caaacatcaa catcaagaaa gattccagtt tcgctatgtt gctggaagca
     3841 cagcgtcgtg gttacgaact tcactatatg gagatgggcg atctgtatct gatcaatggc
     3901 gaagcccgcg cccatacccg cacgctgaac gtgaagcaga actacgaaga gtggttttcg
     3961 ttcgtcggtg aacaggatct gccgctggcc gatctcgatg tgattctgat gcgtaaagac
     4021 ccgccgtttg ataccgagtt tatctacgcg acctatattc tggaacgtgc cgaagagaaa
     4081 ggaacgctga tcgttaacaa gccgcagagc ctgcgcgact gtaacgagaa actgtttacc
     4141 gcctggttct ctgacttaac gccagaaacg ctggttacgc gcaataaagc gcagctaaaa
     4201 gcgttctggg agaaacacag cgacatcatt cttaagccgc tggacggtat gggcggcgcg
     4261 tcgattttcc gcgtgaaaga aggcgatcca aacctcggcg tgattgccga aaccctgact
     4321 gagcatggca ctcgctactg catggcgcaa aattacctgc cagccattaa agatggcgac
     4381 aaacgcgtgc tggtggtgga tggcgagccg gtaccgtact gcctggcgcg tattccgcag
     4441 gggggcgaaa cccgtggcaa tctggctgcc ggtggtcgcg gtgaacctcg tccgctgacg
     4501 gaaagtgact ggaaaatcgc ccgtcagatc ggaccgacgt tgaaagaaaa agggctgatt
     4561 tttgttggtc tggatatcat cggcgaccgt ctgactgaaa ttaacgtcac cagcccaacc
     4621 tgtattcgtg agattgaagc agagtttccg gtgtcgatca ccggaatgtt aatggatgcc
     4681 atcgaagcac gtttacagca gcagtaaccc accttagcga gaaggatctc gttgagactc
     4741 tgagtgacag cgcccttctt tccacgcata ctgggcgctg ttgctttttt gaaccaggaa
     4801 acagaacctc tgacaatgaa tttacagcat cactttctta ttgccatgcc tgctctccag
     4861 gatccgattt tccgtcgttc cgtggtctac atttgcgaac ataataccaa tggtgcaatg
     4921 gggatcatcg tcaacaagcc gctggaaaat ctcaaaattg aagggattct ggaaaagctg
     4981 aagatcacgc cggagccgcg tgatgaatca atccgtctgg ataaaccggt tatgctcggc
     5041 ggtccgctgg ctgaagatcg cgggtttatt ttgcatactc cgccctccaa ttttgcttcc
     5101 agcattcgca tttcagacaa cacagtgatg accacttccc gcgatgtgct ggaaacgctc
     5161 ggcaccgata aacaaccgtc tgacgtattg gtggctctgg gttatgcctc ctgggaaaaa
     5221 ggtcaactgg aacaagaaat tctcgataac gcgtggctaa cggccccggc ggatctgaat
     5281 attctgttca aaacgccgat tgccgaccgc tggcgcgagg cggcaaaact gattggtgtg
     5341 gatattctca ccatgcctgg tgtggcaggg cacgcctgat gagtggaacc ttactcgcct
     5401 tcgacttcgg caccaaaagc attggcgtag cggtcggcca acgcattacc ggcaccgctc
     5461 gccctttgcc tgcaattaaa gcacaggacg gtacgccgga ctggaacatt atcgagcgtt
     5521 tactgaaaga gtggcagccg gacgaaatca tcgtcggttt gccgctgaat atggacggca
     5581 ccgagcaacc attgactgcc agagcgcgta aatttgccaa ccgtattcat ggtcgtttcg
     5641 gtgttgaagt aaagctccat gacgaacgtc ttagcaccgt ggaagcccgt tccggtctgt
     5701 ttgaacaggg cggctatcgg gcgctcaaca aaggcaaagt cgactctgcc tctgcggtta
     5761 ttattctcga aagctatttc gagcagggat attaaggcga tctaaaagcc tggcggatag
     5821 tcgttaccgc catcttgccg gatgcggcgt gaacgcctta tccagcacac atctggcagc
     5881 g
//
LOCUS       DAPGUL010000198         5864 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.202, whole genome shotgun sequence.
ACCESSION   DAPGUL010000198 DAPGUL010000000
VERSION     DAPGUL010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5864
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.202"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            39..1190
                     /gene="yiaY"
                     /locus_tag="RHX21_004534"
     CDS             39..1190
                     /gene="yiaY"
                     /locus_tag="RHX21_004534"
                     /EC_number="1.1.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine dehydrogenase"
                     /protein_id="HDV1989614.1"
                     /translation="MASSTFFIPSVNVIGADSLTDAMNMMADYGFTRTLIVTDSMLTK
                     LGMAGDVQKALEERNIFSVIYDGTQPNPTTENVAAGLKLLKENNCDSVISLGGGSPHD
                     CAKGIALVAANGGDIRDYEGVDRSAKPQLPMIAINTTAGTASEMTRFCIITDEARHIK
                     MAIVDKHVTPLLSVNDSSLMIGMPKSLTAATGMDALTHAIEAYVSIAATPITDACALK
                     AVTMIAENLPLAVEDGSNAKAREAMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYNLP
                     HGVCNAVLLPHVQVFNSKVAAARLRDCAAAMGVNVTGKNDAEGAEACINAIRELAKKV
                     DIPAGLRDLNVKEEDFAVLATNALKDACGFTNPIQATHEEIVAIYRAAM"
     gene            1355..2893
                     /gene="aldB"
                     /locus_tag="RHX21_004535"
     CDS             1355..2893
                     /gene="aldB"
                     /locus_tag="RHX21_004535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001551836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase AldB"
                     /protein_id="HDV1989615.1"
                     /translation="MTNNPPSAQIKPGEYGFPLKLKARYDNFIGGEWVAPADGEYYQN
                     LTPVTGQLLCEVASSGKRDIDLALDAAHKVKDKWAHTSVQDRAAILFKIADRMEQNLE
                     LLATAETWDNGKPIRETSAADVPLAIDHFRYFASCIRAQEGGISEVDSETVAYHFHEP
                     LGVVGQIIPWNFPLLMASWKMAPALAAGNCVVLKPARLTPLSVLLLMEIVGDLLPPGV
                     VNVVNGAGGEIGEYLATSKRIAKVAFTGSTEVGQQIMQYATQNIIPVTLELGGKSPNI
                     FFADVMDEEDAFFDKALEGFALFAFNQGEVCTCPSRALVQESIYERFMERAIRRVESI
                     RSGNPLDSVTQMGAQVSHGQLETILNYIDIGKKEGADVLTGGRRKLLEGELKDGYYLE
                     PTILFGQNNMRVFQEEIFGPVLAVTTFKTMEEALELANDTQYGLGAGVWSRNGNLAYK
                     MGRGIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRETHKMMLEHYQQTKCLLVSYSDKP
                     LGLF"
     gene            complement(3112..3255)
                     /locus_tag="RHX21_004536"
     CDS             complement(3112..3255)
                     /locus_tag="RHX21_004536"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989616.1"
                     /translation="MNNSSKTSTVQIKRIKPSIIYRLLLIGLGSPMVIYGLVRPLTIE
                     TRD"
     gene            3438..3761
                     /locus_tag="RHX21_004537"
     CDS             3438..3761
                     /locus_tag="RHX21_004537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3302 domain-containing protein"
                     /protein_id="HDV1989617.1"
                     /translation="MFLDYFALGVLIFVFLVIFYGIIILHDIPYLIAKKRNHPHADAI
                     HVAGWVSLFTLHVIWPFLWIWATLYRPERGWGMQNHDSSVVQLQQRIAGLEKQLADIK
                     SSSAE"
     gene            3767..4903
                     /locus_tag="RHX21_004538"
     CDS             3767..4903
                     /locus_tag="RHX21_004538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HDV1989618.1"
                     /translation="MDLLIILTYVAFAWAMFKIFKIPVNKWTIPTAALGGIFIVSGLI
                     LLMNYNHPYTFKAQKAVISIPVVPQVTGVVIEVTDKKNTLIKKGEVLFRLDPTRYQAR
                     VDRLMADIVTAEHKQRALGAELDEMAANTQQAKATRDKFAKEYQRYARGSQAKVNPFS
                     ERDIDVARQNYLAQEASVKSSAAEQKQIQSQLDSLVLGEHSQIASLKAQLAEAKYNLE
                     QTIVRAPSDGYVTQVLIRPGTYAASLPLRPVMVFIPDQKRQIVAQFRQNSLLRLAPGD
                     DAEVVFNALPGKVFSGKLAAISPAVPGGAYQSTGTLQTLNTAPGSDGVIATIELDEHT
                     DLSALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWVHYLYLDH"
     gene            complement(4900..>5864)
                     /locus_tag="RHX21_004539"
     CDS             complement(4900..>5864)
                     /locus_tag="RHX21_004539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV1989619.1"
                     /translation="QLKYRELKIISVIAASENISHAATVLGIAQANVSKYLADFESKV
                     GLKVFDRTTRQLMLTPFGTALLPYINDMLDRNEQLNNFIADYKHEKRGRVTIYAPTGI
                     ITYLSKHVIDKIKDIGDITLSLKTCNLERNAFYEGVEFPDDCDVLISYAPPKDESLVA
                     SFITQYAVTAYASQRYLEKHPISRPDELEHHSCILIDSMMIDDANIWRFNVAGSKEVR
                     DYRVKGNYVCDNTQSALELARNHLGIVFAPDKSVQSDLQDGTLVPCFQQPYEWWLDLV
                     AIFRKREYQPWRVQYVLDEMLREIRHQLAQSQQLRPEQAAESED"
BASE COUNT         1446 a         1406 c         1536 g         1476 t
ORIGIN      
        1 aagctgccca ccctttttta cactttcagg agtgtgttat ggcatcttca actttcttta
       61 ttccttctgt gaatgtcatc ggcgctgatt cattgactga tgcaatgaat atgatggcag
      121 attatggatt tacccgtacc ttaattgtca ctgacagtat gttaacgaaa ttaggtatgg
      181 cgggcgatgt gcaaaaagca ctggaagaac gcaatatttt tagcgttatt tatgatggca
      241 cccaacctaa ccccaccacg gaaaacgtcg ccgcaggttt gaaattactt aaagagaata
      301 attgcgatag cgtgatctcc ttaggcggtg gttctccaca cgactgcgca aaaggtattg
      361 cgctggtggc agccaatggc ggcgatattc gcgattacga aggcgttgac cgctctgcaa
      421 aaccgcagct gccgatgatc gccatcaata ccacggcggg tacggcctct gaaatgaccc
      481 gtttctgcat catcactgac gaagcgcgtc atatcaaaat ggcgattgtt gataaacatg
      541 tcactccgct gctttctgtc aatgactcct ctctgatgat tggtatgccg aagtcactga
      601 ccgccgcaac gggtatggat gccttaacgc acgctatcga agcgtatgtt tctattgccg
      661 ccacgccgat cactgacgct tgtgcactga aagccgtgac catgattgcc gaaaatctgc
      721 cgttagccgt tgaagatggc agtaatgcga aagcgcgtga agcaatggct tatgcccagt
      781 tcctcgccgg tatggcgttc aataatgctt ctctgggtta tgttcatgcg atggcgcacc
      841 agctgggcgg tttctacaac ctgccacacg gtgtatgtaa cgccgttttg ctgccgcatg
      901 ttcaggtatt caacagcaaa gtcgccgccg cacgtctgcg tgactgtgcc gctgcaatgg
      961 gcgtgaacgt gacaggtaaa aacgatgcgg aaggtgctga agcctgcatt aacgccatcc
     1021 gtgaactggc gaagaaagtg gatatcccgg caggcctacg cgacctgaac gtgaaagaag
     1081 aagatttcgc ggttctggcg actaatgccc tgaaagatgc ctgtggtttt actaacccga
     1141 tccaggcaac tcacgaagaa attgtggcga tttatcgcgc agcgatgtaa tcatcatttc
     1201 cacaacggct ggcaaattgt cagccgcttt ttcaactatc tctgtaaccc ttgcccgtaa
     1261 attcgtgata gctgtcgtaa agctgttacc gactggcgaa gatttcgcca gtcacgtcta
     1321 cccttgttat acctcacacc gcaaggagac gatcatgacc aataatcccc cttcagcaca
     1381 gattaagccc ggcgagtatg gtttccccct caagttaaaa gcccgctatg acaactttat
     1441 tggcggcgaa tgggtagccc ctgccgacgg cgagtattac cagaatctga cgccggtgac
     1501 cgggcagctg ctgtgcgaag tggcgtcttc gggcaaacga gacatcgatc tggcgctgga
     1561 tgctgcgcac aaagtgaaag ataaatgggc gcacacctcg gtgcaggatc gcgcggcgat
     1621 tctgtttaag attgccgatc gaatggaaca aaaccttgag ctgttagcga cggctgaaac
     1681 ctgggataac ggcaaaccca ttcgcgaaac cagtgctgcc gacgtgccgc tggcgattga
     1741 ccattttcgc tatttcgcct cgtgtattcg ggcgcaggaa ggtgggatca gtgaagttga
     1801 tagcgaaacc gtggcctatc atttccatga accgttaggc gtggtggggc agattatccc
     1861 gtggaacttc ccgctgctga tggcgagctg gaaaatggct cccgcgctgg cggcgggcaa
     1921 ctgtgtggtg ctgaaacccg cacgtcttac cccgctttct gtactgctgc taatggaaat
     1981 cgtcggtgat ttactgccgc cgggcgtggt gaacgtggtc aacggcgcag gtggggaaat
     2041 tggcgaatat ctggcgacct cgaaacgcat cgccaaagtg gcgtttaccg gctcaacgga
     2101 agtgggccaa caaattatgc aatacgccac gcaaaacatt attccggtga cgctggagct
     2161 gggcggcaaa tcgccaaata tcttctttgc tgatgtgatg gatgaagaag atgccttttt
     2221 cgataaagcg ctggaaggct ttgcactgtt tgcctttaac cagggtgaag tttgcacctg
     2281 tccgagtcgt gccttagtgc aggagtcaat ctacgaacgc tttatggaac gcgccatccg
     2341 ccgtgtcgaa agcattcgca gcggtaaccc actcgacagc gtgacgcaaa tgggcgcgca
     2401 ggtttctcac gggcaactgg aaaccatcct caactacatt gatatcggta aaaaagaggg
     2461 cgctgacgtg ctcacaggcg ggcggcgcaa gctgctggaa ggtgaactga aagacggcta
     2521 ctacctcgaa ccgacgattc tgtttggtca gaacaatatg cgggtgttcc aggaggagat
     2581 ttttggcccg gtgctggcgg tgaccacctt caaaacgatg gaagaagcgc tggagctggc
     2641 gaacgatacg caatatggcc tgggcgcggg cgtctggagc cgcaacggta atctggccta
     2701 taagatgggg cgcggcatac aggctgggcg cgtgtggacc aactgttatc acgcttaccc
     2761 ggcacatgcg gcgtttggtg gctacaaaca atcaggtatc ggtcgcgaaa cccacaagat
     2821 gatgctggag cattaccagc aaaccaagtg cctgctggtg agctactcgg ataaaccgtt
     2881 ggggctgttc tgatataaga agctggtcgc attgggtatt cattgcctga tgcgacgctt
     2941 acgcgtctta tcatgcctac gggaacctga ccgtaggccg gataaggcgt acacgccgca
     3001 tccggcataa acaaagcgca cgttgttaca atttacgttt taaacctacg tgcgcaataa
     3061 cccagactac gccaacagaa gtgcgtttct ggggcgtgtt ttgtcaggag tttaatctcg
     3121 cgtttcgatg gtgagcgggc gaaccaggcc gtaaatcacc attggtgatc cgaggccaat
     3181 cagcaataaa cggtagataa ttgaaggttt aatacgctta atctgtactg tggatgtttt
     3241 actggagtta ttcattagtt tggccaatag ttccactatt tcaatatgat aaacctcgtc
     3301 ctgttgaaaa accagacagc acatttaaga aagtatataa aaaacaatat gtcgttatat
     3361 aaataaggaa attgcactgc atcatggcat ttcataatat gcgttaattg ttctttttta
     3421 tattctttga gggaaatatg ttcctggact attttgcact gggagtgctt atttttgtat
     3481 ttctggtgat attctatggg attattattt tacatgatat tccctacctg attgctaaaa
     3541 aacgtaatca tcctcatgcc gacgccattc atgttgctgg ttgggtgagt ctttttacgt
     3601 tacatgttat ctggccattt ttgtggattt gggccacgct ttaccgcccg gagcggggat
     3661 ggggaatgca aaaccatgac tcctccgttg tgcaactaca acagcgtatt gccgggctgg
     3721 agaaacagct cgccgacatc aaatcctctt ctgccgagta atacttatgg atttactgat
     3781 tattttaacc tatgtggctt tcgcatgggc aatgtttaag atcttcaaaa ttcctgtaaa
     3841 taaatggacc attcccaccg cggccctggg tggcatattt attgtcagcg gtttaattct
     3901 gttaatgaac tataaccatc cgtatacctt taaagcgcaa aaagcggtta tttctattcc
     3961 agttgtcccg caggtgacag gcgtggtgat cgaagtgacg gacaagaaaa atacgctgat
     4021 taaaaaaggc gaggtgcttt ttcgactgga cccgacgcgt tatcaggcgc gggtggatcg
     4081 gctgatggcg gatatcgtta ccgcagaaca taaacagcgg gcgttgggcg cagagttaga
     4141 tgagatggcg gcgaatactc agcaggcaaa ggccacgcgg gataaattcg ctaaagagta
     4201 tcagcgttac gcacgcggca gccaggcgaa agtaaacccg ttttcagaac gcgatatcga
     4261 tgtggcgcgg caaaattatc tggcgcagga agcctccgtg aagtcatcgg cggcggaaca
     4321 aaaacagatc cagagccagc tggatagcct ggtgttgggt gaacattctc aaatcgccag
     4381 cctgaaagca cagctcgcgg aagcaaaata taaccttgag cagacgatag tgcgtgcgcc
     4441 gagcgatggt tatgtgaccc aggtactgat tcgtccgggt acctatgccg cgtcgctgcc
     4501 gctacgtccg gtgatggtgt ttatacccga tcagaaacga caaatcgtgg cgcagttccg
     4561 tcagaactcc ttgctgcgac tggctcctgg cgacgatgcg gaagtggtgt ttaatgctct
     4621 gccaggtaag gtattcagcg gtaagctggc agccattagt ccagccgttc ccggcggagc
     4681 ttatcagtcg accggcacct tacagacgtt aaacacagcg ccgggttcag atggcgttat
     4741 cgcgaccatt gaactggatg agcacactga tttgagcgct ttaccagacg gtatttacgc
     4801 ccaggtggcg gtttactctg atcatttcag ccatgtctcg gtgatgcgca aagtgctatt
     4861 acgcatgacc agctgggtgc attaccttta tctcgatcat taatcttcgc tttccgccgc
     4921 ttgttcaggc cgcagttgct gcgactgagc aagctggtgg cgaatttcac gcagcatttc
     4981 atccagcaca tactggaccc gccagggctg gtattcccgt ttacggaaga tagccaccag
     5041 atccagccac cattcatagg gttgctgaaa gcagggcacc agcgtgccgt cttgcaggtc
     5101 gctctgcaca cttttgtctg gcgcaaacac aatccccagg tgatttcgtg ccagctccag
     5161 cgcagattgc gtgttgtcgc aaacgtaatt tcccttcacg cgataatctc gcacctcttt
     5221 actcccggcg acgttgaagc gccagatatt cgcgtcatca atcatcatcg agtcgatcaa
     5281 aatacaggag tgatgttcga gttcgtcagg acggctaatg ggatgtttct caagatagcg
     5341 ctggctggca taagcggtta cggcatattg ggtaataaaa ctggcaacca gcgattcatc
     5401 ttttggtgga gcgtagctga ttaaaacatc acaatcatca ggaaattcga cgccttcata
     5461 aaaggcatta cgctcaagat tgcaggtttt tagcgataag gtgatatcac cgatatcttt
     5521 aattttatcg attacatgtt tggataaata ggtaattatg ccggttgggg cgtagatggt
     5581 gacccgacca cgtttctcat gcttataatc tgcaataaaa ttattaagct gctcgtttct
     5641 gtccagcatg tcgttgatgt acggtaacag cgcggtacca aaaggtgtga gcatcagctg
     5701 ccgggtggtt cggtcaaaga cttttaaacc cacttttgat tcaaaatcag caagatattt
     5761 gctgacgttg gcctgtgcga tgccaagtac agtcgcggca tggctgatat tttcactggc
     5821 agcgattacc gagataattt ttaactcccg gtacttaagt tgta
//
LOCUS       DAPGUL010000199         5858 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.203, whole genome shotgun sequence.
ACCESSION   DAPGUL010000199 DAPGUL010000000
VERSION     DAPGUL010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5858)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5858)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5858
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.203"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(360..1319)
                     /gene="nrdF"
                     /locus_tag="RHX21_004540"
     CDS             complement(360..1319)
                     /gene="nrdF"
                     /locus_tag="RHX21_004540"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HDV1989620.1"
                     /translation="MKLSRISAINWNKISDDKDLEVWNRLTSNFWLPEKVPLSNDIPA
                     WQTLTVVEQQLTMRVFTGLTLLDTLQNVIGAPSLMPDALTPHEEAVLSNISFMEAVHA
                     RSYSSIFSTLCQTKDVDAAYAWSEENAPLQRKAQIIQQHYRGDDPLKKKIASVFLESF
                     LFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGYYIGYKYQKNMEKISLGQREEL
                     KSFAFDLLLELYDNELQYTDELYAETPWADDVKAFLCYNANKALMNLGYEPLFPAEMA
                     EVNPAILAALSPNADENHDFFSGSGSSYVMGKAVETEDEDWNF"
     gene            complement(1380..3473)
                     /gene="nrdE"
                     /locus_tag="RHX21_004541"
     CDS             complement(1380..3473)
                     /gene="nrdE"
                     /locus_tag="RHX21_004541"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HDV1989621.1"
                     /translation="MATTTAECLTQETMDYHALNAMLNLYDSAGRIQFDKDRQAVDAF
                     MATHVRPNSVTFSSQQQRLNWLVNEGYYDESVLNRYSRDFVITLFAHAHTSGFRFQTF
                     LGAWKFYTSYTLKTFDGKRYLEDFADRVTMVALTLAQGDETLALQLTDEMLSGRFQPA
                     TPTFLNCGKQQRGELVSCFLLRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAG
                     APIKRIENQSSGVIPVMKMLEDAFSYANQLGARQGAGAVYLHAHHPDILRFLDTKREN
                     ADEKIRIKTLSLGVVIPDITFHLAKENAQMALFSPYDVERVYGKPFADVAISQHYDEL
                     VADERIRKKYLNARDFFQRLAEIQFESGYPYIMYEDTVNRANPIAGRINMSNLCSEIL
                     QVNSASEYDENLDYARTGHDISCNLGSLNIAHTMDSPNFARTVETAVRGLTAVSDMSH
                     IRSVPSIEAGNAASHAIGLGQMNLHGYLAREGIAYGSPEALDFTNLYFYTITWHALRT
                     SMLLARERGETFAGFKQSRYASGEYFSQYLQGNWQPKTAKVGELFARSGITLPTREMW
                     AQLRDDVMRYGIYNQNLQAVPPTGSISYINHATSSIHPIVAKVEIRKEGKTGRVYYPA
                     PFMTNENLALYQDAYEIGAEKIIDTYAEATRHVDQGLSLTLFFPDTATTRDINKAQIY
                     AWRKGIKTLYYIRLR"
     gene            complement(3446..3856)
                     /gene="nrdI"
                     /locus_tag="RHX21_004542"
     CDS             complement(3446..3856)
                     /gene="nrdI"
                     /locus_tag="RHX21_004542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HDV1989622.1"
                     /translation="MSQLVYFSSSSENTQRFIERLGLPAVRIPLNERERIQVDEPYIL
                     IVPSYGGGGTAGAVPRQVIRFLNDEHNRALLRGVIASGNRNFGEAYGRAGDVIAQKCG
                     VPWLYRFELMGTQSDIENVRKGVTEFWQRQPQNA"
     gene            complement(3853..4098)
                     /gene="nrdH"
                     /locus_tag="RHX21_004543"
     CDS             complement(3853..4098)
                     /gene="nrdH"
                     /locus_tag="RHX21_004543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HDV1989623.1"
                     /translation="MRITIYTRNDCVQCHATKRAMENRSFDFEMINVDRVPEAAEALR
                     AQGFRQLPVVIAGDLSWSGFRPDMINRLHPAPHAASA"
     gene            complement(4346..4675)
                     /locus_tag="RHX21_004544"
     CDS             complement(4346..4675)
                     /locus_tag="RHX21_004544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311560.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF883 domain-containing protein"
                     /protein_id="HDV1989624.1"
                     /translation="MFNRPNRNDVDDGVQDIQNDVNQLADSLESVLKSWGSDAKGEAE
                     AARSKAQALLKETRARMHGRTRVQQAARDAVGCADSFVRERPWCSVGTAAAVGIFIGA
                     LLSMRKS"
     gene            4827..5171
                     /locus_tag="RHX21_004545"
     CDS             4827..5171
                     /locus_tag="RHX21_004545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgaC family protein"
                     /protein_id="HDV1989625.1"
                     /translation="MYLRPDEVARVLEKVGFTVDVVTQKAYGYRRGENYVYVNREARM
                     GRTALVIHPTLKERSSTLAEPASDIKTCDHYQQFPLYLAGERHEHYGIPHGFSSRVAL
                     ERYLNGLFGEAS"
     gene            complement(5208..5657)
                     /gene="alaE"
                     /locus_tag="RHX21_004546"
     CDS             complement(5208..5657)
                     /gene="alaE"
                     /locus_tag="RHX21_004546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-alanine exporter AlaE"
                     /protein_id="HDV1989626.1"
                     /translation="MFSPQSRLRHAVADTFAMVVYCSVVNMCIEVFLSGMSFEQSFYS
                     RLVAIPVNILIAWPYGMYRDLFMRAARKVSPSGWIKNLADILAYVTFQSPVYVAILLV
                     VGADWHQIMAAVSSNIVVSMLMGAVYGYFLDYCRRLFKVSRYQQVKA"
BASE COUNT         1510 a         1433 c         1438 g         1477 t
ORIGIN      
        1 gccatgcaat agaaagattc ctttatttgt ttatgtcgat atattaccca atggaaatag
       61 tcactttttt ctaccctaac atactgagaa tctgaggcaa cccctgaggg caaatgtggc
      121 atgaatattg atgcgagcaa atcgccggaa tttcccgtga tataagggct gagagcaaat
      181 cgagaaaagt tgatattttt tgtcatagat agcgaaaaaa cgcctgaata ttgtagtttc
      241 aggcgaataa tgcaacagag tatcagtgta gatcactaca gaatatttgc gtgataaaaa
      301 gctatttggc gggaattatt tccctgctgc gggtagtgat atttttgaaa ataacaccct
      361 cagaaattcc agtcttcatc ttctgtttca accgctttcc ccatcacata agaggagcct
      421 gaaccggaaa agaaatcgtg attttcatcg gcattcggcg aaagcgcggc gaggattgcc
      481 ggattcactt ccgccatttc tgcgggaaat aacggttcgt agcccagatt catcaaagcc
      541 ttattggcgt tgtaacagag aaacgctttc acatcgtcag cccacggggt ttcggcgtac
      601 agctcatcgg tgtattgcaa ctcgttgtcg tagagttcca gcaacaaatc gaaggcgaaa
      661 ctcttcaact cttcacgttg tcccagagat atcttttcca tgtttttctg atatttatag
      721 cctatgtagt aaccgtggac tgcttcatcg cggataatca gacggatcag atctgcggta
      781 ttggtcagct ttccgcggct ggaaaaatac atcggcagcc agaaaccgga ataaaacaaa
      841 aaagattcaa gaaacacact ggcgattttc tttttcagcg gatcatcacc gcgataatgt
      901 tgctgaataa tctgagcttt tcgctgcaac ggtgcgtttt cttcactcca ggcgtaggcg
      961 gcatcgacat ctttggtctg acacagcgtc gagaaaatcg aactgtaaga gcgggcatga
     1021 accgcttcca taaagctgat attcgataat accgcttctt catgaggcgt gagtgcatcg
     1081 ggcatcagcg aaggcgcgcc gataacattt tgcagcgtgt cgagcagcgt caggccagta
     1141 aaaacgcgca tcgtcagttg ttgttctacg acagttaatg tctgccaggc aggaatatcg
     1201 ttcgacagcg gcaccttttc tggtagccag aaattgctgg tcaggcgatt ccacacctcc
     1261 agatctttat cgtcagatat cttgttccag ttgatggcgc tgatacgtga gagtttcata
     1321 gatattcctt aaagtgcaca ggagacgcag ccttcaattt cagtgccttc cagcgccatc
     1381 taacgcaggc gaatgtaata gagcgttttg atacctttgc gccaggcgta aatctgcgct
     1441 ttgttgatat cgcgagtggt ggcggtatcg gggaaaaaca gcgtcagcga caaaccctga
     1501 tcgacatggc gagtcgcttc cgcgtaggtg tcgatgatct tttctgcgcc gatttcgtaa
     1561 gcatcctgat acagcgccag attctcgtta gtcataaacg gggcagggta gtaaacgcgt
     1621 cctgttttgc cctctttgcg tatctctact ttcgccacaa tcggatgaat actcgacgta
     1681 gcatggttga tataagagat agaaccggtt ggcggcaccg cctgaagatt ctggttataa
     1741 atgccgtagc gcatcacgtc gtcgcgcagt tgcgcccaca tctcacgggt aggtaacgta
     1801 ataccgctac gggcaaacag ttcgccaact ttcgccgttt tcggctgcca gttcccttgc
     1861 agatattggc tgaaatattc accactggca tagcgtgact gtttgaaccc ggcgaaggtt
     1921 tcaccgcgtt cgcgtgccag caacatcgag gtacgcagtg cgtgccaggt gatggtatag
     1981 aaatagagat tggtgaaatc cagtgcttcc ggcgaaccat aagcgatgcc ttctcgcgcc
     2041 agataaccgt gtaaattcat ctgccccagc ccgatggcgt gtgaggcggc atttccggct
     2101 tcgatggacg gcacgctgcg gatatgactc atatctgaca ccgccgttaa accgcgtacg
     2161 gcagtctcta ccgtgcgggc aaagttgggg gaatccatgg tgtgggcaat attcaacgaa
     2221 cctaaattgc aggaaatatc atggcctgta cgggcatagt cgagattctc gtcatactct
     2281 gaggcgctgt taacctgcaa aatttctgag cagagattac tcatatttat gcgcccggcg
     2341 atagggttag cacggtttac cgtgtcttca tacatgatgt agggatagcc ggactcaaac
     2401 tggatttctg ccagtcgctg gaagaaatca cgggcgttga ggtatttttt gcgaatgcgt
     2461 tcatcggcaa ccagttcgtc atagtgttgg ctgatggcca catcggcaaa cggcttgcca
     2521 taaactcgct ctacgtcata aggcgaaaac agcgccatct gcgcattctc ttttgccaga
     2581 tggaaagtga tatccgggat caccacgccc agcgacagtg ttttaatgcg gattttctcg
     2641 tcggcatttt cccgtttcgt atcgagaaaa cgcagaatat cgggatgatg ggcatgtaaa
     2701 tagactgcac cagccccctg acgagcgccg agctggttgg cataggaaaa tgcgtcttcc
     2761 agcattttca tcaccggaat cacgccagaa gattgatttt caatacgttt aattggcgcg
     2821 cccgcttccc gcagattcga cagcaaaaat gccacgccgc cgccgcgttt cgacagttgc
     2881 agtgcggaat ttaccgcccg gccaatcgac tccatattgt cttcaatacg cagcaaaaaa
     2941 caggaaacca gttcgccgcg ctgctgctta ccacagttga ggaatgtcgg tgttgcaggc
     3001 tgaaagcgtc ctgacagcat ctcatcggtc agttgcaacg ccagtgtttc atcgccttgt
     3061 gccagcgtta gcgccaccat cgtgactcga tcggcaaaat cttccagata acgcttaccg
     3121 tcgaatgtct tcaacgtata gctggtgtaa aacttccatg ccccgaggaa tgtctggaaa
     3181 cgaaaaccgc tggtgtgtgc gtgggcaaac agcgtaatga caaagtcgcg agagtagcga
     3241 ttaagaacgc tttcatcata gtaaccttcg ttgaccagcc agttcaggcg ctgctgctgg
     3301 ctactgaagg tcacactgtt cggacgcaca tgcgtcgcca taaaggcgtc aacggcctgg
     3361 cggtctttat cgaactgaat gcgacctgcg ctatcgtaga ggttaagcat cgcattcagc
     3421 gcgtggtaat ccatcgtttc ctgcgtcagg cattctgcgg ttgtcgttgc caaaattcgg
     3481 ttactccttt acgaacgttt tcgatatcgc tttgcgtacc catgagttca aaacggtaca
     3541 gccacggcac gccgcatttc tgagcaatca catctccggc acggccatac gcctcaccaa
     3601 agttgcgatt acccgaagca ataacgccgc gaagcaacgc ccggttgtgc tcgtcgttta
     3661 aaaagcgaat tacctgtcgt ggcaccgcgc cagccgtacc gccgccgccg taagagggca
     3721 cgatcaggat gtaaggctcg tctacctgaa tccgttcccg ctcattgagc gggatgcgca
     3781 ccgcgggcag acctaaacgt tcgataaaac gctgcgtatt ttcggagctg ctggagaagt
     3841 agacgagctg gctcatgcac tggccgcgtg tggcgctgga tgcagacggt taatcatgtc
     3901 cggacggaaa ccagaccagc taagatcgcc agcaatcact accggcaact gacgaaagcc
     3961 ctgagcacgc aacgcttctg ccgcttcagg aacgcgatcg acattaatca tttcaaaatc
     4021 aaagctccgg ttttccatcg cccgtttggt ggcgtggcac tgaacgcaat cgttacgagt
     4081 gtaaatagta atgcgcatga ttcgtatttc cgtttaaaat gaagatacgg cgcgatgata
     4141 cgcgtcgggt tgtctcactg ttgatacaga gatactagat gtagttgaaa aaagattcaa
     4201 ccacacaata tatagcaaat agtggtcgaa attaccctgg atatgagcgt gacggggtag
     4261 gggaattttt gtgattcacc aggcaaaaag aaaccccgaa gacaggcttc ggggtcaaag
     4321 acgcgtattt attatcattt ttgcactacg atttgcgcat gcttaatagt gcgccgataa
     4381 aaatacctac cgcagctgct gtacccacgc tacaccaggg tctttcacga acaaaagaat
     4441 ccgcgcagcc aacggcatcg cgtgcggctt gctggacgcg agtacgacca tgcattcgcg
     4501 ccctggtttc tttcagcaat gcctgagctt tactgcgtgc ggcttcagct tcccctttgg
     4561 cgtcgctgcc ccaagacttt aatacagatt cgaggctgtc agctaattga ttgacatcat
     4621 tctggatatc ctgcacgcca tcatcaacgt cgttgcggtt cggtcggtta aacatatgat
     4681 cccccattag aattcgatgt aattttcagt gtagaccata attttcttaa ctgaggttca
     4741 tcgcggcttt atggactttt ctgaaagcgt tgtgaatgcg caatcaggta aggtaggccc
     4801 gcggttgata ataacgagga tcaaatatgt atttacgacc agacgaggtg gcgcgcgtac
     4861 ttgaaaaagt cggttttact gtcgatgtgg taacccagaa agcgtatggt taccgccgtg
     4921 gggaaaatta tgtctatgtt aatcgcgaag cgcgaatggg acgtaccgct ctggtaattc
     4981 atccaacatt aaaagaacgc agttcaacac tggctgaacc cgcttccgat attaaaactt
     5041 gcgatcatta ccagcaattt ccgctctatt tagcaggcga gcgacacgag cattacggta
     5101 tcccgcatgg cttcagttcg cgtgttgcgc ttgaacgtta tttgaatggt ttatttggcg
     5161 aagccagtta aagacgcgac tggcgatgcc agtcgcgaaa agaagagtca ggcttttacc
     5221 tgctggtaac ggctgacttt aaacagtcgg cggcaataat cgaggaagta gccataaacc
     5281 gcccccatca acatcgaaac aacgatgttt gaactgaccg ccgccataat ctgatgccag
     5341 tctgcgccca ccactaacaa gatcgccaca tacaccggtg actggaacgt cacataagcc
     5401 aggatatcag ccagattttt tatccagccc gacgggctaa ctttgcgtgc cgcgcgcata
     5461 aacagatcgc ggtacatacc gtatggccat gcaattaaga tgttcaccgg aatcgctacc
     5521 aatctggaat aaaaagactg ttcgaagctc attccggaga ggaaaacttc aatacacatg
     5581 ttcacgacag aacagtaaac aaccatcgcg aacgtatctg caactgcatg acgcaagcgt
     5641 gactgcggtg agaacatgct aatgctcctt aataaaagcg taatgggatg ttaatggaga
     5701 tgaaagcagt ggatctcatt gccatctgca ttttcgcata gcgtatatcg ctggctatga
     5761 ctattcaatt agtgaaaaat ttttatttag tcagtttttg tagataaaat attccgtaac
     5821 ggctcgtttt ttgtacattg tggattttta catgccga
//
LOCUS       DAPGUL010000200         5850 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.204, whole genome shotgun sequence.
ACCESSION   DAPGUL010000200 DAPGUL010000000
VERSION     DAPGUL010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5850
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.204"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(89..616)
                     /gene="mobB"
                     /locus_tag="RHX21_004547"
     CDS             complement(89..616)
                     /gene="mobB"
                     /locus_tag="RHX21_004547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418293.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HDV1989627.1"
                     /translation="MAGKTMIPLLAFAAWSGTGKTTLLKKLIPALCARGIRPGLIKHT
                     HHDMDVDKPGKDSYELRKAGAAQTIVASQQRWALMTETPDEEELDLQFLASRMDTSKL
                     DLILVEGFKHEEIAKIVLFRDGAGHRPEELVIDRHVIAVASDVPLNLDVALLDINDVE
                     GLADFVVEWMQKQNG"
     gene            complement(598..1182)
                     /gene="mobA"
                     /locus_tag="RHX21_004548"
     CDS             complement(598..1182)
                     /gene="mobA"
                     /locus_tag="RHX21_004548"
                     /EC_number="2.7.7.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase MobA"
                     /protein_id="HDV1989628.1"
                     /translation="MNLMTTITGVVLAGGKARRMGGVDKGLLELNGKPLWQHVADALM
                     TQLSHVVVNANRHQEIYQASGLKVIEDSLADYPGPLAGMLSVMQQEAGEWFLFCPCDT
                     PYIPPDLAARLNHQRKDAPVVWVHDGERDHPTIALVNRAIEPLLLEYLQAGERRVMVF
                     MRLAGGHAVDFSDHKDAFVNVNTPEELARWQEKR"
     gene            1252..1521
                     /locus_tag="RHX21_004549"
     CDS             1252..1521
                     /locus_tag="RHX21_004549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihD family protein"
                     /protein_id="HDV1989629.1"
                     /translation="MKCKRLNEVIELLQPAWQKEPDLNLLQFLQKLAKESGFDGELAD
                     LTDDILIYHLKMRDSAKDAVIPGLQKDYEEDFKTALLRARGVIKE"
     gene            1598..2584
                     /gene="srkA"
                     /locus_tag="RHX21_004550"
     CDS             1598..2584
                     /gene="srkA"
                     /locus_tag="RHX21_004550"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response kinase SrkA"
                     /protein_id="HDV1989630.1"
                     /translation="MNNSAFTFQTLHPDTIMDALFEHGIRVDSGLTPLNSYENRVYQF
                     QDEDRRRFVVKFYRPERWTADQILEEHQFALQLVNDEVPVAAPVAFNGQTLLNHQGFY
                     FAVFPSVGGRQFEADNIDQMEAVGRYLGRMHQTGRKQLFIHRPTIGLNEYLIEPRKLF
                     EDATLIPSGLKAAFLKATDELIAAVTAHWREDFTVLRLHGDCHAGNILWRDGPMFVDL
                     DDARNGPAVQDLWMLLNGDKAEQRMQLETIIEAYEEFSEFDTAEIGLIEPLRAMRLVY
                     YLAWLMRRWADPAFPKNFPWLTGEDYWLRQTATFIEQAKVLQEPPLQLTPMY"
     gene            2601..3227
                     /gene="dsbA"
                     /locus_tag="RHX21_004551"
     CDS             2601..3227
                     /gene="dsbA"
                     /locus_tag="RHX21_004551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbA"
                     /protein_id="HDV1989631.1"
                     /translation="MKKIWLALAGLVLAFSASAAQYEDGKQYTTLEKPVAGAPQVLEF
                     FSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALG
                     VEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKA
                     AADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTVKYLSEKK"
     gene            3382..4812
                     /locus_tag="RHX21_004552"
     CDS             3382..4812
                     /locus_tag="RHX21_004552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418298.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdgA family protein"
                     /protein_id="HDV1989632.1"
                     /translation="MIRKSATGVIVALAVIWGGGTWYTGTQIQPGVEKFIKDFNDAKK
                     KGEHAYDMTLSYQNFDKGFFNSRFQMQMTFDNGAPDLNIKPGQKVVFDVDVEHGPLPI
                     TMLMHGNVIPALAAAKVNLVNNELTQPLFIAAKNKSPVEATLRFAFGGSFSTTLDVAP
                     AEYGKFSFGEGQFTFNGDGSSLSNLDIEGKVEDIVLQLSPMNKVTAKSFTIDSLARLE
                     EKKFPVGESESKFNQINIINHGEDVAQIDAFVAKTRLDRVKDKDYINVNLTYELDKLT
                     KGNQQLGSGEWSLIAESIDPSAVRQFIIQYNIAMQKQLAAHPELANDEVALQEVNAAL
                     FKEYLPLLQKSEPTIKQPVRWKNALGELNANLDISIADPAKSSSSTNKDIKSLNFDVK
                     LPLNVVTETAKQLNLSEGMDAEKAQKQADKQISGMMTLGQMFQLITIDNNTASLQLRY
                     TPGKVVFNGQEMSEEEFMSRAGRFVH"
     gene            complement(4853..5785)
                     /locus_tag="RHX21_004553"
     CDS             complement(4853..5785)
                     /locus_tag="RHX21_004553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HDV1989633.1"
                     /translation="MANLLNKFIMTRILAAITLLLSIVLTILVTIFCSVPIIIAGIVK
                     LLLPVPVIWRKVSRFCDFMMYCWCEGLAVLLHLNPHLQWEVHGLEGLSKKNWYLLICN
                     HRSWADIVVLCVLFRKHIPMNKYFLKQQLAWVPFLGLACWSLDMPFMKRYSRAYLLRH
                     PERRGKDVETTRRSCEKFRLHPTTIVNFVEGSRFTQEKHQQTHSTFQNLLPPKAAGIA
                     MALNVLGKQFDKLLNVTLCYPDNNRQPFFDMLSGKLTRIVVHVDLQPIADELHGDYIN
                     DKSFKRHFQQWLNSLWQEKDRLLTSLMSSQRQNK"
BASE COUNT         1631 a         1319 c         1364 g         1536 t
ORIGIN      
        1 aggccatcct gacggatggc ctttttgcat tggcgcagaa aaaaatgccg gatgcgacgc
       61 tggcgcgtct tatccagcct actcttgctt atccgttctg cttttgcatc cactccacca
      121 caaaatcagc cagcccctca acatcattaa tatccagtaa tgcgacatca agattaagcg
      181 gcacatcact ggctacagca ataacatgcc tgtctatcac taattcttca ggtcgatgtc
      241 cggctccatc gcgaaacagc acaatctttg cgatctcttc atgcttaaac ccttcgacca
      301 gaatcaaatc cagctttgag gtatccattc gacttgcgag aaactgtaga tccagctctt
      361 cttcgtctgg tgtttccgtc atcaaggccc atcgttgctg gctggcaacg atggtttgtg
      421 ccgcgccagc cttgcgcagc tcatagctat ctttgcctgg cttatcaaca tccatatcat
      481 ggtgcgtatg cttaatcagc cctggacgga tccctctggc gcataatgcc gggatcagtt
      541 ttttcaaaag cgtagttttt ccggtaccac tccacgcggc aaaggcgagt aacggtatca
      601 tcgtttttcc tgccatcggg caagctcctc tggcgtattc acgttaacaa atgcatcttt
      661 atgatcgctg aaatcaaccg catgaccgcc agccagacgc ataaatacca ttacccggcg
      721 ttctcctgct tgcagatatt ccagtaataa aggctcaata gcgcggttta ccagagcaat
      781 agtcgggtga tcgcgttcac cgtcatggac ccacacgaca ggcgcatctt tgcgctgatg
      841 attaagcctg gctgctaaat cagggggaat gtaaggcgta tcgcacgggc aaaacaaaaa
      901 ccactcacca gcttcctgct gcattactga aagcattcct gccagagggc ctgggtaatc
      961 cgccagtgaa tcttcaatca ctttcagacc gcttgcctga tagatttcct gatgacgatt
     1021 agcattaacc acgacgtgag agagctgcgt cataagcgcg tcagcgacat gttgccataa
     1081 tggtttgccg tttaattcaa gcaatccttt atctacgccg cccattcgtc tggctttacc
     1141 gcctgccagc acaacgcctg ttatcgtcgt catcagattc accgatatcg cctcttttat
     1201 tgtgggattg accctgctaa cgtgtctgtc tcaagagtaa ggagcatcac tatgaaatgt
     1261 aaacgtctga atgaagttat tgaactcctc cagccagcct ggcaaaaaga gccagacctt
     1321 aacctgctgc aatttttgca gaaactggcg aaagagtcag gttttgacgg cgaactggcg
     1381 gatttgacgg atgacattct gatctatcac ctgaaaatgc gtgattccgc gaaagatgcg
     1441 gtgatcccgg gtttgcagaa agattatgaa gaagacttca aaacggcgct gttacgcgct
     1501 cgcggcgtaa ttaaagagta aaagcttgta agcggcgcca ccaaaatcat cgtgaaatga
     1561 tatccttcgt cattcgtaat gttttccgga tgatgggatg aataacagcg cttttacttt
     1621 ccagacacta cacccggata ccatcatgga cgctctgttt gagcatggga tccgggtgga
     1681 ttccggtctt accccgctta acagctatga aaaccgtgtc tatcaatttc aggacgaaga
     1741 tcgtcgacgt tttgtcgtca aattttatcg ccctgaacgt tggacagccg atcaaatcct
     1801 cgaagaacat caatttgcgt tgcagctggt aaatgatgaa gttccggtcg cagcacctgt
     1861 ggcctttaac ggtcagactt tattgaatca tcagggattt tatttcgctg tttttccaag
     1921 cgtcggtggt cgccagttcg aagctgataa tatcgatcag atggaagcgg ttgggcgtta
     1981 tttagggcgt atgcaccaga cggggcgcaa acagcttttt atccatcgcc cgaccatcgg
     2041 tttgaacgaa tatctcattg agccacgcaa gctgtttgag gacgctacac tgataccttc
     2101 cgggttgaaa gcggcattcc tgaaagcgac agatgagctg attgccgccg ttacagcaca
     2161 ctggcgggaa gatttcaccg ttctgcggct acatggagac tgccacgccg ggaatattct
     2221 ctggcgcgat ggtccaatgt ttgttgatct ggatgatgca cgtaatggtc cagccgttca
     2281 ggatttgtgg atgttgctca atggcgataa agccgagcag cggatgcaac tggaaactat
     2341 tattgaagct tatgaagaat ttagcgagtt cgacaccgct gaaatcggac tgattgaacc
     2401 tttacgcgcc atgcgtttgg tttattatct tgcctggcta atgcggcgtt gggctgatcc
     2461 cgcgttcccg aaaaatttcc cgtggttaac cggggaagat tactggctgc gacagacggc
     2521 gacttttata gaacaggcaa aagttctaca agaaccccct ttgcaattaa cacctatgta
     2581 ttaatcggag agagtagatc atgaaaaaga tttggctggc gctggctggt ttagttttag
     2641 cgtttagcgc atcggcggcg cagtatgaag atggtaaaca gtacactacc ctggaaaaac
     2701 cggtagctgg cgcgccgcaa gtgctggagt ttttctcttt cttctgcccg cactgctatc
     2761 agtttgaaga agttctgcat atttctgata atgtgaagaa aaaactgccg gaaggcgtga
     2821 agatgactaa ataccacgtc aacttcatgg gtggtgacct gggcaaagat ctgactcagg
     2881 catgggctgt ggcgatggcg ctgggcgtgg aagacaaagt gactgttccg ctgtttgaag
     2941 gcgtacagaa aacccagacc attcgttctg cttctgatat ccgcgatgta tttatcaacg
     3001 caggtattaa aggtgaagag tacgacgcgg cgtggaacag cttcgtggtg aaatctctgg
     3061 tcgctcagca ggaaaaagct gcagctgacg tgcaattgcg tggcgttccg gcgatgtttg
     3121 ttaacggtaa atatcagctg aatccgcagg gtatggatac cagcaatatg gatgtttttg
     3181 ttcagcagta tgctgataca gtgaaatatc tgtccgagaa aaaataattc aatgtaaatt
     3241 acataaagcc cgtgaatatt cacgggcttt ttttattatt taataaatat aaatacattc
     3301 tgataatgca tcctgccgct ggacattatt tcagcataag tggatattca aagttttgct
     3361 gttttatcag ggaatattta tatgatacgt aagtcagcta caggtgttat tgttgcgtta
     3421 gccgtaatct ggggtggtgg cacatggtac acaggtacgc aaattcagcc tggtgtcgaa
     3481 aaatttatta aagattttaa cgatgctaaa aagaaaggtg aacatgccta cgatatgacg
     3541 ttaagttatc aaaattttga caaaggcttt tttaattccc gttttcaaat gcaaatgaca
     3601 ttcgataacg gtgcacccga tctcaatatc aagccaggcc agaaagttgt atttgatgtg
     3661 gatgttgagc acggtccgtt gcccatcaca atgttaatgc atggtaatgt catcccagca
     3721 ctggcagcgg caaaagtgaa cttagtgaat aatgaactga cacaaccgct atttatcgcc
     3781 gcgaaaaata aatcgcccgt ggaagcgaca ttgcgattcg cgtttggtgg ctcattctct
     3841 acgacattag atgttgcccc tgcagagtat ggaaagtttt cttttggtga gggccagttt
     3901 acttttaatg gtgatggtag ttcattgtct aacctggata ttgaaggcaa agtcgaagat
     3961 attgttctgc aattatcacc aatgaacaaa gtaacggcaa aaagttttac cattgattct
     4021 ctggcgcgat tagaagaaaa gaaatttccg gttggtgaaa gcgagtcgaa atttaatcag
     4081 attaacatta tcaatcacgg ggaagacgtt gcccaaatcg atgctttcgt tgcaaaaacc
     4141 aggctggatc gcgttaaaga caaagattat atcaatgtca atctcaccta cgaacttgat
     4201 aagttaacaa aagggaatca gcaactcggt agtggtgagt ggtcattgat tgctgaatct
     4261 attgatccct cagcagtgcg ccaatttatc atccagtata acattgcgat gcagaagcag
     4321 cttgctgcac accctgagtt agcaaacgat gaagttgctc tgcaagaagt gaatgctgca
     4381 ttgttcaaag agtatttacc gttattacaa aaaagtgagc cgaccattaa acaaccggta
     4441 agatggaaga acgcactcgg cgaactaaat gccaatctgg atatcagtat tgccgaccca
     4501 gccaaatctt catcatccac aaacaaagat atcaaatcgc tcaattttga tgtgaagtta
     4561 ccgcttaatg tcgtcacaga aaccgcaaaa cagcttaatt tatctgaagg aatggatgcg
     4621 gaaaaagcgc aaaagcaggc tgataaacaa atcagcggga tgatgacatt aggtcagatg
     4681 tttcagttaa tcacgattga caacaatacc gcctcgctgc agctgcgtta tacaccgggt
     4741 aaagttgttt ttaacggaca ggagatgagc gaagaagaat ttatgtctcg tgccggacgt
     4801 tttgttcatt aaaatactca ctcgcctctg ctcattcaga ggcgagtaaa acttacttat
     4861 tctgacgctg tgatgacatg agagacgtca gaagccggtc tttttcctgc cacaatgagt
     4921 tcagccattg ctgaaaatgg cgcttaaagc ttttgtcatt gatgtagtcg ccatgtaact
     4981 catcggcaat aggctgtaaa tccacatgta cgacaatccg cgtcagttta ccgcttaaca
     5041 tatcgaagaa cggctgacgg ttattgtccg gataacacag cgtaacatta agcagtttat
     5101 cgaattgttt acccagtaca tttagcgcca tcgcaatgcc tgccgccttt ggtggcaaca
     5161 agttttgaaa agtggagtgg gtttgctgat gtttttcttg cgtgaaacgg gagccttcaa
     5221 cgaaattgac aatggtggtg ggatgcaggc gaaacttttc acaagaacgc cgagtggttt
     5281 caacatcttt accacgtcgc tccggatgac gtaataaata agcgcgggaa taacgcttca
     5341 taaacggcat atccagcgac cagcacgcca ggccaagaaa tggcacccag gccagctgtt
     5401 gcttgaggaa atatttattc atcggaatgt gcttacgaaa cagcacgcac agtacgacaa
     5461 tatctgccca actacggtgg ttacaaataa gcagatacca gttcttctta cttaaccctt
     5521 ccagcccgtg aacttcccat tgcaggtgtg ggttcagatg cagtaatacc gccagacctt
     5581 cacaccagca atacatcata aaatcacaaa aacgcgaaac ctttcgccaa atgactggca
     5641 caggtagcaa tagttttaca atcccggcaa tgatgatcgg gacggaacaa aaaatagtga
     5701 ccaaaatggt caatacgata ctcagcaaaa gggttatcgc agcgagtatt ctcgtcataa
     5761 tgaatttatt caaaaggtta gccatagaca gtgcgctaaa gaagcgcaag gcgcagattt
     5821 tagcagaaaa cgacccaaat aacggatgat
//
LOCUS       DAPGUL010000201         5850 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.205, whole genome shotgun sequence.
ACCESSION   DAPGUL010000201 DAPGUL010000000
VERSION     DAPGUL010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5850
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.205"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..4739)
                     /locus_tag="RHX21_004554"
     CDS             complement(<1..4739)
                     /locus_tag="RHX21_004554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001616597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAAR/RHS domain-containing protein"
                     /protein_id="HDV1989634.1"
                     /translation="MSEGPGGPQGATAGGTLAMRMLSQQAMVASQMKRAANDKAIAQM
                     LASKKSGPPAARLGDEIQHKSFLGALAGAVLGAIVTIAEGCLIMAACATGPYALVLVP
                     ALMYASYKASDYVEEKQNQLESWINSFCDTDGAINTGSENVKINGKPAARAAVTLPPP
                     PPPGAIPEVPQGEPSWGDIATDLLESAAEKAVPLAKAWGNAVITLTDSNAGFMDRVSA
                     GASLLFPAGPVLMEFATMVGGRGEIKKDVDFPEAGEDTALCDKENKPPRIAQGSSNVF
                     INNQPAARQGDKLECSAAIVGGSPDVFIGGEQVTYLDIQPEFPPWQRMILGGITIASY
                     LLPPAGLLGKLKNLARLGKLGNLLGKSGKLLGAKLGALLGKTGKSLKSIANKVIRWVT
                     DPVDPVTGAYCDERTDFTLGQTLPLSFTRFHSSVLPLHGLTGVGWSDSWSEYAWVREQ
                     GNRVDIISLGATLNFAFDGESDTAVNPYHAQYILRRRDDYLELFDRDALSSRFFYDAF
                     PGMRLRHPVTDDTSDDRLAHSPGDRMYMLGGMSDTASNRITFERDSQYRITGVSHTDG
                     IRLKLTYHASGYLKAIHRTDNGIQTLATYEQDARGRLTEADARLDYHLFYEYDAADRI
                     IRWSDNDQTWSRFTYDAQGRCVNVTGAEGYYNATLDYGDGCTTVTDGKGIHRYYYDPD
                     GNILREEAPDGSTTTYEWDEFHHLLARHSPAGRVEKFEYNAAHGQLSRYTAADGAEWL
                     YRYDERGLFSNITDPAGQTWTQLCDERGLPVSLVSPQGEETRLAYTAQGLLSGIFRQD
                     ERRLGIEYDHHNRPETLTDVMGREHHTEYSGHDLPVKMRGPGGQSVRLQWQQHHKLSG
                     IERAGTGAEGFRYDRHGNLLAYTDGNGVVWTMEYGPFDLPVARTDGEGHRWQYRYDKD
                     TLQLTEVINPQGESYLYVLDNCGRVTEERDWGGVVWRYRYDADGLCTARVNGLEETIL
                     YSRDAAGRLAEVISPEGKTQYAYDKSGRLTGIFSPDGTSQRTGYDERGRVNVTTQGRR
                     AIEYHYPDEHTVIRCILPPEDERDRHPDESLLKTTYRYNAAGELTEVILPGDETLTFS
                     RDEAGREVLRHSNRGFACEQGWNAAGQLTSQRAGLFPAEATWGGLLPSLVREYRYDSA
                     GNVSGVTSREDYGRETRREYRLDRNGQVTAVTASGTGLGYGEGDESYGYDSCGYLKAQ
                     SAGRHRISEETERYAGGHRLKQAGNTQYDYDAAGRMVSRTKHRDGYRPETERFRWDSR
                     DQLTGYCSAQGEQWEYRHDASGRRTEKRCDRKKIRFTYLWDGDSIAEIREYRDDKLYS
                     VRHLVFNGFELISQQFSRVRQPHPSVAPQWVTRTNHAVSDPTGRPLMLFNSEGKTVWR
                     PGQTSLWGLALSLPADTGYPDPRGELDPEADPGLLYAGQWQDAESGLCYNRFRYYEPE
                     TGMYLVSDPLGLLGGEQTYRYVPNPCGWVDPLGLAASSKISSLMDYIGDGRRVSGHTG
                     FLDGVRLSRSQINNIAKEMEKLGIKVIRKADKYLPPNARAAFDYGLRNIYLRKNATLY
                     EVYHEVIHAKQFAKIGREAYEALGRLS"
     gene            complement(4759..5220)
                     /locus_tag="RHX21_004555"
     CDS             complement(4759..5220)
                     /locus_tag="RHX21_004555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DcrB-related protein"
                     /protein_id="HDV1989635.1"
                     /translation="MQFTFNEGHIQLPSQWQDQSMQVLVSTDNSGINLVITREAVPQG
                     TLTPELYQETLALYQGKLDGYTEHACREITLAEAPAWLLDYSWNGPEDEGNQGRISQI
                     AVFQRRGDTLLTFTFSTSLSLKNSQKTMLLEVIKSFTPLPPENDIQKDQPR"
     gene            complement(5248..>5850)
                     /locus_tag="RHX21_004556"
     CDS             complement(5248..>5850)
                     /locus_tag="RHX21_004556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989636.1"
                     /translation="DFLNGDPDQPIIMGRTYHQENRTPGSLPGTKTQMTIRSKTYMGS
                     GFNELKFDDATGREQVYIHAQKNMDTEVLNDRTTTVKHDHRETVKNDQTVTIQEGNRL
                     LTVEKGHKITGVLKGSLSEDVFQDRGTIAGSVHVDAVNNGGEGDGIQAYTAIKEILLA
                     VEESKIALTPDGIQLQVGESTVIRLSKDGITIVGGSVFIN"
BASE COUNT         1057 a         1802 c         1584 g         1407 t
ORIGIN      
        1 ctagataaac gtcctagtgc ttcgtatgct tctcgtccaa ttttcgcaaa ttgcttagca
       61 tgaatcactt catgatacac ctcatataag gtagcatttt tcctaagata aatattgcga
      121 aggccataat caaaagctgc cctagcattt ggtggcaaat atttatctgc tttccttatt
      181 actttaattc ctagcttctc catttcttta gcaatattgt ttatttgact acgtgataaa
      241 cgaaccccat ccaggaaacc cgtatgccca ctaacacgac gaccatcgcc aatatagtcc
      301 atcaaactgc tgattttaga acttgcagcc aatcccagcg gatcaaccca cccacaagga
      361 ttcggcacat accggtaagt ctgctccccg cccagcaacc ccagcggatc actcaccagg
      421 tacattccgg tttccggctc gtaataccgg aaccggttat agcacagccc tgattccgca
      481 tcctgccact gtcctgcata cagcaggccg gggtcggctt ccgggtccag ttccccgcgc
      541 gggtccgggt agccggtgtc tgcgggcaga ctgagtgcca gcccccacag gctggtctgc
      601 cccggtcgcc agacggtttt accttcactg ttaaagagca tcagcgggcg gcccgtcggg
      661 tcgctcaccg cgtgattcgt ccgcgtcacc cactgcgggg ccacggacgg gtgcggctgc
      721 cgtacccggc tgaactgctg gcttatcagc tcaaagccgt taaacaccag gtgccttacg
      781 ctgtacagtt tatcatcgcg gtattcccgg atttccgcaa tactgtcgcc gtcccacaga
      841 tacgtgaagc ggattttctt ccggtcgcag cgtttctctg ttcgtctgcc gctggcgtcg
      901 tggcggtatt cccactgctc accctgtgcg ctgcaatacc cggtcagctg gtcacggctg
      961 tcccaccgga accgctctgt ttccgggcga tagccgtcac ggtgttttgt ccggctgacc
     1021 atccggcctg cggcgtcata gtcatactgc gtgtttccgg cctgtttcag ccggtggcct
     1081 ccggcatacc gctcagtctc ttcacttatc cggtgcctgc ccgcagactg cgccttcagg
     1141 tagccacaac tgtcatagcc ataggactca tcgccttcgc catagcccag cccggtgcct
     1201 gaggctgtca ccgccgtgac ctggccgttc cggtccagcc ggtattcccg ccgtgtttcc
     1261 cgtccgtaat cttcccggct ggtgacgcct gacacattac ccgcgctgtc gtaacggtac
     1321 tcccgtacca gtgaggggag cagcccgccc catgtggctt ctgccgggaa aagtccggcg
     1381 cgctggctgg taagctgacc ggctgcattc cagccctgtt cacaggcaaa accccggtta
     1441 ctgtgccgga gcacttcacg tcccgcctca tcacggctga acgtcagcgt ctcatccccc
     1501 ggcaggataa cctccgtcag ttctccggcg gcgttgtaac ggtaggtggt tttcagcagg
     1561 gattcatcgg gatgtctgtc gcgttcatct tccggtggca ggatacagcg gatgacggtg
     1621 tgttcgtcgg ggtagtggta ttcaatggcc cgtcggccct gagtggtgac attcacccgc
     1681 ccgcgttcgt cgtagccggt gcgctgtgat gtgccgtccg ggctgaagat acccgtcagc
     1741 ctgccggatt tgtcataggc atactgcgtt ttcccttccg gcgagatgac ttctgccagg
     1801 cggcctgcgg catcccggct gtagaggatg gtttcctcca ggccgttaac cctggcggta
     1861 cagaggccat cggcgtcata gcggtaacgc cagaccacgc cgccccagtc acgctcttcc
     1921 gtcacccggc cgcagttatc cagaacataa aggtatgatt cgccctgcgg gttaatgact
     1981 tctgtcagtt gcagcgtgtc tttatcgtag cggtactgcc agcggtggcc ttcaccgtcc
     2041 gttcgcgcca ccggcaaatc aaacgggccg tactccattg tccagacaac accgttaccg
     2101 tccgtgtacg ccagcaggtt gccgtggcgg tcatagcgga atccttccgc gccggttcca
     2161 gcacgttcaa tgccgctcag tttatggtgc tgctgccact gtaaccgcac tgactgaccg
     2221 ccggggccgc gcatcttcac cggcaggtcg tgaccgctgt attcggtgtg gtgttcacgg
     2281 cccatcacgt cggtgagtgt ttccggccgg ttgtggtggt cgtactctat gcccagacgc
     2341 cgttcatcct ggcggaatat tcccgacaac agcccctgag cggtgtacgc cagccgggtc
     2401 tcttcgccct gtggcgacac caggcttacc ggcaggccgc gttcatcgca cagctgtgtc
     2461 cacgtctgcc cggcagggtc ggtgatgttg ctgaacaggc cgcgctcatc atagcggtac
     2521 aaccactccg cgccgtctgc cgccgtgtaa cggcttaact gaccgtgtgc ggcgttgtat
     2581 tcaaacttct ccacccgccc ggcaggggag tggcgggcca gcaggtgatg gaattcatcc
     2641 cattcatacg tggtggtgct gccgtccggc gcttcttccc gcagaatatt gccgtcagga
     2701 tcatagtaat aacggtgaat gcccttgccg tccgtcacgg tggtgcagcc gtcaccatag
     2761 tccagcgtgg cgttgtaata gccctccgcc ccggtgacat tcacgcaccg gccctgtgca
     2821 tcgtaggtga aacggctcca cgtctggtcg ttatcggacc agcggatgat ccggtccgca
     2881 gcgtcgtact cataaaacag gtggtagtcc agccgcgcat ccgcttctgt cagccgcccc
     2941 cgcgcatcct gttcgtaggt cgccagcgtc tgtatgccgt tatccgtgcg gtgaatggct
     3001 ttcaggtagc cgctggcatg gtacgtcagt ttaagccgga tcccgtcggt gtgactgaca
     3061 cccgtgatcc ggtactggct gtcgcgctca aacgtgatgc ggttgctggc ggtgtcactc
     3121 atcccgccca gcatatacat ccggtcaccg gggctgtgtg ccaggcggtc atcgctggta
     3181 tcgtcagtca ccgggtggcg cagacgcatt cccggaaagg cgtcataaaa gaagcggctg
     3241 ctcagggcat cacggtcgaa cagctccagg taatcatcac ggcggcgcag gatgtactgg
     3301 gcgtgatacg ggttaaccgc cgtatcactt tcaccgtcga aggcgaagtt cagcgtggct
     3361 cccaggctga tgatatccac ccggtttccc tgttcacgca cccaggcgta ttcgctccag
     3421 gagtcgctcc agcccacgcc ggtcaggcca tgcagcggca gtacagaact gtggaaacgg
     3481 gtgaaggaga gggggagtgt ctggcccagg gtgaagtcgg tacgttcgtc gcagtacgcg
     3541 ccggttaccg gatcgacagg atctgttacc catctgatga ctttattggc aatacttttt
     3601 aacgacttac ctgttttccc cagcaacgcg ccgagctttg cccccagcag cttcccgctt
     3661 ttccccagca ggttccccag tttgccgagt ctcgccagat tcttcagttt tcccagcagt
     3721 cccgctggcg gcagaagata gctggctatc gttattcccc ccaggatcat tctctgccac
     3781 ggcgggaact ccggctggat atccagatag gtcacctgct caccgccaat aaagacgtcc
     3841 ggcgaacctc ccacgattgc tgcgctgcac tccagtttgt cgccctggcg tgcggcaggc
     3901 tgattgttga taaagacgtt gctgctgccc tgggctatcc tcggtggttt gttctccttg
     3961 tcgcagagcg ccgtgtcctc accggcttcc gggaaatcca catctttttt gatttcgcca
     4021 cgcccgccca ccatggtggc aaactccatt aataccggac cggcgggaaa cagaagcgat
     4081 gcgccggcgc tgacgcgatc cataaaaccg gcattgctgt ccgtcagggt gataacagcg
     4141 ttcccccagg ccttcgccag tggtactgct ttttccgctg ccgattcaag caggtcagtg
     4201 gcaatatcac cccatgaggg ttccccctgt gggacttcag gtattgctcc aggtggggga
     4261 ggagggggaa gggtgacggc ggccctggca gcgggctttc cgttaatttt tacgttttca
     4321 gaaccggtat tgatggcgcc gtccgtgtca caaaaactgt ttatccatga ctcaagctgg
     4381 ttctgtttct cctccacata atcactcgcc ttatagctgg catacatcag cgcaggcacc
     4441 agaaccagcg cataagggcc ggtggcacag gcggccataa tcaggcaacc ttctgcgatg
     4501 gtcactatcg cccccagcac ggcccctgcc agcgccccca aaaaactctt gtgctgaatt
     4561 tcatcgccca gcctggcggc gggggggcca gacttttttg atgccagcat ctgtgcaatg
     4621 gctttgtcgt tggctgcccg tttcatctgg ctggcgacca tcgcctgctg tgacagcatt
     4681 cgcattgcca gcgtaccgcc tgcggtcgct ccctgtggcc cgcctggtcc ttcactcatg
     4741 tgttatccct cgtttatgtc agcgcggctg gtccttttgg atgtcattct ccggtggcaa
     4801 cggggtgaag ctctttatca cctccagcag catcgtcttt tgactgttct tcagggataa
     4861 ggaggtgctg aaagtgaagg tcagcagcgt atctccacgc cgctggaata cggctatctg
     4921 gctaatccgc ccctgattcc cctcatcttc cggaccgttc caggaataat ccagcagcca
     4981 ggccggggcc tctgccagag tgatttcccg gcaggcatgt tcggtatacc catcaagttt
     5041 gccctggtac agcgccagcg tttcctggta cagctctggt gtcagggttc cctgtggaac
     5101 ggcttcgcgg gtaatgacca ggttgatgcc actgttatct gtggacacca ggacctgcat
     5161 tgactgatcc tgccattgag acggcagttg aatgtggcct tcattaaaag tgaactgcat
     5221 aaaatactcc ctgataatct gagtgaatca gttgatgaaa acagaaccgc ccacgatggt
     5281 gatgccatcc ttcgacagcc tgattaccgt cgattccccg acctgtagct gaatgccatc
     5341 cggcgtcagc gcaattttgc tttcctccac ggccagcaaa atttccttaa tcgccgtata
     5401 agcctgtata ccgtcgcctt cgccaccatt gtttacagcg tcaacatgca ccgaaccggc
     5461 aatcgtgcct ctgtcctgaa agacatcctc agataaagac cctttcagta ctccggtgat
     5521 cttgtggcct ttttccaccg taagaaggcg gttaccttcc tggatcgtga ccgtctggtc
     5581 attttttacg gtttcgcggt gatcgtgttt tacggtggtg gtacggtcgt tgagcacttc
     5641 ggtatccatg ttcttctgcg cgtggatgta gacctgttct ctccctgtcg catcatcaaa
     5701 cttcagctca ttaaatccgc tgcccatgta cgttttggag cggatggtca tctgcgtctt
     5761 tgttcccggc aggctgccgg gggtgcggtt ttcctggtgg taggtgcgcc ccataatgat
     5821 cggctggtcc ggatcgccgt tgaggaagtc
//
LOCUS       DAPGUL010000202         5653 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.206, whole genome shotgun sequence.
ACCESSION   DAPGUL010000202 DAPGUL010000000
VERSION     DAPGUL010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5653
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.206"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            100..1149
                     /gene="sohB"
                     /locus_tag="RHX21_004557"
     CDS             100..1149
                     /gene="sohB"
                     /locus_tag="RHX21_004557"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease SohB"
                     /protein_id="HDV1989637.1"
                     /translation="MELLSEYGLFLAKIVTVVLAIAAIAAIIVNVAQRNKRQRGELRV
                     NNLSEQYKEMKEELAAALMDSHQQKQWHKAQKKKHKQEAKAAKAKAKLGEVATDSKPR
                     VWVLDFKGSMDAHEVNSLREEITAVLAAFKPQDQVVLRLESPGGMVHGYGLAASQLQR
                     LRDKNIPLTVTVDKVAASGGYMMACVADKIVSAPFAIVGSIGVVAQMPNFNRFLKSKD
                     IDIELHTAGQYKRTLTLLGENTEEGREKFREELNETHQLFKDFVKRMRPSLDIEQVAT
                     GEHWYGQQAVEKGLVDEINTSDEVILSLMEGREVVNVRYMQRKRLIDRFTGSAAESAD
                     RLLLRWWQRGQKPLM"
     gene            complement(1185..1436)
                     /locus_tag="RHX21_004558"
     CDS             complement(1185..1436)
                     /locus_tag="RHX21_004558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciN family protein"
                     /protein_id="HDV1989638.1"
                     /translation="MNKETQPIDRETLLKEANKIIREHEDTLAGIEATGVTQRNGVLV
                     FTGDYFLDEQGLPTAKSTAVFNMFKHLAHVLSEKYHLVD"
     gene            1816..4413
                     /gene="topA"
                     /locus_tag="RHX21_004559"
     CDS             1816..4413
                     /gene="topA"
                     /locus_tag="RHX21_004559"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HDV1989639.1"
                     /translation="MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSAA
                     KKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEK
                     ADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNID
                     RVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEE
                     FWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPT
                     TSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNM
                     VRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQ
                     LIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRIL
                     PAVNKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRG
                     YVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDH
                     FFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYAL
                     PPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHV
                     CGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTR
                     KILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVE
                     ELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYV
                     DGKWVEGKK"
     gene            4623..5597
                     /gene="cysB"
                     /locus_tag="RHX21_004560"
     CDS             4623..5597
                     /gene="cysB"
                     /locus_tag="RHX21_004560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012017585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator CysB"
                     /protein_id="HDV1989640.1"
                     /translation="MKLQQLRYIVEVVNHNLNVSSTAEGLYTSQPGISKQVRMLEDEL
                     GIQIFSRSGKHLTQVTPAGQEIIRIAREVLSKVDAIKSVAGEHTWPDKGSLYIATTHT
                     QARYALPNVIKGFIERYPRVSLHMHQGSPTQIADAVSKGNADFAIATEALHLYEDLVM
                     LPCYHWNRAIVVTPDHPLAGKKAITIEELAQYPLVTYTFGFTGRSELDTAFNRAGLTP
                     RIVFTATDADVIKTYVRLGLGVGVIASMAVDPVADPDLVRVDAHDIFSHSTTKIGFRR
                     STFLRSYMYDFIQRFAPHLTRDVVDAAVALRSNEEIEVMFKDIKLPEK"
BASE COUNT         1500 a         1299 c         1496 g         1358 t
ORIGIN      
        1 ctttgtcata ctttcgctgc aataacatct ctgcgagacg gcttaacatg cctgttgtaa
       61 actgtgagcc aaagcgttgt ttaaccaagg tggggactcg tggaattgtt gtctgaatat
      121 ggtttgtttt tggcgaaaat cgttaccgtt gtgctagcga ttgcggcgat tgccgccatt
      181 attgtcaatg ttgctcaacg taataaacgc cagcgtggcg agttacgggt caacaatctc
      241 agcgaacagt ataaggagat gaaagaagaa ctggccgcgg cgctgatgga ctcacatcag
      301 caaaaacagt ggcacaaagc gcagaagaaa aagcacaagc aagaagcgaa agcagcaaaa
      361 gcgaaagcca aactgggcga ggtggcaact gacagtaaac ctcgcgtctg ggtgctggat
      421 tttaaaggca gcatggacgc ccatgaagtg aactcgctac gtgaagagat aacggcggta
      481 ctcgcagcat tcaaaccgca ggatcaggtt gtgctccgtc tggaaagccc tggtggcatg
      541 gtgcatggtt acgggttggc ggcttcgcag ctgcagcgtc tgcgtgataa aaacattcct
      601 ttaactgtta cggtagacaa agtcgctgcc agcggcggtt acatgatggc ctgtgtggcg
      661 gacaaaattg tttccgcacc gtttgctatt gtgggttcca ttggggtggt ggcgcaaatg
      721 cccaacttta accgcttcct gaaaagcaaa gatattgata tcgaactgca cactgccggg
      781 cagtataagc gtactctgac gttgctgggt gaaaataccg aagaagggcg ggagaaattc
      841 cgcgaagagt tgaacgaaac gcatcagttg tttaaagatt ttgtgaagcg tatgcgtccg
      901 tctctggata ttgaacaggt ggcaacgggt gaacactggt acggacaaca ggcggtagag
      961 aaaggcctgg ttgatgaaat caacaccagt gatgaagtta ttcttagcct gatggaaggc
     1021 cgtgaagtgg ttaatgtacg ctatatgcag cgtaaacgac tcattgaccg attcaccggc
     1081 agcgcggcag agagcgccga tcgattgttg ctacgctggt ggcagcgggg tcaaaagcca
     1141 ttgatgtaaa agacaaacgc gaggctaaga cctcgcgttt tgctttaatc aaccagatga
     1201 tatttttctg aaagcacatg ggccaggtgt ttgaacatat taaacaccgc ggtgcttttg
     1261 gctgttggca atccttgttc atctaaaaag tagtcgccgg taaataccag cacgccatta
     1321 cgctgcgtga cgccggtggc ttcaatccct gcgagcgtat cctcatgctc acgaatgatt
     1381 ttgttggcct ctttcaacag cgtttcgcgg tcgatgggtt gtgtctcttt gttcattatt
     1441 tactccttaa acaaggacat tagtctacgc caggcatggc ttgcagacaa atataccacg
     1501 ctggtggcaa gagcgcctta ctggtaactt tggattttgc atgctaataa agttgcgtat
     1561 cggattttat caggtacagt gtgacgcttt cgtcaatctg gcaatagatt tgcttgacat
     1621 tcgaccaaaa ttccgtcgtg ctatagcgcc tgtaggccaa gacctgttaa ctcagtcacc
     1681 tgaattttcg tgaacagagt cacgacaagg ggttgatatc cgcagagaac gagtccatat
     1741 cggtaactcg ttgccagtgg aaggtttatc aacgtgcgac gcattcctgg aagaatcaaa
     1801 ttaggtaagg tgaatatggg taaagctctt gtcatcgttg agtccccggc aaaagccaaa
     1861 acgatcaaca agtatctggg tagtgactac gtggtgaaat ccagcgtcgg tcacatccgc
     1921 gatttgccga ccagtggctc agctgccaaa aagagtgccg actctacctc caccaagacg
     1981 gctaaaaagc ctaaaaagga tgaacgtggc gctctcgtca accgtatggg ggttgacccg
     2041 tggcacaatt gggaggcgca ctatgaagtg ttgcctggta aagagaaggt cgtctctgaa
     2101 ctgaaacaac tggctgaaaa agccgaccac atctatctcg caaccgacct tgaccgcgaa
     2161 ggggaagcca ttgcatggca cctgcgggaa gtgattggtg gtgatgatgc gcgctatagc
     2221 cgagtggtgt ttaacgaaat tactaaaaac gcgatccgcc aggcatttaa caaaccgggt
     2281 gagctgaata ttgatcgtgt taatgcccag caggcgcgtc gctttatgga ccgcgtggtt
     2341 gggtatatgg tttcgccgct gctatggaaa aagatcgctc gtggtctgtc tgccggtcgt
     2401 gtgcagtcgg tggcggttcg cctggtggtc gagcgtgagc gtgaaattaa agcgttcgtg
     2461 ccggaagagt tctgggaagt cgatgccagc acgaccacgc catctggtga agcgttggcg
     2521 ttgcaggtga ctcatcagaa cgacaaaccg ttccgtccgg tcaacaaaga acaaactcag
     2581 gctgcggtaa gtctgctgga aaaagcgcgc tacagcgtgc tggaacgtga agacaaaccg
     2641 acaaccagta aacctggcgc tccttttatt acctctacgc tgcaacaagc tgccagcacc
     2701 cgtcttggat ttggcgtgaa aaaaaccatg atgatggcgc agcgtttgta tgaagcaggc
     2761 tatatcactt acatgcgtac cgactccact aacctgagtc aggacgcggt aaatatggtt
     2821 cgcggttata tcagcgataa ttttggtaag aaatatctgc cggaaagtcc gaatcagtac
     2881 gccagcaaag aaaactcaca ggaagcgcat gaagcgattc gtccttctga cgtcaatgtg
     2941 atggcggaat cgctgaagga tatggaagca gatgcgcaga aactgtacca gttaatctgg
     3001 cgtcagttcg tagcctgcca gatgacccca gcgaaatatg actccacgac gctgaccgtt
     3061 ggtgcgggcg atttccgcct gaaagcacgc ggtcgtattt tgcgttttga tggctggaca
     3121 aaagtgatgc ctgcgttgcg taaaggcgat gaagatcgca tcttaccagc agttaataaa
     3181 ggcgatgctc tgacgctcgt tgaacttaca ccagcccagc actttaccaa gccgccagcc
     3241 cgtttcagtg aagcatcgct ggttaaagag ctggaaaaac gtggtatcgg tcgtccgtct
     3301 acctatgcgt cgatcatttc gaccattcag gatcgtggct acgtgcgagt agaaaatcgt
     3361 cgtttctatg cggaaaaaat gggcgaaatc gtcaccgatc gccttgaaga aaatttccgc
     3421 gagttaatga actacgactt taccgcgcag atggaaaaca gcctcgacca agtggcaaat
     3481 cacgaagcag agtggaaagc tgtactggat cacttcttct cggatttcac ccagcagtta
     3541 gataaagctg aaaaagatcc ggaagagggt ggtatgcgcc cgaaccagat ggttctgacc
     3601 agcattgact gcccgacttg tggtcgcaaa atggggattc gcacagcgag caccggggta
     3661 ttccttggct gttctggcta tgcgctgccg ccgaaagagc gttgcaaaac caccattaac
     3721 ctggtgccgg aaaacgaagt gctgaacgtg ctggaaggcg aagatgctga aaccaacgcg
     3781 ctgcgcgcaa aacgtcgttg cccgaaatgc ggcacggcga tggacagcta tctcatcgat
     3841 ccgaaacgta agttgcatgt ctgtggtaat aacccaacct gcgacggtta cgagatcgaa
     3901 gagggcgaat tccgcattaa aggttatgac ggcccgatcg ttgagtgtga aaaatgtggc
     3961 tctgaaatgc acctgaaaat ggggcgtttc ggtaaataca tggcctgcac caacgaagag
     4021 tgtaaaaaca cacgtaagat tttacgtaac ggcgaagtgg caccaccgaa agaagatccg
     4081 gtgccattac ctgagctgcc gtgcgaaaaa tcagatgctt atttcgtgct gcgtgacggt
     4141 gctgccggtg tgttcctggc tgccaacact ttcccgaaat cgcgtgaaac gcgtgcgcca
     4201 ctggtggaag agctttatcg cttccgcgac cgtctgccgg aaaaactgcg ttatctggcc
     4261 gatgcgccac agcaggatcc ggaaggtaat aagaccatgg ttcgctttag ccgtaaaacc
     4321 aaacagcaat atgtctcttc ggaaaaagac ggaaaggcga ctggctggtc agcattttat
     4381 gttgatggca aatgggttga aggaaaaaaa taacctttaa ttctgtcagg tttttataaa
     4441 caaagggtcg cgaaagcggc ccttttttat tgcatattat tttttcttca cacctataca
     4501 ctaaggctat aaatgatata gtggttatag ttagcacctt ttttattatt aaatcgtatt
     4561 agtcacccgc caggtgtgac gaaaaaacga tgttctgatg gcgtctaagt ggatggttta
     4621 acatgaaatt acaacaactt cgctatattg ttgaggtggt caatcataac ctgaatgtct
     4681 catcaacagc ggaaggactt tacacatcac aacccgggat cagtaaacaa gtcagaatgc
     4741 tggaagacga gctaggcatt caaatttttt cccgaagcgg caagcacctg acgcaggtaa
     4801 cgccagcagg acaagaaata attcgtatcg ctcgcgaagt cctgtcgaaa gtcgatgcca
     4861 taaaatcggt tgccggtgag cacacctggc cggataaagg ctcgctgtat atcgccacca
     4921 cgcataccca ggcacgctac gcgttaccaa acgttatcaa aggctttatt gagcgttatc
     4981 cccgcgtttc tttgcatatg caccagggct cgccgacaca aattgctgat gccgtctcta
     5041 aaggcaatgc tgatttcgct atcgccacag aagcgctgca tctgtatgaa gatttagtga
     5101 tgttaccgtg ctaccactgg aatcgggcta ttgtagtcac tccggatcac ccgctggcag
     5161 gcaaaaaagc cattaccatt gaagaactgg cgcaatatcc gttggtgaca tataccttcg
     5221 gctttaccgg acgttcagaa ctggatactg cctttaaccg cgcagggtta acgccgcgta
     5281 tcgtcttcac ggcaacggat gctgacgtca ttaaaactta cgtccggtta gggctggggg
     5341 taggggtcat tgccagcatg gcggtggatc cggtcgccga tcccgacctt gtgcgtgttg
     5401 atgctcacga tatcttcagc cacagtacaa ccaaaattgg ttttcgccgt agtactttct
     5461 tgcgcagtta tatgtatgat ttcattcagc gttttgcacc gcatttaacg cgtgatgtcg
     5521 ttgatgcggc tgtcgcattg cgctctaatg aagaaattga ggtcatgttt aaagatataa
     5581 aactgccgga aaaataattt cttgcgttat tttcggcacc ttttatgtag cgaaggtgcc
     5641 ggaatatatt ctc
//
LOCUS       DAPGUL010000203         5564 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.207, whole genome shotgun sequence.
ACCESSION   DAPGUL010000203 DAPGUL010000000
VERSION     DAPGUL010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5564)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5564)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5564
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.207"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..2414
                     /locus_tag="RHX21_004561"
     CDS             <1..2414
                     /locus_tag="RHX21_004561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010344508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HDV1989641.1"
                     /translation="HANTITLKSDSWLNIDTSIKNWTQDYYTLLSSDTGISIADNSHI
                     VQYNVLLTEGAESYVYTSLNDDDNKLISMLRWNNTKGMGYGTFNIEKDATLNIGVSLS
                     DNLSPLLYDGWDGKSLTKSGNGTLILSATNNYTGNTEVKSGVLILAAPDALGRTEYLY
                     LSRGAELDMNGYPQTISKLLTAAGSVLNIHGGSLILNNGGESAGTIAGDGSLNINGGM
                     LDITGNNRNFSGVFTVNKGAHLAVSTADNLGTAFVDNYGTLTLNSTSAWQLTNNISGY
                     GNVRKTGAGALNISDNAKWTGMTDIIQGTVILGNADSPVMLGSNQVIVEEQGKLSGFG
                     GVAGNLSNSGIVDLTTYMPGNILTVGGNYTGRNGLILLQTETGGDNSKTDRLVIKGNA
                     SGRTRVAVTQAGGTGAETLNGIEVIHVSGNADNAEFIQTERITAGAYDYILKRGQGIN
                     STNWYLISRKDIPVPQPEAVPENHDNNLRPEAGSYVASIAAANNLFVTNLYERQGQEL
                     YISHMTGEENEAGIWMYNKGKHNRWRDNSSQLRTRGNSYVVLIGGDIAQWSLNGTDRW
                     HTGMMAGYGHNNNSTNALSTGYHSEGRMNGYTAGLYATWYANDETHNGSYLDSWLQYS
                     WFDNHINGERLPAESWKSKGFTVSLEAGYSWKAGEFTDNYKGSHEWYVQPQLQVVRMN
                     VKSDKYHESNGTSIENTGNGNILTRLGARTWLTSKNGKNTRYAVPFRPFVEAHWLHNS
                     RVFGTSMNGVSIYQDGARDIGEINGGVVGMITPEVAFRADAGIQLGEHGYHNTSAMLS
                     VKYRF"
     gene            complement(2589..2794)
                     /locus_tag="RHX21_004562"
                     /pseudo
     CDS             complement(2589..2794)
                     /locus_tag="RHX21_004562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015869530.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2784..2990
                     /locus_tag="RHX21_004563"
     CDS             2784..2990
                     /locus_tag="RHX21_004563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000896261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase"
                     /protein_id="HDV1989642.1"
                     /translation="MAFVSDSDDSYRWNEVDKRFSVDDTPNEPNRFGWVGEIDPYGYF
                     SENNENICALYNQIKPRNKHKYYR"
     gene            3448..3696
                     /locus_tag="RHX21_004564"
                     /pseudo
     CDS             3448..3696
                     /locus_tag="RHX21_004564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612015.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            3761..4912
                     /locus_tag="RHX21_004565"
     CDS             3761..4912
                     /locus_tag="RHX21_004565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004389801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS30 family transposase"
                     /protein_id="HDV1989643.1"
                     /translation="MRRTFTAEEKASVFELWKNGTGFSEIANILGSKPGTIFTMLRDT
                     GGIKPHERKRAVAHLTLSEREEIRAGLSAKMSIRAIATALNRSPSTISREVQRNRGRR
                     YYKAVDANNRANRMAKRPKPCLLDQNLPLRKLVLEKLEMKWSPEQISGWLRRTKPRQK
                     TLRISPETIYKTLYFRSREALHHLNIQHLRRSHSLRHGRRHTRKGERGTINIVNGTPI
                     HERSRNIDNRRSLGHWEGDLVLGTKNSHIATLVDRKSRYTIILRLRGKDSVSVNQALT
                     DKFLSLPSELRKSLTWDRGMELARHLEFTVSTGVKVYFCDPQSPWQRGTNENTNGLIR
                     QYFPKKTCLAQYTQHELDLVAAQLNNRPRKTLKFKTPKEIIERGVALTD"
     gene            4922..5281
                     /locus_tag="RHX21_004566"
                     /pseudo
     CDS             4922..5281
                     /locus_tag="RHX21_004566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611483.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            5382..>5564
                     /locus_tag="RHX21_004567"
     CDS             5382..>5564
                     /locus_tag="RHX21_004567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDV1989644.1"
                     /translation="MSRKTQRYSKEFKAEAVRTVLENQLSISEGASRLSLPEGTLGQW
                     VTAAIKGLGTLGSRTVA"
BASE COUNT         1690 a         1148 c         1346 g         1380 t
ORIGIN      
        1 ttcacgcaaa tactattaca ttaaaaagtg attcatggct taatatagac acatcaatta
       61 agaactggac tcaggactat tacacattat tgtcgtcaga cacaggtatc tcgatcgctg
      121 ataatagtca cattgtacaa tacaatgtat tactgacaga aggtgctgaa agttatgttt
      181 atacgtcttt aaatgacgac gataacaaac tgatatccat gctgagatgg aataatacaa
      241 aagggatggg atatggaacc tttaatatag aaaaagatgc aactctgaac ataggcgttt
      301 ctctttccga taatctttca cctttattat atgatggctg ggacggcaaa agtctgacaa
      361 aatcaggtaa tggtactctt atactttctg caacaaacaa ttatacagga aatacagagg
      421 ttaaatctgg cgtattaatt cttgctgcac ctgatgctct tggtcggact gagtatttat
      481 atttatcccg tggcgcagaa ctggatatga atgggtatcc tcagacaata agcaaactac
      541 tgacggctgc aggctctgtg ctgaacattc atggcggaag cctgatactg aataatggag
      601 gagaatctgc aggtactatt gcaggggatg gttctctgaa cataaatggg ggaatgcttg
      661 atataacggg taataatcgt aatttttccg gtgtttttac cgtgaataag ggggctcatt
      721 tggctgtatc cacggctgat aatctgggga cagcctttgt tgataactat ggcacattaa
      781 ctctgaacag tacatcagca tggcagctta ccaacaatat cagtggttat ggtaatgttc
      841 gcaagacggg agcaggtgca ctgaacatta gcgataacgc aaaatggacc gggatgacag
      901 atattattca ggggacagtg atactgggga acgcagattc accggtgatg ctcggcagta
      961 accaggtcat tgttgaagag cagggcaaac tctccgggtt tgggggcgtt gcaggaaatc
     1021 tgagcaatag tggtatagtc gatctcacta catatatgcc gggtaatata ctgactgtcg
     1081 gagggaatta cactggcaga aatggactta ttctcctcca gacagaaaca ggtggtgaca
     1141 attcgaaaac agatcgtctg gtgattaaag gtaatgccag tggccgtacc cgtgtcgctg
     1201 ttactcaggc cggtggtact ggtgcagaga cacttaatgg gattgaagtg attcacgtca
     1261 gtggcaatgc tgataatgct gaattcattc agacggaacg tattacagcc ggagcttatg
     1321 attacatact gaaacgtggt caggggatta acagcactaa ctggtatctg attagcagaa
     1381 aagacattcc tgtaccacaa cctgaagctg taccggaaaa ccatgataat aatttgcgtc
     1441 ctgaggcagg tagctatgtt gccagtattg ctgctgcaaa taatctgttt gtaacgaatc
     1501 tgtatgaacg acagggacag gagttgtata tcagccacat gacaggagaa gaaaatgaag
     1561 caggtatctg gatgtataat aaaggaaaac ataatcgctg gcgtgacaac agtagtcagc
     1621 tgagaacccg ggggaatagc tacgttgtgt taataggggg agatatagct cagtggagcc
     1681 tgaatggtac cgatcgctgg catacaggta tgatggctgg ctatggtcat aataataaca
     1741 gtacgaatgc cctgagcacc ggataccatt cggaaggaag aatgaatgga tacacagcgg
     1801 gtctttatgc aacatggtat gccaatgatg aaacacacaa tggttcttat cttgatagct
     1861 ggctgcaata cagctggttt gataatcata taaatggaga acggctgcct gctgagtcat
     1921 ggaagtcaaa agggttcacg gtatctctgg aagcaggata ttcatggaag gctggagagt
     1981 ttaccgacaa ttacaaggga agtcatgaat ggtatgttca gccgcagctt caggttgtcc
     2041 ggatgaatgt aaaatcagac aaatatcatg aaagtaacgg aaccagtatt gaaaataccg
     2101 gtaacggaaa tattctcacc cgcctgggag caagaacatg gcttaccagc aaaaacggta
     2161 aaaatacgcg gtatgcggtt ccgttcagac catttgtgga ggcacactgg ttgcacaata
     2221 gtcgtgtttt cggcaccagt atgaatggtg taagtatata ccaggatggt gcgcgtgata
     2281 tcggagaaat aaatggtggt gttgtgggaa tgataacacc agaagtagca ttccgggctg
     2341 atgcaggcat tcaacttgga gaacatggat accataatac atctgccatg ttgagtgtga
     2401 aatatcgttt ctgatgtgtc tttacattat aaatatcctt cacaaaatat tgttgataag
     2461 acatggttag gtggtgagct gcctcggaaa atatgacgac agtaatgatt tctaagagat
     2521 ttgaaatgcg ttgataacaa aatctgaaat ataggagtct gtttaggatt gtgtgtaaat
     2581 gccttttctc aaaagtaacc gtccaggcgg tcactgaatc cgataataaa gcggcttatt
     2641 gccatacccc agtccttcaa cggcatcgtc catttcgggg acgatgcctg tattgccaga
     2701 cacaccactt ttttcaccgg ctcgtctgtc ggaaacactt acgctttttg atcgcatggc
     2761 ggatcacgct gtttagcgac ccgatggcat tcgtcagcga cagcgacgac tcttaccgct
     2821 ggaacgaagt ggataagcgc ttcagtgtcg acgacacgcc gaacgagccg aaccgcttcg
     2881 gctgggtggg ggaaatcgat ccatatggtt atttttcaga aaataatgag aacatctgtg
     2941 ctttatataa ccagataaaa ccacgcaata agcataaata ttacaggtga taatactttt
     3001 atttatcact tcggttatat tcaataaaca taataacttt ctcttaaatc acaggtccag
     3061 ccattgcagt tgttatcaga cgtagattag gatgccagtg catttacatg ggatggtttg
     3121 tgtatccacc gggtataatg cgtgatatca ttaatttcaa cactaactgt gcgattgtct
     3181 ttcatgcctg ccctccgggc aggctttttt ctgcatgcag aaaaaaatca ccggaaaaaa
     3241 cggcagcaga taaaaaagag tgctgacagg gatattattt catccgctca ctggcgagat
     3301 gataaacgtt gctacgttca cgtttaccta ctgcgactac cgcaataatt aacatatcat
     3361 caataacctg ataaacaaga cgaatgaatc gccacaggtt taatagacac ctcagagtca
     3421 tttaagatga cttaaagaga ggtgcccatg agcggtaagc gttatcccga agagtttaaa
     3481 attgaagcag tcaaacaggt tgttgatcgc ggttattctg ttgccagcgt tgcaacacgt
     3541 ctcgatatca ccacccacag cctttactcc tggataaaga agtacggtcc ggattcttcc
     3601 actaataaag aacagtcaga tgctcaggcc gagatccgcc gtctccagaa agagctgaag
     3661 cgggttaccg acgaacggga catattaaaa aaagccgttg tagattcaat tggtcaacgc
     3721 aacagttatg tgaaaacatg gggttgcaga ggttttttga atgagacgaa catttacagc
     3781 agaggaaaaa gcctctgttt ttgaactatg gaagaacgga acaggcttca gtgaaatagc
     3841 gaatatcctg ggttcaaaac ccggaacgat cttcactatg ttaagggata ctggcggcat
     3901 aaaaccccat gagcgtaagc gggctgtagc tcacctgaca ctgtctgagc gtgaggagat
     3961 acgagctggt ttgtcagcca aaatgagcat tcgtgcgata gctactgcgc tgaatcgcag
     4021 tccttcgacg atctcacgtg aagttcagcg taatcggggc agacgctatt acaaagctgt
     4081 tgatgctaat aaccgagcca acagaatggc gaaaaggcca aaaccgtgct tactggatca
     4141 aaatttacca ttgcgaaagc ttgttctgga aaagctggag atgaaatggt ctccagagca
     4201 aatatcagga tggttaaggc gaacaaaacc acgtcaaaaa acgctgcgaa tatcacctga
     4261 gacaatttat aaaacgctgt actttcgtag ccgtgaagcg ctacaccacc tgaatataca
     4321 gcatctgcga cggtcgcata gccttcgcca tggcaggcgt catacccgca aaggcgaaag
     4381 aggtacgatt aacatagtga acggaacacc aattcacgaa cgttcccgaa atatcgataa
     4441 cagacgctct ctggggcatt gggagggcga tttagtctta ggtacaaaaa actctcatat
     4501 agccacactt gtagaccgaa aatcacgtta tacgatcatc cttagactca ggggcaaaga
     4561 ttctgtctca gtaaatcagg ctcttaccga caaattcctg agtttaccgt cagaactcag
     4621 aaaatcactg acatgggaca gaggaatgga actggccaga catctagaat ttactgtcag
     4681 caccggcgtt aaagtttact tctgcgatcc tcagagtcct tggcagcggg gaacaaatga
     4741 gaacacaaat gggctaattc ggcagtactt tcctaaaaag acatgtcttg cccaatatac
     4801 tcaacatgaa ctagatctgg ttgctgctca gctaaacaac agaccgagaa agacactgaa
     4861 gttcaaaaca ccgaaagaga taattgaaag gggtgttgca ttgacagatt gaatctacaa
     4921 ccgcgctctt gatgtcagac tccctgaaca gttctcgata atcgggaaac tcagagcgca
     4981 ttatcctgtg gtcacactct gccatgtgtt cggggttcat cgcagcagct acagatactg
     5041 gaaaaaccgt cctgaaaaac cagacggcag acgggctgta ttacgcagtc aggtacttga
     5101 gctacatggc atcagccacg gttcggccgg agcaagaagc atcgccacaa tggcaacccg
     5161 gagaggctac cagacgggac gctggcttgc tggcaggctc atgaaagagc tggggctggt
     5221 cagctgtcag cagccgactc accggtataa acgtggtggt catgaacatg ttgctatgcc
     5281 taaggttctc acgccgccat catgcagctc tgacggatga ggtagcctga gtttaacgga
     5341 cactccttcc tgaaatagaa tggcatcaga aggagctaat aatgagcaga aaaacccaac
     5401 gttactctaa agagttcaaa gccgaagctg tcagaacggt tcttgaaaat caactttcga
     5461 tcagtgaagg cgcttcccga ttatctcttc ctgaaggcac tttaggacaa tgggttaccg
     5521 ccgccataaa agggctcggt actcttggtt cccgcacggt ggct
//
LOCUS       DAPGUL010000204         5431 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.208, whole genome shotgun sequence.
ACCESSION   DAPGUL010000204 DAPGUL010000000
VERSION     DAPGUL010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5431)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5431)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5431
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.208"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            666..920
                     /locus_tag="RHX21_004568"
     CDS             666..920
                     /locus_tag="RHX21_004568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000788354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDV1989645.1"
                     /translation="MKNGIDVSVIIPAYNAAETSVSLVTKILSEPHLAIELIIVDDGS
                     TDETGNVLRQIHDDRLILIEQANQGVYAARNAALALHQGE"
     gene            2024..4099
                     /locus_tag="RHX21_004569"
     CDS             2024..4099
                     /locus_tag="RHX21_004569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000177022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDV1989646.1"
                     /translation="MDLVDSVEAGKLTISELIDALAKDKNYSASKWDQRYREFTTLLQ
                     QTSTFSEPETDGLVKRLWYERDNGIASIRQGVPSLAEYQQSLPLLRELTERIRQQPDE
                     ETYQYVGNALQQAKENGLLKRMYRSLRNRVFAAFSPENYTSTVDENAFSKAAEFLNQH
                     FHLGLALTGNWLQKNYELKQAIHAQSPDTDPYYVNMAIWHLYELLRERDNEQKQEKIA
                     STTFITSNEPIENKIILHSPTNVIFFGPPGTGKTFRLQQKMKEYTSHAVPADRDAWLD
                     SRLESLNWMQVITLVLLDLGKRAKVRQIIEHMWFQRKALLNGRNGNLSNTAWAALQSY
                     TVPESLTVDYKNRREPAVFNKTDNSEWLLVDSQLEQVEDLVELYAELKRGPKSAEAIQ
                     RFAVVTFHQSYGYEEFIEGIRARSDESGNISYPIEPGIFMRLSQRANADPGHRYAIFI
                     DEINRGNISKIFGELISLIEVDKRAGMPNAMSLQLAYSGDHFSVPANVDIIGAMNTAD
                     RSLALMDTALRRRFDFVEMMPDLSLLSGAKVKGIELESLLEKLNSRIEALYDREHTLG
                     HAFFMPVKNALDAGDEEAAFKQLKIAFQKKIIPLLQEYFFDDWNKIRLVLADNQKQDD
                     NLQFVIEKTDDLDTLFGNNHGLRHHDQQSTAYELKDFDQEIWNIPQAYRSIYQPQQTP
                     LDEQAVNHG"
     gene            4092..5378
                     /locus_tag="RHX21_004570"
     CDS             4092..5378
                     /locus_tag="RHX21_004570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000504875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HDV1989647.1"
                     /translation="MGEVISVFEYDLLGSDKAASVGAKLVPPLVFNYLEALSLASNQG
                     SQFLKLTSRSGFKLLQVQNYAGMLSTPHGFQLEILPKVGKNLTAANARQTLLTMLSHL
                     PGFRHIETQQATLQAQRMPLLEIFIHQFLHSVSQLLKQGLRSDYVSEQGNLAFMKGKL
                     MLSAQLRHNAVNRHKFCVDYDDYMPDCAANRLLHSALDKLLSLKLSSENQRWLYELRF
                     AFDGIPLSRDIERDINNLRLERGMAHYNEPMAWAQLILRGMSPSALQGNTKAISLLFP
                     MEAVFESFVAQTLPYELPSHLKVIPQAATYSLVKHGSNDCFKLRPDLLIQSRRPVQTK
                     LVMDTKWKLINSNSQKTTQYGLAQADFYQMFAYGQKYLNGIGEMYLIYPAHDQFNQPI
                     QQHFAFSKTLKLWVVPYQITANRGERMMWVKDVSSI"
BASE COUNT         1593 a         1227 c         1183 g         1428 t
ORIGIN      
        1 catgatcttt acaggaatca gcagaggaaa acatctatta ttaccatgta attcatgttg
       61 ttatgtcgca acaatagtac tgcacgggga attattacgg gcaaacttag gcgaaaggaa
      121 gtactgaagt gacagaataa atcacacttt ttgtacatat gtacttttct attgtctttt
      181 gttgtggaaa caaatagtgt ttgtcatgcc gatgctaata gacagataga ttcgagggcc
      241 aacagcccca tcatcatgat ggagcaacag aggtgagtct aacgtttccg cacttcttat
      301 cgatcggcac taacgatcaa tatcgataaa ctgatctatc aaaacgatta tctttcttgc
      361 aacctgcctg gttatccttc tcttacattg ctcgcagaaa agccctttta ttacggttag
      421 ttatctagct gagacttgct acgcccattt tccatgtacc ccaaatcacg aggtcacaaa
      481 ggcgcggaaa gatgaagaga tgtgcacgtt gcaacaaaaa aagaagcgtc cttgaacaga
      541 ggctctcact cgataaagaa ttctgcgacg agtgcttatt cgatatcgat gaggaaatca
      601 gggaaagaag gattatcacg atcagacgcc tcaaagatga caacgaaaga aaatcgtagc
      661 tcaatatgaa aaatggaatc gatgtcagcg tcattatccc tgcttacaac gccgctgaaa
      721 ccagcgttag tttggttact aaaatcctca gtgaacccca cttggctatt gaacttatca
      781 ttgtcgatga cggttctact gatgaaactg gcaacgttct tcgtcaaatc cacgatgatc
      841 ggctcattct cattgagcag gccaatcaag gtgtctatgc cgcccgaaat gctgctctag
      901 ccttgcacca aggagaatag gttatattcc ttgatgcgga cgacgatata gcagatgggt
      961 tcatagaaaa aagatggcag gcagttagta cgtcgcaagc cgacgtcatg atctttaatg
     1021 gctggcattc ctgtgctgac caacatcgaa gagcggttca caaaaagcag ccctatggta
     1081 cgcctctgtc aggttattaa tggattagac actgtgttac acaccgcgaa tggccgcatt
     1141 atctgtggct gcagatggtc aggccatcct atgtcaggca gcattcactg cgcttccagt
     1201 ccggcaggag ccataaagac attttttaaa cggttcatct tgcagcgagc aatggttgat
     1261 tctgtacatt ggatataaag gactatatct atatcaacaa taaggcctct atcacacatc
     1321 ggccggatta ctacgttgtt cgtgctataa actatgttga agtgatcgcg aaaatcatcc
     1381 aagtagcgga acaagaacaa aacaaaaaat aaaggtattt ttgtaccggc atgcgctggt
     1441 agaggcacgt cattttttgg gactctaccg caatcgcgtt ggggataaat cgggcatgaa
     1501 ggactgcttc aaagcgaaca tattcgcagc ccatttattc agaggtatca gcagttttag
     1561 cgatgtgttt ttctttatta agctgctggg caagctattc tgataagttg tgcgttgcta
     1621 cacgacacca gcgcacagct taatttcacg ctttctgact aaattgttca ggccttttct
     1681 ataggtgcaa acacaactcc ccgtactttc ctcttccaac tcaaaatcat cgcaccttgc
     1741 tgacccaaga agggagcata ccctgcacta gtatccgcac agctaatact ctattgatac
     1801 caacaacgct tcagcacaac aaagtaactc gataatcaca actcaaagtg aagatgccaa
     1861 aaactcgttt gagagcaata aattcaataa catgaaaaaa atgtattttg cattgaaaat
     1921 cttacttatt gcgcttggct acaattgcat gcttggtaat atagattata aaacaccaga
     1981 ctagctgcct ggtaagtaat gtaatagcag aggaaatatc acgatggatc ttgtagatag
     2041 tgtcgaagca ggtaagctga cgatcagtga attgattgat gccctggcga aagataaaaa
     2101 ttactcagct tccaagtggg atcagcgata ccgtgaattt acgaccttgc tacaacaaac
     2161 ctcaactttt tctgaacctg aaacggatgg tttagtcaag aggctctggt atgaacgcga
     2221 taacggtatt gccagtattc gccagggcgt tccatcctta gcagaatatc agcaaagcct
     2281 gccactgctt agagaactaa ctgaacgaat tcggcaacag ccggatgaag aaacttacca
     2341 atatgttggc aatgcactac aacaagctaa agaaaacgga cttctcaagc gtatgtatag
     2401 gagtttgaga aatcgcgtct ttgccgcgtt ctcgccagaa aactacacca gtactgtgga
     2461 tgagaatgct tttagtaaag cagcagaatt cctaaatcag cacttccatc tcggtctggc
     2521 actgaccgga aattggttac agaaaaacta tgaattgaaa caagccatac acgcccaatc
     2581 tcctgacaca gatccttatt acgtgaatat ggccatctgg catctctatg aattgctccg
     2641 tgaacgcgat aatgaacaaa agcaggagaa aatagcgagc actacattca taaccagcaa
     2701 tgagcccatc gagaacaaga tcatcctaca ttcaccaact aacgtgatct tctttggccc
     2761 ccctggcact ggcaaaacct tcaggttgca gcaaaaaatg aaagagtaca cttctcatgc
     2821 tgttccagct gatcgtgatg cctggctgga ttctcgcctt gaatcgttga attggatgca
     2881 ggttataacg ctggtgctgc tcgatcttgg gaaacgagcc aaagttcgcc aaattattga
     2941 acatatgtgg tttcaacgta aggcattatt aaacggtcgt aatggcaacc tatcgaatac
     3001 agcctgggca gctttgcaat cctatacagt tcccgagtcg ttaaccgttg attataagaa
     3061 tcggcgtgag cctgccgtat ttaacaaaac agataacagc gaatggttgc tagttgattc
     3121 acagctcgag caagtggagg atttggtaga gctctacgcc gaacttaaac gaggccctaa
     3181 atctgccgaa gccatccagc gttttgcggt ggttacgttc caccaatctt acggctatga
     3241 agaatttatt gaaggtatac gcgctcgctc tgacgagagt ggcaatatct cttatcccat
     3301 tgagccgggt atctttatgc gcctttccca acgtgccaat gccgatccag gacatcgcta
     3361 cgccattttc attgatgaga tcaatcgcgg taacatatcc aagatctttg gtgaactaat
     3421 ctcactcatt gaagtagaca agcgtgcagg catgcccaat gcaatgagcc tacaactggc
     3481 ttatagcggt gatcacttca gcgtacccgc caatgtcgat atcatcggag ccatgaatac
     3541 agcggaccgt tctttagctc tgatggacac ggctttgcgc cgtcgctttg actttgtcga
     3601 aatgatgccc gatctctctt tactgagtgg agctaaggtg aaaggcatag agctcgagtc
     3661 gttgttagag aaactcaata gccgcatcga ggctctttac gatcgtgaac atacgctggg
     3721 gcatgcgttc tttatgccgg taaaaaatgc actcgatgcc ggtgatgaag aagctgcgtt
     3781 taaacaattg aagatcgcat tccagaaaaa gatcattccg cttttacagg aatacttttt
     3841 cgatgactgg aacaagatcc ggttggtgct ggcagacaat caaaagcaag acgacaacct
     3901 gcaattcgtg attgagaaaa ccgacgatct cgatacgctt tttggtaaca accatggttt
     3961 acgacaccat gatcagcaat caacagctta cgaactcaaa gatttcgatc aagagatctg
     4021 gaatattcca caggcttatc gttcaattta tcagccccag cagactcccc ttgatgagca
     4081 ggctgtaaat catgggtgaa gttatctccg tttttgaata tgacctattg gggagtgaca
     4141 aagcggcttc agttggcgca aaactggtgc ctccactggt ctttaattat ttagaagcgc
     4201 ttagcttggc aagtaatcaa gggagccagt tcctcaaact cacctctcgc tcaggcttca
     4261 aattgcttca ggttcaaaac tacgcgggga tgctttcaac acctcacggt ttccagcttg
     4321 agatactgcc caaggttggt aaaaacctca cagcggctaa tgcacgtcaa acattactga
     4381 cgatgctaag ccatttgcct gggtttcgac atattgaaac tcagcaagcc actcttcagg
     4441 ctcagcgtat gcctttgctt gagattttta ttcaccagtt tttgcatagc gttagccaat
     4501 tacttaaaca aggtttacgc tccgactatg tgagcgagca aggtaatctg gcttttatga
     4561 agggcaagct gatgctttct gcacagctgc gacataacgc ggtgaatcgc cataagtttt
     4621 gtgtcgatta tgatgactac atgcctgatt gtgcagccaa tcggctctta cactccgcgc
     4681 tagataagct tcttagtcta aagctgtcat cagagaatca acgctggctt tacgaactgc
     4741 gctttgcgtt tgacggtatt ccacttagcc gggatattga acgtgatata aacaacttac
     4801 gcctcgagcg tggtatggct cattacaacg agccaatggc gtgggcgcaa ttgatcctga
     4861 gaggaatgag tccgagtgct ttgcagggaa acaccaaagc gatatcactt ttgttcccta
     4921 tggaagcggt atttgaatcc tttgtggcac agaccctacc ctacgaatta ccttctcatc
     4981 tcaaagtaat accacaagcg gctacttatt ctcttgtgaa gcacgggtct aacgattgct
     5041 ttaaacttcg gccggatttg ttgattcagt cacgtcgacc ggtacaaacc aaattggtga
     5101 tggacacaaa atggaagcta ataaatagca actcccaaaa aacaacacag tatgggctag
     5161 cgcaagccga cttctatcaa atgtttgcct acggtcaaaa atacctaaat gggattggcg
     5221 aaatgtactt aatctatcct gcgcatgatc aatttaacca accgatacag cagcattttg
     5281 ctttctctaa aacattaaaa ctatgggttg ttccgtacca gataacagca aaccgcgggg
     5341 agaggatgat gtgggtgaag gatgtgtcca gtatataaat ttctagccaa gctggcgatg
     5401 aaccagtcct ctaaaaaatg ggtataatca t
//
LOCUS       DAPGUL010000205         5421 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.209, whole genome shotgun sequence.
ACCESSION   DAPGUL010000205 DAPGUL010000000
VERSION     DAPGUL010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5421
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.209"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..375)
                     /locus_tag="RHX21_004571"
     CDS             complement(<1..375)
                     /locus_tag="RHX21_004571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708769.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HDV1989648.1"
                     /translation="MKTLSQNTTSSACAPETDLQKLVATPVPDERRISFWPQHFGLIP
                     QWVTLEPRIFGWMDRLCEDYCGGIWNLYTLNNGGAFMAPEPDDDDDETWVLFNAMNGN
                     RAEMSPEAAGIAACLMTYSHHAC"
     gene            complement(717..1535)
                     /locus_tag="RHX21_004572"
     CDS             complement(717..1535)
                     /locus_tag="RHX21_004572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HDV1989649.1"
                     /translation="MRLASRFGYTNQIRRDRPLTHEELMHYVPSIFGEDRHTSRSKRY
                     AYIPTITVLESLQREGFQPFFACQTRVRDPGRRGYTKHMLRLRRAGEINGEHVPEIIL
                     LNSHDGTSSYQMLPGYFRFVCQNGCVCGQSPGEVRVPHRGNVVDRVIEGAYEVVGVFD
                     RIEEKRDAMQSLVLPPPTRQALAQAALTYRYGDEHQPVTTADILTPRRREDYGKDLWS
                     AYQTIQENMLKGGISGRSAKGKRIHTRAIHNIDTDIKLNRALWVMAETLLESLR"
     gene            complement(1690..1848)
                     /locus_tag="RHX21_004573"
     CDS             complement(1690..1848)
                     /locus_tag="RHX21_004573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001550547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF905 family protein"
                     /protein_id="HDV1989650.1"
                     /translation="MPGCTSRLLPEGPFSREQAVAVKTAYRNVFTEDDQGTYSRLVIR
                     NAEGQLRW"
     gene            complement(1919..4765)
                     /gene="ag43"
                     /locus_tag="RHX21_004574"
     CDS             complement(1919..4765)
                     /gene="ag43"
                     /locus_tag="RHX21_004574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin Ag43"
                     /protein_id="HDV1989651.1"
                     /translation="MKRHLNTSYRLVWNHITGTLVVASELARSRGKRTGVAVALSLAA
                     VTSLPALAADTVVQAGETVNGGTLENHDNQIVFGTANGMTISTGLEYGPDNEANTGGQ
                     WIQNGGIANNTTVTGGGLQRVNAGGSVSDTVISAGGGQSLQGQAVNTTLNGGEQWVHE
                     GGIATGTVINEKGWQAVKSGAVATDTVVNTGAEGGPDAENGDTGQFVRGNAARTTINK
                     NGRQIVAVEGTANTTVVYAGGDQTVHGHALDTTLNGGYQYVHNGGTASDTVVNSDGWQ
                     IVKEGGLADFTTVNQKGKLQVNAGGTATNVTLKQGGALVTSTAATVLGSNRLGNFTVE
                     NGKADGVVLESGGRLDVLEGHSAQKTRVDDGGTLAVSAGGKATGVTMTSGGALIADSG
                     ATVEGTNASGKFSIDGISGQASGLLLENGGSFTVNAGGQASNTTVGHRGTLMLAAGGS
                     LSGRTQLSKGASMVLNGDVVSTGDIVNAGEIYFDNQTTPDAVLSRAVAKGNAPVTFHK
                     LTTSNLTGQGGTINMRVRLDGSNASDQLVINGGQATGKTWLAFTNVGNSNLGVATTGQ
                     GIRVVDAQNGATTEEGAFALSRPLQAGAFNYTLNRDSDEDWYLRSENAYRAEVPLYTS
                     MLTQAMDYDRILAGSRSHQTGVNGENNSVRLSIQGGHLGHDNNGGIARGATPESSGSY
                     GFVRLEGDLLRTEVAGMSLTTGVYGAAGHSSVDVKDDDGSRAGTVRDDAGSLGGYLNL
                     THTSSGLWADIVAQGTRHSMKASSDNNDFRARGWGWLGSLETGLPFSITDNLMLEPQL
                     QYTWQGLSLDDGQDNAGYVKFGHGSAQHVRAGFRLGSHNDMSFGEGTSSRDTLRDSAK
                     HRVRELPVNWWVQPSVIRTFSSRGDMSMGTAAAGSNMTFSPSRNGTSLDLQAGLEARV
                     RENITLGVQGGYAHSVSGSSAEGYNGQATLNVTF"
     gene            complement(5137..>5421)
                     /locus_tag="RHX21_004575"
     CDS             complement(5137..>5421)
                     /locus_tag="RHX21_004575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase family protein"
                     /protein_id="HDV1989652.1"
                     /translation="AVSACTGWELDTLVSALMTALPDHAASPLMTRLQDELRTESVRS
                     QAREQFTGAVDRIFDTAESVCIASVARAVLRAVRDSVVSVARAVWNWIFF"
BASE COUNT         1157 a         1565 c         1445 g         1254 t
ORIGIN      
        1 acaggcatga tgactgtacg tcatcagaca ggcagcaatg ccggcggctt ccgggctcat
       61 ttcagcgcgg ttaccgttca tggcattgaa cagtacccat gtttcgtcat catcgtcatc
      121 cggttcgggt gccataaatg ccccgccgtt gttcagggtg tacagattcc agataccacc
      181 gcagtagtct tcacacagac ggtccatcca gccgaagata cggggctcca gggtcaccca
      241 ctgtggaatg aggccaaagt gctgcggcca gaagctgatg cgccgttcat cagggacggg
      301 agtggctacc agtttttgca ggtcagtctc cggtgcacag gccgaagagg tggtgttctg
      361 agacaatgtt ttcatgtatg aaatccttgt aatgtgaata aatgagaggg agtaaaggtc
      421 gggagctggc aacatcacgt tcatcactga ccgtgatgac ccggtaatat cagggatgaa
      481 tgatattcgg ctgaaattcc ggacagccgt acgcgtaacc gttccggtca cagacggatg
      541 gccagatgcc attgcctgta tactcagtct gcacagactg atttctccgg gacggtaaag
      601 cagacgggta caccaggcgc acaggtcatc atcagaaatg gaacgacacc ccggcagcgc
      661 ctccggggcg tcgggtgatt ctggtgcctg aatcacgcct tcagggacat gctgcatcag
      721 cgcaggctct ccagcagcgt ttctgccatt acccacaatg cgcggttgag cttaatatcg
      781 gtgtcgatgt tgtgaatggc acgggtgtgg atacgttttc cttttgcact gcggccggaa
      841 attccgcctt tcagcatatt ctcctggatg gtctgatatg cgctccacag gtctttaccg
      901 taatcctccc ggcgtcgtgg tgtcagaatg tcagcggtgg tgactggctg atgttcgtca
      961 ccataacggt aagtcagtgc cgcctgtgcc agcgcctggc gtgtcggtgg cggcaggacc
     1021 agcgactgca tggcatcacg cttttcctca atccggtcaa acacgcccac cacctcgtaa
     1081 gccccttcaa tgactctgtc caccacattt ccccgatgcg gaacacgcac ttcccccgga
     1141 gactgaccac agacgcatcc gttctgacag acgaacctga agtaacccgg cagcatctgg
     1201 tagctggagg taccgtcatg ggagttgagc agaatgattt cagggacatg ttctccgttt
     1261 atctctccgg cccgccgcag acgcagcatg tgttttgtgt atccccggcg gcccgggtcg
     1321 cgcacacggg tctggcaggc gaagaatggc tgaaagcctt cccgctgcag gctttccagt
     1381 acggtgatgg tgggaatgta cgcatatcgt ttactgcggg aagtatgccg gtcttcaccg
     1441 aaaatactgg gaacatagtg catcagttct tcgtgtgtca gcggacggtc acggcgtatc
     1501 tggttcgtat aaccaaaacg actggctagt cgcataattt gctccttatc ggtggttaag
     1561 atttactggt gtaataaatg aaaaagccac gtctcccgga gaagacgcgg cctgacagat
     1621 gaaatgaatg acgtttattg tctgagaagc ccttaactgg cgagctgagt attaagctgt
     1681 gttccggcat caccagcgca actgaccttc agcattacgg ataaccagcc gggaatatgt
     1741 tccctggtca tcttcagtaa acacattgcg gtaagctgtt ttgacggcaa cagcctgttc
     1801 gcgtgagaaa gggccttcgg gcaataaacg tgatgtacaa cccggcatat ctgttgctcc
     1861 ctgaaagtaa aaagccccgg tcatgatgac cggggcctga aggagagtga cctgattatc
     1921 agaaagtcac attcagcgtg gcctgaccgt tataaccttc agcgctgctg ccgctgacgc
     1981 tgtgggcata accgccctga acgcccaggg tgatattttc ccggacacgg gcttccagtc
     2041 cggcctgcag gtccagtgac gtgccattcc gggacggtga gaacgtcatg ttactgccgg
     2101 cggcggctgt acccatgctc atgtcacccc gggagctgaa ggtgcggata acagaaggct
     2161 gtacccacca gttcaccggc agttcacgca cacggtgttt tgcactgtcg cgcagggtgt
     2221 cacgggatga ggtgccttca ccaaagctca tatcgttgtg gctgcccaga cggaaaccgg
     2281 cacgcacatg ttgtgcactg ccatgcccaa acttcacata accggcgtta tcctggccgt
     2341 catccaggga aagtccctgc caggtatact gcagttgtgg ctccagcatc aggttgtcag
     2401 tgatactgaa gggcagaccg gtttccagtg agcccagcca gccccagccc cgggcgcgga
     2461 agtcgttatt gtccgatgac gctttcatgc tgtggcgggt tccctgtgcc acaatgtcag
     2521 cccacaggcc ggaggacgtg tgtgtcagat tcaggtatcc gcccaggctg ccggcatcat
     2581 cccggaccgt gccggcgcgg gaaccgtcat catccttaac atcaacggaa gaatggcctg
     2641 cggcaccata cacccctgtc gtcagagaca taccggcaac ctctgttctc agcaggtcac
     2701 cctccagacg gacgaagcca tagctgccgc tgctttccgg cgtggctcca cgggcaatac
     2761 cgccgttgtt atcgtgaccg agatgaccgc cctgaatgct gagacggacg ctgttatttt
     2821 caccgtttac accggtctga tggctgcggg agcctgccag aatccggtca tagtccattg
     2881 cctgtgtcag catggatgta tacaggggga cttcagcacg ataagcattt tcactgcgca
     2941 ggtaccagtc ttcatcgctg tcacggttca gggtgtagtt aaaggcgccg gcctgaagcg
     3001 ggcgactcag ggcaaacgca ccttcttctg tggtagcgcc attctgtgca tccacaaccc
     3061 ggataccctg tccggtggtt gccaccccga ggttactgtt tccgacattt gtaaacgcaa
     3121 gccaggtttt gccggttgcc tgaccaccat taatcaccag ctggtcagag gcattgctgc
     3181 catcaaggcg aacacgcata ttgatagtgc caccctgacc ggtgaggtta ctggttgtca
     3241 gtttatggaa cgttaccggg gcgttgcctt ttgcaacagc acggctcagt acggcatccg
     3301 gtgttgtctg attgtcaaag taaatctccc ctgcgttaac aatatcgccg gtactgacca
     3361 catcaccatt cagtaccatg ctggcgcctt tactgagctg tgttctgcca ctcagacttc
     3421 ccccggcagc cagcatcagt gttccacgat gtccgacagt ggtgttgctg gcctgtcccc
     3481 cggcattaac cgtaaagctg ccgccatttt ccagcagcag gccgctggcc tgaccggata
     3541 tgccatcaat actgaactta ccgctggcat tggtcccctc aacagtggca ccactgtctg
     3601 caatcagggc accaccggat gtcatggtga cacctgttgc cttaccaccg gcagacactg
     3661 ccagggttcc gccgtcatcc acccgtgttt tctgcgctga atggccttcc agtacatcca
     3721 ggcgaccgcc ggactccaga acaacgccgt cagccttacc gttttccacc gtgaaattgc
     3781 ccagacggtt gctgccaaga accgttgccg cagtactggt gaccagtgct ccaccctgtt
     3841 tcagggtgac attcgtggct gtaccaccgg cgttcacctg cagtttgcct ttctggttaa
     3901 cggtggtgaa atccgccaga ccaccttcct tgacaatctg ccagccgtca ctgtttacaa
     3961 ccgtgtcaga ggctgtgcct ccgttgtgca catactggta accgccattc agtgtggtat
     4021 ccagcgcatg cccgtgtacc gtctggtcgc cgccggcata aaccacagtg gtatttgctg
     4081 ttccttcaac agccacaatc tgacgaccat ttttattgat ggtggtacgt gcggcatttc
     4141 cgcgaacaaa ctgcccggta tcaccatttt ctgcatccgg ccccccttcc gcgccggtat
     4201 tcacaaccgt gtcggttgcc actgcgccgg atttgacggc ctgccagccc ttctcattaa
     4261 tgacggtacc cgttgcaatc ccgccttcat gtacccactg ctcaccgccg ttcagagtgg
     4321 tattcactgc ctgcccctga aggctctgtc cgcctccggc actgataacc gtgtctgaaa
     4381 cgcttcctcc ggcattcact ctctgaagac caccaccggt gacagtagtg ttgttggcga
     4441 taccgccatt ttgtatccat tgtccgccgg tattggcctc gttatccggc ccatactcca
     4501 gaccggtact gatggtcatt ccgttggccg taccgaagac aatctggttg tcatgatttt
     4561 ccagtgttcc accgttcacg gtttctcccg cctggacaac cgtgtcagca gccagtgccg
     4621 ggagtgacgt gacagcagca agagacagag caactgccac accggtgcgt tttccccgtg
     4681 agcgcgccag ttcggaagcc accaccaggg tgcccgtaat gtgattccat accagcctgt
     4741 agctggtgtt cagatgtcgt ttcatcagct tttccttaca gagggtgaat aaaaaagccg
     4801 gtacccacaa atgtggatac cggcaggtac aaaacagcat ggtcagataa agtggttttt
     4861 cccggacata aatgcttccc ctctctcatc cgccagagaa gtatcagtcc gttgtgtgca
     4921 attccgttct gcatgatgaa gagattcagc tgccttttcg caggccatta accactataa
     4981 acgatcgata tcagcgatcg atacctgttt tatcgatcgt tttattctat taacagcaag
     5041 gcagtcacgc aagagaaaga ggtgggtctg aggtgtttgt gtcatgtttt cagttggtta
     5101 acgcaatgta atcaggcatt tcccctggca gagtgttcag aagaaaatcc agttccatac
     5161 agcgcgggca acagagacca ccgagtcacg gacggcacgc agaaccgcgc gtgcaacaga
     5221 ggcaatacag acgctctccg cagtgtcaaa tatccggtcc accgcaccgg taaactgttc
     5281 acgggcctga gaccggacag attccgtgcg cagctcgtcc tgcaggcggg tcatcagggg
     5341 actggcggca tggtcgggaa gcgctgtcat gagcgcactg accagcgtat ccagttccca
     5401 gccggtgcag gccgatacgg c
//
LOCUS       DAPGUL010000206         5402 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.210, whole genome shotgun sequence.
ACCESSION   DAPGUL010000206 DAPGUL010000000
VERSION     DAPGUL010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5402)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5402)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5402
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.210"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            115..1473
                     /gene="mltD"
                     /locus_tag="RHX21_004576"
     CDS             115..1473
                     /gene="mltD"
                     /locus_tag="RHX21_004576"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase D"
                     /protein_id="HDV1989653.1"
                     /translation="MKAKAILLASVLLVGCQSTGNVQQHAQSLSAAGQGEAAKFTSQA
                     RWMDDGTSIAPDGDLWAFIGDELKMGIPENDRIREQKQKYLRNKSYLHDVTLRAEPYM
                     YWIAGQVKKRNMPMELVLLPIVESAFDPHATSGANAAGIWQIIPSTGRNYGLKQTRNY
                     DARRDVVASTTAALNMMQRLNKMFDGDWLLTVAAYNSGEGRVMKAIKTNKARGKSTDF
                     WSLPLPQETKQYVPKMLALSDILKNSKRYGVRLPTTDESRALARVHLSSPVEMAKVAD
                     MAGISVSKLKTFNAGVKGSTLGASGPQYVMVPKKHADQLRESLASGEIAAVQSTLVAD
                     NTPLNSRVYTVRSGDTLSSIASRLGVSTKDLQQWNKLRGSKLKPGQSLTIGAGSSAQR
                     LANNSDSITYRVRKGDSLSSIAKRHGVNIKDVMRWNSDTANLQPGDKLTLFVKNNNMP
                     DS"
     gene            complement(1521..2291)
                     /locus_tag="RHX21_004577"
     CDS             complement(1521..2291)
                     /locus_tag="RHX21_004577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDV1989654.1"
                     /translation="MTTQSHHDHVEKQFSSQACEYLTSTVHASGRDLQRLAVRLADYP
                     GASVLDMGCGAGHASFVAAQNVSTVVAYDLSAHMLDVVAQAAEVRQLKNITTRQGYAE
                     SLPFADNAFDIVISRYSAHHWHDVGAALREVNRILKPGGRMIVMDVMSPGHPVRDIWL
                     QTVEALRDTSHVRNYASGEWLRLINEANLIVDNLITDKLPLEFSSWVARMRTPEALVD
                     AIRIYQQSASTEVRTYFALQNDGSFTSDIIMVEAHKAA"
     gene            complement(2369..3169)
                     /locus_tag="RHX21_004578"
     CDS             complement(2369..3169)
                     /locus_tag="RHX21_004578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HDV1989655.1"
                     /translation="MRKNTYAMRYVAGQPAERILPPGSFASIGQALPPGEPLSTEERI
                     RILVWNIYKQQRAEWLSVLKNYGKDAHLVLLQEAQTTPELVQFATANYLAADQVPAFV
                     LPQHPSGVMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNIHAVNF
                     SLGVDVYSKQLLPIGDQIAHHSGPVIMAGDFNAWSRRRMNALYRFAREMSLRQVRFTD
                     DQRRRAFGRPLDFVFYRGLNVSEASVLVTRASDHNPLLVEFSPGKPDK"
     gene            3410..4324
                     /locus_tag="RHX21_004579"
     CDS             3410..4324
                     /locus_tag="RHX21_004579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV1989656.1"
                     /translation="MKATSEELAIFVSVVESGSFSRAAEQLGQANSAVSRAVKKLEMK
                     LGVSLLNRTTRQLSLTEEGQRYFRRVQSILQEMAAAESEIMETRNTPRGLLRIDAATP
                     VVLHFLMPLIKPFRERYPEVTLSLVSSETIINLIERKVDVAIRAGTLTDSSLRARPLF
                     NSYRKIIASPDYISRYGKPETIDDLKQHICLGFTEPASLNTWPIARSDGQLHEVKYGL
                     SSNSGETLKQLCLSGNGIACLSDYMIDKEIARGELVELMADKVLPVEMPFSAVYYSDR
                     AVSTRIRAFIDFLSEHVKTAPGGAVREA"
     gene            complement(4321..5124)
                     /gene="dkgB"
                     /locus_tag="RHX21_004580"
     CDS             complement(4321..5124)
                     /gene="dkgB"
                     /locus_tag="RHX21_004580"
                     /EC_number="1.1.1.346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-didehydrogluconate reductase DkgB"
                     /protein_id="HDV1989657.1"
                     /translation="MAIPAFGLGTFRLKDDVVISSVITALELGYRAIDTAQIYDNEAA
                     VGQAIAESGVPRHELYITTKIWIENLSKDKLIPSLKESLQKLRTDYVDLTLIHWPSPN
                     DEVSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQ
                     NRKVVAWAKQHGIHITSYMTLAYGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSV
                     IPSSTKRKNLESNLKAQNLQLDAEDKKAIAALDCNDRLVSPEGLAPEWD"
     gene            complement(5287..5363)
                     /locus_tag="RHX21_004581"
     tRNA            complement(5287..5363)
                     /locus_tag="RHX21_004581"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(5327..5329),aa:Asp,seq:gtc)
BASE COUNT         1416 a         1310 c         1343 g         1333 t
ORIGIN      
        1 agagcgtttt gcatggttaa ggtcaaagaa agataggttc tgataaaact ttcttgtcat
       61 cggctccgtt cgccgttatg atcggtcgtc ttttaagcaa ctattgacac acacatgaag
      121 gcaaaagcga tattactcgc ctctgtcctg ctcgtgggtt gccagagtac cggcaacgtt
      181 caacagcacg cacagagcct ttctgcagct ggtcaagggg aagcagcaaa gtttacaagt
      241 caggcacgat ggatggacga tgggacgtct atcgcgccag atggtgactt gtgggctttc
      301 attggcgacg agctaaagat gggaattccg gaaaatgacc ggattcgcga acagaaacag
      361 aaatatttac gcaataagag ctatctccac gatgtaactt tacgggcaga gccgtatatg
      421 tactggatag cagggcaagt taaaaaacgt aacatgccta tggaactggt actactaccc
      481 atagtggaga gcgcttttga tcctcacgca acgtctggcg ccaatgccgc aggcatctgg
      541 cagatcattc cgagcacggg gcgcaattat ggtttgaaac agacccgcaa ttatgacgcg
      601 cgtcgcgatg ttgttgcttc aacaactgcc gcgctgaata tgatgcagcg tctgaacaaa
      661 atgtttgacg gcgactggct tctgaccgta gcggcttata acagcggcga aggtcgggtc
      721 atgaaggcaa ttaaaacgaa caaagcgcgt gggaaatcca cggacttctg gtcgttaccg
      781 ttgccgcagg aaacgaagca gtacgtgcct aaaatgctgg cattgagtga tattctcaaa
      841 aacagcaagc gttatggcgt acgtctgcca acgaccgatg aaagccgtgc tctggcgcgt
      901 gtgcacctga gcagcccggt tgaaatggcg aaggttgcag atatggcggg gatttccgtc
      961 agcaagctga agacattcaa cgctggcgtg aaaggctcca cgctgggcgc aagtggtccg
     1021 caatacgtga tggtgccaaa gaagcatgca gatcaactgc gtgaatctct cgcttcaggc
     1081 gaaattgctg ctgtacagtc gacgctggtt gccgacaata cgccgcttaa cagccgtgtt
     1141 tacaccgtac gctctggcga cacgctttca agtatcgctt cacgtctcgg cgtaagcacc
     1201 aaagatttgc agcagtggaa caaactgcgc ggatctaagc tgaagccagg ccaaagtttg
     1261 acgattggtg caggcagtag cgcacagcga ctggcaaaca acagcgatag cattacgtat
     1321 cgtgtgcgca aaggcgattc gctttcaagc attgctaaac gccacggcgt gaacatcaaa
     1381 gatgtgatgc gctggaacag cgacactgcg aatctgcaac caggcgacaa gctgacgttg
     1441 tttgtgaaaa acaacaacat gccagattcc tgacaaacca gataataaaa aggcaccgat
     1501 tcccccggtg ccttttttat ttatgctgct ttatgtgctt ctaccatgat gatatcactg
     1561 gtgaaagagc catcattctg caaggcaaaa tacgttctca cctctgtcga tgcgctctgt
     1621 tggtaaatgc gaatagcgtc tactaacgct tctggcgtac gcattctcgc gacccatgaa
     1681 gaaaattcca gcggtaactt atctgtaatt aaattatcaa ctatcagatt ggcttcattg
     1741 attaacctca accactcacc gctggcgtag tttcgtacgt gagaggtatc gcgtaatgct
     1801 tctaccgtct gtaaccagat gtcgcgcact ggatgacccg gagacattac gtccatcaca
     1861 atcatcctac cgccaggttt caatatccgg ttcacttcac gcagtgctgc accaacatca
     1921 tgccagtgat gggcagaata acggctgata acaatatcaa atgcgttatc ggcaaatggc
     1981 agactttcgg cataaccctg gcgggtggtg atatttttca gttgccggac ttcggcagct
     2041 tgtgccacga catccagcat gtgggcagat aagtcatacg ccaccaccgt gctcacgttt
     2101 tgcgcagcga caaagctggc atgccctgct ccgcagccca tatcaagtac acttgcacca
     2161 ggataatcag ccagacgcac cgccaggcgc tgtaaatctc gtccggatgc atgtacggta
     2221 ctggtcagat attcgcaggc ttgagagcta aactgctttt ctacgtggtc atggtgggat
     2281 tgtgttgtca ttgcgctgtc cttttgttgt ttgagtataa aaggacagcg ccaaacgttg
     2341 gtctgccctg tggcagacct gacatacctt atttatcagg cttgccggga ctgaattcaa
     2401 cgagtagcgg attgtgatcg gaagcgcgcg taaccaatac agaagcttcg ctgacgttca
     2461 gaccacggta gaaaacaaaa tcgagcgggc ggccaaacgc ccgacggcgc tgatcatcgg
     2521 taaaacgcac ctggcgcagc gacatttccc gcgcaaagcg atataacgcg ttcatccttc
     2581 tacggctcca ggcattgaaa tctcccgcca taatgaccgg gccgctgtgg tgagctatct
     2641 gatcaccaat aggaagtaac tgcttactat agacatccac gcccagactg aagttgacgg
     2701 cgtgtatatt aaccaccatc aacaggcggg tgtcaggtaa tggatagacc gtcaccagtg
     2761 ccgacttcgc cagacgcaaa atgggttctc gttcacgtaa cgggcagcaa tacactggat
     2821 gcgccgccga aagggtcatt acaccggaag gatgttgtgg cagcacgaaa gcgggcacct
     2881 gatcggcggc aagatagtta gcggtcgcaa actgtactaa ctctggcgtt gtctgcgctt
     2941 cctgcaataa caccagatgt gcatctttgc cgtagttctt taataccgac aaccattcag
     3001 cgcgttgctg tttgtatatg ttccacacca ggatccgaat acgctcttcg gtacttaacg
     3061 gttctccagg tggtaatgcc tggccgatgc tcgcaaaaga ccccggcggt aagatccttt
     3121 ccgcaggttg tccggcaaca tagcgcatgg cataggtgtt ttttcgcact tttgactttg
     3181 aaacctctat tacgtcaacc cttccgcact cgggagggtt ctactgttat agggatttta
     3241 gctcactctt tcaacgagca attgtatatt gttatgtaag caagtgctta cacaggtcag
     3301 aattttgctc attattgaga acattaaatc ggatgacata tcacgcatcc tgatggttta
     3361 atgacaaata aattcaaaat atctcttcta ttttgcaaca ggagcaaaaa tgaaagccac
     3421 gtcggaagaa ctcgccattt ttgtttcggt cgtagaaagc ggcagcttta gccgggcagc
     3481 ggaacaatta gggcaagcaa actcagcggt aagccgggca gtgaaaaagc tggagatgaa
     3541 acttggcgtt agcctgctta atcggaccac gcgacaactt agcctgacgg aagaaggcca
     3601 gcgttatttt cgtcgcgtac agtcaatttt gcaggagatg gcagcggcag aatcagaaat
     3661 tatggagacg cgtaatacac cgcgtggact gttgcgcatc gatgccgcaa ctccagtggt
     3721 gctgcacttt ctgatgccgt tgattaagcc tttccgtgaa cgctatccgg aagtcacttt
     3781 atcgctagtc tcctccgaaa cgattattaa tttgatcgaa agaaaagtgg atgtcgcgat
     3841 acgcgctggt acgttaacgg attccagctt acgtgccagg ccgttattta acagttatcg
     3901 aaaaattatc gcctcccccg attatatttc ccgctacggg aagccagaaa cgatcgacga
     3961 tttaaagcaa catatttgcc tgggattcac tgaacccgct tccctcaata cctggccgat
     4021 agcccgtagc gatggacaat tacatgaggt gaagtacggt ttgtcatcca atagtgggga
     4081 aacactgaaa cagctttgcc tgagtggcaa cgggattgcg tgtttgtccg actacatgat
     4141 cgacaaagaa atcgctcgcg gagaattggt ggagttaatg gcagataaag tgttgccagt
     4201 ggaaatgcca ttcagtgccg tctattacag cgaccgtgcg gtaagtacgc gcatccgggc
     4261 ttttatcgat ttccttagcg agcatgtaaa aacagctccc ggaggagctg tcagagaggc
     4321 ttaatcccat tcaggagcca gaccttccgg gctaaccagg cggtcgttgc aatccagtgc
     4381 ggcgatcgct tttttatctt cggcatcaag ctgtaaattt tgtgccttaa gattactttc
     4441 caggttttta cgtttagtag aagaaggaat tactgagtaa ccttccccca tagcccacgc
     4501 cagaatcact tgtgccggag tcgcattgtg tttagctgcg atacgagcaa taacctcatc
     4561 tttcagggcc ttaccatacg ccagcgtcat ataggaagta atatggatgc cgtgctgttt
     4621 agcccaggca accactttac ggttttgcag ataaggagag agttcaatct ggttagtagc
     4681 gatgttttca gcaccaacag cagcaatcgc tttttccatc aacgggatcg tgaagttgga
     4741 aataccgatc tcacgcgtca gcccttgttt tttggcttcc agcagcgcct gcataaactc
     4801 ttcaacagag acttcatcgt ttggtgacgg ccagtggatt agcgtcagat caacataatc
     4861 ggtacgcaat ttttgcaggc tctctttcag acttgggatc aatttgtctt tgctgagatt
     4921 ttcaatccag attttagtgg tgatgtagag ttcatgacgt ggcacgccac tttctgcaat
     4981 cgcctgacct actgcggctt cgttatcata gatttgtgcg gtatcaattg cgcgataacc
     5041 aagttcaagc gccgttatca cagatgaaat aacaacgtcg tctttcagac ggaaagtacc
     5101 taaaccaaat gcagggatag ccataatatg cctcttttaa tgctattttc gttaactgag
     5161 gtgattatgg gcttcagact gttgaggaaa aagagcgtaa aatgcagagg atttttgcga
     5221 ttctggcaat aatagatata cagacgaaaa aaaacctcga gcgttaactc gaggcttctt
     5281 aataagtggc ggaacggacg ggactcgaac ccgcgacccc ctgcgtgaca ggcaggtatt
     5341 ctaaccgact gaactaccgc tccaccgaat tcttttacaa ccaccggttt tatgaccggc
     5401 tt
//
LOCUS       DAPGUL010000207         5368 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.211, whole genome shotgun sequence.
ACCESSION   DAPGUL010000207 DAPGUL010000000
VERSION     DAPGUL010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5368
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.211"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            37..1365
                     /locus_tag="RHX21_004582"
     CDS             37..1365
                     /locus_tag="RHX21_004582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA circularization N-terminal domain-containing
                     protein"
                     /protein_id="HDV1989658.1"
                     /translation="MTWKDRLQDASFRSVPFKVEEESAGTGRRVETHEYPNRDKPYTE
                     DLGKITFRPSITAYVVGDDCFDQRDRLIEALNKPGPGTLVHPTYGELKVCVDGEVRVS
                     TSKSEGRIVRFDLKFVEAGELSYPTSGVATAQTLMSSCSALDDCISDSFSGFSIDGVA
                     DFVQNDVIGNASTMLGYVSDAMKVVDSAVSDAARLLQGDISVLMPPPSSGKNFVEQVQ
                     KMWRTGKRLYGNASDLVTMIKTLSGVSLGSDLQPRGVWKTDSKTTATATQQRNMVAST
                     LRTTAISEAAYAVTRLPAPTTSAVMQNAAVGQSTTPAQSSGWPAVTHPVLNNAPAVKN
                     TVDLPTWEELTDIRDTLNTAIDKELSRTTSDALFLALRRVKADLNADINTRLEQSARI
                     IQRTPDEVLPALVLAATWFDNAARDADIIRRNAITHPGFVPVIPLKVPVQ"
     gene            1362..2441
                     /locus_tag="RHX21_004583"
     CDS             1362..2441
                     /locus_tag="RHX21_004583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate protein"
                     /protein_id="HDV1989659.1"
                     /translation="MNDNVTLRVNGREWNGWTSVRIGAGIERLARDFSVEITRQWPGD
                     EGITTLQPRIKNGSKVEVLISDELVITGWVEATPVRYDARSVSTGIAGRSLTADLIDC
                     AAEPTQFNGRSLVQIAQALAAPFGIEVVNNGAPSGVIPDVQPDHGETVIEVINKILGQ
                     QQALAYDDPHGRLVIGGIGSTRAHTALVLGENILSCDTEKSIRERFSVYQVAGQRAGN
                     DDDFGEATTTALRARTEDAFISRYRPMYIRQTGQATGAGCIARADFEARQRAARTDET
                     TYVVQGWRQGNGTLWQPNQRVIVFDPVCGFDNTELLVSEVTFTLDQNGTLTEIRVGPP
                     DAYLPEPEAPGARKKKKARVQEDPF"
     gene            2441..2989
                     /locus_tag="RHX21_004584"
     CDS             2441..2989
                     /locus_tag="RHX21_004584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015364403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein"
                     /protein_id="HDV1989660.1"
                     /translation="MSTIEAMQRQLLGLIGRAVVKSISAATKCQTVDVSLIAGEPKAG
                     VEHLEPYGFTARANSGAEAVVLFPDGDRSHAVVVTVSDRRYRLKGLQTGEVAVYDDQG
                     QSVTLTREGIVVDGAGKTITFCNSPKARFEMDLEVTGQVKDLCDSGGTTMSAMRLAYN
                     GHRHRENGQGSNTDKPDKAMEA"
     gene            2989..3414
                     /locus_tag="RHX21_004585"
     CDS             2989..3414
                     /locus_tag="RHX21_004585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage GP46 family protein"
                     /protein_id="HDV1989661.1"
                     /translation="MELWLTVNGKRTCASAPLDPLTRAVVISMFTWRRAEPDDNADVP
                     MGWWGDTWPAVQNDRYGSRLWLLQRSKLTNQLVQTVRGYIRECLQWMIDDGVVSRIDL
                     DIRRTGINELGNSITLWRRDGPVMISFDDLWSAITHGGQ"
     gene            3401..4459
                     /locus_tag="RHX21_004586"
     CDS             3401..4459
                     /locus_tag="RHX21_004586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001536648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HDV1989662.1"
                     /translation="MADSEFQRPTLAENISMLRNDLFARLDVSDTLRRMDEDVRAKVY
                     AAALHTVYGYIDYLAMNMLPDLCDESWLARHAAMKRCPRKGATAASGYMRWEGVSDGL
                     KVTAGSVIQRDDLVQYTATADATSTGGVLRVPIACSSAGAVGNADDGTSLILVTPVNG
                     LPSSGEADTLTGGFDTEELETWRARVIERYYWTPQGGADGDYVVWAKEVPGITRAWTY
                     RHWMGTGTVGVMIASSDLINPIPEESTETAARQHIEPLAPVAGSDLYVFRPVAHKVDF
                     HIRVTPDTPEIRAAITAELRSFLLRDGYPQGELKVSRISEAISGANGEYSHQLLAPAD
                     NISIAKNELAVLGTISWT"
     gene            4450..5034
                     /locus_tag="RHX21_004587"
     CDS             4450..5034
                     /locus_tag="RHX21_004587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmfQ family protein"
                     /protein_id="HDV1989663.1"
                     /translation="MDVTNDDYIRLLSALLPPGPAWSASDPAIAGAAPSLTRAHQRAD
                     ALMRELDPRTTTELINRWERLCGLPDECIPAGTQTLRQRQQRLDAKVNLAGGINEDFY
                     LAQLAALGRPDATITRYDKSTFTCSSACTDAVNAPEWRYYWQVNMPAATNTTWMTCGD
                     PCDSALRIWGDTVIECVLNKLCPSHTYVIFKYPE"
     gene            5038..>5368
                     /locus_tag="RHX21_004588"
     CDS             5038..>5368
                     /locus_tag="RHX21_004588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase"
                     /protein_id="HDV1989664.1"
                     /translation="MHRIDTKTAQKDKFGAGKNGFTRGNPQTGTPATDLDDDYFDMLQ
                     EELCSVVEASGASLEKGRHDQLLTALRALLLSRKNPFGDIKSDGTVKTALQNLGLGDT
                     SGYVGRRL"
BASE COUNT         1196 a         1392 c         1662 g         1118 t
ORIGIN      
        1 gtaaatatta ctactgataa taaatatggg acttatatga cgtggaaaga caggcttcag
       61 gatgcgtcat ttcgcagcgt gccgtttaag gttgaagaag aaagtgcggg aaccggtcgt
      121 cgtgtggaaa cacatgaata cccgaaccgc gacaaaccct ataccgaaga cctggggaaa
      181 atcactttcc gcccgtccat cacggcttat gtggtgggag atgactgctt tgaccagcgt
      241 gatcgcctga ttgaagcgct gaataaaccc ggtcccggca cgcttgtcca tccgacatac
      301 ggtgagttga aagtctgtgt tgacggggaa gttcgggtca gcacatcgaa gagtgaaggg
      361 cgtattgtcc gctttgacct gaagtttgtc gaagcgggag aactctctta ccccacatca
      421 ggcgtggcga cggcgcagac gctgatgtca tcctgttctg cactggatga ctgcatcagt
      481 gacagcttca gcggtttcag tatcgatggc gtggcggatt ttgtgcagaa cgacgttatc
      541 ggtaatgcca gcacaatgct tgggtatgtt tctgatgcga tgaaagtggt ggattctgct
      601 gtatcggatg ccgccaggct gttgcagggg gatatctcgg tacttatgcc gccgccatcg
      661 tcaggaaaaa atttcgttga gcaggtgcag aaaatgtggc gtaccggaaa acgcctttat
      721 ggtaacgcca gcgacctggt caccatgatc aaaacgcttt ctggtgtcag cctcggcagc
      781 gatttgcaac cgcgcggcgt ctggaaaacg gacagtaaaa ccaccgccac agcgacgcag
      841 cagcgtaaca tggttgccag cacccttcgt acgactgcaa tcagcgaagc ggcgtatgcc
      901 gttacccgat tgcctgcgcc aacaacttct gcggtgatgc agaatgccgc agtggggcag
      961 tcaacaacac ccgcgcagag ctccggctgg cctgccgtca cgcatccggt gctgaacaat
     1021 gcaccggcgg tgaaaaacac ggttgacctg ccaacgtggg aagaactgac cgacattcgc
     1081 gacacactga atacggcaat tgataaggag ttgtcccgta caaccagtga tgcgctgttt
     1141 ctggcgctgc gccgggtgaa agcagatctg aatgcggata tcaacacgcg ccttgaacag
     1201 tctgctcgga tcattcagcg cacgccggat gaggttttac ccgcgctggt gctggcggcg
     1261 acctggtttg ataacgcggc gcgtgacgcg gacattatcc ggcgtaatgc cattacgcat
     1321 cccggttttg tgccggtgat ccctctgaag gtgccagtgc aatgaacgac aatgtcacgc
     1381 tacgggtaaa tggccgggag tggaatggct ggacatcggt gcgcatcggt gccggtattg
     1441 aacggctggc acgggatttc agtgtggaga tcacccgcca gtggccggga gatgagggta
     1501 tcaccacgct tcagccgcgt attaaaaacg gttcaaaagt ggaagttctg attagtgatg
     1561 aactggtgat caccggctgg gtggaggcga cgcccgttcg ttacgatgcc cgttcggtca
     1621 gcaccggtat tgccggacgc agtctgaccg ctgacctgat tgactgtgca gccgaaccga
     1681 cacagtttaa cggacgatcg ctggtacaga ttgcgcaggc gcttgctgcg cctttcggca
     1741 ttgaggtggt gaacaacggt gcgccgtcgg gcgttattcc tgatgtccag cctgatcacg
     1801 gcgaaacggt gattgaggtg atcaacaaaa tactcggtca gcagcaggca ctggcttacg
     1861 acgacccgca cggcaggctg gtgattggcg gtattggctc aacgcgggca cataccgcgc
     1921 ttgtactcgg ggaaaacatc ctttcctgcg atacggagaa gagtatccgg gagcggtttt
     1981 ctgtttacca ggtggcgggg cagcgtgccg gaaacgacga tgatttcggt gaggccacca
     2041 ccaccgcgct gcgggcccgc acagaggacg catttatttc ccgttaccgt ccgatgtata
     2101 tcaggcagac agggcaggcc acgggggcag gctgtattgc ccgtgctgac tttgaagccc
     2161 gacaacgggc ggcgcggacg gatgaaacca cctatgtggt gcagggctgg cgacagggta
     2221 acggtacgct gtggcagccc aaccagcggg tgattgtctt cgatccggtc tgtggtttcg
     2281 acaataccga actgcttgtc tcggaagtca cgtttactct ggaccagaac ggcaccctga
     2341 cggaaatccg tgtcggccca cctgatgctt atctgcctga acccgaagcc cccggcgcgc
     2401 ggaaaaagaa aaaagccaga gtacaggagg acccgttctg atgagtacga ttgaagccat
     2461 gcagcgacaa ctcctcggcc tgattgggcg ggccgtggtg aaaagcatca gtgccgccac
     2521 gaaatgtcag accgtggatg tgtccctgat tgccggtgaa cccaaagccg gggttgaaca
     2581 tcttgaaccc tacggtttta ccgcaagggc aaacagcggt gcggaagcgg tggtgttgtt
     2641 tccggatggc gaccgttctc atgcggtggt tgttacggtg tcggaccggc gctaccgcct
     2701 gaaagggctg cagacgggtg aggtggctgt ctatgacgat caggggcagt ccgtgacact
     2761 gacccgggag gggatcgtgg tggacggtgc aggtaaaacg atcacgtttt gcaattcacc
     2821 taaagcacgt tttgaaatgg accttgaagt gaccggacag gtgaaagacc tgtgcgactc
     2881 cggcggcacc accatgtcag cgatgcggct tgcctataac gggcatcgtc acagagagaa
     2941 cggtcagggc agtaacaccg acaaacctga taaagcgatg gaggcatgat ggaactgtgg
     3001 ctgacggtga acggtaaacg cacctgcgcc agcgcaccgc tggatccgct gacccgcgcc
     3061 gtggtgattt ccatgtttac ctggcggcgg gcggagcctg atgacaatgc cgacgtcccg
     3121 atgggatggt ggggggatac ctggcctgcg gtacagaatg accgttacgg ctcccgactg
     3181 tggctgcttc agcgcagcaa actgaccaat caactggtgc agacggtaag ggggtatatc
     3241 cgcgaatgcc tgcaatggat gattgatgac ggcgtggtgt cccgtattga tctggatatc
     3301 cgccgcaccg ggattaatga actgggtaac agtatcactc tctggcgtcg tgacggaccg
     3361 gtaatgattt cttttgatga tctgtggagt gcgataacgc atggcggaca gtgaatttca
     3421 gcgcccgacg ctggcagaaa atatcagtat gctccgtaac gatttattcg ccaggctgga
     3481 cgtcagcgac acgctccggc gcatggatga agacgtgcgg gcaaaggtgt atgcggcggc
     3541 gctgcatacg gtttacgggt acatcgatta tctggcaatg aacatgctgc ctgatctgtg
     3601 cgatgagtcc tggctggcgc gacatgctgc gatgaaacgg tgtccgcgca agggggccac
     3661 ggctgccagc gggtatatgc gctgggaagg tgtcagcgat ggcctgaagg tgaccgccgg
     3721 aagtgttatt cagcgcgatg acctggttca gtacacggca actgccgatg caaccagcac
     3781 cggtggtgtc ctgcgcgtgc cgatcgcctg ctcaagtgca ggcgcggtcg gtaacgctga
     3841 cgacggtacg tcattaattt tggtcacgcc ggttaatggt ctgccgtctt ccggcgaggc
     3901 agataccctg acaggtggat ttgatactga agagctggaa acgtggcgcg cccgcgtcat
     3961 tgagcggtat tactggacgc ctcagggcgg ggctgacggg gactatgtcg tctgggctaa
     4021 agaagtgccc ggcattaccc gcgcatggac ataccgacac tggatgggaa cggggactgt
     4081 cggtgtgatg attgccagca gtgacctgat taaccccatt ccggaagaat caacggaaac
     4141 ggcggcaaga caacatatcg agccactggc cccggtggca ggctctgatt tgtatgtatt
     4201 caggccggtg gcgcacaaag tggattttca tatccgcgtg acgccggaca caccggaaat
     4261 acgggctgcc atcaccgcgg agttgcgttc attcctgcta cgtgatggtt atccgcaggg
     4321 agagctgaag gtatcgcgta tcagtgaagc gatttccggt gcgaacgggg aatacagcca
     4381 tcagttgctt gctccggcgg acaatatctc cattgcaaaa aatgaactgg cggttctggg
     4441 gacgatttca tggacgtgac aaacgatgat tacatccgtc tgttgtcggc actgttgccc
     4501 cctggtccgg cgtggtcagc cagcgatccg gcgattgccg gtgcggcacc gtcattaacc
     4561 cgtgctcatc agcgtgcgga tgccctgatg cgggagctgg atccgcgcac caccaccgaa
     4621 ctgataaacc gctgggagcg tctgtgcggc ctgccggatg aatgtattcc ggcagggacg
     4681 cagacccttc gccagcgtca gcaacggctg gatgcgaagg ttaacctggc gggcggcatc
     4741 aatgaggatt tttaccttgc gcagcttgct gccctgggca gaccagatgc caccatcacg
     4801 cgatacgaca aaagcacgtt cacctgctca tcggcctgta ctgacgcggt gaatgcgccg
     4861 gaatggcggt attactggca ggtcaatatg ccagctgcca ccaacaccac ctggatgaca
     4921 tgtggcgatc cctgcgattc cgcactgcgt atctgggggg acaccgttat cgagtgcgtg
     4981 cttaacaaac tctgcccatc gcatacctac gtaattttta aatatccgga gtaatccatg
     5041 catcgtatag acacgaaaac cgcgcaaaag gataagttcg gcgcgggtaa gaacggtttt
     5101 acccgtggta acccccagac aggcacgcct gccaccgatc tggatgatga ctactttgac
     5161 atgttgcagg aagagctctg cagcgtggtg gaggcatccg gtgccagcct ggagaagggg
     5221 cggcatgacc agctgcttac cgcgcttcgt gcgctgctgt taagtcgcaa aaatccgttt
     5281 ggcgatatca aatcggacgg cacggtgaaa acggctcttc aaaaccttgg tttgggagat
     5341 acaagcggat acgtgggacg ccggctga
//
LOCUS       DAPGUL010000208         5249 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.212, whole genome shotgun sequence.
ACCESSION   DAPGUL010000208 DAPGUL010000000
VERSION     DAPGUL010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5249)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5249)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5249
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.212"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..865
                     /locus_tag="RHX21_004589"
     CDS             <1..865
                     /locus_tag="RHX21_004589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HDV1989665.1"
                     /translation="GTGFGHLAIPRVGQEVIVDFLNGDPDQPIIMGRTYHQENRTPGS
                     LPGTKTQMTIRSKTYKGSGFNELKFDDATGKEQVYIHAQKNMNTEVLNNRTTDVINNH
                     AETIGNNQMIAVTNNQIQTVGVNQIETVGSNQIINVGSVQVETIGLVRALTVGVAYQT
                     TVGGIMNTSVALMQSSQIGLHKSLRVGLGYDVKVGNNVTFTVGKTKKDDTGQTAIYSA
                     GEHLELCCGKARLVLTKDGQIFLNGTKIHLQGKEQVNGDSLLINWNCAASKSPPKTPD
                     EKQDTPDMREY"
     gene            932..5140
                     /locus_tag="RHX21_004590"
     CDS             932..5140
                     /locus_tag="RHX21_004590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310088.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HDV1989666.1"
                     /translation="MSGKPAARQGDMTQYGGPIVQGSAGVRIGAPTGVACSVCPGGMT
                     SGNPVNPLLGAKVLPGETDLALPGPLPFILSRTYSSYRTRTPAPVGVFGPGWKAPSDI
                     RLQLRDDALVLNDNGGRSIHFEPLLPGEAVYSRSESMWLVRGGKAAQPDGHTLAWLWG
                     ALPPDIRLSPHLYLATNSAQGPWWILGWSERVPGAEDVLPAPLPPYRVLTGLADRFGR
                     TLTYRREAAGDLAGEITGVTDGAGREFRLVLTTQAQRAEEARTSSLSSSDSSRPLSAS
                     PFPDTLPGTEYGPDRGIRLSAVWLMHDPAYPESLPGAPLARYTYTEAGELLAVYDRSN
                     TQVRAFTYDAQHPGRMVAHRYAGRPEMRYRYDDTGRVVEQLNPAGLSYRYQYEQDRIT
                     VTDSLNRREVLHTEGGAGLKRVVKKELADGSVTHSGYDAAGRLTAQTDAAGRRTEYGL
                     NVVSGDITDITTPDGRETKFYYNDGNQLTAVVSPDGLESRRAYDEPGRLVSETSRSGD
                     VIRYAYDNPHSELPATTTDATGSTRQMTWSRYGQLLAFTDCSGYQTRYEYDRFGQMTA
                     VHREEGISLYRRYDNRGRLTSVKDAQGRETRYEYNAAGDLTAVITPDGNRSETQYDAW
                     GKAVSTTQGGLTRSMEYDAAGRVISLTNENGSHSVFSYDALDRLVQQGGFDGRTQRYH
                     YDLTGKLTQSEDEGLVTLWYYDESDRITHRTVNGEPAEQWQYDDHGWLTDISHLSEGH
                     RVAVHYGYDDKGRLTGERQTVENPETGELLWQHETTHAYNEQGLANRVTPDSLPPVEW
                     LTYGSGYLAGMKLGDTPLLEYTRDRMHRETVRSFGSMAGSNAAYKLTSTYTPAGQLQS
                     QHLNSLVYDRDYGWNDNGDLVRISGPRQTREYGYSATGRLESVRTLAPDLDIRIPYAT
                     DPAGNRLPDPELHPDSTLTAWPDNRIAEDAHYVYHYDEYGRLTEKTDLIPAGVIRTDD
                     ERTHHYHYDSQHRLVFYTRIQHGEPLVESRYLYDPLGRRMAKRVWRRERDLTGWMSLS
                     RKPEMTWYGWDGDRLTTVQTDTTRIQTVYQPGSFAPLIRIETDNGEREKAQRRSLAEK
                     LQQEGSEDGHGVVFPAELVRLLDRLEEEIRADRVSSESRAWLAQCGLTVEQLARQVEP
                     EYTPARKVHFYHCDHRGLPLALISEDGNTAWRGEYDEWGNQLNEENPYYLHQPYRLPG
                     QQHDEESGLYYNRNRYYDPLQGRYITQDPIGLAGGWNLYNYPLNPIIRMDPLGLYNLY
                     QLLYDVWHDDSYGTSSIDITGSGDLISLGGHAGLGVAFAKKKGEMLSDICIYATACGH
                     AGIGGGINAAITYSETKSLPTSGVSNSVGVTVGGGVGGHFAYTYVVDVDNPESSTESV
                     GIGAGVDASVMTLACRTWQECWVN"
BASE COUNT         1223 a         1385 c         1696 g          945 t
ORIGIN      
        1 aggcaccggt tttggccacc tggcgatacc gcgtgtgggt caggaggtga ttgtggactt
       61 cctcaacggc gatccggacc agccgattat tatggggcgt acctaccacc aggaaaaccg
      121 cacacccggc agcctgccgg ggacgaagac gcagatgacc attcgttcga aaacctataa
      181 gggcagcggg tttaatgaac tgaagtttga cgatgcgaca gggaaagaac aggtctacat
      241 ccacgcgcag aagaacatga acaccgaggt gctgaataac cgcaccacgg atgtgataaa
      301 caaccatgct gagaccattg gcaacaatca gatgattgcg gttaccaaca atcagataca
      361 gacggtgggc gttaaccaga tagagacggt gggcagtaac cagatcatta acgtgggttc
      421 tgttcaggtg gaaacgattg gacttgttcg tgcgctgacc gtgggcgtgg cgtaccagac
      481 gacggtaggt ggcattatga acacttcggt ggctctgatg cagtcctcgc agatcggttt
      541 gcataaatcg ttgagggtcg ggctgggtta tgacgtcaaa gtcggaaata acgttacctt
      601 caccgttggt aaaacgaaaa aggatgatac cgggcagacc gcgatttact ccgccggtga
      661 gcatctggag ctctgctgtg gtaaggcaag gctggtgctg acgaaggacg gacaaatttt
      721 tctcaacggc acaaaaattc atttgcaggg taaggagcag gttaatggtg actcactgtt
      781 gattaactgg aactgtgcag cctcgaaatc cccaccgaag acccctgatg aaaagcagga
      841 tacgccggat atgagagagt actgatcccg tacctgttcg gtattcagta acaaacaagc
      901 attaaaaata aacagaagaa ggaattgaat catgagcgga aaaccagcgg cgcgtcaggg
      961 agatatgact cagtatggcg gtcctattgt ccagggttcg gcaggtgtaa gaattggcgc
     1021 gcccaccggc gtggcgtgct cggtgtgtcc gggcgggatg acttcgggca acccggtaaa
     1081 tccgctgctg ggggcgaagg tgctgcccgg cgagacggac cttgcgctgc ccggcccgct
     1141 gccgttcatt ctctcccgca cctacagcag ctaccggacc aggacacccg cgccggtggg
     1201 agtgtttggc cccggctgga aagcgccttc tgatatccgc ttacagctac gcgatgatgc
     1261 actggtactc aacgacaacg gcgggcggag cattcacttt gagccgctgc tgccggggga
     1321 ggcggtgtac agccgcagcg agtcaatgtg gctggtgcgc ggtggtaagg cagcgcagcc
     1381 ggacggccac acgctggcgt ggctgtgggg ggcgctgccg ccggatatcc ggttaagccc
     1441 gcatctttac ctggcgacca acagcgcaca ggggccgtgg tggatactgg ggtggtcaga
     1501 gcgggtgccg ggtgctgagg acgtactgcc agcgccgctg ccgccgtacc gggtgcttac
     1561 cgggctggca gaccgtttcg ggcggacgct gacgtaccgg cgtgaggccg caggcgacct
     1621 ggccggggaa atcaccggcg tgacggacgg tgccgggcgt gagttccgtc tggtactgac
     1681 cacacaggca cagcgggcgg aagaggcccg cacctcttcg ctatcttctt ctgacagttc
     1741 ccgccctctc tcagcctcac cgttccccga cacactgccc ggtaccgaat acggccccga
     1801 caggggcatc cgtctttcgg cggtgtggct gatgcacgac ccggcatacc cggaaagcct
     1861 gcccggtgcg ccactggcgc ggtacacgta tacggaagcc ggtgaactgc tggcggtata
     1921 tgaccgcagc aatacgcagg tgcgcgcttt cacgtatgac gcgcagcacc cgggccggat
     1981 ggtggcgcac cgttacgcgg gaaggccgga gatgcgctac cgctacgacg ataccgggcg
     2041 ggtggtggag cagctgaacc cggcaggcct gagttaccgc taccagtatg agcaggaccg
     2101 catcaccgtc acggacagcc tgaaccggcg tgaggtgctg catacagaag gcggggccgg
     2161 gctgaagcgg gtggtgaaaa aagaactggc ggacggcagc gtcacgcaca gcgggtatga
     2221 cgcggcagga aggctaacgg cgcagacgga cgcggcggga cggcggacag agtacggtct
     2281 gaatgtggtg tccggcgata tcacggacat caccacaccg gacgggcggg agacgaaatt
     2341 ttactataac gacgggaacc agctgacggc ggtggtgtcc ccggacgggc tggagagccg
     2401 ccgggcatat gatgaaccgg gcaggctggt atcggagaca tcgcgcagtg gggacgtcat
     2461 ccggtatgct tatgataatc cgcacagtga attaccggcc acgacaacag atgcgacggg
     2521 cagcacccgg cagatgacct ggagccgcta cgggcagttg ctggcgttca ccgactgctc
     2581 gggctaccag acccgatatg aatacgaccg cttcggccag atgacggcgg tccaccgcga
     2641 ggaaggcatc agcctttacc gccgctatga caaccgtggc cggttaacct cggtgaaaga
     2701 cgcacagggc cgtgaaacgc ggtatgaata caacgccgca ggcgacctga ctgccgttat
     2761 caccccggac ggcaaccgga gcgagacaca gtacgatgcg tggggaaagg cggtcagcac
     2821 cacgcagggc gggctgacgc gcagtatgga gtacgatgct gccggacgtg tcatcagcct
     2881 gaccaacgag aacggcagcc acagcgtctt cagttacgat gcgctggacc ggctggtaca
     2941 gcagggcggc tttgacgggc ggacgcaacg ttatcattat gacctgaccg gaaaactcac
     3001 acagagtgag gatgaggggc ttgtcaccct ctggtactac gatgaatcgg accgtatcac
     3061 tcaccgcacg gtgaacggcg aaccggcaga gcagtggcag tatgatgacc acggctggct
     3121 gacagacatc agccacctga gcgaaggcca ccgtgtcgct gtccactacg gctacgacga
     3181 taagggccgc ctgaccggcg aacggcagac ggtggagaac ccggagacgg gggaactgct
     3241 gtggcagcat gagacaacac acgcctacaa cgaacagggg ctggcaaacc gcgtcacgcc
     3301 ggacagcctg ccgccggtgg agtggctgac ctacggcagc ggttatctgg cgggcatgaa
     3361 gcttggcgac acgccgctgc tggagtacac gcgcgaccgc atgcaccggg agacggtgcg
     3421 cagctttggc agcatggcag gcagtaatgc cgcatataaa ctgaccagca catacacccc
     3481 cgcaggccag ttacagagcc agcacctgaa cagcctggtg tatgaccgtg actacgggtg
     3541 gaatgacaac ggcgacctgg tgcgcatcag cggcccgcga cagacgcggg aatacggcta
     3601 cagcgccacg ggcaggctgg agagcgtgcg taccctcgca ccggacctgg acatccgcat
     3661 cccgtatgcc accgacccgg cgggaaaccg cctgccggac ccggagctgc acccggacag
     3721 taccctcacg gcgtggccgg ataaccgcat cgcagaggat gcgcactatg tttaccacta
     3781 tgatgaatac ggcagactga cggagaagac ggaccttatc ccggcgggtg ttatccggac
     3841 ggacgacgag cggacccacc actaccacta cgacagccag caccgtctgg tgttctacac
     3901 gcggatacag catggcgagc cactggtcga gagccgctac ctctacgacc cgctgggacg
     3961 gcgaatggcg aaacgggtat ggcggcggga gcgtgacctg acggggtgga tgtcgctgtc
     4021 gcgtaaaccg gagatgacgt ggtacgggtg ggacggcgac cggctgacga cggtacagac
     4081 cgacaccacg cgtatccaga cggtatatca gccggggagc ttcgcgccgc tcatccgcat
     4141 cgaaacagac aacggcgagc gggagaaagc gcagcgccgc agcctggcgg agaagctgca
     4201 gcaggaaggg agcgaggacg ggcacggcgt ggtatttccg gctgaactgg tgcggctgct
     4261 ggacaggctg gaggaagaaa tccgggcaga ccgcgtgagc agtgaaagcc gggcgtggct
     4321 tgcgcagtgc gggctgacgg tggagcaact ggccagacag gtggagccgg aatacacacc
     4381 ggcgcgaaaa gttcattttt accactgcga ccaccggggc ctgccgctgg cgctcatcag
     4441 cgaagacggc aatacggcgt ggcgcgggga gtatgatgaa tggggcaacc agcttaatga
     4501 agagaacccg tattacctgc accagccata ccgtctgccg gggcagcagc atgatgagga
     4561 atcagggctg tactataacc ggaaccggta ctatgacccg ctacagggga ggtatattac
     4621 acaagacccc attgggctgg cggggggatg gaacctgtat aattacccac tgaatccgat
     4681 aataaggatg gatcctttgg gtttgtataa tttatatcaa ttattatatg atgtttggca
     4741 tgatgattca tatggaacat catcaattga tattactggc agtggagatc taatatcatt
     4801 aggtggtcat gcaggacttg gcgttgcgtt tgctaaaaag aaaggtgaaa tgttatctga
     4861 tatttgtatt tatgctacag catgcggaca tgcaggaatt ggtggtggga taaatgcggc
     4921 tatcacatat tctgagacca agtctttacc tacatcggga gtcagcaatt cagtaggtgt
     4981 aacggttggc ggcggagttg gggggcattt tgcgtatact tatgtagtgg atgttgataa
     5041 tccagaatca tcgacagaat ctgttggtat cggtgcaggt gttgacgctt cagttatgac
     5101 tctggcttgt agaacgtggc aagaatgctg ggtcaattaa caggaggaaa tatgaaaaaa
     5161 tatatatttt tagttttatt tttattgtgt ggttgttctc cagtggacat agagccagct
     5221 agacaagaag ttaatatctt tcgtggttt
//
LOCUS       DAPGUL010000209         5188 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.213, whole genome shotgun sequence.
ACCESSION   DAPGUL010000209 DAPGUL010000000
VERSION     DAPGUL010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5188
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.213"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            241..489
                     /gene="repA"
                     /locus_tag="RHX21_004591"
     CDS             241..489
                     /gene="repA"
                     /locus_tag="RHX21_004591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication regulatory protein RepA"
                     /protein_id="HDV1989667.1"
                     /translation="MSQTENAVTSSSGTKRAYRKDNPLTLAERQQASLARKRATHKEL
                     RVFIPAALKAQLQEMCEAEGVTQAEMIAELIRQKSAFS"
     gene            736..810
                     /gene="tap"
                     /locus_tag="RHX21_004592"
     CDS             736..810
                     /gene="tap"
                     /locus_tag="RHX21_004592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001370046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepA leader peptide Tap"
                     /protein_id="HDV1989668.1"
                     /translation="MPGKVQDFFLCSLLLRIVSAGWCD"
     gene            803..1660
                     /gene="repA"
                     /locus_tag="RHX21_004593"
     CDS             803..1660
                     /gene="repA"
                     /locus_tag="RHX21_004593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="incFII family plasmid replication initiator
                     RepA"
                     /protein_id="HDV1989669.1"
                     /translation="MTDLQQTYYRQVKNPNPVFTPRKGAGTLKFCEKLMEKAVGFTSR
                     FDFAIHVAHARSRGLRRRMPPVLRRRAIDALLQGLCFHYDPLANRVQCSITTLAIECG
                     LATESGAGKLSITRATRALTFLSELGLITYQTEYDPLIGCYIPTDITFTPALFAALDV
                     SEVAVASARRSRVEWENRQRKKQGLDALGMDELIAKAWRFVRERFRSYQTELKSRGIK
                     RARARRDANRERQDIVTLVKRQLTREISEGRFTANREAIKREVERRVKERMILSRNRN
                     YSRLATASP"
     gene            2574..2843
                     /locus_tag="RHX21_004594"
     CDS             2574..2843
                     /locus_tag="RHX21_004594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989670.1"
                     /translation="MAQVNMSLRIDAELKDAFMAAAKSMDRNGSQLIRDFMRQTVERQ
                     HNTWFRDQVAAGRQQLEHGDVLPHDMVESSAAAWRDEMSRKVAGK"
     gene            2840..3121
                     /locus_tag="RHX21_004595"
     CDS             2840..3121
                     /locus_tag="RHX21_004595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001585073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDV1989671.1"
                     /translation="MMEIFWTMLASQDRKRIREYIAEQNLMAAIELDERIGYSASSLA
                     GQPYKGRNGRVEGTRELVIHPHFVLVYEVDSQWGKVYILRVLHTAQKWP"
     gene            3206..3553
                     /locus_tag="RHX21_004596"
     CDS             3206..3553
                     /locus_tag="RHX21_004596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001563283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989672.1"
                     /translation="MPFEQKKARAIALMDSKKMWRSNYAPPLLRILWRLGIRLPPLPF
                     MPFWQVAVLTGGLWGTSWGCAMWFIYWGPSGMVAGEAIIISITGGFLFGLLTASFHWW
                     RRKVNRLPPWDDV"
     gene            complement(3571..4161)
                     /locus_tag="RHX21_004597"
     CDS             complement(3571..4161)
                     /locus_tag="RHX21_004597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001545742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989673.1"
                     /translation="MTQSRRPSPLQRRVLIVLAALDEKRPGPVLTRDIERVLERSGEA
                     PVYGPNLRASCRRLEDAGWLRTLRAPNLQLAVELTDAGRAVAQPLLLAEQDRLRAEQR
                     AAEVVVLPLVPAAGLPADGTSATDLAVELNGITYQACRGDFVVRLDGSTCLQLWNKEG
                     RVVCLEGDPLEVAQWLQACHDAGIEVRVQINESSVP"
     gene            complement(4161..4415)
                     /locus_tag="RHX21_004598"
     CDS             complement(4161..4415)
                     /locus_tag="RHX21_004598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989674.1"
                     /translation="MDEERVFSLSYEQLTRIAEKNIRECGLDNQSARCISELKASALL
                     WLWYELAIHGAPQNNHAQARERIDTDYQRLKKLIWSEGDS"
     gene            4767..>5188
                     /locus_tag="RHX21_004599"
     CDS             4767..>5188
                     /locus_tag="RHX21_004599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000785695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4238 domain-containing protein"
                     /protein_id="HDV1989675.1"
                     /translation="MADPFNLQTDVVRQHTVPRFLLKHFSTPGKGKRQRLYAFDKAAG
                     RAYATTPDDATVRNTFYNLDNHPDRLSLEPLLGIYEHHAAPVIAALLAHRDIRRLTDD
                     ERYRLAVFVAVQRARTFGELERISGMISVLTDKMEAIGS"
BASE COUNT         1235 a         1376 c         1365 g         1212 t
ORIGIN      
        1 ggtatttcag gggcagacac ccgacatgcc agaaacagcc ggtcccgccc ggggccggca
       61 cacaggttaa ggcatttcca tcttttcagt catttcatta tcaaaatcac attaaacggt
      121 cgtaatcaga catgatttgt gcgccaacac agatcatcgt cacaactttc aagtcgctga
      181 tttcaaaaaa ctgtagtatc ctctgcgaaa cgatccctgt ttgagaattg aggaggcgag
      241 atgtcgcaga cagaaaatgc agtgacttcc tcatcaggta caaagcgagc atatagaaaa
      301 gataatcctc tgacgcttgc agaacgtcag caggcatccc tggcaagaaa acgagccaca
      361 cataaagaac tcagagtgtt tattcctgct gcgttaaaag cgcaattgca ggagatgtgt
      421 gaagctgagg gtgttactca ggctgagatg attgccgaac tgataaggca gaagagtgct
      481 tttagctaac tgaaatgtag cgacatcaca ttcttgcctg tttctggtgt gcgtgataga
      541 ttgctgatcg tttaaggaat tttatggctg gccacgccat aaggtggcaa ggaactggtt
      601 ctgatgtgga tgtacaggag ccagaaaagc aaaaaccccg ataatcttct ttaactttgg
      661 cgagtacaga aagattaccg gggccatcta aaaaccgtat agccagcaat tcagctatgc
      721 ggggagtata gctatatgcc cggaaaagtt caagacttct ttctgtgctc actccttctg
      781 cgcattgtaa gtgcaggatg gtgtgactga tcttcaacaa acgtattacc gccaggtaaa
      841 gaacccgaat ccggtgttta caccccgtaa aggtgccgga acgctgaagt tctgcgaaaa
      901 actgatggaa aaggcggtgg gcttcacctc ccgttttgat ttcgccattc atgtggcgca
      961 tgcccgttcg cgtggtctgc gtcggcgcat gccaccggta ctgcgtcgcc gggccattga
     1021 tgcgctgctg caggggctct gttttcacta tgatccgctg gccaaccgcg tccagtgctc
     1081 catcaccacg ctggccattg agtgcggact ggcgacagag tccggtgcag gaaaactctc
     1141 catcactcgt gccacccgtg ccctgacgtt cctgtcagag ctggggttga ttacctacca
     1201 gacggaatat gacccgctta tcgggtgcta cattccgacc gacatcacgt tcacaccggc
     1261 actgtttgcc gctctcgatg tgtctgaggt ggcggtggct tccgcacgcc gcagtcgtgt
     1321 ggaatgggaa aacagacagc gcaagaagca gggactggat gcactgggta tggatgaact
     1381 gatagcgaaa gcctggcgtt ttgtgcgtga gcgtttccgc agttaccaga cagagcttaa
     1441 gtcccgtgga ataaaacgtg cccgtgcgcg tcgtgatgcg aacagggaac gtcaggatat
     1501 cgtcaccctg gtgaaacggc agctgacgcg tgaaatctcg gaagggcgct tcactgccaa
     1561 tcgtgaggcg ataaaacgcg aagtggaacg tcgtgtgaag gagcgcatga ttctgtcacg
     1621 taaccgcaat tacagccggc tggccacagc ttccccctga aagtgacctc ctctgaataa
     1681 tccggcccgc accggaggca tctgcacgcc tgaagcctgt cggcgaacaa aaaaacagca
     1741 ccgcatacaa aaaacaacct catcatccac cttcaggtgc atccggtccc tcctgttttt
     1801 gatacaaaac acgcctcaca gacgaggaat tttgcttatc cacatttagc tgcaagggac
     1861 ttccccataa ggttacaacc gttcatgtca taaagcgcca tccgccagcc ttacaggatg
     1921 caatgtatct tttaaacacc tgtttatatc tcctttaaac tacttaacta cattcattta
     1981 aaaagaaaac ctgttcactg tctgtcctgt ggacagacag atatgcacct cccaccgcaa
     2041 gcggcgggcc ccgaccggag ccactttagt tacaacactc agatacaacc accaaaaaaa
     2101 acccggtccc gcgcagaact gaaaccgcaa agccccccct cataactgaa aagcggcccc
     2161 gccccggccc aaagggccgg aacagagtcg cttttaatta tgaatgttgt aactaagcat
     2221 ttccatcgct gtcagtcttc tcgctggaag tatcgagtac acgctcgtaa gcggccctga
     2281 cggcccgcta acgcggagat acgccccgac ttcgggtaaa ccctcgtcgg gaccactccg
     2341 accgcgcaca gaagcgctat catggctgaa agcgggtatg gcttagcagg gcggggatgg
     2401 gacaggtgaa atctatcaat cagtaccggc ttacgccggg cttcggcggt tttactccgg
     2461 tatcatatgc aacaatggag tgccgccttc catgccgctg acgcggcata tcctggtgac
     2521 gatatctgaa tcgttatata ctgtgtatat acgtagtaat gacgaggtga taaatggcac
     2581 aggttaatat gagtttaaga atcgacgctg aactgaagga tgcttttatg gccgctgcaa
     2641 aaagcatgga tcgtaatggc tctcagttaa tccgggattt tatgcgccag accgttgaac
     2701 ggcagcataa tacctggttc cgcgaccagg ttgcggcagg acgtcagcaa ctcgagcacg
     2761 gcgatgtgct tccccatgac atggtcgaat catctgctgc agcatggagg gatgaaatga
     2821 gcaggaaggt cgccggtaaa tgatggagat attctggacc atgctggcca gccaggacag
     2881 gaagcgcatt cgtgagtaca ttgcggagca gaacctgatg gccgccattg aactggacga
     2941 acggattggt tattcagcca gcagcctggc cgggcagccg tataaaggcc gcaacggtcg
     3001 tgtggaaggt acccgggaac tggttattca cccacatttt gttctggttt atgaggtcga
     3061 cagccagtgg ggaaaagtgt atatcctgcg agtattgcat actgcacaga agtggccata
     3121 gaggggctgt ccggatatca cagcatgata ataatcaata acaataagct gtgtcacgtt
     3181 tacatcatgg aacggaggtg ctcctgtgcc ctttgagcag aaaaaagccc gggccattgc
     3241 cctgatggac agcaaaaaga tgtggcggag caattatgcc cctcctcttc tgcgtattct
     3301 ctggcggctg ggtatccggc ttccgccatt accctttatg ccgttctggc aggtcgcggt
     3361 gctgacgggg ggcttatggg gcacttcctg gggatgtgca atgtggttta tctactgggg
     3421 gccgtcagga atggtggcag gtgaggccat tattataagt atcacgggtg gttttttgtt
     3481 cggactgctc acggcctctt tccactggtg gcgcaggaaa gttaaccggc tgccaccatg
     3541 ggatgacgtg taaaccatgc aggcatgttt ttacgggacg ctactttcat ttatctgtac
     3601 gcgaacctct attcctgcgt catgacaggc ctgcagccac tgcgccactt ccagcggatc
     3661 gccctccagg cataccaccc tgccttcttt attccataac tgcagacagg tgctgccgtc
     3721 gagacgcacc acaaaatccc cacggcaggc ctgatacgtt atgccgttca gctctaccgc
     3781 cagatcagtg gcagaagtgc cgtctgcggg cagacctgct gccgggacca gcggcagtac
     3841 gacgacttct gccgcacgct gttctgcccg gaggcggtcc tgttctgcca gcagcagagg
     3901 ctgtgccacg gcccggccgg cgtccgtcag ctccactgcc agctgcaggt tcggagcgcg
     3961 cagggtacga agccagccgg catcctccag acgacggcag gaggcgcgca ggtttggccc
     4021 gtagaccggg gcttccccgc ttcgctccag cacccgttct atgtcccgcg tcagcacggg
     4081 tcccggccgt ttttcatcaa gggcagccag cacaatcagc actctccgct gcagtggcga
     4141 cggtcggcgg ctctgagtca ttaactgtca ccctccgacc agatgagttt tttgaggcgc
     4201 tgataatcgg tatcgatgcg ttcccgggcc tgtgcgtgat tgttctgtgg cgcaccatga
     4261 atggccagtt cataccacaa ccacagcaga gctgaggcct tcaattcact aatacacctg
     4321 gcgctctggt tgtccagccc acattcacgg atattttttt ccgctattcg ggttagttgc
     4381 tcatagctga gtgaaaacac cctttcttca tccatcctgc acgctccatc tgataatgtt
     4441 ctgacaggta aaaatcatgt catgtatgat ttatgtattc ttagtttctg ataatatcag
     4501 atattgtttc atttataatg atgaaaatca tatctgatat gattttatgt gtattgctaa
     4561 attatcatat cagttgcccg tttcccgtcg tgcagatccg gtttccggcg gttccggaga
     4621 tttaaattcc atcggtactg acagggcgtt aaacacaggt attatcgaac ggttctgttt
     4681 tctaatgcta agctgcaaac cagctgccca tgccgtcaat acagatgcac cgatgcgctt
     4741 gcgtggcttt tcagggagat aaagttatgg ccgatccatt caatctgcag accgatgtgg
     4801 tcaggcagca tacggttccc cgttttttac tgaagcattt cagtacgccg ggaaagggta
     4861 agcggcagcg cttatacgcc tttgacaagg ctgccgggcg cgcctatgcc accacgccgg
     4921 atgacgcgac cgtccgcaac acgttctaca acctcgataa tcacccggac cgtctgagtc
     4981 ttgaaccact gctggggatt tacgagcacc acgcggcacc ggtaattgca gccctgctgg
     5041 cgcacaggga tattcgcagg ctgacagatg atgaacgcta caggctggcc gtgtttgttg
     5101 ccgtgcagcg cgcacgaacc ttcggtgaac tggagcgtat ctcaggcatg atttcggtgc
     5161 ttaccgataa gatggaggcc atcggctc
//
LOCUS       DAPGUL010000210         5131 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.214, whole genome shotgun sequence.
ACCESSION   DAPGUL010000210 DAPGUL010000000
VERSION     DAPGUL010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5131)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5131)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5131
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.214"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..391)
                     /locus_tag="RHX21_004600"
     CDS             complement(<1..391)
                     /locus_tag="RHX21_004600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HDV1989676.1"
                     /translation="MTTVTHNSTTPSVSVTAASGNNPPQLVATLVPDEQRISFWPQHF
                     GLIPQWVTLEPRVFGWMDRLCEDYCGGIWNLYTLNNGGAFMAPEPDDDDDETWVLFNA
                     MNGNRAEMSPEAAGIAACLMTYSHHACR"
     gene            complement(483..1301)
                     /locus_tag="RHX21_004601"
     CDS             complement(483..1301)
                     /locus_tag="RHX21_004601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HDV1989677.1"
                     /translation="MRLASRFGHVNQIRRDRPLTHEELMHYVPSIFGEDRHTSRSERY
                     AYIPTITVLESLQREGFQPFFACQTRVRDPGRRGYTKHMLRLRRDGEINGQHVPEIIL
                     LNSHDGTSSYQMLPGYFRFVCQNGCVCGQSLGEVRVPHRGNVVEKVIEGAYEVVGVFD
                     RIEEKRDAMQSLVLPPPSRQALAQAALTYRYGDEHQPVTTADILTPRRREDYGKDLWS
                     AYQTIQENMLKGGISGRSARGKRIHTRTIHSIDTDIKLNRALWVMAETLLESMR"
     gene            complement(1629..4475)
                     /gene="ag43"
                     /locus_tag="RHX21_004602"
     CDS             complement(1629..4475)
                     /gene="ag43"
                     /locus_tag="RHX21_004602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin Ag43"
                     /protein_id="HDV1989678.1"
                     /translation="MKRHLNTSYRLVWNHITGTLVVASELARSRGKCAGVAVALSLTA
                     VTSVQALAADTIVQAGETVNGGTLANHDNQIVLGTANGMTISTGLEYGPDNEANTGGQ
                     WIQNGGTANNTTVTGGGLQRVNAGGSVSDTVISAGGGQSLQGQAVNTTLNGGEQWVHE
                     GGIATVTVINEKGWQAVKSGAMATDTVVNTGAEGGPDAENGDTGQTVYGDAVRTTINK
                     NGRQIVAAEGTANTTVVYAGGDQTVHGHALDTTLNGGYQYVHNGGTASGTVVNSDGWQ
                     IIKEGGLADFTTVNQKGKLQVNAGGTATHVTLKQGGALVTSTAATVLGSNRLGNFTVE
                     NGKADGVVLESGGRLDVLEGHSAQKTRVDDGGTLAVSAGGKATGVTMTSGGALIADSG
                     ATVEGTNASGKFSIDGISGQASGLLLENGGSFTVNAGGLASNTTVGHRGTLMLAAGGS
                     LSGRTQLSKGASMVLNGDVVSTGDIVNAGEIYFDNQTTPDAVLSRAVAKGNAPVTFHK
                     LTTSNLTGQGGTINMRVRLDGSNTSDQLVINGGQATGKTWLAFTNVGNSNLGVATTGQ
                     GIRVVDAQNGATTEEGAFALSRPLQAGAFNYTLNRDSDEDWYLRSENAYRAEVPLYAS
                     MLTQAMDYDRILAGSRSHQTGVSGENNSVRLSIQGGHLGHDNNGGIARGATPESSGSY
                     GFVRLEGDLLRTEVAGMSLTTGVYGAAGHSSVDVKDDDGSRAGTVRDDAGSLGGYLNL
                     THTSSGLWADIVAQGTRHSMKASSDNNDFRARGWGWLGSLETGLPFSITDNLMLEPQL
                     QYTWQGLSLDDGQDNAGYVKFGHGSAQHVRAGFRLGSHNDMTFGEGTSSRDTLRDSAK
                     HRVSELPVNWWVQPSVIRTFSSRGDMSMGTAAAGSNMTFSPSQNGTSLDLQAGLEARV
                     RENITLGVQAGYAHSVSGSSAEGYNGQATLNVTF"
     gene            complement(4847..>5131)
                     /locus_tag="RHX21_004603"
     CDS             complement(4847..>5131)
                     /locus_tag="RHX21_004603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase family protein"
                     /protein_id="HDV1989679.1"
                     /translation="AVSACTGWELDTLVSALMTALPDHAASPLMTRLQDELRTESVRS
                     QAREQFTGAVDRIFDTAESVCVASVARTVLRAVRDTVVSVARAVWNWIFF"
BASE COUNT         1092 a         1483 c         1384 g         1172 t
ORIGIN      
        1 tacgacaggc atgatgactg tacgtcatca gacaggcggc aataccggcg gcttccgggc
       61 tcatttcagc gcggttaccg ttcatggcat tgaacagtac ccatgtttcg tcatcatcgt
      121 catccggttc gggtgccata aatgccccgc cgttgttcag ggtgtacaga ttccagatac
      181 caccgcagta gtcttcgcac agacggtcca tccagccgaa gacacggggc tccagggtca
      241 cccactgtgg aatgaggcca aaatgctgcg gccagaagct gatgcgctgt tcatcaggga
      301 cgagagtagc aaccagctga ggtgggttat tccctgatgc agcggttacg gaaacagaag
      361 gtgtggtgga attatgcgta acggttgtca tgagattatt ccttataaaa agtaaatgaa
      421 tggaagaatg tccggaggca gggacggaag tgagtcagga ctgcgctttc agggaaaagg
      481 catcagcgca tgctctccag cagtgtttct gccatcaccc acaacgcccg gttgagctta
      541 atgtcggtgt cgatgctgtg aatggtacgg gtatggatac gttttcctct ggcactgcga
      601 ccggaaatcc cgcctttcag catattctcc tggatggtct gataagcact ccacaggtcc
      661 ttaccgtaat cctcccggcg tcgtggcgtc agaatgtcgg cggtggtgac gggctgatgt
      721 tcgtcaccat aacggtaagt cagtgccgcc tgtgccagcg cctggcgtga cggtggcggc
      781 aggaccagcg actgcatggc atcacgcttc tcctctatcc ggtcaaacac gcccaccacc
      841 tcgtaagccc cttcgataac tttctccacc acatttcccc ggtgtggaac acgcacttcc
      901 cccagagact ggccacagac gcacccgttc tggcagacga acctgaagta acccggcagc
      961 atctggtagc tggaagtacc gtcatgggag ttcagcagga tgatttcagg gacatgttgt
     1021 ccgtttatct ccccgtcacg gcgcagacgc agcatgtgtt tggtgtatcc ccggcggccc
     1081 gggtcgcgca cgcgggtctg gcaggcgaag aagggctgaa agccctcccg ctgcaggctt
     1141 tccagtacgg tgatggtggg aatgtacgca tagcgttcac tgcgggaggt atgccggtct
     1201 tccccaaaaa tactgggcac atagtgcatc agttcttcat gtgtcagcgg gcggtcacgg
     1261 cgtatctggt ttacatgacc aaaacgactt gctaatcgca ttatttgctc cttatgaatg
     1321 agttagcggt ataaatgaaa aagccgcgtc tcccggagaa gacgcggcct gacagatgaa
     1381 atgaatgacg tttattgtct gagaagccct ccactggtga gctgcgtatt ttcatggaag
     1441 gagatcaccc aatatcccca tcgggatcgg gtaataactg gccagactgt gatcaattca
     1501 gatgccattt ggcagtaaaa gggccttcgg gcaataaacg tgatgtacaa cccggcatat
     1561 ctgttgctcc ctgtaagtaa aaggccccgg tcatgatgac cggggcctga aggggagtga
     1621 cctgattatc agaaagtcac attcagtgtg gcctgaccgt tataaccttc agcactgctg
     1681 ccgctgacgc tgtgggcata accggcctga acgcccaggg tgatattttc ccggacacgg
     1741 gcttccagtc cggcctgcag gtccagtgat gtgccattct gtgagggtga gaacgtcatg
     1801 ttactgccgg ctgcggctgt acccatgctc atgtcacccc gggagctgaa agtgcggata
     1861 acagaaggct gtacccacca gttcaccggc agttcactca cacggtgttt tgcactgtcg
     1921 cgcagagtgt cacgggatga ggtgccttcg ccaaaggtca tatcgttgtg gctgcccaga
     1981 cggaagccgg cacgcacatg ttgtgcactg ccatgcccga acttcacata accggcgtta
     2041 tcctggccgt catccaggga gagcccctgc caggtgtact gcagttgtgg ctccagcatc
     2101 aggttgtcag tgatactgaa gggcagaccg gtttccagtg agcccagcca gccccagccc
     2161 cgggcgcgga agtcgttatt atccgatgac gctttcatgc tgtggcgggt tccctgtgcc
     2221 acaatgtcag cccacaggcc ggaggacgtg tgtgtcagat tcaggtatcc gcccaggctg
     2281 ccggcatcat cccggaccgt gccggcgcgg gaaccgtcat catccttaac atcaacggaa
     2341 gaatggcctg cagcaccata cacccctgtc gtcagagaca taccggcaac ctctgttctg
     2401 agcaggtcac cctccagacg gacgaagcca tagctgccgc tgctttccgg cgtggcccca
     2461 cgggcaatac cgccgttgtt atcgtgaccg agatgaccgc cctgaatgct gagacggacg
     2521 ctgttatttt caccgcttac accggtctga tggctgcggg agcctgccag aatccggtca
     2581 tagtccattg cctgtgtcag catggaggca tacaggggga cttcagcacg ataagcattt
     2641 tcactgcgca ggtaccagtc ttcatcgctg tcacggttca gggtgtagtt aaaggcgccg
     2701 gcctgaagcg ggcgactcag ggcaaacgca ccttcttctg tggtggcgcc attctgtgca
     2761 tccacaaccc ggataccctg tccggtggtt gccaccccga ggttgctgtt tccgacattt
     2821 gtaaacgcaa gccaggtttt gccggttgcc tgaccaccat taatcaccag ctggtcagag
     2881 gtattgctgc catcaaggcg aacacgcata ttgatggtgc caccctgacc ggtgaggtta
     2941 ctggttgtca gtttatggaa cgttaccggg gcgttgcctt ttgcaacagc acggctcagt
     3001 acggcgtccg gtgttgtctg attatcaaag taaatctccc ctgcgttaac aatatcgccg
     3061 gtactgacca catcaccatt cagtaccatg ctggcgcctt tactgagctg tgttctgcca
     3121 ctcagacttc ccccggcagc cagcatcagt gttccacgat gtccgacagt ggtgttgctg
     3181 gccagtcctc cggcattaac cgtaaagctg ccgccatttt ccagcagcag gccgctggcc
     3241 tgaccggata tgccatcaat actgaactta ccgctggcat tggtcccctc aacagtggca
     3301 ccactgtctg caatcagggc accaccggat gtcatggtga cacctgttgc cttaccaccg
     3361 gcagacactg ccagggtacc gccgtcatcc acccgtgttt tctgcgctga atggccttcc
     3421 agtacatcca ggcgaccgcc ggactccaga acaacgccgt cagccttacc gttttccacc
     3481 gtgaaattgc ccagacggtt gctgccaaga accgttgccg cagtactggt gaccagtgct
     3541 ccaccctgtt tcagggtgac atgtgtggcg gtaccaccgg cgttcacctg cagtttgcct
     3601 ttctggttaa cggtggtgaa atccgccaga ccaccttcct tgataatctg ccagccgtca
     3661 ctgtttacaa cagtgccaga cgccgtaccg ccgttgtgca catactggta ccccccattc
     3721 agcgtggtat ccagtgcgtg accatgtaca gtctggtcgc cgccggcata aaccacagtg
     3781 gtatttgccg ttccttcagc agccacaatc tgacgaccat ttttattgat ggtggtgcgt
     3841 acggcatctc cgtagacggt ctgcccggta tcaccatttt ctgcatccgg tcccccttcc
     3901 gcgccggtat tcacaaccgt gtcggttgcc attgcgccgg atttgacggc ctgccagccc
     3961 ttctcattaa tgacggtaac cgttgcaatc ccgccttcat gtacccactg ctcaccgccg
     4021 ttcagagtgg tattcactgc ctgcccctga aggctctgtc cgcctccggc actgataacc
     4081 gtgtctgaaa cgcttcctcc ggcattcact ctctgaagac caccaccggt gacagtagtg
     4141 ttgttggcgg taccgccatt ttgtatccat tggccgccgg tattcgcctc gttatccggc
     4201 ccatactcca gcccggtact gatggtcatt ccgttggccg taccgaggac aatctggttg
     4261 tcgtgatttg ccagtgtccc gccgttcacg gtttcacccg cctgtacaat cgtgtcagca
     4321 gccagcgcct ggactgacgt gacagcagta agagacagtg caaccgccac accggcgcat
     4381 tttccccgtg agcgggccag ttcggaagcc accacaaggg tgcccgtaat gtgattccat
     4441 accagcctgt agctggtgtt cagatgtcgt ttcataagct tttccttaca gagggtgaat
     4501 aaaaaagccg gtacccacaa atgtggatac cggcaggtac aaaacagcat ggtcagataa
     4561 agtggttttt cccggacata aatgcttccc ctctctcatc cgccagagaa gtatcagtcc
     4621 gttgtgtgca attccgttct gcatgatgaa gagattcagc tgccttttcg caggccatta
     4681 accactataa acgatcgata gcaacgatcg atacctgttt tatcgatcgt tttattctat
     4741 taacgacaag gcggtcacgc aagagaaaga ggtggatatg agggggttgt gtcatgtttt
     4801 cagttggtta acgcaatgta atcaggcatt tcccctggca gactgttcag aagaaaatcc
     4861 agttccatac agcgcgggca acagagacca ccgtgtcacg gacggcacgc agaaccgtac
     4921 gggcaacaga ggcaacacag acgctctccg ccgtgtcaaa tatccggtcc accgcaccgg
     4981 taaactgttc acgggcctga gaccggacag attccgtgcg cagctcgtcc tgcaggcggg
     5041 tcatcagggg actggcggca tggtcgggaa gcgctgtcat gagcgcactg accagcgtat
     5101 ccagttccca gccggtgcag gccgatacgg c
//
LOCUS       DAPGUL010000211         5100 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.215, whole genome shotgun sequence.
ACCESSION   DAPGUL010000211 DAPGUL010000000
VERSION     DAPGUL010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5100
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.215"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            682..2190
                     /gene="ltrA"
                     /locus_tag="RHX21_004604"
     CDS             682..2190
                     /gene="ltrA"
                     /locus_tag="RHX21_004604"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDV1989680.1"
                     /translation="MQRKLATWAVTDPSLRIQRLLRLITQPEWLAEAARITLSSKGAH
                     TPGVDGVNKTMLQARLAVELQILRDELLSGHYQPLPARRVYIPKSNGKLRPLGIPALR
                     DRIVQRAMLMAMEPIWESDFHTLSYGFRPERSVHHAIRTVKLQLTDCGETRGRWVIEG
                     DLSSYFDTVHHRLLMKAVRRRISDARFMTLLWKTIKAGHIDVGLFRAASEGVPQGGVI
                     SPLLSNIMLNEFDQYLHERYLSGKARKDRWYWNNSIQRGRSTAVRENWQWKPAVAYCR
                     YADDFVLIVKGTKAQAEAIREECRGVLEGSLKLRLNMDKTKITHVNDGFIFLGHRIIR
                     KRSRYGEMRVVSTIPQEKARNFAASLTALLSGNYSESKVDMAEQLNRKLKGWAMFYQF
                     VDFKAKVFSYIDRVVFWKLAHWLARKYRTGIASLMRWWCKSPKPGQSKTWVLFGKTNH
                     GKLSGEILYRLVGQGKKLFRWRLPEGNPYLRTETRNTYTSRFTEVAMAFASI"
     gene            2385..2489
                     /locus_tag="RHX21_004605"
                     /pseudo
     CDS             2385..2489
                     /locus_tag="RHX21_004605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001423761.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            2732..3808
                     /locus_tag="RHX21_004606"
     CDS             2732..3808
                     /locus_tag="RHX21_004606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HDV1989681.1"
                     /translation="MVDKVTEAAVVGGVDTHKDLHVAAVVDQNNKVLGTQYFSTTRQG
                     YRQMLAWMTSFGTLKRIGVECTGTYGSGLLRYFQNAGLEVLEVTAPDRMERRKRGKSD
                     TIDAECAAHAAFSGIRTVTPKTRDGMIESLRVLKTCRKTAISARRVALQIIHSNIISA
                     PDELREQLRNMTRMQLIRPLGSWRPDASEYRNVTNVYRISLKSLARRYLELHDEIADL
                     DVMIAAIVDELAPELIKRNAIGYESASQLLITAGDNPQRLRSESGFAALCGVSPVPVS
                     SGKTNRYRLNRGGDRAANSALHIIAIGRLRTDAKTKEYVARRVAEGHTKMEAIRCLKR
                     YISREVYTLLRNQNRRINSIPITA"
     gene            3825..4112
                     /locus_tag="RHX21_004607"
                     /pseudo
     CDS             3825..4112
                     /locus_tag="RHX21_004607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611483.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
     gene            complement(4598..4831)
                     /gene="papI"
                     /locus_tag="RHX21_004608"
     CDS             complement(4598..4831)
                     /gene="papI"
                     /locus_tag="RHX21_004608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major pilus subunit operon transcriptional
                     regulator PapI"
                     /protein_id="HDV1989682.1"
                     /translation="MSEYMKNEILEFLNRHNGGKTAEIAEALAVTDYQARYYLLLLEK
                     EGVVQRSPLRRGMATYWFLKGEMQAGQNCSSTT"
BASE COUNT         1306 a         1199 c         1346 g         1249 t
ORIGIN      
        1 gtgacctata gtgtgcccgg agttcagggc gggcatggat gcttaaatga accgcgagtc
       61 tgtctggaat attgaaccgg taactcacga tgagaaaccc aacaatccca ccgggtgtga
      121 cggtggagaa cctgagcggc agtgacctgc ggcatgcccg cagggtgatg taacccgctg
      181 acaacgggga ttgaggcgag atcactaagc cgagatgatc ctcaaggtta agtactgaaa
      241 ggctgaagaa catgaacccg ttaatccgcc tctgtgggtt gaaaacgtca ccacggccta
      301 cgtgatctga caggccgtgc aggaggaact ggcagtgata cgtaagcact gccggtcgaa
      361 ggtgttttga catgtatgcg aaacaccggg gcagcagcgt ctatcacgct tgcgttgctg
      421 acttctgcca acttgcggca agcaaggata aagagtgcga cgggcagcct cctcagtatg
      481 cctgagtcca ggcaggtaaa ccggggaagg tcagcgacgg atgttaaggg ggcatggctc
      541 cgatgacgcg ctggctggcg gagcttccgt agtagtccgc gatggggaaa gcccattaca
      601 tggcgaaggg aagcagtttg aatgtgtttg cgacgtgaat taactgacct aacgaggtga
      661 agacctttga taatcagcga aatgcaacgc aagcttgcca catgggcagt caccgatccg
      721 tccctacgga ttcaacggct gctgcgtctg ataacacaac cagaatggct ggctgaagcg
      781 gcgcggatca cgctttcatc aaagggggcc catacccccg gcgttgatgg cgtgaacaaa
      841 acaatgctac aggccagact agctgttgag ctgcaaatcc tcagggatga attactctca
      901 ggccactacc agcccttgcc cgccagacgg gtttacatcc ctaaaagcaa cggcaaactg
      961 cgaccactgg gtatccccgc gttgcgggat cgtattgttc agcgggccat gctgatggcg
     1021 atggagccga tatgggagag tgattttcat acgctctcat atggcttccg gcctgagcgc
     1081 agtgtccacc acgctatccg cacggtgaaa ttacagctca cagactgtgg tgaaacccgg
     1141 ggacgctggg tgattgaagg cgacctgtcc agttacttcg acaccgtaca tcatcgactg
     1201 ctgatgaagg ctgtacgccg caggatcagt gacgcacgtt tcatgactct gctgtggaaa
     1261 accatcaagg cgggacatat cgatgtcggt ctctttcggg cggccagtga aggtgtgcca
     1321 cagggcggtg ttatatcgcc gctattatcg aacatcatgc tgaatgagtt cgatcaatac
     1381 ctgcatgagc gctacctgag cgggaaagcc agaaaagatc ggtggtactg gaataacagt
     1441 atccaacggg gccgaagtac ggcggtcaga gaaaactggc agtggaaacc cgcggtggcg
     1501 tactgccgct atgccgatga ttttgtcctc atcgtcaaag gcaccaaagc acaggcggaa
     1561 gccatcaggg aggagtgtcg gggtgtgctc gaaggcagtc tgaaactcag gctgaacatg
     1621 gataagacta aaatcaccca tgttaatgac ggctttatct ttctggggca caggatcatt
     1681 cgcaaacgca gtcgttatgg cgagatgcga gtggtctcaa cgatcccgca ggagaaagcc
     1741 agaaacttcg ccgcatcgct gacagcactg ttatcaggca actacagtga aagcaaagtc
     1801 gatatggctg aacaactcaa ccgaaaactg aaaggctggg ccatgttcta tcagttcgtt
     1861 gattttaagg ccaaagtctt cagttatatc gaccgtgtcg tgttctggaa gctggctcac
     1921 tggctggccc gcaaataccg tacaggtatc gcttccctga tgaggtggtg gtgtaaatca
     1981 ccgaaaccgg gtcagagcaa aacgtgggtt ttatttggta aaaccaatca cggcaagctc
     2041 agcggcgaaa tactgtaccg gttggtgggg caaggcaaga agctgttccg ctggcggcta
     2101 cccgaaggta atccctatct gaggacggag accagaaaca cgtatacatc gcgctttaca
     2161 gaagtggcaa tggcgttcgc cagcatttaa atggagagcc ggatgcgctg aaaggtgcac
     2221 gtccggttcg gggaggagag gcagggaaat agtccgacta cgccctgcct cttactctac
     2281 tctggacggg taagcgctgg gcgtacctcg ccgttgttct caacctgttc gcaagaaaac
     2341 cagtgggctg ggccatgtcg ttctcgccgg acagcaggct caccatgaaa gcgctggaaa
     2401 tggcatggga aacccgtggt aagcccggcg gggtgatgtt ccacagcgat agtaataatg
     2461 ccgatgtcag tctttaccac cacttagttt gccgtttaac cagattggtg tgattactga
     2521 tgcagtgaag accttcccgc atcctgactc acacagcgat cgaccttttg tgtcctgccc
     2581 tggacccgtc ggttgccgga agcgccttca tgcgaggcat ctcctcaccg atgcgcgtga
     2641 ctcaagaagg gcctgacggc ttgtctcgtt actgtcctgt ccgggttatc tgtctggaga
     2701 ttcaactctg tttcctcaca ggagctccgt cattgttgat aaagttaccg aagctgccgt
     2761 tgtgggtggc gtggatacac ataaagattt gcacgttgcc gctgtcgtag atcagaacaa
     2821 taaagtcctt gggactcagt atttctccac aacacgacaa ggttaccggc agatgctggc
     2881 atggatgacc tcgtttggga cattaaaacg aattggtgtt gagtgcacag gtacctatgg
     2941 ttccggtttg cttcgttatt ttcagaacgc cgggttagaa gttcttgagg tgactgctcc
     3001 agaccggatg gagcgacgca aacggggtaa aagtgacaca attgatgctg aatgtgccgc
     3061 tcatgcagca ttctcaggca tcaggacagt tactcccaaa acgcgtgatg gcatgattga
     3121 gtccctgcgg gtattaaaaa cttgccgaaa aacagcaata tcagcccgca gagtcgctct
     3181 ccagattatc cattcaaata ttatctctgc cccggatgaa ttacgtgaac agctcagaaa
     3241 tatgacgcgc atgcagctca tcaggcccct gggttcctgg agacctgatg ccagtgaata
     3301 ccgcaatgta accaacgttt atcgcatttc attaaagtcc cttgcccgac gctatctcga
     3361 gttacatgac gaaatcgctg atctggatgt catgattgcg gcaattgtcg acgagttggc
     3421 acctgagctg attaaacgta atgctatcgg atacgaaagc gcttcacagt tgctgatcac
     3481 tgccggagac aatcctcaac ggttaagatc agaatcagga tttgcggcac tgtgtggtgt
     3541 cagcccggtc cccgtttctt ctggaaaaac gaaccgttac cgacttaatc gtggtggaga
     3601 tcgtgctgca aatagtgcac ttcacatcat cgccatcgga cgcttacgaa ctgacgcaaa
     3661 aacaaaggaa tatgtcgcca ggcgtgtagc cgaaggacat acaaaaatgg aagcgatacg
     3721 ctgtctaaag cgatatatct cccgcgaagt ttacacgtta ctgcgcaatc aaaacaggcg
     3781 gatcaacagt atcccgataa cagcttgact cttagaaggg cgtccagggc agtcattata
     3841 cgagcaggca gttccggcag ttattgtggc gataccagat cagtcagagt atgagccggc
     3901 gcggaaattg ctgggataac agcccaatgg aacgcttctt cagaagtctg aagaacgaat
     3961 ggataccggt ggtgggttac gtaagcttca gcgaggcagc tcacgccata acggattata
     4021 tcgttggata ttacagcgca ctaagaccgc acgaatataa cggtgggtta cccccaaacg
     4081 aatcggaaaa tcgatactgg aaaaaactct aactcggtgg ccagtttttg ttgaccactt
     4141 cagatgcgga cggtcaaaga tcgtggagtt ggattttata aatctgtctc cagtagtaga
     4201 tgaactgaat acaaagttgc cagagagtgg tctgtcaggc agggaatcag aaattggata
     4261 ttattgactg gtacattgtg tcgggctgtg tacgttctcc ccgcagacag tctcagttcg
     4321 tagaatctat aaattactgc tactgatgct gccggggaaa ggcgtaacga aaaaacagcc
     4381 tccgttaccg gacagcaagg aggctgaatg gagtttacag gatttgcttt tttataatgt
     4441 ctggccatgc agtaaaaccg gacaggtttt attatcatgt gaggtattct gacataaaat
     4501 gctggatttt tattttgtga cgaatgctgc aaaattgaat ctgcactctg atgtaacttt
     4561 tatctgtttc agtgaagcat gcccacaaat tgagttatta agttgtggaa gaacagtttt
     4621 gtcccgcctg catctctcct ttcaaaaacc agtatgttgc catgcctcgc cttaatggag
     4681 agcgctgaac cacaccttct ttttccagta ataacaggta atagcgggcc tggtaatccg
     4741 ttaccgccag cgcctctgca atttctgccg ttttccctcc attatgcctg ttcagaaatt
     4801 ccagtatttc attcttcata tattcactca tctcactgta acaaagtttc ttcgaataat
     4861 aaaaatcatg ctttctgtta tcaacggaaa ggtattttta ttctctgtgt ttgctttatt
     4921 tgtgaaattt agtgaatttg ctttttgttg gctttatttg atgtgtatca catttcgtgc
     4981 gttatttttc tgtgaaaaga aagtccgtaa aaatgcattt agacgatctt ttatgctgta
     5041 aattcaattt accatgatgt ttttatctga gtgcattctt tttgttgttg ctttattcta
//
LOCUS       DAPGUL010000212         4936 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.216, whole genome shotgun sequence.
ACCESSION   DAPGUL010000212 DAPGUL010000000
VERSION     DAPGUL010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4936)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4936)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4936
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.216"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            34..786
                     /locus_tag="RHX21_004609"
     CDS             34..786
                     /locus_tag="RHX21_004609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000591154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDV1989683.1"
                     /translation="MIRIYKASKGQLKHREIFDEIKKKIDNGEWKEGKAIPTERELAE
                     HFLSSRTTIRKAIESLKQRGYLHSVHGQGTFTLPARSRENHLLHSFTDDIKARGGVPA
                     QNILEIGYIPLSDIIRKNLELDIHVHTVFCIKRIRYMGSTPLGIQTSWLALNDGQEIT
                     LEELLATGSLYILLEEKLAIKPLEATEIISARLPSPLERQLLELTADDVVLSCTRVTL
                     SVERKPMEYVEMVYPASRYSYKARITKDSFSV"
     gene            800..1876
                     /locus_tag="RHX21_004610"
     CDS             800..1876
                     /locus_tag="RHX21_004610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HDV1989684.1"
                     /translation="MNKIEQAVIYNKILGSLACAGMGDALGAATELYSIDEIKTQWGG
                     FLNAFVSPPADTFAGSLNGVAGLITDDSSQMYVFSEGLIEAGFDNFTNNDWLACLLRW
                     ADMQPYANYKGPTTEQIVKALKEGRPTNTIGRIGTSSRQAPNVGTTNGAGMRVAPAGL
                     IWPGKKEKACRLALITCLPSHDTNIAIASACAIAAATSQAMLPEASLTSLLDAAIWGA
                     NYGERLAKQYARCVAGPSIAMRIQLAADIARRANDLESCLREMEGLVGNSVAAHESIP
                     AAIGLLLYCKGEPWETIHACANIGNDTDSIATMAGAIAGAWRGFDALPEDKYAFFRAV
                     NNKDFDVEAIASGLTLLAVQAQEK"
     gene            1876..2874
                     /locus_tag="RHX21_004611"
     CDS             1876..2874
                     /locus_tag="RHX21_004611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDV1989685.1"
                     /translation="MNMPARAPVMPLAQTREEINATAAALRHLAAIWGECFSSVQLDK
                     RAVERVCIVGSGDSWTVALCAAAWLGKYTHLFCSALQTWDFLQTDLTRYQKETLIIIL
                     SASGRPSLTVDALSHAVCSNAQVLGVTNCPGTPFCAITENMLYTWANKQGIPTQSSSV
                     TLYTLLRLAQNLCPGLTPLQIEEDLEGKFSQINQHWQQKKRHFYQQKEITFLGSGLSW
                     GLAISGSNLLSCGPQIRATAFPLEEFYHSLRLHQAGVGQHYFLLPATSREYPFYIATQ
                     KAIVEQGATAELISFIPDASESNNLFLVMQWLYEMCWHLSCDYVDAGGQRVSHREK"
     gene            2879..3793
                     /locus_tag="RHX21_004612"
     CDS             2879..3793
                     /locus_tag="RHX21_004612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase family protein"
                     /protein_id="HDV1989686.1"
                     /translation="MKKFDVAALGSGNIDIFLSIPSLPTRGGKVVGTRLGEQAGGTVA
                     NSACAMGQLGLNVVSVSCVGNDHSASIILDGFKKYHVNCDFVQVIPELIANTAIIFID
                     ELGEKTLVYSPGSDHEWDKEKALQAIAQSRYYYTMPADIEKFRMLAEYSRSQMTKVVV
                     DIEPHIIATPEHLARILHLADIAIFNYDGFIRGYAAEPDFTLLHDIQDEYQLEAVVVT
                     LDVRGVIAVKGNEQVKIGSYTIPIIDTTGAGDTFNGAFVYSLIKNMPLIEALKFASAT
                     AAINITALGARGHLATPSEVNLFLSQHD"
     gene            3823..4936
                     /locus_tag="RHX21_004613"
                     /pseudo
     CDS             3823..4936
                     /locus_tag="RHX21_004613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702796.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="esterase-like activity of phytase family
                     protein"
BASE COUNT         1433 a         1050 c         1131 g         1322 t
ORIGIN      
        1 gttggtatca accacttgaa atgaggcttt gtcatgataa gaatttataa agccagtaaa
       61 ggtcagctaa agcatcgtga aatttttgat gaaataaaga aaaaaattga taacggtgaa
      121 tggaaagaag gcaaagctat accaacagaa agagaactgg ctgaacattt tttaagcagc
      181 agaacaacaa ttcggaaagc aatagaaagt ttgaaacaac gcggatacct gcatagtgtc
      241 cacgggcaag gaacatttac attaccggct cgcagtcggg aaaatcattt attacatagt
      301 tttactgatg acattaaggc tcgtggtggc gtaccggcac agaatattct tgaaataggt
      361 tatattcctc tcagtgatat tatcagaaaa aatctcgaac ttgatatcca tgtccatacc
      421 gttttctgta taaaacgcat tcgctatatg ggaagtacgc cgctgggtat tcagacatca
      481 tggcttgcgt taaatgacgg acaagaaata actctggaag agctgctggc gacgggttcg
      541 ctctatattt tactggaaga aaaactcgct attaaacctt tagaagcaac ggagattatc
      601 tctgcccggc ttccctcgcc ccttgagcgt caattactgg aactgactgc cgatgacgtc
      661 gtattaagtt gtacccgcgt cacgttatcc gtggaacgta aaccaatgga gtatgtagag
      721 atggtttatc ccgcaagtcg gtactcctac aaagcacgaa ttacaaaaga cagttttagc
      781 gtgtaacaga gagaatattg tgaacaaaat agaacaagcc gtaatttata acaaaatatt
      841 aggttcttta gcctgcgcag gtatgggcga tgcattaggc gcagcgactg aactctacag
      901 cattgatgaa ataaaaactc aatggggagg ttttttaaat gcctttgttt ctcctcctgc
      961 cgataccttt gctggctcat taaatggtgt tgcaggactt atcaccgacg attccagcca
     1021 aatgtatgtg ttttcagaag ggttaattga ggctggattt gataacttca ccaataatga
     1081 ctggttagct tgtcttctgc gttgggccga tatgcagccc tacgcaaatt ataaaggccc
     1141 cacaacagaa caaatcgtca aggcactaaa agaaggtaga ccaacaaaca ccattgggcg
     1201 tattggaaca tcttctcgtc aggcccccaa tgtcggcacc acgaatggcg caggaatgcg
     1261 tgtagccccg gcaggattga tctggcctgg caagaaagaa aaagcgtgtc gcctggcgtt
     1321 aataacttgc ctaccttcac atgacaccaa tattgcgatt gccagcgctt gcgccatcgc
     1381 tgcagcgaca tcgcaggcta tgttaccaga agcctcgctc acatcattac tggatgccgc
     1441 aatctgggga gcgaattacg gcgaacgcct ggccaaacaa tatgcacgat gtgtagcagg
     1501 gccatctatc gccatgcgca tccaacttgc agcggacatc gccagacgtg ccaatgatct
     1561 ggagtcttgt ctgcgagaaa tggaaggttt ggttggtaac tctgttgccg cccatgaatc
     1621 cattcctgcg gcaatcggtc tattgctgta ctgcaaagga gaaccctggg aaaccatcca
     1681 tgcctgcgcc aatattggca atgacaccga tagcatcgct acgatggcag gcgcaattgc
     1741 aggggcatgg cgcggttttg atgcgctccc tgaagataaa tatgcctttt tccgcgccgt
     1801 aaataataaa gatttcgatg ttgaagcgat cgcatcgggt ctgacattgc ttgcagtaca
     1861 ggcacaggag aaataatgaa catgccagcc cgtgctcctg ttatgccatt agcgcaaact
     1921 cgtgaggaaa taaatgcaac ggcggcagcg ctacgccatt tggcagctat ctggggtgaa
     1981 tgtttttcat ctgttcagct cgataaacgt gctgttgaac gcgtctgtat agtgggatcg
     2041 ggcgactcct ggacggtggc actatgtgcc gccgcctggc tggggaaata cacacatctg
     2101 ttttgttccg cattgcaaac gtgggatttt cttcagactg atttaacccg ttatcagaaa
     2161 gaaacgttga tcattattct cagcgcaagt ggcagaccat cactgaccgt tgacgccctt
     2221 agccacgcag tatgctcaaa cgcgcaagtg ctgggtgtga cgaattgccc tggaacacca
     2281 ttttgcgcaa taacagaaaa catgctctat acatgggcga ataagcaggg tattccaacg
     2341 caaagtagta gcgtcacact ttataccctc ctgcgcttag cgcaaaactt atgtccaggc
     2401 ttaacaccac tgcaaattga agaggattta gaagggaaat ttagccagat taatcagcac
     2461 tggcagcaaa agaagcgcca tttttaccaa caaaaagaga taacgtttct ggggagtggc
     2521 ttaagttggg gactagcaat atcggggagc aatttacttt cttgcggccc acagattcgt
     2581 gcgacagcct ttccactgga agaattttat cattcattac gcttacatca ggctggtgtc
     2641 ggtcagcatt attttttact gccagctaca tcccgcgagt acccatttta cattgcaacc
     2701 caaaaagcaa ttgttgaaca gggagcgaca gcagaattaa tcagttttat acctgatgcc
     2761 agtgagtcca acaatttatt tctggtcatg cagtggttat atgaaatgtg ctggcattta
     2821 agttgtgatt atgtcgacgc aggcgggcaa cgcgttagcc atagggagaa ataagactat
     2881 gaagaaattt gatgtcgccg ctttaggcag tggaaatata gatatttttt tatctatccc
     2941 gtcactcccc actcgtggcg gtaaagtggt cgggacacgt ctgggtgaac aagctggcgg
     3001 cacagtcgcc aacagtgcct gtgcgatggg acaactgggt ctcaatgtgg tatctgtttc
     3061 atgtgtgggc aatgatcatt cagcctcgat cattcttgat ggatttaaaa aatatcatgt
     3121 aaattgtgat ttcgttcagg taattccgga attgattgcc aataccgcga ttatctttat
     3181 tgatgaatta ggtgaaaaaa cgttggttta ctcgcctggt agtgatcatg agtgggataa
     3241 agaaaaagcc ctgcaggcaa ttgcgcaaag ccgttattat tatacgatgc cagcagatat
     3301 cgagaaattt cgtatgctgg ccgaatattc ccgtagccag atgacaaaag ttgtcgttga
     3361 tattgagcct catatcattg caacacctga acaccttgcc agaattttac accttgctga
     3421 tattgcgata tttaattatg acggttttat tcgtggctat gcagcagagc cagattttac
     3481 acttctgcat gatatacaag acgagtatca acttgaggct gtcgtggtta cgctggatgt
     3541 taggggagta attgcagtca aaggcaatga gcaagtaaaa ataggtagct atacaattcc
     3601 cattattgat accactggcg ctggagatac ttttaatggt gcatttgttt atagcttaat
     3661 aaaaaacatg cccttaattg aagcactaaa atttgcttct gccactgcag caataaatat
     3721 tactgcatta ggtgccagag gtcatctggc gacaccatcg gaagttaatc tttttctttc
     3781 acaacacgac taaaatcaga tacatacaca aaggtaaata tcatgaaaat aagacatgcc
     3841 gctatttttc tggcattacc gctgttatgc acaacagcgc aggcaaacag ttttcttcat
     3901 tatgctggtg agttcaactt ccggacggga gaaaaacaga acaatgttac aatcgcgggg
     3961 ctatcagcca tcacatttga tgcaaaaaaa atattttcta tgctattaac gatagcagaa
     4021 acaataataa agaaggagat gccagtcttt atacactaaa aatacaggta tcatccaggg
     4081 gcattgagca agtgaatttt ctcaaccagc gtccactgct tgatgcaaaa cagcagcctt
     4141 tcgtgaccaa tacggtggat gccgaaggtc tggccctgac acacaatggt aagtcattac
     4201 tctggagttc ggagttaggt gctccactgc gtctgagcac tctcgatggc gtaatggaga
     4261 aagattttac gtctttattt cctgctcgat ttaatattag ttctgacaaa gagagcagca
     4321 atggtattcg cagcggcaac gcctgggagg gcctgacagt tacaccagat ggaaaatcac
     4381 tttttatcgc cgttgaaagc agccttaaac aggatgggcc tattgcaagt ccaataaatt
     4441 caggtacatc acgcttactg caattttcta tagatgcaga cggtcgacct tcaaagcaat
     4501 tgcatgaata tctctatatt actgatcctg ttccgcaagt gagtaagttc ggtattaatg
     4561 ataatggcgt atccgaggtc ctggcgctga atgatcacca attgttggtc atcgaacgtt
     4621 ccggcagaaa cgtcagtgct gggttcaatg actgggatta ctctgtcaga gtttatatgg
     4681 tcgatttaac tgctgccagc gatatcaagg atattgacag tctgcaagat tggtccaata
     4741 aatccacgtt acaacccgtc agtaaaaaat tattaattga ttttgctgat tacacttcct
     4801 ctgcggattg tattgaaggg gtaaccttcg gtcctctgat tgatgggcat acatcgttaa
     4861 tatttgtatc tgataataat ttccagcccc atcaacagac gaaattttat ctattcattg
     4921 ataaggaaaa caaact
//
LOCUS       DAPGUL010000213         4919 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.217, whole genome shotgun sequence.
ACCESSION   DAPGUL010000213 DAPGUL010000000
VERSION     DAPGUL010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4919
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.217"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(271..684)
                     /locus_tag="RHX21_004614"
                     /pseudo
     CDS             complement(271..684)
                     /locus_tag="RHX21_004614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015377870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
     gene            682..939
                     /locus_tag="RHX21_004615"
                     /pseudo
     CDS             682..939
                     /locus_tag="RHX21_004615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611787.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            complement(1173..2030)
                     /gene="sitD"
                     /locus_tag="RHX21_004616"
     CDS             complement(1173..2030)
                     /gene="sitD"
                     /locus_tag="RHX21_004616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter permease subunit
                     SitD"
                     /protein_id="HDV1989687.1"
                     /translation="MMALLLEPLQFTFMSHALLISLVVSIPCALLSVFLVLKSWALMG
                     DAMSHAVFPGIVLAWILGLPLATGAFVAGVFCAVATGYLKDNSRIKQDTVMGIVFSGM
                     FAAGLILYIAVKPDVHLDHILFGDMLGITIGDIIQTVIIAGLVTLVISVKWRDFLLFS
                     FDYQQAQASGLHTRWLHYGLLCMVSLTIVATLKAVGIILSISLLIAPGAIAVLLTQRF
                     HIALLLATGISILVSMTGVWLSFFIDSAPAPTIVVLFAVMFIMTFTVTSINARTKENA
                     EPRDLLSSD"
     gene            complement(2027..2884)
                     /gene="sitC"
                     /locus_tag="RHX21_004617"
     CDS             complement(2027..2884)
                     /gene="sitC"
                     /locus_tag="RHX21_004617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter permease subunit
                     SitC"
                     /protein_id="HDV1989688.1"
                     /translation="MNVLLEPFSYEYMLNAMWVSAMVGGLCAFLSCYLMLKGWSLIGD
                     ALSHSIVPGVAGAYMLGLPFSLGAFFSGGLAAGSMLFLNQLTRLKEDAIIGLIFSSFF
                     GLGLFMVSLNPTSVNIQTIVLGNILAIDPADILQLTIIGILSIIVLFFKWKDLMVTFF
                     DENHARAIGLHPGRLKILFFTLLSVSTVAALQTVGAFLVICLVVTPGATAWLLTDRFP
                     RLLMIAVTIGSVTSFLGAWVSYFLDGATGGIIVVAQTLLFLLAFVFAPTHGLLANRRR
                     AHKALEDRS"
     gene            complement(2881..3708)
                     /gene="sitB"
                     /locus_tag="RHX21_004618"
     CDS             complement(2881..3708)
                     /gene="sitB"
                     /locus_tag="RHX21_004618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter ATP-binding
                     protein SitB"
                     /protein_id="HDV1989689.1"
                     /translation="MMQSAGIVVNDVTVTWRNGHTALRDASFTVPGGSIAALVGVNGS
                     GKSTLFKAIMGFVRLTSGKISVLGIPTRQALQKNLVAYVPQSEEVDWSFPVLVEDVVM
                     MGRYGHMGMLRIAKKRDRQIVTDALERVDMVDFRHRQIGELSGGQKKRVFLARAIAQQ
                     GDVILLDEPFTGVDVKTEAKIISLLRELRAEGKTMLVSTHNLGSVTTFCDYTVMVKGT
                     VLASGPTDTTFTAENLELAFSGVLRHVTLNGSEESIITDDERPFVAHRPSAVQREER"
     gene            complement(3708..4622)
                     /gene="sitA"
                     /locus_tag="RHX21_004619"
     CDS             complement(3708..4622)
                     /gene="sitA"
                     /locus_tag="RHX21_004619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter substrate-binding
                     protein SitA"
                     /protein_id="HDV1989690.1"
                     /translation="MLSIKKVTMLLGCLVLTCSIAFQASAAEKFKVITTFTIIADMAK
                     NVAGDAAEVSSITKPGAEIHEYQPTPGDIKRAQGAQLILANGMNLELWFQRFYQHLNG
                     VPEVIVSSGVTPVGITEGPYEGKPNPHAWMSPDNALIYVDNIRDAFIKYDPINAQTYQ
                     RNADTYKAKITQTLAPLRKQIAELPENQRWMVTSEGAFSYLARDLGLKELYLWPINAD
                     QQGTPQQVRKVVDIVKKNHIPAVFSESTISDKPARQVARETGAHYGGVLYVDSLSTEN
                     GPVPTYIDLLKVTTSTLVQGIKAGKREK"
BASE COUNT         1358 a         1232 c         1147 g         1182 t
ORIGIN      
        1 tttatatcct ttgactacat gcaagataag ggaaggttct atttattgac attaataccc
       61 tcgacaattg ctgagcagaa gcccccacga caagtgacag aatgacaaca tctacagtgg
      121 ggagcgtttt atcgatgaac aagcaaccaa gaagtaacac ggcataggtg acgacaatgc
      181 cagtaagcat agaaataaca aaaacgtgag ctttcatcat tcctccagaa taaccccgac
      241 gtgtaagcct gggggattgg cacaataatg tcatttaaag gcagactttc cggcaaattg
      301 cgccgatgaa cccagttcat cctcaattct cataagctgg ttatattttt caatacgctc
      361 accccggcat ggagctcccg ttttgagatg acctgcgcgc attgcaactg tcatatcggc
      421 gataaagctg tccactgtct caccactgcg gtgtgagata aaggtgcccc agttgttgtc
      481 atggcaaagt tgtaccgcat caaaggtttc actcagggaa ccaatctggt tgagtttaat
      541 caatgctgaa ttggcaaggt tttcgtcaat gccgcgctga atatacttta cgttggtcac
      601 aaacagatcg tcgccaacca attctatctg ctctcccaat gcaccatgca ggattttcca
      661 tccagcccag tcatcttcag ctaccgttaa gggcaggaag atcaactagg tgctctgggg
      721 ctggtgacca atgcggttgt gctgtgaaac acactttaca tgcaggaggc gttgtcacat
      781 cttcgcaaat cgggagaaac tcctgaggag tagcatccgg caagattatc gctgctgata
      841 catagccata taaatatgct ggggcattat acgtcttcgt taccggaaga tattcttaag
      901 ggtgagttaa gatcattaaa cttcaataca aacaattaat taaactctta gcgtggtttt
      961 ttacatcact ggccctcgcc ccccaatttt ctctatgttt tgccactact tccctcattt
     1021 tactgcgctg tttgctatcc ctgagaatcg acattacttg ctatccagtc cgcagcaact
     1081 ctctggcaac aaaacttatc agaatcataa gtctgtgcat tattcgttca agcgcatcgc
     1141 caataagcgg atgttgctgg ccgagtgttc tgctaatcgg atgataacaa atcccgtggt
     1201 tcggcatttt cctttgtgcg tgcgttgatg ctggtaacgg taaacgtcat gatgaacatg
     1261 accgcgaata agacaacaat tgtcggagct ggcgcgctgt cgataaaaaa ggacagccag
     1321 acaccagtca ttgagaccaa tatcgatatg ccagtcgcca gcaggagcgc aatatgaaag
     1381 cgttgtgtca ggagtaccgc aatggcacca ggcgcaatga gaagagaaat agagagaatg
     1441 atacctaccg ctttcagcgt cgccacaatg gtcagggaga ccatgcacag cagcccataa
     1501 tgcagccatc tcgtatgcaa accgcttgcc tgcgcctgtt gataatcaaa gctgaacagc
     1561 aaaaaatccc gccattttac gctaataaca agtgtaacca gtccggcaat aatcaccgtc
     1621 tggattatat cgccgatggt tatcccgagc atgtcgccga aaagaatatg atcaagatgt
     1681 acgtctggtt tgactgcaat atacaagatc agacctgcgg caaacatgcc agaaaaaaca
     1741 atccccatca ctgtatcttg cttgattcgg ctgttgtctt tcaggtatcc cgtcgccacc
     1801 gcacagaata ctccggcgac gaatgcccct gtagccagag gtaaccccag aatccaggca
     1861 agcacgatgc caggaaaaac cgcatgactc atcgcgtcac ccatcagtgc ccaacttttc
     1921 aggaccagaa agaccgacag cagcgcacag ggtatggaaa ctaccagtga aatcagcagt
     1981 gcgtgactca taaaggtgaa ctgcagtggc tccagtaata atgccatcat gagcgatcct
     2041 ccagcgcttt atgcgcacgc cgacgatttg ccaaaagccc atgggtgggc gcaaagacaa
     2101 atgctaaaag aaacagcagt gtctgcgcca ccacgatgat tccacctgtc gcgccgtcca
     2161 gaaagtaact gacccacgcg ccgaggaaac tggtcacact gccaatagtt acagcaatca
     2221 tgagcaggcg gggaaaacga tcggttaaca accatgctgt tgcaccggga gtcaccacca
     2281 gacagatcac cagaaaggca ccaaccgttt gcagcgccgc aacggtcgaa accgacagca
     2341 gggtgaagaa gaggattttt aatctgcccg gatgcaatcc aatagcacgg gcgtgattct
     2401 cgtcgaaaaa ggtcaccata agatctttcc atttgaaaaa aagcacgatg atcgagagaa
     2461 tgccaatgat agtgagttgc aggatatccg ccggatcgat tgccagaata ttgcccagga
     2521 cgatggtctg aatgttcacg gatgtcgggt tcaatgacac cataaacagc cccaggccaa
     2581 aaaaggacga gaagatcagg ccgatgatgg catcttcttt taagcgagtg agttggttaa
     2641 gaaacagcat gctgcccgct gccagtccgc cggaaaagaa ggctcccaga gaaaacggaa
     2701 gccccagcat atatgccccc gcaacacccg ggacaataga gtgcgacagc gcatcgccaa
     2761 tcagcgacca gccttttagc atcagatagc atgacaggaa agcgcagaga ccgccgacca
     2821 tcgccgagac ccacatcgca ttgagcatat attcatagct gaagggttcc agtagcacgt
     2881 tcatctttct tccctctgca ccgctgacgg tcgatgtgcc acaaaagggc gttcatcgtc
     2941 agtaataatg ctttcttccg agccgttaag tgtgacatgg cgcagtacgc cgctaaaagc
     3001 cagctccagg ttctcggctg taaaagtggt gtctgtcggc ccgcttgcca ggacggtgcc
     3061 tttgaccatg accgtataat cgcaaaatgt cgtgacggat ccgagattgt gcgttgagac
     3121 aagcatcgtt ttgccttccg cgcgtaactc cctcaacagg ctgatgattt tcgcttcggt
     3181 tttcacatca acgccggtaa aaggttcatc cagcaggatc acatcaccct gctgtgcaat
     3241 cgctctcgcc agaaagacgc gtttcttttg tccaccggaa agctcgccga tttgtcgatg
     3301 gcgaaaatcc accatatcga cacgttccag cgcatcggtg acaatctgac gatccctctt
     3361 tttggcgata cgcaacatac ccatatgccc atagcggccc atcatcacca catcttccac
     3421 cagtacagga aatgaccagt caacctcttc tgactgaggg acgtaggcaa ccaggttttt
     3481 ctgtagcgcc tgtcgtgtgg gaatacccag aacagatatc ttcccgctgg tcagacgcac
     3541 aaatcccata atcgctttaa acaacgtcga ttttccggaa ccgtttaccc caaccagagc
     3601 ggcaatagat ccgcctggta ctgtgaagga tgcatcgcgc agtgctgtgt gcccgttacg
     3661 ccaggtgaca gtaacatcat taacgacaat gcctgcagat tgcatcatta tttctccctt
     3721 tttccggctt taattccctg taccagcgta ctggtagtaa ccttcagaag gtcgatatac
     3781 gtaggtaccg ggccgttttc tgtgctcagg gaatcgacat agagcacacc accgtagtgc
     3841 gcgccggttt cacgcgcaac ctgacgcgct ggtttatcgg aaatcgtact ctcgctaaag
     3901 actgccggga tatgattttt cttaactata tcaacaacct tacgtacctg ctgcggtgtt
     3961 ccttgttgat cggcattaat cggccacaga taaagctctt ttagccccaa atcgcgtgcg
     4021 agataagaaa aagccccttc actggtgacc atccatcgct gattctcagg gagttccgca
     4081 atctgcttac gcaggggggc aagggtttgg gtaatcttgg ctttataagt atcggcatta
     4141 cgttggtagg tttgtgcatt tatcggatcg tattttataa acgcatcacg aatattatcg
     4201 acgtaaatca gagcattatc tggcgacatc caggcatggg ggttaggttt gccctcatag
     4261 ggcccttcgg tgatccctac tggcgtcaca cccgaagaga caattacttc tggaacccca
     4321 ttgagatgct ggtaaaagcg ttggaaccac aattccagat tcataccatt ggcgagaatc
     4381 agttgtgccc cctgcgcacg tttaatatcg ccaggggtag gctgatactc atgaatttct
     4441 gcaccaggct tggttatgga tgagacttct gcagcatctc cagccacgtt tttggccata
     4501 tctgcgatga tggtaaaagt tgtaatgacc ttgaattttt cagctgcact cgcctgaaat
     4561 gctatcgagc aggtgaggac taggcacccc aagagcatgg ttactttttt tattgagagc
     4621 atgatttagt acctatagtg agcaaaatta gaataaacat agcaactact atgttttata
     4681 gcagaagcta taaaatgtaa ataattatca ttagcgatta taagatccca acacagggat
     4741 taggttattt cctgctgacg atgtggtatt gaggataaaa gttgggcagc gctttggctt
     4801 taaaatgaac ttgttcagga cgattggtaa tggcaaagca aaaataatgt aggttattgg
     4861 caagttctct aggacgcagg agagcatgaa aaacccaggg gcagtcacta aatgaaggg
//
LOCUS       DAPGUL010000214         4871 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.218, whole genome shotgun sequence.
ACCESSION   DAPGUL010000214 DAPGUL010000000
VERSION     DAPGUL010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4871
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.218"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(67..828)
                     /gene="kduD"
                     /locus_tag="RHX21_004620"
     CDS             complement(67..828)
                     /gene="kduD"
                     /locus_tag="RHX21_004620"
                     /EC_number="1.1.1.127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
                     KduD"
                     /protein_id="HDV1989691.1"
                     /translation="MILSAFSLEGKVAVVTGCDTGLGQGMALGLAQAGCDIVGINIVE
                     PTETIKQVTALGRRFLSLTADLRKIDGIPALLDRAVAEFGHIDILVNNAGLIRREDAL
                     EFSEKDWDDVMNLNIKSVFFMSQAAAKHFIAQGNGGKIINIASMLSFQGGIRVPSYTA
                     SKSGVMGVTRLMANEWAKHNINVNAIAPGYMATNNTQQLRADEQRSAEILDRIPAGRW
                     GLPSDLMGPVVFLASSASDYVNGYTIAVDGGWLAR"
     gene            complement(858..1694)
                     /gene="kduI"
                     /locus_tag="RHX21_004621"
     CDS             complement(858..1694)
                     /gene="kduI"
                     /locus_tag="RHX21_004621"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HDV1989692.1"
                     /translation="MDVRQSIHSAHAKTLDTQGLRNEFLVEKVFVADEYTMVYSHIDR
                     IIVGGIMPITKTVSVGGEVGKQLGVSYFLERRELGVINIGGAGTITVDGQCYEIGHRD
                     ALYVGKGAKEVVFASIDTGTPAKFYYNCAPAHTTYPTKKVTPDEVSPVTLGDNLTSNR
                     RTINKYFVPDVLETCQLSMGLTELAPGNLWNTMPCHTHERRMEVYFYFNMDDDACVFH
                     MMGQPQETRHIVMHNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVKD
                     LR"
     gene            complement(1981..3162)
                     /locus_tag="RHX21_004622"
     CDS             complement(1981..3162)
                     /locus_tag="RHX21_004622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417321.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HDV1989693.1"
                     /translation="MKDVVIVGALRTPIGCFRGALAGHSAVELGSLVVKALIERTGVP
                     AYAVDEVILGQVLTAGAGQNPARQSAIKGGLPNSVSAITINDVCGSGLKALHLATQAI
                     QCGEADIVIAGGQENMSRAPHVLTDSRTGAQLGNSQLVDSLVHDGLWDAFNDYHIGVT
                     AENLAREYGISRQLQDAYALSSQQKARAAIDAGRFKDEIVPVMTQSNGQTLVVDTDEQ
                     PRTDASAEGLARLNPSFDSLGSVTAGNASSINDGAAAVMMMSEAKARALNLPVLARIR
                     AFASVGVDPALMGIAPVYATRRCLERVGWQLADVDLIEANEAFAAQALSVGKMLEWDE
                     RRVNVNGGAIALGHPIGASGCRILVSLVHEMVKRNARKGLATLCIGGGQGVALTIERD
                     E"
     gene            3417..4646
                     /locus_tag="RHX21_004623"
     CDS             3417..4646
                     /locus_tag="RHX21_004623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease"
                     /protein_id="HDV1989694.1"
                     /translation="MSNIWSKEETLWSFALYGTAVGAGTLFLPIQLGSAGAVVLFITA
                     LVAWPLTYWPHKALCQFILSSKTSAGEGITGAVTHYYGKKIGNLITTLYFIAFFVVVL
                     IYAVAITNSLTEQLAKHMVIDLRIRMLVSLGVVLILNLIFLMGRHATIRVMGFLVFPL
                     IAYFLFLSIYLVGSWQPDLLTTQVEFNQNTLHQIWISIPVMVFAFSHTPIISTFAIDR
                     REKYGEHAMDKCKKIMKVAYLIICISVLFFVFSCLLSIPPSYIEAAKEEGVTILSALS
                     MLPNAPAWLSISGIIVAVVAMSKSFLGTYFGVIEGATEVVKTTLQQVGVKKSRAFNRA
                     LSIMLVSLITFIVCCINPNAISMIYAISGPLIAMILFIMPTLSTYLIPALKPWRSIGN
                     LITLIVGILCVSVMFFS"
BASE COUNT         1273 a         1236 c         1064 g         1298 t
ORIGIN      
        1 ttatgatgat ctacagatat aaaaaaccct gccatgcggc agggtcataa aagtaagaag
       61 aatgaattaa cgcgccagcc aaccgccatc cacggcaatg gtataaccat tcacataatc
      121 tgaagcgctg gaggcaagga acactaccgg ccccatcagg tcactcggca gtccccaacg
      181 gccagctgga atgcggtcga ggatttccgc gctacgttgt tcatctgccc gtagttgttg
      241 agtattgttg gtcgccatgt aacccggggc tatcgcatta acattaatgt tgtgtttagc
      301 ccattcgttc gccatcaatc gcgtcacacc catcacgccg ctttttgatg cggtataaga
      361 aggcacacgg atcccgccct ggaaggagag cattgacgcg atattgataa tcttgccgcc
      421 attgccttgc gcgataaagt gtttcgccgc tgcctgagac atgaagaata cgctcttgat
      481 attcaggttc atgacatcgt cccagtcttt ttcgctgaac tcgagagcgt cttcgcggcg
      541 aatcaatccg gcgttattca ccaggatatc aatatgacca aactccgcta ccgcgcgatc
      601 cagcagtgct ggaataccat caatctttcg cagatcggcg gtcaggctta aaaaacgacg
      661 ccccagcgcc gtgacctgct tgatggtttc agtcggttca acgatgttaa tgccaacaat
      721 gtcacagccc gcttgcgcca gccccaacgc catcccctgg cccagcccag tatcacagcc
      781 agtgacgacc gcaactttac cttcgagaga aaatgcactt aaaatcataa caatacctta
      841 ttcgtttatg cccacaacta gcgcaaatct ttaacggcca catggtccat atcatcaaag
      901 acctggtttt caccgaccat gccccagata aaggtataag ctttggttcc gacgccggaa
      961 tgaatcgacc agctcgggga gatcaccgcc tgctcgttat gcatcacaat atgacgcgtt
     1021 tcttgcggct gccccatcat gtggaaaacg caggcgtcat catccatatt gaaatagaaa
     1081 taaacttcca tccggcgctc gtgggtgtga cacggcatgg tgttccacaa gttacccgga
     1141 gccagctccg tcagccccat actcaattgg caggtttcca gtacatccgg gacaaaatat
     1201 ttgttaatcg tgcgacggtt actggtgagg ttatcgccta acgtgactgg agatacttcg
     1261 tccggtgtga cttttttggt gggatacgtc gtatgcgcgg gtgcgcaatt gtaataaaac
     1321 ttcgccggag tgccggtatc aatactggca aagacaactt cttttgcacc tttaccaaca
     1381 tacagggcgt cgcggtgacc gatttcatag cattggccat cgacagtaat cgtaccggca
     1441 ccgccaatat tgataacacc taactcgcga cgttcaagga aatagcttac gccgagttgt
     1501 ttaccaactt ccccgccaac ggaaaccgtt ttagttatcg gcataatgcc gccaacaata
     1561 attcggtcaa tgtggctgta aaccatggtg tactcatcgg cgacaaatac cttttcaacc
     1621 aaaaattcat tgcgcagccc ttgggtatcc agcgtttttg cgtgcgcact gtggatgctc
     1681 tgtcttacgt ccacatcaac ctccgataat cagtgaagcg tgaaaataga aaacgatagt
     1741 gaaacactgt ttcgttttct ctataaaggg atgatatgcc catgggctag ggttttcaat
     1801 taaaaataaa acaatgtttc atttttaagt taaggattaa aaaaagtgca gtgtcgatca
     1861 cgaatatgtc atgagaatgg aaaaatgagg gagcccagaa aatgtatgtc gacttgccag
     1921 ccatcattat tcaacagatt aatgacggca gatatttatc ggtaaggagg aaatgcagag
     1981 ctattcgtca cgttcaatgg tcaatgccac gccctggccc ccgccgatac aaagcgttgc
     2041 cagtcctttg cgggcattac gtttcaccat ttcatgaacc agagaaacca ggattcggca
     2101 accggaagcg cctatcgggt gaccaagtgc gatcgcacca ccattgacat tgacccgacg
     2161 ctcatcccac tcaagcatct tgccaaccga aagcgcctgt gcagcaaacg cttcattagc
     2221 ctcgataaga tcgacatcag ccaactgcca gcctacacgc tccaggcaac ggcgggtcgc
     2281 atacaccggc gcaattccca tcaatgccgg atctacacca acgctggcaa atgcgcgaat
     2341 gcgggccagc acgggtaaat tcaacgctcg tgctttggct tcgctcatca tcattaccgc
     2401 agctgcgcca tcgtttatgg atgatgcatt acccgctgtc acagaaccga gactatcaaa
     2461 tgaaggattt aaacgggcta aaccttctgc actggcgtca gtgcgtggct gttcatcggt
     2521 atcaacaacc aacgtctgac cgttactttg ggtcattacc gggacgatct catctttaaa
     2581 tcgtccggcg tcaatcgccg ctcgcgcttt ttgttgcgag ctaagtgcgt aagcatcctg
     2641 caattgacgg ctgatgccat attcgcgagc cagattttcg gcggtgacac caatatgata
     2701 atcattgaag gcatcccata acccatcatg cacaagactg tcaaccagct ggctattgcc
     2761 aagctgtgca ccggtgcggc tatcagtcag aacatgtggt gcgcggctca tgttttcctg
     2821 gccaccggcg atgacaatat cagcctcgcc acactgtatc gcctgagtag ccagatgcag
     2881 tgctttaagt ccggaaccgc agacgtcatt aatcgtgatt gcagaaacgc tattaggcag
     2941 accaccttta atagccgatt gccttgccgg attctgccct gcccctgcag tcaacacctg
     3001 accaagaatt acttcatcca ccgcatatgc aggaacgccg gtacgttcta ttaacgcttt
     3061 cacgaccaga ctaccaagtt ccacggcgga atgacccgct aacgcaccgc gaaagcagcc
     3121 gataggtgtc cgtaacgccc cgacaatcac aacgtctttc atcacaacct cgcaccaatt
     3181 aacagtgcaa tagtaaatga ttgttaatta cagttatctt aattgtttaa aaaaagtgat
     3241 ttttatcaca aaggaaatat gcctgagcag tagtcagagt cataactggc acgtaaggtt
     3301 tgcaaccact aacccaccaa tagaggggta gatagggcgt taatctccca tacttaacct
     3361 ggtttatggt aaattgccct ccattttgtt taatttgtag atgatacgtt cagataatgt
     3421 ctaatatttg gtctaaagaa gaaactctgt ggagtttcgc gctctacggc acagccgttg
     3481 gtgcaggcac gctcttcctt cctattcagt taggttcggc aggggctgtg gtcctgttta
     3541 ttactgctct ggtcgcctgg cctttaacat attggccaca taaagcctta tgccagttca
     3601 tcctctcatc gaaaacatca gcaggtgaag ggataacggg cgcagtaaca cactactatg
     3661 gcaagaagat tggtaatctg attaccacgc tgtacttcat cgcctttttt gtcgtcgtgt
     3721 tgatatatgc agtggcaatt accaactcac ttacggaaca gctggcaaag catatggtta
     3781 ttgatcttcg catccgtatg ttggtgagtc tgggtgttgt attaatcctg aatctcattt
     3841 ttctgatggg acgccatgca accattcggg taatgggttt tttggtattc ccattgattg
     3901 cctatttctt atttctttcc atttaccttg tcggtagttg gcaacctgat ctattaacga
     3961 cccaggtaga gttcaatcag aatacccttc accagatatg gatatcgatt cccgtgatgg
     4021 ttttcgcctt tagccatacg cccattattt ctacgtttgc catagacaga cgtgaaaaat
     4081 atggcgaaca cgctatggat aaatgcaaaa aaattatgaa agtcgcttat ctcatcatct
     4141 gcataagtgt actgttcttt gtctttagct gcctgctttc tattccacct tcgtatattg
     4201 aagcggctaa agaagaaggg gtcaccattt tatcggcgct ttctatgctg ccgaacgccc
     4261 cagcatggct gtcaatttcc gggattattg tcgcagtagt tgcgatgtcg aaatcattcc
     4321 tgggtacgta ctttggcgtt attgaaggtg ccacggaggt cgtcaaaaca acactacagc
     4381 aggttggtgt aaagaaaagt cgtgcattta accgcgcact atcaattatg ttggtatcgc
     4441 tgatcacctt cattgtttgt tgcattaacc cgaacgcgat ttcgatgatt tacgcgatca
     4501 gcggcccgct cattgccatg atacttttca tcatgcctac gttgtcaacg tatctgatcc
     4561 cggcgcttaa accctggcgt tccatcggaa atctgattac gctgatcgtg ggtatcctgt
     4621 gcgtatcggt aatgttcttt agctgatatc cattgtgaat ggttcaaaat tgctacaatt
     4681 ttgaaccatt ccagttttca taatgttcat tcgttattat tccgcactat cacttccctc
     4741 atcatatcct agtattatca gttagttaaa cacacaaaga gatctgaaca tcttaaataa
     4801 gactatttaa gatgcataac ttagattcgc aagatatctt ctggtcattc aaaaacaatt
     4861 tgcgatatag a
//
LOCUS       DAPGUL010000215         4864 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.219, whole genome shotgun sequence.
ACCESSION   DAPGUL010000215 DAPGUL010000000
VERSION     DAPGUL010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4864
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.219"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..633)
                     /gene="betT"
                     /locus_tag="RHX21_004624"
     CDS             complement(<1..633)
                     /gene="betT"
                     /locus_tag="RHX21_004624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline BCCT transporter BetT"
                     /protein_id="HDV1989695.1"
                     /translation="MTDLSHSREKDKINPVVFYTSAGLILLFSLTTILFRDFSALWIG
                     RTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSVKLGPEQSKPEFSLLSWAAMLFA
                     AGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMA
                     LGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLG"
     gene            762..1349
                     /gene="betI"
                     /locus_tag="RHX21_004625"
     CDS             762..1349
                     /gene="betI"
                     /locus_tag="RHX21_004625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308386.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator BetI"
                     /protein_id="HDV1989696.1"
                     /translation="MPKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTG
                     IISHYFRDKNGLLEATMRDITSQLRDAVLNRLHALPQGSAEQRLQAIVGGNFDETQVS
                     SAAMKAWLAFWASSMHQPMLYRLQQVSSRRLLSNLVSEFRRELPRQQAQEAGYGLAAL
                     IDGLWLRAALSGKPLDKPLAHSLTRHFITQHLPTD"
     gene            1363..2835
                     /gene="betB"
                     /locus_tag="RHX21_004626"
     CDS             1363..2835
                     /gene="betB"
                     /locus_tag="RHX21_004626"
                     /EC_number="1.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine-aldehyde dehydrogenase"
                     /protein_id="HDV1989697.1"
                     /translation="MSRMAEQQLYIHGGYTSATSGRTFETINPANGNVLATVQAAGRE
                     DVDRAVKSAQQGQKIWAAMTAMERSRILRRAVDILRERNDELAKLETLDTGKAYSETS
                     TVDIVTGADVLEYYAGLIPALEGSQIPLRETSFVYTRREPLGVVAGIGAWNYPIQIAL
                     WKSAPALAAGNAMIFKPSEVTPLTALKLAEIYSEAGLPDGVFNVLPGVGAETGQYLTE
                     HPGIAKVSFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIVFDDADLDLAADIAMM
                     ANFFSSGQVCTNGTRVFVPAKCKAAFEQKILARVERIRAGDVFDPQTNFGPLVSFPHR
                     DNVLRYIAKGKEEGARVLCGGDVLKGDGFDNGAWVAPTVFTDCSDDMTIVREEIFGPV
                     MSLLTYESEDEVIRRANDTDYGLAAGIVTADLNRAHRVIHQLEAGICWINTWGESPAE
                     MPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMAKFQSIF"
     gene            2849..4519
                     /gene="betA"
                     /locus_tag="RHX21_004627"
     CDS             2849..4519
                     /gene="betA"
                     /locus_tag="RHX21_004627"
                     /EC_number="1.1.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline dehydrogenase"
                     /protein_id="HDV1989698.1"
                     /translation="MQFDYIIIGAGSAGNVLATRLTEDPNTSVLLLEAGGPDYRFDFR
                     TQMPAALAFPLQGKRYNWAYETEPEPFMNNRRMECGRGKGLGGSSLINGMCYIRGNAL
                     DLDNWAQEPGLENWSYLDCLPYYRKAETRDVGENDYHGGDGPVSVTTSKPGVNPLFEA
                     MIEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPQGRRASTARGYLDQAKSRPNLTIRT
                     HAMTDHIIFDGKRAVGVEWLEGDSTIPTRATANKEVLLCAGAIASPQILQRSGVGNAE
                     LLAEFDIPLVHELPGVGENLQDHLEMYLQYECKEPVSLYPALQWWNQPKIGAEWLFGG
                     TGVGASNHFEAGGFIRSREEFAWPNIQYHFLPVAINYNGSNAVKEHGFQCHVGSMRSP
                     SRGHVRIKSRDPHQHPAILFNYMSHEQDWQEFRDAIRITREIMHQPALDQYRGREISP
                     GTECQTDEQLDEFVRNHAETAFHPCGTCKMGYDEMSVVDGEGRVHGLEGLRVVDASIM
                     PQIITGNLNATTIMIGEKIADMIRGQEALPRSTAGYFVANGMPVRAKK"
BASE COUNT         1172 a         1324 c         1376 g          992 t
ORIGIN      
        1 accgagcgta gtggcaatac cgaagatggt gccgatcacc gctgcaatat ccactgagtg
       61 ccctatcggc ccgttaatcc gtttaccgaa gatcgggtac agcgccgagc ggatggtgag
      121 cggcaaatta taacgatagc taaagtatcc gagcgccatg cccatcagcg catacatcga
      181 ccagccggtt aagccgtagt gaaacagcgt ccagaccatc gcctgacgcg cggcctcaat
      241 cgtctgtccc gcgccttccg gcggctgcat atactgcgtt accggttcgg ctacggagaa
      301 gaacatcagg tcgataccga tcccggcagc aaacagcatc gccgcccaac tcagcaggct
      361 gaattccggt ttggattgtt ctggcccgag cttcaccgaa ccaaaacgcg aacaagcgat
      421 acagaccaca aagacaatat agagcgttgc cgccagtaga tagtaccaac cgaaggtttt
      481 agaaacccag tccagcgtgc ggccaatcca cagggccgag aagtcgcgaa acaggatcgt
      541 tgtcagggaa aacaacaaaa tcagtccggc ggaggtgtaa aacaccaccg gattgatttt
      601 gtccttttcc ctgctgtgtg aaaggtctgt catccagtat ccccactgtt attgttacca
      661 tttaaaatca aattcgtaac aattaagaca cattttatat tgaacgtcca atcaataacc
      721 gctttaatag ataaacaacg ctgatgaatg gagtggcgaa aatgcccaaa ttggggatgc
      781 agtcgatccg gcgcagacaa ctgatcgacg ccacactgga agcaataaat gaagtgggca
      841 tgcacgatgc aacgatcgcg cagatcgccc gccgtgcagg cgtttctacg gggatcatca
      901 gccactattt cagggacaaa aatggtctgc tggaagcaac catgcgcgat atcaccagtc
      961 agctgcgtga cgcggttttg aatcgattac atgcacttcc gcagggcagt gcagagcagc
     1021 gattacaggc gattgttggc ggaaacttcg atgaaacgca ggtgagcagt gcggcgatga
     1081 aagcctggct ggcgttctgg gccagcagta tgcatcagcc gatgctctat cgtttacagc
     1141 aggtcagtag ccgccgctta ttgtcgaatc tggtgagcga atttcgccgc gagttaccgc
     1201 gccaacaggc acaggaagcg ggctacggcc ttgccgcgct gattgacgga ttatggctgc
     1261 gcgcggcact gagcggcaaa ccgctggata aacctctcgc acactcgctg acccgtcact
     1321 ttattactca gcatttaccc accgattaac cgaggagacg tgatgtcccg aatggcagaa
     1381 cagcagcttt atatacatgg tggttatacc tccgccacca gcggtcgcac cttcgagacc
     1441 attaacccgg ccaacggtaa cgtgctggcg accgtgcagg ccgccgggcg tgaggatgtc
     1501 gatcgcgccg tgaagagtgc ccaacagggg caaaaaatct gggcggcgat gaccgctatg
     1561 gagcgctcgc gtattctgcg tcgggccgtt gatattctgc gtgaacgcaa tgacgaactc
     1621 gcaaaactgg aaaccctcga caccggaaaa gcatattcgg aaacctcaac cgtcgatatc
     1681 gttaccggtg cggacgtgct ggagtactac gccgggctga tcccggcgct ggaaggcagc
     1741 cagatcccgt tgcgtgaaac gtcctttgtg tatacccgcc gcgaaccgct gggcgtagtg
     1801 gcagggattg gcgcatggaa ctacccgatc cagattgccc tgtggaaatc cgccccggcg
     1861 ctggcggcag gcaacgcaat gattttcaaa ccgagcgaag ttaccccgct taccgcgtta
     1921 aagctggctg aaatttacag cgaagcgggc ctgccggacg gcgtatttaa cgtgttgccg
     1981 ggcgtgggcg cggagaccgg gcaatatctg accgagcatc cgggcattgc caaagtgtca
     2041 tttaccggcg gtgtcgccag cggcaaaaaa gtgatggcta actcggcggc ctcttccctg
     2101 aaagaagtga ccatggaact gggcggtaaa tcaccgctga tcgttttcga tgatgcggat
     2161 ctcgatctcg ccgccgatat cgccatgatg gcaaacttct tcagctccgg tcaggtgtgt
     2221 accaatggca cccgcgtctt cgttccggcg aaatgcaaag ccgcatttga gcagaaaatt
     2281 ctggcgcgcg ttgagcgcat tcgcgcgggc gacgttttcg atccgcaaac taacttcggc
     2341 ccgctggtca gcttcccgca tcgcgataac gtgctgcgct atatcgccaa aggcaaagag
     2401 gaaggcgcgc gcgtactgtg cggcggcgat gtactgaaag gcgatggctt cgataacggc
     2461 gcatgggttg caccgacagt gttcaccgat tgcagcgacg atatgaccat cgtgcgtgaa
     2521 gagatcttcg ggccagtgat gtcgcttctc acttatgaat ctgaggacga agtgattcgc
     2581 cgcgccaatg ataccgacta cggcctggcg gcgggcatcg tgacggcgga cctgaaccgc
     2641 gcgcatcgcg tcattcatca gctggaagcg ggtatttgct ggatcaacac ctggggcgaa
     2701 tccccggcag agatgcccgt tggcggctac aaacactccg gcattggtcg cgagaacggc
     2761 gtgatgacgc tccagagtta cacccaggtg aagtccatcc aggttgagat ggctaaattc
     2821 cagtccatat tctaaccagg aggtttattt gcaatttgac tacatcatta ttggtgccgg
     2881 ctcagccggc aacgttctcg ctacccgtct gactgaagat ccgaatacct ccgtgctgct
     2941 gcttgaagcg ggcggcccgg actatcgctt tgacttccgc acccagatgc ccgcagcgct
     3001 ggcgttccca ctacagggca aacgctacaa ctgggcctat gaaacagagc ctgaaccgtt
     3061 tatgaataac cgccgcatgg agtgcggacg cggtaaaggc ctgggtggat cgtcgctgat
     3121 caacggcatg tgctacatcc gtggcaatgc gctggatctc gataactggg cgcaagaacc
     3181 cggtctggag aactggagtt atctcgactg cctgccctac taccgcaagg ccgagactcg
     3241 cgatgtgggc gagaacgact accacggtgg cgatggcccg gtgagcgtca ccacctccaa
     3301 acccggcgtc aatccgctgt ttgaagcgat gattgaagcg ggcgtgcagg caggctaccc
     3361 gcgcacggac gatctcaacg gctatcagca ggaaggtttt ggcccgatgg atcgcaccgt
     3421 cacgccgcag ggccgtcgcg ccagtaccgc gcgcggttat ctcgatcagg ccaaatcgcg
     3481 ccctaacctg accattcgta ctcacgctat gaccgatcac atcatttttg acggcaaacg
     3541 cgcggtgggc gtcgaatggc tggaaggcga cagcaccatc ccaacccgcg caacggccaa
     3601 caaagaagtg ctgttatgtg caggcgcgat tgcctcaccg cagatcctgc aacgctccgg
     3661 cgtcggcaac gctgaactgc tggcggagtt tgatattccg ctggtgcatg aattacccgg
     3721 cgtcggcgaa aatcttcagg atcatctgga gatgtatctg caatatgagt gcaaagaacc
     3781 ggtttccctc taccctgcac tgcagtggtg gaaccaaccg aaaatcggtg cggagtggct
     3841 gtttggcggc actggcgttg gtgccagcaa ccactttgaa gcaggtggat ttattcgcag
     3901 ccgtgaggaa tttgcgtggc cgaatattca gtaccatttc ctgccagtag cgattaacta
     3961 taacggctcg aatgcagtga aagagcacgg tttccagtgc cacgtcggct caatgcgctc
     4021 gccaagccgt gggcatgtgc ggattaaatc ccgcgacccg caccagcatc cggcgattct
     4081 gtttaactac atgtcgcacg agcaggactg gcaggagttc cgcgacgcaa ttcgcatcac
     4141 ccgcgagatc atgcatcaac ccgcgctgga tcagtatcgt ggccgcgaaa tcagccccgg
     4201 cacggaatgt cagacggatg aacagctcga tgagttcgtg cgtaaccacg ccgaaaccgc
     4261 cttccatccg tgcggtacct gcaaaatggg ttacgacgag atgtccgtgg ttgacggcga
     4321 aggccgcgta cacgggttag aaggcctgcg tgtggtggat gcgtcgatta tgccgcagat
     4381 tatcaccggg aatttgaacg ccacgacaat tatgattggc gagaaaatag cggatatgat
     4441 tcgtggacag gaagcgctgc cgaggagcac ggcgggatat tttgtggcaa atgggatgcc
     4501 ggtgagagcg aaaaaatgag tcgtgatttg aactgactca agaaccgatc tgattgagag
     4561 ttaccgttcc aggtatgggg acagaatcgt tatataaaac ataggggtaa ctctcatgct
     4621 tcatagtgac aacctcgcca gcaaattcta agcggactcg ttcaatctgg ctgatgaagg
     4681 tgctatgaat gcactgataa accgcaggtg aaatgccact cagcttaaga attacgccgc
     4741 tagtgttcct ggctatggtg acttgttcac tcccgctcac ggttagcata tacgaaaagg
     4801 gttcttgaaa cgaggacaaa aataagtcag accaaaacaa cgtggagctt taaacacgat
     4861 tcgt
//
LOCUS       DAPGUL010000216         4783 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.220, whole genome shotgun sequence.
ACCESSION   DAPGUL010000216 DAPGUL010000000
VERSION     DAPGUL010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4783
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.220"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            112..1086
                     /gene="hemB"
                     /locus_tag="RHX21_004628"
     CDS             112..1086
                     /gene="hemB"
                     /locus_tag="RHX21_004628"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308450.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HDV1989699.1"
                     /translation="MTDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDY
                     KAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETGSDAWREDGLVARM
                     SRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLENLGKQAVVAAAAGAD
                     FIAPSAAMDGQVQAIRQALDAAGFKDTAIMSYSTKFASSFYGPFREAAGSALKGDRKS
                     YQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDIVRELRERTELPIGAYQVSGEY
                     AMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKKILR"
     gene            complement(1192..2043)
                     /gene="tauD"
                     /locus_tag="RHX21_004629"
     CDS             complement(1192..2043)
                     /gene="tauD"
                     /locus_tag="RHX21_004629"
                     /EC_number="1.14.11.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine dioxygenase"
                     /protein_id="HDV1989700.1"
                     /translation="MSERLSITPLGPYIGAQISGADLTRPLSDNQFEQLYHAVLRHQV
                     VFLRDQTITPQQQRALAQRFGELHIHPVYPHAEGVDEIIVLDTHNDNPPDNDNWHTDV
                     TFIETPPAGAILAAKELPSTGGDTLWTSGIAAYEALSVPFRQLLSGLRAEHDFRKSFP
                     EYKYRKTEEEHQRWREAVAKNPPLLHPVVRTHPVSGKQALFVNEGFTTRIVDVSEKES
                     EALLGFLFAHITKPEFQVRWRWQPNDIAIWDNRVTQHYANADYLPQRRIMHRATILGD
                     KPFYRAG"
     gene            complement(2040..2867)
                     /gene="tauC"
                     /locus_tag="RHX21_004630"
     CDS             complement(2040..2867)
                     /gene="tauC"
                     /locus_tag="RHX21_004630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter permease TauC"
                     /protein_id="HDV1989701.1"
                     /translation="MSVLINEKLHSRRLKWRWPLSRQVTLSIGTLAVLLTVWWTVAAL
                     QLISPLFLPPPQQVLAKLLTIAGPQGFMDATLWQHLAASLTRIVLALLAAVVIGIPVG
                     IAMGLSPTVRGILDPVIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS
                     ALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAE
                     LIAATRGLGFMVQSAGEFLATDVVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ"
     gene            complement(2864..3631)
                     /gene="tauB"
                     /locus_tag="RHX21_004631"
     CDS             complement(2864..3631)
                     /gene="tauB"
                     /locus_tag="RHX21_004631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter ATP-binding subunit"
                     /protein_id="HDV1989702.1"
                     /translation="MLQISHLYADYGGKPVLEDINLTLESGELLVVLGPSGCGKTTLL
                     NLIAGFVPYQHGSIQLAGKRIEGPGAERGVVFQNEGLLPWRNVQDNVAFGLQLAGIEK
                     MQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALD
                     AFTRDQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSSGPGRVLERLPLNFA
                     RRFVAGESSRSIKSDPQFIAMREYVLSRVFEQREAFS"
     gene            complement(3644..4606)
                     /gene="tauA"
                     /locus_tag="RHX21_004632"
     CDS             complement(3644..4606)
                     /gene="tauA"
                     /locus_tag="RHX21_004632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414899.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter substrate-binding
                     protein"
                     /protein_id="HDV1989703.1"
                     /translation="MAISSRNTLLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNT
                     FAKESGATVDWRKFDSGASIVRALASGDVQIGNLGSSPLAVAASQQVPIEVFLLASKL
                     GNSEALVVKKTISKPEDLIGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPA
                     IIAAWQRGDIDGAYVWAPAVNALEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHP
                     EVVKAFAKSAIDAQQPYIANPDAWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTPQ
                     QQTVELTGPVNKAIIDTAQFLKEQGKVPAVANDYSQYVTSRFVQ"
BASE COUNT         1091 a         1393 c         1230 g         1069 t
ORIGIN      
        1 ctggcctctc ttccattctc ttcttgtcaa catcgcgaca actttcgtaa aacatcccta
       61 ccctgcttca ggtatactat gcccctcgat tccacaaaca tcaggcagac catgacagac
      121 ttaatccaac gccctcgtcg cctgcgcaaa tctcctgcgc tgcgcgctat gtttgaagag
      181 acaacactta gccttaacga cctggtgttg ccgatctttg ttgaagaaga aattgacgac
      241 tacaaagccg ttgaagccat gccaggcgtg atgcgcattc cagagaaaca tctggcacgc
      301 gaaattgaac gcatcgccaa cgccggtatc cgttccgtaa tgacttttgg catctctcac
      361 cataccgatg aaaccggcag cgacgcctgg cgggaagatg gactggtggc gcgtatgtcg
      421 cgcatctgca agcagactgt gccagaaatg atcgtcatgt cagacacttg tttctgtgaa
      481 tacacttctc acggtcactg cggtgtgctg tgcgagcatg gcgtcgacaa cgacgcgact
      541 ctggaaaatt taggcaagca agccgtggtt gcagctgctg caggcgcaga cttcatcgcc
      601 ccttccgccg cgatggacgg ccaggtacag gcgattcgtc aggcgctgga cgctgcaggc
      661 tttaaagata cggcgattat gtcgtattcg accaagttcg cctcttcctt ttatggcccg
      721 ttccgtgaag ctgccggaag cgcattaaaa ggcgaccgca aaagctatca gatgaaccca
      781 atgaaccgtc gcgaggcgat tcgtgagtca ctgctggatg aagcccaggg cgcagactgc
      841 ctgatggtta aacctgctgg agcatacctc gacatcgtgc gtgagctgcg tgaacgtact
      901 gaattgccga ttggcgcgta tcaggtgagc ggtgagtacg cgatgattaa gttcgccgcg
      961 ctggcgggtg ctatagatga agagaaagtc gtgctcgaaa gcttaggttc aattaagcgt
     1021 gcgggtgcgg atctgatttt cagctacttt gcgctggatt tggctgagaa gaagattctg
     1081 cgttaatttt tttcctctca gaaaggggga gttaacctgt tgaaagtacg gtgaacgccc
     1141 cctcacccta accctctccc caagggggcg agggaaccgt ccgcactcgt atcaccccgc
     1201 ccgataaaac ggtttatccc caaggatcgt cgcccgatgc ataatccgcc gctgtggcag
     1261 gtaatcggca ttggcatagt gctgagtcac gcggttatcc caaatcgcaa tatcattcgg
     1321 ttgccagcgc caacgcacct gaaactccgg tttagtgata tgggcgaata aaaagcctaa
     1381 caaggcttcg ctctctttct cgctgacatc gacaattcgc gtagtaaagc cttcattcac
     1441 aaacagcgcc tgtttaccgc tcaccggatg cgttcgcacc accggatgta gcaacggagg
     1501 atttttcgcg accgcctcgc gccagcgttg atgttcctcc tcggttttgc ggtatttgta
     1561 ttccgggaac gatttacgga aatcatgctc cgcacgcagc ccgctcagca gctggcggaa
     1621 gggaacagag agcgcctcat aggccgcaat accgctggtc cagagcgtat caccgccggt
     1681 cgaaggtaac tctttagctg ccagaatcgc ccctgcgggt ggcgtttcaa taaatgtcac
     1741 atcggtatgc cagttgtcgt tatccggcgg attatcgtta tgggtatcca gcacgatgat
     1801 ctcgtcaacc ccttcggcat gagggtaaac agggtgaata tgcagttcgc caaaacgctg
     1861 ggccagcgcg cgttgctgct gcggcgtaat agtttgatcg cgcagaaaca ccacctgatg
     1921 gcgcagcacc gcatggtaaa gctgttcaaa ctgattatcg cttaacgggc gcgtcaggtc
     1981 ggcacccgaa atttgtgcgc cgatatacgg ccccagcggg gtaatgctca gacgttcact
     2041 cattgtactt ctccatgcca gggcgtcaga cggcgctgta acgcgcgcaa acctagttct
     2101 aaaagaaagg cgataatcgc aatcaccgcg attcccgcca gcaccacgtc agtcgcgaga
     2161 aattcacccg ctgactgaac cataaatcct aaaccgcgcg tcgcggcaat cagctccgcc
     2221 gctaccagcg tagaccagcc cacacccaga ccaatgcgta atccggtgag gatttccggc
     2281 agcgcgccgg gcaaaatgac aaaccacagc acctgcgcac ggctggcacc cagcgactgg
     2341 gcggcacgaa tgcgaacctg ctgcgcgctt ttcacccccg ccagcgccga catcgccacc
     2401 ggtgcaaaaa tcgctaaata gatcagtaag atcttcgagg tttcaccaat accaaaccag
     2461 atcaccatca gcggcaaata agccagcggc ggcaccggac gataaagttc gattaccgga
     2521 tccagaatgc cgcgcaccgt cgggcttagc cccatggcga tcccgaccgg aataccgatc
     2581 accaccgccg cgagtagcgc cagcacaatg cgcgtcaggc tggctgccag atgctgccac
     2641 agcgtggcgt ccataaatcc ctgcggtccg gcaatggtga gcagttttgc cagtacttgt
     2701 tgcggcggcg gcaaaaacag cgggctaatc agttgcagcg ccgccaccgt ccaccataca
     2761 gtgagtaaaa ccgctaacgt gccaatgctt aaggtcacct gacgcgagag cggccagcgc
     2821 catttcagcc gccgcgaatg cagtttttca ttaatgagca cactcatgag aacgcctccc
     2881 gttgctcaaa tacgcggctt aaaacatatt cgcgcatggc gatgaattgt ggatcggact
     2941 tgatgctgcg gctcgactct cccgcaacaa agcggcgagc aaagttgagc ggcagccgct
     3001 ccagcacacg gccagggccg gatgaaagca gaaccagttc agtcgccata aacaccgctt
     3061 cttctatatc gtgggtaatc aacagcacct gcttgcccgt ctcctgccag agtttcagca
     3121 gcagagtttg catctggtcg cgggtgaagg cgtccagcgc accaaacggt tcgtcgagta
     3181 ataacagctg gggattcgcc gccagcgcgc gggcaatccc cacccgctga cgttgaccac
     3241 cggaaagctg ccagatatag cgtttttctg cgccttccag ccccactttt ttcagcatct
     3301 ggtgcgcgat ttccagtcgc tgcattttct ctatacctgc caattgcagg ccgaacgcca
     3361 cgttgtcctg tacattgcgc cacggtagta gcccttcatt ctgaaaaacc accccgcgct
     3421 ctgctcccgg tccctcaata cgcttacccg ccagttgaat gctgccatgc tgataaggca
     3481 caaaaccggc aatcagattc agcagggtgg ttttaccgca gccggacggc cccagcacca
     3541 ccagtagctc gccgctttcc agcgtcaggt tgatatcttc cagtaccggt ttgccgccat
     3601 aatcggcgta aagatgagag atttgcagca tctgcgcctc cttttattgc acgaagcgcg
     3661 aggtaacgta ctggctgtaa tcattcgcta cagccgggac cttgccctgc tctttcaaaa
     3721 actgcgcggt gtcgatgatc gctttgttca ccggtccggt cagttctacc gtttgttgct
     3781 gcggcgtcag ataggtattc cccttcacca gccccggaac gtcaccttcc ggcacgccgc
     3841 ttaaacgcgc cagtttgctg atgttttccg gctgtttcag ccacgcgtct gggttagcaa
     3901 tgtacggttg ctgagcatcg atggcgcttt tagcgaacgc tttcacgacc tcaggatgtt
     3961 tctcggcaaa atctttgcgc accacccaga cgtccagcgt tggcgcaccc cactgcccga
     4021 cctgttcaga atcggtcaac accttgccgt ctttttccag ggcgttaacc gccggtgccc
     4081 agacataagc accatcaata tcaccccgct gccatgcggc gataatcgcg ggcggctgca
     4141 ggttcacaat ctccacttgc cctggtttaa tcccccagtg tttcagcgcc gccagcaggc
     4201 tgtagtgggt ggtggagata aacggtacgg caatgcgttt gccaatcaaa tcttcgggtt
     4261 tgctgatagt tttctttacc accagcgctt cggagttacc cagttttgac gccagcaaga
     4321 agacttcaat cggcacctgt tggctggctg caaccgctaa tgggctggaa ccgaggttgc
     4381 cgatttgcac gtcgccagaa gccagcgccc gcacgatgct ggctccgctg tcaaacttac
     4441 gccagtccac ggttgctccg ctttctttag caaaggtgtt gtcggcctga gccactttcg
     4501 ccggttcggc tgaggtttga tacgccacgg tgacgttcac cgcctgtgcc tgaaaagcga
     4561 tgaatgccag tgcggcaaga agtgtgttac gcgatgaaat tgccatgatt gtctgctccc
     4621 ctgtcttgtt atgggagcag tattcaggaa taaaaacatt cattaaaaga attagtcgtt
     4681 atcgcacaga tgattttatt cttagcaaaa aaacggctaa ggaaagatta aatatgcaat
     4741 tactccgttc taacaattgg gaaaattact acacttcatt tta
//
LOCUS       DAPGUL010000217         4750 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.221, whole genome shotgun sequence.
ACCESSION   DAPGUL010000217 DAPGUL010000000
VERSION     DAPGUL010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4750
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.221"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(90..509)
                     /locus_tag="RHX21_004633"
     CDS             complement(90..509)
                     /locus_tag="RHX21_004633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HDV1989704.1"
                     /translation="MKKIQIVCSGIVLVVISSLAQAVELSLNTSDGRSGELKDGTKVA
                     TGRIICRGTYTSFHIWMNSRQMGNIPGHYIILGRHDSHNEMRVRLDGAGWLPSVSDGQ
                     GMVSTGIPEQHTFDVVIDGNQLLGPDEYILSVSGECS"
     gene            complement(525..3113)
                     /locus_tag="RHX21_004634"
     CDS             complement(525..3113)
                     /locus_tag="RHX21_004634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_110996819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus outer membrane usher protein"
                     /protein_id="HDV1989705.1"
                     /translation="MHRNKSSSGLSLYCVKTKITAVALSVMAACTLLYTGNTEARTYS
                     FDASMLKGGGKGVDLTLFEEGAQLPGIYPVDIILNGSRVDSRDMAFRTEKDAEGKTYL
                     KTCLTREMLARYGVMTEEYPELFHGDDGKEAEACAELSVIPQATETYQFASQQLLLSI
                     PQVALRPPLRGIAPEALWDDGIPAFLLNWQANTSRSEYRGYGKSVTDNYWVTLEPGIN
                     LGPWRVRNLTTWNRSSGQPGQWESAYIRAERGINSLRSRLTLGEDYTPSDIFDSVPFR
                     GVMLGADESMVPYNQREFAPVVRGIARTQARIEVRQNGYLIDSRTVAPGAFALTDLPL
                     TGSGGDLQVTVQESDGTAQVFTVPYTTPAIALREGYMKYSIAGGEYRSSDDAVEHSPL
                     GQMSVMYGLPWGLTAFGGAQMSSHYQSAALGLGWSMGRLGAVSVDGIHSRGQQKGRDT
                     ETGETWRLRYNKSFELTNTDLTAARYQYTSSGFHTLSDVLSTFRNDNFRAYSYSGDRS
                     RRTTLRLNQSLGSLGYMSFYGSRDEFRHNRQKQDSFGMSYGTSWKNISWYVNWSRNYS
                     TNAYYQRGHIEDSINLWMNIPLGQWIGGRDNDINVTTQTQRTTGQNTWYETGLNGRAF
                     DRRLYWDVSERIAPGSENNVDSSRLNLRWFGTYGELAGMYSYSSYIRQMSAGISGGMV
                     LHNEGITLGQKGEDTVALVVAPGVNGASVGSLPGVRTDTRGYTLVNHVSPYQENLITL
                     DPTTFPENVEVSQTDTRVVPTKGAVVRAKFITRVGGRALITLSRSDGSRLPFGAVVTE
                     EGKKGQMPGGAGVVGDNGEVYLSGLDETGQLKVQWGRNSSCRANYRLPEEKEATGIFL
                     VRTVCM"
     gene            complement(3282..4049)
                     /locus_tag="RHX21_004635"
     CDS             complement(3282..4049)
                     /locus_tag="RHX21_004635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HDV1989706.1"
                     /translation="MKIRHLAALVGILAGLPASGVMAAGNQESTKTTSKVFSLHLGAT
                     RVIYNLDSSGASLTVMNDLDYPMLVQSEVLAENQKDPAPFVVTPPLFRLDALQSSRLR
                     IVRTGGVFPEDRESLQWLCVKGIPPKHDDRWAEEKGADKKKADKATLQVNLSVSSCVK
                     LFVRPPAVKGPPEDAGGKVEWTKSGNKLKGNNPTPFYINISELSVGGKEVKEHRYISP
                     YSSYEYEIPSGASGKVSWTVITDYGGKSKPFESELKS"
     gene            complement(4127..4471)
                     /locus_tag="RHX21_004636"
     CDS             complement(4127..4471)
                     /locus_tag="RHX21_004636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001323645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin biosynthesis transcription regulatory
                     family protein"
                     /protein_id="HDV1989707.1"
                     /translation="MNSEVCLHLVKERSGILLPGEVSERHFWLLIEISGMHSEKVINA
                     LREHLVMGYTRREACEQHGVSQGYLSGALVRIQHLSQTVNNLLPYYVSGLAMNHEEEG
                     DRSVKRGGDWRV"
BASE COUNT         1249 a         1395 c          896 g         1210 t
ORIGIN      
        1 tatatgcttt tataaaataa catgctattt tagagggcag ccattgacaa ctgaatagtt
       61 actttattag cataaagaaa ttatgaatat tatgagcatt ctccgctaac tgataatata
      121 tattcatcag gcccaagcag ctgatttccg tcaatcacaa catcaaatgt atgctgctca
      181 ggtatcccgg tactgaccat accttgccca tcacttaccg atggcaacca tcctgcgcca
      241 tccagcctaa cccgcatttc attatgactg tcatgtctgc ccagtataat atagtgacca
      301 ggaatatttc ccatttgtct gctattcatc cagatatgaa aacttgtata ggtgcctcgg
      361 cagataatcc ttcctgttgc caccttcgta ccgtctttta actcgccact ccttccatca
      421 ctggtattaa gactcagttc aactgcctgc gccagactgg atataaccac cagtacaata
      481 ccactacata ctatctgtat tttcttcatc agggtactcc ttggtcacat acacacagtg
      541 cgcaccagaa aaataccagt tgcttctttc tcctctggaa gtcgataatt tgcacggcaa
      601 gaactgttac gcccccattg aaccttcaac tgtccggttt catccagtcc gctcaaatac
      661 acttctccat tatcccccac aacccctgcc ccaccaggca tttgaccttt ctttccttcc
      721 tctgtcacca cagctccaaa aggcaggcga gagccgtcac tacgtgacag agttatcagt
      781 gctcttcccc ctactcgagt gataaacttc gcccgaacca cggctccctt tgtaggaaca
      841 acacgagtat ctgtctgtga tacttccaca ttttccggga aagttgtcgg atccagtgta
      901 ataagatttt cttggtatgg agatacatga ttcacaagag tgtaacctct ggtatcggtc
      961 ctaacgccag gcaaactccc aactgaagcg ccattaactc caggtgctac aaccagagca
     1021 accgtatcct ctcctttctg accaagagtg ataccttcat tgtggagcac catacctcct
     1081 gatataccag cactcatctg gcgaatataa ctgctgtaac tgtacatccc cgccaactca
     1141 ccataggtac caaaccacct caaattcagt cggctactgt ctacattatt ttcacttccg
     1201 ggagctatcc gctcactcac atcccaatac aacctacggt caaatgcgcg accattcaaa
     1261 ccggtttcgt accaagtatt ctgccccgta gttctttgcg tttgagttgt aacattaata
     1321 tcgttatctc tacccccaat ccactgcccc agaggaatat tcatccacag attgatacta
     1381 tcctctatat gccctctctg ataatatgca tttgtactat agttacgtga ccaattaacg
     1441 taccacgaaa tattcttcca tgacgttcca tatgacatgc cgaaagaatc ctgcttctgt
     1501 cggttatgac ggaactcatc acggctaccg taaaagctca tataccccag agatcccaga
     1561 gactgattaa ggcgtaatgt tgtccggcga ctcctgtccc cactataact atatgcacga
     1621 aaattatcat ttctaaatgt actcagcaca tcggacaatg tgtggaatcc tgaggacgta
     1681 tactgatatc tcgccgctgt caaatctgta ttcgtaagtt caaatgactt gttgtaacgc
     1741 agacgccatg tctctcccgt ctccgtatcc cgtcccttct gctgaccgcg ggaatgaatg
     1801 ccgtcaaccg acaccgcccc cagtctgccc attgaccatc ccagccccag agccgctgac
     1861 tgataatgcg atgacatctg tgctcccccg aaggccgtca gcccccatgg cagaccatac
     1921 atgacactca tctgccccag cggtgaatgc tcaacagcat catctgaaga acggtactcc
     1981 cccccggcaa tgctgtactt catatatccc tcacgaagcg caatggccgg tgtggtgtaa
     2041 ggcaccgtaa acacctgagc agtaccatca gattcctgta ccgttacctg aaggtctcca
     2101 cctgaccccg tcagcggcag gtccgtcagg gcaaatgcgc ccggggccac cgtccggctg
     2161 tcaatcagat aaccattctg gcgcacctca atcctggcct gggtccgggc aatacctctg
     2221 accaccggcg caaattcacg ctggttataa ggcaccatgc tctcatctgc ccccagcatc
     2281 accccacgga acggcacact gtcaaaaatg tctgaaggcg tgtaatcctc acccagcgtc
     2341 agacgacttc tgagactgtt aatcccccgc tccgcacgaa tataggcact ctcccactgc
     2401 cccggctgac cggatgacct gttccaggtt gtcaggttac gcacccgcca gggaccaaga
     2461 ttaatgcccg gctcaagagt gacccagtaa ttgtcagtaa ccgatttccc gtatccacga
     2521 tattctgaac gactggtatt tgcctgccag ttcagcagaa aagcaggaat accatcatcc
     2581 cataaggcct ccggcgctat ccccctcagt ggcgggcgca gggccacctg aggaatactc
     2641 agcagcaact gctgtgacgc aaactggtat gtttccgtgg cctgtggaat aacggataac
     2701 tcagcacagg cttcagcttc ctttccgtca tccccgtgaa acaactccgg atattcctcc
     2761 gtcatgacac catagcgggc cagcatttcc cgggtcagac aggttttcag ataagtctta
     2821 ccctccgcat ctttctccgt acggaacgcc atgtcccgcg aatccacccg cgaaccgttc
     2881 aggataatat caaccggata gataccgggc agttgggcac cttcttcaaa caacgtcagg
     2941 tccaccccct ttccgccacc tttaagcatg gaagcatcaa aggagtatgt gcgggcctca
     3001 gtattcccgg tgtaaagaag ggtacaggcc gccatcacag agagagcaac cgctgtaatt
     3061 tttgttttta cgcaatataa agataaacct gaagatgact tattcctgtg cattattcac
     3121 acctgagcca cggtttcttt ttatttacat atgccggagg atatacacac gtatttgtgc
     3181 gtttgcacgc ctgttcacac acacttattt caaacacgct cagatattca accgggttaa
     3241 tcaaataagc ccgcctctga cgttaatatt tattccggct ttcagctttt taattccgat
     3301 tcaaacggct tactctttcc gccgtaatcc gtaatcactg tccagctgac ttttcctgat
     3361 gcaccagaag gaatttcata ttcgtaagag gagtacggag aaatataacg atgctcctta
     3421 acctctttcc caccaacgct cagctctgaa atattaatat aaaatggtgt cgggttattc
     3481 cctttcagtt tattacctga ttttgtccac tccacttttc cgcccgcatc ctccggaggc
     3541 cctttaaccg caggcggacg aacaaacagc ttcacacaac tgctgacgga aagatttacc
     3601 tgcagggttg ccttgtcagc tttcttttta tcagcacctt tctcttctgc ccatcggtca
     3661 tcatgctttg gcggaatgcc tttcacacaa agccactgca gactctcacg gtcctcagga
     3721 aaaacacccc cggtacggac aattcgcaaa cggctcgact gaagtgcatc cagacggaaa
     3781 agcggcggcg tcaccacaaa gggggccggg tccttctgat tctctgccag cacctcagac
     3841 tgaaccagca tcggataatc caggtcattc attaccgtca gtgaggcccc cgatgaatcc
     3901 aggttgtaaa tcacccttgt ggcccccaga tgcagggaaa aaacctttga cgtagtcttc
     3961 gtgctttcct ggtttccggc tgccattacg ccggaagccg gcaaccccgc cagtatgcca
     4021 acgagcgctg caagatgtct gattttcatt attttatcct gaaggcaaat aaacctttta
     4081 taaatatgtt aatagcaacc gcccgacagc tgtcaccagt atcccctcag acccgccagt
     4141 caccaccacg ctttactgac cgatcaccct cctcttcatg gttcattgcc aaaccagaaa
     4201 cataataagg aagcagatta ttcaccgtct gactgaggtg ctgaatccga accagcgctc
     4261 ctgataaata cccctgagaa acaccgtgct gctcacaggc ctccctgcgg gtatatccca
     4321 taacaagatg ctccctgagc gcattaatca ctttctcact gtgcatcccg gatatttcaa
     4381 tcaataacca gaaatgcctt tctgatactt ccccgggcag cagaatcccg gaccgctctt
     4441 tcaccagatg caaacaaacc tccgaattca taaccccgtt tactctgaca gggaaacaaa
     4501 ctctcagcat cagcgccgga atgaacaccg gtaatcccct gcctcgccac caacattacc
     4561 atggagttta atgctgtaaa tatgattatt gacgatcttt ttaaccaaat aacaacaatt
     4621 aaacaggtta taacactact ccagtgcaaa aatacagcgc tgaaatccag aaatcatata
     4681 aaatacagat aaaaagatcg ttttttgcat aatttctgat attacataac aacatgaaaa
     4741 tatcttattt
//
LOCUS       DAPGUL010000218         4744 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.222, whole genome shotgun sequence.
ACCESSION   DAPGUL010000218 DAPGUL010000000
VERSION     DAPGUL010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4744
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.222"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            77..1411
                     /gene="garP"
                     /locus_tag="RHX21_004637"
     CDS             77..1411
                     /gene="garP"
                     /locus_tag="RHX21_004637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate/glucarate/glycerate transporter
                     GarP"
                     /protein_id="HDV1989708.1"
                     /translation="MILDTVDEKKKGVHTRYLILLIIFIVTAVNYADRATLSIAGTEV
                     AKELQLSAVSMGYIFSAFGWAYLLMQIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGF
                     VDMFPLAWAGISMFFMRFMLGFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFS
                     LALFSPLLGWLTFAWGWEHVFTVMGVIGFVLTALWIKLIHNPTDHPRMSAEELKFISE
                     NGAVVDMDHKKPGSAAASGPKLHYIKQLLSNRMMLGVFFGQYFINTITWFFLTWFPIY
                     LVQEKGMSILKVGLVASIPALCGFAGGVLGGVFSDYLIKRGLSLTLARKLPIVLGMLL
                     ASTIILCNYTNNTTLVVMLMALAFFGKGFGALGWPVISDTAPKEIVGLCGGVFNVFGN
                     VASIVTPLVIGYLVSELHSFNAALVFVGCSALMAMVCYLFVVGDIKRMELQK"
     gene            1427..2197
                     /gene="garL"
                     /locus_tag="RHX21_004638"
     CDS             1427..2197
                     /gene="garL"
                     /locus_tag="RHX21_004638"
                     /EC_number="4.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxyglucarate aldolase"
                     /protein_id="HDV1989709.1"
                     /translation="MNNDVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWL
                     VLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVET
                     KEEAEQAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDN
                     VDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAP
                     VEADARRYLEWGATFVAVGSDLGVFRSATQKLADTFKK"
     gene            2227..3117
                     /gene="garR"
                     /locus_tag="RHX21_004639"
     CDS             2227..3117
                     /gene="garR"
                     /locus_tag="RHX21_004639"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HDV1989710.1"
                     /translation="MTMKVGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAA
                     GAETASTAKAIAEQCDVIITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLA
                     SREISEALKAKGIDMLDAPVSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVV
                     HTGEIGAGNVTKLANQVIVALNIAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLD
                     AKAPMVMDRNFKPGFRIDLHIKDLANALDTSHGVGAQLPLTAAVMEMMQALRADGLGT
                     ADHSALACYYEKLAKVEVTR"
     gene            3214..4359
                     /gene="garK"
                     /locus_tag="RHX21_004640"
     CDS             3214..4359
                     /gene="garK"
                     /locus_tag="RHX21_004640"
                     /EC_number="2.7.1.165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312029.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate 2-kinase"
                     /protein_id="HDV1989711.1"
                     /translation="MKIVIAPDSYKESLSASEVAQAIEKGFREIFPDAQYVSIPVADG
                     GEGTVEAMIAATQGSERHAWVTGPLGEKVNASWGISGDGKTAFIEMAAASGLELVPAE
                     KRDPLVTTSRGTGELILQALESGATNIIIGIGGSATNDGGAGMVQALGAKLCDANGNE
                     IGFGGGSLNTLNDIDISGLDPRLKDCVIRVACDVTNPLVGDNGASRIFGPQKGASEAM
                     IVELDNNLSHYADVIKKALHVDVKDVPGAGAAGGMGAALMAFLGAELKSGIEIVTTAL
                     NLEEHIHDCTLVITGEGRIDSQSIHGKVPIGVANVAKKYHKPVIGIAGSLTDDVGVVH
                     QHGIDAVFSVLTSIGTLDEAFRGAYDNICRASRNIAATLAIGMRNAG"
     gene            4392..>4744
                     /gene="rnpB"
                     /locus_tag="RHX21_004641"
     ncRNA           4392..>4744
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="RHX21_004641"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
BASE COUNT         1109 a         1145 c         1369 g         1121 t
ORIGIN      
        1 acggcataaa tgaaactcat aaataacacc ttccccataa taataaaaat cagcataagt
       61 acccgaggta aataaaatga ttctggacac cgttgacgaa aaaaagaaag gcgtgcatac
      121 ccgctattta atattactga ttatttttat tgttaccgcc gttaactacg ccgatcgtgc
      181 aacgctgtct attgctggta ccgaagtggc aaaagagttg cagttaagtg cggtttcgat
      241 gggttacatc ttttctgctt ttggctgggc ctacttgctg atgcaaatcc ccggcggctg
      301 gctgcttgat aagtttggct cgaaaaaagt ttatacctat agcctctttt tctggtcgct
      361 attcactttc ctgcaaggct ttgttgatat gttcccgctg gcctgggcag ggatctccat
      421 gttctttatg cgctttatgc tcggcttctc ggaagcgcca tcattcccgg cgaacgcccg
      481 tattgtcgcc gcctggttcc cgacgaaaga acgtggtact gcctccgcca tctttaactc
      541 ggcgcaatat ttctcgctgg cgctcttttc gcctctgctt ggctggctga ctttcgcctg
      601 gggctgggag cacgtcttta ccgttatggg ggtgattggt tttgtgctga cggcgctgtg
      661 gatcaaattg attcataacc cgacagatca cccacgtatg tctgcggaag agctgaagtt
      721 tatctctgaa aatggcgcgg tggtcgatat ggaccacaaa aagccgggca gcgcggcagc
      781 aagcggtccc aaactgcatt acatcaagca attgctctct aaccgcatga tgttgggcgt
      841 atttttcgga caatatttta tcaacaccat cacctggttc ttcctcacct ggttcccgat
      901 ttatctggtg caggaaaaag gcatgtcgat tctgaaagtg ggtctggtcg cctcgattcc
      961 ggcactgtgt ggttttgcgg gcggcgtgct gggaggtgtc ttctcggatt atctgatcaa
     1021 acgcggttta tccctgaccc tggcacgtaa gctaccgatt gtgctgggaa tgttgctggc
     1081 ttccaccatc atcttatgta actacaccaa caacaccacg ctggtggtca tgctgatggc
     1141 gctggctttt tttggcaaag gatttggtgc tctgggctgg ccggtgattt ctgacaccgc
     1201 gccgaaagag attgttggcc tctgtggcgg cgtctttaac gtctttggca atgttgcctc
     1261 cattgtcact ccactggtga ttggctacct ggtaagtgaa ctgcactcct tcaatgcagc
     1321 actggttttc gtgggatgtt cagcgctgat ggcgatggtc tgctacctct tcgtagttgg
     1381 cgacattaaa cgtatggaat tgcagaaata agcaaaggta taagcgatga ataacgatgt
     1441 tttcccgaat aaattcaaag ccgcactggc tgcgaaacag gtacaaattg gttgctggtc
     1501 agcactctct aacccgatta gcactgaagt tcttggtttg gctgggtttg actggctggt
     1561 gctggatggc gaacatgcgc caaacgatat ctccacgttt attccgcagt taatggccct
     1621 gaaaggcagc gccagcgcgc cagtagtgcg agtgccgacc aacgagccgg taattattaa
     1681 gcgtcttctg gatatcggtt tctataactt cctgattcct tttgtagaaa caaaagagga
     1741 agcagagcag gcggtggcat caacccgtta cccaccggaa ggcattcgcg gcgtctccgt
     1801 ttctcaccgc gccaatatgt ttggcaccgt ggcggattat ttcgctcagt cgaacaagaa
     1861 catcaccatt ctggtccaga tagaaagtca gcagggcgta gataacgtcg atgccattgc
     1921 cgctaccgaa ggtgtagacg gtatcttcgt cggccccagc gatctggctg cggcattagg
     1981 ccatctcggc aatgcctcgc acccggatgt acaaaaagca attcagcaca tttttaaccg
     2041 tgccagtgcg cacggcaaac ccagcggtat tctcgcgccg gtcgaagccg atgcgcgtcg
     2101 ttatctggaa tggggcgcga cgtttgtggc tgtcggcagc gatcttggcg tcttccgctc
     2161 tgccactcag aaactggctg atacctttaa aaaataacca ccaccgcaac aagagagatg
     2221 attgatatga ctatgaaagt tggttttatt ggcctgggga ttatgggtaa accaatgagt
     2281 aaaaaccttc tgaaagcagg ttactcgctg gtggttgctg accgtaaccc agaagctatt
     2341 gctgacgtga ttgctgcagg tgcagaaaca gcgtctacgg ctaaagcgat cgctgaacag
     2401 tgcgacgtca tcataaccat gctgccaaac tcccctcatg tgaaagaggt ggcgctgggt
     2461 gagaatggca ttattgaagg cgcgaagcca ggtacggtat tgatcgatat gagttctatc
     2521 gcaccgctgg caagccgtga aatcagcgaa gcgctgaaag cgaaaggcat tgatatgctg
     2581 gatgctccgg tgagcggcgg tgaaccgaaa gccatcgacg gtacgctgtc agtgatggtg
     2641 ggcggcgaca aggctatttt cgacaaatac tatgatttga tgaaagcgat ggcgggttcc
     2701 gtggtgcata ccggggaaat cggtgcaggt aacgtcacca aactggcaaa tcaggtcatt
     2761 gtggcgctga atattgccgc gatgtcagaa gcgctaacgc tggcaaccaa agcgggcgtt
     2821 aacccggacc tggtgtatca ggcaattcgc ggtggactgg cgggcagtac cgtgctggat
     2881 gccaaagcgc cgatggtgat ggaccgcaac ttcaagccgg gcttccgtat tgatctgcat
     2941 attaaggatc tggcaaatgc gctggatact tcccacggcg tcggcgcgca actgccgctc
     3001 acagctgcgg ttatggagat gatgcaggca ctgcgagcag atggtttagg aacggcggat
     3061 catagcgccc tggcgtgcta ctacgaaaaa ctggcgaaag tcgaagttac tcgttaatga
     3121 cgtcgtgccc ggatggcgta ttgcaatccg ggcctggaat ccaggccgaa taagagaaac
     3181 gccctccggc gtcatgtggt aacaggcata ggtatgaaaa tcgtaatcgc cccagactct
     3241 tataaagaaa gtttatctgc cagcgaggtt gcgcaggcga tagaaaaagg atttcgggaa
     3301 atttttcctg atgcacagta cgtttctatt ccggttgccg acggtggcga aggaacggtg
     3361 gaagcgatga ttgcagccac ccagggttct gaacgtcacg cctgggttac agggccgctg
     3421 ggcgagaaag tgaatgccag ttgggggatc tccggcgatg gcaaaaccgc gtttattgaa
     3481 atggcggcgg ccagtgggct ggagctggta cctgcggaaa aacgcgatcc actcgtgacc
     3541 acttcacgcg gcacaggcga gttaatcctg caggcgctgg agagcggcgc gacaaacatt
     3601 attatcggca ttggcggtag cgctacaaat gatggcggcg caggcatggt acaggcgctg
     3661 ggggcgaaat tatgcgacgc caacggcaat gaaattggtt ttggcggcgg tagtcttaat
     3721 actctgaatg atattgatat ttccggcctc gatccgcgct taaaagattg cgtcattcgc
     3781 gtcgcttgtg atgtcaccaa tccgctggtg ggcgataacg gcgcatcgcg catctttggc
     3841 ccacaaaagg gagccagtga agcgatgatt gttgagctgg acaataacct ctctcactat
     3901 gccgatgtca ttaaaaaagc gctgcatgtt gatgtgaaag atgtccccgg cgcaggagct
     3961 gcgggcggta tgggtgcggc gctgatggcg tttcttggtg cggaactgaa aagtggtatt
     4021 gaaatcgtca ctacggcgct gaatctggag gaacatattc acgattgtac gctggtgatc
     4081 accggtgaag ggcgtattga cagccagagt attcacggca aggtaccgat tggcgttgca
     4141 aacgtggcga agaagtacca taaaccggtg attggcattg cgggtagcct gaccgatgat
     4201 gttggcgttg tacatcagca tggcatcgat gcggtcttca gcgtattgac cagcataggt
     4261 acgttggacg aagcattccg cggggcttat gacaatatct gccgtgcttc acgtaatatc
     4321 gccgcgacac tggcgattgg aatgcgcaac gcggggtgac aagggcgcgc aaaccctcta
     4381 tactgcgcgc cgaagctgac cagacagtcg ccgcttcgtc gtcgtcctct tcgggggaga
     4441 cgggcggagg ggaggaaagt ccgggctcca tagggcaggg tgccaggtaa cgcctggggg
     4501 ggaaacccac gaccagtgca acagagagca aaccgccgat ggcccgcgca agcgggatca
     4561 ggtaagggtg aaagggtgcg gtaagagcgc accgcgcggc tggtaacagt ccgtggcacg
     4621 gtaaactcca cccggagcaa ggccaaatag gggttcataa ggtacggccc gtactgaacc
     4681 cgggtaggct gcttgagcca gtgagcgatt gctggcctag atgaatgact gtccacgaca
     4741 gaac
//
LOCUS       DAPGUL010000219         4691 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.223, whole genome shotgun sequence.
ACCESSION   DAPGUL010000219 DAPGUL010000000
VERSION     DAPGUL010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4691
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.223"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            430..4683
                     /gene="fdeC"
                     /locus_tag="RHX21_004642"
     CDS             430..4683
                     /gene="fdeC"
                     /locus_tag="RHX21_004642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000092554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intimin-like adhesin FdeC"
                     /protein_id="HDV1989712.1"
                     /translation="MSRYKTGHKQPRFRYSVLARCVAWANISVQVLFPLAVTFTPVMA
                     ARAQHAVQPRLSMGNTTVTADNNVEKNVASFAANAGTFLSSQPDSDATRNFITGMATA
                     KANQEIQEWLGKYGTARVKLNVDKDFSLKDSSLEMLYPIYDTPTNMLFTQGAIHRTDD
                     RTQSNIGFGWRHFSGNDWMAGVNTFIDHDLSRSHTRIGVGAEYWRDYLKLSANGYIRA
                     SGWKKSPDIEDYQERPANGWDIRAEGYLPAWPQLGASLMYEQYYGDEVGLFGKDKRQK
                     DPHAISAEVTYTPVPLLTLSAGHKQGKSGENDTRFGLEVNYRIGEPLEKQLDTDSIRE
                     RRMLAGSRYDLVERNNNIVLEYRKSEVIRIALPERIEGKGGQTLSLGLVVSKATHGLK
                     NVQWEAPSLLAEGGKITGQGSQWQVTLPAYRPGKDNYYAISAVAYDNKGNASKRVQTE
                     VVITGAGMSADRTALTLDGQSRIQMLANGNEQRPLVLSLRDAEGQPVTGMKDQIKTEL
                     TFKPAGNIVTRTLKATKSQAKPTLGEFTETEAGVYQSVFTTGTQSGEATITVSVDGMS
                     KTVTAELRATMMDVANSTLSANEPSGDVVADGQQAYTLTLTAVDSEGNPVTGEASRLR
                     LVPQDTNGVTVGAISEIKPGVYSATVSSTRAGNVVVRAFSEQYQLGTLQQTLKFVAGP
                     LDAAHSSITLNPDKPVVGGTVTAIWTAKDAYDNPVTSLTPEAPSLAGAAAVGSTASGW
                     TNNGDGTWTAQITLGSTAGELEVMPKLNGQDAAANAAKVTVVADALSSNQSKVSVAED
                     HVKAGESTTVTLVAKDAHGNAISGLSLSASLTGTASEGATVSSWTEKGDGSYVATLTT
                     GGKTGELRVMPLFNGQPAATEAAQLTVIAGEMSSANSTLVADNKAPTVKTTTELTFTV
                     KDAYGNPVTGLKPDAPVFSGAASTGSERPSAGSWTEKGNGVYVSTLTLGSAAGQLSVM
                     PRVNGQNAVAQPLVLNVAGDASKAEIGDMTVKVNNQLANGQSANQITLTVVDSYGNPL
                     QGQEVTLTLPQGVTSKTGNTVTTNAAGKVDIELMSTVAGEHNISASVNGAQKTVTVKF
                     NADASTGQANLQVDTAVQKVANGKDAFTLTATVEDKNGNPVPGSLVTFNLPRGVKPLT
                     GDNVWVKANDEGKAELQVVSVTAGTYEITASAGNDQPSNAQSVTFVADKTTATISNIE
                     VIGNYALADGKAKQTYKVTVTDANNNLVKDSEVTLTASPASLNLEPNGTATTNEQGQA
                     IFTATTIVAATYTLKAQVSQTNGQVSTKTAESKFVADDKNAVLTASSDMQSLVADGKS
                     TAKLAVTLMSANNPVGGNMWVDIQTPEGVTEKDYQFLPSKNDHFVSGKIIRTFSTSKP
                     GVYTFTFNALTYGGYEMKPVTVTITAVDADTAKGEEAMK"
BASE COUNT         1247 a         1094 c         1297 g         1053 t
ORIGIN      
        1 aatctccgca atttacagtc cgatgaagga aaatgaatat ccataaaaaa tatatcgatt
       61 tattctggcg tatataccta cttcgacgta tttccaatag ttgttaatta aaggcaggcc
      121 attattattc actctgaata atgaattatt cactgtccgc agagtaaaaa atataactta
      181 ggtgtctatt taatgacttg cacaaaaagc taaattttca cccataaata aaaatataat
      241 cccgcgccca accacctgat gagtggctac agacactgga tatattaggt ggcggtgcac
      301 tttcttacat aaaggtattt ccttttctgc ggaaaaggaa atcgggaaat ccccggtttt
      361 tctgacaagc agacgccatt atttgtgtct gcctatgttc gttaattcgt tcatcaggaa
      421 attatctcaa tgtcgcgtta taaaacaggt cataaacaac cacgatttcg ttattcagtt
      481 ctggcccgct gcgtggcgtg ggcaaatatc tctgttcagg ttctttttcc actcgctgtc
      541 acctttaccc cagtaatggc ggcacgtgcg cagcatgcgg ttcagccacg gttgagcatg
      601 ggaaatacta cggtaactgc tgataataac gtggagaaaa atgtcgcgtc gtttgccgca
      661 aatgccggga catttttaag cagtcagcca gatagcgatg cgacacgtaa ctttattacc
      721 ggaatggcca cagctaaagc taaccaggaa atacaggagt ggctcgggaa atatggtact
      781 gcgcgcgtca aactgaatgt cgataaagat ttctcgctga aggattcttc gctggaaatg
      841 ctttatccga tttatgatac gccaacaaat atgttgttca ctcagggagc aatacatcgt
      901 accgacgatc gtactcagtc aaatattggt tttggctggc gtcatttttc aggaaatgac
      961 tggatggcgg gggtgaacac ctttatcgac catgatttat cccgtagtca tacccgcatt
     1021 ggtgttggtg cggaatactg gcgcgattat ctgaaactga gcgccaatgg ttatatccgg
     1081 gcttctggct ggaaaaaatc gccggatatt gaggattatc aggaacgccc ggcgaatggt
     1141 tgggatatcc gcgcagaggg ctatttacct gcctggccgc agcttggcgc aagcctgatg
     1201 tatgaacagt attatggcga tgaagtcggg ctgtttggta aagataagcg ccagaaagac
     1261 ccgcatgcta tttctgccga ggtgacctat acgccagtgc ctcttctgac actgagcgcc
     1321 gggcataagc agggcaagag cggtgagaat gacactcgct ttggcctgga agttaattat
     1381 cggattggcg aacctctgga gaaacaactc gatacagaca gcattcgcga gcgtcgaatg
     1441 ctggcaggca gccgctatga cctggttgag cgtaataaca acatcgttct tgagtaccgc
     1501 aaatctgaag tgatccgtat tgctctgcct gagcgtattg aaggtaaggg cggtcagaca
     1561 ctttccctgg ggcttgtggt cagcaaagca actcacggac tgaaaaatgt gcagtgggaa
     1621 gcgccgtcat tactggctga aggtggcaaa attaccggtc agggtagtca gtggcaagta
     1681 acgctcccgg cttatcgtcc aggtaaagac aattattatg cgatttctgc ggttgcctac
     1741 gataacaaag gcaatgcctc aaaacgcgtg cagacagagg tggtcattac cggagcaggt
     1801 atgagcgccg atcgcacggc gttaacgctt gacggtcaga gccgtattca aatgcttgct
     1861 aacggtaatg agcaaagacc gctggtgctg tctctgcgcg acgccgaggg ccagccagtc
     1921 acgggcatga aagatcagat caagactgaa ctaactttca aaccggctgg aaatattgtg
     1981 actcgtaccc tgaaggccac taaatcacag gcaaagccaa cactgggtga gttcaccgaa
     2041 actgaagccg gggtgtatca gtctgtcttt actaccggaa cgcagtcagg tgaggcaacg
     2101 attactgtta gcgttgatgg catgagcaaa accgtcactg cagaactgcg ggccacgatg
     2161 atggatgtgg caaactccac cctgagcgct aacgagccgt caggtgacgt ggttgctgat
     2221 ggtcagcaag cctacacgtt gacgttgact gcggtggact ccgagggtaa tccggtgacg
     2281 ggagaagcca gccgcctgcg acttgttccg caagacacta atggtgttac cgttggtgcc
     2341 atttcggaaa taaaaccagg ggtttacagc gccacggttt cttcgacccg tgccggaaac
     2401 gttgttgtac gtgccttcag cgagcagtat caactgggca cattacaaca aacgctgaag
     2461 tttgttgccg ggccgcttga tgcagcacat tcgtccatca ccctgaatcc tgataaaccg
     2521 gtggttgggg gtacagttac ggcaatctgg acggcaaaag atgcctatga caaccctgtg
     2581 accagcctca cgccggaagc gccgtcatta gcgggtgccg ctgctgtagg ttctacggca
     2641 tcgggctgga caaataatgg tgatgggacg tggactgcgc aaattactct cggctctacg
     2701 gcgggtgaat tagaagttat gccgaagcta aatggacagg atgcggcagc aaatgcggca
     2761 aaagtaaccg tggtggctga tgcgttatct tcaaaccagt cgaaagtctc tgtcgcagaa
     2821 gatcacgtaa aagccggcga aagcacaacc gtgacgctgg tggcgaaaga tgcgcatggc
     2881 aacgctatca gtggtctttc gttgtcggca agtttgacgg ggaccgcctc tgaaggggcg
     2941 accgtttcca gttggaccga aaaaggtgac ggttcctatg ttgctacgtt gactacaggc
     3001 ggaaagacgg gcgagcttcg tgtcatgccg ctcttcaacg gccagccagc agccaccgaa
     3061 gccgcgcagt tgacggtcat cgccggagag atgtcatcag cgaactctac gcttgttgcg
     3121 gacaataagg ctccgaccgt caaaacgacg acggaactca ccttcaccgt gaaggatgcg
     3181 tacgggaacc cggtcaccgg gctgaagcca gatgcaccag tgtttagcgg tgccgccagc
     3241 acggggagtg agcgtccttc agcaggaagc tggacagaga aaggtaatgg ggtctacgtg
     3301 tcgaccttaa cgctgggatc tgccgcgggt cagttgtctg tgatgccgcg agtgaacggc
     3361 caaaatgccg ttgctcagcc actggtgctg aacgttgcag gtgacgcatc taaggctgag
     3421 attggtgata tgacagtgaa ggttaataac caactggcta atggacagtc tgctaaccag
     3481 ataaccctga ccgtcgtgga cagctatggt aacccgttgc aggggcaaga agttacgctg
     3541 actttaccgc agggtgtgac cagcaagacg gggaatacag taacaaccaa tgcggcaggg
     3601 aaagtggaca ttgagcttat gtcaacggtt gcgggagaac acaatatttc cgcttcggtg
     3661 aatggtgctc agaagacggt cacggtgaaa tttaacgcgg atgccagcac cggtcaggca
     3721 aacctgcagg tagacaccgc cgttcaaaaa gtggcaaacg gcaaagacgc ctttacgctg
     3781 acggcgaccg ttgaggataa aaatggtaac cctgttccag ggagcctggt gacctttaat
     3841 ctgccccggg gtgtcaagcc gcttacaggc gataatgtct gggtgaaagc caacgatgag
     3901 gggaaagcag agttgcaggt ggtttcagtg actgccggaa cctatgagat cacggcgtcg
     3961 gcaggaaatg accagccttc gaatgcgcag tctgtaacgt ttgtggcgga taagactacg
     4021 gcaaccatct ccaatattga ggtgattggc aactatgcgc tggcggacgg caaagccaaa
     4081 caaacgtata aagttacggt gactgatgcc aataacaatt tggtgaaaga tagcgaagtg
     4141 acgctgactg ccagcccggc ttcgttaaac ctggaaccga atggcactgc gacaacgaat
     4201 gagcaagggc aggctatttt caccgctacc actattgttg cggcgacata cacactcaag
     4261 gcgcaagtga gtcagaccaa cggtcaggta tcaacgaaaa ctgccgaatc taaattcgtt
     4321 gcggatgata aaaacgcggt actcaccgca tcatctgata tgcaatctct agtggcggat
     4381 gggaaatcga ctgcgaagct ggcggtgacc ctgatgtcgg caaataaccc cgttggcggg
     4441 aatatgtggg tcgacattca gacgccggaa ggggtgacgg agaaggatta tcagttcctg
     4501 ccgtcgaaaa atgaccattt cgtgagcggg aaaatcatac gtacatttag taccagcaag
     4561 ccaggcgtct atacattcac atttaacgcc ctgacctatg gcgggtacga aatgaagcca
     4621 gtgacggtga ccattaccgc ggtggatgcc gatacggcaa agggcgagga ggcgatgaaa
     4681 taatttttaa g
//
LOCUS       DAPGUL010000220         4659 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.224, whole genome shotgun sequence.
ACCESSION   DAPGUL010000220 DAPGUL010000000
VERSION     DAPGUL010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4659
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.224"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..662
                     /gene="hprR"
                     /locus_tag="RHX21_004643"
     CDS             <1..662
                     /gene="hprR"
                     /locus_tag="RHX21_004643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707854.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="response regulator transcription factor HprR"
                     /protein_id="HDV1989713.1"
                     /translation="LIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDDYALI
                     ILDIMLPGMDGWQILQTLRTAKQTPVICLTARDSVDDRVRGLDSGANDYLVKPFSFSE
                     LLARVRAQLRQHHALNSTLEISGLRMDSVSQSVSRDNISITLTRKEFQLLWLLASRAG
                     EIIPRTVIASEIWGINFDSDTNTVDVAIRRLRAKVDDPFPEKLIATIRGMGYSFVAVK
                     K"
     gene            662..2020
                     /gene="hprS"
                     /locus_tag="RHX21_004644"
     CDS             662..2020
                     /gene="hprS"
                     /locus_tag="RHX21_004644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HprS"
                     /protein_id="HDV1989714.1"
                     /translation="MKRLSITVRLTLLFILLLSVAGAGIVWTLYNGLASELKWRDDTT
                     LINRTAQIKQLLIDGVNPDTLPVYFNRMMDVSQDILIIHGDSINKIVNRTNVSDDMLN
                     NIPASETISAAGIYRSIINDTEIDALRINIDEVSPSLTVTVAKLASARHNMLEQYKIN
                     SIIICIVAIVLCSVLSPLLIRTGLREIKKLSGVTEALNYNDSREPVEVSALPRELKPL
                     GQALNKMHHALVKDFERLSQFADDLAHELRTPINALLGQNQVTLSQTRSIAEYQKTIA
                     GNIEELENISRLTENILFLARADKNNVLVKLDSLSLNKEVENLLDYLEYLSDEKEICF
                     KVECNQQIFADKILLQRMLSNLIVNAIRYSPEKSRIHITSFLDTNGYLNIDIASPGTK
                     INEPEKLFRRFWRGDNSRHSEGQGLGLSLVKAIAELHGGSATYHYFNKHNVFRITLPQ
                     RN"
     gene            complement(2128..2979)
                     /gene="hchA"
                     /locus_tag="RHX21_004645"
     CDS             complement(2128..2979)
                     /gene="hchA"
                     /locus_tag="RHX21_004645"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein deglycase HchA"
                     /protein_id="HDV1989715.1"
                     /translation="MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKP
                     YRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMT
                     KFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIG
                     LPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTP
                     EIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKVLTGDSPFAANALGKLAAQE
                     MLAAYAG"
     gene            3235..3432
                     /locus_tag="RHX21_004646"
     CDS             3235..3432
                     /locus_tag="RHX21_004646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989716.1"
                     /translation="MMWNIVVLMNIYIPDWWRKSFFHALFLQKFLYGRRVCCGLIHKE
                     MYLECWLDESLVDVIVPAGAG"
     gene            complement(3572..4645)
                     /locus_tag="RHX21_004647"
     CDS             complement(3572..4645)
                     /locus_tag="RHX21_004647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_063070036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
                     /protein_id="HDV1989717.1"
                     /translation="MKRKVLAMLVPALLVAGAANAAEIYNKDGNKVDFYGKMVGERIW
                     SNTDDNNSENEDTSYARFGVKGETQITSELTGFGQFEYNLDASKPEGSNQEKTRLTFA
                     GLKYNELGSFDYGRNYGVAYDAAAYTDMLVEWGGDSWASADNFMNGRTNGVATYRNSD
                     FFGLVDGLNFAVQYQGKNSNRGVTKQNGDGYALSVDYNIEGFGFVGAYSKSDRTNEQA
                     SDGYGDNAEVWSLAAKYDANNIYAAMMYGETRNMTVLANDHFANKTQNFEAVVQYQFD
                     FGLRPSLGYVYSKGKDLYARDGHKGVDADRVNYIEVGTWYYFNKNMNVYTAYKFNLLD
                     KDDAAITDAATDDQFAVGIVYQF"
BASE COUNT         1308 a          939 c         1079 g         1333 t
ORIGIN      
        1 tacttattga agataatcaa aggacccagg agtgggtaac gcaggggctt tccgaagcgg
       61 gttatgtcat tgatgccgtt tctgatggca gagatgggct ttatcttgcg ctgaaggatg
      121 attatgcatt gatcattctg gatattatgc ttccgggtat ggatggctgg cagatcttac
      181 aaacgttaag aacagcaaag caaacccctg ttatttgcct tactgcaagg gattctgtcg
      241 atgacagagt cagagggctg gacagtggag caaatgatta tctggtaaaa cctttttcat
      301 tttctgagtt gctggcaagg gttcgggcac aattaaggca acatcacgct ttgaattcaa
      361 cattagaaat cagtggctta agaatggact ctgtaagtca aagtgtgagc agggacaata
      421 tcagtattac actgacgcgc aaggagtttc agttactttg gctactggcc tccagagctg
      481 gcgaaattat acccagaacg gttattgcga gtgaaatttg gggaatcaac tttgatagtg
      541 ataccaatac ggtggatgtc gccattcgca ggctccgcgc aaaagttgat gatccttttc
      601 ctgaaaagct aatcgccaca atccggggga tgggctattc attcgtagcg gtaaaaaaat
      661 aatgaaaaga ttatctataa ccgtccgttt aaccttgctt tttatattgc tgctgtctgt
      721 tgctggcgct ggaattgtct ggactctcta taatggcctg gcaagtgagt tgaaatggcg
      781 cgatgataca acactcatta accggacagc acagatcaag cagttgttaa ttgatggggt
      841 aaatccagat acgttacctg tatactttaa ccggatgatg gatgttagtc aggatatctt
      901 gatcattcat ggtgatagca tcaataaaat tgttaaccgg acaaatgtca gtgatgacat
      961 gttaaataac atacctgcta gtgagacaat cagcgcagct ggcatttaca gaagcattat
     1021 taatgatact gagattgatg ctttacgaat taatattgat gaagtttcgc catcattaac
     1081 ggttactgtg gctaaattgg cttcagccag acataacatg cttgaacagt ataaaattaa
     1141 tagcattata atttgcattg tcgccattgt actttgctca gtattaagtc cgctgttaat
     1201 cagaacggga ttacgagaga tcaaaaagtt gagtggtgta acggaagcgc tgaattataa
     1261 cgatagccgg gagcctgttg aggttagcgc attaccgaga gaactaaaac ctcttgggca
     1321 ggcgttgaat aaaatgcatc atgctttagt caaagatttt gagcgtctaa gtcaatttgc
     1381 tgacgatctc gctcatgaac ttagaacgcc cattaatgca ttactgggtc agaatcaggt
     1441 tacgctcagt caaaccagaa gtatcgctga atatcaaaaa acaattgccg gtaacattga
     1501 agagctggaa aatatttcgc ggttaacaga gaacatactg tttcttgccc gggcagataa
     1561 aaacaatgtt ttggtgaaac tggactcgct ttctctcaat aaggaagtcg aaaatttgtt
     1621 ggattatctt gaataccttt cagacgagaa agagatttgc tttaaggtcg agtgcaatca
     1681 gcaaatcttt gcggataaaa ttttactgca acgaatgtta tcgaatctta ttgttaatgc
     1741 cattagatat tcaccagaaa aatcgcgcat tcatataacc agttttcttg ataccaacgg
     1801 ctatcttaat attgatatcg ccagtcctgg aacgaaaatt aatgagcctg aaaaactctt
     1861 ccgtagattt tggcggggag ataattcgcg tcattccgaa ggtcagggac ttggtctttc
     1921 tttagtcaaa gcgattgccg aattgcatgg gggaagtgct acgtatcact attttaataa
     1981 gcataatgtg ttccgaatta cgttaccgca aagaaattaa catagggctt cagtacgcca
     2041 taaatcaacc atgaaaaaac gcagccacgt cgtgagtatt aacgtggctg cgattgatta
     2101 tgcgcttaca ttcatacgta acagggatta acccgcataa gctgccagca tttcctgcgc
     2161 cgccagttta cccaacgcat tcgctgcgaa aggactgtcg ccggtgagaa ctttacggtc
     2221 cttatgtact cgcccagtga tgtcgtcatt aataatgttc atgcccattt tcttcagctc
     2281 ttcgccgaag taccaggtga gatgacccgg catatagcct atctctggcg tttgtttgtc
     2341 tgcggcgtct gggaatgcgc aaatggaata accattcagt gggttatcgc cgtggcgaag
     2401 cgccagaaaa gccgccgggc cgtggcaaag ggagataacg aaacggtcat ttttgattgc
     2461 ccactgtaaa gcggcagcta cgtcctggct ttcaggtaaa ccaataagtg cgccatgacc
     2521 accaggaaca aagattgctg catattcgct atcagcgttg aggctggcga caacatccgc
     2581 gagtttcttc ggattgcgga acaacgattt atgctgctca aagaatggca ttactttttc
     2641 atctttgtgc ggcatagccc agtattcaaa cttggtcatc agaccggaaa tggtcgccac
     2701 ttcgaattcg aaacctgcag catggagatg atacaacggc agcaacgttt caatcggatg
     2761 gttaccggtc gagaacagtt tcccgttatc ggtcggcaaa taacgttcgt ccgcggcgat
     2821 caccagaatt ttatgtttac cgcgatacgg ttttggatag tccacgccat caagatcaga
     2881 gacaggactg gtatattggc taagcgaata ttctgaaggg aagaatgcat tatcttcagc
     2941 aatatcgacc tgcggatttt tacttgtttg aacagtcata gtgtattcct tattgttgct
     3001 tagttagggt agtcactata tttgcgactg agctggtcgc tatttttaac caggctggaa
     3061 aattgagtca atatatcgaa agcggtagtc ggcgggtgta agtatgtaat gatgatgctg
     3121 cactggtgtt gaatattatt cacgccaaat tttccttatt gagcaacgtc gtcgcaagtg
     3181 gcctcaatga ttttagacca ttatcagagg tacggggcgg cggggagaga tttagtgatg
     3241 tggaatattg tggtgctgat gaatatttat atcccggatt ggtggagaaa aagctttttc
     3301 catgcacttt ttttgcaaaa atttctatat gggaggcgtg tttgttgcgg gttaattcat
     3361 aaagaaatgt atttggagtg ttggctggat gagtcgctgg tagatgttat tgtgccagca
     3421 ggggcagggt aaggtactgt atcgatatgc tttggcaatt gcgtgtgccg gagatggaga
     3481 tgaaatgcca ataaaaaagc ctgagttcga tgagggacga actcaggcta gtgttaagtt
     3541 ttacagtaac acgccgcggc gagttggctg attagaactg gtagacgata ccaactgcaa
     3601 actggtcatc agttgcggca tcggtaatcg ctgcatcgtc tttatccagc aggttaaact
     3661 tgtatgctgt gtagacgttc atgttcttat tgaagtagta ccaggtacca acttcgatat
     3721 aatttacgcg gtcagcatca acacctttat gtccatcacg agcataaaga tctttgcctt
     3781 tggaatatac gtagcctaaa gacggacgta aaccgaagtc gaactgatac tgtacaacag
     3841 cttcaaagtt ttgggtttta tttgcaaaat gatcattagc caaaacggtc atgttgcggg
     3901 tttcaccgta catcattgct gcatagatat tatttgcatc atacttggct gctaatgacc
     3961 acacttcagc gttatcaccg tagccgtcac tagcttgttc attagtacga tcagatttgc
     4021 tatatgcacc tacaaaacca aaaccttcga tgttgtagtc tacagacaac gcatagccat
     4081 caccgttttg tttagtaacg ccacgattgc tgttcttacc ttgatattgc acagcaaaat
     4141 tcagaccatc aaccagacca aagaaatcag agttacggta ggttgcaaca ccgttggtac
     4201 gaccgttcat gaagttgtca gcggaagccc aggaatcacc accccattca actaacatat
     4261 cggtataagc tgcggcatca taagcaacac cgtagttacg accatagtcg aaagatccta
     4321 actcgttata tttcaaacct gcgaaggtta aacgagtttt ttcctgatta gagccttcgg
     4381 gcttgctggc gtcgaggttg tattcaaact gaccaaaacc agtcagttcg ctggtgattt
     4441 gtgtttcacc tttaacaccg aaacgagcat aggaggtatc ttcgttttcg ctgttattat
     4501 catcagtatt tgaccagatg cgttcgccaa ccatcttgcc gtagaaatca actttattgc
     4561 catctttatt ataaatttca gccgcatttg ctgcgccagc aactaataac gccgggacca
     4621 gcattgccag aacttttctt ttcattatgt attcccttg
//
LOCUS       DAPGUL010000221         4518 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.225, whole genome shotgun sequence.
ACCESSION   DAPGUL010000221 DAPGUL010000000
VERSION     DAPGUL010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4518
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.225"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..337)
                     /gene="tuf"
                     /locus_tag="RHX21_004648"
     CDS             complement(<1..337)
                     /gene="tuf"
                     /locus_tag="RHX21_004648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDV1989718.1"
                     /translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAA
                     RAFDQIDNAPEEKARGITINTSHVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVAATDGP"
     gene            complement(452..527)
                     /locus_tag="RHX21_004649"
     tRNA            complement(452..527)
                     /locus_tag="RHX21_004649"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(492..494),aa:Thr,seq:ggt)
     gene            complement(534..608)
                     /locus_tag="RHX21_004650"
     tRNA            complement(534..608)
                     /locus_tag="RHX21_004650"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(573..575),aa:Gly,seq:tcc)
     gene            complement(725..809)
                     /locus_tag="RHX21_004651"
     tRNA            complement(725..809)
                     /locus_tag="RHX21_004651"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(773..775),aa:Tyr,seq:gta)
     gene            complement(818..893)
                     /locus_tag="RHX21_004652"
     tRNA            complement(818..893)
                     /locus_tag="RHX21_004652"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(858..860),aa:Thr,seq:tgt)
     gene            1255..2205
                     /gene="coaA"
                     /locus_tag="RHX21_004653"
                     /gene_synonym="panK"
     CDS             1255..2205
                     /gene="coaA"
                     /locus_tag="RHX21_004653"
                     /gene_synonym="panK"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HDV1989719.1"
                     /translation="MSIKEQTLMTPYLQFDRNQWAALRDSVPMTLSEDEIARLKGINE
                     DLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKS
                     TTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFV
                     SDLKSGVPNVTAPVYSHLIYDVIPDGDKTVVQPDILILEGLNVLQSGMDYPHDPHHVF
                     VSDFVDFSIYVDAPEDLLQTWYINRFLKFREGAFTDPDSYFHNYAKLTKEEAIKTAMT
                     LWKEINWLNLKQNILPTRERASLILTKSANHAVEEVRLRK"
     gene            complement(2234..3199)
                     /gene="birA"
                     /locus_tag="RHX21_004654"
     CDS             complement(2234..3199)
                     /gene="birA"
                     /locus_tag="RHX21_004654"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HDV1989720.1"
                     /translation="MKDNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLR
                     DWGVDVFTVPGKGYSLPEPIQLLNAEQILGQLDGGSVAVLPVIDSTNQYLLDRIGELK
                     SGDACVAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEV
                     LRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESV
                     VNQGWITLQEAGINLDRNTLAAMLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPV
                     KLIIGDKEIFGISRGIDKQGALLLEQDGIIKPWMGGEISLRSAEK"
     gene            complement(3196..4224)
                     /gene="murB"
                     /locus_tag="RHX21_004655"
     CDS             complement(3196..4224)
                     /gene="murB"
                     /locus_tag="RHX21_004655"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HDV1989721.1"
                     /translation="MNHSLKPWNTFGIDHNAQHIVCAEDEQQLLNAWQYATAEGQPVL
                     ILGEGSNVLFLEDYRGTVIINRIKGIEIHDEPDAWYLHVGAGENWHRLVKYTLQEGMP
                     GLENLALIPGCVGSSPIQNIGAYGVELQRVCAYVDCVELATGKQVRLTAKECRFGYRD
                     SIFKHEYQDRFAIVAVGLRLPKEWQPVLTYGDLTRLDPTTVTPQQVFNAVCHMRTTKL
                     PDPKVNGNAGSFFKNPVVSAETAKALLAQFPTAPNYPQAGGSVKLAAGWLIDQCQLKG
                     MQMGGAAVHRQQALVLINEDNAKSEDVVQLAHHVRQKVGEKFNVWLEPEVRFIGASGE
                     VSAVETIS"
BASE COUNT         1145 a         1139 c         1026 g         1208 t
ORIGIN      
        1 tcgggccgtc agtcgcagca actaccagga tcgcgccgtc catctgagca gcaccggtga
       61 tcatgttttt aacatagtcg gcgtgccccg ggcagtctac gtgtgcgtag tgacgggtcg
      121 gggtgtcgta ttcaacgtga gaagtgttga tggtgatacc acgagctttt tcttccggcg
      181 cgttatcgat ctggtcgaat gcgcgagcag caccgccgta ggttttagcc agtacggtag
      241 tgattgcagc ggtcagcgtt gttttaccat ggtcaacgtg gccgatagta ccgacgttaa
      301 cgtgcggttt tgtacgttca aacttttctt tagacatcga ttgtccctct aagacacgga
      361 taaatcggtg atatcaccac atcaaccagg caacatgccc gacttgttga atgcaataaa
      421 cagaaggaaa aaacagggag gagaaaagaa gtggtgctga taggcagatt cgaactgccg
      481 acctcaccct taccaagggt gcgctctacc aactgagcta tatcagcaca tcttggagcg
      541 ggcagcggga atcgaacccg catcatcagc ttggaaggct gaggtaatag ccattatacg
      601 atgcccgcat cctggaactc ggctacctga ttttcattct gcactgaata tcgagagaag
      661 ctctctttat tcgagccggt aagcgaactt atcgtctcgg gctacgccat cgcgtggccg
      721 aaattggtgg tgggggaagg attcgaacct tcgaagtctg tgacggcaga tttacagtct
      781 gctccctttg gccgctcggg aaccccaccg gacttgatgg tgccgactac cggaatcgaa
      841 ctggtgacct actgattaca agtcagttgc tctacctact gagctaagtc ggcatcaagt
      901 agcgcgcatt ctatggagac atgcgagttc atgcaactaa aaaattgcat aatttgtttt
      961 attggtcaca ttttatgcga cacgatgaag aaacagccga acggagggca gattagcaca
     1021 ctttttcaac atcattgtgc tcaacaatgc gctcctgcta aaccataatt ctttttatca
     1081 gatggaatat ctgtcacatt gcttttcaac gatagcttcc tggcagagat tttttcttat
     1141 tattcctccc catctggtgt taccctcctg cccattaacc cattcaacag aactgtgacg
     1201 cgccatggca aatatcgctt tgccgataga gctatgaccg ccagaaacat gcttatgagt
     1261 ataaaagagc aaacgttaat gacgccttac ctacagtttg accgcaacca gtgggcagct
     1321 ctgcgtgatt ccgtacctat gacgttatcg gaagatgaga tcgcccgtct caaaggtatt
     1381 aatgaagatc tctcgttaga agaagttgcc gagatctatt tacctttgtc acgtttgctg
     1441 aacttctata taagctcgaa tctgcgccgt caggcagttc tggaacagtt tcttggtacc
     1501 aacgggcaac gcattcctta cattatcagt attgctggca gtgtcgcggt ggggaaaagt
     1561 acaaccgccc gtgtattgca ggcgctatta agccgttggc cggaacatcg tcgtgttgaa
     1621 ctgatcacta cagatggctt ccttcaccct aatcaggttc tgaaagaacg tggtctgatg
     1681 aagaagaaag gcttcccgga atcgtatgat atgcatcgcc tggtgaagtt tgtttccgat
     1741 ctcaaatccg gcgtgccaaa cgttacagcc cctgtttact cgcatcttat ttatgatgtg
     1801 atcccggatg gagataaaac ggttgttcag cctgatattt taattcttga agggttaaat
     1861 gtcttacaga gcgggatgga ttatccacac gatccacatc atgtatttgt ttctgatttt
     1921 gtcgattttt cgatatatgt tgatgcaccg gaagacttac ttcagacgtg gtatatcaac
     1981 cgttttctga aattccgcga aggggctttt accgacccgg attcctattt tcataactac
     2041 gcgaaattaa ctaaagaaga agcgattaag actgccatga cattgtggaa agagatcaac
     2101 tggctgaact taaagcaaaa tattctacct actcgtgagc gcgccagttt aatcctgacg
     2161 aaaagtgcta atcatgcggt agaagaggtc agactacgca aataatttgc aggggagcga
     2221 atactcccct ttcttatttt tctgcactac gcagggatat ttcaccgccc atccagggtt
     2281 ttattattcc atcctgctca agtaataaag ccccctgttt gtctattccg cgtgaaatgc
     2341 caaatatttc tttatcacca atgataagtt tcactgggcg attaataaaa ttatccagct
     2401 tttcccagcg cgacagataa ggtgccaatc cttcttgttc gaagagttcc aacgcagcac
     2461 gtaattcacg tattagcatg gccgccaacg tattacgatc gagattgatc cccgcttcct
     2521 gcagcgtgat ccacccctga ttaacgacac tctcttcaac acggcgcatt gccatgttga
     2581 tcccggctcc aatgactatt tgcgccgcat cgccagtttt gccagtcagc tccacaagaa
     2641 tgcctgccag cttgcgatcc tgcagataga ggtcattagg ccatttgaca cgaactttat
     2701 ctgctcccag cttgcgtaat acttccgcca tcacgatacc gataaccaga cttaaaccaa
     2761 tcgccgccgc cgggccttgt tccagacgcc agaacatcga caaatataag tttgcgccaa
     2821 aaggcgaaaa ccatttccgc ccccggcgac cacggccagc ctgctggtat tctgcaacac
     2881 aggcatcgcc cgatttaagc tctccgatac gatcaagaag gtactgattc gtggagtcaa
     2941 taactggcag cacggctaca ctaccgccat ccagctgacc caatatctgt tcagcattaa
     3001 gtaactggat gggctcaggc aggctgtatc ctttacccgg aacggtaaag acatcaacgc
     3061 cccagtcacg cagtgtctga atgtgtttat taatagccgc ccggctcatt cccagcgttt
     3121 cacccaactg ctcgccagag tgaaattcac cgttcgctaa cagggcaatc aatttcagtg
     3181 gcacggtgtt atccttcatg aaattgtctc cactgcgctc acttcacctg atgcaccaat
     3241 aaagcggact tcaggctcaa gccagacatt aaatttttca cccacttttt gtcttacatg
     3301 gtgtgccagt tgcaccacat cttcgctttt tgcattgtct tcattaatga gaactaacgc
     3361 ctgttgacgg tgcaccgcag ccccacccat ttgcatccct tttagctggc actgatcaat
     3421 aagccaacct gctgccagtt ttactgaacc acccgcctgg gggtaatttg gtgctgttgg
     3481 aaattgcgcc agtaatgctt tagccgtttc ggcagataca acagggtttt tgaagaaact
     3541 accggcattg ccattcactt ttggatcagg gagtttggtg gtgcgcatat gacacaccgc
     3601 attaaatact tgctgtggcg ttactgttgt aggatccaga cgagttaagt caccatacgt
     3661 tagtacaggt tgccactctt ttggcagacg cagacctacg gctacaatgg cgaagcgatc
     3721 ctggtattca tgtttaaaaa tactgtcgcg atagccaaaa cggcactctt tggcagttaa
     3781 gcgcacttgc ttgcctgtcg ccagttcaac acaatcaaca taagcgcaaa ctcgctgtaa
     3841 ttctacgcca taagcaccaa tattctggat aggtgatgag ccgacacaac caggaattaa
     3901 tgccagattt tccagaccag gcataccttc ctgcaaagtg tattttacca ggcgatgcca
     3961 gttttctccg gctcctacat gtaaatacca cgcatcaggt tcatcatgaa tttcgatacc
     4021 tttgatccgg ttgatgatca ccgtgccgcg atagtcttcc agaaaaagta cattacttcc
     4081 ttcacccaga ataagaacgg gttgtccttc tgcggttgca tactgccagg cattgagtaa
     4141 ttgttgttcg tcttcggcac atacaatgtg ctgagcatta tgatcaatgc caaatgtgtt
     4201 ccagggtttt aaggagtggt tcatagctgc tttcctgatg caaaaacgag gctagtttac
     4261 cgtatctgtg gggggatggc ttgtagatat gacgacagga agagtttgta gaaacgcaaa
     4321 aaggccatcc gtcaggatgg ccttctgctt aatttgatgc ctggcagttt atggcgggcg
     4381 tcctgcccgc caccctccgg gccgttgctt cgcaacgttc aaatccgctc ccggcggatt
     4441 tgtcctactc aggagagcgt tcaccgacaa acaacagata aaacaaaagg cccagtcttt
     4501 cgactgagcc ttttgttt
//
LOCUS       DAPGUL010000222         4416 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.226, whole genome shotgun sequence.
ACCESSION   DAPGUL010000222 DAPGUL010000000
VERSION     DAPGUL010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4416)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4416)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4416
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.226"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            105..533
                     /gene="uspC"
                     /locus_tag="RHX21_004656"
     CDS             105..533
                     /gene="uspC"
                     /locus_tag="RHX21_004656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspC"
                     /protein_id="HDV1989722.1"
                     /translation="MSYSNILVAVAVTPESQQLLAKAVSIARPVKGHISLITLASDPE
                     MYNQLAAPMLEDLRSVMQEETQSFLDKLIQDAGYPVDKTFIAYGELSEHILEVCHKHH
                     FDLVICGNHNHSFFSRASCSAKRVIASSEVDVLLVPLTGD"
     gene            complement(540..1964)
                     /gene="otsA"
                     /locus_tag="RHX21_004657"
     CDS             complement(540..1964)
                     /gene="otsA"
                     /locus_tag="RHX21_004657"
                     /EC_number="2.4.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalose-phosphate synthase"
                     /protein_id="HDV1989723.1"
                     /translation="MSRLVVVSNRIAPPDEHAASAGGLAVGILGALKAAGGLWFGWSG
                     ETGNEDQPLKKVKKGNITWASFNLSEQDLDEYYNQFSNAVLWPAFHYRLDLVQFQRPA
                     WDGYLRVNALLADKLLPLLQDDDIIWIHDYHLLPFAHELRKRGVNNRIGFFLHIPFPT
                     PEIFNALPTYDTLLEQLCDYDLLGFQTENDRLAFLDCLSNLTRVTTRSAKSHTAWGKA
                     FRTEVYPIGIEPKEIAKQAAGPLPPKLAQLKAELKNVQNIFSVERLDYSKGLPERFLA
                     YEALLEKYPQHHGKIRYTQIAPTSRGDVQAYQDIRHQLENEAGRINGKYGQLGWTPLY
                     YLNQHFDRKLLMKIFRYSDVGLVTPLRDGMNLVAKEYVAAQDPANPGVLVLSQFAGAA
                     NELTSALIVNPYDRDEVAAALDRALTMSLAERISRHAEMLDVIVKNDINHWQECFISD
                     LKQIVPRSAESQQRDKVATFPKLA"
     gene            complement(1939..2739)
                     /gene="otsB"
                     /locus_tag="RHX21_004658"
     CDS             complement(1939..2739)
                     /gene="otsB"
                     /locus_tag="RHX21_004658"
                     /EC_number="3.1.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose-phosphatase"
                     /protein_id="HDV1989724.1"
                     /translation="MTEPLTETPELSAKYAWFFDLDGTLAEIKPHPDQVVVPDNILQG
                     LQLLATASDGALALISGRSMVELDALAKPYRFPLAGVHGAERRDINGKTHIVHLPDAI
                     ARDISVQLHTVIAQYPGAELEAKGMAFALHYRQAPQHEDALMTLAQRITQIWPQMALQ
                     QGKCVVEIKPRGTSKGEAIAAFMQEAPFIGRTPVFLGDDLTDESGFAVVNRLGGMSVK
                     IGTGATQASWRLAGVPDVWSWLEMITTALQQKRENNRSDDYESFSRSI"
     gene            complement(2906..3892)
                     /gene="araH"
                     /locus_tag="RHX21_004659"
     CDS             complement(2906..3892)
                     /gene="araH"
                     /locus_tag="RHX21_004659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter permease AraH"
                     /protein_id="HDV1989725.1"
                     /translation="MSSVSTSGSGAPKSSFSFGRIWDQYGMLVVFAVLFIACAIFVPN
                     FATFINMKGLGLAISMSGMVACGMLFCLASGDFDLSVASVIACAGVTTAVVINLTESL
                     WIGVAAGLLLGVLCGLVNGFVIAKLKINALITTLATMQIVRGLAYIISDGKAVGIEDE
                     SFFALGYANWFGLPAPIWLTVACLIIFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVV
                     RTKIIIFVLSGLVSAIAGIILASRMTSGQPMTSIGYELIVISACVLGGVSLKGGIGKI
                     SYVVAGILILGTVENAMNLLNISPFAQYVVRGLILLAAVIFDRYKQKAKRTV"
     gene            complement(3907..>4416)
                     /gene="araG"
                     /locus_tag="RHX21_004660"
     CDS             complement(3907..>4416)
                     /gene="araG"
                     /locus_tag="RHX21_004660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter ATP binding protein
                     AraG"
                     /protein_id="HDV1989726.1"
                     /translation="CPEDRKAEGIIPVHSVRDNINISARRKHVLGGCVINNGWEENNA
                     DHHIRSLNIKTPGAEQLIMNLSGGNQQKAILGRWLSEEMKVILLDEPTRGIDVGAKHE
                     IYNVIYALAAQGVAVLFASSDLPEVLGVADRIVVMREGEIAGELLHEQADERQALSLA
                     MPKVSQAVA"
BASE COUNT         1129 a         1152 c         1047 g         1088 t
ORIGIN      
        1 atcagactaa tatttaccag tttgaccgag ttgggattgc gtcgtttctc cattaggagt
       61 aaagctttaa tgtcacctga agttcacaga ataaggaaca ggttatgagc tatagcaata
      121 ttcttgtcgc tgttgcggtt acaccggaaa gtcagcaact gctggcaaaa gcggtatcta
      181 tcgccaggcc agtaaaggga cacatcagtt taattactct cgcttccgac ccggaaatgt
      241 acaatcaatt agctgcgccg atgcttgaag atttacgcag cgtgatgcag gaagaaacgc
      301 aaagctttct tgataagtta attcaggatg cggggtatcc cgttgacaag acgtttattg
      361 cctacggtga gttaagcgaa catattctgg aagtatgtca caagcatcat ttcgatttgg
      421 tgatttgcgg taatcacaat cacagtttct tttcgcgagc atcctgctcg gcgaaaagag
      481 ttattgcctc aagtgaggtc gatgtgctgt tagttccact tacgggagat taaccgctcc
      541 tacgcaagct ttggaaaggt agcaacttta tcgcgctgct ggctttccgc gcttcgcgga
      601 actatctgct ttaggtcgct aatgaagcac tcctgccagt ggttaatatc gtttttcacg
      661 ataacgtcca gcatttctgc atgacgggaa atacgttccg ccagcgacat agtcaatgca
      721 cgatccagcg cagctgcaac ttcgtcacga tcgtaggggt taacaattaa cgccgacgtt
      781 aactcgtttg ccgctcccgc aaattgcgaa agaacaagaa cgcccggatt ggctgggtcc
      841 tgagcagcaa catactcttt tgctaccagg ttcatcccgt cacgcagtgg cgtcactaag
      901 cccacgtcag agtagcggaa tattttcatc agtaatttac ggtcaaaatg ctgattcaaa
      961 taataaagcg gcgtccagcc taattgcccg tatttaccat taattcgtcc agcttcattt
     1021 tcgagctgat gacgaatatc ctgataggct tgcacatcac cacgcgacgt tggtgcaatc
     1081 tgggtataac gaattttacc atgatgctgc ggatattttt ccagcaacgc ttcataggcg
     1141 agaaaacgct ctggcaaacc tttggaataa tccagccgtt cgacagaaaa gatattttgt
     1201 acgtttttca gttccgcttt aagttgcgcc agttttggcg gcagtggccc ggcagcctgt
     1261 ttggctattt ctttcggttc aatgccgatc gggtagactt ctgttcgaaa tgctttgccc
     1321 caggctgtat ggctttttgc gctacgtgtc gtgacgcggg tcaggttaga aagacaatcc
     1381 aggaacgcca gacgatcgtt ttctgtctgg aaacccagca aatcataatc acaaagctgt
     1441 tcaagcaagg tgtcatatgt cggcagcgcg ttgaagattt ccggtgtcgg gaaaggaata
     1501 tgcagaaaga aaccaatgcg attattcact ccccgtttgc gtaattcatg cgcaaatggc
     1561 aacaggtgat aatcgtggat ccagataatg tcatcgtctt gcaacagcgg cagtaattta
     1621 tctgccagca acgcatttac gcgtagatag ccgtcccagg caggacgctg aaattgcacc
     1681 agatcgagcc gataatgaaa agcgggccag agaacggcat tggagaattg gttgtagtat
     1741 tcgtcaaggt cctgttcgct gaggttaaaa gaggcccacg taatgttacc ttttttcacc
     1801 ttttttagcg gctgatcctc attccctgtt tcaccactcc agccaaacca cagtccgcct
     1861 gcggctttca gtgcccccag tatgccaacg gcaaggccac cggcactggc ggcgtgctcg
     1921 tctggtggtg caatccggtt agatactacg actaaacgac tcatagtcat cactcctgtt
     1981 attttctctt ttttgttgta atgcggtggt tatcatttca agccagctcc agacatccgg
     2041 cacacccgcc agtcgccatg atgcctgagt tgcacctgtg ccaattttta ctgacattcc
     2101 gcccagtcgg ttaacgactg cgaagccaga ttcatcggtt aaatcatcgc ccagaaatac
     2161 gggcgttcgc ccgataaagg gagcttcctg cataaaagct gcaattgcct cacctttact
     2221 ggtacctctc ggtttgatct cgacaacaca ctttccctgc tgtaacgcca tttgtggcca
     2281 gatctgagta atacgttgcg ctaatgtcat taatgcgtct tcatgctgcg gagcctgacg
     2341 ataatgcagc gcaaaagcca tccctttcgc ctccagctcc gcgccgggat actgagcgat
     2401 gactgtatgc agttgcacgc taatatcacg cgcaatcgca tccggcagat gaacgatatg
     2461 tgttttacca ttgatgtcac ggcgctccgc cccatgcacg cccgctaacg ggaagcgata
     2521 aggttttgcc agtgcgtcaa gctccaccat tgagcgccct gatatcaatg ccaatgcacc
     2581 atcacttgcg gttgccagta gctgtagtcc ttgcagaata ttgtcaggca cgacgacctg
     2641 atcgggatgc ggtttgattt ccgccagcgt tccatcaaga tcaaaaaacc aggcatattt
     2701 cgcggatagt tcaggggttt cggttaacgg ttctgtcacc cggttctcct ccttctcttt
     2761 tcttattgtg ttgcgcagaa cgcgctttac agacatgtaa gtatagacag tgtgacgggg
     2821 gtcgccattt gcaacgaaga acagccaacc gttatggcgg ttggctatgg tgggaaaaaa
     2881 cgctaaattg ttgcagaaaa aagcatcaga cagtgcgttt cgctttttgc ttgtaacggt
     2941 cgaagatcac cgctgccagc aggattaagc cgcgaaccac gtactgcgcg aaaggagaaa
     3001 tattaagcag gttcatggcg ttttccacgg tgcctaaaat taagataccc gccaccacat
     3061 atgagatttt tccgatgcca cctttcagag aaacgccacc taaaacgcag gcggagataa
     3121 caatcagctc ataaccaatc gacgtcattg gctgcccact ggtcatacgt gaagccagaa
     3181 taattccggc tatcgctgat accaggcctg agagaacaaa gataataatt ttggtgcgaa
     3241 caaccggtac acccgccaga cgcgcggcct cttcgttccc gccaatcgcc agggtgttac
     3301 gaccaaaggt ggttttattc agcagcaaac caaagataat cagacacgcg acggtgagcc
     3361 agattggcgc aggcagaccg aaccagttgg cgtaaccaag ggcaaagaag ctttcatctt
     3421 cgataccgac cgctttaccg tctgaaatga tgtacgccag acctcgaaca atctgcatcg
     3481 ttgccaatgt cgtgatcaga gcatttattt tcagtttggc gataacaaag ccattgacca
     3541 ggccacagag aacgcccagc aacaaccccg ctgccacgcc aatccacagg ctttcagtca
     3601 ggttaataac caccgccgtg gtgacacccg cacaggcaat tacggaggcg acagaaaggt
     3661 caaagtcacc ggaagcgagg cagaacaaca tgccacaagc caccatcccc gacatggaaa
     3721 ttgccaggcc caaccctttc atattaatga aggtggcaaa atttgggaca aaaatggcac
     3781 aggcgataaa gagcaccgca aacaccacca gcatgccgta ctgatcccag atacgcccga
     3841 agctgaatga cgacttaggt gcgccagacc ccgatgtaga aacagaagac atcatactct
     3901 ccttactcag gcaacagcct ggctgacttt aggcatcgca aggctcagtg cctgacgctc
     3961 atctgcctgc tcgtgtaaca attcaccggc gatttcacct tcccgcatca ccacaatccg
     4021 gtcggcaacg ccgaggactt caggtaagtc gctggaggca aacagcaccg ccacgccctg
     4081 cgccgccagc gcataaatta cgttatatat ttcgtgctta gcgccaacat caatgccgcg
     4141 cgtaggttca tccagcaaaa tgaccttcat ctcttccgat aaccagcggc ccagaatggc
     4201 tttttgctga tttccgcctg agagattcat gatcagttgc tccgcgcccg gcgttttgat
     4261 gttgagcgaa cgaatgtggt gatcggcatt gttttcttcc caaccgttgt tgattacaca
     4321 accgccgagc acatgtttac gtctggcact gatgttgata ttgtcgcgaa cggagtgcac
     4381 gggaataatg ccttccgctt tgcgatcttc cgggca
//
LOCUS       DAPGUL010000223         4387 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.227, whole genome shotgun sequence.
ACCESSION   DAPGUL010000223 DAPGUL010000000
VERSION     DAPGUL010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4387
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.227"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            16..558
                     /gene="fimA"
                     /locus_tag="RHX21_004661"
     CDS             16..558
                     /gene="fimA"
                     /locus_tag="RHX21_004661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308619.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial major subunit FimA"
                     /protein_id="HDV1989727.1"
                     /translation="MKLRFISSALAAALFAATGSYAAVVDGGTIHFEGELVNAACSVN
                     TDSADQVVTLGQYRIDIFNAVGNTSALIPFTIQLNDCDPVVAANAAVAFSGQADAIND
                     NLLAIASSTNTTTATGVGIEILDNTSAILKPDGNSFSTNQNLIPGTNVLHFSARYKGT
                     GTSASAGQANADATFIMRYE"
     gene            778..1470
                     /gene="fimC"
                     /locus_tag="RHX21_004662"
     CDS             778..1470
                     /gene="fimC"
                     /locus_tag="RHX21_004662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria chaperone FimC"
                     /protein_id="HDV1989728.1"
                     /translation="MMTKIKLLMLIIFYLIISASAHAAGGIALGATRIIYPADAQQTA
                     VWIRNSHTNERFLVNSWIENSSGVKEKSFIITPPLFVSEPKSENTLRIIYTGPPLAAD
                     RESLFWMNVKTIPSVDKNALNGRNVLQLAILSRMKLFLRPIQLQELPAEAPDTLKFSR
                     SGNYINVHNPSPFYVTLVNLQVGSQKLGNAMAAPRVNSQIPLPSGVQGKLKFQTVNDY
                     GSVTPVREVNLN"
     gene            1501..4110
                     /locus_tag="RHX21_004663"
     CDS             1501..4110
                     /locus_tag="RHX21_004663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis usher protein"
                     /protein_id="HDV1989729.1"
                     /translation="MKIPTTTDIPQRYTWCLAGICYSSLAILPSFLSYAESYFNPAFL
                     LENGTSVADLSRFERGNHQPAGVYRVDLWRNDEFIGSQDIVFESTTENTGDKSGGLMP
                     CFNQVLLERIGLNSSAFPELAQQQNNKCINLLKAVPDATINFDFAAMRLNITIPQITL
                     LSSAHGYIPPEEWDEGIPALLLNYNFTGNRGNGNDSYFFSELSGINIGPWRLRNNGSW
                     NYFRGNGYHSEQWNNIGTWVQRAIIPLKSELVMGDGNTGSDIFDGVGFRGVRLYSSDN
                     MYPDSQQGFAPTVRGIARTAAQLTIRQNGFIIYQSYVSPGAFEITDLHPTSSNGDLDV
                     TIDERDGNQQNYTIPYSTVPILQREGRFKFDLTAGDFRSGNSQQSSPFFFQGTALGGL
                     PQEFTAYGGTQLSANYTAFLLGLGRNLGNWGAVSLDVTHARSQLADDSRHEGDSIRFL
                     YAKSMNTFGTNFQLMGYRYSTQGFYTLDDVAYRRMEGYEYDYDYDGEHRDEPIIVNYH
                     NLRFSRKDRLQLNISQSLNDFGSLYISGTHQKYWNTSDSDTWYQVGYTSSWVGISYSL
                     SFSWNESVGIPDNERIVGLNVSVPFNVLTKRRYTRENALDRAYASFNANRNSNGQNSW
                     LAGVGGTLLEGHNLSYHVSQGDTSNNGYTGSATANWQATYGTLGVGYNYDRDQHDVNW
                     QLSGGVVGHENGITLSQPLGDTNVLIKAPGAGGVRIENQTGILTDWRGYAVMPYATVY
                     RYNRIALDTNTMGNSIDVEKNISSVVPTQGALVRANFDTRIGVRALITVTQGGKPVPF
                     GSLVRENSTGITSMVGDDGQVYLSGAPLSGELLVQWGDGANSRCIAHYVLPKQSLQQA
                     VTVISAVCTHPGS"
     gene            4123..>4387
                     /locus_tag="RHX21_004664"
     CDS             4123..>4387
                     /locus_tag="RHX21_004664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308622.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV1989730.1"
                     /translation="MKIICRLLLAMACLCLANISWATVCANSTGVAEDEHYDLSNIFN
                     STNNQPGQIVVLPEKSGWVGVSAICPPGTLVNYTYRSYVTNFIV"
BASE COUNT         1169 a          957 c         1036 g         1225 t
ORIGIN      
        1 attgaaggaa tatatatgaa attaagattt atttcgtctg cgctggctgc cgcactattc
       61 gccgctacgg gtagttatgc tgccgttgta gatggcggta caattcactt tgaaggcgaa
      121 ctggtgaatg ctgcctgttc agtgaatact gactcggcag accaggttgt cacactcggt
      181 caatatcgta tcgatatttt caatgctgtt ggtaatacct ctgcattaat tccattcacc
      241 attcagttga acgactgcga tcctgttgtt gccgctaatg ctgccgttgc attttctggt
      301 caggctgatg caatcaatga taatttattg gccattgcat ccagtaccaa tacaacaaca
      361 gcaacgggtg tcggtattga aatacttgat aatacatccg caattctcaa acctgatggg
      421 aatagcttct caaccaacca gaacttgatc cccgggacca acgttcttca tttttctgca
      481 cgttataaag gcaccggtac aagtgcatca gcagggcaag caaatgctga cgcgactttt
      541 attatgagat acgaataatc aaaaccacgt tgttttgaat tatatatcac gtcttataac
      601 aaagtaatgt accggttgtc tgaagcggta tggtggcaat gtaaatcgaa atcatgttca
      661 ctttgtatca tgccgcttta ttaaatgaaa agggaatgat gtgttgtaag aaaccaaagc
      721 aatcatttct ttatatttct tatttttgcc gtcaggaata cacaaggcgt attaactatg
      781 atgactaaaa taaagttatt gatgctcatt atattttatt taatcatttc ggccagcgcc
      841 catgctgccg gagggatcgc attaggtgcc acgcgtatta tttatcccgc tgatgctcaa
      901 cagactgcgg tatggattag aaatagccat accaatgagc gctttctggt caattcgtgg
      961 attgaaaaca gcagcggtgt aaaagaaaag tcattcatca ttacaccgcc actgtttgtt
     1021 agtgaaccca aaagcgaaaa taccttgcgt attatttaca ccggtccacc gctggcggca
     1081 gatcgtgagt ctctgttctg gatgaatgtt aagacgatcc cttcggtaga taaaaatgca
     1141 ttgaacggca ggaatgtttt gcaactggcg attttatcgc gcatgaaatt atttctccgt
     1201 ccaattcaat tacaagaatt acccgcagaa gcgccggaca cactcaagtt ttcgcgatcc
     1261 ggtaactata tcaatgttca taatccctca cctttttatg tcaccctggt taacttacaa
     1321 gtgggcagcc aaaagttggg gaatgctatg gctgcaccca gagttaattc acaaattccc
     1381 ttaccctcag gagtgcaggg aaagctgaaa tttcagaccg ttaatgatta tggttcagta
     1441 accccggtca gagaagtgaa cttaaactaa ccgaatcatc tgacaatatc agagctaatt
     1501 atgaaaatac ccactactac ggatattccg cagaggtata cctggtgtct ggccggaatt
     1561 tgttattcat ctcttgccat tttaccctcc tttttaagct atgcggaaag ttatttcaac
     1621 ccggcatttt tattagagaa tggcacatcc gttgctgatt tatcgcgctt tgagagaggc
     1681 aatcatcaac ctgcgggagt gtatcgggtg gatctctggc gtaatgatga gttcattggt
     1741 tcacaggata tcgtatttga atcgacaaca gaaaatacag gtgataaatc aggtgggtta
     1801 atgccctgtt ttaaccaggt actccttgaa cgaattggcc ttaatagcag tgcatttccc
     1861 gagttagccc agcagcaaaa caataaatgc atcaatttac tgaaagctgt acctgatgcc
     1921 acaattaact ttgattttgc agcgatgcgc ctgaacatca ctattcctca gataacgttg
     1981 ttgagtagcg ctcacggtta cattccgcct gaagagtggg atgaaggtat tcctgcttta
     2041 ctcctgaatt ataatttcac cggtaacaga ggtaatggta acgatagcta tttttttagt
     2101 gagctcagcg ggattaatat tggcccgtgg cgtttacgca acaatggttc ctggaactat
     2161 tttcgcggaa atggatatca ttcagaacag tggaataata ttggcacctg ggtacagcgc
     2221 gccattattc cgctgaaaag tgaactggta atgggagacg gcaatacagg aagtgatatt
     2281 ttcgatggtg ttggatttcg tggtgtacgg ctttattctt ccgataatat gtatcctgat
     2341 agccagcaag ggtttgcccc aacggtacgt gggattgccc gtacggcggc ccagctaacg
     2401 attcggcaaa atggttttat tatctatcaa agctatgttt cccccggcgc ttttgaaatt
     2461 acagatttgc acccgacatc ttcaaatggc gatctggacg tcaccatcga cgagcgcgat
     2521 ggtaatcagc agaattacac tatcccgtat tcaacagtgc caattttaca acgcgaaggg
     2581 cgtttcaaat ttgacctgac ggcgggcgat tttcgtagcg gtaatagtca gcaatcatcg
     2641 cctttctttt ttcagggcac ggcactcggc ggtttaccac aggaatttac tgcctacggc
     2701 gggacgcaat tatctgccaa ttacaccgcc tttttattag ggctggggcg caacctcggg
     2761 aactgggggg cagtgtcgct ggatgtgacc catgcgcgca gtcagttagc cgacgacagt
     2821 cgtcatgagg gggattccat tcgcttcctc tatgcgaaat cgatgaacac cttcggcacc
     2881 aattttcagt taatgggtta ccgctattcg acacaaggtt tttataccct tgatgatgtt
     2941 gcgtatcgtc gaatggaggg gtacgaatat gattacgatt acgacggtga gcatcgcgat
     3001 gaaccgataa tcgtgaatta ccacaattta cgctttagcc gtaaagaccg tttgcagtta
     3061 aatatttcac aatcacttaa tgactttggc tcgctttata tctctggtac ccatcaaaaa
     3121 tactggaata cttcggattc agatacctgg tatcaggtgg ggtataccag cagctgggtt
     3181 ggcatcagtt attcgctctc attttcgtgg aatgaatctg tagggatccc cgataacgaa
     3241 cgtattgtcg gacttaatgt ttcagtgcct ttcaatgttt tgaccaaacg tcgctacacc
     3301 cgggaaaatg cgctcgaccg cgcttatgcc tcctttaacg ccaaccgtaa cagcaacggg
     3361 caaaatagct ggctggcagg tgtaggtggg accttactgg aaggccacaa cctgagttat
     3421 cacgtaagcc agggtgatac ctcgaataat gggtatacgg gcagcgccac ggcaaactgg
     3481 caggccactt acggtacgct gggggtcggg tataactacg accgcgatca acatgacgtt
     3541 aactggcagc tgtctggcgg tgtggtcggg cacgaaaatg gcataacgct gagccagcct
     3601 ttaggggata ccaatgtttt gattaaagcg cctggcgcag gcggtgtacg cattgaaaat
     3661 caaactggca ttttaaccga ctggcgcggc tatgcggtga tgccgtatgc cacggtttat
     3721 cggtataacc gtatcgcgct tgataccaat acgatgggga attccatcga tgttgaaaaa
     3781 aatattagca gcgttgtgcc gacgcaaggc gcgttggttc gtgccaattt tgatacccgc
     3841 ataggcgtgc gggcgctcat taccgttacc cagggcggaa aaccggtgcc gtttggatca
     3901 ctggtacggg aaaacagtac cggaataacc agtatggtgg gtgatgacgg gcaagtttat
     3961 ttaagtggtg cgccattgtc tggtgaatta ctggttcagt ggggagacgg cgcgaactca
     4021 cgctgcattg cgcactatgt attgccgaag caaagcttac agcaagccgt cactgttatt
     4081 tcggcagttt gcacacatcc tggctcataa aggaaattat caatgaagat aatctgcaga
     4141 ttattattgg cgatggcatg tttgtgtctg gcaaacatat cctgggctac tgtttgtgca
     4201 aatagtactg gcgtagcaga agatgaacac tatgatctct caaatatctt taatagcacc
     4261 aataaccagc cagggcagat tgttgtttta ccggaaaaat ccggctgggt aggtgtgtca
     4321 gcaatttgtc cacccggcac gctggtgaat tatacatacc gtagttatgt caccaacttt
     4381 attgttc
//
LOCUS       DAPGUL010000224         4315 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.228, whole genome shotgun sequence.
ACCESSION   DAPGUL010000224 DAPGUL010000000
VERSION     DAPGUL010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4315
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.228"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(164..677)
                     /locus_tag="RHX21_004665"
                     /pseudo
     CDS             complement(164..677)
                     /locus_tag="RHX21_004665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001566943.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4113 domain-containing protein"
     gene            complement(738..842)
                     /locus_tag="RHX21_004666"
                     /pseudo
     CDS             complement(738..842)
                     /locus_tag="RHX21_004666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544830.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            complement(844..1167)
                     /locus_tag="RHX21_004667"
                     /pseudo
     CDS             complement(844..1167)
                     /locus_tag="RHX21_004667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000952428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1910..2887
                     /locus_tag="RHX21_004668"
     CDS             1910..2887
                     /locus_tag="RHX21_004668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052630.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDV1989731.1"
                     /translation="MDKSSGELVTLTPNNNNTVQPVALMRLGVFVPTLKSLKNSKKNT
                     LSRTDATEELTRLSLARAEGFDKVEITGPRLDMDNDFKTWVGIIHSFARHNVIGDKVE
                     LPFVEFAKLCGIPSSQSSRRLRERISPSLKRIAGTVISFSRTDEKHTREYITHLVQSA
                     YYDTERDIVQLQADPRLFELYQFDRKVLLQLKAINALKRRESAQALYTFIESLPRDPA
                     PISLARLRARLNLKSPVFSQNQTVRRAMEQLREIGYLDYTEIQRGRTKLFCIHYRRPR
                     LKAPNDESKENPLPPSPAEKVSPEMAEKLALLEKLGITLDDLEKLFKSR"
     gene            complement(3166..3906)
                     /locus_tag="RHX21_004669"
     CDS             complement(3166..3906)
                     /locus_tag="RHX21_004669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDV1989732.1"
                     /translation="MNNVIPLQNSPERVSLLPIAPGVDFATALSLRRMATSTGATPAY
                     LLAPEVSALLFYMPDQRHHMLFATLWNTGMRIGEARMLTPESFDLDGVRPFVRILSEK
                     VRARRGRPPKDEVRLVPLTDISYVRQMESWMITTRPRRREPLWAVTDETMRNWLKQAV
                     RRAEADGVHFSIPVTPHTFRHSYIMHMLYHRQPRKVIQALAGHRDPRSMEVYTRVFAL
                     DMAATLAVPFTGDGRDAAEILRTLPPLK"
     gene            complement(4027..4215)
                     /locus_tag="RHX21_004670"
     CDS             complement(4027..4215)
                     /locus_tag="RHX21_004670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001309252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HDV1989733.1"
                     /translation="MASDTFSCRRRLSAGFFSVSACSWHYPNSPKNGKPVLSPHHDWL
                     KTGSLRQNAPLRIWFYPQ"
BASE COUNT         1039 a         1091 c         1063 g         1122 t
ORIGIN      
        1 gctttttcgg ttgaaaagaa attgattgaa ttactggaaa aacaatctgg tctccatacg
       61 tctgtggatt gcagtactcc ccttacagag cagagtctgt cgagaaatga cggtgaagac
      121 cagaccagaa gaaacgctga aaatatgttc ggagatgact gaactaaccc agcctggcca
      181 ggggaatatc tcgccattta gttgtataac actgactcaa catttcccgt ttcatttgcc
      241 attcaggggc ggttcctcgc cccgcaaacc acactttccc ttttcccgac tggttcagtt
      301 catcgagtgt tttcattaac ttttcactgt ttttacgggg ctggatttca tcaaataatc
      361 ccggctgcgc tatacccgat ggtgtgaaat cagccagcat gactcctgcc ttcatatagc
      421 ggtacccttc acgccagaca tggtttaagg ctctgcatgc ggcggcaata atgtcccggc
      481 tgtcctgtgt gggcaatgaa agcttttcca cagcggcatt gctgtaacag ggttcagggg
      541 gatgtccgta caaatgtcgt cacctgccgg caatactgac gctccccacg tagtttctct
      601 gcggcccgct ctgcatactg aacaacagcc tggtgcatgg catctttgtc tgtgattcgt
      661 tcaccaaaac tgcgactatg tcaacgccac gatgtttgac cgttatttgc cattttcatg
      721 cccgctaaat actttcgtta ctgatgctgt ccgctttgca ccatttcatc atcactgatt
      781 ggcgttgtgt ttttggtcag cactccagct ttacgtttct cttttaaccg gtaactctct
      841 ccttgttctt tttgacggac gcattttacg tttgggctgg atgtagtaac gcagcatgga
      901 acgtccgccc gtataaccca ttgccttaat ctccgcgaag ataacctcgc tattccagac
      961 attctctgcc aggcgcatgt cgatgtaatc cataaacggt ttcagcttaa ccattttgtg
     1021 gcgggtcttt ctggctggcg gttcagggta tttgaggtag cgtctgaccg tccgttcaga
     1081 gcaaccaatc tgagccgcaa tatcgacaat gtacgcgccc tgctggcgca tttgctttat
     1141 catgtaaaag tcctctctgc tcagcatgtt gatgtccttt ctggtgtgag aaccttaagg
     1201 aaacaacatg ttgggtggag cggacaatcc aaatggtgaa ttaccgtctt atatcactgg
     1261 cgctgacacc tgtagtttgt atacacaatc cctggcattg aaacacacat atgaagtgta
     1321 cttcggatat gaccgtacgc tcaggaagta cggcagattc cgtcaaaaat tacctgtaaa
     1381 gacagacatc agaaaaaaca gtgctcgccg cagaccggtg accgggcgaa gcccgcgaac
     1441 cggcgaggaa gcgcaatgga tctgtagtta cagtgagcag gtacgccctg aagccttcat
     1501 aatcggtagt gtatgctgtt tttctggaat gatttatcca catatccaga ggcccgatcc
     1561 agtaaacaga tccatgaatg atcaacaaag gatccattaa agatccccat atcgctgtca
     1621 accttgtcac tcatgggccg ggaccacgtt cacataagcg gtggcatgtt atggataaac
     1681 tgtaacaggt tcatgataag ctgtattcag taatgcatat actgaagtaa gttaatgaca
     1741 taaactatgg tcagtacgcc agactcagtt gttaaataca gactgcaggt ttttcttcag
     1801 tcagttgacg gggttctgac acacgatttt ctgtttattc ttttactgtc cacaggcagg
     1861 aggctttctg gaaaacgaaa attcagacat caaaaaactg ttcggcgagg tggataagtc
     1921 gtccggtgag ctggtgacac tgacaccaaa caataacaac accgtacaac ctgtggcgct
     1981 gatgcgtctg ggcgtctttg taccgaccct taagtcactg aagaacagta aaaaaaatac
     2041 actgtcacgc accgatgcca cggaagaact gacacgtctt tccctggccc gtgcagaagg
     2101 attcgataag gttgagatca ccggcccccg gctggatatg gataacgatt tcaagacctg
     2161 ggtggggatc attcattcct ttgcccgcca taacgtgatt ggtgacaaag ttgaactgcc
     2221 ttttgttgag tttgcaaaac tgtgtggtat accttcaagc cagtcatccc gcaggctgcg
     2281 tgagcgcatc agcccttccc tgaagcgcat tgccggtacc gtgatctcgt tttcccgtac
     2341 cgatgagaag cacacccggg aatacatcac ccatctggta cagtcagcct actacgatac
     2401 tgagcgggat attgtgcagt tacaggccga tccccgcctg tttgaactgt accagtttga
     2461 cagaaaagtc cttctccagc ttaaggcgat taatgccctg aagcgacggg agtccgccca
     2521 ggcactctac acctttatag agagcctgcc ccgggatccg gcaccgatat cgctggcgcg
     2581 gctgcgtgca cgcctcaatc tgaagtctcc tgtattttcc cagaaccaga cggtcagacg
     2641 ggcaatggag cagctgcgcg agattggata tcttgattac acggagatcc agcgggggcg
     2701 gacaaaactc ttctgcattc actaccggcg tccccggtta aaagcaccga atgatgagag
     2761 taaggaaaat ccgttgccac cttcacctgc ggaaaaagtc agtccggaga tggcggagaa
     2821 gcttgccctg cttgaaaaac tgggcatcac gctggatgac ctggaaaaac tcttcaaatc
     2881 ccgctgaaca taaactgtag tcagtgaaga gtgctccttt actgactaca gcttatatta
     2941 tcaggtgcag tgagtggtct gctcactgca gtttatattc agtttcatgc agtgctgcct
     3001 gtggctgagc tgccatctgc ctgtccctta cgtgagtcac cccgtaacct gatgctgagg
     3061 cattgctccc ttcataaaac atggtttact cactacagct tatctacctg ctccagctta
     3121 tgttatgtct gttctgctga ccactgctta tataaggagg tgccgttact tcaggggagg
     3181 cagtgtacgc aggatctccg cagcatcccg cccgtcacct gtgaaaggca ctgccagcgt
     3241 ggctgccata tccagtgcaa acactctggt ataaacctcc atagaacgtg gatccctgtg
     3301 accagccagt gcctggatga ctttccgggg ctggcggtga tagagcatgt gcatgatata
     3361 gctgtgccgg aaggtgtgtg gtgtgaccgg aatcgaaaag tgtactccgt cagcttcggc
     3421 ccgtctgaca gcctgcttca gccagttgcg catggtttcg tcggtcacgg cccataatgg
     3481 ttcacgacga cggggccggg tggtgatcat ccagctttcc atctgcctga catagcttat
     3541 atccgtcagc ggaaccaggc ggacttcatc ttttggcggg cgtccgcgtc gcgcacgcac
     3601 tttttcggac aggatccgca caaacggtct tactccatcc aggtcaaatg attccggtgt
     3661 cagcatccgg gcttcgccaa tacgcattcc ggtattccag agggtggcga acagcatatg
     3721 gtgacgctga tccggcatat agaaaagaag ggcactcact tccggggcca gcaggtaggc
     3781 cggtgtggcc cctgtggaag tggccattct tctcagggag agcgctgttg caaaatccac
     3841 ccccggcgca atgggtaaca gggagacgcg ttctggtgaa ttctgcaggg gaatgacatt
     3901 gttcatgagt tatttttcac gtagcacacg cactgtttat ggatacaggt attctgacct
     3961 gaacgcccgg atccttccac gacaataaat cgcagcgcgc ggatcctttt gtttgcttat
     4021 cacgcattat tgcgggtaaa accaaatacg taaaggcgcg ttttgccgca gggatcctgt
     4081 cttaagccag tcatggtgcg ggctgaggac tggtttgccg tttttgggag aattggggta
     4141 atgccaggaa caggcagata cggagaaaaa tcctgcagat aaccttctac gacaactgaa
     4201 ggtgtctgac gccatattct tagctacttc tcagttttaa ggcggcttag tcacaacata
     4261 aggttatgca taataagcat attttattat gttatgttat ggtcttgttc atgca
//
LOCUS       DAPGUL010000225         4222 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.229, whole genome shotgun sequence.
ACCESSION   DAPGUL010000225 DAPGUL010000000
VERSION     DAPGUL010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4222)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4222)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4222
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.229"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(309..461)
                     /locus_tag="RHX21_004671"
     CDS             complement(309..461)
                     /locus_tag="RHX21_004671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989734.1"
                     /translation="MPSMIAIILLIILHIWLCRQDGDHFWSESRLNISLLMLEVKHLA
                     RGKGLR"
     gene            complement(449..916)
                     /locus_tag="RHX21_004672"
     CDS             complement(449..916)
                     /locus_tag="RHX21_004672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HDV1989735.1"
                     /translation="MSRVTAIISALVICIIVCLSWAVNHYRDNAIAYKEQRDKKVREL
                     KQATATITDMQQRQRSADALDAKYTKELADAKAENDALRRKLDNGGRVFVKGKCPVPS
                     SAETSSASGMGNDATVELSPVAGRNVLGIRDGIIRDQTALRTLQEYIRTQCLR"
     gene            complement(913..1410)
                     /gene="rrrD"
                     /locus_tag="RHX21_004673"
     CDS             complement(913..1410)
                     /gene="rrrD"
                     /locus_tag="RHX21_004673"
                     /EC_number="3.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme RrrD"
                     /protein_id="HDV1989736.1"
                     /translation="MPPSLRKAVAAAIGGGAIAIASVLITGPSGDDGLEGVSYIPYKD
                     IVGVWTVCHGHTGKDIMLGKTYTEAECKALLNKDLATVARQINPYIKVDIPETTRGAL
                     YSFVYNVGAGNFRTSTLLRKINQGDIKGACDQLRRWIYAGGKQWKGLMTRREIEREVC
                     LWGQQ"
     gene            complement(1410..1625)
                     /gene="essD"
                     /locus_tag="RHX21_004674"
     CDS             complement(1410..1625)
                     /gene="essD"
                     /locus_tag="RHX21_004674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage lysis protein EssD"
                     /protein_id="HDV1989737.1"
                     /translation="MKSMDKLTTGVAYGTSAGSAGYWFLQLLDKVTPSQWAAIGVLGS
                     LVFGLLTYLTNLYFKIKEDKRKAARGE"
     gene            complement(1693..2745)
                     /locus_tag="RHX21_004675"
     CDS             complement(1693..2745)
                     /locus_tag="RHX21_004675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HDV1989738.1"
                     /translation="MKNTVKINSVDLINADCLHFIQSLPDDSIDLIVTDPPYFKVKPN
                     GWDNQWKGDEDYLKWLDHCLAQFWRVLKPAGSLYLFCGHRLASDIEIMMRERFNVLNH
                     IIWAKPSGRWNGCNKESLRAYFPATERVLFAEHYQGPYRGKSDGYAAKERELKQHIMA
                     PLISYFRDARAELGITAKQIAEATGKKNMVSHWFGASQWQLPNEADYRKLQALFSRIA
                     AEKFQEQQLEQPHHQLVASYDSLNRKYSELLDEFKSLRRYFSVSVSVPYTDVWMHKPV
                     QFYPGKHPCEKPADMLRQIINASSRPGDLVADFFMGSGSTIKAAMALGRRALGVELES
                     ERFNQTVKEINELVGK"
     gene            complement(2895..3089)
                     /locus_tag="RHX21_004676"
     CDS             complement(2895..3089)
                     /locus_tag="RHX21_004676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309806.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HDV1989739.1"
                     /translation="MLKQQDMTETAKVVFNELSIEPATVGEIAQNTYLSRERCQLILT
                     QLVMAGLADYQFGCYRRLQQ"
     gene            3338..>4222
                     /locus_tag="RHX21_004677"
     CDS             3338..>4222
                     /locus_tag="RHX21_004677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001564338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HDV1989740.1"
                     /translation="MTTLKELKEELAQIQDEHAKNRKKAEIAALTASADNEIRLAQRN
                     IGYNVREWTVEVIIQKYGDNIENDKNELFIPDYQRDYKWDTKTASRFIESILLDFPIP
                     YLYIADVFNEDPELDGRVEIIDGSQRIRSIYYFWNDQFELKDLKELKSLEGFKFSDLL
                     ASRQRRFLRASLRFIELKGDVEEQHRRDLFERINSGVKRLEAMEVRHGSDAATSMFYK
                     DVVTPCSTNSLFSQLAPLSDRKRSNGDHRELVLRFFAYLNDLENYKGFVRPFIDNYLN
                     EQAAAVTTQQDVDNFKHDF"
BASE COUNT         1151 a          979 c          919 g         1173 t
ORIGIN      
        1 tattatccct tatatgttaa aagtaatgaa tgaaaaagga aaagttgctt tccagccagc
       61 atggttccct gagaacgata atcatgaaga aactttcgat tctctttgcg agttataccg
      121 tgaaggaaaa atcacaatgg aaggaggtta ttacttcgat ctaattttta tcctgtaatc
      181 tgactatcaa aagtattatc gcaggcactc agtgaatgcc tgcggtaatg ccgttcgtga
      241 taagcgaggt taacaaacca ttatcaagcc catccgtaga taggctttgt aatgaactgg
      301 ctcttatctc aacgcagccc cttaccgcgc gccagatgtt taacctcaag catcagcaat
      361 gagatgttta atctggattc actccagaag tgatcaccat cctgtctaca gagccagatg
      421 tgaaggatga tgagtaaaat tatcgctatc atcgaaggca ttgcgtcctg atgtattcct
      481 gaagcgttct cagtgctgtt tggtcgcgga taattccgtc ccggataccg agaacgtttc
      541 gtccagcaac tggagagagt tcgacggtgg catcattgcc catgccggag gcgctggagg
      601 tttcggctga ggatggcaca gggcattttc ctttgacgaa cacccgacca ccattatcaa
      661 gcttgcgccg aagagcatca ttttcagctt tcgcatcagc taactccttc gtgtatttag
      721 catcgagtgc atcagcagaa cgctggcgct gctgcatgtc agtaatggtg gcggtcgcct
      781 gcttcagctc tctgactttt ttatctcgct gttctttgta ggcgatggcg ttatcacggt
      841 aatgattgac cgcccacgac aggcagacga tgatgcagat aaccagagcg gagataatcg
      901 cggttactct gctcattgtt gcccccacaa acagacttca cgctcaatct cacgacgagt
      961 catcaggcct ttccattgct taccgccagc gtatatccag cgacgtagct ggtcacatgc
     1021 gcctttgata tcgccctggt ttattttgcg aagaagcgtc gatgttctga aattgccagc
     1081 acccacgttg tagacgaacg agtacagagc gccgcgcgtt gtttccggta tatcgacttt
     1141 gatgtacggg ttaatttgtc tggcaaccgt ggcaaggtct ttattcagga gggctttgca
     1201 ttctgcttcg gtatacgttt taccgagcat gatgtctttt ccggtgtgtc cgtgacatac
     1261 agtccatacg ccaacgatat ctttgtatgg tatgtagctg acaccttcca ggccatcgtc
     1321 accacttggg ccagtgatta acactgatgc tatagcaatt gctccgccac caatagcagc
     1381 agcaactgct tttcgtaatg atggaggcat tattcacctc tcgcagcctt gcgcttatct
     1441 tctttaatct tgaaataaag gtttgtcagg tacgtcagca ggccaaatac cagactaccc
     1501 agcacaccta ttgccgccca ctgtgagggc gtgactttat cgagcaactg taaaaaccag
     1561 tacccggcac tacctgctga ggtgccatag gcgacacccg ttgttaactt atccatggat
     1621 ttcataaccc cacctcgcag atgcgggtgc tgtgtaatgg aaataaaaag gccacctgac
     1681 gtggccacca gattatttcc ccaccagctc gtttatctct ttcactgtct ggttaaaccg
     1741 ctctgactca agctcaacac ctaaggcccg acgccccagc gccattgctg cttttattgt
     1801 ggaaccggat cccataaaaa aatcagcaac cagatcacca ggtcgactac tggcattgat
     1861 tatttgcctg agcatatccg ccggtttctc acacggatgt ttacccgggt agaactgaac
     1921 gggtttatgc atccagacat cggtataagg cacggagact gatacggaga aatagcgccg
     1981 gagagattta aactcatcca gcaattcaga atatttgcga ttcagtgaat cataagatgc
     2041 caccagctgg tggtgtggtt gttccagttg ttgttcctga aacttctctg ccgctatacg
     2101 ggaaaacagt gcctgtaact tccgatagtc agcctcattc ggcaactgcc actgactggc
     2161 accaaaccag tgggaaacca tatttttctt acctgtggct tcggcaattt gttttgccgt
     2221 tatacccagt tcggcacgag catccctgaa atacgatatc agcggtgcca ttatgtgctg
     2281 tttgagttcc ctttcttttg ccgcatagcc gtcacttttg ccgcgatatg gcccctggta
     2341 atgttcagca aacagaacgc gctctgtggc aggaaaatat gcgcgcagac tttctttatt
     2401 acacccattc caacgtccgg acggcttcgc ccagatgata tggttaagca cgttgaaacg
     2461 ttcacgcatc atgatctcaa tatcagatgc caggcgatgc ccacagaaca ggtaaaggct
     2521 tccggcaggt ttcaacaccc gccagaactg ggccagacag tggtccagcc acttaaggta
     2581 atcttcgtcc cctttccact gattgtccca accgttgggt ttcaccttga agtaaggcgg
     2641 atcggtaaca atcaggtcaa tggaatcatc aggcagggac tgaataaaat gcaggcaatc
     2701 agcgttgatt aaatcaacac tgtttatttt tacagtattt ttcatggatc agtaagcgta
     2761 actctggtag gctcactctg cttttgcgct aaagcagtgg gccgtggttc gcttgtgacc
     2821 agtaagcatg agcgaatggc tggcaggtgc taccaacacc caccagccgc ccattttcac
     2881 aaattaaaag tccttcattg ctgaaggcgt ctgtaacagc cgaactggta atctgccagc
     2941 cccgccataa ccaactgggt cagtattaac tgacagcgtt cgcgtgaaag atatgtgttt
     3001 tgtgcaatct ccccgactgt tgccggttcg atgcttaatt cattaaaaac aactttcgcc
     3061 gtttctgtca tatcttgctg ttttagcatg tcttttttcc ttctggttaa catgacatac
     3121 caataactct tgtctaaaaa gccagcaaga taaaaagtca gtattcacga ccaccagcgt
     3181 gtttaccgta ctgcaccagg tttacaggta caaaaaaacc cgctcgacgg cgggtttaag
     3241 ttgtgtggcg aagtaaccac tcttaacaca atacaatact ttttgcgtac gcgttatagt
     3301 tttcttacaa tcaactttca attaaaggaa cgaaaacatg actacactca aagaactcaa
     3361 agaagagctt gctcagatac aagatgaaca cgctaagaac agaaaaaagg ctgaaattgc
     3421 agctttaacc gcttccgctg acaatgaaat cagactcgct cagagaaaca ttggatacaa
     3481 tgtacgtgag tggaccgttg aagtcattat tcaaaagtat ggtgataata ttgaaaatga
     3541 caaaaacgag ctttttattc cagattatca acgtgattac aagtgggata caaaaacagc
     3601 ctctcgcttt atagaaagta ttctattaga ctttccaata ccttaccttt acattgctga
     3661 tgtatttaat gaagaccctg aattagatgg tagggtagaa atcattgatg gttcacaacg
     3721 gatacgctct atttattatt tttggaacga tcaatttgag ttaaaggatt tgaaagagct
     3781 taaaagttta gaaggtttca aattttcaga tcttttagct agccgccaaa gaagattttt
     3841 aagagcttca ctaagattta ttgagttgaa aggtgatgtt gaggaacaac atagaagaga
     3901 tttatttgaa aggatcaact caggtgttaa aagattagaa gcgatggaag tgaggcatgg
     3961 ctcagatgct gctacctcaa tgttctataa agatgttgtg accccatgct caacaaactc
     4021 acttttttcc caactagctc cattatcaga ccggaaacgg tcgaatggcg atcatcgtga
     4081 gttagttttg agattttttg catatttaaa tgatttagaa aactataagg gatttgtccg
     4141 tccctttatt gataattatt taaatgaaca agcagcagct gtgactactc aacaagatgt
     4201 tgataatttt aaacatgatt tt
//
LOCUS       DAPGUL010000226         4211 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.230, whole genome shotgun sequence.
ACCESSION   DAPGUL010000226 DAPGUL010000000
VERSION     DAPGUL010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4211)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4211)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4211
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.230"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            309..917
                     /locus_tag="RHX21_004678"
     CDS             309..917
                     /locus_tag="RHX21_004678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase"
                     /protein_id="HDV1989741.1"
                     /translation="MKLVGSYTSPFVRKLSILLLEKGITFEFINELPYNADNGVAQFN
                     PLGKVPVLVTEEGECWFDSPIIAEYIELMNVAPAMLPRDPLESLRVRKIEALADGIMD
                     AGLVSVREQARPAAQQSEDELLRQREKINRSLDVLEGYLVDGTLKTDTVNLATIAIAC
                     AVGYLNFRRVAPGWCVDRPHLVKLVENLFSRESFARTEPPKA"
     gene            1015..2406
                     /gene="selA"
                     /locus_tag="RHX21_004679"
     CDS             1015..2406
                     /gene="selA"
                     /locus_tag="RHX21_004679"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HDV1989742.1"
                     /translation="MTTETRSLYSQLPAIDRLLRDSSFLSLRDTYGHTRVVELLRQML
                     DEAREVIRGSQTLPAWCENWAQEVDARLTKEAQSALRPVINLTGTVLHTNLGRALQAE
                     AAVEAVAQAMRSPVTLEYDLDDAGRGHRDRALAQLLCRITGAEDACIVNNNAAAVLLM
                     LAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHANDYRQAVNEN
                     TALLMKVHTSNYSIQGFTKAIDEAELVALGKELDVPVVTDLGSGSLVDLSQYGLPKEP
                     MPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPLKRALRADKMTLAAL
                     EATLRLYLHPEALSEKLPTLRLLTRSAEVIQIQAQRLQAPLAAHYGAEFAVQVMPCLS
                     QIGSGSLPVDRLPSAALTFTPHDGRGSHLESLAARWRELPVPVIGRIYDGRLWLDLRC
                     LEDEQRFLEMLLK"
     gene            2403..>4211
                     /gene="selB"
                     /locus_tag="RHX21_004680"
     CDS             2403..>4211
                     /gene="selB"
                     /locus_tag="RHX21_004680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HDV1989743.1"
                     /translation="MIIATAGHVDHGKTTLLQAITGVNADRLPEEKKRGMTIDLGYAY
                     WPQPDGRVPGFIDVPGHEKFLSNMLAGVGGIDHALLVVACDDGVMAQTREHLAILQLT
                     GNPMLTVALTKADRVDEARVNEVERQVKEVLREYGFAEAKLFITAATEGRGIDALREH
                     LLQLPEREHASQHSFRLAIDRAFTVKGAGLVVTGTALSGEVKVGDSLWLTGVNKPMRV
                     RALHAQNQPTETANAGQRIALNIAGDAEKEQINRGDWLLADVPPEPFTRVIVELQTHT
                     PLTQWQPLHIHHAASHVTGRVSLLEDNLAELVFDTPLWLADNDRLVLRDISARNTLAG
                     ARVVMLNPPRRGKRKPEYLQWLASLARAQSDADALSVHLERGAVNLADFAWARQLNGE
                     GMRELLQQPGYIQAGYSLLNAPVAARWQRKILDTLATYHEQHRDEPGPGRERLRRMAL
                     PMEDEALVLLLIEKMRESGDILSHHGWLHLPDHKAGFSEEQQAIWQKAEPLFGDEPWW
                     VRDLAKETGTDEQAMRLTLRQAAQQGIITAIVKDRYYRNDRIVEFANMIRDLDQECGS
                     TCAADFRDRLGVGRKLAIQILEYFDRIGFTRRRGNDH"
BASE COUNT          940 a         1078 c         1235 g          958 t
ORIGIN      
        1 cgcaccccgg ctgaaccctg aacaatgcta ccgccatact gcgtcatgtc gccctgacgc
       61 gctgccggtt ttccgctcat ctgctcatcc ttgttttatc gggttatttg tctgcttcca
      121 ggcaaaaccc tacagattta taagaaagcc ttaagtgaga tatccatcag atagaaacaa
      181 ttaggaaaat atttatatca ccatgataaa tatgtgattt atttggaagt aacaaaccat
      241 caacattttc tgcccttttt cccatcacca ggccatactg atatttttcc tcgcacaaag
      301 gactcggcat gaaactcgtc ggtagctaca ccagcccgtt tgtacgcaaa ctttctattc
      361 tgttgttaga aaagggcata actttcgaat ttattaatga actgccctat aacgcggaca
      421 acggcgtggc gcaatttaac ccgttaggaa aagtgccggt gctggtgacc gaagagggcg
      481 aatgttggtt tgattcgccg atcatcgctg aatatattga attaatgaat gtcgctccgg
      541 cgatgttgcc gcgcgatccg ctggagtcgt tgcgggtgcg caaaattgag gcactggcgg
      601 atggcattat ggatgccggg ctggtatcgg tgcgtgaaca ggcgcgtcca gcggcgcagc
      661 agtctgaaga tgaattgtta cgccagcggg agaaaatcaa ccgcagtctg gatgtgctgg
      721 aaggatatct ggtcgatggc acactcaaaa ccgatacggt caatctggcg actatcgcca
      781 ttgcctgtgc cgtcggatat ctcaatttcc gccgcgttgc gccaggctgg tgtgtcgatc
      841 gcccacactt agtcaaactg gtcgaaaacc tgtttagccg cgaaagtttt gctcgcaccg
      901 aaccgccaaa ggcttgatgc gcgatatgtc ctcctgaccc atctcacgtt acaatccgtg
      961 gttatgttaa acgcccttct ccgtgtgaga gggccttgat cagccaggtt tcctatgaca
     1021 accgaaacgc gttccctcta tagtcaactt ccggctattg atcgcttatt gcgcgatagc
     1081 tccttccttt ctttgcgtga tacttatggt cacacccgcg tggtggaatt gttgcgtcag
     1141 atgctcgacg aagcgcgaga agtgattcgt ggcagccaga cgctgcctgc gtggtgtgaa
     1201 aactgggcgc aagaagtcga tgcccggttg acgaaagaag cgcagagcgc gctgcgtccg
     1261 gtgatcaacc tgacgggaac cgtgctgcat accaaccttg ggcgagcttt acaggcggaa
     1321 gccgcggtgg aagccgttgc gcaggctatg cgttcgccag tgaccctcga gtacgatctg
     1381 gacgacgctg gacgcggaca tcgcgatcgt gcgctggcgc agttgctgtg ccgcattacg
     1441 ggggcggaag atgcctgtat cgttaataac aatgcggcgg cggtgttatt gatgttggcg
     1501 gccactgcca gcgggaaaga ggtggtggtt tctcgcggcg aactggtgga gattggcggc
     1561 gcgtttcgta ttcccgatgt tatgcgtcag gcaggctgca ccctacacga agtagggacc
     1621 accaaccgca cgcacgcgaa tgattatcgt caggcggtga atgaaaatac cgcactgttg
     1681 atgaaagtac ataccagtaa ctacagcatt caggggttca ccaaagcgat agatgaagcg
     1741 gaactggtgg cgctcggcaa agagctggat gttcccgtag tgactgattt aggcagtggc
     1801 tcgctggtcg atcttagcca gtacggtttg ccgaaagagc caatgccgca ggagttgatt
     1861 gcggcgggcg tcagtctggt gagtttctcc ggcgacaagt tgttaggcgg gccgcaggca
     1921 ggaattattg ttggtaaaaa agagatgatc gcccgcctgc aaagccaccc gctgaagcgt
     1981 gcattacgcg cggataaaat gaccctcgcg gcgctggaag ccacgttgcg tctttattta
     2041 caccctgaag ctctgagtga aaaattaccg accctgcgcc tgcttacccg cagcgcagag
     2101 gtcattcaaa tccaggcaca acgtttacag gccccccttg ccgcacatta cggcgcggag
     2161 tttgcggtac aggttatgcc atgtctttcg cagattggca gtggttcgct gccggttgat
     2221 cgcctgccga gcgcggcatt aacgtttaca ccccatgatg gacgcggtag ccaccttgag
     2281 tcattagccg cccgctggcg tgaattgcca gtgccggtga ttggtcgtat ttatgacgga
     2341 cgattgtggc tggatttacg ctgccttgaa gatgagcaac ggtttttgga gatgttgttg
     2401 aaatgattat tgcgactgcc ggacacgttg accacggcaa aacaacctta ttgcaggcga
     2461 ttactggcgt aaatgctgac cgtctgccgg aagaaaaaaa gcgcggcatg accatcgatc
     2521 tcggctatgc ctactggccg cagccggatg gtcgcgtgcc tggttttatc gacgtacccg
     2581 gtcatgaaaa gtttctttcc aacatgctgg cgggcgttgg tggtatcgat cacgcgctgt
     2641 tggtggtggc gtgcgatgac ggcgtgatgg cacagacccg tgagcatctg gcgattttgc
     2701 agctgaccgg taacccgatg ctgacagtgg cgctgaccaa agccgatcgc gtggacgaag
     2761 cgcgtgttaa tgaggttgaa cgccaggtaa aggaggtgct gcgggaatac ggttttgctg
     2821 aggcaaaact gtttatcacc gcagcaaccg aaggtcgggg aattgatgcc ctgcgcgagc
     2881 atctgcttca gttgccggaa cgcgagcacg ccagccaaca tagtttccgc ctcgctattg
     2941 accgcgcatt taccgtaaaa ggtgccgggc tggtcgtcac cggtacggcg ttaagcgggg
     3001 aagtgaaggt aggcgattca ctctggctga ctggtgtaaa taaaccgatg cgtgtacgtg
     3061 cgctgcatgc gcaaaaccag ccaacagaaa ccgccaatgc cgggcagcgt atcgcgctta
     3121 acatcgcggg tgatgcggaa aaagagcaga ttaaccgtgg cgactggctg cttgccgatg
     3181 tgccgccaga gccgttcaca cgggtgattg tcgagcttca aacccataca ccgctgaccc
     3241 agtggcagcc gctgcatatt caccacgccg ccagccacgt cacgggacgc gtttcactgc
     3301 tggaagataa ccttgccgag ctggtgttcg acacgccgct gtggctggcg gataacgatc
     3361 gcttagtgct gcgcgatatc tcggcccgca acacgctggc gggggcgcgt gtggtgatgc
     3421 ttaacccgcc gcgtcgcggt aaacgtaagc cggaatatct gcaatggctg gcgtctcttg
     3481 cacgggcgca gagcgatgcc gatgcgttat ctgttcatct ggaacgcggc gcggttaacc
     3541 ttgcggattt cgcctgggcg cgccagctca acggcgaagg gatgcgcgaa ttgctgcaac
     3601 agcctggcta tattcaggct ggttatagct tgttgaatgc gccggttgcc gctcgctggc
     3661 aacggaaaat tctcgacaca ttagcgactt atcatgagca acatcgcgat gaacctgggc
     3721 ctgggcgcga acgtctgcga cgtatggcgt tgccaatgga agatgaagcg ctagtactgt
     3781 tgctgattga aaagatgcgc gaaagcggcg acatcctcag tcatcacggt tggctgcatc
     3841 tgccggatca caaagcgggc ttcagcgaag agcagcaggc catctggcaa aaagcagagc
     3901 cgctgtttgg tgacgagccg tggtgggtgc gtgatctggc aaaagagacg ggtaccgacg
     3961 agcaggcaat gcgcctgacg ctacgccagg cggcgcagca aggaataatt accgcgatcg
     4021 tcaaagatcg ttattaccgt aacgatcgga ttgtcgaatt tgccaatatg atccgcgatc
     4081 tcgatcagga gtgtggttca acctgcgcgg cggatttccg cgatcgctta ggcgtaggcc
     4141 gaaagctggc aattcagatt ctggaatatt ttgaccgcat tggctttacg cgtcgtcgtg
     4201 gaaatgatca t
//
LOCUS       DAPGUL010000227         4078 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.231, whole genome shotgun sequence.
ACCESSION   DAPGUL010000227 DAPGUL010000000
VERSION     DAPGUL010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4078
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.231"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..1732
                     /locus_tag="RHX21_004681"
     CDS             <1..1732
                     /locus_tag="RHX21_004681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDV1989744.1"
                     /translation="CNVKTEQLQQFIKIMEQKAQLPIYIDKNNLKESIFSVLHNDPQH
                     VDKDQHLPCDKFLKHACKSSNSFEVKLDATHQYQHLNNFMIAFDPVENQLTIRDNNNE
                     TETFSFTNLQWENVLQYYKENQQQPNIAESRNLTDNRDKIKNTISTSEIIECASPEIR
                     SSVLNDLYSIANFLPDNNLPPNESWKRFCHTCERFYVAQKSITGDNSERLTRKVSISD
                     AGITMTFKIGDVVINTISTAIPEDESGQRCIEGLNLAGMDLTGIDLSNMVLRNVNFNG
                     SILRNADFTGTICEGVDFTDCDLRYATFIDASLEKIDFRKVRHLLNINFTNANLRNSN
                     FSGKVLTGVNFTGSDLSNAYLAHIDFTKVIFFPSLIIGAVFDYSNLSEKNLSDKDLTN
                     ISCMYTNFTNANLTKCKLFNTNFSAAKFDNTNFTGTEGSNILFNHAWLFNTIFIDTIF
                     KNACFFNAKVNNVSLKNAYIYNDNIDKKANDSTEKQANDSIEKQANDSTEKQTNDSIE
                     KQASDSIEKQANDSTDKQAKNSTDKQAKNSTEQQDSTSFNEARLKKEVNSNFSIPGLT
                     SYQPTYIVDE"
     gene            1992..2834
                     /locus_tag="RHX21_004682"
     CDS             1992..2834
                     /locus_tag="RHX21_004682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313321.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiK family protein"
                     /protein_id="HDV1989745.1"
                     /translation="MKKRITFIVFLCAIVAVSLFFVQSCVRKSQHVSGFQNYQATIDG
                     KEITGVTKNISSLTWSAQSNTLFSTINKPATIVEMTTEGNLIRTIPLDFVKDLETIEY
                     IGDNKFVISDERDYAIYVISLNADSEVSILKKIKIPLQETPTNCGFEGLAYSSQDHTF
                     WFFKEKNPIEVYKVTGLLRSDELHISKDKALQRQFTLDDVSGAEFNPQKNTLLVLSHE
                     SRALQEVTVTGDVIGEMSLTKGRYGLSHNIKQAEGIAMDASGNIYIVGEPNLFYRFTS
                     TKSR"
     gene            2902..>4078
                     /locus_tag="RHX21_004683"
     CDS             2902..>4078
                     /locus_tag="RHX21_004683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1989746.1"
                     /translation="MNSTSHPGERFSFSTALFGMLVLTLGMGLGRFLYTPMLPVMLAE
                     GEFSFSELSWIASGNYAGYLAGSLLFSFGAFHLPSRLRPFLLASALATGLLILAMAWL
                     PPFLLVFIIRFLAGVASAGMLIFGSTLIMQHTRHPFVLAALFSGVGVGIALGNEYVLA
                     GLHFALSSQTLWQGAGALSAIILLALALLIPSNKHVIAPAPLAKIAQQPMSWWLLAIL
                     YGLAGFGYIIVATYLPLMAKDAGQPVLTAHLWTLVGLSIVPGCFGWLWAAKRWGALPC
                     LTANLLVQAICVLLTLASSSPLLLIISSIGFGGTFMGTTSLVMTIARQLSVPGNLNLL
                     GFVTLIYGIGQILGPALTSMLGNGTSALASATLCGAAALFIAALICGMQIFKLHTNYS
                     "
BASE COUNT         1170 a          913 c          864 g         1131 t
ORIGIN      
        1 ctgcaatgtt aaaacagagc aattgcagca gtttattaaa ataatggaac aaaaagcgca
       61 actaccaatc tatattgaca agaacaattt gaaagagagt attttctctg ttttgcacaa
      121 tgacccacaa cacgtagata aagatcaaca ccttccctgt gataagtttt taaaacatgc
      181 ctgcaaaagt tcaaattcat ttgaagtgaa attagatgcc actcatcaat atcaacacct
      241 gaataatttc atgattgctt ttgacccagt agaaaatcaa ttaaccatac gggataacaa
      301 taacgagact gaaactttct cgttcacaaa cctacaatgg gaaaatgtgc tgcaatacta
      361 caaagaaaac cagcagcagc caaatatagc agaatcacgg aatctcacgg ataatagaga
      421 taaaattaaa aatacaatat ccacctctga aattattgag tgcgcctctc ctgaaataag
      481 aagtagcgtc ctgaacgatc tttatagcat tgctaatttc ctcccggaca ataatctgcc
      541 cccaaatgag agctggaaaa gattttgtca tacatgcgag cgcttttacg ttgctcagaa
      601 gagtatcact ggagataaca gtgaacgtct tacgcgaaaa gtctctatct ctgatgcagg
      661 aattacaatg accttcaaga taggtgatgt tgtcatcaat actattagca ctgctatccc
      721 tgaagatgaa tcgggtcaac ggtgtataga agggttgaat ttagcgggaa tggatttaac
      781 cggcatagac ttgtctaata tggttctaag gaatgtcaat tttaatggca gcattcttag
      841 aaatgcggat ttcaccggta cgatctgtga aggcgtggat tttaccgatt gtgatctccg
      901 ttatgcaacc tttattgacg cctcattaga aaaaatcgat tttcgtaaag ttcgccactt
      961 gcttaatata aattttacaa atgcaaatct acggaacagt aacttcagcg gaaaagttct
     1021 cactggcgtt aattttactg gaagtgacct tagtaacgct tatcttgcac acatagattt
     1081 cacaaaagtg attttctttc cgtcattaat tattggagca gtatttgatt attccaatct
     1141 atcagagaaa aatctttcag acaaagatct tactaatatt agctgcatgt ataccaattt
     1201 tactaacgct aatttaacaa aatgcaaact ctttaataca aacttttcgg ctgcaaaatt
     1261 tgacaatact aatttcactg gtacagaagg ttcgaatatt ctatttaacc atgcatggtt
     1321 gttcaatacg atatttatag atacgatttt taaaaatgcc tgttttttca atgccaaagt
     1381 gaataatgtt tctcttaaga atgcatatat ttacaatgat aatatcgata aaaaagccaa
     1441 tgacagtacc gagaaacaag ccaatgacag tatcgagaaa caagccaatg acagtaccga
     1501 gaaacaaacc aatgacagta tcgagaaaca agccagtgac agtatcgaga aacaagccaa
     1561 tgacagtacc gataaacaag ccaagaacag taccgataaa caagccaaga acagtactga
     1621 gcaacaggac agtaccagtt ttaatgaagc ccgtttaaag aaagaagtga atagcaattt
     1681 ttccattccg ggtttaacgt cttatcagcc aacgtatata gttgacgaat agttcaataa
     1741 tcacccaaac agagtgagta tggcagagga tataaattgc taaccgcctc atctatcatt
     1801 catggatgag gcgcatttat cagtcgatgt aagctgaaaa tgttccgcca tccagagaca
     1861 aacgccgcaa ctcccctgcg gcgtttacta tttcatcgcc cgcgttaaga attcattaag
     1921 cttcatccgt atactcctta tctgtcgcac tgaatttgac gagaaaaaaa gcaataataa
     1981 ggagcaacaa gttgaaaaag cgcatcacct ttatcgtttt tctttgcgcc atcgtggcgg
     2041 tgagcctgtt ttttgtgcaa tcctgcgtcc gtaaaagcca gcatgtctca gggtttcaga
     2101 attatcaggc cactatcgat ggtaaagaga ttacaggagt aactaaaaat atctcctcac
     2161 tgacctggtc tgcgcagagc aataccttgt ttagcactat caacaaacct gcaaccatcg
     2221 ttgaaatgac gaccgagggt aacctgatcc gcaccattcc gctcgatttt gttaaggatc
     2281 tcgagacgat tgaatacatt ggtgataata aatttgtcat cagtgatgaa cgtgattatg
     2341 ccatttatgt gatttcactt aacgctgact cggaagtgag catcctcaaa aaaattaaaa
     2401 tcccattgca ggaaacacca actaactgtg gctttgaagg gctggcttac tcctctcagg
     2461 accatacctt ctggtttttt aaagagaaaa atccgataga ggtctacaaa gtaaccgggc
     2521 tattgcgtag cgatgagttg catatcagca aagataaagc gttgcagcgt cagtttactt
     2581 tggatgatgt ttctggcgcg gaatttaacc cacaaaaaaa tacgttgctg gtgttgtcac
     2641 atgagtcacg cgccctgcag gaagtgaccg tgacaggtga cgtgatcggc gaaatgtcgt
     2701 taaccaaagg caggtatggc ctttcacaca acatcaagca ggcggaaggg atagcgatgg
     2761 atgccagtgg caacatctat atcgttggcg aacccaatct tttttatcgc tttacgtcga
     2821 caaaatcacg ataacagtct ggcaggttct ccttttttgt tattaacttg ttaactcaaa
     2881 ataatacaaa ccaggcagaa catgaattcg acatcgcatc ccggagaacg tttttctttc
     2941 agcaccgcgt tattcgggat gctggttctg accttaggta tgggtttagg ccgctttctc
     3001 tatacgccga tgctgccagt catgctggcg gaaggcgaat tttcctttag cgaactctca
     3061 tggatcgcca gcggtaacta tgccggatat ctggcgggga gcctgctgtt ttcattcggc
     3121 gcgtttcatt taccctcacg cctgcgcccg ttcctgttag cttccgccct cgcaaccgga
     3181 ttattaatcc tcgcgatggc gtggctaccg ccgtttcttc tggttttcat cattcgcttt
     3241 ctggcgggag tcgccagcgc cgggatgttg attttcggct caacgctcat catgcaacat
     3301 acccgccatc cttttgtcct tgcggcgcta ttttctggtg ttggcgtcgg catcgctctg
     3361 ggcaatgaat atgtgctggc aggcctgcat tttgccctct cttcacaaac gttgtggcaa
     3421 ggtgccggag cactttctgc cattatattg cttgctctgg cgctgctcat cccgtcgaat
     3481 aaacacgtta tcgcgccagc gccattggca aaaatcgcgc aacaacccat gagctggtgg
     3541 ttactggcga ttttgtatgg tctggcgggt tttggttata tcatcgtcgc cacctacctg
     3601 ccgctcatgg cgaaagacgc gggccagcct gtgctgacgg ctcacctttg gacactggtt
     3661 ggcttgtcaa ttgtccctgg ttgctttggc tggctgtggg cagccaaacg gtggggagca
     3721 ttaccttgcc tgaccgcgaa tttgctggtg caggcgatct gcgtgctgtt aactctcgcc
     3781 agcagctctc ctttattact catcatcagc agtattggtt ttggcggcac ctttatgggg
     3841 acgacctcgc tggtgatgac catcgcccgc cagcttagcg tgccgggaaa tcttaacctt
     3901 ttgggctttg tgacactgat ttatggtatc gggcaaattc ttggcccggc actgaccagt
     3961 atgctcggca acggaacgtc ggccctcgcc agtgccacgc tctgcggcgc agcggcgcta
     4021 tttatcgcag cattaatctg cgggatgcaa atattcaaat tgcatacgaa ttattctt
//
LOCUS       DAPGUL010000228         4046 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.232, whole genome shotgun sequence.
ACCESSION   DAPGUL010000228 DAPGUL010000000
VERSION     DAPGUL010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4046
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.232"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(188..1378)
                     /locus_tag="RHX21_004684"
     CDS             complement(188..1378)
                     /locus_tag="RHX21_004684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001131474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDV1989747.1"
                     /translation="MPLTARQVETAKPKDKIYKIADGGGLYLQVNPNGSKYWRMKYHY
                     AGKEKKLSFGTYPTITLAEARKRRDEAKKIHADGKDPGEVKKAENLEKNLSEGRTFAA
                     IATEWYNAKVSGWSASYADYVDRAFKNNVFPYIGNRPISEIEPLELLAVLQRIESRGA
                     CELANKVRQRCGEVFRYAIVTGRARYNPASDLVIAMKSYKRTHYPFLLPPELPEFLYK
                     LENYTGSIVTREATKLLMLTGLRTVELRMGEWCEIDFTQKIWEVPPTRMKMRKEHIVP
                     LSDQAIQSLQILKELTGRYRYIFAGRNDVNRPISDASVNMVLKKIGYDKKATGHGFRH
                     TMSTVLHEQGFNSAWIEMQLAHTDKNSIRGTYNHARYLEGRREMMQWYADYLDALRKE
                     SPAI"
     gene            complement(1554..1628)
                     /locus_tag="RHX21_004685"
     tRNA            complement(1554..1628)
                     /locus_tag="RHX21_004685"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1593..1595),aa:Arg,seq:cct)
     gene            complement(1704..2636)
                     /locus_tag="RHX21_004686"
     CDS             complement(1704..2636)
                     /locus_tag="RHX21_004686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDV1989748.1"
                     /translation="MDNDKIDQHSDEIEVESEEKESGKKIEIDEDRLPSRAMAIHEHI
                     RQDGEKELERDAMALLWSAIAAGLSMGASLLAKGIFHVELEGVPGSFLLENLGYTFGF
                     IIVIMARQQLFTENTVTAVLPVMQKPTMSNVGLLMRLWGVVLLGNILGTGIAAWAFEY
                     MPIFNEETRDAFVKIGMDVMKNTPSEMFANAIISGWLIATMVWMFPAAGAAKIVVIIL
                     MTWLIALGDTTHIVVGSVEILYLVFNGTLHWSDFIWPFALPTLAGNICGGTFIFALMS
                     HAQIRNDMSNKRKAEARQKAERAENIKKNDKNPA"
     gene            2930..3685
                     /gene="mlaA"
                     /locus_tag="RHX21_004687"
     CDS             2930..3685
                     /gene="mlaA"
                     /locus_tag="RHX21_004687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid-binding lipoprotein MlaA"
                     /protein_id="HDV1989749.1"
                     /translation="MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNF
                     NVLDPYIVRPVAVAWRDYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTR
                     FFLNTILGMGGFIDVAGMANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRD
                     DGGDMADGLYPVLSWLTWPMSVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYF
                     QRHDFIANGGELKPQENPNAQAIQDDLKDIDSE"
     gene            complement(3866..4046)
                     /locus_tag="RHX21_004688"
                     /pseudo
     CDS             complement(3866..4046)
                     /locus_tag="RHX21_004688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416847.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1010 a          917 c          927 g         1192 t
ORIGIN      
        1 agtaatttct tagtatttca tcataagcgt ttatctatcg tctctttcta aattaaccgg
       61 tcgtattaca aggtgctgaa tctgattaag gaatgatact taggggatta tggctgactt
      121 aataattaga taactgataa atgactatca gggggatatc gttaagtcag cctttaaaat
      181 caagcgatta tatagctggt gactcttttc gaagagcatc aaggtagtca gcgtaccatt
      241 gcatcatttc tcgtcttcct tcaaggtaac gagcatggtt gtatgtacca cgaatgctgt
      301 ttttgtccgt atgtgcaagt tgcatttcaa tccatgcact attgaatcct tgctcgtgta
      361 gaacagtact cattgtatga cgaaatccat gcccggtagc ttttttgtca tagccaatct
      421 tcttcaaaac catattgacg cttgcatcgc tgataggcct gttaacatca tttcttccgg
      481 caaagatgta tctgtatctt ccagtcagtt ctttgaggat ttgcagagac tggattgcct
      541 gatctgacag agggacgata tgctccttcc tcattttcat ccgggtcgga ggaacttccc
      601 atatcttttg ggtaaaatcg atctcacacc attcccccat acgtaattct actgttctca
      661 gccctgtgag catcaacaat tttgtagctt cacgggttac aatactgccg gtgtagtttt
      721 cgagtttgta taaaaactct ggtagttcag gaggaagcag gaaagggtaa tgtgttcgct
      781 tatagctttt cattgctata accagatcag aagctggatt gtatcgtgcc cgacctgtaa
      841 caatggcata ccgaaacact tcaccacatc gttggcgaac tttattagct agctcgcagg
      901 ctcctcggct ttcgatacgc tgaagaactg cgagaagttc aagaggttcg atttcactaa
      961 tgggtctgtt tccaatgtag ggaaacacat tatttttgaa tgctctgtcg acataatcag
     1021 cgtagctggc agaccagcct gaaacttttg cgttgtacca ctcggtggcg attgcggcaa
     1081 aagttcttcc ttcggaaagg tttttctcaa gattttcagc tttcttgact tcaccgggat
     1141 ctttaccatc ggcatgtatt ttcttggctt catcccgacg tttgcgagct tcagccaatg
     1201 taatagttgg ataggtgcca aatgatagtt tcttttcctt ccccgcatag tggtacttca
     1261 ttcgccagta ctttgagccg ttaggattga cctgaaggta gagcccacca ccatcggcaa
     1321 tcttataaat tttatctttg ggtttggctg tttcaacttg tcgagctgtc agtggcatct
     1381 gggggcctcg caatagattg accaagatgt gcccctaaat aggcccccaa atgtgacttg
     1441 atttacgttc ccctgaggag aattaaggcg actatttgag taacataagt aagggtatgt
     1501 gctgattata aaggcttttt gtggggtatg gtagatttca ggagaggtgt gcatggtgtc
     1561 ccctgcagga atcgaacctg caattagccc ttaggagggg ctcgttatat ccatttaact
     1621 aagaggacaa tgcggcatga gtatacccgc taatggactg cggggtaagt acgctgccgc
     1681 tcgattgctt aaaccctcgc catttatgcc gggtttttat catttttctt aatgttttcc
     1741 gcacgttctg ctttttggcg tgcttctgct ttgcgcttgt tgctcatgtc gttacggatc
     1801 tgtgcatgac tcattaacgc gaagataaag gtgccgccgc agatgttccc cgctaaagta
     1861 ggtagtgcga agggccagat gaaatcgctc cagtgcagcg taccgttaaa caccagatag
     1921 aggatttcta cagaaccgac aacgatgtga gtggtgtcac ccagggcaat aagccaggtc
     1981 atcaatataa tcaccacaat ctttgccgca cccgctgcag gaaacatcca taccatagtg
     2041 gcgatcagcc agccggaaat gatcgcgttg gcaaacatct cgctgggggt gttcttcatc
     2101 acatccatgc cgattttgac aaatgcatcg cgagtttctt cattgaagat tggcatatat
     2161 tcaaatgccc acgccgcaat acctgtcccg agaatattac ccagcagcac gacgccccat
     2221 aaccgcataa gtaagccaac gttgctcatt gtcggttttt gcatgacggg tagtaccgca
     2281 gtcacggtgt tttcggtaaa taattgctgg cgggccataa tgacgataat aaaaccaaag
     2341 gtataaccga gattctccag caagaagctg cccggcacac cttccagttc gacatgaaat
     2401 atcccttttg ccagtaatga agcgcccatc gacagacccg ccgcaatggc tgaccacagt
     2461 agtgccattg cgtcgcgttc cagctctttt tcaccatcct ggcggatatg ctcatgaatt
     2521 gccatcgccc gggaggggag tcgatcttca tctatttcta tttttttgcc actctctttt
     2581 tcttcgctct caacttcaat ttcgtcgctg tgttgatcaa ttttgtcgtt gtccatggtc
     2641 tcttctcttg aattagcacg tatagctaaa gcgtagcggc tttttcgctc gcaactggcg
     2701 ggagttactc tgaaaatgta gaaaaggccg cgtttgcctt tttctgtttc tatagaatca
     2761 agtagcctac agggcggcga ttaccaggct atgatcaaat cagcaaatca gggcgtctgg
     2821 acatcagttg acgtgctgtt acaatcgccc acacctaaac aggcggatac ggtatcgttc
     2881 cgtcatggat ggcaaactgc ataagccata aaaaaacagg gagacattta tgaagcttcg
     2941 cctgtcggcg cttgctctgg gaactacgct tctggtgggg tgtgcgagtt ccggtacaga
     3001 tcagcaaggg cgttctgacc cgttagaagg gttcaaccgc accatgtaca acttcaactt
     3061 caatgtatta gacccgtata ttgttcgacc ggtcgctgtt gcctggcgtg attatgttcc
     3121 acaaccggcg cgtaacggtt tgagcaactt taccggcaac cttgaagaac ccgcggtgat
     3181 ggtgaactac ttcttgcagg gcgaccctta tcaggggatg gtccacttta cccgcttttt
     3241 cctgaacacc attttgggga tgggtggttt tattgatgtt gcagggatgg cgaacccgaa
     3301 actgcaacgg actgaacctc accgcttcgg tagtacgctt ggtcattatg gcgtgggtta
     3361 tgggccttac gtccagttac cgttctacgg tagcttcacg ctgcgtgatg acggtggtga
     3421 tatggcggat ggtctttacc cggttctatc ctggctgacc tggccgatgt ctgtgggtaa
     3481 atggacgctt gaagggatag aaactcgtgc gcagttgttg gattccgacg gtctgctgcg
     3541 tcagtcgtcc gatccttata ttatggtgcg cgaagcgtac ttccagcgtc atgatttcat
     3601 cgctaatggc ggcgaactca aaccgcagga aaatccgaac gcgcaagcga ttcaggatga
     3661 tttaaaagat atcgattctg aataagaaac aaataaaaaa ggtgagtcgc aatactcacc
     3721 ttttttgttg ttatccctca attaccacaa gtaaaaggag ataaaccgac aatgacccgg
     3781 acgtaattat gtaaaaatac tgatgttcgt cactgactat ttccgatatt cagctgttga
     3841 aaaatcaaaa aactggaaaa ataatttaaa tatcatcaaa attaacacct agcgcatata
     3901 gttgattaat ttcattttga tatttcgtct ggcgatcttg aagccttttt caatgttacc
     3961 ttcgagttcc ttaaagtgct tatatatttt ttgagaatgg tcaacgttaa cttcgttacc
     4021 gaataaagta gaaactattt cttttg
//
LOCUS       DAPGUL010000229         4039 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.233, whole genome shotgun sequence.
ACCESSION   DAPGUL010000229 DAPGUL010000000
VERSION     DAPGUL010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4039
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.233"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..252)
                     /locus_tag="RHX21_004689"
     CDS             complement(<1..252)
                     /locus_tag="RHX21_004689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HDV1989750.1"
                     /translation="MEIRIMLFILMMMVMPVSYAACYSELSVQHNLVVQGDFALTQTQ
                     IATYEHNFNDSSCVSTNTITPMSSSDIIVGLYNDTIKLNL"
     gene            complement(268..2748)
                     /locus_tag="RHX21_004690"
     CDS             complement(268..2748)
                     /locus_tag="RHX21_004690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDV1989751.1"
                     /translation="MLRMTPLASAIVALLLGIEAYAAEETFDTHFMIGGMKDQQVANI
                     RLDDNQPLPGQYDIDIYVNKQWRGKYEIIVKDNPQETCLSREVIKRLGINSDNFASGK
                     QCLTFEQLVQGGSYTWDIGVFRLDFSVPQAWVEELESGYVPPENWERGINAFYTSYYV
                     SQYYSDYKASGNSKSTYVRFNSGLNLLGWQLHSDASFSKTNNNPGVWKSNTLYLERGF
                     AQLLGTLRVGDMYTSSDIFDSVRFRGVRLFRDMQMLPNSKQNFTPRVQGIAQSNALVT
                     IEQNGFVVYQKEVPPGPFAITDLQLAGGGADLDVSVKEADGSVTTYLVPYAAVPNMLQ
                     PGVSKYDFAAGRSHIEGASKHSDFVQAGYQYGFNNLLTLYGGSMVANNYYAFTLGTGW
                     NTRIGAISVDATKSHSKQDNGDVFDGQSYQIAYNKFVSQTSTRFGLAAWRYSSRDYRT
                     FNDHVWANNKDNYRRDENDVYDIADYYQNDFGRKNSFSANMSQSLPEGWGSVSLSTLW
                     RDYWGRSGSSKDYQLSYSNNLRRISYTLAASQAYDENHHEEKRFNIFISIPFDWGDDV
                     STPRRQIYMSNSTTFDDQGFASNNTGLSGTVGSRDQFNYGVNLSHQHQGNETTAGANL
                     TWNAPVATVNGSYSQSSTYRQAGASVSGGIVAWSGGVNLANRLSETFAVMNAPGIKDA
                     YVNGQKYRTTNRNGVVVYDGMTPYRENHLMLDVSQSDSEAELRGNRKIAAPYRGAVVL
                     VNFDTDQRKPWFIKALRADGQPLTFGYEVNDIHGHNIGVVGQGSQLFIRTNEIPPSVN
                     VAIDKQQGLSCTITFGKEIDESRNYICQ"
     gene            complement(2764..3438)
                     /locus_tag="RHX21_004691"
     CDS             complement(2764..3438)
                     /locus_tag="RHX21_004691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HDV1989752.1"
                     /translation="MKGLLSLLIFSMVLPAHAGIVIYGTRIIYPAENKEVMVQLMNQG
                     NRSSLLQAWIDDGDTSLPPEKIQVPFMLTPPVAKIGANSGQQVKIKIMPNKLPTNKES
                     IFYLNVLDIPPNSPEQEGKNALKFAMQNRIKLFYRPAGIAPVNKATFKKLLVNRSGNG
                     LVIKNDSANWVTISDVKANNVKVNYETIMIAPLESQSVNVKSNNANNWYLTIIDDHGN
                     YISDKI"
     gene            complement(3518..>4039)
                     /locus_tag="RHX21_004692"
     CDS             complement(3518..>4039)
                     /locus_tag="RHX21_004692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HDV1989753.1"
                     /translation="AAVFSSFFMSAGVFAADVDTGTLTIKGNIAESPCKFEAGGDSVS
                     INMPTVPTTVFEGKAKYSTYDDAVGVTSSMLKISCPKEVAGVKLSLITNDKITGNDKA
                     IASSNDTVGYYLYLGDNSDVLDVSAPFNIESYKTAEGQYAIPFKAKYLKLTDNSVQSG
                     DVLSSLVMRVAQD"
BASE COUNT         1135 a          985 c          747 g         1172 t
ORIGIN      
        1 taaatttaat tttatggtat cgttataaag cccaacaata atatccgacg aactcatagg
       61 ggtgatagta tttgtactca cgcatgacga atcattaaaa ttatgctcat atgtcgctat
      121 ttgtgtttga gtaagtgcaa aatccccctg aacaaccaaa ttgtgctgaa cagataactc
      181 actataacat gccgcatagc tcacaggcat aaccatcatc attaatataa atagcattat
      241 gcgaatttcc atagaaccac ctgactatta ctggcaaata taatttctac tttcatcaat
      301 ctctttaccg aaggtgattg tgcatgaaag tccttgttgc ttatcaattg ctacattaac
      361 cgatggcggt atttcattgg tgcgaataaa taactggctt ccctggccga caacgccaat
      421 attatgaccg tggatatcat tgacttcata accaaacgtt aatggttgcc catccgctct
      481 taacgctttt ataaaccagg gcttgcgctg atcggtatca aaattaacca gtacaaccgc
      541 gccgcgataa ggtgcggcaa ttttccggtt gccacgtaat tctgcttcgc tatcgctttg
      601 cgacacatcc agcatcaggt gattttcccg ataaggtgtc attccgtcgt ataccaccac
      661 tccattacgg tttgttgtgc gatatttttg cccattgaca taagcatctt taattcctgg
      721 cgcattcatc acagcaaacg tttcggaaag acggttcgcc agattaacgc cacccgacca
      781 ggcgacaatg ccccctgaaa cactggctcc agcctgtcga taagtactcg actgactata
      841 actgccattc actgttgcca ccggcgcgtt ccaggttaaa ttcgctccag ctgtcgtttc
      901 atttccctga tgttgatgac tcaggttgac accataattg aactgatccc gactccctac
      961 tgttcctgat aatcccgtat tatttgaggc aaacccctga tcatcaaacg tcgttgagtt
     1021 agacatatat atttgccgac gaggcgtcga aacgtcatca ccccaatcaa agggaatcga
     1081 tataaaaata ttaaaacgtt tctcttcatg atgattctcg tcataagcct ggcttgccgc
     1141 gagggtatag cttatccgtc gcaggttgtt ggaataactc aactgataat ccttactact
     1201 gccgctacgc ccccagtaat ctcgccataa cgtacttaat gacacagacc cccaaccttc
     1261 tggcaatgac tggctcatat tggcggaaaa gctatttttg cgaccaaaat cattctggta
     1321 ataatcggca atgtcataga catcgttttc atcacggcga taattatctt tattgtttgc
     1381 ccaaacgtga tcgttaaatg tccggtaatc acgcgacgaa taacgccagg ccgccagacc
     1441 aaaacgcgtc gacgtttggc tcacaaattt gttgtaggca atttgataac tttgcccgtc
     1501 aaacacatcg ccgttgtctt gtttactatg cgacttcgtg gcatcgacgg aaatggcacc
     1561 aatgcgtgta ttccagccag tccccaaagt gaacgcgtaa taattattcg caaccatcga
     1621 gccaccatac aacgtcaata agttattaaa accatactga taacccgcct ggacaaaatc
     1681 actatgtttg ctcgcccctt caatatggct acgacccgcc gcaaaatcat atttcgacac
     1741 gccgggttgc agcatatttg gcaccgctgc ataaggcacc agataggtgg ttaccgaacc
     1801 gtccgcctct ttcacgctga catcaagatc tgctccacca ccggccaact gcaaatctgt
     1861 aatcgcaaac gggccaggag gaacctcttt ctgataaacc acaaaaccat tctgttcaat
     1921 agttaccagc gcgttactct gagcaatccc ctgcacccgt ggcgtaaaat tttgtttcga
     1981 gttaggcaac atctgcatat cacgaaacaa ccgcacacct ctgaagcgaa cagaatcaaa
     2041 aatatcgctt gatgtgtaca tatcacccac gcgaagcgtg ccgagaagtt gggcaaatcc
     2101 acgttccaga tacagggtat tgcttttcca cacccctgga ttgttatttg ttttactgaa
     2161 actggcatca gaatgcagtt gccaccccag taaatttaac ccgctgttaa aacgtacata
     2221 tgtactctta ctattacccg acgctttata gtcactgtaa tactgactca cataataaga
     2281 ggtataaaac gcattaatac cccgctccca gttttccggt ggaacatagc cactttccag
     2341 ttcttccacc caggcctgcg ggacactgaa atcgagacga aaaaccccga tatcccaggt
     2401 atagctccca ccctgaacaa gttgctcaaa tgttaaacat tgcttaccgc tggcgaagtt
     2461 atcgctatta atgcctaacc gcttgataac ttctcttgat aaacatgttt cttgcgggtt
     2521 gtctttaaca ataatctcat atttcccgcg ccattgctta ttgacataaa tatcaatgtc
     2581 atactgcccc ggtaagggtt gattatcatc aagacgaata tttgcaacct gctggtcttt
     2641 cattccacct atcataaaat gggtatcaaa ggtttcttca gctgcataag cttcaatgcc
     2701 gagcaataac gctacgattg ctgatgcaag tggggtcatt ctcaacatag gcagctcctg
     2761 caattaaatt ttgtcactaa tatagttgcc gtggtcatcg ataatggtca gataccagtt
     2821 atttgcatta ttacttttga cattaacact ctgactttct aagggggcaa tcattatagt
     2881 ttcataattg actttgacat tattagcttt gacatccgaa atcgtcaccc aattagctga
     2941 gtcatttttt atcaccaatc cattgccact gcgatttacc agtaactttt taaaggtcgc
     3001 tttatttacc ggagcaatac ccgccggccg gtaaaacaat ttgattctgt tttgcatcgc
     3061 aaacttcagt gcattcttac cttcttgttc tggactattt ggtggaatat ccagaacatt
     3121 cagataaaaa atgctttctt tattagtggg cagtttattc ggcataattt tgatttttac
     3181 ttgctgcccg gaatttgccc ctatttttgc aactggtggc gttaacatga aaggaacctg
     3241 aattttttct ggtggtaacg acgtatcgcc atcatcaatc cacgcctgca gcagcgaaga
     3301 acgatttccc tggttcatca actgcaccat aacttcttta ttttctgccg ggtaaataat
     3361 gcgcgtcccg tagataacaa ttccggcatg tgcaggaagg accatagaaa aaatgagtaa
     3421 agataataat cctttcattt taatgcctct taaattaaaa ggccgccatg ggatagcggc
     3481 catgtttatt acctggagaa acttgcaatt ttatttatta atcctgcgcc acacgcataa
     3541 ccagagaaga taacacatca cctgattgca ctgagttatc tgttagtttc aggtattttg
     3601 ctttaaacgg aatagcatat tgaccttccg ctgttttata actctcaata ttaaaaggtg
     3661 cagaaacatc caggacatcg ctgttatcac ctaaatagag atagtaaccc acggtatcgt
     3721 tgctactggc tatcgcctta tcgttgccgg ttattttgtc gttggtaatc aacgagagtt
     3781 ttacaccagc aacttctttc gggcagctaa tttttaacat gctgctggtt acaccgactg
     3841 catcatcata ggtagaatat ttagctttac cttcaaagac agtggttggt acagtcggca
     3901 tattaatact tactgaatca ccacccgctt cgaatttaca cggagattct gcaatatttc
     3961 ctttaatggt taatgttccg gtatcaacgt ctgcagcaaa tactccagcg ctcataaaaa
     4021 aagaagaaaa gacagcggc
//
LOCUS       DAPGUL010000230         3978 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.234, whole genome shotgun sequence.
ACCESSION   DAPGUL010000230 DAPGUL010000000
VERSION     DAPGUL010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3978)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3978)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3978
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.234"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..246)
                     /locus_tag="RHX21_004693"
     CDS             complement(<1..246)
                     /locus_tag="RHX21_004693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDV1989754.1"
                     /translation="MENKNHQQENFKSTYQSLVNSARILFVEKGYQAVSIDEISGKAL
                     VTKGAFYHHFKNKKQLLSACYKQQLIMIDAYITTKTDL"
     gene            334..696
                     /locus_tag="RHX21_004694"
     CDS             334..696
                     /locus_tag="RHX21_004694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDV1989755.1"
                     /translation="MYIEQHSRYQNKANNIQLRYDDKQFHTTVIKDVLLWIEHNLDQS
                     LLLDDVANKAGYTKWYFQRLFKKVTGVTLASYIRARRLTKAAVELRLTKKTILEIALK
                     YQFDSQQSFTRRVMTPTY"
     gene            complement(690..962)
                     /locus_tag="RHX21_004695"
                     /pseudo
     CDS             complement(690..962)
                     /locus_tag="RHX21_004695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
     gene            1086..2489
                     /locus_tag="RHX21_004696"
     CDS             1086..2489
                     /locus_tag="RHX21_004696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001157239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HDV1989756.1"
                     /translation="MLEKAEAEEQLRQENDKKLLGQVLEIYDQKYVAELLRKVGKNEW
                     SRETLNRWINGKCSPKTLTSAEEELLRKMLPEAPAHHPNYAFRFIDLFAGIGGIRKGF
                     ETIGGQCVFTSEWNKEAVRTYKANWFNDAQEHTFNLDIREVTLSDKPEVPENDAYAYI
                     NEHVPDHDVLLAGFPCQPFSLAGVSKKNSLGRAHGFECEAQGTLFFDVARIIRAKKPA
                     IFVLENVKNLKSHDKGKTFKVIMDTLDELGYEVADAAEMGKNDPKVIDGKHFLPQHRE
                     RIVLVGFRRDLNIHQGFTLRDISRFYPEQRPSFGELLEPVVDSKYILTPKLWEYLYNY
                     AKKHAAKGNGFGFGLVNPENKESIARTLSARYHKDGSEILIDRGWDMATGETDFANEE
                     NQAHRPRRLTPRECARLMGFEKVDGRPFRIPVSDTQSYRQFGNSVVVPVFEAVAKLLE
                     PYILKAVNADSCKVERI"
     gene            complement(2523..3737)
                     /locus_tag="RHX21_004697"
     CDS             complement(2523..3737)
                     /locus_tag="RHX21_004697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_143212653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II site-specific deoxyribonuclease"
                     /protein_id="HDV1989757.1"
                     /translation="MFMSVFHNWLLEIACENYFVYIKRLSANDTGATGGHQVGLYIPS
                     GIVEKLFPSINHTRELNPSVFLTAHVSSHDCPDSEARAIYYNSRHFGKTRNEKRITRW
                     GRGSPLQNPENTGALTLLAFKLDEQGGDCKEVNIWVCASTDEEDVIETAIGEVIPGAL
                     ISGPAGQILGGLSLQQAPVNHKYILPEDWHLRFPSGSEIIQYAASHYVKNSLDPDEQL
                     LDRRRVEYDIFLLVEELHVLDIIRKGFGSVDEFIALANSVSNRRKSRAGKSLELHLEH
                     LFIEHGLRHFSTQAITEGNKKPDFLFPSAGAYHDTEFPVENLRMLAVKTTCKDRWRQI
                     LNEADKIHQVHLFTLQEGVSLAQYREMRESGVRLVVPSSLHKKYPEAVRAELMTLGAF
                     IAELTELYADIP"
BASE COUNT         1108 a          894 c          910 g         1066 t
ORIGIN      
        1 taaatcagtt tttgttgtga tgtaggcatc aatcataatt aattgctgct tataacaggc
       61 actgagtaat tgttttttat ttttaaagtg atgataaaag gcacctttgg tcaccaacgc
      121 ttttcccgag atctcatcta ttgaaacagc ttgatagcct ttttcaacaa acaatattcg
      181 tgctgagtta accagtgatt gataggtact cttaaaattt tcttgttgat gatttttatt
      241 ttccatgata gatttaaaat aacataccgt cagtatgttt atggtatcat gatgatgtgg
      301 tcgtgacaat cttaagaaca tttaggttat tttatgtata ttgaacagca ttctcgctat
      361 caaaataaag ctaataacat ccaattaaga tatgatgata agcagtttca tacaacggtt
      421 atcaaagatg ttctattatg gattgaacat aatttagatc agtctttact gcttgatgat
      481 gtggcgaata aagcgggtta taccaagtgg tattttcagc ggctgttcaa aaaagtaaca
      541 ggggtcacac tggctagcta tattcgtgct cgtcgtttga cgaaagcggc tgttgagttg
      601 aggttgacga aaaaaactat ccttgagatc gcattaaaat atcaatttga ttcccaacaa
      661 tcttttacac gtcgggtaat gactccaact tactgatagt gttttatgtt caaataatgc
      721 ccgatgacct tgtcatgcaa ctccaccgat tttgagaacg acagtgactt ccgtcccagc
      781 cttgccagat gttgtctcag attcaggtta tgtcgctcaa tgcgctgagt gtaacgcttg
      841 ctgataacgt gcagctttcc cttcaggcgg gattcataca gcggccagcc atccgtcatc
      901 cataccacga cctcaaaggc cgacagcagg cccagaagac gctccagcgt ggccaacgtg
      961 cgttacctaa aacctgttta aatatccaga taaaaacatt caatctgggt caaatgagtg
     1021 atacagtttc acccataaga cccaatggag gcaatatgtc tgaatttgaa ttactggcgc
     1081 aggatctgct tgagaaagca gaagcggaag aacaactgcg acaggaaaat gataaaaagc
     1141 tgctcgggca ggtgctggaa atctatgacc agaagtacgt ggctgaactg cttagaaaag
     1201 ttggtaaaaa tgagtggagt cgcgagactc ttaatcgctg gattaatggt aagtgctcac
     1261 ctaagacgct gacgtcagcc gaagaggaac ttctacgaaa aatgcttccg gaagcgcctg
     1321 cacatcaccc taactatgcc ttccggttta ttgacctgtt tgctgggatt ggaggtatac
     1381 ggaagggctt cgaaaccatc ggtggccagt gcgtttttac cagtgaatgg aataaagagg
     1441 ctgtgcgcac atataaagct aactggttta acgatgctca ggaacacact ttcaatctcg
     1501 atattcggga agtcacgctc agtgataaac ctgaagtacc tgaaaacgat gcctatgctt
     1561 acattaatga gcatgtgccg gatcatgatg tacttctagc aggtttcccc tgtcaaccgt
     1621 tcagccttgc gggcgtaagc aagaaaaact cgctcgggcg cgcgcatggt ttcgaatgtg
     1681 aggctcaggg aacacttttc ttcgatgtgg cgcgtattat ccgcgcaaaa aaacctgcca
     1741 tctttgttct tgaaaacgtt aaaaacctga agagccatga caagggtaaa acctttaaag
     1801 tcatcatgga taccctcgac gaactgggct atgaagttgc ggatgcagct gagatgggca
     1861 aaaacgatcc taaagttatc gacggaaagc actttttacc tcagcaccga gaacgtatcg
     1921 ttttggtcgg tttccgtcgt gatctgaaca ttcaccaggg ctttaccctg cgcgatatta
     1981 gtcgttttta tccggaacag cgtccgtcat ttggcgaact gctggaaccc gtggttgaca
     2041 gcaaatatat actgacgccg aaactctggg agtatctcta taactacgcc aaaaagcacg
     2101 cagctaaggg taacggattc ggttttggcc tcgttaatcc tgaaaataaa gaaagcattg
     2161 cccgtacgct ttctgctcgc tatcacaaag acgggtctga aattctgata gaccgtggct
     2221 gggatatggc cacaggtgaa acagacttcg cgaacgaaga aaatcaggcg catcggcccc
     2281 gtaggctgac tccacgagag tgcgcgcgcc ttatgggttt tgaaaaagta gatggcaggc
     2341 cttttcgcat tcctgtgtca gacactcagt cgtacaggca gttcggtaac tccgtagtgg
     2401 tgcccgtgtt tgaagccgta gccaaactgc ttgaacctta tatcctgaaa gcggttaatg
     2461 ccgattcgtg caaggttgaa cgaatctgat cgctcctccc ggtatttatg ccgggagata
     2521 atctatggaa tatctgcgta aagctctgtc agctcagcaa taaacgcacc tagcgtcatt
     2581 agctcagctc tcaccgcctc cgggtatttt ttgtgcagag atgatggcac gaccaatctg
     2641 acacccgact cccgcatctc ccgatattga gccagagaaa ctccctcctg gagtgtaaac
     2701 agatgcacct gatgaatttt atcggcctca ttcagtatct gacgccagcg atccttacag
     2761 gtagtcttga ctgccagcat gcgcagattt tctacgggaa actcagtatc gtggtaagcc
     2821 cctgcggaag ggaaaaggaa atcgggtttt ttattacctt ctgtgatggc ctgcgtcgaa
     2881 aagtgtcgca ggccgtgctc aatgaataga tgctccaggt gcagttccag cgacttcccg
     2941 gctctggatt tacggcgatt gctgacagaa ttggccagcg caataaattc atccacagag
     3001 ccaaatcctt tccggatgat atccagaaca tgcagttcct caaccaatag aaatatgtcg
     3061 tactccacgc gccggcggtc aagaagttgc tcatccggat caagggaatt tttcacataa
     3121 tggctggctg catactgaat aatttcactt cccgacggaa agcgcaggtg ccagtcttca
     3181 ggtagaatat atttatgatt tactggcgct tgctgtagag atagtccgcc tagaatctgt
     3241 cctgcggggc cggatataag cgctccgggt ataacttcac caatagcggt ctcaatgacg
     3301 tcctcttcat cagtgctggc gcatacccaa atatttactt ccttacagtc ccccccttgc
     3361 tcatcaagct tgaaagctag gagcgtcaga gcacctgtat tttcaggatt ctgaagtggg
     3421 ctgcctctac cccagcgggt aatccttttt tcattccggg ttttaccaaa atgacggctg
     3481 ttataataaa ttgcccgggc ttcgctgtca gggcaatcat gcgatgacac atgtgcggtg
     3541 agaaaaaccg aagggttcag ttcacgggta tggttgatag acggaaagag tttttcaacg
     3601 atacctgaag ggatataaag tcctacctgg tgaccacctg ttgcgccggt atcgttggcg
     3661 gaaaggcgtt tgatgtagac gaagtaattc tcacatgcga tctcgagtag ccagttgtgg
     3721 aaaaccgaca taaacatccc ctgttaccct gaaactctac tcaccatttt ttcataatta
     3781 tatacaaaca gccagaaagg ctgttacagg cgatttgatc tgcaacctat tggttaaatt
     3841 aatgtatcaa aaacgatggt ttctgtgaca catccctata agcagttgcc tatacaataa
     3901 aacgctctcc ggctgtaaca aaacccgtta cagtatcaat acaacaaaaa cgatgtaaca
     3961 aaatagggtg gcaaaatg
//
LOCUS       DAPGUL010000231         3855 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.235, whole genome shotgun sequence.
ACCESSION   DAPGUL010000231 DAPGUL010000000
VERSION     DAPGUL010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3855
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.235"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..531
                     /locus_tag="RHX21_004698"
     CDS             <1..531
                     /locus_tag="RHX21_004698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like protein"
                     /protein_id="HDV1989758.1"
                     /translation="LLVAGVAMILSNNVFADEGHGIVKFKGEVISAPCSIKPGDEDLT
                     VNLGEVADTVLKSDQKSLAEPFTIHLQDCMLSQGGTTYSKAKVTFTTANTMTGQTDLL
                     KNTKETEIGGATGVGVRILDSQSGEVTLGTPVVITFNNTNSYQELNFKARMESPSKDA
                     TPGNVYAQADYKIAYE"
     gene            591..3095
                     /locus_tag="RHX21_004699"
     CDS             591..3095
                     /locus_tag="RHX21_004699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001480735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HDV1989759.1"
                     /translation="MYKKLKLTTISELIKNIYCSLSVLIIGCASAYAVEFNKDLIEAE
                     DRENVNLSQFETDGQLPVGKYSLNALINNKRTPIHLDLQWVLIDNQTAVCLTPEQLTL
                     LGFTDEIIEVAQQNLIDGCYPIEKEKQITTYLDKGKMQLSISAPQAWLKYKDANWTPP
                     ELWDHGIAGAFLDYNLYASHYAPHQGDNSQNISSYGQAGVNLGAWRLRTDYQYDQSFN
                     NGKSQANNLDFPRIYLFRPIPAINAKLTIGQYDTESSIFDSFHFSGVSLKSDENMLPP
                     DLRGYAPQITGVAQTNAKVTVSQNNRIIYQENVPPGPFAITNLFNTLQGQLDVKVEEE
                     DGQVTQWQVASNSIPYLTRKGQIRYTTAMGKPTSVGGDSLQQPFFWTGEFSWGWLNNV
                     SLYGGSVLTNRDYQSLAAGVGFNLNSLGSLSFDVTRSDAQLHNQDKETGYSYRANYSK
                     RFESTGSQLTFAGYRFSDKNFVTMNEYINDTNHYTNYQNEKESYIVTFNQYLESLRLN
                     TYVSLARNTYWDASSNVNYSLSLSRDFDIGPLKNVSTSLTFSRINWEEDNQDQLYLNI
                     SIPWGTSRTLSYGMQRNQDNKISHTASWYDSSDRNNSWSVSASGDNDEFKDMKASLRA
                     SYQHNTENGRLYLSGTSQRDSYYSLNASWNGSFTATRHGAAFHDYSGSADSRFMIDAD
                     GAEDIPLNNKRAVTNRYGIGVIPSVSSYITTSLSVDTRNLPENVDIENSVITTTLTEG
                     AIGYAKLDTRKGYQIMGVIRLADGSHPPLGISVKDKTSHKELGLVADGGFVYLNGIQD
                     DSKLTLRWGDKSCFIQPPNSSNLTTGTVILPCISQN"
     gene            3111..>3855
                     /locus_tag="RHX21_004700"
     CDS             3111..>3855
                     /locus_tag="RHX21_004700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417519.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HDV1989760.1"
                     /translation="MRYLNTKNLIAAGVLLACMSSIAWGAIIPDRTRIIMNESDKGEA
                     LKLTNQSKNLPYLAQTWIEDTKGNKSRDFIVTVPPMVRLNPSEQIQIRMISQEKIAQL
                     PNDRETLFYFNVREIPPKTDKKNVMQVTMQHALKLFWRPKAIELEDDGVMSYEKVEII
                     RRNDGSIRFNNKMPYHVTLGYIGTNGITMLPQTQSLMVTPYSHADTQFKNVPSAFQVG
                     YINDFGGLSFYEINCPTVNNSCNVSVAKRD"
BASE COUNT         1199 a          813 c          791 g         1052 t
ORIGIN      
        1 cttcttgttg ctggcgtagc aatgattctt tccaataacg tatttgctga cgaaggtcac
       61 ggcattgtta aatttaaagg tgaagttatc tctgctccat gttcaattaa accaggtgac
      121 gaagacttaa ctgtaaatct gggtgaagta gcagataccg ttctgaaaag cgaccagaaa
      181 tctttggctg agcctttcac tattcacctg caagactgca tgttgagcca gggtggaacc
      241 acttattcaa aagcgaaggt tactttcacc acagcgaata ctatgacggg tcagactgac
      301 ctgctgaaaa acaccaaaga aactgaaatc ggtggtgcca caggcgttgg cgtacgtatt
      361 ctggatagcc agagcggcga agtgacttta ggtactccgg tagtaattac attcaacaat
      421 actaacagct atcaggaact gaacttcaaa gctcgtatgg aatccccaag caaagatgct
      481 accccgggca acgtttacgc tcaggctgac tataagattg cttacgagta atcacattag
      541 gccgggttcg cccggccaca tcattaacgg attaatgata agtggaacag atgtataaaa
      601 aattaaaatt aaccacaata agcgaattga ttaaaaatat ttattgttca ttatccgttc
      661 tcatcattgg ttgtgcgtca gcttatgccg ttgaattcaa caaagattta atcgaagccg
      721 aagatcgtga aaacgttaac ctttcccaat ttgaaactga tggccaatta cccgtaggta
      781 aatactcatt aaacgctctt attaataata aaaggacgcc aatccatctg gacctgcaat
      841 gggtattaat tgataaccaa actgcagttt gtctgactcc agagcaatta acattattag
      901 gctttactga tgagattatt gaagtggctc agcaaaacct gatcgatggt tgttacccta
      961 tcgaaaaaga aaaacaaatt acaacttatc tcgataaagg gaaaatgcaa ttatccatat
     1021 ctgcacctca ggcatggtta aaatacaaag atgcaaactg gacgcctcct gaactttggg
     1081 atcatggtat tgctggggca tttcttgact acaatttata tgcctctcat tatgcaccac
     1141 atcagggcga taattcacaa aatataagtt cctatgggca ggctggggtt aatcttgggg
     1201 cctggcgcct gcgtactgat taccagtacg atcaatcatt taacaatggc aaaagccagg
     1261 cgaacaacct ggattttccg cgtatttatt tgtttcgccc aatcccagca attaatgcaa
     1321 aactaactat aggtcaatac gatactgaat cctctatttt cgactctttc catttttctg
     1381 gcgtttcgtt gaaaagcgat gagaatatgt tgccgcctga tctacgtggt tacgcaccgc
     1441 aaatcacggg tgttgcacaa acgaatgcaa aggtcactgt ctcacagaac aaccgtatta
     1501 tttatcaaga aaatgttcct cctggcccat ttgctattac taatttattc aatacattac
     1561 aggggcaact ggacgtcaag gttgaagaag aggacgggca agtcacgcaa tggcaagttg
     1621 catctaatag tattccttat ctgacgcgta aagggcagat tcgctacacc actgctatgg
     1681 gtaaaccgac cagcgttggt ggtgattcct tacaacaacc cttcttctgg actggtgaat
     1741 tctcatgggg ttggctgaac aatgtatccc tgtatggtgg ttcagtttta acaaaccgtg
     1801 attatcaatc tctggctgcc ggcgttggct ttaaccttaa ctcattgggt tcattatctt
     1861 ttgatgtcac acgatctgat gctcagttgc ataatcagga taaagaaacg ggttatagct
     1921 accgcgctaa ctattcaaaa cgttttgaat ctaccggtag ccagctcact ttcgctggtt
     1981 accgtttctc tgataaaaac tttgtgacaa tgaatgaata tatcaatgac actaaccatt
     2041 acacgaatta tcagaatgaa aaagagagtt atattgtcac gtttaaccag tatcttgaat
     2101 cattaaggtt aaatacatac gtaagtttgg ctcgtaatac ttactgggac gccagcagta
     2161 atgtgaatta ttcattatca cttagccgcg attttgatat cgggccatta aaaaacgtct
     2221 ccacttctct aacatttagc cgaataaact gggaagaaga caaccaggat caactgtacc
     2281 taaatatttc gattccctgg ggaaccagta gaacattgag ctatggtatg caacgaaatc
     2341 aggataacaa gatttcgcat actgcttcgt ggtatgactc ttccgatcga aataattcct
     2401 ggagcgtttc tgcttcaggc gacaatgatg aattcaaaga tatgaaagcg tcactacgcg
     2461 ccagttatca gcataatacc gagaacggtc gtctctatct ctccgggaca tcacagcgag
     2521 acagttatta ttctctgaat gccagttgga atggttcatt cacggcgact cgtcacggag
     2581 ccgctttcca tgactatagt ggtagtgctg actcgcgttt tatgatcgac gcagatggtg
     2641 cagaagatat tccgttgaac aataaacgcg cggtaactaa tcggtatggc atcggagtta
     2701 ttccatcagt cagcagttac ataacaacat cattaagcgt tgatacccga aatcttccag
     2761 aaaatgtgga tatcgaaaac tcggttatca ccaccacctt aaccgaaggt gctattggct
     2821 acgccaaact tgatacccgc aagggctatc aaatcatggg ggttattcgc ctggcagatg
     2881 gtagtcaccc accactgggg attagcgtaa aagataaaac cagccataaa gaattaggac
     2941 tggttgctga tggcggcttt gtatacctca acggcattca ggatgacagc aaacttactt
     3001 tacgctgggg tgataaatcc tgttttattc aaccacccaa tagcagcaac ttaaccaccg
     3061 gaacggttat tttaccgtgt attagccaaa attaattcag gatgaaacta atgcgctact
     3121 taaacacaaa gaatctcatt gcagcaggag tattactcgc ctgcatgagc agcattgcct
     3181 ggggtgccat catcccggac cgtacccgta tcataatgaa tgagtcagat aaaggggaag
     3241 cattaaaact tactaatcaa agcaaaaatc taccctatct ggcgcaaaca tggatagaag
     3301 atacgaaagg caataaatca cgtgacttta ttgtcacggt tccccctatg gtacgtttaa
     3361 atcccagtga gcaaattcaa ataagaatga taagtcagga aaaaattgct caactgccta
     3421 atgacagaga aacgctcttc tattttaacg tgcgagaaat accgccaaaa acagataaaa
     3481 aaaatgtgat gcaagtcact atgcagcacg cattgaaact attctggcga ccaaaagcta
     3541 ttgaattaga agatgatggg gtaatgtctt acgaaaaagt tgaaatcatc cgtagaaatg
     3601 atggttcgat ccgctttaac aataagatgc cttatcacgt tacgctgggt tatatcggaa
     3661 caaacggaat cacaatgttg ccacaaacgc aaagtttaat ggtaacccct tatagccatg
     3721 cagatacgca gtttaaaaat gttccgtcag cttttcaggt tggttatatc aatgattttg
     3781 gtggattaag tttttatgaa ataaactgcc cgacggttaa taactcttgt aatgtttccg
     3841 tagccaaacg agata
//
LOCUS       DAPGUL010000232         3804 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.236, whole genome shotgun sequence.
ACCESSION   DAPGUL010000232 DAPGUL010000000
VERSION     DAPGUL010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3804)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3804)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3804
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.236"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            203..523
                     /locus_tag="RHX21_004701"
     CDS             203..523
                     /locus_tag="RHX21_004701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDV1989761.1"
                     /translation="MIAVIFEVQIQPDQQTRYLTLAEELRPLLSHVAGFISIERFQSL
                     ATEGKMLSLSWWENEYAVLQWKNHVLHAKAQQEGRESIFDFYKISIAHITREYSFKKD
                     KDNV"
     gene            516..902
                     /locus_tag="RHX21_004702"
     CDS             516..902
                     /locus_tag="RHX21_004702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid-binding protein"
                     /protein_id="HDV1989762.1"
                     /translation="MFDVHVVLDNQIGQLALLGKTLGNKGIGLEGGGIFTVGDECHAH
                     FLVEQGKEAKIALEQAGLLVLAIRTPLIRKLKQEKPGELGEIARVLAENNINILVQYS
                     DHANQLILITDNDSMAASVTLPWAIK"
     gene            910..1596
                     /locus_tag="RHX21_004703"
     CDS             910..1596
                     /locus_tag="RHX21_004703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDV1989763.1"
                     /translation="MANLIRKEVTFESSIAAIGAAMSDISRVKILSALMDGRAWTATE
                     LSSVANISASTASSHLSKLLDCQLITVVAQGKHRYFRLAGKDIAELMESMMGISLNHG
                     VHAKVSTPVHLRKARTCYDHLAGEVAVKIYDSLCQQQWITENGSMITLSGIQYFHEMG
                     IDVPSKHSRKICCACLDWSERRFHLGGYVGAALFSLYESKGWLTRHLGYREVTITEKG
                     YAAFKTHFHI"
     gene            complement(1574..2197)
                     /gene="tetR(B)"
                     /locus_tag="RHX21_004704"
     CDS             complement(1574..2197)
                     /gene="tetR(B)"
                     /locus_tag="RHX21_004704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional
                     repressor TetR(B)"
                     /protein_id="HDV1989764.1"
                     /translation="MSRLDKSKVINSALELLNEVGIEGLTTRKLAQKLGVEQPTLYWH
                     VKNKRALLDALAIEMLDRHHTHFCPLEGESWQDFLRNNAKSFRCALLSHRDGAKVHLG
                     TRPTEKQYETLENQLAFLCQQGFSLENALYALSAVGHFTLGCVLEDQEHQVAKEERET
                     PTTDSMPPLLRQAIELFDHQGAEPAFLFGLELIICGLEKQLKCESGS"
     gene            2279..3484
                     /gene="tet(B)"
                     /locus_tag="RHX21_004705"
     CDS             2279..3484
                     /gene="tet(B)"
                     /locus_tag="RHX21_004705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001089064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(B)"
                     /protein_id="HDV1989765.1"
                     /translation="MNSSTKIALVITLFDAMGIGLIMPVLPTLLREFIASEDIANHFG
                     VLLALYALMQVIFAPWLGKMSDRFGRRPVLLLSLIGASLDYLLLAFSSALWMLYLGRL
                     LSGITGATGAVAASVIADTTSASQRVKWFGWLGASFGLGLIAGPIIGGFAGEISPHSP
                     FFIAALLNIVTFLVVMFWFRETKNTRDNTDTEVGVETQSNSVYITLFKTMPILLIIYF
                     SAQLIGQIPATVWVLFTENRFGWNSMMVGFSLAGLGLLHSVFQAFVAGRIATKWGEKT
                     AVLLGFIADSSAFAFLAFISEGWLVFPVLILLAGGGIALPALQGVMSIQTKSHQQGAL
                     QGLLVSLTNATGVIGPLLFAVIYNHSLPIWDGWIWIIGLAFYCIIILLSMTFMLTPQA
                     QGSKQETSA"
     gene            complement(3597..>3804)
                     /locus_tag="RHX21_004706"
     CDS             complement(3597..>3804)
                     /locus_tag="RHX21_004706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDV1989766.1"
                     /translation="ITGKVNAIVSKLIQENQLKAYDDDVLKNLLNGWFMHIAIHAKNL
                     KELADKKGQFIAIYRGFLLSLKDK"
BASE COUNT         1076 a          688 c          826 g         1214 t
ORIGIN      
        1 ctgtgatagc aaaaaataaa aaagtataaa taataaacaa aattataaga gaaggagaac
       61 atgataagcg caggccgagc aatttaaaga agtgtgatat acaacataaa acagcagcat
      121 gacctttcta tatttcgttg cttatcgaag tgttaatttt cgggtggatt actctgtttg
      181 ttgattaata acggagaaaa atatgattgc tgtaatattt gaggtgcaaa tacaacccga
      241 ccaacaaact cgctatttga ctttagctga ggagttaaga ccactattaa gtcatgtagc
      301 tggttttatt tcaattgaac gttttcaaag tctagctaca gaaggaaaaa tgttatcgct
      361 atcttggtgg gaaaacgaat acgcagttct gcaatggaaa aatcatgttt tacatgcgaa
      421 agctcaacaa gaagggcgag agtcaatatt tgatttttac aaaattagta ttgctcatat
      481 tactcgcgaa tattcattta aaaaggacaa ggataatgtt tgatgttcac gttgttttag
      541 ataatcaaat aggacaatta gcattactag gaaaaacatt aggtaataaa ggtattggat
      601 tggaaggggg agggatattt acggttggtg atgaatgcca tgctcatttt cttgttgaac
      661 aaggaaagga agctaaaata gcgctagagc aagctggact gttagtactt gcgatccgga
      721 caccattaat tcgtaagtta aaacaggaaa aaccggggga acttggcgaa atagcacgag
      781 tattggcgga gaataacatt aatattttag tgcaatacag tgaccatgct aaccaactga
      841 tattaataac ggacaatgat agtatggctg catctgttac gctcccttgg gcaataaagt
      901 gaacttgcga tggctaattt aatacgaaaa gaggttacct ttgagtcctc aatagccgcg
      961 ataggggcgg ctatgtctga catttcacga gttaaaatac tcagtgcttt gatggatggg
     1021 cgagcttgga cggccactga gctaagttct gtggcgaata tatcagcttc aacggcgagc
     1081 agtcatttat ctaaattatt agattgccag ctaatcacag tagtagctca aggcaagcat
     1141 cgttattttc ggctagcagg aaaagatatt gctgaattga tggaaagtat gatggggatc
     1201 tccttaaacc atggcgtaca tgccaaagtt tccacgccag tgcatttacg aaaagcacgt
     1261 acttgctatg atcatttagc tggcgaagtt gccgttaaga tctatgattc cctttgtcaa
     1321 cagcaatgga tcactgaaaa tggttcaatg atcacattaa gtggtattca atattttcat
     1381 gaaatgggaa ttgacgttcc ttccaaacat tcacgtaaaa tctgttgtgc gtgtttagat
     1441 tggagtgaac gccgtttcca tttaggtggg tacgttggag ccgcattatt ttcgctttat
     1501 gaatctaaag ggtggttaac tcgacatctt ggttaccgtg aagttaccat cacggaaaaa
     1561 ggttatgctg cttttaagac ccactttcac atttaagttg tttttctaat ccgcatatga
     1621 tcaattcaag gccgaataag aaggctggct ctgcaccttg gtgatcaaat aattcgatag
     1681 cttgtcgtaa taatggcggc atactatcag tagtaggtgt ttccctttct tctttagcga
     1741 cttgatgctc ttgatcttcc aatacgcaac ctaaagtaaa atgccccaca gcgctgagtg
     1801 catataatgc attctctagt gaaaaacctt gttggcataa aaaggctaat tgattttcga
     1861 gagtttcata ctgtttttct gtaggccgtg tacctaaatg tacttttgct ccatcgcgat
     1921 gacttagtaa agcacatcta aaacttttag cgttattacg taaaaaatct tgccagcttt
     1981 ccccttctaa agggcaaaag tgagtatggt gcctatctaa catctcaatg gctaaggcgt
     2041 cgagcaaagc ccgcttattt tttacatgcc aatacaatgt aggctgctct acacctagct
     2101 tctgggcgag tttacgggtt gttaaacctt cgattccgac ctcattaagc agctctaatg
     2161 cgctgttaat cactttactt ttatctaatc tagacatcat taattcctaa tttttgttga
     2221 cactctatca ttgatagagt tattttacca ctccctatca gtgatagaga aaagtgaaat
     2281 gaatagttcg acaaagatcg cattggtaat tacgttattc gatgccatgg ggattggcct
     2341 tatcatgcca gtcttgccaa cgttattacg tgaatttatt gcttcggaag atatcgctaa
     2401 ccactttggc gtattgcttg cactttatgc gttaatgcag gttatctttg ctccttggct
     2461 tggaaaaatg tctgaccgat ttggtcggcg cccagtgctg ttgttgtcat taataggcgc
     2521 atcgctggat tacttattgc tggctttttc aagtgcgctt tggatgctgt atttaggccg
     2581 tttgctttca gggatcacag gagctactgg ggctgtcgcg gcatcggtca ttgccgatac
     2641 cacctcagct tctcaacgcg tgaagtggtt cggttggtta ggggcaagtt ttgggcttgg
     2701 tttaatagcg gggcctatta ttggtggttt tgcaggagag atttcaccgc atagtccctt
     2761 ttttatcgct gcgttgctaa atattgtcac tttccttgtg gttatgtttt ggttccgtga
     2821 aaccaaaaat acacgtgata atacagatac cgaagtaggg gttgagacgc aatcgaattc
     2881 ggtatacatc actttattta aaacgatgcc cattttgttg attatttatt tttcagcgca
     2941 attgataggc caaattcccg caacggtgtg ggtgctattt accgaaaatc gttttggatg
     3001 gaatagcatg atggttggct tttcattagc gggtcttggt cttttacact cagtattcca
     3061 agcctttgtg gcaggaagaa tagccactaa atggggcgaa aaaacggcag tactgctcgg
     3121 atttattgca gatagtagtg catttgcctt tttagcgttt atatctgaag gttggttagt
     3181 tttccctgtt ttaattttat tggctggtgg tgggatcgct ttacctgcat tacagggagt
     3241 gatgtctatc caaacaaaga gtcatcagca aggtgcttta cagggattat tggtgagcct
     3301 taccaatgca accggtgtta ttggcccatt actgtttgct gttatttata atcattcact
     3361 accaatttgg gatggctgga tttggattat tggtttagcg ttttactgta ttattatcct
     3421 gctatcgatg accttcatgt taacccctca agctcagggg agtaaacagg agacaagtgc
     3481 ttagttattt cgtcaccaaa tgatgttatt ccgcgaaata taatgaccct cttgataacc
     3541 caagagggca ttttttacga taaagaagat ttagcttcaa ataaaaccta tctattttat
     3601 ttatctttca agctcaataa aaagccgcgg taaatagcaa taaattggcc ttttttatcg
     3661 gcaagctctt ttaggttttt cgcatgtatt gcgatatgca taaaccagcc attgagtaag
     3721 tttttaagca catcatcatc ataagcttta agttggttct cttggatcaa tttgctgaca
     3781 atggcgttta ccttaccagt aatg
//
LOCUS       DAPGUL010000233         3668 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.238, whole genome shotgun sequence.
ACCESSION   DAPGUL010000233 DAPGUL010000000
VERSION     DAPGUL010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3668
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.238"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..105)
                     /locus_tag="RHX21_004707"
     CDS             complement(<1..105)
                     /locus_tag="RHX21_004707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus Gp2 family protein"
                     /protein_id="HDV1989767.1"
                     /translation="MTYKYNPFWQQRIRETVRHALNVHPRLTALRVDLR"
     gene            complement(97..183)
                     /locus_tag="RHX21_004708"
                     /pseudo
     CDS             complement(97..183)
                     /locus_tag="RHX21_004708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001375328.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus Gp2 family protein"
     gene            complement(850..993)
                     /locus_tag="RHX21_004709"
                     /pseudo
     CDS             complement(850..993)
                     /locus_tag="RHX21_004709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453335.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin activation protein"
     gene            1734..1940
                     /locus_tag="RHX21_004710"
     CDS             1734..1940
                     /locus_tag="RHX21_004710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000235222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
                     /protein_id="HDV1989768.1"
                     /translation="MATPVSLMDDQMVDMAFITQLTGLTDKWFYRLIRDGAFPAPIKL
                     GRSSRWLKSEVEAWLQARIAQPRP"
     gene            2035..2637
                     /locus_tag="RHX21_004711"
     CDS             2035..2637
                     /locus_tag="RHX21_004711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989769.1"
                     /translation="MKQQYQTRYEWLHESYQKWLTGFTRHAVSWGVCHPNIYYFHNLT
                     PGWVSFNGEKPEIAIVPQSLHRLIYGPDKRATPPLDDDLIVNLCTSEHLLVHHPMLEG
                     ILLSECERLRQRSLANKLISLFRQFGGTELRLKLVWLCWLDLMTGNSLEDWKENLKRK
                     SEKELEEWIINRQRQSAALTDLMDQYVLLAYRTTVDDSRN"
     gene            2994..3668
                     /locus_tag="RHX21_004712"
                     /pseudo
     CDS             2994..3668
                     /locus_tag="RHX21_004712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611435.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          870 a          971 c          927 g          900 t
ORIGIN      
        1 acgcaggtca acccgcaatg ccgtcaggcg gggatgaaca ttcagtgcgt gccgcaccgt
       61 ctcacgaata cgttgctgcc agaaggggtt gtatttgtag gtcatggtta aatctccgta
      121 tggttcatac ggaatagcca cgtcgtaaaa aatacgcaga gtccctgaag tgacctccgg
      181 caggacactg tctcaggcac tctgtgataa cccgaacggt cgtctccgga ctgacggttg
      241 aattttcagc gtcgtttttt aatgtaaaaa accggttacg ggtaaggctg tgaggaggga
      301 gtgatggtga tacgcaaaaa gaagtgcagg gactgtggaa acgcgattac tcataataca
      361 gtgtgttgcc cgtattgtgg ttctgtcgac cccttcggct actaccggaa tacagaccgt
      421 atcgttacca tactgctggc gctgattatt gtggtcctgc tgactactgt cagcgtcagt
      481 gtgtgtatac tgtgtagctg gtgagataac ggttcatgta tcccctgagc tgacagtgta
      541 ccgtgtatat taagcgtaac cgacaggttc tccttcatac catattaaat tttccaggga
      601 ttgccgctgc cttatttcgt cccatacagg aaaactcatc tgggtttctg acaaatacgc
      661 gaaactcaca gcccctcaat atcaaccaca cgttgtaagc cggtaatacc tgaaaatcag
      721 cctattaccg cccacgcctc cggcaccatt cccttttgat ttcgaattct ttgttgtcgc
      781 tataccgctt aatgttcccg gtcctccggt gcagataaca ccggagtcat cgtagcgctg
      841 cttcaatatt caggtgacat atttccagac ggaagccggc gcgcgatcgt aaagtttgtt
      901 cattgtcagt tctgccagcc ggttgtcaac ggcagagtta aaggcttcca gctccgcaag
      961 ggtaagttta taacgcgtgt gggaattcac ttttcccgcg tctcctgacg tattacgggc
     1021 tgccacttac ctggtgtccc gcaatacagc cttagtgttc cgttatcggg gatccggacg
     1081 caccgcaaca accggggaag tatttctggt ttagagcagt gtcaagaggg atttctcagc
     1141 ccctcactca ccggctcagt ctcagggcag gagcattaat acgctcagtt catgtcttat
     1201 acaggaatgg gcacaggggg agctggcgtg tcactgctga ttttacgcat cagcgttcat
     1261 gtatctgcac tctgatacat gaacgattca cagcgctctg ttaccggaga gatttactct
     1321 cttagcttac tctggcaaat cctttacgtt actctctgat gacttcttat atttataata
     1381 ccaatcagac agccttatcc catcggtgat atcagtctcc tcctcgccag gaacgggctg
     1441 actcactgta accacctccg aaaacaactc tgcaattatc agaacgcctg cttctctccc
     1501 tgtcctcacg aaaactatcc cctctttatc gcgcgtgcgt gcggaagcat cttttcgcaa
     1561 caaccacccg gtataccggt acggctcagc caccgcaacc tccccgttta tctcctggcg
     1621 gtcacattcc cgattatttt ttacgtttct ccccggttgt tatgccggtg aaggtggcgc
     1681 gctgttttca tgaccacacc ggctggttta acaacatccg gaggaacatt ctcatggcta
     1741 ccccagtttc actgatggat gaccagatgg tcgacatggc atttatcact caactgaccg
     1801 gcctgacaga taagtggttt tacaggctca tcagggatgg ggcctttccg gctcccatca
     1861 agctgggccg cagctcccgc tggctgaaaa gtgaagtgga agcctggcta caggcgcgta
     1921 ttgcacagcc ccgcccgtaa tttctgaccg ttatccgttc acccgcagca gacgtaatcc
     1981 ccggcctgcc ggcggcattc tgctgcctgt tatatccccg tgaggaatat gaaaatgaaa
     2041 caacagtatc agacccgcta cgaatggctc cacgaaagct accagaaatg gctgaccggc
     2101 ttcacccggc acgccgtatc ctggggcgtg tgtcatccga atatctacta cttccataat
     2161 ctgacgcccg gttgggtgtc attcaatggt gaaaaaccgg agattgccat cgtaccccag
     2221 agcctgcacc ggctgattta tggccctgac aaacgggcca cgccgcccct ggatgatgat
     2281 ctgatagtga atttatgcac cagtgaacat ctgctggttc atcatccgat gctggaaggc
     2341 attctcctgt ctgaatgtga acgtctgagg cagcgttctc tggcaaataa actgatcagc
     2401 ctcttccgtc agtttggtgg cacggagttg cgcctcaaac tggtctggct ttgctggctt
     2461 gatttaatga ccggaaacag ccttgaagac tggaaagaga acctgaaacg gaaatcagaa
     2521 aaagagctgg aggaatggat catcaaccgt cagaggcaga gcgcagcact gacggatctg
     2581 atggatcagt acgtgctcct ggcataccgc acaacggttg acgatagccg caactgatgc
     2641 cggttgcttc cggaaggtgt gacaaaatac ggaaatgatg atgctcccgg cccccatgct
     2701 cacctgcaga gcgtgttcgt cgtcatcata ctgagccatg acgggcgtct taagggcatc
     2761 ctgtcattgc tgagcaggca acaccaccag aggagccacg gacagggatg ttctttacag
     2821 cccgatacac gccaggttct cagcagactg aatgtgcagg tgcggttatt caccagaaat
     2881 ggcatgctgc ggtacatacc catcctggtg acaatatgta cgtggcgaca gcgatcccgg
     2941 cactgtgtag actggccccc tgaatctcca gacaaccaat atcacttatt taagtgatag
     3001 tcttaatact agtttttaga ctagtcattg gagaacagat gattgatgtc ttagggccgg
     3061 agaaacgcag acggcgtacc acacaggaaa agatcgcaat tgttcagcag agctttgaac
     3121 cggggatgac ggtcaccctc gttgcccggc aacatggtgt agcagccagc cagttatttc
     3181 tctggcgtaa gcaataccag gaaggaagtc ttactgctgt cgccgccgga gaacaggttg
     3241 ttcctgcctc tgaacttgct gccgccatga agcagattaa agaactccag cgcctgctcg
     3301 gcaagaaaac gatggaaaat gaactcctca aagaagccgt tgaatatgga cgggcaaaaa
     3361 agtggatagc gcacgcgccc ttattgcccg gggatgggga gtaagcttag tcagccgttg
     3421 tctccgggtg tcgcgtgcgc agttgcacgt cattctcaga cgaaccgatg actggatgga
     3481 tggccgccgc agtcgtcaca ctgatgatac ggatgtgctt ctccgtatac accatgttat
     3541 cggagagctg cccacgtatg gttatcgtcg ggtatgggcg ctgcttcgca gacaggcaga
     3601 acttgatggt atgcctgcga tcaatgccaa acgtgtttac cggatcatgc gccagaatgc
     3661 gctgttgc
//
LOCUS       DAPGUL010000234         3581 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.239, whole genome shotgun sequence.
ACCESSION   DAPGUL010000234 DAPGUL010000000
VERSION     DAPGUL010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3581)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3581)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3581
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.239"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..752
                     /locus_tag="RHX21_004713"
     CDS             <1..752
                     /locus_tag="RHX21_004713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDV1989770.1"
                     /translation="KQSDERLKLEIKVAHISTRETYGTRRLQTELAENGIIVGRDRLA
                     RLRKELRLRCKQKRKFRATTNSSHNLPVAPNLLNQTFAPTVPNQVWVADLTYVATQEG
                     WLYLAGIKDVYTCEIVGYAMGERMTKELTGKAMFMALRSQRPPAGLIHHSDRGSQYYA
                     YDYRVIQEQFGLKTSMSRKGNCYDNAPMESFWGTLKNESLSHYRFNSRDEAISVIREY
                     IEIFYNRQRRHSRLGNISPAAFREKYHQMAA"
     gene            complement(1296..2321)
                     /locus_tag="RHX21_004714"
     CDS             complement(1296..2321)
                     /locus_tag="RHX21_004714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HDV1989771.1"
                     /translation="MKVKAVYINKPGEIATRLVDYPVRKDNEVLIKVDAAGICGSDIG
                     AFRGTNPLVTYPRIIGHEVTGIVLETGEGVPQNIKQGDRVIVDPYVYCGHCYPCSVGR
                     TNCCENLKVIGVHIDGAMQEVVSHPAHLIHKIPDNVPSEMAPLAEPLTIALHALHRAQ
                     LKAGEHVVIIGAGAIGLMAALSSLNYKATPILVDIVDERLQYAKSLGVPYVVNSAKAN
                     VIEAVKDITQGTMAQVVVEASGANSAIRSTLDLASFAGRIAYTGWPKQETSLPTNLIT
                     FKELDLRGSRTSAGEFEEALQMLSTLNINPADIVSKVVTIDEVPEAVKELDQFPERYL
                     KINVKFI"
     gene            complement(2293..3528)
                     /locus_tag="RHX21_004715"
     CDS             complement(2293..3528)
                     /locus_tag="RHX21_004715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002431397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDV1989772.1"
                     /translation="MLNYMDRSALSITAPLIEKELGFNAAEMGMIFSAFFVGYALFNF
                     IGGWASDKVGPKTVFLVAALLWSVFCGMTGLVTGLWTMLAVRVLFGMAEGPVSAAGNK
                     IINNWISRKESATAIGIFSAGSPLGGAISGPVVGLLAISLGWRPAFGIIFIFGLVWVL
                     LWYFFVSDKPSKSKRLAAEERVDFENHDDIILAEDGKGTPSLGYYMKQPMVWATTLAF
                     FSYNYILFFFLTWFPSYLNHSLHIDIKEISIATVIPWFIGAIGMVLGGVCSDFIYRIT
                     GNALLSRRLILGSCLAGAAVCVAVSGTVTSIGSAITLMSVSLFLLYLTGPIYWAVIQD
                     VVHKDKVGSVGGAMHGLANISGIIGPLVTGFIVQFSGKYDYAFYLAGAIAIISSLLVF
                     IFVKNKGLKVNESQSCVHQ"
BASE COUNT         1034 a          890 c          755 g          902 t
ORIGIN      
        1 gaaaacaaag tgatgagcgg ctaaaactgg agattaaggt ggcacatatc agcactcgcg
       61 aaacatatgg aacccggcgg ctccagacgg agctggcaga gaatggcatc atcgttggtc
      121 gtgaccgact ggcacgtctt cgtaaggagc taaggctacg ctgtaagcag aaacgcaagt
      181 tcagagcgac tacgaactcg agccacaatc tgccagttgc gccaaatctg ctgaaccaga
      241 cgttcgctcc tacagtacca aatcaggtct gggtggcgga cctgacgtat gttgccacac
      301 aggagggatg gttgtacctc gctggcatca aagatgttta tacgtgcgaa attgtcggct
      361 acgccatggg agagcgcatg acaaaagagc tgacaggtaa agccatgttt atggcgctca
      421 ggagccagcg cccacctgcc gggctaatcc accactccga tcgaggttca cagtactacg
      481 catacgatta ccgggtcatc caggagcagt ttggtctgaa aacatcaatg tcgcgtaaag
      541 gtaactgtta cgacaacgct ccgatggaaa gcttctgggg aacgctgaaa aatgagagcc
      601 tgagccacta tcgttttaat agccgggatg aggccatctc agtaatacgg gaatacattg
      661 agattttcta caatcgtcag cgtcgtcact ctcgtctggg gaatatctcc ccggcagcct
      721 tcagggaaaa atatcatcag atggctgctt aaaaaaagaa caaatggtag tgtccgctat
      781 tgccagtaca cctcaggatg ccgtccgtct cttctgccgc tggccgcagt tgcctgcgtt
      841 tatgcttcat taatcatcat cgggttcgga tgtcctaatc acggttaatt atgttcggcc
      901 cttcatgctg ccggttttgc agcgctacta cggcgtcggt agcacactgg cagagcggca
      961 gatctcccgg ggtaattcgc acgactttcc tgcttatgcc tgtcggctgt acgtcaccgc
     1021 gttccgtgtg agtattgggc tttggtgatt tgtgccgcct tagccgcttc ctgttcgtca
     1081 ggccagcatt ttgcatccgg cttccttcag atttcacctc gcgatgaaca tccttgcctt
     1141 ccgctaacat ttcccctcac cgggtgtttg gagaactttc acctcttagt cgttcttcag
     1201 ccaccacagt tgaagaacag cgccagtcac ggcgcacaca aaaaacgcgt agtgaataca
     1261 ctacgcgtca gactttttat ttttgttaat tataattaaa tgaatttcac gttaattttc
     1321 agatagcgtt ccggaaattg atctaactct tttacagcct caggaacttc atctattgtc
     1381 acgactttgc tcacgatatc agccggatta atattcagcg ttgataacat ttgcagggct
     1441 tcttcaaatt caccggcact ggtacgggaa ccacgtaaat ctagttcttt aaaggtaatt
     1501 agattagttg gtaacgatgt ttcctgcttt ggccaaccag tataggctat acgccctgca
     1561 aatgaggcca gatccagggt acttctgatt gcgctatttg caccagaggc ttccaccaca
     1621 acctgagcca tcgtcccttg tgtaatatct ttcactgcct caataacatt agcttttgcg
     1681 gagtttacta cataaggtac gccgagcgat ttcgcgtatt gcaaccgttc atcgacaata
     1741 tcaaccagaa tgggagttgc tttatagttc aacgaactca gggccgccat aagtccaata
     1801 gcgcctgcac caataatgac gacatgttca cctgctttca attgcgctcg atgtaatgcg
     1861 tgtagggcaa tagttaaggg ttcagccagt ggcgccatct ctgacggtac attgtcagga
     1921 attttgtgaa ttaagtgagc cggatgcgaa accacttctt gcatagcgcc atcaatatgt
     1981 acgccgatga cttttaagtt ctcgcagcaa ttagttctac ctacagaaca tggataacag
     2041 tgaccgcaat aaacataggg atctacaata acccggtcgc cctgtttgat attttgtggt
     2101 accccctcac cggtttccag aacaatcccg gtgacttcat gtccaataat tctcggataa
     2161 gttaccagtg ggttagtacc acgaaatgca ccgatgtcag aaccacaaat tcccgctgca
     2221 tccactttaa ttaaaacttc attatctttt cttactggat aatcgaccag acgggtagca
     2281 atttcaccag gtttattgat gtacacagct ttgactttca ttgactttca atcctttatt
     2341 tttaacaaaa atgaatacca gcagacttga aatgattgct atggcacctg caagatagaa
     2401 tgcgtaatca tatttaccac tgaactggac aataaaaccg gttaccaatg gaccaataat
     2461 gccggaaata tttgccagac cgtgcatcgc accgcctacg ctacctactt tatctttatg
     2521 cactacatcc tgaataacag cccaataaat aggtccagtt agataaagca ggaataagga
     2581 aacagacatc agcgtaatcg cactaccaat agaggtaaca gttccggaaa cagcgacaca
     2641 aaccgcggcc cccgcaaggc aactgccgag aattaaacgg cgagaaagta aggcatttcc
     2701 cgtaatacga taaataaagt cagagcagac gccacctaac accatgccaa ttgccccaat
     2761 aaaccacggg ataacagttg caatactaat ttctttaata tcaatgtgta atgaatgatt
     2821 caaatagctt ggaaaccaag taagaaagaa aaatagaata tagttatagc taaaaaatgc
     2881 cagcgtggtc gcccatacca tcggctgctt catgtaataa ccaagcgaag gtgtaccttt
     2941 accatcttcg gctagaataa tatcgtcatg gttttcgaaa tcgacacgtt cttccgctgc
     3001 cagacgttta ctttttgacg gtttatcact gacaaagaag taccacagta atacccaaac
     3061 taggccaaat ataaatatga tcccaaacgc cggacgccag ccaagtgata ttgccagcaa
     3121 gccaacgacc ggaccagaaa tagcgccacc aagtggtgaa ccagcactaa aaataccgat
     3181 agctgttgcc gactctttac gcgagatcca gttattaata attttatttc ctgctgcact
     3241 aaccgggccc tctgccatac caaataaaac acgtacggca agcattgtcc ataatccggt
     3301 gaccagaccg gtcataccac aaaaaacaga ccacaacagt gcagcaacca aaaatactgt
     3361 tttgggtcca actttgtcac tggcccaacc gccaatgaag ttaaataaag cataaccaac
     3421 gaaaaatgcg ctgaaaatca tccccatttc agcagcatta aagcctaact ctttttcgat
     3481 aagtggggcc gtaatcgata atgcagaacg atccatatag ttcagcatgt aaactataaa
     3541 cagaagaaaa acgataatcc accccatggt ttttcttttc a
//
LOCUS       DAPGUL010000235         3502 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.240, whole genome shotgun sequence.
ACCESSION   DAPGUL010000235 DAPGUL010000000
VERSION     DAPGUL010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3502
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.240"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            163..1683
                     /locus_tag="RHX21_004716"
     CDS             163..1683
                     /locus_tag="RHX21_004716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418214.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
                     /protein_id="HDV1989773.1"
                     /translation="MSLSIVHTRAALGVNAPPITVEVHISKGLPGLTMVGLPETTVKE
                     ARDRVRSAIINSGYEYPAKKITINLAPADLPKEGGRYDLPIAIALLAASEQLTANKLD
                     EYKLVGELALTGALRGVPGAISSATEAIKSGRKIIVAKDNEDEVGLINGEGCLIADHL
                     QAVCAFLEGKHALERPKPTDAVSRALQHDLSDVIGQEQGKRGLEITAAGGHNLLLIGP
                     PGTGKTMLASRINGLLPDLSNEEALESAAILSLVNAESVQKQWRQRPFRSPHHSASLT
                     AMVGGGAIPGPGEISLAHNGVLFLDELPEFERRTLDALREPIESGQIHLSRTRAKITY
                     PARFQLVAAMNPSPTGHYQGNHNRCTPEQTLRYLNRLSGPFLDRFDLSLEIPLPPPGI
                     LSKTVVPGESSATVKQRVMAARERQFKRQNKLNAWLDSPEIRQFCKLESEDAMWLEGT
                     LIHLGLSIRAWQRLLKVARTIADIDQSDIITRQHLQEAVSYRAIDRLLIHLQKLLT"
     gene            complement(1708..2046)
                     /gene="maoP"
                     /locus_tag="RHX21_004717"
     CDS             complement(1708..2046)
                     /gene="maoP"
                     /locus_tag="RHX21_004717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrodomain Ori organization protein MaoP"
                     /protein_id="HDV1989774.1"
                     /translation="MAESFTTTNRYFDNKHYPRGFSRHGDFTIKEAQLLERHGYAFNE
                     LDLGKREPVTEEEKLFVAVCRGEREPVTEAERVWSKYMTRIKRPKRFHTLSGGKPQVE
                     GAEDYTDSDD"
     gene            2165..3004
                     /gene="hdfR"
                     /locus_tag="RHX21_004718"
     CDS             2165..3004
                     /gene="hdfR"
                     /locus_tag="RHX21_004718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator HdfR"
                     /protein_id="HDV1989775.1"
                     /translation="MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLG
                     VNLFTRHRNNIRLTAAGEKLLPYAETLMSTWQAARKEVAHTSRHNEFSIGASASLWEC
                     MLNQWLGRLYQNQDAHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQL
                     LGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQ
                     IAMLNGCTWLPVSWARKKGGLHTVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLD
                     EVY"
     gene            complement(3100..3175)
                     /locus_tag="RHX21_004719"
     tRNA            complement(3100..3175)
                     /locus_tag="RHX21_004719"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3140..3142),aa:Trp,seq:cca)
     gene            complement(3184..3260)
                     /locus_tag="RHX21_004720"
     tRNA            complement(3184..3260)
                     /locus_tag="RHX21_004720"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(3224..3226),aa:Asp,seq:gtc)
     gene            complement(3315..3430)
                     /gene="rrf"
                     /locus_tag="RHX21_004721"
     rRNA            complement(3315..3430)
                     /gene="rrf"
                     /locus_tag="RHX21_004721"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          923 a          872 c          859 g          848 t
ORIGIN      
        1 tagttcatcc tttgtccgct gcatttttgc gagcatcatt ccaccgccag aacaactcaa
       61 cttcacttgc acaaataaac aggaatcagc cactaaaatt cacgaattag cgggctacag
      121 cagcgatatc ttatgcacat aatggtgact caaggagggc ttatgtcact gtcaattgtt
      181 catacccgcg cagccctggg agtaaatgcg cccccgatca ctgttgaggt acatatcagt
      241 aaaggtctac ccggcttaac gatggtgggc ttaccagaaa caacggtaaa agaagctcgc
      301 gatcgcgtgc gcagcgccat tatcaatagc ggatatgaat atccggcgaa aaaaatcacc
      361 atcaacctgg ctccagctga tctgccaaaa gaagggggac gatatgattt acctatcgcc
      421 attgcgttgc tggcggcctc agaacagctt acagccaata agttagatga atataaatta
      481 gtcggagaac tggcgcttac aggcgctctg cgtggcgttc ccggcgcaat ctccagtgca
      541 actgaagcta ttaagtcggg cagaaaaatt atcgtcgcga aagataacga agatgaagtg
      601 gggctaatta acggtgaagg atgcctgata gccgatcatc tgcaagctgt ctgtgcgttt
      661 ctggaaggta agcacgctct cgaacgcccg aaaccaactg atgcagtatc ccgggcgcta
      721 caacatgatc tcagtgatgt tatcggtcag gaacaaggaa agcgaggact ggaaattacc
      781 gctgctggcg ggcacaacct tttactgatt gggccgccgg gaacaggtaa aacaatgctc
      841 gccagccgta ttaatggcct gttgccagat ttaagcaatg aagaggcact ggagagtgct
      901 gcgatattaa gtctggtaaa tgctgaatca gtacaaaaac aatggcggca gcgcccgttc
      961 cgctcacctc atcacagtgc atcgttaact gcgatggtag gcggtggcgc aattccaggg
     1021 cccggtgaaa tttcgctggc gcataacggc gtgctttttc ttgatgagct acctgaattt
     1081 gaacggcgta cactggatgc cttgcgagag ccgattgaat ccgggcagat ccatctttca
     1141 cgcacacgag caaaaataac ctatccagcc cgtttccagc ttgttgcggc gatgaatccc
     1201 agccctaccg gacattatca gggaaaccat aaccgctgca cgccagaaca gacattacgt
     1261 tatctcaacc ggctctcggg gccctttctc gaccgcttcg atctctcact ggagatccca
     1321 ttaccacccc ccggcatttt gagtaaaacg gtagtgccgg gagaaagcag cgccaccgtt
     1381 aaacaacgcg taatggccgc cagagagcgc caatttaagc ggcagaataa actgaatgcc
     1441 tggctggata gtccggaaat acgccaattc tgcaaacttg agagcgaaga tgcgatgtgg
     1501 ttggaaggaa cactgatcca tctggggtta tcgattcgtg cctggcagcg gttattgaaa
     1561 gttgcacgaa ccattgctga tattgatcag tctgacatta tcacacgtca gcatttgcag
     1621 gaggcagtta gctatcgagc gattgaccgt ttgctcatcc atctgcagaa actactgaca
     1681 taaaaaaagg gcatttcgcc ctttttatta atcgtcagaa tcggtgtagt cttcagcacc
     1741 ttcaacctgc ggtttaccgc cggaaagggt gtgaaaacgt tttggacgct taatacgcgt
     1801 catatacttg gaccacacgc gttctgcttc tgtcactggc tcacgttcgc cacggcatac
     1861 tgctacgaag agtttctctt cctcggtaac cggctcgcgt ttgccaagat ccaactcatt
     1921 gaaggcataa ccatgacgct caagcagttg tgcctctttg atggtgaaat caccatgacg
     1981 agagaatcca cgtggataat gtttattgtc gaaatatcga ttagtcgtcg taaagctttc
     2041 cgccatcctg cacgctccta attctttgac cgagctagtt atggcgcgga gtattagtta
     2101 cgcttgacag agtgtaaaac aaaacattta aatcataacg acaaataatt ttgcggagag
     2161 cactgtggat acggaattgt taaaaacttt cctggaagtt agccgaacgc gtcactttgg
     2221 tcgagcggct gaatcgctct atctgaccca gtcagcagtg agctttcgaa tcagacaact
     2281 ggaaaatcaa ctgggtgtga accttttcac ccgccacaga aacaatatcc gtttaaccgc
     2341 tgccggtgaa aaactactgc cttatgcaga aacgctcatg agcacctggc aggccgcccg
     2401 taaggaggtg gcgcatacct cacgacataa cgagttttct atcggtgcca gcgcctcgtt
     2461 gtgggaatgt atgcttaatc agtggctggg acgcttgtat caaaatcagg atgcccatac
     2521 aggcttacag ttcgaagcgc gaattgccca acggcagtct ctggtaaaac agctgcatga
     2581 acgccagctt gatcttctta ttaccactga agcgcccaaa atggacgaat ttagtagtca
     2641 gttgctggga tatttcactt tagcgcttta taccagtgcc ccttcaaaac taaagggaga
     2701 tcttaattat ctgcgacttg agtgggggcc agattttcaa cagcatgagg caggtttgat
     2761 cggtgctgac gaagtgccca ttctgacaac cagttctgct gaactggcac agcaacagat
     2821 tgcgatgctt aatggttgca cctggctacc cgtcagctgg gcgcgtaaaa aaggcggcct
     2881 gcataccgtt gtcgatagca caacactttc acggccgctt tatgccatat ggctgcaaaa
     2941 tagcgataaa aatgcgttga ttcgcgatct tttgaaaatt aacgtgctgg atgaagtgta
     3001 ttaatatgaa tggctggcaa ggatgccggt agaaggattt acttcggaga gggttatttc
     3061 agataaaaaa aatccttagc tttcgctaag gatgatttct ggcaggggcg gagagactcg
     3121 aactcccaac acccggtttt ggagaccggt gctctaccaa ttgaactacg cccctaatta
     3181 gggtggcgga acggacggga ctcgaacccg cgaccccctg cgtgacaggc aggtattcta
     3241 accgactgaa ctaccgctcc accgaattct tttacaacca ccggttttat gaccggctta
     3301 ctgcttaatt tgatgcctgg cagttcccta ctctcgcatg gggagacccc acactaccat
     3361 cggcgctacg gcgtttcact tctgagttcg gcatggggtc aggtgggacc accgcgctac
     3421 ggccgccagg caaattctgt tttatcagac cgcttctgcg ttctgattta atctgtatca
     3481 ggctgaaaat cttctctcaa tc
//
LOCUS       DAPGUL010000236         3458 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.241, whole genome shotgun sequence.
ACCESSION   DAPGUL010000236 DAPGUL010000000
VERSION     DAPGUL010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3458
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.241"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(398..574)
                     /locus_tag="RHX21_004722"
                     /pseudo
     CDS             complement(398..574)
                     /locus_tag="RHX21_004722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611530.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(938..1096)
                     /locus_tag="RHX21_004723"
     CDS             complement(938..1096)
                     /locus_tag="RHX21_004723"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989776.1"
                     /translation="MMMSDTTLSRPEVVSGHTDVIYSTSVCHILAVRKSTLLPIDTII
                     RHQVSDIS"
     gene            complement(1196..1372)
                     /locus_tag="RHX21_004724"
     CDS             complement(1196..1372)
                     /locus_tag="RHX21_004724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF957 domain-containing protein"
                     /protein_id="HDV1989777.1"
                     /translation="MKSLTTETALDILITWLQDNIDCESGIIFDNDEDKTDSAALLPC
                     IAQAREGIRTLRQQ"
     gene            complement(1389..1877)
                     /locus_tag="RHX21_004725"
     CDS             complement(1389..1877)
                     /locus_tag="RHX21_004725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989778.1"
                     /translation="MKLALTLEADSVNVQALNMGRIVVDIDGVNLAELINMVCDNGYS
                     LRVVDESDRTSADCTPPFVALTGIRCSTAHITETDNAWLYSLSHQTSDFGESEWIHFT
                     GTGYLLRTDTWSYPVLRLKRLGLSKTFRRLVVTLIRCYGVSLIHLDASAGYLPGLPTF
                     DW"
     gene            complement(1874..2251)
                     /locus_tag="RHX21_004726"
     CDS             complement(1874..2251)
                     /locus_tag="RHX21_004726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin"
                     /protein_id="HDV1989779.1"
                     /translation="MKTLPDTHVREVSCCPSPVTIWQTLLTRLLDQHYGLTLNDTPFA
                     DERVIEQHIEAGISLCDAVNFLVEKYALVRTDLPGFSACTHSQLINSIDILRARRATG
                     LMIRDNYRTVNNITLGKHPEAKR"
     gene            complement(2341..2709)
                     /locus_tag="RHX21_004727"
     CDS             complement(2341..2709)
                     /locus_tag="RHX21_004727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system YeeU family
                     antitoxin"
                     /protein_id="HDV1989780.1"
                     /translation="MSDTLSGTTHPDDNDDHPWWGLPCTVTPCFGARLVQEGNRLHYL
                     ADRAGIRGRFRDADAYPLDQAFPLLMKQLKLMLTSGELNPRHQHTVTLYAKGLTCEAD
                     TLGSCGYVYLAVYPTPETKK"
     gene            complement(2872..3093)
                     /locus_tag="RHX21_004728"
     CDS             complement(2872..3093)
                     /locus_tag="RHX21_004728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 domain-containing protein"
                     /protein_id="HDV1989781.1"
                     /translation="MKIITRGEAMRIHRQHPASRLFPFCTGKYRWHGSAEAYTGREVQ
                     DIPGVLAVFAERRKDSFGPYVRLMSVTLN"
     gene            complement(3156..>3458)
                     /gene="radC"
                     /locus_tag="RHX21_004729"
     CDS             complement(3156..>3458)
                     /gene="radC"
                     /locus_tag="RHX21_004729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HDV1989782.1"
                     /translation="FRVLYLNNQNQLIAGETLFTGTINRTEVHPREVIKRALYHNAAA
                     VVLAHNHPSGEVTPSKADRLITERLVQALGLVDIRVPDHLIVGGSQVFSFAEYGLL"
BASE COUNT          850 a          856 c          903 g          849 t
ORIGIN      
        1 ggctttaact gttcctgata taagttgaca gttttctgtc cgtaaaacgg ttgatgaact
       61 tcatcgggcg ttttgtattt caatgccaaa tgtgaccgct catggttata aattgccacg
      121 aattctttta ccatttaccg gccctacgtc agctctgcag gacgcgagag taaaaactca
      181 ttttcaggat tccgtttatc cactcagcct gcgcattctg gtggcagtta taaccattag
      241 tcattgaaca ggttattgat aaataattaa aaaactcagt tttctggctc gcctgctcaa
      301 gctgttcttc aagttccctg attctttgct cgggtgtcag cgggacagtc gccagagcca
      361 caggcagtct cctctttacc tggtcaggaa gtccggggct ccagtcaagc cggccatatt
      421 tacgcaacca gacaagaacg gtggagcgcc cctgaatgcc ataactgcag ccggcctgtt
      481 tataagtcat ctcgcctttt tcaaccttct caacaacggc tattttaaag gatagaggat
      541 aatcacgttg agtgcgtttg aacccagaca tcatcacgtt ctccgggttt aagtcaggaa
      601 cgtgtcatag ctattcagga cgggtcaccg acacaaaaaa agtcgccctt gagcgactcg
      661 atttgcatac ggtatggtgc gaaggccgga ctcaaacatg cgatttaacc tcatgattta
      721 aaattgttaa taataaacaa caccatccta taccaacaca gataccaaca cgaaaaatca
      781 ctggttttcg gcatcgaacc aggacaatca ggtcctgatt gagataccga gctctgttac
      841 tcgtcatctt cctcgacagg ctccattgca tcaagtggta ctcgcaccat cgcgatagaa
      901 ccaatccgga taaaagcatc ttccccatct atatcggtta actgatatcg cttacttgat
      961 gccggataat tgtgtcgatt ggcaacagtg tactctttcg tacagccaga atgtggcaga
     1021 ctgaggtgga atagataacg tccgtatgcc cgctgaccac ctccgggcgg gagagtgtgg
     1081 tatctgacat catcattttt cctttctgtt tataaatgaa aatgccagcc gtgttcaggc
     1141 tgacgtcagg gaagtgaaat cgggtgagtg atcttcactg gttctggtac aaaagttact
     1201 gttggcgcag ggtacggata ccctccctgg cctgtgcgat acagggcaac agtgctgccg
     1261 aatctgtttt atcctcatcg ttgtcgaaga taattcccga ttcgcagtcg atattgtcct
     1321 gcagccacgt aatcagaata tccagcgctg tttccgtggt taatgatttc atgttgtgaa
     1381 tttccggatt accagtcgaa agtgggtaaa cccggcagat atccggcact ggcatccaga
     1441 tgaatgagac tgacaccata acaccggatg agtgtgacga ccagacgacg gaacgttttt
     1501 gacagcccca ggcgcttaag ccgcagaacc gggtatgacc acgtatcggt acgtaacaga
     1561 taaccggtac cggtaaaatg aatccattct gattcaccga agtcactggt ctggtgtgac
     1621 agcgagtaca gccaggcgtt gtccgtttcc gtgatatgtg cggtactgca gcgtatgccg
     1681 gtaagggcaa caaatggtgg cgtgcagtct gctgaggtcc ggtcagattc atcaacaaca
     1741 cgaagggagt agccgttatc gcagaccatg ttaatcagtt cagcgagatt aacaccatca
     1801 atgtcaacga caatgcgccc catgttcagc gcctgcacgt taacgctgtc ggcttccagc
     1861 gtcagggcca gtttcatcgt ttcgcctccg gatgcttccc cagggtaatg ttatttaccg
     1921 ttctgtaatt gtcgcggatc atcaggcctg ttgcccggcg agcccggagg atatcgatgc
     1981 tgtttattaa ctgagagtgg gtacaggcgc tgaatcccgg caggtcggta cgtaccagtg
     2041 cgtatttttc cacgagaaag ttcactgcat cacacagtga aatgcctgcc tcaatatgct
     2101 gctcaatcac acgttcatca gcgaacggtg tgtcattcag cgtaaggccg tagtgctggt
     2161 ccagcagtcg ggtgagcagt gtctgccaga tggtgactgg agacgggcag cacgatacct
     2221 cccgtacatg cgtgtcgggt aatgttttca tactgaagat tttcctgata tgcagagata
     2281 aaaaatagga cagtggcgtg gtgaaaacac caggccggag cagaaggtta ttctggtggt
     2341 ttactttttc gtttcaggtg tcggataaac agccagataa acgtaaccac aggagccgag
     2401 ggtgtcggct tcacaggtca gccccttcgc atacagtgtc acggtatgct gatggcgggg
     2461 attcagttca ccactggtga gcattaattt cagttgtttc atcagcagcg gaaaggcctg
     2521 gtccagaggg tacgcatccg catctctgaa ccggcctctg ataccggcac ggtcggcaag
     2581 gtaatgcaac cggttaccct cctgcaccag acgggcgccg aaacagggcg tcactgtgca
     2641 gggtagtccc caccagggat ggtcgtcatt gtcatcggga tgcgttgtcc cggaaagtgt
     2701 gtctgacacg ataaaatcct cacagaaaat cggtgaatga tagtttaacg atgacgggtc
     2761 agccggcgcg cagaccggct tcggtaaagg tgtattcgtt gatgagcagg acctcatcca
     2821 cagcggcgtc tgagctctgc cagtcgtact cgttttccgg gtgacggaac atcagttcag
     2881 ggtgacgctc atcagccgga catacggacc aaaactgtcc ttacggcgtt ctgcaaacac
     2941 ggccagcaca ccgggaatat cctgcacttc acgaccggta tacgcttcag cactgccgtg
     3001 ccagcggtat ttgccggtac agaacggaaa aagacgggat gccggatgct gacggtgaat
     3061 acgcatggct tcgccacggg tgatgatttt catagtggga tacctctgaa gacagaagat
     3121 aaaagtgaaa acaggtgtga tgtggttgtg acgggttaaa gcagaccata ttcggcaaag
     3181 gagaaaacct ggctgccacc gactatcaga tggtccggca cccggatatc caccaggccc
     3241 agtgcctgta ccagacgttc cgtgataagg cggtctgcct tgctgggtgt gacttcaccg
     3301 gacgggtgat tgtgtgccag caccacagca gcggcattgt gatacagggc gcgtttaatc
     3361 acttcccggg gatggacttc cgtgcggttg atggtgccgg tgaagagggt ttcaccggca
     3421 atcagctgat tctggttgtt cagatacagc acccggaa
//
LOCUS       DAPGUL010000237         3445 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.242, whole genome shotgun sequence.
ACCESSION   DAPGUL010000237 DAPGUL010000000
VERSION     DAPGUL010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3445
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.242"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(398..1564)
                     /gene="ugd"
                     /locus_tag="RHX21_004730"
     CDS             complement(398..1564)
                     /gene="ugd"
                     /locus_tag="RHX21_004730"
                     /EC_number="1.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HDV1989783.1"
                     /translation="MKITISGTGYVGLSNGVLIAQNHEVVALDIVQAKVDMLNQKISP
                     IVDKEIQEYLAEKPLNFRATTDKHDAYRNADYVIIATPTDYDPKTNYFNTSTVEAVIR
                     DVTEINPNAVMIIKSTIPVGFTRDIKERLGIDNVIFSPEFLREGRALYDNLHPSRIVI
                     GERSARAERFADLLKEGAIKQDIPTLFTDSTEAEAIKLFANTYLALRVAYFNELDSYA
                     ESQGLNSKQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYESVPNNIIAAI
                     VDANRTRKDFIADSILARKPKVVGVYRLIMKSGSDNFRASSIQGIMKRIKAKGIPVII
                     YEPVMQEDEFFNSRVVRDLDAFKQEADVIISNRMAEELADVADKVYTRDLFGND"
     gene            complement(1728..3098)
                     /gene="rfbK1"
                     /locus_tag="RHX21_004731"
     CDS             complement(1728..3098)
                     /gene="rfbK1"
                     /locus_tag="RHX21_004731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032248255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O9 family phosphomannomutase RfbK1"
                     /protein_id="HDV1989784.1"
                     /translation="MTQLTCFKAYDIRGELGEELNEDIAYRIGRAYGEFLKPGKIVVG
                     GDVRLTSESLKLALARGLMDAGTDVLDIGLSGTEEIYFATFHLGVDGGIEVTASHNPM
                     NYNGMKLVRENAKPISGDTGLRDIQRLAEENQFPPVDPARRGTLSKISVLKEYVDHLM
                     SYVDFSNFTRPLKLVVNSGNGAAGHVIDEVEKRFAAAGVPVTFIKVHHQPDGHFPNGI
                     PNPLLPECRQDTADAVREHLADMGIAFDGDFDRCFLFDDEASFIEGYYIVGLLAEAFL
                     QKQPGAKIIHDPRLTWNTVDIVTRSGGQPVMSKTGHAFIKERMRQEDAIYGGEMSAHH
                     YFRDFAYCDSGMIPWLLVAELLCLKNSSLKSLVADRQAAFPASGEINRKLGNAAEAIA
                     RIRAQYEPAAAHIDTTDGISIEYPEWRFNLRTSNTEPVVRLNVESRADTGLMNAKTEE
                     ILALLK"
     gene            complement(3122..>3445)
                     /locus_tag="RHX21_004732"
     CDS             complement(3122..>3445)
                     /locus_tag="RHX21_004732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019725197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDV1989785.1"
                     /translation="PWGRCDVVVQTPRFNVNRITVKPGGAFSMQMHHHRAEHWVILAG
                     TGQVTVNGKQFLLSENQSTFIPIGAEHCLENPGCIPLEVLEIQSGSYLGEDDIIRIKD
                     QYGRC"
BASE COUNT          787 a          965 c          885 g          808 t
ORIGIN      
        1 taagaaaata ttaagagata aaaaaatgat atgacagaat gaccgttcat tctgcgtttt
       61 ggcgtggcct taaggcaaga aaaaataacg ttactcacgc cctgttcctc atatttcccc
      121 agggtataaa taataaaagc ctgcgttgca ggctttgttt tacctcccgg cgcttatctc
      181 cggcatctac atcacagtga cggtagctct tcacaaggta agtttaactt atcggacctg
      241 ttttcaacct gcaacggctt ttaagcagga tcgtaatgtc cattacaatt tattgaggtt
      301 aatctgaatg tgcgagaaat acgcacagtg aggaatatag cggggagata aagaagcata
      361 ctggcggcga ggagccgcca gtgtcagaca ggcaggatta atcgttacca aacagatcgc
      421 gggtgtatac cttgtccgcc acatccgcca gctcttccgc catacggtta gagataatca
      481 catccgcctc ttgtttgaag gcatccaggt cgcgcactac gcgggagtta aagaactcat
      541 cttcctgcat caccggttca tagataataa ccggaatacc ttttgccttg atgcgcttca
      601 taatgccctg aatagaagag gcacggaagt tgtccgaacc actcttcatg atcaggcgat
      661 acacacccac cactttcggc ttacgggcaa gaatagaatc cgcgataaag tctttacggg
      721 tacggttagc atctacgata gccgcgatga tattgttcgg gaccgattcg tagttcgcca
      781 gcaactgctt ggtatctttc ggcaggcagt agccgccata gccaaaggac gggttgttat
      841 agtggttgcc gatacgcgga tccaggcata ccccttcgat aatctgcttg ctgttcagcc
      901 cctggctttc agcatagctg tcaagctcgt tgaaataggc aacgcgcagc gccagatagg
      961 tgttcgcgaa cagtttgatc gcttccgctt cagtggagtc ggtaaacagg gtcgggatat
     1021 cctgcttaat cgcgccttct ttcaacaggt ctgcgaaacg ttcggcacgt gcagagcgct
     1081 caccaatgac aatgcgcgac gggtgcaggt tatcgtacag cgcacggcct tcacgcagga
     1141 actcaggaga gaaaataaca ttatcaatcc ctaaacgttc tttgatgtcg cgggtgaacc
     1201 ccaccgggat ggtcgattta atgatcatca ccgcgttcgg gttgatctct gtgacatcgc
     1261 gaataaccgc ttccaccgta gaggtgttga agtagttagt cttgggatcg taatcggtcg
     1321 gcgtggcaat gatcacgtag tcggcattgc ggtacgcgtc gtgcttatcc gtggtggcac
     1381 ggaaatttaa cggtttttct gccagatatt cctgaatttc tttatcgaca atcggagaga
     1441 tcttctggtt aagcatatcc actttggcct gtacgatatc cagggcaacc acttcgtggt
     1501 tttgcgcaat caggacaccg ttcgataaac caacataacc tgtaccggaa atagtaattt
     1561 tcatgagatt acactttaat cagttaactg gataatggcg gatagccacg aaattaaata
     1621 atactgtggg cggttttacg ctttgaccag tggtatgtca agaataagcc ataaggtcaa
     1681 taatacgatt aaaatctgac cctatggctt ccattatgga taatgcatta cttgagaaga
     1741 gctaaaatct cttcggtttt tgcattcatt aacccagtat ccgctctgga ctccacgttc
     1801 agacgcacca ccggctccgt gttggacgtg cgcaggttaa agcgccactc agggtattca
     1861 atactgatac cgtccgttgt gtcgatgtgg gcggccgccg gctcatactg cgcccggatg
     1921 cgcgcgatcg cctccgccgc attccccagc ttgcggttga tctcccccga cgccgggaac
     1981 gccgcctggc ggtccgccac cagcgatttc agcgagctgt tcttcaggca cagcagctcc
     2041 gccaccagca gccacgggat catcccgctg tcgcagtagg cgaagtcgcg gaagtaatgg
     2101 tgcgcgctca tctccccgcc gtagatggcg tcctcctggc gcatccgctc cttgatgaac
     2161 gcatgcccgg tcttcgacat caccggctgg ccgccgctgc gggtcacgat gtccaccgtg
     2221 ttccacgtca gacgcgggtc gtgaatgatt ttcgcccccg gctgcttctg caggaacgct
     2281 tccgccagca ggccgacaat gtagtacccc tcgataaacg aagcttcgtc atcgaacagg
     2341 aagcagcgat cgaagtcgcc gtcaaaggca atccccatgt cggccagatg ctcgcgcacc
     2401 gcgtcggcgg tatcctggcg gcactccggc agcagcggat tagggatacc gttagggaaa
     2461 tggccatccg gctggtgatg caccttgata aaggttaccg gcaccccggc cgccgcgaag
     2521 cgtttctcca cctcatcaat cacgtgcccc gcagccccgt ttccggagtt caccaccagc
     2581 ttcagtggac gggtgaagtt cgagaagtcc acgtagctca tcagatggtc aacatactcc
     2641 ttcagtaccg atatcttgct cagggtcccg cgacgcgccg ggtccactgg cgggaactgg
     2701 ttttcctccg ccaggcgctg gatatcccgc aggccggtgt cgccgctgat gggcttcgcg
     2761 ttctcgcgca ccagcttcat gccattgtag ttcatcgggt tatggctcgc cgtcacctcg
     2821 ataccgccgt ccaccccgag gtggaaagtg gcgaagtaaa tctcttccgt gccgctcagt
     2881 ccgatgtcca gcacatcggt accggcgtcc attaacccgc gggccagcgc cagcttcaac
     2941 gactcgcttg tgaggcgcac atcccccccc accactatct tcccgggttt cagaaattcg
     3001 ccgtaggcgc gcccgatacg gtaggcgatg tcctcgttca gttcctcacc cagttcacca
     3061 cggatgtcat aagccttaaa acaagttaac tgtgtcattc tgcatcttgt cccgaaaata
     3121 attagcaacg accatactgg tctttaatac gaataatgtc gtcctcgccg aggtacgacc
     3181 ccgactggat ctccagcact tccagcggaa tacagccagg gttttccagg cagtgctcgg
     3241 cgccaatcgg aataaaggtg gactggttct cggacaacag gaactgctta ccgttgaccg
     3301 tcacctgacc ggtgccggcg agaataaccc aatgctcggc gcgatggtgg tgcatctgca
     3361 tcgagaaggc accgccaggt ttcaccgtga tgcggttgac gttgaagcgc ggggtctgga
     3421 ccaccacgtc gcagcggccc caggg
//
LOCUS       DAPGUL010000238         3351 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.243, whole genome shotgun sequence.
ACCESSION   DAPGUL010000238 DAPGUL010000000
VERSION     DAPGUL010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3351
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.243"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..189
                     /locus_tag="RHX21_004733"
     CDS             <1..189
                     /locus_tag="RHX21_004733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000854262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989786.1"
                     /translation="IKKIEVEEDYEFCVSLDKGNGLHEVRTFKSEREALDAYRILTLY
                     GYTVTIEKKEGNDWLFKV"
     gene            431..637
                     /locus_tag="RHX21_004734"
     CDS             431..637
                     /locus_tag="RHX21_004734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001541980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HDV1989787.1"
                     /translation="MLCVDLYLQSCVEDGKEPDTPFKGVFNVRLDPELHRRVAEMAME
                     EDLSLNAFVNKALEKEVSNHRAGA"
     gene            1000..1503
                     /locus_tag="RHX21_004735"
     CDS             1000..1503
                     /locus_tag="RHX21_004735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000781816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989788.1"
                     /translation="MKMIAFRLSDDELKLAEHNAISSGFTSINTFARHNVLNVDVQPS
                     NIPVSNESSKAVKTCLYPHEIELVKRNAALHGMSMSREIAIRVRQSLLKNEVCLYPDE
                     VKELKKLSTAVDRVGRNIHFIIKGERFCTVNDPDFRKDVVEVIELCKQIDSKLETLTK
                     SVVNRFG"
     gene            1507..2736
                     /locus_tag="RHX21_004736"
     CDS             1507..2736
                     /locus_tag="RHX21_004736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDV1989789.1"
                     /translation="MGVYVEQEYRIKRAKGTGRDPKSPKLSGRHIHASKSAFNHKVRH
                     GTDKKAYTWTPTKEVTFKITGSGKTAAGIKNGIDYITRNGELEAYCYDGKGSEQTGKG
                     EDFNREFTSTLSKGNDYSRTYRGENIDHVKNMVFSPPPEAGVSREDALKATIEFLKET
                     YPNHAFVAVYHDDKEDHPHVHVNIKLRDEETGRRLRLTKSETRKFRNGFHRKLKGMGY
                     DVTATWKKDPERKREIERLQAENPKRLRNVYKVVDFGETSYQNKAGEKRTPFLTYETL
                     KGGKQVTIWGKDLKNHFESEKLQPGTLIKVKKLAPTLVRSPMFNDDGTVAGYRETHRN
                     NWQIENIALERNRERQVHERETRQPEESDVKKQLSRKHEQGHNIGFALEHGFTKDSEE
                     HKKLRIQQERNWKGLGF"
     gene            2813..3106
                     /locus_tag="RHX21_004737"
     CDS             2813..3106
                     /locus_tag="RHX21_004737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="HDV1989790.1"
                     /translation="MTEHDAICISALHQIFSDEEHLSEQQKDIILMYAYGYTLNEIAD
                     FKGLKPSTVRKYLDSVRAELGGVSLAGIRTLVLIRTNALLVSSLSRISERGNL"
     gene            3103..3318
                     /locus_tag="RHX21_004738"
     CDS             3103..3318
                     /locus_tag="RHX21_004738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="HDV1989791.1"
                     /translation="MKKYLLFALPFFVVGCSEEVKSVDWWGQHLTEAKQKQAECEKSG
                     SDSQNCKNVKQALFIQSQKDAPVPTFD"
BASE COUNT         1081 a          602 c          781 g          887 t
ORIGIN      
        1 attaaaaaga tagaagtaga agaagattat gagttttgtg tatcccttga taaaggtaat
       61 ggattacacg aagtcagaac atttaaaagt gagcgtgagg cgttggatgc ttatcgcatt
      121 ttgacccttt acggatacac agtaactata gaaaagaagg agggtaatga ctggctattc
      181 aaggtgtgat caggttgttc caccaacctg atcacgttat cgacaatcaa aactgaatga
      241 ggtttttaaa tgtcaacgcg gcagatcgta cagcttgctg attcccttgt caaaggctgg
      301 gaaaccagaa ttccggcaat gaaatttagt gaatgggatc aattccggtg gtggttaaac
      361 tacctgcaag ggtatgaaat gttttaaata aaaaaagggg ctttctgccc ctttgtattt
      421 tttgacaaaa atgctatgtg tagatctgta tttacagtct tgtgtggagg atggaaagga
      481 acctgatacc ccgtttaaag gcgtgtttaa cgtcaggctt gatccagaac tgcatcgtcg
      541 ggtagcagaa atggcgatgg aagaagactt atcgttgaat gcctttgtta ataaggctct
      601 ggaaaaagaa gtcagcaatc atcgcgcagg ggcttaatta cccttgtttt ttatgccctg
      661 taagggcatg ggaggcgctt tgcgccggaa gccccgcagc gcagcgagga cttaaaaagc
      721 gttacggctt cagccgtaac aattcccagc cctgccaggc ctgttttttc tttcacaaat
      781 ctatcagcta tacgtttgcc agatggtcga agacgaaaga acctttcagc aacgaaatct
      841 gggcatatgc agcgacgatt ttatagccag gcacagtgcc acatatggta caatcaatgc
      901 aggatagaca atcatggtca aaatgttaac attttatcca tgattgtcca aaaacgatgt
      961 ttttgcctgt gcctgccgca ggctctgttg gggtgagtta tgaagatgat agcgttcaga
     1021 cttagtgatg atgagttaaa acttgcagag cataacgcta tatcaagtgg gtttaccagc
     1081 atcaatacat ttgccaggca taatgtactt aatgttgatg ttcaaccatc aaatataccc
     1141 gtcagcaatg aatcatcaaa ggctgttaaa acctgtttat accctcatga aatagaactt
     1201 gttaaacgta atgcagccct tcacggcatg agcatgagca gagaaattgc tattcgtgtg
     1261 cgtcagtctt tgttaaagaa tgaagtctgt ctttaccctg atgaagttaa ggaacttaaa
     1321 aaattatcaa ctgctgtaga tcgtgttggt cgcaacattc attttatcat aaaaggtgaa
     1381 agattttgca cggttaacga tcctgatttc agaaaagacg ttgttgaagt gattgaacta
     1441 tgtaagcaaa ttgattcaaa acttgaaacg ttaaccaaga gtgttgttaa cagatttggg
     1501 tgatttatgg gtgtgtatgt agaacaggaa taccgtatta aacgcgctaa agggactggg
     1561 cgtgatccga aatctcctaa gttatcggga agacatatac atgccagtaa atcggctttt
     1621 aatcataaag tcagacatgg cacagacaag aaagcatata cctggacgcc aacaaaagaa
     1681 gtcactttta aaatcacagg ttcagggaaa actgccgcag gtatcaaaaa cggtattgat
     1741 tacattaccc gtaatggtga acttgaggct tactgttatg atggaaaagg ttccgagcaa
     1801 acagggaaag gagaagactt taacagggag tttacttcaa ctttatctaa aggaaatgat
     1861 tactccagaa catatcgtgg agaaaacatc gatcatgtga aaaacatggt cttttcacca
     1921 ccaccagaag ctggagtaag cagggaagac gctctgaaag ctacgataga atttcttaaa
     1981 gagacttatc caaaccatgc tttcgttgcc gtataccatg atgataaaga agatcatcct
     2041 catgtacatg ttaatattaa acttcgtgat gaagaaacag gaaggagatt aagacttact
     2101 aagtctgaaa ccaggaagtt cagaaacggt tttcatagaa aactgaaagg tatgggatat
     2161 gatgttaccg ctacatggaa aaaagatccc gaacgtaaac gggagattga gcgattacag
     2221 gctgaaaatc cgaaaagact ccggaatgtt tacaaggttg tggattttgg ggagacttca
     2281 tatcagaata aggcagggga aaaacgaaca cctttcctca cttatgaaac tttaaaaggt
     2341 ggaaagcagg ttacgatttg gggtaaagac ctgaaaaatc atttcgagtc tgaaaagctc
     2401 cagccaggaa cgcttatcaa agttaaaaaa ctggctccta cgcttgtacg tagcccgatg
     2461 tttaatgatg atggaactgt tgcaggctac agggaaacgc atcgcaataa ctggcagatt
     2521 gaaaatattg cccttgagcg gaacagagaa cgtcaggttc atgagcgtga aaccaggcag
     2581 ccggaagaga gcgacgttaa aaagcagcta tccagaaaac atgagcaagg tcacaatatc
     2641 gggtttgctc ttgaacacgg gtttacaaag gattcagaag aacataaaaa actaagaata
     2701 cagcaagaga ggaactggaa aggcctggga ttttaatttg atttcggcgc aggtgaacaa
     2761 agcggctact ttgctcacct gctaatcaca acaacctacg agggaggtta tcatgactga
     2821 gcatgatgct atctgcattt ctgcacttca tcaaattttt agtgatgaag aacatttgag
     2881 tgagcaacaa aaagacatta ttctgatgta cgcttatggc tataccctga atgaaattgc
     2941 tgatttcaaa ggactaaagc cttcaactgt cagaaaatat cttgattctg taagagctga
     3001 actgggaggt gtctcgttgg cagggatcag aacactggta ctcattcgga ctaatgccct
     3061 tctcgtgtca agtctttcca ggatcagtga gagggggaat ttatgaaaaa atatctgctt
     3121 tttgctttgc cgttcttcgt tgttggttgt agtgaagaag taaaaagtgt ggattggtgg
     3181 gggcagcatc ttacggaagc taaacaaaag caggcagagt gtgagaagtc tggctctgat
     3241 tctcagaact gtaagaatgt taaacaagca ttgtttattc agtctcagaa ggatgctcca
     3301 gtccctacat tcgattaact aatgtttaaa tcatactaaa gcgcccatat g
//
LOCUS       DAPGUL010000239         3252 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.244, whole genome shotgun sequence.
ACCESSION   DAPGUL010000239 DAPGUL010000000
VERSION     DAPGUL010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3252
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.244"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            494..829
                     /locus_tag="RHX21_004739"
     CDS             494..829
                     /locus_tag="RHX21_004739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004026069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDV1989792.1"
                     /translation="MPYTAKRYQTENGEVPYTDWMKKLRRKDQTAALKVDSRIARAMG
                     GNFGDHKFERDGVWELRVDYGPGYRVYYSIEDGEIILLLIGGNKKTQTADLDKAVSYL
                     QDFKKRSKK"
     gene            826..1176
                     /locus_tag="RHX21_004740"
     CDS             826..1176
                     /locus_tag="RHX21_004740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDV1989793.1"
                     /translation="MTATKNVKSQKNDYSASVDHNAAMIEELRADPDYANAYLANALE
                     EINEPGGLGGFLVALRQVIEARGGISEAARKSGLARQSIYRALSPNGNPTITTLAQLT
                     SVAGLQFTLSKSSH"
     gene            1815..2330
                     /locus_tag="RHX21_004741"
     CDS             1815..2330
                     /locus_tag="RHX21_004741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaJ domain-containing protein"
                     /protein_id="HDV1989794.1"
                     /translation="MNIQEALNVFGLSGELTEKDIKAAYRKAALKYHPDRNPLGAELM
                     KAVNAAFDVLMANIDKINQFQSTDEHARYNYGDDLEKVLNVLSGLSGLVFEVIGNWVW
                     ISGETITHKETLKEIGCKWAAKKKQWFYRPDEHKSYWNREEHTIEEIRAKYGTTGQRR
                     ATGWQRVETRV"
     gene            2435..2977
                     /locus_tag="RHX21_004742"
     CDS             2435..2977
                     /locus_tag="RHX21_004742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001401654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989795.1"
                     /translation="MNSFFEQYHPVFEVVCRILGNGWRVNKLDDCSSRIKLTSPQFKN
                     YSVHIRMEKDRFSVVGSVDSRSWRSPHHVCTLSRKRNPVDIAADIERKILVNASQEVL
                     QAIEYEKHQVEKKDEIMILKGMLSQLVQLESWYGALTGFKAENGLNGKVTEQGDSYDL
                     QIRGLSIDQLVKITGYLKQL"
     gene            2974..3225
                     /locus_tag="RHX21_004743"
     CDS             2974..3225
                     /locus_tag="RHX21_004743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001565860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989796.1"
                     /translation="MRKNKGDVTYFLEKEGDNYRLTKRIKARTNVKIGNKTTKITLYD
                     AVLNENELQHIDFTCAGLRKDDETPVKNLIKEFMLNETR"
BASE COUNT         1033 a          646 c          772 g          801 t
ORIGIN      
        1 taatatcaac atgatatatt cttttgccaa ttgatttatg tgaccacttc atttcaacga
       61 tacataaatc aacagatcca gcaatgcccc tccccaaagt gtcacagaga agccctgaat
      121 cgctctctgc cgcttcgttc gatacaacca tgaggaaaac catgcgaaat gaaaaaaatc
      181 gcttaaaacg cgatacagcg cgttttaggg ggtattcaca aaacacacgt tgccttgaag
      241 aaattttgat caagatttaa ctactatccg gatcatgact acagatcaca gcaacaaggc
      301 tgctaaaaag cgttgagagg cgttaaacgc tgttaagact agggctaagt acaatgaaac
      361 ggaaaaaatg ctcagaatgc gttacagaac cttccagaaa gctaggattt ctcactttaa
      421 agagacattt ttcttgatct gttgtcactt ataagagaca atgtacacag gttaagggaa
      481 tgagggcggc aagatgcctt acacggcgaa acgatatcag acagaaaacg gtgaggttcc
      541 gtacaccgac tggatgaaaa aattaagacg taaagaccag accgcagcgt taaaggtgga
      601 ttccagaatt gcccgcgcta tgggcggaaa ttttggagat cataaattcg aaagggacgg
      661 tgtatgggaa ttacgggttg attacggtcc tggttacagg gtttattatt caatcgaaga
      721 tggtgaaata attcttctgc tcattggagg gaataaaaaa actcagacag ccgatttaga
      781 taaagccgtt agttatctgc aagattttaa aaagaggtca aaaaaatgac agcaaccaaa
      841 aatgtgaagt cgcagaaaaa tgattattcg gcatccgttg atcacaatgc cgccatgatt
      901 gaagaattgc gcgcagatcc tgattatgca aacgcttatc ttgctaatgc cctggaagaa
      961 ataaacgagc ctggtggttt aggtggtttt cttgttgcgc tacgtcaggt aatcgaggcg
     1021 cgagggggga tttccgaagc tgccaggaaa tctggccttg cccgtcagag tatttaccgc
     1081 gcattatccc ccaacggtaa cccgaccatc acaacgcttg cacaacttac atcggtagcc
     1141 ggattacagt tcactctcag taaatccagc cactaatctc tccagttccc cctaagcggg
     1201 ggaatttcca tgccatcaaa accgcagtta tcccgcccga cgttcaccgg tatttaatcg
     1261 gcaaatcgta caattgcgta ctggcaatag tttaatggtg tgtattaata cacatttaaa
     1321 ggcgatgtgg atgcgtgtgt taatgctaat gtatgcatac attagcatta acatagagca
     1381 gattctggcg cgttgcgccc gtagttcgct gatgctcaca cgcgcagtac agcgccccgt
     1441 cctgttgcga cgcaccagga cggcgtaaac tcgcttgcgc tcgcgctaac tgcggcattc
     1501 tgcggcgcaa atcagcataa tcatggcctg ctggtcagtt aggctttgca gggtgaaggg
     1561 atggccctgt gcatcctggt acgttcgtca gcggctgcgc cgcgcttcgg ggcgatgtgg
     1621 ctcctgtgct gccctggtat tttcgttcgc cccttccatc cgcttacgcg gattaaaaaa
     1681 cgtgataaca atcacttatc gagtaaaaaa aacgggagaa tacttgcaaa tacgacttaa
     1741 aggtcgtatt attatttcat cgaaagggga atggcccctc tcacaatagc ccagcagggc
     1801 aggagattta aaaaatgaat atccaggaag cattaaacgt ttttggatta tccggcgaat
     1861 taactgaaaa agatatcaaa gcagcataca gaaaagccgc cttaaaatat catccagatc
     1921 gtaacccgtt aggggctgaa ctgatgaaag cggtaaatgc agcttttgat gtattgatgg
     1981 caaatattga taaaataaat cagttccaga gtactgatga acatgctcga tataattacg
     2041 gtgatgacct ggaaaaagta ttaaacgttc tttctggttt atctggtctg gtatttgaag
     2101 tgataggtaa ctgggtctgg attagtggag aaactattac acataaggaa actttaaaag
     2161 aaatcgggtg taaatgggcg gcaaagaaaa aacaatggtt ttatcgtcca gacgaacata
     2221 aaagttactg gaatcgtgaa gaacacacga tagaagaaat ccgcgcaaaa tacggtacaa
     2281 ccggacagcg cagggcgaca gggtggcaac gcgtggaaac cagagtctaa ccagaacggg
     2341 ggcgagaagc ccccgatatt atagccagcc cgtcttttgg ggcatcgaac ccaaaaagac
     2401 gggaacagga gccacgtagc aaaaagggaa acagatgaac tctttttttg aacaatatca
     2461 ccctgtcttt gaagttgtct gccgtatcct ggggaacggc tggcgcgtga acaaacttga
     2521 tgattgttcg tctcgtataa aactgacgtc accgcagttt aaaaattact ctgtgcatat
     2581 tcggatggaa aaagaccggt tttctgttgt ggggagtgtg gatagtcgct cctggcgtag
     2641 tccgcatcat gtttgcacgt tatccagaaa acggaatccc gttgatattg cagccgatat
     2701 cgagcgaaaa attctggtaa atgcttcgca ggaggtgtta caggcgattg agtatgagaa
     2761 acaccaggtg gaaaaaaagg acgaaattat gatcctgaaa ggtatgttat cgcaacttgt
     2821 ccagcttgaa agctggtatg gggcattgac aggctttaaa gctgaaaacg gattgaacgg
     2881 taaagtcacc gaacagggcg acagttatga tttacagatt cggggcttga gtatagatca
     2941 acttgttaaa attacagggt atttgaaaca gttatgagaa aaaataaagg tgatgtgact
     3001 tattttcttg aaaaagaagg tgacaattac aggcttacaa aaaggataaa agccagaaca
     3061 aatgttaaaa tcgggaacaa aactacgaaa atcacattgt atgatgccgt actgaatgag
     3121 aatgaattac aacatattga ttttacgtgt gccggattaa ggaaagacga tgagacgcca
     3181 gttaagaatt taattaagga gtttatgtta aatgaaaccc gataatacac ctgaaaatgt
     3241 aaaaaaatta cg
//
LOCUS       DAPGUL010000240         3158 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.245, whole genome shotgun sequence.
ACCESSION   DAPGUL010000240 DAPGUL010000000
VERSION     DAPGUL010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3158
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.245"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            120..1802
                     /locus_tag="RHX21_004744"
     CDS             120..1802
                     /locus_tag="RHX21_004744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416015.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase"
                     /protein_id="HDV1989797.1"
                     /translation="MKSALKKSVVSTSISLILASGMAAFAAHAADDVKLKATKTNVAF
                     SDFTPTEYSTKGKPNIIVLTMDDLGYGQLPFDKGSFDPKTMENREVVDTYKIGIDKAI
                     EAAQKSTPTLLSLMDEGVRFTNGYVAHGVSGPSRAAIMTGRAPARFGVYSNTDAQDGI
                     PLTETFLPELFQNHGYYTAAVGKWHLSKISNVPVPEDKQTRDYHDNFTTFSAEEWQPQ
                     NRGFDYFMGFHAAGTAYYNSPSLFKNRERVPAKGYISDQLTDEAIGVVDRAKTLDQPF
                     MLYLAYNAPHLPNDNPAPDQYQKQFNTGSQTADNYYASVYSVDQGVKRILEQLKKNGQ
                     YDNTIILFTSDNGAVIDGPLPLNGAQKGYKSQTYPGGTHTPMFMWWKGKLQPGNYDKL
                     ISAMDFYPTALDAADISIPKDLKLDGVSLLPWLQDKKQGEPHKNLTWITSYSHWFDEE
                     NIPFWDNYHKFVRHQSDDYPHNPNTEDLSQFSYTVRNNDYSLVYTVENNQLGLYKLTD
                     LQQKDNLAAANPQVVKEMQGVVREFIDSSQPPLSEVNQEKFNNIKKALSEAK"
     gene            1854..3011
                     /locus_tag="RHX21_004745"
     CDS             1854..3011
                     /locus_tag="RHX21_004745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416014.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase maturase"
                     /protein_id="HDV1989798.1"
                     /translation="MHVTAKPSSFQCNLKCDYCFYLEKESQFTHEKWMDDSTLKEFIK
                     QYIAASGNQVYFTWQGGEPTLAGLDFFRKVIHYQQRYAGQKRIFNALQTNGILLNNEW
                     CAFLKEHEFLVGISIDGPQELHDRYRRSNSGNGTFAKVIAAIERLKSYQVEFNTLTVI
                     NNVNVHYPLEVYHFLKSIGSKHMQFIELLETGTPNIDFSGHSENTFRIIDFSVPPTAY
                     GKFMSTIFMQWVKNDVGEIFIRQFESFVSRFLGNGHTSCIFQESCKDNLVVESNGDIY
                     ECDHFVYPQYKIGNINKSELKTMNSVQLTAQKKRISAKCQQCAYKPICNGGCPKHRIT
                     KVNNETVSYFCEGYKILFSTMVPYMNAMVELAKNRVPLYHIMDVAKQMENN"
     gene            complement(2977..3099)
                     /locus_tag="RHX21_004746"
     CDS             complement(2977..3099)
                     /locus_tag="RHX21_004746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989799.1"
                     /translation="MTKHPTGIYVGCLVKVIRRRLRMELKESVINYSPFVLQHP"
BASE COUNT          958 a          681 c          633 g          886 t
ORIGIN      
        1 ttatttccct ttttttagct aaatctgcta tctctttatg tgactaactt cacttacatc
       61 cacttatttc tcttcgtaaa attacttcgg aattaagtac aataagaaga ggaacattta
      121 tgaagtctgc attaaagaaa agtgtcgtaa gtacctcgat atctttgata ctggcatctg
      181 gtatggctgc atttgctgct catgcggcag atgatgtaaa gctgaaagca accaaaacaa
      241 acgttgcttt ctcagacttt acgccgactg aatacagtac caaaggaaag ccaaatatta
      301 tcgtactaac catggatgat cttggttatg gacaacttcc ttttgataag ggatcttttg
      361 acccaaaaac aatggaaaat cgtgaagttg tcgataccta caaaataggg atagataaag
      421 ccattgaagc tgcacaaaaa tcaacgccga cgctcctttc attaatggat gaaggcgtac
      481 ggtttactaa cggctatgtg gcacacggtg tttccggccc ctcccgtgcc gcaataatga
      541 ccggtcgagc tcccgcccgc tttggtgtct attccaatac cgatgctcag gatggtattc
      601 cgctaacaga aactttcttg cctgaattat tccagaatca tggttattac actgcagcag
      661 taggtaaatg gcacttgtca aaaatcagta atgtgccggt accggaagat aaacaaacgc
      721 gtgactatca tgacaacttc accacatttt ctgcggaaga atggcaacct caaaaccgtg
      781 gctttgatta ctttatggga ttccacgctg caggaacggc atattacaac tccccttcac
      841 tgttcaaaaa tcgtgaacgt gtccccgcaa aaggttatat cagcgatcag ttaaccgatg
      901 aggcaattgg cgttgttgat cgtgccaaaa cacttgacca gccatttatg ctttacctgg
      961 cttataatgc tccgcacctg ccaaatgata atcctgcacc ggatcaatat cagaagcaat
     1021 ttaataccgg tagtcaaaca gcagataact actacgcttc cgtttattct gttgatcagg
     1081 gtgtaaaacg cattctcgaa caactgaaga aaaacggaca gtatgacaat acaattattc
     1141 tctttacctc cgataatggt gcggttatcg atggtcctct gccgctgaac ggggcgcaaa
     1201 aaggctataa gagtcagacc tatcctggcg gtactcacac cccaatgttt atgtggtgga
     1261 aaggaaaact tcaacccggt aattatgaca agctgatttc cgcaatggat ttctacccga
     1321 cagctcttga tgcagccgat atcagcattc caaaagacct taagctggat ggcgtttcct
     1381 tgctgccctg gttgcaagat aagaaacaag gcgagccaca taaaaatctg acctggataa
     1441 cctcttattc tcactggttt gacgaggaaa atattccatt ctgggataat taccacaaat
     1501 ttgttcgcca tcagtcagac gattacccgc ataaccccaa cactgaggac ttaagccaat
     1561 tctcttatac ggtgagaaat aacgattatt cgcttgtcta tacagtagaa aacaatcagt
     1621 taggtctcta caaactgacg gatctacagc aaaaagataa ccttgccgcc gccaatccgc
     1681 aggtcgttaa agagatgcaa ggcgtggtaa gagagtttat cgacagcagc cagccaccgc
     1741 ttagcgaggt aaatcaggag aagtttaaca atatcaagaa agcactaagc gaagcgaaat
     1801 aactaaacct tcatgcggcg gaattttccg ccgccttatt gagcgagata gcgatgcacg
     1861 ttacagccaa gccctccagt tttcaatgta atctcaaatg tgattactgt ttttaccttg
     1921 aaaaagagtc gcagtttact catgaaaaat ggatggatga cagtactctg aaagagttca
     1981 tcaaacaata tatcgcagcg tctggcaatc aggtctattt tacctggcaa ggcggtgaac
     2041 ccactctggc tggcctggat tttttccgta aagttattca ctatcaacaa cgctatgcag
     2101 gccaaaaacg tatttttaat gcattacaaa cgaatggcat tttattgaat aatgaatggt
     2161 gtgcctttct caaagaacat gaatttctgg ttggtatctc gatcgatggc ccccaggagt
     2221 tacatgaccg ttacagacgc agtaattcag gtaacggtac ttttgcaaaa gtgatagcag
     2281 ccatcgagcg tctgaaatca tatcaagtag agtttaatac gttaaccgtc attaataacg
     2341 ttaatgtcca ttaccctctt gaggtttatc attttttaaa atctatcggc agtaaacata
     2401 tgcaatttat cgaattgcta gaaaccggga cgccgaatat tgatttcagt ggtcatagtg
     2461 agaacacatt ccgtatcatt gatttttctg tgcctcccac ggcttatggc aagtttatgt
     2521 caaccatttt tatgcaatgg gttaaaaacg atgtgggtga aattttcatt cgtcagtttg
     2581 aaagctttgt cagccgtttt ttggggaatg ggcatacaag ttgtattttc caggagtcct
     2641 gcaaggataa tctggttgtt gaaagtaatg gagacattta cgaatgcgac cattttgtct
     2701 atccacagta caaaattgga aacattaata aatctgaact caaaacgatg aacagtgtac
     2761 aactgacagc gcaaaaaaaa cggatttcag cgaaatgtca gcaatgtgca tataaaccta
     2821 tctgcaatgg cggttgtcct aagcatcgta ttactaaagt aaacaatgag actgtttctt
     2881 atttttgcga aggttataaa atcctttttt caaccatggt accttatatg aacgccatgg
     2941 tggagttagc taagaacaga gtaccgcttt accacattat ggatgttgca aaacaaatgg
     3001 agaataatta ataacgctct cttttaactc cattcttagc ctccttctta tgaccttaac
     3061 aaggcacccg acataaattc ctgtcgggtg tttcgtcatc atcatcttcc cttgcgaaaa
     3121 tcctggctta cgtggtatgc gtcagggcat tagcaata
//
LOCUS       DAPGUL010000241         3103 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.246, whole genome shotgun sequence.
ACCESSION   DAPGUL010000241 DAPGUL010000000
VERSION     DAPGUL010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3103
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.246"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            789..1355
                     /locus_tag="RHX21_004747"
     CDS             789..1355
                     /locus_tag="RHX21_004747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus-type Gp2 protein"
                     /protein_id="HDV1989800.1"
                     /translation="MPKSYTPNWFFTALLDNHINQMMARYSCLRALRMDFFYRKDTPD
                     FLQPDHRWLELQLRMLLEQVEQFENIVGFFWVIEWTADHGFHAHVVFWIDRQRVKKIY
                     PFVERITECWRSITHNSGSVHRCTYQPHYTYNINIPVRHNDPESIDNIRGALHYLAKE
                     EQKDGLCAYGCNEVPERPAAGRPRKPHF"
     gene            1602..2174
                     /locus_tag="RHX21_004748"
     CDS             1602..2174
                     /locus_tag="RHX21_004748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001521648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989801.1"
                     /translation="MNAIPYFDYSLAPFWPSYQNKVIGVLESALREQSGSRIRRILLR
                     LPCEYDRTFSSRKIWFGMDFIETVSALMNATPGRDLCWLLTHHPEKPEYHAVLCVRQE
                     YFDGPELDRLILDAWSNVLGFASPGEAKQYQKQITRDVVLDSRSPDCEERLKELIWAF
                     SDFARDRRGVHDPEARYLASNPWYPVAGQL"
     gene            2243..2476
                     /locus_tag="RHX21_004749"
     CDS             2243..2476
                     /locus_tag="RHX21_004749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
                     /protein_id="HDV1989802.1"
                     /translation="MLTTTSHDSVWLRADDPLIDMNYITSFTGMTDKWFYKLISEGHF
                     PKPIKLGRSSRWYKSEVEQWMQQRIEESRGAAA"
     gene            2790..3055
                     /locus_tag="RHX21_004750"
                     /pseudo
     CDS             2790..3055
                     /locus_tag="RHX21_004750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001366840.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
BASE COUNT          799 a          689 c          702 g          913 t
ORIGIN      
        1 taactcatat gatattcaga taagttattc tctactacgc tattgctgat atccatctgt
       61 tcctgttttc agtgaaataa taattgattt taatttatcc atcatgaact gtattggatt
      121 aacaatgatt gtttatctga agtgttttaa ccattctggt gagcctcaat tcttcagtcg
      181 tcactgatta actgaatgtt tattctttga taaggtatcc atgattctgt aacgattaac
      241 agagctggat aaacaacaga atcaacagag tgaattcctg attatgtttg tttcgggttg
      301 tattgtttaa gatgcagggt aaaaatcatg ccagtggtat tttttactct ggtaatgtgt
      361 gcggttaacg ttcatgtcct taagaacaga ttggatgagg gcgtataagt ttattgcgtt
      421 ggccttgtac acgttttttc agactcactg agagcaagtt tgtagtttat gatgttattg
      481 gtcgtaatat gtttcttaat ctcctggtag tgggttttta tcgcgtgttt tgcagtattt
      541 cgtgatgttt attgattctg tattttattc gctcctcgtt tatctcatct ctttagctaa
      601 taccatcaga taatccattt ctttctgcat aatgctgcgt atcgttaata actcgtcgta
      661 tccattctgc tacagcatgc ctgataaata ccatctgtaa gttattaccg ttttagatct
      721 gattatgagc gaaagcatta attcgctcac agagcttaaa acatcattaa ctttcaggag
      781 tcatcaacat gcctaaatct tacacaccaa actggttttt taccgcttta cttgacaatc
      841 acatcaatca aatgatggca cgttattcct gcctgcgggc cttacgaatg gatttcttct
      901 acaggaaaga tacgcctgat ttcttacaac ctgatcatcg ctggcttgaa ttgcagttgc
      961 gtatgctgct ggaacaggtt gaacaatttg aaaatattgt tggcttcttc tgggtgattg
     1021 aatggacggc tgatcatggt tttcatgcgc atgtggtttt ctggatcgat cgtcagaggg
     1081 ttaaaaaaat atatcccttt gtggagcgga ttacggaatg ctggcggtct attacgcata
     1141 acagcggttc ggtacatcgc tgtacatatc agccgcatta tacatacaac atcaacattc
     1201 ctgtgcgcca caacgatcct gaaagcatcg ataatattcg cggtgccctg cattatctgg
     1261 cgaaagaaga gcaaaaagac gggctgtgtg cctacggctg caatgaagtt cctgaacgtc
     1321 ctgctgcagg gcgtcctcgt aagcctcact tctgaagctt aaggcctgag cctccgctcc
     1381 tggaaacact ccgtcggtaa aaacttaccg ccttgattaa tgatgtgaac cgaagtcaac
     1441 ggagatcatt ccccctgaac ctgcatccag tgttctttcc cttatcttcc cgttctgctt
     1501 cagttcttca cttattccat caatctcatc cgcaagccat aacacgtcag ctcattcacg
     1561 ggcaggacgc attgtgggct gcgcataacg gaacatatct tatgaatgct attccttatt
     1621 tcgactatag cctggcaccc ttctggccat cttatcagaa caaagtcatc ggcgtccttg
     1681 agagtgcgct gcgtgagcag tccggctccc ggatacgacg gatcctgctt cgtctgccat
     1741 gtgaatatga ccgtaccttc agcagcagaa agatctggtt cggtatggac tttatcgaaa
     1801 ccgtcagtgc gctgatgaat gcaacacctg gacgagatct ctgctggctc ctgacccatc
     1861 atcctgaaaa acctgaatac cacgcggtgc tgtgcgtcag acaggagtat ttcgatggcc
     1921 ctgaactgga ccggttgata ctggatgcct ggagtaacgt actgggcttc gcgtcaccgg
     1981 gtgaagcaaa gcagtatcag aagcagatca cccgggatgt ggtgctggac agtcgttcac
     2041 cggactgcga agagagactc aaagagttga tatgggcgtt cagtgatttc gcccgcgatc
     2101 gtcgtggtgt gcacgatccg gaagcccgtt acctcgccag taatccctgg tatcccgtag
     2161 caggccagct ctgaaagctc ggttcagcat ctttccctgc attcgcctaa ccttcataaa
     2221 tctcactgag gacattctga ccatgttgac cacaacaagc cacgacagcg tatggctgcg
     2281 tgccgacgat cccctgatcg acatgaacta catcaccagt ttcactggca tgaccgataa
     2341 atggttttac aagctgatca gtgaaggcca tttccctaaa cccatcaaac tggggcgcag
     2401 cagccgctgg tacaaaagcg aagtggagca gtggatgcaa cagcgaatcg aggagtcacg
     2461 aggagcagca gcatgaaacg tgttgtaatg ccggtacgct ggcaatgtgc aaaatgccag
     2521 cgctggtatt gtggaacccg gccctgcccc tggtgctggc gacatttacg ttcatcttct
     2581 tgcagacatt ctccagtcag cctgcaggtt atagctattc ctgactgatt cgtcatttta
     2641 ttcttattga ttataactgg cattacaccg gtgccggagt gtttttctgt aagtctgcgc
     2701 cggttcagta aattagaaaa gaaacatttg tcagcgccag tgatataagg cgtaacggct
     2761 aacaatccag agcaagtcat attcatgatg tgacaatgaa aatgccaatg gggtatgaaa
     2821 cgttaatagg tgaactgggg gaaggtcttt ccggcggtca aaaacagcgt atattcattg
     2881 cccgagcttt ataccggaaa cctggaatat tatttatgga tgaggctaca agttctcttg
     2941 atacagaaag tgaacgtttc gtgaatgctg ccataaaaaa atgaatatca ctcgggtgat
     3001 tattgcacac agagaaacta cgttgagaac tgttgacagg attatttcta tttaaaatcc
     3061 actggtgtaa ctttgtaagg agttttgtct atgggggagg tta
//
LOCUS       DAPGUL010000242         3044 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.247, whole genome shotgun sequence.
ACCESSION   DAPGUL010000242 DAPGUL010000000
VERSION     DAPGUL010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3044)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3044)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3044
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.247"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(26..1885)
                     /gene="gss"
                     /locus_tag="RHX21_004751"
     CDS             complement(26..1885)
                     /gene="gss"
                     /locus_tag="RHX21_004751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutathionylspermidine
                     amidase/synthase"
                     /protein_id="HDV1989803.1"
                     /translation="MSKGTTSQDAPFGTLLGYAPGGVAIYSSDYSSLDPQEYEDDAVF
                     RSYIDDEYMGHKWQCVEFARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQ
                     AFPNGSPRAPVAGALLIWDKGGEFKDTGHVAIITQLHGNKVRIAEQNVIHSPLPQGQQ
                     WTRELEMVVENGCYTLKDTFDDTTILGWMIQTEDTEYSLPQPEIAGELLKISGARLEN
                     KGQFDGKWLDEKDPLQNAYVQANGQVINQDPYHYYTITESAEQELIKATNELHLMYLH
                     ATDKVLKDDNLLALFDIPKILWPRLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNAD
                     SASCHTEAGLILERWAEQGYKGNGFNPAEGLINELAGAWKHSRARPFVHIMQDKDIEE
                     NYHAQFMEQALHQAGFETRILRGLDELGWDAAGQLIDGEGRLVNCVWKTWAWETAFDQ
                     IREVSDREFAAVPIRTGHPQNEVRLIDVLLRPEVLVFEPLWTVIPGNKAILPILWSLF
                     PHHRYLLDTDFTVNDELVKTGYAVKPIAGRCGSNIDLVSHHEEVLDKTSGKFAEQKNI
                     YQQLWCLPKVDGKYIQVCTFTVGGNYGGTCLRGDESLVIKKESDIEPLIVVKK"
     gene            2090..2956
                     /gene="yghU"
                     /locus_tag="RHX21_004752"
     CDS             2090..2956
                     /gene="yghU"
                     /locus_tag="RHX21_004752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HDV1989804.1"
                     /translation="MTDNTYQPAKVWTWDKSAGGAFANINRPVSGPTHEKTLPVGKHP
                     LQLYSLGTPNGQKVTIMLEELLALGVTGAEYDAWLIRIGDGDQFSSGFVEVNPNSKIP
                     ALRDHTHNPPIRVFESGSILLYLAEKFGYFLPQDLAKRTETMNWLFWLQGAAPFLGGG
                     FGHFYHYAPMKIEYAINRFTMEAKRLLDVLDKQLAQHKFIAGDEYTIADMAIWPWFGN
                     VVLGGVYDAAEFLDAGSYKHVQRWAKEVGERPAVKRGRIVNRTNGPLNEQLHERHDAS
                     DFETNTEDKRQG"
BASE COUNT          712 a          821 c          778 g          733 t
ORIGIN      
        1 cagtacgggg ttgctacaac atgtattact ttttcaccac aattaacggt tcaatatcac
       61 tctctttttt gatgaccagt gattcatcac cgcgcaaaca cgtcccaccg tagttgccgc
      121 caacggtgaa ggtacatacc tgaatgtatt taccgtccac tttcggcaaa caccacagtt
      181 gctgatagat gtttttctgc tcggcaaatt taccgctggt tttgtccagc acctcttcat
      241 gatggctgac gaggtcgata ttgctgccac agcgaccggc gatcggtttc actgcgtaac
      301 ctgttttcac cagttcatca ttaacagtga aatcggtatc cagcaggtaa cgatggtgcg
      361 ggaacagcga ccagaggatc ggcagaatcg ctttgttgcc ggggatcacc gtccacagcg
      421 gctcaaagac cagcacttcc gggcgcagca atacgtcgat aagacgcact tcgttttgcg
      481 gatgaccggt acggattggc accgcagcaa actcacggtc gctaacttca cgaatctgat
      541 caaacgcggt ttcccacgcc caggttttcc acacgcagtt aaccagccgt ccttccccat
      601 caatcagttg cccggcagca tcccagccca gttcatccag cccgcgcaag atacgcgttt
      661 caaagcccgc ctggtgcagc gcctgctcca taaactgcgc gtgatagttt tcctcgatat
      721 ctttgtcctg catgatatgg acaaacggac gtgcacgact gtgtttccag gcaccagcca
      781 gttcgttaat cagcccttcc gccggattga agccgttgcc tttatagccc tgctccgccc
      841 aacgttcgag gatcaagccc gcttcggtat gacatgaggc agagtcggcg ttgtattcgt
      901 aaaccttcag gccacgctca tccatgcaga aatccatacg accagtgatc atatggtgac
      961 ggcgacgctg ccaggagaga cgcaaacgtg gccagaggat tttcgggatg tcgaacagcg
     1021 ccagcaggtt gtcatctttc agcaccttgt cggttgcgtg aagatacatc aggtgcagct
     1081 cgttggtggc tttaattagc tcctgctcgg cactctcggt aatggtgtag taatgataag
     1141 gatcctgatt gatcacctga ccgttggcct gcacataggc gttttgcagc ggatcttttt
     1201 catccagcca tttaccgtca aactggcctt tgttttccag gcgcgctccg ctgattttca
     1261 gcagctcgcc tgcaatttcc ggctgcggta agctgtattc agtatcttcc gtctggatca
     1321 tccagcccag aatggtggtg tcatcaaaag tgtctttcag ggtatagcag ccgttttcga
     1381 ccaccatctc cagctcacgc gtccactgtt gcccttgcgg caacggggaa tgaatcacgt
     1441 tctgttccgc aatacggact ttgttgccat gcaattgggt aatgatggcg acatggccag
     1501 tgtctttaaa ttcaccgcct ttatcccaga taagaagcgc acccgcgacc ggcgcacgcg
     1561 gcgagccgtt aggaaatgcc tgcaatggca ggatgttgtc attaaccact tctcgcagga
     1621 agcgcagcga gaaaatctcc cacgccatac ccacgtcagt aaagaccaca ccgtaattca
     1681 gaaagagaaa acggcgagca aattcaacgc attgccactt gtggcccata tattcgtcgt
     1741 cgatatagct acggaatacg gcgtcatctt cgtattcctg cggatcgaga gaactgtaat
     1801 ctgaagagta gattgctacc ccacctgggg cgtagcccaa taatgtcccg aacggggcat
     1861 cctggctggt cgttcctttg ctcatcactt tacctttaac aatacaacct aagcagttgg
     1921 cgtaattgtt gtgctctgat tacctgctca gcgacattaa ccggacagag gtcagactaa
     1981 tcatacacct catcgcagcg gctggcgcaa agggttaaaa aattcacatt ctgtacagca
     2041 agtgacctgc tacactgctt caacactacc actcagaagg caactcacta tgacagacaa
     2101 tacttatcag cccgcgaaag tctggacgtg ggataaatcc gctggcggcg cgttcgccaa
     2161 tatcaatcgc ccggtttctg gtccgacgca tgaaaaaacg ctgcccgttg gcaaacaccc
     2221 attgcaactt tattcgctgg gaacgccgaa cggtcagaaa gtaacgatta tgcttgagga
     2281 gctgctggcg ctgggcgtta ctggtgcaga gtacgacgcc tggctgattc gtattggcga
     2341 tggcgatcaa ttctccagcg gctttgtcga agtgaaccca aactcgaaga tcccggcgct
     2401 gcgcgatcat acgcataatc cgccgatccg cgtgtttgaa tctggttcga tcctgcttta
     2461 tctggcggag aaatttggct acttcctgcc gcaggatttg gcaaagcgta ctgaaacgat
     2521 gaactggctg ttctggttac agggcgcggc accgttcctc ggcggtggtt ttggtcactt
     2581 ttaccattac gcgccgatga aaattgagta cgccatcaac cgctttacca tggaagccaa
     2641 acgtctgctc gacgtgctgg ataagcaact ggcgcagcat aagtttattg cgggcgatga
     2701 gtacaccatt gcggatatgg cgatttggcc gtggtttggc aatgtggtgt taggcggcgt
     2761 gtatgatgcc gcagagtttc ttgatgcggg cagttataag catgtacaac gctgggcgaa
     2821 agaagtaggc gaacgtccgg cggtgaaacg tgggcgtatt gttaaccgca ccaacggacc
     2881 gctgaatgag cagttgcatg agcgccatga cgccagtgat ttcgagacga atacggaaga
     2941 taagcgtcag gggtaagggt tggtgttcgt cgcagcaagc catccaggcc ggataaggcg
     3001 ttcacgccgc atccggcaat cgtgcacaat gcctgatgcg acgc
//
LOCUS       DAPGUL010000243         3040 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.248, whole genome shotgun sequence.
ACCESSION   DAPGUL010000243 DAPGUL010000000
VERSION     DAPGUL010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3040)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3040)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3040
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.248"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..234
                     /locus_tag="RHX21_004753"
     CDS             <1..234
                     /locus_tag="RHX21_004753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDV1989805.1"
                     /translation="KTSMSRKGNCYDNAPMESFWGTLKNESLSHYRFNNRDEAISVIR
                     EYIEIFYNRQRRHSRLGNISPAAFREKYHQMAA"
     gene            388..2385
                     /gene="betT"
                     /locus_tag="RHX21_004754"
     CDS             388..2385
                     /gene="betT"
                     /locus_tag="RHX21_004754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004119118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline BCCT transporter BetT"
                     /protein_id="HDV1989806.1"
                     /translation="MSENDTIPKKSTSQINKAVFFTSALLIFLLVAFAAVFPDVADKN
                     FKLLQQQIFTNASWFYILAVALILLSVTFLGLSRYGDIKLGPDHAQPDFSYHSWFAML
                     FSAGMGIGLMFFGVAEPVMHYLSPPVGTPETVAAAKEAMRLTFFHWGLHAWAIYAIVA
                     LILAFFSYRHGLPLTLRSALYPIIGDRIYGPVGHAVDIFAVIGTVFGVATSLGYGVLQ
                     VNAGLNHLFGVPINETVQVILIVVITGLATISVVSGLDKGIRILSELNLGLALLLLAL
                     VLCLGPTVLLLKSFVENTGGYLSELVSKTFNLYAYEPKSSNWLGGWTLLYWGWWLSWS
                     PFVGMFIARVSRGRTIREFVTGVLFVPAGFTLMWMTVFGNSAIYLIMNQGATDLANTV
                     QQDVSLALFNFLEHFPFSSVLSFIAMAMVIVFFVTSADSGAMVVDTLASGGVANTPVW
                     QRIFWASLMGIVAIALLLAGGLSALQTVTIASALPFSVILLISIYGLLKALRRDLTKR
                     ESLSMATIAPTAARNPIPWQRRLRNIAYLPKRSLVKRFMDDVIQPAMTLVQEELNKQG
                     TISHISDAVDDRIRLEVDLGNELNFIYEVRLRGYISPTFALAAMDNDEQQTEQHRYYR
                     AEVYLKEGGQNYDVMGWNQEQLINDILDQYEKHLHFLHLVR"
     gene            2448..2861
                     /locus_tag="RHX21_004755"
     CDS             2448..2861
                     /locus_tag="RHX21_004755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000625671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2254 domain-containing protein"
                     /protein_id="HDV1989807.1"
                     /translation="MISRWKWMLKQTIKKLWFRATLFAIVAIITALLSILFKSMIPES
                     VSVKVGAEAVDNILNILASSMLAVTTFSLSIMVTAYGSATTNVTPRATRLVVEDVTTQ
                     NVLATFIGSFLLKWSTKTGHRVRVFPVSIFRFVWG"
     gene            complement(2796..>3040)
                     /locus_tag="RHX21_004756"
     CDS             complement(2796..>3040)
                     /locus_tag="RHX21_004756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDV1989808.1"
                     /translation="MSRRGNCWDNSPMERFFRSLKNEWMPVVGYVSFSEAAHAITDYI
                     VGYYSALRPHEYNGGLPPNESENRYWKNSNAVASFC"
BASE COUNT          706 a          725 c          763 g          846 t
ORIGIN      
        1 aaaacatcaa tgtcgcgtaa aggtaactgt tacgacaacg ctccgatgga aagcttctgg
       61 ggaacgctga aaaatgagag cctgagccac tatcgtttta ataaccggga tgaagccatc
      121 tcagtaatac gggaatacat tgagattttc tacaatcgtc agcgtcgtca ctctcgtctg
      181 gggaatatct ccccggcagc cttcagggaa aaatatcatc agatggctgc ttaaaaaaag
      241 aacaaatggt agtgtccgct attgccagta cacctcaaca ttccaccatg cattccgatt
      301 aacgccgcat agccagttga actttgctac tttgtgagag gtagtacctt ctatccagtg
      361 cgaatttaat taatggaata aatgattatg agtgaaaatg atacaatccc aaagaagtct
      421 acaagtcaga ttaacaaagc ggtattcttt acatctgctt tgctaatttt ccttcttgtc
      481 gcctttgccg ccgtattccc ggatgtcgcc gacaaaaatt ttaaactact tcagcaacaa
      541 atcttcacga atgccagctg gttctacatc cttgctgtgg ccctgatttt actgagtgtc
      601 acgttccttg gactctcacg ctacggtgat atcaagctgg gcccggacca tgcgcagcct
      661 gatttcagct accactcctg gtttgcgatg cttttttcgg cagggatggg gatcggcctg
      721 atgttctttg gcgttgccga acctgtaatg cattatcttt cgccacccgt tggcactcca
      781 gaaaccgttg cggcagccaa ggaagcaatg cgtctgacct ttttccactg gggactgcac
      841 gcatgggcaa tttatgccat tgtggcgctg attctggcgt tcttcagtta ccgtcacggt
      901 ctgcctttaa ctctgcgctc cgcactctat cccattattg gcgatcgcat atacggacct
      961 gtaggacatg cggttgatat tttcgctgtt ataggcacgg tctttggcgt tgcgacatca
     1021 ctgggttacg gtgttttgca ggtgaatgcc ggtttgaacc atcttttcgg ggtgcccatc
     1081 aatgaaacgg tgcaggtaat tctgatcgtg gtcatcacgg ggttagcgac gatttcagtg
     1141 gtgtccggtc tggataaggg aatacgtatc ctgtctgaac tcaatctggg tctggctttg
     1201 ttgctcctgg cgctggtcct gtgtctggga ccaaccgtgc ttctgctgaa gtcatttgtg
     1261 gaaaatacgg gcggttatct ttcggaactg gtgagtaaaa cgttcaacct ttacgcgtat
     1321 gagcccaagt cgagcaactg gctggggggc tggacattac tgtactgggg atggtggctt
     1381 tcatggtcgc cgtttgtggg gatgttcatc gcacgggtct cccgcgggcg aaccattcgc
     1441 gagtttgtca ccggcgtgct gtttgttccc gcgggtttta cgctaatgtg gatgacggtg
     1501 tttggtaaca gcgcgatcta tctcattatg aaccaggggg ccacagacct cgccaatact
     1561 gttcagcagg atgtgtcgct ggccctgttt aatttcctgg agcatttccc gttctcttct
     1621 gtgctgtcat tcattgcaat ggcgatggtc atcgtcttct ttgtaacgtc tgctgattcg
     1681 ggggcaatgg ttgtggatac tctggcatca ggtggagtgg caaacacacc cgtctggcag
     1741 cgaatattct gggcctcgct catgggcatt gttgcaattg cgcttctcct tgccggaggg
     1801 ctaagtgcgc tgcaaacggt gacaatagcg agtgcattgc ccttctcagt gatcttacta
     1861 atatccatat acggactttt aaaagctttg cgccgggatt tgaccaagcg tgaaagcctg
     1921 agcatggcga caattgctcc tacggctgca cgtaacccaa ttccttggca gagaaggtta
     1981 cgcaatatcg cgtatctgcc gaagcgatct cttgtgaaac gttttatgga cgacgttatc
     2041 cagcccgcca tgacgctggt tcaggaggaa ctgaacaagc aggggacgat aagccacatt
     2101 agtgatgcag tcgacgatcg tattcgtctt gaagtcgatt tgggcaacga gctgaatttt
     2161 atatatgaag tgaggcttcg cgggtatatc tcaccgacct tcgcgctcgc cgcaatggat
     2221 aatgatgagc agcagactga acaacatcga tattatcgcg ctgaggttta tctcaaagaa
     2281 ggcggtcaaa attatgatgt gatgggctgg aaccaggaac agctgattaa tgacatactg
     2341 gaccagtacg aaaaacacct gcacttcctg cacctggttc gttaatagca acatgccgtc
     2401 ctgggggcgg caattattat ctcggccgca atatgaggga atgcagaatg atttcacgct
     2461 ggaaatggat gctgaagcag acaattaaaa aactatggtt cagggcaacg ttattcgcaa
     2521 ttgtcgcgat aataacggcc cttttatcaa ttctttttaa atcaatgata cctgagtcgg
     2581 tttccgtgaa ggttggtgcg gaagcagtcg ataacattct gaacatactg gcatcgagta
     2641 tgctggcagt gaccacattt tcgctgagta tcatggtcac agcctacggt tcagccacta
     2701 ctaatgtgac tcccagagct acgcgtttag ttgttgaaga cgtcaccaca caaaatgtac
     2761 tggccacctt catcggttct tttctcttga agtggtcaac aaaaactggc caccgcgtta
     2821 gagtttttcc agtatcgatt ttccgattcg tttgggggta acccaccgtt atattcgtgc
     2881 ggtcttagtg cgctgtaata tccaacgata tagtccgtta tggcgtgagc tgcctcgctg
     2941 aagcttacgt aacccaccac cggcatccat tcgttcttca gactcctgaa gaagcgttcc
     3001 attgggctgt tatcccagca gtttccgcgc cggctcatac
//
LOCUS       DAPGUL010000244         3027 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.249, whole genome shotgun sequence.
ACCESSION   DAPGUL010000244 DAPGUL010000000
VERSION     DAPGUL010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3027
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.249"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            159..1370
                     /gene="bluF"
                     /locus_tag="RHX21_004757"
     CDS             159..1370
                     /gene="bluF"
                     /locus_tag="RHX21_004757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="blue light-responsive regulator BluF"
                     /protein_id="HDV1989809.1"
                     /translation="MLTTLIYRSHIRDDEPVKKIEEMVSIANRRNMQSDVTGILLFNG
                     SHFFQLLEGPEEQVKMIYRAICQDPRHYNIVELLCDYAPARRFGKAGMELFDLRLHER
                     DDVLQAVFDKGTSKFQLTYDDRALQFFRTFVLATEQSTYFEIPAEDSWLFIADGSDKE
                     LDSCALSPTINDHFAFHPIVDPLSRRIIAFEAIVQKNEDSPSAIAVGQRKDGEIYTAD
                     LKSKALAFTMAHALELGDKMISINLLPMTLVNEPDAVSFLLNEIKANALVPEQIIVEF
                     TESEVISRFDEFAEAIKSLKAAGISVAIDHFGAGFAGLLLLSRFQPDRIKISQELITN
                     VHKSGPRQAIIQAIIKCCTSLEIQVSAMGVATPEEWMWLESAGIEMFQGDLFAKAKLN
                     GIPSIAWPEKK"
     gene            1575..2306
                     /gene="bluR"
                     /locus_tag="RHX21_004758"
     CDS             1575..2306
                     /gene="bluR"
                     /locus_tag="RHX21_004758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor BluR"
                     /protein_id="HDV1989810.1"
                     /translation="MAYYSIGDVAERCGINPVTLRAWQRRYGLLKPQRSEGGHRLFDE
                     EDIQRIEEIKRWISNGVPVGKVKALLETTSQDTEDDWSRLQEEMMSILRMANPAKLRA
                     RIISLGREYPVDQLINHVYLPVRQRLVLDHNTSRIMSSMFDGALIEYAATSLFEMRRK
                     PGKEAILMAWNVEERARLWLEAWRLSLSGWHISVLADPIESPRPELFPTQTLIVWTGM
                     APTRRQNELLQHWGEQGYKVIFHAP"
     gene            2527..2931
                     /locus_tag="RHX21_004759"
     CDS             2527..2931
                     /locus_tag="RHX21_004759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1398 domain-containing protein"
                     /protein_id="HDV1989811.1"
                     /translation="MDQVVVFQKMFEQVRKEQNFSWFYSELKHHRIAHYIYYLATDNI
                     RIITHDDTVLLLRGTRNLLKVSTTKNPAKIKEAALLHICGKSTFREYCSTLAGAGVFR
                     WVTDVNHNKRSYYAIDNTLLYIEDVENNKPLI"
BASE COUNT          895 a          636 c          648 g          848 t
ORIGIN      
        1 ctgacaatct atacaagatt tttcgccaac tagtgttcaa ctttttccat tttttatcaa
       61 tgtaaagaaa cggttatgtt ttggtattaa aagaaagaca caagaagata tgtctgttac
      121 cgtcttactc tcgcctcacc cattaccctg gattgttaat gcttaccacc cttatttatc
      181 gtagccatat acgtgacgac gaacctgtca aaaaaatcga agaaatggtt tcgatagcaa
      241 atcgcaggaa catgcagtct gacgtaacag ggatcttact gtttaatggt tctcattttt
      301 tccagcttct ggaaggtccg gaagaacagg ttaaaatgat atatcgggct atatgccagg
      361 atccacggca ctataatatt gttgagctgc tgtgcgatta cgcgcctgct cgccgttttg
      421 gcaaagcggg aatggaatta tttgatttgc gcctgcacga gcgagatgac gttttacagg
      481 ccgtattcga caaaggcaca tcaaaatttc agctaactta tgatgacaga gcgctacaat
      541 tttttcgtac ttttgtcctt gcaaccgaac aatcaaccta tttcgagatc cctgccgaag
      601 actcctggct ttttatcgct gacggatctg ataaagaact tgattcctgt gccctttcac
      661 caactataaa cgaccacttt gcctttcatc ctattgtcga tcccttatcg cggcggataa
      721 tcgcttttga agccattgtg caaaaaaatg aagatagccc atcagccata gcggttgggc
      781 agcgtaaaga cggggaaatc tacacagcgg atctcaaaag taaggcgctt gcattcacga
      841 tggcacacgc acttgagctc ggtgataaaa tgatttcaat caatctatta cctatgaccc
      901 tggttaacga acctgacgca gtctcttttt tacttaatga aataaaggcc aatgctctgg
      961 tgcctgaaca aatcatcgtt gaatttactg aaagtgaagt catatctcgg tttgatgagt
     1021 ttgccgaagc gattaaatcg ctaaaggctg ctggtatcag tgtagcaatt gatcattttg
     1081 gcgcaggttt tgctggtttg ttactcctgt cacgcttcca gcctgacaga attaaaatca
     1141 gtcaggaatt gattaccaat gttcataaaa gtgggccacg gcaggcaatt attcaggcga
     1201 tcataaaatg ctgtacatca cttgaaattc aagtcagtgc tatgggcgtg gcaacaccag
     1261 aagagtggat gtggcttgaa tccgcaggaa ttgagatgtt tcagggagat ctgtttgcta
     1321 aagctaaatt gaatggtatc ccttccatag cgtggccaga gaaaaaataa ttttcagcac
     1381 attctttcac atgatttcag taaatcatcg tgaaaatgaa tacgttacgt ttaaatttaa
     1441 tccacattaa aaataatgtt tcatccaatt tagctgaaat cttatttata ctttgtacaa
     1501 ttttagcgta tattgtacaa agtattattg ggtcgtgtac aggcgacgga gatttgtgac
     1561 cgcaaggagg aattgtggct tattacagca ttggtgatgt tgctgaacgt tgcgggatta
     1621 atcctgtcac tctccgggcc tggcaacgcc gctacggttt gttaaaacca cagcgcagtg
     1681 aaggcggaca ccgactcttt gatgaagaag acatacaacg catcgaagag atcaagcgtt
     1741 ggataagtaa tggcgtccct gtaggcaaag ttaaagcatt actggaaacc accagccagg
     1801 atacggaaga tgactggagc cgcctgcaag aagagatgat gtcaattctt cgcatggcta
     1861 atcctgccaa actacgcgcg agaattattt cactgggtcg agagtaccca gtagatcaat
     1921 tgattaatca tgtttacctt cctgttcgcc agcgtctcgt gcttgatcac aacacctccc
     1981 gcattatgag cagtatgttt gacggcgcat taattgaata cgcagcaacc tcgcttttcg
     2041 aaatgcgccg taagcccggt aaagaagcca ttctgatggc gtggaatgtt gaagagagag
     2101 cacgattgtg gctggaagca tggcgtttat cattgtcagg atggcacatt tctgttcttg
     2161 ctgatcccat tgaatcgccg cgcccggaac tgttcccgac gcaaacattg attgtctgga
     2221 caggcatggc accaacgaga aggcaaaacg aacttttaca acattggggt gagcaaggtt
     2281 ataaagtcat ctttcatgcc ccctaatttc acctttatcc cgccccttag acagaatgtt
     2341 ataatctgaa cccacaacag cgtttgtacc ggagctggtc cgttgcaaaa tgctcaccgg
     2401 gagaattcag atattccctc tatcacactc tgtacatatc acagccaaag gacagaccag
     2461 attgaagtgg taaaaccgat cgtgcacact acgcagtctc acaactaaca agaggttatt
     2521 atcctgatgg atcaggtcgt tgtttttcaa aagatgtttg agcaagtgag aaaagagcaa
     2581 aacttctcct ggttttattc agaattaaaa catcaccgta ttgcacatta catttattat
     2641 ctggctacgg ataacatcag aattattact cacgatgaca cggttttgtt attaagagga
     2701 accaggaacc tgttaaaagt tagtacgacc aagaaccctg ctaaaataaa agaggccgca
     2761 ttgcttcata tttgcggaaa atctacattt cgggaatact gttcaacact agcaggcgcg
     2821 ggcgttttcc ggtgggttac tgatgttaat cataacaaac gcagttacta cgccattgat
     2881 aatacgcttt tatatattga agatgtagaa aataataaac cattaatcta gctaaagttg
     2941 gatgcttaag aaatgcttca taattcagta aggcattagc ataatgggaa taaaagtaca
     3001 gagactatcc ctatggatga taaatac
//
LOCUS       DAPGUL010000245         3009 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.250, whole genome shotgun sequence.
ACCESSION   DAPGUL010000245 DAPGUL010000000
VERSION     DAPGUL010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3009)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3009)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3009
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.250"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(191..409)
                     /locus_tag="RHX21_004760"
     CDS             complement(191..409)
                     /locus_tag="RHX21_004760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989812.1"
                     /translation="MNNSNNLDYFTLYIIFSIAFMLITLLVILIAKPSTGLGEVLVTI
                     NLLNALVWLAINLVNRLRERLVNHRDQQ"
     gene            complement(541..2064)
                     /locus_tag="RHX21_004761"
     CDS             complement(541..2064)
                     /locus_tag="RHX21_004761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415686.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HDV1989813.1"
                     /translation="MRNTLIPILVAICLFITGVAILNIQLWYSAKAEYLAGARYAANN
                     INHILEEASQATQTAVNIAGKECNLEEQYQLGTEAALKPHLRTIIILKQGIVWCTSLP
                     GNRVLLSRIPVFPDSNLLLAPAIDTVNRLPILLYQNQFADTRILVTISDQHIRGALNV
                     PLKGVRYVLRVADDIIGPTGDVMTLNGHYPYTEKVHSTKYHFTIIFNPPPLFSFYRLI
                     DKGFGILIFILLIACAAAFLLDRYFNKSATPEEILRRAINNGEIVPFYQPVVNGREGT
                     LRGVEVLARWKQPHGGYISPAAFIPLAEKSGLIVPLTQSLMNQVARQMNAIASKLPEG
                     FHIGINFSASHIISPTFVDECLNFRDSFTRRDLNLVLEVTEREPLNVDESLVQRLNIL
                     HENGFVIALDDFGTGYSGLSYLHDLHIDYIKIDHSFVGRVNADPESTRILDCVLDLAR
                     KLSISIVAEGVETKEQLDYLNQNNITFQQGYYFYKPVTYIDLVKIILSKPKVKVVVE"
     gene            complement(2396..2644)
                     /locus_tag="RHX21_004762"
     CDS             complement(2396..2644)
                     /locus_tag="RHX21_004762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989814.1"
                     /translation="MNNSIPERFIFQCALFKNLEREVFMTHGYVDSHIIDQALRLRLK
                     DETSVILSDLYLQILQYIEMHKTTLTDIIINDRESVLS"
     gene            complement(2757..2927)
                     /locus_tag="RHX21_004763"
     CDS             complement(2757..2927)
                     /locus_tag="RHX21_004763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001759935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component-system connector protein AriR"
                     /protein_id="HDV1989815.1"
                     /translation="MLGQAVTNLMLSGDNVNNKNIILSLIHSLETTSDILKADVIRKT
                     LEIVLRYTADDM"
BASE COUNT          934 a          635 c          602 g          838 t
ORIGIN      
        1 ttaacaaata actcttcgac atcaaaattg ttaatagttg cgatgaggat tatttcggtg
       61 atatataaaa acaaccgtga taacaccagg gttgacaact atttgcgcaa taatgccttt
      121 ccttcaatga tccaggcgtt cactgccagc aacccattca gccgcatact gacagtgaga
      181 aactgaaaga ttattgctga tccctgtggt tgacgagtct ttctcttaat cgattaacca
      241 gattgatcgc cagccaaaca agggcattaa gcaaatttat cgtcacaagc acttctccca
      301 gcccggtact gggttttgca ataaggatga ccaggagggt gatcagcata aatgcaatgg
      361 aaaagatgat atagagagtg aaataatcca gattattact attgttcatg ctactaatgg
      421 caatcctgtc aaaactttca aacaattata gcaaacaaaa taatgaacaa tagtaacaag
      481 aggcaacgag ctaattagct gtctataatt acaccgcact atggccttac tgatcaattt
      541 tcactcaacc acaaccttca ccttcggttt agaaaggata attttgacca ggtcgatgta
      601 tgtaacaggt ttatagaaat aataaccctg ctgaaatgtg atattatttt ggttcagata
      661 gtcaagttgt tctttcgttt cgacaccttc agcgacgata ctgatcgaaa gtttacgcgc
      721 cagatccaat acacaatcca gaattcgggt tgattctggg tctgcgttta cgcggccaac
      781 gaaactgtga tcaattttga tataatcaat atgcaggtca tgaagataag aaagccctga
      841 gtagccagta ccgaaatcat ccagcgcgat gacaaaacca ttttcatgca gaatgttcaa
      901 ccgctgaacc agactttcat caacattcaa tggctcacgc tcggtgactt ccagaacaag
      961 gtttaaatcg cggcgggtaa aactgtcacg gaaatttaaa cactcgtcga caaacgtcgg
     1021 cgaaataata tgcgaagcgc taaaattaat tccaatatga aaaccttccg gcaatttact
     1081 cgcgatagcg ttcatctgtc tggcaacctg attcatcagg ctttgcgtaa gcggaacgat
     1141 taatccggat ttttcagcaa gtggaataaa tgccgcgggt gatatatatc caccgtgagg
     1201 ttgtttccag cgggctaaca cctcaactcc ccgcaatgtc ccttcccgac catttaccac
     1261 aggttggtaa aaagggacga tctccccatt atttattgcc cgtcgcagga tctcttcagg
     1321 cgttgcgctt ttattgaaat atctatcaag caggaaggca gcggcgcagg cgattaacag
     1381 aataaatatt aaaatcccaa agcctttatc gataagtctg tagaagctaa agagtggcgg
     1441 cgggttaaag ataatagtga aatgatattt tgtggagtga accttctcgg tatagggata
     1501 atgtccatta agcgtcatca catcacccgt tggtccaata atgtcatccg ccacgcgtaa
     1561 tacatacctt acccctttca agggtacatt aagtgcccca cgaatatgct gatcgcttat
     1621 cgtaaccaaa atgcgcgtat ctgcaaattg gttctgatag agcaggatag gtaatctatt
     1681 aacggtgtcg attgctggag ccaacagtaa attactgtcc gggaaaacag gaatacgaga
     1741 caacaggacc cgattcccag gcagggatgt acaccagact attccctgtt tgagaatgat
     1801 gattgtgcgc aggtgaggtt tcagagctgc ttcagtgcca agctgatatt gctcctcgag
     1861 gttgcattcc ttcccggcaa tgttaaccgc tgtttgagtc gcttgtgacg cttcttcaag
     1921 tatatgattg atattgttgg cggcatatct cgctcccgcc aggtactctg cttttgcgga
     1981 ataccagagc tggatgttca aaatagcgac accggtaata aacaagcata tcgcaacgag
     2041 gatgggtatg agtgtattgc gcatttgctt gtcccggcca aagggtttaa tacatgaaaa
     2101 tgccattcat tcgctcgcgc tggcatctac agagagcatg gtagagagca taagaaatat
     2161 ccacgccgaa gataaaattt tctccatctt gatctaaccc attaattatt gagcataatg
     2221 taggcagtac aaaataagtt aggcgggata tcaggcgtca agaatggaga gcgagaactc
     2281 tccattcttg acacctgata ttgcggacat aataagaaag cataacgcct gaaatgctca
     2341 ctttgcatca gcatggtgat acagctgatg tttattctaa aaccttactc aagttctaag
     2401 agagcacgga ttccctgtca ttaataatga tatccgttag tgtagtctta tgcatttcaa
     2461 tgtactgcaa tatttgcaga tagagatcag aaagaatcac actggtttca tcttttaaac
     2521 gcaagcgtaa agcctgatca ataatatgac tatcaacata cccatgcgtc atgaacacct
     2581 ccctctcgag atttttaaac aaagcacatt gaaaaataaa tctctctggg attgaattat
     2641 tcatgtcagc ctcgtagaaa tattaaccca ataaaattat gctgtgtata gtctaaagcg
     2701 acagacaaaa ataagatgaa tgagttttct ataaacttat acttaataat tagaagttac
     2761 atatcatcag ctgtgtatcg caacacgatt tccagtgttt ttctaatcac atcagctttg
     2821 agaatatcac ttgttgtttc cagggagtgt atcagactta agataatatt tttattatta
     2881 acattatcgc ctgaaagcat taaattggtg acagcctgcc ctaacactgc tgactcttct
     2941 tctaacaaat tacccgaact gcgaaagtaa cttgctaacg ctttatcagt tattgcatta
     3001 tgaattgta
//
LOCUS       DAPGUL010000246         2933 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.251, whole genome shotgun sequence.
ACCESSION   DAPGUL010000246 DAPGUL010000000
VERSION     DAPGUL010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2933
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.251"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            210..1424
                     /locus_tag="RHX21_004764"
     CDS             210..1424
                     /locus_tag="RHX21_004764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4338 domain-containing protein"
                     /protein_id="HDV1989816.1"
                     /translation="MHKYPSIIVNINLREAKLKKKVREHLQSLGFTRSDSGALQAPGN
                     TKDVIRALHSSQRAERIFANQKFITLRAAKLIKFFASGNEVIPDKISPVLERVKSGTW
                     QGDLFRLAALTWSVPVSSGFGRRLRYLVWDESNGKLIGLIAIGDPVFNLAVRDNLIGW
                     DTHARSSRLVNLMDAYVLGALPPYNALLGGKLIACLLRSRDLYDDFAKVYGDTVGVIS
                     QKKKQARLLAITTTSSMGRSSVYNRLKLDGIQYLKSIGYTGGWGHFHIPDSLFIELRD
                     YLRDMDHAYADHYMFGNGPNWRLRTTKAALNALGFRDNLMKHGIQREVFISQLAENAT
                     SILQTGKGEPDLTSLLSAKEIAECAMARWMVPRSIRNPEYRLWKARDLFDFISNDSLN
                     FPPFDEIAKTVV"
     gene            2337..>2933
                     /locus_tag="RHX21_004765"
     CDS             2337..>2933
                     /locus_tag="RHX21_004765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989817.1"
                     /translation="MYAQGSSLLLSAVGVETSPAFFILNPGENDFVGVSGSIEQDVNL
                     FFSFYKKNVSVPRKYPSIDLVFTKRNKEKTIVSLHQRRCIEVMMEARMFGHKLEYMSM
                     PSGVEGVARIQRQTESNVIKLVSNDDIAAHDKSMRLLSPVALSQLSDCLANLTCHVEI
                     DFLGLGKIFLPGSSMLSLDDGKFIELSPNLRSRILSFIL"
BASE COUNT          873 a          530 c          630 g          900 t
ORIGIN      
        1 atttttttca tcaatactgt tgtaagctcc tgctatcaaa agttttgcac acaatctata
       61 agctcccaga attgcttgta taaatgctat cattggcgct gtcccgatcg agggagcaag
      121 gaggggactc tcttgtgcca tgcgattaat cactggggct ctaagtgaaa tttagtggga
      181 ctaaatacta attggaacgt gagataaaaa tgcacaaata tccctctata atagttaata
      241 tcaaccttcg agaagccaaa ctgaaaaaga aggtacgtga gcatttacaa tccttgggtt
      301 ttacaagatc tgattctgga gcgctccagg ccccgggaaa taccaaagat gtaatacggg
      361 ctcttcatag ttctcaacga gctgagcgga tatttgcaaa ccaaaagttc ataacgctaa
      421 gagcggcaaa gcttattaaa tttttcgcat ccggcaatga ggtcattccg gataagattt
      481 caccggtact tgaacgtgta aagtcaggaa cctggcaagg agatctcttt aggttagcag
      541 cattaacttg gtccgtacct gtttcaagcg gatttggaag gcgtctccgg tatcttgtat
      601 gggatgaaag caacggaaaa ttgatagggc tgatcgcaat tggtgaccct gtgttcaacc
      661 ttgcagtccg agataatttg attgggtggg atactcatgc cagaagttcc cggcttgtta
      721 atttgatgga tgcatacgtc ctcggtgctc ttccccctta taatgccctg ctgggaggaa
      781 aattaattgc atgtctgctt cgtagccgcg atctttatga tgactttgca aaggtctatg
      841 gtgataccgt tggagtaata tctcaaaaaa agaaacaagc acgtcttttg gctattacaa
      901 caacatcgtc tatggggcgc tcatcggtat ataaccgttt aaagctggat ggaattcaat
      961 atttaaaatc gattggatat acaggcggtt gggggcattt tcatatacct gatagcttgt
     1021 tcattgaatt acgtgattac ttacgtgata tggatcacgc ttatgcagat cattatatgt
     1081 ttggtaatgg gcctaactgg cgtttacgta caactaaggc agctttaaat gcactaggat
     1141 ttagagataa tttgatgaag catggaattc aacgtgaagt gtttatcagt cagctagcag
     1201 aaaatgcaac tagtattctg caaacaggca aaggtgaacc agatctaacc tctttgcttt
     1261 ctgctaaaga gatagctgag tgtgcgatgg cacgatggat ggttccacga tcaattcgca
     1321 atccagaata tcggctttgg aaagcaagag atctatttga ttttattagt aatgactcgc
     1381 taaactttcc cccgtttgac gagatagcga aaacagttgt ctaatcttaa ctgaaggggg
     1441 agtaagtgaa ttacgctatt gataagttca ccgggacact gatattagca gctcgagcaa
     1501 cgaaatatgc tcaatatgtt tgcccagttt gtaaaaaagg tgttaacctc cgtaaaggga
     1561 aggttatacc cccatatttt gctcatttgc ccggacatgg tacgtcagac tgtgaaaatt
     1621 ttgttcccgg aaattctatc attgtcgaaa ctattaaaac tatttcaaag cgatatatgg
     1681 atttgcgctt attgattcct gtcggaagta atagtcgaga gtggtcatta gaattagtgt
     1741 tgccaacctg taatttatgt agagcaaaga taacgttaga tgtaggaggc agaagccaaa
     1801 cgcttgatat gaggagtatg gtaaagagtc gccagattgg tgctgaatta tcagtaaaat
     1861 cttaccgtat tgtttcatat agtggtgaac cagatccaaa atttgtaaca gaagttgaaa
     1921 gagaatgccc aggtttacct tctgagggag cagcagtttt cactgcttta gggcgtgggg
     1981 catcgaaggg atttccacga gcacaagagt taagatgtac tgaaacattt gcctttcttt
     2041 ggcgacaccc tgttgctcca gattttcctg atgaattaga aataaaaagt ttagctagta
     2101 aacagggatg gaatttagct cttgttacaa ttcctgaagt cccttctgtg gagagtattt
     2161 catggctaaa atcttttaca taccttcctg ttgttcctgc cagaacatct attacagcaa
     2221 tttggccgtt cctaaatcaa aaaacaagta ttaatcatgt cgaatgtgtt tattctgaca
     2281 caatattgtt gtcaacaaat atggcaccaa catcatcaga aaatgttgga ccaactatgt
     2341 acgcacaagg ttcctcttta ttactttcag cggttggtgt tgaaacatca cctgctttct
     2401 tcattctaaa tcctggagaa aatgactttg tgggcgtttc tggctcaatt gagcaggacg
     2461 taaacttatt tttttctttc tataaaaaaa acgtttctgt acccagaaaa tatccctcaa
     2521 tagatttggt ttttactaag aggaataaag aaaagaccat cgtttcctta catcaaagaa
     2581 gatgcattga agttatgatg gaagcacgaa tgtttggcca taaattagaa tacatgtcta
     2641 tgccttctgg tgttgaagga gtggcaagaa ttcaaagaca aactgaaagt aatgttatta
     2701 agttagtttc taatgatgac attgcagctc atgataagag catgcggtta ctatctcctg
     2761 ttgcgttatc tcaattatct gattgcttag caaacttaac atgtcatgta gaaatagatt
     2821 ttttaggtct tggtaaaata tttttacctg gttcttctat gctatcatta gatgacggga
     2881 aatttattga attatctcct aatcttcgct cacggatatt aagttttata ctt
//
LOCUS       DAPGUL010000247         2924 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.252, whole genome shotgun sequence.
ACCESSION   DAPGUL010000247 DAPGUL010000000
VERSION     DAPGUL010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2924)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2924)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2924
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.252"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(114..190)
                     /locus_tag="RHX21_004766"
     tRNA            complement(114..190)
                     /locus_tag="RHX21_004766"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(154..156),aa:Asp,seq:gtc)
     gene            complement(323..1054)
                     /gene="dnaQ"
                     /locus_tag="RHX21_004767"
     CDS             complement(323..1054)
                     /gene="dnaQ"
                     /locus_tag="RHX21_004767"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706156.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="HDV1989818.1"
                     /translation="MSTAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVVNRRLT
                     GNNFHVYLKPDRLVDPEAFGVHGIADEFLLDKPTFAEVADEFMDYIRGAELVIHNAAF
                     DIGFMDYEFSLLKRDIPKTNTFCKVTDSLAVARKMFPGKRNSLDALCARYEIDNSKRT
                     LHGALLDAQILAEVYLAMTGGQTSMAFAMEGETQQQQGEATIQRIVRQASKLRVVFAT
                     DEELAAHEARLDLVEKKGGSCLWRA"
     gene            1119..1586
                     /gene="rnhA"
                     /locus_tag="RHX21_004768"
     CDS             1119..1586
                     /gene="rnhA"
                     /locus_tag="RHX21_004768"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI"
                     /protein_id="HDV1989819.1"
                     /translation="MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTN
                     NRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVD
                     LWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV"
     gene            complement(1583..2305)
                     /locus_tag="RHX21_004769"
     CDS             complement(1583..2305)
                     /locus_tag="RHX21_004769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308236.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDV1989820.1"
                     /translation="MKPARVPQTVVAPDRWGDLPWGELYRKALERQLNPWFTKMYGFH
                     LLKIGNLSAEINCEACAVSHQVNVSAQGMPVQVQADPLHLPFADKSVDVCLLAHTLPW
                     CTDPHRLLRETDRVLIDDGWLVISGFNPISLMGLRKLVPVLRKTSPYNSRMFTLMRQL
                     DWLSLLNFEVLHASRFHVLPWNKHGGKLLNAHIPALGCLQLIVARKRTIPLTLNPMKQ
                     SKNKPRIRQAVGATRQCRKPQA"
     gene            2339..>2924
                     /gene="gloB"
                     /locus_tag="RHX21_004770"
     CDS             2339..>2924
                     /gene="gloB"
                     /locus_tag="RHX21_004770"
                     /EC_number="3.1.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase"
                     /protein_id="HDV1989821.1"
                     /translation="MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAIAANNW
                     QPEAIFLTHHHHDHVGGVKELVEKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEF
                     SVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTASQMYQSLNKLSALPDDTL
                     VCCAHEYTLSNIKFALSILPHDLSINDYYRKVKEL"
BASE COUNT          785 a          710 c          688 g          741 t
ORIGIN      
        1 acatttacag cataacaaaa ccatagaccg aagaaatagc gggatttaaa tgcaaaaaaa
       61 accgcaaaat taaaaatctt gcggttctct gaactcattt tcatgagtga atttggcgga
      121 acggacggga ctcgaacccg cgaccccctg cgtgacaggc aggtattcta accgactgaa
      181 ctaccgctcc gcgttgtgtt ccgttgggaa cgaggcgaat attacggatt gcctcaccct
      241 tcgtcaacgg tttttctcat cttttgaatc gtttgctgca aaaatcgccc aagccgctat
      301 ttttagcgcc ttttacaggt atttatgccc gccagaggca gcttccgccc ttcttctcca
      361 ccagatcaag acgggcttca tgagctgcaa gctcttcatc tgtcgcaaaa acaacgcgta
      421 acttacttgc ctgacgtaca atgcgctgaa ttgttgcttc accttgttgc tgctgtgtct
      481 ctccttccat cgcaaaagcc atcgacgttt gaccaccggt catcgccaga taaacttccg
      541 caaggatctg tgcatcgagt aatgccccgt gtagcgttcg tttactgtta tctatttcgt
      601 agcgggcaca taacgcatcg aggctgttgc gcttaccagg aaacattttc ctcgccaccg
      661 caaggctatc ggtgacctta cagaaggtat tggtcttcgg aatatcgcgc ttaagcaacg
      721 aaaactcgta gtccataaag ccgatatcga acgctgcgtt atggatcacc aactccgcgc
      781 cgcggatata gtccatgaac tcatcggcta cttcggcaaa cgtgggctta tcgagcaaaa
      841 attcatcggc aataccatgt acgccaaagg cttccggatc caccagccga tcgggtttga
      901 gataaacatg gaagttattg cccgtcaggc gacggttcac cacttcaacg gcaccaatct
      961 caatgatctt gtggccttca tagtgcgcac caatctggtt cataccggtg gtttcggtat
     1021 cgagaacgat ctggcgtgta attgcagtgc tcatagcggt catttatgtc agacttgtcg
     1081 ttttacagtt cgattcaatt acaggaagtc taccagagat gcttaaacag gtagaaattt
     1141 tcaccgatgg ttcgtgtctg ggtaatcctg gacctggggg ttacggcgct attttacgct
     1201 atcgcggacg cgagaaaacc tttagcgcag gctacacccg caccaccaac aaccgtatgg
     1261 agttgatggc cgctattgtc gcgctggagg cgttaaaaga acattgcgaa gtcattttga
     1321 gtaccgacag ccagtatgtc cgccaaggta tcacccagtg gatccataac tggaaaaaac
     1381 gtggctggaa aacagcagac aaaaaaccag taaaaaatgt cgatctctgg caacgtcttg
     1441 atgctgcatt ggggcagcat caaatcaaat gggaatgggt taaaggccat gccggacacc
     1501 cggaaaacga acgctgtgat gaactggctc gtgctgcggc aatgaatccc acactggaag
     1561 atacgggcta ccaagtcgaa gtttaagctt gtggtttacg acattgccgg gtggctccaa
     1621 ccgcctggcg aattcgtggc ttgtttttac tctgtttcat cgggtttagc gttaaaggaa
     1681 tagtccgttt ccgggcaaca ataagttgta agcaaccaag cgcaggaata tgcgcattca
     1741 atagttttcc tccgtgtttg ttccacggga gaacgtggaa acggctggcg tgcagcactt
     1801 caaaattcaa caaagagagc cagtccagtt gccgcatcag agtaaacatc cggctgttat
     1861 agggcgaggt ttttcgcaat accggcacaa gtttgcgtaa tcccattaaa ctaatgggat
     1921 tgaagccact aatcaccagc cagccatcat caatcaatac ccgatcggtt tcacgcaata
     1981 aacgatgcgg atcggtgcac cacggcaatg tatgtgccag tagacaaaca tcaacggatt
     2041 tatcggcaaa aggaagatga agtggatccg cctgcacctg gacgggcatt ccttgcgcag
     2101 aaacattcac ttgatgagaa accgcgcacg cttcgcaatt gatttctgcg cttaaattgc
     2161 caatcttaag cagatgaaaa ccatacattt tagtgaacca cgggttgagc tggcgctcca
     2221 gcgccttgcg ataaagctct ccccagggca aatcgcccca gcgatcagga gccacgacag
     2281 tttgagggac tcttgccggt ttcatcacaa ccttccgttt cacactaaga ggtaatctat
     2341 gaatcttaac agtattcccg cctttgatga caattacatc tgggttttga atgatgaagc
     2401 aggtcgctgc ctgattgtcg atcccggaga cgcagagccg gtattaaacg ccattgccgc
     2461 caataactgg caaccggagg ccatatttct cacccaccat catcacgatc acgttggcgg
     2521 cgtaaaagaa ctggtggaaa agtttccgca aattgtggtg tatggtccac aagagacaca
     2581 agataaggga acaacacagg tagtcaaaga tggcgaaact gccttcgttt tggggcatga
     2641 atttagtgta attgccacac cgggtcacac tttaggacat atctgttact tcagtaaacc
     2701 ttatctattt tgcggcgaca cgctgttttc tggtgggtgt ggtaggttgt ttgaagggac
     2761 agcatcacaa atgtatcaat cacttaataa gttaagtgcg ttacctgacg atacattggt
     2821 atgttgtgct catgaatata cgttatcaaa tataaagttt gctttgagta ttcttccgca
     2881 cgatttgtcc ataaatgatt attatcgtaa agttaaggag ttac
//
LOCUS       DAPGUL010000248         2868 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.253, whole genome shotgun sequence.
ACCESSION   DAPGUL010000248 DAPGUL010000000
VERSION     DAPGUL010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2868)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2868)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2868
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.253"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            279..1445
                     /gene="nhaA"
                     /locus_tag="RHX21_004771"
     CDS             279..1445
                     /gene="nhaA"
                     /locus_tag="RHX21_004771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaA"
                     /protein_id="HDV1989822.1"
                     /translation="MKHLHRFFSSDASGGIILIIAAILAMIMANSGATSGWYHDFLET
                     PVQLRVGSLEINKNMLLWINDALMAVFFLLVGLEVKRELMQGSLASLRQAAFPVIAAI
                     GGMIVPALLYLAFNYADPITREGWAIPAATDIAFALGVLALLGSRVPLALKIFLMALA
                     IIDDLGAIIIIALFYTNDLSMASLGVAAVAIAVLAVLNLCGVRRTGVYILVGVVLWTA
                     VLKSGVHATLAGVIVGFFIPLKEKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSL
                     QGVTLDGLTSILPLGIIAGLLIGKPLGISLFCWLALRLKLAHLPEGTTYQQIMAVGIL
                     CGIGFTMSIFIASLAFGSVDPELINWAKLGILVGSISSAVIGYSWLRVRLRPSV"
     gene            1511..2410
                     /gene="nhaR"
                     /locus_tag="RHX21_004772"
     CDS             1511..2410
                     /gene="nhaR"
                     /locus_tag="RHX21_004772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705976.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional activator NhaR"
                     /protein_id="HDV1989823.1"
                     /translation="MSHINYNHLYYFWHVYKEGSVVGAAEALYLTPQTITGQIRALEE
                     RLQGKLFKRKGRGLEPSELGELVYRYADKMFTLSQEMLDIVNYRKESNLLFDVGVADA
                     LSKRLVSSVLNAAVVEGEPIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQEGL
                     FSVRIGECGVSFWCTNPPPEKPFPACLEERRLLIPGRRSMLGRKLLNWFNSQGLNVEI
                     LGEFDDAALMKAFGAMHNAIFVAPTLYAYDFYADKTVVEIGRVENVMEEYHAIFAERM
                     IQHPAVQRICNTDYSALFSPAAR"
     gene            complement(2449..>2868)
                     /locus_tag="RHX21_004773"
     CDS             complement(2449..>2868)
                     /locus_tag="RHX21_004773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000871680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial family protein"
                     /protein_id="HDV1989824.1"
                     /translation="CGFEDQSIDTGRFVLSRINNENYQFHHIRFDCIQGEQGELVFEP
                     SDVEYYFEPVTIQESGTSILKNELENSEDGAGQIGFQLSNDGTNEIQYGKSNYYSFQH
                     PHEGSNQIPLFIRPRTYGNNVSSGQIMSRVKIVVMYN"
BASE COUNT          686 a          637 c          713 g          832 t
ORIGIN      
        1 aaatattggc ctaacaaaca tcgccgactg acaacaaatt aattattact tttcctaatt
       61 aatctctcag aaatcctcac cttaagctat gattatctgg gcttagggtc actcgtgagc
      121 gcttacagcc gtcaaaaact catctcaccg ctgatggcgc aaattcttca atggatcgta
      181 aaaaacgagt tattcctaca ctataatctg attttaacga tgatttgtgc ggggtaaaat
      241 agtaaaaacg atctattcac ctgaaagaga aataaaaagt gaaacatctg catcgattct
      301 ttagcagtga tgcctcggga ggcattattc ttatcattgc cgctatcctg gcgatgatta
      361 tggccaatag cggcgcaacc agtggatggt atcacgactt tctggagacg ccggttcagc
      421 tccgggttgg ttcactcgaa atcaacaaaa acatgctgtt atggataaat gacgcgctga
      481 tggcggtatt tttcctgtta gtcggtctgg aagttaaacg tgaactgatg caaggatcgc
      541 tagccagctt acgccaggcc gcatttccag ttatcgccgc tattggtggg atgattgtgc
      601 cggcattact ctatctggcc tttaactatg ccgatccgat tacccgcgaa gggtgggcga
      661 tcccggcggc tactgacatt gcctttgcac ttggtgtgct ggcgctgttg ggaagtcgtg
      721 ttccgttagc gctgaagatc tttttgatgg ctctggctat tatcgacgat cttggggcca
      781 tcattatcat cgcattgttc tacactaatg acttatcgat ggcctctctt ggcgtcgcgg
      841 ctgtagcaat tgcggtactc gcggtattga atctgtgtgg tgtacgccgc acgggcgtct
      901 atattctggt tggcgtagtg ttgtggactg cggtgttgaa atcgggggtt cacgcaaccc
      961 tggcgggggt aattgtcggc ttctttattc ctttgaaaga gaagcatggg cgttctccag
     1021 cgaagcgact ggagcatgtg ttacacccgt gggtggcgta tctgattttg ccgctgtttg
     1081 catttgctaa tgctggcgtt tcactgcaag gtgtcacgct ggatggcttg acctccattc
     1141 tgccattggg gatcatcgct ggcttgctga ttggcaaacc gctggggatt agtctgttct
     1201 gctggttggc gctgcgtttg aaactggcgc atctgcctga gggaacgact tatcagcaaa
     1261 ttatggcggt ggggatcctg tgcggtatcg gttttactat gtctatcttt attgccagcc
     1321 tggcctttgg tagcgtagat ccagaactga ttaactgggc gaaactcggt atcctggtcg
     1381 gttctatctc ttcggcggta attggataca gctggttacg cgttcgtttg cgtccatcag
     1441 tttgacagga cggtttaccg gggagccata aacggctccc ttttcattgt tatcagggag
     1501 agaaatgagc atgtctcata tcaattacaa ccacttgtat tacttctggc atgtctataa
     1561 agaaggttcc gtggttggcg cagcggaggc gctttattta actccacaaa ccattaccgg
     1621 acagattcga gcgctggaag agcgcctgca aggcaaatta tttaaacgca agggacgtgg
     1681 tctcgaaccc agcgagctgg gagaactggt ctatcgctat gccgataaaa tgttcacctt
     1741 aagccaggaa atgctggata ttgtgaacta tcgcaaagaa tccaatttat tgtttgacgt
     1801 tggtgtggct gatgcacttt ccaaacgcct ggtcagtagc gtacttaacg ccgcagtggt
     1861 agaaggcgag cccattcatc ttcgctgctt cgaatccacc cacgaaatgc tgctggagca
     1921 attaagtcag cataaactgg atatgatcat ttctgactgt ccgatagact ctacgcagca
     1981 ggaaggcctg ttctccgtga gaattggcga atgtggcgtg agtttctggt gtacaaatcc
     2041 accaccagaa aaaccgttcc cggcttgtct ggaagaacgg cgacttttga ttcctgggcg
     2101 acgttcaatg ttagggcgca aattgcttaa ctggtttaac tcccagggat taaacgtaga
     2161 aatcctcggc gagtttgatg atgccgcgtt gatgaaagct tttggtgcga tgcacaatgc
     2221 aatcttcgtt gccccaacgc tttatgcata tgacttttat gccgataaaa ctgtcgtaga
     2281 aattggtcgc gtcgagaatg tgatggaaga gtaccatgct atttttgctg agcggatgat
     2341 tcagcacccg gcggtacagc gaatctgcaa tacggattat tctgcgcttt ttagtccagc
     2401 ggcgcgttaa tcggcacctc cccccaaagt taaggtgggg gagatagatt agttgtacat
     2461 aaccacgatt ttgactcggc tcattatttg cccgcttgag acattatttc catatgtacg
     2521 cgggcgaata aatagaggaa tctgattact tccttcatgg ggatgctgaa aagagtagta
     2581 attgctttta ccatactgga tttcattcgt accatcattg gagagttgaa agcctatttg
     2641 acccgcaccg tcctcactgt tttctaactc attttttaat atgctggttc ctgactcctg
     2701 tatcgtcact ggttcaaagt aatattcaac atcactgggt tcaaaaacta attcaccttg
     2761 ctcgccctgg atgcagtcaa atcttatatg atgaaactga taattttcat tattgatacg
     2821 agacagtaca aatcgtccag tgtcgatgga ttgatcttca aaaccaca
//
LOCUS       DAPGUL010000249         2848 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.254, whole genome shotgun sequence.
ACCESSION   DAPGUL010000249 DAPGUL010000000
VERSION     DAPGUL010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2848
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.254"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            54..686
                     /gene="comR"
                     /locus_tag="RHX21_004774"
     CDS             54..686
                     /gene="comR"
                     /locus_tag="RHX21_004774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415629.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family copper-responsive transcriptional
                     repressor ComR"
                     /protein_id="HDV1989825.1"
                     /translation="MATDSTQCVKKSRGRPKVFDRDAALDKAMKLFWQHGYEATSLAD
                     LVEATGAKAPTLYAEFTNKEGLFRAVLDRYIDRFAAKHEAQLFCEEKSVESALADYFA
                     AIANCFTSKDTPAGCFMINNCTTLSPDSGDIANTLKSRHAMQERTLQQFLCQRQARGE
                     IPTHCDVTHLAEFLNCIIQGMSISAREGASLEKLMQIAGTTLRLWPELVK"
     gene            complement(748..1287)
                     /locus_tag="RHX21_004775"
     CDS             complement(748..1287)
                     /locus_tag="RHX21_004775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HDV1989826.1"
                     /translation="MNKSMLAGIGIGVAAALGVAAVASLNVFERGPQYAQVVSATPIK
                     ETVKTPRQECRNVTVTHRRPVQDENRITGSVLGAVAGGVIGHQFGGGRGKDVATVVGA
                     LGGGYAGNQIQGSLQESDTYTTTQQRCKTVYDKSEKMLGYDVTYKIGDQQGKIRMDRD
                     PGTQIPLDSNGQLILNNKV"
     gene            complement(1514..2818)
                     /gene="ndh"
                     /locus_tag="RHX21_004776"
     CDS             complement(1514..2818)
                     /gene="ndh"
                     /locus_tag="RHX21_004776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017384716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone dehydrogenase"
                     /protein_id="HDV1989827.1"
                     /translation="MTTPLKKIVIVGGGAGGLEMATQLGHKLGRKKKAKITLVDRNHS
                     HLWKPLLHEVATGSLDEGVDALSYLAHARNHGFQFQLGSVIDIDREAKTITIAELRDE
                     KGELLVPERKIAYDTLVMALGSTSNDFNTPGVKENCIFLDNPHQARRFHQEMLNLFLK
                     YSANLGANGKVNIAIVGGGATGVELSAELHNAVKQLHSYGYKGLTNEALNVTLVEAGE
                     RILPALPPRISAAAHNELTKLGVRVLTQTMVTSADEGGLHTKDGEYIEADLMVWAAGI
                     KAPDFLKDIGGLETNRINQLVVEPTLQTTRDPDIYAIGDCASCPRPEGGFVPPRAQAA
                     HQMATCAMNNILAQMNGKPLKNYQYKDHGSLVSLSNFSTVGSLMGNLTRGSMMIEGRI
                     ARFVYISLYRMHQIALHGYFKTGLMMLVGSINRVIRPRLKLH"
BASE COUNT          684 a          782 c          694 g          688 t
ORIGIN      
        1 gtgattattt ttataataac ctttcattca cagtcaccag gtacaacggc atcatggcaa
       61 ctgactcaac acaatgtgta aaaaaaagcc gtggccgccc aaaagtgttc gacagggatg
      121 ccgcgcttga taaggccatg aaattgttct ggcaacacgg ttatgaagcg acttctcttg
      181 cggacctcgt cgaagcgacc ggagccaaag cgcccacgct atacgcggaa tttaccaaca
      241 aagaggggtt atttcgtgcc gttctcgacc gctatatcga tcgttttgcc gctaagcatg
      301 aagcacagct gttttgtgaa gagaaaagcg tggagtctgc gctggctgac tattttgctg
      361 ccatcgccaa ctgctttacc agcaaagaca ccccggcagg ctgcttcatg atcaacaact
      421 gcaccaccct ctccccagat tcaggagata tcgccaatac gttgaaatca cgccatgcga
      481 tgcaagagcg cactttgcag cagtttttat gtcaacgaca agcgcgcggg gaaatcccga
      541 cccactgtga cgtgacacat ctggcagaat tccttaattg tattattcag gggatgtcga
      601 tcagcgcacg cgaaggtgca tcgctggaaa aactaatgca gattgccgga acgactttgc
      661 gtttatggcc cgaactggtg aaataagtcg caaaaaaagc ccctcagcct gagcgaatga
      721 ggggccaaat tgcagagtac agccttgtta tactttgtta ttcaaaatca gttgcccatt
      781 actatctagc gggatctgcg tacccggatc gcggtccatg cggattttgc cctgctgatc
      841 gccaatctta taggtcacat cataaccgag cattttttct gacttgtcat acaccgtttt
      901 acaacgctgt tgcgtagtcg tgtaagtatc gctttcctgg agagagccct ggatctggtt
      961 accggcatat ccaccaccca gcgcccccac aacagtggcg acatctttac cacgaccacc
     1021 accaaactga tgccctatca cgccgccagc aacagcgccg agcaccgacc cggtaatgcg
     1081 attttcatcc tgcaccggtc gacgatgggt cactgtgacg ttgcgacact cctgacgcgg
     1141 tgttttaacc gtttccttga ttggggttgc agaaacaacc tgagcgtatt gcgggccccg
     1201 ttcaaacacg ttcagactgg ccactgccgc tacgcccagc gcagctgcga caccaatccc
     1261 gatacccgcc aacattgatt tattcacggg aacacctcct tctttgcagt tatgccaatc
     1321 atgcaagcga aggagaaaag cagctatcag acagaagatg aaaagcgcgg gaatggctgg
     1381 aaatacttaa ggattcggag gagtctgaag gaatgcctga tgcgacgctt aacgcgtctt
     1441 atcaggccta ccgctcgtac catttgtcca gggcggatga ggcgtttatg ccacatccgc
     1501 cagtgtacgt cgattaatgc aacttcaaac gcggacggat aacgcggtta atactcccca
     1561 ccagcatcat taatccggtt ttaaagtaac catgcagcgc aatctgatgc attcggtata
     1621 gcgagatata tacaaagcgc gcaattcgtc cttcaatcat cattgagccg cgcgtcaggt
     1681 tacccatcag gctaccgacg gtggagaagt tcgacagcga taccagcgaa ccatgatctt
     1741 tatactgata atttttcagc ggcttaccgt tcatctgcgc cagtatgttg ttcattgcgc
     1801 aagtcgccat ctggtgtgca gcctgagcac gcggcggaac aaagccccct tccggacgcg
     1861 ggcatgacgc gcagtcgcca atagcgtaaa tgtctggatc gcgggtggtt tgcagcgtcg
     1921 gttccaccac cagctggttg atacggttag tttcaagacc accgatatct ttcaggaagt
     1981 ctggcgcttt gatcccggct gcccacacca tcagatcagc ctcaatatat tcgccatctt
     2041 tagtgtgcag gccgccttca tcagcactgg tgaccatggt ttgcgtcagc acgcgaacgc
     2101 caagtttcgt tagctcgttg tgggccgcag cagagatacg tggcggtaat gcaggcaaaa
     2161 tacgttctcc cgcttctacc agcgttacgt tcagggcttc gttggtcagg cctttgtaac
     2221 cgtagctgtg cagttgcttg accgcgttgt gcaattcagc ggagagttct acacccgtcg
     2281 cgccgccgcc gacaatcgca atgttcactt tgccatttgc gcccaggttg gcggagtatt
     2341 tcaggaagag attcagcatc tcctggtgaa agcgacgcgc ctggtgcggg ttatcgagga
     2401 aaatgcagtt ctctttgaca cctggcgtat tgaaatcgtt agaggtgcta cccagcgcca
     2461 ttaccagggt gtcataggcg attttacgtt ccggaaccag cagttcacct ttctcatcgc
     2521 gcagttctgc aatagtgatt gttttcgctt cacgatcaat atcaatgacg gaacccagct
     2581 ggaactggaa accatgattg cgcgcatggg ccagatagct caacgcatcg acgccttcat
     2641 caagcgagcc agtcgccact tcgtgcagca gcggtttcca caggtggctg tggttacgat
     2701 cgaccagcgt aattttggct tttttcttac gtcccagctt atgccccagc tgtgttgcca
     2761 tttccagccc accagcaccg ccgccgacaa tcacaatctt tttcaatggc gtagtcaacg
     2821 tgaccccctt aaatttatta accaattg
//
LOCUS       DAPGUL010000250         2820 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.255, whole genome shotgun sequence.
ACCESSION   DAPGUL010000250 DAPGUL010000000
VERSION     DAPGUL010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2820
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.255"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(96..461)
                     /locus_tag="RHX21_004777"
                     /pseudo
     CDS             complement(96..461)
                     /locus_tag="RHX21_004777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275822.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1195..1574
                     /locus_tag="RHX21_004778"
                     /pseudo
     CDS             1195..1574
                     /locus_tag="RHX21_004778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000312579.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cobalamin biosynthesis protein CobW"
     gene            complement(1770..2072)
                     /locus_tag="RHX21_004779"
     CDS             complement(1770..2072)
                     /locus_tag="RHX21_004779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001468457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDV1989828.1"
                     /translation="MVFLTAGHLIPDRYVLVDAHQQPVDFTQGEYGLLLALAQNSRRV
                     LICEQLLDLIHGETTEVFDRTIDVLIMRLCRKIEINPHWCFASPIQRLASFWSNLS"
     gene            2370..2711
                     /locus_tag="RHX21_004780"
     CDS             2370..2711
                     /locus_tag="RHX21_004780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989829.1"
                     /translation="MNLKNIILSTVLSIASCHALAVGNSQIALSNLHVENTPSGTKAI
                     VGYAENKSNSVVKNAYVKFNLLKDGVVIGQTIDTASNLEPGQKWKIQAFINTFNGSPD
                     SFKVTEVKIVN"
BASE COUNT          865 a          632 c          586 g          737 t
ORIGIN      
        1 tatcttctca gtgaggacgt gaacgcctgt ctgaaattat gtgaatacaa cctccccaga
       61 atacaaacag gcaggggcac tggagtaacc gagcacaata cttctgcctt tttatatttt
      121 accgataatc tccgtttaat atagttctta ccgatttcat aatcggggtt ccatgtagat
      181 aaattatgaa cacctattgc tactgcactc gccactccca gaattacggt tggtgaccat
      241 aaagaaccag ctaaagctgt actcctgtac tcagtatata cacgacaact taatttcgtt
      301 ttctctattt catgctccac tctttttacc gtttcactaa catcggaaac attttcgatc
      361 acaaaactct tacgttcata aataagcctg cttaatgtat ttatatctaa aaatttcgca
      421 tcaaaagaat caatctgtac tgttttttct tgtgctgaca tcttcttttc ctggctggta
      481 tggcaagtga cggagacaag agaaacgttt taagctcagt tatctccgcc atcactttcc
      541 acgaatgaca agtaattttg cctattttaa aaccatgcaa aaggcagggt aaaaggagaa
      601 aattcgatcg aatcgatcga caaaatcgat catacatgat gaagattttt tatcgaatcc
      661 ataaaaatag tgacagctaa ccggcgttgc aggaacagtc agaaatgggc gtttgggaaa
      721 gagccatagc actacgtcgt cgctgacata gaggaactgt gctttgttga taagatcctt
      781 tatacggcaa ccaatccact ggacaaaaga tgaactacgt aatcaccggg ttctcactga
      841 cgaaatacag aagttaatga cacaactgtg ccatgtacct tgtacaacag cggtggaaag
      901 ctctcagaac aatggaattg cagaaaggtg ttaaaacgat gaaagccttc atacccaaat
      961 cgaatgtaag aacggcagta aagactgaat tgcgtaacct tgcagtagct cgagtattac
     1021 actgcatagt gtgcagggtt atctcccatc gagaaaatat cggcgccagc gaataacgtc
     1081 accttagatg tagcagttgc caaatagtga ctcaagggcg ggcttaccgc atacactgac
     1141 acttagcgga tcgacagaat attattagca gatcatcact gaacgctacg taattatcgt
     1201 aataaaggct ttttctggct accaggaaga cctgacatgg ctctgctctg gaaccaggcc
     1261 gcaggaagca tcaatctgga gtttatcagc tactggaatt ccggtgtatt ggcagcccct
     1321 gataatcacc tgaccctcga agagcgctct gctttgcaga aactctgggg cggtttggag
     1381 acaggagatg ccatttaacg attataggac gttctgatga agtccatgat tttacctccg
     1441 ccttaattaa ctgttttctt tctgaagaaa aaattgtctg gtggcaatca ggtggcattt
     1501 tcccggatcc ctggcccgct aatatatccc ggctgaacag acgattaacg agatattgca
     1561 aatatggcat ctgaatcgat tatgatttgg cggcatccat ctccgttcac agtttggcat
     1621 gcttccgatc attgattggc atccagccag tcactccggg aattaactct tttcaccgca
     1681 gtctccattg ccgtgtttaa accaatggag acgtcaatgt ccaaaaagag aatatccagg
     1741 agcactatgg atacctgttt taagatcctt cagctcaagt tcgaccagaa gctggctaac
     1801 cgttgtatcg gacttgcaaa acaccaatgg ggattgatct ctattttgcg acacagacgc
     1861 attatcaata catcgatggt gcgatcaaat acctcagtgg tctcaccgtg gatcaaatcc
     1921 agcaattgct cacagattaa gactcgtcgg gagttttgag ccaacgccag cagtaaccca
     1981 tattcacctt gagtgaaatc tacaggctgt tgatgagcat caaccagcac gtaacggtcc
     2041 gggatcaagt gtccagccgt taaaaaaacc actctactac cctgctcgac ctaagcctcg
     2101 gcgttcagcc gcctgaacgg gtatggcaag ggtgaaaaga aacagcatcc ccacagtacc
     2161 gaccagacga caggatgatg ctggaacaga aagcattcgc acctccctta gaattagaca
     2221 gtgcgtacag gatacgtaag acagggtgac ggggcggcga taaactctat ttacaaagct
     2281 gaaaattttc tgaagatgaa aaactattca acaaggttat ctgaggcgtt aaaataacca
     2341 gctcgattaa cgactaactt gaggtgaata tgaatttaaa aaatataatt ttaagtactg
     2401 ttttatcaat cgctagttgt catgccctgg ctgtaggtaa ttctcaaata gcgctatcta
     2461 accttcatgt ggaaaacacc ccaagtggga cgaaggcaat tgtgggttat gctgaaaata
     2521 aatcaaactc tgttgtcaaa aatgcttatg taaaatttaa tcttttaaaa gatggagtag
     2581 ttatcggtca aacaatcgac acagcatcca atcttgaacc aggccagaag tggaaaatac
     2641 aagccttcat taacaccttt aacggcagcc ccgactcatt caaagttact gaagtgaaaa
     2701 tagttaactg agtgcgccac tgactgccgc tacaaaaatt atatggaggt cctgggaaag
     2761 ggcagctctg caccaggccg ccataaagga atcaaatact ctcgttgctt atgacaccga
//
LOCUS       DAPGUL010000251         2810 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.256, whole genome shotgun sequence.
ACCESSION   DAPGUL010000251 DAPGUL010000000
VERSION     DAPGUL010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2810)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2810)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2810
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.256"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            212..936
                     /locus_tag="RHX21_004781"
                     /pseudo
     CDS             212..936
                     /locus_tag="RHX21_004781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313352.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            894..1571
                     /gene="bglJ"
                     /locus_tag="RHX21_004782"
     CDS             894..1571
                     /gene="bglJ"
                     /locus_tag="RHX21_004782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418786.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator BglJ"
                     /protein_id="HDV1989830.1"
                     /translation="MEHSRIKKRNVALIEKCVMSSIGIESLFRKFAGNPYKLHTYTSQ
                     ESFQDAMSRISFAAVIFSFSAMRSERREGLSCLTELAIKFPRTRRLVIADDDIEARLI
                     GSLSPSPLDGVLSKASTLEIFHQELFLSLNGVRQATDRLNNQWYINQSRTLSPTEREI
                     LRFMSRGYSMTQIAEQLKRNIKTIRAHKFNVMSKLGVSSDAGLLEAADILLCMRHCEA
                     SNVLHPY"
     gene            complement(1609..2397)
                     /gene="fhuF"
                     /locus_tag="RHX21_004783"
     CDS             complement(1609..2397)
                     /gene="fhuF"
                     /locus_tag="RHX21_004783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore-iron reductase FhuF"
                     /protein_id="HDV1989831.1"
                     /translation="MAYRSAPLYEDVIWRTHLQPQDAGLAQAVRATIAEHREHLLEFI
                     RLDEPAPLNAMTLAQWSSPNALSSLLAVYSDHIYRNQPTMIRENKPLISLWAQWYIGL
                     MVPPLMLALLTQEKALDVSPEHFHAEFHETGRAACFWVDVCEDKNATPHSPQQRMERL
                     ISQALVPVVQALEATGEINGKLIWSNTGYLINWYLTEMKQLLGEATVESLRHALFFEK
                     TLTTGEDNPLWRTVVLRDGLLVRRTCCQRYRLPDVQQCGDCTLK"
     gene            2538..2774
                     /locus_tag="RHX21_004784"
     CDS             2538..2774
                     /locus_tag="RHX21_004784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313355.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1435 domain-containing protein"
                     /protein_id="HDV1989832.1"
                     /translation="MLQRTLGSGWGVLLPGLLIAGLMYADLSPDQWRIVILMGLVLTS
                     VMLYHKQLRHYVLLPSCLALIAAIMLMIMNLNQG"
BASE COUNT          747 a          601 c          703 g          759 t
ORIGIN      
        1 taaatgtctc caggctattt caccaggtta tcatttgatg ctaaccttct gacacatgca
       61 gtggagttgt tgtgcagcag gagtatgctg atatgaaagt gaatgctaag gataatttat
      121 tcgcttaatc tattaatttg ctggaaacat ttaaggaatg aatatcctga ataaaccatc
      181 atgattttta gacagtggat gtggaggaaa tatgttgcca ggatgctgca aaaatggaat
      241 tgttatcagt aaaatacctg ttatgcaagc agggttaaaa gaggtcatga ggactcactt
      301 ccctgaatat gaaataatat ccagcgcctc tgcggaggac cttaccttat tacaattacg
      361 tcgttccgga ttagtcattg ctgatttagc cggtgaaagt gaagatcctc gttctgtttg
      421 tgaacattat tattctttaa tctcacaata tcgggaaatt cactgggttt tcatggtgtc
      481 acgctcctgg tattcccagg cagtagaatt gctcatgtgc cctacggcga cgttattgtc
      541 tgatgttgaa cccattgaga atctggtcaa gaccgtacgt tccggcaata cgcacgcaga
      601 gcgtatcagc gccatgctga cctctccggc aatgaatgaa actcatgatt ttagctatcg
      661 ctccgtcatt ctcactcttt cagagcgcaa ggtactgcgg ctattaggta aaggatgggg
      721 catcaaccag atagcttcgt tgcttaagaa aagtaataaa actatcagcg cccaaaaaac
      781 agtgcgatgc gtcgactggc aattcacagc aacgctgaaa tgtatgcatg gataaatagc
      841 gcgcagggtg caagagaact taacttgcct tctgtttatg gagatgccgc agaatggaac
      901 acagccgaat taagaagaga aatgtcgcac tcatagaaaa atgcgtcatg agcagtatcg
      961 gtattgagag tttattcaga aagtttgcgg gtaaccctta taagctccat acctatacca
     1021 gtcaggagtc atttcaggat gccatgtcgc ggatctcatt tgcggcggtc attttttctt
     1081 tttctgccat gagaagtgag cgcagagagg gattatcttg cctgactgaa ctggcgatta
     1141 agtttccgcg tacccggcgt ttagttattg cggatgatga tattgaagct cggctgattg
     1201 gttcattgtc gccatcaccg ctggacggtg tattaagtaa agcgtcaacg ctggagattt
     1261 ttcatcagga actctttttg tcattaaatg gtgtacgtca ggcgaccgac cgactgaaca
     1321 atcagtggta cattaaccaa agccggacgc taagcccgac ggagagagaa atattgcgct
     1381 ttatgtcgcg tggctactca atgacacaaa ttgccgagca gcttaaacgc aatatcaaaa
     1441 cgatccgtgc acataaattt aatgtgatgt cgaaactggg cgtcagttct gatgcagggt
     1501 tgttggaggc cgcagatatt ctgttatgta tgcggcattg cgaagcaagt aatgtgttgc
     1561 atccctatta atctgcatga tgccgggttt acttccccgg cagtgctttc atttcagcgt
     1621 acaatcgcca cattgctgca catccggtaa gcgataacgc tggcagcagg tccggcgcac
     1681 cagcaggccg tcgcgtagca ccacggtacg ccagagtgga ttatcttcac cggtagtaag
     1741 cgttttctca aaaaagaggg catggcgcag cgattcaacc gtcgcctcgc cgagcagttg
     1801 cttcatctca gtaagatacc agttgatcaa ataaccggta ttactccaga taagtttgcc
     1861 gttgatctct ccggtcgctt ctagtgcctg cacaaccgga accagcgcct ggctgattaa
     1921 cctttccatt cgctgctgcg gcgaatgtgg tgttgcgttt ttatcttcac acacatcgac
     1981 ccagaaacag gcggcacggc cggtttcgtg aaactcagca tggaaatgtt ccggcgacac
     2041 atctaatgcc ttttcctgcg tcagtagcgc cagcattaat ggtggcacca tcaggccgat
     2101 ataccattgt gcccatagtg agatcagcgg tttgttctcg cggatcatcg ttggttggtt
     2161 gcgatagata tgatcggaat agaccgcgag tagagaactt agcgcattcg gtgatgacca
     2221 ttgcgccagc gtcatggcgt taagcggagc gggttcatcc aggcggataa actccagcaa
     2281 atgttcacga tgttcggcga tcgtcgcacg tacggcttgt gcaagcccag catcctgtgg
     2341 ctggagatgc gttcgccaga taacatcttc atagagcggt gcggaacgat aggccataat
     2401 cgggatagta atctaaatga taatgattgc taatcctagc gataggttta cccgatagca
     2461 agggatttct ctggcttgca aatgataaaa attatcatat gatattggtt atcattatca
     2521 atgaaagaga tgaaaccatg ttgcaacgta cgctgggcag tggctgggga gtgttgctgc
     2581 caggattgct gattgcaggg ctgatgtatg cggatttatc accggatcag tggcggattg
     2641 tcattctgat gggattagta ttgacgtcgg tgatgctgta tcacaaacag ttacggcatt
     2701 acgttttgct accatcgtgc ctggcgctta ttgctgccat catgctgatg ataatgaatt
     2761 tgaatcaggg atgaaaaatc aaggaagaaa caagaaagga agtaaagata
//
LOCUS       DAPGUL010000252         2780 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.257, whole genome shotgun sequence.
ACCESSION   DAPGUL010000252 DAPGUL010000000
VERSION     DAPGUL010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2780
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.257"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            49..1002
                     /gene="ompT"
                     /locus_tag="RHX21_004785"
     CDS             49..1002
                     /gene="ompT"
                     /locus_tag="RHX21_004785"
                     /EC_number="3.4.23.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="omptin family outer membrane protease OmpT"
                     /protein_id="HDV1989833.1"
                     /translation="MRAKLLGIVLTTPIAISSFASTETISFTPDNINADISLGTLSGK
                     TKERVYLAEEGGRKVSQLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMV
                     DQDWMDSSNPGTWTDESRHPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYS
                     FTARGGSYIYSSEEGFRDDIGSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTF
                     KYSGWVEASDNDEHYDPGKRITYRSKVKDQNYYSVAVNAGYYVTPNAKVYVEGAWNRV
                     TNKKGNTSLYDHNDNTSDYSKNGAGIENYNFITTAGLKYTF"
     gene            1189..2673
                     /locus_tag="RHX21_004786"
     CDS             1189..2673
                     /locus_tag="RHX21_004786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDV1989834.1"
                     /translation="MRKIITHFKVVLTLLLPVTVSAQQIQWQSCMASQFNHWFGEEKP
                     SPDLLCGYLSVPLKYTDTGGDASYEKKSQVKLALTKLPAKSKHKGSILIISGGPGLPG
                     INPYINFDWPVTNLRESWDIIGFDPRGVGQSTPTINCRQSDTETQENITEKQQVLNKI
                     NACIHNTGAEVIRHIGSNEAVYDIDRIRQALGDKQLTAVAYSYGTQIAALYAERFPYN
                     VRSIVLDGVVDIDDLEDNFTWQLKQAQSYQETFDRFASWCARTKSCPLSSDRDKAITQ
                     FHELLSKLHHKPLLDSKGENISSDELISLTTDLLLWRSSWPTLATAIRQFSQGIVSNE
                     IETALSAPIASEESSDASGVILCVDQGDEQLTPEERKSRKDALANAFPAINFDNGRSD
                     SPDFCELWPIHSDLNKTRLKNTVLPSGLLFVAHKYDPTTPWINARKMAEKFSSPLLTI
                     NGDGHTLALTGVNLCVDKAVVHYLITPQKIENIYCPGNSEAEIQ"
BASE COUNT          887 a          591 c          565 g          737 t
ORIGIN      
        1 ataaaaaata catattcaat cattaaaacg attgaatgga gaacttttat gcgggcgaaa
       61 cttctgggaa tagttctgac aacccctatt gcgatcagct cttttgcttc taccgagact
      121 atatcgttta ctcctgacaa cataaatgcg gacattagtc ttggaactct gagcggaaaa
      181 acaaaagagc gcgtttatct agctgaagaa ggaggccgaa aagtcagtca actcgactgg
      241 aaattcaata acgctgcaat tattaaaggt gcaattaatt gggatttgat gccccagata
      301 tctattgggg ctgcgggctg gactactctc ggcagccgag gtggcaatat ggtcgatcag
      361 gactggatgg attccagtaa ccccggaacc tggacagatg aaagtaggca ccctgataca
      421 caactcaatt atgccaacga atttgatctg aatatcaaag gctggctcct caacgaaccc
      481 aattaccgcc tgggactcat ggccggatat caggaaagcc gttatagctt tacagccaga
      541 ggtggttcct atatctacag ttctgaggag ggattcagag atgatatcgg ctccttcccg
      601 aatggagaaa gagcaatcgg ctacaaacaa cgttttaaaa tgccctacat tggcttgact
      661 ggaagttatc gttatgaaga ttttgagcta ggtggcacat ttaaatacag cggctgggtg
      721 gaagcatctg ataacgatga gcactatgac ccaggaaaaa gaatcactta tcgcagtaaa
      781 gtcaaagacc aaaattacta ttctgttgca gtcaatgcag gttattacgt aacacctaac
      841 gcaaaagttt atgttgaagg cgcatggaat cgggttacga ataaaaaagg taatacttca
      901 ctttatgatc acaatgataa cacttcagac tacagcaaaa atggtgcagg catagaaaac
      961 tataacttca tcactactgc tggtcttaag tacacctttt aacgaagtta accagatttt
     1021 ctccccggtg gtattgtata accccgggga atttgtttac agttacaagt aggcaatatc
     1081 cactaatttt gtaagcattt aacctatgtc ataacgtgta atctcttacc gcaacacaag
     1141 acctcaatat attcaaatct tatctttatt ccgatattca gagacacaat gcgaaaaata
     1201 atcactcatt tcaaagttgt tttaacgtta cttctaccag taaccgtatc tgcccagcag
     1261 atacagtggc aatcctgtat ggccagtcaa ttcaaccact ggtttggtga ggaaaaaccg
     1321 tctcctgact tactatgtgg ttatttgtct gttccattaa aatatacaga cacaggcgga
     1381 gatgcttctt atgaaaaaaa atcacaagtc aaactagcgt tgacaaaatt gccggcaaaa
     1441 agcaagcata aaggaagtat cctgataata agtggtggtc ccgggttacc aggcataaat
     1501 ccttatatta actttgactg gccagtcaca aatcttcgtg agtcatggga tattattgga
     1561 tttgatcctc gaggcgtcgg acagtccact ccgacaataa actgccggca atcagataca
     1621 gagactcagg aaaacataac cgaaaagcaa caagtattaa ataaaattaa tgcctgtatc
     1681 cataataccg gagccgaagt cattcgccat atcggctcta acgaggctgt atacgatatt
     1741 gatcgtatta ggcaagcctt gggggataaa caactgacag ccgtggcgta ttcgtatgga
     1801 actcaaattg cagccttata tgcagaacgt tttccctaca acgtaagatc tatcgttctt
     1861 gatggagtcg tcgatatcga tgacctggag gacaacttca catggcaact caaacaggca
     1921 cagagttatc aggaaacgtt tgatcgcttt gcatcctggt gtgcgcgtac aaaaagttgc
     1981 ccgctttctt cagacagaga taaggcaata actcagttcc atgagctatt atcaaaatta
     2041 catcacaaac ctttattaga cagtaaggga gaaaatatat cttcagatga actcatatca
     2101 ttaacaacag accttctgct atggcgttca tcatggccaa cccttgcaac tgccatacgc
     2161 cagttctctc aggggattgt cagtaatgaa attgaaactg cgctcagtgc tccgatagcc
     2221 tcagaagagt caagcgatgc ttcgggggta atcctctgtg tagatcaggg ggatgagcaa
     2281 ttaacaccag aagagcgaaa atcccgaaaa gacgctcttg cgaatgcctt cccggctatt
     2341 aactttgaca atggacgttc cgattcacct gatttttgtg aattatggcc aatacatagc
     2401 gacctgaaca aaactcgcct gaaaaatact gttctgccct ctggtttact gtttgtagca
     2461 cacaaatacg acccaacaac gccctggatt aatgcccgta agatggcaga gaaattttcc
     2521 agcccgttac taacaataaa tggtgatggg catacattag ctctcaccgg agttaattta
     2581 tgtgtagata aagcagttgt acattacctg atcactccac aaaaaataga aaatatatac
     2641 tgcccaggaa attctgaagc agaaatacaa taatttcaaa atattccgct atttgctccc
     2701 aatgcaaaac atatattgca ttgggagcat attcatattt ttgttattat tgtatgaaat
     2761 cgtctcatgt acacggtcct
//
LOCUS       DAPGUL010000253         2724 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.258, whole genome shotgun sequence.
ACCESSION   DAPGUL010000253 DAPGUL010000000
VERSION     DAPGUL010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2724)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2724)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2724
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.258"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            1..2649
                     /locus_tag="RHX21_004787"
                     /pseudo
     CDS             1..2649
                     /locus_tag="RHX21_004787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308264.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
BASE COUNT          646 a          707 c          956 g          415 t
ORIGIN      
        1 cgggtgacgg agcaggtcaa cccggagggg ctggactatc gctttgagta cgggcaggac
       61 cgtgtgacca tcacggacag cctgaaccgg cgggaggtgc tgtacacgga gggcgaaggc
      121 ggcctgaagc gtgtggtgaa gaaggagcat gcggacggca gcatcacccg cagcgagtat
      181 gatgaggcgg ggaggctgaa ggcacagacg gatgcggcgg gacggcggac ggagtaccga
      241 ctgcatatgg cgtctggaaa gctgacttca gtgatactgc cggatggcag gacggtacgg
      301 tatggctata acagccagcg gcaggtgacg tcggtgacgt acccggacgg gcttcgcagc
      361 agccgggagt atgatgagaa gggaaggctg gcggcggaga cctcacgcag cggtgagacg
      421 acgagttaca gctatgatga cccggcgagt gagctgccga cagggataca ggacgcgacg
      481 ggcagtacaa aacagatggc atggagccgt tacggtcaac tgctggcctt tacggactgc
      541 tcggggtaca cgacgcggta tgagtacgac cggtacggtc aacaaatcgc cgttcaccgg
      601 gaagaaggca tcagcactta cagcagttat aacccgcgtg ggcaaatggt cagtcagaag
      661 gatgcgcagg ggcgtgaaac ccgttatgag tacagcgccg caggagacct gacagcaacg
      721 gtatcaccgg acggtaaacg cagcaccatc gcatatgata aacgcgggcg tccggtgagt
      781 gtgacggaag gtggactgac gcgcagcatg gggtatgacg ctgccgggcg catcaccgtg
      841 ctgaccaacg agaacggcag ccagtccacg ttccggtatg acccggtgga caggctgact
      901 gaacagcgcg gttttgacgg ccggacgcaa cgttaccact atgacctgac cggaaaactc
      961 acgcagagtg aagacgaggg gcttatcacc ctctggcact acgatgcgtc ggaccgcatc
     1021 acgcaccgga cggtgaacgg cgacccggca gagcagtggc agtatgatga gcacgggtgg
     1081 ttaaccaccc tcagccatac ctgtgaaggc caccgcgtgt cggtccacta cggctatgac
     1141 gataaaggcc gcctgacggg tgaacggcag acggtggaga acccggagac aggggagatg
     1201 ctgtgggagc atgagacggg gcatgcgtac agcgaacagg ggctggcgac ccgtcaggag
     1261 ccggacggtc tgccgccggt ggagtggctg acgtatggca gcggttatct tgcggggatg
     1321 aagctgggcg gaacgccgct ggtcgagtac acgcgggacc ggctgcaccg cgagacggcc
     1381 cgtagcttcg gcggggcggg cagtacagcg gggtacgaac aggccacggc gtacaccctc
     1441 acagggcagc tacagagcag gcacctgaac cttccgcagc ttgactgtga ctatacgtgg
     1501 aacgataacg gacaactggt gcgcatcagc ggcccgcagg agtgccggga gtaccgttac
     1561 agcggcacgg gaaggctgac gggcgtccac actacggcag cgaacctgga tatcgatatc
     1621 ccgtatgcga cggacccggc aggaaaccgg ctgccggacc cggaactgca cccggacagc
     1681 accctcacgg cgtggccgga taaccgcatc gcggaagatg cgcactatgt ctaccgctac
     1741 gatgaatacg gcaggctggc ggagaagacg gaccgcatcc cggaaggggt gatacggatg
     1801 cacgacgagc ggacccacca ctaccactac gacagccagc accgtctggt gttctacacg
     1861 cggatacagc acggtgagcc gcaggtggag agccgctacc tctatgaccc gctgggccgc
     1921 cggacgggaa aacgggtgtg gcggcgggag cgtgacctga cggggtggat gtcgctgtcg
     1981 cgtaaaccgg aggagacctg gtacgggtgg gacggtgaca ggctgaccac tgtacagacc
     2041 caacagacaa gaatccagac ggtataccag ccgggaagct tcacgccgct cctgagaatc
     2101 gaaacagaga atggtgaaca ggcgaaggcg cggcaccgta gcctggcgga ggtgttgcag
     2161 gaggacacgg gtgtgacgct accggcggag ctggcggtga tgctggggag gctggagcgg
     2221 gaactgcggc agggcagcgt gagtgaagaa agccagcagt ggcttgcgca gtgcgggctg
     2281 acggcggaac agatggccgc gcaactggag gcggaataca tcccggagag gaaacttcat
     2341 ctttaccact gtgaccaccg tgggctgccg ctggcgctta tcagcccgga aggggaaacg
     2401 gcgtggcagg gggagtatga cgagtgggga aacctgctgg gcgaggaaag cgcgcagcac
     2461 cttcagcagt cactccgtct gccgggacag cagtatgatg aggagtcggg gctgtactac
     2521 aaccgcaacc ggtactatga tccgttgcag gggagatata tcacccagga cccgataggg
     2581 ctgagaggtg aatggaatct gtataaatat ccattaaacc ctgttcggtt tatagattct
     2641 ttgggtttaa aattccatgt taacggtgat ccaagtgatt ttaatcaggc tgttgagtat
     2701 ttaaaacaag attcacaaat gaaa
//
LOCUS       DAPGUL010000254         2722 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.259, whole genome shotgun sequence.
ACCESSION   DAPGUL010000254 DAPGUL010000000
VERSION     DAPGUL010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2722)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2722)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2722
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.259"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            85..2364
                     /gene="ydeP"
                     /locus_tag="RHX21_004788"
     CDS             85..2364
                     /gene="ydeP"
                     /locus_tag="RHX21_004788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance putative oxidoreductase YdeP"
                     /protein_id="HDV1989835.1"
                     /translation="MKKKIESYQGAAGGWGAVKSVANAVRKQMDIRQDVIAMFDMNKP
                     EGFDCPGCAWPDPKHSASFDICENGAKAIAWEVTDKQVNASFFAENTVQSLLTWGDHE
                     LEAAGRLTQPLKYDAVSDCYKPLSWQQAFDEIGARLQSYSDPNQVEFYTSGRTSNEAA
                     FLYQLFAREYGSNNFPDCSNMCHEPTSVGLAASIGVGKGTVLLEDFEKCDLVICIGHN
                     PGTNHPRMLTSLRALVKRGAKMIAINPLQERGLERFTAPQNPFEMLTNSETQLASAYY
                     NVRIGGDMALLKGMMRLLIERDDAASAAGRPSLLDDEFIQTHTVGFDELRRDVLNSEW
                     KDIERISGLSQTQIAELADAYAAAERTIICYGMGITQHEHGTQNVQQLVNLLLMKGNI
                     GKPGAGICPLRGHSNVQGDRTVGITEKPSAEFLARLGERYGFTPPQAPGHAAIASMQA
                     ICTGQARALICMGGNFALAMPDREASAVPLTQLDLAVHVATKLNRSHLLTARHSYILP
                     VLGRSEIDMQKSGAQAVTVEDSMSMIHASRGVLKPAGVMLKSECAVVAGIAQAALPQS
                     VVAWEYLVEDYDRIRNDIEAVLPEFADYNQRIRHPGGFHLINAAAERRWMTQSGKANF
                     ITSKGLLEDPSSAFNSKLVMATVRSHDQYNTTIYGMDDRYRGVFGQRDVVFMSAKQAK
                     ICHVKNGERVNLIALTPDGKRSSRRMDRLKVVIYPMADRSLVTYFPESNHMLTLDNHD
                     PLSGIPGYKSIPVELEPSN"
     gene            2612..>2722
                     /gene="safA"
                     /locus_tag="RHX21_004789"
     CDS             2612..>2722
                     /gene="safA"
                     /locus_tag="RHX21_004789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system connector SafA"
                     /protein_id="HDV1989836.1"
                     /translation="MHATTVKNKITQRDNYKEIMSVIVVVLLLTLTLIAIF"
BASE COUNT          724 a          636 c          668 g          694 t
ORIGIN      
        1 catgttggcg ataatccctt tgtatgtact gtgcatcatc gctattacaa atcctaataa
       61 ttcatttcca cacaggataa gtagatgaag aaaaaaattg aatcctacca gggtgctgcc
      121 ggtggttggg gtgctgttaa atccgtagcg aatgcagtac gtaagcagat ggatatacgc
      181 caggatgtta ttgccatgtt tgacatgaat aagccagagg gctttgactg tccgggttgt
      241 gcatggccag atcctaagca cagtgcgtca ttcgacattt gtgaaaacgg cgcaaaagca
      301 atcgcctggg aagtcacgga taagcaggta aacgcctctt tctttgctga gaatacggtt
      361 caatcattac ttacctgggg agaccacgag cttgaggctg cggggcgact cactcagcct
      421 ttgaaatatg atgccgtcag cgactgttac aagccattaa gctggcaaca agctttcgat
      481 gaaattggcg cacgccttca aagctatagt gatcccaatc aggttgaatt ctatacttcg
      541 ggccgcactt ccaatgaagc tgcctttctt tatcagcttt ttgcccgtga atacgggagc
      601 aataactttc ccgactgctc caacatgtgc catgaaccga caagcgtggg tttggcagcg
      661 agtatcggtg taggtaaagg gaccgtgttg ctggaagact ttgagaagtg cgatttagtc
      721 atttgcattg ggcataaccc tggtacaaac caccctcgca tgctgacttc gttgcgcgct
      781 ttagtgaaac ggggagcgaa aatgatcgcc atcaatcctc tacaggaacg tggcctggag
      841 cgatttactg caccgcaaaa cccgtttgaa atgctgacga actctgagac tcagttggcc
      901 agtgcctact ataacgtgcg cattggtggt gatatggcgt tgctcaaggg gatgatgcgc
      961 ctgttaattg agcgcgatga tgctgcaagc gccgcaggtc ggccctcatt gctggatgac
     1021 gaatttattc aaacgcatac cgtcggcttt gacgagctac gccgtgacgt tctcaattcc
     1081 gagtggaaag atatcgaacg tatttctgga ttaagtcaga ctcaaatcgc cgaactggct
     1141 gatgcatatg ccgctgccga acgaaccatt atctgttacg gaatggggat cactcagcac
     1201 gaacatggta cccagaatgt acagcaactg gtcaatctgc tgttgatgaa aggtaacatt
     1261 ggcaagcctg gtgcgggtat ctgcccacta cgtggccact ctaatgtaca gggcgaccga
     1321 accgtcggta tcaccgagaa accgtctgca gagtttctgg ctcgcctggg tgagcgctat
     1381 ggcttcacac cacctcaagc acctggacat gctgcaattg ccagcatgca agcaatatgt
     1441 acagggcagg ctcgagcatt gatctgcatg gggggcaact ttgcactggc aatgccagat
     1501 cgggaagcga gcgctgtacc gttaacgcaa ttagatctgg cggtacacgt agccactaag
     1561 cttaaccgct ctcatctgct gaccgcacgg catagctata ttctgccggt tctgggacgt
     1621 agcgagattg acatgcaaaa aagcggtgcg caggcggtaa ccgttgagga ttcaatgtcg
     1681 atgattcatg cctcgcgtgg cgtgttaaaa cccgccggtg taatgctgaa atcagagtgt
     1741 gcagtggtcg cgggaatcgc gcaggcagca ctaccccaga gcgtggtagc ctgggagtat
     1801 ctggtggaag attatgatcg cattcgcaat gacattgaag ctgtgctgcc agagttcgcc
     1861 gattataacc agcgcatccg acatcctggt ggttttcacc tgataaacgc tgctgctgaa
     1921 aggcgctgga tgactcagtc aggtaaggct aatttcatta ccagcaaagg gctgttagaa
     1981 gatccctctt cagcgtttaa cagtaagctg gtcatggcga cagtacgcag ccacgatcag
     2041 tacaacacga cgatttatgg tatggatgat cgctatcgag gggtattcgg tcaacgagat
     2101 gtggtcttta tgagtgctaa acaagctaaa atttgccatg taaaaaacgg cgaaagagtt
     2161 aatcttattg cgcttacgcc agacggtaag cgcagctcac gccgcatgga tagattaaaa
     2221 gtggtcattt accctatggc tgaccgctca ctagtgacct attttccaga atcgaatcac
     2281 atgctaacac ttgataacca cgatccatta agtggcattc ctggctataa aagtattccg
     2341 gttgaattag aaccatcaaa ttaatgcctc ttctcatttc ttctgctgtc atccgcacag
     2401 cagaagaatc cctcattgac tattatcgcg caatttgctc acatggatta aattaaacta
     2461 catactataa gatataaact tctgcctaca gctgtaagaa actccgttca gtactgaagc
     2521 gccagtccta tttcctcttt tctccggcct gttatattaa gcatactgat taacgatgct
     2581 taacgttatt cgcttaataa acatatttga aatgcatgcg accacagtga aaaacaaaat
     2641 cacgcaaaga gacaactata aagaaatcat gtctgtaatt gtggttgtct tattactgac
     2701 ccttacgttg atagccattt tt
//
LOCUS       DAPGUL010000255         2699 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.260, whole genome shotgun sequence.
ACCESSION   DAPGUL010000255 DAPGUL010000000
VERSION     DAPGUL010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2699)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2699)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2699
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.260"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            28..582
                     /locus_tag="RHX21_004790"
     CDS             28..582
                     /locus_tag="RHX21_004790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HDV1989837.1"
                     /translation="MNKKLMYIFAIFIVAAITCISQPKKTTLRDKAMVNYAFDYLSSP
                     GSLPFTTAATELSAIHGHSTSQYRLGEFYLHGSDGKPLDYTQARYWYEQSAEQENPRA
                     QSKLGWIYLKGLGVKPDTRKAILWYKEAAEQGYAHAQYTLGLIYRNGSGINVNHYESQ
                     KWLKLAAKQHYKNAERLLAGLPAH"
     gene            complement(592..2019)
                     /locus_tag="RHX21_004791"
     CDS             complement(592..2019)
                     /locus_tag="RHX21_004791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="HDV1989838.1"
                     /translation="MKNCWKILEIEETTDVDIIRRAYLALLPSFHPETDPQGFKQLRQ
                     AYEEALRIAQSPAKSVWQPEEYEVAEHEILLAFRALLASDSERFLPSAWQRFIQQLNY
                     CSMEEIDELRWSLCTIAMNTAHLSFECVVLLAERLRWLQEENVGEIDEEELESFLYAI
                     AKGNVFNFQTILHLPVAVQNDTIDFYQMFARIWSSHPEWLTLYLAQHRAVIIPDDAKL
                     HRNLLRWYSAGRLGIPELLDYARSWREAESDNEDARYYEYAQRVYCGEGESLLAELCD
                     YWREYPSTQADALILQWCRQHRVDYYPLVVMMIEARELVNDQGKPLLYIPGDSARTRF
                     HLYEILSDEKLSALGRSLVEMVLHKGRKPRISLTRDTEHPLWPLYLVAKQLVQANQPT
                     EESLMPIVSRLDAEDRCPLEALIIRRLLIQAANFTEKQTVEPEPQPQPMPVDDGGPGC
                     LGIIKIIFYIFIFAGLIGKILHLFG"
     gene            complement(2016..>2699)
                     /locus_tag="RHX21_004792"
     CDS             complement(2016..>2699)
                     /locus_tag="RHX21_004792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
                     /protein_id="HDV1989839.1"
                     /translation="LFALSTPMEIRNECCLPSHSSPKMYLGTCFFDLSSSWGIDARDD
                     LLRTIHRMIDNGHAARLAGFYHRWFRYSPCEWRDYLAELNEQGQAYAQFVASTAECCG
                     EGGIKAWDYVRMGFLSRMGVLNNWLSEEESLWIQSRIHLRALRYYRNWRQYFAGYTFG
                     RQYWQSPEDDHLQLLREFLARKEYDDSGNDMFYQLFASDDAYYPTLSWQPLAYYSACP
                     ETLKDMSDL"
BASE COUNT          782 a          643 c          601 g          673 t
ORIGIN      
        1 ataaaaagaa aatcgaagca ttcacatatg aataaaaaat taatgtatat attcgcaata
       61 tttatagttg cagcaattac ctgtattagc caacccaaga aaacaacgtt gcgtgataaa
      121 gccatggtga attatgcctt tgattattta agctcaccgg gcagtctacc gtttaccacg
      181 gcggccacgg agctttccgc gattcatggt cactcaacgt cgcaatatcg ccttggagaa
      241 ttttatcttc atggtagcga cggtaaacca ctggattata cacaggcgag atactggtat
      301 gagcaatcag cagaacagga aaatccgcgc gcacaaagca aactggggtg gatctacctc
      361 aaaggtctgg gggtcaaacc cgacacccgt aaagcaattc tctggtataa ggaagcagct
      421 gaacaagggt atgctcatgc tcaatatact ttaggtttga tctacagaaa tggctcaggt
      481 attaatgtta accattatga atctcaaaaa tggttaaaac tggccgccaa acaacattac
      541 aaaaatgcgg aaagattact tgccgggctt cccgcacatt aacgtcgact gtcaaccgaa
      601 cagatggagt attttcccta tcaaaccagc aaagataaaa atatagaaaa taattttaat
      661 gatgcccaga cagcctggcc caccatcgtc aacgggcatt ggctgcggtt gcggctccgg
      721 ttcaacagtt tgcttctcgg taaaattcgc cgcctgaatt aataatcgac gaataattaa
      781 tgcttccagt ggacaacgat cttctgcatc aaggcggctc acaatcggca ttaatgattc
      841 ttcggttggt tggttcgcct gcactaattg tttggcaact aaatataatg gccataaggg
      901 atgttctgta tcacgcgtga gtgagatccg cggcttacgt cctttgtgca aaaccatctc
      961 gaccagtgaa cgccccagag cagagagttt ttcatcgctg agtatttcgt ataaatgaaa
     1021 acgcgtacgg gcgctgtcgc cggggatata aagtagcggt tttccctgat cgttaaccag
     1081 ttcacgagct tcaatcatca tcaccactaa cgggtaataa tcgacccgat gctgacggca
     1141 ccattgcaat attaaagcat ccgcctgggt ggagggatac tcgcgccagt agtcacaaag
     1201 ttctgccagc aagctttcgc cttctccaca atagacgcgt tgtgcgtatt cataataacg
     1261 cgcatcttca ttatcagatt cagcttcccg ccacgaccgg gcgtaatcca ggagttcggg
     1321 aattcccagg cgacctgcgc tataccagcg gagtaaattt ctgtgcagtt ttgcatcatc
     1381 ggggataatc actgcgcgat gttgcgctaa atacaatgtc agccattctg gatgcgatga
     1441 ccaaatccga gcgaacattt ggtaaaaatc gatggtgtca ttttgcacgg caacgggcag
     1501 atgcagaatg gtctggaagt taaaaacatt ccccttcgca atggcatata aaaaggattc
     1561 cagttcttct tcgtctattt ccccgacgtt ttcctcctgc aaccaccgca atctttctgc
     1621 taataacacc acgcactcga aggataaatg ggcagtgttc atggcgattg tgcacagcga
     1681 ccagcgtaat tcatcaatct cttccatcga gcaataattt aattgctgaa tgaatcgctg
     1741 ccaggcggag ggcagaaaac gttcgctatc agaggcaagt aacgcacgaa aggcgagcag
     1801 aatttcatgt tctgctacct catattcttc tggttgccaa acagatttag caggcgactg
     1861 cgcaatccgt agcgcctcct catacgcctg acgaagttgt ttaaaaccct gcggatcggt
     1921 ttctggatga aaggacggta acagcgccag ataagcgcgg cggataatat cgacgtcagt
     1981 cgtttcctct atttcgagaa tcttccagca atttttcata ggtcgctcat atccttaagc
     2041 gtttccgggc atgcagaata gtaagccaat ggttgccagg acaaggtagg gtaatacgca
     2101 tcatcactgg caaataattg ataaaacata tcattgccgg aatcgtcgta ttctttacgc
     2161 gctaagaatt cgcgtaataa ctgcagatga tcatcttcgg gagactgcca atattgccga
     2221 ccaaaggtat aaccggcaaa gtattgccgc cagttacgat aataacgtag agcccgtaga
     2281 tgaatgcgcg actggatcca tagactttct tcttcgctca accagttatt aagtacgccc
     2341 attcggctta aaaaacccat ccggacataa tcccaggctt taattcctcc ctcaccacag
     2401 cattcggcgg tgctggcgac aaattgcgca taagcctgac cttgctcatt tagttcagca
     2461 agatagtcac gccattcaca tggcgaataa cgaaaccagc ggtgataaaa ccctgccaac
     2521 cgagcggcat gaccgttatc gatcattcgg tgaattgtgc gcagcaggtc atcacgggca
     2581 tcaattcccc aggaggaaga aaggtcaaaa aagcatgtac ctaaatacat tttgggtgat
     2641 gaatgcgaag gtaaacagca ttcattgcgt atttccatcg gagtggaaag tgcaaacaa
//
LOCUS       DAPGUL010000256         2680 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.261, whole genome shotgun sequence.
ACCESSION   DAPGUL010000256 DAPGUL010000000
VERSION     DAPGUL010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2680)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2680)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2680
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.261"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(188..1222)
                     /locus_tag="RHX21_004793"
     CDS             complement(188..1222)
                     /locus_tag="RHX21_004793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011095211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HDV1989840.1"
                     /translation="MTASATPTNITHKFIVHIMNKEQQGLATIIPCPSEKPVQQASKD
                     LSNALTERYSGRAGKGYGKFEDDRDSYPMGNIVDDYFVNKTHSFYDTSIRMINHLKAR
                     ADDESMSTGGYVIIAHNEVNGNHYLMVAILTSAVGSSVHDFEIQESEYLDIAKLRVAG
                     RIDLTGRQNGKERYISFLKGQNSVAGYFKKFLGCNDILIAKQETTKLRNALLEFATER
                     GFEPEAREEFLNKAHEKLKNLNRSGETFDTQIFANEIWPTAPELLVEKLTNDDLEFSD
                     GFVPDGNVIRGLVSFKGKSKHWSLKFERAALHDGSVLYDSENDKLILTEIPDTLRSEI
                     LSELGEEDEQ"
     gene            1513..1839
                     /locus_tag="RHX21_004794"
     CDS             1513..1839
                     /locus_tag="RHX21_004794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001120497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin, lambda family"
                     /protein_id="HDV1989841.1"
                     /translation="MPHNPNTWLELVQSWWRGDTPLGAVIMSIVMAGLRIAYFGGGGG
                     WKRKTLEILLCGALTLTFASALEYVGWPKSLSVAIGGGVGLIGVDAIRGAAMRVIGNK
                     FGGSKE"
     gene            1843..2319
                     /locus_tag="RHX21_004795"
     CDS             1843..2319
                     /locus_tag="RHX21_004795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family protein"
                     /protein_id="HDV1989842.1"
                     /translation="MQVLNSQRKAFLDMLAWSEGTDNGRQPTRNHGYDVIVGGELFTD
                     YSDHPRKLVTLNPQLKSTAAGRYQLLSRWWDAYRKQLGLKDFSPKNQDAVALQQIKER
                     GALPMIDRGDIRQAIDRCSNIWASLPGAGYGQFEHKADSLIAKFKEAGGTVREIEV"
     gene            2536..>2680
                     /gene="rzoD"
                     /locus_tag="RHX21_004796"
     CDS             2536..>2680
                     /gene="rzoD"
                     /locus_tag="RHX21_004796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prophage lysis lipoprotein RzoD"
                     /protein_id="HDV1989843.1"
                     /translation="MRKLKMMLCVMMLPLVVVGCTSKQSVSQCVKPPPPPAWIMQPPP
                     DWQT"
BASE COUNT          689 a          598 c          612 g          781 t
ORIGIN      
        1 tatagtttgg cctaactcaa tgttgccaga ttcaagggtg atgccaaaat catggggatt
       61 ctctgtgata tcgttgatga tgtcacagag ctcctcgttt gaaagaatga gtgatgcttc
      121 agatagggta cctgcaaatg tagcggcctt gtaaatagtc actaagtctt tgaaggttct
      181 ctgattttta ctgctcatcc tcttcaccta attctgataa aatctctgat cttagcgtat
      241 ccggaatctc ggtaagtatc aatttatcgt tttctgaatc ataaagaacg ctgccatcat
      301 gcaaggccgc acgctcgaat ttcagagacc aatgtttgga ctttcctttg aaactaacaa
      361 gcccacgtat aacgttgcca tcaggcacga acccatcaga gaactccaga tcgtcattgg
      421 ttaacttttc aactaacaac tcaggagcag ttggccatat ctcgtttgca aaaatttgag
      481 tgtcgaaagt ttcaccagaa cgatttaaat tttttaattt ttcatgagcc ttatttagga
      541 actcttcacg tgcctctggt tcaaaacctc tttcagtagc aaattctaaa agtgcattcc
      601 gtaattttgt tgtttcttgt ttggcaatta gaatatcgtt gcaacctaaa aactttttga
      661 aataacctgc tactgaattt tgccccttta gaaagctaat atatctctct ttgccattct
      721 ggcgcccagt taagtcaatt cgtcccgcta ctcgaagttt agcaatgtct agatattcac
      781 tttcttgaat ttcaaaatcg tggactgaag agccaactgc tgaagttagg attgcaacca
      841 tcaaataatg atttccattt acctcattat gggcaattat tacataacca ccagtagaca
      901 ttgattcatc atcggctctg gcttttaaat gattgatcat tcggatacta gtatcataaa
      961 aactatgtgt tttatttacg aaataatcat caacgatatt acccataggg taactatcgc
     1021 ggtcatcttc aaatttccca tatcctttac ctgctctccc agagtacctt tcagtaagtg
     1081 cgttagagag gtcttttgat gcttgctgaa caggtttttc tgaaggacaa ggaataatgg
     1141 tggctaaccc ctgttgttcc ttgttcataa tgtgaacaat aaacttatga gtgatattag
     1201 tgggggtcgc tgatgcagtc ataacaacat ccttttaata gttttgaaca attggtgttg
     1261 ataatacttc aaaaaatact aatgcgtacg caaaaaatac agtactctgt taagagtggt
     1321 tacttcgcca cacagcttaa acccgccgtt gagcgggttt tgtcgtttct ggggctgggg
     1381 attcgttggt cctggtctat tccgcagtta tccattggtt cggcttcttt gacgtttccg
     1441 cttctaattt gctgtacatg atgttccctc aatttgcacc tgctgtatca gcgaggtgag
     1501 agataactac aaatgcctca taacccaaat acctggctgg agttggtcca gagctggtgg
     1561 cgtggagaca caccactggg cgcagtgatt atgtcgatcg ttatggctgg cttgcgcatt
     1621 gcctattttg gcggtggtgg tggctggaag cgaaaaacgc ttgagatttt actctgtggc
     1681 gctctgacgc tgacatttgc atccgcgctt gagtatgtcg gatggcctaa atcactatct
     1741 gttgccattg gtggtggggt ggggctgatc ggtgtcgatg ctattcgtgg ggctgcaatg
     1801 cgagtaatcg gtaacaagtt tggtggctct aaggagtaat ttatgcaggt actaaattcc
     1861 cagcgtaaag cttttctcga tatgttggcg tggtcagaag gaacggataa cgggcgacag
     1921 ccaacccgca atcacggcta cgacgttatt gtaggtggtg agctattcac ggattactcc
     1981 gatcatcctc gcaaacttgt cacgctaaac ccgcaactta aatcaaccgc agctggacgt
     2041 taccagcttc tttcccgttg gtgggatgcc taccgcaagc agcttggcct gaaagacttc
     2101 tctccgaaaa accaggacgc tgttgcactg cagcagatta aggagcgtgg cgctttaccg
     2161 atgattgatc gcggtgatat ccgtcaggct atcgaccgtt gcagcaatat ctgggcttca
     2221 ctgccgggcg ctggttatgg ccagttcgag cataaggctg acagcctgat tgcaaaattc
     2281 aaagaagcag gcggaacggt cagagagatt gaggtatgag cagattaacc gcgattatct
     2341 ccgctctgct catctgcatc atcgtctgca tgtcattggc tgttaatcat tatcgtgata
     2401 acgccattac ctacaaagcc cagcgcgaca aaaatgccag agaactgaag ctggcgaacg
     2461 cggcaattac tgacatgcag gtgcgccaac gtgatgtcgc tgcgctcgat gcaaaataca
     2521 cgaaggagtt agctgatgcg aaagctgaaa atgatgctct gcgtgatgat gttgccgctg
     2581 gtcgtcgtcg gttgcacatc aaagcagtct gtcagtcagt gcgtgaagcc accaccgcct
     2641 ccggcatgga taatgcagcc tccccccgac tggcagacac
//
LOCUS       DAPGUL010000257         2604 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.262, whole genome shotgun sequence.
ACCESSION   DAPGUL010000257 DAPGUL010000000
VERSION     DAPGUL010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2604
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.262"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            133..948
                     /gene="sul2"
                     /locus_tag="RHX21_004797"
     CDS             133..948
                     /gene="sul2"
                     /locus_tag="RHX21_004797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfonamide-resistant dihydropteroate synthase
                     Sul2"
                     /protein_id="HDV1989844.1"
                     /translation="MNKSLIIFGIVNITSDSFSDGGRYLAPDAAIAQARKLMAEGADV
                     IDLGPASSNPDAAPVSSDTEIARIAPVLDALKADGIPVSLDSYQPATQAYALSRGVAY
                     LNDIRGFPDAAFYPQLAKSSAKLVVMHSVQDGQADRREAPAGDIMDHIAAFFDARIAA
                     LTGAGIKRNRLVLDPGMGFFLGAAPETSLSVLARFDELRLRFDLPVLLSVSRKSFLRA
                     LTGRGPGDVGAATLAAELAAAAGGADFIRTHEPRPLRDGLAVLAALKETARIR"
     gene            985..1563
                     /locus_tag="RHX21_004798"
                     /pseudo
     CDS             985..1563
                     /locus_tag="RHX21_004798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001334685.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4238 domain-containing protein"
     gene            complement(1739..2083)
                     /locus_tag="RHX21_004799"
     CDS             complement(1739..2083)
                     /locus_tag="RHX21_004799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection protein"
                     /protein_id="HDV1989845.1"
                     /translation="MKNLLDTEGTVLFPFQTEIHFIWTIFSTVKRLVIGTRDHICQKQ
                     YWSACLCILLLMAYVGLCAAVVWFVVPWLKAFIVSKFAVSALWVTPVKRGLLWGIGKV
                     VTATCRRFTLLK"
BASE COUNT          585 a          693 c          676 g          650 t
ORIGIN      
        1 ggttaggttt tgcgatagta tatttacgag ctgattaagg tttggcatag tgtggttcgt
       61 aagaaaaatt actattatgc cttgtcctta gtcagctttt ttgttttttg tcgtgtacag
      121 agagaagccc ccatgaataa atcgctcatc attttcggca tcgtcaacat aacctcggac
      181 agtttctccg atggaggccg gtatctggcg ccagacgcag ccattgcgca ggcgcgtaag
      241 ctgatggccg agggggcaga tgtgatcgac ctcggtccgg catccagcaa tcccgacgcc
      301 gcgcctgttt cgtccgacac agaaatcgcg cgtatcgcgc cggtgctgga cgcgctcaag
      361 gcagatggca ttcccgtctc gctcgacagt tatcaacccg cgacgcaagc ctatgccttg
      421 tcgcgtggtg tggcctatct caatgatatt cgcggttttc cagacgctgc gttctatccg
      481 caattggcga aatcatctgc caaactcgtc gttatgcatt cggtgcaaga cgggcaggca
      541 gatcggcgcg aggcacccgc tggcgacatc atggatcaca ttgcggcgtt ctttgacgcg
      601 cgcatcgcgg cgctgacggg tgccggtatc aaacgcaacc gccttgtcct tgatcccggc
      661 atggggtttt ttctgggggc tgctcccgaa acctcgctct cggtgctggc gcggttcgat
      721 gaattgcggc tgcgcttcga tttgccggtg cttctgtctg tttcgcgcaa atcctttctg
      781 cgcgcgctca caggccgtgg tccgggggat gtcggggccg cgacactcgc tgcagagctt
      841 gccgccgccg caggtggagc tgacttcatc cgcacacacg agccgcgccc cttgcgcgac
      901 gggctggcgg tattggcggc gctgaaagaa accgcaagaa ttcgttaact gcacattcgg
      961 gatatttctc tatattcgcg gttcactaaa gagcaggcca tggaaaccct gggcctgtcg
     1021 tccgggggcg ataccaagga tatttttctg cggcagctcg tccagcaggt gtcacatatt
     1081 gatctcctgc tgaaaaagga ctggtacctt ctggaaacca ggccagaacg tccgttttac
     1141 gtatcagaca atcccgtagt gcttaagaac agcaatgact tcggtccgta cggtaatctt
     1201 ggtctggccg ttcgcgggat acagatttac ctccccctgt catcgacgct gatgctggcc
     1261 atgtattgcc cctccatccg tgaacagatg gttcgtcaaa agcagcatct tcaacatctg
     1321 ctcgccaggg cgccgcatct tatcccccgt cacattcggc cttttgaaag actggaacat
     1381 atccggaggt atacggacta tcttcttatg ccgcttaccc cggagcatgt cacgcattac
     1441 aattccctgc aggtggagtt cgcggagcag tacgtgttct gcggtgaaaa ggatttctct
     1501 ctggttgaga gaatgctggc cgatagtgaa cgctaccgga ctggcccgcg gtttacgttt
     1561 tagtccgaat tccggcctca cctgtgccgg aaaatgacgg cgggagcccc tgttgtacag
     1621 aggagttttg ccgtgttgca cccacgcgaa agcggcagtg gtcacaggga ccaccgccgt
     1681 aaggagatgg tgagtatctg ttgacattca ccatcagttc gtgtagcgtt gcggctactt
     1741 actttagcag agtaaatctt cggcaagtgg cggtaaccac tttaccgata ccccagagta
     1801 gtccgcgctt tactggcgtg acccatagtg ccgaaaccgc aaatttcgac actataaagg
     1861 ccttcagcca gggcactaca aaccagacca ccgcagcaca gagacccaca taggccataa
     1921 gaagcaaaat acagagacag gcgctccagt attgcttctg gcaaatatgg tccctggttc
     1981 cgataaccag gcgtttaacg gtggagaaaa tcgtccaaat aaaatggatt tcagtctgga
     2041 atgggaatag aaccgttccc tcggtgtcta acaagttttt catagaaccc tcccgggtaa
     2101 gtatttacaa aagtaactgt cttgattttg gtcatctcaa taacctcgtt tttaagtcaa
     2161 aaggcacccg gcgcctcaca cacgtgaacg ctgttaatgc cgtacagaat gttttatctt
     2221 tcagctctgt tatgatgtgt tcattcgcat cctcctgttt gtcataccga ttttaagctc
     2281 gttccggggg ctccccggaa aaaaatccaa aaaaatccgg gccggaatgg tgataaccag
     2341 tctggcggga aataaacgga tcttgttggg gtggagcggg acggaacaat actatgagag
     2401 taatgttaac agaaatcacc gcctttgtca aggcgcactt atccattaaa gcaactatag
     2461 catagtaata ctgatgtcca tttagcaaaa agtgctatcc gtcgttctgc tgtatgtcta
     2521 ttttccttca cctccgggca acctggcgaa tacattttta ctttttttgc cccctgcccc
     2581 ctcagagtac cgagacgaag agat
//
LOCUS       DAPGUL010000258         2560 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.263, whole genome shotgun sequence.
ACCESSION   DAPGUL010000258 DAPGUL010000000
VERSION     DAPGUL010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2560
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.263"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            211..399
                     /locus_tag="RHX21_004800"
     CDS             211..399
                     /locus_tag="RHX21_004800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FaeA/PapI family transcriptional regulator"
                     /protein_id="HDV1989846.1"
                     /translation="MKDNILTFLTELKTPCRTTEIAIHFGLSAYQARYYLMNLEKEGK
                     IKRSPVRRGASTLWEMNS"
     gene            complement(494..2065)
                     /locus_tag="RHX21_004801"
     CDS             complement(494..2065)
                     /locus_tag="RHX21_004801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HDV1989847.1"
                     /translation="MRQSGVHQISSGNLLKQRLAEQEALIHALQEKLSNREREIDHLQ
                     AQLDKLRRMNFGSRSEKVSRRIAQMEADLNRLQKESDTLTGRVYDPAVQRPLRQTRTR
                     KPFPESLPRDEKRLLPAAPCCPNCGGSLSYLGEDTAEQLELMRSAFRVIRTVREKHAC
                     TQCDAIVQAPAPSRPIERGIAGPGLLARVLTSKYAEHTPLYRQSEIYGRQGVELSRSL
                     LSGWVDACCRLLSPLEEALHGYVMTDGKLHADDTPVQVLLPGNKKTKTGRLWAYVRDD
                     RNAGSALAPAVRFAYSPDRKGIHPQTHLACFSGVLQADAYAGFNELYRNGGITEAACW
                     AHARRKIHDVHVRIPSALTEEALEQIGQLYAIEADIRGMPAEQRLAERQRKTKPLLKS
                     LESWLREKMKTLSRHSELAKAFAYALNQWPALTYYANDGWVEIDNNIAENALRAVSLG
                     RKNFLFFGSDHGGERGALLYGLIGTCRLNGIDPEAYLRHILSVLPEWPSSRVDELLLH
                     ISMEVFGECRTTYSL"
BASE COUNT          601 a          679 c          665 g          615 t
ORIGIN      
        1 acaggagggt aaaaatatta ccgggggaaa caaaagcgga cagaaaaatg actgtggaat
       61 tttcttcttc cggcagaaaa taatcgttgt attatatacg tcagctgcca gccctgatgg
      121 ctttacatgg ctgaaattaa caacgacaag agttcgtatg gtttgatata ccatgcacga
      181 tattcaggtc cacacgggaa ttaacagaat atgaaagaca atatactgac gttcctaacg
      241 gagctgaaaa ctccgtgccg gacaacagaa attgccatac attttgggct gagtgcctat
      301 caggccagat attacctgat gaatctcgaa aaggagggaa agataaaacg ctcgccggta
      361 aggagaggtg ccagtacctt atgggaaatg aattcgtgac gggaaaatat ctgtgcctga
      421 aatataaaaa tggtcaacgg ttttcccggg ttgtcagacg atgaaccatg ccatttcgca
      481 ggtgtaagaa ttattacaga gaatacgtcg tccggcactc accgaacacc tccatgctaa
      541 tatgcagcag gagttcatca acacggctgg aaggccattc cggcagtacg ctcaggatat
      601 ggcgcagata cgcttccgga tcgataccgt tcagtcggca ggtgccgatc agcccgtaca
      661 gtagcgctcc ccgctcacca ccatggtcag agccgaagaa caggaagttt ttacgaccca
      721 gactgaccgc ccgcagggca ttttcagcga tgttgttgtc gatttccacc cagccatcgt
      781 tcgcatagta cgtcagtgcc ggccactggt taagtgcgta cgcgaacgcc ttcgccaact
      841 ctgagtgtcg cgacagggtc ttcatctttt cacgcaacca gctttccagg gatttcaaca
      901 gcggtttcgt ttttcgctga cgttcagcaa gccgctgctc tgccggcatt ccccttatat
      961 ccgcctctat ggcgtacaac tgaccgatct gctccagggc ttcttccgtc agtgctgacg
     1021 ggatgcggac gtgcacatcg tggatctttc ggcgggcatg agcccagcag gcagcttccg
     1081 ttatcccacc attgcgatac agctcgttga acccggcgta cgcatccgct tgcagcacac
     1141 cgctgaagca agcaagatga gtctgcggat ggatgccttt tctgtccggg ctgtaagcga
     1201 acctcactgc aggtgccaac gctgacccgg cattgcggtc atcacgaaca tacgcccaca
     1261 accgcccggt cttcgtcttc ttattacccg gcagcagtac ctggaccggg gtatcatcgg
     1321 catggagttt gccgtcagtc atgacatagc catgaagcgc ctcttccagc ggagacagca
     1381 gccggcagca tgcatccacc cagcccgaca gcagtgaacg gctcagctcc acaccttgcc
     1441 ggccgtatat ttctgactgg cgatacagcg gggtgtgctc tgcatacttc gaggtcagca
     1501 cgcgggccag cagccccggt ccggcgatac cccgctcgat gggccgcgaa ggtgcaggtg
     1561 cctgcacgat ggcatcgcac tgagtacagg catgtttttc ccgtaccgtc cggataaccc
     1621 ggaaggcgct acgcatcaac tccagctgtt cggcagtatc ctcgcccaga tagctcagtg
     1681 aaccgccgca gttcgggcag cacggcgccg caggcaacag tcgcttttcg tcacggggta
     1741 gtgattcagg gaacggctta cgggtgcggg tctgacgcaa cggacgctgt actgccgggt
     1801 catacaccct accagtcagc gtatcgctct ctttctgaag ccggttcaga tcggcttcca
     1861 tttgtgcgat acggcgggag actttttcgg aacgactgcc gaagttcatc cggcggagtt
     1921 tatccagctg cgcctgcaga tggtctattt cgcgctcccg gttgctcagc ttttcctgca
     1981 gggcgtggat cagcgcttcc tgttcggcca ggcgctgttt cagcaggttc ccactactta
     2041 tttggtggac accactttgt ctaattcgtc agattctgac cagacggttc aggctgtacg
     2101 cttacgatga ccataagtat gtctcagcac agtcatcgta acgtgctggt taacctggcc
     2161 atggtagcca aatcatcata ctgtatattc tgttgagggc ggcactggtg attgttcaga
     2221 atacggctga tgcgaaaaag tgcaggcagt ttcctttatt ggtgtgatgt acagcttctt
     2281 tacgctctac tcttccgggg aagaagccat gctgtagcgc tttattgtta cttttcctgg
     2341 ctggacactg tatggtctta tatcccccca cgttttgaac ggaaaaaaca gatttaaagt
     2401 tgccagtagt ctgtaagttt ctgcatccca tttccccgca gagagtgttc tcctgcaata
     2461 tgatgaatgg tttcctggaa cagaaaagga actgagtcag aaatggatag agtgattaat
     2521 atgttgtttt gcagaaaata gggataataa caataaactg
//
LOCUS       DAPGUL010000259         2492 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.265, whole genome shotgun sequence.
ACCESSION   DAPGUL010000259 DAPGUL010000000
VERSION     DAPGUL010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2492
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.265"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            137..346
                     /locus_tag="RHX21_004802"
     CDS             137..346
                     /locus_tag="RHX21_004802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001297677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989848.1"
                     /translation="MKLKKLSGFSLGLIALAVGNAYAEQFIQHDEYKHAVAIKDGKVK
                     DIDNALVITTGNGSYGYPLQERVAS"
     gene            463..>2492
                     /locus_tag="RHX21_004803"
     CDS             463..>2492
                     /locus_tag="RHX21_004803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HDV1989849.1"
                     /translation="MQGKNTIVTTGDYSIGLLSQTSGNLNTDTIIRVNSDGSVTPSFS
                     DGDDTFIVTAGNHAVGVLACASPGSARACVSSLDEESTTDTGSNENNAIAKLDMAKGE
                     ITTHGTESYAAYANGTVVKAGDTLDYTNASVTLTDVNITTHGDNAHAIAARQGTVSFN
                     QGEIYTTGPDAAIAKIYNGGTVTLKNTSAVAHQGAGIVLESSINGQEATVDILSGSSL
                     RSANEILYHKNETSNVTITDSEVSSAADVFINNIKGHLTVDATNSKITGSANISTDDN
                     THTYLSLSDNSTWDIKADSTVSNLTVDNSTVYISRADGRDVEPTRLTITENYVGNNGV
                     LHLRTELGDDNSATDKVVINGNTSGTTRVKVTNAGGSGAYTLNGIEIISVEGESNGEF
                     IKDSRIFAGAYEYSLTRGNTEATNKNWYLTNFQATSGGETNSGGSSAPTVAPTPVLRL
                     EAGSYVANLAAANTLFVMRLNDRAGEMRYIDPVTEQERSSRLWLRQIGGHNAWRDSNG
                     QLRTTSHRYVSQLGADLLTGGFTDSDSWRLGVMAGYARDYNSTHSSVSDYRSKGSVRG
                     YCAGLYATWFADDISKKGAYIDAWAQYSWFKNSVKGDELAYESYSAKGATVSLEAGYG
                     FALNKSFGLEAAKYTWIFQPQAQAIWMGVDHNAHTEANGSRIENDANNNIQTR"
BASE COUNT          713 a          516 c          619 g          644 t
ORIGIN      
        1 tttatatatt gtcgctgttt atctatttaa attttttgtg cttttgtttt tgtctttacc
       61 ctccgttttg gtaatctgaa cgcataggtt atttgaccag gaatgtttgt taatccaatg
      121 aatggatggt taatctatga aactgaaaaa actctccggg tttagtttgg gacttattgc
      181 tctggcggtg ggtaatgcat atgctgaaca gtttattcag cacgatgaat ataaacatgc
      241 tgtggcaata aaagatggaa aagtaaaaga tattgataat gcgctagtta taacaacggg
      301 taatggaagt tacgggtatc cgttgcagga gagggtagca agttaaccat taacaatggc
      361 gtcattgtaa caacgggcgg tttatatcct tctgacaata gtcctctaag cacagcatta
      421 acagctagcg caatcgtaag tgaatttggc ggtgctgtta ttttgcaggg taaaaacacg
      481 attgtcacaa cgggggatta ctcaattggt ttgctaagtc aaacgagtgg aaacctgaat
      541 actgacacca taataagagt caactctgac ggttcggtta ccccctcttt ttctgacgga
      601 gatgatacat ttattgttac tgcgggtaat cacgcagtcg gcgttcttgc gtgtgcatct
      661 cccggaagcg cgcgtgcgtg tgtatcttct cttgatgaag aaagtactac cgatacagga
      721 agtaatgaaa ataatgccat agcaaaactg gatatggcaa aaggggagat cacaacccac
      781 ggaacagaaa gttatgccgc gtacgctaat ggcactgtcg tcaaggctgg tgacacgctt
      841 gattatacca atgccagcgt tacattaacc gatgttaata tcaccacgca tggggacaat
      901 gctcatgcca tcgctgcccg ccaggggaca gtttcattta accagggaga aatttataca
      961 acgggtcctg acgccgcgat tgctaaaatt tataatggcg gcacggtgac gctgaaaaat
     1021 acatctgcag tcgcgcatca gggggctgga attgtgctgg agtcttccat aaatggtcag
     1081 gaagcaacgg tagatatttt atctggtagc tcactacggt cagcaaatga aatcctctac
     1141 cataaaaatg agacgagtaa cgtgaccatt acggatagtg aggtatcatc ggctgcagat
     1201 gtttttatca ataatattaa aggtcatttg accgtcgatg caactaattc aaaaataacg
     1261 ggttcagcta atatttcaac agatgataac actcatacct atctgtcgct ttcagataat
     1321 agtacctggg atattaaagc tgactcaacg gtgagcaacc tcacggttga taatagtacg
     1381 gtctatattt cccgggcaga tggacgggat gtcgaaccaa caagattaac aataactgaa
     1441 aattacgttg gtaataatgg cgtattgcat ctcagaactg aattgggtga tgataattca
     1501 gctacggata aagtcgttat taatggaaat acctctggaa caacccgagt taaagttacc
     1561 aatgcaggag gcagcggagc ttacacgtta aatgggatag agattatcag cgttgagggg
     1621 gaatcaaatg gggaatttat taaggattcg aggattttcg ccggtgccta cgaatattca
     1681 ttaacccgag gtaataccga agcgaccaat aaaaactggt atctgactaa cttccaggca
     1741 acgagcggcg gtgaaacaaa ctccggagga agttcagcgc ctactgttgc gcctaccccc
     1801 gtcctgcgcc tcgaagctgg aagttacgtc gccaacctgg cagccgctaa cactcttttt
     1861 gttatgcgtc tgaacgaccg tgcgggtgaa atgcgctaca tcgatcctgt aactgaacag
     1921 gagcgttcaa gccgactttg gctacgtcaa attggcgggc ataatgcctg gcgtgacagc
     1981 aacggacagt tgagaacgac ctcgcatcgc tacgtctcgc agttaggggc cgatctgtta
     2041 accggtggtt ttaccgacag tgacagttgg cgtttgggag tgatggctgg ttatgcccgc
     2101 gactacaact caactcattc cagcgtgtcg gattatcgtt cgaaagggag tgtcagaggc
     2161 tattgcgcag ggctgtatgc cacctggttt gccgatgaca tcagtaaaaa aggcgcatac
     2221 attgacgcct gggcgcaata tagctggttt aaaaactcgg tgaaagggga tgaattagcc
     2281 tatgaatcct atagtgcgaa aggcgcaacc gtctcgctgg aagcgggtta cggctttgcc
     2341 ctgaataaat cctttggtct ggaagcggcg aaatacacgt ggatattcca gccacaggca
     2401 caggctatct ggatgggcgt cgatcataat gcgcacaccg aagccaatgg ctcacgtatt
     2461 gagaatgacg caaataacaa catccagacc cg
//
LOCUS       DAPGUL010000260         2482 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.266, whole genome shotgun sequence.
ACCESSION   DAPGUL010000260 DAPGUL010000000
VERSION     DAPGUL010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2482)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2482)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2482
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.266"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(45..1451)
                     /gene="gndA"
                     /locus_tag="RHX21_004804"
     CDS             complement(45..1451)
                     /gene="gndA"
                     /locus_tag="RHX21_004804"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HDV1989850.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVIA
                     ENPGKKLVPYYTVQEFVESLETPRRILLMVKAGAGTDSAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILKQIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYALLKGGLALSNDELAQT
                     FTEWNEGELSSYLIDITKDIFTKKDEEGKYLVDVILDEAANKGTGKWTSQSSLDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASDEYNWDLDYGEIAKIFRAGCIIRAQFLQKITDAYAQNAGIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFSAAIAYYDSYRSAVLPANLIQAQRDYFGA
                     HTYKRTDKEGIFHTEWLE"
     gene            complement(1597..>2482)
                     /locus_tag="RHX21_004805"
     CDS             complement(1597..>2482)
                     /locus_tag="RHX21_004805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004144157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDV1989851.1"
                     /translation="DVILSSSHAVAKGVLTGPDQLHISYIHSPIRYAWDLQHQYLRES
                     NLHKGFKGLLAKWILHNIRIWDCRTSNGVDHFIANSKFIARRIKKVYGRNADVIYPPV
                     DVERFTLNENKEQYYFTASRFVPYKRIDLIVEAFSHMKDKKLVVIGDGPEMNKIKAKA
                     TSNIEILGYQSNSVMVDYMRNARAFVFAAEEDFGITPVEAQSCGTPVIAYGKGGALET
                     IRPIGVEKATGVFFYNQDVKSIIDSVNFFEQHSDEIILSDCRLNALKFSEQRFKEEIK
                     EYVMNRHAEFLASKSVVY"
BASE COUNT          708 a          580 c          508 g          686 t
ORIGIN      
        1 gttaaaaaat agtcaggcca aatggcctga ctgagtctag atgtttattc caaccactct
       61 gtatggaata taccctcttt atcggtacgc ttataagtat gcgcaccaaa gtaatcacgc
      121 tgagcctgaa tcaggttagc tggcagaact gcggaacggt aactatcgta gtaggcaatt
      181 gcggcagaga acgtcggtac cggaatacca ttctgcacgg cataagccac gacatcacgc
      241 agcgcttgct gatagtcatc agcgatctgt ttgaagtacg gcgccagcaa gaggttagca
      301 atgccagcgt tttgcgcata agcatcagtg atcttttgta ggaactgcgc acgaatgatg
      361 cagccagcgc ggaaaatctt agcgatctca ccgtagtcca gatcccagtt gtattcatca
      421 gaagcggcac gcagctggga gaagccctga gcataggaaa cgattttacc gaggtacaac
      481 gcacgacgaa ctttttcgat aaattctgct ttatcgccgg ccggctgagc ctgcggacca
      541 ctcagcactt tcgaagcagc tacacgctgg tctttaagcg aagagatgta acgagcaaat
      601 acggactcgg tgatcagaga cagaggttcg ccgagatcca gtgagctctg gctggtccac
      661 ttgccggtac ctttgtttgc agcttcatca agaataacat caacgaggta tttaccttct
      721 tcatccttct tggtgaagat atctttggta atgtcgatca ggtaactgct cagttcacct
      781 tcgttccatt cggtgaaggt ttgcgccagc tcatcgtttg aaagagccag accgcctttc
      841 aacagcgcat aagcttcggc aatcagctgc atgtcaccat actcaatgcc gttatgaacc
      901 atcttcacat aatggccagc accgtcagca ccgatatagg tcacacatgg ctcaccgtct
      961 tcagcaactg cagcaatctg cttcagaatc ggagcaacca gctcataggc ttctttctgg
     1021 ccaccaggca tgatggaagg ccctttcaga gcgccctctt caccaccgga aacaccggta
     1081 ccgataaagt taaaaccttc ggcagacagc tcacggttac gacggatggt gtcctggaag
     1141 aaggtgttgc cgccatcaat gatgatgtcg cctttgtcga ggtaaggctt cagggaatcg
     1201 atggcgctgt cggtgccagc ccctgccttc accatcaaca ggatacggcg gggtgtttcg
     1261 agggattcaa caaactcttg tactgtgtaa taaggaacca gtttcttgcc tggattttcg
     1321 gcaatcactt cttcggtctt ttcacgggag cggttgaaaa cggatacggt ataaccgcgg
     1381 ctttcgatat tcagcgcaag gttacgcccc atcacagcca taccgacaac accgatttgt
     1441 tgcttggaca ttacaaactc ctgtatggtg aaatcactgt aaaattacag ggttatatat
     1501 acctatatta gcatataact aacttcacgc atatcatata tgatcaaact catactgtca
     1561 tcaaacaaaa cataattact atttgaattt aaaaaattaa tatacgacag atttagaggc
     1621 taaaaattca gcatgccgat tcataacata ttctttaatc tcttctttaa atctttgctc
     1681 agaaaatttt agagcgttca gacggcagtc agagagaata atttcatcac tatgctgttc
     1741 aaaaaaatta acgctatcga ttattgactt gacatcttga ttatagaaaa agacaccagt
     1801 tgctttttca actccgatgg gtcgtatcgt ttcaagagca ccaccttttc cataagcgat
     1861 tactggcgta ccgcaagatt gagcttctac aggagttatg ccaaaatcct cttctgcagc
     1921 gaaaacaaaa gcccgcgcat ttctcatata gtcgaccata acgctattag attggtagcc
     1981 aagtatttct atatttgatg ttgctttagc ttttatttta ttcatctcag gtccatcacc
     2041 aataacaact agctttttat ccttcatatg actaaatgct tcaactatca aatctatgcg
     2101 tttataagga acaaatctag atgctgtaaa ataatattgt tctttgttct cattgagtgt
     2161 aaatctttca acatctactg gtggatatat aacatcagca ttacgaccat aaactttttt
     2221 aattcttctt gctatgaatt tggagttcgc aataaaatga tcgacaccat tagacgtgcg
     2281 acaatcccaa atgcgtatat tatgcagaat ccatttcgct aacaaccctt taaaaccttt
     2341 gtgcaagtta gattcacgca agtactgatg ctgaagatcc catgcgtatc ttattggtga
     2401 atgaatataa cttatatgta actgatctgg gcctgtgaga acccccttcg ccactgcatg
     2461 ggaacttgaa agaataacat ca
//
LOCUS       DAPGUL010000261         2471 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.267, whole genome shotgun sequence.
ACCESSION   DAPGUL010000261 DAPGUL010000000
VERSION     DAPGUL010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2471
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.267"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(95..1633)
                     /gene="cadC"
                     /locus_tag="RHX21_004806"
     CDS             complement(95..1633)
                     /gene="cadC"
                     /locus_tag="RHX21_004806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylation/transport transcriptional
                     activator CadC"
                     /protein_id="HDV1989852.1"
                     /translation="MQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFAQHS
                     GEVLSRDELIDNVWKRSIVTNHVVTQSISELRKSLKDNDEDSPVYIATVPKRGYKLMV
                     PVIWYSEEEGEEIMLSSPPPIPEAVPATDSPSHSLNIQNTATPPEQSPVKSKRFTTFW
                     VWFFFLLSLGICVALVAFSTLDTRLPMSKSRILLNPRDIDINMVNKSCNSWSSPYQLS
                     YAIGVGNLVATSLNTFSTFMVHDKINYNIDEPSSSGKTLSIAFVNQRQYRAQQCFMSI
                     KLVDNADGSTMLDKRYVITNGNQLAIQNDLLESLSKALNQPWPQRMQETLQQILPHRG
                     ALLTNFYQAHDYLLHGDDKSLNRASELLGEIVQSSPEFTYARAEKALVDIVRHSQHPL
                     DEKQLAALNTEIDNIVTLPELNNLSIIYQIKAVSALVKGKTDESYQAINTGIDLEMSW
                     LNYVLLGKVYEMKGMNREAADAYLTAFNLRPGANTLYWIENGIFQTSVPYVVPYLDKF
                     LASE"
     gene            complement(2382..>2471)
                     /locus_tag="RHX21_004807"
     CDS             complement(2382..>2471)
                     /locus_tag="RHX21_004807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit M"
                     /protein_id="HDV1989853.1"
                     /translation="SAHITFKRLELIDRINDIIARHFPSVLSA"
BASE COUNT          714 a          494 c          530 g          733 t
ORIGIN      
        1 gcggcaaata aattgccgca acatattata ccaacagaaa catacaaaaa ctcaacaaca
       61 aatattcccg agcataaatc aacccgggag ttacttattc tgaagcgaga aatttgtcga
      121 gataaggtac aacataagga acagaagtct ggaatatacc attttcaatc cagtaaaggg
      181 tgtttgcccc tgggcgtaaa ttaaaggcgg tgagatatgc atcagccgct tcccggttca
      241 tccccttcat ttcataaacc ttgccaagca acacataatt tagccaggac atttcaagat
      301 caatgccagt atttatcgcc tggtaagact catctgtttt accttttacc agagcactga
      361 ccgcttttat ttgatatata atggacagat tattcaattc cggcagtgta acaatgttgt
      421 ctatttctgt gttcagtgct gctaattgtt tttcatctaa aggatgttga gaatggcgca
      481 cgatatcaac taatgctttt tctgctctcg cgtaggtaaa ttctggggat gattgaacaa
      541 tctcacctaa taattcactg gcacggttca atgatttatc atcgccatgc agtaaataat
      601 catgtgcctg ataaaaatta gttaataacg caccacgatg aggcaaaatt tgctggagcg
      661 tctcctgcat tcgttgtggc cacggttggt ttaacgcttt tgataaactc tccagtaaat
      721 cattttgaat cgccagctga ttaccgttag tgatgacata acgtttatcc agcatggttg
      781 aaccatctgc attgtctacc aattttatcg acataaagca ttgttgagca cggtattggc
      841 gctgattaac aaacgcaata gataatgttt taccggaact gctcggttca tcaatgttgt
      901 agttgatttt gtcatgcacc ataaaggtgg agaaggtgtt aagtgatgtc gccaccaaat
      961 tacccacgcc tatcgcgtaa gagagctgat acggggaact ccagctgtta caacttttat
     1021 ttaccatatt aatgtcaata tcgcgtggat tgagcaaaat acgcgatttg ctcatcggaa
     1081 gacgtgtatc aagagttgaa aacgctacca gtgctacaca gatacctaac gacaacagga
     1141 aaaaaaacca tacccaaaag gtagtgaatc gtttgctttt aactggggat tgttcaggtg
     1201 gcgttgcggt gttttgaatg ttaagactgt gggagggaga atctgtggca ggaaccgcct
     1261 ctggtatagg gggaggcgaa gatagcatta tttcctctcc ctcttcttcg ctgtaccaga
     1321 taaccggcac cattaattta tagccgcgct ttggtacagt agcgatatag acaggactat
     1381 cttcatcatt atcttttaat gacttacgta gttctgagat actctgcgtc acaacatgat
     1441 tggtgacaat acttctcttc cagacattat cgataagttc atccctgcta agtacttcgc
     1501 cactgtgttg agcaaagaaa accagaagat cgattaatct cggctcaagg gtaagttgac
     1561 gcccattgcg gctaatttgg tttatggacg gagtaacaag ccattcgcca acgcgaacta
     1621 caggttgttg cataatagaa actcattcga aaagggaatg atgcaatgat aattgccaca
     1681 acctattttt accatctata gatgggttta tttacatatt attggtgaat gtaagacgtt
     1741 atttttacca gccataaact tcttgattac atagtattac gaaaggattt tactgagaac
     1801 cagaagtaat attccttacc atcaaaattc atcatctttg ccaaagaaaa atgttcagaa
     1861 aataatccat ggaaaattgt ccggagcgct tactatttta atggattgtt agtctttgca
     1921 tgagcaagcg gactgataca tttctctttg ttctcattca gaaaatctca tcagtcggcg
     1981 ttcagaccgg tgttgtgctt tatggatgcg ttacgctcct gatgacgtca tttgacgttc
     2041 aacaacatca cggggccgca cgacatttca cgtcagttag tgctatcgct caggaacaaa
     2101 ttttcccgaa ttgggatatg cccgcaaatt gctggtgatg aggggagaat ctggttgagt
     2161 tcgggagaat tgatttggag gcagaacgct taaatcgtgg cgtcctgaaa cgaaaaacgg
     2221 acctccgtgg aggtccgttt atatgaattt ggtgccggac tcggaatcga agagtgcttc
     2281 tatcatgttg atattagttt attttgtttg gtttggtgaa atatgtaccc tcttttgtac
     2341 ccgcagtccc ttttgatatc gaaagggaat caaactcggg gtcaggctga gagcacagaa
     2401 ggaaagtgcc tggctattat atcgttaatt ctgtcaatca gctccagcct tttgaaagtg
     2461 atgtgtgcag a
//
LOCUS       DAPGUL010000262         2469 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.268, whole genome shotgun sequence.
ACCESSION   DAPGUL010000262 DAPGUL010000000
VERSION     DAPGUL010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2469
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.268"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            17..169
                     /locus_tag="RHX21_004808"
     CDS             17..169
                     /locus_tag="RHX21_004808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000730027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HDV1989854.1"
                     /translation="MAAPVLATYISGYYGLGVSLFIVTVAFSALLILLVGFDIPGKIY
                     KLSVAK"
     gene            181..1299
                     /locus_tag="RHX21_004809"
     CDS             181..1299
                     /locus_tag="RHX21_004809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418700.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDV1989855.1"
                     /translation="MINYGVVGVGYFGAELARFMNMHDNAKITCVYDPENGENIAREL
                     QCINMSSLDALVSSKLVDCVIVATPNYLHKEPVIKAAKNKKHVFCEKPIALSYEDCVD
                     MVKACKEAGVTFMAGHIMNFFNGVQYARKLIKEGVIGEILSCHTKRNGWENKQERLSW
                     KKMKEQSGGHLYHHIHELDCVQHLLGEIPETVTMIGGNLAHSGPGFGNEDDMLFMTLE
                     FPSGKLATLEWGSAFNWPEHYVIINGTKGSIKIDMQETAGSLRIGGQTKHFLVHETQE
                     EDDDRRKGNMTSEMDGAIAYGHPGKKTPLWLASLIRKETLFLHNILCGAKPEEDYIDL
                     LNGEAAMSAIATADAATLSRSQDRKVKISEIIKHTSVM"
     gene            1342..1467
                     /locus_tag="RHX21_004810"
     CDS             1342..1467
                     /locus_tag="RHX21_004810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001491548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989856.1"
                     /translation="MIKNFIFDNLIILAVPFMIKTSLKTNLIFFFLCVFVPHMAS"
     gene            complement(1520..1777)
                     /locus_tag="RHX21_004811"
     CDS             complement(1520..1777)
                     /locus_tag="RHX21_004811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989857.1"
                     /translation="MVSSSASNVVNCETKQRTQFECIYFSQYWAKGDFIAKRAPIGQW
                     EPYSEESLLGIIVTSVCRIKVAMLKPEPPRDPHIPLMGDFN"
     gene            1767..2003
                     /locus_tag="RHX21_004812"
                     /pseudo
     CDS             1767..2003
                     /locus_tag="RHX21_004812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939276.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            2091..2469
                     /locus_tag="RHX21_004813"
                     /pseudo
     CDS             2091..2469
                     /locus_tag="RHX21_004813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611483.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          747 a          470 c          558 g          694 t
ORIGIN      
        1 aggggcaact ggaggaatgg ccgcacctgt attagctaca tacatttcag gatattatgg
       61 cttaggtgtt tcattattca ttgttacggt tgcattctct gccttattaa ttttgttagt
      121 tggttttgat attccaggta aaatttataa actatccgtg gctaaatgat tggaggcttt
      181 atgattaatt atggcgttgt tggtgttgga tactttggcg ctgaattagc tcgttttatg
      241 aatatgcatg ataatgcaaa aattacatgt gtatacgatc ctgaaaatgg agaaaatatt
      301 gcccgtgaat tgcagtgtat caatatgtca agcttggatg ctttagtctc aagtaaatta
      361 gtcgattgcg tgatcgtagc caccccaaat tatctgcata aagaaccagt aattaaagca
      421 gcaaagaata agaagcatgt tttttgtgaa aaaccaattg cattaagtta tgaagattgt
      481 gtggatatgg tcaaagcgtg taaagaagct ggtgtgacct ttatggccgg gcatattatg
      541 aattttttca atggggttca atatgcacgg aagttaatta aagaaggtgt tatcggcgaa
      601 atattatcat gtcatactaa gagaaatggc tgggaaaaca aacaagagag actttcctgg
      661 aaaaagatga aagaacaatc tggtggacat ctatatcatc atatacatga gttagattgt
      721 gttcagcatt tacttggaga aataccagag acggttacta tgattggtgg aaatttggcc
      781 cattctggtc caggatttgg caatgaagat gatatgttat ttatgacctt ggaattcccg
      841 tcaggaaaac tagcaacctt agagtggggg agtgcattta actggccgga acattatgtc
      901 atcatcaatg gaactaaagg ctctattaaa attgatatgc aagaaacagc agggtcactt
      961 aggattggcg gtcagacaaa gcattttttg gtccatgaaa cacaagaaga agatgatgat
     1021 cgtcggaaag gcaatatgac ctcagaaatg gatggcgcta tagcatatgg tcatccagga
     1081 aaaaaaacac cattatggct tgccagttta ataagaaagg agacgttatt cctccataat
     1141 atcctctgtg gtgcaaaacc tgaagaagat tatattgacc ttctcaatgg tgaggcggcc
     1201 atgtcggcga ttgctactgc tgatgctgcc actctttcaa gatcgcagga caggaaagtg
     1261 aaaatcagtg agatcattaa acatacatca gtaatgtaaa aactatacgc ctcttgattt
     1321 aattcaggag gccttttatg tatgatcaag aattttatct tcgataatct cataatttta
     1381 gcagtgccat ttatgataaa aacatccctt aaaaccaatc taatcttttt cttcctctgt
     1441 gtatttgttc cccatatggc gtcataattt acgctacgta atacgggata gttacgatac
     1501 gcagcgatag cgctaagttt tagttaaaat cccccatcag cgggatatgg ggatctctgg
     1561 gaggttcagg ttttagcatc gcgactttaa tacgacagac gctggtgacg atgatgccaa
     1621 gtagtgactc ttccgaataa ggttcccact gaccaattgg cgcgcgcttc gcaataaaat
     1681 ctcccttcgc ccagtattgg gaaaagtaga tacattcaaa ctgtgtacgc tgtttcgtct
     1741 cacagttcac gacattgctg gccgatgagc tgaccattgg gcctatccgg gctgtcccga
     1801 tggatattac gccgaagtat gtgggaattg ccagcggatt gatgaacgcc ggttccgctg
     1861 tcgccgacat tatttcacct atcgcctttg gcattattat cgacaaaaca ggcaactgga
     1921 gtttaccatt ctacggttcc gtcgcattgc ttgttattgg tatattcctg acgttcttca
     1981 tgcgtccaga taagtcattg taaaagtcga atcagggctg aagtggcaca ctgaatttgg
     2041 ccacctgaac agaggtgata tgctcacctc agaacaacac aggtgctcca atgaaaaaaa
     2101 gaaatttcag cgcagagttt aaacgcgaat ccgctcaact ggttgttgac cagaaataca
     2161 cggtggcaga tgccgcgaaa gctatggatg ttggcctttc cacaatgaca agatgggtca
     2221 aacaactgcg tgatgagcgt cagggcaaaa caccaaaagc ctctccgata acaccagaac
     2281 aaatcgaaat acgtaagctg aggaaaaagc tacaacgcat tgaaatggag aatgaaatat
     2341 taaaaaggct accgcgctct tgatgtcaga ctccctgaac agttctcgat aatcgggaaa
     2401 ctcagagcgc attatcctgt ggtcacactc tgccatgtgt tcggggttca tcgcagcagc
     2461 tacagatac
//
LOCUS       DAPGUL010000263         2421 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.269, whole genome shotgun sequence.
ACCESSION   DAPGUL010000263 DAPGUL010000000
VERSION     DAPGUL010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2421
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.269"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            56..469
                     /gene="hiuH"
                     /locus_tag="RHX21_004814"
     CDS             56..469
                     /gene="hiuH"
                     /locus_tag="RHX21_004814"
                     /EC_number="3.5.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyisourate hydrolase"
                     /protein_id="HDV1989858.1"
                     /translation="MLKRYLVLSVATAAFSLPSLVYAAQQNILSVHILNQQTGKPAAD
                     VTVTLEKKADNGWLQLNTAKTDKDGRIKALWPEQTATTGDYRVVFKTGDYFKKQNLES
                     FFPEIPVEFHINKVNEHYHVPLLLSQYGYSTYRGS"
     gene            578..1582
                     /gene="msrP"
                     /locus_tag="RHX21_004815"
     CDS             578..1582
                     /gene="msrP"
                     /locus_tag="RHX21_004815"
                     /EC_number="1.8.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-methionine-sulfoxide reductase catalytic
                     subunit MsrP"
                     /protein_id="HDV1989859.1"
                     /translation="MKKNQFLKESDVTAESVFFMKRRQVLKALGISAAALSLPHAAHA
                     DLLSWFKGNDRPPAPAGKPLEFSKPAAWQNNLPLTPADKVSGYNNFYEFGLDKADPAA
                     NAGSLKTDPWTLKISGEVAKPLTLDHDDLTRRFPLEERIYRMRCVEAWSMVVPWIGFP
                     LHKLLALAEPTSNAKYVAFETIYAPEQMPGQQDRFIGGGLKYPYVEGLRLDEAMHPLT
                     LMTVGVYGKALPPQNGAPVRLIVPWKYGFKGIKSIVSIKLTRERPPTTWNLAAPDEYG
                     FYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYADQVASLYRGLDLRENF
                     "
     gene            1583..2218
                     /gene="msrQ"
                     /locus_tag="RHX21_004816"
     CDS             1583..2218
                     /gene="msrQ"
                     /locus_tag="RHX21_004816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-methionine-sulfoxide reductase
                     heme-binding subunit MsrQ"
                     /protein_id="HDV1989860.1"
                     /translation="MRLTAKQVTWLKVSLHLAGLLPFLWLVWAINHGGLGADPVKDIQ
                     HFTGRTALKFLLATLLITPLARYAKQPLLIRTRRLLGLWCFAWATLHLTSYALLELGV
                     NNLALLGKELITRPYLTLGIISWVILLALAFTSTQAMQRKLGKHWQQLHNFVYLVAIL
                     APIHYLWSVKIISPQPLIYAGLAVLLLALRYKKLRSLFNRLRKQVHNKLSV"
BASE COUNT          619 a          593 c          573 g          636 t
ORIGIN      
        1 ccctggccgc tttttcgcta tcctcaaaac tcattcacat gacaaggata taaacatgtt
       61 aaagcgttat ttagtactct cggtagcaac ggcagcattt tcattacctt ctttggttta
      121 tgccgcacaa caaaacattc ttagcgtgca cattttgaac cagcaaaccg gaaaacccgc
      181 tgctgacgtg acagtcactc ttgaaaagaa ggcggataac ggctggttac aacttaatac
      241 cgccaaaaca gataaggatg gacgaattaa ggcactgtgg cccgagcaaa ctgcgactac
      301 tggcgattac cgtgtcgtat ttaaaaccgg ggactatttc aagaaacaaa atcttgaaag
      361 tttcttccct gagatccccg ttgaatttca tattaataaa gtgaacgagc attatcatgt
      421 gcctttatta cttagccaat atgggtattc aacctatcgt ggcagttaaa gcataaatat
      481 gtaaaagcag atctctgcta ctgttaggga ggacactccc tgacagatta acagtaaacg
      541 gctcttgctg gctaacgaca aaaaagtgtg atggcttatg aaaaagaatc aatttttaaa
      601 agaatcagat gttacggccg agtcggtatt ctttatgaag cgtcggcagg tgttaaaagc
      661 actgggcatc agcgcagctg cactttcttt gcctcacgct gcgcatgccg atctgcttag
      721 ctggtttaaa gggaacgatc gcccacccgc ccccgccgga aaaccgctgg agttcagcaa
      781 gcctgccgcc tggcaaaata acctgccact gacgccagca gataaagttt ccggctataa
      841 caacttctat gaattcgggc tggataaagc cgatcccgcc gctaatgctg gtagcctgaa
      901 aaccgatcca tggacactga aaatcagcgg cgaagtggca aaaccattga ccctcgatca
      961 cgatgattta acccgtcgct tcccgctgga agagcgtatt tatcgtatgc gctgcgtgga
     1021 agcgtggtcg atggtggtgc cgtggattgg ttttccgctg cacaaattgc tggcgcttgc
     1081 cgaacccacc agcaatgcga agtatgtcgc tttcgaaaca atttatgcac cggaacagat
     1141 gcctggtcag caggaccgct ttatcggcgg cgggctgaaa tatccttatg tcgaaggatt
     1201 gcgtctcgac gaagcaatgc atccgctcac actgatgacc gtgggtgttt atggcaaggc
     1261 gttaccgcca caaaatggcg cgccggtacg actgattgtg ccgtggaaat atggctttaa
     1321 agggattaaa tcgatagtca gtattaagct gacccgcgag cgtccgccaa ccacctggaa
     1381 tctggcagcg cctgacgaat acggttttta cgccaacgtt aatccgcatg ttgatcaccc
     1441 gcgctggtca caggctaccg aacgatttat tggttcaggc ggcatcctcg atgtacagcg
     1501 ccagccaacg ctactgttta atggttacgc cgaccaggtg gcatcgctgt atcgtggcct
     1561 ggatttgcgg gagaatttct gaatgcgtct gacagcaaaa caggtgacat ggctgaaagt
     1621 tagcctgcat cttgccggat tgttgccgtt tctctggctg gtctgggcga tcaatcacgg
     1681 tggactgggt gccgatccgg tgaaagatat tcagcatttt accggtcgca ctgcactgaa
     1741 atttttgctg gcgaccttgt taatcacacc tctggcacgc tacgcaaaac agccgttatt
     1801 gatacgcact cgccgcctgt taggcttatg gtgctttgcc tgggcgacac tgcatttaac
     1861 cagttacgca ttgctggagc tgggcgtgaa taatctggcg ttattaggta aggagttaat
     1921 tacccggcct tatttaacgt taggaattat cagctgggtt attttgcttg ctttagcgtt
     1981 tacttcaacc caggcgatgc agcgaaaact cggcaagcac tggcaacagt tgcataattt
     2041 cgtctatctt gtcgcgatcc tggccccaat acattatctg tggtcagtga agattatttc
     2101 accgcagccg ctcatctacg ctgggctggc tgtactgctt ttagccttac ggtataagaa
     2161 gttgcgttcc ctttttaacc ggttacgcaa gcaggttcac aacaaattat ctgtataact
     2221 tcatattgcc gacaaagtac gcgttatccc tgccggatgc ggcgcgagcg ccctatccgg
     2281 cctacgcaga tcacatcagg ttatgtttcg tttgtcatca acctcaaatc atcaacctaa
     2341 ttcattttat ttcaataaga tagataagta cacctgagaa aactatgctc tcatctccta
     2401 agagttgttg cattttgtca t
//
LOCUS       DAPGUL010000264         2368 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.270, whole genome shotgun sequence.
ACCESSION   DAPGUL010000264 DAPGUL010000000
VERSION     DAPGUL010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2368
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.270"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            39..668
                     /locus_tag="RHX21_004817"
     CDS             39..668
                     /locus_tag="RHX21_004817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001344968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HDV1989861.1"
                     /translation="MCEHLITVVEKYGAAERVHLGKQAGNVGRAVTKLPLMGKSLHKT
                     IERNQVKTAKKLPGPVPALVITAFVARRLLRFRHMLACRRRGLIVLTDRYPQDQIPGA
                     YDGTVFPPNVEGGRFVSWLASQERKAFHWMASHKPDLVIKLNVDLDVACARKPDHKRE
                     SLARKIAITPQLTFGGAQLVDIDANQPLEQVLVDAEKAITDFMTARGYH"
     gene            complement(717..2216)
                     /gene="pitB"
                     /locus_tag="RHX21_004818"
     CDS             complement(717..2216)
                     /gene="pitB"
                     /locus_tag="RHX21_004818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter PitB"
                     /protein_id="HDV1989862.1"
                     /translation="MLNLFVGLDIYTGLLLLLALAFVLFYEAINGFHDTANAVATVIY
                     TRAMQPQLAVVMAAFFNFFGVLLGGLSVAYAIVHMLPTDLLLNMGSTHGLAMVFSMLL
                     AAIIWNLGTWFFGLPASSSHTLIGAIIGIGLTNALLTGSSVMDALNLREVTKIFSSLI
                     VSPIVGLVIAGGLIFLLRRYWSGTKKRDRIHRIPEDRKKKKGKRKPPFWTRIALIVSA
                     AGVAFSHGANDGQKGIGLVMLVLVGIAPAGFVVNMNASGYEITRTRDAVSNFEHYLQQ
                     HPELPQKLIAMEPPLPAASTDGAQVTEFHCHPANTFDAIARVKTMLPGNMESYEPLSV
                     SQRSQLRRIMLCISDTSAKLAKLPGVSKEDQNLLKKLRSDMLSTIEYAPVWIIMAVAL
                     ALGIGTMIGWRRVAMTIGEKIGKRGMTYAQGMAAQMTAAVSIGLASYIGMPVSTTHVL
                     SSAVAGTMVVDGGGLQRKTVTSILMAWVFTLPAAIFLSGGLYWIALQLI"
BASE COUNT          641 a          603 c          572 g          552 t
ORIGIN      
        1 ttgccgttat tggtagcgat ggttcaggca agtcaacggt gtgtgaacat ctcattaccg
       61 ttgtcgaaaa atatggtgct gccgaaagag ttcatttagg aaaacaagcc ggaaatgtcg
      121 gtcgtgcagt gacaaaatta ccgttgatgg gaaaatcctt acataaaaca attgaacgaa
      181 atcaggtgaa aacagcaaaa aaattgccag gaccagttcc ggcgctggta attacagcgt
      241 ttgtcgcccg tcgcttactg cgctttcgtc atatgcttgc ctgtcgtcgt cgcgggttaa
      301 ttgttctaac cgaccgttat cctcaggacc aaattcctgg cgcttacgat ggtacggtgt
      361 tcccacctaa cgttgaaggt ggtcgttttg tctcatggct ggcaagccag gaacgtaaag
      421 cgtttcactg gatggcgagc cataagcctg atctggtcat caaactcaat gtcgatctag
      481 acgtggcctg cgcgcgtaag cctgaccaca aaagggaatc gctggcaaga aagatagcca
      541 taacgccaca gttaaccttt ggtggtgcac aactggttga tatcgatgcc aatcagccac
      601 tggaacaggt gttggttgat gcagaaaaag cgattacgga ttttatgacc gcgcgtggtt
      661 atcactagtc aaaaatggaa atgcccgatc gccaggaccg ggcattttca ggaaggttaa
      721 atcaactgca atgctatcca gtacagccca ccagaaagaa aaattgccgc cggtaaagta
      781 aacacccatg ccatcaggat gctggttacc gttttacgct gtaacccacc gccgtccacc
      841 accatcgtcc ctgctacggc agatgagagt acgtgtgttg tagagacggg catcccaata
      901 taactggcaa ggccgataga cactgccgcc gtcatttgtg ccgccatgcc ttgcgcatac
      961 gtcatgccgc gcttaccaat cttctcaccg atggtcattg ctacacgacg ccagccaatc
     1021 atggtgccaa tgccgagcgc cagtgctacc gccatgatga tccacaccgg agcgtactca
     1081 atggtgctta acatatcgct gcgcagtttt ttcagcaggt tctggtcttc tttactgacg
     1141 cctggcagtt tcgccagctt cgcggaggta tctgagatgc acagcataat gcggcgcagc
     1201 tggctgcgct gactcacgct taacggctcg taactttcca tattgcctgg cagcatcgtt
     1261 ttaacgcgcg caatcgcatc aaaggtattt gccggatgac agtgaaactc tgttacttgc
     1321 gcgccatcag tcgatgccgc aggcaatgga ggttccatcg caatcaactt ctgcggcagt
     1381 tcaggatgct gttgcagata gtgttcgaag ttggagacgg catcgcgagt acgggtaatt
     1441 tcatagccgg acgcgttcat attgacgacg aagccagcag gggcaatccc caccagtacc
     1501 agcatcacca ggccgatccc tttctgcccg tcgttcgcgc cgtgcgaaaa cgccacgccc
     1561 gcagcggaaa caatcagcgc aatacgcgtc cagaatggcg gtttacgttt gccttttttc
     1621 tttttgcgat cttccggaat gcggtgaata cgatcacgct ttttcgtccc gctccagtag
     1681 cgtcgcagca ggaatatcag gcctcccgca atgaccaggc cgacgatagg ggaaacaatc
     1741 agcgaggaga aaattttggt cacttcacgc aggtttaacg catccatcac cgatgagccg
     1801 gttaacagcg cgttggttaa accgatgccg ataatcgcac caatcaaggt gtgcgaactg
     1861 gaggccggta aaccgaagaa ccacgtcccc aggttccata taatcgccgc cagcagcatg
     1921 gaaaagacca tcgccagacc gtgggttgac cccatattca gcaacaaatc ggttggtaac
     1981 atatggacaa tggcataggc aacgctaagt ccgcccaata acacgccaaa aaagttaaaa
     2041 aatgccgcca tcaccacagc aagttgtggt tgcatggcac gagtataaat aacggttgcc
     2101 accgcattcg ccgtgtcatg aaaaccattg attgcttcgt agaacaacac aaatgccaga
     2161 gcaagcaata acaaaagccc tgtgtatata tcaaggccaa caaataaatt tagcatatat
     2221 tagattacgc cattttgaat ttacgaacgg acgcattatc agtgacttta acggcatggg
     2281 caaagtgaaa tatcattttt taacgataaa aagagtgtta tttcttgtgt atcagacaat
     2341 aagcattcat tcaaaacctt tagaaata
//
LOCUS       DAPGUL010000265         2355 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.271, whole genome shotgun sequence.
ACCESSION   DAPGUL010000265 DAPGUL010000000
VERSION     DAPGUL010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2355
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.271"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..2202
                     /locus_tag="RHX21_004819"
     CDS             <1..2202
                     /locus_tag="RHX21_004819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001763881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HDV1989863.1"
                     /translation="FDGRTQRYHYDLTGKLTQSEDEGLITLWHYDASDRITRRTVNGD
                     PAEQWQYDEHGWLTTISHTSDGHRVSVHYGYDDKGRLTGERQTVENPETGEMLWEHET
                     GHAYSEQGLATRQEPDGLPPVEWLTYGSGYLAGMKLGGTPLVEYTRDRLHRETVRSFG
                     SMAGSNAAYELTSTYTLTGQLQSRHLNLPQLDRDYDWNDNGQLIRISGPQESREYRYS
                     DTGRLTGVHTTAANLDIDIPYATDPAGNRLPDPELHPDSTLTAWPDNRIAEDAHYVYR
                     HDEYGRLAEKTDLIPEGVIRMHDERTHHYHYDSQHRLVFYTRIQHGEPQVESRYLYDP
                     LGRRTGKRVWRRERDLTGWMSLSRKPEETWYGWDGDRLTTVQTQQTRIQTVYQPGSFT
                     PLLRIETENGEQAKARHRSLAEVLQEDTGVTLPAELAVMLGRLERELRAGAVSAESEA
                     WLAQCGLTVEQMESQMEAEYIPERRLHLYHCDHRGLPQALISPEGETAWCGEYDEWGN
                     QLNEENPHHLYQPYRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGINLYT
                     YPLAPIRYTDPLGLERVISVYGPPAPDRAGAETPLVLTDMTGGVTIYYDPETGDSMTF
                     DSSNRIDRRSQRGAGDPYTGEVVGCETNESGISAAYGTTKIYTTDTRARWLHGGGSSL
                     RDPYAPRQGWKPTMGCTRAQNEDVDELCKKVTSWMYSHPGERIRYERFKTR"
BASE COUNT          596 a          573 c          761 g          425 t
ORIGIN      
        1 tttgatggca ggacgcaacg ttaccattat gacttgaccg gaaaactcac gcagagtgaa
       61 gatgaggggc ttatcaccct ctggcattac gatgcgtcag accgtatcac ccggcgcacg
      121 gtgaacggcg acccggcgga acagtggcag tatgatgaac acgggtggct aaccaccatc
      181 agccatacca gtgacggcca ccgagtgtcg gtccactacg gctatgacga taaaggccgc
      241 ctgacgggcg aacggcagac ggtggagaac ccggagacgg gggagatgct gtgggagcat
      301 gagacggggc atgcgtacag cgaacagggg ctggcgaccc gtcaggagcc ggacggtctg
      361 ccgccggtgg agtggctgac gtatggcagc ggttatcttg cggggatgaa gctgggcgga
      421 acaccgctgg tcgagtacac gcgggaccgg ctgcaccgtg agacggtgcg cagcttcggc
      481 agcatggcag gcagtaatgc agcatatgaa ctgaccagca catacaccct cacagggcag
      541 ctacagagca ggcacctgaa cctcccgcag cttgaccggg actacgactg gaacgacaac
      601 ggacagctaa tccgcatcag cggcccgcag gagagccggg agtaccgtta cagtgacacg
      661 ggaaggctga cgggcgtcca caccacggcg gcgaacctgg atatcgatat cccgtatgcg
      721 acggacccgg caggaaaccg gctgccggac ccggaactgc acccggacag cacgctcacg
      781 gcgtggccgg ataaccgcat cgcggaagat gcgcactatg tctaccgcca cgatgaatac
      841 ggcaggctgg cggagaagac ggacctcatc ccggaagggg ttatccggat gcacgacgag
      901 cggacccacc actaccatta cgacagccag caccgtctgg tgttctacac gcggatacag
      961 cacggcgaac cacaggtgga gagccggtac ctctatgacc cgctgggccg ccggacggga
     1021 aaacgggtat ggcggcggga gcgtgacctg acggggtgga tgtcgctgtc gcgtaaaccg
     1081 gaggagacct ggtacgggtg ggacggtgac aggctgacca ctgtacagac ccaacagaca
     1141 agaatccaga cggtatacca gccgggaagc ttcacgccgc tcctgagaat cgaaacagag
     1201 aatggcgaac aggcgaaggc gcggcaccgg agcctggcgg aggtgttgca ggaggacacg
     1261 ggggtgacgc ttccggcgga gctggcggtg atgctgggga ggctggagcg ggaactgcgt
     1321 gcgggagcgg tgagtgcgga gagtgaggca tggcttgcgc agtgcgggct gacggtggag
     1381 cagatggaaa gccagatgga ggcggaatac atcccggagc ggaggctgca tctttaccac
     1441 tgtgaccacc ggggactgcc gcaggcgctc atcagcccgg aaggggaaac ggcgtggtgc
     1501 ggggagtatg acgagtgggg gaaccagctt aatgaggaga acccgcatca cctgtaccag
     1561 ccgtaccggc tgccggggca gcagtatgat gaggagtcgg gactgtatta caaccgtcac
     1621 cggtactacg atccgttgca ggggcggtat atcacccagg atccgatagg gttgaagggg
     1681 ggaataaatc tatacacgta tccactggca ccaatacgtt acactgatcc actggggtta
     1741 gaacgagtta taagtgtata tgggcctccc gctccagacc gggcaggtgc tgaaactcct
     1801 cttgttctta ctgatatgac tggaggagtg actatttatt atgatcctga aacaggtgat
     1861 tcaatgactt ttgatagtag caatagaatt gatcgtcgtt ctcaacgtgg tgctggtgat
     1921 ccatatacag gtgaagtcgt tggttgtgag acaaatgaat caggaatatc ggcagcatat
     1981 ggcacaacga agatctatac tacagatact agagcaagat ggctacatgg tgggggatca
     2041 tcgttgcgcg atccttatgc tcctcgacaa ggctggaaac caactatggg atgtacccgt
     2101 gcacagaatg aagatgtaga tgagttgtgt aagaaagtga caagttggat gtattcgcat
     2161 cctggagaga gaattagata tgaacgtttt aagacacgtt aatgcgatta acatgggagt
     2221 gtgcattcta attttggtta ttggatgtgc aaatgctaaa gttcttaaac gatgtatatt
     2281 acccgctcct gatggtggcg tagaaaaact atcaaaaccc aacttacatg gagtaattaa
     2341 aaaagttgat ttgaa
//
LOCUS       DAPGUL010000266         2332 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.272, whole genome shotgun sequence.
ACCESSION   DAPGUL010000266 DAPGUL010000000
VERSION     DAPGUL010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2332
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.272"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            196..714
                     /locus_tag="RHX21_004820"
     CDS             196..714
                     /locus_tag="RHX21_004820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hcp family type VI secretion system effector"
                     /protein_id="HDV1989864.1"
                     /translation="MPTPCYISITGQTQGNITAGAFTADSVGNIYVQGHEDEMLVQEF
                     LHNVTVPTDPQSGQPAGQRAHKPFIFTVALNKAVPLMYNALASGEMLPTTELHWWRTS
                     VEGKQEHYFTTRLTDSTIVDMKLHMPHCQDPAKREFTQLLEVSLAYRKIEWEHVKSGT
                     SGADDWRAPLEA"
     gene            924..>2332
                     /gene="tssI"
                     /locus_tag="RHX21_004821"
     CDS             924..>2332
                     /gene="tssI"
                     /locus_tag="RHX21_004821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HDV1989865.1"
                     /translation="MSTGLRFTLEVDGLPPDAFAVVSFHLNQSLSSLFSLDLSLVSQQ
                     FLSLEFQQILDKMAYLTIWQGDDVQRRVKGMVTWFELGENDKNQMLYSMKVCPPLWRT
                     GLRQNFRIFQNEDIESILGTILQENGVTEWSPLFSEPHPSREFCVQYGETDYDFLCRM
                     AAEEGIFFYEEHAQKSTDQSLVLCDTVRYLPESFEIPWNPNTRTEVSTLCISQFRYSA
                     QIRPSSVVTKDYTFKRPGWAGRFDQEGQYQDYQRTQYEVYDYPGRFKGAHGQNFARWQ
                     MDGWRNNAEVARGTSRSPEIWPGRRIVLTGHPQANLNREWQVVASDLHGEQPQAVPGR
                     RGSGTTLDNHFAVIPADRTWRPQPLLKPLVDGPQSAVVTGPAGEEIFCDEHGRVRVKF
                     NWDRYNPSNQESSCWIRVAQAWAGTGFGNLAIPRVGQEVIVDFLNGDPDQPIIMGRTY
                     HQENRTPGSLPGTKTQMTIR"
BASE COUNT          548 a          619 c          662 g          503 t
ORIGIN      
        1 attaagttat tgctgaataa gagatttaat gattttaaaa atagttttta cgacaaccgt
       61 aaattctagc tcggtttgta tgtaaaaaat actgaaaaat gatgcggttc cgtgaagtga
      121 gctgcatctg cctgtctggg attaacggca ggtcattgta agtagtaatt aaccacgtta
      181 acaaggagtt tacaaatgcc aacaccgtgt tatatctcca tcactggtca gacccaggga
      241 aatattactg caggtgcatt taccgctgat tctgtcggca acatctatgt gcaggggcac
      301 gaagacgaga tgctggtgca ggaattcctg cataacgtta ctgtcccgac cgatcctcag
      361 tccggtcagc ctgcgggtca gcgtgctcac aagcctttca tttttaccgt ggcgctgaac
      421 aaagcggttc cgctgatgta caacgcactg gcctccggcg aaatgctgcc aaccactgaa
      481 cttcactggt ggcgtacctc tgtggaaggc aaacaggagc attatttcac tacccgcctg
      541 actgattcga cgattgtcga tatgaaactg catatgccgc attgccagga cccggcgaaa
      601 cgcgagttca cccagttgct cgaagtttca ctggcctacc gcaaaattga atgggaacac
      661 gtcaaatctg gcacctccgg tgctgacgac tggcgcgcac cgctggaagc ataagttaag
      721 ccaacagcat ccggctatca ggccggatgc tgtttttgta ttacgccgta gaaagaaagg
      781 ttgtcagtaa ggggttacgt tcacgggaga tggcggctgc cggaaacttc ggcggtagcg
      841 tgcctgaacg caagcgtaac actgtactgt cacagccgct ttaacagcga actgtctgtt
      901 tttccttaac cccggaggtt gctatgtcaa ccggattacg tttcacgctg gaagtggacg
      961 gcctgccacc ggatgctttt gcggtggtct cctttcatct gaaccagtca ctctcttcgc
     1021 ttttttccct cgatctctct ctggtcagcc agcagtttct ctcccttgaa ttccagcaga
     1081 tcctcgacaa aatggcctac ctgacgatat ggcagggcga tgacgtacag cgccgggtga
     1141 aaggtatggt gacctggttt gaactggggg agaacgacaa aaaccagatg ctgtacagca
     1201 tgaaggtgtg cccaccgctg tggcgcacag ggctgcgcca gaacttccgt atcttccaga
     1261 atgaggacat cgaaagcatc ctcggcacga tattgcagga aaacggggtg accgagtgga
     1321 gcccgctgtt cagcgagcca catccttccc gtgagttttg tgtccagtac ggtgagactg
     1381 attacgattt cctgtgccgg atggcggcgg aggaaggcat cttcttttat gaggagcacg
     1441 cgcaaaaaag taccgaccag agcctggtcc tgtgcgatac cgtgcgttat ctgccggagt
     1501 cctttgagat cccctggaat ccgaacaccc gtaccgaggt gagcaccctc tgcatcagcc
     1561 agtttcgcta cagcgcacaa atccgccctt cttccgtggt gaccaaagac tacaccttta
     1621 aacgacccgg ctgggcaggg cgttttgatc aggaaggcca gtaccaggat taccagcgca
     1681 cacagtatga agtgtatgac taccccggac gtttcaaggg tgcccacggg cagaactttg
     1741 cccgctggca gatggatggc tggcgcaaca acgcagaagt ggcgcgcgga acaagccgtt
     1801 cgccggagat atggccggga cggcgaattg tgctgacggg gcatccgcag gcgaacctga
     1861 accgggaatg gcaggtggtg gcgagcgatc ttcacggcga acagccgcag gcggtaccgg
     1921 gacgcagggg ttcaggcacc acgctggata accactttgc ggtaatcccg gcagaccgga
     1981 catggcggcc acagccgttg ctgaaaccgc tggtggacgg cccgcagagc gccgtcgtga
     2041 cgggaccggc aggcgaggaa atcttctgtg atgaacatgg ccgcgtgcgg gtgaaattta
     2101 actgggaccg ctataacccg tcaaaccagg aaagttcatg ctggatccgt gtggcacagg
     2161 cgtgggcagg caccggcttt ggtaacctgg cgataccgcg tgtgggtcag gaggtcattg
     2221 tggacttcct caacggcgat ccggaccagc cgatcattat ggggcgtacc taccaccagg
     2281 aaaaccgcac ccccggcagc ctgccgggga cgaagacgca gatgacgatc cg
//
LOCUS       DAPGUL010000267         2269 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.273, whole genome shotgun sequence.
ACCESSION   DAPGUL010000267 DAPGUL010000000
VERSION     DAPGUL010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2269
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.273"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            28..531
                     /locus_tag="RHX21_004822"
     CDS             28..531
                     /locus_tag="RHX21_004822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313260.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDV1989866.1"
                     /translation="MNNIAPQSPVMRRLTLQDNPAIARVIRQVSAEYGLTADKGYTVA
                     DPNLDELYQVYSQPGHAYWVVEYEGEVVGGGGIAPLAGSESDICELQKMYFLPAIRGK
                     GLAKKLALKAMEEAREMGFKRCYLETTAFLKEAIGLYEHLGFQHIDYALGCTGHVDCE
                     VRMLREL"
     gene            complement(577..993)
                     /gene="rraB"
                     /locus_tag="RHX21_004823"
     CDS             complement(577..993)
                     /gene="rraB"
                     /locus_tag="RHX21_004823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E inhibitor RraB"
                     /protein_id="HDV1989867.1"
                     /translation="MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLE
                     TLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDILSECALNADLIDAQVEQLMTLAE
                     KFDVEYDGWGTYFEDPNGEDGDDEDFVDEDDDGVRH"
     gene            1155..2159
                     /gene="argF"
                     /locus_tag="RHX21_004824"
     CDS             1155..2159
                     /gene="argF"
                     /locus_tag="RHX21_004824"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HDV1989868.1"
                     /translation="MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLT
                     GKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYD
                     GIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKAFNEMTLV
                     YAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTED
                     VAKGVEGADFIYTDVWVSMGEAKEKWAERIALLRDYQVNSKMMQLTGNPEVKFLHCLP
                     AFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSK
                     "
BASE COUNT          580 a          537 c          565 g          587 t
ORIGIN      
        1 attactttat ttttattggg ttaaactatg aataacattg cgccgcaatc acctgtaatg
       61 cgtcgcctga cgctgcagga taatcctgct atcgcccgcg tcattcgtca ggtatccgcc
      121 gaatacggtc ttaccgctga taaaggctac accgtcgccg atccgaatct tgacgagctg
      181 tatcaagtgt atagtcagcc gggtcatgca tattgggtgg ttgagtacga gggtgaagtg
      241 gtcggcggcg gtgggattgc gccattagca ggtagtgaat cggacatttg cgaactgcaa
      301 aagatgtatt ttcttccggc tattcgcggc aaagggctgg caaaaaaact ggccttaaag
      361 gcgatggagg aggcaagaga aatgggcttc aaacgctgct atctggaaac gaccgctttt
      421 ttgaaagaag cgattggttt gtatgaacat ttaggttttc aacatatcga ctatgcactt
      481 ggctgcacgg gccatgttga ttgtgaagtg cggatgttgc gcgaactcta aaaaaatgcc
      541 cgctagtgtg tgctatcggg cattttaatc aattaattag tggcgaaccc cgtcatcgtc
      601 ttcatcgaca aaatcttcat cgtcgccatc ttcgccgttg ggatcttcaa agtaagtgcc
      661 ccaaccgtcg tactcaacgt caaatttctc cgccagcgtc atcagttgtt caacctgggc
      721 atcgatcaga tcggcattca acgcgcactc gctgaggatg tcgcagcaaa tcacgatatc
      781 accatcttca acttccagct cttctggatc ggtcacttcg taaccgagtt taaacgcttc
      841 aactgctgct ttttccaggg tttccagatc gtctgcggaa agatggtgtt cgatggtgta
      901 cagcgcgtcc ggatcgctgc catcttccag taattcttca ataatcaaac gtgtttcttc
      961 acgctgttct tccagttgtt ccgggtttgc catggctcat tcctcttaat gtcctgccga
     1021 tactcatatt gtcacacacc actggcattg cctccacctt tgtgacaaag atttatgctt
     1081 tagacttgca aatgaataat catccatata aattgaattt taattcattg aggcgttagc
     1141 cacaggaggg atctatgtcc gggttttatc ataagcattt cctgaaatta ctcgatttca
     1201 cgccagctga actcaacagc ctgctgcagt tagccgcgaa gctgaaagcc gataagaaaa
     1261 gcggcaaaga agaagccaaa ctcactggta aaaacatcgc gctcatcttc gaaaaagact
     1321 cgacccgtac ccgatgctct ttcgaagttg ccgcatatga ccagggtgct cgcgttactt
     1381 atctcggccc aagcggcagt cagattggtc ataaagagtc gattaaagac actgcccgcg
     1441 tgctgggtcg catgtatgac ggtattcagt atcgcggcta tggtcaggag attgtcgaaa
     1501 cactggcgga atacgctggc gtgccggtat ggaacggcct gaccaatgag tttcacccca
     1561 cgcagttgct ggcggatctc ctcaccatgc aggagcattt acccggtaaa gcattcaacg
     1621 aaatgacgct ggtctatgca ggtgacgcac gtaacaacat gggcaattcg atgctcgaag
     1681 ctgcggcgct taccggtctg gatttgcgtc tggtcgcgcc acaggcatgc tggccggaag
     1741 ctgcgctggt tacggaatgc cgcgctctgg cacagcaaaa tggcgggaat attacgctga
     1801 cggaagatgt agctaaagga gttgaaggtg ctgactttat ctataccgat gtatgggtgt
     1861 cgatgggtga agcaaaagag aaatgggctg aacgcattgc attgctgcgt gattatcaag
     1921 tgaacagcaa gatgatgcag ttgaccggta acccggaggt caaattcctc cactgcctgc
     1981 ccgcgtttca tgacgaccaa acgacgcttg gtaagaaaat ggcggaagag tttggcctac
     2041 atggcggaat ggaagtgact gatgaggtct tcgaatctgc cgccagcatt gtttttgatc
     2101 aggcggaaaa ccgcatgcat accatcaaag cggtgatggt agcgacgctc agtaaataat
     2161 tgatatcgct ataaagatgc cgggaaacac aaaaaacatc ccggcatcac attaatttat
     2221 gcagtgatag ttcaattatt ccaccccaat ttttttattg ctatacgta
//
LOCUS       DAPGUL010000268         2268 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.274, whole genome shotgun sequence.
ACCESSION   DAPGUL010000268 DAPGUL010000000
VERSION     DAPGUL010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2268
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.274"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            497..724
                     /locus_tag="RHX21_004825"
     CDS             497..724
                     /locus_tag="RHX21_004825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989869.1"
                     /translation="MQAAPQREETEWRVQSKRELMPAYRGEAGQQVNIKIMEYSERNV
                     RQLASNEQEEYIPRKINVGVINTPTLIRSDY"
     gene            complement(759..899)
                     /gene="ykgO"
                     /locus_tag="RHX21_004826"
     CDS             complement(759..899)
                     /gene="ykgO"
                     /locus_tag="RHX21_004826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L36"
                     /protein_id="HDV1989870.1"
                     /translation="MKVLNSLRTAKERHPDCQIVKRKGRLYVICKSNPRFKAVQGRKK
                     KR"
     gene            complement(899..1162)
                     /locus_tag="RHX21_004827"
     CDS             complement(899..1162)
                     /locus_tag="RHX21_004827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HDV1989871.1"
                     /translation="MKPNIHPEYRTVVFHDTSVDEYFKIGSTIKTDREIELDGVTYPY
                     VTIDVSSKSHPFYTGKLRTVASEGNVARFTQRFGRFVSTKKGS"
     gene            complement(1525..1626)
                     /locus_tag="RHX21_004828"
     CDS             complement(1525..1626)
                     /locus_tag="RHX21_004828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989872.1"
                     /translation="MKENKVQQISHKLINIVVFVAIVEYAYLFLHFY"
BASE COUNT          657 a          428 c          510 g          673 t
ORIGIN      
        1 aattcttact tgcattttat attggtcagg aactttgccc tgaagtgtta ggaatagtct
       61 taatgcgctg tgtgatggac tagtaaaaaa acaagtttta agggtaaggg atagaatata
      121 aaactataat gagctgtcat tgaagatgat ttgccaatca gtaagaaatt ttaatggatt
      181 aacatgccgc acaaaatggt tataggtgtt cattacaata agtgatggaa aattgaacgg
      241 gcgtatgtac gtcatctgtt cggtaagccc ccaagagcca gattaagtga agttaaacga
      301 aggctgccag ctgtcacagg aacgatggcc tctttgtcag ggcactgagt gcagttatct
      361 gtgcgcgtta ctctaactgg cactcgaacg tcggcgacgg ggttaccggt ggatcagact
      421 gttcctgtgg cgtaaacgtt tttatgttag taccaacaga tttaccacat ttatcatctt
      481 aacagtttga gtgaaaatgc aggctgcgcc gcaaagggag gagactgagt ggcgtgttca
      541 gtctaaaaga gagttgatgc cagcatacag gggcgaagct ggtcaacaag tcaacattaa
      601 gataatggaa tattcggaga gaaacgtcag gcagttggcc tcaaatgaac aggaggaata
      661 tatccccagg aaaattaatg ttggtgttat aaacacacca acattaatcc gatctgatta
      721 ttaatcagac aaatatcgtt aatccgtcga attttgaatc aacgtttttt cttacgaccc
      781 tgaacggcct taaaacgtgg attagattta caaatcacat ataaccgtcc ttttcgcttc
      841 acaatctgac agtctggatg gcgttctttt gcggtacgca gagagttaag aactttcatc
      901 acgacccctt tttcgtgcta acaaaacgac caaaacgttg ggtgaatcgt gcaacatttc
      961 cttctgatgc cactgttctc agcttccctg tatagaacgg gtgcgattta gaagagacat
     1021 caattgtcac gtatggatac gttacgccat ccagctcaat ctcacggtct gttttgatag
     1081 tcgagccgat tttaaagtac tcatcaacac tggtgtcgtg gaacaccaca gtacgatact
     1141 caggatggat attgggcttc atcattttta cctgttatgt tataacataa ccataaagat
     1201 acatgctcat ccggatcatt tcaacaccca atccctgtga ctctttgtgg atgtggaatt
     1261 ttcgcaacgg ggaactctgg cattgttagc agccgttggc gacgctccca taaacgcctg
     1321 gatgagtgat tgatgatggt ttcgctgaga gtatggattt ttcgacaatg gaggttatct
     1381 ccactttact ggccgatgat ttatcgcagt atgattgatt acctgacagc gtgtattcct
     1441 ctcccacgga tataataatt acttacaaaa agggagagga tgcatatttt aaatatcact
     1501 gaagtgaaca gtttattgcc gttattaata gaaatggaga aataaatagg cgtattctac
     1561 aattgcgaca aaaacaacga tattaatcag tttatgactg atttgttgta ctttattctc
     1621 tttcattggt acttcctcgc tttaaaaaag agcgcacttc gtaagtgccc ttatataaat
     1681 aacgagtttg gtcaaccaat tttttgacat gtatcacaaa tttgaatgga tgtattacat
     1741 cggctatctt ttattgcacc aacgtcattg atatatgtcg cctgaagtca gttccgggaa
     1801 tgagtttgat ctcaagactg gcccagtccg ggcgttgatt ggcgctgagg agcatatcgc
     1861 atctcatcat aatgtcgtat ctcctggggt gttatacaag atatcgttgt tggtgacctg
     1921 ggagaggaat tgagttctat taaaccgtca actatgccgg atacatactg gattacactg
     1981 caggcacgcc ttacgagaga acgtgccgca gtgacgggtt aattatctga aagaatttgc
     2041 gaggctgtat cggttactca ttggtttgat agttttactc tcgggagagt aatagatatt
     2101 taattcatta acggaaacca gtcagttcct ttcgatgcct gaatttgatc ccatagttta
     2161 tccggaatgg ttaattcatg aacaagttgt gttatcgttc atgagaagca taacgtaaag
     2221 ggaaaagctc gattagacgg caggatttgt caggggttat gaacgaaa
//
LOCUS       DAPGUL010000269         2265 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.275, whole genome shotgun sequence.
ACCESSION   DAPGUL010000269 DAPGUL010000000
VERSION     DAPGUL010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2265
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.275"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..575)
                     /locus_tag="RHX21_004829"
     CDS             complement(<1..575)
                     /locus_tag="RHX21_004829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraH"
                     /protein_id="HDV1989873.1"
                     /translation="MPRIKPLLVLCAALLTVTPAASADVNSDMNQFFNKLGFASNTTQ
                     PGVWQGQAAGYAYGGSLYARTQVKNVQLISMTLPDINAGCGGIDAYLGSFSFINGEQL
                     QRFVKQIMSNAAGYFFDLALQTTVPEIKTAKDFVQKMASDINSMNLSSCQAAQGIIGG
                     LFPRTQVSQQKVCQDIAGESNIFADWAASRQG"
     gene            complement(575..988)
                     /gene="trbF"
                     /locus_tag="RHX21_004830"
     CDS             complement(575..988)
                     /gene="trbF"
                     /locus_tag="RHX21_004830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001331260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F-type conjugal transfer protein TrbF"
                     /protein_id="HDV1989874.1"
                     /translation="MNHRKYQRELIMRENKSNPELKIRSTERDYKYISRITGRYAGLS
                     LVFLTAGIVLWTVMDIIFDACIDSWKADPELNNSSYMWNILIYAIPYTLYALAAGFLV
                     TFFSVPNVRINIRKYRDIPAEMSYAPGEHIKGGQE"
     gene            complement(942..1283)
                     /gene="trbJ"
                     /locus_tag="RHX21_004831"
     CDS             complement(942..1283)
                     /gene="trbJ"
                     /locus_tag="RHX21_004831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009424419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein TrbJ"
                     /protein_id="HDV1989875.1"
                     /translation="MPPVLWRGWIPFCRCTEEKKVRNKQVVLLIAGISGIVTGIIVSL
                     NIPFIRQGLFYPASPVEIVVSLSLTFSVSVVFFVGAIVGWISVSEIYYSRMTGLNESS
                     EISEGTYNERK"
     gene            complement(1213..1758)
                     /gene="trbB"
                     /locus_tag="RHX21_004832"
     CDS             complement(1213..1758)
                     /gene="trbB"
                     /locus_tag="RHX21_004832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000052622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly thiol-disulfide isomerase TrbB"
                     /protein_id="HDV1989876.1"
                     /translation="MSLTKSLLFTLLLSAAAVQASTRDEIERLWNPQGMATQPAQPAA
                     GTSARTAKPAPRWFRLSNGRQVNLADWKVVLFMQGHCPYCHQFDPVLKQLAQQYGFSV
                     FSYTLDGQGDTAFPEALPVPPEVMQTFFPNIPVATPTTFLVNVNTLEALPLLQGATDA
                     AGFMARVDTVLQMYGGKKGAK"
     gene            complement(1745..2029)
                     /gene="traQ"
                     /locus_tag="RHX21_004833"
     CDS             complement(1745..2029)
                     /gene="traQ"
                     /locus_tag="RHX21_004833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001617873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     chaperone TraQ"
                     /protein_id="HDV1989877.1"
                     /translation="MISKRRFSLPRLDITGMWVFSLGVWFHIVARLVYSKPWMAFFLA
                     ELIAAILVLFGAYQVLDAWIARVSREEREALEARQQAMMEGQQEGGHVSH"
BASE COUNT          616 a          586 c          522 g          541 t
ORIGIN      
        1 ccctgccggg aagccgccca gtcagcaaaa atattgctct caccggcaat gtcctgacag
       61 actttctgct gggacacctg cgtccggggg aaaagcccgc cgataatccc ctgtgcagcc
      121 tggcaggaac tgaggttcat actgttaatg tcgcttgcca ttttctgcac gaagtctttt
      181 gcggttttta tttccggcac cgttgtctgc agggcaaggt caaaaaagta accggcagca
      241 ttgctcataa tctgcttaac aaaacgctgc aactgctcac cattaataaa actgaacgag
      301 ccgagatagg cgtcgatgcc gccacatcca gcattgatat ccggcagcgt catggaaatt
      361 agctgaacat ttttgacctg agtacgggca tacagggagc caccgtaagc atagccggcg
      421 gcctgcccct gccagacgcc cggctgtgtg gtattggaag caaatcccag cttattaaag
      481 aactgattca tgtcgctgtt cacatccgct gacgctgcag gcgtcaccgt cagtaaggcg
      541 gcacaaagaa ccagaagagg tttaatgcgt ggcatcattc ttgccctccc ttaatgtgtt
      601 ctcccggtgc atacgacatt tcagcaggaa tatctcgata tttccgtata ttaattcgca
      661 cattggggac agaaaaaaat gtaacaagaa acccggctgc aagcgcatat aacgtatacg
      721 gaatggcata tatcaggata ttccacatat aactcgaatt atttaattcc gggtccgctt
      781 tccacgaatc aatacaggca tcaaaaataa tatccataac tgtccataaa acaattccgg
      841 cagtcaggaa taccagagac aacccagcat acctgccagt aattctggaa atgtatttat
      901 aatctcgttc tgtacttctg attttgagct caggattact tttattttct ctcattataa
      961 gttccctctg atatttccga tgattcattc agaccggtca tgcggctgta atatatttca
     1021 gacaccgaaa tccatcccac aattgccccc acaaaaaaca caacagaaac agaaaaggta
     1081 agactcagcg aaacgacaat ttctacaggg ctggcgggat aaaaaagccc ctgacggata
     1141 aaggggatat tcaggctgac gattattccc gtcacgatgc cggatattcc ggcaatgagt
     1201 aacaccacct gcttatttcg cacctttttt tcctccgtac atctgcaaaa cggtatccac
     1261 ccgcgccata aaaccggcgg catccgttgc cccctgtaaa agcggtaatg cctcaagcgt
     1321 gttgacgttg accaggaagg tggtcggtgt ggccaccggg atattcggga agaaggtctg
     1381 catcacctcc ggtggcaccg gtaatgcttc aggaaaggcc gtatccccct gaccatccag
     1441 ggtgtaggaa aaaacggaaa agccgtactg ctgtgccagc tgtttcagta ccgggtcaaa
     1501 ctggtgacag taagggcaat gcccctgcat aaacagcacc accttccagt cggccaggtt
     1561 aacctgcctg ccattactga ggcggaacca gcggggagcc ggctttgctg tcctggctga
     1621 cgtgcctgct gccggttgtg caggctgcgt agccataccc tgcggattcc agagtcgctc
     1681 tatttcatcc cgggtggagg cctgcacagc agcggcgctc agcaacaggg tgaacagcag
     1741 tgatttagtg agagacatgt ccgccctcct gctgcccttc catcatggcc tgttgcctgg
     1801 cttccagtgc ctcacgctct tcccggctga cacgggcaat ccatgcatcc agcacctggt
     1861 atgcgccgaa cagtacgaga atggccgcaa tcagctccgc cagaaaaaaa gccatccagg
     1921 gtttgctgta aacaagacgg gcgacgatat gaaaccagac acccagggaa aatacccaca
     1981 ttcccgtaat atcaagccgg ggtaaagaga atctgcgttt acttatcatg ttaaactccg
     2041 gttattattt acatgagagt attcatgtct gtaatattcg cgtttgtgtg atattaatca
     2101 gaggtacaaa tggaaaagcg atcttttaaa gaaaaactgg aaataatcag aaacataata
     2161 agagagtcgt tactgggaaa tgcggcaatt attgcgctga tatatgcagc atcacattca
     2221 ttaccggtca atgccttccc tgactatctt gtaataagtt tatta
//
LOCUS       DAPGUL010000270         2200 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.276, whole genome shotgun sequence.
ACCESSION   DAPGUL010000270 DAPGUL010000000
VERSION     DAPGUL010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2200
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.276"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            187..2172
                     /gene="yjcS"
                     /locus_tag="RHX21_004834"
     CDS             187..2172
                     /gene="yjcS"
                     /locus_tag="RHX21_004834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418507.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl sulfatase YjcS"
                     /protein_id="HDV1989878.1"
                     /translation="MNNSRLFRLSRIVIALTAASGMMVNTAYATDEAKAATQYTQQVN
                     QNYAKSLPFSDRQDFDDAQRGFIAPLLDEGILRDANGKPYYRGEDYKFDINAPAPETV
                     NPSLWRQSQLNGISGLFKVTDRMYQVRGQDISNITFIEGDTGIIVIDPLVTPPSAKAA
                     LDLYFQNRPQKPIVAVIYTHSHTDHYGGVKGIISEADVKSGKVQVIAPAGFMDEAISE
                     NVLAGNIMSRRALYSYGLLLAHNPQGNIGNGLGVTLASGYPSIIAPNKTITKTGEKMI
                     IDGLEFDFLMTPGSEAPAEMHFYIPALKALCTAENATHTLHNFYTLRGAKTRDTSKWT
                     EYLNETLDMWGNDAEVLFMPHTWPVWGNKHINDYIGKYRDTIKYIHDQTLHLANQGYT
                     MNEIGDMIKLPPALANNWASRGYYGSVSHNARAVYNFYLGYYDGNPANLHPYGQVEMG
                     KRYVQALGGSARVINLAQEANKQGDYRWSAELLKQVIAANPGDQVAKNLQANNFEQLG
                     YQAESATWRGFYLTGAKELREGVHKFSHGTTGSPDTIRGMSVEMLFDFMSVRLDSAKA
                     AGKNISLNFNMSNGDNLNLTLNDSVLNYRKTLQPQADASFYISREDLHAVLTGQAKMA
                     DLVKAKKAKIIGNGAKLEEIIACLDNFDLWVNIVTPN"
BASE COUNT          589 a          577 c          535 g          499 t
ORIGIN      
        1 tatttacaga gataataaat tcgcgtaatt ttcccccttc agcacaaatg cctaataaaa
       61 tggatcgttc cgctcacact tccacttatt aaagtcgaaa attcccaatt atgataaccc
      121 cagctttaaa tgacgtattt tgcatggatt acatatttac gacataaatg ataaatggag
      181 atttatatga ataactctcg gttattccgt ttgagcagga ttgttattgc gttaactgct
      241 gccagcggca tgatggtaaa taccgcttac gcaacagatg aagcgaaagc cgccactcaa
      301 tatacccaac aggttaatca gaattacgcc aaatcattac cgtttagcga tcgtcaggat
      361 tttgacgacg ctcagcgtgg atttatcgct ccgctgctgg atgaaggtat tctgcgcgat
      421 gctaatggca aaccatatta tcgcggggaa gattataaat ttgatatcaa tgcgcccgcg
      481 cccgaaaccg ttaaccctag cctgtggcgt cagtcgcagt taaacggtat ttccggcctg
      541 tttaaagtca ccgacagaat gtaccaggtt cgcggtcagg atatctccaa catcaccttt
      601 atcgaaggtg ataccgggat tattgtcatc gacccgctgg tgacgccacc gagcgcaaaa
      661 gccgcccttg acctttactt ccaaaatcgc ccgcaaaaac cgattgttgc ggttatttat
      721 acccacagcc ataccgacca ctatggcggc gtgaaaggca ttatctctga agccgatgtg
      781 aaatccggta aagtgcaggt tatcgcccct gctggcttta tggacgaagc catcagcgaa
      841 aacgtactgg cgggtaatat tatgagccgc cgtgcacttt actcctacgg cctgctgctg
      901 gcgcataacc ctcagggtaa catcggcaat ggtcttggcg taacgctggc atcaggctac
      961 ccgagcatca tcgcaccgaa caaaaccatc accaaaaccg gtgagaagat gattatcgac
     1021 ggcctggagt ttgacttcct gatgacccca ggtagcgaag caccagccga aatgcacttc
     1081 tatattccgg ccctgaaagc gctgtgtacc gccgagaacg ccacgcatac cctgcacaac
     1141 ttctacactc tgcgcggcgc gaaaacccgc gacaccagca agtggaccga gtatctgaac
     1201 gaaacgctgg atatgtgggg taacgacgcg gaagtcctgt ttatgccgca cacctggccg
     1261 gtctggggca ataagcatat caatgattat attggtaaat atcgcgatac tatcaagtac
     1321 attcacgacc agaccctgca cctggcgaac cagggctaca ccatgaatga aatcggcgac
     1381 atgattaaac tgccgcctgc acttgccaat aactgggcca gccgtggcta ttacggttct
     1441 gtcagccaca acgcccgcgc ggtgtataac ttctatcttg gctattacga cggtaacccg
     1501 gctaacctgc atccgtatgg tcaggtggag atgggtaaac gttacgtgca ggcgctgggc
     1561 ggttccgcac gcgttattaa cctggcgcaa gaagcgaaca agcaaggtga ttaccgctgg
     1621 tcggcagaac tgctgaaaca ggtgattgcc gccaacccgg gtgaccaggt cgcgaagaat
     1681 ctgcaagcga ataactttga acagctgggc tatcaggccg agtccgccac ctggcgcggt
     1741 ttctacctga ccggcgcgaa agagctgcgc gaaggggtgc ataagttcag ccacggcacc
     1801 accggttccc cggacaccat tcgcgggatg tcggtcgaaa tgctgttcga ctttatgtcc
     1861 gttcgcctcg atagcgcgaa agccgcgggt aaaaatatca gcctgaactt caatatgagc
     1921 aatggcgata acctcaacct gacgctgaac gatagcgtgc ttaactaccg taaaacgctg
     1981 caaccgcaag ctgacgcctc tttctacatc agccgtgaag atctgcacgc cgtgctgacc
     2041 ggacaagcca aaatggcgga tctggtaaaa gcgaagaaag ccaaaattat tggcaatggc
     2101 gcgaaactgg aagaaattat cgcctgtctg gataatttcg atttgtgggt gaatatcgta
     2161 accccaaatt aatgtcactc gcttttgggg gcgctgaagc
//
LOCUS       DAPGUL010000271         2122 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.277, whole genome shotgun sequence.
ACCESSION   DAPGUL010000271 DAPGUL010000000
VERSION     DAPGUL010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2122
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.277"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            93..425
                     /gene="hdeA"
                     /locus_tag="RHX21_004835"
     CDS             93..425
                     /gene="hdeA"
                     /locus_tag="RHX21_004835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-activated periplasmic chaperone HdeA"
                     /protein_id="HDV1989879.1"
                     /translation="MKKVLGVILGGLLLLPVVSNAADAQKAADNKKPVNSWTCEDFLA
                     VDESFQPTAVGFAEALNNKDKPEDAVLDVQGIATVTPAIVQACTQDKQANFKDKVKGE
                     WDKIKKDM"
     gene            541..867
                     /gene="hdeB"
                     /locus_tag="RHX21_004836"
     CDS             541..867
                     /gene="hdeB"
                     /locus_tag="RHX21_004836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417966.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-activated periplasmic chaperone HdeB"
                     /protein_id="HDV1989880.1"
                     /translation="MNISSLRKAFIFMGAVAALSLVNAQSALAANESAKDMTCQEFID
                     LNPKAMTPVAWWMLHEETVYKGGDTVTLNETDLTQIPKVIEYCKKNPQKNLYTFKNQA
                     SNDLPN"
     gene            931..1578
                     /locus_tag="RHX21_004837"
     CDS             931..1578
                     /locus_tag="RHX21_004837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDV1989881.1"
                     /translation="MTAEFIIRLILAAIACGAIGMERQMRGKGAGLRTHVLIGMGSAL
                     FMIVSKYGFADVLSLDHVGLDPSRIAAQVVTGVGFIGAGNILVRNQNIVGLTTAADIW
                     VTAAIGMVIGSGMYELGIYGSVMTLLVLEVFHQLTFRLMNKNYHLQLTLVNGNTVSML
                     DWFKQQKIKTDLVSLQENEDHEVVAIDIQLHATTSIEDLLRLLKGMAGVKGVSIS"
     gene            complement(1620..>2122)
                     /locus_tag="RHX21_004838"
     CDS             complement(1620..>2122)
                     /locus_tag="RHX21_004838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDV1989882.1"
                     /translation="FFTAMKNILSKGNVVHIQNEEEIDVMLHQNAFVIIDTLMNNVFH
                     SNFLTQIERLKPVHVIIFSPFNIKRCLGKVPVTFVPRTITIIDFVALINGSYCSVPEA
                     NVSLSRKQHQVLSCIANQMTTEDILEKLKISLKTFYCHKHNIMMILNLKRINELVRHQ
                     HIDYLV"
BASE COUNT          630 a          412 c          479 g          601 t
ORIGIN      
        1 atcaacatga catatacaga aaaccaggtt ataacctcag tgtcgaaatt gattcgtgac
       61 ggctctttca ctttatagtt gaggatatta cgatgaaaaa agtattaggc gttattcttg
      121 gtggtctgct tcttctgcca gttgtaagca atgcagcgga tgcgcaaaaa gcagctgata
      181 acaaaaaacc ggtcaactcc tggacctgtg aagatttcct ggctgtggac gaatccttcc
      241 agccaactgc agttggtttt gctgaagcgc tgaacaacaa agataaacca gaagatgcgg
      301 ttttagatgt tcagggtatt gcaaccgtaa ccccagctat cgttcaggct tgtactcagg
      361 ataaacaagc caactttaaa gataaagtta aaggcgaatg ggacaaaatt aagaaagata
      421 tgtaattccg ggaatgcgtt acatcgtact tccttgcata ttgaacaggc cggaatatct
      481 tctttaaaag cagctattcc tcctgttcat atataatctc tatattgaat gggttacaaa
      541 atgaatattt catctctccg taaagcgttt atttttatgg gcgctgtagc ggctttgtca
      601 ctggtgaacg cacaatctgc gctggcagcc aatgaatccg ctaaagatat gacctgccag
      661 gaatttattg atctgaatcc aaaagcaatg accccggttg catggtggat gctgcatgaa
      721 gaaacagtat ataaaggtgg cgataccgtt actttaaatg aaaccgatct cactcaaatt
      781 cctaaagtga tcgaatactg taagaaaaac ccgcagaaaa atttgtatac cttcaaaaat
      841 caagcatcta atgacttgcc gaattaatga ggtacaagta aaaaggagta gcaagttgag
      901 ccatcttgct gctccttttt gcatttttat atgacagcag aatttattat acgtcttata
      961 ctcgcggcaa ttgcctgtgg cgctattggc atggaaaggc aaatgcgcgg caaaggagca
     1021 gggttacgca cacatgtatt aattggcatg ggaagcgccc tgtttatgat tgtttcgaaa
     1081 tatggttttg ctgacgtgct gtctttagat cacgtcggac tcgaccccag ccgtattgct
     1141 gctcaggtgg tgacgggcgt cgggtttatc ggtgcaggta acattctcgt tcgtaaccaa
     1201 aatattgtag gtctgacgac ggcagcggat atctgggtga ccgccgccat aggtatggtt
     1261 attggcagcg gtatgtacga actgggtatt tatggttcag tgatgacctt gttggtgctg
     1321 gaagtcttcc atcaattaac cttccgcctg atgaacaaaa attaccattt acagctgaca
     1381 ttagtgaacg gtaatacggt atcaatgctc gactggttta agcagcaaaa aataaaaacg
     1441 gatttagttt cgttgcagga aaatgaagat catgaagtgg tcgccattga tatccagctt
     1501 catgccacaa cgtcgataga agacctgttg cgattattaa aaggtatggc aggggtgaaa
     1561 ggcgtttcaa ttagctaatc tgtgtggcag cgtagccaga ctcaccgtaa gcctgaaatt
     1621 cacaccagat aatcaatatg ctgatggcgt accagctcat tgatccgctt aagattgagg
     1681 atcatcatga tattgtgttt atggcagtag aacgttttta gcgatatttt cagtttctcc
     1741 agaatatctt ccgttgtcat ttgattcgca atgcagctca gaacctgatg ttgcttgcgc
     1801 gaaagtgaca cattcgcttc aggcacagag cagtaactgc cattgatgag tgcgacaaaa
     1861 tcaatgatag tgatagtccg cggaacaaag gtcaccggta ctttccccag acagcgttta
     1921 atattaaagg gggagaaaat aatcacatgg acaggtttta atcgttcaat ttgagtgaga
     1981 aaattagaat gaaatacatt attcattaat gtatcaataa tgacgaaggc attctgatgc
     2041 aacattacgt cgatctcttc ttcgttctgt atatgaacga cattaccttt actcagaatg
     2101 tttttcatcg cggtgaagaa ca
//
LOCUS       DAPGUL010000272         2118 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.278, whole genome shotgun sequence.
ACCESSION   DAPGUL010000272 DAPGUL010000000
VERSION     DAPGUL010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2118
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.278"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            662..952
                     /locus_tag="RHX21_004839"
     CDS             662..952
                     /locus_tag="RHX21_004839"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989883.1"
                     /translation="MIRKIAEGHISRVSGKVMSAVIRECEDFPPTTVKDIIELLEFYD
                     ETASRVLAGHHRQIPTNNPLLKPWVFGVRFYAYNHFNAKLVTICDLPPTCLF"
     gene            1132..1440
                     /gene="istB"
                     /locus_tag="RHX21_004840"
                     /pseudo
     CDS             1132..1440
                     /gene="istB"
                     /locus_tag="RHX21_004840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016243248.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element IS100kyp family helper ATPase
                     IstB"
     gene            complement(1603..1906)
                     /locus_tag="RHX21_004841"
                     /pseudo
     CDS             complement(1603..1906)
                     /locus_tag="RHX21_004841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001610815.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
BASE COUNT          569 a          545 c          460 g          544 t
ORIGIN      
        1 caaaggttaa aagcaaatca caaccttccc gaacctccgc ttttcgcttg ctacggtccc
       61 tgccgagcat gaatctcgtc tatgcccaaa agcggacatt gataattcag aaaccatggc
      121 agaagtgtgg tatcagcccc tcacctgatg cctgccagca tcgcacctcg cttcatgtct
      181 aacctctctg ttagcccggc agggtcaatg gctctgttga caatggtgct actttccaat
      241 acgttaagca caaggttagc gcgacccggc agctcacggc caaagcggaa tgcagcgcag
      301 acttatcaaa tcttttttgg ttaagtgtct ttgattctta tgattcgtga gcacatagga
      361 cagataagag acttaaacca tgaaacaaat ccccacatgc gctgaagcaa aagcccacgc
      421 caaatacctt tcacggtcgc tcaatatcaa tctaagctac gcccgggatg cagtggcatt
      481 acgttataac taccataact ggtcggaact cagcacagta tttggtcagc ttagctgata
      541 agtacatgtc gtgctatggc cttgccagtc atgaagagaa gcgtgttttt agccagcttc
      601 tggcaccata tatcgcagaa ttgcaaaatg tcattcatcc tgaccgccat gtacggaaag
      661 cttgatacgt aagattgctg aaggccatat ttcccgggta tctggtaaag tcatgtcggc
      721 tgtaatacgt gaatgcgagg attttcctcc cacgacagtt aaagacatca ttgaactgct
      781 tgaattttat gatgaaacgg ccagccgggt attagcagga caccaccggc agatcccgac
      841 caataatccc ttgctgaaac cctgggtatt tggtgtgcgc ttttatgcct ataaccactt
      901 taatgccaag ctggtcacca tctgtgatct tccgccaaca tgcctcttct gaactctccc
      961 gacgtcaaca aaaccccctc taatccctta tatatcagga tttctttgta tccagaggcc
     1021 aaccgccttc accccgtatc aagttacttt tgggggtata atttactctt gaaatatcag
     1081 caccccataa tgaaaaaaat gtgatacata acaacggatt ttaagtaagc gcttcagcgt
     1141 ggagtaatgg ccccccgcct gctcatcatt gatgaaatag gctatctgcc gttcagtcag
     1201 gaagaagcaa agctgttctt ccaggtcatc gctaaacgtt acgaaaaaag cgcaataatc
     1261 ctaacatcca atctgccgtt cgggcagtgg gatcaaacgt tcgccggtga tgcagccctg
     1321 acctcagcga tgctggaccg tatcttacac cactcacatg tcgttcagat aaaaggagaa
     1381 agctatcgac tcagacagaa acgaaaggcc ggggttatag cagaagctaa tcctgagtaa
     1441 cacggtggat caatattggg ccgttggtgg agatataagt ggatcacttt tcatccgtcg
     1501 ttgacacatg catcacaaca gctcctcata agcactcagt ggtcgatgtt ccacctgact
     1561 gatctgctgc cagagcgggg cgtgaggttc cggtactatc tgctagccag acgacactga
     1621 gcagaggcga tgtgaggcca ccagtttctc attactgtag atccgcaact catcgttcag
     1681 cgatattcgt atcgagactg gctgaccaca cagcacttcg ggaacgctgt actgattacc
     1741 tccaacttcg ttatagcggg tcccaggaca catggcggat gtcgaagtaa ctggtatcga
     1801 agtctgtatc cggtaacggc tgcagatgtt cctgctccag cgcgaagcgc tgttccggcg
     1861 tttctttgaa ctgacgaagc tcccatttgt cagccacatc ggctagcgcc agctaaccta
     1921 tgcggtactg gccttggtgc taacccgcgt taaagctacc acgttgatca gagcctctct
     1981 cccggaaagt catactgtct tacatattaa tcactcaaaa tagagtaaat aaaatcatac
     2041 aactagagag tgattataat tgttattgaa cactggttat cccatttttg ttatattgat
     2101 cacaaaaccc ttcttttt
//
LOCUS       DAPGUL010000273         2111 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.279, whole genome shotgun sequence.
ACCESSION   DAPGUL010000273 DAPGUL010000000
VERSION     DAPGUL010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2111)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2111)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2111
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.279"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            247..819
                     /locus_tag="RHX21_004842"
     CDS             247..819
                     /locus_tag="RHX21_004842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001315613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdX family protein"
                     /protein_id="HDV1989884.1"
                     /translation="MASATSENTSSTKNEAQTVLSERSLKAEQRGMEIMDDMQYARLA
                     LFSGDTGAADKLINRAEDLLKSDDKTWETVVRKDKKTPQEGDVYIIINSSLMLSEDFT
                     VTPEKQKAIDEANKKLDKGDKKGAIDVLHLAGIDISETQWLMPLKQTQKKVNSAQKLM
                     SEGKYYEANLALKGAEDGVITDTVSLNEGD"
     gene            975..1709
                     /locus_tag="RHX21_004843"
     CDS             975..1709
                     /locus_tag="RHX21_004843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016232889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDV1989885.1"
                     /translation="MFPYCFAIIVRPFCASFYNEELDFARNEILFLKRNDIQYITDAC
                     EGCVRFIDIPCHIISDYLYIRLRDADALCITDRKNSFFRKKAYGTFLNSLMSLVEQQK
                     NTNLYESVLFVLLDYLNDKNQLLPVLSGGLNNYSLRVEAIVAAEPAKKWYLSDVASAL
                     CISASQLKRKLHSEGAGFSRIITEVRMKKAITLMKCGNANIFIVARECGYSSLSYFIL
                     SFRKYYSVTPCQWLKQYGIKDTTGDG"
BASE COUNT          647 a          355 c          476 g          633 t
ORIGIN      
        1 gtgtgggggt aagtggtcag atttcttata tcagttgcag aacataaaat atgcatgccg
       61 gataggggaa tataaatgtc cgggaggggg acatccttgt ccggcttcct gagtatatga
      121 ctaatcgtca gggggaaaat catattatgt ttattatcag gtatgattct ttctgcctga
      181 tgtcggagta aaaaatatga aacatatctt gtagcaatcg ctctgtccct gacctctgct
      241 gtcgcaatgg cctcagcaac ttcagaaaac acttcatcca caaaaaatga ggctcagaca
      301 gttttatcag aaaggagtct gaaggcagaa cagcgtggta tggaaattat ggatgacatg
      361 cagtatgcac gtcttgcctt attcagtggt gacacaggag cagcagataa gctgataaac
      421 cgggctgaag atttgcttaa atctgatgat aaaacatggg aaacagttgt ccgcaaggat
      481 aaaaaaacac cacaggaagg cgatgtctac attattatta acagcagctt aatgttgtct
      541 gaagacttta ctgtcacccc ggaaaaacag aaagctattg atgaggccaa taaaaaactg
      601 gataaaggtg acaaaaaagg agcaattgac gtactgcatc tcgccggaat tgatatttca
      661 gaaacgcagt ggctgatgcc attaaaacag acgcagaaaa aggttaacag tgcgcaaaaa
      721 ttaatgagcg aagggaaata ctacgaagcc aatcttgcac tgaaaggtgc agaagatggt
      781 gtgattacgg atactgtcag cctgaatgaa ggtgactgat aacatttata tgcgcgtata
      841 accacggtga ccggactgta ttttgtccgg ttactttaat aataaaatcg aacttcttaa
      901 tataatgtca ggaagtaagt ctgtcagcta taataagaaa aataccggat atttctaaat
      961 aacacctgta ctgtatgttt ccgtattgtt ttgccattat agtgaggcca ttctgtgctt
     1021 cattttacaa tgaagagctt gattttgccc ggaatgaaat tctctttctt aaaagaaatg
     1081 acattcagta tattacggat gcctgtgaag gatgtgtgag gtttattgat ataccctgtc
     1141 atatcatcag cgactatctg tatatcagac tgagggatgc cgatgcgtta tgcatcactg
     1201 acaggaaaaa ttcttttttc agaaagaaag cgtatggtac ctttctgaac tcgctgatgt
     1261 cacttgtgga acaacagaaa aatactaacc tttatgagtc agtattattt gtgctgctgg
     1321 attatcttaa tgataaaaac cagttgctgc ctgtattgtc cggtgggctg aataactact
     1381 cgttacgtgt tgaagctatt gttgccgcag agccggcaaa gaaatggtat ctgtcagatg
     1441 ttgcatcagc gttatgtata agtgccagtc agcttaaaag aaaactgcac agtgaaggcg
     1501 caggattcag ccggataatc acagaagtac gtatgaaaaa ggcaataact ctgatgaagt
     1561 gcgggaatgc taacattttt attgtcgcca gagagtgcgg atatagcagt ctgtcgtatt
     1621 ttattttaag tttcagaaaa tactactcag tcactccctg tcagtggtta aaacagtatg
     1681 gtattaagga cacaactggt gacgggtaaa ccctgattca cataaaccgg ttttctggca
     1741 tatacatgct gtacagtcat ccaggcctta taaggggtat attgattttt ttgtgataca
     1801 tttcaatttt ttgttattgt tattgttatt gttattgtta ttgttattgt tattgttatt
     1861 gttatatttt ttaagaaatc ttactcattg tgaaacgatt tttatcgtgc actgtgcttg
     1921 attacatggt tgccagaggt gtctctgtgt aagtgatgtt tctgtatgtt tattgcattg
     1981 agaacaaatg agttatccgg tacagaaaaa aataaaaaca ggtgaaaatg ttctccgggc
     2041 tggtaagcgt caacggagca ccgtattgac gcttatttat tggtgagtac tacgttccat
     2101 ggcaggagtt c
//
LOCUS       DAPGUL010000274         2070 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.280, whole genome shotgun sequence.
ACCESSION   DAPGUL010000274 DAPGUL010000000
VERSION     DAPGUL010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2070
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.280"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..303
                     /gene="radC"
                     /locus_tag="RHX21_004844"
     CDS             <1..303
                     /gene="radC"
                     /locus_tag="RHX21_004844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HDV1989886.1"
                     /translation="FRVLYLNNQNQLIAGETLFTGTINRTEVHPREVIKRALYHNAAA
                     VVLAHNHPSGEVTPSKADRLITERLVQALALVDIRVPDHLIVGGNQVFSFAEHGLL"
     gene            366..587
                     /locus_tag="RHX21_004845"
     CDS             366..587
                     /locus_tag="RHX21_004845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 domain-containing protein"
                     /protein_id="HDV1989887.1"
                     /translation="MKIITRGEAMRIHQQHPASRLFPFCTGKYRWHGSTEAYTGREVQ
                     DIPGVLAVFAERHKDSFGPYVRLMSVTLN"
     gene            750..1124
                     /locus_tag="RHX21_004846"
     CDS             750..1124
                     /locus_tag="RHX21_004846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system YeeU family
                     antitoxin"
                     /protein_id="HDV1989888.1"
                     /translation="MSDKLSGITHPDDNHDRPWWGLPCTVRPCFGARLVQEGNRLHYL
                     ADRAGIRGRFSDADAYHLDQAFPLLMKQLELMLTSGELNPRNQHTVTLYAKGLTCEAD
                     TLGSCGYVYLAVYPAQTPATTS"
     gene            1171..1548
                     /locus_tag="RHX21_004847"
     CDS             1171..1548
                     /locus_tag="RHX21_004847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001683029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin"
                     /protein_id="HDV1989889.1"
                     /translation="MKTLSDTHVREVSRCPSPVTIWQTLLIRLLDQHYGLTLNDTPFA
                     DECVIEQHIEAGISLCDAVNFLVEKYALVRTDQPEFSACTRSQLINSIDILRARRATG
                     LMTRDNYRTVNNITQGKHPEAKQ"
     gene            1545..2033
                     /locus_tag="RHX21_004848"
     CDS             1545..2033
                     /locus_tag="RHX21_004848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989890.1"
                     /translation="MKLTLTLEADSVNVQALNMGRIVVDVDGVNLAELINVVCDNGHS
                     LRVVDESDRVSTDCTPPFAALTGIRCSTAHITAKDNAWLYSLSHQTNDTGESEWIHFT
                     GSGYLLRTDAWSYPVLRLKRLGLSKTFRRLVVTLTRRYGVSLIHLDASAECLPGLPTF
                     DW"
BASE COUNT          490 a          607 c          502 g          471 t
ORIGIN      
        1 ttccgggtgc tgtatctgaa caaccagaat cagctgattg ccggtgaaac cctcttcacc
       61 ggcaccatca accgcacgga agtccatccc cgggaagtga ttaaacgcgc cctgtatcac
      121 aatgccgctg ccgtggtgct ggcacacaat cacccgtccg gtgaagtcac acccagtaag
      181 gcagaccggc ttatcaccga acgtctggta caggcactgg ccctggtgga tatccgggtg
      241 ccggaccatc tgatagtcgg tggcaaccag gttttctcct ttgccgaaca tggtctgctt
      301 taacccgtca caaccacatc acacctgttt tcacttttat cttctgtctt cagaggtatc
      361 ccactatgaa aatcatcacc cgtggtgaag ccatgcgtat tcaccaacaa catccggcat
      421 cccgtctttt tcctttctgt accggcaaat accgctggca cggcagcact gaagcgtata
      481 ccggtcgtga agtgcaggat attcccggtg tgctggccgt gtttgctgaa cgccataagg
      541 acagttttgg cccgtatgtc cggctgatga gcgtcaccct gaactgatgt tccgtcaccc
      601 ggaaaacgag tacgaccaga tggactcaga cgccgctgtg gatgaggcca ttctcgtcaa
      661 tgcatacatc ttcaccgaaa ccggtcagcg cgccggctga cctgtcatcg ttaaaccatt
      721 cttaaccact tttcagagag gattttatcg tgtcagacaa actctccggg ataactcatc
      781 ccgacgacaa tcacgaccgc ccctggtggg ggcttccctg cacagtgagg ccctgttttg
      841 gtgcccgtct ggtgcaggag ggtaaccgcc tgcattacct tgccgaccgc gccggtatca
      901 gaggccgctt cagcgacgca gatgcatacc atctggacca ggcctttccg ctgctgatga
      961 aacaactgga gctcatgctc accagcggtg aactgaatcc ccgaaatcag cataccgtca
     1021 cgctgtatgc aaaagggctg acctgcgaag ccgacaccct cggctcctgt ggttacgttt
     1081 atctggctgt ttatccggca cagacacccg caaccacctc ataaccccga agctctcacc
     1141 tttagcacta ccagttacag agaacttaag atgaaaacat tatccgacac acatgtacgg
     1201 gaggtatctc gctgcccgtc tcccgtcacc atctggcaga cactgctcat ccgactgctg
     1261 gaccagcatt atggcctcac actgaatgac acaccgtttg ccgatgaatg tgtgattgag
     1321 cagcatattg aagctggcat ttcactgtgc gatgcagtga actttcttgt tgaaaaatac
     1381 gcactggtgc gtaccgacca gccggaattc agtgcctgta cccgttctca gttaataaac
     1441 agcatcgata tcctccgggc tcgcagggcg accggcctga tgacccgcga caattacaga
     1501 acggtaaata acattaccca ggggaagcat ccggaggcga aacaatgaaa ctgactctga
     1561 cgctggaagc agacagcgtt aacgtgcagg cgctgaacat gggacgaatt gtcgttgacg
     1621 tcgatggtgt taatctcgct gaactgatta acgtggtctg cgacaatggc cactcccttc
     1681 gtgttgttga tgaatctgac cgggtctcaa cagactgcac gccaccattt gctgccctga
     1741 ccggcatacg ctgcagtacc gcgcatatca ctgcaaagga caacgcctgg ctgtactcgc
     1801 tgtcacatca gacgaatgac accggcgaat cagaatggat tcatttcaca ggtagcggat
     1861 atctgttacg taccgatgcg tggtcatacc cggttctgcg gcttaaacgc ctggggctgt
     1921 caaaaacgtt ccgccgtctg gttgtcacac ttacccgacg ttatggcgtc agtctcattc
     1981 atctggatgc cagcgctgaa tgcctgccgg gtttacccac tttcgactgg taaccagaaa
     2041 caacatgaaa tcattaacca cggaaacagc
//
LOCUS       DAPGUL010000275         2027 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.281, whole genome shotgun sequence.
ACCESSION   DAPGUL010000275 DAPGUL010000000
VERSION     DAPGUL010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2027
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.281"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..1217)
                     /gene="nrfB"
                     /locus_tag="RHX21_004849"
     CDS             complement(<1..1217)
                     /gene="nrfB"
                     /locus_tag="RHX21_004849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage adsorption protein NrfB"
                     /protein_id="HDV1989891.1"
                     /translation="MDWLLDVFATWLYGLKVIAITLAVIMFISGLDDFFIDVVYWVRR
                     IKRKLSVYRRYPRMSYRELYKPDEKPLAIMVPAWNETGVIGNMAELAATTLDYENYHI
                     FVGTYPNDPDTQRDVDEVCARFPNVHKVVCARPGPTSKADCLNNVLDAITQFERSANF
                     AFAGFILHDAEDVISPMELRLFNYLVERKDLIQIPVYPFEREWTHFTSMTYIDEFSEL
                     HGKDVPVREALAGQVPSAGVGTCFSRRAVTALLADGDGIAFDVQSLTEDYDIGFRLKE
                     KGMTEIFVRFPVVDEAKEREQRKFLQHARTSNMICVREYFPDTFSTAVRQKSRWIIGI
                     VFQGFKTHKWTSSLTLNYFLWRDRKGAISNFVSFLAMLVMLQLLLLLAYESLWPNAWH
                     FLSIFSGSAWLMTL"
     gene            complement(1486..>2027)
                     /locus_tag="RHX21_004850"
     CDS             complement(1486..>2027)
                     /locus_tag="RHX21_004850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISAs1-like element ISEc1 family transposase"
                     /protein_id="HDV1989892.1"
                     /translation="GRLNKAFEEKFPLKELNNPEHDSYAISEKSHGREEIRLHIVCDV
                     PDELIDFTFEWKGLKKLCVAVSFRSIIAEQKKEPEMTVRYYISSADLTAEKFATAIRN
                     HWHVENKLHWRLDVVMNEDDCKIRRGNAAELFSGIRHIAINILTNDKVFKAGLRRKMR
                     KAAMDRNYLASVLAGSGLS"
BASE COUNT          522 a          485 c          490 g          530 t
ORIGIN      
        1 agggtcatta accatgcgct gccgctaaaa atagaaagga aatgccaggc attgggccac
       61 aaactttcat acgccagcaa cagcaaaagc tggagcatca ccagcatcgc gaggaagctg
      121 acaaagttac tgattgcccc tttgcggtcg cgccagagaa agtagttcag cgtcaggctg
      181 gaggtccatt tgtgggtttt aaagccctgg aaaacaatgc cgatgatcca gcgagatttt
      241 tgtcgaactg cagtcgaaaa ggtatcgggg aaatattcgc gcacgcagat catgtttgac
      301 gtccgtgcgt gctgtaaaaa tttgcgctgc tcgcgttctt tggcttcgtc caccaccgga
      361 aaacggacaa aaatttccgt catacctttc tctttcaggc ggaaaccaat gtcgtaatct
      421 tcagtcagac tctgcacgtc gaaagcaata ccgtcaccgt cagctaacag agcggtcacg
      481 gcgcggcggc tgaaacaggt gccgacgcct gcgctgggca cttgtccggc gagggcttca
      541 cgcaccggaa catctttgcc atgcagctct gaaaactcat caatgtaagt catgctggtg
      601 aagtgcgtcc attcgcgttc gaacggatac accgggatct gaatcagatc tttacgctcg
      661 accagatagt tgaacagacg caattccatc ggtgaaatca catcttcggc gtcatgcaga
      721 ataaaaccag caaaagcgaa attggcgcta cgttcaaact gggtgatggc gtccagcacg
      781 ttgttcagac agtcggcttt gctggtggga ccaggacgcg cgcagactac cttatgcacg
      841 ttcggaaagc gagcgcacac ttcgtcaaca tcacgttgag tatcggggtc gttggggtag
      901 gtgccaacaa agatatgata gttttcgtag tcgagcgtgg tcgccgccag ctcggccata
      961 ttgccgatga cgcccgtttc attccacgcc ggaaccataa tcgctaacgg tttttcatct
     1021 ggtttataca gttcgcggta actcattcgc gggtagcggc gataaacact caacttgcgt
     1081 ttaatgcggc gtacccagta gacgacatca ataaaaaaat cgtccagccc gctgatgaac
     1141 atgatgaccg ctaacgttat cgcgattact tttaagccgt agagccaggt tgcaaaaaca
     1201 tcaagaagcc agtccacaca aaaaccttac attaacgctg gttatgttta gggtggcgta
     1261 tattaaggtt ttttatgaat tgtgacagct ttttaccatt aataggtatg actattgcgg
     1321 cacgttattt ttacactggt tataaaagtt gccgtttgcg tagaatgtag acaaaagcat
     1381 ggtgtcaagg aggggaggtt aacgtcatag tgaaaaggag cggtggcacc gagcaggtca
     1441 taatgtagtg gaagtgcctg gaggaggtga gcaggcaggg caagattacg aaagcccgct
     1501 ccccgcaagg actgacgcga gatagtttct gtccatggct gcttttcgca tcttacgtct
     1561 taaccctgcc ttgaatacct tatcattcgt taaaatatta atagcgatgt gccgtatccc
     1621 tgaaaataat tctgcggcgt ttcctcttct tattttgcag tcgtcttcat tcattaccac
     1681 gtccagacgc cagtgcagct tattctccac gtgccagtgg tttcggattg ctgtggcgaa
     1741 cttctctgcg gttaaatcag cagaactgat ataatatctg accgtcattt cgggctcttt
     1801 cttttgttct gctattattg accgaaagga gactgccacg cataatttct tcagaccttt
     1861 ccattcaaac gtgaaatcaa taagttcatc agggacatcg caaacaatat gaagacggat
     1921 ttcttctctg ccgtgactct tttcactgat tgcgtaactg tcatgctctg gattatttaa
     1981 ttctttcagc ggaaattttt cctcaaaggc tttatttagc cgcccct
//
LOCUS       DAPGUL010000276         2016 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.282, whole genome shotgun sequence.
ACCESSION   DAPGUL010000276 DAPGUL010000000
VERSION     DAPGUL010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2016
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.282"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            1..2016
                     /locus_tag="RHX21_004851"
                     /pseudo
     CDS             1..2016
                     /locus_tag="RHX21_004851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439272.1"
                     /note="internal stop; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="alpha-amylase family protein"
BASE COUNT          715 a          389 c          372 g          540 t
ORIGIN      
        1 cagagaaatt atatcaactt ttcacgcaga aaaagttatt aatgatctgt taaaaaacga
       61 ttataaaatt tccctttctc cagatacaac ttatcgtgag ttgaataaag cagcacagcg
      121 tagcattaca gcgccagaca ggataggaga aggaaaatca tgggtttatc aaagagatac
      181 aatgattgaa agaggtgata acagcggtgt tcatcagtat ggtcctgctg aacatttcac
      241 ccacattata tctgacaaac cgtccccaaa agatgagtat attgcatatg ctattaacat
      301 tcctgactat gagctggcag ccgatgtata taatattaac gtgacgtcac cttccgaaca
      361 gcaagaaaca tttaaaatac taatcaatcc agaacatcta cggcaaacac ttgagcgtaa
      421 atctcttact gctgttcaga aatcacaatg tgaaatcata acccccaaaa aacctggcga
      481 agcgattctt catgctttta atgccaccta ccagcaaatc agggaaaata tgtctgagtt
      541 tgcacgttgc cattatgggt atatacaaat ccctccagtg acaactttcc gcgccgacgg
      601 accagaaact cccgaagaag aaaagggtta ctggtttcat gcttatcaac ccgaagatct
      661 ttgtaccatc cataatccaa tgggagattt gcaggatttt atcgcattgg ttaaagatgc
      721 taaaaaattt ggtatcgata tcattcctga ttataccttt aactttatgg gaattggggg
      781 tagtggtaaa aatgacctgg attatccctc tgctgatata cgagcgaaga tcagtaaaga
      841 tatagaaggt ggtatccctg gctattggca aggtcaggtt ttgattccat tcattaaaga
      901 tccagtaaca aaagaacgta aacaaatcca tccagaagat atacatctca ctgcaaaaga
      961 cttcgaagca agtaaagata acatatctaa ggatgaatgg gaaaacctcc atgcattaaa
     1021 agaaaagcgt ttaaatggaa tgcctaaaac aacacccaaa agtgaccagg ttattatgtt
     1081 gcaaaatcaa tacgttcgtg aaatgcgaaa atatggcgta cgaggtttac gttacgatgc
     1141 agcaaaacac tcaaaacatg aacaaataga aagatcaata actccaccgc ttaaaaatta
     1201 taatgagcgg ttacacaata ctaacttatt taacccaaaa tatcataaaa aagccgttat
     1261 gaattacatg gaatatctgg taacttgtca gttggatgaa caacaaatgt catcactgct
     1321 ttatgaaaga gatgatttaa gcgccattga tttttcattg ctcatgaaaa cgataaaagc
     1381 cttttcattt ggtggagatc ttcaaaccct tgcatcaaaa ccggattcca caatctcaag
     1441 tatcccatca gaaagacgga tattgattaa cattaaccac gattttccta acaatggtaa
     1501 tcttttcaat gactttctat ttaaccatca acaagatgaa caattagcaa tggcatatat
     1561 agccgctctg ccgttcagca ggcctttagt ttactgggat ggccaagtat taaaatcaac
     1621 gactgaaatt aaaaattatg atgggtccac gcgtgtcggc ggtgaggcgt agcttaataa
     1681 aggttgctct acctatcagc agctctacaa tgaattccac gcattatata tagataaagc
     1741 aggaatatgg agcgcatttg agggtgtatc tgcaactaaa aacgttctgg cctttagtcg
     1801 tggggattct gtgaacatta atcactctcc tcatgatgga ctagttataa taaataaagg
     1861 aaacgaagaa gttgaaggta cctggcctaa caaattgcaa cctggaatat acaaaaacat
     1921 ggggagtaat agcgttaaca ttattattaa taatacccga aaaattatcc cccctggtaa
     1981 agtatttacg cttagaggcg gaactctaaa tatcaa
//
LOCUS       DAPGUL010000277         2000 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.283, whole genome shotgun sequence.
ACCESSION   DAPGUL010000277 DAPGUL010000000
VERSION     DAPGUL010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2000
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.283"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            136..255
                     /locus_tag="RHX21_004852"
     CDS             136..255
                     /locus_tag="RHX21_004852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001131457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDV1989893.1"
                     /translation="MPHSYAEYHHFIMMSLMSGEHNTLALSLQDESPGLVPVG"
     gene            320..742
                     /locus_tag="RHX21_004853"
                     /pseudo
     CDS             320..742
                     /locus_tag="RHX21_004853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311542.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AIDA repeat-containing protein"
     gene            complement(760..1937)
                     /locus_tag="RHX21_004854"
     CDS             complement(join(760..1679,1679..1937))
                     /locus_tag="RHX21_004854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611881.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDV1989894.1"
                     /translation="MNKKTKRTFTPEFRLECAQLIVDKGYSYRQASEAMNVGSTTLES
                     WVRQLRRERQGITPSATPITPDQQRIRELEKQVRRLEEQNTIFKKGYRALNVRLAERF
                     TIAARLSDSHTVVSLCSALEIHRSSYRYWRKRRDTVNPARVRLCSEIRRAWNQSRGSA
                     GARTLAEMLTQNGVPMSRYRAGRLMKYLNLSSCQPGKHQYKNARQEHTSLPNLLERQF
                     AVPEPDRVWCGDITYLWAGNRWCYLAVVMDLFARRVIGWSLSAHADTALISSALRMTY
                     ETRGQPRDVVFHSDQGSQYTGLKYQQLLWRCRINQSVSRRGNCWDNSPMERFFRSLKT
                     EWVPTNGYAGKDEARQQINDYILNYYNSVRPHHYNGGLTPEESENRYHFYCKTVANIT
                     "
BASE COUNT          473 a          483 c          491 g          553 t
ORIGIN      
        1 tattcatcag aaacgattat gtaaatcatt ttattttgcc aacggcctca ttgtcgaaag
       61 aaaagaatac gcccgtattt cctgaatgga ttgacttttt tatccaacca cacttcagcg
      121 cactgcgttt aaaaaatgcc tcattcttat gcggaatatc atcatttcat catgatgtct
      181 ttgatgagcg gtgaacacaa tacacttgcg ctgtctcttc aggatgaatc ccctggtctg
      241 gtgcctgtgg gctgatgttg cagcaaagct aaggtcgctt aaacgctact cagtattcac
      301 ttttcagagg atgaaattta tgaacaggac cagtccctat tattgtcgcc gctcagtact
      361 ttccttattg atatctgcct tgatatatgc cccgcctggg atgacggcct tcactcctga
      421 tgttattggt gtggtaaacg atgagactgt agatggcagc caaagagtag atgaacgagg
      481 tacaacaaat aacactcata ttatcaacca tggccagcag aatgttcatg gcggggtatc
      541 taatggaagt cttattgaat cgggtggata tcaagatgta ggaagtcata acaattttgt
      601 ggggcaggct aataatacaa ccattaacgg aggaagacag acaattcatg acgggggcat
      661 ttccaccggt acgataatcg acagtggcaa tcaggacgtt tatacaggtg gtatcagcaa
      721 tggaacgaca attaagggtg gtaattcaca ctgtagtggt caagtaatat tggccacggt
      781 tttacagtaa aaatggtatc tgttctctga ctcttccggc gtcagcccac cgttataatg
      841 gtgaggtctg acgctgttgt agtagttcaa tatgtaatca ttaatttgct gccgggcctc
      901 gtccttgcct gcgtaaccat tcgttggcac ccattctgtt ttcagactgc ggaagaagcg
      961 ttccatgggg ctgttatccc agcagtttcc ccgccgactg acgctttgat ttattctgca
     1021 acgccagaga agttgttgat atttaaggcc tgtatactgg cttccctggt cgctatggaa
     1081 cacgacatcc cggggttggc cacgcgtctc ataggtcatc cgcagggcac tgcttatcag
     1141 tgcggtatcg gcatgcgctg acagactcca gccgataacc ctgcgggcaa aaagatccat
     1201 aacaaccgcc agatagcacc agcgatttcc tgcccagaga tacgtaatat ctccacacca
     1261 tacccggtct ggctccggta ctgcgaactg acgctcaagc agattcggca ggctggtatg
     1321 ctcctgacgg gcatttttat actgatgttt tccgggctga caactgctca ggttcagata
     1381 tttcatcaga cgtccggcac ggtaacggct catcgggacg ccgttttgag tcagcatttc
     1441 agccagagtg cgcgcgcccg cagagccccg actttggttc cacgcccggc gtatttcgct
     1501 gcacaacctg actcgtgccg gattaaccgt atcgcgtcgt tttcgccagt accggtaact
     1561 gctgcggtgt atttccagag cagaacacag gctgacaacc gtgtggctgt cacttagtct
     1621 ggcggctatc gtgaaccgtt cagcgagtcg gacattaaga gcgcggtagc cttttttaat
     1681 atcgtatttt gttcctccag acggcgaact tgcttttcca gctcgcggat acgttgctgg
     1741 tctggagtaa tgggtgtggc agagggcgta ataccctggc gctctcgcct gagctggcgt
     1801 acccagctct caagcgtggt tgaaccgaca ttcatcgctt cactggcctg tcgatatgag
     1861 tagcccttat caacaatcag ctgtgcacat tccagcctga actcaggggt gaaggttcgt
     1921 ttggttttct tgttcattaa gtcacctgtt ttgtgttgtg gtgagaatat cacctttcat
     1981 caggtggcca aatttagtgt
//
LOCUS       DAPGUL010000278         1964 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.284, whole genome shotgun sequence.
ACCESSION   DAPGUL010000278 DAPGUL010000000
VERSION     DAPGUL010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1964)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1964)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1964
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.284"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            146..778
                     /locus_tag="RHX21_004855"
     CDS             146..778
                     /locus_tag="RHX21_004855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417323.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDV1989895.1"
                     /translation="MGLCSRYKSLTCNSCSMHCQIMPEESPRLQYCANSCFCMWPEES
                     SYFNRGVVEGILTKNHNARLSGYIFVDFSVSFLRLFLEKDWIDYLASTDMGIVLVSDR
                     NMQSLANYWRKHNSAISAVIYNDDGLDVANEKIRQLFIGRYLSFTRGNTLTQMEFTIM
                     GYMVSGYNPYQIAEVLDMDIRSIYAYKQRIEKRMAGKINELFIRSHSVQH"
     gene            1111..1920
                     /locus_tag="RHX21_004856"
     CDS             1111..1920
                     /locus_tag="RHX21_004856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDV1989896.1"
                     /translation="MYWIINDNIEFWPEHRKLISVHNADLNVVLTTPASRCLSLLLEA
                     FPDVVAQQDFFTRVWEEEGMRVPTNTLYQNISIIRRGFRAVGDTTHSLIATVPRRGFK
                     IHNDINIQNHVINSSTDAHTHNAPPAIKVNAGYKESIGGAKNFNNKILKHIKSYLIML
                     SAFVIGAYSAYWLWNNNQPKPFFKDYKTVAEINGCHFNVTEDTIDGLKEFDKYKTRIL
                     DSGINCKKYPWLYFPLAKSSPGMIVMACNKNYNQHEVAGCLTLSYREVNRD"
BASE COUNT          658 a          347 c          357 g          602 t
ORIGIN      
        1 tgcattttaa aatgtcttaa tcagaattat agcaaataca gattaatcgc aattttttcc
       61 agcaaaatta caaaatcatg gtgtattgac atcatcaatc accaatgaaa ttatgcaatt
      121 atatacggat agggaggttc ttaacatggg gctttgtagt cgttataaaa gtcttacatg
      181 caatagttgc tcaatgcatt gccaaataat gccagaagag tcaccgcgtt tgcagtactg
      241 cgcaaactcg tgtttttgta tgtggcccga agaaagttca tattttaatc gtggtgtggt
      301 agaaggtatc ttaacaaaaa accacaatgc gagattaagc ggatatattt ttgtcgattt
      361 ttcagtaagt tttttacgtc tattccttga aaaagactgg attgactatc ttgcaagtac
      421 tgacatgggg attgttttag tcagcgaccg caatatgcaa tcgttagcta attactggcg
      481 aaaacacaac tcagcaatat ctgctgtcat atataatgat gatggtcttg atgttgccaa
      541 tgaaaagatc agacaactat ttattggtcg ttatttatca tttaccagag gtaacacatt
      601 aactcagatg gaattcacca taatggggta tatggtttct ggttataatc catatcagat
      661 tgctgaagtt ctggatatgg atatccgtag catctacgcg tacaagcaac gaatcgaaaa
      721 gagaatggct ggtaaaataa acgaattatt tattcgttca cattcggtcc aacattgata
      781 ctcaacaatc tgcaagaatc atactctgtt tatacgggca tttatggaaa tgcccgtatt
      841 ttataaatag gccgtcccct caagagtaaa cacatagtat ttaaaaccat cacacgaaaa
      901 attcagaagc attacgaaat atgaacttac aaacaatagt ggcataaatg ttaaccatgt
      961 taatttacat aaagttttac gttgcgacat taaagcctca tttcaatcat catgataaat
     1021 ataaaattaa tatatattta tgccgtaaat accaatatac ttagcaaact atgtgatttc
     1081 catttcgatt gatttagtgt ttattgacgt atgtactgga ttattaacga taatatcgag
     1141 ttctggcctg agcaccgaaa attaatatcg gtacataacg ccgatcttaa cgtcgttctg
     1201 acaacgccag ccagtcgttg tttatcactt ctacttgaag cttttcctga tgtggttgca
     1261 caacaagatt ttttcaccag agtctgggaa gaagaaggta tgcgtgtgcc tactaacacg
     1321 ttatatcaga acatatccat tatcagacgc ggatttcgcg ctgttggtga tactacccac
     1381 tcgcttattg caaccgtacc gagaagagga ttcaagatcc ataatgacat taacatacaa
     1441 aatcatgtaa taaactcatc aacagacgca catacacaca atgccccacc tgccataaaa
     1501 gttaatgcgg gatacaaaga gagcattggt ggcgcaaaga atttcaataa caaaatcctc
     1561 aaacatataa aaagttatct aattatgttg agcgcatttg tcataggcgc atattctgca
     1621 tattggctat ggaataataa tcaaccgaaa ccatttttca aggattacaa gactgttgcg
     1681 gaaattaatg gctgccattt taatgtaaca gaagatacaa ttgatgggtt gaaagagttc
     1741 gataaatata aaacacggat actggattcg gggattaact gtaaaaaata tccgtggtta
     1801 tacttccctc ttgcaaaatc ctcaccgggg atgattgtta tggcatgcaa taaaaactat
     1861 aaccaacatg aagtggctgg ctgtttaacc ctgtcttacc gtgaggttaa tcgtgattga
     1921 ttataaaaaa aacttattat ttattttagt ttttatcagt gggt
//
LOCUS       DAPGUL010000279         1912 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.285, whole genome shotgun sequence.
ACCESSION   DAPGUL010000279 DAPGUL010000000
VERSION     DAPGUL010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1912
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.285"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(96..1508)
                     /gene="pykF"
                     /locus_tag="RHX21_004857"
     CDS             complement(96..1508)
                     /gene="pykF"
                     /locus_tag="RHX21_004857"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010346010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase PykF"
                     /protein_id="HDV1989897.1"
                     /translation="MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHG
                     QRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGN
                     SEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNL
                     PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHII
                     SKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVIT
                     ATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICER
                     TDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFP
                     DATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVV
                     MVSGALVPSGTTNTASVHVL"
BASE COUNT          479 a          445 c          466 g          522 t
ORIGIN      
        1 tccgatttga ttttttattg cttctggtta tcgattaaat aaaaaaagcg cccatcaggg
       61 cgcttcgata tacaaattaa ttcacaaaag caatattaca ggacgtgaac agatgcggtg
      121 ttagtagtgc cgctcggtac cagtgcacca gaaaccataa ctacaacgtc acctttgtgt
      181 gccagaccgc tctgcagagc cagttcttta cccagacggt agaaatcatc agtagaagtg
      241 atctctttaa ccagctgcgg cacaacgcct ttgctcagta ccaactgatg agccgttttt
      301 tcgttggtgg tcagtgccag gatggtggca tccgggaagt atttacgtac tgcgcgagca
      361 gatttaccgc cctgagtagc aaccacgatc agcggagcat ccagtttttc agcagtttca
      421 acggcaccac ggcataccgc ttcggtaatg cgcagtttac ggttgtcatt gttgaactcg
      481 agacggctgt tcatcacgcg gtcggtacgt tcgcaaatgg tcgccatgat agaaaccgct
      541 tccagcgggt atttaccttt tgcggattca ccagacagca tcactgcatc agtaccgtcg
      601 aggatggcgt ttgcaacgtc accggcttct gcgcgagtcg ggcgtgggtt tttgatcatg
      661 gaatccagca tctgggtcgc agtgataacg actttacgtg cacggataca tttttcgatc
      721 atcatcttct gggcgaagat aacttcttct accgggattt ctacacccag gtcgccacgc
      781 gcaaccatga tgccgtcaga ggcttcgagg atttcgtcga agttgttgag gccttcctgg
      841 ttttcgattt tggagatgat gtggatgttt tcgccgccgt gcgctttcag gtgctcacgg
      901 atttcgataa cgtcagaacg cttacggata aaggaagcag caacaaagtc tacgccttgt
      961 tcgcaaccaa agatcaggtc ctgtttgtct ttttcagcca gtgctggcag agcaatggaa
     1021 acgccaggca ggttcacacc tttgttttcg cccaggtcac cgttgttcag cactttacag
     1081 ataactttgt taccttcaat ggcggtaact tccataccga tcagaccatc gtcaaccagt
     1141 acggtgttgc caactgacag gtcagtagtg aaaccttcat acgttaccgc aaccatttcg
     1201 ctgttgccga taacagattt atcagtggtg aaagtaaagg tctgaccagc tttcagagaa
     1261 acgtcgttac cgccttccag tttcatggtg cggatttccg gacctttggt atcaagcagg
     1321 atagcggcgg ttttaccagt tttgctcatc acgttgcgca gattctgaat gcgctgaccg
     1381 tgttctgcat agtcaccatg agagaagttc agacgcataa cgttcatgcc agcgtccagc
     1441 attttagcta acatctcttc agattcggtt ttcggtccga tggtgcaaac aattttggtc
     1501 tttttcatga cagtcttagt ctttaagttg agaaggatgg gagaaacttg ctttctgggc
     1561 gcactgccgg aaagcgaatc cggtattacg aaagtggtgg tgcctcgctc taaggatagg
     1621 tgacatcgaa aaagcgtgca gaggaatgtg tgcttgtgtc tcagcccaac gtgagtgcct
     1681 gtttttgagt cgttgagttc tacagtccaa agtgctgaaa ccattcaaga gtcaattggc
     1741 gcgcattata cgctgaaatt aatccaaaag gaaaacaaaa acagcgtttc aaaaaatata
     1801 caacttgtta gacaataaat tgttatcaaa gatttaacgt tccagggaaa aggttacgca
     1861 aaaacttcac tgtttgcgca acgtctggtg ccgaagttgt cagtgtgagg at
//
LOCUS       DAPGUL010000280         1899 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.286, whole genome shotgun sequence.
ACCESSION   DAPGUL010000280 DAPGUL010000000
VERSION     DAPGUL010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1899
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.286"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            1..1360
                     /locus_tag="RHX21_004858"
                     /pseudo
     CDS             1..1360
                     /locus_tag="RHX21_004858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080172.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS66-like element ISEc43 family transposase"
     gene            1490..1762
                     /locus_tag="RHX21_004859"
     CDS             1490..1762
                     /locus_tag="RHX21_004859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001322642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDV1989898.1"
                     /translation="MTPSPYPRNNFNTELIQSCMNGEHFSLLIEISPIRSKKNIMALK
                     EYLVDGYSKQESCERNNVSISYFCLCLKKLNYAHSIVSALKYFYRE"
BASE COUNT          525 a          445 c          477 g          452 t
ORIGIN      
        1 aacaggctga agccctgctg aaacaacgtg aacaggacag cgatcgttac agtgggcggg
       61 aagacgatcc tcaggttccc cgccagttgc gacagtcgcg ccatcgtcgt ccgttaccgg
      121 cacaccttcc ccgtgaaata taccgcctgg agcctgaaga aagctgttgc ccggagtgtg
      181 gcggtgagct tgattatctg ggggaagtca gcgcagaaca actggaactg gtgagcagcg
      241 ccctgaaagt gatccgcaca gaacgggtaa aaaaagcctg tacaaaatgt gactgcatcg
      301 ttgaagcacc ggcaccatcc cgtccgatag agcgtggtat cgcgggcccg gggttacttg
      361 cccgcgtgtt aacgggaaaa tactgcgaac acctgccact gtatcgtcag agtgaaatct
      421 ttgcccgcca gggtgtcgaa ctgagccgtg ccttactctc caactgggtt gatgcgtgct
      481 gccagttaat gacgccgctg aatgatgccc tgtacagtta tgtgatgaac acccgcaagg
      541 ttcacactga tgacacacca gtaaaagtac tggcaccggg caggaagaag gcgaaaacag
      601 gatatatctg gacgtatgtc cgggatgacc gaaatgccgg ttcgccagaa cctccggcgg
      661 tctggttcgc ctactcaccg gaccatcagg gtaaacatcc ggagcaacac cttcgtccct
      721 tccgggtatc ctgcaggcag atgcgttcgc aggttacgat cggctgttca gtgccgaacg
      781 tgaaggcggc gcgttgacgg aagcaggatg ctgggctcat gcgcggcgca aaatccacga
      841 tgtatatatc agtaccaaaa gcgcgacggc ggaagaagca ctgaaactaa tcggcgaact
      901 gtacgccatt gagcacgaaa tacgcgggtt gccggtgtct gaacgcctgg cggtcaggca
      961 aatgcagagt aaaccgctac tgacttccct gtataagctg atgcaggaga aagaacacac
     1021 gttatcgaaa aaatgccgtc tgagagatgc gttccggtat atcaggaagc actgggttgc
     1081 gttgtgcaac ttctgtgatg acggtctggc ggaggcggac aataacacag cggaaagagc
     1141 gcttcgtgca gtctgtctcg gaaagaaaaa ttacgtgttc ttcggtagcg atcacggcgg
     1201 cgagcgtggt gcactgttgt acgggctgat cggcacctgc cggttgaatg gtatcgatcc
     1261 ggaagcgtat ctgcgccata tcctgagcgt actgccggaa tggccttcca accgagttga
     1321 cgaactcctg ccatggaacg tagtactcac taataaataa gcgtcaatac ggtgctccgt
     1381 tgacgcttac tataggagcg taaattacct actatcaaat acttactcca atagcatttc
     1441 tgtctattct atttcaattc tttaatagaa aaataaggtt agataatata tgactccctc
     1501 cccctatcca agaaataact ttaatacaga gctaattcaa tcatgtatga atggagaaca
     1561 cttttcactt ttaattgaaa tatcaccaat cagaagtaaa aaaaacatca tggctcttaa
     1621 ggagtatttg gttgatggtt attcaaagca agaaagttgt gaaaggaaca atgtttccat
     1681 tagttatttt tgcctatgcc taaaaaaact aaactatgca cacagtattg ttagtgctct
     1741 taaatatttc taccgtgagt aaactgtaac tgaagtcttg attcttacgc ttagacactg
     1801 ctaagccgtt atggcatagc tgataattta tattgcacta tgtcagctac tgtaagataa
     1861 tataagctat tttaaagaaa actctgtcat tcatcattt
//
LOCUS       DAPGUL010000281         1866 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.287, whole genome shotgun sequence.
ACCESSION   DAPGUL010000281 DAPGUL010000000
VERSION     DAPGUL010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1866
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.287"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            37..>1866
                     /locus_tag="RHX21_004860"
     CDS             37..>1866
                     /locus_tag="RHX21_004860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000880999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase S74"
                     /protein_id="HDV1989899.1"
                     /translation="MLAQTTLNTELYIPDGFVKQTAAPSGYIEGNVVRIYDQVNKPTK
                     ADLGLSNAMLTGAFGLGGSGISTNGKMSDVEILKALRDKGGHFWRGDKPTGSTATIYS
                     HGSGIFSRCGDTWSAINIDYSTAKIKIYAGNDARLNNGTFSVNELYGSANKPSKSDVG
                     LGNVTNDAQVKKSGDVMSGDLTIKKDTPSLFLRAGSGTGAAAVRFYTGDNTERGIIYA
                     GPNTDSLGEVRIRAKTAGGTSGGDLVVRHDGRVEVRDLTVAYKIKSRTIEIANTDTDS
                     SATTLSIYGAQHTPLVLTRSGSSENVSIGFKLDNVNQKYLGIDTNGDLAFGESPDQKQ
                     NSKLITQAKLDKGLTIGGQLAFKGTTAFSAAATFSAGIAGAIEPENIGGQKVDLNNLT
                     IRSDAGAVKYYSCPSSAGGANITNKPDGVTGNFLLRVESTRKVSASDYANMQTLISND
                     TKRIYVRFVVNGNWTAWSQVVVSGWNQDITVRSLTTSSPVKSGGGRIDVLGSTSDYSK
                     MDCFVRGFDSTGNSLAWALGSSAGVSKMLSLKNFFSGAEILLNGNDGTVQLKTGAVNG
                     ATAQALTINRNEVNSTVDLTLTKQSGTGNRFVLQNSGNAELPFS"
BASE COUNT          511 a          400 c          495 g          460 t
ORIGIN      
        1 ttccagggtg cgtttattaa cgacgcaaag gttgcggtgc tggcgcagac aacactaaac
       61 acagaattat acattccaga cggatttgtt aagcaaaccg ccgcgccttc tggatatatt
      121 gaaggcaacg ttgtaaggat ttacgaccag gtaaacaagc cgactaaagc agatttgggt
      181 ctttctaatg ctatgcttac aggcgctttc ggtcttggcg gtagcgggat atcaacaaac
      241 ggcaagatga gcgatgtaga gatcttaaaa gctctgcgtg acaaaggtgg tcatttctgg
      301 cgcggtgata agccgaccgg aagcacggcg accatttata gccacggttc tggtatattc
      361 tcgcggtgcg gcgatacgtg gtcagcgatc aatatcgact actcaaccgc gaagattaag
      421 atctatgccg gcaacgatgc ccggcttaac aacgggactt ttagcgtcaa tgagctatac
      481 ggctcggcaa acaagccgtc gaaatcggat gttggacttg gcaacgtaac taatgatgcg
      541 caggtgaaaa aatccggcga tgttatgtca ggtgacttga cgatcaaaaa agacacgccg
      601 tcactcttcc ttcgggcagg tagtggaact ggtgctgccg ctgtgcggtt ttatactggc
      661 gataacacag agcgcggcat aatctatgct ggtcctaaca ctgattcgct tggcgaagtt
      721 cgcatcaggg caaagacagc aggggggaca tcaggagggg atcttgttgt tcgtcacgac
      781 gggagggttg aagtccgtga tctcacagta gcgtataaaa ttaaaagcag aacgattgag
      841 attgcaaata ccgacactga ctcatcggca actacgctca gcatctatgg agcacagcac
      901 acgccgttgg ttttaacgcg ttctggttct tctgaaaatg tgtccattgg gtttaagtta
      961 gacaacgtga accaaaagta tcttggaatt gatactaatg gggatctggc ttttggcgag
     1021 agtcctgatc agaaacaaaa cagcaaattg atcacgcaag cgaaactcga caagggatta
     1081 acgattggtg gtcaactggc tttcaaaggt acgacagcgt tttcagccgc tgctacgttc
     1141 agtgccggga tagcaggagc tatcgagccg gaaaacattg gcggccagaa ggttgatctt
     1201 aacaacctga ccatcaggtc agatgccggg gcggttaaat actatagttg tccatcctct
     1261 gcaggtggtg caaatatcac caacaagcct gacggtgtaa ccggtaactt tttgctccgt
     1321 gtagagtcga ctcgcaaagt ttctgcttcg gattatgcga acatgcaaac gctgatcagc
     1381 aacgacacaa aacgtatata cgttcgcttt gttgttaatg gaaactggac agcgtggagt
     1441 caggttgttg tttccggatg gaatcaggat ataactgtca ggtcgttaac cacatctagt
     1501 ccggtaaaat ctggcggagg gcgaattgat gtccttggaa gcacgtcaga ctatagcaaa
     1561 atggattgct ttgtacgtgg gtttgatagc accggtaatt ctctcgcgtg ggcgttgggt
     1621 tcatcagccg gcgtaagtaa gatgctgtcg ctaaaaaatt tctttagcgg agctgagata
     1681 ctgttaaatg gtaatgacgg cacggttcaa ctcaaaacag gtgctgttaa cggggctaca
     1741 gcgcaggcgc tcactatcaa caggaatgag gttaactcaa ctgttgattt aacccttaca
     1801 aaacaatcag ggactggcaa tcgttttgtt ttacagaact caggtaatgc agaactaccg
     1861 ttttct
//
LOCUS       DAPGUL010000282         1794 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.288, whole genome shotgun sequence.
ACCESSION   DAPGUL010000282 DAPGUL010000000
VERSION     DAPGUL010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1794)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1794)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1794
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.288"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..1324
                     /locus_tag="RHX21_004861"
     CDS             <1..1324
                     /locus_tag="RHX21_004861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="fimbria/pilus outer membrane usher protein"
                     /protein_id="HDV1989900.1"
                     /translation="LSDNYNAITLGNGWNTPLGAISFYAARSSSKLNNDTRHEGTSYQ
                     VAYNKYLVQTATRFSVAAWRYASQDYRTFSDHLYENDKHYHQSDYDDFYDIGRKNSLS
                     ANIMQPLSNNLGNVSLSALWRNYWGRSGNAKDYQFSYSNNWQHISYTFSASQSYDENN
                     KEEERFNLFISIPFYWGDDIAKTRHQINLSNSTSFSKDGYSSNNTGITGIAGEHDQLN
                     YGIYVNQQQQNNDTSLGTNLSWRTPIAIIDGSYSHSKNAWQSGGSISSGLVVWPGGIN
                     ITNQLSDTFAILDAPGLEGAHINGQKYNRTNSKGQVVYDLIIPHRENHLVLDIANSES
                     ETELQGNRQIIAPYRGAVSYVQFTTDQRKPWYIQALRPDGSPLTFGYDVLDLQENNIG
                     VVGQGSRLFIRVDEIPTGIKVALNDEQNLFCTITFQHVIDENKTYICQ"
     gene            1337..1794
                     /locus_tag="RHX21_004862"
                     /pseudo
     CDS             1337..1794
                     /locus_tag="RHX21_004862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000871680.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial family protein"
BASE COUNT          569 a          351 c          346 g          528 t
ORIGIN      
        1 tttatccgat aactataatg ctataactct gggaaatggt tggaatacac cgctgggtgc
       61 catctctttt tacgctgccc gatcgagtag taagttaaat aatgatacca gacacgaagg
      121 tacgagctat caggtcgcct ataataaata tctagtacaa acagccactc gatttagcgt
      181 ggccgcctgg cgttatgctt cgcaggatta caggacattc agcgaccatc tttacgaaaa
      241 tgataaacac tatcatcaga gtgattatga tgatttttat gatattggca gaaaaaatag
      301 cctttctgct aatattatgc aacctttatc caataatctg ggaaatgtat cattaagtgc
      361 gctttggcgg aattactggg ggcgaagtgg aaatgctaaa gattaccaat tcagttactc
      421 caataactgg caacacatta gttatacttt ctctgccagc caatcttatg atgaaaataa
      481 taaagaagag gagcgtttta atctgtttat ctccattcct ttctactggg gggatgatat
      541 tgccaaaaca cgtcaccaaa ttaacttatc gaattcgacc tcattttcca aagatggcta
      601 ttcctccaac aatactggaa ttactggcat agccggtgaa catgatcagt taaattatgg
      661 tatatatgtt aatcagcaac aacaaaataa tgatacctcg cttggtacga atttaagctg
      721 gagaactccc atcgccataa tagatggcag ctatagtcat tctaaaaacg cctggcaaag
      781 tggtggaagt attagtagtg gattagttgt ctggcccggt ggtattaata tcactaacca
      841 gttatccgat acatttgcaa ttctggatgc gcctgggtta gaaggtgcac atattaatgg
      901 acaaaaatac aatcgaacaa acagcaaagg ccaggttgtt tacgacctga taatacctca
      961 tcgtgaaaac catctggtac ttgatatagc aaacagtgaa agtgaaacag aattgcaggg
     1021 caatcgtcaa attattgcac cttaccgtgg agcagtttct tatgtgcagt ttacaactga
     1081 ccaacgtaag ccctggtata tacaggcact gcgtcccgat ggttcgccat taacctttgg
     1141 ctatgacgta ctggatctcc aggaaaataa tattggagtc gttggccagg gtagtcgcct
     1201 ttttattcgc gtagatgaaa ttcccactgg aataaaagtt gctctcaatg atgaacagaa
     1261 cttattctgt actattactt ttcaacacgt tatcgatgaa aacaaaacat atatatgcca
     1321 gtaaaaggag tttactatga agtggctttt attaatcacc ttgagtctat attcttttat
     1381 tgtgcaaagt gctccctgtg cattgaccaa tgtcggtgaa caacgtggaa catatatact
     1441 caagccactg agtatgaaag gtaatctaac cgccgaaaaa ttgaaaacac cggaaatatc
     1501 attgagtgta cagacttgca agagacaacc aacgccatta aagttcattt tttaacacag
     1561 aacgctttaa ggtttaaagt cggaagtcgt cattatatta ttaatttccc ctttgaatct
     1621 gacggtaaaa aaatagagct tccagggaag tcatcttata atttagaaga aatgctatct
     1681 gcgataaatt tcaccattcc atattctatc gcatctgtat cagatagttc taacaccgca
     1741 gacatttttc ctggaactcc ttttcctttg ttgttcgaaa ttgaagtgag ttca
//
LOCUS       DAPGUL010000283         1784 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.289, whole genome shotgun sequence.
ACCESSION   DAPGUL010000283 DAPGUL010000000
VERSION     DAPGUL010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1784
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.289"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            173..1714
                     /gene="istA"
                     /locus_tag="RHX21_004863"
     CDS             173..1714
                     /gene="istA"
                     /locus_tag="RHX21_004863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001298859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element ISEc12 family transposase"
                     /protein_id="HDV1989901.1"
                     /translation="MPTVPISMRKLKEILRLKYGVGLSHRQIGRSLAISPSVVSRYAN
                     RAAQLGIKQWPLPTGWDDTKLKHAFLQTQVKMKKHSLPDWATVHRELRNKCVTLQLLW
                     EEYCERNPGGFYSYNHYCRMYREWLKTTSPSMRQVHKAGEKLFVDYCGPTVGVTDPET
                     GEIRTAQVIVAVLGASSYTWAEATWSQQLEDWVMSHVRCFQWLGGVPELVVPDNLKSA
                     TSRACKYDPDVNPTYQQMLEHYNVAVLPARPRKPKDKAKAEVGVQVVERWIMARIRHE
                     IFYSLASLNQRIRELLERLNNKIMQKLGYSRAELFIQLDKPALKPLPEASYSYTLVKK
                     VRVHADYHVEIDKHYYSVPCSLLGQQLEAWISGELVRLFNQGQEVAVHPRKRTYGYST
                     RNEHMPEAHRQHATWTPERLLEWAGHIGSETHSYVLHILNSRPHPEQSYRFCLGLLNL
                     HKKYSKARLNAACARALKTKVWRLSGIKSILEKGLDKQPVQDPKPDLLSTMEHENVRG
                     SEYYH"
BASE COUNT          500 a          426 c          414 g          444 t
ORIGIN      
        1 atcactcaat aacttccatc gagatcgggt aataacattt gaacagatcg ctgaataaca
       61 tcgatggaga tcacttttga ctcattttgt tattcagtga tctccatcaa tgttattgga
      121 acttcacagg tgtgttgatc tgtatctttt gccattccgg taaaggatac ctatgccaac
      181 agttccaatt tctatgagaa aacttaaaga aattcttagg cttaaatacg gtgttggact
      241 cagccatcga caaattggtc gtagtcttgc aatctcccct tccgttgtat ccagatatgc
      301 taatcgggcg gctcaacttg gcataaagca gtggccctta cctacaggat gggatgatac
      361 aaaactaaaa catgcgttcc ttcagaccca ggttaagatg aagaagcact ctctgcctga
      421 ctgggctaca gtacaccggg aactgcgtaa taaatgcgtg acgctgcagc tactctggga
      481 agaatactgt gagcgtaatc caggcggttt ttacagctat aaccattact gccggatgta
      541 ccgtgaatgg ctcaaaacca cttcaccatc aatgcgtcag gtacataaag ctggcgaaaa
      601 acttttcgtt gattactgtg gacctaccgt tggcgttacc gaccctgaga ccggagaaat
      661 aagaactgct caggtcatcg tagctgttct cggggcatca agttacacat gggcagaggc
      721 cacctggtct cagcagcttg aagactgggt gatgagtcat gttcgctgct tccagtggtt
      781 gggtggcgtt cctgaacttg ttgttccgga caatctgaaa agcgccacat ccagggcatg
      841 taagtatgat cctgacgtta accctaccta ccagcagatg cttgagcatt ataatgtcgc
      901 agttttgcct gcgcggccac gtaaaccgaa agataaagcc aaagctgaag ttggcgttca
      961 ggttgttgaa cgctggatca tggcccgaat caggcatgag atcttctaca gccttgcatc
     1021 gcttaatcag cgcattcggg agttgctgga aagactgaat aacaaaataa tgcagaagtt
     1081 gggttattca cgtgcagaac tcttcatcca gcttgataaa cccgcactga agcctcttcc
     1141 tgaagccagt tacagttaca ccctggtgaa gaaagtcaga gttcatgccg attaccacgt
     1201 ggaaatcgac aaacattact actcggttcc atgttcgctg ttaggccagc aactggaagc
     1261 atggatctcc ggagaactgg taagactctt caatcagggg caggaggttg ctgtgcaccc
     1321 gcgcaagcgt acttatggct acagtacccg caacgagcac atgcctgaag ctcatcgaca
     1381 gcatgccacc tggacgccag agcgtcttct ggaatgggcg gggcacatag gcagtgaaac
     1441 tcatagttat gtgcttcata tactgaactc tcgtccacat ccggaacaaa gctatcgctt
     1501 ctgccttgga ctcctgaacc ttcataaaaa atacagtaaa gccagactta atgcagcatg
     1561 tgcaagagct ctgaaaacaa aggtatggcg tctgtcaggt attaaatcga tcctggaaaa
     1621 aggtctggat aaacaacctg ttcaggatcc aaaaccagat ctgttatcca cgatggaaca
     1681 cgaaaacgta cgcggcagtg agtattacca ctgatacggg atccaatgat gaatcatctt
     1741 tacgaacaac tgaccgcact taaactcacc ggcttccgtg atgc
//
LOCUS       DAPGUL010000284         1769 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.290, whole genome shotgun sequence.
ACCESSION   DAPGUL010000284 DAPGUL010000000
VERSION     DAPGUL010000284.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1769)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1769)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1769
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.290"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(506..1330)
                     /locus_tag="RHX21_004864"
     CDS             complement(506..1330)
                     /locus_tag="RHX21_004864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989902.1"
                     /translation="MNRSNEEDIEKAKSLISTGAEIAGAAVGGAIGFFATGPVGVAGA
                     GSLGVIVAKAGAKLLGDVADRTMSAREKVRVGAAAAVAFNKIEKVALSGNEPRKDGFF
                     NSEEGKRSDAEEVLEGTLRRAREEYEEKKILLLGNFYANMVYSPGVSTEEANYYLRLF
                     DSLTYRQLCIMSLIMMKPQYSDFQNLRSHDYRTQNANMQASTVALLQEIYALYNLGLV
                     CVRSAGGNGYVSLLAWHDIIPLGLEFTGLGERFYKLFMGGGSFSLPDITTIAEALR"
BASE COUNT          542 a          370 c          341 g          516 t
ORIGIN      
        1 tatgcaaaga ttgagagtga gtgaagacag gaagtaaata acaatagaga tcatataaaa
       61 aagggagtga gcaaagagta tataaagagt aaatataatt atagtaataa acctaaatta
      121 aaattatcca tgtttgatga gtggaaataa tgtaggaaat gaacctgttt aaaaactcgt
      181 tatcatagat taaccgttca gatactcaac gaactcaata aattggctga gtctggtgta
      241 ttagctcaga cctgatctga cagttaccgg ttatgtaaac atttatcgtt gctgccaatg
      301 cttggattat tggcctcaag gtattcgctt tacttacaag ctaattttga aacagatgtc
      361 gcgctatttt aggaagagaa tctatgcaaa agtctgctat gagcgaggaa cggatgttta
      421 tgattgttat caacgaggcc ccatgtctaa caatctcctg tgttaatgag caggggctgg
      481 aaactttgaa tcaaaatgtt catttttaac gcaaagcttc tgcgatagta gtaatatcgg
      541 gaagtgaaaa gcttcctccc cccataaaaa gtttgtaaaa cctttcacct aaccctgtaa
      601 attctaatcc taaagggatg atatcatgcc atgccagcaa agatacataa ccatttccgc
      661 cagcactcct aacgcagact aatcccaaat tatacagagc ataaatttct tggaggagtg
      721 ctacagtact tgcttgcata ttggcatttt gggttcgata gtcatggctt ctcagatttt
      781 gaaagtcaga atattgtggt ttcatcatga tcaaactcat aatacagagc tgccgatacg
      841 tcagtgaatc gaacaaccgg agatagtaat tcgcttcttc tgtactcact cccggagagt
      901 agaccatatt tgcataaaaa ttccctagaa gaagaatctt cttttcctca tactcttcac
      961 gcgcccttct taacgtcccc tccagaactt cttctgcatc actgcgtttt ccttcttcag
     1021 agttaaagaa accatctttt ctgggttcat tacctgacag agcgaccttt tcaattttat
     1081 tgaatgcaac tgcagcagca gcaccaacgc ggactttttc gcgtgcagac atcgtacgat
     1141 cagccacatc accgagaagt tttgcaccag ctttcgcgac aatcacccct aaagaaccag
     1201 ccccggcaac tcccacaggg ccagttgcaa aaaagccaat tgcaccgcca actgcagcgc
     1261 cagctatctc tgcacctgtc gaaatcagcg atttggcttt ttcaatatct tcttcgtttg
     1321 atctattcat agctttatct tctagggcag aataatggat ggttgtaatg aagatacctt
     1381 taccacatga aaatcattaa ctccacatta cctgatgaca gtgaactgtt gtccgttgat
     1441 taacgcgcaa taatgttatt caaatggatg tttgaccacc tagaactaac cgctgtaatg
     1501 acatctattt ttggtacaga ggggaccaac cggcgtgtcc tctggtccga tatgagcgaa
     1561 gagcggaagt tcgcagttgc tcttataact tataaacata tgacttacct atcgctgtct
     1621 taatcaatag ggcccaagtg agtgcgttac catactaggg ctgacttcat ggtataagaa
     1681 aaaccttttt gcaaaaggta aattttcctt ttgcatcaaa agatatgatt gcttaaaatg
     1741 gtttgcaatt taatagtgcg gttggagtt
//
LOCUS       DAPGUL010000285         1744 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.291, whole genome shotgun sequence.
ACCESSION   DAPGUL010000285 DAPGUL010000000
VERSION     DAPGUL010000285.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1744
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.291"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..694)
                     /gene="emrY"
                     /locus_tag="RHX21_004865"
     CDS             complement(<1..694)
                     /gene="emrY"
                     /locus_tag="RHX21_004865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter permease
                     subunit EmrY"
                     /protein_id="HDV1989903.1"
                     /translation="MAITKSTPAPLTGGTLWCVTIALSLATFMQMLDSTISNVAIPTI
                     SGFLGASTDEGTWVITSFGVANAIAIPVTGRLAQRIGELRLFLLSVTFFSLSSLMCSL
                     STNLDVLIFFRVVQGLMAGPLIPLSQSLLLRNYPPEKRTFALALWSMTVIIAPICGPI
                     LGGYICDNFSWGWIFLINVPMGIIVLTLCLTLLKGRETETSPVKMNLPGLTLLVLGVG
                     GLQIMLDKGRDLD"
     gene            complement(694..>1744)
                     /gene="emrK"
                     /locus_tag="RHX21_004866"
     CDS             complement(694..>1744)
                     /gene="emrK"
                     /locus_tag="RHX21_004866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="multidrug efflux MFS transporter periplasmic
                     adaptor subunit EmrK"
                     /protein_id="HDV1989904.1"
                     /translation="LEDMISTDDAYVTGNADPISAQVSGSVTVVNHKDTNYVRQGDIL
                     VSLDKTDATIALNKAKNNLANIVRQTNKLYLQDKQYSAEVASARIQYQQSLEDYNRRV
                     PLAKQGVISKETLEHTKDTLISSKAALNAAIQAYKANKALVMNTPLNRQPQVVEAADA
                     TKEAWLALKRTDIKSPVTGYIAQRSVQVGETVSPGQSLMAVVPARQMWVNANFKETQL
                     TDVRIGQSVNIISDLYGENVVFHGRVTGINMGTGNAFSLLPAQNATGNWIKIVQRVPV
                     EVSLDPKELMEHPLRIGLSMTATIDTKNEDIAEMPELASTVTSMPAYTSKALVIDTSP
                     IEKEISNIISHNGQL"
BASE COUNT          486 a          394 c          352 g          512 t
ORIGIN      
        1 aatccagatc gcgcccttta tcaagcataa tttgcaagcc accaacaccg agcactaaca
       61 gggtcagtcc tggtagattc attttgaccg gtgaagtttc agtttctctt cctttaagta
      121 aggttaagca taatgtcagg acgataatac ccatagggac attgattaaa aatatccaac
      181 cccagctaaa gttatcgcaa atatatccgc ctaatatcgg cccacatatc ggagcgataa
      241 tcacggtcat tgaccataat gccagagcaa atgttctttt ttctggtgga taattcctta
      301 ataataaact ctgtgacagt ggaattaacg gccctgccat taacccctga acgactctaa
      361 aaaatatcag cacatcaaga ttggtcgata aactacacat taatgaagac agcgaaaaaa
      421 aagtgactga aagtaaaaat aaccttaatt cgcctattct ttgtgccagc ctgccggtaa
      481 cagggatcgc aatggcattt gctacgccaa acgaggtgat aacccaggtg ccttcgtctg
      541 ttgatgctcc cagaaagcca gatattgtcg gtattgcgac gttagaaata gtggaatcca
      601 acatttgcat aaacgtcgct aatgacaatg caatagtgac gcaccataac gtcccaccgg
      661 ttaatggtgc cggagttgat ttagtgattg ccattaaagt tgtccattat gcgaaataat
      721 gttgctaatt tctttttcta tcggactggt atcgataact aaagccttac tggtataagc
      781 cggcatggac gtcacggttg aagccaactc aggcatctca gcaatgtctt cgttcttcgt
      841 atcaatagtt gcagtcatcg ataaaccaat gcgcaagggg tgttccatga gttcttttgg
      901 atcaagagaa acttcaaccg gtacacgctg aacgattttg atccagttcc ctgtcgcatt
      961 ttgtgcaggt aataaggaga acgcattgcc ggttcccata ttgatccctg tcacccggcc
     1021 atgaaacaca acattctcac cataaagatc gctgataata ttgaccgatt gaccaatccg
     1081 tacatccgtg agttgtgttt ctttaaagtt ggcattaacc cacatttgac gtgctggtac
     1141 gacagccatt aacgattgtc cgggactcac tgtttcgccg acctgaacac ttcgctgggc
     1201 aatatagccg gtaaccggac tcttaatatc cgtacgttta agcgccaacc aggcttcttt
     1261 ggttgcatcc gcagcttcaa cgacttgtgg ctgacggttt aatggtgtgt tcattactaa
     1321 agctttattc gctttataag cctggatagc ggcattcaat gccgctttgc tacttattaa
     1381 cgtatctttg gtatgctcca gcgtttcttt tgaaataacc ccctgcttcg ctaaaggcac
     1441 acgacggtta taatcttcta aagattgttg atactgaata cgtgctgaag cgacttcggc
     1501 actgtattgt ttatcctgta agtacagttt attcgtttgc cgaacaatat ttgccagatt
     1561 atttttagct ttattgagtg cgatagtggc atcagtttta tccagtgaaa ctaaaatgtc
     1621 accctgtcga acgtagttcg tatctttatg attaactaca gtgacactac ctgagacttg
     1681 tgcagaaatt ggatctgcat tccccgtgac ataggcgtca tctgtactaa tcatgtcttc
     1741 taat
//
LOCUS       DAPGUL010000286         1725 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.292, whole genome shotgun sequence.
ACCESSION   DAPGUL010000286 DAPGUL010000000
VERSION     DAPGUL010000286.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1725)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1725)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1725
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.292"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..391)
                     /locus_tag="RHX21_004867"
     CDS             complement(<1..391)
                     /locus_tag="RHX21_004867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EscU/YscU/HrcU family type III secretion system
                     export apparatus switch protein"
                     /protein_id="HDV1989905.1"
                     /translation="MANKTEKPTQKKLQDASKKGQILKSRDLTISVIMLVGTLYLGYV
                     FDVHHIMSILEYILDHNAKPDIWDYFKAMGVGWLKTNIPFLLVCMFTTILVSWFQSKM
                     QLATEAVKFKFDSLNPVNGLKRIFGLKT"
     gene            complement(400..1167)
                     /gene="sctT"
                     /locus_tag="RHX21_004868"
     CDS             complement(400..1167)
                     /gene="sctT"
                     /locus_tag="RHX21_004868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system export apparatus
                     subunit SctT"
                     /protein_id="HDV1989906.1"
                     /translation="MGEAILYQLHSLLAATALGFCRLAPTFYLLPFFASGNIPTVVRH
                     PIIIVVSCALVQHYHYELLNLNEIDIALFAAREIIIGLFIACLLASPFWMFLAIGSFI
                     DNQRGATLSSTLDPATGVDTSELARLFNLFSAAVYLTKGGMNFILETLWQSYNLWPSG
                     NFNFPKLEPLFSYINNIMTHTIVYASPVIAVMLGGEAVLGLLACYASQLNAFAISLTV
                     KSALAFLILIIYFAPILAERVMPLSFFPEQLQLYIEK"
     gene            complement(1169..1429)
                     /locus_tag="RHX21_004869"
     CDS             complement(1169..1429)
                     /locus_tag="RHX21_004869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EscS/YscS/HrcS family type III secretion system
                     export apparatus protein"
                     /protein_id="HDV1989907.1"
                     /translation="MDDIVFAGNRALYLILVMSAGPIAVATFVGLLVGLFQTVTQLQE
                     QTLPFGVKLLCVSICFFLMSGWYGEKLYSFGIEMLNLAFARG"
     gene            complement(1439..>1725)
                     /locus_tag="RHX21_004870"
     CDS             complement(1439..>1725)
                     /locus_tag="RHX21_004870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="EscR/YscR/HrcR family type III secretion system
                     export apparatus protein"
                     /protein_id="HDV1989908.1"
                     /translation="EEIIDDDNISIFSLLPAYALSEIKSAFIIGFYIYLPFVVVDLVI
                     SSVLLTLGMMMMSPVTISTPIKLILFVAMDGWTMLSKGLILQYFDLSINP"
BASE COUNT          596 a          354 c          295 g          480 t
ORIGIN      
        1 cggtttttaa gccaaatata cgctttaagc catttactgg attcaatgaa tcaaacttaa
       61 atttaacagc ttcagttgct aattgcattt tactttgaaa ccaggagaca agtattgttg
      121 tgaacatgca aaccagcaaa aaaggaatgt tcgttttcaa ccaaccaacc cccatagctt
      181 taaaatagtc ccaaatatct ggtttagcgt tatgatcaag gatgtattca agaatcgaca
      241 taatgtgatg cacatcaaaa acatatccga gatataaagt acccacaagc attattacag
      301 agatggttaa gtctctactt tttagaattt gccctttttt agaagcatcc tggagtttct
      361 tttgtgttgg cttttcagtt ttattggcca tgaaacactc tatttctcaa tgtatagttg
      421 caattgttct gggaaaaagg ataacggcat tactcgttca gccagtattg gggcaaaata
      481 aataattaat attaaaaatg ccagcgcact tttgacagtc agtgaaatgg caaaagcatt
      541 tagttgtgaa gcataacatg ccagcaatcc caggacagcc tcaccgccca gcataacggc
      601 aatcacgggg cttgcgtaaa cgatagtatg agtcattatg ttattaatat atgagaataa
      661 aggctctaat ttaggaaaat taaaattgcc tgaaggccat aaattataac tttgccaaag
      721 agtttccaga ataaagttca ttccaccttt agtaagataa accgcagcag agaaaaggtt
      781 aaataatctt gctaattccg aggtatcgac acctgtagcc ggatccaaag tactacttaa
      841 tgttgcaccg cgttggttat cgataaagct acctatagca aggaacatcc aaaacgggga
      901 tgctaataag catgcaataa acagccctat gataatttct ctggcagcga acaaagcaat
      961 atcgatttca tttaagttca ataattcata gtggtaatgc tgaactaatg cacatgatac
     1021 cactattatt attgggtgac gaactactgt tggtatattc ccactggcga aaaatggtaa
     1081 caaatagaaa gttggtgcca atcggcaaaa accgagcgct gtagcagcca gcagactatg
     1141 caactgatag agtatcgcct cccccatgct atcctctcgc gaatgctaaa ttcagcattt
     1201 cgataccaaa tgaatataat ttttcaccat accacccgct cattaaaaaa aagcaaatac
     1261 ttacgcacaa taatttcacg ccaaatggca acgtctgttc ttgcaactgc gttaccgttt
     1321 gaaaaagccc taccaataaa ccaacaaatg tcgcaactgc aataggtcct gcagacataa
     1381 ctaaaatcag atacagcgcc ctattccccg caaaaacaat atcgtccata ttttttcctc
     1441 agggattaat ggataggtca aaatattgta aaatgagccc ttttgataac attgtccaac
     1501 cgtccatcgc gacaaacaaa attaatttta tcggtgtaga tatggttacc ggactcatca
     1561 tcatcatacc taacgttaac agaacgctgg atataaccag atccactacg acaaagggta
     1621 aatagatata aaaacctata ataaatgcac tttttatctc actcaatgca tatgcgggca
     1681 gtaacgagaa aattgaaata ttatcatcat cgattatctc ttcat
//
LOCUS       DAPGUL010000287         1721 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.293, whole genome shotgun sequence.
ACCESSION   DAPGUL010000287 DAPGUL010000000
VERSION     DAPGUL010000287.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1721
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.293"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(104..1721)
                     /locus_tag="RHX21_004871"
                     /pseudo
     CDS             complement(104..1721)
                     /locus_tag="RHX21_004871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001530200.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
BASE COUNT          351 a          524 c          394 g          452 t
ORIGIN      
        1 tgttttatgt ccataaaata cgatgtcaga atttgaattg ttatcaaacc caaggtaaac
       61 aacaaataaa caaagggtaa ttaaaaaaat gacaagtttg cctctaataa tttgaagcat
      121 ctgaactccc ttgctttgct tttattggat tatctgcttt tataccatct aacccgaaga
      181 gttgcccagt gttatatttt tcaatacatg catcgctaca tttggcagaa aaatcgccac
      241 aagcaatacc gacagtgtta tttttaagat ccatgattct ttctttagct ggctgacctt
      301 gtctattccc tgccgcctca tgatttttac ctatcacgtc agctattgtt gatccaaatg
      361 tcttagtcat tcgacacatc aagtaacaat gtctcattgc atcggcggcc ccattatgag
      421 ctccgccaac aatagcatcc atatcataac cgaactggta agcactgtta gtaatgctgt
      481 ttgcagcaat caatccaggt acaccagata cggcataaat tagtccacct gatgtcatat
      541 tctcaatcgc atctaacccc attgggtcta tcacttgtat gggattcaac ggatactgat
      601 acatattcca tccacctctc aacccaatcg ggtccggggt gatataccgc ccctgcaacg
      661 gatcgtagta ccggtgacgg ttatagtaca gccccgactc cttatcatac tgctgccccg
      721 gcagccggta cggctggtgc aggtgatgcg ggttctcctc attaagctgg ttgccccatt
      781 catcatattc cgcgctccac gccgtattgc cgtcttcact gataagcgcc agcggcaggc
      841 cccggtggtc acagtgataa agatgtattt ttcgctcagg caaataaacc ggctctatct
      901 gtgccgccag ccgctccacc gtcagcccgc actgcgcaag ccactggcgg ctttcactgc
      961 tcacgcagtt tgcccggatt tccccctcca gcctgtccag cagccccacc agttcagccg
     1021 gaaataccac gccgtgcccg tcctcgctcc cttcctgctg tatcttctcc gccaggctgc
     1081 ggcactgcgc tttctcccgt tcaccgttgt ctgtttcgat gcggatgagc ggcgcgaagc
     1141 tccccggctg gtataccgtc tggatacgcg tggtgtcggt ctgtaccgtc gtcagcctgt
     1201 cgccgtccca gccgtaccat gtctcctccg gtttacgcga cagcgacatc caccccgtca
     1261 ggtcacgctc ccgccgccat acccgtttcg ccattcgccg tcccagcggg tcgtagaggt
     1321 agcggctctc gaccagtggc tcgccatgct gtatccgcgt gtggaacacc aggcggtgct
     1381 ggctgtcgta gtggtagtgg tgggtccgct cgtcgtccgt ccgtatcaca cccgtcggga
     1441 tgcggtccgt cttctccgtc agtctgccgt tcgcccgtca gacggccttt atcgtcatag
     1501 ccgtagtgga ccgccacacg gtggccttca ctcaggtggc tgatttctgt cagccagccg
     1561 tggtcgtcat actgccactg ctccgccggt tcaccgttca ccgtgcgccg ggtgatacgg
     1621 tccgacgcat cgtaatgcca gagggtgata agcccctcat cttcactctg cgtgagtttt
     1681 ccggtcaggt catactggta acgttgcgtc cggccgtcaa a
//
LOCUS       DAPGUL010000288         1707 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.294, whole genome shotgun sequence.
ACCESSION   DAPGUL010000288 DAPGUL010000000
VERSION     DAPGUL010000288.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1707
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.294"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..336
                     /locus_tag="RHX21_004872"
     CDS             <1..336
                     /locus_tag="RHX21_004872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDV1989909.1"
                     /translation="QYCAYDYRVIQEQFGLKTSMSRKGNCYDNAPMESFWGTLKNESL
                     SHYRFNNRDEAISVIREYIEIFYNRQRRHSRLGNISPAAFRENIIRWLLKKRTNGSVR
                     YCQYTSADH"
     gene            452..796
                     /locus_tag="RHX21_004873"
     CDS             452..796
                     /locus_tag="RHX21_004873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ProQ/FinO family protein"
                     /protein_id="HDV1989910.1"
                     /translation="MTKRQRKNRKRINRLVEHWPELFNREKTQPLKVEIPDDLIQDIA
                     IRELAFGAGALRAAVASYVQSPRYYRALMAGGARYDQKGQPCGEVTPQEQKEAETRLM
                     VLNDRQKARKPR"
     gene            complement(815..1363)
                     /locus_tag="RHX21_004874"
     CDS             complement(815..1363)
                     /locus_tag="RHX21_004874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001167424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989911.1"
                     /translation="MQITEALISEPGDIRRFVQQAVDHWPHLLAFYFTLHSAEGNING
                     QQIHAFCTSFYRQVHERITERNHMASPASPLVLRWLREQHGGATIRCLLLLSQTSICH
                     PRASVTVDEQCSQVVDLLQHSWQVISAGGQCRVERCFRVARGDTSGQYVALKTAALSL
                     GLPVVTAITHRPVQRCTLITAQ"
BASE COUNT          527 a          418 c          387 g          375 t
ORIGIN      
        1 cagtactgcg catacgatta ccgggtcata caggagcagt ttggtctgaa aacatcaatg
       61 tcgcgtaaag gtaactgtta cgacaacgct ccgatggaaa gcttctgggg aacgctgaaa
      121 aatgagagcc tgagccacta tcgttttaat aaccgggatg aagccatctc agtaatacgg
      181 gaatacattg agattttcta caatcgtcag cgtcgtcact ctcgtctggg gaatatctcc
      241 ccggcagcct tcagggaaaa tatcatcaga tggctgctta agaaaagaac aaatggtagt
      301 gtccgctatt gccagtacac ctcagctgac cattaaccgt aaaccgcagg gtattttcag
      361 taagtcaccg gcaacgccgc tgcaggataa aacgaacaca gtacacaacg agaagcctct
      421 tcgggtgagg aatcaaacac catggcgaca tatgacaaaa cgccagcgca aaaaccgtaa
      481 gcgtattaat cgtcttgtgg aacactggcc tgagttattc aaccgggaaa aaacccaacc
      541 gcttaaagtt gagatacctg acgacctgat acaggatatc gccatcagag aactggcatt
      601 tggcgcaggt gcattacgcg cggcagtagc gtcttatgtg cagtctccgc gctattaccg
      661 tgcgttaatg gctggcggcg cccgttacga ccagaagggg cagccgtgcg gggaagtgac
      721 tccacaggaa cagaaagagg cagagacccg gctaatggtg ctgaatgacc gacaaaaagc
      781 cagaaaacct cgttgactac acaactgcgc tgattcactg agctgtaatc aatgtacagc
      841 gctgtaccgg acgatgggta atggcggtca caaccggtaa ccccagagac aatgcggcag
      901 tttttaacgc tacatactga ccggatgtat caccccgggc aacccgaaaa cacctttcca
      961 cccggcattg tccgccagca cttatcacct gccagctatg ttgcagtaaa tccaccactt
     1021 gcgaacattg ttcatcaact gtgacactgg ctcgcgggtg acaaatactc gtctggctga
     1081 gcagcaacag gcatcgaatt gttgctcctc catgttgttc ccgcaaccag cgtaatacca
     1141 gcggcgatgc cggactggcc atgtgattac gctcagtaat acgttcgtgc acctgtcggt
     1201 aaaaggaagt acagaatgca tgaatctgtt gcccgttgat atttccttct gccgaatgga
     1261 gtgtgaagta aaatgccagc aaatgcggcc agtggtccac cgcctgctga acaaaacgcc
     1321 ggatgtctcc cggctctgaa attaaggctt cggttatttg cacgaaatgt tccttttcaa
     1381 accctgttgg attttgtcaa gccggtacag acacagtaaa gcgcgcatca acacctgaaa
     1441 ggtacgatac aaacacaagt tacaaacaat aagaacggaa ggacaattaa tcagtgagga
     1501 ataataacta aattaaccaa aagaatgtta ctgacaatac caccaatact taaatagcaa
     1561 tatattaatt aatgtaagaa cagatgcccg gtaagacata tacacaatac atccacaaac
     1621 acactctttt cattaaataa accacctgat taaaccatga aagtgtgatg taagtcaaaa
     1681 ttactgacac aatcaattga taatgat
//
LOCUS       DAPGUL010000289         1691 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.295, whole genome shotgun sequence.
ACCESSION   DAPGUL010000289 DAPGUL010000000
VERSION     DAPGUL010000289.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1691)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1691)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1691
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.295"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..843
                     /locus_tag="RHX21_004875"
     CDS             <1..843
                     /locus_tag="RHX21_004875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HDV1989912.1"
                     /translation="DFLNGDPDQPIIMGRTYHQENRTPGSLPGTKTQMTIRSKTYKGS
                     GFNELKFDDATGKEQVYIHAQKNMNTEVLNNRTTDVINNHAEKIGNNQAITVTNNQIQ
                     NIGVNQIQTVGVNQVETVGSNQIIKVGSNQVEKVGIIRALTVGVAYQTTVGGIMNTSV
                     ALLQSSQVGLHKSLMVGMGYSVNVGNNVTFSVGKTMKENTGQTAVYSAGEHLELCCGK
                     ARLVLTKDGSIFLNGTHIHLEGESDVNGDSPVINWNCGATQPVPDAPVPKDLPPGMPD
                     MRQF"
     gene            919..>1691
                     /locus_tag="RHX21_004876"
     CDS             919..>1691
                     /locus_tag="RHX21_004876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308264.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion protein Rhs"
                     /protein_id="HDV1989913.1"
                     /translation="MGGKPAARQGDMTRKGLDIVQGSAGVLIGAPTGVACSVCPGGIT
                     YANPVNPLLGAKVLPGETDLALPGPLPFILSRAYSSYRTRTPAPVGVFGPGWKAPFDI
                     RLQIRDEGLILNDNGGRSIHFEPLFPGEISYSRSESLWLARGGVAEQHSSQPLSALWQ
                     VLPEDVRLSPHVYLATNSLQGPWWILSWPERVPGADEVLPPEPPAYRVLTGVVDGFGR
                     TLTFHRAAEGDVAGAVTGVTDGAGRCFHLVLTTQAQRAEA"
BASE COUNT          398 a          424 c          557 g          312 t
ORIGIN      
        1 gacttcctca acggcgatcc ggaccagccg attattatgg ggcgtaccta ccaccaggaa
       61 aaccgcacac ccggcagcct gccggggacg aagacgcaga tgaccattcg ttcgaaaacc
      121 tataagggca gcgggtttaa tgaactgaag tttgacgatg cgacagggaa agaacaggtc
      181 tacatccacg cgcagaagaa catgaacacc gaggtgctga ataaccgcac cactgatgtg
      241 ataaacaacc atgccgaaaa aataggtaac aaccaggcga tcaccgttac caataaccag
      301 atccagaaca ttggcgttaa tcagatacag acggttggtg tcaaccaggt ggaaacggtg
      361 ggcagtaacc agattatcaa agtgggatca aaccaggttg aaaaggtggg gatcattcgt
      421 gcgctgacgg tgggtgtggc ttaccagacg acggtaggcg gcattatgaa tacctcggtg
      481 gcgttgttgc agtcctcaca ggtagggctg cataaatcac tgatggtggg aatgggctac
      541 agcgtcaatg tggggaataa cgtcaccttc tcggtgggca agacaatgaa ggaaaacacc
      601 ggacaaacag cagtttattc tgccggtgag catcttgaac tctgctgtgg taaggcaagg
      661 ctggtgctga cgaaggacgg aagcatattt ctcaatggta cgcacattca tctggaaggg
      721 gagtcggatg tgaacggtga ttcgccagtg attaactgga actgtggtgc cacacaacct
      781 gtaccggatg cgcctgtgcc gaaagattta ccccccggaa tgccggatat gcggcaattt
      841 tgagtcaggt gcaaaaaatt aaaacggaac tggtgcagtg accagataaa ccatattaaa
      901 agcagaagga attgattcat gggcggaaaa ccggcggcgc ggcagggtga tatgacccgc
      961 aagggactgg atattgtgca gggttcagcg ggggtgctga taggtgcgcc gacgggagtg
     1021 gcctgttcgg tatgtccggg agggattacc tatgctaacc cggtgaaccc gctgctgggt
     1081 gcgaaggtgc tgccgggcga gacggacctt gcgctgcccg gcccgctgcc gtttattctt
     1141 tcccgcgcct acagcagcta ccggaccaga acacccgcgc cggtgggggt gtttggtccc
     1201 ggctggaaag cgcccttcga tatccgctta cagatacgcg atgaaggcct gatactcaac
     1261 gacaacggcg gcaggagcat tcactttgag ccgctgtttc ccggcgagat aagctacagc
     1321 cgcagcgagt cactctggct ggcgcggggc ggggtggcgg agcagcacag ttcgcagccg
     1381 ctaagcgcac tctggcaggt gctgccggaa gatgttcgcc tgagtccgca tgtgtacctg
     1441 gcgacaaaca gccttcaggg gccgtggtgg atactcagct ggccggagcg ggtgccgggg
     1501 gcggacgagg tgctgccgcc ggagccgccc gcataccggg tgctgacggg cgtggtggac
     1561 ggcttcgggc ggacgctgac tttccaccgg gcggcggagg gtgacgtggc gggcgcggtg
     1621 acgggggtga cggacggcgc gggccgctgt tttcacctgg tgctgaccac acaggcgcag
     1681 cgggcggaag c
//
LOCUS       DAPGUL010000290         1593 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.296, whole genome shotgun sequence.
ACCESSION   DAPGUL010000290 DAPGUL010000000
VERSION     DAPGUL010000290.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1593)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1593)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1593
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.296"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(1..749)
                     /locus_tag="RHX21_004877"
                     /pseudo
     CDS             complement(1..749)
                     /locus_tag="RHX21_004877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415229.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
     gene            complement(780..1106)
                     /locus_tag="RHX21_004878"
     CDS             complement(780..1106)
                     /locus_tag="RHX21_004878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989914.1"
                     /translation="MKYIIFLFRAIWLALSLLILFFSMHRLSLLDSTRDVSELISLMS
                     YGMMVICFPTGIVFFIALIFIGTVSDIIGVRIDSKYIMAIIIWLYFLSGGYIQWFVLS
                     KRIINK"
     gene            complement(1106..1525)
                     /locus_tag="RHX21_004879"
     CDS             complement(1106..1525)
                     /locus_tag="RHX21_004879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001466636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989915.1"
                     /translation="MGGTGERSGPDIWGNPFYHQYLCVPDGKGDYTCGGQDQRGESKG
                     DGLWGPGKASNDTKEAAGRCDLVETDNSCVENCLKGKFKEVRPRYSVLPDIFTPINLG
                     LFKNCQDWSNDSLETCKMKCSGNNIGRFIRFVFTGVM"
BASE COUNT          389 a          422 c          351 g          431 t
ORIGIN      
        1 atttttcgcg ccggcgtgta caccgggtcc atctggtttt gcatctgctc cacggtcagg
       61 ccgcacgatg ccagccagcg gcggctttcc tcactcaccc ggtcagccag gatttcactt
      121 tccagccggt cgagcatctg caccagcacc ggcgggaaca ccacactgcc accgtcttcg
      181 ccgccggact gctgaagggt atccgccagg ctgcggcgct gcgttttcgc ctgctcaccg
      241 gtggcggttt caaccctgat gagtggcgtg aagctccccg gctgataaat cgtctggatg
      301 cgggttctgt cgttctgtat tgtggtcagg cggtcgccgt cccagccgta ccaggtcact
      361 tgcggtttcc gtgacagcga catccagccc gtcaggtccc gttcacgtcg ccacacccgt
      421 tttgccaccc tgcggcccag cgggtcgtaa agatagcggc tttcgaccag cggctctgca
      481 tattgtgtcc gcgtgtagtg caccagccgg tgctgactgt cgtaatggta ccggtgggtg
      541 cgctcatcat ccgtgcggat aaccccttcc gggatgaggt cggttttctc cgtcagcctg
      601 ccgtgacggt cataccggta aagatagtgc gcgtcacggg cgatacggtt atccggccac
      661 atgctgaggg cgctgtccgg gtgcagctcc gggtcgggca ggcggttacc tgccgggtct
      721 gtggcatacg ggatatcaat gcccaggtta catataataa taagagcaat taacttaatt
      781 tatttgttta taatgcgctt acttaataca aaccattgaa tataccctcc tgacagaaaa
      841 taaagccata ttattatcgc cataatatac ttactatcaa tccttacgcc aataatgtct
      901 gatacagtcc ctataaatat tagagcaata aagaatacta tgcctgttgg aaaacatatt
      961 accatcattc cataagacat gagactaatt aactcgctca catcacgagt ggagtctaat
     1021 agtgaaagtc tatgcatgga aaagaatagt attaaaagcg ataaagccag ccatatagct
     1081 ctgaataaaa aaataatata tttcattaca tcactccggt gaatacaaat ctaataaaac
     1141 gtccaatgtt atttccggag cacttcatct tacatgtttc taaagaatca ttagaccagt
     1201 cttggcagtt tttaaatagc cctaaattta taggtgtgaa tatatcaggc aatacagaat
     1261 aacgcggcct tacctcttta aacttccctt ttaaacagtt ctccacacaa ctattatcgg
     1321 tttcaacgag gtcacaacgg ccagcagctt cttttgtatc attacttgct ttacctggcc
     1381 cccatagacc atctcctttt gattctcccc gttggtcttg gccaccacaa gtatagtccc
     1441 ctttaccatc tgggacacaa agatattgat gatagaacgg attcccccat atatctggac
     1501 cgcttctttc accagttccg cccattgaat gcagtggctt aatgcatttt agtgtttcta
     1561 atcctaatgg atctatattt gagatcggat tca
//
LOCUS       DAPGUL010000291         1543 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.297, whole genome shotgun sequence.
ACCESSION   DAPGUL010000291 DAPGUL010000000
VERSION     DAPGUL010000291.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1543
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.297"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..802
                     /locus_tag="RHX21_004880"
     CDS             <1..802
                     /locus_tag="RHX21_004880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF4329 domain-containing protein"
                     /protein_id="HDV1989916.1"
                     /translation="YHCDHRGLPLALISTEGATAWCAEYDEWGNLLNEENPHQLQQLI
                     RLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLYGYQLNPISDIDPLGL
                     SMWEDAKSGACTNGLCGTLSAMIGPDKFDSIDSTAYDALNKINSQSICEDKEFAGLIC
                     KDNSGRYFSTAPNRGERKGSYPFNSPCPNGTEKVSAYHTHGADSHGEYWDEIFSGKDE
                     KIVKSKDNNIKSFYLGTPSGNFKAIDNHGKEITNRKGLPNVCRVHGNM"
     gene            774..1157
                     /locus_tag="RHX21_004881"
     CDS             774..1157
                     /locus_tag="RHX21_004881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417940.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbC/YhhH family protein"
                     /protein_id="HDV1989917.1"
                     /translation="MSAEFMVICKKILFRNCVIVSLFVFTYNTWAQCNNNIKIMRKYE
                     SEGKYTVRNLVKNKAIALELAEIYVKNRYGQDAAEEEKPYEITELTTSWVVEGTIHSD
                     QIAGGVFIIEIGKNDGRILNFGHGK"
     gene            1262..>1543
                     /locus_tag="RHX21_004882"
     CDS             1262..>1543
                     /locus_tag="RHX21_004882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lyase"
                     /protein_id="HDV1989918.1"
                     /translation="MSNTYQKRKASKEYGLYNQCKKLNDDELFRLLDDHNSLKRISSA
                     RVLQLRGGQDAVRLAIEFCSDKNYIRRDIGAFILGQIKICKKCEDNVFNI"
BASE COUNT          531 a          250 c          359 g          403 t
ORIGIN      
        1 gtaccactgc gaccatcgcg gcctgccgct ggcgctcatc agcacggaag gggcaacagc
       61 gtggtgcgca gaatatgatg aatggggcaa cctgctgaat gaagagaacc cgcatcagct
      121 gcagcagctt atccggctgc cggggcagca gtatgatgag gagtccggcc tgtattacaa
      181 ccgccaccgc tattatgacc cgctgcaggg gcgatatatc actcaggatc cgattggact
      241 gaagggggga tggaacctgt atggatatca attgaatccg atatcagaca tcgaccccct
      301 gggtttatct atgtgggagg atgcaaaatc gggggcatgt actaatggtc tttgcggcac
      361 actatccgct atgataggtc cagataaatt tgattctata gatagcaccg catatgacgc
      421 cttaaataaa ataaatagcc aatctatttg cgaagataaa gagttcgctg gtttaatatg
      481 taaggataat agtggcagat atttctcaac agcacctaac cgaggagaaa gaaaaggatc
      541 atatccattc aatagccctt gccctaatgg tactgagaaa gtatcagctt atcatactca
      601 tggtgcagat agtcatggag aatattggga cgaaatattt tcaggtaaag atgagaaaat
      661 agttaaaagt aaagataaca atatcaagtc attttattta ggtacgccca gtggtaattt
      721 taaagcaata gataaccacg ggaaggaaat aacaaacaga aaaggattac ctaatgtctg
      781 cagagttcat ggtaatatgt aaaaaaatat tgtttaggaa ctgtgtcatt gtatctttgt
      841 ttgtttttac atacaacaca tgggcgcagt gtaataataa tattaaaata atgcgcaagt
      901 atgaaagtga aggtaaatat accgttagaa atttggttaa aaataaagct atagcattgg
      961 aattagctga gatatatgtt aagaatcgtt atggacagga tgccgcagaa gaagaaaaac
     1021 catacgaaat cactgagtta acaacaagtt gggttgttga aggtaccatt cactcagacc
     1081 aaattgctgg tggggttttt attatagaaa taggcaaaaa tgatgggaga attctgaatt
     1141 ttggccacgg aaaataagta tgtaaggata atcaaacatc gtgtgcgctg atggcagagt
     1201 aggtggagga ctccagacag tcaaacgata gaaaaagata gcctttatgg aggttcctgc
     1261 aatgtcaaat acataccaga aaagaaaggc aagtaaagag tatggtttat ataatcaatg
     1321 taagaaacta aatgatgatg aattatttcg cttacttgat gatcacaatt ccttgaaaag
     1381 gatttcatct gccagagtat tacagttaag aggtgggcaa gacgctgtta gattggcaat
     1441 tgagttctgc tctgataaaa attatatccg tagagatatc ggagcattta tactcgggca
     1501 aataaaaatt tgcaaaaaat gcgaagataa tgtttttaat att
//
LOCUS       DAPGUL010000292         1539 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.298, whole genome shotgun sequence.
ACCESSION   DAPGUL010000292 DAPGUL010000000
VERSION     DAPGUL010000292.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1539
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.298"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..963)
                     /locus_tag="RHX21_004883"
     CDS             complement(<1..963)
                     /locus_tag="RHX21_004883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDV1989919.1"
                     /translation="MDLLAESITEVAVSGEIANTDRVLNIAYGIDRNFLFGAAVSMQS
                     VVMHNPDLAVKFHLFTDYIDEDYLQRVNAFTSKNANVEVIIYKVSNAFIDIFPSLKQW
                     SYATFFRLVAFQYLSETIENLLYIDADVICKGSLAGLLDINFDEDKFAAVIKDVPFMQ
                     EKPAKRLAIEGLPGNYFNAGVVYLQLEAWAKNDFMNKAIAMLASDPQHTKYKCLDQDI
                     LNILFFGHCIFISGDYDCFYGIDYELKNKSDEDYKKTITDDTKLIHYVGVTKPWNDWT
                     NYPCQKYFNEAYQASCWNDVAFIPATNEKQYQVKYQHAKKNGDTF"
     gene            complement(989..>1539)
                     /gene="rfaY"
                     /locus_tag="RHX21_004884"
     CDS             complement(989..>1539)
                     /gene="rfaY"
                     /locus_tag="RHX21_004884"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lipopolysaccharide core heptose(II) kinase RfaY"
                     /protein_id="HDV1989920.1"
                     /translation="LIDTKYGRYVFKVFAPKTKRNERFLKSFVKGDYYQNLIVETDRV
                     RSAGLTFPNDFYFLAERKIFNYASVFIMLIEYVEGVELNDMPIIPENVKTEIKASMEK
                     LHALNMLSGDPHRGNFIVSKDGVRIIDLSGKSCTAERKARDRLAMERHLGIANEIKDY
                     GYYSVIYRTKLRKFIKKLKGKA"
BASE COUNT          479 a          322 c          263 g          475 t
ORIGIN      
        1 aaacgtatca ccatttttct ttgcatgttg atatttcact tgatactgct tttcattcgt
       61 ggctggaata aacgccacat cattccagca agaagcctga taagcctcat taaaatactt
      121 ctggcaggga taattcgtcc agtcgttcca gggcttcgtt acgccaacat aatgaatcag
      181 cttagtatca tcggtaatgg tctttttata atcttcatcg cttttatttt ttaactcata
      241 gtcaatgcca taaaagcaat cataatcgcc gctaataaaa atacaatgac caaagaacag
      301 aatatttaaa atatcctgat caaggcattt atacttcgtg tgctgcgggt cacttgccag
      361 catagcaatg gctttattca taaaatcatt tttcgcccat gcttcaagct gcagatatac
      421 tacaccggcg ttgaaataat tccctggaag tccctctata gccagacgct tcgctggttt
      481 ttcctgcata aaaggcacat ctttaataac agctgcgaac ttatcctcat caaaattaat
      541 atcaagcaat ccagctaatg agcctttaca gatgacatca gcatcgatat ataacagatt
      601 ttcaatagtt tcactcaaat actggaacgc aactaaacgg aagaatgttg cataagacca
      661 ctgtttcagg ctggggaaga tatcaataaa ggcattggag actttataaa ttattacttc
      721 aacgttagca tttttgctgg taaaagcatt aacacgttgt agataatctt catcaatgta
      781 gtcggtaaag agatgaaact taaccgcaag gtccgggtta tgcataacaa ctgattgcat
      841 agatactgcc gcaccaaata aaaagttacg gtcaataccg taagcgatat ttaacacacg
      901 atcggtgtta gcaatttccc cagagacagc gacttcagta atactctcag ctaataaatc
      961 catgttggtt ccgttttgac tgtgtggttt acgctttgcc ttttaatttt ttaataaatt
     1021 tgcgtagttt ggttctgtag attactgaat agtagccata atcttttatt tcgttggcaa
     1081 tacccaggtg acgttccatg gccagacgat cacgagcttt acgctctgcc gtacagcttt
     1141 taccggatag gtcaattatc ctgacaccat ctttactaac gataaaatta ccccggtgtg
     1201 ggtcgcccga tagcatattt aaggcatgca atttttccat tgaagcctta atttctgttt
     1261 taacattttc tggaataatc ggcatatcat tgagctctac gccctcgaca tactcgataa
     1321 gcataataaa aacactggca tagttgaaaa ttttacgctc agccagaaaa taaaaatcat
     1381 taggaaaagt aagacctgca cttctgacac gatcggtttc aacgatcaaa ttctgatagt
     1441 agtcaccttt tacaaaagat tttaaaaaac gttcattcct tttcgttttc ggggcaaaga
     1501 ctttaaaaac atagcgacca tatttcgtat caatcaatg
//
LOCUS       DAPGUL010000293         1524 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.299, whole genome shotgun sequence.
ACCESSION   DAPGUL010000293 DAPGUL010000000
VERSION     DAPGUL010000293.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1524)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1524)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1524
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.299"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            226..>1524
                     /locus_tag="RHX21_004885"
     CDS             226..>1524
                     /locus_tag="RHX21_004885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001347383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HDV1989921.1"
                     /translation="MTGDLTIKKGTPSVFLRADSGVTALRFYTGDNTERGIIYAGPNT
                     DSLGEVRIRAKTAGGTSGGDLVVRHDGRVEVRDLTVAYKIKSRTIEIANTDTDSSATT
                     LSIYGVQHTPLVLTRSGSSENVSIGFKLDNMNPKYLGIDTNGDLAFGESPDQKQNSKL
                     ITQAKLDKGLTIGGQLAFKGTTAFSAVATFSAGIAGAIEPENIDGQTVNLNNLTIIKS
                     DAGAVKYYICPSSAGGANITNKPDGVTGNFLLRVESTRKVRDSDYANMQTLINSDTKR
                     IYVRFVVNGNWTAWSQVVVSGWNQDVTVRSLTSTTPSKLGGGRIDVLGSTSDYGSMNC
                     TVRGVDSTGTNSAWSVGTSESTGKMLFLKNHRSSAQVLLNGDDGAVQLLSGTVNGATA
                     QALTINKDEVNSTADLVIRKQTGTGNRFALLNSGNSELPVS"
BASE COUNT          438 a          324 c          395 g          367 t
ORIGIN      
        1 ttccagcgtg catttatcaa cggcgcaaag gttgcggtac tggcgcagac ggcacgcacg
       61 gaattataca ttccagacgg atttgttaag caaaccgccg cgccttctgg atatgttgaa
      121 agccccgttg taaggattta cgaccagtta aacaagccgt cgaaatcgga tgttggactt
      181 ggcaacgtaa cgaacgatgc gcaggtaaaa aaaaccggcg atacaatgac cggtgacttg
      241 acaatcaaaa aaggtacacc gtcagtcttc ctgcgggcag acagtggagt caccgctttg
      301 cggttttata ctggcgataa cacagagcgc ggcataatct atgctggtcc taacactgat
      361 tcgcttggcg aagttcgcat cagggcaaag acagcagggg ggacatcagg aggggatctt
      421 gttgttcgtc acgacgggag ggttgaagtc cgtgatctca cagtagcgta taaaattaaa
      481 agcagaacga ttgagattgc aaataccgac actgactcat cggcaactac gctcagcatc
      541 tatggagtac agcacacgcc gttggtttta acgcgttctg gttcttctga aaatgtgtcc
      601 attgggttta agttagacaa catgaaccca aagtatcttg gaattgatac taatggggat
      661 ctggcttttg gtgagagtcc tgatcagaaa caaaacagca aattgatcac gcaagcgaaa
      721 ctcgacaagg gattaacgat tggtggtcaa ctggctttca aaggtacgac agcgttttca
      781 gccgttgcta cgttcagtgc cgggatagca ggagccatcg agccggaaaa cattgacggc
      841 cagacggtta atcttaacaa cctgaccatc atcaagtcag atgccggggc agttaaatac
      901 tatatttgtc catcctctgc aggtggtgca aatatcacca acaagcctga cggcgtaaca
      961 ggtaactttt tgctccgtgt tgaatcgact cgtaaggtta gggattcaga ttatgcgaac
     1021 atgcaaacgc tgattaacag cgacacaaaa cgtatatacg ttcgctttgt tgttaatgga
     1081 aactggacag cgtggagtca ggttgttgtt tccggatgga atcaggatgt aaccgtcagg
     1141 tcgttaacct cgacgactcc atcaaaatta ggtggcgggc ggattgatgt gcttggaagt
     1201 acgtcagatt atggcagcat gaattgtacc gttcgtggtg ttgatagcac tggaaccaat
     1261 tcggcgtggt cggtaggcac atcagaaagc acaggcaaaa tgttgttcct gaaaaaccac
     1321 agaagcagcg ctcaagtgct gttaaatggc gatgatggag cggttcaact actaagtggc
     1381 actgttaacg gtgctacagc gcaggcgcta accatcaaca aagatgaggt taactcaact
     1441 gccgatttag taattagaaa acaaacaggg actggcaatc gttttgcttt acttaattca
     1501 ggtaattcag aactaccagt tagt
//
LOCUS       DAPGUL010000294         1506 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.300, whole genome shotgun sequence.
ACCESSION   DAPGUL010000294 DAPGUL010000000
VERSION     DAPGUL010000294.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1506)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1506)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1506
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.300"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(14..748)
                     /locus_tag="RHX21_004886"
                     /pseudo
     CDS             complement(14..748)
                     /locus_tag="RHX21_004886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311743.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EscJ/YscJ/HrcJ family type III secretion inner
                     membrane ring protein"
     gene            complement(789..1076)
                     /gene="sctI"
                     /locus_tag="RHX21_004887"
     CDS             complement(789..1076)
                     /gene="sctI"
                     /locus_tag="RHX21_004887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system inner rod subunit
                     SctI"
                     /protein_id="HDV1989922.1"
                     /translation="MSVSNMPPIDRAEQSTAHEIQQAKVIDLNDRVLNLDNPDDKMIS
                     AFANYAVQTENWQQNALQALRSDKEGLTPEKLLVLQDHVLNYNVEVSLVEH"
     gene            complement(1096..1336)
                     /locus_tag="RHX21_004888"
                     /pseudo
     CDS             complement(1096..1336)
                     /locus_tag="RHX21_004888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311745.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system needle complex
                     protein"
     gene            complement(1350..>1506)
                     /locus_tag="RHX21_004889"
     CDS             complement(1350..>1506)
                     /locus_tag="RHX21_004889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001365813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PrgH/EprH family type III secretion apparatus
                     protein"
                     /protein_id="HDV1989923.1"
                     /translation="NNYVDEYYKQWGKQYVRFNVNLKNQDTNNSSFSYGDNRFEKSQG
                     SNWTFQE"
BASE COUNT          445 a          307 c          248 g          506 t
ORIGIN      
        1 cgctctcata tgtctactta attttcaacc tgactaaatt agttagaatg gccctatact
       61 tccataacag ccagcaagtc gctacggata ttaatgcaag taagatagaa accggcatag
      121 ccttatcata agcaaaaaca ggttcgctaa tttcatatgt tggtgcttgc tcaataatgt
      181 ctcttcgttt tgacaataca acagaaatat tttcatattg tacgcttgca gagctattaa
      241 caataaatct cttgatatca tttattttta tttctgggtt gatatctttt tcatatactg
      301 caagtacaga aatatgaatt ggtaaagcag ttttaccact atcgccatta tcaacatcgt
      361 aactaacatg tactctcgaa gaaataatgc catccataat tttgagagat tgctctaacc
      421 gctgctcaat agcagaatat agccttgctt tttccgctcg tggagatgaa acgagtgcat
      481 ctgcagggaa catctgcgat atttgaatat caggcttacc cggtagattg tagattttta
      541 gccaatccac cgcagaagca aaatccgttg gttcgacaaa tattgaaaat cctgttttgc
      601 cttaatcctt cttttcagca ttaatattat gtctttgtaa aacagcaagg acatcattag
      661 cttgctgttg atcaagatgg ttcaataatt cctgctgctt gcagccgcac aacagcagga
      721 taaacaataa taatgatata tatttcatga gcgggtcaac gtctcaactg cagcgacaat
      781 ctttcttgct aatgttccac caatgaaacc tcgacattat aattaagcac atgatcctgc
      841 aagactaata atttttcagg agttaacccc tctttatcag accttaatgc ttgtaacgca
      901 ttttgctgcc aattttcagt ttgtacagca tagttggcaa aagcggagat cattttatca
      961 tccgggttgt caagattgag aacccggtca tttaaatcaa tcactttcgc ttgctgtatt
     1021 tcatgagcag ttgattgctc agctctatca ataggtggca tattgcttac tgacataata
     1081 aaatccttat ccagtttagc ggaagttttg tatgattgct gaatcaagat ctttatacgc
     1141 ttttacaacg ttagattgcg catttcgata taatgtatac tcagctaatg cactttgata
     1201 ttcggcaaga aatttcgtgt cggagggatt ggttggctaa atcctccaac gctttttcaa
     1261 cttgctggtt cagatcatca acgccctgat caaattgatt gctgatatcc ataatataac
     1321 cattccaatc tgccataagt cctcctcaat tattcctgaa atgtccagtt gctaccttga
     1381 gacttctcga atcggttatc tccgtagcta aatgaactat tatttgtgtc ctgatttttc
     1441 aaattcacat taaatcttac atattgttta ccccattgtt tataatattc gtcaacatag
     1501 ttatta
//
LOCUS       DAPGUL010000295         1497 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.301, whole genome shotgun sequence.
ACCESSION   DAPGUL010000295 DAPGUL010000000
VERSION     DAPGUL010000295.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1497)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1497)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1497
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.301"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            170..574
                     /gene="stpA"
                     /locus_tag="RHX21_004890"
     CDS             170..574
                     /gene="stpA"
                     /locus_tag="RHX21_004890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein StpA"
                     /protein_id="HDV1989924.1"
                     /translation="MSVMLQSLNNIRTLRAMAREFSIDVLEEMLEKFRGVTKERREEE
                     EQQQRELAERQEKISTWLELMKADGINPEELLGNSSAAAPRAGKKRQPRPAKYKFTDV
                     NGETKTWTGQGRTPKPIAQALAEGKSLDDFLI"
     gene            complement(621..1145)
                     /gene="ygaP"
                     /locus_tag="RHX21_004891"
     CDS             complement(621..1145)
                     /gene="ygaP"
                     /locus_tag="RHX21_004891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase YgaP"
                     /protein_id="HDV1989925.1"
                     /translation="MALTTISPHDAQELIARGAKLIDIRDADEYLREHIPEADLAPLS
                     VLEQSGLPPKLRREQIIFHCQAGKRTSNNADKLAAIAAPAEIFLLEDGIDGWKRAGLP
                     VAVNKSQPLPLMRQVQIAAGGLILIGVVLGYTVNSGFFLLSGFVGAGLLIAGISGFCG
                     MARLLDKMPWNQQA"
     gene            complement(1155..1454)
                     /locus_tag="RHX21_004892"
     CDS             complement(1155..1454)
                     /locus_tag="RHX21_004892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDV1989926.1"
                     /translation="MTELAQLQASAEQAAALLKAMSHPKRLLILCMLSGSPGTSAGEL
                     TRITGLSASATSQHLARMRDEGLIDNQRDAQRILYSIKNEAVNAIIATLKNVYCP"
BASE COUNT          414 a          337 c          347 g          399 t
ORIGIN      
        1 tggctaatat ataatcttga aattattctg agagtttcag aaaataacag ctgaaataat
       61 ctcgcgcagg actgtaaata gattaaattt tgtggaaata taataagtga tcgcttacac
      121 tacgcgacga aatacttttt tgttttggcg ttaaaaggtt ttctttatta tgtccgtaat
      181 gttacaaagt ttaaataaca ttcgcaccct ccgtgcgatg gctcgcgaat tctccattga
      241 cgttcttgaa gaaatgctcg aaaaattcag gggtgtcact aaagaaagac gtgaagaaga
      301 agaacagcag cagcgtgaac tggctgagcg tcaggaaaaa attagcacct ggctggagct
      361 gatgaaagct gacggaatta acccggaaga gttattgggt aatagctctg ctgctgcacc
      421 acgtgctggt aaaaaacgcc agccgcgtcc ggcgaaatat aaattcactg atgttaacgg
      481 tgaaactaaa acctggaccg gtcagggccg tacaccgaag ccaattgctc aggcgctggc
      541 agaaggtaaa tctctcgacg atttcctgat ctaattactg aggccggatg tcgctgctag
      601 ggcgcgtccg gcgtcgcttc tcaagcttgt tggttccacg gcatcttatc taacaacctt
      661 gccattccac aaaaaccgct gattcctgca atcagtaacc cggcaccaac aaagccactt
      721 aataagaaga aaccgctatt tacggtataa cccagtacaa cgccgattaa tattaaacca
      781 cccgcagcga tctgcacctg gcgcattaac ggcaagggtt gagatttatt taccgctact
      841 ggcaatccag ctcttttcca gccatcaatc ccatcttcga gtaaaaatat ttctgcgggg
      901 gcggcaatcg ctgctaattt atcggcgtta ttactggtgc gtttacctgc ctggcagtgg
      961 aatataattt gctcgcgacg taatttaggt ggaagacctg actgttccag cacggataat
     1021 ggagccagat ctgcttcagg aatatgttca cgaagatatt catcagcgtc acgaatatcg
     1081 attaactttg cgccgcgtgc gattaattct tgtgcatcat gcggcgaaat ggttgtcaaa
     1141 gccatagtga ctccttacgg acaatagaca tttttcaggg tggcgataat ggcatttacc
     1201 gcctcatttt taatggaata tagaatgcgt tgggcatccc gttggttgtc gataagccct
     1261 tcgtcccgca tacgagcgag atgctgtgat gtcgcagagg cactcagtcc ggtaatgcgc
     1321 gtcagctctc ccgcgctggt gccgggggaa ccgctaagca tgcacagaat cagcaatcgt
     1381 ttaggatggc tcattgcttt caataaggcc gctgcctgtt cggcactggc ctgtaattgc
     1441 gcgagttcag tcatatttat ttaagtattt tctaaattaa gtaaattcta aactaaa
//
LOCUS       DAPGUL010000296         1488 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.302, whole genome shotgun sequence.
ACCESSION   DAPGUL010000296 DAPGUL010000000
VERSION     DAPGUL010000296.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1488
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.302"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            823..1425
                     /gene="fimB"
                     /locus_tag="RHX21_004893"
     CDS             823..1425
                     /gene="fimB"
                     /locus_tag="RHX21_004893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria switch DNA invertase FimB"
                     /protein_id="HDV1989927.1"
                     /translation="MKNKADNKKRNFLTHSEIESLLKAANTGPHAARNYCLTLLCFIH
                     GFRASEICRLRISDIDLKAKCIYIHRLKKGFSTTHPLLNKEVQALKNWLSIRTSYPHA
                     ESEWVFLSRKGNPLSRQQFYHIISTSGGNAGLSLEIHPHMLRHSCGFALANMGIDTRL
                     IQDYLGHRNIRHTVWYTASNAGRFYGIWDRARGRQRHAVL"
BASE COUNT          440 a          264 c          328 g          456 t
ORIGIN      
        1 tttgcaagct aactcagtga gcttggtgaa aataagtgtt tacccgccat caggctgagc
       61 ataattctca tcatgaaata tgtttcttgg tttgtggctt gtaactggtc actcctgatg
      121 tcgatctgga gaggcttgtt gatgctggtg ttttcaggat gatgtttcaa ttagtttgtt
      181 tgccatatcg cccggcgagt agctgtgatt gaggagggtt taagtcgtag tgaccaaagc
      241 catatttacc aacggatgta gatgaaaaag cgtcgcctgc gttcccccat atctccagga
      301 taaaaaggaa tgtaacaatc tcatgaccta aactgacgaa ccagctagca ataatcgcta
      361 gggacctaag aattagcttg ataatagcca ctaagaaatt actgcgttcc atgaaatagc
      421 cattttgtgg taaatggagt tgactaataa tgtcatatgt gagacggcta gttgaacgaa
      481 tattaaattt tgctgaattt tttatgttga ttttacttgt tacagaacat atcacatgat
      541 atatagataa gattagttgc attaatgatg agggttatta ttagattcgt atccgattga
      601 taaatatata aaggtacata gcatgcaaga gcatggcgtt tgtatggcaa agttattata
      661 agtaactatc gctactccat ttaagttcac tcagaagaac tggtccactt acgttagtta
      721 ttaagcaaac gttcgctttt ataaacataa tcaggataaa aatgttggat tattgctaac
      781 ccagcacagc tagtgcgcgt ctgtaattct aagggaaaaa cgatgaagaa taaggctgat
      841 aacaaaaaaa ggaacttcct gacccatagt gaaatcgaat cactccttaa agcagcaaat
      901 accgggcctc atgcagcacg taattattgt ctgactttgc tttgttttat tcatggtttc
      961 cgggcgagtg aaatttgtcg attgaggatt tcggatattg atcttaaggc aaagtgtata
     1021 tatatccatc gattaaaaaa aggcttttca acaacgcatc cgctattgaa caaagaagtt
     1081 caggctttaa aaaactggtt gagtatccgt acttcgtacc cgcatgctga gagcgagtgg
     1141 gtatttttat ctcgtaaggg aaatccgctt tctcggcaac agttttacca tattatctcg
     1201 acttccggtg gtaatgccgg gttgtcactg gagattcatc cgcacatgtt acgccattcg
     1261 tgtggttttg ctttggcgaa tatgggaata gatacgcgac ttatccagga ttatcttggg
     1321 catcgcaata ttcgtcatac tgtctggtat accgccagca atgcagggcg tttttacggc
     1381 atctgggata gagccagagg acgacagcgt cacgctgttt tatagagata gttgagatac
     1441 cagggatggt gtttaaaact acattattct tacgatatat caaaaatg
//
LOCUS       DAPGUL010000297         1462 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.303, whole genome shotgun sequence.
ACCESSION   DAPGUL010000297 DAPGUL010000000
VERSION     DAPGUL010000297.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1462
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.303"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..1403
                     /gene="betT"
                     /locus_tag="RHX21_004894"
     CDS             <1..1403
                     /gene="betT"
                     /locus_tag="RHX21_004894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="choline BCCT transporter BetT"
                     /protein_id="HDV1989928.1"
                     /translation="IGVVQLNYGLSVLFDIPDSMAAKAALIALSVIIATISVTSGVDK
                     GIRVLSELNVALALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPV
                     EWMNNWTLFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGN
                     SALYEIIHGGAAFAEEAMVHPERGFYSLLAQYPAFTFSASVATITGLLFYVTSADSGA
                     LVLGNFTSQLKDINSDAPGWLRVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFSF
                     VIFFVMAGLYKSLKVEDYRRESANRDTAPRPLGLQDRLSWKKRLSRLMNYPGTRYTKQ
                     MMETVCYPAMEEVAQELRLRGAYVELKSLPPEEGQQLGHLDLLVHMGEEQNFVYQIWP
                     QQYSVPGFTYRARSGKSTYYRLETFLLEGSQGNDLMDYSKEQVITDILDQYERHLNFI
                     HLHREAPGHSVMFPDA"
BASE COUNT          283 a          374 c          435 g          370 t
ORIGIN      
        1 gtatcggtgt ggtgcagctt aactatggct tgagcgtact gtttgatatt cccgattcga
       61 tggcggcaaa agcggcactg atcgccttgt cggtgataat cgccacgatc tctgtcacct
      121 ccggtgtcga taaggggatt cgtgtgttat cggaacttaa cgttgcgctg gcgctgggat
      181 tgatcctgtt cgtattgttt atgggcgaca cctcgttcct gcttaatgcg ctggtgctga
      241 atgttggcga ctatgtgaat cgctttatgg gcatgacgct caacagtttt gccttcgacc
      301 gtccagttga gtggatgaat aactggacgc tcttcttctg ggcatggtgg gtggcatggt
      361 cgccgtttgt cggcttgttc ctggcgcgta tctcgcgtgg gcgtaccatt cgccagttcg
      421 tgctgggcac gttgattatt ccgtttacct tcacgctgtt atggctctcg gtgttcggca
      481 atagcgcgct gtatgaaatc atccacggcg gcgcggcatt tgccgaggaa gcgatggtcc
      541 atccggagcg cggcttctac agcctgctgg cgcagtatcc ggcgtttacc tttagcgcct
      601 ccgtcgccac cattactggc ctgctgtttt atgtgacctc ggcggactcc ggtgcgctgg
      661 tgctggggaa tttcacctcg cagcttaaag atatcaacag cgacgccccc ggctggctgc
      721 gcgtcttctg gtcggtggcg attggcctgc tgacgctcgg catgctgatg accaacggga
      781 tatccgcgct gcaaaacacc acggtgatta tggggctgcc gttcagcttt gtgatcttct
      841 tcgtgatggc ggggttgtat aaatctctga aggtagaaga ttaccgccgt gaaagtgcca
      901 accgcgatac cgcgccgcga ccgctggggc ttcaggatcg cctgagctgg aaaaaacgtc
      961 tctcgcgcct gatgaattat ccgggcacgc gttacactaa acagatgatg gagacggtct
     1021 gttacccggc aatggaagaa gtggcgcagg agctgcggtt gcgcggcgcg tacgtggagc
     1081 taaaaagcct gccgccggaa gagggacaac agttggggca tctggatttg ttggtgcata
     1141 tgggcgaaga acaaaacttt gtctatcaga tttggccgca gcaatattcg gtgccgggct
     1201 ttacctaccg cgcacgtagc ggtaaatcga cctactaccg gctggaaacc ttcctgttag
     1261 aaggcagcca gggcaacgac ctgatggact acagcaaaga gcaggtgatc accgatattc
     1321 ttgaccagta cgagcggcac cttaacttta ttcatctcca tcgtgaagcg ccgggccata
     1381 gcgtgatgtt cccggacgcg tgattgttat tgcataaaac cgcgccatgt ctgcatatgg
     1441 cgcgggaatc attgactcgc tg
//
LOCUS       DAPGUL010000298         1447 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.304, whole genome shotgun sequence.
ACCESSION   DAPGUL010000298 DAPGUL010000000
VERSION     DAPGUL010000298.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1447)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1447)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1447
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.304"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..853
                     /locus_tag="RHX21_004895"
     CDS             <1..853
                     /locus_tag="RHX21_004895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989929.1"
                     /translation="GLLKPSSTRSVILETPPNVCMESRNSYENKIDEISSLSESKEHP
                     IDIQEKKDAFVNEFKGVLFDKNTRSSELLFNFYECCYKFLPRAQPQDKIDSYNSALQA
                     FSIFCSSTLTHNNIGFDFKLFPEVKLSGEHLETVFKYKNGDDVREIAKINITLQKEEG
                     GLYNLRGLDFKGCFFSGQNFSNYDIQYVNWGTSLFDVDTPCIFNAPAYNKSNEKSLKP
                     VSENGLSGVLTDRNNKIKLITGVAPFDDILFMDDDFDDSSSEDDPVENSPVVTSPVVS
                     SSKSSFQ"
     gene            1208..1426
                     /locus_tag="RHX21_004896"
     CDS             1208..1426
                     /locus_tag="RHX21_004896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000340076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDV1989930.1"
                     /translation="MKKLVRTLSAVDARVVCKPNRLGRSMWHLVVLLEELCKRGINFR
                     ALAQSIFAQQWGDECCKSKTICDLKVIV"
BASE COUNT          441 a          240 c          316 g          450 t
ORIGIN      
        1 tggtttactt aagccaagta gtacgcgtag tgttatttta gaaacgccgc caaatgtctg
       61 tatggaatca cgtaattcat atgaaaacaa aatagatgag atttcatctt tgtcagagtc
      121 aaaggaacac cccatagata ttcaagaaaa aaaagatgcg tttgtgaatg agttcaaggg
      181 ggtattattt gataaaaata caaggtcttc agagcttctg tttaattttt atgagtgttg
      241 ctataagttt ttaccaagag ctcagcctca agataaaatc gatagctata attcagcact
      301 gcaagctttt tccatttttt gttcatctac gttgacacat aataatatag gctttgattt
      361 caaattattt cctgaagtca agctgtctgg agaacatctt gaaacggtat tcaaatacaa
      421 aaatggcgat gatgtccggg agatagccaa aattaacatt actctccaaa aagaagaggg
      481 tggtttatat aatttacgtg gattggattt taaggggtgc ttcttttctg gacagaactt
      541 cagtaactat gatattcaat atgtgaactg gggaacgtca ttgtttgatg ttgatactcc
      601 gtgtattttt aatgcgcctg cttacaacaa gagtaatgaa aaatcattaa aacctgtgag
      661 cgaaaacggt ttaagtggag tattgactga tcgtaataat aaaataaaac tcatcacggg
      721 cgtggcacca ttcgatgata ttttatttat ggatgatgac tttgatgata gttcctctga
      781 ggatgatccc gttgagaata gtcctgttgt gactagtccc gttgtatcaa gttctaaaag
      841 cagttttcaa tgattaataa atggcaattt ttacaaagag ataataacgt agattgaaac
      901 aatatgtatt attgattgag taaacgggat tattcttcac actacatcca ttttagtgtc
      961 actaccaaag aaaaaggggc tacgttttca tgtaacccct tgatttattt ggtgggctgg
     1021 cagtgactga attggtgctg taattggttg aaatatttca tctaatgtct ggttcaactt
     1081 tccttagctg cctgaaagtt ttttgatctt acccagcaat aacagcgtta cggtgcacca
     1141 cgcctgactg aagaactgcg tgctcagggt taccacttca acgtaaaacc gtggcaggag
     1201 gtccggactg aaaaaactgg tcaggacatt atcggcggtg gacgcacggg tagtctgtaa
     1261 accgaaccga ctggggcgca gtatgtggca tcttgtcgtg ctgttggagg agctgtgcaa
     1321 acgtggtatt aactttcgtg ctctggccca atctatattt gcccaacaat ggggggacga
     1381 atgctgtaaa agtaaaacaa tctgcgatct caaagttatt gtgtgatttt tatgtgagca
     1441 gaagata
//
LOCUS       DAPGUL010000299         1430 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.305, whole genome shotgun sequence.
ACCESSION   DAPGUL010000299 DAPGUL010000000
VERSION     DAPGUL010000299.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1430
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.305"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            360..575
                     /gene="essD"
                     /locus_tag="RHX21_004897"
     CDS             360..575
                     /gene="essD"
                     /locus_tag="RHX21_004897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage lysis protein EssD"
                     /protein_id="HDV1989931.1"
                     /translation="MKSMDKLTTGVAYGTSAGSAGYWFLQLLDKVTPSQWAAIGVLGS
                     LVFGLLTYLTNLYFKIKEDKRKAARGE"
     gene            575..1069
                     /gene="rrrD"
                     /locus_tag="RHX21_004898"
     CDS             575..1069
                     /gene="rrrD"
                     /locus_tag="RHX21_004898"
                     /EC_number="3.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme RrrD"
                     /protein_id="HDV1989932.1"
                     /translation="MPPSLRKAVAAIGGGAIAIASVLITGPSGNDGLEGVSYIPYKDI
                     VGVWTVCHGHTGKDIMLGKTYTKAECKALLNKDLATVARQINPYIEVDIPETTRGALY
                     SFVYNVGADNFRTSTLLRKINQGDIKGACDQLRRWTYAGGKQWKGLMTRREIEREICL
                     WGQQ"
     gene            1286..>1430
                     /gene="rzoD"
                     /locus_tag="RHX21_004899"
     CDS             1286..>1430
                     /gene="rzoD"
                     /locus_tag="RHX21_004899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prophage lysis lipoprotein RzoD"
                     /protein_id="HDV1989933.1"
                     /translation="MRKLKMMLCVMMLPLVVVGCTSKQSVSQCVKPPPPPAWIMQPPP
                     DWQT"
BASE COUNT          378 a          314 c          345 g          393 t
ORIGIN      
        1 ttctataatt cagcagttta atttaaatca actaaaaata acgtctgaaa ttatttattg
       61 gttatttgtt gaggttttct tatgtatttg tggtggtgtt ttgaacactc ggtagcattc
      121 tcataaatat cattcagtgg tttacgtacg taaaaaattg gttatgctgt taagagtggt
      181 tacttcgtca cacagcttaa acccgccgtc gagctggttt ttccattttt tgagtctcga
      241 tattagctga taactcaata cctgagttat tcactgactc cgagtctgtt acgtttctgc
      301 ttttttgcga tacgttgtat tccctcaatt tacacccgct ttgtctgcga ggtggggtta
      361 tgaaatccat ggataagtta acaacgggtg tcgcctatgg cacctcagca ggtagtgccg
      421 gttactggtt tttacagctg ctcgataaag tcacgccctc acagtgggca gcaataggtg
      481 tgctgggtag cctggtattt ggcctgctga cgtacctgac aaacctttat ttcaagatta
      541 aagaagataa gcgcaaggct gcgagaggtg aataatgcct ccatcattac gaaaagccgt
      601 tgctgctatt ggtggcggag caattgctat agcatcagtg ttaatcactg gcccaagtgg
      661 taacgatggt ctggaaggtg tcagctacat accatacaaa gatattgttg gtgtatggac
      721 tgtatgtcac gggcatacag gaaaagacat catgctcggt aaaacgtata ccaaagcaga
      781 atgcaaagca ctcttgaata aagaccttgc cactgtcgcc agacaaatta acccgtacat
      841 cgaagtcgat ataccggaaa caacgcgcgg cgctctttac tcattcgttt acaacgtggg
      901 tgctgacaat ttcagaacat cgacgcttct tcgcaaaata aaccagggcg atatcaaagg
      961 cgcatgtgat cagctacgtc gctggacata tgctggcggt aagcaatgga aaggtctcat
     1021 gactcgtcgt gagattgagc gtgaaatctg tttgtggggt cagcaatgaa cagagtaacc
     1081 gcgattatct ccgctctggt tatctgcatc atcgtctgcc tgtcatgggc tgttaatcat
     1141 taccgtgata acgccattac ctacaaagcc cagcgcgaca aaaatgccag agaactgaag
     1201 ctggcgaacg cggcaattac tgacatgcag atgcgtcagc gtgatgttgc tgcgctcgat
     1261 gcaaaataca cgaaggagtt agctgatgcg aaagctgaaa atgatgctct gcgtgatgat
     1321 gttgccgctg gtcgtcgtcg gttgcacatc aaagcagtct gtcagtcagt gcgtgaagcc
     1381 accaccgcct ccggcgtgga taatgcagcc tccccccgac tggcagacac
//
LOCUS       DAPGUL010000300         1352 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.306, whole genome shotgun sequence.
ACCESSION   DAPGUL010000300 DAPGUL010000000
VERSION     DAPGUL010000300.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1352
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.306"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(1..1011)
                     /gene="tssI"
                     /locus_tag="RHX21_004900"
                     /pseudo
     CDS             complement(1..1011)
                     /gene="tssI"
                     /locus_tag="RHX21_004900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310087.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
BASE COUNT          329 a          365 c          345 g          313 t
ORIGIN      
        1 ccgctccctg ccgtcctggc accgcctgtg gctgttcgcc gtgcagttca cttgccacca
       61 cctgccattc ccggttcagg ttcgcctgcg gatgccccgt cagcacaatt cgtcgtcccg
      121 gccatatctc cggcgagcga ctcattcccc gcgcggtttc tgcattgttt cgccagccgt
      181 ccatctgcca gcgggcaaag ttctgcccgt gggcaccctt gaaacgtccg gggtagtcat
      241 acacttcata ctgcgtgcgc tggtaatcct ggtactggcc ttcctgatca aaacgccctg
      301 cccagccggg tcgtttaaag gtgtagtcct tggtcaccac ggaagaaggg cggatttgtg
      361 cgctgtagcg gaactggctg atgcagaggg tgctcacctc ggtacgggtg ttcggattcc
      421 aggggatctc aaaggactcc ggcagataac gcacggtgtc gcacaggacc aggctctggt
      481 cggtactttt tgcgcgtgct cctcataaaa gaagatgcct tcctccgccg ccatccggca
      541 caggaaatcg taatcggttt cgccgtactg gacacaaaac tcacgggaag gatgcggctc
      601 gctgaacagc ggactccact cggtcacacc gttttccttc aggatcgtag cgaggatgct
      661 ttcgatgtcc tcattctgga agatacggaa gttctggcgc agccctgtgc gccacagcgg
      721 cgggcacacc ttcatgctgt acagcatctg gtttttgtcg ttctccccca gttcaaacca
      781 ggtcaccaca cctttcaccc ggcgctgtac gtcatcgccc tgccataccg tcaggtaggc
      841 cattttgtcc agcacctgcg caaattcaag ggaaagaaac tgctgactga ccagagaaag
      901 gtcgagggaa aaaagtgaag agagtgactg ggtgagatga aaggaaacca ccgcaaacgc
      961 gtccggtggc aggccgtcca cttcaagtgt gaaacgtaat ccggttgaca tagcaacctc
     1021 cgtgaaaatg aataataatc cgcacatatt gcatgtacaa catgtcgggc ggatgagata
     1081 agcgagtcga catctggcgt taccggggaa tatcagaaaa atgtcatggt tatgtgatga
     1141 tttagtctgg gattttactt cagagaaacg ggtgtctgtt tagtcaacaa aataatcaca
     1201 aacgcaacgg atgggttctc gacgttattc acgacaggct cgtacattac agcgagtaat
     1261 aaaaaacctg atatgcaaag tcaaaccaat attcataatg tctttttatt cacaacaata
     1321 aataattcaa taacaatcat tgaaatgaat ga
//
LOCUS       DAPGUL010000301         1340 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.307, whole genome shotgun sequence.
ACCESSION   DAPGUL010000301 DAPGUL010000000
VERSION     DAPGUL010000301.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1340
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.307"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            958..>1340
                     /locus_tag="RHX21_004901"
     CDS             958..>1340
                     /locus_tag="RHX21_004901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016230784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989934.1"
                     /translation="MVQKILSDKVMNERTNAYYSYYLGERNISVLPLNVYDPPERFIA
                     YIKKNRENLNITLSDFELEQIISGMRLKALAFLIPLEKISWIAGSERACLFSWYLLMQ
                     FIQNNRAKISADLLQKNKLYLKEEYL"
BASE COUNT          376 a          295 c          263 g          406 t
ORIGIN      
        1 acggcagcaa gccagtaatg ggttaagtga taacaggtgt ctggaaatat aggggcaaat
       61 ccactgtgga agagactcac tcagcctgca ggatattctt tccggcatcc gggaatgtcc
      121 gcctgaatgc aaacaggatg atatttgaat ccgtaatact gttctttcat cataaataat
      181 ttatgcagat acagttaacc gttacagtag ccggtttgtt ttaccgggaa ataatatccg
      241 tcagactgat accggaacat atctgaaaca cgttatgatt ttttgttatc agaaatgttg
      301 tatattctta tccgtggcga cagtttaatg ccctctggta tcacctgata atgtatatcc
      361 tgcgatgatt cgttatattt acgggacacg cctcttttca ttgtgctcct tttcagactt
      421 cattttccgt aagtgttccc cggcataaag gaggtacctt tctggcgttt ataactctct
      481 ttatcggtga cgccggtaat acagggaata ccacaccgac aaacgaggta ttaacagacg
      541 atatttcagt gtccataatt tttctgtccg gttaaataac gtcagtctgc tgccctctga
      601 ctgtaatcat caaagccgga atgcataccg ggttacaacg taaaaaaagt gatgctggcc
      661 cccggtgcag ctggcgggcg aaacatgttt acctttcaat accccctgtc tgcagtctcc
      721 actcttccat cctcttaagc tacgtcggcc acatgagtgc acttccatga taacaggtat
      781 tcctgtcagc ataacgaagc cggttacctt cccttcctcc tgcatttcct gtcagaatga
      841 ctatacagcg cgcagattgc ctttttattg accatcttaa tataccgtta taaacttctt
      901 tttatcatat tattatcacc ttattatgtt taatttttaa gcagccggag aaagaggatg
      961 gttcagaaaa ttttgtcgga taaggttatg aatgaaagaa caaatgcgta ttactcttat
     1021 tatcttggag agcgtaatat ctccgtactg ccccttaatg tttatgatcc cccggaacgt
     1081 tttatcgctt acataaaaaa aaacagagaa aatctgaaca tcacactttc agattttgaa
     1141 cttgaacaaa taatctctgg tatgcgtctg aaggccctgg ccttcctgat ccccctggaa
     1201 aaaatatcct ggatcgcggg cagtgaacgc gcatgcttat tttcctggta tctgttgatg
     1261 cagtttatcc agaataacag ggcaaaaata agcgcagact tgcttcaaaa gaataaactg
     1321 tatcttaaag aagagtatct
//
LOCUS       DAPGUL010000302         1340 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.308, whole genome shotgun sequence.
ACCESSION   DAPGUL010000302 DAPGUL010000000
VERSION     DAPGUL010000302.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1340)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1340)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1340
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.308"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..1331
                     /locus_tag="RHX21_004902"
     CDS             <1..1331
                     /locus_tag="RHX21_004902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HDV1989935.1"
                     /translation="TVLVSLLFGLALVLVNSWFNQPGVEEVVPRSTYLMVMIALFFID
                     TVAFIFMQLYFIYDRRQFSNCILSLAFLSCLIYFVKTVIIIQQIIEGRLTSSVVQNDI
                     AIYYLFRQMSLCILIFLALVNKVSENTKQRNLFSKKMTLCISLFFVFGGPIVAHILSS
                     HYESYNLHIAELTNENGQVVWKASYVTIMIFMWLTLLSVNLYFNGLRYDIWNGVTVIA
                     FCAVLYNISLLFMSRYSVSTWYISRTIEVVSKLTVMVIFMCHIFSALRVTKNIAHRDP
                     LTNIFNRNYFFNELTVQSASAKKTPYCVMIMDIDHFKKVNDTWGHPVGDQVIKTVVNI
                     IGKSIRPDDLLARVGGEEFGVLLTDIDTERAKALAERIRENVERLTGDNPEYAIPQKV
                     TISIGAVVTQENTLNPNEIYRLADNALYEAKETGRNKVVVRDVVNFCESP"
BASE COUNT          375 a          216 c          302 g          447 t
ORIGIN      
        1 gtactgtatt agtgagctta ttgtttgggc ttgctttggt tttggtgaat agttggttta
       61 atcagccagg cgttgaggaa gttgttccac gatcaaccta tctgatggta atgattgctt
      121 tattttttat cgatactgtt gcatttattt ttatgcagtt gtatttcatt tatgaccgta
      181 ggcaattttc aaactgtata cttagtttgg cttttctgag ttgtttgatt tactttgtta
      241 aaaccgtcat tatcattcag caaattattg aggggcgttt gacaagcagt gttgtccaaa
      301 atgacattgc aatctattat ttgtttcgtc agatgagttt gtgcatatta atatttctgg
      361 cattggtgaa taaagttagt gaaaacacaa aacagcgcaa tttattttcc aaaaaaatga
      421 ctttgtgcat aagtttgttt tttgtttttg gggggccgat agttgctcac atactttcta
      481 gtcattatga gagctacaat ttacacattg ccgagttaac caatgaaaat ggtcaggtgg
      541 tttggaaagc ctcatatgtt accataatga ttttcatgtg gttaaccttg ctttcggtta
      601 atctatactt taatggttta cgctatgata tctggaatgg agtgacggtg attgcttttt
      661 gtgccgtact gtacaatatc tctctgttat ttatgagtag gtatagcgtg tccacttggt
      721 atattagtcg cactattgaa gtagtcagta agttaactgt tatggtaata tttatgtgcc
      781 atatattcag tgcgctacga gtaacaaaga acattgcaca tcgcgatccc ttaaccaata
      841 tatttaacag aaattatttt tttaatgaac tgacagttca atcagcatca gccaaaaaaa
      901 cgccttattg cgtcatgatt atggatatcg accacttcaa aaaagtcaac gacacctggg
      961 ggcatccggt tggcgatcag gtgataaaaa cagtggtgaa tatcattggg aaaagcatac
     1021 gaccagatga ccttttagcg cgcgtcggcg gcgaagagtt tggcgtcttg ctgacggaca
     1081 tcgatactga acgtgcgaaa gctttagcgg aaaggattcg ggaaaatgtt gagcgtttaa
     1141 ctggcgataa tcctgaatac gctataccac aaaaagtgac gattagtatt ggcgctgttg
     1201 tgactcagga aaatacgtta aacccaaatg agatctatcg actggctgat aacgcacttt
     1261 acgaggcgaa agagaccggg cgtaataagg tggttgtgag ggatgtggtg aatttttgtg
     1321 agtcaccata aagcggcatt
//
LOCUS       DAPGUL010000303         1332 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.309, whole genome shotgun sequence.
ACCESSION   DAPGUL010000303 DAPGUL010000000
VERSION     DAPGUL010000303.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1332)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1332)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1332
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.309"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..250)
                     /locus_tag="RHX21_004903"
     CDS             complement(<1..250)
                     /locus_tag="RHX21_004903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989936.1"
                     /translation="MADKAILWALISASNKEGRKACSLSYFACKAAEAELGLAYMAAN
                     DNKEFLTSLSNIMRYKIDAGLSESYTCYLLSKGKIIRPY"
     gene            complement(957..1331)
                     /locus_tag="RHX21_004904"
     CDS             complement(957..1331)
                     /locus_tag="RHX21_004904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001449246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HDV1989937.1"
                     /translation="MMGSTAMTYDLSEEKLMKLKYKSQHGDSEASFRLYQYYCFTKNN
                     IDKQLRFLERSASQGNVTAQFNYGVFLSDTNPTLSEYYNLNRAIYWMEFAVNNGNIDA
                     KSKLQELKKLKRMDRRKNKENP"
BASE COUNT          393 a          277 c          217 g          445 t
ORIGIN      
        1 gatatggtct tatgatcttt cccttactta ataaatagca tgtataggat tcggaaagtc
       61 cagcatctat tttgtacctc attatattag ataaggatgt gagaaattcc ttgttatcat
      121 tcgcagccat atatgccagt ccgagttcag cctctgcggc cttacaggca aaatagctta
      181 gtgaacacgc ttttcgtccc tctttattac tggctgatat tagtgcccat aatattgctt
      241 tgtctgccaa atctaactct ctctgaaatt gtcttgcagt aactgcactc gcagaaatag
      301 agaaaaaaat acaattgtta ataaccttgc catatttttt agtccgtaac tgttaatgtg
      361 ctatctggct ctgaaaatat taactcattt aatttttgca tgtcattaga taaaccagtt
      421 atacaaccct cggaacagaa tcgaggtcct aaagacggac caaaagcgtt taaacaacta
      481 tgtattgaaa atccattgcg attataagtt cctgtattaa ctgacggtac taatcgtatg
      541 ccgtcaggtt ttctattgct tgctcccggg tcattaacat tccaactcca taggccttga
      601 ggtattggcc atctatttat aaatgtgtac aacggggatt atttttacat tgcatattat
      661 taccagaagc gactggaata ctaagcacat cataaaaatt atcatcacat ggtatatctg
      721 aaacacacga aagcatacct aaagttatac tgtataaaca ggtggctaat cccaagggga
      781 tcgattccag aaatcgggtt caacggatac tgataaaaat tccacctacc ttccagccca
      841 atcggagcct gagtgttata ccgcccctgc tgcggttaat gttaccgata atagttatag
      901 tacagccctg attcatcatc atactactgc tgcggcagtc tgatgaacta ttgcttttac
      961 ggattctcct tattcttcct tctatccatt cgctttagct ttttgagctc ttgaagtttg
     1021 ctctttgcat caatattacc gttatttaca gcgaattcca tccaataaat agctctattc
     1081 aaattataat attctgataa tgttggattt gtatctgata aaaagacccc ataattaaac
     1141 tgcgctgtaa cattcccctg agatgctgat ctttccaaga atcgcaattg tttatcaata
     1201 ttatttttag taaagcagta atattgatat agtcgaaatg atgcctctga atcaccatgt
     1261 tgtgatttat acttcagttt catcagcttt tcttcactta aatcataggt cattgctgta
     1321 gatcccatca ca
//
LOCUS       DAPGUL010000304         1289 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.310, whole genome shotgun sequence.
ACCESSION   DAPGUL010000304 DAPGUL010000000
VERSION     DAPGUL010000304.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1289
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.310"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..249
                     /locus_tag="RHX21_004905"
     CDS             <1..249
                     /locus_tag="RHX21_004905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lyase"
                     /protein_id="HDV1989938.1"
                     /translation="EMLQDKNEEVRIEAIIGLSYRKDKRVLSVLCDELKKNTVYDDII
                     EAAGELGDKTLLPVLDTMLYKFDDNEIITSAIDKLKRS"
     gene            277..1235
                     /locus_tag="RHX21_004906"
                     /pseudo
     CDS             277..1235
                     /locus_tag="RHX21_004906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312497.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
BASE COUNT          378 a          253 c          323 g          335 t
ORIGIN      
        1 gagatgcttc aggataaaaa tgaggaagtc cgtattgaag caataatcgg actttcctac
       61 agaaaagata aaagggtttt atctgtttta tgcgatgagt taaaaaaaaa tactgtttat
      121 gatgatatca ttgaagctgc gggtgaatta ggtgataaaa cgctacttcc tgttttagat
      181 actatgttgt acaagtttga tgacaatgaa attataactt ccgctattga taagctgaag
      241 cgttcatagc gtgagttgcc tatgcacagt gggggattcc cgccggcacg gtgcagatgc
      301 tcgaccggct ggaaagtgaa atcctggctg accgggtgag tgaggaaagc cgccgctggc
      361 tggcatcgtg cggcctgacc gtggagcaga tgaaaaacca gatggacccg gtgtacacgc
      421 cggcgcgaaa aatccacctg taccactgcg accatcgcgg cctgccgctg gcgctcatca
      481 gcacggaagg ggcaacagcg tggtgcgcag aatatgatga atggggcaac ctgctgagtg
      541 atgagaaccc gcatcatctg cagcagctca ttcgcctgcc gggtcagcag tatgatgagg
      601 agtccggcct gtattacaac cgccaccgct attatgaccc gctgcagggg cggtatatca
      661 ctcaggatcc gattgggctg aaggggggat ggaattttta tcagtatccg ttgaatccgg
      721 tcataaatgt agatccgcaa ggtttggttg atataaattt ataccccgaa agtgatctta
      781 tccattctgt agctgatgag attaatatcc caggcgtttt cacaatcggg gggcatggta
      841 cccccacatc tattgaatcc gcaacgcgca gtatcatgac agctaaagat ctagcatatc
      901 taattaaatt tgatgggaat tataaagatg ggatgacagt ttggttattt tcttgtaata
      961 caggtaaagg acaaaattca tttgctagcc aattagctaa agagttacat acaaatgtaa
     1021 taggacctga cacgctatgg acgtggtggg ggcgaggaac taatggtaag ttaaaaatgg
     1081 atacagtgct aacagcacca acgaacctta attcaaataa ggatctaatg gctataacaa
     1141 caaaagacct tggtaattgg ataacatatg ggccatctgg gcaccccatt tctaatatgc
     1201 aaggtacgcc agaaaaaccc agtgatataa gataggttgt agatgtatga aagcatgctt
     1261 gttactattt ttttattttt cttttattt
//
LOCUS       DAPGUL010000305         1289 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.311, whole genome shotgun sequence.
ACCESSION   DAPGUL010000305 DAPGUL010000000
VERSION     DAPGUL010000305.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1289)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1289)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1289
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.311"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..134)
                     /locus_tag="RHX21_004907"
     CDS             complement(<1..134)
                     /locus_tag="RHX21_004907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989939.1"
                     /translation="MIYITIFMILPCPVPCSHVFLYVFYIFLFLVLFIMTIYQSSQKL
                     "
     gene            215..1289
                     /locus_tag="RHX21_004908"
                     /pseudo
     CDS             215..1289
                     /locus_tag="RHX21_004908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000027427.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
BASE COUNT          472 a          176 c          306 g          335 t
ORIGIN      
        1 tgaagttttt gactggattg gtaaatggtc ataatgaaca acaccagaaa gagaaaaata
       61 taaaatacat acagaaagac atgagagcaa gggacggggc agggcaagat catgaaaatt
      121 gtgatgtaaa tcacgatttt catcttggct ttaacgccta caggtgatca aaatttaacc
      181 tttggaataa ctaaaaagat aaaaaaggac ccaggtgagt attcaaagtt tgcttgatta
      241 tatttcagtg atccctgata tacgacaaca aggaaaggtt aaacataaat tatctgctat
      301 tttgtttctc accgtatgtg cagtaattgc aggtgccgat gagtggcagg aaattgaaga
      361 ttttggacat gaaagacttg aatggctaaa gaaatatggt gattttgata atggcattcc
      421 ggtcgatgac accattgcac gcgttgtgag taacattgac agtttggcct ttgaaaagat
      481 gtttattgaa tggatgcagg agtgccatga aatcactgat ggtgaaatta tagcaataga
      541 tggaaagacc ataagaggct cctttgataa gggaaaaaga aaaggagcaa tccatatggt
      601 gagtgcattc tcgaacgaaa atggtgttgt actggggcag gtgaaaacgg aagccaaaag
      661 taatgagatt acagccattc cagagttgct taacctactg tatttaaaga aaaatttgat
      721 aacaattgat gctatgggct gtcagaaaga tatcgcttcg aagatcaaag ataaaaaagc
      781 agattatctt ctggcagtaa aaggcaatca ggggaaatta catcatgcat tcgaggaaaa
      841 atttcctgta aatgtgtttt ctaattataa aggcgattcg tttagtacgc aggagataag
      901 tcatggaaga aaagaaacac gtttgcatat tgtcagtaac gtaacgcctg aacttttgtg
      961 attttgaatt cgaatggaag ggattaaaaa agctttgtgt agcattgtca ttcaggcaga
     1021 agaaagaaga taaatcagca gaaggtgtaa gcatccgata ttatatttca tcaaaggata
     1081 tggatgctaa agaatttgca catgctatca gagcgcactg gctgatcgag cacagtcttc
     1141 attgggtgtt agatgtaaaa atgaatgaag atgccagccg gataagaaga ggaaacgcag
     1201 cctaaataat atctggaata aagaagatgg cactgaattt attaagagat tgcaaagaca
     1261 ttaagggtga agaggaaaag aaagaaggc
//
LOCUS       DAPGUL010000306         1287 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.312, whole genome shotgun sequence.
ACCESSION   DAPGUL010000306 DAPGUL010000000
VERSION     DAPGUL010000306.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1287
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.312"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            87..>1287
                     /locus_tag="RHX21_004909"
     CDS             87..>1287
                     /locus_tag="RHX21_004909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001339197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4-like element ISVsa5 family transposase"
                     /protein_id="HDV1989940.1"
                     /translation="MCELDILHDSLYQFCPELHLKRLNSLTLACHALLDCKTLTLTEL
                     GRNLPTKARTKHNIKRIDRLLGNRHLHKERLAVYRWHASFICSGNTMPIVLVDWSDIR
                     EQKRLMVLRASVALHGRSVTLYEKAFPLSEQCSKKAHDQFLADLASILPSNTTPLIVS
                     DAGFKVPWYKSVEKLGWYWLSRVRGKVQYADLGAENWKPISNLHDMSSSHSKTLGYKR
                     LTKSNPISCQILLYKSRSKGRKNQRSTRTHCHHPSPKIYSASAKEPWILATNLPVEIR
                     TPKQLVNIYSKRMQIEETFRDLKSPAYGLGLRHSRTSSSERFDIMLLIALMLQLTCWL
                     AGVHAQKQGWDKHFQANTVRNRNVLSTVRLGMEVLRHSGYTITREDSLVAATLLTQNL
                     FTHGYVLG"
BASE COUNT          391 a          313 c          255 g          328 t
ORIGIN      
        1 tttatcaaaa tcattaagtt aaggtagata cacatcttgt catatgatca aatggtttcg
       61 ccaaaaatca ataatcagac aacaaaatgt gcgaactcga tattttacac gactctcttt
      121 accaattctg ccccgaatta cacttaaaac gactcaacag cttaacgttg gcttgccacg
      181 ccttacttga ctgtaaaact ctcactctta ccgaacttgg ccgtaacctg ccaaccaaag
      241 cgagaacaaa acataacatc aaacgaatcg accgattgtt aggtaatcgt cacctccaca
      301 aagagcgact cgctgtatac cgttggcatg ctagctttat ctgttcgggc aatacgatgc
      361 ccattgtact tgttgactgg tctgatatcc gtgagcaaaa acggcttatg gtattgcgag
      421 cttcagtcgc actacacggt cgttctgtta ctctttatga gaaagcgttc ccgctttcag
      481 agcaatgttc aaagaaagct catgaccaat ttctagccga ccttgcgagc attctaccga
      541 gtaacaccac accgctcatt gtcagtgatg ctggctttaa agtgccatgg tataaatccg
      601 ttgagaagct gggttggtac tggttaagtc gagtaagagg aaaagtacaa tatgcagacc
      661 taggagcgga aaactggaaa cctatcagca acttacatga tatgtcatct agtcactcaa
      721 agactttagg ctataagagg ctgactaaaa gcaatccaat ctcatgccaa attctattgt
      781 ataaatctcg ctctaaaggc cgaaaaaatc agcgctcgac acggactcat tgtcaccacc
      841 cgtcacctaa aatctactca gcgtcggcaa aggagccatg gattctagca actaacttac
      901 ctgttgaaat tcgaacaccc aaacaacttg ttaatatcta ttcgaagcga atgcagattg
      961 aagaaacctt ccgagacttg aaaagtcctg cctacggact aggcctacgc catagccgaa
     1021 cgagcagctc agagcgtttt gatatcatgc tgctaatcgc cctgatgctt caactaacat
     1081 gttggcttgc gggcgttcat gctcagaaac aaggttggga caagcacttc caggctaaca
     1141 cagtcagaaa tcgaaacgta ctctcaacag ttcgcttagg catggaagtt ttgcggcatt
     1201 ctggctacac aataacaagg gaagactcac tcgtggctgc aaccctgctt actcaaaatc
     1261 tattcacaca tggttacgtt ttgggga
//
LOCUS       DAPGUL010000307         1277 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.313, whole genome shotgun sequence.
ACCESSION   DAPGUL010000307 DAPGUL010000000
VERSION     DAPGUL010000307.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1277)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1277)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1277
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.313"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..825
                     /gene="ldtC"
                     /locus_tag="RHX21_004910"
     CDS             <1..825
                     /gene="ldtC"
                     /locus_tag="RHX21_004910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707028.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase LdtC"
                     /protein_id="HDV1989941.1"
                     /translation="HVVENDGGSLEAIAKKYNVGFLALLQANPGVDPYVPRAGSVLTI
                     PLQTLLPDAPREGIVINIAELRLYYYPPGKNSVTVYPIGIGQLGGDTLTPTMVTTVSD
                     KRANPTWTPTANIRARYKAQGIELPAVVPAGPDNPMGHHAIRLAAYGGVYLLHGTNAD
                     FGIGMRVSSGCIRLRDDDIKTLFSQVTPGTKVNIINTPIKVSAEPNGARLVEVHQPLS
                     EKIDDDPQLLPITLNSAMQSFKDAAQTDAEVMQHVMDVRSGMPVDVRRHQVSPQTL"
     gene            complement(908..1165)
                     /gene="bhsA"
                     /locus_tag="RHX21_004911"
     CDS             complement(908..1165)
                     /gene="bhsA"
                     /locus_tag="RHX21_004911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple stress resistance protein BhsA"
                     /protein_id="HDV1989942.1"
                     /translation="MKNVKTLIAAAILSSMSFASFAAVEVQSTPEGQQKVGTISANAG
                     TNLGSLEEQLAQKADEMGAKSFRITSVTGPNTLHGTAVIYK"
BASE COUNT          333 a          311 c          317 g          316 t
ORIGIN      
        1 catgtggtgg aaaatgacgg tggttctctg gaagccatcg ccaaaaaata taacgtcggc
       61 tttctcgctc tgttacaggc taaccctggc gttgatcctt acgtaccgcg cgcgggtagc
      121 gtgttaacga tcccgttgca aaccctactt ccagatgcgc cgcgcgaagg cattgtgatc
      181 aatattgcgg agctgcgtct ctattactac ccgccgggta aaaattcggt aaccgtgtat
      241 ccaataggta ttggtcagtt aggtggtgac acgctgacac cgacaatggt gaccaccgtt
      301 tcagacaaac gtgcaaaccc aacctggacg ccaacggcaa acatccgcgc ccgttataaa
      361 gcacagggaa ttgagttgcc tgcggtagtg ccggctggac cggataaccc aatgggccat
      421 catgcgattc gtctggcggc ctatggcggc gtttatttgc ttcacggtac gaacgccgat
      481 ttcggcattg gcatgcgggt aagttctggc tgtattcgtc tgcgggatga cgatatcaaa
      541 acactcttta gccaggtcac cccaggcacc aaagtgaata tcatcaacac tccgataaaa
      601 gtctctgccg aaccaaacgg tgcgcgtctg gttgaagtac atcagccgct gtcagagaag
      661 attgatgacg atccgcagct gctgccaatt acgctgaata gcgcaatgca atcatttaaa
      721 gatgcagcac aaactgacgc tgaagtgatg caacatgtga tggatgtccg ttccgggatg
      781 ccggtggatg tccgccgtca tcaagtgagc ccacaaactc tgtaaatcct ggataaaaaa
      841 aatccccgcg acacggcatg tcgcggggaa aaaatcagca gtagcaggca ttaatgaggg
      901 ttaatgctta tttataaatt actgctgttc catggagggt attcggaccg gttacagaag
      961 taatacggaa agattttgcg cccatctcat ccgctttttg cgccagctgc tcttccagcg
     1021 atcccagatt tgtccccgcg ttagcactga ttgtaccgac tttttgttgg ccttctggcg
     1081 ttgactgaac ttcgacagcc gcaaagctgg caaatgacat ggagcttaaa atcgccgcag
     1141 cgatgagggt ttttacgttt ttcataatag tggccttatg cagatgaatg acgtcgcaag
     1201 caattactta acgatcgata actaaatgat agatgtgatc tggatcacat acaagatatt
     1261 ttttataaca atcatta
//
LOCUS       DAPGUL010000308         1241 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.314, whole genome shotgun sequence.
ACCESSION   DAPGUL010000308 DAPGUL010000000
VERSION     DAPGUL010000308.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1241)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1241)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1241
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.314"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            173..1153
                     /locus_tag="RHX21_004912"
     CDS             173..1153
                     /locus_tag="RHX21_004912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110-like element IS621 family transposase"
                     /protein_id="HDV1989943.1"
                     /translation="MEHELHYIGIDTAKEKLDVDVLRPDGRHRTKKFANTTKGHDELV
                     SWLKGHKIDHAHICIEATGTYMEPVAECLYDAGYIVSVINPALGKAFAQSEGLRNKTD
                     TVDARMLAEFCRQKRPAAWEAPHPLERALRALVVRHQALTDMHTQELNRTETAREVQR
                     PSIDAHLLWLEAELKRLEKQIKDLTDDDPDMKHRRKLLESIPGIGEKTSAVLLAYIGL
                     KDRFAHARQFAAFAGLTPRRYESGSSVRGASRMSKAGHVSLRRALYMPAMVATSKTEW
                     GRAFRDRLAANGKKGKVILGAMMRKLAQVAYGVLKSGVPFDASRHNPVAA"
BASE COUNT          305 a          304 c          369 g          263 t
ORIGIN      
        1 agagaaaatc ggccagtttt ctctgcctgc agtccgcatg ccgtatcggg ccttgggttc
       61 taacctgttg cgtagattta tgcagcggac tgcctttctc ccaaagtgat aaaccggaca
      121 gtatcatgga ccggttttcc cggtaatccg tatttgcaag gttggtttca ctatggaaca
      181 tgaacttcat tatatcggta tcgacaccgc taaagagaaa ctggatgtcg atgtgttgcg
      241 tcctgatggt cgtcatcgca ccaaaaaatt cgctaacacc actaaagggc acgatgagct
      301 ggtgagctgg ctgaaaggtc acaagattga ccatgcgcat atctgcatcg aagcgaccgg
      361 cacctatatg gaacctgtcg ctgagtgcct ttacgatgct ggctacatag tgtcagtcat
      421 taatcctgcg ctgggtaaag ctttcgctca gagtgaagga ctgcgtaaca agactgatac
      481 cgtggatgcg cgcatgctgg cagagttctg tcgtcagaag cgccctgcag cctgggaagc
      541 gcctcacccg cttgaacgcg cgttgcgtgc cctggtagtc cgccaccagg cgctgacaga
      601 tatgcacacg caggaactga atcgcactga aacggcgcgg gaagtccaga gaccgagcat
      661 tgatgctcac cttctgtggc ttgaagcaga gctgaagcgt cttgagaagc agataaaaga
      721 cctgacagac gatgatccgg atatgaaaca ccgcaggaaa ctgctggaaa gcatcccggg
      781 tatcggagag aaaacatctg cggtattgct ggcttatatc ggtctgaagg accgcttcgc
      841 ccatgccaga cagttcgccg cttttgcggg tctgacacca cggcgttatg aatcaggtag
      901 cagtgtgaga ggggcgagcc ggatgagtaa ggccggacat gtgtcgcttc gcagggcgtt
      961 gtatatgccc gcaatggtag ccaccagtaa gactgagtgg ggacgggcgt tccgcgaccg
     1021 tctggcggct aatggcaaga aaggaaaggt gattctcggc gcgatgatgc gcaagctggc
     1081 acaggtggcg tatggagtgc tgaagtcagg cgtgccgttc gatgcgtcac ggcataatcc
     1141 ggtagcggcg taaaaatcgc ggaagggatg aaaaaaacag cgcctgacgg cgctgtgtct
     1201 ggcatgcctg caatccggga aaccggacca ggaaaaaact t
//
LOCUS       DAPGUL010000309         1235 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.315, whole genome shotgun sequence.
ACCESSION   DAPGUL010000309 DAPGUL010000000
VERSION     DAPGUL010000309.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1235
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.315"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            46..1143
                     /gene="ompC"
                     /locus_tag="RHX21_004913"
     CDS             46..1143
                     /gene="ompC"
                     /locus_tag="RHX21_004913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpC"
                     /protein_id="HDV1989944.1"
                     /translation="MKKLTVAISAVAASVLMAMSAQAAEIYNKDSNKLDLYGKVNAKH
                     YFSSNDADDGDTTYARLGFKGETQINDQLTGFGQWEYEFKGNRAESQGSSKDKTRLAF
                     AGLKFGDYGSIDYGRNYGVAYDIGAWTDVLPEFGGDTWTQTDVFMTGRTTGVATYRNN
                     DFFGLVDGLNFAAQYQGKNDRSDFDNYTEGNGDGFGFSATYEYEGFGIGATYAKSDRT
                     DTQVNAGKVLPEVFASGKNAEVWAAGLKYDANNIYLATTYSETQNMTVFADHFVANKA
                     QNFEAVAQYQFDFGLRPSVAYLQSKGKDLGVWGDQDLVKYVDVGATYYFNKNMSTFVD
                     YKINLLDKNDFTKALGVSTDDIVAVGLVYQF"
BASE COUNT          352 a          271 c          273 g          339 t
ORIGIN      
        1 cagtgacatc attttttaat aatagttcaa aaaaaagggc tcacgatgaa aaaattaaca
       61 gtggcaattt ctgctgtagc tgcatcagta ctgatggcga tgtctgctca ggcagctgaa
      121 atttataata aagacagtaa caagctggat ctgtacggga aagttaatgc caagcactac
      181 ttctcctcta atgatgcaga tgatggtgat actacttatg cccgtcttgg cttcaaaggt
      241 gaaacccaaa tcaacgatca actgactggt ttcggtcagt gggaatatga attcaaaggc
      301 aaccgcgctg aatctcaagg ttcctccaaa gacaaaaccc gtcttgcatt tgcaggcctg
      361 aaattcggtg actacggctc aatcgattac ggccgtaact acggtgtagc atacgacatc
      421 ggtgcgtgga ctgacgttct gccagaattc ggtggcgata cctggaccca aacagatgtg
      481 ttcatgactg gtcgcaccac tggtgttgca acctatcgta acaacgactt ctttggtctg
      541 gttgatggtc tgaactttgc tgctcagtac caaggcaaaa acgatcgtag cgatttcgat
      601 aactacactg aaggtaacgg tgatggcttc ggtttctctg ctacctatga atacgaagga
      661 ttcggtatcg gtgcaactta tgcgaaatct gatcgtaccg acactcaagt taatgcaggg
      721 aaagttcttc ctgaagtatt tgcttccggt aaaaatgcag aagtttgggc cgcaggtctg
      781 aaatatgacg ctaacaacat ttacctggcc actacctatt ctgaaaccca gaatatgact
      841 gtatttgctg atcacttcgt tgctaataaa gcccaaaact tcgaagctgt tgcacaatat
      901 cagttcgatt tcggtctgcg tccgtccgtt gcttacctgc aatctaaagg taaggatctt
      961 ggagtatggg gcgatcagga cttagtcaaa tatgttgatg taggtgcaac ctattacttc
     1021 aacaaaaata tgtctacttt cgttgattac aaaatcaacc tgcttgacaa aaatgacttc
     1081 actaaagcac tcggtgtaag cactgatgac atcgttgctg taggtctggt ttaccagttc
     1141 taatctgatt acgaaaaaga tatgttgcgg gaggcgttgc ctccccaaca tataagtggc
     1201 tccctcaagc cacttccttt agaagcacaa ccttg
//
LOCUS       DAPGUL010000310         1216 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.316, whole genome shotgun sequence.
ACCESSION   DAPGUL010000310 DAPGUL010000000
VERSION     DAPGUL010000310.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1216
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.316"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..508)
                     /gene="sfmF"
                     /locus_tag="RHX21_004914"
     CDS             complement(<1..508)
                     /gene="sfmF"
                     /locus_tag="RHX21_004914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria assembly protein"
                     /protein_id="HDV1989945.1"
                     /translation="MRRALFSCFCGLLWISSGWAADPLGTININLHGNVVDFSCTVNT
                     ADIDKTVDLGRWPTTQLLNAGDTTALVPFSLRLEGCPPGSVAILFTGTPASDTNLLAL
                     DDPAMAQTIAIELRNSDRSRLALGAASPTEEVDANGNVTLNFFANYRALASGVRPGVA
                     KADAIFMIN"
     gene            complement(519..>1216)
                     /gene="fimH"
                     /locus_tag="RHX21_004915"
     CDS             complement(519..>1216)
                     /gene="fimH"
                     /locus_tag="RHX21_004915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415066.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type 1 fimbrin D-mannose specific adhesin FimH"
                     /protein_id="HDV1989946.1"
                     /translation="LGAMSLVDSVMDIQFPPQNYIRMGTDPNVSQNLPFGVMDSRLIF
                     RLKVIRPFINMVEIPRQVMFTVYVTSTPYDPLVTPVYTISFGGRVEVPQNCELNAGQI
                     VEFDFGDIGASLFSAAGPGNRPAGVMPQTKSIAVKCTNVAAQAYLTMRLEASAVSGQA
                     MVSDNQDLGFIVADQNDTPITPNDLNSVIPFRLDAAAAANVTLRAWPISITGQKPTEG
                     PFSALGYLRVDYQ"
BASE COUNT          336 a          323 c          273 g          284 t
ORIGIN      
        1 aattgatcat aaatatcgca tccgctttcg ccacacctgg ccgaacaccg ctggctaacg
       61 ctcgataatt ggcaaaaaag tttagtgtga cattgccatt tgcatctact tcctcagtcg
      121 ggctcgccgc tcccagtgcg agccgggagc gatcgctatt acgtaattcg atggcgatgg
      181 tttgcgccat tgcgggatca tccagagcca gcaggttggt atcggatgcc ggcgttcccg
      241 taaataaaat cgcaactgaa cccggaggac atccctccag ccgcaggcta aaagggacga
      301 gtgccgtggt atcgccagcg ttcagtaatt gtgtcgtagg ccatctgcct aaatctaccg
      361 tcttatcaat atccgcagtg tttacggtac aggagaaatc aacaacgtta ccgtgcaaat
      421 tgatattaat cgttcccaaa gggtcagctg cccatccact ggaaatccac agtaacccgc
      481 agaaacagct aaagagtgct cttctcattc tccgtacctc attgataatc gacgcgtaaa
      541 taccccagcg cgctaaacgg cccttcggtc ggtttttgac cggtaatact gataggccag
      601 gcgcgaagtg tgacattggc tgccgcagct gcatccagac ggaaaggaat aacgctattg
      661 agatcgttag gcgtgatcgg cgtatcgttc tgatcggcga caataaaacc taaatcctga
      721 ttgtccgaca ccatcgcctg accagaaacg gcactggctt ccagacgcat tgttaaataa
      781 gcctgcgcag caacattcgt acatttgacc gcaatgctct tggtttgcgg catgacacca
      841 gcaggtcgat tacccggccc tgccgcacta aataacgatg cgccgatatc accaaaatca
      901 aattcaacaa tctgcccggc atttaattcg cagttttgcg gtacttcaac ccggccacca
      961 aaactaatgg tataaacagg tgtaaccaac ggatcgtaag gcgttgatgt cacatacacg
     1021 gtaaacatca cctgtctggg gatctccacc atgttaataa agggacgaat aacctttaaa
     1081 cgaaatatta aacgagaatc catcaccccg aatggaaggt tttgtgaaac gttaggatct
     1141 gttcccatcc gaatataatt ttgcgggggg aactgaatat ccatcacact atcaaccaga
     1201 ctcatcgcac ctaata
//
LOCUS       DAPGUL010000311         1187 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.317, whole genome shotgun sequence.
ACCESSION   DAPGUL010000311 DAPGUL010000000
VERSION     DAPGUL010000311.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1187
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.317"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            1..>1187
                     /locus_tag="RHX21_004916"
     rRNA            1..>1187
                     /locus_tag="RHX21_004916"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          336 a          260 c          365 g          226 t
ORIGIN      
        1 aagcgactaa gcgtacacgg tggatgccct ggcagtcaga ggcgatgaag gacgtgctaa
       61 tctgcgataa gcgtcggtaa ggtgatatga accgttataa ccggcgattt ccgaatgggg
      121 aaacccagtg tgattcgtca cactatcatt aactgaatcc ataggttaat gaggcgaacc
      181 gggggaactg aaacatctaa gtaccccgag gaaaagaaat caaccgagat tcccccagta
      241 gcggcgagcg aacggggagg agcccagagc ctgaatcagt gtgtgtgtta gtggaagcgt
      301 ctggaaaggc gcgcgataca gggtgacagc cccgtacaca aaaatgcaca tgctgtgagc
      361 tcgatgagta gggcgggaca cgtggtatcc tgtctgaata tggggggacc atcctccaag
      421 gctaaatact cctgactgac cgatagtgaa ccagtaccgt gagggaaagg cgaaaagaac
      481 cccggcgagg ggagtgaaaa agaacctgaa accgtgtacg tacaagcagt gggagcacag
      541 agcaatctgt gtgactgcgt accttttgta taatgggtca gcgacttata ttctgtagca
      601 aggttaaccg aataggggag ccgaagggaa accgagtctt aactgggcgt taagttgcag
      661 ggtatagacc cgaaacccgg tgatctagcc atgggcaggt tgaaggttgg gtaacactaa
      721 ctggaggacc gaaccgacta atgttgaaaa attagcggat gacttgtggc tgggggtgaa
      781 aggccaatca aaccgggaga tagctggttc tccccgaaag ctatttaggt agcgcctcgt
      841 gaattcatct ccgggggtag agcactgttt cggcaagggg gtcatcccga cttaccaacc
      901 cgatgcaaac tgcgaatacc ggagaatgtt atcacgggag acacacggcg ggtgctaacg
      961 tccgtcgtga agagggaaac aacccagacc gccagctaag gtcccaaagt catggttaag
     1021 tgggaaacga tgtgggaagg cccagacagc caggatgttg gcttagaagc agccatcatt
     1081 taaagaaagc gtaatagctc actggtcgag tcggcctgcg cggaagatgt aacggggcta
     1141 aaccatgcac cgaagctgcg gcagcgacgc ttatgcgttg ttgggta
//
LOCUS       DAPGUL010000312         1187 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.318, whole genome shotgun sequence.
ACCESSION   DAPGUL010000312 DAPGUL010000000
VERSION     DAPGUL010000312.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1187)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1187)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1187
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.318"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            23..550
                     /locus_tag="RHX21_004917"
     CDS             23..550
                     /locus_tag="RHX21_004917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001335846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HDV1989947.1"
                     /translation="MKGGWNFYQYPLNPVQYIDSMGLASKYGHLNNGGYGARPNKPPT
                     PDPSKLPDIAKQLRLPYPIDQASSAPNVFKTFFRVLSPYDYTLYCRKWVKPNLTCTPQ
                     DDSQYPGMDTKTASDYLPQTNWPTTQLPPGYTCAEPYLFPDINKPDGPATAGIDDLGE
                     ILAKMKQRTSRGIRK"
     gene            547..1116
                     /locus_tag="RHX21_004918"
     CDS             547..1116
                     /locus_tag="RHX21_004918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989948.1"
                     /translation="MKRVLFFLLMIFVSFGVIADCEIQAKDHDCFTIFAKGTIFSAFP
                     VLNNKAMWRWYQNEDIGEYYWQTELGTCKNNKFTPSGARLLIRVGSLRLNENHAIKGT
                     LQELINTAEKTAFLGDRFRSYIRAGIYQKKSSDPVQLLAVLDNSIMVKYFKDEKPTYA
                     RMTAHLPNKNESYECLIKIQHELIRSEEK"
BASE COUNT          406 a          212 c          251 g          318 t
ORIGIN      
        1 tatcactcag gatccgattg ggctgaaggg gggatggaat ttttatcagt atccgctgaa
       61 tccggttcag tatatagatt caatgggact ggcatcaaaa tatggacact taaataatgg
      121 cggatatgga gcgagaccca acaaaccgcc tacgcccgat ccaagtaaat tgccggacat
      181 agcgaaacaa ttaagactgc catatcctat tgaccaggcc agtagtgcgc ctaatgtttt
      241 caaaacattc ttcagagtat taagccctta cgactacaca ctgtattgca ggaagtgggt
      301 aaaaccaaat ctgacttgta cgccacagga tgattcccag tatccaggga tggatacaaa
      361 gacagcaagt gattacctgc cacagacaaa ttggccaaca actcaattac caccaggata
      421 tacttgtgca gaaccctatt tattcccaga cattaataaa cccgatgggc cagcaacagc
      481 agggatagat gatttgggtg aaattttagc taaaatgaaa cagagaacat cgagaggaat
      541 aagaaaatga aaagagtttt gttctttttg ctgatgatat ttgttagttt tggtgttata
      601 gctgattgcg aaatacaagc taaagatcat gattgtttta ctattttcgc taagggtact
      661 attttttccg cgtttcctgt cttaaataat aaagccatgt ggagatggta tcagaatgag
      721 gacatcggtg agtattattg gcaaacagaa ctgggtacat gtaaaaataa taaattcaca
      781 ccaagcgggg cgagactctt aattcgcgtc gggtcactac gccttaatga aaatcatgcc
      841 atcaaaggaa cgttgcagga gttgataaat acagcagaaa aaacggcgtt tctcggcgat
      901 cggtttagaa gttatataag agcgggtatc tatcaaaaaa agagcagtga tccagttcag
      961 ttgttggcag tccttgataa ttcaatcatg gtaaaatatt ttaaagatga gaaaccaact
     1021 tatgctcgaa tgacagcaca tctcccgaac aaaaatgagt cttacgaatg tttaataaag
     1081 atacagcatg aactaattcg tagtgaagag aaataaaatc tcttcctgag aaaacaaatt
     1141 aatcattgtg aaaaattata taactcatgg aataggtgtt tattttg
//
LOCUS       DAPGUL010000313         1138 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.319, whole genome shotgun sequence.
ACCESSION   DAPGUL010000313 DAPGUL010000000
VERSION     DAPGUL010000313.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1138
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.319"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            233..784
                     /gene="sfaX"
                     /locus_tag="RHX21_004919"
     CDS             233..784
                     /gene="sfaX"
                     /locus_tag="RHX21_004919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011478152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator SfaX"
                     /protein_id="HDV1989949.1"
                     /translation="MRACTQTVCFSNMENNEMNNTDTLEKIIRHQKNKDPAYPFQEHL
                     LMQLCIRANKRMQDNISEFLGAYGINHSVYMVLTTLFTAESHCLSPSEISQKLQFTRT
                     NITRITDFLEKTGYVKRTDSREDRRAKKISLTSEGMFFIQRLTLAQSMYLKEIWGYLT
                     HDEQELFEVINKKLLAHLDDVSS"
BASE COUNT          359 a          217 c          257 g          305 t
ORIGIN      
        1 tggatatctg ggatgccccg ggaagtcacc tttcagacgg gcggagggct ggtgaattat
       61 ccgcgattac tgagcagtat ggataatcct ttttcacaga cttgtcagca gccagcattt
      121 atgttctttt atctgaggga atttatctgt ctgctgtgtc ggaatatctc agttatacag
      181 aaatcaggca ggaataaatt gtagtggaaa gtcgatgttt accggatgac tgatgcgcgc
      241 ttgtactcag acagtgtgtt tcagtaatat ggagaataat gaaatgaata acacagacac
      301 attagaaaaa ataatcagac accaaaaaaa caaagacccc gcatatccct ttcaggagca
      361 tttgttgatg caactctgta ttcgcgcaaa taaaaggatg caggataata tatctgaatt
      421 tctgggggcg tatggaataa atcactcagt gtacatggtt ctcaccacat tattcacagc
      481 ggagagtcat tgtctgtcac cttcagagat aagccagaaa ctgcagttta ccagaactaa
      541 tattacccgc attacagatt ttttagaaaa aaccggatat gtaaaaagga cggatagcag
      601 ggaggatcgc cgtgctaaaa aaatcagtct gacatctgaa ggtatgtttt ttattcagag
      661 gctcactctt gcacaaagca tgtatctgaa agaaatctgg ggttatctga cccatgatga
      721 acaggaactg tttgaagtca ttaataaaaa attactggcg catcttgatg atgtcagctc
      781 ataaagcgtg aaatgcctga gtatgccgga tagcttcagg caaaagaata atgattcttg
      841 cagacgtgtt tttccggata caaaaaaaat gataaaaatt gcagcgccag gcatctttca
      901 aagcagggag acctgtaccg cgtcgaaaat ttcagccagt taatatcatt gtctgaacca
      961 ggcacttcgc ccgggcagga gaagaagcgt ggttgcggtc atcctgtgta ctgaagtcgt
     1021 tatgaaggaa aaatacaaat aattgcccat tttctctgta caatagtaag cgtaaactga
     1081 ccgccgtatg tagccattaa gccagtattg gtaacgtagg tgcccacttt ttcaactg
//
LOCUS       DAPGUL010000314         1125 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.320, whole genome shotgun sequence.
ACCESSION   DAPGUL010000314 DAPGUL010000000
VERSION     DAPGUL010000314.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1125
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.320"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(152..715)
                     /gene="ipbA"
                     /locus_tag="RHX21_004920"
                     /gene_synonym="fimX"
     CDS             complement(152..715)
                     /gene="ipbA"
                     /locus_tag="RHX21_004920"
                     /gene_synonym="fimX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_060710320.1"
                     /note="IpbA is also known as HbiF and FimX; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase IpbA"
                     /protein_id="HDV1989950.1"
                     /translation="MTRKYLTQDEVYRLMDAAQSMSFPERNRCLIMMAFIHGFRASEL
                     LDLRLSDIDASGKQLNIRRIKNGFSTTHPLLPDEYNLIKLWLKQRKLIENGVEGDWLF
                     LSRKRRPISRQHFFSIIREAGKRAGLAVKAHPHMLRHACGFALADNGVDTRLLQDYLG
                     HRNIQHTVRYTASNAARFKGVWKKKPR"
     gene            961..1094
                     /locus_tag="RHX21_004921"
                     /pseudo
     CDS             961..1094
                     /locus_tag="RHX21_004921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_303089.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          339 a          186 c          221 g          379 t
ORIGIN      
        1 ttgtggttaa tcatttcaaa tcatggggtt attttacttt agcgagaaat atcaacatgt
       61 tatgtgtttt atttaattga atgggctgtt tttttatgga agaattgagg aaaacgtagg
      121 aatctgacat tttgaatcag aaggtactgt tttaacgagg cttttttttc cacacccctt
      181 taaaacgagc agcattactg gctgtgtatc tgacagtatg ctgaatattt cgatgaccca
      241 gataatcctg aagtagtcgg gtatcgacac cattgtcagc cagagcaaaa ccacaggcat
      301 gacgtaacat atgaggatgt gcttttacag ctaatcctgc acgttttcca gcctcacgaa
      361 tgatagaaaa aaaatgttgt ctgctgatag ggcggcgttt ccgggagaga aaaagccagt
      421 ctccttcaac tccgttttca attaacttcc tctgcttaag ccacaacttg atcaaattat
      481 attcatcagg aagaagagga tgtgttgtcg agaaaccatt tttaatacgc cgaatattaa
      541 gttgttttcc agatgcatca atatcggata aacgtaaatc aagaagttca ctggccctaa
      601 aaccgtgaat gaaagccatc ataattagac agcgatttct ttcaggaaag gacatactct
      661 gggctgcatc catcagcctg tagacttcat cctgtgtgag atattttctc gtcatacgcc
      721 accgtgtaca gttttaaaaa aaagagaggc acacccagat aagtatgcct gcaatcagaa
      781 cgttatcgat gtaatctcat tatctcatta ttaaaatttt ttgaatagta gttctacgca
      841 acagattaaa tatgaactat ttattgtgca gcttttctac aagtcatttt taatgcgtgt
      901 ttttatctac agtgatgtga gaaaataaat ataaaagcta tgaactacag ggcgtggggg
      961 atgtgtgtta cgtctaatct tttagtgatg tttagtagtt ttgagatatt tgacgttatt
     1021 tcttatgagg ttgtttttat tattatctta ttggttttat atgcattttg tcgttctgtg
     1081 aagttagggt gtagaaaata aaaatttaat attattcccg ttaat
//
LOCUS       DAPGUL010000315         1123 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.321, whole genome shotgun sequence.
ACCESSION   DAPGUL010000315 DAPGUL010000000
VERSION     DAPGUL010000315.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1123)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1123)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1123
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.321"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            181..>1123
                     /locus_tag="RHX21_004922"
     CDS             181..>1123
                     /locus_tag="RHX21_004922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HDV1989951.1"
                     /translation="METGKIALCSAFIFLVLFAKNEMRTKIKFGKLILFASLATQLLF
                     FAHAMWQHFYLNVDRVALSASHATTAGYIILFPSLLASILILKSDLRHKTTLYTINFM
                     LSLCAVIVTETRAAILVFPFFALILIVMDSYINKRINYKLYCFITIALLAGVFSFKDT
                     LLMRMNDLNNDLVNYSHDNTRTSVGARLAMYEVGLKTYSPIGQSLEKRAEKIHELEEK
                     EPRLSGALPYVDSHLHNDLIDTLSTRGIPGVVLTILAFSAILIYALRTAKEPYILILL
                     FSLLVVGLSDVILFSKPVPTAVFITIILLCAYFKAQSD"
BASE COUNT          342 a          203 c          181 g          397 t
ORIGIN      
        1 cttcatgcag ctggaattat atctgcattg tattttcttg cgacaccaaa aaaaacaata
       61 actaataatc ctactttgtt aattttcatc tcattatgtc ttttgggtat cgtaaatatc
      121 atctggtatt cacattataa agtttcaggc tctgtttata ccaatgcata tcgtggccca
      181 atggaaactg gaaaaattgc cttgtgtagc gcttttattt tcttagttct ttttgctaaa
      241 aatgagatga gaacaaaaat aaaatttggg aaactaattc tgttcgcatc cctggcaacg
      301 cagttacttt tttttgcgca tgccatgtgg caacatttct atttaaacgt cgaccgtgtt
      361 gcattatcag cttcccacgc tacaacagca ggctacatca tcctttttcc ttctttactg
      421 gcatcaattc tcattttaaa atccgactta agacataaaa caacattata tacaattaac
      481 ttcatgctta gtttatgtgc tgtcatagta actgagacgc gtgcagccat attagtgttt
      541 ccattctttg cgttaatatt aatcgtaatg gatagttata ttaataagcg aattaattat
      601 aagttatatt gttttattac gattgcatta ttagcaggtg tattttcttt taaagataca
      661 ttgcttatga gaatgaatga cttaaataac gatttagtta attattcgca tgataacacc
      721 agaacttcag tcggtgcccg tctggcaatg tatgaagttg gcttaaaaac atattctcca
      781 ataggacaat cactggaaaa acgtgcggaa aaaatacatg aactagaaga aaaagagcct
      841 agattgagtg gcgctttacc ctatgtagat tctcatttgc ataacgatct catagatacg
      901 ttatcaacgc gtggtattcc tggagttgta ttaacaattt tagcattttc agcaatactc
      961 atatatgcct taagaactgc taaagaacct tatattttaa tcttgctttt ttcactactg
     1021 gtagtaggac taagtgatgt aatactcttt tctaaaccgg ttccgactgc tgtgtttatc
     1081 accataatat tgctttgtgc ttattttaaa gcacaatcgg acc
//
LOCUS       DAPGUL010000316         1109 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.322, whole genome shotgun sequence.
ACCESSION   DAPGUL010000316 DAPGUL010000000
VERSION     DAPGUL010000316.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1109
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.322"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..542
                     /locus_tag="RHX21_004923"
     CDS             <1..542
                     /locus_tag="RHX21_004923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISAs1-like element ISEc1 family transposase"
                     /protein_id="HDV1989952.1"
                     /translation="GRLNKAFEEKFPLKELNNPEHDSYAISEKSHGREEIRLHIVCDV
                     PDELIDFTFEWKGLKKLCVAVSFRSIIAEQKKEPEMTVRYYISSADLTAEKFATAIRN
                     HWHVENKLHWRLDVVMNEDDCKIRRGNAAELFSGIRHIAINILTNDKVFKAGLRRKMR
                     KAAMDRNYLASVLAGSGLS"
     gene            572..1024
                     /locus_tag="RHX21_004924"
     CDS             572..1024
                     /locus_tag="RHX21_004924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989953.1"
                     /translation="MLVGAAVGAVVIGGGIVIYNNREAVGDAIEKSMEMRGEAELLNA
                     QSQMEFWRDPYGAFSSVFGNDDSSKENPNVGKDLTDEEKNCLGSGSTGGSGGWEPDED
                     GEIRNTYRSIKDAPQYPRGVRNVQNGTTRNVVKDQQLLKQLRKVDSGK"
BASE COUNT          351 a          172 c          313 g          273 t
ORIGIN      
        1 aggggcggct aaataaagcc tttgaggaaa aatttccgct gaaagaatta aataatccag
       61 agcatgacag ttacgcaatt agtgaaaaga gtcacggcag agaagaaatc cgtcttcata
      121 ttgtttgcga tgtccctgat gaacttattg atttcacgtt tgaatggaaa gggctgaaga
      181 aattatgcgt ggcagtctcc tttcggtcca taatagcaga acaaaagaaa gagccagaaa
      241 tgacggtcag atattatatc agttctgctg atttaaccgc tgagaaattc gccacagcga
      301 tccgaaatca ctggcacgtg gagaataagc tgcactggcg tctggacgtg gtaatgaatg
      361 aagacgactg caaaataaga agaggaaatg cagcagaatt attttcaggg atacggcaca
      421 ttgctattaa tattttgacg aatgataagg tattcaaggc agggttaaga cgtaagatgc
      481 gaaaagcagc catggacagg aactatctgg cgtcagtcct tgcggggagc gggctttcgt
      541 aatcttgccc tgggtaggag gccctccagg gatgttagtc ggtgcggcag ttggagcggt
      601 ggttattggt ggtggtatag taatatacaa caatcgcgag gctgttgggg atgcgattga
      661 gaaaagtatg gagatgcggg gtgaagccga attattaaat gcacaaagtc aaatggaatt
      721 ctggcgagat ccctatggtg ctttttccag cgtgtttgga aatgatgatt catcaaaaga
      781 gaatccaaat gtcgggaagg atttgacgga tgaagagaag aactgtttgg gcagtggcag
      841 tacaggaggt tcgggagggt gggagccaga tgaggatggc gaaataagaa atacctacag
      901 gtctattaag gatgctcctc agtatcccag aggggttagg aatgtccaaa atggcactac
      961 aaggaatgtt gtaaaggatc agcagttatt gaaacaatta cgtaaagtag attcaggaaa
     1021 atagagtaaa gtttataaag atggatttga tgcgtcaggt cgaaaagtgt ccattcacta
     1081 ttttgaaagt cagagtggtc gagtattta
//
LOCUS       DAPGUL010000317         1017 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.323, whole genome shotgun sequence.
ACCESSION   DAPGUL010000317 DAPGUL010000000
VERSION     DAPGUL010000317.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1017
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.323"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..135
                     /locus_tag="RHX21_004925"
     CDS             <1..135
                     /locus_tag="RHX21_004925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDV1989954.1"
                     /translation="LRTWQKKEEVNTQNSQSLSLVEFEFLLLLAGEHPEYVLCKRESK
                     "
     gene            527..826
                     /locus_tag="RHX21_004926"
     CDS             527..826
                     /locus_tag="RHX21_004926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989955.1"
                     /translation="MKCSSVFTSTTNHVFTFERVTLCTIILMHKDTGQQYVVLFTDNN
                     KIRDYKTGIVPQFGELKQSDVDLVLFYRDEYEKYFDSLKDGDECLSFKDFIECLR"
BASE COUNT          297 a          201 c          227 g          292 t
ORIGIN      
        1 ctaagaacct ggcagaaaaa agaggaagtt aatactcaaa acagtcaaag tctgtcactg
       61 gttgagtttg agtttctttt gttacttgca ggagaacatc ctgaatacgt gctctgcaaa
      121 agggagtcaa aataaaatga cctgtgatgg ttttatatta gtacctggag ttgcgcccgt
      181 agctcgctga cgctcacacg cgcagtacag cgccccgtcc aggggaaccc tggacggcgt
      241 aaactcgctg gcgcgagcgc taactgcggc attctgcggc gcaaatcagc ataatcatgg
      301 cctgctggtc agttgggctt tgcagggtga agggatggcc tgtgctgccc tggtattttc
      361 gttcgcccct tccatccgct tacgcggatt aaaaacgtga taacaatcac ttatcgagta
      421 aaaaaacggg agaacacttg caaatacgac ttgaaagtcg tattattatt tcatcgaaag
      481 gggaatggcc cctctcacaa tagcccagca gggcaggaga tttaaaatga aatgctcatc
      541 tgtttttact tcaaccacta atcatgtttt cacattcgaa cgagtaacgc tttgcactat
      601 tatccttatg cataaggata cgggacaaca gtatgttgtc ctatttactg ataacaataa
      661 aattcgtgac tataaaaccg gaattgttcc tcagtttggc gaacttaagc agagtgatgt
      721 tgatttagtc cttttctaca gggacgaata tgaaaaatat tttgattcgt taaaagatgg
      781 cgatgaatgc ttgagtttta aagattttat tgagtgcctt cgttaagcat tataaatgca
      841 ggggggaacc ctgcattttc tggaaatttc aatattgatt ctgaaattgt ctattaacat
      901 caatgcaagg gaaattcatg aaaacgttaa aacaagccgc aatgcagttt gcatctgatc
      961 tgcgtaataa tcgctgtttt aaagctgctt ataatgatgc tctgttagag cttgatc
//
LOCUS       DAPGUL010000318         1016 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.324, whole genome shotgun sequence.
ACCESSION   DAPGUL010000318 DAPGUL010000000
VERSION     DAPGUL010000318.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1016)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1016)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1016
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.324"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            1..80
                     /locus_tag="RHX21_004927"
                     /pseudo
     CDS             1..80
                     /locus_tag="RHX21_004927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001426852.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
     gene            502..963
                     /locus_tag="RHX21_004928"
     CDS             502..963
                     /locus_tag="RHX21_004928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010349363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989956.1"
                     /translation="MSLALHGKSELELAAQKALELLDYVSDITTVDGKILAIMGLITG
                     LSGQAKVSHILFEQAKIHSTDIASLYYYRALVHFHNEKIEEARICIDKSLQLEPRRRK
                     AVVIKECVDMYVPNPLKNNIKLYYKETESESHRVIIDNILKLKQLTRICMR"
BASE COUNT          374 a          179 c          170 g          293 t
ORIGIN      
        1 caggaattag tgcaaatcat ttcaaataaa aaaatcgatg gtctctatac ctatccgatg
       61 gctgcgacaa atttttgtaa tgatcacata tctcaaaatt cattcttgag cagattcaag
      121 ccagattatt tcgttacagg aagaataaac cagaataatg cagtgaacac tttatacatt
      181 gagttgatcg acgctaaaaa ccttttcctc atcgccagta atcatctccc tgttgatgaa
      241 ctacataata catcacaatt tattatagat aatatccttc aaacggtaca taaaccagaa
      301 cgatctgtaa gattagctaa gcaggaccaa ggatataaga atcattattt atcagatgaa
      361 atgttagccg gaaagaaaga actttacgac ttcacccctg aaagcattta cagggccatg
      421 actatatttg atagattaca aaataaaagt gatatacaga cgctaaaaac agaatgttat
      481 tgccttctag cggaatgcca tatgtctttg gcacttcatg gaaaaagtga acttgaactt
      541 gctgctcaaa aagcattaga gcttttagat tatgtatcag acataaccac tgtcgatgga
      601 aaaattttag ctattatggg actgataact ggtctgtctg gacaagcaaa agtatctcat
      661 atcttatttg aacaggctaa gatacactca actgatatag cctctctcta ctactatagg
      721 gcactagtcc actttcataa tgaaaaaatt gaagaggcaa ggatttgtat agacaaatca
      781 ctacaactcg aacccagaag acgaaaagca gttgtgataa aagaatgtgt agatatgtat
      841 gtgcctaacc cgctcaaaaa caacattaaa ctctactata aagaaactga gagtgaaagc
      901 catcgagtta taattgacaa cattttgaaa ttaaagcagc tgacgagaat ttgtatgcga
      961 taaattttta ttgacgcaat tttattattt agatgtatgc aacttgttat ttaaac
//
LOCUS       DAPGUL010000319          983 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.325, whole genome shotgun sequence.
ACCESSION   DAPGUL010000319 DAPGUL010000000
VERSION     DAPGUL010000319.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 983)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 983)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..983
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.325"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(618..793)
                     /locus_tag="RHX21_004929"
                     /pseudo
     CDS             complement(618..793)
                     /locus_tag="RHX21_004929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612254.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          308 a          198 c          198 g          279 t
ORIGIN      
        1 aaataaccgt attaccagta atttttaccc attcagttat taagctctca ggtataagtg
       61 acttcaaaat acatagctac attattaaaa caagtgaata tccggaggag tttttttcca
      121 atgcagtatg gggtaaaaaa aatataaaac cgggggaata ttactctgtg caggctgttt
      181 ctatgtttac gacaaaccag tttattctcc tttgtcccaa ggatattata aggttttatc
      241 gggaaagctg gaagttcgac ctgcttaatg tagacttcga tacaaatacc aggaagaaac
      301 tccaggaaga agcagcatat tgcgtaccaa tttctgcaat atctgtaaaa cgatgggata
      361 tgcctcttca gggctcgaaa ccctcaaatt agaaggccgc tcgtgcgact gtattagata
      421 gtaatgcggt atggaaaaat agtgatggca agatgaactt gacttggcta atcaaatacc
      481 ggcgtagtga ttaggaaaca gggctcggat aacattattg cgcggttcat tgaacctact
      541 gatgacgccg gatatatagt cgtaaaccgt ttcgaaccag tacttatatc accaggagag
      601 tccatatatg accaccgttt acagtaaaaa cggtatctgt tttctgatcc ctccagcgtc
      661 aaactaccgt tgtaatggtg aggtctggtg ctattgtaat aattcagaat ataatctctg
      721 atttatttcc gaacctcgcc cttgcctgcg taaccatccg tcgcccccat cctgttttca
      781 gactgcggaa aaaggcaagt ttttatcccc ccacagagat tcaatcatat atcgcgtgtt
      841 ttggaagtga cagttcttat tcctgagaat acagcatgtg caacacactc ggcatccatc
      901 gataccactt ttatctctaa taggcaggat aaaaaacaag actgtgaatt aaagtaatcg
      961 gcaaatgaat gagttagaag ata
//
LOCUS       DAPGUL010000320          975 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.326, whole genome shotgun sequence.
ACCESSION   DAPGUL010000320 DAPGUL010000000
VERSION     DAPGUL010000320.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..975
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.326"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..538)
                     /locus_tag="RHX21_004930"
     CDS             complement(<1..538)
                     /locus_tag="RHX21_004930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016231857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB3 family type IV secretion system protein"
                     /protein_id="HDV1989957.1"
                     /translation="MSTLYKAMTRPAMYVGVPVVPLTVVAGALFLAGVYISKLIWLAI
                     PVAVFVLRMITKQDDHIFNLYFLKLKMLGNSVCNRFFGARAFLSGQYEAVEIDEFVNA
                     MKLNERITTGKYIPYSSHVDKNIVKTKNGDYVATWQLMGINFESISAEMLETIDSQVA
                     TLVRSFSGLPVSFYNHSCR"
     gene            complement(557..829)
                     /locus_tag="RHX21_004931"
     CDS             complement(557..829)
                     /locus_tag="RHX21_004931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001328551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="HDV1989958.1"
                     /translation="MQRKNKVVMAVAGATVASPAFADGFSKAETLLEKVKTGLSGLSL
                     VTVTIACLWVGYKVLFGGSTIRECSPIIIGAIVIASAAEVASMMVN"
BASE COUNT          296 a          227 c          194 g          258 t
ORIGIN      
        1 ccctgcatga atggttataa aatgaaacgg gcagtccgga aaatgaacga acaagagtgg
       61 caacctgtga gtcaatagtt tctaacatct ccgcagagat tgactcaaag ttaatcccca
      121 tcagttgcca tgtcgctaca taatcaccgt tttttgtttt gacgatgttt ttatcaacgt
      181 ggcttgaata tgggatatat ttaccagtag tgattcgctc attcagtttc atggcattaa
      241 caaactcatc aatttcaaca gcttcatatt gtccggagag gaacgctcgt gcgccaaaaa
      301 aacgattaca cactgagttt ccgagcattt tcagcttaag aaagtaaagg ttaaaaatgt
      361 ggtcgtcctg tttagttatc attctgagaa caaaaaccgc gacaggaata gccagccaga
      421 tcagcttgct gatataaacc cccgccagaa ataacgcccc tgcaaccaca gtaagaggga
      481 cgacaggaac acccacatac atagcagggc gtgtcatcgc tttataaagt gtagacatac
      541 tatcgtcccc gctttattag ttaaccatca ttgatgcaac ttcagccgca ctggcgataa
      601 caattgcccc gatgatgata ggtgagcatt cacgaatcgt gcttccacca aacagaacct
      661 tgtagccgac ccacagacag gcaatagtca ccgtgaccag tgaaagacca ctaagccctg
      721 ttttaacctt ttccagcagc gtttccgctt ttgaaaatcc atccgcaaag gccggtgatg
      781 caactgttgc cccggcgact gccataacta ccttattttt acgctgcatt acagcagtga
      841 cagatgaact gatacgatta catactgatt tcttaaatga cattttataa gtcctgttaa
      901 ttaataactt ttgttggatg tgagttatca acaaaagcag atttcagaat ggtttcgggc
      961 cagataactg acgca
//
LOCUS       DAPGUL010000321          972 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.327, whole genome shotgun sequence.
ACCESSION   DAPGUL010000321 DAPGUL010000000
VERSION     DAPGUL010000321.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..972
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.327"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..711)
                     /gene="tssI"
                     /locus_tag="RHX21_004932"
     CDS             complement(<1..711)
                     /gene="tssI"
                     /locus_tag="RHX21_004932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HDV1989959.1"
                     /translation="MSTGLRFTLEVDGLPPDAFAVVSFHLNQSLSSLFSLDLSLVSQQ
                     FLSLEFAQVLDKMAYLTIWQGDEVQRRVKGVVTWFELGENDKNQMLYSMKVHPPLWRA
                     GLRQNFRIFQNEDIKSILGTMLQENGVTEWSPLFSEPHPSREFCVQYGETDYDFLCRM
                     AAEEGIFFYEEHAYKSTDQSLVLCDTVRHLPESFEIPWNPNTRTEVSTLCISQFRYSA
                     QIRPSSVVTKDYTFKRPGW"
BASE COUNT          257 a          238 c          255 g          222 t
ORIGIN      
        1 ccagccgggt cgtttaaagg tgtagtcctt ggtcaccacg gaagaagggc ggatttgtgc
       61 gctgtagcgg aactggctga tgcagagggt gctcacctcg gtacgggtgt tcgggttcca
      121 tgggatttca aaagattcgg gcagatggcg gactgtgtcg cacagcacca ggctctggtc
      181 ggtacttttg taagcatgct cctcataaaa gaagatgcct tcctccgccg ccatccggca
      241 caggaaatcg taatcagtct caccgtactg gacacaaaac tcacgggaag gatgcggctc
      301 gctgaacagc ggactccatt cggtcacccc gttttcctgc aacatcgtgc cgaggatgct
      361 tttgatgtcc tcgttctgga agatacggaa gttctggcgc agaccggcac gccacagcgg
      421 cgggtgcacc ttcatgctgt acagcatctg gtttttgtcg ttctccccga gttcaaacca
      481 ggtcaccacg cctttcaccc ggcgctgtac ttcatcgccc tgccatatcg tcaggtaggc
      541 cattttgtcc agcacctgcg caaattcaag ggagagaaac tgctggctga ccagggagag
      601 atcgagggaa aagagcgaag agagtgactg gttcagatga aaggaaacca ccgcaaaagc
      661 atccggcggc aggccgtcca cttccagtgt gaaacgtaat ccggttgaca tagcaacctc
      721 cagtaaaatg aataatgatc cgtaccgtac aactgcggat aatgtgataa gcgggacgac
      781 ttcagacgtt attagggaag gaacagaaaa tgctatggtt atgtgagaat tttgtttaaa
      841 tattacttta cagaaacggg tgtctgttca gtcaaaaaaa taatcacaag ctcaacctct
      901 tgtttcttgg cgttattcag gacaggtacg catatcacaa cgagtaacaa aaacgcaaag
      961 ttaaaccaat at
//
LOCUS       DAPGUL010000322          968 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.328, whole genome shotgun sequence.
ACCESSION   DAPGUL010000322 DAPGUL010000000
VERSION     DAPGUL010000322.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 968)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 968)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..968
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.328"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            240..>968
                     /locus_tag="RHX21_004933"
     CDS             240..>968
                     /locus_tag="RHX21_004933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989960.1"
                     /translation="MSIDFTPGIINTYHGDIYNCTTNTDNVKTPDTSKWPCDNWEEQQ
                     PINSTFSGEGYNPEQFDLAQQQLQQINACHTNTTYTNADYSKVVVQLVSLINNIETIS
                     STPLTQQTQSILNQIHNIRYEKKNKSAECRIIVVANPKPDKAIITKISVEEGIPITFS
                     VQTMFSDTNFIAEQRADLPTNIKDIQSLYQKMTKLYIEHSENKNRMKVFAGTNFIDFN
                     MTGQNLSGFVLTLSRFYFEDLLNIN"
BASE COUNT          371 a          176 c          147 g          274 t
ORIGIN      
        1 caaaataact ttttaaaatg agcgcttttt gatagttgtt aacgttttcc tttacgatac
       61 tatcactgcc tttttttata cacaaatatt accgggtgga aatgaaaggg aatttaaagg
      121 taattatatc aggaagatat aacgcattat atttattgtg tgtagaagaa aatccattcc
      181 tgttctaatt atccaattta aaaaccttag cataaaacag atgatgaata aggaatgtta
      241 tgtcaattga ctttacccca ggtataataa atacatatca cggcgatatt tataactgca
      301 caacaaatac cgataatgtt aaaacgccag acacatcgaa gtggccttgt gataattggg
      361 aagaacaaca acccattaat tccacattct ctggagaagg atacaaccct gaacaatttg
      421 atttagcgca acaacaactc caacaaatta atgcatgcca cacgaacacc acatatacaa
      481 atgcagacta ctcaaaagtt gtggttcaac ttgtaagtct tattaataac attgaaacga
      541 taagttcgac accacttacg caacagacac aatcaatact taatcagatt cataacatta
      601 gatatgaaaa aaaaaacaaa agtgctgaat gtcgaatcat tgttgtcgct aatcctaaac
      661 ccgacaaggc aatcataact aaaattagcg tagaagaggg aatacccata acattcagtg
      721 tccaaaccat gttttcagat actaatttta ttgctgaaca acgagctgac ttaccaacta
      781 atataaaaga tattcaaagc ctgtatcaaa aaatgacgaa gttatatatt gagcacagtg
      841 aaaataaaaa caggatgaaa gtctttgccg gaaccaactt tattgatttc aatatgacag
      901 gacagaacct gtccgggttc gttctaacct tgtcaaggtt ttatttcgaa gatctactta
      961 atataaat
//
LOCUS       DAPGUL010000323          948 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.329, whole genome shotgun sequence.
ACCESSION   DAPGUL010000323 DAPGUL010000000
VERSION     DAPGUL010000323.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 948)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 948)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..948
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.329"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            37..822
                     /locus_tag="RHX21_004934"
     CDS             37..822
                     /locus_tag="RHX21_004934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDV1989961.1"
                     /translation="MNSKKLCCICVLFSLLAGCASESSIDEKKKKAQVTQSNINKNTP
                     QQLTDKDLFGNETTLAVSEEDIQAALDGDEFRVPLNSPVILVQSGNRAPETIMQEEMR
                     KYYTVSTFSGIPDRQKPLTCNKNKDKNENEDVASAENMNWMQALRFVAAKGHQKAIIV
                     YQDTLQTGKYDSALKSTVWSDYKNEKLTDAISLRYLVRFTLVDVATGEWATWSPVNYE
                     YKVLPPLPDKNEASTTDMTEQQIMQLKQKTYKAMVKDLVNRYQ"
BASE COUNT          313 a          189 c          206 g          240 t
ORIGIN      
        1 ttaccatgat tatgacaggc gagggagtgt ccaattatga attcaaaaaa gctttgttgc
       61 atatgtgtgt tattctcgct gcttgcagga tgtgcctctg aatcttctat tgatgaaaag
      121 aagaaaaaag ctcaagtcac acaaagtaat attaataaaa acactcccca gcaactgaca
      181 gacaaagatt tattcggtaa tgaaaccact ctggccgtat ccgaagagga tattcaagct
      241 gcgcttgatg gagatgagtt ccgcgttccc cttaattctc ctgtaatact tgttcaatcc
      301 ggcaaccgcg caccggaaac cattatgcag gaggagatgc gaaaatatta tactgtttcc
      361 acattctctg gtatcccgga caggcaaaag cctctgactt gtaacaaaaa caaagataaa
      421 aatgagaacg aggatgttgc cagtgctgag aatatgaact ggatgcaggc actgcgtttt
      481 gtggctgcaa aaggacatca gaaagcgatt attgtttacc aggatacatt gcagacagga
      541 aaatatgact ctgcgctgaa atcaacagta tggtccgact ataaaaatga aaaactcacc
      601 gacgctatct ccctgcgcta cctggtacgt ttcacgctgg tggatgtggc aacaggtgag
      661 tgggctacct ggtcgccggt gaattatgaa tataaagtgc ttccaccatt gcccgacaag
      721 aatgaagcca gtacgactga tatgacagag cagcaaatca tgcaacttaa gcaaaagacc
      781 tataaagcga tggtaaaaga tttggttaac cgctatcaat aataaattat atctgccgcc
      841 aggaatttct ggcggcaata atacaaaatt ctttgcataa gaaatttttc ttgacaaaga
      901 cagtgcaaga aaggacatgg aatccggagt taaaaactgt ttgtttta
//
LOCUS       DAPGUL010000324          946 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.330, whole genome shotgun sequence.
ACCESSION   DAPGUL010000324 DAPGUL010000000
VERSION     DAPGUL010000324.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 946)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 946)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..946
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.330"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            1..946
                     /locus_tag="RHX21_004935"
                     /pseudo
     CDS             1..946
                     /locus_tag="RHX21_004935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477168.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS3-like element IS3 family transposase"
BASE COUNT          225 a          242 c          281 g          198 t
ORIGIN      
        1 tcagcagacg tcttctgaac gtgaactgga gatgtctacc gagattgcac gtctcaaacg
       61 ccagctggca gaacgggatg aagagctggc tatcctccaa aaggccgcga catacttcgc
      121 gaagcgcctg aaatgaagta tgtctttatt gaaaaacatc aggctgagtt cagcatcaaa
      181 gcaatgtgcc gcgtgctccg ggtggcccgc agcggctggt atacgtggtg tcagcggcgg
      241 acaaggataa gcacgcgtca gcagttccgc caacactgcg acagcgttgt cctcgcggct
      301 tttacccggt caaaacagcg ttacggtgcc ccacgcctga cggatgaact gcgtgctcag
      361 ggttacccct ttaacgtaaa aaccgtggcg gcaagcctgc gccgtcaggg actgagggca
      421 aaggcctccc ggaagttcag cccggtcagc taccgcgcac acggcctgcc tgtgtcagaa
      481 aatctgttgg agcaggattt ttacgccagt ggcccgaacc agaagtgggc aggagacatc
      541 acgtacttac gtacagatga aggctggctg tatctggcag tggtcattga cctgtggtca
      601 cgtgccgtta ttggctggtc aatgtcgcca cgcatgacgg cgcaactggc ctgcgatgcc
      661 ctgcagatgg cgctgtggcg gcgtaagagg ccccggaacg ttatcgttca cacggaccgt
      721 ggaggccagt actgttcagc agattatcag gcgcaactga agcggcataa tctgcgtgga
      781 agtatgagcg caaaaggttg ctgctacgat aatgcctgcg tggaaagctt ctttcattcg
      841 ctgaaagtgg aatgtatcca tggagaacac tttatcagcc gggaaataat gcgggcaacg
      901 gtgtttaatt atatcgaatg tgattacaat cggtggcggc ggcaca
//
LOCUS       DAPGUL010000325          900 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.331, whole genome shotgun sequence.
ACCESSION   DAPGUL010000325 DAPGUL010000000
VERSION     DAPGUL010000325.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..900
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.331"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>900
                     /gene="gltS"
                     /locus_tag="RHX21_004936"
     CDS             <1..>900
                     /gene="gltS"
                     /locus_tag="RHX21_004936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HDV1989962.1"
                     /translation="VKFTPFLQKNHIPEAVVGGFIVAIVLLIIDKTSGYSFTFDASLQ
                     SLLMLTFFSSIGLSSDFSRLIKGGKPLVLLTIAVTILIAIQNTVGMSMAVMMNESPFI
                     GLIAGSITLTGGHGNAGAWGPILADKYGVTGAVELAMACATLGLVLGGLVGGPVARHL
                     LKKVSIPKTTEQERDTIVEAFEQPSVKRKINANNVIETISMLIICIVVGGYISALFKD
                     TFLQLPTFVWCLFVGIIIRNTLTHVFKHEVFEPTVDVLGSVALSLFLAMALMSLKFGQ
                     LASMAGPVLIIIAVQTVVMVLFA"
BASE COUNT          235 a          167 c          190 g          308 t
ORIGIN      
        1 tcgtaaaatt taccccgttc ctacaaaaaa accacatacc agaagccgtc gttggtggct
       61 ttattgttgc aattgttctg ttaattattg ataaaacatc aggttattcg tttacttttg
      121 atgcttcatt gcaaagttta ttaatgctca cattcttttc ctctatcggg ctaagttctg
      181 acttttctcg actgattaaa ggaggaaagc cgttagttct attaactatt gcagtaacga
      241 tcctaatcgc cattcaaaat actgtcggca tgagtatggc tgtcatgatg aatgaaagtc
      301 catttattgg cttaattgca ggttcaatta ctctaacagg tggtcatggt aatgccggag
      361 catggggccc tattctcgct gataaatatg gtgtaacagg cgccgttgaa ttagcgatgg
      421 cttgtgcaac acttggatta gtgttgggtg gtttagttgg cggccctgtt gcccgtcatc
      481 ttttgaaaaa ggtctctatt cctaaaacaa ccgagcaaga gcgcgacact atcgttgaag
      541 cttttgagca accaagcgtc aaaagaaaaa tcaatgcaaa taacgttatt gaaaccattt
      601 caatgctgat tatctgtatt gttgttggtg gctatatcag tgcattgttt aaagatactt
      661 ttctgcaact gcctactttt gtctggtgtt tatttgtcgg tattattatc cgtaatacac
      721 tgactcatgt atttaaacac gaagtgtttg agccgaccgt cgatgtatta ggtagcgttg
      781 ctttatcgct tttcttggca atggcgttaa tgtcattaaa atttggtcaa ttggcaagca
      841 tggcagggcc agtattaatt atcattgctg tacaaactgt tgtcatggtg ctatttgcct
//
LOCUS       DAPGUL010000326          895 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.332, whole genome shotgun sequence.
ACCESSION   DAPGUL010000326 DAPGUL010000000
VERSION     DAPGUL010000326.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..895
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.332"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     repeat_region   69..768
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=69..97
                     /rpt_unit_seq="gtgttccccgcgccagcggggataaaccg"
BASE COUNT          222 a          250 c          238 g          185 t
ORIGIN      
        1 gatactataa agttggtaga ttgtgactgg cttaaaaaat cattaattaa taataggtta
       61 tgtttagagt gttccccgcg ccagcgggga taaaccggca ttgacgcttt aaacgacgac
      121 ggacgccacg tgttccccgc gccagcgggg ataaaccgaa aacagccttt agattagtac
      181 ctgacgaccg gtgttccccg cgccagcggg gataaaccgt aaacgcacct ggcgcgccac
      241 tttatcaaca agtgttcccc gcgccagcgg ggataaaccg cggcttgttt aattgcgtgg
      301 aacgtctcaa ttgtgttccc cgcgccagcg gggataaacc gacggcgtgg attgagggac
      361 gggtatttgg tccgtgttcc ccgcgccagc ggggataaac ctagatcgcg ccacgaggaa
      421 acgaatatga acgggtgttc cccgcgccag cggggataaa ccgtgccgcc aggccagcga
      481 cacatcagac aactggtgtt ccccgcgcca gcggggataa accggtctgt gatggcctgc
      541 tcgtgagtcc gcggcggtgt tccccgcgcc agcggggata aaccgttttg atttcattaa
      601 cggcgctccc catatttgtg ttccccgcgc cagcggggat aaaccgtatt acgcgccagc
      661 aatgctgaca gcggcaaagt gttccccgcg ccagcgggga taaaccgcgc gagagccagc
      721 aaaacgccag ggcacaaaag agttccccgc gccagcgggg ataaaccacc atataacccg
      781 ttatctcttt ctcaagtttt tatattagca gtacttgtaa taagcaacat atccacgtaa
      841 cccctcatgt tcaaaatagt tctccatgcc agagaagttc acaattatcg ataca
//
LOCUS       DAPGUL010000327          864 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.333, whole genome shotgun sequence.
ACCESSION   DAPGUL010000327 DAPGUL010000000
VERSION     DAPGUL010000327.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 864)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 864)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..864
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.333"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            9..365
                     /locus_tag="RHX21_004937"
     CDS             9..365
                     /locus_tag="RHX21_004937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001387493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDV1989963.1"
                     /translation="MISQMSFSGAILWINIFSSVLLVPVYEEIVFRGCLFNSFKFWFN
                     DNIYTSAIVTSVIFSALHLQYTDFRTFLMLFLVSLVLISAKIKSNGLLMPILLHMSMN
                     AVIAGIQYLASISYTH"
     gene            complement(540..818)
                     /gene="mcmA"
                     /locus_tag="RHX21_004938"
     CDS             complement(540..818)
                     /gene="mcmA"
                     /locus_tag="RHX21_004938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001466656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin McmA"
                     /protein_id="HDV1989964.1"
                     /translation="MRKLSENEIKQISGGDGDDGQAELIAIGSLAGTFISPGFGSIAG
                     AYIGDKVHSWATTATVSPSMSPSGIGLSSQFGSGRGTSSASSSAGSGS"
BASE COUNT          253 a          176 c          147 g          288 t
ORIGIN      
        1 aagaatggat gatctcgcaa atgtcttttt ccggggccat tttatggatt aatatatttt
       61 cttctgtgct tcttgttcct gtatatgaag agattgtatt tcgagggtgt ctttttaact
      121 cttttaaatt ctggtttaat gacaatattt acacctctgc tattgtaaca tcagtcatat
      181 tttctgcatt acatctacaa tatactgact ttcgtacatt tttgatgctc tttctggtat
      241 cgttagttct tattagtgca aaaataaagt cgaatggcct gttaatgccc atattacttc
      301 acatgtcgat gaatgcagtc atagcaggaa tacaatatct ggcttctatc agttatactc
      361 attaacagag tattttctgt tacaatctca tatgataaaa attaaacgga ctggcattgt
      421 tactatgcgg tatgcataaa ataataaacg ttcggaggag cctaacttaa agcgttacat
      481 aggcaccatt atcatataat gaagcacctg taacatgtgc ttcattaaca atataaggtt
      541 taacttccac tccccgcaga cgaagaggca cttgatgtac ctctgccgga tccaaactgg
      601 gatgataatc ctatacctga gggagacatg gagggactaa ccgtcgcagt cgttgcccat
      661 gaatgtactt tatcacctat ataagcccct gcaatagaac caaatcccgg gctaataaac
      721 gtacctgcaa gtgaaccaat agcaattaat tctgcctgcc cgtcatcccc gtcacctcca
      781 gatatttgtt ttatttcatt ttcagatagt tttctcattt caacaccttc gctataagat
      841 ttgtgaagaa gtaaaaattc acgt
//
LOCUS       DAPGUL010000328          844 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.334, whole genome shotgun sequence.
ACCESSION   DAPGUL010000328 DAPGUL010000000
VERSION     DAPGUL010000328.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..844
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.334"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>844
                     /locus_tag="RHX21_004939"
     CDS             <1..>844
                     /locus_tag="RHX21_004939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS element protein"
                     /protein_id="HDV1989965.1"
                     /translation="RYGWTPRGELAAVYDRSNTQVRSFTYDDKYRGRMVAHRHTGRPE
                     IRYRYDSDGRVTEQLNPAGLSYTYQYEKDRITITDSLDRREVLHTQGEAGLKRVVKKE
                     HADGSVTQSQFDAVGRLRAQTDAAGRTTEYSPDVVTGLITRITTPDGRASAFYYNHHS
                     QLTSATGPDGLEMRRKYDEYGRLIQETAPDGDITRYRYDNPHSDLPCATDDATGSRKT
                     MTWSRYGQLLTFTDCSGYVTRYDHDRFGQVTAVHREEGLSQYHAYDSRGQLTAVKDTQ
                     GHETR"
BASE COUNT          209 a          246 c          259 g          130 t
ORIGIN      
        1 cgctatggct ggacgccgcg cggcgaactg gcggcagtgt atgaccgcag caatacacag
       61 gtgcgcagct ttacttacga tgataaatac cggggccgga tggtggcgca ccgtcacacg
      121 ggccgaccgg aaatccgtta ccgttacgac agcgacgggc gggtgacaga acagctaaac
      181 ccggcaggct taagctacac gtatcagtat gagaaagacc gcatcaccat caccgacagc
      241 ctggaccgcc gtgaagtgct gcacacgcag ggcgaagccg ggctgaagcg ggtggtgaaa
      301 aaggaacacg cggacggcag cgtcacacag agtcagtttg acgccgtggg caggctcagg
      361 gcacagacgg atgccgcagg ccggacaaca gagtacagcc cggatgtggt gacgggcctc
      421 atcacgcgca taaccacgcc ggatggcagg gcatcggcgt tttactataa ccaccacagc
      481 cagttaacgt cagccaccgg gccagacggg ctggaaatgc gccgcaaata tgatgagtac
      541 ggacgtctga ttcaggaaac cgcccctgac ggcgatatca cccgctaccg ttatgataat
      601 ccacacagtg acctcccctg cgcaacggac gatgccaccg gcagccggaa aaccatgacg
      661 tggagccgtt acggtcagtt gctgaccttc actgactgtt ccggttatgt aacccgctat
      721 gaccatgacc gttttggtca ggtgacggcg gtgcaccgcg aggaaggcct gagccagtac
      781 cacgcatacg acagccgtgg acagttaact gcggtgaaag acacgcaggg ccatgaaacg
      841 cggt
//
LOCUS       DAPGUL010000329          829 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.335, whole genome shotgun sequence.
ACCESSION   DAPGUL010000329 DAPGUL010000000
VERSION     DAPGUL010000329.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..829
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.335"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            103..435
                     /locus_tag="RHX21_004940"
     CDS             103..435
                     /locus_tag="RHX21_004940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001380893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989966.1"
                     /translation="MKGKNIALEKLASFPGSADIYHAIHLSFDIWVTCPLTSPDDIKN
                     FRNSFNKAKAQRKYKKMQEDKVNVQFFLDAETRAQLKELSRVRRLSTGEMLHDLIVEE
                     YKRYRHSR"
     gene            520..>829
                     /locus_tag="RHX21_004941"
     CDS             520..>829
                     /locus_tag="RHX21_004941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HDV1989967.1"
                     /translation="MNPSDAIEAIEKPLSSLPYSLSRHILEHLRKLTSHEPVIGIMGK
                     SGAGKSSLCNALFQGEVTPVSDVHAGTREVRRFRLSGHGHSMIITDLPGVGESRDRDA
                     E"
BASE COUNT          230 a          202 c          197 g          200 t
ORIGIN      
        1 atccagacca aagacagatg gatacgggca tttaaatcaa agagtccttt cagttacctc
       61 ctcccggaga acgaacatga atgcatatgg acatggaatt atttgaaggg aaaaaatatt
      121 gcactggaaa aactggccag ttttcctggt tctgctgata tttaccacgc aattcacctt
      181 tcatttgaca tatgggttac ctgtccactc acctcacctg acgatataaa aaatttcaga
      241 aacagtttca ataaggccaa ggcgcagcgc aagtacaaaa aaatgcagga agataaagtc
      301 aatgtacagt tttttcttga cgcagaaacc agggcgcagc tcaaagaatt atcgagggtc
      361 agaagactca gtaccggcga aatgctgcat gacctgattg ttgaagagta taaaaggtac
      421 cgacattcca gataatttca gacatatatt atctccgtga gtcccccgcc acctttccgg
      481 tgtgcggggg ttttgtcttt tttcaccggg aatacatgta tgaatccgtc tgatgccatt
      541 gaggcaattg aaaaaccgct ctcctccctg ccttactcac tttcccgtca catcctggaa
      601 catctgcgca aactcaccag tcacgaaccc gtgattggca ttatgggtaa aagcggggcc
      661 ggtaaatcct cactctgtaa tgcactgttt cagggggagg tcaccccggt cagtgatgtt
      721 cacgccggca cccgggaagt gcggcgcttc cgtctgagtg gccacggtca cagcatgatt
      781 atcactgacc tgcccggggt gggcgagagc cgggacaggg atgcagagt
//
LOCUS       DAPGUL010000330          826 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.336, whole genome shotgun sequence.
ACCESSION   DAPGUL010000330 DAPGUL010000000
VERSION     DAPGUL010000330.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 826)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 826)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..826
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.336"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            399..>826
                     /locus_tag="RHX21_004942"
     CDS             399..>826
                     /locus_tag="RHX21_004942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDV1989968.1"
                     /translation="MVLKNNKNSDCNDVQSLLAQGNQLLEGAYDITLIEMRLLYLALT
                     KIDSRKPQPANEYTLFAKEYRDTFSLDSKNCYEQLKSAASSLGSKPIVTYEWNEAKKR
                     IDAVKRFWFSSIRYGVGNSESDITLRFSDSVSQYLYELKS"
BASE COUNT          247 a          120 c          193 g          266 t
ORIGIN      
        1 ttatcagggg acagatttat ggttaaaagg ggacagattt atggtcaact agggacagat
       61 ttagtgtgga taactttttt atccacaggt tgtggataac tttttttaga ttcaactcgg
      121 attcgttatg gattctctat gaatctgaat tggattagtg acttagatca catttaggat
      181 gtttggctcg atgggttttt gatgatgcat tccctcctgg tttgctgtat tgactgcctc
      241 tgactgaggg tgaaaatgcg ccgttcagcc aggtttgacc cttcaaacag gggacagatt
      301 tatggtttat tagctatata gggacaaaaa aaaattgcgt ccctaatttg ggtgtgagaa
      361 acttcttttg atttttaact cacaggaagg ggagctgtat ggtcttaaag aataataaaa
      421 atagcgactg taatgatgtt caaagtttgt tggcacaggg aaatcaattg ctggaaggtg
      481 catacgatat aacgctaatt gaaatgcgtc ttctgtatct ggcattgact aagattgata
      541 gccgtaaacc acagcctgca aatgaatata cattgtttgc gaaggaatac agggacactt
      601 tttctttaga ttcgaaaaat tgttatgaac agttaaaatc tgctgcgagt tctttaggct
      661 caaagccaat tgttacgtat gaatggaacg aggcaaaaaa aaggatcgat gcagtcaaac
      721 gattctggtt ttcttcaata agatatggtg ttgggaatag tgaaagtgac ataactttgc
      781 gtttttcaga ttcggttagt caatatcttt atgaactgaa aagcga
//
LOCUS       DAPGUL010000331          815 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.337, whole genome shotgun sequence.
ACCESSION   DAPGUL010000331 DAPGUL010000000
VERSION     DAPGUL010000331.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..815
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.337"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..745
                     /locus_tag="RHX21_004943"
     CDS             <1..745
                     /locus_tag="RHX21_004943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001001722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="lipopolysaccharide 1,2-glucosyltransferase"
                     /protein_id="HDV1989969.1"
                     /translation="LIDPKYFADLPTSQFWSYATYFRVLSFEYLSESISTLLYLDADV
                     VCKGSLKPLTEIIFKDEFAAVIPDNDSTQAACAKRLNIPEMNGRYFNAGVIYVNLKKW
                     HEANLTPYLLKLLRGETKYGSLKYLDQDALNIAFNMNNIYLAKDFDTIYTLKNELYDR
                     SHRKYQQTITDKTVLIHYTGITKPWHSWAGYPSASYFNIAREQSPWKKYPLKEARTVA
                     EMQKQYKHLFAHGEYIKGITSLIKYKLKK"
BASE COUNT          266 a          150 c          151 g          248 t
ORIGIN      
        1 tttaattgac cccaaatact ttgctgatct gccgacgtca cagttttggt cgtacgcgac
       61 atacttcagg gtattgtctt ttgaatatct gagtgaaagt atttccacac tgctgtatct
      121 ggatgccgat gttgtttgta aaggaagcct gaaacctctc acagaaatta tatttaaaga
      181 tgagtttgct gcggtcattc ctgacaatga tagtactcag gcggcatgtg caaaacgcct
      241 caacattccc gaaatgaatg gacgttattt caatgcaggc gttatctatg tcaatcttaa
      301 aaaatggcat gaagcaaatt tgacaccgta tttactcaaa cttttacgag gggaaactaa
      361 atatggctct cttaaatatt tagatcagga tgcgttgaat atcgcattta atatgaataa
      421 tatctacctt gcgaaggatt ttgatactat ttataccctg aaaaacgaac tttatgatcg
      481 tagtcatcga aagtatcagc aaaccattac cgataaaaca gtgttgattc actatacagg
      541 gataactaaa ccatggcata gctgggctgg atatccgtct gcatcatact ttaatatcgc
      601 gcgtgaacaa tctccctgga agaaatatcc tcttaaagag gcgcggactg ttgcagaaat
      661 gcagaaacaa tataagcatc tgtttgccca tggtgagtat ataaaaggca taacttcatt
      721 aattaagtac aagcttaaga aataaattac tcttatgatt acaagtatac gttatcgcgg
      781 cttctcattt tattacaaag ataatgataa taaat
//
LOCUS       DAPGUL010000332          805 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.338, whole genome shotgun sequence.
ACCESSION   DAPGUL010000332 DAPGUL010000000
VERSION     DAPGUL010000332.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 805)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 805)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..805
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.338"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            8..>805
                     /locus_tag="RHX21_004944"
     CDS             8..>805
                     /locus_tag="RHX21_004944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV1989970.1"
                     /translation="MANLYDLKKFDLNLLVIFECIYQHLSISKAAESLYITPSAVSQS
                     LQRLRAQFNDPLFIRSGKGIAPTTTGLNLHHHLEKNLKGLEQTINIVNKSELKKNFII
                     YGPQLISCSNNSMLIRCLRQDASVEIECHDILMSAENAEELLVHRKADLVITQMPVIS
                     RSVICMPLHTIRNTLICSNKHPRITDNSTYEQIMAEEFTQLISKSAGVDDIQMEIDEK
                     FMNRKISFRGSSLLTIINSIAVTDLLGIVPYELYNSYRDFLNLKEIKL"
BASE COUNT          254 a          175 c          144 g          232 t
ORIGIN      
        1 gtagtgtatg gccaatctct acgacttgaa aaagttcgac ttaaaccttc ttgtcatatt
       61 tgagtgtatt taccagcatt taagcattag caaagctgct gaatcactat atatcacccc
      121 atcagccgtg agccagtcgt tacaacgctt acgtgcgcaa tttaatgacc ctttattcat
      181 tcgctcagga aaaggtatcg cgccgacgac aacagggttg aatctgcatc accatcttga
      241 gaaaaacctc aaaggccttg aacaaacaat taatatagtc aataagtccg aactaaagaa
      301 aaactttatt atttacggcc ctcagctcat ttcttgctct aataatagta tgctgatccg
      361 ctgcctacgg caagatgcct ctgtcgagat tgagtgccat gatatcctca tgtcagcaga
      421 gaatgctgaa gaactgttgg ttcaccgcaa agccgatctg gtgatcaccc aaatgccagt
      481 gatcagccgt tccgtcattt gcatgccatt gcatacaatt cgcaatactc taatttgtag
      541 taataagcat ccgcgaatta ctgacaatag cacttatgaa caaattatgg cagaagagtt
      601 cacccaatta atatccaaat cagcaggagt tgatgatatt caaatggaaa tagacgagaa
      661 gtttatgaat cgcaaaattt catttcgtgg ttcctctttg ctgacaatca ttaatagcat
      721 tgcagttaca gatttactgg gaatagtccc ctatgaactt tataattcct accgtgactt
      781 tcttaattta aaagagataa aacta
//
LOCUS       DAPGUL010000333          802 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.339, whole genome shotgun sequence.
ACCESSION   DAPGUL010000333 DAPGUL010000000
VERSION     DAPGUL010000333.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..802
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.339"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>802
                     /locus_tag="RHX21_004945"
     CDS             <1..>802
                     /locus_tag="RHX21_004945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308264.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HDV1989971.1"
                     /translation="RVTEQVNPEGLDYRFEYGERRVIITDSLNRREVLYTEGEGGLKR
                     VVKKEHADGSITRSEYDEAGRLKAQTDAAGRRTEYSLHMASGAVTAVTGPDGRTVRYG
                     YNSQRQVTSVTYPDGLRSSREYDEKGRLTAETSRSGETTRYSYDDPASELPTGIQDAT
                     GSTKQMAWSRYGQLLAFTDCSGYTTRYEYDRYGQQIAVHREEGISTYSSYNPRGQLVS
                     QKDAQGREIRYEYSAAGDLTATISPDGKRSTIAYDKRGRPVSVTEGGLT"
BASE COUNT          188 a          198 c          306 g          110 t
ORIGIN      
        1 cgggtgacgg agcaggtcaa cccggagggg ctggactacc gctttgagta cggagagcgc
       61 cgggtaatca tcacggacag cctgaaccgg cgggaggtgc tgtacacgga gggcgaaggc
      121 ggcctgaagc gggtggtgaa gaaggagcat gcggacggga gcatcacccg cagcgagtat
      181 gatgaggcgg ggaggctgaa ggcacagacg gatgcggcgg ggcggcggac ggagtacagc
      241 ctgcatatgg cgtcgggtgc ggtgacggcg gtgacggggc cggacggcag gacggtacgg
      301 tatggctata acagccagcg gcaggtgacg tcggtgacgt acccggacgg gcttcgcagc
      361 agccgggagt atgatgagaa gggaaggctg acggcggaga cctcgcgcag cggtgagaca
      421 acgcggtaca gctatgatga cccggcgagt gagctgccga cagggataca ggacgcgacg
      481 ggcagtacaa aacagatggc atggagccgt tacggtcaac tgctggcctt cacggactgc
      541 tcggggtaca cgacgcggta tgagtacgac cggtacggtc aacaaatcgc cgttcaccgg
      601 gaggaaggca tcagcactta cagcagttat aacccgcgtg ggcaactggt cagtcagaag
      661 gatgcgcagg ggcgtgaaat ccgttatgag tacagcgccg caggcgacct gacagcaacg
      721 atatcaccgg acggtaaacg cagcaccatc gcatatgata aacgcgggcg tccggtgagt
      781 gtgacggaag gcggtcttac gc
//
LOCUS       DAPGUL010000334          783 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.340, whole genome shotgun sequence.
ACCESSION   DAPGUL010000334 DAPGUL010000000
VERSION     DAPGUL010000334.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..783
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.340"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..693
                     /gene="ydeO"
                     /locus_tag="RHX21_004946"
     CDS             <1..693
                     /gene="ydeO"
                     /locus_tag="RHX21_004946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid stress response transcriptional regulator
                     YdeO"
                     /protein_id="HDV1989972.1"
                     /translation="AFSDGEILMVDNAVRTHFEPYERHFKEIGFNENTIKKYLQCTNI
                     QTVTVPVPAKFLRASNVPTGLLNEMIAYLNSEERNHHNFSELLLFSCLSIFAACKGFI
                     TLLTNGVLSVSGKVRNIVNMKLAHPWKLKDICDCLYISESLLKKKLKQEQTTFSQILL
                     DARMQHAKNLIRVEGSVNKIAEQCGYASTSYFIYTFRKHFGNSPKRVSKEYRCQSHTG
                     MNTGNTMSALAI"
BASE COUNT          237 a          158 c          162 g          226 t
ORIGIN      
        1 gccttctctg acggcgagat cctgatggta gataacgctg ttcgtacgca ttttgaacct
       61 tatgagcggc attttaaaga aatcggattt aatgaaaata ccattaaaaa atatctacaa
      121 tgcactaaca tccagacagt gacggtgcct gttcctgcga agtttttacg tgcttcaaat
      181 gtaccgactg gattgcttaa tgaaatgatt gcttatctca actcggaaga acgcaatcat
      241 cataattttt cagaactttt gcttttttct tgcctgtcta tatttgccgc atgcaaaggt
      301 ttcattacac tattaactaa cggtgtgcta tccgtttccg ggaaagtgag aaatattgtc
      361 aacatgaagc tggcgcaccc atggaagctg aaagatattt gtgactgcct gtacatcagt
      421 gaaagcctgt tgaagaaaaa actaaagcaa gagcaaacga cattctcaca gattctatta
      481 gatgccagaa tgcagcacgc aaaaaatttg atacgcgtag aaggttcagt caataaaatt
      541 gccgaacaat gtggttatgc cagtacatct tattttattt atacgttccg caaacatttc
      601 ggcaacagtc cgaagagagt ttctaaggag taccgttgtc aaagtcacac gggtatgaat
      661 acgggcaaca cgatgagtgc tttagctatt tgattatttg ctaacgagta gtcaaccacg
      721 cacgctacgt aagaattata tggggcagcc attccctgcc ccgcgttgtt tttaggcgat
      781 ata
//
LOCUS       DAPGUL010000335          780 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.341, whole genome shotgun sequence.
ACCESSION   DAPGUL010000335 DAPGUL010000000
VERSION     DAPGUL010000335.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..780
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.341"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            51..767
                     /locus_tag="RHX21_004947"
     CDS             51..767
                     /locus_tag="RHX21_004947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDV1989973.1"
                     /translation="MGRKWANIVAKKTAKDGATSKIYAKFGVEIYAAAKQGEPDPELN
                     TSLKFVIERAKQAQVPKHVIDKAIDKAKGGGDETFVQGRYEGFGPNGSMIIAETLTSN
                     VNRTIANVRTIFNKKGGNIGAAGSVSYMFDNTGVIVFKGTDPDHIFEILLEAEVDVRD
                     VTEEEGNIVIYTEPTDLHKGIAALKAAGITEFSTTELEMIAQSEVELSPEDLEIFEGL
                     VDALEDDDDVQKVYHNVANL"
BASE COUNT          258 a          134 c          169 g          219 t
ORIGIN      
        1 tgttaacgat ttaccagtaa tgtaaataaa ttttcgagga gatcattcca gtgggacgta
       61 aatgggccaa tattgttgct aaaaaaacgg ctaaagacgg tgcaacgtct aaaatttatg
      121 caaaattcgg tgtagaaatc tatgctgctg ctaaacaagg tgaacccgat ccagaattaa
      181 acacatcttt aaaattcgtt attgaacgtg caaagcaggc acaagttcca aagcacgtta
      241 ttgataaagc aattgataaa gccaaaggcg gcggagatga aacgttcgtg cagggacgtt
      301 atgaaggctt tggtcctaat ggctcaatga ttatcgccga gacattgact tcaaatgtta
      361 accgtacgat tgctaacgtt cgcacaattt tcaataaaaa aggcggcaat atcggagcgg
      421 caggttctgt cagctatatg tttgacaata cgggtgtgat tgtatttaaa gggacagacc
      481 ctgaccatat ttttgaaatt ttacttgaag ctgaagttga tgttcgtgat gtgactgaag
      541 aagaaggtaa cattgttatt tatactgaac ctactgacct tcataaagga atcgcggctc
      601 taaaagcagc tggaatcact gagttctcaa caacagaatt agaaatgatt gctcaatctg
      661 aagttgagct ttccccagaa gatttagaaa tctttgaagg gcttgttgat gcccttgaag
      721 atgacgacga tgtacaaaaa gtttatcata acgtcgcaaa tctctaatta tcttttaaag
//
LOCUS       DAPGUL010000336          772 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.342, whole genome shotgun sequence.
ACCESSION   DAPGUL010000336 DAPGUL010000000
VERSION     DAPGUL010000336.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 772)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 772)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..772
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.342"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            83..649
                     /gene="slp"
                     /locus_tag="RHX21_004948"
     CDS             83..649
                     /gene="slp"
                     /locus_tag="RHX21_004948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312404.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein Slp"
                     /protein_id="HDV1989974.1"
                     /translation="MNMTKGALILSLSFLLAACSSIPQNIKGNNQPDIQKSFVAVHNQ
                     PGLYVGQQARFGGKVINVINGKTDTLLEIAVLPLDSYAKPDIEANYQGRLLARQSGFL
                     DPVNYRNHFVTILGTIQGEQPGFINKVPYNFLEVNMQGIQVWHLREVVNTTYNLWDYG
                     YGAFWPEPGWGAPYYTNAVSQVTPELVK"
BASE COUNT          231 a          162 c          163 g          216 t
ORIGIN      
        1 caggcatatc acctcagaat cagatgaaaa ctataaagaa atatctatta tggttttaat
       61 atttgttgat aaggatagta acatgaacat gacaaaaggt gcactcatcc tcagcctttc
      121 atttttgctt gccgcatgta gttcaattcc gcaaaatatc aaaggcaata accaacctga
      181 tattcaaaaa agttttgttg ctgttcataa ccagccgggg ttatatgttg gtcaacaagc
      241 gcgctttggt gggaaggtta tcaacgttat caatggcaaa acggatacgt tgttagaaat
      301 cgctgtatta ccgttggata gctatgcgaa gcctgatatt gaagccaact atcagggccg
      361 actgctcgcc agacaaagcg gcttccttga tccagtgaac tatcgtaatc actttgttac
      421 catcctcggt accattcagg gtgaacaacc aggctttatc aataaagtcc cgtataactt
      481 cctggaagtg aatatgcagg gcatccaggt gtggcatttg agagaagtgg ttaataccac
      541 ctataacctg tgggattacg gctatggtgc attctggccg gaaccgggct ggggtgcgcc
      601 ttactacacc aatgcggtga gtcaggtaac acctgagctg gtcaaataac accaccgaaa
      661 gatgcagatg ctttctcagc atctgcatca tgtattacat aaaattaata tacagtaagc
      721 taactattat tataagccct gtcctgttaa ttacctttgg caaactgatt at
//
LOCUS       DAPGUL010000337          741 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.343, whole genome shotgun sequence.
ACCESSION   DAPGUL010000337 DAPGUL010000000
VERSION     DAPGUL010000337.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..741
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.343"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..734)
                     /locus_tag="RHX21_004949"
     CDS             complement(<1..734)
                     /locus_tag="RHX21_004949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion protein Rhs"
                     /protein_id="HDV1989975.1"
                     /translation="MDIVQGSAGVLIGAPTGVACSVCPNSPIEEQKGNPVNPLLGAKV
                     LPGETDLALPGPLPFILSRAYSSYRTRTPAPVGVFGPGWKAPFDIRLQVHERELILND
                     SGGRSIHFEPLFPGEVSYSRSESFWLARGGVAEQHSSQPLSALWQVLPEDVRLSPHVY
                     LATNSLQGPWWILSWPERVPGADEVLPPEPPAYRVLTGVVDGFGRTLAFHRAAEGDVA
                     GAVTGVTDGAGRRFHLVLTTQAQRAEV"
BASE COUNT          125 a          286 c          210 g          120 t
ORIGIN      
        1 acttccgccc gctgtgcctg tgtggtcagc accaggtgaa aacggcggcc cgcgccgtcc
       61 gtcacccccg tcaccgcgcc cgccacatca ccctccgccg cccggtgaaa ggccagcgtc
      121 cgcccgaagc cgtccaccac gcccgtcagc acccggtatg cgggcggctc cggcggcagc
      181 acctcgtccg cccccggcac ccgctccggc cagctgagta tccaccacgg cccctgaagg
      241 ctgtttgtcg ccaggtacac atgcggactc aggcgaacat cttccggcag cacctgccag
      301 agtgcgctta gcggctgcga actgtgctgc tccgccaccc cgccccgcgc cagccagaac
      361 gactcgctgc ggctgtagct tacctcgccg ggaaacagcg gctcaaagtg aatgctcctg
      421 ccgccgctgt cgttgagtat cagttcccgc tcatgaacct gtaagcggat atcgaagggt
      481 gctttccagc cgggaccgaa cacccccacc ggcgcgggcg tcctggtccg gtaactgctg
      541 taggcgcggg aaagaataaa cggcaacggg ccgggcagcg caaggtccgt ctcgcccggc
      601 agcacctttg ctcccagcag cgggttcacc gggttaccct tctgctcctc tatcgggctg
      661 ttgggacata ccgaacaggc cactcccgtc ggcgcgccta tcagcacccc tgctgaaccc
      721 tgcacaatat ccagtccctt g
//
LOCUS       DAPGUL010000338          738 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.344, whole genome shotgun sequence.
ACCESSION   DAPGUL010000338 DAPGUL010000000
VERSION     DAPGUL010000338.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..738
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.344"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>738
                     /locus_tag="RHX21_004950"
     CDS             <1..>738
                     /locus_tag="RHX21_004950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989976.1"
                     /translation="SIGNDISSDLVRRKMNDLPESPIGNNLEALAPGIEKLKQTSIQM
                     VTLLNALQPGGKCIITGDFQKELAYLQNVILYNDSSLRLDFLGYNAQIIQRSDNTCEL
                     TINEPLKNQEISTGNINVNCPLKDIYNEIRRLNVIFSCGTGDIVDLSSLDLRNVDLDY
                     YDFTDKHMANTILNPFKLDSTNFTNANMFQVNFVSSTQNVTISWGYLLKITPVLISIS
                     DMYSEEKIKFVESCLNELGDITEEQLK"
BASE COUNT          261 a          124 c          121 g          232 t
ORIGIN      
        1 catcaattgg taatgatatt agtagtgatt tagtccgtcg aaaaatgaat gaccttcctg
       61 aaagccccat aggaaataac ctcgaagcac tagcaccagg tatagaaaaa ctaaaacaga
      121 cctctattca aatggtcact ttacttaacg cgttacaacc aggtggaaaa tgcattatca
      181 ctggtgattt tcaaaaagaa ttagcgtact tacaaaatgt aattctttat aatgactcgt
      241 ctcttcgtct ggatttttta ggttataacg cccaaattat tcaacgttcg gacaatacct
      301 gcgaacttac cattaatgaa ccgttaaaaa accaggaaat atctacaggc aatatcaatg
      361 ttaattgccc attaaaagat atttacaatg aaatcaggag gttgaacgta atctttagtt
      421 gtgggactgg agatatagtt gatctatcct ctctggactt acgtaatgtc gatttagatt
      481 attatgattt cacagataaa catatggcta atactatttt aaatcctttt aaattggatt
      541 caacaaattt tactaatgcc aacatgtttc aggttaattt tgttagttca acacaaaacg
      601 tcacaatctc ctggggttat ttactaaaaa taacgcctgt tttaataagc attagcgata
      661 tgtattctga agaaaaaatc aagtttgtcg aaagttgttt aaatgagctt ggagacatta
      721 ccgaagaaca attaaaga
//
LOCUS       DAPGUL010000339          723 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.345, whole genome shotgun sequence.
ACCESSION   DAPGUL010000339 DAPGUL010000000
VERSION     DAPGUL010000339.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 723)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 723)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..723
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.345"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            175..250
                     /locus_tag="RHX21_004951"
     tRNA            175..250
                     /locus_tag="RHX21_004951"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:208..210,aa:Ile,seq:cat)
BASE COUNT          208 a          138 c          168 g          209 t
ORIGIN      
        1 taacatttgc ttgttgactg cgagtatcga ctttgcgaat ggaagcggtg tcgggtttta
       61 tgtcgcgtgt aatgacgagc aaggatgaat gagaacgcat aaaaatctgt tatttacatc
      121 atatgatcat catgtttatt gcgtggttta taagtattgt tattgcacac tcaaggccct
      181 ttagctcagt ggttagagca ggcgactcat aatcgcttgg tcgctggttc aagtccagca
      241 agggccacca aatcattatt tacgtatcag gaagagttaa gggtacaagg ggtactcgat
      301 ggcggtctat atttcatgac taacgccatt tcaaggaaga agtgcggtgg gtggtttcga
      361 atgagggctg gtgttttggt acgtggcacg ccactgcaat atatttatcc atcagtactc
      421 attcaaaagt acctggaaaa aatgcctgct atgccaagcg ggcaaattgc ttacatgtgg
      481 aattaagtaa ttaacgataa agccagagta ttatcattta ttatacccct taatttaatc
      541 aggttaatta ctcaaatcac tgaactattc tctgttcgct cactgatgat gagtgagtac
      601 cacaaccaat gtatgtagaa caatgccgta gagtaaggat gaaatgtctc tgccacgcct
      661 taaacatcta ctactgacca gaacacccgc cgcaggcaga tgagttttgt gagcgttaca
      721 gga
//
LOCUS       DAPGUL010000340          720 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.346, whole genome shotgun sequence.
ACCESSION   DAPGUL010000340 DAPGUL010000000
VERSION     DAPGUL010000340.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..720
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.346"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            1..521
                     /locus_tag="RHX21_004952"
                     /pseudo
     CDS             1..521
                     /locus_tag="RHX21_004952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311739.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(540..720)
                     /locus_tag="RHX21_004953"
                     /pseudo
     CDS             complement(540..720)
                     /locus_tag="RHX21_004953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019843029.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
BASE COUNT          244 a          117 c          140 g          219 t
ORIGIN      
        1 atctgaagaa agctatagcg gagtgtaaca aatctacagc ctaaatattt attttaggag
       61 aatttgcagg tggaatgatg gggtccgaac tcgtaaaatg ggttaaatcg cataagatag
      121 atgctcatat tattacattt gtagcaaaga tgccgtatat tgattcaata aaattgcttg
      181 aagcaggtgc gaaaggatgc gtatggaaaa ccagtcaccc ggcgaaacta aatcgtgcta
      241 ttgattcgat tagtaatggt tacacttatt ttgatagtgt acatatggat tgtgaaaaaa
      301 tatcttccag gtattcctct gataatcaac ttacaaatcg tgagtcagaa atattacaac
      361 tcatagctga tggtaaaaca aacaaagaaa tcgctaattt cttgcagtta agcagaaaaa
      421 aagtcgaaac tcatagactc aatatcatga agaaattaga tgttcacagt ggtatcgagt
      481 tgatcaaaac agctttacgt atgggtgttt gcactatata aaaaaaagag gctttaggct
      541 cattttgctg aagccttacg attgtctagt tcattaagcc tggtatatac aatatatatt
      601 ttggggcata ttgctgtctc tttttttggt tatccattgc aaaacccgca ttataagtcc
      661 ccaggcattg ccacgttact ccacaacgtg aaaaatggtt atataaaatc tcggttccta
//
LOCUS       DAPGUL010000341          712 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.347, whole genome shotgun sequence.
ACCESSION   DAPGUL010000341 DAPGUL010000000
VERSION     DAPGUL010000341.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 712)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 712)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..712
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.347"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..648
                     /gene="istB"
                     /locus_tag="RHX21_004954"
     CDS             <1..648
                     /gene="istB"
                     /locus_tag="RHX21_004954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001514323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element ISEc12 family helper ATPase
                     IstB"
                     /protein_id="HDV1989977.1"
                     /translation="GFEERLSLLTAEELTCRENRKAERLIKHARFRLNAELSKLDYRN
                     NRGLDRALIRSLSQGNWLTLKQNILLTGATGSGKTFLACALGHNACRQGYKVYYYRLK
                     ALMEQCYQGHADGRYSKLLTRLNNSDLLLLDDWGLEPLSSEQRSDLLEIVDLMYQRGS
                     IIVVSQLPVENWYKMIGDSTHADAILDRLVHGSIKIELKGESMRKIQSPLTEGDQ"
BASE COUNT          213 a          160 c          182 g          157 t
ORIGIN      
        1 ggcttcgaag aacgcctgtc attactgaca gcagaagaac taacctgccg tgaaaacagg
       61 aaggcagagc gtctgatcaa acatgcacgg ttcagactta atgctgagtt atcaaagctg
      121 gattatcgta acaatagagg gctggacagg gccctcatcc gttcactcag tcagggaaac
      181 tggttaaccc tgaaacaaaa tattttactg accggggcca ccggcagcgg taaaacgttc
      241 ctggcatgtg cacttggtca taatgcctgc cgacagggat acaaggtcta ctattatcgc
      301 cttaaagcgc tgatggaaca gtgctatcag gggcatgctg atggaagata cagcaaactt
      361 ttgaccaggc tgaataatag cgatctgctg cttctggatg actgggggct ggaacctctc
      421 tcatcagaac agcgtagcga cctgctggaa atagtggatc tgatgtacca acgaggctca
      481 atcatcgtag tgagccagtt gccggtggaa aactggtaca aaatgatcgg agactccaca
      541 catgcggatg ccatcctaga tcgactggtt catggcagta tcaagatcga acttaaagga
      601 gaatcaatgc ggaaaataca atctccgttg accgaaggag atcagtgaag gtaatttaaa
      661 aacggttctg tgaaagtgac acgaaccgat ctccatcgat gttactcacc ga
//
LOCUS       DAPGUL010000342          710 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.348, whole genome shotgun sequence.
ACCESSION   DAPGUL010000342 DAPGUL010000000
VERSION     DAPGUL010000342.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 710)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 710)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..710
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.348"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(1..710)
                     /locus_tag="RHX21_004955"
                     /pseudo
     CDS             complement(1..710)
                     /locus_tag="RHX21_004955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312389.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="DUF4049 domain-containing protein"
BASE COUNT          211 a          134 c          116 g          249 t
ORIGIN      
        1 tttagcccca taataccatt atcaaattgt tgattctgat ctaccccgac cccatgatgc
       61 ccatattttt gtctaatgta tttgctgggg tcttcacctt tgagtgtctc cccatatatg
      121 aagatacgtt tacgtgctgg tctgaaatca gtagtgttat caaaataatt agcatataca
      181 ggtgtgggtt tcaaagtatt gcttcggatt agatggaaca gaggatcatc catgtgttct
      241 ttatgttttt tattaaaaat attggctaat tcctcaggat cagtaggatt tttcatctga
      301 ttaaatggaa cctgcaaagc accgagacaa taacattttt ttcttcatct cttattattc
      361 cgtgatgact ggttaaaact ttcctttctg agtcataatt acaaacatcg agcgttttaa
      421 ttaagttata cgtatcaccg gaagagagtt tatgatttgc tagtcgtgca ctatagttac
      481 cattaaaatt gatttcatga tttccagcca gaacgacgac atttttattt atacgactat
      541 ctttattacc ctccatattt cgcatagaat ttagcaaagt aaggatatat ttatcaccaa
      601 aaatagtact gaatctatcg cctgtatgat ccccaaggaa gatacaaggg gtaatcgcat
      661 cgccttttaa aaaaacatgt tgatgcaact cattcaatat catgtctctc
//
LOCUS       DAPGUL010000343          708 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.349, whole genome shotgun sequence.
ACCESSION   DAPGUL010000343 DAPGUL010000000
VERSION     DAPGUL010000343.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 708)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 708)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..708
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.349"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..424
                     /locus_tag="RHX21_004956"
     CDS             <1..424
                     /locus_tag="RHX21_004956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Hcp family type VI secretion system effector"
                     /protein_id="HDV1989978.1"
                     /translation="CSTLDSVGNKAQPEHKDQIMVYALMHSISRSQNVNHHELIITKP
                     VDKSSPLLAKALSDNEKMAICEFILYRTSKAGIYQPYYKINLSKARISSIDFVTPHAV
                     LEKELEPQERIAFIYEDISWEHTLAGTNAMSKWQDRVQ"
     gene            468..>708
                     /locus_tag="RHX21_004957"
     CDS             468..>708
                     /locus_tag="RHX21_004957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989979.1"
                     /translation="MAGLRNNNNTQNAQWADYVGDILRGAQPINQLVPQHPYLNDVPL
                     IDELRHQNTHHVILLTLDVAKKILSPITSFDYIHFI"
BASE COUNT          242 a          142 c          132 g          192 t
ORIGIN      
        1 ttgctcaacg cttgattctg tcggaaacaa agcgcagcca gaacataaag atcagatcat
       61 ggtttatgcg ttaatgcatt ccatctcaag aagtcaaaat gtcaatcatc atgaattaat
      121 tatcaccaaa ccggttgata aatcctcacc attgctggca aaagcactta gtgacaatga
      181 aaaaatggca atatgtgaat ttatactcta ccgaaccagt aaagcgggta tttaccagcc
      241 ttattataaa ataaatctgt caaaagcccg aatatcaagt attgattttg tcacaccgca
      301 tgctgtcctg gaaaaagaac tggaaccaca ggagagaatt gcctttattt atgaagatat
      361 ttcctgggag catacgttag ccggtacgaa tgcaatgagt aaatggcagg atcgtgtaca
      421 gtaacttact gtaataacat aataaattac tattgcggag agataaaatg gctggtttaa
      481 ggaataacaa caacacacag aatgcacagt gggctgatta tgtgggtgac attcttcggg
      541 gggctcagcc gataaaccag ctagtacctc agcaccctta tcttaacgac gtcccactca
      601 ttgatgagtt aaggcatcag aacactcatc atgttattct cttgacactt gatgttgcaa
      661 aaaaaatact cagcccaata acatcatttg attacattca ttttatca
//
LOCUS       DAPGUL010000344          703 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.350, whole genome shotgun sequence.
ACCESSION   DAPGUL010000344 DAPGUL010000000
VERSION     DAPGUL010000344.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..703
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.350"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>703
                     /locus_tag="RHX21_004958"
     CDS             <1..>703
                     /locus_tag="RHX21_004958"
                     /inference="COORDINATES: protein motif:HMM:TIGR03696.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat-associated core domain-containing
                     protein"
                     /protein_id="HDV1989980.1"
                     /translation="RYGWTPRGELAVVYDRSNTQVRSFTYDDKYRGRMVAHRHTGRPE
                     IRYRYDSDGRVTEQLNPAGLSYTYQYEKDRITITDSLNRREVLHTAGEGGLKRVVKKE
                     HADGSVTQSQFDAVGRLRAQTDAAGRTTEYSPDVVTGLITRITTPDGRASAFYYNHHS
                     QLTSATGPDGLEIRREYDEWGNQLNEENPHQLQQLIRLPGQQYDEESGLYYNRHRYYD
                     PLRGRYITQDPIGLKG"
BASE COUNT          173 a          196 c          228 g          106 t
ORIGIN      
        1 cgctatggct ggacgccgcg cggcgaactg gcggtggtgt atgaccgcag caatacacag
       61 gtgcgcagct ttacttacga tgataaatac cggggccgga tggtggcgca ccgtcacacg
      121 ggccggccgg aaatccgtta ccgttacgac agcgacgggc gggtgacaga acagctaaac
      181 ccggcaggct taagctacac gtatcagtat gagaaagacc gcatcaccat caccgacagc
      241 ctgaaccgcc gtgaagtcct gcataccgca ggcgaaggcg ggctgaagcg ggtggtgaaa
      301 aaggaacacg cggacggcag cgtcacgcag agtcagtttg acgcggtggg caggctcagg
      361 gcacagacgg atgccgcagg caggacaaca gaatacagcc cggatgtggt gacgggcctc
      421 atcacgcgca tcaccacgcc ggatggcagg gcatcggcgt tttactataa ccaccacagc
      481 cagttaacgt cagccaccgg gcctgacggg ctggaaatac gccgggaata cgatgaatgg
      541 ggtaaccagc tgaatgaaga gaacccgcac cagctgcagc agctcatccg cctgccgggg
      601 cagcagtatg atgaggagtc cggcctgtat tataaccgcc accgctatta tgacccgctg
      661 cgggggaggt atatcactca ggatccgatt gggctgaagg ggg
//
LOCUS       DAPGUL010000345          696 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.351, whole genome shotgun sequence.
ACCESSION   DAPGUL010000345 DAPGUL010000000
VERSION     DAPGUL010000345.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.351"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..663
                     /locus_tag="RHX21_004959"
     CDS             <1..663
                     /locus_tag="RHX21_004959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005025120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HDV1989981.1"
                     /translation="TRSMIHRWTDDKLKYALLFATEKGYQAKDNNHAIQIFRNHIYGR
                     LSFIKMVRGKDYPGYLKLMSYMSHNDPLKTQEGLRAMKETENFDVFICHASEDKKDIA
                     IPIYDELTKLKISAFIDHVEIKWGDSLIEKINAALVKSKYVIAILSANSVNKEWPQKE
                     LRAVLASEISSGDVKLLTLLKKEDEEVVNLSLPLLSDKYYMVYDNNPEVVANNIKSLL
                     QR"
BASE COUNT          270 a          113 c          123 g          190 t
ORIGIN      
        1 acacgttcaa tgattcatag atggacagat gataagctaa agtatgcact tctctttgct
       61 acagaaaaag gatatcaggc aaaggataat aaccacgcaa ttcaaatttt ccgaaatcat
      121 atttatggaa ggcttagctt tataaaaatg gttagaggga aagactatcc aggatattta
      181 aaactgatgt catacatgag tcataacgat ccattaaaaa cccaagaagg attgcgagca
      241 atgaaagaaa cagaaaactt tgatgttttt atatgccatg caagcgaaga caaaaaagac
      301 attgcaattc caatatatga cgagttaact aaacttaaaa tttcagcctt catagatcat
      361 gttgagataa aatggggcga ctccttaatt gagaaaataa atgcagcact agttaaatca
      421 aaatatgtca tcgctatttt atctgctaat tcagtcaata aggaatggcc tcaaaaagaa
      481 ttaagggcag ttttagccag cgaaatatcg agtggcgacg taaaactttt gaccttatta
      541 aaaaaagaag acgaggaggt cgtaaaccta tcattacctt tacttagtga taagtattat
      601 atggtctatg ataataatcc tgaagtagtc gccaacaata ttaaatcact cttacaacga
      661 taattctctc acaaaagcaa atgtgcagat tgatgc
//
LOCUS       DAPGUL010000346          688 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.352, whole genome shotgun sequence.
ACCESSION   DAPGUL010000346 DAPGUL010000000
VERSION     DAPGUL010000346.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 688)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 688)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..688
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.352"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..348
                     /locus_tag="RHX21_004960"
     CDS             <1..348
                     /locus_tag="RHX21_004960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase"
                     /protein_id="HDV1989982.1"
                     /translation="FEPYPAALHGQFDSISMFYLLHCLPGNISTKSCVIRNAAQALTD
                     DGTLYGATILGDGVVHNSFGQKLMRIYNQKGIFSNTKDSEEGLTHILSEHFENVKTKV
                     QGTVVMFSASGKK"
BASE COUNT          203 a          161 c          118 g          206 t
ORIGIN      
        1 tttgaacctt atcccgcggc gttacatggt caatttgatt ccatttccat gttttacctt
       61 cttcactgcc tgcctggaaa tatatctaca aaaagctgtg taatacgcaa tgcggcgcag
      121 gccttaactg acgatggaac tctatacgga gccacaattc ttggcgatgg agttgtgcac
      181 aatagcttcg gtcaaaaact gatgcgcatt tacaatcaga aaggcatctt ttcaaacaca
      241 aaagattccg aagaaggctt aacacatata ctctcagagc atttcgagaa tgttaaaacc
      301 aaggttcaag gtactgtagt aatgttttcc gcttcaggga aaaaatagca tccaaccgca
      361 gcacgttctt gcataaggcg tgtctgcggt ttttcaacta ttcagataca tcactcccat
      421 cacattcatt cctccgcatc ataggcatat aggctatatc accttgatat ttttcttctt
      481 cagataaaaa ctgttatcta tgtatacttt taaacccaat ccgtgtagag tctctgcata
      541 agatagtttg cagttgccac ttcagcttgc gccataaacc gcctgatttt tgccgccacc
      601 tgttagcatt cctgtatacc tgaaacgaca atgtttatct acgaacttta agaacaccca
      661 ggataaaaat tgtcaactat atcatata
//
LOCUS       DAPGUL010000347          686 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.353, whole genome shotgun sequence.
ACCESSION   DAPGUL010000347 DAPGUL010000000
VERSION     DAPGUL010000347.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 686)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 686)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..686
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.353"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>686
                     /locus_tag="RHX21_004961"
     rRNA            <1..>686
                     /locus_tag="RHX21_004961"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          175 a          155 c          226 g          130 t
ORIGIN      
        1 ctgagaggat gaccagccac actggaactg agacacggtc cagactccta cgggaggcag
       61 cagtggggaa tattgcacaa tgggcgcaag cctgatgcag ccatgccgcg tgtatgaaga
      121 aggccttcgg gttgtaaagt actttcagcg gggaggaagg gagtaaagtt aatacctttg
      181 ctcattgacg ttacccgcag aagaagcacc ggctaactcc gtgccagcag ccgcggtaat
      241 acggagggtg caagcgttaa tcggaattac tgggcgtaaa gcgcacgcag gcggtttgtt
      301 aagtcagatg tgaaatcccc gggctcaacc tgggaactgc atctgatact ggcaagcttg
      361 agtctcgtag aggggggtag aattccaggt gtagcggtga aatgcgtaga gatctggagg
      421 aataccggtg gcgaaggcgg ccccctggac gaagactgac gctcaggtgc gaaagcgtgg
      481 ggagcaaaca ggattagata ccctggtagt ccacgccgta aacgatgtcg acttggaggt
      541 tgtgcccttg aggcgtggct tccggagcta acgcgttaag tcgaccgcct ggggagtacg
      601 gccgcaaggt taaaactcaa atgaattgac gggggcccgc acaagcggtg gagcatgtgg
      661 tttaattcga tgcaacgcga agaacc
//
LOCUS       DAPGUL010000348          683 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.354, whole genome shotgun sequence.
ACCESSION   DAPGUL010000348 DAPGUL010000000
VERSION     DAPGUL010000348.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..683
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.354"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..218
                     /locus_tag="RHX21_004962"
     CDS             <1..218
                     /locus_tag="RHX21_004962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="porin"
                     /protein_id="HDV1989983.1"
                     /translation="NKDGNKLDLYGKVTALRYFTDDKRDDGDKTYARLGFKGETQIND
                     QMIGFGHWEYDFKGYNDEANGSRGKNL"
     gene            242..>683
                     /locus_tag="RHX21_004963"
     CDS             242..>683
                     /locus_tag="RHX21_004963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HDV1989984.1"
                     /translation="MITDLILHNHPRMKTITLNDNHIAHLNAKNTTKLEYLNLSNNHL
                     LPTNDIDQLISSKHLWHVLVNGINNDPLAQMQYWTAVRNIIDDTNEVTIDLSGLNLTT
                     QPPGLQNFTSINLDNNQLTHFDATNYDRLVKLSLNSNTLDSINFP"
BASE COUNT          246 a          145 c          107 g          185 t
ORIGIN      
        1 ataacaagga tggtaataaa ctcgaccttt atggcaaggt taccgctcta cgttatttta
       61 ctgatgataa gcgtgacgat ggtgataaaa cttatgcccg tctcggcttt aaaggagaaa
      121 cgcaaatcaa tgatcaaatg attggttttg gtcactggga atatgatttt aaaggctata
      181 acgatgaagc caacggctcg cgcggcaaga atctctgatt gagttaagtg cccatcacaa
      241 tatgatcact gaccttatat tacacaatca tcccaggatg aaaacaatca ctttaaacga
      301 caaccatatt gcacatttaa acgccaaaaa cactacaaaa ctggaatatt taaacttaag
      361 caataaccat ttactgccaa ccaatgacat tgatcaacta atatcatcaa aacatctttg
      421 gcatgtatta gttaacggca tcaacaatga tccacttgca caaatgcagt actggactgc
      481 agtaagaaat ataattgatg acactaatga agtgaccatt gatttatcag gacttaattt
      541 aaccactcaa ccaccagggc tgcaaaactt cacctctatc aatcttgata ataaccaact
      601 cacacatttt gatgcaacca actacgatag actcgtaaag ctaagtctga atagtaatac
      661 tcttgactca ataaattttc ctc
//
LOCUS       DAPGUL010000349          678 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.355, whole genome shotgun sequence.
ACCESSION   DAPGUL010000349 DAPGUL010000000
VERSION     DAPGUL010000349.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..678
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.355"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..124
                     /locus_tag="RHX21_004964"
     CDS             <1..124
                     /locus_tag="RHX21_004964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF957 domain-containing protein"
                     /protein_id="HDV1989985.1"
                     /translation="GIIFDNNEDKTDSAALLPCIEQAREDIRTLRQLQLQHQNR"
     gene            221..>678
                     /locus_tag="RHX21_004965"
     CDS             221..>678
                     /locus_tag="RHX21_004965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
                     /protein_id="HDV1989986.1"
                     /translation="MSEITVSRPEVVNENTDVICSTSVRSRSLEYDNFPEISEANILS
                     TFEQLHQNKDEVFERGVINVFKGLSWDYKTNSPCKFGSKIIVNNLVRWDQWGFHLISG
                     MQADRLADLERMLHLLSGKPIPDNRGNITINLDDHIQSVQGKGRYEDEMF"
BASE COUNT          201 a          162 c          159 g          156 t
ORIGIN      
        1 gggaattatc tttgacaaca atgaggataa aacggattca gcagcactgt tgccctgtat
       61 cgaacaggcc agagaggata tccgtaccct gcgccaactg cagcttcagc accagaaccg
      121 gtgagtctca ctcatcatct cactcaccag acttcattcc actgacgcca gcctgaacac
      181 ggctggcgtt ttcatttatc tgcaaaaagg aatatcgatt atgtctgaaa tcacagtctc
      241 ccgtccggaa gtggtcaacg agaatacgga cgttatctgc tccacctcag tcaggtccag
      301 gtcactggaa tatgataatt ttccggaaat cagcgaagcg aacattctga gcacatttga
      361 acaactgcac cagaacaaag atgaagtgtt tgaacgggga gtgatcaacg tcttcaaagg
      421 gctgagctgg gattacaaaa ccaactcacc ctgtaaattt ggcagtaaaa ttatcgtcaa
      481 caatctggtg agatgggacc agtggggatt tcatcttatc agtggaatgc aggcagatcg
      541 cctggctgac ctggaaagaa tgttgcatct gctcagcggt aaaccgatcc ccgacaaccg
      601 agggaatatc accattaatc tggatgacca catacagtcc gttcagggta aaggacgcta
      661 tgaagatgag atgttcat
//
LOCUS       DAPGUL010000350          677 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.356, whole genome shotgun sequence.
ACCESSION   DAPGUL010000350 DAPGUL010000000
VERSION     DAPGUL010000350.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..677
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.356"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..675
                     /locus_tag="RHX21_004966"
     CDS             <1..675
                     /locus_tag="RHX21_004966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin"
                     /protein_id="HDV1989987.1"
                     /translation="TLVCAEQPHGFIDYRHEYLDDTRTHADRVEFGTFFSNGIGLMGE
                     LRYNTDEGDKDKWDPSQFGNNGTGLSVVYRFKPLDDKKFWLEPMFWLDTTQYWSTYEY
                     GLSAGYDFSKEWKVSGRFRYDMDKATDKSKGYGNDDRNNRRYDVWIDYRPQKTNFQYQ
                     LNLVYYNNGYLTWNDGHKNYTASFKVGYKMGSWIPYMSIADYKGVDKTSSNRQIRWRW
                     GLTYTF"
BASE COUNT          206 a          127 c          149 g          195 t
ORIGIN      
        1 acactagtct gtgcagaaca gccgcatgga tttattgatt atcgtcatga gtatcttgat
       61 gatactcgca cccacgcgga ccgcgttgaa tttggtacat tttttagtaa tggtatcggt
      121 ttgatgggag aattacgcta taacaccgat gaaggtgata aagataagtg ggacccctca
      181 caatttggca ataacggaac aggattatct gttgtttacc gctttaagcc gctggatgac
      241 aaaaaattct ggttagaacc catgttctgg cttgatacca cgcaatattg gtcaacttac
      301 gaatatggtc tttctgcggg ttatgatttc agcaaagaat ggaaagtttc gggtcgtttt
      361 cgttatgaca tggataaagc taccgataaa tccaaaggtt atggcaacga tgatcgtaat
      421 aaccgccgtt acgatgtgtg gatcgactat cgaccacaaa aaaccaactt ccaatatcag
      481 ttaaacctgg tctattacaa taatggttat ttaacctgga atgatggcca taaaaactat
      541 accgcatcat ttaaagtagg gtacaaaatg ggatcgtgga taccctatat gagtattgcg
      601 gattataaag gtgtggataa aacatcaagt aatcgccaaa tccgctggcg ctggggtctg
      661 acttatactt tctaatc
//
LOCUS       DAPGUL010000351          675 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.357, whole genome shotgun sequence.
ACCESSION   DAPGUL010000351 DAPGUL010000000
VERSION     DAPGUL010000351.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..675
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.357"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>675
                     /locus_tag="RHX21_004967"
     CDS             <1..>675
                     /locus_tag="RHX21_004967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-phosphate galactose phosphotransferase"
                     /protein_id="HDV1989988.1"
                     /translation="WYGIRLRHYFYRKTFWFELKEILRTLVIFAVIEMAVIAFAKWYF
                     SRYVWLLTWVMAIFLVPLARIAIKWLLMKWGLWLRDTWIIGSGKNAYEAYKAITSERN
                     LGLNVVGFVTDEQMQGEQRKTIDELPIIIGSIDWLNSKDKRTQFIVAVESEQSDIRNK
                     WLREFMIKGYRYVSVIPTLRGMPLDSTDMSFIFSHEVMIFRVQQNLAKWSSRIIKRCF
                     DLFGSIC"
BASE COUNT          204 a           94 c          156 g          221 t
ORIGIN      
        1 tggtatggaa taaggttaag gcattatttc tatcgtaaaa cattttggtt tgagcttaaa
       61 gaaatattga ggacactagt catttttgct gttattgaaa tggcagtgat agcatttgca
      121 aaatggtatt tctcacgcta tgtttggttg ttaacatggg ttatggcaat attcctcgta
      181 ccattagctc gtattgccat aaagtggctg ttgatgaaat ggggtttatg gttgcgagat
      241 acttggatta ttggaagcgg gaaaaacgct tatgaagctt ataaagcaat cacaagcgag
      301 cgtaatcttg gattaaatgt agtaggtttt gtcactgatg aacaaatgca aggagagcaa
      361 cgtaaaacaa ttgatgagct tccaataatt ataggaagta tcgattggtt aaatagtaaa
      421 gataaacgaa cccaatttat cgtagctgtt gaatctgaac aaagtgatat tcgcaacaaa
      481 tggttacgcg agttcatgat taaagggtat cgttacgttt cggtaatacc tacgttaaga
      541 gggatgcctc tggatagtac agatatgtcc ttcattttta gtcatgaagt tatgattttc
      601 cgtgtccagc agaatctggc caagtggtca tctcggataa ttaagagatg ttttgatctt
      661 ttcgggtcta tttgc
//
LOCUS       DAPGUL010000352          652 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.358, whole genome shotgun sequence.
ACCESSION   DAPGUL010000352 DAPGUL010000000
VERSION     DAPGUL010000352.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..652
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.358"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>652
                     /locus_tag="RHX21_004968"
     CDS             <1..>652
                     /locus_tag="RHX21_004968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HDV1989989.1"
                     /translation="YGYDEKGRLTGERQTVHHPQTEALLWQHETRHAYNAQGLANRCI
                     PDSLPAVEWLTYGSGYLAGMKLGDTPLVEYTRDRLHRETLRSFGRYELTTAYTPAGQL
                     QSQHLNSLLSDRDYTWNDNGELIRISSPRQTRSYSYSTTGRLTGVHTTAANLDIRIPY
                     ATDPAGNRLPDPELHPDSTLSMWPDNRIARDAHYLYRYDRYGRLTEKTDLIPEGGIR"
BASE COUNT          148 a          223 c          186 g           95 t
ORIGIN      
        1 attacgggta tgatgagaaa ggccggctga ccggtgagcg tcagacggtg catcacccgc
       61 agacggaagc actgctctgg cagcatgaga ccagacatgc gtacaacgcg caggggctgg
      121 cgaaccgctg tataccggac agcctgcccg ccgtggaatg gctgacctac ggcagcggtt
      181 acctggcagg catgaaactc ggcgacacac cgctggtgga gtacacccgc gaccgcctgc
      241 accgggaaac gctgcgcagc ttcggccgtt atgaactcac caccgcttat acccctgccg
      301 ggcagttaca gagccagcac ctgaacagcc tgctgtctga ccgcgattac acctggaacg
      361 acaacggcga actcatccgc atcagcagcc cgcgccagac ccggagttac agctacagca
      421 ccaccggcag gctgaccggc gttcacacca ccgcagcgaa ccttgatatc cgcatcccgt
      481 atgccacaga cccggcaggt aaccgcctgc ccgacccgga gctgcacccg gacagcaccc
      541 tcagcatgtg gccggataac cgtatcgccc gtgacgcgca ctatctttac cggtatgacc
      601 gttacggcag gctgacggag aaaaccgacc tcatcccgga agggggtatc cg
//
LOCUS       DAPGUL010000353          635 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.359, whole genome shotgun sequence.
ACCESSION   DAPGUL010000353 DAPGUL010000000
VERSION     DAPGUL010000353.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..635
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.359"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            35..>635
                     /locus_tag="RHX21_004969"
     CDS             35..>635
                     /locus_tag="RHX21_004969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HDV1989990.1"
                     /translation="MTKSETFMIPNHKAAKLSELDMMIVNSVPPGGNWKNIPLDVPSK
                     RIEQIRDSYAQGKGSRSTYYGRLLPDMPAYTINTYFNRPGNGCHIHYEQDRVLSQREA
                     ARLQSFPDDFIFFGGQTAINTQIGNAVPPFLAFLIAKEIEKAIGNTGYYIDLFSGAGG
                     LGLGFKWAGWTPLLANDIEEKYLQTYSNNVHKEVLCGSIS"
BASE COUNT          214 a          107 c          133 g          181 t
ORIGIN      
        1 gaaaaagaaa gtttattgag gatttttcaa cattatgact aaaagtgaaa catttatgat
       61 tcccaatcac aaggcagcaa agctaagtga attggatatg atgattgtta actcagtacc
      121 gccaggtggc aactggaaaa atattccttt agatgtaccg tctaaaagaa tagagcaaat
      181 tagggatagt tatgcacaag gaaaaggaag ccgttcaaca tactacggta gattacttcc
      241 agatatgcct gcatatacta tcaatacata ttttaaccga cctgggaatg gttgccatat
      301 tcactatgag caagatcgtg ttctatccca gagagaagct gcaagactac aatcgttccc
      361 ggatgatttt attttcttcg gaggtcaaac agcaattaat acccaaatcg gtaatgcagt
      421 gcccccattt ttagcttttc tgattgcgaa agaaatagag aaggcgatag gtaatactgg
      481 ttattatatc gatttatttt ccggagctgg agggctggga ctaggattca aatgggctgg
      541 atggactcca ttattggcga atgatattga agaaaaatat ctacaaacat attcaaacaa
      601 tgttcacaaa gaagttttat gtggcagcat ttctg
//
LOCUS       DAPGUL010000354          612 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.360, whole genome shotgun sequence.
ACCESSION   DAPGUL010000354 DAPGUL010000000
VERSION     DAPGUL010000354.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 612)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 612)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..612
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.360"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..557
                     /locus_tag="RHX21_004970"
     CDS             <1..557
                     /locus_tag="RHX21_004970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001423835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HDV1989991.1"
                     /translation="RQNVFEVGTSAAYLFYAQKTTDGQNLTVNGSVNCTTLNQSSDRR
                     LKENIEIIDNATDAIRKINGYTYTLKENGAHCAGVIAQEVEEAIPEAVGSFIHYGEEL
                     QGPTVDGNELREETRYLNVDYAAVTGLLVQVARETDDRVTALEEENTTLRQNLATAGT
                     RISTLENQVSELVALVRQLTGSEH"
BASE COUNT          176 a          147 c          160 g          129 t
ORIGIN      
        1 ctcgacaaaa cgtttttgag gttggcacgt ctgctgcgta tctgttttat gcgcaaaaaa
       61 caacagacgg gcaaaacctt actgtaaacg gaagtgttaa ctgcaccaca ctgaatcagt
      121 catcagaccg cagactgaaa gaaaatatcg agattatcga taacgcgact gacgcaatcc
      181 gcaaaattaa tggatacacg tacacgctca aggagaatgg ggcacattgc gccggggtta
      241 tagcccagga agttgaagag gccatcccgg aggccgttgg ttcattcatc cattacggtg
      301 aagagttgca aggcccgacc gttgacggca acgagctacg cgaagaaacg cgctatctta
      361 atgttgacta cgccgccgtg acgggtttac ttgttcaggt cgcccgtgaa acagatgatc
      421 gcgttaccgc gctggaagag gaaaacacaa cgctacgtca aaatctggca acagcaggca
      481 cccggatcag cactctggaa aatcaggtaa gcgaactggt tgcacttgtc cggcagttaa
      541 caggaagcga acattgatat ccttcaagct ctgaaggagg ctgttcccgg tacgttcaga
      601 ctgttgttga gc
//
LOCUS       DAPGUL010000355          608 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.361, whole genome shotgun sequence.
ACCESSION   DAPGUL010000355 DAPGUL010000000
VERSION     DAPGUL010000355.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 608)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 608)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..608
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.361"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..506)
                     /gene="fimE"
                     /locus_tag="RHX21_004971"
     CDS             complement(<1..506)
                     /gene="fimE"
                     /locus_tag="RHX21_004971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418733.1"
                     /note="upgraded from regulatory protein to switch DNA
                     invertase; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria switch DNA invertase FimE"
                     /protein_id="HDV1989992.1"
                     /translation="MSKRRYLTGKEVQAMMQAVCYGATGARDYCLILLAYRHGMRISE
                     LLDLHYQDLDLNEGRINIRRLKNGFSTVHPLRFDEREAVERWTQERANWKGADRTDAI
                     FISRRGSRLSRQQAYRIIRDAGIEAGTVTQTHPHMLRHACGYELAERGADTRLIQDYL
                     GHRNIRHTV"
BASE COUNT          182 a          157 c          127 g          142 t
ORIGIN      
        1 acagtatggc gaatatttcg atgcccgaga taatcctgaa ttaaacgggt atctgcacca
       61 cgctccgcca gttcataacc gcaagcatgc cttaacatat gaggatgagt ctgcgttacg
      121 gttccagctt caataccggc atcgcgaata atgcgatagg cctgctggcg agaaagccga
      181 ctcccgcggc gagaaataaa tatagcgtcg gtccggtcag cgcctttcca gttagcacgt
      241 tcctgggtcc agcgttccac ggcttcacgc tcatcaaaac gtaacgggtg aacggtagaa
      301 aatccgttct tcagtcggcg aatatttatt cgaccttcat taaggtcaag atcctgataa
      361 tgcagatcaa gcagttcact aatacgcatc ccatgccgat atgccaacag aataagacaa
      421 taatctctgg ctcccgttgc cccgtaacaa accgcctgca tcatggcctg aacttcttta
      481 ccggtaagat aacgacgttt actcacaata gtagtactcc taactgagat atatttgaat
      541 gaatacctat aggaaacctc aatcggtcaa aattagccca atagataaaa agataaccac
      601 acacggag
//
LOCUS       DAPGUL010000356          607 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.362, whole genome shotgun sequence.
ACCESSION   DAPGUL010000356 DAPGUL010000000
VERSION     DAPGUL010000356.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..607
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.362"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..488
                     /locus_tag="RHX21_004972"
     CDS             <1..488
                     /locus_tag="RHX21_004972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDV1989993.1"
                     /translation="TETIEIFNNSDEWANQLKHLLSKGENLALLHGLTPDILDRIYAY
                     AFDYHEKGNVTDAEIYYKFLCIYAFENHEYLEGFASVCQSKKKYQQAYDLYKLSYNYF
                     PYDDYSVIYRMGQCQIGAKNIDNAMQCFYHIINNCEDDSVKSKAQAYIELLNDNSEDN
                     G"
BASE COUNT          223 a           94 c          102 g          188 t
ORIGIN      
        1 gcacagaaac aattgaaata ttcaataata gtgatgaatg ggcaaatcaa ctaaaacacc
       61 tattatcgaa aggagaaaat ctggcattac tacatggttt aactcctgat atccttgata
      121 gaatatatgc atatgcattc gactaccatg aaaagggtaa tgtaacggac gcagaaattt
      181 attataaatt tttgtgcatt tatgcgttcg aaaatcatga gtatctagaa ggttttgcat
      241 cagtatgtca gtcaaaaaag aaatatcaac aagcatatga cctttacaaa ctaagttaca
      301 attacttccc gtatgatgac tattcagtta tttatcgtat gggtcaatgt cagattgggg
      361 ctaaaaatat cgataacgca atgcaatgtt tctatcacat tattaacaat tgtgaggatg
      421 atagtgttaa gagtaaagcg caggcatata ttgaactctt aaacgataat tcagaagata
      481 atggctaagc attacaatca tttggttaaa tttgctggtt atagtgcagt taaccactat
      541 aaccagcacc tcttatgttt tcttaaatca gcatcttaaa acagttaaga gcatactata
      601 aatcatt
//
LOCUS       DAPGUL010000357          605 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.363, whole genome shotgun sequence.
ACCESSION   DAPGUL010000357 DAPGUL010000000
VERSION     DAPGUL010000357.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 605)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 605)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..605
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.363"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>605
                     /locus_tag="RHX21_004973"
     CDS             <1..>605
                     /locus_tag="RHX21_004973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989994.1"
                     /translation="ASKLMTEFDDNGKIIFNLNALKYTKASYFEILGEKYIKITTSSP
                     WLLEKLGKYIFSSRAPQVLELAIGWRGALSESIKGVKFCIWFSVAWRTIEFIMSSERD
                     LVNFLGDFSMDVAKAVIAGGVATAIGSLASFACVSFGFPVILVGGAILLTGIVCTVVL
                     NEIDAQCHLSEKLKYAIRDGLKRQQELDKWKRENMTPFMYV"
BASE COUNT          189 a           96 c          132 g          188 t
ORIGIN      
        1 cgcgagtaaa ttaatgactg agtttgatga caatgggaaa attatattta accttaatgc
       61 cttaaagtat acaaaagcaa gttactttga aatacttgga gagaaatata taaaaatcac
      121 aacatccagc ccctggcttt tagaaaagct cggtaaatat attttctctt cacgagcgcc
      181 tcaagttctg gaactcgcta ttggctggcg aggagcttta tctgaatcaa taaaaggagt
      241 taagttctgt atctggtttt cagtagcctg gagaaccata gaatttatta tgagttcaga
      301 gcgagatctg gttaattttc ttggcgattt ttcaatggat gtggccaaag cagttatagc
      361 cggtggtgtt gcaaccgcta ttggaagcct ggcttctttt gcctgtgtta gctttggctt
      421 tccagtaatt cttgtcggag gagcaatttt actgacaggg atagtgtgta cagttgtttt
      481 aaatgaaatc gatgctcaat gccatttatc agaaaaatta aaatatgcaa ttagagatgg
      541 actaaaacgg caacaggaac ttgataaatg gaaaagggaa aacatgactc catttatgta
      601 tgttc
//
LOCUS       DAPGUL010000358          604 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.364, whole genome shotgun sequence.
ACCESSION   DAPGUL010000358 DAPGUL010000000
VERSION     DAPGUL010000358.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 604)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 604)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..604
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.364"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..208)
                     /locus_tag="RHX21_004974"
     CDS             complement(<1..208)
                     /locus_tag="RHX21_004974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1989995.1"
                     /translation="MKPRNINNSLSLQPLVPDQENKNKKNEEKSVNPVKITMGSGLNY
                     IEQESLGGKYLIHDLSIKIADISEE"
     gene            402..604
                     /locus_tag="RHX21_004975"
                     /pseudo
     CDS             402..604
                     /locus_tag="RHX21_004975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417326.2"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT          196 a           93 c          105 g          210 t
ORIGIN      
        1 tctcttcaga aatatccgct atctttattg acaaatcatg tattagatat tttcctccaa
       61 gagattcttg ttcaatataa tttaaaccag accccattgt gattttaact ggattaacgg
      121 atttctcttc atttttctta tttttgttct cctgatcagg aactaatggt tgcagtgata
      181 ggctattatt aatatttcgt ggcttcattt tacatttctc tcatttgatt agagcaaaat
      241 ccgaattcgc agcttctgat aatgtcaaat atcaccttat ggagacgtta cgtagaatga
      301 ctatatttgt tatcggcaca ttaggggtat taattttagt attgatggaa ggtgattatt
      361 gaacagtaac atcgagtcac ggtaaaaatg tgaggtatac aatggacatt gagttttcgc
      421 agattcatga aatggtctat atgcatgata ttgtaaattc ggactcgaaa aagaaaccaa
      481 ggattccgtt aaaaaattcc ttaatgctga gaaggttctc acgcaaacaa catcatggac
      541 attaaattca agatatgtga atgttaattc tgtcaataaa gtcaacgtaa agagtaaagt
      601 taaa
//
LOCUS       DAPGUL010000359          599 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.365, whole genome shotgun sequence.
ACCESSION   DAPGUL010000359 DAPGUL010000000
VERSION     DAPGUL010000359.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 599)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 599)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..599
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.365"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            397..522
                     /locus_tag="RHX21_004976"
     CDS             397..522
                     /locus_tag="RHX21_004976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001422407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
                     /protein_id="HDV1989996.1"
                     /translation="MVFPKVSDGITQVSVDNNLISRVDSSPSKAMTISIYRNKIW"
BASE COUNT          201 a          110 c          108 g          180 t
ORIGIN      
        1 aataagatag gttttatcat gatagaaaaa aatcagggaa ctggtaaccc acccattcgg
       61 cataaattag agtttatatc gactaatatt gcagagtttc tagacaactt tacgaaaatt
      121 acagattcca gactttgcaa aggtttcagt gactgggcta attcagtcaa agaaggcgca
      181 tcgaatgact tcaaaaaaaa tgtggatata gcattggtga gattgtttaa atgtgttgaa
      241 ctccacaata gtaaacttga cttaacagat cttcacttgg ggtctttgcc acctcttcca
      301 tcctggattg aggtgcttta tcttcgtcat aatggccttg ccacaataca ggttcccaaa
      361 ttctgcaaag aattagagct cgatttcaat aattatatgg tatttccaaa agtatccgat
      421 ggaattaccc aggtctccgt agataataat ctgatatcgc gtgttgactc atctccgtca
      481 aaggctatga caatttctat ttatcgcaat aaaatatggt aaataccagc aatgcctgag
      541 actactaagc tgtttaattg tggcgataat aagataaaag aaattcaata cttcccaaa
//
LOCUS       DAPGUL010000360          590 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.366, whole genome shotgun sequence.
ACCESSION   DAPGUL010000360 DAPGUL010000000
VERSION     DAPGUL010000360.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..590
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.366"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            250..>590
                     /locus_tag="RHX21_004977"
     CDS             250..>590
                     /locus_tag="RHX21_004977"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HDV1989997.1"
                     /translation="MANVIIFTNEYFPFKGGIGRYCEEVINEIKLQHKVTLVGPAYDS
                     SLTRDKRSEGIRLELFPGGQFKYWHLPKLIKKVSSIDFEQYDYVLVADWPFWVAIEFL
                     NRFSFKRKIRF"
BASE COUNT          174 a           94 c          121 g          201 t
ORIGIN      
        1 gaaaaatctt caacttcggc cctatatcgc aactgctaaa catgttccca attatagttt
       61 ctacgagtgt tatgtttgtc gcgacatatt tttggtcaat caacaatggc ttgttagaca
      121 ttattatcaa gatcgtagtc ggtgcgatag tatacattat ttcctgcttt gttctcaaag
      181 ttgaatctgt tcaggaaatt tggtcctata tgctaggtaa aattaaggga aaaaacagga
      241 gaagtacttg tggctaatgt aatcattttt actaatgaat attttccctt caaaggaggg
      301 atcgggcgct actgtgaaga agttattaat gaaataaaac ttcagcacaa ggttacgctt
      361 gtggggcctg cgtacgattc atctttaact cgcgataaac gttctgaagg aatccgttta
      421 gagctttttc ctggtggtca atttaagtat tggcatttgc caaaactcat caagaaagtg
      481 agctcgatcg attttgaaca atatgattat gtcttggttg cagattggcc attctgggta
      541 gcaattgaat ttttgaatag atttagtttt aaacggaaaa ttcgttttaa
//
LOCUS       DAPGUL010000361          586 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.367, whole genome shotgun sequence.
ACCESSION   DAPGUL010000361 DAPGUL010000000
VERSION     DAPGUL010000361.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..586
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.367"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..118)
                     /locus_tag="RHX21_004978"
     CDS             complement(<1..118)
                     /locus_tag="RHX21_004978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDV1989998.1"
                     /translation="MKLRHLDIFYAVMTCGSLTRAAEVLHISQPAASKALKHA"
     gene            complement(349..>586)
                     /locus_tag="RHX21_004979"
     CDS             complement(349..>586)
                     /locus_tag="RHX21_004979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HDV1989999.1"
                     /translation="VTFKMMGKDYDAVVISAGHCGFGMGATPTAIANMQTVTKAFGPS
                     HKAFLVVPMVGAFIVDISNSILIKIFIEIGTYFT"
BASE COUNT          189 a          106 c          118 g          173 t
ORIGIN      
        1 cagcatgttt gagtgcttta ctcgccgcgg gttgagaaat atgtaaaact tcagccgcac
       61 gcgttaagga accacaagtc attacagcat aaaagatatc gagatgtctt aatttcattc
      121 catgtagcct actgattatt tatttctacg gactattcta acgaataaag tataaataat
      181 cagatatact cgtcataatt caaattttgg tttagttgtc acgagaatta attcgtaaac
      241 gtgcaagcta aatagattga ctaggggaat atacggggta agaaagcggc tcggcatact
      301 gccctataat aaattgttag gagaagtacg ccgagtagtg tgtagctatt aggtaaagta
      361 tgtaccaatt tcaataaata ttttaattaa gatactgttt gaaatatcaa caataaaggc
      421 accgaccata ggaacgacaa ggaaagcttt atgtgatggt ccaaatgctt ttgtgactgt
      481 ttgcatattc gcaattgctg ttggtgttgc tcccatacca aagccacagt gacccgcgct
      541 gatcacgaca gcatcataat ctttgcccat cattttgaag gtgaca
//
LOCUS       DAPGUL010000362          582 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.368, whole genome shotgun sequence.
ACCESSION   DAPGUL010000362 DAPGUL010000000
VERSION     DAPGUL010000362.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..582
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.368"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            11..>582
                     /locus_tag="RHX21_004980"
     CDS             11..>582
                     /locus_tag="RHX21_004980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001566505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Alw26I/Eco31I/Esp3I family type II restriction
                     endonuclease"
                     /protein_id="HDV1990000.1"
                     /translation="MKMGKIAVTPNNDKAASHSKDENLATNTIKKNVKPKYGDAAFLE
                     YTRLIVNHPNYFGMPDPFGEKGEIQWEAPSNRASGKFKHTHQRRYEWWKNKARSIGID
                     PDTEKAWISKTAKLIHPLGVKPCKKCGKEMELSYSYPNEHFFSRVRKLNYIDETFELS
                     QNEHIVDLLTRLDDRFGERIYLDLPHLFST"
BASE COUNT          218 a           94 c          111 g          159 t
ORIGIN      
        1 tggagaattt atgaaaatgg gaaaaattgc agttactcct aataatgata aagcagccag
       61 ccactctaaa gatgaaaatt tagccacaaa tacaattaag aaaaacgtaa aacctaaata
      121 tggcgatgcg gcatttttag agtacactcg actaatagtt aaccacccga attattttgg
      181 aatgccagat ccctttgggg aaaaaggtga gattcaatgg gaagctccat caaatagggc
      241 atcggggaaa tttaaacaca ctcatcaacg gcgctatgaa tggtggaaaa ataaagccag
      301 aagtattggg atagaccctg acactgaaaa agcatggatt agtaaaacag ctaaactaat
      361 tcatccactt ggagttaaac catgcaagaa atgcggtaaa gaaatggaat tatcttactc
      421 ctacccaaat gagcatttct tttctcgggt taggaaactt aattatatag atgagacttt
      481 tgagctatct caaaatgaac acatagttga tttgttgact cgtttagatg atagatttgg
      541 tgaaagaata tatttagatt taccacattt attttctaca aa
//
LOCUS       DAPGUL010000363          559 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.369, whole genome shotgun sequence.
ACCESSION   DAPGUL010000363 DAPGUL010000000
VERSION     DAPGUL010000363.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..559
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.369"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>559
                     /locus_tag="RHX21_004981"
     CDS             <1..>559
                     /locus_tag="RHX21_004981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDV1990001.1"
                     /translation="LEARFTNSTKNKWGGYGINFVNAQNCHVYNIWGKGWTQLIGMGS
                     DIPPETPSNHLCSAKYLHVLEPDLVRTYYSIGFIANSTDCSIEHAIQYVPMTSGSLNG
                     SGAALNLCEDCLISNITIPHLGKTQTSEGIMVNNSSGCRVNNIMIGDAKIAVSLFFSD
                     KSTLNPEKPNFIDTVTGVNCNSVISV"
BASE COUNT          173 a           88 c          114 g          184 t
ORIGIN      
        1 ttagaggcga gatttactaa tagtacaaaa aataaatggg gggggtatgg catcaacttt
       61 gtcaatgctc agaattgtca tgtttataat atatggggaa agggatggac tcaattgatt
      121 gggatgggat cagatattcc acctgagact ccctcaaatc atttatgttc tgccaaatat
      181 ttacatgtgt tggaaccgga tttggtgaga acctattatt ctataggttt cattgcaaat
      241 tctacagact gctcaataga acacgcaata caatacgtac cgatgacaag cggttcatta
      301 aatggaagtg gtgctgctct aaatttatgc gaagattgtc ttatcagtaa tattacgatt
      361 cctcacttgg ggaaaactca aacctctgaa gggattatgg ttaataactc ttctggttgt
      421 cgtgttaata atattatgat tggtgatgct aaaattgcgg tgtctttatt ctttagcgac
      481 aaatctactc ttaaccctga aaaacctaat tttatagata ctgtaacagg cgtaaattgt
      541 aattcagtaa tttcggttt
//
LOCUS       DAPGUL010000364          556 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.370, whole genome shotgun sequence.
ACCESSION   DAPGUL010000364 DAPGUL010000000
VERSION     DAPGUL010000364.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 556)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 556)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..556
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.370"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            1..556
                     /locus_tag="RHX21_004982"
                     /pseudo
     CDS             1..556
                     /locus_tag="RHX21_004982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313048.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="SopA family protein"
BASE COUNT          183 a           83 c          103 g          187 t
ORIGIN      
        1 tctcaatcag taatgatact ataagtgtaa aattctacag aaatgaaaaa aattgaatgc
       61 gcttgcaatt ttctgatgga taaagatgcg caggggtata tcgacctgtc tgatttggat
      121 ttaacaagtt gtcattttaa aggtgacgtt atatcgaagg tgtctttttt atcatcaaat
      181 ctacaacatg taacattcga atgtaaagaa attggggatt gcaattttac tactgcaata
      241 gttgataatg tcatatttag atgtcgacgt ttacacaatg tgatttttat caaagcgagt
      301 ggtgaatgtg tcgatttcag caaaaatatt cttgatacag ttgacttctc gcagagtcaa
      361 cttactcaga gtaattttcg cgaatatcag attagaaatt caaacttcga taattgttat
      421 ctttacgctt cgcacttcac cagagcagag tttctgtctg ccaaagaaat atcatttatt
      481 aaatcgaata tgacagctgt tatgtttgat catgtgcgaa tatcgacagg gaattttaaa
      541 gattgcatta cagaac
//
LOCUS       DAPGUL010000365          537 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.372, whole genome shotgun sequence.
ACCESSION   DAPGUL010000365 DAPGUL010000000
VERSION     DAPGUL010000365.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..537
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.372"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(26..>537)
                     /locus_tag="RHX21_004983"
     CDS             complement(26..>537)
                     /locus_tag="RHX21_004983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HDV1990002.1"
                     /translation="GGPPCQGFSTAGNARTMDDPRNSLFMHYKSLLNEIKPNGFIFEN
                     VAGLLNMEKGKVFERVKEEFSSTMKTMNGWILNSEHYAIPQRRKRVILVGSNDPLFSI
                     EPPQKLTEDKESWVSVKDALSDLPPLQHGEDGSGKYYIHHPENDYQLFMRGNITPSEY
                     YERNIKPSL"
BASE COUNT          163 a          100 c           89 g          185 t
ORIGIN      
        1 aattatagag taagacatag ccctcttata aagagggctt tatattcctt tcataatatt
       61 ctgaaggagt aatattacct ctcatgaata attgatagtc attttcgggg tgatggatat
      121 aatatttacc acttccatct tcaccatgtt gcaaaggagg cagatcagat aatgcatcct
      181 ttacagatac ccaagattcc ttatcttctg ttaatttttg tggaggttca attgaaaata
      241 aagggtcgtt tgaaccaacc aatataaccc tttttcggcg ctgagggatt gcataatgtt
      301 cagagtttaa tatccatcca ttcatagttt tcatggttga tgagaattct tctttgactc
      361 tttcaaagac cttacctttt tccatattca acaaaccagc aacattttca aaaataaaac
      421 cgtttggttt tatctcattt aagagagatt tataatgcat aaaaagtgaa tttcttggat
      481 catccattgt tctggcattt cctgccgtag aaaatccctg gcatgggggt ccaccaa
//
LOCUS       DAPGUL010000366          531 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.373, whole genome shotgun sequence.
ACCESSION   DAPGUL010000366 DAPGUL010000000
VERSION     DAPGUL010000366.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..531
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.373"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>531
                     /locus_tag="RHX21_004984"
     CDS             <1..>531
                     /locus_tag="RHX21_004984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS2 family transposase"
                     /protein_id="HDV1990003.1"
                     /translation="VKESNQRWCSDGFEFCCDNGERLRVTFALDCCDREALHWAVTTG
                     GFNSETVQDVMLGAVERRFGNDLPSSPVEWLTDNGSCYRANETRQFARMLGLEPKNTA
                     VRSPESNGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSP
                     REYLRQRACNGLSDNRC"
BASE COUNT          133 a          121 c          169 g          108 t
ORIGIN      
        1 gtgaaagaaa gcaatcagcg atggtgctct gacgggttcg agttctgctg tgataacgga
       61 gagagactgc gtgtcacgtt cgcgctggac tgctgtgatc gtgaggcact gcactgggcg
      121 gtcactaccg gcggcttcaa cagtgaaaca gtacaggacg tcatgctggg agcggtggaa
      181 cgccgcttcg gcaacgatct tccgtcgtct ccagtggagt ggctgacgga taatggttca
      241 tgctaccggg ctaatgaaac acgccagttc gcccggatgt tgggacttga accgaagaac
      301 acggcggtgc ggagtccgga gagtaacgga atagcagaga gcttcgtgaa aacgataaag
      361 cgtgactaca tcagtatcat gcccaaacca gacgggttaa cggcagcaaa gaaccttgca
      421 gaggcgttcg agcattataa cgaatggcat ccgcatagtg cgctgggtta tcgctcgcca
      481 cgggaatatc tgcggcagcg ggcttgtaat gggttaagtg ataacagatg t
//
LOCUS       DAPGUL010000367          520 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.374, whole genome shotgun sequence.
ACCESSION   DAPGUL010000367 DAPGUL010000000
VERSION     DAPGUL010000367.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 520)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 520)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..520
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.374"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..322)
                     /locus_tag="RHX21_004985"
     CDS             complement(<1..322)
                     /locus_tag="RHX21_004985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020218801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EscU/YscU/HrcU family type III secretion system
                     export apparatus switch protein"
                     /protein_id="HDV1990004.1"
                     /translation="MKSDVSNSRLMISNPTHIAIGIYFKPHLSPIPLISVRVTNEVAL
                     GVRKYAKEIGIPIITDKKLARKNYATHRRYDYVSFENIDEILRLLLWLEDVENAGQPV
                     QDEQL"
     gene            complement(319..>520)
                     /locus_tag="RHX21_004986"
     CDS             complement(319..>520)
                     /locus_tag="RHX21_004986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="EscU/YscU/HrcU family type III secretion system
                     export apparatus switch protein"
                     /protein_id="HDV1990005.1"
                     /translation="LFLLILYCLGSMIIVLIFDFIAEYFLFMKDMKMDKQEVKREYKE
                     QEGNPEIKSKRRERIRKFFLSN"
BASE COUNT          157 a          101 c           84 g          178 t
ORIGIN      
        1 agagctgttc atcttgaaca ggttgcccag cattctccac atcttcaagc cacagcagaa
       61 gacgtaatat ttcatctata ttttcgaagc taacataatc gtagcgacga tgggtagcat
      121 aattttttcg tgctaatttt ttatctgtga taattggtat tccgatttcc tttgcatatt
      181 tccttacgcc taaggccacc tcattagtta ctcttacaga aatcaatgga ataggtgaaa
      241 gatgtggctt aaagtatatc cctattgcaa tgtgagtagg gttggaaatc atcaaacgac
      301 tattactgac atcagacttc aattgctcag aaagaatttc ctgatgcgct ctctgcgttt
      361 agacttaatt tctggatttc cttcttgctc cttgtattct cttttaactt cttgtttatc
      421 cattttcata tctttcataa ataaaaaata ttcagcgata aaatcaaaaa ttaagacaat
      481 tatcatactg ccgagacaat acagtatgag aaggaatagc
//
LOCUS       DAPGUL010000368          516 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.375, whole genome shotgun sequence.
ACCESSION   DAPGUL010000368 DAPGUL010000000
VERSION     DAPGUL010000368.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..516
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.375"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..184)
                     /locus_tag="RHX21_004987"
     CDS             complement(<1..184)
                     /locus_tag="RHX21_004987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component-system connector protein YmgA"
                     /protein_id="HDV1990006.1"
                     /translation="MKTSDNERIKYEITGQAVIQILRMKINFSLQTLIKQLLVMKSAE
                     EDAFRRDLIDSIIRDFS"
     gene            complement(227..463)
                     /locus_tag="RHX21_004988"
     CDS             complement(227..463)
                     /locus_tag="RHX21_004988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component-system connector protein YcgZ"
                     /protein_id="HDV1990007.1"
                     /translation="MHQNSVTLDSAGAITRYFAKANLPTQQETLGEIVTEILKDGRNL
                     SRKSLCAKLLCRLEHATGEEEQKHYNALIGLLFE"
BASE COUNT          153 a          111 c           91 g          161 t
ORIGIN      
        1 tgctaaaatc acgaattatg ctgtcaatta aatcgcgtcg gaaagcatct tcctcagccg
       61 atttcattac gagtaattgc ttaataagag tctgcaatga aaaatttatc ttcatgcgca
      121 gtatctggat caccgcctgg ccagtaattt catattttat acgttcatta tcagatgtct
      181 tcataacgac ttcatagcta acctgttaaa taatcaggct gttgcattat tcaaaaagca
      241 acccaattag tgcattataa tgtttctgtt cctcttcccc agtcgcgtgt tccagtcggc
      301 aaagaagttt ggcacaaagc gactttcgac tcagattacg tccatctttc aaaatctcag
      361 tcacaatttc cccgagagtt tcctgctgag taggcaagtt agcttttgca aagtaacgag
      421 tgattgctcc cgcagaatct aaagtcactg aattttgatg catgctacgc ctctgttaaa
      481 aatgttaatc aatgttaagt gaggtaacaa tagcaa
//
LOCUS       DAPGUL010000369          501 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.377, whole genome shotgun sequence.
ACCESSION   DAPGUL010000369 DAPGUL010000000
VERSION     DAPGUL010000369.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.377"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(104..466)
                     /locus_tag="RHX21_004989"
     CDS             complement(104..466)
                     /locus_tag="RHX21_004989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001694203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1990008.1"
                     /translation="MGAHSTDVANDAVYSDKKKTSRFFYLLTPVRYLLAASLYLVVVI
                     PLGILAGFRFLLQFLGGIAVMGLTIAWYMGADVSGYIVLAAWIALTVCGCAEQIFEWW
                     IESRFAFRLFGIGRTPEE"
BASE COUNT          168 a          124 c           91 g          118 t
ORIGIN      
        1 cacaggaaaa aacatcgttt ttggacaatc atggataaaa tgttaacatt ttgaccataa
       61 ttgtctatcc tgcattgttc tttactgtct gtaagatcag cgctcattct tccggcgttc
      121 tcccgatacc aaaaagacgg aacgcaaaac ggctttcgat ccaccattca aaaatctgct
      181 ctgcgcaacc acaaacagtt aaggcgatcc atgcagcaag aacaatgtaa ccactgacat
      241 ctgcacccat gtaccaggcg atagttaacc ccatcactgc gataccgcct aaaaactgca
      301 acaagaaacg aaatcccgca agaatcccca atggaataac aacaaccaga taaagggaag
      361 cagccagaag gtatctgaca ggtgtcagca gataaaagaa cctagatgtt ttctttttgt
      421 cagaataaac ggcatcattt gcaacatctg ttgaatgagc gcccaggtct ctcctgatac
      481 gttgaaaatc cacgatgtta t
//
LOCUS       DAPGUL010000370          493 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.378, whole genome shotgun sequence.
ACCESSION   DAPGUL010000370 DAPGUL010000000
VERSION     DAPGUL010000370.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 493)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 493)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..493
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.378"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..>493)
                     /locus_tag="RHX21_004990"
     CDS             complement(<1..>493)
                     /locus_tag="RHX21_004990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418674.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDV1990009.1"
                     /translation="VIDSILETFLKSPYINDVRILDWCFNKRMQYFGDSEKIKYACSV
                     INHIDFSRDQSKDFSCDQSKIKIAETLFFNLDKEPYKNSRKLQELIWDKLVAYVNDFN
                     LSNQEKSRLILRLFDDVKLLFDEVPVSILVNDIFLKGFFMKQPDFAKWYFYQLLKKYE
                     GEQL"
BASE COUNT          171 a           91 c           65 g          166 t
ORIGIN      
        1 agctgttcgc cctcatactt cttaagtaat tgatagaagt accacttcgc aaaatcaggt
       61 tgcttcatga aaaaaccttt caaaaaaata tcatttacta aaatgctgac aggcacttca
      121 tcaaatagca acttaacatc atcaaataac cttagtatta agcgtgattt ttcttgattg
      181 cttaagttaa aatcattgac atatgcaacc aacttatccc aaatcaattc ctgtaattta
      241 cggctatttt tatagggttc tttatcgaga ttgaaaaata aggtctcagc tattttaatt
      301 ttagattgat cgcagctaaa atctttagat tgatcgcggc taaaatcaat atgatttatc
      361 acggagcatg catactttat cttttcagaa tcaccaaaat attgcattct tttattaaaa
      421 caccaatcca gtattcttac atcattaata tatggggatt ttaaaaaagt ctccagaatc
      481 gaatcgatga ccg
//
LOCUS       DAPGUL010000371          492 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.379, whole genome shotgun sequence.
ACCESSION   DAPGUL010000371 DAPGUL010000000
VERSION     DAPGUL010000371.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.379"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(165..>492)
                     /locus_tag="RHX21_004991"
     CDS             complement(165..>492)
                     /locus_tag="RHX21_004991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1990010.1"
                     /translation="NNMAIYWNSRASLFCSTELNSKSQSPALGLGHEFAHAQYYLLDK
                     ENFMALLSRTDKKYENKEEARVITIIESRAAKTLGECTRGAHSGLPFYRVDGPLQTMK
                     ITGTPE"
BASE COUNT          151 a          124 c           69 g          148 t
ORIGIN      
        1 cttgctaagc ggaactaacg tggtaacata cgatggaaga ttaattatct ctatcgtttt
       61 cacgctatct attccacaca attcattcac tcgccccatc cccagtaccg aaccagaaaa
      121 tagagacaat aaaaccatca aatatttcat cataaaaaac ctcactattc tggcgtaccc
      181 gttattttca tcgtctgcaa cggtccatcc acccgataaa aaggcagtcc actatgagct
      241 cctctggtac actcacctaa agttttcgcc gcacgcgatt caattattgt aataaccctt
      301 gcctcttctt tattctcata tttcttatct gttcggctta aaagagccat gaaattttcc
      361 ttatcaagaa ggtaatactg cgcatgagca aactcatgtc ccaaacctaa tgcaggcgat
      421 tgtgatttcg agtttaattc agttgaacaa aataaagatg ctctactatt ccaatatatc
      481 gccatattat tc
//
LOCUS       DAPGUL010000372          492 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.380, whole genome shotgun sequence.
ACCESSION   DAPGUL010000372 DAPGUL010000000
VERSION     DAPGUL010000372.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.380"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..>492)
                     /locus_tag="RHX21_004992"
     CDS             complement(<1..>492)
                     /locus_tag="RHX21_004992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HDV1990011.1"
                     /translation="WGVYALIYQTILYSIIVTVLMFFIAKWIPKLEFSMARAYSLFSF
                     GSKIFVANLVGVISDNSYAILIGKLFSSKEVGFFTQGRNLPDLLSVNLFNILQGVLFP
                     VMSSAQDDKERLLRIYKKSLNMTAFIVLPSMVGLVIIAEPFVRVFLTEKWLPSVFIIQ
                     WLAL"
BASE COUNT          185 a           93 c           71 g          143 t
ORIGIN      
        1 taatgcaagc cattgaataa taaatacact cggcaaccat ttttcagtca gaaatactct
       61 aacaaatggc tcggcaataa ttactaaccc aaccatagat ggcagtacaa taaatgcagt
      121 catatttaga cttttcttat atatccttaa taatctttct ttgtcatcct gtgcagatga
      181 cattacagga aaaagaactc cttgcaatat attgaaaaga ttaacagata acaagtctgg
      241 aagatttcgc ccttgcgtaa aaaaaccaac ttctttacta gaaaataact taccgataag
      301 aatagcgtat gagttgtctg aaatcacacc aactagatta gcaacgaata tctttgaacc
      361 aaaactgaat aaactatatg cccgtgccat tgaaaactct agttttggaa tccatttggc
      421 aatgaaaaac attagaacgg tcacaattat tgaatatagt atggtttgat agattaatgc
      481 atatactccc ca
//
LOCUS       DAPGUL010000373          486 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.381, whole genome shotgun sequence.
ACCESSION   DAPGUL010000373 DAPGUL010000000
VERSION     DAPGUL010000373.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.381"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(361..>486)
                     /locus_tag="RHX21_004993"
     CDS             complement(361..>486)
                     /locus_tag="RHX21_004993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417589.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator TdcR"
                     /protein_id="HDV1990012.1"
                     /translation="KHLFYQYFKISNTGIDHLEQLINVNFFSSDRTSFCECNRFP"
BASE COUNT          150 a           96 c           92 g          148 t
ORIGIN      
        1 tctttttacc gtccaataat taatatttct attgtgattg ttaaccactg cgtgcattgg
       61 cgggattgaa gggtgaaaaa tatgtgcaat tgggaagcct ttcattgatg cctgccttgt
      121 cgtcatgaca aacaataata gatgcttatt ttcctcgcac gacacttacg cactatcaaa
      181 aaacgctcat ttacccggcg ttacagtaaa cgaagcaaca ttctgtgtcc tacgctgatg
      241 taaagcacag tgaaaatccc ccttgttgac ttcgtctgac cttatcgcgg cgaccagcaa
      301 ttattcgttt tgtgatcctc aacacaaaat gctattcgtc gcctatgagg ggagaagaat
      361 ttatggaaaa cgattgcatt cacaaaatga cgtcctgtca gaagagaaaa agttgacgtt
      421 aatcaattgt tcgagatgat caatacctgt attcgaaatt ttaaaatatt gataaaataa
      481 atgttt
//
LOCUS       DAPGUL010000374          472 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.382, whole genome shotgun sequence.
ACCESSION   DAPGUL010000374 DAPGUL010000000
VERSION     DAPGUL010000374.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..472
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.382"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..>472
                     /locus_tag="RHX21_004994"
     rRNA            <1..>472
                     /locus_tag="RHX21_004994"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          118 a          113 c          142 g           99 t
ORIGIN      
        1 tgtcgtcagc tcgtgttgtg aaatgttggg ttaagtcccg caacgagcgc aacccttatc
       61 ctttgttgcc agcggtccgg ccgggaactc aaaggagact gccagtgata aactggagga
      121 aggtggggat gacgtcaagt catcatggcc cttacgacca gggctacaca cgtgctacaa
      181 tggcgcatac aaagagaagc gacctcgcga gagcaagcgg acctcataaa gtgcgtcgta
      241 gtccggattg gagtctgcaa ctcgactcca tgaagtcgga atcgctagta atcgtggatc
      301 agaatgccac ggtgaatacg ttcccgggcc ttgtacacac cgcccgtcac accatgggag
      361 tgggttgcaa aagaagtagg tagcttaacc ttcgggaggg cgcttaccac tttgtgattc
      421 atgactgggg tgaagtcgta acaaggtaac cgtaggggaa cctgcggttg ga
//
LOCUS       DAPGUL010000375          471 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.383, whole genome shotgun sequence.
ACCESSION   DAPGUL010000375 DAPGUL010000000
VERSION     DAPGUL010000375.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..471
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.383"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(<1..>471)
                     /locus_tag="RHX21_004995"
     rRNA            complement(<1..>471)
                     /locus_tag="RHX21_004995"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           87 a          152 c          100 g          132 t
ORIGIN      
        1 ccttctcccg aagttacggc accattttgc ctagttcctt cacccgagtt ctctcaagcg
       61 ccttggtatt ctctacctga ccacctgtgt cggtttgggg tacgatttga tgttacctga
      121 tgcttagagg cttttcctgg aagcagggca tttgttgctt cagcaccgta gtgcctcgtc
      181 atcacgcctc agccttgatt ttccggattt gcctggaaaa ccagcctaca cgcttaaacc
      241 gggacaaccg tcgcccggcc aacatagcct tctccgtccc cccttcgcag taacaccaag
      301 tacaggaata ttaacctgtt tcccatcgac tacgcctttc ggcctcgcct taggggtcga
      361 ctcaccctgc cccgattaac gttggacagg aacccttggt cttccggcga gcgggctttt
      421 cacccgcttt atcgttactt atgtcagcat tcgcacttct gatacctcca g
//
LOCUS       DAPGUL010000376          466 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.denovo.384, whole genome shotgun sequence.
ACCESSION   DAPGUL010000376 DAPGUL010000000
VERSION     DAPGUL010000376.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..466
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.denovo.384"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            <1..192
                     /locus_tag="RHX21_004996"
     CDS             <1..192
                     /locus_tag="RHX21_004996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017493091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HDV1990013.1"
                     /translation="QVDYYLLSKPGMTGLWQVSGRSDVDYDTRVYFDAWYVKNWSMWN
                     DIAILLKTVIVVLKKDGAY"
     gene            216..>466
                     /locus_tag="RHX21_004997"
     CDS             216..>466
                     /locus_tag="RHX21_004997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HDV1990014.1"
                     /translation="MNNVSLKEKTITSLIWNAIERFMVQGGQFVIKILIARQISPDDY
                     GLVGIVAVLLVLSDVIINGGFSQALIQKKDRTSLDYSTV"
BASE COUNT          146 a           62 c          104 g          154 t
ORIGIN      
        1 caagttgatt attatctttt gagtaagcct ggcatgactg ggctttggca ggttagcgga
       61 agaagtgatg ttgattatga tacccgtgtt tattttgacg catggtatgt taaaaattgg
      121 tctatgtgga atgatatagc catactttta aaaactgtca tagttgtgct taaaaaagat
      181 ggtgcatact gattcattat gcttggataa aaacaatgaa taatgtgtcc ctgaaggaaa
      241 agactataac aagtcttatc tggaatgcga tcgaaagatt tatggtacag ggagggcaat
      301 ttgtaataaa gattttaatt gcccgacaaa tctctcctga cgattatgga ttagtaggaa
      361 ttgttgctgt acttttagtt ttgtcggacg taattattaa tggggggttt tcgcaagctc
      421 taatacaaaa aaaagataga acatcactgg attactcaac tgtctt
//
LOCUS       DAPGUL010000377        23382 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.guided.070, whole genome shotgun sequence.
ACCESSION   DAPGUL010000377 DAPGUL010000000
VERSION     DAPGUL010000377.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23382)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23382)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23382
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.guided.070"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            413..886
                     /locus_tag="RHX21_004998"
     CDS             413..886
                     /locus_tag="RHX21_004998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001355915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrA1"
                     /protein_id="HDV1990015.1"
                     /translation="MKLSLMVAISKNGVIGNGPDIPWSAKGEQLLFKAITYNQWLLVG
                     RKTFESMGALPNRKYAVVTRSSFTSDNENVLIFPSIKDALTNLKKITDHVIVSGGGEI
                     YKSLIDQVDTLHISTIDIEPEGDVYFPEIPSNFRPVFTQDFASNINYSYQIWQKG"
     gene            981..1505
                     /gene="sat2"
                     /locus_tag="RHX21_004999"
     CDS             981..1505
                     /gene="sat2"
                     /locus_tag="RHX21_004999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat2"
                     /protein_id="HDV1990016.1"
                     /translation="MKISVIPEQVAETLDAENHFIVREVFDVHLSDQGFELSTRSVSP
                     YRKDYISDDDSDEDSACYGAFIDQELVGKIELNSTWNDLASIEHIVVSHTHRGKGVAH
                     SLIEFAKKWALSRQLLGIRLETQTNNVPACNLYAKCGFTLGGIDLFTYKTRPQVSNET
                     AMYWYWFSGAQDDA"
     gene            1563..2351
                     /gene="aadA1"
                     /locus_tag="RHX21_005000"
     CDS             1563..2351
                     /gene="aadA1"
                     /locus_tag="RHX21_005000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014325834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA1"
                     /protein_id="HDV1990017.1"
                     /translation="MREAVIAEVSTQLSEVVGVIERHLEPTLLAVHLYGSAVDGGLKP
                     HSDIDLLVTVTVRLDETTRRALINDLLETSASPGESEILRAVEVTIVVHDDIIPWRYP
                     AKRELQFGEWQRNDILAGIFEPATIDIDLAILLTKAREHSVALVGPAAEELFDPVPEQ
                     DLFEALNETLTLWNSPPDWAGDERNVVLTLSRIWYSAVTGKIAPKDVAADWAMERLPA
                     QYQPVILEARQAYLGQEDRLASRADQLEEFVHYVKGEITKVVGK"
     gene            2427..2924
                     /locus_tag="RHX21_005001"
     CDS             2427..2924
                     /locus_tag="RHX21_005001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001444089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1990018.1"
                     /translation="MRDLLKVVLSLVLAMASGQALADLPIVLVDEARLPYDYSPSNYD
                     ISPSNYDNSISNYDNSPSNYDNSESNYDNSSSNYDNSRNGNRRLIYSANGSRTFAGYY
                     VIANNGTTNFFSTSGKRMFYTPKGGRGVYGGKDGSFCGALVVINGQFSLALTDNGLKI
                     MYLSN"
     gene            2985..3356
                     /locus_tag="RHX21_005002"
     CDS             2985..3356
                     /locus_tag="RHX21_005002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1990019.1"
                     /translation="MSYEPPRDGYTNGYIVDVMYDNRPSKYPAVFRTYVRIPDYVELD
                     NAEELADAIIREVELKEAWLTRVLGNSADPDASVGKWDRRLAQCGGIDEMSSGVQATY
                     FSPNGQLVGLVAYIDAEWMDE"
     gene            3766..4143
                     /locus_tag="RHX21_005003"
     CDS             3766..4143
                     /locus_tag="RHX21_005003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001271300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDV1990020.1"
                     /translation="MSAAKALAYALCDKLESKKVDEVVRNLVSSGWNIREVAWEASSF
                     DHEMPYFDTGRDFDIGFPDTLSSKIEFLTANGSIVQARARLHFKQALIFAKASKHVAA
                     LKNSLDYYYGSSVIPPQNHGGYL"
     gene            4166..4318
                     /locus_tag="RHX21_005004"
                     /pseudo
     CDS             4166..4318
                     /locus_tag="RHX21_005004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011069623.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(4374..5990)
                     /locus_tag="RHX21_005005"
     CDS             complement(4374..5990)
                     /locus_tag="RHX21_005005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000251878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional antiterminator"
                     /protein_id="HDV1990021.1"
                     /translation="MVRLATFNDNVQVVHIGHLFRNSGHKEWRIFVWFNPMQERKWTR
                     FTHLPLLSRAKVVNSTTKQINKADRVIEFEASDLQRAKIIDFPNLSSFASVRNKDGAQ
                     SSFIYEAETPYSKTRYHIPQLELARSLFLINSYFCRSCLSSTALQQEFDVQYEVERDH
                     LEIRILPSSSFPKGALEQSAVVQLLVWLFSDQDVMDSYESIFRHYQQNREIKNGVESW
                     CFSFDPPPMQGWKLHVKGRSSNEDKDYLVEEIVGLEINAMLPSTTAISHASFQEKEAG
                     DGSTQHIAVSTESVVDDEHLQLDDEETANIDTDTRVIEAEPTWISFSRPSRIEKSRRA
                     RKSSQTILEKEEATTSENSNLVSTDEPHLGGVLAAADVGGKQDATNYNSIFANRFAAF
                     DELLSILKTKFACRVLFEETLVLPKVGRSRLHLCKDGSPRVIKAVGVQRNGSEFVLLE
                     VDASDGVKMLSTKVLSGVDSETWRNDFEKIRRGVVKSSLNWPNSLFDQLYGQDGHRGV
                     NHPKGLGELQVSREDMEGWAERVVREQFTH"
     gene            complement(5991..7517)
                     /locus_tag="RHX21_005006"
     CDS             complement(5991..7517)
                     /locus_tag="RHX21_005006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001243518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TniQ family protein"
                     /protein_id="HDV1990022.1"
                     /translation="MRNFPVPYSNELIYSTIARAGVYQGIVSPKQLLDEVYGNRKVVA
                     TLGLPSHLGVIARHLHQTGRYAVQQLIYEHTLFPLYAPFVGKERRDEAIRLMEYQAQG
                     AVHLMLGVAASRVKSDNRFRYCPDCVALQLNRYGEAFWQRDWYLPALPYCPKHGALVF
                     FDRAVDDHRHQFWALGHTELLSDYPKDSLSQLTALAAYIAPLLDAPRAQELSPSLEQW
                     TLFYQRLAQDLGLTKSKHIRHDLVAERVRQTFSDEALEKLDLKLAENKDTCWLKSIFR
                     KHRKAFSYLQHSIVWQALLPKLTVIEALQQASALTEHSITTRPVSQSVQPNSEDLSVK
                     HKDWQQLVHKYQGIKAARQSLEGGVLYAWLYRHDRDWLVHWNQQHQQERLAPAPRVDW
                     NQRDRIAVRQLLRIIKRLDSSLDHPRATSSWLLKQTPNGTSLAKNLQKLPLVALCLKR
                     YSESVEDYQIRRISQAFIKLKQEDVELRRWRLLRSATLSKERITEEAQRFLEMVYGEE
                     "
     gene            complement(7520..9187)
                     /locus_tag="RHX21_005007"
     CDS             complement(7520..9187)
                     /locus_tag="RHX21_005007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDV1990023.1"
                     /translation="MSATRIQAVYRDTGVEAYRDNPFIEALPPLQESVNSAASLKSSL
                     QLTSSDLQKSRVIRAHTICRIPDDYFQPLGTHLLLSERISVMIRGGYVGRNPKTGDLQ
                     KHLQNGYERVQTGELETFRFEEARSTAQSLLLIGCSGSGKTTSLHRILATYPQVIYHR
                     ELNVEQVVYLKIDCSHNGSLKEICLNFFRALDRALGSNYERRYGLKRHGIETMLALMS
                     QIANAHALGLLVIDEIQHLSRSRSGGSQEMLNFFVTMVNIIGVPVMLIGTPKAREIFE
                     ADLRSARRGAGFGAIFWDPIQQTQRGKPNQEWIAFTDNLWQLQLLQRKDALLSDEVRD
                     VWYELSQGVMDIVVKLFVLAQLRALALGNERITAGLLRQVYQDELKPVHPMLEALRSG
                     IPERIARYSDLVVPEIDKRLIQLQLDIAAIQEQTPEEKALQELDTEDQRHLYLMLKED
                     YDSSLLIPTIKKAFSQNPTMTRQKLLPLVLQWLMEGETVVSELEKPSKSKKVSAIKVV
                     KPSDWDSLPDTDLRYIYSQRQPEKTMHERLKGKGVIVDMASLFKQAG"
     gene            complement(9184..11292)
                     /locus_tag="RHX21_005008"
     CDS             complement(9184..11292)
                     /locus_tag="RHX21_005008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000267723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HDV1990024.1"
                     /translation="MWQINEVVLFDNDPYRILAIEDGQVVWMQISADKGVPQARAELL
                     LMQYLDEGRLVRTDDPYVHLDLEEPSVDSVSFQKREEDYRKILPIINSKDRFDPKVRS
                     ELVEHVVQEHKVTKATVYKLLRRYWQRGQTPNALIPDYKNSGAPGERRSATGTAKIGR
                     AREYGKGEGTKVTPEIERLFRLTIEKHLLNQKGTKTTVAYRRFVDLFAQYFPRIPQED
                     YPTLRQFRYFYDREYPKAQRLKSRVKAGVYKKDVRPLSSTATSQALGPGSRYEIDATI
                     ADIYLVDHHDRQKIIGRPTLYIVIDVFSRMITGFYIGFENPSYVVAMQAFVNACSDKT
                     AICAQHDIEISSSDWPCVGLPDVLLADRGELMSHQVEALVSSFNVRVESAPPRRGDAK
                     GIVESTFRTLQAEFKSFAPGIVEGSRIKSHGETDYRLDASLSVFEFTQIILRTILFRN
                     NHLVMDKYDRDADFPTDLPSIPVQLWQWGMQHRTGSLRAVEQEQLRVALLPRRKVSIS
                     SFGVNLWGLYYSGSEILREGWLQRSTDIARPQHLEAAYDPVLVDTIYLFPQVGSRVFW
                     RCNLTERSRQFKGLSFWEVWDIQAQEKHNKANAKQDELTKRRELEAFIQQTIQKANKL
                     TPSTTEPKSTRIKQIKTNKKEAVTSERKKRAEHLKPSSSGDEAKVIPFNAVEADDQED
                     YSLPTYVPELFQDPPEKDES"
     gene            complement(11279..12100)
                     /locus_tag="RHX21_005009"
     CDS             complement(11279..12100)
                     /locus_tag="RHX21_005009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heteromeric transposase endonuclease subunit
                     TnsA"
                     /protein_id="HDV1990025.1"
                     /translation="MAKANSSFSEVQIARRIKEGRGQGHGKDYIPWLTVQEVPSSGRS
                     HRIYSHKTGRVHHLLSDLELAVFLSLEWESSVLDIREQFPLLPSDTRQIAIDSGIKHP
                     VIRGVDQVMSTDFLVDCKDGPFEQFAIQVKPAAALQDERTLEKLELERRYWQQKQIPW
                     FIFTDKEINPVVKENIEWLYSVKTEEVSAELLAQLSPLAHILQEKGDENIINVCKQVD
                     IAYDLELGKTLSEIRALTANGFIKFNIYKSFRANKCADLCISQVVNMEELRYVAN"
     gene            complement(12260..14089)
                     /gene="glmS"
                     /locus_tag="RHX21_005010"
     CDS             complement(12260..14089)
                     /gene="glmS"
                     /locus_tag="RHX21_005010"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HDV1990026.1"
                     /translation="MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMT
                     RLRRLGKVQMLAQAAEEHPLHGGTGIAHTRWATHGEPSEANAHPHVSEHIVVVHNGII
                     ENHEPLREELKARGYTFVSETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTV
                     IMDSRHPDTLLAARSGSPLVIGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRR
                     SVNIFDKTGAEVKRQDIESNLQYDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQ
                     VDLSELGPNADELLSKVEHIQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYR
                     KSAVRRNSLMITLSQSGETADTLAGLRLSKELGYLGSLAICNVPGSSLVRESDLALMT
                     NAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLS
                     QDKRIEALAEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPL
                     ALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMP
                     HVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLAKSVTVE"
     gene            complement(14251..15621)
                     /gene="glmU"
                     /locus_tag="RHX21_005011"
     CDS             complement(14251..15621)
                     /gene="glmU"
                     /locus_tag="RHX21_005011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HDV1990027.1"
                     /translation="MLNNAMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAAN
                     ELGAAHVHLVYGHGGDLLKQALKDDNLNWVLQAEQLGTGHAMQQAAPFFADDEDILML
                     YGDVPLISVETLQRLRDAKPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATD
                     EQRQIQEINTGILIANGADMKRWLAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQ
                     RLSEVEGVNNRLQLSRLERVYQSEQAEKLLLAGVMLRDPARFDLRGTLTHGRDVEIDT
                     NVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAAACTIGPFARLRP
                     GAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANK
                     FKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKEGWR
                     RPVKKK"
     gene            complement(15972..16391)
                     /gene="atpC"
                     /locus_tag="RHX21_005012"
     CDS             complement(15972..16391)
                     /gene="atpC"
                     /locus_tag="RHX21_005012"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001251972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HDV1990028.1"
                     /translation="MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLT
                     AIKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKA
                     EEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM"
     gene            complement(16412..17794)
                     /gene="atpD"
                     /locus_tag="RHX21_005013"
     CDS             complement(16412..17794)
                     /gene="atpD"
                     /locus_tag="RHX21_005013"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017800291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HDV1990029.1"
                     /translation="MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQ
                     QQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEI
                     GEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNM
                     MELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRL
                     RVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEM
                     GVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPA
                     VDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVA
                     RARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSI
                     EEAVEKAKKL"
     gene            complement(17821..18684)
                     /gene="atpG"
                     /locus_tag="RHX21_005014"
     CDS             complement(17821..18684)
                     /gene="atpG"
                     /locus_tag="RHX21_005014"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HDV1990030.1"
                     /translation="MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRP
                     YAETMRKVIGHLAHGNLEYKHPYLEDRDVKRVGYLVVSTDRGLCGGLNINLFKKLLAE
                     MKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAY
                     DEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDT
                     LLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQE
                     LTEIVSGAAAV"
     gene            complement(18735..20276)
                     /gene="atpA"
                     /locus_tag="RHX21_005015"
     CDS             complement(18735..20276)
                     /gene="atpA"
                     /locus_tag="RHX21_005015"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HDV1990031.1"
                     /translation="MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGL
                     ADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRG
                     LLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIG
                     RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGAL
                     ANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLL
                     LRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQA
                     GDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGG
                     IRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFA
                     AERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFK
                     ATQSW"
     gene            complement(20289..20822)
                     /gene="atpH"
                     /locus_tag="RHX21_005016"
     CDS             complement(20289..20822)
                     /gene="atpH"
                     /locus_tag="RHX21_005016"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HDV1990032.1"
                     /translation="MSEFITVARPYAKAAFDFAVEHQSVERWQDMLAFAAEVTKNEQM
                     AELLSGALAPETLAESFIAVCGEQLDENGQNLIRVMAENGRLNALPDVLEQFIHLRAV
                     SEATAEVDVISAAALSEQQLAKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRAGDMVI
                     DGSVRGRLERLADVLQS"
     gene            complement(20837..21307)
                     /gene="atpF"
                     /locus_tag="RHX21_005017"
     CDS             complement(20837..21307)
                     /gene="atpF"
                     /locus_tag="RHX21_005017"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HDV1990033.1"
                     /translation="MNLNATILGQAIAFVLFVLFCMKYVWPPLMAAIEKRQKEIADGL
                     ASAERAHKDLDLAKASATDQLKKAKAEAQVIIEQANKRRSQILDEAKAEAEQERTKIV
                     AQAQAEIEAERKRAREELRKQVAILAVAGAEKIIERSVDEAANSDIVDKLVAEL"
     gene            complement(21369..21608)
                     /gene="atpE"
                     /locus_tag="RHX21_005018"
     CDS             complement(21369..21608)
                     /gene="atpE"
                     /locus_tag="RHX21_005018"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HDV1990034.1"
                     /translation="MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPD
                     LIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA"
     gene            complement(21655..22470)
                     /gene="atpB"
                     /locus_tag="RHX21_005019"
     CDS             complement(21655..22470)
                     /gene="atpB"
                     /locus_tag="RHX21_005019"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HDV1990035.1"
                     /translation="MASENMTPQDYIGHHLNNLQLDLRTFSLVDPQNPPATFWTINID
                     SMFFSVVLGLLFLVLFRSVAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIA
                     PLALTIFVWVFLMNLMDLLPIDLLPYIAEHVLGLPALRVVPSADVNVTLSMALGVFIL
                     ILFYSIKMKGIGGFTKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAG
                     ELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH"
     gene            complement(22479..22859)
                     /gene="atpI"
                     /locus_tag="RHX21_005020"
     CDS             complement(22479..22859)
                     /gene="atpI"
                     /locus_tag="RHX21_005020"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418195.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit I"
                     /protein_id="HDV1990036.1"
                     /translation="MSVSLVSRNVARKLLLVQLLVVIASGLLFSLKDPFWGVSAISGG
                     LAVFLPNVLFMIFAWRHQAHTPAKGRVAWTFAFGEAFKVLAMLVLLVVALAVLKAVFL
                     PLIVTWVLVLVVQILAPAVINNKG"
BASE COUNT         6032 a         5964 c         5298 g         6088 t
ORIGIN      
        1 gtaagttttt tcagttttca gcgcataacc tttttgtcgc atatccgtgc gtatagaatt
       61 taaaaatgga ctgttagaca taaaacgctc cttgtcttgc aactgtctgc ctatacagcc
      121 tattctagct gggatttaaa aaagtgcctg ttttttacgc ctagagatgc ttgtttaccg
      181 gtagagtttt aatttaatgc taaataaatt aaaatgttat gagttctttg ggtgagataa
      241 tgtgcatcgt gcaagcagga tagacggcat gcacgatttg taataacaga gtgtcttgta
      301 tttttaaaga aagtctattt aatacaagtg attatattaa ttaacggtaa gcatcagcgg
      361 gtgacaaaac gagcatgctt actaataaaa tgttaacctc tgaggaagaa ttgtgaaact
      421 atcactaatg gtagctatat cgaagaatgg agttatcggg aatggccctg atattccatg
      481 gagtgccaaa ggtgaacagc tcctgtttaa agctattacc tataaccaat ggctgttggt
      541 tggacgcaag acttttgaat caatgggagc attacccaac cgaaagtatg cggtcgtaac
      601 acgttcaagt tttacatctg acaatgagaa cgtattgatc tttccatcaa ttaaagatgc
      661 tttaaccaac ctaaagaaaa taacggatca tgtcattgtt tcaggtggtg gggagatata
      721 caaaagcctg atcgatcaag tagatacact acatatatct acaatagaca tcgagccgga
      781 aggtgatgtt tactttcctg aaatccccag caattttagg ccagttttta cccaagactt
      841 cgcctctaac ataaattata gttaccaaat ctggcaaaag ggttaacaag tggcagcaac
      901 ggattcgcaa acctgtcacg ccttttgtac caaaagccgc gccaggtttg cgatccgctg
      961 tgccaggcgt taggcgtcat atgaagattt cggtgatccc tgagcaggtg gcggaaacat
     1021 tggatgctga gaaccatttc attgttcgtg aagtgttcga tgtgcaccta tccgaccaag
     1081 gctttgaact atctaccaga agtgtgagcc cctaccggaa ggattacatc tcggatgatg
     1141 actctgatga agactctgct tgctatggcg cattcatcga ccaagagctt gtcgggaaga
     1201 ttgaactcaa ctcaacatgg aacgatctag cctctatcga acacattgtt gtgtcgcaca
     1261 cgcaccgagg caaaggagtc gcgcacagtc tcatcgaatt tgcgaaaaag tgggcactaa
     1321 gcagacagct ccttggcata cgattagaga cacaaacgaa caatgtacct gcctgcaatt
     1381 tgtacgcaaa atgtggcttt actctcggcg gcattgacct gttcacgtat aaaactagac
     1441 ctcaagtctc gaacgaaaca gcgatgtact ggtactggtt ctcgggagca caggatgacg
     1501 cctaacaatt cattcaagcc gacaccgctt cgcggcgcgg cttaattcag gagttaaaca
     1561 tcatgaggga agcggtgatc gccgaagtat cgactcaact atcagaggta gttggcgtca
     1621 tcgagcgcca tctcgaaccg acgttgctgg ccgtacattt gtacggctcc gcagtggatg
     1681 gcggcctgaa gccacacagt gatattgatt tgctggttac ggtgaccgta aggcttgatg
     1741 aaacaacgcg gcgagctttg atcaacgacc ttttggaaac ttcggcttcc cctggagaga
     1801 gcgagattct ccgcgctgta gaagtcacca ttgttgtgca cgacgacatc attccgtggc
     1861 gttatccagc taagcgcgaa ctgcaatttg gagaatggca gcgcaatgac attcttgcag
     1921 gtatcttcga gccagccacg atcgacattg atctggctat cttgctgaca aaagcaagag
     1981 aacatagcgt tgccttggta ggtccagcgg cggaggaact ctttgatccg gttcctgaac
     2041 aggatctatt tgaggcgcta aatgaaacct taacgctatg gaactcgccg cccgactggg
     2101 ctggcgatga gcgaaatgta gtgcttacgt tgtcccgcat ttggtacagc gcagtaaccg
     2161 gcaaaatcgc gccgaaggat gtcgctgccg actgggcaat ggagcgcctg ccggcccagt
     2221 atcagcccgt catacttgaa gctaggcagg cttatcttgg acaagaagat cgcttggcct
     2281 cgcgcgcaga tcagttggaa gaatttgttc actacgtgaa aggcgagatc accaaggtag
     2341 tcggcaaata atgtctaaca attcgttcaa gccgacgccg cttcgcggcg cggcttaact
     2401 caagcgttag agagctgggg aagactatgc gcgatctgtt gaaggtggtt ctaagcctcg
     2461 tacttgcgat ggcatcgggg caggcacttg ctgacctgcc aattgtttta gtggatgaag
     2521 ctcgtcttcc ctatgactac tccccatcca actacgacat ttctccaagc aactacgaca
     2581 actccataag caattacgac aatagtccat caaattacga caactctgag agcaactacg
     2641 ataatagttc atccaattac gacaatagtc gcaacggaaa tcgtaggctt atatatagcg
     2701 caaatgggtc tcgcactttc gccggctact acgtcattgc caacaatggg acaacgaact
     2761 tcttttccac atctggcaaa aggatgttct acaccccaaa aggggggcgc ggcgtctatg
     2821 gcggcaaaga tgggagcttc tgcggggcat tggtcgtcat aaatggccaa ttttcgcttg
     2881 ccctgacaga taacggcctg aagatcatgt atctaagcaa ctagcctgct ctctaataaa
     2941 atgttaggcc tcaacatcta gtcgcaagct gaggggaacc actagtgtca tacgaacctc
     3001 caagagacgg ttacacaaac gggtacattg ttgatgtcat gtatgacaat cgcccaagta
     3061 agtatccagc tgtgttcaga acgtacgtcc gaattccaga ctatgtcgaa ctagataacg
     3121 cggaggagct ggccgacgca atcattcgag aggttgagtt aaaggaggca tggctcacaa
     3181 gggtcttggg gaactcagcc gatcctgacg cttctgtggg caagtgggac cggcgcctag
     3241 cgcagtgcgg tggtattgat gagatgtcaa gtggggtgca ggcaacatac ttcagtccaa
     3301 acggtcagct ggtcggctta gtggcataca ttgatgccga atggatggat gaatagctct
     3361 gacgttacga ttcaggtgag acaaccagat gggcattgcg tacaagctca gttgccaccg
     3421 atgtggctac gagtctgatc ttctttacct aggccaaggt atggcgatgc ttcctgagca
     3481 aatagtcgga acgtgcacat gctgcgacaa tctaacgacg atttctataa atgaaagcta
     3541 cggagtatgc tcactttgtg gggctaagga tcgtgtgata tttacaagct atcagcatga
     3601 ggcaaggcca agaaatccct gctatctaga gagaagtttc aaatatcaat gcccaagatg
     3661 ccatgccttc agtatggagc ctccggatct accggagatg ctttgggact aatgctccgc
     3721 tttgcctcgg gtatccgttc gacctatgtt taagaggaaa cgcacgtgtc tgccgccaaa
     3781 gctcttgcct atgcactttg tgacaagttg gaaagcaaaa aagttgatga agtcgtacga
     3841 aatcttgttt ctagcggctg gaatattagg gaagtggcct gggaagcttc gtcctttgat
     3901 catgaaatgc cctactttga cacggggcgg gacttcgata ttggatttcc tgacacgctg
     3961 tcatccaaga ttgagttttt gaccgcgaat ggatcaatcg tccaagcacg tgctcgcctg
     4021 cacttcaagc aggctctaat ttttgccaag gcgtccaaac atgtcgccgc gctcaagaac
     4081 tcattggatt actactatgg atcgtctgta atcccccctc aaaaccacgg aggctatttg
     4141 tagaaaattc cattaatatg aactcaaggt gttccctacg gacgaatcag cgatgaaggt
     4201 ggtgtacctg gctatccagg cggcgaccaa gaaatggacg atgccgatcc gcaactggaa
     4261 gccggccatg aaccgtttta tgatcgaatt tggtgaccgt ttaaatggcc acctttaact
     4321 gaccggcaaa agcacttaca caaaagggtt tacaggctct ttcagtcatt cctttaatgc
     4381 gtaaattgct ctctaaccac tctctcagcc cacccttcca tatcctctct cgatacttgc
     4441 agctccccca acccctttgg atgattcacc cctctatgcc cgtcttgtcc atataattga
     4501 tcaaacaaac tatttggcca attcaatgag ctcttcacca ctccacgccg tatcttttca
     4561 aaatcattcc gccatgtttc gctatcaacg ccactcaaca ctttggtaga aagcattttc
     4621 accccatccg atgcatccac ctctagcaat acaaattcac tgccattacg ttgcacccca
     4681 acggctttaa tcactcttgg tgagccatct ttacacagat gtaatcggct acgcccaact
     4741 tttggcaaaa ccaaggtttc ttcaaaaagc acccgacatg caaatttagt ttttagaatt
     4801 gaaagtagct catcaaaagc agcaaatcga ttagcaaaaa tagagttgta attggttgca
     4861 tcctgcttcc cacccacatc tgccgctgct aggacaccac ctaagtgtgg ctcatcagta
     4921 ctaaccaaat tactattttc acttgttgtt gcttcttctt tttctaaaat agtttggcta
     4981 ctttttcttg ccctgcgaga tttttcaatt cgactaggtc tactaaaact tatccatgtc
     5041 ggctcagcct ctatgactcg tgtgtctgtg tctatattgg ctgtttcctc atcgtccaac
     5101 tgtagatgct catcatcaac aactgactct gttgaaaccg ctatgtgctg cgtactacca
     5161 tcacctgcct ccttttcctg aaaagaggca tggctaatag ctgttgtgct aggaagcata
     5221 gcgttgattt ctaaacctac tatttcctca actaaataat ccttatcctc gttagaagaa
     5281 cgtcctttta catgtaattt ccaaccctgc atgggcggag ggtcaaagct aaagcaccag
     5341 ctttcaacgc cgttcttaat ttctctattt tgttgatagt gcctaaaaat actttcatac
     5401 gaatccataa catcttgatc cgaaaacaac caaaccaaaa gctgcactac ggccgactgc
     5461 tctaacgccc ctttaggaaa cgatgaactg ggtaagatcc ttatctctaa atgatctcgc
     5521 tcaacctcat actgaacgtc gaactcttgc tgtaaagcgg tactgctcaa acagcttcga
     5581 cagaaatagg agttaattaa aaataatgac cgagctagct ctaactgtgg gatgtgataa
     5641 cgagtcttgc tatatggtgt ttcagcttcg taaataaatg aactctgcgc tccatccttg
     5701 ttgcgtacgg aagcaaagga cgagagatta ggaaaatcga ttattttggc tcgttgaaga
     5761 tccgatgctt caaactcaat cacacgatcc gccttattta tttgctttgt tgtactgtta
     5821 accaccttag ctcgacttaa taaaggcaaa tgagtaaatc gagtccattt ccgttcttgc
     5881 attggattaa accaaacaaa aatacgccac tccttatgac ccgagttacg gaataaatga
     5941 ccaatatgta caacctgcac attgtcatta aatgtagcta gcctaaccac tcactcttcc
     6001 ccataaacca tttccaagaa tctttgtgct tcctcagtta tccgctcttt agataacgtt
     6061 gcacttctta ataatcgcca gcgcctaagc tcaacatctt cctgtttaag cttaataaaa
     6121 gcttggctaa tccgtctaat ttgataatct tccacactct ctgagtaacg ctttaagcaa
     6181 agcgctacca aaggcagttt ctgtagattt tttgcaagag aggttccgtt aggagtttgc
     6241 tttaacagcc agctcgatgt cgctcttggg tgatcaaggc tactatctag acgctttatg
     6301 attcttaata gttgtcgtac agcaattcga tctctttggt tccaatcaac tctaggggcg
     6361 ggtgccagac gctcttgttg atgctgttga ttccagtgaa ctagccaatc cctgtcatgt
     6421 cggtaaagcc aagcgtatag caccccaccc tctaaagact gtcttgccgc cttaattcct
     6481 tggtatttat gcactagttg ctgccagtct ttatgcttaa cagataaatc ttcagagtta
     6541 ggttgcacag actggctaac aggtcttgtc gttatagagt gctcagtaag agcacttgcc
     6601 tgctgtagcg cttctataac cgttagtttt ggcaataagg cttgccacac aatactatgc
     6661 tgtaaataac taaaggcttt tctatgctta cggaatatac ttttcagcca acacgtgtcc
     6721 ttgttctctg ccaactttaa atccagtttc tctagtgcct catcactaaa agtctgcctc
     6781 actctctccg ccaccaagtc atgacgaatg tgcttgcttt tggttagccc tagatcctgc
     6841 gctaagcgct gataaaacag cgtccactgc tcaaggcttg gggaaagctc ttgcgctcgt
     6901 ggagcatcta acagaggggc tatataagca gctagtgctg ttaattgaga tagggagtct
     6961 ttggggtagt ctgaaagcag ctcagtatga cccaaagccc aaaattgatg tcggtgatca
     7021 tctacagctc tatcaaagaa gactaaagca ccgtgttttg gacaatatgg caaagcgggc
     7081 aaataccaat ctcgttgcca aaaggcttcc ccatacctat ttagctgaag agcaacgcaa
     7141 tcagggcagt atctaaagcg gttatcgctc ttaactctag aagcagcgac tcctagcatt
     7201 aaatgcaccg caccttgcgc ttggtactcc attaaccgaa tagcttcgtc tcggcgctcc
     7261 ttgcctacaa acggagcata taaagggaat aaggtatgct cataaataag ctgctgaaca
     7321 gcgtaacgtc ctgtttgatg tagatgtctt gctatcacac ctaaatgcga gggcagacct
     7381 aaggtagcga ccaccttgcg gttgccatac acctcatcca acagctgctt aggactaaca
     7441 atcccttgat aaacgcctgc ccgtgcaata gtgctataaa tcagctcatt cgagtacgga
     7501 acaggaaagt ttctcatggc taacctgctt gtttaaataa gctcgccata tccactatta
     7561 cccctttccc ttttaaccgt tcatgcatgg ttttttcagg ttggcgttgt gaatagatat
     7621 aacgtaaatc cgtatcaggc aagctatccc agtcgctggg cttgactacc tttatagccg
     7681 aaaccttttt actcttggag ggcttttcta gttctgacac taccgtttcg ccttccatca
     7741 accactgcaa aacaagaggc agtaactttt gtcttgtcat cgttggattc tggctaaacg
     7801 cttttttaat agtgggaatt aacaggcttg aatcgtaatc ctctttcagc atcagatata
     7861 aatgacgctg atcttcggta tctaactctt gaagggcttt ttcttctggt gtttgttctt
     7921 gtatcgctgc gatatctagc tgaagttgga ttaaccgttt atcaatctcg ggaacgacta
     7981 gatcagaata acgagcaatg cgttctggga tacccgagcg taatgcctct agcatggggt
     8041 gcacaggctt taactcatct tgatacactt gccgcaataa accagcggta atacgctcat
     8101 tgcctaaagc tagcgcacgg agctgagcga gtacaaaaag ttttactaca atgtccatca
     8161 ctccttggct tagctcatac cacacatcac ggacctcatc cgataacagc gcatctttgc
     8221 gttgtaaaag ctgtaattgc caaagattat ccgtaaaagc gatccactct tgattgggct
     8281 ttccacgttg cgtttgttgt ataggatccc agaatatagc tccaaaccct gcccctctac
     8341 gtgcagaccg caaatcagcc tcaaaaatct ctcgtgcttt aggggtacca atcaacatca
     8401 ctggtacgcc aataatattc accatcgtca caaaaaagtt cagcatctct tgagatccac
     8461 ccgaacgaga gcggcttaaa tgctgaattt catcaataac caacaaccct aaagcatgtg
     8521 cattggctat ttgcgacatc aaagccaaca tggtttctat accatgacgt tttaagccat
     8581 aacgacgctc atagttcgag cccaaggctc gatccaacgc tctgaaaaaa ttcaagcaga
     8641 tttcttttag cgaaccatta tgcgagcagt ctattttcaa atacaccacc tgctctacat
     8701 tgagttcacg atggtaaatc acctgaggat acgtggctag aatacgatga agagaggtcg
     8761 tcttcccact accagaacaa ccaattaaca ataagctttg tgccgtagat cgtgcctcct
     8821 caaagcgaaa tgtctccaac tctcccgttt gaacacgctc ataaccattt tgtaaatgct
     8881 tttgtaaatc tcctgtttta ggatttctgc ctacgtagcc acctcgaatc atgaccgaaa
     8941 tacgctcact tagtagcaaa tgcgtaccta atggctgaaa atagtcatct ggaatacgac
     9001 aaatggtatg agctctgata acacgggact tttgcaagtc agaggaagta agctgtaaag
     9061 aggatttcag tgatgcagca ctattcactg actcttgtaa tggtggtaag gcctcgataa
     9121 aaggattatc acgataagcc tctacccccg tatcacgata aactgcttga atccgggtag
     9181 cactcatgac tcatcctttt ctggtggatc ctgaaataat tcaggcacgt atgtgggtag
     9241 gctgtaatct tcttgatcat ccgcttccac tgcgttgaaa ggaataactt tagcctcatc
     9301 acctgaagag cttggcttca aatgctccgc acgtttttta cgctccgagg tcacggcttc
     9361 ttttttatta gttttaatct gcttaatgcg tgttgatttg ggctcagtag tactgggcgt
     9421 taacttattc gctttctgaa tggtttgctg aataaacgcc tcaagctccc tgcgtttagt
     9481 taactcatcc tgcttcgcat tggctttatt gtgtttttct tgtgcttgta tatcccaaac
     9541 ctcccaaaat gagagacctt taaactgccg actacgttcc gtcagattac agcgccaaaa
     9601 tacacggctg ccaacttgcg gaaacaaata aatcgtatca accagcactg ggtcataagc
     9661 cgcttctaaa tgttgaggtc tagctatatc agtgctccgc tgcaaccaac cctcacgcag
     9721 aatctctgac cccgagtaat acaaacccca caaattaacg ccaaatgaag aaatagagac
     9781 ctttcggcga ggcagtaacg ctactcgcaa ctgctcttgc tccacagccc ttaaactacc
     9841 tgtacgatgc tgcatacccc attgccatag ctggacagga atagacggta aatctgtagg
     9901 aaaatcagca tctcgatcgt atttatccat caccagatgg ttatttctga ataagatcgt
     9961 acgcaaaata atttgtgtga actcaaatac cgacagagat gcatctaacc tatagtctgt
    10021 ttcaccatgg cttttgatcc gactgccctc tacaatgcca ggtgcaaagg acttaaactc
    10081 ggcttgtagt gttctaaaag tgctttccac tatgccttta gcatcgccac gtctaggtgg
    10141 agcactttcc actcgcacat taaaactaga aactaaggct tcgacctgat gactcattaa
    10201 ttcgccacgg tccgctagca acacatctgg caaacctaca cacggccagt ctgagctact
    10261 aatctcaata tcatgctggg cacaaatggc cgttttgtca gagcaagcat ttacaaaagc
    10321 ctgcatcgcc accacataag acggattttc aaagccgata taaaagcccg tgatcatccg
    10381 actaaacaca tcaatcacaa tgtaaagcgt tggtcttcct atgatttttt ggcgatcatg
    10441 atgatccact aaataaatat cagcaatcgt ggcatcaatc tcataacgac tcccagggcc
    10501 taacgcctga gaagtggctg tactacttaa gggtcgtacg tcttttttat atacccctgc
    10561 tttaactcta gactttaagc gctgagcttt agggtattct cgatcataaa aataacgaaa
    10621 ctgacgtagt gttgggtaat cctcttgggg aatgcgagga aaatactgag caaacaagtc
    10681 cacaaatcgt ctataggcaa cggtggtctt tgtacctttt tgatttaaca ggtgcttttc
    10741 tatggtcaac ctaaaaaggc gttcaatctc gggcgttacc ttggttcctt cacccttacc
    10801 atattctctg gctcggccaa tctttgctgt tcctgtcgct gaacgtcttt cccctggtgc
    10861 accgctgttt ttgtagtcag gaattaatgc attaggcgtt tgaccacgct gccagtaacg
    10921 gcgtaacaac ttataaactg tagccttagt aaccttatgt tcttggacca catgctcaac
    10981 gagttcgctt ctgactttag ggtcgaaacg atccttacta ttaataatag gaagaatttt
    11041 tcgataatcc tcctcgcgct tctggaagct gacagaatct acagacggct cttctaaatc
    11101 aagatgtaca taagggtcat cagttctaac taagcggcct tcatctaaat actgcattag
    11161 caacaactca gccctagctt gtggaactcc tttatcagcg cttatttgca tccagacaac
    11221 ttggccatcc tctatagcca aaatgcgata cggatcatta tcaaatagca caacctcatt
    11281 aatttgccac atagcgcaac tcctccatat tcactacttg gctaatacag agatctgcac
    11341 acttatttgc cctgaaagac ttataaatat tgaacttaat aaaaccattt gcggttaagg
    11401 ctcgtatctc actcaatgtt ttgcctaact ccaaatcata agcaatatca acctgcttac
    11461 agacattgat aatgttttca tctccttttt cttgcaggat atgggccaat ggggatagtt
    11521 gtgctaaaag ctccgcagaa acttcttctg ttttcactga ataaagccat tcaatatttt
    11581 cttttactac gggatttatt tctttatcag taaaaatgaa ccaaggaatt tgcttttgct
    11641 gccaatagcg acgctctagt tctagttttt ctaaggtacg ctcgtcttgt aaggctgctg
    11701 caggtttgac ttgaatagca aactgctcaa aaggaccatc tttgcagtcc actaaaaaat
    11761 cagtagacat aacctgatct acaccacgaa taacaggatg cttaatacca ctatctattg
    11821 caatctgcct ggtatcacta ggtaataagg ggaactgctc gcgtatatct agcacgctgc
    11881 tctcccactc aagactgaga aaaacagcaa gctctaagtc agatagcaaa tgatggactc
    11941 gtcccgtctt atgagaataa atacggtggg aacgacctga agaaggaact tcttgtactg
    12001 ttagccatgg aatatagtct ttaccatgcc cttggccacg cccctcttta atacgacggg
    12061 caatttgcac ttcagaaaat gaagagtttg ctttagccat aacaaaagtc cagtatgctt
    12121 tttcacagca taactggact gatttcagtt tacaactatt ctgtctagtt taagacttta
    12181 ttgtcatagt ttagatctat tttgttcagt ttaagacttt attgtccgcc cacacccgct
    12241 tacgcagggc atccatttat tactcaaccg taaccgattt tgccaggtta cgcggctggt
    12301 caacgtcggt acctttgatc agcgcgacgt gataagccag tagctgcagc ggaacggtgt
    12361 agaagattgg tgcaatcacc tcttccacat gcggcatctc gatgatgtgc atgttatcgc
    12421 tacttacaaa acccgcatcc tgatcggcga agacatacaa ctgaccgcca cgcgcgcgaa
    12481 cttcttcaat gttggatttt agtttttcca gcaattcgtt gttcggtgca acgacgataa
    12541 ccggcatatc ggcatcaatc agcgccagcg gaccgtgttt cagttcacct gcagcgtagg
    12601 cttcagcgtg aatgtaagag atctctttca gcttcaatgc gccttccagc gcgattgggt
    12661 actgatcgcc acggcccagg aacagcgcgt gatgtttgtc agagaaatct tctgccagag
    12721 cttcaatgcg tttgtcctga gacagcatct gctcaatacg gctcggcagc gcctgcagac
    12781 catgcacaat gtcatgttca atggaggcat ccagaccttt caggcgagac agcttcgcca
    12841 ccagcatcaa cagcacagtt aactgagtgg tgaatgcttt agtggatgcc acgccgattt
    12901 ctgtaccggc gttggtcatc agcgccagat cggattcgcg caccagagaa gaacccggaa
    12961 cgttacagat tgccagcgaa ccaaggtaac ccagctcttt cgacagacgc aggcccgcca
    13021 gggtatccgc ggtttcgcca gactgtgaca aggtgatcat caggctgtta cgacgcacgg
    13081 cagatttacg atagcggaat tcagaggcga tttcgacgtc gcacggaata cctgccagcg
    13141 attcaaacca gtagcgggaa accataccgg agttataaga agtaccacag gcgaggatct
    13201 gaatatgctc aaccttcgac agcagttcgt cggcgttcgg tcccagctcg cttaaatcaa
    13261 cctgaccgtg gctgatgcgc ccggtaaggg tgttttttat cgcgttcggc tgttcgtaga
    13321 tctctttctg catgtagtga cggtaaatac ctttatcgcc cgcgtcatat tgcagattgg
    13381 attcgatatc ctgacgtttt acttccgcgc cagttttatc gaagatgttt accgaacggc
    13441 gagtaatttc cgcaatatcg ccctcttcaa ggaagataaa gcgacgggtc accggcaaca
    13501 gcgccagctg gtcagaagcg ataaagtttt cgcccatacc caggccaatc accagcggac
    13561 taccagaacg tgccgccagc agggtatccg ggtgacggga gtccatgatc actgtaccgt
    13621 acgcaccgcg cagctgcggg atagcacgca gaacagcctc acgcagagtc ccgccttgtt
    13681 tcagctccca gttcaccaga tgggcaatta cttcggtgtc tgtttcagaa acgaaggtat
    13741 agccacgcgc ttttaactct tcacgcagcg gttcatggtt ttcgatgatg ccgttatgca
    13801 ccaccacaat gtgttcagaa acatgcggat gcgcgttagc ttctgaaggt tcaccgtggg
    13861 tcgcccagcg agtgtgagca ataccggtgc cgccatgcag aggatgttct tccgctgcct
    13921 gagccagcat ctggacttta ccgaggcgac gcaggcgggt catatgacct tccgcatcaa
    13981 caacggccag accggcagag tcatatccgc ggtattccag acgacgtaaa ccttcaagaa
    14041 ggatttctgc tacatcacgt tgcgcgatcg cgccaacaat tccacacata gtttttgatt
    14101 ccgatttata tcgttgtcgg tcaacctgta tgcccgtttt ttcgggcgcc ccgagccttg
    14161 tagagagtgg ggttattttt atagttactg cttgtgggag ggagattatg ttatctcctc
    14221 atcccagatg accggattac ccggccagaa ttactttttc tttaccggac gacgccagcc
    14281 ttctttctga gtctgcggca cacggctgat agctaatgca ttttcgccga cattacgcgt
    14341 cacagttgta cccgcagcaa tggtcgcgcc tttgcctact gttaccgggg ccaccagctg
    14401 agtgtcggaa ccgacaaaca catcgtcgcc gataatggtc ttaaatttat tcgcaccatc
    14461 gtagttgcag gtaattgttc ccgcgccgat gttaacgtta tcgccaattt ccgcatcgcc
    14521 caggtaagtc agatgcccgg ctttcgagcc tttacccaga cgcgcttttt tcatctcaac
    14581 gaagttacca acgtgtgcac cttccagcaa ctcagcacca ggacgcagac gggcaaacgg
    14641 gccaatagta caggccgctg ccagattcgc gtcttccaca acggtatacg gactgatttc
    14701 gcaatcatcg ccaatcacgc tgtttttaat cacgcaaccg gtgccgattt tcacgcgatg
    14761 accgagagtc acgttgccct cgatgataac gttagtatca atttcaacat cgcgcccgtg
    14821 agtaagcgta ccgcgcagat caaaacgcgc cggatcgcgc agcataacgc ctgctaacag
    14881 cagtttttca gcctgttcgg actggtaaac gcgctccaga cgggagagtt gcaggcggtt
    14941 attcacacct tctacttcgc ttaaacgttg cggatgaacg gcgacgattt cacgcccttc
    15001 ctgatacgcc agcgcaataa tgtcggtgat gtagtattcg ccctgagcat tattgttggt
    15061 cagcttcgcc agccagcgtt tcatatctgc gccgttagcg atcagaatgc cggtgttgat
    15121 ctcctgaatc tgacgctgct cgtcggtggc atctttgtgc tcaacaatgc cggtaacttt
    15181 gccattttca cgggtgatac gtccataacc ggtcggatca tccagtttca ccgtcagcag
    15241 accaatgcca ccctgcggtt tagcatcacg caggcgctgg agtgtttcga cagagatcag
    15301 cggcacgtcg ccgtagagca ttaaaatgtc ttcatcatcg gcaaagaaag gtgcggcctg
    15361 ctgcattgca tgacccgtac ccagctgctc tgcctgaagc acccagttaa ggttgtcgtc
    15421 tttcagcgcc tgtttaagca gatcgccgcc gtgaccgtac accaggtgaa cgtgcgctgc
    15481 gcctaattca ttcgcagcat caatgacatg ctgaaccatc gctttcccgg caagggtatg
    15541 cagcactttc ggaagatcgg aatacatgcg cgtgcctttg cctgcggcaa ggatcactac
    15601 gctcatagca ttattcaaca tacgcgtcct gactgtaatt tgagaacgaa tttaaaccgc
    15661 ttcaccttga aaaaactaca tttttttcat cgtgaaatgg acagaggata aattgttcaa
    15721 taacggatta tccccgctga cgaaagtgcc attttcgacc atcgtcacgc cttttgtctg
    15781 cagaaaatta aggcagtacc ttcatttaag cgtcaggtgg atgtttttgc tcttatttcg
    15841 atcaatgaat aaacgggaaa acaggggtgt tttatatcag caggatctat gtgaacgctc
    15901 ttcaggacgg atcacgcgta aaaaaaagcc agcctgtttc cagactggct tttgtgcttt
    15961 tcaagccggt gttacatcgc ttttttggtc aactcgataa cgcgcagctg cgcgatcgct
    16021 ttggccagtt ccgcagacgc ctgagcgtaa tctacgtcgc cgtgagagct gctaatgtgc
    16081 tcttcagcct tacgtttcgc ttccatggct cgcgcttcgt cgagatcctg gccgcgaatt
    16141 gcggtgtcgg ccagaacggt cacgttgcca ggctgcactt caagaatgcc gccagacaga
    16201 tagataaact cttcgtgacc gtgctgtttc acgatgcgaa tcataccagg cttaatggcg
    16261 gtgagcagcg gtgcgtggcc agggtagatc cccagttcac cttcgctacc cgttacctgg
    16321 attttctcga ccagaccaga gaacatttgt tgctctgcgc tgacgacgtc caggtggtaa
    16381 gtcattgcca tatcaccctc cgattaaggc gttaaagttt tttggctttt tccacagctt
    16441 cttcgatgga accgaccatg tagaacgcct gctccggcag gtgatcgtat tcgccttcca
    16501 tgatgccttt aaagccacgg atggtgtctt tcagggagac gtatttaccc ggagaaccgg
    16561 tgaatacttc tgccacgaag aacggctggg acaggaagcg ctggatctta cgagcacgcg
    16621 ctaccaccag tttgtcttct tcagacagtt catccatacc caggatggcg atgatgtctt
    16681 tcagttcctg ataacgttgc aggatggact gaacgccacg cgcggtgtcg tagtgttcct
    16741 gaccaaccac cagcgggtcc agctgacggc tggtggagtc cagcgggtca acggccgggt
    16801 agatacccag agacgcgatc tgacggctca gtaccacggt tgcgtcaagg tgcgcaaagg
    16861 tggttgccgg agacgggtca gtcaagtcat ccgcaggtac gtatactgcc tgtacggagg
    16921 tgatagaacc agttttggtg gaggtgatac gttcctgcag aacgcccatc tcttccgcca
    16981 gggtcggctg ataacctacc gctgaaggca tacggcccag cagtgcggat acttccgtac
    17041 cggccagggt gtaacgatag atgttgtcaa cgaacagcag aacgtcacga ccttcgtcac
    17101 ggaatttctc agccatggtc agaccggtca gagcaacgcg cagacggttt cccggcggct
    17161 cgttcatctg gccatacacc agggatactt tgtcgataac gttggagtcg gtcatttcgt
    17221 ggtagaagtc gttaccctca cgagtacgtt cacctacgcc cgcaaacaca gagtaaccgg
    17281 agtgctcgat cgcgatgtta cgaatgagct ccatcatgtt tacggtttta cctacacccg
    17341 caccaccgaa cagaccaact ttaccgccct tagcgaacgg acacatcagg tcgataactt
    17401 tgataccggt ttccagcagt tcctgagagt ttgacagctc ttcgtaggaa ggtgctgcgc
    17461 ggtgaatcgc ccaacgctct tcttcaccga tctcgccttt catgtcgacc ggttcaccca
    17521 gtacgttcat gatacggccc agagtcgctt tacctaccgg gacttcaatc gggtgttcga
    17581 ggtcttttac atccagaccg cgacgcagac cgtcggagga acccattgcg atggtacgta
    17641 cgataccgcc gccgagctgc tgctgaactt ccagcaccag acgctcatta ccattttgca
    17701 cctcaagagc atcgtacacg cgcggtacgg catcctgagg gaattcgacg tcaactacgg
    17761 cgccgattac ctggacaatc tttccagtag ccatcttaaa tcctctacga aataacctgt
    17821 ttaaaccgcg gcggcccccg agacgatctc ggtgagttcc tgagtaatgc tggcctgacg
    17881 agctttgttg tataccaact gcagctcttt aatcaggctg ccgccattgt cggtcgcggc
    17941 tttcatcgcc accatacggg cggcctgctc gctggccagg ttttcaacca cgccctgata
    18001 aacctgagat tcgacataac gacgcagcag ggtatccagc aacgccttcg gatcgggttc
    18061 gtacaggtaa tcccaggatt tatgtttcag atcatcatca tctgatgccg gtaacggcag
    18121 cagctggctg atggtcggaa cctgagacat ggtgttaata aatttgttgc tgacaatgta
    18181 aagcttgtcc agacggcctt cgtcgtaggc ctgcaacatc acttttaccg gaccgatcag
    18241 ttcggacagg gaagggttat cccccatgcc ggtgacctgg gcaacaacat tgccgcccac
    18301 ggagttgaag aacgacacgc ctttcgagcc gatcattgcg aggtcgcatt gaacgccttt
    18361 gtcggtccag gtcttcattt ccgccagcag ttttttgaac aggttaatgt tcaaaccacc
    18421 gcacaaacca cggtcggtcg acaccaccag gtagcccacg cgtttaacgt cgcggtcttc
    18481 caggtaaggg tgcttatatt ccagattacc gtgtgcaagg tgaccaatca ctttgcgcat
    18541 ggtttctgca taaggacggc tggccgccat gcgatcctgc gatttacgca ttttggaagc
    18601 ggcgaccatc tccatcgctt tagtgatctt ttgcgtgttc tggacgcttg cgatcttact
    18661 acgtatctct tttgcgccgg ccatgagctt ctcctcaatg ccttgcggcc tgccctaagg
    18721 caagccgcca gacgttacca ggattgggtt gctttgaagg aatcgaggat gcctttcagc
    18781 ttgccttcga tttcgtcgtt gtagccaccg gtctggttga tctcttgcat caacggagcg
    18841 tgatcacggt cgacgtaagc cagcagagcg gcttcgaagc tgccaatttt cgacagttca
    18901 acatccgcca ggtaaccacg ttctgctgcg aacagaacca gagactgctg cgcaacggac
    18961 atcggcgcat actgtttctg tttcagcagt tcggtcactt tctgaccgtg gtcaagctgc
    19021 ttacgtgttg catcgtcaag gtcggatgca aactgagaga acgctgccag ttcacgatac
    19081 tgtgccagag cggtacggat accaccggac agttttttca tgatcttggt ctgtgctgca
    19141 ccaccaacac gggatacgga aatacccggg ttaaccgcag gacgaatacc ggcgttgaac
    19201 aggttggttt ccaggaagat ctgaccatcg gtaatggaga ttacgttggt cggaacgaac
    19261 gcagaaacgt cacccgcctg agtttcgata atcggcagtg cggtcagaga accggttttc
    19321 cctttcactt cacctttggt gaaggcttca acgtattcgg cgttaacacg tgcagcacgc
    19381 tccagcagac gagagtggag gtagaaaacg tcgcccggga atgcttcacg tcctggcgga
    19441 cgacggagca gcagggagat ctgacggtaa gcaacagcct gtttagacag gtcatcgtaa
    19501 atgatcagcg catcttcacc gcggtcacgg aagtattcgc ccattgcgca accggcatac
    19561 ggtgccaggt attgcagtgc agcggattca gacgcggttg ctaccacaac gatggtgtta
    19621 gccagtgcgc cgtgctcttc cagtttacgt accacgttag aaatggtgga cgctttctgg
    19681 ccgatagcga catagataca tttgataccg gaatcgcgct ggttgatgat ggcatcgata
    19741 gccagtgcgg ttttacctgt ctgacggtca ccgatgatca attcacgctg accacgaccg
    19801 attgggatca tggagtcaac ggctttataa ccggtctgta ccggctgatc tacggactga
    19861 cgttcgataa cgcccggagc gattgcttct acagcagaga agccgtcgtg atccagcgga
    19921 cctttaccgt cgattggtgc acccagagtg ttaaccacac ggcccagcag gccacggcca
    19981 accggaactt ccaggatacg gccagtacac ttaactttca tgccttcggc aaggtcagcg
    20041 tacggaccca taacaaccgc acctacagag tcgcgctcga ggttcagtgc gatagcgtaa
    20101 cggttacccg gcagggagat catttcaccc tgcatacaat cggccaggcc gtgaatgcgg
    20161 ataacaccgt cacttacaga aacaatagta ccttcgttgt gagcttcact cacaacattg
    20221 aactgagcaa tgcgctgctt gatcagttcg ctgatttcgg tggaattcag ttgcatgctc
    20281 cagtcccctt aagactgcaa gacgtctgca aggcgctcaa gacgaccgcg tacgctgcca
    20341 tcaatgacca tatcacccgc tcggatgata acgcctgcca ttacagactt atcgattttg
    20401 caattcagct taactttgcg tgacagacgt ttttccatcg cagcagaaat tttcgcgagc
    20461 tgttgttcac tcagtgcggc agcggaaatg acgtctacct cagcggtagc ctcactcacg
    20521 gcacgcaggt gaataaactg ctccagaaca tccgggagcg cgttaagacg accattttca
    20581 gccataaccc gaatcaggtt ctgaccgttt tcgtccagtt gctcaccaca aactgcgata
    20641 aacgactcgg cgagcgtttc tggcgcaagc gcgccagaga gaagctctgc catttgttcg
    20701 tttttggtta cctcggcggc aaacgccagc atgtcctgcc agcgttctac actttggtgt
    20761 tcgacggcaa agtcaaaagc tgctttggcg taggggcgag ctaccgtaat aaattcagac
    20821 atcagcccct ccctccttac agttcagcga caagtttatc cacgatgtcg ctgttagcag
    20881 cttcatccac ggaacgttcg atgatcttct cggcgccagc aacagccagg atagcaactt
    20941 gcttacgcag ctcttcacgg gcacgtttac gctcggcttc aatttccgcc tgcgcctggg
    21001 ccacgatttt agtacgttcc tgttctgcct cagctttcgc ttcgtccaga atctgcgagc
    21061 ggcgtttgtt cgcctgctcg atgattacct gggcttccgc tttcgctttt ttcagctggt
    21121 cggtcgcgct ggcctttgca aggtcaaggt ccttatgtgc tcgttctgcg gaagcaaggc
    21181 cgtcagcaat ttctttttga cgtttttcga tggctgccat taatggcggc catacgtact
    21241 tcatgcagaa cagaacgaac aggacaaacg cgatggcctg gccgaggatt gttgcgttaa
    21301 gattcacagc acaatgcctc tatttagtta acgttctgat attgctcttt aaataaaagc
    21361 aacgcttact acgcgacagc gaacatcacg tacagaccca gacctacagc gatcatcggg
    21421 atagcatcca ccagacccat aacgataaag aactgagtac gcagcagagg aatcagatca
    21481 ggttgacgcg ctgcgccttc caggaattta cccccgagga tgccgatacc gatcgcagca
    21541 ccgattgccg ccagacccat catcacagcg gcagccatgt acagcagatc catattcagg
    21601 ttttccatga cagtctccag tttgtttcag ttaaaacgta gtagtgttgg taaattaatg
    21661 ttcttcagac gccatcgaca gatagacgat cgtcagaacc atgaagatga aggcttgcag
    21721 cgtaatgatc aggatgtgga aaatggccca cggcacattc aggatccact gtgaccacca
    21781 cggcaacaga ccagcaatca gaatgaaaat cagctcaccg gcatacatgt taccgaacag
    21841 tcgcaaaccg agtgaaactg gtttggacag caggcttacc ccttcaagga ttaagttgac
    21901 aggaatgaac gcccagtgat tgaacggctg cagcgtcaac tctttcgtga agccgccgat
    21961 gcctttcatt ttgatgctgt agaacagaat caggataaat acgcccagtg ccatagacag
    22021 cgttacgttc acgtccgcag acggaaccac acgcagtgca ggcagaccca gtacatgttc
    22081 agcaatgtac ggcagcaggt cgataggcag taaatccatc aggttcatca ggaataccca
    22141 gacgaagatc gtcagggcca gcggagcaat cagcttgctt ttgccatggt acatgtcttt
    22201 cacgctacca ttaacaaagc cgatcaccag ctcaatcgcg gtctgaaact tacctggcac
    22261 accgctggtc gcctttttgg ctacgctacg gaataaaacc aggaacaaca gacccagcac
    22321 caccgagaag aacatggagt caatattgat tgtccagaag gtggctgggg ggttttgtgg
    22381 atccaccagc gagaatgtac gcaggtccag ctgaaggtta ttcaggtggt gtcctatgta
    22441 atcctgcggc gtcatatttt ctgaagccat gatgcctttt accctttgtt gttaattaca
    22501 gccggtgcca gtatctgaac caccagcacc aaaacccacg taacgatcag cggcaagaat
    22561 accgccttta aaaccgccaa cgccaccacc agtaacacca acatcgccag aactttgaaa
    22621 gcttcgccaa atgcgaatgt ccaggccacc cggcctttcg ctggtgtatg cgcctggtga
    22681 cgccaggcaa atatcataaa caaaacgtta ggcagaaaga ctgccaggcc cccgcttatt
    22741 gcagagacgc cccagaaggg gtctttgagg ctgaacagca atccacttgc tatcaccacc
    22801 agtaactgaa cgagcagaag cttccgagca acgtttcgac tcacgagcga cacagacatc
    22861 acgtttttca ctcctgctcc cttcgaggta tgccgcgtgt cgtataaaac tttctttaag
    22921 gcttagagtc aagcatcaaa aagcggtcaa attatacggt gcgcccccgt gatttcaaac
    22981 aataagtagc caaaaggtga ataaatgttt aaatattttt ccagtgcata caattgcgac
    23041 ttttctgcta accctgttcg atcatgaaaa actgtaaata acgcgtaaac actggtgata
    23101 aagcgtgctt cagatcacat attgcgcatg ttcgcgcaca gcatatttat ttacttggca
    23161 aatgatgcct ttgcaagttt atgatatttc agtctaaaaa cagatactgt tttaataaat
    23221 gacatttaca caacaaaaac cacccattga catttttaat aatgttttaa cagccaatga
    23281 tggttcttag cgccgatttt tagcagactg atattttcac taatgactta ttttctgctt
    23341 accaaaaaaa gccacgttat cttgttgatg caaaagagtg aa
//
LOCUS       DAPGUL010000378        17505 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.guided.094, whole genome shotgun sequence.
ACCESSION   DAPGUL010000378 DAPGUL010000000
VERSION     DAPGUL010000378.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17505
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.guided.094"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            complement(251..796)
                     /gene="orn"
                     /locus_tag="RHX21_005021"
     CDS             complement(251..796)
                     /gene="orn"
                     /locus_tag="RHX21_005021"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoribonuclease"
                     /protein_id="HDV1990037.1"
                     /translation="MSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGP
                     TIAVHQSDEQLALMDDWNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVPAGKS
                     PICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQA
                     MDDIRESVAELAYYREHFIKL"
     gene            891..1943
                     /gene="rsgA"
                     /locus_tag="RHX21_005022"
     CDS             891..1943
                     /gene="rsgA"
                     /locus_tag="RHX21_005022"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313167.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small ribosomal subunit biogenesis GTPase RsgA"
                     /protein_id="HDV1990038.1"
                     /translation="MSKNKLSKGQQRRVNANHQRRLKTSKEKPDYDDNLFGEPDEGIV
                     ISRFGMHADVESADGDVHRCNIRRTIRSLVTGDRVVWRPGKPAAEGVNVKGIVEAVHE
                     RTSVLTRPDFYDGVKPIAANIDQIVIVSAILPELSLNIIDRYLVACETLQIEPIIVLN
                     KIDLLDDEGMAFVNEQMDIYRNIGYRVLMVSSHTQDGLKPLEEALTGRISIFAGQSGV
                     GKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHFPHGGDVIDSPGVREFGLW
                     HLEPEQITQGFVEFHDYLGLCKYRDCKHDTDPGCAIREAVEEGKIAETRFENYHRILE
                     SMAQVKTRKNFSDTDD"
     gene            2040..3008
                     /gene="psd"
                     /locus_tag="RHX21_005023"
     CDS             2040..3008
                     /gene="psd"
                     /locus_tag="RHX21_005023"
                     /EC_number="4.1.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313166.1"
                     /note="Phosphatidylserine decarboxylase is synthesized as
                     a single chain precursor. Generation of the pyruvoyl
                     active site from a Ser is coupled to cleavage of a Gly-Ser
                     bond between the larger (beta) and smaller (alpha chains).
                     It is an integral membrane protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylserine decarboxylase"
                     /protein_id="HDV1990039.1"
                     /translation="MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKY
                     YKVDMKEAQKPDTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEED
                     KILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYV
                     PGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTIT
                     PPREGIIKRWTWPAGENDGSVALLKGQEMGRFKLGSTVINLFAPGKVNLVEQLESLSV
                     TKIGQPLAVSTETFVTPDAEPAPLPAEEIEAEHDASPLVDDKKDQV"
     gene            3030..6353
                     /gene="mscM"
                     /locus_tag="RHX21_005024"
     CDS             3030..6353
                     /gene="mscM"
                     /locus_tag="RHX21_005024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="miniconductance mechanosensitive channel MscM"
                     /protein_id="HDV1990040.1"
                     /translation="MRLIITFLMAWCLSWGAYAATAPDSKQITQELEQAKAAKPAQPE
                     VIEALQSALNALEERKGSLERIKQYQQVIDNYPKLSATLRAQLNNMRDEPRSVSPGMS
                     TDALNQEILQVSSQLLDKSRQAQQEQERAREIADSLNQLPQQQTDARRQLNEIERRLG
                     TLTGNTPLNQAQNFALQSDSARLKALVDELELAQLSANNRQELARLRSELAEKESQQL
                     DAYLQALRNQLNSQRQLEAERALESTELLAENSADLPKDIVAQFKINRELSAALNQQA
                     QRMDLVASQQRQATSQTLQVRQALNTLREQSQWLGSSNLLGEALRAQVARLPEMPKPQ
                     QLDTEMAQLRVQRLRYEDLLNKQPQLRQIHQADGQPLTAEQNRILEAQLRTQRELLNS
                     LLQGGDTLLLELTKLKVSNGQLEDALKEVNEATHRYLFWTSDVRPMTIAWPLEIAQDL
                     RRLISLDTFSQLGKASVMMLTSKETILPLFGALILVGCSIYSRRYFTRFLERSAAKVG
                     KVTQDHFWLTLRTLFWSILVASPLPVLWMTLGYGLREAWPYPLAVAIGDGVTATVPLL
                     WVVMICATFARPNGLFIAHFGWPRERVSRGMRYYLMSIGLIVPLIMALMMFDNLDDRE
                     FSGSLGRLCFILICGALAVVTLSLKKAGIPLYLNKEGSGDNITNHMLWNMMIGAPLVA
                     ILASAVGYLATAQALLARLETSVAIWFLLLVVYHVIRRWMLIQRRRLAFDRAKHRRAE
                     MLAQRARGEEEAHHHSSPEGAIEVDESEVDLDAISAQSLRLVRSILMLIALLSVIVLW
                     SEIHSAFGFLENISLWDVTSTVQGVESLEPITLGAVLIAILVFIITTQLVRNLPALLE
                     LAILQHLDLTPGTGYAITTITKYLLMLIGGLVGFSMIGIEWSKLQWLVAALGVGLGFG
                     LQEIFANFISGLIILFEKPIRIGDTVTIRDLTGSVTKINTRATTISDWDRKEIIVPNK
                     AFITEQFINWSLSDSVTRVVLTIPAPADANSEEVTEILLTAARRCSLVIDNPAPEVFL
                     VDLQQGIQIFELRIYAAEMGHRMPLRHEIHQLILAGFHAHGIDMPFPPFQMRLESLNG
                     KQTGRTLTSAGKGRQAGSL"
     gene            complement(6504..8006)
                     /gene="yjeM"
                     /locus_tag="RHX21_005025"
     CDS             complement(6504..8006)
                     /gene="yjeM"
                     /locus_tag="RHX21_005025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418580.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/gamma-aminobutyrate family transporter
                     YjeM"
                     /protein_id="HDV1990041.1"
                     /translation="MPHTIKKMSLIGLILMIFTSVFGFANSPSAYYLMGYSAIPFYIF
                     SALLFFIPFALMMAEMGAAYRKEEGGIYSWMNNSVGPRFAFIGTFMWFSSYIIWMVST
                     SAKVWVPFSTFLYGSDMTQHWRIAGLEPTQVVGLLAVAWMILVTVVASKGINKIARIT
                     AVGGIAVMCLNLVLLLVSITILLLNGGHFAQDINFLASPNPGYQSGLAMLSFVVFAIF
                     AYGGIEAVGGLVDKTENPEKNFAKGIVFAAIVISIGYSLAIFLWGVSTNWQQVLSNGS
                     VNLGNITYVLMKSLGVTLGNALHLSPEASLSLGVWFARITGLSMFLAYTGAFFTLCYS
                     PLKAIIQGTPKALWPEPMTRLNAMGMPSIAMWMQCGLVTVFILLVSFGGGTASAFFNK
                     LTLMANVSMTLPYLFLALAFPFFKARQDLDRPFVIFKTHLSAMIATVVVVLVVTFANV
                     FTIIQPVVEAGDWDSTLWMIGGPVFFSLLAMAIYQNYCSRMANKPELALD"
     gene            complement(8225..9202)
                     /gene="epmA"
                     /locus_tag="RHX21_005026"
     CDS             complement(8225..9202)
                     /gene="epmA"
                     /locus_tag="RHX21_005026"
                     /EC_number="6.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P--(R)-beta-lysine ligase"
                     /protein_id="HDV1990042.1"
                     /translation="MSETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMS
                     QATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNE
                     EMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEID
                     PLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPAS
                     QASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQ
                     HPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA"
     gene            9527..11335
                     /gene="frdA"
                     /locus_tag="RHX21_005027"
     CDS             9527..11335
                     /gene="frdA"
                     /locus_tag="RHX21_005027"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase (quinol) flavoprotein
                     subunit"
                     /protein_id="HDV1990043.1"
                     /translation="MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRS
                     HTVAAEGGSAAVAQDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGC
                     PWSRRPDGSVNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLD
                     ILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMAL
                     SHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLG
                     EPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICE
                     LAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRL
                     GSNSLAELVVFGRLAGEQATERAATAGNGNEAAIEAQAAGVEQRLKDLVNQDGGENWA
                     KIRDEMGLAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIE
                     LGHGLNVAECMAHSAMARKESRGAHQRLDEGCTERDDVNFLKHTLAFRDADGTTRLEY
                     SDVKITTLPPAKRVYGGEADAADKAEAANKKEKANG"
     gene            11328..12062
                     /gene="frdB"
                     /locus_tag="RHX21_005028"
     CDS             11328..12062
                     /gene="frdB"
                     /locus_tag="RHX21_005028"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase iron-sulfur protein"
                     /protein_id="HDV1990044.1"
                     /translation="MAEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYI
                     KDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERD
                     LVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACP
                     QFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKH
                     VDPAAAIQQGKVESSKDFLIATLKPR"
     gene            12073..12468
                     /gene="frdC"
                     /locus_tag="RHX21_005029"
     CDS             12073..12468
                     /gene="frdC"
                     /locus_tag="RHX21_005029"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdC"
                     /protein_id="HDV1990045.1"
                     /translation="MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELI
                     FGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDE
                     KMGPEPIIKSLWAVTVVATIVILFVALYW"
     gene            12479..12838
                     /gene="frdD"
                     /locus_tag="RHX21_005030"
     CDS             12479..12838
                     /gene="frdD"
                     /locus_tag="RHX21_005030"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdD"
                     /protein_id="HDV1990046.1"
                     /translation="MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGL
                     FPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFY
                     GLAAILTVVTLIGIVTI"
     gene            12901..14034
                     /locus_tag="RHX21_005031"
     CDS             12901..14034
                     /locus_tag="RHX21_005031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaEC family class C beta-lactamase"
                     /protein_id="HDV1990047.1"
                     /translation="MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGM
                     AVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLS
                     DPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAP
                     GTQRLYANSSIGLFGALAVKPSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWG
                     YREGKAVHVSPGALDAETYGVKSTIEDMACWVRSNMNPRDINDKTLQQGIQLAQSRYW
                     QTGDMYQGLGWEMLDWPVNPDSIINGSGNKIALAAHPVKAITPPTPAVRASWVHKTGA
                     TGGFGSYVAFIPEKELGIVMLANKNYPNPARVAAAWQILNALQ"
     gene            14123..14656
                     /gene="blc"
                     /locus_tag="RHX21_005032"
     CDS             14123..14656
                     /gene="blc"
                     /locus_tag="RHX21_005032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin Blc"
                     /protein_id="HDV1990048.1"
                     /translation="MRLLPLVAAATAAFLVVACSSPTPPRGVTVVNNFDAKRYLGTWY
                     EIARFDHRFERGLEKVTATYSLRDDGGLNVINKGYNPDRGMWQQSEGKAYFTGAPTRA
                     ALKVSFFGPFYGGYNVIALDREYRHALVCGPDRDYLWILSRTPTISDEVKQEMLAVAT
                     REGFDVSKFIWVQQPGS"
     gene            complement(14653..14970)
                     /gene="sugE"
                     /locus_tag="RHX21_005033"
     CDS             complement(14653..14970)
                     /gene="sugE"
                     /locus_tag="RHX21_005033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418572.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HDV1990049.1"
                     /translation="MSWIILVIAGLLEVVWAVGLKYTHGFSRLTPSVITVTAMIVSMA
                     LLAWAMKSLPVGTAYAVWTGIGAVGAAITGIVLLGESANPMRLASLALIVLGIIGLKL
                     STH"
     gene            complement(15145..15291)
                     /gene="ecnB"
                     /locus_tag="RHX21_005034"
     CDS             complement(15145..15291)
                     /gene="ecnB"
                     /locus_tag="RHX21_005034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein toxin entericidin B"
                     /protein_id="HDV1990050.1"
                     /translation="MVKKTIAAIFSVLVLSTVLTACNTTRGVGEDISDGGNAISGAAT
                     KAQQ"
     gene            complement(15402..15527)
                     /gene="ecnA"
                     /locus_tag="RHX21_005035"
     CDS             complement(15402..15527)
                     /gene="ecnA"
                     /locus_tag="RHX21_005035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein antitoxin entericidin A"
                     /protein_id="HDV1990051.1"
                     /translation="MMKRLIVLVLLASTLLTGCNTARGFGEDIKHLGNSISRAAS"
     gene            complement(15579..16145)
                     /gene="efp"
                     /locus_tag="RHX21_005036"
     CDS             complement(15579..16145)
                     /gene="efp"
                     /locus_tag="RHX21_005036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004871142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HDV1990052.1"
                     /translation="MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLR
                     RLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGD
                     NAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGA
                     VVKVPLFVQIGEVIKVDTRSGEYVSRVK"
     gene            16187..17215
                     /gene="epmB"
                     /locus_tag="RHX21_005037"
     CDS             16187..17215
                     /gene="epmB"
                     /locus_tag="RHX21_005037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF-P beta-lysylation protein EpmB"
                     /protein_id="HDV1990053.1"
                     /translation="MAHIVTLNTPSREDWLTQLADVVTDPDELLRLLNIDADEKLLAG
                     RSAKKLFALRVPRSFIDRMEKGNPDDPLLRQVLTSQDEFVVASGFSTDPLEEQHSVVP
                     GLLHKYHNRALLLVKGGCAVNCRYCFRRHFPYAENQGNKRNWQTALEYVAAHPELDEM
                     IFSGGDPLMAKDHELDWLLTQLEAIPHIKRLRIHSRLPIVIPARITEALVERFARSTL
                     QILLVNHINHANEVDETFRQAMAKLRRVGVTLLNQSVLLRGVNDNAQTLANLSNALFD
                     AGVMPYYLHVLDKVQGAAHFMVSDDEARQIMRELLTLVSGYLVPKLAREIGGEPSKTP
                     LDLQLRQQ"
BASE COUNT         4351 a         4611 c         4514 g         4029 t
ORIGIN      
        1 ccttggcaag gtcgtgctct accaactgag ctattcccgc gtactactta attttgcttt
       61 cgtaattttc gcatttctgc gtcgttacgg gaggcgcatt atacgagaaa tctttccctc
      121 tgcaaccccc caaaaaagtt ttttttgcgt ttttatctca agtgctgaaa ttatcagcaa
      181 gacgttcaat ttagcgtcaa aatcacgccg ccgcaagtgg attccggcgc ttacgtgacc
      241 aggaaaaatt ttacagcttg ataaaatgct cgcggtagta agccagctcc gccaccgatt
      301 cacggatatc atccatcgcc tgatgcgtcc cctgcttggt aaaaccatcc agaatttccg
      361 gcttccagcg gcgcgccagc tctttcaggg tgctgacatc gagataacgg tagtggaagt
      421 aggcttccag ctccggcatg tatttaaaca ggaaacgacg gtcctgaccg atgctgttac
      481 cgcaaatcgg cgattttccc gcaggcaccc actgttttaa aaattcgagc gttgccagtt
      541 cagcttcccg atcgcccatc gtgctcgctt tcacgcgctc taccagcccg ctggcggtat
      601 gggtgcgcac gttccagtca tccatcagcg ccagctgttc atcagactgg tgtactgcaa
      661 tggtcggccc ttctgccaga atattcaggt tggcatcggt caccagcgtg gcaatctcaa
      721 taatgcgatc gcgctcggga tccagaccgg tcatctcaag atcgatccaa atcaggttgt
      781 tttcattggc actcatgcta ttttccaccc attcacagtg actatattga tccacaattg
      841 cgtgtatcat agatgttttg cccatcaggg gcgaccagga gtctgtacga ttgagtaaaa
      901 ataaactctc caaaggccag cagcgccgcg tgaacgccaa tcaccagcgt cgtcttaaaa
      961 cgtctaagga gaagcccgac tacgacgaca atctgtttgg cgagcctgat gaaggtatcg
     1021 tcatcagccg ctttggtatg cacgctgatg tggaatccgc cgatggcgac gttcaccgct
     1081 gcaatattcg ccgtaccatc cgttcgctgg taaccggcga ccgcgtagtc tggcgtccgg
     1141 gtaaaccggc ggcggaaggc gtaaatgtca aagggatcgt ggaagcggtg catgagcgca
     1201 cctcagtgtt gacgcgtccg gatttctacg acggcgtgaa acctattgcc gccaacatcg
     1261 accagattgt cattgtctcc gccattttgc cggagctgtc gctcaatatt atcgaccgtt
     1321 acctggtggc ctgcgaaacc ttgcagattg agccgattat tgtgctcaat aagatagacc
     1381 tgctggacga cgaaggcatg gcgttcgtca acgagcagat ggatatctac cgcaacattg
     1441 gttatcgcgt attgatggtt tccagccata ctcaggatgg gctaaaaccg ctggaagagg
     1501 cgttgaccgg gcgcatcagc atttttgccg gccagtctgg cgtcggcaaa tccagcctgc
     1561 tgaacgcgtt gctggggctg caaaaagaga tcctgaccaa cgatgtctct gacaactcgg
     1621 gtctcggtca gcacaccacg accgccgcac gactgtatca cttcccgcac ggcggtgatg
     1681 tgattgattc ccctggtgtg cgtgagttcg gcctctggca cctggagccg gaacaaatca
     1741 ctcagggctt tgtcgaattc catgactatt taggtctgtg taaatatcgc gattgcaaac
     1801 acgataccga tccgggctgc gctatccggg aagcggttga ggaaggaaaa atcgcggaaa
     1861 cccgtttcga aaactatcac cgtattctgg aaagcatggc gcaggtaaaa acgcgtaaaa
     1921 acttttctga tacggatgac tgacaattaa gctaaccgtc gttagaatcg tccccttttt
     1981 ttcaggatcc ggcatgtagg ccggatcagg aacgacaaaa caatggcctg gaggctacct
     2041 tgttaaattc atttaaactt tcgctacagt acattctgcc gaaactatgg cttactcgcc
     2101 tggcgggttg gggcgcaagc aagcgggcag gatggctgac aaaactggtt atcgatctgt
     2161 tcgttaaata ctacaaggtc gacatgaaag aggcgcaaaa gccggacacc gccagctacc
     2221 gcacctttaa cgaattcttt gtccgtccgc tgcgtgacga agtacgccca atcgataccg
     2281 atccgaatgt cctggtcatg cctgccgatg gcgttatcag ccagttgggt aaaatcgaag
     2341 aagataaaat cctgcaagcc aaaggccaca actacagcct cgaagccttg ctggcaggca
     2401 actatctgat ggcggacctg ttccgcaacg gtacgtttgt gaccacttac ctctccccgc
     2461 gtgactacca ccgcgtacac atgccgtgca acggtattct gcgtgagatg atctacgtgc
     2521 cgggcgatct cttctccgtt aaccatctca ccgctcagaa cgtgccgaat ctgtttgccc
     2581 gtaacgaacg cgtgatttgc cttttcgata ccgaatttgg cccaatggcg cagattctgg
     2641 tcggagcgac gattgttggc agcattgaga cggtctgggc gggcaccatt acgccgccgc
     2701 gcgaaggtat catcaagcgc tggacctggc ctgccgggga aaacgacggt tctgtggcac
     2761 tgcttaaagg ccaggaaatg ggtcgcttta aactcggttc caccgttatc aacctgtttg
     2821 caccgggtaa agtgaatctg gttgagcaac tggaaagcct gtctgtcacg aaaattggcc
     2881 agccgctggc agtatctacc gaaacctttg ttacgccaga cgctgaacct gccccgcttc
     2941 ctgctgaaga gatcgaagca gaacacgacg ccagcccatt ggttgacgac aaaaaagacc
     3001 aggtctaatc catcaaagga aacgctgacg tgcgcctgat tatcactttt ctgatggcct
     3061 ggtgcctcag ttggggggcg tacgccgcga cggcccccga tagcaaacaa atcacccagg
     3121 aactggagca ggcaaaagcg gcgaaacccg cgcagccaga agtcatagag gcactccagt
     3181 ctgccttaaa tgcgcttgag gaacgaaaag gttcccttga gcgcatcaaa caatatcagc
     3241 aagttatcga taattacccg aaactctccg ctactctgcg cgcacaatta aacaacatgc
     3301 gtgacgagcc gcgcagcgtg tcgccgggaa tgtctaccga tgcgctgaat caggaaattc
     3361 tccaggtcag cagtcagttg ctggataaga gccgtcaggc ccagcaagag caggagcgcg
     3421 cccgcgagat tgccgattca ctgaatcaac tgccgcaaca gcaaaccgat gcccgccgtc
     3481 agttaaatga gatcgagcgc cgcctgggaa cgcttaccgg caatactccg ctcaatcagg
     3541 cacaaaattt cgcgttgcag tctgactccg cacgcctgaa agcgctcgtt gatgaactgg
     3601 aactggcgca gctgtctgcc aataaccgtc aggaattagc gcgcttgcgc tcagagctgg
     3661 cggaaaaaga gagccagcaa ctggatgcgt atttgcaggc cttacgtaat cagttgaata
     3721 gccaacgtca gcttgaggcg gagcgggcgc tggaaagtac cgaattactg gcagaaaaca
     3781 gtgccgattt gccgaaagat atcgtcgcgc aattcaaaat taaccgcgaa ctatcggcgg
     3841 cactgaatca acaggcgcag cggatggatc tcgttgcctc gcaacagcgc caggccacca
     3901 gccagacgtt acaggtccgg caggcgttga atacgctgcg tgaacagtcg caatggctgg
     3961 gctcgtccaa cctgctcggc gaagcgttgc gggcgcaggt ggcacggctg ccggaaatgc
     4021 caaaaccaca acaacttgat accgaaatgg cgcagttgcg tgtgcaacgg ttacgttatg
     4081 aggatctgct taataaacag ccgcagctaa ggcaaattca tcaggccgac ggtcagccgc
     4141 tgaccgccga gcaaaaccgt attctggaag cacagctacg cactcagcgt gagttgctga
     4201 actcattgtt gcagggtgga gacacgctac tgctggaact gaccaagctg aaagtctcca
     4261 acgggcaact ggaggatgcg ctgaaagagg tgaacgaagc gacgcaccgc tatctgttct
     4321 ggacctctga cgtgcgcccg atgactatcg cctggccgct ggaaatcgcc caggatctgc
     4381 gccgcctcat ctcgctggac accttcagtc agttgggtaa agccagcgtg atgatgctga
     4441 ccagcaaaga gacgattttg ccgctgtttg gcgcgttgat tctggtcggt tgcagtattt
     4501 actcgcgccg ctatttcacc cgttttcttg aacgttcggc ggcgaaagtc ggcaaagtga
     4561 ctcaggatca cttctggctg acgttgcgca ctcttttctg gtcgattctc gtcgcgtcac
     4621 cgctgccggt gctgtggatg acgctgggtt acggcttgcg cgaggcgtgg ccttatccgc
     4681 tggcggtcgc gattggcgat ggcgtaacgg ccaccgtgcc gctgctgtgg gtagtgatga
     4741 tttgcgccac ctttgcccgc ccgaacggct tgtttatcgc tcattttggc tggccgcgcg
     4801 aacgtgtttc ccgtgggatg cgctactacc tgatgagcat cgggcttatt gtgccgctga
     4861 ttatggcgct gatgatgttc gataacctcg acgaccgtga attctccggt tcgctgggac
     4921 ggctttgctt tatcctcatt tgcggtgcgc tggcggtggt caccctcagc ctgaaaaagg
     4981 ccgggatccc gctgtacctc aacaaagagg gcagcggcga caacattacc aaccatatgc
     5041 tgtggaacat gatgattggc gcaccactgg ttgccattct ggcgtcagcg gtgggttatc
     5101 tggcaacggc gcaggcactg ttagcgaggc ttgaaacctc ggttgccatc tggttcctgc
     5161 tactggtggt ttatcacgtt atccgccgct ggatgctgat ccagcgtcgc aggctggcgt
     5221 ttgaccgggc gaagcatcgc cgggcagaga tgttagcgca acgcgcgcgt ggcgaagagg
     5281 aagcgcatca tcacagtagc ccggaagggg caattgaagt cgatgaaagc gaagtcgatc
     5341 tcgatgccat cagtgcgcaa tccttgcggc tggtgcgctc aattttgatg ttgatcgccc
     5401 tgctttctgt cattgtgctg tggtcagaaa tccattccgc tttcggcttc ctcgaaaata
     5461 tttcgctgtg ggatgtcacc tccacggtac agggcgtaga aagtctggag ccaattaccc
     5521 tcggtgcggt gctgattgcc attctggtgt ttatcatcac cacgcagctg gtgcgcaacc
     5581 tgcccgcgct gctggaactg gcgattttgc agcacctgga tttaacgccg ggtacgggct
     5641 acgccatcac caccatcacc aaatatctgc tgatgctgat tggcgggctg gtcggcttct
     5701 cgatgattgg tattgagtgg tcgaaattgc agtggctggt tgccgcgctc ggtgttggtc
     5761 tcggttttgg tttgcaggag attttcgcca actttatctc tggcctgatt atcctgttcg
     5821 aaaaaccgat tcgcattggc gatacggtaa cgatccgcga tcttaccggt agcgtgacga
     5881 aaattaacac ccgcgccacc accatcagcg actgggaccg taaagagata atcgtgccga
     5941 acaaggcgtt tattaccgag cagtttatca actggtcgct ctctgactcg gtcacgcgcg
     6001 tggtgttgac gataccggcc cctgccgatg ccaatagcga agaagtgacg gaaatcctgc
     6061 tcaccgcagc gcgtcgctgc tcgctggtga tcgacaaccc ggcaccggaa gtcttcctgg
     6121 tggatctgca acaggggatt cagattttcg agctgcgtat ttacgccgct gagatgggtc
     6181 accgtatgcc gctacgccat gagatccacc agctgattct ggcaggcttc cacgcccacg
     6241 gtatcgatat gccattcccg cccttccaga tgcgtctgga aagcctcaac ggtaagcaaa
     6301 cggggagaac attaacttct gcgggcaaag gtcgtcaggc gggaagtttg taatgcatga
     6361 agctgccaaa tgatgtcaac gtggctcatt tagcagctta acatcatctt cagttatcac
     6421 cggccctgga gagtatcatc catacgcatt acttcctgac aactcatcgc cggagagacg
     6481 atgagttgca ggatttcata tgatcagtcg agagctaact caggtttatt cgccatgcga
     6541 ctgcaatagt tctggtaaat cgccatcgct aacagcgaga agaagacagg gccgccaatc
     6601 atccacaatg tgctgtccca gtctccggct tcaaccacag gttgaatgat ggtgaagacg
     6661 ttcgcaaatg tcaccaccag tacgacaacc actgtcgcaa tcattgccga caaatgcgtt
     6721 ttgaaaatca caaacggtct gtcgagatcc tgacgtgctt taaagaacgg gaaagccagc
     6781 gcgaggaaca ggtaaggaag cgtcatagac acgttcgcca tcagcgtcag cttgttaaag
     6841 aacgccgatg cggtaccgcc accaaacgaa accagcagga tgaagacagt aaccaacccg
     6901 cactgcatcc acatggcgat agaaggcatc cccatcgcat tcaggcgcgt catcggttcc
     6961 ggccacaacg ctttcggcgt cccctggatg atggctttca gcggtgaata gcaaagcgta
     7021 aagaacgccc cggtataagc gaggaacatc gaaagtccgg taatacgcgc aaaccataca
     7081 cccagcgaca atgacgcttc aggtgacaaa tgcagtgcgt tacccagcgt caccccgagg
     7141 ctcttcatca gcacataggt aatattgccg aggttaacgg aaccattact taatacctgc
     7201 tgccagtttg tgctgacacc ccataaaaat attgccagcg aataaccgat tgaaataaca
     7261 atagcggcaa aaacaatacc tttggcaaag ttcttttctg gattttccgt tttatcgacc
     7321 agaccaccaa ccgcttcaat tccgccatag gcaaaaatag caaataccac aaacgatagc
     7381 attgccagac cggactgata acctgggttc ggtgatgcaa ggaaattaat atcctgcgcg
     7441 aaatgcccac catttaataa caaaatagta atgcttacta acagcaatac taaattcaga
     7501 cacattactg caataccgcc caccgcagta atgcgggcaa ttttattaat cccctttgaa
     7561 gcaacgacgg tgaccagaat catccatgcc actgccagca gaccaaccac ctgcgtaggc
     7621 tccagtccag caatacgcca gtgctgggtc atgtcgctac catagaggaa tgttgagaac
     7681 ggtacccaaa ctttcgcgga ggtactcacc atccagatga tataagagga aaaccacata
     7741 aacgtaccaa tgaaggcaaa acgtggtccg acactattat tcatccagga atagatacca
     7801 ccttcttctt tgcgataggc agctcccatt tcagccatca ttaaggcgaa tggaataaag
     7861 aataacaatg cagaaaatat ataaaaggga atcgcactat aacccattaa gtaataagcc
     7921 gatgggctat tggcaaatcc aaatacggaa gtaaagatca tcaatatgag tcctatcaga
     7981 ctcatctttt ttatcgtgtg aggcatgaaa ccatccttca tttcagcgcg tgtataaaac
     8041 gcgcccactg aactgcactg cccaacattg agcgggcagc gtaaaaacca atacagaatt
     8101 gatacctgga tgatatcaaa tatccagtct taaattgtgg cctttaacgg aaaaatgaaa
     8161 acatatgcta cagaatggcg cttatcacgc cattcttcgc tgttaattca gtaatttttc
     8221 agaattatgc ccggtcaacg ctaaaggcga tgacttcagc cagtgtctcc gcgcccagcg
     8281 ccaacatcac cagacgatca acacctaatg ccacgccgga acagtcaggc ataccgactt
     8341 tcaaggcttc aatcagattc tggtcaatgg ggtgctgcgg caaaccgcgc gccgcgcgct
     8401 tacggttatc ttgttcaaag cgttgttgct gctcacgggc atccgtcaat tcatggaaac
     8461 cattcgccag ctcaatacct ttataataaa cctcaaagcg ttcagcgacc cgatgatctt
     8521 cggtactgat ttgcgccagt gatgcctggc tggctggaaa gtggtacaca aaggtcggtt
     8581 tttctttgcc aatatttggc tctacgccaa aggtaaacag caattgtagc agcgtgtcgc
     8641 ggtcttcttc ggtatcagca acattgctca aatccagttt cgctgcgact tcccgcagtt
     8701 gcgttttgtc ggcagagagc gggtcaattt ccagataacg caagaaagct tgttgataag
     8761 aaaggctttc tgctgccggg cagtccagca cctgttgtaa gagatcgtcc acctcgttca
     8821 tcaaccggta catatcatag tgcggtcgat accactccag catagtgaac tcagggttgt
     8881 gataacgccc catctcttca ttacggaagc tgcggcacag ctggaatacc ggcccacaac
     8941 cggcaaccag caggcgtttc atatggtatt ccgggctggt cattaaccag agattcatcc
     9001 cctgcgaatg cccggggcca acgaaacgtg tctcaaacgg gaccaaatga atatcggtta
     9061 ccgtcgcctg gctcatacaa ggcgtctcca cctccagcac tccacgatcg gcaaagaaac
     9121 gacggatctc cgccataatc gccgcgcgtt ttaataagtt aggaatggat gcgctcggct
     9181 gccaggatgc cgtttcgctc atagttaaat ctccagtttt tgacaagggc acgaagtcta
     9241 ctcgcaacgc gacggcgaga caaattttac gcaggaatca aacagcggtg ggcagtgact
     9301 aaaaaaagca cgatctgatg gtttagtaat taaattaatc atcttcagtg ataatttagc
     9361 cctcttgcgc actaaaaaaa tcgatctcgt caaatttcag acttatccat cagactatac
     9421 tgttgtacct ataaaggagc agtggaatag cgttcgcaga ccgtaacttt caggcactta
     9481 ccctgaagta cggggctgtg ggataaaaac aatctggagg aatgtcgtgc aaacctttca
     9541 agccgatctt gccattgtag gcgccggtgg cgcgggatta cgtgctgcaa ttgctgccgc
     9601 gcaggcaaat ccaaatgcaa aaatcgcact aatctcaaaa gtatacccga tgcgtagcca
     9661 taccgttgct gcagaagggg gctccgccgc tgtcgcgcag gatcatgaca gcttcgaata
     9721 tcactttcac gatacagtag cgggtggcga ctggttgtgt gagcaggatg tcgtggatta
     9781 tttcgtccac cactgcccaa ccgaaatgac ccaactggaa ctgtgggggt gcccatggag
     9841 ccgtcgcccg gatggtagcg tcaacgtacg tcgcttcggc ggcatgaaaa tcgagcgcac
     9901 ctggttcgcc gccgataaga ccggcttcca tatgctgcac acgctgttcc agacctctct
     9961 gcaattcccg cagatccagc gttttgacga acatttcgtg ctggatattc tggttgatga
    10021 tggtcatgtt cgcggcctgg tagcaatgaa catgatggaa ggcacgctgg tgcagatccg
    10081 tgctaacgcg gtcgttatgg ctactggcgg tgcgggtcgc gtttatcgtt acaacaccaa
    10141 cggcggcatc gttaccggtg acggtatggg tatggcgcta agccacggcg ttccgctgcg
    10201 tgacatggaa ttcgttcagt atcacccaac cggtctgcca ggttccggta tcctgatgac
    10261 cgaaggctgc cgcggtgaag gcggtattct ggtcaacaaa aatggctacc gttatctgca
    10321 agattacggc atgggcccgg aaactccgct gggcgagccg aaaaacaaat atatggaact
    10381 gggtccacgc gacaaagttt ctcaggcctt ctggcacgaa tggcgtaaag gcaacaccat
    10441 ctccacgccg cgtggcgatg tggtttatct cgacctgcgt cacctcggcg agaaaaaact
    10501 gcatgaacgt ctgccgttca tctgcgaact ggcgaaagcg tacgttggcg tcgatccggt
    10561 taaagaaccg attccggtac gtccgaccgc acactacacc atgggcggta tcgaaaccga
    10621 tcagaactgt gaaacccgca ttaaaggtct gttcgccgtg ggtgaatgtt cctctgttgg
    10681 tctgcacggt gcaaaccgtc tgggctccaa ctccctggcg gaactggtgg tcttcggccg
    10741 tctggccggt gaacaagcga cagagcgtgc agcaactgcc ggtaatggca acgaagcggc
    10801 aattgaagcg caggcagctg gcgttgaaca acgtctgaaa gatctggtta accaggatgg
    10861 cggcgaaaac tgggcgaaga tccgcgacga aatgggtctg gctatggaag aaggttgcgg
    10921 tatctaccgt acgccggaac tgatgcagaa aaccatcgac aagctggcag agctgcagga
    10981 acgcttcaag cgcgtgcgca tcaccgacac ctccagcgtg ttcaacaccg acctgctcta
    11041 caccattgaa ctgggccacg gtctgaacgt tgctgaatgt atggcgcact ccgcaatggc
    11101 acgtaaagag tcccgcggcg cacaccagcg tctggacgaa ggttgcaccg agcgtgacga
    11161 cgtcaacttc ctcaaacaca ccctcgcctt ccgcgatgct gatggcacga ctcgcctgga
    11221 gtacagcgac gtgaagatta ctacgctgcc gccagctaaa cgcgtttacg gtggcgaagc
    11281 ggatgcagcc gataaggcgg aagcagccaa taagaaggag aaggcgaatg gctgagatga
    11341 aaaacctgaa aattgaggtg gtgcgctata acccggaagt cgataccgca ccgcatagcg
    11401 cattctatga agtgccttat gacgcaacta cctcattact ggatgcgctg ggctacatca
    11461 aagacaacct ggcaccggac ctgagttacc gctggtcctg ccgtatggcg atttgtggtt
    11521 cctgcggcat gatggttaac aacgtgccaa aactggcatg taaaaccttc ctgcgtgatt
    11581 acaccgacgg tatgaaggtt gaagcgttag ctaacttccc gattgaacgc gatctggtgg
    11641 tcgatatgac ccacttcatc gaaagtctgg aagcgatcaa accgtacatc atcggcaact
    11701 cccgcaccgc ggatcagggt actaacatcc agaccccggc gcagatggca aagtatcacc
    11761 agttctccgg ttgcatcaac tgtggtctgt gctacgccgc gtgcccgcag tttggcctga
    11821 acccagagtt catcggtccg gctgccatta cgctggcgca tcgttataac gaagatagcc
    11881 gcgaccacgg taagaaggag cgtatggcgc agttgaacag ccagaacggc gtatggagct
    11941 gtactttcgt gggctattgc tccgaagtct gcccgaaaca cgtcgatccg gctgcggcca
    12001 ttcagcaggg caaagtagaa agttcgaaag actttcttat cgcgaccctg aaaccacgct
    12061 aaggagtgca acatgacgac taaacgtaaa ccgtatgtac ggccaatgac gtccacctgg
    12121 tggaaaaaat tgccgtttta tcgcttttac atgctgcgcg aaggcacggc ggttccggct
    12181 gtgtggttca gcattgaact gattttcggg ctgtttgccc tgaaaaatgg cccggaagcc
    12241 tgggcgggat tcgtcgactt tttacaaaac ccggttatcg tgatcattaa cctgatcact
    12301 ctggcggcag ctctgctgca taccaaaacc tggtttgaac tggcaccgaa agcagccaat
    12361 atcattgtaa aagacgaaaa aatgggacca gagccaatta tcaaaagtct ctgggcggta
    12421 actgtggttg ccaccatcgt aatcctgttt gttgccctgt actggtaagg agcctgagat
    12481 gattaatcca aatccaaagc gttctgacga accggtattc tggggcctct tcggggccgg
    12541 tggtatgtgg agcgcaatta ttgcgccggt gatgatcctg ctggtgggta ttctgctgcc
    12601 actggggctg tttccgggtg atgcgctgag ctacgagcgc gttctggcgt tcgcgcagag
    12661 cttcattggt cgcgtattcc tgttcctgat gatcgttctg ccgctgtggt gtggtttaca
    12721 ccgtatgcac cacgcgatgc acgatctgaa aattcacgtg cctgcgggca aatgggtttt
    12781 ctacggtctg gctgctatct tgacagttgt cacgctgatt ggtatcgtta caatctaacg
    12841 tatcgccaat gtaaatccgg cccgcctatg gcgggccgtt ttgtatggaa accagacctt
    12901 atgttcaaaa cgacgctctg cgccttatta attaccgcct cttgctccac atttgctgcc
    12961 cctcaacaaa tcaacgatat tgtgcatcgc acaattaccc cgcttataga gcaacaaaag
    13021 atccccggta tggcggtggc ggtaatttat cagggtaaac cttattactt tacctggggc
    13081 tatgcggaca tcgccaaaaa gcagcccgtc acacagcaaa cgttgtttga gttaggttcg
    13141 gtcagcaaaa catttacggg cgtgcttggt ggcgacgcta ttgctcgagg ggaaatcaag
    13201 ttaagcgatc ccacaacaaa atactggcct gaacttaccg ctaaacagtg gaatgggatc
    13261 acactattac atctcgcaac ctacactgct ggcggcctgc cattgcaggt gccggatgag
    13321 gtgaaatcct caagcgactt gctgcgcttc tatcaaaact ggcagcctgc atgggcgcca
    13381 ggaacacaac gtctgtatgc caactccagt atcggtttgt tcggcgcact ggctgtgaag
    13441 ccgtctggtt tgagttttga gcaggcgatg caaacacgtg tcttccagcc actcaaactc
    13501 aaccatacgt ggattaatgt accgcccgca gaagaaaaga attacgcctg gggatatcgc
    13561 gaaggcaagg cagttcatgt ttcgccaggg gcgttagatg ctgaaactta tggtgtgaag
    13621 tcgaccattg aagatatggc ctgctgggta cgaagcaata tgaatccccg tgatatcaac
    13681 gacaaaacac ttcagcaagg gatacaactg gcacaatctc gctactggca aaccggcgat
    13741 atgtatcagg gcctgggctg ggaaatgctg gactggccgg taaatcctga cagcatcatt
    13801 aacggcagtg gcaataaaat tgcactggca gcacaccccg taaaagcgat tacgccccca
    13861 actcctgcag tacgcgcatc atgggtacat aaaacagggg caaccggcgg atttggtagc
    13921 tatgtcgcgt ttattccaga aaaagagctg ggtatagtga tgctggctaa caaaaactat
    13981 cccaatccag cgagagtcgc cgccgcctgg cagattctca acgctctaca gtaaaatttc
    14041 atcgggtccg aattttcgga ccttttctgc gcttttcctt gctgtcatct acacttagaa
    14101 aaaaaccagt aaggaaacat ttatgcgcct gctccctctc gttgccgcag cgacagctgc
    14161 atttctggtc gttgcctgca gttctcctac gccgccgcgt ggcgtaacag tagtgaataa
    14221 tttcgacgcc aaacgttatc tcggtacctg gtatgagatt gcccgttttg atcaccgttt
    14281 tgaacgtgga ctggaaaaag tcaccgcaac atacagcctg cgtgatgacg gcggcctgaa
    14341 tgtcattaat aaaggctata accctgacag aggaatgtgg cagcagagtg aagggaaagc
    14401 gtactttacc ggcgcaccaa ctcgcgctgc gctgaaagtg tcattctttg gtcctttcta
    14461 tggcggttat aacgttattg cactcgatcg ggaataccgc catgcgctgg tttgcggccc
    14521 ggaccgcgac tacctgtgga tactctcccg cacgccaacc atttctgacg aagtgaaaca
    14581 ggagatgctg gcagtcgcga cccgggaagg gtttgatgtc agtaagttta tttgggtaca
    14641 gcagcccggt agttagtgag tgctgagttt cagaccaata atccccaata cgattaacgc
    14701 cagactcgcc aggcgcatcg ggttagcgga ctcaccgagc agcacaatgc cggtgatggc
    14761 cgcgccgact gcgccaatac ccgtccacac ggcataagcc gtccctaccg gtaacgattt
    14821 catcgcccag gcaagtagcg ccatactgac tatcatcgcc gtcacagtaa taacacttgg
    14881 cgtcaaacga ctaaagccgt gggtatattt caggccaacg gcccatacca cttccagcag
    14941 accagcaata actaagataa tccaggacat atcaggctcc ggagaattgg ggccgtcccc
    15001 ggtgaaaaga ggcgtttgca ggtcgtcctg caaagctgat ggttgaacgg atattttgcc
    15061 aggtggcagg ggaatttcaa ctattacctt tgtgactatc gcaaaaaaac aaacggcacg
    15121 acataactgt cgtaccgtta ttgcttattg ctgcgctttc gttgctgcac cagaaatcgc
    15181 gttaccgcca tcagaaatgt cttcaccaac gccacgcgtg gtgttgcagg cagttaatac
    15241 tgttgaaagc accagaacag aaaagatcgc tgcaattgtc ttcttcacca taacgtcttc
    15301 cttttaggta atgttattta tgtttgccta tagcaaatta ataatagaca acatcgccaa
    15361 aaatgatgga aatctgatga tttttcggaa gagaagaaaa attagctggc agcgcgagag
    15421 atggagttgc cgagatgttt gatgtcttcg ccgaaaccgc gagcggtgtt acagcccgtg
    15481 agcagcgtgc tggcaagcaa aacaagaacg ataaggcgtt tcatcatctc tgacctgaat
    15541 aagtgatggt gcagcctgca ggccgcacca caaccgcatt acttcacgcg agagacgtat
    15601 tcaccagagc gggtatccac tttgatgact tcgccgattt gtacgaacag cggaacttta
    15661 accacagcgc cagtagacag ggtagccggt ttgccgccag tacctgcggt atcacctttc
    15721 aggcccggat cggtatcaac gatttccagt tcaacgaagt tcggcggagt aacggagatc
    15781 ggctgaccat tccacagagt tacgatacac tctgcctgat ccagcagcca tttagcgttg
    15841 tcgccaattg cttttgcatc agcagacagc tgctcgaaag tttcgttgtt catgaagtgc
    15901 cagaactcac cgtcgttgta caggtaagtc aggttcatat cgacaacatc agcgccttca
    15961 gcggaatcag tagatttgaa ggttttttct acgcgagtac cggtcagcag acgacgcagt
    16021 ttaacgcgag caaatgcctg gcctttaccc ggttttacga attcactcgc ttcaaccgcg
    16081 taaggttcgc cgtctaacat gattttaaga ccagcacgaa aatcgttgct atagtacgtt
    16141 gccataaggc cctctgaaat ttgttaattg gtagctaagc cacaaaatgg cgcatattgt
    16201 aaccctaaat accccatcca gagaagattg gttaacgcaa cttgccgatg ttgtgaccga
    16261 tcctgatgaa cttctgcgtc ttttgaatat agacgcggac gaaaaactgt tggccggacg
    16321 cagcgccaaa aagctgtttg ccctgcgtgt gccccgctca tttatcgatc gcatggagaa
    16381 aggcaatccg gacgatcctc ttttgcgtca ggtacttacc tcgcaagatg agtttgtcgt
    16441 cgcgtccgga ttctccaccg acccgctgga agaacagcac agcgtagtgc ctggtttgtt
    16501 gcataaatac cacaaccggg cgcttttgct ggtcaaaggc ggctgcgcgg taaattgccg
    16561 ctattgcttc cgtcgccact tcccctatgc cgaaaatcag ggcaacaagc gtaactggca
    16621 gactgctctt gagtatgttg ctgcgcatcc ggaactggac gagatgattt tctccggcgg
    16681 cgatccgctg atggcgaaag atcacgagct ggactggttg ctcacacaac tggaagccat
    16741 cccgcatatc aaacgtctgc ggattcacag ccgtctgccg attgtgatcc cggcacgtat
    16801 caccgaggcg ctggttgaac gctttgcccg ttctacgctg caaatcttgc tggtgaatca
    16861 catcaatcat gccaatgagg tagatgaaac gttccgtcag gcgatggcta aattgcgccg
    16921 tgtcggtgtc accctgctta accagagcgt tctgttacgt ggtgtgaacg ataacgcaca
    16981 aacgctggca aacctgagta atgcgttgtt cgatgccggc gtgatgccgt attacctgca
    17041 tgtgctagat aaagtacagg gcgcggcgca ttttatggtg agtgatgacg aagcacggca
    17101 gattatgcgt gagttgctga cactggtgtc gggttatctg gtgccgaaac tggcgcgaga
    17161 aatcggcggc gaacccagca aaacgccgct ggatctccag ctacgccagc agtaactgat
    17221 taaacaggga agttaaacat tagcctgatg cgctacgctt atcaggccta cattgtgcat
    17281 tgaaattgaa tggatttgca atgaactgta ggccggataa ggcgtttacg ccgcatccgg
    17341 caagagcaac aaacgcaagt acagcaacct gtcattaaac tgggaaattt aatctttgcc
    17401 cgttgcataa cctttaatta ttcatataca ttgctgttgt tactctttat atagccaaca
    17461 ccaataatta acctttcttt tctgtttata tagagtgagt acggc
//
LOCUS       DAPGUL010000379        12950 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.guided.131, whole genome shotgun sequence.
ACCESSION   DAPGUL010000379 DAPGUL010000000
VERSION     DAPGUL010000379.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12950)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12950)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12950
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.guided.131"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            51..824
                     /locus_tag="RHX21_005038"
     CDS             51..824
                     /locus_tag="RHX21_005038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308281.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDV1990054.1"
                     /translation="MHDQPLLSMSLPSIPSFVLSGLLLLCLPFSSFASATTSHITFSY
                     AARQRMQNRARLLKQYQTHLKKQASYIVEGNAESRRALRQHNREQIKQHPEWFPAPLK
                     ASDRRWQALAENNHFLSSDHLHNITEVAIHRLEQQLGKPYVWGGTRPDQGFDCSGLVF
                     YAYNKILEAKLPRTANEMYHYHRATIVANNDLRRGDLLFFHIHSREIADHMGVYLGDG
                     QFIESPRTGETIRVSRLAEPFWQDHFLGARRILTEETIL"
     gene            complement(881..1237)
                     /locus_tag="RHX21_005039"
     CDS             complement(881..1237)
                     /locus_tag="RHX21_005039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HDV1990055.1"
                     /translation="MNKASNIITIKGQPAAVTFEADINAFRGKFLNVNGYCDFVATSI
                     EALYREGESALDEWMADCEEDGIAPFREEEEQKRLTLRVPHHIDSRLTIVARQHSISK
                     NQLIVDVLEREFSAHM"
     gene            complement(1230..1508)
                     /locus_tag="RHX21_005040"
     CDS             complement(1230..1508)
                     /locus_tag="RHX21_005040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000598761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HDV1990056.1"
                     /translation="MIKVSALGSRHRKTFDDVMTEPPKSGIKWDDVVALIKAVGGTIK
                     NNNGSRRKFQIGTTKFSTHEPHPKNVMDKGAVAGLKEWFVNCVGGDYE"
     gene            complement(1613..3325)
                     /locus_tag="RHX21_005041"
                     /pseudo
     CDS             complement(1613..3325)
                     /locus_tag="RHX21_005041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
     gene            3297..4082
                     /gene="lafU"
                     /locus_tag="RHX21_005042"
     CDS             3297..4082
                     /gene="lafU"
                     /locus_tag="RHX21_005042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706230.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative lateral flagellar export/assembly
                     protein LafU"
                     /protein_id="HDV1990057.1"
                     /translation="MTTIKLIVNSVSKSERESIIAALHGQSIFNGGGLSPLNKISPSH
                     PPKPATVAVPEETEKKARDVNEKTVLLKKKSATELGELATSINTIARDAHMEANLEME
                     IVPQGLRVLIKDDQNRNMFERGSAQIMPFFKRLLVELAPVFDSLDNKIIITGHTDAMA
                     YKNNIYNNWNLSGDRALSARRVLEEAGMPEDKVMQVSAMADQMLLDSKNPQSAGNRRI
                     EIMVLTKSASDTLYQYFGQHGDKVVQPLVQKLDKQQVLSQRTR"
     gene            4153..5208
                     /gene="dinB"
                     /locus_tag="RHX21_005043"
     CDS             4153..5208
                     /gene="dinB"
                     /locus_tag="RHX21_005043"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HDV1990058.1"
                     /translation="MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTA
                     NYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSL
                     DEAYLDVTDSVHCHGSATLIAQEIRQTIFSELQLTASAGVAPVKFLAKIASDMNKPNG
                     QFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVMLLKRFGKF
                     GRILWERSQGIDERDVNSERLRKSVGVERTMAEDIHHWSECEAIIERLYPELERRLAK
                     VKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATARKTWDERRGGRGVRLVGL
                     HVTLLDPQMERQLVLGL"
     gene            5205..5657
                     /locus_tag="RHX21_005044"
     CDS             5205..5657
                     /locus_tag="RHX21_005044"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDV1990059.1"
                     /translation="MNNIQIRDYQPGDFQQLCAIFIRAVTMTASQHYSPQQIAAWAQI
                     DESRWKEKLAKSQVRVAVINAKLVGFITCVEHYIDMLFVDPEYTRRGVASALLKPLIK
                     SESELTVDASITAKPFFERYGFQTVKQQRVECRGEWFINFYMRYKQQH"
     gene            5903..7042
                     /locus_tag="RHX21_005045"
     CDS             5903..7042
                     /locus_tag="RHX21_005045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HDV1990060.1"
                     /translation="MGNYIRPLSDAVFTIASDDLWIESLAIQQLHTTANLPNMQRVVG
                     MPDLHPGRGYPIGAAFFSVGRFYPALVGNDIGCGMALWQTDILTRKYNADKFEKRLSD
                     LDDVAEESWLEENLPSAFAQHPWRSSLGSIGGGNHFAELQQVDQIINAELFALAGLDA
                     QHLQLLVHSGSRGVGQSILQRHIASFSHHGLPQGSDDALRYIAEHDDALAFACINRQM
                     IALRIMQQVKATGSPVLDVAHNFVSACQIGDQQGWLHRKGATPDDNGLVIIPGSRGDY
                     SWIVQPVANEKTLHSLAHGAGRKWGRTECKGRLAAKYTATQLSRTELGSRVICRDKQL
                     IFEEAPQAYKSAESVVQCLVQAGLIIPVARLRPVLTLKNSGGKKG"
     gene            7039..7653
                     /locus_tag="RHX21_005046"
     CDS             7039..7653
                     /locus_tag="RHX21_005046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor H"
                     /protein_id="HDV1990061.1"
                     /translation="MILLQLSSAQGPEECCLAVKKALDRLIKEAARQDVAVTVLETET
                     GRYSDTLRSALVSLDGDNAWALSESWCGTIQWICPSPYRPHHGRKNWFLGIGRFTADE
                     QEQSDAIRYETLRSSGPGGQHVNKTDSAVRATHLASGISVKVQSERSQHANKRLARLL
                     IAWKLEQQQQENSAVLKSQRRMFHHQIERGNPRRTFTGMAFIEG"
     gene            complement(7710..9167)
                     /gene="pepD"
                     /locus_tag="RHX21_005047"
     CDS             complement(7710..9167)
                     /gene="pepD"
                     /locus_tag="RHX21_005047"
                     /EC_number="3.4.13.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosol nonspecific dipeptidase"
                     /protein_id="HDV1990062.1"
                     /translation="MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKG
                     FHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDG
                     EWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQSNWL
                     QADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFKLTLKGLKGGHSGG
                     EIHVGLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDVL
                     KSLVNTYQEILKNELAEKEKNLALLLDSVANDKAALIAKSRDTFIRLLNATPNGVIRN
                     SDVAKGVVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEA
                     KGAYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIG
                     PTITGPHSPDEQVHIESVGHYWTLLTELLKEIPAK"
     gene            9428..9886
                     /gene="gpt"
                     /locus_tag="RHX21_005048"
     CDS             9428..9886
                     /gene="gpt"
                     /locus_tag="RHX21_005048"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HDV1990063.1"
                     /translation="MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR"
     gene            9978..11222
                     /gene="frsA"
                     /locus_tag="RHX21_005049"
     CDS             9978..11222
                     /gene="frsA"
                     /locus_tag="RHX21_005049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase FrsA"
                     /protein_id="HDV1990064.1"
                     /translation="MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTI
                     PHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWA
                     TQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEA
                     AQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYF
                     APRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGA
                     NVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEA
                     LRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFN
                     PVYRNFDKGLQEITGWIEKRLC"
     gene            11280..11681
                     /gene="crl"
                     /locus_tag="RHX21_005050"
     CDS             11280..11681
                     /gene="crl"
                     /locus_tag="RHX21_005050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-binding protein Crl"
                     /protein_id="HDV1990065.1"
                     /translation="MTLPSGHPKSRLIKKFTALGPYIREGKCEDNRFFFDCLAVCVNV
                     KPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWKSVPVKDTEVVERLEHTLRE
                     FHEKLRELLTTLNLKLEPADDFRDEPVKLTA"
     gene            complement(11720..12775)
                     /gene="phoE"
                     /locus_tag="RHX21_005051"
     CDS             complement(11720..12775)
                     /gene="phoE"
                     /locus_tag="RHX21_005051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoporin PhoE"
                     /protein_id="HDV1990066.1"
                     /translation="MKKSTLALVVMGIVASASVQAAEIYNKDGNKLDVYGKVKAMHYM
                     SDNDSKDGDQSYIRFGFKGETQINDQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGL
                     KYKDLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFF
                     GVIDGLNLTLQYQGKNENRDVKKQNGDGFGTSLTYDFGGSDFAISGAYTNSDRTNEQN
                     LQSRGTGKRAEAWATGLKYDANNIYLATFYSETRKMTPITGGFANKTQNFEAVAQYQF
                     DFGLRPSLGYVLSKGKDIEGIGGEDLVNYIDVGATYYFNKNMSAFVDYKINQLDSDNK
                     LNINNDDIVAIGMTYQF"
BASE COUNT         3141 a         3263 c         3330 g         3216 t
ORIGIN      
        1 atggtttatt aagtttgttc aggtacgggc cgggatacac tgcaacatca atgcatgatc
       61 agccattatt gagtatgtcc ttgccgtcga ttccctcttt tgtgttgtcg ggattactgt
      121 tgctttgctt gccgttttct tcatttgcca gcgccaccac atcacatatc actttcagct
      181 acgccgcccg ccagcggatg caaaatcgtg cgcgtttatt aaaacagtac caaacccatc
      241 tgaaaaaaca ggccagctat attgtggaag gcaatgccga aagcagaagg gcgctacgcc
      301 agcacaaccg cgaacagata aaacagcatc cagaatggtt tcctgcgccg ctcaaggcga
      361 gtgacagacg ctggcaggcg ctggcggaaa acaaccattt cttaagcagc gaccatctgc
      421 ataacatcac cgaagtagcg attcaccgtc tggagcaaca gcttggcaag ccttacgtat
      481 ggggcggcac gcggcccgat caaggcttcg actgtagcgg gttggttttc tatgcctaca
      541 acaagatcct tgaggcgaag ctcccacgca cggccaacga gatgtatcac taccatcggg
      601 caacgattgt ggcgaataac gacctgcgcc ggggagattt gctgtttttc catatccaca
      661 gccgcgagat tgccgatcat atgggggtgt atctgggcga tggccagttt atcgagtcgc
      721 cgcgcaccgg ggaaaccatt cgggtaagcc ggttagccga acctttctgg caggaccatt
      781 ttttgggcgc gcgcaggatt ttgacggaag agacgatttt gtaaatgggt aatattgacg
      841 aactggcaaa aggccggatg ccacgcggca tccgacttgt ttacatatgg gctgaaaact
      901 cacgttctaa gacatcaaca atgagctggt tttttgaaat ggaatgttgt ctggcgacga
      961 tggtcagccg cgaatcaatg tgatgaggaa cacgaagcgt caggcgtttt tgctcttctt
     1021 cttcacgaaa aggggcaata ccgtcctctt cacaatccgc catccactca tccagcgcgc
     1081 tttcgccctc acgatataat gcctcaatgc ttgtggctac aaagtcacaa taaccgttta
     1141 cattgaggaa cttgccgcga aatgcgttga tatcggcttc aaatgtcact gcggctggtt
     1201 gacctttaat tgtgataatg ttcgatgctt tattcataat ctccccctac acagttaaca
     1261 aaccactcct taagacctgc tactgcacct ttatccatca cattctttgg atgtggctca
     1321 tgtgtactga atttggtcgt tccaatctga aatttccttc tggacccatt gttatttttt
     1381 attgttccac ccaccgcttt aatgagcgca acaacatcat cccatttaat tccagatttt
     1441 ggcggctccg tcattacatc gtcgaatgtt tttctatggc gggagcctag cgcgctgacc
     1501 ttaatcatac tatcaatcca tgacgtcatt gtatggtgtc atcgtagtat gtttgcaatg
     1561 tgacgtcaat caatggtgtc agatgcatgc aaagcatgga aaagaatcct catcaactca
     1621 acgctcccat aatcttcaac tccagctcat ccggcacttc attatacgac agcacatgca
     1681 gccccggcgc aaacaacctc gcatagcgtg ccagcaaagg gcgcaactgc ggcggcacca
     1741 gcagcaccgg gtctttcccc gccgctttca tctgctcctt cacctgcggc atcgtactct
     1801 ggaactggtt gagcatattc ggatcgaccg gcacgctgtc gagcatcact ttcccgccct
     1861 gttgcgcctg attcaccacg ttggtcagca gattttccag ctcattattc agggtataca
     1921 ccgtcagctc ctgcttgcga acgaacggat gggtaatgct gcgccgcagc gccaggcgca
     1981 catcagctgc cagcagaata tgatctttgg tcaccgcgct actggcgacc agcacggtgg
     2041 caatggtgac gatatcgcgc agggaaacgc cttcggtcag cagcgcgcgg tacactttca
     2101 gcaactggct gtaattcagc gccgcgctta aatcttccgc caggcgcggt gccatcgacg
     2161 acaaacggtt atgcaactgc gtaatatcgt catagttaaa taaatcagga atatagctac
     2221 gcacaatctt attcacatgc gtggcaatca cgctggcgct gtcgatcacc tgatacccca
     2281 tattcagcgc cttcgctttc tgcgcgggct ggatccaggt caccggcatc ccgtacgccg
     2341 ggtcgttccc cagcacgccg tcaatttcgc cgtaggtttc gctggagggt agggccatca
     2401 gtttatccgc cggaatatcc gcttcatcag ccttaatgcc gttgatgaaa atagcgtact
     2461 ggctgggctt gaggcggaag ttttcccgaa tacggatctc cggcagcagc acgccgttac
     2521 cgtcggatat cacctgccgc acgccgcgaa tccgctgggt gagcgggttg ccctgcgctt
     2581 tatccaccag cgccaccagc ttgtagccga ggcttaagct gatgggctcg atcagcggaa
     2641 tggtttccca actgacctgt tgctcgctgg tttcggtgat ggtgcgggtc agcgtttcga
     2701 gacttttctc ttccgcttcc gccgcctgcg ggcgtttgct catccgccag ccggtaaagc
     2761 caagcagggc gctgaacagc aaaaacggca gatgtggcat tcccggcact accgccagta
     2821 cgaacataat tccggtagcg gtgtagagca ccgacgggct tgccagcaac tggttacgca
     2881 cgtcatgggc gatatcgccg ttgtcgctga cgcgggtgac gataatcgcc gccgcggtgg
     2941 agagtagcag ggaagggatt tgcgccacca gcccgtcgcc gatggtcatc agcacatact
     3001 gctggaaggc ggcgtcggcg ctcaggttgt atttgaagat cccgatacag acgccgccga
     3061 tcaggttgat cgccagaatc atcatcccgg cgatagcatc cccgcgcaca aatttcgatg
     3121 ccccgtccat cgcgccgtag aaatcggcct cgctggcaac atctttacgt cgggtttgtg
     3181 cctgcgcctg attgatcaac ccggcattaa gatcggcgtc aatcgccatc tgcttaccgg
     3241 gcatcgcatc cagggtaaag cgggctgaaa cctcggaaat acgctcggcc cctttggtga
     3301 cgacaataaa gttgattgtc aacagcgtca gtaaatccga gcgtgaaagc attatcgccg
     3361 cgctgcacgg gcagtcgatt tttaacggtg gtgggctgtc gccgttaaat aaaatcagcc
     3421 cgtctcatcc gccaaaacct gccaccgtgg cggtgccgga agagacggag aaaaaagcgc
     3481 gtgacgtcaa tgagaaaacg gtgctgctga agaagaaatc cgccaccgag cttggcgagc
     3541 tggcaaccag tatcaacacc attgcccgtg atgcgcatat ggaagcgaat ctggagatgg
     3601 agattgtccc gcagggatta cgcgtgctga ttaaagacga ccagaatcgc aatatgttcg
     3661 aacgcggcag cgcgcagatt atgccgttct ttaaaaggct gctggtggag ctcgcgccag
     3721 ttttcgactc gctcgataac aaaattatta ttaccgggca taccgatgcg atggcctaca
     3781 aaaacaatat ctacaacaac tggaaccttt cgggcgatcg cgcgctttca gctcgtcggg
     3841 tgctggaaga ggccggaatg ccggaagata aagtgatgca ggtaagcgca atggcggacc
     3901 agatgctgct ggattccaaa aatccgcaaa gcgcgggcaa ccggcgcatt gagattatgg
     3961 tgctgaccaa aagtgcgtcc gatacgctgt atcaatactt tggtcagcat ggggataaag
     4021 tggtgcagcc gctggtgcaa aagctggata agcagcaggt gctttcgcag cgaacgcgtt
     4081 aaatgctgaa tctttacgca tttctcaaac cctgaaatca ctgtatactt taccagtgtt
     4141 gagaggtgag taatgcgtaa aatcattcat gtggatatgg actgcttttt cgcagcggtg
     4201 gagatgcgcg acaatcccgc cctgcgcgat atccctattg ctattggcgg cagccgcgaa
     4261 cgtcgggggg tgatcagcac cgccaattat cccgcgcgta aatttggcgt acgtagcgct
     4321 atgccgacag ggatggcgct caaattatgc ccgcatctca ccttgcttcc ggggcgcttt
     4381 gacgcctaca aagaagcctc aaatcatatc cgtgaaatct tctcgcgcta cacctcgcgt
     4441 attgaaccgt tgtcactgga tgaggcttat ctcgacgtca ccgatagcgt ccattgccac
     4501 ggttctgcga ccctcatcgc ccaggaaatc cgccagacga ttttcagcga gctgcaactg
     4561 acggcgtctg cgggcgtggc accagtaaag tttctcgcca aaatcgcctc cgacatgaat
     4621 aaacccaacg gtcagtttgt gattacgccg gcagaagttc cggcattttt acaaacctta
     4681 ccgctggcaa aaatccccgg cgtcggcaaa gtctcggcgg caaaactgga agcgatgggg
     4741 ctgcggacct gcggtgatgt acaaaagtgt gatctggtga tgctgcttaa acgctttggc
     4801 aaatttggcc gcattttgtg ggagcgtagt caggggattg acgagcgcga cgttaacagc
     4861 gaacggttgc gaaaatccgt cggcgtggaa cgcacgatgg cggaagatat ccaccactgg
     4921 tctgaatgtg aagcgattat cgagcggctg tatccggaac ttgaacgccg tctggcaaag
     4981 gtaaaacctg atttactgat tgcccgccag ggggtgaaat taaagttcga cgattttcag
     5041 caaaccactc aggagcacgt ctggccgcgg ctgaataaag ctgacttaat cgccaccgcg
     5101 cgtaaaacct gggatgaacg ccgcggcggg cgcggtgtgc gactggtggg gctgcatgtg
     5161 acgttgcttg acccgcaaat ggaaagacaa ctggtgctgg gattatgaat aacatacaaa
     5221 taagagacta tcagcctggc gattttcagc aactatgcgc tattttcatt agagcggtta
     5281 cgatgactgc cagtcagcat tattcaccac aacaaattgc cgcctgggcg cagattgacg
     5341 aatctcgctg gaaggagaaa ctcgcgaaat cacaagtgcg ggttgcagtc attaatgcaa
     5401 aactggtcgg ctttattacc tgcgttgaac actatatcga tatgttattt gttgaccctg
     5461 aatacacccg ccgtggggtt gccagcgctt tgttaaaacc tttgattaag tctgaatccg
     5521 aacttacggt ggacgcaagc ataaccgcaa aacccttttt tgaacgttat ggttttcaga
     5581 cagttaagca gcaacgcgtt gaatgtcggg gagagtggtt tattaatttt tatatgcgtt
     5641 ataaacagca acattaaatc cagcttgcaa tgaaaataac gcaagcctag tatgtgcgcg
     5701 ttttcttatt ccacaaactg caaggaggta aatcatgaca aatcctttat caatgactct
     5761 ttgcagacct ttccaggatt aattcttttt ttcttgccct ggattcgtct gccatttcct
     5821 gattttttaa ttgttactct caataattca agtcgcaaca catgcaactt gaagtatgac
     5881 gagtctattt acggaatggt atatgggcaa ttatattcgt cccttatccg atgcggtatt
     5941 taccatcgca tctgatgacc tgtggatcga gagtttagcg atccaacaat tacacaccac
     6001 ggcaaattta cccaacatgc agcgcgtagt ggggatgcca gatttacatc ccggacgcgg
     6061 ctatccgatt ggcgcagcgt tcttctctgt tggtcgtttt tatccggcac tggtcggcaa
     6121 tgatatcggc tgcggtatgg cgctatggca aacagatatt ctcactcgca aatacaacgc
     6181 cgataagttt gaaaagcgat tatcagatct ggatgacgtt gctgaagaaa gctggctgga
     6241 ggaaaacctg ccgtcagcat ttgcacagca tccgtggcgc agctcgcttg gctctatcgg
     6301 tggcggcaat catttcgctg aactgcaaca agttgatcaa atcatcaacg ctgaactgtt
     6361 tgcactggca ggtctggatg cacaacatct gcaactgttg gttcatagcg gctcgcgggg
     6421 ggtggggcag tctattttac agcggcatat tgcctcgttc tcgcatcatg gtttgcctca
     6481 aggcagtgac gacgcgctac ggtatattgc ggaacatgac gatgcgctgg cgtttgcgtg
     6541 tattaatcgc cagatgatcg ctttgcgcat aatgcaacaa gttaaggcca cgggaagtcc
     6601 ggttctggat gtggcgcata actttgttag cgcgtgtcaa atcggcgatc aacagggctg
     6661 gttgcatcgt aaaggtgcca cgccggatga caacggtctg gtgattattc ccggttcacg
     6721 tggtgattac tcctggattg tacagcctgt tgcgaacgaa aaaacgctcc actcgctggc
     6781 gcatggggca gggcgtaaat gggggcgcac cgagtgtaaa gggcgtctgg cagcgaaata
     6841 cacggcgacg caactctcgc gtactgaact tggcagtcgg gtaatttgtc gcgataaaca
     6901 actcatcttt gaagaagcgc cacaagccta taaatcggct gaaagcgtgg tgcaatgtct
     6961 ggtgcaggcc ggtttaatta ttcctgtcgc gcggctgcgt ccggtgctaa cgctcaaaaa
     7021 cagtggaggg aaaaaaggat gatcttgcta caactctcct cagcgcaggg gccggaagaa
     7081 tgttgtctcg cagtgaaaaa ggcgctggac aggctaatta aagaagctgc ccgacaagac
     7141 gtcgcggtaa cggtgttgga aacagaaacg ggccgctact ctgacacgct gcgttcagct
     7201 ctggtttctc tggatggcga taacgcatgg gcattaagcg aaagctggtg cggcactatt
     7261 cagtggattt gtccgagtcc gtatcggcct catcatgggc gcaaaaactg gtttctgggc
     7321 attgggcgtt ttaccgctga tgagcaggaa caatcggatg caatccgtta tgagacgttg
     7381 cgttcgtcgg ggccgggcgg tcaacatgtc aataaaaccg actcggcggt acgcgccacg
     7441 catttggcat ccggtattag cgtgaaggtt cagtcagagc gtagtcagca tgctaacaag
     7501 cggctggcac gattgctgat tgcctggaag ctggagcagc agcaacagga aaatagcgcg
     7561 gtgctgaaat cgcagcggcg aatgttccat caccagattg aacgtggcaa cccgagacgg
     7621 acatttacag ggatggcttt tatcgaagga taatgaagga tgaaactgcc ggaaggcgat
     7681 taaacgccat ccggcagcaa atcaaataat tacttcgccg gaatttcttt cagcagttca
     7741 gtcagcagtg tccagtaatg acctacgctt tcgatgtgaa cttgctcatc cggagagtgt
     7801 ggaccggtga tagttggccc gatagaaacc atgtccattt ccggatacgg ttttttgaac
     7861 agaccacatt ccaggcccgc gtggataatc tggatgttcg gtgttttgtt gaacagacgc
     7921 tgataggttt cacgtaccag atgcatcacc ggagaattag cgtccggctg ccagccagga
     7981 tatgcgcctt tcgcttcggt tttcgcgcca gctagtttac ccagcgaatc cagcatgctc
     8041 accacgtagt ctttaccgct gtcgatcagt gaacggatca ggcagtgaat ttctacgtta
     8101 ttgtcagtca tggtcaccac accgacgttc agggaggttt cgaccacacc ttttgccacg
     8161 tcggaattgc ggatcacacc gttcggggtg gcgttcagca gacgaataaa ggtatcgcga
     8221 gatttcgcaa tcagggcagc tttatcgttc gctacagagt ccagcaacaa ggccagattt
     8281 ttctctttct ctgccagctc gtttttcagg atctcctgat aggtattcac cagagatttc
     8341 aggacgtcga ctttatcagc tgcgacagca atggtcgcaa aggcttcacg cgggatggcg
     8401 ttacgcagtg tgccgccgtt gaaatcgata aggcgcagat ccagttcttc cgcatgaccc
     8461 gccaggaagc gcaccagtag tttgttggca ttacccaggc caacgtggat ttcaccgccg
     8521 gagtgaccgc ctttcagacc ttttaaggtt aacttgaagg tttcaaaacc agctggaacc
     8581 gcttcacgat ctaaatgcag gttggaggtg aagtcgatac cccccgcaca acccatgtag
     8641 atttcacctt cttcttcgga gtcggtgtta atcagaatat cagcctgcaa ccagttgctc
     8701 tgtaagccga acgcaccgtc cataccggct tcttcggtca tggtcagcag cacttccagc
     8761 gggccgtgaa ccacgttttc gtcagccaga accgccagcg cagacgccat accaatgccg
     8821 ttatctgcac ccagcgtggt gccgcgcgct ttaacccatt cgccatcaat ataaggctgg
     8881 ataggatctt tcgtgaagtc atgcacggtg tcgttatttt tctgcggcac catatcgagg
     8941 tgggcctgta agacgaccgg tttacgattt tccatacctg cggtagcagg tttacgaatc
     9001 aggatattac ctacctgatc gcgttcgaca tggaaacctt tctcttttgc ccaaccaaca
     9061 atgtattcag cgagttgctc ttcatgatag gacgggtgag gaatagaaca gattttggca
     9121 aaaatatccc acagcggctg tggagataat tgagacagtt cagacacgtt aagtctcctt
     9181 gtcgatcacc cgcaaaacag tattgcaggt cacagggtta gcagaaaatg ttgtcaacac
     9241 aagacaggct tgcgagatat gtttgagaat accactttat cccgcgtcag ggagaggcag
     9301 tgcgtaaaaa gacgcggact catgtgaaat actggttttt agtgcgccag atctctataa
     9361 tctcgcgcaa cctattttcc cctcgaacac tttttaagcc gtagataaac aggctgggac
     9421 acttcacatg agcgaaaaat acatcgtcac ctgggacatg ttgcagatcc atgcacgtaa
     9481 actcgcaagc cgactgatgc cttctgaaca atggaaaggc attattgccg taagccgtgg
     9541 cggtctggta ccgggtgcgt tactggcgcg tgaactgggt attcgtcatg tcgataccgt
     9601 ttgtatttcc agctacgatc acgacaacca gcgcgagctt aaagtgctga aacgcgcaga
     9661 aggcgatggc gaaggcttca tcgttattga tgacctggtg gataccggtg gtactgcggt
     9721 tgcgattcgt gaaatgtatc caaaagcgca ctttgtcacc atctttgcaa aaccggctgg
     9781 tcgtccgctg gttgatgatt atgttgttga tatcccgcaa gatacctgga tcgaacagcc
     9841 gtgggatatg ggcgtcgtat tcgtcccgcc aatctccggt cgctaatctt ttcaacgcct
     9901 ggcactgccg ggcgttgttc tttttaactt caggcgggtt acaatagttt ccagtaagta
     9961 ttctggaggc tgcatccatg acacaggcaa acctgagcga aaccctgttc aaaccccgct
    10021 ttaaacatcc tgaaacctcg acgctagtcc gccgctttaa tcacggcgca caaccgcctg
    10081 tgcagtcggc tcttgatggt aaaaccatcc ctcactggta tcgcatgatt aaccgtctga
    10141 tgtggatctg gcgcggtatt gacccacgtg aaatcctaga cgtccaggca cgtattgtga
    10201 tgagcgatgc tgaacgtacc gacgatgatt tatacgatac tgtgattggc taccgtggtg
    10261 gcaactggat ttatgagtgg gccacccagg cgatggtgtg gcaacaaaaa gcctgtgcgg
    10321 aagaagatcc gcaactcagt ggtcgacact ggctgcatgc ggctacgttg tacaacattg
    10381 ccgcctatcc tcatctgaaa ggagatgacc tggccgagca agcgcaggct ttatcaaacc
    10441 gcgcctatga agaggccgcc cagcgtctgc cgggcacgat gcggcagatg gagtttactg
    10501 tacccggcgg tgcgcccatc accggctttt tgcatatgcc gaaaggcgat ggcccgttcc
    10561 cgacagtatt aatgtgtggt ggtctggatg cgatgcagac ggactattac agcctgtatg
    10621 aacgttattt tgcgccgcgc ggcattgcga tgctgactat tgatatgccg tcggtgggct
    10681 tttcttcaaa atggaagctc acccaggact ccagcctgtt gcatcagcac gtcttaaagg
    10741 cgctgcctaa cgtaccgtgg gtggatcaca ctcgcgtcgc ggcctttggt ttccgtttcg
    10801 gcgctaacgt tgccgtgcgt ctggcatacc ttgaatcgcc gcgtctgaaa gcggttgcct
    10861 gtcttggtcc ggtagttcat accctgttga gtgattttaa gtgccagcaa caggtgccgg
    10921 aaatgtatct tgacgttctg gcgagtcgtt tggggatgca tgatgcttcc gacgaagcgt
    10981 tacgcgtgga gctgaatcgc tattcattaa aagtgcaagg attgctggga cgtcgctgcc
    11041 caacgccaat gttatcaggc tactggaaga acgatccgtt cagcccggaa gaggactcac
    11101 gcttaatcac ctcatcatct gctgacggta aattattaga gatcccattt aacccggtgt
    11161 atcggaattt tgacaaaggt cttcaggaaa tcaccggctg gatcgaaaaa cgcttgtgtt
    11221 aaaaatttgc taaattttgc caatttggta aaacagttgc atcacaacag gagatagcaa
    11281 tgacgttacc gagtggacac ccgaagagca gattgatcaa aaaatttacc gcactaggcc
    11341 cgtatattcg tgaaggtaag tgcgaagata atcgattctt tttcgattgt ctggctgtat
    11401 gcgtcaacgt gaaaccggca ccggaagtgc gtgaattctg gggctggtgg atggagctgg
    11461 aagcgcagga atcccgtttt acctacagct accagtttgg tctgttcgat aaagcaggcg
    11521 actggaagag tgttccggta aaagatactg aagtggttga acgactggag cacaccctgc
    11581 gtgagtttca cgagaagctg cgtgaactgc tgacgacgct gaatctgaag ctggaaccgg
    11641 cggatgattt tcgtgacgag ccggtgaagt taacggcgtg agtgaaatgt gccggatgca
    11701 tcacatccgg caatatctat taaaactgat acgtcatccc aatcgcgaca atatcatcat
    11761 tattaatatt caatttgtta tcgctatcca gttggttgat tttataatca acaaatgctg
    11821 acatattttt gttgaaataa tacgtagcac cgacgtcgat ataattaacc agatcttcac
    11881 caccgatacc ttcaatatct ttccctttcg ataagacata acccagcgat ggacgcagac
    11941 caaagtcaaa ctggtattga gcgaccgctt caaagttctg tgtcttattg gcaaagccgc
    12001 cagttattgg cgtcattttg cgtgtttcag aataaaaagt tgccagataa atattattgg
    12061 catcgtattt cagacctgta gcccatgctt ctgcacgctt gcctgtgcca cggctttgca
    12121 ggttctgctc gttggtgcga tctgagttgg tataggcccc actaatggcg aaatcgctgc
    12181 cgccaaagtc atatgtcaat gacgtgccga agccatcgcc gttttgcttt ttaacgtcgc
    12241 ggttttcgtt tttcccttga tattgcaggg ttaagttcag gccatcgata acgccgaaga
    12301 agtcggtgtt ccgatacgtc gccagaccgc tggcgcgttt ggtcataaag ttgtcggtct
    12361 gcgccgagga gtcgccacca aattccggga acatatcggt ccaggcttcc acgtcataca
    12421 acgcgcccag gttacggcca tagtcgaaag aacccaaatc tttatacttc aatccggcaa
    12481 aagcgagacg cgttttttgc tgtgcagtat cactctccgc tttatttccg gcaaactccg
    12541 cttcccaacg gccatagcca gtcagttgat cgttaatttg tgtttcgcct ttaaaaccaa
    12601 aacggatata actctggtcg ccatctttac tgtcgttatc actcatataa tgcatggctt
    12661 taactttgcc atagacatcc agtttattac cgtctttgtt atatatttct gcggcctgta
    12721 cggatgcaga tgccacaatg cccatcacca ctaatgccag agtgctcttt ttcattttca
    12781 ttcctgattt taattaacgc gcgaatattc agcgggagag ccccgttgaa aacaggaaag
    12841 tttttaacct gagattgtta aagatatatt acagattaat aatattctta aaatgtggta
    12901 atttattaaa tctgtaataa aagcgtaaac aactgccgct aggcttgctg
//
LOCUS       DAPGUL010000380         7265 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.guided.183, whole genome shotgun sequence.
ACCESSION   DAPGUL010000380 DAPGUL010000000
VERSION     DAPGUL010000380.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7265
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.guided.183"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            218..1021
                     /locus_tag="RHX21_005052"
                     /note="aph(3'')-Ib"
     CDS             218..1021
                     /locus_tag="RHX21_005052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010890156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(3'')-Ib"
                     /protein_id="HDV1990067.1"
                     /translation="MNRTNIFFGESHSDWLPVRGGESGDFVFRRGDGHAFAKIAPASR
                     RGELAGERDRLIWLKGRGVACPEVINWQEEQEGACLVITAIPGVPAADLSGADLLKAW
                     PSMGQQLGAVHSLSVDQCPFERRLSRMFGRAVDVVSRNAVNPDFLPDEDKSTPQLDLL
                     ARVERELPVRLDQERTDMVVCHGDPCMPNFMVDPKTLQCTGLIDLGRLGTADRYADLA
                     LMIANAEENWAAPDEAERAFAVLFNVLGIEAPDRERLAFYLRLDPLTWG"
     gene            1021..1857
                     /locus_tag="RHX21_005053"
     CDS             1021..1857
                     /locus_tag="RHX21_005053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000480972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(6)-Id"
                     /protein_id="HDV1990068.1"
                     /translation="MFMPPVFPAHWHVSQPVLIADTFSSLVWKVSLPDGTPAIVKGLK
                     PIEDIADELRGADYLVWRNGRGAVRLLGRENNLMLLEYAGERMLSHIVAEHGDYQATE
                     IAAELMAKLYAASEEPLPSALLPIRDRFAALFQRARDDQNAGCQTDYVHAAIIADQMM
                     SNASELRGLHGDLHHENIMFSSRGWLVIDPVGLVGEVGFGAANMFYDPADRDDLCLDP
                     RRIAQMADAFSRALDVDPRRLLDQAYAYGCLSAAWNADGEEEQRDLAIAAAIKQVRQT
                     SY"
     gene            2193..3008
                     /locus_tag="RHX21_005054"
     CDS             2193..3008
                     /locus_tag="RHX21_005054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032492145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(3')-Ia"
                     /protein_id="HDV1990069.1"
                     /translation="MSHIQRETSCSRPRLNSNLDADLYGYKWARDNVGQSGATIYRLY
                     GKPDAPELFLKHGKGSVANDVTDEMVRLNWLTAFMPLPTIKHFIRTPDDAWLLTTALP
                     GKTAFQVLEEYPDSGENIVDALAAFLRRLHSIPVSNCPFNSDRVFRLAQAQSRMNNGL
                     VDASDFDDERNGWPVEQVWKEMHKLLPFSPDSVVTHGDFSLDNLIFDEGKLIGCIDVG
                     RVGIADRYQDLAILWNCLGEFSPSLQKRLFQKYGIDNPDMNKLQFHLMLDEFF"
     gene            complement(3162..4037)
                     /locus_tag="RHX21_005055"
     CDS             complement(3162..4037)
                     /locus_tag="RHX21_005055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001201005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA--6-aminopenicillanic acid
                     acyl-transferase"
                     /protein_id="HDV1990070.1"
                     /translation="MRAEVQRHYPHIWQELEGLAQGLEATVDQVFAWNCRGDLVRSTS
                     DGCTTVAGVNAAGERIIAHNEDGFPQLRDECLLATITPSRGLSFTSFAYPGSICGHTF
                     AVNEKGIVNTVNNIRAVYRPQGLPRQILARASLNANTLDEAITILTGQPRSGAFHHTL
                     GQLGDARLFSVEATGQGCSVLPLTTVTGHANHLVHAALAGVEQIVTDSSASRQLRLVQ
                     WRETQPPFDAAAAKTILSDTHDAELPIYRLAADDPDEENTLATAVFTLDANHVRWQIF
                     DINRDDAKFHGEVRG"
     gene            complement(4107..6992)
                     /locus_tag="RHX21_005056"
     CDS             complement(4107..6992)
                     /locus_tag="RHX21_005056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HDV1990071.1"
                     /translation="MPRRVTLTDRQKDALLRLPTSQTDLLKHYTLSDEDLGHIRLRRR
                     AHNRFGFALQLCVLRYPGRVLAPGELIPAEVIEFIGAQLGLGADDLVDYAAREETRHE
                     HLAELRGLYGFRTFSGRGASELKEWLFREAEMAVSNEDIARRFVAECRRTRTVLPATS
                     TIERLCAAALVDAERRIETRIASRLPMSIREQLLALLEETADDRVTRFVWLRQFEPGS
                     NSSSANRLLDRLEYLQRIDLPEDLLAGVPAHRVTRLRRQGERYYADGMRDLPEDRRLA
                     ILAVCVSEWQAMLADAVVETHDRIVGRLYRASERICHAKVADEAGVVRDTLKSFAEIG
                     GALVDAQDDGQPLGDVIASGSGWDGLKTLVAMATRLTATMADDPLNHVLDGYHRFRRY
                     APRMLRLLDLRAAPVALPLLEAVTALRTGLNDAAMTSFLRPSSKWHRHLRAQRAGDAR
                     LWEIAVLFHLRDAFRSGDVWLTRSRRYGDLKHALVPAQSIAEGGRLAVPLRPEEWLAD
                     RQARLDMRLRELGRAARAGTIPGGSIENGVLHIEKLEAAAPTGAEDLVLDLYKQIPPT
                     RITDLLLEVDAATGFTEAFTHLRTGAPCADRIGLMNVILAEGINLGLRKMADATNTHT
                     FWELIRIGRWHVEGEAYDRALAMVVEAQAALPMARFWGMGTSASSDGQFFVATEQGEA
                     MNLVNAKYGNTPGLKAYSHVSDQYAPFATQVIPATASEAPYILDGLLMNDAGRHIREQ
                     FTDTGGFTDHVFAACAILGYRFAPRIRDLPSKRLYAFNPSAAPAHLRALIGGKVNQAM
                     IERNWPDILRIAATIAAGTVAPSQILRKLASYPRQNELATALREVGRVERTLFMIDWI
                     LDAELQRRAQIGLNKGEAHHALKRAISFHRRGEIRDRSAEGQHYRIAGMNLLAAIIIF
                     WNTMKLGEVVANQKRDGKLLSPDLLAHVSPLGWEHINLTGEYRWPKP"
     gene            7118..>7265
                     /locus_tag="RHX21_005057"
     CDS             7118..>7265
                     /locus_tag="RHX21_005057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDV1990072.1"
                     /translation="MLIGYARVSKADGSQSLDLQHDALRAAGVERDNIYDGTVAKLAM
                     RQPFV"
BASE COUNT         1549 a         2005 c         2090 g         1621 t
ORIGIN      
        1 cttaatgatt ttgataaaaa tcattagggg attcatcagc actcggctgg aaatcgccgg
       61 tggcatttga gaaaaaagcc gcttaaaatg agagatagac cggaacacaa ccggtgcaag
      121 accatggaaa gcatgttctc ggacttacgt agcaactcgt ttcttttcgc aggttgagcc
      181 acctccgcgc ttcatcagaa aactgaagga acctccattg aatcgaacta atattttttt
      241 tggtgaatcg cattctgact ggttgcctgt cagaggcgga gaatctggtg attttgtttt
      301 tcgacgtggt gacgggcatg ccttcgcgaa aatcgcacct gcttcccgcc gcggtgagct
      361 cgctggagag cgtgaccgcc tcatttggct caaaggtcga ggtgtggctt gccccgaggt
      421 gatcaactgg caggaggaac aggagggtgc atgcttggtg ataacggcaa ttccgggagt
      481 accggcggct gatctgtctg gagcggattt gctcaaagcg tggccgtcaa tggggcagca
      541 acttggcgct gttcacagcc tatcggttga tcaatgtccg tttgagcgca ggctgtcgcg
      601 aatgttcgga cgcgccgttg atgtggtgtc ccgcaatgcc gtcaatcccg acttcttacc
      661 ggacgaggac aagagtacgc cgcagctcga tcttttggct cgtgtcgaac gagagctacc
      721 ggtgcggctc gaccaagagc gcaccgatat ggttgtttgc catggtgatc cctgcatgcc
      781 gaacttcatg gtggacccta aaactcttca atgcacgggt ctgatcgacc ttgggcggct
      841 cggaacagca gatcgctatg ccgatttggc actcatgatt gctaacgccg aagagaactg
      901 ggcagcgcca gatgaagcag agcgcgcctt cgctgtccta ttcaatgtat tggggatcga
      961 agcccccgac cgcgaacgcc ttgccttcta tctgcgattg gaccctctga cttggggttg
     1021 atgttcatgc cgcctgtttt tcctgctcat tggcacgttt cgcaacctgt tctcattgcg
     1081 gacacctttt ccagcctcgt ttggaaagtt tcattgccag acgggactcc tgcaatcgtc
     1141 aagggattga aacctataga agacattgct gatgaactgc gcggggccga ctatctggta
     1201 tggcgcaatg ggaggggagc agtccggttg ctcggtcgtg agaacaatct gatgttgctc
     1261 gaatatgccg gggagcgaat gctctctcac atcgttgccg agcacggcga ctaccaggcg
     1321 accgaaattg cagcggaact aatggcgaag ctgtatgccg catctgagga acccctgcct
     1381 tctgcccttc tcccgatccg ggatcgcttt gcagctttgt ttcagcgggc gcgcgatgat
     1441 caaaacgcag gttgtcaaac tgactacgtc cacgcggcga ttatagccga tcaaatgatg
     1501 agcaatgcct cggaactgcg tgggctacat ggcgatctgc atcatgaaaa catcatgttc
     1561 tccagtcgcg gctggctggt gatagatccc gtcggtctgg tcggtgaagt gggctttggc
     1621 gccgccaata tgttctacga tccggctgac agagacgacc tttgtctcga tcctagacgc
     1681 attgcacaga tggcggacgc attctctcgt gcgctggacg tcgatccgcg tcgcctgctc
     1741 gaccaggcgt acgcttatgg gtgcctttcc gcagcttgga acgcggatgg agaagaggag
     1801 caacgcgatc tagctatcgc ggccgcgatc aagcaggtgc gacagacgtc atactagata
     1861 tcaagcgact tctcctatcc cctgggaaca catcaatctt accggagaat atcgttggcc
     1921 aaagccttag cgtaggattt cgccctctcc cgcaaacgac ccctttattg taggtgggcc
     1981 agttggtgat tttgaacttt tgctttgcca cggaacggtc tgcgttgtcg ggaagatgcg
     2041 tgatctgatc cttcaactca gcaaaagttc gatttattca acaaatccac gttgtgtctc
     2101 aaaatctctg atgttacatt gcacaagata aaaatatatc atcatgaaca ataaaactgt
     2161 ctgcttacat aaacagtaat acaaggggtg ttatgagcca tattcaacgg gaaacgtctt
     2221 gctcgaggcc gcgattaaat tccaacctgg atgctgattt atatgggtat aaatgggctc
     2281 gcgataatgt cgggcaatca ggtgcgacaa tctatcgatt gtatgggaag cccgatgcgc
     2341 cagagttgtt tctgaaacat ggcaaaggta gcgttgccaa tgatgttaca gatgagatgg
     2401 tcagactaaa ctggctgacg gcatttatgc ctcttccgac catcaagcat tttatccgta
     2461 ctcctgatga tgcatggtta ctcaccactg cgctccccgg gaaaacagca ttccaggtat
     2521 tagaagaata tcctgattca ggtgaaaata ttgttgatgc gctggcagcg ttcctgcgcc
     2581 ggttgcattc gattcctgtt agtaattgtc cttttaacag cgatcgcgta tttcgtctcg
     2641 ctcaggcgca atcacgaatg aataacggtt tggttgatgc gagtgatttt gatgacgagc
     2701 gtaatggctg gcctgttgaa caagtctgga aagaaatgca taagcttttg ccattctcac
     2761 cggattcagt cgtcactcat ggtgatttct cacttgataa ccttattttt gacgagggga
     2821 aattaatagg ttgtattgat gttggacgag tcggaatcgc agaccgatac caggatcttg
     2881 ccatcctatg gaactgcctc ggtgaatttt ctccttcatt acagaaacgg ctttttcaaa
     2941 aatatggtat tgataatcct gatatgaata aattgcagtt tcatttgatg ctcgatgagt
     3001 ttttctgata gttagtcttt gtagagacac aaacctgaaa ttccggacac cgcgcttcag
     3061 gacatctccc tggacgccga tatctggcag tatccggacg gtactatcga acgccgggcc
     3121 aacggtactc ccctgccctt tatgactgac gaccggctat ttcacccacg cacttctcca
     3181 tgaaatttag catcgtcgcg gttaatgtcg aaaatttgcc acctgacgtg gttggcatcg
     3241 agggtgaaaa ctgccgtggc gagggtgttc tcctcatccg gatcgtcggc agccagccgg
     3301 taaattggca gttctgcgtc atgggtatct gagagaatgg tttttgccgc cgcggcgtca
     3361 aacggaggtt gcgtttcccg ccactgcacg aggcgtaact gccgcgacgc tgaactgtcg
     3421 gtaacgatct gctcaacgcc agccagtgcc gcatgcacca gatggttggc atgcccggtt
     3481 accgtcgtca ggggtagaac ggaacagcct tgaccggtgg cctcaacgct gaacagccgc
     3541 gcatcgccca gctgcccgag cgtatggtga aacgccccgg atcgcggctg gccggtaagt
     3601 atagtgatgg cctcgtcgag ggtgttcgca ttcagcgagg cgcgagccag gatctgacgc
     3661 ggtaatccct gcggacgata cactgcacgg atgttattca ccgtgttaac gatacctttt
     3721 tcatttaccg caaaggtgtg gccgcaaatc gaccccggat aggcaaaact cgtaaagctc
     3781 agaccgcgac tcggagtaat ggtagccagc aagcattcat cccgtaactg aggaaaaccg
     3841 tcttcattat gcgcgataat ccgctcgcct gcggcgttta ccccggccac cgtcgtacag
     3901 ccatccgacg ttgagcgcac cagatcgcca cggcagttcc aggcaaagac ctgatcaaca
     3961 gtggcctcca gtccctgcgc cagcccctcc agctcctgcc agatgtgcgg ataatgccgc
     4021 tgcacctcgg cgcgcattaa ccgggtctca ggggatgcct gcagggtcat cacggggtcg
     4081 tttgcgggag ggggcggaat cctacgctaa ggctttggcc agcgatattc tccggtgaga
     4141 ttgatgtgtt cccatccgag cggcgaaaca tgggccaaga gatcgggcga tagcagcttt
     4201 ccatcgcgtt tctggtttgc aacgacctcg ccgagcttca tggtgttcca gaagatgatg
     4261 atggcggcga gcagattcat gccggcgatg cggtaatgct ggccttcggc ggaacggtcg
     4321 cggatttcac cgcggcggtg gaagctgatt gcccgcttca gcgcatgatg agcttcgcct
     4381 ttgttgagcc cgatctgggc acgccgttgg agttcggcat ccagaatcca gtcgatcatg
     4441 aacagggtgc gctcgacgcg accgacttcc cgcagggctg tcgcgagctc gttctgccgc
     4501 ggataggagg cgagtttccg cagaatctgg cttggcgcga cggtcccggc agcaatggtg
     4561 gcggcgatgc gcaggatgtc gggccaattg cgctcgatca tggcttggtt gacctttccg
     4621 ccgatcaacg ctcgcaggtg cgccggggcg gccgacggat tgaacgcgta gagccgtttg
     4681 gatggcaggt cgcggatgcg cggagcgaac cggtagccga gaatggcaca tgcggcaaag
     4741 acgtgatcgg tgaagccgcc cgtgtcggtg aactgctcgc ggatatggcg tccagcatcg
     4801 ttcatcagca ggccatcgag gatgtaaggc gcttcgcttg ccgttgcagg aatcacctgg
     4861 gttgcgaacg gcgcatattg gtcggagacg tggctatagg ctttcaggcc cggggtattg
     4921 ccatatttcg cgttgaccag gttcatggcc tcaccttgct ctgtagcgac gaagaactgt
     4981 ccgtcgctcg aagccgacgt gcccatgccc cagaaccggg ccatgggtaa cgctgcctgt
     5041 gcctcgacca ccatggccag cgcccggtca taggcttcgc cctcgacatg ccaccgtcca
     5101 atgcggatca attcccagaa ggtgtgggtg tttgtcgcat ccgccatttt gcgcaagccg
     5161 aggttgatcc cttccgccaa gataacgttc attagcccga tccggtcagc gcagggtgct
     5221 cctgtgcgca gatgggtgaa cgcttcggtg aagccggtcg ccgcatccac ctccagcagg
     5281 agatcggtga tgcgcgtggg cgggatctgc ttgtagagat cgagcaccag atcttcggcg
     5341 cctgtcggcg cggcggcttc gagtttctcg atatgcagaa cgccgttttc aatcgacccg
     5401 cccgggatcg tgcctgcgcg agcggcacgg ccaagctcgc gcaaccgcat gtcgaggcga
     5461 gcttgccggt ctgccagcca ttcctccggc cgcaatggca cagcgagacg accgccttcc
     5521 gcgatggatt gtgccggaac gagtgcgtgt ttcagatcgc catagcgccg ggacctagta
     5581 agccagacat ctccggagcg gaacgcatcg cgcagatgga acagcaccgc gatctcccat
     5641 aggcgagcgt cgccagccct ctgggcccga aggtggcgat gccatttcga gctgggccgc
     5701 aagaagctgg tcatcgcggc atcgttcaaa ccggtacgaa gggccgtcac cgcttccaga
     5761 agcggcagtg caacgggcgc agctcgcaga tcgagcaggc gcaacatgcg tggagcgtat
     5821 cggcggaagc ggtgataacc gtcgagcaca tgattgagcg gatcgtcggc catggtggcg
     5881 gtcagcctgg ttgccattgc aacaagggtt tttaagccgt cccaccctga cccactcgcg
     5941 atgacatcgc ccagcggctg gccatcatcc tgtgcatcga ccagggcgcc cccgatctcg
     6001 gcgaaggatt tcagggtgtc acgcaccacc cccgcttcgt ctgcgacctt tgcatggcaa
     6061 atacgctccg aagcacggta gagacggccg acgatccggt cgtgggtttc gaccactgcg
     6121 tcggccaaca tcgcctgcca ttccgagacg caaacagcca agatcgcaag ccgcctgtcc
     6181 tccgggagat cgcgcatgcc gtcggcataa taccgttcac cctgcctgcg cagacgagtc
     6241 acccgatggg caggaacgcc ggcaagcaga tcctcgggga gatcgatgcg ttgcagatat
     6301 tcgagccggt cgagcagccg gttggccgac gaagagttcg agccaggctc gaactggcgc
     6361 agccacacaa aacgggtcac ccgatcatca gccgtctcct cgagcaatgc cagcaactgt
     6421 tctcggatcg acataggcag ccgactggcg atcctcgtct cgatgcgtcg ctcggcatcg
     6481 acgagagccg cggcacaaag ccgctcgatc gtggatgtcg cgggaaggac agtgcgggtg
     6541 cgtcggcact cggctacgaa gcgacgggcg atatcctcgt tcgacaccgc catctcggct
     6601 tctcggaaca accattcctt cagctcgctc gcaccacgtc cggagaaggt gcggaagccg
     6661 tagagccccc gtaactcggc aagatgctcg tgccgtgttt cctcgcgggc agcatagtct
     6721 acgagatcgt cggcacccag gccaagctgc gctccgataa attcgatgac ctctgcaggg
     6781 atcagttcgc ctggagccag cacccggccg ggatagcgca ggacacacaa ttgcagggcg
     6841 aagccgaacc tgttgtgagc gcgccgacgc agcctgatat gcccaaggtc ttcatcactc
     6901 agcgtatagt gcttgagcaa atccgtctgt gaagtcggca agcgcaacag cgcgtctttc
     6961 tgccgatcgg ttagagtgac gcgacgcggc atacatgttc ctttttcaaa atctgatagc
     7021 gttcaagacg ctttgtttat gaagctggtt gagatacact tccagaggtc aatgcaatcg
     7081 tggccgaagc gccgcctcaa accaacgttt gtgatacatg ctgatcggat atgcccgcgt
     7141 ctccaaagcc gatggctcgc agtctctcga cctgcagcac gacgccttgc gcgccgcagg
     7201 tgtcgaacgg gacaatatct atgatggcac tgttgcaaag ttagcgatga ggcagccttt
     7261 tgtct
//
LOCUS       DAPGUL010000381         3778 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.guided.237, whole genome shotgun sequence.
ACCESSION   DAPGUL010000381 DAPGUL010000000
VERSION     DAPGUL010000381.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3778
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.guided.237"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            146..466
                     /locus_tag="RHX21_005058"
     CDS             146..466
                     /locus_tag="RHX21_005058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDV1990073.1"
                     /translation="MIAVIFEVQIQPDQQTRYLTLAEELRPLLSHVAGFISIERFQSL
                     ATEGKMLSLSWWENEYAVLQWKNHVLHAKAQQEGRESIFDFYKISIAHITREYSFKKD
                     KDNV"
     gene            459..845
                     /locus_tag="RHX21_005059"
     CDS             459..845
                     /locus_tag="RHX21_005059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid-binding protein"
                     /protein_id="HDV1990074.1"
                     /translation="MFDVHVVLDNQIGQLALLGKTLGNKGIGLEGGGIFTVGDECHAH
                     FLVEQGKEAKIALEQAGLLVLAIRTPLIRKLKQEKPGELGEIARVLAENNINILVQYS
                     DHANQLILITDNDSMAASVTLPWAIK"
     gene            853..1539
                     /locus_tag="RHX21_005060"
     CDS             853..1539
                     /locus_tag="RHX21_005060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDV1990075.1"
                     /translation="MANLIRKEVTFESSIAAIGAAMSDISRVKILSALMDGRAWTATE
                     LSSVANISASTASSHLSKLLDCQLITVVAQGKHRYFRLAGKDIAELMESMMGISLNHG
                     VHAKVSTPVHLRKARTCYDHLAGEVAVKIYDSLCQQQWITENGSMITLSGIQYFHEMG
                     IDVPSKHSRKICCACLDWSERRFHLGGYVGAALFSLYESKGWLTRHLGYREVTITEKG
                     YAAFKTHFHI"
     gene            complement(1517..2140)
                     /gene="tetR(B)"
                     /locus_tag="RHX21_005061"
     CDS             complement(1517..2140)
                     /gene="tetR(B)"
                     /locus_tag="RHX21_005061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional
                     repressor TetR(B)"
                     /protein_id="HDV1990076.1"
                     /translation="MSRLDKSKVINSALELLNEVGIEGLTTRKLAQKLGVEQPTLYWH
                     VKNKRALLDALAIEMLDRHHTHFCPLEGESWQDFLRNNAKSFRCALLSHRDGAKVHLG
                     TRPTEKQYETLENQLAFLCQQGFSLENALYALSAVGHFTLGCVLEDQEHQVAKEERET
                     PTTDSMPPLLRQAIELFDHQGAEPAFLFGLELIICGLEKQLKCESGS"
     gene            2222..3427
                     /gene="tet(B)"
                     /locus_tag="RHX21_005062"
     CDS             2222..3427
                     /gene="tet(B)"
                     /locus_tag="RHX21_005062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001089064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(B)"
                     /protein_id="HDV1990077.1"
                     /translation="MNSSTKIALVITLFDAMGIGLIMPVLPTLLREFIASEDIANHFG
                     VLLALYALMQVIFAPWLGKMSDRFGRRPVLLLSLIGASLDYLLLAFSSALWMLYLGRL
                     LSGITGATGAVAASVIADTTSASQRVKWFGWLGASFGLGLIAGPIIGGFAGEISPHSP
                     FFIAALLNIVTFLVVMFWFRETKNTRDNTDTEVGVETQSNSVYITLFKTMPILLIIYF
                     SAQLIGQIPATVWVLFTENRFGWNSMMVGFSLAGLGLLHSVFQAFVAGRIATKWGEKT
                     AVLLGFIADSSAFAFLAFISEGWLVFPVLILLAGGGIALPALQGVMSIQTKSHQQGAL
                     QGLLVSLTNATGVIGPLLFAVIYNHSLPIWDGWIWIIGLAFYCIIILLSMTFMLTPQA
                     QGSKQETSA"
     gene            complement(3540..>3778)
                     /locus_tag="RHX21_005063"
     CDS             complement(3540..>3778)
                     /locus_tag="RHX21_005063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDV1990078.1"
                     /translation="NELEKISLEYITGKVNAIVSKLIQENQLKAYDDDVLKNLLNGWF
                     MHIAIHAKNLKELADKKGQFIAIYRGFLLSLKDK"
BASE COUNT         1050 a          691 c          820 g         1217 t
ORIGIN      
        1 aacatgataa gcgcaggccg agcaatttaa agaagtgtga tatacaacat aaaacagcag
       61 catgaccttt ctatatttcg ttgcttatcg aagtgttaat tttcgggtgg attactctgt
      121 ttgttgatta ataacggaga aaaatatgat tgctgtaata tttgaggtgc aaatacaacc
      181 cgaccaacaa actcgctatt tgactttagc tgaggagtta agaccactat taagtcatgt
      241 agctggtttt atttcaattg aacgttttca aagtctagct acagaaggaa aaatgttatc
      301 gctatcttgg tgggaaaacg aatacgcagt tctgcaatgg aaaaatcatg ttttacatgc
      361 gaaagctcaa caagaagggc gagagtcaat atttgatttt tacaaaatta gtattgctca
      421 tattactcgc gaatattcat ttaaaaagga caaggataat gtttgatgtt cacgttgttt
      481 tagataatca aataggacaa ttagcattac taggaaaaac attaggtaat aaaggtattg
      541 gattggaagg gggagggata tttacggttg gtgatgaatg ccatgctcat tttcttgttg
      601 aacaaggaaa ggaagctaaa atagcgctag agcaagctgg actgttagta cttgcgatcc
      661 ggacaccatt aattcgtaag ttaaaacagg aaaaaccggg ggaacttggc gaaatagcac
      721 gagtattggc ggagaataac attaatattt tagtgcaata cagtgaccat gctaaccaac
      781 tgatattaat aacggacaat gatagtatgg ctgcatctgt tacgctccct tgggcaataa
      841 agtgaacttg cgatggctaa tttaatacga aaagaggtta cctttgagtc ctcaatagcc
      901 gcgatagggg cggctatgtc tgacatttca cgagttaaaa tactcagtgc tttgatggat
      961 gggcgagctt ggacggccac tgagctaagt tctgtggcga atatatcagc ttcaacggcg
     1021 agcagtcatt tatctaaatt attagattgc cagctaatca cagtagtagc tcaaggcaag
     1081 catcgttatt ttcggctagc aggaaaagat attgctgaat tgatggaaag tatgatgggg
     1141 atctccttaa accatggcgt acatgccaaa gtttccacgc cagtgcattt acgaaaagca
     1201 cgtacttgct atgatcattt agctggcgaa gttgccgtta agatctatga ttccctttgt
     1261 caacagcaat ggatcactga aaatggttca atgatcacat taagtggtat tcaatatttt
     1321 catgaaatgg gaattgacgt tccttccaaa cattcacgta aaatctgttg tgcgtgttta
     1381 gattggagtg aacgccgttt ccatttaggt gggtacgttg gagccgcatt attttcgctt
     1441 tatgaatcta aagggtggtt aactcgacat cttggttacc gtgaagttac catcacggaa
     1501 aaaggttatg ctgcttttaa gacccacttt cacatttaag ttgtttttct aatccgcata
     1561 tgatcaattc aaggccgaat aagaaggctg gctctgcacc ttggtgatca aataattcga
     1621 tagcttgtcg taataatggc ggcatactat cagtagtagg tgtttccctt tcttctttag
     1681 cgacttgatg ctcttgatct tccaatacgc aacctaaagt aaaatgcccc acagcgctga
     1741 gtgcatataa tgcattctct agtgaaaaac cttgttggca taaaaaggct aattgatttt
     1801 cgagagtttc atactgtttt tctgtaggcc gtgtacctaa atgtactttt gctccatcgc
     1861 gatgacttag taaagcacat ctaaaacttt tagcgttatt acgtaaaaaa tcttgccagc
     1921 tttccccttc taaagggcaa aagtgagtat ggtgcctatc taacatctca atggctaagg
     1981 cgtcgagcaa agcccgctta ttttttacat gccaatacaa tgtaggctgc tctacaccta
     2041 gcttctgggc gagtttacgg gttgttaaac cttcgattcc gacctcatta agcagctcta
     2101 atgcgctgtt aatcacttta cttttatcta atctagacat cattaattcc taatttttgt
     2161 tgacactcta tcattgatag agttatttta ccactcccta tcagtgatag agaaaagtga
     2221 aatgaatagt tcgacaaaga tcgcattggt aattacgtta ttcgatgcca tggggattgg
     2281 ccttatcatg ccagtcttgc caacgttatt acgtgaattt attgcttcgg aagatatcgc
     2341 taaccacttt ggcgtattgc ttgcacttta tgcgttaatg caggttatct ttgctccttg
     2401 gcttggaaaa atgtctgacc gatttggtcg gcgcccagtg ctgttgttgt cattaatagg
     2461 cgcatcgctg gattacttat tgctggcttt ttcaagtgcg ctttggatgc tgtatttagg
     2521 ccgtttgctt tcagggatca caggagctac tggggctgtc gcggcatcgg tcattgccga
     2581 taccacctca gcttctcaac gcgtgaagtg gttcggttgg ttaggggcaa gttttgggct
     2641 tggtttaata gcggggccta ttattggtgg ttttgcagga gagatttcac cgcatagtcc
     2701 cttttttatc gctgcgttgc taaatattgt cactttcctt gtggttatgt tttggttccg
     2761 tgaaaccaaa aatacacgtg ataatacaga taccgaagta ggggttgaga cgcaatcgaa
     2821 ttcggtatac atcactttat ttaaaacgat gcccattttg ttgattattt atttttcagc
     2881 gcaattgata ggccaaattc ccgcaacggt gtgggtgcta tttaccgaaa atcgttttgg
     2941 atggaatagc atgatggttg gcttttcatt agcgggtctt ggtcttttac actcagtatt
     3001 ccaagccttt gtggcaggaa gaatagccac taaatggggc gaaaaaacgg cagtactgct
     3061 cggatttatt gcagatagta gtgcatttgc ctttttagcg tttatatctg aaggttggtt
     3121 agttttccct gttttaattt tattggctgg tggtgggatc gctttacctg cattacaggg
     3181 agtgatgtct atccaaacaa agagtcatca gcaaggtgct ttacagggat tattggtgag
     3241 ccttaccaat gcaaccggtg ttattggccc attactgttt gctgttattt ataatcattc
     3301 actaccaatt tgggatggct ggatttggat tattggttta gcgttttact gtattattat
     3361 cctgctatcg atgaccttca tgttaacccc tcaagctcag gggagtaaac aggagacaag
     3421 tgcttagtta tttcgtcacc aaatgatgtt attccgcgaa atataatgac cctcttgata
     3481 acccaagagg gcatttttta cgataaagaa gatttagctt caaataaaac ctatctattt
     3541 tatttatctt tcaagctcaa taaaaagccg cggtaaatag caataaattg gcctttttta
     3601 tcggcaagct cttttaggtt tttcgcatgt attgcgatat gcataaacca gccattgagt
     3661 aagtttttaa gcacatcatc atcataagct ttaagttggt tctcttggat caatttgctg
     3721 acaatggcgt ttaccttacc agtaatgtat tcaaggctaa ttttttcaag ttcattcc
//
LOCUS       DAPGUL010000382         2492 bp    DNA     linear   BCT 07-SEP-2023
DEFINITION  TPA_asm: Escherichia coli isolate ARS-CC16454
            SAMN37211012-rid19355463.guided.264, whole genome shotgun sequence.
ACCESSION   DAPGUL010000382 DAPGUL010000000
VERSION     DAPGUL010000382.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN37211012
            Sequence Read Archive: SRR25824993
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 06-SEP-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001875717.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001875717.1
            Genome Coverage       :: 63x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 09/07/2023 04:53:43
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,066
            CDSs (total)                      :: 4,990
            Genes (coding)                    :: 4,832
            CDSs (with protein)               :: 4,832
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 2 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 8
            Pseudo Genes (total)              :: 158
            CDSs (without protein)            :: 158
            Pseudo Genes (ambiguous residues) :: 0 of 158
            Pseudo Genes (frameshifted)       :: 72 of 158
            Pseudo Genes (incomplete)         :: 79 of 158
            Pseudo Genes (internal stop)      :: 37 of 158
            Pseudo Genes (multiple problems)  :: 28 of 158
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2492
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN37211012-rid19355463.guided.264"
                     /isolate="ARS-CC16454"
                     /isolation_source="dairy calf feces"
                     /db_xref="taxon:562"
                     /country="USA"
                     /collection_date="2017"
                     /collected_by="USDA ARS"
     gene            174..989
                     /gene="sul2"
                     /locus_tag="RHX21_005064"
     CDS             174..989
                     /gene="sul2"
                     /locus_tag="RHX21_005064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfonamide-resistant dihydropteroate synthase
                     Sul2"
                     /protein_id="HDV1990079.1"
                     /translation="MNKSLIIFGIVNITSDSFSDGGRYLAPDAAIAQARKLMAEGADV
                     IDLGPASSNPDAAPVSSDTEIARIAPVLDALKADGIPVSLDSYQPATQAYALSRGVAY
                     LNDIRGFPDAAFYPQLAKSSAKLVVMHSVQDGQADRREAPAGDIMDHIAAFFDARIAA
                     LTGAGIKRNRLVLDPGMGFFLGAAPETSLSVLARFDELRLRFDLPVLLSVSRKSFLRA
                     LTGRGPGDVGAATLAAELAAAAGGADFIRTHEPRPLRDGLAVLAALKETARIR"
     gene            1026..1604
                     /locus_tag="RHX21_005065"
                     /pseudo
     CDS             1026..1604
                     /locus_tag="RHX21_005065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001334685.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4238 domain-containing protein"
     gene            complement(1780..2124)
                     /locus_tag="RHX21_005066"
     CDS             complement(1780..2124)
                     /locus_tag="RHX21_005066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection protein"
                     /protein_id="HDV1990080.1"
                     /translation="MKNLLDTEGTVLFPFQTEIHFIWTIFSTVKRLVIGTRDHICQKQ
                     YWSACLCILLLMAYVGLCAAVVWFVVPWLKAFIVSKFAVSALWVTPVKRGLLWGIGKV
                     VTATCRRFTLLK"
BASE COUNT          555 a          667 c          660 g          610 t
ORIGIN      
        1 gccacaccac gatttgcagc cgccaggctg ccgtggttca tggttaggtt ttgcgatagt
       61 atatttacga gctgattaag gtttggcata gtgtggttcg taagaaaaat tactattatg
      121 ccttgtcctt agtcagcttt tttgtttttt gtcgtgtaca gagagaagcc cccatgaata
      181 aatcgctcat cattttcggc atcgtcaaca taacctcgga cagtttctcc gatggaggcc
      241 ggtatctggc gccagacgca gccattgcgc aggcgcgtaa gctgatggcc gagggggcag
      301 atgtgatcga cctcggtccg gcatccagca atcccgacgc cgcgcctgtt tcgtccgaca
      361 cagaaatcgc gcgtatcgcg ccggtgctgg acgcgctcaa ggcagatggc attcccgtct
      421 cgctcgacag ttatcaaccc gcgacgcaag cctatgcctt gtcgcgtggt gtggcctatc
      481 tcaatgatat tcgcggtttt ccagacgctg cgttctatcc gcaattggcg aaatcatctg
      541 ccaaactcgt cgttatgcat tcggtgcaag acgggcaggc agatcggcgc gaggcacccg
      601 ctggcgacat catggatcac attgcggcgt tctttgacgc gcgcatcgcg gcgctgacgg
      661 gtgccggtat caaacgcaac cgccttgtcc ttgatcccgg catggggttt tttctggggg
      721 ctgctcccga aacctcgctc tcggtgctgg cgcggttcga tgaattgcgg ctgcgcttcg
      781 atttgccggt gcttctgtct gtttcgcgca aatcctttct gcgcgcgctc acaggccgtg
      841 gtccggggga tgtcggggcc gcgacactcg ctgcagagct tgccgccgcc gcaggtggag
      901 ctgacttcat ccgcacacac gagccgcgcc ccttgcgcga cgggctggcg gtattggcgg
      961 cgctgaaaga aaccgcaaga attcgttaac tgcacattcg ggatatttct ctatattcgc
     1021 ggttcactaa agagcaggcc atggaaaccc tgggcctgtc gtccgggggc gataccaagg
     1081 atatttttct gcggcagctc gtccagcagg tgtcacatat tgatctcctg ctgaaaaagg
     1141 actggtacct tctggaaacc aggccagaac gtccgtttta cgtatcagac aatcccgtag
     1201 tgcttaagaa cagcaatgac ttcggtccgt acggtaatct tggtctggcc gttcgcggga
     1261 tacagattta cctccccctg tcatcgacgc tgatgctggc catgtattgc ccctccatcc
     1321 gtgaacagat ggttcgtcaa aagcagcatc ttcaacatct gctcgccagg gcgccgcatc
     1381 ttatcccccg tcacattcgg ccttttgaaa gactggaaca tatccggagg tatacggact
     1441 atcttcttat gccgcttacc ccggagcatg tcacgcatta caattccctg caggtggagt
     1501 tcgcggagca gtacgtgttc tgcggtgaaa aggatttctc tctggttgag agaatgctgg
     1561 ccgatagtga acgctaccgg actggcccgc ggtttacgtt ttagtccgaa ttccggcctc
     1621 acctgtgccg gaaaatgacg gcgggagccc ctgttgtaca gaggagtttt gccgtgttgc
     1681 acccacgcga aagcggcagt ggtcacaggg accaccgccg taaggagatg gtgagtatct
     1741 gttgacattc accatcagtt cgtgtagcgt tgcggctact tactttagca gagtaaatct
     1801 tcggcaagtg gcggtaacca ctttaccgat accccagagt agtccgcgct ttactggcgt
     1861 gacccatagt gccgaaaccg caaatttcga cactataaag gccttcagcc agggcactac
     1921 aaaccagacc accgcagcac agagacccac ataggccata agaagcaaaa tacagagaca
     1981 ggcgctccag tattgcttct ggcaaatatg gtccctggtt ccgataacca ggcgtttaac
     2041 ggtggagaaa atcgtccaaa taaaatggat ttcagtctgg aatgggaata gaaccgttcc
     2101 ctcggtgtct aacaagtttt tcatagaacc ctcccgggta agtatttaca aaagtaactg
     2161 tcttgatttt ggtcatctca ataacctcgt ttttaagtca aaaggcaccc ggcgcctcac
     2221 acacgtgaac gctgttaatg ccgtacagaa tgttttatct ttcagctctg ttatgatgtg
     2281 ttcattcgca tcctcctgtt tgtcataccg attttaagct cgttccgggg gctccccgga
     2341 aaaaaatcca aaaaaatccg ggccggaatg gtgataacca gtctggcggg aaataaacgg
     2401 atcttgttgg ggtggagcgg gacggaacaa tactatgaga gtaatgttaa cagaaatcac
     2461 cgcctttgtc aaggcgcact tatccattaa ag
//
